RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Ericoid mycorrhizas and carbon biogeochemistry in subarctic ecosystems'.

assistant: **Concept**

This project will investigate the role of ericoid mycorrhiza (ErM) as a driver of carbon dynamics in natural ericaceous ecosystems, which has never been done before. The urgent need to address the role of ErM in soil carbon sequestration and decomposition was called for by Read et al. (2004) and therefore this project is timely. A substantial amount of the carbon allocated by plants to the fungi is subsequently incorporated into the soil organic matter when the fungi decompose. In WP I the rate of carbon allocation to ErM will be quantified using mycorrhizal and non-mycorrhizal seedlings grown on Petri dishes under laboratory conditions. This will test the hypothesis that approximately 10% of net assimilated carbon is transported to the ErM. The effects of global change factors on long-term ecosystem partitioning of carbon to different soil carbon fractions, such as lignins and soluble phenolics, will be investigated in WP IV using a full factorial open top chamber experiment simulating global change factors. This will contribute to an improved understanding of the sensitivity of soil biochemical processes to environmental change. ErM are also strongly believed to have a key role in the decomposition of soil carbon in arctic and boreal ecosystems. In WP II and III it will be determined how ErM colonisation of host roots and temperature interact to affect the decomposition rate of lignin and soluble phenolics both under laboratory and field conditions. It is hypothesised that both increased temperature and higher ErM colonisation will increase decomposition rates with implications for the long-term carbon storage in soil. Altogether this project is designed to produce new and unique results on how ErM affect the main processes involved in carbon dynamics in boreal and ar
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Bioinspired Catalytic Metallofoldamers'.

assistant: **Concept**

Inspired by mimicking the characteristics of terpenoid cyclase enzymes, the goal of this proposal is to design new types of catalysts containing electrophilic transition metal centers that could simultaneously fold and activate polyunsaturated substrates promoting non-inherent cyclization modes. Our goal is unprecedented, although it is rooted on fundamental organometallic chemistry, in particular, on the known activation of polyunsaturated substrates by highly electrophilic transition metals. These unconventional cyclizations cascades challenge the paradigm that the intrinsic reactivity of the substrate is the relevant factor in carbocation-initiated processes and would provide access to large carbocyclic skeletons such as those present in taxol and ophiobolin enantioselectively in a single step under catalytic conditions. Although the initial work will be carried out with gold catalysts, a major goal of this research is to develop other general-purpose efficient chiral electrophilic catalysts based on zinc. To attain our goal, we will study more simple catalysts to delineate the factors that control the folding of polyenynes and polyenes. Thus, we will prepare new series of C2-chiral catalysts in which the stereogenic elements are close to the reaction site. Related C2-chiral systems will be generated by supramolecular hydrogen-bond pairing. A similar chiral arrangement could also be achieved by an intramolecular chiral anion translocation from the metal to a distant hydrogen-bond donor site. In addition, we will explore larger systems based on structurally well-defined metallic clusters to generate highly electrophilic chiral reactive sites. The folding and activation of polyunsaturated substrates will be studied first with a series of catalytic prototypes based on d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Industrial-scale plant-based protein production in a cell-free platform', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The companyLenioBio is a biotech company that develops and markets a novel, unique and proprietary protein production platform, ALiCE®, which enables protein-based therapeutics to become more accessible and affordable and specifically targeting the substantial but underserved class of ‘difficult-to-express (DTE) proteins’.LenioBio has developed a proprietary tobacco-based cell-free protein synthesis (CFPS) platform “ALiCE” with a higher yield (3 mg/ml) than any other eukaryotic cell-free system currently available (0.2 mg/ml) at a lower cost, while ensuring protein stability and activity.The goal of PEPPER is to bring LenioBio to a position of competitiveness and growth to be able to meet the current industrial demands of ‘difficult- to-produce’ proteins for various biotechnology sectors (e.g. pharmaceutical, and agricultural industries). To achieve this, LenioBio will scale-up the protein production capacity and yield to be able to produce proteins at an industrial scale using a semi- automated platform, while complying to GMP protocols and FDA/EMA regulations for biopharmaceuticals proteins.LenioBio’s mission is to offer a fully integrated protein production platform for pharmaceutical and biotechnology companies with the ability to scale along with our customers’ needs. LenioBio is developing the ALiCE® technology into the first eukaryotic cell-free production platform for any proteins. LenioBio launched its first product as a protein expression kit in 2018 under the name ALiCE® (Almost Living Cell-free Expression). Due to its sustainable competitive advantages, already within nine months, 8 of the top 10 biopharma companies  are customers, with more in the process of registering LenioBio as a vendor.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Creating Lively Interactive Populated Environments' to be submitted under Horizon 2020.

assistant: **Abstract**

The primary objective of CLIPE is to train a generation of innovators and researchers in the field of virtual characterssimulation and animation and help bringing Europe at the forefront of the field.Advances in technology are pushing towards making VR/AR worlds a daily experience. Whilst virtual characters are animportant component of these worlds, bringing them to life and giving them interaction and communication abilities requireshighly specialized programming combined with artistic skills, and considerable investments: millions spent on armies ofcoders and designers to develop video-games is a typical example.The research objective of CLIPE is to design the next-generation of VR-ready characters. CLIPE is addressing the mostimportant current aspect of the problem: making the characters capable of: behaving more naturally; interacting with realusers sharing a virtual experience with them; being more intuitively and extensively controllable for virtual worlds designers.To meet our objectives, the CLIPE consortium gathers the main European actors in the field of VR/AR, computer graphics,computer animation, psychology and perception. The project will expose young researchers to the state-of-the-art researchwork in the areas, allowing them to develop character simulation techniques beyond the current frontiers, such as: machinelearning to provide characters with new abilities based on examples, procedural animation techniques to design large-scalevirtual population of characters, perceptual studies to evaluate character simulation quality and communication abilities.CLIPE also extends its partnership to key industrial actors of populated virtual worlds, giving students the ability to explorenew application fields and start collaborations beyond academia. Finally, a thor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Technologies for geothermal to enhance competitiveness in smart and flexible operation' in the context of a Horizon 2020 call.

assistant: **Objectives**

Future energy systems will face serious operational challenges with system reliability due to fluctuations caused by progressive integration of solar and wind power. Reliable and sustainable energy sources that can be utilized in large parts of Europe and that are able to balance these fluctuations are needed. Geothermal energy has the potential to become an excellent source for both base and flexible energy demands, providing much lower environmental footprint than both fossil and biomass fuels, as well as much less risks and societal resistance than nuclear power. There are however some techno-economic challenges which needs to be addressed to facilitate highly flexible operation of geothermal power plants. In GeoSmart, we propose to combine thermal energy storages with flexible ORC solutions to provide a highly flexible operational capability of a geothermal installation. During periods with low demand, energy will be stored in the storage to be released at a later stage when the demand is higher. As this approach does not influence the flow condition at the wellhead, critical infrastructures will be unaffected under variable energy generation. To improve efficiency, we also propose a hybrid cooling system for the ORC plant to prevent efficiency degradation due to seasonal variations. Efficiency will be further improved by larger power plant heat extraction enabled due to a scaling reduction system consisting of specially design retention tank, heat exchanger, and recombining with extracted gases. The scaling reduction system has the potential to almost double power production of many medium enthalpy geothermal plants. Overall, GeoSmart technologies will drastically reduce geothermal energy costs, making it cost competitive with its fossil fuel-based counterparts.To
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Polygenic Adaptation across Space' to be submitted under Horizon Europe.

assistant: **Abstract**

Rapid advances in sequencing are making an unprecedented amount of genomic data available from diverse organisms. However, theoretical and statistical frameworks for analysing sequences lag far behind, yet are crucial for identifying functionally important regions of the genome and predicting their contributions to key traits, e.g., disease risk in humans, yield in crops and environmental maladaptation in endangered populations. While numerous tools of genomic prediction, notably Genome-Wide Association Studies (GWAS), have been developed in recent years, a common and unsolved challenge is to disentangle the effects of different evolutionary processes on genomic variation. In particular, genetic differences between groups of individuals may reflect either natural selection (typically on highly polygenic traits) or spatial population structure (i.e., limited exchange of individuals and genes between geographically distant groups) or both. Moreover, both selection and population structure generate correlations along the genome, making it difficult to pinpoint individual genetic variants that affect traits. To address these challenges, we will develop new theory (based on mathematical analysis and computation) to understand polygenic adaptation across space, focusing on how sequence variation is shaped by: (i) the genetic architecture of selected traits i.e., the numbers, effects and genomic distribution of variants influencing a trait (Aim 1), and (ii) and the spatial distribution of populations (Aim 2). We will build upon this to investigate if/how selection and population structure can be disentangled in GWAS, and how selection affects the power of GWAS and the portability of GWAS findings across different populations (Aim 3). Such theory is essential and timely- both f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Early Upper Palaeolithic personal ornaments and behavioural adaptations', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

EU-BEADS investigates symbolically mediated behaviour of Early Upper Palaeolithic modern humans through the study of personal ornaments. Specifically, EU-BEADS will focus on the Levantine region between 60,000 and 40,000 years ago. The goal is a better understanding of variation and standardisation in shell bead production and use, as well as establishing new criteria for identification of anthropic modifications of marine shell beads. To achieve this, EU-BEADS employs a range of state-of-the-art zooarchaeological and taphonomic methodologies in conjunction with newly learned analytical techniques namely finite element analysis, use-wear analysis and GIS. In addition, EU-BEADS aims to develop a new analytical method to improve quantification of human actions in the production of shell beadwork using geometrics morphometrics. The large shell bead collection of Ksar’ Akil (Lebanon) will serve as a case study. The high quality, multidisciplinary research results will contribute significantly to our knowledge of Early Upper Palaeolithic behavioural adaptations and of modern human symbolically mediated behaviours in general.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Non-invasive technology for remote screening and personalised therapy of sleeping disorders: EU piloting and commercialisation project' (PREDESA), addressing dissemination and exploitation.

assistant: **Impact**

Sleep apnea (SA) is not just a disease anymore, it is an epidemic affecting more than 500 million people globally. The number of SA patients is increasing rapidly, causing cardiovascular diseases, neurocognitive dysfunction, daytime sleepiness, motor vehicle accidents, etc.SA is treatable, but the screening and care is not accessible for most people. Still, over 80% of SA-suffering patients are undiagnosed. Currently, most of the SA diagnostics and therapy is based on complex and stationary technology, available only at clinical settings. Also, the current prevailing methods are invasive, expensive and unreliable. Waiting lists are long, nearly 40% of performed analysis fail and when once diagnosed, patients tend to ditch the treatment soon.Nukute has a solution. We introduce a telemedicine ready technology that exceeds the current state-of-the-art technologies in analysis reliability, cost, therapy functions and user comfort. It is an excellent addition to expensive, stationary and error-prone polysomnography analysis and enables to extend SA screening service to wider patients´ audiences for 90% lower cost.Our technology combines sensitive microphones and gravity-meters with advanced diagnostics software to identify and predict upcoming SA events. Our unique collar device can diagnose different types of sleep apnea by monitoring the patient´s breathing quality and the respiratory rate and profile. The integrated Therapy function is based on body conditioning. It sends small electric pulses to stimulate the throat muscles when apnea or snoring occurs, without waking up the patient. The HW is integrated with applications running on a smartphone, tablet or laptop.The technology is already tested successfully against clinical equipment in Finnish hospitals. As a direct re
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Underpinning sustainable ecosystem management of seaweed resources in africa: expanding the seaweed database'.

assistant: **Concept**

Despite its enormous coastline and burgeoning coastal populations, Africa has not seen major developments of a seaweed industry except in Tanzania and South Africa and recently in Mozambique. In fact, there seems to be a relative paucity of local knowledge of seaweeds despite the incredible biodiversity, which is particularly high on the east coast. In some areas, such as Namibia and the west coast of South Africa, up welling of cold water shows enormous potential for mar culture development if the right algae and management techniques can be found. There is also considerable potential for the extension of Eucheuma cultivation to other tropical and subtropical countries. The main objective of the present project is to aid and accelerate this process by developing the Seaweed Database, currently a nomenclature and taxonomic source, to include a full range of validated information under the headings of ecological, commercial and technological data,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Syntactic functionality of motion verbs in Italo-Romance' (SynFuMIR) under Horizon Europe.

assistant: **Objectives**

The project SynFuMIR investigates functionality in syntax by analyzing complex motion verb constructions in regional Italian. Functionality concerns various grammatical aspects of certain linguistic items that allow lexical units to be assembled together in more complex structures. Although it is a fundamental aspect of language, its nature has not been fully understood yet. Crucial questions to theoretical linguistics depend on our understanding of functionality. These questions will be tackled with new data from multilingual speakers. Syntactic functionality will be investigated by collecting new data via on-site fieldwork with speakers of Southern regional Italian, Sicilian, Calabrian, and Apulian (around 300 speakers in total). The considered constructions are restructuring, pseudo-coordination, and multiple agreement constructions. The main objective of the study is the development of a new theory of syntactic functionality based on the role of location as a syntactic element. My hypothesis is that location plays a crucial role in functionality and non-canonical argument structure. Other goals are language documentation and the investigation of language contact.By focusing on language contact between two or more extremely closely related languages that contain slightly different but comparable constructions, the involved grammatical features will be investigated in a new way compared to previous studies on the topic. Our understanding of language contact (micro-contact) and multilingualism (bilectalism) will also benefit from this study. Besides its contribution to grammatical theory, this project has also a social and cultural impact on speakers communities because of the engagement of Italian speakers about their dialects and the acknowledgment of regional Italia
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'metal-carbene complexes for the synthesis of molecular switches and devices' (ORGANOMETALLICSWITCH).

assistant: **Concept**

Considerable effort is currently being devoted to the miniaturization of electronic devices to the nanometer scale, ideally affording systems that operate on a molecular level.  Chemist’s contribution to this research area has thus far concentrated on the preparation of organic OR inorganic materials. For example, purely metallic GaAs and GaP nanowires have been constructed for semiconductor applications. While these materials show excellent electron mobility properties, their tuning potential is rather low. In contrast, organic semiconductors such as conjugated oligomers or polymers display promising properties, though their electron carrier properties are intrinsically lower than that of metallic materials. Organometallic species comprising tunable organic ligand moieties and transition metal centers featuring an enhanced electron mobility may combine the advantages of purely inorganic and organic materials and are therefore expected to be particularly useful as molecular units for the fabrication of new electronic devices.  The proposed research aims at identifying molecular switches based on mono- and multimetallic complexes and at their implementation in electronically active devices, thus creating intelligent materials. While organometallic chemistry dominates the highly synthetic first part of the project, the characterization and application of self-assemblies in molecular electronics clearly requires an interdisciplinary approach.