RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Fatigue life assessment of additively manufactured material through a hybrid framework' (FLAME).

assistant: **Concept**

Additive manufacturing (AM) has been proven as a likely potential alternative to conventional manufacturing methods as it is able to reduce the global environmental impact of many industrial products. One of the main obstacles that prevent AM from expanding its application towards fulfilling the requisites of sustainability and green manufacturing, is poor fatigue resistance of AM material caused by multiple intrinsic surface and internal defects. Currently, different post-processing treatments are being used to tackle this challenge by enhancing surface regularity and reducing bulk defects. Despite the enhancement of fatigue resistance after the aforementioned treatments, these are additional steps that result in longer production times and higher costs. Moreover, due to the complexity of geometry and size, sometimes AM components cannot be easily post-processed by regular treatments. Optimizing the AM processes aiming at maximized fatigue life is a plausible solution that significantly minimizes the need for post-processing. However, the main barrier here is the lack of accurate, fast, and economic prediction tools to correlate fatigue life directly to AM process parameters. FLAME will address the aforementioned needs and pave the way towards efficient fatigue life assessment of AM via developing a hybrid framework through the association of physics-based models and machine learning approaches. It will improve the state-of-the-art fatigue life prediction accuracy from 75% to 90%, making them more economical by eliminating experiments and fast with an implementation time of less than 1 minute. FLAME, through its aforementioned performance, will effectively maximize the fatigue life at the design stage which results in a reduction of post-processing demand and a decreas
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'An Innovative and Energy-Efficient Radio Frequency Pretreatment on Emerging Micropollutants and Transformation Products in Anaerobic Sludge Digestion for Waste Reuse' (RADIOFREPOLIS) under Horizon 2020.

assistant: **Objectives**

Sludge management in wastewater treatment plants is still one of the most pressing issues due to dramatic increases in sludge production, disposal costs and increasing stringent regulatory restraints. As the most sustainable and cheapest disposal option, agricultural use of biosolids is encouraged as a part of a resource recovery solution by turning waste into a key resource. Anaerobic digestion is a common practice for sludge stabilization as an energy-efficient process before the beneficial reuse of biosolids. However, presence of the emerging micropollutants such as pharmaceutical and personal care products is creating potential human and environmental health threats despite the technological advancements in anaerobic sludge digestion. Europe needs to take immediate action for solving this issue; to safeguard the Union's citizens from environment-related pressures and risks to health and wellbeing within objectives of the EU 7th Environment Action Programme. RADIOFREPOLIS intends to investigate the occurrence and transformation of target pharmaceutical and personal care products by applying an innovative and energy-efficient radio frequency sludge pretreatment followed by anaerobic digestion as the first time in the literature for moving towards non-toxic environment. Proposed solution will reduce the uncontrolled release of micropollutants into the environment via sludge as well as reducing the quantity of excess sludge, improving the quality of sludge and increasing renewable energy to obtain a positive energy balance of the overall process, which will contribute to competitiveness of Europe. RADIOFREPOLIS will transfer knowledge on this newly acquired custom-built radio frequency heating technology to Europe and develop a novel project with multidisciplinary colla
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Reduction of co2 emission by means of co2 storage in coal seams in the silesian coal basin of poland (management of ghg emissions) recopol'.

assistant: **Innovation**

In this project the feasibility of greenhouse gas emission reduction by CO2 storage in subsurface coal seams is studied. Locally produced CO2 or flue gas from a power plant is injected in the coal at a selected test site in the Silesian Coal Basin (Poland), while CH4 is produced simultaneously. The CH4 can be used as fuel for clean energy generation, without net CO2 emissions. Research is mandatory in this new and complex field of technology to design an optimum development plan for the site. This research involves laboratory work, model simulations, and investigation of time-lapse monitoring. Existing wells at the test site and a newly drilled well will be used for the test, and the injected gas is monitored in time. Together with an evaluation and field up scaling of the results the project will be concluded with a socio-economical and a future technological evaluation, and implemented in a Decision Support System.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'IRC Flanders, providing high value technology transfer services' (2002-2006) targeting Sixth Framework.

assistant: **Abstract**

As many European regions, Flanders fails to convert its research efforts into commercially exploitable technology. IRC Flanders combines local and European networking to create opportunities for Flemish companies. IRC Flanders' objective is to provide cos t-effective and high quality transnational technology transfer (TT) services which answer to regional needs and which are provided in synergy with the regional support structures in Flanders. The main target for this contract is to increase the added value of the IRC in the process of transnational TT partner search in Flanders. The overall expected results are a gradual increase of TT activity in Flanders and more satisfied clients. To increase its reach, IRC Flanders will intensify co-operation with the l ocal innovation actors in the field. IRC Flanders will offer its transnational TT services to the Flemish innovation network, which groups all local innovation actors. The local actors are close to the companies, especially SMEs, and cover the entire Flem ish region. They are in a good position to determine local opportunities and requests. IRC Flanders will use its contacts in the IRC network to assist their clients for transnational TT. Via its co-operation with the actors in the Flemish innovation networ k, IRC Flanders has the opportunity to offer additional innovation services to its own clients. In addition to the local actors' awareness activities, IRC Flanders will specifically target companies involved in research activities. In terms of assisting clients, IRC Flanders will continue the activities developed over the past years. Continuous improvement of these services and better communication will increase customer satisfaction. The co-operation with the local actors will increase the number of cl ients. In
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Linking existing on ground, arrival and departure operations' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

The main objective of LEONARDO is to define and demonstrate the feasibility of integrating existing tools for arrival and departure planning management, together with those derived from the planning and routing function of the ground movement.One important goal will be to standardise as much as possible airport traffic management system integration and procedures at the European level, establishing a common model for integration and co-ordination of airport planning and management tools at the European level.The inclusion of two major airports with the integration of two technologies to fulfil a common set of user requirements will provide the opportunity to identify common requirements that can be achieved with different systems developed for airports with different necessities.The scope of the study will gain reliability based on the trials carried out at both airports, complemented with benchmark testing and quantitative measurements in an emulated environment.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Role of mTOR signaling dysregulation in the tumor suppressor networks in hepatocellular carcinoma' to be submitted under Horizon 2020.

assistant: **Abstract**

Hepatocellular carcinoma (HCC) is the predominant form of liver cancer and a leading cause of cancer death worldwide. Inactivation of different tumor suppressors, whose cooperation forms tumor suppressor networks, has been linked to HCC development, but the genetic events involved in HCC are still poorly understood. Mammalian target of rapamycin (mTOR) signaling is essential for cell growth and metabolism, and its hyper-activation plays an important role in pathogenesis and prognosis of HCC. However, the relationship between mTOR signaling dysregulation and the tumor suppressor networks in HCC, and whether mTOR inhibition could be a therapeutic strategy in some types of HCC remain largely unknown. Here I propose to use a genome-wide CRISPR knockout library to screen potential tumor suppressors in implanted mouse HCC models. The mouse hepatocytes depleted of different mTOR pathway components, with differential mTOR activities, will be separately infected with the CRISPR knockout library and implanted into immunocompromised mice to induce tumor. The goal of the proposed project is to understand the role of mTOR signaling dysregulation in the tumor suppressor networks in HCC. The specific objectives are: 1) to understand the tumor suppressor networks in HCC with differential mTOR activities in a genome-wide scale, 2) to examine how mTOR dysregulation controls the landscape of tumor suppressors, and 3) to explore whether mTOR inhibition could be developed as a treatment for specific subclasses of HCC. Using a combination of state-of-the-art CRISPR screening, molecular and cell biology, mouse models, next-generation sequencing, and bioinformatics tools, this project will link the mTOR signaling to tumor suppressor networks. This study will also unravel fundamental mechanisms
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Energy Performance Certificate Recast' in the context of a Horizon 2020 call.

assistant: **Objectives**

To reach the EU decarbonization objectives, it is urgent to trigger more investments targeting energy retrofit for buildings. Introduced at European level since 2002 within the Energy Performance of Buildings Directive (EPBD), Energy Performance Certificates (EPCs) represent a relevant instrument supposed to be strongly structuring for the assessment of buildings energy performance, decision support regarding energy retrofit projects, development and articulation of financing instruments (public and private), benchmark of building assets and market value recognition.  However, the potential for this instrument remains largely under exploited because of several challenges: The improvement in terms of reliability – referring to results variance depending on the assessor, input data and calculation tools, the lack of understanding between predicted and actual energy performance, etc. – represents a crucial issue to unlock confidence, decision support, and articulation for financing.   Besides, to engage end-users towards deep renovation, the certification is to structure tangible pathways to ambitious targets with respect to building overall quality and energy performance improvement.  Furthermore, the design for the overall process and certification outputs must be even more owner and occupant-centric and allow European benchmark and public policies analysis. To tackle the above challenges, and leveraging on the business operations of consortium partners, EPC RECAST will set a well-structured process and a toolbox supporting the development, implementation and validation of a new generation of Energy Performance Assessment and Certification, with a deliberate focus on residential buildings, more specifically existing ones, for which retrofit is one of the most challenging
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'artificial Intelligence To enHAnce Civic pArticipation'.

assistant: **Objectives**

ITHACA project aims to better understand the complexities and controversies for applying AI into the field of civic participation and stimulate new and responsible practices of research and innovation that anchor AI technologies design in human rights, values and principles, and moral and ethical reflection.The project vision is to contribute to the maximisation of the possible positive impact of AI on the functioning of democratic institutions and processes by developing and testing of a human centric Artificially Intelligent and Ethics by Design online discussion platform for civic participation in local governance, which incorporates human and social interpretations into the design process to ensure that AI decision-making processes are explainable, transparent and fair. ITHACA will pay particular attention to the needs and voices of citizens from vulnerable groups, with a view to ensuring that human rights impacts stemming from the design, development and ongoing deployment of algorithmic systems are comprehensively monitored, debated and addressed.Through its pilot activities in two different EU countries, ITHACA plans to assess the ability of AI to enhance citizens participation in the local governance while preventing or minimizing possible adverse effects stemming from unregulated use of AI and empowering citizens with knowledge about the AI model involved. ITHACA will also provide scalable tools for the identification of security risks and threats and for conformity with the Fairness principle and Privacy principle in AI-based systems and big data for civic engagement applications. Based on its implementation experiences, the project will define a data governance framework with relevant ethical principles and practices to be implemented in the design, developme
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'A data streaming platform to empower companies with intelligence through their entire business and value chains' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Activity Stream was established in 2015 in Iceland, to provide AI-enhanced data platforms, developing industry-specific functionalities. Our multidisciplinary and committed team of 28 people counts with over decades worth of experience developing online software solutions. In that way, we have already developed the Activity Stream (AS) platform for big data analysis. Our next milestone is to develop AS Exchange (Ase), a project that goes a mile further to solve the challenges that companies currently face to turn their data into timely actionable insights: 1) Raw data must be processed to have insights and it is a costly process 2) data from disparate sources is stored in siloes with little accessibility 3) such service for a secure information ecosystem currently does not exist in the market. ASe is the most complete data analysis system in the market: combines data integration, operation intelligence and an exchange solution, ensuring the maximum data value, going from raw data to actionable insights that can be shared across the business network. Our platform reduces 80% of the workload of a data analyst. Due to fast and timely actions can improve a 10% sales and 35% costs savings, ASe is a cost-efficient possibility for SMEs. Moreover, ASe is the only B2B solution in the market that provides the necessary trust, security and data ownership control to collaborate or monetize data-driven insights.AS platform has been already sold to some customers within sport and life-entertainment industry. With ASe we will now target new industries such as manufacturers and retail businesses, subject to complex supply chains; in this context, big players such as Nike are already waiting for ASe.  With ASe we bring a disruptive approach towards data analysis, taking us and Europe to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Exploiting plants for the production of future generation recombinant pharmaceuticals'.

assistant: **Innovation**

Biopharmaceutical proteins are typically produced in cultivated mammalian cells, a costly process with limited scalability. Thus products such as monoclonal antibodies are very expensive and often beyond the reach of the world’s poor. The problem is compounded by the fact that important strategies for preventing diseases such as HIV and rabies typically involve large doses of multiple antibodies and other virucidal proteins. Plants have emerged as alternative production platforms for biopharmaceutical proteins because they are less expensive, more scalable and potentially could be transferred to developing countries. Recently, the first products have reached the clinic, but many of them are follow-on products already manufactured in mammalian cells.Here, Prof Julian Ma (St George’s Hospital Medical School, London, UK) and Prof Dr Rainer Fischer (RWTH Aachen University, Germany) aim to develop innovative ways to use plants for the economical, safe and sustainable production of combinations of active pharmaceutical ingredients (APIs) based on recombinant proteins, thereby pushing the boundaries of what can be achieved in plants beyond current capabilities with fermenter-based systems.We will focus on the production of antibodies and lectins against HIV and rabies, with the aim of generating GMP-compliant microbicidal cocktails for evaluation in human trials. Key aspects of the project will include the production of APIs both individually and as combinations in plants, the development of technologies allowing the introduction of transgenes into pre-determined genomic loci, the use of click chemistry to optimize the production and stoichiometry of recombinant protein cocktails, the development of candidate products for both topical and parenteral administration and the deve
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'A compact / mobile and flexible system to reduce emissions and odours in off-gas' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

Due to new legislation both nationally and by the EC, there is a request for compact and / or mobile off gas treatment systems to treat both emissions and odours, for instance for chemical tanker ships, chemical storage companies, the chemical and the plastic industry. The objective for this project is to develop a system, which is multipurpose, flexible and uses a newly designed absorbent to meet the new legislations. The quantified goals are a reduction of 80% in odour and 70 - 95% in emissions. To reach these objectives a multi discipline team is proposed with knowledge on the manufacturing of off-gas treatment systems, olfactiometric / off-gas measurements and chemical specifics. End-users will have an important role in the project. The benefits for the EU are less environmental problems, less green house producing gasses in the air and more cooperation on EU level. The benefits for the joining companies are the opening of new markets and more cooperation on international level.