RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'IN-CYTES A HIGH-DENSITY MICROELECTRODE ARRAY PLATFORM FOR LARGE-SCALE INTRACELLULAR FUNCTIONAL ASSAYS' to be submitted under Horizon 2020.

assistant: **Abstract**

MaxWell Biosystems AG (MxW) is a Swiss public limited company (AG) who developed electrophysiological platforms (hardware-software-bioassays) for basic research and drug testing on nerve cells. MxW’s aim is to develop In-Cytes, a radically innovative electrophysiology platform to assess neural connectivity for preclinical drug discovery for brain diseases. In contrast to the state-of-the-art technologies for quantifying neural connectivity, which either estimate indirect connectivity or feature poor spatial resolution, In-Cytes can measure physiological direct neural intracellular connectivity among thousands of neurons. This directly addresses the industrial need in pharmacy for neural connectivity bioassays, featuring high-throughput and minimum interference with neurons’ physiology for the development of effective drugs to cure neurodegenerative disorders, such as Alzheimer’s and Parkinson’s diseases.The proposed recruitment of an Innovation Associate will have significant impact on the business opportunities of MxW by bringing in lacking expertise for the development of In-Cytes. The envisaged grant will help to overcome the recruitment barriers of being a relatively unknown, small start-up enterprise that cannot compete with larger companies due to limited visibility, brand awareness, (perceived) career opportunities, salary and recruitment budget.The development of In-Cytes requires the employment of an academic expert with a multidisciplinary set of skills combining knowledge in neuroscience, microfabrication and data analysis. In turn, the innovation associate will have the opportunity to become an expert in the emerging field of bio-engineering. It is in the interest of the company to continue the employment after the initial year in order to develop the first
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'ANNUAL FIBRE REINFORCED POLYPROPYLENE COMPOSITES FOR INDUSTRIAL APPLICATIONS : DEVELOPMENT OF A QUALITY CONTROLLED FIBRE PRODUCTION CHAIN', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The project has three objectives, being :1. stimulation of the industrial use of annual fibre crops which can be grown in EU countries, especially indigenous crops like flax and hemp;2. development and optimisation of (pre)treatment and processing methods for annual fibres to specifically adapt them to function as reinforcers in composites with the synthetic thermoplastic polypropylene (PP);3. development of a composite material composed of polypropylene, isotropically reinforced by randomly oriented annual fibres (AFPP) and use of such material in industrial applications particularly automotive components.These objectives will be pursued by an integrated approach covering the complete production chain of AFPP, including fibre production, fibre opening, fibre treatment, matrix treatment, compounding process and production of actual prototype parts from composite materials. The most important issues for the purpose of the production of AFPP based parts with favourable properties, include : - optimisation of fibres' physical and chemical characteristics by the fibre opening ('pulping') process;- development of treatments to alter the composition of the individual fibres more radically by introduction of new components in/on the fibres; this project will develop two different treatments, the one making use of physically bonded hydrophobation agents and offering the possibility of relatively easy integration with the aforementioned opening process, the other being based on actual derivatisation by reaction with maleic anhydride (MA) and producing a more profound composition change as well as the possibility to obtain an addition chemical link with the matrix;- adaptation of the PP to increase its suitability as a matrix;- development of an efficient compounding process and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'From the Child's Genes to Parental Environment and Back to the Child: Gene-environment Correlations in Early Social Development'.

assistant: **Concept**

The role of children's behavior and temperament is increasingly acknowledged in family research. Gene-environment Correlation (rGE) processes may account for some child effects, as parents react to children s behavior which is in part genetically influenced (evocative rGE). In addition, passive rGE, in which parenting and children s behavior are correlated through overlapping genetic influences on family members behavior may account in part for the parenting-child behavior relationships. The proposed project will be the first one to directly address these issues with DNA information on family members and quality observational data on parent and child behaviors, following children through early development. Two separate longitudinal studies will investigate the paths from children s genes to their behavior, to the way parents react and modify their parenting towards the child, affecting child development: Study 1 will follow first-time parents from pregnancy through children s early childhood, decoupling parent effect and child effects. Study 2 will follow dizygotic twins and their parents through middle childhood, capitalizing on genetic differences between twins reared by the same parents. We will test the hypothesis that parents' characteristics, such as parenting style and parental attitudes, are associated with children's genetic tendencies. Both parenting and child behaviors will be monitored consecutively, to investigate the co-development of parents and children in an evocative rGE process. Child and parent candidate genes relevant to social behavior, notably those from the dompaminergic and serotonergic systems, will be linked to parents behaviors. Pilot results show children s genes predict parenting, and an important task for the study will be to identify medi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'multipurpose robotics for mAniPulation of defoRmable materIaLs in manufacturing processes'.

assistant: **Innovation**

APRIL project aims at implementing and deploying market oriented, low cost and multipurpose robots that supports semi-automatic tasks in manufacturing production lines that use flexible or deformable materials in industries of any size or domain. APRIL will use fine grasping, innovative computational vision technology, gathering of sensors information, as well the development of modular and different middleware layers and interfaces.  APRIL will provide innovative sensoring and computational vision supporting detection of slips, estimate weight, dynamic center of mass, or regulating grasping forces while manipulating deformable objects of different types (e.g. paper, chicken breast, shoes insoles, viscoelastic textile materials, cables, etc.). A federated approach, wireless communication, usage of multipurpose hands and placement of various sensors, will connect all robots to a cloud based knowledge base that will contain the needed information to perform the different jobs.APRIL system will be deployed in six different demonstration use cases across Europe. Robots integrated in the manufacturing processes will operate on several critical steps that affect production, packing and quality assurance on the different manufacturers involved as pilot sites. On one hand, introduction of APRIL system will produce an expected increase on safety and related health conditions of working environments. On the other hand, APRIL will enable an increase on productivity and quality of the final products; thus leading to a greater competitiveness of European industry.The project will be implemented in 40 months by 15 partners from 8 European countries.


**Keywords:** Automation, federated robots, flexible manufacturing, manipulation of flexible materials, robot hands
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Personalizing the Unconscious:  a Cognitive, Neural and Developmental Investigation' (IndUncon).

assistant: **Concept**

Consciousness is often described as the tip of the iceberg, under which a rich unconscious world exists. But is this metaphor accurate?The literature provides a mixture of contradicting findings, with some claiming that almost any cognitive function can be performed without awareness, while others arguing that unconscious processes are limited to routine, simple operations.Currently, there are two gaps in this body of knowledge, though; first, the field has almost solely examined group-level findings, without taking individual differences into account. Second, it is based on studies probing specific processes at specific time points; no study to date has tried to take a more global approach, looking for common mechanisms that persist over time, and potentially over tasks.Here, I aim at bridging over these two gaps, providing a novel framework: I suggest that individuals consistently differ in their Susceptibility to Unconscious Processing (SUP). I hypothesize that SUP is a stable trait that can explain conflicting findings and shed new light on the interplay between conscious and unconscious processes. Starting with a task for which evidence for stable individual differences exist, I suggest three possible neural mechanisms that can explain such differences. These mechanisms will be tested using electrophysiology, neuroimaging, and developmental studies. I also introduce a novel protocol for pitting conscious and unconscious processing against each other, and biasing this competition via feedback.Finally, I will conduct a large-scale study testing the riskier hypothesis that SUP might not only be stable over time, but also across tasks.Together, this study will provide a much needed, unparalleled systematic investigation of the reliability and replicability of key findi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Format software in an industrial design environment' to be submitted under Fourth Framework.

assistant: **Abstract**

Reduction of 5 to 15% of engineering costs due to reduced logic simulation.Where use of formal methods prevents a redesign, additional cost savings of up to 30% are expected.Increased value of CheckOff-M software tool product by 20%.This Demonstration Project will integrate a prototype tool using symbolic timing diagrams as a rigorous graphical specification language into an existing commercial tool (CheckOff). The improved tool will be evaluated through development of a PCI to Memory I/O ASIC. The new tool will allow designers to validate the correctness of an implementation against a design specification without the cost and time needed for traditional simulation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Yeast biodiversity as a source of innovations in food and health' in the context of a Seventh Framework call.

assistant: **Objectives**

Cornucopia will train a new generation of young scientists focusing on less studied yeasts with interesting traits, which could be applied in the food and health sectors. Yeasts are a divergent group of fungi that predominantly exist as unicellular organisms. The baker's yeast Saccharomyces cerevisiae is by far the best known because of its role in producing beverages, baking and recombinant drugs, such as insulin. S. cerevisiae is also the main model for the analysis of common features of all eukaryotic cells, and has been used in pioneering the development of several molecular biology, genomics and post-genomic tools. However, the yeast kingdom includes more than 1.500 other species that display a variety of unusual characteristics, and play an important role in their natural environments, but have so far been only poorly studied. These yeasts represent a large untapped potential to develop novel food and health related processes and products. We will make use of thousands strains available within Cornucopia to screen, using a variety of microbiological, analytical chemistry and bioinformatics techniques, for traits of interest to industry. such as ethanol-, acid- and osmo-tolerance, aromatic and off-flavor compounds and probiotic properties. Our young researchers will develop novel species-specific molecular, genetic and post-genomic tools to find out which genes determine the superior traits. They will “domesticate” new isolates so that they can be easily handled in the lab, and develop scale-up cultivations for applied purposes. We will benefit from yeast biodiversity and open new avenues within fundamental and applied research. Cornucopia, consists of seven leading yeast academic laboratories and three leading European industry partners, will provide a unique envi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Reading the mind’s eye at 7 Tesla  - A fMRI-based communication brain-computer interface for severely motor-impaired patients'.

assistant: **Concept**

The Advanced ERC project ColumnarCodeCracking has pioneered ultra-high field fMRI at 7 Tesla for sub-millimeter neuroscience applications targeting cortical columns and cortical layers. One sub-project of the ERC project was to explore whether it is possible to build new brain computer interfaces (BCIs) exploiting the strong signal quality and higher resolution achievable at ultra-high magnetic fields. As part of our research (Emmerling et al., 2017, http://cordis.europa.eu/news/rcn/124885_en.html) we discovered that it is possible to reconstruct letter shapes from activity in early visual areas that are merely imagined by participants during 7 Tesla fMRI scanning. Importantly, we could demonstrate that imagined letter shapes can be decoded from single imagination events of about 10 seconds without the need to average across multiple repetitions. These observations stimulated the idea for this PoC application, namely to use letter imagery for the first time as a communication BCI. We also have tested deep learning auto-encoder networks as part of the analysis and observed that these tools substantially increase the robustness of letter reconstruction. The three major goals of this PoC are 1) to perform 7 Tesla fMRI experiments with healthy participants to evaluate whether decoding brain activity patterns during letter imagery can be performed robust enough to be used as a communication BCI for severely motor-impaired (locked-in) patients,  2) to develop a BCI/neurofeedback software performing all required advanced online analyses, and 3) evaluate whether showing the online decoded letter during imagery helps participants to fine-tune the resulting shape. While 7 Tesla fMRI is not yet widely available in clinical settings, we aim to prepare first tests of the developed p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'BioREAD; a Continuous Barrier Quality Monitoring System for Organs-on-Chip'.

assistant: **Objectives**

Organs-on-chip are expected to play a crucial role in the pharmaceutical industry for drug development and study of organs and diseases. We propose the development of an electrical detector that enables simple, versatile and continuous quality monitoring of these devices and is essential for commercialization. Combined with recent advances in stem cell technology, Organ-on-Chips can be used to do drug screening on an individual level. Therefore it can serve as instrument for personalized medicine, by determining the effectiveness of selected compounds, as well as possible side-effects to determine safe drug doses on a person-specific level. Moreover, Organs-on-Chip will greatly contribute to a further reduction in the need for animal testing. Besides the pharmaceutical industry, Organs-on-Chip hold great promise for the food and cosmetics industry to test the safety of products.Organ-on-Chip systems need continuous monitoring of the quality of the cell barrier to guarantee reliable outcomes of the drug development tests. State-of-the-art methods, such as fluorescence and commercially available Trans-Endothelial Electrical Resistance (TEER) measurement apparatus are discontinuous, inaccurate and/or harmful for the cells and therefore unsuitable for pharmaceutical applications. Our innovation overcomes these disadvantages. It enables continuous quality monitoring of the barrier function of the organ, which is essential for the commercialization of Organs-on-Chip. The BIOS-Lab on Chip group holds an excellent record in high-quality TEER measurements, demonstrating direct current (DC) TEER-measurements in a gut-on-a-chip in a top-15 of most cited research papers in the journal Lab-on-Chip   in 2015 and has ample experience in the development of a blood-brain barrier on chip
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Cultural models of state liability: from the national systems to the community paradigm of federal state liability' in the context of a Sixth Framework call.

assistant: **Objectives**

1. The first objective is to demonstrate that the Community paradigm of State liability is different in form and substance from the national ones.1.1 To achieve this objective we will first compare the differences between national systems. Our research methodology will be based not only upon normativistic approaches on the governmental or legislative liability, but will widen the research field to the historic, sociological and political reality, inherent to the English, French and Spanish liability systems. The current normative structure, though relevant, will be taken as a starting point for a deep interdisciplinary analysis. Each model of liability reflects the legal culture and the politic myths of their society. This comparative law part will be studied in the first semester of the 1rst year.1.2 Moving from a macro-comparative level and/or an anthropological analysis of law, cultural and normative diversity within the European cultures gradually blurs. From inside, the province of legislative action has always been, and is still, out of the longa manus of law. The State liability for breach of Community law is new and different from the French responsabilite administrative and from the American or kelsenian constitutional control of law. This Community l aw part will be examined in the second part of the 1rst year.2. The second objective is to demonstrate that, though the Community paradigm is different from national ones, there is an interaction between these two areas. The candidate will show how in the last years the Community paradigm is having an impact not only on the legal, but the cultural lays of the State member mentalite. The cultural analysis of law does not have to lead to the protection of the national defence of the sfafus quo. A social and le gal c