RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Training network for next generation vaccinologists'.

assistant: **Objectives**

Vaccines are the most cost-effective health interventions available (WHO). The impact of vaccination on the health of the world’s population cannot be overstressed. Vaccinolgy is the multidisciplinary discipline of developing vaccine interventions it combines knowledge from basic sciences, medical sciences, public health and social sciences. Ideally a vaccinologists would be able to have a general overview of all disciplines involved but at the same time be able to zoom in on it’s own discipline.There is hardly any formal training to become a vaccinologist in the world and none such training exists at a PhD level in Europe. The need for a program to train vaccinologists is apparent and recognised . The vaccine industry is a largely European based industry. Investing in the future of this industry by training the next generation vaccinologists will boost European’s economy will provide high quality employment and will sustain European’s competitiveness. Clearly there are public health and economic reasons to invest in a training program training the European vaccinologists of the future.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Unique Method for a Neutron Electric Dipole Moment Search using a Pulsed Beam' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

My research encompasses the application of novel methods and strategies in the field of low energy particle physics. The goal of the presented program is to lead an independent and highly competitive experiment to search for a CP violating neutron electric dipole moment (nEDM), as well as for new exotic interactions using highly sensitive neutron and proton spin resonance techniques.The measurement of the nEDM is considered to be one of the most important fundamental physics experiments at low energy. It represents a promising route for finding new physics beyond the standard model (SM) and describes an important search for new sources of CP violation in order to understand the observed large baryon asymmetry in our universe. The main project will follow a novel concept based on my original idea, which plans to employ a pulsed neutron beam at high intensity instead of the established use of storable ultracold neutrons. This complementary and potentially ground-breaking method provides the possibility to distinguish between the signal due to a nEDM and previously limiting systematic effects, and should lead to an improved result compared to the present best nEDM beam experiment. The findings of these investigations will be of paramount importance and will form the cornerstone for the success of the full-scale experiment intended for the European Spallation Source. A second scientific question will be addressed by performing spin precession experiments searching for exotic short-range interactions and associated light bosons. This is a vivid field of research motivated by various extensions to the SM. The goal of these measurements, using neutrons and protons, is to search for additional interactions such new bosons mediate between ordinary particles.Both topics describe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Neural network computation for fast trajectory prediction' (Neural) targeting Seventh Framework.

assistant: **Abstract**

The Neural project proposes to take advantage of the neural networks capabilities to approximate the aircraft performance models in order to achieve the High Speed Numerical Integrator pursued by the MTM. The Neural development would allow SGO ITD to evaluate the potential benefit of the Neural Network for improving the access to the performance data.The Neural consortium was created to join the aeronautics and embedded experience of gtd and all the expertise in optimal control and high speed numerical integration with neural networks of the International Center for Numerical Methods in Engineering (CIMNE), a world-wide reference center in its area.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'EpiGrid: Soft and flexible high density electrode grids for epilepsy surgery' (EpiGrid) targeting Horizon Europe.

assistant: **Abstract**

Epilepsy is a highly prevalent brain disorder affecting 1% of the population. Brain surgery can cure epilepsy if we can delineate the diseased tissue intra-operatively. Unfortunately this delineation is currently not performed precisely and leads to poor success rates (50-70%). High frequency oscillations (HFOs) have been identified as a biomarker of epileptogenic tissues, which can be electrically recorded with intraoperative electrocorticography. These HFOs are specific of diseased epileptogenic brain tissues and remnance after an initial resection predicts continuation of seizures after surgery and thus may indicate incomplete removal. The problem is that currently available electrode grids do not provide an adequate recording resolution (too low electrode density). Moreover these electrodes are made of stiff materials, which yields low signal-to-noise level when recording from the cortical surface and which does not offer the possibility to record from within resection cavities, as the rigid electrodes cannot conform to the curvature of the cavity. We need high density flexible electrode grids that can adhere to the cortical surface and cavities. Neurosoft Bioelectronics produces flexible and high density electrode grids based on unique stretchable soft electrodes. Our goal is to use this grant to translate our clinical needs into an optimal design of soft electrode grids adapted for epilepsy surgery, with the help of  an industrial designer. We will first test these newly designed soft electrodes in vitro for clinical handability and improved signal quality, and eventually test them during epilepsy surgery in 12 patients. The recorded signals and clinical outcomes will be compared to those from standard rigid electrode grids. Improved delineation of the epileptogen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Pulse Oximeter Calibrator' (1994-1998).

assistant: **Concept**

The objective of the proposal is to contribute to a uniform quality of patient diagnosis during anaesthesia and in intensive care within the EC countries. The development of a convenient method and of the corresponding hardware for an objective comparison of commercially available pulse oximeters is a step in this direction. Conditions under which pulse oximeters are to be tested should not only refer to normal" patient values but also include pathological values because it is especially in these circumstances where the physician needs most the support of monitors such as pulse oximeters. Currently available pulse oximeters use different unpublished and often untested algorithms. This makes it difficult for the physician to validate his clinical findings in a reproducible manner. During the elaboration of the European standard for pulse oximeters (pr EN 865) this has been identified as a serious problem. The fulfilment of the essential requirements in the Medical Device Directive 93/42/EEC is not feasible without a calibration unit. This is the reason for CEN TC 215 to propose this problem for investigation in order to make a standardisation procedure possible. The project will be carried out in close collaboration with and under guidance of CEN TC 215. It will consist of two major steps: The first step includes the analysis of the optical properties of the tissue areas where pulse oximeters are applied and of the dynamic behaviour of pulse waves. Data from studies on a large population of patients will be stored in a data pool. In step 2, based on the data of step 1, a microcomputer controlled Calibrator will be developed by which different optical conditions of blood and tissue and of different pulse waveforms can be simulated. The Calibrator is to be tested in the la
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'A Middle Way? Probing Sufficiency through Meat and Milk in China' (MidWay).

assistant: **Innovation**

About one-fifth of the world's greenhouse gas emissions come from agriculture. Much of this relates to livestock used for animal-based foods. Rather than arguing for increased efficiency, MidWay probes the concept of sufficiency to explore its potential for reducing human impacts on Earth's biosphere while preserving overall welfare, i.e., its potential for defining a 'middle way' between 'too little' and 'too much'. To do this, MidWay studies the cases of meat and milk in China. While meat was always a high-status product, milk was historically considered a 'barbarian' food, and most Chinese were intolerant to it. Both products were scarcely consumed in Chinese history but have boomed in popularity over the past 40 years. While often thought about as a change of consumer preferences, it has taken a concerted effort by the Chinese government and domestic and international actors to make both products integral to Chinese food practices. Seeing China as a strategic research site to ask questions about the supply and demand of animal foods, the MidWay project hypothesises that what has made meat and milk integral to Chinese food practices might also be 'otherwise', i.e., opening up a possibility for a future disembedding of meat and milk from food practices. Thus, using a constructivist inspired lens, MidWay makes use of practice theory and 'systems of provision' to study the normalisation of animal foods in China, particularly since 1978, with China's opening up. The ultimate objective is to probe the concept of sufficiency as a useful organising principle to achieve reduced consumption - highlighted through the sub-objectives of understanding how meat and milk have been rendered desirable in China. Perspectives that show how food is connected to social, technical and cul
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Adaptable power density coating for energy efficient heating of cockpit and cabin' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The objective of HELI-COMFORT is to advance the technology readiness level of an innovative, purpose made, prototypic electrical heating system to a TRL 4 or higher level. After laboratory scale tests on smaller samples and an CFD based numerical simulation of such heating elements in a helicopter interior, this heating system will be integrated in an 1:1 helicopter mock-up and investigated under large laboratory environmental conditions in order to prove the ability to provide an adaptable power density coating for energy efficient heating of cockpit and cabin with reduced/eliminated need of bleed air from turbines.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Thin Si film based hybrid solar cells on low-cost substrates' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The ThinSi project will develop a solar cell processing chain for high throughput, cost-effective manufacturing of thin film silicon based solar cells on low-cost silicon substrates. The substrates will be made on the basis of an innovative powder-to-substrate concept. In line with the Workprogramme topic addressed, it will reduce the cost of solar cell modules compared to those made by the conventional wafer based approach. A set of innovative processes will be developed to realise the new low-cost concept and transfer the results into production. The new silicon based substrates will be made from low-cost material using state-of-the-art ceramics technologies. Cost effective processes for the formation of the thin film silicon base and the complete solar cell structure will be developed. New methods for optical confinement will be investigated. The electronic properties of individual solar cell materials and their interfaces as well as the relationship between the deposition parameters and the device properties will be analyzed using advanced characterisation and modelling. It will also develop a better understanding of relevant materials issues. Manufacturing procedures suitable for pilot scale production will be developed based on an innovative process chain. The produced solar cells will be assembled into complete modules. The project will develop innovative technologies and equipment prototypes that can easily be scaled up and transferred to production lines by the end of the project. New market opportunities for the SME and industrial partners will be created, both as production tool suppliers and as end-users of the technology.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Human Platelet Lysates-based Scaffolds for Interfacial Multi-tissue Repair' (InterLynk), addressing dissemination and exploitation.

assistant: **Impact**

InterLynk aims to develop multi-tissue 3D patient-specific scaffolds by providing a portfolio of highly compatible and biofunctional composite inks and biomaterials, and streamlining their co-processing using an upgraded AM equipment. Unprecedented biofunctionality in the synthetic reconstruction of complex interfacial tissues is expected to be obtained. A double network photocrosslinkable biomaterial system based on human plasma-derived Platelet Lysates (PL) will be used as base matrix. The PL-based hydrogels will be further combined with mechanically reinforcing biomaterials, namely CaP-based bioceramics and PCL-LA polymers, to produce bone-like and fibrous structures, respectively, and will be able to be blended with natural drug carriers (flavonoid-loaded nanomicelles). Compositional and structural variations will be enabled by combining photo-assisted printing and MEW/ESP in a single-step hybrid AM process. New computational tools will support the mechanobiological optimization of all biomaterials and final parts, as well as the AM process design. Superior biofunctionality of the InterLynk’ scaffolds will be validated in an highly complex multi-tissue interfacial biosystem, the temporomandibular joint. InterLynk will implement comprehensive strategies to engage key groups of stakeholders (clinical, engineering, regulatory and market-related) in the development of biological scaffolds, establishing a truly multidisciplinary co-creation process. These scaffolds are expected to have no counterpart in both fabrication and multi-tissue regeneration, avoiding time-consuming and costly procedures in both dimensions. This will increase current AM (bio)fabrication capabilities and application range, widely extending its use. Their high flexibility and unique performance wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'An Open Personalised Electronic Information Commerce System' (OPELIX).

assistant: **Innovation**

Professional users of information demand added-value services like personalisation, evaluation, categorisation and combination of multimedia information at the Internet. OPELIX aims at stimulating the appearance of a new type of information business on the Internet, which will offer the services requested. These new businesses will be provided with tools to create personalised information offerings, to deal with copyright issues, quality of service and with payment schemes that apply to this type of business.The OPELIX tools will be validated in two representative case studies. The most important development of OPELIX will be a language for describing business offers based on XML and its usage in an open information commerce scenario. The experience we gain with this language and the tools will be disseminated to the appropriate standardisation bodies. In addition, the results will be disseminated widely to the potential new SMEs at the InternetObjectives:Professional users of information demand added-value services like personalisation, evaluation, categorisation and combination of multimedia information at the Internet. Currently, there is no business model for this type of information commerce. The objective of the OPELIX project is to develop such a business model by providing tools to create personalised information offerings taking into account the copyright protection applying to that information, certification of the data, a timely delivery of the data, and with payment schemes that apply to this type of business.We will validate our business model on two pilot case studies of enhanced information commerce businesses. The business models and toolsets will be disseminated widely to interested SMEs and the business offer language will be proposed to standardisatio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Targeting long non-coding RNAs for novel treatment strategies in vascular diseases' in the context of a Horizon Europe call.

assistant: **Objectives**

The perception that RNAs are passive carriers of genetic information has been overturned. Due to the diverse targeting abilities and extensive research in RNA modification and delivery systems, nucleic acid-based therapies have emerged as suitable treatment options for many diseases. Targeting RNAs offers opportunities to modulate numerous cellular processes, including those linked to the large portion of ‘undruggable’ proteins. Currently approved protein-targeted therapies interact with <700 gene products, meaning that only 0.05% of the human genome is presently utilized for treatment. On the contrary, a large fraction of the human genome (>70%) is transcribed into non-coding RNAs. Humans produce more than 15.000 long non-coding RNAs (lncRNA), with a substantial subset of these likely being ‘druggable’ via RNA interference strategies, such as antisense oligonucleotides and siRNAs. In my current LongTx proposal, we aim at identifying suitable lncRNAs with relevance to vascular disease development and progression. To be successful, we made sure that we have identified suitable lncRNAs by profiling diseased human tissue from patients with carotid artery disease and stroke, as well as abdominal aortic aneurysms. Both diseases are currently being treated with suboptimal surgical interventions, and the growing affected patient population would tremendously benefit from novel treatment strategies that enable stabilization of advanced vulnerable atherosclerotic lesions, and also limit the risk for acute aortic ruptures and dissections. The two lncRNAs we have identified in preliminary studies using single-cell, bulk, and spatial transcriptomics are called CRNDE and NKILA. We propose to study these lncRNAs in disease-relevant preclinical in vitro (arteries-on-chips) and in vivo