RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Stagnation proof transparently insulated flat plate solar collector (STATIC-2)' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Objectives and Problems to be Solved:· Development of new concepts for the protection of TIM-collectors in stagnation conditions by taking account of the energy storage capacity of collector. New materials such as Phase Change Materials (PCM) will be looked into (very innovative).· Design of optimised stagnation proof TIM-collectors for working temperatures between 110 to 150 oC so as to give response to the energy market demand for applications at such temperatures (industrial process, LiBr absorption refrigeration machines of double effect...). A cost goal of around 200 EUR/m2 has been fixed for this project (which will be about 50% lower than the commercial evacuated tube collectors).· Consolidation of the use of TIM materials in solar collectors. Research did within this project will increase the experience of using TIM in collectors making easier the introduction of TIM in the active solar energy technology. Description of the working order to achieve the goals of the project, a work plan has been planned based on the combination of four main lines:· Optimisation and design process by means of high level computational tools. Two kind of tools already available and previously used in other projects related to solar energy will be used:. Optimisation and designs codes with little computational effort that allow to find out the most appropriate designs for each situation.2. High level numerical simulation tools for the detailed study of fluid dynamics and heat transfer, by means of a numerical integration of the differential equations governing the physical phenomena.· Accurate measurement of physical and radiative properties of the materials used in the new collectors: PCM, selective surface.... (this data will be used as input data in the numerical tools, making the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The forcing of sea level rise in the Arctic, the North Atlantic and the Mediterranean Sea' (FORSEANAM) targeting Seventh Framework.

assistant: **Abstract**

Understanding the processes that drive sea-level variability is a complex issue, as it involves various local, regional and global features with different time scales, some of them still poorly understood. For this reason, our current capability for producing reliable projections of future sea-level rise is very limited. Advancing the scientific understanding of the key processes that drive sea-level variability is thus required to reduce the uncertainties associated with present projections and allow effective adaptive coastal planning. In this project we attempt to improve our understanding of the sea-level variability observed during the last decades in the North Atlantic and the Mediterranean Sea, identifying and understanding the processes that are crucial to refine sea level projections for the future, all in the geographical framework that is most relevant for the European coasts. The project will make use of in situ data sets, including long tide gauge records and Argo floats, as well as remote sensing data from a variety of satellite sensors including radar altimetry, gravimetry and scatterometry. Ocean models will be used to understand the dynamics of the different processes that drive long-term sea level variability. Focus will be on regional-scale trends, and decadal fluctuations in addition to the underlying long-term trend. In particular, we will study the relationship between the Atlantic and the Arctic oceans, and examine the dynamics of low-frequency basin-scale fluctuations. We will also assess how changes in the Atlantic affect Mediterranean sea level. In particular, we will determine the role of the Strait of Gibraltar in the relationship.  The project will provide an international scientific platform through which the fellow can gain exceptional tra
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Road to Friday of Science and Art'.

assistant: **Objectives**

ReFocuS Art (Road to Friday of Science and Art) project aims to substantially raise public awareness about the importance and positive role of science for and in society by bringing the researchers into the focus of the general public. The 2020 year demonstrated the necessity for the state of the art of science in everyday life and large creativity in the research process to respond to contemporary challenges.Skills, such as creativity, problem-solving and critical thinking will be fundamental for the carriers of today's generations. We argue the same skills are crucial for the researcher career, and instrumental in art as well. Science and art may have different subjects and different audiences but share the investigative spirit, motivation and skills. Both artists and researchers strive to see the world in new ways, and when they succeed in those endeavours, the general public acquires a novel perspective and new knowledge. Both are based on the process which can lead to encouraging to use creativity and critical thinking, and questioning the world around us.This year, by using Science is art as an overall theme, we want to promote the creativity, critical thinking and problem-solving skills of researchers and artists as an imperative for the development of science and society. In this way, we want to inspire and stimulate young people to be innovative and to seek creative solutions to different problems and challenges.The activities will take place in the 14 cities and 46 diverse venues through Serbia, including research institutes, old streets and houses, museums, archaeological sites, fortress, science clubs, shopping malls, city parks and libraries. Some of the activities will be exclusively online, allowing reaching the public outside proposed cities. The diversi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Experimental signatures of quantum electrodynamics in the strong field regime'.

assistant: **Innovation**

Quantum Electrodynamics (QED) is the theory that unifies electromagnetism and quantum mechanics to describe how light and matter interact. Considered as one of the most accurately tested theories, it led Richard Feynman to call it the jewel of physics. Yet, in the strong-field (SF) regime, when the light fields are ultra-intense, this theory is only treated perturbatively and the non-perturbative regime of SF-QED remains a terra incognita as even no theory exists to predict the behaviour of nature. The advent of multi-PW laser infrastructures now makes the SF-QED regime within experimental reach when considering the collision of relativistic electrons with such light pulses focused above 10^22W/cm2. Yet, all planned experiments to probe SF-QED with current technologies only propose to investigate its perturbative regime, expected to be well described by theory.In the EXAFIELD project, I propose a new concept of experiments to exceed the perturbative limit of SF-QED in the lab. This will be achieved by reflecting an ultra-intense laser pulse off a plasma mirror at relativistic speed. The strong Doppler effect occurring upon reflection up-converts the near-infrared laser pulse down to the extreme ultraviolet range which enables both temporal compression to the attosecond timescale and spatial compression down to sub-micron size. This results in a considerable intensity boost at focus of more than three orders of magnitude up to a few-10^25W/cm2.The collision of such a Doppler-boosted beam with ultrashort electron bunches generated from laser-plasma accelerators will allow us to access regimes where the SF-QED can no longer be treated perturbatively, producing very strong signatures in the lab. Characterizing how the observations deviate from the perturbative theory will e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Unlocking the complex genomes of European potatoes for modern breeding' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Potato is one of the three most important food crops in the world. Around 1.3 billion people rely on potato as a staple food every day. But despite this exceptional socio-economic importance, the improvement of potato during the past 150 years has been limited. The main reason for this deficit is the highly heterozygous, autotetraploid genome of potato. This complicates several important aspects of breeding including the fixation of beneficial alleles and the implementation of modern, genomics-assisted breeding techniques.Recently it has been suggested to convert tetraploid potato into a diploid crop, and thereby overcome all the difficulties associated with tetraploid potato breeding. However, the creation of diploid potatoes is hampered by the large number of deleterious recessive mutations that have accumulated in the tetraploid genome and are exposed in the diploid potatoes.In BYTE2BITE we will address the fundamental issues that hold back the success of potato breeding. We will generate the first-of-its-kind, near-to-complete pan-genome of potato and use this resource to develop unprecedented genome-graph tools for efficient genotyping and haplotype-resolved genome analysis. We will then use this new computational toolbox to establish a genomics-assisted pre-breeding programme in which we will generate novel potato cultivars with low mutational load. This new resource will open the doors to efficient breeding unleashing the genetic potential of potato and thereby help to secure the way we feed the world for the decades to come.Specifically, in BYTE2BITE we want to achieve the following goals: 1.A near-to-complete pan-genome describing almost the entire haplotype diversity of potato2.A genome graph tool for cost-efficient genotyping and haplotype-resolved genome ana
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Cirrus microphysical properties and their effect on radiation : survey and integration into climate models using combined satellite observations (CIRAMOSA)' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The radiation effect due to changes of microphysical properties within cirrus clouds can be very important. We will provide a long-term survey of these properties, together with cirrus macrophysical properties, and then establish a compilation of correlations between them and the state of the atmosphere. This information is essential for the understanding of changes in clouds expected by a global climate change. Satellite instruments measuring radiation with a good spectral resolution as well as multi-angular measurements of polarized reflectance used with newly developed retrieval algorithms are now capable to give this information over the whole globe. Extensive care will be taken of the validation of the retrieved cirrus properties by intercomparison with data sets from regional measurement campaigns. Models for climate prediction can profit from the outcome of this proposal by using the most appropriate correlations in their radiation codes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Deciphering Molecular Mechanisms Underlying Outer Membrane Biogenesis of Human Gut Microbiome Species' (Microbi-OM).

assistant: **Concept**

The human gut microbiome profoundly influences health by aiding digestion, defending against pathogens, and producing essential metabolites. While large-scale initiatives have advanced our understanding of microbiome composition and diversity, we still lack fundamental insight into its functional diversity, as many gut species diverge significantly from established model organisms at the genetic and phenotypic levels. This gap limits our ability to design microbiome-targeted therapeutics.Bacteroides, the most abundant genus in the human gut, plays a central role in degrading complex dietary sugars and is thus a prime candidate for therapeutic strategies. A key feature underlying its success in gut colonization and defining characteristic for this phylum is its outer membrane (OM), enriched in surface lipoproteins (twice as many genes compared to E. coli). Lipoproteins come in two flavours: outer membrane proteins (OMPs) and surface-exposed lipoproteins (SELs), which together form a structural scaffold for the OM, and are essential for nutrient acquisition and communication with the host. However, the molecular principles by which Bacteroides traffics and assembles these lipoproteins into a functional OM remain largely unexplored.The Microbi-OM project intends to uncover the mechanisms of OM biogenesis in Bacteroides by dissecting the role of the translocation and assembly module (TAM) complex in lipoprotein surface exposure, (phospho)lipid transport, and coordination with other OM biogenesis pathways. Through high-throughput functional genomics, in situ cross-linking, and proteomics, this project will deliver unprecedented molecular insights into how key gut commensals build and maintain their OM. By expanding the toolkit for studying non-traditional model organisms, Mi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Analyzing metabolism in an unusual nitrogen fixing symbiosis using metatranscriptomics' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

UCYN-A is a globally abundant nitrogen fixing cyanobacterium with a very unusual metabolism and lifestyle. These microorganisms express nitrogenase genes with maximum transcript abundances during the light period (Zehr et al., 2007).Previous results in the group of Jonathan Zehr found that UCYN-A cyanobacteria  are genetically incapable of oxygenic photosynthesis because  the entire PSII apparatus is missing (although the PSI apparatus appears to be intact). Moreover, PSII isn´t the only component that is lacking in this genome: RuBisCo (ribulose-1,5 bisphosphate carboxylase-oxygenase that fixes CO2) and the tricarboxylic acid cycle (TCA) that usually are present in the cyanobacteria, are missing in UCYN-A.The lack of biosynthetic pathways suggested that this organism depend on other organisms, either in close association or in symbiosis, for critical nutrients.Thanks to flow cytometry and the metagenomic studies, this group obtained a complete genome sequence from UCYN-A and observed by quantitative isotopic analysis that UCYN-A has a symbiotic association with a unicellular Prymnesiophyte (Thompson et al., 2012).In this project we will determine whole-genome transcription over natural diel cycle in order to get a better understanding of the interplay of host and cyanobacterium metabolisms, and how it relates to supply of organic matter from the host eukaryote to the cyanobacterium.The transcriptome work will help to determine the global importance of N2 fixation by this cyanobacterial group in order to better constrain the global ocean nitrogen budget.- Thompson, A., R. Foster, A. Krupke, B. Carter, N. Musat, D. Vaulot, M. Kuypers & J.P. Zehr. Science 337:1546 (2012).- Zehr, J., S. Bench, B. Carter, I. Hewson, F. Niazi, T. Shi, H. Tripp & J. Affourtit. Science 322: 11
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'HeartBIT_4.0 - Application of innovative Medical Data Science technologies for heart diseases.'.

assistant: **Innovation**

Support of medical care requires new skills related to effective control of applied medication and methods of treatment, elimination of mutually exclusive medical opinions. There are available technologies to facilitate continuous patient monitoring, including the generation of warning signals, enabling real-time decision support (at the bedside) as well as the ability to dynamically respond to emerging medical conditions and to personalise complex medical care. In the face of progressive digitization, which also involves medicine, acquiring skills, which are based on modern, advanced and state-of – the art computational and analytical techniques, is essential. During the HeartBIT_4.0 project, The Excellence Partners invited to the consortium, will train the staff  from the Department of Heart Diseases of Wroclaw Medical University in the field of Data Science and application of Data Science techniques to medicine. The Department of Heart Diseases has no experience in using modern state-of-the-art methods of analysis and interpretation of large medical data sets. Due to the lack of these skills in the post-industrial era of Big Data and e-society, the Department is forced to accept a secondary role in the contemporary development of biomedical sciences. Establishing the consortium under Horizon 2020 twinning programme and thus formal cooperation with the leading scientific departments from the developed European Union countries that are experts in Biomedical Data Science will significantly increase the scientific potential of the Department. Moreover, the acquisition of the competencies described above will make the Department a valuable partner for future cooperation, research projects at the national and international arena. The acquisition of the above-described comp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Regulation of the Rab GTPases by phosphorylation in Plasmodium falciparum' (MALKINRAB).

assistant: **Innovation**

Plasmodium falciparum, the protozoan parasite responsible for the lethal form of human malaria, causes between 1 and 3 million deaths every year. Within erythrocytes, the malarial parasite is surrounded by a vacuole as a consequence; it is separated from t he extracellular environment by three different membranes. The intracellular survival of the parasite requires a bidirectional vesicular transport system, regulated by Rab GTPases. The aim of this project is to determine whether vesicular transport is regulated in parasites by phosphorylation of Rab GTPases by protein kinases.This application is based in the post-genomic era, where the identification of novel drug targets is facilitated by the availability of parasite genome databases. It is functional genomics and combines genetics with cellular biology and biochemistry. Preliminary experiments have established that P. falciparum Rab11B can be phosphorylated in vitro by the P. falciparum PfPK7. We intend to extend this study to the 10 other parasite Rabs using the 13 protein kinases for which we have active recombinant enzymes.The identification of the regulation network of this bidirectional vesicular transport is essential to understand the development of the parasite. Once we have determined which R abs are substrates for a given kinase we will confirm the interacting complex in vivo by combining Pull-Down experiments and Mass Spectrometry studies. Mass Spectrometry will also be used to identify the phosphorylated residues in each Rab and the site will be altered by mutagenesis.The impact of phosphorylation on Rab-mediated vesicular transport will be assessed by knocking-in mutated P. berghei genes coding for phosphorylation-resistant Rab GTPases. Demonstration that phosphorylation can regulate bidirectional vesic