RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Development of an innovative high-performance railway wheelset (HIPERWHEEL)' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Design of rolling-stock is facing new severe specifications, due to the increased severity of the train mission: some cases of unusual service failures have recently occurred to the wheel set (the axle-wheels assembly), with a remarkable impact on train safety. Moreover, to enhance the environment quality nearby the rail net, the need of reducing the radiated noise is recognised, for which the wheel rail contact noise is highly responsible. Therefore, the aim of the projects the development of an innovative wheel set having outstanding safety and low noise performances. The wheel set design will be based on integrated CAE methodologies, implementing tools for vibro-acoustic and durability analysis specifically developed within this project. Relevant deliverables of the project will be full-scale demonstrators showing significant weight reductions and satisfying both safety and low noise requirements.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Systematic study of gene silencing in transgenic plants, characterisationand use of the sequence-specific signal involved', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Research objectives and content Gene silencing is a major limitation to the reliable use of genetically engineered crops. Although extensively described, it is still poorly understood because of the complexity of the chromosomal factors affecting the transgene expression. I have recently developed a straightforward and reproducible system for consistent activation of gene silencing based on transient expression of foreign sequences in transgenic Nicotiana benthamiana plants (transiently induced gene silencing: TIGS). This novel approach takes advantage of the induction of a previously unknown signalling mechanism in plants that mediates sequence-specific systemic gene silencing. I will use transgenic non-silenced Nicotiana benthamiana plants carrying the jellyfish green fluorescent protein (GFP) gene as a model system for TIGS, in order to systematically address the following points:What are the features that make the foreign sequence able to initiate GFP gene silencing ? What is the nature of the signalling molecule ? How is the signal propagated/ maintained in the plant and what type of cells are affected by TIGS ? In addition, TIGS may provide a new tool for analysis of plant gene function and, eventually, for control of plant gene expression. These aspects will also be investigated. Training content (objective, benefit and expected impact) This project is of major interest to me for the following reasons: -it gives me the opportunity to broaden my knowledge in modern biological techniques and to work on a previously unknown aspect of plant biology that may be of considerable importance in our understanding of plant genetic regulation. -this work will be carried out in a laboratory that is in the forefront of not only the study but also the practical use of gene sile
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The role of the vav proto-oncogene product in cell signalling' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

vav is a proto-oncogene expressed solely in hematopoietic cells. The protein has an array of structural features which suggests its participation in signal transduction. The analysis of mice deficient in vav expression (vav-- ) has shown the essential role of this proto-oncogene in T and B cell proliferation. The downstream signalling molecules associated with VAV are mostly unknown. The main objective of this proposal is the identification and functional role of transducing molecules interacting with VAV. Toward this goal I propose to use the two-hybrid system which I master. This aproach is specially suited for detecting newly interacting proteins. The validity of them can be demonstrated by in vitro aproach (i,e. fusion protein) and by in vivo experiments (coimmunprecipitation of the newly detected protein). The two-hybrid system has an added advantage: it permits to delimitate domains of the proteins responsible for the interaction. From my initial screen of the Iymphoid cell cDNA library with SH3/SH2/SH3 domains of VAV as bait, I have worked close to a 15% of the true positives. I have shown that nuclear proteins Ku-70, and probably RNP C, associates with VAV. I propose to evaluate the functional role/s of these interactions by different aproaches and to investigate changes of these interactions in resting and activated hematopoietic cells. We expect that these findings might help in understanding the function/s of VAV. To detect newly interacting proteins with VAV, I propose to characterize the remaining positives from my initial screen. We have evidences that an interaction of VAV and Grb2 exists by the two hybrid aproach and also in intact cells. This prompted my interest to investigate the interachon of a naturally occuring isoform -Grb3.3- which cannot bind ty
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'School Food Environments' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

Obesity rates have nearly tripled since the 1980’s in the United States and in many European countries, and this rise has been particularly alarming with regards to children. To combat childhood obesity, policy makers have increasingly been examining school food environments. School food environments are defined as policies enacted by a school affecting students’ dietary intake during the school day. The proposed project will evaluate various consequences of three distinct school food environment components. The first policy is the ban of carbonated beverages in schools, and the analysis will ask whether household compensation in response to these bans - already observed in my ongoing research - varies based on household characteristics or how long it has been since the ban was initially introduced. The second policy is the provision of healthier school lunches, and I will evaluate the effect the provision of healthier school lunches in a Northern California school district had on student test scores and fitness outcomes. The third school food environment component is whether high schools grant their students the privilege to go off campus during the school day, which exposes these children to food purchasing options outside of school. This analysis will extend upon my previous research on open/closed campus policies concerning their effect on academic outcomes and will examine the effect on student behavior outcomes and fitness outcomes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'SIlicon Optomechanical optoellectronic Microwave Oscillator' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

High-quality microwave sources are required in multiple applications (radar, wireless networks, satellites, etc.). Typically, low-noise microwave oscillators are made by applying frequency multiplication to an electronic source. This requires a cascade of frequency-doubling stages, which strongly reduces the power of the final signal. Recently, different techniques to produce microwave tones via optical means have been proposed. The resulting device is an optoelectronic oscillator (OEO), with many advantages with respect to its electronic counterparts (immunity to EM interference, low weight, compactness, long-distance transport, etc). In the FET-Open project PHENOMEN, partner UPV designed and demonstrated a novel optomechanical cavity on a silicon chip displaying, for the first time, a localized mechanical mode at frequencies around 4 GHz within a full phononic bandgap and with a large OM coupling rate. By pumping the cavity with a blue-detuned laser, a high-Q microwave tone at f = 3.874 GHz is created at driving power of the order of 1mW. The noise figure of this OEO becomes as low as -101 dBc/Hz at 100 kHz, which is a remarkable good value for an OEO oscillating at GHz frequencies without any feedback mechanism. In addition, stronger pumping of the cavity enables the generation of multiple harmonics, thus reaching microwave frequencies above 10 GHz. Therefore, with the advantages of extreme compactness and Silicon-technology compatibility, this approach is a very promising candidate to build ultraweight OEOs, highly appropriate for space applications. Notably, the use of photonic technologies in space is one of the main activities of partner DAS.SIOMO aims at turning a silicon-photonics optoelectronic oscillator based on cavity optomechanics - recently demonstrated i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'The Reforming Spirit in the Age of Revolutions: The Counts of Bernstorff, Commercial Monarchy, and the Invention of Modern Liberty', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

This project offers the first comprehensive account of the Counts of Bernstorff and the part they played in the making of enlightened reforms in eighteenth-century Denmark. Through a detailed study of the personal and intellectual networks of Johann Hartwig Ernst von Bernstorff (1712-1772) and his nephew Andreas Peter von Bernstorff (1735-1797), two reform-minded Hanoverian counts, who served as chief ministers to the Danish monarchy, REFORMARCHY reconstructs a series of intellectual exchanges between Copenhagen, Geneva, and Gttingen. In so doing, the project elucidates the efforts of the Bernstorffs to reform the Danish monarchy in view of contemporary challenges to the European states system and recovers their main contribution to Enlightenment thought, that is, their vision of modern liberty in a commercial monarchy. Drawing on intellectual currents introduced to them through the various centres of their networks, this vision was moulded by such diverse languages as republicanism, monarchism, natural law, cameralism and political economy. The main objectives of the project are thus to map the personal and intellectual networks the Bernstorffs, to analyse the key concepts of their political vision, and to examine the imperial response to global commercial competition that underpinned their enlightened reform programme. Reconstructing the reforming spirit of the Counts of Bernstorff, REFORMARCHY not only makes an innovating contribution to historical scholarship on enlightened reform, it also brings into view the historical and conceptual relationship between freedom and the state. By returning the concept of modern liberty to its eighteenth-century origin in the dialogue between republicanism and monarchism, REFORMARCHY offers a novel perspective on our current politi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Intelligent Cooperative Sensing for Improved traffic efficiency'.

assistant: **Concept**

The architecture of the ICT infrastructure for supporting Intelligent Transportation Systems (ITS) is purely hierarchical, with sensed data flowing from the leaves (i.e., road-side or vehicle-installed sensors) to the root (i.e., the traffic management centre). The current approach does not scale adequately with the inclusion of a significant number of new elements, is not flexible in supporting an incremental growth or changes of the ITS, and exhibits latency and security issues. In ICSI we tackle all these issues by proposing a new architecture where the intelligence for sensing and actuation is distributed over some of the elements, called gateways, which host a software platform for running ITS applications, using the local storage and computation capabilities available. Communication with the remote centre happens only for the transmission of aggregated data for long-term operations, e.g., data mining, software upgrades, and logging.The approach proposed in ICSI enables scientific and technological innovations: advanced sensing algorithms will be defined, which make use of real-time availability of data; efficient distribution of context-rich data lays the foundations for novel traffic and travel management strategies. Both directions will be studied in the project. However, research challenges are associated at all levels to the realization of the system, especially for the communication among sensors, gateways, and vehicles, which are fully addressed in the project activities. Prototypes of sensors, road-side units, and communication units suitable for the cooperative operation envisaged in ICSI will be developed and integrated into an end-to-end demonstrator, which will be used in on-field experiments for the use cases of smart urban traffic management and accid
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Investigating the contribution of the sensory visual cortex for REpresentation and STORagE during visual working memory.' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Visual working memory (VWM) is the cognitive process responsible for temporarily maintaining in mind visual information that is no longer in view. The neural architecture of VWM has been of continuous scientific interest and it has been proposed that the sensory visual cortex is involved in the brain network responsible for successful REpresentation STOragE during VWM. However, the contribution of the sensory visual cortex in VWM remains a subject of intense debate, underscoring the need for a decisive investigation. RESTORE aims to shed light on this debate. Through a three-way transfer of knowledge, RESTORE will lead to contemporary methodology, by combining transcranial magnetic stimulation (TMS) with electroencephalography (EEG), resulting in a robust and cost-effective approach for studying VWM. By combining TMS with EEG, RESTORE will surmount the limitations of previous work (e.g., the correlational nature of brain-imaging studies, the lack of evidence for neural activity in brain-stimulation studies) and thus result in causal evidence for the role of the sensory visual cortex during VWM. This scientific leap will not only resolve a longstanding controversy but also introduce an efficient approach for conducting neuroscientific research, hence contributing to the literature and advancing the current state-of-the-art. In addition, RESTORE will enhance the expertise repertoire of the researcher and the participating organisations. In turn, this will establish a strong foundation for pursuing ambitious and innovative research in the future, as well as provide knowledge and skills for training future researchers in contemporary research. RESTORE's innovative integration of TMS and EEG aims to decisively illuminate the longstanding debate about the role of the sensory
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The European network for power applications of superconductivity' (SCENET-POWER), addressing dissemination and exploitation.

assistant: **Impact**

The Thematic Network ENPAS (European Network for Power Applications of Superconductivity) aims at stimulating the development of demonstrators and prototypes of components and systems in the strategic field of power applications of superconductivity. It will be interconnected with and highly complementary to the Network of Excellence in superconductivity SCENET established by the ESPRIT-LTR programme on October 1st, 1996 for three-year duration. The latter, on the other hand, shall act in the field of electronic applications to set-up coherent strategies of research and development and create links between academia and industries. The main activities of ENPAS will include: the creation of S working groups each consisting of a small number of laboratories collaborating in pilot projects, the organisation of workshops for these pilot projects with relatively small numbers of participants, and the organisation of an advanced school on applications of superconductivity. ENPAS will also aim at establishing a common pool of scientific and technological knowledge for industries and academia through training of young advanced students and researchers.To get from the present state of the art to the proposed objectives, several actions will be implemented:1) Organisation of working groups to assess and define the specifications necessary for producing a demonstrator/prototype of:i) FCL's;ii) transmission cables;iii) magnets for MRI and energy storage;iv)motors. A fifth working group will assess the situation on superconducting materials from the novel ones to the production of wires and tapes. To discuss the current status of progress and the strategy plan for advancement in Europe, ENPAS will organise ten (2 per pilot project) meetings. Six-monthly reports will be produced. The
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Wearable interfaces for hAnd function recoverY' (WAY).

assistant: **Innovation**

This project addresses the scientific problem of recovery of hand function after amputation, or neurological disabilities like spinal cord injury, brachial plexus injury, and stroke. It introduces several conceptual novelties which explicitly take into account and overcome the limited band-width in actual Brain-Neural Communication Interfaces (BNCI). WAY demonstrators are able to restore a physiological bidirectional link between artificial aids and patients, and will be shown in clinical studies to improve the ability of users to perform activities of daily living (ADL) and thus to attain enhanced autonomy and quality of life. In other words, the project investigates new WAYs to link the brain with upper limb aids.This result is obtainable by employing already available sensorized hand assistive devices within the consortium--a dexterous prosthesis and an exoskeleton--and by developing non-invasive wearable interfaces designed for bidirectional data flow of sensory information and motor commands.The BNCI of WAY range in location, directionality, and working principles: efferent ones will implement biosignal processing exploiting machine learning for predicting user intentions (EEG, EOG, or EMG), while afferent ones will generate multi-modal stimulation patterns (vibro and electrotactile). The core of the system is the controller that dynamically processes sensor signals generated by the users and the device and drives efferent channels. The main novel feature is that the controller communicates with the user by means of temporally discrete signals that represent either commands or functional goal accomplishments and thereby mimics the high-level control in normal humans. The demonstrators will thus minimize the cognitive load of the users while providing necessary feed