RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Investigation of the thermal,mechanical and electrical properties of foam' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

Research objectives and content The principle objective of the project is to achieve a basic theoretical framework for the mechanical, thermal and electrical properties of both aqueous and solid foams. The existing collaboration with Dr. Verbist and co-workers at SRTCA has already generated significant published research in the area of electrical conductivity and its application to foam monitoring in industry. The candidate has complimentary expertise in simulation software. The combination of computational modeling and experiment should prove fruitful in respect of: dependance of foam resistivity on liquid fraction; corresponding problems of thermal conductivity in solid foams; loacal mechanics of foam drainage; elastic/plastic/brittle mechanical response of solid foams. Training content (objective, benefit and expected impact) SRTCA is a major industrial, cross-disicplinary research centre having large scale computational and engineering facilities. A period of research here would provide invaluable training in the use of such large scale resources particularly the SP2 supercomputer. Since applications of this project will be of a materials science and engineering nature it will also involve substantial collaboration with workers in those fields. Links with industry / industrial relevance (22) SRTCA is keen to attain a complete understanding of the mechanical properties of aqueous foam in the context of such applications as enhanced oil recovery. Recent legislation on the use of CFC's in foam generation and the necessity of refining replacement materials have made it essential to understand the details of thermal conductivity in solid foams for use in insulation and refrigeration and the mechanical properties of polyurethane foam for automobile seats. The candidate's
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Molecular mechanism of LNP-mediated intracellular delivery of RNA'.

assistant: **Concept**

Lipid nanoparticles (LNPs) are promising for RNA delivery, yet their effectiveness is hindered by endosomal entrapment post cellular uptake, limiting their therapeutic potential. The challenge lies in the inadequate understanding of the endosomal escape mechanism. This project aims to comprehensively replicate endosomal escape in vitro, employing three objectives to explore LNP interactions with membranes and RNA translocation. Objective 1 focuses on understanding the impact of pH and LNP formulation on LNP/membrane interactions. Employing supported lipid bilayers (SLBs) mimicking endosomal membranes, the binding and fusion rates of distinct LNP formulations will be examined using total internal reflection fluorescence microscopy. This will highlight key factors influencing these interactions, which constitute the initial step of endosomal escape. Objective 2 aims to reconstitute RNA translocation across endosomal membranes using giant unilamellar vesicles (GUVs). These vesicles simulate endosomal conditions, enabling the visualisation of LNP-loaded RNA translocation across vesicle membranes via spinning disk microscopy and fluorescence correlation spectroscopy. This will offer direct evidence of the success of the second step of endosomal escape and insights into how various LNP formulations react to diverse pH conditions. Objective 3 introduces novel bifunctional phospholipids (BPs) into LNP formulations to facilitate visualising LNP fusion with endosomes in live cells through confocal microscopy. This technique also permits the visualisation of RNA release and subsequent protein expression. By addressing the endosomal escape challenge through innovative in vitro and cellular models, this project aims to unravel the complexities of LNP interactions with cellular barri
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Conformational studies of highly dynamic viral replication complexes' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Paramyxoviruses, including, measles and a number of dangerous human pathogens, are negative strand RNA viruses that express their own machinery for transcription and replication. Different interactions between the nucleoprotein (N) and the phosphoprotein (P) are essential for chaperoning and assembly of N on newly synthesized RNA genomes to form nucleocapsids (NCs), as well as for initiating replication and transcription. Both N and tetrameric P exhibit extensive conformational disorder, with very long, unfolded regions that host important post-translational modification sites as well as regulatory interactions with host and viral partners. The presence of this level of disorder, in viruses whose genetic information is normally so parsimoniously exploited, remains unexplained. The elaboration of time-resolved, atomic resolution descriptions of the interaction trajectories of these highly disordered N:P complexes is extremely challenging, requiring the development of adapted methodologies that can account for their intrinsic flexibility. The role of N and P has been rendered yet more enigmatic following our recent observation that when mixed in solution they form liquid-like droplets. Such membraneless organelles are revolutionizing our understanding of cellular chemical biology, although their physical basis is poorly understood. Our aim is to describe these important complexes at atomic resolution, in particular to understand the role of the extensive conformational dynamics of N and P in the replication cycle. Our recent success in engineering soluble N:P complexes from measles that assemble into NCs, combined with ongoing development of NMR-based methods to investigate the structure, dynamics and interaction kinetics of large, intrinsically disordered proteins, fluor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Protein biomarker for the prediction of response to endocrine treatment in breast cancer patients', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Classical pathologic parameters have been used to inform adjuvant clinical treatment choices for early breast cancer patients. There remain a significant number of patients however, who despite a reportedly favourable prognostic profile, experience metastatic disease.  Elucidation of the mechanisms of tumour adaptability and the identification of predictive markers of early recurrence is the basis of personalized medicine.  Work from our group has established the developmental protein HOXC11 as a powerful predictor of resistance to endocrine treatment in breast cancer patients .The aim of this project is to establish a joint industry-academia partnership to produce a commercially viable and clinically validated predictive assay/kit which based on the use of  HOXC11 as a predictive biomarker of poor response to endocrine treatment in breast cancer patients.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Advanced nitrogen sources electronic semi-conductor thin film fabrication' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Element III nitrides are very stable and direct large Element III nitrides are very stable and direct large band gap materials which are particularly well suited for high power microwave, high temperature electronics and UV/blue optoelectronic device applications. However, the realisation of nitride compounds requires the development of several enabling technologies to overcome today's limitations. The basic technology which is the today limitation is the growth process, while other technologies, such as processing, can more easily be transferred from existing methods. One of the bottleneck of the epitaxial nitride growth technology development is the absence of an efficient source of nitrogen active species. This is particularly true for extremely efficient ultra high vacuum (UHV) based fabrication technologies such as molecular beam epitaxy and related methods. The main objective of this project is to develop well adapted sources of nitrogen for the low temperature growth of element III nitrides using UHV technology. Only two complementary approaches can overcome the problems of atomic nitrogen sources and will be investigated: the use of plasma sources (electron cyclotron resonance (ECR) or radio frequency (RF) activated) and catalytic thermal cracking cell operating at relatively low temperature. Other correlated objectives are: i) the design and fabrication of an UHV dedicated nitride growth reactor optimising the use of the developed sources and ii) the establishment of the basic know how of the growth of a nitride MBE type process in order to be able to produce high quality nitride quantum well based electronic devices at a medium term. The ANISET project is divided into four technical workpackages (WP) corresponding to the main points considered:  WP1: Developme
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Volume changes associated with photoinduced proton transfer processes in biological photoreceptors' (1994-1998).

assistant: **Innovation**

Research objectives and content The best exampie of a biological photoreceptor acting as a proton pump is the bacterial pigment bacteriorhodopsin (BR). Photothermal methods such as temperature (T)-dependent laser-induced optoacoustic spectroscopy (LIOAS) and photothermal beam deflection (PBD) permit the determination of volume changes associated with the various steps of the light-induced process, in acqueous solutions at regular temperatures LIOAS studies with BR have shown that structural volume changes, AVR, occur in the ns time range; being followed by large changes in the u-and ms time ranges, as shown by PBD studies. Experiments with isomerizable dyes, models for the retinal chromophore in BR, indicated that the values of AVR result from a rearrangement of the solvation sphere in the photoisomerized chromophore. For photoinduced electron transfer reactions with Ru-cyano complexes, the AVR values were correlated with changes in specific solute-solvent interactions: To better understand the molecular origin of the AVR values, BR mutants in which amino acids have been exchanged, will be studied by T-dependent LIOAS and PBD, as well as model systems, such as various pH indicators in water, alone and with small polypeptides and lipids, both in regular and deuterated solutions Training content (objective, benefit and expected impact) The project will allow the candidate to carry out a postdoctorate research programme in the fields she has worked in during her PhD research training, namely photoactive molecules of biological interest. In particular the candidate will extend her skills in dealing with photobiological problems from a biophysical and chemico-physical point of view, with particular regard to primary molecular events triggered by the absorption of light and r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Super Dryer – Breakthrough clean fibrer dryer to cut emissions in paper production, urban sludge and clothes recycling' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

SuperDryer is a breakthrough clean fiber drying system to reduce energy use and GHG emissions in paper production, sludge processing and textile recycling. It will be the first fiber dryer to integrate renewable energy inputs, cutting GHGs to zero.It uses a patented closed-loop heat and moisture recapture system to recover 100% of heat, stop 100% of airborne emissions, and reduce energy use by 25% compared to existing dirty driers.TM Systems has 100+ experts developing innovative energy-saving equipment. Its installed technology already saves 1 nuclear power plant worth of energy annually.Initial customers will be pulp and paper mills and recyclers, with several interested buyers. Future customers will be municipal and industrial sludge processors, and textile recyclers.TM Systems has prototyped and validated SuperDryer. In this project it will pilot the first full-scale unit in a working paper mill and reach commercialization.


**Keywords:** Environmental and Green Technologies,Environmental protection
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'ADVANCED METAL HYDRIDE TANKS FOR INTEGRATED HYDROGEN APPLICATIONS'.

assistant: **Innovation**

ATLAS-H2 is an Industry-Academia Partnership on hydrogen storage in solid materials aiming to develop and test (in the short term) and bring to the market (in the medium to longer term) integrated advanced metal hydride tanks with high added value applications especially for stationary systems and hydrogen compression. Storing H2 without compression and energy losses is a challenge for the widespread use of hydrogen as energy carrier and the establishment of a hydrogen economy. Hydrides offer the best volumetric density for H2 storage, far better than storage in liquid state insulated reservoir or high pressure tanks. In a complete new process, thermal heat energy is stored within the metal hydride tank and is kept available for desorption with high insulating patented materials. The so called adiabatic metal hydride tanks are ideal for the storage of Renewable Energy, power peak shaving to stabilize electricity grid distribution, waste heat valorisation, but also transport applications as these new ternary alloy hydrides can feed directly fuel cells. On the other hand, compression of H2 using reversible metal hydride alloys offers an economical alternative to traditional mechanical hydrogen compressors. Hydride compressors are compact, silent, do not have dynamic seals, require very little maintenance and can operate unattended for long periods. When powered by waste heat, energy consumption is only a fraction of that required for mechanical compression, which reduces the cost of H2 production and storage. The simplicity and passive operation of the hydride compression process offers many advantages over mechanical compressors. The main ATLAS-H2 objectives will be achieved by implementing a well structured IAPP program between two high level European Research Institute
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Value-driven AI-enhanced Construction Waste Management'.

assistant: **Innovation**

Construction waste (CW) is a significant issue for environmental sustainability and economic efficiency. In the UK, construction, demolition, and excavation waste made up 62% of the total waste generated, amounting to 137.8 million tonnes​. Across the EU, construction and demolition waste represented the largest waste stream, with 374 million tonnes recorded. While recovery rates are high, much of this waste ends in landfills or is repurposed in low-grade applications, highlighting the need for improved recycling quality to better align with circular economy principles that advocate for the reuse and recycling of waste. Effective management of construction waste not only supports sustainable practices but also contributes to achieving the UN Sustainable Development Goals (SDGs), particularly SDG 12, which emphasises responsible consumption and production.Our research project is at the forefront of advancing sustainable construction by leveraging cutting-edge AI technologies and innovative waste magement strategies. The project aims to advance sustainable construction by leveraging AI technologies. It will precisely determine construction waste at the project level, identify waste generation points, and develop effective waste handling strategies. The project will also develop new KPIs for construction waste management to assess the efficiency of waste handling practices, resource utilisation, and project sustainability. Additionally, AI-driven decision-support systems will be developed to provide actionable insights for construction managers. The project emphasises sustainable construction practices, including materials reuse and building design for disassembly and reassembly. It will also establish guidelines, best practices, and policy frameworks to facilitate the ado
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Network-based Expert-Stakeholder Framework for Sustainable Remediation'.

assistant: **Concept**

The management of contaminated land has moved through different stages over the last few decades, each stage being characterized by a specific approach. The most recent stage is that of sustainable remediation, whereby decisions on the management of contaminated sites have to be sustainable across all the three pillars of sustainable development (environmental, economic and social). In particular, ensuring the social acceptability and support of remediation strategies and actions is currently regarded as being of high importance. The proposed research project aims to improve the development and assessment of sustainability in contaminated land management processes, through the development of an interdisciplinary framework for the integration of new social sustainability indicators with existing indicators of environmental and economic sustainability applicable to remediation projects. The development of this framework requires first the integration of expert and stakeholder-based assessments of social sustainability and the subsequent integration of the social assessments with environmental and economic indicators of sustainability. To achieve these ends, the project advances an original interdisciplinary approach that draws on social network analysis (from sociology), project ecologies (from economic geography) and multi-criteria decision analysis and sustainable remediation (from environmental science). The expected results are relevant for researchers interested in sustainable remediation, to policy makers, experts and consultants involved in contaminated site management as well as for site owners, local authorities, site neighbors and the interested public.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'High Integration of Research Monographs in the European Open Science infrastructure' (HIRMEOS).

assistant: **Innovation**

HIRMEOS will improve five  important  publishing  platforms  for  the  open  access monographs in the SSH and enhance their technical capacities  and services,  rendering  technologies  and  content  interoperable  and embedding  them  fully  into  the  European  Open  Science  Cloud. The  project focuses  on  the  monograph as  a significant mode  of  scholarly communication  in  the  SSH and  tackles  the  main obstacles  of  the  full  integration of  important  platforms  supporting  open  access monographs and their contents.  HIRMEOS will prototype innovative services for monographs in view of full integration in  the European  Open  Science  Cloud by  providing  additional  data,  links  and interactions to the documents, paving the way to new potential tools for  research  assessment,  which  is  still  a  major  challenge  in  the  SSH. The  platforms  participating (OpenEdition Books, OAPEN Library,  EKT  Open Book Press,  Ubiquity  Press  and  Göttingen University Press ) will be enriched with tools that enable identification, authentication and  interoperability (DOI,  ORCID, Fundref),  and  tools  that  enrich  information  and entity extraction  (INRIA  (N)ERD),  the  ability  to  annotate  monographs  (Hypothes.is), and  gather  usage  and  alternative  metric  data. HIRMEOS  will  also  enrich  the technical  capacities  of  the  Directory  of Open  Access  Books  (DOAB),  a  most significant  indexing  service  for  open  access  monographs  globally, to  receive automated information for ingestion, while it will also develop a structured certification system to  document  monograph peer-review. Partners  will develop shared minimum standards for their monograph publications, such that allow the  full  embedding  of  technologies  and  content  in  the