RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Metal Organic Frameworks for carbon dioxide Adsorption processes in power production and energy Intensive industRies' in the context of a Horizon 2020 call.

assistant: **Objectives**

Power supply and carbon-intensive industries account for a large share of CO2 emissions. Shifting towards a low-carbon economy requires cost-effective carbon capture solutions to be developed, tested and deployed. Current solutions do not offer sufficient performances. Adsorption processes are promising alternatives for capturing CO2 from power plants and other energy intensive industries as cement, steel, or petrochemical industries. In this regard, Metal Organic Frameworks (MOFs) are a widely studied class of porous adsorbents that offer tremendous potential, owing to their large CO2 adsorption capacity and high CO2 affinity. However, the performances of MOF-based carbon capture technologies have not been fully evaluated. MOF4AIR gathers 14 partners from 8 countries to develop and demonstrate the performances of MOF-based CO2 capture technologies in power plants and energy intensive industries. After identifying the best MOFs in WP1 and validating them through tests (e.g. stability and selectivity) in WP2, the most promising will be produced at larger scale and shaped in WP3. WP4 will conduct simulations to study MOFs behaviours in two adsorption processes: VPSA and MBTSA and optimise them. Both solutions will be tested at lab scale in WP5. In WP6, 3 demonstration sites across Europe will prove the cost-efficiency and reliability of MOF-based carbon capture in CO2 intensive sectors: power supply, refineries and waste incineration. To ensure a wide development of the solutions developed, WP7 will focus on techno-economic analysis, LCA and WP8 on social acceptance and replicability. MOF4AIR aims to foster the uptake of CCS technologies by providing a TRL6-reliable solution matching end users' needs, notably by cutting CCS energy penalty by more than 10%. The solutions d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'A LAB-ON-A-CHIP DEVICE FOR PURE CIRCULATING TUMOR CELL ISOLATION FROM WHOLE BLOOD FOR CANCER THERAPY' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The overall objective of pureCTC is to realize a comprehensive lab-on-a-chip platform that redefines the state-of-the-art technology to address all the requirements for fast, efficient and reliable CTC isolation/purification from whole blood.CTCs are rare cells that originate from tumors, and which travel in the human circulatory system to eventually spread the disease to other organs. Consequently, analysis of CTCs is crucial for revealing the mechanisms of cancer and developing new treatments. However, only 1-10 CTCs are present per mL of blood against billions of peripheral blood cells. The extreme rarity and inherent heterogeneity of CTCs implies a single-cell analysis strategy. Therefore, a highly selective, efficient and reliable system yet providing high throughput is mandatory. Cell labeling based strategies are inefficient for CTC analysis, since CTCs express biomarkers with high heterogeneity. Label-free methods based on size lack the ability to distinguish CTCs from leukocytes, and methods based on electrical properties fail to provide sufficient enrichment or throughput levels.To address these challenges, pureCTC proposes the development a microfluidic platform for successive enrichment, identification, and isolation of CTCs at the single-cell level, where a blood sample taken from a patient is directly injected and utilized without any pre-treatment. Namely, the platform is composed of 3 modules that work in tandem, each of them having innovative aspects: enrichment via 2D hydrodynamic-dielectrophoretic separation, identification via synchronous electro-optical detection, and isolation via a dielectrophoretic valve.The proposed research will undoubtedly contribute to the knowledge-based economy and European society, specifically on cancer research by provid
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Cellular and molecular mechanisms of neuronal retrograde signaling (RETROGRADE SIGNALING)' to be submitted under Fifth Framework.

assistant: **Abstract**

In addition to the classical, polarised release of neurotransmitter that takes place at synapses, neurones communicate with each other through another, and less well understood mechanism called retrograde inhibition. Here neurones emit a messenger molecule from their somatodendritic membrane when they fire action potentials, and this molecule induces an inhibitory signal in the axon and synaptic terminals ofpresynaptic neurones. The aim of this proposal is to test whether retrograde inhibition results from the exocytotic release of classical neurotransmitters from the somatodendritic domain of the releasing neuron, and to compare this type ofexocytosis with that taking place at axon terminals. The participation of novelexocytotic proteins, which are insensitive to clostridia neurotoxins, will be investigated. Methods will include molecular biology, immunohistochemistry, electron microscopy, patch-clamp recording and amperommetry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'NETWORKED ELECTRONIC STORAGE AND COMMUNICATION OF TELEMATICS APPLICATIONS PROGRAMME RESULTS' (NECTAR), addressing dissemination and exploitation.

assistant: **Impact**

NECTAR will set up and run an electronic repository containing public results of telematics engineering projects and on the application of the techniques involved. The electronic data will be stored, processed and updated for intercommunication with the telematics and other related areas of the Fourth Framework Programme, as well as EUREKA. Overall, it will provide the basis for a model illustrating disciplinary aspects of telematics engineering and how multi-sectoral applications can make the most of telematics infrastructures. Data will also be refined to adapt access level and feedback to a wide range of users.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Innovative Communities On Neutral Islands for Climate'.

assistant: **Concept**

ICONIC is a forward-looking project designed to enhance energy independence, climate neutrality, and sustainable development in rural and island communities across Europe. Addressing the distinct socio-economic and environmental challenges of these areas, ICONIC deploys advanced technologies such as renewable energy systems, smart water management (solar-powered desalination, intelligent irrigation), off-grid biogas systems, and sustainable mobility solutions. These innovations are tested through real-world pilot demonstrations in Inis Mór (Ireland), La Graciosa (Spain), and Berchidda (Italy), where the project works closely with local stakeholders to co-design tailored solutions.ICONIC also fosters social innovation, emphasizing community engagement and multi-actor collaboration to ensure long-term sustainability. By promoting energy communities, circular economy practices, and peer-to-peer energy trading, the project strengthens local governance and empowers citizens to lead the transition to climate-neutrality. Digital platforms, including predictive analytics and digital twins, support integrated management of resources like energy, water, and mobility, enabling data-driven decision-making for both local authorities and residents.ICONIC's interdisciplinary approach contributes to various EU strategies, advancing the green and digital transitions in rural areas. By promoting social innovation, offering replicable models, and establishing a robust replication strategy, ICONIC ensures its impact extends beyond the pilot regions, providing a blueprint for rural and isolated communities across Europe and beyond. Through training programs, policy recommendations, and capacity-building workshops, ICONIC not only drives technological innovation but also fosters economic res
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'EUROPE EGYPT NETWORK FOR PARTICLE PHYSICS' (EENP2).

assistant: **Innovation**

We propose an exchange programme to promote the scientific collaboration in particle physics and related technologies between a network of Egyptian Universities and EU member states Academic Institutions which have already originated innovative transfer of knowledge towards Egypt. The main objectives of the joint exchange programme are:• the reinforcement of the Europe-Egypt scientific collaboration. In particular in past years both France and Italy have funded initiatives in the field of particle physics and related technologies to boost Egyptian interest and personnel training. The present proposition intends to further improve the collaboration by especially allowing long term visits of young and senior Egyptian scientists to perform advanced research on fundamental particle physics in the framework of worldwide large collaborations. Moreover the programme would offer  the possibility to second EU researchers to Egypt to originate advanced research activities, advice on the development of the local infrastructures and monitor the success of the transfer of knowledge;• the establishment of a important scientific collaboration between Italy and France on advanced physics concepts and technologies. Although some researchers of the EU Academic Institutions involved in the proposal have already collaborated through  the CERN experimental physics program, the possibility of building up an independent common research program would boost enormously the joint research capability. It should be mentioned that the researches involved in these EU institutions can offer an impressive expertise to the  activities relevant for this proposal. Their collaboration could therefore have an important European long term impact on the progress  of the physics concept and technologies hereby
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'EUROPEAN NETWORK FOR MANAGEMENT OF ARTHROPOD RESISTANCE TO INSECTICIDES AND ACARICIDES' (ENMARIA), addressing dissemination and exploitation.

assistant: **Impact**

The development of resistance to insecticides and acaricides by the arthropod pests poses a serious and increasing threat to the sustainability of pest management practices throughout the world. In Europe, resistance is now rapidly diminishing the supply of pesticides considered vital for controlling many crop and livestock pests.By promoting more frequent application of chemicals, often at higher rates or in mixtures, it also has adverse implications for the environment, food industry and human safety.The Concerted Action outlined in the proposal will provide, for the firsttime in Europe, a forum for the open exchange and dissemination of data on the incidence of resistance, the transfer of techniques for diagnosing resistance at the toxicological, biochemical and molecular levels, and the promotion of control strategies that prevent or delay resistance development. This will be achieved by convening two resistance management workshops, promoting collaborative research projects, and by compiling a comprehensive resistance database that will be freely accessible to all European researchers and other interested parties. The CA will also provide limited support for short-time training visits aimed at strengthening research in regions that lag behind in the development of programmes for resistance management. Workers in 16 organisations in 13 EU and EFTA countries have enthusiastically committed themselves to this exciting new initiative, and to achieve a level of international collaboration in resistance research that is currently unprecedented anywhere in the world.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Photochromic Systems for Solid State Molecular Electronic Devices and Light-Activated Cancer Drugs' in the context of a Seventh Framework call.

assistant: **Objectives**

Photochromic molecules, or photochromes, can be reversibly isomerized between two thermally stable forms by exposure to light of different wavelengths. Upon isomerization, properties such as excitation energies, redox properties, charge distribution, and structure experience significant changes. These changes can be harnessed to switch “on” or “off” the action of a variety of photophysical processes in the photochromic constructs, e.g., energy and electron transfer. Until now, the focus of my research has been to show proof of principle for a large selection of molecule-based photonically controlled logic devices (solution based) with the functional basis in the switching of the transfer processes mentioned above. Now, I wish to extend the study to include experiments in the solid state, e.g., polymer matrices. Taking the step into doing solid state chemistry is not only a prerequisite for any real-world application. It will also allow for experiments that cannot be performed in fluid solution, such as aligning molecules in a stretched film for chemistry with polarized light, and immobilization of molecules for selective addressing in a three-dimensional array of volume elements. Furthermore, I intend to investigate the possibility to photonically control the membrane penetrating and the DNA-binding abilities of photochromes, aiming at, in a long-term perspective, light-activated cancer drugs. Due to the fact that both the structure and the charge distribution of a photochrome may change drastically upon isomerization, one of the two isomeric forms is often suitable for penetrating a membrane. Inside the membrane, e.g., in a cell, the photochrome can be photo-isomerized to a structure with high affinity for strong binding to DNA. Upon binding, transcription is inhibited
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'FOOD and Local, Agricultural, and Nutritional Diversity'.

assistant: **Innovation**

FOODLAND aims at enhancing the diversity of food production and consumption in six African countries displaying different stages of the nutrition transition. To this end, FOODLAND will create a network of 14 local Food Hubs that will aggregate relevant actors and serve as injection points for the introduction of innovations.FOODLAND has identified specific objectives addressing the organizational, technological, and nutritional needs of the local African food systems to be reached during the four-year project duration: 1. to detect behaviour and preferences of consumers and producers, in order to customize innovations to local sensitiveness; 2. to develop and implement organizational innovations, aimed at boosting coordination among food operators; 3. to develop, test, and validate (open) technological innovations in laboratory and in the field; 4. to disseminate knowledge of solutions towards malnutrition reduction and innovations. Through participative approaches in the Food Hubs, FOODLAND will create and validate (TRL 5) 12 prototypes for crop and fish farming and food processing systems that will deliver 17 novel food products. FOODLAND will empower smallholder farmers and food operators, will foster nutrition-responsive and sustainable agro-biodiversity, will reinforce the productivity and resilience of food supply chains, and will create new market opportunities at both the local and global scales, thereby encouraging the flourishing of rural communities. These achievements will benefit both African and European consumers by providing them with traditional-based, healthy, nutritious foods, while encouraging the diffusion of African diets and aiding the fight against malnutrition, particularly in women and children.


**Keywords:** Food, supply chain, food systems,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'aCtive sEcurity foR connecTed devIces liFecYcles' (CERTIFY).

assistant: **Innovation**

Cyber-attacks get more sophisticated every day, thus affecting a large number of IoT-related infrastructures and raising security and privacy concerns of consumers and businesses. Security management of IoT infrastructures encompassing full lifecycle of products and continuous certification are fundamental tools to guarantee a high-level of security, as emphasized by the European Union Agency for Cybersecurity (ENISA) Cybersecurity Act (CSA).CERTIFY defines a methodological, technological, and organizational approach towards IoT security lifecycle management based on (i) security by design support, (ii) continuous security assessment and monitoring (iii) timely detection, mitigation, and reconfiguration, (iv) secure IoT Over-The-Air (OTA) updating, and (v) continuous security information sharing.To ensure the security compliance throughout the lifetime of the device, we propose the design and implementation of a cybersecurity lifecycle management framework for IoT devices. The framework is intended to support the device security management by collecting and sharing relevant security information both internally (via monitoring and self-assessment services) and externally, e.g., by interacting with device manufacturers, threat databases, certification authorities, Information Sharing and Analysis Centres (ISACs), and more. The received information is meant to support the local decision making with respect to the security, monitoring, updating and configuration of the device. Moreover, this information sharing will enable a continuous risk assessment, gathering evidence that could agile future certifications.CERTIFY's provides IoT stakeholders with mechanisms achieving high-level of security. CERTIFY will detect and respond to a wide spectrum of attack, in a collaborative/
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Studies towards the total synthesis of taxoids' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Research objectives and content The overall objective of this proposal is to develop efficient synthetic routes that improve the practicality of the construction of taxoid analogues. Development of methods for the synthesis of such molecules formingthe basic structures of biologically active products, is an area of active investigation. The proposed pathway starts from methylcyclopentenone and benzoic acid methylester, which are readily available bulk chemicals, and places emphasis on step efficiency, simplicity and environmental factors. Furthermore, it allows numerous structural changes to be made in a very limited number of steps. The appropriateness of the experimental approach and procedures of the proposed scheme appears sufficiently promising to warrant completion. I Training content (objective, benefit and expected impact) I will learn a great deal from this experience in terms of modern instrumental methods and laboratory techniques. Undoubtedly such an undertaking will allow me to reach a high level of knowledge and secure for me a job back in my country. Links with industry / industrial relevance (22) The Rhtne-Pounlec Rorer company is interested to screen synthetic intermediates for biological activities.