RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'TURN ON THE LIGHT ON SCIENCE' to be submitted under Seventh Framework.

assistant: **Abstract**

Light’10 is  conceived as a “cultural change event” that bridges the gap between the researchers involved in contemporary research and the people who will ultimately benefit from it.Using hands-on activities, demonstrations, dialogue with researchers and a general sense of festivity, Light’10 brings visitors on a fantastic tour into today’s science and technology practical uses and theoretical bases. While targeting the general public Light’10 will also be promoted within high schools,  universities  so to ensure a larger participations of the 16-24 years old age group with a view to change the image of science and scientists within future human resources potential.Light’10 will focus on a fascinating theme: “Science Fiction becomes Science Reality”. Light’10 aims to show that the future, as proposed by the science fiction in advertising, books and movies, is continuously shaping our daily existence.The location will be the  Rome Planetarium which is per se a fascinating and friendly scientific environment. Light’10 will take place in Rome, the capital of the country,  but it is not  a “local” event with “local researchers” and “local” research labs  involved in the activities with the public. Light’10 makes scientists from all over Italy converge on Rome. The event will last from 5 pm till midnight.Light’10 is organised around the following events:-The “Hands on workshops” within which people will interact with researchers, make experiments, listen to friendly explicative speeches-The “Globe Science Theatre” event space where researchers who take  part in performing and visual  arts will  entertain the public.-The Planetarium and astronomical museum, where visitors will be enchanted by the show with live lectures on stars and planets and the spectacular astronomical mu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'EBRAINS 2.0: A Research Infrastructure to Advance Neuroscience and Brain Health'.

assistant: **Innovation**

EBRAINS is a collaborative European Research Infrastructure designed to advance and accelerate progress in neuroscience and brain health. This innovative infrastructure, a legacy of the Human Brain Project (HBP), is an ecosystem where researchers, clinicians and experts from various disciplines converge to explore and analyze brain complexity – from molecular and cellular levels to the functioning of the entire organ. Therefore, the project aims to create a new standard for brain atlases from the micro- to the macro-scale, link foundational multi-level data and connectomes in the healthy and pathological brain with atlases and models, create digital twins through modelling and simulation as well as unique, excellent, and preferred services for FAIR neuroscience data. The overarching goal of EBRAINS 2.0 is to foster a deeper understanding of brain structure and function with dedicated and mature software tools, to facilitate the development of more effective treatments, new drugs, diagnostics and preventive measures for neuro-psychiatric disorders. We expect that EBRAINS 2.0 catalyzes progress in the field of large-scale models running on HPC towards Exascale and leads to innovative solutions for neuro-inspired computing, and cognitive technologies such as neurorobotics and AI. Sophisticated digital modeling and data analytics capabilities will benefit communities beyond neuroscience, such as biomedicine. We will advance EBRAINS technology, platform services and the base infrastructure roadmap, educate and train a new community of users and developers from academia, industry and SMEs, and ensure knowledge transfer. EBRAINS 2.0 will become the neuroscience hub in the European infrastructure landscape, through building strong links with the European data spaces, EOSC and E
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Quantum cohomology and equivariant floer cohomology of the loop space' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Givental has conjectured, that the U(1)-equivariant Floer cohomology of the universal covering of the loop space, of asymplectic manifold, should have the structure of a D-module, over the Heisenberg algebra of first order differential operators on a complex torus and that this should be the same as the quantum cohomology D-module of the manifold. I intent to study this conjectured equality and its implications in computing the quantum D-module. This implies also computation of the quantum ring, as the later is the semi-classical limit of the former. There are three concrete directions of research. First, note that there is a Fourier transform" of equivariant cycles that transforms relations in the D-module to differential operators. If we could compute this transform, then we could compute the D-module. Because of the infinite dimensionality of the loop space though, there are problems with computing the integral involved I have managed to compute it in the case of positive toric manifolds, but this method relies on the Fourier expansion and doesn't seem to generalize to non-toric manifolds. For the case of general semi-positive symplectic manifolds, I propose A totally different method, which relies on using localization techniques and a certain exact sequence arising from Morse theory of the simplistic action functional, in order to regularize the ratios of relevant equivariant Euler classes. The second program I propose, is to use the model of Getzler, Jones and Petrack, for the equivariant cohomology of the loop space. They identify it with a version of the cyclic bar complex, involving Connes's operator B and this could be used to compute the relevant "Fourier transform". Thirdly, I intent to investigate applications of these, to Kontsevich's homological mirror sy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Innovative Enterprise Financing Ideas from Europe conference'.

assistant: **Concept**

Main objective of this action is to have staged an event that has, through a clear communication strategy, raised awareness of the opportunities for financing research, innovation and entrepreneurship. To have strengthened existing and built new networks contributing to an effective dissemination of information continuing after the event.


**Keywords:** Access to Risk Finance, Innovative Enterprise, Conference, Presidency
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Exposure to low levels of benzene, interindividual biologicalvariability and cancer risk: a multicentre European study'.

assistant: **Innovation**

Benzene is a ubiquitous pollutant, to which people are exposed from both occupational and environmental sources These include a number of industrial processes, exposure to gasoline, cigarette smoking, automobile exhaust, and others Benzene is a human carcinogen which has been specifically associated with leukemia in several populations with high occupational exposures. There are many uncertainties related to benzene exposure, health effects and mechanisms. This especially applies to situations of low exposure levels (<10 ppm) which are quite common in modern Europe, and for which very little of information is available. This project involves the study of a number of cohorts of European workers exposed to low levels of benzene The cohorts include petrochemical workers from Bulgaria, Italy and Great Britain, filling station attendants and traffic wardens from Genoa and Milan in Italy, and bus drivers from Genoa. The range of benzene exposures in these cohorts is from 0.01 to 10 ppm, and the total number of workers is in excess of 80,000. Information is available for these cohorts on occupational history, smoking history, occupational hygiene data including ambient air monitoring, and in some cases blood benzene levels. A cross-sectional study will be conducted on samples of actively employed workers from each of the cohorts to be studied in the project, with controls chosen from suitable non-exposed populations. Biomarkers will be employed along with benzene air measurements to precisely characterize individual exposure levels. The biomarkers to be used include trans,trans-muconic acid as a marker of internal dose; benzene oxide-hemoglobin-S-phenylcysteine adducts as a marker of biologically effective dose; and differential white blood cell count, and single strand breaks
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Organic-Ferromagnetic hybrid interfaces for Spintronic applications'.

assistant: **Innovation**

To ensure the long-term advancement of information technology, radically new concepts, materials and processing methods are required to circumvent the fundamental limitations of traditional, silicon-based electronics. One of the most promising approaches is to explicitly exploit the spin of charge carriers in spin electronics, or spintronics. In this rapidly expanding field, there is a strong need for the development of novel, multifunctional materials and (hybrid) heterostructures with desirable magnetic and transport properties. Organic semiconductors, which form the basis of the by now well established field of organic electronics, are especially promising for spintronics applications, not in the least due to the low spin-scattering amplitudes attainable in these materials.As we learned from the development of organic electronics, understanding and tuning the properties of hybrid inorganic-organic interfaces is of fundamental importance for the optimisation of device performance and stability. OFS PIN specifically aims at the development of new knowledge in the field of organic-inorganic based multifunctional materials combining unusual magnetic, electric and optical properties. This proposal is strongly motivated by the recent results obtained in the field of Organic Spintronics, were the pioneering role of Europe was established by two of the presenting partners in OFSPIN. The project will build the knowledge foundations necessary for the development of an interdisciplinary technology based on novel organic and inorganic functional materials, that will evolve into a sustainable technological platform for spintronics and quantum computing.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Radical Innovation Maskless Nanolithography' (RIMANA).

assistant: **Concept**

The STREP proposal Radical Innovation Maskless Nanolithography (RIMANA) aims to research and develop a key maskless nano-patterning technology for low to medium volume production, essential for the semiconductor industry and emerging nanotechnology industry.RIMANA is driven by two global industrial needs:- An ML2 tool for short run and low to medium volume leading edge device manufacturers (Logic, ASIC, Silicon Foundries)- A fast Mask Writer for the leading edge high volume device manufacturers (MPU, DRAM, Logic)Both global industrial needs are addressed by the proposed RIMANA project with the following overall S/T objectives and work plans:- Concept and realisation of a new, highly innovative compact APS (Programmable Aperture Plate System), including high-speed electronics with the ability to generate a massive parallelisation of electron beams for the 32nm technology node and beyond- Concept and realization of Data Path improvements to achieve higher data rates- Design and generation of test benches to demonstrate sub-32nm node ML2 high throughput capabilities in resist- Brainstorm of results with perspectives for potential industrial realisationThe key challenges will be to explore and develop essential elements for the massive parallelisation of electron-beams and electron-optics, retaining ultimate resolution down to the nanometre scale, while minimising throughput-resolution trade-offs.The project will be carried out by a strong and diversified team from industry, academia and acclaimed European research institutes, under the leadership of IMS Nano-fabrication GmbH, an SME with extensive experience in cutting-edge charged particle nano-fabrication research and technology.RIMANA is harmonised completely with the FP6 strategic objective IST NMP-3. In particular, RI
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Tagging of rice genes for use in cereals (CEREALGENE TAGS)' in the context of a Fifth Framework call.

assistant: **Objectives**

Human nutrition is based on cereals, where Rice is the model because of its small genome, detailed molecular maps and ease of transformation. We aim to use functional genomics and proteomics in rice for which a rough draft of the genome sequence is available. The integrated strategy proposed here will provide a phenotypic function to the rice gene sequence information in the databases and address traits of interest for cereal crops. We will use a Rice Mutation Machine to uncover gene-phenotype relationships using knockout or gene detection transposon inserts and Proteomics methods to discover novel transcription factor networks determining key cereal traits. Cereal crop validation will be done using gene over expression and map correlations to known traits. The gene-trait discoveries will provide applications and intellectual property using GMO as well as non-GMO strategies for cereal crops in the EU.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Coherent sources and micromachining for imaging, wireless communications, and sensing at terahertz frequencies' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Exciting opportunities at terahertz (THz) frequencies are emerging in science and engineering. Striking images of tooth decay or skin cancer have been obtained with biomedical THz imaging, and the nonionizing nature of THz radiation eliminates the issues that are commonly associated with X-rays and radioactivity. In addition, many molecules have distinct signatures at THz frequencies, so changes in composition are easily detected.Impressive results from DNA molecules with minute changes suggest that very selective interactions occur at THz frequencies and point to applications in gene sequencing. THz communication channels can provide an intersatellite link or, in picocells of digital wireless networks, the terminal link from a fiber-optical network at Tbit/sec to the end-user at several 10 Gbit/sec. Compact antennas emit narrow beams without the alignment issue associated with infrared lasers or wide beams for area coverage.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Conditioning regimens shape the homeostasis of adoptively transferred T cells: Effects on autoreactivity and role in anti-tumor therapy' to be submitted under Seventh Framework.

assistant: **Abstract**

The ability of adoptively-transferred T cells to mediate an immune response is modulated by the host environment. It has previously been shown that donor T cells proliferate and acquire memory-like characteristics when injected into lymphopenic hosts while in hosts with a « full » T cell compartment, they remain naïve and do not acquire effector function. As it is important to optimize the persistence and responsiveness of transferred T cells for immunotherapy strategies, we assessed whether T cell fate is dependent upon the conditioning regimen used to achieve lymphopenia. We induced lymphopenia in C57Bl/6 mice by sub-lethal irradiation or chemotherapy using busulfan with cyclophosphamide (Bu/Cy) and found that the relative engraftment of CD4 and CD8 T cells was markedly changed by the conditioning protocol: Irradiation-induced lymphopenia resulted in a skewed proliferation of donor CD8 T cells with a CD4:CD8 ratio of <1:5 whereas Bu/Cy-induced lymphopenia resulted in a massive proliferation of donor CD4 T cells with only minimal proliferation of CD8 T cells. These results clearly demonstrate that lymphopenic conditions are not equivalent in their potential to foster the regeneration of T cell pools. I propose to study the characteristics of the host and adoptively-transferred T cells generated in these two lymphopenic environments, with specific assessment of TH1, TH17 and Treg subsets. As the host microenvironment modulates T cell persistence and function, the effects of these regimens on the fate of stromal cell and APC populations will also be monitored. Moreover, I will study the consequences of irradiation and Bu/Cy conditioning on the reconstitution and function of adoptively-transferred T cells harboring a re-directed tumor-specific TCR in mice harbouring B cel
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Integrated Cicuit Testing Software' (TEST-IC) under Horizon 2020.

assistant: **Objectives**

The project is in the semiconductor testing software field.In the semiconductors testing process, nowadays most of the test programs are implemented manually combining vector sequences generated by automated tools (ATPG, automated test pattern generator). This implementation embeds the possibility of human errors, which can cause yield loss (“over-testing”), or quality (test escape, “under-testing”) problems.In our innovation:- the requirement and test specification, the test program implementation and verification are based on formal modeling.- Ad-hoc traceability algorithms have been identified and experimented. - Advanced data analysis techniques are applied - Correlation techniques are implemented to forecast device reliability.Europe has a strong share in the semiconductor market (STMicroelectronics, Infineon and NXP, already customers of ours). One of the more important global challenge is the development of new testing technologies and approach that lives up to the growing rate and complexities of the semiconductor industry.The industrial user needs addressed by our innovation are:.- Reduction of test escapes- Reduction of the development effort of test programs - Controlled and documented test development process.Technical/industrial feasibility objectives- Study for the adaptation of the SME’s existing industrial capability to the production of the final product and processes optimization, gap analysis and costs quantification - Due diligence on regulatory requirements- Plan for intellectual Property (IP) management.Economic Feasibility objectives:- Market study and definition of the marketing approach, - Economic risk assessment.- Analysis of the economic feasibility - Quantification of the capital and investments required - Development of a financial program