RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Tools And Practices For Business Cycle Analysis In National Statistical Institutes Of EU' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

The objective of this project is to propose a unified statistical analysis of business cycles in European national statistical offices.Our aims are to:(1) review and evaluate the main techniques available;(2) survey the practitioners needs and practices;(3) customize the most satisfying techniques in order to match the practitioners requirements;(4) organize the different steps of a typical analysis, making available a range of algorithms at all steps;(5) implement the overall scheme in a prototype software;(6) and to disseminate the software tool.Emphasis will be put on statistical properties, on method reliability, and on how suited is every method to the case of European economies and to the data typically available in NSI's. The investigation will balance theoretical and practical considerations, fundamental analysis and empirical experience.Objectives:The objective of the project is to review, evaluate, and customize advanced statistical techniques for business cycle analysis and to make them available for routine use in NSI. The final aim is to implement a software tool able to guide official statisticians through the main steps of a standard business cycle analysis, in an organized and informative way, so as to help in improving the knowledge of cycles in EU economies.Work description:Since our aim is to ease the practice of business cycle analysis in official statistics, a careful reviewing of the main techniques, evaluating their performances and comparing their advantages and drawbacks is a necessary first step. That review must also include practical considerations, with an exhaustive description of the practitioner uses and constraints. It will then be possible to work out a set of candidate approaches that could be followed by European official statistician
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'SARS-coV2 variants Evaluation in pRegnancy and paeDIatrics cohorts', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Variants of concern (VoC) of SARS-CoV-2 raise the possibility of increases in transmissibility, severity and immune evasion. Children and pregnant women who have not been prioritised in the pandemic, are likely to be the last population for whom vaccines are approved and may have low uptake, increasing the risk of VoC arising in this population. Monitoring this group across regions is crucial given rapid changes in epidemiology due to interventions, vaccine rollout and viral evolution. VERDI (SARS-CoV-2 variants Evaluation in pRegnancy and paeDIatrics cohorts) will build on a long-standing infectious disease research and trial network (Penta) to address research questions on the impact of VoC in these vulnerable groups.Mpox virus (known as monkeypox or MPX, when this application was originally written) is a zoonotic Orthopox virus first described in the Democratic Republic of Congo (DRC) in 1970. It is an infection of global significance, with cases reported in 11 African countries and sporadic cases reported outside Africa as a result of zoonotic transmission and travellers returning from endemic areas. However, despite the global burden of mpox disease, research into mpox has historically been neglected. This current outbreak of mpox is, like many communicable and non-communicable diseases, a complex biosocial phenomenon, disproportionately impacting marginalised communities, whilst exposing and amplifying global health inequities.Since May 2022, large numbers of mpox cases have been reported in non-endemic countries. As of 9 September 2022, there have been 57,527 confirmed cases of mpox since the start of the 2022 outbreak, with the vast majority being reported in non-endemic countries. Of the 103 countries reporting cases in this current outbreak, 96 are countries w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Training the next generation of experts in knowledge-based design PRinciples Of induStrial-scale PhotorEactoRs', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

PROSPER's overarching outcome will be the availability of knowledge-based design guidelines for industrial-relevant application cases, together with strategies for scale-up and a safe long-term operation, ultimately leading to the broad application of photochemistry on an industrial scale. PROSPER will setup a tailored network to train the next generation of experts on fundamentals, design principles and application of industrial-scale photoreactors through comprehensive education on a broad portfolio of topics related to photochemical processes and through hands-on training on industrially relevant research topics. By this, the industrial and academic partners of PROSPER will overcome implementation hurdles and enable the chemical industries’ transition towards sustainable production. The main scientific objectives are:1.to develop standardized methods for measuring the photon flux and characterizing radiation fields,2.to understand the impact of mass and heat transport effects on the performance of photoreactors as a basis for developing novel industrial photoreactors for sustainable processing and process intensification,3.to establish reaction control strategies which maximize photon use efficiency and enable long-term operation,4.to elucidate safety requirements for photochemical processes and5.to develop a knowledge-base on photochemical reactor and processes development, containing design guidelines and principles together with performance criteria for photoreactors to enable a knowledge-driven development and scale-up, eventually leading to standard reactor designs.Joint interdisciplinary research by academic and industrial partners will be realized by excellent training through a high-quality, cross-sectional research network including 6 internationally reputed
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Developpment of the complete ERTMS concept' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

The project is a part of a set of interlinked activities aimed at the development of a European wide common concept for a railway safe signalling system (ERTMS). In particular, the project coversthe main industrial activities relating to the system design and prototyping.This includes those activities aimed at :1. To define an overall ERTMS System concept and system architecture.2. To extend and consolidate the subsystems and interface specifications on the basis of the outlined system architecture.3. To elaborate a common framework of technical tests, including specification of test scope, test procedures and test tools. This includes, in particular the 'specification for the functional and interoperability tests to be carried out in the Madrid-Seville High-Speed Line '(ERTMS-EMSET project)4. To develop a set of common test tools for laboratory and on-site testing.5. To demonstrate the technical feasibility of the ERTMS System concept, including main critical subsystems, based on the laboratory and simulator tests.6. To establish a common approach for the assessment of system safety.7. To complete the technical ERTMS specification on the basis of EEIG users functional and system requirements. %To fulfill the interoperability requirements for the high-speed European rail network.Creation of a set of common interoperability and technical specifications to be used as a European kernel for input towards standardisation activities.Demonstration sites on SNCF, DB, FS" networks + Madrid-Seville High-Speed line %Directive 91/440 - "The development of Community Railways" / Directive on the Interoperability of High-Speed Train Networks"
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Mining Sandboxes for Automatic App Protection' to be submitted under Horizon 2020.

assistant: **Abstract**

Today’s industry is more vulnerable to cyberattacks than ever. The biggest threat comes from advancedpersistent threats that targets the sensitive data of a specific company. Such a threat may come along asan innocuous app that starts its malicious behavior only when the mobile logs into the corporate network.At the same time, such threats can be made undetectable through testing or code analysis.The ERC SPECMATE project has developed a technology named BOXMATE that protects against unexpectedchanges of app behavior and thus drastically reduces the attack surface of mobile applications.The key idea is to mine app behavior by executing generated tests, systematically exploring the program’saccesses to sensitive data. During production, the app then is placed in a sandbox, which prohibitsaccesses not seen during testing.This combination of test generation and sandboxing effectively protects against advanced persistentthreats. To access sensitive data during production, the app already must do so during testing—wheretracing makes it easy to discover and assess. BOXMATE neither does not need to collect user data: Allapp behavior is assessed during testing already. Finally, BOXMATE requires no knowledge about sourceor binary code, and thus easily handles arbitrarily obfuscated or obscure third-party apps. BOXMATE iscurrently being patented worldwide.We want to turn the BOXMATE approach into a full mobile security solution for corporate and endusers. This proposal aims at producing a full-fledged prototype that can be demonstrated to potentialcustomers, most notably app vendors and mobile infrastructure providers; as well as developing anadequate marketing strategy exploring and responding to the needs of the market.This proposal is fueled by the principal investigator, Andre
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'European Conference on Mathematical and Theoretical Biology 2005'.

assistant: **Concept**

The European Conference on Mathematical and Theoretical Biology (ECMTB05) is the main international event for the mathematical and theoretical biology community in the year 2005. ECMTB05 is organized by the Center for High Performance Computing in Dresden and will be held at Dresden University of Technology (Germany), July 18-22, 2005. The event is supported by the European Society for Mathematical and Theoretical Biology (ESMTB) and the Society for Mathematical Biology (SMB). ECMTB05 is the sixth tri-annua l conference of ESMTB and is devoted to one of the fastest growing domains in science where experimental biology and medicine, biochemistry, mathematics, computer science, physics and various fields of technology merge. The conference has two objectives, ( 1) to communicate the best of recent advances in mathematical modelling approaches in the life sciences and to identify key targets of future work and (2) to provide a platform for young researchers. (1) is ensured by the expertise of the scientific board and world leading keynote speakers representing 10 hot topics: cellular biophysics, regulatory networks, development, neural systems and the brain, evolution and ecology, immune systems, biomedical applications, biotechnology, innovative mathematical metho ds, inter-disciplinary education. ECMTB05 will attract over 600 scientists worldwide with more than 150 young researchers and more than 50 researchers from East-European countries. Towards objective (2), most young researchers will give talks in mini-sympo sia or parallel sessions and present posters. A special mentoring programme will initiate contacts between young researchers and experts. One day of introductory lectures (July 17, 2005) enables newcomers to optimally benefit from the event. Communication shal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Tracing the evolution of sensory cell types in animal diversity: multidisciplinary training in 3D cellular reconstruction, multimodal data analysis and science outreach.'.

assistant: **Concept**

All animals need to sense their environments. The ability to detect light, temperature, chemicals, sound, vibrations and other stimuli depends on an extraordinary range of sensory cell types. The diversity and relationships between these receptor cells across the animal phyla, the ways in which they have been adapted, reused, tweaked and sometimes lost, is little known, but is crucial for understanding how animals survive and thrive in diverse environments. Most sensory cells are characterised by complex shapes and molecular machinery, first discovered by meticulous electron microscopy in the past decades. More recently, this has been complemented by genetic studies of their development and differentiation in various animal models. These two research programmes have, however, largely remained separate, and a unified morphological and molecular understanding of how the diversity of animal sensory cells has evolved is lacking. Our aim in ZooCELL is to create a comprehensive view of sensory cell type evolution based on the discovery of recurrent patterns of genetic and subcellular structure across a wide range of new animal models. To this end, we will combine single-cell genomics, correlative light and electron microscopy, Artificial Intelligence, and reverse genetics approaches in these species. ZooCELL will bring together Europe’s world-leading expertise in these disciplines, and thus contribute to building the field of comparative integrative cell biology in animals. While training the next generation of doctoral students in these novel interdisciplinary techniques, we will develop new tools for combined molecular and morphological comparative analyses of cell types. Our interdisciplinary, intersectoral and international training programme will also include disseminati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Integrating SENSorimotor disorders with ankle hyper-resistance in cerebral palsy' in the context of a Horizon 2020 call.

assistant: **Objectives**

Walking requires interactions among a central unit (motor system), actuators (musculoskeletal system) and real-time feedback (sensory system). When a brain lesion occurred, such as in cerebral palsy (CP), this is reflected to these systems. With this proposal, I aim to understand how the impaired system interaction affect walk ability. CP is the most predominant childhood disability. This disability is generally defined mainly as motor impairment, but it is known to be associated with somatosensory disorders. The sensory system is composed by sensation and perception. Here the perception will be assessed as cortical proprioceptive processing using MEG. The motor system will be analysed at the spinal level and in terms of resistance to passive ankle movement (neural and non-neural components of spasticity), whilst the lower limb musculoskeletal properties are quantified as morphology, stiffness and composition. I will focus on three objectives: (1) to unveil the interaction between spasticity and cortical proprioceptive processing, (2) to establish methodologies for extracting lower limb musculoskeletal properties and associate them with gait ability; (3) to understand whether is possible to delineate a statistical model that describes how altered motor, musculoskeletal and sensory systems at the ankle joint level affect gait ability. I will quantitatively analyse CP as sensorimotor disorder, thus opening new scientific and clinical frontiers.To successfully perform this project, I established a cooperation between myself and experts in musculoskeletal (my supervisor Prof. Taija Finni) and sensorimotor (Assoc.Prof. Harri Piitulainen) systems at the host institution. Their knowledge, their research teams and the facilities available will allow me to perform the planned st
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Regulation of ventral otic patterning and integration with general programmes of neurogenesis in the zebrafish embryo' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Both during my diploma and my PhD project, neural development has been a focus of my research interest. During my PhD thesis I have worked with the role of signalling pathways on the specification and patterning of the caudal neural tube and during early olfactory development mostly using an in vitro system. Now I would like to change focus and a future challenge lies in understanding the molecular interactions that underlie animal development. The proposed work together with Tanya Whitfield at the MRC Centre for Developmental and Biomedical Genetics (CDBG) in the Department of Biomedical Science, University of Sheffield would enable me to take a new, genetics based approach to questions that have fascinated me for a long time and increase my experience with in vivo studies.The otic placode gives rise to non-sensory, sensory and neural structures of the inner ear. Early during development, neural and non-neural regions form in the otic epithelium and both the first sensory hair cells and the neurons of the statoacoustic ganglion arise from ventral regions. Work from the Whitfield lab has implicated Eya1/Six1, Tbx1 and Otx1 in regulating neural versus non-neural patterning of the zebrafish ventral otic epithelium, but how these factors interact to regulate sensory patch spacing, and integrate with general programmes of neurogenesis, is not understood. I plan to elucidate in detail the genetic network responsible for ventral otic patterning. In a first step I plan to characterize the system through the analysis of the expression patterns of patterning (eya1/six1/tbx1/otx1) genes, neural progenitor soxB1 genes and markers for sensory neurons and hair cells in wild-type and mutant zebrafish lines.  In parallel, I will start to test the model that Tbx1 and Otx1 restrict neur
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Assembling the Cosmic Puzzle: Theoretical Insights into the Detectability of Molecular Isomers in Space'.

assistant: **Innovation**

The advent of modern space instruments and ground based radio telescopes for ice and gas-phase molecular detections has brought astrochemistry into a golden age. In just the last five years, more than 30% of all known interstellar molecules have been detected—a staggering figure for a field with a history of several decades. Along with the numbers, the chemical complexity has also grown to complex organics and aromatic molecules. However, this rapid expansion presents critical challenges for understanding interstellar chemical complexity. The most pressing of these is the increasing number of detected isomers, molecules that share the same molecular formula but differ in their structure. Predicting their abundance in the interstellar medium, a highly non-equilibrium environment, is particularly important for the interpretation of molecular inventories derived from radio astronomy.The project ISOCOSMOS aims to tackle interstellar isomerism from a theoretical approach closely connected with observations. Building on my previous experience in machine learning, ab-initio calculations, and kinetic models, I aim to predict, explain, and leverage isomeric ratios in astrophysical environments. In particular ISOCOSMOS will explore the largest laboratory in the Universe, the Taurus Molecular Cloud. ISOCOSMOS will lift current limitations in the interpretation of astrochemical observations and pave the way for a new era, guiding future discoveries and establishing better constraints on the molecular inventory of the interstellar medium, and will contribute to understand the role of isomerism in the emergence of complex, possibly prebiotic, interstellar molecules. With its interdisciplinary approach, the tools and databases developed by ISOCOSMOS will support advancements in other