RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Software re-use: a process improvement experiment at an IBM Semea facility' (SURF), addressing dissemination and exploitation.

assistant: **Impact**

Within IBM Semea, the Product Development unit produces software intensive products and solutions for a very dynamic and competitive market, in which product quality, products costs, time-to-market are key competitive levers. To quickly develop high-quality, cost effective solutions for its international customers, the Product Development unit has identified, through a preliminary assessment of its current software development practices, a 1st-priority improvement step in its development process. Such improvement consists in the adoption of a re-use oriented software development practice.THE EXPERIMENTTo achieve this goal, a specific methodology, namely REBOOT, and a supporting tool, namely EUROWARE, have been identified as the key enablers. IBM Semea, Product Development Unit intends to introduce both of them in its organisation, to validate and disseminate them and to measure the actual benefits through a pilot application which is based upon 2 specific baseline projects: Datavideo, the source of re-usable components, and Datasat, which will benefit from such re-usable components.EXPECTED IMPACT AND EXPERIENCEIn the context outlined above, the expected business impact at IBM Semea, PD Unit are:To reduce the development costs of new products and solutions, thanks to the availability and use of existing re-usable software components. The goal is to reduce such costs by at least 25%. To reduce the evolution and maintenance of existing products and solutions, thanks to the use of consolidated, validated, well designed and well documented software components. The goal is to reduce such costs by at least 25%.To reduce the time-to-market of new products and solutions, thanks to the availability of re-usable, tested software components which will reduce the overall design/dev
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'SDD-AGE-MS: a proteomics tool for characterizing protein organization and plasticity in biomolecular condensates.' (SDD-AGE-MS).

assistant: **Concept**

In living systems, biological processes are orchestrated by proteins organized into dynamic assemblies. Cells regulate protein assembly and disassembly through various mechanisms, with subcellular compartmentalization playing a critical role in creating a microenvironment that control biological reactions. Notably, not all compartments rely on membranes for segregation; biomolecular condensates, for example, are membraneless organelles formed through a network of multivalent interactions. While noteworthy progress has been made in identifying the proteins partitioning in biomolecular condensates and understanding the forces driving phase separation; how proteins interact forming assemblies within condensates remain poorly understood. This knowledge gap is primarily due to the lack of system-wide approaches capable of effectively characterizing condensates, which are often low in abundance, large, dynamic, and highly heterogeneous.In this study, we introduce SDD-AGE-MS, an innovative proteomics method designed to characterize the architecture of condensates. By integrating SDD-AGE, an electrophoretic technique commonly used to visualize SDS-resistant high molecular weight assemblies, with mass spectrometry (MS), we aim to map the migration profiles of SDS-resistant proteins and link them to protein assemblies.This project will make significant contributions on multiple levels: (i) conceptually, by unveiling and resolving sub-assembly organization of condensates; (ii) methodologically, by introducing a system-wide approach for characterizing high molecular weight assemblies in cells; and (iii) translationally, by providing insights into the mechanisms driving condensate formation and their transition to pathological aggregates, as observed in neurodegenerative diseases.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'GeneTime: An interdisciplinary training site in Ancient Biomolecules' (GENETIME) under Sixth Framework.

assistant: **Objectives**

We propose an inter-institutional, interdisciplinary training centre dedicated to the recovery of information from ancient biomolecules, GeneTime. The study of ancient biomolecules is a vibrant and innovative new interdisciplinary research area, with important scientific and cultural implications. Small, fragmented bimolecular remains have proved to be storehouses of past information, and their analyses can provide a window to the past, yielding information that is both of relevance and fascination in modern Europe, and its peoples. Ancient remains (museum skins, fossil bones, dried animal dung, blood stains, and even ice and sediment samples) contain records of genetic diversity and histories of both extinct and living species in the form of preserved DNA and proteins. With the right technologies this record can reveal novel data about how fauna and flora have responded to climate change and migration events, and identify key genetic and behavioural adaptations. In addition, early domestic specimens hold potentially valuable information about the changes in genetic diversity and dietary behaviour that produced modern domesticated animals and plants. Europe is the world leader in this uniquely exciting new area of research but due to the speed of methodological development and the extreme interdisciplinary of the field, training and resources are fragmented within and between countries. Centres of excellence do exist and GeneTime attempts to link to together four of these. Each institute has a particular research advantage, and by combining them the sum will be far greater than the parts. This will form a unique, high profile early training site, unparalleled in scope and seeking to share benefits of training and research
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Holistic integration of eco-Friendly dEsign tools, mateRials, fabrication technologies for the responsible co-creation of future Sustainable integrated electronic systems', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The FERNS Doctoral Network will train a talented cohort of 15 Doctoral Researchers (DRs) to embed circular approaches into electronics design in support of the mutual reinforcement of the EU’s Green and Digital transition ambitions. The generation of e-waste and depletion of critical raw materials associated to the intensive use of electronics call for urgent interventions to embed circularity into future electronic products. In answer to this call, the FERNS project brings together ten partners and 9 associate partners with expertise across the entire electronics value chain to address the key challenges underpinning the field of sustainable electronics. FERNS aims to incorporate eco-design and co-creation in the electronic products development phase; develop novel sustainable materials and integration processes for next generation sustainable electronics, targeting three specific application areas (Fitness, Short Use Health and Farming); create novel models promoting societal and economical acceptance and appropriation of sustainable electronics. The FERNS DRs will meet these ambitious objectives by working creatively and synergistically across the disciplines of material science, engineering, social science and business to acquire a holistic perspective of the field of sustainable electronics. The FERNS Doctoral Network merges research excellence with comprehensive (technical and transversal) training and exposure to industry to address a critical skills gap in sustainable and circular electronics expertise, which must be addressed urgently to drive and accelerate the EU’s transition to Circular Electronics, as demanded by the Green Deal overarching strategy, aiming to achieve climate neutrality by 2050. In parallel it builds momentum in ‘looked for’ skills in emergi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Electric Field eFfects In Chemistry And CatalYsis' in the context of a Horizon Europe call.

assistant: **Objectives**

Chemists constantly seek better catalysts that improve performance of desired chemical reactions and suppress the formation of adventitious products. On the other hand, Nature performs difficult reactions using tailored electric fields as catalysts, and so can we! The overarching goal of this project is to impose, measure and utilize microscopic electric fields to fundamentally understand their organization and elucidate their role in driving non-redox chemical reactivity and catalysis.EFFICACY uses the electric double layer at polarized solid-liquid interfaces to impose strong microscopic electric fields. Despite significant advances in measuring fields projected onto marker vibrational modes (vibrational Stark effect), gaining understanding of the topological complexity (directions, spatial variation) of the three-dimensional electric field vector with Angstrom resolution in its dynamic evolution remains a formidable experimental challenge.EFFICACY develops a suite of approaches to sense microscopic electric fields based on time-resolved vibrational multidimensional Stark probing and excited-state symmetry breaking in tailored molecular probes. EFFICACY implements ultrabroadband femtosecond infrared (IR) light source capable of simultaneous excitation and probing of many vibrational and electronic transitions across the mid- and near-infrared spectrum.EFFICACY explores electrostatic catalytic effect in a selection of novel photoreactions using multiscale time-resolved IR spectroscopy spanning many orders of magnitude in time. Ejection of small molecules from novel classes of organic compounds and alkyne-allene photoisomerization aim to understand the through-space field effect on bond-breaking/formation and intramolecular reorganization events. The idea of alternating
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Genetic analysis of planar polarity in the adult eye of drosophila melanogaster'.

assistant: **Concept**

Research objectives and content Tissue polarity is a fundamental property of cells. In adult cuticle of Drosophila melanogaster, polarised structures, such as bristles and hairs point posteriorly on the thorax and abdomen. The molecular basis of tissue polarity has hardly been studied and any progress in understanding will have considerable scientific impact. Experiments in Drosophila have supported earlier suggestions that tissue polarity might orient in response to a vector of a gradient of a diffusible morphogen. In spite of recent efforts to identify new tissue polarity genes, the nature of the polarity signal has remain elusive. The eye allows a new approach to this problem. I plan to study the mechanisms of cellular polarity by (i) systematically identifying genes whose products are essential for the specification of polarity in the dorsal and ventral haves of the eye and (ii) characterising the products of these candidate loci. The devised strategy to identify these genes allows the rapid scoring of a polarity phenotype in live flies. The method includes the use of silencer-trap lines that label the position of the equator in the adult eye of the living fly. Mutations will be selected by their ability to alter the expression and position of the equatorial lines in living flies. Training content (objective, benefit and expected impact) My primary goal is to identify new genes responsible for polarity as well as to discover any roles of known genes in polarity. I also hope to learn new methods of developmental genetics and molecular biology that will enable me to tackle any issue in developmental genetics in my future research work. Links with industry / industrial relevance (22) The project will have no direct link with industry, but any progress in understanding
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on '“Synthesis and biological activity of Cu(II) metallonucleases that target tumour cells”'.

assistant: **Innovation**

Dr. Diego Montagner, an Italian national who is working as a postdoc in the group of Prof. B. Longato (Padua University), is making an application to this programme to move to NUI Galway in Ireland, where he is currently spending a period as Visiting Scientist in the group of Dr. A. Erxleben, to carry out a project for 24 months in the area of medicinal inorganic chemistry.This proposal specifically deals with the synthesis of Cu(II) complexes that selectively target tumour cells and act as artificial metallonucleases, i.e. cleave the DNA of the tumour cell through a hydrolytic mechanism. Specific carrier molecules such as estrogens will be conjugated to the complexes to increase the selectivity. The catalytic activity will be tested studying DNA models (like simple phosphate diesters with good leaving groups), short oligonucleotides and supercoiled plasmid DNA. Biological tests will be performed on different tumoral cell lines, including cisplatin-resistant ones.The fellow has already an excellent background in coordination chemistry and this project will allow him to deepen and expand his skills in organic synthesis. He will learn new analytical techniques and at the final stage of the project he will enter into the biological field. Besides contributing to his overall scientific growth, this experience will be important for his long-term plans to focus his research interests on biological aspects of medicinal chemistry, such as drug-biomolecule interactions.He proposes to join NUI Galway which is strategically developing strength in Biomedical Research and Cancer, a very important and challenging branch of Chemistry/Biochemistry research in Europe. NUI Galway will also provide training in transferable skills and mentoring to Dr. Montagner. Both the scientific and per
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Authentication of meat products using ambient surface mass spectrometry' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The research objective of the project is authentication of meat products using ambient surface mass spectrometry : desorption electrospray ionization (DESI) and plasma-assisted desorption/ionization (PADI) mass spectrometry.In recent years, authentication of meat products has been gaining in practical importance throughout the world due to economical reasons, religious and moral objections. Adulteration can be also hazardous due to occurrence of food allergies to meat proteins.Implementation of effective techniques such as DESI and PADI that could be applied without preliminary sample preparation will be a breakthrough in meat products authentication. This will result in a novel, fast, innovative method that will allow analysis of complex meat products (e.g. sausages, canned products).For this purpose a multidisciplinary team spanning researchers with different backgrounds was build: Prof. Barret (scientist in charge) has expertise in analytical bioscience, Prof. Alexander in characterising organic surfaces, Prof. Tucker in molecular biology and food authentication, the applicant has experience in food science and proteomics. The School of Pharmacy at the University of Nottingham has an international reputation for its research in surface analysis and expertise in state-of-the-art biochemical analytical technologies.The collaboration will result in integration of the applicant into a highly competitive international research group. The resulting training will enhance the applicant individual competence diversification and will deliver high quality career development in attaining a leading independent position in education with wide applicability across the EU.The project will contribute to improving food safety and to reduce cases of adulteration. The results will have
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Eco-innovative building products for sustainable construction in a circular economy'.

assistant: **Objectives**

Criaterra develops regenerative construction materials and products to enable the transformation of the building industry into a circular economy. Globally, construction and the use of building materials account for 50% of extracted materials, 50% of its energy consumption, 33% of its water consumption and 33% of all waste generation. The construction material manufacturing process incinerates virgin materials, changing their natural properties and rendering them non-biodegradable and eventually problematic waste. This resource-intensive process is a massive CO2 emitter, and revolutionizing it is a key EC priority. The circular economy represents a €4 trillion opportunity however, with a global economy that is only 9.1% circular, there is a massive circularity gap.  Redesigning the entire lifecycle of building products and their production methods is central to reducing the environmental impact of the construction industry and developing a circular economy. Criaterra’s disruptive innovation produces products using minimal energy (90% energy savings compared to ceramics), generate minimal emissions (97% GHG savings compared to concrete), are manufactured from up to 70% recycled materials and are 100% recyclable and 100% biodegradable. They have the strength of concrete and very low thermal conductivity. They dramatically reduce the energy consumption, waste stream and CO2 emissions of the built environment. The global green building materials market size is expected to reach €323 billion by 2022 rising from 170 billion in 2016, at a CAGR of 11.2%. It is Criaterra’s goal to use this opportunity to become a leader in developing circular, regenerative materials using low embedded energy production practices in construction. Criaterra’s 2-year innovation project expands the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'AvantDante: the Reception of Dante in 1945-2001 US Avantgarde Poetic Communities', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

AvantDante offers the first systematic study of the translation and reception history of Dante Alighieri’s works and persona in the US avantgarde poetic communities between 1945-2001. The variety of poetic practices that emerged over this period is characterized by an experimental approach to composition and a sensitivity to the resistance of a text to closure, through extensive use of translation, parody, and pastiche. This project adopts a reader-oriented perspective and a transdisciplinary methodology to argue that the conspicuous degree of interaction by avantgarde poets with the figure and works of Dante constitutes a means to community creation, at a time when responses to (including rejection of) dominant and received modes of poetry was performed through an eclectic engagement with the modernist cultural legacy and a metatextual reflection on poetic language itself. AvantDante makes use of archival and digital tools to revivify a heterogeneous corpus of print evidence  from public, national, and university libraries, special collections, and archives in the US; it deploys elements of philological and textual analysis to explore cultural metamorphosis, reappropriation, translation, and transmission; and it blends literary, socio-historical, material and digital approaches to map, visualize and convey an innovative and comprehensive reconstruction of these avantgarde movements as eclectic circles or communities of readers and mediators of Dante. Further, in exploring cultural appurtenance, linguistic identity, and translation practices through a lens of Dantean reception, problematising the larger project of constructing a specifically “American” literary idiom and explicit or implicit dialogue between poetic communities, this research will provide the first liter