RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Intelligent needle tracking using ultrasound imaging for improved minimally invasive interventions' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Developments in medical care are driven by increasing patient care quality and reducing cost. In the field of anaesthesia, the use of regional techniques has led to improved patient outcome and reduced costs compared to general anaesthesia. However, only 60% of anaesthesiologists perform peripheral nerve block procedures regularly. A wider adoption is hindered by lack of adequate technology. Currently they are largely navigating “in the blind”, using indirect measures as well as their anatomical experience to decide where they should inject. The INTUI-VIEW solution will change this.In the INTUI-VIEW project, Philips, B.Braun and Oslo University Hospital are partnering in order to bring an ultrasound tablet solution with needle tracking technology to the market. The solution is a revolutionary and new technique. It will speed up transition from general anesthesia to regional anesthesia. Patients will receive better, first time right regional anesthesia procedures, avoiding needle misplacements. The clinicians will receive a tool allowing them to do a safer, faster job with more predictable outcome. Finally, it will help hospital and health care systems to be more efficient by avoiding to waste expensive and limited resources.The scope of the project is to finalize the development of the INTUI-VIEW platform towards market introduction, industrialise and validate it in clinical settings, obtain regulatory approval and prepare market launch (2017). The two industrial partners are targeting a turnover of EUR 110 Mio in 2024, and a cumulative sales volume of EUR 700 Mio in 2024. Market adoption is expected to be 14% globally which translates into the treatment of 4.6 mln patients with INTUI-VIEW in 2024.In total, about 143 jobs will be created in both companies. In the R&D ph
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Investigating the consequences of birth by Caesarean Section in hypothalamic and Amygdalar neuroVAscular deveLOpmeNt' (AVALON).

assistant: **Concept**

Early postnatal development is a vulnerable period during which environmental faEarly postnatal development is a vulnerable period during which environmental factors significantly influence brain development. Among these factors, the gut microbiota has been found to impact brain function and development. However, there is a lack of mechanistic understanding regarding how changes in early-life microbiota composition can lead to brain dysfunction. Caesarean-section (C-section) delivery, while life-saving in some cases, is becoming more common even when not medically indicated. This trend raises concerns about the disruption of perinatal microbiota and its potential impact on newborn brain development. My preliminary data showing neurovascular dysfunction in C-section-born neonatal mice support my hypothesis. Building on this foundation, AVALON aims to investigate the interactions between neonatal microbiota and neurovascular development in the hypothalamus and amygdala at molecular and cellular levels. I will utilize a C-section mouse model to disrupt early-life microbiota and assess its impact on neurovascular development through in-vivo tracer imaging and integrated multi-omics analysis. Additionally, I will use a reporter mouse line to trace amygdalar and hypothalamic neuronal populations. I will also identify key microbial functions that modulate neurovascular and neuronal development. Furthermore, I will explore the potential of precision probiotics to mitigate microbiota-induced deficits, offering valuable translational insights. AVALON will significantly contribute to my career by providing training in both academia and industry, enhancing my research skills, and expanding my professional network. To ensure broad awareness of AVALON's outcomes, a dissemination stra
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Concurrent Environment And Architecture For Telecollaboration Integrated In The Company'.

assistant: **Concept**

C-ARCTIC proposes the development of a new technology for concurrency, based on the concept of Synchronous Object. This will be achieved by developing an environment called COLD, for the development of software applications based on its principles, in Java language. This environment will be tested by means of the development of a software platform, ARCTIC, based on Synchronous Objects, for integrated telecollaboration on Intranet/Internet. The telecollaboration platform and the underlying technology will be finally tested and assessed by means of three different telecollaboration scenarios.Six organisations will cooperate:one University that brings the technology and coordinates the development of COLD;two industrial companies adopting the technology and applying it in ARCTIC;a consultancy in work issues, collaborates in the specification of ARCTIC;two user companies that will put test scenarios.Objectives:The main objectives of C-ARCTIC are:1.The realisation of an environment and methodology for the development of robust distributed software applications implementing an innovative technology for concurrency. That technology is based on Synchronous Objects in Java. Both, environment and methodology will constitute a framework called COLD for the development of such kind of applications.2. The application and testing of COLD, in the development of a distributed architecture able to support the implantation of custom telecollaboration models in companies, based on the technology of Synchronous Objects. The result will be a software platform, ARCTIC, composed by a set of software tools and complemented by a methodology guiding its custom implantation.3. Testing and feedback of both the Synchronous Objects technology and its application in ARCTIC, will be done by means of t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Wood fiber-plastic composites form recycled woodfibers and recycled polymers' (1994-1998) under Fourth Framework.

assistant: **Objectives**

A feasibility study concerning the production of wood-plastic composites utilising recycled wood fibers and recycled polymer waste granulates. Wood-plastic composites can be produced using: a. either extrusion technology or co-extrusion technology b. mouldpress technology The economic purpose is to obtain a raw material - as a composite of plastic and woodfibers - which has greatly increased strength and less shrinkage or expansion than pure plastic products. Besides the raw material is considerably cheaper than virgin material. The technical objectives are to develop: a. a process technology for the production of an optimal homogeneous mixture of wood and plastic residuals; b. a screw geometry which enables to press the melt material through a die to form sheet products; c. a mould press technology for the production of three dimensional mould products. The industrial objective is to design wood-plastic products with high added value at low processing costs fitting in the desired and use-requirements/qualities. * Low maintenance * water resistant * increased strength * lower shrinkage 1/5th of plastic building materials * woodlike and marble like colours * thermal isolation properties
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Modelling brassinosteroid signalling in vascular development' (MOBSIV) targeting Sixth Framework.

assistant: **Abstract**

Brassinosteroids (BRs) are plant steroid hormones that regulate a variety of growth and developmental processes. Whether BRs are required and how their binding to particular receptors generates specific cell differentiation patterns in the context of a dev eloping organ is still unknown. The plant vascular system is composed of two tissue types, xylem and phloem, which originate from procambial stem cells that proliferate and differentiate to form vascular strands connecting all different parts of the plant.The main objective of the project included in this proposal is to analyse the contribution of the BR-responsive BRI1/BRL1 and BRI1/BRL3 pathways in setting up the proliferation and/or differentiation of xylem and phloem tissues from pluripotent vascular s tem cells, using Arabidopsis thaliana as a model system. To reach this objective, I plan to use a multidisciplinary approach combining cell biology techniques, molecular genetics, plant physiology and genomics.My final long-term goal is to bring together all the biological information on the role of BRs in vascular development using mathematical modelling. The proposed approach will provide further insights into the functional role of BRs in vascular development, their interplay with auxin and their potential application for crop improvement.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Machine for Microparts Moulding based on UltraSound excitation'.

assistant: **Concept**

A breakthrough concept in the manufacture of plastic micro and mini parts: the SONO“R”US Project will introduce into the market the first moulding machine based on the ultrasounds. Taking profit of previous results achieved by Sonoplast (Collaborative Project from the FP7), SONO“R”US intends to develop an optimized, ready-to-market ultrasonic moulding machine.Following an increasing trend in miniaturization, the project has an impact in economically strategic areas like biomedicine, electronics, optics, precision engineering, etc. In this context, injection moulding has proved to be the most precise, flexible and profitable technology for large-scale replication of thermoplastic parts. However, the solutions available for micromoulding simply adapt the concepts used for bigger parts. That perfectly explains the limitations in terms of dosage, accuracy and repetitiveness.Sonoplast has demonstrated that, up to now, ultrasound injection moulding is the only technology able to face those technical difficulties. The project culminated in a fully functional prototype which allowed validating the new technology and producing high quality parts. Even though, there are still relevant points that must be improved in order to successfully introduce the machine in the market and exploit new market niches.Therefore, the goal of SONO“R”US is to deliver a machine perfectly adaptable to market needs. This equipment must de developed according to new parameters of ultrasounds while complying with technical requirements of micromoulding, like repetitiveness, quality, profitability, etc. Our main challenge is to produce micro and mini parts featuring very complex geometries through a higher of dosage.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Development of a technology for the industrial production of cationic flour' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The subject of this R&D project is to replace cationic starches (chemically modified starch products), which are used in technical applications in the non-food area, by adequate cationic flour (wheat, rye). The project can be sub-divided into two areas: a) On the basis of known reaction processes for the cationisation of polysaccharides (starch), appropriate new processes are to be developed for the cationisation of flour. A particularly important task is on the one hand to characterise these new types of raw materials (flour is a complex system containing primarily starch, pentosan and protein) regarding their specific reaction condition an the product features and on the other hand to determine these by means of appropriate methods. b) Use of the cationic flour in the areas of application in question On the basis of the specific properties of the cationic flour, existing and new applications can be derived, developed and put into practice.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'A European volcanological supersite in Iceland: a monitoring system and network for the future' (FUTUREVOLC) under Seventh Framework.

assistant: **Objectives**

The main objectives of FUTUREVOLC are to establish an integrated volcanological monitoring procedure through European collaboration, develop new methods to evaluate volcanic crises, increase scientific understanding of magmatic processes and improve delivery of relevant information to civil protection and authorities. To reach these objectives the project combines broad European expertise in seismology, volcano deformation, volcanic gas and geochemistry, infrasound, eruption monitoring, physical volcanology, satellite studies of plumes, meteorology, ash dispersal forecasting, and civil defence. This European consortium leads the way for multi-national volcanological collaboration with the aim of mitigating the effects of major eruptions that pose cross-border hazards. Iceland is selected as a laboratory supersite area for demonstration because of (i) the relatively high rate of large eruptions with potential for long ranging effects, and (ii) Iceland’s capability to produce the near full spectrum of volcano processes at its many different volcano types. Based on present monitoring networks and ongoing research, the project will bridge gaps and combine efforts for a coherent close-to-real-time evaluation of the state of Icelandic volcanoes and their unrest. The project will provide timely information on magma movements from combined interpretation of earthquake sources relocated in three-dimensional velocity models, magma sources inferred from ground and space geodetic data, and measurements of volcanic volatiles. For better response during eruptions, the project will develop operational models of magma discharge rate, contributing directly to improved forecasts of ash dispersion. They will help to minimise economic disruption on a European scale during eruptions. By int
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Microbiome Influence on Energy balance and Brain Development-Function Put into Action to Tackle Diet-related Diseases and Behavior.'.

assistant: **Concept**

Emerging evidence indicates that the gut microbiome contributes to our ability to extract energy from the diet and influences development and function of the immune, endocrine and nervous systems, which regulate energy balance and behaviour. This has led to hypothesize that developing microbiome-based dietary interventions can be cost-effective measures to prevent diet-related and behavioural disorders. Yet this approach is restricted in practice by a lack of understanding of the specific species that contribute to these disorders and their interactions with host and lifestyle determinants. To progress beyond the state of the art, the MyNewGut proposal aims to: (1) shed light on the contribution of the human microbiome to nutrient metabolism and energy expenditure; (2) identify microbiome-related features that contribute to or predict obesity and associated disorders in human epidemiological studies; (3) understand how the microbiome is influenced by environmental factors and its role in brain and immune development and function in humans; and (4) provide proof-of-concept of the disease risk-reduction potential of dietary intervention with new foods/ingredients targeting the gut microbiome in humans. To this end, a translational multidisciplinary research strategy will be developed, combining experts in omic-technologies and all other scientific disciplines required. Consequently, the MyNewGut proposal will contribute to developing new approaches to prevent diet-related diseases (metabolic syndrome and obesity) and behavioural disorders through lifestyle changes, intake of pro- and prebiotics and semi-personalised and innovative food products. This will ultimately contribute to increasing the competitiveness of the European food industry and provide consumers with relia
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Evolution of embryonic development across the Preocial-Altricial spectrum in birds' under Horizon Europe.

assistant: **Concept**

The project proposes to make use of modern molecular, microscopic and computational tools to analyze the embryonic development of several species of birds and compare how major differences in embryonic mode and tempo develop and what consequences they have in the morphological diversification of avian clades. I will collect embryonic series of species  of several bird families that also represent independent evolutionary transitions in developmental mode and generate a large dataset of embryonic anatomical data to dissect how avian evolutionary patterns relate to developmental mode and tempo, combining tools of comparative anatomy, developmental biology, geometric morphometrics and phylogenetic inference, integrating the study of embryonic development with macroevolutionary analyses.Many recent macroevolutionary studies have highlighted the need for the use of embryonic information, yet these kind of datasets are mostly inexistent. Classical developmental biology has made use of selected species as models, representing sometimes groups of thousands of species, as has been the case of Gallus gallus for birds. Only a few other avian species have been systematically studied and these represent an uneven coverage of the diversity of avian anatomies, ecologies and life histories. The project seeks to collect detailed embryonic information of several previously unstudied avian species, and study them in the context of a series of major evolutionary transformations, in order to bridge the existing gap between developmental biology with macroevolutionary studies. The project will serve as a proof of concept for expanding this kind of new-of-its-kind framework, and will provide large amounts of information that have been classicaly associated with distinct field of biological sc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Analysis of the responses of subicular neurons to electrical and iontophoretic stimulation' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

Introduction: The mammalian hippocampal formation is comprised of the hippocampus proper, entorhinal cortex (EC) and subicular complex (subiculum, presubiculum, parasubiculum). The EC and subicular complex process and transmit information between the neocortex and hippocampus. The electrophysiology of EC and subiculum has received little attention, despite their importance in memory formation and involvement in pathophysiological changes associated with dementia and epilepsy. Experimental Outline: The production and regulation of neuronal responses in the subiculum of the mammalian brain will be determined. Recordings will be made from anaesthetized rats. Stimuli will activate the EC and hippocampal CAI inputs to subiculum. Intracellular, extracellular and laminar recording protocols will determine the steady-state responses, neuropharmacology and functional plasticity of these projection systems when activated either singly or in concert. Resultant data will provide important insights into the functions of the subicular complex as the final stage of hippocampal processing and help clarify its role as the interface between the hippocampal formation and the neocortex.