RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Universal and Specific Properties of a Uniquely Human Competence. Tools to study language acquisition in early infancy: Brain and behavioural studies.' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Knowledge on functional-anatomical prerequisites to acquire language has grown exponentially due to the discovery of behavioural methods and the development of high resolution functional imaging tools. The latter link behaviour to physiological brain proce sses and define areas essential for the proficiency in a unique human competence: language. In adults, knowledge on cerebral processes mandatory for language competence has greatly improved. This rapidly increasing knowledge allows for the description of a model integrating behavioural and physiological findings of how the proficient speaker masters language. However, to understand the uniqueness of human language it is imperative to understand how human infants acquire syntax and how the child learns to ha ndle the more mysterious semantic properties of a specific language. Psycholinguists must acknowledge that acquisition begins at birth when some of the prosodic and phonological properties are already set. We must also explore how and when lexical and synt actic properties are learned and we have to address the question how signals from the infant brain allow for an extension of the adult functional anatomical findings to infants. Our consortium has sketched a series of studies to clarify these issues by int egrating psychologists, physiologists, linguists, and experts on brain imaging for a deeper understanding of the infants brain function. This multidisciplinary approach is chosen since an investigation of language in the infant necessitates modifications i n experimental design, data acquisition, and analysis. To unravel the human uniqueness we take the challenge to analyse signals from a rapidly developing brain, where plasticity is the rule rather than the exception. We aim at an understanding of language com
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Solid Preparedness And Resilience for Robust Operations during disaster Wilderness' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The SPARROW platform represents a pioneering solution for enhancing societal resilience and crisis management in the face of digital breakdowns. Employing a modular architecture encompassing data integration, simulation modeling, and a collaborative platform, SPARROW orchestrates large datasets and expert insights to create a dynamic digital twin of a city. This digital twin, visualized in 3D, becomes a robust testing ground for assessing vulnerabilities and preparing for diverse crisis scenarios. Through a participatory approach involving citizens, local authorities, and first responders, the platform fosters communication during breakdowns and bolsters preparedness against digital threats. SPARROW's innovative tools, including the Emergency Communication Mobile App (ECOMAPP), City Digital Twin (CITWIN), and the Dynamic Critical Asset Management Recommendation Engine (DYCAMARE), are co-designed with stakeholders to ensure user-friendly, effective, and ethically sound functionalities. The platform's impact extends across various sectors, from critical infrastructure managers optimizing maintenance to emergency responders utilizing a mobile 5G network (EMER-5G) for prioritized communication (ECOPRIM). In alignment with EU policies, SPARROW aims to enhance crisis communication, bridge gaps in digital breakdown preparedness, and contribute to a secure and resilient European way of life.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Preventing Therapy Resistance in Esophageal Cancer Using Advanced Models and Molecular Signatures' in the context of a Horizon Europe call.

assistant: **Objectives**

In 2035, cancer will have become the leading cause of death in the EU. In line with the Horizon Europe Plan to Beat Cancer, one of the five Horizon Missions, the PRESSURE network sets out to train 10 future experts who will push the development and clinical implementation of effective treatments and policies against therapy resistance in cancer. This innovative project will specifically focus on esophageal adenocarcinoma as one of the most complex cancer types in terms of resistance, and most urgently in need of novel solutions. Prominent factors that contribute to the poor outcome of esophageal cancer are a high degree of acquired resistance, and heterogeneous responses to the available therapies. Despite this knowledge, there are currently no consensus treatments for this disease in the EU, and there is insufficient awareness of the need for a unified low-risk treatment strategy. Numerous different regimens are currently given across the continent, and as a result highly divergent outcomes of EAC are observed. This adds to Cancer Inequalities in Europe. To address this, PRESSURE researchers will receive exhaustive intersectoral training, and deliver high-quality knowledge, across the entire value chain: Epidemiology, imaging, patient-derived model systems, resistance mechanisms, diagnostics, patient-centricity, valorization, and treatment. By receiving this diverse training, the ESRs will become next generation thinkers and problem-solvers, and will be able to deliver creative contributions to all fields involved in the combatting of cancer with unique solutions applicable in the clinic and society. This combination of complementary research expertise and rich training is not currently offered in an EU network.


**Keywords:** therapy resistance, esophageal adenocarci
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Beyond 1M Genomes' (B1MG).

assistant: **Concept**

The Beyond 1 Million Genomes (B1MG) consortium will establish the support and coordination structure for the European 1+ Million Genomes initiative (1+MG), which is based upon the commitment of 20 European Member States and Norway that have signed the Declaration ‘Towards access to at least 1 million sequenced genomes in the EU by 2022’. Collectively, these countries have committed to establish a cross-border federated network of national genome collections associated with phenotypic data, consented for advancing health and medicine practices across Europe. Europe is uniquely placed to take on this challenge and position itself as a global leader in this field.B1MG will go ‘beyond’ the 1M genome target and ‘beyond’ the 20 signatory countries. The project will collaborate with an array of international initiatives and consult a range of stakeholders to support the creation of a pan-European genome-based health data infrastructure, encompassing data quality and exchange standards, access protocols and legal guidance. Recommendations will be translated to a B1MG maturity level model that provides concrete guidance on the steps required to implement personalised medicine, a healthcare approach that takes into account a person’s genetic make-up, at local, regional and national-scale. Personalised medicine is expected to bring significant socio-economic benefits, including more efficient national health systems. Faster and more accurate diagnosis, the development of pharmacogenomics and advancement of preventative medicine will lead to better health, quality of life of patients and increased life expectancy. This will be captured in a methodology for economic evaluation, forming the basis of future business-cases for implementation in the health sector.


**Keywords:** 1+MG,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Quantum-Statistical Methods for Nuclear Singlet States in Complex Fluids' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) are supremely important techniques with widespread applications in chemistry, physics and medicine. NMR methodology has until recently been limited by the time constant T1 for the decay of nuclear spin magnetization back to thermal equilibrium. Long-lived nuclear singlet states (LLS) have been shown to overcome this limit with a decay constant TLLS that may be two orders of magnitude longer than T1. However, so far mostly ideal systems have been studied in the LLS context, involving simple solvents and oxygen and other paramagnetic molecules removed. This is far from the conditions in many potential applications of MRI and/or materials research, and it is not clear how LLS performs in environments such as complex fluids or biological matter. To overcome this limitation, the proposed project is to develop state-of-the-art quantum-statistical simulation methodology toolbox to model TLLS in complex fluids (lipid/water phases). The project builds on the experience of the research fellow in LLS and computational engineering combined with quantum-chemical, molecular simulation, and experimental expertise of the host institution. Methodology for the essential but challenging quadrupole and paramagnetic spin relaxation enhancement will be developed for LLS. Machine learning techniques will overcome the excessive computational burden of very many quantum-chemical calculations needed in conventional computational relaxation studies.The simulated TLLS will provide a general understanding of the applicability of LLS at the microscopic level, for colloidal systems. The theoretical understanding will guide the development of LLS in materials research and MRI. Machine learning development will feed into the quantum
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Label-free single-molecule detection of complex biomolecule interactions in free motion'.

assistant: **Objectives**

Dysregulated interactions between biomolecules can lead to changes in cell signalling and gene expression, both common drivers of human disease. A detailed understanding of these interactions is vital for drug development, often targeting such interactions for therapeutic effects. In this project, I aim to develop an optical microscopy tool to observe interactions of highly diverse biomolecules in terms of e.g. weight or size, in real-time on a single-molecule level without the use of labels or immobilization, which limits many current established methods. This will allow the study of dynamic interactions between complex biomolecules of varying sizes and with a wide range of properties. The tool will be capable of researching various biological systems that are not easily accessible by established methods. This could contribute to breakthroughs in the research of severe diseases such as diabetes mellitus, Alzheimer's, or Parkinson's disease.


**Keywords:** Nanofluidic scattering microscopy, nanofluidics, nanochannels, computer modelling, biomolecule interactions, ribosome-chaperone interactions, protein-free floating membrane interactions
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Dickens, Adaptation, and the Nineteenth-Century European Theatre' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

“Adapting Dickens” approaches the work of Charles Dickens from a fresh, dynamic, globally engaged perspective. The project considers adaptations—particularly dramatizations—of Dickens's novels as key sites for international cultural interaction in the nineteenth and early twentieth centuries. Adaptation to the stage transformed Dickens--Britain's emblematic national writer--into an international cultural commodity: the stage, a global network for cultural transactions, interpreted and circulated his work across Europe and the nineteenth-century colonial world. The research at the heart of the “Adapting Dickens” project views adaptations as expressions of critical interpretation of literary texts as they comment upon and translate them into new media, other languages, and for consumption by a wide array of audiences. The project draws upon the latest developments in adaptation theory and pedagogy, and it seeks to find fresh venues for researching Europe’s Dickens; new tools for locating, interpreting, and disseminating work on Dickens and the nineteenth-century theatre; and ways of communicating emerging ideas about Dickens, nineteenth-century Europe, literary adaptation, and cultural currency to audiences beyond the academy. The project will (1) ensure knowledge transfer to Europe and enhance and enrich both European literary and theatre studies;, (2) enhance pedagogical innovation via public performances, classroom outreach activities, web development, and a volume on teaching through adaptation; and (3) contribute to the Fellow’s professional development through web training, advanced language study, archival research in Europe, and the production of articles and a scholarly monograph.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'DNA extraction from ancient and modern maize samples and biochemical characterization of genes with key roles in domestication' under Seventh Framework.

assistant: **Concept**

The domestication of maize (Zea mays ssp. mays) occurred through the selection of a suite of phenotypic characteristics over the last 7,000 years, ultimately resulting in the classic cob-heavy crop that we today recognize as modern maize, markedly different from its grass-like ancestor, teosinte.This project involves the extraction of genetic information from archaeological maize samples spanning its domestication history followed by the selection of interesting targets for further biochemical characterization. I intend to look at key molecular switches that resulted in the sequential improvement of modern maize from the ancestral varieties.Such information is of highest interest for agricultural research as the ancient plants, including those disregarded by early farmers, can be the carriers of interesting molecular and phenotypic features for modern times. Of particular interest will be extinct protein isoforms with biochemical and/or cathartic properties that may be relevant for nutrition, resistance to pathogens or stress, or even involvement in metabolic pathways leading to the production of valuable metabolites of commercial interest. The spatiotemporal mapping of the samples can also potentially reveal important traits, such as the ability to adapt to environmental changes like climate change or water scarcity.This project is an example of truly multidisciplinary research: by combining the use of the latest sequencing technology with excellent biochemical expertise to explore invaluable collection of archeobiological material, this work will generate results that will have an impact in fields as disparate as archaeology and agricultural sciences. Furthermore, this IEF will allow me to complement my multidisciplinary theoretical training, based on computational ap
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'A Digital value chain Integration Traceability framework for process industries for Circularity and low Emissions by waste reduction and use of secondary raw materials' (DigInTraCE).

assistant: **Innovation**

DigInTraCE aims at the development of i)transparent and interoperableDecentralised Traceability platform using novel tracking, sensing and sorting techniques ii)Dynamically updated DPPschemes supporting certification and quality validation iii)AI based and decision making mechanisms for process and lifecycle optimisation iv)up-cycling, reuse and upgrade technologies for improved secondary raw materials use v)contribute to standardization, open and easy accessible data vi)business models creating new economic opportunities and learning resources for employees, promoting new digital skills and meeting regional social needs. The solutions are demonstrated in the sectors of a) Pulp & Paper focused in 2 cases: composite wood and furniture; and wood and Pulp & Paper and b) Chemicals focused in 2 cases: plastic parts from ICT equipment and automotive market; and polymers and textiles: in 4 countries, while composite wood case combines both the 2 main sectors.


**Keywords:** Circularity, Secondary raw materials, Waste, Traceability,  Digitalisation, Digital Product Passport, Industry, Low Emissions
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Seventh International Conference on X-Ray Lasers', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

X-ray lasers (XRLs) are presently the brightest source in the wavelength range comprised between a few nanometers and a few tens of nanometers; they are brighter by orders of magnitude than any other source. The XRL active medium is a hot and dense plasma generally produced by a high power infrared laser, although capillary discharge has shown to be able to produce amplifying plasmas. Population inversions are due to electron-ion collisions. Nevertheless, other pumping schemes, particularly in rapidly cooling plasmas, are investigated. Concurrently high-harmonic generation gives rise to short wave-length, coherent emissions. The optical properties of these sources make them attractive for a large number of applications in various fields of research and technology. Short wavelength and coherence, coupled with high brightness, are useful for high-resolution analysis of matter by X-UV microscopy, interferometry or holography.On the other hand, new types of interaction between X-UV radiation and matter can be realised owing to the XRL-high intensity: XRL-induced luminescence, X-UV multiphoton processes, quantum optics in the X-UV range, etc. The series of International Conferences on X-Ray Lasers" began in Aussois (France) in 1986. It has a 2-year periodicity.This meeting is the place where are shown and discussed progress of XRL research: collisional lasers and other inversion schemes, optical properties of XRL beams, alternative coherent X-ray sources (undulators, X-ray free electron lasers) and also applications experiments and utility of XRL for diverse purposes. It comprised about 30 invited and 30 contributed talks, and two poster sessions. Owing to the development of XRL applications, this meeting has an interdisciplinary character because present and potential XRL u
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Testing innovative strategies for clean urban transport for historic European cities'.

assistant: **Concept**

RENAISSANCE aims to develop a valid, reliable and integrated package of access and mobility measures for historic cities. These will make possible the rediscovery, preservation and enhancement of historic cities in Europe, together with the sustainable development of the local economy, to the benefit of visitors, residents and local business alike. RENAISSANCE brings together a group of historic/tourism cities across Europe that are in the vanguard of sustainable development.The RENAISSANCE cities have a strong reliance on heritage and tourism, which must marry environmental concerns, and sustainable access and mobility, with economic development. The partners face common problems: they are all historic cities with common layouts, and very valuable heritage to be preserved and enhanced. The partners also face unique local and regional challenges, including those brought about by social and economic integration within the EU. There is great added value in RENAISSANCE because the best practices that will be demonstrated will have resonance and relevance throughout the range of European Historic Cities.