RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'IMPROvED: IMproved Pregnancy Outcomes by Early Detection; personalized medicine for pregnant women: novel metabolomic and proteomic biomarkers to detect pre-eclampsia and improve outcome' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

1 in 20 first time pregnancies are complicated by pre-eclampsia, the leading cause of maternal death in Europe. No clinically useful screening test exists; consequently, clinicians are unable to offer targeted surveillance or known/emerging preventative strategies. Consortium members have pioneered a personalised medicine approach to identifying blood-borne biomarkers through recent technological advancements, especially in the field of mass spectrometry and the comprehensive mapping of the blood metabolome and proteome.The overall objective of the IMPROvED project is to develop a sensitive, specific, high-throughput and economically viable early pregnancy screening test for pre-eclampsia. This will involve a multicentre, phase IIa clinical study to assess and refine novel and innovative prototype tests based on emerging metabolomic and proteomic technologies developed by SMEs within the consortium. The study will i) recruit 5000 first time pregnant women; ii) establish a high calibre biobank, augmented by accurate clinical metadata; iii) determine whether prototype predictive assays and algorithms translate to the clinical environment; iv) assess potential synergy of a combined metabolomic and proteomic approach and v) progress regulatory approval and development of the selected test into the clinical arena.The application of new technologies to identify ‘at risk’ patients in early pregnancy will allow stratified care with personalized fetal and maternal surveillance, early diagnosis and timely intervention.  If an effective test halved antenatal visits and administration of therapies (such as aspirin) to those at risk reduced the incidence of disease by only 20%, potential savings would approximate to €4 billion of the estimated €9 billion/yr spent in Europe providing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'REScoop Plus' (2014-2020).

assistant: **Concept**

REScoop Plus built on the knowledge and network of the REScoop 20-20-20 project. An interesting additional observation made in the project was that members of supplying REScoops change their behaviour reducing final energy consumption and investing money to produce RESenergy. The aim of the REScoop PLUS is therefore to get a better understanding and foster this behavioural change. It will identify and measure the best practices, share their knowledge, improve their activities in in their citizen’s engagement and energy efficiency actions and disseminate them to other supplying REScoops in Europe.   The objective of REScoop PLUS is to make REScoops in Europe go beyond their activities of producing and supplying energy and take up energy savings for their members as a new pillar in their organisation. The largest supplying energy REScoops in Europe have recently taken up this task in several experimental projects, with different rates of success for different measures and geographies. The aim is now to go beyond the experimental phase and create a toolkit with a range of best practice products like communication tools, ICT tools for better measurements or new business models that support energy savings of consumers/members by changing the behaviour of consumers that are ready for market uptake by REScoops to implement into their organisation in order to reduce the CO2 footprint of their members.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Mathematical study of Boundary Layers in Oceanic Motions' under Horizon 2020.

assistant: **Concept**

Boundary layer theory is a large component of fluid dynamics. It is ubiquitous in Oceanography, where boundary layer currents, such as the Gulf Stream, play an important role in the global circulation. Comprehending the underlying mechanisms in the formation of boundary layers is therefore crucial for applications. However, the  treatment of boundary layers in ocean dynamics  remains poorly understood at a theoretical level, due to the variety and complexity of the forces at stake. The goal of this project is to develop several  tools to bridge the gap between the mathematical state of the art and the physical reality of oceanic motion. There are four points on which we will mainly focus: degeneracy issues, including the treatment Stewartson boundary layers near the equator; rough boundaries (meaning boundaries with small amplitude and high frequency variations); the inclusion of the advection term in the construction of stationary boundary layers; and the linear and nonlinear stability of the boundary layers. We will address separately  Ekman layers and western boundary layers, since they are ruled by equations whose mathematical behaviour is very different. This project will allow us to have a better understanding of small scale phenomena in fluid mechanics, and in particular of the inviscid limit of incompressible fluids. The team will be composed of the PI, two PhD students and three two-year postdocs over the whole period. We will also rely on the historical expertise of the host institution on fluid mechanics and asymptotic methods.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Analytical approaches for the assessment of human exposure to polyhalogenated alkanes (PXAs)', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Chlorinated paraffins (CPs) are polychlorinated linear chain alkanes with high production volumes used as flame retardants and plasticizers in a wide array of consumer goods. CPs may be released from treated goods and have become widely distributed in the environment and human tissues. Humans are exposed to CPs via contaminated indoor dust and food, while certain CPs have been registered as United Nations Persistent Organic Pollutants (POPs) and their usage restricted due to well documented toxic and bioaccumulative properties. Recent evidence has suggested that banned CPs may have been replaced by compounds known as polyhalogenated alkanes (PXAs), which share very similar chemical structures to CPs, differing only by the addition of bromine atoms. Both CPs and PXAs comprise of mixtures of thousands of isomers, making analysis and quantification highly complicated. A recent pilot study of PXAs in indoor dust revealed that the replacement compounds may be present at similar levels as banned CP groups. Based on the physicochemical similarities, PXAs are predicted to share similar bioaccumulative and toxic properties as banned CPs, but have not been studied widely. This research projects aims to develop the first analytical procedures for quantification of PXAs in indoor dust and generate methods for assessing the occurance of PXAs in a variety of environmental matrices. Measurements in indoor dust samples from Europe and the United States of America will be used to conduct a world-first human exposure assessment for PXAs. Developed methods will then be applied for retrospective screening of PXAs in archived data files to provide a broad snapshot of PXA contamination in food and the environment for the first time. The outcomes of this project are intended to characterize t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Advanced Technologies for Laser Applications in Space' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The main goal of this ERA Chair project proposal is to develop new capacities in the field of Space-borne Laser Research and Applications in the region of Central and Eastern Europe, namely at the Institute of Physics of the Czech Academy of Sciences (FZU) - HiLASE Centre, Czech Republic, by establishing an excellent international scientist, Professor of Space Systems Engineering Massimiliano Vasile, as an ERA Chair and a leader of new research programme on Advanced Technologies for Laser Applications in Space. The new research group will focus on areas of laser use for space sustainability. The new research group will focus on areas of laser use for space sustainability. By preparing specific research and applications strategy, roadmaps, feasibility studies and project proposals in the above-mentioned application area, the ATLAS project will cut across all the aspects of the ERA Chair in transferring knowledge. At the same time, the project will help to popularize Space-born Laser Research and Applications to broad public.As the chosen research area cuts across two complex fields, laser science and space engineering, the Czech Republic’s scientific heritage in laser science, concentrated mainly at the HiLASE Centre, presents an unique opportunity for the development of laser space applications. The research at HiLASE focuses on the next generation of high-power diode pumped solid state lasers. HiLASE laser systems bring a unique combination of high pulse energy, high repetition rate and high efficiency; they are significantly more powerful, more compact, more stable, and more easily maintained than those driven by old-fashioned flash lamp technology. It all makes HiLASE the perfect engine for pushing even more the frontier of laser technology beyond its current limits
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Rapid intelligent sensing and control of forest fires' (1998-2002).

assistant: **Innovation**

The RISCOFF project will integrate intelligent acoustic and chemical sensors, wireless communications, GIS systems and command and control software in order to set-up and test a wide area fire alarm system which has a high potential to deliver a very rapid response time, leading to significantly reduced forest fire damage, and a low cost (per hectare) system which should be very attractive to forest preservation authorities throughout Europe and the world. The system will require EU wide RTD activities to refine acoustic and chemical sensor technology applying state of the art neural net based methods, GIS integrations and wireless communications. The project will impact environmental protection, safety, quality of life and employed in the forestry sector. The exploratory award will assist both proposal expansion and key aspects of technical and commercial feasibility.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Integrable gauge theories at finite temperature' (IGTaFT).

assistant: **Concept**

We propose a project to  explore the properties of supersymmetric gauge theories at finite temperature, with special emphasis on those that are integrable in the large N limit. In particular we study the de-confinement of these theories using the newest integrability methods which have recently proved to be a powerful tool in finding the Hagedorn temperature  as a function of the theory's coupling.  Progress in this field can lead to better understanding of the long unsolved problem of confinement in gauge theories and the de-confinement of confining theories such as QCD at finite temperature.  The project will also  investigate string theories on curved space with background fields.  The results of the Hagedorn temperature at strong coupling provide sharp predictions for how the  string theory duals should behave, but showing it directly has so far proved elusive.  The project will use the results for the Hagedorn temperature and its higher order effects to  as a guide-post to determine the correct world-sheet structure for both type IIB and IIA string theories on AdS spaces.  Uppsala University has been a world leader in developing techniques for exploring supersymmetric gauge theories, including integrability and localization, which have led to powerful results.   The project would fund a total of five post-doc positions and two graduate students over the five year period to investigate these questions, providing excellent scientific opportunities for young theoretical physicists.


**Keywords:** Quantum field theory, string theory, integrability
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Information Technology and Institutions Supporting Human Capital Accumulation and Exchange'.

assistant: **Objectives**

Information technology revolutions transform the production and exchange of ideas and drive profound institutional and cultural change. History provides unique settings to document the causal impact of changes in information technology and institutions, and the best evidence on their long-run effects.The objective of the research is to document the impact of revolutionary transformations in information technology and institutions using evidence from the European Renaissance. Printing was the new information technology of the Renaissance and is arguably the best parallel to the internet. Print media transmitted ideas that led to significant institutional change. But no quantitative research systematically documents the impact of these innovations.The research will innovate by constructing ground-breaking micro-data on media markets, human capital, and institutions; developing cutting edge estimators for high-dimensional data to measure ideas in the media; and using historical sources of exogenous variation to identify cause and effect.The research has three strands. The first will document the impact of competition on idea diffusion and institutional change during the Protestant Reformation. The research will construct firm-level data on all known books in German-speaking Europe 1450-1600, use high-dimensional estimators to measure ideas in print, and identify exogenous variation in competition from archival data.The second strand will document the origins of persistent differences in human capital accumulation by constructing new data on city laws that set up the first experiments in public education and on virtually all German university students 1400-1550, and by using local shocks to support causal inference.The third strand will document the impact of organizations
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Quantum Synthetic Models for Entangled Matter Out of Equilibrium' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

The exceptional features of many-body quantum systems out of equilibrium are intimately connected with the intrinsic limitations we face when simulating their dynamics on a classical computer, as both are a consequence of the fact that quantum matter is entangled. Digital quantum simulators, or quantum computers, promise to overcome these limitations. However, in the current era of Noisy-Intermediate-Scale-Quantum (NISQ) devices, large-scale fault-tolerant quantum computation is out of reach, making full-fledged quantum simulation an ambitious long-term goal. Still, NISQ devices already provide new horizons and opportunities for fundamental research in many-body physics. Indeed, in  their native hardware, they can be conceptualized as qubit systems evolving by discrete gates, measurements, and feedback, giving rise to completely new collective behavior and universal phenomena. This project has the ambitious goal of finding and theoretically characterizing new phases of matter which are exclusive to NISQ platforms, charting their largely unexplored phenomenology and possibilities. Taking on a fundamental perspective, at the intersection of many-body physics and quantum information theory, we will pursue this goal based on the study of synthetic models of quantum circuits and quantum cellular automata (QCA). The target results of this project include: (i) Prediction of new dynamical phases arising thanks to the building blocks of NISQ technology and identification of protocols to observe them in existing platforms; (ii) Deeper understanding of topical but hard problems in many-body physics out of equilibrium, made possible by the simplifying minimal structure of quantum-circuit and QCA models. The proposed research is expected to stimulate new synergies between different
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'European geothermal project to utilise hot dry rock/hot fractured rock resources: first phase of the construction of the scientific pilot plant. (HOT DRY ROCK ENERGY)' (1998-2002).

assistant: **Concept**

Objectives and problems to be solved :The Hot Dry Rock (HDR) / Hot Fractured Rock (HFR) concept aims to utilize the vast amount of heat stored in the Earth's crust but which is not accessible by conventional geothermal technology. In HDR/HFR systems, a well is drilled into high-temperature (typically >180 oC) fractured basement rock that underlies most of Europe and stimulated to enhance the natural permeability of the fracture network to create a reservoir or heat exchanger into which additional wells are drilled. Water circulated through the fracture network in the hot rock via the wells gathers heat, which can be extracted at the surface to generate electricity or for direct use. A recent 4-month circulation test between two wells at the Soultz site has demonstrated a substantial increase in the transmissivity of fluid between wells after hydraulic stimulation without any water losses or adverse environmental impact. Tracer and hydraulic tests suggest the existence of a subsurface heat exchanger with dimensions of hundreds of meters at a depth of 2900 to 3500 m. The most recent activity was a successful drilling campaign to deepen one well to 5000 m into igneous rock with a temperature of over 200 oC and a stimulation test that created a new reservoir at this depth. This 3-year stage of European HDR/HFR research programme at Soultz is the first phase in the construction and testing of the Scientific Pilot Plant.Description of work:The first phase in the construction of the pilot plant centres on design and installation of a three-well module that comprises one injector and two production wells, and on the creation of the reservoir and heat exchanger by stimulating the three wells. Each stimulation creates one of three parts of the reservoir/heat exchanger. Work packa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Targeting endothelial barriers to combat disease', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Tissue homeostasis requires coordinated barrier function in blood and lymphatic vessels. Opening of junctions between endothelial cells (ECs) lining blood vessels leads to tissue fluid accumulation that is drained by lymphatic vessels. A pathological increase in blood vessel permeability or lack or malfunction of lymphatic vessels leads to edema and associated defects in macromolecule and immune cell clearance. Unbalanced barrier function between blood and lymphatic vessels contributes to neurodegeneration, chronic inflammation, and cardiovascular disease. In this proposal, we seek to gain mechanistic understanding into coordination of barrier function between blood and lymphatic vessels, how this process is altered in disease models and how it can be manipulated for therapeutic purposes. We will focus on two critical barriers with diametrically opposing functions, the blood-brain barrier (BBB) and the lymphatic capillary barrier (LCB). ECs of the BBB form very tight junctions that restrict paracellular access to the brain. In contrast, open junctions of the LCB ensure uptake of extravasated fluid, macromolecules and immune cells, as well as lipid in the gut. We have identified novel effectors of BBB and LCB junctions and will determine their role in adult homeostasis and in disease models. Mouse genetic gain and loss of function approaches in combination with histological, ultrastructural, functional and molecular analysis will determine mechanisms underlying formation of tissue specific EC barriers. Deliverables include in vivo validated targets that could be used for i) opening the BBB on demand for drug delivery into the brain, and ii) to lower plasma lipid uptake via interfering with the LCB, with implications for prevention of obesity, cardiovascular disease and i