RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'SYNergize: Understanding spore-forming gut bacteria biology to target pathogens' (SYNergize).

assistant: **Concept**

Our intestinal microbiota consists of a dense community of microorganisms, highly adapted to the human gastrointestinal tract. Shared species between individuals indicates the presence of evolved and efficient transmission routes that ensure colonisation of beneficial bacterial species. Research has traditionally focussed on blocking enteric pathogen transmission routes as a means to prevent disease. However, a greater focus on understanding the transmission routes of commensal gut bacteria is required to promote health. Spores are resilient structures that maintain bacterial integrity in a dormant state for extended periods. My previous work has shown that spore-formation is a prevalent phenotype in the intestinal microbiota that promotes transmission of anaerobic gut bacteria, by maintaining viability in adverse aerobic environmental conditions until ingested by a new host. However, despite its importance, sporulation processes in commensal gut bacteria remain poorly understood.SYNergize will characterise the metabolic capabilities of gut spore-formers, spore composition and the environmental cues involved in spore formation and germination. By identifying combinations of bacteria and nutrients that inhibit enteric pathogens, SYNergize also seeks to provide new approaches to target the problem of increasing antimicrobial resistance in European healthcare systems. These probiotic isolate and prebiotic nutrient combinations can be used to create ‘synbiotics’, rationally designed and ingested to decolonise gut pathogens. A deeper understanding of sporulation processes could also allow spores to be used to effectively deliver anaerobic probiotic bacteria to the gut. By exploring transmission and colonisation processes of intestinal spore-forming bacteria, SYNergize seeks
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Cellular bioengineering by plasmonic enhanced laser nanosurgery' to be submitted under Seventh Framework.

assistant: **Abstract**

The use of nanoscience technologies to either perform therapy or diagnosis at the cellular level is expected to revolutionize 21st Century medicine by opening new approaches to cure various illnesses. However, cellular bioengineering is technologically challenging and becomes feasible only when different scientific disciplines are combined together to provide advanced cellular level surgery tools. To this aim, nanosurgery (i.e., surgery on the nanoscale) employs ultrafast laser technology and/or nanoscience emerging technologies (nanophotonics, nano-engineering, plasmonics etc.) to perform cell or even nucleus surgery. The major advantage of the nanosurgery approach is the prospect to disrupt submicrometer-sized organelles within living cells or tissue without affecting the surrounding material or compromising viability of the cell or organism.In this context, we intend to apply and optimize a novel femtosecond laser technique for nanosurgery of cancer cells. The technique, named plasmonic enhanced laser nanosurgery, combines the advantages of two rapidly expanding research and technological fields, namely plasmonics and ultrafast lasers, to build a versatile tool capable of performing high throughput cell nanosurgery. The main innovative goal of the proposal involves optical fiber integration of the plasmonic nanosurgery tool towards in-vivo (i.e. living subject) applications. In-vitro cell transfection (i.e., introduction of siRNA through the membrane of breast cancer stem cells (CSCs)) is the specific nanosurgery application of the Light2NanoGene project. The latter, is driven by the remarkable ability of these undifferentiated cells within a tumor to self-renew and promote metastases. The successful transfection of the CSCs with siRNA will silence the expression of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Existence, stability and highest waves in 2D-surface water waves' under Horizon Europe.

assistant: **Concept**

This MSCA-PF action in analysis of partial differential equations will establish instability, existence of dimension-breaking solutions, and necessary and sufficient conditions for highest waves in nonlocal and fully dispersive two-dimensional surface water wave equations. The objectives of this project will be achieved by implementing three interconnected work packages, each addressing key mathematical challenges related to water wave models: (in)stability, existence, and highest waves. Through these work packages, the project aims to establish instability theories of 2D surfaces, explore the existence of two-dimensional surface waves, and investigate the formation of highest singular waves in nonlocal water wave models. The project is based at the Department of Mathematical Sciences (IMF), Norwegian University of Science and Technology (NTNU), Trondheim, Norway, with a three-month secondment at the University of Franche-Comté (UFC) in Besançon, France. We will also collaborate with external partners, who bring in expertise in spectral analysis, bifurcation theory, and the Nash–Moser method in water waves. The collaborations support the successful achievement of the project’s objectives and enhance the PI’s career development as an independent researcher. This proposal aligns with the Horizon Europe Work Programme by addressing challenges in the mathematical theory of water waves, advancing the state-of-the-art of nonlinear waves. In addition to the research outcomes, the project includes lecturing and supervising activities, dissemination of the results in conferences, and participation in outreach activities organised by the NTNU. The research will be carried out within the research group ""Differential Equations and Numerical Analysis"", at the same department, whos
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Acoustic-Flow Interaction Models for Advancing Thermoacoustic Instability prediction in Very low Emission combustors' in the context of a Horizon 2020 call.

assistant: **Objectives**

Gas turbines are an essential ingredient in the long-term energy and aviation mix. They are flexible, offer fast start-up and the ability to burn renewable-generated fuels. However, they generate NOx emissions, which cause air pollution and damage human health, and reducing these is an air quality imperative. A major hurdle to this is that lean premixed combustion, essential for further NOx emission reductions, is highly susceptible to thermoacoustic instability. This is caused by a two-way coupling between unsteady combustion and acoustic waves, and the resulting large pressure oscillations can cause severe mechanical damage. Computational methods for predicting thermoacoustic instability, fast and accurate enough to be used as part of the industrial design process, are urgently needed.The only computational methods with the prospect of being fast enough are those based on coupled treatment of the acoustic waves and unsteady combustion. These exploit the amenity of the acoustic waves to analytical modelling, allowing costly simulations to be directed only at the more complex flame. They show real promise: my group recently demonstrated the first accurate coupled predictions for lab-scale combustors. The method does not yet extend to industrial combustors, the more complex flow-fields in these rendering current acoustic models overly-simplistic. I propose to comprehensively overhaul acoustic models across the entirety of the combustor, accounting for real and important acoustic-flow interactions. These new models will offer the breakthrough prospect of extending efficient, accurate predictive capability to industrial combustors, which has a real chance of facilitating future, instability free, very low NOx gas turbines.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Fast and easy previsualisation for creative industries' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Previsualisation is an essential phase in the design process of narrative art forms and media such as film, animated series, and stage plays. The possibilities that digital tools bring to this phase of production are immense, allowing early visualisations that support making creative decisions with much lower cost of changes than at later stages of production. Yet these tools require trained skills that are not available in typical small- to medium-size productions.The goal of the first.stage project is to provide a toolset that brings the power of digital previs to productions in key application areas by being easier and thus cheaper to use: professionals can use these tools in practice immediately without large investment. This will make previs easier and faster, with significant benefits for production quality.The first.stage toolset will employ natural user interfaces that utilise innate abilities and existing skills of artists for key tasks in previsualisation. Visual elements can be selected from asset libraries via expressive commands, while physical media such as figurines or stage models can be integrated by 3D digitisation. Elements can be arranged and views defined by gestures. Characters, cameras, and scenes can be animated by demonstrating the desired behaviour in the style of performance animation. This functionality will be based on state-of-the-art asset libraries, engines and motion capture hardware.The novel approach to previs that first.stage takes will have a direct impact on Europe’s storytelling industries – from the film industry over tv /commercials to theatre and other stage productions. It will give key creative personnel – (art) directors, choreographers, and concept artists – more artistic hold over productions. Accessible previs tools will f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Romani Chords: Uncovering Romani Practice for Harmonic Accompaniment with Sonic, Visual and Ethnographic Analysis'.

assistant: **Innovation**

The phrase “Romani chords” (RC) encapsulates the distinctively lush harmonic language of Romani musicians in Slovakia. This musical feature is key to impressing non-Roma audiences and something Roma consider a root of their entire musical culture. RC are not merely a sonic phenomenon, though. They reflect long-established economic practices in Romani professional music-making, skills in creatively re-interpreting music of the surrounding non-Romani majorities, and a particular form of musical learning whereby folk knowledge passes from generation to generation. RomChords is the first project that tackles this phenomenon in its anthropological and ethnomusicological complexity. The project is an interdisciplinary investigation approaching RC as three types of data: a) sonic, b) visual, and c) ethnographic. The main ambition is to challenge the primacy of Western theories of harmony and to reconsider RC from the Romani perspective, unearthing how Roma themselves perceive, conceptualise and theorise their chords. The project aims to answer the following key questions: What role do RC play in the performance of Romani ethnicity? What is the significance of RC for Romani professional musicianship? How do Roma learn RC, and how do they innovate them? And what is the role of vision in learning and teaching RC? Action to address these questions is shaped by three specific objectives, which will be pursued through international and intersectoral cooperation between three participating institutions: I) Data collection concerning RC among Romani musicians in Slovakia (Institute of Ethnology and Social Anthropology, Slovak Academy of Sciences); II) Trans-disciplinary analysis of the data, employing methods of qualitative social sciences and computational (ethno-)musicology (Institu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'AI-powered pathological cancer diagnostics' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

MindPeak is an innovative start-up that builds diagnostic support tools for cancer diagnosis. Our Artificial Intelligence (AI) software analyses biopsy slides within seconds to find tumour regions and quantify tumour markers to prepare them for visual inspection by the pathologist. In 2018, the number of diagnosed cancer cases has grown to 18 million globally.Consequently, the demand for cancer diagnosis to determine appropriate treatment has never been higher. Cancer diagnosis nowadays is a very time-consuming process and depends heavily on the knowledge and experience of specialised pathologists. Unfortunately, the number of experts can no longer meet the quickly increasing demand. As a result, patients must wait longer than necessary for their diagnosis.To overcome this challenge, MindPeak provides solutions based on deep learning to support pathologists in their diagnosis. Patients benefit from increased accuracy and a faster turn around time of diagnosis as well as reduced costs. The key USP of our AI is its reliability in the clinical context with its variations across and within labs. Funding from the EIC Accelerator will help us with a successful and fast go-to-market of our solutions that cover crucial improvements for cancer patients. With our technology, we address the market for pathology with a current size of $17.3 bn worldwide and an annual growth rate of 6.5%.


**Keywords:** deep learning, machine learning, AI, cancer, pathology, biopsy, tumour, tumor, image, recognition, histology, histopathology
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Improved use of germplasm collections with the aid of novel methodologies for integration, analysis and presentation of genetic data sets' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Gene banks have been documenting enormous amounts of genetic material. In the near future a boost of new genetic information will be generated when the largecolllections will be fingerprinted for numerous molecular markers to get a detailed description of the diversity at the molecular level. The explosion of data will pose serious problems on data access and analysis. The proposed project will solve these problems. The consortium will develop and evaluate an integrative information system with many novel analysis methods. The result will be a better informative and cost-effective germplasm management and exploitation system forth benefit of agriculture at the EU and worldwide level. To achieve this, amulet-disciplinary consortium of world-leaders in (bio) informatics, statistical genetics, gene banks and marker technology was formed, and end-users from the international gene bank and breeding community were added.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Step by step commitments for energy saving' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

At present, energy conservation campaigns provide households with a general awareness but do not provoke large scale behavior changes.The main goal of the STEP_BY_STEP is to maximize the number of households in a given area that significantly change their behaviour at home. Desired behaviour change includes reduced electricity consumption and the investment in energy efficient products and/or high quality renewable energy products.Communication strategies involving direct contact are typically more effective on behavioural change than mass media campaigns. Thus, a system will be put into place to make individual door-to-door contact with 80% of the households in a given area.Contrary to traditional door-to-door canvassing, often seen as a one-shot deal, our project solicits targeted households regularly through email or by phone and accompanies them over a 20 month period towards the adoption of energy-saving practices.To reduce the attitude-behaviour gap, our system uses proven communication techniques that push towards action. Households are regularly encouraged to try new ecological gestures adapted to their level of motivation. Feedback is given and social norms are used.Community-based social marketing strategies will be used to encourage energy-related investment decisions. Households likely to take individual investment decisions will be motivated to take such decisions benefiting from economies of scale and facilitated by other households’ experience. Institutional partners will launch their energy saving interventions amongst 9000 households in 4 European areas that represent diverse populations and communities. French SME E3D will provide a behavioral strategy along with a web based system for behavioral change developed within a research project. Partnered la
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'International multi-stakeholder dialogue platform framing the responsible development of Nanosciences and Nanotechnologies (NS&T)' (FRAMINGNANO) under Seventh Framework.

assistant: **Objectives**

The FramingNano project will support the establishment of a multistakeholders dialogue on NS&T regulation and governance among the scientific, institutional, industrial communities, the broad public to articulate consensus and absence of consensus between the various stakeholders, sustain a European debate between them, and foster the development of a shared frame of knowledge, objectives, actions to define constructive and practicable regulatory solutions toward a responsible development of NS&T.  This action will lead to a proposal of a Governance Plan designing a deliberative process for the responsible development of NS&T at European level and beyond, including recommendations for future research, policy actions, and co-operative research processes over the years 2009-2013. The activity of the project will be articulated in 28 months and geared around 4 key actions: 1. Analysis and review of existing-proposed regulatory processes, identification of stakeholders; 2. collection and analysis of stakeholders positions and needs; 3. Development of an appropriate proposal of a Governance Plan; communication and dissemination of  information on the project and NS&T governance. Project website and Newsletter, a mid term international workshop, a final international conference, and national workshops will be organised. The project brings together 6 partners from 6 countries, covering all main European geographical areas (North, Eastern, Centre, South). Consortium partners have a long experience in NS&T, in S&T assessment, consultation processes, analysis of technological and societal issues, communication,  and liaison already established with many relevant stakeholders. The project will support the European Commission, EU policy makers and stakeholders in designing a Europe