RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'COMpetition between ion insertion and hydrogen evolution reactions in aqueous BATTery systems'.

assistant: **Concept**

Aqueous batteries (ABs) hold great potential for large-scale energy storage due to their safety and environmental compatibility. However, they face a fundamental challenge as the redox potential for ion insertion overlaps with the limit of the electrochemical stability window of water. This overlap leads to severe H2 evolution reactions (HER) in ABs, reducing cell efficiency and causing side reactions. Despite its importance, the underlying mechanisms of the competition between ion insertion and HER remain poorly understood. This project aims to address this challenge by combining the experienced researcher's expertise in batteries and X-ray techniques with the host institute's expertise in interfacial electrochemistry and electrocatalysis. We will develop a novel analytical platform, named X-Mass, designed to ensure compatibility between operando X-ray absorption spectroscopy and differential electrochemical mass spectrometry. Through the X-Mass, we will track the chemical composition of the active material and H2 gas production under consistent electrochemical conditions, allowing precise quantification of ion insertion (j-inst) and HER (j-HER) current densities. This will enable us to assess how both reactions vary and compete during battery operation. To further understand the factors governing their rates and limiting steps, we will explore the effects of electrolyte and electrode modifications on j-inst and j-HER. Electrolyte properties will be controlled by additional cations (Cs+, Mg2+, Al3+, etc.), insertion ion species (Li+, H+), and salt concentrations. Electrode properties will be modified using different polymorphs of the model materials, TiO2 and WO3. This approach will deepen our understanding of their reactions particularly in relation to the double laye
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Supramolecular Engineering of biologically iNSpired peptide nanostructurEs' (SENSE).

assistant: **Innovation**

To date, the main efforts for the design of bioactive self-assembled 1D nanostructures have been focused on the use of static assemblies. The development of synthetic systems with inherently stimuli-responsive behavior will open new possibilities for the creation of artificial architectures that mimic the natural protein nanostructures found in eukaryotic cells, which are dynamic, and capable of rapid growth or disassembly to tune their properties, and thus adapt to the cell needs. SENSE aims to:  1) Define robust peptide-based building blocks, and implement stimuli-responsive interactions between them to engineer complex self-assembled responsive nanostructures.  2) Modify these dynamic platforms to achieve precise nanoscale control over the presentation of bioactive molecules in the final multivalent nanostructures.  3) Apply these responsive and multivalent nanostructures as smart delivery vehicles and improved bioactive scaffolds. 4) Integrate them into living cells as artificial adaptor nanostructures that can present multiple signaling elements for controlling cell behavior. Taken together, the objectives of SENSE will define a new multidisciplinary approach combining organic, peptide, supramolecular and dynamic covalent chemistries, and nanotechnology for the development of adaptive materials that rely on dynamic interactions, and are therefore ideally suited to interfacing with living organisms. During my career I have acquired the singular background that combines chemistry, chemical biology, and nanotechnology required to achieve the objectives of SENSE. Particularly relevant to this project is my experience in peptide synthesis and their modification, as well as in the preparation of supramolecular peptide-based materials and the study of their properties in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Beyond classical conditioning:  Hippocampal circuits in higher-order memory processes' (HighMemory).

assistant: **Innovation**

Animals and humans adapt to changes in the environment through the encoding and storage of previous experiences. Although associative learning involving a reinforcer has been the major focus in the field of cognition, other forms of learning are gaining popularity as they are likely more relevant and frequent in human daily choices. Indeed, associations between non-reinforcing stimuli represent the most evolutionarily advanced way to increase the chances of predicting future events and adapting individuals behavior. Animals are also able to form these higher-order conditioning processes, but more research is needed to understand how the brain encode and store these complex cognitive processes.  In this project, I propose to study the role of hippocampo-cortical circuits in higher-order conditioning processes. These processes explain why subjects are often repulsed or attracted by stimuli, which do not have intrinsic repellent or appealing value and they were never explicitly paired with negative or positive outcomes. A proposed explanation of these ungrounded aversion or attraction is that these stimuli were incidentally associated with other cues directly reinforced, through a process called mediated learning (ML). However, with increased incidental associations, the subjects acquire more information, allowing them to separate the real saliences of the different stimuli. Therefore, ML evolves into reality testing(RT), a behavioral process that has been even less studied. These processes involve multiple brain regions and are characterized by accessible phases, making them perfect models to study the circuit-level regulation of complex behavior.   By using genetic, pharmacological, imaging and mouse behavioral approaches (sensory preconditioning), HighMemory proposes to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Augmented Reality GREEN_CAmera and Manufacturing' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

We will improve state of the art opto-electronic alignment processes with new low-power high-speed approaches, when adopted by the semiconductors industry will save 7.9 million tons CO2 emissions per year. Building the capacity to manufacture millions of cameras per year with minimal human intervention (solely to handle input trays with components and output trays with finished products), enabling high quality production in Europe at an extremely competitive cost.We will introduce novel biodegradable-packaging that when adopted by the semiconductors industry will replace 37.362 tons of plastic.Our current product replaces several components with a single device, the grant from this project will also replace the main camera of the smartphone, offering a dual-purpose universal camera module capturing full-sensor resolution 2D-images (13 and 48 Mpixels) and improved depth maps (1.4 and 5.3 Mpixels). Today’s AR cameras consume much higher power to generate low-resolution depth-maps (0.05 Mpixels) and require a second camera for 2D images. We will avoid 83.102 tons CO2 emissions per year.We will drastically improve competitiveness and provide Europe with a lead in a new market. With the “grant” financing this disruptive innovation will generate revenue of $13M in 2023, and $390M by 2025. The “equity” investment will scale-up world class manufacturing facilities for all our products to generate revenue of $1.98 billion by 2025 in a new high growth market. Studies by YOLE and Deutsche Bank size this market at $15 Billion for 2025.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Upgrading quality and competitiveness of fonio for improved livelihoods in West Africa' under Sixth Framework.

assistant: **Concept**

This project aims at increasing the value of fonio. We will provide stakeholders and local decision makers with information on the potentialities of this tiny grain. We will also work out, with them, suitable and sustainable solutions to increase the sup ply of high quality processed products for local and niche export markets.As scientific and technical data concerning this under-utilized tropical cereal are scarce and very often incomplete, we will first acquire an in-depth knowledge about fonio. Namel y, we will focus on its biochemical composition and its technological, cooking and nutritional qualities. We will identify the ecotypes with the best agronomic, technological and commercial potential. By developing adapted processes, we will work to impr ove quality of the local product and to make new products. This should be done so as to enhance regional trade and to stimulate exports of both good quality white fonio and high added value new products . Concurrently, we will study the conditions for im proving the competitiveness of the local commodity chain so that fonio can become a source of production diversification and higher incomes for local farmers and processors. We will also evaluate the effects of developing an export market chain on the ev olution of the local commodity chainWe will promote a multidisciplinary approach involving scientists from various backgrounds: food technology, nutrition, process engineering, mechanization, social sciences, agronomy, ... and we will support research/d evelopment actions with a participatory approach involving producers, processors, women's groups and small enterprises that will benefit directly and quickly from the research results. The project will issue practical recommendations (technical, strategi c and organisati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'advanced Muon Campus in US and Europe contribution', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

aMUSE plans to strengthen and extend the collaboration between EU and US researchers to carry out cutting-edge searches for New Physics (NP) in the muon sector, while promoting the development of next generation muon accelerators. The project finds its roots in the previous MUSE network based at the Muon Campus of FNAL, USA. Here, the Muon (g-2) experiment aims to solve the long-standing muon anomaly puzzle and related NP implications collecting a twenty-fold increase in statistics compared to its predecessor. A high-profile discovery path for the search of charged Lepton Flavour Violation (cLFV) will be exploited by the Mu2e experiment, whose goal is to improve the discover sensitivity for the as yet unseen muon-to-electron conversion by four orders of magnitude, reaching mass scales of 10^4 TeV/c^2. aMUSE promotes an ambitious extension of the Muon Campus activities. Its R&D programs will exploit the future phase of Mu2e-II with an upgraded proton beam providing a ten-fold increase in muon yield. aMUSE aims to design and develop state-of-the-art detectors to face this challenge. At this high intensity frontier, aMUSE will explore the design of a beam line extension to seed the birth of new generation experiments searching for cLFV muon decays as a possible alternate running to Mu2e-II. Its final goal is to vastly improve sensitivity with respect to currently existing or proposed facilities and promote the integration of EU groups in developing accelerator and detector strategies. aMUSE further provides an excellent platform for an ambitious EU-US network to  advance the development of muon beams. Low and high energy research is synergistic: muon cooling is fundamental to both high-energy muon collisions and low-energy high-intensity muon beams. The US longstanding com
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Mechanism of Chromatin Replication' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Each time a human cell divides, it must make an exact copy of its 46 chromosomes. This requires precise duplication of ~6 billion base pairs of genomic DNA and all its associated proteins.  Mistakes in this process can lead to developmental defects and cancer.  Chromatin is packaged as nucleosomes comprising 147bp of DNA wrapped around a core of eight histone proteins.  The nucleosome is a stable structure which must be disrupted each time the double helix is accessed during replication. ‘Epigenetic’ information in the form of covalent histone modifications must be re-established on both daughter strands immediately behind the replication fork. Inheritance of parental histones with their covalent marks must be coordinated with deposition of new histones into nucleosomes.  And repressive heterochromatin must be replicated and immediately re-established after replication.   Our goal is to achieve a deep understanding of how DNA replication is coordinated with the disassembly and reassembly of chromatin to ensure accurate chromosome duplication. We will use in vitro reconstitution of chromatin replication along with molecular genetics and structural biology to:•Generate a molecular view of how the budding yeast replication machinery, with other key factors, disrupts parental nucleosomes during replication.  •Determine how parental nucleosomes are transferred to the nascent daughter strands.  •Understand how deposition of new histones is coordinated with the inheritance of parental histones.  •Characterise how budding yeast heterochromatin is disrupted and re-established during replication.  •Begin studying this process using human proteins, focussing on areas where human replication mechanisms diverge from yeast.  This work will underpin our long-term goal of reconstitutin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Inside/Out: using storytelling to understand the politics of exclusion in Europe and South Africa' (Stories), addressing dissemination and exploitation.

assistant: **Impact**

Contemporary political narratives in the UK and South Africa are explicitly orientated around ideas about who does, and does not, belong. The UK and South Africa, while different, share trends towards inequality and the othering of migrants as responsible for social problems. Both inside and outside groups express a powerful sense of alienation and hopelessness. This fellowship will use storytelling to generate new bottom-up narratives to challenge dominant top down discursive politics of exclusion. Personal stories will be created by research with people from different communities that are typically positioned as being against one another. These creative, story-based research methods will catalyse public dialogues on the possibilities for new, more inclusive political narratives to build understanding and trust between groups. The fellowship will enable the researcher to strengthen the interdisciplinary basis of her research, by bringing together the disciplines of politics, sociology and psychology. She will also learn from the expertise and networks of Professor Heaven Crawley and colleagues at the Centre for Trust, Peace and Social Relations (CTPSR) at Coventry University working on public and political migration narratives in the UK and Europe. This will lead to future research collaborations and career development opportunities at CTPSR. CTPSR will, in turn, benefit from the researcher’s in-depth expertise in the use of storytelling to build dialogue between communities and her knowledge of the ways in which narratives of migration, inclusion and exclusion have developed in South Africa and from her experience globally.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Planning Regional-Scale Multimodal Operations for Innovative Air Mobility Services' (PRIAM).

assistant: **Innovation**

PRIAM’s vision is that, within the next decade, regional-scale IAM services will be part of the European MaaS ecosystem, helping address regional connectivity challenges. Decisions on IAM will be supported by digital twins, powered by mobility data spaces and AI tools. IAM services will create sustainable value for aviation, while improving passenger experience, boosting capacity, enhancing efficiency and minimising environmental impacts. The general objective of PRIAM is to develop a data analytics and modelling toolset that supports a passenger-centric integration of IAM into multimodal regional transport networks across Europe. The PRIAM Solution will help understand passenger needs for regional travel, anticipate IAM adoption and use patterns, plan resilient IAM infrastructure networks that are seamlessly connected with other transport modes and optimise IAM service performance taking advantage of multimodal data sharing and passenger information systems. The specific objectives of PRIAM are (i) define an impact assessment framework for regional IAM services that evaluates how different IAM vehicular concepts and business models address regional connectivity challenges and passenger needs; (ii) develop and validate a concept outline for PRIAM, consisting in a data analytics and modelling SESAR Solution for planning the integration of IAM infrastructure and services into regional multimodal transport networks; (iii) evaluate the capabilities of PRIAM through a set of case studies in European regions that show how the PRIAM Solution can help IAM regional-scale services improve passenger experience, capacity, environmental sustainability, and operational and cost efficiency; and (iv) derive a set of recommendations for the implementation of regional IAM services, based
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Evolution of gene regulatory networks in animal development' under Seventh Framework.

assistant: **Concept**

Genetic and mutant analyses in Drosophila and other standard model organisms have revealed hierarchical gene networks and identified some key regulatory genes acting in animal development. While surprising conservation exists on a broad scale between distant phyla, significant differences have also been detected. Systems biology approaches in the main model systems have now revealed more complex gene regulatory networks (GRNs). To understand the logics and evolution of GRNs more basal animal phyla need to be studied. The comparative analysis of GRNs has thus become a new major focus of systems biology. The key questions are: (1) Does the higher complexity of some species correlate with an increase in complexity in GRNs? (2) How do GRNs evolve to drive changes in body plans? The major challenge for the next generation of researchers will be to integrate knowledge of developmental biology, bioinformatics, functional genomics and evolutionary biology. This requires a new combination of interdisciplinary training to bridge the gap between what are currently quite separate disciplines.  In this ITN we will gather and compare information on GRNs from diverse animal systems, representing all major animal lineages, with particular emphases on the mesoderm specification network and the head regionalization network. To this end, we will provide early researchers with the skills necessary to apply state of the art systems biology, genomics and bioinformatics tools to emerging model organisms. The early researchers will receive an in-depth introduction into the selected model systems and training in how to conduct and analyze genomic experiments by the members of this ITN, which includes a company specialized in array technology. We will organize  joint ITN/EMBO training courses an