RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Holistic, extensible, scalable and standard Virtual Factory Framework' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The project uttermost objective is to foster and strengthen the primacy of Future European Manufacturing by defining the next generation Virtual Factory Framework. The VFF will promote major time and cost savings while increasing performance in the design, management, evaluation and reconfiguration of new or existing facilities, supporting the capability to simulate dynamic complex behaviour over the whole life cycle of Factory, approached as a complex long living Product. Thus the project will research and implement the underlying models and ideas at the foundation of a new conceptual framework designed to implement the next generation Virtual Factory, also meant to lay the basis for future applications in this research area. This approach identifies four key Pillars: a Reference Model for factory planning, based on the new industrial key paradigm “Factory as a Product”; the VF Manager core, meant to handle the common space of abstract objects representing the Factory; a set of decoupled Functional Modules for supporting the factory design, reconfiguration, evaluation, management, … and a Integration of Knowledge at different layers as engine for the modules aiming at giving reality to the envisioned Learning Factory. The Virtual Factory, deployed according to the VFF concept, has to be permanently synchronised with the Real Factory aiming to achieve time and cost savings in the design, ramp-up, management, evaluation and reconfiguration of the Real Production itself. The proposed pillars foster the implementation of a holistic, modular, open and scalable Virtual Factory meant to achieve clear, well identified and measurable goals for the real production system according to quantitative indicators/measures: Time for factory design, re-configuration, re-engineering -50%
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'HIGH-PERFORMANCE GLASS-BASED COATINGS'.

assistant: **Innovation**

The available industrial processes for depositing thick glass coatings (enamelling and glazing) have serious disadvantages. The coatings are low strength, temperature-sensitive materials cannot be coated and also large components or structures outside cannot be coated.Furthermore, the processes are low technology, vulnerable to competition from low-wage economies and consequently are in decline. The proposal will develop a new integrated process based on modified plasma spraying and combustion flame spraying coupled with infrared crystallization. It is aimed at overcoming the weakness of the available processes and widening application of the glass coatings. The proposed project will develop high-performance Nan structured glass-ceramic coatings and glass-based nanocomposite coatings. These have not been made before. High-strength glasses have high fuse temperatures and cannot be coated onto metal substrate by traditional enamelling. The proposal will employ recent sol-gel techniques to make Nan structured particles, which will be spray-dried to feedstock powder and then plasma (or combustion) sprayed. The rapid thermal cycle of spray-deposition preserves the Nan structure and suppresses crystallization. Near infrared radiation immediately after spraying will be used to control the nucleation and growth of the amorphous phase to produce Nan structured glass-ceramic coatings. For glass-based Nan composite coatings, thenanoparticles will be added to the base glass at the gel stage. Computational modelling will facilitate the understanding of the fundamental processes, enhance control and provide a science-based methodology for equipment design. The new technology will allow high-performance glass coatings to be produced with potential applications in, for example, machine
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Translational control in infection biology: riboproteogenomics of bacterial pathogens' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

My recent findings revealed translation of numerous previously unidentified (small) open reading frames and expression of alternative N-terminal proteoforms when studying bacterial translation. This proposal aims at unraveling the repertoire of bacterial pathogen proteoforms employed to establish a successful infection in a mammalian host cell.While deep sequencing has enabled the study of gene expression at the transcript level in both pathogen and host simultaneously, the depth of sequencing has so far proven to be unsatisfactory. Moreover, the study of bacterial proteome changes upon infection remains highly unexplored because of the higher proteome complexity of the host cell compared to the pathogen. These challenges clearly stresses the need for novel strategies based on complementary proteogenomics approaches enabling translation control studies in bacterial pathogens in a host context .I here propose the development and application of a complementary cutting-edge proteogenomic toolset which will enable for the first time targeted systematic genome- and proteome-wide surveys of bacterial transcriptional and translational activity during actual host cell infection. This ambitious endeavor will lead to:I) Establishment of dual Ribo-seq that allows the selective isolation of host or bacterial ribosomes, enabling to study the bacterial translatome in a host cell context.II) Development of tailored proteomics strategies permitting the selective isolation of (nascent) bacterial protein N-termini and enrichment of bacterial small ORF-encoded polypeptides (SEPs). Further, proteome-wide subcellular localization and protein stability studies will provide a dynamic view on bacterial protein expression.II) Bacterial proteoform interaction maps by the development of an innova
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Artificial quantum materials with photons: many-body physics and topology' (ARQADIA) under Horizon 2020.

assistant: **Objectives**

Physical systems featuring strong electronic correlations exhibit fascinating phenomena, as exemplified by high-Tc superconductivity, quantum magnetism or fractional quantum Hall physics. Inspired by these effects, new ideas have emerged to harness strongly correlated phases in artificial quantum materials, and use them as a resource for fundamental science and for quantum technology. Promising approaches for producing quantum devices are found in condensed matter platforms: one can indeed benefit from nanofabrication to engineer systems that are compact, versatile, and which can potentially be integrated in large-scale architectures. The main goal of ARQADIA is to engineer and study quantum correlated and topological phases of light using artificial photonic materials that I will fabricate in a solid-state platform. I will use exciton-polaritons in semiconductor microcavities, which are hybrid quasiparticles resulting from strong coupling between cavity photons and quantum well excitons. Polaritons are particularly attractive since they combine the best of two worlds: (i) through their photon component, they can be confined in microstrucutres and manipulated using optical spectroscopy; (ii) through their matter component, interactions between polaritons can be tuned and reinforced. Moreover, polaritons can be detected through the decay of cavity photons, which means that they naturally implement out-of-equilibrium physics and allow addressing fascinating questions related to the interplay between quantum correlations and dissipation. Within ARQADIA, I will tackle the challenge of engineering quantum correlations between polaritons via a technological breakthrough: I will insert active materials featuring strongly interacting excitons in microcavity lattices. I will use
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Recovery of nutrients from agricultural residues and improved dewatering through ultrasound technology'.

assistant: **Objectives**

European livestock holders and biogas plant operators produce billions of cubic metres of manure and digestate every year that need to be disposed. The disposal of these nutrient-rich suspensions on agricultural fields is restricted by the EU’s Nitrates Directive and derived national laws. Therefore, livestock holders and biogas plant operators cannot dispose their residues in this traditional way and have to pay much money for a third-party disposal.Weber Entec Entec GmbH & Co. KG, a German SME specialised in the development of innovative products based on ultrasound technology in the field of environmental engineering, has developed a new procedure for the treatment of manure, digestate and other organic suspensions which not only enables their disposal but also their valorisation. The substances will be separated into their solid and liquid compounds while the majority of the nutrients will be bound to the solid product. The liquid product can then be disposed without any restrictions, while the nutrient-enriched solid product can be pelletised and sold as a valuable storable organic fertiliser. A series of tests on the lab-scale has confirmed the proper functioning and the great potentials of the new technology. However, an industrial-scale technical prototype did not fully reach the same efficiency. Further research is necessary to develop a marketable product. In this proposed project, the technical feasibility of the necessary developments will be assessed and a business plan will be developed for the commercialisation of the machine.The ultrasound machine will help European livestock holders and biogas plant operators to not only save money for the disposal of their residues but also to generate an additional income by valorising and selling them. At the same ti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Interacting quantum field theory on gravitational backgrounds'.

assistant: **Innovation**

The unification of gravity and quantum physics is one of the main challenges of modern physics. A first step toward this aim would be the construction of interacting quantum field theories (QFT) on fixed classical gravitational backgrounds. Recently, in collaboration with Prof. K. Fredenhagen and Dr. M. Kohler, we stated what we call the 'microlocal spectrum condition' for selecting physical states. The condition is not empty since quasi-free Hadamard states satisfy it and with its use we proved, for the first time in this field, that the Wick polynomials of free fields are Wightman fields. In QFT on flat spaces several perturbative schemes have been developed and we follow now that of Epstein and Glaser. They construct and rigourously prove that each term of the perturbation series exists and fulfils locality, the main first principle of QFT. Our proposal is to generalize Epstein and Glaser scheme to curved space-times. Some preliminary attempts seem to indicate that our aim is reasonable since even for manifolds some of the steps in Epstein and Glaser work can be defined. In fact we are planning to use our previous work which ensures the existence of Wick polynomials and deals correctly with the spectrum condition on manifolds. However, several points are yet to be checked. Whence the existence of a renormalized perturbation theory is established, local renormalization conditions have to be found which fix the finite renormalization. Effects of curvature on observables quantities might be estimated and compared to esperiments.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Evolving landscape of neuroendocrine tumor disease: Predicting tumor behaviour using metabolic profiling' (2007-2013) targeting Seventh Framework.

assistant: **Abstract**

Background: Tumors that arise from neuroendocrine cells (NENs) were traditionally considered rare tumors with low malignant potential. Recent data suggest that the incidence of NENs has increased over the last three decades. Furthermore, symptoms are frequently overlooked and subsequently, 60-80% of these tumors present with metastases at initial diagnosis. The common denominator of these tumors is their neuroendocrine origin; however, they demonstrate remarkable diversity, unique properties and different survival rates. We have little knowledge regarding the fundamental regulators of proliferation of these tumors and, hence, we have a narrow range of treatment options. We need additional biological and molecular data to enhance our knowledge on NENs, optimize patient stratification according to prognosis and to develop a more successful treatment strategy. Metabonomics is an emerging research field that provides an insight into the metabolic pathways of living cells. It represents a promising tool for better understanding of genetic data, for establishing a “metabolic signature” and for interpreting epidemiology in the cell level by metabolic screening.Aim: The aim of this study is to develop a metabolic signature of NENs that would allow stratification according to the primary tumor site and the malignant potential. We will also try to investigate the reported increase of NENs incidence.Methods: Patients with neuroendocrine tumors will be included in the study. Spectroscopy and spectrometry techniques will be used for the development of a metabonomic profile.Relevance to the work programme: This project will allow the experienced researcher to attain a higher level of training in the management of NENs and to be exposed to the field of metabonomics. The expected impac
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Prevention, information and early warning pre-operational services to support the management of risks' (PREVIEW).

assistant: **Innovation**

PREVIEW proposes to develop, at the European scale, new or enhanced information services for risk the management in support of Civil Protection Units and local or regional authorities, making the best use of the most advanced research and technology outcomes in Earth Observation. Services will be validated under pre-operational conditions.The risks may result from the direct impact of atmospheric events, from their hydrological consequences or from geophysical events and in some cases be worsened or directly caused by industrial activities. The challenging issue is to enhance risk mitigation through better prevention, better anticipation and more accurate assessment at various time and spatial scales of situations at risk, improved timely dissemination of meaningful and adapted early warning information, fitted to the societal needs and to the operations of rescue forces. This has to be done in a joint effort of all actors and citizens to develop risk awareness and culture.The main axe of development through PREVIEW is: Improvement of the services contents: quality and harmonisation of the information services supporting the decision making at the operational level, improving information collection, aggregation and intelligence methodologies, developing synergies, cooperative work and inter-operability capacities among operators for a widespread application of the best solutions at national, regional, and European scale.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Building a European strategic Research and Innovation Area in Direct Synergy with EU and International Initiatives for Pandemic Preparedness' (2021-2027).

assistant: **Innovation**

The COVID-19 pandemic has confirmed and further highlighted the importance of planning and investing in research and innovation well before a health crisis occurs. For this purpose, the main goal of BE READY is to build a consolidated European Research and Innovation Area that provides the foundation of the candidate European partnership for pandemic preparedness so to improve the EU's preparedness to predict and respond to emerging health threats by better coordinating funding for research and innovation at EU, national (and regional) level towards common objectives and an agreed Strategic Research and Innovation Agenda. The Partnership is expected to build on existing pandemic preparedness networks, and work in synergy with the Health Emergency Response Authority (HERA), in close collaboration with ECDC, EMA and other relevant international and European actors. BE READY is composed by 24 organisations from 15 countries with complementary expertise and policy area ranging from Public Health Organisations, Ministries (of Science, University, Health, Innovation or Environment) and Research Performing Organisations that ensures a cross-cutting, interdisciplinary Global Health and One Health approach.


**Keywords:** pandemic, preparedeness, engagement, SRIA, one health, research and health technology
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Online Communication Analysis: Methods for Multimodal, Networked Communication' (OnCoA) under Seventh Framework.

assistant: **Objectives**

The overarching objective of the proposed project “Online Communication Analysis: Methods for Multimodal, Networked Communication” (OnCoA) is to develop an interdisciplinary methodological and theoretical approach to online communication in the field of media and communication studies that aims to provide applicable solutions for current and future demands in digital media and communication analysis.The term ‘online communication’ comprises here any communicative interaction/action on and by means of the Internet. Therefore, the project focuses on methods and underlying theories/paradigms regarding the analysis of multimodal, networked online communication where text, audio, pictures and video represent different albeit joined linguistic modes that build coherent content. Hyperlinks represent another linguistic mode that turns static and linear text into dynamic networked communication where both the text producers and readers become interchangeable actors.The innovative nature of the project lies in its interdisciplinarity, aiming at an integration of both social sciences-driven and media informatics-driven approaches in online communication research. The methodological, theoretical, and technological challenges of this research arise out of the multimodal nature of digital communication (e.g. websites or weblogs with text, audio, and video content). Additionally, the multitude and networked (i.e. hyperlinked) nature of online communication demand a revision and amplification of existing approaches to online communication analysis, specifically regarding the traditional methods in social sciences, such as content analysis.