RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'A disruptive information system for SMEs’ business consulting using problem solving techniques, semantic technologies and social media' under Horizon 2020.

assistant: **Concept**

The DOMINOS objective is to propose in the market a disruptive information system for SMEs’ business consulting using problem solving techniques, semantic technologies and social media. It will be a completely new and innovative service in terms of service offering (features and delivery) and business model. DOMINOS will be accessible by companies through the Web, helping them in the decision-making processes related to business issues by allowing users to access: - Structured methodologies to business problem solving, suggesting innovative solutions, making use of the power of long acknowledged evolution paths of technological and industrial processes, which stem from TRIZ theory;- External expertise offered by knowledge markets and the DOMINOS collaborative environment;- Access to relevant information for SMEs business management decisions through semantic technologies;DOMINOS will support SMEs in both taking business management choices based on more informed decisions, as well as in interacting with external advices coming either from knowledge markets (communities), or through specific questions / problems asked to consultants that will interact through DOMINOS. The business model will be completely new for the management consulting business, not relying on hourly-based consulting fees, but offering an on-line Freemium service (free service for basic functions, premium service for advanced ones), allowing SMEs to choose if, when, and on which specific topic make use of consultants. SMEs, thus, will be able to connect with experts in existing knowledge markets as well as consultants, with the possibility to establish long term relationships to ensure sustainability of the proposed solutions (no “hit and run” approach from consultants) at a fair price.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'First principles design for damage resistance against capsize' in the context of a Fifth Framework call.

assistant: **Objectives**

Unlike many other aspects of RoRo vessels design, which have undergone continuous progress towards new technologies, safety still lags behind. Traditionally handled with strict compliance to rules and regulations, the survivability of this type of vessels to damage at sea has proven dramatically insufficient. The goal of this project is to develop and validate by demonstration, an innovative design methodology based on risk assessment approach which employs first principles models representative of the physics involved in the flooding process. This tool will allow practising naval architects to realistically predict, measure and improve the level of safety of a given RoRo design and therefore it will allow total integration of survivability in the design process as a regular design parameter.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Improving Life expectancy of LUNG transplant recipients through innovative ex vivo perfusion gene therapy' in the context of a Horizon Europe call.

assistant: **Objectives**

Patient survival after lung transplantation (LTx) for end-stage pulmonary disease is poor (5-year survival rate of 59%) due to ischemia reperfusion injury (IRI) and graft rejection. No therapies are available to prevent IRI, and current immunosuppression causes toxicity and morbidity. Novel strategies are required that can mask the graft from the recipient’s immune systemThe LifeLUNG initiative unites the critical building blocks available in Europe to advance towards a novel paradigm for LTx. Ex vivo lung perfusion (EVLP) is a clinically used platform to maintain active lung physiology outside the body, making pre-LTx organ engineering a reality. The project aims to advancing EVLP technology to enhance our understanding of transplant rejection through accessible models. By utilizing biobanks of lung biopsies from both clinical LTx cases and established animal models of IRI and rejection, LifeLUNG will apply advanced machine learning and AI-driven deep sequencing to identify key immune factors and gene targets. The latter will be targeted in LifeLUNG with gene therapeutic agents (GTAs) that can be delivered during EVLP to selectively modulate immune responses. Several delivery tools including adeno-associated viral vectors, virus-like particles and lipid nanoparticles, will be tailored to ensure precise and graft-specific gene modulation, enhancing the therapeutic potential for reducing IRI and preventing rejection.  Also the efficient production strategies of these GTAs will be an integral part of LifeLUNG. In parallel, LifeLUNG will explore the economic and ethical paradigms of genetic modification of lung transplantation and reflect its implementation into the broader research and clinical framework. The interdisciplinary nature of LifeLUNG will support the training
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Big Energy Data Value Creation within SYNergetic enERGY-as-a-service Applications through trusted multi-party data sharing over an AI big data analytics marketplace'.

assistant: **Concept**

The transition to the smart grid era is associated with the creation of a meshed network of data contributors that necessitates for the transformation of the traditional top-down business model, where power system optimization relied on centralized decisions based on data silos preserved by stakeholders, to a more horizontal one in which optimization decisions are based on interconnected data assets and collective intelligence. Consequently, the need for “end-to-end” coordination between the electricity stakeholders, not only in business terms but also in exchanging information is becoming a necessity to enable the enhancement of electricity networks’ stability and resilience, while satisfying individual business process optimization targets of all stakeholders involved in the value chain. SYNERGY introduces a novel reference big data architecture and platform that leverages data, primary or secondarily related to the electricity domain, coming from diverse sources (APIs, historical data, statistics, sensors/ IoT, weather, energy markets and various other open data sources) to help electricity stakeholders to simultaneously enhance their data reach, improve their internal intelligence on electricity-related optimization functions, while getting involved in novel data (intelligence) sharing/trading models, in order to shift individual decision-making at a collective intelligence level.To this end SYNERGY will develop a highly effective a Big Energy Data Platform and AI Analytics Marketplace, accompanied by big data-enabled applications for the totality of electricity value chain stakeholders (altogether integrated in the SYNERGY Big Data-driven EaaS Framework). SYNERGY will be validated in 5 large-scale demonstrators, in Greece, Spain, Austria, Finland and Croatia involv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Abelianisation of Connections, Quantum Curves, and Spectral Clusters' (AbQuantumSpec) targeting Horizon 2020.

assistant: **Abstract**

This cross-disciplinary project lies at the interface of geometry, mathematical physics, perturbation theory, and integrable systems, combining techniques from algebraic topology, cluster algebras, ordinary differential equations, and asymptotic analysis. The main goal is to advance our understanding of the geometry of character varieties and their quantisation. This project -- carried out by Nikita Nikolaev under the supervision of Marta Mazzocco at the University of Birmingham -- is expected to result in a fundamental innovation in geometry and have important implications for quantum field theory. It will open a vast new scientific arena and will serve to establish Nikolaev amongst research leaders in this highly active research area.  Character varieties are geometric spaces which are ubiquitous in mathematics and physics, where they capture important topological and quantum invariants. These spaces parameterise singular complex ordinary differential equations (such as the Airy and Bessel equations, or even time-independent Schrödinger equations), as well as their generalisations: meromorphic connections on vector bundles over a Riemann surface. However, character varieties are usually complicated singular spaces, so the valuable information they encode is not easy to access. This project will develop a new method to describe character varieties called abelianisation. Ideas behind abelianisation stem from the WKB method in quantum mechanics and have recently resurfaced in the context of quantum field theory and string theory. Abelianisation will allow to construct special coordinate systems on character varieties (called spectral coordinates) which naturally capture crucially important geometric structure of character varieties (most prominently the symplectic and cl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Computer aided reduction of seismic risk with application in existing cities, town planning and construction' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

The objective of the proposed project is to develop an integrated methodology tailored around a knowledge based software package that will support seismic risk mitigation decisions for a town (e.g. selective retrofitting of existing structures, monuments etc.) and for its future expansions (new construction: where and how), in order to optimize the planning process from a social and economic viewpoint. The innovation of the project will be in its extensive utilisation, development and integration of state-of-the-art information processing tools that will yield more reliable and easier to use loss estimates.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Conference on potential impact of new technologies on neonatal vaccination" (NTNV)"' (NTNV).

assistant: **Concept**

The Conference on Potential impact of new technologies on neonatal vaccination" will be organised under the supervision cuff EC-US Task Force on Biotechnology Research, and will be held in Siena (Italy) at the Campus of Chiron Spa from 6 to/11/2001.A Scientific Co-ordinator will take the overall responsibility for the scientific organization of the meeting together with two Scientific Committees, which will be composed of the most prominent EC-US scientists involved in this field. At the endow the event the Co-ordinator flanked by both the EU and the US Scientific Committees will produce a document on the Conference results which will summarise all the activities performed during the event and all the relevant conclusions. The Co-ordinator will prepare for the Commission, as a final result of the Conference, a dissemination plan to be also employed in developing Countries."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Support ceec scientists to participate in a 10-days high level meeting on how crystallography might contribute to proceed from structural genomics to drug design' (DRUGDESIGNFROMGENES) under Fifth Framework.

assistant: **Objectives**

Research on sequencing the human genome and those of pathogenesis organisms provide information which promise developments in the drug discovery process. The purpose of the meeting is to assemble the achievements of structure-based drug design and to review future prospective. By discussing real life examples, the underlying principles, strengths and weaknesses of the approach will be argued, from protein structures to emerging techniques (bio computation, combinatorial chemistry, high throughput screening), from advances in structural methods (X-ray and cry-electron diffraction, synchrotron radiation, NMR & mass spectrometry, modelling) to structure prediction (threading sequences , evolution, fold assignment) ; a strong accent will be put on the synergistic use of each of them in order to prospect an efficient drug design .
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Colour and Kinematics of Quarks and Gluons inside Loops' under Horizon 2020.

assistant: **Concept**

The LHC era of fundamental physics presents a formidable challenge for theorists - the precision of Standard Model predictions should be improved by a factor of two. One of the major bottlenecks is the availability of two-loop scattering amplitudes in quantum chromodynamics (QCD), which is largely limited to 2 -> 2 processes due to the daunting complexity of the perturbative series. The need for amplitudes of higher-multiplicity processes calls for new analytic insights into the intricate structure of gauge theories.This project centers around one such insight - colour-kinematics duality - and aims to convert it into a powerful ally for future QCD calculations. This will be possible because the duality, recently generalised from the purely gluonic sector to full QCD, contains valuable information about non-Abelian gauge theories. In particular, it relates aspects of QCD calculations that are simpler to aspects, which are thought to be much harder. This input non-trivially constrains the S-matrix and thus can be used to reduce the number of subcalculations needed. To achieve this, we plan to pursue the four following lines of research:- systematise the relations among generalised unitarity cuts, which follow from tree-level amplitude relations induced by the duality of colour and kinematics;- simplify the analytic structure of loop integrands via smart loop momentum parametrisation;- develop tools for tree-level amplitudes in six-dimensional gauge theories, which serve as input for dimensionally-regulated two-loop amplitudes in four dimensions;- calculate previously inaccessible two-loop amplitudes contributing to NNLO corrections to 2 -> 3 QCD processes at the LHC.This will improve our understanding of gauge theories and open the way to previously intractable calculatio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Real-time Multiscale Imaging of Pathological Calcification - Zooming in on Aortic Valve Calcification' (REVALVE).

assistant: **Innovation**

Calcifying Aortic Valve Disease (CAVD) is a cellular-driven disease that actively alters the structure and composition of the valve extracellular matrix, leading to severe disfunction of the heart. Because the molecular mechanisms underlying CAVD are still unknown, there are currently no drug-based therapies and valve replacement is the only available treatment.Specifically, it is still unknown (1) how the disease modifies the extracellular matrix (ECM) to become susceptible for mineralization, (2) how cell differentiation and matrix modification lead to calcification, and (3) how the mineral develops within the matrix. We lack these answers mainly due to our inability to characterize matrix development with the required chemical and structural details during the CAVD process. I aim to push our capability for in situ imaging of ongoing biological matrix formation processes from the micron to the nanometer scale by creating a designer tissue imaging platform for CAVD. This will be achieved by: •creating a human CAVD-on-a-chip that allows the application of mechanical and (bio)chemical cues to accurately emulate the early stages of CAVD;•designing the chip to accommodate a 3D correlative multiscale imaging and spectroscopy workflow to study matrix modification and mineralization in the native state from the micrometer to the nanometer scale; •developing a method to (1) collect cryo-sections from the ECM created at precisely selected points in space and time, to (2) transfer these to a transmission electron microscope and (3) revive -inside the microscope- the biological processes that are ongoing in the at the moment of cryo-arrest. This will allow for the first-ever dynamic nanoscale imaging of ongoing ECM processes.These new capabilities will allow breakthroughs in unde
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'IPR-Helpdesk' (IPR-HD).

assistant: **Concept**

Intellectual Property (IP) is the driving force behind innovation in the technological market. Without the rights that govern the marketable potential of innovation, the commercial value of such products proves little incentive for stakeholders. However, stakeholders need to know the tools with which to protect knowledge as well as how to exploit it. In a market where the 'open innovation approach' is the norm, SMEs especially must be given assistance to compete with larger organisations when RTD activities are limited through a lack of funding, expertise, etc. By commercially exploiting knowledge SMEs can meet the challenges of their larger competitors.The use of networks is also widely acknowledged as a mechanism for triggering Innovation, and this 'cluster' approach is particularly beneficial to associate new EU Member States still initiating the process of innovative design. The IPR-Helpdesk aims to be a key player by providing first-line assistance to those seeking guidance in IPR issues. The main focus will be to provide stakeholders already participating or seeking to participate in EU-funded initiatives in fundamental issues such as knowledge transfer and protection, and also in the commercial exploitation of that knowledge.Key points:- SMEs are the main target audience for the project, and for this reason all the services are geared towards providing information accessible for non legal experts.- The Helpline is the primary tool of assistance, answering queries and assisting the Consortium with the information needed to develop the rest of the services, mainly the content of the website. Helpline and Info-service (web) will be offered in 6 languages.- The dissemination policy will focus on raising awareness of the services. Training actions are only foreseen fo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'CoopClickCat', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The CoopClickCat project features Cooperatively operating Click-derived ruthenium Catalysts for the efficient oxidation of organic and inorganic substrates with high rates and turnover numbers. For this purpose, triazolylidene ligands, which are readily available through click-chemistry, will be functionalized with a cooperative donor site for improving the catalytic activity of the bound ruthenium center. The ligand design involves a sterically constraint position of the donor site, thus preventing this group from coordination to the metal center. The availability of a Lewis acid (ruthenium center) and base in a confined arrangement will enable the two sites to act cooperatively, thus providing access to concerted proton and electron transfer processes. This synergistic behavior lowers activation barriers and hence leads to a smoother potential energy surface for reduction and oxidation reactions. This unique arrangement will lead to new oxidative coupling processes and reduction pathways for the activation of abundant starting materials such as alcohols and amines, and eventually also water to reach unprecedented activity in ruthenium-catalyzed water oxidation catalysis. This project efficiently combines expertise of the researcher (Dr. Marta Valencia; hydride chemistry, alcohol oxidation) with core competences of the host lab (Professor Martin Albrecht, University College Dublin; triazolylidene chemistry, water oxidation).


**Keywords:** click-chemistry, mesoionic carbenes, ligand cooperativity, alcohol deshidrogenation, amine deshidrogenation, water oxidation