RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Assessment of functional immune responses of HIV infected individuals without protective HLA-B alleles', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Infection with the human immunodeficiency virus (HIV) is eventually fatal in the absence of antiretroviral therapy. However, approximately 0.3% of patients have the ability to efficiently control the virus for long periods without treatment (elite controllers). It has been shown that HLA class I restricted CD8+ T cells play a crucial role in this process. There is a strong genetic association between the ability to control the virus and certain alleles of the HLA-B complex (particularly HLA-B*27 and B*57). However, there is also a subset of patients that control HIV in absence of these so-called “protective” alleles, but this mechanism of protection is unclear. Even more strikingly, the recent VISCONTI study showed induction of control in the absence of protective alleles in some patients that received very early therapy (post treatment controllers). Based on these observations, the aim of this study is to determine functional characteristics of CD8+ T cells in elite controllers without protective alleles. T cells and T cell clones of those patients will be functionally phenotyped using in vitro assays and mass cytometry, a very recent technology allowing single cell analysis of up to 37 markers simultaneously. Furthermore, this study will analyze whether elite controllers without protective HLA-B alleles engage additional mechanisms that support functional T cell responses. In particular, the recently described immunoregulatory role of NK cells and the consequences of innate-adaptive crosstalk for immune control of HIV-1 will be assessed.Results from these studies will provide important new insights into the mechanisms that support protective CD8+ T cell responses against HIV, even in absence of protective HLA alleles. The knowledge of how CD8+ T cells achieve efficien
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Narrative media/cultural interaction as means of preventing adolescent violence and political/religious extremism' (2007-2013).

assistant: **Concept**

The ERG-project draws on the results from a MC-EIF-project Media/Trauma-Therapy, pursuing the question of how the psycho-affective and narrative processes of an individual’s mental interaction with media and literary narratives interrelates with her/is life history, and how the person unwittingly implements media interaction in her/is attempts to process her/is personal experience and tackle biographically determined challenges of individual growth, thus gaining soft skills and capacities of resilience and self-management, and developing sustainable forms of interactional and emotional intelligence. Taking the research methods and results from the MC-EIF into account, the ERG-project aims at developing pedagogical interventions and moduls for cultural social work with various risk populations among European adolescents, in particular with those who are prone to violent behaviour and extremist political and religious ideologies. The interventions aim at activating personal memories about self-experienced events which individuals narratively recall in the context of consuming particular items from media and youth cultures; this will be situated in different group settings of social work with endangered adolescents as is conducted by employer NPO which works in regions mostly of East-Germany serving students of different types of public schools as well as imprisoned adolescents and consulting the professionals who work there. The scientific framework is established by resources of qualitative social studies and media-interaction research, therapy- and psycho-trauma studies, narratology as well as culture studies and pedagogy. The target is to develop and evaluate narrational methods which are appropriate and effective with this kind of population and document the results o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'High-Quality Graphene Dispersion in Water for Anti-Corrosion Applications'.

assistant: **Concept**

Corrosion has been a perennial issue of concern for the metal industries, especially steel. Non-ferrous metal-based coatings are well known pre-treatments but due to environmental concerns and legislations (i.e. REACH), their use has been drastically restricted. The industrial community, pushed by these legislations, has been long demanding an economically viable and eco-friendly pre-treatment coating alternative, without having to compromise on the durability and corrosion performance of the overall coating system. With its outstanding properties, graphene appears as a promising alternative for non-ferrous metals in the coating market, having the potential to provide corrosion protection even when applied in thicknesses of a few nanometers. But the new graphene industry faces still crucial challenges, mainly production cost, quality and consistency. Our company, Carbon Waters, has developed a unique, patented, extremely controllable technique of chemical super-exfoliation to produce GRAPHENE WATER, which consists on dispersing few-layer graphene in water, without using additives and at a competitive cost. Its advantages face to competitors are unprecedented: our high-quality graphene dispersion allows for a stabilized, safe, homogeneous effect on the treated surfaces, ensuring optimum performance. Within this project, we aim to bring our current developments on graphene based anti-corrosive coatings to industrial applications and market readiness (TRL9). With GRAPHENE WATER, Carbon Waters will provide to the EU metal industries an eco-friendly alternative for surface protection, allowing them to commit with the regulatory framework without jeopardizing cost-competitiveness. Exploiting this technology, we aim to become a reference in the field of carbon-based nanomateri
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Secondary photochemical reactions and technologies for active remote sensing of nocturnal atmosphere' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

The key objective of the “NOCTURNAL ATMOSPHERE” project is to carry out the coordinated transfer of knowledge measures between participating teams in the EU, in the Ukraine and Russia with the aim of restoring and strengthening scientific collaboration and of developing new partnerships for long lasting synergy, to enhance the level of scientific excellence of participating early stage and experienced researchers and technicians. The transfer of knowledge and achievement of intellectual “critical mass” will occur through performing joint theoretical exercises and laboratory research in the important and growing field of secondary photochemical reactions in the Earth’s nocturnal atmosphere and in development breakthroughs of active remote sensing technologies for night-time cartography of the Earth troposphere and stratosphere. The challenge is to create a unique instrument for ranging sensors on satellite, crossing night-time sky segment, with a combined laser&white light beam from the Earth. The project participants have high scientific qualification and relevant theoretical and experimental experience and specific technical skills to achieve progress in research on the nocturnal atmosphere. The joint efforts will work synergistically to amplify their knowledge and skills. The staff exchange and secondments will include both a team doing research on specific work packages and a transfer of knowledge component consisting of seminars, workshops and summer schools which will ensure effective dissemination of results and foster interactions amongst the young researchers and PhD students. They will be mentored by and intensively exposed to a culture of international collaborative research.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Innovative cost-effective technology for maximizing aquatic biomass-based molecules for food, feed and cosmetic applications' to be submitted under Horizon 2020.

assistant: **Abstract**

EU society needs new sustainable biobased feedstock in order to meet the growing population needs and to reduce the dependence on fossil fuels. In terms of potential market requirements in EU, the food and fuel demand is mainly covered by foreign import, achieving the 68% of total proteins supply. Aquatic feedstock can be a solution to these necessities, however, European algae feedstock market is still facing immature production technologies, and which are not specifically designed for algae biorefinery. The overall objective of BIOSEA is the development and validation of innovative, competitive and cost-effective upstream and downstream processes for the cultivation of 2 microalgae (Spirulina platensis and Isochrysis galbana), and 2 macroalgae (Ulva intestinalis and Saccharina latissima) to produce and extract at least 6 high value active principles at low cost (up to 55% less than with current processes) to be used in food, feed and cosmetic/personal care as high-added value products. For achieving this objective, BIOSEA consortium consists of specialists in specific area/s or discipline/s involved in the project (IGV, AT SEA and CTAQUA in Biological Sciences and Biotechnology; VITO and FEYECON in Chemical Science and Engineering; CNTA, BIOPOLIS, DIBAQ, SORIA NATURAL and CPCFEED in Food/Feed Technology; VLCI and HENKEL in Cosmetic Science; AITEX in Materials Science and TABU in Environmental Science). The total budget of BIOSEA is up to €4,633,447, so it is totally aligned with the range considered in the topic. It can be added that the industrial contribution will be up to €2,611,321, representing a percentage of 44% of the total budget and indicating the strong weight and involvement of the industry in the proposal.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'A Gaia and Herschel Study of the Density Distribution and Evolution of Young Massive Star Clusters' to be submitted under Horizon 2020.

assistant: **Abstract**

We propose to use a combination of data from the ESA space missions GAIA and Herschel, alongside other satellite and European-led ground-based observations, to map the density distribution of star formation regions.    This will allow us to identify the mechanisms that underlie both how massive stars themselves form, but more fundamentally, how their natal clusters evolve around them.  Our work will underpin studies of how all galaxies evolve.  The combination of the two ESA missions will allow us to study clusters and associations of stars when they are very young (much less than 1 Myr old), when the structures we see are a better match to the initial conditions.  No one has attempted such a project before as the required datasets were not available. The novel data and complexity of the combined datasets require the development of new analysis and visualization tools. In particular we will statistically compare hybrid large scale N-body + SPH models with the combined 6-dimensional Gaia plus Herschel and gas kinematical data. Our goals therefore are structured to develop new techniques that we will initially test on simulations. We will follow this with tests on observational data of slightly older clusters (about 1Myr old).  We will then apply the tested methodologies to the very youngest clusters. This will address our final goal of cracking the problem of how the most massive stars and clusters form.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'An Affordable, miniaturisEd, clOud-connected system powered by deep Learning algorithms for comprehensive air qUality measurements based on highly integrated mid-IR photonic' under Horizon 2020.

assistant: **Concept**

AEOLUS, leveraging on the experience of its partners on novel photonic components (e.g. broadband thermal emitter, graphene photodetector), will demonstrate in an operational environment (TRL 7) an affordable, miniaturised, multi-gas (10 - 15 gases) sensor based on highly integrated photonic chips in the mid-IR (3 μm - 10 μm). AEOLUS sensors will be cloud connected, deployed in an existing IoT testbed, while the plethora of data acquired will be used to develop deep learning algorithms for chemometric analysis.AEOLUS sensing system will demonstrate the calculation and accurate prediction of indoor and outdoor air quality, greenhouse gases concentration, and toxic gas leakages detection. The sensing system will provide many functionalities for the end-user such as real-time alerts, notifications, visualized reports and overlays while it will allow taking automatic actions where they are needed. AEOLUS will also demonstrate how user engagement can be promoted through its system, employing gamification concepts and incentivise the end users. AEOLUS targets for a cheap portable sensor, tested for its interoperability, with many functionalities and quality of life services, targeting a very wide range of applications to ensure its widespread deployment. The proliferation of the AEOLUS sensor in the community acts in an exponential manner (leveraging Big Data techniques and Deep Learning algorithms), further enhancing the system’s accuracy and speed. AEOLUS sensing system is completely in line with its industrial partners' roadmaps and exploitation plans and it is foreseen to have a product in the market 0-2 years from the end of the project.Ultimately, the acquired data and analysis will be made available to policy-makers and stakeholders, so that AEOLUS has a far-reaching i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Safe Food for Infants in the EU and China'.

assistant: **Concept**

SAFFI targets food for EU’s 15 million and China’s 45 million children under the age of three. It aims at developing an integrated approach to enhance the identification, assessment, detection and mitigation of safety risks raised by microbial and chemical hazards all along EU and China infant food chains. SAFFI will benchmark the main safety risks through an extensive hazard identification system based on multiple data sources and a risk ranking procedure. It will also develop procedures to enhance top-down and bottom-up hazard control by combining management options with a panel of technologies for the detection and mitigation of priority hazards. SAFFI will discover unexpected contaminants by predictive toxicology and improve risk-based food safety management of biohazards by omics and predictive microbiology. SAFFI will co-develop with and deliver to stakeholders a decision-support system (DSS) to enhance safety control all along the food chain. This DSS will integrate the databases, procedures and methods described above and will be a framework for a generic DSS dedicated to other food. This overall methodology will be implemented in two complementary European and Chinese mirror projects and exemplified for each, with four case studies that were selected to cover priority hazards, main ingredients, processes and control steps of the infant food chain. Resulting databases, tools and procedures will be shared, cross-validated, concatenated, benchmarked and finally harmonized for further use in the EU and China. SAFFI will also set up training and knowledge transfer activities to foster EU-China harmonization of good practices, regulations, standards and technologies, and will cluster with other projects under the EU-China FAB Flagship initiative for continuous upgrad
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Unveiling the role of histone marks in metabolic memory storage and transmission.' (HISTORABLE).

assistant: **Concept**

Type 2 diabetes (T2D) is a multifactorial disease affecting over 450 million people in Europe alone, amounting to the burden of life-threatening diseases and worsening quality of life. Skeletal muscle is affected early in T2D and contributes to the fast decline of whole-body glucose homeostasis, which is called insulin resistance. Interestingly, even when isolated from the body and cultured in a laboratory in non-diabetogenic conditions, the skeletal muscle cells do not lose the characteristics of the donor, i.e., the cells remain insulin resistant, indicating the existence of a cell-autonomous mechanism that retains the metabolic memory across generations of cells. Nonetheless, such a mechanism remains elusive. Accumulating evidence suggests a potential role of histone post-translational modifications as essential vectors of inheritable information, but it is still a matter of intense debate. In this project, to address this question and understand the pathology of T2D, we will trace a comprehensive genome-wide map of histone post-translational modifications induced by T2D in human primary skeletal muscle cells and investigate whether these histone marks can store and transmit information about the metabolic phenotype from the donor to the next generation of cells. Targeted studies using pharmacological and genetic interventions will then address the role of histone modifying enzymes in metabolic memory transmission. The outcomes could lead to a novel understanding of a broader system of cellular memory storage and transmission. By characterizing the disturbances caused by diabetes in the epigenome using state-of-the-art techniques and multidisciplinary approaches, we could pave the way for innovative clinical interventions addressing a critical global health challenge
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Development of 3-D eye tracking device for safer driving and more efficient web page production (DRIVESAFE)' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

An Eye Tracking Device (ETD) facilitates the comprehensive measurement of eye movements (horizontal, vertical and torsional): it provides the basis for many types of vestibulo-oculomotor and visual research works, and can be adapted to locate gaze positions (i.e. the position on a computer. screen or through a vehicle windshield where the eyes are looking at). A consortium of six SMEs active in the field of data acquisition on board vehicles (ONE-TOO) and in the field of advertisement optimization on Web pages (AREA17, INCORDIA, PLAN_B MEDIA, APPSS, MULTIMEDIA) have joined to develop anew, portable 3-D ETD system which is able to perform eye and gaze tracking, at very high sampling rates and within difficult environments. They rely on a group of SME (Kayser Threde, MEDIASCORE) and a Research organisation (INRIA) in order to develop a prototype ETD with features and benefits much beyond what is currently available in order to answer questions such as How are the eyes behaving when the hypo vigiiance state of a road vehicle driver is observed? How are the eyes behaving in front of complex Web page screens presenting myriads of data to Web surfers This research project improves the NASA implemented eye tracking solution, from KA YSERTREDDE., and should implement some of the latest software algorithms developed by MEDIASCORE for gaze measurement. This project is in support of Improved innovation in service companies (In the car industry where there is a need to develop at a European level an understanding of driver's hypo vigilance to make cars, in the marketing and communication industry where there is already a considerable activity in the impact measurement of Web pages on consumption behaviour). This project supports also trans national cooperation, where a space-based