RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'European Network Linking Informatics and Genomics of Helper T cells in Tissues' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

ENLIGHT-TEN+ is a European Network Linking Informatics and Genomics of Helper T cells in Tissues: A crucial missing link in our current research environment is the lack of qualified individuals who possess the immunology skills to recognise and define important scientific questions amenable to -omics approaches, and also the bioinformatic expertise to interrogate and interpret the resulting Big Data appropriately. Thus, our mission is to provide cross-disciplinary training for a new generation of enthusiastic researchers who have in-depth understanding of T cell immunology and are also capable to handle large datasets. Our network of 15 beneficiaries from 10 European countries combines expertise on T cell biology with state-of-the-art technologies generating Big Data, cutting-edge bioinformatic tools including artificial intelligence, preclinical models and samples from patient cohorts. ENLIGHT-TEN+ will identify microenvironmental factors shaping the functional properties of tissue-resident T cells, which offer important therapeutic potential in various human autoimmune diseases, making them a key target for pharmaceutical companies. 15 early-stage researchers (ESRs) will be empowered to push our knowledge of tissue-resident T cells beyond the state-of-the-art which will enable the identification of novel biomarkers and support the development of advanced therapeutic concepts. The generation of Big Data is an emerging and challenging field, and there is high demand in both the academic and industrial sector for researchers to be able to analyse, integrate and exploit this rich source of information. ENLIGHT-TEN+ will combine individual strengths of innovative laboratories and enterprises from complementary disciplines to provide unique interdisciplinary training as an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Reduction of nematicide use by introducing 2nd generation resistance genes in major european crops' (1994-1998) under Fourth Framework.

assistant: **Objectives**

Plant pathogenic nematodes form one of the most serious threats to modern agricultural practice. Almost all major crop species can be attacked by nematodes, and the losses in European potato and sugar beet production already exceed 110.000 kecu per year. Nematode control relies heavily on the use of highly toxic pesticides, resulting in the application by the European farmers of an estimated 10.000 Tons of nematicides (active compounds) each year. This practice forms an increasing burden to the environment.  The overall objectives of this project are: Increasing the natural resistance in major european crops against nematodes. - The isolation of a set of plant genes, referred to as 'second generation resistance genes', which will be used to endow sugar beet and potato varieties with resistance against plant pathogenic nematodes. Reduction in the use of pesticides in Europe, as well as to a lowering of the production costs for the farmers The obtained natural plant genes will have a superior performance compared to already available resistance genes, giving a durable resistance against a wide spectrum of pathogenic nematodes. Also, detailed knowledge about the way plants defend themselves against pathogens will be gathered, which will help to safeguard the successful introduction of the isolated genes into modern agriculture.  In the framework of the EC-AIR programme, our partnership (project AIR2-CT93-1206) recently succeeded in the cloning of the first nematode resistance gene from a plant species (Cai et al. (1997) Science 275, pp.832-834). This gene, the Hsl gene from sugar beet, now will be used to isolate the second generation resistance genes from the defence pathways that plants use to protect themselves against pathogenic nematodes. 1. Sugar beet, tomato and Ara
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Training Network for Monte Carlo Event Generators for LHC Physics' to be submitted under Seventh Framework.

assistant: **Abstract**

We propose a multi-site ITN consisting of 8 Full and 3 Associated Partners that will deliver a total of 500 ESR-months of training in the physics and techniques of Monte Carlo event generators to a total of at least 15 long-term and 40 short-term appointed researchers.Monte Carlo event generators are central to high energy particle physics. They are used by almost all experimental collaborations to plan their experiments and analyze their data, and by theorists to simulate the complex final states of the fundamental interactions that may signal new physics. We intend to build on the success of our RTN MCnet, by creating an ITN incorporating all the authors of current general purpose event generators, with the main purposes of:(a) training a large section of our user base, using annual schools on the physics and techniques of event generators and short-term residencies of Early Stage Researchers as a conduit for transfer of knowledge to the wider community;(b) training the next generation of event generator authors through a significant number of dedicated studentships in our research groups;(c) providing broader training in transferable skills through our research, through dedicated training in entrepreneurship and employability and through secondments to private sector partners.We will achieve these training objectives both through dedicated activities and through our outreach and research activities:(d) enhancing the visibility of particle physics in the wider community by specific outreach projects using event generators to visualize current particle physics research;(e) developing and supporting the new generation of event generators intended for use throughout the LHC data analysis era and beyond;(f) playing a central role in the analysis of LHC data and the discov
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Thermal Magnetic Resonance-based Ablation Cancer Therapy' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The MR-ACT project will develop Thermal Magnetic Resonance-based Ablation Cancer Therapy, a groundbreaking non-invasive approach that eliminates the need for invasive needle electrodes or fibre optic Laser probes in cancer ablation procedures. Building upon innovations from our ERC Advanced Grant ThermalMR, we will advance our proprietary high-density radiofrequency (RF) applicator technology to achieve ablative temperatures (>60°C) for tumour tissue destruction while maintaining millimetre-precision targeting and comprehensive MRI-based monitoring. Current radiofrequency or laser ablation approaches require invasive needle or fibre optic probe insertion, causing collateral damage, risking tumour seeding, limiting treatment to accessible anatomical locations, and increasing healthcare costs through hospitalization requirements. MR-ACT addresses these limitations by integrating diagnostic imaging, thermal treatment, temperature measurement and therapy monitoring in a single device without physical penetration of the body. This 18-month project will systematically refine the RF applicator technology for ablation temperatures, validate performance in anthropomorphic phantoms mimicking clinical scenarios, develop comprehensive IP protection and regulatory strategies, analyse market opportunities, and create a detailed commercialization roadmap. The technology enables treatment of previously inaccessible tumours, reduces procedural complexity, potentially enables outpatient treatment workflows, and improves patient experience while reducing healthcare costs. MR-ACT represents a high-risk, high-gain opportunity to fundamentally transform cancer treatment approaches. Our innovative non-invasive ablation technology could expand treatment options for patients with limited altern
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Rethinking Textiles' to be submitted under Seventh Framework.

assistant: **Abstract**

Rethinking Textiles is a two-year collaboration between Dr Barbara Hahn of Texas Tech University and Prof Regina Lee Blaszczyk at the University of Leeds to launch an effort to recontextualize the history of the British Industrial Revolution. The British mechanization of textile production is a crucial case for understanding the relationship between technological change and economic growth, but with few exceptions, the topic has long been dominated by economic historians concerned to explain change at the macroeconomic level. Rethinking Textiles is an example of micro-history, enriching the story of the Industrial Revolution with greater specificity about particular people, technologies, and products. It places the Industrial Revolution in an exciting new context, drawing on the history of technology, the history of consumption, and the history of design to develop a new narrative history of British industrialization as a global phenomenon shaped by cultural, social, and material variables with remarkable parallels to the Digital Age.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'A GRID-BASED e-INFRASTRUCTURE FOR DATA ARCHIVING/COMMUNICATION AND COMPUTATIONALLY INTENSIVE APPLICATIONS IN THE MEDICAL SCIENCES', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Aim of this proposal is to deploy e-Infrastructures (EC-funded MammoGrid and AddNeuroMed's NeuBase) to enable the European neuroscience community to carry out research required for the pressing study of degenerative brain diseases to build a new user-friendly Grid-based research e-Infrastructure (neuGRID), where the collection/archiving of large amounts of imaging data is paired with computationally intensive data analyses. This proposal will initially provide neuroscientists with the capability to identify neurodegenerative disease markers through the analysis of 3D magnetic resonance brain images via the provision of sets of distributed medical and Grid services and later to provide a general, expandable infrastructure of services for other medical applications. neuGRID will be compliant with acknowledged EU and international standards regarding data collection, data management, and Grid construction. Of the two deployed infrastructure, MammoGrid will provide knowledge related to the middleware and upperware that will allow applications to talk to the Grid, and AddNeuroMed that related to the collection/archiving/retrieval of multicentre clinical data, biomedical images and computerized image analysis. Key research challenges will be: the gridification of algorithm pipelines for brain image analysis, the development of a mid-layer of services between user-facing and grid-facing services to make the infrastructure expandable to a number of algorithm pipelines, and testing and validation of the prototype infrastructure. neuGRID aims to become the Google for Brain Imaging", providing a centrally-managed, easy-to-use set of tools with which scientists can perform analyses and collaborate."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Orbital Free Density Functional Theory: insights from quantum chemistry and atomic physics' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

This proposal aims to put me at the forefront of research in two related domains: quantum chemistry and atomic physics. These domains have the same origin in finding solutions to the Schrödinger equation. Although the methods in both domains stem from the same ab initio approach, they departed from their common ground and developed methods specific to their problems. A few decades ago a revolutionary method came to quantum chemistry: Density Functional Theory (DFT). In this theory the electronic density function replaces the traditional, more complicated wave function to describe the electronic structure of molecules. The implications for computational chemistry have been astounding. The successful development of density functionals to evaluate a system's energy, has made DFT a powerful tool, with applications from bio-chemistry to chemical reactivity. It has become the most popular quantum chemical tool. Today's calculations typically use the Kohn-Sham method which implies the introduction of orbitals, departing from the original spirit of the density-only theory. Motivated by their computational attractiveness (linear scaling, no orthonormalization,no Brillouin zone sampling) researchers have taken up the challenge to design orbital free functionals. This project aims towards the construction and evaluation of such orbital free functionals. Since DFT approaches, remarkably, never found their way to atomic physics, where their potential is evident and since ab initio methods from atomic physics still provide the highest quality density functions (corresponding to an eigenstate), the objectives in this project propose a synergy of concepts, methods and fundamental aspects in both fields. For the successful execution of this interdisciplinary proposal, milestones have be
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'The challenge of malaria in the post genomic era'.

assistant: **Objectives**

The genomes of the malaria parasite and its hosts have been recently completed. This programme is designed to meet the challenge of how best to exploit this information to attain a thorough understanding of the biology of the parasite and the interaction between the parasite and its hosts. The innovative exploitation of post genomic tools will advance the quest for new methods to control parasite proliferation, the pathophysiology of the disease and, possibly, the mosquito vector, providing new clinical applications and benefiting public health.The MalParTraining EST programme proposes to create by education and training a cadre of young, highly professional, creative and broad-minded thinkers through collaborative projects. They will acquire a wide range of research skills in areas ranging from bioinformatics and molecular biology through biophysics, protein biochemistry, cell biology and immunology. The research programme is the result of collaborations between leading groups of malaria research in major European institutions, most of them being currently engaged in the European Network of Excellence Biology and Pathology of the Malaria Parasite". First class advanced training through courses, workshops and annual meetings will provide the fellows with an unrivalled start to their future careers.The consortium aims to promote the exchange of ideas, cutting edge technologies, skills and concepts, developing a shared vision, a sense of identity and "lan" in the new and emerging Europe of malaria research. The programme will be dynamic, and will also promote the training and education of a new generation of scientists from malaria endemic areas, equipping them to establish high quality malaria research programmes in their own countries. Its ultimate goal is to establish
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'EMSO implementation and operation: DEVelopment of instrument module' (EMSODEV) targeting Horizon 2020.

assistant: **Abstract**

The EMSODEV general objective is to catalyse the full operations of the EMSO distributed Research Infrastructure, through the development and deployment of the EMSO Generic Instrument Module (EGIM). EGIM will provide accurate, consistent, comparable, long-term measurements of ocean parameters, which are key to addressing urgent societal and scientific challenges (e.g. climate change and hazards). This will lead to an increased interoperability of EMSO nodes and to the common collection of ocean essential variable time series. The specific objectives are: (1) to design and implement a state-of-the-art, standardized multidisciplinary EGIM, a common, harmonized, observation system; (2) to fully test, calibrate, validate and assess the effectiveness of this innovative module in order to ensure its maximum quality, long-term durability, and reliability; (3) to strengthen the data management and delivery backbone of the EMSO RI; this will require a coordinated approach to data capture, archiving, management, and delivery, in turn spurring the development of a wide range of data products and services; (4) to promote the uptake of the project results and public-private partnerships establishing links with industry and SMEs for technology transfer. These objectives will be achieved through: (a) Research & Innovation activities focused on the design, development, test, replication and deployment of EGIMs at EMSO nodes and data management system implementation; (b) Communication, dissemination and exploitation activities aimed at disseminating and facilitating the uptake of the project results, and setting up activities to increase the innovation potential of EMSODEV technological output, and to explore EGIM commercialization.All these activities are in line with those listed in t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Enhanced patient safety by computational Modelling from clinically available X-rays to minimise the risk of overload and instability for optimised function and joint Longevity'.

assistant: **Innovation**

Osteorthritis (OA) is a disabling disease, affecting the joints of 40% or more of the population over 60, resulting in a socioeconomic burden of €7b. per year in Germany alone. Joint surgery attempts to address the various disease stages, to either minimize the risk of early degeneration of the native joint, or to replace a fully degenerated joint, with well over 1,000,000 surgeries performed annually in the EU. Adequate joint function and longevity are the most important factors that define success, yet at least 10% of reconstructions fail within 10 years of surgery, and a large fraction of native joints progresses to early OA. The ensuing revision surgery is not only painful and stressful for the patient but also costly for the health care providers. Joint failure is a consequence of inadequate competence of the patient's musculoskeletal system, joint overload and instability, or their combination. Currently, surgeons rely on 2D static radiographs and their experience to plan the procedure. To prevent failures and improve outcome, key facts on the mechanical conditions of the joint need to be available to the surgeon. By implementing refined image reconstruction, biomechanical modelling and analysis tools, MXL will make the dynamic joint loading and stability accessible for the planning of joint surgery in every case. Based on this technology, MXL safeguards the patient by supporting the surgeon to decide when to operate, which procedure to use, and which key aspects to address to reduce the failure rate and improve the functional outcome of joint surgery. Therefore, we will develop an ICT based planning environment that provides the surgeon with quantitative information on the patient's anatomy, the competence of the soft and hard tissues, and integrates them within