RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Development of sociality and social relationships and maintenance of social structure over generations in the closest evolutionary relatives of humans, the great apes', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Sociality is an evolved trait, which forms the basis of primate societies. It influences individual survival, reproduction, access to information, and disease transmission. As early-life experiences have long-term consequences, knowledge of individual developmental history has contributed well to understanding the factors that underlie variation in individual health, longevity, resilience to internal and external stressors, amongst other crucial aspects of an animal’s life. Therefore, studying aspects of individual development is fundamental to understanding how individuals become well-adapted to their environment. Great apes live in complex societies with constantly changing opportunities for associations and interactions, for which they make complex cognitive decisions just like humans. As they are our closest evolutionary relatives, long-term developmental studies on them are indispensable to understand how the development of the social life of humans evolved. National and international collaborations focused on data and knowledge sharing for comparative studies on great apes will help to overcome the current gaps in our knowledge about human social evolution. The future fellow will collate two decades of fine-scale observational data collected on individually identified great apes from birth until the start of adulthood from four great ape projects. The aims are to 1. investigate, at the individual level, the development of sociality and social relationships, 2. investigate, at the population level, social inheritance of social structure over generations, and 3. develop a general theory of social structure maintenance. This action will be the first to take a large-scale, data-intensive, and comparative approach to studying the social life of immature great apes usin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Investigating Ortho-para coNversion of TRihydrogen cAtion in sPace' (IONTRAP) targeting Horizon Europe.

assistant: **Abstract**

The simplest polyatomic molecule, trihydrogen cation, serves as a useful benchmark for fundamental quantum chemistry and has profoundly impacted astronomy. It was first detected in the interstellar medium in 1996, and has been recognized for its pivotal role as a universal proton donor and an initiator of ion-molecule chemistry producing many of the molecules detected in space.Interstellar chemistry is an exciting chemical playground of thermodynamics and kinetics as the molecules can require up to days or even weeks to reach thermal equilibrium in the low-density cold environments. A longstanding astrochemical conundrum has been the population distribution between the two nuclear spin modifications of trihydrogen cation, ortho and para, as it has important implications for its use as a cosmic ray ionization probe. In reactions involving identical particles/fermions, like trihydrogen cation, restrictions are introduced due to the Pauli principle which can significantly increase the time required to reach a thermal equilibrium. This makes the chemistry, especially the kinetics, of the ubiquitous trihydrogen cation in these regions both exciting and challenging to understand in our terrestrial laboratories. Here, I propose to use a cryogenic ion trap to isolate the nuclear spin states of trihydrogen cation which is the first of its kind for a polyatomic molecule recently developed in the host’s group. Beyond the intriguing fundamental chemical physics of this system, isolation of the nuclear spin states will be exploited to study the quantum state-specific kinetics down to 10 K for the reaction between molecular hydrogen and trihydrogen cation which is one of the most common bimolecular reactions in the universe. Performing these challenging measurements with a critical i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'ICTethics. An Interdisciplinary Approach for Addressing Ethical, Social and Legal Aspects of ICT' in the context of a Seventh Framework call.

assistant: **Objectives**

There is an urgent need for a systematic analysis of the ESLA aspects of Research in ICT, of the same type as developed by the ESLA (Ethical Social and Legal Aspects) working group on biotechnology, established by the European Commission in the early 1990s. Some ESLA-like reflection on ICT is ongoing, but is fragmented and ad hoc. It risks lagging behind technological developments that are already moving towards a ""post PC era"" and the internet of things. It is necessary to think through the ethical issues before developments proceed rather than afterwards when science and industry may be constrained by regulations that deter innovation and hamper just and balanced deployments. A systematic ESLA reflection will also assist industry in reflecting upon the impacts of new developments in science and technology and what reactions they may engender amongst publics in different cultures and polities.The project will perform an integrated ESLA of identified strategic ICT developments that have the potential to revolutionize private and social life over the next five years. It will analyse (a) the development of intelligent environments, (b) the convergence of the physical, the mental and the virtual, (c) the internet of things and (d) ICT for security. It will focus on flagship developments like the personal health system, the humanoid robot assistant, RFID and biometrics identification.The results of the study will be translated into a targeted feedback to all stakeholders involved, to the public at large and to general innovation and e-Inclusion policy. This multi-actor engagement and participation strategy is key to the proposed work of the project in promoting ESLA informed dialogue on the impacts of future ICT innovations.The work will be carried out by a consortium of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The role of social behaviour in mate choice' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Cooperation is at the very base of our society and it has been argued that the adoption of cooperative breeding by our hominin ancestors provides the most parsimonious explanation for the origin of human hyper-cooperation. In addition, in humans, cooperation seems to bring not only kin benefits but also sexual benefits by influencing partner choice. Whether cooperative behaviour also influences partner choice in wild animals remains almost unknown. Two powerful tools will be used in this project, SOCIAL MATCH, to answer this question. First, statistical analyses of a long-term database including both cooperative behaviour and mating success and, second, new technologies to determine if and how cooperative behaviours can be sexually selected. In my project SOCIAL MATCH, I will focus on the cooperative behaviours of a natural population of a passerine under long-term investigation, the Sociable Weaver (Philetairus socius). I will test the predictions that if cooperation brings sexually selected benefits then it should be linked to mating success, condition and should be advertised. I will measure condition developing automated detection of individual mass. I will quantify the vocal behaviour of cooperating birds using on-board miniature microphones and classify the obtained vocalizations with machine learning algorithm. With the acquired information I will be able to design a playback experiment to explore the links between vocal advertisement of cooperation and probability of finding a mate. Therefore, I will quantify every step from the decision of helping to the breeding phase. Despite their explicit evolutionary relevance, the consequences of sexually selected direct benefits on promoting and maintaining cooperation have remained largely unexplored. SOCIAL MATCH aims
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Interactions of Breast Cancer Cells with Macrophages in Controlled 3D in vitro Microenvironments' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The leading cause of death for cancer patients is metastasis. During metastasis, cancer cells interact with various molecules and cells. It has been shown that a group of macrophages facilitates metastasis. Our goal is to determine the mechanism of interaction between epidermal growth (EGF) produced by macrophages and epidermal growth factor receptor (EGFR) expressed by breast cancer cells.Soluble EGF or macrophage conditioned medium does not stimulate breast cancer cell invasion into collagen matrix and 6 kDa EGF is not detected in conditioned medium or cell lysates. Various growth factors are known to bind the extracellular matrix (ECM) and cells can move by haptotaxis (chemo-attractants are substrate-bound). What is more, breast cancer cells do not invade into collagen matrix when macrophages are not present. Based on the above, we will test the following hypotheses:1) Breast cancer cells show chemotaxis to freely diffusing EGF in ECM.2) Breast cancer cells show haptotaxis to ECM bound EGF.3) Breast cancer cells are stimulated by EGF on the cell surface of macrophages.We will use UV lithography to prepare 3D microenvironments for cell culture and use confocal fluorescence microscopy to assay cell behavior and examine the ECM of macrophages. If EGF is soluble in 3D matrix, breast cancer cells will show increased motility with increased proximity to macrophages. If EGF binds to ECM, then ECM produced by macrophages will be able to stimulate breast cancer cell motility via stimulation of EGFR. If EGF stays on the surface of macrophages, breast cancer cells will not invade the matrix without direct contact with macrophages.This interdisciplinary project will establish an experimental system to study interactions between different cell types and will help develop novel di
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Towards understanding cerebral small vessel disease: Innovative, MRI-based, functional markers to discover the terra incognita between large vessels and macroscopic brain lesions'.

assistant: **Innovation**

Small vessel disease (SVD) causes 25% of all cerebral strokes and is a major cause of cognitive decline (dementia) and functional disability (ageing) in the elderly. Two important challenges hamper the development of effective treatments. First, still little is known about the mechanism by which SVD leads to macroscopic, ischemic brain damage and, thus, to cognitive decline. Second, the current clinical markers and image-based markers of SVD do not reflect SVD itself, but macroscopic brain damage secondary to SVD. Unlike large vessels, small vessels are not visible with current imaging techniques, which leave, thus, a ‘terra incognita’ of small vessel pathology between large vessels on the one hand, and macroscopic brain damage on the other. The aim of this program is to remove the major current obstacle towards developing effective treatments for SVD, by innovative magnetic resonance imaging (MRI) techniques that yield non-invasive markers of small vessel (dys)function in the human brain. I will use two innovative sets of image-based markers to discover the ‘terra incognita’. The first set comprises pulsatile tissue motion, strain and potential pulsations in the capillary flow, recognizing the role of stress and strain in cell function (including endothelial cells and neurons). The second set uses the perivascular fluid as an endogenous marker of the blood-brain-barrier function, which is located in the endothelium of the small vessels. These innovative, image-based markers will open a window towards the mechanism by which SVD leads to brain damage. Further, these markers will enable the selection and monitoring of patients who are eligible for new treatments. I will obtain the required sensitivity and resolution, by exploiting the benefits of high field MRI (7T). I am
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Plasma Medicine against Actinic Keratosis' under Horizon Europe.

assistant: **Concept**

The quality of human (and veterinary) health care systems substantially depends on key innovations. Often, these were driven by the field of physics, followed by interdisciplinary and inter-sectorial actions in engineering, chemistry, biology, and medicine, such as X-rays in medical diagnostics, ionizing radiation in cancer treatment, and femtosecond lasers for precision surgery. Medical gas plasma technology was introduced to human health care a decade ago. Today, accredited medical plasma devices are in daily operation in dozen dermatology centers in middle Europe to improve wound healing. In addition, physical plasmas were shown to inactivate cancerous cells. Actinic Keratosis is a skin disease affecting millions of Europeans and making them prone to invasive and deadly skin cancer. Many of the available treatment options are associated with low efficacy, pain, risks, and/or high costs. Medical gas plasma technology is operated at body temperature and applied painlessly, cost-effectively, and without notable side effects. Gas plasma has been suggested to be active on high-grade cancer cells, but its activity against premalignant cells, as in Actinic Keratosis, is unknown. By using beyond state-of-the-art plasma multijet technology, the primary technical objective of PlasmACT – Plasma against Actinic Keratosis – is to support skin cancer prevention by medical gas plasma therapy of Actinic Keratosis. PlasmACT does so by educating a new generation of application-oriented scientists that are exposed to questions and findings from different scientific fields (interdisciplinary from physics over chemistry and biology to medicine) and capable of addressing questions in view of both academic as well as business needs (inter-sectoral) while incorporated in a vivid and product
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Optical studies of carrier dynamics in v-groove quantum wires and quantum dots' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

The project aims to provide a detailed understanding of V-groove quantum wires and quantum dots, so growth and processing techniques can be optimised. These techniques will be used for the development of devices such as transistors and lasers. Further on laser structures based on V-groove quantum wires will be investigated. Several methods of modern optical spectroscopy such as cw and time-resolved photoluminescence, absorption, Raman spectroscopy and near field optical microscopy will be applied in order to ascertain information on electron states, electron-hole recombination and the role of electron hole correlation and carrier-phonon and carrier-carrier scattering in V-groove quantum wire structures. The work will be done in the framework of a co-operative effort between Clarendon Lab., Oxford, and the Institute for Thin Film and Ion Technology (ISI), Research Centre Juelich GmbH, Germany. The research group at ISI works on growth, patterning and electrical characterisation of V-groove quantum wires and quantum dots.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Veterinary Decision Support System by Rapid Bacterial Infection Detection (RAID)'.

assistant: **Innovation**

Development of multidrug-resistant bacteria represent an increasing threat for human and animal health. These bacteria strains are developing mainly due to the unjustified use of antibiotics both for humans and animals. That is why, from 2013 in the European Union, antibiotics can only be added to animals for treatment (not preventive!) purposes, after unambiguous diagnosis of the disease by a veterinarian. This process is beneficial for supressing antibiotic use, but results in high costs and time loss for farmers. The incontrovertible proof of bacterial infection is carried out by culturing method, which takes 24 to 72 hours and costs between 10-50 euros. Our innovation, RAID is Veterinary Decision Support System (RAID), does not require culturing and thus can detect bacterial infection within maximum 2 hours at affordable cost. We have successfully demonstrated our method with an independent veterinary examination under real conditions (TRL=7), developed a stepwise market introduction strategy: first, intensive poultry farming is targeted, as the bacterial infection is the most serious problem in this segment. Potential buyers have been identified, several of them expressed their interest to the project. We submitted a patent application about RAID method. In this phase 2 project, we aim to carry out all essential steps for market introduction: increasing the number of detectable bacteria to at least 50, increasing the reliability to at least 98%, improving and automating sample processing method, establishing a mobile RAID laboratory for satisfying the need of small farmers and veterinarians, who cannot invest to buy large devices and using it for demonstration purposes, validating and certifying our method. We aim to refine our business plan and to obtain tangible
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Hybrid Urban Modernities' (Hybridities).

assistant: **Innovation**

The theory of urban space in cities widely referred to as Middle East-North African has been grounded on a spatial dichotomy shaped by the binary opposition of tradition and modernity. This attitude has dominated urban studies, design practices, and policymaking. Literature which challenges this domination has been largely marginalised. To dislocate this marginalised discourse into the core of the global urban theory debate, this project uses the concept of space ordering and its two constituent themes of privacy and interiority to articulate an alternative, temporally and locally hybrid, theory of urban space which builds on the empirical evidence from the actual urban life in two cities of Casablanca and Tehran. The research employs a methodological bricolage approach to address its interdisciplinary nature. It utilises critical discourse analysis to investigate global debates on the spatial dichotomy of interior/exterior-public/private, and de-construct their manifestation in the (re)production of urban space in two case study cities of Tehran and Casablanca. It then develops a place-specific framework for empirical study of space ordering in two realms of materiality and everyday practices using a wide range of advanced methods. This framework will be applied to four case study neighbourhoods through intensive empirical fieldwork to explore whether and to what extent historical spatial logics are materially and socio-culturally (re)produced and practiced in the contemporary urban space. The findings will be synthesised to formulate an alternative theory of space ordering for the MENA cities which is hybrid, place-specific, and empirically-informed. Policy and planning implications will be incorporated into two Policy Handbook documents for Tehran and Casablanca. Fin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'The Enterprise Europe Network Baden-Wuerttemberg - Targeting Innovation from Baden- Württemberg for Europe'.

assistant: **Objectives**

BW-KAM 5 will implement tested and tailored innovation management services and tools to enhance innovation managementcapacities in Baden-Württemberg's (Germany) SMEs that have the potential to grow and internationalise. The services will be adapted to the needs of the SMEs and also market requirements in order to provide innovative products and services to Europe’s markets. Key Account Management will be provided to SME beneficiaries from the EIC pilot by identifying and matching SME owners with coaches and investors in order to bridge knowledge gaps or financial requirements. The region covered is Baden-Württemberg in southwest Germany, which has been served by the Enterprise Europe Network Baden-Württemberg consortium for the last ten years.


**Keywords:** Innovation Management