RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'What does your blood remember? The memory of hematopoietic stem cells.'.

assistant: **Concept**

Human organism produces over a million new blood cells each second. The hematopoietic system dynamically reacts to environmental stress and forms adaptive immunity to memorize and effectively fight the encounter pathogens. However, based on our recent studies and preliminary results, we propose that the adaptive capabilities and memory of the hematopoietic system reach far beyond the classical adaptive antigen-specific immunity. We hypothesize that hematopoietic stress induces clonal expansion of lineage-biased hematopoietic stem cells (HSCs) with epigenetic memory that faster and more effectively respond to secondary stimulation with a given stress factor. We propose that lineage-biased HSCs accumulating during aging provide a broad adaptive memory of the hematopoietic system, that is not restricted to immune cells, but includes all blood cell lineages.The aim of our proposal is to understand how the HSC-stored memory is created, maintained and recalled, and to clarify the underlying mechanisms. First, we will selectively stimulate granulopoiesis, erythropoiesis and thrombopoiesis to define the specificity and physiological role of hematopoietic memory provided by HSCs, both in vitro and in vivo. Second, we will use single-cell level fate mapping and sequencing to investigate clonal and epigenetic mechanisms driving the HSCs-based memory in mice. Third, we will test if aging pool of human HSCs consists of lineage-biased HSCs that store memory of the previously encountered stimuli. The humanized mice models will determine the clonal expansion of human HSCs upon primary and secondary stimulation with stress factors.Altogether, the expected outcome of the project is to understand how and why hematopoietic system adjusts to the environmental challenges upon aging. The prop
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Next-Generation Thyristor pulse technology for testing of high power magnetic components in DC Smart Grids', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Driven by the soaring demand for hybrid and electric vehicles and the large investments in renewable energies, the soft magnetic materials market is expected to reach the €100 billion mark by 2026. Together with increasing number of stringent regulations (particularly in the EU), this growth is expected to drive the emergence of advanced material testing equipment for the automotive and semiconductor industries. Accurate soft magnetic component testing is therefore becoming essential to select and develop efficient materials for key grid components and thus limit power loss and maximize system efficiency. However, there is still a clear lack of accurate measuring systems to test nonlinear high power magnetic components in DC voltage grids. This leads to a pressing market demand for innovative advanced quality testing solutions for these materials.Bs&T’s innovative prototype, PulseTester, has been designed specifically to fill this technical gap. Using the latest thyristor semiconductor technology and implementing an innovative circuit measuring system, we have been able to establish a revolutionary and effective pulsed technique capable of characterizing inductive component for middle voltage soft magnetic components. We can measure energy loss of magnetic components with unparalleled accuracy, offering a unique advantage in comparison with current alternatives, for a much lower price.With the final validation and full commercial release of PulseTester, we will help improve energy efficiency by facilitating adoption of highly optimized soft magnetic components in DC Smart Grids and renewable energy systems. We will gain a strategic advantage in the market, selling a cumulated 3,000 units by 2024 and raise our turnover by over €23 million. PulseTester will provide us inc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Optical imaging platform for high-throughput longitudinal studies of the eye in disease models' (OPTIMEYEZ).

assistant: **Concept**

Loss of vision is frequently related to disorders of the retina that may be either primary or secondary such as involvement in metabolic or neurologic disorders. Since the retina constitutes an easily accessible outpost of the brain, it emerged as top research target for non-invasive diagnostics of neurological diseases such as Alzheimer’s disease. Preclinical testing in rodents is an essential element in the process of exploring novel therapeutic compounds. The gold standard for such research and development read-out relies on histological confirmation, which, however, requires the animals to be sacrificed. In contrast, optical imaging methods enable rapid identification of pathologic tissue structures based on intrinsic contrast. In ERC Starting Grant OPTIMALZ, we have developed a novel multi-contrast optical imaging platform for longitudinal studies of the retina. Based on high-speed optical coherence tomography (OCT) technology, our prototype provides 3D images based on the light backscattered from the retina as well as polarization contrast for the identification of pigmented lesions, and OCT angiography for visualizing the microvasculature without the need for contrast-agent. Unlike histology, our platform allows for repeated, non-invasive imaging of live rodents’ eyes and thereby greatly reduces the number of animals required for a study. We have successfully demonstrated the powerful potential of our technology in rodent models of primary retinal degeneration and Alzheimer’s disease. The PoC project OPTIMEYEZ shall now expand our imaging portfolio to include additional models, improve technological aspects, and make our imaging platform accessible to key players in pharmaceutical industry. By securing intellectual property, developing business strategies, and es
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Novel PHAge MEthods for improved virus inactivation' (NoPHAME) targeting Horizon 2020.

assistant: **Abstract**

Provision of safe water is vital to ensure the stability and function of society and overall public health. The WHO estimates that 2 billion people still drink contaminated water, and lack access to safe sanitation. While the burden of waterborne diseases is disproportionally higher in poorer countries, the safety of our water supply is challenged everywhere by rapid world population growth and climate change, testing the capacity of sewage treatment systems and resulting in increasing environmental pollution. Therefore, effective removal and inactivation of viral pathogens during wastewater treatment is a global issue. Diseases due to consuming contaminated water are preventable and the resulting deaths can be avoided. Safe reuse of wastewater requires efficient inactivation of mammalian pathogens in the treatment process, especially emerging pathogenic viruses however current methods are established for bacteria and protozoa; far less is done for viruses due to greater diversity and the challenges of growing human and animal viruses. Bacteriophages, viruses of bacteria, offer an alternative as surrogates for mammalian viruses. In this fellowship, I propose to develop better systems to monitor and assess virus inactivation methods during wastewater treatment, through two specific objectives: (1) Identification of ubiquitous endogenous phage as surrogates for human/animal pathogenic viruses in virus inactivation evaluation; and (2) Develop phage activity assays to measure and evaluate the virus inactivation efficacy of novel wastewater reuse treatment schemes. Through this fellowship, I will gain multi-disciplinary knowledge and enhance my skills in virology, bioinformatics, microbiology and water technology. These acquired competences and experience will broaden my ski
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Investigating Neutrinos in Cosmology and Astrophysics' (INCA) under Seventh Framework.

assistant: **Objectives**

We propose to explore the role of neutrinos in cosmology and astrophysics via theoretical investigations and the development of numerical and computational tools. In the first case, we shall investigate further the phenomenology related to the cosmological neutrino mass and energy density determination, exploiting the forthcoming data from the Planck ESA satellite and other cosmological surveys and probes.  Particular attention will be devoted to the cosmological impact of new physics in the neutrino sector. In the second case, we shall consider the high and ultra-high energy sector of relevance for Cherenkov detectors (like the ongoing effort towards a Mediterranean km3 telescope) and Ground Arrays like the Pierre Auger Observatory.  An interdisciplinary and multi-messenger approach will be the common denominator in both cases: in the former field, we shall consider the implications from (and the consequences for) laboratory experiments like Katrin or neutrinoless double beta decay searches, as well as hints of new physics that could come from the first results of the Large Hadron Collider (LHC).  In the latter sector, we will link the predictions for the neutrino-related observables at high energy with cosmic ray and gamma-ray data (from instruments like Auger, HESS, MAGIC and GLAST).  Incursions in the intermediate energy ranges (MeV) are possible, especially related to the phenomenology of solar and core-collapse supernova neutrinos, and to the development of European plans towards a large underground facility for neutrino-related studies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Inclusive Science and European Democracies' under Horizon 2020.

assistant: **Concept**

The objective of ISEED is to identify, through an analysis of a variety of types of, and experiments in, public engagement on science-related questions and activities, generalizable characteristics and conditions that cultivate active and productive citizen participation in public deliberation. The aim is to construct a novel concept of ‘deliberative participation’ designed to enhance both the quality and the legitimacy of political decision-making, by focusing on the importance of knowledge-based deliberation. ISEED will build on and extend existing experience in the field of citizen science to explore the conditions under which participative and deliberative practices can be successfully implemented for the purpose of building forms of knowledge-based democratic governance complementary to political representation in democratic societies. ISEED combines theoretical analysis, empirical research, and small-scale experiments. It will reassess the role of the public sphere to include a novel notion of deliberative participation in a plurality of publics and counter publics. It will empirically explore how current practices of citizen participation in science can offer innovative methods to confront and overcome a number of current obstacles faced by democratic participation and decision making. It will develop a new tool to describe styles of argumentation in traditional and digital media and analyze the role of emotion and reason in polarised debates on contemporary scientific issues. The ISEED consortium, committed to multi and inter-disciplinary research, aims to deliver scalable results to foster deliberative democratic processes in Europe and other knowledge societies.


**Keywords:** Citizen participation in research,  Citizen science and knowledge society,  Polariz
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Development of a long term strategy based on genetic resistance and agroecological approaches against coffee wilt disease in africa.' to be submitted under Fifth Framework.

assistant: **Abstract**

Coffee Wilt Disease (CWD) caused by Fusarium xylarioides Stey. mainly affects Robusta Coffee (Coffea canephora Pierre) from DRC to Uganda and Tanzania. It is currently the major biotic constraint of Robust growing in these countries, as it used to be in Central and West Africa in the 1950's. and unlike many other coffee diseases can cause rapid death of the trees. For many years it was regarded as a minor disease following major programmes of replanting with tolerant varieties and comprehensive sanitation measures. It would appear that varieties previously considered resistant to the disease now appear to be susceptible. In that context, and taking into account the subsistence systems prevailing in Africa, durable genetic resistance is the most suitable control method. The general objective of the project is thus to develop a strategy for durable resistance in agrosystems prevailing in Africa. The project aims at securing a better knowledge of the disease and of the host/pathogen interactions, both in the field and under laboratory conditions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Airborne Wind Energy TRAining for Industrialization Network' in the context of a Horizon Europe call.

assistant: **Objectives**

The objective of AWETRAIN is to train 12 ESRs on how Airborne Wind Energy (AWE) can be integrated into the industrial energy system. Disruptive innovation like this, is needed to fulfill the goals of the Green Deal, Fit for 55, the revised RES Directive and the Offshore Energy Strategy. AWE can access wind resources conventional cannot, thus, can help fill gaps in renewable energy generation. Furthermore, it has the potential to cut the capital cost of wind energy by half, while doubling the production capacity.The research program is based around 10 attractive multi-disciplinary ESR projects, distributed across Universities and technology start-ups. The first scientific workpackage looks at improving the reliability of the devices so that it is viable for industrial exploitation. The second scientific workpackage will contain ground-breaking research, looking at how the technology can be scaled up to construct grid-scale power plants. The final ground-breaking scientific workpackage, looks at the potential impact of this technology on European electricity grids and the transformations needed in society and the AWE sector to acheive these benefits.The intersectoral training will develop the skills needed in the energy industry to facilitate the green transition. Increasingly professionals need to work in multi-disciplinary teams, have the awareness of how their sector is evolving and the agility so their work can be adapted for maximum impact. The skills developed in this network can be transferable to industrializing any emerging technology. This will give the ESRs highly attractive skills, for transforming ideas into products, that will boost their career prospects. This will be done through networking among their scientific peers and engaging with the general public.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Future Regional Aircraft Requirements Survey - Part 2' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The objective of FRARS-2 (Future Regional Aircraft Requirements Survey – Part 2) is to conduct a survey of airlines’ high-level requirements for future regional aircraft, with specific focus on North American and African operators. This new survey is the continuation of a study conducted under the first Clean Sky Call for Proposals (Future Green Regional Aircraft requirements).In addition to an extended geographical coverage, the present study will bring innovative multi-criteria decision-making support methodologies and tools in order to translate the opinions expressed by the airlines' executives into concrete technology options for the Clean Sky GRA ITD.The proposed consortium (ENVISA & SustainAvia) has a long-time expertise in the fields of airline surveys and multi-criteria / interdependence models. Both companies have successfully cooperated on a joint survey of worldwide air operators and regulators under Clean Sky SGO ITD's CARING project. Furthermore, the consortium has multiple contacts with high executives of operators in both regions of interest for the present study - North America and Africa.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'IPv6 Wireless Internet Initiative' in the context of a Fifth Framework call.

assistant: **Objectives**

The 6WINIT project will validate the introduction of the NEW MOBILE WIRELES INTERNET in Europe - based on a combination of new Internet Protocol version 6 (IPv6) and wireless protocols (GPRS and UMTS/3GPP). This offering will solve current problems of the scarcity in the IP and wireless world of the following: IP addresses, quality of service and security from the IP side and lack of spectrum and bandwidth from the wireless side.The project will set up and validate one of the first operational IPv6-3G Mobile Internet initiatives, with customers having native IPv6 access points and native IPv6 services in a 3G environment. The project will concentrate on mobile and wireless aspects of the system. It will link into existing IPv6 wired infrastructures, using mainly existing applications for the validation, with emphasis on the clinical and M-Commerce domains. In most cases the applications themselves will not be developed inside the project. Objectives:The principal objectives of the 6WINIT project are the following:To validate the introduction of the NEW MOBILE WIRELESS INTERNET in Europe- based on a combination of the new Internet Protocol version 6 (IPv6) and the new wireless protocols (GPRS and UMTS/3GPP);Tovalidate the integration of the protocol suites in (1) into real applications by running complete application testbeds;To ensure that the implementations of (1) are generic, and not specific to a particular supplier or operator;To ensure that the validation applications of (2) are not too tied to specific choice of applications;To ensure that the international perspective is maintained.We aim choose as applications some generic, but important ones. In addition we wish to consider a specific domain in depth for some applications testbeds, and have settled on the clin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Predicting carbon release from forest soils through priming effects: a new approach to reconcile results across multiple scales' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Feedbacks between plants and soil under environmental change are likely to have a significant impact on ecosystem carbon cycling. Recent work has shown that increased atmospheric carbon dioxide concentrations have enhanced tree growth in forests. However these increases in growth can also cause ‘priming effects’ whereby microbial degradation of soil organic matter is stimulated by fresh carbon inputs, such as plant litter, releasing additional carbon from the soil. Given that forest soils represent the largest terrestrial carbon pool, priming effects could cause a major release of carbon dioxide to the atmosphere. Despite their potential importance in ecosystem carbon dynamics under environmental change, the processes and mechanisms underlying priming effects are still poorly understood. This is in part due to the enormous disparities in the experimental scales and methods required to study microbial processes vs. ecosystem carbon dynamics and the difficulties in extrapolating the results of laboratory studies to the ecosystem level. This project will significantly advance our understanding of the role of priming effects in forest carbon dynamics in different forest types and reconcile the experimental problems of scale using multidisciplinary nested studies across multiple scales. The nested design will explicitly test the validity of extrapolations made at one scale to predict effects at another.  The ultimate aim is to allow the extrapolation of results from small-scale studies of priming to the ecosystem level for a wide range of forests. The results will establish this fundamentally new approach as a widely applicable method in the study of plant-soil feedbacks. This research will provide the first comprehensive comparative dataset on priming effects across forests