RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'From paradise to mass extinction: correlating and comparing low and high latitude basins during the greatest Permian extinction events and subsequent faunal recoveries.', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Drastic global climate change during the Permian resulted in two of the greatest mass extinction events of all time, one around 260 Ma ago and the other around 252 Ma ago. Arguably the best record of these events on land is preserved in the main Karoo Basin (MKB) of South Africa, which was situated in higher latitudes (~60° S) at those times. Because of the relatively poorer fossil record from lower (0-15°) palaeolatitudes, latitudinal differences in faunal assemblages, and lack of precise radiometric dates, global applicability of extinction and faunal recovery patterns observed in the MKB has long remained elusive; we simply lacked the necessary data. As such, stratigraphic correlations between basins are tenuous. Moreover, it is not known whether the terrestrial expression of the two greatest mass extinction events of the Permian, and subsequent ecosystem recovery, are preserved in western Europe. ExtinctRecov is a novel interdisciplinary project that aims to, for the first time, combine palaeontological, sedimentological, stratigraphical and geochronological data to correlate the Permian-Triassic Spanish and French basins and the MKB. ExtinctRecov will also explore patterns of faunal turnover, extinction, and recovery during the mid-to-late Permian and across the Permo-Triassic boundary i.e. between 265 and 250 Ma ago. The proposed project draws on the geological, geochronological, and palaeontological advances and work undertaken during the past two decades in the Pyrenees and Lodéve basins (Spain and France) and the main Karoo Basin (South Africa), which finally makes this ambitious project possible. Implications of the results from the proposed project include new and key insights on the faunal communities present in this part of Pangea and a better understanding
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Mendelian cytogenetics network: systematic identification of disease genes by structural chromosome re-arrangements'.

assistant: **Objectives**

To systematize and optimize the detection and mapping of disease-associated balanced chromosome re-arrangements (DBCRs) detected by routine cytogenetic laboratories in order to facilitate the identification of novel phenotype/genotype associations.The task of linking clinical features (phenotype) with mutations (genotype) within the thousands of new genes that will be identified within the coming years, will be formidable. One of the most important key factors behind the successful positional cloning of many disease genes have been disease-associated balanced chromosome re-arrangements (DBCRs) that truncate/inactivate the relevant genes. Although such DBCRs are generally considered to be very rare, they are regularly encountered in diagnostic cytogenetic laboratories. However, most of these cases are never reported since they do not constitute recognisable, known disease entities, and since the individual breakpoints involved rarely can be linked to known mapped disorders. The estimate is, that more than half of these disorders are caused by one or more of the breakpoint(s) involved, by interference with specific genes. Since these associations cannot be defined at the level of individual laboratories, the project will systematise the identification, mapping and cloning of novel DBCRs: 1) by establishing a large network of European cytogenetic laboratories, 2) by establishing a central secretariat and database that will facilitate the collection, comparison, and dissemination of data and material from DBCRs within this network, 3) by the generation and distribution of standardised molecular probes for breakpoint mapping, 4) by the dissemination of technical know-how by targeted training within the network, and 5) by the provision of the necessary technical know-how and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'OPTImised WInd Supported vEssels' in the context of a Horizon Europe call.

assistant: **Objectives**

The need to reduce energy consumption and emissions to bring global warming to a halt is unprecedented. Although there are energy saving strategies, most innovations cannot simply be merged in conventional ship design. As the solution for making ships carbon neutral will likely come from the use of several energy sources, a clever energy management becomes a key element in a unified ship system. De-rating of engines combined with sailing at slower speed seems to be a relatively easy way to reduce fuel consumption and GHG emissions and will most likely be used in the industry. However, this does come with reduced transport work per ship and reduced earnings. In our view, most other savings methods can deliver savings up to about 15%, not the substantial savings that are required. OPTIWISE aims at two solutions that when combined go well beyond 30% when the innovations are delivered as proposed in this project: Wind propulsion with a rigorous, holistic optimised ship design, control and operation, including a change in conventional propeller propulsion. Wind propulsion is showing its potential in research and market introductions. The holistic ship design and operation pair well with that. For common ships there is much to be gained, especially with the increased freedom in the aft ship geometry with a shift to electric propulsion. Making best use of wind propulsion also requires a rethink of designs, control and operations. To meet the objectives of this call, generic tool and methodology development are planned for optimization, performance and energy management. New developments will be applied to 3 Demo cases, consisting of a Bulk Carrier, a Tanker and a Passenger Vessel. Verification of the results will be done by testing a rotor sail rig, model tests on two ships an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Feedback Levitation on an Inverted Potential: A new tool for macroscopic quantum physics, sensing and information thermodynamics' in the context of a Horizon Europe call.

assistant: **Objectives**

The control of levitated mesoscopic objects has developed into a flourishing field promising significant advances in sensing technologies,  stochastic and quantum thermodynamics as well as macroscopic quantum physics. While optical levitation has already reached operation in the quantum regime, internal heating by absorption is a major challenge.With FLIP (Feedback Levitation on an Inverted Potential) we propose an original solution: dark field optical detection plus active feedback control provides position stabilization (without additional confining potential) and cooling to a close-to-pure quantum state without absorption. FLIP goes beyond the state of the art in several ways. It provides access to quantum control of absorbing objects in high vacuum (e.g. spin mechanics with NV-centers). It opens the door to large quantum superpositions via free-fall experiments with internally cold particles. It enables sensing and information thermodynamics with unstable potentials in the quantum regime.Following the recent demonstration of quantum limited position readout, real-time state reconstruction and feedback cooling to the ground state, it is the ideal time to develop levitation in the dark optical field. A controllable inverted potential for levitated particles is available in the host group, such that the project can be implemented from day zero and expanded towards a 3D dark quantum trap. Close collaboration with the Aspelmeyer group (partner group) and Prof. Kugi (ACIN) who jointly achieved feedback based ground state cooling will facilitate the implementation of FLIP.My expertise in FPGA-based optical feedback control puts me in a perfect position to implement FLIP. At the host group, I will expand my background in optomechanics, and quantum optics. Finally, continuin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'An innovative approach for renewable energy storage by a combination of hydrogen carriers and heat storage' in the context of a Horizon 2020 call.

assistant: **Objectives**

The main objective of the HyCARE project is the development of a prototype hydrogen storage tank with use of a solid-state hydrogen carrier on large scale. The tank will be based on an innovative concept, joining hydrogen and heat storage, in order to improve energy efficiency of the whole system. The developed tank will be installed in the site of ENGIE LAB CRIGEN, which is a research and operational expertise center dedicated to gas, new energy sources and emerging technologies. The center and its 350 staff are located at Plaine Saint-Denis and Alfortville in the Paris Region (F). In particular, the solid-state hydrogen tank will be installed in a Living Lab aimed to develop and explore innovative energy storage solutions. The developed tank will be joined with a PEM electrolyzer as hydrogen provider and a PEM fuel cell as hydrogen user.The following goals are planned in HyCARE:- High quantity of stored hydrogen >= 50 kg- Low pressure < 50 bar and low temperature < 100°C- Low foot print, comparable to liquid hydrogen storage- Innovative design- Hydrogen storage coupled with thermal energy storage- Improved energy efficiency- Integration with an electrolyser (EL) and a fuel cell (FC)- Demonstration in real application- Improved safety- Techno-economical evaluation of the innovative solution- Analysis of the environmental impact via Life Cycle Analysis (LCA)- Exploitation of possible industrial applications- Dissemination of results at various levels- Engagement of local people and institution in the demonstration site


**Keywords:** Metal hydride, hydorgen storage coupled with thermal energy storage, integration with electrolyzer and fuel cells
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'World’s first complete motion-preservation 'Implant-less' surgical correction for Scoliosis' (ImplantFreeSpine) under Horizon 2020.

assistant: **Objectives**

Scoliosis affects 2-3% of the world population i.e. about 12 million people in the EU. 20,000 cases of severe scoliosis are reported each year in the EU but less than 3,000 cases ever undergo surgery due to cost and complexity of the surgery. Severe cases of scoliosis are treated by spinal fusion; a major surgical procedure that makes the spine permanently rigid restricting physical activities and permanent arrest of spinal growth. The impact of spinal deformity caused by scoliosis on the quality of life before and after surgery is huge compared with other chronic conditions such as arthritis, chronic obstructive lung disease, diabetes and hypertension.Due to the need for an alternative method for better correction of scoliosis deformities we have developed novel devices and a highly innovative care model involving a safer and significantly less invasive, complete cure which preserves spinal mobility and growth potential. Our solution will result in reduced cost of treatment by over 40% because of shorter hospitalisation, reduced operating time, elimination of additional procedures and lifetime care costs.Spine surgery currently holds a €10.2 billion global market share and is estimated to grow at a compound annual growth rate of 6.9% to reach €17.5 billion by 2022. We aim to capture a market share of 0.1% in 5 years post commercialisation of our project and earn compound revenues of €42.5 million by selling our devices over the same period.In Phase 1 of this project we intend to conduct detailed planning of the testing and design optimisation phases, carry out a market study plan, identify and engage international partners and develop a draft business plan for use upon commercialisation within a period of 6 months.In Phase 2 we will develop an advanced prototype meetin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Polymers for polymer-dispersed liquid crystal displays'.

assistant: **Innovation**

Polymer-dispersed liquid crystal films are thin films composed of microdomains of a liquid crystalline material in a polymeric matrix. A display cell is formed by placing such a film between glass plates, coated with transparent electrodes. In the 'off' state the cell is highly opaque due to strong scattering by the LC domains. By switching on an electric field across the cell it becomes transparent. Contrary to conventional TN displays PDLC's don't need polarisers. Switching is based on changes in scattering rather than absorption. This makes PDLC a favoured display principle where high brightness is required. One way of making these displays is polymerisation-induced phase separation in a solution of monomer in LC. Photopolymerisation is the preferred method of inducing the reaction since it allows independent choice of temperature. A problem still to be solved is the proper control and minimisation of hysteresis. It is proposed to investigate the origin of hysteresis using simple model systems, the morphology of which can be well controlled.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Improvising Europe: Jazz, Cultural Globalisation and the Reinvention of Multiethnic Identities' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The research project focuses on issues of musical socialisation, cultural assimilation, financial strategies and gender inequalities within the jazz scenes of three major European cities: Barcelona, Budapest and Manchester. These three cities are illustrative of fundamental changes in the way that contemporary music scenes in Europe are responding to challenges of globalisation and cultural assimilation. This is most apparent in the many hybrid musical forms being developed by Europe’s traditional (Gypsies) and current (immigrant diasporas) ‘quintessential others’ to express cultural identities. Given that each selected scene’s functioning is closely linked to peculiar ethnic and racial characteristics, the three scenes provide compelling examples of the way in which jazz-related cultural practices reflect, shape and reinvent Europe’s cultural landscape. This interdisciplinary research project of transnational comparative scope is expected to generate new knowledge on the contemporary musical expressions of cultural diversity and assimilation strategies through music in Europe, which is essential to design projects that enhance intercultural dialogue. The following questions will guide the project: How do musicians construct the trajectory of their musical (dis)tastes and how it relates to their socioeconomic status? How does improvised music function to achieve cultural assimilation and (at the same time) to maintain distinctions linked to ethnicity, race and gender? How does gender become a relevant factor in acquiring prestige? What types of economic and artistic strategies do musicians develop to achieve artistic autonomy? Throughout the fellowship, the ER will conduct 35 in-depth interviews with mixed-background jazz musicians, undertake ethnographic fieldwork at e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Targeting the Human Myocardial Remodeling Process Using Novel Magnetic Force-Based Human Heart Tissue' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Cardiovascular diseases are responsible for the greatest proportion of deaths in people under the age of 70 and cost the EU €110 billion each year. A major cause of heart dysfunction following myocardial infarction is the extensive remodeling of the extracellular matrix (ECM), which leads to the formation of fibrotic scar and death of cardiomyocytes - a collective process known as myocardial remodeling. Diagnosis and treatment of this progressive pathological remodeling process are a top priority in modern healthcare. The project aims to develop novel 3-dimensional (3D) human Magnetic HEART tissue based on unique magnetic nanoparticles (MNPs), and includes two world firsts: (1) a model for long-term live monitoring of ECM remodeling and (2) a new generation of scaffold-free myocardial regeneration techniques. Innovative MNPs will be designed and synthesized to target and specifically label human cardiomyocytes and human cardiac fibroblasts. By applying an external magnetic field, the magnetically labeled heart cells will be accumulated to produce 3D human cardiac tissue, comprising its own biologically-produced ECM, which will offer a practical alternative to native human heart tissue. For the first time, live biochemical changes in cardiac ECM during physiological and pathological remodeling will be monitored using state-of-the-art Raman spectroscopy, which can reveal fundamental insights and improve the basic understanding of this process. This platform, which has not previously been reported, can be translated to treat the remodeled area in the heart by restoring structure and function to the damaged heart tissue, and marks a major breakthrough in magnetic targeting therapy for lesions localized deeper in the body. The outcome of this research has the potential to im
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Building an ecosystem for better monitoring and communicating of medication safety in pregnancy and breastfeeding: validated and regulatory endorsed workflows for fast, optimised evidence generation' (ConcePTION).

assistant: **Concept**

ConcePTION partners have united around a shared vision that we have a societal obligation to radically and rapidly reduce uncertainty about the safety of medication use in pregnancy and lactation.   What do we deliver? ConcePTION aims to create a paradigm shift in how we study medication safety in pregnancy. We will establish (1) a successful, sustainable open-science based EU non-proprietary ecosystem of public and private stakeholders, pregnant women and researchers to generate and disseminate timely and reliable evidence on drugs across maternal, neonatal and long term outcomes of medication exposure in pregnancy and breastfeeding (2) a catalogue with fully characterized data sources for rapid selection of suitable data sources; 3) operational, business, network, information and data governance models, (4) quality assured and tested methodological approaches, analytical tools and data platforms allowing for distributed analyses, (5) procedures and tools for collection of digital data and samples directly from pregnant women, (6) In vitro, in silico and in vivo models for prediction of drug transfer in human milk, (7) a biobank and analytical network for quantification of drug in human milk, (8) best practice documents endorsed by regulators and health authorities and (9) a web-based drug information knowledge bank.How do we deliver? (1) Experienced leaders, able to manage challenging networks and public-public or public-private partnerships. (2) Defragmentation by connecting all key stakeholders and EU networks in this area. (3) Re-use of data, tools and foreground from prior European commission funded projects. (4) Connecting to leaders of similar initiatives in the USA, Canada, Asia and other parts of the world. (5) Systematic consensus & endorsement building. (6)