RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Nanoscale photon absorption and spectroscopy with electrons' (1998-2002).

assistant: **Innovation**

We attach great importance to the training aspect of the proposed Network. All seven teams have considerable experience in successfully training young postdoctoral researchers and graduate students, including many international researchers. The funded young researchers will be full participants in the research activity, and will receive training from the team leaders and other senior staff on research, communication and project management skills. They will participate directly in the programme of collaborative visits to other teams and the annual workshop that forms an essential part of the Network. We shall also organize schools for hands-on training of young researchers in computer simulation techniques from across the Network. We envisage that in most cases the young researchers will come from other NANOPHASE participant teams, and will be well prepared to disseminate new knowledge, techniques and approaches to their home team on their return, and to other teams during their participation in short-term staff exchanges.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'The new standard for sustainable electrification of actuation contributing to a decarbonised Industry 5.0'.

assistant: **Innovation**

Current electric actuators are unable to support high force/ high speed, low power applications. These are important when it comes to tasks a human naturally does such as gripping or clamping. They represent 20% of industrial applications, and their relevance is quickly growing due to their importance in, for example, assembly or robotics.If these 20% cannot be electrified, industries don´t electrify the other 80%. They just keep relying on energy consuming (above 10% of energy consumption in Europe), very inefficient and polluting pneumatic or hydraulic actuators, due to the costs of maintaining two parallel infrastructures. The human muscle is the perfect actuator – it is sensitive, yet shock resistant; strong, yet compact. By uniquely imitating the working principles of the human muscle, we bring the missing piece for fully electrifying the industry. Our patented naXture platform uniquely combines solid-state actuators with integrated micro hydraulic circuits, to consume up to 75% less energy than existing solutions, achieving very high efficiency with ultra-dynamic and precise movement. Our small and light solution can be flexibly integrated in the smallest spaces.Our disruptive technology is protected by more than 100 patents, of which the majority is granted. Moreover, we have proven with leading industry players our ability to electrify processes that previously relied on pneumatics. However, our current cost is prohibitive for most industries, and our production process is manual, thus limiting us to niche markets.


**Keywords:** electrification, high-performance electric actuators, Industry 4.0, Industry 5.0, robotics industrial Internet of Things, IIoT, force density, solid-state actuators, micro-hydraulic circuits, industri
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Geometric Network Modeling and Control of Complex PhysicalSystems' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The proposed project is aimed at the network modeling and control of complex physical systems, using an integrated system approach allowing to deal with physical components stemming from different physical domains, both in the lumped-parameter and in the distributed-parameter case. In order to describe and to manipulate these dynamical models in a systematic way it is mandatory to develop a coordinate-free, geometric framework for their mathematical formulation, especially because of the intrinsic and strong nonlinearities in their system behavior.OBJECTIVESFundamental to modern engineering sciences are the notions of an OPEN SYSTEM having an interface with its environment, and of a NETWORK of open systems coupled to each other through their interfaces. Complementary to the network modeling of complex systems is the DESIGN and CONTROL of systems with a required functionality by coupling open system components. The project is aimed at the use and development of new geometric methods in network modeling, simulation and control of complex technological systems, based on an integrated systems approach allowing to deal with lumped- and distributed-parameter physical components from different physical domains, possibly with strong nonlinearities and variable topology.DESCRIPTION OF WORKIn this project a number of technological areas will be studied using a common underlying geometric network approach. The recently developed framework of port-Hamiltonian systems formalizes the power-interconnection structure of the network model of a physical system through the geometric object of a Dirac structure and represents its dynamical behavior as a generalized Hamiltonian system, providing new powerful tools for analysis, simulation and control. The goal is to apply and further develo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Exploring the underlying mechanIsms of partial leptin reduction towards a non-invasive obesity therapy' under Horizon 2020.

assistant: **Concept**

Leptin regulates energy balance by functioning as a “satiety signal”. When identified 26 years ago, expectations were high that leptin therapies could be used for the treatment of obesity. In contrast to the successful use of leptin for treatment of individuals with lipodystrophy and complete leptin deficiency, pharmacological approaches using leptin therapy for the treatment of diet-induced obesity have been widely unsuccessful. Injecting recombinant leptin in the context of obesity, associated with elevated leptin levels, remains ineffective as central neurons become leptin resistant. Interestingly, Scherer et al. recently published a series of findings that encourages for a conceptual shift. They reported that a partial reduction of circulating leptin levels in the obese state prompts an unexpected systemic response resulting in weight loss, reduced food intake, improved glucose and insulin tolerance and increased energy expenditure - all consistent with leptin re-sensitization in central neurons. The systemic physiological benefits of partial leptin reduction have already been demonstrated. The overall goal of this proposal is therefore to determine the underlying molecular mechanisms that are induced by leptin reduction and trigger leptin re-sensitization. Understanding of these conceptual steps should lead us to explore partial leptin reduction as a viable avenue for anti-obesity and anti-diabetic therapy in the near future.  We aim to determine the peripheral effects of leptin reduction using neutralizing leptin antibodies and advanced mouse genetics. Moreover, we will determine downstream signaling events that are affected in peripheral tissues upon leptin depletion using imaging mass cytometry and transcriptional regulation by single cell RNAseq. Finally, we wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Patent pending gearboxA patent pending gearbox for ships that decrease fuel consumption with 25% (appr 500 ton fuel and 1500 ton carbon dioxide per ship and year)' (OXM), addressing dissemination and exploitation.

assistant: **Impact**

Optixmarine offers a patent pending gearbox for ships with shaft generators and the result is a saving of approximately 500 ton (25%) fuel and 1 500 ton carbon dioxide emission per ship and year.Our product, the gearbox ""Optixdrive"", is today designed and constructed in order to be installation at our pilot customer AB Veritas Tankers vessels “Astoria” in Q1 2016. We have very strong customer interest and after launching the product at the fair Donsö Shipping Meet in September 2015, we are contacted by several new customers every month. Our customers have also stated that there are no attractive alternatives to our product.Worldwide we estimate a total market of more than 7 000 ships with generators, worth 2,1 billion euros. The product is priced to 300 000 euros, which gives customers less than two years in return of investment and this has been confirmed attractive by them.We have eliminated the technical risk with our gearbox through involving leading technical experts and manufacturers, that through calculations and simulations have come to the conclusion that they see low risk with getting our product up and running.On the island of Donsö outside Gothenburg, there are shipping companies that together have 60 ships with shaft generators and therefore potential customers for Optixdrive. Only them together would mean an annual saving of as much as 30 000 ton of fuel and 150 000 ton of carbon dioxide. Imagine the worldwide fleet of ships with shaft generators using Optixdrive, that would mean a saving of 3,5 million ton of fuel and 10,5 million ton of carbon dioxide every year.The team behind Optixmarine believe that transport by sea has a environmental sustainable future and our company has a promising potential to drastically reduce the environmental impact by the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Third Strategy in Tissue Engineering – Functional microfabricated multicellular spheroid carriers for tissue engineering and regeneration' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The field of tissue engineering (TE) pursues a noble goal, driven by the urgent need for tissue and organ repair. It is represented by a fairly large and extremely interdisciplinary scientific community. However, so far TE was not able to deliver to the expectations, with only a few examples of successful clinical translation mostly restricted to a particular disease or tissue type. Despite the fact that all major fundamental bottlenecks of conventional TE strategies have long been identified, a universal solution does not seem to be in sight.In this project I propose to launch a radically new approach, a third strategy in tissue engineering (THIRST), which holds the potential to produce a desperately needed technological breakthrough. THIRST relies on a tissue self-assembly from multicellular spheroids encaged within robust 3D printed microscaffolds. THIRST is enabled by a number of cutting-edge methods, some of which became relevant in the context of TE only recently. In combination, these methods offer a variety of new technological possibilities for the area of TE. The objectives of this project are focussed on establishing the means for automated large-scale production of tissue modules, protocols for microscaffold biofunctionalisation, and demonstrating THIRST potential with highly relevant clinical examples - cartilage, representing avascular tissue, and vascularized bone tissue. A distinct feature of THIRST is its universal applicability, meaning that such a tool-box can be further expanded to encompass other types of tissues without substantial adjustments to the basic tissue assembly procedure. The latter is particularly inspiring, taking into account the considerable regulatory hurdles associated with the development of new TE therapies. Due to its unconventi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Ultrastructural characterization and physiological aspects of vesicle-associated heterotrimeric g-proteins' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

This study will explore the regulation of the transmitter content of secretory vesicles. It is planned to be carried out in collaboration with a group which has long-standing experience in immunocytochemical ultra structural research addressing the biology and pathophysiology of synaptic communication in the CNS. Working in this group, the applicant will learn to use highly sophisticated immuno-electron microscopic techniques. In addition, she will collect experience in the interpretation and quantitative analysis of immunocyto chemical labelling and increase her morphological knowledge. Furthermore, the applicant will also have the possibility to perform also functional studies by a new methodical approach, the FRET technique. Thus, the applicant will extend her spectrum of methods in cellular neurobiology. On the other hand, with her background in the study of mechanisms of transmitter storage and release, the applicant will bring new intellectual aspects into the ongoing research projects of the host group.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'SCENT: Hybrid Gels for Rapid Microbial Detection' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Antimicrobial resistant bacteria are a global threat spreading at an alarming pace. They cause over 25,000 annual deaths in the EU, and represent an economic burden exceeding €1.5 billion a year. Current methods for microbial detection in clinical settings take about 24-36 h, but for slow-growing bacteria, as those causing tuberculosis, it can take more than a week. Early-detection and confinement of the infected individuals are the only ways to provide adequate therapy and control infection spread. Thus, tools for rapid identification of bacterial infections are greatly needed.The analysis of microbial volatile metabolites is an area of increasing interest in diagnostics. Recent works demonstrate that fast microbial identification is possible with chemical nose sensors. These sensors usually present limited stability and selectivity, and require aggressive conditions during processing and operation. Bioinspired nose sensors employing biological olfactory receptors are an alternative. Unfortunately, their complexity and low stability are a limitation. My group recently discovered a new class of stimulus-responsive gels which tackle these key challenges. Our gels are customisable and have a low environmental footprint associated. I intend to further explore their potential to advance the field of odour detection, while providing new tools for the scientific community. I will focus specifically in fast microbial detection. To accomplish this, I propose to 1) build libraries of hybrid gels with semi-selective and selective properties, 2) generate odorant specific peptides mimicking olfactory receptors, 3) fully characterise the gels, 4) assemble artificial noses for analysis of microbial volatiles, 5) create databases with organism-specific signal signatures, 6) identify p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Guided (Ultra)sonic Waves for High Performance Deepwater Pipeline Inspection' (Ultra).

assistant: **Innovation**

This project aims to develop and commercialise VERNE: A non-destructive testing (NDT) system that has the potential to revolutionise underwater inspection of tubular structures by achieving far greater inspection speed and precision compared to existing systems. As the majority of offshore Oil and Gas extraction assets have already exceeded their design lifetime, the need for decommissioning and/or substituting these assets becomes increasingly pressing. However, associated costs are enormous and it will cost nearly €20 billion over the next 10 years to remove around 80 platforms and their associated infrastructure. As asset owners strive to prolong asset lifetime while and minimise risk of catastrophic accidents, the greatest challenge is the inspection and maintenance of subsea structures like jacket foundations and pipelines. In underwater environments the high pressure, seawater and marine life (biofouling) obstruct maintenance operations and accelerate structure degradation. Subsea inspections are currently performed using Remotely Operated Vehicles carrying a payload of cameras, sensors and other equipment. VERNE will dramatically improve on their performance by combining ultrasound and acoustic testing that enable (i) the rapid scanning and defect mapping in a 100m radius around the inspection point and (ii) detailed and precise characterisation once defects are identified. VERNE’s technologies enable inspection of both external and internal surface of structures (e.g. pipelines) without the need to remove anti-corrosion coatings and/or biofouling. As such, VERNE will lead to significant cost savings for asset owners while providing a key competitive advantage to subsea service providers. As such, project partners Dacon and Nardoni anticipate a cumulative turnove
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Dynamic system strategies for climate social tipping points' (DARETOTIP) under Horizon Europe.

assistant: **Objectives**

Society is currently struggling to manage a complex set of socio-ecological challenges related to climate change. Solutionsrange from reducing our consumption to novel technology used to decouple the economy from its impacts. Regardless of thestrategy, materialising the green transition into a low carbon society means crossing a social tipping point (STP).An STP occurs when the collective action of a population reaches leads to wide-ranging systemic change. STPs can betriggered by bottom-up approaches like consumer boycotts, or top-down interventions like policies, tax disincentives, andtrade agreements. The problem is that, so far, STP have only been described qualitatively and the mechanisms beyond theiremergence remain poorly understood.The overall project goal is to provide a deeper understanding of which types of change allow society to move towards a moresustainable status, specifically by unveiling the role of social tipping points in reaching sustainability.I intend to use system dynamics (SD) to study social tipping points quantitatively. SD is a modelling approach to simulatefeedback loops between variables in a system. SD is a perfect fit to the quantitative study of STPs for two reasons. First, it isa flexible tool to model coupled human and natural systems (CHANS), whereby ecological processes exhibit changes overtime under the influence of human drivers. Second, it allows one to determine when changes in elements of the system leadto the crossing of a tipping point and to a different system configuration.My combined expertise in CHANS and SD, supported by my supervisor’s background in sustainability assessment make usan ideal team to conduct this research. Not only that, this fellowship will improve my research profile providing a steppingstonetowards my c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Camel milk chain from milking to powder transformation for applications as an innovative baby-formula milk', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

Recent studies have shown that characteristics of camel milk are very close from the mother's milk. Our project is addressing the both following situations and aims:- To provide an innovative solution to parents with specific nutritional problem with their baby, - To provide efficient and local" solution for infant nutrition through Third World, where camels are very present. The objectives are thus to develop the technologies and knowledge which will enable industrial applications for CAMEL MILK. The project will focus on the entire chain from milking machine, specifically designed for camels, to the transformation into powdered baby formula camel milk. The final product will be an effective nutritional solution in the following situations:- Infants with cow or Soya-protein milk allergy,- Infants with lactase deficiency,- Infants who require a supplement or replacement of mother's milk,- As emergency solution in large famine crises situations."