RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Nanocrystallite architecture - preparation & characterisation of nanochrystalline semiconductor arrays' (1994-1998).

assistant: **Innovation**

Use of sensitised transparent nanocrystalline metal oxide semiconductor films as photoanodes in regenerative photoelectrochemical cells has attracted considerable attention. Other reported applications for nanocrystalline metal oxide semiconductor films include prototype lithium insertion batteries and electrochromic windows. In addition applications in the areas of photosynthesis and photodegradation of organic materials are also foreseen. In short, nanocrystalline metal oxide semiconductor films are increasing in technological importance. Consequently significant effort is being directed towards the development of improved methods of preparation and characterisation of nanocrystalline metal oxide semiconductor films. To-date, however, relatively little effort has been directed towards controlling the morphology of such films. Specifically, while significant progress in characterising the porosity, thickness and distribution of adsorbates within such films has been reported, active control of the above has yet to be achieved. Proposed here is a programme of research leading to the preparation of transparent nanocrystallline metal oxide semiconductor films possessing a desired morphology. Specifically, efforts will be directed towards development of methods which can be used to prepare one, two and three dimensional supported and unsupported nanocrystalline films with varying degrees of ordering. Much of the subsequent applied research is preformed in collaboration with industrial partners and is ultimately directed at developing prototype solar energy conversion smart window and optical information storage tchnologies. Currently the host laboratory is laboratory is collaborating with Donnelly mirrors (Ireland) Ltd. and Hewlett-Packard ( Ireland ) Ltd. in each of these
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Turn Cancer Immunotherapy Effective in Most Patients'.

assistant: **Concept**

Stimunity is a company that develops disruptive immuno-stimulatory biological drugs to restore the immune system against tumor cells.Immune checkpoint inhibitors showed great potential in cancer immunotherapy after achieving 5-year survival rates for patients with advanced or metastatic cancers, unseen by physicians before. This is a promising beginning. Nevertheless, 5 million patients worldwide remain unresponsive to immunotherapy and do not have any other therapeutic option. On average it represents 50% of all cancers.A promising answer to this problem is the development of new drugs that activate the STING (STimulator of INterferon Genes) pathway, which fires up the innate immune system of these unresponsive patients, inducing a potent and durable anti-tumour immune response. It is expected to be effective on a much larger number of cancer patients.Stimunity’s first product, named STI-001, restores weakened immune systems to kill tumour cells. It is especially effective on distant tumours. Competitors using chemical STING ligands have shown a much weaker immune response than STI-001. STI-001 is based on a safe cutting-edge Virus-Like Particle (VLP) technology that encapsulates the best-known natural STING ligand and efficiently deliver it into immune cells.There is high interest in STI-001, as demonstrated by public and private funding (raised €2.2M to date) and advanced discussions with major pharmaceutical companies (see Letters of Intent).SMEi1 project will allow Stimunity to i) confirm the technical feasibility of manufacturing STI-001, (ii) update the FTO, (iii) assess regulatory issues, (iv) validate the marketing and business plan.Our long-term goal is to develop a pipeline of products based on proprietary VLPs in cancer immunotherapy and create a long term o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'MARPERWISE: Submarine permafrost and seafloor geomorphic change in the Canadian Beaufort Sea' (MARPERWISE) targeting Horizon Europe.

assistant: **Abstract**

Submarine permafrost, a vital component of the Arctic environment, plays a significant role in geological and environmental processes. However, critical knowledge gaps persist, necessitating comprehensive investigations. Our project, 'MANPERWISE,' seeks to address these gaps and enhance our understanding of this dynamic phenomenon. Despite advancements, uncertainties surround the extent, thickness, and degradation of submarine permafrost in the Arctic. 'MANPERWISE' aims to quantify these aspects within a designated study area, employing a state-of-the-art controlled-source electromagnetic (CSEM) system developed by the University of Malta. One key objective is to unravel the intricate relationship between permafrost degradation and seafloor geomorphic changes, with a specific focus on seafloor instability. By analysing data acquired through our CSEM system and comparing it with seafloor morphology, we aim to elucidate the mechanisms driving these transformations. Furthermore, 'MANPERWISE' envisions the development of a conceptual design for a Remotely Operated Vehicle (ROV)-based or Autonomous Underwater Vehicles (AUVs)-based CSEM instrument. This advanced tool will enable high-resolution, repeat mapping of submarine permafrost and Submarine Groundwater Discharge (SGD). Such innovation promises transformative insights into the Arctic's evolving dynamics. Dissemination efforts encompass scientific publications, research conferences, seminars, a dedicated project website, and engagement with policy-makers and the general public. Guided by Prof. Charles K. Paull (MBARI), Prof. Aaron Micallef (University of Malta), and Prof. Mark Everett (Texas A&M University), ‘MANPERWISE’ addresses critical knowledge gaps in submarine permafrost dynamics, offering insights with implicatio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Spectroscopy of ordered and quasi ordered complex solids' (SOQCS), addressing dissemination and exploitation.

assistant: **Impact**

Complex oxides with competing interactions are one of the biggest challenges in condensed matter physics and at the same time promising materials for applications.  The recent developments in ARPES (angle-resolved photoemission spectroscopy) studies of cuprates opens a direct window on how strong correlations renormalize energy bands, and may provide important clues into the unusual properties of these materials.  The proposed research will combine the Guest's expertise in modeling complex oxide spectroscopies (ARPES, RIXS -- resonant inelastic x-ray scattering) via a weak coupling route (Hartree-Fock to RPA to self-consistent Born approximation -- SCBA) with the Host's strong coupling expertise (time-dependent Gutzwiller approximation -- TDGA) to provide a deeper understanding of cuprate physics.  In particular, electron-doped cuprates have been modeled as uniform antiferromagnetic superconductors, with renormalized hopping parameters (with respect to first-principles LDA calculations) and a doping dependent Hubbard U.  We hope to explain the renormalization via SCBA and the doping dependence of U via TDGA.  The same model, with similar parameters, should apply to hole-overdoped cuprates.  We will use TDGA to generate stripe physics, to extend the model to the hole-underdoped (pseudogap) regime.    Extensions to other systems (metallic nickel) will also be undertaken.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Deciphering the microglia-neuron interactions in human Alzheimer's disease', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The goal of this project is to decipher the exact cellular and molecular mechanisms by which human microglia transduce toxicity to neurons in Alzheimer's disease (AD). Genetics revealed that microglia are one of the central players in the pathogenesis of AD. I and others have characterized the phenotypic response of microglia in AD using transcriptomic and epigenetic tools. Nevertheless, it is yet to be defined how microglia communicate with other cells in the brain, by which mechanism they lead to neuronal alterations, and what the particular role of different microglial activation states is in this process. I will investigate the two major functional outputs of microglia - namely physical interaction with synapses and release of inflammatory factors that induce neuronal dysfunction and degeneration - in AD. Determining the role of human microglia in AD comes with technical challenges, including lack of homology between mouse and humans, and limited expression of AD risk genes in mouse microglia. I will use a human microglia xenograft model I pioneered where iPSC-derived cells are transplanted into the mouse brain, and in which they adopt a brain resident phenotype and can be exposed to amyloid-b plaques. I plan to combine xenotransplantation of genetically engineered iPSC-derived microglia and neurons, with state-of-the-art strategies to define the human microglia-synapse protein interactome as well as the cell-specific proteome/secretome. I aim to 1) define the surface protein interactome between human microglia and mouse synapses in vivo, 2) co-transplant human microglia and human neurons in the mouse brain to explore human to human specific aspects of this interaction, and 3) investigate the human microglia specific secretome in AD. This project will be the first o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'SW/HW extensions for virtualized heterogeneous multicore platforms' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

Embedded devices are pervasive in our everyday live and their complexity increases exponentially. Among them, heterogeneous multi-core processors and specific hardware accelerators allow the required computing power while exhibiting a good performance/watt ratio. The flexibility required by them is promoting an application-centric model, which makes future systems face new challenges: Openness (total decoupling from hardware to application software), security, programmability and performance.Virtualization, widely used in the general-purpose computing domain, allows an effective and clean way to isolate applications from hardware, so being suitable to cope with the challenges faced by heterogeneous multi-core embedded systems. However, virtualization on embedded systems is still in its infancy. Their real-time requirements, resource constraints and heterogeneous nature demand for an integral and different approach of the virtualization concept. The vIrtical project aims the vertical and full development of the virtualization concept addressing the specific requirements for effective embedded virtualization. A virtualization-ready SoC platform and the associated programming models will be developed, tackling all the system layers: applications, programming model, hypervisor and hardware. This unique integrated approach is able to address the evolution towards heterogeneous multi-cores and even many-cores in embedded systems by focusing not only on the well-known processor virtualization but on the hardware assisted virtualization for the overall SoC. Security and protection, real-time QoS guarantees, reliability, process variation, power savings, and memory coherency will be addressed and will influence the way the system is virtualized.The vIrtical consortium is formed
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The medicine of the mind and natural philosophy in early modern England: A new interpretation of Francis Bacon' (MOM).

assistant: **Concept**

The aim of the project is to provide a groundbreaking new interpretation of Francis Bacon's natural philosophy. The original aspect of this project will consist in a new contextualisation of Bacon's philosophy. We argue that his work can be seen as one of the most characteristic products of what we have decided to call, for reasons of heuristic and exegetical convenience, the medicine of the mind. This project is interdisciplinary in both the method we are going to apply and the object we are going to study, for this investigation represents a study on early-modern interdisciplinarity. The movement known as Renaissance Neostoicism, especially in its French version, will be a key element in our argument. The objectives of the project are, first, to provide an unconventional interpretative angle to the study of the transmission of Stoic ideas; second, to show their intertwinement with religious models of self-analysis and, most of all, to highlight the combined influence of Stoic and Reformed models of introspection on Bacon's natural philosophy. We argue that Stoic materialism, from its inception, entailed the view that human appetites could not be explained and tamed without connecting them to the very appetites of nature. Our reconstruction of varieties of British medicine of the mind, permeated by Stoic ideas, will throw much needed light on the way in which Bacon looked for a new method that could allow man to master both the appetites of matter and the appetites of society. In more general terms, our reconstruction of the British contexts of the medicine of the mind will provide a crucial missing link in the contemporary narratives of the scientific revolution.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Technologies for Optimising the Precision of MS-WIM of Road Transports to Improve Automatic Overload Control and European Procedures for Enforcement' in the context of a Fifth Framework call.

assistant: **Objectives**

Future improvements for Traffic Monitoring and Control are urgently necessary to achieve higher safety and economy on the European motorway network. Better and fair control of heavy goods transportation must be solved on European scale. 4 countries are joining this trial with users, industry and administrations to test new WIM technologies to reduce the impact of overloaded heavy goods vehicles on the road safety and to limit the serious damage caused on road infrastructure with tremendous repair costs, by investigating and optimising technical and administrative solutions. The TOP TRIAL project will last 23 months, will build up the necessary complex test site, will perform trials for 1 year with multi sensors and algorithms, will optimise accuracy for enforcement and will propose new procedures for overload control. Results will be an improvement in the accurate measurement of WIM arrays, a draft of future European standards for overload enforcement and dissemination to users.Objectives:Using WIM systems up to now allows only the monitoring of overloads on motorway lanes and in secondly permits the police to guide the overloaded truck to a separate approved slow motion axle weighbridge located on a parking place or to a static weighbridge. Efficient automatic overload enforcement with a high detection rate is particularly necessary to enforce the legal regulations and to guarantee fair competition between various transport modes and transport companies. The global objective of TOP TRIAL is to improve procedures and technologies for higher traffic safety and road protection by testing them for enforcement of overloaded freight transport. This project aims to achieve greater accuracy of the WIM systems in a trial allowing investigations of staggered multi sensor arrays
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'In Space Propulsion 1' (ISP-1) targeting Seventh Framework.

assistant: **Abstract**

In Space Propulsion 1 was set up to improve the fundamental knowledge and the techniques which are necessary to allow Europe to implement new ambitious space programs involving cryogenic propulsion. It concentrates on liquid oxygen, liquid hydrogen, and liquid methane propellants, and the anticipated progress will address - LOX methane combustion - heat and propellant management - materials tribology, compatibility, and hydrogen embrittlement.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Enabling the transferability of cycling innovations and assessment of its implications'.

assistant: **Innovation**

HANDSHAKE supports the effective take up of the integrated cycling solutions successfully developed by Amsterdam, Copenhagen and Munich, our Cycling Capitals and world-renowned cycling front runners, to our 10 highly committed Future Cycling Capitals, Bordeaux Metropole, Bruges, Cadiz, Dublin, Helsinki, Krakow, Greater Manchester, Riga, Rome and Turin. Our partner cities are combined in a composite working environment in which diverse geographical contexts, socio-economic conditions and planning cultures work toward the same goals, that is, delivering the desired cycling change. The project believes that effective transfer can happen only in the presence of: i) state-of-art body of knowledge on cycling policy and solutions; ii) sustaining transition processes; iii) motivating and supporting forms of mentorship. In HANDSHAKE this is ensured by the presence of 3 cycling planning champions, the employment of highly innovative methods brought together into a supportive and novel transfer cycle (including Bikenomics, Immersive Study Tours and Transition Management), and a mentorship programme that takes by the hand each participating city. The gathered team will cooperate to reach a number of strategic objectives: i) Inspire the creation or refinement of holistic cycling visions and concrete transfer approaches; ii) Foster the adoption of a multidisciplinary planning culture to empower the project process and consolidate future cycling policies and investments; iii) allow cycling to become a key element of urban transport; iv) Improve cycling modal share and safety; v) Leverage the potential of cycling as a critical congestion relief tool; vi) Leverage cycling to improve public health; vii) Foster economic growth. HANDSHAKE expects to improve cycling attractiveness by +52% a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'AntifragiCity' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

The growing motorization in our cities has led to an increase in traffic congestion, noise, pollution, carbon emissions and concerns about road safety, resulting in social, environmental, and economic consequences. AntifragiCity’s overall aim is to pave the way to a new urban mobility governance approach that enables cities to understand their business-as-usual modus-operandi (defined as their state of equilibrium) and to monitor (near) real-time continuous stressors and deviations from this state, assess potential implications through simulation and prediction capabilities, evaluate mobility triage scenario public acceptability and justice, and inform adapted decision making to mitigate their consequences, while continuously enhancing sustainability and resilience. AntifragiCity will pave the way to antifragile mobility urban systems that (a) exploit an adapted framework and associated KPIs to continuously monitor the level of resilience of urban mobility and detect (near) real-time potential stressors; (b) characterize these stressors as well as their level of severity thanks to an event ontology; (c) devise adapted short-term responses based on a mobility triage decision support system; (d) simulate and analyse multi-objective transportation management strategies to improve long-term performance of urban mobility and transport systems, through a wide range of measures, including adaptive traffic management systems that ad-just in real-time to disruptions, predictive analytics to preemptively address potential system stressors and innovative, energy-efficient solutions like dynamic routing and adaptive lighting, (e) employ participative methods to engage citizens through a co-creation process via Living labs in three demonstration cities (Larisa, Odessa, and Bratislav