RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Critical queues and reflected stochastic processes' (CRITIQUEUE).

assistant: **Concept**

Our primary motivation stems from queueing theory, the branch of applied probability that deals with congestion phenomena. Congestion levels are typically nonnegative, which is why reflected stochastic processes arise naturally in queueing theory. Other applications of reflected stochastic processes are in the fields of branching processes and random graphs.We are particularly interested in critically-loaded queueing systems (close to 100% utilization), also referred to as queues in heavy traffic. Heavy-traffic analysis typically reduces complicated queueing processes to much simpler (reflected) limit processes or scaling limits. This makes the analysis of complex systems tractable, and from a mathematical point of view, these results are appealing since they can be made rigorous. Within the largebody of literature on heavy-traffic theory and critical stochastic processes, we launch two new research lines:(i) Time-dependent analysis through scaling limits.(ii) Dimensioning stochastic systems via refined scaling limits and optimization.Both research lines involve mathematical techniques that combine stochastic theory with asymptotic theory, complex analysis, functional analysis, and modern probabilistic methods. It will provide a platform enabling collaborations between researchers in pure and applied probability and researchers in performance analysis of queueing systems. This will particularly be the case at TU/e, the host institution, and atthe affiliated institution EURANDOM.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'High Energy Solar Particle Events foRecastIng and Analysis' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

HESPERIA will produce two novel operational forecasting tools based upon proven concepts (UMASEP, REleASE). At the same time it will advance our understanding of the physical mechanisms that result into high-energy solar particle events (SEPs) exploiting novel datasets (FERMI/LAT/GBM; PAMELA; AMS) and it will explore the possibility to incorporate the derived results into future innovative space weather services. In order to achieve these goals HESPERIA will exploit already available large datasets stored into databases such as the neutron monitor database (NMDB) and SEPServer that have been developed under FP7 projects from 2008 to 2013.The objectives of HESPERIA are:1) To develop two novel SEP forecasting systems based upon proven concepts.2) To develop SEP forecasting tools searching for electromagnetic proxies of the gamma-ray emission in order to predict large SEP events.3) To perform systematic exploitation of the novel high-energy gamma-ray observations of the FERMI mission together with in situ SEP measurements near 1 AU.4) To provide for the first time publicly available software to invert neutron monitor observations of relativistic SEPs to physical parameters that can be compared with the space-borne measurements at lower energies.5) To perform examination of currently unexploited tools (radio emission)6) To design recommendations for future SEP forecasting systems.The results will be openly accessible to the public through the dedicated web interface of HESPERIA and will further be posted in related servers such as NMDB and SEPServer. The HESPERIA consortium consists of 9 partners with complementary expertise covering all aspects of the project.  HESPERIA will also collaborate with a number of institutes and individuals from US and Russia, ensuring both the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Hip at what cost? How the human pelvis adapted to bipedalism and childbirth' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Evolutionary selective pressures have shaped the human skeleton for millions of years, contributing to its distinctiveness compared to other primates. Among all the elements of our skeleton that have undergone huge modification, arguably one of the most distinctive ones is the pelvis. The pelvis plays a pivotal role in reinforcing the skeleton against external forces during locomotion and as such, selection pressures have acted particularly on it. However, efficient bipedalism came at a cost, when balancing other selection pressures. As a result, the difficulty of childbirth has been constant during human evolution. Today, obstructed labour is the cause of 8% of maternal mortality. A deep analysis of the biosocial dynamics that act from birth to adulthood is fundamental for a complete understanding of pelvic anatomy. Such a developmental perspective on the pelvis anatomy is currently missing. RISEN aims to fill this gap by extensively exploring the mechanisms that lie behind pelvic development, unravelling how, when, and to what extent external influences - e.g., bipedalism, health status - affect adult bone morphology. Thanks to the proposed innovative and multidisciplinary methodology that leverages cutting-edge technologies and brings together biological and cultural data, RISEN (24 months, USA – 12 months, Italy) will produce a comprehensive investigation that will have a huge impact on contemporary society or public health issues related to women's lives. This international and interdisciplinary project will give the fellow a full background and foster scientific expertise to accomplish a project as ambitious as RISEN. This project responds to EU research priorities through the transfer of gained knowledge and partnerships development with leading experts. Not only
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'SYSTEMS THINKING FOR COMPREHENSIVE CITY EFFICIENT ENERGY PLANNING' under Seventh Framework.

assistant: **Concept**

The partners of the project are 3 cities with similar characteristics, experience and policies in specific sustainable use and production of energy and very ambitious carbon and energy reduction targets, aligned with Europe’s targets. In each city, initiatives to reduce energy inefficiency are already in place; however each of them has been aimed at a specific sector objective, while overlooking the impact that may be causing on other sectors. This is why all the stakeholders and city systems are considered so important when undertaking measures aimed at improving sustainability to make this an integral part of their urban planning in order to achieve best results in less time and will less cost.For this reason, these cities have decided to join together to improve efficiency along all the key aspects of their energy value chain, by applying smart city concepts in an integrated manner while learning from each other’s expertise and viewpoint in applying sustainable practices. The partners are experts on Energy (FSS, SANSEBASTIAN, TECNALIA and ACCIONA), ICT (BRISTOL, UNIBRISTOL and ARUP) and Mobility (FLORENCE, SPES and ATAF).To get the proposed objectives STEEP project will create a process model based on systems thinking for district energy master planning, which will be applied to 3 city districts to better understand the systems impacting upon energy use and interventions which can be taken to meet the ambitious energy and carbon targets. These models will be enriched and validated through open innovation methodologies applied with the stakeholders. The learning obtained from the process model for district energy master planning, then, will be applied at the definition of specific action plan (time line, the costs and pay-back periods) at city level. With the knowledg
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Bound residues and nitrofuran detection', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

The use of nitrofuran antibiotics in farm animals was banned in the EU because of their toxicity. Monitoring compliance with the ban by testing for residues of the parent drugs is ineffective, because they are rapidly metabolised in vivo, and their residues are unstable. Nitrofuran metabolism is complex, with extensive formation of stable, tissue-bound residues with relatively long tissue half lives. Mild acids (like the human stomach) release potentially toxic compounds from bound nitrofuran residues. This project will develop screening tests and a Reference Method for these compounds, to provide an effective tool f or surveillance and enforcement. Methods will be extensively validated according to current EU guidelines; will be used to measure the prevalence of the bound residues in a pan-European survey and to define the length of time for which illegal abuse can be detected. A project web site, a Consumer Awareness Forum, National Reference Laboratory Technology Transfer events and articles prepared for the consumer press will ensure maximum dissemination of the aims and findings of the work to end users; and an SME will develop novel, marketable products.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'HERIT4AGES: User-centric and data-driven retrofitting solutions for a resilient, energy-efficient, low-emission and inclusive cultural heritage.' (Herit4ages) under Horizon Europe.

assistant: **Objectives**

For decades, heritage buildings have been an example of resilience, but also low emissions and the core of our cities, towns and villages. A building that has no use or purpose is abandoned and lost. It is imperative to ensure their conservation and maintenance by making them accessible, affordable and easy to maintain but also habitable and that is only possible considering comfort as the main target. Heritage buildings represent an important part of our cultural identity. It is time to include them in the adaptation to a new social and energy model.  This project aims to demonstrate that it is possible to improve the overall performance of heritage buildings while preserving their architectural and cultural identity. Given that the spectrum of heritage buildings is very broad and those protection laws may allow for different levels of intervention; the project aims to develop a set of solutions that can be replicated in different parts of Europe. The idea seeks to solve the problem of lack of comfort experienced in many heritage buildings where in many cases either there is no heating/cooling system or the use of the existing one entails a significant economic expense due to the need to air-condition large volumes of air. Achieving acceptable levels of comfort is something that will not only benefit the health of the users but will also help to make these buildings attractive places to develop different uses and thus help to preserve them.  When we are faced with the energy rehabilitation of a heritage building in which we normally have construction elements with high thermal inertia, the most recommendable solutions to take advantage of this characteristic are usually to insulate the exterior with hygroscopic materials. Unfortunately, in many cases, this intervention
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Safety Intelligent Fisheries Product Traceability Management Throughout The Supply Chain', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

SAMANTHA aims at providing a system, which will enable the traceability of products, based on the ability to identify them uniquely at any point in the supply chain. The small and medium sized fisheries determine the size of a batch, which is identified uniquely thanks to a RFID tag containing the required information.For many European SMEs, and even more those included in coastal regions in some specific sectors like the fishing industry present in this consortium, it is of utmost importance to be able to control and manage effectively products and goods traceability throughout the supply chain, not only because they have to observe EC directives regarding certification of goods and consumers health, but also because those halfway points are the object of many black market activities which are definitely harmful both for the industry and consumers.SAMANTHA addresses the deserved resources management and control, accounting for an intelligent streamline of the traceability supply chain processes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Exploring the contribution of hypothalamic gliosis to the metabolic and reproductive complications of hypogonadism: Translational implications for obesity-induced male hypogonadism.'.

assistant: **Objectives**

Obesity is a worldwide epidemic and a serious public health threat since it greatly increases the risk of highly morbid chronic diseases, including type 2 diabetes, hypertension, cardiovascular disease, and many cancers. A growing body of literature has suggested that obesity is associated with hypogonadism, (defined in males as low levels of endogenous testosterone) a reproductive disorder that substantially elevates metabolic risk. The mechanisms linking reproductive function to metabolism are not fully understood, but emerging evidence from clinical and preclinical studies suggests the potential role of hypothalamic gliosis. Recent data support a model in which microglia (brain macrophages) and astrocytes mediate the effects of a Western-type diet to induce obesity, and that hypogonadism synergizes with an obesogenic diet to profoundly activate hypothalamic gliosis. In this context, we propose a multidisciplinary approach to unveil the potential role of hypothalamic gliosis as a central node linking metabolic dysregulation and reproductive dysfunction. The studies described herein will use astrocyte- and microglia-specific mouse models of increased or reduced inflammatory signaling to determine whether gliosis is proximal to hypogonadism, hypogonadism causes gliosis, or they establish a vicious cycle together. These studies will potentially provide cellular targets for new therapies to offset the long-term metabolic harm from hypogonadism and to improve reproductive function in obese patients. Beyond its translational value, the project will provide a solid foundation for the scientific career of the fellow and help her achieve the long-term goal of becoming an independent scientist.


**Keywords:** Reproductive health, obesity, hypogonadism, astrocytes, microglia, K
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'New approaches to characterise Schistosoma mansoni infections persisting despite mass drug administration' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Neglected tropical diseases affect over 1.4 billion people and cause a greater disease burden than HIV/AIDS. Despite extensive mass drug administration (MDA) schistosomiasis remains a major public health issue, with a socio-economic impact second only to malaria amongst parasites. I will evaluate novel strategies and new technologies to monitor the impact of MDA programmes, to identify threats to MDA effectiveness, and enhance control of schistosomiasis in sub-Saharan Africa.Specifically I will address five ambitious questions:1. What is the best way to monitor schistosome infections and drug efficacy?2. Has drug resistance been selected for?3. What is the potential for drug resistance to spread?4. What other factors drive transmission?5. What other factors affect parasite clearance?These aims are feasible through innovative interdisciplinary methods including a) state-of-the-art DNA-chip diagnostics, b) novel application of genetic analysis to differentiate surviving worms from juveniles, c) use of drug screening technology to measure in vitro drug susceptibility, providing the first quantifiable in vitro phenotype without using mammals, d) combination of molecular techniques with mathematical models to elucidate the potential spread of phenotypes and e) an unparalleled interdisciplinary approach deducing host effects in non-clearers.These methods and technologies have not previously been used to assess MDA effectiveness for any helminth infection. My pioneering research will enable a comparative assessment of how transmission is affected by untreated adults and pre-school children, individuals with heavy infections, coinfections, and drug coverage. This will elucidate optimal strategies to reduce transmission hotspots.My results will improve monitoring protocols and i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project '‘Filming’ excited state structural dynamics in photosynthesis and organic semiconductors' (StructDyn), addressing dissemination and exploitation.

assistant: **Impact**

I wish to record ‘atomic movies’ of the structural quantum response in photoexcited chromophores.The structure of molecules relaxes as a response to photoexcitation. Coherent atomic relocations are thought to be important in photosynthesis and they ‘wire’ together distant electronic systems on conjugated polymer chains. The structural details of such atomic motions remain today elusive, because experimental techniques to visualize them are simply not available.I will pioneer femtosecond time-resolved X-ray scattering at state-of-the-art European synchrotrons and free electron lasers to directly visualize the atomic details of such motions.The specific objectives of my challenging research plan are to measure the excited state structure of conjugated molecules; to film solvent structural dynamics on femtosecond time-scales; to directly visualize the coherent structural photoresponse of photosynthetic proteins and conjugated polymers; and to find out how nature uses structural dynamics for directed energy transport in photosynthesis.This research program builds on my strength in organic semiconductor photophysics and time-resolved X-ray scattering. I have pioneered a description of exciton energy transfer in conjugated polymers beyond the state-of-the-art and have mapped the complete photocycle of organic solar cells for the first time. Proving that I can successfully change research fields and produce high quality results, I have been the first to apply time-resolved wide angle X-ray scattering to the study of membrane protein structural dynamics.Femtosecond time-resolved X-ray scattering is a new generic approach with applications in physics, chemistry and biology. My work will open new horizons in quantum chemistry, photophysics, and structural biology.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Revealing the neural computations that distinguish imagination from reality' (MonitoringReality), addressing dissemination and exploitation.

assistant: **Impact**

Our brain is able to turn external signals coming into our senses into a vivid and coherent experience of reality. At the same time, our brain is also able to generate sensory experience in the absence of external signals via imagination. Contrary to our intuition, our experience of reality is not an objective reflection of the external world, since the brain has no direct access to that. Instead, what we perceive as reality is an inference that the brain makes about its own activity, which is both externally driven (by sensory input) and internally driven (by imagination). Recent research has shown that imagining something leads to similar patterns of brain activity as perceiving that same thing in reality. This raises the question; how does the brain determine whether activity represents reality or imagination? I hypothesize that to distinguish imagination and reality, the brain relies on a perceptual reality monitoring process where higher-order brain regions infer perceptual reality when sensory signals are strong enough and there is low cognitive control. I propose to test this idea by answering three complementary questions: (a) how does sensory processing influence reality judgements? (b) how does cognitive control influence reality judgements? and (c) how are different signals integrated and evaluated to form reality judgements?  To answer these questions, I will use a novel psychophysical paradigm to experimentally induce confusions between imagery and perception in healthy participants. I will precisely characterize neural processes during these confusions by combining state-of-the-art techniques (high-field fMRI, MEG and tRNS), with advanced computational methods (multivariate decoding and Bayesian modelling). The results of this project will increase our fun