RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Machine-learning polymer Gel's ELasticity and Structure' (MGELS) under Horizon Europe.

assistant: **Objectives**

Responsive soft materials, made of crosslinked polymer networks, have emerged as a promising class of systems. In particular, thermoresponsive hydrogels and microgels are widely used from drug delivery to cell engineering and art restoration. An important feature of such systems is their internal elasticity, which can be tuned according to their preparation protocol and crosslinker concentration. Despite recent progress in their modeling by means of numerical simulations, there is no way to know a priori their structure and elasticity from only their initial constituents, and hence, extensive exploration of initial parameters through simulations and experiments must be performed. To overcome this difficulty, in the present proposal MGELS -Machine-learning polymer Gel’s ELasticity and Structure- I will exploit my existing knowledge on Machine Learning (ML) methods to develop novel tools able to predict structural and elastic properties of hydrogels and microgel particles to design in silico polymer networks with desired features.The project is based on four objectives. The first is to develop a ML-Neural Network (ML-NN) able to predict the network structure using data from molecular dynamics simulations of microgels and hydrogels already collected from the supervisor. The second is to explore structural and elastic properties of new configurations of networks, following the methods established in the host group. As a third objective, we will create a new database of polymer networks that will be made open access at the end of the project. Finally, we will extend the ML-NN approach to predict elastic properties and to identify the onset of auxetic behavior. With the accomplishment of these goals, we will be able to fully predict polymer networks properties, being very app
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Controlling the Surface Chemistry of Intermetallic Compounds for Nanoscale Metal Interconnects' (CRIME).

assistant: **Concept**

Interconnects impose major limits on the performance on integrated circuits during the exponential reduction of feature size of microchips. The semiconductor industry faces challenges in the metallization of interconnects below the 10 nm half pitch and is looking to alternative metallization schemes to replace copper, the traditional choice for the last 20 years, which no longer meet the conductivity requirements at decreasing length scales. Binary metals such as nickel-aluminium (NiAl) have been identified as a promising candidate that performs well with respect to resistivity at critical dimensions (sub-10 nm) to replace copper. However, there are several challenges associated with the instability of these materials regarding surface oxidation, leading to performance degradation. The objective of CRIME is the in-situ removal of the surface oxide and in-situ passivation of binary intermetallic compounds to prevent surface oxidation at the sub-10 nm half pitch for interconnect applications. To meet the future size requirements of interconnects, the downscaling of the cleaning and passivation processes from blankets to sub-10 nm half-pitch and the formation of patterned lines, with the aim of sub-7 nm half-pitch, will be performed.This will be achieved through an interdisciplinary approach that combines material science, chemistry, chemical engineering, nanoelectronics, and physics, to test different metal oxide removal and surface cleaning chemistries in combination with organic and inorganic passivation layers in-situ to overcome the formation of an oxide top layer. The passivation layers will be deposited in the liquid and vapour phase and various analytic techniques will be used to elucidate the surface chemistry and surface reaction mechanisms.CRIME goes beyond the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Dissecting the crosstalk between metabolism and transcriptional regulation in pluripotent stem cells.' (MetEpiStem) under Horizon 2020.

assistant: **Objectives**

Pluripotent Stem cells (PSCs) can give rise to all differentiated cells of the body and the germ line, which makes them conceptually fascinating and a valuable tool for regenerative medicine. Mouse PSCs are devoid of any developmental restriction partly thanks to their “open” chromatin, characterised by remarkably low levels of repressive epigenetic modifications. Metabolism is a key feature that can be adjusted to meet the cell’s needs, and that has the potential to feedback on transcription and epigenetics. How metabolism is regulated in PSCs and whether this is important for their biology remains largely unknown.We recently found a new molecular mechanism by which energy production is coupled to pluripotency. Here we propose to deepen our understanding of how metabolism, epigenetics and transcription are reciprocally regulated for the self-renewal and differentiation of PSCs. To gain insights into how metabolism is dynamically regulated in concert with the transcriptome and epigenome, we will also use somatic cell reprogramming into PSCs, a process in which both the metabolic and epigenetic profiles must be reset to match those of PSCs. Moreover, taking advantage of the recent generation of novel human PSCs sharing most of the transcriptional and epigenetic features found in naïve mouse PSCs, we will explore how metabolic regulatory mechanisms key for the generation and maintenance of pluripotency are conserved throughout evolution. Altogether, large-scale transcriptional, epigenetic and metabolic profiling of PSCs, combined with cutting edge technologies for their generation, expansion and genetic manipulation, will give us the unprecedented opportunity to build a comprehensive computational model of the metabolic network in PSCs, and to study how gene transcription
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Cryopreservation of cattle oocytes at various stages during the maturation process' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

This program proposes to study the freezability of various maturation stage bovine oocytes in view to define a suitable protocol for oocyte freezing. The interest of freezing oocytes is to manufacture banks of frozen gametes to preserve the gene line of species threatened with extinction, or to aid in many areas of research in zootechnology. This research will be performed to evaluate oocyte potential sites of alterations : protein synthesis patterns, phosphorylation patterns, cytoskeleton organisation, intercellular coupling between oocyte and its surrounding cells after either rapid freezing or vitrification at different stages of maturation. The survival of frozen oocytes will be thus checked by their ability to complete maturation,to be fertilized and further develop to the blastocyst stage, but also by their competence to manifest synchronous protein synthesis pattern changes or synchronous cytoskeleton reorganization as unfrozen control oocytes. This will be a guarantee of inocuousness for such a freezing procedure.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Analysis of dendrochronological variability and associated natural climates in eurasia during the last 10,000 years' to be submitted under Fourth Framework.

assistant: **Abstract**

To reconstruct a range of climate variables in different regions of northern Eurasia to enhance our knowledge of natural climate variability on a range of timescales within the last 10,000 years and advance our understanding of the mechanisms and forcings that have generated this variability. This project is focused in the area of dendroclimatology. The absolute dating control and seasonal growth of  long tree-ring chronologies will be used to reconstruct a range of climate variables in different regions. The  project encompasses extensive development of new densitometric chronologies in northern Siberia, part of  ongoing work funded largely by The Swiss National Science Foundation.  In addition, the major collections of European historical and sub-fossil oak ring-width data, principally from  Great Britain, Sweden, Holland, Denmark, Germany and Poland, are being centralised, quality-controlled and  entered into a common European tree-ring data base . Some modern chronology development is being  undertaken to update these data and provide modern analogues for comparison with recent climate data.  The project will reconstruct changes in temperature and precipitation-related variables over a range of temporal  and spatial scales determined by the length, location and climate sensitivity of the available tree-ring data. This  work will generate detailed individual maps of summer temperatures over several centuries across northern  Siberia. These data will be interpreted in terms of large-scale atmospheric circulation patterns over western  Europe and northern Eurasia and within the context of the large-scale general circulation of the Northern  Hemisphere.  Tree-growth and derived climate variability will be compared with (less well resolved) independent evidence  of clima
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Marine and Maritime Research, Innovation, Technology Centre of Excellence'.

assistant: **Innovation**

With the economic recession behind it, the economy of Cyprus is expanding at a rate comparable to that of the global economy. Despite this welcoming trend, the investment landscape in research, technology development, and innovation (RTDI), a key factor in the economic competitiveness and sustainability of Cyprus — remains stagnant, with bottom-up initiatives towards a change remaining fragmented and underutilised. As a direct result, the innovation and entrepreneurial ecosystem of Cyprus remains at an embryonic stage, leaving Cyprus as a low-performing RTDI country within the European Union.Innovation activities in SSP cannot proceed without a solid scientific and research and technology development foundation. Despite Cyprus hosting three state universities (and a number of private ones) with a wealth of excellent research and scientific expertise, this significant resource remains untapped and rarely exploited beyond the confines of academia. To reverse this ultimately detrimental relation between research and innovation, Cyprus is in dire need of an intermediary to help the country rise out of its RTDI slumber. This proposal seeks the European Union’s support to establish in Cyprus a Centre of Excellence that fosters world-class research, technology development, and innovation activities. This will not be another academic entity but an institution developing practical solutions/products addressing the needs of the economy, and society, in Cyprus, the EU and the rest of the world in activities related to the marine and maritime sector.The proposed project, Marine and Maritime Research, Innovation, Technology Centre of Excellence (MARiTeC-X), seeks to play a key role in the country’s economic and social transformation through RTDI transformation, by setting up the Cyp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Short lead time patternless" production of prototypes and small batches of small to large castings"' (1994-1998).

assistant: **Concept**

The industrial objective is to meet the competitive needs and expectations of important engineering sectors which depend upon SME foundries supplying 'one-off' or small numbers of castings for the manufacture of original equipment or for the replacement of 'in-service' failures. Their principal requirements are for lower costs and especially reductions in lead time. The technical objective is to satisfy the industry needs by the development of a fast and versatile casting production process, having low operational and capital entry costs for use in SME foundries. It is proposed to eliminate the expensive and time-consuming intermediate stage of pattern and core-box production by the direct cutting of moulds and cores from pre-formed sand compacts using state-of-the-art CAD/CAM and CNC machining technologies. This concept has been assessed in a research feasibility study which identified the further work required. The major tasks include enhancement in CNC machines and post-processor software, developments in cutting tools and machining parameters and optimisation of sand compact processing including minimisation of resin binders and waste sand disposal. SME's specialising in these fields, together with SME foundries and casting users, will be partners in this project. Pre-competitive demonstration of the process in three SME foundries will be a major project task, and a significant contributor to dissemination and post-research commercial exploitation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Geometry-driven self-organisation in active living matter' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Living materials process information through their physical degrees of freedom, enabling autonomous functions beyond the capabilities of electronic systems. For example, a migrating cell uses its own shape dynamics to navigate through complex environments and decide which way to go. Yet, the principles underlying such physical information processing have not been identified due to the complexity inherent to problems involving fluctuating dynamic boundaries, and the need for a multidisciplinary approach to link theory with experiments.Building on recent scientific and methodological advances from my group, I propose to investigate how soft active materials perform computations and self-organise functional behaviours using the deformations of their own shape. Specifically, using surface anchoring effects in anisotropic materials as a paradigm for physical shape sensing, GOAL will identify how information is transferred from the covariant dynamics of active boundaries to surface-controlled bulk states, enabled by our novel approach to simulate active surface fluctuations (WP1-2). Combining theoretical results with experimental data from the technological frontier of biology, we will identify how the coupling between anisotropic materials and their geometry generates functional behaviours, such as autonomous object avoidance or embryo self-organisation (WP3). Lastly, we will leverage the visual accessibility of geometrical features to probe how machine learning approaches infer geometry-driven states and transitions from images, and to test our information theoretical predictions on shape sensing (WP4).GOAL will likely lead to the discovery of universal principles for shape-adaptive matter, because the nonlinear dependencies that arise from geometrical relations express fun
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Sr-isotope microsampling of feldspar phenocrysts: application to magma system analysis'.

assistant: **Objectives**

The aim of the project is to reconstruct magma chamber processes such as magma recharge and assimilation by using Sr-isotopes in-site analysis in zoned feldspar phenocrysts. The study will involve high-precision micro drilling combined with Thermal Ionization Mass Spectrometry. Chemical zoning patterns in the crystals to be investigated have been well documented using the electron microprobe during the PhD of the applicant. Using the micro-drill allows to control zone sampling width and shape, and thus the best possible spatial (and thus time-) resolution. Furthermore, the Sr isotopic compositions in crystals directly reflect the melt composition, whereas the chemical composition also depends on temperature, pressure, crystal chemistry , etc. This complementary information will be combined for the interpretation in terms of magmatic processes. The Parinacota volcano (north Chile) represents a long-lived calco-alkaline magmatic system. Sr isotope compositions of individual plagioclase zones in various samples should confirm the role of two mafic end-members suggested by the trace element study. In samples without evidence for recharge, it should show also the extent of assimilation. The Laacher See Volcano (Germany) is an inverted zoned phonolitic magma chamber. Sr isotope should help specifying more precisely the origin of the recognized different types of zoned sanidine phenocrysts and the assimilation processes. Possible cyclic basanitic magma recharge can also be tested.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Automated volcano monitoring system' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

To develop and build a rugged Automated Volcano Monitoring System that can be used in logistically difficult terrain without public facilities of power or telecommunication. Information to be gathered consist of a large number of parameters from widely separated sensors. Acquisition and interpretation of data in real-time is a paramount necessity in order to efficiently monitor high risk volcanoes and provide society with advance warning in times of volcanic unrest.The research team will build an user friendly real-time data processing system that will compare different  parameters and perform mathematical modelling. The development work will include:  1. A real-time display of the multiparameter data in a familiar computer environment will be made.  2. Automated transfer of the processed data to multiple recipients by international computer networks.  3. A network of cost-effective single frequency GPS receivers for the monitoring of ground deformation.  4. Integration of already existing sensors and a low power seismic array.  The system design can be applied either as a permanently installed long term monitoring system or, by using  portable components, as a mobile early warning system. A European target volcano will be selected for  installation and testing. The project will aim at transparency of different modules to ensure that individual parts  can be applied at different volcanoes with minimal effort and cost. The system can be easily adapted to other  environmental monitoring tasks.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Slope instability and submarine man-made structures - impact consequence evaluation' (1994-1998) under Fourth Framework.

assistant: **Objectives**

Research objectives and content - to quantify, understand and model slope instability in the Alboran Sea, the Cadiz Gulf and the Agadir region. - to evaluate the consequences of the impact of a mass-wasting flow against submarine structures The project is divided into three sections: research, collection and synthesis. The research deals with the geological survey of the study areas. On the one hand this involves obtaining a deep understanding and knowledge of everything referring to sea-floor topography, especially the slope, continental rise and basin provinces (batymetry and failure sediment bodies). This is acquired with advanced geophysical equipment. On the other hand it involves performing all the sedimentological and geotechnical laboratory analyses and tests. The collection of oceanographical data of the specific study areas permits us to evaluate the route of the mass-wasting flows. The gathering of technical information about submarine structures (type, the material they are made of, known damage and preventive measures taken to avoid geological process attack) are essential in order to assess the consequences of the impact The data is synthesized to create a standard model of the geological risk due to the coexistion of submarine structures and instability areas Training content (objective, benefit and expected impact) To achieve a high competence in geotechnic and sedimentology fields To create a standard model of the relationship between submarine structures and instability processes To promote the utilization of a very advanced instrument (Multi-Sensor Core Logger) Links with industry/industrial relevance (22) I will consult telephone and oil companies to collect technical information about submarine structures. A Spanich telephone company has expresses i