RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Characterisation of molecules regulating adult hippocampal neurogenesis' in the context of a Seventh Framework call.

assistant: **Objectives**

The hippocampus contains a population of stem cells that continually proliferate to produce new neurons. The development of new markers capable of identifying and isolating defined neural stem cell populations are of utmost importance. Prominin-1 has successfully been used as a marker for the isolation of neural stem and progenitor cells from other brain regions including the mouse embryonic forebrain, the adult SVZ and the postnatal cerebellum. However, its potential as a marker of stem cells in the adult hippocampus remains to be confirmed. The first aim of this proposal is to examine the efficacy of Prominin-1 as a potential marker for the isolation and characterisation of hippocampal stem cells.We have recently discovered a dormant or latent population of neural precursors in the adult hippocampus that can be triggered to generate new neurons. Identification and characterisation of the molecules that trigger these latent neural precursors to generate new neurons should lead to the development of radical new therapies to treat neurodegenerative conditions that affect the hippocampus. Two candidate molecules (Prominin-2 and AP2-gamma) have been chosen based on preliminary microarray data and will be examined for their ability stimulate hippocampal neurogenesis.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Previz for On-set Production - Adaptive Realtime Tracking' (POPART).

assistant: **Concept**

European film makers are well-known for their creative innovation in selecting themes, their original way of storytelling and their art of cinematography. Like elsewhere in the world, they use computer-generated visual effects to achieve the intended visual experience and quality.To achieve the best interaction between the creative team on set and the post-production team, it is important to achieve the best common understanding between the team filming real scenes and the team working on visual effects. For this, previz has been developed. Previz today contributes to film making from the planning stage to filming with actors on set, where the final composition of mixed reality scenes can be reviewed during and right after the shoot.Large film studios that produce films with the highest budgets take the final step and integrate previz with the final post-production. For this, they develop in-house tools or cooperate with a company that is dedicated to the previz concept. This integration remains unavailable to most film makers and provides a strong competitive advantage. Without the integration, a gap remains between the team filming real scenes and the team working on visual effects in post-production.POPART will introduce an affordable and highly customizable solution that will disrupt the market and overcome this lack of competition. It will democratize the access to a complete previz solution integrated into the pipeline from shooting preparation to post-production, that doesn’t exist on the market. In contrast to the market lock-in solutions, all core elements required for real-time previz will be released in open source and will be based on open standards to provide an highly customizable solution.The product released by POPART will comprise hard- and software com
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Evaluation and certification schemes for security products – Capability Project'.

assistant: **Innovation**

CRISP aims at facilitating a harmonised playing field for the European security industry by developing a robust methodology for security product certification. CRISP will enhance existing security evaluation and certification schemes by offering an innovative evaluation methodology that integrates the security, trust, efficiency and freedom infringement assessment dimensions. The proposed scheme will be based on a taxonomy encompassing a variety of security products and services across applications, will take into account the varying roles of a diverse stakeholder community including manufacturers, regulatory and certification bodies, data protection authorities and end users and engage with each group to gather insights to help avoid acceptance problems that challenge current schemes.WP1 will create a taxonomy of security products and systems, concepts of operations, application areas, performance and set out criteria for comparing security products and systems. WP2 will provide an historical perspective on security standards and certification in Europe and analyse the state of the art in security standards, certification and accreditation at the Member State, regional and international level. WP3 will identify and determine the role of different stakeholders, gauge their views on the challenges affecting security certification and determine requirements for a harmonised EU-wide approach. WP4 will examine the core dimensions (such as security, trust, efficiency, freedom infringement) of security product certification and present the requirements for enhancing existing evaluation and certification schemes. WP5 will present a certification methodology, policy and procedures for security products, test-drive, evaluate and refine it. WP6 will present a roadmap for adopting
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'A Chemical Approach to Lead-free Nanosolders'.

assistant: **Objectives**

Physical, electronic and thermodynamic properties of small particles (nano-particles) differ significantly from those of the bulk materials, and the depression of the melting temperature below the melting point of the bulk has been known for a long time. This dependence of the melting temperature on the particle size is not restricted to any particular material and may therefore also be exploited to lower the melting temperatures of lead-free solders. At the same time, the high-temperature solders currently in use (melting temperatures 250-400°C) contain high amounts of lead and are exempt from the European RoHS directive due to reliability reasons. In the search for lead-free substitutes, Sn-Sb and Sn-Sb-M alloys have been identified as possible candidates. With the envisaged reduction of the grain size into the nanometer range and a corresponding lowering of the melting temperature, considerable energy savings would become possible in the first soldering step without sacrificing the stability of the obtained solder junctions against re-melting in the further assembling procedure. Therefore it is proposed to prepare micro- and nanosized particles of lead-free high-temperature solder materials, based on Sn-Sb-M (M=Ag, Cu, Ni) from suitable chemical precursors. These precursors will be prepared by precipitation reactions, followed by thermal decomposition and, if necessary, by adequate reduction reactions, and the reaction conditions will be optimized. The particles will be characterized by chemical analysis, SEM and TEM, and by thermo-analytical methods, and the corresponding properties will be compared with those of bulk materials. At the same time, additional experiments in the bulk systems Sn-Sb-Ag and Sn-Sb-Cu will be performed to complete the available literature i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'On-chip optical communication with transformation optics' under Horizon 2020.

assistant: **Concept**

Transformation optics grew out of ideas for invisibility cloaking and exploits connections between electromagnetism in media and in geometries. This Proof of Concept project uses transformation optics for improving on-chip optical communication in silicon photonics. The goal is reaching a performance that matches industry standards such that the idea becomes sufficiently convincing to be commercialized.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The targeting and biosynthesis of membrane and secretory proteins' (MEMPROT-NET) under Fifth Framework.

assistant: **Objectives**

Our objective is to - provide a detailed understanding of the biosynthesis of membrane and secretary proteins. The focus will be: 1) components 2) molecular mechanisms and 3) regulation. A detailed molecular understanding of these key issues is currently lacking. Furthermore, although membrane protein biosynthesises directly relevant to exploiting the cell factory, little effort has been made to establish whether this process can be engineered. We will achieve our objectively focusing the research efforts of individual teams into a co-ordinated research programme. The teams provide several different biological systems, enabling information and technology transfer, and represent all of the disciplines crucial to the project: biochemistry; cell biology; microbiology; structural biology; biocomputing and commercial exploitation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Development of PEM Fuel Cell Stack Reference Test Procedures for Industry'.

assistant: **Innovation**

In this project proposal, industry wide harmonized test procedures for PEFC stacks shall be developed and validated. The proposal builds on experiences gained in the FCTESTNET, FCSTEQA series of projects taking up the methodology developed there and expanding it to the test of PEFC stacks. Furthermore, experiences of individual consortium members have long time experience in international standardization. Performance / functional, durability and safety outputs for vehicle propulsion, stationary and portable applications shall be addressed.Generic test modules addressing the effects of outputs to the variation of a single test parameter shall be defined and experimentally validated on a stack level. From these building blocks, selected application oriented test programs shall be derived and validated as well. A two phase approach is pursued starting with an initial selection and definition phase followed by experimental validation. Subsequently, a review is carried out followed by a second validation phase.The consortium mainly consists of experienced research organizations, all working in close contact with and providing testing services to industry. The test modules and test programs are expected to be methodologically sound and independent. Contact to industrial practice will be established by the implementation of an industrial advisory group consisting of selected key stakeholders along the value chain of the fuel cell industry. The consortium will liaise with international standardization activities and contribute to the improvement of existing standards by pre-normative research and – if deemed necessary – initiate new work item proposals on performance and endurance testing of PEFC stacks.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Coupled cluster theory for polaritons: changing molecular properties with quantum light' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The chemistry of light-matter states (polaritonic chemistry) is a relatively new research area in chemistry. Recent experiments have demonstrated that molecular polaritons can have a profound impact on the outcome of chemical reactions taking place inside cavities. Molecular polaritons are formed when the molecular degrees of freedom couple strongly with the modes of a quantum field. From a theoretical point of view the experiments are highly complex, with many different interactions taking place, and a detailed theoretical understanding of the observations is still uncertain. The mission of QuantumLight is to explore, using advanced theoretical modeling, the phenomena that arise when quantum fields interact with molecules and the possibilities that emerge for chemistry. Detailed theoretical and computational understanding of these phenomena will open completely new ways to control and manipulate molecular systems and study new states of matter. The theoretical foundation is cavity quantum electrodynamics (QED), and it will, when combined with the methodologies of quantum chemistry, enable a predictive computational framework for interpretation and future design of polaritonic chemistry. The QuantumLight project will develop and apply  accurate electronic structure methods for molecules interacting with quantum fields, in particular coupled cluster theory. Different types of quantum fields will be studied, focusing on those that appear inside optical cavities and the surface plasmon polariton field that is formed by metallic nanoparticles and nanogaps. Applications of the methodology will include ultrafast dynamics in photochemistry, molecules in chiral cavities, electron-photon dynamics, X-ray spectroscopy in cavities, and polariton-assisted chemical reactions.


**Key
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Adaptive optics for retinal imaging and improved vision' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Adaptive optics has proved to be extremely successful in astronomy, providing diffraction limited imaging for ground based telescopes in the 8-10 metre class. The overall aim of this project to apply the technique of adaptive optics to high-resolution imaging of the retina and to providing improved vision. By apply adaptive optics to retinal imaging, it will be possible to image the photoreceptor mosaic on the scale of a few microns, and this will be of significant clinical value for the early detection and monitoring of retinal degeneration, for example due to age-related macular degeneration There is also the possibility of stimulating single photoreceptors, or small groups of photoreceptors, thus allowing novel experiments and investigations in visual perception. Our objectives will be achieved through five inter-related work packages:1. Imaging the retina2. Clinical applications3. Improving vision4. Wave front sensing5. Eye and tissue properties The participating groups (7 from 5 countries) have backgrounds related to adaptive optics in astronomy (ICSTM, LESIA and TECH) and in clinical ophthalmic optics and vision science (IOO, LBV, LOUM and VEIC), representing a well-balanced, and highly qualified, team for this project. As a result of this project, we expect to achieve diffraction-limited imaging of the retina in a clinical setting (as opposed to lab-based), and to have implemented adaptive optics that provides improved visual acuity. The project provides the opportunity for cross linking between researchers primarily based in physics and astronomy and those primarily based in the life sciences and medic me, The young scientists will work across these fields and gain experience in the approaches used in interdisciplinary research.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'COMBATING RESISTANCE TO ANTIBIOTICS'.

assistant: **Objectives**

Combating bacteria with antibiotics is an endless race because bacteria acquire antibiotic resistance (AR) genes easily from unknown environmental sources. Until now, understanding and control of AR spread was attempted through the precise descriptions of AR genes presently found in hospitals, and inference from this of the working mechanisms of dispersion (epidemiological approach). We think that an appropriate long-term public health objective would be to elucidate the molecular mechanisms behind the observed AR spread in a concerted strategy targeting the dissemination modules, from AR recruitment to their ultimate acquisition by bacterial pathogens. Thus, the focus of this project is to explore a mechanistic approach to combat AR. A coherent picture, which could explain the road to multiple AR in gram-negative species, is beginning to emerge from research on gene mobility. Starting from the superintegrons, which could be considered as the cradles" of many AR, integron cassettes are recruited into integron platforms carried by transposons or plasmids. Insertion sequences (IS) capture genes or integron platforms to form transposons, which are subsequently translocated to conjugative plasmids. Plasmids transfer AR and establish themselves with variable efficiency in pathogenic bacteria. Finally, plasmids need to be stably inherited once they established themselves in a recipient cell. Specific mechanisms ensure that plasmid-free cells are eliminated. The objectives of CRAB deal with each of the dissemination modules in this chain ' integrons (WP1), transposons (WP2), conjugative plasmids (WP3) and stability modules (WP4) ' in a concerted approach. We concentrate on the as yet improperly studied aspects of these mechanisms. WP1: mechanism of integron cassette recombinat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'The evolution of cancer in ageing societies: An international perspective'.

assistant: **Innovation**

This project is a training-through-research project that aims to describe the global evolution of cancer in the ageing societies using international comparison studies. Three theories have been proposed to explain the dynamics of ageing populations: compression of morbidity, expansion of morbidity, and dynamic equilibrium. Yet, these theories have never been applied to understand the evolution of cancer, a disease that occurs primarily at old age. Using global databases, I will assess the population impact of changes in longevity and duration of morbidity among patients with cancer. I hypothesize that increases in life expectancy after cancer diagnosis have primarily led to expansion (longer time spent with disease before death) rather than compression of years lived with illness and disability. Life table analysis weighted for severity of cancer types to derive disability-adjusted life expectancy will be used to assess the evolution of cancer in ageing societies. This is the first study to apply the dynamics of aging population theories to unravel how cohort of cancer patients can be expected to evolve after survival. The study will also provide an important base for applying these theories in the aging theories in general and to solve health care issues pertinent to this frail population.Parallel to the scientific activities aimed to describe the dynamic of ageing among cancer patients, this project will provide various training opportunities to increase my competence in analysing large databases, in communication and teaching, in writing scientific articles and it will also substantially increase my collaborative network. The combination of renowned scholars with the available resources and access to international networks makes the host institution (International Ag