RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Product-Service sYMBIOtic SYStems' (PSYMBIOSYS) under Horizon 2020.

assistant: **Objectives**

Product-service solutions are not a novelty for manufacturing domain, in particular for Europe. Services are becoming more and more not just an optional adjunct to products, but they are integral part of manufacturing industries’ offer, able to differentiate the product value proposition, to take a significant part of the revenue stream and even to substitute the traditional selling of products with more innovative service-oriented business models. There are still 5 main obstacles which are currently preventing service innovation to be pervasively adopted by all EU manufacturing industries, SMEs included:I. Products and Services : How to preserve the specific characteristics of product and services in a value chain, without creating isolated and not interconnected walled gardens?II. Design and Manufacturing: How to reconcile Real World and Digital World in PLM allowing multi-directional interoperability of the digital images of the same product between design-manufacturing? III. Knowledge and Sentiment: How to consider both professional knowledge and crowd sentiments, trying to mediate extreme product-push and market-pull positions?IV. Service-Oriented and Event-Driven: How to create a generic conceptual and implementation framework which could identify and implement the interoperability points between SOA and EDA in PLM value chain systems?V. Business and Innovation: How to reconcile current profitable and competitive product-oriented business models with more intangible, risky, service-oriented and Internet-based businesses?PSYMBIOSYS aims at improving the competitiveness of European Manufacturing industries by developing an innovative product-service engineering environment, symbolized by a five-pointed symbiosis star – design-production, product-service, knowledge-s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Experts Enablers in the Machinery Engineering Domain' (XPERTS).

assistant: **Innovation**

The main asset of European machinery builders and engineering companies is the knowledge existing in the companies, and more precisely, the design knowledge. However, there are several problems related to the capture of this design knowledge, its management and its loss. XPERTS aims at providing manufacturing and engineering companies with the means to manage the knowledge of experts effectively, considering the entire cycle of expertise acquisition by young engineers, the use of design knowledge in daily design activities and the avoidance of the loss of knowledge when experts leave an organisation.XPERTS will address three key research areas: the human interaction between experts and knowledge bases, knowledge formation from existing databases, and the use of knowledge as a component that makes it shareable.Objectives:XPERTS seeks to solve problems of machinery and engineering companies in the knowledge management domain by:Shortening the learning process for new employees;Providing a means by which to store the collective knowledge and lessons learnt about previous experiences;Providing a means by which to manage engineering knowledge and expertise;Determining agreed company standards and procedures for design.The main project target for industrial users is to reduce the time needed to adapt employees to their workplaces in the engineering field by a factor of 50%. An additional benefit will be the reuse of collective previous experience. A consequence will be the improvement of product quality by applying consistent standards and best practices in product design.The technical objective is to create a set of methods, guides and tools to represent, capture and accumulate the organisations/ engineering knowledge. Engineering rules, databases, standards, catalogues and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Control of RNA Polymerase II and Transcription Factors via IDRs'.

assistant: **Innovation**

RNA Polymerase II (Pol II) plays a pivotal role in human cellular function, carrying out the complex transcription process. A unique domain sits at the end of Pol II, the C-Terminal Domain (CTD), the phosphorylation of which offers a mechanism of interaction for transcription factors (TFs) that regulate the transcription process. The spatial organization of TFs around Pol II is moderated by the intrinsically disordered regions (IDRs) of the TFs and CTD, and high specificity is required to avoid disease causing defects. However, the exact mechanisms that maintain this environment, and their importance are still unknown. Here we suggest a method for determining crucial Pol II  TF interactions by relating electromagnetic imaging to computer simulations. Results will be able to delineate individual amino acids responsible for maintaining the spatial organization of the proteins in vitro. The simulation-based study will be leveraged to explore the tolerance of maintaining these interactions when encountered with different phosphorylation states of CTD. A proof-of-concept study is then described which will demonstrate an ability to actively target IDRs to stabilize the protein interactions. While the results here will be comprehensive for four TFs of interest (RECQL5, SCAF4, SCAF8, and the SOSS1 complex), the methodology can then be expanded to characterize a library of over 400 TFs. Such a project has the potential to not only further our understanding of CTDs function, but also pave a way for designing synthetic treatments that can regulate the transcription process.


**Keywords:** Condensates, RNA, Polymerase, Transcription, Factors, Nucleus, Low Complexity Domain, Intrinsically Disordered Region, Intrinsically Disordered Protein
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Metaphorical Narratives in Dementia Discourse'.

assistant: **Concept**

Research on dementia discourse has shown how our attitudes, views and words have a positive or negative influence on the well-being of People Living With Dementia (PLWD).  In 2013, Alzheimer Europe’s report underlined worrying ethical risks of metaphor use in dementia narratives, including stigmatisation, stereotyping and social exclusion. Yet we still do not have an adequate understanding of these potential risks and of the ethical responsibility needed when ‘metaphorical narratives’ (MNs), or metaphorical scenarios, are used in dementia discourse between scientists, journalists, caregivers and PLWD. This may increase risks of conflict and misunderstanding between these different social agents. It also hinders developing a responsible (i.e., respectful) use of MNs in dementia discourse, complying with the EU H2020 emphasis on Responsible Research and Innovation and healthy ageing.MeNDD develops an innovative interdisciplinary approach combining the experienced researcher’s historical-philosophical work on MNs in the biosciences across times and in responsible health communication with the supervisor’s new model of metaphor in discourse. It joins together a historical-epistemological approach, corpus research and informant analysis to build an innovative model of ‘social awareness of dementia MNs’. It shows how science, the media, professional caregivers and PLWD use two-major dementia MNs of ‘cognitive decline’ and ‘brain plasticity’ while balancing the potential risks and the ethical responsibility in differentiated, occasionally diverging ways. The model reveals the major patterns of social awareness of the two MNs in dementia discourse, highlighting potential risks of conflict and misunderstanding between the different groups. It is designed for utilisation in enhan
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Functionality of Oxide based devices under Electric-field: Towards Atomic-resolution Operando Nanoscopy' (FOXON).

assistant: **Concept**

Understanding oxygen dynamics is a key to superior device performance in emergent oxide electronics. So far it is an unrealized dream to correlate electrical behavior and atomic structure during device operation. Here, I envision bridging the gap between theoretical models and experimental reality. Recent advances in microelectromechanical systems (MEMS) chips for in situ transmission electron microscopy (TEM) are opening exciting new avenues in nanoscale research. The capability to perform current-voltage measurements while simultaneously analyzing the corresponding structural, chemical or even electronic structure changes during the operation of an electronic device would be a major breakthrough for nanoelectronics. Controlled electric field studies would enable an unprecedented way to investigate metal-oxide functional devices by using a lab-on-a-chip approach. I propose this project based upon own groundbreaking work on (i) how to electrically contact and operate an electron transparent lamella device fabricated from a metal-insulator-metal (MIM) structure (Ultramicroscopy 181 (2017) 144-149) and (ii) the design of a novel MEMS-based chip for in situ electrical biasing. FOXON will provide a platform for atomic scale operando investigations of oxide thin film and interface switching phenomena of MIM devices under electrical bias inside a microscope. My scientific endeavor will establish a group to develop beyond state-of-the-art operando TEM of MIM structured devices and tackle open questions in the field of oxide electronics. My scientific mission incorporates (a) studies of switching processes in oxide devices and (b) a comprehensive understanding of the atomic-level mechanisms that lead to tunable physical properties including dynamics of oxygen vacancies and stab
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Theoretical study of static and frequency-dependent magneto-optical properties' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Research objectives and content Aims of this project are the theoretical development, computational implementation and application of Coupled Cluster Response approaches for accurate, gauge-invariant, determinations of magneto-optical properties, in particular for the CC method hierarchy CCS, CC2, CCSD, CC3. In order to achieve gauge invariance of the computed properties and improve basis set convergence, the possibility of using atomic orbital basis sets explicilty dependent on the magnetic field - the so-called GIAO - would be implemented. Combining integral-driven techniques with field-dependent orbitals, these approaches would be applicable to molecules of real interest in spectroscopic experiments. Training content (objective, benefit and expected impact) The CC approach for molecular properties is among the most promising presently in the literature. The implementation of CC response functions with GIAO will allow the calculation of magnetically induced molecular properties, with levels of accuracy unachievable with other methods currently available. It is firmly believed that accurate theoretical calculations play a fundamental role for the correct interpretation of the information extracted from the extremely complex magneto-optical experiments. This project will give the applicant the possibility to gain fundamental experience in the field of electronic structure determinations, in particular on theoretical and computational aspects of magneto-optics, response functions and gauge invariant calculations of magnetic properties.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Properties of the s-layer-like domains present in cell surface proteins of clostridium thermocellum' under Fourth Framework.

assistant: **Concept**

Research objectives and content Several exocellular proteins of Clostridium thermocellum, a thermophilic Gram-positive cellulolytic bacterium possess a carboxy-terminal triplicated sequence which shows similarity to bacterial surface layer proteins. This sequence was named SLH domain (for S-layer homology) and is involved in the attachment of proteins to the cell surface. An objective of this project is to identify the sites of interaction between SLH domains and the cell envelope. Therefore, comparitive in vitro binding studies of SLH domains with purified and biochemically characterized compartments of the cell envelope of Clostridium thermocellum will be undertaken. Proteins interacting with SLH domains will be purified and characterized. To study the binding specificity of SLH domains in vivo, fusion proteins of SLH domains with a reporter protein will be produced and localized in an appropriate Bacillus strain. Training content (objective, benefit and expected impact) The objective is to learn new techniques in protein chemistry, e.g. analysis of protein-protein interactions, in addition to some special techniques in molecular biology. Those methods are very important for my future work in research and education in France or Germany. Links with industry / industrial relevance (22) The commercialization of the results of this project, e.g. new techniques for immobilization of proteins will be consulted with WISSTRANS GmbH, Goettingen in collaboration with Prof. Dr. Gerhard Gottschalk.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Living with Difference in Europe - Making Communities out of Strangers in an era of super-mobility and super-diversity' (LIVEDIFFERENCE) under Seventh Framework.

assistant: **Objectives**

We are witnessing unprecedented levels of mobility (within and beyond the European Union) and population change. In this context, how we develop the capacity to live with difference is the key question of the 21st century. It is this fundamental research question which this proposal addresses (an issue that is particularly pertinent given rising levels of insecurity generated by post 9/11 terrorism and the current global financial crisis). This will be achieved by the generation of a new body of information and understanding about the extent and nature of everyday encounters with difference through five inter-linked projects, each collecting original empirical data in the UK and Poland. My vision is to advance the theorization of meaningful contact by using this data about spatial practices of encounter and intersectionality to shed new light on mostly unevidenced interdisciplinary theories of cosmopolitanism; and to develop further an innovative social topographic approach for transcending conventional comparative research perspectives by producing a sophisticated model of the complex webs of connection across the research locations, integrating the findings from a post-colonial and post-communist state. I will develop new horizons in methodological practice through the development of biographical timelines, and audio diaries to capture qualitative longitudinal data; video-elicitation of encounters with difference; and radical spatial experiments to create meaningful contact. The findings will provide an integrated evidence base about everyday understandings of difference and spatial practices of encounter that will inform, and nuance, European policies and strategies for living with difference. This programme will be unique internationally and will open up new directi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Enhancing innovation management capacity of SMEs in Republic of Srpska' under Horizon 2020.

assistant: **Concept**

This action relates to Horizon 2020 topic Innovation in SMEs under Other actions (Specific activities in the context of innovation support (H2020), in particularly the component: “Enhancing the innovation management capacity of SMEs” in the Enterprise Europe Network. The main aim of the project is: Enhanced growth and profitability of 16 SMEs in RS through provision of specialized innovation support services by EUNORS Network partners.Specific objectives: - Enhanced innovation management capacity of 15 companies within 12 months in Republic of Srpska.- Provide key account management support for 1 successful applicants of SME InstrumentAs identified by both COSME and Horizon programs, in Europe, and more specifically geographic area covered by EUNORS, SMEs face a number of internal and external constraints, particularly “lack of financial resources” and “inability to manage innovation processes efficiently and effectively”.  To tackle these constraints, EUNROS will focus on providing customized EIMC expert support to SMEs in our target area, to a predefined number of beneficiaries with high potential for growth and internationalization. Additionally, EUNORS will work with SMEs in order to support them in the process of applying for SME Instrument (under H2020 Programme).Minimum number of service packages will be 16, from which 15 Enhancing innovation management capacity (EIMC) and 1 Key Account Management (KAM) package for beneficiaries of SME Instrument, FTI and FET-OPEN during 2019.


**Keywords:** Small and medium enterprise, innovation, research, entrepreneurship, technology, transfer,  knowhow
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Linking the development and implementation of technologies in nursing care'.

assistant: **Objectives**

With a rapidly aging population and a growing shortage of healthcare workers, digital technologies, such as robots, are essential for transforming healthcare. Nurses, the largest group in the healthcare workforce, are key to implementing these technologies. However, up to 80% of technologies fail to be fully implemented in the workplace due to insufficient involvement of end-users in the technology development and implementation process. LinkinCare aims to bridge this gap by aligning the needs of patients and nurses with technology development and implementation. This project will: (i) explore the needs of nurses and patients to co-design robotic functions that integrate seamlessly into nursing workflows; (ii) identify barriers and facilitators to robot implementation and develop tailored strategies to ensure successful integration in healthcare settings; and (iii) evaluate the cost-effectiveness of robot implementation by assessing outcomes such as acceptability, adoption, feasibility, impact on staff workload, patient experiences, and costs. LinkinCare will draw on interdisciplinary expertise from nursing science, robotics, implementation science, social science, and health economics, with a specific focus on compatibility with existing hospital systems and workflows. By collaborating closely with nurses, patients, and the industry partner Welbo (a robot supplier), this approach will ensure that the co-designed robotic functions are fit-for-purpose and suitable for practical use by both patients and nurses. Moreover, promoting needs-driven and cost-effective technological innovations will provide long-term societal benefits by sustaining the workforce and reducing costs. Additionally, the extensive multidisciplinary training in research and transferable skills provide