RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Advanced High-Order Simulation Methods for Industrial Applications'.

assistant: **Objectives**

The ASIMIA technical objectives aim to improve the predictive capabilities of current aerodynamic simulation tools in industry, based on Computational Fluid Dynamics (CFD), by applying High Order Methods (HOM) instead of current second order approximations.HOM for CFD has a strong potential towards higher reliability of the predicted results, leading to enhanced design process, lower costs and reduced time-to-market of challenging future designs.It is generally considered that HOM could form the next generation of industrial CFD tools, but the competitiveness and adequacy of the HOM approaches for CFD has still to be demonstrated for industrial applications. ASIMIA aims at removing some of the current limitations for high-fidelity industrial applications, leading to a new generation of CFD tools with a high level of efficiency and maturity. NUMECA, an innovative SME acting as CFD and multiphysics software developer is joining with the Center for Numerical Simulation of the School of Aeronautics at Universidad Polytecnica Madrid (UPM) and three Industrial Partners from three different sectors, Aviation with AIRBUS, Car Aerodynamics with McLAREN F1 and Industrial Appliance Industry with DYSON, to lead 5 doctorates towards innovative simulation methods and relevant industrial applications.In addition, ASIMIA will• consolidate a joint PhD training program to foster research in the areas of contemporary fluid dynamics and multiphysics numerical simulation•  improve the transfer of knowledge between academia, SME's and industry, establishing a long- term collaboration and dissemination strategy• enhance the preparation of highly trained and skilled young engineers to careers in the high-tech industries• enhance researchers career perspectives in numerical simulation, through
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Physiological function and potential therapeutic utility of the neuropeptide galanin in airway inflammation' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The results of studies of the physiological and pathophysiological effects of peptides have guided the development of two principal classes of therapeutic agents: small molecules able to block the action of peptide receptors and synthetic peptides mimicking the actions of endogenous molecules. Within this arena, the effects of neuropeptides on the central nervous system (CNS) have been studied intensively for more than 20 years, leading to several therapeutic products that are in clinical development. However, it is now clear, that the actions of neuropeptides are far more diverse than previously thought. Another area with great pharmacologic potential encompasses the peripheral actions of the neuropeptide galanin. Lately, galanin has been shown to exhibit potent anti-inflammatory action in the skin and recent data indicate that galanin is also involved in the physiology and the immune system of the airways. Consequently, we hypothesise that galanin is a crucial regulator of airway inflammation and vascular tone in the lung. We further propose that  galanin exerts its effects at different cellular levels within the pulmonary system. The aim of this study is to determine novel/specific functions and sites of action of galanin in the respiratory system and to evaluate the therapeutic potential of galanin on airway inflammation and hyperreactivity. To achieve these specific aims we will take a multidisciplinary approach, employing molecular and cell biology, pharmacology, in vivo animal model and clinical research. The outcomes of this study will precisely define the role of galanin in the respiratory system and may suggest novel therapeutic strategies for the control of asthma, chronic bronchitis or other inflammatory pulmonary disorders. The findings from this research m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Next Generation Modelling of Terrestrial Carbon Cycle by assimilation of in-situ campaigns and Earth Observations' in the context of a Horizon Europe call.

assistant: **Objectives**

The ability to evaluate EU's climate and sustainability targets is currently limited by challenges in monitoring ecosystem greenhouse gas (GHG) exchanges and other services in an accurate and timely manner. Important knowledge gaps concerning processes and drivers of GHG exchanges persist, that further hamper our predictive capabilities. The absence of coherent approaches to collect, interpret and integrate data on terrestrial GHG stocks and processes into predictive models limits the EU’s ability to monitor ecosystem services and thus to reach its climate ambitions, including the Paris Agreement of Climate Convention and European Green Deal.NextGenCarbon aims to develop a novel framework for advancing our understanding of the European GHG budget. To reach this goal, we will: 1) improve and enrich existing measurements on ecosystems; 2) assimilate these data into state-of-the-art modelling frameworks; 3) create seamless scenario prediction systems; and 4) provide guidance to policymakers on the magnitude, evolution of and future risks to GHG fluxes. Our exceptional multidisciplinary consortium links leading experts developing the next generation of ground and EO-driven observations, with several groups at the cutting edge of carbon cycle and land surface modelling, plus teams pushing the boundaries of data assimilation, complex system modelling, forest management and disturbance monitoring, land-use and GHG inventories, and communications. It also involves active engagement with diverse stakeholders, including landowners and managers, GHG exchange modelling community, international community related to environmental monitoring, climate policy support and GHG inventory experts, and policymakers. In doing so, NextGenCarbon will pave the way for high-accuracy and seamless
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'UNCHARTED: Understanding, Capturing and Fostering the Societal Value of Culture' (UNCHARTED) targeting Horizon 2020.

assistant: **Abstract**

In recent decades, with the growing emphasis on the creative economy, culture has tended to be increasingly seen in political circles under the exclusive lens of the economy and its contribution to it. To counteract this tendency, it is necessary to define the social values associated with culture on a different basis from the traditional one. The work focuses on the valuation practices of the actors involved in cultural life. In this respect, three areas and three types of fundamental actors in the value dynamics of culture are distinguished: the field of cultural participation, in which citizenship is the protagonist; the field of cultural production and heritage, where the professionals of creation and preservation are the ones who take the initiative; and the field of cultural administration, in which it is the experts and politicians who decide. The project takes these three areas and this basic typology of actors as a starting point to structure the study of the different aspects involved in this evaluative dynamic: the emergence of values, the configuration of a value order and the political impulse of values.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'TIGIT therapy for cancer treatment' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Treating tumors with immune-related therapies is one of the most exciting and promising advancements made in the past decade. Cancer immunotherapy drugs have captured nearly 50% of the overall oncology drugs market. TIGIT is an important checkpoint inhibitory receptor discovered by our group in 2009. It is constitutively expressed by various immune cells and its expression is further increased on tumor infiltrating lymphocytes (TILs). TIGIT recognizes two main ligands, PVR and Nectin2 that are highly expressed on various tumors. Blockage of TIGIT on TILs either alone or in combination with another checkpoint inhibitory receptor, PD-1, leads to increased T and Natural Killer (NK) cell activity in vitro and inhibited tumor growth in vivo. We developed 9 different anti-TIGIT mAbs during my BacNK ERC advanced grant and previously. In the POC grant TIGITtherapy, which already attracted interest from several bio pharma companies, I propose testing which of the 9 anti-TIGIT mAbs and TIGIT-Ig are able to antagonize TIGIT activity.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Tandem Catalysis: New Processes for Meta-Selective Functionalization of Arenes' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Catalytic C-H functionalization holds great promise as a tool to simplify the synthesis and modification of organic compounds. A complete set of C-H functionalization methodologies would allow the synthesis of most molecules of interest. Despite important advances in the last decades, major challenges remain, in particular, on how to control the regioselectivity of C-H activation amongst the many C-H bonds present in the molecule.The aim of the research activities detailed in this proposal is to develop a cascade process that will use CO2 as an invisible Directing Group leading to an array of novel direct meta-functionalization methodologies. Our new methodology will proceed through a multi-catalytic system where (a) CO2 is captured ortho to a group R, (b) a CO2H directed ortho-fuctionalization occurs, and (c) CO2 is removed leading to the product of meta-functionalization. Thus, this ground-breaking methodology will present enormous advantages respect to ‘traditional’ cross-couplings in terms of cost (cheaper starting materials), and waste generation (only water and carbon dioxide generated), becoming a remarkably greener approach to the synthesis of the important biaryl unit.Clearly, the development of a meta-selective C-H functionalization methodology with increased substrate scope would be highly desirable, improving the access to biaryl motifs, which are ubiquitous in natural products, pharmaceuticals and organic materials, offering a more direct, economic and significantly greener approach.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Advanced methanol fuel cells for vehicle propulsion (AMFC)' (AMFC).

assistant: **Concept**

Objectives and problems to be solved :A fuel cell system is promising for powering vehicles in order to increase the energy efficiency and reduce emissions. The current PEMFC technology is obstructed by high materials cost and lacking infrastructure for a suitable fuel. The strategy of this project is to develop cost-efficient polymer membranes for operation at >150°C. High CO tolerance at this temperature makes it possible to develop a simple and compact system. Moreover the high operational temperature allows a thermal integration of the fuel cell with the methanol reformer.Description of the work:The project aims at developing temperature-resistant polymer membranes and related technologies, including studies of the effect of fuel additives on the catalysts, methanol reforming at low temperatures, catalytic burning of fuel/exhaust for heat supply and exit-cleaning, fuel cell stack construction and thermal interfaces for integration of methanol reformer and fuel cell.Finally an integrated AMFC power system will be constructed and station-tested for demonstration and evaluation. Transnational efforts from European oil industry, vehicle manufacturing industry and fuel cell system production industry as well as well-qualified R&D groups will be made to ensure a success of the development.Expected Results and Exploitation Plans:An integrated system consisting of 5 kW stack, methanol reformer and burner will be constructed and tested. This novel concept of integration will make the fuel cell system compact, light, and energy efficient, efficient in cost and simple in construction and operation. High reliability, less maintenance and better transient response capacity will also be potential features of this technology. A fulfilment of the project objectives will sufficientl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'REplicable, interoperable, cross-sector solutions and Energy services for demand side FLEXibility markets' (REEFLEX).

assistant: **Innovation**

REEFLEX aims to generate niches of opportunities for new cross-sector energy services provided by SMEs and start-ups in demand side flexibility markets and to increase participation of energy consumers in demand side flexibility markets. The project develops a central interoperability platform and a catalogue of services with the capability of maximising distributed energy resources' flexibility while respecting the different end user profiles and needs along with the physical limitations of existing infrastructures. Additionally, the generation of a common operation market model together with AI-driven intelligence services and automation systems, enabled through the utilization of distributed ledger technologies for enhancing transparency and trust, will reduce market entry barriers and costs and achieve a higher participation from energy consumers. They will benefit from new revenues obtained through data and flexibility transactions, while enjoying innovative, personalized, data (intelligence)-driven services for smart, human-centric control of their assets in the frame of demand response or self-consumption.REEFLEX solutions, they will be demonstrated and cross-tested in 4 main demonstrators (Spain, Greece, Switzerland, Bulgaria) with different characteristics, allowing evaluation of their impact under alternative scenarios and integrating a variety of sectors, such as residential buildings, mobility, commercial establishments, industrial sites or data centres, among others. In addition, the services catalogue will be further replicated in three additional replicators across Europe to achieve wider coverage (Turkey, Portugal, Denmark) and adaptation, ending-up in a total of 7 countries for the whole project execution. These cross-tested demonstrators and additional
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Precision Lepton Flavour Conservation Tests in Kaon Decays' to be submitted under Seventh Framework.

assistant: **Abstract**

A unique and innovative test of a cornerstone principle of the Standard Model of particle physics, the Lepton Favour (LF) conservation, is proposed in the framework of the NA62 experiment at CERN. The search for nine decay modes of the charged kaon and the neutral pion forbidden in the Standard Model by LF conservation will be carried out at a record sensitivity of one part in a trillion. Such sensitivity will be achieved due to the uniquely intense kaon beam that will become available to the experiment in 2014, as well as a range of novel particle detection technologies employed. The collection of the LF violating decay candidates will take place in ""parasitic"" mode alongside main NA62 data taking, which guarantees the feasibility, high data quality and cost-effectiveness. The project will bridge a significant research gap that has developed due to the absence of dedicated LF projects in the kaon sector, in sharp contrast with B-meson, lepton and neutrinoless double beta decay experiments. Any observed LF violating process will unambiguously point to physical phenomena beyond the Standard Model description, and will thus represent a major discovery. The Standard Model extensions that will be probed include those involving heavy Majorana neutrinos and R-parity breaking supersymmetry. Entire classes of new physics models will be confirmed, rigorously constrained or eliminated.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Application of integrated sea-bottom exploration by hydro-acoustic methods: Forecast of marine aggregates resources in Lithuania'.

assistant: **Objectives**

The strategic objective of the project is to promote and adapt the state-of-the-art non-invasive hydro-acoustic marine floor research methods through the example of their implementation for marine sand aggregates exploration for beach nourishment purposes on strongly eroding East Baltic Sea coast. Progress in acoustic methods ensures good recognition and classification of the sea bottom surface and seabed morphology as well as its geological structure. Modern hydro-acoustic methods together with precise positioning system provide possibility of constant digital registration of the sea bottom development due to human impact or natural processes. Such approach allows predicting the sediment dynamics changes in the near-shore zone and evaluate coast development and possible erosion threat, which is extremely important for the actual and future costal management. The interpretations based on the physical seabed sampling determined that the major part of the seabed surface remains unrecognised but specified only by the means of interpolation. Modern acoustic equipment ensures complete seafloor covering and therefore maximum accurate and realistic results can be obtained.The original idea of the research project is to recognize and map the old (drowned) beach sediments of the offshore zone and evaluate their suitability for the actual beach nourishment activities. The complex geological history of the Baltic Sea has determined, that the prospecting of marine aggregates suitable for the beach protection/replenishment works is rather complicated business. During water level changes and shoreline migrations in Late Glacial and Early Holocene Pleistocene sediments were eroded and re-deposited. Namely former beach sediments should be studied as the 1st rank potential source materi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Strengthening European Food Chain Sustainability by Quality and Procurement Policy' (Strength2Food) under Horizon 2020.

assistant: **Objectives**

Strength2Food is a 5-year, €6.9 million project to improve the effectiveness of EU food quality schemes (FQS), public sector food procurement (PSFP) and to stimulate Short Food Supply Chains (SFSC) through research, innovation and demonstration activities. Our 30-partner consortium representing 11 EU and 4 non-EU countries combines leading academic, communication, SME and stakeholder organisations to ensure a multi-actor approach. It will undertake case study-based quantitative research to measure economic, environmental and social impacts of FQS, PSFP and SFSC. The impact of PSFP policies on balanced nutrition in schools will also be assessed. Primary research will be complemented by advanced econometric analysis of existing datasets to determine impacts of FQS and SFSC participation on farm performance and survival, as well as understand price transmission and trade patterns. Consumer knowledge, confidence in, valuation and use of FQS labels and products will be assessed via cross-national survey, ethnographic and virtual supermarket-based research. Lessons from the research will be applied and verified in 6 pilot initiatives, focusing on less-developed and transition regions. These initiatives bring together academic and non-academic stakeholder partners in action research. The six pilot actions are: a school meals initiative to improve the nutritional outcomes and economic benefits for local agri-food producers; in-store trials (undertaken with a grocery retailer) to upscale sales of local produce; a scheme to stimulate a sustainable SFSC that adds value to the fishing community; and pilot actions to expand regional food labelling; increase sales of FQS products in non-traditional markers; and improve returns to local producers at food fairs and farmers’ markets (vi