RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Artificial Intelligence for in vitro fertilisation.' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

At MIM Solutions, we are using artificial intelligence and machine learning to address the worldwide fertility disorder occurring in an increasing number of countries.Specifically, we are developing two solutions - EMBRYOAID (https://www.mim-solutions.ai/embryoaid/) and FOLLISCAN (https://www.mim-solutions.ai/folliscan/) that utilize AI to help couples struggling with infertility to conceive.We have been developing those technologies for 2 years now and we have developed our MVP that are ready to be certified and commercialized. However, this is an enormous organisational, financial and startegic challenge for MIM Solutions.  Short about the company: The company is the first spin-off of the Faculty of Mathematics, Informatics and Mechanics of the University of Warsaw. We are committed to combining rigorous scientific research with solutions to real-world problems. We provide organizations with the most efficient and, at the same time, the safest ML technology, remaining at the forefront of scientific research in this field. Founder-led and with the majority of PhDs, MIM Solutions has one of the most experienced teams of AI and ML experts in Poland.Awards: Innovator of the Year Award awarded by the University of Warsaw 2022, Central European BioForum Award 2022 in the BioDigital category.


**Keywords:** Machine Learning, Deep Learning, In Vitro Fertilization, ART, Prediction System, Recommendation System, Embriology, Reproductive Medicine, Artificial Intelligence, IVF, Women's Health, Medtech
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Understanding the autophagy-linked disorder BPAN: an integrated approach for studying developmental basis of neurodegenerative diseases' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Understanding the fundamental basis of brain disorders is a one of the greatest challenges of the 21st century. Large-scale genetic studies have identified numerous genes with associated roles in both neurodevelopmental and neurodegenerative disorders, suggesting that common mechanisms are involved in the different phases of the same disease. Autophagy is such mechanism, which dysfunction during development or in adult can lead to neurodegenerative diseases, including   beta-propeller protein-associated neurodegeneration (BPAN). BPAN is a disease caused by loss-of-function mutations of the autophagy-related gene Wdr45 resulting in neurodevelopmental defects and neurodegenerative phenotypes. Although BPAN is a rare disease, it represents a genetically simple model to understand the contribution of developmental defects during neurodegenerative disease. To answer these questions, we will use Drosophila that provides unequaled experimental power for generating models of human neurological diseases and establishing their molecular genetic basis. Here, using CRISPR/cas9-made Wdr45 null mutant flies generated by Mollereau and col., I examined human Wdr45-linked phenotypes in Drosophila. I found adult-onset neurodegenerative phenotypes including age-related locomotion decline as well as an abnormal hyperkinetic movements in the embryos of Wdr45 mutants. Therefore, targeting Wdr45 in Drosophila, we aim not only to allow identifying the developmental and neural basis of autophagy-associated neurodegeneration, but also to uncovering the disease molecular responses that are prior to the appearance of neurodegenerative syndromes. Ultimately, findings of our proposal can help find early disease biomarkers and design therapies for broad range of neurological disorders.


**Keywords:*
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Argentinean Bureau for Enhancing Cooperation with the European Community in the Science, Technology and Innovation Area. Phase II' under Seventh Framework.

assistant: **Concept**

ABEST II was conceived as a natural continuation of the successful ABEST/A-EU 6th Framework Programme project whose main objective was to promote joint participation of Argentinean and European scientists in the activities proposed by the 7th Framework Programme by improving the process of providing information on programmes and funding about cooperation with third countries. ABEST II will deepen these awareness and information activities stressing the promotion of the participation in some specific FP7 Programmes like People and will operate in such a way that after completion, a permanent self-sustained office within the Directorate for International Relations of the Ministry for Science, Technology and Productive Innovation of Argentina and a network of research and development institutions from Argentina and the European Union will continue with the promotion and support of the bilateral cooperation activities. ABEST II will also go beyond ABEST/A-EU through working in some specific objectives like better identifying and demonstrating mutual interest and benefit in S&T cooperation between the EU and Argentina and sharing best practices via joint fora such as workshops and presenting the state of the art and the prospects for cooperation in particular fields. One special activity will be added for promoting the participation of Argentinean SME in FP7 activities. Activities were organized around five Work Packages that will be executed by a team of four institutions from four different countries (Argentina, Italy, France and South Africa). Another four institution from three different countries (Spain, Belgium and Austria) with a long tradition of cooperation with Latin America will participate as members of the Steering Committee providing guidance, advice and experi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Advanced Ablation Characterization and Modelling'.

assistant: **Concept**

As mentioned in the FP7 space call for Europe to be active in space in the long term, be it in earth-orbit or across the solar system, it is essential that space technologies with key capabilities are at its disposal. This goal requires developments by radical innovation which may then lead to “disruptive technologies”. In this frame new thermal shielding and low risk return strategies are defined as European key activities in the future. In Europe the design of spacecraft for high-energetic interplanetary or sample return flights is still performed with big safety margins, which means high mass. This again leads to higher costs and a reduction in scientific payloads or instrumentation.Ablative thermal protection materials are a key technology for current and future space exploration missions. However, the mission feasibility is determined by the materials available, and the development of new materials is performed, essentially, by an iterative trial-and-error process. This is due to the absence of validated predictive models for ablative material behaviour – models are tuned to bulk material properties from tests. For each new material, this tuning has to be redone because the models are not of sufficiently high fidelity to be able to make even small extrapolations. This means that materials cannot be designed to a specification to fulfil the needs of a particular mission. The aim of this project is to make a substantial step towards a predictive model of an ablative thermal protection system by incorporating aspects of high fidelity mesoscale ablator physics within a modular framework.In order to successfully develop such physics modules, the understanding of the fundamental processes occurring within the ablative materials must be improved. To this end, existing abl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Intensified processes for CO2 conversion to sustainable synthetic fuels' (IntensifiedCO2) targeting Horizon Europe.

assistant: **Abstract**

Developing intensified catalytic processes for CO2 conversion may drive their implementation at CO2-producing sites, counteracting current practices of emitting CO2 and waste gases. Converting CO2 to synthetic fuels is a win-win scenario as they are used as sustainable aviation fuel. A leading technology to convert CO2 to synthetic fuels proceeds indirectly via Reverse Water Gas Shift (RWGS) and Fischer-Tropsch Synthesis (FTS). CO2 is first reduced to CO via RWGS and then converted to hydrocarbons via FTS. Based on current chemical engineering practices, four unit operations (two reactors and two intermediate separations) are required. The ambition of the IntensifiedCO2 technology is to intensify the current practice through the reduction of unit operations, without compromising on selectivity towards synthetic fuels. The objectives are to eliminate two separation units for CO2 and H2O and to consolidate two reactors into a single bifunctional (RWGS and FTS) reactor. As such, the IntensifiedCO2 technology will be the first demonstration of metallic cobalt catalysts ‘converting’ CO2 to synthetic fuels in a single reactor. Metallic cobalt catalysts are industrial FTS catalysts, but produce mainly methane from CO2. Attempts thus far on tuning cobalt phases to attain synthetic fuels are unsuccessful, signalling the need for a radical strategy as proposed in IntensifiedCO2. My innovative approach involves coaxing a metallic cobalt FTS catalyst to disregard the presence of CO2 and H2O within the reactor, ensuring its catalytic performance mirrors that of synthesis gas (a mixture of CO and H2) conditions. Ideally, undesired species stay in the reactor's mass transfer zone, while desired species interact in the catalyst's adsorption/reaction/desorption zone. This concept of cus
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Dynamic Nuclear Polarization at ultra-fast sample spinning and ultra-low temperature' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The goal of the project is to develop a new hyperpolarization approach called Magic Angle Spinning Dynamic Nuclear Polarization (MAS-DNP) to reach levels of sensitivity and resolution that have never been achieved, in order to tackle highly relevant chemical and biological questions that remain unanswered so far. Firstly this will provide major advances in NMR crystallography (solving 3D structures by NMR) by showing that distance measurements between nuclei (13C, 15N, etc.) as well as 17O quadrupolar parameters can be extracted from NMR measurements without requiring isotopic labeling. This will be applied to systems that cannot be easily isotopically enriched and for which X-ray analysis is often not suitable. Secondly we propose an innovative strategy to hyperpolarize nuclear spins using MAS-DNP: rather than polarizing the entire system uniformly, we will selectively “light up” regions where we wish to gather important structural information. This will be developed to study protein-ligand interactions (with unprecedented resolution) to answer specific structural questions and potentially impact the field of drug engineering. Finally we will show that the unique experimental setup developed in this project will open up NMR to the routine study of “exotic”, yet ubiquitous and highly informative, nuclei such as 43Ca and 67Zn. Specifically, we will show that MAS-DNP can become a choice technique for the study of diamagnetic metal binding sites, complementing EPR for the study of metalloproteins. These goals will be achieved thanks to the development of original methods and advanced instrumentation, allowing sustainable access to low temperatures (down to 10-20 K) and fast pneumatic sample spinning, under microwave irradiation. We expect to improve the current sensitivity
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Electron Transport Experimental Investigation of Perovskites using Light and Electron Injection at the Nanoscale' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The main goal of EXPLEIN is to unravel the limiting factors in the charge carrier transport in perovskite thin films, stacks, and solar cells, aiming to pre-select suitable material compositions for and optimisation of light-converting devices. First, I will gain deep understanding of the role of grain boundaries  typically limiting charge carrier diffusion due to an increased number of recombination centres  in thin films and lamellae, which I will then apply to interfaces in stacks and devices, ultimately allowing me to monitor and improve the performance of perovskite-based solar cells. The centre piece of this work is a scanning electron microscope equipped with cathodoluminescence (CL) and pulsed electron beam capabilities. I will expand those with electrical sample biasing for operando conditions and develop a novel light in-coupling module. This unique, versatile method will facilitate local injection of electrons and photons into the same sample area, thereby allowing for the in-depth study of the differences in morphology (via in-situ secondary electron imaging), optical (via CL and CL lifetimes) and electrical properties upon selective sub-bandgap-energy illumination, applied electrical bias, and local e-beam placement. The diffusion length, a key parameter for solar cell absorbers, will be measured directly and via CL-lifetimes which I will subsequently link to the samples average grain size of various perovskite compositions. The perovskite database will serve as platform for comparison and exchange of knowledge, ultimately allowing to advance and expand the research field.The multitude of the proposed experiments will allow me to gain new and detailed insights into the micro- and nanoscopic charge carrier transport in several types of perovskites, giving me
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Tissue Transmigration Training Network' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Cardiovascular and cancer-related diseases are the leading causes of human mortality and disability. The underlying mechanisms originate from chronic interstitial cell activation leading to pathological tissue remodelling and malfunction of cells. These depend on three fundamental processes: cell adhesion, migration, and modulation/degradation of the extracellular matrix (ECM), which together determine tissue invasion and remodelling. The proposed ITN Tissue Transmigration Training Network (T3Net) is aimed at promoting excellence in training in these areas, with an emphasis on cutting-edge technologies and complementary skills training. T3Net is very timely and has a multidisciplinary training approach unavailable within a single country of the EU. T3Net will be crucial in bundling current and future European expertise and to thus consolidate the momentary European leadership in these emerging key areas of biomedical research. The academic and industrial partners will provide training in new areas of research including the cell structures mediating invasion such as podosomes and invadopodia, as well as the application of materials sciences, nanotechnology and state-of-the-art in vivo imaging. These techniques will be applied to study ECM-cell interactions, in models encompassing vascular remodelling, immunity, inflammation and bone physiology, as well as the pathophysiology of cancer invasion. T3Net trainees will thus be at the forefront of current research, with innovative, complementary expertise in ECM remodelling and tissue transmigration in physiology and pathology. They will also benefit from valuable complementary skills training including communication, entrepreneurship and intellectual property rights. The strength and appeal of the T3Net proposal thus lies in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Topological Insulator Vertical Cavity Laser Array', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Vertical Cavity Surface Emitting Lasers (VCSELs) are tiny semiconductor lasers, structured as pillars of few-microns diameter on a chip, emitting light from their surface. They are now the most commonly used lasers, e.g., in cell phones, car sensors, data transmission in fiber optic networks. Though widely used, the miniscule size of VCSELs sets a stringent limit on the output power it can generate.  For years, scientists have sought to enhance the power emitted by such devices through combining many tiny VCSELs and attempting to force them to act as a single coherent laser, with limited success. In a recent breakthrough, which appeared in Science magazine, we presented a new scheme to force very many VCSELs to lock together and act as a single coherent laser source. Our breakthrough, a direct outcome of our ERC AdG, employs a unique geometrical arrangement of VCSELs on the chip that forces the light to move in a specific path – a photonic topological insulator platform.We propose to capitalize on the success and construct proof of concept technology that will bring this topological insulator VCSEL array a major step towards commercialization. We will design and construct a highly efficient VCSEL array on a novel topological platform optimized for reliability and scalability to large numbers of emitters, where all the emitters act as a single laser. The topological VCSEL array will be pumped electrically, operating at room temperature, and rely on quantum well optimized for emitting high power per emitter. We will define the topological insulator geometry with a reflectivity-modulation scheme that ensures reliability. Our proposed scheme, anticipated to be ready within 18 months, is scalable to a large number of VCSELs and will be a game changer in a plethora of technol
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Statistical Inference and Malliavin Calculus' to be submitted under Seventh Framework.

assistant: **Abstract**

Eulalia Nualart (the researcher, hereafter) broadly works in the field of Stochastic Calculus of Variations (Malliavin Calculus), and its applications to stochastic differential equations (SDEs) and stochastic partial differential equations (SPDEs). In the last years, she has become interested in two new applications of the Malliavin calculus, which are Statistical Inference for SDEs and applications to Mathematical Finance.The aim of this proposal is to consider two different types of SDES: (i) SDEs driven by the sum of a Brownian motion and a Poisson random measure; (ii) SDEs driven by fractional Brownian motion. The coefficients of both SDEs are assumed to depend on some parameter  that needs to be estimated in the following cases: (a) when the trajectory of the SDE is observed continuously during a fixed time interval; (b) when the trajectory is observed discretely at n fixed times. Both cases will be studied, but the proposal concentrates in case (b), as is a more challenging and realistic problem.The proposal is divided into three research projects whose goals are: (1) Obtain upper and lower bounds for the density of the solution to the two types of SPDEs (i) and (ii), by means of the Malliavin Calculus; (2) Use these bounds in order to prove the local asymptotic normality (LAN) for the models (i) and (ii), and then apply Hajek-Lecam's theorem to obtain asymptotically efficient estimators for the parameter of the equations; (3) Study Monte Carlo methods and exact simulation of the SDE model with jumps (i), and apply these computational methods to the following financial problems: jump volatility models and numerical computations of greeks.In addition to the three research projects, the proposal aims to develop a research network on Stochastic Analysis and applicat