RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'The European Researchers' Night in Bosnia and Herzegovina 2024-2025'.

assistant: **Innovation**

The European Researchers' Night in Bosnia and Herzegovina 2024-2025 (RiNG-24-25) aim is to bring researchers closer to the general public and to shape a deeper connection between research, creativity and entrepreneurship. RiNG-24-25 will be a flagship science promotion event in BiH with the main focus on increasing awareness of research and innovation potentials in BiH, supporting public recognition of researchers and science-driven entrepreneurs, highlighting research impact on peoples daily life, and encouraging young people to embark on research careers. It will promote the European research and education programmes, inclusion in the European Research Area, and support the BiH path towards the EU.The main objectives are: Enhance researchers public recognition. Increase awareness about research results, especially regarding the daily lives of citizens. Stimulate interest in research careers, in particular amongst young people facing a career choice. Strengthen the connection between research and education by bringing researchers to schools and kindergartens.RiNG-24-25 slogan is Naukatorium: Bridge the Mind, creating a physical and online space for knowledge to connect the minds within the BiH and across the borders.The RiNG is a multidisciplinary STEAM event, aiming to highlight people in Science, Technology, Entrepreneurship, Arts and Makers in BiH and the Western Balkan region. 3 organizations will join forces to bring the science festival to 3 main locations in Sarajevo, Banja Luka and Mostar, and involve another 8 cities in the satellite events.RiNG is aiming to reach over 1 million people during the awareness raising campaign and involve at least 25.000 direct participants in the organized events each year.


**Keywords:** European researchers' night, science com
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The Art of the Impossible: A Philosophical Study of Theatrical Magic' under Horizon 2020.

assistant: **Concept**

PhiloMagic is an interdisciplinary project in philosophical aesthetics in the analytic tradition. It focuses primarily on the art of theatrical magic (think David Copperfield, not Harry Potter), which the American Society for Aesthetics recognizes as a “neglected art.” PhiloMagic builds on my prize-winning essay, “The Experience of Magic,” which is the first systematic philosophical treatment of theatrical magic in the analytic—or, to my knowledge, any—tradition. For my fellowship, I propose a 24-month stay at the Centre for Philosophical Psychology at the University of Antwerp under the supervision of Professor Bence Nanay. While in Antwerp, my main objectives are to complete a book manuscript (entitled *The Art of the Impossible*), write and submit for publication three accompanying scholarly articles, and organize a series of four study groups (each culminating in a public lecture) as well as an international workshop in the philosophy and psychology of magic.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Interference of anthracyclines with cardiac energy signalling: implications for drugs, cardiotoxicity and oncogenic growth' under Sixth Framework.

assistant: **Concept**

Anthracyclines belong to the most efficient drugs of cancer chemotherapy. However, their use is limited by severe cardiotoxicity, whose molecular triggers are not fully understood. Our aim is to analyse novel aspects of cardiac response to anthracyclines, namely signalling pathways regulating cardiac energetics. The ability to respond to altered energy supply or demand is particularly important for heart to maintain its contractile performance. Our approach will integrate a non-biased global analysis of antracycline-induced changes in gene expression and proteome/phospho-proteome with a targeted analysis of the signaling pathway of AMP-activated protein kinase (AMPK).AMPK is a key sensor and regulator of cellular energy state and the drug reduces basic AMPK phosphorylation as we showed recently. The multidisciplinary approach combining biophysical, biochemical, molecular and physiological state-of-the-art techniques will (i) apply different model systems as recombinant protein, cultured cardiomyocytes, isolated perfused rat heart, and cancer cells for comparison, (ii) explore regulatory cross-talk between the AMPK cascade and other signalling pathways or key regulators of cardiac energy metabolism (e.g. creatine kinase), (iii) screen a library of cardioprotective compounds.In scientific terms, we will identify anthracycline-induced changes in the cardiac energetic network and other signalling pathways susceptible to mediate drug cardiotoxic, and possibly anticancer effects. This can provide potent means to modulate drugs toxic and therapeutic activity. In terms of training, fellows goal is to acquire expertise in different cardiac models and in integrative approach (from molecular to physiological) to cardiac bioenergetics and non-scientific skills in a leading medicall
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Self-Organising Capacity of Stem Cells during Implantation and Early Post-implantation Development: Implications for Human Development' (EPIROSE) targeting Horizon 2020.

assistant: **Abstract**

Embryonic development progresses through successive cell fate decisions and intricate three-dimensional morphogenetic transformations. Implantation is the defining event in mammalian pregnancy during which a fundamental morphogenetic transformation is initiated: the body axes are established and the embryonic germ layers created. Despite its importance, a comprehensive understanding of the molecular mechanisms, transcriptional pathways, cellular interactions, as well as the spatio-temporal development of the embryo at implantation stages is at present lacking, due to the embryo’s inaccessibility. To overcome these limitations, we generated a culture system that allows the development of mouse implanting embryos outside of the mother. This system provides the opportunity to address how architectural features and signaling events integrate to induce the emergence of the body plan. Combining this new technology with the analysis of genetically engineered mouse embryos, the aim of this research proposal is to fill the knowledge gap between pre and post-implantation development. Single cell sequencing, two-photon microscopy, high-content forward genetic screening, and modeling will be merged with a functional assessment of embryo development in vivo to reveal the determinants of implantation and early post-implantation development. This global understanding will be employed to explore the extent to which stem cells can recapitulate embryonic development, with tremendous potential for regenerative medicine. Knowledge of the cellular and molecular mechanisms that intertwine lineage specification, developmental potential, and tissue morphogenesis will offer novel insight on the pathological causes of embryo lethality and congenital disorders. The proposed studies will shed ligh
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Green Reaction Control System (RCS)' under Horizon 2020.

assistant: **Concept**

The space industry, and specifically the satellite industry, has experienced a significant growth in the last 10 years. The satellite industry has more than doubled its revenues from $122 billion in 2007 to $261 billion in 2016. It is forecasted an increase even greater for the coming years due to the development of the smallsat business (satellites with weight<500 kg). Latest estimations predict 6.200 smallsats in orbit in the period 2017-2026. For orbital manoeuvring and attitude control, artificial satellites use Reaction Control Systems (RCSs) made up of small rocket engines (thrusters), propellant tanks, valves, etc. Normally RCSs use Hydrazine and Dinitrogen Tetroxide (NTO) as propellants. These are traditional proven rocketry propellants that are now under scrutiny as the space industry significantly grows. These propellants are hazardous for the human health and the environment. NTO is very toxic and corrosive, and hydrazine is toxic, carcinogenic and a mutagen. Besides, this toxicity makes them very expensive to transport and handle. Furthermore, they increase the satellite mass and volume significantly regarding other Eco propellants raising launch costs (average 720 k€). Therefore, there is an urgent need in the market backed up by governments and the EU to replace these propellants by green and safe ones. ECO-Thrust is a clean and safe plug & play RCS for satellites that consume hydrogen peroxide (H2O2) green propellant. H2O2 can be used as monopropellant or as oxidizer with green fuel (like Ethanol or bio Diesel) in bipropellant thrusters. H2O2 is not new for the rocketry industry having being used since 1930. However it has been commonly replaced by toxic propellants since the current catalyst systems for H2O2 entail technical issues and short service live
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Human Genetics of Tuberculosis' in the context of a Seventh Framework call.

assistant: **Objectives**

Tuberculosis (TB) is not only an infectious disease, as only a small fraction of individuals infected with Mycobacterium tuberculosis (Mtb) develop disease. Over the last century, evidence has accumulated indicating that TB is also a genetic disease. However, the molecular basis of predisposition to TB remains elusive, and efforts to understand the pathogenesis of TB are of prime importance if we are to combat this major killer of mankind. The PI proposes an integrated and innovative research program aiming to identify the genetic variants controlling the critical steps of the process from exposure to Mtb to development of TB. In addition to investigating the two key clinical phenotypes - the development of disseminated TB in children and of pulmonary TB in adults - this program proposes to undertake the first comprehensive genetic dissection of resistance to Mtb infection. Making use of the latest conceptual and technical breakthroughs in human genetics, the strategy will combine Mendelian and complex genetics approaches, including genome-wide (GW) investigations (GW linkage and association studies, whole-exome sequencing). The strengths of this innovative, ground-breaking project lie in its bold hypothesis, the high quality of our clinical samples, and the extensive experience of our laboratory in human genetics of mycobacterial infections in terms of genetic epidemiology, molecular genetics, and immunology. The identification of the main variants controlling TB development will have major implications for TB control, both in the definition of new prevention strategies (design of vaccine research and clinical trials) and in the development of new treatments (aiming to restore deficient immune responses). These findings will also shift paradigms in both human genetics
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Seabed Imprint of Dense Shelf Water Cascading' under Horizon 2020.

assistant: **Concept**

Dense shelf water cascading (DSWC) is an atmosphere-driven seasonal phenomenon that occurs in marine regions off Europe and elsewhere. DSWC starts when surface waters over the continental shelf become denser than surrounding waters and sink, generating a near-bottom turbulent flow that moves downslope along the seabed. This process contributes to the deep ocean ventilation and in the global thermohaline circulation (and hence global climate), and involves the massive transfer of energy and matter from shallow to deep waters. While frequently cited as a possible control of the seafloor morphology, there is a lack of studies isolating the DSWC geomorphic effects from other processes known to shape continental margins.This project aims to study the seafloor imprint of DSWC using high-resolution field data and interdisciplinary concepts. The primary focus will be on multibeam bathymetry data sets from 6 areas affected by DSWC. 8 leading research institutions committed to provide the data required. The main expected results are: 1) a better understanding of the physical processes involved in the propagation of DSWC flows, 2) a quantification of their capacity to erode and deposit sediment, and 3) a characterization of the sensitivity of DSWC formation and distribution to climate change in Polar Regions. The host institution expertise on the links between ice sheet dynamics, climate change and marine geological records will be crucial for the training of the applicant and for the success of the project. The planned secondment will add a numerical modelling component so that an in-depth knowledge of the physical processes involved in the propagation of DSWC is achieved. This pioneering work will extend European leadership in the study of DSWC, address EU challenges in the Hori
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'European Research Infrastructure on Highly Pathogenic Agents 2' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

ERINHA2 aims to complete the work carried out during the first preparatory phase (PP1) - ERINHA - in order to reach the financial, administrative and technical maturity necessary to complete the establishment of the Research Infrastructre and ensure that the operation phase can begin in 2018. ERINHA2 will therefore finalise the decision to use the status of an association and prepare the necessary legal document to register the RI depending on the country voted on to host the Central Coordinating Unit. ERINHA2 will prepare all procedures and protocols (human resources, IPR, ethics) needed to effectively operate the RI. The financial and business plans prepared in ERINHA (PP1) will updated and presented to national and international stakeholders to obtain their agreement to fund the infrastructure. An overarching group of activities - WP5, Stakeholders and commitment - will aim to accompany all partner countries in their efforts to obtain agreements and funding. This WP5 will ensure all relevant stakeholders and potential users are informed of the progress, services and benefits of ERINHA. The utlimate outcome of ERINHA2 will be the signtature of the ERINHA statutes among the founding countries to officially establish the RI and enter into the construction phase.


**Keywords:** maturity, financial commitment, agreement, research agenda, legal framework, operational procedure, funding, advocacy, potential user base
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Future INternEt Smart Utility ServiCEs' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Change is the name of the game in energy! The shift to sustainability is visible everywhere. It is now a European priority to combine solutions which utilise energy generation from renewable energy sources and optimize energy usage efficiency into a Smart Energy System based on the introduction of Future Internet technologies.  At the same time, business innovation needs to be encouraged to ensure that job creating SME's can thrive in the new energy eco-system. FINESCE will organize and run user trials in 7 European countries, building on investments of billions of Euro, addressing efficient energy usage in residential and industrial buildings, developing a new prosumer energy marketplace, building a cross-border private virtual power plant, and using electric vehicles as an element of demand response systems, enabling energy providers to move from reactive to pro-active energy network management by providing them with Future Internet ICT, enabling them to better balance volatile solar and wind energy generation with demand for energy.  The FINESCE trials will prove the practical applicability of Future Internet technologies and the FI-WARE Generic Enablers to the challenges of the energy sector. FINESCE will develop an active community of innovative SME's, preparing them for the exploitation of the emerging business opportunities in energy, creating jobs, social impact and economic growth. FINESCE builds on and extends the results of the FI-PPP FINSENY project to realise sustainable real time smart energy services.The consortium includes globally leading energy and ICT operators, manufacturers and service providers and outstanding research organisations and SME's, from 15 countries, contributing directly to tightly focused trials and business innovation. It has the sca
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Next Generation IoT as part of Next Generation Internet' (IoT-NGIN).

assistant: **Concept**

Internet of Things (IoT) is one of the next big concepts to support societal changes and economic growth, being one of the fastest growing ICT segments. A specific challenge is to leverage existing technology strengths to develop solutions that sustain the European industry and values.To address this, IoT-NGIN introduces novel research and innovation concepts, to establish itself as the “IoT Engine” that will fuel the Next Generation of IoT as a part of the European Next Generation Internet. First, IoT-NGIN uncovers a patterns based meta-architecture that encompasses evolving, legacy, and future IoT architectures. Second, it optimizes IoT/M2M and 5G/MCM communications, including using secure-by-design micro-services to extend the edge cloud paradigm. Thirdly, it enables user and self-aware, autonomous IoT systems through privacy-preserving federated ML and ambient intelligence, with AR support for humans. Finally, IoT-NGIN researches towards distributed IoT cybersecurity and privacy, for example, using Self-Sovereign Identities and interconnected DLTs to implement Meta-Level Digital Twins.  IoT-NGIN will be validated via more than 30 types of heterogeneous IoT devices, ranging from tiny resource constrained IoT sensors to intelligent, autonomous buses, drones and robots, deployed in one of the most prestigious IoT/5G lab (OneLab) and five Living Labs: the “Twin Cities” Living Lab in Helsinki/Tallinn, a fully customizable Smart Agri Living Lab in Greece, the BOSCH and the ABB employee-friendly Industry 4.0 facilities in Barcelona and Helsinki, and a hybrid field-lab facility focused on Smart Energy, interconnecting Terni City and EDD Eurolab in Aachen. Beyond partners exploitation plans, to maximize impact and sustainability, IoT-NGIN will push all results via alliances,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'ICT services for Life Improvement For the Elderly' (ICT4Life) targeting Horizon 2020.

assistant: **Abstract**

There are many efforts at European level to improve our ability to monitor health and to prevent, detect, treat and manage disease so that active and healthy ageing can be promoted. In this project, breakthrough research and radical innovation on new services for integrated care is achieved by means of an efficient and cost-effective service-oriented ICT-based collaborative platform which exploits latest advances in sensorization, processing, communications and personalized HMI. ICT4Life will develop a modular Health Service Platform that will allow the provision, easily and in an adaptive way, of 6 ICT4Life Cluster Services for integrated care according to different end-user needs. Addressing the priorities of the European Innovation Partnership on Active and Healthy Ageing, a multidisciplinary approach which integrates expertise and knowledge of medical doctors, nurses, social workers, psychologists, physiotherapists, social scientists, patients as well as programmers and interaction designers is proposed. It relies, from a general perspective, on: New training models for the care workforce; advanced multisensory-based analytics and integration with biomedical devices to have patient activity and health status information; Feedback-based decision-making engine to integrate patient and care provider data; Improve natural interaction mechanisms with patients with interfaces through television with Android TV possibilities, smartphones and desktop applications; Knowledge creation about co-morbidities.Focusing on real medical problems, people with Dementia, Alzheimer or Parkinson disease, constitute the main group of users ICT4Life will focus the analysis on. ICT4Life validation will be done in real use case scenarios in 3 European countries of all this pathologies in ord