RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Revealing Extinction Risk through Comparative Genomics and Artificial Intelligence' (REVEAL) targeting Horizon Europe.

assistant: **Abstract**

Understanding species extinction risk is a crucial goal in Evolutionary Biology and a contemporary societal challenge. The standardmethod for assessing extinction risk, the IUCN Red List, focuses on external threats and overlooks genetic factors. Despite some weakand variable correlations, genetic diversity offers insights beyond the Red List, potentially resulting in an underestimation ofextinction risk. Genomic data, generated rapidly through initiatives like the Bird 10,000 Genomes Project, has the potential toenhance assessments by revealing historical population demography, genetic diversity, and the genetic load of deleteriousmutations. Recently, there has been excitement about the potential of reference genomes in conservation genomics. However, theactual potential and limitations of single reference genomes in informing conservation strategies remain unexplored. To address thisgap, I propose a comprehensive approach, REVEAL, which integrates comparative genomics and individual-based simulations withina robust Artificial Intelligence (AI) framework. The proposal comprises three steps: (i) simulating extinction risk using a broadparameter space with a dataset of at least 3,825 bird genomes generated by the B10K consortium, (ii) training AI models to recognisegenomic signatures associated with extinction risk, based on the previous simulations, and (iii) evaluating the potential andlimitations of single reference genomes for extinction risk assessment, using the trained AI models. In particular, I will focus on avianspecies with diverse geographic ranges and ancestral population sizes in order to compare extinction risk predictions, consideringboth spatial dynamics and temporal dynamics. REVEAL seeks to move beyond conventional assessments and improve ourunderstand
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Homogeneity and cross-contamination measurement in feed industry' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

For the industrial production of feed, a correct mixing resulting in an homogeneous feed and the avoidance of cross-contamination (carry-over of additives) from previous batches into the following feed batch contribute significantly to the quality and safety of the feed. However available methods for measuring homogeneity and cross-contamination encounters several difficulties and suffers from many disadvantages. This project aims at designing a new method for homogeneity and cross-contamination measurement in feed industry. To reach this objective, the consortium will test new potential methods; select them through successive trials from laboratory and pilot scale trials to industrial validation; and simultaneously compare these new methods to six existing ones to finally select the most suitable method, which could be further developed as a European standard.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Spectroscopic and computational investigation of the energetics of mixing in silicate solid solutions' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Research objectives and content  The primary scientific objective of the project is to produce a fully quantitative description of the local structural state of the binary silicate solid solution diopside (CaMgSi2O6) - Ca-Tschermak (CaAl2SiO6). In a new approach, a combination of the most up-to-date experimental techniques and computational simulation methods will be used to determine the structural and energetical change associated with the mixing process on an atomistic scale.The experimental techniques to be used are: 1) 29Si MAS NMR spectroscopy to characterise the degree of order of the samples on a local basis and 2) hard mode infrared spectroscopy (HMIR) for probing local structural distortions.The computational techniques to be used are 1) lattice energy calculations for modelling the energetical changes resulting from the mixing process and interaction energies between cations on neighbouring structural sites and 2)Monte Carlo models for the simulation of configura- tional effects such as the configurational entropy of mixing. The results of this study will be used to develop a concise picture of the dominant factors governing the mixing process of solid solutions on an atomistic scale. Training content (objective, benefit and expected impact) During the experimental part of the project the applicant will be trained in the hands-on application of the MAS NMR spectroscopy and the new method of HMIR spectroscopy. The theoretical part will train her in the backround and use of computational methods applied to solids. The combination of experimen- -tal and computational skills acquired during the course of the project represent a particularly valuable and timely training for future research in either academia or industry. Links with industry / industrial relevance
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Research for GaN technologies, devices, packages and applications to address the challenges of the future GaN roadmap'.

assistant: **Concept**

The main objective of UltimateGaN is to safeguard Europe’s leading position in terms of power semiconductors and high performance RF applications by driving an innovative breakthrough change with the next generation of GaN-technologies. Several predecessor projects are the basis for the availability of the first generation of European based GaN-devices, also revealing that the challenges of these technologies have been heavily underestimated. This makes the high potential of GaN clearly evident to overcome the persisting threats of higher electric fields, current densities and power densities related to the necessity of device shrinkage. The new concept of following a vertical approach to address research through the entire supply chain of technology, packaging, reliability and application will enable a significant improvement of efficiency that goes beyond the limits of silicon based semiconductors in combination with packages that fully utilize the shrink-path of power GaN devices and which are not ready as of today.UltimateGaN’s unique approach addresses, among others, the following innovative applications with the scope to enable digitalisation and energy efficiency for 5G, Smart Grids and Smart Mobility that goes hand in hand with a significant reduction of the CO2 footprint:•Extremely efficient server power supply enabling lower energy consumption in data centres •Benchmark Photovoltaic inverters in terms of efficiency and size to foster the use of renewable energies •Affordable 5G-Amplifiers up to mm-wave enabling a faster 5G rollout •GaN powered LIDAR application to enable autonomous driving •Highest efficiency µ-Grid-converters and On-Board Chargers The global state-of-the-art first generation GaN devices are mainly based on US and Asian suppliers. Only a coope
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Ubiqutek Electrical Weed Control (UEWC): An advanced electrical weed control device to be integrated with existing agricultural equipment, yielding a zero chemical, organic result at a reduced cost'.

assistant: **Objectives**

Reduced herbicides! Ubiqutek presents the first to market agricultural electrical weed control, Ubiqutek Glide a cost-effective, safe to use and environmentally friendly solution to be integrated to existing technology manufacturer’s platforms. Benefiting the agricultural market, Glide successfully controls weeds, whilst reducing operational costs and the industries use of herbicides and replacing with an organic process that maintains soil moisture and nutrients and increases the markets operational capability.Having already developed Ubiqutek Touch, a horticultural and amenity electronic weed control device that has been well received by the market, we are well placed to adapt our technology for the agricultural market. Weeds are controlled largely for food production, although there are numerous applications for aesthetic, safety and recreational purposes. End users can range from individual farmers through to large civic authorities. Weed control is economically significant: removing weed control from food production could cost the UK economy €99.3Bn, whilst dealing with invasive species in the UK in 2010 cost €2.41bn.With herbicides being legislated against and given the increasing global food requirements, alternative weed control technology is essential in the prevention of unsustainable food inflation. This Horizon 2020 Phase 1 project will allow us to establish contact with European agricultural manufacturers of existing platform technology and establish their need for this technology in the marketplace they operate in and the size of their market place, validating our technology and confirming our route to market. We will also complete IP protection activities and prepare for Phase 2 application.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'IgA-based oral therapy for protection of piglets against infection with enterotoxigenic E. coli.' (ImmunoFarm).

assistant: **Innovation**

Postweaning diarrhoea (PWD) in pigs is responsible for important economic losses in the global pig rearing industry. This illness is predominantly caused by enterotoxigenic E. coli strains carrying the F4 (ETEC-F4) and F18 (ETEC-F18) fimbriae. There is no treatment available to fight PWD except using antibiotics. However, the prophylactic use of antibiotics is forbidden in Europe and is expected to become forbidden in the rest of the world because of increasing abundance of resistance genes. Delivery of sIgA to mucosal surfaces as passive immunotherapy agent is a very promising strategy to prolong maternal lactogenic immunity against post-weaning infections. The aim of this project is to produce sIgA-like anti-ETEC antibodies in a cost-effective platform. Twenty different anti ETEC-F18 antibodies in a sIgA-like format will be engineered from phage display-selected variable domains (VHHs) currently available in the host institute. The synergistic or additive neutralisation effect of oligoclonal antibody cocktails will be evaluated using ETEC-F18 in vitro villus adhesion assays. The different antibodies will be produced first by transient expression in Nicotiana benthamiana and second in seeds of Arabidopsis thaliana transformants. An in vivo ETEC-F18 challenge will then be performed using two groups of piglets, one receiving the most effective seed-derived feed formulations and the other one receiving regular feed (negative control group). The sIgA antibodies of the elite oligoclonal formulation will then be transferred to biosafe soya seeds as production platform. These steps will lead towards the development of scalable procedures to obtain a cost effective bulk production of a feed based prophylaxis against ETEC.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'DEcoding Metabolic Effectors in plant sTress Response and Acclimation' under Horizon Europe.

assistant: **Concept**

The European Commission aims at promoting agricultural innovation while preserving biodiversity and without increasing arable land surface. Understanding how plants respond to stress is therefore vital to design new, improved agricultural solutions that meet these requirements.General and conserved plant stress responses to pathogens rely on systemic propagation of Calcium (Ca2+) signalling and reactive oxygen species (ROS) from the site of attack to distant organs. An unexpected, essential link between primary metabolism (i.e. NADP/H production), long-distance Ca2+ signals and ROS propagation was recently brought to light, thus opening a new line of fundamental research (i.e. the metabolic regulation of plant stress signalling) and suggesting that modulation of NADP metabolism can boost plant defences.DEMEtRA (DEcoding Metabolic Effectors in plant sTress Response and Acclimation) aims at obtaining a deep characterization of this metabolic regulation of plant signalling in response to bacterial pathogens by combining biochemical and cutting-edge imaging techniques. This project will produce a thorough characterization of the NADP/H production mechanism and of the perturbations of long-distance signalling caused by a shortage of NADP/H. Finally, it will allow engineering new solutions to improve plant stress responses against pathogens, by acting on NADP/H metabolism. Thus, DEMEtRA will quickly advance fundamental research on plant stress signalling and guide biotechnological applications to improve conserved, natural defence mechanisms in crop plants.


**Keywords:** Arabidopsis, calcium signalling, NADP, ROS, imaging, calmodulin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The SUPPMIL project investigates the drivers of individual politicians and political parties’ support for United Nations and NATO military operations abroad.' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Why do national political parties and individual members of parliament (MPs) adopt different attitudes towards UN and NATO operations? To tackle this question, the project adopts a multi-method approach and brings together quantitative text analysis and case-studies investigation. First, the quantitative text analysis addresses thirty years of parliamentary debates in Canada, Germany, Italy, UK, and US, and discussions in the UN Security Council (UNSC) and in the North Atlantic Council. Second, the project entails case studies on two UN missions, the UN Organization Stabilization Mission in the DR Congo, and the UN Interim Force in Lebanon and two NATO missions, Kosovo and Afghanistan. Results of the multi-method analysis enrich the theoretical debate about the factors that explain levels of support for military missions: the elaboration and the empirical testing of two unified theories for MPs and political parties’ positions on armed interventions abroad is a key innovative contribution. Second, the case-studies analysis provides novel insights about states and parties’ rhetoric and behaviour, contributing to relevant academic debates on international norms, rhetorical political analysis, and organised hypocrisy. The theoretical implications range from the political salience of different missions to the discrepancies of Foreign Policy positions over the domestic-international divide. In addition, the project provides significant methodological improvements. The combination of quantitative with qualitative text-analysis tools offers intriguing insights about the strengths and weaknesses of the two approaches and about the potential for their interaction. Finally, the project aims at refining the rigorousness of Bayesian process tracing, building systematic rules to ass
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Mechanobiology of METAstatic and DORMant cancer cells in bone marrow lesions' (META-DORM), addressing dissemination and exploitation.

assistant: **Impact**

While cancer survival rates have improved significantly in recent years, survival decreases dramatically after tumour metastasis. One of the most common sites for metastatic tumours to develop is bone. Intriguingly, evidence suggests that once they have invaded the bone marrow, individual metastatic cancer cells can persist for years in a quiescent or “dormant” state, and are resistant to both radiation and chemotherapy treatment. These dormant cells can reside for months or years while the cancer is in remission, and then “reactivate” without warning to form new, usually fatal, skeletal lesions. Tumour cells achieve this by “hijacking” the normal bone remodelling cycle, a homeostatic balance between bone formation and resorption, to form a metastatic niche within the marrow. However, the signalling mechanisms that cause metastasis and dormancy, particularly in such a mechanically active environment, are poorly understood. Therefore, the goal of this project is to investigate the chemical and physical interactions between bone and cancer cells, both during dormancy and mechanical stimulation, to provide new insight into bone metastatic lesions and explore novel therapeutic targets to prevent cancer metastasis. This will be achieved by culturing specific bone and cancer cell types together for the first time to observe changes in their signalling and behaviour. Dormancy will also be induced, to observe its effect on changes in signalling. Mechanical stimulation will be applied to investigate whether the complex mechanical environment of the bone marrow plays a role in cancer metastasis. Finally, a specific cellular mechanosensor, the primary cilium, which has been implicated in the development of cancer and is known to be involved in bone formation, will be investigated.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Near-field Enhanced Accuracy Tracking for 6G Networks' (NEAT-6G) targeting Horizon Europe.

assistant: **Abstract**

As the technological world marches ahead, the advent of the sixth generation (6G) networks promises unprecedented advancements in communication capabilities. One of the core components of 6G systems will be the inclusion of various large array structures such as the extremely large antenna array, reconfigurable intelligent surface, and cell-free multiple-input multiple-output. Ttraditional positioning and tracking methodologies (which are based on far-field signal models) are ill-suited for these innovations. This is mainly caused by curved wavefront in the near-field models. Consequently, the conventional methods for positioning both passive objects (e.g., walls) and active users (e.g., phones) will be severely degraded when the far-field assumption does not hold. On the other hand, the radio signals optimized for positioning and sensing in the far-field are sub-optimal in the near-field regime. To address this gap, this research aims to develop novel positioning and tracking methods tailored explicitly for the near-field environment of these large array structures. To this end, three work packages (WP) are conducted. WP1 is to design optimal signal waveforms for positioning and sensing with large and/or sparse antenna arrays that can make full use of the near-field features. WP2 is to develop phase-coherent sensing and tracking methods for non-isotropic and extended targets. WP3 is to develop algorithms for carrier-phase based positioning and tracking of active targets, by using the near-field signals transmitted by them. This research intends to solve these challenges through the development and implementation of innovative algorithms and methodologies, such as compressive sensing, convex or non-convex optimization, and machine learning, establishing a dedicated fram
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Classical biological control with predatory mites - the significance of complex trophic interactions'.

assistant: **Concept**

Reducing pesticide inputs requires alternative, e.g. biological, pest control measures. Biological control of spider mites usually requires multiple inundative releases of predators. The only permanent pest reduction through inoculative releases of predatory mites was achieved on cassava in Africa. Te inoculative use of predatroy mites is hampered by a poor understanding of their desired ecological/biological attributes. Ecological theory has considered the importance of desired attributes for systems involving two trophic levels, but it is increasingly clear that attention must be paid to host plant traits and alternative food. The study of food webs and its bearing on biological control is in its infacy. In this poroposal, the cassava case will be used as a paradigm to hypothesize on the importance of complex trophic relationships for success in biological control. The hypotheses concern (1) the importance of host plant attributes for pest suppression and (2) effects of interactions between natural enemies on control success. A training in the fundaments of ecology/population biology and its application in biocontrol is a prerequesite to enhance sustainable agriculture in Portugal. Reducing pesticide use will have a positive impact on the environment and make crop production more cost effective. Commercial production of biocontrol agents.