RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Synthesizing and Investigating the Exotic Electronic Properties of Two-Dimensional Metal-Organic Frameworks' (EMOF).

assistant: **Concept**

Metal-organic frameworks (MOFs) are coordination polymers synthesized by bonding organic ligands with metals or metal clusters. Recently, exotic electronic properties have been predicted theoretically for two-dimensional (2D) MOFs, such as topological non-trivial band structure (2D organic topological insulators and so on), superconductivity, half-metallic ferromagnetism and quantum spin liquid. 2D MOFs have been synthesized on metal surfaces by following the concepts of supramolecular coordination chemistry. However, molecular adsorbates on metal surfaces interact strongly with the underlying metal substrate. Therefore, their electronic properties are drastically modified.This project will focus on synthesizing and investigating the intrinsic exotic electronic properties of 2D MOFs on insulating, weakly interacting, and tunable gated substrates by ultra-high vacuum low-temperature Scanning Tunneling Microscopy and Spectroscopy with non-contact Atomic Force Microscopy. In order to achieve these ambitious targets, I have divided this proposal into three work packages: 1. synthesizing 2D MOFs on inert surfaces; 2. structural and electronic characterization of 2D MOFs; 3. tuning the exotic electronic properties of 2D MOFs on gated graphene devices. The applicant and the host group have initial results on the topics discussed in this proposal and are thus in a unique position to make ground-breaking contributions in this area.Understanding and tuning the growth and the electronic properties of MOFs will offer a versatile platform to realize topological electronics as well as different kinds of novel phenomenon in condensed matter physics. The bottom-up synthesis techniques guarantee a technological route which can easily be scaled-up to be used for applications. Longer term
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Kant in South America' to be submitted under Horizon 2020.

assistant: **Abstract**

A consortium of 4 EU Universities and 4 Southern American (SA) academic institutions analyze critically the development of Kant scholarship in Southern America in the last 15 years, following the booming of Kant studies in that continent over that period and the exponential increase of its quality. Top SA Kant scholars are enrolled in the project that promises to enlarge greatly the competence of EU colleagues and in turn profit from their feedback. Early stage researchers from both ends also take part to the exchange. The consortium builds on a web of established relations of most of the participants, at the personal and institutional level.


**Keywords:** Epistemology, Ethics, Political Philosophy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Seeing Citrulline: A Molecular Toolbox for Peptidyl Arginine Deiminases'.

assistant: **Objectives**

Roughly 1% of the world’s population is affected by rheumatoid arthritis (RA); a devastating autoimmune disease causing cartilage destruction and bone erosion. Recent evidences suggest that dysregulation of Peptidyl Arginine Deiminase (PAD) levels are associated with the onset of the disease, leading to the production of antibodies targeting the citrullinated neoepitopes. The exact role of each of the PAD isotypes in these pathological processes is unknown and fundamental questions on the intracellular activation mechanism and substrate specificity remain unanswered. Moreover, isoform specific and high affinity enzyme inhibitors are lacking thereby not only hampering fundamental research towards each PAD isotype, but also excluding PAD as a potential therapeutic target for these diseases.This proposal is aimed at developing innovative chemical biology- and molecular tools to study PAD functioning and protein citrullination in health and disease. The work reflects my interdisciplinary experiences as well as my interest I have obtained over the last years in chemical immunology as well as my ambition to improve patients wellbeing. More detailed, I aim to 1) find unknown PAD modulators, 2) find PAD substrates, 3) find selective and high affinity PAD inhibitors using enzyme-templated inhibitor evolution as novel lead discovery strategy, 4) explore multifunctional targeted PAD ‘nanosponges’ as advanced avidity-based nanomedicine approach and 5) explore unprecedented citrulline ‘eraser’ enzymes by innovative chemical biology strategies. The workpackages described in this ambitious and highly interdisciplinary proposal deliver high-end molecules and methods that can be used to answer fundamental (conflicting) questions on citrullination and PAD biology. Moreover, possible mole
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Revealing the architecture of replicated human chromosomes by sister-chromatid-sensitive fluorescence in situ hybridisation' (MicroChrom).

assistant: **Innovation**

The extremely long DNA molecules encoding complex genomes of higher eukaryotes must be organised inside the tiny volume of cells so that the genetic information can be read, maintained, and propagated across cell generations. Genomic DNA is folded into loops such that contacts between distant DNA elements can mediate transcriptional regulation or assembly of mechanically stiff mitotic chromosomes. Following DNA replication, each chromosome contains two DNA molecules, which interact with each other to support homology-directed repair during interphase and DNA compaction during mitosis.Advances in sequencing technology and super-resolution microscopy have revealed the 3D structure of chromosomes with unprecedented resolution, but conventional methods cannot distinguish between the identical sequence present in replicated sister-chromatids. The Gerlich lab has recently developed a new sequencing-based technique termed sister-chromatid-sensitive (scs)Hi-C, which allows the discrimination of intra- from inter-molecular contacts in replicated chromosomes. However, scsHi-C can only inform on interaction probabilities and does not reveal the actual 3D structure in single cells.Therefore, the aim of my proposed project is to establish a sister-chromatid-sensitive fluorescence in situ hybridisation (scsFISH) method for the highly multiplexed and automated detection of the 3D architecture of replicated genomes within individual cells. The ring-shaped cohesin complex is a key regulator of chromosome structure by forming loops within DNA molecules and by linking sister-chromatids. By depleting cohesin core subunits/regulators, I will use scsFISH to understand how cohesin structures replicated chromosomes. I will further investigate how sister-chromatid conformation influences the ef
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The production and collimation of jets from young star systems' to be submitted under Fourth Framework.

assistant: **Abstract**

Research objectives and content To investigate the magneto-hydrodynamic jets and outflows from young stellar discs by computer simulation with an up-to-date MHD code, addressing in particular the following questions 1. Whether the colied magnetic field configuration established by differential rotation and flux freezing forms a jet which is (a) steady over many rotation times of the disc, and (b) stable against perturbations in the ambient medium and the disc. 2. What range of morphology can be produced by varying the initial conditions and parameters of the model. 3. How the disc composition and dynamics are affected by the jet-with particular reference to theories of the early evolution of planetary systems. 4. How jets and slow bipolar molecular outflows are related (e.g. whether the latter are also produced or driven by MHD processes in the circumstellar disc). Training content (objective, benefit and expected impact) Study for the Ph.D. degree, providing specific qualification for professional research in computational astrophysics and astronomy, The skills involved are also applicable in a wide range of academic and industrial fields, wherever high-level numerical or simulation techniques are required. In addition to research, the training will involve some taught courses and tutorial work.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Versatile Hydrogen Transfer for Transport Applications' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

While the battery-electric technology could serve as a viable option for passengers’ cars and light-duty vehicles, hydrogen, especially in its liquid form (LH2), offers a promising avenue for decarbonizing larger-scale transportation. To answer the projected 10 billion annual passengers of aviation industry, LH2 is poised to play a key role in decarbonizing short and medium-haul flights.However, the current substantial energy and capex investment required for electrolysis, compression, storage, transportation and distribution is a costly energy vector and hampering LH2 replacement of diesel/kerosene 3 times cheaper.VHyTTA seeks to address the obstacles in hydrogen distribution by developing and demonstrating at TRL7 two multipurpose and flexible concepts of HRS: one fixed and one mobile to meet the needs of aviation, maritime and railroad transport sectors and distribute hydrogen to a wide range of vehicles including aircraft, ships (LH2 and GH2), trains, airport fleet, captive fleet and buses.VHyTTA main objectives are: -Develop, build and operate a new concept of fixed cGH2 station-Develop a novel, mobile refuelling solution capable of delivering liquid hydrogen fuel to aircraft & ships in line with customers’ requirements-Develop and validate models to digitalise the refuelling stations-Ensure top HSSE standards of HRS delivering hydrogen for multiple applications-Optimise logistics and value chain integration of a hydrogen hub at airports-Assess economics and environmental impact of the technologies and demonstratorsVHYTTA will contribute to reach strategical objective 4GW H2 production and distribution by 2030 with >100 refuelling station of hydrogen. Our forecast estimates 1504 routes within Europe that could adopt the liquid hydrogen powertrain. This would result
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Intersectional Faces of Labor Organization: Solidarity and Mobilizations in Logistics in Europe' under Horizon Europe.

assistant: **Concept**

The proposed action Intersectional Faces of Labor Organization: Solidarity and Mobilizations in Logistics in Europe (INFALA) aims to systematically examine the forms of solidarity, agency and labor organization of workers from the Middle East and North Africa (MENA) region, who have become increasingly present in European labor markets and in some countries are particularly visible in logistics. With few efforts engaging with labor on intersectional terms, and especially those from the MENA region who constitute the majority of those migrating to the EU, INFALA  investigates two contrasting cases among the largest economies in Europe of Italy and Germany with three objectives in mind: 1)Develop an analytical framework to analyze intersectionality, solidarity and labor’s agency and establish the contextual foundation by mapping trajectories of MENA migration to Italy and Germany, access to labor markets, visa regimes and bilateral agreements2)Conduct a three-layered interdisciplinary case analysis of the macro-(national) of Italy and Germany, meso-(sectoral) being logistics and micro-(worker) levels3)Compare these two case studies based on analytical framework to derive larger insights regarding (trans)national solidarity and larger labor movement The MSCA Postdoc Fellowship would be a crucial step for my career development, allowing to build on my knowledge in political economy to dive into the broad logistics sector to investigate the processes of intersectional and transnational solidarity building that innovate on, or depart from, more traditional class-based labor organizing in Europe. It would be hosted by the Scuola Normale Superiore (SNS) in Florence, which hosts the internationally-renowned ‘Centre on Social Movement Studies’ (COSMOS), under the supervision of P
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'SCIENCE MEETS CITY' (SCIENCEHOTEL).

assistant: **Innovation**

Science Hotel is a festival where the general public in Rotterdam and its region meets with scientific researchers and is introduced in their research and its relevance for daily life. The theme of Science Hotel is ‘Science Meets City’ featuring the relevance of research for many aspects our lives in an urbanized world, such as sustainability, health, digitalization, AI, security and privacy, transport and mobility, trade and employment. The festival facilitates personal and interactive encounters between the audience and researchers in the form of interactive lectures, games, demo’s, tours and simulations. It invites the audience to step into the daily life of researchers and discuss research topics and their perception by societal stakeholders with the researchers, emphasizing that everyone is co-creating science one way or another. Dialogue is stimulated, enriched and sometimes distorted, by artists’ interventions arranged by Science Gallery Rotterdam. Pre-events mediated by the Science Street promotion team take place all over town during the month of September on places where members of the potential audience are: cultural festivals, social cultural centers in the neighborhoods of Rotterdam and shopping areas. Special pre-events will be offered for school pupils in primary and secondary education. You’re invited. Check in to Science Hotel!


**Keywords:** RRI, Open Science, Science Festival, Co-creation. Public engagement in science
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Preparation and identification of new HIV reverse transcriptase inhibitors targeted against HIV strains resistant to anti-HIV/AIDS drugs' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

HIV-1 develops multidrug resistance in patients receiving various combination chemotherapies. To identify analogues active against HIV-1 drug-resistant strains, we plan to synthesize and investigate the structure, conformation and selected physico-chemical and biological properties of a range of new and known substituted with lipophilic groups, at 2, 4 and 3' positions 2',3'-dideoxynucleoside analogues. Compounds of this type should act as competitive drug-resistant reverse transcriptase (RT-Res) inhibitors.Other compounds to be synthesized and examined are new and known nucleosides from the group of 4'-C-substituted 2',3'-dideoxy-3'-fluoronucleosides. Slowly releasing forms of these compounds will be also prepared. Drug-resistant reverse transcriptases will be obtained from engineered HIV-1 drug-resistant mutants, as well as by recombinant techniques. Interactions of synthesized compounds with the wild type HIV-1 RT, as well as with HIV-1-Res RT, will be investigated.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Audio-VIsual Speech Processing for Interaction in Realistic Environments' under Seventh Framework.

assistant: **Concept**

The topic of audio-visual speech processing has attracted significant interest over the past 15 years. Relevant research has been focusing on recruiting visual speech information, extracted from the speaker's mouth region, as a means to improve robustness of traditional, unimodal, acoustic-only based speech processing. Nevertheless, to-date, most work has been limited to ideal-case scenarios, where the visual data are of high-quality, typically of steady frontal head pose, high resolution, and uniform lighting, while the audio signal contains speech by a single subject, in most cases artificially contaminated by noise in order to demonstrate significant improvements in speech system performance. Obviously, these conditions remain far from unconstrained, multi-party human interaction, thus, not surprisingly, practical audio-visual speech systems have yet to be deployed in real life. In this proposal, we aim to work towards expanding the state-of-the-art from the ideal “toy” examples to realistic human-computer interaction in difficult environments like the office, the automobile, broadcast news, and during meetings. Successful audio-visual speech processing there requires progress beyond the state-of-the-art in processing and robust extraction of visual speech information, as well as its efficient fusion with the acoustic modality, due to the varying quality of the extracted stream information. We propose to study a number of speech technologies in such environments (e.g., speech recognition, activity detection, diarization, separation), which stand to benefit from multimodality. The envisaged work will span 42 months of activity, and is planned as a natural evolution of research efforts of the candidate, Dr. Gerasimos Potamianos, while at AT&T Labs and IBM Research in t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Innovative biotech routes for efficient bio-based solvent production promoting a safe and sustainable European industry.', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The main objective of the SOLRESS project is to propose an integrated biorefinery system to replace the chemical origin of some of the most widely used solvents in the industry, such as ethyl acetate, ethyl lactate and butyl acetate with a bio-based origin from second generation sugars from post-consumer coffee grounds and lignocellulosic feedstocks. The aim is to reinforce the integration of bio-based research and innovation throughout industrial bio-based systems. Moreover, in the valorisation process of these feedstocks, not only the cellulose fraction will be valorised, but also the hemicellulose fraction to obtain 2 of the most notorious green solvents of today, 2-MeTHF and GVL, from an additional line dedicated to the processing of furfural.  The challenges will lie in improving downstream purification (DSP) processes and the techniques employed to achieve a technology that is efficient and cost-competitive with current chemical production systems for solvents.At the end of the project, all solvents will be validated in at least 3 of the most relevant applications (productive processes, formulations and recycling technologies) & at least 3 of the sectors with the greatest use of solvents (paints & coatings, cosmetics & materials processing) with the aim of evaluating its performance in comparison with its fossil-based counterparts, but also as a replacement for other dangerous and toxic solvents, such as NMP, CCL4, THF or toluene.Thus, the ambition of the SOLRESS project is triple:To replace the use of fossil, non-renewable raw materials with specific bio-based feedstocks in the production of some of the most widely used solvents.Offer SSbD alternatives to controversial solvents in terms of danger & toxicity (including the ones under the SVHC & SoCs categories).To