RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Plasmons and Mechanical Motions at the Nano-Scale Investigated with Frequency-Domain Experiments and Simulations'.

assistant: **Innovation**

Plasmons are oscillations of charge carriers in metallic nanoparticles that confine light in the nanometer length-scale. Translationally symmetric arrays of metallic nanoparticles, termed Plasmonic Super-Crystals (PSCs), can become an integral part of augmented light-harvesting technologies, like plasmonic solar cells and photocatalysts. A current limitation is that plasmons are fragile, short-living excitations, which are highly sensitive to the exact arrangement of matter at the nanoscale. The structural stability of PSCs is prone to multifarious nanomechanical motions such as nanoparticle-vibrations, colloidal phonons, and surface waves on the substrate. With this project, I aim to elucidate the role of nanomechanical motions on the plasmonic properties of PSCs. To achieve this goal I will employ White Light Absorption (WLA) to study plasmonic resonances and Brillouin Light Scattering (BLS) to study mechanical resonances. Plasmonically-enhanced BLS and spectroscopic investigation of plasmons in vibrationally-excited PSCs, will be used to reveal cross-talking between the two subsystems. A momentum-resolved view of vibrational waves will be acquired with angle-resolved BLS. The experimental results will be interpreted based on frequency-domain, finite-element simulations of plasmomechanical coupling phenomena. With this approach, I intend to adopt the concept of microscopic couplings from condensed-matter Physics, to a metamaterial and determine the fundamental excitations and interactions of these artificial structures. Understanding the interplay between plasmonic and structural degrees of freedom in PSCs is expected to pave the way for their use in plasmomechanical devices.


**Keywords:** Phononic crystals, Brillouin light scattering, colloids, colloidal crystals,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Histone modifications and DNA methylation mapping on the entire Human Chromosome 21' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

As the sequencing of the human genome nears completion, the challenge that faces the scientific community is to decipher the underlying meaning behind these precisely ordered nucleotides. To exploit the vast amount of information now available from the hum an genome sequencing effort, new strategies focused on understanding gene regulation are being developed. One excellent model for these studies is the Human Chromosome 21 (HC21). This chromosome is the smallest auto-some and for this reason, and its clinical relevance in Trisomy 21, is probably the most well-studied chromosome. HC21 has been at the forefront of genomics research in the development of genetic and physical maps, sequencing, gene identification and characterization, and gene expression. In the nucleus of all eukaryotic cells, DNA is highly folded, constrained and compacted by histone proteins in a polymer called chromatin, itself rearranged in the final compacted chromosome. This structure is dynamic and participates in many different fundament al processes of the cell. In recent years it has become clear that chromatin function is extensively modulated by epigenetic modifications, which proceed primarily in the amino-terminal tails of histones and in methylation events of DNA sequence. In our p roject we aim to identify Histones and DNA modifications associated with HC21 transcriptional activity, in a large-scale fashion, using the new exciting ChIP-on-chip approach. This technology has begun to provide insights into the genome-wide study of cell s transcriptional programs, by combining the technique of chromatin immunoprecipitation (ChIP) with hybridization to DNA micro-arrays (chip). In this way, we will establish a precise correlation between epigenetic features and gene expression on the whole h uma
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Toward an understanding of the brain interstitial system and the extracellular proteome in health and autism spectrum disorders' (SecretAutism), addressing dissemination and exploitation.

assistant: **Impact**

Since the ancient Egyptians, the fluid in the brain has been considered a product of spirits, a pathological signature or inert liquid. Even at the turn of the 19th century, when the cerebrospinal fluid (CSF) was first described as a physiological substance, the CSF and the interstitial fluid (ISF), the fluid surrounding all the cells of the brain, were considered solely as a cushion. Only more recently studies have begun to show that the compositions of these fluids can have a marked impact on brain development and animal behaviour. A number of studies have employed omics to demonstrate that the ISF and the CSF are rich in secreted proteins, RNAs and metabolites. However, it is still unclear how these factors influence the development and the function of the brain. Here, we will take a systematic approach to advance our knowledge about the role of extracellular proteins in the brain in health and disease.  Using knowhow in studying the causes of autism spectrum disorders (ASDs) my lab will study the effects of changes in the composition of the extracellular space of the brain at unprecedented resolution and scale. Specifically, we aim to 1) functionally identify proteins of the extracellular space that modulate neural development; 2) study proteins that are packaged into extracellular vesicles and whose mutations are considered high ASD-risk factors; 3) analyse -in vivo- the function of HNRNP U, an RNA-binding protein, which we identified in brain extracellular vesicles and whose mutations are tightly linked to neurodevelopmental disorders.  This endeavour will represent an important step toward a better understanding of the role of extracellular factors in brain development and function. My work will highlight an entire class of protein encoding genes that crucially c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Conjugated polymers with interchain aromaticity'.

assistant: **Objectives**

INTERCHAIN aims to develop and investigate a ground-breaking new molecular design concept for conjugated polymers. The concept is expected to enable the occurrence of stacked-ring aromaticity between polymer chains, drastically advancing our fundamental understanding of stacked-ring aromaticity and introducing a route to exploit this effect for the development of conjugated polymers with excellent charge transport properties.For conjugated polymers with excellent charge transport properties, strong intermolecular interactions are needed, which is difficult to achieve without compromising processability. However, as an emerging class of organic molecules, conjugated macrocycles provide an exciting playing field for the discovery of effects and properties that cannot usually be achieved. In contrast to other molecules, conjugated macrocycles can sustain global aromatic or antiaromatic ring currents, offering exciting prospects to enhance the properties of conjugated materials by enabling exceptionally strong intermolecular interactions. If the macrocycles used are antiaromatic, the interactions between two macrocycles can even result in stacked-ring aromaticity. Integrated into the backbone of conjugated polymers, such macrocycles may enable interchain stacked-ring aromaticity and interchain π‐electron delocalisation, in addition to intrachain π‐electron delocalisation. However, the inherent instability of the required antiaromatic molecules poses a tremendous challenge for the investigation of stacked-ring aromaticity and prevents the development of polymers that exploit this effect.INTERCHAIN proposes a ground-breaking new molecular design concept that overcomes this challenge by eliminating the need for antiaromatic molecules to achieve stacked-ring aromaticity. The pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Modelling Reliability under Variability' in the context of a Seventh Framework call.

assistant: **Objectives**

While feature sizes are continuously scaled towards atomic dimensions, industry is increasingly confronted with unexpected physical artefacts to be considered at each new technology node. Among these, process variation and parameter degradation lead to reliability concerns impacting integrated circuit design at all abstraction levels. As variation and degradation may become a limiting factor for future scaled technologies, there has been a tremendous research effort in understanding these artefacts. Versatile tools, allowing consideration of these artefacts and their combined impact during the design of ICs are still in their infancy. Rather than developing yet another design support methodology, we aim to combine and refine existing reliability and variability prediction methodologies at the abstraction layers with highest industrial importance: Register transfer (RT) level - usual design entry, gate level – where most design for reliability (DfR) techniques are applied, and transistor level - where final sign-off is made.MoRV will cover the strong relationship between variability and ageing, which are usually treated separately, fostering the idea of treating ageing as a form of time-dependent variability. Combined models from transistor, over gate, to RT level will be characterized directly from silicon measurement and all models will be able to interpret the same characterization data base from the silicon measurement.The results will be introduced into a reference design flow combined with a multi-level multi-physics engine. Final goal of MoRV is to enable automated synthesis from specification to circuit. Each model layer will offer reliability and variation prediction for typical and worst case scenarios in order to assess the effectiveness of available design te
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Cerebellar Distributed Plasticity Towards Active Sensing and Motor Control' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The ability to perceive and understand the state of the surrounding environment and the own state is critical for next generation robotic systems. To that aim, the human brain is still far beyond current artificial systems performance due to its capability of processing huge amounts of heterogeneous sensorial data. Interestingly, the cerebellum has been shown to play a crucial role in the generation of dexterous movements as evidenced from cerebellar ataxic patients. Behavioural studies suggest that the cerebellum actively improves sensorial discrimination and proprioception thanks to the prediction of the sensorial consequences of actions. In the last decade, several forms of long-term synaptic plasticity have been observed within the cerebellum, suggesting that distributed plasticity could support the predictive action. However the way in which those mechanisms cooperate in order to improve the function of the whole cerebellar network is not completely understood. In this project, the candidate will develop a novel theory of sensorial information representation and processing based on the cerebellar architecture. The proposed model will make use of long-term synaptic plasticity mechanisms distributed along connections existing in the cerebellar input layer (granular layer) to iteratively create sparse representations of the information, allowing fast and effective learning in successive layers. The predictions extracted from this model will be useful to design new experimental protocols to unveil the cerebellar role in acting and sensing.By providing multiple relevant contributions across the spectrum of the H2020 objectives in terms of its potential to advance robotic manufacturing, brain processing understanding, and novel computing paradigms, this project will enab
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Specific cytotoxic agents to treat prostate disorders in elderly males: targeted gene therapy as an alternative to conventional treatments' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

We aim to develop safer targeted gene therapy as an alternative treatment for prostate disease in the aging male population of Europe, by producing a suite of recombinant viral vectors. These should be brought into clinical trial, in the time scale of the 5th Framework, by collaboration between clinicians and scientists with experience in agrological cancer. Targeting of vectors will be achieved using promoter sequences from prostate-specific genes, and attachment to tumour cells by either antibody reedited adoption or altered capsid/envelopeproteins. Vector specificity will be verified in experimental systems, ranging forming vitro cultures of prostate carcinorna cells, tissue reconstructions, organ culture and engrafts to Phase trials. Special emphasis will be placed on safety aspects: effective targeting vectors will obviate the need for high level inoculations of recombinant virus, and in vivo immune responses will be monitored.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The foreign soldier’s transnational experience in the Nazi military (sphere) – A biographical study of conscripts and volunteers from BeNeLux and their military and individual experience in WWII' to be submitted under Horizon Europe.

assistant: **Abstract**

Over two million foreigners served in the ranks of the Wehrmacht and Waffen-SS. They came from different occupied territories and war zones, or even from uninvolved and neutral countries. These men had a significant impact on the war itself and how it was experienced and conducted. How these men from more than 40 countries experienced the war in German uniform as transnational soldiers remains a black box. TransWarSoldierWWII will trace the experiences of these soldiers by focusing on those who originated from the Benelux to determine the framework of the European war experience from a new angle. This research will deepen understandings of individual biographies of foreign soldiers in WWII from a transnational perspective. This new angle will open up the academic and public discussion on the involvement of non-German soldiers and their entanglement in the war and aims at a profound and critical analysis beyond nation-state narratives. I will be hosted at the Netherlands Institute for War, Holocaust and Genocide Studies (NIOD) in Amsterdam, where Professor Ismee Tames will supervise and mentor me. The research is premised on Responsible Research and Innovation. It will result in a symposium on transnational war experiences, two scientific articles in peer-reviewed journals and dissemination activities in public lectures and a podcast. The project's overall aim is to strengthen my research capacity and skills to assist in securing a leading research position that will enable me to contribute my knowledge and make a crucial impact on this field in military and social history.


**Keywords:** Second Word War; Soldier; Belgium; Netherlands; Luxembourg
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'MEETmeTONIGHT' (MEET).

assistant: **Concept**

MEETmeTONIGHT (MEET) – “Face to face with the research” is the proposal for the European Researchers’ Night in 2020, happening in the major Italian cities of Milan, Naples, Caserta and Padua, complemented by Brescia, Castellanza, Cremona, Edolo, Lecco, Lodi, Mantova, Monza, Sondrio (Lombardy region), Avellino, Portici, Procida (Campania region), Cassino, Frosinone, Gaeta, Ventotene (Lazio region) and Asiago (Veneto region). The goal is to realize a special occasion of meeting and interaction between the public at large and the world of research, where researchers – at the forefront of all the proposed activities – can show themselves and what they do, in a simple, spontaneous, informal and entertaining way, actively involving the public. People, by doing, find themselves learning, getting amused, and becoming aware of how much research is for everyone and all around us. All MEET activities aim at promoting research and its outcomes, researchers and their profession, with a special attention to the youngest generations on one side, and to the recognition of the role of Europe on the other. With one common macro-theme, detailed in five thematic areas and five slogans, MEET proposes interactive stands, hands-on experiments and live demos that reconstruct the research environment; conferences, video projections, interactive games; guided visits to scientific museums; meeting occasions with researchers; European Corners; live broadcast moments. A special attention is given to schools’ pupils, for which a number of dedicated activities are foreseen, at the goal of encouraging them to consider research career as a concrete option for their life, and to sustainability, one of the most important topics to be considered to achieve a better future.


**Keywords:** Responsible Rese
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'From the East End of London to the Favelas of Rio de Janiero: The relevance and transferability of the social legacy programmes of the London 2012 Olympic and Paralympic Games' (LONRIO) under Seventh Framework.

assistant: **Objectives**

The use of sporting and other mega-events to bring about transformation of socially deprived areas of major cities is becoming an increasingly important part  of the raison d'être for hosting such events, especially given the immense costs involved and the current economic climate. The tax-paying public are increasingly having to be persuaded of the benefits, beyond the event itself, to spend the nations resources in this way. London 2012 sold its bid partly on the basis of the potential regenerate one of the most deprived areas of East London made up of the London Boroughs of Newham, Tower Hamlets, Hackney, Waltham Forest & Greenwich, collectively known as the five host Olympic Boroughs. This work proposes to evaluate some of the social legacy programmes of the London 2012 Olympic and Paralympic Games within the 5 London host Boroughs and to assess their transferability to the Rio 2016 Olympic and Paralympic Games with particular reference to the city's favelas. In order to do this it will be necessary to: 1) evaluate the findings of similar programmes at previous Olympic and Paralympic Games; 2) to compare key statistical and other indicators before and after the Games including crime and employment rates, sports participation and perceptions of disability; 3) to compare official government and organising committee findings regarding these programmes with the actual lived experiences of the residents within the 5 host Boroughs; 4) to compare the issues faced by the residents of the 5 host Boroughs before and after the London 2012 Games with those in the favelas of Rio to assess the relevance & transferability of the legacy programmes under evaluation. This research will afford a greater understanding of the impact of local conditions upon the success or otherwise of s