RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Re-orienting development: the dynamics and effects of Chinese infrastructure investment in Europe', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

REDEFINE will examine what Chinas rise means for how we understand global development and, specifically, Europes place in it. After 15 years of going out to access raw materials and new markets, often in the global South, China is making assertive moves into developed economies, which were boosted by the Belt and Road Initiative linking China to Europe. At the same time, many European economies stagnated following the 2008 financial crisis with governments cutting infrastructure investment and seeking alternative sources of finance. China now sees Europe as fertile ground for new infrastructure investment, yet many European firms and governments are ill-equipped to deal with these political and economic changes. The first wave of Chinese internationalisation into the global South has been analysed largely from the perspective of international Development Studies. In the current phase, Chinas move westwards radically questions the meanings and loci of development. REDEFINEs innovation is to use insights from international development to interrogate Chinese engagement in the heart of Europe and by doing so re-orient the Eurocentric debates in the social sciences around how we define and delimit development, who drives these processes, and what it means for societies affected by such investments. REDEFINEs aims require a disaggregated approach to unpack project-by-project effects, which will be undertaken using an assemblage methodology. Through comparative, ethnographic case studies in the UK, Germany, Greece and Hungary REDEFINE will produce fine-grained analysis to understand the rationales for Chinese investment in Europe, the geopolitical dynamics surrounding these financing streams, the structuring of projects, and how they interface with national and local developme
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Genome scale analysis of hte immune response against pathogenic micro-organisms; leading to diagnostic and vaccine candidates and development of an integrated micro array platform for clinical use (MICROBEARRAY)' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

The genome sequences of microbial organisms responsible for diseases of world-wide medical importance have been sequenced or will be available in the near future. Technologies for producing large numbers of proteins have been developed and high-throughput assays such as protein micro arrays have been clinically validated for detecting the presence of antibodies, in serum, directed against microbial antigens. These achievements offer the opportunity of investigating the natural immune response against the w hole proteome of a variety of micro-organisms. Powerful combinations of genomic information, molecular tools and immunological assays are becoming available to help identify the antigens that function as targets of protective immunity or could be used as m arkers for serodiagnosis. We propose here to identify in micro-organisms of great medical relevance (M. pneumoniae, C. pneumoniae, L. pneumophila, coronavirus spp and P. falciparum), a large collection of surface and secreted proteins as well as putative e ndotoxins. This protein repertoire will be produced as recombinant molecules or as sets of overlapping synthetic peptides and printed on array slides. The serum reactivity of groups of individuals with proven historyof exposure to the selected micro-organi sms will be analysed against the arrayed proteins to identify diagnostic markers and correlates of protection. This project will significantly expand the SMEs bank of Intellectual Property and contribute to expertise within the RTDs. It is anticipated tha t the proposed work in high throughput protein expression, software analysis, surface peptides synthesis, protein and peptide surface capture, and array reader instrumentation will create an integrated platform of great commercial and research value. Fina lly i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Development of mixed starter cultures for the production of high quality cocoa in West Africa' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Export of cocoa plays a significant economic role in West African countries like Cote d'Ivoire, Ghana and Nigeria, the major cocoa producing region in the World. Fresh cocoa beans have to go through a fermentation and drying step to obtain the desired characteristic 'cocoa flavour'. Traditionally, cocoa beans are fermented through a spontaneous, indigenous fermentation with no control of the microorganisms present. As a consequence, the quality of cocoa varies. These variations negatively influence the price and thus the economy of the cocoa producing countries. The main purpose of the proposal is to improve the quality of cocoa through the development of starter cultures to control the fermentation. the performance of potential starter cultures will be examined in micro fermentations using advanced methods including GC-MS, GC-olfactometry and HPLC. The key deliverables are : Development of one or more starter culture consortia for the production of cocoa of consistent high quality; Identification of the roles of specific microorganisms in the cocoa fermentation; Investigation of microbial interactions during the fermentation of cocoa. The project proposed contains highly innovative aspects as microbiologically well characterized starter cultures with proven technological properties for the fermentation of cocoa are developed for the first time. The research training is multi-disciplinary, including advanced state-of-the-art methodologies, complementing the skills of the applicant and making the applicant highly qualified to pursue his line of research into fermented foods. The project addresses important community policies, most importantly, policies on development co-operation, allowing transfer of knowledge, but also policies on consumer protection. The possibility t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Deciphering the role of the Mycobacterium tuberculosis exometabolome in mycobacterial virulence' (MIMETIC).

assistant: **Concept**

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), exhibits an intracellular lifestyle, thriving within host macrophages. This remarkable ability to evade macrophage-mediated killing and withstand the challenges posed by the host environment hinges largely on its exceptional capacity to adapt its metabolism in response to the diverse conditions encountered during infection. Despite progress, our comprehension of Mtb metabolic adjustments in these circumstances remains limited.Preliminary investigations conducted within the host laboratory have unveiled that Mtb releases a multitude of small, soluble molecules into its extracellular milieu when cultured in vitro. These metabolites potentially exert a substantial influence at the host-pathogen interface, subsequently shaping the delicate equilibrium established between the bacterium and its host throughout the course of infection. This proposal is centered on elucidating the role of Mtb exometabolome at host-pathogen interface, with the overarching objectives of (i) advancing our insight into Mtb metabolism and (ii) pinpointing potential novel virulence determinants that might be secreted by the microorganism.The primary phase involves the comprehensive identification and quantification of metabolites present in the bacterial culture medium. This will be achieved through untargeted metabolomics methodologies, primarily utilizing NMR and mass spectrometry. Subsequently, the metabolic pathways governing the biosynthesis and secretion of these metabolites will be characterized. This investigation seeks to unravel the underlying metabolic drivers facilitating the release of these compounds. The culmination of this project involves exploring the impact of a subset of significant metabolites on the phys
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Macroscopic properties of interacting bosons: a unified approach to the Thermodynamic Challenge'.

assistant: **Concept**

Interacting bosons are unique quantum systems, whose low temperature phases exhibit fascinating quantum mechanics effects at a macroscopic scale. In the past two decades, the mathematical understanding of these systems improved tremendously. However, their behavior in the thermodynamic limit is still poorly understood, although this is the appropriate large scale limit to prove the emergence of scaling laws and universality, as well as to investigate the occurrence of phase transitions. MaTCh aims at investigating the low energy properties of interacting bosons in the thermodynamic limit, and at gaining a mathematical understanding of the emergence of correlated phases, in the form of Bose-Einstein condensation and quasi-long range order, as well as of their instabilities, due to thermal fluctuations or three-body recombination effects of Efimov type. Our plan is to exploit scaling limits as a framework to identify and overcome, one at a time, the mathematical obstructions that currently prevent us to control the system at finite density in the thermodynamic limit. In order to make progress on this program,  MaTCh will introduce novel mathematical methods, inspired by renormalization group approaches and grounded in the second quantization techniques developed by the P.I. and collaborators, valid on an increasing sequence of scales.Ultimately, the research led by MaTCh will lay the foundation for the rigorous description of several phenomena which are at the frontiers of present theoretical and experimental research, where collective excitations of quantum systems are described in terms of emergent Bose gases, such as in the BCS theory for superconductivity, the molecular description of strongly interacting Fermi gases, and the spin-wave theory for quantum magnetism.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Immunological mechanisms of post-stroke dysfunction and recovery of neurovascular coupling' (VasoRecovery) under Horizon 2020.

assistant: **Objectives**

Ischemic stroke is one of the most common causes of disability and death in the EU. Improvements in treatment and prevention of ischemic stroke have reduced this burden, but consequently, patients living with chronic post-stroke conditions are increasing in number. Addressing this emergent public health problem will require novel rehabilitation interventions at the clinical level. Recovery after stroke correlates closely with cerebral vascular function, such that patients with dysfunction of vascular reactivity exhibit significant functional impairment. On the other side, inflammation in autoimmune and infectious diseases has been demonstrated to also result in dysfunction of cerebral blood flow regulation. However, a potential mechanistic link between the post-stroke inflammatory response and chronically impaired vascular dysfunction after stroke has yet not been studied in detail. Therefore, the goal of this project is to identify the impact of cerebral, neuroinflammatory and systemic innate immune responses to vascular dysfunction after experimental stroke. To achieve this goal, under the supervision of Dr. Arthur Liesz at the Institute for Stroke and Dementia Research, I will learn to specifically target immune cell populations, analyze chronic functional outcomes after stroke and gain expertise in performing in vivo multimodal imaging. Dr. Liesz runs an interdisciplinary highly collaborative research program within the conceptual framework of stroke-immunology. I will be able to contribute my previously acquired expertise in neurovascular function and in vivo vascular imaging for the success of this project. The Marie Sklodowska-Curie individual fellowship (MSC IF) will allow me to obtain the required methodological knowledge, access to critical infrastructure and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Fail-operational safety – making autonomous vehicles a reality' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

We have seen a revolution in autonomous driving technology. Today, more than 75% of newly registered vehicles have some level of driver assistance. However, despite vast strides in new AI and sensing technology, fully autonomous vehicles are yet to be realized because the actuator technology for the safety-critical steering and braking systems are not mature enough to guarantee fail-operational capability.Chassis Autonomy has developed the first fail-operational steer-by-wire system, which is suitable for fully autonomous vehicles. It is the final step toward fully driverless vehicles (i.e., no steering wheel) and will unlock the next wave of automotive driving.We have completed a series of early prototyping and validation activities and we are now seeking the support of the EIC to finalize our technology and go to market in two years to meet the roadmaps of the leading autonomous mobility developers.


**Keywords:** Autonomous Driving
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Molecular control of lateral initiation' to be submitted under Fourth Framework.

assistant: **Abstract**

The LATIN programme's objective is to improve our understanding of the regulation of branching in plants using Arabidopsis as our model. Despite its importance, little is known about the molecular mechanisms controlling root and shoot lateral initiation and maturation. Physiological studies indicate that the plant hormones auxin and cytokinin are of central importance. Arabidopsis molecular genetics provides a powerful approach to dissect phytohormone-regulated branching. which has already resulted in the identification of a selection of root and shoot branch mutants and their genes by members of the LATIN programme. The information and molecular tools which arise from our studies of Arabidopsis will underpin our efforts to manipulate branching in selected transgenic crops. Eucalyptus, poplar and oil-seed rape are important European crops, providing materials for the paper, construction and chemical industries respectively. The ability to engineer novel branching phenotypes within these target crops will have major economic consequences for agronomically important qualities such as plant propagation. processing and yield. The complexity of branch control demands a multi-disciplinary approach in partnership with industry that would be impossible to achieve in any individual research group or company. The partnership consists of a truly pan-european collection of experts specialising in the fields of: A. Arabidopsis Molecular Genetics - Catherine Bellini & Jean-Denis Faure, INRA, Versailles, France (INRA); Malcolm Bennen, University of Warwick, UK (UW); Ottoline Leyser, University of York (UK); Klaus Palme, Max-Delbrucke-Laboratory Koln, Germany (MPG.MPL); Burkhard Schulz, University of Koln, Germany (UC). B. Plant Hormone Quantification - Goran Sandberg, Faculty of Fores
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Development of relaxor based improved piezoelectric single crystals (DORIS)' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

Piezo ceramic materials have many applications due to their inherent efficiency. particularly they can be used in medical and health applications for ultrasonic imaging and in fields requiring sensors, actuators or filters. During last decade, research to improve piezoelectric properties has been attempted with limited success because the intrinsic physical limits of such materials. Recently, some fundamental work in Japan and USA have demonstrated the feasibility and performance of perovskite-type single crystals containing lead oxide. Unfortunately, these crystals are difficult to grow by conventional methods which will limit feasible manufacturing. However, because of their exceptional characteristics, the consortium proposes to investigate modified crystal growth technologies of leaded and environmentally friendly lead-free compounds and to validate the advantages of using such crystals.-Innovative crystal growth routes adapted to the growth of piezoelectric single crystals;-Single Crystals demonstrators, size ranging from few mm3 to more than one cubic centimetre;-Advanced transducer design and complete ultrasound demonstrators manufacture for single crystal-based devices.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Synthesis of molecular probes for cancer research based on priviliged natural products through a novel enantioselective oxidative arylation technology'.

assistant: **Objectives**

Enantioselective catalysis continues to be a necesarily expanding part of Organic Chemistry and Synthesis to be able to provide the enantiopure compounds that Society demands in a straightforward and sustainable way.This research proposal is aimed at doing so through the development of new enantioselective oxidative arylation reactions a completely unprecedented research field. Moreover, the molecular structures and synthetic targets have been selected in close collaboration with the group of Dr. Murrell at CRUK Cambridge. This collaboration is aimed at understanding the processes of cancer generation and growth at the molecular level through development of small molecule histone methylation and acetylation modulators. To study such processes a priviliged and synthetically challenging familiy of natural products is targeted: the pyrroloindole alkaloids. Development of molecular probes inspired by these products and demonstration of the total synthesis of some members will be accomplished through the development of appropiate chemical tools. The synthesis of these compounds will enable multidisciplinar research to study the particularities of oncogenesis.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Specific and efficient second generation gene delivery tools'.

assistant: **Innovation**

The aim of the proposed project is to prepare a CRAFT-proposal aimed at significantly improving the efficiency of gene transfer and gene expression for therapeutic applications. Austrian Nordic Gems and Agrobiogen GmbH intend developing an improved transfer and expression system based on retroviral vectors. Central to this proposal is the concept of directed molecular evolution, where libraries of vector sequences are randomly mutated. Novel vectors are introduced into cells in competition and the most suited vectors are the ones that best establish themselves. The concept will be taken further in that vectors that retain the ability to replicate will be modified, allowing multiple rounds of selection. Mutations identified using this molecular evolution system that lead to improved vector characterisations can be regarded as versatile modules that can increase the efficiency and safe of a whole range of vector systems both. Whilst both partners have resources to conduct some of the basic research and most of the developmental and exploitation aspects of this project, neither of the two partners has sufficient expertise in the areas of retrovirus-based molecular evolution technology, identification of sustained expression features, ex-vivo transudation of haematopoietic cells and models for systemic vector administration in vivo to complete the pro.