RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Investigting the effects of psychedelics on Lateral Habenula-Dorsal Raphe Nuclei circuitry in a Chronic Unpredictable Stress model of depression' (PsyHab).

assistant: **Concept**

The lateral habenula (LHb) and dorsal raphe nuclei (DRN) are key structures in the brain involved in mood regulation, reward processing, and aversive signaling. The LHb is a small, yet critical brain region that acts as a major negative regulator of midbrain dopamine systems. It plays a significant role in processing aversive stimuli and encoding negative reward prediction errors, which are crucial for adaptive behaviors and decision-making processes. The DRN, on the other hand, is the primary source of serotonergic projections to various brain regions and is a key structure involved in mood regulation and the pathophysiology of depression. Understanding the precise anatomical and functional connections between the LHb and DRN is essential, as disruptions in the LHb-DRN circuitry are believed to contribute to various neuropsychiatric disorders, including depression and anxiety. Psychedelics have garnered significant interest in both clinical and neuropharmacological research due to their profound effects on perception, cognition, and mood. Their influence on the activity of the LHb is not yet fully understood, but we hypothesize that it could potentially reduce the hyperactivity of the LHb by altering its neural inputs or by modulating the overall excitability of the neurons within the LHb.  The proposed research is aimed at examining how psychedelics affect LHb-DRN circuitry in the chronic mild stress model of depression. We will combine viral tracing, in situ sequencing, fiber photometry, chemogenetics, and unsupervised learning in order to evaluate the effects that psychedelics exert on projections from DRN to LHb, and how those translate into changes in animal behavior. The proposed research will contribute to a better understanding of the antidepressant potential o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'A Voice Enabled Residential Automation & Networking platform' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

HomeTalk creates a truly intelligent user-friendly residential environment, connected to a broadband network, equipped with advanced domestic appliances, controlled via powerline by a multifunctional residential gateway/controller andcapable of communicating with the residents via natural voice interface (recognition and synthesis). A vertical Service Creation framework will make the most of the available media and networks convergence to nurture advanced servicesfor the Residents. HomeTalk develops an innovative, distributed Communication & Control platform for the Future Home, creates awareness and contributes to Standards and Special Interest Groups related to Service Convergence, Broadband Access and Intelligent Home Networking. Through an Open Source initiative, HomeTalk will integrate with OSGI, VoiceXML and Home Automation development efforts in an open manner, to catalyze international adoption.OBJECTIVESHomeTalk creates a truly intelligent user-friendly residential environment, connected to a broadband network, equipped with advanced domestic appliances, controlled via powerline by a multifunctional residential gateway/controller and capable of communicating with the residents via natural voice interface(recognition and synthesis). A vertical Service Creation architectural framework will make many available media and networks convergence to nurture advanced services for the Residents. HomeTalk develops an innovative, distributed Communication & Control platform for the future home, creates awareness and contributes to Standards and Special Interest Groups related to Service Convergence and Interoperability, Broadband Access and Home Networking. Through an Open Source development initiative, it will integrate results with OSGI, VoiceXML and Powerline efforts to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Reducing the burden of non-insulin dependent diabetes mellitus by health education in a primary care setting' under Fourth Framework.

assistant: **Concept**

Objectives: - to asses the efficacy of a special diet-exercise program in preventing or delaying the onset of NIDDM in individuals with impaired glucose tolerance (IGT) in a primary care setting in Europe t - o study the risk factors for progression to diabetes in individuals with IGT  - to asses the effects of the life-style intervention on cardiovascular disease risk factors - to asses the effects of intervention on quality of lifeBrief description: Non-insulin-dependent diabetes mellitus (NIDDM) is an increasingly common disease with large impact on most European populations. NIDDM is characterized by the development complications which give rise to excessive rates of coronary heart disease, peripheral vascular disease, renal disease and visual impairment. Prevention of diabetes has become a major issue both scientifically and from a public health point of view due to the increased morbidity and mortality associated with the disease. The complications of NIDDM can best be postponed by postponing the onset of the disease. The EDlPS study will enrol 900 individuals with impaired glucose tolerance (IGT, WHO criteria) for a 5- to 6-year-intervention period, with annual follow-ups, from 6 European countries. The intervention will be modified to the local conditions. The main issues are reaching and maintaining normal weight, low-fat and high-fiber diet and regular exercise. The 5-year-incidence of diabetes in this risk group is estimated to be 28 %. The power calculation is based on a 30% reduction in diabetes incidence due to a specific diet-exercise treatment. Anthropometric and metabolic parameters will be assessed annually. Also, a blood sample for genetic analysis will be drawn. Carefully designed questionnaires will be used to asses the medical history and quality o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'MONITOR RESPIRATORY HEALTH USING VOICE' (VoiceMed-WomenTechEU) under Horizon Europe.

assistant: **Objectives**

Voice can tell a lot of information about our health. We believe that voice is the new blood for medical diagnosis.Asthma is a long-term disease that affects the lungs and airways. It is one of the most common chronic diseases with 5.8% of the EU population suffering from asthma - ~30 mill people. Doctors have always relied on the patient’s voice as one of the first parameters to assess health. When they talk to a patient, they carefully listen to their breathing, cough, and speech looking for specific signs. However, doctors usually evaluate patients without using any digital solution, leading to a 50% rate in non-well-controlled patients.Deep-tech innovation: VoiceMed uses vocal biomarkers combined with sound analysis and artificial intelligence. Our technology detects subtle signals in the sounds produced by the vocal apparatus. When the association between a signal either a normal biological or pathogenic state is fully validated, these signals become vocal biomarkers. This process allows going beyond the sounds routinely used in medical practice, such as wheezes or crackles, and unlocking a new dimension of biomarkers that can be assessed remotely, instantaneously and with no extra equipment.Women Founders:Arianna Arienzo (CEO) - +6 years experience in business in 5 countries (including Silicon Valley). Entrepreneur in digital health and digital technologies. Listed in Forbes Under 30 in 2022. Contract professor at Cattolica university in healthcare innovation. Msc business administration.Dr. Ayana de Brito (CSO) - +9 years’ experience as a research scientist in computational biology, currently leading our research team. She has skills in scientific practices, scientific writing, pm, strategic planning, data analysis, statistics, data visualization and programming.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Diasporic Constructions of Home and Belonging' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

All over the world, stable concepts of home and belonging have, for a variety of reasons, become the exception rather than the rule. This has led to dramatic cultural, social and political changes and challenges. The study of diaspora and migration has therefore evolved into a burgeoning field of research with an urgent practical relevance. In a wide and sometimes confusing array of approaches it is mainly covered by the humanities and the social sciences. The CoHaB Network unites world-leading institutions in this field in the conviction that interdisciplinary training as well as international and inter-sectoral co-operation are key to any productive study of diasporas. CoHaB gains scope and momentum by its ‘Network of Networks’ rationale, binding together already existing cooperations. It is based on the resolve to strengthen interdisciplinary research in the field with a view to establishing diaspora studies as a transdisciplinary research area in its own right. Training young researchers on the basis of this conviction means to provide them with the opportunity to conduct their work in a variety of disciplinary environments as well as outside a purely academic context. Specifically, CoHaB aims at stimulating and facilitating cooperation by negotiating core concepts between the various disciplines involved among the partner institutions. Each of these disciplines has developed its own, highly sophisticated understanding of diaspora studies, and it is high time that these diverse understandings entered into a sustained dialogue. For this purpose, early stage researchers from various disciplinary backgrounds, but with similar interests in the field of diaspora studies, will join forces to develop their projects on a shared platform. This will assist them in opening the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The Peformance of Democracies' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

This project will use an institutional approach to answer the question why some democracies perform better than others. Democratic systems can be institutionalized in innumerous ways given variation in for example party system, electoral system, type of public administration, judicial control and type of legal system, degree of lobbyism, degree of decentralization, rules for the public budget, possibilities to use referendums, the power of the executive and so on. This huge variation in the institutional configuration of existing democracies will be used for developing a theory for explaining the difference in democracies ability to perform. The motive for this project is the following: Democracy as an overall model for how societies should be governed must be seen as a remarkable success.  Over the last centuries, several waves of democracy have swept over the globe, bringing representative democracy to places where it seemed inconceivable fifty, or even twenty-five years ago. There are certainly many reasons to be enthusiastic about this historically remarkable development.  However, this enthusiasm is dampened by three things. One is that empirical research shows that there is only a very weak, or none, or sometimes even negative, correlation between established measures of human well-being and measures of the level of democracy. For example, communist-authoritarian China now outperforms liberal democratic India on almost all measures of population health. The second reason is that a number of democracies turn out to have severe difficulties managing their public finances in a sustainable way. The third problem is that democracy seems not to be cure against pervasive corruption.  In fact, many authoritarian countries turn out to be less corrupt than many democratic o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Knowledge and Information Stimulating Technology' in the context of a Fifth Framework call.

assistant: **Objectives**

The main objective of the KIST project is to develop the established Treasures programme within the Museum of Scotland's ExhibIT room, through innovative digital exploration of NMS collections using 3D reconstructions, audio, animation and video, adding a new dimension to the visitor experience. The KIST project will also develop and trial the Treasures programme as an on-line resource enabling NMS collections to be explored in detail from anywhere in the world. As part of the on-line development, Treasures will be integrated into the educational environment as a teaching resource for use in classrooms and available to children of all ages.Work description:The project is structured into 4 phases. During the first phase (months 1-2) detailed analysis will be performed on the existing Treasures programme within the Museum of Scotland. Studies will be made on public interaction with the current interface and how effective the programme is at conveying information. Results will be reported. A new interface will be developed based on these results.In the second phase (months 2-5) there will be development of further interactive technology, animation, 3D artwork and digital imagery. New content will be collated and added.In the third phase (months 6-8) user trials of the new interface will take place.During the fourth phase (months 7-12) Treasures will be adapted for Web use. This will be trailed on-line as a general resource and in classrooms as an educational resource. Reports will be produced on the findings.The project's main scope is to expand and improve the established Treasures programme using current and emerging technology, ensuring NMS collections can be accessed by people of all ages and abilities throughout the world. Trials will take place in both the Museum and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Innovative interconnected farm management App and software for precision farming'.

assistant: **Objectives**

Agroptima Farm Manager is a software platform which provides farm management tools to farmers in order for them to be able to keep record of their filed activities and make better decisions based on real cost and productivity data leading to increased efficiency and effectiveness in their business conduct. Data recording, keeping, and analysis are tasks of a relatively high effort when done manually, which is inefficient and results in farmer’s double effort (copying data into spreadsheets). Agroptima Farm Manager allows farmers to collect and record data on a handheld device also offline while in the field and the data collected through the interconnected by sensors equipped with the software agricultural machinery is fed into the server automatically. This allows the users more flexibility and supports the activity of learning from the outputs. The software not only provides overview on current and past farming performance but also provides insights and suggestions, resulting in informed decision making and precision agriculture with an optimised effect on returns and cost cutting (estimated average 12% in cost saving ). Ultimately, with digitised data collection and storage, and automated data gathering from various farm machinery, Agroptima Farm Manager is helping farms to develop productive, sustainable, and resource-efficient approach. Agroptima aims to offer a complete solution for connected farm management through its digital data collection software and connected sensors which collect data from the field. Agroptima’s solution will support farmers making informed decisions and suggest necessary activities and optimised approach to farming to increase efficiency and outputs.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Advanced Pump Engineering for Severe Applications'.

assistant: **Objectives**

Weir Minerals Netherlands (WMNL), a subsidiary of The Weir Group PLC, is a manufacturer of industrial pumps for the mining, energy and minerals and waste processing sectors. WMNL, in collaboration with the University of Strathclyde (UStrath), is proposing an Advanced Pump Engineering for Severe Applications (APESA) EID to improve the total cost ownership of the GEHO slurry pump range. The GEHO range of positive displacement (PD) pumps for transportation of mineral concentrates and feeding of minerals slurries include the largest of this pump type in the world and represents a 65% share of the market.Amidst increased competition from low cost replicators, WMNL has recognised the requirement to extend its technological advantage to maintain its market lead. WMNL does not have the resource to undertake the research required and is proposing the APESA EID to address these challenges through recruitment, training and development of 5 ESRs. The APESA programme will consist of 5 ESR projects in the fields of damage mechanisms, predictive models and damage mitigation, which are largely unexplored areas of fundamental research for PD pumps. The ESR projects will address the challenges faced by WMNL at a level which will represent a sufficient programme to meet the requirements of an individual PhD thesis.The choice of UStrath as the EID Academic Beneficiary stems from an existing partnership between The Weir Group and UStrath. The Weir Advanced Research Centre was established at the UStrath in 2011 and works with Weir Group companies in fundamental research for pumping and flow technology. The centre has 9 ESRs, 2 Experienced Researchers and 10 supervisory UStrath Academic Staff.The aim of the APESA EID is to train ESRs in an industry-centred research environment that will equip
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Cancer Vaccine development for Hepatocellular Carcinoma' (HEPAVAC).

assistant: **Innovation**

Hepatocellular carcinoma (HCC) is the most common primary liver cancer and accounts for about 6% of all new cancer cases worldwide. Given the lack of available effective treatments, the overall prognosis for HCC patients is poor, with a dismal 5-year survival of 5-6%. The main goal of this proposal is to develop a therapeutic cancer vaccine aiming at improving clinical outcome in early-stage HCC patients after loco-regional ablative therapy.HepaVac is an European consortium of academic, SME and pharmaceutical company partners with complementary and substantial expertise in cancer immunotherapy and vaccine development. The main objective of HepaVac is to develop a novel cancer vaccine approach for HCC based on epitopes naturally processed and presented by HLA class I and II (HLA-ligandome), to elicit both CD4+ T helper and CD8+ CTL tumor-specific effector and memory responses. The HCC HLA-ligandome will be identified in primary tumor tissues using a combined and integrated approach, developed and thoroughly validated by Partners #2 and #5. The selected peptide epitopes will constitute the candidate cancer vaccine for HCC, aiming at covering the broadest haplotype diversity with a multi-epitope and multi-TAA strategy. T cell epitopes derived from universal TAA and unique patient-specific mutated antigens will allow the design of a prime-boost vaccine strategy based either on a prime-boost schedule made of an “off-the-shelf” T cell epitope cocktail or on a schedule where the boost is complemented by a “personalized” T cell epitope cocktail. Both epitope cocktails will be adjuvanted in a novel and potent immunomodulator developed by Partner #6. Such a vaccination strategy will be tested in a randomized controlled multi-center phase I/II human clinical trial, assessing as pr