RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Wearable Hybrid Interfaces of Smart Printable Engineered Responsive nanomaterials enabling real-time cfDNA sensing for early diagnosis' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Cancer leaves tiny fragments of genetic material, called circulating cell-free DNA (cfDNA), in the blood. Detecting these fragments can help doctors spot cancer earlier, track treatment, and monitor relapse. Today, tests for cfDNA rely on lab-heavy methods like PCR or sequencing, which are slow, expensive, and unsuitable for regular monitoring. The WHISPER (Wearable Hybrid Interfaces of Smart Printable Engineered Responsive nanomaterials enabling real-time cfDNA sensing for early diagnosis) project aims to change this by creating a wearable patch that can track cancer-related cfDNA in real time, directly on the body. This device combines smart nanomaterials that selectively capture cfDNA, tiny electrochemical sensors that turn this binding into an electronic signal, and flexible, printable electronics for comfortable skin wear. Unlike current tests, WHISPER works without complex equipment or sample processing, offering a continuous, low-cost, and patient-friendly alternative. By making cancer monitoring as simple as wearing a patch, WHISPER could transform early diagnosis and personalized treatment, while also advancing Europe’s goals in precision medicine and digital health.


**Keywords:** Circulating cell-free DNA (cfDNA), Wearable biosensors, Electrochemical nanomaterials, Real-time cancer monitoring, Printable flexible electronics, Personalized treatment
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Collision-free Design of Rational Single-loop Linkages', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

This project focuses on the collision-free design of single-loop mechanisms, which are customized devices synthesized for a given task. With only few degrees of freedom, such mechanisms can perform very complex spatial motions, which nowadays industrial solutions can achieve for an extensive energy cost or cannot achieve at all. Although the kinematics of the single-loop mechanisms is a well-investigated topic among mechanism scientists, there exist very few real-world applications, because the synthesized kinematic models do not consider collisions between the links and joints. Also, their structural design is complicated – engineering tools struggle when dealing with closed-chain mechanisms given algebraically due to numerical rounding. The project aims to solve this problem through recent progress on mechanisms constructed by rational motion factorization along with numerical optimization methods. Rational motion has, in addition to the possibility of factorization, other benefits such as motion parametrization, algebraic collision detection, or can approximate even other types of motions, making the output of this work widely adaptable. This project will provide a simplified mechanism collision model, quantify the collision states on a continuous level, optimize the rigid body structural design, and deal with special cases such as folded states of mechanisms. Daniel Huczala recently finished dissertation at VSB-TU of Ostrava, Czech Republic, where he dealt with the synthesis of serial kinematic structures of robotic manipulators. His obtained knowledge in optimization of mechanisms design will be joined with the theoretical kinematics expertise of researchers at the Unit of Geometry and Surveying, University of Innsbruck, Austria, who participated in the development
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Supersolids and Beyond: Exploring New States of Matter with Laser-Cooled Dipolar Molecules' in the context of a Horizon 2020 call.

assistant: **Objectives**

Quantum mechanics becomes most fascinating when its counterintuitive phenomena are observable on a macroscopic scale. The goal of this project is to realize and study novel states of matter that are paradigmatic examples of such behaviour.My primary focus is the paradoxical supersolid state of matter, which combines the crystal structure of a solid with the frictionless flow of a superfluid. The very existence of this state has been debated intensively for over 60 years. After decades of inconclusive efforts in helium, I have recently observed evidence for this state in magnetic quantum gases. This discovery has raised a plethora of new questions, which can be addressed with neither magnetic atoms nor helium, and thus require fundamentally new experimental approaches.In this project I will use laser-cooled dipolar molecules to explore supersolidity far beyond the state of the art. Starting from an ultracold gas of molecules, I will study - from few to many-body - long-discussed scenarios for supersolidity. The use of flexible optical potentials will allow me to investigate the role of doping, defects, dimensionality and disorder on the formation and dynamics of a supersolid. By using high-resolution, single-molecule imaging, I will be able to follow the corresponding dynamics down to the most elementary level, where correlations and entanglement become accessible.A particular significant generalization of this scenario arises when the spatial ordering competes with magnetic ordering. The molecules employed exhibit both electric and magnetic dipole moments and thus naturally feature the additional degree of freedom required to realize spin models. This will enable studying further exotic states of matter in which topological effects are expected to emerge.The extraordina
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Transient Analysis of Exotic Materials for Electromagnetics' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Simulating the interaction of electromagnetic interaction  plays a centrol role in the design of new, exotic materials for use in electronic, photonic, and optical systems. In order to design these systems subject to all technical and economic constraints, broad band information on their behaviour is indispensable. Moreover, modern exotic materials and the devices in which they are used can exhibit nonlinear behaviour. This leaves transient (i.e. time domain) simulation the only viable option.The aim of this project is the development of a design methodology and the corresponding software tools for the exotic electromagnetic materials for use in photonics, transformation optics, biomedical imaging, and nano-technology.This project is innovative because it will enable for the first time (i) the design of nonlinear exotic electromagnetic materials, (ii) the design of devices comprising both regions containing uniform and regions containing non-uniform exotic materials, (iii) the design of exotic materials of size and complexity as encountered in practical situations, and (iv) the deployment during the design process of computing infrastructure that is heterogenous and unreliable, allowing the use of more affordable hardware and leading to true scalability.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Multicore Analysis Service and Tools for Embedded Critical Systems' (MASTECS).

assistant: **Innovation**

MASTECS will bring to the market innovative and exploitable technology for multicore processor timing analysis (MTA). It will be used by critical embedded software industries (focusing on automotive and avionics) to support advanced software functions (such as autonomous driving) which are competitive factors in every new product. MASTECS will enable these industries to exploit increased computing performance from multicore platforms allowing new functionally-rich critical and performance-demanding software, leading to reduced fatalities in the road, safer and cheaper air travel and reducing CO2 profile of planes and cars.MASTECS builds on TRL6 MTA technology developed by its partners and currently being used in several commercial pilot studies by aerospace and automotive tier-1 suppliers. MASTECS will bring it to TRL8, addressing automation, certification, and qualification requirements.The innovative inter-disciplinary MASTECS approach combines the hardware (multicore) expertise (BSC), software timing expertise (RPT), and end-user expertise in terms of requirements and certification (MM and UTRC). This award-winning technology will be commercialized to open a new market in which MASTECS will provide a highly competitive solution by focusing on process, automation and certification support to meet the needs of the safety critical industry.MASTECS implements a solid dissemination and communication approach that ensures the offered product reaches its targeted industrial audience. MASTECS will launch a combined product/service offering for the aerospace and automotive markets, significantly reducing the time-to-market of their systems. The project will boost MTA technology for market take-up within 2 years of project start. Benefiting from first-to-market positioning hel
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Pathophysiology of rare diseases due to ciliary dysfunction: nephronophthisis, Oral-facial-digital type 1 and Bardet-Biedl syndromes' under Seventh Framework.

assistant: **Concept**

Primary cilia have been recognized on nearly all-mammalian cells. Emerging data suggest that they act as cellular antennae with diverse motility and sensory functions, detecting a wide variety of signals. As such, defects in cilia formation or function have profound effects on the development of body pattern and the physiology of multiple organ systems. Ciliary defects underlie a wide range of human disorders, including the rare and heritable Bardet-Biedl (BBS), Oro-facial-digital type 1 (OFD1) and nephronophthisis (NPHP) syndromes. Each of these disorders present with defining features but all are characterized by polycystic renal disease. The proteins encoded by the genes responsible for these disorders, as well as those implicated in heritable forms of cystic kidneys, are all located to the cilium/basal body/centrosome complex, suggesting that ciliary dysfunction might be the unifying pathogenic concept underlying cystic kidney disease. However, the molecular mechanisms remain undetermined. We propose to use BBS, OFD1 and NPHP syndromes as model systems to study the physiological role of primary cilia, with special emphasis on their role in the genitourinary tract and in the development of renal cysts. The experimental plan proposes to generate and make available to the scientific community in vitro and in vivo models to study the physiological role of primary cilia and of OFD1, BBS and NPHP proteins in the formation and function of the primary cilium. These tools will allow the analysis of the ciliary protein interaction network and of the downstream pathway in the absence of BBS, OFD1, or NPHP. Finally, we propose to identify and evaluate potential therapeutic agents. The biological relevance and significance of the results obtained will have implications far beyon
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Spectroscopy of free and bound baryon resonances in pion-induced reactions' to be submitted under Fourth Framework.

assistant: **Abstract**

Research objectives and content A major goal of the current research programme is to identify effect of the chiral simmetry restoration. While broken for strongly interacting free particles, chiral simmetry is predicted to be restored with increasing nuclear density and temperature, resulting in a change of the hadron masses as compared to their free values. It is proposed to perfom Ames spectroscopy of the free and bound N(1535) nucleon resonance following pion-induced reactions on targets of liquid hydrogen as well as on solid targets of complex nuclei exploiting the secondary high-momentum pion beams available at pion beam facility of GSI Darmstadt. Mass reductions of about 20% can be expected. The n meson is identified via an invariant mass analysis of the two decay photons corresponding to the 40% decay channel of the meson. The photons are observed in a large modularized two-arm photon spectrometer which represents one of the main experimental tool to be t in the proposed experiments. Two tasks have to be perfomed before the actual measurements. One is the careful study of the experimental arrangement using extended computer simulations. Here the response of the detectors to the two photon decay of the , signal is taken i account and the effects of electronic triggers that have to be implemented are investigated in order to enhance the n sign against the background of unwanted reactions on the event level. These studies will require the first 5 months of the proje The second task is to install the TAPS photon spectrometer in its optimized geometry at the pion beam line. Commissioni runs of the pion beam are required in this place as well as tests of the new TAPS electronics which is now under developn by the collaboration. The result will be a complete description
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Negotiated environmental agreements: policy lessons to be learned from a comparative case study' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

This research will focus on the use of negotiated agreements as a policy instrument to deal with environmental problems It is the main goal of this proposal to push the analysis on negotiated agreements, as defined above, further in a co-ordinated and multi-disciplinary way. On the one hand through the enhancement of the theoretical framework with regard to negotiated agreements and on the other hand through the evaluation of existing negotiated agreements based on a confrontation between theory and empirical assessments. This, in order to set out policy options that will be extrapolated out of this research. These policy options will take into consideration the Community Framework that is in the process of being elaborated by DG XI. The purpose of these policy options is to add value to the Community Framework and to serve as a guideline for countries in the process of integrating negotiated agreements in their set of environmental policy instruments. The central question of this research proposal is: Which specific characteristics of negotiated agreements and which factors within the institutional-economic context wherein a negotiated agreement is used influence the performance of negotiated agreements? The research design of this proposal consists of three elements, namely a theoretical analysis, an empirical analysis and an elaboration of policy options and a checklist. The purpose of splitting up the research design in a theoretical and empirical stage is to have an intense confrontation between theory and practice in order to test whether the theoretical assumptions are correct and to test the relevancy of these assumptions for the actual practice. The theoretical analysis will be executed in a multi-disciplinary way building for the most part on existing literatu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'ATTOsecond Photochemistry: controlling chemical reactions with electrons', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

ATTOP is a theoretical chemistry project that will explore the synergy between the two fields of attoscience and photochemistry. Chemical processes initiated by light are extremely widespread and their applications cover vital molecular research fields from medicine to computer science and energy conversion. However, photochemical reactions are limited by the nature and finite number of molecular electronic excited states. To overcome this fundamental limitation, ATTOP proposes to bring very recent technological progress in extreme ultrashort light pulses - attosecond science - to the field of photochemistry and to launch the unprecedented field of ""atto-photochemistry"". Indeed, light pulses of such short duration have a large spectral bandwidth and excite multiple electronic excited states in a simultaneous and coherent manner. This superposition, called an ""electronic wavepacket"", has a new electronic distribution and is thus expected to lead to a new reactivity. The following questions remain for now unresolved: what would be the reactivity of a molecule in these new types of electronic states that are becoming accessible experimentally? To what extent will the manipulation of an electronic wavepacket produced by an attosecond domain pulse transform the outcome of chemical reactions? As an emerging field, atto-photochemistry requires theoretical support right from the start. Thanks to the PI's unique combination of expertise in both theoretical attoscience and photochemistry, the ATTOP team will describe accurately chemical reactions induced by electronic wavepackets via attosecond domain pulses. The final aim of ATTOP is to develop a general know-how to design molecular systems, electronic wavepackets and attosecond experiments that transform the outcome of phot
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Investments in the electricity market: Model and Applications' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

* Research Objective Many economists are concerned that without regulation, insufficient generation capacity will be built in the liberalized electricity market, given its market failures: markets are incomplete and generators have market power.  The aim of this project is to study (1) whether government intervention is required to regulate the security of supply and, if so, (2) what the best regulatory scheme would be. As market power has been studied extensively, we will assume that markets are competitive, but incomplete.  * Research methodology 1. We develop a long-run stochastic partial equilibrium model of the electricity market under perfect competition, with risk-averse firms and incomplete forward markets. The model includes production, spot market sales, contracting and investment decisions. The model is expected to show that the lack of a complete set of forward markets leads to underinvestment.  2. We extend the model to include a welfare-maximizing regulator. This regulator has two instruments: (a) it can regulate the risk taking by firms using a ‘capital adequacy regulation’, (b) it can buy peak-load power plants to provide backup power during emergencies fulfilling the role of ‘lender-of-last-resort. The model will determine which regulation is socially beneficial.   * Training and Impact  This fellowship will allow the researcher to join well-established European researchers to advance the state of the art on regulating investments in network industries. The project will contribute to Europe’s secure energy supply and to the establishment of the fellow as an independent researcher.