RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The organofunctional chemistry of fullerenes' under Fourth Framework.

assistant: **Concept**

The project aims to develop the applicant's practical knowledge of fullerene chemistry which will enhance his understanding of the reactivity patterns of the cage and broaden his exposure to synthetic methods. The work is desirable at a time when fullerenes are under comprehensive examination world-wide. Training content (objective, benefit and expected impact) The main objectives of the project arise from a novel cycloaddition to the fullerene C60, discovered by the applicant. The resulting cycloadduct will act as a starting point for developing new functional chemistry of the cage and addends thereof and will usefully further our understanding of the chemical behaviour of fullerenes. Links with industry / industrial relevance (22) Fullerenes are already showing considerable promise as pharmaceuticals, semiconductors and as optoelectronic devices in which the cages are often deposited on surfaces. Existing links with Industry (BP and Zeneca) will be exploited so that all new compounds resulting from the project will be routinely tested for their potential under these headings.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Innovative Paper Packaging Products for European SMEs Based on Functional Modification of Recovered Fibres' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The project's objective is the creation of an innovative process based on modification of recovered fibres to be used to produce new functional packaging products with high level of standardization in EU, reducing the need of the sector for virgin fibres and supporting the competitiveness of the SMEs in EU packaging sector, through:- study and develop potential treatments for recovered fibre modification capable of improving physical- chemical properties of recycled papers- select the best fibre modification treatments based on property and recyclability criteria and validate at pilot plant scale- develop appropriate modification process systems of recovered fibres, explore new possibilities for both cost reduction and quality increase in packaging design and manufacturing with the input of all stakeholders- implement, demonstrate and validate a pilot plant for fibre modification (energy and raw material efficiency). The plant will be realized with the assistance of SME consortium members- train the staff of all the participants and disseminate the results to interested packaging SMEs (organize training courses and technical seminars, publish in practical sector journals and brochures and use internet)- identify new uses of enhanced modified fibre papers by comparing the state-of-the-art and the results of Fibre+ technology in corrugating packaging SMEs- foster the implementation of the new innovative fibre modification technology in SME users.It is foreseen that the project will serve to identify the industrial bottlenecks of paperboard SMEs and to establish a channel for them to express their interests and specifications for the new innovative modification process of recovered fibres with criteria of performance and optimisation. The consortium will create a database
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Computer science and information technology' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

This proposed aims to encourage and support the participation of researchers from NIS countries to the Computer Science and Information Technology CSIT'2002 workshop. It is a well known even throughout scientific community of NIS countries that ensures the great participation from these. The place of the event increases the participation of scientists from EU. This workshop brings together the majority of researchers who work in the area of Computer Science in the NIS countries. It will host a variety of contributed, invited and plenary papers. It facilitate researchers from EU and NIS countries to present, discuss and further develop views on the specific scientific area and develop a network for further scientific collaboration. The key intention is to create a forum where scientists from every edge of Europe will discuss, and where theories and techniques can be debated in detail, as well as to facilitate the exchange of their experiences.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'AIP gene regulation and its implications in pituitary tumorigenesis' (REGAIP).

assistant: **Concept**

Background: Pituitary adenomas are a public health problem, due to their prevalence, morbidity and medical costs. AIP is a tumor suppressor gene that was recently linked to pituitary tumors in up to 30% of the familial isolated pituitary adenoma syndrome (FIPA) families, an autosomal dominant disease with incomplete penetrance. AIP mutation-positive patients are younger (children/young adults), have more aggressive disease, and respond less well to treatment than non-mutated patients. The mechanisms by which inactivating AIP mutations promote tumorigenesis remain unknown. Abnormal, mislocalised AIP expression in sporadic pituitary adenomas suggest a possible role in sporadic pituitary adenoma development as well. Very little is known about the normal and pathological regulation of AIP expression.Objective: To uncover major AIP transcription regulation by its canonical promoter, miRNA species and epistatic action of distant regulatory SNPs (eQTLs).Methods: 1) In vitro functional promoter dissection and identification of operating transcription factors and investigation of promoter mutations in FIPA families.2) Screening and validation of miRNA species acting on AIP and study of their expression in pituitary adenomas and correlation with clinical / pathological features.3) Detection and validation of AIP eQTLs and study of their implication in AIP mutation penetrance and their association with sporadic pituitary adenomas and their clinical/pathological features.Work programme relevance: Training through research in a major European pituitary centre will ensure development of essential experimental, theoretical and organizational skills of the fellow and will advance research at the host institution, thus improving quality of research at the ERA. The research results will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Algorithms for radio network optimisation' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

The main aim of ARNO is to develop optimisation methods and associated software tools for cellular network engineering.Up to now the combinatorial complexity of cellular network design has not been considered by the exploitation services of mobile operators as a main optimisation problem to computerise. Essential optimisation procedures involved only the handmade parametrisation of current networks. However, now the rapid growth of network size and design complexity make essential to consider the combinatorial complexity of network design as an optimisation problem in need of computerisation. From an optimisation point of view, it means dealing with the interconnection of subproblems, an enormous volume of data, and difficult combinatorial aspects, features which cannot be taken into account optimally without advanced computerisation.Exploitable results from the project will consist of software tools incorporating optimisation algorithms. For existing networks a global optimisation procedure will allow optimised network extensions (i.e. additional sites and further frequency plans), and for new networks (micro-cellular technology and foreign markets) it will immediately ensure an optimised design. The software optimisation tools, which will be the exploitable results of ARNO, will not be restricted to the GSM networks. GSM characteristics will be used as a reference for the project, but the optimisation algorithms should be easily adjusted to manage network design with other systems (CDMA) and GSM future extension. It ensures to the project results which enable future developments to be included in the design of mobile networks.Cellular design scenarios are so varied that the robustness of algorithms constitutes a real problem: it prevents the consortium from studying o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Ergonomic research of office workstations: better design criteria and optimal matching of the man-machine system for visual display work' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The ergonomic quality of office furniture and equipment used in practice can be improved significantly. This helps in increasing comfort, productivity and in the prevention of health problems. The 'finding' of good equipment is a problem due to two main aspects: there is a confusingly large amount of technical documents, standards from the ergonomic point of view (EN 9241), and from the furniture point of view (prEN 1335, prEN 527, ...), as well as legal documents as the Council Directive 90/270/EEC. On the other hand, the variety of human factors that has to be accounted for, like type of task performed, anthropometrics aspects, mobility, etc, is large and is not logically covered by the documents mentioned above. Research is need to find out the origin of the office worker problems, to classify the great variety of tasks performed and individual needs and to generate design criteria and rules to manufacture and prescribe the right equipment to each group of users, taking into account the standard and legal documents. With these rules, an advisor system" is going to be implemented. Aimed at facilitate to the purchaser the certainty of the fulfilling of the requirements, it is foreseen to create a QUALITY LABEL."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'European NETwork of centres of excellence: digital CULTURE research and education network'.

assistant: **Concept**

This project is a preparatory action for E-Culture Net. A consortium of at least 24 members from 15 countries, 6 existing networks and links with 2 networks abroad, has been formed to evolve into a Network of Centres of Excellence (NCE) in the 6thFP. The project will refine the vision and structure; explore expansion and links with emerging national and other networks. It will identify/define research topics; how teaching can focus those topics; how broadband pilots can generate new research topics among partners and lay the foundation for a Distributed European Electronic Resource (DEER) for research and higher education.Objectives:The objective is to develop research roadmaps and implementation models to prepare for future RTD activities. The goal is to create a research framework, that will address especially the knowledge life-cycle applied to advanced digital libraries, culture and arts and extends to all five of the fields in the call. The project will explore how existing specialized networks, emerging national networks and the new consortium can be structured and expanded to evolve into a network in the 6th FP to achieve a European Research Area (ERA) in digital culture within the E-Europe vision. The emerging network will identify/define research topics; how an outline for an European Masters can focus those topics; how pilot broadband content from research results (IST, FET), can be used to generate new research question and lay the foundation for a Distributed European Electronic Resource (DEER) using JISC's DNER as a model.Work description:The consortium consists of 1 co-ordinator, 7 partners and 16 members, 6 networks within Europe, and two networks outside Europe (Canada, Japan) (Appendix 1). There are preliminary steps towards national networks in 5 count
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'The dynamics of sea ice variability – role of the oceans'.

assistant: **Concept**

Arctic sea-ice extent and volume are declining rapidly, and according to model simulations, the Arctic Ocean may become seasonally ice-free as early as around 2040. As sea ice is a critical component of the Earth system, for the prediction of future climatic processes and related environmental changes, it is crucial to forecast its evolution. However, despite the extreme societal and environmental relevance, our understanding of natural sea-ice variability and its response to external natural and human-induced forcing is associated with significant uncertainties. Consequently, state-of-the-art climate models still show a very large spread in the prediction of climate responses for the next century, especially at high latitudes. The insufficient knowledge about natural sea-ice states makes it essential to develop high-resolution sea-ice reconstructions extending back in time beyond the instrumental and satellite era. With this project I will thus improve our basic understanding of the processes determining Arctic sea-ice cover and variability by establishing multidecadal to millennial-scale time series of sea ice and general oceanic conditions on the North East Greenland shelf during the Holocene, with primary focus on the last few millenia. I will develop a high-resolution, multi-proxy reconstruction and link it to the Greenland ice-sheet dynamics, ocean circulation and global climate. I will define the pre-industrial baseline of Greenland sea-ice cover and test the link between sea ice and natural and human-induced climate forcings. Results from this project will have important implications not just for the community of palaeo-scientists but will provide crucial research-data for modellers in order to improve predictive climate models. Such improved models are critical
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Parallel Orthographic Processing and Reading'.

assistant: **Innovation**

The project centers on a new computational model, the POP-R model, that implements two original, and apparently contradictory, hypotheses with respect to the processing of orthographic information spanning several words during silent reading for meaning: 1) orthographic information spanning several words is processed in parallel and integrated within a single pool of location-invariant orthographic representations; 2) readers process multiple word identities in parallel and keep track of the positions of these words by associating word identities with spatiotopic locations in short-term memory. The apparent contradiction is solved in POP-R by the triangular connectivity between gaze-centered letter detectors, spatiotopic word identities, and location-invariant orthographic representations. Evidence in favor of the first hypothesis has been obtained with a novel Flanking Letters Lexical Decision task. The second hypothesis predicted the existence of a sentence superiority effect in a novel Rapid Parallel Visual Presentation paradigm, for which we have preliminary evidence. Other key predictions of the POP-R model will be tested in behavioral experiments using these new techniques, and EEG and MEG recordings will be used to specify the spatio-temporal dynamics of the neural processes underlying orthographic pooling and parallel word identification. Experiments with primary school children will plot the developmental trajectory of these processes, and sentence reading experiments measuring eye-movements and ERPs will be used to further test the model. The project incorporates both theoretical and methodological innovation within a novel perspective on reading that places orthographic processing at the very heart of the reading network. This new perspective is expected to f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'BET Proteins in Early Life Stress-induced Cardiovascular Disease' (BETonSTRESS).

assistant: **Concept**

Early life stress (ELS) in childhood due to physical or sexual violence, parental neglect, or trauma has been recently associated with an increased risk of cardiovascular disease in later life. However, the mechanisms linking ELS to cardiovascular impairment remain unexplored. Epigenetic regulation of gene expression is emerging as a pivotal process linking environmental exposure to disease phenotypes. Among chromatin remodelers, BET (bromodomain and extra-terminal) proteins are key regulators of gene transcription through their binding to acetylated lysine residues on histone tails via tandem bromodomains. Own preliminary data suggest that BET proteins are heavily involved in transcriptional programs relevant to cardiovascular disease. In BETonSTRESS, I hypothesize that childhood adversities alter the epigenetic landscape thus leading to maladaptive transcriptional programs and cardiovascular disease development. Using a mouse model of ELS and longitudinal cohorts, I will: i) investigate the chromatin landscape, BET function and cell-specific transcriptional changes in the ELS mouse heart; ii) test the effects of BET editing on cardiovascular function in ELS mice; iii) study the impact of stress-mitigating strategies (environmental enrichment) in preventing chromatin remodeling, BET activation and cardiac dysfunction in ELS mice; iv) test the cardiovascular predictive value of BET-related circulating biomarkers in two longitudinal cohorts of ELS-exposed individuals. The preliminary data suggest a prominent role of BET proteins in epigenetic remodeling and cardiac dysfunction in ELS mice.BETonSTRESS will: i) unveil the role of BET proteins and chromatin remodeling in ELS-induced cardiovascular dysfunction; ii) set the stage for stress-mitigating approaches and epigeneti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Bringing added value to agriculture and forest sectors by closing the research and innovation divide' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

AGRIFORVALOR will close the research and innovation divide by connecting practitioners from agriculture and forestry to research and academia  as well as with associations and clusters, bio -industry, policy makers; business support organisations, innovation agencies and technology transfer intermediaries in multi-actor innovation partnership networks. Theses networks will be managed by three Biomass Innovation Design Hubs, piloted in Andalucia, Hungary and Ireland.  In each of these hubs, existing research results and good practices on valorization of biomass sidestreams from agro and forest will be shared and matched with the specific needs and potentials; new grass-roots ideas collected and developed; and dedicated innovation support applied to further deploy selected topics which are dealt with by multi-actor innovation partnership groups. Here, practical support in the exploitation of promising research results is complemented by assistance in business (model) development - with a tailored mix of innovation support measures offered to individual subjects. Tailor-made innovation support tools and materials will thus be developed in line with the identified needs of forestry and agriculture. In each hub, Steering Committees consisting of experts on exploitation and business development will be set-up to monitor and consult the conceptualization and implementation of the trainings and support measures. Project results and experiences will be translated into recommendations for a more demand-driven research agenda as well as long-term end-user materials to feed into the EIP-AGRI. AGRIFORVALOR thus delivers as mediator and facilitator new commercial opportunities for the agriculture and forest sector in Europe to become active partner in the sidestream biomass value cha