RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'RESilient DEMocracies: Rethinking Democratic Resilience through Citizens' Public Connection in Societies Under Pressure' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Democratic societies face a critical challenge: Addressing combined global pressures like climate change, economic instability, and disinformation while preserving democratic norms. As governments work to tackle these issues, the burden of change often disrupts citizens’ lives, leading to democratic erosion reflected in declining institutional trust, rising news avoidance, and growing intolerance. RESDEM addresses a key, yet poorly understood aspect of democracies’ ability to cope with global stressors: citizens’ democratic resilience. The project aims to develop a theoretical framework for understanding this resilience through the lens of public connection, offering a novel approach to resolving the tension between macro-level challenges and micro-level coping processes. Adopting a citizen-centric, practice approach, RESDEM examines democratic resilience as patterned adjustments in individuals’ engagement with public life when faced with disruptions. These manifest in shifting dynamics of attention to public affairs, information-seeking, political discussion, institutional trust, and political participation. RESDEM will conduct a comparative ethnographic study of onshore wind turbine projects in Norway and Germany, representing global issues materializing locally, often sparking grassroots mobilization that can challenge democratic norms. Norway and Germany, with strong institutions and high civic engagement, serve as “most likely” cases for democratic resilience. RESDEM aims to: 1) Identify key components of citizens’ democratic resilience, 2) Determine the interaction between individual resilience and local communication infrastructure, and 3) Identify factors fostering resilience through comparative analysis. The University of Bergen provides an ideal environment fo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Software configuration management framework for networked services environments and architectures incorporating ambient intelligence features'.

assistant: **Innovation**

The main objective of the proposed project is to develop and validate a generic framework for Software Configuration Management (SCM), which will pave the way to the realisation of technically and commercially viable private spaces incorporating ambient intelligence features.For this purpose the project will specify and develop the COMANCHE modular and scalable architecture targeting the provision of consistent, secure, low-cost (low-effort) SCM services across today's heterogeneous, and multi-vendor environments. The realisation of the COMANCHE SCM services framework will be built on an adequate software engineering and knowledge management infrastructure that the project will deliver.The main components of this infrastructure will be the following.- The COMANCHE Knowledge Management Framework which will provide the means for effectively conceptualising, organizing, discovering, and exploiting the tremendous amounts of (currently unorganised and scattered) attribute information, pertaining to software configuration management.- A modular component-based software architecture and an adequate design methodology and tool, which will effectively address the engineering and run-time management of reconfigurable software for ambient intelligent networked services environments.- A formal modelling methodology and a consistency validation framework for capturing and analysing the structure and run-time behaviour of distributed software systems.This approach will aim to preserve the integrity of the target networked services environments in terms of allowing software-configuration error detection and recovery across present complex, and multi-vendor private spaces.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'AddreSsing ThReats for virtualIseD services' under Horizon 2020.

assistant: **Concept**

The growing adoption of cloud technologies and the trend to virtualise applications are inexorably re-shaping the traditional security paradigms, due to the increasing usage of infrastructures outside of the enterprise perimeter and shared with other users. The need for more agility in software development and maintenance has also fostered the transition to micro-services architectures, and the wide adoption of this paradigm has led service developers to protect their applications by including virtualised instances of security appliances in their design. Unfortunately, this often results in security being managed by people without enough skills or specific expertise, it may not be able to cope with threats coming from the virtualization layer itself (e.g., hypervisor bugs), and also exposes security appliances to the same threats as the other application components. It also complicates legal interception and investigation when some applications or services are suspected of illegal activity.To overcome the above limitations, the ASTRID project aims at shifting the detection and analysis logic outside of the service graph, by leveraging descriptive context models and their usage in ever smarter orchestration logic, hence shifting the responsibility for security, privacy, and trustworthiness from developers or end users to service providers. This approach brings new opportunities for situational awareness in the growing domain of virtualised services: unified access and encryption management, correlation of events and information among different services/applications, support for legal interception and forensics investigation.ASTRID will develop a common approach easily portable to different virtualisation scenarios. In this respect, the technology developed by the Project
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'ERA-NET ROAD - Coordination and Implementation of Road Reseach in Europe' (2002-2006) under Sixth Framework.

assistant: **Objectives**

ERA-NET ROAD - Coordination and Implementation of Road Research in Europe will be a three year programme that will focus on initiation and coordination of research relating to the management and operation of the strategic road network. Its objective is, b y March 2008, to have achieved trans-national programmes which are strategically planned, nationally funded and have led to the opening of national research programmes. ERA-NET ROAD is a commitment by 11 National Road Administrations, who between them ma nage extensive research programmes with a combined annual budget of 156M euros, to work in partnership to develop joint research programmes financed through joint funds. It will also assist those National Road Administrations without research programmes to develop them and implement research in a manner that provides European integration. It will bring about a joint vision, programme, targets, funds, calls and will deliver results in a strict timeframe. ERA-NET ROAD is based on the principle that for netwo rking of research activities to be developed, two key processes are required: a management structure within which trans-national joint research activities can occur; and the identification and coordination of appropriate research opportunities and the deve lopment of trans-national joint research activities that will provide added value, followed by the implementation of joint programmes and calls. ERA-NET ROAD is organised into seven Work Packages. The first Work Package relates to the development of the m anagement structure, whilst the remaining six Work Packages relate to coordination of research activities and dissemination of the results. It is anticipated that this will cost 2,513,748 euros and an EC grant for this sum is requested.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'COrrosion PROtective Coating on Light Alloys by Micro-arc oxidation' (CO-PROCLAM) targeting Seventh Framework.

assistant: **Abstract**

Since it does not use any CMR or pollutant compounds, micro-arc oxidation (MAO) also known as plasma electrolytic oxidation (PEO) is a promising technique to replace conventional anodising processes such as chromic acid anodising or hard anodising to improve the mechanical and corrosion properties of valve metals such as aluminium or magnesium and their alloys.Though it has been known for many years, this technique is however still not well adapted to comply with the aeronautical requirements. In fact, one of the major challenge is to grow thin oxide layers (< 10 µm), which exhibit low roughness (Ra < 1 µm) and good thickness homogeneity, the latter being of prime importance when processing work pieces with complex shape.The present program aims at developing a particular technology of micro-arc processing of Al and Mg alloys in order to achieve MAO corrosion protective thin layers that comply with the aeronautical requirements while minimizing energy consumption.A detailed investigation of the process parameters and their influence on the grown ceramic layer will be coupled with the characterization of the layers regarding their microstructure and properties focusing on corrosion protection efficiency.Moreover using fast video imaging and time-resolved optical emission spectroscopy coupled with electrical measurements, a detailed study of the physics of the micro-discharges resulting from the dielectric breakdown will be carried out to shed light on the physico-chemical mechanisms that sustain the layer growth. It is thus expected to determine the response of the micro-discharges, and consequently of the ceramic layer characteristics, to a modification in the process parameters. The perfect knowledge of these mechanisms will then help controlling the process through th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Elucidation of the mechanism of sister Chromatid Cohesion' (2002-2006), addressing dissemination and exploitation.

assistant: **Impact**

Cell division is a fundamental process in the growth and proliferation of all living organisms. This entails the accurate duplication and the faithful distribution of the genome from the mother cell to the daughter cells.For this purpose, the ring-like cohesin complex physically links sister chromatids to prevent their premature separation during cell division. However, despite its importance in chromosomal stability, little is known about the interaction of cohesin with chromosomes.Previous laboratory findings have revealed that cohesin relocates from its initial binding sites and accumulates at sites of convergent transcriptional termination along S. cerevisiae chromosomes. Moreover, while the underlying DNA sequence does not determine the placement of cohesin, changes in the transcriptional status affect cohesin localization, with transcriptional induction of a silent gene resulting in downstream repositioning of cohesin.To elucidate the nature of cohesin binding to chromosomes, this project will investigate the mechanism of cohesin relocation in vivo. Specifically, this study will- characterize the translocation of cohesin upon induction of transcription and- assess the behaviour of cohesin during centromere breathing.This analysis will test whether cohesin relocation occurs by sliding along chromosomes or by reloading of the complex downstream of the initial binding site. To this end, chromatin immunoprecipitation followed by hybridization to a high-density gene chip microarray will be employed.Since cohesin is essential for mediating chromosome stability during cell division, these findings will provide novel insights about the maintenance of genomic integrity and will have significant implications for diseases caused by chromosomal instabilities, including congen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Characterization of the molecular components of synapses in Fragile-X mental retardation syndrome: new insights into the FMRP regulatory mechanisms' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Fragile-X mental retardation syndrome (FXS) is caused by mutations in the Fmr1 gene that codes for the FMRP protein. FMRP is an RNA binding protein involved in mRNA metabolism. The translational dysregulation of a subset of FMRP target mRNAs is probably the major contribution to FXS. A hallmark of the FXS phenotype is the elevated spine density with immature morphology. We aim to understand the causes of this spine dysmorphogenesis by unraveling the molecular composition of synapses in a mouse model for FXS and also get insights into the fine-tune regulatory mechanisms of FMRP. This general aim will be tackled by the following objectives: (i) Characterization of the postsynaptic core proteome of hippocampal and cortical synapses in Fmr1 knock-out (KO) mouse model under synaptic plasticity activation at two developmental stages; (ii) Quantitative analysis of the synaptic mRNAs in Fmr1 KO; (iii) Study the function of synaptic microRNAs on mRNA expression and the role that FMRP plays in this miRNA-regulation, and (iv) identification of the regulatory dendritic translational machinery by isolation of the native Arc and PSD-95 mRNAs, two FMRP targets. These objectives will be approached by a novel combination of high sensitive techniques such as Tandem Affinity Purification (TAP) method, microarrays and RNA pull down in Fmr1 KO and TAP knock-in mouse models. The wide expertise of the host lab in mRNA metabolism and in FXS, the use of well characterized mouse models and the fine design of the experimental work-flow make this project with high rate of success. The main outcomes will be to list the dysregulated mRNAs and proteins in synapses of FXS, if this dysregulation is brain region specific and change during development and what mechanisms behind mRNA translation affect th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Co-creation methodology for biotechnology trust-building measures for improved innovation uptake in the bio-based innovation system' under Horizon Europe.

assistant: **Concept**

The effective application of biotechnology plays a crucial role in building a sustainable European industry, in line with the EU Bioeconomy Strategy and its Progress Report, and contributing to the transformation of Europe outlined in the Green Deal. But despite the enormous potential of biotechnology for contributing to sustainable development in areas such as healthcare, materials, chemicals and food production, the technology is not widely accepted and supported by the general public. This leads to reluctance among industry to adopt and invest in biotechnological solutions, uncertainty among investors, and creates little incentive to eliminate regulatory barriers that prevent implementation. Recognising their concerns is therefore essential for improving the adoption of these technologies. The main objective of the B-TRUST project is thus to develop a transparent and inclusive governance model enabling the application of biotechnology to the bio-based and agri-food sector. More specifically, to (1) inform and create transparency related to consumer and environmental safety, (2) leverage engagement from citizens and other stakeholders, and (3) develop and exchange best practices. This model will be built based on the Theory of Change, to ensure impact while keeping all actors committed, and use co-creation trajectories with civil society and stakeholders as trust catalysts, leading to a set of measures and principles for building trust. The model will be developed and finetuned via four biotech use cases chosen to cover different types of concerns and benefits. Mapping out the real and perceived risks and benefits of these technologies will lead to a comprehensive assessment of the technologies, laying the foundations for general trust-building. Lastly, a forum will b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Protein Kinase CK2 : Functional Properties in Cell Growth and Neoplasia', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Among the hundreds of protein kinases known to date, protein kinase CK2 has been shown to act as an essential component for cell survival. Compelling evidence strongly supports that CK2 is involved in the regulation of cell proliferation. CK2 activity is increased in tumour cells and its catalytic subunit may act as an oncogene, as suggested by a recent observation in transgenic mice. However understanding of its cellular functions at the molecular level remains elusive. The present project aims at an understanding of CK2 functions related to proliferation in normal and cancer cells, with a concerted approach combining complementary expertise's, with the major objectives as follows : 1. Understand the structural and functional organisation of CK2 that governs its activity, its regulation and its specificity. This conducted using is complementary approaches, including a set of kinase mutants and should result in the development of new possibilities to manipulate CK2 functions in living cells. 2. Identify the CK2 subunit genes and develop methods to probe their activity in living cells and to manipulate the expression of the kinase or its subunits in cancer cells. 3. Unravel the cellular proteins which are targets of CK2 in vivo, by using the double hybrid system in yeast. Comparative patterns of CK2 target proteins in normal, cancer cells and human tumours should sheet light on the specific behaviour of CK2 in transformed cells and its possible role in oncogenesis. 4. Understand the role of CK2 in the regulation of specific cell functions related to growth control and cancer (I) organisation of the cytoskeleton and neurite formation; (II) regulation of topoisomeraseII and of topo-II dependent resistance to anticancer agents; (III) cell response to the growth factor FGF-2
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Optimised DYnamics of high voltage powertrains: developing Sustainable Systems for Electric Vehicles', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

As the demand for fully EVs rises due to sustainability and decarbonization efforts, consumers' concerns such as longer driving ranges and quicker charging times must be addressed. To this end, ODYSSEV is developing advanced automotive power converters and optimizing powertrain elements to utilize HV levels and novel electronic topologies.The project centers on a hybrid inverter concept that leverages the benefits of both RC-IGBTs and SiC MOSFETs under various load conditions, aiming for the best techno-economic performance. Innovations include optimizing the HV motor's geometry and topology to avoid issues like partial discharge and current harmonics, and designing a reconfigurable battery pack. This battery pack can be charged at lower voltages (400-800V) and provide higher voltages (1200-1600V) during traction mode. The preliminary design targets a 1200V and 100 kW powertrain, with various scenarios to be analyzed for potential HVs.Additionally, ODYSSEV will innovate in areas such as the on-board charger, system packaging, and overall powertrain control. The project aims to demonstrate this HV powertrain integrated in a real vehicle in real driving tests, thereby providing evidence of reduced costs, losses, and weight for EV manufacturers.The ODYSSEV project involves a consortium of 14 partners from 8 countries, including research institutions, universities, and industrial stakeholders. This group will employ a Safe and SSbD, utilizing virtual environments with PHIL capabilities for cost-effective and efficient prototyping. The consortium has access to necessary facilities and networks for manufacturing, prototyping, and testing innovative automotive solutions.The expected impact includes a 30% reduction in energy losses and a 20% increase in driving range, with sign