RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Innovative high efficiency phase change fluid based heat engine' (UP-THERM), addressing dissemination and exploitation.

assistant: **Impact**

A simple and economic engine concept is proposed as an alternative to the conventional heat engine.The main innovative character of the project is determined by the conceptual approach toward technological solution of the challenging problems of heat engines with external heat supply. This approach includes the use of working fluids changing phase, with crucial benefits in terms of:•liquid working fluid, being incompressible, decreases remarkably dead volumes and their influence on the efficiency;•substantial reduction of the dead volume permits using of external heat exchangers and thus to solve the scale up problem;•heat transfer can be improved because of the boiling and condensation processes;•engines with liquid working fluid can be made much safer since in operation volume of gas/vapor phase is smaller whereas out of operation a high-pressure gas phase can be absent at all;Up-Therm engine will be assembled in a micro-CHP (3 kW) prototype, which will demonstrate that:•Up-THERM engine cost is much lower (< 500 €/kW) than other technologies (ICE, Stirlin, micro-turbine), thanks to its design simplicity;•Specific power (kg/kW) is in line with the other product;•Mainly for low power size the electrical efficiency of the innovative engine is incomparable. Making a comparison with the commercially available system with a power < 3 kW, the Up-THERM efficiency is almost double.The tangible outcomes of the Up-THERM project, available to SME partners for exploitation, are:1)Working fluid design for the thermal engine, with a proper characterization and performance evaluation.2)Engine executive design of Up-THERM unit, with an integrated control strategy. The Up-THERM unit has to achieve the following targets: Pel = 1 – 3 kW; Thermal efficiency = 35% at least; Maintenance int
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'THE SAFETY PHARMACOLOGY OF ARTEMISININS WHEN USED TO REVERSE PATHOPHYSIOLOGY OF MALARIA IN PREGNANCY'.

assistant: **Objectives**

Artemisinin based antimalarial drug combinations are recommended for the treatment of P.falciparum malaria infections throughout all malarial endemic areas of the world and in all populations, including women of child bearing age. The studies planned in this collaborative project are central to assessing the potential hazard posed by these drugs to the developing human foetus and thereby making evidence based recommendations on the risk:benefit of these drugs. Although clinical experience to date indicates the artemisinins to be safe, the area of reproductive toxicology demands special consideration. Data from the Chinese literature and our own studies confirm that the artemisinins are embryotoxic and potentially teratogenic in animal species at drug doses within the human therapeutic range.  Based on over ten years of investigating the pharmacology of these drugs we have developed a hypothesis which can explain these teratogenic effects. Our hypothesis is based on the generation of reactive oxygen species (ROS) from cleavage of the artemisinin peroxide bridge and consequent embryofoetal damage to key biological macromolecules. Our hypothesis draws on parallels with the metabolic activation and teratogenic effects of the other established teratogens such as phenytoin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Predicting single-cell ploidy from digital pathology images in pan-sarcoma' (SImPloidy) targeting Horizon Europe.

assistant: **Abstract**

Sarcomas are a diverse group of rare cancers that originate from mesenchymal tissues. The rarity and intrinsic genetic complexity of sarcoma have made it one of the most challenging tumours to diagnose and consequently, to treat. A key genetic characteristic of many sarcoma subtypes is aneuploidy. Aneuploidy is defined by losses and gains of chromosomes, and is a prognostic marker for a variety of sarcomas. Currently, tumour ploidy are most commonly estimated using copy number alteration calling software on whole-exome and whole-genome sequencing data. However, the unsatisfactory accuracy, economic costs, infrastructure requirements, lack of trained personnel in interpreting the results is still an impediment to global adoption of these techniques for routine use, particularly in less developed economies. The goal of this research is to develop a more accessible and more accurate approach for predicting tumour ploidy based on Hematoxylin and Eosin (H&E) stained whole slide images. The specific aims of the project are to 1) optimise a nucleus segmentation model for annotating sarcoma nuclei in H&E images, and predict tumour ploidy at single-nucleus level, 2) thoroughly validate image ploidy and systemically compare it with existing ploidy estimation methods, 3) evaluate the diagnostic and prognostic value of the image ploidy, and investigate its underlying biological mechanisms in pan-sarcoma.This work will be carried out at University College London and the Royal National Orthopaedic Hospital, under the supervision of Prof. Adrienne Flanagan and Dr. Nischalan Pillay. The host labs have collected and scanned whole slide images of more than 40 types of bone and soft tissue sarcomas from more than 8000 cases, of which 1,600 cases have paired WGS and transcriptome sequencin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Active manipulation of Biomolecules in microfluidic arrays' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

The proposed research deals with the problem of sorting and separating biomolecules using a microfluidic network of micron- or nanometre-sized channels. The flow in the network is driven by electrical potentials induced by electrodes placed at various node s of the network. We propose to carry out a comprehensive study (both analytical and computational) of the resulting electroosmotic flow (EOF) in the network in order to determine the channel configuration and the electric potential distribution required t o propel different sized molecules to exit through different outlet channels.The essentially flat velocity profile of EOF should provide higher resolution and much quicker process times than the traditional method of gel eletrophoretic separation. A novel feature that we are proposing is to employ slowly converging inlet channels (for reducing the entropic forces) and slowly diverging outlet channels (for ease of collecting the separated molecules). Our ultimate aim is to integrate the computational scheme we develop with micro-fabrication procedures to rapidly prototype custom-designed channel configurations for particular applications.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'European Education Connectivity Solution'.

assistant: **Innovation**

The EECS project brings together three European SMEs and three academic researchers in order to develop a prototype campus card management system that will serve the unique needs and requirements of European Higher Education Institutions.  EECS will recommend standards for campus card systems to the ISO and will build the prototype to the recommended standards in order to facilitate interoperability between campus card management systems across Europe.  The EECS project will give the participating SMEs access to trans-European research and development, which will deliver an interoperable card management system. The consortium will work with the European Campus Card Association (ECCA) to develop the most appropriate solution for European campuses, based on the unique needs of Higher Education institutions.   The EECS project will produce an integrated campus card solution, which will be exploited by the partner SMEs. This is a highly ambitious goal achievable through state of the art research and the careful partnering of Research and Technological Development (RTD) performers and SME partners. Typically, access to such research capability is confined to the multinational organizations. The EECS goals are, therefore, ideally suited to the Research for SMEs program.  The core technological ambitions of the project are to:  - Facilitate the interoperability of campus systems and basic functionalities, including the  transfer of student information and access to a range of fundamental campus services for  students.  - Develop an information transmission interface that will translate information stored on one campus card into a common format based on European standards.  - Facilitate the secure authentication of information transfer between educational institutions.   The pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'S-wake - assessment of wake vortex safety (S-WAKE)'.

assistant: **Concept**

The present S-Wake project aims to develop and apply tools for assessing appropriate (safe) wake vortex separation distances. There are two reasons for addressing the wake vortex safety issue in S-Wake. The first reason is that Airbus Industries (and Boeing) are planning the construction of a new very large transport aircraft, which potentially introduces a larger hazard for following aircraft than existing large aircraft. Secondly, with the present wake vortex separation rules, the major airports in Europe become increasingly congested. The S-Wake project addresses these issues by investigating the levels of wake vortex safety behind the projected new aircraft and by developing and applying a safety assessment methodology, based on a probabilistic approach. A large database with quantitative data for wake vortex encounters (based on one year Flight-Data-Recording data for aircraft arriving at a major European airport) will be collected and analysed for validating essential part of the S-Wake project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Towards an ERA in Industrial Biotechnology' (ERA-IB) targeting Sixth Framework.

assistant: **Abstract**

Industrial Biotechnology (IB) is the modern use and application of biotechnology for the sustainable processing and production of chemicals, materials and fuels. It uses enzymes and micro-organisms to make products in sectors such as chemistry, food and feed, paper and pulp, textiles and energy. This ERA-NET is a joint initiative of 17 research programme funding and/or management organisations of 12 countries with important initiatives in the field of IB. In all of the participating countries Industrial Biotechnology (IB) is recognized as a key technology for a sustainable chemical industry and society and of utmost importance for economic growth and innovation in Europe. IB, although already successfully established in some sectors, is still in its infancy. Therefore, more in-depth knowledge derived from both basic as well as applied research, is necessary to fully explore the wide range of possibilities. As national strategies and activities in this area are currently being developed and implemented, it is now the moment for effective coordination and cooperation in Europe. The partners of this ERA-IB committed themselves to enhanced cooperation and coordination in IB research funding and management policies. The structured work programme includes the development of dedicated procedures and systems for coordination and integration of national programmatic research activities, identification of important themes for new research programmes, and creation of (new) transnational managed research programmes (including joint calls for proposals). In selecting the most important research themes for these jointly managed research programmes, the ERA-IB closely cooperates with the European Technology Platform for Sustainable Chemistry and the European Federation for Biotechnolo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Boosting the discovery using τs in the ATLAS detector at the Large Hadron Collider' to be submitted under Horizon 2020.

assistant: **Abstract**

Almost ten years into the highly successful program both in ATLAS and CMS, our understanding of the Standard Model (SM) of particle physics has deepened.  Nonetheless, what lies beyond the SM remains one of the most urgent questions of physics in the 21st  century.   To  move forward, one must  think outside of the box and leap into uncharted waters.  Searches today are aiming at the high-energy frontier, while  low-mass resonances are mostly overlooked by the Large Hadron Collider (LHC). Consequently, far-reaching hints of new physics may silentlyhide in the data.  Motivated by numerous New Physics (NP) scenarios that often predict light states, such as extended Higgs sectors, axion physics, or dark sector models, among others, the PI will develop new techniques to search for low-mass resonances decaying into two collimated low-pT hadronic τ leptons. τs, being the heaviest,  third-generation leptons,  provide a unique experimental opportunity to search for low-lying states that would otherwise go undetected.  In particular,  novel methods to identify boosted hadronic τ+τ− pairs will be established.  These techniques will  then  be  used to  pave a new path towards discovery of low-mass resonances produced through various production modes.  As part of this proposal, the PI will also develop new trigger-level capabilities to further extend the reach of this program at Run-3.  As a former leader of the ATLAS Beyond the Standard Model physics group, and current leader of low-mass resonance searches, the PI is ideally positioned to establish a strong research team and take this project to completion, laying the groundwork for the discovery of new physics beyond the SM.


**Keywords:** ATLAS, Physics Beyond the Standard Model, Tau, Beyond the Standard Models Higgs Searches
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Exploring the physics of 3-dimensional topological insulators' (3-TOP) targeting Seventh Framework.

assistant: **Abstract**

Topological insulators constitute a novel class of materials where the topological details of the bulk band structure induce a robust surface state on the edges of the material. While transport data for 2-dimensional topological insulators have recently become available, experiments on their 3-dimensional counterparts are mainly limited to photoelectron spectroscopy. At the same time, a plethora of interesting novel physical phenomena have been predicted to occur in such systems.In this proposal, we sketch an approach to tackle the transport and magnetic properties of the surface states in these materials. This starts with high quality layer growth, using molecular beam epitaxy, of bulk layers of HgTe, Bi2Se3 and Bi2Te3, which are the prime candidates to show the novel physics expected in this field. The existence of the relevant surface states will be assessed spectroscopically, but from there on research will focus on fabricating and characterizing nanostructures designed to elucidate the transport and magnetic properties of the topological surfaces using electrical, optical and scanning probe techniques. Apart from a general characterization of the Dirac band structure of the surface states, research will focus on the predicted magnetic monopole-like response of the system to an electrical test charge. In addition, much effort will be devoted to contacting the surface state with superconducting and magnetic top layers, with the final aim of demonstrating Majorana fermion behavior. As a final benefit, growth of thin high quality thin Bi2Se3 or Bi2Te3 layers could allow for a demonstration of the (2-dimensional) quantum spin Hall effect at room temperature - offering a road map to dissipation-less transport for the semiconductor industry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Always-On Intelligent Sensing with the Spiking Neural Processor' (2021-2027), addressing dissemination and exploitation.

assistant: **Impact**

Over the last 5 years, the number of devices equipped with sensors has grown exponentially reaching 4 billion per year. In battery-powered devices such as phones, smartwatches, wireless earphones, & video doorbells, energy-efficient processing of the complex, continuous data coming out of multiple sensors is a critical problem. Innatera is a trailblazing semiconductor spin-off of the TU Delft & is bringing to the market neural processors. Our Spiking Neural Processor (SNP) is inspired by the way neurons function in our brain using a neural network with an inherent notion of time. At the sensor edge, SNP can deliver always-on pattern recognition functionalities in power & latency-sensitive applications via an innovative programmable architecture. It enables application-specific customers to implement immediately ready-to-use high-performance pattern recognition. SNP delivers market-leading differentiation with faster time-to-market & reduced development effort.


**Keywords:** neuromorphic processor ,signal processing, time-series processing,analog-mixed signal computational fabric,neural networks,sensor ,neural processor,accelerator,always-on sensing applications,pattern recognition,spiking neural networks
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The cosmic web from eROSITA and galaxy surveys synergy' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The cosmic web (CW) is a complex network of structures composed of galaxies, dark matter, and gas, formed of galaxy clusters connected by filaments. Low-mass groups and large-scale super-clusters have yet to find a place in the context of the CW. The best way to trace the CW is to use optical galaxy surveys to detect the filaments and X-ray data to detect the hot gas of clusters. The detection of groups and super-clusters requires high-sensitivity X-ray instruments due to the low density of their gas content and has so far been very difficult. The new X-ray telescope eROSITA has however produced X-ray data of unprecedented sensitivity, which allow the discovery of thousands of groups and hundreds of super-clusters. eROSITA opened for the first time the possibility for statistical studies of these structures in the context of the CW. My goal is to exploit the synergy between eROSITA and galaxy surveys to shine new light on the place that groups and super-clusters occupy in the CW. This study will improve our understanding of how filaments channel accretion onto groups and will show how a physical definition for super-clusters (whose definition has so far been empirical) can be achieved in the CW context. The study of the CW is entering a phase of increased interest thanks to recent wide-area galaxy surveys and new X-ray data. Investigations like this project are those that will pave the way for future experiments (e.g. Euclid, ATHENA). This research will provide a significant advancement to our understanding of the CW, structure formation, and galaxy evolution. With this research I will gain deep insight on how to integrate X-ray and optical data in the context of a large collaboration. This project will prepare me to better deal with the outcome expected from future gal