RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Validated Surge Model'.

assistant: **Innovation**

Filton Systems Engineering (FSE) intends to establish methodologies, which have been verified using test data, to provide validated accurate surge pressure predictions within aircraft fuel systems.  This would replace physical Aerospace Test Rigs with a virtual test rig to reduce development cost and lead-time by improving the robustness/integrity of surge/ two phase flow fluid modelling.  This allows aerospace companies to optimise architecture early in the design phase minimising installation and structural weight, increasing aircraft efficiency, thereby lowering operating cost and also reducing carbon footprint.Commercial realisation of the programme is through the sale of services/methodologies to aerospace customers and also potentially through the sale of validation test data to software houses to improve their marketing position relative to claims for predicting surge pressures; and the expansion of methodologies to cover fluid applications in other industries.FSE is uniquely positioned to succeed within this task due to existing surge analysis, test management and rig specification capabilities which will also protect further work that develop from this programme of work.The feasibility study undertaken under Phase 1 will comprise:1.IP investigationa.Current IP for similar methodologiesb.Use of IP to protect methodologiesc.Use of copyright to protect data2.Potential commercial arrangements with final customersa.Requirementsb.Use of data, services & methodologies 3.Potential commercial arrangements with software housea.Support for commercial codeb.Use of validation test data4.Statement of Work for Phase 2 (inc. plan & budget)5.Top level test facility requirements6.Top level test requirements7.Produce Comprehensive Feasibility ReportIf Phase 1 is successful, furth
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Fas Receptor Mediates seizure induced neuronal death and Epileptogenesis' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Epilepsy is an enormous health problem in the E.U., affecting 1-3% of the population. Improved treatment of epilepsy and prolonged single seizures (status epilepticus) would be achieved by targeting the causes of epilepsy and the consequences of seizures. Termed FARMINDE (FAs Receptor Mediates seizure Induced Neuronal Death and Epileptogenesis) this proposal uses a novel transgenic mouse model to investigate a novel cell-signalling pathway in seizure-damaged and epileptic brain. The project will examine how this death receptor influences neuronal loss after seizures and epileptogenesis.This Marie Curie International Reintegration Grants application is from a researcher who has been an NIH-funded investigator in the USA for the past five years. Work during this time using both in-house developed seizure models and human material challenges prevailing views on the molecular determinants of seizure-induced neuronal death and epilepsy, and offers new directions for treatment. The Researcher has a proven record of translational research with high-impact papers co-authored with clinicians on the subject of epileptic brain injury; skills and training in a bench-to-bedside approach that is a deficit in European research and which can now be brought to the Royal College of Surgeons in Ireland (RCSI, Host).The RCSI has evolved as the leading Irish institution in state-of-the-art proteomics, resources incorporated into this proposal. RCSI has likewise built a critical mass of experts in the study of the pathogenesis of brain injury, setting the stage for a world-leading team at RCSI in this field. Thus the Researcher can develop their programme of translational epilepsy research, learn new skills through RCSI technology strengths and provide training in bench-to-bedside approaches
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Nano-scale Development of Plasmonic Amplifiers Based on 2D Materials' to be submitted under Horizon Europe.

assistant: **Abstract**

The library of 2D materials is growing at a rapid rate driven by the potential extraordinary electronic applications that they can offer.In parallel, terahertz (THz) technologies has continued to draw a great interest due to the many applications that it can have aprofound impact in but has continuously been hindered due to the low power and wide scale applicability of current THz sourcetechnologies. THz surface plasmonics is coming in to the forefront as an area which can bridge these two emerging technologies andallow the necessary breakthrough that is needed in the so called THz source gap region of 0.5 – 3 THz. In this project the goal is todevelop architectures which can efficiently amplify THz waves based on surface plasmons in 2D materials. The fundamental attributesthat underline this approach resides in the interaction between THz radiation and electrically driven surface plasmons which providesamplification through an exchange of energy and momentum limited only by the properties of the gain medium. Thus the limits ofthe amplification are governed by limits to the electrical excitation of surface plasmons and how well these surface plasmons coupleto the THz radiation. By utilizing novel 2D materials with extraordinary electrical properties based on Transition MetalDichalcogenides (TMDs) and Transition Metal Monochalcogenides (TMMs) as well as traditional carbon based materials such asgraphene we plan to stretch these limits and achieve ground breaking results in terms of amplification and gain by incorporating thedeveloped amplifiers into existing state-of-the-art Silicon – Germanium hetero junction bipolar(HBT) based THz arrays. In the consortium led by THALES, leading experts from advanced research institutes, SMEs and universitieswhich specialize in growth
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'LINEAR INFRASTRUCTURE EFFICIENCY IMPROVEMENT BY AUTOMATED LEARNING AND OPTIMISED PREDICTIVE MAINTENANCE TECHNIQUES' (INFRALERT) targeting Horizon 2020.

assistant: **Abstract**

INFRALERT aims to develop an expert-based information system to support and automate linear asset infrastructure management from measurement to maintenance. This enfolds the collection, storage and analysis of inspection data, the deduction of interventions to keep the performance of the network in optimal condition, and the optimal planning of maintenance interventions. It will also assess new construction strategic decisions.The condition of the land transport infrastructure has a big societal and economic relevance, since constraints result in disruptions of service. The demand for surface transport will significantly increase in the next years. Given budget restrictions, a substantial enlargement of the road/rail network in the next decades is doubtful. Besides, the aging infrastructure will require more maintenance interventions which infer normal traffic operation. Therefore, the only way to increase infrastructure capacity for the increased transportation demand is to optimise the performance of the existing infrastructure. This issue is addressed by INFRALERT. INFRALERT will develop and deploy solutions that enhance the infrastructure performance and adapt its capacity to growing needs by: (i) ensuring the operability under traffic disruptions; (ii) keeping and increasing the availability by optimising operational maintenance interventions and assessing strategic long-term decisions on new construction; and (iii) ensuring service reliability and safety by minimising incidences and failures.INFRALERT will be directly applicable by Rail and Road Infrastructure Managers in the field of Intelligent Maintenance and long term strategic planning. Two real pilots (for roads and rail transport systems) will be used to validate and demonstrate the results of the research
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'STRUCTURE PRESERVING APPROXIMATIONS FOR ROBUST COMPUTATION OF CONSERVATION LAWS AND RELATED EQUATIONS' in the context of a Seventh Framework call.

assistant: **Objectives**

Many interesting systems in physics and engineering are mathematically modeled by first-order non-linear hyperbolic partial differential equations termed as systems of conservation laws. Examples include the Euler equations of aerodynamics, the shallow water equations of oceanography, multi-phase flows in a porous medium (used in the oil industry), equations of non-linear elasticity and the MHD equations of plasma physics. Numerical methods are the key tools to study these equations and to simulate interesting phenomena such as shock waves.Despite the intense development of numerical methods for the past three decades and great success in applying these methods to large scale complex physical and engineering simulations, the massive increase in computational power in recent years has exposed the inability of state of the art schemes to simulate very large, multiscale, multiphysics three dimensional problems on complex geometries. In particular, problems with strong shocks that depend explicitly on underlying small scale effects, involve geometric constraints like vorticity and require uncertain inputs such as random initial data and source terms, are beyond the range of existing methods.The main goal of this project will be to design space-time adaptive \emph{structure preserving} arbitrarily high-order finite volume and discontinuous Galerkin schemes that incorporate correct small scale information and provide for efficient uncertainty quantification. These schemes will tackle emerging grand challenges and dramatically increase the range and scope of numerical simulations for systems modeled by hyperbolic PDEs. Moreover, the schemes will be implemented to ensure optimal performance on emerging massively parallel hardware architecture. The resulting publicly available c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Investigating the electron uptake mechanisms of bacteria on bio-cathodes for microbial electrosynthesis' (BioCat), addressing dissemination and exploitation.

assistant: **Impact**

The project „BioCat“ investigates electron uptake mechanisms of electroactive bacteria catalyzing reduction processes on biocathodes at the protein membrane level. Thus, the project will significantly contribute to the basic understanding and optimization ofmicrobial electrosynthesis.The driving force for the increasing interest in microbial electrosynthesis is the intriguing capacity of this technology toproduce high value chemicals from carbon dioxide and electricity. This conversion addresses carbon capture and storageissues of renewable power sources and will contribute to a carbon neutral economy and society.The project will be conducted at the Inorganic Biochemistry and NMR group (IBN) of the ITQB NOVA in Lisbon with asecondment at the University of Tübingen at the Laboratory of Prof.Dr. Lars Angenent.BioCat is divided into three main objectives. First of all a basic understanding of the role of c-type cytochromes and theindirect or direct nature of the electron transfer will be investigated with Shewanella oneidensis. Subsequently Sporomusaovata and its membrane proteins carrying out electron transfer are studied, while the production of acetate from CO2 ismonitored. Both will be analyzed as a function of operating parameters (electrode potential and pH). To round up the project, an optimized continuous run prototype reactor will be operated and characterized.The project will enable the researcher Joana Madjarov to get trained in the whole chain of basic to applied research. Themain focus lies in the fundamental biochemical research, but the project directly links the findings to application relevant acetate production yields and efficiency.


**Keywords:** Bioelectrochemistry, Microbial electrosynthesis, Bio-cathode, acetate, NMR, Electron transfer, mechanisms,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'GraCerLit – Development of Functionally Graded Ceramics by Lithography-based Ceramic Manufacturing (LCM)' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Functionally Graded Materials (FGMs) were developed for applications where a continuous, stepped or spatial change in composition and/or microstructure is required. In recent years, an interest has been given to Functionally Graded Ceramics (FGCs) since high-complex technical ceramics are increasingly requested in almost every field of applications. In the past, conventional methods have been used for the production of FGC components. However, these methods have limitations in production of custom and complex-shaped ceramic parts.  Lithography-based Ceramic Manufacturing (LCM), a recently developed additive manufacturing method by Lithoz GmbH and is used successfully for the cost-efficient, fast and near-net-shape  production of monolithic ceramics. In the GraCerLit project, a new LCM printing setup will be designed and the open platform LCM printer prototype will be adapted that allows manufacturing of ceramic-ceramic FGCs without composition and geometry limitations. FGC samples will be produced and characterized in terms of mechanical, physical and microstructural properties. The process-structure-property (PSP) relations of FGC samples will be established through regression analysis by applying Machine Learning (ML) algorithms. The project will be carried out by the experienced researcher (ER) Dr. -Ing. Serkan Nohut who has wide experience on statistical characterization of advanced ceramics and generation of PSP relations. The ER will collaborate with the supervisor Dr. Martin Schwentenwein who has a strong background in manufacturing ceramic components by LCM method and experience on execution and management of EU funded research projects. The technical knowledge and professional skills that will be gained by the ER during the GraCerLit project will make great con
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Graphene Tunneling Accelerometer', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The commercialization of existing tunneling accelerometers is hindered by their complex fabrication and long-term instability. Based on our results and expertise from the currently running ERC project, we propose an innovative design using graphene as the game-changing material for tunneling accelerometers.  The proposed graphene tunneling accelerometer has clear technical advantages, such as smaller size, wider bandwidth, simpler fabrication, and natural stability. A careful patent search indicates that the concept is novel for patent protection. Our industrial contacts have clear interest in this innovation, detailed user requirements on the accelerometer specifications have been recently mapped up. We have a capable team and a feasible plan towards the real-life commercialization of the proof-of-concept innovation. The output of the project is expected to be a long-pursued efficient application of graphene in high-end sensors. Continuity of the development and commercialization is strongly considered also after the project funding.


**Keywords:** graphene, tunneling, NEMS, accelerometer
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Performance Improvement for Vehicles on Track 2' (PIVOT2).

assistant: **Innovation**

PIVOT2 is a continuation of the PIVOT project which was scheduled to finish in September 2019.PIVOT2 will build on the work and concepts of PIVOT and move all of these concepts to higher TRL levels.The overall ambition of PIVOT2 is to develop technologies that are lighter, more energy efficient, more comfortable for passengers and with a lower impact on the track, thereby reducing the life cycle cost not only of the vehicle itself, but of the entire railway system. Technologies that increase the operational reliability of trains, causing less travel disruptions, ensuring that passengers get to destination on time and delivering a better service are also objectives. It is expected that technologies developed should automatically promote the increase of the transport capacity of railway lines.The ambitions of Shift2Rail, which are inherited by PIVOT2, require substantial ground-breaking improvements in the six key technology areas addressed by the project. Indeed, current vehicle solutions are getting closer to their enhancement limits and new radical proposals must be envisaged to accomplish the goals. PIVOT2 will be dealing with the same five key technical demonstrator (TD) areas that were advanced in PIVOT, these are Car body shell, Running gear, Brakes, Accessibility and Doors and Modular Interiors. Within these areas the results are expected to achieve a TRL 7. A new TD for Heating, Ventilation and Air Conditioning (HVAC) has been added which should achieve a TRL 4.


**Keywords:** Carbody shell, Running gear, brakes, Entrance Systems, Doors, Modular Interiors, HVAC
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Characterisation of immune response in mice expressing dream dominant negative'.

assistant: **Objectives**

The Naranjo's group identified a new transcriptional repressor, named DREAM (Downstream Regulator Element Antagonist Modulator) that binds a region DRE located downstream from TATA box in target genes. This transcriptional repressor is expressed in brain, thymus, thyroid gland and testis and the repression is relieved by PKA- and calcium-dependent pathways. The goal of this project is to determine the function of DREAM in T cells by using transgenic mice expressing dominant negative mutants of DREAM. The Ick promoter is used to drive T cell-specific expression of the transgene. I shall characterize the phenotype of transgenic mice by studying T cell development in thymus: the number of T cells and the expression of various surface markers will be compared between wild-type, heterozygous and homozygous littermates. The effect of DREAM on negative and positive selection of thymocytes will be also investigated. We expect defective T cell ontogeny in transgenic mice. In order to evaluate the function of T cells at the periphery, we plan to use the Tet-off system. The capacity of transgenic mice to mount a proper immune response after immunization will be studied in mice supplemented with tetracycline. Since the expression of FasL and Hrk is controlled by DREAM, the effect of dominant negative mutants of DREAM on apoptotic process will be particularly assessed.