RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Higher coherent coholomogy of Shimura varieties' (HiCoShiVa).

assistant: **Concept**

One can attach certain complex analytic functions to algebraic varieties defined over the rational numbers, called Zeta functions. They are a vast generalization of Riemann’s zeta function. The Hasse-Weil conjecture predicts that these Zeta functions satisfy a functional equation and admit a meromorphic continuation to the whole complex plane. This follows from the conjectural Langlands program, which aims in particular at proving that Zeta functions of algebraic varieties are products of automorphic L-functions.Automorphic forms belong to the representation theory of reductive groups but certain automorphic forms actually appear in the cohomology of locally symmetric spaces, and in particular the cohomology of automorphic vector bundles over Shimura varieties. This is a bridge towards arithmetic geometry.There has been tremendous activity in this subject and the Hasse-Weil conjecture is known for proper smooth algebraic varieties over totally real number fields with regular Hodge numbers. This covers in particular the case of genus one curves. Nevertheless, lots of basic examples fail to have this regularity property : higher genus curves, Artin motives...The project HiCoShiVa is focused on this irregular situation. On the Shimura Variety side we will have to deal with higher cohomology groups and torsion. The main innovation of the project is to construct p-adic variations of the coherent cohomology. We are able to consider higher coherent cohomology classes, while previous works in this area have been concerned with degree 0 cohomology.The applications will be the construction of automorphic Galois representations, the modularity of irregular motives and new cases of the Hasse-Weil conjecture, and the construction of p-adic L-functions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Dagstuhl Seminars in Computer Science' under Fifth Framework.

assistant: **Concept**

The Idea behind the Dagstuhl-Seminars: The International Conference and Research Centre for Computer Science Schloss Dagstuhl is devoted to the stimulation of research in Computer Science. The main objectives of the Centre are to support and to foster research in Computer Science on an internationally recognised level as well as to stimulate continuing education and knowledge transfer between scientists and practitioners in different areas of Computer Science. The Centre regularly organises high quality scientific workshops on special topics in Computer Science, the so-called Dagstuhl-Seminars. These Seminars are a meeting-place for scientists of an internationally approved rank in one specific area of Computer Science from all over the world. The Seminars shall contribute to the exchange of results, stimulate the communication between the scientists and inspire future research. They allow the researchers to present their new ideas and to discuss problems and future developments. Two or 3 scientists prominent in the field apply for a Dagstuhl-Seminar. The Scientific Directorate reviews these proposals and decides about the composition of the list of participants. The participation in a Dagstuhl-Seminar is only possible with a personal invitation by the Centre. The centre ensures that the participants of a seminar form a good mixture between academic and industrial scientists as well as a good balance between colleagues with a high reputation in the area and young researchers. The Seminars should not have more than 45 participants, and in most cases have between 40 and 50 participants. The Seminars usually last one week. According to the concept of the Research Centre, not only lecture and lodging rooms are available. The participants can make use of several meeting room
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Resistance of spruce to root and butt rot disease' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

This Research explores resistance to infection by Heterobasidion sop. in clones of Norway and Sitka spruce. Clones will be inoculated with H. animus, H. variorum or H. abietinum and the extent of pathogen growth and lesion development measured. Resistance of clones will be related to qualitative analysis of terrenes. QTL/AFLP maps will be used to determine molecular markers for resistance. Localising the accumulation of pathogenesis-related proteins and measuring rate of development of bark boundary and xylem barrier zones to infection will determine post-inflectional responses of clones. Resistance of wyvern to degradation by the pathogens will also be assessed. These data will be used to analyse inheritance of resistance, and to develop methods to predict inheritance of resistance based on experimentally determined markers.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'ERA-NET TRANSPORT' (2002-2006) targeting Sixth Framework.

assistant: **Abstract**

The ERA-NET TRANSPORT wishes to enlarge the existing consortium with two additional partners: Poland and Denmark, so the consortium in the future brings together 13 partners from 11 European countries with a total research funding of Euro 294 million p.a. The enlargement and the proposed supplementation of the work programme is based on the full integration of Poland and Denmark in the existing ERA-NET TRANSPORT activities thereby fulfilling the recommendation of Evaluation Summary Report" for the ERA-NET TRANSPORT proposal (No. 510223). The enlarged consortium with Poland and Denmark will not only enhance the potential scope for cooperation, but also contribute to the creation of the ERA through the proposed additional task "Setting up cooperative national transport research programming". Both countries are at the moment in a process of setting up or resetting their national transport research strategies and programming. In return, the resulting precise and validated feedback information will fertilise the modernisation of existing programmes and programming practices towards national contributions to the European Research Area. The full text of the proposal summary can be found in chapter B 1.2 and an elaborated text on the proposed Task 1.6 can be found in chapter B 7.7. The enlargement of ERA-NET TRANSPORT requires an additional grant to the budget of 697.904 ?. The additional funding is necessary to ensure a full incorporation of the new partners in the existing and supplementary activities of ERA-NET TRANSPORT. The continuously monitored project costs indicate that the existing budget of ?3.2 million just covers the costs of the existing programme and consortium and by no means will be able to sustain further activities and partners."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Tryptophan - trp - photophysics' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

Research objectives and content Tryptophan is a fluorescent aminoacid used as an internal probe to get structural and dynamical information about proteins. When embedded in an enzymatic structure, the presence of other aminoacids creates an environment which annihilates the fluorescence. The aim of this project is to develop a molecular model to improve our understanding of these effects and the elucidation of protein structure through tryptophan fluorescence studies. The photophysics of tryptophan and its analogue indole will be studied computationally to assess the physical processes which control the fluorescence quenching by radiationless decay (conical intersections), including the influence of the polarity and acidity of the medium as well as molecular quenching by energy transfer. Highly advanced computational methods (CASSCF, MMVB) partly developed at the KCL Quantum Chemistry Group will be used. Training content (objective, benefit and expected impact) This project will allow me to learn the use and practical application of highly advanced computational methods working with Prof. Robb, who has participated in the development and improvement of computational chemistry programs. Links with industry / industrial relevance (22) Enzymes are applied in industry as catalysts in synthetic chemistry and in protein engineering, and as biologically active components of washing powders. The results of this project will improve the protein structure elucidation and provide new possibilities for these applications.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Etude de l'apprentissage et de l'enseignement des concepts d'energie et de force en Greece et en France' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

This project is situated within the framework of teaching notions in energy and force in two European countries, Greece and France. It aims to better educate our citizens in environmental concerns and in energy use. The study is based on psychological, didactical, and epistemological analysis of the functioning of learner knowledge. The work will be carried out with students from ages 10 to 17, divided by age into subgroups. We will study students' prior knowledge concerning our everyday environment as well as their learning in teaching situations dealing with energy and force. We will construct these teaching situations in both Greece and France. Our results will permit us to propose teaching situations adapted to the country in question as well as to the students' level. This research will contribute to enriching an interactive learning computer environment that has already been experimented on in France.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Platform for Advanced Single Cell-Manipulation and Analysis'.

assistant: **Objectives**

Analysis of biological cells down to single cell resolution is a prospective technique in nearly all fields of life science research. In particular manipulation and analysis of single cells can open up a new dimension in cell biology, tissue engineering, drug development and diagnostics. The advancement of single cell technology as a whole requires tools and instrumentation to sort, transport and manipulate single living cells. Micro system technology with its sophistications can provide in this context capabilities far beyond today's methods.<br/>Therefore, this project aims to develop a single cell manipulator (SCM) micro instrument for inkjet like printing of single living cells confined in micro droplets of only 50µm size. Such a device can serve as a universal tool for manipulating cells in a non-invasive flexible manner. Within the project the SCM device will be applied to cell biological applications in cancer research and drug development to demonstrate and validate the performance of the device, as well as to establish a flexible platform for advanced single cell-manipulation and analysis (PASCA).<br/>In order to achieve these objectives crosscutting technological challenges have to be faced which can be overcome by integrating and interfacing multiple core technologies, only. Cutting edge bio-sensing technology like impedance spectroscopy and state of the art micro dispensing methods will be applied and combined with latest cell biological methods to establish the SCM instrument as multifunctional microsystem for cell manipulation. Through the highly innovative integrated approach and the validation within the PASCA platform the SCM instrument has excellent exploitation perspectives in multiple application sectors.<br/>Also the project structure as a whole sup
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Single cell genomic analysis and perturbations of hematopoietic progenitors: Towards a refined model of hematopoiesis' under Horizon 2020.

assistant: **Concept**

Hematopoiesis is an important model for stem cell differentiation with great medical significance.Heterogeneity within hematopoietic progenitor populations has considerably limited characterization andmolecular understanding of lineage commitment in both health and disease. Advances in single-cell genomictechnologies provide an extraordinary opportunity for unbiased and high resolution mapping of biologicalfunction and regulation. Recently we have developed an experimental and analytical method, termedmassively parallel single-cell RNA-Seq (MARS-Seq), for unbiased classification of individual cells fromtheir native context and successfully applied it for characterization of immune and hematopoieticprogenitors.Here, we propose to uncover the hierarchy and regulatory mechanisms controlling hematopoiesis bycombining comprehensive single-cell RNA-Seq analyses, modelling approaches, advanced functional assays,single-cell CRISPR screens, knockout models and epigenetic profiling. Exciting preliminary result show thatindeed our approach is starting to uncover the complexity of hematopoietic progenitors and the regulatorycircuits driving hematopoietic decisions. We will pursue the following aims: (i) Generate a refined model ofhematopoiesis by comprehensive single-cell RNA-Seq profiling of hematopoietic progenitors, (ii) validatethe predicted model by in vivo functional developmental assays and then (iii) test candidate transcription andchromatin factors uncovered by our model for their role in controlling progression towards various lineagesusing single-cell measurements combined with CRISPR screens. Together, our study is expected to generatea revised and high-resolution hematopoietic model and decipher the regulatory networks that controlhematopoiesis. Our methods and models
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Nanotechnology for advanced rechargeable polymer lithium batteries' under Sixth Framework.

assistant: **Concept**

Nano-particulate electrode materials, electrode materials modified by surface layers in the nm- range (core-shell materials) and nano-structured composite electrodes and electrolytes offer tremendous opportunities to overcome the limitations of current lithium polymer microbatteries, e.g. reduces transport limitations within the materials and to decrease the over-potential required for intercalation/deintercalation reactions. Intelligent composite electrodes require a well-designed spatial distribution o f the various components. Simple mixing does not create optimised percolation patterns of conductive additives or other functional components. Self- assembling of nano-particles on preconditioned surfaces can be used to create optimised 3-dimensional mult i percolation patterns by use of the binderless" Substrate Induced Coagulation (SIC).Li4Ti5O12 shows excellent capacity retentions at various C rates and temperatures with a better safety than common electrode materials. This compound in the form of nano-tubes and nano-fibres is characterised by extremely fast Li+-intercalation /deintercalation. Adequate electronic contacts for high-rate operation of these electrode materials can be made by SIC-coating. Increased volumetric energy density on the anode side can be achieved by replacing carbon-based materials by lithium storage metals and alloys as silicon-lithium composite. These alloys have a very high capacity of 570 mAh/g 1 per lithium and per silicon, up to 4.4 lithium.Lithium insertion/extraction on this material leads to an important volume variation, which causes a capacity fading upon cycling. To overcome this fading the active materials have to be in a nano state. A new separator generation can be designed with a nano organic-ceramic hybrid (O RMOCER). A polyme
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'High-fidelity Collaborative Perception for Small Unmanned Aerial Vehicles'.

assistant: **Objectives**

Over the past two decades, we witnessed impressive advancements in Robotics. Amongst the most disruptive developments was the demonstration of small Unmanned Aerial Vehicles (UAVs) equipped with onboard cameras conducting autonomous, vision-based flights without reliance on GPS, sparking booming interest in a plethora of use-cases, such as automation of drone delivery, and infrastructure inspection and maintenance. This led to the emergence of new algorithms, advanced sensors, as well as miniaturized, powerful chips, opening exciting opportunities for automating single- as well as multi-UAV navigation. Current solutions, however, lack greatly in robustness and generality, struggling to perform outside very controlled settings, with onboard perception constituting the biggest impediment.Working in this area for over a decade, it is troubling that despite dramatic progress, we still lack the technology to enable a UAV swarm to autonomously scan the seas for refugee dinghies or forest areas for wildfires, and to provide help in such dire situations. While, in principle, the core technology is the same across all use-cases, battling adverse conditions, such as wind, smoke, and degraded illumination, render the latter use-cases extremely challenging as they are time-critical and cannot be postponed until favorable conditions arise. Employing some of the currently most promising sensors, such as lidar, and advanced depth, thermal, event, and visual cameras, SkEyes proposes to address fundamental research questions to understand how to process and combine these heterogeneous sensing cues onboard a swarm of small UAVs. The goal is to achieve joint spatial understanding and scene awareness for effective autonomy in highly dynamic and realistic scenarios. Engaging such eyes in th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Effects of Complement Factor 3 on Antibody Production in Fish' (1998-2002), addressing dissemination and exploitation.

assistant: **Impact**

Development of fish vaccines, which is of great importance to aquaculture, relies on a thorough knowledge of the fish immune system. Marine perciformes, such as the gilthead seabream, are of considerable economical importance to European fish farming, but knowledge of their immune functions lacks well behind that of other cultured fishes. The first objective of the proposed research is to develop B cell lines for seabream, so that some key aspects of B cell function can be studied. Using the only unequivocal surface marker of B cells in fish, membrane immunoglobulin (mIg), B cells will be isolated and cell lines will be established according to methods proven successful for catfish. B cell responsiveness to LPS or mIg cross-linking will be tested by measuring the mRNA and protein levels of secreted (s) 1g and M19. The second objective is to investigate the involvement of complement factor 3 (C3), a central component in the complement cascade, in stimulating antibody production. Complement was shown to be an important regulator of humoral immune responses in mammals. Because fish display a wide diversity in complement factors, and complement is a major contributor to host defense in fish, studying the effects of C3 on antibody production is particularly exciting and may lead to new strategies for fish vaccination. We will study the effects of various C3 isoforms isolated from seabream in combination with mIg cross-linking or antigens on Ig mRNA and protein levels.