RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Targeted R&D Policy'.

assistant: **Concept**

Radical changes in the global economy expose business sectors to major threats as well as to various new opportunities. Policy makers are required to target subsequent opportunities by enabling or promoting the business sector to take advantage of them. However, existing horizontal R&D policies focused on promoting R&D activity in individual firms are often lacking in this respect. Current and future scenarios require not only the design of new policies but also the adoption of a whole new type of policy process, namely the formulation of 'Targeted R&D' policies. Such policies go beyond market failure approach to identify strategic priorities as well as analysing system failures and imperfections impeding their successful implementation.. The aim of the TARGET project is to design and develop a structured and valorized set of guidelines & recommendations, cumulating into a toolkit, for formulating and implementing targeted R&D policies, with a focus on the life science/biomed sector. The toolkit will address issues such as: the ability to define strategic priorities, to evaluate technological gaps, to identify the elements within the national/regional innovation system responsible of achieving the selected priorities (including the missing elements), to identify potential system failures, to formulate effective policies and to reach coordination among the relevant policy makers/ministries. A consortium consisting of 8 partners from 6 different countries is assembled to implement the project. The consortium brings together public bodies, and research institutes, whose research will provide a sound base for decision-making in science and policy. The TARGET project will stimulate a mutual learning process among the consortium partners for the identification of the proper m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'NORmalize MusculoskeletAL LOadings to Avoid bony Deformities in children with cerebral palsy'.

assistant: **Innovation**

Muscle contractions in children with cerebral palsy (CP) cause abnormal musculoskeletal loading, which can lead to bony deformities. Deformities of the femur are commonly corrected by de-rotation osteotomies. In children, early clinical interventions, which aim to normalize the loading of the musculoskeletal system, could influence bone growth and prevent the development of bony deformities. To investigate this assumption, I will use musculoskeletal (MSK) models to calculate the loading conditions of the femur before and after Botulinum Toxin-A injections (BTI) in lower limb muscles. The obtained loading conditions will then be used as input for a mechanobiological finite element analysis (FEA) model to assess the impact of altered loading conditions on femoral bone growth. With this simulation platform, I will use the patient’s gait pattern and BTI treatment history to relate the loading conditions to the femoral deformities and compare these to the measured deformities from medical images. If BTI or similar load-modifying clinical interventions can be used to reduce the number of surgical corrections, it will decrease the burden on the child as well as decrease the socio-economic costs related to the treatment of children with CP.During my PhD at Griffith University (Australia), I compared different methods and models for clinical gait analysis and showed that MSK models can be confidentially used in children with CP. With this project, I strive to go one-step further and show that MSK loadings in combination with a mechanobiological model can be used to enhance our understanding of the impact of clinical interventions and, therefore, improve the treatment planning in children with CP. I am highly motivated to take on the challenge and acquire the new scientific and t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Preventing Respiratory Events through Proactive Assessment of Respiratory Effort' (PREPARE).

assistant: **Concept**

The incidence rate of Respiratory Compromise (RC) in hospital settings is 7% in intermediate/general care ward patients (107 million patients) and 30% in step-down postoperative patients (197 Million patients), at an average cost of €16,500 per event. It will cost the EU €31Bn by 2019. PMD’s technology will lead to a 20% reduction in the average patient length of stay, a 10% reduction in unplanned intensive care admissions, and a 5% reduction in liabilities from patient mortality by enabling early intervention of Respiratory Compromise (RC). This will be achieved by enabling the continuous and accurate monitoring of general ward patients respiratory rate (70% of the total patient population). The business opportunity is PMD Solutions (PMD), with its unique respiratory monitoring platform technology and its premier TRL7 CE marked product RespiraSense - the world’s first continuous respiratory rate monitor that is highly differentiated due to its ability to reject non-breathing artifact. This proposal, through the undertaking of clinical investigations, product optimisation, new product development and sales and marketing, will enable PMD to capture 0.4% of the market and sustain a 400% annual growth rate by 2020. It will lead to the generation of >€60M with sales across 3 continents including Europe, America and Asia and to grow the team from 10 to 21 within 3 years. PMD currently has 1 agreement with an Irish distributor and 7 Memorandum of Understanding (MoU) with other distributors across Europe with a further 25 other prospects. PMD is also in negotiations with the VP of marketing at each of the top 2 US (Welch Allyn, GE Medical) and the top Asian (Mindray) multinational patient monitoring companies. Globally hospital’s will save €775M over the next 3 years through t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Synthetic Bimodal Photoredox Catalysis:  Unlocking New Sustainable Light-Driven Reactivity' (SYNPHOCAT) under Horizon Europe.

assistant: **Objectives**

Solar light is an inexhaustible, abundant, and free reactant that can promote the construction and transformation of molecules. The chemistry community is particularly interested in photocatalysis, which uses light energy to promote a chemical transformation. Photocatalysts (PCs) play a key role in transformative light-driven processes by donating or receiving electrons to or from the target substrate. The selection and structural refinement of PCs can channel reactivity to diverse mechanistic pathways, but often proceeds via trial and error. Here, I will use structure-property relationships to: 1) define novel bimodal organic PCs able to catalyse thermodynamically demanding and opposite photoredox events exploiting their electronically excited state; 2) explore the PCs reactivity by means of their radical ions, going beyond conventional photoredox approaches; 3) capitalise on the new reactivity and bimodal way of action of the PCs to implement novel selective transformations of biological targets under physiological conditions. These project core concepts will be accomplished by the rational evaluation and optimisation of the PCs physicochemical and structural properties as well as the careful analysis of the mechanistic features subtending the light-driven chemical events. Overall, SYNPHOCAT will deliver new conceptual and experimental tools for the sustainable light-driven construction and functionalisation of biorelevant molecules, opening the way to a new dimension of sustainable light-driven chemistry.


**Keywords:** Photoredox Catalysis, Organocatalysis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Development of a design tool for structural reliability analyses of wind turbine components' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

Objectives The objective is the development of a computer code for wind turbine manufacturers and certifying bodies to be used partly as a tool for structural reliability analyses of wind turbine components and partly as a safety factors calibration tool. The computer code will apply to fatigue failure mainly and should be able to handle both measured and calculated 10 minutes load series. In addition it will explore how structural reliability methods can be used to analyze ultimate loads and ultimate strength instead of fatigue only. Finally, knowledge on structural reliability analyses and calibrating safety factors should be transferred to manufacturers (MICON and Aerpac) and certifying bodies (CIWI in the Netherlands via ECN, DNV in Denmark and Germanischer Lloyd in Germany). This will be done by carrying out a case study on the MICON M1500-600/150 kW wind turbine with Aerpac blades. Technical Approach A case study of the MICON turbine with Aerpac blades will be performed. This enables both manufacturers to implement structural reliability techniques relevant for their own particular case. Two Micon wind turbines with Aerpac blades have been chosen, one in Lutjewinkel (the Netherlands) and one in Emmerlev (Denmark). These turbines have been instrumented already for mechanical load measurements so some results of fatigue measurements will be available at the outset. The measurements in Denmark are nearly finished. The case studies consist of measuring, fatigue and ultimate loads and modelling of the turbine with time simulation programs. ECN will perform the measurements in the Netherlands and Risø in Denmark. The two case studies provide data for two different sites which together with the differences in measurement and simulation techniques give relevant input for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Continuation of the efforts of the local Enterprise Europe Network to further enhance the Innovation Management Capacity of Cypriot SMEs (KAM2CY 2)' in the context of a Horizon 2020 call.

assistant: **Objectives**

Continuation of the efforts of the local Enterprise Europe Network to further enhance the Innovation Management Capacity of Cypriot SMEs (KAM2CY 2)The project envisages the continuation of specialised coaching services addressing the innovation management capacity of Cypriot SMEs in order to increase the efficiency and effectiveness of investments in research, development and innovation.  The Research Promotion Foundation (RPF), is currently implementing a similar project funded by the EC (KAM2CY), which provides the local SMEs with Key Account Management services (KAM).The project aims to contribute to a better and more efficient connection of local SMEs along with the innovation chain. This will result to a smart growth of Cypriot SMEs and consequently of the Cypriot economy in general. The services will continue to be offered by RPF, as a bundle of additional specialised services, aiming to increase and accelerate economic returns of innovation.  RPF is the coordinating organisation of the Business Support Centre in Cyprus (BSC-Cy), the local member of the Enterprise Europe Network (EEN).


**Keywords:** innovation management
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Field Quantum Gravity Sensors' (FIQUgS), addressing dissemination and exploitation.

assistant: **Impact**

Gravimetry aims at unveiling the density structure of the undergrounds by measuring subtle changes of the local gravity acceleration. The first-generation of quantum gravity sensors (QGs) has received a strong interest from many customers, and the market is still growing. But the commercial potential and the positive-impact of the technology are not yet fully exploited because of several limitations such as transportability, robustness, user-friendless or high operation costs. To overcome the barriers that limit the operational utilization of field gravimetry and develop the solutions that will allow us to fully address the exploitable market, we propose to conduct in FIQUgS the development of several innovations, either at the technological level with improved QGs built upon a reliable and efficient supply chain, or in terms of operational methodology.The development of a next generation QGs product line, and the services associated for the conduction of field surveys, data acquisition and data inversion will allow to considerably develop our capability to address the market of advanced geophysics. The unique industrial and technological capabilities that will result from FIQUgS will positively contribute to several important societal objectives, especially the European Green Deal:- the new field QGs will allow for a reduction of the environmental impact associated to mining activities thanks to a reduction of drilling operations, and civil engineering where it will contribute to more efficient and resilient constructions.- they will contribute to an improved utilization of geothermal energies through the development of non-invasive monitoring capabilities of the energy reservoir.- they will be involved in CO2 storage operations and will contribute to the fight against
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Biomechanics, fluid dynamics and evolution of collective and cooperative motility of insect spermatozoa using microfluidic devices' under Horizon Europe.

assistant: **Concept**

Spermatozoa show great morphological diversity and share the function of fertilisation. They are often found as single cells, but in some organisms, such as insects, they can form aggregates ranging from two to hundreds of cells. One of the most intriguing parts of this phenomenon is the coordinated motility and improved swimming performance and reproductive success. Research on sperm motility in insects is still largely unexplored, with most studies focusing on vertebrates. The MOTIONSPERM project seeks to address this research gap by analysing the biomechanics and fluid dynamics of different types of sperm aggregates and insect species and placing these findings in an evolutionary context. The collective motility of sperm aggregates is influenced by both their cellular characteristics and the microenvironmental conditions of the reproductive organs where they swim. These include the properties of the reproductive fluids and the geometry of the organs. I will use advanced microscopy techniques, 3-D reconstruction of reproductive tracts, and innovative measurement of fluid viscosity and viscoelasticity to perform microfluidic device assays that simulate realistic reproductive models, allowing us to observe sperm motility under conditions that closely mimic their natural environment. Reproductive traits, including sperm motility novelty, will be investigated in a temporal phylogenetic frame. This project will contribute to a deeper understanding of insect aggregate sperm motility and its impact on fertility, sperm competition, evolution and cooperative cellular functions. In addition, the project will produce relevant and high-impact research results, potentially applicable to sustainable agriculture, future biomedical applications and public health plans in the EU. The
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Cardiac energetics in silico: micro-compartmentation of adenine nucleotides and the cross talk between organelles', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

Ischemic cardiomyopathy and heart failure represent a leading cause of degradation of quality of life and death in EU countries. Although major advances have been made in the treatment of coronary artery disease and heart failure, the mechanism of these my ocardial disorders remains poorly understood.The general aim of this project is to study alternations of mitochondrial energetics, micro-compartmentation of adenine nucleotides, the crosstalk between intracellular organelles and cellular energy transfer in health and disease using mathematical modeling.The specific goals of this project are- to describe microcompartmentation of adenine nucleotides and the crosstalk between organelles in the cardiac muscle cells and- to apply the knowledge acquired in studies of isolated mitochondria and skinned cardiac cells to analyze energy transfer in the beating heart.For this, we will continue our mathematical modeling of intracellular energy transfer and analyze the energy fluxes estimated for beating heart. The research will be performed in tight cooperation with several national and EU laboratories. The expected results are as follows. Firstly, through application of mathematical modeling in analysis of the experimental data provided by our collaborators, we expect to clarify localization and the role of intracellular diffusion restrictions in the formation of microcompartments in cardiac muscle cells.Secondly, by applying the knowledge acquired in studies of isolated mitochondria and skinned cardiac muscle cells to analyze energy transfer in the beating heart, we should be able to clarify the mechanisms underlying the modification of the energy pathways in normal beating hearts and in the hearts with partly inhibited ATP synthase. From clinical perspective, the developed mode
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'A Gamma-ray Infrastructure to Advance Gravitational Wave Astrophysics' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

When galaxies merge, do their central supermassive black holes also merge?  How does the merger affect star formation and the evolution of galaxies? How does physics beyond the Standard Model of particles affect the Universe? The detection and characterisation of low-frequency gravitational waves (GWs) will address these fundamental and longstanding questions of astronomy and cosmology. Supermassive black holes at the centres of merging galaxies are expected to form binary systems whose orbital motion generates GWs. A cosmological population of such systems combine to build up a GW background (GWB). Such a GWB is also expected if the Universe went through an inflationary period, providing a GW map just moments after the Big Bang. Pulsar timing arrays (PTAs), which are ensembles of extremely stable millisecond pulsars (rotating neutron stars), can be used to study this GWB. Searches for the GWB have typically used sensitive radio telescopes. However, radio data exhibit complex noise processes, predominantly arising from the interstellar medium (ISM), that limit its sensitivity and introduce bias. Gamma rays are immune to the effects of the ISM and a gamma-ray PTA can overcome several of the limitations affecting radio data. GIGA will (a) establish a gamma-ray PTA and independently detect the GWB, (b) develop advanced inference techniques to distinguish its astrophysical origins, (c) measure properties of the ISM through multiwavelength studies, and (d) explore energy-dependent couplings of dark matter. Through these avenues, GIGA will also maximise the sensitivity of radio PTAs and provide crucial validation of their measurements.The detection of the GWB will provide the first stringent constraints on the dynamical evolution of supermassive black holes and their host gal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Foundations of Web Data Management' to be submitted under Seventh Framework.

assistant: **Abstract**

We propose to develop a formal model for Web data management. This model will open  new horizons for the development of the Web in a well-principled way, enhancing its functionality, performance, and reliability. Specifically, the goal is to develop a universally accepted formal framework for describing complex and flexible interacting Web applications featuring notably data exchange, sharing, integration, querying and updating. We also propose to develop formal foundations that will enable peers to concurrently reason about global data management activities and cooperate in solving specific tasks and support services with desired quality of service.  Although the proposal addresses fundamental issues, its goal is to serve as the basis for ground-breaking future software development for Web data management.