RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Enhancing fuel efficiency and reducing vehicle maintenance and downtime costs, using real-time data from vehicle sensors (IoT) and a machine learning algorithm for big data analysis.', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Jam is an IoT solution (hardware & software), aiming to improve the efficiency of businesses operating medium/heavy-duty vehicle (e.g. passenger and distribution fleets) and industrial fleets (e.g. mining trucks and agriculture vehicles), targeting key needs:- Fuel efficiency: fuel represented, in 2011, 32% of the total cost of fleet operation- Compliance with environmental regulations and reduction of GHG emissions- Vehicle off-road (VOR) time and maintenance costs: Many operators put the cost of having a single VOR as being in the hundreds, if not thousands, euros/dayAccording to Frost & Sullivan, the OBD market is expected to reach 117.8 million subscribers in 2019 and to become a billion-dollar industry by 2020. Although there are already solutions on the market for ECU interpretation on light-duty vehicles, the amount of new protocols, physical interfaces and differences in details in the way industrial vehicles operate constitute a barrier, not yet surpassed.Business and industrial fleets need an agnostic solution that allows optimizing the fleet management by reducing the maintenance costs and VOR time. Jam brings an innovative approach and focus on prevention and constant analysis of real-time vehicle data through a machine-learning algorithm allowing companies to save money on fuel costs, vehicle parts and hours of labour due to a more efficient management of fleet resources. Competitive advantages: - Designed for medium/heavy-duty and industrial vehicles - Agnostic system- Machine-learning algorithm that compares the ECU sensor data with historical data, predicting critical events- New eco-driving approach- Troubleshooting and scheduled repairs approach focused on prevention and constant analysis of real-time vehicle dataThe solution will be implemented at a g
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Adaptive ADAS to support incapacitated drivers Mitigate Effectively risks through tailor made HMI under automation' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

ADAS&ME (“Adaptive ADAS to support incapacitated drivers &Mitigate Effectively risks through tailor made HMI under automation”) will develop adapted Advanced Driver Assistance Systems, that incorporate driver/rider state, situational/environmental context, and adaptive interaction to automatically transfer control between vehicle and driver/rider and thus ensure safer and more efficient road usage. To achieve this, a holistic approach will be taken which considers automated driving along with information on driver/rider state. The work is based around 7 provisionally identified Use Cases for cars, trucks, buses and motorcycles, aiming to cover a large proportion of driving on European roads. Experimental research will be carried out on algorithms for driver state monitoring as well as on HMI and automation transitions. It will develop robust detection/prediction algorithms for driver/rider state monitoring towards different driver states, such as fatigue, sleepiness, stress, inattention and impairing emotions, employing existing and novel sensing technologies, taking into account traffic and weather conditions via V2X and personalizing them to individual driver’s physiology and driving behaviour. In addition, the core development includes multimodal and adaptive warning and intervention strategies based on current driver state and severity of scenarios. The final outcome is the successful fusion of the developed elements into an integrated driver/rider state monitoring system, able to both be utilized in and be supported by vehicle automation of Levels 1 to 4. The system will be validated with a wide pool of drivers/riders under simulated and real road conditions and under different driver/rider states; with the use of 2 cars (1 conventional, 1 electric), 1 truck, 2 PTW
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Ethical, Legal, and Social Aspects and Implications of Direct-to-Consumer Genetic Testing' (ELSAIDTCGT).

assistant: **Innovation**

With ongoing genetic discoveries and improvements in technology, more genetic tests are made available in a clinical context than ever before. Along with the increase in genetic tests offered there has been a recent rise in companies providing various genetic tests directly-to-consumers (DTC) bypassing the traditional face-to-face meeting with a health care professional. DTC genetic tests have generated various concerns with regard to tests’ analytical and clinical validity, as well as clinical utility; issues related to the quality of pre- and post-test counselling; and the lack of legal regulation. The overall objectives of this research project are to investigate the ethical, legal and social aspects and implications of the provision of genetic tests directly to consumers as is currently done by various companies. Five specific goals form the basis of this work: Firstly, a systematic and indepth review of the field of DTC companies will be performed using content analysis of company web sites. Secondly, this project aims to compare the existing regulatory framework of DTC genetic testing in Europe and North-America (US and Canada). Thirdly, the attitudes of European and North-American geneticists regarding the provision of direct-to-consumer genetic services will be surveyed and analyzed. Fourthly, as a case study of such services, companies offering tests for psychiatric diseases as well as the potential consequences of such services will be investigated. Finally, the last goal will be to disseminate the knowledge developed and to stimulate international and interdisciplinary collaboration by developing a website and organizing an international workshop, network, and conference. Dr. Heidi Howard, (Ph.D. Genetics 2003, MA Bioethics 2008) will, by her background in ge
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Exploration of safety, tolerability and clinical efficacy of Solnatide IMP in patients infected with the 2019 new coronavirus' under Horizon 2020.

assistant: **Concept**

Clinical features of patients infected with the 2019-nCoV have revealed that these patients suffer from severe respiratory failure, and presence of a life-threatening pulmonary oedema (PPO). Approx. 30% of 2019-nCoV-patients further develop life-threatening Acute Respiratory Distress Syndrome (ARDS). Mortality rate of these patients is very high.Initiator and Scientific Coordinator of the project, APEPTICO, is a SME biotechnology company (EMEA/SME/012/09) developing peptide-based products targeting life-threatening pulmonary diseases, including oedematous respiratory failure, acute lung injury, primary graft dysfunction, high altitude pulmonary oedema and PHA type 1.APEPTICO’s lead-compound Solnatide (INN) has been designed for the therapeutic treatment of patients with Acute Respiratory Distress Syndrome (ARDS) and various forms of life-threatening Pulmonary Oedema (PPO). Orally inhaled Solnatide has delivered clinical proof-of-concept in one Phase I, and in two Phase II clinical studies (EUDRACT No. 2011-000223-33, 2012-001863-64, 2013-000716-21).Today, no medicine has been approved for the therapeutic treatment of Pulmonary Permeability Oedema and ARDS.Currently, Solnatide is subject to a Phase IIB trial (EUDRACT No. 2017-003855-47) for the “treatment of pulmonary permeability oedema in patients with ARDS”. The Phase IIB clinical trial has been approved by the German and the Austrian Competent Authorities, as well by Ethic Committees of leading Medical University Hospitals in Germany as well Austria.Most recently, APEPTICO has entered into a partnership with HAISCO Pharmaceutical Group in Chengdu, Sichuan, P.R. China. HAISCO has access to core areas and leading Medical University Hospitals in the P.R. China.Accordingly, APEPTICO proposes to immediately apply the Soln
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Advancing organic SemicondUctor / 2D hybrid organic-inorganic PERovskite heterojunction-based floating-GATE transistors for neuromorphic computing applications'.

assistant: **Innovation**

The ascent of artificial intelligence and the increasing demand for clean energy technologies in Europe has given rise to a pertinent need for modern computing systems with reduced energy consumption. Neuromorphic computing, inspired by the working of the human brain, constitutes a potential paradigm shift in low-energy computing. Floating gate synaptic transistors (FGTs), critical components in neuromorphic computing hardware, offer promising pathways to perform massively parallel computational tasks with ultralow energy consumption of 1-10 fJ/spike. Despite the promises of FGTs, several challenges related to limited control over the charge-trapping properties, morphology, and stability of the floating gate layer need to be addressed. The SUPER-GATE project introduces an innovative concept of combining advanced 2D hybrid organic-inorganic perovskite (HOIP) molecular design with a facile and effective heterojunction design. In SUPER-GATE, an interdisciplinary strategy of materials and device engineering will be implemented by fine-tuning the energy level alignment of the organic cation in the 2D HOIP with an organic semiconductor channel in the form of a heterojunction. This will lead to synaptic performance with ultra-low power consumption (<1 fJ/spike) and more stable HOIP-based FGT devices than achieved to date (>152 days). Combining advanced optoelectronic and morphological characterization, structure-property-performance relationships will be formulated to guide further material and device development. The expertise of the researcher in the fabrication and optimization of organic electronic devices by solution-processed techniques will be combined with the host's experience in HOIP synthesis and the advanced optoelectronic characterization of transistors. The in-de
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'metasurface-Integrated Light Detection and Ranging' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

The “i-LiDAR” PoC project addresses the realisation of high-resolution and high-frame rate imaging systems. Relying on a combination of newly developed planar optical components, known as metasurfaces to achieve large deflection angles, with existing opto-mechanical systems, known for their high-speed light modulations, we will realize new light detection and ranging devices. The proof of concept devices are of great interests for both civil and military applications. Improving the scanning rate by orders of magnitude while preserving a continuous beam steering capabilities, could enable new high-speed applications. Fast imaging i-LiDAR system could be of interest for self-driven cars, giving them sufficiently fast ‘‘visual’’ recognition in order to adjust the driving conditions in real time, for example to drive on highways
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Scriptores Iuris Romani. Texts and Thought.'.

assistant: **Innovation**

The goal the PI intends to reach, in cooperation with scholars of the Universities of Roma 'La Sapienza', Pavia, Siena, Bologna, Cassino and others Italian and European Universities, is to create the basis – in texts and in interpretation - for a new approach to the remains of the ancient Roman jurists. What we suggest is an advanced paradigm in considering the most important part of Roman law: the Justinian Digesta, and other juridical Late antique anthologies. A change of perspective of great impact not only for the scholars in Antiquity, but also for a educated audience, interested in law and history. An historiographic model that will overturn current outlooks, making way for a different view, which seems to us of great interest today, both for legal and historical studies. No more the institutes, the norms and the rules of Roman Law –in the misleading form of the Code- but the effective legal thinking of its authors, the ancient iuris prudentes. Our aim is to focus the attention on their thought in the context of the time they belonged to. The achievement of the objective will be carried out through a reconstruction, and annotated edition, in several volumes, of the writings of jurists handed down in the Digesta and in other anthologies: an undertaking that has never been attempted. We will proceed by author and by work. A collection, entitled Scriptores iuris Romani (also available in e-book format) will gather the annotated editions. Each volume will consist of four parts (Introduction dedicated to the jurist considered and to his reconstructed work(s); Latin text (or Greek); Italian translation; commentary). The edition will be progressive and cover the entire period of the project.With regard to the choice of jurists to be edited, we will proceed by dealing wit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Standardization and Development of Assays for Assessment of Influenza Vaccines Correlates of Protection' (FLUCOP).

assistant: **Concept**

Background: Influenza viruses cause annual epidemic and occasional pandemics, both of which induce significant morbidity and mortality. Influenza infections affect all age groups but children and adults over the age of 65 are at most risk of developing severe disease.Vaccination is the most effective approach to reduce the impact of annual influenza outbreaks and potential pandemics, however, the currently criteria of correlates of protection(CoP) show limitations in predicting protection for seasonal and pandemic vaccines. The Haemagglutinin Inhibition(HAI) antibody titre is the most widely used CoP for seasonal influenza vaccine even if there is a lack of standardisation for conducting HAI and other serological assays and therefore  results obtained from different laboratories are not comparable. This leads to the urgent need of  improving international standardisation of serological assays to reduce inter laboratory variability and to generate supportive immunological assays to be used in studies aimed at developing clinically relevant surrogate markers of protection of influenza vaccines.Objectives: The main long-term aim of the FLUCOP project is to improve and standardize the existing immunological assays and to develop new assays for the better evaluation of the CoP of influenza vaccines.Main specific FLUCOP objectives include:-achieve standardization of HAI and Virus Neutralization(VN) assays;-promote the understanding and application of Cell-Mediated Immunity (CMI) and Neuraminidase (NA) assays as tools for the evaluation of influenza vaccines; -develop selective new assays which might potentially used for future clinical trials for influenza seasonal vaccine evaluationFLUCOP Consortium and Project Impact: The FLUCOP consortium brings together 26 groups from 7 E
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Glioma Actively Personalized Vaccine Consortium'.

assistant: **Innovation**

Glioblastoma (GBM) is a rare (2-3 incidences in 100,000) and fatal disease. Each year, approximately 13,000 new cases of GBM are diagnosed in Europe. The 5-year survival rate of this highly aggressive tumor entity under conventional therapy is less than 6%. Currently available therapeutic options neglect the individuality of each patients’ disease and only temporarily influence tumor progression with poor effect on overall survival. Introduction of novel highly innovative personalized approaches would have tremendous impacts for the life course of affected patients without additive toxicities.  Active cancer immunotherapy aims to trigger the patients´ immune system, specifically cytotoxic T lymphocytes (CTLs) and T helper cells, to defend the body against the cancerous disease. The Glioma Actively Personalized Vaccine Consortium (GAPVAC) aims to conduct a highly innovative pioneering project with active personalized immunotherapy to improve patient treatment. In a Phase I/II study at the center of this proposal, glioblastoma patients will receive a fully personalized peptide-based vaccine as a result of full-genome sequencing and complete peptidomics analysis of the patient’s tumor. Thus, the latest developments in next-generation sequencing, proteomics, immunology, biomarker research and small-scale GMP peptide manufacturing will be uniquely combined to deliver the next generation of  personalized medicine to cancer patients. GAPVAC’s goal is to test safety, feasibility and efficacy (biological and early clinical) of this totally novel, completely personalized approach of immunotherapy. GAPVAC is therefore specifically answering the call HEALTH.2012.1.2-1 Development of technologies with a view to patient group stratification for personalized medicine applications by a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Service Creation Engineering Environment' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Over a period of 30 months, the SCREEN project will develop an approach for service creation targeted to multivendored environments, supporting CORBA and TINA. The project, that was started in September 1996, aims to consolidate and extend existing and emerging technologies to produce a seamless tool-supported approach to component-based service creation. Field trials play a key role in exercising and demonstrating the project results in real service environments. The primary objectives of the project are:- to define and demonstrate service creation environments (SCEs) targeted to specific service architectures and to distributed processing environments (e.g. TINA, CORBA),- to demonstrate creation of services from reusable components,- to demonstrate the effectiveness of SCEs in treating quality of service (QoS) constraints and service interaction concerns,- to promote the use of SCEs by means of trials and documenting sound engineering practices for service creation.The project results are intended to:- cover a wide spectrum of services,- be applicable to a variety of business and technological contexts,- address the needs and profiles of a wide range of service providers.Expected Achievements - Documented sound engineering practices for component-based service creation targeted towards a TINA environment, addressing the needs of a multitude of users,- SCEs assembled from existing methods, techniques and tools, adapted where appropriate, to support a wide range of services including multimedia,- Practice and associated tools for component development, composition/decomposition, reuse and maintenance,- Shared component repository for use mainly by external trials and ACTS Service Architectures projects,- Results of the trials validating the assembled SCE and the enginee