RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Personalised Guidance Services for Optimising lifestyle  in teen-agers through awareness, motivation and engagement'.

assistant: **Objectives**

Obesity and other lifestyle-related illness are among the top healthcare challenges in Europe. Obesity alone accounts for up to 7% of healthcare costs in the EU, as well as wider economy costs associated with lower productivity, lost output and premature death. Obesity in younger age is an alarming predictor for obesity in adulthood, but also entails short term health complications in juvenile age along with greater risk of social and psychological problems.Knowing how to stay healthy is not enough to motivate individuals to adopt healthy lifestyles, but relevant progress can be achieved through the use of incentives delivered through a combination of processes and mobile technologies.Recognizing the effectiveness of this approach, the PEGASO project will develop a multi-dimensional cross-disciplinary ICT system that will exploit sophisticated game mechanics to motivate behavioral changes towards healthier lifestyles and prevent overweight and obesity in the younger population.The project relies on ICT technologies to implement a framework for the promotion of an health service based on three main features: individual&environmental monitoring, including wearable sensors, mobile phone and multimedia diaries for the acquisition of physical, physiological and behavioural attributes of participants; feedback to the user, presenting personalised healthy options for alternative lifestyles; social connectivity, encouraging involvement in social network experience sharing and social engagement. For the system development, a user centered approach, social and networked games and online education will be used. PEGASO will be tested with over 300 adolescents  in three EU member states (Spain, Italy, UK).The development of PEGASO project will mobilize a wide stakeholders' ecosystem
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Sustainable Nutrition Research for Africa in the Years to come' (SUNRAY), addressing dissemination and exploitation.

assistant: **Impact**

This is a critical time for nutrition. Malnutrition rates remain high, particularly in sub-Saharan Africa where only nine out of 46 countries are on track to achieve the first Millennium Development Goal target of a 50% reduction in underweight prevalence among children under five years. Despite the huge cost of malnutrition, investment in the nutrition sector has been insufficient. There has been a renewed interest in nutrition recently, however, and it is a potentially opportune moment for investing in nutrition research.The SUNRAY (Sustainable Nutrition Research for Africa in the Years to come) project will produce a new, sustainable nutrition research agenda for sub-Saharan Africa based on five concepts.1)Future landscape: Emergence of new nutritional challenges due to changes in the environmental landscape.2)Sustainable and broad-based solutions: Integration of nutrition research within other sectors to ensure sustainable solutions.3)African centre of gravity: Identification of research opportunities and constraints by African institutions.4)Broad stakeholder involvement: Strengthening of the link between research and action.5)Political engagement: Engagement of policy-makers to ensure political buy-in and subsequent action.SUNRAY has seven work packages: WP1 optimises communication and coordination within the Consortium. WP2 maps current nutrition research activities in sub-Saharan Africa, and examines the operating environment. WP3 analyses the views of stakeholders. WP4 examines the impact of environmental changes on nutrition. WP5 builds consensus on research priorities through workshops in three African regions. WP6 develops a strategic framework for future research in the form of a roadmap. WP7 disseminates project outputs. The SUNRAY Consortium has four Afri
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Digitally Adjustable Tooling for manufacturing of Aircraft panels using multi-point FORMing methodology' (DATAFORM) under Sixth Framework.

assistant: **Objectives**

The DATAFORM focuses on researching and developing digitally adjustable multi-point tooling for manufacturing of aircraft panels. The main advantageous features of DATAFORM are rapid, universal, and cost-effective with high flexibility compared with present hard fabrication tooling. It is the aim of DATAFORM to empower the tooling technology with a clear focus on industrial use for aeronautics, and to drive the rapid development of flexible tooling in manufacturing leading to new processes and immediate industrial exploitation. There are no such dieless forming tooling and jigless positioning tooling available on market. DATAFORM will play a key role in realising the full potential of flexible tooling by combining robotic control technology.The industrial and scientific breakthrough objectives of the project are:(1) Fundamental exploration of digitally adjustable multi-point tooling. This will lead to realise rapid dieless forming of skin panels and accurate jigless fabrication of panel structures in aviation.(2) Solution of the key technological problems of adjustable multi-point tooling. This will lead to develop an adjustable tooling composing punch matrices to replace the solid dies or hard tooling.(3) Development of the integrated CAD/CAE/CAT software and robotic close-loop control devices for the modular system. This will lead to an innovative analysis and optimisation process, the automatic control of punches and the quick adaptation to component design or engineering changes.(4) Development and implementation of digitally adjustable multi-point tooling in manufacturing of aircraft products.This will lead to reduce tooling costs by 60%, cut set-up time by up to 50% and decreasing tooling lead time, eliminate the need for tooling storage, and also increase tooling
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Advancing Sodium-ion Battery Cycle Life: Understanding Degradation in Hard Carbon Anodes' (EISNMR).

assistant: **Concept**

Na-ion battery (NIB) is the most promising technology among the next generation battery technologies. The main issue facing NIB is in their low cycle life. Limited cycle life of Na batteries results from degradation mechanisms occurring at both the cathode and the anode. While multiple cathode materials have been developed, the best-performing anode material remains hard carbon. Despite hard carbon's acceptable energy density, it suffers from inadequate cycle life. Significant efforts have been made to understand Na storage mechanisms in hard carbon. However, little effort has been devoted to understanding the degradation mechanisms and strategies to mitigate them. I propose research spanning multiple scales to evaluate the mechanisms causing degradation in hard carbon anodes and develop strategies to inhibit them, focusing on SEI and charge transfer mechanisms, and their influence by various operating parameters. This work will involve intensive mechanistic studies of Na-ion charge transfer and interfacial processes by conducting in-situ Electrochemical Impedance Spectroscopy (EIS) and Nuclear Magnetic Resonance Spectroscopy (NMR) measurements, which will identify and quantify the contributions of both Na-ion charge transfer and interface to hard carbon degradation. I will employ hard carbon symmetric cell configuration that allows for detailed analysis without the contribution from other electrodes. I will scale this mechanistic work with various parameters including electrolyte composition and temperature. The results will identify the primary contributors to the low cycle life of hard carbon anodes and bring strategies to extend their cycle life.


**Keywords:** Na-ion storage, Solid Electrolyte Interphase, Electrochemical Impedance Spectroscopy, Nuclear Magnetic Re
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Multicoloured ambipolar conducting polymers for single polymer optoelectronic devices'.

assistant: **Concept**

The project aims at conscious development of novel conjugated polymers featuring multielectrochromic properties that can find application in polymer electrochromic or electroluminescent devices. Our aim is to obtain new π – conjugated polymers, containing both electron-donor and electron-accepting units by first selecting their monomeric precursors using quantum chemistry tools. Following synthesis, electrochemical phenomena and changes in spectroscopic properties taking place during their redox charging, will be elucidated. These materials will combine interesting spectroelectrochemical properties with tuneable electronic conductivity and for this reason they can be applied in organic optoelectronic and in electrochromic devices. Detailed identification and understanding of their redox processes will allow developing ways to tailor their physicochemical properties. Our goal is to find, synthesise, characterise and device-test these oligomeric or polymeric materials which should be easily both “p” and “n” doped. Such materials will feature low electron band gap and hence should exhibit strong electromagnetic absorption in the visible region manifesting colour. Such materials should be applicable as both as hole and electron transporting layers, effectively simplifying the construction of electroluminescent devices. This is our key scientific goal. The second one would be to investigate the possibilities of tuning the energy of emitted light taking advantage of different redox states our envisioned polymers should exhibit. The complementary advantage of these materials should be the low threshold voltage for light electrogeneration, which would decrease the operating voltage of electroluminescent devices. Joint implementation of the proposed project will allow each partn
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Therapeutic role of different VEGF members on neuron and muscle degeneration'.

assistant: **Concept**

Recent evidence suggests that members of the VEGF family may be of therapeutic value for neurodegenerative disorders, such as amyotrophic lateral sclerosis (ALS). Indeed, VEGF administration significantly improved the clinical outcome of animal models of A LS.To further define the role of VEGF in motoneuron degeneration and in preparation of clinical trials, this project will investigate whether the expression of VEGF by the skeletal muscle might affect muscle atrophy and neuromuscular junction integrity in rodent models of ALS (SODG93A rats and mice).This hypothesis will be investigated by inter-crossing SODG93A with transgenic mice over-expressing or lacking VEGF in the skeletal muscle. Alternatively, in vivo VEGF gene transfer to skeletal muscle fibers will be obtained by using vectors based on the Adeno-Associated Virus (AAV).These models will represent a powerful tool to investigate whether muscle-derived VEGF can influence disease progression by maintaining muscle integrity or by inducing muscle regeneration and/or motor unit enlargement through axonal sprouting.In addition, further work will be focused on the role of a novel VEGF homologue, VEGF-B, and its receptor Flt-1, in motoneuron degeneration, based on the observation that ALS mice lacking VEGF-B display an aggravated phenotype.These mice will be therefore employed to determine whether VEGF-B exerts a neuroprotective support to motoneurons, atrophic effect on muscle fibers or a regulatory activity on glial cells.Finally, a possible therapeutic role of VEGF-B in ALS will be explored, by either directly injecting the recombinant protein into the brain ventricles, or by intramuscular injection of AAV-VEGF-B vectors.Collectively, these studies will generate insights with relevant implications to further optimiz
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Our Space our Future: making careers in the space industry an inspiring reality for all' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

The vision of Our Space Our Future (OurSpace) is a society that enables and empowers all students, regardless of gender, ethnicity, disability or socio-economic background, to consider a career related to space science as a relevant, attainable and exciting aspiration for their future. The space industry in Europe is strong and growing, offering innovative services and providing huge benefits across science, the economy, government and society . The space industry meets societal challenges, provides jobs and supports industrial growth and the standards of excellence within industry and research reinforces Europe as an autonomous, global leader in the sector.The OurSpace rationale is based on emphasis of these positive effects of STEM choices, not only for employment and the economy, but also the wider benefits of STEM and space science education for technical and intellectual progress, and on the wider skills and knowledge base of the public. Each of the consortium partners brings a unique breadth of experience and skills in space communication, stakeholder engagement, policy advice and direct experience of working with schools and families. The OurSpace project will design and run sustainable education and outreach activities, and take these out into communities, ensuring that underserved audiences are embraced and integrated into the project. OurSpace will engage over 60,000 people across the programme, with a longitudinal evaluation study that explores improved scientific literacy, interest and confidence in space science themes and assesses the impact on space-related and STEM choices and career aspirations of 5,000 directly-participating students across 4 delivery countries.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Novel sps processing of nanoscale ceramics for industrial and biomedical applications' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

The proposal is motivated by the availability of a novel ceramic sintering process (Spark Plasma Sintering) which enables densification of components in short times, purity, nanoscale grain size and potentially high strength. The process will be applied to pure oxide biomedical ceramics, to develop high strength femoral heads with fine surface finish and to metal cutting inserts with carbide or nitride dispersions in oxide matrices which have high toughness, wear resistance and low reactivity with important alloys. The objective is to develop an economic manufacturing route for oxide components which have large property increments over existing products, to facilitate EU competitiveness and international market penetration.-A suitable commercial grade of a-alumina was identified for use in the project studies. This, in conjunction with problems associated with fabricating suitable precursor materials within the project, meant that manpower effort could be switched from WP1 to WP3 in order to include rapid firing sintering in the work programme. The production of two types of whisker-reinforced materials was successfully fed into the processing programme. A colloidal precursor of zirconia toughened alumina (ZTA) was produced within the project and compared with commercially available powders.-PS, HP, sinterHIP and SPS have been carried out over a range of conditions and extensive analysis has been carried out on the samples produced. Cutting insert trials have been used to examine the most promising material / sintering combination. The SPS process demonstrated the expected benefits of nanoscale grain size, faster sintering times and increased mechanical properties. Results of the trails on the SPS processed cutting inserts proved very encouraging, especially with regard
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Role of intercellular adherens junction in the regulation of endothelial cell growth and apoptosis'.

assistant: **Concept**

Interendothelial adherents junctions play a crucial role in the development and maintenance of blood vessel integrity. Null mutation of the endothelial specific VE-adhering gene leads to impairment of vascular remodelling and endothelial survival, which is in part due to the loss of VEGF function as a survival factor in these instants. As it was shown that VE-adhering forms complexes with the VEGF receptor 2, in this project we will investigate the significance of VE-adhering in regulating VEGF function and which role beta-catena plays in this process. In adulation, since VE-adhering is an important determinant of contact inhibition of cell growth in the endothelium, the signalling processes at the basis of this activity will be studied. In order to address these questions endothelial cells cultured from VE adhering deficient mice will be used as a model for transfixion of various VE-adhering mutants in an endothelial background. Mutant proteins will be designed to alter either the binding or the detachment of beta-catena from VE-adhering. Furthermore the involvernent of the p120^ctn binding site and the significance of the extra cellular domain of VE-adhering will be investigated. In a second step, the beta-catena gene will be inactivated in endothelial cells specifically a Crew-Lox approach in vivo and the animal phenotype will be studied.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'CYPRUS 2026 EU CONFERENCE: ADVANCEMENT OF TREATMENTS FOR RARE DISEASES' (CY26-RARE) under Horizon Europe.

assistant: **Objectives**

Rare Diseases (RDs), often called orphan diseases, are a diverse group of disorders that collectively affect a significant number, approximately 30 million people in EU. The majority of rare diseases have a genetic origin and encompass a wide range of pathological conditions, many of which are chronic, debilitating and may shorten lifespan. Due to the rarity, complexity and the limited available knowledge, rare diseases pose significant challenges in terms of diagnosis, treatment and access to specialised care. Efforts to address rare diseases involve multidisciplinary collaboration, innovative research and policy initiatives aimed at improving outcomes for affected individuals. Moreover, the socioeconomic impact of rare diseases at the individual, health care and societal levels is significant, but in countries with centralised healthcare systems, the cost is spread out given the rarity of theses diseases.  The proposed high-level conference on the advancement of treatments for rare diseases (RD) within the EU, will be organised under during the Cyprus Presidency of the Council of the European Union, as one of the of the Presidency events. The conference aims to strengthen collaboration, foster innovation, and drive development in the field of rare diseases management. The conference will highlight the goal of making Europe “the global beacon for life sciences by 2030”, support concrete health benefits to rare diseases patients, through better prevention, diagnosis and treatment. This two-day event will focus on promoting excellence, innovation, collaboration and synergies on treatments for rare diseases.


**Keywords:** Rare Diseases, Advancement of Treatements, EU conference, CY presidency event