RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Cell cycle regulation of ES cell identity and reprogramming potential' (REPLENICHE) under Seventh Framework.

assistant: **Objectives**

Pluripotent embryonic stem (ES) and germ (EG) cells differ from other stem cells in several respects. They display a characteristically ‘compressed’ cell cycle in which G1 is shortened, contain a high proportion of cells in DNA synthesis (S)-phase and lack several cell cycle checkpoints. This unusual cell cycle signature is important for maintaining their identity since cell cycle arrest, or lengthening, results in irreversible differentiation, and somatic cells assume this unusual signature when successfully reprogrammed.We have shown that ES and EG cells rapidly convert somatic cells towards pluripotency in transient heterokaryons, and this can be enhanced by genetic modification or using ES cells enriched at G2-phase. On the other hand, mouse epiblast stem (EpiS) and ES cells that lack specific repressor activities (such as Polycomb) although pluripotent, do notdominantly convert somatic cells and show increased doubling times. To determine the importance of cell cycle control for pluripotent self-renewal, we have optimised elutriation to allow the isolation of ES, EG and EpiS cells at progressive stages of the cell cycle. Pilot studies show changes in the levels of modified histones as ES cells transit the cell cycle, and increased levels of specific reprogramming factors during G2-phase. We will extend these analyses genome wide (using ChIP and RNA Seq, and high throughput proteomics) and use fluorescent microscopy to document changes in chromatin dynamics during ES cell cycle, and during somatic cell reprogramming. This will be achieved using novel micro-fluidic approaches to generate heterokaryons between ES, EG, EpiS and lymphocytes. The importance of cell cycle stage and its relevance during early events in successful reprogramming will be tested in heterokaryo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Flexible Multifunctional Bendable Integrated Light-Weight Ultra-Thin Systems' (FLEXIBILITY), addressing dissemination and exploitation.

assistant: **Impact**

FLEXIBILTIY aims at significantly advancing the competitiveness of Europe in the area of multifunctional, ultra-lightweight, ultra-thin and bendable OLAE systems. The developed OLAE components include disposable and rechargeable batteries, solar cells, DC charging electronics, loudspeakers, audio amplifiers, analogue signal generators, motion and temperature sensors, RF receiver circuits, as well as a touch screen. By combination of these components, a variety of novel multifunctional OLAE systems is enabled. Based on a fully printed sound module, the following complex demonstrators are developed:\tTextile integrated audio module including broadcast radio and solar supply\tActive receiver tag for wireless streaming of acoustic data and advertising\tSecurity tag system with acoustic alarm, motion and/or temperature sensorsFor the realisation of these systems, the advantages of several flexible OLAE technologies are combined, while keeping cost issues in mind: e.g. a) R2R printing offering ultra-low costs per area for components requiring large areas (e.g. loudspeaker, high-power audio amplifiers and solar cells), 3-D integration, as well as the integration of heterogeneous devices on one single substrate; and b) compact (down to 10 micrometer gate length), super-fast (> 200 MHz transit frequency, mobilities > 10 cm2/Vs), low-loss IGZO thin-film technology to enable wireless communication systems. To make efficient circuit development in standard CAD tools possible, design-kits including scalable models and automated layout templates are developed. Interface and packaging issues are studied for full system integration on a common flexible foil enabling bending radii down to 1 cm. FLEXIBILITY combines the complementary competences of 3 large companies, 4 SMEs, 1 researc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Innovative Synthesis in Continuous-Flow Processes for Sustainable Chemical Production' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The SYNFLOW vision is the paradigm shift from batch-wise large volume processes in pharmaceuticals, fine chemicals and intermediates production comprising many separate unit operations towards highly integrated but yet flexible catalytic continuous flow processing. For this purpose, SYNFLOW develops a unique integrative approach combining molecular understanding of synthesis and catalysis with engineering science in process design and plant concepts, aiming at an efficiency breakthrough in process development and operation. The SYNFLOW mission is to overcome the traditional way of linear process development providing individual solutions for specific products, and to demonstrate the technological, economic and ecological superiority of truly „designing“ processes by application of advanced chemical and engineering knowledge. The SYNFLOW concept is based on the definition of generic challenges with industrial relevance, represented by Case Studies provided by the industrial consortium members. Catalyst development, studies of the underlying chemical target transformations (synthetic methodology), tailored reaction engineering, conceptual process design and process evaluation interact closely in order to substantiate the SYNFLOW vision. Its success will be demonstrated on a relevant production scale as a reference for the entire European Chemical Industry. The SYNFLOW consortium brings together major industrial producers from the Pharmaceuticals, Fine Chemicals and Intermediates sectors, providers of process technology and technical catalyst supply. A number of high-ranked academic partners ensures the availability of comprehensive expertise for the suggested Case Studies. Dissemination of the results is guaranteed by the participation of DECHEMA and Britest. SYNFLOW pres
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Plastics Recycling from and for home appliances, toys and textile' (PRecycling) targeting Horizon Europe.

assistant: **Abstract**

As it is addressed by the European Plastics Strategy (European Green Deal & Circular Economy Action Plan 2.0), new methods to reliably calculate, verify and report the recycled content in products need to be developed, boosting the increase of recycled content in everyday products against the use of virgin materials. However, measuring the recycled content is complex, requiring product tracing to the production source. PRecycling aims to develop an easy-to-use methodology for sorting, sampling, tracing and recycling plastic waste streams, including detection and separation of legacy additives, along with standard analysis procedures for both plastic waste materials and recyclates (secondary raw materials) in order to produce consistently high quality, safe-to-use recyclates based on their degradation degree and added-value products with predicted lifetime. Smart tracing via digital systems will be developed in parallel, to ensure the quality and safety of reused materials, targeting a sustainable, transparent and functional Circular Economy Model for the recycling market. The environmental and financial viability of PRecycling solutions will be assessed throughout life cycle and cost analysis in order to reach competitive prices of recycled products. The above will be demonstrated, producing (I) home appliances components, (II) toys/learning resources, and (III) 100% recycled textile, starting from the same sector recyclates and different European regions. However, the proposed methodology in PRecycling could be adapted by many other sectors, i.e. packaging, vehicles, and electric/electronic equipment, triggering significant societal impact apart from commercial and industrial interest. Demonstration activities will serve as part of a community awareness initiative, sho
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Identification by isotopes of human provenancing' (IDIS) under Seventh Framework.

assistant: **Objectives**

Isotope ratios from light and heavy elements are used in provenancing studies in ecology, archaeology and forensic sciences to track the origin and movements of humans and animals. The isotopic composition in human and animal tissues, acquired through dietary intake has been shown to have a general correlation with the isotopic composition of the environment (i.e. drinking water, soil, pollution). In forensic sciences isotopic methods, mostly on light elements, have been recently applied to track the place of origin and recent movements of present-day humans in murder cases and in relation to terrorism. Used as forensic intelligence, the isotopic data has been combined with DNA to aid identification of murder victims. Despite the potential of the isotopic methods their application is still limited and the huge potential of combining multiple isotopic systems to provide provenance information is almost unrecognized. This proposal therefore aims to validate a multi-isotopic approach by combining isotopic ratios of both light and heavy elements. In this proposal we will measure H-O-C-N-S-Sr-Pb isotope ratios in human tissues, such as hair, teeth, bones and organs from human volunteers and from samples taken from autopsies in The Netherlands to validate the multi-isotope technique. The human isotopic data will be correlated with environmental isotopic data, such as drinking water, soil, street dust, etc. available from data bases and from samples collected around the country. After the validation of the multi-isotope method, we will apply the multi-isotopic technique on 3-5 blind studies. These studies are murder cases already solved by the NFI. This will allow us to determine the resolution of the multi-isotope method. Later the method will be applied to 3-5 unknown cases.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Scientific Approach to Finding Indicators of and REsponses to Radicalisation'.

assistant: **Concept**

The goal of SAFIRE is to improve fundamental understanding of radicalisation processes and use this knowledge to develop principles to improve (the implementation) of interventions designed to prevent, halt and reverse radicalisation. SAFIRE will develop a process model of radicalisation, describing the process from moderation to extremism, based on a non-linear dynamic systems approach and a typology of radical groups. This is an innovative approach that has not been explicitly applied to this area up until now. Principles regarding interventions will be developed in close concert with the models, and will be applied in a longitudinal, empirical study. Important aspects of radicalisation that will also be addressed are: the relationship between national culture and radicalisation, radicalisation on the Internet, and defining observable indicators of the radicalisation process. The main deliverable is a CD containing on one hand a detailed description of the work done in SAFIRE and on the other an interactive, accessible overview of the project designed for quick, user-friendly accessibility to the main points. Envisaged end-users are policy makers, researchers in the field of radicalisation and professionals who work with high-risk individuals. The results of this project will increase the understanding of both conceptual aspects of radicalisation (e.g. the psycho-social dynamics of radical groups and individuals), and practical characteristics and modus operandi of radical groups (e.g. recruitment techniques). In addition, the results will increase understanding of field efforts and interventions – when, why and how they work – thus helping focus the allocation of resources and the implementation of interventions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'EUROPEAN DIGITAL UNIVERCITY - RESEARCH AND INNOVATION WITH AND FOR SOCIETY' (EDUC-SHARE) under Horizon 2020.

assistant: **Objectives**

At a time when we are coping a series of societal challenges there is an urgent need for a fully-implemented European Research Area allowing free circulation of knowledge, involving societal actors in the whole research and innovation process in order to better align its objectives with the values, needs and expectations of society.Through EDUC-SHARE, the European Digital UniverCity (EDUC) ambitions to turn its Alliance into a fully integrated university which meets all its missions (education, research and innovation at the European scale), that will give full importance to European citizens’ participation to identify and solve current and future challenges in an Open-Science-oriented approach, while promoting EU values and fundamental rights. The EDUC-SHARE project aims to deepen ongoing transformation and institutional changes of both the EDUC university members and the alliance as a whole, based on their own identified needs with an Open-Science-oriented evolution of practices.As part of its deployment, EDUC-SHARE will identify barriers at the institutional, local, national or European levels that will be reported to the relevant authorities in order to lower them for achieving a full integration of its proposed actions at the alliance or inter-alliance level. The EDUC alliance will then serve as a model of implemented European Research Area (ERA) and European Higher Education Area (EHEA) by creating a favourable, inclusive, environment interconnecting research and innovation ecosystems of its university members to speed up technology transfer taking into account citizens' concerns in policy making.


**Keywords:** key global challenges, citizen engagement, open science, responsible research and innovation, career development, HRS4R, knowledge and innovation transfe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Standardisation and Communication of Sustainable Energy Asset Evaluation Framework' in the context of a Horizon 2020 call.

assistant: **Objectives**

The main barriers to finance of Sustainable Energy Assets (SEA) projects – namely energy efficiency, demand response, distributed renewable energy generation and electricity storage – are: 1) project valuation difficulties; 2) difficulties in project optimisation; 3) a communication gap between contractors and investors leading to a lack of trust. Today, protocols and tools exist for project valuation, but they are used separately, in different ways by different investors or contractors. Therefore, SEA projects are valuated on a one-off basis, without any standardisation. The SEAF project will significantly lower the entry barriers to finance for small to medium projects, through combining existing tools and protocols, namely Joule Assets’ market valuation tool, the risk assessment methodology from insurance company HSB and the Investor Confidence Project’s energy performance protocols. These three service tools will be integrated into an all-in-one, easy to use, single source valuation and risk assessment framework, which aims to: 1) Facilitate and support an intensive stakeholder engagement process; 2) Provide independent valuation and optimisation for SEA projects according to up-to-date energy market data; 3) Standardise energy efficiency valuation criteria for easy comparability with other similar projects; 4) Enable initial risk assessment at much lower cost and with less administrative effort; 5) Facilitate the matchmaking between investors and contractors; 6) Lay the foundation for robust exploitation. In addition to its demonstration with a large network of investors and contractors, SEAF seeks to enable investments of €10-15m and primary energy savings of 18-45 GWh/a over the course of its duration. Through its unique combination of services, SEAF will specifi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Solving the TP-AGB STAR Conundrum: a KEY to Galaxy Evolution' (STARKEY), addressing dissemination and exploitation.

assistant: **Impact**

Models of the Thermally Pulsing Asymptotic Giant Branch (TP-AGB) stellar evolutionary phase play a critical role across astrophysics, from the chemical composition of meteorites belonging to the pre-solar nebula up to galaxy evolution in the high-redshift Universe. In spite of its importance, the modelling of TP-AGB  is still affected by large uncertainties that propagate into the field of extragalactic astronomy, degrading the predicting power of current population synthesis models of galaxies. The major goal of this proposal is to remedy this persistent condition of uncertainty and controversy. The solution to the TP-AGB star conundrum will be provided by a new approach, which stands on the optimised integration of a) state-of-the-art theoretical tools to account for the complex physics of TP-AGB stars (evolution, nucleosynthesis, pulsation, winds, dust formation, etc.), and b) exceptionally high-quality observations of resolved TP-AGB stellar populations in stars clusters and nearby galaxies (Magellanic Clouds, M31, dwarf galaxies up to 4 Mpc) with reliable measurements of their star formation histories. We will adopt a global calibration method, in which TP-AGB evolution models are required to simultaneously reproduce a set of well-defined observational constraints (distributions of luminosities, colours, pulsation periods, dust mass-loss rates, expansion velocities of dusty envelopes, etc.). This project will deepen our understanding of TP-AGB physics profoundly, and provide wide-spread community benefits as well. We will publicly release well-tested and reliable ``TP-AGB products'', including stellar tracks, isochrones in all photometric systems, and chemical yields for both gas and dust. Eventually these products will be embedded in the stellar population synthes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Semi-Artificial Photosynthesis with Wired Enzymes' under Horizon 2020.

assistant: **Concept**

Nature has been harnessing solar energy to drive endergonic life-sustaining reactions such as photosynthesis for billions of years. However, the overall biological processes are inefficient despite the evolution of efficient enzymes for carrying out specific reactions. Currently, there is an urgent need to develop superior strategies for the large scale conversion of solar energy into a renewable chemical fuel through artificial photosynthesis, which uses the same fundamental science as natural photosynthesis. Here we integrate the strengths of both natural and artificial photosynthesis to explore novel pathways for efficient solar-to-chemical conversion, which are otherwise inaccessible to either field alone.In aim 1, we develop advanced materials and strategies for the rational integration of photosynthetic enzymes into photoelectrochemical cells. A platform will be established in which enzymes can be artificially coupled to light absorbers, and also be wired together to perform novel chemical reactions.In aim 2, we adapt advanced analytical techniques, including scanning electrochemical microscopy and time-resolved spectroscopy, to gain mechanistic insights into the nature, extent, and mechanism of the enzyme-material interaction. This will aid rational cell design and shed light into reaction bottlenecks.In aim 3, we wire the enzyme-electrodes together in rational combinations to arrive at novel and efficient pathways for performing solar-to-fuel conversions. We will demonstrate the efficient coupling of solar energy harvesting with water oxidation and proton/carbon dioxide reduction.This integrated approach will lead the emergent field of semi-artificial photosynthesis beyond conventional solar fuels research. It will probe into the strengths and weaknesses of biol