RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Cost-effective, Multilingual, Privacy-driven voice-enabled Services' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Besides visual and tactile, the Next Generation Internet will rely more and more on voice interaction. This technology requires huge amounts of speech and language data in every language to reach state-of-the-art performance. The standard today is to store the voices of end users in the cloud and label them manually. This approach raises critical privacy concerns, it limits the number of deployed languages, and it has led to market and data concentration in the hands of big non-European companies such as Google, Facebook, etc.COMPRISE defines a fully private-by-design methodology and tools that will reduce the cost and increase the inclusiveness of voice interaction technology through research advances on privacy-driven data transformations, personalised learning, automatic labelling, and integrated translation. This leads to a holistic easy-to-use software development kit interoperating with a cloud-based resource platform. The sustainability of this new ecosystem will be demonstrated for three sectors with high commercial impact: smart consumer apps, e-commerce, and e-health. COMPRISE will address the mission-oriented challenges of privacy-by-design, inclusiveness, and cost-effectiveness in a sector-agnostic way; allow virtually unlimited collection of real-life non-private quality speech and language data; enable businesses in the Digital Single Market to quickly develop multilingual voice-enabled services in many languages; allow all citizens to transparently access contents and services available in other languages by voice interaction in their own language; result in cost savings for both technology providers and users.COMPRISE will find application in many sectors beyond those demonstrated, e.g., e-government, e-justice, e-learning, tourism, culture, media, etc.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Electronic structure and magnetic properties of strongly correlated transition metal materials' to be submitted under Sixth Framework.

assistant: **Abstract**

Materials with strong electronic Coulomb interactions are of great interest for industrial and technological applications due to their unusual properties, e.g. metal-insulator transitions, exotic magnetic properties etc.The overall subject of the present research project is:(1) to study the magnetic and electronic properties of strongly correlated materials from first principles and(2) the development/improvement of the numerical and analytical tools for their description.The project aims at bridging the existing gap between model calculations and electronic structure calculations for real compounds. The recently developed dynamical mean field theory (DMFT) in combination with density functional theory within the local density approximation (LDA) is a key method, which will be used throughout the project. DMFT includes the local aspects of electronic correlations in a fully dynamical manner and allows for a quantitative determination of the phase diagram and excited state properties. Very recently, a non-local extension (cluster-DMFT) scheme has also been developed. Using these techniques, the magnetic and electronic properties of transition metal oxides will be studied.Specific applications concern Mott-insulating titanates and vanadium oxides, in particular VO2, which exhibits a temperature-induced metal-insulator transition of mixed Peierls-Mott-Hubbard character. We will further develop the method towards technologically important applications such as electrically conductive heterostructures. From these cutting edge electronic structure calculations we will obtain insights into the physics of strongly correlated compounds and contribute to paving the way towards materials design with potential applications in nanoelectronics.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Development of a surveillance system and integrated biological control (ibc) programme for curbing re- emerging malaria in uzbekistan and kazakhstan' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

Suppression of vector mosquitoes and subsequent elimination of malaria using traditional chemical insecticides is not feasible due to the resistance mosquitoes have developed to toxic substances and the effect these compounds have on the environment. Thus the development of an integrated biological (IBC) programme which is targeted specifically against the vector species with minimal impact onion-target organisms and the environment represents a rational solution to thesuppresion of malaria. Thus we propose, in this project, to develop and implemental mosquito abatement program based on the utilization of environmentally friendly control measures to reduce vector mosquito populations and suppress or eliminate malaria from the afflicted areas. The benefits of such a project include strengthening scientific and technological capacities of the host country as wells improving the economy in general.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Explore Your Brain 2.0: a maximally effective, usable and scalable growth mindset intervention to break through adolescents’ declining rates of motivation and school achievements' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Adolescence is a period of sharp declines in school motivation and achievement, with negative consequences not only for the academic success and mental wellbeing of youth, but also for teachers and parents. An interesting target for intervention is adolescents implicit belief that their abilities are malleable (growth mindset), which has been shown to protect against declines in motivation and achievement, and to boost resilience in school and beyond. This PoC builds on the innovative growth mindset intervention Explore Your Brain (EYB), developed in the ERC StG BRAINBELIEFS. EYB uniquely combines theoretical information about brain plasticity with an experience of influence over ones own brain, generated using neurofeedback. The results were very promising, but the technology is still in applied research status and not yet easily usable by teachers in the classroom. The main goal of this PoC is to drastically increase the impact that we can achieve on academic motivation, achievement and resilience of high school students by improving our prototype growth mindset intervention. The breakthrough of the innovation depends on increasing usability (Objective 1) and scalability (Objective 2), to maximize the number of adolescents who can profit from the innovation. To reach Objective 1, a Research & Development team including game designers and education specialists will iteratively develop and test Explore Your Brain 2.0 (EYB 2.0) adopting a users-as-designers approach. To reach Objective 2, a Business Development team will develop a business plan for financially and logistically feasible large-scale implementation of EYB 2.0.After completing this project, we hope to implement EYB 2.0 nationally as well as internationally at a large scale, thereby protecting a maximum numbe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Role of TGF-B pathway in tumourigenesis'.

assistant: **Innovation**

TGF-ss signalling pathways play an important role in embryonic development as well as intumouri genesis. TGF-ss signalling results in nuclear accumulation of active Smads complexes that regulate transcription of target genes. Alteration of certain TGF-ss pathway components is a frequent event in some human tumours such as colorectal or pancreatic tumours and mainly results from mutation or deletion of either the TGF-ss type II receptor or the Smad4 genes. More frequently however, human tumours tend to express lo w levels of either the type I or type II TGF-ss receptors.The mechanism by which the TGF-ss pathway contributes to tumour progression is unclear, but it is now known that it can act both as a tumour suppressor by inhibition of growth or as a tumour promoter by increasing motility and inducing epithelial to mesenchymal transition (EMT), invasiveness and metastasis. My project aims to understand how alteration of TGF-ss pathway components in tumours could explain how tumour cells become resistant to the growth in hibitory effects of TGF-ss, whilst maintaining responsiveness to the pro-oncogenic activities of TGF-ss. To assess this question, I will use inducible siRNA technology to generate human pancreatic cell lines that are specifically knocked-down for Smad4 or the type I TGF-ss receptor.The functional responsiveness of these cell lines to TGF-ss will be investigated by cell cycle analysis and migration assays and I will attempt to determine whether these cells have acquired a more aggressive phenotype by measuring their tumour igenicity. These results will be complemented with micro array analyses in order to determine which target genes are implicated in these different responses.Finally, using biochemical approaches in the inducible Smad4-siRNA pancreatic ce
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on '6th World Congress of the Bernoulli and IMS societies'.

assistant: **Concept**

The proposed LCF is the Sixth edition of the joint meeting of the Institute of Mathematical Statistics and the Bernoulli Society for Probability and Statistics. These joint meetings take place every four years and are major worldwide events in Probability and Statistics. The meeting is addressed to specialists, postgraduate students and young researchers with an interest in Mathematical Statistics and Probability. In this context, the meeting will offer a unique opportunity of putting in contact young students and scientists from Europe with the main leaders from America in Probability and Statistics. Furthermore, young students and scientists from Europe will be able to discuss and exchange ideas with their colleagues from other parts of the world. This will be very helpful to promote future collaborations and exchanges. The program covers a wide range of topics in statistics and probability, presenting recent developments and testate of the art in a variety of modern research topics and in applications such as mathematical finance and statistical bio informatics. The program include up to twelve Special Invited Lectures given by leading specialists, thirty-five Invited Paper Sessions and a large number of contributed talks.The Invited Paper Sessions will include, among others, the following topics:Biological networks- modelling and inference Statistical genetics Communication schemes and randomised algorithms Compression and analysis of massive datasets Mathematical finance Applications of random matrices Brownian motion Concentration inequalities Large deviations Mixing of finite Markov chains Percolation, statistical mechanics, interacting particle systems Probability on graphs Applications of particle filtering in statistics Dimension reduction for high dimensional
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Understanding the links between functional traits and ecological processes in lake Arcellinida (testate amoebae) (‘ECOTRAIT’)' under Horizon 2020.

assistant: **Concept**

Testate amoebae, shelled unicellular eukaryotes, are common in freshwater and moist terrestrial environments. Their shells preserve well in the fossil record and species assemblages have been shown to be sensitive indicators of water quality change, and thus useful in environmental monitoring.  Whilst the ecology of the group is reasonably well understood, a determination of their role in specific ecosystem processes has been hampered by taxonomic uncertainties.  As the living cell quickly decays after death, taxonomic divisions have relied on shell morphology.  This approach is problematic as genetic analysis has shown that some species display morphological plasticity, partially in response to environment, whilst other specimens with similar morphologies have been demonstrated to be distinct ‘cryptic’ species. This project will utilise techniques used by the two research communities to develop more refined methodologies to characterize test morphology (e.g., notably functional trait analysis) to provide a powerful new framework for understanding microbial food-webs and community responses to ecological stressors over multiple time-scales. Specifically, the project will apply these interdisciplinary methodologies to examine the controls on morphology in Arcellenida, the dominant testate amoebae found in lakes to: 1. examine causes of functional trait variability in modern and palaeolimnological settings; 2. develop novel biometric trait delimitation approaches using SEM imagery and 3D imaging software; 3. use genetic sequencing on select morphospecies, to test the hypothesis that variations in shell morphology are a response to environment; 4. evaluate the significance of trait-based approaches for understanding temporal changes in species composition. This research wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Concurrent Tuberculosis and Diabetes Mellitus;unraveling the causal link, and improving care' (TANDEM).

assistant: **Innovation**

Diabetes (DM) triples the risk of developing tuberculosis (TB). Consequently, the alarming growth of type 2 DM in TB endemic countries and among people originating from TB-endemic countries poses a serious threat to global TB control.This project addresses the scarce evidence for many of the recently advocated guidelines for care and control of TB and DM, as well as our lack of understanding of the mechanisms underlying the effect of DM on TB susceptibility and treatment outcome.We will use a comprehensive and integrated approach combining clinical, epidemiological and cutting edge expertise in laboratory sciences, bringing together a multi-disciplinary consortium linking field sites in Romania, Peru, South Africa and Indonesia, with leading laboratories in Germany, United Kingdom and the Netherlands.We will define the optimal and most cost-effective ways of screening TB patients for DM diabetes, and determine the prevalence of DM among TB patients and of TB in DM patients in the four countries. With regard to treatment, we will determine the level of DM management required during and after TB treatment, the safety and pharmacokinetics of metformin when combined with rifampicin, and the effect of hyperglycemia control on TB treatment outcome. To help establish the cellular basis and immunological pathways underlying the link between DM and TB we will provide new data on: gene expression data of TB patients with and without DM; ex vivo and in vitro Mycobacterium tuberculosis stimulation data of different cell types, including macrophage subsets and adipocytes in the presence of high glucose and insulin; data regarding the role of common and more rare genetic variants in the combined susceptibility to TB and type 2 DM; and relevant functional genomics experiments.In summa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Paleogenetic extraction and analysis from challenging environments' to be submitted under Horizon 2020.

assistant: **Abstract**

The field of ancient human DNA (aDNA) has rapidly undergone changes over the last decade. These changes have been spurred on through the use of high-throughput sequencing (HTS) technologies. These methodological advancements have increased our understanding of the human lineage to depths thought impossible only a short time ago. For example, aDNA research has shown how modern humans are related to our archaic ancestors, indicating significant admixture events throughout our evolutionary history with the Neanderthals and other now-extinct archaic species. However, to achieve these results, the ancient material has been exceptionally well preserved, owing to favorable, i.e. cold, environmental conditions. For many parts of the world, however, the environmental conditions remain a barrier to the extraction and analysis of aDNA. The nature of aDNA research is inherently interdisciplinary, whereby several branches of inquiry, such as archaeology or genetics, attempt to answer similar evolutionary questions from different perspectives. This proposal attempts to use advanced extraction and sampling methods for aDNA from challenging environments in order to broaden the scope of paleogenetics research. Although continental Europe has gained significantly from these advances, for other parts of the world, such as Southeast Asia and the Near East, this has been more difficult due to formidable preservation conditions. The goal of this proposal is to build on promising preliminary results that target a specific bone in the human skull in order to gain a better understanding surrounding the dynamics of aDNA preservation, while at the same time, gain insight into the evolutionary histories of peoples from warm and humid, or warm and arid, locations. Our proposal incorporates state-of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Multidisciplinary networking of research communities in FIRE' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The objective of the MyFIRE project is-\tthe multidisciplinary networking of research communities addressing both technological, socio-economical and environmental aspects of the Future Internet-\tthe coordination of research experience and user-driven open innovation activities establishing common concepts, roadmaps, methodologies and tools, based on standardised approaches.MyFIRE project develops the efficient  mechanisms of test beds process to make it more effective and used. MyFIRE identifies the user communities and their needs for improving research value of the huge investments in FIRE testbeds.MyFIRE develops a unique and new approach addressing the optimisation, the design, the set up and the use of the experimental test facilities by increasing awareness on economic data and technical related best practicesThe MyFIRE project will apply a methodology known and successfully used by its partners in previous support projects. The approach is to create a supportive environment, which enables key stakeholders to focus on the central question, develop consensus and collectively develop and agree on best practices for testing facilities across the scientific community.MyFIRE project will create an environment providing the awareness for the efficient development of experimental facilities in Europe in collaboration with international partners, especially in the BRIC countries. This will reflect the balance between the requirements for strong collaboration and the stakeholders expectations thus achieving the good experimental activities to develop the sustainable testing methodologies able to contribute to European standards development. The framework will be developing through the creation of open dialogue between the ICT networking research communities and experts f