RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Functional Nanostar Encapsulated Nanocapsule for Cell-based High-throughput Drug Screening' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Chemotherapy has been the leading therapy for treating cancer to date. However, its applicability has been limited by high price and low effectiveness of current chemotherapeutics. The limitations could be overcome by understanding the therapeutic mechanism of drug candidates allowing the best compounds to undergo expensive and time-consuming clinical trials. Although cell-based profiling methods greatly streamline the drug screening process, the current methods are restricted by multistep processing, time consuming and low-throughput analysis, and the requirement of large number of cells. The FunStar Capsule proposal aims to develop a simple and powerful supramolecular nanocapsule platform for phenotyping drug-treated cell surfaces. This radically new concept in drug screening will generate characteristic spectroscopic patterns for different drug-treated cell surfaces that will be used to predict the mechanisms of new therapeutic molecules. The proposal introduces for the first time live cell Raman micro-spectroscopy for creating the patterns using a unique nanocapsule that is fabricated through the hierarchical assembly of functionalized gold nanoparticles (AuNPs) and nanostars. The AuNPs will recognize the cell membrane while the nanostars will create characteristic Raman signatures through a surface enhanced Raman scattering mechanism. The robust and biocompatible platform would provide several advantages: (i) rapid (minutes) analysis, (ii) less number of cells required (possibly single cell), (iii) label-free method, (iv) highly sensitive and non-destructive technique, (v) both efficacy and mechanism of a molecule can be determined from a single well of a microplate. This multidisciplinary proposal combines concepts of materials chemistry and life sciences to desig
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'u-Space sePAraTIOn management'.

assistant: **Concept**

SPATIO (u-Space sePAraTIOn management) will research the U-space services addressing separation between UAVs, in particular, strategic and tactical conflict resolution services and the relationship between separation and capacity in U-space airspaces. i.e., the relation with the Dynamic Capacity Management service.


**Keywords:** U-space, UAVs, separation, Tactical Conflict Resolution, Dynamic Capacity Management, Strategic Conflict Resolution
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Fake news detection in social networks using geometric deep learning' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

In the past decade, social media have become one of the main sources of news for people around the world. Yet, it comes with the danger of exposure to intentionally false information. The extensive spread of fake news has recently become a centerpiece of controversy following the highly debated elections of President Donald Trump and the Brexit vote. It is alleged that the outcome of these votes resulted from the public opinion manipulation by a massive injection of fake news, possibly sponsored by hostile foreign governments, constituting perhaps one of the most serious and unprecedented threats to the modern democracies. The ambition of GoodNews is to build the technological capability for algorithmic fake news detection in social media using a novel paradigm. Instead of following the traditional approach of analyzing the news content, we will analyze the news spreading patterns in social networks. The algorithmic core of GoodNews is based on a novel class of geometric deep learning algorithms developed in the ERC project LEMAN (Learning on Manifolds and Graphs). Our research group was among the first in the world to propose, implement, and patent generalizations of popular convolutional neural network architectures to graph-structured data such as social networks, allowing to do deep learning on graphs. The ability to learn fake news spread patterns on social networks will provide the needed breakthrough in the task of automated fake news detection. GoodNews will convert the geometric deep learning technology into a commercial application of fake news detection in social media. The focus of the project will be three-fold: developing a demo system for fake news detection with real data from social media; verifying and solidifying our IP portfolio and its licensing ter
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Autonomous Robot for an Automatic Inspection of Nozzle Welds in Nuclear Environment' (NOZZLEINSPECT), addressing dissemination and exploitation.

assistant: **Impact**

Regular in-service inspection is important to verify the integrity of welded nozzle sections in nuclear and other safety critical facilities. Nozzle sections made from austenitic steel can be susceptible to rapid crack growth due to thermal fatigue and stress corrosion. Early detection of cracks is therefore essential to ensure the continued safe operation of the facility in question.  In order to reduce the time and cost of such inspections there is an urgent need to develop a system capable of performing a full inspection of nozzles without the need to change probes. The aim of NozzleInspect project is to design an autonomous robot system that able to: reduce the inspection times, Improve defect delectability and sizing, Reduce human intervention which will reduce workforce radiation uptake and Reduce requirement for robotic manipulation and consequently reduce size and cost of robotic deployment system.  The goal of NozzleInspect project is to improve the reliability of the inspection of the welded nozzle sections in nuclear and other safety critical facilities. The robot will carry out a new and novel flexible phased array probe to allow a full inspection of nozzle weld areas and an advanced navigation system that follow the weld in nozzle. The presence of defects in these parts could lead to catastrophic component failure.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Collaborative Recommendations and Adaptive Control for Personalised Energy Saving' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Achieving the European environmental objectives for 2020 requires not only technological progress, but also a major change in energy consumption behaviour. The enCOMPASS project will implement and validate an integrated socio-technical approach to behavioural change for energy saving, by developing innovative user-friendly digital tools to make energy consumption data available and understandable for different stakeholders (residents, visitors, public actors, building managers, utilities and ICT-providers) in ways that empower them to achieve energy savings and manage their needs in energy efficient, cost-effective and comfortable ways. It will demonstrate how this can be achieved with a holistic approach that integrates visualisation of energy data collected from smart sensors, user-generated information and context-aware collaborative recommendations for energy saving, intelligent control and adaptive gamified incentives.  The enCOMPASS system will be realized as an open platform combining 1) context-dependent energy usage information from in-home sensors (smart meters and smart home appliances for heat and electricity), 2) user-generated information (automatic and manual activity tracking), 3) adaptive gamified energy visualisation and 4) intelligent controls and automation. The platform is developed to achieve sustainable changes in user energy consumption patterns without compromising comfort levels. The enCOMPASS system will integrate existing technology, product and service offerings of the utility and technology partners, customize and extend them to offer improved and new types of their offerings.The enCOMPASS platform is the heart of a new business ecosystem that enables players in the energy domain to develop their own white-label solutions on top of the plat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Cooperation between EU and Canada in Education, Training and Knowledge Management on Super-Critical Water Reactors' in the context of a Seventh Framework call.

assistant: **Objectives**

Nuclear power in general requires highly qualified, skilled and well trained professionals in order to assure the supply of energy and to secure safe operation and the development of reliable technology. The recent Fukushima nuclear accident in March 2011 firmly underscores such requirements.At the same time, the IAEA and OECD/NEA has observed a shortage of high level graduates educated in the nuclear field, combined with the retirement of professionals in the nuclear sector. For this reason, the EU Council issued conclusions and recommendations in the field of ‘needs for skills in the nuclear field’ in December 2008.Currently, the EU and Canada work on the Super-Critical Water-cooled Reactor (SCWR), a reactor concept selected by the Generation-IV International Forum because of the advantages regarding safety and sustainability.The EURECA! project, being a collaboration between the EU and Canada, will define an international education & training program which (i) enhances the skills of current professionals in the nuclear sector, (ii) attracts young graduates and professionals in other sectors to work in the nuclear field and (iii) enhances the mobility of professionals in the EU and Canada.The project focuses on the innovative SCWR concept due to its attractiveness to graduates and young professionals and to pave the way for future collaboration between the EU and Canada on this reactor type. Although the SCWR is still a conceptual reactor, the level of knowledge and skills regarding current, water-cooled reactors will be improved and ensured as well, since the concepts and technology of the SCWR are close to the ones of conventional water-cooled nuclear plants.The EURECA! project consists of a European organizational branch (consisting of EU participants), and a mirro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Mechanism of Holliday junction dissolution by the Bloom’s Syndrome complex' (BLMCOMPLEX) targeting Seventh Framework.

assistant: **Abstract**

Our genetic material is continually subjected to damage and efficient repair is needed for cancer avoidance. DNA double-strand breaks  are cytotoxic and are repaired either by Non Homologous End-Joining or Homologous Recombination (HR). HR provides an important function in DNA repair, where it serves the dual purpose of mending broken chromosomes and recovering sequence information that might be lost at sites of DNA breaks. The recombination process is initiated by exchange of strands between two homologous DNA duplexes (in mitotic cells, recombination generally occurs between two sister chromatids) and the resulting joint molecules can mature into four-way structures known as Holliday junctions. Similar DNA intermediates can be generated during DNA replication via regression of stalled replication forks, which may create a requirement for HJ resolution/dissolution during replication. The primary mechanism of HJ processing involves the BTRR complex which ‘dissolves’ HJs to form non-crossovers, a reaction that is critical to avoid loss of heterozygosity and tumourigenesis. HJs that persist to the late stages of the cell cycle are resolved by the structure-specific endonucleases MUS81-EME1, SLX1-SLX4 or GEN1. Our goal is to address the mechanism of action of the BTRR complex during dHJ dissolution. Understanding this process will further our knowledge of the cancer predisposition disease Bloom’s Syndrome, and will expand our understanding of the relationships between defects in recombinational repair and tumourigenesis.To gain insight into the mechanism of HJ processing by the BTRR complex we will:1.   Determine the molecular mechanism of HJ dissolution using structural and biochemical approaches.2. Define the interaction surfaces between components of the BTRR complex an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Unravelling the molecular-genetic underpinnings of hybrid defects in agricultural pests'.

assistant: **Innovation**

Mating with an incompatible partner can result in dysfunctional hybrid offspring. Multiple processes cause such hybrid defects, including incompatible gene interactions and cytoplasmic incompatibilities that are mediated by bacterial parasites such as Wolbachia. Hybrid defects are strong reproductive barriers that drive speciation and are being harnessed by new pest control strategies to suppress harmful pest populations. Although pivotal to our understanding of these biological phenomena and applications, the molecular-genetic mechanisms that underpin these incompatibilities remain poorly understood. With HYBRIPEST, we will unravel all major mechanisms, and their interactions, that shape hybrid dysfunction within a system that recently became amenable to such a research endeavour. The system of Tetranychus mite species (important agricultural pests) is typified by various processes that culminate in different hybrid defects and benefits from a recently developed genetic toolkit. For the first time, we will dissect the molecular-genetic underpinnings of cytoplasmic incompatibility from the perspective of Wolbachia and host, an approach that will test biological theory and identify novel pest control opportunities. We will identify the molecular-genetic bases of incompatible gene interactions within and between species, shedding light on early speciation mechanisms. We will test for mechanistic convergence of different incompatibility loci and study how polygenic hybrid dysfunction is controlled. We will implement high-resolution genetic mapping techniques and comparative genomics to identify (in)compatibility loci. The functional importance of (in)compatibility loci to hybrid dysfunction will be further validated by recombinant expression, genome engineering, and other
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Mobile and wireless communications Enablers for Twenty-twenty (2020) Information Society-II' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Key objectives of METIS-II are to develop the overall 5G radio access network design and to provide the technical enablers needed for an efficient integration and use of the various 5G technologies and components currently developed. The innovation pillars that will allow METIS-II to achieve this goal are • a holistic spectrum management architecture addressing the spectrum crunch, • an air interface harmonisation framework enabling an efficient integration of new and legacy air interfaces, • an agile Resource Management (RM) framework providing the dynamics required to efficiently adapt the integrated 5G air interfaces and radio concepts to the varying traffic demand and service requirements,  • a cross-layer and cross-air-interface system access and mobility framework ensuring an ubiquitous access continuum,• and a common control and user plane framework providing the means for an efficient support of the broad versatility of services expected for 5G as well as a future-proof and cost-efficient implementation of the 5G integration.On the strategic level, METIS-II will provide the 5G collaboration framework within 5G-PPP for a common evaluation of 5G radio access network concepts and prepare concerted action towards regulatory and standardisation bodies. Based on its very strong and international consortium with partners from all regions with strong 5G R&D initiatives (EU, US, China, Japan, Korea) with most of the major international vendors, major operators, and key researchers, METIS-II will have the unique capability to drive consensus building globally, to consolidate a full picture of the needs of mobile as well as vertical industries, and to disseminate the results towards the relevant bodies, forums, and standardisation groups in all regions.The METIS-II proposa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Improved pollution monitoring & control through the development of an innovative integrated multi-component continuous on-line analyser' (1998-2002), addressing dissemination and exploitation.

assistant: **Impact**

Scientific objectives and approach:The initial work will focus on the development of the TSAO laboratory research reactor to be used in the subsequent development of the analytical technologies for the individual contaminant species. Analysis will be based on the proven TOC analysis with innovative colour chemistry for nitrogen, phosphorus and metal ions. The reactor will incorporate the necessary flexibility to enable the different reagents and colour indicators to be introduced.Spectroscopic studies for the oxides of each element will be carried out with the aim of using diode arrays to measure the oxide concentrations. This will enable the prototype optical bench to be incorporated into the reactor system while minimising interference effects and eliminating the potential for contamination of the developed optical system.Sub-system designs for optical diode arrays and emitters, pumps, mass flow controllers, ozone generators, control and display software will be integrated into the multi-component pollution analyser for continuous on-line industrial use. This will be validated at a range of end user sites and the technology transferred to all partners in preparation for exploitation.Problems to be solved:The aim of the project is to develop an innovative analytical technology involving a patented two-stage advanced oxidation (TSAO) process that ensures complete reaction and hence measurement of a whole un-filtered sample. This unique oxidation technique has the potential to continuously operate on-line, and in real dirty" effluent. Feasibility studies have demonstrated this can be expanded from the measurement of organic carbon pollution and be applicable to the monitoring of total nitrogen, phosphorus, and heavy metals, e.g. aluminium and copper. However, this potent
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Postgraduate Research on Photonics as an Enabling Technology' (PROPHET).

assistant: **Concept**

Photonics is an important enabling technology for a wide range of applications in diverse areas. The photonics industry in Europe accounted for revenues of €49 billion in 2006, and is expected to soon exceed that of microelectronics. In the training network proposed here, a cohort of 14 early stage researchers and 5 young experienced researchers will be trained in the full gamut of skills required for a career in photonics, including materials growth, device fabrication, characterisation, design, theory, and commercialisation. A carefully-chosen, well-balanced consortium of 9 academic partners, 4 full industry partners and 2 associated partners are well placed to provide the training in these skills, with European and worldwide reputations as leaders in each field. These skills will be applied in four application areas; mode-locked lasers for Communications applications, solar cells for Energy applications, gas sensing for Environment applications, and fast tunable laser sources for OCT in Life Science applications. Each researcher will experience both academic and commercial environments thanks to the strong industrial involvement, resulting in multi-skilled, industry-focused graduates. PROPHET thus directly addresses the need for additional skilled photonics professionals, as identified by the European Technology Platform, Photonics21.