RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Charge breeding -charge breeding of intense radioactive beams' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

Description:Objectives:The development of an efficient charge breeding scheme for Radioactive Ion Beam will have a strong impact on the post accelerators planned at European large scale facilities. At ISOLDE/CERN there will be the unique possibility to carry out experiments with the two possible charge breeding set-ups with a large variety of radioactive isotopes. One charge breeding set-up is the Penning trap-EBIS combination which feeds the REX-ISOLDE linear accelerator and which has bred radioactive ions for the first time to A/q < 4.5. Cooled and bunched beams of radioactive isotopes from REXTRAP have been injected into REXEBIS and the charge states have been analysed with the achromatic mass separator. The second charge breeder is the ECRIS PHOENIX developed at the ISN ion source laboratory at Grenoble.This ECRIS is under investigation with a 14 GHz amplifier. Comparisons to measurements with the MINIMAFIOS source show higher efficiencies and shorter breeding times. The experiments are accompanied by theoretical studies with computer simulations. A second PHOENIX ECRIS is installed at the Daresbury Laboratory for charge breeding test measurements, which prepare the final set-up and experiments with radioactive ions at ISOLDE in 2002. The final goals are the comparison of breeding efficiencies and loss measurements with radioactive ions with simulation calculations and with results from the Penning trap-EBIS charge breeder.Results:Project Manager:Dietrich Habs, Sektion Physik, Am Coulombwall 1, Garching 85748, GermanyTel: +49-89-28914077Fax: +49-89-28914072E-Mail: dieter.habs@physik.uni-muenchen.deA new ECR ion source (PHOENIX) at ISN Grenoble has been developed and characterized on a test bench;- A second PHOENIX ECRIS has been acquired and purchased by Daresbury L
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The Mediterranean in the Age of Globalisation. A migration interpretation' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

This research project is grounded on previous work carried out by the candidate on economic globalisation and the sociology of migration in Southern Europe, Morocco and Albania. The aim of the project is to investigate, via field research, the dynamics of globalisation and migration with particular reference to the Mediterranean region. To do so the work will be divided into two main sections: the analysis of two case studies in border cities of Morocco and Albania, already built as work already in progress, and the analysis of a third case study, Istanbul. Afterwards an integrated approach of to both sets of analysis will be considered in order to identify the main criteria for examining the role of border cities in the Western Mediterranean region.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Reinforcing cooperation with Eastern Partnership countries on bridging the gap between research and innovation for inclusive and secure societies' in the context of a Seventh Framework call.

assistant: **Objectives**

The overall aim of the SECURE-R2I project is to reinforce cooperation with Eastern Partnership Countries (EPC) on bridging the gap between research and innovation for Horizon 2020 Societal Challenge 6. “Inclusive, Innovative and Secure Societies”. The research domains encompassed by “Inclusive, Innovative and Secure Societies” are broad. From the perspective of FP7 thematic priorities, they include ICT; Security; Nanosciences, Nanotechnologies, Materials (NMP); and Social Sciences and Humanities (SSH). These research domains also form the basis of important economic sectors in the EPC, with many potential benefits for the EU, but which also need European support to increase their exploitation. Addressing this issue, the SECURE-R2I project will assist R&D and innovation (RDI) organisations in EPC via a range of knowledge and technology transfer activities with the support of European specialists. The activities include:• Networking between EPC organisations involved in RDI for Societal Challenge 6: It consists in mapping EPC RDI organisations and organising brokerage events to stimulate cooperation;• Analysing the tech transfer opportunities and bottlenecks of EPC organisations involved in RDI for Societal Challenge 6: It consists in surveying these organisations and holding discussions with representatives of government, industry, government and intermediary bodies;• Exchanging best practices in knowledge/technology transfer via a range of specific training courses and intensive summer schools in Europe;• Twinning via R2I pilot projects: Each EPC research partner in the consortium will twin with another consortium partner who will support them to implement a bilateral R2I pilot project;• Providing innovation support services to selected, high-potential EPC (and European
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Coordination Action in support of the implementation of a Joint Programming Initiative for Combating Neurodegenerative Diseases, in particular Alzheimer’s disease' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The objective of the Coordination Action JUMPAHEAD is to support the implementation of the pilot Joint Programming Initiative on combating neurodegenerative diseases, in particular Alzheimer’s disease (JPND).Neurodegenerative disorders are incurable and debilitating conditions that result in progressive degeneration or death of nerve cells. Of these, the dementias are responsible for the greatest burden of disease, and today in Europe over 7 million people suffer from Alzheimer's disease and related disorders, with this figure expected to double by 2020 as the European population ages.Although our understanding of the mechanisms of neurodegenerative disease has greatly improved over the past few years, there is no effective treatment able to stop or even slow down the deterioration of brain functions associated with these disorders.To tackle this pan-European health and societal challenge more effectively, 22 EU countries have launched the JPND. This is an innovative programme based on a common vision to improve the impact of their combined research effort to accelerate progress towards new treatments, identify preventative strategies, and improve patient care.JUMPAHEAD will build the foundations for this initiative by supporting the development and implementation of a Strategic Research Agenda, as well as its dissemination and evaluation. This will be achieved under the direction of the JPND Management Board.The output of JUMPAHEAD over its 36 month duration will include innovative ways of pooling national expertise and resources and the establishment of closer and robust research collaborations among the participating States in the field of neuro-degeneration research. JUMPAHEAD will contribute to the European Research Area by addressing fragmentation and improving in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Molecular approach to the study of antibiotic susceptibility of Neisseria meningitidis and of its impact on pathogenesis of meningococcal infection', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

Neisseria meningitidis is a leading cause of meningitis and septicemia worldwide, associated with a high mortality rate. Since the increasing number of culture negative cases has been observed, and an immediate initiation of proper antibiotic therapy is crucial for favourable outcomes, there is an urgent need to develop rapid and specific non-culture methods of predicting of meningococcal susceptibility to penicillin. Although penicillin remains the drug of choice in the treatment of invasive meningococcal disease (IMD), since the 1980s an increasing number of meningococci with reduced susceptibility to penicillin has emerged worldwide.This phenotype is thought to be due to an alteration of penicillin binding proteins, involved in the late stages of peptidoglycan (PG) biosynthesis. Therefore the aim of this project is to develop molecular tools to predict the susceptibility of N. meningitidis to antibiotics and a pathophysiological analysis of the effects of altered meningococcal susceptibility to penicillin on virulence of the strain. This project will use a multidisciplinary approach applying bacteriological, molecular, biochemical and pathophysiological methods. A basic part of the research will be focused on the mechanisms of the diminished susceptibility to penicillin as well as on the structural modification in PG, to elucidate the role of PG modification in the meningococcal pathogenesis. In addition to gaining more knowledge in the field of IMD, the project is also very important from the public health perspective.The development and then implementation of accessible molecular methods to predict meningococcal susceptibility to antibiotics should permit faster and thus improved management of meningococcal infections, with better epidemiological surveillance as we
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Molecular modelling of the cannabinoid CB1 receptor homodimer and its interaction with ligands: the role of membrane cholesterol and the CRIP1a protein' (CannabiDim).

assistant: **Concept**

The cannabinoid CB1 receptor (CB1R) is an attractive molecular target for the treatment of substance abuse, drug addiction, schizophrenia, bipolar disorder, motor dysfunction including Huntington’s disease, as well as cardiometabolic disease and metabolic syndrome.The general aim of the project is to investigate in silico the phenomenon of the homodimerization of the CB1R, the interaction of the CB1R homodimer with ligands,  and to study the effect of membrane cholesterol and the cannabinoid receptor interacting protein 1a, CRIP1a, on the functioning of the CB1R homodimer. The project is intended to verify a set of hypotheses: (i) homodimerization of the CB1R is agonist-mediated; (ii) the interface transmits cross-talk between protomers; (iii) cholesterol promotes CB1R homodimerization; (iv) cholesterol stabilizes the inactive state of the CB1R homodimer; (v) the CRIP1a stabilizes the inactive state of the CB1R monomer; (vi) the CRIP1a hampers CB1R homodimerization. The project involves the following detailed objectives:(1) homology modelling of the CB1R monomer in the active and inactive state;(2) application of protein-protein docking and surface roughness-based scoring to construct a model of the CB1R homodimer in the active, inactive and “mixed” state;(3) all-atom molecular dynamics (MD) simulations of respective dimers and monomers in a lipid bilayer;(4) all-atom MD simulations of the respective dimers and monomers in a lipid bilayer containing cholesterol;(5) modelling of CRIP1a;(6) modelling of the CB1R-CRIP1a complexes applying protein-protein docking and MD simulations;(7) coarse-grained MD to investigate the assembly of CB1R monomers and CB1R-CRIP1a complexes in a lipid bilayer;(8) coarse-grained MD to investigate the assembly of CB1R monomers and CB1R-CRIP1a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The implementation of predictive coding across the auditory hierarchy' to be submitted under Horizon Europe.

assistant: **Abstract**

Posing the brain as a predictive system has become a guiding principle that has proven to be particularly fruitful in the study of perceptual processes. Perception is understood as an inferential process in which the brain combines its noisy sensory input with predictions generated by internal models. In this way, the contents of conscious experience would be determined by the hypothesis about the state of the world, with the highest posterior probability. One popular algorithmic incarnation of the predictive processing ideas is predictive coding, in which the brain implements a hierarchy of generative models, where feedback connections carry predictions and feedforward connections carry prediction errors. The brain would minimize these prediction error by updating its internal models. While compelling, this proposal leaves open several issues.It is not yet clear how a predictive perceptual system could be both sensitive to expected and to surprising stimuli. Bayesian integration of sensory evidence and prior probability of the hypotheses (predictions) might offer an optimal solution. But some authors have argued that Bayesian integration would result in a bias toward the expected. Therefore, the question of how conscious experience emanates from the interaction between predictions and prediction errors remains open.Predictive coding assumes separate neuronal populations representing predictions and prediction errors, which would reside in different cortical layers. This proposal remains largely untested in humans, in particular in the auditory domain.This project focuses on the auditory domain, where the ability to predict the incoming sensory stream is fundamental for making sense of everyday auditory scenes, especially in the presence of noise. I will tackle the afor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'How the expression of moral emotions affects third party punishment' to be submitted under Horizon 2020.

assistant: **Abstract**

Many researchers have suggested that cooperation is made possible by third party punishment (TPP) of free riders. TPP has its own free riding problem, though; it is costly in itself, and people can be tempted to let others incur the costs of punishing cheaters. Thriving research areas are currently seeking to explain how this second-order free rider problem is resolved – that is, how individuals are sufficiently compensated for engaging in TPP. One proposal suggests that individuals gain reputational benefits by punishing noncooperators. Yet the evidence supporting this proposal is equivocal: punishers are sometimes preferred, but they are also often avoided, perhaps because of uncertainty about their motives underlying TPP. Based on recent theoretical and empirical developments on the functions of disgust and anger, we suggest that the expression of these moral emotions can help explain the inconsistency in how observers perceive third party punishers, because emotions reveal information about the punishers’ motives and intentions. The proposed research aims to test whether disgust expressions increases trustworthiness of punishers whereas anger promotes a reputation for punitiveness and aggression. The research would simultaneously shed light on prominent debates about the differences between these emotions. Methods from behavioural economics, such as the third party punishment game and the trust game, will be integrated with methods from the social psychology of emotions used to test the interpersonal effects of emotion expression. Studies will also employ software that enables the collection of data from real-time behavioural interactions. The proposed research and training will enable the applicant, who has made important contributions to the literature on emotions
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Visegrad Initiative for Nuclear Cooperation' in the context of a Horizon 2020 call.

assistant: **Objectives**

After a common expression of willingness to cooperate and legal establishment of V4G4 Centre of Excellence Association, VINCO project represents the next stage of capacity building in nuclear technologies in Central European countries. Participating countries defined already their specializations: helium technology in Czech Republic, design and safety analyses in Slovakia, fuel studies in Hungary and material research in Poland. Having such expertise, the joint development of Gen IV nuclear technologies with the special emphasis on gas-cooled reactors is fully possible. Thus, the main objectives of the regional VINCO project are: (i) development of the principles of cooperation and rules of access to existing and planned infrastructure, (ii) identification of the specific objectives of the R & D activities in the cooperating countries, (iii) description and analysis of the existing research, training and educational equipment and capabilities, (iv) determination of the investment priorities in cooperating countries and (v) setting up of joint research, educational and training projects. It is expected that the joint activities will result in coordination of actions allowing to obtain financing from the Structural Funds available for the Visegrad countries. These funds would allow for a huge increase of mass and modernization of the research potential in the region. Close cooperation with other EU institutions (mainly CEA, France) will ensure better description of the investments needed in Visegrad Region, tightening of pan-European cooperation and strengthening of the role of V4 countries, helping them to evolve from users to the suppliers of R&D capabilities in nuclear technologies. A major expected impact of the project would be setting up of a distributed regional re
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Realization and imaging of superconducting spin-wave optics' to be submitted under Horizon Europe.

assistant: **Abstract**

Spin waves are collective excitations of the spins in magnetic materials. They play a central role in the thermodynamics of magnets and are promising signal carriers in classical and quantum information devices. Spin waves offer non-reciprocal transport, low damping, microscale wavelengths at microwave frequencies, and strong interactions that enable signal conversion. As such, spin waves have raised the hopes of enabling information technology with functionalities and efficiencies beyond those provided by non-interacting particles. A key requirement is realizing efficient, low-damping spin-wave control. A potentially ground-breaking but virtually unexplored method is provided by superconductors. Superconductors have no electrical resistance, precluding damping by eddy currents, and a strong diamagnetism that enables stray-field control of the refractive index governing spin-wave transport. Moreover, superconductors are sensitive to electric currents, magnetic fields, temperature, and light, providing tunability. As such, superconductors provide unique opportunities for realizing low-damping, tunable spin-wave optical devices.I propose to realize and locally study superconducting spin-wave optics. I will create spin-wave-optical devices - mirrors, waveguides, beamsplitters, and resonators  by harnessing the dissipationless superconducting diamagnetism. I will then demonstrate the power of superconductor-control by tuning the devices using electric currents, magnetic fields, temperature, and light. In addition, I propose to use superconductors to engineer spin-wave damping and enter new regimes of flat-band and topological transport. To locally study spin waves underneath superconductors, I will use magnetic imaging based on spins in diamond  a technique pioneered by my
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Genetic mechanisms that determine neuronal progenitor identity in the ventral spinal cord (STEMBRIDGE)' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The most remarkable feature of the Central Nervous System (CNS) is the massive array of neurons that permit the diversity of functional neuronal circuits. The spinal cord contains neurons that integrate and relay sensory information from the periphery to the brain and the neurons that control and co-ordinate motor output. Mature neurons derive from neuronal progenitors that appear in a highly patio-temporal order in different neural regions. A major question in developmental neurobiology is to understand how the developing neural tube becomes patterned into distinct clusters of neuronal progenitors. A second, equally important, issue is to define the genetic mechanisms that govern cell fate determination and subtype specification of cells in the same progenitor pool. The latter question is of important relevance to stem cell therapy for neurodegenerative disorders of the brain and spinal cord.