RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Development and manufacture of new, more sustainable and safer materials using biobased functionalised additives based on lingin and tannins to improve fire resistance.' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

BIOSAFIRE goes back to nature to upgrade lignins and tannins, nature’s flame retardants, and unlock them for industrial application of biosbased flame retardants. Starting from already existing pilot plants, BIOSAFIRE upscales and broadens the available feedstocks to provide flame retardant in powder formats for five applications in four different sectors: naval, railway, home appliances and wood coatings.Featuring the same fire retardancy performance as chosen toxic benchmarks and enhancing safety and sustainability with an 80% of biobased content, BIOSAFIRE aspires to not only demonstrate its targets on 5 use cases, but also to create a material portfolio and a set of processing guidelines to enhance flame retardants substitution by the industry. This will open the possibility for biobased resins to exhibit good fire retardant properties. It will unlock a market opportunity worth USD 9.5 billion in 2028where Europe involves a 25% share and the sectors involved in the project 65% of the market share. BIOSAFIRE will design an industrial pilot plant to understand and overcome value chain barriers and create a robust techno economic assessment to promote the market uptake of the project results.BIOSAFIRE is an opportunity to test the EU JRC SSbD framework. The project will use a tiered approach to run the framework iteratively and provide a decision support toolset, link SSbD principles to early conceptual design and ultimately provide a software tool based on HEU SUNRISE methodology. The integration of SSH in the project will allow an enhanced social acceptance, further boosted by the training materials developed during the project.


**Keywords:** fire retardants, lignin extraction, tannin extraction and purification, safe and sustainable by design
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'MicroTher: Drug Discovery from the Microbiota' (MicroTher).

assistant: **Innovation**

The rapid increase in the prevalence of diseases caused by the disruption of the intestinal epithelium, also known as leaky gut syndrome, is a global cause for concern. Metabolic syndrome (MetSyn) and inflammatory bowel syndrome (IBS), two disease indications that occur as a result of a compromised intestinal mucosal membrane, collectively effect over 235 million people globally. In a healthy gut, the epithelial lining is tightly aligned to form a structurally robust barrier between the outside and the inside of the body. When this lining is compromised, immunogenic compounds such as bacterial endotoxins can infiltrate the body, causing systemic and local inflammation, resulting in diseases such as MetSyn and IBS. Through our ERC Advanced project FUNMETA, we have identified the ‘postbiotic’ molecule, indole-3-aldehyde (IAld), to be critical in the maintenance and restoration of intestinal epithelial integrity. Preliminary data already indicates the ability of IAld to repair damaged intestinal epithelium and to modulate symptoms of MetSyn and IBS in animal models. As these two indications are not only burdened by high prevalence rates, but also by ineffective or expensive treatments, there is strong potential in the clinical adoption of IAld. Therefore, the main aim of MicroTher is to further assess the clinical and commercial feasibility of IAld as a pharmaceutical agent.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Innovative Electrochemical Multiplex Biosensor for Detection and Quantification of Clinically Relevant Circulating miRNAs'.

assistant: **Concept**

Radical prostatectomy is currently the most used curative procedure in the treatment of localised prostate cancer (PCa). However, in 30-50% of interventioned patients Prostate Specific Antigen (PSA) increases on post-operatory, meaning that the cancer has spread. The rise in PSA is due to imprecision in preoperative staging, suggesting patients already had distant, undetectable disease. Another issue is that elevated serum PSA is not specific to malignant prostate disease, it cannot differentiate between indolent tumours or those that are/will become life threatening. Fatal cancer is most often due to metastatic disease but histopathological examination of biopsy or traditional imaging methods fail to detect the early disseminated circulating biological information highlighting the need for approaches that can detect biomarkers of cancer spreading at an early stage. Circulating amounts of non-coding microRNA (miRNA) have been shown to have a biological impact and to be clinically associated with cancer and are now seen as a new class of biomarkers that will allow earlier and more accurate diagnosis.The objective of INFORM is to develop an innovative electrochemical multiplex biosensor for detection and quantification of a panel of clinically relevant circulating miRNAs in intermediate-risk PCa patients that will be submitted to potentially curative surgery. By focusing on the development, optimisation and validation of a biosensor for miRNA profiling in PCa, discrimination of patients with local disease from those with more advanced PCa will be possible. The biosensor will rely on the selectivity of the sandwich assays and on the sensitivity of the photoelectrochemical detection to quantify, at the sub-fM level, circulating miRNAs that are associated with PCa. The quant
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Open Autonomous programmable cloud appS & smart EdgE Sensors' to be submitted under Horizon Europe.

assistant: **Abstract**

The massive increase in device connectivity and generated data has resulted in the proliferation of intelligent processing services to create insights and exploit data in a multi-modal manner. Currently, the most powerful data processing operates in a centralized manner at the cloud, which provides the ability to scale and allocate resources on demand and efficiently. Centralized processing and cloud hosting, bound and limit their services and applications to operate in a resource restricted manner, relying usually on large single entities to provide, i) Authentication, ii) Data storage, iii) Data processing, iv) Connectivity, v) Vendor-locked environments for development and orchestration. This significantly limits the user from its data governance and even identity management. Similarly, existing solutions for edge device authentication require a centralized entity to trust them and authenticate them, rendering a non-portable identification paradigm. OASEES aims to create an open, decentralized, intelligent, programmable edge framework for Swarm architectures and applications, leveraging the Decentralized Autonomous Organization (DAO) paradigm and integrating Human-in-the-Loop (HITL) processes for efficient decision making. The OASEES vision is to provide the open tools and secure environments for swarm programming and orchestration for numerous fields, in a completely decentralized manner. An important aspect in this process is identification and identity management, in which OASEES targets the implementation of a portable and privacy preserving ID federation system, for edge devices and services, with full compliance and compatibility to GAIA-X federation and IDSA trust directives and specifications. This situation solidifies the need for an integrated enabler frame
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Spatial variation in community structure: species, functional and phylogenetic diversity at different scales' under Seventh Framework.

assistant: **Concept**

Unifying community ecology and biogeography is essential for the advance of ecological research. Although spatial scale is known to be important to understand community structure, current knowledge on spatial variation of functional and phylogenetic diversity is limited. COMMSTRUCT aims to study how community structure and assembly vary in space across different extents and scales.Community structure can be described through different parameters, from species richness to composition in terms of traits (i.e. trait/functional diversity) or evolutionary units (i.e. phylogenetic diversity). Given that community assembly processes are affected by the functional characteristics of the coexisting species and their phylogenetic relatedness, the simple use of species richness as a measure of structure has important limitations. Thus, this project seeks the following specific objectives: (i) examine the factors affecting large-scale spatial covariation between species, functional and phylogenetic diversity; (ii) characterize cross-scale variations in the functional and phylogenetic structure of communities; (iii) identify environmental factors and other spatially-structured effects that may influence the cross-scale variations in the functional and phylogenetic structure of communities; and (iv) identify the main processes affecting community assembly at different scales. Spatial statistics, partial regressions and null models will be used to pursue these objectives, using data on the distribution of mammals and European dung beetles at different geographical extents and scales.The results of COMMSTRUCT are fundamental for the development of biodiversity science as they will contribute to build up the basis of the theory on how diversity is structured across spatial scales, ultim
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Easy-to-Implement Energy-Based Control Design for Systems of Conservation Laws' (EasyEBC), addressing dissemination and exploitation.

assistant: **Impact**

Secure, clean and efficient energy as well as resource efficiency are major societal challenges formulated in the EU Horizon 2020 Framework Programme. Many subsystems in energy, production and process industries are systems of conservation laws and their efficient operation relies on precise modelling and feasible control design. The port-Hamiltonian approach, developed in a vibrant European research community with the project supervisor as one of the leading figures, uses energy as the key argument for modelling and control of interconnected, nonlinear multi-physics systems, including systems of conservation laws.The aim of EasyEBC is to develop easy-to-handle energy-based control design procedures for nonlinear systems of conservation laws in the port-Hamiltonian framework. Linear and nonlinear methods from mathematical control theory of finite- and infinite-dimensional systems will be applied for analysis and control synthesis, e.g. semi-group theory, discretization techniques, and energy shaping. The mathematics will be masked behind a user-friendly frontend that offers transparent tuning criteria for the closed-loop dynamics. Bridging the gap between mathematical complexity and easy applicability of the design tools is the main challenge of the project.The capacity of the renowned supervisor, the application examples at the secondment partners, such as chemical and thermodynamic processes or energy-efficient building refrigeration, and the fellow’s experience in applying nonlinear energy-based control are essential for the scientific success of the project. As a long-term impact, EasyEBC will contribute to making nonlinear model-based control more accessible to engineers beyond academia.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Transcription Factor-mediated Induction of Cardiomoycyte proliferation.' in the context of a Horizon Europe call.

assistant: **Objectives**

Heart failure is a major global public health problem affecting over 23 million patients worldwide. There are no effective therapies for heart failure that regenerate the damaged heart muscle following injury such as a myocardial infarction. The adult mammalian heart has an extremely limited intrinsic capacity for regeneration due to the fact that mature cardiomyocytes are unable to proliferate. To date, attempts to re-induce proliferation in mature cardiomyocytes of the adult heart have not yet been translated into the human clinical context. Much remains to be learned about molecular mechanisms controlling cardiomyocyte proliferation in humans if the therapeutic potential for cardiac regeneration is to be realised. With my extensive training and expertise in molecular and stem cell biology I plan to generate and exploit an innovative live cell cycle reporter-based screening platform to identify Transcription Factors (TFs) that can be induce cardiomyocyte proliferation. The three major objectives of this research proposal are: 1. Develop a high-content screening system to monitor cardiomyocyte proliferation in 3D human cardiac organoids, which will then be used to:2. Identify (combinations of) TFs that drive the human cardiomyocyte cell cycle.3. Assess the therapeutic potential of TF activation for cardiac regeneration in a pre-clinical human cardiac model system. I will receive extensive training in the ex vivo cardiac tissue culture system (objective 3), which will complement my proven expertise in the generation of (genetically modified) 3D cardiac organoids and knowledge on cell cycle regulation (objective 1 & 2). Altogether, the tool development, results and training obtained during this project will put me in the forefront of the cardiac regenerative field.


**K
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Environmentally clean efficient, and easy to contact crystalline silicon solar cells (EC2 CONTACT)' to be submitted under Fifth Framework.

assistant: **Abstract**

The aim of EC2Contact (easy to contact) is to develop a metallisation process for crystalline silicon solar cells that is environmentally clean, highly efficient, and easy and robust processing. We will develop a metallisation process that is lead free, solvent free, and without silver waste. This topic is important to the end-user, partner P4, in applying for ISO14000, an international certified environmental care system. Metallisation is efficiency limiting due to high contact resistance and low conductivity. Our goal is to increase average efficiency by 10% relatively. The front side contact (3%), process yield (3%), and rear side contact (4%) will lead to this increase. Aluminium rear side reduces wafer strength and causes wafers to bend. Recently, scientists have shown that aluminium is necessary for high efficiency. Therefore, we will develop a new way of producing an aluminium rear contact. This will allow 30% thinner wafers to be used in production. We will increase process robustness further by widening the process windows by a factor of two. This will lead to a 3% average efficiency increase approximately. In total, EC2Contact will lead to a cost reduction of 40%.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Safety assUraNce fRamework for connected, automated mobIlity SystEms' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Safety assurance  of  Cooperative,  Connected,  and  Automated  Mobility  (CCAM)  technologies and systems is  a  crucial  factor  for their successful adoption in society, yet it remains to be a significant challenge. CCAM  must  prove  to  be safe and reliable  in  every  possible  driving  scenario.  It  is  already  acknowledged  that  for higher levels of automation the validation of these systems by real test-driving would be infeasible by conventional methods. Furthermore, certification initiatives worldwide struggle to define a harmonized approach to enable massive deployment of highly automated vehicles. Building  from  HEADSTART  and  other  initiatives, SUNRISE (Safety assUraNce fRamework for connected, automated mobIlity SystEms) will  develop  and  demonstrate  a  commonly accepted, extensible Safety Assurance Framework for the test and safety validation of a varied scope of CCAM systems. This will be achieved by: 1) Bringing the needs of heterogeneous CCAM use cases; 2) Defining a scenario-based database framework that will broaden the HEADSTART methodology; 3) Holistically addressing the CCAM test scenario generation;  4) preparing the required tools for comprehensive testing (virtual and physical), taking into account robustness, scalability, interoperability, quality and standardization; 5) integrating functional safety and cybersecurity; 6)involving the use cases from the initial stages, acting as a guiding principle within the project.The project will define, implement and demonstrate the building blocks of this Safety Assurance Framework: harmonized and scalable safety assessment methodologies, procedures and metrics taylored for use cases, a federated European Scenario Database framework and its necessary data interfaces, a commonly agreed simulatio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'High Performance Computing Governance Intelligence Gathering' under Horizon 2020.

assistant: **Concept**

The European Cloud Initiative implementation encompasses different elements and will require a solid governance setup. A cornerstone of this governance is a Joint Undertaking, planned to start activities in 2019. HPC-GIG proposes intelligence gathering services from the European HPC stakeholders to this future ‘HPC Governance’ - HPCG. It aims to facilitate a timely start of its operations, transparently and non-intrusively leveraging the HPC community know-how, organised with enough flexibility to align project activities with the programme schedule and needs during its ramp-up phase, and deliver timely and useful input to the HPCG.For this purpose the project will:-establish an effective and responsive communication channel with the HPC Governance;-engage all relevant stakeholders in the HPC and data ecosystem via dynamically managed ad hoc task forces;-develop knowledge registries and consolidate networks of expertise which may already exist;-link national and pan-European activities in the field, involving users, implementers and funders participating in the European HPC and Big Data activities;-organise workshops for stakeholder groups and/or participating in already-existing strategic HPC events;-create visibility and position the project within the European HPC and data ecosystem.The project partners are Europe’s reference players in the main areas of concern:(a) PRACE (Project Coordinator): provider of world-class HPC for scientific and industrial research; (b) ETP4HPC: industry-led think tank of European HPC technology stakeholders; (c) GEANT: the leading European collaboration providing advanced network, infrastructure and services for research and education. The project partners are very active stakeholders interested in reaching the ECI objectives. Moreover,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Validation of fully electrical controlled 14v/42v power components for internal combustion engine including the total thermal management' under Fifth Framework.

assistant: **Concept**

Aim of the proposal is the development a new auxiliary drives management system which eliminates the problems of the current system and enables an efficient and wide integration of electrical auxiliary drives in the new system generation. A completely new auxiliary drives management concept shall be developed covering following aspects: Integrated starter generator (ISG) Electrical, demand side controlled drives 14V/42V electrical board net New control strategies including start/stop, boosting, recuperative breaking etc.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Advanced digital european policy thinktank on innovation' (ADEPT) targeting Fifth Framework.

assistant: **Abstract**

The goal of the project is to provide European innovation policy makers and analysts with a convenient, digital means of communicating and tapping innovation policy related data and expertise. It will involve accessing and exploiting a comprehensive, up-to-date and reliable European and boarder International knowledge base within key information policy domains.