RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Validation of Actionable Genomic ABerrations in a paediatric Oncology Network for Doctorate students', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Pre-clinical drug development for paediatric cancers is very complex, resource intensive and requiring multi-disciplinary expertise and innovative approaches. The VAGABOND ITN, consisting of 12 academic and 6 non-academic partners from 8 European countries, aims to create a multidisciplinary and multi-sectoral program to validate new therapeutic interventions in paediatric cancer. This network will be sustainable embedded in the ITCC (Innovative Treatments for Children with Cancer) Consortium. The VAGABOND ITN will focus on 15 cutting-edge research projects studying molecular, epigenetic and immunological targets. All projects will (partly) include target identification, in vitro and in vivo validation, compound testing and preparation for clinical implementation. This consortium will highly stimulate international education and multi-disciplinary exchange of expertise in the different steps of pre-clinical drug development. This setting provides an opportunity for a unique European training network in which early stage researchers are equipped with a broad knowledge in pre-clinical drug development. Through this network students will gain access to other leading academic research groups, specialized multi-sectoral companies and the most innovative techniques and insights in the complexity of translational medicine to prepare them for future challenges in their career pathway. In this collaboration we will increase the commune expertise on tumour types and technical expertise for target validation. This will improve the implementation of interventions across paediatric cancer and strongly reduce the timeline from bench to the bedside.


**Keywords:** Pre-clinical drug development, paediatric cancers, target-drug combinations, compound testing and clinical implementation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Development of novel analytical and experimental approaches for an in-depth characterization and optimization of Silicon Photomultipliers'.

assistant: **Objectives**

Sensors capable of detecting single photons are of critical importance for a very wide range of scientific and technical applications in such areas as medical imaging, biotechnology, high energy physics, scientific instrumentation, communication, and homeland security, including, in particular, positron emission tomography, flow cytometry,  Cherenkov cosmic ray telescopy, laser ranging, optical time domain reflectometry or beam loss monitoring in particle accelerators and light sources.Silicon Photomultipliers (SiPMs), in particular, are an emerging and very promising technology due to their photon number resolution at room temperature, insensitivity to magnetic fields, compactness and relatively low operating voltages. Furthermore, they are cheap to mass-produce, especially in comparison to conventional photomultiplier tubes. In order to evaluate their potential for a specific application, it is necessary to quantify their fundamental parameters as a particle detector, as well as in combination with scintillators or optical fibers used for signal generation and transport, in detail.In the frame of this Marie Curie IIF project, a comprehensive analytical probabilistic model of the SiPM response shall be developed that will take the specific excess noises of crosstalk and afterpulsing, nonlinearities and saturation effects into account. Based on this model, a full set of analysis, measurement and characterization methods will then be built up. This will allow for selecting an optimum SiPM design and model for a specific application as accelerator, nuclear or medical physics instrumentation and thus contribute to an overall improvement of the respective application. Finally, reliability and mass testing approaches and techniques, applicable for large-scale projects and fo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Dynamics and Structure of the Earth’s Mantle: a multidisciplinary approach' to be submitted under Seventh Framework.

assistant: **Abstract**

We propose a multidisciplinary approach involving mineral physics, geophysics and geodynamics to study the evolution and the current physical conditions of the Earth’s mantle. Starting from a mineral physics database, we will jointly invert long-period seismic waveforms and gravity data to infer 3-D thermal and compositional structure of the Earth’s mantle. The thermodynamic database used for the inversion will also provide the physical properties for time-dependent mantle convection computations. The reconstruction of the thermal and compositional evolution with most advanced computational techniques will validate the character of the T-C structures obtained from the observations. Moreover, these models will give insights on small-scale heterogeneities that are not resolved from the geophysical observations.  The proposed combined procedure has a greater potential for answering questions compared to conventional methods, which use only partial information. We expect to shed a light, for example, on the role and presence of water in the deep interiors, on the scale of mantle heterogeneities and on the presence of compositional stratification in the upper and deep mantle. All the specific results are included within the more general goal of achieving a better understanding of the Earth and planetary dynamics. As a consequence, external phenomena as climate change, volcanic eruptions, earthquakes and plate tectonics, that are intrinsically linked to interior dynamics, will be also better understood.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Scan2CAD: Learning to Digitize the Real World'.

assistant: **Objectives**

One of the most fundamental challenges in the digital age is to automatically create accurate, high-quality 3D representations of the world around us. This would have far-reaching impact, from enabling advances entertainment and immersive technologies (e.g., mixed reality) to medical applications and industrial manufacturing pipelines. Despite remarkable progress in scanning devices and 3D reconstruction algorithms, the resulting models remain highly impractical for display or use in virtual environments. This is due to the limited quality of these reconstructed 3D models, which is still far from the quality of assets designed by professional artists in countless of working hours. We believe that the key to addressing these shortcomings is understanding the design process of artist-created assets. We can then learn the correlation to real-world observations and replicate the process conditioned on these real-world input scans. In this proposal, we will answer the question ""How can we turn 3D scans into CAD-quality 3D assets?"".""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Active structures with smart materials: Modelling, control, numerical simulation and experimental validation', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

The project is dedicated to the active control for suppression of vibrations of flexible smart structures in the industrially active field of new materials and adaptive systems. Active structures are equipped with sensors, actuators and computer-based cont rol. New materials are used in the design of controllers and sensors yielding smart systems. The investigations consist in developing recent models, control laws, strategies for design optimisation, virtual simulation, and realization in hardware devices.The modelling covers coupling effects, structural defects and interface dynamics. The active control is considered in terms of the new H8 robust control theory. Choice and positioning of sensors and actuators is considered. Respective software is developed. The most important stage of the project is the experimental hardware validation. The technological issues of this project are combining of the most recent developments in sensor and actuator technology, networks, and signal processing and computer techniques to design new active smart systems.Active structures belong to the highly multidisciplinary and interdisciplinary mechatronics. Attractive virtues of the proposal are the new methodology for modelling; the novel on-line realization software; the new robust control strategies. An excellence of the project is the new technological solution realized in industrial equipment. Benefits for the researcher are entering new industrial problems in active structures reaching their independent statement and solving. She is an experienced researcher in applied mathematics and control theory.The project supports completing her competences with engineering aspects. She will reach professional maturity and further career development. The project supports spreading of knowledge
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Development of the equipment and technologies of radiomagnetotellurics for rapid pollution mapping and monitoring using foot-, car- and boat-borne survey'.

assistant: **Objectives**

The objective of the project is the development of the equipment and technologies of radiomagnetotellurics (RMT) for pollution mapping in water and soil and rapid environmental monitoring in industrial regions. Instruments for the measurement of the fields generated by radio transmitters in the frequency range of 10 to 1000 kHz for foot surveillance (conventional RMT survey) and in the frequency range of 10 to 300 kHz for car- and boat-borne ones will be designed and constructed. Field techniques of foot-, car- and boat-borne measurements will be developed, as well as the processing and interpretation software. The technologies for mapping and rapid environmental control of the pollution of rivers, lakes and near-coast sea waters by various kind of wastes will be developed; likewise waste-sites exploration, localization of waste disposals and hydrocarbons floods and monitoring their flow in soils, dam leakage and fracture zone mapping.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'COMPUTER GRAPHICS ACCESS FOR BLIND PEOPLE THROUGH A HAPTIC VIRTUAL ENVIRONMENT' in the context of a Fifth Framework call.

assistant: **Objectives**

Nowadays, some of the obstacles that impede to blind people to have access to the computer applications are being solved with the use of screen reader software, speech synthesisers, Braille displays or haptic mouses (2D). However there is an inaccessible field yet for them: the 3D computer graphics. The main aim of the project is to eliminate this barrier allowing blind people to access to the 3D graphic computer world through the sense of touch and with audio help, by means of a new Haptic Virtual Environment (HVE). In addition to display the images of a 3D object, the proposed HVE would allow the user to feel with his fingers the shape and tactile surface properties of the virtual object as if he was manipulating a real mock-up of the object. This would be achieved implementing a new Haptic Interface specifically developed to touch 3D virtual objects both with the thumb and the index fingertips while moving the hand in a desktop workspace. The new HVE could serve to develop a great number of training, learning and entertainment systems like the utilities proposed in the project: a training system for the recognition of virtual maps of cities, a system for education and reinforcement of the auditory memory and an application for the development of 3D Haptic Graphical User Interfaces (GUIs) through virtual buttons.DESCRIPTION OF WORKThe proposed HVE is based on the integration of:- a new force feedback haptic interface (HI): capable of replicating independent force vectors at the thumb and the index tip (the simultaneous contact of these fingers with the object would facilitate to the user the recognition of the shape of the objects), with a workspace covering a large part of the user desktop and with a high force feedback fidelity to perceive tiny geometrical details o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Pan-European Research infrastructure on High Performance Computing for 21st century Science' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

High Performance Computing is an indispensable means to solve the most challenging problems through simulation, and the access to HPC infrastructures of advanced class in Europe is vital for scientists to remain competitive at international level.  HPC-Europa++, ensuring the continuity of the ongoing I3 FP6 HPC-Europa Project, has the main objective to provide advanced computational services in an integrated way to the European research community working at the forefront of science.  HPC-Europa++ is organised around its Transnational Access activities (TA), provided by six HPC centres with a clear European dimension and added value in terms of performances and capabilities: CINECA in Italy, UEDIN in the UK (called in this document UEDIN-EPCC, being EPCC the Edinburgh Parallel Computing Center, part of UEDIN and actual subject of the project activity), BSC in Spain, HLRS in Germany, CNRS in France (called in this document CNRS-IDRIS, being IDRIS Institute for Development and Resources in Intensive Scientific computing, part of CNRS and actual subject of the project activity), and SARA in the Netherlands.  The Project delivers a wide spectrum of services, including access to first-class HPC platforms for all European researchers, provision of an advanced computational environment, technical support and training, cooperation at scientific level in a huge variety of research fields.  In one year project life, a total of 136 Researchers will benefit of the TA programme. These visitors will spend at least 200 visitor-months at the different infrastructures, and will use not less than 11.790.000 Allocation Units (AU). The AU is defined as “the computational power delivered by a computer executing for one hour at the sustained rate of one GFlops/s”. The attained results and obj
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Development of a new respiratory tract drug application technology for the treatment of pulmonary diseases'.

assistant: **Objectives**

Research in drug targeting will become one of the most interesting subjects in pharmaceutical in within the next years. By respiratory tract application of drugs, e.g. anti asthmatic substances, antibiotics and secretoly specific targeting and the induction of tissue or cell specific resorption systems is not established moment. An effective drug targeting into the lower respiratory tract or on respiratory tract cells to prove therapeutic effectiveness and reduce the applied dose. Within the proposed project the partners will develop an innovative drug application technology f respiratory tract. The development of specific carrier systems in this extra corporal" part of the bone be easier compared to drug targeting within the organism. The consortium has considerable experience with liposomes and surfactant formulations which X used as specific drug carriers. The first step of the project will be the identification of suitable drugs of different chemical structures used in the carrier systems (liposomes, surfactant) for inhalation. This is a very important step because the wrong selection of a substance or disease for treatment would lead to serious problems in the subject. Besides the use of therapeutic drugs, the consortium will also use the carrier systems for gene therapy of cystic fibrosis. The next step will be the development of stable formulations of different drugs with liposomes anl factant. Cell specificity will be reached by receptor specific ligands which will be integrated into the somes and surfactant formulations. The goal of the project is to establish a new technology which could be used for different drugs and the therapy of different diseases of the respiratory tract and the lung (asthma, infectious diseases cer)."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Episodic Mass Loss in the Most Massive Stars: Key to Understanding the Explosive Early Universe'.

assistant: **Innovation**

Massive stars dominate their surroundings during their short lifetimes, while their explosive deaths impact the chemical evolution and spatial cohesion of their hosts. After birth, their evolution is largely dictated by their ability to remove layers of hydrogen from their envelopes. Multiple lines of evidence are pointing to violent, episodic mass-loss events being responsible for removing a large part of the massive stellar envelope, especially in low-metallicity galaxies. Episodic mass loss, however, is not understood theoretically, neither accounted for in state-of-the-art models of stellar evolution, which has far-reaching consequences for many areas of astronomy. We aim to determine whether episodic mass loss is a dominant process in the evolution of the most massive stars by conducting the first extensive, multi-wavelength survey of evolved massive stars in the nearby Universe. The project hinges on the fact that mass-losing stars form dust and are bright in the mid-infrared. We plan to (i) derive physical parameters of a large sample of dusty, evolved targets and estimate the amount of ejected mass, (ii) constrain evolutionary models, (iii) quantify the duration and frequency of episodic mass loss as a function of metallicity. The approach involves applying machine-learning algorithms to existing multi-band and time-series photometry of luminous sources in ~25 nearby galaxies. Dusty, luminous evolved massive stars will thus be automatically classified and follow-up spectroscopy will be obtained for selected targets. Atmospheric and SED modeling will yield parameters and estimates of time-dependent mass loss for ~1000 luminous stars. The emerging trend for the ubiquity of episodic mass loss, if confirmed, will be key to understanding the explosive early Universe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Exploring the genetic diversity of rice-blast host- pathogen interactions in china: a tool to improve breeding for resistance to blast disease.' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

The objective of the proposed research programme is to identify and characterize genes conferring resistance to the blast disease in Chinese rice varieties and to assess the pathogen diversity for its ability to attack resistant varieties(virulence/virulence). Chinese traditional rice varieties have a large biodiversity and characterisation of this material will lead to the identification of new resistance genes. Three different methods will be used to characterize resistance genes. Virulence genes will be cloned and sequenced and distribution of their alleles studied in the Chinese blast population. This knowledge will beef important value for breeders to introduce the appropriate resistance genes by classical methods or by marker assisted selection to obtain durable resistance. The programme results will be exploited through conventional breeding methods but might also be exploited through transgenic utilization.