RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Modified Vacuum Rankine Cycle' (MOVARC) under Horizon 2020.

assistant: **Objectives**

MOVARC is a new thermodynamic cycle (inspired in both Rankine and Stirling cycles) coupled to an innovative transmission design working to generate energy from industrial waste-heat and other mid-level renewable eat sources such as biogas. The new thermodynamic cycle is patent protected and its innovation lies in the use of a closed-system vacuum chamber that increases the overall efficiency of the system. MOVARC does not require a turbine for energy generation, instead it relies on a transmission system and lineal work outputs. Mathematical models and experimental tests on the TRL6 prototype indicate an increase of efficiency of η=8-9% over competing solutions. In other words, MOVARC cycles transform mid & low-heat resources (industrial waste-heat or biogas) into energy at higher efficiency than current technologies including organic Rankine cycles, Kalina cycles, and Supercritical CO2 cycles.The lineal work generated by MOVARC is translated into rotational energy (via the patented transmission gear) and captured by a commercial electromagnetic generator to produce electricity. The transmission system that delivers the required linear-to-rotational exchange is also patented and was engineered for-purpose. The mechanical losses in the transmission are controlled using a novel bevel gear design with proven efficiencies in industry settings of η=98-99% for low RPM and near constant speed; both characteristics of MOVARC.We estimated that turnover related to MOVARC will reach €7.00 million by 2024, generating profits of €1.75M cumulatively. It is equally foreseen that the consortium we will grow in employees (9 new hires planned), specifically, in the manufacturing and business development and the research team at Cobertrans. Improved efficiencies (up to 9%) and lower €/KWh
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Quantum networks wired by multi-spin entanglement' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Entanglement is arguably the most defining and yet counterintuitive feature of quantum theory. The non-local nature of entanglement provides exciting opportunities for fundamentally new science and technologies. As a prime example, recent theoretical work has uncovered the unique potential of a future quantum network: a network of nodes consisting of multiple well-controlled quantum particles “wired” by quantum entanglement. Such a network would enable distributed quantum computing and simulation, secure communication, enhanced metrology and new fundamental studies of nature. Although recent pioneering advances in quantum control have made quantum networks a realistic prospect, remote entanglement has so far been limited to two long-lived spins in trapped ions, atoms, quantum dots and diamond defect centers.My QNETWORK project will realize a multi-node entanglement-based quantum network. The network will have fully controlled multi-spin nodes at individual diamond defects connected by single-photon links. Using this quantum network I will demonstrate supremacy of a quantum repeater node over direct photon transmission, generate multi-spin entanglement and study its decoherence, realize quantum teleportation across multiple nodes and finally exploit the network for new scientific experiments ranging from super-activation of entanglement distillation to foundational tests to quantum secret sharing.To achieve these ambitious goals, this proposal will capitalize on two recent breakthroughs with single electron spins trapped in diamond defects in my group. First, we have entangled electron spins on different chips (most recently over a distance >1km). Second, we have achieved full control over a handful of nuclear spins near one such electron, providing the required quantum
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'CIRSEAU. BUILDING A WATER-SMART ECONOMY AND SOCIETY' (CIRSEAU).

assistant: **Innovation**

To accelerate the transition to a circular economy, the European Commission (EC) promoted alternative water resources in the Horizon 2020 Framework. To increase water use efficiency and reuse, the call CE-SC5-04-2019 funded five different projects (B-WaterSmart, WIDER UPTAKE, REWAISE, ULTIMATE and WATER-MINING). These five projects run from 2020 to 2025, with a total budget of 84 M€, and EU contribution of 71.5 M€, and share the objectives of identifying alternative water sources, reducing water consumption, increasing use efficiency, recovering valuable materials from water, producing carbon-free water cycles, and increase resilience to climate change. To leverage the resources from EC wisely, the five coordinators decided to share common knowledge, promoting synergies and avoiding reinventing the wheel. This resulted in the creation of a cluster called CIRSEAU, to connect 143 partners in more than 20 countries, reaching almost all members stated of the European Union (EU), in addition to countries like India or Ghana outside the EU. Building on the alliance formed to foster cross-promotion, communication alignment, and impactful outreach for the five projects funded under the EU research call on building a water-smart economy and society (CE-SC5-04-2019). To reach the outcomes of this CSA, additional experts and partners have been asked to complement experience and competence of CIRSEAU. This consortium brings together 10 partners from 6 countries (BE, DE, ES, GR, NL and NO) to provide multidisciplinary expertise and trans-nationality required to foster cross-promotion, communication alignment, and allow impactful outreach to public authorities, policy makers, and standardization bodies. The main objective of the CSA is to build a collaborative ecosystem that generate
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'How does cross-talk between drug transporters and drug metabolism affect drug disposition' (2002-2006) targeting Sixth Framework.

assistant: **Abstract**

The availability of in vitro models that mimic Absorption, Distribution, Metabolism, and Excretion (ADME) of new drugs in human combined with a thorough mechanistic knowledge about the processes that determine ADME, would greatly benefit the development of novel medicines. In many cases the hepatic uptake of drugs is mediated by Organic Anion Uptake Transporters (OATPs). Intracellularly, drugs are metabolized in two steps, termed phase I and phase II of drug metabolism which are catalysed by enzymes such as cytochromes P450 andUDP glucuronosyl- or suIfo-transferases respectively. The resulting conjugates are eliminated into the bile by drug efflux pumps.It is our objective to investigate the interaction of these various systems in vitro in recombinant cell l ines. The systems to be studied include human drug metabolizing enzymes (eg. sulfo-transferases and UDP-glucuronosyltransferases) and drug carriers (eg. Organic Anion Uptake Transporters (OATPs) and Multidrug Resistance Related Protein (MRP) efflux pumps). The project would be realized through a partnership between the Development Centre of Eli Lilly in Belgium and the University of Dundee. An experienced researcher would be hired by Lilly and would work for two years at Dundee where he would apply genomics for the characterization of cell line enzymes and molecular biology for the expression of human enzymes and carriers in those cell lines. During this period he would also spend some time at Lilly for the validation of the systems using specific probe subs trates. The researcher would benefit from the knowledge in genomics, proteomics, cell biology at Dundee and would transfer this knowledge at Lilly where he/she would return after two years, to implement therethese in vitro systems to screen new drugs and b etter
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'REfactoring Parallel Heterogeneous Resource-Aware Applications  - a Software Engineering Approach'.

assistant: **Concept**

The RePhrase project directly meets the challenge of ICT-09-2014, by studying the critically important issue of improving software development practice for parallel data-intensive applications. Data-intensive applications are among the most important and commonly encountered kinds of industrial application, and are increasingly important withthe emergence of ""big data"" problems. Emerging heterogeneous parallel architectures form ideal platforms to exploit themassive-scale inherent parallelism that is usually implicit in such applications, but which is often difficult to extract in practice. Solving this problem will bring major economic benefits to the software industry.To address this challenge, RePhrase brings together a team of leading industrial and academic researchers, software engineers, systems developers, parallelism experts and domain experts from large companies, SMEs and leading universities. It aims to develop a novel software engineering methodology for developing complex, large-scale parallel data-intensive applications, supported by a very high-level programming model. We will exploit advanced pattern-based programming, refactoring, testing, debugging, verification and adaptive-scheduling technologies to build an interoperable tool-chain supporting our methodology, based on but significantly extending existing industrial and research tools. These tools will significantly ease, and even automate, all phases of typical software development, from design and implementation to long-term maintenance and software evolution. The generality of our approach will be ensured by targeting C++ and the most popular low-level parallel programming models, such as the C++11/14/17 standards, pthreads, OpenMP, Intel TBB, OpenCL and CUDA.  We will demonstrate our approach
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Building up the Milky Way Halo in the era of multiple stellar populations' (Global-assembly), addressing dissemination and exploitation.

assistant: **Impact**

In the Galactic halo the footprints of early hierarchical processes can be easily recognized, with some still observable events, such as the merging between the Sagittarius galaxy and the Milky Way. With the discovery of multiple stellar populations in globular clusters (GCs), we are entering a new era in the study of the halo. We now know that typical Milky Way GCs host different stellar populations, with some of them resembling the Sagittarius nuclear GC M54, and Omega Centauri, proposed to be the survived nucleus of a dwarf galaxy.Recent photometric effort has revealed that the ""populations pattern"" in GCs is even more complex than previously believed, with the observation of minor populations for which we still do not have information of their nature, i.e. of their chemical composition.Many aspects about the nature of GCs are matter of a lively debate: Which is the origin of GCs? Could have some of them been former nuclei of dwarf galaxies? Which is their contribution to the halo? To answer these questions we lack a systematic and comprehensive analysis of the nature of “all” the stellar populations observed in GCs.Recently we have photometrically detected multiple stellar populations in the young GCs of the Magellanic Clouds (age of few hundreds Myrs). Are these the young counterpart of the old Milky Way GCs (10<age<13 Gyrs)? If yes, we have the unique opportunity to analyse, in the local Universe, an obscure phenomenon occurred at high redshift. To address this issue a chemical characterisation of the stellar populations observed in these young GCs is needed.Thus, the new revolutionary photometric discoveries impose a major effort in the chemical/kinematical analysis of this phenomenon. With this project, I propose to exploit my expertise in spectroscopy in clos
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Laser-assisted sYnthesis of Magnetically mOtile plasmonic chiral Nanocatalysts' (LYMON), addressing dissemination and exploitation.

assistant: **Impact**

Catalysis holds immense significance in chemical manufacturing, being a key player in developing sustainable industrial processes with limited energy & resource consumption. In pharmaceutical industry, catalysis is crucial for enabling mass production of affordable life-saving drugs. However, developing efficient catalysts for this sector poses a formidable challenge due to the inherent asymmetry of many biological processes. This is particularly critical in producing anticancer drugs because their synthesis relies on intermediates or reactions whose asymmetric nature, known as chirality, withholds their massive production, limiting equal global access to best health treatments.An up-and-coming solution to address this dilemma is resorting to chiral plasmonic nanoparticles (NPs), as their outstanding optical rotation activity makes them well-suited for applications like polarization-sensitive photocatalysis, especially in the context of anticancer drug development. However, unleashing its full potential hinges on imbuing these chiral NPs with unusual properties like magnetism, allowing safe removal from products & recyclability without generating chemical waste. To date, creating a plasmonic structure that seamlessly integrates chirality with magnetic motility remains largely underexplored.The LYMON project addresses this conundrum by expanding the repertoire of chiral nanocatalyst construction methods through a groundbreaking laser-based pathway. This innovative approach, supported both experimentally & theoretically, promises to bring a new generation of highly specific magnetic chiroplasmonic nanocatalysts characterized by their ability to be reused multiple times. All of this permiting reducing wasteful side reactions & improving control over pharmaceutical producti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Molecular characterisation and epidemiology of encephalomyocarditis virus : a model for emerging diseases' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

Encephalomyocarditis virus (EMCV), a member of the genus Cardiovirus in the family Picornaviridae, is regarded as a virus of rodents but can on occasion cause disease in a wide variety of animals including domesticated pigs. EMCV may either cause sudden death in piglets or reproductive failure in sows. These disease syndromes were first observed in Europe in 1986 and have increased in frequency since that time. The transmission and spread of this emerging European disease is poorly understood both in wildlife and domesticated species. In this study we will investigate three areas, I) the epidemiology of EMCV disease; ii) virus strain virulence; and iii) diagnosis of EMCV infections. Epidemiology: Firstly the epidemiology and economic implications of EMCV infection in pigs will be studied by investigating the mode and kinetics o virus spread on an infected farm. The prevalence and spread of EMCV throughout Europe will be studied by the collection and genetic analysis of viruses from both wildlife (rodents etc.) And pigs and by surveying these populations for antibodies to EMCV. The route of EMCV transmission will be studied experimentally. Host (genetic) and environmental factors (such as stress) which may influence the outcome of an outbreak will be studied. We will determine reliable parameters of immune protection. All the above data will be used to create an epidemiologic and economic computer model for EMCV disease which may also be used for emergmg diseases in general. Virus strain virulence: We will investigate the basis for the variable virulence of EMCV strains in pigs by characterisation of viruses at the genome level. Initially genome areas known to be involved in the virulence of other Picornaviruses (S' UTR, poly-C tract, VP1, 3' UTR) will be studied in a nu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'INtentify future Transport rEsearch NeeDs' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

INTEND will deliver an elaborated study of the research needs and priorities in the transport sector utilising a systematic data collection method. Megatrends that will be affecting the future transport system will be identified using literature review. To ensure validity of the results,  the Analytical Network Process will be used to weight the megatrends and derive reliable outcomes on the most predominant trends. Finally, INTEND will develop a transport agenda that would pave the way to an innovative and competitive European Transport sector. The project is driven by three main objectives:-Define the transport research landscape-Define the Megatrends and their impact on research needs-Identify the main transport research needs and prioritiesTo enable a wide range of  stakeholders to gain access to the results, INTEND will develop an online platform, the INTEND Synopsis tool that will constitute a dynamic knowledge base repository on the major developments in the transport sector. This will provide a visualisation of the INTEND's main outcomes. The basis for the platform will be Transport Synopsis Tool which is already developed under the project RACE2050  coordinated by TUB. The repository will be updated and integrated into the INTEND website to provide a comprehensive picture of all forward looking studies focusing on technological developments, megatrends and policies. INTEND consortium represents a unique group of highly competent and experienced research teams, composed specifically for the purpose of the project. Their selection was based on the following criteria:1.Personnel and infrastructure capacity to adequately implement the project2.Established international relationships 3.Team working experience
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Duo: A minimally invasive device to treat all patients with tricuspid valve disease' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Heart failure is the leading cause of death, affecting 15 million patients across Europe and the US. In patients with heart failure, the right heart expands, resulting in the tricuspid valve not closing properly and blood leaking backwards. This is called tricuspid regurgitation. The tricuspid valve has remained largely untreated due to unique functional and anatomical challenges.  Currently less than 1% of patients are surgically treated due to the fact that open-heart surgery is still the only treatment option and is very risky. As a result, these patients face worsening quality of life with 60% of patients not surviving past 3 years.The Duo project aims to enable the commercialisation of a minimally invasive device that restores the function of the tricuspid valve in a safe and effective manner for all patients with TR. An innovative adjustable anchor holds the device in position between the tricuspid valve leaflets, anchored against the venous wall, where it does not touch the fragile cardiac tissue.This multi-disciplinary consortium of innovative SME’s is uniquely positioned to accelerate bringing this disruptive technology to market. CroiValve, the consortium coordinator, was founded specifically to develop and commercialise a minimally invasive tricuspid treatment. ICS Medical is an expert in the design, development and manufacturing of complex catheter solutions. Syntactx is a full-service CRO that understands how to deliver efficient and good quality clinical data. 3D LaserTec is an innovation driven centre for laser cut parts. With Fast Track to Innovation funding, the consortium will finalise the development of the Duo-TF device and develop US clinical evidence demonstrating the clinical benefits of Duo to the patient. This will position Duo as the gold stand