RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Reducing the impact of major environmental challenges on mental health' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The environMENTAL project will investigate how some of the greatest global environmental challenges, climate change, urbanisation, and psychosocial stress caused by the COVID-19-pandemic affect mental health over the lifespan. It will identify their underlying molecular mechanisms and develop preventions and early interventions. Leveraging cohort data of over 1.5 million European citizens and patients enriched with deep phenotyping data from large scale behavioural neuroimaging cohorts, we will identify brain mechanisms related to environmental adversity underlying symptoms of depression, anxiety, stress and substance abuse. By linking population and patient data via geo-location to spatiotemporal environmental data derived from remote sensing satellites, climate models, regional-socioeconomic data and digital health applications, our interdisciplinary team will develop a neurocognitive model of multimodal environmental signatures related to transdiagnostic symptom groups that are characterised by shared brain mechanisms. We will uncover the molecular basis underlying these mechanisms using multi-modal -omics analyses, brain organoids and virtual brain simulations, thus providing an integrated perspective for each individual across the lifespan and spectrum of functioning. The insight gained will be applied to developing risk biomarkers and stratification markers. We will then screen for pharmacological compounds targeting the molecular mechanisms discovered. We will also reduce symptom development and progression using virtual reality interventions based on the adverse environmental features - developed in close collaboration with stakeholders. Overall, this project will lead to objective biomarkers and evidence-based pharmacologic and VR-based interventions that will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Utilizing the potential of NANOSATellites for the implementation of European Space Policy and space innovation' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Current project has focused on investigating opportunities, how nanosatellites could be used to support the implementation of European Space Policy. Nanosatellites serve to be cost-effective science and technology platform to make sustainable contribution to a roadmap for space and innovation in Europe, which includes realizing a potential of new and innovative space applications and stimulating an evolvement of new business models for space missions. In that regard, the NANOSAT project brings together partners from nanosatellite development network in Europe to create the opportunities for continuous and sustainable collaboration between nanosatellite players, furthering the advancement of nanosatellite platform, development of innovative space applications and sharing the knowledge base with each other.The main objective of the NANOSAT project is to contribute to a roadmap for space and innovation in Europe through studies and events in support of highly capable small satellites and thereby innovative space applications and new business models for space missions in Europe. In order to reach to desired impact, the NANOSAT project has defined the following specific objectives:•Consolidate main actors in European nanosatellites landscape by creating functional network, showcasing best practices and potential markets to serve the objectives of European Space Policy;•Demonstrate nanosatellites potential in Europe by proposing innovative services which will complement and create synergy with GMES services by addressing information needs faster and more flexibly;•Draw “proof of concept” missions that will realize the ability of nanosatellites to perform missions like communications and Earth observation in support of European Space Policy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Energy-efficient, community-based water- and wastewater-treatment systems for deployment in India' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The overall aim of ECO-India is to design and develop innovative cost-effective solutions for community- based water- and wastewater- treatment systems. These systems will be deployed at pilot sites in arsenic-affected water-stressed regions in India. The two consortia, Indian (DST) and European (FP7), will establish pilot schemes for•catchment area and reservoir management•surface water supply schemes•arsenic removal (including monitoring using UFZ’s field-tested Arsolux arsenic sensor)•disinfection treatment for potable water based on Trustwater’s EC-certified mixed-oxidant generation systems.•online monitoring of water quality•water distribution network, together with online/offline water quality monitoring programmes•sewerage and wastewater treatment.In addition, prototype energy-efficient modules for water deionisation and heavy metal removal will be developed. A feasibility study will be performed to assess the potential for energy harvesting from sludge.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Analysis of the expression pattern and target genes of constans, a putative plant transcription factor that promotes flowering' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

Research objectives and content The CONSTANS gene of Arabidopsis is required to promote flowering in response to photoperiod. The gene was recently cloned and shown to encode a protein that is very likely to act as a transcription factor. To study how the CONSTANS protein regulates flowering time, I propose to analyse its pattern of expression and to identify its target genes. Transgenic plants carrying fusions between the CONSTANS promoter and reporter genes will be used to determine the expression pattern of CONSTANS in different environmental conditions and at different developmental stages. The identification of genes regulated by CONSTANS will be carried out by differential display, using transgenic plants in which the activity of CONSTANS can be regulated by the addition of a glucocorticoid. Training content (objective, benefit and expected impact) This project will extend my experience in plant molecular biology and will provide me with training in plant genetics and in the study of gene interactions in the same genetic pathway to understand their combined impact on flowering. Links with industry / industrial relevance (22) This project is related to an EC-funded programme, 'Genetic and Molecular Control of the Transition to Flowering'. Dr. Coupland's group, other European laboratories and industrial laboratories are involved in this programme.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Strategic Conversation' to be submitted under Seventh Framework.

assistant: **Abstract**

I propose a five year interdisciplinary project that will develop a new, formal and robust model of conversation, drawing from ideas in linguistics, philosophy, computer science and economics.  The project brings a state of the art, linguistic theory of discourse interpretation together with a sophisticated view of agent interaction and strategic decision making.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Seeing the invisible: Light-based 3D imaging of opaque nanostructures' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Nanostructures drive the world around us. Every modern electronic device contains integrated circuits and nano-electronics to provide its functionality. Advances in nanotechnology directly impact society by enabling smartphones, autonomous devices, the internet of things, data storage, and essentially all forms of advanced technology.  Fabricating such nanostructures crucially depends on having the tools to make them visible without destroying them. Modern nanodevices often have complex three-dimensional architectures with small features in all dimensions. While imaging methods that achieve nanometer-scale resolution exist, there are currently no compact tools that can look inside 3D nanostructures made out of metals and semiconductors without damaging their delicate internal structure.  I will address this challenge by developing compact tools to image 3D nanostructures in a non-invasive way. Even though most nanostructures are completely opaque to visible light, I will develop light-based methods, combined with computational imaging techniques developed in my previous ERC project, to look inside them with unprecedented resolution and contrast. Light-based imaging is unparalleled in speed and versatility, and allows contact-free detection. My proposal is to: 1) Use compact laser-produced soft-X-ray sources to image nanostructures with high 3D resolution and element-sensitive contrast; 2) Use laser-induced ultrasound pulses to image complex 3D nanostructures, even through strongly absorbing materials; 3) Employ computational imaging methods to reconstruct high-resolution 3D object images from the resulting complex diffraction signals. I will forge a coordinated research program to bring these concepts to reality.   This program provides exciting prospects for fundamenta
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Isolation of expressed sequences by exon trapping and cdna selection using p1 phage clones from chromosomal region 13q12-q13' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

To identify and isolate the putative BRCA 2 gene P1/P1 derived artificial chromosome (PAC) clones from human chromosome 13ql2-ql3 will be searched for transcribed sequences. By P1/PAC clones large DNA fragments of about 100 kb can be cloned in E. coli where pure DNA can be prepared easily, making them more suitable for exon trapping and cDNA selection than YAC inserts, which often can only poorly separated from yeast host chromosomes. An improved exon trapping protocol suited to analyze genomic fragments from 30 kb-3 Mb will be applied to DNA from single or pooled P1/PAC clones. Isolated exons will be sequenced and used as expressed sequence tags (ESTs) to screen cDNA libraries. P1/PAC DNA will also be used for cDNA selection using pooled cDNA libraries tagged with different linkers for hybridization. Use of exon trapping products for cDNA selection could lead to the identification of low abundant transcripts.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Structure engineering of emulsions by micro-machined elongational flow processing'.

assistant: **Objectives**

The results of this project lead to new technology for production of emulsion-based food products with innovative functional properties and improved product quality. Healthier products can be produced such as low fat products and functional foods with new encapsulation techniques for the functional ingredients. This project provides a unique structure-engineering concept, where knowledge of structure formation is combined with process design and completely new concepts for micro-machine processing. New functionality will be generated by structures of active particles with designed size and shape. The project is multidisciplinary and bridges the gap between fundamental knowledge about structure formation and equipment available to produce products based on this technology. The objectives will be achieved by work on particle structuring, interfacial behaviour, fluid dynamics, process design, equipment development and particle functionality.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Vascular remodelling and miRNA therapeutics' (VASCMIR), addressing dissemination and exploitation.

assistant: **Impact**

The central hypothesis of VascmiR is that microRNAs (miRs) fundamentally control pathological remodelling of the vasculature. The complexity of vascular bed heterogeneity and subsequent response to injury, the potential importance of miRNA in vascular pathology and the paucity in knowledge relating to many facets of miRNA function in the vessel wall including target pathways, mechanistic features of miRNA-mediated cell:cell communication mediated by miRNA export and uptake etc. provides an excellent opportunity for groundbreaking basic and translational research in the field. VascmiR will envelop these concepts in a broad, cutting edge portfolio of high risk and in-depth studies that encompass fundamental research, mouse genetics to create novel models and miR intervention studies in small and large animal models coupled with targeted miRNA therapeutics. Collective synergy by assessing pulmonary as well as peripheral venous and arterial pathological vascular remodelling models of disease under a single funding mechanism will afford substantial scientific advancement. VascmiR will go beyond current state-of-the-art and create new knowledge of miRNA in vascular pathologies, all of which have important unmet clinical need. VascmiR will streamline fundamental new opportunities for targeted miRNA-based therapeutics to improve human health in cardiovascular setting. I envisage that a co-ordinated, multifaceted and integrative programme in these vascular pathology settings to better understand the mechanistic role of miRNA in vascular remodelling will have a major impact on the field, leading to early translation of advanced miRNA therapeutics in the vasculature.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'CIDNP study of photo-chemically generated short-lived radical intermediates of biologically important molecules' (2002-2006) targeting Sixth Framework.

assistant: **Abstract**

The project is aimed at the application and further development of a novel non-destructive NMR method of high sensitivity, chemical selectivity, and high spectral resolution. The method is based on chemically induced dynamic nuclear polarization (CIDNP) f or studying the structure and dynamic processes of biological macromolecules at physiological conditions. We propose to utilize the nuclear spin polarization that is formed in the reversible light-induced radical reactions of dye markers with proteins and nucleic acids and their structural subunits (amino acids, peptides, nucleotides, oligonucleotides) in aqueous solution and to expand the application of the method to similar processes in the solid state.The research methodology includes application of three types of CIDNP experiments:(i) with time-resolution,(ii) with magnetic field variation by field-cycling, and(iii) with resonant pumping of electronic spin transitions for NMR detection of EPR spectra of spin correlated radicals pairs in combination with field-cycling.The project has an interdisciplinary character and includes biological, photochemical, and physical approaches. The research activities are associated with the following:1. The study of photochemical reactions involving proteins and protein-related molecules will create a reliable basis for studying proteins using the CIDNP technique, and will contribute to the knowledge of photochemistry of biopolymers.2. The investigation of native partially folded and denatured states of proteins, as well as the study of the processes of denaturation and folding will be compared with the theoretical modelling of protein dynamics.3. Development and application of MAS-NMR detection of time evolution and field dependence of nuclear polarization in proteins in solid sta
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Aqueous Power Batteries to enable the Future Energy System' under Horizon Europe.

assistant: **Concept**

We are introducing to the market a new class of aqueous high-power-density, highly durable batteries produced without using any critical raw materials or toxic solvents, using low-cost manufacturing methods with ultra-low carbon footprint. Our breakthrough batteries are built using abundant, off-the-shelf raw materials bearing no geopolitical risks, such as common inorganic salts and carbon powders. This enables a resilient EU-based supply chain. The unique engineering design we employ in making battery cells allows for safe and technologically simple recycling, which further contributes to their sustainable life cycle, supporting the circular economy. The application area of our battery technology is the so-called fast energy storage (buffering of power) that is needed to facilitate effective integration of the long-term energy storage, incl. Power-2-X technologies. Fast energy storage solves the problem of energy grid flexibility to enable transition to the 100% renewables-based economy as it addresses the problem of intermittency of energy supply by fast leveling of temporal mismatches between generation and demand at sub-second-to-minutes intervals.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'An equipment for responsive adsorption assessment of dynamic adsorbents in liquid phase' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Liquid phase adsorption technology is crucial in industrial sectors focused on the separation, purification, or extraction of liquids or dissolved species such as petrochemical, water treatment, and pharmacologic industries. However, the characterization of the adsorption capacity of sorbents towards adsorptives in the liquid phase is still complex. Commonly used procedures for liquid phase adsorption characterization are tedious, time consuming, and manually done. This is mainly due to the lack of standardized procedures and the absence of specialized instrumentation to automatize the measurements. Thus, the transfer of liquid phase adsorption methods to a wider market of laboratory instrumentation has significant market potential for SMEs and promotes materials discovery in industry. Dynamic (flexible) porous materials such as metal-organic frameworks are already recognized as highly selective adsorbents suitable to revolutionize separation technologies. In order to completely unlock the potential of dynamic porous sorbents, industrial R&D Departments, research institutes, and academic institutions require advanced instrumentation for assessing the liquid phase adsorption capacity of dynamic porous materials. DYNALIP aims to develop a novel advanced on-line liquid phase adsorption technology to perform quantitative and exact liquid phase adsorption measurements. The successful project completion will allow the commercialization of an advanced device for laboratory use to promote the discovery and analysis of novel porous materials for highly selective liquid phase separation applications.