RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The role of SOcial ecoNomY in Addressing social exclusion, providing quality jobs and greater sustainability' (SONYA).

assistant: **Concept**

With a growing aging population, the EU faces increased demand for quality social elderly care. However, intricate legal and policy landscapes for Social Economy organizations (SEs) contribute to poor working conditions, gender bias and innovation challenges, hindering the provision of sustainable and inclusive social services by SEs. This is particularly exacerbated in rural areas, where access to facilities and technology deployment and logistics is complicated. The EU context is facing the urgent need for affordable services and to rethink the dominant recipient model of social care, which challenges the sense of dignity, identity and quality of life of both elderly people and care givers. SONYA emerges as a pioneering initiative to assess the role of SEs in retaining and attracting social elderly care workers to foster social innovation effectiveness in rural areas. Our vision seeks to scale up SEs successful activities beyond tool, support services and methods development by empowering SEs to develop participatory multi-actor networks and social and environmental community initiatives, identifying and transferring social innovations for inclusive employment and better working conditions while measuring impact with scientific precision for improving legal and policy frameworks supporting SEs. SONYA is implemented by a consortium of scientific partners with expertise in operationalising multi-actor participatory models, sustainability assessment, workers' rights and effective representation, and policy making; enabling entities representing 3 EU SEs models varying in size, network development and national context; and support actors. SONYA will facilitate a transition towards more respected, inclusive and valued social elderly care services, beyond medical care. Targ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Cosmological challenges in theories of extra dimensions' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

The conjecture that there exist in nature extra (i.e. more than four) dimensions, is well motivated theoretically and promises surprising experimental signatures when the extra dimensions and quot;open up and quot;. Liberating our universe from four dimensions, offers new perspectives to long-standing problems of high-energy physics and cosmology. My research project will focus on three areas of interest in the cosmology of extra dimensions. Firstly, I will study the explanation of the smallness of the vacuum energy of the Universe (i.e. the cosmological constant problem) through extra dimensional theories. Secondly, I will study the cosmology of the moduli fields, corresponding to the sizes and shapes of the extra dimensions, mostly in relation with their stabilization. Thirdly, I will study the extra dimensional models, which predict modifications of gravity at large distances, as an alternative to the dark energy paradigm. In the above studies I will work on the theoretical consistency of the theories and propose possible observational signals.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The Role of Host, Genetic and Environmental Factors on Biochemical Markers in Workers Exposed to Butadiene' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

To study in the workers exposed to 1,3-butadiene the interindividual variability in the production of haemoglobinbutadiene monoepoxide adducts. To develop new methods to include in the biomonitoring analysis also adducts generated by butadiene-diepoxide. The metabolism of 1,3-Butadiene (BD) involves the formation of the more toxic epoxides 1,2-epoxy-3-butene (BMO) and 1,2,3,4-diepoxybutane (DEB). Several drug-metabolising enzymes are involved in this metabolism, including cytochromes P450 2E1 and 2A6, in the formation of epoxides, and glutathione transferases M1 and T1, in the detoxification of the epoxides. The ratio between the activating and the deactivating enzymes are of great importance for the toxicity of BD. Since all the four enzymes mentioned above are polymorphic in humans, large interindividual differences in the formation of toxic metabolites of BD probably exist. Since this wide interindividual variation of internal exposure and of biomarkers, like haemoglobin adduct, has already been demonstrated, butadiene exposure represent an interesting model situation to investigate the role of pharmacokinetic parameters for individual susceptibility. In this respect the following studies are proposed, after having build up a cohort of workers exposed to butadiene and controls (environmental exposure), controlled for possibly confounding factors and well characterised as far the exposure is concerned:1.Measure of mercapturic acid of BD, as indicator of internal dose, and of BMO in the blood;2. Development of methods to analyse (a) plasma protein adducts of butadiene-monoepoxide, (b) plasma and haemoglobin adduct of butadiene-diepoxide.3. Determining the genotype of polymorphic enzymes CYP2E1, CYP2A6 and glutathione transferases. The levels of adducts determined and t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Real-time Early Detection and Alert System for Online Terrorist Content based on Natural Language Processing, Social Network Analysis, Artificial Intelligence and Complex Event Processing' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The RED-Alert project will bring data mining and predictive analytics tools to the next level, developing novel natural language processing (NLP), semantic media analysis (SMA), social network analysis (SNA), Complex Event Processing (CEP) and artificial intelligence (AI) technologies. These technologies will be combined for the first time and validated by 6 law enforcement agencies (LEAs) to collect, process, visualize and store online data related to terrorist groups, allowing them to take coordinated action in real-time while preserving the privacy of citizens. The RED-Alert solution will outperform state-of-the-art solutions in terms of number of languages supported, privacy-preserving capabilities, usability, detection performance, real-time capabilities and integration capabilities. The RED-Alert approach combines for the first time the CEP methodology with NLP/SMA and SNA applications in the context of social media data analytics, transforming (unstructured) social media data into (structured) events enhanced by semantic attributes. For example, a tweet will be an event consisting of content (expressed as NLP features e.g. concepts, sentiment, entities, etc.) and context (time and the author including SNA features e.g. number of followers, number of links, etc.). Turning unstructured social media data into structured events is key, as it allows the system to use (event) rules (event temporal logic, event logic patterns, even counting, absence of events) to infer insights or create alerts in real-time.The project impact is supported by the participation of Europol and specific dissemination activities around the World Counter-Terrorism Summit, organized by one of the partners. The total requested EC funding is 5M Euros and the project duration 36 months.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'From Meaning to Perception: How narratives shape visual processing' (VisualNarrative), addressing dissemination and exploitation.

assistant: **Impact**

Humans constantly generate expectations of what will happen in the future. Such expectations allow us to quickly absorb incoming data. For example, the visual system takes advantage of the world’s relative stability over space and time to anticipate upcoming input. However, most of what we currently know about predictive visual processing comes from studies using arbitrary associations between simple stimuli, such as gratings or abstract objects, which do not reflect the richness of daily life events. It is largely unknown how more complex, meaning-based expectations influence visual processing. To overcome this barrier, the proposed project will use an ecologically valid paradigm, using picture books, and investigate how such more complex, narrative-based expectations shape visual processing. I hypothesise that narratives will elicit strong expectation signals that impact even the earliest levels of sensory processing. To test this hypothesis, I will first quantify narrative-based expectations derived from the picture stories using state-of-the-art computational modelling. Then, I will assess whether these expectations shape the processing in visual cortical regions of adult human volunteers, using neuroimaging. I will inspect whether such signals become anticipatory as viewers become familiar with the narrative – in line with the idea that upon construction of a world model, the brain predicts upcoming stimuli. Moreover, I will also investigate what brain regions shape such learning of narratives. In a separate eye-tracking experiment, I will explore how narratives influence gaze behaviour, providing another assay into how meaning percolates to visual processing. This project will allow me to conduct creative, original and important research, which will propel my scie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Medicine Made to Measure.' (MMM) under Horizon Europe.

assistant: **Objectives**

Modern medicine seeks to personalize diagnosis and treatment to the needs of individual patients. This need is heightened in particular for those individual patients where no treatments are available – and where current standard treatment development paradigms exclude to generate such. The ultimate goal of Medicine made to Measure (MMM) is to go even beyond the latest genetic medicine approaches, implementing a novel paradigm of treatment development:  the field of single patient tailored antisense oligonucleotide (ASO) treatments for patients with nano-rare disease mutations. Specifically, MMM will develop core modules of a novel “out-of-the-box”, but still EMA-advised treatment development path for these patients - from omics-based theranostics, via preclinical target validation to innovative trial methodology and a pioneering ethical framework for individualised genetic therapies. MMM provides a unique opportunity for doctoral candidates to be involved in building - and to receive training - in all core modules needed for tailored ASO treatment in Europe. This new scientific field requires a new generation of open-minded, technology-fluent and applications-oriented experts. MMM will help educate future drug development and translational experts in adopting and disseminating such a cross-specialty approach. Our idea for this innovative training network is built on our personal experience and understanding of the importance of single patient tailored genetic treatments in the years to come. We propose a consortium of world-leading experts and partners that present with extended experience and relevant know-how in molecular biology, neurology, translational medicine, biochemistry, bioinformatics, philosophy, mathematics, regulatory science and engineering. Thus, MMM pro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Highly-Efficient Seeded Frequency Comb Generation on a Chip', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Generating new colors (frequency components) of light through nonlinear optical phenomena is one of the key drivers of modern optical technology. The spectrally diverse coherent light, widely known as an optical frequency comb, can be produced through a nonlinear process. The optical frequency comb enables energy-efficient optical communication, precision spectroscopy, and optical atomic clock. However, the frequency comb sources currently rely on bulky and power-hungry laser systems hampering their deployment outside the laboratory environment. There are great demands in lowering the size, weight, and power (SWaP) of such broadband light sources. Despite the significant progress in the miniaturization of comb systems and microcomb technologies. it is still a huge challenge to drive a broadband (larger than an octave) comb with microwave repetition rate using on-chip pump sources due to the limited performance of on-chip lasers. The COMBCHIP project aims to develop an ultra-efficient comb generator by combining the highly nonlinear AlGaAs waveguide and a newly developed seeded pumping scheme. The developed comb sources feature an octave-spanning bandwidth, microwave repetition rate, and ultra-low operation power, enabling chip-scale comb systems in emerging applications such as atomic optical clocks in satellites and mid-infrared spectroscopy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Mass Manufacturing Augmented Reality (AR) Waveguides via Roll-to-Plate Nanoimprinting' (AR), addressing dissemination and exploitation.

assistant: **Impact**

Morphotonics has developed and patented a novel technology called Roll-to-Plate (R2P) nanoimprinting that can produce high-quality and low-cost waveguides used in the Augmented Reality (AR) glasses. Our technology is protected by 90 patents (26 already granted). Augmented Reality (AR) smartglasses are not yet mass manufactured for the consumer market especially because the AR industry struggles to mass produce low-cost high-quality waveguides. Our technology is very promising, as confirmed by our prestigious sampling customers (Microsoft, Meta, Apple, Vuzix etc.). With the EIC project, we want to fully mature our equipment and technology, and prove (via an external validation with a customer) that it meets the market specifications. Furthermore, we plan to request a 10 M€ equity component to set up a European foundry to mass manufactur AR waveguides. We expect that the foundry will be used mainly by European customers, who will then regain sovereignty over the AR hardware production.


**Keywords:** Nanotechnology
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Investigating how pathogen effector recognition by the host plant activates cell death' (HRPCDMECH) targeting Horizon 2020.

assistant: **Abstract**

Plants are rich sources of nutrients and water for diverse microbial communities. Some of these communities evolved parasitism as a strategy to access plant nutrients, with devastating results for crops. Plants are protected from infection by a waxy cuticular layer above the walls of epidermal cells. Would-be pathogens breaching this barrier, or entering via stomata, encounter an active plant immune system that specifically recognizes pathogens. Breaching leads to the deployment of two synergistic pathways that orchestrate immune responses. The first relies on the detection of pathogen-associated molecular patterns (PAMPs) and culminates in pattern-triggered immunity (PTI). When the first is circumvented a second array of responses takes place known as effector triggered immunity (ETI). In ETI, host factors known as R proteins recognize pathogen effectors, an event which is accompanied by the execution of a unique programmed cell death (PCD) type known as the hypersensitive response (HR). Although the initiator of the HR-PCD is known to depend on the formation of an effector-R complex, the downstream molecular events remain elusive. Previous results showed that particular proteases known as metacaspases (MCs) modulate HR-PCD, highlighting the importance of proteolysis and proteome rearrangements for HR-PCD modulation. I will attempt to shed light on the rearrangements of the HR-PCD proteome landscape, by studying processes that control it: selective RNA decapping and translation and proteolytic events, in a highly temporal manner using systematic approaches and reverse genetics. This project is expected to elucidate the importance of these processes and provide a detailed analysis of mRNA and protein level rearrangements during HR-PCD. In addition, this project will sug
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Developmental Origins: exploring the Nature-Nurture Interplay' (DONNI).

assistant: **Concept**

The “Developmental Origins of Health and Disease” (DOHaD) hypothesis states that insults in early life can have lifelong, irreversible impacts, affecting individuals’ health and well-being in older age. My proposed research builds on this in two main ways. First, I will use natural experiments to investigate the causal impact of early life circumstances on later life outcomes, focusing on novel (1) nutritional, (2) toxicological, (3) health and (4) economic environments in early life. Within these, I will consider insults (i) for which there is insufficient knowledge of their long-term impacts, (ii) which are relevant today, and (iii) importantly, which are modifiable. Second, I will go beyond the old “nature versus nurture” debate and investigate how individuals’ genes (‘nature’) interacts with the above early life environments (‘nurture’) in creating inequalities in health and well-being.Whilst neither the estimation of causal effects within DOHaD, nor the estimation of the gene-environment (GxE) interplay is new, their combination is. Indeed, it is currently not known how the early life environment interacts with genetic predisposition to causally shape later life outcomes, as well as whether certain environments exacerbate or reduce health inequalities in the population. Combining advancements across disciplines, I will evaluate the long-term effects of short-term variations in early life conditions (objective 1), and I will directly test the hypothesis that gene-environment interactions causally shape later life outcomes (objective 2). I will digitize historical data on early life environmental exposures and merge these with large-scale individual-level data. As such, my proposal will investigate the extent to which genes interact with the environment, using natura
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Next-generation Plasma-based Electron Beam Sources  for High-brightness Photon Science', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

High-quality electron beams are required for advanced light sources and for high energy physics. Engines of discovery such as free-electron-lasers (FELs) and other bright light sources, are driven by electron beams today produced in km-long state-of-the-art linear accelerators (linacs). A complementary alternative are cm-scale plasma-based accelerators, which are feasible in university-lab scale environments. The NeXource project aims at combining key advantages of both types of accelerators to realize hybrid plasma-based accelerators orders of magnitude smaller and at the same time with electron beam quality orders of magnitude better than state-of-the-art. This has far-reaching impact as it will enable the construction of table-top coherent hard x-ray sources with extreme brightness. This project is motivated by experimental breakthroughs obtained in the E210 collaboration at the linac-driven plasma accelerator facility FACET at the Stanford Linear Accelerator Center (SLAC) and by the progress at laser-plasma-accelerator facilities, combined with novel conceptual approaches towards beams with unprecedented 6D-brightness by using tailored beamloading in plasma-based photocathodes. A dedicated setup for plasma photocathode prototyping and hybrid plasma acceleration will be established at the Scottish Centre for the Application of Plasma-based Accelerators (SCAPA) to develop beam brightness transformers. This R&D will be complemented by campaigns at SLAC, DESY, Daresbury Laboratory and laser-plasma-accelerator labs in Europe. Start-to-end simulations indicate that hard x-ray FELs with ultrahigh gain and other advanced light sources can be realised with such electron beams in university-scale labs, which would have transformative impact on photon science and a wide range