RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Cc chemokines in atopic and non-atopic - intrinsic - asthma' in the context of a Fourth Framework call.

assistant: **Objectives**

Research objectives and content It is widely accepted that eosinophils are critical effector cells in bronchial mucosal damage in asthma. I wish to identify cells in bronchial biopsies from asthmatics and controls, which transcribe and translate mRNA for the CC chemokines", eotaxin, RANTES MCP-3 and MCP-4. These newly discovered peptides are potent eosinophil chemoattractants. Professor Kay's group have developed novel technology which allows identification of the phenotype of chemokine- and cytokine-producing cells. I will study both allergic (extrinsic) and non-allergic (intrinsic) asthma and, as controls, use material from atopic non- asthma (mostly allergic rhinitis) and non-atopic normal subjects. Preliminary data shows mRNA-positive cells for eotaxin, RANTES and MCP-3 in bronchial biopsies from allergic asthma. The specific hypotheses are as follows: (I) There is increased gene expression of CC chemokines in both atopic asthma and non-atopic asthma (when compared to atopic non-asthmatics and non-atopic normal controls) and that this is related to disease severity as measured by the FEV1, methacholine PC20 and the symptom scores. (2) The cells expressing mRNA and protein product for CC chemokines include T cells, macrophages, epithelial cells, endothelial cells, eosinophils and mast cells. (3) CC chemokine gene-expression is related to the numbers of eosinophils infiltrating the bronchial mucosa. (4) There are different patterns of CC chemokine expression between atopic and non atopic asthma. Training content (objective, benefit and expected impact) The objective is to learn the methods of molecular immunopathology as they relate to the study of asthma. This is a growing and important disease in Europe and world wide. It will be possible to set up these techniques
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Edu*Select: Developing a Commercial Platform to Deliver Teacher Selection Tools' (EduSelect).

assistant: **Innovation**

Teacher selection presents a significant international challenge: UNESCO predicts that countries will need to select and train almost 69 million teachers by 2030 (UNESCO 2016). However, current teacher selection methods are largely ineffective (Goldhaber et al., 2014; Klassen & Kim, 2019), resulting in the suboptimal quality of the teacher workforce. Improving the ways in which prospective teachers are selected benefits children’s educational outcomes and a country’s social and economic health (Chetty et al., 2014). Our ERC-funded research (2015-2020) represents the first large-scale project to systematically develop and test a suite of selection tools using models from organisational psychology and medical education. Our results suggest that using innovative tools that are built on sound theory and research (especially using a situational judgment test [SJT] methodology) can reliably and validly assess the difficult-to-measure non-cognitive attributes of prospective teachers in multiple contexts (e.g., Klassen & Kim, 2018; Klassen & Rushby, 2019; Klassen et al., 2017; Durksen & Klassen, 2018). The goal of Edu*Select is to explore various commercial platforms (e.g., spin-out company, other start-up, licensing arrangement) from which to leverage our teacher selection research into widespread international application. The short-term impact of the proposal will be to establish the viability of commercial platforms from which to improve the ways in which education organisations (initial teacher education [ITE] programs and potential employers) can gather and use data to make decisions about selecting prospective teachers. The longer-term impact is the improvement of the quality of the teacher workforce, leading to social and economic benefits through enhanced educational o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Interplay among mitochondria and p53 family proteins during apoptosis induced by dna damage - a new strategy for cancer therapy' (IMPALED).

assistant: **Innovation**

DNA damaging agents (radiation and chemotherapeutic drugs) play a major role in the treatment of cancer. In tumours displaying high treatment sensitivity, these agents activate apoptotic pathways while resistant tumours show a blockade of these pathways. This project focuses on the analysis of the interplay between mitochondria and the p53 family proteins, sensors of DNA damage, in order to identify and verify new molecular targets responsible for therapy resistance of tumour cells. The main long-term goal of this proposal is to elucidate the mechanisms accounting for tumour resistance to killing, in order to allow the development of new strategies for cancer therapy. Research groups involved in this proposal have long track records in apoptosis research and are now joining efforts with a clinical partner engaged in exploring apoptotic mechanisms of treatment resistance in lung cancer. In addition, an industrial partner will join the project to provide genomic and bioinorganic capabilities and a route to commercial exploitation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Hybrid Commercial Vehicle' (HCV) under Seventh Framework.

assistant: **Objectives**

The HCV project aims to develop urban buses and delivery vehicles with advanced second generation of energy efficient hybrid electric powertrains in line with objectives in topic SST 2008.3.1.5. The final result will be the demonstration of a passenger bus and a distribution truck with this advanced technology. In addition early second generation buses and distribution trucks will be demonstrated in practical real-life conditions in different cities in the enlarged Europe in order to ensure good acceptance by public transport, delivery operators, drivers and passengers.Research, development and demonstration will be made of innovative e-drives, energy storage technologies as well as auxiliary components. In addition lightweight body technologies will be demonstrated. The decision to start vehicle production with advanced second generation technology will to a high degree be based on the outcome of the project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Child prodigies: on giftedness and child celebrities in modern France'.

assistant: **Concept**

Although there is no scholarly agreement on how to define “giftedness”, there is a consensus on why it is important: understanding giftedness, and especially, gifted children, means understanding human potential and development. Conceptions of giftedness affect education and parenting, and can create unrealistic expectations in adults and children. Child prodigies manifest an extreme form of giftedness. Research on giftedness is chiefly developed within psychology, and remains quite ahistorical. Meanwhile, historical research on prodigies focused on case studies, failing to account for today’s interest in gifted children.This project aims to go beyond these two approaches. It will explore how the history of child prodigies can help to explain the current fascination with giftedness. To do so, it will examine child prodigies in cultural and scientific settings (such as the theatre and the laboratory) in 19th and early 20th century France, mainly Paris. The project will address child prodigies as a cultural phenomenon that: a) influenced the western scientific interest in giftedness, and b) built a long-lasting entertainment culture around gifted children. The study will build upon past and current psychological research on giftedness, and contribute to fields such as the history of science, and childhood and celebrity studies. With my postdoctoral experience in an ERC project, and with a promising track record, I am prepared to move a step further. The MSCA will help me improve my skills in teaching and project management. In addition, I will be able to provide a historical background to a socially sensitive and timely topic. Overall, it will solidify my career, preparing me to apply for funding and academic positions to reach independence.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Analysis and control of ultrafast photoreactions in solids' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

The applicant will be trained in cryogenics, ultra fast spectroscopy, and condensed phase processes. Optical control and theoretical characterization of photoreactions and atomic dynamics are pursued using proper laser pulses and simulations, respectively.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'HydrOdynamics & biomechanics of canceR cell mIgration in heterOgeNeous media' in the context of a Horizon Europe call.

assistant: **Objectives**

So far medicine has not solved the workings of a formidable and scientifically challenging aspect of cancer: metastasis, the migration of circulating tumor cells (CTC) through the body. In this highly interdisciplinary project, expertise and techniques from fluid dynamics are employed to study how CTC move through the vascular network and what prompts them to do so.  The complex interplay among hydrodynamics, biophysics of intracellular interactions, and biochemical signaling within vascular networks is unknown. Our understanding of these underlying processes is hindered by the complex heterogeneity in the vascular network, comprising of capillaries, veins and arteries with a wide range of size and structural diversity.  To unravel these processes I bring my expertise in fluid dynamics and porous media together with the state-of-the-art facilities on experimental cancer mechanobiology and multiscale modeling at the host and secondment institutes.  I will conduct microfluidic experiments and simulations by simplifying the vascular network as strategically designed pore-network models. First, I will study the two-way interactions between the heterogeneous flow field and the deformable CTCs that control their overall transport, deformation and trapping. A heterogeneous flow field also induces a spatially nonuniform scalar concentration across the medium. CTCs are highly sensitive to certain biochemicals that can alter motility and invasiveness of CTCs. I will investigate how the local gradients of such biochemicals in a heterogeneous microsystem influence CTC migration. Finally, I will study the collective migration of CTC clusters through the system and quantify the dynamic intracellular interaction by measuring membrane tension and intracellular adhesion forces. These in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Improved Lifetime of Automotive Application Fuel Cells with ultra low Pt-loading' (IMPACT), addressing dissemination and exploitation.

assistant: **Impact**

The main objective of the planned project IMPACT is to increase the life-time of fuel cells with membrane-electrode assemblies containing ultra low Pt-loading (< 0.2 mg cm-2) for automotive applications. The economic requirements to reduce Pt loading leads to the challenge to maintain durability and performance, an aspect which has not been addressed sufficiently in public projects and studies. A durability of 5000 h under dynamic operation conditions with ultra low loading is envisioned for automotive applications. IMPACT aims at improving significantly durability in the automotive application at reduced PGM loadings by material development and MEA development. Development ist performed on the main  components of the cell, namely the membrane, the gas diffusion media and the electrodes. The basis for the durability is extensive testing at the industrial and research partner`s facilities under diverse and highly dynamic conditions and comprehensive and detailed analysis and evaluation of degradation processes and their importance for fuel cell performance loss. This analysis is utilized for the derivation of mitigation strategies by component modification and optimization of operation modes. The mitigation strategies are experimentally validated and consecutively lead to a demonstration of the improved durability in an predefined stack. IMPACT also aims at providing a cost analysis and an evaluation of the technical feasibility for large scale utilization of the project achievements. Recommendation and dissemination activities are planed within scientific workshops, publication of the results in scientific journals, and using project fact sheets.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Omi and technology in ADA and C for reliable safety critical hard real-time systems'.

assistant: **Objectives**

One of the major strategic goals of OMI is the development and industrial production of software and hardware tools. Focusing on the software components, the Architecture Neutral Distribution Format (ANDF) technology is identified as the key element for the minimization of the distribution cost of applications, not only inside the OMI community, but also beyond it. The project intends, first of all, to evaluate the performance of ANDF technology when it is used not only to retarget the language, but also the processor environment.In more detail: -· Extending the library of ANDF tools for safety critical applications: Special language features and safety critical requirements for the creation of embedded applications will be incorporated into producer and eventually installer. The currently available installers cover only widely spread microprocessors such as Intel 80x86, MIPS, and the like. In deeply embedded applications, derivatives of these chips are normally used, being microcontrollers rather than microprocessors. The workplan comprises installer development for specific controllers for embedded systems such as SAB 80C167, named ST10 at SGS-THOMSON. The developed installer will also have specific features for safety critical applications. -· Application to hard real-time systems: Thomson-CSF will use this technology to improve their current and future development for vetronics braking systems, including reliability analysis. A factor of major importance is that these applications are safety critical, so that the feasibility and superiority of ANDF technology in this context will be demonstrated. -· Extending the OMI/Tools Set: Advanced Informatics will develop a methodology and implement the appropriate algorithms in order to support safety and reliability analysis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Social Landscapes as Multicultural Spaces: Stećci in Bosnia and Herzegovina' (SOLMUS) under Horizon 2020.

assistant: **Objectives**

Stećci, the medieval tombstones, are expressions of religious belief, identity, politics and social ideology. They synthesise the historical, chronological, cultural and religious components of the medieval Western Balkans. There are over 60 000 stećci scattered around Bosnia and Herzegovina (BiH), the country that epitomises long-standing plurality. Through these monuments identities were enunciated, thus offering a rare opportunity to investigate the archaeo-historic growth of medieval SE Europe. SOLMUS adopts an innovative and interdisciplinary approach to study medieval funerary archaeology, with the aim to understand the social life of medieval Bosnian society that left us stećci. SOLMUS will model ‘inter/intra group’ interactions in medieval BiH by integrating principles from landscape archaeology, remote sensing, digital humanities, and the scientific and theoretical approaches of social archaeology with medieval iconography and epigraphy, therefore bringing an entirely new understanding of European medieval archaeology. The proposed project will synthesise complementary datasets from the archaeological and historical record, often treated separately. By defining the Past as shared, complex and nuanced, can archaeology stimulate new narratives for social integration? What was/is the regional impact of the peripheral East and the role of multiculturalism on the European Past? Dr Čaval is an experienced researcher, focusing on the archaeology of religion, historical archaeology and cultural astronomy. She will enhance her research and employability through training in theoretical, methodological and practical knowledge in social archaeology, as well as skills in SNA, RTI and GIS analyses (beneficiary), and medieval epigraphy and iconography (secondment). By bridgin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Innovative Technologies for an Engaging Classroom' to be submitted under Seventh Framework.

assistant: **Abstract**

iTEC is a large-scale pilot involving up to 1,000 classrooms focused on Learning in the 21st Century and the design of the future classroom. Partners include 15 Ministries of Education, leading ICT vendors, innovative SMEs, TEL researchers, teacher educators and experts in school validations and pedagogical evaluation. The key aim is to develop engaging scenarios for learning in the future classroom that can be validated in large-scale pilots and subsequently taken to scale.<br/>iTEC produces meaningful pedagogical scenarios (assisted by semantic web technology) for the future classroom and, from these, derives learning activities and new approaches to assessment that engage teachers, learners and stakeholders outside the school.  These are then tested and evaluated in the largest pan-European validation with schools yet undertaken.<br/>The iTEC technology approach will make the technical components, (people, tools, services and content) required by the scenarios, interoperable and discoverable, so that teachers can more easily select and combine relevant components tailored to the future classroom scenario of their choice. This is in line with current trends in which teachers can choose from a wide variety of loosely coupled tools and where interactive whiteboards and other interactive, multi-touch technologies may be acting as a 'gateway' for teachers to start exploring the further use of digital technologies in their classrooms.<br/>Combined with this, iTEC will research the skills and competences needed by teachers in the future classroom and equip teachers, both within and beyond the project, with the pedagogical knowledge and skills needed to implement project scenarios.<br/>Having identified scenarios with the maximum potential to have a transformative effect on