RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'HOMEOSIGN : Homeoprotein signaling during development and in the adult' under Seventh Framework.

assistant: **Concept**

Homeoprotein (HP) signaling designates the ability of HP transcription factors to transfer between cells, thus acting as signaling molecules. We will investigate several properties of this novel signaling pathway in the CNS and how it can shed light on brain development and physiology, also neurological and psychiatric pathologies. The studies will concentrate on 4 HPs (Engrailed1/2, Otx2 and Pax6) illustrative of the HP family and of high physiological interest. Mouse lines will be developed in which the extracellular expression of single chain antibodies against these HPs can be induced at specific places and times, allowing us to follow the consequences of neutralizing extracellular HPs while preserving their cell autonomous functions. With this tool (and others) we shall study if (and how) HP transfer regulates boundary position in the neuroepithelium and direct cell/axon migration and guidance. In postnatal development, we will dissect how Otx2 regulates the opening, closure and reopening of critical periods in the cortex and controls the behavior of neuronal networks throughout life. Also in the adult we will follow how HPs regulate the physiology and survival of distinct neuronal groups, including midbrain dopaminergic neurons. We shall analyze the physiological interactions between HPs and classical signaling molecules and identify HP targets, in particular those regulating the cell energy metabolism, and explore their ability to modulate the epigenetic state of the chromatin. Using Otx2 and Engrailed as baits, we shall identify the complex sugars with which they interact at the cell surface to get an entry into the ""sugar code"" that confers specificity to HP capture by distinct cell populations. This project should identify new HP functions and highlight them
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Interoperable electron Microscopy Platform for advanced RESearch and Services' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

IMPRESS (Interoperable electron Microscopy Platform for advanced RESearch and Services) aims to co-develop and deliver advanced transmission electron microscopy (TEM) instrumentation, methods and tools that will revolutionize the way in which TEMs are used by all new and well-established scientific communities, integrate them with other instrumentation at analytical research infrastructures (RIs) and create new business opportunities for small and medium-sized enterprises. The core of the project is the development of a standardized cartridge-based interoperable platform for TEM that is based on common interfaces and data formats, is flexible and adaptable and allows users to perform advanced correlative experiments using different instruments and to co-develop methodological options that are not yet satisfied by commercially available electron microscopes. The solutions will be delivered at technology readiness level 8 through a pre-commercial procurement. The project also involves the co-development of new electron sources, techniques based on adaptive optics and event-driven detectors, application-relevant in situ/operando sample environments and software for simulation of experiments and remote access based on artificial intelligence. By the end of the project, these developments will be integrated with the new cartridge-based platform, in order to make them available to all users of RIs and other TEMs owners. An open knowledge and innovation hub for TEM will be created and a training programme will promote the new solution, to initiate RI staff in their use and to provide both materials and life science communities with optimized tools for tackling societal challenges, especially in the energy and health sectors. The project will exploit synergies and collaboration
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Solutions for CRitical Raw materials - a European Expert Network 2' under Horizon 2020.

assistant: **Concept**

In order to secure the sustainable access to primary and secondary raw materials and particularly Critical Raw Materials (CRMs) in the EU, there is a need for an expert advice to better understand the value chains of the raw materials screened in the CRMs assessment. Making this information freely available, through the SCRREEN knowledge database and the EC Raw Materials Information System, will support decision-making at the EU level on the CRM strategies.In the continuation of SCRREEN, SCRREEN2 will develop and strengthen the SCRREEN expert network in order to cover all raw materials screened in the CRM 2020 assessment. The work was initiated in 2019 to support the EC (validation workshop and creation of an expert database). The SCRREEN network gathers today expertise on primary and secondary resources; production, including exploration, mining, processing, recycling and refining; substitution of CRM; raw materials markets; future demand and supply; materials flows; socio-economic analysis. It covers also strategic value chains and end-use sectors, including batteries, e-mobility, renewable energy, electronics, defence and aerospace.Thanks to clustering and cooperation with other projects/initiatives, SCRREEN2 will develop this network to fill the existing gaps and to mobilize it on two axes through dedicated workshops. First, in order to improve data and knowledge on all screened raw materials, SCRREEN2 will update on a regular basis the raw materials factsheets. It will also publish sector-oriented outlook reports analysing the future supply and demand of raw materials, policy and technology gaps and innovation potential along the raw materials value chains. A work-plan, updated every 6 months, will allow SCRREEN2 to flexibly support the Commission in policy-making
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Epigenetics, Experience and Responsibility: Implications for neurodevelopmental disorders'.

assistant: **Innovation**

In folk psychology and in bioethical discussions, the central dogma of genetics is often taken for granted: humans are seen as defined in a genetic blueprint. The conceptualization of psychiatric conditions as innate or acquired, biological or psychosocial, genetic or environmental, influences the ascription of both capacity responsibility (the capacity to adapt or adjust one’s own behavior) and normative responsibility of individuals or the society towards those diagnosed. But findings in the field of epigenetics indicate that the social and physical environment influence how genes are expressed. Indeed, epigenetics may shed a new light on distinctions such as innate/acquired, genetic/environmental, biological/psychosocial: a far more complex view on neurodevelopmental disorders may emerge, with ethical implications. However, the implications of epigenetics for discussions on the scope and extent of normative responsibility have not been adequately addressed. NEUROEPIGENETHICS aims to investigate the ethical implications of epigenetics for neurodevelopmental disorders. We will use theoretical and empirical methods to investigate how certain concepts (innate/biological/genetic) affect the ways in which professionals and stakeholders (persons with a neurodevelopmental disorder and their families) conceive of responsibility. We will evaluate how the emerging field of epigenetics alters the ascription of capacity responsibility and normative responsibility. We will research how individuals with Autism Spectrum Disorder (ASD), Tourette Syndrome (TS) and Attention Deficit Hyperactivity Disorder (ADHD)and their families experience the interaction between their condition and their biological and social environment. Finally, we will define moral responsibility in light of the e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Extreme Light Infrastructure Preparatory Phase' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Among the most significant scientific inquiries defined by Science (July 2005) was whether or not scientists will be able to build a laser of intensity sufficient to “rip photons into electron-positron pairs.”  ELI will be the first infrastructure to approach this limit. It represents the consensual effort of 13 European countries, more than 50 laboratories and numerous international collaborators. Dedicated to the fundamental study of laser-matter interaction in a new and unsurpassed, “ultra-relativistic” regime, this facility will be based on an exawatt-class laser delivering ultra-short (down to fractions of attosecond) pulses at least 100 times more powerful than any other existing or planned. ELI will strive to be a highly multidisciplinary platform with specialized laser, particle or radiation beam lines dedicated to wide scientific fields, from fundamental ones: atomic, particle, nuclear, gravitational, and cosmology, to societal ones. ELI will for instance benefit in life science, nanotechnology material science, or environment. ELI will finally foster technology transfers, as well as education and training. The ELI preparatory phase aims at establishing all the elements for the start of a successful construction and operation of the facility. It includes the technical studies that define within strict safety guidelines, the laser and its experimental ancillaries characteristics, leading into site selection issues. It examines the legal and governance networking elements that will ensure a stable and smooth operation. It allows steady evaluation of construction and operation costs, as well as decommissioning ones. This three years period will furthermore allow investigating new opportunities opened by the ultra-relativistic regime and consolidating the European
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Neosurance's objective is to propose innovative  short-term insurance policies,proposed to the client a few hours before an event he is going to participate,through an advanced machine learning engine' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Neosurance is a 50/50 joint venture between Neosperience, specialized in Digital Customer Experience, and Digital Tech International, operating in InsurTech sector. The objective of Neosurance is to propose a new insurance product, the ""micro-insurance on the spot"" (""Snap Insurance"").The Snap Insurances are short-term insurance policies, proposed to the client a few hours before an event he is going to participate (a trip, a sport, a concert) through push notifications that he receives on his smartphone, with which it’s possible to finalize the purchase of Snap Insurance in a few minutes from the mobile.Neosurance works with the ambition to create a new insurance market with a completely new and innovative insurance product. Its positioning is unique in the field of ""one-time insurance"": its technology platform is an advanced machine learning engine, based on proprietary algorithm, matches insurance coverages to customer needs in milliseconds.Neosurance also followed a pilot project, installing the SDK of its platform on the app used by a community consisting of more than 500,000 five-a-side soccer players, by connecting the community platform with the Neosurance one and performing the first test by sending push notifications to a defined category of users.Neosurance is applying for Phase 1 of the SME Instrument to develop a feasibility study in order to confirm and define its strategies into its global project, with technical, business and financial objectives. Then Neosurance will apply for Phase 2, to organize a business development program which start selling Snap Insurance first in Europe and then worldwide.Neosurance will bring a sharp breaking in the EU insurance market and, we expect, also on global scale. The company is positioned within the insurance mar
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Exploitation of biotechnology in developing strategies for integrated control of sclerotina stem rot in rapeseed' in the context of a Fourth Framework call.

assistant: **Objectives**

The main objectives are as follows :* To develop an improved method for screening for resistance to stem rot in rapeseed.* To identify new sources of resistance to stem rot among Chinese germplasm.* To introduce new sources of resistance to stem rot into rapeseed varieties using crossing programmes based on both traditional genetic analysis and newly-developed molecular markers for resistance to stem rot.* To identify constitutive and inducible biochemical systems that contribute to resistance to Sclerotinia sclerotiorum.* To identify cultural practices that discourage the development of stem rot epidemics, based on new information on the epidemiology of the pathogen.* To devise strategies for the integrated control of stem rot in China and in Europe that combine improved rapeseed varieties and better cultural practices.Expected OutcomeThe project will develop new, more efficient biotechnology-based methods to strengthen Chinese and European resistance-breeding programmes, and identify improvements to existing cultivation systems that will remove the danger that new resistance is overcome by high pathogen inoculum pressure.The key activities envisaged are :* Testing inoculation methods for screening for resistance to Sclerotinia sclerotiorum on 15-20 locally adapted lines from China.* A diallel cross will be made to obtain F1 progenies for conventional genetic analysis of characteristics of resistance.* Identification of molecular markers for resistance using Bulk Segregant Analysis to identify potential RAPD or AFLP fragments linked to major genes for resistance. These markers will be mapped through existing rapeseed reference maps. Peptide sequence analysis of proteins involved in the expression of resistance will be used to design DNA probes for evaluation as resista
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Optical Mid Infrared Spectrometer' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

All over the world and especially in Europe Gas consumption is increasing, forced by Governments and limitation of crude oil.Distributors facing challenge to guarantee the safety of their grid in urban environments to save human lives. In the same time the costs of energy are increasing and losses of gas during distribution are more and more in the focus of gas distributors.Although various systems for gas detection exists, we are confronted with three main problems:1. gas chromatographs existing are not mobile (lack of real time data) and quiet expensive2. small low cost devices deliver imprecise results because they are not credible in term of temperature compensation and low gas concentration.3. slow response time which contain a high potential of risk in case of upper scale of concentrationTarget of this project is to solve these three main problems and develop a robust mobile device for reasonable costs and response time till less than 2 seconds which identify the four main types of gas (Methane, Propane, Butane, Ethane). This will dramatically reduce labour and gas costs and should be a reasonable argument on the market to purchase this new technologyThe new generation of devices should be based on optical systems which opens new possibilities. The development of this new technology will enable distributors to fulfill their duty to protect a critical infrastructure in urban environment to save human lives and should help to decrease gas losses during distribution process which will help to save valuable resources.The targeted results of phase 1 will be to identify potential suppliers of NDIR sensors and other critical components, to solve existing problems like temperature compensation or sensitivity of gas concentration, explore a business plan and budget and fin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Condition Monitoring and Wide Bandgap Power Electronics - Leading Innovations for the European Energy Sector' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The Horizon CL5 call D3-01-14 asks for a) Condition and Health Monitoring and b) Wide Bandgap and Ultra-Wide Bandgap power electronics for the energy sector with a focus on converters for wind farms and the DC grid. The MoWiLife consortium addresses this call with the most advanced technology. Basis for the four MoWiLife pilots is a 2.3 kV SiC MOSFET, which will be developed by project partner Infineon. It includes a source-gate PiN diode, whose on-state voltage has a strong temperature dependence and can be read out by the gate drive, which will be developed by Rostock University. In addition, self-protection features will be integrated into the SiC chip for robustness and direct water cooling will be realized for higher output power.Two wind energy converter pilots are being realized in MoWiLife by two industrial partners. As one of the technology leaders in wind energy, Vestas – supported by University of Aalborg – will realize a TRL 6 SiC converter with +20% power density and digital-twin Condition and Health Monitoring. The start-up RKL together with Rostock University will develop a TRL 5 wind energy power stack with Condition and Health Monitoring based on online chip temperature and on-state voltage measurement.Solar medium voltage DC collection grids and meshed high voltage transmission grids will play an important role in the future. As third and fourth pilots, a TRL 5 DC-DC converter and a TRL 5 DC circuit breaker including condition monitoring are being developed by the MoWiLife university partners KTH Stockholm and University of Aberdeen.While SiC is today’s Wide Bandgap material for high power applications, ultra-high voltage Ultra-Wide Bandgap semiconductors may allow further efficiency improvements for future HVDC converters. The MoWiLife industrial part
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'SUStainable, innovative and energy-efficient CONcrete, based on the integration of all-waste materials' to be submitted under Seventh Framework.

assistant: **Abstract**

The project aims at developing new technology routes to integrate waste materials in the production cycle of concrete, for both ready-mixed and pre-cast applications, resulting in an innovative light-weight, eco-compatible and cost-effective construction material, made by all-waste raw materials and characterized by low embodied energy and CO2 and by improved ductility and thermal insulation performances. The target of low embodied energy and CO2 will be mainly achieved through working on the binders’ side, while the target of energy efficiency (heat insulation) will be mainly achieved through working on the aggregates side.The use of lightweight recycled aggregates will allow making the target material lightweight and heat-insulating. The focus will be on waste materials that, for quantity, distribution and characteristics are also a social problem but, on the other hand, are available in quantities enough for feeding the concrete industry. On the binder side the aim is the complete replacement of cement by waste materials of high silicon dioxide content, e.g., municipal incinerator ash, ash disposed from coal-fired thermal power plants, and/or in combination with by-products such as ferronickel slag and natural or man-made pozzolans like -silica and metakaolin. Properties regulators will be studied, consisting of highly active  products that will regulate the performance of the binder, taking into account the waste raw materials variability, in order to achieve and stabilize the required properties of final products. The innovative solutions set-up at material level will then be employed to develop innovative concepts of modular building components.The project results, while setting-up a novel low-cost material for producing energy-efficient buildings components, will