RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Towards a new era of representative democracy - Activating European citizens’ trust in times of crises and polarization'.

assistant: **Objectives**

How can we conceptualize and empirically measure political trust and legitimacy beyond the usual survey question “How much trust do you have in the parliament?”? Does the multi-level nature of European representative democracies require an identical level of citizen support at the regional, national and EU levels? How does social polarization on key policy issues of our times –immigration, climate change, and gender inequality– challenge the political trust in, and legitimacy of, democratic political systems? And what can policymakers and civil society do to master these challenges? ActEU aims at finding answers to these questions pursuing two overarching goals: In phase 1, we map and investigate persistent problems of declining trust, legitimacy and representation in Europe with a particular attention to the polarization of societies and the EU’s multi-level structures. Providing an innovative conceptual framework on political attitudes, behavior and representation across Europe, we establish an original empirical infrastructure based on an innovative combination of methods and newly collected quantitative and qualitative empirical data (focus groups, experimental surveys, web scraping). In phase 2, these results will flow directly into the creation of a toolbox of remedial actions to enhance political trust in and legitimacy of European representative democracies. In cooperation with a newly created Civil Society Network, Youth Democracy Labs across 13 European cities and in exchange with political cartoonists “Cartooning for democracy”, we will develop context-sensitive solutions for all polity levels and some of the most polarizing policy areas, and craft tailor-made toolkits for both policymakers and civil society and the educational sector. Finally, we deploy a di
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Viral Haemorrhagic Fever: Modern Approaches for developing bedside Rapid Diagnostics' (VHFMoDRAD) under Horizon 2020.

assistant: **Objectives**

VHFMoDRAD will develop and deliver rapid and point-of-care singel/multiplex diagnostic tool(s) that will significantly increase our capacity to handle outbreaks with Filoviruses and other viral hemorrhagic fever diseases in Africa. The overall aim of VHFMoDRAD is to carry on the outcome of the currently running EbolaMoDRAD project to the next level, which is behind of the scope of that project.The goals of VHFMoDRAD will be done via a multidisciplinary research consortium drawn from key European and African research organisations and also industry and SMEs, thus consolidating previous tools and knowledge. VHFMoDRAD will also put in place a strong capacity building programme in West Africa The project will disseminate widely all results as they become available, notably to public health bodies and non-governmental organisations (NGOs), via a strong outreach programme. To achieve this overall aim an intensive work plan will be put in place, with the following specific objectives:- to develop rapid molecular and serological single/multiplex detection methods;- perform preclinical validation of diagnostic tools;- to validate the successful diagnosis tools under field conditions; - implement a strong capacity building programme in West Africa by a twining program;- to exploit results;- to disseminate the results to public health bodies, NGOs, outbreak management teams and local hospitals in West Africa.


**Keywords:** VHF, RPA, LFA, POCT, rapid early detection, Multiplex, Ebola, twinning, capacity building, validation, NHP
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'MOdular Spacecraft Assembly and Reconfiguration' (MOSAR).

assistant: **Innovation**

Since commercial exploitation of satellites was endeavored more than 50 years ago (Telstar 1 in 1962), commercial use of space became a huge and very much strategic market, reaching ~50 billion of USD in 2004, and in the range of 256 billion of USD in 2013 (OECD global estimates, 2014).Fierce competition is to be expected in the worldwide space industry to obtain major shares of the key commercial space segments.Offering cost effective, performant, reliable, scalable and flexible solutions will be essential to make the European space industry spearheading strategic segments of the commercial space. The development of novel, European technologies that would allow standardizing satellites components, facilitating their assembly, reducing time between customer’s orders and commissioning in space, repairing and upgrading components directly in orbit instead of replacing entirely a deprecated or damaged satellite, would provide extremely valuable competitive assets to establish European leadership in a number of key commercial space segments. Leveraging the outcomes of the Space Robotics Technologies SRC building blocks (from Call 1 / OG1,2,3,4,5), this proposal (MOSAR) aims to develop, integrate and demonstrate such technologies required to enable a fundamental shift of paradigm with satellites (and more widely spacecrafts) manufacturing and commercial space exploitation.As a key driver, MOSAR intends to leverage know-how and standards already available in the European space industry for satellites  (small / nano sats in particular), to facilitate the uptake of project results by future customers. Key representatives of that industry are part of the consortium.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'PREPARATION AND LAUNCH OF A LARGE-SCALE ACTION FOR QUALITY TRANSLATION TECHNOLOGY' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The support action will prepare the grounds for a new type of collaborative MT research dedicated to overcoming existing quality barriers. QTLaunchPad will assemble and provide needed data and tools in-cluding specialised translation corpora, test suites and tools for quality assessment, create a shared quality metrics for human and machine translation, improve automatic translation quality estimation, extend an existing platform for resource-sharing to the needs of quality MT research, define strategies and challenges and then plan and launch a large-scale research and innovation action for a breakthrough in quality translation technology.<br/>European research has the potential to overtake Google in the pursuit of automatic quality translation! A successful venture directed at breaking the quality barriers in MT and putting European MT research ahead of its competitors requires a strong combination of expertise, scope and ambition together with the courage to diverge from mainstream research in goals and style. The envisaged progress will be based on highly specialized quality services, an analytical systematic fight against quality obstacles, improved utili-zation of shared data and tools, the integration of translation providers in research, deployment, testing and business models, and a concerted competitive model of technology evolution. In contrast to the large generic gist translation online services, the final target will be a service model based on competition and combination of specialised services, accounting for and capitalising on the SME-dominated European LT and LSP industries. For the planning process, QTLaunchPad will assemble the best European centres of MT research, the most sophisticated and enthusiastic large-scale users of translation technology i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'NeW LONG FIBRE REINFORCED THERMOFORMED SHEET PRODUCTS USING RECYCLED MATERIALS, AND A TOTAL SYSTEMS APPROACH' (1994-1998) under Fourth Framework.

assistant: **Objectives**

The plastics industry in Europe is experiencing strong pressures to recycle materials for reuse. In particular the packaging industry has a 20% recycle target by the year 2000. Present recycle volumes are well short of this figure in European countries with the exception of Germany where recycling legislation has been in force for some time. Besides collection and washing, two specific problems inhibiting efficient re-use of thermoplastic polymers are (1) Sorting into polymer type, and (2) Loss of properties in the recycle process. The objective of the present project is to reduce or bypass these two problems by harnessing new fibre composite and blending technologies to the recycle objective. While the project will be specifically aimed at novel thermoformable sheet products, which is the market the two proposers serve, it is expected that the technology will be applicable to other product forms serving the automotive, leisure, packaging, domestic and engineering sectors. The project will explore the use of new long-fibre composite and blend technology which is being developed by the RTD perforrners. This holds promise of giving cost effective improvement of strength and stiffness largely independently of the specific grade or type of polymer thus relieving both problems (1) and (2). While the project will establish the technological platform for these ideas, work will be required subsequently by all the eventual participants to turn them into actual marketable products. The project will therefore also establish the ground rules for successful product design using the new materials. This will be done by considering the total system of market requirements, manufacturing economics and recyclate sources. /The plastics industry in Europe is experiencing strong pressures to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'A multimodal approach to accelerate drug discovery and development in Alzheimer’s disease' (MAP-AD) targeting Horizon 2020.

assistant: **Abstract**

Alzheimer’s disease (AD) is a major societal challenge, impacting up to one third of the population over 85 years old. The European Commission and various international bodies have repeatedly fostered research initiatives to prevent the development or stem the progression of the disease. Several recent phase 3 clinical trials have failed to show any efficacy in slowing disease progression, calling into question the current drug targets. This project will use genetic data to identify new AD-relevant molecular pathways and their associated drug targets. Given the increased risk of AD in women, we will apply our innovative analyses not only to autosomal variants but also to X-chromosome variants as well. The mechanistic effects of genetic variants on pathogenesis will be delineated using gene expression from post-mortem brain tissue and AD biomarkers derived from multimodal brain imaging studies. These in-vivo PET and MRI biomarkers are essential for enrolling patients correctly in clinical trials and assessing the effect of treatments on disease progression. We will assess whether a polygenic risk score, based on thousands of genetic variants, will be useful in predicting an individual’s clinical and biomarker progression over time. This project is markedly interdisciplinary in nature between its analysis of multimodal brain imaging and genomics data, and the combination of big data analysis guided by expert medical knowledge of the pathogenesis. Results have the potential to (i) identify new drug targets and (ii) strengthen clinical trial design, thereby speeding the development of drugs for the prevention and treatment of AD. This fellowship represents a unique opportunity to transfer knowledge and analysis methods of next generation genomics AD data from one of the lea
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Lattice Boltzmann For Advanced SimulaTions'.

assistant: **Objectives**

The intricate dynamics of fluid interfaces, disordered liquid-liquid emulsions, and soft microfluidic droplet crystals, collectively knownas soft glass materials (SGM), pose challenges to non-equilibrium thermodynamics and hold profound implications for engineeringapplications such as combustion, materials design, and food processing. Advances in SGM modeling within the ERC COPMAT projectoffer opportunities for innovative mesoscale materials in fields like tissue engineering, photonics, and catalysis.The Lightweight Lattice Boltzmann (LB) scheme, which relies on hydrodynamic moments, models SGM by preventing dropletcoalescence including near-contact interactions (NCI) due to surfactants. Integrated into LBcuda, an open-source software optimizedfor GPUs, it efficiently simulates complex flows while saving electrical energy, in line with the goals of the European Green Deal.The LBFAST project aims to optimize LBcuda's implementation for HPC clusters powered by GPUs, achieving processing rates ofseveral hundred GLUPS while using only 50% of computational resources, resulting in a 75% reduction in energy costs compared tostandard LB methods. This enhancement enables accelerated production rates for industrial applications and aligns with the criteriaof the EuroHPC Joint Undertaking, benefiting users addressing energy and environmental challenges in the next exascale computinggeneration.


**Keywords:** Computational Fluid dynamics, Lattice Boltzmann method, High performance computing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Biodegradable fluorescent nanoprobes for early detection of (pre)malignant lesions of the gastrointestinal tract' (THERAPROBES), addressing dissemination and exploitation.

assistant: **Impact**

Accurate diagnosis of (pre)malignant gastrointestinal (GI)-tract lesions is critical for patient survival. Early detection of asymptomatic disease of the GItract improves the chance of curative intervention by 50−80% as compared to poor five-year survival rates for symptomatic advanced malignant disease. Regular endoscopic surveillance in high-risk patients misses 25% of (pre)malignant lesions – the most clinically relevant marker for malignant progression. This clinically significant miss rate is due to the subtle appearance of such lesions under white-light endoscopy and sampling errors inherent to a random-biopsy surveillance paradigm, which increases inter-operator variability and compromises diagnostic accuracy. Even when malignant disease is detected, lack of sensitive contrast agents compromises delineation of the true extent of the lesion. These factors decrease the physician’s ability to achieve successful therapeutic intervention through resection or ablation. About 33% of GI-tract lesions progress or recur at or near the therapeutic site, commonly requiring aggressive yet often non-curative, systemic treatments negatively impacting the patients’ quality of life. There is an unmet clinical need for endoscopic optical imaging approaches that reliably detect those lesions with high sensitivity and specificity. To develop a clinically viable strategy, I propose to use biodegradable, fluorescent silica nanoprobes (FSN) that provide real-time visualization of the lesions over a range of scales during routine endoscopy. Since FSNs accumulate at the tumor sites solely due to their size and increased vascular permeability, no active targeting is needed, making these imaging agents ubiquitously applicable. Endoscopy augmented with FSNs has tremendous potential for bett
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'SCience, Innovation, FIrms and markets in a GLObalized World' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

In 2000, EU leaders committed to the objective of making Europe ‘the most dynamic and competitive knowledge-based economy in the world, capable of sustainable economic growth, with more and better jobs, greater social cohesion and respect for the environment.’ They drew up the ‘Lisbon agenda’ to achieve this goal by 2010. The central strategy was based on policies to encourage investment in knowledge. Knowledge as a public good with potential spillovers is the rationale behind intellectual property protection and subsidies for investments in innovations that will potentially lead to high spillovers. University research that creates basic knowledge is a leading example of this. But research shows that spillovers are also generated from private firms’ R&D and that firms can therefore benefit from the presence of more innovative and more productive firms. But which universities and which firms are more innovative? And how does globalization influence the answer to these questions? Finally, how can policy influence the innovation process? This project aims at answering these questions, without forgetting their implications in terms of income inequality and volatility, which impacts on the political sustainability of the innovation dynamics.To do this, the first part of the project will focus more specifically on the knowledge sector itself. This second part of the project will look at the ‘bigger picture’, looking at the overall organization of firms in the global knowledge economy, as well as its implications on markets and inequality. The third part will contain a summary and policy recommendations: while the project brings together researchers at the frontier of academic knowledge on these topics, its outcomes will be highly policy-relevant. We plan to end the project wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Epigenetic Regulation in Acinetobacter baumannii'.

assistant: **Objectives**

Gene expression in bacteria is regulated by a multitude of mechanisms to facilitate adaptation to changing environmental conditions and during infection, which is key to their evolutionary success. To ensure that genes are only expressed in the right place and at the right time, access of transcription factors to promoters that drive gene expression can be controlled by DNA binding proteins and DNA methylation. DNA methylation is a seemingly simple, yet powerful mechanism mediated by methyltransferases (MTases) of restriction-modification (R-M) systems or orphan MTases which methylate specific genomic sites and can modulate transcription factor binding thereby regulating gene expression. Although epigenetic regulation is widespread in bacteria, the exact regulatory mechanisms are often unknown. Epigenetic regulation is often found in pathogenic bacteria and it was shown that methylation can affect their virulence, biofilm formation and other important features. In this project, we will use the WHO priority pathogen Acinetobacter baumannii as a model to decipher epigenetic regulation. A. baumannii strains encode from one to ten different MTases and it was shown that the deletion of the most conserved A. baumannii MTase decreased motility and virulence  suggesting a gene regulatory role for this MTase. This project will investigate the impact of MTases on epigenetic gene regulation of A. baumannii using bioinformatics and functional genomic approaches to uncover their role for A. baumannii biology. Considering regulatory MTases as a potential drug target, understanding epigenetics would inform new approaches for the treatment of A. baumannii infections. Additionally, the distribution of R-M system genes in different strains of bacteria can be useful in phage therapy devel