RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Early-life stressors and LifeCycle health', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Early life is an important window of opportunity to improve health across the full lifecycle. European pregnancy and child cohort studies together offer an unique opportunity to identify a wide range of early life stressors linked with individual biological, developmental and health trajectory variations, and to the onset and evolution of non-communicable diseases. LIFECYCLE will establish the EuroCHILD Cohort Network, which brings together existing, successful pregnancy and child cohorts and biobanks, by developing a governance structure taking account of national and European ethical, legal and societal implications, a shared data-management platform and data-harmonization strategies. LIFECYCLE will enrich this EuroCHILD Cohort Network by generating new integrated data on early life stressors related to socio-economic, migration, urban environment and life-style determinants, and will capitalize on these data by performing hypothesis-driven research on early life stressors influencing cardio-metabolic, respiratory and mental health trajectories during the full lifecycle, and the underlying epigenetic mechanisms. LIFECYCLE will translate these results into recommendations for targeted strategies and personalized prediction models to improve health trajectories for current and future Europeans generations by optimizing their earliest phase of life. To strengthen this long-term collaboration, LIFECYCLE will organize yearly international meetings open to pregnancy and child cohort researchers, introduce a Fellowship Training Programme for exchange of junior researchers between European pregnancy or child cohorts, and develop e-learning modules for researchers performing life-course health studies. Ultimately, LIFECYCLE will lead to a unique sustainable EuroCHILD Cohort Ne
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Standardisation of a guideline for the measurement of tars in biomass producer gases (tar measurement standard)' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

Measurement methods and definitions for organic contaminants in biomass gasification based CHP-systems are numerous and non-uniform. So, comparison of data and definition of maximum allowable concentrations for the contaminants is problematic. This is an obstacle for market introduction of CHP systems as the contaminants can cause damage or an unacceptable level of maintenance. Therefore, in a previous EU project, a Guideline for tar measurement (the Guideline") was developed. Although several institutes have now used this Guideline, it does not have the status of an international standard yet. The objective of this project is to remove this obstacle by standardising the Guideline. The result will be a CEN Standard. As acceptance and use by others is considered to be essential, dissemination and internalisation of the Standard forms part of this project."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Branching and fragmentation processes' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

This proposal aims to establish Dr. Piotr Miłoś as an active and independent researcher in the field of stochastic spatial models and more precisely branching and fragmentation processes. He is to master new techniques and skills which will allow him to further develop an independent career. The Fellowship will lead to publications in leading probability journals and long-term collaboration with the probability community in the United Kingdom. This will result in mutual benefits for both the Polish and British scientific societies.Piotr Miłoś will join the Probability Laboratory at Bath, a leading probability group in the United Kingdom. He will primarily work with Dr. Simon Harris solving problems in areas of branching and fragmentation processes. He also hopes to benefit from collaboration with Dr. A. Kyprianou, a leading expert in Levy  and fragmentation processes, and Dr. P. Morters, a leading expert in the field of stochastic models.The rest of this proposal summarises the scientific problems Piotr Miłoś will investigate at Bath. The knowledge and experience acquired will provide him with new opportunities to contribute to the field. This will enable him to continue an active scientific career after the Fellowship is completed.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Using Psychophysical And Neuroimaging Tools To Identify The Mechanism Underlying Perceptual Dominancy In Vision' (2014-2020).

assistant: **Innovation**

Grouping principles are utilized for the construction of visual information into coherent percepts. Several grouping principles are usually present in the same scene and often lead to several possible organizations. However, our conscious percept is usually of one stable organization at a time. Very little is known about the mechanism by which the competition between alternative organizations is resolved. The proposed study is designed to fill this gap, and to reveal the mechanism using behavioral measures (i.e., accuracy and reaction times) as well as neuroimaging tools (i.e., EEG). The specific research objectives are: (1) Identifying the factors that affect the competition and their relations; (2) Evaluating the roles of visual encoding and mental representations in the competition; and (3) Identifying the neural correlates of the competition.Training objectives: (1) Gain knowledge in new research methods (i.e., EEG); (2) Enhance experience in mentoring and supervision to improve transfer of knowledge; (3) Refine skills in funding applications and project management; (4) Extend track record of conference presentations and publications; and (5) Expand involvement in gender issues. During the fellowship I will  acquire new knowledge and skills in neuroscience to complement my expertise in cognitive psychology research. Intensive hands-on training using state-of-the-art equipment and facilities will be provided under the close supervision of world-class expert. Since there is a growing demand in universities in Europe and worldwide for vision researchers showing inter-disciplinary approaches and skills, the fellowship will have a tremendous impact on my career and open more job opportunities for me.The host lab offers a multidisciplinary approach, including computationa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'ADDI-OPTIMISE - Process Efficiency & Quality Assurance in Metal Additive Manufacturing' (ADDI-OPTIMISE) under Horizon 2020.

assistant: **Objectives**

Croom Precision Medical (CPM) is an SME with over 35 years’ experience in partnering with global healthcare and aerospace companies as an outsourced manufacturing service of high precision components and medical devices. The overall goal of this ADDI-OPTIMISE project is to achieve a significant step change in the quality and yield of regulated components produced by metal Additive Manufacturing (AM) and as a result to deliver enhanced cost competitiveness. CPM wants to capitalise on our existing practical know-how to develop new services for application in its own business but also as a service to other European AM businesses. When evaluating the metallic AM process in a regulated medical, aerospace or automotive production settings, there is significant process flow challenges in place which requests high value metallic volatile material enter multiple environments for sieving, cleaning and recycling. This introduces multiple opportunities for hazard and material contamination from foreign particles. The competitive advantage for this project and its innovation will be realised by the ability to translate advanced technology, in-situ process monitoring information, post-processing and validation into superior product performance, reduced process waste and improved lead times against current AM processes. The output of the project will provide a robust platform that will allow us to develop multiple product lines and services to meet the needs of a rapidly developing sector.  We have a vision of accelerating the uptake of additive manufacturing and disruptive technologies from the SME right through to the multinational in a bid to meet market demands in the highly regulated aerospace and medical fields. Additive Manufacturing or 3D printing in metals is disrupting these
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Local Training Network on REgenerative medicine and Stem Cell technology in UtrEcht' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

With an aging population, a growing burden of chronic conditions, and rising healthcare costs in Europe, the need for organs, tissues, and personalized strategies for decision making in therapeutic choices has never been greater. Recent developments herald the promise of regenerative medicine and stem cell (RMSC) technology. However, for RMSC to fully capture its potential, a synergistic and multidisciplinary effort remains necessary to achieve essential scientific breakthroughs.There is thus a high demand for an excellent graduate program that trains a new brand of researcher who will successfully bring RMSC technology from bench to bedside and back. Such a researcher understands the needs and demands that exist in the clinic, the strengths and limitations of RMSC technology and its ethical and regulatory aspects, and has the entrepreneurial spirit to push their discoveries towards new applications. Therefore, the University Medical Centre Utrecht (UMCU) has initiated the RMSC-dedicated doctoral training programme RESCUE. RESCUE features an international, interdisciplinary and inter sectoral approach to train 29 highly skilled Early Stage Researchers (ESRs) to become the future leaders in RMSC research and implementation of RMSC technology. RESCUE brings together 31 principal investigators that are renowned experts in their fields, have ample experience with supervising PhD students and leading successful research groups. RESCUE is tightly connected with multiple international academic and private partner organisations, each providing complementary research or training.  RESCUE enables UMCU to develop best practices in high quality training and research. The long-term ambition of RESCUE is to establish a strong and coherent network that connects highly skilled young re
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Unmasking the molecular mechanisms mediating the antiatherogenic effects of GLP-1RAs' (AtheroGLP1), addressing dissemination and exploitation.

assistant: **Impact**

Cardiovascular diseases (CVD) are highly prevalent in Europe, causing more than 3.9 million deaths yearly. Atherosclerosis, a chronic inflammatory disease of the arterial wall, is the main underlying cause of CVD.  Available strategies to treat and prevent atherosclerosis remain suboptimal, therefore, better understanding of its regulatory mechanisms is required to design new approaches to treat this inflammatory disease. Recent cardiovascular outcome trials demonstrated that GLP-1R agonists (GLP-1RA) reduce the rates of major cardiovascular events. This GLP-1RA effects are hypothesized to reflect modifications on atherosclerosis, through anti-inflammatory actions. However, the mechanisms linking GLP-1R activation to control of atherosclerosis and vascular inflammation, as well as the cells/tissues mediating these effects, are far from understood. The main aim of my proposal is to identify the mechanism by which GLP-1RA regulate atherosclerosis regression, offering a unique and innovative opportunity to study the role of yet unexplored GLP-1R+ cell types (vascular smooth muscle cells, and neurons of the enteric and central nervous system) mediating its effects. The multidisciplinary perspective adopted, combining my background in academic research with preclinical models, the experience in biomedical research of the host supervisor, and the clinic/translational perspective of the partner supervisor, gives this AtheroGLP1 project with the strong potential to identify novel mechanisms that are expected to have immediate translational importance for targeted use of GLP-1RAs in the clinic to treat atherosclerosis and CVD. Importantly, this proposal will allow me to gain transferable competences and get trained in the latest in vivo and molecular techniques to assess vascula
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Expediting Adoption of e-working Collaborative Environments' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

The project will review and analyse the technical, organisational, economic, market, legal and regulatory factors for the adoption of new Collaborative Tools in e-Working environments for e-Business, e-Professionals and e-Government across EU member states in a number of targeted studies. Furthermore, it will produce policy, organisational and technological recommendations, which can be used to overcome the identified obstacles and maximise the benefits of the Working Environments value process. It will also describe current and future technological trends expected to play a key role in this field, and include a reference to the role of Open Source Software (OSS). The project will implement a common virtual space via the Collaborative e-Working Environment (CeW) platform for the collaboration and knowledge sharing of communities involved in the development of technologies and policies for e-Working environments based on the research results of the project.CeW will be an open initiative where companies, organisations and individuals from different Member States can have access to information regarding Collaborative Working environments and contribute irrespective of size or locality. The platform will act as an electronic work environment in which the numerous continuously changing networks of companies that create added value collaborative working environment products and services are supported by extremely high quality e-Collaboration tools and services for effective B2B, B2C, B2A transactions. The demonstrator will serve also as an example of applying the project recommendations and good practices for e-Working environments design and implementation across EU member states.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'New paleoreconstructions from Antarctic ice and marine records' (EPICA-MIS).

assistant: **Concept**

The objective of the Specific Targeted Research Project EPICA-MIS is to produce palaeoreconstructions and integrated climate analysis through marine and ice core studies. It will contribute to the development of novel paleoreconstruction methods by providing unique paleorecords and developing new proxies of critical properties of the climate system. The two Antarctic deep ice cores will be completed and they will for the first time reveal atmospheric records of greenhouse gases like CO2 and methane reaching 800,000 years back in time.Novel multi-parameter and high-resolution records of climate-relevant parameters like ice isotopes, greenhouse gases, dust and soluble impurities will be produced from the new Antarctic ice cores. They will be compared and correlated with palaeoreconstructions from marine, Greenland and other Antarctic re A key task here is to produce common timescales for the records by comparing the individual datings and by investigating novel tephra and paleomagnetic correlation methods. The produced multiproxy reconstructions will provide an outstanding platform for understanding and modelling the past and present climate. Because the reconstructions from both ocean and ice cores will be integrated and will use novel indicators for instance for sea ice, Antarctic insolation, iron or opal isotopes, climatic issues like the carbon cycle, sea surface temperature, and the climatic coupling between the northern and southern hemispheres can be addressed with new perspectives.As strategies for mitigation and adaptation to global change have to be based on predictions on future climate, the EPICA-MIS novel palaeoreconstructions will produce new evidence about climate dynamics and variability necessary to improve and test policy-relevant models. The Research Pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Functional comparative Genomics and loss of function study of Vertebrate Iroquois A Genes' (IRXAVNS), addressing dissemination and exploitation.

assistant: **Impact**

The Iroquois (Irx) genes participate in numerous events during vertebrate neural development, such as antero-posterior and dorso-ventral subdivision of the developing nervous system. However, most of the information about their function and regulation still remains unknown.Mammalian Irx genes are arranged in two clusters, IrxA and IrxB, containing three genes each. To understand the role of Irx during development it is imperative to unravel the regulatory networks in which these clustered genes are immerse d. Dr. Gómez-Skarmeta group (CABD, Seville) has taken advantage of the availability of whole genome sequences for a number of vertebrate model systems to identify putative enhancers within the Irx clusters.By using evolutionary conservation as a guide for important genomic sequences, they have found many conserved non-coding regions located along both Irx clusters (unpublished data). I wish to incorporate to his group and focus in the study of function and regulation of the Iroquois A cluster.The purpose of this project is:- To examine whether the conserved regions harbour specific enhancers in vertebrates (mouse, Xenopus, zebrafish) using genomic comparison and generating transgenic animals with these regions;- To characterize the regulatory and signalling pathways that act on some of these enhancers in different vertebrates by a combination of different biological disciplines and techniques (bioinformatics, animal cap, dominant negative forms);- To explore the defects associated with loss of function of single, or combinations of, Irx genes using morpholinos in Xenopus tropicalis.Additionally, in the next future, we will determine whether these elements and the pathways that activate them can be used to differentiate mouse stem cells towards specific neural fates. T
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Bioinspired Composites Strategies for Saving Energy' (BioCom4SavEn).

assistant: **Innovation**

Saving energy together with energy harvesting is demanded by increasing power consumption. The energy industry requires new materials not only for construction but also in cabling infrastructure. Moreover, the trend of portable and small devices causes a significant challenge in heat dissipation technologies. The need for sustainable technology in thermal insulation and cooling solutions to decrease power consumption requires new innovation. My ambition is to bring novel solutions inspired by nature to the thermal management challenges such as:-constructing light and more efficient thermal insulation; -developing cooling system based on the fibrous membranes to dissipate effectively heat, both leading to lower power consumption; -building mechanically robust and integrated system with conductive or piezoelectric properties, including thermal insulation and cooling system designed together for small devices and smart textiles.The aim of the project is therefore to both comprehensively evaluate natural design strategiesand develop structural equivalents using novel composite manufacturing routes. Key to composite production is electrospinning allowing engineering the novel composites based on the porous membranes that will transform thermal energy management efficiency, allowing to increase the savings in daily life.The novelty of the project is the combined effort of complex composite membranes that have been never performed before. The interdisciplinary team of postdocs and PhD students working in parallel on the divided but interlayered topics, will lead to break-through in engineered multifunctional thermal materials for various geometries from buildings to cables.


**Keywords:** electrospinning, fibers, polymers, thermal insulation, biomimetic, cooling, pores, poros