RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Early Earth, Mars and Venus as Exoplanets (EASE)' (EASE) under Horizon Europe.

assistant: **Objectives**

The era of the James Webb Space Telescope (JWST) has opened a new chapter in exoplanetary research. We cannot understand exoplanets without looking back at the cradle of life as we know it - the Earth. Why did the Earth become a habitable planet? Why did Mars and Venus evolve differently? What would JWST see if it looked at the solar system planets as they were billions of years ago? My team will investigate the long-term evolution of the atmospheres and spectral fingerprints of Earth, Venus, and Mars.I propose a unique joint evolutionary study of volcanism, atmospheric escape to space, and spectroscopy. My team will use numerical models at the cutting edge of modern development and connect their outputs to the growing list of JWST spectra of exoplanets. The team will model interior processes, the evolution of lower and upper atmospheres, and the evolving atmospheric spectra of Earth, Venus, and Mars and their possible exoplanetary analogues. Our predictions of spectral features of these three planets at different evolutionary stages will be critical for the astrophysics community to identify potential habitable worlds outside the solar system, and forecast their future evolution. My deep expertise in stellar and planetary evolution makes me uniquely well-placed to lead this project.This project will not only significantly expand our current knowledge of the evolution of the Earth, Venus, and Mars, but will also place much better constrains on the probability for a terrestrial planet to evolve into a habitable world. The team will in particular characterize possible “failed” analogues of Earth and investigate if they could have become habitable planets under slightly different conditions. By studying for the first time this unique combination of factors that are crucial
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Finance and Risk in the Lives of Working People in Market Socialist Asia' (FinancialLives) under Horizon Europe.

assistant: **Objectives**

The rise of household financial activities such as mortgages, consumer credits and private insur-ance among working people in China, Vietnam and Laos signals new patterns of accumulation alongside the commodification of labour that has been central to their national development. In these market socialist countries, where marketization is deepening under the rule Communist par-ty states, governments are turning to financialization to ensure growth and fill the gaps of social provisioning. Via financial products and services, debt and private risk management are being promoted to working people as the means to wealth accumulation and social protection, drawing household reproduction into the financial system. Meanwhile, working households actively deploy risk management tools marketed by financial institutions for their own purposes, thereby playing a constitutive role in how financialization unfolds. Hypothetically, the ensuing normalisation of risk exposes working households to increasing systemic risk that characterises global finance, with far-reaching implications for the reproduction of working lives and the sustenance of the market socialist economy. Enquiring into household and institutional processes that bind labour and finance through the production, governance and management of risk, FinancialLives uses the concept politics of risk to comparatively unpack these implications across the three countries. As an anthropological project, it includes five ethnographic studies examining the household pro-cesses and negotiations referred to as financial householding as well as the practices of risk commodification by commercial banks in their interactions with working people. The project is timely and ground-breaking in illuminating the differing ways in which risk has
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Cross-linguistic influence during real-time processing in child heritage speakers'.

assistant: **Objectives**

The project CLEAR (Cross-Linguistic influence during real-time procEssing in child heritAge speakeRs) investigates the role of crosslinguistic influence in real-time sentence processing to fill the gap in the ongoing debate about whether languages interact in the mind of a bilingual child. Some argue that the general bilingualism effect, rather than the cross-linguistic influence, affects language comprehension. What is lacking in this field of research, however, is a systematic understanding of what happens in real-time processing. We focus on cross-linguistic influence in pronoun interpretation by testing severely understudied bilingual population, i.e. child heritage speakers of Croatian. We approach the phenomenon in a new and unique way by examining the crosslinguistic influence in relation to the implicit causality bias, which is assumed to facilitate language comprehension. CLEAR takes a novel methodological approach by comparing children in three European countries – Croatia, Italy and Norway. The two language combinations, Croatian-Italian (null-subject languages) and Croatian-Norwegian (non-null-subject language) allow us to gain insight into the role of structural overlap between languages. To better understand the phenomenon, both children’s eye movements and offline responses will be measured. CLEAR will make a significant contribution to research on heritage language bilingualism by revealing whether the languages a child acquires influence each other or whether difficulties in language comprehension are due to the general bilingualism effect, i.e. limited processing abilities. The project addresses aspects that are of great importance for teachers of second/foreign languages as well as for speech and language pathologists by promoting bilingualism and int
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Optimise Citizen Mobility and Freight Management in Urban Environments' (OPTICITIES) targeting Seventh Framework.

assistant: **Abstract**

OPTICITIES’ vision is to help European cities tackle complex mobility challenges. OPTICITIES’ strategy focuses on the optimisation of transport networks through the development of public/private partnerships and the experimentation of innovative ITS services.OPTICITIES addresses both passenger and freight transport issues supporting a user-centred approach.OPTICITIES delivers significant innovation breakthroughs:- New governance scheme between public and private stakeholders through a contractual architecture fostering data quality and implementing data access policy;- European standard for urban multimodal data set including interfaces with information services;- Decision support tools based on predictive data for proactive transport management and Multimodal Traffic Control Systems connecting road traffic and public transport data in cities;- Multimodal real-time urban navigator interfaced with in-car navigation systems as a first world trial;- Urban freight navigator to support drivers and fleet operators in optimising their deliveries.The European dimension of the project is ensured by a consortium of 25 partners from 8 EU member states. The consortium includes 6 city authorities, major ITS actors (research institutes, information service providers, car industry) and the most important networks of European cities and international public transport operators.Led by public authorities the consortium supports 3 key approaches: effectiveness of solutions ensuring deployment perspectives of maximum 5 years; scalability of services tailored to diverse European urban typologies; transferability of results to foster further deployments in other European cities.OPTICITIES’ main expected impacts are:- 6% modal shift inducing a yearly gain of 1.5 MT of CO2- Increase in market
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Defining the antithrombin measurand: role of proteoforms in harmonisation of diagnostic tests in thrombosis' (HarmonizATforms) targeting Horizon 2020.

assistant: **Abstract**

Current medical tests for antithrombin deficiency generally measure the overall activity, being blind for the actual proteoforms of AT that contribute to the test. To ensure accurate test results, a traceability chain needs to be in place, which requires the accurate definition of the exact analyte to be measured. I hypothesize that an in-depth understanding of the pathological molecular proteoforms of antithrombin (AT) will allow for the identification of clinically relevant proteoforms and enable test harmonization, resulting in a test with a well-defined clinical outcome that are actionable by clinicians. Mass spectrometry (MS) is an emerging technique in the field of clinical chemistry, which is well suited for the detection of proteoform characteristics and outperforms testing methods based on immunoassays. Therefore my aims are 1. To develop a mass spectrometry based test for the quantification of individual characteristics of molecular proteoforms of AT. 2. Analytically validate the developed method according to clinical chemistry procedures, and 3. Assess the role of MS based test for the standardization of AT tests.  I am a passionate scientist with a strong background in the development of MS-based tests for proteins. I plan to perform the project in collaboration with my supervisor, who has large experience in medical test development and the ECAT foundation, who is specialized in proficiency testing of AT and test harmonization.  This project will allow me to obtain skills and experience to oversee and develop a clinical test from biomarker discover to test evaluation and implementation, specifically in the niche of thrombosis and haemostasis, as well as the transferable skills required to eventually establish my own independent research group.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Scale Business and Technology to Impact on Disease Research by with Lossless and Efficient Data Analysis' under Horizon Europe.

assistant: **Concept**

Aren’t we expecting from disease research that all available data is being used? Yes! Yet one of the biggest hurdles is the data variety when to studying underlying mechanisms or prioritizing targets for novel treatments. Ultimately stalling projects and resulting in low output and quality. knowing01 GmbH is a deep tech software company founded in 2020 in Munich, Germany that gives Life Scientists full control of all their research data. Dr. Nikola Müller (founder and CEO) has spearheaded the project since 2014, when the idea budded during her academic research at Helmholtz Munich.  The knowing01 solution is a software-as-a-service (SaaS) suite that allows the user to connect and explore omics data no matter their biodata type. Our innovative knowledge-graph based translation approach empowers scientists to run analyses across data types and compare different sets in their biological context. We additionally offer on client premise, licensed software. Our next challenging milestone is to scale a) by innovating the business and b) by having a critical assessment of the technology. We aim to exploit our niche market position. We are specifically aiming to be attractive to key partners that offer our together with their own services. We need scale our infrastructure and database-related technologies alongside with the business. Only both will allow us to future-proof our business paving the way for a sustainable business.   Dr. Nikola Müller will profit from being part of the Women Leadership Program by sharpening negotiation skills, learning how to improve public visibility and finally, getting into potent female-friendly investor networks. Compared to classical IT, biotech or digital health companies, our offering opens a yet unexplored niche, which is why we will enormo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Improved reservoir water destratification (AQUAERATION)'.

assistant: **Concept**

Scientific objectives and approach:The research & development project which will be carried out over a two year period, will involve manufacturing several model & prototype Aquaerator units & running a series of laboratory tests & an extended programme of trials in Thames water's Wraysbury reservoir. These tests & trials will define the most effective Aquaerator design & provide the necessary database with which to compile the integral computer model. The research will also characterise the various technical factors associated with the operation of reservoirs in a variety of climatic conditions with particular emphasis on those factors, which govern the growth of blue-green algae which is an area of great concern throughout the EU in view of the inherent & intolerable pollution hazard that such organisms represent. The final task of analysing & modelling all of the gathered research data will be critically important in view of the objective to market the Aquaerator & its associated software to end users involved in processing fresh, waste & even salt water internationally.Description of the research tasks:1.1 Characterisation of existing destratification & aeration devices1.2 Characterisation of the technical factors associated with algal growth2.1 Design & manufacture of several scale model Aquaerators2.2 Design & manufacture of the dedicated Aquaerator control system2.3 Design & manufacture of several prototype Aquaerators3.1 Development of the mathematical model to be used in the main trials3.2 Preparation for the series of main reservoir trials3.3 An extended series of trials using Aquaerators in Wraysbury reservoir4.1 Detailed analysis of the results of the operational trials4.2 Detailed production specification for the commercial Aquaerator4.3 Project reporting &
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Understanding how mitochondria compete with Toxoplasma for nutrients to defend the host cell' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Once a pathogen has eluded immune defences to establish a replicative niche in the cytosol, it requires nutrients to grow—the same nutrients that host organelles need for their biogenesis and to perform cellular metabolic processes. The microbe must therefore compete with organelles for these nutrients.. This organelle-microbe competition for metabolites is a fundamental, but little understood aspect of the host–pathogen interaction. I recently defined one example of this competition, between mitochondria and the human parasite Toxoplasma gondii. During infection, Toxoplasma exploits host lipophagy to gain access to cellular fatty acids essential for its growth. To counter this, host mitochondria fuse to enhance fatty acid uptake, limiting Toxoplasma access to a key host resource and thus restricting its growth. This work shows that mitochondria—essentially domesticated parasites—metabolically defend the cell during infection, and opens several key questions that I will address in this proposal, including: a) by what mechanism do mitochondria enhance fatty acid oxidation to defend the cell against fatty acid siphoning by microbes?; b) can mitochondrial fatty acid oxidation be exploited to restrict microbial growth in vivo?; and c) do mitochondria play a broader role in cellular defence by sequestering other essential metabolites from microbes? The answers to these questions will lead to a deeper understanding of the role of mitochondria in the cellular response to microbes, and begin to address our long-term goal of understanding how human metabolism influences the progression of infectious disease. The innovative approaches I describe here are broadly applicable to dissecting the metabolic interactions between other organelles and diverse infectious agents.


**Keyword
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Advanced D.I. Gasoline Engine' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

BE95-1284 Advanced D.I. Gasoline Engine Together with tighter emission standards (phase E) that are expected in Europe after the year 2000, new limits on carbon dioxide (C02) for passenger cars are proposed by the European Parliament, thus forcing manufacturers to operate for the first time directly on the engine concept instead of working once again just on the aftertreatment of the exhaust of the conventional indirect injection gasoline engine with fuel injected ahead of the intake ports. Until now the various approaches to the DI gasoline engine, that has the potential to meet both future CO2 and pollutant emission targets, have shown the typical aspects of basic research dealing with solutions not able to be transferred into production concepts. Thus the main objective of the project is the realisation of a production-oriented ultrahigh efficient DI gasoline engine that, tested at vehicle level according to the European ECE+EUDC driving cycle, will be able to show: - more than 15% C02 reduction with respect to the today's IDI gasoline engines, i.e. 3% lower than the C02 limit at vehicle level as proposed by the European Parliament (by taking into account that 15% of efficiency increase is expected from the vehicle-side improvements); - pollutant reduction down to 0.2/0.1/0.1 g/km of CO/HC/NOx. The information resulting from the project, being highly prenormative, will assist the European Commission in delivering the phase m standards, concerning the emission level that can be achieved with an advanced DI gasoline engine. The DI gasoline engine to be developed in this project will consist of a fully integrated engine system characterized by: - optimized injection / combustion, - advanced aftertreatment with dynamic emission control, - advanced valve control At the en
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Novel molecular beacon technologies for the study of hiv-1 and other infectious agents' (BEACON).

assistant: **Concept**

The proposed research concerns molecular beacon technology in infectious diseases in general and HIV disease in particular. This is a well-timed area with numerous possible applications and where fundamental technologies in biomedical sciences are limiting and novel technologies are increasingly in demand.The first overall goal of this initial research project is to investigate the role of HIV-1 cellular viral load and antiretroviral drug-resistant variants on the antiretroviral treatment of HIV-1-infected individuals by using novel quantitative HIV-1 diagnostic assays. The assays have been previously constructed and evaluated in our laboratory and are based on molecular beacon and allele discriminating real-time PCR technologies that is the primary technology of our laboratory.Our first aim involves investigating the implications of the concentration of HIV-1 DNA in peripheral blood mononuclear cell PBMC) samples ('HIV-1 cellular Viral Load') in predicting the virological response to antiretroviral therapy. In the second aim, we will quantify minor populations of HIV-1 drug resistant strains on mother-to-infant HIV-1 cohorts.The results of the proposed studies will have a direct impact on the clinical care of HIV-1-infected individuals including Cypriot patients. The second goal is to investigate the phylogenic (subtype) distribution and spread of antiretroviral drug-resistance of HIV-1 strains from recent and long-standing patients in Cyprus.It is hoped that the grant support of the Marie Curie International Reintegration Grant will allow the principal investigator to establish a new research laboratory in the University of Cyprus in the best possible conditions and initiate my research activities.