RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Multiscale Numerical Methods for Inverse Problems Governed By Partial Differential Equations' under Seventh Framework.

assistant: **Concept**

Inverse problems that are governed by partial differential equations arise in many applications in computational science and engineering. Solving these large scale problems is a real challenge to the existing numerical methods, as they are generally highly ill-posed and non-convex. These difficulties are usually handled by introducing statistical Bayesian estimation methods that promote a-priori knowledge to the problems. Such methods address the uncertainties in the inverse problems, such as the noise and unknown parameters, so that the solution of the inverse problems is meaningful and realistic. Additionally, numerically solving these large-scale problems requires highly efficient and scalable numerical methods, which are still missing or inadequate for many applications.Multiscale and multigrid methods are extremely efficient and scalable for some applications, but there are other problems that still pose severe challenges. In this research I plan to study two problems: one is the challenging inverse wave equation, which appears in many applications such as seismic exploration of reservoirs, and medical imaging. The other problem is the rather unexplored 4D imaging of flow in porous media, used for monitoring of reservoirs, carbon sequestration among other applications. I plan to develop efficient multiscale (and multigrid) methods for some of the key ingredients of the numerical solution of these problems. Such methods may enable a scalable and efficient solution of these inverse problems. In particular, to solve the inverse wave equation, one needs to efficiently solve the Helmholtz equation, which is still considered an open question. Another example is a multiscale approach for efficiently estimating an inverse of a covariance matrix given a few measurements. Th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Low cost and environmentally safe process for recycling municipal solid waste incineration ashes' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

The present project aims at creating a cheap and effective system, based on Low Temperature Sintering/High Energy Milling, capable of stabilising and recycling ashes derived from MSW incinerators, obtaining, from such residues and from recycled glass derived from MSW collection: 1. Ceramic Pellets, to be used as active surfaces in the gas cleaning treatment needed in MSW Incineration or Power Plants (100% of the residual would be recycled) 2. A dramatic ash volume reduction (30%) ; 3. The total absence of waste streams, either gaseous, liquid or solid 4. The savings in use of natural sources to manufacture ceramic products for industrial application; 5. The absence of Green Gaseous Gases emission in the process
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Genomic in fish and shellfish: From research to aquaculture' (AQUAGENOME) under Sixth Framework.

assistant: **Objectives**

In recent years, a relatively large number of projects investigating the biology of aquaculture species through genomic approaches have been funded both at European levels and national levels. These have generated an extensive core of genomic tools and expertise that is spread among European research laboratories.  However, this scientific resource is not coordinated within research and transfer to the European aquaculture industry is still in its infancy. In this context, the objectives of AQUAGENOME are  (i ) to coordinate the ongoing and future national and international research projects in the field of genomics in fish and shellfish European aquaculture and support diffusion of genomic approaches within research laboratories  (ii) to enhance the transfer of information and knowledge towards the aquaculture industry. In order to reach these objectives, the aims of this project will be: -  To inventory existing genomic resources and identify and evaluate new bioinformatic resources, genomic information and tool s that are vital for the development of European aquaculture.  - To identify specific research domains in which genomic approaches should be developed in order to support the European aquaculture industry.  - To support exchanges of scientists and genomic re sources between members of the AQUAGENOME Associated Partner Network created.  - To determine the required actions to apply genomic tools and knowledge in an effective and sustainable manner in aquaculture, by interacting with producers and stakeholders.  These achievements will require the use of a number of instruments, e.g. working groups to gather experts in specific domains, organisation of workshops where aquaculture industry will meet research and construct a roadmap for genomic transfer to industry
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Nanomesh - Boron Nitride Nanomesh as a Scaffold for Nanocatalysts, Nanomagnets and Functional Surfaces' (NANOMESH).

assistant: **Innovation**

The NanoMesh project is based on the recent discovery by one of the proposing groups of a spectacular nanostructure of hexagonal boron nitride that self-assembles on a rhodium metal surface [M. Corso et al., Science 303, 217 (2004)]. It is a supported, m esh-like structure consisting of two atomic layers with a periodicity of 3.2 nm and holes of about 2 nm. The relevance of the project to the thematic area 3.4.1.1 is twofold. With roughly 400 boron and nitrogen atoms in the mesh unit cell, the self-assem bly process is truly remarkable, and it is accessible to live observation by surface science techniques, including scanning tunneling microscopy under process conditions. By elucidating the self-assembly mechanism in this highly non-trivial case, the pro ject is very likely to provide new and general insight in this efficient and cheap type of nanostructure formation. The second key point of relevance lies in the nature and the stability of the boron nitride nanomesh. It is inert and stable up to 1000 K, and it thus lends itself perfectly as a template or scaffold material for forming secondary nanostructures. Metal deposition on the nanomesh is expected to produce highly monodisperse metallic nanoclusters that represent prime candidates for catalysts w ith high activity and selectivity, or for nanostructured magnets with superior magnetic or spintronic properties. The edges around the pores of the mesh permit the stable covalent attachment of organic or even biological molecules of desired functionali ty, thus leading to well structured functional surfaces. The attachment of large molecules should lead to higher hierarchies of self-assembling supramolecular structures that should be very interesting for biotechnology applications. In full expectation of these applicati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'AQUAculture infrastructures for EXCELLence in European Fish research', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

AQUAEXCEL will coordinate the highest class European aquaculture research facilities covering the entire range of production systems (recirculation, flow-through, cage, hatchery and pond systems), environments (freshwater and marine, cold and warm water), scales (small, medium and industrial scale), fish species (salmon, trout, sea bass, sea bream, cod, carp…), and fields of expertise (nutrition, physiology, health and welfare, genetics, monitoring and management technologies and engineering).AQUAEXCEL will:- Link and coordinate key research infrastructures in Europe: cage, recirculation and hatchery aquaculture systems, land and sea based, fresh and salt water installations in order to create the basis for synergistic research projects- Provide research teams with access to a wide range of the state-of-the-art infrastructures covering all important aquaculture species, systems, environments and expertises- Increase resource sharing and standardization between partners, notably but not exclusively for fish models and experimental methods developed in-house- Stimulate innovation through transfer of knowledge, harmonisation and development of best practices across fields of research, production systems and species- Execute joint research and development activities designed to improve the services currently provided by the infrastructures (remote access and monitoring, more accurate performance evaluation, limitation of live animals use, applicability of results at industry scale, development of biological models).- Bridge the gap between the scientific community and the industry through stimulation of problem-based research and enhanced knowledge transferAQUAEXCEL will facilitate a coherent development of the aquaculture research facilities for which there is a strong dem
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Scanning Tunneling Microscopy - Modeling Defects and Adsorbates onSemiconductors and Insulating Films'.

assistant: **Innovation**

This research deals with modeling of Scanning Tunneling Microscopy (STM) and Spectroscopies (STS) in studying defects and adsorbates on ultrathin insulating films and semiconductor surfaces. Theoretical modeling of STM is a necessary part in interpreting e xperimental data, and also in planning future experiments. The objectives of this research project are twofold. First, this project will serve as further training for a post doctoral researcher, Dr. Sami Paavilainen, to prepare working as an independent re searcher. The second objective is to develop and utilize different methods in analyzing the STS and STM experiments. The methods will include density functional theory calculations, tight-binding model and models for elastic and inelastic tunneling in diff erent tunneling junctions.Insulating films on metal surfaces can be studied with STM if they are thin enough. Thin insulating films are also interesting due to their prospects in nanotechnology where the decoupling of adsorbates from the metal could be uti lized, e.g., in production of nanocircuits. The modeling of STS of these films is complicated, since defect and adsorbate states form a double barrier tunneling junction.For semiconductors, our interest lies in the Cross-sectional STM (X-STM) which allows one to study formation of defects and segregation in epitaxial growth of compound semiconductors. Because STM probes contours of a constant LDOS, heterointerfaces made of different types of atoms on the opposite sides are revealed by image contrast. Modeli ng these subtle effects requires also combining different methods.The group has a wide cooperation with top-class experimental STM groups in Europe. In addition, collaboration inside the local university has a significant role in this project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Qur'anic Commentary: An Integrative Paradigm' (QuCIP) targeting Horizon 2020.

assistant: **Abstract**

QuCIP will deliver the first historical-critical commentary on a sizable portion of the Qur’an in English, covering the three longest and most complex compositions in the Islamic scripture, surahs 2–4, as well as the short opening surah 1. The project will thereby put forward a pioneering proof of concept for an integrative exegetical approach capable of addressing three core dimensions of the Qur’an: the compositional structure of Qur’anic texts, the intricate processes of literary growth and redactional expansion by which many of them have been shaped, and the theological concerns governing the Qur’an’s appropriation of antecedent (especially Jewish and Christian) ideas, traditions, and literary forms. Pre-modern Islamic exegesis will be critically scrutinised as a valuable repository of close scriptural reading, even if its premises and conclusions are not always persuasive to a modern historian. The result will be a paradigmatic benchmark transforming the methodological toolkit of the discipline.In realising this ambitious project, the PI will be supported by three postdoctoral scholars. Two of them will undertake foundational research into the Qur'an's compositional grammar and into Qur’anic law. The third postdoctoral researcher will support the PI’s engagement with the voluminous Islamic exegetical literature and write a reception history of surah 4. The project team will furthermore produce an edited volume or special journal issue.


**Keywords:** Qur'an, Islam, scripture
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Synthesis of the antitumour macrolide spongistatin 1' (1994-1998) under Fourth Framework.

assistant: **Objectives**

Research objectives and content The aim of this project is the exploration of new synthetic routes which would lead to the total synthesis of the important | antimitotic agent spongistatin 1. In the course of this work several synthetic methodologies, mainly chiral aldol reactions, already developed at the host research group would be applied. In addition, there would be a need for the development of new . methods which would be also suitable for a general application in Organic Synthesis. The objective of this project could be extended towards the preparation of synthetic analogues of the natural product in order to test their biological and pharmacological activities. Training content (objective, benefit and expected impact) The fulfilment of this project would improve the research training received by the applicant during his Ph.D. period in the field of Organic Synthesis, and would be useful for a future work in EU Universities or industries. Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Structural analysis of the CSA binding interactions involved during pregnancy associated malaria' (PREMALSTRUCT).

assistant: **Innovation**

Adhesion of Plasmodium falciparum-infected erythrocytes (PE) to placental chondroitin-4-sulfate (CSA) has been linked to the severe disease outcome of pregnancy-associated malaria (PAM). After multiple pregnancies, women acquire protective antibodies that block CSA-binding and cross-react with geographically diverse placental isolates suggesting that surface molecule(s) expressed by PAM-infected erythrocytes have conserved epitopes and that a PAM vaccine may be possible. Recent evidence strongly suggests that var2CSA, a member of the P. falciparum Erythrocyte Membrane protein 1 (PfEMP1) family, may have an important role in PAM and immunity. Although var2CSA and to some extent var1CSA are the main candidates for a pregnancy malaria vaccine, experimental evidence implies that antigenic polymorphism and the lack of a small animal in vivo experimental model may pose a challenge for vaccine development. To date, efforts to develop a truly prophylactic PAM vaccine have been hindered by the difficulty in identifying immunogens that elicit broadly neutralizing and adhesion-blocking antibodies. Accordingly, a small number of highly specialized and experienced malaria research groups from Europe (6 groups) and endemic countries (2 groups) have decided to give highest priority to decipher the molecular basis for the CSA binding to the parasite ligands in order to define the common features within the different CSA-binding domains and the cross-reactive epitopes that are likely to be the targets of natural protective antibodies. This knowledge will not only be very helpful in the design of novel PfEMP1-CSA based antigens capable of inducing broad and potent neutralising antibodies to a wide variety of strains, but also to identify molecules with inhibitory capacity that could be c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Advanced numerical methods to study interactions in colloidal systems' (CAL4COLL).

assistant: **Innovation**

The interactions between colloidal particles determine stability of colloidal systems, phase behaviour of concentrated suspensions and their viscoelastic properties. Also the short-range interactions between particles and interfaces are the driving force for the adsorption (deposition or adhesion) of nano- and colloidal particles. Effective adsorption of colloid and bioparticles is important for many practical processes. Learning about mechanisms of adhesion of colloids is also relevant for polymer science, biophysics and medicine.The main scientific objective of this project is the development of effective numerical methods for studying of electrostatic interaction in a variety of colloidal systems. These methods will be based on the solution of the non -linear Poisson-Boltzmann (P-B) equation, which governs the distribution of ionic charges around colloid particles. The methods developed for two- and three-dimensional P-B problem will be specifically applied to study many-body interaction between particles. In particular the problem of interaction of colloidal particles at the vicinity of the charge wall, which is crucial for understanding colloid adsorption phenomena will be considered.The results of theoretical modelling will be confronted with experiments performed on model colloidal systems under controlled transport conditions. The collaboration initiated during the project will be long lasting, since, with increase of computing power, the modelling of the colloidal interaction is scientifically very broad and expanding field. It can have also high technological potential facilitating to produce the suspensions with desired properties.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'A genomics approach to increasing disease resistance in dairy cows through improvements in innate immunity' in the context of a Seventh Framework call.

assistant: **Objectives**

Our hypothesis is that genetic selection for high yielding dairy cows has been associated with reduced innate immune responses. This predisposes cows to common diseases such as mastitis and endometritis, reducing fertility and decreasing longevity. We propose that this trend could be reversed by identifying key genes involving innate immune function and selective breeding of more robust cows. The research objectives are: (1) to perform genome wide association studies  to identify regions associated with relevant health traits; (2) to use comparative genomics to identify candidate genes associated with innate immune responses; (3) to test endometrial responses to lipopolysaccharide in cells with up- or down-regulated expression of a candidate gene involved in innate immunity; (4) to sequence selected candidate genes in different cattle populations to discover novel single nucleotide polymorphisms (SNPs); (5) to validate the relevance of these genes in association studies with disease in two new populations of UK and Chinese dairy cows and (6) to perform a functional validation study on blood cell responses to bacterial pathogens in cows with differing genotypes for the selected candidate genes. The project combines the expertise of Huazhong Agricultural University, China (HZAU) and the Royal Veterinary College, UK (RVC) in farm animal genetics and genomics, dairy cow production and the innate immune system. The objectives will be met by the mobility of Professor SJ Zhang to the UK, when she will work closely alongside a team of four RVC scientists led by Professor DC Wathes and share with them her experience of selection for disease resistance. A return phase will support a validation study and transfer results back to HZAU. Both groups have worked together before, are e