RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'What does it mean to be heterosexual?', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

What does mean to be heterosexual? How do you know if you are heterosexual? Though much research has investigated what it means to be *homosexual* very little empirical research has investigated the meaning of heterosexuality. Furthermore, most people who consider themselves heterosexual have never given this question much thought. However, a number of recent, tragic events (e.g., the murder of Gwen Araujo and the deadly attack by Omar Mateen) show that our perceptions of heterosexuality can have profound ramifications for our self-image and our treatment of transgender individuals, gay men and lesbians. My prior research has pointed to two lay models of heterosexuality that can have important consequences for anti-LGBT prejudice – a model of heterosexuality as a form of biological-purity and a model of heterosexuality as a form of moral purity. Across 14 studies (4 large-scale, representative surveys in multiple countries, and 10 lab-based genuine experiments), this proposed research will verify the biological-purity and moral-purity models of heterosexuality, identify the predictors and associated consequences of these models (Studies 1 – 4), investigate the consequences of the biological-purity model for anti-transgender prejudice (Studies 5 – 7), investigate the consequences of the moral-purity model for anti-gay prejudice (Studies 8 – 12), and investigate whether and how individuals strategically adopt or abandon these models to preserve their values and self-image (Studies 13 – 14).Together, these studies will add meaningfully to our theoretical understanding of sexual orientation and some of the causes of anti-gay and anti-transgender prejudice. On a practical level, they will point to new ways of combating anti-LGBT prejudice, even in some of the most severely p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'An innovative approach of Integrated Wildland Fire Management regulating the wildfire problem by the wise use of fire: solving the FIRE PARADOX' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Wildfires are a major problem for many European societies threatening human lives and property with disastrous impacts particularly at the wildland-urban interface. On the other hand humans always used fire as a tool to regulate nature and traditional use of fire is known in many regions of Europe. The understanding of this paradox, is thus essential for finding solutions for integrated wildland fire management.This concept requires considering the various aspects of fire, from its use as a planned management practice (prescribed fire) to the initiation and propagation of unplanned fires (wildfires) and to the use of fire in fighting wildfires (suppression fire). Prescribed or suppression fires will therefore set the limits for wildfires by vontrolling their spatial extent, intensity and impacts.This is the main approach adopted aiming at the creation of the scientific and technological bases for new practices and policies under integrated wildland fire management and in the development of strategies for its implementation in Europe. Three major domains of related activities were considered: research, development and dissemination.In research, the project will focus on understanding the machanisms and modelling the processes associated with fire, from physics to biology and social sciences. Experimental and sampling methods will be used. The scientific and technical knowledge gathered will allow the development of a technological platform that will integrate the fire model, the temporal and spatial variability of fuels and weather, and the potential ecological and social-economical impacts. Documentation and demonstration platforms will also be extensively used for dissemination, focusing in the development of stategies for public awarness, academic and professional tra
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Auction and Day-Ahead Markets Spikes' (AaDAMS) targeting Seventh Framework.

assistant: **Abstract**

The on-going restructuring and market design processes for the power sector, with its complex objectivesof competition, security and decarbonisation has created a need to understand the drivers of change andthe nature of electricity price dynamics. Since electricity is a unique commodity, not easily storablewith important implications when balancing supply and demand, any imbalances can cause largeand sharp changes in price. Hence, AaDAMS, a project on “Auction and Day—Ahead Markets Spikes”,investigates appropriate modeling, forecasting and risk management techniques for the occurrenceof spikes and abnormal price excursions in electricity markets, focusing upon agent specific as wellas market level data. AaDAMS has a main objective of understanding abnormal pricedynamics observed in wholesale electricity prices looking at the behaviour of generators’auction offers, as well as related parallel objectives concerning the exercise of marketpower in the European Electricity Markets, the potential interaction of strategicbehaviour with new technology characteristics, such as wind intermittency and the effect ofpolicy interventions in market design on price dynamics.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Sustainable energy technology at work: thematic promotion of energy efficiency and energy saving technologies in the carbon markets' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The overall objective of the SETatWork proposal is to undertake thematic promotion of energy efficiency and saving technologies in industry sectors connected with the carbon markets Core actions are:- Identification of concrete projects in ETS Companies (WP3)- Matchmaking events bringing market actors together for project realization (WP4)- Parallel project identification and match-making at CDM markets in Asia and Latin America for the benefit of EU stakeholders- Promotion: Website and newsletter (WP5)- Training of EU industry based in need assessment. Improving competences and awareness on energy efficiency technology options and CO2 handling in the industry (WP5)The expected impact of the action is to facilitate the fulfilment of EU s climate & energy policy goals and at the same time exploiting EU RTD and commercial aspects of the carbon market development. It will lead to initiation of a number of specific projects in industry sectors and provide comprehensive dissemination on tools and examples to broad target groups
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Understanding and designing inorganic materials properties based on two- and multicenter bonds' (MultiBonds).

assistant: **Concept**

A major challenge for the green transition is our inability to rationally design inorganic materials with tailor-made properties. This project will tackle this inability by transforming our understanding of chemical bonding in inorganic materials.Understandable rules based on chemical bonds have greatly advanced chemistry but are missing for most material properties, severely limiting the rational design of materials. Until recently, quantum chemical bonding analysis of inorganic materials has only been carried out on a small scale, making it impossible to derive such rules using machine learning. In addition, quantum chemical bonding analysis primarily focuses on two-center bonds. However, multicenter bonds play a critical role in material properties: For example, multicenter bonds have been held responsible for the superhardness of boron-containing compounds and the unusual properties of phase-change materials. By significantly going beyond my recent results on two-center bonds predicting materials properties with simple machine-learning models, I propose to overcome these challenges. The overarching objective of MultiBonds is to derive understandable and universal rules based on chemical bonds for inorganic materials properties through large-scale quantum-chemical bonding analysis considering multicenter bonds. We will 1) develop and apply innovative automated quantum-chemical methods to compute, for the first time, multicenter bonding indicators on a large scale. The generated database will then be used for 2) developing novel predictive deep-learning models and 3) intuitive human-understandable rules for materials properties. As initial applications, we will focus on phase-change materials with low thermal conductivities, magnetic and hard materials, since their pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Noise abatement using concurrent component-product optimisation' (NABUCCO).

assistant: **Concept**

The Nabucco project aims at setting up a methodology for the low-noise oriented engineering of integrated assemblies such as refrigerators, washing machines or computing equipment. The methodology will include:(a) the definition of standard measurement procedures for the vibroacoustic characterisation of the vibrating or noisy components of the assembly;(b) the implementation of a robust mathematical model for the prediction of the overall noise from the characteristics of the components as mounted on a generic structure which is an average of the type of assembly considered;(c) the translation of the mathematical model into a software aimed at simulating the noise signal of an assembly including components with known characteristics.Nabucco's philosophy is to provide component and assembly manufacturers with a tool easily usable by engineering departments.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Hydrogen Bonding Phase Transfer Catalysis' under Horizon 2020.

assistant: **Concept**

The objective of the research described in this proposal is to develop a new mode of activation for catalysis leading to more sustainable catalytic processes using abundant feedstock materials.  By merging hydrogen bonding and phase transfer catalysis, we propose that hydrogen bonding of an insoluble unreactive anionic nucleophile with a hydrogen bond donor catalyst will form a soluble and reactive entity now capable of carbon-nucleophile bond formation with concomitant release of the hydrogen bond donor catalyst.  This activation mode is applicable to nucleophiles as simple as feedstock inorganic salts enabling challenging asymmetric bond-forming reactions in a general and predictable fashion. Inexpensive lost nucleophiles currently unusable due to poor solubility and reactivity will be reclaimed as effective reagents for asymmetric catalysis. Common inorganic salts such as sodium chloride or potassium fluoride will be transformed into high-value products such as complex pharmaceutical and agrochemical products applying operationally simple and cost effective protocols. Synergistic catalysis whereby hydrogen bonding phase transfer catalysis will work in concert with an additional catalytic cycle will be implemented to introduce new chemical transformations with these feedstock reagents, improve efficiency, and create catalytic enantioselectivity where stereocontrol is absent or challenging. This research will require the development of high performance catalysts and the understanding of catalytic mechanisms applying structural, kinetics, and computational studies. HBPTC is expected to expand the field of catalysis, and rival the efficiency of some of the most active metal, organocatalyst and biocatalyst known to date.


**Keywords:** Hydrogen Bonding Catalysis, Phase T
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Effects of systemic annonacin exposure in transgenic mice expressing normal or mutant human tau protein: role of environment-gene interactions in neuro- degeneration' under Sixth Framework.

assistant: **Concept**

Experimental and epidemiological studies have identified natural substances, such as the acetogenin annonacin, that could be associated with mechanisms of neurodegeneration in some forms of tauopathies. Many mutations in the taugene have also been associated with familial cases of tauopathies, such as the frontotemporal dementias with parkinsonism linked to chromosome 17 (FTDP-17). However, it is still not clear what is the relative contribution of genetic and environmental factors to the observed neurodegenerative changes (neuronal loss and pathological tau aggregation) and how specific genetic backgrounds affect the susceptibility towards the exposure to environmental toxins. The goal of this proposal is to investigate gene-environment interactions using experimental models of Tau-associated neurodegeneration.We propose to determine whether there is a pathogenetic synergy between annonacin intoxication and mutations in the tau gene that lead to FTDP-17. Our proposal will take advantage of the transgenic mouse technology to study the effects of a natural toxin on animal models bearing specific genetic background. The results obtained may also increase our understanding of physiopathogenic mechanisms of major neurodegenerative diseases where a gene-environm ent interaction appears to play a role as is the case of Parkinson's and Alzheimer's diseases. The proposed research project has emerged from a consortium of three groups in Europe (Germany, France, Guadeloupe) in cooperation with an experienced researcher from a developing country (Brazil). The realization of the proposed work will strongly strengthen the infrastructure of cooperation between the European partners and will contribute to the human capacity building in the area of neurodegeneration in Brazil.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'New Enabling Visions and tools for End-useRs and stakeholders thanks to a common MOdeling fRamework towards a climatE neutral and resilient society'.

assistant: **Innovation**

The NEVERMORE project is determined in supporting excellence in climate research and overcoming the current silo approach in evaluating climate change impacts and risks across sectors and adaptation and mitigation policies and measures. To achieve its ambitious goals, the project will develop an integrated common assessment framework consistent across scales for modelling, simulating and evaluating impacts and risks of climate change, as well as policy measures. Climate science and Earth Systems information (1); methods for impacts (2) and risks analysis (3); social knowledge (4) are included in the models for delivering multi-sectoral climate impact assessments under consistent and integrated socio-economic and climate scenarios. The NEVERMORE approach integrates information from physical modelling of impacts and risk analysis methodologies and aligns them across different scales: from national, EU and global scales (in the IAM) to local and regional scales via five case studies (Sitia-Crete-GR, Trentino-IT, Västerbotten and Norrbotten-SE, Murcia-ES, Danube delta-RO) that represent various socio-ecological EU contexts. Consistency among the different scales is ensured by combining bottom-up and top-down approaches. The NEVERMORE assessment framework will be embedded in a practical and user-friendly ICT toolkit, including decision-making tools, designed and developed with and for different stakeholders and end-users involved throughout the project via five Local and a Transnational Council of Stakeholders, by leveraging social innovation frameworks, participatory processes and co-design techniques. NEVERMORE’s ultimate goal is to better understand the interactions between mitigation and adaptation policies and measures to deliver sound technical and policy recommendatio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Artificial Intelligence in Manufacturing leading to Sustainability and Industry5.0' under Horizon Europe.

assistant: **Concept**

AIMS5.0, a collaborative Innovation Action aims at strengthening European digital sovereignty in comprehensively sustainable production, by adopting, extending and implementing AI-enabled hardware and software components and systems across the whole industrial value chain to further increase the overall efficiency.Vulnerability of existing supply chains in crisis shows the need for shorter supply chains and for keeping production in Europe. AI enabled fabs will be given more output and higher sustainability, which makes them more competitive on a global scale. New technologies from IoT and based on semantic web ontologies, ML and AI will help to enable the transformation from Industry4.0 to Industry5.0, to create human-centric workplace conditions and to enable the transformation of European industry to climate-friendly production. Above all, sustainability and resilience will be improved.In essence, AIMS5.0 will deliver:- AI-enabled electronic hardware components & systems for sustainable production- AI tools, methods & algorithms for sustainable industrial processes- SoS-based architectures & micro-services for AI-supported sustainable production- Semantic modelling & data integration for an open access productive sustainability platform- Acceptance, trust & ethics for explainable industrial AI leading to human-centered sustainable manufacturing20 use cases in 9 industrial domains resulting in high TRLs will validate the project’s findings in an interdisciplinary manner. A professional dissemination, communication, exploitation and standardisation will ensure the highest impact possible.For the first time a joint approach for implementing AI and AI-enabled hardware will be developed that overarches different industrial domains. AIMS5.0 will result in lower manufacturi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Nanoplatforms  and Oncolytic viruses for novel cancer immunotherapy strategies' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Immunotherapy is a potential key weapon in the fight against cancer, in general, and Glioblastoma Multiforme (GBM), in particular. Still, a better understanding of how immunotherapy can be leveraged in GBM patients is direly needed. Disease complexity and blood-brain barrier impermeability mean that a standard vaccinology approach will not work. As part of a novel cancer management strategy, this project aims to create more efficacious vaccines using polymeric nanoparticles and self-assembled nanoplatforms in combination with modified oncolytic viruses. We will use biodegradable nanomaterials to protect the OV from body clearance and exploit the intranasal route for efficient delivery to the brain. We will incorporate the IL12 gene into a recombinant adenovirus vector backbone, which will stay under the nanoparticle protection until the drug reaches the tumour microenvironment and is released to reverse tumour-induced immunosuppression. This new strategy offers an efficient alternative to the current standard-of care - i.e. labour-intensive immunotherapy and possibly chemoradiation. The development of an off-the-shelf product, which provides additional anti-tumoral effects at different levels, would significantly prolong the life expectancy of GBM patients. This bioprocess would be scalable for production and compatible with Good Manufacturing Practices. The administration strategies, safety and efficacy of the anti-cancer agent will be validated in animal GBM models. The main training objective is to educate a strongly needed generation of interdisciplinary specialists in tight collaboration with large pharmacological industries, academia, and clinical centres. This will not only educate 14 outstanding early-stage researchers, but also greatly enhance their career pers