RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Breaking Tolerance - Combination of Virotherapy and Immunotherapy for Cancer Treatment' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

The aim of this project is to enhance the efficacy of a tumour killing virus and break tolerance within the tumour to induce an immune response against the primary tumour and metastatic deposits. The proposed strategy requires three steps. First, the tumour immunological microenvironment needs to be reset as tumours utilize a variety of mechanisms to escape host immune system. Here, we propose to use the chemotherapeutic agent cyclophosphamide to temporally deplete suppressor T cells and recruit new dentritic cell progenitors. Second, to kill cancer cells, we propose to systemically deliver the potent tumour-killing (oncolytic) adenovirus ICOVIR15, which replicates selectively in cancer cells with pRB pathway mutations. In order to favour anti-tumour immunity, the ICOVIR15 will be genetically engineered to express cytokines that have been shown to be useful to stimulate anti-tumour responses such as granulocyte-macrophage colony-stimulating factor (GM-CSF) and interferon-gamma (IFN-g). Moreover, IFN-g has also been shown to kill tumour-associated vasculature. The host group has been awarded with three “non-commercial” clinical research grants from the “Fondo de Investigaciones Sanitarias” of the Ministry of Innovation and Science of Spain to test ICOVIR5 in clinical trials. ICOVIR5 is being produced under Good Manufacturing Practices. If the novel GM-CSF or IFNg armed viruses show promising results at preclinical level, the host group will apply for other non-commercial research grants to test it in clinical trials. This project is also aimed at further developing the skills of the applicant in genetic engineering, virotherapy, immunology and working in different tumour models. The applicant would move from the UK to Spain. The applicant hopes to establish herself as an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Automated Polishing for the European Tooling Industry'.

assistant: **Objectives**

poliMATIC - Automated polishing for the European Tooling IndustryFor the manufacturing of tools 12 to 15 % of the manufacturing costs and 30 to 50 % of the manufacturing time are allocated to polishing. As current automated polishing techniques are almost not applicable on parts with freeform surfaces and function relevant edges like 95% of the tools, the polishing is predominantly done manually.Therefore the overall objective of poliMATIC is to strengthen the competitiveness of the European Tooling Industry by overcoming the current drawbacks of die and mould finishing by realizing automation in laser polishing and force controlled robot polishing. Both processes already achieve low roughness’s on flat surfaces. But the critical step to bring these demanding processes into production is the polishing of freeform surfaces. To achieve this, the following significant technological innovations are needed:(1) Process development to achieve a roughness of Ra=0.05 µm (laser polishing) / Ra=0.005 µm (robot polishing) on freeform surfaces(2) The development of a knowledge-based CAM-NC data chain to make the new technologies usable for end-users(3) The development of a new surface metrology framework for polished surfaces. Current measures are insufficient to express e.g. the visual impression of a polished surfaceLaser and robot polishing offer potential to strengthen the European Tooling Industry by a significant decrease of polishing costs (75%) and time (90%). In 5-7 years this will result in expected annual savings of manufacturing costs for tools of 150 Mio. Euros and in reductions of the time-to-customer by 27 to 45 %. The shorter time-to-customer will stimulate new demands. In conjunction with the decreased costs this will lead to a regain of world market shares and ther
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Development of a new kind of low cost polymer sensor for the environmental analysis' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

The aim of the project is to develop of a new kind of a low cost polymer gas sensor as a prototype for flexible environmental analysis. The main technical and economical aims are: 80% reduction of price, quick time responses, flexibility, sensitivity. The steps for the development are the following ones: The optimization of polymer - layersystems for the selective absorption of hydrocarbon and nitric oxyde- molecules for the application in chemical polymer - sensor - systems. The further development of sensorarrays and the creation of a  fuzzy logic" for " intelligent" sensor - systems for various and flexible application in environmental gas - monitoring ( especially heptane, octane, hexane, alcohol, terachlorethylene). The development of a sensorapparatus as a prototype with technical and economical advantages against usual systems: Higher selectivity, higher sensitivity, and quicker time - responses to poisonous gases, as well as easier adaption to various applications at very low costs of the hole system for the use in industry ( hydrocarbons ), and for controlling the air pollution at petrol - stations, labs, refineries, refuse dumps, chemical cleaning units... The research project initiated by SMEs of Europe, will enable a lot of companies in Europe to have access to low cost devices for environmental monitoring. The world market in different branches ( for instance industry sectors dealing with hydrocarbons, controlling of air pollution, chemical cleaning units, petrol stations, controlling of alcohol concentrations, labs, refuse dumps, refineries, cooling installations, groundwater renewing units...) is very high and estimated at about 400000 sensors per year. It will bring a competitive advantage for the European industry in a field with a huge potential. At th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Sustainable management of soil and groundwater under the pressure of soil pollution and soil contamination' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

Aiming at solution and prevention of actual and future environmental problems, EU policy resulted in many Directives concerning water and soil. Moreover, the Commission of the European Communities composed a paper Toward a Thematic Strategy for Soil Protection" and set up a tight time schedule. Despite of above-mentioned legislative efforts an effective EU-wide approach to the problem of site remediation and groundwater contamination is hindered by a number of problems described by the CLARINET Working Group on "Co-ordination of RTD on an European level". There is little synergy at EU level between national and EU RTD programmes, leading to a serious overlap of research projects and parallel expenditures and less efficient use of limited resources. The broad dissemination of project results through national RTD programmes at an European level is very modest and fragmented. The starting points of SNOWMAN-Era-Net are the questions: "What do we HAVE?" - The consortium will produce a sound overview on programmes and their contents and management in the field specified. "What do we WANT?" - A Vision Paper will define the goal of European research activities in this specific field of environmental research. "How can we GET co-operation NOW?" - Specification of next steps, short- and medium-term, preparing ground in order to implement and conduct a research programme. Suitable tools (like uniform evaluation criteria etc.) will be developed. Knowledge dissemination will be supported by a close linkage with the EUGRIS project. On this portal, all findings produced within SNOWMAN will be published and made available to a wider community. On interpersonal level, networking with the European Soil Policy Working Group or Cost activities will be maimtained. SNOWMAN will also agree on
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Unravelling species barriers of coronaviruses'.

assistant: **Innovation**

Human coronaviruses (CoVs) are distributed worldwide and cause a significant percentage of all common colds. Most of these viruses presumably emerged through zoonotic transmission, have adapted to the human host, and are now known to cause mild upper respiratory tract infections. However, the more recent zoonotic transmission of the highly pathogenic Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) have demonstrated the potential of coronaviruses to also cause highly severe human diseases and are associated with a high mortality. The precise mechanisms that allow coronaviruses to jump across species barriers are only poorly understood. ""COV RESTRIC"" aims to unravel species barriers of coronavirus infections and to uncover basic host cell mechanisms preventing a transmission across different species. We hypothesize that conserved restriction factors exist between different species which limit viral replication and which need to be overcome via viral evasion and adaptation strategies in order to establish a zoonotic infection. These may include the lack or genetic incompatibility of essential viral replication co-factors as well as the presence of antiviral restriction mechanisms. We will use two complementary genetic screening approaches to identify unknown coronavirus restriction factors. Once we have identified possible candidates, we will analyze them for their cross-conservation employing coronaviruses from different species, such as human, bat and camel virus isolates, as well as the respective primary cell culture material originating from the authentic host. This approach will help to rigorously define species barriers to viral transmission which should promote future development of preventi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Investigation of the aerodynamic interaction between wind-turbine rotor blades and the tower and its impact on wind turbine design' (1994-1998).

assistant: **Concept**

This project will investigate and develop software for the prediction of aerodynamic rotor-tower interactions which occur when the rotor-blades of a Horizontal Axis Wind Turbine interact with the disturbed velocity field of the tower. This project will study both upwind and downwind rotor cases. The objectives of the project are: - to quantify the extent of the aerodynamic effect of the tower on the rotor blades, - to develop accurate methods which are suitable for use by the industry to predict the effect, - to study means of alleviating the effect. The project will focus on stall controlled rotors since the major uncertainties occur in or near the stall regime. The technical approach to the study will link fundamental experiments, computational fluid dynamics, engineering models and validation by data obtained from operating HAWTs in the field. It will be carried out by a consortium of partners in five EU countries covering manufacture, operation, government and academic research. Experimental measurements of blade pressures and forces and of the disturbed velocity fields for both both two- and three-dimensional models of the interaction will be obtained at reduced scale from wind tunnel tests, in the latter case using a model twin-bladed turbine, and at full scale by analysis of blade pressure and force data from an instrumented 27m diameter twin-bladed turbine in the field. Existing Navier-Stokes (CFD) codes, (a) using primitive variables, (b) using a vortex basis will be developed to handle the interaction aerodynamics between a moving rotor and the fixed tower, first at model scale and then at full scale. The blade surface pressure and wake velocity data will be used to aid the development and validation of these codes. Engineering codes will be further developed
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Sustainable Irrigation water management and River-basin governance: Implementing User-driven Services'.

assistant: **Concept**

SIRIUS addresses efficient water resource management in water-scarce environments. It focuses in particular on water for food production with the perspective of a sustainable agriculture in the context of integrated river-basin management, including drought management. It aims at developing innovative and new GMES service capacities for the  user community of irrigation water management and sustainable food production, in accordance with the vision of bridging and integrating sustainable development and economic competitiveness.SIRIUS merges two previously separate strands of activities, those under the umbrella of GMES, related to land products and services (which address water to some extent), and those conducted under FP5/6-Environment and national programs, related to EO-assisted user-driven products and services for the water and irrigation community.As such, it will draw on existing GMES Core Services as much as possible, by integrating these products into some of the required input for the new water management services.It also makes direct use of the EO-assisted systems and services developed in the FP6 project PLEIADeS and its precursor EU or national projects, like DEMETER, IRRIMED, ERMOT, MONIDRI, AGRASER, all addressing the irrigation water and food production sectors, some of which have resulted in sustainable system implementation since 2005.SIRIUS addresses users (water managers and food producers) at scales ranging from farm, over irrigation scheme or aquifer, to river-basins. It will provide them with maps of irrigation water requirements, crop water consumption and a range of further products for sustainable irrigation water use and management under conditions of water scarcity and drought, integrated in leading-edge participatory spatial online Decisio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'High-performance Independent Platform for low-cost big data ProJects' (HIPPJ).

assistant: **Concept**

Cherrydata, a software house focusing on big data & analytics applications, has developed the core engine of a native multi-model databasesystem designed to address the scalability requirements and economic constraints of big data projects. CherryTable, the core engine of Cherrydata’s multi-model database, has been benchmarked against the best state-of-art low-latency databases and, overall, CherryTable’s economic efficiency (cost-performance ratio) is 40 times higher, roughly corresponding to 10 years of Moore’s law. More and more, companies rely on cloud providers for efficient data management. Technically, this has been achieved through innovative on-disk indexing algorithms, as well as low-level optimization of disk access and memory usage; the combination of such factors has enabled outstanding write and read performance on commodity hardware, where competitors usually fail in one of the two.CherryTable will be positioned as a solution that can be installed on anycloud or on premises, without lock-in and with standard APIs to store and retrieve data. CherryTable’s favourable economics can be appealing not only for large global companies, but also for smaller national enterprises. For smaller companies, the outstanding performance of CherryTable represents an enabler for a variety of big data use cases and a key to unlock measurable and positive business benefits from the most important big data & analytics applications.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Stimulating Innovation for Global Monitoring of Agriculture and its Impact on the Environment in support of GEOGLAM (SIGMA)', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

By 2050, global agricultural productivity will need to increase with at least 70%. In order to guarantee food production for future generations, agricultural production will need to be based on sustainable land management practises. At present, earth observation based (global) crop monitoring systems focus mostly on short-term agricultural forecasts, thereby neglecting longer term environmental effects. However, it is well known that unsustainable cultivation practises may lead to a degradation of the (broader) environment resulting in lower agricultural productivity. As such, agricultural monitoring systems need to be complemented with methods to also assess environmental impacts of change in crop land and shifting cultivation practises. It is thereby important that this is addressed at the global level. SIGMA presents a global partnership of expert institutes in agricultural monitoring, with a strong involvement in GEO and the Global Agricultural Geo-Monitoring (GEO-GLAM) initiative.  SIGMA aims to develop innovative methods, based upon the integration of in-situ and earth observation data, to enable the prediction of the impact of crop production on ecosystems and natural resources.  The proposed project will address methods to: i. enable sharing and integration of satellite and in situ observations according to GEOSS Data CORE principles; ii. assess the impact of cropland areas and crop land change on other ecosystems; iii. understand and assess shifts in cultivation practises and cropping systems to evaluate impacts on biodiversity and the environment.  Furthermore, dedicated capacity building activities are planned to increase national and international capacity to enable sustainable management of agriculture. Lastly, a strong coordinating mechanism will be put in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'European Thematic Network for unlocking the full potential of Operational Groups on alternative weed control' (Oper8).

assistant: **Innovation**

Oper8 will set-up a self-sustainable, multi-actor, EU-wide Thematic Network to support and promote solutions for non-chemical weed control by building upon the knowledge and outcomes of 8 Operational Groups 7 countries, and stimulate knowledge exchange among all relevant actors and stakeholders. With the ambition to achieve a high impact and improve the sustainability of the European agricultural sector, the synthesis of partner OGs is based on their expertise, geographical location, novelty of solutions, as well as the established connections with the AKIS actors. Special emphasis has been placed on collaboration schemes among these OGs that progress at a different pace providing the opportunity to learn from the ‘early birds’, which will bring hands-on experience. The project will follow a multi-actor approach, implement a bottom up and top down model and build upon co-creation & cross fertilisation activities to help farmers access up-to-date knowledge, tools and techniques, applicable to specific conditions and needs.To this end, Oper8 will: (i) establish a stakeholder engagement processes to assemble the 7 National Networks (NNs); (ii) capture the drivers, barriers, and root causes of lack of non-chemical weed control adoption as part of a bottom-up approach; (iii) establish cross-fertilisation activities within and between the NNs to co-create, showcase, and evaluate non-chemical weed control methods; and (iv) deploy knowledge transfer tools and techniques (workshops, demo farms, CAP Measures) to adapt and scale up alternative weed control solutions and ensure their diffusion across EU. A series of actions (e.g., demonstration activities, policy recommendations and training sessions) for integrating project results into the CAP National strategic plans will be imp