RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Damage cascades in neurological disorders: studies with imaging techniques' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

Fellowships (3,6,12 month) available for PhD and MDPhD students interested in studies on mechanisms involved in CNS damage and repair plasticity at the Graduate School of Medical Neurosciences at the University Hospital Charite, Humboldt University Berlin. The program is supported by the German Research Council DFG in the graduate college program (GRK 238) and focuses on Damage processes in the Central Nervous System: Studies with imaging methods" Applicants should be enrolled in a PhD or MD/PhD Program and have a background in Biology, Biochemistry, Physiology, Pharmacology, Molecular Biology, Medicine, Veterinary Medicine, Psychology or Neurosciences with an interest in Medical Neurosciences. Diseases of interest: Disturbances of blood brain barrier (I.E. Blasig), stroke and ischemia (U. Dirnagl, A. Villringer, G. Kempermann), multiple sclerosis (W. Brück, F. Zipp), regulation of microglial functions (C. Eder, H. Kettenmann), inflammation (U. Hanisch, U. Dirnagl), apoptosis (H. Ikonomidou, F. Zipp), temporal lobe epilepsy (U. Heinemann, T.N. Lehmann), Alzheimer (W. Müller, R. Nitsch), neuronal plasticity (R.Grantyn, U.Heinemann, T.N. Lehmann and R. Nitsch) Techniques: Macroscopic (MRT, fMRT, near infrared spectroscopy) and microscopic imaging techniques (Intrinsic optical signals, fluorescence imaging, one and two photon confocal microscopy), tracing techniques, histological and electron microscopic techniques, molecular biology, immunology and electrophysiological techniques. Generation of monoclonal antibodies. Studies are done in humans including intraoperative monitoring, rats and mice, slices of human and animal tissue, slice cultures and dissociated cultures. Studies on genetically modified animals are included. Special courses in Patch clamp and imaging techniq
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Simplifying Aerial Intelligence' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The drone industry faces several key challenges that prevent fast adoption of drone technology by mainstream enterprises. Amongst the main challenges are: complex drone regulations, high upfront cost and inadequate drone experience. In general, there is a real need for an end-to-end solution that would enable transforming data collected by drones into actionable aerial intelligence data.DroneGrid is an enterprise platform that enables 2D and 3D aerial inspections of assets using drones, including automated analysis of actionable data. Without needing their own drone fleet, our customers can easily access commercial drone technologies through DroneGrid to gather aerial intelligence and to easily integrate them into their existing processes. We take care of subcontracting the best drone operators for our clients. This enables enterprises to take better decisions, improve staff safety, increase asset efficiency and digitise their field information. DroneGrid consists of an industrial customer app/web platform, backend AI engine and an API layer that integrates with commercial drone software, various third-party services such as weather, regulatory, operational services and enterprise ERPs. On the other side, the platform can be used by certified and pre-approved drone pilots to perform missions on ordered customer operations. DroneGrid is already available in a functional commercial version in several markets: renewable energy (solar inspections), construction and mining. In order to enter additional industries, we need to improve 3D capabilities (vertical) as well as enhance its intelligence abilities. DroneGrid was established in August 2016 and is a pioneer developer of a smart cloud-based drone solution. DroneGrid has achieved significant growth and now has an internat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Marine Park Enhanced applications baseD on Use of integrated GNSS SErvices' in the context of a Seventh Framework call.

assistant: **Objectives**

Marine parks are areas which deserve an extremely accurate care of the ecosystem and as such are usually subject to severe restrictions applied to their end users, first of all leisure boats and local operators.Those restrictions are often different in different areas depending onto the level of threat that anthropogenic activities may exercise on local environment. As an example, in some areas boat transit may be fully prohibited, in others fishing and anchorage, in others night anchorage, etc.In order to limit and control the access to restricted areas, very often parks management organisations force users to request for a permit (e.g. daily or weekly, free of charge or not) without which the boats are not allowed to enter the marine park. In compliance with the different ways for accessing the park, also permits are different (e.g. transit and anchorage, shore fishing, sea fishing, scuba diving…).The main objectives of the Meduse Project can be summarised as follows:a)To develop a prototype service infrastructure for the delivery of location based services within restricted access maritime areas (parks, reserves) to the following customer categories:i.Institutional – Marine parks and restricted marine areas management institutions;ii.Private - Marine parks and restricted marine areas users (leisure boats);iii.Commercial – Commercial operators acting within restricted areas (e.g. cruise boats);iv.Law Enforcement – Maritime police authorities (Coast Guard).b)To demonstrate a subset of services and applications (with limited functionality) that shall be enabled by the service infrastructure for all the above listed customer categories;c)To analyse commercial sustainability of the service infrastructure in order to identify and characterise the critical mass of applicati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Markers and mechanisms of sensory disconnection' (StateDependentProces).

assistant: **Concept**

Sleep entails sensory disconnection, a state where external stimuli fail to elicit a meaningful behavioral response and do not affect perceptual awareness. While during NREM sleep and anesthesia thalamocortical neurons are bistable and the thalamus may not relay sensory signals effectively to the cortex, disconnection persists throughout REM sleep with its wake-like activity, as well as during other physiological and pathological states. This proposal seeks to reveal the markers and mechanisms of sensory disconnection and determine to what extent sleep and cognitive factors bring about similar disconnection. I hypothesize that sensory disconnection is a result of neuromodulatory changes, leading to a functional decoupling between early sensory cortex and higher order cortices. Specifically, reduced locus coeruleus-norepinephrine (LC-NE) activity may be a key mechanism, possibly affecting high-order thalamic nuclei and preventing ascending signals from effectively driving high-order cortical neurons. The proposed research will employ a combined approach in animal models (to experimentally dissect the underlying mechanisms and obtain detailed recordings of neuronal activity) and human studies (for carefully teasing apart cognitive factors, obtaining perceptual reports, and performing whole-brain imaging). I will address the following specific aims: (Aim1) identify markers of sensory incorporation vs. disconnection during physiological sleep/wake using auditory stimulation, (Aim2) reveal the underlying mechanisms by optogenetics (rodents) and pharmacological imaging (humans), and (Aim3) compare the effects of cognitive variables on sensory processing to those of vigilance states and the experimental manipulations. Understanding sensory disconnection will help reveal how st
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Dynamic Automatic Region Tracking (DART)' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Capturing nature’s most fleeting moments, such as a lemur leaping, a peregrine falcon striking, or dragonflies dueling over water, has always relied on a mix of skill and luck. It also demands extensive setup and long waits in harsh environments. With Dynamic Automatic Region Tracking (DART), these moments become routine and much easier to capture.DART revolutionizes nature cinematography with bioinspired algorithms and cutting-edge hardware. Using motorized mirrors to steer a camera’s view, it enables ultra-fast, high-resolution tracking of unpredictable subjects. The system integrates two cameras: a wide-angle search camera to detect action and a telephoto homing camera to capture it in stunning detail. Its bioinspired vision algorithm and controller enable low-latency, data-efficient, and energy-efficient continuous operation.This project will refine DART’s tracking algorithms and hardware controls to create a modular, plug-and-play solution for applications in agri-tech, environmental monitoring, industrial automation, entertainment, and wildlife documentary production. Building on our strong academic expertise in robotics and biomechanics, DART is now advancing toward real-world demonstrations with early partners. By capturing what once seemed unfilmable, DART opens new frontiers in motion analysis and visual storytelling.


**Keywords:** Visual tracking, bioinspired vision, nature documentary, motion capture, unmanned aerial system research
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'MicroRNA targeting to achieve Systemic Sclerosis Control and Prediction' to be submitted under Seventh Framework.

assistant: **Abstract**

Systemic Sclerosis (SSc) is a disfiguring disease with high mortality and morbidity, characterized by progressive and uncontrollable fibrosis of the skin and internal organs. There is no successful therapy for SSc resulting in a markedly shortened life expectancy, usually less that most cancers. Moreover, SSc diagnosis is very difficult in the early phase of the disease; consequently patient treatment is delayed until skin and/or internal organ involvement is evident and already irreversible. The pathology, therefore, presents an extreme need of both effective therapies and early diagnosis/prognosis markers, in order to treat SSc patients before the development of severe organ complications. The proposed project builds on the unique observation that plasmacytoid dendritic cells (pDC) are dysregulated in the early disease onset of SSc, due to an aberrant microRNA (miRNA) expression pattern. The aim of the proposal is to delineate the critical role of identified miRNAs in pDC dysregulation and translate it to clinical relevant instruments to prevent or treat SSc. Thanks to my scientific and technical expertise in the study of miRNAs and immune regulation, I will be able to dissect the aberrant mechanisms leading to pDC dysregulation via miRNA-regulated pathways. This will provide the basis to develop novel therapeutic approaches to dampen the immune alterations present in SSc and control the disease progression. Furthermore, the analysis of a unique cohort of preclinical SSc cohort present in Radstake’s group and its expertise in SSc field will allow me to identify miRNA profiles that predict the progression of early-SSc into definite SSc. The marriage between my own and Radstake’s group expertise will therefore create the perfect ground to open novel perspectives for a m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Role of ces in Lactococcus lactis membrane protein production'.

assistant: **Objectives**

The goal of this proposal is to elucidate the exact configuration and role of the 2-CS CesSR in L. lactis (stress) physiology. The ultimate aim of the work on L. lactis protein production is to develop the organism into a legitimate alternative host for the production of (medically relevant) membrane proteins. These objectives will be pursued through a project with four interconnected work packages (WPs): [WP1] The role of sRNA in membrane protein overproduction stress, will be determined studied the transcriptomes of MPs overproducing L.lactis strains obtained by RNA sequencing. [WP2] Unravel the regulon of cesFSR and the role of cesF in cesR activity. The effects of mutations in cesS, cesR as well as cesF on the response of L. lactis to MP overproduction will be examined through RNA sequencing. [WP3] The establishment of the roles of identified sRNAs in cesFSR-mediated stress response will be determined. For this purpose, a selection of the sRNAs positively identified in WP1 and WP2 will also be subjected to in-depth mutational analysis to uncover their regulatory roles. [WP4] The obtaining of L.lactis strains with improved MP production characteristics. These strains will be constructed according to the results of WP1, WP2 and WP3. Results from this proposal hold promise for further increasing MP overproduction capacity of L. lactis, solving some of the long-standing issues in this field of research, and for creating intellectual property rights for a high-tech small or medium-sized enterprise in the biotechnology/pharmaceutical field.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Priming in an aquatic ecosystem - Stream biofilms as hotspots for carbon cycling'.

assistant: **Concept**

Recent findings concerning the role of inland waters in global carbon cycling is currently having a major impact of the view of the global carbon cycle. These findings highlight inland waters - such as streams, rivers and lakes - as major sites of carbon cycling, implying that they must be considered in the context of climate change. Microbial degradation of organic carbon is a process that is central to carbon cycling in all ecosystems. In soils, microbial degradation of recalcitrant carbon is often controlled by the availability of labile carbon sources. This is linked to the priming effect (PE). Mounting evidence suggests that PE is also important in aquatic ecosystems but it has yet to be explicitly addressed. Biofilms are vital components of aquatic ecosystems. In stream biofilms, heterotrophic bacteria and algae coexist in close proximity, exposing the bacteria to both recalcitrant organic carbon of terrestrial origin and labile organic carbon from the algae. This could make stream biofilms hotspots for PE. In PRIMA, I propose an innovative effort cutting across aquatic and terrestrial ecosystems, spanning single-cell to ecosystem scales, and combining methods from biogeochemistry and molecular microbiology to study PE in stream biofilms. Carbon flux in stream biofilm microcosms and in ecosystem scale stream mesocosms will be measured to quantify PE and its implications for carbon cycling in streams. The mechanisms of PE will be addressed on single-cell and community scales using cutting edge methods, such as NanoSIMS and 454-sequencing. I am an experienced researcher trained in Norway and Sweden. In PRIMA, I seek to combine my existing skills with the unique expertise and facilities of Prof. Tom J. Battin at the University of Vienna.  The many conceptual and meth
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Boosting plant-Endophyte STability, compatibility and Performance Across ScaleS' to be submitted under Horizon 2020.

assistant: **Abstract**

We need to increase the crop yield while reducing pesticide and use of inorganic fertiliser to meet the challenges of world population growth and climate change. Plant endophytic microorganisms can improve plant yield and enhance plant tolerance to abiotic stress as well as to pathogens under experimental conditions, but these effects are often not sufficiently stable for practical application. How do we boost the stability and reliability of the positive effects of endophytes on plants? We need to understand the genetic basis of beneficial interactions between crops and endophytes and extent this basis exhibits phenotypic plasticity at all interaction levels from the cellular to the field environment. This requires increasing our knowledge of the molecular mechanisms underlying the effects of endophytes, including intra and inter-kingdom exchange and distribution of resources (nutrients), signalling and possibly regulation between and inside the partners, the mutual induced production of secondary metabolites and the environmental cues which influence crop-endophyte interactions. The genetic variation and its plasticity in host and microbe will be exploited in to establish crop breeding and inoculum production processes for boosting the establishment and stability of plant-microbe mutualisms to benefit crop development, stress tolerance, pathogen resistance and quality. In this project we will provide fundamental biological as well as practical knowledge about interactions between endophytes and plants. This improved understanding will pave the way for increased use of endophytes to improve sustainability and plant productivity in a reliable way. The participants in this project comprise many of the key institutions and industries working with these problems and provid
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Augmented Commerce, a game-changing augmented reality-based sales experience to disrupt the e-commerce industry' in the context of a Horizon 2020 call.

assistant: **Objectives**

Augment is a highly-promising French SME founded in 2011, which is in a position to disrupt the e-commerce market through a proprietary augmented reality (AR) solution targeting both sellers (Augment Sales App) and buyers (Augmented Shopper App).Recently introduced to the public eyes through the famous game Pokemon Go®, AR is also impacting the retail and e-commerce industries. Indeed, it allows consumers to use real-life spaces to virtually “try on” furniture, ultimately bridging the gap between digital and real worlds. The global augmented reality application in retail and e-commerce (a-commerce) is expected to reach $14 billion by 2020. From the customers standpoint, “the elephant in the room is price” (DigiCapital) of the AR technology acquisition. With its global approach, Augment will make such a technology affordable to the customers by generating models that can be mutualised and used with minor adjustments, whatever the manufacturer, the brand or the distributor.From the very beginning, Augment is an innovation-driven company which offers to the users the capability to simulate their products in 3D AR at scale in real-time in real environments, all from the convenience of their smartphones or tablets. Augment is supported by business angels, venture capitalists and national funding agencies. It has raised a total of 5.7M€, to develop its B2B and B2B2C Apps, allowing it to become one of the European AR leader.With the SME Instrument project, Augment ambitions to boost its own development to become a worldwide leader in a-commerce by 2020. The Phase 1 feasibility study aims to scale up the Deep Modelling 3D Generator to allow a swift expansion of its 3D models catalogue (a prerequisite to outpace competitors) and to release a detailed business plan based on marke