RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Enantioselective Isocyanoacetate Addition Reactions under Cooperative Base and Lewis Acid Catalysis'.

assistant: **Concept**

Enantioselective Isocyanoacetate Addition Reactions under Cooperative Base and Lewis Acid Catalysis. Enantiomerically pure substances with the capacity to simultaneously activate two reagents towards one another, offer numerous opportunities for the discovery of powerful, asymmetric bond forming reactions. When a compound possesses a combination of Brønsted (or Lewis) basic and Lewis acidic sites, has a well-defined chiral pocket constructed around a fairly rigid skeleton and appropriate distances between the two activating groups, the templating of a pronucleophile (NuH) and an electrophile via a ternary complex can lead to excellent levels of enantio- and diastereocontrol in efficient addition reactions at low catalyst loadings. The design and synthesis of new, readily accessible catalytic systems plays a pivotal role in this field of research allowing the discovery of useful synthetic pathways, rapid optimization of the ligand canopy and a better understanding of the mechanism and origins of stereocontrol. During this Fellowship we wish to develop new and synthetically powerful enantioselective inter- and intramolecular addition reaction of isocyanoacetate pronucleophiles under cooperative base and Lewis acid catalysis. In particular we  wish to investigate the addition chemistry of imines and electron deficient double bonds, as well as intramolecular additions to pendant alkyne functionality, using novel aminophosphine precatalyst/transition metal ion combinations. Not only will these reactions constitute important developments in the field but the product structures are often biologically relevant, thus lending the chemistry to important synthetic applications.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Highly scalable, small, and inexpensive high resolution 3D Light Detection and Ranging System (LiDAR) for the mass market of Automated and Autonomous Vehicles.' (LiDAR).

assistant: **Innovation**

Blickfeld GmbH developed a novel scalable core technology for high-performance LiDAR (light detection and ranging) sensors. The innovation allows the mass production of robust, small and inexpensive LiDARs paving the ground for autonomous cars that are dependent on reliable and affordable perception sensors. This breakthrough core technology is based on micro electro mechanical system (MEMS) mirrors, merging the best of silicon microfabrication and established LiDAR concepts. By the MEMS technology the technology is highly scalable and closes the gap between today’s high-cost systems and the automotive mass-market needs. Blickfeld’s LiDAR reduces costs from more than €10,000 to €400 for one LiDAR sensor. Currently no economic automotive LiDAR with comparable performance is available.Within the planned EU project, Blickfeld strives for reaching TRL 9. For this purpose CE, FCC, CCC, eye security and the automotive security level ASIL-B will be attained. Blickfeld develops a profound commercialisation plan for the innovation addressing the erupting markets of Europe, North America and Asia in the first step. The novel LiDAR P1 addresses an exploding market because LiDAR scanner technology is an enabler for autonomous cars. Target markets for the Blickfeld LiDAR scanner are automotive Tier 1 companies with a total addressable market volume of €29.0 billion in 2030. With the P1, regulatory and technical requirements by the automotive companies are solved for the first time in total. In the beginning, the P1 LiDAR is incorporated in cars with SAE levels up to 3. In the next step autonomous vehicles with SAE levels of up to 5 are equipped.Blickfeld strives for a cumulated turnover of €116 million in the first three years after the end of the project – that is 37 times the proj
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Differentiation of GABAergic interneuron subtypes in the mouse cerebral cortex', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

GABAergic interneurons of the mammalian cerebral cortex display a variety of morphological and physiological behaviors that are thought to be crucial for both the development and the function of mature cortical circuits. Defects in cortical inhibition have been implicated in neurological and psychiatric disorders such as epilepsy, depression, anxiety, addiction, schizophrenia and autistic disorders. Research over the past decade has shown a common embryonic origin for most mouse cortical interneurons in the ganglionic eminences (ventral regions) of the telencephalon, from where they tangentially migrate to reach the cortex. Within the cortex, interneurons integrate into the local circuitry while they develop mature and distinct morphological and physiological properties. To achieve specific functions, different interneuron subtypes have to growth and pattern cell-type-specific dendrite and axon arborizations, and establish specific patterns of synaptic connections. The genetic programs that control the differentiation of distinct interneuron subtypes in the developing cerebral cortex are largely unknown. This proposal is aimed to understand how regulatory networks of transcription factors acting during the prolonged period of cortical interneuron differentiation, from progenitors in the ganglionic eminences to mature cortical interneurons, specify distinct cell fates. In particular, we will use in vitro (RNA interference) and in vivo (mouse models) approaches to understand the regulation and maintenance of terminal interneuron differentiation, including the pattern and growth of axonal arborizations. These studies will help to elucidate the mechanisms that regulate the development and function of the cerebral cortex in normal and pathological conditions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Human transmissible spongiform encephalopathies : the european diagnostic laboratory (TSELAB)' (TSELAB) targeting Fifth Framework.

assistant: **Abstract**

There is a lack of diagnostic procedures able to identify people during the cud incubation time, and uncertainty with the clinical diagnosis of human Tees. In response, TSELAB is proposed as multidisciplinary European diagnostic TSE laboratory without walls. It aims to develop and apply clinical and novel laboratory diagnostic procedures to identify preclinical and clinical phases of various Tees, by examination of various tissues, preferably of readily accessible fluids such as blood or urine, and to identify cud possibly emerging also in non-129MM gene-types. TSELAB effectively complements existing clinical-epidemiological and pathological-pathological networks in Europe that will provide material for investigation. Partners include the most experienced European groups for TSE diagnostic procedures, have developed the novel PMCA, SIFT, ELISA, controlled degradation of Prepress and pups methods themselves, and can be expected to achieve project aims.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Minimizing Activity and Dose with Enhanced Image quality by Radiopharmaceutical Administrations' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

MADEIRA aims to improve 3D nuclear medical imaging technologies significantly. Achievements will be made in terms of reduction of radiation exposure, increase of spatial and temporal resolution. In consequence, the applied techniques will offer better and more detailed pictures for diagnosis obtained with less exposure to radioactivity. Due to the introduction of new diagnostic procedures such as CT, PET and SPECT, the individual dose caused by medical exposures rapidly grew in the last years. This is especially a subject to radiation protection for nuclear medical diagnosis since in this case radiopharmaceuticals are administered to the patient meaning not only a radiation exposure to the unhealthy tissue but also to the healthy tissue of large parts of the body. When dealing with cancer any improvement in the efficacy and availability of proper diagnostic procedures turns out into a benefit for the patients. Early diagnosis reduces mortality and other serious implications like loss of quality of living or high therapy costs. Diagnosis that provides information about - activity of the cancerous tissue - in what 3D region of the cancer and - what kind of cancer to be treated in each specific case is very important. 3D functional nuclear medicine imaging satisfies the above requirements. Especially the combination of today’s systems with CT scanners allows simultaneous acquisition of anatomical and functional information. MADEIRA will improve the efficacy and safety of 3D PET and SPECT functional imaging by optimising the spatial resolution, the signal-to-noise ratio and the knowledge of the temporal variation of the radiopharmaceuticals’ uptake in and clearance from tumour and healthy tissues and evaluating the corresponding patient dose. By this approach to an optimize
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Where life science meets our daily life' in the context of a Horizon 2020 call.

assistant: **Objectives**

acib is planning a second edition of an open event for the young general public in the frame of the European Researchers' Night in Austria. The first edition was held as a virtual event in 2020. In a next step the event is planned onsite in order to intensify the experiences in identifying connections between research and our daily life.Under the roof LifeisScience the visitors gain insights into the every-day work of researchers in the manifold fields of biotechnology and related disciplines as well as its impact to our daily life. LifeisScience offers to discover scientific contents along three dedicated story lines by visiting laboratories, contributing in experiments, interrogating scientists about puzzling questions, exchanging ideas in debates, participating in open innovation science, watching demonstrations and learning more on recent scientific discoveries. The story lines are food technology, waste management & renewable resources and health. The different activities intend to allow visitors to identify connections between research and our daily life. The principle of collecting stamps for each activity and receiving a gift for absolved story lines aims to drive visitors' motivation and, thereby, some may discover their passion for science and their preference for a research career.


**Keywords:** life sciences, science communication, biotechnology, MINT disciplines, open innovation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Enabling digital technologies for Holistic Health-lifestyle motivational and assisTed supeRvision supported by Artificial Intelligence Networks' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

H2TRAIN proposal is funded on the sixth edition of the Electronic Components and Systems (ECS) Strategic Research and Innovation Agenda (ECS-SRIA) topics and major challenges for enabling digital technologies in holistic health-lifestyle supported by artificial intelligence (AI) networks. Biosensors for e-health and smart tracking of sport and fitness are a class of devices that is dominating the consumer and professional market with an unprecedented growth. Despite the impressive capabilities of recent approaches, several prospective revolutionary improvements are still open points, mainly in relationship with four factors: sensing new biosignals and tracking new activity patterns; improving battery lifetime and energy management for continuous use; and secure, reliable and efficient data analysis with AI algorithms and connectivity with the IoT.H2TRAIN aims at advancing the state of the art in this respect, taking profit from the remarkable properties and synergistic potential of one-dimensional (1D) and two-dimensional (2D) materials (1DM and 2DM), enabling more sensitive, efficient, and miniaturized biosensing capabilities within the established CMOS technology framework. This will contribute to the growth of e-health services assisted by AI and will fortify the development of Internet of Things (IoT) applications in health & wellbeing and digital society. H2TRAIN not only facilitates digital technology but also involves the development of new 1DM and 2DM-based devices for sensing, energy harvesting and supercapacitor storage. These innovations serve to integrate sport and health activities into IoT applications, making them accessible as wearable technology. H2TRAIN combines mature CMOS technology products for health and sport sensing with embedded intelligence as
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Advanced Multidisciplinary Training in Molecular Bacteriology' (AMBER), addressing dissemination and exploitation.

assistant: **Impact**

The advancement in life sciences has created a growing number of disciplines that are required to elucidate the increasingly complicated biological questions. This has led to an unsurpassed level of knowledge, but it has also resulted in a continuous specialization in PhD trainings, which makes the students less prepared for complex present day biological questions. To provide a better comprehensive and multidisciplinary PhD training in microbiology, we have brought together 10 EU partners and we have setup the ITN programme Advanced Multidisciplinary Training in Molecular Bacteriology (AMBER). Within this international training programme, we will investigate an important and multifaceted bacterial problem; the intertwinement of central carbon metabolism and several main cellular processes. To tackle this intricate topic the consortium comprises specialists in key areas of microbial physiology, including cell division, cell wall synthesis, RNA processing, DNA replication, metabolic regulation, stress management, metal homeostasis, metabolomics, and secondary metabolite production. This enables us to apply an integrative research approach that is necessary to solve this complex and essential bacterial problem. Importantly, this multidisciplinary project provides a unique training environment for ambitious early-stage researchers (ESRs). As a model system we will use the bacterium Bacillus subtilis. This is the best known Gram-positive organism, and it is also widely used in the biotechnology industry. In fact, the AMBER consortium includes 3 active industrial partners that use B. subtilis for different commercial purposes; enzyme production, synthesis of lipopeptide (antibiotics) or as probiotics additive. The training programme will therefore ensure that the ESRs will g
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Automated synthesis methodology for reliable RF integrated circuits' (SYSTEMIC-RF) under Horizon 2020.

assistant: **Objectives**

Due to the constant need for connectivity, radio-frequency (RF) circuits will be of upmost importance in applications developed for the Internet of Things (IoT), the fifth-generation (5G) broadband technology and electronic health (eHealth) monitoring. However, the design of RF circuits in nanometric technologies for IoT/5G/eHealth applications is becoming extraordinarily difficult due to the high complexity and demanding performances of such circuits/systems. The need for high performance, low power, low voltage and low area circuits is immense and traditional design methodologies based on iterative, mostly manual, processes are unable to meet such challenges. Consequently, current EDA tools are getting out-of-date because they were developed to support that kind of traditional methodologies. Also, the short time-to-market demanded by nowadays IoT/5G/eHealth applications is creating a design gap, thus leading to a productivity decrease in the deployment of such IoT/5G/eHealth applications. In this framework, the focus of the SYSTEMIC-RF (Automated synthesis methodology for reliable RF integrated circuits) project is to develop a new design methodology that allows optimization-based synthesis approaches of RF circuits, where the circuit sizing and layout are treated in a complete and automated integrated fashion, in order to achieve fully optimal designs in much shorter times than traditional approaches. Moreover, the methodology will also take into account circuits' and systems' time-zero and time-dependent variability, and will be integrated in a state-of-the-art EDA tool in order to ease its usability. This EDA tool will definitely help RF designers to meet the very demanding specifications of IoT/5G/eHealth applications in a reasonable time.


**Keywords:** Radio-fr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Carbonized Briquette Production with Process Integration for Natural Gas saving in the Briquetting Process'.

assistant: **Concept**

Briquetting of wood processing residues (sawdust,shavings) by screw-extrusion is atechnically proven operation. The produced briquettes are of an excellent quality which makes them suitable for various applications. However, the financial viability of this technology should be further improved to make this briquetting concept ready for further dissemination within Europe and elsewhere. One of the main problems is the high drying costs of the raw material (at present natural gas is used for drying). The overall objective of the project is: 1. to exploit the opportunity for production of a first class quality charcoal, based on briquetted wood waste and other biomass residues (agricultural, forestry, arboricultural); 2. to save natural gas, and the associated cost, used for drying the raw material for briquetting. However, the specific targets should be developed during the exploratory phase. Conditions which will guide the decisions are: - continuous carbonization should be realized; - excellent char quality is required (carbon content, volatile matter content, strength, etc.) - a gas quality suitable for combustion in the wood waste drying system should be achieved.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Sustainable and Recyclable Polymeric Thermosets', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The concerns connected to petroleum-based origin of polymeric materials and the problems related to the accumulation of plastic waste in the environment need an urgent solution. One possible strategy to address this dramatic situation is the exploitation of bio-based resources as precursors for polymers. In particular, the valorization of agro-food wastes via extraction of polymeric precursors could be a winning strategy. Furthermore, the implementation of dynamicity in crosslinked polymeric materials with the introduction into the polymeric networks of labile noncovalent and dynamic bonds capable of undergoing reversible formation and cleavage, will give to the corresponding materials innovative recyclability properties.Within this frame, this project aims to face the complex challenge of the production of sustainable and recyclable polymeric thermosets. The proposed target can be reached by exploiting the peculiar properties of vitrimers, which allows a direct recyclability or reprocessability of the polymeric networks. On the other hand, the use of bio-based polymers holds great promises for the development of sustainable materials. Therefore, the integration of vitrimer properties with bio-based materials appears a great combination of choice to achieve the expected aim. For this reasons, SURE-Polymer has assembled an international team of researchers whose expertise spans green chemical synthesis, biopolymer functionalization, polymer photochemistry, vitrimer design and 3D-printing technology for object fabrication. The project will be run within the international and intersectoral consortium where different and complementary competences of the partners will be shared and exploited creating synergisms. The aim is within the objective of the MSCA-SE call, where tran