RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'open INnovation Ecosystems for Do It Together process' (INEDIT) targeting Horizon 2020.

assistant: **Abstract**

INEDIT creates an open innovation European DIT ecosystem for sustainable furniture co-creation. It channels the creativity of consumers, shapes it through designers’ professional skills, and makes it viable by leveraging on the expertise of production specialists in order to deliver sustainable, smart and personalized new products in a shorter time to market. INEDIT intends to demonstrate the capacity to turn the well-known ‘Do It Yourself’ (DIY) approach applied by individuals within FabLabs into a professional approach named ‘Do It Together’ (DIT). The DIT approach will be applied by customers and professional producers, especially SMEs, for conveying higher customer satisfaction through customer-driven production. DIT is a novel approach capitalizing on the knowledge, creativity and ideas of design and engineering conceptualized by interdisciplinary stakeholders and sometimes even new actors. It is powered by existing European innovation ecosystems shaping new products across EU countries. INEDIT demonstrates the approach through four cross use cases with high societal impact: sustainable wood panels manufacturing and 3D-printing of wood, 3D printing of recycled plastic and ""smartification"". Sustainability and consideration of individual preferences, especially of women and men, will be our guiding thread. INEDIT addresses societal challenges such as contribution to reduce the amount of produced CO2 in focusing on European-wide production, creation and maintenance of EU-wide job opportunities. This will lead to new business opportunities supported by business model innovation. Moreover, these innovative networked local manufacturing competences and production facilities across the EU will solve ethical concerns within the manufacturing network. INEDIT intends to de
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Aneuploidy and Its Impact on Blood Development: Context Matters' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Many childhood leukaemias start to develop before birth due to accumulation of mutations during foetal development. Children with trisomy of chromosome 21 (Ts21), also known as Down's Syndrome (DS), have a 500-fold increased chance of developing acute megakaryoblastic leukaemia. It is well known that aneuploidy (an abnormal number of chromosomes) is often associated with leukaemia and is likely to be driving this increased incidence of blood malignancies in children with DS. However, the mechanisms that control differentiation of haematopoietic stem and progenitor cells (HSPCs) and patterns of mutation acquisition in these cells during early human development are not well understood. This study will provide novel insights into two important questions: i) what is the impact of aneuploidy on blood formation in the context of specific tissue and ii) how it affects mutation accumulation and clonal selection in HSPCs. Here I aim to reveal cellular and mutational processes active during human Ts21 foetal blood development by: 1) performing comprehensive single-cell transcriptomics and spatial transcriptomics analysis of human Ts21 and healthy foetal liver and bone marrow combined with single-cell in vitro differentiation assays and 2) generating a catalogue of all somatically-acquired mutations in hundreds of Ts21 foetal haematopoietic progenitors using whole genome sequencing. The approach I propose derives its power from the close integration of state-of-the-art experimental data generation and computational analysis using novel methods. By examining cell intrinsic vs extrinsic processes in Ts21 haematopoiesis as well as mutation accumulation in individual stem cells this study will provide unprecedented insight into the mechanisms by which cellular changes induced by aneup
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Mechanisms of radiation induced genomic instability and bystander effect' (1998-2002) under Fifth Framework.

assistant: **Objectives**

The main aim of the project is to investigate processes leading to destabilisation of cells after exposure to ionising irradiation. We will, in particular, concentrate on non-targeted " phenomena such as bystander effect and genomic instability. The underlying hypothesis is that radiation induces a variety of "sensors" and "alarm signals " in cells, which could be expressed as bystander effect and genomic instability. The ultimate aim of the present study is to identify mechanisms, possible relationship and biological meaning of bystander effect and genomic instability. We plan to use three different protocols of irradiation: conventional broad field, medium transfer technique and microbeam irradiation (microbeam facility is available at Gray Cancer Institute).We plan to use hTERT-BJ1 normal human fibroblasts and hTERT-RPE1 normal human epithelium cell lines which are telomerase-immortalised. This enables us to study effect of irradiation within a wide time frame. A variety of endpoints planned to be used in the present study. Generally, they could be divided into two major categories either related to cellular response (apoptosis, cytogenetic markers and protein expression) or signalling between cells (intercellular communication, expression of connexins). The study of non-targeted effects of radiation is important for understanding the dose- response mechanisms relevant to low-dose natural (i.e. due to Radon) irradiation in vivo and radiation protection issues.The present project gives a unique opportunity to investigate mechanisms of genomic instability and bystander effect in two human cell lines with an infinite life span. Wide arrays of conventional and innovative techniques are planned to be used. The applicant would benefit from learning of new techniques such a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Smart Implant for Magnetic Anastomotic Healing and Leakage Evaluation'.

assistant: **Objectives**

Colorectal cancer affects over 1.93 million people worldwide each year. In most cases, surgery to remove the tumour is necessary, and intestinal continuity is restored through an anastomosis. However, a serious complication, known as an anastomotic leak, occurs in up to 20% of procedures. This complication is associated with high mortality rates, frequent re-interventions, prolonged hospital stays, increased healthcare costs, and a reduced quality of life. Despite decades of research, the incidence of anastomotic leaks remains high, largely due to poor healing and delayed recognition.Leveraging outcomes from the FET Open project '5D NanoPrinting', and EIC Project 'IV-Lab', Trinity College Dublin and the Istituto Italiano di Tecnologia, in collaboration with Plio Surgical and Amsterdam UMC, aim to integrate the results of micro-sensor and nano-printing technologies into a disruptive smart magnetic anastomosis implant. This innovative implant will offer both healing and sensing capabilities, monitoring physical and chemical parameters that signal inflammation and edema at the anastomosis site.The SMARTHEAL project will advance this technology from TRL 3 to TRL 6 by embedding micro-sensors within the implant to detect key markers of anastomotic leaks. These sensors will be integrated with wireless electronics to transmit real-time data on healing biomarkers, with the implants accuracy demonstrated in pre-clinical models.SMARTHEAL represents a groundbreaking advancement, being the first implant to simultaneously enhance healing and enable early leak detection. This innovation has the potential to significantly improve surgical outcomes and reduce healthcare costs globally. It offers a substantial commercial opportunity for Plio Surgical, which aims to undertake the clinical
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Dynamic markers' in the context of a Fifth Framework call.

assistant: **Objectives**

The scientific aspect of the project is-a change of the angular moment of a super paramagnetic crystal, through an interfering magnetic field (microscopic reaction). The technical aspects result, consequently, from the macroscopic reaction of the crystals due to upper field interference. The DM technique will extend the well-known passive marking techniques, such as the magnetic cell sorting systems of today, to active dynamic ones. This will be achieved by special magnetic fields and field combinations of magnetic fields, which are produced and run on the outside of, for instance, vessels which contain liquids with the marked objects - among others - in it. Objects (e.g. cells) which are marked by. active" super paramagnetic crystals, can be moved in very special ways and therefore observed between plenty of others, with a very high selectivity (diagnosis). DM techniques will also work as rapid (hereby escaping attacks by the bodies own defence system) transportation mechanisms, e.g. for artificially made phospholipid vesicles containing small amounts of drug solutions (therapies). DMtechniques can combine dynamic and static effects, which means that marked antibodies can be transported very rapidly in liquids such as blood, to certain areas, where long term - or short term barrier structures can be established (useful in fighting the spread cancerous cells to..."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Cognitive and Cooperative Signal Processing Technologies for Remote Sensing Applications' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Cognitive and cooperative sensing is a novel concept in signal processing that promises to revolutionize the way we interpret and understand our world. It has even been hailed as “a way of the future” in remote sensing networks . Smart or intelligent sensor networks have the potential to impact almost every aspect of our lives through applications such as smart homes, environmental monitoring, security, disaster detection and assessment, noninvasive health monitoring, and traffic information systems. Remote sensing refers to the ability to extract information about the properties or nature of a phenomenon without coming into direct contact. Typically, this is accomplished by exploiting sensors such as cameras, radar systems, thermal devices, sound detectors, seismic, and magnetometers. Cognitive and cooperative sensing envisions not just the fusion of information gathered from multiple sources, but intelligent data gathering geared towards removing the need for human intervention, capable of adaptively controlling and selecting sensors within the network for optimal performance. Our research forms a key stepping stone towards achieving this ultimate goal by pursuing several tasks that can be grouped into two primary categories: 1)Detection, estimation, and tracking algorithms for cognitive, distributed sensor networks, and 2)Multi-sensor intelligent information fusion. This research project holds promise to yield significant advances in a variety of applications, which are defined as main research challenges in the FP7 ICT, Environment and Security Themes of the 2010 Workprogramme, at a time when the application of cognition to remote sensing is still in an embryonic stage. We have played a significant role in initial research relating to this project, and are therefore
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Innovative Solutions in Future Stations, Energy Metering and Power Supply' under Horizon 2020.

assistant: **Concept**

Innovative Solutions in Future Stations, Energy Metering and Power Supply (IN2STEMPO) addresses the call S2R-CFM-IP3-01-2017 Smart System Energy Management Solutions and Future Station Solutions.  IN2STEMPO aligns with the Shift2Rail objectives and aims to reduce lifecycle costs, improve reliability and punctuality, whilst increasing capacity, enhancing interoperability and improving the customer experience.The IN2STEMPO Smart Power Supply activities seek to contribute to the development of a railway smart grid based on the development of an unique railway power grid in an interconnected system. This new railway network will integrate smart metering, innovative power electronic components, energy management and energy storage systems.  This new concept will lead to improved and optimised train traffic, energy costs, and energy supply security for the railway system.  In parallel it will allow for optimised solutions to be developed through optimising investment, operation costs and maintenance. The IN2STEMPO Smart Metering research activities will realise a non-intrusive smart metering sensor network at a railway system level. It will demonstrate an open system and interface for data collection, aggregation and analysis at an open source ODM (Operational Data Management) level. The applications will exploit the energy analysis process with the aim of enhancing energy decision-making and line operation patterns.  Other possible applications include preventative maintenance plans, asset management and Life Cycle Cost dashboards.The IN2STEMPO Future Stations activities are aimed at improving the customer experience and safety at stations, resulting in a better passenger experience for customers using the railway. Research will be focussed on improving crowd management in h
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Cyber-Infrastructure for civil protection operative procedures' (CYCLOPS), addressing dissemination and exploitation.

assistant: **Impact**

The Global Monitoring for Environment and Security (GMES) concept was endorsed by the EU Commission in 2001 with the aim of establishing by 2008 a European capacity for Global Monitoring of Environment and Security". The challenge for GMES is to design innovative value-added services to enable decision makers to better anticipate or mitigate crisis situations and management issues related to the environment and security. The Final Report for the GMES Initial Period recognised the European Civil Protection (CP) as one of the GMES service categories.This report outlines the importance to develop e-infrastructures to serve GMES applications. Indeed, the EU EGEE (Enabling Grids for E-Science in Europe) project provides a powerful platform to support specific application Communities. However, GRID evolution has mainly focused on technology, while, GMES services have mostly been user-oriented. Thus, there is a need of cross-disseminating requirements and visions of the diverse Communities. CYCLOPS brings together GMES and GRID Communities, focusing on the operative sector of European CP. The main objectives of CYCLOPS are:1) To disseminate EGEE results to the CP Community, assessing EGEE infrastructure for CP applications. Activities will include training, workshops.2) To provide the EGEE Community with knowledge and requirements characterizing CP services. 3) To evaluate the possibility to utilise the present EGEE services for CP applications, developing the research strategies to enhance EGEE platform.4) To develop the research strategies to enhance EGEE platform, especially for Earth Sciences resources.CYCLOPS will contribute to the EU policy developments establishing synergies with other existing projects and initiatives dealing with GMES, GRID and complementary sectors,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Electrochemical control of biofilm-forming micro-organisms: screening, identification, and design of new knowledge-based technologies' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Most of the micro-organisms growing in natural environments form biofilms on solid surfaces, that are mainly known for their adverse effects on human health and industrial / consumer's goods. A concept of electrochemically active biofilms has recently emer ged from a few studies discovering that some bacteria forming biofilms on conductive materials can achieve a direct electrochemical connection with the substrate using it as electron exchanger, without the aid of additional mediators. This capability of so me micro-organisms to plug" their metabolisms directly in an external electrical power supply is very exciting and opens new perspectives for pioneering research. Indeed, the exploitation of micro-organisms natural metabolisms to catalyse or to control el ectrochemical reactions, which naturally occur in our environment or which are created by man, should lead to major technology breakthroughs and the to the development of new products and processes, in many fields like bio-energy, bioremediation, biofou ling prevention, biosynthesis processes, bio-corrosion mitigation and biosensor design. The partners experts in microbiology, electrochemistry, material and chemical engineering will joint efforts in the project during three years, to decipher the mechanis ms responsible for the biofilm's formation, to identify a wide range of micro-organisms capable to colonise different types of industrial materials in different media and under different process conditions, and to assess the feasibility of new technolog ies and applications based on the new concept. The proposed research clearly lies in a multidimensional area with novel multi-disciplinarity, not covered by any of the thematic priorities. It is expected that generic mechanisms and key functions in micro-o rganism'
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'INTerEthnic Relationships in contemporAry CommuniTies: How does ethnoracial diversity affect in- and out-group trust, solidarity, and cooperation'.

assistant: **Objectives**

The increasingly multiethnic nature of modern societies has spurred academic interest in the consequences of diversity. Recent scholarship has linked ethnoracial diversity to undesirable collective outcomes, e.g., low levels of trust, civic engagement, and social capital. These findings have important policy implications, in part because they resonate with public anxieties about immigration, residential integration, and the role of the welfare state. The proposed research will investigate the micro-mechanisms through which contact promotes or impedes solidarity and cooperation in diverse communities. More generally, this research moves beyond communitarian conceptions of social capital to understand the building blocks of solidarity in contemporary, diverse societies. To investigate the micro-level dynamics that link intergroup contact to solidarity and cooperation, this project takes an innovative field-experimental approach, which moves beyond observational data. In particular, the project uses lab-in-the-field experimental games to assess the dispositional mechanisms – such as generalized altruism, group solidarity, reciprocity, and sanctioning – that bring about solidarity and cooperation in various group settings.This revised version of the proposal addresses all the panel observations and implements changes accordingly. First, I have limited the research to project 3 (P3), and cut projects 1 (P1) and 2 (P2). Second, the duration of the project has been reduced to 48 months. Third, all expenses related to P1 and P2 have been cut.