RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Revealing an active mechanism of horizontal gene transfer in fungi' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Current theory asserts that eukaryotic evolution is almost exclusively mediated through vertical transmission, from parent to offspring, and relegates horizontal gene transfer (HGT), the movement of genes between individuals, to an extraordinarily rare event. In recent years, mounting evidence from high-quality genome sequencing has forced the field to consider that HGT is likely a persistent occurrence in eukaryotic evolution. However, as no active mechanism for HGT is known in eukaryotes, the evolutionary origin of these genes remains almost entirely a mystery. A potential vector of HGT in eukaryotes are transposable elements (TEs), parasitic genetic sequences that can replicate independently of their host genome. Recently, I discovered a novel group of TEs that are common in filamentous fungi, which I named Starships. These elements are massive, reaching sizes over 500 kb, and carry an extreme diversity of genetic “cargo”, some with adaptive functions such as plant pathogenicity. Furthermore, evidence suggests that many Starships have undergone HGT among a diverse set of lineages. Thus, I propose that the Starships represent the first known mechanism of active HGT among eukaryotes. I will examine this role by developing a tractable model system in which to observe HGT under laboratory conditions. This will be done by investigating the basic biology of Starship transposition in a model fungus with the use of transposon assays that we have recently developed and used to prove that the Staships are mobile. We will use this knowledge to design and create “donor” strains which we can pair with any recipient strain of fungus to monitor for HGT. Lastly, we will determine if fungi utilize the movement of the Starships to adapt to their environment by assaying the impact of a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Tools to Carve out Conformal Field Theories' (TcCFT).

assistant: **Innovation**

Recently a number of research efforts have been dedicated to the conformal bootstrap. The basic principle is that conformal symmetry and quantum mechanics should suffice to fix uniquely the dynamics of Conformal Field Theories (CFTs), which lie at the fixed points of the renormalisation group flow. This has led to ground-breaking results, such as the unprecedented determination of scaling dimensions in non-trivial CFTs including the celebrated Ising model in 3d. Thus far these endeavours have focused only on the simplest examples of correlation functions with low-spin operators or to supersymmetric CFTs.The project aims at advancing the goals of the CFT bootstrap further, by developing a combination of theoretical and numerical tools to systematically apply the bootstrap to correlation functions of higher-spin operators. The long term goal of TcCFT is to apply these tools to carve out the space of non-supersymmetric CFTs. Its short term objectives of developing effective techniques to manage higher-spin operators are of interest also in a broader context, for such operators are ubiquitous in any CFT.This proposal combines my expertise on higher-spin methods with world leading experts in the bootstrap program, and a secondment which will allow me to refine my programming skills needed for the computational parts of the project. The outcomes of the project will be critical in achieving a greater understanding of the landscape of quantum field theories, and with it allow me to proceed to the next step of my career and obtain a tenure track position in Italy.


**Keywords:** Conformal Field Theory, Holography, AdS, CFT, String Theory
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Regional disparities in cause-specific mortality in Europe: the role of local context and national health policies' to be submitted under Horizon 2020.

assistant: **Abstract**

Current socio-epidemiologic theories often perceive mortality (health) inequalities as a given and largely ignore the fundamental questions concerning their origin. Furthermore, the majority of prior studies on international differences in mortality have focused on cross-country differences without taking into account substantial regional variation within national populations. REDIM goes beyond the state of the art through performing a large-scale systematic investigation of the reasons for persisting and emerging spatial disparities in mortality across European countries. The scientific output of the project is crucial for developing and coordinating health policies aimed at reducing geographical inequalities in mortality across and within European countries.The project intends to quantify the degree of convergence/divergence in cause-specific mortality that occurs between subnational entities in Europe, and to identify determinants of these changes. REDIM focuses on two specific research questions:1) How does the process of the general mortality decline diffuse across space, and what causes of death contribute most to this diffusion?2) To what extent do national borders determine health borders?REDIM will tackle these research questions through analysing cause-specific mortality patterns and trends at NUTS-3 and NUTS-2 levels across 19 European countries. Mortality indicators will be interpreted in conjunction with contextual variables capturing the effects of local context and national health policies.The proposed research agenda is highly relevant to the context of the integration process within the European Union which strives to enhance coordination of policies to promote more equal access to all benefits and assets in society including health. Apart from expected
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Common Interactive Objects' in the context of a Horizon 2020 call.

assistant: **Objectives**

In CIO, common interactive objects are developed and explored to extend human control over the technological environment by human beings, both individually and together. CIO leads to a coherent framework of user interfaces to be applied in interaction design. Common interactive objects will provide a useful frame for furthering human computer interaction (HCI) theory, development of interaction design methods and the underlying technical platforms. Common interactive objects will empower users to better understand and develop the technologies they use. When carried through, the project offers new ways for people to construct and configure human physical and virtual environments, together, over time and within communities. The main objectives of CIO are to1. develop the conception of common interactive objects in order to offer a new understanding of human-computer interaction, focusing on human control. 2. develop support for building user interfaces in a coherent and unified framework. 3. make common interactive objects that will empower users to better understand and develop the technologies they use. 4. carry out ground-breaking research regarding the technological basis of common interactive objects with focus on malleability, control and shareability over time.CIO is methodologically rooted in HCI. CIO’s research methods combine empirical, analytical, theoretical, and design approaches, all with focus on the relationship between common interactive objects and their human users. CIO presents the idea that common interactive objects may radically innovate our understanding of use and building user interfaces. The gains of CIO will be a coherent new, high-impact way of understanding and building HCI across physical and virtual structures, bringing control back to the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'An affordable tool to turn the space surrounding us into a creative experience'.

assistant: **Objectives**

14% of Internet users regularly upload and share videos in a mobile scenarios. Videos are increasingly used as a key media, thus changing the way we create and consume digital information for professional or entertainment purposes.c-Space benefit from this trend and deliver a low-cost solution to reconstruct 4D scenes (3D plus time) of indoor or outdoor events from casual real-world footage (e.g. captured by mobile phones) through Video Based Rendering (VBR) techniques.c-Space  exploits familiarity with Augmented Reality (AR) software for tablets/smartphones and on emerging micro-projection technologies to unleash users' inventiveness by letting them create 4D content in a completely new way, thus reconstructing 3D scenes of real scenes at different times (4D) (e.g. public concerts, sports events but also meetings, parties or simple outdoor spaces etc.), which can be used as the virtual stage" for ubiquitous media-sharing.In fact, in c-Space, the 4D scene becomes a spatio-temporally-sorted repository of the digital resources available in the area. Users can contribute to the content through a creative crowdsourcing approach in which new localised digital content (e.g. videos, images, 3D models etc.) is created, linked (logically, geographically, and visually), and shared within its surrounding space.By significantly shortening the 3D content creation pipeline, c-Space fills a gap not covered by any technology current in the market, thus yielding manifold savings (in terms of time & resources) in several creative industries (performing arts, advertising, cinema, video games, cultural tourism etc.).Non-technical issues will also be explored, i.e. 1) social acceptance or social communication mechanisms emerging from projecting information onto the surrounding space, and 2)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Spectroscopy and Geochemistry of chert. Reconstructing human mobility in the Pyrenees from the first Modern Humans to the last Pleistocene hunter-gatherers' (SPEGEOCHERT).

assistant: **Concept**

In Palaeolithic archaeology, steep mountain ranges have been perceived as geographical barriers, impeding human mobility from the territories that flank them on both sides. This is the case of the Pyrenean mountain chain, a key area for studying mobility and territoriality of prehistoric hunter-gatherers, especially during the last glaciation (c. 120.000  11.000 BP), due to its geographic location and harsh environmental conditions. The Pyrenees were until recently considered by archaeologists as a complete hindrance to human mobility and the only possibility, it was thought, was through the less abrupt extremes. However, in my earlier work I was able to suggest that humans may have crossed over the mountains by several alternative itineraries, proposing that the classic view is most probably wrong. These works were based on a new approach to the analysis of prehistoric chert tools using geochemical methods and it is in this context that the SPEGEOCHERT project aims to investigate.  The project will innovatively employ an array of interdisciplinary methods to explore the possible routeways humans followed through the Pyrenees to overcome the rough milieu. This pioneering approach will be based on portable, low-cost, non-destructive, fast and accurate techniques consisting on the use of reflectance spectroscopy combined with geochemistry and the application of multi-variate statistics and GIS to develop predictive modelling. Through the analysis of large series of materials directly at the museums, the SPEGEOCHERT project will create a novel data corpus with accurate information related to the geological chert sources exploited by Palaeolithic groups. The results obtained in this project will not only significantly broaden our knowledge on human adaptations to harsh ecol
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Silyl and stannylcupration of acetylenes' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

The aim of this project is to study some reactions of metallo- metallat of multiple bonds with a great synthetic interest.  The reaction of some acetylenes carrying a silyl or stannyl group with silyl or stannylcuprates will lead to systems containing two or even three metals on the double bond, which makes it a very inte- resting sinthon. From these compounds we will try to introduce different electrophiles selectively on every end of the double bond.  Finally we will apply Knochel's reaction to our substrate in order to obtein C + 1 chains from the original structures.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'ASSESSMENT OF HEARING IN THE ELDERLY: AGING AND DEGENERATION - INTEGRATION THROUGH IMMEDIATE INTERVENTION' (2007-2013) targeting Seventh Framework.

assistant: **Abstract**

Hearing loss is one of the most common chronic health conditions in the elderly population with important implications for patient quality of life. The diminished ability to hear and to communicate is frustrating in and of itself, but the strong association of hearing loss with depression and functional decline adds further to the burden on individuals who are hearing impaired.  Hearing loss can limit communications skills: not to hear means not to understand what is being said. Hence deafness does not produce compassion but do often produce a sense of irritation.  Despite the prevalence and burden of hearing loss, hearing impairment is largely underdiagnosed in older persons and undertreated. The reason for this is that one of the most conspicuous signs of a hearing loss is that it cannot be seen! Actually, this is the reason why deafness does not receive the necessary attention. Too often, the public and still too many health care professionals underestimate the dramatic effects of deafness. Novel strategies should be explored to make screening and early intervention a feasible part of routine care. Project AHEAD III has been specifically designed to:  - Provide evidence of the effects of hearing impairment in adults and particularly in the elderly  - Analyse costs associated with the implementation of integrated large scale programmes of hearing screening and intervention in the elderly  - Provide quality standards and minimum requirements for screening methods and related diagnostic techniques  - Develop guidelines and recommendations on how to implement successful screening programmes to be tuned to the local, social, and economical conditions of a country.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The Effect of On-Line Product Search on the Market Structure of Consumer Durables' (SEARCHSTRUC), addressing dissemination and exploitation.

assistant: **Impact**

We propose to study the working of markets when consumers do not want to search all available choice options and when sellers recommend products based on what ""similar consumers"" have bought in the past. We argue that the current practice of on-line selling offers significant potential for selection mechanisms or limitations of what the consumer is aware of, prior to purchase. To study this issue, we propose and estimate a demand model that includes a formal model of consumer information search. This model accounts for limited product search and information effects on choice. Our proposed demand model can be estimated from a combination of browsing histories and ordinal demand data. Because these data are available for a wide cross-section of durable goods, the method we develop will likely have broader application than the strict confines of the current empirical context. The goal of developing this demand model is (i) to measure the severity of selectivity in self-motivated or seller-directed information search and (ii) to subsequently evaluate the consequences of selection for consumer welfare, and for market structure (e.g., concentration and firm competition). For instance, most product recommendation systems used in on-line selling create a feedback, between past sales and current sales, because popular products get recommended more often than unpopular ones. This polarizes product popularity beyond what it already was. Clearly such effects hold relevance when evaluating competition and entry, because in a feedback market where the big get bigger and the small get smaller, firms potentially offering new and innovative products find it difficult to enter. In sum, our study consists of (i) the development of demand models under imperfect product search, and (ii) t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Importance of oxygen supply in intrauterine growth restricted (IUGR) pregnancies: correlation between in vivo and in vitro studies' (IUGR) under Fourth Framework.

assistant: **Objectives**

Objectives: The aim of this project is to study the role of oxygen in the pathogenesis of intrauterine growth restriction (IUGR), which represents one of the most important causes of perinatal morbidity and mortality.Brief description: Timing of delivery still represents the best therapy. Abnormal umbilical arterial Doppler identifies a major defect in fetoplacental perfusion and has been associated with fetal hypoxia. In pregnancies complicated by pre-eclampsia (PE) there is evidence that the placental production of the endothelium derived vasodilator nitric oxide (NO) is altered. However, biochemical and morphological findings in IUGR suggest that fetal hypoxia is due to a failure of oxygen transport through the placenta, with associated intervillous pO2 values higher than normal. Studies will be implemented for proposing models of fetal hypoxia. Comparisons will be made between in vivo 1. Indirect clinical studies of the placental circulation by Doppler waveform analysis of the umbilical and uterine arteries, and 2. direct studies of oxygen placental exchange by biochemical analysis of intervillous maternal and umbilical venous blood at the time of fetal blood sampling, and of uterine venous and umbilical venous blood at the time of cesarean section. The in vivo findings will then be associated, in the same pregnancies, to studies in vitro: 1. morphological studies of branching index of villi and vessels, proliferation patterns, expression of growth factor receptors and 2. functional studies of L-arginine transport and Na+/H+ exchange in order to establish whether there is a strong relationship between a specific placental abnormality and the clinical findings. Particular focus will be on the pathophysiology of fetal hypoxia to define whether only the fetus, the fetu