RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'International Energy Agency support action for clean energy transitions in emerging economies', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

This H2020 funded Coordination and Support Action (“Action”) is intended to assist a select number of emerging economies to implement actions to fulfil global clean energy and climate targets, in line with the Paris agreement. Built on a foundation of fact-based insights and tangible recommendations, the Action’s objective is to guide policy makers on how to push ahead in sector reforms, attract investments, foster innovation and ultimately enable a clean energy transition in selected emerging economies.In addition to this focus on policy makers, the Action is also intended to support policy implementing stakeholders such as regulators, system operators, local authorities and developers. A broader audience will also benefit directly and indirectly from certain data and other deliverables produced and made publicly available under the Action. The Action is intended to focus on a number of specific regions and topics, with a particular focus on major emerging economies (such as China, Indonesia, Brazil and India). Throughout this proposal these countries are referred to as “priority countries”.The intended specific objectives of the Action are to:•create more effective knowledge and information sharing and create capacity to enable stronger policy action and alignment of investment flows, including via country-specific reviews of policies, supported by scenario modelling where relevant;•strengthen international energy and climate plans in a way that complements existing initiatives, support multilateral efforts to facilitate and enable National Determined Contribution (NDC) implementation, increase collaboration between experts across priority countries and share relevant global expertise; •encourage innovation for the promotion of clean energy technologies and related in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Automated Rail Cargo Consortium: Rail freight automation research activities to boost levels of quality, efficiency and cost effectiveness in all areas of rail freight operations' to be submitted under Horizon 2020.

assistant: **Abstract**

The overall aim of this specific Automated Rail Cargo Consortium (ARCC) proposal is to carry out an initial phase of rail freight automation research activities in order to boost levels of quality, efficiency and cost effectiveness in rail freight operations of the European railway sector. The three areas of research activities are: Transporting and delivering freight via automated trains, developing automated support processes at the nodes (e.g. terminals, yards and transhipment points) and advanced timetable planning.If automation and digitalisation processes are exploited in an appropriate way, rail freight transport can generate significant positive impacts for rail freight transport. For example, increased efficiency on the main railway lines and nodes, reducing lead time and energy costs. Additionally, improved services and customer quality so that the operational timetable is met reliably. Furthermore, optimised business processes and management of complex situations, such as a 15% reduction in time when rail assets sit idle within nodes.The Consortium is made up of Joint-Undertaking (JU) members of Shift2rail who are the main drivers in developing and transferring automation technologies and processes to the railway freight sector.The project will start with a Grade of Automation, level 2 (GoA2 level) demonstration and end with a GoA3/4 level crossborder demonstration. The start-up activities in this first batch of Shift2Rail projects will be followed up, in subsequent development phases to achieve higher levels of technical readiness, beyond the 36 month project period.


**Keywords:** Rail Freight Automation, Automated Driving, Process Automation, Real-time data
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Modelling nanoparticle transport in the extracellular matrix: improving drug delivery with ultrasounds', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Cancer is the second most important cause of death in Europe, with an estimated 2.27 million new cases and 1.3 million deaths in 2020. The prerequisite for a successful medicinal therapy is that the drug reaches its target and that toxicity towards healthy tissue is limited, however the systemic injection of drugs leads to less than 1 % of the drugs accumulating in solid tumours. Relying on the permeability of the blood vessel in cancer tumours, the encapsulation of drugs in nanoparticles (NPs) constitutes a promising approach for cancer treatment. However, the homogeneous distribution of NPs in the tumour tissue remains a challenge. To reach all cells in the tumour the NPs must cross the extracellular matrix (ECM), a major component of solid tumours consisting mainly of a network of collagen fibres embedded in a hydrophilic gel of proteoglycans. Together, they limit the diffusion of drugs across the tumour. Focused UltraSound (FUS) exposure has been reported to improve the delivery of NPs to tumour cells. FUS induces acoustic radiation force and cavitation that can lead to microstreaming or shock waves but the underlying mechanism(s) for the improved transport are not well understood. Successful delivery depends on many factors including the pathology, structure and composition of the diseased tissue, the characteristics of the NPs, and the exposure parameters of the FUS, making it a complex problem difficult to solve using an experimental approach. In this project, we will use molecular modelling to identify correlations between the molecular details of NPs and ECM, and FUS exposure parameters with NP transport across the ECM, creating a predictive model for FUS delivery of NPs and drugs to diseased tissue. The model, validated by experimental data, will contribute to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Energy-aware Aerial Swarm Search for Efficient Search and Rescue', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Flying robots show great potential in many diverse applications as they can rapidly travel over rough terrain, naturally overcome large obstacles and can provide powerful sensing with a bird's-eye view. Swarms of flying robots are robust due to redundancy, allow for parallel operation and can help each other, for example to cover vast outdoor areas or to create mobile sensor networks. Swarms of flying robots can be deployed for searching tasks in disaster situations, such as in earthquakes or terrorist attacks, to locate humans who may need help.Swarm intelligence techniques would also enable these flying robots to collaborate with each other in order to solve certain problems they may encounter, which may not have been possible with a single flying robot.One of the main limitations with flying robots is the limited amount of energy available for flying. This limitation is heavily dependant on the battery technology that is currently available, equating to approximately 15 to 30 minutes for platforms with a diameter of 100cm or less.We propose a new method to help mitigate this limitation by using swarms of flying robots that are energetically connected to a centralised energy station called a HiveShip. The batteries of each robot will be automatically hot-swapped when their energy is depleted, thus allowing for continuous operation during a searching task, similar to bees travelling back and forth from a hive. Such a platform would create the possibility for some interesting research in aerial swarm intelligence.The aim of this project is to design and build a prototype of a HiveShip, including several autonomous flying robots, and to develop some basic swarm intelligence behaviours with in-field experiments.In this project, we intend to:- develop the aforementioned Hi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Dendritic Cells in the Pathogenesis of Atherosclerosis'.

assistant: **Objectives**

Atherosclerosis is the main cause of death in the industrial world. The understanding of the pathogenesis has led to the notion of atherosclerosis as a chronic inflammatory disease. The evidence of a network of vascular-associated dendritic cells (DC) in arteries of healthy young individuals, as well as findings demonstrating an infiltration of atherosclerotic plaques where DC accumulation in close contact with macrophages/ monocytes and T-cells implies an important role of DC suggests a functional role of DC, in the activation of the vascular immune system and in the pathogenesis of atherosclerosis. So far the molecular mechanisms regulating the recruitment and causative role of DC in the formation of atherosclerotic plaques remains to be elucidated. DC derives from hematopoietic cells but also peripheral monocytes. So far, several different markers have been used to detect DC in atherosclerotic lesions, however, these are of low specificity.The CCL17 chemokine (also referred to as dendrokine) is expressed only by mature DC. Using an eGFP knock-in, CCL17 knock-out, crossed into the atherosclerosis prone apolipoprotein E deficient (apoE-/-) background, will allow us to specifically study the role of DC in pathological pathways operative in atherosclerosis. The infiltration and localization of DC in atherosclerotic lesions will be studied by detection of GFP-expressing DC in heterozygous CCL17E/+ apoE-/- mice by dual photon microscopy. Double knockout mice will be used to evaluate the role of DC and of their effector chemokines CCL17 in lesion development in native atherosclerosis. Furthermore, in vitro and in vivo assays will be performed to investigate the instruction or modulation of a specific immune response during the initiation and progression of atherosclerotic l
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Open Platform for X-Ray robotics medical imaging and surgical navigation' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

SURGIS aims at creating a completely new computer-assisted, integrated system to support Minimally Invasive Surgery (MIS). It is based on a robotics X-ray 2D/3D imaging system. SURGIS is innovative and disruptive in two ways: a) the envisaged product itself: a novel solution that integrates formerly isolated systems providing enhanced and new functionalities, higher accuracy and significantly improved usability. Experienced users are developing it for users. And b) with regard to its technological approach and the corresponding business model: an open source environment, which will provide the ground to nurture the commercial exploitation and further development of applications by 3rd parties. It represents a platform and an ecosystem where developers and users are encouraged and facilitated to boost both the economic and clinical effect of SURGIS itself.Once implemented SURGIS will deliver the following value propositions:1.Robotic 5-axis C-Arm usable in 2D and 3D mode2.Integrated Surgical navigation system with automatic continuous calibration3.Calibrated MIS surgical tools4)Open software platform for the development of third-part applicationsA laboratory technology demonstration platform has been built and a preliminary study of existing IP has not discovered significant hurdles: we have strong reasons to believe that the final outcome will be successful despite the challenging goal.The feasibility study of Surgis will be performed along 5 main points:1.Interviews with 10-20 international leading surgeons(Europe/USA) to assess clinical/technical potential of project and get suggestions for improvement;2. Assessment of the technical and contractual framework for implementing the open platform and allowing the integration of third-party application.3.Study to evaluate
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Palladium - ii - catalyzed addition polymerization of fluorinated norbornene derivatives' in the context of a Fourth Framework call.

assistant: **Objectives**

Research objectives and content The metal-catalyzed polymerization of olefins is of outstanding industrial importance. Besides classical polymers such as polyethylene and polypropylene, polyolefins that contain cyclic subunits have gained more and more interest. This is because these polymers possess interesting properties, e.g. the glass transition temperature is increased by the rigid norbornane units. Since fluorinated polymers possess also a number of advantageous properties, polymers which contain fluorinated cyclic subunits are potential materials for high-tech applications, e.g. in light-conducting fibers. The current project aims the vinyl polymerization (Ziegler-Natta) of fluorinated norbornene derivatives by means of a new class of (n3-allyl)palladium(II) catalysts. In contrast to many other transition metals, the palladium does not give rise to any ring opening metathesis polymerization (ROMP), which competes with the vinyl polymerization. The monomers are easily accessible by Diels-Alder addition of cyclopentadiene to fluorinated alkenes. Training content (objective, benefit and expected impact) The research I was involved in recent years was focused on basic reseach in the area of polymer synthesis. A co-operation in Dr. Risses group would give me the opportunity of improving my knowledge in an area of much more industrial importance. Links with industry / industrial relevance (22) The project is currently supported by BASF, which is interested in Pd-catalyzed cyclic olefin polymerizations.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Development of advanced surface engineering techniques for future aerospace transmissions' under Fourth Framework.

assistant: **Concept**

No summary available CONSENSUS REPORT PRIVATE 1. Clear, verifiable and realistic objectives within the scope and objectives of the programme Objectives clearly defined. Project aims at improving fatigue properties through advanced surface engineering. 2. Progress beyond the state of the art and innovative character Complete description of state of the art. Innovation lies in the combination of materials and technologies. Key mechanical and microstrucutal factors affecting fatigue are addressed. 3. Scientific and technological quality of the proposal Large experimental programme. Detailed description of work content and detailed deliverables. 4. Quality of management and competence of the partnershipMutidisciplinary approach involving partners having high scientific and technological level. Adequate management plan and well structured proposal. 5. European dimension and related benefits Interactive work will strenghten ties between European helicopter manufacturers and their suppliers. 6. Economic, industrial, safety, social & environmental impacts Economical benefits and safety impacts by increase of fatigue resistance. 7. Exploitation policy - consistency with corporate strategy of the industrial participants Adequate exploitation is ensured by the composition of the consortium. 8. Other remarks: e.g. Cost estimation 77.7-7- Z:phoenixx,,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Architecture and Applications of Green Information Centric Networking' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Information Centric Networking (ICN) is a new paradigm where the network provides users with named content, instead of communication channels between hosts. Research on ICN is at an early stage, with many key issues still open, including naming, routing, resource control, security, privacy and a migration path from the current Internet. Also missing for efficient information dissemination is seamless support of content-based publish/subscribe. Further, and importantly, current proposals do not sufficiently address energy efficiency. GreenICN aims to bridge this gap, addressing how the ICN network and devices can operate in a highly scalable and energy-efficient way. The project will exploit the designed infrastructure to support two exemplary application scenarios: 1) The aftermath of a disaster e.g., hurricane or tsunami, when energy and communication resources are at a premium and it is critical to efficiently distribute disaster notification and critical rescue information. Key to this is the ability to exploit fragmented networks with only intermittent connectivity; 2) Scalable, efficient pub/sub video delivery, a key requirement in both normal and disaster situations. GreenICN will also expose a functionality-rich API to spur the creation of new applications and services expected to drive EU and Japanese industry and consumers into ICN adoption.Our team comprising researchers with diverse expertise, system and network equipment manufacturers, device vendors, a startup, and mobile telecommunications operators, is very well positioned to design, prototype and deploy GreenICN technology, and validate usability and performance of real-world GreenICN applications, contributing to create a new, low-energy, Information-Centric Internet. Our expertise and experience in sta
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Mechanism, Regulation and Functions of DNA Loop Extrusion by SMC complexes'.

assistant: **Objectives**

Life and evolution of organisms relies on the maintenance, integration, propagation, and readout of genetic information. This information is stored in chromosomes that have a specific three-dimensional structure, a condensed yet accessible form of DNA that is dynamically folded during the lifespan of cells. How DNA is folded within chromosomes has however remained a mystery. It has been proposed that this is achieved by a process of loop extrusion in which SMC (Structural Maintenance of Chromosomes) complexes that are multi-subunit ATPases present in all kingdoms of life – including condensin and cohesin – reel DNA into loops, thereby organizing genomic DNA into higher-order structures. Recent in vitro single-molecule studies, stimulated by our initial discovery on condensin, provided direct evidences that both condensin and cohesin can indeed generate chromatin loops by extrusion. However, the most fundamental questions relating to this process remain unanswered: What is the molecular mechanism of loop extrusion? How is this process regulated? What are the functional roles of SMC-mediated loop extrusion beyond condensation? To address these questions, we will synergistically combine our single-molecule loop extrusion assay with correlative light and electron tomography and force spectroscopy to reveal both dynamic and structural aspects of loop extrusion and SMC proteins. Specifically, we will resolve how SMC complexes function as molecular ‘motors’, how regulatory factors modulate the kinetics of loop extrusion, and how loop extrusion impacts cellular functions like chromosome segregation and gene recombination, all at the single molecule level. In the long term, our findings will provide vital insights into the basic packaging structure of the genome which directly g