RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Naturally durable: Developing and testing the resilience of innovative natural admixtures for lime-based conservation mortars'.

assistant: **Concept**

Lime mortar is one of the most ancient and common building materials used by man for centuries, all over the world. Unfortunately, over the last two hundred years, lime has been progressively replaced by Portland cement, which has been used indiscriminately in the majority of deteriorated historic buildings. Because of the highly regrettable, irreparable damage caused by these wrong repair interventions, nowadays restorers and manufacturers have understood the importance of recovering lime to design traditional, sustainable, compatible and durable repair mortars. Notwithstanding, the industrial production of mortars has led to differences in the manufacturing techniques involved and the characteristics of the components used, with the consequence that ready-to-use (industrial) mortars do not show the same quality as traditionally prepared mortar.The overall aim of this research project is to design a suitable and durable ready-to-use lime mortar that can be used as repair material in historic buildings. To improve the quality of the mortar designed, we will use natural admixtures (i.e. derivatives of the vegetable and animal world) to modify some characteristics of mortar. The interest of studying and using these admixtures is clearly linked with the need of adopting sustainable industrial processes, which entail reduced pollution and energy consumption. This research will focus especially on the study of the durability of mortars prepared with such admixtures, towards different climatic conditions, pollution and microbiological activity. This study will be carried out by using chemical, mineralogical, petrographical techniques, as well as physical-mechanical and durability assays (accelerated and natural weathering tests). This research is innovative in the field of bo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Post-crisis urban governance transformations in Southern Europe: a comparativist approach'.

assistant: **Concept**

The post-crisis transformations of the socio-political landscapes in Southern Europe have shaped crucial opportunities for emergent political actors and the civil society to introduce new governance mechanisms. Following a turbulent period of social mobilizations, rapid political and institutional transformations are underway at the city, regional and national levels in countries such as Spain and Greece, and particularly in Madrid and Athens. These provide a crucial theoretical, methodological and analytical challenge for urban studies and a key opportunity for the development of a novel relational comparative approach regarding the modifications of urban governance in Madrid and Athens. The prime research aim of URBANiTE is to investigate the ongoing socio-political developments in the two cities, the relationship between civil society and emergent political actors and the ways these shape institutional changes. The project will produce context-sensitive, innovative outcomes on multi-level territorial governance, of high relevance for science, society and policy, in times of sweeping challenges in Europe and beyond. Moreover, it involves integrated interdisciplinary research with policy implications for the governance of inclusive, innovative and reflective societies, hence fully responds to challenges set out in the Horizon 2020 Societal challenges programme. The Fellowship will provide opportunity for knowledge exchange, as the fellow will bring expertise from the UK and Greece on urban politics, citizenship and grassroots social innovation in austerity contexts. It will also allow the fellow to advance her knowledge in an interdisciplinary research environment and learn from a new regional context, which will contribute to greater understandings of urban governance
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Advanced acoustic methods for leak detection and localization in aging water distribution networks' (WATER-LDL), addressing dissemination and exploitation.

assistant: **Impact**

This research project addresses the critical need for improved leak detection, localization, and monitoring in aging water distribution networks (WDNs), particularly in megacities like London, Paris, and Rome. These networks face significant challenges due to environmental degradation and aging infrastructure, resulting in frequent leaks that cause water wastage and infrastructure damage. Current acoustic leak detection methods are labor-intensive and prone to errors, relying heavily on human expertise, which limits their efficiency.The project aims to go beyond the state-of-the-art by investigating the fundamental mechanisms of leak signal generation in water pipes. By integrating experimental studies, computational fluid dynamics simulations, and theoretical modeling, the research will provide a comprehensive understanding of how leak signals are affected by factors such as pipe properties, soil conditions, and leak characteristics. This knowledge will be used to develop advanced algorithms for leak identification and localization, improving accuracy by filtering out background noise and enhancing time delay estimation.Furthermore, the project will propose a real-time monitoring strategy for WDNs, enabling proactive leak management and improving water infrastructure sustainability. The interdisciplinary approach combines acoustic and vibration analysis, signal processing, and infrastructure engineering, with collaboration from international academic partners.The expected outcomes include a universal leak detection model applicable to diverse WDNs, and the development of scalable solutions that can extend to industries such as gas, hydrogen, and oil. This project promises significant contributions to both water conservation and sustainable urban infrastructure.


**Key
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Environmental Governance in Latin America and the Caribbean:Developing Frameworks for Sustainable and Equitable Natural Resource Use'.

assistant: **Concept**

The central objective of this project is to understand how environmental governance is shaped in Latin America and the Caribbean (LAC) and to develop a new analytical framework for environmental governance in the region. The project will focus on both formal and informal practices of management around renewable and non-renewable natural resources, how they are perceived, contested and reshaped in the context of rapid and complex social, political, economic and environmental changes at local, national, and global levels. In order to do so, the concept of environmental governance provides a comprehensive approach linking theory and practice.Latin American and Caribbean countries have come to occupy a key position in the global debate on environmental governance, and the climate crisis has further stressed the international importance of the region. This project will focus on the obstacles and possibilities for sustainable production systems that can generate both economic development and a more equitable distribution of benefits in order to decrease poverty, exclusion, and environmental degradation in LAC. It will depart from the region’s experience with environmental governance, analyse recent initiatives, and explore options for institutional innovation and inclusive approaches towards natural resource use and management. The project will build on available ‘knowledges’ and generate new information which will be widely disseminated among all relevant user groups (social movements, academics, state institutions and private sector) to support them in developing future strategies and activities. The project will use multi-disciplinary and multi-scalar methods, including stakeholders in all the project phases to discuss and compare contexts and outcomes in different LAC reg
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Prompt Gamma Time Imaging: a new medical-imaging modality for adaptive Particle Therapy'.

assistant: **Concept**

Particle Therapy (PT) is potentially the most conformal and selective form of radiotherapy, but its clinical outcome is still limited, mainly because of the numerous sources of uncertainties affecting both treatment planning and delivery. The objective technical complexity of predicting and verifying the ion path in the patient has led to conservative treatments that, in order to increase safety, sacrifice efficacy. Having the full control of the dose gradient within the patient in real time would allow to fully exploit the ballistic advantage of PT. The healthy-tissue sparing effect can be enormous, further encouraging the use of PT for paediatric malignancies. Alternatively, the target dose could be increased to achieve better tumour control, and dose escalation procedures could be envisaged to treat radio-resistant tumours. With the aim of increasing both safety and efficacy, I propose a new medical-imaging modality to monitor PT treatments in real-time. It exploits the signal of secondary prompt gamma-rays emitted from nuclear interactions in the patients to recover information on ion range, tissue density and dose. I refer to this technique as Prompt Gamma Time Imaging (PGTI). An original reconstruction algorithm and a dedicated detector will be developed to prove the clinical advantages of PGTI, and bring this technique at the doorsteps of its clinical application. I will develop models to correlate the images provided by PGTI to real-time dose distributions, in order to enable the use of this technique for adaptive dosimetry. PGTI will be also explored as a potential approach to proton tomography. For the first time, it would be possible to control the uncertainties affecting both treatment planning and treatment delivery with a unique device. PGTI may be the mis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'NoE Research and facilities directed at instrumentation for manufacturing and analysis of single molecules and individual nanoclusters, targeted at life sciences' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Frontiers' aim is to provide Europe with a leading position in life sciences related nanotechnology within 4 years. In Frontiers there is a focus on analysis and manipulation of the bio environment. We will use the experience of the consortium in technology to create novel systems and our mutual interaction to conceptualise and design them. Frontiers creates centres of excellence in science as well as facilities. Partners concentrate more on focused, 'core areas', spend less effort on R&D/facilities outside these 'core areas'. Main elements of Frontiers are aimed at increasing the research efficiency, the infrastructural efficiency, the education efficiency and at building more and better business cases. The Joint Program of Activities (JPA) is grouped in 4 blocks:-Coordination of research, leading to a Joint Research Programme;-Implementation of a 'Virtual European Nanosciences Laboratory', to ensure efficient use of infrastructure as well as the availability of equipment for the researchers;-Creation of an integrated European Joint Curriculum on life sciences related nanotechnology;-Spreading of Excellence, with a focus on joint IPR management and on the development of new business cases (Science-to-Industry).Basics of the Frontiers consortium: individual excellence in science, excellent nanotechnology infrastructure, proven capability to initiate start-ups, outstanding relations with nanotechnology initiatives all over the world and a proven track record in cooperating with other members of the consortium.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Navigational jet grouting' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Objectives and content Urban development is now requiring that a large number of construction sites, e.g. for tunnels (railways, subways, roads, sewers, etc..), access shafts, rehabilitation of ancient structures, to be executed with restricted headroom or within very limited working areas. Market surveys show a growing demand for a clean and versatile foundation technology compatible with small work areas and without compromise on the quality of the final construction. An improved technique, Navigational Jet-grouting, is proposed which allows the construction of foundations with compact equipment, compatible with reduced working areas and with the following characteristics:  uses only a compact equipment, more compatible with underground working areas and yet capable to reach depths greater than 50 meters,  efficient, predictable and reliable results,  real-time assessment of the position and quality of the obtained foundation,  improvement over current working conditions. To achieve the above, the project will start from the existing jet-grouting process, and will use an innovative design of the drill string to integrate down-the-hole electronic instrumentation . It proposes an important series of new and related aspects:  the development of predictive design rules for the jetgrouting process,  the optimisation of the jet-cutting process through an optimisation of jetting nozzles and of jet characteristics,  the development of a navigational drilling system tailored to jet-grouting devices, and carried by a compact drilling equipment,  the development of intelligent sensors to assess, in real-time, the continuity of the foundation and its volume. The Consortium comprises two industrial end-users: a consulting engineer, specialised in the fields of geotechnique and fou
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Molecular, morphological, and functional requirements for gastrointestinal serotonin release'.

assistant: **Innovation**

Communication between the gastro-intestinal (GI) tract, the enteric nervous system (ENS), and the brain plays an important role in regulating our behaviour, and accordingly, impairments in this communication have been implicated in the pathogenesis of multiple disorders including obesity, diabetes, visceral pain, and inflammatory bowel diseases. A better understanding of the molecular and cellular mechanisms of gut-to-brain signalling will be critical for treating these disorders. An important group of cells in this context are enteroendocrine cells (EECs), and most notably enterochromaffin (EC) cells, which function as mechano- and chemoreceptors and signal by secreting serotonin, however the release process is poorly understood. Strikingly, these cells show molecular and morphological features that are highly reminiscent of neuronal synapses in the brain, raising the intriguing hypothesis that they may form synapse-like contacts that lie at the heart of their communication mechanism. To date, however, this hypothesis has been difficult to test due to the low spatial density of EC cells along the GI tract. Using a multidisciplinary approach combining intestinal 3D-organoid cultures, correlative light- and electron microscopy, electrophysiology, and single-cell RNA sequencing, this project aims to address the questions i) which molecular mechanisms mediate hormone secretion from EC cells, ii) what are the functional properties of the release process, and iii) how are local circuits organized to signal information to the ENS and brain. The results from this study will allow me to answer the fundamental question whether EC cells form functional synaptic connections, as well as providing a comprehensive overview over the functional and molecular properties of these ‘synaps
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Multi-level SiC Module for Aircraft applications' (MuSiCA).

assistant: **Innovation**

MuSiCA will design and supply a power electronic module and gate driver using silicon carbide devices for a relatively high frequency 100kW aircraft motor drive application. The power converter topology has been chosen and is provided as an input to the project. The main objective is to package silicon carbide devices in a manufacture-able and reliable power module package to enable silicon carbide technology to meet its full potential in terms of competitiveness against current solutions. The power module package will be integrated with the gate driver developed in the project. The hardware will be produced during the project and tested on an existing Clean Sky 2 funded motor drive test bed. The output of the project will be a demonstration of the manufactured hardware and evidence of its manufacturability, reliability and low weight and volume, and potential to reduce CO2, NOx and Noise emissions. The target application is European Aerospace but the solutions developed will be applicable to other applications such as automotive, rail and renewable energy, where high reliability and manufacturability is desirable. The key objectives of MuSiCA are to: Increase manufacturability, Increase long term in-service reliability, Increase modularity and scalability, Integration with Clean Sky test bed, Maximise the performance of silicon carbide power semiconductor devices, Enable the demonstration of the complete power converter. The power electronics module developed in MuSiCA will support the Clean Sky ambitions. It is expected that MuSiCA will directly address the ITD Systems and in particular will feed into the WP5 and WP 100.1: “Power Electronics and Electrical Drives” The CfP supports the activities within the Systems Integrated Technology Demonstrators by delivering an i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Determining the Epigenetic Mechanism of Centromere Propagation'.

assistant: **Concept**

The centromere is a unique specialized chromatin domain responsible for the nucleation of the kinetochore, a large proteinaceous complex that, during mitosis, powers and controls chromosome movement on spindle microtubules ensuring accurate chromosome segregation, thereby preventing aneuploidy, a major hallmark of human cancers. Although directly embedded in chromatin no specific DNA sequence is either necessary or sufficient to propagate the centromere which is specified largely in an epigenetic manner. The primary candidate for centromere identification is CENP-A, a histone H3 variant that assembles specifically into centromeric nucleosomes and nucleates the assembly of the entire centromere complex. How this epigenetic “mark” is initiated and stably maintained while the underlying genome is continuously duplicated as cells divide remains a mystery. This is due, in part, to the inability to track proteins long term. I have adopted a novel fluorescent pulse labeling technique to specifically tackle this problem and established the basic long term dynamics of centromeric CENP-A chromatin. Here, I propose to build on these initial results and further develop this state-of-the-art fluorescent labeling technology combined with high-end imaging to determine how epigenetic factors are maintained and replenished across cell divisions using the centromere as a model while also expanding the analysis to include other epigenetic components. Through these new cell-biological tools in conjunction with molecular genetic and biochemical assays, I have devised a multifaceted approach to identify factors mediating CENP-A assembly as well as to determine the role of centromeric DNA in the initiation of the epigenetic mark. Collectively, these efforts are aimed at elucidating the genera