RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Development of an efficient steganalysis framework for uncovering hidden data in digital media.' (UNCOVER).

assistant: **Concept**

Criminals and terrorists use more and more data hiding methods (steganography) for concealing incriminating information in innocent-looking digital media files such as images, video, audio, and text files. UNCOVERs main objective is to fill existing gaps in the ability of Law Enforcement Agencies (LEAs) for detecting the presence of such hidden information (i.e., steganalysis). To carry out a full investigation into criminal and terrorist activities, LEAs currently use available (commercial) tools to detect hidden information in collected digital media. However, these tools detect only a limited number of hiding methods, are slow, and offer no indication of confidence. Moreover, many commercial tools lag a decade behind the scientific state-of-the-art. The members of UNCOVER are committed to bridge these gaps and thus substantially increase the technological autonomy of LEAs in the field of digital media steganalysis. With its consortium of 22 partners including LEAs, forensic institutes, leading researchers working at universities and research institutions, as well as industrial companies, UNCOVER sets out to outperform available steganalysis solutions in terms of performance (number of detectable steganographic methods, detection accuracy), usability, operational needs, privacy protection, and chain-of-custody considerations. The developed detection and investigation tools will be integrated into a flexible and user-friendly platform. End-users play a key role throughout the project cycle: from proposal writing over analysis of user requirements and tools development through the final evaluation. In particular, regular feedback cycles with LEAs, forensics institutes and external stakeholders will ensure that the developed solutions can be integrated into the daily cri
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The Impact of Observational Learning on Brain and Behaviour Throughout the Lifespan' (2007-2013) under Seventh Framework.

assistant: **Objectives**

As humans, our ability to survive within a social world is facilitated by learning through observing others. As such, when learning tasks as simple as tying one’s shoes or as complex as performing heart surgery, we learn by watching from childhood through to old age. Many researchers from the behavioural and brain sciences suggest that observational and physical learning share common features. What remains unknown is how our brains and behaviour change when learning by observation across the lifespan, as well as how age impacts the effectiveness of observational learning. To address these questions, I measure the impact of observational learning on behaviour and brain activity among children, young adults, and older adults. The ultimate aim is to develop a means of identifying factors associated with observational learning success, which in turn will inform observation-based interventions used in education and therapeutic contexts. The most direct implication of the ‘Watch and Learn’ project is a better understanding of how we transform visual information to physical skills from childhood through to advanced age. More broadly, those who teach or rehabilitate motor skills in people of all ages stand to benefit from the project’s findings through an improved understanding of how observational learning compares to physical learning in terms of behavioural performance, and how quickly or effectively individuals of different ages may be expected to learn by observation. Outreach activities are targeted at educators who teach physical skills in schools and hospitals, with the aim that observational approaches may be optimized based on the results of this project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Sleep homeostasis in Caenorhabditis elegans' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The aim of my research is to unravel one of the biggest unresolved problems in neuroscience: the function of sleep. Sleep is an essential aspect of our lives, the importance of which appears clear in pathological conditions where its normal patterns are disrupted. Moreover, it is an evolutionary conserved phenomenon. It has been described and characterized at levels, ranging from behavioural to neural and molecular, in different animal species. Despite its conservation, pointing to a fundamental function in animal survival, the reason for sleep is still debated. Different hypotheses have been raised, such as the energy hypothesis, the synaptic homeostasis hypothesis, and the clearance hypothesis; there is evidence to support each. However, no conclusive agreement on the main reason why sleep evolved has been reached. This is mainly due to the difficulty in integrating the above-mentioned levels of characterization in a single model organism. I will overcome this limitation by studying sleep homeostasis in the nematode Caenorhabditis elegans. Since sleep is a global process spanning the entire brain, full understanding of its regulations requires investigation at levels ranging from molecular mechanisms in single cells to brain-wide network activity. This is currently achievable only in C. elegans, providing a small anatomically mapped nervous system, advanced genetic tools, and a novel whole-brain imaging approach with single-cell resolution that was developed in my host lab. I will leverage on this approach, as well as a new quantitative behavioural paradigm for sleep homeostasis in adult worms, to study the brain-wide effects of sleep deprivation. To unravel the essential function of sleep, I aim to:I: Characterize adult C. elegans sleep by quantitative behavioural an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Quantification of bioactive peptides by mass spectrometry - Applicability in drug discovery' (2002-2006) under Sixth Framework.

assistant: **Objectives**

The study of pharmacologically active peptides is central to the understanding of disease and to the development of novel therapies. It would be advantageous to monitor the fate of bioactive peptides following their administration or the modulation of endogenous factors (e.g. peptide hormones) affected by the administration of pharmacological agent. Measurement of administered compounds in plasma is a mature field. However, measurement of pharmacologically active peptides, such as Glucose-dependent insulinotropic peptide (GIP) and the melanocortin analogue Melanotan-II (MT-II) presents particular problems for quantitative mass spectrometry, including challenges from selectivity and sensitivity perspectives. Current approaches towards peptide quantification in biological fluids include immunoassays or uses of mass spectrometric techniques. Immunoassays, although sensitive, lack the necessary selectivity for distinction between peptide and metabolites. Modified molecules induced by metabolic transformations (e.g. N- or C-terminal truncation of the peptide) might not be differentiated by the antibody used in the assay, leading to cross-reactivity.However, although it is generally accepted that mass spectrometry is an ideal technique for the quantification of trace levels of analytes in biological fluids, immunological techniques are still characterized by better limits of detection. In this application we propose to contribute to the field of quantification of peptides by mass spectrometry by pursuing novel approaches on selective peptides for which limits of quantification have been previously established. If we succeed we will demonstrate the applicability of the approaches in vivo models.In the future our knowledge (improved mass spectrometric approaches) can be extende
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Clinical validation of a new diagnostic and monitoring PoC medical device based on quantification of biomarkers in tear fluids to improve the quality of eye health care', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Ocular diseases are not only relevant social, sanitary and economic issues, but also a growing market opportunity in an increasingly ageing population. Ophthalmology is a health care area where the availability of easy to use point of care (PoC) medical devices based on biomarkers is fundamental for improving patient vision care, reducing number and frequency of sick leave and disability due to visual problems and for getting a significant reduction of overcrowding of ophthalmology units at health systems. The use of medical devices able to detect and measure biomarkers in human samples in a fast and non-invasive method will allow the easy introduction of these systems at the doctor’s office, thus enabling diagnosis of diseases in an objective manner and accurately monitoring of treatments effectiveness to be introduced into the standard clinical protocols.The present project is aimed to the clinical validation and market introduction of a device previously developed for ocular surface diseases (OSDs), named Tear Monitor and focused on diagnosis and monitoring of the Dry Eye and inflammation by measuring biomarkers in tears. For this purpose, two European SMEs specialised on ophthalmology establish a collaborative partnership to joint their respective expertises in a complementary synergism to reach the objectives proposed.  Horus Pharma, a French pharmaceutical company, specialised on production, distribution and sales of pharmaceutical and biotech products for eye therapy and diagnostic; and Bioftalmik, a Spanish company specialised on biomarker discovery and development of medical devices for ophthalmology applications.This project is crucial for the economic growth and international expansion of both companies and constitutes the base for strategic development in th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Open Science Plan-Track-Assess Pathways' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

OSTrails aims to advance processes and instruments for Planning, Tracking, and Assessing scientific knowledge production beyond state-of-the art, working with various national and thematic contexts, improving existing infrastructure, and connecting key components. For the Plan stage, OSTrails aims to increase the efficacy of Data Management Plans, turning them from static narratives to living, interconnected “machine actionable” resources, making them the instrument of choice for improving quality of RDM. For the Track stage, OSTrails is set to establish an open, interoperable and high-quality ecosystem of Scientific Knowledge Graphs, enriching them to become evidence of communities’ FAIR implementations. For the Assess stage, OSTrails aims to deliver modular and extendable FAIR tests, towards “machine actionable” metrics, complemented by user guidance embedded in tools assisting any stage of research life cycle.  Presented as the OSTrails Commons, the resulting methods, tools, services, guidance & training form the necessary building blocks to provide end-to-end solutions that serve: (i) researchers and research support personnel realise FAIR at any stage of the research life cycle, for any digital object; and (ii) research funding organisations, research performing organisations, publishers to drive the improvement of the quality of RDM for any shared, funded and published research product. OSTrails will lower the barriers to plan and practice FAIR research, moving the dial from FAIR assessment to FAIR assisting practice; also, to enhance traceability and improve evidence-based evaluation of research via a more networked scholarship. OSTrails is deeply rooted in the work of 38 partners, 22 research performing organisations, 5 ESFRI Clusters, and 24 pilots, acknowledgi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Round table for enhancing access and service to microsystems technologies.'.

assistant: **Objectives**

The planning is to make this first step in the collaboration within two years by the organisation of three two-days general meetings: kick off meeting, an intermediate meeting and a final meeting. Two more specific meetings will be organised for technical visits and, intermediate discussions on long-term potential collaborations. That corresponds to a total of four meetings at the four infrastructures deliverables for the MST/RT project are mainly two documents:- Year one: Procedures analysis and recommendations for improving the access of each infrastructure (deliverable1);- Year two: Collaboration perspectives in sharing technological resources and in (Tele)design.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Study of inflammation on a murine model of HCV' (HCV-PARP) under Sixth Framework.

assistant: **Objectives**

Hepatitis C virus (HCV) infection is a major human health problem due to its extremely high prevalence (estimated 200 million of chronically infected individuals worldwide) and severe complications of chronic hepatitis. Prior efforts to understand the pathogenesis of this medically important infection have been thwarted by a lack of useful animal models.The main part of my current work, supported by a Marie Curie fellowship, is to create a new model of chronic HCV which should combine the effects of the tumorigenic potential of the viral proteins with the effects of liver inflammation. The new transgenic model will be based on an inducible expression of the viral proteins, which, if successful, should give rise to the host immune response and liver inflammation. The expertise of my current laboratory is in oncogenesis and the regulation of apoptosis, whereas my host institution is specialised in the study of inflammation and a pharmacological approach to its control. We will combine these two areas of research in order to examine the link between inflammation and tumorigenesis in the context of HCV dependent HCC.Since the host institution has a strong tradition studying the molecular mechanisms mode of action and the physiological effects of poly-(ADP-ribose) polymerase (PARP) inhibitors in the context of inflammation, we will focus on the role of this nuclear enzyme on the aforementioned processes. The use of PARP inhibitors opens new perspectives in treatment of inflammatory disease with possible benefits for the outcome in terms of cancer development. The collaboration between the laboratories in Pecs and in Montpellier will assure that the transgenic model is exploited both with respect to inflammatory response and to cancer development.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'The World’s Most Secure Cryptocurrency Safeguarding Solution' (Ngrave).

assistant: **Innovation**

Blockchain technology is increasingly gaining traction. The total market cap of all cryptocurrencies combined stands at€177B and is considered to be still very early stage, with catalysts such as institutional or mass adoption having yet tooccur. Also, venture capital is increasingly entering the market, with a 280% investment growth in 2018 compared to 2017 .The industry is facing one enormous hurdle for mass adoption: insufficient security. Every single day, over €6M aremaliciously stolen from crypto wallets. In 2018 alone, theft accounts for a staggering €2.2M . Holding cryptocurrencypositions today is far from safe and crypto investments are continuously at risk. Existing safeguarding alternatives have beenproven to lack in security, revealing multiple weaknesses in their approach. The most crucial weakness is the onlineconnection that they require. Establishing such a connection exposes the crypto wallet to a large attack surface, luringmalicious hackers. This is where NGRAVE comes in. NGRAVE is the world’s first end-to-end and most secure solution tomanage and protect cryptocurrency investments. It consists of i) a “hardware wallet” (to the right), ii) a quasi-indestructible“cold storage” solution, and iii) a mobile application (catering for fetching data from and for doing the last-mile communicationwith the blockchain; there is no risk as the sensitive data never leaves the hardware device). NGRAVE offers a gamechanging disruptive crypto safeguarding solution that can function fully offline, meaning that it never exposes the secretcryptographic key(s) that the hackers are after. This offline aspect translates into a statistically non-existing attack surface asthere is no online exposure of the key, ever. European leaders have come to a consensus that the innovat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Living in a sustainable world focused on electrified rail' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

LivingRAIL will develop scenarios on the state of living style, cultures, mobility and economic activities in Europe by 2050 and explore a vision on the future role of the environmentally friendly, electrified railways within them.LivingRAIL will elaborate prospective and normative scenarios investigating possible evolutions leading to a reduction of the environmental harm of transport and in the same time to increase – or at least maintain – our quality of life. The scenarios will be detailed by trends in society, policy, economics, spatial planning, urban development, technology and transport sector operations to gain profound understanding of the sector interrelations. With the help of these detailed assessments the project will elaborate a “railmap” out of alternative pathways to approach the 2050 vision from today’s situation.Based on today’s best practice the analytical work will investigate how the railways and related transport modes can develop technically and in organisational and operational terms to achieve the 2050 targets and how spatial and urban planning, transport policy and other areas can contribute to achieve the 2050 targets.  A broad set of interviews and workshops using visioning and roadmapping techniques will be conducted.LivingRAIL will foster an intensive dialogue between politics, rail sector, spatial planning actors and civil society to develop jointly technology pathways and feasible organisational options to implement the vision 2050. The target groups: political decision makers, railways, rail supply industry, transportation providers, spatial planning authorities, transport associations, passengers’ organisations and academia will be involved in the dialogue process from the very start. Thus the LivingRAIL results will be checked in the