RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'ENHANCING BIO-BASED INNOVATION AND PARTICIPATION IN UNDER-REPRESENTED  REGIONS THROUGH CLUSTER MOBILIZATION AND COLLABORATIVE GOVERNANCE' (BIO-INSPIRE), addressing dissemination and exploitation.

assistant: **Impact**

Regional clusters are the unsung heroes of sustainable development, driving innovation and economic growth by leveraging local ecosystems and fostering strong connections among businesses, research institutions, and stakeholders. This is even more valid for Clusters in Bioeconomy, where new knowledge is born constantly The project´s collective understanding is that Regional Bio-Economy Clusters are ideally suited to mobilise R&I ecosystems, due to their cross-sectoral nature of bioeconomy in different countries, their proximity to local enterprises, and their ability to reflect common bottlenecks and needs and link the local ecosystem with international knowledge and funding hubs. BIO-INSPIRE, an alliance of 14 transdisciplinary entities from 12 EU countries, demonstrates that  regional bio-economy clusters are a valid answer to developing bio-based innovations, driving sustainable growth and fostering resilient local economies across the widening regions of Eastern and Southeastern Europe. BIO-INSPIRE will engage Regional Bio-Economy Clusters in 7 widening countries (Greece, Hungary, Slovakia, Lithuania, Romania, Bulgaria and Poland, ) and research and technology developers and clusters in 2 non-widening countries (Sweden, The Netherlands) to address systemic causes of underdevelopment across geographical boundaries. BIO-INSPIRE aims to contribute to the transformation of the widening regional bioeconomies by addressing existing bottlenecks and providing to the regions the necessary tools to advance their R&I capacity and their ability to broader their collaboration networks. At the heart of this project is the provision of a Governance Model framework, addressing the critical lack of established structures, norms, and procedures for sustainable collaboration. This fra
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Translational specialization of cellular identity in embryonic development and disease' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

A central question in developmental biology is how the genetic information is differentially interpreted to program cell-fate decisions essential for embryogenesis. The success of developmental cell-fate decisions relies on the accurate rewiring of the proteome to support rapid cellular identity changes. Here, we will address the fundamental question: How is the developmental transcriptome differentially translated in time and space to program cell-fate decisions? I hypothesize that the developmental competence for cell-fate decisions is controlled by fate-specific translational specialization factors (TSFs). TSFs program the selective and privileged translation of developmental genes in defined time windows to enable the acquisition of cell fate and maintenance of cellular identity. Notably, in a proof-of-principle study, we discovered that translational specialization in pluripotency poises future lineage choices in humans. The research program TRANSCEND has four work packages: (1) identifying candidate TSFs engineering cardiac fate at critical cell-fate transitions by cell-fate specific, systematic cataloging TSFs on ribosomal complexes; (2) dissecting the molecular and functional role of TSFs in cardiac cell-fate specification by combining targeted CRISPR screens and tethered functional approaches; (3) decoding the mechanisms, modalities, and design principles by which TSFs program cardiac identity by using a holistic approach, including loss-of-function studies in cardiac 2D, organoid, and mouse models along with systems-wide methods such as eCLIP-seq and TCP-seq; and (4) engineering translation specialization modules to ameliorate pathological cardiac hypertrophy using patient-derived in vitro and murine in vivo models. Ultimately, the proposed research program TR
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Lithium Carbon Liquid Electrolyte Batteries Performances Improvements and Cost Reduction' (1994-1998).

assistant: **Concept**

Objectives and content The development of Electric Vehicle is presently limited by the availability of energy storage batteries with high level performances adapted for the application (Specific Energy, Power density, Cycling capability) and Low Cost. Among the different battery technologies that are being considered, the Lithium Carbon using liquid electrolyte appears to be the most promising system for different applications and specially to meet the E.V. application requirements. This conclusion has been recently confirmed by European car manufacturers coming after a comparative analysis of the different potential technologies. The objectives of this RTD project is to optimize the most critical materials and associated technologies in order to: - Improve and control the system performances specially:  - the capacity and its decrease in cycling,  - the characteristics at temperatures different from room temperature: irreversible self discharge at high temperature (>45°C) and discharge rate at low temperature (-30°C). - Prepare the cost reduction. The major part of the electrochemical components cost is ascribed to specific materials and their processing: positive material, electrolyte, separator. The material specifications and the factors that affect the cost must be studied and controlled in order to reach the objectives required for an industrial step. The programme must prepare, for Electric vehicle and other applications, the development phase of the Lithium Carbon technology anticipated for 1998 . The technical results obtained will be transferred by the end of the project to the Development Units of each industrial company involved in the project. The consortium includes: - Industrial companies involved in materials fabrication (SEDEMA, SOLVAY, MERCK), - An ind
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'HOMES Key INsulating material'.

assistant: **Concept**

The Advanced Aerogel-Based Composite (AABC) materials are a unique new class of materials. The HOMESKIN project aims at developing a new silica Advanced Aerogel-Based Composite material possessing the lowest thermal conductivity of all insulation materials found in the market. The proposed solution will bring to the market new insulation technologies that do not only possess very high thermal insulation performance but also are thinner, lighter, non flammable, and with lower CO2 and VOC emissions. The new material developed can be applied to new buildings as well as for old buildings retrofit applications. Among our objectives in this project are to develop more sustainable construction with lower embodied energy, and develop healthy, fire resistant and moisture controlled insulating layers, as well as eco-innovative binders and adhesives, to enhance the durability and reduce maintenance costs, and to demonstrate the energy and health efficiency of building envelopes based on such new materials. The HOMESKIN project shall bring key contributions to the very high performance insulation standards and policies. Different tasks will be carried out by the partners involved. One part of the work is dedicated to the material development. This material will become the basis for the development of the insulation systems. Coatings and interface materials will be developed according to the AABC integration in the insulation systems solutions (for inside, outside, singular points and thermal bridges insulation applications). These advanced insulating systems will be assessed to validate their acoustical, thermal, hygrothermal, fire safety, and VOC emissions properties. A life cycle analysis will also be performed. The performances of these solutions will then be tested on buildings
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Pulsed Laser Light and Nano-encapsulated Ocular Dyes for Advanced Therapies in the Eye', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Ocular diseases affect the quality of life of millions of patients. Despite improvements in pharmacological treatments, the arsenal of medications to treat severe ocular diseases today remains rather restricted to traditional drugs. Use of most modern biotherapeutics like proteins and nucleic acids, could be a major step forward. However, current ways of administration such as eye drops and intravitreal injections, are no longer sufficient to deliver these drugs to most targets in the eye. Therefore, novel concepts allowing biotherapeutics to safely overcome ocular barriers are of high interest. In ocular surgery, pulsed-lasers (P-Ls) are used for ‘tissue cutting’, though safety concerns remain. DYE-LIGHT hypothesizes that strategies which would allow the use of P-Ls in the eye at much lower energy than today, could considerably improve safety and pave the way for both novel ocular therapies and advanced surgical interventions. DYE-LIGHT will explore vital dyes, as used by ocular surgeons to stain tissues, as photosensitizers. DYE-LIGHT follows the recent observation that P-L irradiation of ocular dyes can result in the formation of water vapor nanobubbles (‘dye-based nanobubbles’) and thermophoretic transport (‘dye-based thermophoresis’). Interestingly, these biophysical phenomena occur at a laser energy that is ~ 1000 times less than a P-L alone. As compared to free dyes, dyes encapsulated in nanocarriers are expected to penetrate less into the retina, which might improve safety. Therefore, focus in DYE-LIGHT will be on nano-encapsulated ocular dyes. DYE-LIGHT will explore the potential of dye-based nanobubbles for delivery of nucleic acids in the corneal endothelium and for spatial selective vitreolysis in the eye. Finally, DYE-LIGHT will explore dye-based thermophor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Chiral Communications at the Nanoscale'.

assistant: **Concept**

Since the separation of enantiomers by Louis Pasteur we have realized that chirality has many important repercussions in our lives. In the last decades, the chiral properties of organic molecules in solution and adsorbed on surfaces have intensively been explored and analysed. At the same time, new chiral systems have been discovered, such as thiolate protected metal clusters and carbon nanotubes, both of which present intrinsic chirality at the nanoscale. However, the notion and the impact of chirality in these systems are still evolving and the research is mostly concentrating on the structure and optical properties of these materials. In contrast, the aim of the proposed project is to study the creation, amplification and transfer of chirality in thiolate protected gold clusters and carbon nanotubes.The proposed work will clarify fundamental aspects of chiral intermolecular interactions, enantioseparation processes and transfer of chirality at the nanoscale. As such it will have impact on many fields where both systems are crucial, such as in nanotechnology, nanomedicine and molecular electronics. Using clusters and carbon nanotubes with well-defined composition and structure will allow us to gain insight that is difficult to obtain otherwise. Particularly a large part of the project focuses on dynamic aspects of the metal-sulphur interface which plays an important role in many applications but which has been almost completely neglected up to now. Importantly, the project makes use of chiral vibrational spectroscopies extending the application of these techniques to the field of nanotechnology. Finally, transfer of chirality at the nanoscale is a promising topic to focus on for a young scientist because it is timely, touches fundamental aspects of science like symmet
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Interactive Tools for the Study and the Enhancement of Music Iconography' (In-Music) under Horizon Europe.

assistant: **Objectives**

While music is undoubtedly a primary expression of any civilization, Western society seems to have moved further and further away from the music of its past, thus missing a great wealth of its own identity. Rethinking how we approach historical music is essential to bridge this gap and IN-MUSIC intends to make an innovative contribution in this direction. The project will focus on a particularly interesting yet little-addressed branch of cultural heritage, music iconography, addressing it through a multidisciplinary approach that combines iconological methodology with the application of digital technologies.Due to the very nature of music iconography, digital technologies represent a tool with enormous potential for both its study and enhancement. In fact, only in a virtual context is it possible to reconstruct the original ideal multi-sensory nature of musical images while digital means allow the socialization of highly specialized music-related contents in a dynamic and engaging way. Nonetheless, little has been done to fully explore this potential, especially in terms of interactivity. IN-MUSIC will address Early Modern Spain music iconography and will delve into different digital approaches and communication strategies, in order to devise replicable and versatile instruments. A semantic database, based on CIDOC-CRM, and a set of prototypes of digital devices will be elaborated, resorting to the use of different open-source software. All the prototypes will be submitted to different targets of public who will be asked to fill out a specifically designed survey to collect useful data for the evaluation of the effectiveness of such tools in communicating knowledge.The success of the action will therefore increase our knowledge on Spanish musical imaginary in a crucial
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Data-driven cancer genome interpretation for personalised cancer treatment' (CGI-Clinics), addressing dissemination and exploitation.

assistant: **Impact**

CGI-Clinics aims at improving personalised medicine in oncology by optimizing genomic data interpretation (after sequencing and before advising on compatible targeted therapies). Interpretation is a bottleneck for the full deployment and broad accessibility of Next Generation Sequencing (NGS) in cancer management. The project tackles the 3 main hurdles in the interpretation of cancer mutations: it is not systematic, it deals with a majority of variants of unknown significance and it fails to empower patients.The interpretation of tumor genomic data relies on the work of experts reviewing scattered databases and resources, in a time-consuming process that may lead to suboptimal clinical decisions. CGI-clinics will systematize the interpretation process by integrating relevant public and private databases hospitals in a one-stop shop tool, with the possibility to organize virtual molecular tumor boards co-facilitated by reference hospitals. Project will have three phases: a setup (assess needs), validation (pilot with the 9 clinical partners) and replication (30 hospitals across EU). It will enable democratization of genomic data interpretation (independent of their size, resources and profiling technology) and provide health economics validation.Relying on a systematic automatic learning platform, GCI-Clinics will increase the share of interpretable variants in tumors (from the current 9-12% to at least 50%), and features that constitute biomarkers of drug response. The interpretation process is complex for most cancer patients, alienating them from knowledge of their illness. CGI-Clinics will build eduCGI, an app to help them understand the information gained through interpretation of their tumors, facilitating informed discussions with clinicians and sharing their data
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'HOCHLASTDISPERSIONSREAKTORSYSTEME ZUR MIKROBIOLOGISCHEN INDUSTRIE-, KOMMUNAL- UN D LANDWIRTSCHAFTLICHEN ABWASSER - UND ABLUFTREINIGUNG' (BIODISPERSIONSYSTEMS).

assistant: **Concept**

Use of modular and upscalable high performance dispersion reactor systems for an optimized wastewater and air pollution treatment in the following fields:  - industry (industrial wastewaters; partial flow treatment on waterpolluting pro cess units)  - municipal wastewater treatment (improvements for existing installations and de centralized new treatment units)  - agriculture (liquid manure treatment at different kinds of animal farms with s imultaneous air pollution treatment) International techn
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Wafer scale Integration of Photonics and Electronics' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The WIPE project aims at developing hybrid electronic-photonic chips as a key enabling technology for data transmission purposes. It aims at bringing photonics to a new level by developing a concept that can be well industrialised. This sustains EU leadership in photonics, as is the ambition of the work program.   A new wafer-scale technology will thus be developed for direct and intimate attachment of III-V Indium-Phosphide (InP) photonic integrated circuits (PICs) and BiCMOS electronic chips (ICs). The ICs contain the driver, receiver andcontrol electronics for the PIC and enable direct connection to polymer optical waveguides. This technology of ‘wafer scale heterogeneous integration’ enables high-performance and high-density photonic-electronic (photronic) modules are created having a lower energy consumption, lower packaging complexity and lower cost compared to modules using more traditional interconnection techniques like wire bonding and laser welding of fibre connections. Next to the new bonding technology, an integrated module design technology is developed for efficient co-design of hybrid photonic and electronic modules. A library consisting of photonic/electronic standard modules, is created leveraging the process design kits (PDKs) of the most important European foundries of photonic chips in combination with a powerful BiCMOS. These tools are of significantimportance to industry, since they offer photronic module designers a standardised approach that highly facilitates the module design for SMEs and affordable manufacturing by photonic and electronic foundries. The WIPE approach will be proven by showing the feasibility of a 400Gb/s transceiver for data centre application.