RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'ESD protection design methodology' to be submitted under Fourth Framework.

assistant: **Abstract**

To gain insight in ESD-problems and to investigate possible design options for a well-established smart power technology, as well as design and processing options for an advanced VSLI technology with the aim of a robust ESD performance;To investigate and optimize the behaviour of protection devices under different ESD stress models, including Human-Body Model and Charged Device Model,To provide basic physical models that are still lacking and that are relevant for ESD-modelling,To develop respective TCAD code and make it commercially available.A design methodology will be developed that employs device and circuit simulators to devise and to optimize integrated circuit ESD protection structures. The design methodology for production will change from the current largely-empirical approach, based on extensive destructive testing, to TCAD-guided critical parameter evaluation, validated by a relatively small number of specific high current measurements.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Targeting Innate Lymphoid Cells', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

TILC focuses on Innate Lymphoid Cells (ILCs). ILCs are a newly discovered type of lymphocyte, and their study opens up new perspectives for understanding and manipulating of immunity. ILCs include cytotoxic ILCs (NK cells) and helper-like ILCs (ILC1, ILC2 & ILC3). Studies of ILC2 cells have advanced considerably, but much remains unknown about the respective roles of NK, ILC1 and ILC3 cells. TILC aims to explore new frontiers in ILC biology, by focusing on these subsets of ILCs in mice and humans, through five specific aims.1. NK cells, ILC1 & NCR+ILC3 are known to express NKp46 in humans and mice, but the nature of the NKp46 ligands remains unclear, limiting our understanding of the biology of these three major ILC subsets. We thus aim to identify the NKp46 ligands, building on our preliminary data showing that Complement Factor P (CFP, Properdin) is involved in NKp46 recognition, hence revealing an unprecedented mode of immune recognition.2. We also aim to create new mouse models selectively targeting these ILC subsets in vivo. We will then use these models for dissecting out the selective roles of ILC subsets in two major immune functions: cancer surveillance and gut homeostasis. 3. In cancer, we will investigate the contribution of these cells to tumor editing. 4. In the intestine, we will focus on the homeostasis of the cecum and appendix. These organs were long considered to be vestiges of evolution, but our own recent findings and those of phylogenetic studies have challenged this notion. We thus aim to address the role of ILC subsets in the cecum/appendix, and determine whether these organs serve as a refuge for repopulation with commensals after dysbiosis. 5. Finally, we aim to identify patients with deficiencies in ILCs, to dissect the function of these cells
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'EXPeriment driven and user eXPerience oriented analytics for eXtremely Precise outcomes and decisions' to be submitted under Horizon Europe.

assistant: **Abstract**

Extreme data characteristics (volume, speed, heterogeneity, distribution, diverse quality, etc.) challenge the state-of-the-art data-driven analytics and decision-making approaches in many critical domains such as crisis management, predictive maintenance, mobility, public safety, and cyber-security. At the same time, data-driven insights need to be extremely timely, accurate, precise, fit-for-purpose, and trustworthy, so that they can be useful. ExtremeXP will handle the complexity of matching extreme needs with complex analytics processes (i.e., processes that involve and combine ML, data analysis, simulation and visualization components) by placing the end user at the centre of complex analytics processes and relying on user intents and running experiments (i.e., trial and error) to prune the vast solution space of possible analytics workflows and configurations i.e., “variants”. Its main goal is to create a next generation decision support system that integrates novel research results from the domains of data integration, machine learning, visual analytics, explainable AI, decentralised trust, knowledge engineering, and model-driven engineering into a common framework. The overarching idea of the framework is to optimise the properties of a complex analytics process that the end user cares about (e.g., accuracy, time-to-answer, specificity, recall, precision, resource consumption) by associating user profiles to computation variants. The framework is envisioned as modular and extensible, orchestrating different services around an Experimentation Engine: Analysis-aware Data Integration, Extreme Data & Knowledge Management, User-driven AutoML, Transparent & Interactive Decision Making, and User-driven Optimization of Complex Analytics. The framework will be validated
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Role of lysophosphatidic acid in the pathophysiology of spinal cord injury' (ROLPASCI).

assistant: **Innovation**

Traumatic spinal cord injury (SCI) causes permanent functional deficits due to damage to neurons and supporting cells. The primary mechanical injury triggers inflammatory changes that develops within hours and continues for several days after the injury, which then results in further exacerbation of tissue loss and functional impairments. Reducing the inflammatory response after SCI can therefore be expected to reduce secondary tissue damage and limit functional deficits. A number of mechanisms underlie the recruitment of leukocytes from the peripheral circulation, and the activation of these cells and endogenous microglia and astrocytes within the injured spinal cord. However, the molecules that trigger these responses are not completely known. Lysophosphatidic acid (LPA) is a potent, biologically active lipid mediator that has many physiological functions such as cellular Ca2+ homeostasis and regulation of cytoskeleton, proliferation and survival, adhesion and migration. Recent observations suggest that LPA might be also involved in inflammation. We have preliminary data suggesting that LPA causes a rapid and potent activation of the inflammatory response in the spinal cord, which leads to demyelination and functional impairment. LPA may mediate its effects by signaling via 4 G-protein coupled receptors (LPA1-4). Selectively blocking the receptors involved in detrimental pro-inflammatory responses without affecting those that either are not involved in the pathophysiology of the SCI or might be exerting tissue protection may lead to new interventions to promote repair after SCI, for which there is currently no effective therapy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Rtd of a new eco-efficient technology to manufacture enamelled copper wire without noixous emission of solvents to the atmosphere (ECOWIRETEC)' (ECOWIRETEC).

assistant: **Concept**

SECTOR: Enamelled copper winding/magnet wire. It is a technically critical product used in electricity generation, motors, self-propulsion, transformers, traction (railway), automation, etc, applications where the enamelled magnet wire has to suffer hard conditions (specially temperature).PROBLEM: In the actual process (obselete) is using a basis coating product bath (35% resin and 65% solvents).Problems are:-ENVIRONMENTAL (the process causes toxic emissions of solvents to atmosphere);- HEALTHY (laboralrisks in handling and transport the solvents), and;- TECHNOLOGICAL (high energetic and maintenance costs).Consumption of enamelled wire in Europe: 350.000 tons/year (solvents consumpted: 20.475 tons/year). Consumption of enamelled wire in Worldwide: 1.300.000 tons/year (solvents consumpted: 76.050 tons/year).OBJECTIVE: the objective is solve this problem trough a RTD project, developing a CLEAN TECHNOLOGY (ULTRA VIOLET RADIATION TECHNIQUE) and using a NEW BASIS COATING PRODUCT (WITHOUT SOLVENTS).This INNOVATING TECHNOLOGY (new in sector worldwide) will allows to comply the future European Standard: Guideline of the Council 1999/13/CE of 11/3/99 (volatile organic compounds emission due to the solvent usage in certain activities and installations) to be effective before April 30th 2001 for the European copper wire manufacture sector.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'rev.ng: a tool for security assessments of emerging and legacy platforms' (2014-2020) under Horizon 2020.

assistant: **Objectives**

Cyberattacks are one of the most challenging threats modern societies have to face.In fact, along with the growth of IT infrastructure, threats against them have been raising too.While a lot is being done, certain environments, in particular in the IoT area, are receiving little attention by cybersecurity experts.One of the key reasons for this is the almost total lack of tools to perform security assessments on them.Specifically, these areas lack reverse engineering tools, which allow analysts to analyze software for which the source code is not available.The absence of reverse engineering tools makes it extremely hard, if not impossible, to perform security assessments on such platforms.The reason for this is the dominance of the market leader (turnover 14000000+ EUR in 2017, EBITDA of 13000000+), which has little incentive to innovate in market niches which would justify the investment.In this proposal, we aim to bring to commercial maturity rev.ng, a tool developed by our company.rev.ng is the result of a multi-year research effort, with the aim of being able to handle a diverse set of platforms in a unified way.This approach is radically revolutionary in the reverse engineering field and allows us to target market niches which would not be profitable to our competitors.Our product has already been validated both by SMEs performing security assessments and large corporations performing large scale analysis of software such as Google.The goal of this proposal is getting the resources to refine some critical aspects of the feasibility study we already performed, that will lead us to devise the best path to transform our small company, currently mainly focused on consulting, into a scalable company developing a state-of-the-art reverse engineering product.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The Digital Disruption of Health Research and the Common Good. An Empirical-Philosophical Study' (2014-2020) under Horizon 2020.

assistant: **Objectives**

In the last three years, every major consumer technology company has moved into the health research domain. We are witnessing a digital disruption of health research, or a “Googlization of health research” (GHR). This project will be the first wide-ranging, interdisciplinary study of GHR. Its aim is to develop a normative framework for personal health data governance in this setting, where digital health and digital capitalism, and codes of research ethics and the lawlessness of the Internet economy, intersect. I contend that the most pressing challenge at stake in this new model of research is less the question of individual privacy than the question of collective and societal welfare, and that existing governance frameworks that seek to increase individual control over data are ill-suited to address this. Commons- and solidarity-based approaches, which seek to enhance collective agency and control, are thus promising alternatives. However, these approaches allow for only one conception of the common good, while a plurality of competing conceptions are at work in GHR, including “increased efficiency”, “greater inclusivity”, and “economic growth”. This plurality must be taken seriously to avoid theory-practice discrepancies and to develop viable governance solutions.The project will develop a normative framework that can both foreground collective benefit all the while accounting for this ethical plurality. To do this, my team will first map the different conceptions of the common good – or “moral repertoires” – that motivate actors in several GHR-type collaborations. Using an empirical-philosophical methodology, we will critically evaluate these repertoires and the value trade-offs they involve in practice. Next, we will explore the viability of commons- and solidarity
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Advancing the Science for Aviation and ClimAte' under Horizon 2020.

assistant: **Concept**

Non-CO2 emissions of aviation may impact climate as much as aviation's carbon dioxide (CO2) emissions do. However, the impact the non-CO2 effects (e.g., ozone and methane from NOx emis-sions, contrails, indirect aerosol effects) is associated with much larger uncertainties, some of these effects might result in a relatively large cooling.ACACIA has four aims for scientifically based and internationally harmonised policies and regulations for a more climate-friendly aviation system. (1) We will improve scientific understanding of those impacts that have the largest uncertainty, in particular, the indirect effect of aviation soot and aerosol on clouds. (2) We will identify needs for international measurement campaigns to constrain our numerical models and theories with data and we will formulate several design options for such campaigns. (3) Putting all aviation effects on a common scale will allow providing an updated climate impact assessment. Uncertainties will be treated in a transparent way, such that trade-offs between different mitigation strategies can be evaluated explicitly. This helps our final aim (4) to provide the knowledge basis and strategic guidance for future implementation of mitigation options, giving robust recommendations for no-regret strategies for achieving reduced climate impact of aviation.To this end, ACACIA brings together research across scales (from plume to global scale), from the laboratory experiments to global models, and it proceeds from fundamental physics and chemistry to the provision of recommendations for policy, regulatory bodies, and other stakeholders in the aviation business. Additionally, ACACIA will cooperate with international partners, both research institutions and organisations.


**Keywords:** green flight, non-CO2 effec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Earth-Abundant Metals with Exclusively Achiral Ligands for Sustainable Chiral-at-Metal Catalysis' (EARTHCAM).

assistant: **Innovation**

Asymmetric catalysis relies on the design of chiral catalysts and is dedicated to the economical generation of non-racemic chiral compounds, which are building blocks for the production of drugs, agricultural chemicals, flavors, fragrances, and materials. Chiral transition metal complexes constitute an important class of chiral catalysts and are typically synthesized by combining metal salts or organometallic precursors with chiral ligands. A neglected approach follows a different direction and exploits the generation of metal-centered chirality in the course of the assembly of achiral ligands around a central metal. Our group has pioneered the general use of such chiral-at-metal catalysts from noble metals, with the metal center both serving as the exclusive stereogenic center and at the same time acting as the reactive center for catalysis. The design of reactive chiral-at-metal catalysts based on earth-abundant metals, which have economical and environmental benefits, is the focus of this proposal. The design strategy appeals for its combination of sustainability (earth-abundant metals) and simplicity (achiral ligands). Furthermore, without the requirement for chiral motifs in the ligand sphere, untapped opportunities emerge for the design of chiral 3d metal complexes with distinct electronic properties and unique architectures. This unexplored chemical space for chiral catalysts will be applied to the challenging enantioselective functionalization of C(sp3)-H bonds with inexpensive and sustainable 3d metal catalysts.The implementation of chiral-at-metal catalysts from earth-abundant metals will rely on taming the high lability of coordinative bonds of 3d metals to warrant a satisfactory configuration stability. This will be addressed by exploiting the chelate effect
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Solid Matrices for Bioprocessing', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Objectives and content Manufacturers of food products, biopharmaceuticals and immobilized enzymes have a clear need for improved solid, particulate matrices which can be used for purification and immobilization of proteins (enzymes, antigens and antibodies). Today there are no materials which fulfil all the customers' demands on productivity, inertness, stability, flow properties and price. By removing this bottleneck it would be possible to develop large-scale industrial applications for solid matrices and to open up new market niches. Immobilized enzymes are potentially very useful as biocatalysts in food processing. Similarly, immobilized antigens and antibodies have potential for the very large scale purification of biopharmaceuticals. The objective of this project is to develop and evaluate new solid matrices which meet industry's needs. New polymerisation, surface modification and immobilization technology will be applied in the development of new matrix prototypes and a prototype process for large scale bead production. By improving the capacity, flow properties and kinetics of the matrices and by reducing the production cost it is expected that the performance/price ratio will increase by 5-10 times. Chemical leakage is expected below 10 ppb which is required for food applications. Enzymes will be purified by chromatography using the new matrices. The enzymes will be bound to activated matrices, and the immobilized enzymes with improved performance will be characterised. The immobilized enzymes will subsequently be used for development of new processes in the area of food processing. Immobilized antigens and antibodies will be applied to the development of new processes for purification of biopharmaceuticals. Processes which involve biocatalysts are favourable c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'A compact roentgen micro-analyser'.

assistant: **Innovation**

In the last decade, many instrumental analytical tiquues which previously only provided average information on a large sample have developed microscopic equivalents. The drive for this development is twofold: (1) the increasing degree of material complexity and (2) the arowing need to measure local properties of natural and man-made materials. Unfortunately, the most well-established microscopic method of elemental analysis (EPXMA - electron probe X-ray micro-analysis) only yields major element information In many disciplines, however, such as forensic science and materials characterisation in the cultural heritage sector, there is an acute and growing need for compact and non-expensive equipment which permit to obtain minor and trace-level compositional fingerprints of various materials and sample shapes for specific areas of large objects and/or from minute samples. The overall objective of the present proposal is to develop and introduce on the market a compact, light-weight and inexpensive micro-beam XRF instrument that allows local analysis of sub-mm samples with minor/trace level sensitivity and that can be used either as a table-top unit in a laboratory environment ('ex situ' measurements, (e.g. of forensic materials gathered at a crime site) but is also readily transportable and positionalble so that is can be employed for 'in situ' measurements (e.g., of artistic objects on display in a museum), providing routine compositional information with a lateral resolution of 50-200 um at the 10 -100 pa absolute/10-100 ppm relative level of detection. The COPRA device will only need external AC power for its operation. Two prototype devices will be designed and constructed, consisting of: * a freely positionable measuring head, containing the following components: (i)a