RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The role of dopamine d2 receptors in the rewarding properties mediated by drugs of abuse' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Research objectives and content Acute administration of drugs, such as cocaine, amphetamines and opioids, produces euphoria in humans and reward in animal models (1, 2). Repeated administration of these drugs with adequate doses, frequency, and chronicity produce significant adaptive changes in brain regions relevant to reinforcement. The dopamine D2 receptor (D2R) has been implicated in the reinforcing effects of several addictives substances and in the control of behavioural responses to opioids. The present research proposal is based on the investigation of the involvement of D2R, and particularly the long and short isoforms of this receptor in the mechanisms underlying drug addiction. As experimental approach, lines of mice with reduced (+/-) or absent (-/-) expression of D2R isoforms will be used to study these phenomena. This research is of particular importance not only for the understanding of the involvement of D2 receptors in drug addiction, but also for its potential contribution in elucidating the molecular mechanisms leading to it. Training content (objective, benefit and expected impact) This project implies the use of different approaches in molecular biology, genetics and in behavioural studies. The possibility of carrying on the project in an institute of outstanding quality such as the IGBMC constitutes a unique opportunity to broaden my knowlodge and skills in neurobiology. I consider that such training is fondamental for my research carreer. Links with industry / industrial relevance (22) This research might lead to the development of novel treatments as well as of preventive measures for drug addiction
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Alentejo Green Hydrogen Valley delivering integrated full-chain sustainable hydrogen ecosystem with technical, economic, social and environmental benefits and superior upscaling/replicability.' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

H2tALENT launches a flagship Hydrogen Valley in Alentejo-PT to consolidate the strong investment in place and boost the penetration of “green” hydrogen by deploying new initiatives across the entire value chain from local production to use including distribution for a range of applications in industry, mobility and buildings while also connecting with existing/planned infrastructures and initiatives. In the next 5 years are foreseen 2.1 GW electrolysers, 180 ktons/y of “green” H2, 2 B€ investments and 5000 jobs in Alentejo. Safe design and operation are ensured to deliver certified “green” hydrogen. H2tALENT produces >500 ton/y used by several off-takers in industry, mobility (public bus & truck) and building (municipal pool). The strategic position of the Sines Port is valorised as a key multi-modal hub for interconnection and import/export as well the industrial ecosystem surrounding it. Optimal energy system integration is ensured via technology assessment and impact modelling to contribute to the national energy transition strategy. H2tALENT generates investments around 20 M€. Digital Twinning and tools for optimal planning and operation are delivered to support upscaling and replication, while professional upskilling and public perception equip the workforce with the needed competences and deliver social benefits. H2tALENT builds a global network where lessons learned from existing valleys are gathered, cooperation with Brazil and Morocco fostered and replication promoted in 2 follower valleys in DE Saxony and UK Midlands. Roadmaps and concrete actions for upscaling and replication are defined for the Sines Port, Alentejo and Portugal. The consortium includes 29 partners from 7 countries covering the entire value chain including energy suppliers, DSO, technology ma
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'training to Complexity: muLtidisciplinary approaches to rural and mOuntain sustainable devElopment and conservation for innovative Doctoral Programmes' to be submitted under Horizon 2020.

assistant: **Abstract**

CLOE will be an interdisciplinary and inter-sectoral Doctoral Programme developed and coordinated by the University of Genoa, as sole beneficiary, in collaboration with a network of host academic and non-academic organisations. UNIGE will recruit 15 Early Stage Researchers (ESRs, no PhD and less than 4 years FTE research experience), respecting mobility rules of MSCA. CLOE training is focused on  multidisciplinary approaches to mountain and rural sustainable development and conservation starting from historical, environmental and legal perspectives. It will support top-tier ESRs working on 4 closely related topics: mountain areas and heritagisation processes (T1); mountain conservation, cultural landscapes and conflicts (T2); coming back to the mountains (T3); mountain areas and environmental risks (T4). The 15 ESRs will be enrolled in 11 doctoral courses involved in CLOE through 2 calls for applications: the first cohort of 7 ESRs will start on November 1, 2021, while the second of 8 ESRs on November 1, 2022. A rich and diversified range of training opportunities will allow to broaden the cross-sectoral and interdisciplinary skills of a new generation of early-stage researchers (ESRs) and provide a common ground for their future careers and for new research paths with important implications for sustainable development and environmental and cultural conservation. UniGE, the university of Liguria, with campuses in the major cities of the Region and one of the most important of Northern Italy, is particularly qualified to conduct CLOE due to the previous and on-going projects of the involved supervisors. The doctoral programme will make it possible to network existing doctoral schools that deal with subjects related to mountain areas from different perspectives, and will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Structural and mechanistic study of co-translationally interacting nascent chains' to be submitted under Horizon 2020.

assistant: **Abstract**

Almost all fundamental biological processes involve protein complexes and therefore, efficient folding and assembly of homo- and hetero-oligomers is critical for cellular functionality and integrity. Recent studies have shown that many protein complexes assemble co-translationally by one fully-synthesized subunit engaging another subunit that is still in nascent state (co-post assembly). An ongoing study in the Bukau lab now revealed that assembly can also occur by interaction of two partner nascent chains (co-co assembly). Co-co assembly is mostly employed for the formation of homo-oligomers and exists in all kingdoms of life.. Despite initial evidence of its existence, very little is known about the molecular mechanisms driving co-co assembly. This includes information on whether co-co assembly requires co-localization of two polysomes or can happen on one polysome.. Furthermore, it is currently unclear whether co-co interactions require preceding nascent chain folding steps and to what extent co-translationally acting chaperones coordinate the process and the impact of translation speed on co-co assembly.I propose to study mechanisms of co-co assembly using the dimeric chorismate mutase (PheA) as a representative top candidate from a high throughput screen for co-co assembling protein complexes in E. coli. Employing cryo-electron tomography, I will analyse the three dimensional arrangement of E. coli ribosomes in the context of a polysome to assess how organization of translational machinery allows co-co assembly. Moreover, I will study the co-translational cascade of folding steps of chorismate mutase by utilizing FRET on in vitro prepared nascent chains. Finally, I plan to explore the impact of co-translationally acting chaperones and translation kinetics on co-co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'AN APP TO HELP EUROPEAN COMPANIES TO RETAIN TALENT AND REDUCE JOB TURNOVER' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

To reach full productivity, a new employee typically takes from 8 to 12 months. Moreover, during his/her first 45 days, 20% of them decide to quit. Currently, approximately 75% of the companies worldwide have implemented an onboarding process investing an average of €5,380 per new hire. Manual delivering of onboarding information is not effective, but it is a heavy workload for HR managers and cannot be tracked; whereas available software in the market simply refer the employee to the intranet, which can consume up to 30% of the workday. MoB is an app dedicated to onboarding, with 22 modules delivering effective communication using: push-up notification, maps, surveys, virtual reality videos that allow the user to know the facilities and gamification, that increases the probability and an effective consumption of information. And which is more important, MoB is a non-intrusive, white-label and extremely intuitive app: it can be seamlessly integrated into companies’ existing IT systems, with perfect alignment with the corporate image, and easily configurable and manageable by non-IT experts.We have a SaaS business model that allows: 1) employees (end-users) to increase 23% their confidence and satisfaction and to have access to 5% more benefits. Moreover, MoB reduces 56.4% the time expended to achieve self efficiency and social integration. 2) companies with high employee turnover rates (customers) to increase 75% employees’ engagement, while reducing 31% employee turnover. With MoB, employees reach 97.7% productivity within the first 10 days. Through this project, we aim to boost Iphonedroid competitiveness by generating revenues of €23.5M by 2026 and increasing our workforce by at least 50%..
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Development of a force-feedback technology for SME manufacturers of medical equipment and simulation systems' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Traditional surgical training procedures include the use of live animals (which have limited relevance), human cadavers (which are limited in supply), live human patients (requiring experienced supervision, which is also limited in supply) and artificial organs (which have limited realism). Hence the speed and cost at which new surgeons can receive training form limiting factors to the supply of experienced practitioners. Surgical simulation techniques, and particularly the application of virtual reality (VR), are one potential solution to this problem. Indeed, such systems already exist, imported into the European market from the US and Pacific Rim Countries. Economic and social pressures on the market for the provision of health care are driving the continued use and further development of new Minimally Invasive Surgical (MIS) Procedures. The use of MIS has grown significantly in acceptance and has seen extension of its use to a large number of surgical and investigative procedures with some 300,000 carried out in 1996 (3). The proposed RTD is in response to the urgent industrial need, amongst the SME system and sub system manufacturers, represented by the Core Group of Proposers, to take advantage of recent developments in medical visualisation and precision actuator systems and provide a technological solution to the two main product limitations, retarding market take up.Specifically, the provision of: - Increased functionality within next generation hardware systems that provide, simulated tactile feedback of tissue deformation and the forces and torques generated at the end of the instrument' resulting from the simulated action, increasing the realism of the system. - More efficient software systems able to run on low cost computing platforms, reducing total syste
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Silicon-Chip Based Efficient and Scalable Quantum Processing and Production of Photons' in the context of a Seventh Framework call.

assistant: **Objectives**

The scheme of coherent photon conversion (CPC) promises to break with a single device the two main conceptual roadblocks of scalable photonic quantum information processing: the scalable creation of single photons and the implementation of a deterministic photon-photon interaction. This could bring the vision of efficient and scalable optical quantum computing within reach of current technology. Such a future working quantum computer would revolutionize many fields of science and technology.After the first successful demonstration of a process suitable for CPC, published last year, the challenge is to reach sufficiently high effective nonlinearities. Silicon photonics, offers several distinct advantages for enhancing the effective nonlinearity making this possible. Also, it utilizes highly mature CMOS-fabrication technology with excellent design flexibility.The core research objective of the proposal is pioneering the design, fabrication and utilization of efficient CPC-devices based on integrated micro-cavities on a silicon-chip. The outgoing hosts Profs. Gaeta and Lipson at Cornell University (USA) have a world-leading expertise in fabricating and using novel silicon integrated-optics devices. In combination with the outstanding expertise of the return host Prof. Zeilinger at the University of Vienna (Austria) in photon-based quantum computing, this is ideal for the success of this proposal.There will be extensive micro-fabrication training at the renowned Cornell Nanofabrication Facility (CNF). Moreover, the broad complementary training program allows the fellow to reach an advanced level of professional maturity, enhanced by many international collaborations. The EU will gain direct access to a frontier technology: the design and fabrication of integrated (quantum)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Make Rail The Hope for protecting Nature'.

assistant: **Innovation**

MARATHON aims at extracting the maximum productivity from the existing rail infrastructure for producing efficiency, reducing operating costs and attracting new traffic to rail.This represents a market requirement for producing efficiency, reducing operating costs and attracting new traffic to rail. In fact, due to its fragmentation, the railway system efficiency is created through harmonisation and standardisation of the operating rules generating uniformity in the EU Rail Freight space as far as allowed by the existing infrastructure. In pursuing this overall objective the fast implementation of technologies and business solutions capable of delivering operational and visible cost effective results, is a fundamental improvement.MARATHON project is scheduled to prove a business case by demonstrating the effectiveness of the introduction up to market uptake of longer and heavier trains on a selected high-volume Trans European freight corridor. This would be achieved taking into account that the upgrade of the maximum speed for freight trains on currently constrained line sections up to 100/120 km/h with old or new generation wagons secures better trains’ paths for improved service performance. In fact, the bundling of volumes combining conventional and intermodal traffic whenever applicable between large scale terminals/hubs/yards is expected to generate the critical mass to foster the industrialized production of advanced rail freight services. This would be supported by the ability to rejuvenate the system by adopting management, booking, trains priorities and emergency management tools.MARATHON would become an example for an extension to other part of the EU network contributing to create an agreed EU standard, facilitating the adoption of recognised Safety Rules and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Dispersal Effects on Food web functioning: Theory and Experimental Research based on freshwater plankton systems'.

assistant: **Objectives**

Metacommunity theory and its empirical tests have yielded novel insights into how ecological communities are structured at multiple spatial scales. However, much still remains to be understood regarding the spatial structure of food webs. On the other hand, a well-known effect of chained predator-prey interactions is the existence of trophic cascades, which have almost never been studied in a spatialized context. Recently, it has been shown (by the outgoing host group) that an intermediate level of dispersal among communities tends to buffer the effects of trophic cascades when top predators periodically colonize communities. In this context, the proposed two-year project aims at (i) building a comprehensive model capable of capturing the main effects of dispersal on ecosystem functioning and stability when trophic cascades are present, and (ii) conducting mesocosm experiments on freshwater plankton food webs to confirm theoretical results on the determinants of the buffering effect of dispersal. The model will be built in two phases, first as a purely deterministic description of spatial food webs, and extended in a second time to account for demographic stochasticity of the upper trophic levels. The model will be developed in collaboration with researchers from both host groups, and will span both years. Mesocosm experiments will be conducted in an already existing experimental setting, during the first year. This part of the project will be accomplished in the outgoing host group, in collaboration with researchers skilled in experimental biology and statistical analyses. The project will help the fellow acquire new skills, notably in experimental ecology and hone other proficiencies (writing, presentation, management,…). The project will also allow the fellow to esta
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Secure Architectures of Future Emerging Cryptography' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

SAFEcrypto will provide a new generation of practical, robust and physically secure post quantum cryptographic solutions that ensure long-term security for future ICT systems, services and applications. Novel public-key cryptographic schemes (digital signatures, authentication, public-key encryption, identity-based encryption) will be developed using lattice problems as the source of computational hardness. The project will involve algorithmic and design optimisations, and implementations of the lattice-based cryptographic schemes addressing the cost, energy consumption, performance and physical robustness needs of resource-constrained applications, such as mobile, battery-operated devices, and of real-time applications such as network security, satellite communications and cloud. Currently a significant threat to cryptographic applications is that the devices on which they are implemented on leak  information, which can be used to mount attacks to recover secret information. In SAFEcrypto the first analysis and development of physical-attack resistant methodologies for lattice-based cryptographic implementations will be undertaken.Effective models for the management, storage and distribution of the keys utilised in the proposed schemes (key sizes may be in the order of kilobytes or megabytes) will also be provided.This project will deliver proof-of-concept demonstrators of the novel lattice-based public-key cryptographic schemes for three practical real-word case studies with real-time performance and low power consumption requirements. In comparison to current state-of-the-art implementations of conventional public-key cryptosystems (RSA and Elliptic Curve Cryptography (ECC)), SAFEcrypto’s objective is to achieve a range of lattice-based architectures that provide com