RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The normative dimensions of action and order - the economics of an inclusive europe' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

This project intends to contribute to the design of a broad approach to promoting the achievement of a more inclusive Europe. It addresses in particular the study of institutional conditions that may foster the participation of civil society to activities associated with the satisfaction of social needs. Dealing with the problems of social cohesion and inclusion in an economic perspective requires a critical appraisal of the prevailing concepts of action and order in our discipline. It involves, in particular, a re-discussion of the role of the normative dimensions in economic analysis. Bringing together different economic theoretical views on the issue of action and order, and combining historical, experimental and computational approaches, this project's team aim is to argue the importance of values and shared rules in economics, and to explore new ways to incorporate them consistently in economic theory and policy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Mechanisms of transport across biological membranes'.

assistant: **Objectives**

Living cells depend on the correct functioning of proteins that transport cargo across the membranes.  We will use computer simulations to understand the mechanisms employed by three proteins that mediate transport across biological membranes. Each of these three proteins is important for physiology and disease.A large part of the research planned aims at understanding the SecA motor protein. SecA is an essential component of the Sec translocation system in bacteria, where it couples the hydrolysis of adenosine triphosphate (ATP) with remarkable protein conformational changes to transport newly synthesized proteins across the plasma membrane. Key open questions concern the mechanism of the chemical-mechanical coupling employed by SecA, and how SecA works together with the SecYEG protein channel to translocate proteins. We will address these questions by performing molecular dynamics computations at the classical and combined quantum mechanical/molecular mechanical levels, and bioinformatics analyses.The plasma membrane proton pump is a member of the P-type ATPases family, complex enzymes essential for maintaining the plasma membrane potential and for secondary transport systems in eukaryotes. We will assess the dynamics of the AHA2 plasma membrane proton pump in a hydrated lipid membrane, the mechanism of long-distance conformational coupling, and the functional role of specific amino acids.Channelrhodopsin-2 is a light-gated cation channel that can be expressed in mammalian neurons and used as a powerful tool to probe neuronal circuits. Comparison of the sequences of channelrhodopsin-2 and other microbial-type rhodopsins raises intriguing questions about the functional roles of specific amino acids. To  contribute to the general understanding of the principles that gov
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Scalable Similarity Search', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Similarity search is the task of identifying, in a collection of items, the ones that are “similar” to a givenquery item. This task has a range of important applications (e.g. in information retrieval, patternrecognition, statistics, and machine learning) where data sets are often big, high dimensional, andpossibly noisy. State-of-the-art methods for similarity search offer only weak guarantees when faced withbig data. Either the space overhead is excessive (1000s of times larger than the space for the data itself),or the work needed to report the similar items may be comparable to the work needed to go through allitems (even if just a tiny fraction of the items are similar). As a result, many applications have to resort tothe use of ad-hoc solutions with only weak theoretical guarantees.This proposal aims at strengthening the theoretical foundation of scalable similarity search, anddeveloping novel practical similarity search methods backed by theory. In particular we will:- Leverage new types of embeddings that are kernelized, asymmetric, and complex-valued.- Consider statistical models of noise in data, and design similarity search data structures whoseperformance guarantees are phrased in statistical terms.- Build a new theory of the communication complexity of distributed, dynamic similarity search,emphasizing the communication bottleneck present in modern computing infrastructures.The objective is to produce new methods for similarity search that are: 1) Provably robust, 2) scalableto large and high-dimensional data sets, 3) substantially more resource efficient than current state-ofthe-art solutions, and 4) able to provide statistical guarantees on query answers.The study of similarity search has been an incubator for techniques (e.g. locality-sensitive hashing a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Modelling evaluating and formalising interactive systems using tasks and interaction objects' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

The aim is to develop a method with associated tools and techniques for engineering the design, development and evaluation of user interfaces for ATC systems. The method will be applicable to other safety critical systems.The proposal is addressed to capture usability and safety user requirements for ATC applications and to show how it is possible to check their satisfaction at both formal specification and implementation levels. The proposal has three main objectives: A method which allows designers to develop ATC user interfaces specifications and related software implementations which satisfy usability and safety requirements. The method will be supported by a set of automatic tools which will allow designers to address large size, with industrial relevance, case studies. The development of ATC user interfaces prototypes which will be validated against usability and safety requirements by formal specification and empirical testing. The Mefisto project will contribute to the design of user interfaces for safety critical interactive systems with special reference to Air Traffic Control (ATC) applications. With the predicted increases in volume of air traffic into the next millennia, software solutions to the problems of air traffic control workload are attractive. Motivations:Air traffic forecasts are normally based on passenger demand and economic factors, through the assumption that there is no limitation in the air traffic system itself, but it is obvious that there are constraints limiting the expansion of the number of flights. The number and the duration of delays, especially during peak hours (estimated to an annual 2 billion dollars cost) show that the ATC system and the airports are not always able to cope with the demand. This growing air traffic increases th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Evaluation of non destructive testing techniques for monitoring of material degradation' (GRETE) under Fifth Framework.

assistant: **Objectives**

The lifetime extension of aging power plants for electricity production is an economical way to reduce the cost of the kilowatt-hour for the benefit of the customers. Extending the lifetime of existing installations requires the development of innovative techniques for the inspection of critical components. Such techniques will detect changes in the materials and allow to plan the actions for failure prevention: change of operation parameters, increased inspections or replacement of components. The aim of this project is to assess the capability and the reliability of these techniques by means of an evaluation concerning irradiation damage in reactor pressure vessels and thermal fatigue of pipings. Series of aged samples will be characterised metallurgically and mechanically before being tested by the partners using various non-destructive techniques.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Managing Alternatives for Privacy, Property and INternet Governance' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Building on the results of several EU FP7 projects including CONSENT (covering on-line consent and privacy in social networks), SMART and RESPECT (which cover smart and on-line surveillance, etc.) MAPPING’s goal is to create an all-round and “joined-up” understanding of the many and varied economic, social, legal and ethical aspects of the recent developments on the Internet, and their consequences for the individual and society at large. MAPPING would specifically investigate and debate the existing innovation policies, business models and legal framework related to the implementation of the Digital Agenda for Europe and the changes needed to set up an improved governance structure for the EU innovation ecosystem. The key to MAPPING’s success would be its planned mobilisation of a wide spectrum of ICT-related stakeholders and social actors from both EU Member States and associated countries, including academics, law and policy makers, ISPs, international and EU Internet governance bodies, NGOs and civil society organisations. The project would provide these actors with a forum for informed discussion of issues related to the digital transition, such as problems of personal data and IPR protection online, business models and e-government applications based on the use of personal data, economic exploitation of IPRs and open innovation. MAPPING would then move to create an Action Plan and put forward workable policy guidelines based on a multidisciplinary perspective on the latest and foreseeable developments in ICTs taking into account conflicting interests, perceptions and practices of different societal actors that shape the EU’s technological future.  MAPPING would thus significantly contribute to creating an enabling framework for completing the digital transition an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'The Impact of Neural plasticity on the crossed facilitation of motor pathways'.

assistant: **Concept**

Each year approximately 1 million people living in the countries of the EU suffer a stroke. In Western Europe stroke is the third most common cause of death, whereas in the EU Enlargement countries it is the most frequent cause.Mortality data however tend to underestimate the true burden of stroke to European society, as the major outcome is disability rather than death. Stroke accounts for 23% of all chronic disability in Europe. The search for effective strategies of rehabilitation has therefore become m ore pressing.The ease with which we perform tasks in which the two hands execute quite different actions belies the fact that there is a strong tendency for movements of the limbs to be drawn together. These findings are not simply of academic interest. The systematic nature of these interactions has given rise to the expectation that for stroke survivors, functional improvements in the control of a paretic limb may be realised when movements are performed in a bimanual context.Recent research has also suggested that the adult brain retains an extensive facility to undergo adaptive change or reorganisation. This capacity is referred to as neural plasticity. Among health care professionals and scientists alike, it is now recognised that plasticity is a critical precursor for the recovery of motor function following brain injury.It is also increasingly apparent that in order to capitalise fully upon neural plasticity, it is necessary to utilise movement-based therapeutic interventions in order to drive recovery of function. The aim of the proposed project is to increase our understanding of interventions that enhance plasticity and alter the sensitivity of the cortex to the additional neural inputs generated by movement of the opposite limb.This strategic basic research
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Photoresponsive Multi-Addressable Smart Materials and Mechanical Synthesis by Molecular Machines', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

In this proposal a research program is envisioned to make a true leap in the creation of light-responsive intelligent matter. It targets the current frontiers and limits of photoswitching, molecular machines, chemical synthesis, and precision engineering of multi-responsive materials and will have profound impacts in - and beyond these fields. It encompasses the creation of novel visible-light responsive photoswitches with general applicability across the natural sciences and the elucidation of a plethora of hitherto unknown photoreactions in the first stage. Exploring the class of indigoid chromophores simple and compact molecular units will be developed offering hitherto unachievable control over molecular states and motions within a single such entity. Building on these findings molecular precision engineering of functional multi-state and multi-responsive materials will be explored in the second stage. Applications for molecular information processing, advanced surface patterning, or programmable adaptive behaviour will be used to demonstrate the unique advantages of this molecular approach for creation of next-level smart materials.  In the last two parts of the proposal unprecedented molecular machines and a completely new type of chemical synthesis will be developed, which is termed “mechanical molecular construction”. The latter is exploiting the unique properties of molecular motors and can be regarded as first step into the uncharted territory of “molecular weaving”. This will open up an entire realm of untapped chemical and material structures for future explorations. Knowledge and methods created in these projects will be of utmost importance for any scientist – academic or industrial – concerned with applying light as central means for manipulating matter a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'LOW COST POWER AND FLOW CONTROL SYSTEM FOR REMOTE SUBSET FIELDS' (MURCS).

assistant: **Innovation**

To demonstrate a low cost system for the remote control of subsea wellheads which eliminates the need for electro-hydraulic umbilicals. A Minimum Umbilical Remote Control System (MURCS) provides all the capabilities of current subsea control systems. This system is not limited by water depth or wellhead offset from the production platform. The subsea production (or injection) system is linked to surface with a simple fibre optic umbilical and chemical injection line which is attached to the production flowline. A consortium of European suppliers have combined their equipment developments to create a remote power supply and seawater hydraulic system which form the key elements of this low cost system.L%The subsea skid demonstrated it's operation underwater and proved reliable. The separator has demonstrated extremely good sand separation performance and has shown that it can protect the expander from sand carried by the gas; the expander suffered very rapid deterioration of performance due to sand erosion. The extent of the damage has been quantified and the expander has been refurbished in preparation for the system tests.This project demonstrates all the subsystems required to generate and control electrical and seawater hydraulic power. The major subsystems include control, power supply and hydraulically actuated components. Interface engineering, of the concepts which have been previously developed or tested as discrete components, is included to ensure the assembled system is coherent and complete. Representative components will be fabricated and assembled into a working remote control system.One of the major enabling technologies being demonstrated is a robust, high capacity, subsea power supply driven by produced fluids. A 15 kW gas expander owned by Mobil North S
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Enhancing Earth Observation capabilities of the Eratosthenes Centre of Excellence on Disaster Risk Reduction through Artificial Intelligence'.

assistant: **Innovation**

Artificial Intelligence (AI) has a major impact on many sectors and its influence is predicted to expand rapidly in the coming years. One area where there is considerable untapped potential for AI is in the field of Earth Observation, where it can be used to manage large datasets, find new insights in data and generate new products and services. AI is one of the missing core areas that need to be integrated in the EO capabilities of the ERATOSTHENES Centre of Excellence (ECoE). AI-OBSERVER project aims to significantly strengthen and stimulate the scientific excellence and innovation capacity, as well as the research management and administrative skills of the ECoE, through several capacity building activities on AI for EO applications in the Disaster Risk Reduction thematic area, upgrading and modernising its existing department of Resilient Society, as well as its research management and administration departments, and assisting the ECoE to reach its long-term objective of raised excellence on AI for EO on environmental hazards. A close and strategic partnership between the ECoE from Cyprus (Widening country) and two internationally top-class leading research institutions, the German Research Centre for Artificial Intelligence (DFKI) from Germany and the University of Rome Tor Vergata (UNITOV) from Italy, will be achieved, leading to a research exploratory project on the application of AI on EO for multi-hazard monitoring and assessment in Cyprus. Moreover, CELLOCK Ltd. (CLK), the project’s industrial partner, will lead the commercialisation, exploitation and product development aspects of AI-OBSERVER and its exploratory project outputs. All outputs will be disseminated and communicated to stakeholders, the research community, and the public, assisting the ECoE to acc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Instrumented 3D-Printed Miniature Muscles for Cardiotoxicity Screens of Cancer Therapies' under Horizon 2020.

assistant: **Concept**

Rationale: Cardiotoxicity side effects are a recurrent problem for cancer therapies, fatally illustrated by the death of numerous patients treated with anthracycline chemotherapeutics. More recently, cardiac complications have also been found for antibody-based and immunotherapy treatments. Microphysiological systems and organs-on-chips may provide part of the long-term solution to these issues, by introducing improved means for studying human tissue in vitro. Main objective: The overarching objective of IN-3D-CAN is to establish instrumented in vitro 3D models of human cardiac muscle for high-throughput cardiotoxicity screening of cancer drugs and therapies. Methodology: In a recent first-author paper in Nature Materials, we reported the first entirely 3D-printed organ-on-chip with integrated sensors: A heart-on-a-chip with strain sensors for tracking engineered 2D cardiac thin films. In this proposal, I significantly expand on this 3D printing methodology, focusing on thicker 3D tissue models that better recapitulate native cardiac muscle. I will leverage the insights of the supervisor to perform toxicity screening of a range of cancer therapies. Outcomes: The proposal will establish unique tools for long-term and high-throughput studies of drug toxicity on human cardiac muscle in vitro. It will further provide unique insights into the cardiotoxicity of several cancer therapies on human cardiac muscle. Finally, the techniques for 3D printing will be widely applicable for biomedical micro-devices. Career: I am applying for an MSCA-IF-EF-RI, to reintegrate to DTU(DK), after more than 4 years abroad as Postdoc at Harvard Uni. (US) The fellowship will serve as year 1 and 2 of a 4-year assistant professorship. The host DTU Nanotech has committed to provide funding for year