RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Renal stem cells: possible role in kidney pathologies and as new theraputic tools' (RESCARF) targeting Seventh Framework.

assistant: **Abstract**

Chronic Kidney Disease (CKD) affects 11% of the adult population and is considered by the WHO as one of the health emergencies of the 21st century. Although cell therapy might be beneficial for CKD, human stem cells that might be used to improve kidney function were so far unknown. Recently, we demonstrated the existence of resident stem cells in the urinary pole of the Bowman’s capsule of adult human kidney and therefore named as adult parietal epithelial multipotent progenitors (APEMP). Injection of APEMP in SCID mice affected by acute renal failure, induced regeneration of tubular structures and reduced morphological and functional kidney damage. More recently, we found that APEMP are highly represented in embryonic kidneys and constitute the common progenitor of tubular cells and podocytes. The first aim of this project is to assess the regenerative properties of APEMP in in vivo models of glomerular injury and their potential use as a novel therapeutic tool to prevent the deterioration of kidney function in chronic renal failure. Second, we will try to identify the mechanisms that regulate the growth, survival, differentiation, and migration of APEMP, which is critical to set up cell therapies of renal injury which should be effective and safe. To this end, the role of different molecular pathways such as Sonic hedgehog, Wnt/beta-catenin, Notch, TGF-beta/BMP and of CXCR4, CXCR7 or CXCR3-B chemokine receptors in the regenerative activity of APEMP will be investigated. Third, to assess whether APEMP directly contribute to kidney regeneration after glomerular or tubular damage, transgenic animals in which APEMP are genetically tagged will be generated. Fourth, by using transgenic animals we will try to understand if an alteration of APEMP growth and/or differentiation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Pollution from aircraft emissions In the North Atlantic flight corridor' (POLINAT-2).

assistant: **Concept**

To determine by measurements and analysis the relative contribution from air traffic exhaust emissions to the composition of the lower stratosphere and upper troposphere at altitudes between 9 and 13 km within and near the flight corridor over the North Atlantic. To assess the effects of air traffic emissions in that region in relation to clean back-ground concentrations and pollutant concentrations from various sources and to analyze their importance for changes in ozone, oxidising capacity, aerosols and clouds.The work programme includes the following tasks:  Task 1: Performance of in situ measurements within and near to the flight corridor extending over the whole  corridor scale, with focus on winter weather conditions.  - Improve and complete instruments to be used onboard the Falcon. - Performance of a Falcon measurement campaign in winter early 1997 including weather forecasts for the  campaign planning.  - Measurements with a B747 of NO, NO2, O3 and H2O along the North Atlantic route and coordination with  MOZAIC measurements.  - Set-up of data bank  Task 2: Analysis and interpretation of the previous and the additional measurements in correlation with the  actual emissions, meteorology and background air chemistry conditions during the measurement periods.  - Refinement of models  - Analysis of the horizontal and vertical trace gas distributions - Quantification of the relative contributions from surface emissions relative to air traffic emissions  - Determination of the frequency and area sizes of regions with ice supersaturation  - Analysis of interaction between multiple plumes  - Analysis of ozone chemistry, mainly in upper troposphere and also in lower stratosphere for measured  situations.  The platforms and tools, which will be used in the project, are:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Archaeological Automatic Interpretation and Documentation of cEramics' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The objectives of ArchAIDE are to support the classification and interpretation work of archaeologists with innovative computer-based tools, able to provide the user with features for the semi-automatic description and matching of potsherds over the huge existing ceramic catalogues. Pottery classification is of fundamental importance for the comprehension and dating of the archaeological contexts, and for understanding production, trade flows and social interactions, but it requires complex skills and it is a very time consuming activity, both for researchers and professionals. This tool would revolutionise archaeologists habits, behaviours and expectations, would meet real user needs and generate economic benefits, reducing time and costs, would create societal benefits from cultural heritage, improving access, re-use and exploitation of the digital cultural heritage in a sustainable way. These objectives will be achieved through the development of:-an as-automatic-as-possible procedure to transform the paper catalogues in a digital description, to be used as a data pool for search and retrieval process;-a tool (mainly designed for mobile devices) that will support archaeologists in recognising and classifying potsherds during excavation and post-excavation analysis, through an easy-to-use interface and efficient algorithms for characterization, search and retrieval of the visual/geometrical correspondences; -an automatic procedure to derive a complete potsherd’s identity card by transforming the data collected into a formatted electronic document, printable or visual; -a web-based real-time data visualization to improve access to archaeological heritage and generate new understanding; -an open archive to allow the archival and re-use of archaeological data, transformi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Designing and improving health and food related production processes using filamentous fungal cell factories'.

assistant: **Objectives**

The main goal of the Eurofung project is to design and to improve health and food related fungal production processes. Three different product categories of industrial interest are investigated1) Heterologous proteins of medical importance (cytokines, antibodies and allergens)2) Enzymes used in food and feed applications3) Novel non ribosomat peptide antibiotics. These processes will be improved by solving specific problems associated with each of them and generic problems associated with fungal behaviour in fermenters. The project requires a multidisciplinary approach in which solid process engineering and advanced mathematical modelling are complemented by state of the art biochemistry and molecular genetics to construct fungal strains of high productivity.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Exploiting the full integration potential of fluctuating renewable energies in power grid operation by new predictive technologies' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Over the past years, a lot of (political) initiatives led to rising numbers of decentralized renewable energy generators like wind parks and solar plants, even on rooftops of private households. Although this tendency is very positive concerning the targeted energy transition and for reaching the EU’s valuable 2030 climate and energy goals, the thousands of different decentralized power supply units connected in different parts of the grid, at different voltage levels and under different grid code standards challenge grid operators. The volatility of renewable energy generation (caused by weather conditions) and the need to balance power generation and demand within grids head to an oxymoron: although wind blows and sun shines, grid operators have to reactively curtail these plants from the grid to guarantee grid safety. Current control room systems are not made for a proactive and exact management and control of single assets  – limiting the share of renewable energies in our power mix to a lower level than it’s possible. To fully exploit the potential of clean and green energy by 100%, energy & meteo systems developed FuturePowerFlow, an algorithm-based, modular system which uses weather forecasts, locations of renewable energy plants, data on grid infrastructure, historic demand data and even operating status of plants (iced, under maintenance, etc) to predict power flows in the grid based on generation and consumption for the next 48h in very high time-resolution. Instead of reacting just demand driven, FuturePowerFlow enables grid operators for the first time ever to proactively plan and manage the integration of decentralized renewable assets into their grid and execute precise actions within one system.FuturePowerFlow targets on a EUR 2.6bn energy market and is t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Antibiotic resistance of functional microbes in wastewater treatment systems'.

assistant: **Objectives**

The Urban Wastewater Treatment Directive (UWWTD) adopted by the European Union recognizes biological treatment processes as sustainable and cost-effective solutions for pollutant removal from wastewater, thereby mitigating ecological damage. However, there is a growing awareness that the biological units within wastewater treatment plants (WWTPs) serve as hotspots for antimicrobial resistance (AMR), which presents significant health risks. Preventing the spread of antibiotic resistance genes (ARGs) while maintaining the wastewater treatment efficiency is a great challenge for WWTPs. ARFMW project focuses on functional microbes in WWTPs, which are not only pivotal to pollutant degradation but also potential reservoirs for ARGs. Our objective is to employ a multidisciplinary approach that integrates ecological and engineering principles with cutting-edge multi-omics analyses and molecular techniques, to elucidate the AMR characteristics of functional microbes and their impact on wastewater treatment. Hosted by the Water Technology group, Aarhus University, under the supervision of Prof. Barth F. Smets, I will expand my core research skills in microbial technology and water engineering to operate lab-scale bioreactor for investigating the relationship between the spread of ARGs in functional microbes and the performance of wastewater treatment. During the secondment at University of Helsinki, Finland, under the guidance of Prof. Marko Virta, I will gain complementary skills in advanced molecular techniques (epicPCR) to identify comprehensive host information of specific ARGs. Additionally, this project will augment my transferable skills such as project management, communication and leadership, thereby propelling me to become a mature researcher. ARFMW will also engage wit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'SEAmless Content Delivery' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

In the forthcoming age, where everyone may be content producer, mediator and consumer, SEA aims to offer a new experience of personalised, seamless content delivery, maintaining the integrity and wherever applicable, enriching the perceived QoS (PQoS) of the media across the whole distribution chain. SEA is a project focused on seamless, personalised, trusted and PQoS-optimised multimedia content delivery, across broadband networks, varying from broadcasting to P2P topologies. <br/>SEA motivation is to implement a context-aware networking delivery platform, by focusing on four key principles:<br/>- Multi-layered/-viewed content coding, considering the evolving H.264 SVC/MVC and their emerging successors, as the major foreseen delivery technologies over heterogeneous networks/terminals and large audiences. <br/>- Multi-source/-network content streaming offering on-the fly content adaptation, increased scalability and enriched PQoS by dynamically combining content layers or representations of the same resource, transmitted from multiple sources and/or received over multiple networks. <br/>- Cross-network/-layer optimisation. The network/terminal heterogeneity, also engaging P2P overlays and serving different quality and views will require cross-layer optimization, traffic adaptation and optimal use of the available network/terminal resources.<br/>- Content Protection. A hybrid solution for personalised content protection by means of a combination of streaming encryption, content protection and rights management for new media, covering not only the legacy content creation chain, but also the private multimedia content. <br/>SEA will test/validate the developed technologies over three interconnected tedbeds: a) a real-time emulated lab, b) a world-wide extended P2P testbed
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Researchers' night 2010' under Seventh Framework.

assistant: **Concept**

The main aim of the project is to mobilize more than 200 researchers and bring them closer to the PUBLIC AT LARGE in order to enhance researchers’ public recognition; the main aim of the project is to make an opportunity for people, in particular younger people, to meet researchers within the context of festive activities and to highlight the importance of a research career. We aim to reinforce the links between research institutions and citizens, bring research closer to the public and public closer to research in order to find better communication and also collaboration; to present various sciences and researchers from various scientific fields; to motivate younger people, graduating a high school, to choose researchers’ life or be more involved into science. Also, we intend to reinforce the link between researchers themselves among various disciplines.To reach this aim, partners from various science institutions by implementing more than 50 diverse activities ( 1) Opened laboratories; 2) Lectures, discussions; 3) Real life observations and experiments; 4) Teleconferences; 5) Humoristic play about researchers’ life and work; 6) Various contest, movie watching, broadcast online watching, exhibitions.) in main cities of Lithuania and 10 rural areas. All events would be broadcasting online during Researchers’ night.The goal of the project is to reach around 300 000 (10% of the whole population) Lithuanian citizens by awareness company and attract 7 000 people which participate in real life activities and visit various sites of activities, and 10000 people who will watch broadcasts from the main sites.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Advanced ingestibles for probing the nexus between gastrointestinal functions and physical/mental well-being in animals and humans' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Expanding on the eHONESTY ERC project about the link between body and moral decisions, the DeepDive PoC proposal aims to explore the neglected role of deep-body signals in modulating physical/mental health in humans and animals through the radically new approach of using ingestibles for mapping gastrointestinal (GI) physiology. Crucially, although the market of ingestible devices is burgeoning, none of the existing products has the features needed for probing the link between GI dys/functions and physical/mental well-being in humans and animals. To fill this outstanding gap, the DeepDive project aims to develop and test a class of ingestibles that can capture from different tracts of the GI system (e.g., stomach, small/large intestine), physiological signals like endoluminal pH, pressure, and temperature with unprecedented accuracy and precision; and, remarkably, add causation to correlation by recording the GI neurons' activity before and after their electrical perturbation. The inert capsules will be produced by: i) assembling specific components created using 3D printing and ii) integrating a number of microscopic components ranging from solid state pH, temperature, and pressure sensors to A/DD/A Microconverter and RF Radio 2.4 GHz, in a sub-centimetric space. GI functions at rest and in conditions of social stress will be tested in piglets using the new ingestible and in humans using commercial pills. All the steps towards patenting and obtaining permission for use in humans of the novel ingestible will be taken, and existing contacts with industrial partners and biomedical devices approval offices will be strengthened. Given the link of gastroenterology with physical/mental dys/functions and human/animal well-being, the project will have significant benefits at neu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'MANUFACTURING OPTIMIZATION OF A PLENUM WITH GFRP CYANATE ESTER-BASED PREPREG'.

assistant: **Innovation**

Cyanate ester resins offer significant advantages as composite matrices because of their high thermal stability, their improved toughness, low outgassing, low moisture uptake and radiation resistance due to their low dielectric constant. Towards the direction of incorporating these materials in the aerospace industry, a new glass/cyanate ester material system was characterized for use in the plenum of the air cooling unit of aircrafts. However, the first trials with this new prepreg to manufacture real parts (plenum housing) in an autoclave, highlighted some heterogeneity issues in the reliability and reproducibility of the manufacturing process.PLENOPTIMUM project aims to address the reasons that lead to the aforementioned heterogeneities and through a novel Design of Experiments approach identify a number of possible influential factors that affect the manufacturing process (in autoclave and out-of-autoclave) and potentially cause deviations and heterogeneities. For the first time, factors additional to temperature profile and pressure shall be examined according to their effect on the final quality of the composite materials and the actual plenum. Process modeling as well as online curing monitoring technologies will assist the optimization task and the quest of the optimum curing cycle.Manufacturing trials for plenum manufacturing in an autoclave as well as out-of-autoclave process will take place in the final part of the project taking into account the results of a test campaign specially designed to highlight the effect each one of the identified influential factors has. Guidelines and recommendations to the topic manager and manufacturer that ensure and optimize the manufacturing process are the final outcome.Both participants that form PLENOPTIMUM consortium hav
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'ThE ATMOSPHERIC PRESSURE CHEMICAL VAPOUR DEPOSITION OF ALUMINIA COATINGS ONTO METAL CUTTING AND FORMING TOOLS MADE FROM TOOL STEELS' (1994-1998).

assistant: **Innovation**

Alumina coatings are to be deposited on to tool steel cutting and forming tools in an attempt to obtain improvements in performance which are substantially greater than those currently afforded by titanium nitride coatings. Deposition will be carried out at atmospheric pressure using aluminium chloride precursor obtained by the evaporation of powder rather than by reaction between hydrogen chloride and aluminium. The feasibility of this deposition route has already been established in the laboratory; as also has the necessity for a precoating on the tool steels. Following completion of this laboratory-scale research, a pilot-scale CVD reactor will be constructed, and the deposition conditions for the precoating and alumina coating established in the laboratory will be scaled-up and transferred to this reactor. A range of tool steel cutting and forming tools will then be selected and these tools coated with alumina in the pilot-scale reactor. Both conventionally produced and atmosphere-sintered tool steels are to be employed in an attempt to optimise coating/substrate combinations for different applications. Comparative testing of the alumina coated tools against titanium nitride coated tools will then be performed, both in the laboratory and also under industrial conditions.