RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Dft study of metal particles on support oxides' (1994-1998).

assistant: **Concept**

The project is based on the use of quantum chemical methods for the investigation of catalysts made by metal particles supported on oxides. This study is interesting not only for heterogeneous catalysis, it concerns also problems connected to adhesion between metals and oxides, which is of relevant interest in microelectronics or in metal coatings. New developments of Density Functional Theory tools will be tested and used to obtain a better description of the phenomena occurring at metal/oxide interface.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Predictive maintenance platform for industrial assets based on AI and IoT' (2014-2020) under Horizon 2020.

assistant: **Objectives**

In a world where everything is run by machines, securing their optimum performance is paramount. When a machine begins to fail or stop unforeseen: production is compromised, maintenance costs are triggered and performance and quality go down. Sigma Industrial Precision is a Spanish ICT-SME specialized in the development of predictive maintenance based on electrical analysis focused in the development and commercialization of predictive-sigma, a predictive maintenance platform for industrial assets. We believe that electrical data can provide critical information. With this premise in mind we have recently developed and demonstrated a disruptive, smart solution towards Factory 4.0, a cost-effective and easy to use. Thanks to advances in IoT architectures and data analytics, Predictive Maintenance (PdM) is one of the most prominent and fastest growing use cases of IoT technology in industrial settings today and empowered by artificial intelligence that can help to decrease downtime and improve asset performance drastically. We are offering a complete solution, predictive-sigma, including electrical sensors and access to predictions about potential asset failures. With our solution we can guarantee: less stoppages and more production, only the necessary maintenance and ensure quality and efficiency. Sigma is cemented on an experienced team composed of engineers and scientist with skills in business and technology development. In 2018, our company was selected as one of the 50 startups with more projection of Catalonia (Spain) according to the Investment Forum 2018 (Barcelona & Catalonia Startup Hub).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Enhancing the implementation security of quantum key distribution'.

assistant: **Innovation**

The advent of quantum computers poses a severe threat to the security of our existing communication infrastructure. Quantum Key Distribution (QKD), which bases its security on the laws of physics rather than unproven computational assumptions, has been proposed as the ultimate solution to protect the long-term security of our communications. However, due to inevitable imperfections in the devices used to implement QKD protocols—particularly the sources—practical QKD systems suffer from security vulnerabilities that could be exploited by attackers to gain unauthorized information, thus invalidating QKD's seemingly ironclad security guarantees.Recently, the scientific community has started to address this critical issue, with initiatives aimed at both developing security proofs resistant against device imperfections, and at experimentally quantifying their magnitude. However, these security proofs have tended to consider imperfections in isolation, and are thus unsuitable for real-world implementations suffering from multiple imperfections simultaneously. Moreover, the existing experimental works have not focused on quantifying the specific parameters required to apply these security proofs, limiting their practical utility.In this project, we aim to significantly enhance the implementation security of QKD through two primary objectives. The first is the development of a rigorous and robust security proof that, by integrating previous approaches, incorporates all possible device imperfections, and could thus secure practical implementations against all attacks aiming to exploit them. The second objective is the development of source characterization tests that can measure the specific parameters needed to apply this security proof, demonstrating its ability to secure real
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Microbial Electrochemical Cells with modified electrode based on ‘forest’ like carbon nanotube (CNTs) and CNT- conducting polymers nanocomposites' (CNTs), addressing dissemination and exploitation.

assistant: **Impact**

Microbial electrochemical cells (MECs) show promises for energy recovery from waste and efficient wastewater treatment. MECs are bioelectrochemical reactors in which chemical energy stored in reduced substrates is converted directly into electrical energy (or hydrogen) through immobilized microbial catalysts, usually termed electroactive biofilms (EAB). Current MEC performances are not optimal and prevent their use in large-scale applications. Slow electron transfer at the microorganisms/electrode interface and low overall electroactivity of EABs are among the key scientific bottlenecks that need to be resolved in order to increase MEC output and enable their cost-effective implementation in wastewater treatment plants (WWTP). A possible solution is the development of biocompatible advanced materials for electrodes that will enable efficient “wiring” of EAB to the electrode. This project focus on development of such electrode materials and their implementation in established MECs.The candidate will use ‘forest’ like carbon nanotube (CNTs) and CNT- conducting polymers nanocomposites (CNT-NCs) to modify conventional electrodes for MECs. The new electrodes will have high surface and biocompatibility and support a fully active EAB, thereby increasing extracellular electron transfer and power (or hydrogen) output in MECs.The training facilities and expertise of the host organization will be used to fulfill the multidisciplinary training of researcher needs for development of an independent research career.  Additional training budget management and technology transfer provided within this project will add to the core skills of the candidate and enable her to take forward Research and Technology Development programmes.Moreover, the results could be of enormous global environm
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Mix-in Organic-InOrganic Redox Events for High Energy Batteries'.

assistant: **Innovation**

The ever-increasing demand for improved electrochemical energy storage technologies has fostered intense, worldwide and interdisciplinary research over the past decade. The field of positive electrode materials remains largely dominated by transition metal compounds in which only the redox of metal cations contributes to the energy storage. The development of new materials and technologies, wherein both anions and cations display reversible, multi-electron redox, is bound to strongly impact this field. MOOiRÉ will challenge this goal through innovative approaches on Metal Organic Compounds and Frameworks (MOC/Fs) with mix-in many-electron reversible redox of both, transition metal cations and organic ligand anions. Building on our preliminary results MOOiRÉ will adopt an integrated approach. We will combine performance oriented MOC/F molecular design supported by in-operando analytical inspection tools with novel electrode engineering approaches to overcome the limitations and enable efficient electrochemical charge storage. Through this highly interdisciplinary research, MOOiRÉ intends to advance the science and technology of mix-in redox MOC/Fs for next generation batteries, supercapacitors and their hybrids. MOOiRÉ will also be a major systematic study of the fundamentals of MOC/F-based energy storage systems in view of a practical implementation. The overall impact will extend beyond the energy science community: the developed knowledge, tools and procedures will influence research and development related to porous composite materials, sorption, ion exchange and electrocatalysis. In the context of energy storage, this will be a disruptive development, enabling the use of MOC/Fs electrodes, with superior levels of performance as compared to current technology, at aff
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The anoikis suppressor TrKB as a target for novel anti-cancer agents' (TRKCANCER), addressing dissemination and exploitation.

assistant: **Impact**

The failure of anti-cancer therapies generally results from locally intractable invasive growth or from the presence of metastases refractory to treatment with curative intent. A novel therapeutic strategy is to develop new anti-cancer drugs specifically targeting the invasive or metastatic phenotype of tumour cells. We propose to validate at the preclinical level a strategy that targets the critical mechanism allowing apoptosis evasion and survival of invasive or metastatic tumour cells. Anoikis is a process by which a cell detached from its resident tissue undergoes apoptosis as a result of loss of normal cell-matrix interactions. Loss of anoikis allows survival of cancer cells in abnormal microenvironments, such as tissue compartments invaded by the primary tumour, and the intravascular compartment during the metastatic process. Participant 2 has recently discovered that the BDNF receptor TrkB is a potent suppressor of anoikis and is responsible for apoptosis evasion that occurs in aggressive human tumours overexpressing TrkB (Douma et al., 2004). The aim of the present proposal is to validate TrkB as a target for new anticancer drugs, aiming to restore anoikis and thereby destroy the invasive and metastatic cancer cells. This validation will include the identification TrkB-expressing tumour cell lines amongst a collection of resected human cancers. Then, abrogation of TrkB mediated signalling will be achieved by either selective TrkB mRNA-targeting small interfering RNAs (RNAi) delivered by viral vectors, or by novel and potent small molecule inhibitors that will be designed and synthesized. The efficacy of these tools will be assessed by using anoikis-sensitive cell models and xenograft mouse models, particularly orthotopic metastasis models derived from human tumo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'New approaches for understanding oceanic carbon uptake' (2007-2013).

assistant: **Innovation**

The oceans play a crucial role in the uptake of atmospheric carbon dioxide (CO2), a man-made greenhouse gas that strongly influences global climate. Certain marine organisms are hypothesized to greatly enhance CO2 removal during growth. A percentage of these cells subsequently sink, transporting the C to depth where it remains for millennia. Research has shown that one such group of organisms, di-nitrogen (N2) fixers or diazatrophs, are much more globally prevalent than previously thought and may even be further enhanced near zones of intense subsurface denitrification. As such, we propose to examine how the interactions between denitrification and N2 fixation contribute to particle export in one such area, the Gulf of California and adjacent waters of the eastern tropical North Pacific.  Measuring what controls the magnitude, timing, and depth of particle export in marine systems is difficult. Here, we will use the short-lived radioisotope pairs 234Th:238U and 210Po:210Pb to measure diazatroph mediated particle formation, export, and remineralization in samples to be collected during a funded cruise (U.S. NSF) in the N. Pacific in August 2008. Preliminary studies suggest that when used in tandem, these radionuclide pairs provide unique temporal and spatial insight into the mechanisms that modulate marine biotic and abiotic particle formation and sinking throughout the water column.  This proposal combines the expertise of two renowned radiochemists and will allow for an international exchange of cutting edge analytical techniques. Results will include much needed improvements in radiochemical export models that can be applied in a range of ecosystems. Understanding what controls particle formation and export in marine systems will provide insight into what may control
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Ti-Graphene Bone Tissue Template Engineering', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The BonE-GraphT aims to develop a new approach, based on bone template engineering using which the entire load-bearing structure might be possible to regenerate for replacing the damaged bone. The proposed approach, once developed, will be possible to align with the tissue-engineering bio-reactor technology for in-theatre use, which may be able to meet the demand for current shortage in treating the damaged load-bearing long bones (e.g. tibia femur) in trauma, osteoporotic bones and other bone defects. Within my research I am going to develop a new biomaterial: Calcium Phosphate coated graphene composite on porous Ti-alloy substrate via pulsed laser deposition techniques for enabling biocompatibility via osteoconductive process, promoted via progenitor stem cells. For research training as an orthopaedic materials engineer within which I aim to solve orthopaedic defects as a global problem I will deal with the following Research Training Activities (RTAs); i) Ti-alloy based graphene/calcium phosphate materials processing using femtosecond PLD; ii) Characterization of bio-active materials surface; iii) Characterization of cell cultivation, toxicity, attachment and mineralization; iv) Design of model bone structure.This training is not only beneficial for the my scientific career development, but also for the host institute (the University of Leeds) and the general public health. The above listed training activities will be supplemented by a number of non-Technical skills for my career development. As a result of this cross-disciplinary project the fellow will be a well-rounded biomaterials research engineer who will be in future qualified for perusing an academic career at the University of Leeds in the area of advanced biomaterials for tissue engineering and drug deliver
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'A unique and universal antibacterial coating for prevention of hospital acquired infections associated with the use of medical devices' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The aim of the current project is to develop a strong business plan that includes market analysis and clinical validation strategies to commercialise CytaCoat.  1 in 18 patients in a European hospital acquire Healthcare-Associated Infections (HAIs) mainly as a result of colonisation and formation of microbial biofilms on the surface of medical devices that are in lengthy contact with patients. At present, antimicrobial substances and silver agent coating are used as preventative measures, while antibiotics are used for treatment following HAIs. These strategies either contribute to antimicrobial resistance or potentially dangerous due to the release of harmful silver substances in the body.  To overcome this, CytaCoat has developed a unique and stable antimicrobial coating that uses non-toxic, biocompatible organic compounds that strongly bind to the surface of the device through covalent bonding. This impedes microbial colonization and reduces the likelihood of antimicrobial resistance to the coating. These features distinguish CytaCoat from all competing products on the market.  The first application for the coating are neonatal nasal prongs for non-invasive ventilation support, however the coating can be applied to all invasive and non-invasive medical devices. The research performed to date strongly supports CytaCoat’s ability to hinder microbial colonisation. The coating is easily applied to all devices using a defined protocol developed by the company. This project will help facilitate the road towards commercialisation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Five Challenges in Computational Anatomy' (FCCA) under Seventh Framework.

assistant: **Objectives**

New medical imaging technologies encode human anatomy in a wide variety of data structures. Computational Anatomy (CA) offers an approach to synthesize this plethora of data by comparison of anatomical features using smooth invertible transformations specific to the data structure.This proposal is for work to develop new mathematical and numerical methods for image analysis in the framework of CA, aimed at meeting the following five challenges in image analysis for the comparison and interpolation of shapes in biomedical images of the heart and the brain.1. Data structure: Develop a unified approach for registering images encoded in a wide variety of data structures. The unifying concept in our approach is the momentum map, a fundamental concept from the theory of Lie group transformations.2. Data fusion: After placing the transformations of the variety of data structures into the same conceptual framework using momentum maps, synthesise (fuse) their multiple modalities of information by accounting for the different transformation properties of the different data structures under smooth invertible maps.3. Multiple resolutions: Develop the momentum map framework to enable registration of data at multiple resolutions by concatenating the Lie group transformations that define the momentum maps.4. Time-varying (4D) images:  Treat time-varying images in this geometric framework by matching snapshots in time using geodesic splines that interpolate the image snapshot from one time to another. Quantity the effects of noise and uncertainty in 4D image analysis.5. Changes in image topology: Extend the transformative approach to allow changes in topology in passing between images by using the method of metamorphosis.Simply put, the five challenges are: to 1. register images of dif
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Returning to a Better Place: The (Re)assessment of the ‘Good Life’ in Times of Crisis' (Re), addressing dissemination and exploitation.

assistant: **Impact**

What makes for a valuable and good life is a question that many people in the contemporary world ask themselves, yet it is one that social science research has seldom addressed. Only recently have scholars started undertaking inductive comparative research on different notions of the ‘good life’, highlighting socio-cultural variations and calling for a better understanding of the different imaginaries, aspirations and values that guide people in their quest for better living conditions. Research is still lacking, however, on how people themselves evaluate, compare, and put into perspective different visions of good living and their socio-cultural anchorage. This project addresses such questions from an anthropological perspective, proposing an innovative study of how ideals of the good life are articulated, (re)assessed, and related to specific places and contexts as a result of the experience of crisis and migration. The case studies chosen to operationalize these lines of enquiry focus on the phenomenon of return migration, and consist in an analysis of the imaginaries and experience of return by Ecuadorian and Cuban men and women who migrated to Spain, are dissatisfied with their life there, and envisage/carry out the project of going back to their countries of origin (Ecuador and Cuba respectively). The project’s ambition is to bring together and contribute to three main scholarly areas of enquiry: 1) the study of morality, ethics and what counts as ‘good life’, 2) the study of the field of economic practice, its definition, value regimes, and ‘crises’, and 3) the study of migratory aspirations, projects, and trajectories. A multi-sited endeavour, the research is designed in three subprojects carried out in Spain (PhD student), Ecuador (Post-Doc), and Cuba (PI), in