RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Evolutionary principles of nuclear dynamics and remodelling'.

assistant: **Objectives**

Every eukaryote has a nucleus, a double lipid membrane-bound compartment that encapsulates the genome, but almost every nucleus is different - in shape, size, molecular composition, spatial organisation, and dynamics through the cell cycle. Given its fundamental and universal functional roles in protecting the DNA and regulating the exchange of information and control machinery between genome and cytoplasm, one might ask the question: why are there so many ways to build and remodel a nucleus? Bringing together comparative genomics, phylogenetics, quantitative cell biology and experimental evolution in multiple microbial model systems drawn from across the eukaryotic tree, we set out to elucidate the genomic, biophysical and evolutionary factors that determine nuclear dynamics and remodelling - karyodynamics - within the context of cellular architecture and function. A comparative perspective driven by phylogenetics will enable us to separate universal principles of karyodynamics from species- and niche-specific adaptations, and dissect the reasons for the evolutionary and developmental plasticity that we observe experimentally. In turn, we can use these principles to infer, predict and validate phenotypes in novel and emerging model systems. Finally, a more comprehensive understanding of the mechanisms responsible for karyodynamic phenotypic diversity would allow us to reconstruct evolutionary trajectories all the way back to the origins of the nuclear compartment, a landmark event in the evolution of eukaryotes from an archaeal-bacterial symbiosis over 2 billion years ago.


**Keywords:** Evolutionary cell biology, nuclear remodelling, emerging model systems
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Parallel SOftware framework for time-CRitical mAny-core sysTEmS'.

assistant: **Concept**

The recent technological advancements and market trends are causing an interesting phenomenon towards the convergence of High-Performance Computing (HPC) and Embedded Computing (EC) domains. On one side, new kinds of HPC applications are being required by markets needing huge amounts of information to be processed within a bounded amount of time. On the other side, EC systems are increasingly concerned with providing higher performance in real-time, challenging the performance capabilities of current architectures.<br/>The advent of next-generation many-core embedded platforms has the chance of intercepting this converging need for predictable high-performance, allowing HPC and EC applications to be executed on efficient and powerful heterogeneous architectures integrating general-purpose processors with many-core computing fabrics. To this end, it is of paramount importance to develop new techniques for exploiting the massively parallel computation capabilities of such platforms in a predictable way.<br/>P-SOCRATES will tackle this important challenge by merging leading research groups from the HPC and EC communities. The time-criticality and parallelisation challenges common to both areas will be addressed by proposing an integrated framework for executing workload-intensive applications with real-time requirements on top of next-generation commercial-off-the-shelf (COTS) platforms based on many-core accelerated architectures. The project will investigate new HPC techniques that fulfil real-time requirements. The main sources of indeterminism will be identified, proposing efficient mapping and scheduling algorithms, along with the associated timing and schedulability analysis, to guarantee the real-time and performance requirements of the applications.<br/>The technol
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Insurgent Temporalities: Fascism as a Global Anti-Universalist Project'.

assistant: **Objectives**

Deploying a complex methodological apparatus drawing on transnational history, this project breaks new ground by providing an original global history of fascism (1919-1945). INTEMPO argues that the fascist national revolutions were part of a global project of overhauling the liberal international order and replacing it with a fascist one. It does so by approaching transnational fascism through the lens of temporality, showing the centrality of a specific temporal structure to fascist ideology. Fascists everywhere repurposed a historical or mythical past, saw their present as a watershed moment in world history, and aimed to accelerate it toward a redemptive future of eternal plenitude when time would stand still. Despite significant variation related to the different national contexts in which fascist movements and regimes emerged, the compatibility of this temporal structure – translating spatially into distinct but similarly compatible projections of a ‘New Order’ – allowed mutual recognition and enabled international cooperation that transcended fascism’s ultra-nationalism. The project further shows how fascism’s temporal imagination resolutely opposed the universal time regime associated with the spread of capitalism, liberalism, and colonial expansion. Fascist temporalities and their revolutionary potential are consequently used as an entry point for elucidating fascism’s restructuring of space – social space internally and geopolitical space internationally – and its complex engagement with capitalism and colonialism, respectively. The focus on temporality, underpinning analysis of the diverse forms that interactions between fascist movements and regimes took, allows us to operate across different spatial scales of analysis, from the local through the national to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'V4F' (V4F) under Horizon Europe.

assistant: **Objectives**

V4F aims to show proof-of-principle of a new technology capable of unprecedented control over interactions with specially synthesised targets to significantly improve the energy balance of aneutronic fusion reactions.New concepts and advanced simulations of inertial confinement of aneutronic fusion reactions and particle acceleration will inform pioneering experiments in high-energy matter-interactions. Results could offer the prospect of breakthrough increases in alpha-particle yields from fusion reactions and mitigate the instabilities found in conventional fusion reactions.This work offers the tantalising possibility of aneutronic fusion as a waste-free nuclear energy source and radical new configurations of particle accelerators, leading to an efficient positron beam acceleration. The results will benefit society with game-changing new approaches to clean, safe energy production and significant downscaling of positron accelerators with dramatic impacts in medicine, industry and fundamental science.


**Keywords:** USP laser, light votices, orbital angular momentum, fundamental interactions and fields, borane synthesis, particle acceleration, aneutronic borane fusion reactions
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Strategies for Assessment of Inquiry Learning in Science'.

assistant: **Objectives**

The aim of this proposal is to support teachers in adopting inquiry based science education (IBSE) at second level (students aged 12-18 years) across Europe. This will be achieved by utilising existing resources and models for teacher education in IBSE both pre-service and in-service. In addition to SAILS partners adopting IBSE resources within their curricula and implementing teacher education in their countries, the SAILS proposal aims to develop appropriate strategies and frameworks for the assessment of IBSE skills and competences and prepare teachers not only to be able to teach through IBSE, but also to be confident and competent in the assessment of their students’ learning. Through this unified approach of implementing all the necessary components for transforming classroom practice, i.e. teacher education, curriculum and assessment around an IBSE pedagogy, a sustainable model for IBSE will be achieved. SAILS will provide teacher education workshops in IBSE across the twelve participating countries and promote a self-sustaining model encouraging teachers to share experiences and practice of inquiry approaches to teaching, learning and assessment  by building a community of practice.  The SAILS consortium of over 60 partners from 14 organisations, including universities, a small-medium enterprise and an international multinational organisation, will work together to promote and disseminate inquiry based approaches to science teaching, learning and assessment with national and international stakeholders.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Advancing Green Deal Principles in sMart FacAde TechnoLogies for the construcTion sEctor based on AI, Data & Robotics' (AMALTEA) under Horizon Europe.

assistant: **Objectives**

AMALTEA’s main objective is to streamline the use of robotics, AI and data in the construction sector to reduce the energy use, resources and waste, increase safety, and improve processes’ reliability and product quality to adapt to the new demands from end users and Green Deal objectives. For that, the curtain-wall façade value chain will be reshaped by digitalizing the design, manufacturing, installation and disassembly/recycling phases. This approach is supported by the development and combination of several digital tools that will be integrated, together with technical solutions provided by SMEs and start-ups through FSTP, in Digital Solutions that will be validated in four pilots to improve the sustainability, efficiency, safety and automation of the façade value chain, and thus, building construction. The global solution will consider human in the loop for collaborative robotics and will use existing technologies to guarantee the safety use of the data across the entire process. Piloting will include: 1) AI parametric design and extended digital twin with all the data workflows along the façade value chain, 2) Digitalized façade manufacturing line in FDB facilities in Hungary, 3) and 4) Implementation of the solutions in operational construction environments (Residential/Hospital typology in the South of Europe and Offices/Tertiary typology in the Center of Europe). The project involves companies from all necessary disciplines, including: design, AI and data, robotics, manufacturing, construction, SSH (to have special care related to the communication between humans and the technologies developed). Additionally, the project will establish a collaboration with external SMEs (up to 25 projects) across Europe through a FSTP scheme to improve all the challenges define
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Genetics of predisposition to radiation-induced cancer of the thyroid' to be submitted under Fifth Framework.

assistant: **Abstract**

Carcinoma of the thyroid is a serious public health problem in populations at risk of exposure to radio nuclides accumulating in thyroid tissue. However, due to genetically determined differences in individual susceptibility to ionising radiation, simple dose-response relationships do not exist. Identification of those subjects who are predisposed to developing thyroid tumours would be of value for setting individual exposure limits and for tailoring post-exposure monitoring. The GENRAD-T consortium aims to identify the gene loci that are responsible for determining individual susceptibility to thyroid cancer. To do this we will use a mouse model of radio iodine-induced thyroid cancer combined with molecular genetic screening methods (QTL-mapping, micro satellite allelotyping and CGH). The applicability of the gene loci thus identified for use in human populations will be confirmed by analysing human thyroid tumours.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Integration of concepts for the parallelization of image processing algorithms into parallel compiler technology' (1994-1998).

assistant: **Concept**

The main focus of the project is to include concepts for the explicit parallelization of algorithms from the area of image processing and pattern recognition into modern parallelizing compiler and run time system technology. Massively parallel image processing systems require a very high bandwidth and have to exploit the communication facilities of the parallel system as far as possible. Application adapted data distribution schemes will be investigated for several algorithmic classes. Those include static and data dependend algorithms, e.g. scale space and multigrid methods. Based on the already developed concepts for explicit parallelization methods and the research on new algorithmic classes the results will be included in the Vienna Fortran Compiling Systems. The work will form a basis for general purpose parallel image processing software, that is efficient and easy to implement. Major stimulations for new applications in the area of image processing and parallel compiler systems are expected.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Endothelial Cells - an Overlooked Non-hematopoietic cOmponent of tuMor immunitY' (ECONOMY) targeting Horizon 2020.

assistant: **Abstract**

Despite decades of research, cancer remains the second leading cause of death globally. Amongst all cancers, lung cancer is the deadliest in both men and women worldwide. Immune checkpoint blockade (ICB) recently emerged as promising cancer therapy. While extremely successful in hematopoietic cancers and melanoma, success in lung cancer is very limited. We are therefore in desperate need to devise novel treatment strategies. One approach would involve remodelling the lung cancer immune landscape to improve clinical response to ICB. A so far overlooked non-hematopoietic component of the immune system which potentially greatly contribute to tumor immunity are endothelial cells (ECs). Most intriguingly, tumor EC (TEC) subsets expressing diverse immune markers were identified, in parallel with the discovery of diverse metabolic phenotypes in TECs. The host lab identified TECs with transcriptional signatures related to antigen processing and presentation (MHCII+). However, the functional significance of MHCII+ TECs in tumor immunity and whether their immune-related functions could be regulated by underlying metabolic programming is unknown. Given the strategic ""first line"" location of TECs in the tissue, the question is whether, ICB’s effectiveness can be partly attributed to TEC immunity. I therefore propose to investigate the interactions between MHCII+ TECs and T cells and the effects of such interactions on tumor immunity using state-of-the-art inducible EC-specific MHCII knock-out mice. Moreover, I will assess metabolic signatures in immune-TECs and test potential metabolic regulation of TECs’ immune functions. Such metabolism-driven regulation could open new therapeutic possibilities, utilizing already available pharmaceutical inhibitors to remodel the tumor immune l
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Ethics and the Obestity and Overweight Epidemic: Image, Culture, Technologies and Interventions' (EUROBESE) targeting Sixth Framework.

assistant: **Abstract**

Overweight and obesity are according to the WHO a major threat for in our century. Worldwide. Many EU and non-EU countries have or consider interventions to prevent overweight and obesity by influencing the lifestyle of citizens. Such interventions are no t morally neutral. The may cut deep in the individual persons life because they involve essential views an values regarding food and eating, appearance and image, the impact of biological and socio-cultural technologies and freedom. This project analyses the ethics of interventions to prevent overweight and obesity. Interventions have to be effective and ethically justified in the light of ethical principles such as privacy, justice, individual and cultural identity and autonomy, and societal interference. Ethical justification does not take place in a moral vacuum. One needs to understand the moral and cultural climate, the similarities and differences between countries. The ethical issues have to be analyzed in the light of cultural norms and values rega rding: the image of obesity and overweight, food and eating, physical exercise and fitness, and their relation to individual lifestyle and personal responsibility. These issues structure this project: its ultimate goal is to provide an ethical framework fo r the evaluation of interventions to prevent overweight and obesity. Such a framework must rest on sound foundations. Therefore a multidisciplinary consortium will analyze cultural values, norms, traditions regarding the image of obesity and overweight, the culture of eating, the present and future biological and socio-cultural technologies in the light of ethical notions. The project has both practical and theoretical aims. Its aim is to look at a huge and urgent problem from the perspective of ethics.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'SUSTAINABLE JET FUELS FROM CO2 BY MICRO-ALGAL CELL FACTORIES IN A ZERO WASTE APPROACH' (ALFAFUELS) targeting Horizon Europe.

assistant: **Abstract**

ALFAFUELS proposes a novel Sustainable Aviation Fuels (SAF) production technology that can play a major role in the decarbonisation of the aviation sector by replacing conventional fossil fuels in mid and long-term. ALFAFUELS contributes to climate change mitigation, energy transition, and on the establishment of a circular bio-based economy by providing a direct capture and utilisation of CO2, by developing cost-effective and sustainable technological solutions in all process steps, and by providing integration possibilities with other sectors. The project’s aim is to tackle the key challenges preventing SAF technologies to reach technological maturity and commercialisation such as the high current production cost, sustainability issues associated with their production, technological constraints (yields and efficiencies). To that end, ALFAFUELS includes targeted technological breakthroughs, such as the microbial production of a volatile fuel precursor from CO2, the upgrade to kerosene-type jet fuel molecules in ambient conditions using solar light-driven photochemistry, and the valorisation of all cell components in a biorefinery approach to co-produce starch and H2 (indirectly from CO2) as an important intermediate. The proposed technological novelties are combined with modelling approaches to maximize efficiencies, to optimize the overall process regarding cost and energy consumption and to evaluate the process with combined techno-economic and life cycle assessments. The project lifts the production technologies at TRL5, by including the design of novel cost-efficient bioreactors, pilot scale trials on real, industrially relevant CO2 streams and evaluation of the produced molecules against ASTM standards. To further accelerate the upscaling of ALFAFUELS, we analyse