RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Innovative stunning technology based on a natural anesthetizing agent in ice to improve animal welfare and extend shelf-life of farmed fish'.

assistant: **Concept**

CUBI-PLAYA S.L. is a Spanish SME dedicated to ice manufacture, currently employing 39 people. We are specially targeted to the fish sector. We supply high quality ice to fisheries, aquaculture companies and fish processing factories, with the result of a close working relationship with main stakeholders. It is well known that stress situations adversely affect muscle quality, especially during the last period of fish life: slaughter. Traditional slaughtering process involves the death by asphyxia in ice or air, which exposes fish to substantial suffering over excessive periods of time. The distress suffered results in detriment of fish flesh quality and shelf-life, besides imposing avoidable suffering to fish. A pre-stunning phase is therefore recommended, to rapidly cause loss of consciousness and sensibility without pain. However, most of the slaughtering procedures used in fish farm conditions nowadays do not involve a stunning phase. In collaboration with experienced researchers, we have developed ICE2LAST, an integrated solution to speed up the stunning/sedation phase of farmed fish before slaughter, which results in a longer shelf-life and better flesh quality. Fish stunning is caused by an anesthetizing natural substance. When included into crush ice, it causes the complete stunning of the fish in less than 1 minute. By shortening the stunning process, fish flesh quality improves and its spoilage can be delayed more than 50%, compared to traditional slaughtering methods. ICE2LAST is a cost-effective and easy to handle solution, whose implementation leads to enhance fish food quality, reduce fish losses and improves animal welfare.  EU is expected to increase its fish food domestic production, particularly through aquaculture promotion. With projections of a 4% an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Microglia-neuron communication in health and disease' (NeuroTalk2Mi).

assistant: **Concept**

Microglia are the resident immune cells of the brain, display extensive heterogeneity, and contribute to a wide range of cellular processes in both homeostasis and disease. They play a major role in the pathogenesis of Alzheimer’s disease (AD), the leading cause of dementia and a major cause of mortality worldwide. Microglia closely interact with neurons and modulate their function with high regional specificity, making them potential culprits behind the neuronal damage in AD. However, exactly how microglia and neurons interact and communicate, and how these interactions change in disease is not known. I hypothesize that an early hallmark of AD is the changing interactions between microglia and neighboring cells such as neurons, which contributes to progress of the disease and ultimately results in synaptic and neuronal loss. I will test this in human microglia by using a unique human xenotransplantation model, whereby I transplant human pluripotent stem cell-derived microglial progenitors into the cortex of healthy and AD mice. Using RABID-seq combined with 10X Genomics to barcode microglia and subsequently trace their interactions with single-cell resolution, I will precisely map the interactions of distinct subsets of microglia and neurons, to determine homeostatic molecular networks and how cell-to-cell communication is altered in the early stages of AD. Ultimately, this will allow me to identify specific molecules and molecular pathways which can be manipulated to support a beneficial function in microglia, while blocking detrimental effects, to protect neurons and prevent, slow, or ameliorate the disease. Given that microglia are involved in normal brain development and multiple neurodegenerative diseases, finally dissecting how they interact with other cells of t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Recommendations for Internet Usage on 2.5G and 3G' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The objective of the present proposal is to study what technical measures must be taken in order to adapt the existing wired Internet to the new 2,5 and 3G mobile networks, and to elaborate a set of final recommendations addressed to content and service providers, application developers and operators in order to make the transition from wired to wireless services as simple and as cost effective as possible. The study will examine key interoperability issues between different networks and services platforms, including terminal equipments, as well as related security issues. The study will be developed bearing in mind the final goal of providing the final users with seamless end-to-end provision of services and applications. To reach the objective of the study, a set of mechanisms to facilitate the usage of Internet over wireless networks will be proposed and evaluated.Work description:In order to reach the objective of the study, a set of mechanisms to facilitate the usage of Internet over wireless networks will be proposed and evaluated. The work will be based on a first formulation of scenarios that will be assessed by means of pilots and/or theoretical studies. Pilots will be prepared on 2,5G mobile systems to verify the hypothesis formulated. For 3G mobile systems, the hypothesis will be theoretically assessed. One concern is how to adapt current contents to the mobile Internet, and therefore how to bring content down to small devices. Compression is already widespread and proven for fixed-Internet applications and can be applied to wireless networks. Compression will help minimize the amount of data sent to the air and therefore the costs of the services. The TCP/IP protocol suite and the HTTP are not optimised for the properties of wireless links These protocols ma
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Leak detection and reliability-based life prediction of water piping' (LEAKING).

assistant: **Concept**

Ca 1/3 of water provided by EU companies is lost by leakage. This raises health, safety, economic and sustainability concerns. Improved leak detection methods in connection with adequate decision support software to optimise spenditure of resources may contribute substantially to mitigate this critical situation. This work will develop an innovative leak inspection equipment for water pipelines based on microwave technology, and a decision support system, that will store available data on the pipe lines, and will receive input from leak inspections. It will perform condition assessment to determine residual lifetime.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'A multi-dimensional feature space for predictions in the brain'.

assistant: **Innovation**

The brain uses prior experiences to make a “best guess” of the noisy and ambiguous information in the world around us. These predictions are constantly updated as new sensory information becomes available, yet the computational resources of the brain are limited. What is a viable model for representing and updating predictions in the brain that is both computationally efficient and neurobiologically plausible? I hypothesise that the brain represents predictions by decomposing them into their constituting features and pre-activating those features considered instrumental in explaining the sensory input, thereby allowing to update only parts of the prediction without revising the whole prediction. The proposed project fuses concepts of multi-dimensional feature encoding, cortical processing hierarchies and activity-silent working memory to develop a computational model of prediction and error coding using artificial neural networks. The implications of this model will be empirically tested in human visual perception using functional magnetic resonance imaging with laminar precision. This project aims to gain a deeper understanding of the compositionality of predictions as a building block of fast and accurate perception and bears the potential to transform our understanding of the neural mechanisms giving rise to predictive processes. The project will be carried out at the Donders Institute for Brain, Cognition and Behaviour in the lab of Floris de Lange, a leading expert in the field of predictive processing. As an MSCA postdoctoral fellow, I will conduct cutting-edge research at the intersection of psychology, neuroscience and artificial intelligence, which will give me the opportunity to hone my methodological and management skills, as well as develop my own research p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'A Demonstration of 4D Digital Avatar Infrastructure for Access of Complete Patient Information'.

assistant: **Innovation**

Owing to the highly fragmented health systems in European countries, gaining access to a consistent record of individual citizens that involves cross-border activities is very difficult. MyHealthAvatar is an attempt at a proof of concept for the digital representation of patient health status. It is designed as a lifetime companion for individual citizens that will facilitate the collection of, and access to, long-term health-status information. This will be extremely valuable for clinical decisions and offer a promising approach to acquire population data to support clinical research, leading to strengthened multidisciplinary research excellence in supporting innovative medical care.<br/>MyHealthAvatar will be built on the latest ICT technology with an aim of engaging public interest to achieve its targeted outcomes. In addition to data access, it is also an interface to access integrative models and analysis tools, utilizing resources already created by the VPH community. Overall, it will contribute to individualized disease prediction and prevention and support healthy lifestyles and independent living. It is expected to exert a major influence on the reshaping of future healthcare in the handling of increased life expectancy and the ageing population in Europe. This complies with the priority and strategy of FP7 ICT for healthcare, and constitutes a preparatory action aiming at the grand challenge on a Digital Patient", which is currently the subject of a roadmap in the VPH community.<br/>MyHealthAvatar places a special emphasis on engaging the public. It has huge implications to the society both socially and economically. The initiative of designing a personal avatar can potentially change the way we think, communicate and search for information. Meanwhile, the acc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Rethinking the Efficiency-Redistribution Trade-Off:  Taxes, Transfers, and Household Inequality'.

assistant: **Concept**

Income and wealth inequality have surged in OECD economies over recent decades, sparking renewed debates on the optimal tax-and-transfer system. How should governments design redistribution to the poor? Which taxes should be used to finance the safety net? This proposal consists of three projects combining rich quantitative models with analytical and empirical insights to push the frontier on our understanding of the efficiency-redistribution trade-off. Part I explores how to design income support to the poor. Since the 1980s, many OECD economies have reformed their safety net and introduced work requirements for several welfare programs. Work requirements foster efficiency as they incentivize labor supply but limit redistribution to the poorest. We document the shift in the distribution of transfers across households in the United States since the 1980s and quantify the optimal balance between standard means-tested transfers and those conditional on work requirements.Part II explores how to adjust consumption taxes in recessions. Consumption taxes make up a large share of fiscal revenue in OECD economies, yet their regressive nature raises distributional concerns. Temporary consumption tax cuts have been recently proposed to fight recessions, with the joint goal of easing the burden on the poor and stabilizing the economy. We theoretically and quantitatively analyze the stabilization properties of temporary consumption tax cuts.Part III explores how to raise revenues from the wealthy. Capital income taxes have been regularly proposed to finance redistribution, with no consensus on their efficiency cost. High capital income likely reflects skills of investors selecting productive private businesses, but it may also stem from the market power of wealthy investors.  We ex
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Development of a novel multiple automated DNA synthesizer (for 10-25 oligos simultaneously) allowing production of large number of inexpensive oligonucleotides for application in clinics and diagnostics' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Construction and demonstration of a multiple DNA sythesizer prototype to enable diagnostic laboratories to produce many nucleotides simultaneously, on a user friendly simply operated device cost reduction for synthesis of oligonucleotides for clinical and diagnostic purposes. to provide molecular diagnostic tools for clinical applications, e.g.: fluorescent and chemiluminescent based systems for the diagnosis of neurodegenerative disorders due to CAG-repeat expansions reverse dot-blot chemiluminescent based systems for the diagnosis of cystic fibrosis in the different regions of Europe. Production of cheap dye-labelled microsatellite marker sets for automatic genetic mapping of the human genome. Analysis of mutations occuring during tumour development, devising new medical treatment and identifying risk factors.Clinical laboratories will need synthesizers which can produce many different oligonucleotides simultaneously, in a fast and inexpensive way. The current standard synthesis technology is limited to synthesis of 3-4 oligonucleotides simultaneously The high price per oligonucleotide renders extensive clinical analyses expensive. Today's synthesis chemistry and synthesizer technology are not suited to meet future demands. To meet these demands fast multiple DNA synthesizers resulting in low cost oligonucleotides, are required. Based on the concept of the EMBL synthesizer the production of an industrial prototype of a 10 column device, with optional upscaling to 25-40 columns, is one main goal of the project. The technology will reduce DNA synthesis costs by a factor of 10, while increasing the throughput by nearly an order of magnitude compared to standard commercial devices. Among the use of oligonucleotides as a diagnostic tool the most important is their role in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Discovering the circuit and molecular basis of inter-strain and inter-species differences in learning' (SMART) targeting Horizon Europe.

assistant: **Abstract**

Across the animal kingdom, closely-related species can differ in their learning ability, as can differentindividuals of the same species, but the underlying causes of these differences are poorly understood.Differences in learning could be due to different structural and functional properties of learning circuits whichin turn result from different patterns of gene expression. However, identifying homologous learning circuitneurons in different species for comparing their synaptic connectivity, cellular-resolution functional propertiesand transcriptomes is challenging in larger brains.We have identified a strain of Drosophila melanogaster larvae that learns faster (after fewer training trials)than others and a closely related Drosophilid species that learns faster than the D. melanogaster strains. Wewill use this tractable genetic model system to compare learning circuits in faster/better and slower/worselearnerstrains and species, in particular, their synaptic resolution connectomes; cellular-resolution activitymaps; and transcriptomes. We will then screen the differentially expressed genes to identify those that improvelearning and determine the way in which they affect connectivity and functional properties of learning circuits.This project will reveal the architectural features of learning circuits that enhance learning and memory, aswell as the molecules that can transform slow/worse- into fast/better-learners and their mechanisms of action.Uncovering the underlying structural, functional and genetic causes of variability in learning will not onlyhave a major impact on neuroscience but could also potentially inspire the development of better architecturesand algorithms for artificial intelligence and provide new avenues for treating learning and memory deficits.


*
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for '[SCIMIN-CRM] Sustainable & CIrcular Production of MINeral Critical Raw Materials' in the context of a Horizon Europe call.

assistant: **Objectives**

Europe must reduce its dependence on raw materials (RM). Over 100,000 MWFs hold vast potential for critical and non-critical RM, while addressing environmental concerns. SCIMIN-CRM aims to enhance access to primary and secondary RMs in Europe by leveraging MWFs' untapped potential. This involves developing a streamlined ‘fast-path’ process and a collaborative digital platform for smart assessment, alongside technology development for RM valorisation in various MWF types across Spain, Sweden, Austria, and Bosnia and Herzegovina. A roadmap will prioritize extraction of valuable CRM like fluorspar, baryte, REEs, and bauxite/aluminium, among others non-critical but highly valuable materials (e.g. copper, aggregates). SCIMIN-CRM will transform discarded materials into valuable resources, increasing valorisation from near 0% to 5% and reducing assessment time by -83%. It will deliver two mobile crushing technologies, a collaborative digital platform, and four cutting-edge processing methodologies. By 2030, the new process aims to become the standard for sustainable MWF assessment aligned with the CRM Act. The project will promote market adoption of sustainable solutions, offer capacity-building programs, enhance social acceptance, and foster industry collaboration. Ultimately, SCIMIN-CRM seeks to boost EU's access to RMs, improve economic performance, enhance recovery rates, and ensure responsible supply, contributing to long-term sustainability and competitiveness. The consortium involves 21 participants from 10 countries spanning the MWF value chain.


**Keywords:** Mining Waste Facilities, critical raw materials, valorisation, environmental assessment, resource-efficient, sustainability, standards, digital platform, recovery, Raw material, CRM, fluorspar, bauxit