RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'The Centrioles Role in Male Infertiliy'.

assistant: **Innovation**

Applying cutting-edge technology like cryo-electron tomography, subtomogram averaging and single-particle cryo-electron microscopy to sperm cells, I aim to uncover structural details of sperm centrioles.As most other cells in the human body, sperm cells carry two centrioles called the proximal and the distal centriole. In the field of reproduction biology, it is widely accepted that these organelles are essential for the process of fertilization. One of their many important functions for this process is to provide centrioles for the zygote, as oocytes lose their own centrioles during maturation. Yet, the molecular mechanisms that determine their exact role in mediating fertility is not entirely understood.Concurrently, infertility is increasing globally and so is the demand for treatment, commonly summarized as Assisted Reproductive Technology (ART). The success rate of ART is, however, only between 30-40% and even lower for women older than 35. One of the underlying reasons is that in up to 60% of the cases, male infertility is idiopathic. These numbers underpin the urge of improving our understanding of sperm biology and the molecular mechanisms of fertilization. This project defines three main objectives to achieve this:1.Resolve the ultrastructure of sperm centrioles by applying cryo-electron tomography.2.Isolation and high-resolution structure determination of the proximal centriole by cryo-electron microscopy.3.Comparison of the centriole ultrastructure of sperm from fertile and infertile individuals.A comprehensive structure-function investigation in a native setting will shed light on how centrioles are embedded within the neck of sperm cells. At high resolution, proteins that are associated to the centrioles and link them to surrounding structures can be identi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Do Particle Properties Modulate bioaccumulation, Trophic Transfer and biomagnifications of engineered nanomaterials: Role of Particles size, shape and surface coating? - BTBnano' (BTBnano), addressing dissemination and exploitation.

assistant: **Impact**

BTBnano will use state of the art knowledge and techniques to quantify single-walled carbon nanotubes (SWCNTs) and gold ENMs in cells and tissues. The objectives are to: (1) systematically quantify bioaccumulation and biodistribution of SWCNTs (as a function of size) and Au ENMs (as a function of size, shape and surface coating) in Daphnia magna and Danio rerio at chronic exposure conditions, (2) study the influence of particle size, shape and surface coating of Au ENMs and size of SWCNTs on their trophic transfer along an aquatic food chain, and (3) study the potential for biomagnification of SWCNTs and Au ENMs in the food chain when mass and particle number concentration are considered as dose metrics and develop a model for predicting biomagnification of ENMs based on the proper dose metric. Bioaccumulation and biomagnification of Au ENMs will be quantified by measuring mass and particle number concentration using inductively coupled plasma (ICP)-mass spectroscopy (MS) and single particle (sp)-ICP-MS. (sp)-ICP-MS will also be used to differentiate between ionic and particulate bioaccumulation of Au ENMs. Laser ablation-ICP-MS will be used to in situ quantify cell-to-cell heterogeneity of the intracellular distribution of Au ENMs. Combination of thermogravimetric analyser with fourier transform infrared and gas chromatography/mass spectrometry will be optimized for quantification of SWCNTs in tissues. The novelty of the project is in developing approaches for quantification of carbon-based and metal-based ENMs in biological matrices. BTBnano includes both training me in new advanced techniques and transferable skills and the transfer of knowledge to the host institution. Results have the potential capacity to support the ENM risk assessment and provide room for furthe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Isolating and investigating the components of biosphere - atmosphere gas exchange with process-based models and measurements of stable isotopes' (ISIS), addressing dissemination and exploitation.

assistant: **Impact**

The aim of this proposal is to improve our understanding of mechanisms, controlling factors and coupling of gas exchange between the atmosphere and terrestrial ecosystems. On the one hand, we have a solid understanding of gas exchange processes at the leaf/cell level. On the other hand, we need to interpret data at the ecosystem scale. We will employ stable isotope techniques to bridge the gap between the two.Physical transport or biological activity during plant and soil gas exchange produce simultaneous changes in the concentrations and isotopic signatures of gases in canopy air. The interpretation of such changes requires a process-based knowledge of the isotopic signatures of ecosystem fluxes and their natural variability. To this end,1. we will develop a process-based model of ecosystem isotopic gas exchange. The model will simulate carbon, oxygen and water fluxes and their isotopic signatures in a novel multi-tracer approach to account for the close coupling of the cycling of carbon, oxygen and water at the ecosystem level.2. we will calibrate the model with measurements of the isotopic signatures of gas exchange during photosynthesis and respiration and during ecosystem gas exchange. A combination of chamber and eddy covariance techniques will be applied to provide flux and integrated ecosystem observations.3. we will determine in laboratory experiments the plant metabolic parameters relating to leaf/cell level mechanisms that are not well constrained but important for model predictions and the interpretation of field measurements.The process-based knowledge of isotopic gas exchange will directly contribute to ongoing efforts to partition ecosystem exchanges into photosynthesis and respiration. It will also improve the capacity of stable isotope methods as tools
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Smart structural diagnostics using piezo-generated elastic waves' to be submitted under Fifth Framework.

assistant: **Abstract**

It is proposed to develop a system based on piezo-electric diagnostic technology for the remote semi-continuous monitoring of hot-spots in structures such as oil or gas pipelines, storage tanks, double-hull ships or other industrial installations. Experiments with proof-of-concept specimens indicates that the proposed approach has the potential to detect, locate, identify and size various types of defects. This is done by analysing anomalies in elastic wave pattern received by an array of smart piezo-electric sensors permanently mounted on a monitored structure. Specially designed piezo-generators cause long distance wave propagation. The sensors signals will be transmitted via tele-communication networks to a control unit, will be processed to identify any damage and an assessment of defects' critically will be made. the system will thereby provide the capability for real -time remote maintenance decision-making.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Phase Change Materials for Energy Efficient Edge Computing'.

assistant: **Concept**

In recent years, we have witnessed an explosion of artificial intelligence (AI) applications which will continue to grow over the next decade. An intelligent and digitized society will be ubiquitous, enabled by increased advances in nanoelectronics. Key drivers will be sensors interfacing with the physical world and taking appropriate action in a timely manner while operating with energy efficiency and flexibility to adapt. The vast majority of sensors receive analog inputs from the real world and generate analog signals to be processed. However, digitizing these signals not only creates enormous amount of raw data but also require a lot of memory and high-power consumption. As the number of sensor-based IoTs grows, bandwidth limitations make it difficult to send everything back to a cloud rapidly enough for real-time processing and decision-making, especially for delay-sensitive applications such as driverless vehicles, robotics, or industrial manufacturing. In this context, PHASTRAC proposes to develop a novel analog-to-information neuromorphic computing paradigm based on oscillatory neural networks (ONNs). We propose a first-of-its-kind and novel analog ONN computing architecture to seamlessly interface with sensors and process their analog data without any analog-to-digital conversion. ONNs are biologically inspired neuromorphic computing architecture, where neuron oscillatory behavior will be developed by innovative phase change VO2 material coupled with synapses to be developed by bilayer Mo/HfO2 RRAM devices. PHASTRAC will address key issues 1) novel devices for implementing ONN architecture, 2) novel ONN architecture to allow analog sensor data processing, and 3) processing the data efficiently to take appropriate action. This “sensing-to-action” computing appro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Immersive Multi-View System for Co-located Collaboration' (IMVIS) under Seventh Framework.

assistant: **Objectives**

Virtual environments hold the promise to provide a shared space in which such collaborative interactions of multiple users with virtual 3D models could occur as easily and smoothly as they would in the real world. Large projection-based stereoscopic displays are the most successful incarnation of such immersive virtual environments. These systems use a fixed view point or track the head position of a single user and compute a stereoscopic image pair for that point of view. Unfortunately, when non-tracked users see these images, the virtual environment may appear severely distorted and it changes shape when users are moving.The project IMVIS will carry out research to develop novel projection-based stereoscopic multi-view systems for co-located collaborative 3D displays for multiple users. The main challenges of the project are: develop projection and projector technology, synchronisation methods and high precision alignment algorithms for multi-projector multi-view approaches for single screen and tiled display configurations develop wireless high speed active and active-passive stereo glasses develop, build and evaluate a commercial quality projection-based stereoscopic multi-view display system for at least six tracked users develop, build and evaluate a prototypical projection-based stereoscopic multi-view system for at least 10 tracked people develop build and evaluate wireless input device prototypes and interaction techniques for collaborative multi-user interfaces in co-located multi-view environments develop, implement and evaluate collaborative automotive application scenarios
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Provably-Correct Efficient Algorithms for Clustering' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Clustering data according to similarity is ubiquitous in computer and data sciences. Similarity between data is often modeled by a distance function: two data points are close if they are similar. This induces a metric space in which each data point is associated to a point of the space. Thus, a clustering according to similarity is a partition of the points such that the distance between two points in the same part is small. Therefore, clustering problems play a crucial role in extracting information from massive datasets in various research areas. However, this problem is hard to formalise: the soundness of a particular clustering often depends on the structure of the data. This induces a gap between theory and practice: on the one hand no guarantee on the practical algorithms can be proven, on the other hand the best theoretical algorithms turn out to be noncompetitive in practice.By focusing on both the algorithms and inputs that are relevant in practice, the PEAC project aims at rigorously analysing the cutting-edge heuristics and designing more efficient algorithms that are provably-correct for both clustering and hierarchical clustering (HC), bridging a gap between theory and practice.Very recently, it was shown that a widely-used local search (LS) algorithm achieves the best approximation guarantees for some specific inputs. We plan to design a faster LS-based algorithm for those types of inputs to achieve both better running time and approximation guarantees than the best heuristics. We will design a non-oblivious LS algorithm to obtain a better than the current 2.675 approximation for k-median.Dasgupta recently introduced a cost function for HC. Using this cost function, we plan to analyse the performances of widely-used heuristics for HC (e.g.: average-linkag
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'A Combinatorial Approach to Machine Translation' (COMTRANS).

assistant: **Innovation**

Machine translation systems, whether rule-based, example-based, or statistical, all rely on dictionaries that are in essence mappings between individual words of the source language and the target language. Criteria for the disambiguation of ambiguous words and for differences in word order between the two languages are not accounted for in the lexicon. Instead, these important issues are dealt with in the translation engines.Because the engines tend to be compact and (even with data-oriented approaches) do not appropriately reflect the complexity of the problem, this approach generally does not account for the more fine-grained facets of word behaviour. This leads to wrong generalizations and as a consequence translation quality tends to be poor. In this proposal we suggest to approach this problem by using a new type of lexicon that is not based on individual words but on pairs of words.For each pair of subsequent words in the source language the lexicon lists the possible translations in the target language together with information on order and distance of the target words. The process of machine translation is then seen as a combinatorial problem: For all word pairs in a source sentence all possible translations are retrieved from the lexicon and then those translations are discarded that lead to contradictions when constructing the target sentence.This process implicitly leads to word sense disambiguation and to language specific reordering of words. As there are many more word pairs than individual words in a language, the information content of our lexicon is vastly higher than that of any conventional lexicon.On one hand, this gives the potential for better translations. On the other hand, it is not realistically possible to construct such a lexicon manually. F
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Dynamic Spatio-Temporal Modulation of Light by Phononic Architectures' (Dynamo).

assistant: **Innovation**

Imaging technologies form the basis of a vast range of products and devices and improvements would have a huge impact both scientifically and commercially. We have identified a key bottleneck, how light is modulated in the imaging system, that we can unlock to achieve a new paradigm in imaging technologies. Spatial light modulators, and similar components, operate sequentially: the light beam is shaped in different patterns but the time interval between patterns is limited by the refresh rate of the device. We will remove this limitation, thereby creating a technological breakthrough; our advance will be to send all possible patterns of the device simultaneously, and encoded in a short nanosecond pulse, creating the concept of parallel beam shaping or dynamic spatio-temporal light modulation device. In Dynamo, we will shape optical beams in two spatial dimensions plus the temporal one. The equivalent refresh rate of the dynamic pixel will start at GHz, although we are confident it will become much higher by the end of the project. To give an idea of our ambition, we compare this improvement in the time to process images with the improvement in the clock frequency of computers: the first general-purpose electronic computer, the ENIAC, had a clock frequency of 100kHz in 1945. It was not until 2000 where AMD reached 1 GHz in their computers. Processing images is broadly similar to processing data so this is indicative of the fifty-year acceleration in the realm of imaging that we will achieve. Dynamo is an ambitious and integrated project that begins by studying the fundamentals of acoustic wave scattering and ends by developing ultra-fast imaging applications in optics. The success of this pathway requires the synergy of the disciplines of physical acoustics, photonics an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Zebrafish colour vision: a functional approach to studying outer retinal wiring strategies' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Colour vision is critical animals to navigate their environment. Here, two or more spectrally distinct cone-photoreceptor types are needed in the retina which must be postsynaptically combined to extract contrasts in wavelength. Bipolar cells make selective connections with distinct cone types at the first synaptic layer of the retina and cone-signal integration by bipolar cells lays the foundation for vertebrate colour vision. However, how bipolar cells form connections with selective cone types and achieve functional integration of these inputs to extract chromatic signals during development remains poorly understood. We will focus on zebrafish that has robust colour vision and study the roles of cone inputs and composition in establishing bipolar cell chromatic wiring and function. We will use a multidisciplinary approach spanning genetic methods, anatomical analysis, physiological recordings and statistical modelling. Drawing on existing genetic tools and marker lines established by the applicant, we will focus on two genetically targeted bipolar cell types: one that is cone-selective and one that is cone-unselective. First, we will use in vivo time-lapse imaging to study how these bipolar cells formation dendritic contacts with cones during development. Next, we will use two-photon functional imaging of light-driven synaptic release from cones as well as both dendritic and axonal imaging in bipolar cells to study how chromatically distinct signals are functionally integrated. Finally, using further lines already established by the applicant, we will genetically silence or ablate individual cone types to study how functional integration and wiring formation are regulated by the activity or availability of cones. These studies will gain insight into the strategies to