RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Cyclic peptides as carbohydrates receptors' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

In the last years, considerable effort has been directed to unravel the mechanisms involved in these recognition processes by the design of peptide derived receptors for the selective binding of glycoconjugates. This project will be addressed towards this aim and it will be focused on the development of cyclic peptide receptors for the selective binding of carbohydrates. By using solid-phase combinatorial organic chemistry methodologies, libraries of receptors will be synthesized and screened towards different sugars (e. g. mono- and disaccharides), depending on the cavity shape and size. It is intended to create an efficient tool for the elucidation of the geometric requirements needed for efficient carbohydrate complexatian. Furthermore, due to the enzymatic stability of cyclic peptides as compared to their linear counterparts, these receptors may be interesting targets for drug discovery. The design of these receptors will be based on the stabilizing interaction between the a-face of monosaccharides and aromatic surfaces embedded into a peptide backbone, which may trigger additional interactions between the carbohydrate and the peptide (mostly hydrogen bonds). The modification of the receptor elements in a combinatorial fashion may lead to identification of tight complexes ( e. g. fluorescence assays, BIAcore) which structure will be analyzed (e. g. MALDI- TOF, NMR, Edman degradation, molecular modeling) to obtain the complete interaction pattern between sugar hydroxyl groups and peptide amido groups. Structure/binding efficiency relationship will also be determined towards the development of saccharide bio-sensors, drug or selective carbohydrate transport systems. This project offers the candidate the possibility to improve his knowledge in solid-phase organic chemi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Supporting SME-academia collaboration in the area of biomedical research in FP7 through efficient matching facilities and tailor-made information with special focus on NMS and ACC' goes beyond current state-of-the-art under FP7.

assistant: **Innovation**

SMEs go Health is designed to support SMEs and academic researchers in the 7th EU-Framework Programme (FP7) in order to foster trans-European RTD collaboration. SMEs and researchers shall be encouraged and trained in view of establishing joint innovative research projects by using the funding opportunities for biomedical research of FP7. The planned supporting activities shall facilitate partnering and consortium building by paving the way for an easier identification of competent and suitable research partners with the needed expertise and know-how, especially in New Member States (NMS) and Candidate Countries (ACC). The main activities of the proposed project comprise: -Awareness building and training of SMEs and academic institutions regarding the opportunities and rules of FP7 -Improving the visibility of SME know-how and the expertise of researchers, particularly in NMS and ACC among the European scientific community -Supporting SMEs and academic institutions in consortium building through matchmaking facilities and partnering activities in order to foster RTD collaboration and research project proposal submission in medical technology and healthcare biotechnology of FP7 SMEs go Health will capitalise on the experience and results of SMEs go LifeSciences, providing a European-wide pool of high quality SME profiles and partner searches in a well accepted and user-friendly online database. A well rehearsed network of 29 partners in 27 countries (3 AS, 4 ACC, 8 NMS and 12 old member states) will ensure Europe-wide implementation of the planned activities, addressing the low participation of SMEs in the EU Framework Programme, especially in NMS and ACC, and contributing to the implementation of FP7. Collaboration with related national and international initiatives and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'New combined drying technologies for development of high quality shelf-stable fruit products' (COMBIDRY) targeting Fifth Framework.

assistant: **Abstract**

Rural development requires a continuous effort to increase the added value of agro-production, as the world value of agricultural products steadily decreases. The development of high value added products for international markets requires new technology routes to get high quality and safe products. The objective of this project is to develop a suitable combination of osmotic and microwave drying, which can be used in Africa to obtain shelf-stable, high quality fruit products. A multidisciplinary approach combining research to define optimal conditions for osmotic dehydration, microwave drying and packaging, coupled to quality evaluation will be applied. The reuse of osmotic solution will be studied, thus reducing the environmental impact and adding value. Feasibility studies will be conducted to select the best implementation modes. The consortium includes 4 African and 3 European institutions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'In service inspection robot for structural integrity of tanks filled with hazardous liquids'.

assistant: **Concept**

Leakage from corroded storage tanks, especially their floors, is a major environmental, economic and safety hazard, thus regular inspection of the structural integrity of the world supply of tanks is essential. However external inspection is in principle inadequate, whilst at present all available internal inspection techniques involve emptying the tanks, an expensive, time consuming and hazardous process frequently involving transport of dangerous products to distant alternative storage sites, unacceptable exposure of workers to chemicals during the cleaning operation and weeks of lost production whilst the tank is out of service. The aim of this RTD proposal is to create an amphibious autonomous vehicle, which will enter these tanks internally and inspect their structural integrity without having to empty them.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'A targeted action to support trans-national innovation policy learning'.

assistant: **Objectives**

The overall aim of the project is to promote trans-national collaboration in the field of innovation policy and practice. TRANSPOL will identify issues suitable for trans-national collaboration within each innovation policy theme to be treated throughout the lifespan of the project. Based on the potential collaboration issues identified throughout the project, the TRANSPOL consortium will assist in identifying potential partnerships for concrete INNO-Net and INNO-Action project proposals or proposals under other financing schemes suitable for trans-national policy collaboration.The project also aims to select good practice solutions on designing, implementing and evaluating innovation policy measures at national and sub-national level, and promote their adaptability and transferability to other European countries and regions. Within the TRANSPOL project a mapping exercise throughout Europe on excellent innovation policy measures will also be conducted. A minimum of 36 good innovation policy measures will be collected and further analysed with the objective to promote and test their trans-national transferability. At the same time, a mapping of a minimum of 6 innovation policy measures will be carried out also in the United States. Good practices identified in the US will be analysed, redesigned and adapted in order to be replicated in the European environment.The ultimate aim of the TRANSPOL project is to improve the efficiency of innovation policies, through learning from the best and preparing for more and better trans-national innovation policy co-operation in Europe. TRANSPOL's project activities will include a forum and the organisation of events intended for policy-makers and innovation practitioners for the promotion of trans-national innovation policy cooperatio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Jigsaw puzzles at atomic resolution: Computational design of GPCR drugs from fragments' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Despite technological advances, industry struggles to develop new pharmaceuticals and therefore novel strategies for drug discovery are urgently needed. G protein-coupled receptors (GPCRs) play important roles in numerous physiological processes and are important drug targets for neurological diseases. My research focuses on modelling of GPCR-ligand interactions at the atomic level, with the goal to increase knowledge of receptor function and develop new methods for drug discovery. Breakthroughs in GPCR structural biology and access to sensitive screening assays provide opportunities to utilize fragment-based lead discovery (FBLD), a powerful approach for drug design. The objective of the project is to create a computational platform for FBLD, with a vision to transform the early drug discovery process for GPCRs. As structural information for these targets is limited, predictive models of receptor-fragment complexes will be crucial for the successful use of FBLD. In this project, computational structure-based methods for discovery of fragment ligands and further optimization of these to potent leads will be developed. These techniques will be applied to address two difficult problems in drug discovery. The first of these is to design ligands of peptide-binding GPCRs that have been challenging for existing methods. One of the promises of FBLD is to provide access to difficult targets, which will be explored by combining molecular docking and biophysical screening against peptide-GPCRs to identify novel lead candidates. A second challenge is that efficient treatment of neurological disorders often requires modulation of multiple targets, which also will be the focus of the project.


**Keywords:** Fragment-based drug discovery, molecular docking, virtual screening, G prot
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Integrated biological treatment and agricultural reuse of olive mill effluents with the concurrent recovery of energy sources' in the context of a Fifth Framework call.

assistant: **Objectives**

The olive pulp generated during the two-phase processing of the olive oil contains almost 80% (per dry weight) carbohydrates and thus it could be an ideal substrate for the production of energy in the form of ethanol, hydrogen and biogas (methane). Very limited research has been done so far on making value out of this waste. The proposed BIOTROLL project aims at studying the biological treatment of the olive pulp for the production of ethanol and hydrogen, the subsequent anaerobic treatment of the effluent with the simultaneous production of methane and the agricultural re-use of the final residue as soil improving agent and/or fertilizer. Optimisation of the whole process will take place regarding the optimal combination of the different treatment steps that would be most favourable from both the environmental and financial point of view.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'NOVel cheap and Abundant Materials for catalytic biomass conversion'.

assistant: **Concept**

NOVACAM addresses the development of novel technology to enable the substitution of critical metals in industrial catalysts  (call objective).  The project will aim to develop catalysts using non-critical elements for the conversion of biomass to chemicals and fuels. Catalysts are one of the six major uses of critical metals that are produced as byproducts of mining of primary metals, e.g. platinum group metals and lanthanides. Many industrial heterogeneous catalysts have been developed empirically, such that the role of these critical metals in affecting catalyst performance is not clearly understood. NOVACAM will develop innovative catalysts by applying a “catalysis by design” approach, integrating the complete chain of knowledge from fundamental research to proof of concept. The prototype catalysts will be benchmarked against current catalyst technology. Industrial use of biomass is at an early stage and presents an opportunity to develop the next generation of cheap and abundant catalysts. The main objectives of the project are (i) to understand by a “catalysis by design” approach the requirements for inorganic catalyst systems to speed up elementary reaction steps and valorise biomass with a focus on conversion of cellulose into fuels and chemicals; (ii) using these nanoscale insights to develop novel catalysts based on abundant elements for the conversion of biomass and (iii) to develop three proof of concept studies at  laboratory scale to convert cellulose/sugar feedstocks into fuels and chemicals - specific attention will be paid to catalyst robustness. In this way, the extensive knowledge base acquired in catalysis research will be employed to design novel inorganic catalytic systems. The project will be carried out with a partner consortium in Japan with comp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Induction and control in type systems' (1994-1998) under Fourth Framework.

assistant: **Objectives**

Research objectives and content Induction Many programming languages and proof development systems are based on powerful type theories with a mechanism for inductive definitions. In programming languages, the mechanism -pattern- matching- is powerful but the type systems are logically weak. In proof development systems, the type systems are logically strong -technically, with dependent types- but the mechanism for inductive definitions -elimination principles- is not powerful enough. I propose to remedy to this mistmatch and study pattern-matching in the context of dependently typed systems -with and without subtyping. Previous work by the applicant on congruence types and the theory of labels will be crucially used to define and study the suggested type theories. Control Since 199O, many classical lambda calculi, enriching a typed lambda calculus with control oper- ators, have been studied in the literature and used to give a computationally meaningful interpretation of classical logic. One fundamental limitation of all these calculi is to be non-dependent. The question naturally arises whether the existing results scale up to systems of dependent types. A priori, the answer is far from obvious. Most of the afore cited syntaxes are tailored for non-dependent calculi and cannot be meaningfully extended to systems of dependent types. Besides, earlier work on the Calculus of Constructions has revealed anomalies with excluded middle in an impredicative type theory. Nevertheless, ongoing joint work with J. Hatcliff and M.H. S0rensen shows that it is possible to extend dependently typed systems, and more generally pure type systems, with a computationally meaningful classical operator. I propose to develop this line of work further. My main objectives are to provide a founda
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Heterogeneous Learning for Natural Language Processing' under Seventh Framework.

assistant: **Concept**

A major challenge in machine learning and artificial intelligence is to reduce the dependency in full direct supervision and learn from various undirected resources as well. Most successful machine-learning systems require some amount of human supervision. Currently, a dominant paradigm for building a statistical parser, for example, is to first have human annotators to manually parse a large amount of sentences, and then use the parsed sentences to learn the parameters of the parsing system. For example, a parser built using the Penn Tree Bank, a large corpora of parsed sentences from the Wall Street Journal, is expected to parse well newswire text fragments, but not e-mails, which are different in nature. Yet, one would like to employ all data available from various resources, genres and types to build either a general system or a system that is adapted to a particular task. The goal of the proposed project is to design new paradigms for large-scale learning of natural language problems in various languages from heterogeneous data sources of variable size, quality, amount of supervision and type. Our primary objective is to develop theory, design algorithms, analyze them and build systems for processing written and spoken natural language. Furthermore, the world-wide-web and similar available resources contain a huge amount of heterogeneous collections of data. I propose to make use of the heterogeneous data and based on the tools I will develop to build statistical-based automated systems for various natural language processing tasks, with applications ranging from automatic document classification, via a full range of information extractions to speech analysis and recognition.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The Most Efficient Space Propulsion Ever Put in Space' (HYPERION).

assistant: **Concept**

Deficiencies in propulsion systems—compactness, power, cost-effectiveness, fuel efficiency, scalability, and adaptability—curtail the potential of small satellites in Low Earth Orbit (LEO), hindering mission diversity and longevity. The imminent surge in the deployment of small satellite constellations to fulfill communication, observation, and scientific needs, underscores the urgency of addressing these limitations. ION-X's ambition is to craft the most efficient propulsion system for orbital assets. Our patented ionic liquid electrospray technology with unmatched thrust, ISP, and fuel efficiency, enables the versatility of configuring thrust-to-ISP ratios in-flight, enduring life durations, and vectoring boosts in orbit. ION-X’s transition from technological demonstration to on-orbit operation and, subsequently, market availability will revolutionize the space propulsion paradigm by fortifying satellite mission capabilities and reshaping the course of space exploration.


**Keywords:** Earth Observation / Services and applications, Space data exploitation, Space Debris, Spacecraft, Launchers, Orbital transportation and re-entry systems
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Active Self-Assembly'.

assistant: **Innovation**

Self-assembly is the process in which individual components spontaneously interact to form ordered structures. Biomolecules such as nucleic acids and proteins assemble in dynamic ways, for example they can change their shape, charge, orientation, and as a result they can carry out complex tasks. Experimentalists and engineers are already pursuing biomimetic materials made of reconfigurable adaptive building blocks. However, current theoretical research on self-assembly focuses on components with static shape and interactions, i.e. that do not change during the assembly process. In order to understand the way biomolecules interact and make progress in materials design, a theoretical study of active self-assembly is essential. In this proposal we aim at a deeper understanding of the self-assembly of active particles, through theory, computer simulations and collaboration with experimentalists.