RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Communication Agents for Mobility Enhancements in a Logical Environment of Open Networks' (CAMELEON) targeting Fourth Framework.

assistant: **Abstract**

Main Objective Existing telecommunication service and management architectures, such as IN (Intelligent Network) and TMN (Telecommunication Management Network), are based on the traditional RPC (Remote Procedure Call) paradigm of computing and provide services in a centralised manner. Service and management intelligence are located in only a few centralised network nodes, which results in potential communication inefficiencies and bottlenecks, and makes it difficult to achieve effective on-demand and customised service provision. New, innovative services are notoriously slow and difficult to implement. Due to their inherent autonomy and mobility, mobile agents offer new possibilities for the provisioning of as yet unknown services in the emerging electronic service markets. By allowing the movement of both code and data, mobile agent systems have an extremely high potential to optimise the use of low-bandwidth, high-latency or unreliable network connections typical for mobile service environments. In addition, Agent Technology allows for rapid service deployment. These expected advantages have yet to be proved in scientific evaluations. Key aspects of advanced communication services and applications in the near future will be personalisation and scalability. As a multiplicity of networks and transmission protocols will remain, users will look for seamless access to their personalised set of services from any suitable access point in either fixed or mobile networks, using different user devices. The main objectives of CAMELEON are therefore to develop and trial:  -service roaming features through the application of agent technology in an Integrated Broadband Communication (IBC) architecture, exemplified with the Virtual Home Environment (VHE) developed for the Universal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Impact of qualitative chemical analysis in the vi framework programme : networking with newly associated states' (IQUALAN-NAS).

assistant: **Innovation**

The main aim of this proposal is to plan and develop a workshop on the impact of qualitative analysis in EU policies and the 6th Framework Programme based on the conclusions and recommendations of the accompanying measure Metrology of Qualitative Chemical Analysis which will be finished in April 2002. A modern basic approach to metrology of binary responses, the Quality Assurance principles and practices in this type of analysis as well as the identification of analytical tools and specific application areas are the basic topics to be disseminated in the meeting. A substantial part of the workshop will be devoted to discuss and plan the future cooperation of Newly Associated States through networking in the VI Framework Programme and in this way promotion the transfer of knowledge in measuring and testing.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'From industrial CO2 streams to added value Fischer-Tropsch chemicals' (ICO2CHEM) under Horizon 2020.

assistant: **Objectives**

The overall aim of the project is to develop a new production concept for converting CO2 to white oils and aliphatic high molecular weight waxes. The products are used for wax emulsions and white oils to be used in coatings and sealant materials The properties of the raw materials will be tested against current fossil based materials. The main raw material for the process is CO2 which is available from processes currently operating at a large industrial site with significant annual CO2 emissions. H2 is obtained as by product from a chlor-alkali plant on the site. Currently H2 is produced in excess and it is used mainly for energy production. Currently at this chemical production site about 2 million tons/a of CO2 is vented to the atmosphere, creating a huge GHG emission reduction potential. The core of this project is a combination of reverse water gas shift (RWGS) coupled with advanced, modular Fischer-Tropsch (FT) technology. The RWGS-step converts CO2 with H2 to carbon monoxide. The following FT-reaction step will be carried out in a novel intensified reactor recently developed and patented by Ineratec. Over 1500 kg of white oils and high-molecular weight wax will be manufactured using a container-sized microstructured reactor system. Techno-economic and environmental assessments will be carried out to demonstrate the potential of the new concept in different locations and integration sites. A business plan will be formulated in the project for a follow-up of a commercial industrial demonstration project.


**Keywords:** Chemicals from CO2, Fischer-Tropsch, white oils, high molecular weight waxes, coatings sealants, greenhouse gas reduction, carbon capture and utilisation, heat exchanger reactor, RWGS, CVD
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Charting a New Horizon of Big and Fast Data Analysis through Integrated Algorithm Design' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

This proposal addresses a pressing need from emerging big data applications such as genomics and data center monitoring: besides the scale of processing, big data systems must also enable perpetual, low-latency processing for a broad set of analytical tasks, referred to as big and fast data analysis. Today’s technology falls severely short for such needs due to the lack of support of complex analytics with scale, low latency, and strong guarantees of user performance requirements. To bridge the gap, this proposal tackles a grand challenge: “How do we design an algorithmic foundation that enables the development of all necessary pillars of big and fast data analysis?” This proposal considers three pillars:  1) Parallelism: There is a fundamental tension between data parallelism (for scale) and pipeline parallelism (for low latency). We propose new approaches based on intelligent use of memory and workload properties to integrate both forms of parallelism.2) Analytics: The literature lacks a large body of algorithms for critical order-related analytics to be run under data and pipeline parallelism. We propose new algorithmic frameworks to enable such analytics.3) Optimization: To run analytics, today's big data systems are best effort only. We transform such systems into a principled optimization framework that suits the new characteristics of big data infrastructure and adapts to meet user performance requirements.The scale and complexity of the proposed algorithm design makes this project high-risk, at the same time, high-gain: it will lay a solid foundation for big and fast data analysis, enabling a new integrated parallel processing paradigm, algorithms for critical order-related analytics, and a principled optimizer with strong performance guarantees. It will also br
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Gut microbiota, innate immunity and endocannabinoid system interactions link metabolic inflammation with the hallmarks of obesity and type 2 diabetes' (ENIGMO), addressing dissemination and exploitation.

assistant: **Impact**

Obesity and type 2 diabetes are characterized by metabolic inflammation and an altered endocannabinoid system (eCB) tone. We have provided evidence that gut microbiota modulate both intestinal and adipose tissue eCB system tone. Insulin resistance and inflammation have been linked to microbiota-host interaction via different Toll-Like Receptors (TLR’s). Our preliminary data show that tamoxifen-induced epithelial intestinal cells deletion of the key signalling adaptor MyD88 (myeloid differentiation primary-response gene 88), that encompass most of the TLR’s, protect mice against diet-induced obesity and inflammation. A phenomenon closely linked with changes in the intestinal eCB system tone and antimicrobial peptides production. Moreover, we discovered that the recently identified bacteria living in the mucus layer, namely Akkermansia muciniphila, plays a central role in the regulation of host energy metabolism by putative mechanisms linking both the intestinal eCB system and the innate immune system. Thus these preliminary data support the existence of unidentified mechanisms linking the innate immune system, the gut microbiota and host metabolism. In this high-risk/high-gain research program, we propose to elucidate what could be one of the most fundamental processes shared by different key hallmarks of obesity and related diseases. A careful and thorough analysis of the molecular and cellular events linking gut microbiota, the innate immune system and eCB system in specific organs has the potential to unravel new therapeutic targets. We anticipate the key role of MyD88 and the enzyme NAPE-PLD (N-acylphosphatidylethanolamine phospholipase-D) involved in the synthesis of N-acylethanolamines family to be key determinant in such pathophysiological aspects. Thus, these app
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Software for computer aided neutro, scattering' (SCANS), addressing dissemination and exploitation.

assistant: **Impact**

Objectives:The objective of the SCANS project is software development that enables significantly more cost effective and scientifically productive use of existing neutron scattering facilities, and provide opportunities for the design of future instrumentation and the utilisation of existing and future neutron sources. SCANS aims to encourage collaboration in software development not only between the partner laboratories, but also all other neutron scattering facilities and their users.Results:During the first year we have carried out development of the McStas, VITESS and RESTRAX simulation packages, the NeXus data format and RMC data analysis routine s. Detailed instrument simulations are being carried out, in particular in relation to the ESS project. Most generic instrument types can be simulated though further work is required on the details of components, including samples, particularly for the description of polarised neutrons. Preliminary work has begun on the coupling of instruments/simulations to high level data analysis in order to produce 'virtual instruments' or automated experiment control, which depends on the scientific results obtained.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Fundamental groups, etale and motivic, local systems, Hodge theory  and rational points' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

From the viewpoint of geometric classification, there are two extreme cases of smooth varieties X defined over an algebraically closed field: those which are hyperbolic, and those which are rationally connected.  If k is no longer algebraically closed, a central question of Algebraic Arithmetic Geometry is what properties of k force  X to have a rational point in those two opposed cases.   It is conjectured (Lang-Manin, extended by Kollár), that rationally connected varieties have a rational point over a C1 field. It has been shown for function fields by Graber-Harris-Starr  and by myself over a finite field. There is no relation between their geometric proof relying on the geometry of the moduli of punctured curves and my proof relying on motivic analogies between Hodge level and slopes in l-adic cohomology. The study of the case of the maximal unramified extension of the p-adic numbers might provide a bridge through the use of the inertia.  Very little is known on Grothendieck's section conjecture, which predicts that sections of the Galois group of k, assumed to be a finite type over Q,  into the arithmetic fundamental group of X, are given by rational points. Our hope goes in two directions, arithmetic and geometric on one side, motivic on the other.  With Wittenberg, we hope to use Beilinson's geometric description of the nilpotent completion of the fundamental group, and with Levine, we wish to characterize sections of the motivic groups of mixed Tate motives over k and X and relate this to the section conjecture.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Understanding Crystal Polymorph Control in Confinement using In-situ TEM' (PolyTEM) targeting Horizon 2020.

assistant: **Abstract**

Controlling the polymorph (crystal structure) of crystalline materials is of vital importance to both material science and the pharmaceutical industry. Many crystal polymorphs are difficult to access, however, as polymorph is determined by both kinetics and thermodynamics. Recently, it has been observed that precipitation of crystals in confinement often leads to the formation of unusual polymorphs. For example, CaCO3 forms purely as aragonite when it is precipitated in small nano-pores. These observations suggest that confinement could offer a generic route to polymorph control. However, the fundamental mechanisms underlying this confinement effect are poorly understood. In this project, I will combine in-situ cryogenic transmission electron microscopy (cryoTEM) and liquid phase (LP) TEM to study how confinement effects give rise to polymorph control. In-situ cryoTEM allows detailed structural analysis of “snapshots” of the nucleation process, while LPTEM enables dynamic, time-resolved analysis with millisecond time resolution. Notably, although these two advanced techniques perfectly complement each other, they have never been combined to study one system.CaCO3 will form the principal focus of the study, and a graphene pocket (GP) will be used as the confinement system as it not only favours aragonite formation, but is also ideally suited to both cryoTEM and LPTEM studies. The study will reveal how CaCO3 nucleate in the GPs and develop into aragonite, and the role of surface chemistry in this polymorph control process will be investigated. The project will then be extended to functional materials (e.g., TiO2) or drug crystals (e.g., Ritonavir), in order to learn how to use confinement to control polymorph by design. The research will allow us to fully understand the f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Reinforcing of Nanotechnology and Functional Materials Centre' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

In recent years, the advance of contemporary technologies became more closely related to the development of new materials. Exploiting the possibility of designing new materials on micro and nano level as well as composite materials enables their use in various fields such as biomedicine, catalysis, civil engineering, aerospace and process industry. The aim of this project is to contribute to the advance in proposed fields by networking and reinforcing research centers in Serbia as an EU&apos;s Convergence Region, by organizing personnel exchange, performing joint experiments, teaching and training activities with EU networking research and industrial partners. In that way, the research project team will get strong expertise in the synthesis, processing, characterization and testing of nanostructured materials, establishing new advanced processing and characterization methods, also. Special care will be taken towards hiring of experienced and new young researchers in order to reinforce the human potential. This project will also result in upgrading and acquired of the S&T equipment of the centre in order to reinforce internal S&T capacities. This kind of collaboration will result in preparing further cooperative activities and preparation of new joint RTD proposals and reinforcing integration to European Research Area.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Mucosal Breaks of Bacteria Trigger Pathogenic B-cell Responses in ANCA-associated Vasculitis' to be submitted under Horizon Europe.

assistant: **Abstract**

ANCA-associated vasculitis (AAV) is a rare and severe autoimmune disease, characterized by inflammation of the small blood vessels. ANCAs, autoantibodies against proteinase-3 (PR3) or myeloperoxidase (MPO), play a central role in the pathogenesis. They induce excessive activation of neutrophils, resulting in necrotizing injury of small vessels. The loss of tolerance in AAV is thought to be the result of genetic, environmental, and ageing factors. Although infectious triggers are implicated, their exact role in the pathogenesis of AAV remains unclear. Previous studies demonstrated that AAV patients with chronic nasal carriage of Staphylococcus aureus or Corynebacterium tuberculostearicum exhibited a higher relapse rate, and eradication treatment reduced relapses. We hypothesize that pathogenic sinonasal mucosal breaks of bacteria activate autoreactive B-cells through molecular mimicry, resulting in autoimmune responses that mediate AAV. This proposal is to investigate the role of sinonasal mucosal breaks in AAV through repertoire sequencing of peripheral blood and tissue B-cells of AAV patients combined with 16S sequencing of the sinonasal bacterial microbiome. Subsequently, representative monoclonal antibodies will be expressed and reactivity towards ANCAs and sinonasal bacterial antigens investigated. Lastly, the findings will be validated by studying serum antibody reactivity in large cohorts of AAV patients. Success of the proposed studies would transform our understanding of the autoimmune responses in AAV, and potentially elucidate a mechanistic role for sinonasal mucosal breaks of bacteria in triggering disease initiation and progression. Further, success could lead to novel therapeutic approaches focused on preventing mucosal breaks and/or clearance of pathogenic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Complexity in cosmology', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

The physics of scale invariant and complex systems is a novel field which is including topics from several disciplines. This widespread interdisciplinary corresponds to the fact that these ideas allow us to look at natural phenomena in a new and original way, leading to unifying concepts . This project aims to study the complex, scale-invariant structures which appear in the gravitational clustering both from a theoretical and experimental points of view.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Prognosis and Diagnosis of Protein Misfolding Diseases by Seeded Aggregation in Microspheres' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

There is currently no early detection system for neurological protein misfolding disorders (such as Alzheimer's and Parkinson's diseases) that would satisfy the demands for rapid, quantitative, flexible, and reproducible assays to study amyloidogenesis in biological samples. We will explore the potential of aggregation assays in microdroplets that are formed in microfluidic devices. We have found that the readout of this assay reflects the disease progression, when samples of Drosophila fruit fly brains and mouse brain and serum are analysed. We will use this PoC project explore the utility of this technology to report on aggregation of amyloid precursors in human biological samples, to test whether the potential of this technology extends to patients diagnosis and prognosis. Such data would resolve the question whether our early diagnosis system is immediately useful in a medical context and strengthen the case for venture capital funding.