RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Numerically exact theory of transport in strongly correlated systems at low temperature and under magnetic fields'.

assistant: **Objectives**

Transport in strongly correlated materials is one of the central topics in condensed matter physics. Due to major prospects for technological applications, particular attention is paid to the cuprate superconductors, and by association, to kappa-organic materials and moiré systems. The last decade has seen great progress in the understanding of the generic high-temperature properties of these systems, largely based on the microscopic yet simplified interacting lattice models. However, there are multiple outstanding questions regarding their low-temperature physics.The mechanism of the strange-metallic linear-in-temperature resistivity and its relation to superconductivity have so far eluded understanding. There is conflicting evidence for the quantum critical (QC) scenario, which is a common view that there is a zero-temperature QC point hidden behind the superconducting dome on the phase diagram of the cuprates. Recent magnetoresistance measurements in these and other materials contribute to a puzzling phenomenology. The factors that determine the magnitude of the superconducting critical temperature are also poorly understood. Further progress is blocked by the limitations of quantum many-body numerical methods.To address these questions, we propose to employ a highly promising new approach to the numerical solution of the many-electron problem. It may overcome the long-standing limitations and allow for an unprecedented accuracy and control. The real-frequency diagrammatic Monte Carlo method will yield numerically exact results for the resistivity in a range of lattice models, at low temperature, and as a function of magnetic field. These results will help interpret recent experimental results, set new predictions, and open doors to reverse-engineering of functional
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'EUROVILLAGE ON THE EUROPEAN INFORMATION INFRASTRUCTURE' (EVENET) targeting Fourth Framework.

assistant: **Abstract**

The aim of EVENET is to develop and validate a European telematics system bringing a wide range of tourist services onto the Internet using World Wide Web technology. Telematics catalogues, price lists, information files, maps, pictures and on-line reservation will be among the facilities accessed. The most novel feature of EVENET is its potential for world-wide transmission of a rich variety of tourist information coupled with the possibility of on-line bookings. The two-year project will culminate in pilot implementation and validation during a complete tourist season with a particular group of tourist operators. Its subsequent extension to other tourist operators and the general public is also envisaged.The aim of the EVENET project is to develop and validate an innovative information system based on the World-Wide Web technology in the social tourism activity sector. This system will bring to a world-wide network (Internet) the Eurovillage telematics catalogues, price lists, information files, promotions, maps, pictures and on-line reservation.The project is limited initially to Eurovillage European partners (company members, operators, ...) and will give the opportunity to verify and demonstrate the potential of telematics applications for tourism across Europe. Depending on the results of the test experiment during a whole tourist season, the system should be extended to more users : new professional operators and then general public.The most innovating characteristic of the EVENET project is the possibility in a real-life environment of diffusing extremely rich multimedia information throughout the world, of providing interactive and navigational access to these information and of allowing on-line bookings.The project will be split into four phases (market study,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Development of a complex extracorporeal technology for the treatment of multi-organ-failure'.

assistant: **Innovation**

- Development of microspheres for the removal of endotoxins, cytokines TNFalpha and IL-1beta, exotoxin SEB, bilirubin and toxins of liver failure- Development of biodegradable endotoxin binding microspheres as a tool of higher safety of MDS.- Development of MDS-device including the optimization of the plasma filter and the establishment of an intelligent software and hardware to accomplish high safety standards and facilitated handling- In vivo testing and clinical testing of MDS in specific animal models (endotoxin shock and liver failure) and patients suffering from MOF, respectivelyMulti organ failure (MOF), very common in septic shock patients of any age, is a multifactorial disease involving nearly all organs and systems of the human being. Its average mortality is in a range of 40-50%, and prognosis has not significantly improved during the last 10 years. The course of MOF is characterized by complex structure, initiated by endotoxins, followed by a cascade-like activation of different cells and systems. The main objective of this proposal is to establish a therapeutically system which is able to influence the multi-factorial pathophysiology at 3 different levels. The first level concentrates on the removal of free soluble endotoxins and exotoxins from blood. The second level is concerned with the removal of the principal cytokines, TNF-a and IL-1 +, by specific adsorbents. Finally, the third level includes the therapy of acute liver failure, including hepato-renal syndrome. This three step concept is based on a very recently introduced blood purification technology: the WMicrospheres based Detoxification System(MDS). MDS is a newly developed adsorptive technology, based on a simultaneous adsorption/filtration technique, which employs microspheres in the size of 2
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Chemical evaluation of drinking water disinfection byproducts' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Disinfection byproducts (DBPs) are generated when disinfectants such as chlorine, ozone, chloramine, or chlorine dioxide, react with natural organic matter and/or bromide/iodide present in source waters, and they may pose health risks. Despite intense research carried out in this field, more than 50% of the total organic halogens formed during water disinfection still remain unidentified. Additionally, iodinated DBPs have been found not only in naturally iodide containing waters disinfected, but also in treated source waters where iodide concentration was very low. Thus, other potential sources of iodine, such as iodinated X-ray contrast media used for medical imaging are being explored.The estimated toxicological potency of individual or defined mixtures of DBPs does not account for the magnitude of effects reported in the positive epidemiologic studies, suggesting the need for toxicological evaluation of whole DBP mixtures, including the unidentified DBPs. This problem was addressed by a multi-disciplinary team of researchers from the U.S. EPA in a project known as the “Four Lab Study”, in which toxicological effects of complex DBPs mixtures generated under drinking water chlorination and ozonation/postchlorination scenarios were evaluated.Chloramination of water has been observed to increase the formation of highly cytotoxic and genotoxic iodinated DBPs, nitrosodimethylamine and other nitrosamines; to release solubilised lead in drinking water distribution systems, and to produce skin rashes, respiratory effects, and digestive effects in the population.In this context, the proposal ChE-WADISBYPRO aims to produce and chemically characterize water concentrates of chloramine-derived DBPs mixtures that are suitable to be used in toxicity studies to evaluate the environme
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Representations of finite groups of Lie type and associated algebras'.

assistant: **Objectives**

The proposed research is in the representation theory of finite groups and algebras and consists of two parts: one focusing on the finite groups of Lie type and their associated algebras, the other part involving the study of Steenrod algebras with the help of A-infinity algebras. In the context of finite groups of Lie type, we propose to show Cabanes-Rickard and apos;s conjecture on Alvis-Curtisduality, beginning with some specific cases. My thesis contains the original construction of a complex H of Hecke algebras of type A, which was shown to induce a derived equivalence; for general linear groups H is linked to the complex inducing the Âlvis-Curtis duality. One research goal is to show that H induces a homotopy equivalence.But more importantly, one can construct a graded algebra S with the aid of H and relate it via the index representation of the Hecke algebra to the q-Schur algebra. Thus S is a new algebra related to a well-known algebra, making it a most interesting new object. The programme will be hosted b y Dr. Karin Erdmann at the Mathematical Institute, University of Oxford, who is an expert on algebras of this type. Finally, we would study the structure of the group cohomology over the Steenrod algebra and define that structure in a purely algebraic way in terms of the group algebra, with aid of A-infinity algebras. In addition to fostering the development of a young researcher, this programme would reinforce research ties between France and England.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Bioactive reinforcing bioink for hybrid bioprinting of implantable bone'.

assistant: **Concept**

3D bioprinting is an emerging technique that offers promise for fabricating implantable tissues. Despite significant advancements, the field struggles to replicate the mechanical robustness and biological complexity of native tissues, particularly in applications requiring high mechanical strength such as bone. This proposal introduces 'BioForceInk,' a bioactive reinforcing bioink designed for direct bioprinting alongside a cell-laden hydrogel within a cell-conductive environment. The microparticle-based bioink is printable at room temperature and solidifies at 37°C, forming a stiff, porous scaffold within the construct. Our preliminary studies demonstrated its excellent printability, mechanical properties, and osteoconductive capabilities in a hybrid bioprinting context. To enhance vascularized bone differentiation in vitro and support bioprinted implant integration and bone recovery in vivo, the bioink will be enriched with osteogenic and vasculogenic factors.Throughout this project, we aim to develop the growth factor-loaded BioForceInk and utilize it for creating vascularized bone implants by hybrid bioprinting in tandem with cell-laden soft bioink. We will then evaluate the regenerative potential of the bioprinted vascularized bone implants in a critical-size bone loss model. Additionally, we plan to test the technology with industrial partners and prepare it for commercialization by the end of the project. BioForceInk offers a unique combination of mechanical support and biological activity that facilitates the single-step fabrication of physiologically relevant bone implants. This innovation has the potential to significantly narrow the gap between bioprinting technology and clinical application, contributing to the development of personalized, mechanically robus
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'SRF target genes in epilepsy' in the context of a Seventh Framework call.

assistant: **Objectives**

The aim of this project is to identify genes regulated by SRF (Serum Response Factor) in the epilepsy. Epilepsy is a chronic neurological disorder, affecting 1-3% of human population with temporal lobe epilepsy (TLE) being the most common type in adults. Unfortunately, current anti-epileptic drugs are ineffective in more than 70% of TLE patients. Therefore, it is very important to understand the molecular mechanism underlying the pathology. Multiple pieces of evidence imply that aberrant synaptic plasticity may underlay epilepsy. Inactivation of SRF was shown to cause deficiency in hippocampal synaptic plasticity and learning. In addition, impaired axonal outgrowth, guidance and synaptic targeting has been reported. SRF was also suggested to be crucially involved in neurological disorders like epilepsy. The proposed project is based on the hypothesis that regulation of gene transcription by SRF, will play a crucial role in the aberrant plasticity observed in epilepsy. To confirm this hypothesis we will (i) identify new target genes regulated by SRF in the animal model of aberrant neuronal plasticity by microarray studies, (ii) confirm results obtained by global gene expression analysis using methods Q-RT-PCR, CHIP assay, in situ hybrydization and immunohistochemistry, (iii) further characterize the function of SRF-dependent effector proteins in synaptic plasticity (dendritic spines formation / neurite outgrowth). Our data will have an impact on the current understanding of the pathogenesis of epilepsy, as well as influence the development of new therapeutic opportunities by selectively targeting aberrant plasticity-related SRF effectors. Moreover, the results obtained by global analysis may become an excellent starting point of many new basic research avenues. We will u
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Innovative fatigue and damage tolerance methods for the application of new structural concepts' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

In order to allow the industry to use newly developed manufacturing methods, which all promise high efficiency but lack a good damage tolerance capability under certain circumstances, the proposed project aims to develop new damage tolerance assessment tools for the new and high performance manufacturing techniques: High Speed Cutting (HSC), Laser Beam Welding (LBW) and Friction Stir Welding (FSW), all three leading to a type of structure which is close to an ntergral structural design. This design offers benefits, e.g. from the cost point of view, but also some concerns from the damage tolerance capacity point of view. Since the damage tolerance behavior of structures s a crucial point in the application of the new techniques, it limits today it's application. Therefore, the DaToN project provides an important step forward for strengthening competitiveness of the European aeronautic industry by contributing to the aircraft development and operating costs reduction via the development of advanced and high damage tolerance performance structural concepts using bothnew automated fast manufacturing processes and new metallic materials for optimizing the inducedstructural weight reduction.The present proposal aims to provide missing fundamental knowledge and assessment tools for the damage tolerance of integrally stiffened structures, which are produced by means of the three new production methods: LBW, FSW and HSC.The project does not aim to develop the manufacturing techniques. The main scientific and technological objectives of the project are : o To develop and validate calculation tools for the assessment and the understanding of the damage tolerance behaviour of integrally stiffened structures using high performance manufacturing processes : High Speed Cutting. Laser
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Cell and molecular basis of cortical development (CONSORTIUM ON CORTICAL DEVELOPMENT)'.

assistant: **Concept**

A better understanding of the mechanisms that control the development of the cerebral cortex is requisite to the prevention and treatment of many neurological and mental disorders such as brain malformations, learning disabilities and behavioural disorders. This research is thus directly relevant to issues of public health and quality of life in the EU. This consortium brings together several laboratories with complementary expertises in molecular and cellular techniques and will use this multidisciplinary approach to address the key questions of the generation of cortical neurons, of radial and tangential neuronal migration, the formation of cortical layers, the differentiation of the various cortical areas and the formation of connections. The research program is divided into well-defined operational work packages, allowing easy monitoring of progress. The results and reagents will be shared among participants, reported in international meetings and journals, and patent covered when applicable.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'SAFEAIR Advanced Design Tools for Aircraft Systems and Airborne Software' under Fifth Framework.

assistant: **Concept**

SafeAir will contribute to the overall goal of facilitating aircraft subsystem and component development in order to foster the competitiveness of the European avionics industry. Its focus is on substantially improving the electronic system development process, leading to a 35-40% reduction in development cost for airborne software systems. This will give European Avionics Industry process leadership in systems- and software development. Beyond this, the exploitation potential addresses a wide range of European industries with similar challenges.SafeAir will develop a model-based methodology for designing dependable embedded systems. The approach will be based on the integration of mature, well-accepted notations and tools integrated in a usable development environment. The result will ensure a high degree of dependability of avionics systems in spite of ever increasing complexity. Salient novel features are rigorous verification of critical properties, automated, certified code generation and automatic validation of the code with respect to the design.Objectives:SafeAir aims at the development of an Avionics Systems Development Environment (ASDE), encompassing technologies, methods and tools that meet the high dependability needs in the area of embedded control systems. Challenges in designing and developing such systems for avionics and other industrial application of similar complexity span the whole development cycle. Requirements need to be described unambiguously and correctly, the design, code and implementation must be checked for correctness and reliability with respect to the requirements. At the same time, the development effort must be kept low to meet the tight time to market. SafeAir's goal is to substantially improve the electronic and embedded systems de
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'The development of an automated system for the cutting and plantingof rose cuttings'.

assistant: **Objectives**

The propagation of roses by cuttings is one of the most applied (propagation) methods. At present the cutting and planting of potroses is a manual process/procedure. The major (technical) limitations are the low productivity and the variations in quality. Moreover, it is a boring job. Therefore, the objective of the intended R&D-project is to develop an autornated s,vstem for the cutting and planting of rose cuttings which has the following specifications: 1) a high productivity (> 7200 cuttings/h), 2) a high and uniform quality, and 3) a short through-put time (reduction of the chance of infection). The proposed system will be composed of a number of innovative techniques, such as a recognition (vision) system, a robotic systern and a handling clip system. Preliminary estimates show that the potential benefits (industrial impact) of such a system are favourable compared to the (development) costs. A prototype will be built which will provided the data for the design of a commercial autornated system for the cutting and planting of rose cuttings. The consortium consists of developers and endusers of the proposed system.