RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Assimilation of envisat data' in the context of a Fifth Framework call.

assistant: **Objectives**

ASSET is a major European initiative to exploit and develop EO data using data assimilation to: (a) develop a European capability for chemical/UV forecasting, and (b) provide analyses for climate/chemistry studies. It will provide a network for the long-term exploitation of EO data within the European Research Area concept. ASSET will add value to Envisat data by assimilation into NWP systems and photochemical models. Strategies for the assimilation of Envisat data into NWP systems will be assessed. Assimilation of Envisat photochemical data will be used to study the distribution/variability of key species such as ozone. ASSET brings together experts from all aspects of the assimilation problem: NWP, chemical assimilation, modelling, meteorology, retrieval and assimilation theory, and observations. ASSET builds on the Envisat effort. Beneficiaries include NWP agencies, ESA, climate researchers, government, industry, and the public.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Molecular Dynamics Data Bank. The European Repository for Biosimulation Data' in the context of a Horizon Europe call.

assistant: **Objectives**

After decades of development and a Nobel prize, Molecular Dynamics (MD) has reached maturity. It is no longer an exotic technique used by a small group of theoreticians but rather a method extensively used by a very large community of users. Millions of supercomputer hours are devoted to collecting trajectories, thus producing a deluge of simulation data that the community is unable to handle. A poor tradition of data sharing and the lack of appropriate infrastructures to do so lead to the loss of data after limited analysis that most likely revealed only a small fraction of the information contained. Sparse initiatives to build trajectory repositories have encountered difficulties related to: i) the lack of trust of the community in the reliability of the data deposited; ii) the lack of interoperable standards and simulation ontologies; iii) uncertainties regarding the database technology required; v) difficulties of the users to interact in an open manner with the data; and vi) disconnection of the MD-field with neighboring communities. The MDDB projects intends to design a European-scale repository of MD simulation (and associated analysis tools), which will: i) optimize computational resources; ii) favor the analysis (and meta-analysis) of trajectories for many different perspectives and fields; iii) guarantee a fast and efficient interchange of information between groups; and iv) facilitate the integration of the MD simulation field into neighboring communities. The overall result will be a more efficient use of MD and the integration of the MD field into mainstream biology and chemistry research.


**Keywords:** Molecular dynamics, Simulation databases, interoperability, big data, data standards, good practices, FAIR.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Temporal dimensions of information processing as a functional marker of mental state: evidence from schizophrenia' (2007-2013).

assistant: **Innovation**

Real-world events occur not only over extended regions of space but also over extended periods of time. On the time scale of cognition, for example, it takes a few hundred milliseconds to utter a word, a few seconds to utter a sentence, and sometimes much longer to convey an idea. The information gathered at each particular moment, however, only becomes meaningful in the context of previous events. The capacity to accumulate information over time, thus, is crucial to our functioning in an ever-changing world. Yet there is surprisingly little research on how the brain integrates information over time.This project aims to investigate the temporal domain of information processing in human brain at the network level. We will apply novel inter-subject correlation (ISC) approach for analyzing fMRI network organization evoked by continuous and complex stimulation, such as stories and movies. Recently, in healthy subjects, we revealed hierarchy of information processing over time from early sensory areas toward high order perceptual and cognitive areas. Here we will focus on demonstrating the breakdown of such processing in one of the major psychiatric disorder such as schizophrenia.Schizophrenia patients suffer from a failure to integrate information at different scales/domains including time. This project aims to implement the ISC in first-episode schizophrenia patients and their healthy siblings, which are known to be more prone to the disease. Preliminary results in the patient group demonstrated impaired hierarchy with processing intact in low level but disturbed in high level, in both visual and auditory modalities. The sibling group showed an intermediate effect. We believe that better understanding of the underlying neural circuit involved in information processing in s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Unified Framework for the Analysis of Co-evolutionary Systems' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Today's challenges are marked by more frequent and wide-spread episodes of social, economic, political and environmental crisis. Co-evolutionary systems offer a natural perspective and powerful tools to help us understand conditions that affect populations of agents whose behavior changes in response to their interaction outcomes in situations of strategic decision-making. Studying these complex co-evolutionary systems remains an open challenge as rich structures in the models are not taken into account. The overarching aim of this project is to fill this major research gap with a unified, principled framework to analyze complex co-evolutionary systems. At the core of our approach is the graph representation of interacting agent behaviors where problem structures are fully captured by complete orientations in the graph and associated co-evolutionary dynamics by sampling processes on the graph. This project combines complementary expertise of the Experienced Researcher (Dr. Chong) in large co-evolutionary systems and the Supervisor (Professor Tino, University of Birmingham) in complex, adaptive and dynamical systems. Its vision is that the framework provides foundation for new modelling tools benefiting policy-makers, regulators, and academics through better understanding and predictive quality of real-world strategic decision-making systems.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Ontogenetic transcriptome evolution in tetrapods' (OntoTransEvol) targeting Seventh Framework.

assistant: **Abstract**

A central goal in evolutionary biology is to understand the molecular changes responsible for phenotypic differences between species, in particular those that have arisen among mammals. Phenotypic evolution is thought to be largely founded on developmental gene regulatory changes, which determine species-specific tissue morphologies and thus lay the foundation for their typical physiological properties. We recently performed the first cross-mammalian transcriptome comparisons for adult organs, providing many insights into the molecular evolution of organ physiologies, but the evolution of developmental transcriptomes remains largely unstudied. I propose to generate comprehensive RNA sequencing data for a collection of adult tissues and developmental precursors from many mammals and tetrapod outgroup species (birds, reptiles, amphibians). The data will include dense ontogenetic time courses for key reference species, covering embryonic stages and, for mammals, placental tissues. We will identify coding and noncoding genes constituting core ancestral tissue transcriptomes and assess relative contributions of gene expression changes and the emergence of new genes to the evolution of phenotypically relevant expression patterns. We will also empirically evaluate global models of evolutionary conservation patterns during embryogenesis and placentation. To understand the dynamics of functional and regulatory interactions of different gene types and their evolutionary relevance, we will reconstruct evolutionary transcription networks and assess associated regulatory mechanisms. Overall, this inter-disciplinary “evo-devo” project will unveil ontogenetic and adult gene expression programs underlying shared (ancestral) and lineage-specific morphological and physiological phenotype
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Non-traditional stable isotopes to track the impact of methane in Earth history' (NTSITIMEH).

assistant: **Concept**

Over geological times, the evolution of carbon isotope compositions of carbonates (δ13Ccarb) in sedimentary record highlights many positive isotopic excursions (CIEs), reflecting significant perturbations of the carbon cycle in Earth surface environments. Although generally interpreted as a consequence of an increase of organic carbon burial in sediments, the lack of high organic carbon content, as well as the strong spatial and temporal variability, observed in many sedimentary successions recording CIEs challenge this postulate. Among other alternative hypothesis involving regional or local control, the potential influence of methanogenesis, i.e. the biological process of anaerobic organic matter degradation producing methane (CH4), has been raised; its ability to generate similar isotopic signatures has been demonstrated in modern analogue. Although the processes behind CIEs are questioned, providing more information about methanogenesis impact is challenging based on traditional isotopic tool like δ13Ccarb, as its isotopic effect on is similar to that of organic carbon burial increase. Recently, stable isotope compositions of metals used as enzymatic cofactors of CH4-related processes were investigated to explore their potential as biomarkers of methanogenesis. During the last decade, significant advances have been made on using Ni isotopes as tracers of methanogenesis but important challenges remain to better constrains both their potential and limit. In order to improve our understanding of CH4 cycle and its impact on Earth’s surface environments through geological times, we will investigate further the potential of Ni isotopes and its potential couplings with traditional stable isotope in various modern settings and past environments to enhance our ability to tra
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Gas-Only internal combustion engines' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

In order to realize sustainable mobility in Europe, both urban and long distance vehicles for road transport will have to be significantly more efficient by 2020+ and a considerable contribution will have to come from the energy efficiency improvement of the powertrain.  Moreover, together with the progressive efficiency increase coming from the engine technology evolution, the use of Low-Carbon Alternative Fuels, such as Natural Gas, will play a fundamental role to accelerate the process of decarbonization of the transportation sector that in Europe is targeted for the 2050 time horizon. In this context, being well-known the benefits of the Natural Gas Vehicles adoption in Europe, this proposal aims to exploit the main benefits of gas-powered engines developing CNG-only, mono-fuel-engines able to comply with:• post Euro 6 noxious emissions• 2020+ CO2 emissions targets• new homologation cycle and Real Driving conditions and simultaneously improving engine efficiency and vehicle performance also with regard to its CNG range capability. These engines, based on new combustion processes, require also dedicated technological solutions for:• Innovative injection, ignition and boosting system concepts• Advanced exhaust gas aftertreatment system • Detecting the gas-quality and its compositionThe results obtained from the experimental activities on the demonstration vehicles and engines will be harmonized and analysed throughout a final overall assessment of the different approaches. The demonstrator vehicles will be assessed in terms of performance and emissions with regard to NEDC, WLTP and under real driving conditions. Moreover, the final assessment of the vehicles will be certified, as “independent testing”,  by JRC (Joint Research Centre) which will carry out additional me
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'New Material Hybrids With Helical Inner Architecture: Fundamentals And Technology' (HybridMat).

assistant: **Concept**

A new approach to design and manufacture hybrid materials based on biomimetic principles is proposed. The internal structure of multi-component metal hybrids will be created simultaneously at two levels: nanostructuring each constituent while also architecturing helical macroscale features. This project aims on fundamental study of physical mechanisms triggered by simultaneous mixing and nanostructuring of immiscible metals by severe shear while producing new types of hybrid materials. Severe Plastic Deformation (SPD) with rotating shear plane and variable inclination angle will be used for production of multicomponent materials to obtain properties not found in individual conventional materials. This will be achieved by ‘architecturing’ the inner structure of the hybrid with consideration of the interface bond and enhanced inter-diffusion under SPD. A model of a hybrid consisting of different constituents with intercalated boundary layers will be developed. A thrust of research is primarily directed at the barely investigated shape and length scale effects of the constituents on the resulting properties of the new material.For practical applications, it addresses the nanostructured high-strength electrical conductor cables for efficient energy transmission. The project assists in developing novel manufacturing technologies for niche applications.


**Keywords:** Hybrid materials, Biomimetic, Nanostructuring, Metal hybrids
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Redefine energy Efficiency solutions for hydrogen powered SHIPs in marine and inland waterway'.

assistant: **Innovation**

Under the framework of Zero Emission Waterborne Transport (ZEWT), hydrogen as the future fuel for ships offers an opportunity to zero the GHG emission. Nevertheless, the challenges for onboard hydrogen storage and utilisation obstruct this long desired revolution. Novel and effective technology solution is urgently needed. The project, RESHIP, aims to redefine the onboard energy saving solutions for newbuilds and retrofits in marine and inland waterway with disruptive technologies in two distinct areas, Energy Saving Devices (ESDs) and onboard hydrogen utilisation. Regarding the ESDs, the project proposes to research and develop hydrogen compatible ESD solutions in standalone/combined applications, centered around Tubercle Assisted Propulsors (TAPs), to improve the vessel's propulsive energy efficiency and to optimise towards hydrogen power and drive system. With the novel and energy efficient hydrogen carrier technology HydroSil, RESHIP links the ESD technology to the research of the energy efficient onboard hydrogen utilisation technology to systematically reshape the hydrogen driven ships with a holistic energy saving solution. Together, RESHIP aims to achieve a minimum overall 35% energy saving and to half the hydrogen storage demands on space and/or weight, comparing to the state-of-the-art hydrogen powered vessels.The proposal responds to the Horizon Europe Research and Innovation Action call on the topic “Innovative on-board energy saving solutions” (ID: HORIZON-CL5-2021-D5-01-10). The consortium gathers world-leading multidisciplinary experts and key patent holders with 13 partners from 9 EU countries, forging a complementary stakeholder group. The consortium covers two industrial sectors, shipping and ships together with hydrogen. The implementation of the deve
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'HOLOCENTRIC CHROMOSOME EVOLUTION AND THE ORIGINS OF BIODIVERSITY IN A HYPER-DIVERSE PLANT LINEAGE' (HoloChromEvol) under Seventh Framework.

assistant: **Objectives**

Holocentric chromosomes are commonly referred to as having a diffuse centromere. Holocentric chromosome organization has been described for three of the six supergroups in the domain Eukarya (the Eukaryotes): plants (angiosperms, algae and mosses), animals (numerous arthropod clades, velvet worms, and nematodes), and Rhizaria.It has long been recognized that chromosome fragments that would be lost in monocentric chromosomes may be propagated and become fixed in organisms with holocentric chromosomes. In addition to fission and fusion, which may be only weakly underdominant or nearly neutral in holocentric chromosomes, holocentric chromosome structure facilitates translocations and inversions.In the sedge genus Carex (Cyperaceae), 2n = 12 – 124, chromosome rearrangements contribute to genetic diversity within species. These findings suggest that holocentry is an important determinant of biodiversity patterns in the wide range of lineages in which it occurs. Holocentry undoubtedly also plays an important role in the evolution of recombination rates which may be selected by the environment. There is another dimension to chromosome evolution in organisms with holocentric chromosomes: Chromosome rearrangements may suppress recombination (islands of speciation theory).The goals of this study are to answer four fundamental questions: 1) Do chromosome rearrangements protect ecologically significant genome regions from recombination? 2) To what extent do chromosome rearrangements decrease the fitness of first- and second-generation interpopulation crosses? 3) What are the relative contributions of hybrid dysfunction (decreased fitness of hybrids between individuals with differing chromosome numbers) and recombination suppression to chromosomal speciation? and 4) Do the populatio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'European Working Group on Genetics of Hearing Impairment'.

assistant: **Objectives**

The aims are to co-ordinate research on genetic deafness and establish research and clinical data banks, combining clinical in-depth family and phenotypic studies with basic molecular genetic and gene mapping methods.The loss of hearing results in social isolation and it imposes a severe economic and social burden on those affected. Hereditary factors account for a large portion not only of congenital and early onset deafness, but also of progressive bilateral hearing loss. Identification of probands having similar phenotype is difficult because many genes are involved and different mutations can cause similar phenotypes. Progress in this field are also difficult for paucity of clinical criteria and the vagueness of definitions used by the different professionals involveded. Genetic heterogeneity among subjects greatly complicates the task of mapping genes by linkage analysis; therefore it is essential to have families which have been meticulously characterised clinically. For syndromal hearing loss, the main obstacle to obtain a homogeneous series of families is the difficulty to find a sufficiently large number of subjects affected by the same disorder, since usually, these conditions are rare. For non-syndromal hearing loss, the research strategy must be designed to accomodate genetic heterogeneity, and careful clinical documentation, using uniform protocols and definitions, distinguishing subgroups. Extensive collaboration is usually necessary. This project is carried out dividing centres members into study subgroups, which although interactive and in connection with one another, have the task of developing a particular line of research. The subgroups are: 1) Study group on terminology, definitions and hearing assessment, 2) Study group on epidemiology of genetic he