RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'NanoMembranes against Global Warming' (NANOGLOWA).

assistant: **Innovation**

The ultimate way to reduce CO2 emissions as required by the Kyoto protocol from the main contributors, the fossil fired power stations, is by CO2 capture. Existing methods (adsorption, non selective cooling) are not very cost- and energy effective: up to 25% consumption of the produced energy. CO2 separation through membranes will consume much less energy (8%), but suitable, reliable and economical membranes are currently non-existing. The objective is to develop optimal nanostructured membranes and installations for CO2 capture from power plants below 20 euro/ton with a build-in, smart, diagnostic technique. The consortium of 26 partners including 7 SMEs involves 14 countries. Five innovative membrane materials will be developed simultaneously.The project organisation will stimulate cross-fertilisation for achieving major breakthroughs. For this an integration, modelling and a diagnostics task is included and cooperation with and field-testing by 6 future end-users will guarantee the realistic outcome of the material research. The cost price for the membranes will be a factor 5 lower by increasing the performance through radical innovations in membrane technology: a spin-coated sub-micron layer, oriented nano-spurs with active groups through the layer of the membrane and inherent oxygen stability by the introduction of active groups as block-copolymers in the membrane backbone. Smart design modules, for long life, low degradation and contamination combined with integrated performance monitoring, will be developed and tested in the laboratory and in the field.Dissemination and exploitation strategies are incorporated in this project by including the mayor EU electricity companies and their equipment suppliers. Training activities and workshop s on membrane development a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Genetic determinism of maritime pine pulp and paper properties'.

assistant: **Innovation**

Natural populations of Maritime pine trees show large, in part genetically determined, variations in the properties of lignocellulosic fibres and the derived pulp and paper products. So far, tree breeding programs have failed to exploit this variation, due to the costly and destructive traditional chemical and technological assays and the requirement for mature trees to evaluate such lproperties. In this multi-disciplinary project, we propose to solve this problem starting from two angles. First, we will use and further develop reliable, fast, lcheap and non-destructive selection criteria for pulp and paper properties. Second, we will use a combination of QTL mapping, global gene expression analysis, Arabidopsis genomics and linkage disequilibrium mapping to identify the genes controlling the traits underlying the natural variation in pulp and paper properties. This should yield valuable criteria for the selection of elite trees.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'THE PROBABILISTIC CONSTRUAL OF MODALITY' (PCM) under Seventh Framework.

assistant: **Objectives**

The project concerns the semantics of modal expressions in language, and in particular modal verbs such as 'might', 'must' and 'can'. The hypothesis under investigation is the Probabilistic Construal of Modality, stating that modal verbs like the above should be given a semantic analysis in terms of (among other things) probability functions. This is a very active topic of research within philosophy and linguistic semantics, which is generating a large amount of literature. The project will improve on the state of the art in this literature in four respects. First, it will clarify the basic question, outlining explicitly the methodology for a systematic study of the PCM hypothesis. Second, it will undertake a systematic investigation of the compositional interactions of modals and other operators in language. Third, it will draw much needed conceptual connections between the semantics of modality and probabilistic models of belief. Finally, it will revisit important classical literature on the connection between probabilities of conditional statements and conditional probabilities.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Role of rab5-rabgdi in clathrin-coated vesicle formation' (1994-1998).

assistant: **Innovation**

Research objectives and content Clathrin-coated vesicle formation leads to the receptor-mediated endocytosis of extracellular macromolecules. The mechanism which regulates the formation of such vesicles is poorly understood. Clathrin, adaptors, ATP and cytosol are all required for the formation of these vesicles. One of the cytosolic components required for coated pit invagination has been identified as rab5-rabGDI, a component previously demonstrated to be important for membrane dynamics at later stages of the endocytic pathway. The processes of transport vesicle formation and subsequent fusion therefore appear to be linked. The aim of this project is to further define the role of rab5 in clathrin-coated pit formation using biochemical and morphological approaches. These studies should yield valuable information, not only about the mechanism of clathrin coated pit assembly but may also have implications for other vesicle trafficking pathways. Training content (objective, benefit and expected impact) Only limited data are available on the regulation of clathrin-coated vesicle formation . This project will lead to a better understanding of this mechanism in elucidating the function of rab5 and interacting proteins. This will ultimately help propose a model for the formation of the clathrin-coated vesicles. This project will provide training in addressing essential question in cell biology using multidisciplinary approach. Links with industry / industrial relevance (22) The research carried out in the host laboratory is basic research into an essential cellular mechanism. At the moment there are no links with industry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Multimodal Imaging of Disorders of Consciousness' (MIDOC) under Horizon 2020.

assistant: **Objectives**

The diagnosis of individuals with disorders of consciousness has fundamental implications in terms of prognosis, treatment, palliative care and even proper end-of-life decisions. Diagnosis based on behavioural assessment is difficult and it is believed that misdiagnosis occurs in a large percentage of cases (> 40%). Non-invasive functional brain imaging has recently emerged as a promising tool for the diagnosis of individuals with disorders of consciousness; however, different imaging methods allow descriptions at limited spatial and temporal resolutions, and it is unknown how these findings relate to each other, to the underlying brain anatomy, and whether they are manifestations of a single fundamental mechanism underlying the impairment of conscious awareness. The proposed research project aims to investigate individuals with disorders of consciousness by simultaneously applying these different neuroimaging techniques, thus integrating neurophysiological data across description levels and evaluating their synergy for the objective diagnosis and prognosis of patients. We address the hypotheses that alterations in brain rhythms (measured with electroencephalography) typical of individuals with disorders of consciousness (such as the emergence of low-complexity and low-frequency neural oscillations) are related to diminished fronto-parietal activity and a breakdown of thalamo-cortical functional and anatomical connectivity (functional magnetic resonance imaging; diffusion tensor imaging) and that these signatures of consciousness correlate with the severity of the disorder and the degree of conscious awareness of the patients. In addition, we are proposing a career development plan for the applicant that includes training on scientific and transferable skills. This plan
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Natural killer T cells (NK-T) immunoregulation by VIP: functional analysis, mechanisms of action and effects on type 1 diabetes as a model of Th1 type autoimmnune disease'.

assistant: **Concept**

The immune system and the brain continuously signal each other, often along the same pathways, which may explain the connection between immunity, mind and disease. Part of this communication network is represented by neuropeptides and their receptors and recent findings can now address the issue of relevance to health, proving a potentially profound clinical significance.The vasoactive intestinal peptide (VIP) is a neuropeptide synthesized by immune cells that functionally has various characteristics to be considered as a possible therapeutic agent for Th1 driven diseases with inflammatory and autoimmune components. Immuno-mediated (type 1) diabetes is an incurable disease that is increasingly in incidence throughout the Western world. The discovery of Th1 and Th2 subsets has helped to explain the immunological basis for the diversity of T cell responses in autoimmune diseases such as type I diabetes. VIP is a potent anti-inflammatory agent, which regulates a broad spectrum of pro-inflammatory factors synthesized by both activated macrophages and microglia. Following antigenic stimulation, VIP is able to shift a Th1 immune response to a Th2 response.The therapeutic effect of VIP on a model of rheumatoid arthritis and Crohn's disease, two inflammatory and Th1-mediated autoimmune diseases, demonstrates its efficacy to treat this kind of disorders. In this study, by using the principal and a well-established animal model (Non Obese Diabetic) for type I diabetes, we will asses the role of VIP as a candidate to modulate the onset of type I diabetes. Besides that, we will gather data about the cellular and molecular mechanisms involved in VIP-mediated immunomodulation on Natural Killer T (NK-T) cells and other regulatory T cells. The results are interesting to test th e endog
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Training network on tRAcking in compleX sensor systems' (TRAX) under Seventh Framework.

assistant: **Objectives**

In today’s society, massive amounts of electronic sensors surround us that are tracking objects for the purpose of healthcare, surveillance, retail oriented commercial purposes and many others. Modern sensors generate very large amounts of data, however, due to current technical limitations, it is nearly impossible to integrate large scale data from many different and complex sensors to track very large groups of objects and people. Major advancements in various important areas in our society, such as traffic and crowd management, movement science in healthcare, smart surveillance, security and defense are hindered by this limitation, slowing down European industrial growth. The Training programme on Tracking in Complex Sensor Systems (TRAX) project aims to investigate and design innovative algorithms and techniques for dealing with raw data from complex and advanced tracking systems. This will be achieved through the establishment of a novel research training programme on Tracking in Complex Sensor Systems, covering interdisciplinary and intersectoral aspects in this newly emerging supra-disciplinary field. The TRAX consortium comprises two large companies (Thales Nederland B.V., Ericsson A.B.); two SMEs (Rinicom Limited, Xsens Technologies B.V.); a research institute ( Fraunhofer) and three universities (University of Lancaster, Linköping University and University of Twente); and is supported by two associated partners: SME SenionLab A.B. and University of Bonn. 12 early stage researches and 3 experienced researchers get the opportunity to work on the state-of-the-art complex tracking field. The uniqueness of TRAX is that while all research is being performed under one umbrella, it is being exploited by different branches of industry and implemented in various applica
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'European network supporting infrastructures for arctic charr culture and conservation (CHARRNET)'.

assistant: **Concept**

CHARRNET - The proposal will lead to the formation of a unique Network of Research Infra-structures involving Arctic char in Europe. The Network will include Academic and Commercial research Infrastructures, together with potential users and conservation interests. The Network will operate at International level, with National gateways, and will include a strong internet presence. The Network will lead to the production of a manual of Protocols and best practice within such Infrastructures at a European level. The project will also stimulate more access by researchers to the Infrastructures.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Reinforcing FLEXibility of SMEs by dynamic business process management'.

assistant: **Objectives**

Achieving business flexibility is a necessary condition for the business development of SMEs, especially nowadays due to the global market downstream. The business flexibility implies flexibility in the underlying ICT infrastructure and business processes. Moreover, in the current climate, midsize organizations also need to achieve flexibility in an affordable way, since in the current economic climate, organizations are under pressure to freeze expenditure and wring ever more return from existing assets.Business process management (BPM) is a class of software which directly contribute to enterprise performance by driving operational excellence and business flexibility. However, current solutions for BPM are tailored to the need of big companies, are quite expensive and drive mainly technology flexibility and not necessarily business flexibility.ReFLEX aims at strengthening the competitiveness of the SME participants by developing a new BPM model tailored to the need of SMEs for being continuously aware of the changes in the environment and to change/adapt themselves accordingly in order to keep the business process running well. Indeed, in that way SMEs will increase their responsiveness on the new business opportunities (or threats) which is a crucial feature for the business development (even survival) for small fishes in big oceans of the globalized economy.However, in order to realize the dynamic BPM, a substantial research on the new model for the description of (ad-hoc) dynamic business processes is needed. This includes the development of a novel workflow engine that will be able to execute such processes as well as the calculation of changes on the fly. ReFLEX aims to perform this research in order to develop, deploy, validate and exploit such an approach for t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'European Vascular Genomics Network' (EVGN).

assistant: **Concept**

Cardiovascular diseases (CVD) caused 51% of deaths in Europe in 2001.Coronary heart disease and stroke, which result from atherosclerosis, constitute 80% of CVD. Better prevention and treatments have halved age-specific incidence, but the ageing population and adverse trends in obesity and diabetes threaten these improvements. There is also an alarming increase in heart failure, the end stage of coronary heart disease. Future advances depend on developing entirely new strategies. Genomics and proteomics together complete human genome open up fresh horizons for molecular understanding of cardiovascular disease, for identifying new diagnostic measurements and developing new pharmacological, gene and cell-based therapies. The European Vascular Genomics Network (EVGN) assembles the necessary critical mass and promotes multidisciplinary interactions by uniting 25 world-leading basic and clinical institutions from 9 European countries. It focusses on the three areas with greatest therapeutic potential: 1) endothelial dysfunction, an early critical event in atherosclerosis and hence a target for prevention, 2) plaque instability, responsible for precipitating thrombosis and hence most life-threatening acute events, and 3) therapeutic angiogenesis either conventional or cell-based to recover ischaemic organ function and reduce heart failure. Our research armoury spans genomics, proteomics, molecular biology, cell biology, gene transfer and genetic modification in mice, and integrative pathophysiology in man. The EVGN will maximize the scientific and commercial potential of European vascular biology by electronic data-sharing and communication networks, shared research tools, and exchange and training programmes. The EVGN will train tomorrow's lead investigators through a Europe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Isolation of medicago genes involved in the nod signal transduction pathway and nodule organogenesis' to be submitted under Fourth Framework.

assistant: **Abstract**

Nodule organogenesis is triggered by the bacterial Nod signal molecule the Rhizobium-legume symbiosis. Plant early induced genes participating in the Nod signalling cascade are most likely of low abundance and therefore, have been difficult to identify by usual cDNA libraries which have allowed cloning of the most abundant mRNAs. To overcome this limitation, we will then use the differential display retrotranscriptase PCR technique that allows to separate and clone individual mRNAs by means of the sensitive PCR reaction. On the basis of the facts tha. early nodulins can be induced by cytokinins we will compare the RNA populations derived from Medicago roots treated with either active or inactive Nod factor to those treated with cytokinin. Amplified cDNA fragments corresponding to differentially expressed mRNAs are shown to be will be analysed by sequencing and identification of full length genes in the Medicago cDNA or genomic library.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Production of tensioactives from oleaginous plants fatty chains and polysaccharides from ulva sp.'.

assistant: **Objectives**

Summer mass blooms of macroalgae have been occurring increasingly for two decades along the Mediterranean, French Atlantic and Baltic coaltline. The principal responsible is a chlorophyta of the genus Ulva. The green tides" phenomenon becomes a major environmental problem on the European coasts. In France, on the coasts of Brittany, 100 000 m3 of green seaweeds are collected yearly from the beaches. In Italy, during the period between 1989 and 1991, an area of 65 km2 in the Venice bay way covered with Ulvarigida. The elimination of the green algae generate Immeasurable costs for the coastal townships. An another environmental problem is the use of tensio-actives by the detergent industry. This detergents have to be biodegradable according the European regulations. The purpose of the project is to synthesize new biodegrable tensio-actives from Ulva polysaccharides and oleaginous fatty chains. This new surfactants will find an application in the detergent industry."