RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Emotional Musical Signals' (EMUSIG), addressing dissemination and exploitation.

assistant: **Impact**

The emotional power of music is a force we reckon with on a daily basis. Bubbly music in advertisements entices us to buy products. Tranquil music in medical waiting rooms evokes calm and diffuses anxiety. In spite of its extensive influence, there are still many open questions about how music impacts our emotions. One emotion in particular has been largely overlooked in music and emotion research: fear. The lack of research is surprising given the important role fear plays in society. Fear-based mental disorders are the most widespread, negatively impacting the lives of millions worldwide. Fear drives our daily behaviors and thus is used frequently to spread beliefs for political gain. Given its relevance, there are many benefits for deepening our understanding of fear. Music, a powerful emotional influencer, could be the ideal tool for furthering our knowledge of fear. This groundbreaking, interdisciplinary action will unlock the potential of music as a platform for fear research through the combined use of methods from cognitive neuroscience, behavioral psychology, and music theory. Specifically, my research objectives are to create a new multicultural database of scary music excerpts, catalogue cultural and biological musical fear signals, and synthesize the results of this research into a comprehensive report on musical fear signaling. My training in music theory and cognition methods and my expertise in film music make me the ideal person for this action. The interdisciplinary, state-of-the-art research environment at the Cognitive and Affective Neuroscience Laboratory at the University of Zurich is the perfect location for this work. At this pioneering lab in the field of vocal and music perception, I will be trained in cognitive neuroscience methods (fMRI & eye
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Deciphering the functions of the Aurora-B in the molecular mechanisms of chromosome segregation and the epigenetic program of male germ cells' (2002-2006) targeting Sixth Framework.

assistant: **Abstract**

The goals of my proposed research are to elucidate the functions of the Aurora-B kinase in chromosome segregation and epigenetic reprogramming during spermatogenesls. This research promises to provide new information pertaining to infertility and diseases arising from chromosomal abnormalities such as cancer and Down syndrome. In mitotic cells the Aurora-B kinase has key functions in chromosome dynamics, chromosome condensation and chromatin modifications. However, its function in mammalian meiosis is unkno wn. I propose to investigate the role of the Aurora-B kinase in mammalian spermatogenesis using newly engineered transgenic mouse lines with meiotic-specific promoters that either over-express Aurora-B, or express a non-functional form that acts as a domin ant negative. Immunofluorescence and electron microscopy will be used to analyse the alignment, synapsis and segregation of the chromosomes in transgenic versus wild type mice. In addition to its role in chromosome dynamics, the Aurora-B kinase is likely t o have an epigenetic function in germ cells. The field of epigenetics involves the study of heritable modifications that do not alter the DNA code, but instead control gene transcription through chromatin structure via histone modifications. Epigenetic mod ifications in the germline are remarkable because they can control gene expression from one generation of an organism to the next. Aurora-B is known to phosphorylate, histone H3. This phosphorylation has been linked to chromatin condensation and epigenetic regulation of gene expression. To investigate the role of Aurora-B in the epigenetic program of sperm cells I will probe for differences in chromatin modifications between transgenic and wild type animals.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'European eInfrastructures Observatory' under Seventh Framework.

assistant: **Concept**

Within the EARNEST foresight study, a prelude but systematic benchmarking undertaking was conducted, with the spotlight on the Research and Education Networking Infrastructures that resulted to a framework called Research and Education Development Index – REDI, as a first step of measuring the progress of eInfrastructures. This activity stimulated substantial interest within the eInfrastructures community as well as an extended group of stakeholders, including the European Parliament.Alongside, the issue of benchmarking has been raised high in the EC policy agenda in several recent occasions as vital for assessing the impact of eInfrastructures at EU level and beyond, with the INFRA-2010-3.3 topic materializing policy into specific call-for-action.Responding to this, the eNVENTORY project suggests the formation of a European eInfrastructures Observatory, a single-entry-point and one-stop-shop of a standardised database, accessible via an advanced web platform and capable of representing multiple primary and convoluted indicators and benchmarks through intuitive, interactive and user-friendly mappings, plots and graphics, and open to the eInfrastructures stakeholders and to the public-at-large to generate personalized lists, rankings, and cross-comparisons, over time and across regions, in a fully modular and customizable way.The eNVENTORY project will extend prior benchmarking by including all core components of eInfrastructures (i.e., computing, communication and services) and will build the indicator databases from various international repositories. It will carry out extensive consultation with eInfrastructures stakeholders and research and innovation indicator experts, and will eventually deploy a prototype web platform dealing with a critically-selected subset of i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'A novel synthetic data generation platform that produces private, secure and robust synthetic data for AI use cases' to be submitted under Horizon Europe.

assistant: **Abstract**

The age of the artificial intelligence (AI) revolution has arrived, bringing with it numerous opportunities across key industries, including healthcare, banking, and retail. Recent studies indicate that AI has the potential to increase global GDP by  EUR14.03 trillion by 2030. However, the effectiveness of AI systems has thus far been limited by a lack of access to high-quality data without infringing on privacy rights. Poor data quality—characterized by incompleteness, inaccuracies, outdated information, or irrelevance—can lead to biased predictions and erroneous decisions, affecting up to 80% of AI projects.To address these issues, synthetic data has emerged as a potential solution. Synthetic data is artificially generated information that mirrors the statistical properties of real-world data. This data can be freely processed and used in AI model development without risking privacy breaches. However, until synthetic data can overcome its current limitations, its use remains restricted. These limitations include avoiding biases present in the original data, generating synthetic data that mimics very complex relational databases, and effectively satisfying deterministic rules.At Aindo, we have developed SyDAi, a novel synthetic data platform that empowers companies to generate high-quality and high-privacy synthetic data. This breakthrough aims to democratize and accelerate AI innovation, enabling all industries to actively participate in the AI revolution. Unlike many existing solutions that focus on specific data types or lack the ability to handle certain statistical dependencies, our platform can generate synthetic data with advanced data formats. The innovation of this innovation has recently led to SyDAi being recognized independently by the United States Nationa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Transfer of knowledge in biochemistry and molecular biology of cellular membranes in normal cells and in pathological conditions' (MEMBRANE-TOK), addressing dissemination and exploitation.

assistant: **Impact**

Our aim is to transfer the methodology and principles developed at one laboratory to the other institutions and by this cooperation perform multidisciplinary studies not possible on individual basis. The host institution established a strong research capacity in lipid biosynthesis, molecular genetics and proteomic, the Warsaw group is the only in the world capable of synthesizing a number of labelled lipid intermediates and end products while the Krakow group has developed a novel and unique model membrane system and methodology for its investigation. By this cooperation the potential of the host institute will increase greatly. The two Polish institutions have a highly valued position in the scientific community which is however restricted to a narrow field.Our aim is that they acquire the complementary knowledge and methodology in membrane research developed in the host laboratories and with new fields they reach a leading position. The scientific aim of this proposal is to investigate the structure and function of biological membranes, especially the mechanism of biosynthesis and breakdown. The knowledge in this field is necessary for understanding normal cellular functions and also of basic importance in study of large group of diseases such as atherosclerosis and diabetes. We have a strong scientific position in research of membrane turnover and order to keep up and further strengthen our output in this field we have to acquire new principles and methodology of multidisciplinary nature, methods which are related to fields of biochemistry, molecular biology, analytical and physical chemistry, cell biology and organic synthesis.The Polish partners have all the basis and qualifications to became the outmost experts in membrane research if they get the appropriate supp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Development of new-to-nature reactions under the concept of synergistic catalysis through the design of novel cobalt-based artificial metalloenzymes.' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Artificial metalloenzymes (ARMs), that is, designed enzymes containing a synthetic metal co-factor within a protein framework, locates itself as a promising area of research for the discovery and development of new transformations. We set our attention in cobalt complexes as co-factors, a first-row, earth-abundant, and non-toxic metal that is currently underexplored in ARMs. Cobalt complexes present a highly versatile chemistry, including they ability to participate in allylic functionalization reactions, an important transformation for the pharmaceutical industry as can deliver structural frameworks that are widely spread in biological active compounds. Allylic functionalization reactions are underdeveloped in bio-catalysis, and the expansion of important homogeneous reactions, as the before mentioned, into the realm of enzymes is an absolute necessity for the development of sustainable chemistry. Co-ARMs (Cobalt-containing ARtificial Metalloenzymes) proposal aims to create new generations of ARMs relying on the unique reactivity of synthetic cobalt complexes in allylic substitution reactions, an unknown reaction in enzyme catalysis and an underexplored metal for the discovery of new-to-nature reactions. The proposal balance between host expertise (Dr. Gerard Roelfes) in bio-inorganic and chemical biology, and the researchers skills (Dr. Franco Della-Felice) in synthetic organic chemistry. The result is a cooperative field where two different branches converge with the aim to develop new concepts and environmentally compatible tools in chemistry to access organic frameworks of high significance to the pharmaceutical and agrochemical industries.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Gridded Ion Engine Standardised Electric Propulsion Platforms'.

assistant: **Objectives**

The consortium proposes an innovative activity to develop, build and test to TRL5 the first European Plug and Play Gridded Ion Engine Standardised Electric Propulsion Platform (GIESEPP) to operate Airbus Safran Launchers and QinetiQ Space ion engines. These are the only European ion engines in the 200-700W (LEO) and 5kW (GEO) domains that are space-proven, and the consortium’s intention will be to improve European competitiveness and to maintain and secure the European non-dependence in this field. The project will design and develop a standardised electric propulsion platform for 200-700W and 5kW applications, which has the capability to run either Airbus Safran Launchers or QinetiQ thrusters. In addition, the 5kW electric propulsion system will be designed to allow clustering for 20kW EPS for space transportation, exploration and interplanetary missions. In order to cope with challenging mission scenarios, Dual Mode functionality of the thrusters will be realised. This ensures that the beneficial high Isp characteristics of Gridded Ion Engines are maintained, whilst also offering a competitive higher thrust mode. The GIESEPP systems will not be limited to xenon as an operating medium; assessments will be performed to ensure functionality with alternative propellants.The approach to system standardisation and the resulting solutions will provide highly cost competitive and innovative EPS for current and future satellite markets, whilst meeting the cost efficiency requirements. The proposal will describe the roadmap to higher TRL by 2023-2024, providing a cost competitive EPS. Finally, the proposal will address efficient exploitation of the results, demonstrating how the activity will positively increase the impact and prospects for European Ion Engines and the European
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Evolutionary immunology: using insect models to unravel STING-dependent conserved and innovative antiviral strategies' (Evo-immuno) under Horizon Europe.

assistant: **Objectives**

As we have seen with the emergence of viral pathogens like Ebola, ZIKA and SARS-CoV2, our societies are, and will continue to be, confronted to unknown and perilous viruses. To prepare for this, we propose to explore the diversity of antiviral genes in animals. Important signaling nodes have been conserved throughout evolution and regulate expression of antiviral genes that evolve dynamically in response to viral pressure. Because this occurs in parallel between different lineages, each animal has a unique arsenal of antiviral genes, with a core of conserved genes, but also taxon-specific genes, which represent an unexplored resource of potentially unique antiviral mechanisms. Insects, the largest group of animals, present high potential for such project but lack of information on the viruses infecting most of them prevented broad investigation up to now. Our discovery that the cyclic dinucleotide (CDN) cGAMP triggers a strong STING- and NF-B-dependent antiviral protection in drosophila, provides for the first time a handle to access the repertoire of induced antiviral genes in insects. We will exploit the assets of the drosophila model to address the function of cGAS-like receptors and the CDNs they produce. We will use RNA sequencing of cGAMP-stimulated insects and evolution-guided paradigms to identify among the STING-regulated genes candidates for functional antiviral screens in insect and human cells. Hits will be characterized to understand their mode of action. As proof of principle, we will study the function of Nazo, a fast-evolving STING-regulated gene duplicate in drosophila also strongly upregulated by interferons in bats. Overall, this project will provide a unique evolutionary perspective on the STING pathway and will lay the foundations for exploitation o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Enhance New Approaches in BioBased Local Innovation Networks for Growth' (ENABLING).

assistant: **Innovation**

ENABLING is the initiative of 16 partners in 13 EU and associated (IL, NO) countries. The main goal is to support the spreading of best practices and innovation in the provision (production, pre-processing) of biomass for the BBI (Bio-Based Industry). In particular, ENABLING aims at creating appropriate conditions for the development of efficient biomass to BBPs (Bio-Based Products and Processes) value chains. The consortium’s vision is that Europe bears a huge potential for optimising the supply of biomass into innovative bio-based processes and products. Upscaling biomass production and pre-processing, and combining streams towards the BBPs with those of more traditional bioenergy chains would enhance at least three interlinked types of impact. a) biomass production gains scale to meet higher demand in both sectors (bioenergy and the BBI); b) the reinforcement of biomass supply for the BBI benefits smaller BBI players, helping them diversify and consolidate biomass input sources; c) reinforcing the biomass and BBPs linkages may contribute to job-creation, due to the increased need for specialised workers. To realise such potential, ENABLING also anticipates its longer term exploitation pathways. In the intention of the consortium, the project should aggregate and engage partners for the establishment of a permanent innovation brokerage platform, likely to become in the future, one of the main marketplaces and innovation transfer accelerators at European level. In this sense, the project organises its work around two building blocks: one relates to animating the stakeholders (on the farming and BBPs sides), identifying best practices, turning them into easy to access content (in the EIP format) for their potential users and providing stakeholders with coaching and guid
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Center for Application of Ion Beams to Materials Research' (AIM).

assistant: **Concept**

In continuation of transnational user access programs funded under FP4 and FP5, AIM is devoted to transnational European user access for application-oriented materials research and services using ion beams. It will be open for scientific studies and for the implementation of ion beam technologies in industry. The infrastructure offers a variety of devices for ion beam analysis and ion beam modification of solid surfaces, embedded in a strong materials science environment, thus constituting a unique facility in Europe. Fields of application cover R&D areas such as electronic and magnetic materials, biomaterials and polymers, and materials, which are resistant against mechanical wear or chemical attack all areas where ion beams act as powerful nanotechnological tools.The infrastructure combines 3 electrostatic accelerators with ion energies up to ~50MeV, 3 ion implanters providing ions at sub-keV to MeV energies, and devices for ion beam, plasma assisted thin film deposition and plasma-based ion implantation and a focused ion beam apparatus. Partly unique special facilities include simultaneous ion implantation from 2 accelerators, high-resolution ion-beam analysis, and real-time, in-situ process diagnostics by means of ion-beam analysis. At least 250 shifts of each 8hrs beam time will be offered to AIM Users annually.Users will be supported by the scientific and technical staff of the infrastructure during planning, performance, evaluation and interpretation of the experiments. Preferential access will be given to new Users of the infrastructure, projects involving young scientists, and Users from countries where similar ion beam facilities are unavailable. Users from the new member states and candidate states are expected to share are large fraction of the access being