RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Cluster Management beyond High Performance Computing' under Horizon 2020.

assistant: **Concept**

This project concerns the further development and scaling up of Bright Cluster Manager beyond High Performance Computing (Bright Beyond HPC). It shall gain advanced functionalities in the areas of Big Data and Cloud computing. The enhancements shall enable Bright Computing to expand their market position significantly and the technology enables the market to benefit, in an ease-of-use manner, of Cluster Management. Bright Computing is a Dutch, venture-backed tech company, and is a partner of the European Technology Platform For High Performance Computing (ETP4HPC, see also www.etp4hpc.eu), and has already reached a mature position in the High Performance Computing Cluster Management market. This project ensures further deployment into the EU market and is the necessary step for scaling up of the innovation activities in order to take High Performance Computing to the next level.The objective of this project is to solve the Cluster Management problem in the High Performance Computing, Big Data/Hadoop and OpenStack Cloud Computing markets by developing and bringing Bright Beyond HPC to market readiness.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Evolutionary origin of cell adhesion: the basis of multicellularity in the choanoflagellate Choanoeca flexa' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

How animal multicellularity evolved from unicellular ancestors remains an open evolutionary question. One key pre-requisite for the evolution of animal multicellularity was the evolution of cell adhesion. However, little is known about how cell adhesion evolved in the animal stem. In the last decades, considerable advances to reconstruct early animal evolution have come from investigations of the closest living unicellular relatives of animals, notably the choanoflagellates. These microeukaryotes have become powerful models to address the evolution of animals, for several reasons: (1) they are the sister group to all animals; (2) their genomes encode homologs of genes that can inform about animal origins, including an animal-like “cell-adhesion toolkit”; (3) they can temporarily adhere to each other and form multicellular colonies; and (4) they are amenable to functional genetics. Therefore, studies on choanoflagellate molecular and cell biology can inform the mechanisms of the emergence of multicellularity in animals. Here, I will investigate the cell adhesion mechanisms governing multicellularity in the recently discovered choanoflagellate Choanoeca flexa. C. flexa has direct cell-cell adhesion and aggregative multicellularity (unique in choanoflagellates) and also undergoes light-controlled collective contractility of colonies (unique in unicellular relatives of animals), making it a powerful model to study the emergence of collective behaviors. I will perform a systematic characterization of the environmental and endogenous factors regulating cell adhesion during colony formation in C. flexa using a combination of genetic engineering, biochemistry, proteomics, molecular and cell biology approaches, and functional genomics. The data generated here will contribute to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'EuroNanoForum 2015' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

This proposal is about organising the 2015 EuroNanoForum conference (ENF 2015) in Riga as part of the Latvian presidency of the European Union. The conference will focus in nano and materials technologies, strengthening European competitiveness and supporting the renewal and recovery from the economic crisis. The event will review the 2015 status of European nanotechnology, including the latest progress in nanoscience, innovations and business. The most relevant application fields and enabling technologies will be reviewed. In addition, the different aspects impacting European competitiveness will be covered, including smart specialisation, public-private partnerships, local support and Horizon 2020. In addition, the framework conditions like education, standardisation, regulations, IPR and safety issues, as well as issues related to entrepreneur- and industry-friendly decision making are included. The conference will also build on agendas of the previous conferences such as commercialisation and start-ups. The conference will be organised on 10-12.6.2015. The conference will feature plenary sessions, presentations, workshops, poster sessions and a brokerage event. In addition, specific evening program for the speakers and delegates will be organised in order to give opportunities for networking during the conference days. The NanoTechEurope exhibition will complement the event as separate but parallel activity, showcasing various organisations and activities related to nanotechnology. The event will include also the best project, the best poster and the best exhibition stand competitions.  The European nanotechnology community, including the technology platforms and industrial associations, will be integrated in planning the content. A range of communications activitie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Healthy Working environments for all Ages: An evidence-driven framework' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

The WAge project will develop and validate the first comprehensive framework for assessing and understanding the roles and interactions between physical and psychosocial risk factors across age groups through robust modelling and policy-relevant evidence gathering. Through the proposed framework, the project will pave the way for designing, implementing and validating effective multi-level intervention strategies and policy changes for workers of all ages at the individual and organizational level. The project focuses on a question that has high societal relevance and is timely because the proportion of employees under adverse physical and psychosocial work environments is likely to increase as organisations, businesses, and workers have to adapt to post-pandemic working environments in an ageing Europe.WAge is proposing a concept that is addressing the factors related to the health and overall wellbeing of workers across age groups. One of the main aims of the proposed action is the generation of integral, policy-relevant evidence that are vital for the improvement and update of occupational health but also for this HORIZON Europe call. In WAge, the gathering and utilization of evidence within decision-making spaces will be based on representation and accountability of policymaking, bringing multiple perspectives and knowledge through democratic participation into decision-making processes across the project, from data collection, and management, to analysis, and implementation.


**Keywords:** policy-relevant evidence, participatory research, work demands, intervention, data sovereignty
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Labour Market Institutions, European Unemployment and Economic Performance in a Dynamic Perspective' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

Research objectives and content:The expansion-contraction impulses on the economical system can produce different employment-hours paths, depending on the adjustment costs structure faced by firms. These costs are determined by the institutional configuration of the labour markets. The aim of the research project is the identification and quantification of the impact of the different institutional variables on the employment and hours dynamics in each phase of the cycle. This can explain, for example, which are the features of continental Europe labour markets that are responsible for the reduction of the employment rise during an expansion phase, especially if compared to the performances of the Anglo-Saxon economies. Besides the analysis will show which institutional labour market configuration is likely to increase the speed of adjustment of employment to output, during the same expansion reducing the social loss associated to the recessive phase of the cycle. The approach followed will be Panel Data Analysis using aggregate as well as sectoral OECD data. To measure the impact of labour market regulations on the employment-hours dynamics in the economy considered as a whole as well as in different sectorsTraining content (objective, benefit and expected impact)It is my objective to obtain the academic grade Doctor of Philosophy of the University of Oxford. Continuing to benefit the excellent research and training environment of the university as I experimented it during my MPhil course. In addition, I will have the opportunity to work with Prof. Steven Nickell one of the major experts on the subject reinforcing my knowledge of empirical economics techniques and Labour Economics. This research itself is the first attempt to study the dynamical relations of labour mark
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Forecasting and understanding the seIsmic cycle through b-value' in the context of a Horizon Europe call.

assistant: **Objectives**

Seismology is a branch of science with many open questions, and predicting earthquakes is still a utopia. We know earthquakes interact with each other by changing the state of stress in their surroundings. Strong earthquakes are, for example, followed by countless smaller events, a posteriori called aftershocks, whose number decays with time. We have shown that aftershock sequences are systematically associated with changes in the average earthquake size distribution,  an increase in the so-called b-value, unless a second large mainshock is still coming, in which case the b-value decreases. This exciting finding allows the use of the b-value for real-time discrimination between foreshocks and aftershocks, answering the most asked question following a moderate/big quake: Was this the mainshock or a bigger event has yet to come? The observation also aligns with the concept that the b-value can be used as an indirect stress meter in the earth’s crust. Building on these findings, I propose here now to develop and test a general model of the evolution of the b-value through the seismic cycle, building on the following hypothesis: 1) a stable background or gradual decreasing b-value during inter-seismic times, 2) occasionally a pre-mainshock decrease, 3) an increase after the mainshock and 4) recovery to the background value. According to my hypothesis, monitoring b-values in real-time allows us to understand and monitor for the first where a fault is in the seismic cycle. This would represent a major breakthrough in Earth science, with profound implications for understanding earthquake processes, seismic hazard assessment and risk mitigation. To achieve this ambitious goal, FARIA comprises a set of closely coordinated activities in data analytics, computational modeling, lab
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Radiation specific DNA non-double strand break lesions: repair mechanisms and biological effects' to be submitted under Fifth Framework.

assistant: **Abstract**

Ionising radiation induces a plethora of DNA non-double strand break lesions such as oxidised bases, a basic sites and single strand breaks. Strong evidence exists that ionising radiation induces, besides isolated DNA lesions; a unique form o f DNA damage termed clustered damage consisting of closely spaced lesions on opposite DNA strands. There is also evidence that repair of lesions within clustered damage sites is compromised compared with the effective repair of isolated lesions.We will investigate the following aspects of radiation-induced single and clustered DNA damage: (i) frequency and nature of the damage, (ii) mechanisms of repair, (iii) interference with transcription, replication and chromatin dynamics and (iv) biological consequences (stress responses, mutations, lethality). To achieve these goals we will exploit a variety of new technologies and utilise different organisms with defined mutations in damage response genes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'ONYX_GRAPHENE AND THIN FILM INSPECTOR' (ONYX).

assistant: **Concept**

1. Currently indium-tin-oxide (ITO) is the standard material for the mobile device displays industry, with an annual production over 25.000 m2.2. The industry, together with Research & Science institutions, is looking for substitute materials for ITO, in the search for better performance, flexible displays and to satisfy the market growth of the coming years in mobile devices.3. Graphene and other thin film materials are the most promising candidates to revolutionize the display industry.4. The lack of agility of current inspection and characterization methods makes difficult the establishment of efficient quality control processes, hindering the production of thin films on a large scale and in a cost effective way.5. In order to speed-up the development of those new materials, a real-time and full fabricated area characterization system is needed.6. In this framework, das-nano has developed an innovative characterization tool (ONYX Graphene & Thin Film Quality Inspector) which will allow screen manufacturers to speed up the development process of the new materials, bringing graphene and thin films production to industrial readiness, to unlock the next era of consumer electronic technology.Das-Nano’s Onyx provides an increment of up to 100x in the speed of the characterization process during the research and development stage thus allowing a huge reduction in the time to market. Onyx will also be ready for the on-line manufacturing process control in the display industry when those materials will reach the industrial stage.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Nudix hydrolases in Cancer Therapy', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Cancer is the activation of dysfunctional pathways leading to abnormal behaviour of cells. A hallmark of cancer is genomic instability, triggered by a range of DNA lesions such as 8-oxo-G, caused by reactive oxygen species (ROS). ROS are generated by the cell’s metabolism and are crucial for its homeostasis. However, excessive ROS levels can induce DNA lesions resulting in increased mutations, fuelling genetic instability favouring carcinogenesis. Free dNTP are more easily damaged by ROS and are cleared from the nucleotide pool by dNTP pyrophosphatases and the nucleoside diphosphate linked moiety X family (Nudix) hydrolases, consisting of 22 members. These highly specialized proteins hydrolyse oxidized lesions such as 8-oxodGTP present in the nucleotide pool, thus preventing the incorporation of oxidized nucleotides into the RNA or the DNA. Cancer cells sustain abnormally high levels of ROS generated by deregulated metabolism and protein translation. Preliminary data from the host laboratory suggest that the Nudix hydrolase MTH1 is overexpressed in cancer and that cancer cells require its catalytic activity for survival. This is interesting, as normal cells do not rely on MTH1 for survival. Small molecule inhibitors from the host laboratory targeting MTH1, effectively kill transforming cells but not the parental immortalized cells. Thus, I hypothesize that the Nudix hydrolases may play important roles in cancer, and that insight into this pathway can be exploited to design novel anti-cancer strategies. The functions of a large portion of the 22 Nudix hydrolases are unknown. The objective of this project is to determine the biological and biochemical roles of all the Nudix hydrolases in cancer, including resistance and relapse, and thereby identify potential novel target
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Soot formation in diffusion flames' (1994-1998).

assistant: **Innovation**

I have previously studied soot formation in a counterflow diffusion flame under the direction of Professor A Linan as supervisor. In this particular case, we used the Burke-Schumann analysis and a simplified kinetic model for both combustion and soot formation to characterise the influence of the maximum flame temperature and the strain rate. In the new project we will address several categories of flame and we will focus our interest on the soot production. First we will choose another kinetic model but we will intend to extend the study with different models. We will take into account radiation and thermophoresis effects that occur when soot appears and change the soot production. The main goal of this project is to obtain simplified descriptions in the analysis of soot production. In this scheme, we will use asymptotic technique which theoretical results will be confronted to numerical results. The study will at last consider the industrial aspects - burnace, fuel engine, jet engine - and also environment.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Asset Centric Adaptive Protection' under Horizon 2020.

assistant: **Concept**

The proliferation of mobile and ubiquitous computing technology is radically changing the ways in which we live our lives: from interacting with friends & family, to how we produce & consume services and engage in business. However, this pervasiveness of technologies, and their increasingly seamless integration and inter-operation, are blurring the boundaries  between systems. This poses significant challenges for security engineers who aim to design systems that monitor and control the movement of digital or physical assets across those boundaries.My ERC Advanced Grant on Adaptive Security and Privacy (ASAP) is investigating ways in which security controls can change in response to changes in the context of operation of systems. However, since the monitoring of such elusive and changing boundaries is difficult, we have developed an adaptive security approach that monitors valuable assets that are managed by a system, and changes the means and extent by which those assets are protected in response to changes in assets and their values. This could radically change the way security is designed and implemented in a range of applications because it allows for a choice of appropriate protection, depending on particular requirements.In ASAP, we developed the modelling and computational capabilities  of our approach, including some prototype tool fragments that demonstrate the approach in our lab. However, interest from our industrial collaborators, evidenced by direct funding of follow-on research, and the demonstration of our prototypes to senior management and potential customers, has motivated us to pursue a proof of concept (PoC) assessment of our work in a more systematic and targeted way. To this end, this ERC PoC will:1) Develop a robust prototype demonstrator, instant