RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Towards pediatric molecular imaging: development of a low-dose and high-performance Total Body PET scanner' in the context of a Horizon Europe call.

assistant: **Objectives**

PositrPositron Emission Tomography (PET) constitutes the imaging modality of excellence in nuclear medicine. Conventional whole body (WB) PET are used for both adult and pediatric studies. However, these scanners are not large enough to image the entire infant body, are not optimized in terms of sensitivity imposing the injection of high radiotracer doses and their spatial resolution is as best 3-5 mm at the center of scanner, which is not enough for visualizing small lesions. Moreover, since PET imaging requires the injection of a radiotracer compound, its use is compromised in pediatric due to radiation regulations and patient safety.To overcome these limitations, I aim to develop an affordable high-performance, high-sensitivity total body (TB)-PET for pediatric imaging. The system, named PHOENIX, targets for a high effective sensitivity of x25-30 the one of clinical WB-PET. To achieve this goal, we propose a large axial scanner of 54.5 cm with a bore diameter of 32 cm to cover all organs of children -without becoming claustrophobic- and, thus, permitting for dynamic multi-organ studies.For the best cost-performance tradeoff, the PHOENIX detectors would be based on semi-monolithic BGO crystals coupled to SiPMs. This design allows characterizing the light distribution profiles to retrieve photon depth of interaction information (resulting in a uniform image spatial resolution <3 mm) while simultaneously providing time-of-flight (TOF) capabilities. To offer significant TOF information, I aim to exploit the low Cherenkov light yield produced in BGO. We will implement a scalable custom readout circuit composed of 3- stages: i) signal multiplexing, ii) event classification -Cherenkov and Scintillation-, and iii) commercial ASIC adaptation for digitization.Developing the PH
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Revisiting Europeanization in Southeast Europe. An Historical Approach', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The future of Europe will vitally depend on its ability to transform and unify the continent. Southeast Europe, with its complex historical trajectories and its own particularistic Europeanness, has been labelled difficult to Europeanize. Yet, Europeanization in Southeast Europe has a far longer history reaching back into the 19th century and earlier. The main goal of the RESEE project is to establish Europeanization research on the Southeast Europe as a complex historically grounded process, firstly through developing a meaningful narrative integration of the prevailing knowledge in the historical dimension of Europeanization of Southeast Europe; secondly through discussing the usefulness of Europeanization and its related process bringing historical cases of how Europe has influenced Southeast Europe and vice versa; and thirdly through tracing the process back we build an explanatory model that maps the events and actors, the causal mechanisms and factors that interact when a specific historical Europeanization process unfolds in Southeast Europe.RESEE is an innovative project studying a long and much disputed ‘European otherness periphery’ contributing to the rethinking of the region in such a reflexive way that it have meaning and utility in the current EU political project of European Integration. RESEE main academic outputs include a Living Review on the literature, a course proposal and a workshop on the historical dimension of Europeanization on Southeast Europe, a policy paper on best-practices of successful historical cases of Europeanization in Southeast Europe and a number of other dissemination and communication activities. These outputs will attract the attention of academia, policy-makers and also European society since they are a valuable source of schol
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Research training in plasma science and technology'.

assistant: **Innovation**

Research Training in Plasma Science and Technology (PLASMAST) The National Centre for Plasma Science and Technology at Dublin City University offers EU-Marie Curie Research Training Fellowships (3-12 Months) Research Training is Offered In:Optical and particle diagnostics of DC and RF low temperature plasmas;emission, absorption and laser spectroscopy of laser plasmas and electrical discharges;numerical modeling of plasmas;thin film deposition (via pulsed laser, magnetron sputtering and neutral beam systems);plasma surface modification/processing of electronic materials and industrial coatings; plasma enhanced chemistry and surface analysis Expertise and Facilities: Range of RF and DC low temperature plasma devices;Automated probe systems;Extensive suite of picoseconds, nanosecond solid state/tuneable dye lasers and OPO;Various high resolution FTIR/IR - X-ray spectrometers;Pulsed laser deposition (PLD) systems;Magnetron sputter systems with ion mass and energy analysis of deposition fluxes;Range of CCD and ICCD imaging systems; XRD, UHV-STM, AFM, LEED-Auger surface characterization. Candidates: Postgraduate students pursuing doctoral students in a country other than the Republic of Ireland. Minimum Qualification (or equivalent) Required: B.Sc. (Honours 2nd class or higher) or M.Sc. in Physics, Chemistry, and Electronic/Mechanical Engineering. Materials Science or related areas. Participation of both genders in an equal opportunity scheme is encouraged. Conditions: Nationals of an EU member state or EU associated state
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Modulation of pathways to apoptosis - reversal of a cancer phenotype' in the context of a Fourth Framework call.

assistant: **Objectives**

Research objectives and content Defects in initiation and execution of apoptosis are common in cancer. They are critical for neoplasticdevelopment and resistance to cytotoxic chemotherapy. This project investigates the reversibility of l this cancer phenotype. The host laboratory has generated tumour suseptible mice by targeted deletionof genes involved in apoptosis. Cell lines have been derived from tumours arising in these mice and partially characterised. By restoring absent components of the cell death pathway, or genes involved downstream, the effect on regulating apoptosis and response to therapy will be studied. Cell lines will be transfected with conditional expression vectors where the transfected gene is expressed in the presence of tamoxifen. The effects on apoptosis in vitro will be studied by direct examination of cells using time lapse videomicroscopy. By injecting cells into mice, the in vivo effects of conditional expression of death genes will be studied using morphometric analyses and flow cytometry. Training content (objective. benefit and expected impact) The training objectives are to gain further experience of molecular biology techniques, particularly the use of novel systems for the conditional expression of genes, and methodology used to assess apoptosis in vitro and in vivo in a major European laboratory working on apoptosis. The project seeks to examine e feasibility of replacing death genes as a strategy for the management of cancer Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Biochemical and cell biological characterization of BRX, a novel regulator of root architecture in Arabidopsis, and its role in hormone homeostasis' (BIOCELLCHARABRX) under Sixth Framework.

assistant: **Objectives**

In past years, mutagenesis approaches have proven immensely successful in dissecting the genetics of plant development. While genes that qualitatively affect plant development are very useful for understanding the mechanistic basis of growth and development, these genes appear less likely targets for the evolution of plant morphology than genes that modify the quantitative expression of a trait.Exploiting natural genetic variation enables the detection of alleles that give rise to variation observed within species, which are generally much less characterized than qualitative traits. Natural genetic variation in the model plant Arabidopsis thaliana has been touted as an untapped resource to understand plant genetics and development.The novel Arabidopsis gene, BREVIS RADIX (BRX), was identified using natural variation to isolate regulators that are responsible for intraspecific variation in root system morphology.BRX encodes a protein of unknown function and is the founding member of a small, plant-specific gene family, which is highly conserved among angiosperm species. The primary focus of the proposed research is to elucidate the biochemical, physiological, and cell biological functions of BRX.To this end, my specific aims are to:- determine the role BR X plays in coordination of auxin and brassinosteroid signalling;- understand the regulation and function of the BRX protein; and- define the cell biological and physiological effects of presence or absence of BRX activity by microarray analysis of BRX-inducible lines.The proposed research will result in the first detailed characterization of the biochemical and cell biological function of BRX, the founding member of a novel, plant-specific gene family.Moreover, the brxS mutation provides a unique tool to address how aux
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'European Nuclear Science and Applications Research' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

ENSAR is the Integrating Activity of Nuclear Scientists from almost all European countries performing research in three of the major subfields of Nuclear Physics: Nuclear Structure, Nuclear Astrophysics and Applications of Nuclear Science. It proposes an optimised ensemble of Networking (NAs), Transnational Access and Joint Research Activities (JRAs), which will ensure qualitative and quantitative improvement of the access provided by the current seven infrastructures, which are at the core of this proposal. The novel and innovative developments that will be achieved by the RTD activities will also assure state-of-the-art technology needed for the new large-scale projects.Our community of nuclear scientists profits from the diverse range of world-class research infrastructures in Europe that can supply different ion beams and energies. We have made great efforts to make the most efficient use of these facilities by developing the most advanced and novel equipment needed to pursue their excellent scientific programmes and applying state-of-the-art developments in nuclear instrumentation to other research fields and to benefit humanity (e.g. archaeology, medical imaging). Together with multidisciplinary and application-oriented research at the facilities these activities ensure a high-level socioeconomic impact.To enhance the access to these facilities, the community has defined a number of JRAs, using as main criterion scientific and technical promise. These activities deal with novel and innovative technologies to improve the operation of the facilities. In addition, a key JRA aims at integrating the laboratories in Central and South-Eastern European countries with those elsewhere in Europe.The NAs of ENSAR have been set-up with specific actions to strengthen the commun
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Management of the Communities' intellectual property rights'.

assistant: **Concept**

Specific Objectives:1. To assess and protect JRC technologies;2. To maintain, update and exploit the Communities IPR portfolio;3. To raise awareness and motivation of JRC staff on IP protection issues. Anticipated milestones and schedule 1. IPR guidelines available end February 2003 Review achieved by end April 2003 Evaluation of trademarks, patents and software;2. General support to JRC and non JRC customers is as requested and on-going;3.1. One seminar in ISPRA by June 2003;3.2. Two seminars on other sites by end 2003.Planned Deliverables:1.1 IPR internal guidelines on the handling of IPR at the JRC endorsed by the DG;1.2 List of patents to be kept / abandoned;1.3 Recommendations for exploitation;1.4 Recommendations for filing or abandon;2. IPRs filed License agreements;3. Three awareness seminars. Output Indicators and Impact Number of patents abandoned 5 trademarks, 5 software, 10 patents filed. User satisfaction 20 IPR filed by end 2003 5 licence agreements income from licensing to cover 25% of patent costs.Summary of the Action:The management of the intellectual property owned by the Communities is carried out for and on demand of all Commission services; JRC and ERAIE unit centralise all requests from client DGs in relation to IP protection. In particular it includes activities such as registration and protection of various trademarks of the Communities, keeping software creations under seal and advising clients DGs on various IP Issues.Activities will encompass:1.Development of IPR guidelines for JRC researchers Review the last third of Community portfolio patents not reviewed in 2002;2. On going evaluation of marks, patents and software submitted;3. General support to JRC and non JRC customers, including: - Support to JRC staff in writing consortium agreements
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Cell-instructive matrices to deconstruct tumour tissues', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

This research addresses a clinical problem with an innovative approach. Pancreatic cancer is one of the deadliest cancers and only 10% of patients survive 5 years after diagnosis. To find better therapies, we need patient-specific models that mimic the biology of tumour tissues and target interactions between different cell types. We will develop a controllable platform for modelling the human disease in the laboratory. We will use our new platform to discover better ways of treating the disease.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Energy Harvesting Networks - Resource Allocation and Performance Evaluation'.

assistant: **Objectives**

The project will focus on the design and performance evaluation of algorithms for networks of energy harvesting wireless nodes. Recent advances in the areas of energy harvesting and ultra-low-power wireless communications will soon enable the realization of such networks. They will find applications in healthcare, manufacturing, public safety, and will serve as building blocks for the Internet of Things and Cyber Physical Systems. In a recent interdisciplinary project, the PI (with other co-PIs) developed prototypes of Energy Harvesting Active Networked Tags (EnHANTs – http://enhants.ee.columbia.edu ). Building on the success of EnHANTs, we will consider the theoretical design challenges related to wireless networking. We will focus on the design and performance evaluation of resource allocation and Medium Access Control (MAC) algorithms for wireless networks composed of energy harvesting nodes. The algorithms will take into account cross-layer considerations and will deal with various functionalities, including flow control, topology control, and routing and with various environment and technological constraints.The PI will visit Tel Aviv University (Israel), and hence, an important component of the project is transfer of knowledge to the European research community from Columbia University and the EnHANTs project. The project will expose European researchers and students to new problems, provide them access to the U.S. research infrastructure, and allow them to establish long-term collaborations with researchers in Columbia. We believe that the research and knowledge transfer activities will make an impact on the areas of Cyber-physical systems and Internet of Things, and will contribute to the European competitiveness in these emerging areas.Finally, an important com
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Enabling Grids for E-sciencE-II', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

EGEE-II will build on the work of the EGEE project to provide a production quality, seamless Grid infrastructure service across the ERA and across the globe. The EGEE infrastructure benefits academic and industrial researchers in their daily work by simultaneously supporting many applications from diverse domains. EGEE-II will spread knowledge about the Grid and its benefits to researchers and students in High Energy Physics, Biomedicine, Earth Sciences, Astrophysics, Computational Chemistry, Fusion and other fields, through dedicated support teams and a well-defined training programme, as well as reinforcing links with the full spectrum of interested industrial partners. EGEE-II will manage, extend and consolidate the infrastructure, to link national, regional and thematic Grid efforts and provide interoperability with other Grids, establishing a world-wide Grid infrastructure. Built on the pan-European research network GEANT2, the EGEE Grid provides researchers with round-the-clock access to a common pool of major storage, compute and networking facilities, independent of geographic location. The resulting high capacity infrastructure greatly surpasses the capabilities of local clusters and individual centres, providing a unique tool for collaborative compute-intensive science (e-Science).  User specific services from other projects and sources will be integrated in EGEE-II's existing open source middleware to further increase the functionality, security and ease-of-use.As the European flagship RI Grid project, EGEE-II will have a structuring effect through its role as a coordination body for related Grid projects, reducing the digital divide across European states and actively participating in developing Grid standards. EGEE-II will pave the way for a long-term susta
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Vehicles and VRU Virtual eValuation of Road Safety' (V4SAFETY) under Horizon Europe.

assistant: **Objectives**

In order to set policies for road safety in the coming decades and push for Vision Zero, an accepted and reliable method for the comparison of safety measures for CCAM is needed. The proposed method will deal with the safety of all road users, from vulnerable road users to vehicle occupants.  V4Safety will provide a prospective safety assessment framework that can handle a large variety of safety measures, ranging from in-vehicle safety technology, new vehicle types, infrastructure solutions to regulations that influence road user behaviour. It includes methods to project the results in future scenarios and over EU regions for use by policy makers, authorities and consumer organizations.V4Safety strives for comparability of results of safety studies by not only providing the framework but also guidelines for using it. The guidelines show how to select, configure and connect relevant human, vehicle and environment models; how to select a baseline approach and how to project to a conclusion to different regions of interest in the EU. Moreover, the framework will also allow projections for future scenarios, incorporating possible changes in the mobility system.To understand differences between studies and to understand the influence of underlying data, assumptions and models, the method provides tools to characterise the influence of the determinants.Combined with a well-defined baseline approach – what to compare to? - the resulting transparency and consistency in simulation-based safety assessment leads to much improved comparability and reliability of assessment conclusions.


**Keywords:** safety, prospective, assessment, framework, measures, policy, authorities, type approval