RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Non-covalent photoresponsive tags for photoacoustic imaging: Giving voice to living matter' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Visualizing the complexity of living matter non-invasively and with high-resolution represents an indispensable element for progress in science. Unresolved issues as the individuation of early-stage cancers, or the spatial organization of the roots microbiomes, can benefit from advancements in photoacoustic imaging (PAI). This appealing technology combines the benefits of light as input and ultrasounds as output, offering a compelling combination of good resolution, high penetration depth, and non-invasiveness. However, PAI is not suitable to study multicomponent living systems because current strategies operate with simple probe-detector setups. With SmartSAST (Smart Sound-activated Absorption Shifting Tags), I propose to enable modularity and multiplexing through the development of photoacoustic probes based on protein tags that non-covalently bind with photoresponsive organic chromophores named sonogens. The supramolecular nature of SmartSAST ensures great modularity as the sonogens can be easily refreshed or substituted. The change in optical properties of the probes upon assembly guarantees great contrast against the background. Finally, via rationally designing photo-isomerizable sonogens that bind the protein just in a specific isomeric form, SmartSAST imparts an unprecedented level of control in PAI. Upon photo-modulating the supramolecular dynamics of these probes and extracting their kinetic signatures, dynamic contrast and multiplexing will be achieved with high spatial resolution. SmartSAST project aims to develop a fully operative technology based on new fundamentals bases. The project includes the synthesis of sonogens, the engineering of protein tags, the thermokinetic and photochemical characterization of the probes and their application in PAI. This new
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Power through Attraction: British, Greek and Turkish Cultural Diplomacy in Cyprus, 1945-1974'.

assistant: **Objectives**

CuDiCy will investigate the cultural diplomacy (CD) of three states: the UK, Greece and Turkey, as it was practiced in Cyprus between 1945 and 1974. The action will be conducted by Dr. Maria Hadjiathanasiou, at the University of Nicosia (Cyprus), under the supervision of Hubert Faustmann, Professor of History and Political Science at the Department of Politics and Governance. Τhe action includes Secondments at the Embassy of Greece in Nicosia and, at the British Council in London. Timely and relevant, CuDiCy aspires to set a new paradigm in the growing field of CD, by becoming the study model for an innovative approach towards the exploration of external cultural influence in countries which accommodate ethnically diverse populations, for example Syria and Lebanon. It will contribute to the discussion about the conceptualisation of power, politics, authority and governance and, on the formation and transformation of identity. CuDiCy will achieve this by tracing and analysing the ways state and non-state cultural actors influenced the progress of events in Cyprus, from the end of the Second World War to the Turkish invasion. Time, location, concept and structure will be used as critical determinants to consider CD’s role. The methodology is crucial to CuDiCy’s main objective which is to expose the diverse and complicated functions, actions, visions and interpretations of what constituted CD during this period, to understand what its aim was, and to investigate how and if it accomplished its tasks. CuDiCy has a strong cross-sectoral multidisciplinary focus, involving the fields of History, IR, Political Science and the Humanities. It includes both the transfer of knowledge to the host institution and the training of the candidate in new methodologies and theoretical conce
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Gentlemen and Caballeros: a transnational analysis of nineteenth-century masculine honourability' (MASChonourability) under Horizon Europe.

assistant: **Objectives**

This pioneering research takes a unique approach to analyse the male gender identity of the upper and middle classes in Spain, Cuba, Ireland, and England during the nineteenth century. The project proposes a comparative study of male honour and its associated practices among the dominant classes in these four countries. The concept of honour was a powerful symbol of respectable masculinity, encompassing moral virtue, social and political precedence, the mandates of self-control for men, patriarchal power in the family, and legitimate use of violence. The analysis of honour thus provides an exceptional means of understanding the normative masculinity of the social elite. This project will investigate a little-explored topic by historiography, the shared and distinguishing aspects that defined the manliness of the self-appointed gentlemen (in England and Ireland) and “caballeros” (in Spain and Cuba) relying on a transnational approach. So far, research has analysed male honour in each nation separately, without considering enough the nuances that defined it in each territory. Moreover, how the gentlemen of these countries mutually aligned themselves as equals in honour and respectability has also yet to be studied. Additionally, the issue of “race” has not been sufficiently considered in previous studies on elite male honour. With its interdisciplinary approach, this project aims to analyse all these crucial aspects to complicate our understanding of middle and upper-class masculinity in the nineteenth century, along with the overall gender relations and the incumbent political and social context. In this way, we will gain a deeper understanding of the structural nature and historical roots of the violent and discriminatory practices based on gender, race, and class that
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'In vivo analysis of neuromuscular junction stability in zebrafish models of amyotrophic lateral sclerosis' (NMJALS) under Horizon 2020.

assistant: **Objectives**

Amyotrophic lateral sclerosis (ALS) is a late onset, lethal neurodegenerative disease of motor neurons that affects about 2 in 100,000 individuals per year. Different genetic mutations have been described in patients, but the genes involved seem unrelated and the causes of the disease appear complex and are still largely not understood. Of relevance, the destabilisation of neuromuscular junctions (NMJ) may be an early event, preceding neuronal death, making them an interesting therapeutic target to slow down disease progression. The goal of the study is to characterise the molecular organisation and dynamics of NMJ, in particular of cell adhesion molecules, in order to understand the mechanisms of maintenance of NMJ by analysing defects in their organisation in ALS contexts. Technically, we plan to combine neuron biology, quantitative cell biology and computational tools to reach a precise molecular understanding of the dynamic equilibrium of NMJ in zebrafish, an excellent vertebrate model for live imaging. We will develop innovative methods of super-resolution microscopy and of quantification of protein turnover using a fluorescent molecular clock. This precise molecular characterisation of the NMJ will allow detecting subtle early changes in the NMJ that occur before neuronal degeneration starts, in fish carrying mutations described in ALS patients. The project will lead to the identification of key proteins for NMJ stabilisation and enable the analysis of regulatory elements of this stability, especially the cytoskeleton. The innovative multidisciplinary approach of this study will unravel early modifications in the organisation of the NMJ preceding neuronal degeneration in ALS contexts. It will point out key proteins of NMJ maintenance constituting new targets for t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Support the coordination of cities’ activities via the Green Digital Charter' (GuiDanCe) targeting Horizon 2020.

assistant: **Abstract**

The Green Digital Charter is a EUROCITIES response, initiated by Clicks and Links Ltd and the City of Manchester, as part of a ‘Greenshift’ initiative. It has been realised through the work of the EUROCITIES Knowledge Society Forum (KSF) Working Group on ICT for Energy Efficiency, led by the City of Manchester. It was built on ICT-enabled sustainability initiatives like ""Smart 2020,"" with Global e-sustainability initiative and the Climate Group, and ""ICT4EE"" with the European Commission.From September 2011 to May 2014, European Commission awarded the FP7-NiCE project grant to provide a platform for action based on the Green Digital Charter. Following the first five years of promoting and working with the Green Digital Charter as well as the conclusion of NiCE project, GuiDanCe will build on the outcomes of NiCE and address the identified challenges that need to be further tackled.The aim of GuiDanCe project is “to provide GuiDanCe and support cities’ activities towards their Green Digital charter commitments so that they eventually take ownership of the Charter”.The project will work for three main objectives:1.Strengthen the engagement of GDC signatories to create a club of cities that work together towards their GDC commitments2.Improve existing tools and services and their impact to GDC signatories3.Promote GDC signatories’ activities in and outside the EUThe GuiDanCe project addresses the work programme topic “Support the coordination of cities' activities via the Green Digital Charter” and will be coordinated by EUROCITIES, a network of over 140 major European cities.""


**Keywords:** Green Digital Charter, ICT, energy efficiency, smart cities, EU-China, cities
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Setting a standard for personal digital sperm analysis' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

QS Mobile is a novel clip-on device for smartphones for male sperm analysis. QS Mobile combines microfluidics technology, compact optics & advanced video image analysis to make sperm tests automated, removing the manual labour errors & providing precision & reliability levels comparable to labs. QS Mobile is the only solution that that covers all three types of sperm measurements required by WHO— concentration, different motility classes & spermatozoa morphology analysis. QS Mobile addresses the problem of time-consuming, inconvenient and not fully standardized tests of male infertility. Male infertility tests are currently performed exclusively in labs, and it takes several visits & several days to get a result. With QS Mobile male fertility tests can be carried out at home quickly, accurately & more cheaply than in the lab. It is targeted at men who are planning children, undergoing fertility treatments or interested to change their habits to increase their chances of conception. QS Mobile can also be used by hospitals that either don’t have or cannot afford a dedicated fertility lab.QS Mobile is developed by Biophos—a Swiss SME that commercialized QualiSperm—an industry-recognized advanced semen analysis technology installed in 15+ labs in Germany & Switzerland & performing 20,000+ sperm quality tests per year.With QS Mobile, Biophos intends to disrupt the market of male fertility tests by fully automating them and giving the affordable & reliable testing device to the men who need it, so that they can carry out the tests in privacy & comfort of their homes. By 2027 Biophos intends to serve 15-20% of total market with €217.2-289.6m annual revenues globally.In this phase 1 feasibility study Biophos will validated the B2C go-to-market approach & develop a value proposi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'ATtracting and connecting innovation ecosystem actors for international co-investments in advanced TRACTION of deep-tech companies from Wielkopolska, Lithuania and Andalusia.', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Assumptions:- There are many incubation and acceleration programmes in ‘modest’ and ‘moderate’ innovation ecosystems, however there is much fewer investors operating there as well the volume of capital available and actors of innovation ecosystems are not well connected- The potential investors (capital and industry) need relationships of trust with locally-based co-investors of smaller scale that would help them with the local deal flow as well as regulation guidance- The start-up ecosystems all over the world are oriented toward speed exits, which does not favour deep-tech start-ups, that need more time for development- Even the vibrant start-up hubs in Europe have problems in creation of deep-tech deal flowObjectives of atTRACTION:1. To connect the ecosystems in Wielkopolska, Lithuania and Andalusia  to strong innovation networks of Germany and France and:- stimulate cross-fertilisation effects through best practice sharing and learning by cooperation- syndicate a curated pipeline and portfolio of companies at different funding stages to create joint, syndicated, thematically focused deal flows that attract international investors- boost existing support programmes of business acceleration providers 2. To create investment opportunities for society-relevant deep-tech solutions: twin transition and health-tech, IOT& AI for social challengesProject idea:- Attraction and connection of existing acceleration initiatives and investment networks from the participating areas- Development of durable international relationships through concrete actions, i.e. pilot acceleration programs oriented on society needs solutions stemming from R&D- Joint activities increasing the level of trust among investors and founders from less connected ecosystems- Create syndicated, internationa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Cellular and molecular mechanisms of resistance artery remodelling' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Objectives:The aim of the project is to determine the processes which lead to abnormal structure of resistance vessels in hypertension. The project is based on the following hypotheses.  -That remodelling of resistance vessels can be initiated by the mechanical stress caused by transmural pressure, which in turn initiates growth processes similar to those initiated by growth factors such as PDGF.  -That the remodelling process is associated with the expression of the extracellular matrix (ECM) proteins fibronectin, thrombospondin, tenascin, and laminin, as well as decreased expression of heparan sulphate proteoglycans.  -That eutrophic remodelling (remodelling without net growth) can be initiated following activation with noradrenaline, but hypertrophic remodelling with angiotensin II.  -That eutrophic remodelling is due to a combination of integrin-mediated redistribution of existing material, as well as synthesis and apoptosis.A major factor in long term cardiovascular homeostasis is how the vasculature structure adapts (remodels) in response to pressure, flow, and hormonal activation. Development of drugs for treatment of diseases involving changesin vascular structure (hypertension, heart failure) depends crucially on understanding these mechanisms. A previous project (EURAD) organized by the present applicant under BIOMED-I has demonstrated that in essential hypertension the vessels responsible for determining blood pressure (resistance vessels, e.g. small arteries and arterioles) are subject to 'eutrophic remodelling', a rearrangement of material. In contrast, we demonstrated hypertrophy (increase in vessel volume) in resistance vessels of patients with certain forms of secondary hypertension. Furthermore, it was shown that some, but not all, forms of antihyperten
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Symmetry breaking in string theory' (1998-2002) under Fifth Framework.

assistant: **Objectives**

The project that I propose consists in the study of symmetry breaking in string theory and related field theories with extra dimensions. This is one of the most challenging aspects of the program of embedding the standard models in string theory, which has definitely singled out as the most promising candidate for a fundamental and unified theory of all interactions. The main objective is to provide novel possibilities in this respect and investigate new or little studied scenarios for the symmetry breaking occurring along the way from the fundamental string scale down to scales accessible to present and future experiments; symmetries of primary importance in this respect are supersymmetry, gauge symmetries, and possibly internal flavor symmetries. The content is articulated over the following main points. First, a broad investigation of new possibilities to construct string models implementing symmetry breaking at the compactiflcation scale, for instance through the Scherk-Schwarz mechanism, Wilson lines or the presence of branes, and possible connections between them. Second, a deeper study of the nature of symmetry breaking by compactification and the possibility of a dynamical implementation of it, adressing in particular the issue of classical and quantum stability. Third, exploit intermediate examples of string-inspired higher-dimensional field theories, modeling in a realistic way symmetry breaking, to identify phenomenologically promising string embeddings.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'European Transport Research Area International cooperation activities' (EUTRAIN).

assistant: **Concept**

In the field of Transport research, the European Union as well as other major national, federal or regional entities of “global” importance such as the U.S., Japan, Australia, South America, India, China, and others are buffeted by common transport related problems and challenges. International Cooperation in Transport research is becoming therefore an increasing priority aiming, primarily, at creating “critical mass” in moving collaboratively to solve critical 21st century transportation challenges. The main idea and objective is to establish – through international cooperation in transport research - the free circulation of specialized knowledge, experience and know how in facing transport problems and challenges and create through collaboration the conditions for more “breakthrough” research and achievements that would otherwise require more time and resources if faced individually and separately. As the European Transport Research Area (ERA-T) takes shape and strength, international transport research collaboration can both help its further strengthening and internal cohesion as well as boost Europe’s competitiveness in the global economy. The EUTRAIN proposal seeks to put forward a framework for such international cooperation in Transport research between the European Transport Research Area (ERA-T) and other regions, in order to ease existing barriers and limiting factors for such collaboration. It is also of major interest to try and achieve, within international research collaboration, an increased focus on human resources and creating the next generation of “global” researchers. EUTRAIN will build upon the existing experience and know-how in this field - that has been gained in recent years through specific actions of international cooperation as well as projec