RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Increasing the efficiency of European food supply chain through in-memory supply chain planning' under Horizon 2020.

assistant: **Concept**

RELEX has built an innovative supply chain management solution for the demand forecasting and inventory optimisation of retailers and wholesalers. Unlike traditional supply chain management solutions, RELEX’s is built on a unique columnar in-memory database and uses optimisation algorithms based on the supply chain research of the company founder. As a result, it is less costly, more flexible and much faster than traditional disc-based solutions. RELEX’s main future challenge is to develop the solution’s functionalities and scalability to better serve food retail and wholesale sectors, where the business benefits are the greatest, and develop a marketing and deployment process and organisation to support rapid internationalisation. The project enhances RELEX’s capabilities to address the whole European food supply chain market. When launched, the solution will enable food retailers and wholesalers throughout the EU to decrease spoilage, increase profits and improve customer service. In the EU scope, spoilage reduction would amount to 11–30 million tonnes p.a. This would reduce CO2 emissions by 22–60 million tonnes. The same challenges in food supply chains not limited to the EU, hence the innovation has potential for a global reach.In the feasibility assessment we will 1) prioritize product development requirements for maximum market impact by listing development options and rating them with (prospective) customers, 2) generate a market entry plan based on macro level data on numbers and company sizes of food retailers and wholesalers in EU countries, 3) select the best way for scaling up the processing capacity by evaluating product development needs for using clustered servers or public cloud server capacity and comparing cost structures of these options, and 4) gener
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Terahertz heterodyne receiver components for future European space missions' (TERACOMP).

assistant: **Concept**

Sub-millimetre wave or terahertz heterodyne receivers are key instruments for many space applications. For example, they are required for monitoring of the earth’s atmosphere or detection of molecules that might be tracers of life on other planets or moons. However, key components of these systems are currently supplied from outside Europe and performance as well as mass and power requirements often prohibit the implementation. The TeraComp project aims at developing European industrial level capability to design and manufacture terahertz front-end electronics based on high frequency Schottky diodes, Heterostructure Barrier Varactor (HBV) diodes and mHEMT MMICs for space and other applications. The prototype components will be integrated into a compact 557 GHz heterodyne receiver and evaluated for space instrument applications. The front-end demonstrator consists of a low noise 557 GHz subharmonic Schottky diode mixer, a 275 GHz Heterostructure Barrier Varactor frequency tripler and a 92 GHz mHEMT power amplifiers and a 15 to 92 GHz 6x multiplier as part of the local oscillator chain. This development will significantly contribute to mass and power reduction and it will improve the performance of terahertz heterodyne receivers. In addition, the dependence on critical technologies and capabilities from outside Europe for future space applications will be reduced.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Site-Specific Heteroatoms Doped Graphdiyne as Metal-Free Electrocatalysts for Nitrogen Reduction' (GDYNRR).

assistant: **Innovation**

Eletrocatalytic nitrogen reduction reaction (NRR) has rencetly emerged as a sustainable alternative for ammonia production. However, the metal-based electrocatalysts for NRR suffer from low efficienciess due to the competing hydrogen evolution reaction. Heteroatoms doped carbon based metal-free catalysts feature weak integration with hydrogen, making them potential candidates for NRR. The NRR activity depends closely on the the form of doped atoms. The pyridinic N atoms and BC3 structure are demonstrated as the most active sites for ammonia synthesis. However, for widely researched carbon materials, it is difficult to selectively dope a sufficient amount of site-specific pyridinic N or BC3 atoms. As a lamellar carbon allotrope, graphdiyne (GDY), constituted by sp- and sp2- carbon atoms, is a great breakthrough. The high energy of sp-hybridization of acetylenic linkages enables the arbitrary angle rotation of π/π* perpendicular to the axis, endowing it a possibility to point towards N2. Another important feature of GDY is that it can be synthesized in solution via bottom-up method. A controllable heteroatoms doping method using a monomer design strategy, provides an ideal solution to achieve the site-specific doping. However, the attempt to design site-specific pyridinic N or BC3 atoms doped GDYs for electrocatalytic NRR has never been reported.The objective of this project is to selectively dope the site-specific pyridinic N and BC3 atoms into GDY to achieve the high performance and selectivity towards NRR. The influence of the pyridinic N and BC3 structure on the properties of GDY will be studied. Afterwards, the prepared site-specific heteroatoms doped GDYs will be used as electrocatalysts for NRR. Owing to the exact doping structure, the catalytic mechanisms for NRR
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Expression and function of the endogenous inhibitor of the mitochondrial F1F0-ATPase, IF-1, and its role in shaping the cellular response during ischaemia and cell death' in the context of a Sixth Framework call.

assistant: **Objectives**

ATP fuels all cellular processes and is fundamental for life and well-being. Mitochondria, which play a central role in cell regulation, are the principal source of cellular ATP. It is increasingly clear that defects in mitochondrial function underlie many major diseases (e.g. of the heart and central nervous system).The ATP produced by mitochondria is synthesised by the F1-F0 ATP synthase. The enzyme is a proton motive ATPase, which is driven as an ATP synthase by the proton motive force, expressed primarily as a potential. If the potential collapses, e.g. under pathological conditions such as anoxia, the enzyme reverts from ATP synthesis to ATP hydrolysis, glycolysis becomes the only source of cellular ATP and mitochondria act as ATP consumers.IF-1 is a protein, which inhibits ATPase activity. It binds the F1 sector of the ATPase, limits its hydrolytic activity and so protects the cell from ATP depletion. IF-1 is therefore a key determinant of cell survival during potentially lethal events such as ischemia, a major cause of death in industrialized countries. Furthermore, as the pathway of cell death to apoptosis or to necrotic cell death depends on ATP availability, IF-1 may play an important role in defining the pathway to cell death.Remarkably, despite extensive and detailed knowledge IF-1 at a molecular level little is known about its comparative cell physiology between cell types and between species. The aim of my research training at the Physiology Department of the University College London is to characterize the functional contribution of IF-1 in physiological and pathological conditions.Specifically, we plan- to examine IF-1 expression and localization in different tissues and different species- to use molecular biological techniques to generate recombinant pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Evolution of Dense Star Clusters with Massive Black Holes'.

assistant: **Objectives**

In this proposal we outline our programme for developing a software environment for simulating dense star clusters, the formation and evolution of massive black holes in these systems, and their interactions. We propose to develop a computer code which brings together the attractive aspects of direct N-body integration (realism, minimal simplifying assumptions) and Monte Carlo techniques (speed, ability to handle large number of particles). Our new code will allow us to simulate the evolution of rich clusters containing massive black holes with unprecedented realism. As a particular application we will test the validity of orbit library method for globular clusters domain. In addition, we will extend direct N-body approach of modeling these systems, by using a realistic number of stars. The simulations we plan to carry out will also provide insight on galactic nuclei, in particular the inspiral and the capture of intermediate mass black holes by supermassive black holes at the centers of galaxies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Dissecting and targeting malignant cell-fibroblast crosstalk driving cachexia in pancreatic cancer' (CAFinCAC) targeting Horizon Europe.

assistant: **Abstract**

Cancer-associated “cachexia” is a debilitating condition that causes patients to lose weight and muscle, which limits treatment options and worsens survival. Often patients diagnosed with pancreatic cancer, a lethal and increasingly common malignancy, are affected by cachexia. Little is known about cachexia and no therapies exist. It is thus important to identify causes of cachexia to develop treatments. Pancreatic tumours contain abundant non-cancerous cells, called ""fibroblasts"", that promote cancer progression. My host laboratory found various types of fibroblasts that promote pancreatic cancer in different ways. Moreover, they found that genetic mutations of the cancer cells change the fibroblasts. While lots is known about how fibroblasts promote cancer, we know little about how they affect cachexia. My research objective aims to identify features of pancreatic cancer fibroblasts that promote cachexia to guide the development of therapies. I first aim to determine how genetic mutations that alter the composition of pancreatic cancer fibroblasts affect cachexia (Objective 1). I will then test how pancreatic cancer-associated cachexia is affected when  fibroblast composition is altered using mouse models that were recently engineered by my host laboratory (Objective 2). This work will highlight candidate therapeutic targets of cachexia. Importantly, cachexia also affects patients with other cancers and diseases, and fibroblasts in these conditions share features with pancreatic cancer fibroblasts. Thus, my project could have a broad impact.My research background in pancreatic cancer and the models of the host laboratory will guarantee the successful completion of this project. Working with the host supervisor, a world-leading expert on pancreatic cancer fibroblasts
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'A Reconfigurable robot workCell for fast set-up of automated assembly processes in SMEs' to be submitted under Horizon 2020.

assistant: **Abstract**

ReconCell develops a new type of robot workcell, its required process infrastructures and the economic framework for automated robot assembly, especially designed for the needs of SMEs. SMEs would benefit from robotic automation, but often cannot use it due to set-up & maintenance complexity. This requires expert knowledge and time for configuration and programming, which is too costly for them. Robotic automation is, thus, normally economically infeasible for SMEs, especially for small batch sizes. ReconCell develops an easy to (re-)configure and (re-)program workcell, making robot solutions commercially viable even for small batch sizes (~1000 units) by reducing set-up & maintenance effort substantially.Specifically, the ReconCell System is based on a layered concept where we start together with the customer with business modelling the planned product assembly based on the ReconCell System to assess its economic viability and provide decisive Key Performance Indicators (KPIs). On approval, the next layer of the ReconCell System implements assembly with automated testing in simulation. Here we use reconfigurable hardware elements to design the required workcell layout and assembly processes. After verification, product assembly takes place in the real workcell under machine vision-based monitoring and novel force-based control of execution to assure product quality using the KPIs. We demonstrate the capabilities of the layered ReconCell System on three real use cases provided by the SMEs of our consortium and two more use cases, established through an open call. In addition, the consortium has started to establish a network of potential ReconCell users to disseminate information about ReconCell technologies to all actors in the value chain, and to raise awareness about
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Exploration of Unknown Environments for Digital Twins'.

assistant: **Innovation**

In the 'explorer' project, we will develop methods for automatically capturing and labelling video data in ""open worlds"".  The ultimate goal is the great facilitation of the creation and maintenance of Digital Twins: Digital Twins are virtual 3D copies of complex scenes such as cities, factories, or construction sites.  Not just a 3D reconstruction, they should capture the scene's semantics, i.e.  the identity of each object and the scene's dynamics, i.e.  how objects move.  Because Digital Twins have the potential to be extremely useful for monitoring large complex sites and planning the development of these sites, their forecast market is huge, they remain mostly a concept because of important limitations of the current technology.  Our methods will guide autonomous systems such as robotic platforms and UAVs through complex and unknown environments to capture visual data for creating and maintaining Digital Twins.  This is extremely challenging as these systems will encounter objects without any prior knowledge about them and will have to collect sufficient data about them.  To the best of our knowledge, this active and automatic capture in complex real environments is a new problem.  It is however very important to solve it as this will relax the need for human expertise and time: Currently, capturing such data is done manually only by researchers and requires strong understanding of what the learning algorithms require.  To tackle the complexity of this problem, our approach is inspired by techniques from Artificial Intelligence applied to the exploration of extremely large trees.  This approach will allow us to bring the perception part and the planning part of the problem together under the same optimization framework, to formalize it and solve it efficiently.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Quintuple Helix Approach to Targeted Open Innovation in Energy, Water, Agriculture in the South Mediterranean Neighborhood' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

5TOI_4EWAS project will focus on Targeted Open Innovation in energy, water and agriculture societal challenges through a balanced innovation-friendly ecosystem in the Southern Mediterranean Neighborhood (SMN) based on quintuple helix and NEXUS approach. The project will enhance and support regional smart specialization and development by increasing research capacity, effective mobility of young innovators/researchers and shared knowledge to improve their participation in the EU research area. It will contribute to the establishment of favorable and stable conditions for international cooperation and the set-up of a Common Knowledge and Innovation Space of specialization in the SMN for a real socio-economic impact, based on co-ownership and mutual benefits.Our partnership ensures coherence and complementarity with past and on-going regional EU-MPC cooperation initiatives and existing bilateral S&T Agreements. The project allows easily building of synergies among several ongoing initiatives thanks to the established Think Tanks Network of Science Counselors in the MPC area and the observatory of current initiatives. In this way, the project will seek continuous complementarity and coherence with the activities of the Strategic Forum for International Cooperation to enhance the cooperation and close synergies through the involvement of the widest possible range of stakeholders, from funding agencies, research organizations, industry to civil society. Therefore an enhanced and more reliable definition of the priority setting mechanisms in the region from an innovation point of view is expected. Through these activities and by the definition of a Join Action Plan, the project will effectively use the science diplomacy and facilitates the identification of remaining obstacles
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Roman cement to restore built heritage effectively'.

assistant: **Innovation**

Roman cements - highly hydraulic natural binders - were key materials to decorate facades of buildings in the 19th/early 20th centuries. Unfortunately, they are no longer available on the market. Consequently the fundamental principle of modern conservation - that the historic buildings should be repaired by using materials that are compatible with the original historic substance - cannot be meet when restoring this important built heritage. The objective of the project is to re-establish manufacture and use of Roman cements. This will be achieved by studying historic mortars to establish compatibility criteria, selecting appropriate raw materials, optimising cement stone calcinations conditions in the laboratory and in a commercial kiln, carrying out workshop and conservation trials. Results will be disseminated to material producers and end-users of the technology - restoration workers and authorities.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Greenland’s Melting Firn and Ice Sheet Response' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

TheThe FirnMelt ERC Synergy project focuses on the Greenland Ice Sheet’s reaction to surface melting across its vast firn plateau, currently covering almost 90 % of its surface. Firn is the up to 100 metres thick, porous near-surface layer of compressed snow. Most of Greenland’s firn plateau experienced only occasional melt in the past but ever rising temperatures increase melting and it is uncertain how much of the melt refreezes or runs off. Current state-of-the-art firn models were built on the earlier premise that firn experiences little melt and are fundamentally limited in modelling melting firn. Consequently, we need a paradigm shift to a new generation of models simulating the physics of melting firn. When coupled to ice sheet hydrology and ice dynamics models, these new firn models will enable assessing how a melting firn plateau will impact mass balance, hydrology and dynamics of the ice sheet. The FirnMelt team will tackle this opportunity through (i) large-scale in situ and remote sensing measurements of all types of firn and meltwater discharge, (ii) develop new physical parameterizations of melting firn based on these measurements, (iii) develop a new generation of models able to simulate melting firn and firn meltwater discharge in three dimensions, and (iv) embedding these models into a fully coupled ice-sheet model suite. (v) Eventually, we will calculate how the melting firn plateau will impact the entire ice sheet and its sea level contribution, until the year 2300. To date, no such concerted effort has been undertaken. FirnMelt unites a team of four world-leading PIs whose combined thematic expertise in firn processes, ice-sheet dynamics, remote sensing and numerical modelling makes such an ambitious effort possible. Our research will have profound i