RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Optical dissection of cortical motor circuits' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The motor cortex plays a key role in learning and orchestrating fine voluntary movements, which dominate many aspects of our daily lives.Despite decades of research, considerable controversy remains over the functional organization of this forebrain area and its role in goal directed action. In this project we will combine cutting edge in vivo two-photon imaging, decoding methods and optogenetic manipulations to study different motor related circuits with single cell resolution. This approach will provide us, literally, unprecedented insights into the activity dynamics of large cortical networks during goal directed action. We expect that these experiments in rodents will not only help us understand some of the basic neuronal circuit mechanisms that govern our own actions, but they can potentially pave the way towards more targeted strategies for neuroprosthetic devices.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'High-Throughput Cryogenic Spectroscopy for Glycan Analysis'.

assistant: **Innovation**

Glycans, or oligosaccharides, are ubiquitous in biological systems. Because they decorate the surface of cells, they play a key role in virtually all cellular recognition processes and are implicated in almost every major disease.  Despite their importance, the characterization of glycan primary structure lags far behind that of proteins and DNA because of their intrinsic isomeric complexity. The isomeric nature of the monosaccharide building blocks, the stereochemistry of the glycosidic bond, the possibility of multiple attachment points, and the occurrence of isomeric branched structures all make glycans difficult to analyze.Although mass spectrometry (MS) is one of the most sensitive approaches for glycan analysis, it has difficulty to distinguish all these various types of isomerisms. Ion mobility spectrometry (IMS) combined with MS has demonstrated some ability to identify glycan anomers and regioisomers, but cannot easily distinguish isomeric disaccharides, for example.We have recently demonstrated that cryogenic infrared spectroscopy provides unique vibrational fingerprints of glycans that distinguishes all the various types of isomerism. When combined with simultaneous measurements of mass and ion mobility, these fingerprints can be tabulated in a database and used to identify a given glycan from a mixture. However, adding a spectroscopic dimension to ion mobility and mass measurements requires additional time, which hampers it use as an analytical tool. To use spectroscopic data for real-world glycan analysis, one must multiplex the measurement process and record the vibrational spectrum of many species simultaneously.This project involves designing and constructing an instrument that combines state-of-the-art ion mobility separation, cryogenic ion spectroscopy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'A revolutionary, cost effective, ultra-compact proton therapy system for cancer treatment' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

Cancer is a global problem with 14.1 million new cases occurring annually and an expected increase of 68% by 2030. Ensuring effective and safe treatment remains a significant challenge for healthcare organisations. Studies have shown proton therapy to be effective in treating many types of tumours, including tumours of the prostate, brain, head and neck, central nervous system, lung, and gastrointestinal system as well as cancers that cannot be removed completely by surgery. Proton therapy is the most advanced type of external-beam radiation therapy that uses protons at high energy to destroy cancer cells. Proton therapy can be used alone or combined with other treatments e.g. radiation therapy, surgery, chemotherapy, and/or immunotherapy. Proton therapy is routinely used for cancer treatment however it is limited by the sheer size and expense of the systems. There are currently only 66 operational proton therapy facilities in the world, addressing only 3-5% of clinical demand. HIL has developed an ultra-compact, high-performance system for Proton Therapy. HIL’s advanced particle accelerator and beamline technologies aim to make PT widely accessible by offering highly cost-effective single-room solutions. During the innovation project, HIL intends to scale-up the performance of the laser proton accelerator, customise the design of the delivery system, and clinically validate the laser proton performance. The project will also enable crucial commercial activities including implementation of IP strategy, communication strategy and scouting potential customers.


**Keywords:** Proton therapy, cancer treatment, nanotechnology, high intensity laser, spatial efficiancy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Multiple Organisation Interconnection for Collaborative Advanced Network Experiments' (MOICANE).

assistant: **Innovation**

The MOICANE project is focussed on the implementation and integration of a Virtual Laboratory" environment, where different actors (universities, research institutes, manufacturers and network carriers) can join their efforts and share their resources (theoretical studies, simulations, sophisticated devices, on-field experience) in carrying out network research activities. The MOICANE network pilot, where the "networked collaboratories" concept is going to be instantiated, will be based on several DiffServ islands (IETF's "Differentiated Services") throughout Europe, and will need to feature a heterogeneous network periphery, to allow the partners to enter the network through different access technologies: LAN, xDSL, wireless (IEEE 802.11d and DECT) and fiber optic solutions. A key point of the MOICANE activity is the experimentation of various network accesses and their functional and performance interoperability with a QoS capable IP backbone.Objectives:1) Networked collaboratories: MOICANE aims to create a virtual lab environment on an IP-QoS pilot, where research actors can share their knowledge, experience and devices to achieve a profitable synergy, in line with main RN objectives.2) Deployment of diverse access technologies (LAN, xDSL, fiber and wireless-DECT, IEEE 802.11d and satellite) whose integration, tested in a real environment, will allow to analyse the interaction among services, access and QoS-capable core network sections, in each island.3) Setup and interconnection of QoS-capable DiffServ islands, linked via high-speed wired connections, satellite links or legacy Internet, where QoS will be preserved across the domains and the access/core boundary. MOICANE addresses the WP 2000 thematic priorities on development/convergence of networking infrastructur
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'EU-CHINA Nuclear Education and Training Cooperation' under Seventh Framework.

assistant: **Concept**

The project aims to coordinate the cooperation between the EU and China in the field of Nuclear Education and Training. The project consists of 6 Work Packages. The first three Work Packages are establishing the strategy for long term cooperation in Education and Training and Knowledge Management in the areas of Nuclear Engineering, Radiation Protection and Waste Management and Disposal. The strategy will be developed on the basis of  the exchange of information on courses, curricula and training programmes and by evaluating the needs for academic education and professional training according to the future perspectives for nuclear technologies. The fourth Work Package addresses the implementation of mutual recognition of curricula between European and Chinese academia and the exchange of credits for students. The proposal includes the design and development of pilot courses in the three areas. The fifth Work Package addresses the identification, the technical description and the access modalities and conditions of infrastructures and laboratories accessible for the student and researcher exchange programme. The sixth Work Package covers the project management, the reporting and dissemination of the results and the knowledge management. The project resources cover 40 person-months provided by the European partners under the coordination of the European Nuclear Education Network Association. The European partners include the ENETRAP-II and the PETRUS-II Coordinators and their consortia, currently involved in the development and implementation of  European Fission Training schemes in respectively Radiation Protection and Waste Management and Disposal under the 7th Framework Programme. The mirror project financed by the Chinese Atomic Energy Authority runs in parallel with
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Remote wireless water meter reading solution based on the EN 13757 standard, providing high autonomy, interoperability and range' (WIMBex), addressing dissemination and exploitation.

assistant: **Impact**

Meter reading is the backbone of the home water billing system. If meters are read incorrectly or not read at all, it will cause a chain reaction of added events that add unnecessary expense and create customer dissatisfaction. Consortium SMEs have identified a clear need to develop a smart wireless water metering system based on the European Standard EN 13757 ""Communication systems for meters and remote reading of meters"".The system will be suitable for use in a variety of water metering scenarios, will require no maintenance and will provide authenticable and secure data transmission as well as timely and accurate recording of the consumption of water which will help in identifying any leakages through the analysis of the actual quantity supplied and recorded by the meters.The commercial objective is to develop a powerful set of new features to the SME wireless EN 13757 platforms, to enable the products and services of consortium SMEs to keep pace, and even surpass the future needs (high autonomy, interoperability and long radio range) of the emergent Automatic Water Meter Reading (AWMR) market in Europe. The project also aims to exploit aspects of the EN 13757 standard, which are not fully exploited as yet, and in this manner to add value to a European standard""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Social Science and Humanities in the European Research Area - Exploring the development of the research agenda'.

assistant: **Objectives**

Social sciences and humanities can make a relevant contribution to the construction of Europe by identifying possible answers to some of its main challenges : achieving enlargement, enhancing competitiveness with social cohesion, fostering sustainable development and quality of life, combining European with national identities, enhancing the role of Europe in international governance, reforming political institutions at European and national levels. In order to enhance the strategic monitoring of FP6, the European Commission - DG Research has created an Advisory Group on Social Sciences and Humanities and the European Research Area" (SSH-ERA). The Advisory Group on Social Scieces and Humanities should give advice to the European Commission and stimulate the European research community regarding the following objectives : a) Identifying the research priorities in the thematic priority 7 b) Enhancing the interface between SSH and the other thematic priorities c) Developing the interfaces between SSH and Community policies d) Anticipating new problems and scientific and technological needs e) Exploring a SSH approach on Research and Innovation f) Defining the strategy to build the European Research Area The present project is designed to support the implementation of FP6 in general and Priority 7 in particular by developing a series of initiatives to stimulate and focus the debate on the research agenda. "
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Middleware for memory and data-awareness in workflows' (MAESTRO) targeting Horizon 2020.

assistant: **Abstract**

Maestro will build a data-aware and memory-aware middleware framework that addresses ubiquitous problems of data movement in complex memory hierarchies and at many levels of the HPC software stack.Though HPC and HPDA applications pose a broad variety of efficiency challenges, it would be fair to say that the performance of both has become dominated by data movement through the memory and storage systems, as opposed to floating point computational capability. Despite this shift, current software technologies remain severely limited in their ability to optimise data movement. The Maestro project addresses what it sees as the two major impediments of modern HPC software:1. Moving data through memory was not always the bottleneck. The software stack that HPC relies upon was built through decades of a different situation – when the cost of performing floating point operations (FLOPS) was paramount. Several decades of technical evolution built a software stack and programming models highly fit for optimising floating point operations but lacking in basic data handling functionality. We characterise the set of technical issues at missing data-awareness. 2. Software rightfully insulates users from hardware details, especially as we move higher up the software stack. But HPC applications, programming environments and systems software cannot make key data movement decisions without some understanding of the hardware, especially the increasingly complex memory hierarchy. With the exception of runtimes, which treat memory in a domain-specific manner, software typically must make hardware-neutral decisions which can often leave performance on the table  . We characterise this issue as missing memory-awareness.Maestro proposes a middleware framework that enables memory- and data-awar
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'a Multimodal Authoring and Gaming Environment for Location-based coLlaborative AdveNtures' (MAGELLAN).

assistant: **Innovation**

Computer games represent a vast economic market, a key driver of technology, and an increasingly powerful medium for a broad range of applications. The latest wave of innovation for computer games is 'mobile' and, more precisely, 'location-based'. These outdoors mobile experiences are radically different from traditional computer games or their mobile equivalent. They focus the players' attention on the real world around them as much as on the digital world of the game, aiming to create a powerful juxtaposition of the two.Although location-based gaming is an industry on the verge of explosive growth, the creation and deployment of such experiences, especially those involving multiple participants, is simply out of reach for the vast majority of creative industries and authors because of the blend of many cutting-edge technologies they require, their hard to master limitations, and the complex gaming concepts they employ.The first objective of MAGELLAN is to deliver an unprecedented authoring environment based on visual authoring principles in order to enable non-programmers, as well as more advanced users, to cost-effectively author and publish multi-participant location-based experiences. The second objective is to deliver a scalable web platform featuring social networking means and supporting the publication, browsing and execution of a massive number of such experiences. Finally, MAGELLAN will produce a series of guides for authors of location-based experiences that will constitute a reference for interested people as well as a foundational document for future research in the field.To achieve this, MAGELLAN will adopt a holistic approach integrating interdisciplinary research involving a complementary group of world-class experts from multiple scientific and technol
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Hypermethylated DNA detection using NanoGaps' (HYMEDNA), addressing dissemination and exploitation.

assistant: **Impact**

HYMEDNA prepares commercialization of very sensitive point-of-care biosensors for early-stage cancer detection based on the electrical detection of hypermethylated DNA (hmDNA) inside nanogaps.Only recently the awareness has risen that local hypermethylation of DNA provides a generic marker for a wide range of cancers. A robust, simple and cheap method for detecting hmDNA at low concentrations in blood, urine or faeces would be a major step forward in the early-stage detection of cancer. Existing hmDNA detection relies on fluorescent read-out, which requires dedicated laboratory handling. Our technology is based on electrodes separated by a tunable nanogap. hmDNA is trapped and highly concentrated in between the electrodes using methyl binding domain (MBD) proteins. MBD binds specifically to methylated CpG sequences and thus provides the direct recognition of the targeted methylated moieties, contrasting existing DNA detection methods which commonly employ DNA (or PNA) oligos and rely on sequence specificity. After target binding, the conductivity of the trapped hmDNA is enhanced, for which we provide alternative routes. The detection step is formed by a simple measurement of the electrical conduction between the electrodes. As our detection scheme relies on completely turning on the conduction instead of only modulating it (as in other electrical detection schemes), an exceptionally high sensitivity is expected. As the most competitive advantages we identify (1) high selectivity (specific chemistry) and sensitivity (“on-off” effect), (2) simple, scalable device concept, (3) robustness against environment, (4) small size (allowing for implementation in a bioassay device for multiple target molecules), and (5) low cost price.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Extended service-life and improved properties of wood products through the use of functional nanoparticles in clear coating and adhesive systems' (WOODLIFE).

assistant: **Concept**

The long term objective of the WOODLIFE project is to provide coated and glued wood products with substantially improved durability for a more sustainable society. The project aims to develop new water-based clear coating systems for wood with improved UV-absorbing properties, and to develop new water-based thermoplastic wood adhesives with improved mechanical properties. The new coating and adhesive systems will be designed through molecular manufacturing of inorganic nanoparticles, nanoclays and composite organic-inorganic binders with predictable and controllable properties. Wood is an excellent building material with a high strength/density ratio and it is a renewable resource. For outdoor use it is, however, necessary to enhance the durability of wood materials due to the high sensitivity for UV degradation. Traditionally, organic UV-absorbers are used in clear coatings for wood, however these substances degrade upon outdoor weathering. New UV-absorbing systems for clear coats will be developed in the project based on nanoparticles of CeO2, ZnO and TiO2. With these new systems the service-life of the coated wood will be extended and the cost for maintenance and wood replacement will be decreased. If the mechanical properties of water-based thermoplastic wood adhesives such as PVAc can be improved it would be possible to use the wood products based on these systems for a longer time, leading to a more sustainable society. It would also be possible to use PVAc adhesives instead of the more expensive MUF/PRF adhesives in some load-bearing applications. Engineered nanoparticles will be developed in the project and will be introduced into wood adhesives in order to improve the properties of wood-adhesive joints. The nanoparticles and nanoclays that will be developed in