RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Uncovering the Diversity of Cell-Cell Interactions that Impact Cell Fates' (CELLMATES).

assistant: **Innovation**

Multicellular life relies on coordinated physical interactions and communication between cells. In these interactions, cells exchange information that determines their fate, physiological state and behavior. The substantial transcriptional heterogeneity that is evident even among cells considered the same type, however, raises questions about exactly which temporal and spatial interactions regulate development and homeostasis. During development, for instance, multipotent neural crest cells migrate along different pathways in which they encounter microenvironments that are thought to instruct their migration and fate choices. To ultimately reveal how cell communication shapes cell identities and cellular decisions, we need to know the transcriptional state of a cell and that of its neighbors. Current technologies either sequence single cells at high transcriptional resolution or localize cells in their spatial context but without capturing their precise transcriptional configuration. To overcome these limitations, we will establish a novel approach that provides high-resolution transcriptomic information on cellular microenvironments. We will use this approach to uncover the interactions and communication codes that neural crest cells are exposed to along their developmental path. In addition, we will develop strategies to systematically identify cell-cell interactions likely to determine migration and cell fate decisions, and elucidate their functional role in the developing embryo. Our overall goal is to uncover how the diversity of cell interactions orchestrates the development of a complex cell lineage. This approach and the insights obtained here will provide a foundation for studying how cells interact in other systems such as human tissues, and how these interact
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Biodegradation of Toxic Organic Compounds in Waste Water and Accumu lation of Heavy Metals' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Foreseen ResultsAll results will be tested and critically discussed in the laboratories of all partners participated in this proposal and in field experiments for a practical simulation of the processes developed.The proposal has the intention to develop new technologies for processes with a high degradation rate for some toxic organic compounds, e.g. phenols and their derivatives, halogenated or not halogenated hydrocarbons as well as with the possibility of accumulation of heavy metals by such degradation processes.The contamination of the environment needs effective technologies with a high profitableness and efficiency with an applicability not only in the Eastern and Central parts of Europe but also in other parts of the world, too. In the network of our research the partners will solve the following problems:Isolation, characterization of new strains isolated from contaminated sites and the preservation of active strainsTo develop new technologies and materials for a stable and inexpensive immobilization of the most active strainsThe most interesting classes of compounds are phenols and phenolics, hydrocarbons (halogenated and non-halogenated)To develop technologies for a simultaneous degradation of such compounds and accumulation of heavy metals introduced in a similar way to the environmentApplication of the microbe-plant ecosystem on the roots of plants for both types of processes, the degradation and metal accumulationInvestigation on the specific reactor constructionsInvestigations on the kinetics of the processes for a better understanding as a base for further developments of new processesAt the end of the project there will be also a small sewage treatment plant using the plant-microbe ecosystem with the orientation to small equipments for villages and oth
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The ecological consequences of chemotypic variation of damage-induced volatile organic compounds in sagebrush (Artemisia tridentata)' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Plants have evolved an impressive defense system to combat herbivores. These defenses include morphological structures like spines and secondary metabolites that have toxic, repellent, or antinutritional effects on consumers. Many plant defenses are constitutively expressed, but some are induced in response to herbivore damage. Damaged plants emit volatile organic compounds (VOCs) into the environment that may induce defenses in adjacent, undamaged tissue or may be eavesdropped by neighboring plants, enabling them to prime their own resistance response prior to attack. While once controversial, this plant-plant communication resulting in a VOC-induced phenotypic response that reduces damage from attacking herbivores has been demonstrated in over 50 species. Recently, researchers have found distinguishing VOC blends among sagebrush (Artemisia tridentata) referred to as chemotypes. Field experiments demonstrated that communication between A. tridentata plants of the same chemotype resulted in less damage by herbivores compared to that between plants of different chemotypes. Chemotypes were also found to be highly heritable. This is consistent with the hypothesis that volatile communication evolved as a within-plant warning mechanism due to limited vascular signaling. Because emitted volatile cues become available to potential competitors of the same or different species, selection for cues that are more private would likely be of greater benefit to the emitter.  At the time of this study, only 2 A. tridentata chemotypes had been identified. More recent work has found an additional 6 chemotypes. Here we propose to rigorously test the ecological consequences of chemotypic variation and the processes that maintain it. Through synergistic efforts combining my expertise in fie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Power System Wide-area GPS Synchronized Monitoring with Phasor Measurements and Low-Frequency Oscillation Mitigation Analysis' to be submitted under Seventh Framework.

assistant: **Abstract**

Electric power is essential to modern society. Economic prosperity, national security, and standard of living depend on reliable electric power systems. But increases in open access transactions, heavy loading, weak connections, hidden failure in protection, and other unexpected events may cause the system to lose balance and even lead to catastrophic failures. To compete in the new global market, European industry must have a more sustainable energy system and increase the efficiency, flexibility, safety, reliability and quality of the European electricity systems and networks. Thus, there is the need for a new action to bring Europe up to date with the state-of-the-art power system measurement, control and protection ideas, methodologies, tools and techniques. As a new class of measurement, synchronized phasor measurements greatly elevate the availability as well as the quality of data and information useful to improve system monitoring, protection, control, and operation of the increasingly stressed power systems. The project proposed here consists of syncronized phase measurement and the study of low-frequency oscillation mitigation. The major objective of this project is to enhance the available knowledge and tools that will promote a better system-wide monitoring accuracy and devolop new control and reliability tools for electricity systems through the applications of synchronized phasor measurements. Therefore, the project which is of considerable importance in contemporary electrical science as well as for numerous technological applications will focus on the specific research topics as following: 1) Study on the method of optimal PMU placement; 2) An alternative for including phasor measurements in state estimators; 3) Synchronized frequency measurements under
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Flexible Microchip Manufacturing for New Industries in Europe' (FLEMANIE).

assistant: **Innovation**

The manufacturing of microelectronic chips represents one of the most advanced industrial activities, ironically though, it is also one of the most standardized and commoditized industries. Small companies developing new applications need small volumes of non-standard chips, often utilizing special materials, however major foundries require enormous production volumes since the price of each chip is usually very low. Small companies thus struggle to find sources for their chips, fatally increasing the time to market of their new products. Summa Semiconductor Ltd is a Finnish microelectronics foundry specializing in flexible and scalable processing of semiconductor chips, promoting FLEMANIE – Flexible Microchip Manufacturing for New Industries in Europe - as a new production model: ensuring fast and flexible manufacturing of products, no matter the quantity, working with an “asset light model”, ensuring accurate simulation of production processes. This Phase I would grant us the resources to dedicate time and effort on expanding our collaborator network testing the concept with potential users, validating our process module simulation based manufacturing technology with potential users together with assessing the market, technical and business feasibility of our solution. At the current stage, our company can serve a limited number of small companies (based on needs more than geographical location). However, our goal is to develop the simulation based manufacturing technology – possibly thanks to a Phase 2 project - to achieve a significant competitive advantage for both European industries and worldwide.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'BROWNFIELD Decontamination In Southern Europe. Preparing PCP to R+D for efficient, cost effective and innovative solutions for brownfields decontamination' (BRODISE), addressing dissemination and exploitation.

assistant: **Impact**

Public procurement represents +/-19% of the EU’s GDP. Historically a small and slower uptake of innovations has been witnessed along with the fragmentation of publ demand.. PE represents a fundamental driver of innovation and competitiveness.Urban regeneration conducted by Bilbao confirms that the development of mixed formulas publ-priv for projects of mutual interest entails higher quality, effectiveness+efficiency in the management of publ services. Innovation procurement of products and services can (i) be used to deliver societal objectives requiring new solutions not available on the market or too expensive (ii) solve problems related the commercialization of innovative solution (iii) improve quality+efficiency of publ services with  better value 4 $. It is clearly set by the BRODISE project. Objectives:Mobilize publ+priv purchasers+cities networks of cities in SD, , to understand in-depth the technology state of the art and the innovation gap to be addressed by significant R&D,Structure+design a pcp initiative, leveraging the complementarity of the partners for bringing together the demand so create a critical mass for acquire cost-effective solutions, whilst creating new jobs and opportunities for business growth in Europe, specially SMEs. The driver is essentially economic. A complex challenge-based approach has been assumed by the consortium to:Confirm and describe a real technological demanding problem that impact negatively on the PE and on quality of life for all; Avoid the hyper-fragmentation of PP, pre-determine the condition for the development of new EU standard; Predetermine a  competitive market, also enabling and preparing the participation of new players, Enable knowledge sharing.At the end the procurers will be able to lunch PCP and an earlier reali
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'The malaria chemical atlas: Revealing the parasite-host functional interactome'.

assistant: **Innovation**

Malaria is the most life-threatening parasitic disease in humans. Invasion of the malaria parasite, Plasmodium falciparum (Pf), into the blood circulation rewires the harmonious networking between the resident cells. Until recently, Pf was not thought to be able to communicate when nested within infected human red blood cells (RBCs). However, we and others have laid the foundations of Pf communication via extracellular vesicles. We now hypothesize that in order to survive in the hostile host environment, Pf secretes chemical inducers (e.g., metabolites, peptides) to actively coordinate life decisions as a group and to control the surrounding host cells. Remarkably, we obtained proof-of-principle preliminary results in the form of an isolated, active chemical fraction that inhibits Pf population growth in a density-dependent manner.Our overarching goal in MalChemAtlas is to expose this yet-to-be-revealed mode of communication in malaria:  cell-to-cell chemical signaling. We will combine analytic chemical, biophysical and omics technologies with machine-learning approaches to comprehensively reveal and characterize the functional chemicals that: I) facilitate parasite density, growth and sexual development (parasite-parasite signaling), II) dictate parasite crosstalk with circulating host immune cells and naïve RBCs (parasite-host communication), and III) affect downstream signaling cascades between the host’s innate and adaptive immunity (host-host communication). In this effort, we will leverage our extensive (HPLC-based) analytical fractionation pipeline, combined with NMR and metabolomics analyses, for identifying malaria-secreted autoinducers.Our preliminary findings demonstrate the potential of our basic research to be applied to the translational level of intervent
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Systems approach to environmentally acceptable farming' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

Problems to be solvedRising concern about agricultural non-point water pollution has led to propose many regulatory measures. Agri-environmental programmes have been implemented in the different EU Member States according to the Commission regulation 2078/92. Best management practices (BMPs), one of the most popular tools, have rarely been assessed in a fully satisfying way yet. This project aims at providing planners with a grid that would allow a comparison between BMPs in terms of environmental efficiency, economic cost and potential acceptability by farmers.Expected results should contribute to help Member States choosing the most appropriate measures and ways for an efficient implementation of BMPs, with the support of scientifically validated technical and economic recommendations, thus contributing to various EU policies such as CAP, Instruction 91/676/CEE, Instruction 80/778/CEE, and more generally the European water policy.Scientific objectives and approachA comparison between different existing or simulated BMPs will be carried out through a cost/effectiveness assessment along with the study of their acceptability by farmers. Effectiveness will be assessed as the evolution of water quality resulting from BMPs' implementation in experimental watersheds. Particular efforts will be carried out to improve BMPs representation in hydrological models, as they can take various forms (landscape structures, agronomic recommendations). Spatial modelling, at various scales, will be used to define critical areas where efforts should be concentrated. As for costs, efforts will concern the evaluation of both direct and indirect costs induced by BMPs implementation. When studying diffuse pollution, individual contributions and de-pollution costs are not known and have to be a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Contrast by Quadrupole Enhanced Relaxation' in the context of a Horizon 2020 call.

assistant: **Objectives**

The ageing society and demographic change is one of the major challenges which Europe is facing now, and even more so in the future. Mastering this challenge requires radically new diagnostic and therapeutic treatments as key factors in achieving the healthy well-being of European citizens. Molecular imaging (MI) plays a pivotal role in diagnosis, understanding of disease and in the development of effective treatments. CONQUER will explore a fundamentally new contrast mechanism with the potential to push magnetic resonance imaging (MRI) far beyond its limits towards a powerful MI modality. This will be achieved by exploiting the cross relaxation between 1H and large quadrupolar nuclei (QN) for contrast agent (CA) design. The main objective is to synthesize bio-compatible QN compounds and nano-particles (NPs), high efficiency and manifold degrees of freedom in the design of smart properties, such as the ability to switch the contrast on and off by changing the magnetic field or chemical binding (e.g. targeting). The NPs will be tailored based on quantum-mechanical simulations. Sensitivity and contrast switching will be demonstrated with MRI in cell cultures. This highly interdisciplinary project combines expertise in quantum physics, chemical and biomedical engineering, material characterisation as well as nanotoxicology. Today, European scientists and companies are already leading global players in CA development. CONQUER will significantly fertilise this field and lay the scientific foundations for a new technology by providing theoretical groundwork, synthesis guidelines, imaging instrumentation and toxicological references. These results will be actively transferred to academia and industry as well in order to strengthen European competitiveness. The combination of a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Proving Operations of Drones with Initial UTM Management' (PODIUM).

assistant: **Innovation**

The PODIUM project comprises four complementary, large scale demonstrations, taking place in  Denmark, France and the Netherlands where more than 185 drone flights will be conducted. Its partners’ quick wins integrated UTM solution will be demonstrated in a broad range of realistic operational conditions of drone operations (VLOS and BVLOS) in VLL airspace (controlled & uncontrolled airspace; urban, rural and in the vicinity of airports) interacting with manned traffic. Each of its four sites has its own specificities (e.g. routine day to day operations, emphasis on UTM/ATM communication, normal/abnormal conditions).The demonstrations will notably enable its safe and secure use by various categories of users (e.g. authorities, drone operations, drone pilots) and for many types of drone operations (e.g. electricity line inspection, emergency services). Together the four sites demonstrations ensure a comprehensive and extensive demonstration of the full potential and technology readiness level of the PODIUM UTM functionalities (from Before-flight to Post-flight with a special focus on in-flight dynamic geo-fencing). PODIUM is a U-Space compliant demonstration.Under EUROCONTROL leadership, PODIUM consortium comprises 10 members,17 linked third parties and 4 sub-contractors, including many in-kind contributions. By bringing together drone actors (UTM provider, drone operators, drone trackers manufacturers), ATM actors (ANSPs, ATM system integrator & others) and infrastructure providers (drone demonstrations centers, telecommunication network) supported by their local authorities in its Advisory Board, PODIUM project will naturally improve the links between the drone and the ATM communities therefore contributing to a safer integration of drone operation in the European airs