RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Biobank Standardisation and Harmonisation for Research Excellence in the European Union' to be submitted under Seventh Framework.

assistant: **Abstract**

Given contemporary understanding of the complexity of the causal architecture of common chronic diseases, the next stage of bioclinical scientific progress will depend critically on large-scale pooled analyses of high quality data from many biobanks and bioclinical studies. Such analyses will only be possible if we are able to harmonise and standardise the collection, storage, and management of data and bio-samples across biobanking studies. Recent consortium-based meta-analyses of genome-wide association studies (GWAS) have clearly demonstrated that it is possible to pool and analyse genomic data with broad indicators of disease status. But if health care science is to move quickly towards the exciting goals that have been envisaged for public health, clinical science, and personalised medicine a far greater challenge must now be overcome. That is, the standardization and harmonization of data and key measures of life-style, social circumstances and environment, as well as critical sub-components of the phenotypes associated with common complex diseases. This is the mission of BioSHaRE-EU.BioSHaRE-EU will work hand-in-hand with BBMRI (Biobanking and Bio-molecular Resources Research Infrastructure) and P3G (Public Population Project in Genomics), to build directly on extensive precursor work in the field of harmonisation and standardisation. The project will deliver tools to harmonize phenotypes of complex diseases, as well as lifestyle and environmental factors. In addition, it provides statistical methods and biostatistical tools for meta-analysis of large scale studies. These tools and methods will be developed and implemented in five large partner-biobanks: HUNT, KORA, LifeGene, LifeLines, UK-biobank. BioSHaRE-EU will also implement these in additional disease conso
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Bio-based functional materials from engineered self-assembling peptides' (BASE).

assistant: **Innovation**

The BASE-STREP aims at advancing the science and technology of sustainable and functional materials. Specifically it targets innovative nano-coatings for plastics, metals and ceramic objects, exploiting the self- assembly capabilities of short (< 25) am ino-acid sequences (=peptides) in industrially relevant applications. Self- assembly is a method of spontaneous organisation of molecules into higher order structures and defined by set boundary conditions (e.g. pH, T, etc).This addresses the need for wate r based coating solutions beyond plastics and explores principles of nature for supramolecuar structure formation at various surfaces. These ambitions require a work programme addressing the challenges facing peptide based nano-coatings in terms of their b io-technological engineering at a cost of < 300 Euro /kg and their functional performance validation in selected self-assembled nano-coatings. The workplan covers: 1 .Laboratory solid-phase synthesis of known peptides and their evaluation 2.Experimental biosynthetic production of two peptides at laboratory (1-3L) scale and the development of efficient scale-up protocols 3.Exploring the coating capacity of tailored peptides for various substrates and environmental conditions. 4.Biotechnical production and scaling up the production of one peptide to 100 L 5.Functionality evaluation of a specific peptide for selected multi-sectorial applications targeted by the industrial partners. 6.Either production at 1000 L scale (aiming at kg quantities), or production of a second peptide in g to hg quantities to allow larger scale performance evaluation of nano-coatings on selected substrates 7.A sustainability study to assess the environmental, economic and societal impact of these novel applications. BASE brings toget her a dive
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'From Polymer Intercalation in Lamellar hosts to Colloidal Inorganic Dispersion in Polymers : Hybrid Ionomeric Membranes for Application in Medium Temperature Electrochemical Devices' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

Our objectives are the development of thermally stable (to 180 C) protonic conducting membranes (o>10 2 Scm 1 ) based on hybrid inorganic organic systems. These are formed by the association of protonic conducting polymers and protonic conducting inorganic materials. The latter are layered solids which can be broken down into nanoscale building blocks by intercalation and exfoliation. These composites can be divided into:  conventional microscale composites,  intercalated and  exfoliated nanocomposites, and the continuum between the three classes will be explored. Functionalities conferring protonic conductivity will be introduced both onto the thermostable polymer and the inorganic layers by chemical modification including techniques such as grafting and topotactic exchange. The partner laboratories are experienced in the manipulation of two dimensional inorganic materials, and in the conception and development of new methods for the modification of layered solids. Other of the partner laboratories have many years experience in the chemical modification of polymers, and an industrial participant will assure membrane scaling up aspects and, eventually, manufacture. The materials and membranes will be characterised by a full range of chemical, thermal, spectroscopic, electrical and textural techniques which are available in the partner laboratories. No proton exchange membrane is currently commercially available for use at such temperatures. Rapid application in electrochemical devices for energy conversion and in electrochemical reactors is therefore foreseen. The partnership includes a research institute and an industry who have complementary expertise in the areas of electrode design, and fuel cell development and manufacture. These two groups will optimise membrane e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'CONGESTION MANAGEMENT STRATEGIES AND METHODS IN URBAN SITES' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

COSMOS addresses the problem of traffic congestion caused by incidents or over-saturation of the road network in urban areas with traffic signal control systems. Its central aim is to test and demonstrate congestion and incident management (CIM) strategies. To this end, the project will refine existing concepts for urban incident and congestion detection and, on the basis of the plans, develop detailed CIM and rerouting strategies for integration with on-line network signal control.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Collaborative Robotics for Assembly and Kitting in Smart Manufacturing' (ColRobot).

assistant: **Concept**

Manufacturing competitiveness depends largely on its productivity, flexibility and agility to react to market demands. Robots are a key element to achieve such competitiveness, especially if they are able to collaborate with humans in a shared workspace in the shop-floor, creating a co-working partnership. The paradigm for robot usage has changed from an idea in which robots work with complete autonomy to a scenario in which robots collaborate with humans. This means taking the best of each partner, human and robot, by exploring the cognitive and dexterity capabilities of humans (focus on value-added tasks) and the capacity of robots to produce repetitive work and provide assistance. ColRobot combines cutting-edge European robot technology and end-user requirements for assembly processes to create an integrated system for collaborative robotics in which a mobile manipulator acts as a “third hand” by delivering kits, tools, parts, and holding work pieces while the operator works on it. Humans will cognitively and physically interact with ColRobot robots using gestures, touch commands and demonstrations. The robot will be able to navigate autonomously in the factory floor to pick up the required parts and tools, and prepare kits for assembly. A safety system that pushes the limits of standardization in collaborative robotics supervises the process. The technology readiness level (TRL) will be increased by means of continuous iterative real world testing (performance, usability, relevance in manufacturing), validation and improvement. Two use cases in automobile and aerospace industry will be implemented and validated in real world operational environments. The ColRobot vision and the consortium competences in technology transfer will allow to reduce the technological inno
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Cost effective and environmentally sound dismantling of obsolete vessels', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

Ship recycling market is certainly one of increasing growth but also one with growing concerns about environmental safety, health and welfare matters. At the end of this decade, some 4.000 ships with an aggregate gross tonnage of 24 million are expected to be recycled. These figures warrant a thoroughly structured approach to the ship recycling issue by the maritime industry as a whole. This research project aims to: -Develop innovative dismantling and recycling procedures consisting of optimal design of a prototype ship dismantling site, and optimisation of ship breaking facilities and dismantling processes with respect to environmental and energy issues, cost, as well as occupationally hazards concerns. The above will also be applied to cases concerning basic improvement of already operational ship breaking yards, which may be active in full or partial dismantling.- Develop a Decision Support System (DSS) for the ship breaking industry, which will be released free of charge to all stakeholders worldwide. The DSS will take into consideration the existing capacity and dismantling methodology of a given ship breaker, the type and the particular characteristics of the dismantling ship, and diverse third parties reports, and it will outline the dismantling process in an environmentally sound, cost and energy effective way, taking into consideration the health and safety of the workers. It is estimated that the implementation of the DSS will lead to a reduction of manufacturing costs by 20%-30%.- Validate the proposed tools and methodologies through a real case study. The larger Turkish ship-breaker will first improve its facilities and modify its infrastructure and dismantling processes according to the outcomes of the project.Then, through a real case of a particular vess
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Neural Mechanisms of Learning and Memory' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The two conferences (Perturbation" and "Representation" of memory) have clearly defined and parallel integrative themes and objectives, each leading to a logical culmination of the Neural Mechanisms of Learning and Memory series. The first conference focuses on the experimental analysis of amnesia across species, including human disorders such as Alzheimer's disease. This focus on human amnesia is a new, but appropriate theme at this stage in the Series, which examines possible clinical applications of work reviewed in previous Euroconferences, as well as the added theoretical inspiration that derives from the study of patients. The cross-species analysis in this first meeting is essential for investigating the utility of animal models of amnesia, in particular, of transgenic manipulations, which seek to reproduce some of the key neuropathology of Alzheimer's disease. Technological significance derives from the use of such animals to assess the efficacy of forthcoming neuroprotective and neuropharmacological modes of treatment.The second meeting (on "Representation") focuses on the various ways in which different forms of memory are represented in the brain, using computational, cellular, molecular, neurophysiological and neuropsychological approaches in different model systems to unravel the mechanistic substrate of the memory trace. Particular emphasis will be placed in this second conference on relating more abstract and correlarive approaches to understanding memory (rather than the interventionist strategy inherent in the study of memory perturbation), in order to provide synergy between level of representation and analysis. We aim to relate levels of analysis such as computational modelling with a comparative analysis of the patterning of activity in the brain bas
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Renewable energy: best practice projects yearbook '00' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

The main objective of the Renewable Energy:Best Practice Projects Yearbook'00, will be to highlight the benefits of renewable energy technologies and encourage co-operation between industries by proving the technological and economical viability of the technologies described. Therefore this project will compile and promote information about the evolution of the renewable energy sector and of the best renewable energy projects undertaken within the European Union and Norway during the period 1997-2000.This project aims to provide an overview of some European renewable energy projects that can be considered to be best practice because of the results obtained and the introduction of innovative technologies or new commercial applications. This project will provide energy stakeholders with a better knowledge of the current market situation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Organ-on-a-chip Drug screenIng device to tArget braiN diseAse' to be submitted under Horizon 2020.

assistant: **Abstract**

The commitment to drug development for brain pathologies is experiencing a fast rate decreasing, a critical situation in a worldwide scenario where the number of patients affected by brain pathologies like Alzheimer’s (AD) or Parkinson’s (PD) disease are expected to greatly increase in the next decades. One critical point is that the development of new drugs is a three-phase process that currently requires 10-15 years and investment of 1-3 billion euros against a failure rate of about 99.6% for AD new drugs. The reasons of this discouraging scenario are multifaceted, but an important percentage of failure depends on weak quality of biological target validation assays, mainly due to the presence of the blood-brain barrier and the complexity of brain physiology that make challenging brain disease modelling. Hence, it is particularly crucial to implement an innovative, reliable in vitro cell model able to predict the potential of a new drug to cross the blood-brain barrier and effectively target the brain.DIANA (Organ-on-a-chip Drug screenIng device to tArget braiN disease) project aims to perform the technical and commercial feasibility of the integrated stand-alone BBB-brain model in-vitro, Chip4D Brain, based on patented organ on chip technology, providing the basis for a new generation of innovative devices. DIANA will be run by a consortium between Politecnico di Milano and an industrial partner, Neuro-Zone srl (Contract Research Organization – CRO - specialized in R&D for drug development in brain diseases for pharma) combining a solid technological expertise and an in-depth knowledge of the market.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Controlling conscious visual perception with light'.

assistant: **Objectives**

Imposing structure and interpretation on the multitude of sensory input we collect constantly through our senses is a primordial aspect of brain functioning. When scanning our surroundings we automatically segregate the visual scene into objects versus background. Although seemingly happening without any effort, the underlying computations performed by the brain are massive. Perceiving ambiguous figures exemplifies this complexity clearly. In case of the famous Rubin Face-Vase illusion we can perceive either faces or vases as figures against a background. Moreover we are able to consciously switch between percepts.Previous studies in the non-human primate have shown that already at the very early stages of visual processing neurons respond differently when stimulated by part of the visual scene belonging to an object than to the background. It is proposed that feedback connections from higher visual areas drive this figure-background modulation, but currently no technologies exist to examine this hypothesis adequately in the primate brain.Recently, Heimel (NIN) discovered the same figure-background effect in the visual cortex of the mouse. The possibility to easily manipulate neuronal activity in mice by illuminating the cortex will enable me to examine the function of feedback connections during figure-background modulation, a process also important for conscious vision.After thorough mapping of single and laminar response properties of V1 neurons in a figure-ground modulation paradigm, I will chart its network, i.e. characterize the information flow from V1 to higher areas, in real-time and with single cell resolution by means of two-photon calcium imaging. Both protocols are available and ready-to-use at the NIN. Finally, while recording single/laminar neural activit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Brain monitoring with information technology: an open, internet based, transnational infrastructure for health care technology assessment in brain injury (BRAIN IT)' (1998-2002) under Fifth Framework.

assistant: **Objectives**

The Brain IT network is an open transactional consortium of clinicians, scientists, Sees and large scale industry using computer and internet based technology to raise standards for multi-centre collaboration on methods for monitoring and treating patients with traumatic brain injury (www.brainit.gla.ac.uk/brainit). We aim to improve the hardware and software infrastructure to raise the open standards for multi-centre data collection and data validation and to broaden access to the Brain IT database; improve the coordination and long term funding prospects by restructuring the consortium on a country by country basis; disseminate to interested bodies the utility and cost-efficiency of the Brain IT network as an essential service for implementing multi-centre collaborative research and for measuring, maintaining and raising standards of treating patients with traumatic brain injury.