RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Building a comprehensive burden sharing framework to inform on an equitable implementation of the Paris Agreement' (Equity-Paris) targeting Horizon Europe.

assistant: **Abstract**

Methodologies for assessing the ambition of national climate pledges are in theory guiding international negotiations processes under the UN. To this end, pledges are compared to national emissions scenarios that represent an equitable share of the global scenarios and of the effort they require to achieve the Paris Agreement goals. These equitable national emissions scenarios do not yet inform how they can be achieved through a combination domestic action and international cooperation though transfers of mitigation outcomes. As discussions move beyond pledges into action, informing subnational emissions objectives and international finance in line with the Paris Agreement and its equity principle can help implement mitigation globally.Internationally, global socio-economic scenarios inform the cost-optimal geographic distribution of mitigation effort, hypothesising sufficient finance. Equity-based scenarios provide the total effort that each actor should provide, possibly through international support. The difference between the scenario sets represents international finance that developed countries can use to fund part of their fair share in developing countries. Subnationally, state and city governments often aspire to deliver mitigation beyond their fair shares of the national targets and align with the Paris Agreement goal. A multilevel quantitative ambition assessment framework can serve as a basis to discuss the respective roles and efforts of subnational governments as part of a country or of subnational alliances.This project seeks to quantify 1) subnational emissions trajectories consistent with the Paris Agreement goals and 2) the international emissions mitigation support that each country can receive or provide to fulfil its equitable emissions scenario cos
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Life cycle approach and human risk impact assessment, product stewardship and stakeholder risk/benefit communication of nanomaterials', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Nanomaterials have a great market potential for SMEs due to the high added values and the reduced batch sizes compared to their corresponding conventional  bulk materials. Unless the benefits the introduction of nanomaterials is hampered due to the unknown human and ecological risks. It may take many years to fill  all knowledge gaps. However, the SMEs have to address the various different aspects and perceptions of risks, in communication with the various stakeholders. For this reason, SMEs need guidance to assess the risks and the benefits of their nanoproducts in comparison with the conventional (non-nano) products.The main goal of this project is to develop a structured life cycle approach for nanomaterials that (1) enables  to balance health/environmental risks of nanomaterials  in view of paucity of data against their benefits and (2) that further allows a comparison with the risks and the benefits of the conventional (non-nano) products. This  structured approach will be the base for a completely new service available to SMEs working with nanomaterials.As proof of principle and concrete benefit for the SMEs, LICARA will deliver guidelines to the members of the SME Associations to support them in their communication with regulators, clients and investors and to improve the production processes and/or applications of their specific nanoproducts.The consortium consists of 1 European and 3 national SME Associations, 2 SMEs, 3 RTDs and 1 project services company. The consortium is built in a way that the needed different expertise is represented. The partners are active in a range of (inter)national initiatives such as FP7 projects on life cycle assessment and risk assessment, OECD, ISO and CEN.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Supporting Mental Health in Young People: Integrated Methodology for cLinical dEcisions and evidence-based interventions' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Anxiety disorders’ diagnosis, decision and treatment processes are still uncertain and inconsistent especially in a fast-evolving real world where stressors affect people in different ways. SMILE aims to improve the quality of mental health management and ensure affordable services by sharing information, providing scalable digital tools, and ensuring personalized decision-making and evidence-based interventions in an effective way. To achieve these goals, SMILE will develop mainly Open Knowledge Platform (OKP) and interactive gamification tools. OKP will bring together healthcare professionals, scientists, policymakers, businesses, and citizens to co-design effective decision strategies and unlock access to meaningful knowledge. Gamification will provide self-assessment, learning, and self-care services for young people to develop thinking, coping, and doing skills. Hence, SMILE will be able to integrate and analysis at least 7 different diagnostic data from clinical data to daily living parameters. Also, SMILE will assist primarily clinicians and help patients through 3 decision-making tools. The analytics and predictive tools will support practitioners in understanding the associations between risk factors, and anxiety, and recommending interventions in a personalized way. The SMILE digital tools and services will be implemented and validated in eight real-life strategic case studies, in 7 different European countries: UK, Germany, Cyprus, Poland, Slovenia, Spain and Italy, to reach TRL 7. Also, a systematic upscaling method will be deployed to sustain our program and ensure the continuity in the post-project. SMILE will deliver durable legal, socio-economic, gender and environmental values for the benefit of healthcare professionals, patients, EU SMEs and society at
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Exploring the targeted delivery of biopharmaceuticals enabled by glycosylation control' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Most biotechnological therapeutics used in the clinic today and under current development, are of protein nature. Eukaryotic expression systems (such as yeasts and mammalian cells) for these therapeutic proteins add carbohydrate moieties (glycans) to the proteins, and these glycans strongly modulate the protein's in vivo biodistribution and therapeutic efficacy. Until recently, no adequate tools were available to accurately control glycosylation structure in these expression systems, but bio-engineering research in our lab and elsewhere has now largely overcome this problem.In the GlycoTarget ERC Consolidator grant project, we aim at exploring the relation between the structure of the glycans on therapeutic proteins and the in vivo targeting properties of these modified proteins to different tissues/cells/subcellular organelles.As highly medically relevant test cases for this exploration, we have selected three diseases with strong unmet therapeutic need, that could potentially be treated with glyco-targeted biopharmaceuticals through three different routes of protein delivery: progressive liver disease (intravenous), allergic asthma (subcutaneous immunization) and active tuberculosis (intrapulmonary delivery).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Integrated BIOrefinery to VALorize CO2 and biomass for the co-production of advanced biofuels and bioproducts'.

assistant: **Concept**

The EU aims to reduce the overall energy demand and supply energy in a climate-neutral way. For that aim, energy must be sustainable, cost-effective and safe, by boosting innovative technologies. In this sense, the EU describes the Key Strategic Orientation C: “Making Europe the first digitally enabled circular, climate-neutral and sustainable economy through the transformation of its mobility, energy, construction and production systems”. Therefore, it is mandatory to develop new energy technologies that are circular, environmentally friendly, affordable, safe and socially positive. By 2030, the EU aims to have a 40-45 % renewable energy share with 2.2 % advanced biofuels by 2030 and to be climate neutral in 2050. BIOVAL is a 36-month action that will create, develop and scale up an integrated energy-driven circular biorefinery with near zero-waste and zero-carbon emissions. It is based on a multi-feedstock concept, allowing the valorization of biogenic CO2 emissions and biomass wastes. The biorefinery also targets a multiproduct operation by the feasible and sustainable production of biofuels (advanced algal Hydrotreated Vegetable Oil-HVO, bio-H2, biogas/CH4, and IPA) and high-added value bioproducts like pigments (e.g., astaxanthin), using microalgae and bacterial gas fermentation as core technologies in a cascade/parallel approach. The biorefinery will be designed by a circular concept to maximize energy and mass integration, targeting zero-waste/carbon emissions production and minimum energy needs. For that aim, computational tools will be significant methodologies to support the design, modelling, optimization and scale-up of the bioprocesses. The process will be assessed in terms of environmental, techno-economic and social impact, considering the regional/local
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Programme de recherche sur les lacs collinaires dans la zone semi-aride du pourtour Méditerranéen'.

assistant: **Objectives**

The main objectives are as follows :* To study an optimal management of each type of hill reservoirs. The use of the supplement of water resource by users raises both technical and social questions such as, what is the duration of life of a reservoir (siltation) ? or what are the possible social organization of the users ?* To define an optimal land use planning upstream and downstream the artificial lake. To protect the reservoir, soil conservation works have to be planed on the slopes of the watershed. The development of lands close to the lake downstream (gravity irrigation) or on slopes (pumping requires adequate management. Fish breeding is a possibility to valorize the new water resource, just as the tourist exploitation of some sites.To assess the impact of one or several lakes on the environment. The hill reservoir is considered as an artificial structure of little size with very few impacts on the environment. This postulate has often occulted researches on real impacts and on ecosystems modifications.Expected OutcomeThe work carried out in this project should provide guidance for small and medium hydraulic works in soil and water conservation in semi-arid hill areas. It should identify natural and human constraints to the development of hill reservoirs and provide tools for assistance to decision makers at regional and national levels. It should also highlight the importance of small catchment areas in water resources mobilization particularly during dry periods. Starting from the Tunisian example, Hydromed will deepen the reflection on projects of small and medium hydraulic systems and transfer it to the totality of the semi-arid Mediterranean periphery.Hydromed contains four work packages, a training program and coordination activities. The four work package
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Borderline Personality Disorder: Memory and Identity in Adolescence'.

assistant: **Innovation**

BOLD MINDS aspires to enhance the understanding of vulnerability factors underlying the emergence of borderline personality disorder (BPD), with an ultimate aim of increasing the potential for young individuals to receive early, evidence-based help when their mental health is at risk. BOLD MINDS will achieve this by investigating whether disruptions in two aspects of autobiographical memory (AM), narrative identity (NI) and involuntary AM (IAM), are associated with BPD features and problem behaviours in adolescents concurrently and over time. In doing so, BOLD MINDS will strengthen the understanding of mechanisms underlying the emergence of BPD in adolescence and lay a groundwork for developing evidence-based early interventions for BPD. While currently limited, the study of AM in this field is essential for two reasons. Firstly, because the aspects of AM under investigation, NI and IAM, are known to be involved in identity formation and emotion regulation which represent two key psychological processes that are disrupted in adults with BPD and are linked to problem behaviours such as self-harm and suicidality. Secondly, because promising research is emerging on the use of AM targets in the treatment of emotional disorder in adults, and provides a strong model for future treatment development with vulnerable adolescents. In addition, this timely research program aligns with calls from international organizations to prioritize early interventions to promote adolescent mental health. BOLD MINDS will adopt and adapt state-of-the-art ecological momentary assessment and analytical techniques and work at the crossroads of clinical and cognitive psychological perspectives, allowing for a multidimensional approach to understanding BPD vulnerability. Training-through-research an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'A Universal platform for recycling plastic waste using dynamic covalent bonds' (ReBond) targeting Horizon Europe.

assistant: **Abstract**

Despite the ubiquity of plastics in daily life, our capacity to recycle end-of-life plastic products remains limited. Today, most plastic waste collected in the EU is either sent to landfill or incinerated for energy recovery, which releases large amounts of greenhouse gases. A promising strategy for transforming the plastics sector into a circular economy is to increase the amount of plastic waste that is mechanically recycled. However, this amount represents less than 10% of the feedstock used to make new products in the EU, because of poor physical properties. Three formidable challenges are at the origin of this lasting problem: chain degradation during processing, immiscibility of mixtures comprising different kinds of recycled polymers, and reduced ability to efficiently  recycle elastomeric materials with permanent bonds. We propose to address them with ReBond, a DN dedicated to developing a versatile platform for reinforcing polymer-polymer interfaces and improving the mechanical  properties and processability of recycled plastics. We shall implement a novel strategy based on the use of vitrimers, which are permanent chemical networks comprising thermally-activated dynamic covalent crosslinks. We envision that processing  of recycled polymers can be substantially enhanced through the addition of vitrimers. To accomplish this ambitious goal we have devised an interdisciplinary approach involving polymer synthesis, structure, rheology, processing and mechanical properties. A superb training program, spanning polymer chemistry, physics, and engineering, provides trainees with double doctorates and a unique scientific background with access to the state-of-the-art in the field. ReBond assembles an international team of experts from both academia and industry to prov
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Peptide-based Hydrogen Bonding Phase-Transfer Catalysis for Asymmetric Nucleophilic Fluorination', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Asymmetric nucleophilic fluorination remains one of the most challenging transformations in organic chemistry. In light of the importance of chiral fluorochemicals for the pharmaceutical sector, the development of innovative enantioselective fluorination methods with alkali metal fluoride is highly desirable. In this work, we propose to merge two conceptual manifolds, namely peptide-based organocatalysis and hydrogen bonding phase-transfer catalysis. We propose to investigate experimentally the binding ability of an extensive β-turn-based peptide library to fluoride, a fundamental unprecedented study. The insight into the binding profiles and conformational properties of these peptides will be essential for developing an asymmetric catalytic nucleophilic fluorination procedure. In this context, we shall first focus on synthesising pharmaceutically relevant cyclic β-fluoroamines. Subsequently, the peptide-catalyst design will be further refined by introducing a substrate binding region for targeting aryl amides, esters, thioesters, and sulfones. Upon completion, this work will provide medicinal chemists with a novel peptide-catalysed asymmetric nucleophilic fluorination reaction, an advance expanding the scope of organocatalytic nucleophilic fluorination reactions.


**Keywords:** asymmetric nucleophilic fluorination, organocatalysis, phase-transfer catalysis, peptide catalysis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'FREquency Security of Low-INertia electrical Grids' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The use of renewable energy has become the key to addressing the existential threats of climate change and environmental degradation to the world. Different from synchronous generators, the renewable resources are typically connected to the electrical grid via power electronic converters without inherent inertia. This transition brings new issues to the frequency security of such low-inertia systems, which are not yet fully understood. This project will investigate these issues with the emphasis on frequency dynamic modelling, its security assessment, and security-enhanced control design. Firstly, voltage-dependent frequency dynamics will be modelled for an electrical network simplified by Kron reduction. Next, the interactions between the resources and the electrical network will be analysed based on the developed frequency dynamic model. A key performance indicator will be developed with data-driven approaches and used to assess frequency security via the Lyapunov synthesis. Then, applicable distributed control strategies will be designed to enhance frequency security. This project will be carried out by me who has expertise in high-performance control designs for microgrids. Through this project, I will collaborate with my supervisor at Aalborg University who has a rich experience in low-inertia power system security analysis. Besides, I will also cooperate with my secondment supervisor at University College Dublin who is the pioneer in developing the frequency dynamic models. These collaborations will ensure both high-quality project outcomes and benefiting my career development. The project results will be disseminated through peer-reviewed journal articles and conference proceedings to expand their impact. Finally, communication activities with the public and acad