RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'A combined developmental cell biology and tissue engineering approach to repair the articular surface of synovial joints' to be submitted under Horizon 2020.

assistant: **Abstract**

Repair of articular cartilage defects remains a significant clinical challenge due to gaps in our knowledge of articular cartilage development and maintenance in adulthood. This creates a lack of consensus on the ideal cell source for cell-based repair strategies and suitable methods of delivery. The overall goal of ReSurface is to develop a cell therapy platform for articular cartilage defect repair. This will be achieved by unravelling the molecular mechanisms controlling articular cartilage cell development and maintenance, generation of a panel of molecular parameters defining populations of cells that are safe and suitable for articular cartilage repair, and development of a minimally invasive method to deliver cells to the defect site. This project is highly multidisciplinary and intersectoral combining fundamental developmental and molecular cell biology with advanced engineering techniques and including significant industry and clinical collaboration throughout. This fellowship will have an outgoing phase at Dr April Craft’s Lab at Boston Children’s Hospital (BCH), affiliated with Harvard Medical School (HMS) and the Harvard Stem Cell Institute (HSCI), and a return phase to Prof Garry Duffy’s Lab at the National University of Ireland, Galway (NUIG) which is part of the Science Foundation Ireland funded Centre for Research in Medical Devices (CÚRAM). Clinical collaborators will include BCH, Brigham and Women’s Hospital, Boston, University College Hospital Galway (UCHG) and the Regenerative Medicine Institute (REMEDI) at NUIG while industry collaborators include Boston Scientific Limited (BSL). Having recently completed my PhD in biomaterials development, this project will diversify my professional competencies through advanced training with intersectoral and inte
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Physical bottom Up Multiscale Modelling for Automotive PEMFC Innovative performance and Durability optimization' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Proton Exchange Membrane Fuel Cells (PEMFCs) are complex nonlinear systems. In order to improve their durability, efficiency and to decrease the cost, time of development, design of new diagnostic tools is crucial.Powerful mathematical models of the dynamic behaviour of PEMFCs are necessary for the design and improvement of diagnostic tools. The project PUMA MIND will enhance the understanding of interaction, competitions and synergies among the mechanisms at multiple scales and lead to the development of robust dynamic macroscopic models for control-command purposes with predictive capabilities.The novel mathematical models developed by PUMA MIND will be tested by an experimental work, in order to ensure the applicability on commercial attainable components and catalysts. The most suitable catalysts for the MEA manufacturing technology will be used for these experiments. The implementation of the developed models on the mentioned above catalysts might allow a significant impact, and might also contribute to the most promising solutions based on current EU industrial available components. Operation conditions and control strategies to enhance the durability of automotive PEMFC will be derived on the basis of the multiscale modeling approach proposed by PUMA MIND.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Secure Enclaves for REactive Cloud Applications' (SERECA) targeting Horizon 2020.

assistant: **Abstract**

Cloud security is of immediate concern to organisations that must comply with strict confidentiality and integrity policies. More broadly, security has emerged as a commercial imperative for cloud computing across a wide range of markets. The lack of adequate security guarantees is becoming the primary barrier to the broad adoption of cloudcomputing.The Secure Enclaves for REactive Cloud Applications (SERECA) project aims to remove technical impediments to secure cloud computing, and thereby encourage greater uptake of cost-effective and innovative cloud solutions in Europe. It proposes to develop secure enclaves, a new technique that exploits secure commodity CPU hardware for cloud deployments, empowering applications to ensure their own security without relying on public cloud operators. Secure enclaves additionally support regulatory-compliant data localisation by allowing applications to securely span multiple cloud data centres.Although secure enclaves are a general mechanism, SERECA focuses on a particularly important and rapidly growing class of applications: reactive applications for the Internet of Things (IoT), Cyber-Physical Systems (CPS), augmented reality, gaming, computer-mediated social interaction, and the like. These applications are highly interactive, data intensive, and distributed, often involving extremely sensitive societal and personal information.SERECA is validating its results through the development of two innovative and challenging industry-led use cases. One concerns the monitoring of a civil water supply network, a critical infrastructure targeted by malicious attacks. The other concerns a commercial software-as-a-service (SaaS) application for analysing the performance of cloud-deployed applications. Such a service collects sensitive perf
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'smARt Monitoring Of distribUtion netwoRks for robust power quality' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

General awareness about the smart grid technologies has improved in the last decade due to various energy liberalization actions taken by the European Union. However, the lack of well-developed technologies, has been main cause of slow acceptance of smart grids. This calls for the identification of unexplored research areas in smart grids. Positive outcomes of the research can help in laying down new and well-defined standards for the smart grids and associated intelligent technologies. A convenient and easily integrable product can also help in encouraging various distribution system operators to accept the new technologies. Massive amount of data is already being collected from the distribution networks using smart meters. Rapid advancements in machine learning research have opened up new avenues for data utilization in smart grid. Forerunners like DEPsys (a smart grid technology company based in Switzerland), have now simplified the distribution system data for further analysis and research. A critical concern raised by DEPsys customers, is their inability to trace the source of power quality issues in the distribution network, which in-turn leads to both energy and economic losses over time. This project builds up on existing infrastructure of DEPsys and aims to be an AMROUR (by improving robustness) for distribution networks against power quality events. The main objectives are: (i) leveraging machine learning for condition monitoring and tracing power quality events, and (ii) to develop a smart grid technology which assists the distribution system operators in prevention and diagnosis of power quality events.


**Keywords:** Smart grids, Power quality, Power distribution networks, Machine learning, Signal Processing, GridEye, Condition monitoring, Detection, Predi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Probing and controlling the three-dimensional organoid mechanobiology' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Interaction between cells and their mechanical microenvironment plays a key role in the regulation of development, physiology and disease. Cell behaviour is also regulated by the dimensionality of the microenvironment: 2D cultures displaybiological traits that generally differ from those of 3D tissues, thus limiting their potential in biomedical research. Thislimitation has been addressed by the recent development of Organoids, which faithfully preserve a number of distinctivetissue traits. Still, current biophysical tools and conceptual frameworks are not yet suitable to probe and understand themechanobiology of 3D organoid systems.This project aims to study and manipulate the mechanobiology of normal gut and colorectal cancer organoids. We willdevelop tools to quantify the 3D stresses applied by an organoid embedded in a gel. By measuring its 3D surface stressesand Young’s modulus we will quantify its interstitial pressure and contractility, key parameters in organ growth and tumourprogression.Pressure and contractility will be related with key biological parameters such as geometry, cell adhesion and proliferation.We will fluorescently tag proteins in the organoids that will allow us to track individual cells, as well as monitoring theirpolarization and adhesion. The relationship between mechanics, geometry, and cell function will be further assessed bychemically reducing proliferation, mechanical stresses and adhesion.We will also modify the mechanical state of the organoids through optogenetic means. We will express proteins in the cellsto control Rho-GTPases upon illumination, thereby steering the local stresses at will. We will modify organoid pressure,contractility and geometry and study their influence on the phenotype.As organoids emerge as novel tools in biom
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Integrated Sensing Architectures and Tools for Health Care'.

assistant: **Concept**

This proposal addresses high-risk, high-reward research of integrated sensing and computing architectures, as well as of models, methods and tools for their design and operation. Such architectures provide the bridge between bio-systems and information processing systems, where a bio-system is an abstraction of a human in terms of biophysical parameters. Breakthroughs in data acquisition, processing and decision making support will enable new smart-health applications.The essential research goals of this proposal are: biophysical data acquisition by novel programmable integrated sensor arrays and their design and test using a modular and structured architecture; data processing in situ and/or remotely using application-specific hardware and/or embedded software; a new robust synthesis methodology for data processing units based on a new logic structure; models, abstractions and software tools for reasoning about the acquired data, to validate health conditions and/or to provide remedies (i.e., therapy). The results of this research will be embodied in a demonstrator showing the effectiveness of these combined technologies in first-aid medical care. The outcome of this research will have a deep and broad impact on health care, because it will improve diagnosis and therapy in a variety of cases. Namely, it will boost the quality and quantity of the acquired biophysical data, possibly in real time, by leveraging multiple sensing modalities and dedicated computing architectures. The use of formal methods for design, data evaluation and decision making support will enhance the quality of the diagnostic platforms and will ease their qualification and adoption. Moreover, the integration of sensing and electronics and their in-field programmability will reduce production cost a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Neural Mechanisms of Visual Perception and Attention' (NEURO-VPA) targeting Seventh Framework.

assistant: **Abstract**

Attention is a control system that optimizes behavior by altering the way that incoming sensory information is processed. Determining how attention influences the way that information is represented throughout the brain is a core problem in sensory neuroscience. Recent evidence from primates suggests that attention can change tuning in single neurons at higher stages of visual processing. Tuning changes imply that many visual representations are not fixed, but rather can be changed dynamically according to task demands. However, it is currently unknown whether attention causes tuning changes in the human brain.This proposal investigates how attention changes tuning for a broad range of semantic features across the entire human brain. To address this issue, the proposal uses functional MRI to record blood-oxygen level-dependent (BOLD) signals while humans search for specific object or action categories (e.g., “Humans” or “Vehicles”) in natural movies. The proposal leverages an innovative voxel-wise modeling framework to characterize how attention changes tuning for hundreds of semantic features. This framework will enable separate characterization of attentional influences on response baseline, response gain and tuning.The proposal consists of two broad Aims. Aim 1 focuses on how attention changes the way that objects and actions are represented in the brain. Aim 2 addresses the computational principles that govern attentional tuning changes. These experiments will provide crucial information for understanding how the brain dynamically changes representations to optimize behavior during natural vision, and they will provide the first quantitative semantic models that accurately predict BOLD responses during natural visual search. The results will advance our understandin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'INtegration of technological Solutions for Imaging, Detection, and Digitisation of hidden Elements in artworks'.

assistant: **Innovation**

Because cultural heritage is one of the most valuable assets of our continent, European institutions are strongly committed with its conservation and protection, but also with its worldwide diffusion through the utilisation of digital technologies. In this context, we present INSIDDE (INtegration of cost-effective Solutions for Imaging, Detection, and Digitisation of hidden Elements in paintings) project as an innovative solution for capturing, imaging, and digitising unknown details of paintings and 3D artworks by means of terahertz technology in a unique approach, with the purpose of going beyond our present knowledge and adding value to the cultural content.A versatile, easy to configure and affordable prototype – working in different frequency bands within the THz region –  will provide a complete set of images of the paintings and sealed objects, revealing complementary information about its hidden features – such as underlying contents, pigment/substance identification, brushstroke texture, defects  – through various processing techniques.The resulting enriched images and 3D models will be exploited in two manners: integrating them into the professional knowledge-sharing platform Europeana and developing an innovative smartphone application based on Augmented Reality.Although curators and art researches will benefit from our works, the key of INSIDDE lies in improving the experience of visitors at European museums and through the internet by increasing the digital resources at their disposal, leading to a more attractive interaction.Experts from academia, technological research centres, SMEs and end-users with large experience collaborating in international research projects constitute a well-balanced consortium, in which the participation of museums definitely pl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Smart nondimensional biosensors for detection of tumor cells and cytotoxic amyloids intermediates'.

assistant: **Innovation**

This project integrates the development of (a) bioconjugated silicon nanoparticles (NPs) as new, < 3nm, fluorescent probes and (b) dual-emission band fluorescent biosensors for protein conformation investigations to be applied in diagnostic procedures related to tumor biology and neurodegenerative diseases. Epidermal growth factor receptor (EGFR) is an important therapeutic target in a variety of tumors, particularly malignant gliomas where mutation and/or amplification of EGFR is often observed. The laboratory has demonstrated in a pilot study the specific binding of biomolecules conjugated to Quantum Dots to patient-derived glioma spheroids.  High wavelength emitting QDs are necessary to distinguish binding from tissue autofluorescence but such QDs are large (~40 nm) and do not penetrate deeply into tissues or access cellular junctions.  The project will develop smaller, more inert, and less toxic conjugated silicon nanoparticles that can ultimately be used for the detection of residual glioma cells in patients after surgical resection. Additionally, more complex composite nanoparticles that selectively internalize in the tumor cells will be investigated as vehicles for drug delivery or selective killing. The aggregation of proteins and peptides is a fundamental feature of neurodegenerative diseases such as Alzheimer’s, Parkinson’s and spongiform encephalopathies. It is not clear whether the fibrillar aggregates or smaller forms of the implicated proteins are the cause of cytotoxicity. Both in vitro assays and in vivo studies are hampered by the lack of probes that can distinguish and quantitate early stages of the aggregation phenomenon. This project will develop fluorescent biosensors for protein folding on the basis of environment sensitive ratiometric dyes that ex
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Cross-border commuting in the eu: obstacles and barriers' under Fifth Framework.

assistant: **Concept**

The EU has recently stressed the importance of policies aimed at reducing barriers to mobility across member states in the EU. This Accompanying Measure combines state-of-the art surveys in six EU member states with a feasibility study in preparation for a major comparative research project on barriers to cross-border commuting. It will enable an existing network of researchers to identify, collect and discuss information about factors which inhibit cross-border commuting in the EU as perceived by European citizens . This will be achieved thorough three workshops, surveys of recent research in the area, and pilot interviews in four border regions. The Measure will be of relevance to policy makers and organisations (e.g. EURES). The dissemination includes a website, the participation of experts and policy makers in the workshops and the preparation of publications.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Preferences for Intervention and Prevention among Ultra- Orthodox Jewish Women Effected by IPV: An In-Depth Examination' under Horizon 2020.

assistant: **Concept**

The phenomenon of Intimate Partner Violence (IPV) knows no boundaries. It crosses all sectors, cultures, countries and groups of ages. Recently we can see major interest in the study of IPV among ethnic groups, neglected minorities, as well as among faith-based communities. The aim of this individual fellowship is to explore IPV in terms of seeking care among abused ultraorthodox Jewish women (UOJW). In other words, the purpose of the planned study is to explore preferences for intervention and prevention among UOJW effected by IPV (IPUOIPV). Based on 30 semi-structured face to face interviews and 5 focus groups of women with prior or current experience of IPV, from the Ultra-Orthodox communities in Montréal and Israel, the aim of this study is to gain a better understanding of the specific needs of this minority in relation to IPV. Such study can contribute to practice and future research examining IPV in other minorities, communities-based faith, and hard-to-access populations around Europe and worldwide.  For decades, IPV was known as a hidden problem in the Orthodox Jewish communities. However, only recently it is acknowledged to occur in Orthodox Jewish families. Alongside the unique difficulties of abused women, UOJW display several cultural characteristics that require solutions to ensure their social well-being, due to their conservative and obliging way of life. In addition to the common types of IPV (physical, emotional, sexual, economic and social), UOJW may also suffer from spiritual abuse. An example of spiritual abuse might be, when a husband forces his wife to pray against her will, or to avoid intimacy after she is going to the 'Mikveh' (religious immersion-bath).This study may reveal an added value to the current state of the art in the field of IPV. It