RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Dynamic performance modelling and controller design of a mini-scale organic Rankine cycle unit for heavy duty vehicles' (DYNCON-ORC) targeting Horizon 2020.

assistant: **Abstract**

Internal combustion engines of heavy duty vehicles convert only approximately 40 % of the combustion heat to mechanical power, while rest of the heat is rejected into the environment as waste heat. An organic Rankine cycle unit that recovers part of this waste heat is expected to reduce the fuel consumption and carbon dioxide emissions by about 15 % of the heavy duty vehicle. However, the waste heat from internal combustion engines of heavy duty vehicles is characterized by large fluctuations in load, making it a challenging task to control an organic Rankine cycle unit in an efficient, safe and cost-effective manner. A few prototype of mini organic Rankine cycle units for truck applications have been tested, but no commercial products are available; the aforementioned control challenge being the major barrier for their commercialization. The primary objective of DYNCON-ORC is to develop an appropriate controller for a mini-scale organic Rankine cycle unit for waste heat recovery from internal combustion engines of heavy duty vehicles. Advanced numerical models of the organic Rankine cycle unit including its components will be developed for simulation of the steady state and dynamic operational conditions. Based on the results of the dynamic model, a non-linear model predictive controller will be designed and optimized. The numerical models will be experimentally validated and implemented on a real organic Rankine cycle system. Through the collaboration with international, world-leading partners from industry and academia it is ensured that the project will be successfully completed and that the findings of the project will be transferred to and implemented in industry. In broader terms, the project will contribute to the development of a more efficient energy system fo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Attosecond physics, free electron quantum optics, photon generation and radiation biology with the accelerator on a photonic chip' (AccelOnChip).

assistant: **Innovation**

Resting on our demonstration of laser-driven nanophotonics-based particle acceleration, we propose to build a miniature particle accelerator on a photonic chip, comprising high gradient acceleration and fully optical field-based electron control. The resulting electron beam has outstanding space-time properties: It is bunched on sub-femtosecond timescales, is nanometres wide and coherent. We aim at utilizing this new form of all-optical free electron control in a broad research program with five exciting objectives: (1) Build a 5 MeV accelerator on a photonic chip in a shoebox-sized vessel,(2) Perform ultrafast diffraction with attosecond and even zeptosecond electron pulses,(3) Generate photons on chip at various wavelengths (IR to x-ray), (4) Couple quantum-coherently electron wavepackets and light in multiple interaction zones, and(5) Conduct radiobiological experiments, akin to the new FLASH radiotherapy and Microbeam cell treat-ment.AccelOnChip will enable five science objectives potentially shifting the horizons of todays knowledge and capabilities around ultrafast electron imaging, photon generation, (quantum) electron-light coupling, and radiotherapy dramatically. Moreover, AccelOnChip promises to democratize accelerators: the accelerator on a chip will be based on inexpensive nanofabrication technology. We foresee that every university lab can have access to particle and light sources, today only accessible at large facilities. Last, AccelOnChip will take decisive steps towards an ultracompact electron beam radiation device to be put into the tip of a catheter, a potentially disruptive radiation therapy device facilitating new treatment forms. AccelOnChip is a cross-disciplinary high risk/high return project combining and benefiting nanophotonics, accelerator s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Neural networks'.

assistant: **Objectives**

The objective of this EuroConference series is to analyse and develop a new concept of Bacterial Neural Networks", with particular emphasis on "Inter- and Intracellular Signalling and Signal integration". An important underlying theme of these meetings is the development of new techniques to analyse gene expression and complex regulatory circuits in bacteria, with emphasis on the fact that this technology crosses the boundary of academic and industrial research.Consequently, an important objective is to encourage participants and invite speakers from both sectors. "Bacterial NeuraI Networks" implies that bacteria can to a degree "think" and can certainly learn and adapt to flourish in a particular environment. This could be achieved through the sensing and processing of enormous amounts of information which must then be integrated with many regulatory networks, including cell cycle controls, in order to maximise growth and survival in a given niche.These concepts bring together specialists involved in signal transtrariduction, chemotaxis and movement, differentiation and development, stress responses, pathogenicity in plants, mammals and insects, quorum sensing, mathematical approaches to complex processes, DNA-chip and micro-array technology and cell cycle regulation."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Advancing Bone Tissue Engineering: Biologically Active Bioinks for On-Demand Microvascularized Bone Biofabrication' in the context of a Horizon Europe call.

assistant: **Objectives**

Bone defects resulting from trauma, and pathological conditions compromise skeletal structure and function, leading to reduced mobility, diminished quality of life, and substantial global healthcare costs. Understanding and addressing these conditions requires reliable and sustainable 3D in vitro models of healthy and diseased bone tissue to advance knowledge of bone biology and develop new treatments; however, the inherent complexity of bone microcapillary architecture and biology has long hindered their development. To overcome this, MiVasBone project, proposes a pioneering bone-vascularized tissue-engineered platform that integrates advanced bioengineering strategies to replicate physiologically relevant bone environments. The approach combines microfluidics, 3D bioprinting, and multifunctional degradable hydrogel networks to generate vascularized bone models. A central innovation is the bioprinting of degradable osteoblast-laden liquid-core microcapsules, which serve as modular units forming microchannel networks replicating native vascular branching patterns, enhancing cellular viability, nutrient delivery, and tissue integration. By merging biomaterials science, biofabrication, and cell biology within a multidisciplinary framework, MiVasBone will provide transformative insights into bone-vascular biology, accelerate novel therapeutic development, and establish robust platforms for translational research, including drug testing and disease modeling. Leveraging world-class facilities at USFD and guided by Profs. Frederik Claeyssens and Gwendolen Reilly, and Dr. Mehdi Khanmohammadi, the project ensures expert training in material science, biofabrication and tissue engineering. This two-way knowledge transfer guarantees research excellence while advancing the Fellow’s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Art Academies in China: Global Histories and Institutional Practices' (CHINACADEMY).

assistant: **Innovation**

Art academies played an essential role in shaping modern art in China. They were the sites where European methods of art education were introduced; where the social role of the modern artist was defined; where the importance of traditional art forms and training methods was negotiated; where art history as a modern field was established; and where political and ideological changes in artistic practices were first implemented. Today, art academies incorporate laboratories of innovation as well as academic curricula inherited from the socialist period. Thus, they are emblematic of the dynamics within the Chinese cultural sphere and society at large, and of the tensions between a rapid globalization on the one hand and the preservation of cultural heritage and national identity discourses on the other.By studying art academies, their global histories and institutional practices, as the most significant actors in modern Chinese art, CHINACADEMY offers new understandings of the aesthetic, social, and political conditions of artistic creation in modern and contemporary China. Tracing the transnational connections to Japan, France, the Soviet Union, and other regions, it shows how institutional structures and artistic practices were adapted to the requirements of Chinese society in acts of cultural translation. It questions existing narratives of modernization, conservation, and political influence in art by highlighting personal affiliations, the agency of institutions, issues of conflict, and gendered experiences. These will be excavated through oral histories as well as archival records. By stressing the importance of academic and traditionalist practices, CHINACADEMY also decentres the paradigm of modernism that is still prevalent in global histories of modern art. It ther
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Syntax and semantics for intelligent knowledge acquisition and information handling formalisms with tractable applications to software design' (1994-1998).

assistant: **Innovation**

Recent research results in Theory of Actions, Database Updating, Belief Revision and Abduction employ stronger, more reasonable and constructive forms of Nonmonotonic Reasoning. However these results do not account for a plethora of basic features of an intelligent system or agent. We propose the study of these formalisms and their extensions by means of more conceptually satisfactory structures, such as metric spaces, and syntactical representations of them. We believe that this study will bring us closer to a description of an intelligent system by taking into account its global preferences. Our approach will b resource-conscious by studying its complexity and by logically characterising it with simple rules. Links with applications to Artificial Intelligence and Knowledge Engineering, such as Planning and Diagnosis, will be investigated.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Elucidating Dendritic Cell Heterogeneity and Functions in Metabolic Associated Fatty Liver Disease'.

assistant: **Objectives**

The increasing clinical and societal burden of metabolic-associated fatty liver disease (MAFLD) coupled with the current lack of therapies highlights the need for a better understanding of the mechanisms driving this disease. In recent years, studies, including my own, have identified that MAFLD is accompanied by a change in the T cell subsets present in the liver and blood. However, the functions and causes of these altered populations remain largely unknown. Conventional dendritic cells (cDCs) function to sample antigens in the periphery and subsequently migrate to the lymph nodes (LNs) where they induce the proliferation and polarisation of naïve T cells, which then home back to the periphery to perform their functions. As such, by manipulating cDC function, we could potentially alter the T cells present in MAFLD and hence improve disease outcome. To date, studies of cDC function in MAFLD have been hampered by our limited understanding of cDC heterogeneity and the lack of specific tools with which to manipulate them in vivo. Building on the cDC expertise of the host lab, the single cell technologies established to dissect heterogeneity, and access to more specific models to target these cells, here, I aim to dissect cDC heterogeneity in the fatty liver. To this end, I will combine the mouse models of the host lab, with my expertise working with human material to identify the conserved features across humans and mice. As MAFLD is associated with an increase in CD8+ T cells, I hypothesize that by manipulating the main cDC subset associated with cross-presentation of antigen to naïve CD8+ T cells, namely the cDC1s, I can manipulate disease progression. Using the novel XCR1-CRE mouse model to specifically target cDC1s in vivo, I will investigate the in vivo functions of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'ENERGY FOR A GREEN SOCIETY: FROM SUSTAINABLE HARVESTING TO SMART DISTRIBUTION.  EQUIPMENTS, MATERIALS, DESIGN SOLUTIONS AND THEIR APPLICATIONS' (ERG) targeting Seventh Framework.

assistant: **Abstract**

The ERG project focus on the solar energy supply chain, starting form photovoltaic cells (PV) and proceeding with energy extraction (harvesting) techniques, high efficiency power conversion and finally managing the energy distribution inside a smart grid, with the target of different classes of applications, from house to small area, as well as application specific “local grid” (healthcare, automotive, etc.). By considering  the full solar energy supply chain, we expect relevant improvements of the industrial state-of-the-art in the efficiency of PV cells, in the optimization of energy generated by PV systems, in the loss reduction of power converters and finally in energy management strategy. At the initial chain-link of the energy value chain, we primarily target the development of ultra-thin (50-20 micron) Si wafer PV cells, Si heterojunction cells, novel architectures (e.g. back-contact), novel materials (for Si heterojunctions, ARC, and dielectrics), novel approaches for screen printing and laser processing. As a promising low-cost alternative to Si we will pursue the goal of totally printable dye-sensitized-solar cells (DSSC) to demonstrate DSSC products for commercial applications. The next chain-link deals with optimization of the energy generated by PV systems by focusing on power management electronics for silicon cell panels and on micro electromechanical systems for Concentrated cells (CPV). The architecture study will elaborate different profiles of end-users, including direct grid connection, energy storage options and E-mobility support. At the end of the chain we will develop behavioural models for the individual components of the “Smart Grid” to allow for optimal energy dispatching and battery charging algorithms based on wireless sensors distributed ov
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'High-Q filter banks enabling unprecedented selective and high-sensitivity radiometers for environmental sensing' (TERAFILT) targeting Horizon 2020.

assistant: **Abstract**

This project proposes a new architecture of sub-terahertz (THz) radiometers, which, for the first time, allows to combine high frequency selectivity, high sensitivity and high compactness, intended to be used in Earth-observation environmental sensing applications.There exists two radiometer detector types: 1) direct-detectors have best-possible sensitivity, but poor frequency selectivity, even when equipped with superconductive filters which require bulky and energy-demanding cryogenic cooling systems; 2) heterodyne-receivers, which are compact and have excellent frequency selectivity, but have inherently inferior signal-to-noise ratio.The PI, in his ERC CoG, has developed a new terahertz technology enabled by silicon micromachining, and has demonstrated world-record breaking narrow-band filters at sub-THz frequencies (Q=800 at 450 GHz, 1600 at 150 GHz), which, even at room temperature, are superior in performance to state-of-the-art THz filters requiring cryogenic cooling. Furthermore, he has developed a micromachined waveguide switch technology with unprecedented on/off ratio (insertion loss of 0.6 dB, isolation of 50 dB at 220 GHz). These results will be combined for the first time to a new direct-detector based radiometer architecture, enabled by a proposed micromachined switched-filter bank. Such a compact and high-performance radiometer can even be utilized in CubeSat high-density weather-satellite constellations, which are predicted to replace current weather satellites and enable a weather update every 15 minutes as opposed to several hours, which is required for dynamic monitoring for instance the development of severe storms. A proof-of-concept demonstrator for measuring the 183 GHz water line, capable of resolving sub-spectral lines at highest-possible sensi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Tracking the Endocytic routes of growth factor receptor complexes and their modulatory role on signalling' (ENDOTRACK).

assistant: **Innovation**

Endocytic trafficking plays a more active role in the regulation of polypeptide growth factor (GF) signalling than recognizedbefore. Despite great progress in the description of the endocytic routes and their molecular regulation, we are far from acomplete understanding of the endocytic trafficking of GF receptor (GFR) complexes and to which extent their signallingactivity requires and is modulated by these routes. The EndoTrack project aims at filling this gap by gaining basicknowledge of the relationship between the endocytic transport and signalling activity of GFRs. EndoTrack combinesleading European interdisciplinary research teams to pursue the following aims:1. To define the trafficking routes of various GFR complexes in cultured cells with an unprecedented degree ofprecision, combining high-throughput microscopy, electrochemiluminescence technology and automated image analysis.2. To define the molecular machinery responsible for this transport, using proteomics and functional genomicsapproaches, and generate proof of concept that trafficking contributes to GF signalling activity in cultured cells.3. To integrate the information from cultured cells with in vivo studies on animal model systems, in particularDrosophila, zebrafish, Xenopus and mouse.4. To test the relevance of the modulation of endocytic trafficking on signal transduction in disease model systems.Within 4 years, the use of knockdown approaches, reporter cell lines and animals, combined with target validationproprietary technology from the biotech SMEs, will provide a new generation of assays to measure GFR traffickingand signalling. These assays will lead to novel key regulatory components, and therefore a new generation ofdiagnostic markers and potential targets for modulation of GF signalling and