RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Visual Data Mining System' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

The aim of VITAMIN S project is to go beyond products and experience gained through involvement in other projects by designing an interactive environment for graphical data analysis, that offers innovative visualization and enhanced graphical data analysis methods, useful for users, statistician or not. Indeed, visual inspection can be considered the basic step of exploratory data analysis process.Using directly the obtained results as input for more complex numerical analysis, they allow a considerable reduction of such method computational cost. The system will provide linking between visualization methods where possible, so that the full potential of several visualization methods is used at the same time by the user during the analysis process.Objectives:The objectives of VITAMIN S are:1. Enhancement of classical graphical data analysis methods by incorporating dynamic and interactive techniques;2. Implementation of innovative visualisation methods;3. Some possible fields for methodological developments can be related to: NSI's typical data such as: Structured Data both at disaggregated and aggregated level, Time Series, and Spatial Data;4. Integration of the implemented graphical and visualisation methods into a unique and homogeneous environment for a genuine Visual daTA MINing System (VITAMIN-S) by:- offering classical and innovative visualisation tools;- providing an interactive framework to explore multivariate data;- linking displays, so that the full potential of several visualisation methods can be used at the same time during the analysis process;- providing interactive reports that trace the data exploration steps.Work description:The fulfilment of the project objectives requires under the two phases the following actions:Phase A:- Identification of the nee
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Modification of cell functions by human cytomegalovirus proteins in the absence of viral genome expression - role of incoming viral phosphoproteins 65 - ul83) and 71 - ul82' (1994-1998).

assistant: **Concept**

Research objectives and content Infection with human Cytomegalovirus (HCMV) leads to profound, prolonged immuno-suppression which cannot be explained by lytic infection of immunocompetent cells. Results obtained in the host laboratory demonstrate that virion proteins can affect host cell metabolism and led to the hypothesis that incoming viral proteins may modify immune competent cell functions. The significance of incoming viral protein, pp65, both in vivo and in vitro, makes it important to define cellular proteins with which pp65 interacts in order to establish the role this protein plays in observed host-cell modifications. The transcriptional dependence of structural protein pp71 on pp65 synthesis requires investigating physical and biochemical interactions of these related phosphoproteins. We will develop expression vectors for both proteins with a tag epitope to allow (1) controlling the fate of tagged versus endogenous proteins produced during infection (2) performing co-precipitation experiments in uninfected cells transfected with recombinant expression vectors to determine normal cell proteins with which the viral proteins interact and (3) investigate biochemical modifications attributable to these proteins. Knowledge acquired and material developed should (1) help understand how HCMV modifies the functioning of immunocompetent cells in the absence of viral genome expression, (2) define functional interactions of viral pp65 and pp71with host-cell proteins and thus (3) might provide new targets for the intervention with antiviral drugs. Training content (objective, benefit and expected impact) Objective: to improve knowledge in virology and molecular biology of human cytomegalovirus (HCMV). Benefit: To specifically learn about the manipulation of eukariotic ce
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Integrated porous cementitious Nanocomposites in non-Residential building envelopes for Green active/passive energy STORAGE' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The NRG-STORAGE project will launch a novel breakthrough solution that replaces the currently available insulation materials used in building envelopes, by proposing a multi-functional and eNeRGy saving cementitious Foam (NRG-Foam). The heat-activated foam will be used for passive/active management of energy transfer and will be applied to new building envelopes and to retrofit existing ones. Graphene-based nano-additives will be doped in both cementitious foam matrix and bio-based PCM fraction for improving the thermal storage capacity, volume stability and mechanical properties of the resulting composite. Two active/passive systems will be prototyped and validated. First, an implicit heating system for thermal activation of the added nano-graphene will be installed representing a material-based approach, and, second, a multi-functional energy efficient façade system (MeeFS) will be installed, to diverse and direct the thermal absorption capacity and shadowing of the external building walls for optimizing the NRG-Foam’s. NRG-Foam composites will be optimized to achieve the best compromise between thermal insulating properties (air bubbles) and heat storage capacity (bio-PCMs). A highly conductive cementitious paste will be designed and produced,  targeting on an increase in thermal conductivity (once activated up to 10 times for bio-PCM, and 2 times for cement matrix), and an enhanced efficiency of bio-PCM heat storing performance (> 5 times). With this project, the partners will develop an innovative functional material that combines high insulation capabilities (more than 25% of classical layers) and high energy-storage capacity (more than 10% of improvement in active applications). Furthermore, the NRG-Foam layer will be characterized by a high water and air tightne
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Electron and positron induced chemistry'.

assistant: **Objectives**

Electron and positron induced reactions in both the gaseous and condensed phases initiate and drive, through Selective molecular bond breaking patterns, the basic physico-chemical processes in many different areas of Science and technology from industrial plasmas to living tissues. The study of electron induced chemistry in all Phases of matter therefore requires a comprehensive understanding of the dynamics of electron-molecule Reactions if there is to be continued progress in these diverse areas of science and technology. In comparison the field of positron induced chemistry is still in its infancy with the development of new laboratory sources and theoretical modelling only now suggest exciting possibilities for a whole new field of antimatter chemistry. Europe is at the forefront of world research in the study of electron and positron induced chemistry In this Network leading members of the European Research community will Collaborate in an authoritative Investigation of electron and positron induced chemistry in three discrete phases of matter gaseous; clusters and In particular the Network will use state-of-the-art experimental and theoretical techniques to;1. Study fundamental electron and positron energy transfer processes2. Study electron and positron impact dissociation processes yielding reactive neutral, anion and cation species3. Study how such processes are modified in the different phases of matter (gases, clusters and on surfaces)4. Probe new reaction processes initiated in denser phases of matter (e.g. nucleophilic substitution)5. Train a new generation of younger scientists in the skills and techniques required to further develop this areaThree different molecular compounds have been selected to illustrate these processes; halogenated hydrocarbons And
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Determining the masses of low mass X-ray binaries in our Galaxy' (2002-2006).

assistant: **Innovation**

Low mass X-ray binaries are two gravitationally bound stars, where the secondary is a normal solar type like star and the primary a compact object, i.e. a black hole or neutron star. These systems are excellent laboratories to test several theories, includ ing stellar evolution, theory of accretion and the theory of relativity. However, accurate measurements of the masses of the two components in these binaries are necessary to test these theories, and that has been complicated since the secondary is many magnitudes fainter than the accretion disk around the compact object. We propose a new technique to measure the masses more accurately than has been possible thus far. Recent observations have shown that a signature of the secondary is present in certain fluorescence lines, in particular the Bowen fluorescence lines around 4640 angstroms. Furthermore, the observed optical emission is mainly due to reprocessing of the X-rays, and any variability observed in the X-rays should also be present in the optical , but delayed with a few seconds depending on the reprocessing time and distance of the optical site compared to that of the X-rays. Simultaneous X-ray and high temperal, high resolution optical spectroscopic observations, should be able to measure the de lay in the fluorescence lines, and thereby constrain the system parameters of low mass X-ray binaries. For these observations large, 10 m class, telescopes with spectrographs that have high timing capabilities are necessary, and those will only become avai lable by the end of 2005 when GranteCan and SALT come on-line.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Low cost high speed soil disinfestation system to replace methyl bromide (SOILPREP)' (SOILPREP) targeting Sixth Framework.

assistant: **Abstract**

With increasing EU population density leading to further projected increases in the intensity of horticultural cropping by 2% pa, and the phasing out of Methyl Bromide with no chemical alternative available, there is an urgent need to provide horticultur alists with an environmentally friendly, safe, cost effective disinfestation method for their land Our idea is to develop a high-speed treatment system based on a synergistic combination of injecting steam under pressure into the soil, a vacuum recircula tion system and mixing of the particles to achieve rapid equilibration and low losses at high input rates. In addition our idea efficiently generates the required steam directly from the soil moisture over a novel solid state heat exchanger, removing the need for costly and cumbersome large boilers and water transportation bowsers which limit the speed of application and damage the soil. The heat penetration rate from this technique will be high enough to mount the unit on a standard soil preparation rig, removing the need for slow and costly separate disinfection pass over the ground, bringing down operating and capital costs to affordable levels. The SME partners constitute a supply chain partnership that includes a heat source and control systems  manufacturer, a spray and injector manufacturer, a soil preparation equipment manufacturer, a control systems manufacturer, together with a systems integrator and service provider in the soil turning and granulation area. End user input is also provided from a farming co-operative group and the technology developer who invented this concept. By helping leverage the limited RTD resource of the SME's this project will allow them to afford to produce a truly innovative product and disseminate it to develo p a new application m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Cost Efficient Recycling of Elastomeric Materials With Noise and Vibration Damping Applications' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

The European Industry has a strong need for: 1. low cost elastomers in order to increase the competitivity of traditional sectors such as shoes industry or technical rubber or polyurethame goods production (mats, seats, solid tyres...) 2. Iow cost noise and vibration damping elastomeric composites for improvemenl of transporl means quality (aircrafts, cars, railway vehicles), improvement of industrial working environment and buildings noise insulation. At the same time, a sharp social and environmental issue arises from elastomer waste. European rubber and polyurethanes waste represents about 2 millions tons of scrap materials per year. Wilhin this conlext, lhe objeclive of this projecl is lo develop complele recycling processes for rubber and polyurethane waste aimed at the mass production of low cost elastomeric composites with noise and vibration damping properties. These recycling routes will be based on the manufacturing of polymeric composite materials containing a large volume fraction of powderized elastomeric wastes. This project will focus on specifications on final recycled composiles, optimization of crushing and separation processes, development of a wide set of innovative polymeric materials, small scale production of prototype finished products and environmental impacts analysis. Main innovation will consist in systematic tailoring of the recycled composite materials for each aimed application. Size, chemical nature, volume fraction of granulates and malrixes will be chosen in order to achieve finished products with valuable functional properties in terms of mechanical cohesion, noise absorption and vibration damping, friction coefficient and heat insulation. Moreover, recycling of cross linked elastomer powders requires the creation of chemical bondings
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Genetically engineered microorganisms as whole-cell biocatalysts' (1998-2002).

assistant: **Innovation**

The Training Site Genetically Engineered Microorganisms as Whole-cell Biocatalysts" is located at Vienna University of Technology and consists of five research groups with expertise in applied biocatalysis, natural product synthesis, genetic engineering, fermentation technology, and analytical chemistry. It is the aim of GEMCAT to provide an opportunity to learn latest developments in the design and application of recombinant organisms in biotransformation. It is our objective to offer an approach to this area of research from various educational starting points. By bringing together experts from several key disciplines a unique insight into the many different aspects of biocatalyis and biocatalytic processes is provided to the fellows. The Training Site specifically addresses candidates from one of the key areas who are interested in expanding their knowledge and expertise into all other fields relevant to biocatalysis. The experimental projects offered to the fellows are strongly linked to ongoing research activities in the groups involved and will contain development of genetically engineered whole-cell systems, investigation of recombinant organisms as biocatalysts in preparative chemistry, and application of microbial biotransformation in the synthesis of biologically active compounds. Additionally courses on principles and application of biocatalysis, special methods in gene expression, aspects of fermentation technology, and structural elucidation are offered by experts of the site. Team oriented candidates for fellowships should have a solid background in one of the key disciplines (organic chemistry, microbiology, or fermentation technology) and look for experimental challenges in an interdisciplinary field of research."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'HeartRater: Tools for the systematic evaluation of interoceptive ability' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The Proof-of-Concept grant seeks to develop a commercializable platform to quantify how sensitive individuals are to their own heartbeats.  This platform will have applications in clinical psychology, personalized medicine and beyond.We each differ in the way we express or control our emotions, in the way we base our decisions on feelings, and react to stress or excitement.  A key determinant of these aspects on our behaviour is our sensitivity to changes in the emotional arousal of our bodies.  Faster stronger heartbeats accompany threat and other challenges, but this may translate as anxiety, sadness or anger depending on how we register and interpret these changes. This Proof-of-Concept grant aims to verify the innovation potential of the ideas and methods linked to the ERC advanced grant 324150 ‘Cardiac Control of Fear in the Brain’.  HeartRater will characterise an individual along dimensions of interoceptive ability, including the unique interaction between heartbeat signals and the processing of threat and fear.  The Proof-of-Concept of grant will consolidate intellectual property rights and strategy, develop a technical prototype and undertake groundwork for marketing.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'BIOengineered grafts for Cartilage Healing In Patients (BIO-CHIP)' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Spontaneous healing of articular cartilage injuries is poor and untreated defects predispose to osteoarthritis. Current therapies, including innovative autologous cell-based treatments, cannot predictably and reproducibly restore cartilage structure and function. BIOCHIP will carry out a multicenter, prospective phase II clinical trial to treat knee cartilage injuries using engineered grafts based on autologous nasal chondrocytes (NC). As compared to typically employed articular chondrocytes, NC have a higher and more reproducible capacity to generate mature cartilage tissues. Importantly, molecular/mechanical characterization, large size animal studies and a phase I trial carried out by BIOCHIP partners have already shown the compatibility of NC upon implantation in a joint, with promising preliminary clinical results.BIO-CHIP’s specific objectives are:(1) To test the hypothesis that the maturation of NC-based cartilage grafts improves the clinical efficacy in the treatment of cartilage lesions (108 patients will be recruited to reach statistical significance)(2) To extend the range of clinical indications of NC-based grafts to so far untreatable pre-osteoarthritic lesions (‘kissing’ cartilage lesions in a sheep model)BIO-CHIP capitalizes on clinical experience of 4 reference centers for cartilage surgery, on established GMP manufacturing capacity and on preparation for commercial exploitation by a strong orthopedic device company. Demonstration of therapeutic efficacy of the new treatment will address a large clinical need (over 2 million cartilage defects/year worldwide), improve quality of life (reduce pain & disability in the young, delay prosthetic implants in the elderly), exploit a commercial opportunity (prospected revenues of up to 130 million €/year) and redu