RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'RESHUFFLING OUR UNDERSTANDING OF FUNDAMENTAL RIGHTS LAW IN EUROPE' in the context of a Horizon 2020 call.

assistant: **Objectives**

Our continent is being shaken by a set of major challenges ranging from economic to security, refugee and rule of law crises. These events place unprecedented pressure on the institutional framework designed to hold Europe together since the second world war. The EU has emerged as the key player whenever the most fundamental rights of individuals are at stake. This is somewhat surprising. Since the 1950s, scientists have understood the European edifice as being based, on the one hand, on the Council of Europe designed to protect European values and fundamental rights in particular; and, on the other, on the EU intended to advance European (economic) integration. Therefore, it is the Council of Europe, an international organization distinct from the EU, that was initially placed at the forefront of fundamental rights protection. Yet, the EU is now taking the lead on setting fundamental rights standards. Benefits may be considerable where the EU offers strong institutional support. There may however also be a profound mismatch between the new function of the EU and its constitutional design. For instance, it may be inappropriate to address religious discrimination in employment – such as regulating the conditions for headscarf bans - through the same harmonization tools ensuring the free movement of goods. Are new concepts and legal tools needed to ensure trust in the EU system?The principal investigator, an EU constitutional and fundamental rights expert, will critically assess the shift in the nature of the EU’s contribution to European fundamental rights law with a view to better defining the new function of the EU in the field and making recommendations to improve its ability to perform such a function. For that purpose, she will draw on three aspects: legal research
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'SUBSTITUTION OF ENVIRONMENTALLY HARMFUL CHROMATES FOR PASSIVATION OF ZINC PLATED PARTS WITH MOLYBDATE PHOSPHATE' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Validation of an innovative process technology designed to substitute toxic chromates for passivation of zinc plated parts with a newly developed composition of molybdate and phosphate called Molyphos. Molyphos has been tested extensively at laboratory scale and is patented, but is not yet used at industrial scale. The project aims at demonstrating that MolyPhos matches chromate based passivation at competitive cost. Large scale end-users of zinc parts/components include VOLVO
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Cell cycle control in the fission yeast schizosaccharomyces pombe', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Research objectives and content Depending on environmental conditions, Schizosaccharomyces pombe can enter either pre-mitotic or premiotic DNA synthesis or remain in stationary phase. This decision point is called START. The MBF complex (pgsedololp72resllp73res2) is required for exit from START: it is responsible for the transcription of several genes necessary for entry into the S phase of the cell cycle. However the mechanisms that regulates the complex remain unknown. The main objective of this research project is to determine the contribution of the MBF complex to the cell cycle progression. Further, since cells lacking functional p85cdcl 0 or p73res2 are unable to undergo meiosis, we wish to determine the role of the components of the MBF complex in differentiation. In mamrnalian cells, the complex of the E2F/DP proteins induces the expression of several genes required for S-phase progression. In fact, the E2F/DP and the MBF complexes activate the expression of similar genes, such as ribonucleotide reductase and S-phase cyclins. Thus, even though they lack homology at the molecular level, they can be considered functional homologues. The E2F/DP complex is negatively regulated by the RB family of tumor suppressors. Loss of this regulation leads to premature cell cycle entry that may lead to tumor formation. The characterization of the molecular events that regulate S phase entry in a genetically manipulatable system such as S. pombe may lead to further insights into the regulation of this important cell cycle checkpoint in mammalian cells. Training content (objective, benefit and expected impact) During my Ph.D. in Barcelona University and my first postdoctoral experience at the Dana Farber Cancer Institute (Harvard Medical School) I have acquired a strong backgroun
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Examination of the measurement and control of ozone emissions during welding and allied processes (WELD-OZONE)' (WELD-OZONE).

assistant: **Innovation**

The aim of the project is to investigate, compare, and if needed, further develop test methods for measuring the ozone emission rates during welding. Ozone emission rate data are produced using the most applicable methods identified though a critical literature review. In parallel, welders exposure to ozone are measured under carefully controlled conditions. The method(s) which provide the best correlation between ozone emission rate and exposure to ozone at the workplace is identified and, if needed, further developed. The method(s) is validated in round robin tests. A revised draft standard for ozone emission rate measurement is produced and presented to CEN/TC 121.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Tomographic 3D Ultrasound for Safe and More Cost Effective Vascular Diagnostics and Treatment Planning' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Annually, cardiovascular disease (CVD) causes over 4m deaths in Europe and 17.3m deaths globally, and is expected togrow to over 23.6m by 2030. It accounts for 40% of deaths in the EU and costs the EU economy almost €196bn each year.2D ultrasound scans are currently the primary choice for vascular diagnostics. Due to low sensitivity, a limited field of actionand the lack of volume information, patients are often referred for CTa, MRa and catheter angiography for the detailedimaging required for diagnosis and treatment planning. Referrals delay treatment, exposes the patient to risks associatedwith radiation and contrast mediums and increases costs. This presents a need to improve the speed and safety of thediagnosis of vascular conditions for rapid treatment, as well as to improve workflow efficiency and reduce costs. The projectconsortium will further develop the piur tUS system, a 3D freehand tomographic US system capable of rapid, safe andaccurate reconstructive 3D quantifiable vascular imaging. It will provide a low cost and reproducible imaging solution that willreduce the need for referrals and be an effective preventative screening tool for CVD. We aim to complete and publish theresults from 4 CVD clinical studies to generate the clinical evidence required for CE marking and clinical validation for marketuptake. The 4 clinical applications studied will provide a solution for conditions most frequently referred for detailed 3Dimaging to maximise the cost-benefit to clinics of purchasing the piur tUS system. The project consortium combines piurimaging’s expertise in medical device development and commercialisation with 3D imaging specialist ImFusion GmbH andmedical device product development and manufacturing experts ACMIT. The clinical input for the product develo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'CEPHEUS: COST EFFICIENT PASSIVE HOUSES AS EUROPEAN STANDARDS' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

Cost-efficient reduction of the total energy consumption (for space heating, domestic hot water and household electricity) of new residential buildings by at least 75% to a level of no more than 42 kWh/ (m²a). This can be achieved without adding new active components to the building. Instead, the heat requirement is reduced to such a low level that a comfortable interior climate can be achieved both in winter and summer without a separate heating or air-conditioning system. The energy demand for domestic hot water and household appliances is also extremely reduced. Thus, the capitalized costs (investments in the building incl. planning and building services plus running costs over a period of 30 years) of the building are not higher than in an average new building. Passive houses shall be introduced as a new building standard to the European marketplace. This standard creates the basis to cover the remaining energy requirement totally by renewables.As the project is just about to begin, not many results are available yet. However, it has already been found in all projects that houses built to passive house standards can certainly be marketed, despite partially unfavourable framework conditions. Where difficulties in marketing or delays or modifications of individual projects have arisen, this was generally not due to the required passive house standard but other circumstances. The calculations of the Passive House Institute carried out until now show that the passive house standard will be achieved in all projects.Passive houses are buildings in which a high level of comfort can be achieved in winter and in summer without a separate heating or air-conditioning system- the house 'heats' and 'cools' itself purely 'passively'. In a passive house, a combination of largely p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'From Insightful Science to Innovative Health: Strengthening Translational Capacity and Talent Interoperability in Vaccine and Biologic Research & innovation'.

assistant: **Innovation**

Following the COVID-19 pandemic, biologicals and vaccines became regarded as salient pillars for disease prevention and control. However, strengthening preparedness for and response to health emergencies request more commitment and intersectoral cooperation between academia and industry to set up efficient strategies against diseases, whether through surveillance, detection, diagnosis, prevention, or treatment. VISION (Vaccine & bIologics reSearch & innovatION) intends to implement an intensive intersectoral and bidirectional knowledge/know-how transfer programs in order to reinforce vaccine and biologics development capacities with manufacturing, upscaling, or delivery capabilities among a consortium with Institut Pasteur de Tunis (Tunisia), Darnitsa (Ukraine), Torlak Institute (Serbia) and Connectinnov (Tunisia) as academic (AC) & non-academic (NA) widening members; Institut Pasteur (France) and Center for Genomic Regulation (Spain) as academic research non widening (NW) organizations; Merck (France) and Quantoom (Belgium) as NW&NA partners. VISION comes as a critical lever for R&I ecosystem feeding post-pandemic needs and matches the WHO mRNA Transfer initiative aiming to enhance widening production capacities and help achieving a comprehensive health coverage towards Sustainable Development Goals. VISION will in fine streamline the discovery, testing and production of biologics and vaccine candidates including mRNA-based technologies. VISION's main objectives are threefold: (i) endow Widening Talents with advanced knowledge and skills in Vaccine and Biologics Development, (ii) promote more impactful collaboration through training and mobility between AC and NA sectors towards an efficient high-performance translational R&I environment with an Open Science pillar, an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Dissecting the constraints that define the eukaryotic DNA replication program' under Horizon 2020.

assistant: **Concept**

DNA replication is essential for the perpetuation of life and, yet, it is also a major source of genomic instability that can lead to cancer and other human diseases. Despite the vast efforts invested in establishing the origins of genomic instability, the mechanisms that coordinate faithful genome duplication while ensuring its integrity remain unknown.This dilemma is molecularly best exemplified by single stranded DNA (ssDNA), which inevitably results from unwinding the double helix due to replication fork progression, but is at the same time a vulnerable intermediate that can lead to severe genomic lesions. Thus, maintaining an appropriate balance of ssDNA is a paramount challenge for replicating cells. My own work has significantly contributed to this concept by showing that eukaryotic cells have limited resources to guard its ssDNA, and that exhaustion of these resources (due to increased overall levels of ssDNA) causes a lethal fragmentation of the genome termed ‘replication catastrophe’ (RC). To prevent this terminal scenario, ssDNA levels and DNA replication activity must be constrained by yet uncharacterized mechanisms. In eukaryotes, where DNA is simultaneously replicated at multiple sites throughout the genome, this represents a particularly challenging task. Understanding how this is molecularly accomplished could transform our view of the very principles of DNA replication regulation, and also reveal potential therapeutic avenues to exploit RC in the treatment for cancer.With the present proposal I will address this challenge by investigating how ssDNA maintenance is enrooted in the regulatory principles of DNA replication. I will dissect the mechanisms that, globally and locally, constrain replication activity to prevent genomic instability. By using novel
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Depth-Resolved Optical Nanoscopy', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

A fluorescence microscope for the noninvasive imaging of the structure and dynamics in thick 3D systems with 3D sub-diffraction-limited resolution and at extended penetration depths would have a broad spectrum of applications in both the physical and biological sciences. Conventional fluorescence microscopy techniques, such as confocal and two-photon microscopy, lack the spatial resolution required for measurements at the nanoscale, whereas state-of-the-art 3D super-resolution optical microscopy methods offer limited penetration depth (<5 microns). In the proposed project, I aim to develop a new microscope that combines molecular photoswitches, fluorescence self-interference and light-sheet microscopy to optically section a thin layer deep in thick semitransparent samples with 3D sub-diffraction-limited resolution. I will then test it for potential physical and biological applications of single molecule detection. The first specific aim is to develop a depth-resolved self-interference photoswitching nanoscope employing novel high-throughput and sub-diffraction-limit fluorescence interferometry. The second specific aim is to map with 3D nanometer resolution the motion of photoswitchable fluorescent probes deep in soft materials. This study will open up new possibilities for precise measurements of the heterogeneity and mechanical properties of the nanoenvironments of soft matter at extended depths and may ultimately assist in developing superior biomaterials and nanomedical therapeutics. The third specific aim is to in situ image with 3D nanometer resolution the muscle thick filament system in fixed Caenorhabditis elegans nematodes at both the ventral and dorsal ends (separated by ~80 microns). This demonstration, if successful, will provide unique 3D super-resolution in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Multi site & multi stage enterprises logistic control system' under Fourth Framework.

assistant: **Concept**

The objective of MUSSELS is the realisation of a general logistics control system for multi-site and multi-stage environments. It is expected to resolve the problems of the traditional Production Planning and Control (PP&C) approaches, by increasing the co-ordination level between the various actors in the logistics chain, enabling them to function as a virtual enterprise.The tool will be built up with different but integrated modules and will be able to run autonomously as well as in connection with existing PP&C systems. Two modules play the role of high performing 'engines' able to manage the operations in each production unit: the planner and scheduling systems allows finite capacity planning integrated with Just-in-Time (JIT) techniques, while the Kanban control system is a shop control system, based chiefly on JIT-Kanban methodologies, and improved by a wide use of IT. The shop control system will be based on experience and results of EP 8178 (IKS). Integration to these two modules will create a push-pull approach. Logistics chain analyser module is a simulation tool. It is designed to analyse business process performances along the logistics chain, to suggest suitable planning techniques and decisions in order to improve previous modules. The fourth module, multimedia system, is an interactive self learning training system, created to facilitate human interaction and to build end users' skills. It will assist people in overcoming their resistance to new techniques in industrial environments. It is expected that MUSSELS will contribute to increased productivity, logistics, resources utilisation, stock reduction, shortened lead times and an increased service level through capacity balancing between the layers of the supply chain. Two pilot applications for the plas
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Combinatorics of Networks and Computation'.

assistant: **Concept**

Networks are present in our lives in numerous different environments: to name just a few, networks can model social relationships, they can model the Internet and links between web pages, they might model the spread of a virus infection between people, and they might represent computer processors/sensors that have to exchange information.This project aims to obtain new insights into the behaviour of networks, which are studied from a geometric and computational perspective. Thereto, the project brings together researchers from different areas such as computational geometry, discrete mathematics, graph drawing, and probability. Among of the topics of research are enumerative problems on geometric networks, crossing numbers, random networks, imprecise models of data, restricted orientation geometry. Combinatorial approaches are combined with algorithms. Algorithmic applications of networks are also studied in the context of unmanned aerial vehicles (UAVs) and in the context of musical information retrieval (MIR).The project contains the work packages: “Geometric networks”, ""Stochastic Geometry and Networks"", “Restricted orientation geometry”, “Graph-based algorithms for UAVs and for MIR”, and “Dissemination and gender equality promotion”. The project connects researchers from 14 universities located in Austria, Belgium, Canada, Chile, Czech Republic, Italy, Mexico, and Spain, who will collaborate and share their different expertise in order to obtain new knowledge on the combinatorics of networks and applications. ""


**Keywords:** network, geometric graph, randomness, algorithms, UAV, musical information retrieval