RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Genetic factors Enabling Microbiome Symbioses: Bees as a natural model system' (2021-2027) under Horizon Europe.

assistant: **Objectives**

The gut microbiome is essential for the wellbeing of many animals including humans and bees. However, the genetic factors that enable stable, healthy microbiomes remain poorly understood. In particular, little is known about how different members of a gut microbial community communicate and interact with one another, both at the molecular level (which genes underlie the interactions) and the ecological level (how these genes are distributed across populations). Due to the complexity of most gut microbiomes, previous work in this field has largely been limited to in vitro studies using simplified, synthetic communities. In contrast, the core aim of this project is a systematic analysis of microbial interaction mechanisms at both the molecular and ecological levels. Unlike other systems, we can culture all members of the bee gut microbiome and have recently developed genetic tools for their manipulation. I will leverage these unique advantages, together with my expertise in social bees (honey bees, bumble bees) and microbial genetics, in an integrative approach to fulfil the project objectives. Work Package 1 will reveal the genes underlying pairwise intermicrobial interactions though unbiased in vitro and in vivo transcriptomics and proteomics. These genes, together with candidates I previously identified (secretion systems and toxin genes), will be investigated in detail using genetic and biochemical methods to uncover their mechanisms of action and novel functions. Work Package 2 will clarify how these interactions play out across populations by assessing variation of interaction genes with ecological factors (geography, host background), and by probing the evolutionary forces that lead to these variations. Our findings will contribute empirically to identifying the ge
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The modulation of sox transcription factors, an example : sox9' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The implication of the SOX in the development is increasing every day, but their specific functions, their partners, targets and the possible redundancy of function are still unknown. This project focuses on the study of SOX9 transcription complex, in order to obtain the more general rules about the SOX containing complex and about their functions
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Towards H2ydrogen Integrated eConomies In NOrthern Italy' to be submitted under Horizon Europe.

assistant: **Abstract**

TH2ICINO (Towards H2ydrogen Integrated eConomies In NOrthern Italy) supports the deployment of micro hydrogen economies for the EU by developing and demonstrating a full ecosystem integrated by 6 replicable use cases linked to the steps of the hydrogen value chain. The results will validate a Master Planning Tool (MPT), which replicability will be then tested. The demonstration of the hydrogen valley will work on the four pillars of the hydrogen value chain: (i) hydrogen production, (ii) hydrogen storage, (iii) hydrogen distribution, and (iv) hydrogen consumption and will send the initial status of TH2ICINO in order to enable replication and expansion. A first stage will include modelling, simulation and scenarization, from electrolysis plant to end-user in order to evaluate different scenarios and optimize them taking into consideration the technological constraints. Once the optimal cases are defined, an implementation phase will bring to real-life the innovative concept of the ecosystem tangible results to feed the MPT.


**Keywords:** Digital Planning tool, Hydrogen economy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'New approaches in the development of Hypoallergenic implant material in Orthopaedics: steps to personalised medicine' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Europe is confronted by a demographic challenge as a decreasing work force has to support an increasing elderly population. The economic risk implied by this burden could be addressed by efforts to achieve an increase in Healthy Life Years. One key element would be to ensure unrestricted mobility for especially the elderly, allowing them to stay at work for longer. Irreversible joint deterioration often requires a joint replacement. Implantation of artificial joints is one of the most successful orthopaedic interventions. However, an increasing number of patients receive revision surgery with these 10 % of these contract an infection and 50 % develop an adverse immune reaction (AIR) to conventional implant material. At the moment the reasons for the development of AIR are inadequately understood. Our proposal contains innovative solutions concerning this problem. A predictive approach using biomarkers will identify patients with risk to develop AIR. These patients will receive hypoallergenic endoprostheses, avoiding AIR to conventional material. Novel hypoallergenic material combinations will be developed in the frame of this consortium by material scientists and implant manufacturer. Via immunological, microbiological and biocompatibility testing the development and production process will be improved constantly. The matching of implant material with the allergenic background of patients will avoid complicated and cost-intensive reverse reactions and is a step towards personalised medicine. A further approach is to achieve a better understanding of mechanisms of AIR, and its faster and easier diagnosis using sensitive diagnostic biomarkers for an accurate differentiation from low-grade infection. Additionally, mathematical modelling of results from different methods wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'European Training Network on Sustainable Multi-functional Automated Resilient Transport Infrastructures.'.

assistant: **Concept**

Sustainable Multi-functional Automated Resilient Transport Infrastructures ETN, will bring together  a stimulating platform where the stakeholders of the transport infrastructure sector will work alongside world-wide experts in smartening of systems (developers of high-tech sensors, advanced monitoring equipment, automated structures, etc.,) with direct support from the roads, railways and airports managers. This environment will enable talented graduates to conceive the transport infrastructure network of the future and will provide them with world-wide extended training in each of the four pillars supporting the SMARTI vision: designed to last by maximising recycling and minimizing impact (Sustainable), conceived not for transport purposes only and towards optimisation of land use (Multi-functional), equipped for communicating with managers and users, to allow a more intuitive use and a simplified management (Automated), built to be adaptable to natural and anthropogenic hazards (Resilient). The consortium will combine and share expertise to offer advanced scientific training structured into network-wide thematic taught modules combined with original research supported by secondments that will expose fellows to both academia and industry and will also allow them with the possibility to be award with Doctoratus Europeus. The training programme will be enriched by specific modules to support job creation by enabling the fellows with business, entrepreneurship, communication, project management and other transferrable skills. A tailored Dissemination strategy will evaluate the variety of channels and means appropriate to allow the fellows to be prepared and successful in reaching both scientific and larger public audiences. As a result, SMARTI ETN will create a new gener
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Framing And Bridging Regional research and Innovation ecosystems Capacities for a renewed ERA' (2021-2027) under Horizon Europe.

assistant: **Objectives**

Overarching aim of the ERA_FABRIC project is to define, structure, populate and validate the “interconnected knowledge space” foreseen by the EU ERA Hubs initiative (COM 2020 628 final). Three distinct, and intertwined, dimensions, all of them relevant for policy making, are adopted as a structuring principle for the community to be built and cultivated during the project:1) ERA Hubs as Knowledge Ecosystems: fostering the dynamic interaction of R&D and innovation actors at regional and multiregional levels, taking into account the different knowledge and cultural contexts and the alignment of research foci and industrial needs;2) ERA Hubs as Multi Stakeholder Platforms: bringing together the representatives of the various involved interest groups in a seamless and uninterrupted discussion and deliberation on strategic priorities, actions and results evaluation;3) ERA Hubs as a Policy Co Creation Toolbox: a transformative set of measures and tools operating in a “middle ground” needing to be configured as a distinct space from both the EU and the MS/Regional levels, historically presided over by “ad hoc” sets of instruments (e.g. Framework Programmes for R&I, Structural and Investment Funds, Interregional and Cross Border Cooperation Programmes).It is the consortium’s vision and assumption that the 3 above dimensions should be presided over and made interoperable, in order for the ERA Hubs initiative to become path breaking and impactful at broad EU level.ERA_FABRIC is designed by leading European actors in the domain of regional development. The 11 partners represent 8 Member States and 1 Associated State. With the addition of the letters of interest gathered before the proposal presentation, almost half of EU27 territorial coverage has been reached.


**Keywords:** ERA
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Innovation Foresight for MEDA Partners in the European Research Area'.

assistant: **Objectives**

INNFORMED aims to support RTDI Policy development processes in Egypt, Jordan, Morocco and Tunisia by increasing the use of participative foresight approaches to the development of innovation systems in MEDA partner countries with a view to opening up the ERA to the Mediterranean region. The project builds upon existing foresight experiences in Malta, Tunisia, Morocco, Jordan and Egypt. It draws upopn MoCo in a strategic consultative capacity and links up with on-going INCO projects such as ESTIME. INNFO RMED will use Innovation Systems thinking and a foresight approach to develop a structured Euro-Med dialogue in research and innovation, to embed innovation systems thinking in the region, to deepen and strengthen MEDA capabilities in RTDI related policy process design and implementation and to develop success scenarios for turning current MEDA strengths and RTD investments into RTD opportunities. Phase I consultation with MoCo members will identify appropriate national experts and prioritize aspects of MEDA innovation systems suitable for development through foresight activities. Phase II will involve the design of pilot foresight programmes. These will be implemented in Phase III. This work involves the execution of background analyses and the develop ment of input scenarios to support 'success scenario workshops' in Egypt, Jordan, Tunisia and Morocco. Dissemination will take the form of reports on workshop outcomes and a manual to support the take-up of these techniques in the region. It will be carri ed out via a dedicated mailing list and a dissemination event that will provide the basis for further cooperation in the FP and the ERA.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Designing organic molecules as platforms for reversible charge-to-spin conversion with applications in chromophore optimisation and drug discovery' (RadicalProtON), addressing dissemination and exploitation.

assistant: **Impact**

Chemistry and Biology are governed by molecules and how they interact. Crucially, what glues a molecule together are chemical bonds, made from atoms pairing all their electrons. Although preferred, this is not the only option: in the comparatively rare cases where a molecule presents unpaired electrons, it acquires a fascinating new status that transforms its chemical and biological properties, best described by the acutely apt name of radical. Despite the extraordinary toolset found in radical-bearing molecules, the rather demanding methods to radical formation currently available mean that only very specific molecular architectures can withstand them, inadvertently limiting the scope of their applicability.The aim of this ERC project is to show that reversible diradical formation upon deprotonation is prevalent, and yet unexplored, in general donor-acceptor organic molecules and use this new knowledge to develop novel design criteria in light-emitting molecules and drug discovery.To achieve this unique aim, I will exploit a widespread structural pattern in a novel way, enabling a molecule to reversibly convert its charge and spin and become a diradical. I will first characterise how different molecular constituents (un)favour diradical formation on isolated molecules. I will then establish, for the first time, the role that diradicals play in defining the function of the numerous bioactive molecules sharing the proposed structural pattern.By exposing the overlooked diradical character in general families of deprotonated organic molecules, I will deliver transformative mechanistic understanding on i) the photo physical properties of fluorescent proteins and ii) the reactivity of small molecule drugs, particularly a new class of covalent inhibitors. The field of organic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The pandemic within: tackling brain vulnerability in COVID19 at high resolution: NEUROCOV' to be submitted under Horizon Europe.

assistant: **Abstract**

The COVID19 pandemic has shown our health care fragility vis a vis novel pathogens, with a global disruption on societal welfare. Despite the towering success of vaccine development, lack of preparedness on integrative clinical and molecular phenotyping has emerged with clarity and highlights the need to scale translational efforts for personalized prevention and therapy. Of particular concern are the long-term consequences of SARS-CoV-2 infection with high and rising prevalence of chronic manifestations referred to as Post-COVID. Among these the neurological and psychiatric complications stand out for frequency, lack of treatment and devastating impact of their effects at pandemic scale. Here, we tackle the cognitive and neurodegenerative complications of COVID-19, referred to as NeuroCOVID, as a ticking pandemic within the pandemic that requires an innovation leap across disciplines. We pursue a multi scalar approach that reaches from epidemiology and mechanistic interrogation of host/virus interplay at single cell resolution through predictive modelling all the way to validation of biomarkers and repurposed drugs. The aim is to anticipate and effectively manage personalized trajectories of NeuroCOVID vulnerability and their impact at population level. For this we leverage two leading national health registries and three clinical cohorts to characterize the phenotypic spectrum of NeuroCOVID, its risk factors and its socioeconomic burden at high definition. We pioneer innovative robotics to scale brain organoid modelling and combine it with single cell multiOMICs and AI analytics to dissect the principles of the individual host response and render experimentally actionable the authentic genetic backgrounds of differential SARS-CoV-2 sensitivity. Through a substantive e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'USER-CENTRIC MANAGEMENT OF SECURITY AND DEPENDABILITY IN CLOUDS OF CLOUDS' (SUPERCLOUD), addressing dissemination and exploitation.

assistant: **Impact**

Today, despite its unravelling business benefits, distributed cloud computing raises many security and dependability concerns. Root causes include increase in complexity and lack of interoperability between heterogeneous, often proprietary infrastructure technologies. SUPERCLOUD thus proposes new security and dependability infrastructure management paradigms that are : 1) user-centric, for self-service clouds-of-clouds where customers define their own protection requirements and avoid lock-ins; and 2) self-managed, for self-protecting clouds-of-clouds that reduce administration complexity through automation. SUPERCLOUD will reach the following objectives:-Self-Service Security: Implementation of a cloud architecture that gives users the flexibility to define their own protection requirements and instantiate policies accordingly.-Self-Managed Security: Development of an autonomic security management framework that operates seamlessly over compute, storage and network layers, and across provider domains to ensure compliance with security policies.-End-to-End Security: Proposition of trust models and security mechanisms that enable composition of services and trust statements across different administrative provider domains.-Resilience: Implementation of a resource management framework that composes provider-agnostic resources in a robust manner using primitives from diverse cloud providers. The SUPERCLOUD methodology will be validated by testbed integration for real-world use cases in the healthcare domain, ranging from deploying a distributed medical imaging platform to running a full laboratory information system. The consortium is industry-led with partners actively involved in promotion of open source cloud technologies and contributing to major standardization bodies
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Danish EU Presidency Event for the Mission Restore our Oceans and Waters' under Horizon Europe.

assistant: **Concept**

The Danish EU Presidency Event for the Mission Restore our Ocean and Waters aims to convene stakeholders from across Europe and sectors, spanning research, policy, funding, industry, and civil society, to share knowledge, exchange practical experiences, and inspire collaboration. The event will focus on the Mission’s core objectives, ecosystem restoration and protection, zero pollution, and the development of a sustainable, climate-resilient blue economy. This cross-sectoral dialogue is essential to unlocking integrated solutions and fostering a shared commitment to achieving the Mission’s goals. As a high-level platform, the event will support the deployment phase of the Mission by developing a Strategic Roadmap for the implementation and scaling of solutions that restore and protect both marine and freshwater ecosystems, while advancing the green transition in aquatic environments. It will serve as a knowledge transfer forum, facilitating the integration of results and insights into policy frameworks, by synthesising key actions, enabling conditions, and deployment pathways. Its outcomes will help align scientific expertise and local innovation with EU-level strategy and policy development.


**Keywords:** Mission Ocean, Presidency event, EU Presidency, Conference, Mission Ocean and Waters