RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'European e-freight capabilities for co-modal transport' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The key issues that will be addressed in e-Freight are:1.Intra-European trade is complicated due to disconnected logistic chains. This hindrance conflicts with the legitimate ambition of achieving a European maritime transport space without barriers. Linked to these issues is the broader need for simplification and harmonisation of regulatory requirements and accelerated development of EU and National Single Windows  to streamline traffic and cargo reporting to authorities particularly in the context of co-modal transport.  Further, safety and security issues need special attention, particularly in establishing efficient collaboration between authorities and transportation stakeholders to improve the development of capabilities for proactive and remedial measures to protect the environment as well as the security of freight transport networks.2.Optimisation of road, rail, and waterborne transportation resources to achieve co-modality requires improved ways for transport stakeholders to establish co-operation and to integrate their processes. For this, the “e-Freight” project will introduce Information Highways for Co-modality to denote solutions assisting transport operators to establish common end-to-end transportation processes incorporating regulations compliance and ‘intelligent’ monitoring and control.3.In centrally managed networks prevailing in transportation services, coordination is achieved through the network’s formal structure and central communications. The movement towards a much more open environment for the realisation of co-modality goals is dependent on transport service providers publishing their services in the internet in a manner that can readily be used by independent web based transport management systems. This requires both stakeholder engagemen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Unravelling the Evolution of Complexes with Ancestral Sequence Reconstruction' (EVOCATION) under Horizon Europe.

assistant: **Objectives**

Almost all proteins perform their functions as part of protein complexes. These assemblies are intricate and often beautiful examples of evolution?s capacity to generate complexity. But are they built by natural selection? My recent work has revealed that they may in fact be produced and maintained across vast time scales by neutral processes, even if they provide no adaptive benefit at all. In this proposal, I will test this radical idea by bringing together ancestral sequence reconstruction and quantitative biochemistry of protein complexes. I will use this approach to experimentally unravel the evolutionary processes that generate and maintain biochemical complexity in three model systems that exemplify archetypical protein-protein interactions:  In the first objective, I will unravel what drives the evolutionary gain and loss of homomeric interactions. I will recapitulate how the universally conserved enzyme citrate synthase repeatedly underwent changes in self-assembly state. I will test if these changes were adaptive or whether they result from new interfaces being highly evolvable. In the second objective, I will probe why protein complexes evolve to depend on transient interactions with folding and assembly chaperones. I will retrace how the CO2 fixing enzyme RubisCO acquired a set of dedicated assembly and folding chaperones.  I will unravel whether the initial gain of new chaperone interactions was useful and determine what later caused RubisCO to start completely depending on them. In the third objective, I will unravel if many of the interactions between different complexes are caused by neutral evolution. I will use a new experimental approach in yeast to quantify the rate at which complexes gain interactions with the rest of the proteome by chance alone.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Mixed (ar)rivals:  Perceptions of threat, inequality, and the risk of violence between different (forced) migrant groups in North Africa', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Host communities often perceive certain refugee or migrant groups as more ‘threatening’ (e.g. security or employment) than others. This can be seen from the recent arrivals of Ukrainian refugees in Europe, but also in many other regions of the world. In Morocco, for example, Sub-Saharan migrants are less favored than others. Unequal treatment by nationality, ethnicity, or time of arrival regarding status, access to employment or residence is often the consequence. Yet, little is known about what impact this has for inter-migrant group relations. How do (forced) migrant groups perceive other migrant group arrivals? Do they consider each other as potential rivals, as to say as competitors or threats? What factors increase or decrease inter-migrant group rivalries and when might they turn violent or rather solidary? MixedRivals applies a novel interdisciplinary approach by analyzing structural (ex. exclusionary policies) as well as socio-psychological factors (ex. perceptions of threat, positive contact, and group identification), bringing together theories on inter-group relations from migration, violent conflict, rivalry, and psychology. MixedRivals moves beyond the common host-migrant focus, and pushes the conceptual boundaries of rivalry, refugee/migrant, violence/non-violence, liberal/restrictive policies further, introducing the concept of “mixed rivalries” underlining the complex and multi-dimensional nature of possible contestations between migrant groups. Using a mixed method approach, furnishing new cross-sectional survey and qualitative data on inter-migrant group perceptions of threat and inequality in four urban hubs in North Africa, as well as de facto (forced) migration policy data, the project aims at advancing the understanding of inter-migrant group relat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Advanced control and supervision of processes and production systems' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Research Training which is provided: Advanced regulation, Design of multivariable controllers, Advanced process control lab work, Petri nets Analysis & control of production systems, Rem time & local area networks, Artificial intelligence, Optimal filtering, Constrained optimization, Performance evaluation of production systems, ...Expertise available: More than 35 permanent researchers work in the field of analysis, modeling, control & supervision of processes & production systems, ranging from theoretical developments to practical applications through methodological studies. The domain of application of these studies ranges to various types of processes, including electrical, mechanical, chemical processes, transportation systems, food industry, biotechnology, production systems, manufacturing systems, communication systems, etc. Qualification /experience required: The applicants should have a good background in automatic control and/or production systems at the level of a master thesis, some experience in the use of classical software (for automatic control) and ability in conducting methodological research.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'A WALK-BY BIOMETRIC IDENTIFICATION SYSTEM BASED ON FACE RECOGNITION' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Security is becoming an integral part of strategies and measures implemented by industry and public authorities in order to maintain high standards of personal protection and quality of life. Access control is a key element of any security concept. It is essential that only authorised persons can access specific locations and/or information. Attempts at unauthorised access have to be detected and prevented. Automated biometric identification systems are increasingly recognised as a means for personal identification based on unique physical characteristics rather than possession" (ID card) or "knowledge" (PIN code). Amongst existing biometric technologies only face recognition has a realistic potential to work in a remote fashion (several meters distance between person and sensor) under real-time requirements. The goal of the WABY project is to validate a novel 'walk-by' biometric identification system, realised by a combination of real-time face recognition and hands-free RF card technology. People carrying a proximity card are automatically identified approaching a check-point while a video camera system simultaneously captures an image of the person's face. The highly innovative combination of automated face image verification, and hands-free ID card technology will for the first time realise a convenient and secure access control system. The WABY access control system will use existing face recognition technology (ZN-Face by ZN GmbH) for still images and face recognition technology (FaceSnap by C-VIS GmbH) for real-time video. An innovative long range RF card reader by Nedap NV will complement the vision technology. Supporting end-users are Rabobank and Schiphol Airport who will run pilot installations and evaluate the system with respect to their needs. The major ob
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Biomarkers of renal graft injuries in kidney allograft recipients' (BIOMARGIN).

assistant: **Innovation**

In renal allograft recipients, 10-year graft survival has not improved over the past decades. Histological examination of graft biopsies has long been the gold standard to confirm graft injuries, but biopsies are invasive and histological grading is not very robust. There is thus a need for robust, non-invasive methods to predict and diagnose acute and chronic graft lesions, to improve patient treatment, quality of life and long-term graft survival. Also, there is an unmet need for better understanding of the immune and non-immune mechanisms of interstitial fibrosis /tubular atrophy and graft loss.Combining all the skills required to build upon previous findings, BIOMARGIN will offer such opportunities in renal transplantation by integrating several omics approaches (mRNA, miRNA, peptides, proteins, lipids and metabolites) in blood, graft tissue and urine, in a well thought out, multistage discovery-to-validation translational programme, following the highest European ethics and regulatory requirements, as well as quality controls and quality assessments at all clinical and analytical steps. It is probably one of the first programmes to pursue such an integrated and systematic research approach.BIOMARGIN aims to: (i) discover, select and validate blood and/or urine biomarkers of renal allograft lesions in adult and pediatric kidney transplant recipients; (ii) provide renal transplant physicians with non-invasive, robust diagnostic tests and interpretation algorithms enabling closer, more accurate, more predictive and/or less invasive monitoring of transplanted patients; (iii) help to avoid or diminish the use of biopsies and improve patient treatment, quality of life and long-term graft survival; (iv) help understand the mechanisms involved in the allograft injury proce
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Redefining Variability: Evaluating Land Use and Transport Impacts on Urban Mobility Patterns' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Urban mobility analysis, advanced by the emerging fine-granularity location data (e.g. smart card data, mobile phone data and social media data), has received significant attention in recent years. It has become an important subject for understanding the functionality, ever-increasing dynamism and complexity of urban space. realTRIPS aims to open a new avenue of research in urban mobility analysis using emerging automatic data by developing an analytical and modelling framework, particularly addressing variability across spatial-temporal scales. I argue that the variability of urban mobility should not be simply interpreted as a number of errors, but indicators of changes in regular human behaviours impacted by land use and transport at different scales. A deeper understanding of variability and regularity would contribute to a more accurate prediction of urban development scenarios. The relevant theories and measures on variability have been long-researched in spatial statistics, but not well applied to the context of urban mobility studies. The proposed framework will take advantage of the research progress in multi-disciplines and leverage key concepts from uncertainty in spatial analysis, time geography, and land use transport planning. Under such framework, variability will be measured in mobility patterns and integrated as a function of space and time into operational urban models for predicting impact of land use and transport on people’s travel and location choices at different spatiotemporal scales. Case studies presenting typical urban contexts (i.e. London, Shenzhen, Nairobi) will be explored to demonstrate the feasibility and generic applicability of the theory, analytical methods and urban models.


**Keywords:** urban mobility, variability, mobility patter
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Modelling of unsteady combustion in low emission systems' to be submitted under Fifth Framework.

assistant: **Abstract**

All low emissions combustion systems suffer from acoustic instability, and this is often the major issue preventing wide application of the technology. This proposal addresses the issue of how this important combustion phenomenon should be represented in design tools. Experiments are proposed which will identify the mechanisms by which acoustic disturbances cause variations in the aerodynamics or fuel spray behavior. These in turn give rise to heat release variations, thus establishing the feedback mechanisms that cause damaging pressure waves. These results will form the basis of a design methodology to prevent such oscillations occurring.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Characterisation of tissue vascularisation by magnetic resonance imaging. Quantitative aspects of micro-angiography and perfusion mri experiments for functional imaging' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Our objective is to implement magnetic resonance imaging (MRI) techniques providing bio-scientists and physicians new informations on tissue vascularisation and perfusion. Particular emphasis will be put on the quantitative aspects of the measurements and on fast acquisition schemes which enable dynamical studies. Applications notably include functional MRI, the characterisation of tissue hypoxia and ischemia situations and of tumour growth. These fields interest both the host group and my source laboratory, the first one particularly in the context of brain studies. Concretely, the intended work will consist in developing, practically implementing and assessing the most appropriate angiography and perfusion techniques for our purpose. Their limits (minimum spatial and temporal resolutions, reliability; quantitative aspects) will be analysed both theoretically and experimentally, as well as will be their dependence on controllable physiological and acquisition parameters. In vivo animal models on high-field imagers will first benefit from the results before to consider clinical studies on human volunteers. Training content (objective, benefit and expected impact) I have been working for several years as a physicist in a team of biologists and chemists. It would be of uppermost interest for me to train within a group more oriented towards the physical aspects of MRI. By learning new techniques and by working on more diversified and up-to-date systems, my experience will be enlarged. Moreover, the acquired technical skills will strongly benefit my origin laboratory, whose mastery of contrast agents will turn be most valuable when developing MR micro-angiography experiments in the host group (know-how exchange between European laboratories impact). Links with industry / in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The determinants of cross-seeding of protein aggregation: a Multiple TANGO' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Amyloid-like protein aggregation is a process of protein assembly via the formation of intermolecular β-structures by short aggregation prone sequence regions. This occurs as an unwanted side-reaction of impaired protein folding in disease, but also for the construction of natural nanomaterials. Aggregates appear to be strongly enriched in particular proteins, suggesting that the assembly process itself is specific, but the cross-seeding of the aggregation of one protein by aggregates of another protein has also been reported. The key question that I aim to address in this proposal is how the beta-interactions of the amino acids in the aggregate spine determine the trade-off between the specificity of aggregation versus cross-seeding. To this end, I will determine the energy difference between homotypic versus heterotypic interactions and how differences in sequence translate into energy gaps. Moreover, I will analyse the sequence variations of aggregation prone stretches in natural proteomes to understand the danger of widespread co-aggregation. To achieve these outcomes, I will study the interactions and cross-seeding of aggregating proteins and model peptides in vitro and in cells. I will extract the sequence and structural determinants of co-aggregation, and employ these to construct novel bioinformatics algorithm that can accurately predict co-aggregation and cross-seeding. I will use these to analyse co-aggregation cascades in natural proteomes looking for mechanisms that protect them from wide-spread cross-seeding. This work will have a significant impact on the understanding of the downstream effects of protein aggregates and may reveal co-aggregation networks in human diseases such as the major neurodegenerative diseases or cancer, potentially opening up new re
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Toll-Like Receptor 4 activation and function in diseases: an integrated chemical-biology approach.' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Based on an international team derived from the COST action BM1003 (www.cost-bm1003.info, 2011-2014) and thus relying on consolidated group interactions and synergies and on a unique combination of chemistry, biology, biophysics, biochemistry and pharmacology expertise, the TOLLerant project aims to gain information on molecular aspects of TLR4 activation and signaling by using synthetic and natural compounds and nanoparticles that interact selectively with some components (mainly MD-2 and CD14) of the TRL4 recognition system. TLR4 is an emerging molecular target related to an impressively broad spectrum of modern day disorders still lacking specific pharmacological treatment. These include autoimmune disorders, chronic inflammations, allergies, asthma, infectious and CNS diseases and cancer. The short-term scientific objective is to develop novel, non-toxic, synthetic and natural TLR4 modulators (agonists or antagonists) and to assess their therapeutic potential on animal models of TLR4-related acute and chronic pathologies that still lack efficient pharmacological treatment. The long-term scientific objective is to develop a new generation of innovative, TLR4-based therapeutics, to be used as vaccine adjuvants, anti-sepsis agents, and anti-inflammatory agents to treat chronic inflammations (allergy, asthma). The training programme will provide Early Stage Researchers (ESR) with broad competences, experience and skills in the cutting-edge, inter-disciplinary research in the field of chemical biology related to the molecular mechanisms of innate immunity and inflammation. During the training, the young researchers will be supported by senior scientists to cultivate their scientific, entrepreneurial and inter-cultural mindset. The non-academic sector will be committed to