RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Pan-European Access for man. SME on tech. services for clean production through a Network of premier KET Technology Centres with one stop shop access incl. EEN and discourse with policy makers on RIS3' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

A multi-KET (key enabling technologies) approach is most beneficiary for SME in regard to increase in productivitiy, efficiency and market shares. To enable a Pan-European Access for SME on technology services for clean production, a network of premier KET Technology Centres with facilitated one stop shop access, offering SME multi-ket infrastructures and services across borders on pan-european level is generated, involving innovation consultants from the Enterprise Europe Network (EEN) being local = at the doorstep of EU`s manufacturing SMEs. Due to the disparity of KET TC in EU28, KET4CleanProduction (KET4CP) enables also a discourse with policy makers on RIS3 and the potential of cross-border collaboration to cover specific SME needs for clean production technologies.KET4CP starts with 12-premier KET TC and 7 EEN as an open innovation ecosystem, with a one stop shop access. KET facilitators support the SME in identifying their specific technology challenge for clean production, propose services and technologies based on innovation potential + need analysis. The fast, flexible services focus on the SME´s business case.After a pilot phase with 20 SME innovation projects/micro grants, the network is scaled up adding 17 KET TC and 21 EEN members, to reach a critical mass of CP technology deployment in SME. Targeted actions stimulate initial requests of >120 SME from > 10 EU MS and a total of 70 SME micro grant projects with min. 140 KET TC. 2 MEUR third party financing go to SME in total. 50 % are targeted for low to modest innovator regions.KET4CP delivers standard procedures / tools for KET TC transnational collaboration and joint service/shared infrastructure, based on business model scenarios stimulating KET TC to collaborate and share clients. KET4CP creates a susta
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Ecmarnaprod' (ECMARNAPROD).

assistant: **Innovation**

Natural Products Research has become a key discipline of the life sciences. The development of new pharmaceuticals and of crop protecting agents heavily relies on the discovery and understanding of novel molecules capable of specifically interacting with living organisms. In the infective disease and cancer areas, the share of natural product-related compounds exceeds 60 % of the newly approved drugs. Science has to answer, e.g. to the upcoming antibiotics crisis exemplified by the resistance of certain tuberculosis-causing bacteria against -lactam antibiotics and even vancomycin. The understanding of the chemical interactions between organisms is mandatory for progress in ecology.The world's oceans compose over 70% of the earth's surface and 90% of the volume of its crust. Over the past 30 years, sessile invertebrates, algae, and marine microorganisms have proven to be rich sources of novel, biologically active natural products. Important examples already brought to the market include the anti-inflammatory pseudopterosins and, recently, ecteinascidin 743 as anti-cancer agent. Although European research facilities are excellent, the vast majority of scientific contributions originate from research groups located in the USA and in Japan. The European research activities in Marine Natural Products Chemistry have to be further strengthened. The proposed conference will be characterized by the intense discussion of a large number of young, talented researchers from Europe with experienced, internationally renowned scientists from universities and industry. To ensure the maximum benefit for the younger participants, all of the following, major research topics in the interdisciplinary field of Marine Natural Products Research will be addressed: isolation and structure elucida
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'algorithmic methods for optimizing the railways in europe' to be submitted under Fifth Framework.

assistant: **Abstract**

Objective: to provide young researchers with methods and techniques to face real problems arising from European railway systems by an interdisciplinary training in the area of computer science, mathematics and traffic engineering. Individual training: based on exchanges of young pre- and post-doctoral researchers. The pre-existing collaborations among teams will allow a fast and productive start of exchanges. Young researchers carry out individual activities under the supervision of a senior researcher. When required, they will receive a specific training on software instruments and development tools and will be partially involved in the organization of the main events as well as in project management. Interaction with industries will be managed under the existing national contact points. Common training: based on Network Meetings (NM) and Training Institutes (TI). A NM is a small conference with general talks, talks on special subjects, and strategy discussions. A TI consists of a school and a workshop. The school consists of lectures on open problems and tutorials. It will initiate joint research projects of young and senior researchers within a specific topic. The workshop is devoted to discussions and joint research.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'ground-breaking PEROvskite technologies for advanced X-ray medical Imaging Systems' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The PEROXIS project will develop a new X-ray imaging system with higher sensitivity and spatial resolution compared to conventional ones, which will support diagnosis during intervention and treatments of various diseases.The emerging semiconducting perovskite materials, largely used for photovoltaic applications, are a good candidate since they have the potential to globally address the following ambitious objectives:-Advancing X-ray based imaging systems for advanced diagnostics and treatments of two major diseases: cardiovascular disease (CVD) and stroke-Improving the efficiency and spatial resolution of flat panel X-ray detectors-Groundbreaking perovskite-based direct conversion X-ray imaging detectors for large-area compatibility-Validating the improved image quality of cone beam computed tomography (CBCT) in stroke detectionPEROXIS is a multidisciplinary project engaging 7 EU partners from 4 countries (France, Germany, Spain and the Netherlands) covering the academic, RTO and industrial (3 major medical equipment manufacturers) worlds. An implementation plan is presented in the form of 8 work packages, 6 of which are technical in nature. Synergy in communication and dissemination by the several partners and stakeholders (external advisory board mainly composed of physicians who provide letters of intent) will permit to maximize the PEROXIS project impact.Both solutions to overcome the fundamental technological barriers as well as appropriate deliverables, tasks, milestones and risks in order to complete the project objectives in due time are presented. The medical sector will be highly impacted by the PEROXIS project outcome: future applications of an improved PEROXIS imaging system will not be limited to stroke and CVD only, but may be extended to various other c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Beta-cell inflammation and dysfunction induced by bacterial translocation' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Type 2 diabetes (T2D) has risen to epidemic proportions resulting in major morbidity and mortality. In addition to insulinresistance (i.e. impaired insulin action), impaired function and destruction of the insulin-producing beta cells form the directcause for hyperglycemia and T2D, and causes the progressive course of disease. As such, due to continuous beta-celldestruction, many patients require treatment with exogenous insulin therapy. Clearly, therapies that may halt or reverse thisdetrimental process are warranted.An inflammatory process in islets of Langerhans, with infiltration of immune cells and a central role for toll-like receptors(TLR), is present in T2D, however, the primary trigger for this inflammatory response remains unknown. Recently, (diet-induced)alterations in intestinal microbiota composition were shown to associate with T2D. In addition, T2D patients haveincreased translocation of detrimental bacteria (‘leaky gut’), previously shown to induce adipose tissue inflammation anddysfunction.Recently, I hypothesized that increased bacterial translocation to the pancreas induces inflammation and beta-celldysfunction in T2D through TLR related mechanisms. I addressed this hypothesis first by identifying translocated microorganismDNA in pancreatic tissue harvested during pancreatectomy in patients with and without T2D. In pilot data, I havedemonstrated increased bacterial load in patients with T2D as compared to control patients. The involved micro organismswith highest pathogenicity will be (an)aerobically cultured and subsequently used in gavage studies in a obese mouse model with or without a knockout for TRL4 to study their effects effects on beta-cell function, glucose metabolism and pancreas inflammation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Field -testing and demonstration of digital and space based technologies with  agro-ecological and organic practices in systemic innovation' (PestNu).

assistant: **Innovation**

PestNu targets the field -testing and demonstration of digital and space based technologies (DST) and agro-ecological and organic practices (AOP) under a systemic approach to reduce the pesticides and fertilisers use, and loss of nutrients. The consortium brings novel DST including: AI robotic traps for real time pest monitoring; Autonomous mobile robots for pesticide monitoring and 3D spot spraying; Earth Observation missions with robust Agroradar AI algorithms to map soil/plant nutrients and pest plant inputs using Copernicus data/services; and in-situ and real-time nutrient analysers. All the DST will be interconnected to a user-centric cloud-based Farm Management System, which features a robust Decision Support System integrated with a blockchain based system for DST data evidence, integrity and AI models verification and with a cybersecurity platform to prevent cyber-attacks and IoT vulnerabilities. The AOP include: on-site production of biofertilisers from agricultural waste-waters through a robust automated drainage recycling system via an innovative enzymatic hydrolysis procedure; a novel foliar biopesticide formulated by circular bioeconomy operations, targeting fungal diseases with biostimulant effect; and advanced nutritional programs for organic farming. The showcase systemic DST & AOP solutions will be demonstrated and tested in aquaponic and hydroponic greenhouse and open-field vegetable cultivation in Greece and Spain. A Pesticide Reduction Program will evaluate the Maximum Residue and the Acceptable Daily Intake levels to ensure vegetable's food safety and LCA activities will be performed. All these systemic approaches will be performed under a strong collaboration among all the Farm to Fork stakeholders and European Commission services.


**Keywords:**
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Hydration Dynamics of Antifreeze Proteins'.

assistant: **Innovation**

Antifreeze proteins (AFPs) and antifreeze glycoproteins (AFGPs) enable the survival of various organisms in freezing or subfreezing habitats. Even millimolar concentrations of these proteins are sufficient to lower the freezing temperature by several degrees. To reach a similar freezing point depression using sodium chloride would require molar concentrations. Nowadays AF(G)Ps already find applications in food industry, for instance to prevent recrystallization in ice cream and have great potential in medical applications (cell & organ storage, operations at low temperature). Protein-water interactions are of general interest owing to the importance of protein hydration for protein function; AF(G)Ps form an extraordinary example of this coupling that is sufficiently strong and specific that the protein controls macroscopic thermodynamic properties of water. Despite their importance in nature and their industrial relevance, the mechanisms by which AF(G)Ps depress the freezing point are still poorly understood. Although substantial information presently exists on the static protein structures and thermodynamic properties of these systems, molecular scale information on the dynamics of the conformations of the AF(G)Ps, their hydration shells and their binding to ice, is extremely scarce. Here we propose to study the molecular mechanisms by which AF(G)Ps lower the freezing temperature with advanced nonlinear spectroscopic techniques like 2D polarization-resolved vibrational spectroscopy and surface sum-frequency generation. These techniques enable the label-free study of the structural dynamics of the AF(G)P conformations, their hydration shells and their mechanism of binding to the ice surface. They will be used to study several key elements in the functioning of AF(G)Ps.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'New ICT infrastructure and reference architecture to support Operations in future PI Logistics NETworks' under Horizon 2020.

assistant: **Concept**

ICONET will significantly extend state of the art research and development around the PI concept in pursuit of a new networked architecture for interconnected logistics hubs that combine with IoT capabilities and aiming towards commercial exploitation of results. ICONET strives to achieve the end commercial goal of allowing shipments to be routed towards final destinations automatically, by using collaborative decisions inspired by the information centric networking paradigm, and optimizing efficiency and customer service levels across the whole network. According to this vision, cargo regarded as smart physical packets will flow between hubs based on ‘content’ of the cargo influencing key commercial imperatives such as cost, optimisation, routing, efficiency and advancing EU's Green agenda.  Consequently, the consortium are discernibly aimed at three (3) avenues of commercialisation and exploitation from the ICONET innovation, specifically targeted in the areas of (a) Warehousing as a service, (b) E-commerce fulfillment as a service, and (c) Synchromodality as a service.PI based logistic configurations will be simulated, prototyped and validated in the project . Modelling and analysis techniques will be combined with serious game type simulation, physical and digital prototyping, using living lab (LL) requirements scenarios and data. With analyses and simulations, optimal topologies and distribution policies for PI will be determined.  The project implementation will be based on a succession of phases of modelling and design/prototyping, learning and experimentation and feedback and interaction with the wider business community, including the ALICE logistics platform as well as members of the partner Associations ESC, UIRR and ELUPEG.  Through  its Living Labs, the pro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Nanostructured anode catalyst layer for oxygen evolution reaction based on a novel thin-film architecture' under Horizon 2020.

assistant: **Concept**

The transformation of energy coming from renewable sources into gas with the purpose of storage and transportation (power-to-gas) is a powerful approach for the development of new-generation secure, clean, efficient energy systems. Key step in such a process is electrolysis, which utilizes electrical current for splitting water into oxygen and hydrogen. While the present electrolysis technology (anion exchange cells) is insufficient for covering the future demands, polymer-based cells (PEMECs) represent an emerging alternative for becoming the key-enabling technology in power-to-gas systems.  Thin-CATALYzER aims at making an important step towards the implementation of PEMECs at large scale by introducing an innovative paradigm based on thin-film technology for the fabrication of an efficient, durable and sustainable PEMEC anode catalyst layer. This will serve both as an end-product possessing a high level of technological readiness and as a platform for achieving new information on the fundamental reaction mechanisms.  Thin-CATALYzER tackles the current limitations of PEMEC anodes as it takes advantage of a single-step physical deposition process (PLD) for obtaining a nanostructured catalyst layer with high level of purity and of noble metal utilization, optimized meso- and microstructure, to be deposited on ceramic single crystals or on a commercial support according to the needs.  Besides, the project comprises a program for the professional growth of the ER by training-through-research in catalysis and related techniques and for the development of complementary skills. This will be achieved thanks to the commitment of the host institution and of the action partners (academic and industrial), which possess a highly qualified and intersectorial knowledge. Lastly, the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Bioconductive Iongels for Cutaneous Electrophysiology'.

assistant: **Objectives**

Bioelectronics is limited by the materials that transducer signals across the interface between biology and electronics. For example, in cutaneous recording, the interface between the electrode and skin is the key parameter to get a good recording. For these applications, there is a great deal of interest in developing soft conducting coatings that decrease the impedance between the electrode and the skin. Hence, the interface between the skin and the electrode is improved allowing an easier flow of the ionic and electronic current. Although hydrogel based electrolytes are in use, the continuous evaporation of water does not allow the long-term cutaneous recording. The current proposal is aiming at exploring innovative materials such as iongels that can enhance the ionic conductivity and decrease the impedance with the human skin without suffering evaporation during the recording due to the negligible vapour pressure of ionic liquids. These cutaneous electrodes will be used to monitor the electrical activity of specific organs for a better understanding of the physiology and the pathology of different organs.The Marie Skłodowska-Curie Individual Fellowship will open the best career possibilities for Dr. Ana Sanchez. After a successful PhD and 2 year post-doc in polymer chemistry in the University of the Basque Country in Spain, she decided to move to a different environment where she can exploit all her materials science expertise. The Department of Bioelectronics in EMSE directed by Prof. Malliaras in Aix-en-Provence (France) is one of the top-class groups in the emerging area of bioelectronics, where the electronics and biology converge. This multidisciplinary environment not only will broaden the scientific knowledge of Dr. Ana Sanchez in a hot topic such as bioelect