RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'ROS AND AUXIN CROSSTALK DURING PLANT DEVELOPMENT AND STRESS ADAPTATION'.

assistant: **Concept**

Environmental cues represent the major hardships to crop productivity worldwide. Therefore, elucidation of plant stress adaptation networks has become a main biotechnology research objective. Auxin and its distribution rates play key roles in many aspects of plant growth and development, which largely depend on the spatiotemporal control of auxin homeostasis. Upon stress, increased reactive oxygen species (ROS) production affects auxin homeostasis and can lead to a reorientation of growth as part of the stress induced morphogenetic responses (SIMR). Conversely, auxin can trigger a programmed and cell-specific ROS generation to signal developmental and stress responses. There are now clear research evidences that reciprocal interaction between ROS and auxin signalling pathways are the main players of the SIMR, which modulate plant growth and development to attenuate deleterious effects of stress. On the other hand, environmental factors primary affect photosynthesis, compromising plant growth and yield. Basically, photosynthesis acts as global stress sensors activating photosynthesis adaptation and stress responses, which directly affect ROS and auxin homeostasis. Notwithstanding the large number of evidence showing interplay between ROS and auxin on photosynthesis, research on this topic has not been addressed and much of the work that has been done centres on ROS-auxin crosstalk in heterotrophic tissues. Although ROS-auxin interplay is being intensively studied, the mechanisms underlying their crosstalk are poorly understood. In this respect, molecular insight into the nature of ROS-auxin crosstalk remains scarce. The project aims to decipher how environmental and developmental signals are integrated by ROS-auxin crosstalk and to unravel the underlying mechanisms that
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Development capacity index for biotech companies'.

assistant: **Innovation**

This project will develop a Development capacity Index" (DCI) for biotech companies in the New Member States, highlighting the growth potential of healthcare biotech. Data collected will be comparable from country to country and be benchmarked against existing data from the EU-15. A set of policy recommendations will accompany the DCI which will illustrate where fruitful collaborations might arise, where the intervention of policy makers and private capital might most usefully be deployed.Insights into country's relative strengths and weaknesses can provide policy responses to questions like:- To what extend does targeted national government support help companies perform better?- How much money can the average Slovenian company raise in years 0-7 compared to their UK, or Swedish counterparts?- If a company moves products into phase I, is it attracting Venture Capitalists (VCs) into phase II?- Who are the new Member States elite companies and do they compete with other European elites?"
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Biomechanics of menisci: a multiscale experimental, theoretical and modelling approach for biomimetic meniscal replacements' (MetaBioMec).

assistant: **Innovation**

The meniscus plays a critical role in load transmission, stability and energy dissipation in the knee joint. Loss of the meniscus leads to joint degeneration and osteoarthritis. In a number of cases  replacement of the resected meniscal tissue by a synthetic implant might avoid the articular cartilage degeneration. None of the available implants presents optimal biomechanics characteristic due to the fact the biomechanics functionality of the meniscus is not yet fully understood.  Mimicking the native biomechanical characteristics of the menisci seems to be the key factor in meniscus replacement functioning. This is extremely challenging due to its complex inhomogeneous microstructure, the lack of a full experimental characterization of the material properties and the lack of 3D theoretical, numerical and computational models which can reproduce and validate the experimental results.  Therefore, the aim of this work is a thorough understanding of the menisci biomechanics with the view of translating the knowlege to the orthopeadic implants arena. The objective of the proposal be achieved through (i) designing and performing a range of innovative experimental tests to characterize the behaviour of the meniscus tissue at the micro and macroscale, (ii) building an appropriate and novel multiscale anisotropic model at the tissue level which takes into account the fractal dimension of the porous menisci’s tissue, (iii) implementing the material model in commercial finite element (FE) software and (vi) build and validate an accurate FE biomechanical model of the knee joint (which includes the meniscus) in order to model the biomechanical behaviour of the menisci when subjected to a range of mechanical stress which is not reproducible in an experimental context.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Automated Crowd Simulation with Artificial Intelligence' to be submitted under Horizon Europe.

assistant: **Abstract**

With the transformation of transportation from individual to public transport and the new climate goals of the European Green Deal, public transportation faces major challenges in the coming years. The number of passengers is expected to more than double. Stations must be quickly expanded to accommodate the increasing number of passengers. Remodeling existing stations is more complex than building new ones, is error prone and quickly lead to costs and time explosions.New methods, technologies, and processes are needed to solve this. Our project Automated Crowd Simulation with Artificial Intelligence (ACSAI) focuses on exploring and combining existing deep tech solutions into a new one. BIM in combination with crowd simulation enables planners to digitally prototype buildings at early planning stages to prevent costly mistakes. Although BIM speeds the process of data preparation, a high computational effort is needed for the execution. As a result, only a few design variants or scenarios can be analysed as of today.To overcome this issue, we combine simulation models with machine learning methods: AI Models shall be developed and trained with the help of precalculated simulation data. The trained NN can give answers at the push of a button, whether a design is compliant or not. This accelerates the process enormously since it quickly sorts out designs that are not feasible. Thus, only pre-checked design variants will be simulated for final confirmation and optimisation. The whole approach is a quantum leap in the planning process since it speeds it up and reduces the risk of planning mistakes enormously.We have tested the approach for railway stations in a PoC environment in the research project BEYOND. The next step is to implement it in our crowd simulation software in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Polymer brushes - a sustainable bonding technology for dissimilar materials' to be submitted under Horizon 2020.

assistant: **Abstract**

Technological developments are moving ever faster in our modern society, and so are the pressure put on industries to produce safe and sustainable products within a circular economy perspective. Hybrid assemblies, joints of dissimilar materials, are key in modern product design and found everywhere - in your smartphone, car, TV, dishwasher, in planes and so on. However, in modern products we increasingly rely on engineering plastics and fiber-reinforced plastic composites, which is intrinsically hard to bond to other types of material - and using industrial glue you cannot easily recycle the plastic part. This has become a major challenge that hampers development of better, more durable, longer living, and sustainable products in key manufacturing industries such as automotive, aerospace, medical device, electronics, renewables, offshore, consumer goods, etc. A prime example is the slow adoption of the most potent lightweight materials, high-performance plastics and plastic composites (70% weight reduction potential), in the transportation industry due to lack of acceptable joining methods – severely limiting the CO2 reduction potential of new cars and planes. RadiSurf has developed the groundbreaking RadiBond technology, based on nanometer-thin coatings of polymer brushes, that provide sustainable, ultra-strong and ultra-tight hybrid joints that can easily be reversed at product end-of-life for disassembly and recycling of the bonded parts. RadiBond is a key enabling technology bringing outstanding bonding performance and easy integration into existing manufacturing assembly lines. As the pioneer in the industrial utilization of polymer brushes, Radisurf are now targeting full-scale market launch of RadiBond. However, to succeed in the transition from a small R&D provi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Development of Narrow Band Blue and Red Emitting Macromolecules for Solution-Processed Solid State Lighting Devices' (NarrowbandSSL) targeting Horizon 2020.

assistant: **Abstract**

This project targets the development of solution-processable narrow-band thermally activated delayed fluorescence compounds that will be employed in low-cost solution-processed solid-state lighting devices. Solution-processed organic light-emitting diodes (OLEDs) and light emitting electrochemical cells (LECs) will be fabricated from these materials. The stringent design criteria will be met by adapting multi-resonant thermally activated delayed fluorescence materials to be compatible with solution processing techniques. Using the proposed design it is expected that narrow emission (FWHM of 25-30 nm) and high efficiency can be maintained, which would represent a real advance in both solution-processed OLEDs and LECs. This project will specifically develop solution-processable blue and red narrow band emitting TADF materials as these are both essential for displays and lighting and whose performance in current state-of-the-art OLEDs and LECs remains sub-optimal.


**Keywords:** Organic light emitting diodes (OLEDs), Light emitting electrochemical cells (LECs), Thermally activated delayed fluorescence (TADF), Organic macro-molecules, Blue emitters, Red emitters
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'RAPID MIGRAINE RELIEF WITH ALGINATE-BASED THIN FILM' (RAPID), addressing dissemination and exploitation.

assistant: **Impact**

Klaria's business concept is based on developing and commercializing innovative, fast-acting medicinal products with clear competitive benefits in the therapeutic fields of migraine and cancer-related pain. Migraine is the sixth most disabling illness in the world. The economic burden of migraine predominantly falls on patients and their employers in the form of bedridden days and lost productivity. The illness is three times as common in women than in men. However, existing drug delivery methods are not effective which results in low therapy satisfaction rates amongst migraine patients.Klaria developed an alginate-based polymer film capable of rapidly delivering the API (active pharmaceutical ingredient) directly into the bloodstream. The thin film is similar to a small postage stamp and is discreetly attached to the oral mucous membrane and allows the medication to be distributed into the bloodstream through the oral mucous membrane. The substance is delivered much more quickly (and thereby has a faster impact) than substances which are swallowed in tablets or capsules. Klaria’s film does not require taking an injection or suppository and ensures early intervention which is critical in order for migraine patients to experience pain relief. The film can be used by all migraine patients using medications based on triptans including those who experience concomitant vomiting during their migraine attack. Project RAPID, aims therefore to exploit the positive clinical performance of the buccal adhesive film, the company’s IP position and its ability to manufacture cost-effectively to launch an innovative migraine to contribute to an improved quality of life for migraine patients.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The Next Generation Grid' (NEXTGRID) targeting Sixth Framework.

assistant: **Abstract**

The goal of NextGRID is to develop architectural components that will lead to the emergence of the Next Generation Grid. This will prepare the way for the broader use of Grid technologies and their widespread adoption by organisations and individuals from the business and public domains. This widespread use will be a significant step towards meeting the vision of ERA and the goals of the e-Europe Action Plan. We will achieve these goals by extending the Grid architecture in three phases:1. Meeting the needs of business users: by addressing security and economically viable business models;2. Enabling participation by the public: by addressing legal and privacy issues, and making the Grid more scalable and usable;3. Consolidating and standardising these enhancements and stimulating take-up. NextGRID regards these objectives as a community effort and will focus on inspiring, through specific innovations and technical leadership, key progress in open Grid standards. We intend to provide the key initiatives for success, but expect to encompass the much wider body of work needed to define, agree and implement the next generation Grid. NextGRID will last for three years, and consist of integrating activities on architecture, standards and business/operational issues, plus development activities on Grid foundation services and protocols, dynamic federation, user interactions and representative applications, and a coherent dissemination and outreach activity. The scope of the work will address the possible convergence between Grid and Web services, and between Grid and P2P architectures, as well as new aspects such as the Semantic Grid. The overall result of the project will be a collection of new architectural designs, key middleware components, application support mechanisms,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'GalileO-based trustEd Applications for health and SustainabilitY', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

GNSS user technology is now widely available in mass market devices including personal devices, connected vehicles, Internet of Things (IoT) objects, etc. The widespread availability of GNSS receivers, joint with ubiquitous communication capabilities of devices and the ability of cloud-based ICT platforms to federate with each other through open standards and APIs, is enabling a new generation of Location Based Services (LBS) able to support highly-scalable pervasive applications where large number of geographically-distributed users are engaged e.g. in immersive games and commercial services. While GNSS proves to be able to support such applications successfully, a major drawback prevents such approach to be used in more serious (and potentially highly rewarding) mass market applications i.e. the lack of authentication features, resulting in high difficulties in preventing users from spoofing position information to gain advantages or damage other users.GOEASY will leverage unique Galileo features such as increased trust and improved availability, joint with interoperability with existing Internet of Things (IoT) infrastructures to enable more secure and privacy-savvy mass-market applications of LBS.GOESY will be evaluated by means of two concrete use cases, namely the ApesMobility and the AsthmaWatch, both evaluated engaging real users in a medium-scale pilot in Torino (Italy) and Stockholm (Sweden).


**Keywords:** Trust, e-security, smart city, mobility
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Hypervalent Chemistry and Catalysis', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The use of hypervalent compounds as homogeneous redox catalysts represents a departure from the stoichiometric use of main group reagents in synthesis. The methods proposed here are expected to hold significant promise for application in complex small molecule synthesis. The repertoire of oxidative ligand coupling reactions developed is expected to complement, and in some cases compete with, known transition metal catalyzed processes. A vital corollary to the synthetic studies outlined above involves the development of a more intimate understanding of the stereoelectronic features that govern ligand coupling reactivity. Although there currently exists no broad and effective treatment of main group ligand coupling that links data about one- and two-electron redox potentials to the observed bond forming reactivity, probing this connection may prove crucial to unlocking additional facets of this chemistry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Underwater Time Of Flight Image Acquisition system'.

assistant: **Concept**

UTOFIA will offer a compact and cost-effective underwater imaging system for turbid environments. Using range-gated imaging, the system will extend the imaging range by factor 2 to 3 over conventional imaging systems, while at the same time providing video-rate 3D information. This will fill the current gap between short-range, high-resolution conventional video and long-range low-resolution sonar systems.UTOFIA offers a new modus operandi for the main targeted domains of application: marine life monitoring, harbour and ocean litter detection, fisheries and aquaculture stock assessment, and seabed mapping.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'HIGH-RESOLUTION FUNCTIONAL OPTICAL IMAGING OF CHEMORESISTANCE' (CHEM-SCAN), addressing dissemination and exploitation.

assistant: **Impact**

The development of chemoresistance, i.e. the ability of cancer cells to evade treatment, has become a major challenge for current cancer therapy and significantly contributes to most tumor relapses and deaths. Changes in the way how sub-populations of cancer cells process metabolites have been identified as an indication of tumor chemoresistance: multiple different metabolites were found and identified in several chemoresistant tumors, which are attributed to facilitate tumor cell survival under chemotherapeutic stress. Identifying cells that can resist chemotherapy by adapting metabolite processing is, however, difficult, because this requires assessing the biochemical state of many cells at the single cell level and for multiple metabolites, simultaneously. A key limitation is that currently no single non-invasive platform exists that can be utilized in a highly parallelized fashion to monitor chemoresistance at the cellular and tissue level. CHEM-SCAN will develop novel fluorescent probes for the energetic/reductive state of cells, metabolites, and metabolic indicators that can assess chemoresistance of single cells. These probes will be assessed with highest sensitivity and spatiotemporal resolution by CHEM-SCAN's novel high-speed fluorescence lifetime imaging (FLIM) platform across multiple length scales. This FLIM platform will allow biomedical and clinical researchers to determine and follow the individual responses of human cancer cells to chemotherapy, enabling the assessment of individualized treatment options. Using the platform, alternative options for the individualized treatment of chemoresistant tumors, such as the combination of multiple drugs or the testing of new drugs can rapidly be conducted in-vitro without posing additional burdens on the patient.