RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Improvement of feeds and feeding efficiency for seabass in cage farms in the Mediterranean' to be submitted under Seventh Framework.

assistant: **Abstract**

In 2005 the total world production of sea bass reached 80,000 tons. The estimated amount of feed used to support this production was 150,000 tons valued at about € 100 million. Notwithstanding the increase in production, producer’s profit margins are squeezed by i) the increase in price of feed ingredients, and ii) the decline/instability of fish prices. Feed costs account for up to 60% of total production costs and inappropriate feeding management can therefore be detrimental to farmer's profits. Optimal feed management includes the use of well balanced feeds covering the species’ nutritional and energy requirements and cost efficient feeding regimes. The large variation amongst generally poor industrial feed conversion ratios (FCR) obtained in European sea bass farming is a clear indication of inappropriate feeding. This project is a joint effort between European aquaculture stakeholders targeting the accurate determination of the basic nutritional requirements of sea bass throughout the production cycle and best practices in feeding regimes and technology in order to achieve a significant reduction in production FCR values. Specifically, the optimum dietary protein and energy levels which are crucial parameters for effective feed formulation will be determined for European sea bass and evaluated on the farm using the latest demand feeding technology. These requirements will be studied in relation to the main influencing biotic and abiotic factors which are fish size, diet composition, feeding level and frequency, water temperature and oxygen levels. The cost efficient use of diets with formulations targeting the specific seasonal and developmental needs of the fish will effectively improve production FCR and have a significant economic benefit for aquaculturists. Opt
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Completing the revolution : Enhancing the reality, the principles, and the impact of economics' credibility revolution' (REALLYCREDIBLE).

assistant: **Concept**

Applied economists routinely evaluate the effect of economic policies. For instance, what is the effect of raising the minimum wage on employment? Angrist & Pischke (2010) argue that applied economics has recently experienced a ""credibility revolution'': by switching to transparent methods to evaluate policies, applied economists have increased the credibility of their findings, and the impact of their work.In the first part of this proposal, I show that the credibility revolution is not complete. Two-way fixed effects regression, a policy-evaluation method used in as many as 26% of the most-highly cited papers recently published in the American Economic Review, relies on the assumption that the policy's effect is constant, across units and over time. In most applications, this assumption is not credible. Therefore, I propose a series of new differences-in-differences estimators, that do not rely on this constant effect assumption, and that can be used in virtually all the applications where two-way fixed effects regressions have been used.In the second part of this proposal, I argue that the credibility revolution's focus on unbiased estimators may be hard to defend, as variance also matters. I explore two ways of trading-off bias and variance. The first amounts to combining an unbiased and a biased but potentially more efficient estimator of the same parameter. The second amounts to deriving the minimax estimator of the policy's effect, under the assumption that this effect cannot be larger than a (potentially large) constant B.Finally, the third part investigates the potential impact of the ``credibility revolution''. Specifically, I will run a randomized controlled trial to measure the effect of following an online course presenting policy evaluations, in two very
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Improved electrolyte systems for sofcs operating at low temperatures' to be submitted under Fourth Framework.

assistant: **Abstract**

Research objectives and content Solid Oxide Fuel Cells are considered to be the most promising power generation systems with respect to high efficiency, low pollution and high fuel flexibility. For their technological application it is crucial to reduce the fabrication cost, which is directly related to the lowering of the operating temperature (600-800rC). This requires the development of new materials for the electrolyte (Ce(Gd)O3 or thin YSZ films) and the cathode electrode (LaCoO3). Our aim is the development of YSZ/CGO electrolyte films, which can be processed and operate without the formation of microstructure defects. The incorporation of a thin Ce(Gd)O3 film between the YSZ and the cathode, proposed in this concept, is added to protect YSZ against interaction with the cathode (LaCoO3), in order to avoid performance degradation. Training content (objective, benefit and expected impact) Optimisation of the co-firing process of YSZ and CGO as epitaxial thin layers will give me the advantage of being able to apply to the techniques of microstructural characterisation, quantitative microanalyses and diffusion modelling. Links with industry / industrial relevance (22) The success of this work will contribute directly to the commercial attractiveness of low temperature SOFCs, which is receiving significant industrial interest. The host institute cooperates directly with KWU/Siemens and Daimler-Benz in the SOFC development field.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Doing Anonymization Practically, Privately, Effectively and Reusably""'.

assistant: **Concept**

There is currently a tug-of-war going on surrounding data releases. On one side, there are many strong reasons pulling to release data to other parties:  business factors, freedom of information rules, and scientific sharing agreements.  On the other side, concerns about individual privacy pull back, and seek to limit releases.  Privacy technologies such as differential privacy have been proposed to resolve this deadlock, and there has been much study of how to perform private data release of data in various forms.  The focus of such works has been largely on the data owner: what process should they apply to ensure that the released data preserves privacy whilst still capturing the input data distribution accurately. Almost no attention has been paid to the needs of the data user, who wants to make use of the released data within their existing suite of tools and data. The difficulty of making use of data releases is a major stumbling block for the widespread adoption of data privacy technologies.This proposal outlines a research plan that considers the whole data release process, from the data owner to the data user.  It lays out a set of principles for privacy tool design that highlight the requirements for interoperability, extensibility and scalability.  A number of research goals are identified, around topics of synthetic data generation, correlated data modeling, data utility enhancement, and the application of these to the case of trajectory data. The goal of the project is Doing Anonymization Practically, Privately, Effectively and Reusablely (DAPPER).""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Endothelial Cell Molecular and Metabolic Heterogeneity in Pulmonary Arterial Hypertension' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

BACKGROUND: Pulmonary arterial hypertension (PAH) is a devastating disease, characterized by a dramatic increase in pulmonary arterial pressure and an intense remodeling of small intrapulmonary arteries. With the exception of the lung replacement therapy, PAH remains an incurable disease with poor survival. Recent studies have shown that in PAH, rewiring of the metabolism of the lung endothelial cells (ECs) promotes vascular remodeling. However, these studies overlooked that lung ECs are exposed to diverse microenvironments in vivo (various hemodynamic forces and stimuli), which might result in their phenotypic and metabolic heterogeneity, though this has never been investigated. OBJECTIVES & EXPERIMENTAL APPROACH: In order to characterize, for the 1st time, the lung EC heterogeneity in PAH, identify EC subsets, and determine in an unbiased way the metabolic gene expression profiles of these EC subsets, I will use single-cell RNA-sequencing (scRNA-seq) on freshly isolated lung ECs from PAH patients and from an animal model of PH. As proof-of-concept, I will evaluate the effects of a new metabolic therapy on these EC subsets, in vivo, in comparison to a clinically-used, ameliorative but not curative, PAH therapy. This approach, already validated in the host lab, promises to lay the foundation of a new paradigm in PAH where lung ECs are phenotypically and metabolically heterogeneous. It will yield novel insights into PAH pathophysiology, identify specific EC subpopulations driving the vascular remodeling process as well as new potential metabolic targets.  CAREER DEVELOPMENT: Combining my expertise on PAH (PhD thesis) together with state-of-the-art frontline technology (scRNA-seq) and innovative science (EC metabolism) (within the host lab) in a multi-disciplinary project
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Theory and methods for evidence based perinatal health care and policy in cross-national studies' to be submitted under Seventh Framework.

assistant: **Abstract**

Improving the organisation of healthcare services is one way to contribute to better maternal and infant health. Over the past 10 years, my research at the Epidemiological Research Unit on Perinatal Health and Mother’s and Children’s Health, INSERM U953, has focused on assessing the impact of the organisation of care on the health of babies born very preterm (<32 weeks of gestational age) in France and other European countries and on the effects of the restructuring of obstetric and paediatric health services on access to care for pregnant women and newborns My aim for this fellowship is to strengthen my research capacities by integrating knowledge from the field of health services research.  This fellowship with the Department of Health Evidence and Policy at Mount Sinai Medical Center in New York City, co-chaired by my outgoing fellowship supervisor, Professor Annetine Gelijns, offers me the opportunity to work in close collaboration with scientists who have expertise in evidence-based evaluation of health care and policy.  My specific objectives are to (1) acquire knowledge about theory and methods in health services research (2) develop methods for the study of the comparative organisation of perinatal care (3) understand the organisation of health services research in the United States (4) develop a network of contacts with health services researchers. Expected outputs are two scientific publications, a validated protocol for the study of organisation of care and policy characteristics in neonatal and obstetrics units and materials for a workshop on health services research and a course at the doctoral level to be offered on my return to France. In the return phase, I plan to work actively with my research unit as well as other research units within the new Institu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Understanding evolutionary dynamics of chromosomal inversions in adaption: the interplay of gene flux and selection' in the context of a Horizon Europe call.

assistant: **Objectives**

Understanding the genetic mechanisms that generate and preserve diversity is a central goal in biology. Chromosomal inversions, segments of a chromosome that are reversed in order, play a key role in the formation of locally adapted forms across a broad range of different species. They suppress recombination in heterozygotes, thereby maintaining large genomic blocks consisting of sets of locally adaptive alleles that can further diverge and evolve independently. Yet, exchange (‘gene flux’) between alternative arrangements can occur. It may be crucial for maintaining inversion polymorphisms and facilitating adaptation by reducing mutational load and generating novel allele combinations. However, the frequency of gene flux events, how they interact with selection, and their overall consequences for evolutionary dynamics and adaptation are still poorly understood. This project will investigate the frequency of gene flux events and their interplay with selection in a model system for adaptation, the threespine stickleback. In this ancestrally marine species, freshwater forms have independently evolved multiple times over very short timescales, despite ongoing gene flow from marine populations. Three ancient chromosomal inversions appear to play key roles in this process. However, in some freshwater systems, such as large lakes, the marine inversions persist, raising questions about their adaptive value in these environments. This project will use an ambitious multi-scale approach, from studying gene flux events in a single meiosis to large-scale global patterns to uncover the evolutionary dynamics of these special genomic regions and more generally advance our knowledge of the genetic architecture of adaptation.


**Keywords:** Evolutionary genetics, Chromosomal inversion,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Affective Control of Decision Making' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The environment is an ever changing system to which an animal has to properly respond in order to survive. Decisions are made in unfamiliar situations, where risk assessment critically impacts the decision making; or based on previous experience, where the animal has prior knowledge of possible outcomes. Decision making is a complex process that requires the interplay of multiple neural structures and constant re-evaluation of the outcomes that involve emotional factors. The brain structure most linked to emotion and affective behaviour is the amygdala and its aberrant function caused by lesions or neurodegenerative diseases is associated with impaired decision-making.The proposed research aims to understand the affective aspects of circuit mechanisms underlying decision making. Specifically, the role of an understudied pathway, the amygdalostriatal projection (basal amygdala, BA to dorsomedial striatum, DMS), in decision making; and the synaptic mechanisms underlying the interaction of this input with the well-known corticostriatal pathway (prelimbic cortex, PrL to DMS). Thus, a first goal aims to reveal the function of the BA inputs to DMS in an approach-avoidance conflict and to assess the association of neural activity with decision making behaviour. The second goal aims to uncover circuit mechanisms underlying the control of DMS neuron spiking by the amygdalostriatal pathway and how the cortical and amygdalar inputs impact each other in controlling the DMS activity.These experiments will reveal the role of BA projection in decision-making at DMS level and how the PrL and BA inputs affect neuron activity at single cell level, results that can elucidate the role of the convergent amygdalostriatal and corticostriatal pathways in control of DMS function. Our findings w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The Origins of Human Rhythm' (TOHR) under Horizon Europe.

assistant: **Objectives**

Humans are particularly rhythmic animals. Why did the human sense of rhythm develop? Many hypotheses try to explain the origins of our acoustic rhythm capacities, but few are empirically tested, compared, and comparatively investigated. This project searches for the evolutionary roots of human rhythmicity, breaking new ground through three concerted approaches. First, I zoom in on key rhythmic properties: isochrony, an even occurrence of events in time, and meter, a relative accentuation of events. Second, I compare hypotheses on rhythm origins, selecting the most relevant ones to music and speech and testing them against each other. Third, I target rhythm precursors in other species as predicted by these alternative hypotheses. I test four hypotheses, which propose that 1) gait or 2) breathing control, and the ability to 3) learn new sounds or 4) sing in a chorus are evolutionary precursors to human rhythm. I will use different measures including behavior, electrophysiology, gait tracking, breathing, and computational modeling to test whether the four features above predict rhythmic capacities. Comparative animal work is needed to test whether similar evolutionary pressures lead to similar rhythmic traits. I will collect data from humans and four more species. I will test seals, displaying vocal learning, and porpoises; both mammals have developed breathing control. I will also test siamangs, displaying rhythmic locomotion, and indris; both primates naturally sing in choruses, a rare trait in non-human mammals. Finding rhythm in other species will provide a test bench to reconstruct the origins of human rhythm. Resting on my background in bioacoustics and mathematics, the project expands in new challenging directions, such as neurophysiology of marine mammals, automate
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Towards river restoration conviviality' (REvive).

assistant: **Concept**

Nature and river restoration are high on the political agendas; the EU Biodiversity Strategy and Nature Restoration Law stipulate ambitious goals. However, in practice, river restoration projects – including barrier removal, implementation of ecological baseflows, and others – are contested. Different human and nonhuman actors have diverging ideas about what the future of rivers should look like. Underlying are multiple ontologies about what rivers are, can and should be; and epistemologies that define how rivers can be known. Through innovatively analysing river restoration as a political and contentious encounter of multiple ontologies and epistemologies, this project goes beyond the state-of-the art. Based on the study of restoration initiatives in three rivers in Spain, the project will generate new interdisciplinary knowledge about the complexities of river restoration. Rigorous and critical academic analysis will be combined with the exploration of pathways for constructive engagement: with local actors, the project will organize restoration design labs to develop methodologies for co-designing just and robust river conviviality. The project goes beyond mainstream formats of multi-stakeholder platforms through a focus on the ‘politics of design’ and ‘design justice’ that includes humans and nonhumans alike. This is a highly ambitious undertaking, which is made feasible through a careful methodological and conceptual set-up. The placement at the University of Girona and the secondment at the University of Twente will allow the researcher to develop a wide range of knowledges and professional skills; while she will use the project results and her expertise to stimulate transdisciplinary and critical debate in academia and practice. The non-academic placement with th