RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Redefining the future of cultural heritage, through a disruptive model of sustainability' (ReInHerit), addressing dissemination and exploitation.

assistant: **Impact**

ReInHerit aspires to disrupt the current status quo of communication, collaboration and innovation exchange between museums and cultural heritage sites, in a sense that it will connect cultural heritage collections and sites, and present Europe’s tangible and intangible heritage to citizens and tourists in their wider historical and geographical contexts. The ReInHerit project is proposing a very innovative model of sustainable heritage management, through which a dynamic network will be born; this network comprised of cultural heritage professionals, innovation and cultural heritage solution tech experts, researchers, national museums, regional and local museums, and representative managers of Heritage Label sites. ReInHerit is also supported externally, by relevant municipalities, regional and local museums, which will also enhance the communication and cooperation of the cultural heritage sector across the EU and beyond. The ReInHerit proposed model will be based on the development of a digital cultural heritage ecosystem, where all the key stakeholders (museums, heritage sites, policy makers, professionals and communities) will have an open and collaborative space to experiment, share and innovate. This will be achieved through the creation of an innovative Digital Hub. Tools and resources (on training, tourism, conservation, preservation, knowledge creation, content use/reuse, illicit trafficking of goods) necessary for sustainable management will be shared through the digital platform that will host the ecosystem. This ecosystem will also be the experiential open-ended space that will support and generate entrepreneurial initiatives, knowledge produced through co-creation, curation of digital content and visitor experiences.The proposed work plan includes a variet
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Long non-coding RNAs that regulate glial cell function in the diseased heart'.

assistant: **Concept**

Despite progress in acute treatment, heart disease remains the leading cause of death worldwide. Current treatments fail to prevent cellular disease processes or to promote tissue recovery after cardiac events. Since cardiac disease is accompanied by dramatic changes in neuronal integrity, understanding of the factors that regulate cardiac neuronal function and remodelling could facilitate development of novel therapies for heart disease.Long non-coding RNAs (lncRNAs) represent attractive therapeutic targets due to their highly cell type specific expression and function. Several lncRNAs were indeed shown to be causally involved in heart disease, but the vast majority of cardiac lncRNAs still await characterization.The heart is densely innervated by nerve fibres which regulate cardiac function on a beat-to-beat basis. In turn, glial cells (GCs), which cover almost all neuronal cell surfaces, locally regulate neuronal function and remodelling. While neuronal function and remodelling play a key role in heart disease, little is known about the role of cardiac GCs and their lncRNAs.My preliminary data suggest that cardiac GCs express many cell type specific lncRNAs that are deregulated in diseased conditions. To identify cardiac GC lncRNAs with therapeutic potential, I will 1) characterize cardiac GC populations that mediate neuronal remodelling in the heart, 2) identify conserved lncRNAs that determine cardiac GC identity and function, and 3) characterize their interaction partners and their ability to regulate key GC functions.These objectives will be addressed using cutting-edge techniques, including single cell sequencing and multiplexed CRISPR interference, during a fellowship at the research group of Prof. Engelhardt in Munich. To do so, I will receive extensive interd
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Early clinical development of a live, attenuated combination vaccine against Shigella and ETEC diarrhoea'.

assistant: **Concept**

Although vaccination is an effective way to reduce the huge disease burden associated with diarrhoea caused by enteric pathogens, many attempts to develop vaccines for shigellosis and ETEC infections have failed and a number of current approaches are too complex and costly to provide an adequate solution for LMICs.  This Consortium is dedicated to advancing a radically new approach against Shigella and ETEC based not on the immunodominant, but highly variable Shigella LPS O-antigen, target of almost all past and current vaccine development efforts. There are four pillars on which the ShigETEC vaccine has been designed: (i) Elimination of the LPS O-antigen to allow recognition of multiple antigens on the cell surface that are shared among different serotypes of Shigella and are increasingly being recognized as important in protection from shigellosis. These antigens are also closely related to those of ETEC and may also help in protecting against that pathogen as well. (ii) Elimination of the invasiveness of Shigella by disruption of the invasion complex resulting in a much safer/less reactogenic oral vaccine that can take advantage of gut mucosal immunity, possibly allowing administration of high vaccine doses and therefore addresses the low immunogenicity seen with other live attenuated vaccine candidates. (iii) Addition of detoxified toxin antigens of ETEC that will induce neutralizing/blocking antibodies to these critical virulence factors. (iv) Rational molecular design of ShigETEC will allow future generations of vaccines to include additional antigens for other pathogens.  The work programme entails manufacture of clinical trial material, first-in-human testing for safety and immunogenicity in non-endemic adults, a sero-epidemiology study to learn about natural im
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Evolutionary toxicology by anthropogenic pollution in invasive crayfish populations' in the context of a Horizon 2020 call.

assistant: **Objectives**

Climate change and biodiversity loss are one of the biggest threats facing the world in the next decade. Invasive alien species (IAS) are one of the most important direct drivers of biodiversity loss. While evolutionary processes and rapid adaptation have recently been linked with the increase of invasive capacity of IAS, still there is little known about the mechanisms involved in their success. EvoTox is an interdisciplinary project that seeks to address how IAS populations can evolve and adapt rapidly in response to environmental stressors. EvoTox focuses more particularly on the study of the mechanisms that facilitate the rapid adaptation of the crayfish Procambarus clarkii in aquatic areas with high-level of anthropogenic pollutants. The study involves both field and laboratory approaches using technics from several scientific fields such as evolutionary biology, toxicology, physiology, ethology and molecular biology. The studied populations come from three sampling stations, with freshwater and brackish water bodies, around the French Mediterranean coastline and adjacent aquatic areas, where P. clarkii has successfully established and environmental characteristics such as salinity and chemical pollutant concentrations differ. Understanding the mechanisms that contributes to the rapid and adaptive evolution in P. clarkii is important for identifying candidate genes involved in invasiveness, and, more generally, predicting future invasion scenarios, improving management and risk assessment of IAS in Europe and worldwide. EvoTox also contributes to the European Green Deal and the EU Biodiversity Strategy for 2030 by addressing IAS issues and their ecological and economic repercussions. EvoTox includes the training and the two-way transfer of knowledge between the res
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'DAYUSE: the European game changer that creates a disruptive value-adding exploitation model for Hotels.' (DAYUSE), addressing dissemination and exploitation.

assistant: **Impact**

Created in late 2010, dayuse.com is the innovative world leader in online reservation for the emerging ""day use"" hotel room segment in a typical ""Blue Ocean"" strategy.It provides an answer to this key question ""Why should I book a hotel room for a full overnight price when I only need it for a few hours?""The Company now relies on a network of over 4,500 partner hotels. The service is provided on a day-time allotment pricing basis. DAYUSE  boasts over 300,000 bookings p.a. which represents now one reservation per minute!With the recent signature of agreements with major hotel chains such as AccorHotels, Hilton, Marriott that want to open their huge hotel networks to dayuse.com, a large-scale industrialization phase looks urgent.DAYUSE has now the ambition to leverage on its leader position in the ""day use"" segment to shake completely the Hospitality Industry by imposing gradually and globally a new scalable industry standard based on an hourly service/rate, 24 hours a day, similarly to industries like car renting.Concretely, the company targets to provide to hotels a DAYUSE Proprietary Management System (PMS) called DMS delivered through SaaS with a ground-breaking pricing ""per transaction"" mode.The PMS market is estimated at $1.5 billion in 2016 and expected to grow to $2.0 billion in 2024.DAYUSE targets its gradual smooth adoption, first as a complementary tool to existing PMS and finally as a full substitute. DAYUSE will then extend its reach to the whole Hospitality Industry while integrating other distributors. The company wants to be the European game changer in an industry where North American players prevail.This SME Instrument Phase 2 project represents for DAYUSE the very last step to the market. For 24 months, it will prepare and fine-tune the IT too
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Networking and market approach to tackle the bottleneck of deploying micro and nanofluidics in Europe'.

assistant: **Concept**

Micro & nanofluidics is characterized by a broad number of research groups and enterprises developing knowledge and technology for many diverse application fields. The creation of a European network with the main research groups working on these lines will allow researchers to analyze better the main challenges for micro & nanofluidics applications (system integration, manufacturability and affordability) in order to tackle the bottleneck of its deploying in EuropeIn the network, researchers share knowledge to identify ways to overcome the technological limitations through different actions: workshops, meetings, groups of experts and white papers. The network will start with partner centers, but the idea is to identify the European stakeholders and engage them in the network, to increase the ability to address the technology challenges. In addition, a proactive approach with EEUU & Asia will be carried out, as well as an analysis of complementarity between several KETs.In other hand, to foster innovation in products and/or processes and ensure the success of implantation in the market a clear market focus is mandatory throughout the project, identifying the needs of different industrial sectors.  So, It will be essential to involve industry in activities carried out in the network through industry associations and technology platforms. Industry involvement will materialize in several actions: - Joint working groups (industrial needs, value chain, technical challenges, standardization)- Sectorial workshops where research centers present their capacities and industries their needs in order to match them and generate ideas of projects- Design a pilot project emerged from the project ideas of the sectorial workshops Finally, to facilitate and speed up the industrial exploit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Agrobiological products for crop production improvement: a novel approach towards a sustainable agriculture' (BIOAGRIBOOSTER) targeting Horizon 2020.

assistant: **Abstract**

Iden Biotechnology S.L. is a private company founded in 2006 with the mission to serve the needs of the agri-food industry. We focus our activity in the development and commercialization of high-quality technology, working from an agrobiotechnological approach.  The success of our business model relies on a deep understanding of the agri-food sector needs, thanks to a close collaboration with the industry.Over the past years we have been engaged in the development of innovative products and technologies for plant productivity enhancement. In the context of these projects, we came up with a disruptive technology for the production of a new agrobiological product, particularly a biostimulant, which was found to increase crop production by 20-25%, while at the same time enabling a reduction of the use of agrochemicals by 65%.Unlike the competing biostimulant products, BIOBOOSTER proposes a completely different approach, which will not entail any effect in soil because in fact our biostimulant is not based on any substance aimed at modifying the soil structure. The overall concept of the BIOBOOSTER project is based on the discovery that the volatile elements emitted by fungal fermentation, stimulate plant growth without the need of any physical contact of these fungi with the plant or the soil. As the effect is produced by these volatile elements, which do not remain in contact with the plant/soil, there is no possible way for soil structure modification in the long term. The innovation of the BIOBOOSTER project relies on two main concepts: a) the production process and b) the biostimulant product. The both innovations have been protected by an international patent application (PCT/ES2011/000125) and now we seek performing the necessary steps towards production scaling up a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'FLEXOLIGHTING'.

assistant: **Concept**

The flexolighting programme is focussed on research and innovations on materials, processes and device technology for OLED lighting with the intention of building a supply chain within Europe. The aim is to realise OLED devices over a large area/surface with high brightness, high uniformity and long life time. A demonstrator will be built and delivered at the end of the project. The main targets are (i). Cost of the lighting panels should be less than Euro 1 per 100 lumens. (II). high luminous efficiency, in excess of 100 lm/W with improved out-coupling efficiency. (ii). white light life-time of at least 1000 hours at 97% of the original luminance of 5000 cdm-2.(iii). The materials and the devices therefrom will allow for differential aging of the colours, thus maintaining the same colour co-ordinates and CRI over its use. (iv). Attention will be paid to recyclability and environmental impact of the materials and the OLED lighting systems. Flexolighting project will also ensure European industrial leadership in lighting.The introduction of OLED Lighting technology is held back by the current cost of the systems, life-time and poor uniformity of luminance on large area panels. The programme aims to combine existing state of the art OLED materials technology (Thermally activated fluorescent materials (TADF) and phosphorescent emitters and world class transport materials) with new developments in processing technologies (Organic Vapour Phase Deposition (OVPD) and  printing technologies) to develop new next of generation low cost OLED lighting systems to move forward to scale up and full scale production on novel planarized flexible steel substrates with cost effective conformal encapsulation method. The transparent top contacts made of thin metallic films, conducting polym
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Co-operation for the Convention on Biological Diversity' (CO-OP4CBD), addressing dissemination and exploitation.

assistant: **Impact**

CO-OP4CBD aims to enhance coordination of the EU support to advance the implementation of the CBD, and doing so make more effective use of existing expertise and initiatives. This will lead to greater coherence in the ways in which the EU, its Member States and associated countries identify and draw on available expertise, improved advice and support to a range of CBD processes, and a more coordinated and cooperative approach in the engagement of experts in supporting implementation of other intergovernmental agreements and processes. Therefore the core focus of CO-OP4CBD is to support the increase facilitation of technical and scientific cooperation in European countries and elsewhere. This will be achieved through the implementation of a set of Coordination and Support Actions: 1) building on existing networks of experts and institutions; 2) engaging experts into the CBD processes; 3) supporting the implementation of monitoring, reporting and review; and 4) increasing technical and scientific cooperation. These actions are targeted at and will benefit the EU, its Member States and associated countries. Many actions and outputs of CO-OP4CBD however will be of interest and use to other Parties to the CBD.


**Keywords:** CBD, technical and scientific cooperation, clearing house mechanisms, synergies, capacity-building, implementation, monitoring, review, post-2020 global biodiversity framework
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Mechanics of the cytoskeleton: active polymer networks' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

The cytoskeleton is a complex and highly dynamic network of protein filaments, motors, regulatory agents - such as cross-linkers or bundlers - and membranes, that gives eukaryotic cells their shape and mechanical strength and drives dynamic cell functions such as cell locomotion, division, and growth.I will explore how the microscopic structure and the active and passive dynamics of the cytoskeleton determine cellular mechanics. I aim towards a quantitative physical understanding of the molecular mechanisms of dynamic cell functions. This requires a dual approach, integrating in vitro studies of active cytoskeletal protein networks with in vivo investigations of cells.The influences of cross-linking and motor proteins on the microstructure and micromechanics of cytoskeletal networks will be studied using networks of reconstituted actin filaments. I will compare bundled and isotropically cross-linked actin networks, and study the non-equilibrium properties created by the activity of tension-generating motor proteins.Since the cytoskeleton is intrinsically heterogeneous it will be essential to use and develop microrheological techniques that can resolve local variations of mechanical properties on a micrometer scale. Colloidal probe particles will be inserted into in vitro networks and living cells (endothelial cells, fibroblasts, osteocytes, and neurons), and their thermal motion will be monitored with light microscopy, laser interferometry, and diffusing wave spectroscopy.I will use active manipulation of the probe particles with optical tweezers to examine the non-linear regime of the viscoelastic response. The project is highly interdisciplinary, since it integrates cell biology and biochemistry with soft condensed matter and polymer physics, statistical mechanics, an