RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'SELENE: Self-monitored Dependable platform for High-Performance Safety-Critical Systems' under Horizon 2020.

assistant: **Concept**

Existing HW/SW platforms for safety-critical systems suffer from limited performance and/or from lack flexibility due to building on specific proprietary components, which jeopardize their wide deployment across domains. While some research attempts have been done to overcome some of these limitations, their degree of success has been low due to missing flexibility and extensibility, which would ensure that industry can take that path, as many industries need technologies on which they can rely during decades (e.g. avionics, space, automotive). A number of high-performance computing (HPC) commercial off-the-shelf (COTS) platforms offer the computation capabilities needed by autonomous systems in domains such as automotive, space, avionics, robotics and factory automation by means of multicores, GPUs and other accelerators. Unfortunately, the utilization of HPC platforms has been traditionally considered out of the reach of the safety critical systems industry due to the difficulties or roadblocks these platforms bring to the certification process.   SELENE follows a radically new approach and proposes a Safety-critical Cognitive Computing Platform (CCP) with self-awareness, self-adapting, and autonomous capabilities. SELENE’s CCP uses artificial intelligence (AI) techniques to adapt the system to the particular internal and external (environmental) conditions with the aim of maximizing the efficiency of the system being able at the same time of meeting application requirements. AI techniques are feed with information provided by the on-line monitors and external sensors and are applied in a transparent way without compromising the safety of the system. To ensure safety requirements are preserved SELENE’s CCP relies on the strong isolation capabilities provided at hardwa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for '0S2500/78-Demonstration of a large scale, Second Generation, Off Shore Wind Turbine, complying with new grid requirement' under Fifth Framework.

assistant: **Concept**

The key objective of this project is to demonstrate an innovative wind turbine which is designed specifically for off shore and other applications where penetration levels are likely to be very high. The demonstration turbine will:- Comply with new grid regulations for large wind parks, are presently only in draft form;- Be larger than any commercially available wind turbine (size optimised for offshore applications);- Be suitable for use on weak grids - have an increased minimum maintenance interval compared to its predecessors. A scientific monitoring and evaluation programme will be carried out over a twelve month period confirm that the above objectives have been met.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Integrated approach for a sustainable and healthy freshwater aquaculture' (SUSTAINAQUA).

assistant: **Innovation**

About 75 percent of the world's most valuable marine fish stocks are either fished to the limits or over-fished. At the same time world fish consumption has increased from 45 million tonnes in 1973 to more than 130 million in 2000, with an estimated rising demand in the future. In order to serve this increasing demand on the long run, sustainable alternatives have to be strengthened.The most promising one is the aquaculture industry, dominated by SMEs (90%), providing more than 60.000 jobs in Europe, including upstream and downstream activities. It has undergone a revolution over the last decades and can now be regarded as a significant segment of the EU economy and global fisheries sector. However, disorientation regarding best practices and the need t o be competitive especially against low cost producers from Asia, Latin America and the Caribbean result in an increasing pressure on the aquaculture farms, especially in the case of SMEs. Moreover, several adverse impacts resulting for instance from the discharge of effluents, water extraction, chemicals use or genetic releases are opposed to upcoming restrictive European and national environmental and health legislations and demands.The success of European's aquaculture farmers in the growing global aqua culture market depend in a great measure on farmers' ability to stand the different requirements: to compete with foreign aquaculture products and to respond to European and national political and consumers' quality, environmental and health requirements.Therefore, the overall objective of the proposed project is to expand the knowledge base of the European freshwater aquaculture farmers by training them mainly in following three clusters of innovation:(1) Diversification of economical valuable products,(2) Improving p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Mitochondria, Peroxisomes and Lysosomes - the ""menage a trois"" of cellular metabolism""' to be submitted under Seventh Framework.

assistant: **Abstract**

The metabolic roles of mitochondria, peroxisomes and lysosomes are well established. Numerous genetic defects affecting the function of these organelles result in a wide spectrum of metabolic diseases. The involvement of these organelles in signalling pathways is receiving increasing attention. Furthermore, interactions between them and other cellular components have been elucidated. Evidence is now emerging that dysfunction in mitochondria, peroxisomes or lysosomes causes secondary perturbations in the other two organelles. The fundamental hypothesis presiding to this proposal is that mitochondria, peroxisomes and lysosomes form an interdependent network (MytoPexLyso), which is likely to have fundamental roles in cell biology, metabolism and metabolic diseases.To test this hypothesis and elucidate the role of the MitoPexLyso network in physiology and disease, we will employ state-of-the-art imaging and systems biology approaches. First, we will uncover how dysfunction of each MitoPexLyso organelle affects the network. We will test if mitochondrial dysfunction can trigger lysosome biogenesis, and also systematically address how perturbations in one organelle affect the other two. Second, we will identify signalling pathways sensing perturbations on the MytoPexLyso network, and elucidate their pathologic significance, both in cell lines and in animal models of metabolic diseases. Third, we will test a novel strategy to cure mitochondrial diseases: enhanced removal of damaged mitochondria through increased lysosomal autophagic capacity. We will generate a novel mouse model with higher lysosomal capacity in the skeletal muscle, and use a mouse model of mitochondrial myopathy, to test this premise in vivo.This proposal addresses key questions in cell biology and metabolism,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Smart Complex Emulsions: A Versatile Approach to Opto-Electronics and Sensors'.

assistant: **Innovation**

Dynamically reconfigurable complex emulsions are becoming increasingly important in pharmaceuticals, medical diagnostics, and sensing. The main objective of SMARTDROPS is to develop original Smart Complex Emulsions (SCEs) and unlock their extraordinary multifaceted potential by creating novel integrated devices. In particular, SMARTDROPS will be focused on exploring three potential applications of SCEs: (1) SCEs containing multifunctional liquid crystals to create new dynamically controlled lensing devices, (2) SCEs that can form complex nanostructures, which will be used as high-performance organic electronics devices, wherein the liquid crystal organization will facilitate the charge transport, and (3) SCEs-based sensors that will be incorporated into organs-on-chips for continuous monitoring of cell activity without the need for complex and specialized equipment. Our target materials and their properties are relevant to present and newly emerging technologies, including high-resolution micro-lenses, high-performance OPV/OFET devices, and inexpensive chemical sensors with extraordinary sensitivity and versatility.SMARTDROPS includes a strong transfer of knowledge between the host institution and me. The fellowship will advance my future independent research career in chemistry by providing me an interdisciplinary training in wide-range of skills, mentoring from leading experts in the field, and helping me to develop a new research line that has not yet been investigated at the hosting institution. The results emerging from SMARTDROPS will have a significant impact on the scientific community focused on the preparation of advanced functional materials. The proposed applications may contribute to advance future innovative technologies, and thus special attention will be
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Information Content of locAlisation: fRom classical to qUantum Systems' (ICARUS).

assistant: **Concept**

The aim of this proposal is to study quantum dynamics in the presence of disorder, and specifically the Anderson and many-body localization transition to a phase where transport and thermalization are absent. Localization in quantum systems has both deep fundamental implications in many different fields and exciting practical applications in quantum technology.In this action the researcher, who is experienced in the statistical physics of quantum disordered systems, will address in a novel and timely way this topic. She aims to improve understanding of it with a three-fold approach: a quantum information experimental effort; new theoretical tools coming from the study of random matrices and the physics of glassy systems; and a joint work with a non-academic entity on numerical methods that use artificial neural networks for the classification of the localized phase.She will perform this work in the perfectly suited environment of the Thermodynamics and Energetics of Quantum Systems research group at Trinity College Dublin.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Investigating the emergence of mobile and sedentary pastoralism in Neolithic Iran through ancient food residues analyses and radiocarbon dating'.

assistant: **Concept**

The development of agriculture and the domestication of animals has influenced past human diet up to the modern food industry. Archaeology contributes to enriching our knowledge of past societies, including the exploitation of natural resources by human groups and adaptation to various environments. Human societies associated with the beginnings of agriculture and domestication began in the Neolithic. Recent bioarchaeological studies have highlighted the role of the Zagros mountains (Iran) in the dynamics of plant and animal domestication in the Near East and their spread eastwards. This region has also witnessed the development of nomadic pastoralism throughout its history. Nonetheless, the overall subsistence strategy and beginnings of milk exploitation by these early pastoralists are not yet understood, due to the lack of analysis of absorbed food residue from pottery and difficulties in dating the mobile camps in this area.VARGAH (“mobile camps” in Persian) aims to fill the gaps in our understanding of the development of agriculture and animal management in Iranian archaeology by (1) paleodietary reconstruction, using ancient proteins preserved in human dental calculus and lipid residues preserved in pottery vessels, (2) resolving the chronology using bone collagen dating and compound-specific radiocarbon dating of lipid residues and (3) contextualisation of pastoralism through the comparison of sedentary and mobile groups. This project is based on a synergy between advances in analytical chemistry applied to archaeometry (fellow), cutting-edge expertise in Iranian archaeology and biomolecular geochemistry (host), and advances in 14C geochronology measurements (secondment). VARGAH will provide robust answers on early pastoralism in a region central to our understand
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The Energetics and Habitat of Metabolic Origin' (EcolMetabOrigin).

assistant: **Concept**

Life is a chemical reaction. Over 1000 individual reactions are driven in the direction of cell growth by the coupling of biosyntheses to environmentally available exergonic reactions that are harnessed by a handful of enzymes in energy metabolism. How, where, and from what the chemical reaction of life arose, and how the primordial diversification of metabolism proceeded are the topics of this proposal. Evidence for the process of metabolic origin and traces from the very early course of microbial evolution should be preserved in the chemical reactions of metabolism itself. This concept, traditionally germane to thoughts on biochemical evolution, is (almost) self evident: Enzymes do not perform feats of magic, they just accelerate reactions that tend to occur anyway. Biochemical reactions can therefore themselves harbor relics of, or be holdovers from, metabolic origin. Yet not all reactions are equally old, metabolism has evolved — but how? In this proposal, the tools of comparative physiology, thermodynamics, and comparative genomics, will be applied to investigate the process of early metabolic evolution. Three kinds of data stand central to the work: i) thermodynamic properties of reactions that comprise modern metabolic networks, ii) information contained in the ability of H2 in the presence of Ni3Fe and magnetite catalysts to substitute for ferredoxin and enzymes in biochemical reactions, and iii) information about the evolutionary origin and phylogenetic spread of heme and cytochromes as well as the ecophysiological context of cytochrome origin. The proposed work will deliver groundbreaking insights into the chemical environment at the site of biochemical origins, inform about the pre-enzymatic nature of catalysts and reductants at the origin of metabolism, and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Short Videos to Increase Learners uptake on Online Content' to be submitted under Horizon 2020.

assistant: **Abstract**

Introduction:  Students use the Internet as the first point of contact when searching for learning materials to assist their studies.  Such content may have a low evidence based background and may be misleading. One learning medium that is rated highly by students is the use of short educational videos. Objectives: The aim of this project is to create short video learning materials which are peer reviewed and accessible for dental students. Their creation and use will be an exemplar that may be used in dentistry and have a framework that allows translation into other disciplines. Material and Methods: A questionnaire will be distributed to European Dental Courses to verify their use of Information and Communication Technologies (ICT) with a focus on the use of short online videos. Following this short instructional videos will be created in several dental subjects and made available online following peer review. Their content will be evaluated qualitatively using face to face interviews with both students and their teachers. Following dissemination at dental education conferences, selected European partners will be invited to take part in evaluating the videos with a view to embedded them in their curriculum.  The ER will learn new skills in qualitative research methodology and will develop a network of European Schools to evaluate new video production. Outcomes: This work will create a suite of dental videos that will be available to students across Europe.  They will be peer reviewed and made available via the Internet to students. The project will develop a framework for future video creation by educators and will allow translation to other disciplines. The ER will learn a range of multidisciplinary skills including video creation, qualitative research methodology an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Pathways common to brain development and ageing: defining strategies for preventive therapy and diagnostics' (DEVELAGE), addressing dissemination and exploitation.

assistant: **Impact**

The increasing number of elderly people will have a major impact on the prevalence of age-related diseases, which will pose major challenges to keep health systems in Europe sustainable. Current knowledge is insufficient to identify the transition of normal brain ageing into Alzheimer`s Disease (AD)-like brain damage. Elucidation of the genes and pathways contributing to the earliest stages of AD pathology and associated neurodegeneration should be instrumental to allow intervention when the condition is still reversible. The aim of the DEVELAGE project is to characterise shared molecular pathways between early developmental processes in the brain and brain ageing. Our concept is based on the hypothesis that disorders of neural development contribute to age-related neurodegeneration, that developmentally essential proteins might have a role in neurodegeneration, and that neurodegeneration-related proteins and genes are important during the development of the brain. The DEVELAGE approach is unique in that it is brain tissue-based, derived from neuropathological diagnosis with detailed molecular analysis of the spectrum of developmental and ageing changes in the very same brain samples used for a comprehensive array of investigations in humans as well as in experimental models at genetic, epigenetic, transcription and protein levels. DEVELAGE contributes to the understanding of biological variation by examining relevant number of cases with different phases of ageing and neurodegeneration as well as developing brains with or without developmental disorders. Pathways examined in humans will be validated in animal models, including a non-human primate, and vice versa. The combination of human samples and animal models susceptible to experimental manipulation will promote th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Development of a Method for the Exploration the Joint Geology-Geophysics Model-Space' (GeoMos) targeting Horizon 2020.

assistant: **Abstract**

Subsurface modelling using geoscientific data is essential to understand the Earth and to sustainably manage natural resources. Geology and geophysics are two critical aspects of such modelling. Geological and geophysical models have different resolutions and are sensitive to different features. Considering only geological or geophysical aspects often leads to contradictions as creating an Earth model is a highly non-unique problem. In addition, the sensitivity of the data is limited and many objects cannot be differentiated by a single discipline. The only way to address this is solving the longstanding challenge of integrating of geological data and knowledge (orientation data, contacts and ontologies) and geophysical methods (physical fields). Recent techniques usually focus on features the data is sensitive to and merely use one discipline to falsify hypotheses from the other. Such approach prevents considering the full range of potential outcomes, and fails to exploit the sensitivity of both approaches. This project proposes a different philosophy to solve the challenge of connecting geological and geophysical modelling. It first involves the development of a novel method integrating the two model types in a single framework giving them equal importance. Geological and geophysical data will be modelled simultaneously through an implicit functional mapping one domain into the other by linking their respective models. This will allow the simultaneous recovery of compatible geological and geophysical models. Secondly, this project will use a new hybrid deterministic-stochastic optimisation technique to explore the range of subsurface scenarios to estimate the diversity of features that cannot be differentiated based on the available data. Thirdly, after proof-of-conce