RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Decoding mitochondrial selective autophagy in synaptic homeostasis during ageing' (SynaptoMitophagy).

assistant: **Innovation**

Age-dependent accumulation of damaged mitochondria and synaptic loss represent early pathological hallmarks of brain ageing leading to neuronal death. Mitochondria-selective autophagy (mitophagy) is triggered to eliminate defective organelles promoting cellular and organismal survival. Mitophagy declines with age, while its induction extends lifespan and confers neuroprotection across diverse species. Although the pivotal role of mitophagy in neuronal physiology is steadily emerging, its contribution to synaptic homeostasis remains elusive.Building on our previous pioneering studies, SynaptoMitophagy aims to reveal the molecular underpinnings of age-dependent synaptic impairment, focusing on mitochondrial maintenance and turnover. We will combine the nematode Caenorhabditis elegans, which offers a well-defined nervous system, with cutting-edge technologies, such as super resolution imaging, microfluidics and optogenetics, to manipulate spatiotemporally mitochondrial damage and monitor synaptic mitophagy at nanoscale resolution, in vivo. Mammalian neurons will be used to address the functional conservation of synaptic mitophagy components.The objectives are four-fold: 1) Establish mitophagy reporters for in vivo monitoring of mitochondrial fate at synapses during ageing and under neuroprotective conditions 2) Use optogenetic tools to stimulate synapse-restricted mitochondrial damage and, thereby, to detect mitophagy induction and its contribution to neurotransmission. 3) Characterize the synaptic defects and assess behavioral deficits arising from mitophagy impairment. 4) Conduct forward genetic screen for synaptic mitophagy modulators, towards augmenting mitochondrial quality control and resistance to age-related synaptic failure. The cumulative results of this proposal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Development of Smart PHBV films with microencapsulated spirulina as TUnable food contact MATerials' (STUMAT), addressing dissemination and exploitation.

assistant: **Impact**

The substantial global food waste linked to plastic-based packaging highlights the urgent need for sustainable alternatives. Polyhydroxybutyrate-co-hydroxyvalerate (PHBV) is a promising eco-friendly option, but its use in the food industry is limited due to inadequate mechanical properties. Attempts to improve PHBV materials with existing additives have encountered issues like biodegradation challenges, poor dispersion, and undesired crystallization. However, novel bio-based ferulic acid derivatives are predicted to solve this problem by tuning PHBV’s properties through enhancing free volume between polymer chains while maintaining physical interactions. Additionally, transforming PHBV into smart materials for food contact applications remains unexplored. Encapsulation of Spirulina platensis extract (C-PS) could be a way forward due to its advantageous natural chemical composition (known for pH-responsive color-changing properties). However, conventional encapsulation methods often result in unstable microbeads. To overcome this, droplet millifluidics can be employed to achieve stable encapsulation of C-PS in alginate microbeads, enabling PHBV to become smart for the first time. The current project aims to create new additives to improve the mechanical properties of PHBV through green chemistry and modeling approaches, to encapsulate C-PS in alginate microbeads using droplet millifluidics during a secondment to produce smart materials through green manufacturing and test them for spoilage detection. Aligned with the EU’s ""farm to fork"" priority, STUMAT will allow me to combine interdisciplinary skills gained from both the host and secondment on the additive synthesis and microencapsulation respectively to integrate a new generation of bio-based additives and microenca
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Design as driver of innovation and competitiveness'.

assistant: **Innovation**

DESMA is a training network including 4 leading universities, 4 design consultancies and 4 product and service organizations in the area of Design Management - an area of research and practice that is concerned with the dynamic intersection of design and management. The great potential of design as a driver of innovation and competitiveness is increasingly celebrated in the popular and scholarly management press, by European policy makers as well as manufacturing and service companies. However, the marriage between design and management is not always easy. The two fields have different historical roots, educational traditions and research foci. A divergence reflected in professional cultures and skills of practising designers, engineers and business graduates.In order to fully exploit the exciting potential of design as driver of innovation and competitiveness, we need researchers who can who can bridge the design and management divide within industry as well as academia. This entails being able to work at the intersection of the two fields, with a deep understanding of their respective languages, epistemologies, and practices, as well as the different perspectives of academia and practice.The overall objective of this programme is to create and support a new generation of design management researchers with this capability.The project is based on close collaboration among the partners through courses, conferences and other common activities, as well as through the research projects. While the consortium represents leading actors in the field of design management today, we have adopted an open strategy aiming to include and collaborate with other universities, companies and interest groups in Europe. The aim is to create a common platform for progressing design managemen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Restructuring in marginal rural areas (the role of social capital in rural development)' (RESTRIM) under Fifth Framework.

assistant: **Objectives**

This project will inform questions at the heart of EU policies for rural areas and peripheral, marginal regions. New patterns of diversity and differentiatation are emerging, and localities have uneven capacities with which to face this uncertain future. The purpose of this research is to enquire into those characteristics of marginal rural communities, which build their capacity to diversify their economies and to maintain their competitiveness and social cohesion in this context. Specifically, the research will explore those dimensions of a community's social capital" which have been identified in theoretical accounts as underlying successful performance, competitiveness and cohesion. The study will be conducted in six countries. The results will indicate how policy intervention can help build social capital and so assist in promoting endogenous rural development and the future competitiveness and cohesion of marginal rural areas."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Innovative pump to carry out asbestos level measurements by remote control through IOS/ Android App' in the context of a Horizon 2020 call.

assistant: **Objectives**

Asbestos is an element seriously harmful to health, causing long-term diseases, especially respiratory ones. Although its use in the EU has been banned since 2005, there are many old buildings likely to contain asbestos and be a source of danger to people, especially building maintenance workers. In addition, asbestos-related diseases result in a huge amount of healthcare costs each year and a comparable number of fatalities to car accidents. WLTS is a French company based in Grenoble with nearly 20 years of experience in the sampling and analysis of asbestos in the air and materials. It is an entity accredited by COFRAC, French accreditation body, and characterized by its rigor and independence. The most significant customers are asbestos removal companies. WLTS has developed PUMP3M2D, a smart pump to measure the level of asbestos in the air, equipped with an electronic card that allows its remote control through iOS / Android Apps. This pump allows an improvement and simplification of the sampling process, avoiding the displacement of the technical staff to the worksites anywhere in the world and their exposure to asbestos. PUMP3M2D will be a disruptive revolution in the market of sampling and will provide a competitive advantage with the competitors, it will allow to carry out the internationalization of the company, achieving a ROI of 3.42 and 19 new employees in 3 years.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'A study of the magnetic spin-fluid ground state, and the kagome antiferromagnets (h3o)b3(so4)2(oh)6 (where b3+=fe3+,cr3+,and v3+)', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Research objectives and content The study of the physical properties of experimental these Kagome antiferromagnets is important to our understanding of fundamental magnetic order as they possess a new type of magnetic ground state, the spin liquid, resulting from the unique connectivity of the lattice. The jarosite series offers the best examples Kagome systems and so provides the best opportunity to investigate this new type of magnetic order. Detailed investigation will be done on the effect of spin quantum number (both integer and half-integer) and diamagnetic dilution on the low-temperature physical properties of these materials, and on the competition between different possible ground states. Characterisation of the magnetic properties of these materials requires a large number of complimentary, techniques (e.g. neutron diffraction, muon spin resonance, Mossbauer spectroscopy, specific heat and SQUID susceptibility). Training content (objective, benefit and expected impact) This proposal is to study these materials using the wide range of techniques and expertise available within the framework of the materials science division of the CEA The CEA provides an excellent environment of experience and expertise in which not only to learn about the experimental techniques required to research the physics of new magnetic technologies, but to develop the broad knowledge of the topical problems in magnetic behaviour that is also necessary. Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'HUNTING GHOST NEURONS IN THE NEUROENDOCRINE HYPOTHALAMUS' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The hypothalamus contains heterogeneous neurons that dictate behaviours and physiological functions through cross-talk mechanisms with peripheral hormones. Neuronal diversity is the key to enabling hypothalamic functions and, according to the neuroscience dogma, is mainly preset during embryonic life. But what if this model is incorrect? Can neuronal heterogeneity be plastically modulated throughout adult life as well? Here, based on my published work and solid preliminary results, I propose that special 'Ghost' neurons in the hypothalamus display plastic mechanisms of cell-identity reprogramming to accommodate neuroendocrine functions in adult life under physiological conditions. Such identity plasticity can become maladaptive and contribute to neuroendocrine disorders such as obesity. My central hypothesis is that atypical 'Ghost' neurons are hidden within mature populations of neuroendocrine brain neurons. The Ghostbuster project will hunt down these brain cells and uncover their role in physiology and metabolic disease. A multidisciplinary approach will be used toward this goal, uniting lineage tracing strategies, nutritional interventions, single-cell profiling of hypothalamic neurons, bioinformatic analyses, and viral-based tools for targeting Ghost cell-related genes. These strategies will be combined with behavioural, metabolic and hormonal assessments of mice models of Ghost neuron loss or gain of function. The project will overturn the dogma that post-mitotic neurons have negligible cell-reprogramming capacity and revolutionise our understanding of how brain functions are plastically regulated throughout life. We will shed light on key molecular targets that allow the reprogramming of neuronal functional identity for therapeutic use and provide a novel framewo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'EC DEMONSTRATION UNIT OF AN EXTREMLY LOW-ENERGY CONSUMING CALENDER' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

A calender is arranged at the end of a paper production line. It has the task to provide paper thickness compensation in the um range over the entire paper width and to give the paper the required surface finish. With conventional technology this involves high energy losses due to the process. Because of a new process technology (paper thickness compensation of fine profiling not with thermoelectric heating elements but with hydraulic control elements) and a new technology (substitution of the solid grey cast iron roll tube of lOOmm(!) by a thin-walled chemical fibre-reinforced plastic composite tube) losses due to the process are extremely minimised. The demonstration plant of a calender in the paper industry is to provide verification so that compared with conventional technologies about 85% energy (normally mainly electrical energy) for so-called fine profiling can be saved.The innovation of the process innovation of today' s thermal control process is the paper thickness compensation in the calender. The paper thickness compensation in the um area today is handled by a great number of electrical heating elements on the massive steel roll in the distance of a couple of millimeters. These heating elements are creating an expansion of the steel roll diameter so that the paper thickness compensation is possible in the area of some micromes. This type of possible fine profiling should be reached in the demonstration unit with the help of many hydraulic pressure elements in the mating roll where the roll shell will be manufactured out of FRC material. So the full flexibility for the fine profiling could be realized over the entire roll face width. The innovation of the process technology lies in the change of the fine profiling process technology away from external energy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Algorithms and Tools for Mining Biological Sequence Data'.

assistant: **Concept**

The goal of this proposal is to set up an interdisciplinary research training in the area of bioinformatics algorithms, that should lead to establishing a new level of expertise in certain techniques, methods and algorithms for handling the ever-increasing volume of biological sequence data (DNA, RNA, proteins). Bioinformatics is one of the flourishing research fields at the Computer Science Department  of Ben-Gurion University in Israel, including four four faculty members and numerous growing collaborations with biological partners. In general, Ben-Gurion University is one of the most rapidly developing in Israel and provides a vibrant research atmosphere.Besides extending the range of competences to new research areas and increasing the actual expertise , this training will continue a recently started fruitful and promising collaboration between the applicant and the host institution, and should result in a series of high-level publications and new software tools available to the bioinformatics community. Moreover, the training is expected to lead to further collaborative projects involving the partners of the present proposal.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The desire of explore to reach new frontiers' under Horizon 2020.

assistant: **Concept**

Wanderlust is the Zaragoza European Researchers Night 8th edition design to aproach researchers to general public. We chose Wanderlust because it means travel, it menas the desire to know more, to reach new places, to be inspired from different cultures. We think it is a metaphore, and it represents the spirit of the researchers life, and it easy connect with people. It also a good approach to the european dimension of the research, and it is easy researchers identificate themself with the project.  The event will be a ""fiesta"" of outreach in Zaragoza. The last year we have increase awareness of public, we increase visitors, researchers involve and we managed to create a group of stakeholdes who support the project.  The key of the susccess of our event is the know how of ESCIENCIA who manage the project in Aragon from 2011, becouse it is a SME speciallize in science communication. We support researchers to deseign their activities, we train them how to speak to public, and we work both with enthusiastic public and science reluctant public in our project.  The wanderlust is a perfect claim to address public at large. It is an easy way to citizens to become part of the event. The feeling of explore is a common point for most public.  We are working with Educational deparments of Spannish, Aragon and Zaragoza governments. We have already signed letter of endorsement of Aragon and Zaragoza.  The project has a Science Fair as a point ot reach pupils. It is an effective way to rise awareness prior to the event, to involve schools and communicate ""science is fun"" to young people. In the three last edition we have pool the participants and the remark the Science Fair as ""Fun and Challenged"".  The European Researchers Night in Zaragoza will take place in the Center of the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Testing network for verification of air emissions abatement technologies' (AIRTV) targeting Sixth Framework.

assistant: **Abstract**

The European Commission adopted an ambitious Action Plan (COM (2004) 38) to improve the development and wider use of environmental technologies. Many new environmental technologies have great potential to improve the environment and, at the same time, boost the competitiveness of companies.The main objectives of the Action Plan are: To remove the obstacles so as to tap the full potential of environmental technologies for protecting the environment while contributing to competitiveness and economic growth. To ensure that over the coming years the EU takes a leading role in developing and applying environmental technologies. To mobilise all stakeholders in support of these objectives.One of the actions included in this Action Plan is the improvement of testing, performance verification and standardisation related to environmental technologies, with the aim of providing a European instrument for verifying through commonly recognised and transparent protocols the performance characteristics of environmentally sound technologies (EsT).The results of the verification should be reported to decision makers, regulators, buyers and to the general public through appropriate information means, with the aim to accelerate the penetration of new technologies in t he market. The Action Plan proposes the creation of networks of specialised centres to carry out the testing and assessment of clean technologies based around families of technology sectors. AIRTV will become a powerful tool for the efficient implementation of this Action Plan.The overall, strategic objective of AIRTV is to speed up the implementation of EsT in Europe by establishing a system of their verification, proving the benefits of EsTâ's use for environment and human life conditions AIRTV will pro vide reliable and in