RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Using a novel animal model of the dopaminergic dysfunction of schizophrenia to trial an innovative treatment approach' in the context of a Horizon 2020 call.

assistant: **Objectives**

Treatments for schizophrenia are inadequate, and intervening prior to disease onset is a novel approach to improve patient outcomes. Clinical studies using positron emission tomography (PET) have revealed that patients with chronic schizophrenia consistently show an increase in dopamine synthesis capacity in the striatum. This dysfunction is also evident in people at-risk of developing schizophrenia, specifically in those who are later diagnosed with this disorder. Normalizing this increase in pre-synaptic dopamine therefore reflects an extremely promising target for new treatments of schizophrenia. I developed a novel animal model of schizophrenia – Enhanced Dopamine in Prodromal Schizophrenia (EDiPS) – which replicates the pre-synaptic dopaminergic dysfunction seen so robustly in patients. In this project, I propose to firstly use state-of-art preclinical PET to examine pre-synaptic dopamine in EDiPS animals. This will confirm its translatability to the findings in the clinical population. Through a secondment, I will assess other key aspects of dopamine neurotransmission in these animals, focussing on the source of dopaminergic innervation to the striatum – the midbrain. As a complementary objective, I will assess any difference between male and female EDiPS animals for each of these outcomes. This is especially relevant to schizophrenia, which is a sexually dimorphic disorder. The second objective of this fellowship is to trial a novel approach to normalise the increase in pre-synaptic dopamine in EDiPS animals, through a Trace Amino Acid Receptor 1 (TAAR1) agonist. I will trial the TAAR1 agonist both acutely in adult EDiPS animals, and when given chronically during development, to simulate an intervention in the at-risk population. This will be the first study to e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'An innovative dual action (antimicrobial & immunomodulator) product for the aquaculture feed additives market' (AQUAGARLIC) targeting Horizon 2020.

assistant: **Abstract**

Domca is a Spanish company with more than 40 years of experience offering turnkey solutions for the agri-food and animal feeding sector. One of our key points is the development and production of products for animal nutrition, extracted from natural products and manufactured under strict standards. A sample of our experience, is the line of animal nutrition products, which based on extracts of Aliaceae, nourish and improve the performance and growth of terrestrial animals. Diseases on aquacultured fish are a clear indicator of the presence of pathogens (normally microbes &/or parasites). These pathogens can cause health problems to humans when eating the infected fish. Beside this, loss of yield in aquaculture production can rise up to 50% due to this situation. The objective of this Phase I project, AQUAgarlic, is to create a feasibility study for the launching of Domca’s new product in the aquaculture market, with the first dual action (antimicrobial and immunomodulator) feed additive for aquaculture industry based on organosulfur natural active ingredients, with zero residues, effective and environmentally friendly, expanding our sales portfolio while we enter a market of € 1.05 billion (CAGR of 3.2%). This product would be a game changer, as most related products (synthetic medicines) are not environmentally friendly and are targeted to only one specific threat (microbe or parasite). To ensure a smooth take-off in the market, we have a team specialized in controlling the distribution operations in Europe, Africa and Asia, as well as subsidiary companies in Chile and Argentina, which will be in charge of market introduction in Latam. Upon completion of this project, Domca will submit a Horizon 2020 SME-Phase II proposal to the industrialization and market launching.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Screening and metabolic engineering of microbes for the production of lignans' (1998-2002), addressing dissemination and exploitation.

assistant: **Impact**

Bacteria and fungi will be screened for their ability of lignin biosynthetic reactions. Metabolic engineering of suitable fungal hosts will be performed to construct lignin producing microbial strain. The work is of value for testing novel production hosts for medically and nutraceutically important lingams.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Finding the Origin of the Slow Solar Wind' (2014-2020).

assistant: **Innovation**

The origins and release mechanisms of stellar winds are long-lasting open challenges in astrophysics. Stellar winds play a fundamental role in the long-term evolution of stars and the habitability of their orbiting planets.  In the solar case, the wind is observed in at least two states, fast and slow winds, that differ in their bulk properties and composition, pointing to different coronal origins. A theoretical explanation for the slow wind must explain both its variable bulk properties and its peculiar composition. This includes the measured high charge states of minor ions, the abundance variation of Helium during the solar cycle and the high abundance of elements with low first ionisation potential (so called FIP effect) reaching four times the photospheric abundance. SLOW_SOURCE is a comprehensive research project that will use current and upcoming observations as well as completely novel models of the solar atmosphere to determine the origin of the slow wind. We will develop plasma transport models coupling major and all known important minor constituents along realistic coronal magnetic field lines. This model will be the first of its kind producing modelled observations (spectroscopy, imagery) and expected in situ signatures directly from the modelled minor constituents.  Combined with data from space and ground-based observatories, our new multi-species, multi-temperature 3-dimensional modelling of coronal plasma will provide new ways to infer the properties of stellar winds and tools to study the fundamental transport and heating processes of stellar plasmas. Determining the enigmatic release mechanism(s) of the slow solar wind constitutes a key objective of the upcoming Parker Solar Probe mission that will obtain radically new observations right from the sta
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Innovative Enterprise Vienna 2018' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Objective of the project is a 2 full day international conference (21-22/11/2018), including a restricted Pre-conference Dinner in the evening prior to the conference The conference will focus on financial instruments for highly innovative enterprises. The event is rooted in the Work Programm 2018-2020 of ‚Access to Risk Finance/Horizon 2020‘ and is listed as an official event of the Austrian EU Council Presidency in the second semester of 2018. The conference ‚Innovative Enterprise Vienna 2018‘ will help companies and organisations engaged in research and innovation (R&I) to better understand how to gain access to financial capital - in the form of loans, guarantees, counter-guarantees and hybrid, mezzanine and equity finance - which is necessary for company/entity to fully exploit its innovative capacity and - basically - turn it into market success. The pallet of InnovFin instruments are of central importance for the event. The conference will take place at a very decisive moment of time with respect to the planning process of the forthcoming financial period. In this context, a prospective view on the plans for the ‚European Innovation Council/EIC‘ of Horizon Europe will be a most important element of the conference. Similarly, also prospects on Invest EU (with respect to R&I-relevant activities) will also be dealt with. In addition to a full-2-day event for ca. 500 participants with series of keynotes and consecutive panel sessions, the event will also demonstrate equity finance in practice - by integrating 2 ‚investment pitching‘ formats for highly innovative companies. These pitching formats are foreseen for around 120 persons.  Obviously, a most professional, smooth, hospitable, thematically well composed and technically well equipped event with integrative and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'New accurate batch anodising technology' (1998-2002), addressing dissemination and exploitation.

assistant: **Impact**

Alucol as a SME's involved in batch anodizing of aluminum products, e.g. in architectural applications, is under pressure from legally enforced reductions in energy consumption, competitive coating techniques, like powder coating, and market demands for reproducible and sustainable products. Using existing anodizing technology a distribution of oxide layer thickness and quality over a batch of products is obtained, resulting in longer process times than necessary and insufficient reproducibility of colored oxide layers. This forces us and other European SME's to seek new ways to improve the energy efficiency and accuracy of current batch anodizing technology and thereby safeguarding and widening our market. It is the objective of this proposal to improve the process of industrial batch anodizing with respect to the energy efficiency and the quality of the anodic layer by the introduction of new process technology, designed on the base of computer simulations and accurate electrochemical data. The hence obtained precise prediction and control of process will lead the way to an improvement of the energy efficiency with 25% by a reduction in process time.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'FeDerated nEtwork of pLatforms for Passenger and freigHt Intermodality'.

assistant: **Innovation**

Growing challenges are identified during the last years in both passenger and freight mobility, such as urbanization trends, the increasing complexity of stakeholder scene, e-commerce, rising fragmentation of freight transport. Despite the various technical challenges and shortcomings, current governance and regulatory systems have proven so far inadequate, dealing with the passengers and freight transport systems as independent -and thus disconnected- sectors while integration between passenger and freight transport has been a subject of debate in the transport community over the last years  with a peak coming after the recent Covid19 crisis. DELPHI focuses on the strategic dimension of integrating passenger and freight transport in a single system aiming to deliver the enablers -both on technical and governance/regulatory level, towards a federated network of platforms for multimodal passenger and freight transport, capable of sharing in a seamless and secure manner, cross-sectoral, multi-modal passenger and freight transport data, as well as traffic management systems information. Moreover, DELPHI will utilise novel and ultra-efficient methodologies for traffic monitoring such as UAS-powered monitoring, multi-/inter-modal optimisation, AI/ML-powered algorithms and frameworks, and will exploit diverse modes for hybrid passenger and freight transport in different ecosystem types. To achieve its maximum potential, utmost interoperability and best optimisation results, DELPHI’s digital framework and transversal tools will be validated in the context of 4 pilots with complementary requirements and features.


**Keywords:** governance, federated network of platforms, data federation, inter-modal optimisation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'A cultural history of comparative art practices and receptions in Cold War Europe (1945-1991)' in the context of a Horizon 2020 call.

assistant: **Objectives**

Cold War studies tend to emphasize dual narratives, mostly investigated as actions that are dictated from above by State policies or as cultural relations in an international context. Starting from my previous studies on bilateral art relations in the second half of 20th century, the project is intended as a comparative survey within a polycentric and inclusive European focus area, including the two German republics, Yugoslavia, the Soviet Union and Italy. The main study cases will be provided by multilateral art encounters and the involved locations and actors, analysed as individual and collective art practices. Unique Cold War art archives and collections at the Getty Research Institute and at the Wende Museum in Los Angeles will provide key resources. In order to assess the impact of the art practices on culture and society, I intend to investigate both their critical reception in the professional art world and their popular response through the commentaries left by exhibition visitors. A crucial question is whether the European dimension has ever been considered as a common ground - be it of political, social, artistic or speculative nature - for multilateral art practices within the divided continent. Particular attention will be paid to unmet expectations and missed connections among the interested art communities. By including current Member and Associate States and Third Countries, the research is meant to contribute to inter-European comprehension and integration, as an essential premise in order to “inform the reflection about present problems and help to find solutions for shaping Europe's future”, as stated in the Work programme 2016-2017 of Horizon 2020. The project is conceived as a multidisciplinary research which, through training and inter-sectoral mob
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Elucidating Mechanisms of Bladder Cancer Metastasis'.

assistant: **Objectives**

Bladder cancer is the ninth most afflicted cancer in the world which affects people in both developing and developed countries; and European nations have some of the highest incidences. Poor prognosis and mortality rate is very often linked to formation of secondary tumour sites in these patients. In advanced stages of this cancer, cells strive to invade nearby tissues in a process called metastasis. More often than not, patients suffer more due to metastasis of cancer than through the original tumour. In this project, I will investigate the mechanisms which lead to bladder cancer metastasis; identify key components in the pathways and also test out specific inhibitors to mitigate the growth and/or metastasis. Having an acute knowledge of ‘how and which’ pathway(s) promote metastasis in bladder cancer should provide us with information so that specific components can be targeted. Moreover, the proposed study also focuses on developing state-of-the-art biomarker strategies to identify patient populations which will best benefit from our inhibitor therapies. This project will enable the translation of experimental results obtained from lab bench to understanding how some patients will best benefit from certain inhibitor therapies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Survey on the research landscape in the Associated Candidate Countries formonitoring and promoting Good Quality Meat production - the whole food-chainfrom farm to fork of Poultry and Pork Meat' under Sixth Framework.

assistant: **Concept**

The proposal is Specific Support Action to promote the co-operation between European and Associated Candidate Countries on research activities in the specific field of quality and safety of meat. The proposers, through the development of this project proposal, will support on one side the European Commission in creating the European Research Area (ERA) which includes as well the Member Countries as the Associated Candidate Countries and on the other side the actors in the research field from associated candidate countries in participating in FP6 projects. The proposal focus its attention on a specific topic which has been selected on the basis of an overall European strong social need and of the keen interest of researchers in associated countries in the sector. The topic of the proposal is the quality of poultry and pork meat, it involves all the actors in the entire food chain of poultry and pork meat. The ambitious aim of this proposal will be achieved through various activities carried out by all the partners involved in the project, which are detailed in the proposal. The activities and the relative objectives of the proposal are: 1. Create a database of researchers and research centers working in the specific field in the Candidate Countries, 2. Implement a virtual on-line partner search mechanism with the supporting data base, 3. Organize a series of conferences on meat safety and quality combined with FP6 Info Days and promotion of research potential in Candidate Countries, 4. Organize a Brokerage event International Brokerage Event Meat Safety" to: o Present selected best research centers, o provide opportunities for meetings, discussions and presenting project ideas o diffuse the results of projects financed in past Framework Programmes on the identified topic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Nutritional biomarkers to advance understanding of association between diet and type 2 diabetes' (NUTBIO-DIAB) targeting Horizon 2020.

assistant: **Abstract**

Objectives: There is an unabated rise in the burden of type 2 diabetes (T2D) with associated premature morbidity, mortality and cost to individuals and society. There is an urgent need to identify modifiable factors that can prevent T2D. This Fellowship aims to use objectively measured nutritional biomarkers to improve the precision of dietary assessment for investigating the association between dietary factors and T2D risk. The use of biomarkers opens the possibility to investigate gene/diet interactions, which can lay the foundation for future stratified or personalised nutrition, and to address causality of associations using genetic-based approaches.Method: Measurement of plasma vitamin C, six carotenoids and 25-hydroxyvitamin D is now complete in the EPIC-InterAct study across 26 centres within 8 European countries in the world’s largest study of T2D incidence with 12,403 new-onset T2D cases, and a random sub-cohort of 16,835 individuals. We will examine the distribution and determinants of these nutritional biomarkers within European populations and investigate the association between biomarkers and T2D, and biomarker-gene interaction on T2D. Combining these data with other studies, we will use Mendelian randomisation to examine potential causal association of biomarkers with T2D.Relevance: Diet and nutrition are crucial for the prevention of non-communicable disease including T2D, but measurement error in self-report dietary assessment has posed a major challenge in identifying specific dietary components that elevate or mitigate disease risk. The systematic use of nutritional biomarkers on an unprecedented scale opens up an important new frontier to advance diet/health research. Specifically, this proposal will clarify the distribution and determinants of import