RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Future Crops for Food, Feed, Fiber and Fuel' (2007-2013).

assistant: **Innovation**

As different sectors – food, feed, fiber, and fuels – compete for land, the yielding potential of the future non-food crops has to be as efficient as possible in order to minimize the competition for land. The main objective of the proposed 4F CROPS is to survey and analyse all the parameters that will play an important role in successful non-food cropping systems in the agriculture of EU27 alongside the existing food crop systems. The work will start (WP1) with the prediction of the future land use in short term (2020) and long term (2030), taking under consideration restrict factors for agriculture and the market demand for non-food crops. The cropping possibilities (WP2) based on regional potential levels, ecology and climate will be determined. This group of non-food crops will be then subjected to a comparative cost analysis with conventional crops (WP3) for the same time framework. Socio-economic impacts, like farmers’ income, rural development, public development, and public acceptance will analyse. Then environmental implications will be assessed compared to their respective conventional products (fossil energy, conversional materials) (WP4). Several environmental impacts will be assessed like soil quality and soil erosion, air quality and climate change, water issues, biodiversity and landscape by using LCA and EIE methods. The regulatory framework of the non-food crops will be considered including existing policies, co-existence and safety measures when the crops used for both food and non-food crops (WP5). The work from WP1 – WP5 will be used for the formation of scenarios for successful non-food cropping alongside food cropping systems (WP6) answering whether a completive bioeconomy is a viable option for EU27. The dissemination (WP7) will be done though the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'AI-CODE - AI services for COntinuous trust in emerging Digital Environments'.

assistant: **Objectives**

The media sector is exposed to and undergoing continuous innovations that occur at a pace never seen before and have a non-negligible impact on citizens, democracy and a society as whole. A significant booster becomes a generative Artificial Intelligence, which already plays and will continue to play a critical role (in a positive as well as negative meaning) in creating and spreading information. Especially in next-generation social media, which refer to the anticipated evolution towards more AI-based decentralised and immersive virtual environments (like fediverses and metaverses), generative AI can become the most prominent enabler of disinformation growth accompanied by a lack of trusted information. Media professionals are not, however, currently well-equipped with supporting tools nor knowledge to operate in such already emerging environments.As a result, there is a tremendous need for innovative (AI-based) solutions ensuring media freedom and pluralism, delivering credible and truthful information as well as combating highly disinformative content. The main goal of the AI-CODE project is to evolve state-of-the-art research results (tools, technologies, and know-how) from the past and ongoing EU-funded research projects focused on disinformation to a novel ecosystem of services that will proactively support media professionals in trusted information production through AI. First, the project aims to identify, analyse, and understand future developments of next-generation social media in the context of rapid development of generative Artificial Intelligence and how such a combination can impact the (dis)information space. Second, the project aims to provide media professionals with novel AI-based services to coach them how to work in emerging digital environments an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'New Concepts for Utilizing a Ubiquitous (Non-)Functional Group - C-H Bond Activation for Increased Efficiency in Organic Synthesis'.

assistant: **Objectives**

C-H activations and related reactions can potentially revolutionize the way organic molecules are made and allow a more efficient use of earth's natural resources. Despite the rapid progress of the last couple of years, many problems like limited scope, extreme reaction conditions (temperature, excess of reagents) or low reactivities and selectivities remain in many cases. In this comprehensive proposal containing a number of projects and work packages, we want to develope new C-H activation methods 1) for the efficient synthesis of heterocycles, 2) for the activation of unactivated C(sp3)-H bonds, 3) by employing newly designed Fe-NHC complexes and 4) demonstrating the application of C-H activation for the functionalization of metal-organic frameworks (MOFs). The realization of these goals would render organic synthesis greener and more efficient and would have an impact on the preparation of compounds in academia and industry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Development of Hydrophobic Windscreen Coating for Next Generation Civil Tilt Rotor' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The HaSU project directly addresses the challenges inherent to design, fabricate, and experimentally demonstrate a new type of hydrophobic coating for the Next Generation Civil Tilt Rotor (NGCTR) windscreen. In HaSU, a durable surface coating on the windshield to shed water will be developed and qualified to maintain pilot's visibility without using wipers. More in details, the HaSU project aims at providing:1. Design and development of a specimen of the NGCTR windscreen substrate having the requested hydrophobic functionalities and performance throughout the whole flight envelope (to be reached in the WP1). 2. Manufacturing of hydrophobic windscreen specimens (to be reached in the WP2).3. Testing and qualification of proposed hydrophobic specimens according to RTCA DO-160 (Environmental Conditions and Test Procedures for Airborne Equipment of proposed hydrophobic specimens (to be reached in the WP3).The proposed technological solutions start at a TRL4 level and will make it possible to reach TRL6 at the end of the project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'AmbiJet: the world’s first and only highly effective plasma-based solution for Europe’s 16 Million periimplantitis patients urgently needing help to avoid losing their dental implant' under Horizon Europe.

assistant: **Concept**

Regular dental check-ups and treatments not only ensure a beautiful smile, but good general health: a healthy oral cavity strengthens the immune system and acts as a barrier against various heart-, kidney-, or lungs-related diseases and diabetes. There is currently no effective solution to treat the 16.3 mn infected dental implants (EU, 2019). Freiburger Medizintechnik GmbH developed the solution dentists are looking for: a disruptive technology for highly effective infection control to fight periimplantitis. AmbiJet® is the world’s first and only plasma-based technology with the ability to kill bacteria on dental implants in-situ. It disrupts the status-quo of medical technologies by preventing the reinfection of disinfected surfaces and shows maximum effectiveness without side nor adverse effects: pharmacological and chemical substances are no longer required. AmbiJet® reduces inflammation, saves dental implants and helps patients live a healthier life.


**Keywords:** Plasma technology,Periimplantitis,Infection control,Reinfection,Dental diseases,Dental implant
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Cryo-EM structural analysis of small nuclear ribonucleoprotein particles (snRNP) biogenesis' under Horizon 2020.

assistant: **Concept**

The spliceosome is a multi-megadalton enzyme that catalyses the excision of non-coding introns from nuclear pre-mRNA. It is assembled from five small nuclear ribonucleoprotein particles (snRNPs) and non-snRNP factors, while each snRNP contains a unique small nuclear RNA (snRNA, U1-U5) and is bound by the heptameric Sm-ring. Acquisition of the Sm-ring is a key quality control step in snRNP biogenesis, defects of which are linked with several human diseases. In humans, snRNP biogenesis requires at least 15 proteins, including the 9-subunit survival of motor neuron (SMN) complex. The SMN complex carries out the regulated and specific loading of the Sm ring onto snRNA. Recent studies have revealed the structure of several key proteins that play a role in snRNP assembly, however the complete structures of either the SMN complex alone or with interacting Sm ring and or the  snRNP as a whole, are lacking and culminate to a big gap in our knowledge of the snRNP assembly. In this proposal, I will reconstitute key steps in snRNP biogenesis in humans and will determine their structures using cryo-electron microscopy and cross-linking mass spectrometry. I will study how the SMN complex specifically loads the Sm-ring onto U1 snRNA, as a model snRNP. Additionally, purification and structural analysis of endogenous SMN complex will reveal SMN complex stoichiometry and validate the in vitro work. The structures will reveal the interacting partners and the structural transitions within the assembled snRNP and will enable structure-guided biochemical and tissue culture validation of SMN complex function, while my background in protein biochemistry and human tissue culture makes me ideally suited to carry out this high-impact project. StructuRNP will provide first insights into the molecu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'AI for Vision Zero in Road Safety', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

IVORY - ‘AI for Vision Zero in Road Safety’ is an industrial doctorates network aiming to develop a new framework for optimal integration of Artificial Intelligence (AI) in road safety research, and train a new generation of leading researchers in the field. It addresses the UN Sustainable Development Goals target 3.6 and the EC Vision Zero strategy, of halving traffic fatalities by 2030 and eliminating them by 2050.IVORY addresses the lack of common understanding of the challenges and opportunities of AI for road safety by means of 4 research goals: it aims to develop (i) responsible, fair and impactful AI for road safety, (ii) new ways of road user support and human-vehicle-environment interaction, (iii) new scalable and equitable AI technologies for proactive infrastructure safety management, (iv) a sustainable knowledge sharing network on AI for road safety. IVORY outputs will not only provide more robust user support through AI in vehicle automation, but will also allow to responsibly and proactively manage the persistent problems of existing conventional, low-automation transport systems, so that new opportunities for global road safety impact can emerge. Moreover, IVORY takes a design-for-values approach for AI in road safety, operationalising the ethical principles of justice and explainability, and providing efficient AI solutions also for disadvantaged groups (e.g. vulnerable road users, low-to-middle-income countries). IVORY consists of 4 academic and 6 non-academic beneficiaries, and 12 associated partners, joining from engineering, data science and ethics of technology disciplines, from 11 countries. 13 young researchers will receive high-level doctoral education, industrial exposure, local training, and 8.5 ECTS of network-wide training on key advanced, co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Quantum Complexity from Quantum Field Theories to Quantum Gravity.' under Horizon Europe.

assistant: **Concept**

Quantum field theories (QFTs) are our best models to describe nature, from new phases of matter to black holes. Still, to simulate them efficiently, we need to know the best ways to create interesting quantum states from the basic building blocks used in computation. This problem necessitates a precise definition of “quantum complexity”, to quantify what is hard and what is easy in QFTs, and its provision is one of the most urgent problems at the interplay between theoretical physics, quantum information and computation.This project aims to develop precise measures of the complexity of states and operators in QFTs and apply them, in the holographic correspondence, as new probes of black hole interiors. Recent attempts to quantify complexity, pioneered by PI and his group, have explored geometric, path integral and Krylov methods, preparing the ground for a universal approach to complexity in quantum systems. Building on this, the project objectives are to: - synthesise and develop complexity measures for QFTs,- formulate them in exact holographic models,- apply them to shed new light on the physics behind black-hole horizons and spacetime singularities.Developing complexity measures in open quantum systems, models with additional symmetries and quantum scars, and quantifying the complexity of modular evolution are among the key milestones to achieve the objectives. Our methods will involve analytical and numerical computations in free and interacting QFTs, including integrability, conformal symmetry, Krylov basis, Arnoldi algorithm, and finally, the AdS/CFT correspondence and quantum gravity. This interdisciplinary and timely project will push the boundaries of our understanding of QFTs and black holes. The new tools that we will develop will allow us to chart the compl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Improving Translational Research Potential at the Institute of Biomedicine of Seville'.

assistant: **Innovation**

The ITRIBIS project is envisaged to improve research at the Institute of Biomedicine of Seville (IBiS) and to help this center to become a reference of biomedical translational research applied to prevalent diseases in Southern Europe. It also aims to boosting the transfer of results to the clinical setting and to the local biotechnological companies, thereby resulting in the production of tangible benefits for the region. The ITRIBIS is focused in a major translational research line, cell degeneration (brain, heart, cancer), accompanied by another, more specific, focusing on antimicrobial resistance.  These research lines comprise the four main areas in which IBiS is currently organized. The Institute is tightly linked to the University Hospital Virgen del Rocio (HUVR), one of the largest in Spain. ITRIBIS will improve IBiS research quality and potential through several specific actions: [1] Recruitment of six senior scientists with the following professional profiles: a) A clinician and a basic scientists working on the molecular bases of Alzheimer disease, with proven experience in phase I/II clinical trials. The doctor will direct the “dementia clinic” of the HUVR, and the researcher will develop epidemiological and experimental studies on neurodegenerative diseases, particularly on those of ischemic and vascular origin. b) Two basic/translational scientists working on cardiovascular research and one on antimicrobial resistance. c) An expert scientist in bioinformatics, to lead the new bioinformatics platform. [2] Reinforcement of the IBiS Core Facilities through the acquisition of research equipment and the recruitment of five technicians that will develop the areas of Bioinformatics, Imaging, Proteomics, and Data storage. These measures will complement and potenti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Functional Nanoscale Coordination Polymers: Controlled Growth by Metal-Containing Block Copolymer Templated Self-Assembly' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Coordination polymers are infinite arrays of bridging ligands bound to two or more transition metal ions. The potential application of coordination polymers in the areas of materials and nanoscience is significant as their properties can be tuned through variation of the transition metal ions and bridging ligands. To date, research in the area of functional nanoscale coordination polymers has been limited to amorphous (spherical) and crystalline (non-spherical) examples and the controlled growth of coordination polymers has not been realized. We propose the use of metal-containing diblock copolymer templates, which self-assemble in a number of different morphologies depending on the volume fraction of the blocks, to influence the structure of coordination polymers on the nanoscale, and for the first time demonstrate control over their size and shape. Our approaches will afford multifunctional materials with highly tunable properties, and the incorporation of diblock copolymers will allow for the rational design and controlled growth of nanoscale coordination polymers. This highly interdisciplinary and multidisciplinary research proposal requires a wide range of skills and this is exactly the mix possessed by the applicant (ligand design, coordination chemistry, stable-radical chemistry, electrochemistry, and molecule-based magnetism) and the host laboratory (polymer chemistry, materials chemistry, and nanoscience). The proposed research will bring a promising young researcher to Europe, and will lead to a new area of functional polymer and materials research where a range of potential applications are envisioned.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Molecular mechanisms leading to genome-wide DNA demethylation during epigenetic reprogramming' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Epigenetic reprogramming is a developmental process involving both genome-wide DNA demethylation and chromatin remodelling. Under physiological conditions it occurs at distinct stages of normal embryonic development. However,  under in vitro conditions induction of this process can restore pluripotency in somatic cells, and in aberrant situations a similar dedifferentiation process can initiate carcinogenesis. While the kinetics of the reprogramming that occurs in the course of normal development has been well documented, initial steps inducing this process and how DNA methylation marks are removed in vivo remain elusive. The involvement of DNA repair mechanisms in DNA demethylation during epigenetic reprogramming has been recently suggested. The presented project proposes to investigate the upstream events initiating epigenetic reprogramming by using both in vivo and in vitro approaches. We will focus on recently discovered candidates involved in 5-methylcytosine hydroxylation and will investigate a possible involvement of this modification of 5-methylcytosine in the epigenetic reprogramming during mouse development. We will also examine the potential repair enzymes able to remove this epigenetic mark in order to highlight other protein partners involved in this process. Data obtained on this pathway will not only enrich our understanding towards developmental reprogramming, but also enhance our ability to manipulate cell fate in vitro.