RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'European Marine Motorways: The potential for transferring freight from road to high speed sea transport systems' (EMMA).

assistant: **Innovation**

The aim of the project is to evaluate the feasibility and cost effectiveness of high speed sea freight ferry services as an alternative to long distance transport of freight by road.The specific objectives are :i) to analyse the existing volume of by-road freight and to identify those areas of the Community where transfer to sea routes could be feasible;ii) to carry out an in-depth study of three routes (which will be identified in i) above) in different regions of the Community, to survey the attitides and requirements of potential users;iii) to research and specify the technology, infrastructure, service levels and operating costs required by the sea ferry and port operators to enable them to compete successfully with road transport;iv) to forecast demand for a sea ferry service on each route, to ananlyse its commercial viability, to identify any impediments to the introduction of a viable service and to make recommendations on how they could be overcome;v) to evaluate the impact of these sea ferry services on road transport flows and on employment and to draw conclusions on the feasibility of the concept,Main expected deliverables and status (C, R or P)*5 reports will be produced during the course of the project (R)Final Report (P)*C = Confidential R = Restricted P = PublicDeadlines for deliverablesReports on task 1+2: Mar-97Report on Task 3: Nov-97Report on Task 4: Jun-98Report on Tasks 5+6: Dec-98
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'New mechanisms and concepts for exploiting electroactive Polymers for Wave Energy Conversion', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Wave energy has a great potential as renewable source of electricity. Studies have demonstrated that significant percentage of world electricity could be produced by Wave Energy Converters (WECs). However electricity generation from waves still lacks of spreading because the combination of harsh environment and form of energy makes the technical development of cost effective WECs particularly difficult.This Project introduces a new class of Polymeric WECs (PolyWECs), characterized by the employment of Electroactive Elastomer (EE) transducers. The goal is to introduce a radical change in the traditional architecture of WECs that usually includes three basic components: mechanical wave absorbers, a mechanical transmission and a power take-off system. Due to their nature, PolyWECs can be conceived in a way that such three components are integrated into a single deformable lightweight and low-cost polymeric element. EEs have been largely investigated in the form of actuators for robotics and ICT applications. Preliminary studies on energy generation through EEs demonstrated their great potential in terms of cost effectiveness, efficiency and reduced complexity. Due to their intrinsic low mass, flexibility and resilience, as well as their capacitive nature and high voltage operation, EE technology perfectly matches the requirements of WECs.The Project investigates on new concepts and mechanisms for wave energy harvesting that are based on EEs through a multidisciplinary approach that includes competencies on WEC design/tests, fluid dynamics simulation/test, control/mechatronics and material science. The aim of the Project is to develop new knowledge and new technologies aiming at:(1) optimizing EE materials for WEC applications,(2) conceiving new electro-mechanical configura
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'THE SYNTHESIS OF DIAZOBENZOFLUORENE ANTITUMOR         ANTIBIOTICS: LOMAIVITICINS A, B AND KINAMYCIN C' (LOMAIVITICINS).

assistant: **Concept**

The proposed research describes a strategy for the convergent synthesis of diazobenzofluorene containing antitumor antibiotics Lomaiviticins A and B as well as the structurally related Kinamycin C.  They are potent DNA cleaving agents and exhibit remarkable activity against a broad spectrum of cancer cell lines.  These structurally novel antitumor antibiotics have a unique cytotoxicity profile, compared to other known DNA-damaging anticancer drugs such as adriamycin and mitomycin C, which may suggest a different mechanism of interaction with DNA.  However, the currently limited availability of these compounds isolated by fermentation and the present lack of any methodology to generate synthetic analogs could hamper further research in the analysis of these highly potent DNA-cleaving agents.  Access to these natural products as well as their analogs by means of chemical synthesis, would enable the scientific community to elucidate their mode of action and the origin of their cytotoxicity.  Thus, in the absence of an alternative state of the art and given the potential of these molecules to become therapeutic cancer agents, the main objectives of the proposed project are:  a) the development of a synthetic methodology for the convergent synthesis of lomaiviticins and their analogs, b) extension of this methodology towards the synthesis of the structurally related antitumor antibiotic kinamycin C, and c) the design and synthesis of structurally diverse diazobenzo[a]fluorene analogs aiming to identify new cytotoxic agents and some of the structural features required for their biological activity.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Making a choice for life – Cellular and molecular basis of coral larvae settlement and metamorphosis.' in the context of a Horizon Europe call.

assistant: **Objectives**

Corals form the basis for some of the most diverse marine ecosystems on the planet. Yet these unique ecosystems have suffered tremendous harm due to anthropogenic influences and are predicted to be among the most adversely affected habitats under the foreseen changes in climate. Among these changing conditions are the occurrence and composition of microorganisms in the coral’s habitat, which are affected by changes in temperature and pH. Corals associate with several specific microorganisms, that govern central aspects of their complex lifecycle, such as the recruitment of larvae, a process that ensures health and resilience of coral reefs. While the central role of biofilms is established in tropical coral species, the vast deep-sea cold-water coral species are less well studied. Lophelia Pertusa is a framework-forming cold-water coral with a global distribution and important ecosystem function -however whether larval recruitment depends on biofilm abundance and composition is unknown. It is therefore urgently required to study this fundamental process in cold-water species to assess and mitigate environmental threats to this unique ecosystem.The proposed study will pioneer investigations into the mechanistic basis of cellular and molecular signal recognition in cold-water coral larvae, taking advantage of the specialized settlement behavior and recent advances in sequencing technology. Here, I will use an interdisciplinary approach, at the border of bacterial recognition, development and sensory biology. I will combine the power of single cell patch clamp electrophysiology, behavioral- and molecular analysis to address central questions about sensory biology in cold-water corals and thereby, the project will produce fundamental knowledge about coral habitat selection
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Irrigation and Society: ""levadas da Madeira""""' in the context of a Seventh Framework call.

assistant: **Objectives**

Overall objective: The present project aims at analyzing the historical construction and development of irrigations systems by a society. It emphasizes the role of technology and institutions for construction, water management and control. The research examines how irrigation organization has been crafted over the time, until today and how the present governance system reflects historical transformations within the society and its segments. Addressing the relations of a particular society to irrigation the project contributes to enlarge the existing knowledge of these relationships in different world contexts. The context of the project is the island of Madeira in relation to its fragile resource: The set of ancient and modern systems of canal irrigation called “levadas”, is the main scene where this research has to be implemented. The network of irrigation channels is impressive. Through the Mediterranean, there is no situation where exists such density of watercourses. Madeira provides an ideal position to interrogate universal social theories in irrigation, while at the same time contributing to the regional history and anthropology of irrigation agriculture. The project fixes as milestones the following goals: a) The production of a technological geography of irrigation systems b) An interpretive anthropological study of selected irrigation systems c) An interpretation of the modern water governance d) In addition a portrait of some of the irrigation cultural patterns of Madeira society. These objectives will be achieved by means of an innovative strategy to investigate irrigation technology and institutions in ‘their context’. Results: Assessment of social history and organisation of Madeira irrigation will be produced. In addition, the research project through the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Recursive Engineering electronic Properties of Artificial energy Materials with multi-Pulse Spectroscopy' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Organic Photovoltaic (OPV) cells are one of the most promising energy conversion materials of our modern world due to their high-mechanical flexibility, robustness, and low-cost production. However, a crucial drawback remains: their low energy conversion efficiency. A reason for this can be ascribed to electronic-vibrational dynamics affecting the ultrafast charge separation occurring in the material upon light absorption. Substantial efforts have been made to defeat this problem, however the incomplete understanding of the elementary mechanism governing the conversion process has restrained further advancements in this direction. In REPAMPS (Recursive Engineering electronic Properties of Artificial energy Materials with multi-Pulse Spectroscopy). I will deliver a first-principles theoretical description of the charge transfer mechanism governing the energy conversion for a prototypical OPV, the P3HT-PCBM blend, and introduce the novel Spectrally Engineered Control (SEC) methodology to direct the charge transfer process towards higher power conversion. A TDDFT methodology will be used to parametrize the P3HT-PCBM heterojunction in its environment, and a molecular dynamics protocol will be adopted for a realistic modelling of the dissipation and spectral bath. Quantum dynamics with explicit description of the external fields and calculation of various time-resolved optical spectroscopies will be simulated. The signals will be validated in collaboration with an experimental group. Nonadiabatic dynamical processes (e.g. conical intersections) affecting the charge transfer and the environment role will be carefully investigated. Last, I introduce the SEC approach combining optimal control theory with the analysis of the spectra, representing a solid strategy for the photoco
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Fake News Recognition applying Service-based Cross-Media Analytics' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The phenomenon of fake news is as old as human’s ability to communicate. Recently, technology has made it easy to spread fake news with unprecedented speed towards the unprotected public, which has resulted in undesired external influence in European elections and referenda (Brexit, Catalonia). Though a variety of fact checkers have arisen out of nowhere, current solutions fail on many aspects: they are primarily based on manual activities, focus mainly on politics and political statements and are highly country-/language specific. Due to the speed and sheer size of the Internet and Social Media platforms, manual defence against fake news is futile. Automated solutions are required involving automatic algorithms that quickly identify fake news and tag them as such, allowing Europeans to make educated, correct decisions. At SAIL LABS, we develop an alternative fact checker: TruthCheck. This combines available and novel technologies such as Machine-Learning algorithms, Trust Modelling, Natural Language Processing, and Speech-, Image- and Video-Recognition to verify feeds from TV, Radio, Newspapers, Internet and Social Media in 31 languages on a semi-automatic basis. TruthCheck will be available as free version to the public, while licenses are offered to enterprises, NGOs and governmental institutions. In absence of a clear market leader we intend to take the opportunity to become first-comer in this segment, thereby targeting the fast-growing market of media analysis. Through this project, we intend to assess and develop the required commercial and technical work that it needs to ensure successful and swift market launch.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Optimization of Free Space Optical Communication Link based Drones for Search and Rescue Operations in the Arctic Region' (FSOCFORSAR) under Horizon Europe.

assistant: **Objectives**

The Arctic region is witnessing more frequent shipping accidents than ever which require accurate search and rescue operations. The existing communication systems use drones with radio frequency (RF) technology, which has limited bandwidth and cannot offer 4G/5G connectivity due to harsh weather constraints. It further limits the capacity of drones and affects the resolution of images and videos. The current research proposes to design free space optical communication (FSOC) link-based drones that can enhance connectivity between multiple drones and rescue ships as well as the capacity of drones to produce high resolution images and videos. The proposed FSOC-based drones can provide highspeed connectivity than the existing RF technology. The research will collect atmospheric turbulences data from the Arctic region and use it for designing the FSOC link. Furthermore, to enhance the capacity of FSOC-based drones, the research will design advanced multiplexing schemes (Mode Division Multiplexing and Orthogonal Code Division Multiple Access) and to ensure link stability, omnidirectional receiver will be designed. The research will further evaluate the performance of proposed FSOC link under the impact of various atmospheric turbulences. The expected outcomes of this research will lead to the optimisation of FSOC-based drones in expanding search areas and improving communication systems for SAR operations in the Arctic region.


**Keywords:** Free Space Optics, Drones, SAR, Mode Division Multiplexing, Optical Code Division Multiple Access
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Dopamine d3 receptor ligands : a novel approach to the treatment of drug addiction' under Fifth Framework.

assistant: **Concept**

We previously showed that a highly selective but partial agonist at the dopamine D3 receptor prevented cue-induced cocaine-seeking behaviour, without having itself addictive properties or affecting the rewarding properties of cocaine. This unprecedented property suggests the therapeutic utility of such medication in human addictive disorders by inhibiting craving and preventing relapse. Hence the major objective of this programme is to develop pharmaceutically one partial D3 receptor agonist and to assess in clinical trials (up to phase IIa) its activity in drug addicts. Meanwhile potential back-up compounds will be synthesised and their activity assessed in a set of screening and specialised biological tests. An additional objective is to unravel by neuroanatomical, neurochemical and electrophysiological studies the neural mechanisms through which partial D3 receptor agonists affect addictive processes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Conference on geographic information systems and remote sensing in mountain environment research' under Fifth Framework.

assistant: **Concept**

Technologies of Geographic Information capture and analysis like satellite imagery and GIS have offered to the scientific geo-community new opportunities for research. The growing awareness of the importance of mountain areas is the reason to launch in September 2002, within the timeframe of the International Year of Mountains - the Conference on Geographic Information Systems and Remote Sensing in Mountain Environment Studies Environment). Its aim is to review the state-of- the-art of GIS and RS in the mountain environment research. A range of specific topics will be addressed during plenary and poster sessions. Important stream of discussion will be technology and know-how transfer to practitioners: local authorities, decision makers. Meeting of specialists from a range of disciplines and a number of countries shall promote interdisciplinary and international research initiatives.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Arrhythmogenic potential of drugs' under Seventh Framework.

assistant: **Concept**

The ability of some compounds to prolong the QT interval of the electrocardiogram and to precipitate Torsade de Pointes (TdP, a potentially fatal arrhythmia) has caused several regulatory interventions, including drug withdrawals. Specific guidelines have been implemented to detect QT liability of new compounds as early as possible. However there is growing evidence that an increase in the QT interval does not necessarily lead to TdP which further increased the regulatory and clinical difficulties. This proposal will assess the arrhythmogenic potential of antipsychotics, antihistamines and anti-infectives (> 250 compounds). It will fulfill this aim by: reviewing the literature on in-vitro and in-vivo preclinical evidence; conducting in-silico modeling to predict the arrhythmic potential through target profiling and docking molecules in existing atomistic models and predicting the effects on hERG K+, Na+, Ca++ channels; analyzing the information in national and international pharmacovigilance DBs of spontaneous reports; conducting prospective case control surveillance on symptomatic QT prolongation; conducting cohort studies in psychiatric and hematology patients; analyzing information from existing studies to assess the association between drug use and various arrhythmia outcomes; and collecting blood samples from cases and drug-matched controls to investigate potential effect modification by candidate genes and a hypothesis generating approach including more than 2000 genes. Healthcare DBs on 27 million persons in 5 countries will be used to calculate rates and relative risks of arrhythmic events during drug use. Predictions on arrhythmic potential will be compared with actual postmarketing risk to assess the predictive value of preclinical markers. All information wil