RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'The dynamical controls on the antarctic circumpolar current with the use of general circulation models - fram, occam, pop' (1994-1998).

assistant: **Innovation**

Research object and content It proposes to use numerical models and to determine the role of time dependant eddies in the antarctic circumpolar current by consideration of the vorticity budget. Training content (objective, benefit and expected impact ) It will use large scale ocean general circulation models for the diagnostic studies; advanced training in dynamical oceanography will be provided, and will provide a high quality environment for research in antarctic ocean modelling.The benefit will be advanced training in the fast developing area of ocean modelling wich will provide europeans with the expertise to lead the research field. Links with industry/industrial relevance(22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Pheromone Identification for Environmentally Responsible Control of Thrips' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Thrips are insects that are important crop pests in agriculture and horticulture. They cause most damage to protected (greenhouse) crops, which have an annual EU production of 37 billion euros. Growers are struggling to control thrips but are also under pressure to reduce pesticide use. The EU Directive on the Sustainable Use of Pesticides (2009) requires alternatives to pesticides to be used wherever possible. There is also the imminent threat that an invasive species, Thrips palmi, will devastate protected crops when it reaches the EU. This is a multi-disciplinary project that uses skills in biology and organic chemistry to improve crop protection in agriculture and horticulture by developing new methods for the monitoring and control of thrips. Aggregation pheromones of thrips can be used to monitor thrips populations so that pesticides are only applied when necessary and also to modify behaviour to enhance the effectiveness of control methods. The project will identify the aggregation pheromone of Thrips palmi and also make the aggregation pheromones of other pest thrips species easily available for monitoring and control. The project addresses the EU policy objectives of minimising the use of pesticides and promoting sustainable horticultural production methods that meet consumer requirements for a safe food supply chain and environmentally responsible growing systems. The success of the project depends on bringing together complementary skills. The MC fellow has significant skills in the organic chemistry of natural products, while the Keele group has considerable expertise in thrips biology, chemical ecology and the translation of research results into practical outcomes for horticulture. This research will develop an environmentally responsible method of monitor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Inflammation and de/remyelination coupling in EAE: A focus on the role of soluble TNF and receptors' under Sixth Framework.

assistant: **Concept**

Multiple sclerosis (MS) is a chronic debilitating disease of the central nervous system (CNS) that affects more than a million individuals worldwide. The disease develops through the immunologic attack and eventual destruction of the myelin sheath (demyeli nation) that protects neurons of the CNS. The body attempts to repair the ensuing damage through remyelination, which eventually succumbs to the destructive nature of the disease. Our goal is to employ Experimental Autoimmune Encephalomyelitis (EAE), the animal model of MS, to decipher the cellular and molecular events that influence disease processes. Tumour Necrosis Factor (TNF) is one of the immunological components that have proven instrumental for orchestrating the balance of de- and remyelination.We have developed conditional genetic animal models that differentially express soluble TNF (sTNF) vs. transmembrane TNF (tmTNF) and their receptors, p55TNFR vs. p75TNFR, to be exploited for the study of the evolution of EAE. We will specifically investigate how the cell-specific expression and signalling through TNF components affect cellular processes, including oligodendrocyte physiology and immune functions, as well as molecular events, such as signalling cascades, suspected or known to participate in the evolution of EAE. This study will extend our knowledge of the nature of EAE; it will reveal novel biological markers of disease progression and potential targets for its therapy.The project will benefit from the applicant's knowledge of autoimmune diseases a s well as her expertise in a variety of in vitro and in vivo imaging modalities, including confocal microscopy and optical imaging, which will be employed to address the proposed scientific questions. The applicant will be trained in using genetic animal models
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Solvation in ligand-receptor recognition' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

The aim of my research is to understand the solvation effect of hydrophobic biomolecules, and its role in molecular recognition and in drug design. Simulated unbinding and 'tethered-molecule' molecular dynamics simulations will be performed on a model system including different fatty acids bound to the adipocyte lipid-binding protein in the presence of water. In simulated unbinding, the model system will include the receptor, the ligand and water molecules, with the ligand bound to the receptor. Unbinding is observed using molecular dynamics to study the role of water in this process. The static and dynamic properties of water will be examined. In the 'tethered-molecule' approach, the ligand molecule is placed at different distances from the receptor, and the potential of mean force will be calculated to quantify the free energy changes. The results of these simulations will tell us how water mediates the ligand-receptor interaction.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Aerosol and Climate Response to NH3 in the NMMB/BSC Inter-Scale Model' (ACRoNNIM) under Horizon 2020.

assistant: **Objectives**

Atmospheric particulate matter reduces visibility, adversely affects human health and impacts Earth’s climate. Recent laboratory research has identified NH3 as a potentially important reactive species in the formation and aging of SOA, a significant but not-well-quantified class of aerosol particles. The goal of this proposal is to answer the questions: How does NH3 affect aerosol mass loadings and optical properties on a global scale? And, what impact do these effects have on air quality and climate? This will be accomplished by incorporating NH3-related SOA chemistry, currently being investigated by collaborators at the University of California, Irvine (UCI) into the state-of-the-art CACM/MPMPO SOA module. The updated module will be deployed in the NMMB/BSC global chemical weather model, maintained at the Barcelona Supercomputing Center (BSC). Model predictions will be validated by field measurements collected during an IDAEA-CSIC campaign that the experienced researcher (ER) will participate in, as part of this proposal. This will result in one of the most advanced SOA treatments available in global models, and allow an investigation of the impact of NH3 on global SOA, air quality and climate, thus directly impacting a crosscutting issue of the Horizon 2020 Program, climate action. The ER has experience using laboratory results to develop mechanisms for aerosol processes, and in the development of CACM/MPMPO as a graduate and postdoctoral researcher at UCI. This experience, coupled with training in global model development at BSC, will provide ideal conditions to successfully execute this proposal, and strengthen the collaboration between the European BSC and IDAEA-CSIC, and US-based UCI teams. By the end of the Fellowship, the ER will have hands-on experience in fie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Wigner phase in quantum dots' (WIPQD).

assistant: **Concept**

A theoretical study of the quantum Wigner phase of electrons confined in semiconductor quantum dots (and related confined systems, e.g. rings and wires) will be performed.The objectives of the project are:- Determination of the mechanism for breakdown of the maximum density droplet and for the formation of the Wigner phase in quantum dots, quantum rings and wires. The aim is to solve the controversy between the proposed edge reconstruction and an intermediate stage of crystallization where a hole in the centre of the electron charge density appears;- Study of the Wigner phase in systems with broken symmetry (and with anharmonic confinement). In this case the rotational invariance is broken and most of the available approaches fail to describe such systems;- Study of the Wigner phase in large quantum dots with disorder induced by the local fluctuations of the confinement potential.Phase diagrams for the quantum dot ground state will be constructed as function of the relevant parameters, e.g. magnetic field, confinement strength, anharmonicity and disorder. The theoretical results obtained during the realization of the project will be compared with the experimental data of transport and capacitance spectroscopy [e.g. Oosterkamp et al., Phys. Rev. Lett 82, 2931 (1999), Zhitenev et al, Phys. Rev. Lett. 79, 2308 (1997).The project will be realized using the unrestricted Hartree-Fock method and a novel configuration interaction scheme with a multi-centre basis. This novel method of solution of the Schroedinger equation yields exact results in the high- magnetic field limit, in which the quantum system reproduces the classical configurations.Furthermore, this approach is well suited to tackle systems with broken symmetry and disorder. The Antwerp research group is an internati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'EU routes for High pEnentration of solaR PV into lOcal nEtworkS', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The overall aim of the project is to enable the continued development of community-owned PV by developing viable business models that address the concerns of network operators. The project will work with communities and network operators to develop approaches that will enable subsidy-free solar PV projects that have a neutral or positive impact on network management.  The project will: 1. Identify and develop social enterprise models that enable increased deployment of solar PV in grid-constrained areas.2. Carry out cost-benefit analysis and economic feasibility assessment and develop business models that enable community groups to store, utilise, aggregate and trade solar electricity within localities as well as simply exporting excess energy to the grid.3. Empower citizens to have greater ownership over their energy supply, through removing key barriers to community PV, democratising energy and recycling profits from energy generation into host communities.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Robust and Efficient Approaches to Evaluating Side Channel and Fault Attack Resilience'.

assistant: **Concept**

Implementing cryptography on embedded devices is an ongoing challenge: every year new implementation flaws are discovered and new attack paths are being used by real life adversaries. Whilst cryptography can guarantee many security properties, it crucially depends on the ability to keep the used keys secret even in face of determined adversaries. Over the last two decades a new type of adversary has emerged, able to obtain, from the cryptographic implementation, side channel leakage such as recording of response times, power or EM signals, etc. To account for such adversaries, sophisticated security certification and evaluation methods (Common Criteria, EMVCo, FIPS…) have been established to give users assurance that security claims have withstood independent evaluation and testing. Recently the reliability of these evaluations has come into the spotlight: the Taiwanese citizen card proved to be insecure, and Snowden’s revelations about NSA's tampering with FIPS standards eroded public confidence.REASSURE will (1) improve the efficiency and quality of all aspects of certification using a novel, structured detect-map-exploit approach that will also improve the comparability of independently conducted evaluations, (2) cater for emerging areas such as the IoT by automating leakage assessment practices in order to allow resistance assessment without immediate access to a testing lab, (3) deliver tools to stakeholders, such as reference data sets and an open-source leakage simulator based on instruction-level profiles for a processor relevant for the IoT, (4) improve existing standards by actively pushing the novel results to standardization bodies.REASSURE's consortium is ideal to tackle such ambitious tasks. It features two major circuits manufacturers (NXP, IDEMIA), a hig
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Reinforcing IPT capacities in Genomic Medicine, Non Communicable Diseases Investigation and international cooperation' in the context of a Seventh Framework call.

assistant: **Objectives**

The aim of the proposal is reinforcing IPT capacities (i) in genomic medicine, withapplications in Non Communicable Diseases (NCD) investigation, and (ii) in International Cooperation activities. This project will facilitate joint research and innovation related activities between European and Tunisian researchers in the field of NCD.To achieve these aims the following actions are proposed: Setting and implementing trainingmodules, two trainings on international project setting in the frame of European FrameworkProgram, four advanced courses and theoretical and practical workshops in various aspects ofstructural and functional genomics, with a particular emphasis on NCD investigation will beorganized. Exchange of visits between IPT, IP Paris and other EU laboratories working on relevantfield are also planned to improve networking capacities. Two pilot projects will be performed. The aim of the pilot projects is to learn how to design and implement genetic diversity and health projects in post genomics. The pilot projects will also help stimulate EU-Tunisia cooperation, and develop competencies in genomic medicine.GM‐NCDin‐Co targets Institut Pasteur de Tunis, an independent governmental institution, under the tutorship of the Tunisian Ministry of Health. This more than centenary institution is considered as a national and regional centre of excellence in particular in the field of infectious diseases. To answer to the new challenges of the epidemiological transition and with the increase of prevalence of NCDs,IPT has developed new activities related to the investigation of the genetic basis of monogenic andmultifactorial diseases. Reinforcing these promising activities has a great potential to benefit EUresearch institutions through new international cooperation activit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Beyond the blood: Diversity and Mortality Impact of Haemosporidian Parasites in European Birds.' (MorPreDiv) targeting Horizon Europe.

assistant: **Abstract**

Haemosporidians (protists) are widespread vector borne parasites that infect different vertebrate hosts, including humans and birds. Avian haemosporidians are globally distributed and classified in three main genera, Plasmodium, Haemoproteus and Leucocytozoon. They are of One Health, veterinary and economic importance, with spillovers between wildlife and livestock or non-native birds in zoos or aviaries. Their prevalence and diversity are usually estimated through the presence of gametocytes (erythrocytic stages) in blood smears and their molecular investigations (barcoding region in the mitochondrial cytochrome b gene), mainly in bird species that are caught by mist nests. However, this does not reflect the true prevalence and effect of these parasites, as many bird species are under-sampled and tissue stages, which can and do cause mortality, are under-studied. This project will understand the scale of mortality associated with infection status and spillover dynamics of haemosporidian parasites in European passerine and non-passerine birds. First, I will investigate a wide spectrum of bird species for the presence and diversity of the parasites and test mechanism of co-evolution with their hosts, using collected blood samples and tissue samples obtained from collaborators. Second, I will use the carcasses of common bird species dead from natural causes and collected by our collaborators to investigate the tissue stage development of the parasites, their prevalence, and effects on birds. These will result in a step change in our understanding of the epidemiological and pathological implications of avian haemosporidian infections, through the newly uncovered host-parasite interactions, and help conservation and management of bird populations.


**Keywords:** Prevalence
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Integrated Biosensor System for Label-Free In-Vitro DNA and Protein Diagnostics in Health-Care Applications' (BIOGNOSIS) under Sixth Framework.

assistant: **Objectives**

The main objective of this project is to develop a uniquely integrated DNA and protein detection system for medical diagnostics. Due to its ease of use and cost-effective nature, the system allows for fast as well as reliable DNA and protein testing. Aiming for point of care and doctor's office applications, e.g. early cancer recognition, this new testing system will improve public health. Moreover the project will enable a broad range of future applications in genomic risk analysis, individualized therapy and antibody detection for identification of diseases, resistances and allergies. Today bio-molecular detection is a promising technology for medical diagnosis with a high socio-economic impact.However, due to its complexity and costs, today's systems are restricted for use at specialized laboratories, making testing expensive and time-consuming. This projects aims to overcome these problems by providing a detection system based on direct electrical read-out, which can improve robustness and substantially decrease costs. This multi-analyte detection system includes novel integrated sensor disposables consisting of sensor arrays, on-chip CMOS read-out circuit, the biochemical sensor interfaces as well as suitable assays. By detection of mass changes at their surface, sensors work label-free according to key-lock principles.Recent progress in DNA and protein cancer marker testing will form the basis for the development of assays for the new system. An easy-to-use read-out setup will be developed, meeting requirements of robustness and usability. A clinical validation of the system in early diagnosis of breast cancer will demonstrate the enormous impact of this key technology for public health.The project will facilitate the entry of sensor array systems into the enormou