RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Broadcast and Multicast Communication Enablers for the Fifth-Generation of Wireless Systems' (5G-Xcast) under Horizon 2020.

assistant: **Objectives**

5G-Xcast will devise, assess and demonstrate large scale immersive media delivery by means of conceptually novel wireless technologies, contributing to the further definition of 5G and its standardisation. 5G-Xcast will focus on large scale media distribution, as this use case is one of the most demanding requirements in terms of data rate (capacity), scalability (cost-effectiveness) and ubiquity (coverage). The 5G-Xcast media delivery solution will have built-in unicast/multicast/broadcast modes and caching capabilities. The project will take a holistic approach in order to harmonize media delivery across the three communication modes being considered, and to provide a seamless user experience, as well as common Application Programming Interfaces (APIs) to content service providers. The project will cover multiple disciplines from the radio interface to the transport and application layers, including protocols and APIs, as well as network and system architecture aspects. The development of the 5G-Xcast media delivery solution will be focused on the Media and Entertainment (M&E) vertical. The automotive, Internet of Things and public safety verticals will be considered to ensure that their respective technical requirements are also identified and suitably addressed. Proof-of-concept prototypes and technology demonstrators are pivotal tasks of the project. Special emphasis will be given to emerging new immersive media services that cannot be efficiently delivered by existing technologies and networks. 5G-Xcast will enable progressive convergence in the media delivery sector while optimising the resources of the available infrastructures, enabling new business models over fixed, mobile and broadcast networks that will be also investigated in the project.The consortium is
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Characterization and monitoring of vigilance fluctuation in disorders of consciousness' (ADOC).

assistant: **Innovation**

This prospective exploratory study will aim at characterizing vigilance fluctuation in patients with disorders of consciousness (as defined by a change in diurnal behavioral response over time) using neurophysiological parameters. We based this project on the assumption that changes at the Coma Recovery Scale-Revised scores (i.e., behavioral responsiveness) will be associated with a change in ocular measures and EEG complexity, suggesting that some of these parameters could be used for monitoring vigilance in this population. We expect that this fluctuation will be particularly marked in patients with a minimally conscious state as compared with patients in an unresponsive wakefulness syndrome who will display a more stable pattern of response over the two days. This project aims to better understand the course of vigilance fluctuation in DOC and to develop an objective tool based on biomarkers that could be used at bedside to determine the best periods to assess and treat these patients.


**Keywords:** vigilance, behavioral assessment, consciousness, electroencephalography, eye response
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Modeling signaling pathways in cartilage degeneration'.

assistant: **Innovation**

Osteoarthritis (OA) and Rheumatoid Arthritis (RA) are painful and debilitating diseases characterized by cartilage degeneration, swelling, and decreased function of the synovial joints. It is the leading cause of disability in the developed countries affecting one of every six people and resulting in a significant cost on health and social care systems. Cartilage degeneration can be characterized by the imbalance of a complex network of regulatory proteins. Interleukin-1 (IL-1) and Tumour Necrosis Fact or-alpha (TNF-alpha) are two major cytokines responsible for the pathogenesis of arthritis. Current pharmaceutical interventions are based on the inhibition of these pro-inflammatory pathways. This project utilizes a multidisciplinary approach characterized by the fusion of two seemingly different areas: Biomechanics and Systems Biology. The biomechanical approach will be used to monitor the degradation of cartilage explants by measuring alterations on the mechanical properties. Indentation tests will be combined with biphasic finite element models in order to measure the Young's modulus and the permeability of the tissue.The systems biology approach will be employed to investigate the possible cross-talks of several signalling cascades that govern cartilage degeneration (i.e. TNF-alpha, IL-1, FasL). The measurements of several intracellular and extracellular protein concentrations as well as their activity state will be correlated to the alteration of the mechanical properties of the tissue by using a statistical approach such as principal component analysis and partial least squares regression. Predictive models between signalling network activities and phenotypic outcomes will be derived. The multidisciplinary approach of the project will shed light into the molecular
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'AMBIent Temperature AnaeROBIC Treatment of Municipal Sewage Wastewater' in the context of a Horizon 2020 call.

assistant: **Objectives**

Introducing a breakthrough product innovation, AMBI-ROBIC®, a disruptive Anaerobic Digestion process. For the first time, this technology can be used to treat municipal sewage wastewater at ambient temperatures. In this patent-protected process, unique psychrophilic (cold-loving) microbes’ breakdown and convert pollutants in the sewage to renewable biogas enabling the process to perform at ambient wastewater temperatures. (ambient definition: environmental conditions, existing in the surrounding area).The AMBI-ROBIC® innovation offers many benefits for municipal utilities, driven to change by regulatory drivers – EU UWWTD mandates high-quality treatment and the new European Green Deal will mandate further dramatic reductions in carbon emissions. •High treatment efficiency in terms of pollutant removal at the primary/secondary treatment stage; •>80% less electricity consumed compared with the competition;•No organic sludge production: Reduction in sewage sludge transportation & disposal costs;•High-quality biogas by-product: 100% available for heat, power, fuel cell or vehicle fuel generation; •Carbon Impact: 88% less carbon emissions than competition;If implemented across 10% of the EU’s sewage treatment plants, the carbon impact would be equivalent to 282,000 cars removed from our roads. The proposal addresses the following Green Deal goals:•Increasing the EU’s climate mitigation and/or adaptation ambition•Transitioning of industry to a clean and/or circular economy (including waste prevention and/or recycling)•Preserving and restoring ecosystems and biodiversity•Realising a zero-pollution ambition and a toxic-free environmentThe overall result is an urgency within the municipal wastewater industry to change, adopting innovative low carbon and low energy treatment meth
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The Interplay of Large Scale Structure and the Cosmic Microwave Background Radiation' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The Cosmic Microwave Background (CMB) radiation was released when the universe was only 380,000 years old, and since then it has been propagating through the entire visible universe until reaching us. In its journey, the CMB witnesses how the first stars formed, contaminating the inter galactic medium with the first heavy elements, how the Large Scale Structure (LSS) was assembled through gravitational interaction and how the universe has recently entered a phase of accelerated expansion. All these episodes have left their imprint on the intensity and polarization anisotropies of the CMB, by means of either resonant or Compton scattering, atomic and molecular collision emission processes, and blue/red-shifting induced by gravitational potential wells in the LSS. Therefore, a joint study of CMB and LSS constitutes a crucial tool for understanding those largely unknown episodes, and goes timely with the outcome of CMB experiments like ACT or PLANCK, and LSS surveys like BOSS, J-PAS or EUCLID, in which the candidate is participating. Here we propose a combined study of the optical data to be provided in the next few years by the J-PLUS/J-PAS surveys with CMB multifrequency maps (either from WMAP or those being currently produced by PLANCK): our goal is to address the problems associated to Dark Energy and the accelerated expansion of the universe (by looking at the Integrated Sachs-Wolfe effect and the galaxy cluster/group abundance versus redshift), the universal thermal history and the search for the local missing baryons (by cross correlating the electron distribution traced by galaxy catalogs with CMB maps). The timing of this project fits perfectly with the analysis and data release of both J-PLUS and PLANCK surveys, and provides both data legacy and expertise in prep
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Connecting Energy National Contact Points in a pro-active network under Societal Challenge 3 ‘Secure, clean and efficient energy’ in Horizon 2020'.

assistant: **Concept**

C-ENERGY 2020 V2 is a 18 months Coordination and Support Action having the specific objectives: 1. to improve the knowledge and skills of the Energy NCPs, particularly of NCPs in those countries that have been participating at low levels in the programme up to now;2. to raise the general standard of support to programme applicants and simplify access to Horizon 2020 calls for newcomers and applicants from widening countries by supporting the provision of a high quality, professional Energy NCP services for Horizon 2020; 3. to facilitate transnational cooperation amongst Energy NCPs including non-beneficiaries. C-ENERGY 2020 V2 will capitalise on relevant activities of the previous NCP network project in the Energy sector (C-ENERGY 2020) and those of the NCP Academy.  C-ENERGY 2020 V2 will be carried out by a consortium of 18 beneficiaries, 16 of which are from EU Member States and 2 from Associate Countries to Horizon 2020. Several widening countries are partners of the project (Bulgaria, Croatia, Cyprus, Estonia, Latvia, Poland, and Portugal). C-ENERGY 2020 V2 will organise at least 4 webinars, 2 trainings, 1 Masterclass and 1 twinning . The applicants will benefit of at least 2 brokerage events and 3 training for stakeholders. The project will also take special care of outreaching activities by extending the collaboration with other NCP thematic networks and cooperating with EEN. Finally, communication within and outside the Energy NCP network will be ensured through the website, the promotional materials, social media and the participation at major events. Throughout the project special attention will be paid to those countries that have been participating at low levels in the programme up to now and to the diversity of stakeholders in the energy sector.


**Keywords
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Enhancing and Evolving INFRAFRONTIER Disease Modelling Capacity to Enable Breakthrough Research' (INFRAPLUS), addressing dissemination and exploitation.

assistant: **Impact**

In response to the HORIZON-INFRA-2023-DEV-01-03 call, INFRAPLUS aims to expand INFRAFRONTIER's capacity for human disease modelling, refine its service portfolio by reducing animal usage and developing alternative cellular models, and optimise the use of resources. INFRAPLUS seeks to achieve several objectives: Developing national node capacities and expertise for providing innovative in vivo, in vitro and preclinical services, developing novel model systems and services to meet the demands of existing and novel user communities, and reducing environmental impact.To achieve these objectives, INFRAPLUS will focus on launching pilot services, refining new technologies, emphasising alternate cellular models, designing and implementing special training programmes and optimising resources for the entire consortium. The project includes a defined service development strategy supported by a strong IT and data management backbone and is built upon the needs of the scientific community. Ultimately, INFRAPLUS will enhance and evolve INFRAFRONTIER's capacity for modelling human diseases and enable breakthrough research by providing researchers cutting-edge tools and services to respond to global biomedical challenges.


**Keywords:** Mouse, rat, cells, disease, models, CRISPR, environmental impact, staff capacity, in vitro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Process intensification towards sustainable wastewater treatment with phototropic biofilms'.

assistant: **Concept**

Improving current biological wastewater treatment (WWT) plants towards more sustainable solutions is a priority of the EU (Water Framework Directive). Conventional activated sludge technology faces some challenges such as high O2 demand and inevitable CO2 emissions. Phototropic microorganisms offer a sustainable way of WWT by converting CO2 to O2 and valuable biofeedstock which can further be converted to bioenergy. Photogranules are compact spherical biofilms which contain high amounts of phototrophs in addition to heterotrophs. As a result,  photogranule based WWT can couple CO2 and O2 fluxes from different microorganisms leading to an aeration free WWT. However, to utilize the true potential of this technology, revolutionary reactor designs together with more fundamental understanding on photogranulanation is needed. This work aims to intensify photobioreactors for WWT by using a multidisciplinary approach which combines microrhelogy and microbiology with mass and photon transport models. To have more control over growth and light, novel supports for biofilms will be designed. In addition, the project will explore the relationship between environmental conditions such as light availability and shear on microbial community composition and structure in complex phototropic biofilms by both microfluidic experiments and mathematical models. The information obtained from these studies will be translated to a macroscopic level using simplified transport phenomena models to design an efficient photobioreactor. The findings of this study will both advance our understanding of phototropic biofilms and pave the way towards industrial-scale sustainable WWT. With this project, I am aiming to combine my background on design and modelling of light-driven multiphase systems with the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Sustainable farming of European catfish (Silurus glanis) for innovative, resource efficient and eco-friendly pond farm production' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Today over 70% of world fish stocks are fully exploited or are already overfished. It is a trend since 1990s that capture fisheries production is stagnating, while aquaculture production is expanding. A European citizen consumes 17.56 kg seafood and freshwater products of untraceable origin yearly in the EU, while 57% of the total consumption is imported mainly from China and Southeast-Asia. There is a growing demand for fish products which can only be filled by aquaculture products while health and environmental concerns are raised due to aquaculture products originating from heavily contaminated geographical areas containing mercury, PCBs and other harmful substances. Sustainable aquaculture - fish farming - is needed to provide fresh, high-quality, local supply of healthy products which follows strict rules to protect the consumer, the fish and the environment.Fresh water fish comes in second after seafood products, however in the landlocked countries of Europe (Hungary, Czech Republic, Slovakia, etc.) freshwater fish consumption is traditional and pro vides a stable market which will stay so until 2030 according to recent statistics. Although common carp, as the traditional product of Central and Eastern European fish farmers, has a stagnating market with very low potential for growth.Our company, Aranyponty Halászati Zrt. is one of the biggest freshwater producers in Central Europe and we are one of the first private companies in operation since 1989. We have full-scale fish farm system of over 1500 hectares at Retimajor, operating a high standard fish hatchery and a number of wintering ponds. Our quality assurance system grants high-quality, local product traceable from egg to plate.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Deconstructing adaptive evolution of metastasis'.

assistant: **Concept**

Adaptmet aims to develop an advanced training program encompassing the multifaceted aspects of metastasis adaptation mechanisms, intending to equip budding researchers with the necessary skills to emerge as leaders in this field. A robust mentoring and training strategy, coupled with cutting-edge methodologies and a diverse range of complementary soft skills, are crucial to this endeavour. These skills are imparted through local and network-wide events, fostering seamless research progression, and nurturing successful career trajectories. Scientifically, Adaptmet addresses an unmet medical need by harnessing basic science to revolutionize drug development and, ultimately, enhance patient care. Specifically, scientific work packages (WPs) have been designed to approach metastasis from various functional perspectives. In order to metastasize, cancer cells must adeptly coordinate diverse cellular functions (Cell Fate - WP1). Additionally, understanding the intricate interactions between metastatic cells, the host immune system, and tissue stroma is pivotal (Environment – WP2). Crucial aspects such as the kinetics of metastasis and the mechanisms governing latency, particularly, remain inadequately understood (Latency – WP3). Clarifying this complexity, unravelling mechanisms underlying therapy failure, and identifying expansion pathways are central to defining novel therapeutic targets (Expansion – WP4). In essence, Adaptmet stands at the intersection of a rapidly evolving multidisciplinary domain, amalgamating distinct fields that often face challenges in mutual communication. The success of Adaptmet hinges upon robust partnerships, open exchange of ideas, state-of-the-art methodologies and equipment, and the exploitation of synergistic opportunities among network members