RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Spin transport and spin-orbit phenomena in 2D materials', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

We live in a technological world where usage of electronic devices for information technology is an integral part of everyday life. Present and future technological progress requires miniaturization of such devices, continuous improvement of their performances and decreasing of energy consumption. Spintronics, a growing research field based on the manipulation of the spin of the electrons, offers devices that fulfil these needs. However, a new generation of proposed spintronic devices are yet to be realized due to the lack of a tuneable spin transport channel. The major obstacle to build such channel is that the transport and the manipulation of spins (which require weak and strong spin-orbit coupling, respectively) in the same material are mutually exclusive. 2DSTOP addresses this problem by exploiting the unconventional spin-dependent properties of the transition metal dichalcogenides. In these two dimensional (2D) layered materials, electrically tuneable spin transport in the presence of strong spin-orbit coupling is theoretically predicted. 2DSTOP envisions the experimental realization of such predictions. Combining these materials with other 2D materials such as graphene and hexagonal boron nitride, this proposal plans to investigate not only the spin transport, but also some of the exotic spin-orbit-related phenomena. This way, the project aims at acquiring scientific knowledge with potential technological applications to be useful for both academia and industry. Moreover, the ultimate goal of 2DSTOP is to offer high-quality interdisciplinary research training for an aspiring young researcher helping him to build a promising scientific research career.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Hepatitis C virus virion-bound proteins: identification in clinical samples and in vitro dissection of their importance in the viral life cycle' under Seventh Framework.

assistant: **Concept**

The emergence of hepatocellular carcinoma (HCC) has prompted a search for a thorough understanding of the biology of one of its major causative agents, the hepatitis C virus (HCV). Half of genotype 1 patients, the most numerous in Europe, do not respond to treatment, putting them at risk for cirrhosis and HCC. HCV particles acquire via budding and encapsidation cellular proteins. There is mounting evidence on several viral species that virion-bound proteins are prone to be involved either at the replication, budding/egress or entry/release steps of the viral cycle. Identifying such targets may yield ideal candidates for gaining insight on the dependence of HCV upon a restricted subset of host proteins, therefore providing refined sets of genetically stable targets for therapy. This project’s goals are to set up adequate conditions for robust and reproducible purification of HCV virions in clinical samples, followed by the identification of their HCV-bound host proteins and the characterization of their functions. Proteomics profiling of HCV particles purified from clinical samples will be overlaid with proteins identified and characterized in cell culture-grown HCV particles during my post-doctoral training, using clinical biomarker discovery grade criteria. Targets identified in both samples sets will be subjected to in vitro investigations using HCV-replicating cells. Conventional biochemical and imaging methods will be used in order to: (i) ascertain their physical association with HCV virions; (ii) define the modalities of their interaction with HCV proteins; (iii) decipher the topology and subcellular localization of their association with HCV proteins and virions; (iv) quantitatively assess their functional involvement in particle budding, egress or secretion and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Development of a Synergistic Catalysis Protocol for the Enantioselective Functionalisation of Aldehydes' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The paradigm of organocatalysis, wherein small organic molecules serve as reaction catalysts, has emerged as a valuable source of innovation over the past 15 years, delivering over 200 new asymmetric transformations. The MacMillan group have consistently been at the forefront of organocatalysis research, and to date have pioneered over 30 catalytic transformations of immense practicality and synthetic utility.Recently the group have popularised a powerful strategy for enantioselective catalysis based on the synergistic merger of organocatalysis and transition metal catalysis. The concept of synergistic catalysis, which draws inspiration from biosynthetic models, envisions the simultaneous activation of two reactants through the productive merger of two separate catalytic cycles. Working within the pioneering research group of Prof. David MacMillan, the Outgoing Phase project aims to further develop the concept of synergistic catalysis. In particular, a powerful new strategy for the enantioselective functionalisation of aldehydes using boronic acids as coupling partners will be developed based on the merger of organocatalysis and transition metal catalysis. The Return Phase project seeks to develop the high-profile area of transition metal catalysed C-H bond activation. The capacity to activate a specific 'inert' C-H bond and transform it into a more versatile functional group represents the ultimate synthetic transformation and offers significant benefits to organic chemists.The concepts described are expected to be widely adopted by practitioners of chemical synthesis throughout the realm of biomedical research, thereby greatly benefiting European science. The importance of the research topics and high profile collaboration between two world-class research institutes w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Laser Interferometer for High Quality Manufacturing Industry.', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Foreseen ResultsA novel laser-frequency stabilization system using FLC cell will be developed, which significantly reduces the size of the laser head and the price of the interferometer. The working prototype of a laser interferometer will be presented and evaluated in the industry.The frequency stability will be better then 0.01 ppm. The instrument will be equipped with a Software Package for determining positioning errors in accordance with ISO230 and national norms of CIS country. Software will automatically measure parameters of selected items of the machinery, eliminating the need of manually triggering the data acquisition during determination of positioning errors. Additionally, optics for checking angle, straightness, parallelism, flatness, squareness, and dedicated software packages will be developed.The instrument construction and pricing will open the way to its application in CIS industry. The software package will assist CIS industry in the introduction of the ISO230 standard.The aim of the proposed project is to develop a working prototype of a laser interferometer of a novel construction and open the way to its industrial production. Such an instrument allows high accuracy length measurements, which is the key demand of machine-tool industry of CCE/NIS countries during the process of conforming to EC norms.The central element in the laser frequency stabilization system will be a ferroelectric liquid crystal cell acting as a fast optical polarization switch and control unit. Such a design assures a very high accuracy of the frequency stabilization and reduces the production costs of the instrument.The project joins five partners, each having outstanding experience within their field of research, which assures that the objectives of the proposed project wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Enzymatic up-grading of wool fibres'.

assistant: **Innovation**

The market value of wool is limited by the fact that consumers place increasingly high demands on machine washability and soft handle. Felting shrinkage, which is a typical property of wool due to the configuration of the scales of the wool fibre, is a serious problem, especially during washing. Chlorination, followed by polymer deposition, is commonly used to modify the scales of wool fibres in order to confer shrink-resistance, but this involves major drawbacks with respect to contamination of the wastewater with absorbable organic chlorides (AOX) and the environment.The main innovative aspect of this proposal is to develop novel, genetically engineered proteases with increased molecular size for producing shrink-resistance and other improved properties on wool fibres and fabrics. The project is to develop machine washable wool by limiting the enzymatic degradation of wool fibres to their cuticle scales. Furthermore, other new environmentally friendly processes including efficient bio-scouring and bio-finishing processes, and low temperature dyeing processes for wool fibres will be developed via treatments with a range of specifically engineered proteases. The application of different specifically engineered proteases will also be extended to new detergent formulations for industrial and domestic washing and wool carpet cleaning and thus improve hygienic aspects of wool based textile materials.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'TRAF-STOP therapy to reduCe inflammation in athERosclerosis.' under Horizon 2020.

assistant: **Concept**

Atherosclerosis, the underlying cause of the majority of cardiovascular diseases, is a lipid driven, inflammatory disease ofthe large arteries. Despite a 25% relative risk reduction achieved by lipid-lowering treatment, the vast majority ofatherosclerosis induced cardiovascular disease risk remains unaddressed. Therefore, characterizing mediators of theinflammatory aspect of atherosclerosis is a widely recognized scientific goal with great therapeutic implications. Blocking theco-stimulatory CD40L-CD40 dyad reduces atherosclerosis. However, long-term inhibition of CD40L or its receptor CD40results in suppression of the immune system and poses a risk for thromboembolic events. Therefore, we focused on thedownstream signaling pathways of CD40, and found that the interaction between CD40 and TNF-receptor-associated factor6 (TRAF6) is the driving force for atherosclerosis. Using virtual ligand screening, we identified several small moleculeinhibitors termed TRAF-STOPs that were modeled to bind to the CD40-binding domain of TRAF6. TRAF-STOPs significantlyreduce (existing) atherosclerosis and treatment was well tolerated. The first toxicology results in mice show that there are noside effects. Here we pursue the hypothesis that TRAF-STOPs are excellent candidates to pass the translational pipelinetowards a clinical application to treat atherosclerotic cardiovascular disease. Prof. Lutgens is one of the founders of therecently established start-up company Cartesio Therapeutics to be able to valorise our novel TRAF-STOPs. By the end ofthe PoC grant, we expect to have an oral drug available and to have completed toxicology and bio-distribution analysis in alarge animal model (mini-pig) and have tested TRAF-STOPs in a pig model of atherosclerosis. This way, we hold a solidbusines
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Innovative WAter recoverY Solutions through recycling of heat, materials and water across multiple sectors' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

The European Green Deal, an ambitious growth strategy aligned with the Sustainable Development Goals (SDG), calls for the mobilization of the industry. Indeed, while important steps have been taken in the past, the annual global extraction of materials tripled in the last 50 years and is expected to increase further. The dual transformation, green and digital, place special emphasis on resource and energy intensive sectors. Furthermore, the expected zero pollution action plan for air, water and soil will enforce this transformation. In this changing environment, industry will have to adapt swiftly and decisively but the ease and smoothness of this transition is up for debate. Solutions that increase costs and impede productivity will face substantial resistance. There is a pressing need for new technologies and approaches that complement economic growth and productivity while firstly addressing environmental challenges. iWAYS is a step in this direction, featuring a wide array of technologies that are non-disruptive and applicable in any industry with wastewater and gaseous emissions. While the concept of water and heat recovery have been demonstrated and widely applied, in iWAYS a unique approach is taken, focusing on until now impossible streams to address and building synergies between heat and water reclamation and exploitation. The project also addresses several issues afflicting commercial technologies (such as Reverse Osmosis and Membrane Distillation) through innovative and enabling approaches.


**Keywords:** Water material energy recovery
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Powder is the only app offering a complete turnkey solution to automatically detect the best gaming moments, earn rewards from  quests and challenges, and compete with other gamers.' to be submitted under Horizon Europe.

assistant: **Abstract**

Powder is the only app offering a complete turnkey solution to automatically detect the best gaming moments, earn rewards from quests, and compete with other gamers.As a deep tech company, we invest in self-supervised machine learning techniques for highlight detection, surpassing state-of-the-art.In a market set to surpass three billion gamers by 2023, with steady yearly growth in the last seven years (5.6%), Powder brings disruptive innovation to the market by empowering every gamer to become a content creator and socialize with their peers through clips and challenges. As their virtual lives get richer, and lifestyle gaming becomes a daily activity, gamers are increasingly looking for ways to make the most of their meaningful moments in the virtual worlds.Powder empowers every gamer with a platform that puts the users interests at his core, challenging the existing social media models by proudly committing to delivering a stronger, fairer, more digital, and more resilient Europe.


**Keywords:** content creation,Game detection AI,E-sports,recommendation system,moderation AI,game highlights,editing engine,metadata,Convolutional neuronal network,self-supervised learning,Emotions recognition,Web,Video editing,PC,mobile,cross-platform,creators economy,gaming content,metaverse,disruptive innovation,videogames,machine learning,Game Studios,artificial intelligence
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Decoding of grasping movements from frontal and parietal cortex for the development of a neural prosthesis' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

The use of the human hand plays a central role in human motor behaviour. Several specialized areas in the pre-motor and parietal cortex play a dominant role for the high-level preparation of hand movements, which involves the transformation of visual information and volitional signals into motor plans that can be readily executed. The capacity to plan hand movements is preserved, even if the neural pathway to execute these motor signals is disrupted, like in patients with spinal cord injury or stroke, where neural commands can no longer reach the hand. We propose to investigate in non-human primates how these hand-planning signals could be read out and interpreted for the control of a prosthetic hand.In Aim 1, we will investigate the fundamental operation and interaction of two specific brain areas, the anterior intra-parietal area (AIP) in the parietal cortex and the area F5 in the ventral pre-motor cortex that both generate early hand grasping instructions. We will record spiking activity and local field potentials (LFPs) simultaneously from both areas while animals perform a delayed grasping task, in which objects can be grasped with either a precision grip or a power grip and in 5 different hand orientations. By correlating the neural responses with each other and with the animal's behaviour, we will determine how high-order grasping plans are encoded in AIP and F5 and how these areas interact to generate grasping movements.In Aim 2, we will continuously read out and decode these high-level grasping signals for the control of a robotic hand. We will permanently implant up to 100 recording electrodes in AIP and F5 and continuously record spiking activity and LFPs to predict the animal's plan to grasp, which will be used to control a simple robotic hand. This pro of c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Autonomous Robotic System for the Inspection of Mooring Chains that Thether Offshore Oil Gas Structures to the Ocean Floor.'.

assistant: **Concept**

Floating platforms for plant, machinery and accommodation are being used increasingly in offshore oil and gas production. These permanent floating production platforms must be moored to the sea bed. The integrity of the mooring system consisting of chains is critical, because the consequences of failure could be oil pollution on a catastrophic scale. There is therefore an urgent need to improve the integrity management of mooring systems. One issue is the inspection of chain links. Regulatory visual inspection is currently done with the cable chain brought up on deck, or, for greater sensitivity to defects using non-destructive tests (NDT), with the cable chain taken on-shore.Increasingly, interim swim-by inspections of the chain in-situ are being conducted from Remote Operated Vehicles. The inspection however is unreliable, susceptible to human error, because of the hundreds of metres of chain involved and the short times allowed for inspection. Industry recognises the need for more effective inspection. The inspection system proposed here will test the chains in situ, above and below water, will be automated and will be sensitive to fatigue cracks, corrosion, bent chains and where present, loose studs.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'New Century of Superconductivity: Ideas, Materials, Technologies' in the context of a Seventh Framework call.

assistant: **Objectives**

This project is devoted to the new trends in superconductivity. It contains both experimental and theoretical component. We intend to realize the new superconductive nano-systems with high critical parameters, to study the possibility of superconductivity in the system of relativistic electrons in graphene, pumping effect in Josephson systems, a new mechanism of interaction between electrons of two Fermi seas, mediated by excitations of a Bose-Einstein condensate of exciton-polaritons, to develop a new diagnostic methods based on the fluctuation spectroscopy, to apply them for investigation of the pseudo-gap state properties of HTS. In the present project the experts in superconductivity of the highest international recognition take part side by side with young researchers from five institutions of four countries. The network institutions are located in the EU countries (France, Italy) and in the Eligible Third Countries of the former Soviet Union (Russia, Ukraine). Each of them has its own specialization and is related with others by virtue of already existing traditional collaborative links, partially supported by different national or bilateral programs. In the course of the project we are going to exploit the existing collaboration links and to create the new ones between partners. The main goal of the project is studying and optimization of the mechanisms of realization of the superconductivity in novel systems and materials. Series of bilateral visits, training workshops and meetings are planned for this purpose.