RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Giant Organic Magnetoresistance BioSensing' in the context of a Seventh Framework call.

assistant: **Objectives**

The GOMBS project prepares the commercialization of ultrasensitive point-of-care biosensors for early-stage detection of life-threatening diseases, based on the largest MR effect ever observed at room temperature and small magnetic fields, recently discovered by the PI [Science 341, 257 (2013)]. Target biomolecules are specifically attached to the sensor and magnetic nanoparticle (NP) labels, and electrically detected using this huge MR effect (patent in preparation). We will develop sensors for disease markers such as prostate-specific antigen (prostate cancer), troponin (heart muscle damage) and hypermethylated DNA (several cancers). The PI will make use of his long-standing, fruitful collaborations with organic chemists on magnetic NP synthesis and assembly, and functional organic monolayers. As the most competitive advantages of our sensor technology we identify (1) high selectivity, sensitivity and speed (2) very simple, scalable device concept, (3) robustness against environmental fluctuations (e.g. temperature-, pH-independent), (4) small size (allowing implementation in a bioassay device for multiple target molecules), and (5) low cost price.Recognizing commercial potential and a clear market need, the GOMBS team is highly motivated to start up a new venture for exploitation of the proposed biosensor. We will develop the optimal business strategy with an experienced business executive. We will collect market insights for calculating the feasibility, and for setting up a strategic mode of action. In collaboration with a patent attorney a strategy will be defined that secures IP protection. GOMBS will deliver a technical proof of concept and a comprehensive business plan including presentation of the product and concept, the team, business and IP strategy, busines
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'NANOMATERIALS ENABLING SMART ENERGY HARVESTING FOR NEXT-GENERATION INTERNET-OF-THINGS' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The 4th Industrial Revolution (4IR) builds on the Internet-of-Things (IoT) paradigm, as it relies upon the scenario of having billions of interconnected autonomous mobile devices, with unprecedented processing power, storage capacity and access to knowledge. While enabling such massive deployment, the 4IR should be increasingly eco-friendly. The 4IR is a disrupting approach that will force companies in almost every domain to re-organize themselves in a more efficient way, by exploiting technological breakthroughs such us artificial intelligence , wireless communication and quantum computing. The integration of these emerging technologies into every day life requires efficient power supply solutions in computing, sensing, memory enlargement and human-machine interaction. One perceived bottleneck for 4IR is that in most situations, IoT devices/networks will be remotely deployed, so that maintenance may be either incovenient or impossible. In particular, this implies that IoT devices either have to embed energy sources consistent with their operative lifespan or that clean and renewable energy convertors, if working off-grid, must sit on board. The significant broadening of the wireless communication spectrum in Europe makes the Radio frequency (RF) energy scavenging a highly desirable way forward for clean powering of the next-generation IoT.NANO-EH has the ambitious vision of creating a pathway for translating forefront knowledge of unique high frequency properties of emerging classes of nanomaterials into advanced device engineering for scalable miniaturized energy harvesting/storage submodules that are tailored for the specific needs of  stand-alone, mobile or portable uses. It surpasses the current paradigm of energy harvesting materials by developing non-toxic and ra
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'A mathematical platform for Abdominal Aortic Aneurism risk assessment and surgical planning' under Horizon 2020.

assistant: **Concept**

Abdominal Aneurysm of the Aorta (AAA) is a degenerative disease of the last segment of the abdominal aorta, representing the 14th leading cause of death for the 60 to 85 year-old age group in US. An estimated 80 million people aged 60 years and older are at risk in Western Europe. To date the most commonly used clinical protocol for surgical acceptance is based on the estimate of  AAA diameter.  The report prepared for the Agency for Healthcare Research and Quality came to the conclusion that: the annual risk of rupture is 1% or lower for a diameter less than 5.5 cm; the 1-year risk of rupture increases with the aneurysm size; it may exceed 10% in the individuals with diameters above 6 cm.Assessment of AAA rupture risk has long been a topic of interest in clinical research setting. The ability to estimate patient specific probability of AAA rupture can lead to reduced health care costs, adequate and timely patient diagnostic and comfort.Math4AAArisk aims at the realization of a mathematical platform to support clinicians through the following steps: (A1) From medical imaging to sizing and morphological characterization of AAA, (A2) Preliminary risk evaluation, (A3) Computer simulation and enhanced risk assessment, (B1) Automatic surgery planner, (C1) Anonymous data base storage.The proposed mathematical platform yields quantitative physical indicators in real time at the sole request of inputting a few clinical measurements; it is patient adapted, as it integrates with patient’s radiological images, under full control of clinicians; it is aimed at improving the diagnostic analysis and possibly the surgical planning.  We wish to establish the viability for a market exploitation of the math4AAArisk platform and identify possible later stage funding opportunities.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Tibetan Book Evolution and Technology' to be submitted under Seventh Framework.

assistant: **Abstract**

Worldwide interest in books as artefacts and ritual objects has raised new questions as digital technology is radically transforming book production and circulation. What is a book? Can it be really reduced to its content and therefore easily made obsolete by more efficient mediums of communication? How does a culture-specific understanding of the book as object relate to technological innovation? This project will contribute to the broad cross-cultural debate by looking at books in the Tibetan context, where its civilization has considered literary artefacts as crucial throughout its history and has developed appropriate technologies over the centuries. The research will focus on printing as a technological innovation that developed fairly rapidly in Tibet in the 14th–15th centuries and remains little documented and understood as a process involving technical, economic, political and religious factors.The proposed research spans a range of different disciplines, including Tibetology, philology, codicology, history, anthropology, chemistry, geography, archaeology and art history. It has three interconnected aims, to: 1) assemble and study early Tibetan prints from South Western Tibet by using new technologies and methods, 2) understand Tibetan book production and use in its historical and cultural context, 3) explore the relevance of Tibetan technological innovation for cross-cultural questions inspired by work on the ‘printing press’ as an agent of change in European history and by Roger Chartier’s call for the study of xylography within the wider exploration of technological innovation in communication.The research will reach beyond academia by being reflected in a public exhibition of Tibetan books as literary artefacts and by facilitating the digital repatriation of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Quantifying Aerosol Nanoparticle Dynamics by High Time Resolution Experiments' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The formation of aerosol nanoparticles by vapour nucleation and condensational growth is currently considered the dominant source of cloud condensation nuclei on global scale, hence impacting radiative properties of the atmosphere and precipitation patterns of clouds. Despite considerable experimental and theoretical efforts, the mechanisms of the gas-to-particle conversion are still poorly understood, and so are the parameterizations of this process in climate models. Improving the situation critically depends on the continuous development of experimental techniques. For the quantitative characterization of nanoparticle dynamics especially time resolution deserves more attention. I am thus proposing to design instruments that will improve time resolution by up to five orders of magnitude. Specifically, I am planning the design of a fast-scanning electrical mobility based nanoparticle spectrometer delivering size distributions from 1 nm upwards at 1 Hz, for number concentrations as low as 100 cm-3. Secondly, in a new approach to the study of secondary organic aerosol formation I am planning to apply small angle x-ray scattering providing direct information on particle size and number at sub-millisecond time-resolution. Thirdly, the study of fundamental growth kinetics by Mie scattering at short wavelengths will constitute an important part of my research. And finally, an application oriented research task will deal with the design and construction of a nucleation based trace-gas removal system capable of generating liquid water from plain ambient air.The research on phase transition processes constitutes a vital link between molecular scale interactions and macroscopically relevant outcome. The current proposal aims at identifying and quantifying nanoparticle formation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'My Science - Our Science' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The impact of researchers’ work on society and citizens has never been more apparent than now. At the same time, there is an impending risk of loosing citizens’ trust in science, due to incresed amount of misinformation about science and research. Therefore, it is important to promote the key role that researchers have for the development and growth of our societies in a national and international context, and for keeping the public informed about critical challenges and scientific discoveries that have an impact on our daily lives. In Iceland, science has a crucial role to play in a society that relies to a great extent on nature and responsible use of natural resources, from renewable energy and sustainable blue growth to the societal and cultural implications of living in coastal communites. In order to ensure and facilitate interaction with the public and society at large, the project ""My Science – Our Science"" aims to organise European Researchers Night in Iceland with the aim to invite researchers to engage with the public to communicate their work, their passion and their findings in order to increase the awareness of research and innovation activities. The objective is to enhance a positive public perception of researchers by facilitiating an open and active dialogue between researchers and citizens of all ages, especially focusing on children and young people that could consider a research career. In addition to higlighting the importance of researchers’ work, the initiative provides a rare opportunity for researchers to communicate directly with the public at all ages and even to involve citizens in the road to scientific discoveries, thus contributing to the transparency of their work and enhancing the attractiveness of scientific careers, which is instrume
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Initiative on Optimizing Malaria Vaccine Lab Assays Evaluation' (OPTIMALVAC).

assistant: **Innovation**

A broad-range of candidate malaria vaccines derived from diverse novel technologies have resulted from the multiple approaches being taken by different groups in developing malaria vaccines. The majority of the candidates are recombinant proteins based on complex native antigens found on the surface of the parasite. Vaccine potential of these parasite surface antigens is often supported by epidemiological data, and by the ability to induce specific antibodies or potential protective responses in animals and later, in humans. Individual groups have developed assays within the context of the vaccine discovery efforts, with identification of measurable processes for parasite growth and virulence to test specific antigens. In-house assays are strain, stage and even process specific and the ability to compare results between different candidates is further limited by diverse methodologies and assay components such as parasites, cells and reagents. The absence of some level of harmonization of practices also makes interpreting the meaning and relevance of vaccine research outcomes complex. Lack of an enabling environment for comparability of research results generated in different labs could unfortunately lead to scepticism of the results that in turn generate uncertainty about the efficacy of the vaccines and rationale of the development pathway. To compare the relative merits of different candidate vaccines and approaches in a credible and informed manner, efforts must be made to create this enabling environment by supporting the development of a baseline level of standardization around key assays that can be utilized a) in the evaluation of malaria vaccines, and b) throughout the Development process. Consistent, reproducible and comparable intra- and inter-lab performance
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'EXpanding Platforms for Efficacious mRNA Therapeutics'.

assistant: **Concept**

The overall objective of EXPERT is to create an off-the-shelf mRNA-delivering nanomedicine platform that is manufactured via a quality-by-design (QbD) approach with precise nanoparticle characterization and specifications that meet the requirements for GMP scaling up and clinical translation. As proof-of-concept we will perform a first-in-man clinical study for an intratumorally administered immunostimulatory mRNA-nanomedicine in cancer patients. The work focuses on the three critical elements of the call “Innovation platforms for advanced therapies of the future”  1. EXPERT investigates mRNAs as therapeutics, which are classified as advanced therapies. 2. By showing proof-of-concept in a clinical trial we aim to meet the technical, industrial and regulatory challenges to develop a mRNA-nanomedicine formulation from bench to bedside. This opens up new treatment possibilities for a large group of cancer patients and paves the way for subsequent formulations strengthening the European advanced therapy R&D. 3. mRNA nanomedicines are a true platform technology. mRNAs are composed of four similar building blocks, resulting in a molecule with predictable qualities. This allows for a platform approach to production, purification, formulation and storage which streamlines the drug development process offering important technological progress in this field. We will encapsulate mRNA into nanocarriers. Thereby, the mRNA is protected and the physicochemical characteristics of the mRNA are overruled by the characteristics of the nanoparticle to enable target cell uptake. We have experience in state-of-the art materials to make mRNA nanomedicines. To address their complexity we will optimize nanoparticle design and manufacture via QbD. We will use microfluidic manufacture as a scalab
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Personified Self Interaction' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

This proof of concept is based on the ERC Advanced Grant TRAVERSE (2009-2015). It will exploit immersive virtual reality in a new form of psychological clinical intervention akin to Gestalt Therapy.  The primary aim of this Proof of Concept project is to generate a business model that would allow us to diffuse our technology to thousands of counsellors and psychologists around the world. In order to accomplish that we commission further trials to extend the evidence base of the approach, investigate through market research the extension of the technique for business practice, develop a commercial prototype with consumer equipment that would be low cost but high quality, exhibit our product at international conferences, and make the system available on loan to psychologists or counsellors who wished to try it, and generally start the process of diffusion. Moreover, we that our low cost system incorporates patentable inventions that would be investigated in an IP strategy. Through this approach we will develop the Business Model and a draft Business Plan for mass take up of our applications.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Models of Soil Hydraulic Properties with Adjustable Soil Structure and their Application in an Earth-system Model'.

assistant: **Innovation**

The spatial arrangement of solids and pore spaces within soil (soil structure) is a major source of variability in the hydraulic properties of soils. It is through changes in soil structure that biological activity, land management, or the passage of time (including wet-dry and freeze-thaw cycles) affect the capacity of soil to retain and conduct moisture. Nevertheless, soil structure is at most tentatively represented in Earth-system models. As a result, we cannot quantify the effect of biological activity and management on soil water content and thus their full effect on the regional climate or the land carbon sink. This represents an important gap in our understanding of the natural environment, as well as a potential blind spot in our response to the climate emergency. Including soil structure in land-surface models is difficult, because its effect on the soil hydraulic properties cannot be reliably predicted based on a single, easy-to-measure quantity such as bulk density. At the same time, more detailed soil structure data and the methods to incorporate it are largely missing. MOSS will address these issues by 1)~developing a physics-based method of incorporating beyond-density soil structure information into the models of soil hydraulic properties, 2)~implementing this method in a state-of-the-art Earth-system model, and 3)~using the new model to quantify the impact of soil structure on the land carbon sink. By doing so, MOSS will likely demonstrate that soil structure must be included in numerical models and protected in the field. Moreover, the method developed by MOSS will be applicable to agronomical and hydrological models and thus will have a plausible impact on the socially and economically important policy decisions these models inform. Finally, because o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Strengthening Research in Armenia for Energy Transition toward Climate Solutions' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

A key tenet of the European Green Deal (EGD) is to build clean and renewable energy capacity as a key step toward decarbonisation while providing energy security. Planning and implementing the transition to a decarbonized, sustainable, and resilient energy regime is a complex technical, social, political, and economic process. In the case of Armenia, its landlocked and tense geopolitical position in the South Caucasus adds to the complexity of its energy transition efforts. STREACS aims to enhance the research capacity in Armenia to support the country’s efforts to accelerate its energy transition toward clean and renewable energy sources, while enhancing its energy security. Importantly, such enhanced capacity will also enable Armenia to become better integrated into and a more productive actor in the European Research Area. STREACS will facilitate the transfer of knowledge, exchange of best practices, and inclusion in domain-specific academic networks from research institutions and partners in the EU.


**Keywords:** Energy transition, renewable energy, clean energy, climate change, European Green Deal, research excellence