RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Immune checkpoint blockade for fighting Alzheimer’s disease' (ImmuneCheckpointsAD).

assistant: **Innovation**

Understanding, and ultimately treating Alzheimer’s disease (AD) is a major need in Western countries. Currently, there is no available treatment to modify the disease. Several pioneering discoveries made by my team, attributing a key role to systemic immunity in brain maintenance and repair, and identifying unique interface between the brain’s borders through which the immune system assists the brain, led us to our recent discovery that transient reduction of systemic immune suppression could modify disease pathology, and reverse cognitive loss in mouse models of AD (Nature Communications, 2015; Nature Medicine, 2016; Science, 2014). This discovery emphasizes that AD is not restricted to the brain, but is associated with systemic immune dysfunction. Thus, the goal of addressing numerous risk factors that go awry in the AD brain, many of which are -as yet- unknown, could be accomplished by immunotherapy, using immune checkpoint blockade directed at the Programmed-death (PD)-1 pathway, to empower the immune system. In this proposal, we will adopt our new experimental paradigm to discover mechanisms through which the immune system supports the brain, and to identify key/novel molecular and cellular processes at various stages of the disease that are responsible for cognitive decline long before neurons are lost, and whose reversal or modification is needed to mitigate AD pathology, and prevent cognitive loss. Achieving our goals requires the multidisciplinary approaches and expertise at our disposal, including state-of-the art immunological, cellular, molecular, and genomic tools. The results will pave the way for developing a novel next-generation immunotherapy, by targeting additional selective immune checkpoint pathways, or identifying a specific immune-based therapeuti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Initiating paradigm shift towards sustainable cement production. Novel smart nano-additive reducing cement production carbon footprint, cost and energy demand.' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

Concrete is the most consumed manufactured substance on the planet. Concrete is affordable, strong, durable and resilient to fire, floods and pests. In fact, there is no other material currently available in the quantities necessary to meet the demand for buildings and infrastructure. Concrete is therefore today irreplaceable, and cement works as the glue that binds the concrete’s aggregates together.However, cement also has a massive carbon footprint. The chemical process of making cement emits staggeringly high levels of CO2 being the source of 8% of the world's CO2 emissions. The biggest challenge and opportunity lie in tweaking the recipe for cement in order to establish a much more environmentally friendly manufacturing process.Our ngCon additive innovation allows to formulate new classes of sustainable cements capable of tuning the bulk physical properties of concrete during preparation while improving its performance. First, ngCon additive offers a game-changing innovation in the cement production by reducing the calcination temperature from 1400°C to 800°C, hence cutting energy demand by 50%. ngCon also reduces the amount of calcium carbonate (CaCO3) required by 30%, which is the major responsible for the CO2 emissions after combustion. Second, ngCon additive drastically improves the compressive strength of concrete up to 50%. Whether it is for drying time, hardness or uniformity, the innovative ngCon additive developed by Nanogence can give to the construction material the desired consistency, all in one shot. As the cement industry is responsible for 8% of the world’s CO2 emissions, ngCon is addressing these two critical challenges, helping the sector to improve performance while meeting environmental legislations.Thanks to a scalable business case and through
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Alchemical Manuscripts in Medical Vienna, 14th-17th century' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

In the late medieval and early modern period, most learned men were fascinated with natural philosophy, the inquiry into the workings of nature. Vienna was among the key places in Central Europe where inquisitive minds met to practice a nature- or medicine-related profession. With its central position in continental Europe, its natural resources (including a long-standing mining tradition) and university, Vienna was also a prime location for alchemical and medical discovery, and many Austrian noblemen investigated the possibility of reviving a faltering economy with the help of alchemists. Medical doctors in and beyond the University of Vienna showed an interest in the use of alchemically produced remedies at various points in history, which eventually resulted in the development of pharmacy as we know it today. Alchemy was a craft and theoretical system that was as ubiquitous as it was debated. However, the history of medico-alchemical Vienna (and hence, Central Europe) written to date is far from complete, and shows one crucial oversight: the Viennese collections of alchemical manuscripts dating from the 14th to the 17th century have not been studied in detail by historians of science at all. This project is going to amend this situation by writing the history of alchemical inquiry and its intersections with medicine in Austria on the basis of Viennese manuscript materials. The project will be undertaken by Anke Timmermann, a young alchemical historian currently active in Philadelphia, USA. She will be working in the environment of the Medical University of Vienna, within the program section entitled “The collections of the Medical University of Vienna”, and utilize its collections of early printed books as reference points for the investigation of the alchemical manu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Multifunctional Digital Materials Platform for Smart Integrated Applications' (DIGISMART).

assistant: **Innovation**

DIGISMART creates new avenues into two main areas: 1) processing nanomaterials/nanostructures applied to electronic devices by exploring a new digital multifunctional direct laser writing (LDW) method for in situ synthesis of small-sized nanomaterials/nanofilms micro-patterned growth by selective photothermal decomposition of semiconductors, dielectrics and conductors precursors and 2) provide simultaneously multifunction to single based metal oxide devices (like thin film transistors, the workhorses for large area electronics having electron, charge and color modulation), as the basic unit to promote systems’ integration by exploring the use of new advanced materials with unique multi-functionalities using low cost process solutions. This new fabrication process will be very useful for low-cost, eco-friendly, and efficient fabrication of nanostructures and thin films-integrated microelectronic devices due to its low-power, simple setup as well as excellent reliability. This new and disruptive concept will be achieved with low cost and non-toxic materials (new metal oxides, MO semiconductors, conductors, dielectrics and electrochromics free of In and Ga) associated to a low cost process multifunctional platform technology (ALL-IN-ONE TOOL) well supported by high-resolution nano-characterization techniques. With DIGISMART new and unexplored materials will be produced as well as to boost the original properties of conventional materials in order to contribute to the needs for low cost and flexible electronics. If we succeed to embed some level of intelligence in every object, this would change electronics and it would change society, ranging from embedded window displays to a wide range of biomedical electronics, just to mention a few and this is what the Internet of Thin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on '"Chips on the go"": towards truly wearable EEG systems""'.

assistant: **Innovation**

Epilepsy affects about 50 million people. Routine electroencephalography (EEG) tests are not long enough to properly diagnose these patients. Long time in-patient monitoring is possible but costly for health organizations and removes the patient from his natural environment. Ambulatory EEG is an alternative but existing ambulatory systems are still too bulky and unaesthetic to wear while carrying out normal life. A truly wearable EEG system (WEEG) would: a) have the capability of monitoring for long periods of time; b) not present redundant data sections to the doctor hence reducing the interpretation time; c) be aesthetically discreet for the user; d) be comfortable to wear. Sleep disorders affect approximately 6% of the population. WEEG is still a necessary technology for the diagnosis and continuous monitoring of sleep disorders without the sufferer having to stay in hospital overnight. WEEG systems could also be used for early detection of drowsiness and prevention of road accidents. This project aims to tackle some of the most important technological challenges standing in the way of future electroencephalography (EEG) systems. Specifically, this research will focus on the microelectronic related issues of: a) reducing power to enable long term monitoring; b) reducing the size of EEG systems; c) reducing the amount of specialist time required to interpret the signals. These are key stepping stones for achievement of a truly wearable ambulatory EEG system (WEEG). Simultaneously this will advance knowledge of the practical limitations of different circuit design techniques which will now be used with specifications that largely differ from any other application for which they were used before.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'SUffix trees meet REgular languages' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

The SURE project (SUffix trees meet REgular languages) is an interdisciplinary project at the intersection of several areas: Algorithms, Data Compression, Automata Theory and Bioinformatics. Its primary objective is to extend the suffix tree, the most important data structure for string processing, to labeled graphs and automata, and to use this new paradigm for studying regular languages.The suffix tree of a string supports a myriad of natural queries on strings, including multiple pattern matching variants. Suffix trees inspired a variety of related data structures for string algorithms, such as the suffix array, the Burrows-Wheeler transform and the FM-index.Today’s world demands the processing and analysis of increasingly complex, interrelated data. All these relationships can be captured by using (labeled) graphs. For example, the World Wide Web can be modeled as a graph, where elements are connected through hyperlinks. Graphs are also widely used to model social networks and to create databases. The SURE project will lead to a new data structure, the suffix tree of a graph, efficiently supporting all previous queries on graphs. This will be crucial in the emerging field of pangenomics, where graphs can store multiple genomes, overcoming the inherent bias of a single reference genome.Graphs provide a natural framework for analyzing regular languages in automata theory. Recent results indicate that several string-processing data structures suggest a new paradigm for analyzing regular languages. The SURE project will extend this paradigm through the suffix tree of a graph, proving that the same ideas can be applied to other formalisms (such as omega-regular languages). We will also show how to study the hierarchy of regular languages induced by these data structures
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Public–Private Insurance Partnerships for Adapting to Multi-Hazard Climate Change Risks' (INSUREADAPT) targeting Horizon Europe.

assistant: **Abstract**

Natural disasters cause substantial economic losses, which are expected to increase due to climate change. The insurance sector plays a central role in managing these risks. It is thus imperative that insurers accurately assess and address climate risks. Risk assessment methods currently fall short in accurately understanding climate risks because they focus on single hazards (e.g. floods) instead of correlated multi-hazard risks (e.g. windstorms and floods) affected by climate change. They also insufficiently account for human climate adaptation processes leading to risk reduction, which are characterized by bounded rationality and social interaction. Furthermore, additional insights are needed into how to design insurance arrangements that address climate change and stimulate policyholders to adapt to multi-hazard climate risks by limiting natural disaster damage.This project aims to design insurance arrangements to enhance policyholders adaptation to multi-hazard climate risks by combining financial coverage with comprehensive strategies for stimulating risk reduction. Its interdisciplinary approach goes beyond the state-of-the-art by creating novel multi-hazard climate risk assessments for insurance and by developing agent-based models (ABMs) that account for boundedly rational human adaptation decisions and social interaction. The ABMs evaluate natural disaster insurance arrangements for EU countries with diverse risk contexts and assess strategies for stimulating adaptation by policyholders, based on input from behavioural economic studies. Repeated and real-time surveys and economic experiments will identify comprehensive strategies for triggering behavioural change to stimulate adaptation to the multitude of climate change risks individuals face. These strategie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Acquiring extremely high resolution maps of water use efficiency of Australian forests to assess the effects of drought, species composition and stand structure' to be submitted under Seventh Framework.

assistant: **Abstract**

Instantaneous ecosystem water use efficiency (WUE), the ratio of gross primary production (GPP) to evapotranspiration (ET), is an important integral trait of plant and ecosystem productivity and a key variable for modelling and understanding the impact of climate change on terrestrial ecosystems. Unfortunately, the influence of climate change on ecosystem WUE is difficult to predict, because the underlying mechanisms that cause variation in ecosystem WUE are largely unknown. A major limitation so far in the research on ecosystem WUE is the current impossibility to measure WUE at sub-ecosystem (ie single tree or plant) level.The aim of this research proposal is to generate ET, GPP and WUE maps of extremely high resolution of three Australian forest biomes. The remote sensing imagery needed for this will be acquired by applying an unmanned aerial vehicle (UAV), equipped with thermal, visual and near infrared cameras. These maps will allow us to investigate how the ET, GPP and WUE of single plants and of entire ecosystems is affected by drought, and how species composition and vegetation structure affect this relation.Two innovative new algorithms to estimate ET and GPP will be developed. These algorithms benefit from two key advantages that UAV-remote sensing offers, namely the unprecedented spatial resolution and the possibility to construct highly precise 3D maps of the canopy, thanks to the large image overlap. Measurements will be performed in three representative Australian forests, which will be monitored regularly during an entire year. Spatial and temporal analyses will be performed to assess the influence of stand structure and species contribution on GPP, ET and WUE and how these factors evolve in time, particularly during drought periods.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Embodied Imamate: Mapping the Development of the Early Shiʿi Community 700-900 CE' (ImBod) under Horizon Europe.

assistant: **Objectives**

The Shii Imams played a key role in early Islam. Revered scholars descended from the Prophet Muammad, they posed an existential threat to the legitimacy of the ruling caliphs in the 8th and 9th century CE. Their leadership defined the quietist yet oppositional Imami Shii community scattered throughout the Islamic empire. Imami Shiism was a key part of the turbulent thesis and antithesis which formed Islam, and it remains greatly influential until today. Remarkably, there is no comprehensive history of the Imamate. There are a number of reasons for this, central among which are that scholarship on Imami Shiism has approached it as a doctrinal and intellectual phenomenon. However, religious groups are also fundamentally social phenomena. ImBod will result in the first comprehensive history of the Shii Imamate. It will position the Imamate as a social phenomenon, framing it as an interaction between two aspects which are rarely explicitly theorised: the Imams, and the Imami community who recognised them. ImBod will identify and study the key spheres in which the Imams and the Imami community operated, including the Imams household, elite Arab clans (especially the Prophets family and the dynasties of the caliphs), the network of Imamic agents, the scholars, and the communities who came to be associated with Shii Islam through kinship, conversion and migration. ImBod will map out overlapping networks of interaction across these spheres and identify key actors and institutions responsible for mediating and performing the Imamate in the community. ImBod will not conceive of the Imamate as an essence, but as a set of social processes, some, but not all, instigated and controlled by the Imams themselves. Crucially, ImBod will study these processes as performed spatially and emb
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Modelling of VOCs in heritage collections using CFD' (SMELL-MODEL), addressing dissemination and exploitation.

assistant: **Impact**

The necessity to improve indoor air quality (IAQ) is widely recognized in view of its health implications and damage concerns to heritage. Volatile Organic Compounds (VOCs), constituting the typical ‘smell’ of museums, galleries, libraries and archives, have been shown to have an important role on the degradation of contemporary materials, but the real impact of artworks on IAQ is almost unknown. This is mainly due to the lack of knowledge of the behaviour of materials and objects as sources and sinks of these compounds in primary or secondary ways. The SmellModel project will focus on VOC reaction processes in order to improve indoor monitoring practices and prevent damage to cultural properties. The innovative challenge is to assess the issue of the impact of VOCs on heritage collections using the computational fluid dynamics (CFD) modelling tool. This objective is at the forefront of research in indoor air quality but has not been addressed at all yet.The principal aim of the project is to establish methods and models to predict interactions and provide reliable estimations of VOCs in different environmental conditions. Laboratory experiments as well as measurements in situ, i.e. in historic collections, will contribute to validation of the models and develop the understanding of how the concentration of VOCs varies as a function of material type (e.g. paper, carpet, wood), material properties (e.g. porosity, chemical composition), environmental physical quantities (e.g. temperature, relative humidity, air speed) and enclosure geometry or size (e.g. room, box, display case).A VOC database will be developed and used in a CFD platform that will allow prediction of VOCs in heritage environments. In this way the SmellModel project will enable forecasting of possible scen