RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Re-thinking the Green Revolution in the Medieval Western Mediterranean (6th - 16th centuries)' (MEDGREENREV) under Horizon Europe.

assistant: **Objectives**

As Mediterranean societies prepare for the impacts of climate change over the next few decades, a case study to inform their future resilience is associated with one of the defining events in world history: the emergence of Islam in the 7th century, the subsequent Arab (and later Berber) conquests of the southern and western Mediterranean, their associated population movements and the environmental adaptations that enabled these new societies to flourish. The introduction of new forms of agriculture that transformed the economies of the conquered regions has been previously framed as the “Green Revolution”. Moving beyond the limited focus of earlier research, with its restricted spatial and chronological scope, this project will adopt an integrated ecological approach, encompassing plants, animals and soils, from production through to consumption, and compare the impact and legacy of environmental transformations associated with long-term societal change in the western Mediterranean (Iberia and Morocco), beyond the initial Arab/Berber conquests. Adopting a broader chronological span, from the century before the conquests through to the century after the dissolution of the last Islamic polity in Iberia, the transition from Islamic to Christian regimes in Iberia will be compared, for the first time, with the persistence of Islamic polities in northwest Africa, against the backdrop of climatic fluctuations. This will enable relationships between environmental transformations and sequences of political and demographic change to be effectively contextualised. The synergy between our groups will combine regional specialisms with a wealth of scientific expertise, enabling us to conduct the first long-term and inter-regional study of how conquest, migration and encounters with
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'TRAMPOLINe-: A training programme to promote the industrial adoption of microbial electrochemical technologies'.

assistant: **Concept**

A training programme to promote the industrial adoption of microbial electrochemical technologies.TRAMPOLINe- is a joint academic-industrial inter-disciplinary initiative which has the primary goal of training a pool of young researchers in the field of microbial electrochemical technologies (METs) while developing innovative and ready-to-be-applied solutions for tacklingglobal environmental challenges, including contamination of the remaining freshwater sources, unsustainable production processes,anthropogenic CO2 emissions and the transition towards renewable energy environment.The main aim of TRAMPOLINe- is to form a collaborative network that (i) connects leading researchers in the core MET disciplines with SME/large companies, (ii) upgrades the state-of-the-art (SOTA) of METs into prompt industrial adoption, and (iii) trains a set of young researchers to become highly skilled MET scientists Due to the multidisciplinary nature of METs, the upgrading of MET-based cutting-edge technologies calls for international inter-sectoral cooperation in view of its proper industrial adoption. The doctoral training is carried out in research groups that are developing progressive technologies and materials for applying METs with active involvement of industrial partners that can support the market adoption of the technologies. The candidates will be developing MET-based technologies focusing especially on bioremediation, desalination, industrial bioproduction, resource recovery and on the production of CO2-based chemicals. Comprehensive technology development is supported by the work packages dedicated to microbiology of electroactive microorganisms, engineering redox reactions and reactors, innovative materials, MET-based industrial bioproduction, environmental applications and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Hybrid Nanophotonics for Enhanced Light Control' (HYNANO).

assistant: **Innovation**

Coupling of quantum emitters, and the exploitation of multi-photon quantum interference, is the next challenge for generation optical information technology and quantum computation. The aim of this proposal is to achieve long-range coupling of two or more quantum emitters, understanding the fundamental mechanisms of light transport, nano-optical emission control and resulting collective phenomena, such as super-radiance and lasing.A model system will be realised where the light originated from one quantum emitter is transported to the next one by a combination of photonic crystal waveguide and optical nano-antennas which together act as a bridge for light transport from the micrometer to nanometer scale.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Virus-like particles: the next step in gene therapy'.

assistant: **Concept**

Virus–like protein particles can be applied as carriers for RNA gene therapy. The release of the RNA, however, is still a major problem. The goal of this proposal is to develop new routes towards the controlled opening of the virus capsid combining the cutting-edge science of bioconjugate chemistry and virology. This project intends to find a suitable carrier among non-infectious virus particles for small interfering RNA (siRNA) to be used for gene therapy. siRNA has the ability to specifically degrade RNA of a particular sequence and selectively stop the production of an abnormal undesired protein, which makes it a very promising therapeutic agent. The major obstacle, however, is to find an efficient method for cellular delivery of the RNA material. Virus-like particles, that are self-assembled protein cages, have the potential to be used as addressable carriers for siRNA. The Finn Group at the Scripps Research Institute has recently developed a method to produce virus-like particles that contain siRNA. The goal of the project is to engineer this particle, such that it successfully delivers the RNA into the targeted cell. This project will have the potential to make significant contributions to the fields of biomedicine and targeted drug delivery, strategically important areas identified by the European Technology Platform on Nanomedicine.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Environmental design of low crested coastal defence structures (DELOS)' (DELOS).

assistant: **Concept**

The aim of DELOS is to identify engineering options in the design of coastal defence structures that are functionally and economically feasible and socially and ecologically acceptable. DELOS offers the possibility to achieve this aim through integrated collaboration among engineers who design coastal defence systems, coastal oceanographers, marine ecologists, economists and political institutions who are operationally responsible for coastal protection works. DELOS covers major research in engineering, ecology and socio-economy. It involves 17 partners from 7 European countries. The major anticipated deliverable are validated guidelines for the design of low crested coastal defence structures to be provided to civil engineers and local authorities planning shore defence measuresProject results are summarised in the following. Ecology Ecological effects of LCSs are site-specific reflecting the complexity and variability of natural systems. LCSs always produce an increase in biodiversity and generate inshore sedimentation that negatively affects the landward soft bottom habitat. LCSs design criteria must be addressed to:- promote the development of salubrious areas in the protected zone by increasing the water flow through the structures;- reduce to the minimum LCSs length to avoid large-scale effects of habitat loss, fragmentation and community changes;- increase structure stability, minimise maintenance works and manage human usage, to facilitate settlement/persistence of algae and marine invertebrates and reduce ephemeral green algae;- avoid situation and scouring that are felt as disturbances for abundance and composition of epibiotic assemblages, for instance by increasing berm width;- increase armour geometry complexity and heterogeneity that promote settlement of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Role of the calcium sensing receptor (CaR) in prevention of colonic hyperproliferation' in the context of a Sixth Framework call.

assistant: **Objectives**

Since sporadic colorectal cancer (CRC) is, to a major part, preventable, attempts at primary prevention are rational, timely, important, and should be a major priority. Calcium was identified as a chemopreventive agent, since higher intake is associated with reduced risk of CRC. Mechanisms by which high calcium intake prevents neoplastic transformation in the colon are still poorly understood. We willevaluate the role of the calcium sensing receptor (CaR) in colon in calcium-dependent regulation of proliferation. CaR transduces variations in extracellular calcium concentration into modulation of signal transduction pathways involved in proliferation and differentiation, and its expression is lost during colon tumourigenesis. We will use the Nuf mouse model, which has an activating mutation of the CaR, and thus constitutes a unique model to study its role. We expect that the colon of Nuf mice will have increased sensitivity to calcium and will show lower expression levels of proliferation markers when receiving low calcium diet, compared with wild type littermates. In parallel we will investigate signal transduction pathways regulated by CaR in colonocytes. Results of this project would represent an important achievement in colon cancer chemoprevention, a disea se that causes a considerable socio-economic burden. Indeed, if the CaR has a central role in mediating the antimitotic effect of calcium, its expression in precancerous lesions or early colon carcinomas might have predictive value for identifying patients responsive to chemoprevention by calcium. The training program of the fellowship will provide the applicant with further qualifications for the development of an independent research career, will give her experience to lead a research group and will provi de con
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Key coastal processes in the mesotrophic Skagerrak and the oligotrophic Northern Aegean : a comparative study' (KEYCOP) targeting Fourth Framework.

assistant: **Abstract**

MPA-Methodology: The MPA-Methodology developed in the course of the project comprises a continuous set of procedures, methods and tools for - the design of production modules according to the particular industrys objectives, modular production architectures and the derivation of scalable production systems,- the evaluation of alternative modular system solutions considering standardisation, flexibility and adaptability along the production system life-cycle, - strategies for migration from plant architectures of today to modular plant architectures of tomorrow. The MPA-Methodology adapts the concept of modular product platforms known from automobile design to the design of production systems. In order to increase production system flexibility and to extend its lifecycle, the system is decomposed into modules and platforms. While modules encapsulate the system constituents that are object to frequent changes within the systems lifecycle (i.e. product/ volume-specific constituents), platforms include the rather static parts of the system (i.e. location-specific constituents). This way, future changes of relevant parameters can be answered by exchanging or adapting dedicated modules.The methodology systematically supports the modular production engineering in four phases: analysis, design, evaluation and operation. At first, relevant change drivers for production systems and company-specific objectives are analysed. Based on that, production modules, platforms and reference architectures are generated. Therefore, change driver impacts and relevant system relations are represented in a dedicated model, the Production Structure Matrix (PSM). Systematic generation of alternative modularisation concepts is supported and the methodology provides a solution for the evaluation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'A multi-method perspective on children's use of rehearsal in serial recall tasks' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Rehearsal is a key construct in models of immediate memory and refers to the overt or covert repetition of items to counteract forgetting. A long-standing assumption is that children younger than 7 years do not engage in rehearsal, as such children tend not to show key ‘experimental effects’ thought to be signatures of rehearsal. However, given a growing debate in the adult experimental literature on the interpretation of these effects, and more recent concerns in the developmental literature about how one should understand changes in their magnitude, the questions of when rehearsal develops, and the role that it plays in supporting serial recall in children become open once again.These are theoretically and educationally important questions that cannot be addressed with the methods currently being used, and so the proposed project adopts a novel combination of three particularly informative approaches to properly address these issues. These methods from different traditions of memory research are: self-paced presentation times to index the pauses that participants insert into a task to allow rehearsal, rehearse aloud protocols that capture the participants’ rehearsal behaviour by making this overt, and trial-by-trial self-reports of strategy use. In total, 210 children between the age of 6 and 10 years will participate in three inter-linked experiments using these methods, with the relevant covariates of short-term memory capacity, working memory capacity, and articulation speed also being measured. A major strength of the proposal is that state-of-the-art multi-level modelling of the data will allow for modelling of both participant and task effects on trial level strategy use, avoiding the problems inherent in traditional analyses.This multi-method design coupled wit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Semantic web services interoperability for geospatial decision making'.

assistant: **Objectives**

Today, a number of non-semantic web services are available within the geospatial domain. The scarcity of semantic annotation and the lack of a supportive environment for discovery and retrieval make it difficult to employ such services to solve a specific task in geospatial decision making. SWING aims at deploying Semantic Web Service (SWS) technology in the geospatial domain. In particular, we address two major obstacles that must be overcome for SWS technology to be generally adopted, i.e. to reduce the complexity of creating semantic descriptions and to increase the number of semantically described services.Today, a comprehensive knowledge of logics, ontologies, metadata and various specification languages is required to describe a service semantically. We will develop methods and tools that can hide the complexity - and automate the creation - of the necessary semantic descriptions. The objective of SWING is to provide an open, easy-to-use SWS framework of suitable ontologies and inference tools for annotation, discovery, composition, and invocation of geospatial web services. SWING builds on the DIP and SEKT IPs, by adopting, combining and reinforcing their results. A main key to the solution is adapting the SWS technology of DIP to handle geospatial services and content. Another key is utilising and advancing the technology of SEKT to annotate geospatial services with semantic information.A targeted synergy between these two research initiatives are demanded to maintain and extend Europe's leading role in SWS. The SWING framework and pilot application will increase the use of distributed and heterogeneous services in geospatial decision making. The results can be reused in other domains and will boost the availability of semantic services and bring the vision of t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'DECiphering the role of long non COding Rna in cancer' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Increasing evidence indicates that non coding RNAs play a major role in the regulation of gene expression. A significant fraction of the non-coding transcriptome is represented by large intervening non coding RNA (lincRNAs), which seem to be involved with the epigenetic control of gene expression through binding with several members of the Polycomb Repressive Complexes (PRCs). Recently, dysregulation of lincRNAs has been associated to cancer. The HOTAIR lincRNA triggers the invasive program of breast epithelial cells by promoting epigenetic remodelling (Gupta et al., 2010). Although this report suggests an impact of lincRNAs in the transition to the metastatic phenotype, the role of lincRNAs in transformation remains largely unexplored. In this project I want to define the role of lincRNAs in the pathogenesis of cancer, using acute promyelocytic leukaemia (APL) as a model system. APL accounts for more than 10% of all Acute Myeloid Leukemias and is characterized by reciprocal translocations involving the retinoic acid α-receptor (RARα). APL blasts respond to all-trans retinoic acid (ATRA) treatment with differentiation, which involves epigenetic remodelling. The availability of new sequencing technologies coupled to tiling arrays and to the power of new computational biology programs, makes it now possible to study the whole non–coding RNA transcriptome. Determining the pattern of expression of lincRNAs during ATRA-induced APL differentiation, defining their functional significance, and deciphering the network of interactions between lincRNAs, the PML-RARα chimeric protein and the PRCs, will contribute to a better understanding of the nature of epigenetic deregulation in cancer and ultimately represent the basis to develop new anti-cancer strategies.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Training-Aided Broadband Wireless Networks' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

The underlying challenges in mobile and wireless systems are the unavoidable interference in wireless environments, and the time variance of the system. In general, high data rates give rise to frequency selective propagation whereas mobility induced Doppler shifts introduce time selectivity in wireless links. In order to develop efficient systems in these environments, an engineering solution is to use training signals. We analyse the use of training and develop design methodologies for these systems. As time and frequency selectivity increase, the optimal use of the training becomes more crucial.In particular, we study the combined effect of several factors at play in multi-carrier systems, in order develop a global framework of analysis. We study how these factors compare to a single carrier system operating over the same channel, in order to explore the gains of using multi-carrier transmission in a training-aided system. We also investigate the role of training in time-division duplex (TDD) systems. When beam forming in the forward link is used, the training in reverse and forward links have a unique interaction in such systems. We develop novel analyses and design techniques for training-aided TDD systems based on this interaction.