RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'New Bacterial Pathogens and Endosymbionts of the Olive Fly, Bactrocera oleae, for the  Development of Innovative Fruit Fly Biocontrol Strategies' (OliveFlyBacteria) targeting Horizon 2020.

assistant: **Abstract**

Olive oil production is of strategic importance for most economies around the Mediterranean. One of the main pests threatening olive cultivation is the olive fly. Related insects as the Mediterranean fruit fly and the invasive fly Drosophila suzukii are mayor problems in fruti- and viticulture. Given increasing limitations to the use of chemical insecticides, innovative biological control agents and IPM strategies for these pests are highly solicited.The applicant has previously established PCR tools for the specific identification of three bacterial insect pathogens that have recently been found associated with the olive fly. During his solicited research stay at CNR-IPSP Portici and planned secondments and short stays, these tools will be employed to explore olive fly populations across Southern Italy for new potential biocontrol resources. Targeted identification will be complemented by novelty-open exploration of olive fly microbiomes. The biocontrol potential of identified bacteria will be evaluated, and transposon mutagenesis together with PTR-MS and FISH will be used to identify virulence factors as toxins or chemical attractants. This research agenda can only be implemented in a cooperation of the applicant with an infrastructurally well established partner in a Mediterranean country as CNR-IPSP.It is the scientific-technical objective of the action to develop innovative biocontrol or IPM concepts based on the experimental results obtained.It is the strategic objective of the action:i) to identify new biocontrol strains not subject to property rights of third parties,ii) to create a regional network of biocontrol researchers, bio-insecticide producing SMEs, and olive cultivators to facilitate subsequent product development for a regional market, andiii) to incre
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Enantioselective Carbon-Fluorine Bond Formation: A Molecular Editing Approach toward Drug Discovery', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The unique properties of the carbon-fluorine (C-F) bond explain why organofluorine compounds play a central role in biopharmaceuticals. One current challenge in drug discovery is the selective installation of C-F stereogenicity within the active site of lead candidates, such molecular editing may greatly help in increasing potency and understanding metabolic degradation paths. However, the limited C-F bond formation techniques complicate this approach and providing new versatile catalytic techniques, which can expand the substrate pool amenable to C-F bond formation, would greatly boost the impact of fluorine chemistry in drug discovery. We aim at developing methods that require feedstock materials as substrates, such as alkene and alkane derivatives. The new methods will combine the potential of enantioselective organocatalysis or metal-mediated processes with visible light photocatalysis.The PHOTO-FLUOR project is unique in that it provides training in “enantioselective fluorination” and “catalysis applied to drug discovery”, areas that contribute to European excellence. The resulting techniques may immediately impact the EU Health sector. PHOTO-FLUOR will merge the expertise of the host group in photochemical enantioselective reactions with the background of the applicant in transition metal catalysis, to reach the desired deliverables and milestones. In addition, a secondment at an internationally recognized pharma-company has been included in the work plan for conducting biological study of the fluorine-edited bioactive molecules. The applicant will transfer knowledge to both host groups creating a link between them to forge future collaborations. Finally, an ambitious training program, which includes a number of new scientific and soft skills to be transferred to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Clocking fundamental attosecond electron dynamics' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The attoclock is a powerful, new, and unconventional tool to study fundamental attosecond dynamics on an atomic scale. We established its potential by using the first attoclock to measure the tunneling delay time in laser-induced ionization of helium and argon atoms, with surprising results. Building on these first proof-of-principle measurements, I propose to amplify and expand this tool concept to explore the following key questions:  How fast can light liberate electrons from a single atom, a single molecule, or a solid-state system? Related are more questions: How fast can an electron tunnel through a potential barrier? How fast is a multi-photon absorption process? How fast is single-photon photoemission? Many of these questions will undoubtedly spark more questions – revealing deeper and more detailed insights on the dynamics of some of the most fundamental and relevant optoelectronic processes.There are still many unknown and unexplored areas here. Theory has failed to offer definitive answers. Simulations based on the exact time-dependent Schrödinger equation have not been possible in most cases. Therefore one uses approximations and simpler models to capture the essential physics. Such semi-classical models potentially will help to understand attosecond energy and charge transport in larger molecular systems.  Indeed the attoclock provides a unique tool to explore different semi-classical models.For example, the question of whether electron tunneling through an energetically forbidden region takes a finite time or is instantaneous has been subject to ongoing debate for the last sixty years. The tunnelling process, charge transfer, and energy transport all play key roles in electronics, energy conversion, chemical and biological reactions, and fundamental proces
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Late medieval visionary Women's IMPact in early modern Castilian spiritual Tradition' (WIMPACT).

assistant: **Concept**

WIMPACT has two main objectives. In the first place, make an exhaustive research gathering the manuscripts and early printed books on/by European Late Medieval Mystic Women (13th-14th cc.) present in Castile in the premodern period (second half 15th c.-early 16th c.) and catalogue them. In the second place, evaluate the impact that those writings had, firstly, in the Castilian religious communities affected by Ximénez Cisneros Observant reform (1492-1517) and, secondly, in the Carmelite reform, accomplished by major literary figures as Teresa de Ávila and Juan de la Cruz (second half 16th c.). The first aim will be achieved by making an in-depth search in catalogues and directly in convent libraries of Castile and other institutions with keep collections related with female monasticism. In doing this, the ER will use his philological expertise combined not only to correctly classify the books, but also to understand them in a specific reception context. The results of this first phase will be accessible by the scientific community by creating an ad hoc open access webpage. The second aim will be achieved by implementing an interdisciplinary methodology which also departs from the comparative philology, but which uses tools of different fields (especially, gender studies, sociology and religious studies) to interpret the impact of those writings had in premodern Castile.The relevance of WIMPACT for Horizon 2020 is twofold: in the first place, it implies a comprehensive, transnational perception of the cultural history of Europe, which crosses traditionally established national and chronologic boundaries. In the second, it studies the empowerment of women, their subsequent influence in the politics of the Castilian court and the role that they had in the Observant reforms
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Chlamys: The cultural biography of a garment in Hellenistic Egypt' under Horizon 2020.

assistant: **Concept**

Hellenistic Egyptian history has been described as a 'tale of two cultures'. This duality is manifest in the differences between the textile cultures of the two ethic groups that came into contact during the time of the Ptolemies. The fundamental differences concern: a/ the traditional fibre used (linen in Egypt–wool in Greece); b/ the colour preference for garments (white for Egypt-a variety of vivid colours in Greece; c/ the loom used for weaving (horizontal in Egypt-vertical in Greece).  When Alexander the Great first came to Egypt, he decided to leave his mark on the territory, and founded the first city that would bear his name: Alexandria.  Descriptions of the city detailed by such later ancient authors as Diodorus Siculus, Strabo, Pliny the Elder and Plutarch report that the city had the shape of a chlamys, the typical woollen cloak of Alexander and his cavalry. The first chlamys-shaped wold map was also produced in Alexandria by Eratosthenes, head librarian at the famous library under the third Ptolemy. The founding of Alexandria inaugurates systematic cross-cultural interactions between Greeks and  Egyptians, two ethnic groups with distinct languages, cultures, ways of life, and, naturally, dress. The garment chlamys becomes the garment of Ptolemaic royals, while it continues to be the garment of the army. The make-up of this largely mercenary army, though, had since become ethnically diverse, and included local Egyptians. A host of sources (e.g. papyri, iconography on temples, tombs, ostraca, coinage) testify to the fact that the chlamys becomes widespread in both Alexandria and the rest of the Egyptian territory. This project investigates the garment chlamys both as a material object and as a cultural symbol, thus capturing multiple glimpses of everyday life
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Low Cost GNSS and Computer Vision Fusion for Accurate Lane Level Navigation and Enhanced Automatic Map Generation' (INLANE), addressing dissemination and exploitation.

assistant: **Impact**

Lane-level positioning and map matching are some of the biggest challenges for navigation systems. Although vehicle telematics provide services with positioning requirements fulfilled by low-cost GNSS receivers, more complex road and driver assistance applications are increasingly been deployed, due to the growing demand. These include lane-level information as well as lane-level navigation and prioritised alerts depending on the scenario composition (traffic sign, navigation instructions, ADAS instructions). These applications need a more accurate and reliable positioning subsystem. A good example of these new requirements can be witnessed in the increasing interest in navigation at lane-level, with applications such as enhanced driver awareness, intelligent speed alert and simple lane allocation. As well as the accuracy of positioning data being a big driver, there is also a question around the adaptability of navigation systems to these applications. This depends firstly on the availability of an accurate common reference for positioning (an enhanced map) and secondly, on the level of the provided pose estimation (integrity). However, neither the current road maps nor the traditional integrity parameters seem to be well suited for these purposes. Delivering lane-level information to an in-vehicle navigation system and combining this with the opportunity for vehicles to exchange information between themselves, will give drivers the opportunity to select the optimal road lane, even in dense traffic in urban and extra-urban areas. Every driver will be able to choose the appropriate lane and will to be able to reduce the risks associate with last-moment lane-change manoeuvres. inLane proposes new generation, low-cost, lane-level, precise turn-by-turn navigation applicati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Memory Compositional Abstract Domains:Certification of Memory Intensive Critical Softwares' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Every year, software bugs cost hundreds of millions of euros to compagnies and administrations. A number of disasters such as the Ariane 5 first flight failure can are due to faulty softwares. Static analysis aims at computing automatically properties of softwares, so as to prove they are exempt from some class of bugs. In the last ten years, static analysis of numeric intensive applications improved dramatically so that the certification of safety properties like the absence of runtime errors in industrial size control-command, numeric intensive applications, such as Airbus fly-by-wire softwares is now feasible.By contrast, the situation is much worse for memory intensive softwares. Existing static analyzers for such softwares do not scale to large scale softwares, and fail to prove strong invariants on large classes of softwares. These limitations stem from the fact they use a monolithic algebra of logical formulas (or abstract domain).Our proposal is based on the observation that the complex memory properties that need be reasoned about should be decomposed in combinations of simpler properties. Therefore, in static analysis, a powerful memory abstract domain could be designed by combining several simpler domains, specific to common memory usage patterns. The benefit of this novel vision is twofold: first it would make it possible to simplify drastically the design of complex abstract domains required to reason about complex softwares, hereby allowing certification of complex memory intensive softwares by automatic static analysis; second, it would enable to split down and better control the cost of the analyses, thus significantly helping scalability.This shift of focus will bring both theoretical and practical improvements to the program certification field. We pro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Heparanase inhibition as a multifunctional targeting approach in cancer' (HEPINIB), addressing dissemination and exploitation.

assistant: **Impact**

Cancer is a leading cause of mortality within the aging European population. Therapeutic targeting is hampered by the complexity of the disease, which includes not only molecular changes within the tumor cell itself, but also within its microenvironment. Tumor angiogenesis, tumor-stroma interactions, interactions with immune cells, with the extracellular matrix and cancer stem cell nichesallow for malignant cell survival and promote metastasis, the leading cause for cancer-associated mortality. Proteins substituted with the heparin-related carbohydrate heparan sulfate (HS) are dysregulated in malignant diseases, and are known to modulate all of the aforementioned processes of tumor progression. Several functions of HS-PGs in tumor progression are modulated by the enzymeheparanase (HPSE), which is barely expressed in adults, but upregulated during tumor progression, inflammation and angiogenesis, thus constituting an excellent drug target. Indeed, HPSE, the sole HS degrading endoglycosidase, regulates multiple biological activities that enhance tumor growth, metastasis, angiogenesis and inflammation. HPSE accomplishes this by degrading HS and thereby regulating the bioavailability of heparin-binding proteins, priming the tumor microenvironment and mediating tumor-host crosstalk. We predict that therapeutic targeting of HPSE to be superior to conventional approaches, as it does not only have the potential to synchronously targeting tumor progression and metastasis at multiple levels (metastasis, angiogenesis, inflammation & immunity), but it is also be expected to have a favourable side effects profile. HEPINIB will combine leading experts of HPSE-related cancer research with non-academic partners providing a panel of innovative technologies with the aims of providing a d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Centre of excellence on application of plasmas and pulsed-power technique'.

assistant: **Innovation**

The main objective of the proposal is to enhance capacity of the IPPLM and to speed up its integration to European Research Area. The objective will be achieved by:- intensive networking with leading European laboratories,-creation of the leading training site in the field of plasma physics, pulsed-power technique and their applications,-organisation of thematic workshops (3), school and training courses for young physicists on modern diagnostic methods and computer modelling,- mutual study visits of young as well as experienced scientists,- organisation of international experiments on unique facilities operating at the IPPLM,-common activity in the field of applications of dense magnetised plasma in medicine (PET diagnostic), material science, defectoscopy etc., organisation of a consortium to prepare and submit project for FP-6.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'CHromospheric magnetic fields in fLAREs and their evolution'.

assistant: **Concept**

This research project aims to study the variations of the solar magnetic field in flares, the most energetic events in our solar system. Flares accelerate charged particles into space, which may adversely affect satellites and Earth’s technology. Despite their clear importance for today’s technology, the timing and positioning when flares occur are so far unpredictable. Changes in the solar magnetic field topology are known to be the causes for flares, but their physics is not understood in detail. Past studies have shown prominent changes of the magnetic field in the photosphere during flares. But higher in the atmosphere, in the chromosphere, studies are scarce because ground-based telescopes with special instrumentation and capabilities are needed. No space mission has been or is being planned with capabilities for those chromospheric magnetic measurements. The most suitable spectral range to study the upper chromosphere is the He I 1083.0 nm triplet and the project has access to two unique data sets of high-energetic flares in this spectral region. Since there are no diagnostic tools for this prominent spectral triplet in flares, the first goal is to upgrade an existing tool (spectral-line inversion code) to include flare physics. The code will be made freely available for the benefit of the scientific community, so that it can be used to analyze future flare observations in this wavelength range. The second aim is to use the upgraded tool to infer for the first time the evolution of the magnetic field vector in the two abovementioned data sets. The results will provide thresholds for the shear/ twist of the field lines that lead to the analyzed flares. Hydrodynamic simulations and satellite data will complement the results to simulate the atmospheric response to th