RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Sequence based strategies to identify genetic variation associated with mental retardation and schizophrenia' (GENOVAR).

assistant: **Innovation**

Mental retardation (MR) and schizophrenia (SCZ) are disorders of the brain that affect 2-3% and 1% of the population, respectively. Both disorders are considered to be highly heritable, but exhibit heterogeneous genetic etiology. Recent genetic studies have led to discoveries that the same variants that can give rise to different neuropsychiatric disorders, including MR and SCZ. In this proposal, sequencing will be used to identify novel genes involved in MR and SCZ, and to explore the potential overlap between these disorders. The specific goals of the research plan include:1. Genetic characterization of patients from large pedigrees with SCZ and MR.Five pedigrees have been collected in which multiple individuals are affected by SCZ or MR. The pedigrees vary in size, with the largest spanning 12 generations including 3,400 individuals. Exome and whole genome sequencing will be performed to identify the genetic variants associated with disease. Candidate genes identified will be screened in large independent cohorts of MR and SCZ patients. In addition, RNA sequencing will be performed on cell lines established for patients and controls from two of the pedigrees.2. Screening of trios to identify novel genes causing MRMental retardation (MR) patients are typically referred for array-based analysis. With current genetic screening using microarray, a clinically significant rearrangement is identified in 15-20% of patients. I propose use high throughput sequencing to screen MR patients and their parents with the goal of identifying new MR genes and to investigate to what extent the diagnostic yield can be increased.By combining sequencing, bioinformatics and carefully selected clinical material, the work presented in this proposal will lead to an increased understanding of d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Integrated Aftertreatment System of DI Diesels for Cars' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Objectives and content Passenger cars with direct injecting diesel engines offer the greatest potential at present of complying with the stricter emission limits which will be incorporated in future legislation. Such engines have an extraordinarily low fuel consumption, but present problems in future in respect of the limits proposed in the EU Exhaust Regulation Stage III for all diesel engines with effect from October 1999. The manufacturers of such engines urgently need reliable exhaust aftertreatment methods to enable the limits for oxides of nitrogen (HC + NOx 0.5 g/km) and the particulates (0.04 g/km) to be assured. The integrated systems which it is intended to develop in this project, consist of: - a selectively acting NOx catalyst in oxygen-rich exhaust - a reductant dosage system including a sensor-aided control strategy for dynamic vehicle operation - a catalytically coated soot filter - a control strategy which matches exhaust temperature to the requirements of exhaust aftertreatment through engine and heat management. Taking four different vehicles with DI diesel engines of different manufacturers, the aim is to demonstrate the extent to which the idea of an environmentally friendly vehicle can be accomplished. Engine performance and fuel consumption should not be adversely affected as a result. The consortium consists of three reputed vehicle engine manufacturers (VW, MB, Fiat) who are the principal users of the developed systems, an industrial catalyst manufacturer (JM) and an exhaust system manufacturer (ZS), both of whom will make use of the results for enlarging their range of products for environmental protection. Specialized institutes of advance technology are active throughout Europe in the field of NOx catalyst (K. U. Leuven), in soot filter regene
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Algorithms for Analysis of Genes and Genomes' to be submitted under Seventh Framework.

assistant: **Abstract**

In this project, we propose to develop new algorithms and probabilistic models for analysis of biological sequences (genomes and proteins encoded by them). We concentrate mainly on computer science aspects, striving to design efficient algorithms capable of processing large biological data sets currently available. In collaboration with molecular biologists, we will apply our techniques to several bioinformatics problems, such as finding location of genes in genomic sequences, evolution of duplicated regions of the genome, and study of mitochondrial genomes of yeast. Finding better solutions for these problems will lead to better genome annotations available as a basic resource for biological and medical researchers. In addition to the research objectives, we plan to establish lasting collaboration between the computer science researchers at the Faculty of Mathematics, Physics and Informatics and the life science researchers from the Faculty of Natural Science at Comenius University, Bratislava. We will involve faculty members and students from both faculties in common research projects, seminars and other activities. Dr. Tomas Vinar has experience with interdisciplinary bioinformatics research at leading universities in Canada and U.S.A. which makes him an ideal candidate for this effort.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Accelerating market introduction of the first real-time diagnistic and monitoring device for upper gastrointestinal bleeding (UGIB)'.

assistant: **Concept**

Upper gastrointestinal bleeding (UGIB) is a potentially life-threatening condition that affects approx. 2 million people annually in Europe and in the United States. Current UGIB diagnosis comprises a long and slow set of laboratory tests and culminates ultimately with an endoscopy which is the only conclusive mean for UGIB diagnosis. This results in an over usage of endoscopic resources every time there is a suspicion of a bleed. Clinical data shows that up to 60% of the time endoscopy and consequent hospital admission is not necessary. In addition, endoscopy is invasive, expensive (approx. €2433) and cannot deliver prolonged monitoring. Multi-disciplinary consortium led by EnteraSense are developing a disruptive technology ‘PillSense’ which enables real-time detection of UGIB and subsequent monitoring of high risk patients without the need of endoscopy. The product includes an ingestible capsule and an external receiver. The capsule contains an optical based sensor to detect bleeding in the upper gastrointestinal tract. EnteraSense development team has already proven the core technology through lab-testing and in-vivo clinical studies. During this FTI project, the consortium aims to optimise PillSense product design, gain regulatory approvals, develop a commercial scale manufacturing process and gain clinical approval through two stages in-human clinical trials. Successful development and commercialisation will enable consortium to generate revenues of €59million and a gross profit of €29million over five years- post commercialisation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Active Suspensions with Controlled Interaction Rules' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Self-propelling, i.e., active colloidal particles constitute a novel class of non-equilibrium systems which exhibit structural and dynamical features similar to those in assemblies of bacteria or other motile organisms. Due to their reduced complexity, they provide an intriguing chance to understand the formation of dynamical structures in non-equilibrium systems in unprecedented detail. A central question in this rapidly growing field is, how interaction-rules determine the creation of e.g. swarms or complex networks. In addition to ordinary inter particle and hydrodynamic forces, interaction-rules can be much more complex. For example, they can regulate the particle motility depending on their relative orientation, their local density or otherwise distinct particle configurations.Here, we propose an experimental approach which aims towards controlling the amplitude and direction of the particle’s motility in dense active suspensions on a single particle level. Particle-propulsion is achieved by a light-activated diffusiophoretic mechanism, where the particle motility is controlled by an incident light field. By means of an acoustic-optical modulator and a feed-back loop, we create dynamical and spatially-resolved light fields which depend on the current configuration of active particles and user-defined interaction rules. Because these rules are imposed externally and not by internal forces, this permits the experimental realization of a wide range of rules (linear, non-linear, and even non-reciprocal) in dense, two-dimensional active systems. We expect, that the experimental realization of user-defined interaction-rules largely extends our understanding how active matter can organize in dynamical structures. In addition, the perspective of enhanced control of active
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Noble Metal Loaded Oxygen-deficient Mesoporous Tungsten Trioxide for Green Catalysis under Solar Light', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

With the increasingly serious energy and environmental problems caused by the combustion of fossil fuels, the development of efficient solar light driven photocatalysts for green chemical synthesis is an urgent task at present. In this project, the synthesis and solar light driven green catalytic applications of noble metal (Au, Pd, or Au-Pd) loaded oxygen deficient mesoporous tungsten trioxide are proposed. The objectives of this research proposal are to use the as-prepared photocatalysts for the high selective synthesis of hydrogen peroxide from water and molecular oxygen without the usage of hydrogen gas, and to use the in-situ formed hydrogen peroxide for directly oxidation of alcohols and primary carbon-hydrogen bonds in toluene with high selectivity under solar light. A series of mesoporous tungsten trioxide can be facilely prepared by a hard template replicating method using mesoporous silica as template and phosphotungstic acid as a precursor. Oxygen deficient mesoporous tungsten trioxide will be prepared by hydrogenation treatment under different temperature. The interconnected mesopores in tungsten trioxide are beneficial for the adsorption of noble metal precursors. Noble metal nanocrystals would be formed by in-situ reduction on the oxygen deficient mesoporous tungsten trioxide under solar light irradiation. The special heterojunction of noble metal nanoparticles and oxygen deficient mesoporous tungsten trioxide semiconductor will result in high-performance, stable novel photocatalysts for green catalysis under solar light. The new catalytic concepts by the utilization of solar light for highly efficient green chemical synthesis proposed in this project will provide great benefits for both the whole chemical industry and our environment.


**Keywords:** Phot
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Rational use of energy in electrochemical processes to recover metals and to regenerate metal ions containing aqueous liquids from industrial plants using hydrogen' in the context of a Fourth Framework call.

assistant: **Objectives**

Objectives The recovery of metals and the regeneration of electrolytes become increasingly important. Thus the objective of this project focuses on the implementation of an industrial scale energy saving clean process for the recovery of metals by a reduction of ions using hydrogen. The process should allow the re-use of the deposited metals as well as the recycling of the purified liquids. This demands a long term stable gas diffusion electrode and a close process performance. Technical approach Due to their large specific surface area, three-dimensional electrodes, in particular packed bed electrodes, are very useful for the reduction of metal ions at very low concentrations. To reduce metal ions in a dilute solution, it is planned to use an electrochemical reactor consisting of a hydrogen gas diffusion electrode (GDE) in direct contact with a packed bed electrode where two electrochemical processes occur simultaneously and spontaneously. This electrochemical cell consists of two different electrodes (a gas diffusionand a bed electrode give the name to the cell) is called a GB-cell (GBC). No external power supply is necessary to reduce ions (e.g. Cu2+, CrO4-, Fe3+) with hydrogen. Any reduction process which is thermodynamically possible can be carried out in this reactor. Present gas diffusion electrodes, which have been developed for application in fuel cells are loaded with high active catalysts, which are very sensitive to organic and inorganic pollutants. A less active catalyst would be preferable since the required rate of hydrogen oxidation is relatively low and these catalysts are less sensitive to poisoning. A pilot plan will be designed, constructed and operated under industrial conditions. Expected achievements and exploitation At present, there is no experi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Development of mathematical models of novel hpv-based cervical cancer screening protocols for evaluation of the projected health and cost benefits' to be submitted under Fifth Framework.

assistant: **Abstract**

The objective of the project is to develop mathematical models of HPV/cytology based cervical cancer screening protocols for the evaluation of the health and cost benefits for EU states. The long-term performance of a combined HPV/cytology regimen on a country-specific basis is established from screening trials that rerunning in 6 different European countries and combined at a European level. In addition the costs of existing cervical cancer screening programs and related healthcare actions are collected. These data will be combined in mathematical models used to evaluate clinical outcomes and healthcare cost benefits for different scenarios. The outcome of this analysis will be used to develop interim, fully coasted, country- and EU-specific cervical cancer screening protocols, whichwill be used to start an informed debate leading to the development of a new European consensus policy for screening of cervical cancer.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Clean Air - Reduce Vehicle Emissions' (CARVE).

assistant: **Innovation**

Challange: Air pollution is a huge problem causing millions of deaths each year and one of the main contributors is NOx emission from diesel vehicles. To counter this the EU Euro Standards were introduced in 1990, designed to limit the harmful emissions. Increasingly strict legislation has been imposed, but existing technologies have not yet been able to meet the set NOx emission limits under real-world driving conditions, and as a consequence there has been no significant impact on NOx emissions.Solution: Amminex’ ASDS technology offers a beyond state-of-the-art solution for reducing NOx emissions under real-world driving conditions, thus enabling diesel vehicles to meet Euro Standards and future tightened standards, while at the same time securing a significant reduction in the fuel consumption. Even though competing solutions are able to meet current Euro Standards in lab tests, they are not able to reduce NOx emissions from exhaust efficiently under real-world driving conditions, which is why the air pollution problem remains unsolved. The unique ASDS solution has the ability to meet Euro Standards in both lab-testing and in real-world driving tests, and consequently make a real contribution to improving air pollution. The project: Amminex has already developed a retrofit system with the ASDS technology, which has been demonstrated on city busses with excellent results. Based on this retrofit product, the objective for this project is to develop and optimise the technology from a retrofit to a first-fit solution for the two segments: passenger cars and light commercial vehicles (vans).The customers: The two most relevant market segments for the further development of the ASDS technology are diesel passenger cars and diesel vans worldwide, for which this project sets
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Cooperative Optimal Control of Solar Plants'.

assistant: **Objectives**

The main objective is to demonstrate that the Multiple Scenario Cooperative Model Predictive Control (MSC-MPC) algorithms developed under the Advanced Grant OCONTSOLAR can be effectively applied to optimize the production of commercial solar plants.This proposed PoC aims to validate the MSC-MPC algorithms developed in OCONTSOLAR not only for the solar field for the entire solar power plant. The proposal addresses optimal scheduling and control while accounting for the intermittent and stochastic nature of solar radiation and electricity market prices. Specifically, Model Predictive Control based on multiple scenarios will be used to manage uncertainties.The experiments and demonstrations will be conducted on a commercial plant. If successful, the involved company intends to apply these results to other plants. Furthermore, the proponent believes these techniques could be extended to other types of power plants.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Empowerment of Mental Illness Service Users: Life Long Learning, Integration and Action' to be submitted under Sixth Framework.

assistant: **Abstract**

EMILIA is an integrated project which addresses the requirements of the workprogramme 2.1.4 with respect to LifeLong Learning. It makes a substantial contribution to the European Research Area by providing new momentum through: better use of instruments of indirect support, the development of information networks, and the encouragement of the exchange and spread of good practice and information exchange. It addresses the ethical issues involved in research of this scale thoroughly. It also seeks to develop a common system of scientific and technical reference for policy implementation particularly in the areas of LifeLong Learning, Social Inclusion, and employment. Research activities will comprehensively review LifeLong Learning strategies and explore these as a means for achieving empowerment and social inclusion for selected groups of citizens with an emphasis on disability groups, including mental health service users. Central to the research are two linked research designs: a multi-site organisational case study and a multiple site time series design. Subsequent activities focus on the effectiveness of lifelong learning approaches for mental health service users. The EMILIA project will in addition demonstrate a high level of innovation through achieving the empowerment of mental health users and reducing their social exclusion through the innovative use of LifeLong Learning. This project seeks to empower mental health service users and encourages mental health service users to maximise service user involvement in the training for and delivery of new and innovative services, and by so doing, opening up new employment routes for service users, thus integrating European Union employment strategy within it. Accredited training is offered to develop service user capabi