RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Multi-Dimensional Study of non Abelian Topological States of Matter'.

assistant: **Concept**

Non-abelian topological states of matter are of great interest in condensed matter physics,both due to their extraordinary fundamental properties and to their possible use for quantumcomputation. The insensitivity of their topological characteristics to disorder, noise,and interaction with the environment may lead to realization of quantum computers withvery long coherence times. The realization of a quantum computer ranks among the foremostoutstanding problems in physics, particularly in light of the revolutionary rewardsthe achievement of this goal promises.The proposed theoretical study is multi-dimensional. On the methodological side themulti-dimensionality is in the breadth of the studies we discuss, ranging all the way fromphenomenology to mathematical physics. We will aim at detailed understanding of presentand future experimental results. We will analyze experimental setups designed to identify,characterize and manipulate non-abelian states. And we will propose and classify novelnon-abelian states. On the concrete side, the multi-dimensionality is literal. The systemswe consider include quantum dots, one dimensional quantum wires, two dimensional planarsystems, and surfaces of three dimensional systems.Our proposal starts with Majorana fermions in systems where spin-orbit coupling, Zeemanfields and proximity coupling to superconductivity are at play. It continues with “edgeanyons”, non-abelian quasiparticles residing on edges of abelian Quantum Hall states. Itends with open issues in the physics of the Quantum Hall Effect.We expect that this study will result in clear schemes for unquestionable experimentalidentification of Majorana fermions, new predictions for more of their measurable consequences,understanding of the feasibility of fractionalized phases in qu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Integrated Platform for the European Research Infrastructure ON Cultural Heritage' (2014-2020).

assistant: **Concept**

IPERION CH aims to establish the unique pan-European research infrastructure in Heritage Science by integrating national world-class facilities at research centres, universities and museums. The cross-disciplinary consortium of 23 partners (from 12 Member States and the US) offers access to instruments, methodologies and data for advancing knowledge and innovation in the conservation and restoration of cultural heritage. Fourth in a line of successful projects (CHARISMA-FP7, Eu-ARTECH-FP6 and LabS-TECH network-FP5), IPERION CH widens trans-national access by adding new providers with new expertise and instruments to the three existing complementary platforms ARCHLAB, FIXLAB and MOLAB. The quality of access services will be improved through joint research activities focused on development of new advanced diagnostic techniques and (with DARIAH ERIC) tools for storing and sharing scientific cultural heritage data.Networking activities will (a) promote innovation through technology transfer and dynamic involvement of SMEs; (b) improve access procedures by setting up a coordinated and integrated approach for harmonising and enhancing interoperability among the facilities; (c) identify future scientific challenges, best practices and protocols for measurements; (d) optimise the use of digital tools in Heritage Science. To advance the international role of EU cultural heritage research, IPERION CH will generate social and cultural innovation by training a new generation of researchers and professionals and by worldwide dissemination and communication to diverse audiences. To ensure long-term sustainability, the advanced community of IPERION CH will work towards inclusion in the new ESFRI Roadmap and constitution of a RI with its own EU legal entity (e.g. ERIC). Synergies with
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Coupling dynamic population immunity profiles and host behaviours to arboviral spread' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Arboviruses infect millions of people each year, however, mechanisms that drive viral emergence and maintenance remain largely unknown. A combination of host factors (e.g., human mobility), mosquito factors (e.g., abundance) and viral factors (e.g., transmissibility) interconnect to drive spread. Further, for endemic arboviruses, complex patterns of population immunity, built up over many years, appear key to the emergence of particular lineages. To disentangle the contribution of these different drivers, we need detailed data from the same pathogen system over a long time period from the same location. In addition, we need new methods, which can integrate these different data sources and allow appropriate mechanistic inferences.In this project, I will use the most globally prevalent arbovirus, dengue virus, as a case study. I will focus on Thailand where all four dengue serotypes have circulated endemically for decades and excellent long-term data and isolates exist, to address two fundamental questions:i) How do population-level patterns of immunity evolve over time and what is their impact on strain dynamics? I will use mechanistic models applied to historic serotype-specific case data to reconstruct the evolving immune profile of the population and explore the impact of immunity on viral diversity using sequences from archived isolates from each year over a 50-year period.ii) How do human behaviors, vector densities interact with immunity to dictate spread? I will work with geolocated full genome sequences from across Thailand and use detailed data on how people move, their contact patterns, their immunity profiles and mosquito distributions to study competing hypotheses of how arboviruses spread. I will compare the key drivers of dengue spread with that found for o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Elucidation of the evolution of post-transcriptional regulation by characterizing the cnidarian microRNA pathway' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Over the past decade small RNAs such as microRNAs (miRNAs) and small interfering RNAs (siRNAs) have been shown to carry pivotal roles in post-transcriptional regulation and genome protection and to play an important part in various physiological processes in animals. miRNAs can be found in a very wide range of animals yet their functions were studied almost exclusively in members of the Bilateria such as insects, nematodes and vertebrates. Hence studying their function in representatives of non-bilaterian phyla such as Cnidaria (sea anemones, corals, hydras and jellyfish) is crucial for understanding the evolution of miRNAs in animals and can provide important insights into their roles in the ancient ancestor of Cnidaria and Bilateria. The sea anemone Nematostella vectensis is an excellent model for such a study since it can be grown in large numbers throughout its life cycle in the lab and because well-established genetic manipulation techniques are available for this species. Our preliminary results indicate that miRNAs in Nematostella frequently have a nearly perfect match to their messenger RNA (mRNA) targets, resulting in cleavage of the target. This mode of action is common for plant miRNAs, but is very rare in Bilateria. This finding together with my recent discovery of a Nematostella homolog of HYL1, a protein involved in miRNA biogenesis in plants, raises the exciting possibility that the miRNA pathway existed in the common ancestor of plants and animals.  Here I suggest to bring together an array of advanced biochemical and genetic methods such as gene knockdown, transgenesis, high throughput sequencing and immunoprecipitation in order to obtain - for the first time - a deep understanding of the biogenesis and mechanism of action of small RNAs in Cnidaria. Thi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Performance-based Innovation Rewards'.

assistant: **Innovation**

REWARD will open up new horizons in complementing the international intellectual property rights (IPR) system. The project's ambitious output is an ethically and legally sound performance-based reward mechanism for pharmaceutical innovation, which complements the existing patent regime, yet mitigates its considerable disadvantages for the global poor.The current IPR system impedes access to life-saving medicines for the poor in two main ways. First, high prices for pharmaceutical innovations are required to recoup research and development costs through time-limited patent protection. Whilst high price levels maintain incentives for pharmaceutical innovation, they price new medicines beyond the range of the poor creating an accessibility problem. At the same time, diseases that burden the poor are often not worthy of investment for pharmaceutical innovators, creating an availability problem ('neglected diseases').Many international research groups are working on IPR reform plans based on performance-based rewards for pharmaceutical innovation. However, their efforts are disparate and lacking a guiding vision. REWARD will use world-class ethics research as the steering force to determine which performance-based reward mechanism for pharmaceutical innovation is the most promising. In an interdisciplinary collaboration of ethicists, lawyers, economists, and statisticians, with experts in medicine, science and technology policy and gender studies the selected mechanism will be tested in a developed and a developing country.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Active dendrites and cortical associations' (ActiveCortex) under Horizon 2020.

assistant: **Objectives**

Converging studies from psychophysics in humans to single-cell recordings in monkeys and rodents indicate that most important cognitive processes depend on both feed-forward and feedback information interacting in the brain. Intriguingly, feedback to early cortical processing stages appears to play a causal role in these processes. Despite the central nature of this fact to understanding brain cognition, there is still no mechanistic explanation as to how this information could be so pivotal and what events take place that might be decisive. In this research program, we will test the hypothesis that the extraordinary performance of the cortex derives from an associative mechanism built into the basic neuronal unit: the pyramidal cell. The hypothesis is based on two important facts: (1) feedback information is conveyed predominantly to layer 1 and (2) the apical tuft dendrites that are the major recipient of this feedback information are highly electrogenic.The research program is divided in to several workpackages to systematically investigate the hypothesis at every level. As a whole, we will investigate the causal link between intrinsic cellular activity and behaviour. To do this we will use eletrophysiological and optical techniques to record and influence cell the intrinsic properties of cells (in particular dendritic activity) in vivo and in vitro in rodents. In vivo experiments will have a specific focus on context driven behaviour and in vitro experiments on the impact of long-range (feedback-carrying) fibers on cell activity. The study will also focus on synaptic plasticity at the interface of feedback information and dendritic electrogenesis, namely synapses on to the tuft dendrite of pyramidal neurons. The proposed program will not only address a long-standing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'European Centre for Risk Management and Safe Innovation in Nanomaterials  Nanotechnologies' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

A significant challenge to ensuring sustainable production and use of nanotechnologies is to understand safety and health risks of the technology and its end-products, and to implement practical strategies to manage these risks. Knowledge is growing rapidly, but effective use of this knowledge for risk management is lagging behind. We therefore need to bridge the gap between knowledge on hazard and risk, and ‘fit-for-purpose’ risk management tools and strategies supported by measurement and control methods. EC4SafeNano will bridge this gap in an efficient and sustainable way by setting up an independent, science-based, managed Centre (hub) linked with several networks (spokes) to act at the interface between research organisations, industry, regulatory bodies, and civil society. The objectives are to: 1) understand the needs of all stakeholders along the innovation value chain for nanotechnologies, ensuring safer, marketable, regulated and accepted long-lived products; 2) identify the resources and capabilities available to address these needs, and evaluate the capacity to provide technical solutions and actions; 3) build, test and benchmark a range of services, based on selected resources that answer stakeholder needs across the innovation value chain; 4) develop mechanisms and operating procedures to facilitate periodic updating of the “needs and resources” mapping and of the service provision; 5) develop networking activities aiming to share, benchmark and promote the EC4SafeNano services thereby enhancing and harmonizing the overall expertise, at EU level and beyond; and 6) develop governance rules and a strategic plan to prepare for self-sufficient operation beyond the project lifetime. The main outcome is the definition of a legal entity with operating procedures,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Multipurpose dynamically reconfigurable platform for intensive and flexible hetereogeneous processing : A technology breakthrough for Embedded Computing' (MORPHEUS) under Sixth Framework.

assistant: **Objectives**

The large-scale deployment of Embedded Systems, through Cooperating Objects for example, is raising new demanding requirements in terms of computing performance, cost-efficient development, low power, functional flexibility & sustainability. This results in an increasing complexity of the platforms & an enlarging design productivity gap: current solutions are out of breath while current development & programming tools do not support the time-to-market needs.MORPHEUS copes with these challenges by developing a global solution based on a modular SOC platform providing the disruptive technology of embedded dynamically reconfigurable computing completed by a software (SW) oriented design flow. These Soft Hardware (HW)" architectures will enable huge computing density improvements (GOPS / Watt) by a factor of x100, reuse capabilities by x5, flexibility by more than 100 and time to market divided by 2 thanks to a convenient programming toolset.MORPHEUS ambitions are also to establish the European foundation for a new concept of flexible "domain focused platforms", positioned between general purpose flexible HW and general purpose processors.This will be achieved within a 3-years project providing:- A modular silicon demonstrator composed of complementary run-time reconfigurable building blocks to address the different types of application requirements- The corresponding integrated design flow supporting the fast exploration of HW and SW alternatives- The suitability & efficiency will be validated by a set of complementary test cases.The dissemination through silicon offer & supporting tools (baseline for further commercial products) will be completed by specific training & broad information to address the necessary cultural change.This will be performed by:- A consortium wher
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Olsztyn Science Days Researchers Night 2008' to be submitted under Seventh Framework.

assistant: **Abstract**

The Researchers Night 2008 is planned to be held in Olsztyn the capital of  Warmia and Mazury Region on 26th September 2008, as a closing event of the 6th Olsztyn Days of Science. In 2007, the Olsztyn Days of Science were attended by over 30,000 people. The team of 34 high level representatives of  different local institutions will be involved in organisation of that event and lead by experienced Professor from the University of Warmia and Mazury in Olsztyn, the only one state university in the region. The  project's objective is to bring the general public closer to the profile of a scientist and to popularise research, innovation and knowledge based economy. Special attention is paid to young people living in villages, small towns - as the region is rural and less favourite area. In order to attain this objective, apart from demonstrations, study trips, visits to laboratories, exhibitions and other forms of direct participation, broad cooperation with the local mass media and Internet use; we want to prepare some touring exhibitions, competitions and presentations of educational films for different age groups. Communities will have better access to our activities through Internet: by blogs run by scientists and by co-editing of newly created WikiEncyclopaedia of Warmia and Mazury, by astronomical observations via Internet, by special radio and TV programmes. In addition transport to Olsztyn from villages will be provided by free of charge coaches. The countrywide photography competition called “The Researcher’s Work” will be organised. The concert “Polish Flute Music” performed by university professor, WikiEncyclopaedia as well as  short documentary film “A Scholar and Research Work - a Profile of a Young Scholar” foreseen for the Night will be recorded and delivered
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Healthy Ageing Research Centre' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The major goal of this proposal is to upgrade the research potential of research groups at the Medical University of Lodz investigating various aspects of healthy ageing and constituting already established Healthy Aging Research Centre. Major areas of research cover a wide spectrum of topics related to ageing: novel approaches to improve well being in the elderly,  pathogenesis and prevention of neurodegenerative, respiratory,  cardiovascular and   kidney diseases of the old age and molecular basis of ageing.  HARC has been conceived to upgrade and enhance  MUL  research capacity through several strategic objectives: 1) to reinforce and consolidate already existing  cooperation between HARC and 15 European partners; 2) to stimulate innovation with properly protected intellectual rights by exchange of know-how and creating new links with industry (SMEs); 3) to develop state- of- the- art research infrastructure in synergy with the structural funds intervention; 4) to attract researchers with international experience to work in our centre; 5) to promote international knowledge exchange through workshops and conferences; 6) to promote HARC and raise the awareness of healthy ageing within the scientific community, industry and the general public; 7) to contribute to the solution of the problems of age-related comorbidities in less privileged region of Central Poland by exchanging knowledge with international experts and cooperating with regional authorities 8) to increase the participation of the HARC researchers in the EU FP7 and other activities (Joint Programming, Innovation Partnership on Healthy Ageing, ERA-Net).