RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Laboratory 3D micro X-ray diffraction'.

assistant: **Objectives**

Essentially all materials microstructures are three-dimensional (3D). In spite of this, by far the most widely applied characterization tool is microscopy, which gives 2D images only. There is a need to go to 3D, and daily access to 3D measurements is required. Instruments that can be operated at home laboratories is thus the way forward.Our solution is to use newly developed and commercially available X-ray optics to focus the X-ray beam down to micrometer size in a laboratory X-ray instrument, and adapt measurement principles inspired by synchrotron X-ray techniques to enable nondestructive 3D imaging with a spatial resolution of 1 μm. The resulting laboratory 3D micro X-ray diffraction (LabμXRD) method will outperform all existing tools for mapping crystallographic orientations and be the first of its kind enabling measurements of strain tensors within local microstructural elements.The project objectives are: •to prove the concept and demonstrate the innovation potential of our LabμXRD idea (filed as a patent application);•to validate LabμXRD results, quantify resolution specifications as well as the strain measurement potentials and provide guidelines for LabµXRD measurements for different types of samples;•to complete a first business plan for commercialization.In this project, we will focus on demonstrating the potential of LabμXRD for non-destructive 3D microstructural characterization by the use of metallic materials. It must, however, be noted that LabμXRD can be used for characterization of any crystalline material with grain/subgrain size down to 2 μm. When LabμXRD is manufactured and commercialized at a sales price within reach for leading universities and industries, in the order of 1.5 M €, we foresee that it in time will revolutionize the way materials a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Oscillatory Rhythmic Entrainment and the Foundations of Language Acquisition'.

assistant: **Objectives**

Half of “late talkers”, infants who are not yet speaking by 2 years of age, will go on to develop language impairments. Currently, we have no reliable means of identifying these infants. Here we combine our developmental approach to phonology (psycholinguistic grain size theory), to the neural mechanisms underlying speech encoding (temporal sampling [TS] theory) and our work on the developmental importance of the speech amplitude envelope (AE) to open a new research front in the foundations of language acquisition. Recent adult research confirms our decade-long focus on the importance of sensitivity to AE ‘rise time’ in children’s language development, showing that rise times (‘auditory edges’) re-set the endogenous cortical oscillations that encode speech. Accordingly, we now apply our in-house state-of-the-art methods for measuring oscillatory rhythmic entrainment in children along with our recent theoretical and behavioural advances concerning AE processing to infant studies. Our core aim is to use the TS theoretical perspective and analysis methods to generate robust early neural and behavioural markers of phonological and morphological development: TS for infants. We have published the first-ever studies of oscillatory entrainment to speech rhythm by children and we have developed methods for technically-challenging EEG speech envelope reconstruction. We now apply these innovative methods to infant language learning and infant-directed speech. Using our cutting-edge EEG methods, we will deliver a novel and innovative road map for charting early language acquisition from a rhythmic entrainment perspective. Our recent 5-year study of rise time sensitivity in infants confirms the feasibility of a TS approach. As our focus is on prosody, syllable stress and syllable pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Co-ordinated action of EUROPABIO and NBAs (National bioindustries associations) for the identification and PROmotion of potential industrial participation of SMEs in the 1st Thematic Programme Quality of life and management of living rEsou"'.

assistant: **Objectives**

Co-ordinated action of EuropaBio and NBAs (National Bioindustries Associations) for the identification & promotion of potential industrial participation of SMEs in Community RTD programmes for SMEs such as CRAFT, Exploratory Awards and Cross-Border Co-operative Research. Biotech SMEs in Europe will be informed on the content of the V FP and will be screened on their market and technological needs. EuropaBio will identify potential joint RDT projects with the help of experts. Finally several brokerage and partnering events will be organised in order to increase the quality of research and the participation of Biotech SMEs in Community RTD programmes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Achieve QUieter Oceans by shipping noise footprint reduction' (AQUO) under Seventh Framework.

assistant: **Objectives**

Recent directives outline the need to mitigate underwater noise footprint due to shipping, to prevent negative consequences to marine life. In that context, the final goal of AQUO project is to provide to policy makers practical guidelines, acceptable by shipyards and ship owners. The list of solutions will be split into solutions regarding ship design (including propeller and cavitation noise), and solutions related to shipping control and regulation. Exploitation of the AQUO project results is expected to have significant impacts, meeting the requirements of the MSFD.The project is supported by relevant methods and tools, which will be used to assess the effectiveness of noise mitigation measures in order to select the most appropriate:- A noise footprint assessment tool will be derived from Quonops an existing operational underwater noise prediction system, connectable with AIS shipping data. The tool will be adapted to the problem considered and validated by comparison with in-situ measurements at sea.- Dedicated bio-acoustic studies will be conducted on different marine species representative to European maritime areas, with the goal to derive criteria regarding shipping underwater noise acceptable limits.- Computer methods will be developed and scale model experiments will be done to predict radiated noise from ship propellers, including cavitation effects and interaction with ship hull. These predictive techniques will be validated by comparison to measurements.- To support the analysis, several vessels, including commercial ships, will be tested at sea. Indeed, the project will benefit from the strong expertise of the consortium in the field of ship noise and vibrations, relying on long term experience on many ships, and a dedicated database. A proposal for ship
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Investigation of the underlying resilience and physiological adaptive response of the bona fide Cypriot indigenous grape cultivar cv. ‘Xynisteri’ to climate change' under Horizon 2020.

assistant: **Concept**

The adverse effects of increasingly warm and dry growing conditions are already pushing traditional and new-world wine-growing regions to their limits,. Since the grape-growing potential of their long-established cultivated grape varieties - and consequently the often strictly regulated quality and typicity of their wines - relies on the mesoclimate of their terroir sustaining a high temporal stability, climate change becomes a major threat. Among the adaptation measures considered, the most urgent is the adoption of climate-resilient grapevine varieties. Certain indigenous varieties found on the island of Cyprus, a natural “open lab” of warm and dry climate viticulture, have been reported to have a very high heat and drought tolerance and deserve consideration for cultivation outside their native region of production. However, their resilience remains yet to a large extent scientifically unexplored. To this end, the researcher will carry out a fellowship to investigate the underlying resilience and physiological adaptive response of the bona fide Cypriot indigenous grape cultivar cv. ‘Xynisteri’ to climate change, with an aim to support with sound scientific data its suitability as a variety to be used as a long-term adaptation measure, from countries where their viticulture is already negatively impacted by increasingly warm and dry growing conditions. The fellowship will be carried out in Zambartas Wineries Ltd as the Host Institution, a pioneering SME tightly aligned with regional Research Units, with targeted secondments at leading in the field Institut des Sciences de la Vigne et du Vin, France and University of Tuscia, Italy. The interdisciplinarity and intersectionality of the proposed project will provide the researcher with a unique opportunity to broaden her
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Development of Robust and Innovative Vaccine Effectiveness'.

assistant: **Innovation**

Influenza is a major public health problem. In a conservative estimate, influenza infects annually 60 of the 500 million inhabitants of the EU. Vaccines are the cornerstone for preventing influenza and its consequences. Current influenza vaccines have a moderate variable effect, given the mismatch between vaccine and circulating strains, waning immunity and interference from previous vaccination, among others.The single most important challenge in achieving VE studies for the various influenza vaccines put every year on the European market is the ability of the different stakeholders to work in collaboration.To enable a sustainable network of influenza vaccine VE studies, the Development of Robust and Innovative Vaccines Effectiveness (DRIVE) main goal will be the development of a governance model between public and private entities. This model will ensure scientific independence in the studies and full transparency, allowing different stakeholders to fulfill their needs taking into account their respective obligations and statutes.A second challenge will be to reach the capacity to perform vaccine brand- specific effectiveness studies, which is agile enough to deliver the needed outputs in timely manner, and robust enough to provide results by different age and risk groups and flexible enough to utilize novel tools while at the same time aims to be sustainable.Combining these outputs, DRIVE will establish a sustainable platform for joint influenza vaccine effectiveness evaluation which will have a positive impact on European citizens public health.


**Keywords:** Influenza vaccines, Effectiveness, public-private, Public health, Governance
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Presidency event - Belgium. R&I policies for Better Health, Wellbeing and Prosperity : Policy for Research and InnOvation for better HEALTH' (PRIOHealth).

assistant: **Concept**

Europe is confronted with a multitude of health challenges for which strong research and innovation efforts may bring solutions. The strategies and policies governing R&I, however, need to be harmonized across different levels (EU, national, regional) and transcend geographical boundaries to defragment European research efforts.The need for European cross-border alignment of R&I efforts became particularly obvious during the COVID pandemic. Although there is an immense potential throughout Europe to become the preferred global hub to conduct clinical studies and trials, Europe largely failed to secure this potential. Besides the imminent urgency to provide a response in case of a pandemic, aligning R&I strategies and policies isalso crucial to develop healthcare of the future, which will be personalised and preventive, building on the convergence of cutting-edge technologies, such as bio-, nano-, digital technologies and engineering and integration of several types of data, including genomic data, health data, and real-world data. The transformative potential of such convergence, however, is frequently hindered by the challenge of translating scientific knowledge into practical innovations and effectively incorporating these innovations into healthcare systems as well as the lack of standardisation and harmonisation. The European partnerships and access to high-end research infrastructures play a pivotal role in addressing the fragmentation of European R&I efforts and realising the ultimate goals and ambitions of establishing Europe as a lead region in the world providing R&I-based answers to complex health challenges.


**Keywords:** Pandemic preparedness, One Health, European partnerships for Health
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Bringing Digital Twins to the Edge for mass Industry 4.0 applications'.

assistant: **Innovation**

Digital twins, along with the Internet of Things and Edge computing , are expected to play a decisive role in the next decade’s industrial markets (Industry 4.0) enabling dramatic improvements in complex systems design and operation. However, this technology has not been yet widely implemented, since it requires the collaboration of experts in multiple fields and costly computational tools.The EdgeTwins HPC project brings a different approach that will extend digital twins to new market segments and users (i.e. SMEs). It aims to develop an open-source software tool (builder) to produce digital twins that run on the Edge. That is, they are installed on the physical asset they represent, and operate in very constrained compute environments. This approach will enable a new breed of novel real-time applications, from autonomous vehicles to small devices.The main objective of this FET Innovation Launchpad project is to evaluate the business feasibility of an open-source Digital Twin builder software for Edge applications and develop and test a demonstrator (alpha) for one or more use cases identified in the market analysis. To do so, the participants will leverage on the high-performance computing software stemming of the ExaQute FET Proactive project. These assets will allow, using Reduced Order Modelling techniques, to model complex 4D simulations to later extract the essential features of the solution so that similar results can be obtained at a vastly reduced computational cost.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Identification and role of lysophospholipids in germ cell and heart biology' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Signalling between cells regulates many aspects of their behaviour. Although much work has focused on proteins, bioactive lipids also have potent effects on cells. In Drosophila lipid signalling is implicated in guiding migrating germ cells. The germ cells, which later will become sperm or eggs, undergo a stereotyped migration during embryogenesis to reach the gonad. Enzymes of the lipid phosphate phosphatase (LPP) class are expressed in regions of the embryo that germ cells normally avoid and serve to repel germ cells and regulate their survival. Later in embryonic development these enzymes are also expressed in a subset of Drosophila heart cells and are required for correct development of the heart. These data suggest that extracellular lipids are regulating the behaviour of both germ and heart cells. The aims of this project are several-fold: Firstly to discover the extracelluar lipid that is responsible for the behaviour of these two cell types. Secondly to discern it’s mode of action, in particular what are the molecular players that are necessary to detect this lipid and how they link to known pathways that regulate cell migration. The final goal is to find out if these roles are conserved outside of Drosophila. This research is important because the LPP enzymes are highly conserved in evolution but a full understanding of their function in any developmental paradigm is lacking. Secondly a number of in vitro substrate of LPPs have been shown to have important signalling roles. For example sphingosine 1-phosphate acts extracellularly to influence lymphocyte circulation and endothelial cell migration during vascular development in mice. To what extent LPPs modulate these activities is unclear. Information gained by studying lipids in model organisms will lead to a b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'ERA Chair in Sustainable Futures' (SustainERA).

assistant: **Innovation**

The main goal of the ERA Chair in Sustainable Futures (SustainERA) is to establish a new high-level interdisciplinary research group in the field of Sustainable Futures at Tallinn University (TLU), Estonia. The ERA Chair project has two main goals: 1) to establish an Open Lab in Sustainable Futures research that will facilitate collaboration between different Schools of TLU as well as with various external private and public partners in order to enhance interdisciplinary research and policy development in the field; 2) to build interdisciplinary research excellence, capacity and capability of TLU in the fields of sustainability and non-growth by bringing in new researchers including the ERA Chair Holder and doctoral and postdoctoral researchers. The ERA Chair project will achieve its goals by implementing a five-year Research Strategy comprising five ambitious objectives, which are focused on strengthening TLUs position as an important research centre in the field of sustainability and non-growth research both locally and internationally. The main approach is achieved through interdisciplinary social science research for non-growth. The Open Lab and toolbox is established for public stakeholder engagement to develop educational interventions for sustainability and the research based recommendations for policymakers, organisations and businesses on how to work towards sustainable futures. Numerous training and workshop events will be organised to increase the level of research management and dissemination skills. Impacts of SustainERA are increase in number of R&I talents moving to TLU; increased participation of Estonia and TLU in EU R&D funding programmes; increased awareness of sustainable and nongrowth approaches; increased international, interdisciplinary and inters
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Chemically and Thermally Stable Nano-sized Discrete Organic Cage Compounds'.

assistant: **Innovation**

Shape-persistent organic cage compounds consisting only of covalent bonds are fascinating synthetically targets, because they are studied as hosts for the selective recognition of guest molecules, such as artificial lectins, for catalysis in confined space or for the construction of a new type of porous material. For the latter, the shape-persistency and rigidity of the cage cavity is of utmost importance. There are in principle two existing strategies for the synthesis of shape-persistent organic cage compounds. Strategy I: A stepwise approach by irreversible reactions. Here, the advantage is the chemical stability of the target compound due to the intrinsic stabilities of the formed bonds. The disadvantage of this approach is in general the low overall yield, because the system does not allow any ‘self-correction’ of once formed bonds. This is different for the other approach used in Strategy II: By using dynamic covalent bond formation as synthetic tool, shape-persistent organic cages can be constructed from rather simple molecular building blocks in one step. Here, the yields are usually very high or even quantitatively, because the reversibility of the reaction allows the system to self-correct. Unfortunately, the resulting compounds are more prone to chemical cleavage of the cages than those synthesized by the irreversible approach.Within this project, we will combine the advantages of both strategies to synthesize chemically and thermally stable nano-sized discrete organic cage compounds in a two-step approach in high yields. To demonstrate the versatility and synthetic power of this approach, pure hydrocarbon cages will be synthesized in a few steps in high yields. Finally, this strategy will make for the first time open and closed-shell fullerenes and heteroful