RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Dry flux modification for coating quality improvement of silicon steels and reduction of zinc consumption in hot -dip galvanizing' (1998-2002) under Fifth Framework.

assistant: **Objectives**

In GeneraI Galvanising, the industrial problem to overcame is relevant to the so-called Silicon reactive .steels for which the hot-dip galvanized coating is too-thick, fragile and dark-grey Based on some promising preliminary results, the goal of this project is the set-up of a modified flux solution for general galvanising allowing :- to reduce the interface reactivity of Silicon reactive steels in a molten zinc bath (Sandelin type with Si=0.05-0.15 and iper-Sandelin Si>0.15%) in order to achieve for these steels the same quality of non-reactive steels;- to eliminate localised outburst in the coating due to local surface accumulation of Si .Besides the already experimented Ni salts, flux solution will be modified using salts funned with ions of metals such as Mn, Sn, Al, V, etc. and/or their combination as they have shown interface reaction reduction capability, for the so-called iper-Sandelin steels.Research work shall be divided in tasks:Starting reference flux solution based on Ni salts;Addition of elements salts, other than Ni, effective in reducing steels reactivity;Optimisation of the most promising solutions applied to several steel grades;Industrial implementation of lab results.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Metaplastic Spintronics Synapses'.

assistant: **Objectives**

In METASPIN we envision a radically new low-power artificial synapse technology based on spintronics nanodevices that will prevent catastrophic forgetting, i.e. the loss of memory of previously learned tasks upon learning new ones, a major flaw currently faced by all artificial intelligence applications.We will develop a new class of neuromorphic hardware that will use magneto-ionics to support synaptic metaplasticity, i.e. a feature inspired by the human brain based on assigning a hidden value to the states of artificial synapses to encode how important each state is. This will make it easier or harder to reconfigure the synaptic state upon learning a new task, giving a hierarchy to previously learned information and thus preventing catastrophic forgetting. The synaptic states will be given by the two magnetisation orientations in ferromagnets with perpendicular magnetic anisotropy, and by ferro/antiferromagnetic order in materials where the two phases coexist. In all cases, magneto-ionic gating will be used to locally modulate intrinsic magnetic properties to assign hidden states to each synaptic state. The magneto-ionic hidden states will translate into a modulation of the switching probability between synaptic states, introducing the metaplasticity functionality. In parallel, we will develop ANNs learning schemes, adapted to our device physics and inspired by biological synaptic activity, that can learn with mitigated catastrophic forgetting. The ultimate goal of this project is to integrate this advanced synaptic technology and learning algorithms into an ANN demonstrator to test multitask learning on proof-of-concept tasks inspired by medical AI, and assess the impact of metaplasticity in catastrophic forgetting.


**Keywords:** Artificial synapse, magneto-ionics,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Uncertainty Quantification for Composite Structures Under Impact Loading' in the context of a Horizon 2020 call.

assistant: **Objectives**

Carbon fibre reinforced composites (CFRP) have been increasingly used in aeronautical/aerospace structures given their outstanding specific stiffness and strength. However, CFRPs exhibit weak through-thickness strength, making them susceptible to impact damage, a design driver for aerostructures. Induced impact damage may reduce the compressive strength of the structure, and the inherent complex damage mechanisms of CFRP are difficult to predict. With a better predictive capability, structural design could be faster, cost effective and lead to a lighter and more damage tolerant nal structure. In reality, experimental characterisation of these CFRPs reveals appreciable variability of material properties, attributed to a complex heterogeneous microstructure, among others. This action (CERTAINTY) aims at developing the next generation methodology for predicting the mechanical response of CFRPs under impact loading by accounting for uncertainty in material properties and harnessing this in a physically-based damage model across different scales. CERTAINTY will provide a robust computational framework by introducing probabilistic models in contrast to traditional deterministic ones, by employing: Monte Carlo and metamodel techniques when the Monte Carlo approach is not suitable. CERTAINTY will further enable the researcher to establish collaborations with leading industrial partners. Targeted training will enable the researcher to develop a research career as a world expert in the design of CFRP aerostructures quantifying uncertainties associated with damage modelling. By demonstrating how damage mechanisms vary in a CFRP under impact loading, taking fracture toughness and material parameters variability into account in the damage modelling, the researcher and the host will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Dimerisation behaviour and ligand binding of glycopeptide antibiotics in the presence of d-alanyl-d-lactate cell wall analogues' to be submitted under Fourth Framework.

assistant: **Abstract**

Research objectives and content The phenomenon of antibiotic resistance in pathogenic bacteria is a serious threat to human health. The antibiotic of last resort is the glycopeptid vancomycin. However, a current rise of vancomycin resistant enterococci (VRE) is observed. This is alarming since there is no drug that can effectively treat a VRE infection. Dimerisation of this antibiotic plays an important role in its antibiotic action, which is promoted by binding to cell wall analogues as di-N-Ac-Lys-D-Ala-D-Ala. Furthermore the introduction of a membrane anchor increases the antibiotic activity. Binding between model systems carrying an D-alanyl-D-lactate residue shall be investigated by NMR techniques and UV difference spectroscopy. A comparison with other cell wall analogues with known binding constants will help to optimise lead structures. As a whole the results will provide substantial information about the mode of antibiotic activity. Training content The project will allow to improve the fellow's knowledge about peptide chemistry and NMR-spectroscopic analysis of these compounds. We hope to be able to find ways to overcome the phenomenon of antibiotic resistance by development of new lead structures in antibiotic research. Links with industry Any lead structure would be further developed and merchandised by the European pharmaceutical industry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Precise Genome Editing to Correct Cardiomyopathies in Human Cardiac Organoids', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Inherited cardiomyopathies are a major cause of sudden cardiac death and are caused by mutations in genes encoding sarcomeric proteins. With an incidence of 3 per 1,000 adults within the European population, inherited cardiomyopathies present a substantial burden to the healthcare services of all European nations. Although a few medications can slow the progression of the disease, today there is no cure for cardiomyopathies. The CRISPR-Cas9 precision genome editing technologies, base and prime editing, can permanently edit point mutations of genes, making them ideal tools to treat cardiomyopathies. To demonstrate the efficacies and therapeutic benefits of these editors in correcting cardiomyopathy-causing mutations, it is necessary to develop robust in vitro models of mature human cardiomyocytes that recapitulate the cellular complexity of the human heart. In the Edit-hCOs project, I will generate and characterize human cardiac organoids (hCOs) harboring clinically relevant cardiomyopathy-causing mutations in the FLNC gene, which encodes for the sarcomeric protein filamin C. hCOs will be generated as three-dimensional scaffold-free cardiac microtissues using tri-cellular combinations of human induced pluripotent stem cell -derived cardiomyocytes, cardiac fibroblasts, and cardiac endothelial cells. Then, I will deploy base and prime editors to fix common FLNC gene mutations in the hCOs, and I will characterize their molecular and functional improvements following correction. In addition, I will generate humanized mouse models harboring the same mutations as patients for future studies on delivery, therapeutic safety, and efficacy of the genome editing components in vivo. Completion of the Edit-hCOs project will allow me to establish a completely innovative and ambitious
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Paying attention to food: investigating the mechanisms underlying individual differences in the attention grabbing properties of food' under Seventh Framework.

assistant: **Concept**

We are surrounded by images of food in our daily lives and for some people this is a problem because they find it difficult to ignore food and are provoked into craving food and eating when they see food or pictures of food. This can lead to unhealthy weight gain. Therefore we need to understand more about why certain individuals seem to pay lots of attention to food in the environment and what might explain differences across individuals. This project will combine cutting edge cognitive psychology methods with genotyping to investigate the mechanism underlying individual differences in food attention and whether the amount of attention that is paid to food is influenced by the presence of a common genetic type associated with overweight and obesity. We have data to show that more attention is paid to food when participants in an experiment are also holding information about food in memory. Our results suggest that this interaction between memory and attention is very strong for food and could explain why people who are thinking about food a lot, for example, people who are overweight, find it  particularly difficult to ignore food when they see it. Objective 1 will build on these results by using a measure of brain function to find out whether these memory effects occur very early in the processing of food images and are likely to be involuntary. The second objective is to find out whether individuals who have different genotypes that are relevant to weight control pay more attention to food cues and are more susceptible to the effects of memory on attention. Objective 3 will be to assess the role of specific brain areas in the effects of memory modulation of attention and relate these effects to genotype differences. The project will provide information that will enha
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Multilingual democracy experiments in movements: from transnational activists to local decision-makers'.

assistant: **Objectives**

The project brings together a micro-sociology of democracy with a politics of multilingual deliberation in arenas of protest and decision-making. Designed as a pilot study, the project will explore the relevance that activists’ practices of face-to-face translation, developed for transnational discursive democracy experiments in social movements, can have for activists and officials also at domestic level in multilingual group settings. Having conducted two comparative studies on supranational discursive arenas in the European Social Forum (ESF) and the World Social Forum, I could show that surprisingly, activists’ practice of voluntary translation at the European level helps better including traditionally disadvantaged groups in deliberation compared to monolingual national social forum network assemblies studied. I would like the Marie Curie mobility to propose a case study that will increase the systematic relevance of my result, by studying multilingual democracy experiments also at the national and local levels, as envisaged by the EC’s research perspective (EC 2008). I propose a multi-disciplinary case study on the diffusion of European ideas and experiences of multilingual democracy to activist groups and local authorities in the United States who introduced translation, learning from Europeans as organizers of self-organized translation in the ESF. This is an original case for exploring the diffusion of European experiences and ideas on linguistic diversity and inclusivity, not by EU policy makers or institutions, but by European activists who spread their distinct practices of translation across transnational discursive arenas. I will clarify whether alternative multilingual organized democracy experiments, and translation, may enhance inclusive dialogue compar
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Optical Data Payload for Small Satellites – A complete satellite platform with integrated optical communications system for increased data transfer rates.'.

assistant: **Objectives**

Current radiofrequency communication systems for satellites are very bulky and require high amounts of power. This can be compromising for small satellite platforms.ODALISS is a complete satellite platform, with integrated optical communications system and all the platform sub-systems (Satellite bus, OBC, ADCS, Power), ready to accommodate third-party payloads such as observation or scientific equipment. This means that customers can buy the full satellite from emxys, install their own instruments, and then it is ready for launch. The high down-link data rates will be ideal for low cost satellite developers who handle large amounts of data (such as those related with Earth Observation, environmental monitoring, etc.). These will be able to download their data either via Web, through the emxys central Optical Ground Station (OGS), or through their own OGS. Optical free-space links are prone to failure due to interruption caused by atmospheric obstacles (fog, clouds, rain, etc.). In order to overcome this drawback, we are establishing a series of OGS around the globe in strategic locations where the atmosphere is clear and more predictable. Such locations are in many cases compatible with those chosen for astronomical observations.emxys is an innovative aerospace SME with over 12 years of experience in the sector, we are aspiring to evolve our business model with a recurrent activity based on a proprietary product line, while maintaining the existing activity in on-demand developments and participation in project consortia. During the last 6 years emxys has focused on the development of proprietary satellite platform product line, starting with the 3U CubeSat platform NAOSAT. ODALISS is the next evolution of the NAOSAT platform by integrating a built-in optical communicat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Advanced study course in river basin modelling for flood risk mitigation' (ADC-RBM), addressing dissemination and exploitation.

assistant: **Impact**

The proposal is concerned with organising an advanced study course in river basin modelling and flood risk management with a view to disseminate recent findings to young researchers and professionals. The dissemination of knowledge will be achieved through a series of lectures/ workshops presented by eminent specialists and two field trips. The course is relevant since flooding claims about a third of all the damaged cause by natural disasters and timely: the recent flooding in Europe and other continents caused substantial damage, disruption, and distress. These are only two recent inundation catastrophes that are fresh in the minds of people. Such disasters stimulate the search to improve methods of mitigating flood risk so as to reduce the impact of flood hazards. Hence it is imperative that the latest information is presented to those who can act to immediately improve the situation, i.e. researchers and professionals.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Synthetic nicotinamide cofactors for new and improved biocatalytic processes'.

assistant: **Objectives**

Over the past years, intensive research has been done in pursuit of the development of nicotinamide cofactor recycling systems in oxidoreductase-catalysed reactions, to reduce the overall cost of biocatalytic systems. However, there is still a need to overcome the challenging drawbacks, such as undesired side-reactions, of using these cofactor-dependent enzymes.The aim of this project is  to design and develop synthetic nicotinamide cofactors (mNADs) to be accepted by oxidoreductase enzymes and thus improve biocatalytic processes. The main objectives are (i) an in-depth understanding of the catalytic mechanism of mNAD-driven regeneration with enoate reductases, (ii) expanding the scope of mNADs to other enzymes through protein engineering, and (iii) a preparative exploitation of the optimised system.Thus, the initial part of this project will be the synthesis of novel mNADs, obtaining a library to be used with enoate reductases to analyse the enzyme mechanism with these biomimics. Further on, variants of an alcohol dehydrogenase will be engineered to expand the scope of the mNADs to other enzymes. Finally, the system will be optimised for preparative scale through a newly designed mNAD recycling system. An enzyme screening kit is also envisaged to be developed.The objective of this innovative and timely proposal is to provide training in the multidisciplinary fields of organic chemistry, biocatalysis, molecular biology and protein engineering. This proposal is expected to help the applicant reach a position of professional maturity and start an independent career in academia. Benefits for the European Research Area include a new line of research, and the obtained results will be patented and published in high quality journals, with applications to the industrial sector.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Solvometallurgy for critical metals' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The recent “rare-earth crisis” has brought about the widespread realisation that the long-term availability and cost stability of many materials – not just the rare earths – can no longer be guaranteed. Increasing the levels of critical metal recycling from pre-consumer, manufacturing waste and complex, multicomponent end-of-life consumer products is considered as arguably the most important and realistic mitigation strategy. However, extracting a critical metal from complex waste is a very different challenge to that faced when attempting to produce a pure metal from a primary ore deposit. SOLCRIMET therefore develops a ground-breaking, novel approach called “solvometallurgy”, a new branch within metallurgy, next to conventional hydro- and pyrometallurgy. SOLCRIMET’s aim is to successfully apply this approach to the extraction of specific critical metals, i.e. rare earths, tantalum, niobium, cobalt, indium, gallium, germanium and antimony. As these critical metals are essential components for clean-tech and high-tech applications, they are key enablers of the required transition to a low-carbon, circular economy. The approach involves the discovery of non-aqueous solvent pairs that are immiscible and allow the extraction of metal complexes at moderate temperatures, leading to high-purity recycled metals. The idea is certainly high risk, but the preliminary results already obtained are highly encouraging. The main outcomes of the project will be lab-scale demonstrators that show the enhanced efficiency, utility and applicability of the new solvometallurgical process, with respect to conventional hydro- and pyrometallurgy. SOLCRIMET’s impact on chemistry, chemical technology, metallurgy and materials engineering science will be game-changing. The possibility to recycle c