RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Family formation decisions and gender attitudes in crisis times: an international, historical and longitudinal comparison.' (FAMilyDECisions).

assistant: **Concept**

During the last decades, Spain has experienced not only an strong decrease on its fertility levels but also a significant delay in its timing to childbearing, so much so that it has been considered one of the countries with the lowest-low and latest-late fertility in the world. This research aims to better understand the reasons behind young adults’ behaviors in family dynamics in a moment where it is possible to approach the impact of the economic crisis from different dimensions of the analysis. An extended scientific literature can be found about family formation dynamics and fertility, especially for European countries and mainly using a quantitative perspective. This mainly qualitative project proposes an innovative methodology to analyze the Spanish case from a three different perspectives of analysis: a cross-country comparison (five countries in 2012), an historical comparison (Spain 1985 vs. 2012) and a longitudinal comparison (Spain, same sample in 2012 and 2017). Furthermore, mixed methods will be applied considering the contextualization of qualitative data with quantitative data from census and surveys as complementary approaches; and the application of quantitative analysis to qualitative data. Main data from Spain in 2012 comes directly from the words of young adults in three different moments of their family formation decisions: i) to start a stable relationship; ii) to become parents; and iii) to expand the family after the first child. Main data consists of eighty (80) in-depth personal interviews already carried out to young adults between 24 and 35 years old, living in the Madrid and Barcelona metropolitan areas, that will be compared with an identical sample in the US, Sweden, Japan and Korea. Historical data comes from an existing comparable study
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Nanoplasmonic sensing of multi-molecular protein interactions at physiological conditions'.

assistant: **Concept**

I will develop a single-molecule sensor that reveals multi-protein dynamics at micromolar concentrations to provide new understanding of how protein machinery functions in real-time. Proteins and their interactions are the cornerstone of biological processes. The dynamic cooperation between multiple species is key to most processes including chaperone-mediated protein folding, signal transduction, and metabolism. The dynamics of these processes is fast and adaptive due to a tailored combination of low affinity and high concentration. Current single-molecule sensors cannot capture these dynamics because (1) they only work in dilute solutions which perturbs the dynamics or (2) they only resolve a single species. Capturing dynamics of protein machinery at physiological conditions therefore remains one of the grand challenges in the field. MultiSense will develop a nanoplasmonic sensor to provide the opportunity to reveal multi-molecular protein dynamics at micromolar concentrations. This will be achieved by (a) developing technology to resolve and interpret multi-protein interactions and cooperation using Förster Resonance Energy Transfer in the confined near-field of a plasmonic particle, and (b) using this technology to provide the first real-time picture of chaperone-mediated protein folding at physiological conditions. This will contribute to unraveling why chaperones fail to induce proper folding or prevent protein aggregation in the context of diseases. The proposed method can be implemented on any research-grade microscope and can be generalized to any protein by applying the proper particle functionalization. This will inspire other researchers to study dynamic cooperation in protein machinery to unravel complex molecular mechanisms. In the long term the small size
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Plug-and-produce COmponents and METhods for adaptive control of industrial robots enabling cost effective, high precision manufacturing in factories of the future' (COMET), addressing dissemination and exploitation.

assistant: **Impact**

Yesterday’s, today’s and tomorrow’s challenging and dynamic economic environment forces European high-end manufacturing industry to focus on high flexibility, high quality, reliability and low life-cycle costs and to respond quickly to changes in this environment. The high-end manufacturing industry requests production systems that can quickly switch between diverse machining operations with short changeover, programming and set-up times without compromising quality, reliability or life-cycle costs. From a conceptual point of view, industrial robot technology could provide an excellent base for machining being both flexible (due to their lay-out) and cost efficient (robots cost 2-5 times less then machine tools). However, industrial robots lack absolute positioning accuracy (1), are unable to react in real time to changing process conditions (2) and lack reliable programming and simulation tools to ensure first time right machining once production commences (3). These three critical limitations prevent industrial robots from being integrated in high-end machining processes. The COMET consortium will provide a revolutionary Plug-and-Produce solution enabling the use of industrial robots for high end machining processes, appreciating the needs from the manufacturing industry for cost effective, flexible and reliable manufacturing solutions. The proposed solution will be on the average 30% more cost effective than dedicated machine tools whilst delivering absolute positional accuracy of at least 50 µm. Due to the sense of urgency in Europe’s manufacturing industry the COMET consortium defined an ambitious work plan of only 30 months to develop and demonstrate the innovations planned and meet the objectives set. These ambitious goals and the planned dissemination and traini
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Virtual certification of acoustic performance for freight and passenger trains' in the context of a Seventh Framework call.

assistant: **Objectives**

ACOUTRAIN will simplify and improve the acoustic certification process of new rolling stock, in particular relating to the TSI Noise. Today the need of conformity assessment for a new vehicle according to the TSI Noise represents a significant element of both cost and time to market due to the need to carry out expensive and time consuming tests. The goal of the proposed project is to speed up the product authorisation by introducing some elements of virtual testing while retaining the same degree of reliability and accuracy. A successful simplification of the TSI conformity assessment process would result in a strengthening of the competitiveness of the European railway sector. The risk of not developing such a simplification would be that the expense of excessive certification of new products could hamper the introduction of new innovations.The major outcome of the ACOUTRAIN project will be a new certification process including some elements of virtual testing. This will be ready for inclusion in the next “full revision” of the TSI Noise, planned in 2013.The R&D work program will be implemented with the following objectives: WP1- establishment of procedures for a virtual certification of acoustic performances of freight and passenger trains; WP2 -an improvement and harmonization of the rolling noise characterization process; WP3 -establishment of methodologies to measure other noises sources; WP4 - a methodology to validate global tools for pass-by noise and standstill noise predictions so that they can be used as part of future certification; and WP5 -  a validation of the procedure range for the virtual noise certification. A significant part of the project is dedicated to the relationship with the Notify Bodies and Authorities to ensure that the objectives of the p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Soil MIcrobial responses to land use and climatic changes in the Light of Evolution' (SMILE) targeting Horizon 2020.

assistant: **Abstract**

Quoting T. Dobzhansky, “nothing in biology makes sense except in the light of evolution”. This idea could shed new light on how soil microbes access, transform, store, and release their most important resources – carbon and nutrients. We know that these microbial processes have global-scale impacts, including climate regulation and provision of nutrients to plants, but how microbes respond to changes in resources remains challenging to understand and quantify with models. In fact, current models cannot reliably reproduce carbon and nutrient storage and fluxes when soils are disturbed by land use changes or environmental fluctuations (especially of soil moisture). To address these urgent challenges and improve predictability of carbon and nutrient cycling, I propose a novel theory based on the premise that microbial use of soil resources is optimized by natural selection. This approach will provide a holistic explanation of microbial processes and yield models that are more reliable than traditional ones because they account for microbial adaptation. After testing this optimality hypothesis, I will answer the broader and globally relevant question – are land use and climatic changes increasing retention or loss of soil carbon and nutrients?The project will achieve four objectives:1)Determine the optimal strategies of resource use by soil microbes2)Fill knowledge gaps on microbial processes by constructing new databases3)Test the optimality theory using the new databases 4)Integrate the optimality theory into a land surface model to scale up results and assess impacts of land use and climatic (specifically hydrologic) changes on carbon and nutrient storage and fluxesThese theoretical advances will spur a new generation of soil models that translate the outcomes of natural
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'BioCHIPS - Biofabricated microfluidcs CHIPS based on self assembling of CNCs to recreate the hierarchical fibrillar structure of human tissues ECM' to be submitted under Horizon Europe.

assistant: **Abstract**

Biochips proposes an innovative bottom-up strategy to directly fabricate cell-laden devices that recreate the unique biophysical cues from the native fibrillar ECMs and allow the design of bioengineered microtissues with arbitrary geometries. The proposed platform combines the concepts of matrix-assisted 3D free-form bioprinting with the controlled self-assembly of colloidal cellulose nanocrystals (CNCs) to fabricate cell-laden constructs embedded within its own fibrillar CNC hydrogel device. The proposed platform can array multiple independent single organ models in a high-throughput manner (number will depend on the desired model complexity and well plate used) or link multiple tissue/organ models together with microfluidic circuits that can be user-defined on their CAD designs. The BioCHIPS system enables high-resolution printing of complex and perfusable multicellular constructs without separating membranes or plastic barriers, where cells can interact through signaling gradients created by compartmentalization in a bioinspired fibrillar matrix, and supporting their long-term culture. In addition to optical transparency for real time monitoring, CNCs hydrogels can be bioorthogonally digested to release the embedded constructs for post-bioprinting analysis and processing, which is a crucial advantage in organ/tissue-on-chip applications. Beyond the fabrication of perfusable microfluidic channels and cell-laden chambers for the development of 3D microphysiological systems as in vitro models, the intrinsic characteristics of this bioinspired platform, further enables its scale up to produce tissue engineered constructs within its own bioreactor for in vitro maturation and biological tests at higher scales.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'From materials science and engineering  to innovation for Europe.' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

M-ERA.NET will be a real tool for developing a strong European RTD community on materials science and engineering and for supporting the European economy with respect to the challenges of the 21st century.M-ERA.NET will be a highly ambitious network involving a majority of European key players in national funding of materials science and engineering.M-ERA.NET will replace a number of smaller previous ERA-NETs and cover the materials domain with an innovative and flexible umbrella concept for one single ERA-NET contract.M-ERA.NET will set up a multi-annual policy for joint programming targeted at the whole innovation cycle.Cooperation at an international level will enable the European RTD community to access world leading knowledge.It is our mission to- strengthen the status of the European RTD community and economy in materials sciences and engineering;- mobilise critical mass of national and regional funding for transnational RTD cooperation in materials science and engineering, thereby achieving a very large leverage effect of the requested FP7 funding;- set up a novel umberlla concept for cooperation to react to emerging needs and to allow coverage of future topics in related thematic areas;- establish strategic programming of joint activities, addressing societal and technological challenges in an interdisciplinary approach;- support the exploitation of created knowledge along the whole innovation chain;- enable enlarged research cooperation within the EU member states and associated states;- establish international cooperation with partners outside Europe;- exploit the novel developments in a durable, long term cooperation between funding organisations.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Developing New Strategies for the Production of Viable Hybrid Nanocrystals with Applicability in Energy Conversion and (Photo)catalysis.' (Photo) targeting Seventh Framework.

assistant: **Abstract**

The main objective of the 3 years research activity herein described is the design and development of protocols for the colloidal synthesis of a new generation of  multi-component hybrid nanocrystals (HNCs) with precisely tunable properties and applicability in energy conversion, (photo)catalysis and environmental remediation. In this context, MINE aboard the most problematic points related to the growth of multi-component materials, in particular the conditions by which it is possible to tune both, the materials that compose the structure and the morphology of the final structure (core-shell or oligomer-like configurations), by integrating the synthesis, the structural characterization and the study of NC properties. Among all the systems we will focus on the design and development of synthetic strategies for the production of metal-semiconductor, metal-semiconductor oxide and metal-metal oxide. The research activity has been divided in four different parts: i) the development of synthetic strategies for the production of multicomponent hybrid NCs, ii) the characterization and study of their physico-chemical properties, reactivity and structure-activity relationships iii) the study of their applicability and iv) the determination of their long-term use in terms of safety, sustainability and feasibility, a necessary step before promoting the ""real"" applications of these novel exciting nanostructures.We expect that results arising from MINE, will allow not only preparing new and long sought materials, but also re-designing many of the existing materials and recipes, and therefore moving the state of the art to the next step, which can be seen as the fifth-generation of NCs by design""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Memory dependent PAth Sampling methods for understanding long TIMEscale molecular processes' under Horizon Europe.

assistant: **Concept**

Time matters: timescales determine the fate, behavior and functionality of living matter. Especially the interplay between fast and slow molecular processes is omnipresent in biochemistry (protein folding, enzymatic conversions, molecular signaling, etc.). However, in chemistry, models are lacking to properly understand time and its effect on this difficult biological reality.PASTIME will lay the methodological foundations for a correct understanding of time in chemistry by introducing memory dependent transition interface path sampling to chemical modeling. We will tune the memory that is kept in simulations by creating new path ensemble definitions. The problem will be made computationally solvable by cutting molecules' pathways short. Long timescale effects will be studied through pathway statistics. We will achieve higher decorrelation in the sampling by designing new Monte Carlo moves in path space, such as alchemical moves that change the identity of atoms on the fly, and smart use of memory expansion with a replica exchange move. These new time concepts will be challenged and experimentally validated in a context of drug transport kinetics: drug (un)binding to protein binding sites, and permeation of molecules through cell membranes. The modeling principles will be converted to new algorithms that are computationally feasible today and will be shared in open software.With PASTIME we will be able to understand slow time effects in molecular interactions. Appropriate memory reduction and tuning will give us the methods to understand time in an endless range of molecular processes, and this work will contribute to drug design, biochemistry, physiology, catalysis, material and polymer science.


**Keywords:** molecular modeling, statistical physics, molecular dynamic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Development of Advanced Renewable Photocatalytic Hydrogen Generation Technology' in the context of a Seventh Framework call.

assistant: **Objectives**

The project is aimed at developing the nanoscience and technology required for efficient production of hydrogen fuels by using H2O and solar energy as sources. It is basically a laboratory based research work, which includes the design and development of hierarchical Schottky nanostructures (HSNs) and thereby Solar Fuel Cells (SFC) for hydrogen fuels. Today, the realization of technology to harvest the solar radiation into various forms is a crucial and significant task since presently available conventional energy sources are fossil, hazardous and expensive. Recently, nanostructured materials, building blocks of various devices, have received great attention due to their large aspect ratio, surface area and unique physical and chemical properties. In this direction, the proposed project is aimed to develop a new class nanostructures i.e. HSNs and investigate their performance as photocatalyst. Initially, we will develop a high quality HSNs using three-step process: seeding, first order nanostructures (nanorods as stems), and second order hierarchical structures (nanoparticles, nanohairs, nanorods). Then, we will probe the impact of growth conditions on their physical and chemical properties. Finally, the best quality HSNs will be adopted for the development of SFCs and studied their photocatalytic performance as a Nano Reactor for Hydrogen Fuel (NRforHF).