RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Generalised EMF Research using Novel Methods – an integrated approach: from research to risk assessment and support to risk management' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The EU population is increasingly exposed to new physical and chemical agents in the environment, some of which may be detrimental to public health. Of these, electromagnetic fields (EMF) are one of the most ubiquitous, with new EMF technologies and novel applications being actively developed and commercialised. To address pertinent questions on EMF and health, GERoNiMO proposes an integrated approach building upon existing European resources (epidemiological studies, exposure assessment techniques, mechanistic and animal models, expert networks), using, where appropriate, novel methods, to better understand potential mechanisms underlying possible health effects of EMF, to characterise population levels of exposure, and to further the state of knowledge on EMF and health.  GERoNiMO will focus on radiofrequency fields (RF) – as understanding of possible health effects is insufficient and a large proportion of the general population is exposed, with commercial applications continuing to grow – and intermediate frequencies (IF) – as applications are increasing and information on potential health effects  is sparse.  GERoNiMO will address all aspects of the call by meeting the following four main objectives: i) evaluate possible health effects (cognitive and behavioural development, cancer risk, and reproductive effects) of exposure to RF and IF in children and adults; ii) better understand mechanisms of biological effects (behavioural and reproductive effects, cancer, ageing, and Alzheimer’s disease) related to RF and IF; iii) collect better data on population exposure and improve health risk assessment for RF and IF; and iv) underpin policy development in Europe on RF and IF (including non-technological means of reducing exposure and best practices in risk communication
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Fire Retardant Line Hoses for Forestry Fire-Fighting Applications' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Fires destroy between 200K and 600K hectares of forest every year in the EU-15, accounting mainly for the Mediterranean countries (Greece, France, Italy, Portugal and Spain), and costing the European economy between 200 and 600 million Euro per year, and a number of live loss. Direct earth fire combat using hoses is a key method used for fighting fires in forestry environments, often used in conjunction with air fighting and other methods. Given the unpredictability of fire in natural environments, versatility and safety are key element to de successful action of the fire brigade. Currently used fire hoses cannot resist more than 1 minute to a direct fire of 350C, resulting in many cases in hoses burning as a consequence of now fire start ups. This has shown dramatic consequences in fire-fighter´s safety, as well as a decrease in the versatility and efficiency of direct fire combat action plans. The project aims to produce a novel fire-fighting hose system for forestry applications able to provide enhanced versatility, efficiency and safety of fire-fighters in their forestry protection action plans. The hose system will be made of a novel rubber formulation based on PVC/NBR using intumescent additives and fire-resistant components, particularly based on nano-clay inclusions. The hose will provide enhanced fire resistant properties, aiming at increasing current performance by 5 to10 times, while retaining similar mechanical specifications as currently exiting products in the market (weight, service pressure, curvature radius, min temperature, and resistance to abrasion, chemicals, hydrocarbons and ozone) The innovation is expected to impact in other applications for fire-resistant rubbers such as civil, industrial and military. From the scientific point of view, we expec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Delphi Mediation On-line System' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

The DEMOS (Delphi Mediation Online System) project will contribute to close the growing distance between European citizens and the decisions taken in Brussels and Strasbourg caused by the difference between regional, national and European interests. This aim will be sought with a new on-line integrated service supporting large-scale participation in all stages of the discussion process concerning European (and local/regional) political topics. The goal of the project is to develop and validate a new methodology to support democratic discussion and participation by developing a system, which allows online mediation and consensus forming with a high level of users. If successful the project will make a substantial breakthrough in on-line consultation where there currently exists no acceptable means to handle consensus and opinion extraction electronically.OBJECTIVESThere are four major objectives to be achieved by the DEMOS project:1. Development of a new participative methodology based on a sociological conflict resolution approach;2. An innovative and low-cost system architecture composed of novel software components of a Java platform;3. A running prototype installed and deployed at two trial sites and linked to selected reference sites to demonstrate the system's usability and validity;4. A strategy for dissemination and exploitation, including the founding of a new company to commercialise DEMOS.DESCRIPTION OF WORKThree well-proven methods of social research and organisation development will be combined: the Delphi polls, the Survey technique, and the Mediation technique. This methodology is the basis for the design of an appropriate system architecture and for the implementation of a powerful socio-computational system. The methodology and the system will be validat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Aloe vera - maximising yield of effective compounds and development of cosmetic products with standardised content of these compounds' under Sixth Framework.

assistant: **Concept**

Natural substances and plant extracts are increasingly important components in the cosmetic and pharmaceutical industry as well as in the wellness sector thanks to its inherent characteristics and their high acceptance among the consumers. Therefore, the market share of natural products has been growing very fast, and for instance plant based drugs represent today a market share of approx. 30 % of Pharmaceuticals. Aloe vera is benefiting of this demand on natural ingredients thanks to its unique healing an d nutritional characteristics: The Aloe vera leaf contains over 75 nutrients and 200 active compounds, including 20 minerals, 18 amino acids, and 12 vitamins and works effectively against sunburn and UV irradiation.However, up to now no objective method f or quality demonstration and assessment of Aloe Vera has been established, which affects the competitiveness of European producers since they can only compete against imported raw material through offering a higher quality product. The companies of the consortium consider that an European project is the best mean to perform the necessary study and development to establish the regulations and standards that will guaranty their permanence in market keeping to their current product quality.The AMAY project ai ms at obtaining:- Exchange of best practises for plantations (maximising yield) regarding soil quality, cultivation methods, plant cultivars- Isolation and Quantification of Aloverose by NMR (irregularly acetylated polymer of Mannose)- Development and testing of new products with standardised content of effective compound
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Characterizing the clinical relevance  and the mechanism underlying TRIB2-mediated drug resistance to MEK inhibitiors in the context of melanoma' under Horizon 2020.

assistant: **Concept**

Melanoma is the most aggressive form of skin cancer resistant to all standard therapies. Currently, the established treatment of metastatic melanoma includes dacarbazine (DTIC) administration associated with response rates of between 10-20% with severe side effects during treatment. Recently, the BRAF inhibitors (vemurafenib and dabrafenib) and the MEK inhibitor (trametinib) were approved for the treatment of melanoma patients with mutated BRAF (about 50% of patients) while there are several PI3K, AKT, mTOR and MEK inhibitors being tested in clinical trials. However, the effectiveness of all these treatment modalities is limited by intrinsic or acquired resistance. The host lab has discovered a novel mechanism of resistance to a broad spectrum of drugs in clinical trials/use for melanoma therapy mediated by the kinase-like protein TRIB2. This means that TRIB2 could be used as a biomarker to select melanoma patients for specific treatment options and to develop co-treatment strategies to overcome drug resistance. This project pretends to (1) understand the mechanisms underlying TRIB2-mediated resistance to MEK inhibitors and to (2) further develop TRIB2 as a prognostic and predictive biomarker for melanoma. Ultimately, the expected results will be highly relevant for the clinic as they might allow to select melanoma patients for specific treatment options and to develop co-treatment strategies to overcome TRIB2 mediate resistance.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Natural baseline quality in european aquifers: a basis for aquifer management' (BASELINE).

assistant: **Innovation**

Problems to be solvedThere is currently no standard to assess the natural baseline quality of groundwater.This is requireda) as a basis for defining pollution andb) because existing limits are breached by entirely natural processes. The present-day baseline inorganic and organic geochemistry will be investigated using selected reference aquifers as well as historical water quality trends in these aquifers. State-of-the-art chemical, isotopic and radiometric tracer techniques and geochemical modelling will be used to define timescales of the natural geochemical processes. The results will be used as a scientific basis for underpinning the emerging Water Framework Directive and for making recommendations for monitoring natural aquifer systems. This will be achieved by working closely with an advisory group drawn from regulatory bodies in the consortium. The results will be presented through scientific channels, for use by policy makers and legislators.Scientific objectives and approachThe objective of the BASELINE project is to establish criteria for defining natural water quality baselines and develop a standardised Europe-wide approach for use in the emerging Water Framework Directive. Such a standard, based on geochemical principles, is needed to be able to assess scientifically the natural variations in groundwater quality since these alone may breach existing health limits. These criteria are also needed as a reference to assess quantitatively whether anthropogenic pollution is taking place. The project will also focus on timescales influencing the natural processes and the rates at which these are occurring and appropriate dating tools (including radioisotopes and CFC's) will be used. The extent to which pristine waters are being depleted by contaminated waters movi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Theoretical Chemistry of Unbound Electrons', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

T-CUBE aims at the theoretical modeling of chemistry involving the continuum. Traditionally, chemistry has been concerned with electrons that remain bound to the nuclei during a reaction. However, in many settings that deal with X rays or plasma, electrons can enter and leave the system; they are unbound.Most theoretical approaches for unbound electrons are not applicable to extended systems in complex environments. As a consequence, pathways and product distributions of processes such as dissociative electron attachment and Coulomb explosion are poorly understood. This hinders progress in laboratory and technology: The electron is a simple and versatile catalyst, but corresponding applications arestill in an infant stadium.T-CUBE seeks to overcome these limitations. Often, unbound electrons can be described by resonances, electronic states with complex-valued energy. In recent years, I contributed to advancing this approach significantly. Small molecules in gas phase can now be described with an accuracy that allows for quantitative comparison to experiment.Here, I propose to investigate the chemistry of unbound electrons in larger molecules and condensed phase, for example, in solutions, polymeric networks, and biomolecules. Aspects that we will address include: energetics and character of resonances in different environments, resulting changes in chemical reactivity, and the interplay of nuclear motion and electron loss.To achieve these goals, quantum chemistry for electronic resonances needs to be advanced substantially. We will develop electronic-structure methods suitable for over a hundred of atoms, a quantum embedding scheme for describing different environments, and molecular dynamics simulations that take into account electron loss. In addition, we will advanc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Next Generation Blockchain-based Supply Chain Traceability & Transparency Platform'.

assistant: **Concept**

Tilkal is a blockchain-based supply chain traceability & transparency platform that provides a full digital representation of a supply chain, end-to-end and in real time. Tilkal enables businesses to be: in control of their supply chains, compliant with the existing and upcoming regulations & transparent to all the stakeholders about their usage. Tilkal is developing a backbone solution to ensure trust and traceability for Industry 4.0. It offers traceability & visibility over a supply chain both up- and downstream. It combines a secured and provable B2B data sharing network (based on blockchain to enable reciprocal responsibility across the supply chain), with algorithms for supply chain analysis and scoring in real time.  We have early traction in agrifood, textiles, cosmetics, minerals & aerospace. Companies use beta Tilkal solution to improve control, compliance, sourcing origin and get fraud detection capabilities as well as to increase transparency towards their customers.


**Keywords:** Big data,Compliance,Transparency,Traceability,Logistics,Food chain security,Machine learning,Regulation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Towards quantitative brain studies with the positron camera posicam hlz-r - camera performance characterization and partial volume effect correction'.

assistant: **Concept**

Research objectives and content The framework of the proposed project is the development of tools leading to improve quantitation on images obtained by positron emission tomography (PET) by an interdisciplinary cooperation between the Grupo de Bioingenieria y Telemedicina (Universidad Politecnica de Madrid) and the Centro PET Complutense. Particularly we will work on the implementation of a reconstruction image method that improves partial volume effect correction, allowing better quantitation of tracer distribution in human brain studies, which present special importance in neurological and oncologic studies. Since this PET camera (the first in Spain) has been recently installed, we must start this work with a fully characterization of its imaging capabilities. Training content (objective, benefit and expected impact) The main result of this work will be an image reconstruction algorithm with improved partial volume effect correction which will have in consideration non-ideal real situations. Since PET imaging plays a fundamental role in areas of nuclear medicine such as neurology, cardiology, oncology and brain research (e.g. activation during cognitive processes), this areas will benefit directly from the improvements in quantitative analysis of PET images. Moreover quantitation in nuclear medical imaging contribute to more accurate assessment in diagnosis and treatment. Links with industry / industrial relevance (22) This project is highly linked with the Centro PET Complutense, a private research institute. In addition, the Grupo de Bioingenierfa y Telemedicina (UPM) has a strong collaboration with ITISA Biomedicina, a Spanish company active in nuclear medicine equipment production and marketing, that could be interested in the results of this project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Multi facEteD ImplementAtion of a mixed sofTwarE/hardware-based zero-trust framework for the computing continuum' (MEDIATE).

assistant: **Innovation**

Technological advances in Information communication Technologies (ICT) as well as the digital transformation of complex systems have led to the development of novel networks, platforms and systems, which have, in turn, kick-started the realisation process for multi-faceted technological collaborations and data-driven workflows on a scale never seen before. Consequently, an integration process among the different layers of complex systems and services has been unfolding raising significant issues and challenges in its wake. Hence, the digital data and collaboration spaces are all predicated upon the realisation of what is known as the computing continuum, which is based on the integration of cloud, edge and Internet of Things (IoT). Nevertheless, this has given rise to significant security and privacy risks especially since it is about systems that involve a high number of entities and devices with different profiles, processing a vast amount of potentially sensitive infoMEDIATE’s vision is to produce a robust technology, which will address the security and privacy attributes of the computing continuum. For this, it will put forth a complex architecture that is based on the concept of zero-trust and will assume a federated learning approach in order to perform security-based scrutinisation at all continuum levels. i.e. IoT, edge and cloud, using security models that can be updated, redistributed and reconfigured across it. The actual features of the MEDIATE framework will support major topic outcomes such as cybersecurity resilience through reconfiguration, vulnerabilities mitigation through cyber threat analysis, secure integration at the IoT level through software and hardware-based security sensors and trust and security for massive ecosystems through the use of feder