RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Earthquake prediction research in a natural laboratory-two' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

Earthquake Prediction Research in a Natural Laboratory - Two, is a two - year multidisciplinary project with the main objective to provide knowledge about earthquakes and related earth processes which can be a basis for reducing earthquake risk. This project is proposed in order to respond to the increasing requests from society, engineers, city planners and rescue teams for improved knowledge on where a destructive earthquake is likely to take place, how large it will be and when it is likely to occur. None of these requests are easy to fulfill. Making use of all relevant information about earth processes may bring us closer to solutions. It is significant to understand better the physical processes leading to earthquakes, and for that multidisciplinary approach is necessary. To analyze and monitor the physical processes involved, we take advantage of state-of-the-art technology and monitoring systems available in Iceland and of the involvement of scientists from 7 European countries which have carried out pioneering work in the fields of seismology, deformation, geophysics and geology. The project is a continuation of the PRENLAB project (ENV4-CT96-0252) which ends in February 1998. This is a new project using results from PRENLAB as a basis. The project also takes advantage of the SIL earthquake prediction project of the Nordic countries (1988-1995) when the basic seismic acquisition and evaluation system was created. The Mid-Atlantic plate boundary in Iceland is the test area for the project. It is composed of rift zones and transform zones. The well-exposed faults and fissures in Iceland can reveal the tectonic forces generating the earthquakes through a long period of time. Techniques have been developed to map active faults at depth and trace their motions by stu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Unfolded protein response in mammals' (UPRM) targeting Sixth Framework.

assistant: **Abstract**

The eukaryotic unfolded protein response (UPR) is an integrated cellular stress response that detects incorrectly folded proteins at the endoplasmic reticulum and acts to minimize their accumulation. The proteasomal degradation of misfolded proteins by ER associated degradation (ERAD) is a central component of the response, involving ubiquitin-conjugating enzymes (Ubc's) and ubiquitin-protein ligases (E3's) that are specifically active at the ER membrane. Ubc6e is a novel ubiquitin-con jugating enzyme that lacks a homologue in yeast and is involved in ERAD of higher eukaryotes. It would be expected to have a role in minimizing the accumulation of misfolded proteins at the ER but its expression, regulation and involvement in degenerative diseases have not been well characterized. Our preliminary studies indicate that human Ubc6e is an extremely unstable target for degradation at the ER.This degradation is mediated by the proteasome and is dependent in part on the catalytic activity of the enzyme itself. We conclude that Ubc6e is both a component and substrate for the mammalian ERAD pathway. The studies described in this proposal aim to identify the cis- and trans- regulatory factors involved in this degradation. We will determine the cellular conditions during which phosphorylation and stabilization of the enzyme are regulated, and address the implications of enzyme stabilization on ERAD functional output. Finally, we will assess the functional implications of proteolytic cleavage of Ubc6e at the ER membrane and subsequent localization to presumptive lysosomes. We will establish whether this reflects a novel mechanism for recruiting the degradative power of lysosomes to assist in the unfolded protein response specifically in higher eukaryotes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Industrial Innovation in Transition' (IIT) targeting Horizon 2020.

assistant: **Abstract**

Industrial innovation has changed fundamentally over the last ten years. Companies have widely adopted new tools such as open innovation, innovation networks and ecosystems, systemic innovations, public/private partnerships, crowd sourcing, social media, and demand based innovations. These new practices have improved the innovation capabilities of companies and brought new challenges to the traditional innovation policy instruments. This project will examine widely companies’ current use of new innovation practices around Europe and the best practice experience of their use. It will also evaluate existing innovation policy portfolios at national and European levels, and analyze the differences between innovation processes and management practices in different industrial sectors. The best practices and other results will be disseminated widely both to the European business community and governments to improve Europe’s innovation potential. International organizations such as the OECD and the ERT, industrial associations and government agencies are actively participating in the study and in the wide dissemination of its results throughout Europe. The study will cover key industrial sectors in 11 EU Member States, with a survey aiming to achieve a response from some 800 companies. Coverage includes countries classified by the EU as Innovation Leaders, Followers and Moderate Innovators. The project will produce a toolbox for use comparative studies in other countries and use the data base created by the study to benchmark their innovation capacity against the best European practice. Some countries have already indicated their interest to conduct comparative national studies.International research has widely shown the crucial contribution of high innovation performance to ec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The emergence and evolution of linguistic tone' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

This project will investigate the origins, acquisition, and evolution of linguistic tone: the use of pitch to distinguish between the meaning of words. Despite the typological ubiquity of tone, there is still no phonetic, structural, or psychological model that explains how and why tones emerge (or fail to emerge) in language after language, nor how they evolve once they are formed. This is because there has never been a systematic analysis of the principles that govern the evolution of tone systems. EVOTONE will provide the first comprehensive study of tonal emergence and evolution, combining detailed phonetic and perceptual studies of Himalayan and Southeast Asian minority languages with innovative experimental methodologies and large-scale computational analysis of the structural principles correlated with the emergence of tone. EVOTONE is guided by a novel hypothesis that, if correct, will have important repercussions for the study of sound change. The core idea is deceptively simple: rather than being the result of small, incremental changes in pronunciation, features like tone come about due to a sudden failure to articulate a particular aspect of a sound. If the risk of focusing on tone is to overemphasize a single feature, the potential reward is enormous: an opportunity to transform our understanding of how physical and cognitive pressures interact to shape human behavior and language change. The outcomes of this project will provide a new empirical foundation for the typology and evolution of tone systems; break new ground in the study of how structural and phonetic factors interact in sound change; and establish, for the first time, an empirically grounded set of principles of tonal evolution. In addition to resolving a number of outstanding questions about t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Business relationship management for the extended enterpise' (BURMA-X), addressing dissemination and exploitation.

assistant: **Impact**

The BURMA-X project constitutes an integrating R&D effort, seeking to develop and validate a unique, knowledge based Web platforrn for extended manufacturing enterprises. The project refers to Key Action I, Innovative Products, Processes and Organisation, TRA 1.7 Extended enterprise in particular. Therefore, within BURMA-X we will support the operation of extended enterprises by integrating suitable technologies into an Internet portal, developing additional functionality for cross organisational collaboration, as well as suitable process interfaces for cross organisational business process interoperability. BURMA-X will result to a holistic business relationship management for extended enterprises. Despite its strong industrial focus, BURMA-X significantly contributes to the Community Social Objectives.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Development of a process for the low cost manufacture of cementless orthopaedic prostheses with a novel cored biomaterial structure'.

assistant: **Innovation**

The specific industrial objective of this cooperative research project is to design, develop and demonstrate a novel manufacturing process capable of producing enhanced performance, cementless, orthopaedic prostheses with a novel cored structure. Development of such technology will satisfy the clinical objective of this work which is to provide extended life prostheses, reducing the number of revision surgeries required and thereby reducing the financial and resource demands placed on European health care providers, and also improving the quality of life of the European citizen. These objectives will be achieved through the fulfilment of technical objectives relating to:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Ultrafast Chirality for Life and Technology' (TRILOGY) targeting Horizon Europe.

assistant: **Abstract**

TRILOGY establishes the interface between the emerging field of Ultrafast Chirality and its Life and Technology applications by using attosecond electronic response to light, the fastest agent in mediating electric signals, highlighted by the 2023 Physics Nobel Prize.Chirality, a dissymmetry between a molecule and its mirror image, is a synonym of life: it enables metabolic reactions and stability of proteins. Abnormal chirality is an indicator for cancer cells, brain or kidney diseases, but its accurate detection requires a combination of high precision and speed, where attosecond response to light gives clear advantage to optical methods. Standard chiro-optical methods are fundamentally limited in accuracy by a ratio of molecular size to the light wavelength. Resolving ultrafast electron dynamics we remove this limitation and break into a new regime with chiral signals outperforming standard methods by severalorders of magnitude. We will take advantage of this paradigm shift in chiral measurements and develop new efficient ultrafast spectroscopies for discriminating medium sized chiral biomolecules and elucidating charge and spin transport in chiral media at the most fundamental level: the level of electrons. We overlap the training and innovation landscapes in a unique way inspired by a common drive to bring cutting-edge scientific developments to applications, enabled by strong involvement of industry. We will (i) integrate our methods with existing analytics for quick market adaptation, working with the market leader for mass spectrometry(ThermoFisher), (ii) further them to unprecedentedly high throughput enabled by laser technology (Amplitude) and state-of-the-art imaging (PIimaging). We will make a difference, motivate and inspire young minds, training a new gene
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Advanced techniques for precipitation estimates in alpine regions' (1998-2002), addressing dissemination and exploitation.

assistant: **Impact**

The main objective is to combine precipitation measurements from rain gauge and weather radar detain complex terrain optimally, i.e. by reducing bias and variance of the resulting precipitation analysis. A new method which takes advantage of the error independence of gauge and radar measurements and uses block kriging and Bayesian combination conjunctively was developed at the host institution. The innovation compared to traditional methods lies in the reduction of both bias and variance of the resulting estimates. The new method will be adapted for use with data gathered by gauges and radar in Austria's complex topography. The results of the new method will be compared to the results of the conventional techniques. Additionally a new theoretical non-steady state test case will be developed to test the performance of methods such as empirical exponential weighting or co-kriging as well as the new method. training and impact for applicant:* Bayesian and geostatistical methods for observational data analysis* new method of precipitation analysis that fully exploits radar and rain gauge measurements* learning from the leaders in the field* working in an internationally accepted and well known institution* impact of precipitation for hydrological and natural hazards (flooding) applications* preparation to work in natural hazards related jobs after the fellowship impact for host:* application of their new method to complex terrain* application of their new method in another EC country* development of a theoretical non-steady test case for various analysis methods
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Co-construction in the field of social welfare' in the context of a Horizon Europe call.

assistant: **Objectives**

COCOSO brings together 6 universities and 16 partners from the non-governmental and public sectors. This industrial doctoral network is dedicated to participation and co-construction as a core dimension of democracy and innovation in social welfare. Doctoral research and training are designed to address the pressing demand for meaningful and efficient participation of citizens involved in social services and policies: services users, practitioners, managers, decision and policy-makers. Citizens experiencing welfare systems are often subject to one or several factors of inequality and vulnerability, which directly or indirectly hinders their participation. To effectively address contemporary challenges in co-construction of social policies and practices requires the following steps: - identify different perspectives on participation and co-construction; - overcome power, trust and management barriers to embed co-construction in policies and services;- address limitations in co-construction due to vulnerability and cross-sectionality; - enhance the potential of digital tools for participation.These tasks will be fulfilled by researchers under close collaboration and supervision of senior academic and industrial partners from different disciplines including social policy, education, sociology, management and history; as well as different sectors such as local authorities and non-for-profit social organisations. Cocoso will thus contribute to develop: (a) research- and practice-based evidence and knowledge about barriers and facilitators to co-construction; (b) edge-cutting methods to embed co-construction in practice and collaborative research (networking of universities, NGOs, users, local authorities) and(c) effective implementation of co-construction by highly skilled r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Evolving evidence based treatment strategies for infantile hyperinsulinism using clinical, genetic and cell biological insights into a heterogenous disease' (1998-2002).

assistant: **Concept**

Infantile hyperinsulinism (HI) is a rare devastating heterogeneous genetic disease. Germ line or somatic mutations in one of four genes (resulting in loss / reduction of ATP dependent potassium currents in the pancreatic b-cell membrane) are founding 50 % of individuals. Overall 35% of patients have a somatic mutation within an abnormal focus of pancreas ( foHI ). The genetic basis in other patients is obscure. This proposal will(a) screen new candidate genes identified through study of clinical phenotype and b-cell biology in vitro;b) evolve strategies to identify foHI early and facilitate early specialist surgery in supra-regional surgical centres;(c) critically evaluate / develop new treatments for non-foHI;(d)establish a multinational patient / genetic database;(e) establish and cryopreserve HI b-cell lines for future genetic manipulation and transplantation studies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Intracranial Neuro Telemetry to Restore Communication', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Not being able to communicate while still being conscious is a horrifying prospective for many patients worldwide. Patients with motor neuron disorders, trauma or stroke risk losing complete muscle control leading to Locked-In Syndrome (LIS) which leaves them completely paralysed and unable to communicate. This is an intolerable, fearful situation with very low quality of life and extreme burden of care for patients, family, and care givers. Intracranial Neuro Telemetry to REstore COMmunication (INTRECOM) will provide a breakthrough for these patients by developing a novel, fully implantable Brain-Computer Interface (BCI) technology that allows for real-time speech decoding and use in the home environment. This BCI system will significantly transcend current technology by providing a high-resolution and sustainable device, combining state-of-the-art hardware and software solutions based on Artificial Intelligence (AI) to liberate LIS patients from their isolation.


**Keywords:** Neural engineering, Brain-Computer Interface, ElectroCorticoGraphy, Locked-In Syndrome, human, machine learning
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Shining through the Galaxy: dark matter signals versus astrophysical backgrounds' under Horizon 2020.

assistant: **Concept**

The nature of dark matter (DM) is one of the greatest mysteries in modern physics. It is well established to constitute 26% of the total energy-matter of the universe, to drive the motion of stars and galaxies, and to have shaped the universe as we observe it today. We know how DM interacts gravitationally with standard matter, but what we do not yet understand are its nature and particle properties.A general prediction of theoretical DM models is that dark matter particles self-interact producing high-energy photons and charged particles at rates detectable by current ground- and space-based telescopes. Discovering such a signal would allow us to study the particle properties of DM for the very first time.In a recent exciting development, an anomalous emission in the gamma rays coming from the centre of our Galaxy has been measured, the so-called Galactic centre GeV excess: this could be the very first signature of the presence of DM there. My project will carry out definitive tests of this putative first non-gravitational signature of the DM particle nature by studying the gamma-ray sky. Firstly, I will improve the sensitivity and reliability of searches for DM in the inner region of the Galaxy - one of the most promising targets - thanks to novel analysis methods. The unprecedented accuracy of the data available requires theory to provide robust predictions for the DM distribution in the Galaxy, which are currently missing. I will remedy this by using the most recent simulations of galaxy formation to predict the DM induced signal.My project will considerably boost astroparticle physics research towards the identification of the much-sought after DM by developing new methods for gamma-ray data analysis and for DM models testing. Owing to the designed program, I will