RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Water and Energy for Life in Libya'.

assistant: **Concept**

The WELL project aims to strength the capacities of the General Water Authority while turning it into an international centre of excellence, and reinforcing the cooperation capacities and research activities in Libyan’s water and energy sectors by defining research priorities in water and energy to respond to socio-economic needs, facilitating participation in the European water and energy research initiatives and inclusion in the European Research Area. Considering the actual crisis in Libya, WELL project represents a model to overtake “standard” CSA project, pointing out the importance of the Governance inside the “Triple Helix” (Policy, Research and Business) in Libya and fostering capacities of GWA to participate at FP7 Calls.The specific objectives of WELL project are:•Better Coordination Between Policy, Research and Business in Libya•Enabling Better Participation in Framework Programmes•Enhancement of EU-LIBYA S&T Partnership in Energy and Water Research•Capacity Building for Solving Specific Energy and Water Issues•GWA’s Strengthening and Cooperation Capacities Reinforcement•Energy and Water Research Results Dissemination•Fostering innovation in Libya through active participation of SMEs in FP7•Increase job opportunities that encourage gender equality in Libya, in particular for young scientistsThe main impact of WELL will be increased capacities of the GWA centre and the structuring and enhancement of the existing EU-Libya support landscape in Energy and Water S&T cooperation through a fourfold way: (i) by proposing a Research-focused Triple Helix Governance Model to enhance stability in the Country, (ii) by supporting the participation of Libya in the FP7 and other EU related initiatives, (iii) knitting together all relevant support schemes, and (iv) facilitati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Genuine Quantum Algorithms Inspired by Thermodynamics and Natural Phenomena' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

As low-noise medium-scale quantum devices are on the horizon, it is becoming increasingly important to find useful quantum algorithms that can be run on such devices. However, existing quantum algorithms typically only offer an advantage compared to advanced classical computers when run on large-scale quantum devices for rather long running times, urging us to find more effective quantum algorithms.This project aims to design new efficient Nature-inspired quantum algorithms and find new applications and use cases, through quantum generalisations of the Metropolis algorithm and Glauber dynamics, whose classical counterparts were also distilled from deeper understanding of physical models and thermodynamical processes, but turned out to be foundational in computer science through applications to a wide range of problems outside their original scope. The primary focus is on quantum algorithms related to open quantum systems and thermalisation. Such algorithms can be described by Quantum Markov Chains (QMC), which unify the powerful paradigms of classical randomized algorithms and traditional coherent quantum algorithms. Due to their rich, complex structure such processes have proven to be hard to construct and analyse. The PI's recent breakthroughs in designing detailed-balanced QMCs opened new ground in quantum algorithms design, and the PI intends to explore and exploit the resulting QMC algorithms and adapt them to the requirements of early quantum devices.The PI's interdisciplinary approach already led to the successful translation of the physics inspired ""Quantum Signal Processing"" protocol to a major unification of various quantum algorithms via ""Quantum Singular Value Transformation"" (QSVT) (which has been presented at STOC'19 and cited 750 times since). Further
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Catalytic and asymmetric carbonyl epoxidation'.

assistant: **Objectives**

Research objectives and content The host group has previously discovered a novel catalytic cycle for epoxidation of carbonyl compounds using just catalytic quantities of sulfides, metal salts, and diazocompounds (this work was patented by Zeneca). In order to make this process less hazardous, the in situ generation of the diazocompounds has been considered and indeed found to be successful. However, none of the simple chiral sulfides based on oxathianes have worked in the catalytic process and so new classes of chiral sulfides need to be prepared to render this practical, catalytic cycle asymmetric. Once we have found simple chiral sulfides that are effective, we will scale up the process and demonstrate its applicability to the preparation of a broad range of epoxides. In essence, the process constitutes the coupling of two aldehydes to give epoxides with control over relative and absolute stereochemistry and that is atom economical and powerful. This process will also be applied to asymmetric aziridination. Training content (objective, benefit and expected impact) The chemistry involves the use and handling of sensitive reagents and therefore provides excellent training in careful experimentation. Furthermore, the work will require the use of the all of the most up-to-date analytical techniques and so will provide comprehensive training. The chemistry described could become one of the best methods for the direct preparation of epoxides and this will have a major impact both in academia and industry. Links with industry / industrial relevance (22) The host laboratory has strong links with industry (they currently collaborate with 8 different chemical companies) and Sheffield University will be patenting this work if it is successful. Epoxides are intermediates in an in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Glycoprotein-based inhibitors of shiga-like toxin' under Horizon 2020.

assistant: **Concept**

Gastrointestinal infections have substantial impact in both the developing world and in Europe with 1.5 billion cases each year leading to approximately two million deaths each year, 760,000 of which are in children under five years old. Many of these deaths are caused by bacteria for example E. coli O157, that produces protein toxins, including shiga-like toxin (SLT). In the human body, the surfaces of living cells are covered in complex carbohydrate molecules. This “sugar coating” allows the cells to interact with viruses, bacteria, and toxins that have complementary protein receptors. The pentagonal shiga-like toxin produced by E. coli O157 bacteria can attach to five copies of a specific carbohydrate on the gut wall and enter cells lining the intestine. The result is bloody diarrhoea and the toxin entering the circulatory system to cause kidney failure.In this project, we will make protein-based inhibitors that can prevent this toxin from attaching to, and enter kidney cells. The inhibitors will be synthetic glycoproteins that have 5 copies of the target sugar attached at specific sites so that they can bind to all 5 of the toxin’s receptor sites simultaneously providing an extremely strong interaction to prevent the toxin from entering cells. During the project we will synthesise a series of glycopeptides and attach them to pentameric protein scaffolds using site specific chemical and enzymatic modification. We will evaluate the glycoproteins as inhibitors of toxin adhesion and cell entry using a variety of cell and biophysical assays. The optimized inhibitors will have potential as a new class of future biopharmaceuticals.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Researchers and Citizens Night' under Seventh Framework.

assistant: **Concept**

RaCeN results on the work develop between 12 French partners that for the second time work on only one project to have a bigger impact on the public. It is not only an event, is a preparation, discussion with all partners before the venue, and it is an observation, an analysis of the different proposition after the 25th September. The aim is to offer large public and researchers an unique opportunity to directly meet and get closer to one another. Events will be organised in the cities of Strasbourg, Mulhouse, Besancon, Dijon, Lille, Rennes, Brest, Bordeaux, Toulouse, Angers, Montpellier, Nimes, Lyon as well as Paris and the region Ile de France. All the events will focus on the researchers as human beings: their will act advisers during the hands on experiments and demos, will be available to all the potential questions raised by the audience and in particular share with the public interests and fun, and act as normal citizens" while unveiling the magic of their work to the participants. We chose to mobilize the PhD student to show them the necessity to discuss with citizens, to prepare these researchers of tomorrow to participate at the debate science and society, and to show at young visitors that their big sister or brother engage in a career in research."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'New Materials and Control for a next generation of compact combined Solar and heat pump systems  with boosted energetic and exergetic performance' (MACSHEEP).

assistant: **Innovation**

The objective of this project is to develop new innovative products and advanced test methods for a next generation of compact combined renewable energy systems based on solar thermal and heat pump technology for space heating and hot water preparation, using breakthroughs in ICT, new materials and technology. The goal is to achieve 25% energy savings compared to current state of the art systems, with still competitive prices on the market. Thus, the work proposed aims for a seasonal performance factor of the system (solar and heat pump) of e.g. 6 as compared to 4.5 for the current state of the art. This will be possible by using new materials, components and ICT in an integrative approach for new system concepts where the focus is on the overall system's cost and performance. A systematic approach will be used to evaluate new breakthroughs such as e.g. low-cost materials and selective paint for solar collectors that collect solar irradiation as well as ambient heat and PV/T collectors that produce heat as well as electricity. Exergetic optimization of heat pump circuits includes using de-superheating heat exchangers for DHW preparation as a by-product of the more efficient space heating operation, and variable speed controlled compressors for heat pumps that match the collector heat input to the evaporator and/or the demand. New storage concepts include phase change materials (PCM) on the cold side of the heat pump, low cost materials for storage tank construction, improved temperature stratification and charging/discharging control. On the control and ICT side, weather and user forecast based predictive control for intelligent storage charging by different heat sources will help to increase the overall system performance significantly. Online monitoring and fault dete
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Learning to enhance exploitation potential of SME project results' in the context of a Horizon 2020 call.

assistant: **Objectives**

SMEs highly benefit from successful research that results in applicable solutions. It is either by monetizing their own innovative solutions or by cooperating with a research organization and bringing the shared results onto the market or other space for exploitation. In order to help this process by employing public funding and supporting activities, it is important to be able to detect and evaluate exploitation potential in research projects that are to receive the support. The partners of this project are public organizations supporting applied research by funding and assistance. They believe that in order to positively influence the research-driving SMEs and research-implementing SMEs, it is essential to be able to evaluate projects from the perspective of exploitation (or in other words application) potential. Specifically, it is key to be able to, first of all, select the most promising project proposals for support (the proposals with the highest exploitation potential) and, second, help them to successfully finish their projects and implement their results by interim and ex-post monitoring complemented with support services. Therefore, this project’s goal is to build a peer-learning group and share each other’s best practices and experiences and apply them in practice in order  to improve project partners’ proposal-evaluation and project monitoring skills in terms of exploitation potential. This improvement could lead to higher success rate of the projects and their better impact assessment (Alves Ribeiro, 2015). Finally, the project also has a goal to disseminate its results among other research and innovation supporting organisations in Europe.


**Keywords:** exploitation potential, application of research results in practice, application potential, SME, eval
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The First Responder (FR) of the Future: a Next Generation Integrated Toolkit (NGIT) for Collaborative Response, increasing protection and augmenting operational capacity' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Today’s First Responders (FR) are using technology of the past. During their primary mission of saving lives and preserving society’s safety and security, FRs face a multitude of challenges. In both small scale emergencies and large scale disasters, they often deal with life-threatening situations, hazardous environments, uncharted surroundings and limited awareness. Threats and hazards evolve rapidly, crossing municipalities, regions and nations with speed and ease. Armouring public safety services with all the tools that modern technology has to offer is critical. Such tools holistically enhance their protection and augment their operational capacities, assisting them in saving lives as well as ensuring their safe return from the disaster scene. INGENIOUS will develop, integrate, test, deploy and validate a Next Generation Integrated Toolkit (NGIT) for Collaborative Response, which ensures high level of Protection & Augmented Operational Capacity to respond to the disaster scene. This will comprise a multitude of the tools and services required: 1) for enabling protection of the FRs with respect to their health, safety and security; 2) for enhancing their operational capacities by offering them with means to conduct various response tasks and missions boosted with autonomy, automation, precise positioning, optimal utilisation of available resources and upgraded awareness and sense-making; 3) for allowing shared response across FR teams and disciplines by augmenting their field of view, information sharing and communications between teams and with victims. The NGIT armours the FRs at all fronts. The NGIT will be provided at the service of the FRs for extensive testing and validation in the framework of a rich Training, Testing and Validation Programme – of Lab Tests (L
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'SYNchrony in Caregiver-Child Interactions across Neurodiversity' (SYNCC-IN).

assistant: **Innovation**

This project aims to boost sustainable collaboration in a cross-national and cross-disciplinary network, with the University of Warsaw as the widening partner, the University of Heidelberg University of Milano, Copenhagen University, and the University of Trento to facilitate knowledge transfer and exchange of best practices in the research on biobehavioral synchrony. Research exploring how different synchrony measures are related to each other in diverse populations seems highly important, as biobehavioral synchrony is known to support health and psychological well-being. The main goal of the SYNCC-IN project is to strengthen the University of Warsaw's scientific and organizational capacity and to make the University of Warsaw a leading player in biobehavioral synchrony research. The SYNCC-IN project is formed by five universities carefully selected for their complementary expertise in biobehavioral synchrony. It will establish a Virtual Laboratory for Biobehavioral Synchrony led by the University of Warsaw. Leading researchers in the field with complementary expertise and experience in strategic areas will collaborate on this project. The group will develop a protocol to study different levels of synchronization in parallel (behavioral, physiological, neural). Subsequently, this protocol will be applied in a multicenter research project. The transfer of knowledge between partners is vital to this project. Work packages include sustaining changes at the University of Warsaw, conceptual framework building for parent-child synchrony, methodology transfer and integration, joint study, dissemination and outreach, and management and coordination. Twinning funds will help make the Widening Country’s University of Warsaw an important research center within the designated fiel
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Single-cell temporal tracking of epigenetic DNA marks' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Over the past decade, epigenetic phenomena have taken centre stage in our understanding of gene regulation, cellular differentiation and human disease. DNA methylation is a prevalent epigenetic modification in mammals, which is brought about by enzymatic transfer of methyl groups from the S-adenosylmethionine (SAM) cofactor by three known DNA methyltransferases (DNMTs). The most dramatic epigenomic reprogramming in mammalian development occurs after fertilization, whereby a global loss of DNA methylation is followed by massive reinstatement of new methylation patterns, different for each cell type. Although DNA methylation has been extensively investigated, key mechanistic aspects of these fascinating events remain obscure. The goal of this proposal is to bridge the gap in our understanding of how the genomic methylation patterns are established and how they govern cell plasticity and variability during differentiation and development. These questions could only be answered by precise determination of where and when methylation marks are deposited by the individual DNMTs, and how these methylation marks affect gene expression. To achieve this ambitious goal, we will metabolically engineer mouse cells to permit SAM analog-based chemical pulse-tagging of their methylation sites in vivo. We will then advance profiling of DNA modifications to the single cell level via innovative integration of microdroplet-based barcoding, precise genomic mapping and super-resolution imaging. Using this unique experimental system we will determine, with unprecedented detail and throughput, the dynamics and variability of DNA methylation and gene expression patterns during differentiation of mouse embryonic cells to neural and other lineages. This project will give a comprehensive, time-reso