RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Spin Engineering in Flexible and Functional Two-Dimensional Quantum Material Devices' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Can spin integrated circuits (Spin-ICs) with low power-high speed processing capabilities be realized? What are the key ingredients necessary to catapult present-day spintronics to make such a leap? The emergence of two-dimensional (2D) quantum crystals provides new impetus for exploring ambitious ultralow-power and ultrafast speed prospects of spintronics and nanomagnetism. Atomically thin 2D quantum materials like graphene have created novel possibilities for pure spin current communication, functionalities, and controlling spin phenomena, for inventing entirely new kind of spin components, that could pave the way for spin ICs. SPINNER aims to unleash these prospects leveraging the PI’s pioneering leadership and recent innovations in flexible graphene spin circuits, breakthrough longest spin communication in graphene, and precision characterization of 2D magnetic crystals, aiming for three highly ambitious objectives: (1) Achieving strain control of spin currents and spin Hamiltonian in 2D materials. (2) Enabling field-free pure spin current torque functionalities in graphene spin circuits. (3) Controlling ultrafast spin currents at 2D spinterfaces. The proposed new experiments in SPINNER build upon the PI’s expertise in state-of-the-art spin and charge transport, µ-Hall magnetometry, advanced nanofabrication, and device engineering, augmented with new strengths in magneto-optic Kerr effect and ultrafast spin dynamics experiments. Designed for unprecedented engineering of spin materials and devices, the success of SPINNER will reveal new performance, low-power spin functions, determining the ultimate efficiency and speed of pure spin-current operations for Spin-ICs, leading to multiple new scientific and technological breakthroughs. Realizing SPINNER will make a signi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'New generation advanced phosphorus-containing flame retardants designed via machine learning and genetic algorithm' under Horizon Europe.

assistant: **Concept**

Polymeric materials show advantages of high performance and low cost and have been widely used in modern society. Epoxy resin (EP) as one of the most important polymers, has been widely employed in construction, automotive, and aerospace industries, etc. In Europe, EP market has exceeded 410.60 kilo tons per year. However, the intrinsic flammability of EP makes them potential hazards to human life and property. Due to environmental concerns, incorporating phosphorus-containing flame retardants (P-FRs) into EP has been approved as an efficient approach to improve their fire safety. However, customized target P-FRs design is still hindered due to limited known structures and mechanisms. For example, in EP, two P-FRs with similar chemical structures but different chemical surroundings showed more than 10 times difference in flame-retardant efficiency. Therefore, how to reveal the structure–property relationship of P-FRs and achieve new high-efficiency P-FRs design based on subtle differences in these chemical surroundings (such as group positions, spatial configuration, etc.) pose significant challenges. The overarching goal of the ambitious yet feasible project (FireDesign) is to design novel high-efficiency P-FRs using machine learning (ML) and genetic algorithms (GA). More specific objectives include: O1) to establish the linkage between chemical structure of P-FRs and their flame retardancy efficiency, and to predict target properties of flame-retardant EP by ML; O2) to design optimal P-FRs molecular structures by GA in tandem with ML-based predictive model; O3) to synthesize high-efficiency P-FRs according to the designed molecular structures. FireDesign is a typical multidisciplinary approach requiring complementary expertise from the host (flame-retardant design, fi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'ESTABLISHING THE EU-MEDITERRANEAN ICT RESEARCH NETWORK'.

assistant: **Innovation**

The first objective of Join-MED is to create a sustainable network of ICT research organisations in the Medi-terranean Partner Countries (MPC) and Europe, reinforcing the Research Cooperation between these two regions on a wider scale. To achieve this, Join-MED will organise a series of networking events in the MPC that will bring researchers from different MPC and EU together. Furthermore, it will support the creation of institutionalised networks on a cross-regional basis, suggesting appropriate methodologies for accomplishing this.To support all networking activities Join-MED will develop an interactive web-based directory of research organisations from both regions, the MPC and EU.To help unfold the potential of the research capacity across the MPC, where R&D is still driven by national initiatives with very little cross-regional co-operation, Join-MED will promote closer research co-operation across the region. This will achieved by moving from country-focused networking events to cross-regional ones.The second objective of Join-MED is to support the Information Society policy dialogue and the co-ordination of national policies on international S&T co-operation in the MPC. This will be achieved by for-mulating a harmonised MPC ICT policy and through an open dialogue, among the MPC as well as with Europe.Join-MED will establish close links with existing and emerging co-operation projects addressing the MPC, in particular the NCP Network, to exploit synergies with the different objectives they pursue, maximise impact and contribute to the definition of co-operation strategies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Supergravity theories and supersymmetric spacetimes'.

assistant: **Concept**

The aim of this project is to apply in the university of Valencia (my institution of origin) the skills aquired in the Department of Applied Math- ematics and Theoretical Physics during the time I was a HCM Fellow. This will be done with the members of the Department of Theoretical Physics in Valencia, but the colaboration with some members of DAMTP will also continue. These skills consist of some knowledge of supergravity theories (at the classical level) and their different formulations; the relation between extended supergravity and Bogomolnyi bounds for the ADM energy; the concept of Killing spinors of a spacetime, and the concept of black hole, specially in 2 + 1 dimentional spacetimes. Consequently, the research will be focused in the following main directions : - The study of the interplay of quantum theory, supergravity and positive energy theorems in low dimensions. - Positive energy theorems in four dimensions and their associated solitons. - A deep study of the coupling of matter to the different three-dimensional anti-de Sitter theories.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'A novel mechanism to regulate gene expression in the brain' (DD-PD), addressing dissemination and exploitation.

assistant: **Impact**

Development of advanced therapeutics based on non-small molecule drugs for brain diseases is an area of intense research. Experimental work using viral vector-mediated in vivo gene therapy showed great potential as a competitive therapeutic strategy for clinical use in neurodegenerative diseases. AAV vectors are now in early clinical trials stage for treatment of Parkinson’s disease. Although it is deemed very important to have controlled expression in the brain, none of the currently tested strategies have implemented an approach that can be exogenously controlled. Regulation of the therapeutic intervention is important not only for safety reasons but has important implications for tuning the delivery of the therapeutic molecule to the individual needs of the patients, i.e., personalizing their treatment. The core of this proof-of-concept application is to develop a novel gene regulation system as a product for clinical use in patients with Parkinson’s disease. The applicant has assembled a strong team of experts that can take this exciting idea that has spun out of his ERC-funded research to an early business strategy and bridge to commercialization. The work will include filing of new IP, a proactive use of novelty search, formation of a dedicated start-up company for handling the new IPR as well as in-licensing of related IP, and sketching a path towards commercialization via obtaining regulatory authorization, investigation of strategies for large-scale production of the product.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'A Data Platform for the Cognitive Ports of the Future' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

DataPorts will boost the transition of European seaports from connected and digital to smart and cognitive, by providing a secure environment for the aggregation and integration of data coming from the several data sources existing in the digital ports and owned by different stakeholders, so that the whole port community could get real value from this data in order to improve their processes, offer new services and devise new AI based and data driven business models. To this end, DataPorts will design, implement and operate an Industrial Data Platform (Cognitive Ports Data Platform) that:  i) connects to the different digital infrastructures currently existing in digital seaports, enabling the interconnection of a wide variety of systems into a tightly integrated ecosystem, ii) sets the policies for a trusted and reliable data sharing and trading based on data owners rules and offering a clear value proposition, and iii) leverages on the data collected to provide advanced Data Analytic services based on which the different actors in the port value chain could develop novel AI and cognitive applications. DataPorts project involves the design and implementation of the platform, its deployment in two relevant European seaports connecting to their existing digital infrastructures and addressing specific local constraints, a global use case involving these two ports and other actors and targeting inter-port objectives, and all the actions to foster the adoption of the platform at European level. This project will imply that tools, platforms and systems running in the different seaports all across Europe will benefit from the DataPorts industrial data platform, in order to create an even more trusted, reliable and efficient way of conducting businesses in Europe and to reinfo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Reactive control protocols for cyber-physical systems'.

assistant: **Concept**

Cyber-physical systems (CPS) are physical and engineered systems whose operations are monitored, coordinated, controlled, and integrated by a computing and communication core. Systems of this type feature tight interactions between the system's computational and physical components and have attracted increasing attention and investment in both the USA and Europe, for its potential impact on a wide variety of industrial sectors, including aerospace, automotive, chemical production, civil infrastructure, energy, healthcare, manufacturing, materials, and transportation. While most targeted applications of cyber-physical systems are evidently of safety-critical nature, e.g., next generation transportation systems, power grid, and medical devices, how to affordably build and efficiently certify these systems as safe, reliable, and high performance remains one of the grand challenges of CPS research.The proposed research, which lies at the interface of control engineering, computer science, and applied mathematics, aims to bring together a variety of analytical, computational, and experimental tools to address the design and certification challenges in cyber-physical systems. More specifically, it seeks to (1) develop a hybrid systems based modelling framework for networked cyber-physical systems, (2) formally synthesize correct, robust, reactive control protocols for cyber-physical systems from high-level, rigorous specifications that are pertinent to the safe, reliable, and more autonomous operation of cyber-physical systems, and (3) validate and demonstrate the correct-by-construction methodology with numerical simulations and experiments using autonomous mobile robots. Hybrid systems, formal methods, and robotics are three of the key fields the proposed research will dire
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Dynamic Lighting Optimization for Enhanced Occupant Health and wellbeing: A Digital Twin Approach Integrating Behavioral Insights' under Horizon Europe.

assistant: **Concept**

The impact of energy-efficient lighting systems on occupant health and well-being is often not thoroughly studied. Further, the human behavioural response is barely acknowledged while using the predefined control curves in building management systems, resulting in inefficiency, discomfort, and health problems, along with increased economic costs due to energy wastage and reduced productivity. This study will develop a digital twin paradigm extension for dynamic light optimisation based on behavioural insights and occupant needs (DyLiOpt) by mapping user responses and continuously optimising lighting during the operational phase using a Building Management System tailored to occupant needs. To analyse individuals' interaction with varying lighting conditions, three distinct settings within university spaces will be analysed by integrating mental models and the Theory of Planned Behavior to understand how attitudes, subjective norms, and perceived control shape occupant preferences for lighting. A key innovation of this study is the integration of Bayesian inference, enhancing the stochastic models with a probabilistic framework that accounts for uncertainties and variabilities. This approach will refine the models, enabling continuous updates based on new data. The Bayesian optimisation will be implemented within a digital twin platform, utilising patented autonomous optimisation technology to facilitate autonomous and semantic optimisation and dynamically adjust lighting parameters in real time, aligning with predicted occupant behaviour and lighting requirements. This research aims to set new standards in occupant-centric lighting optimisation, contributing to the health and well-being of occupants and energy efficiency in built environments while we race towards a cli
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Black Hole Stability' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

The discovery of black holes, first as explicit solutions of Einstein equations of general relativity, and later as possible explanations of astrophysical phenomena, has revolutionized our understanding of the universe. From a mathematical perspective, a central issue is to investigate the stability of these fascinating objects. This is the focus of the present proposal containing the following work packages:-Kerr stability conjecture. This concerns the nonlinear stability of Kerr black holes which form a 2-parameter family of explicit solutions to Einstein vacuum equations. It has become, since its discovery by R. Kerr in 1963, a central topic in general relativity, first during the golden age of black hole physics, and in the last twenty years in mathematical relativity. These efforts have led to the recent resolution, by the PI and collaborators, of the conjecture in the slowly rotating case. The goal of this work package is to tackle the general case.-Black hole stability with matter. Breakthrough concerning the stability of Kerr for Einstein vacuum equations opens the door to other physically relevant cases in the context of Einstein equations coupled to matter. This work package aims at proving the stability of charged Kerr-Newman black holes for Einstein-Maxwell equations, Kerr back holes for massless Einstein-Vlasov equation, as well as the stability of Kerr-de Sitter black holes in the case of an arbitrarily small cosmological constant.-Price's law and Kerr stability. An open problem concerns the optimal decay rate for perturbations of Kerr that can be achieved in the Kerr stability problem. The analogous problem for corresponding linear toy models is known as Price's law. Obtaining an optimal decay rate in the context of the Kerr stability problem would not on
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Transcriptional Adaptation and Genetic Compensation' (TAaGC) targeting Horizon 2020.

assistant: **Abstract**

Organisms utilize several mechanisms to compensate for the damaging consequences of genetic perturbations.  One such mechanism is the newly identified process of transcriptional adaptation (TA): in this process, certain deleterious mutations trigger the transcriptional modulation of so-called adapting genes.  In some cases, e.g., when one of the upregulated genes is functionally redundant with the mutated gene, TA leads to functional compensation.  Notably, unlike other modes of compensation, TA is not triggered by the loss of protein function.  This unexpected observation has prompted studies into the machinery of TA and the contexts in which it functions.  Following our discovery of TA (Rossi et al., 2015), we have shown that in zebrafish embryos and mouse cell lines, mutant mRNA degradation triggers this process (El-Brolosy et al., 2019).  We also observed TA in C. elegans and found that small RNA biogenesis, in addition to mutant mRNA degradation, is required for this process (Serobyan et al., 2020).  While these and other studies have documented the importance of TA and its occurrence across phylogenetically distant organisms, several key questions remain in terms of how TA arises and how prevalent it is.  In this proposal, we aim to investigate the mechanisms that underlie TA, including 1) what determines which genes are targeted as adapting genes during TA, and 2) how the expression of these genes is modulated during TA.  These studies will be carried out in zebrafish, C. elegans, mice, and multiple mouse and human cell lines, capitalizing on the genetic and biochemical approaches available in each model system, while simultaneously allowing us to analyze the conservation of the mechanisms underlying TA.  In addition, we will investigate the relevance of TA in hu