RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Supercapacitive Polymer Electrodes for Directing Epithelial Repair', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

In this project we develop a new approach, using the conducting polymer poly (3,4-ethylene dioxythiophene) (PEDOT) to apply electrical fields (EFs) for guidance of cells. EFs are recognised as important guidance cues in the development and life cycle of human tissues. However, better tools are urgently needed to support experiments and applications. By developing supercapacitive PEDOT electrodes, able to support an ionic flow over extended time frames, we here target the most widely studied clinical application for EF stimulation, accelerated wound healing. Our technology facilitates the transfer from petri dish to device by offering an alternative driving process to metals. In addition, we establish a strategy where electrodes can be recharged in situ, by using intermediate periods of current flow in the reverse direction and below the threshold for triggering a biological response. Ionic flow driven by PEDOT electrodes can, in contrast to metals, be reversed with any small ion present in the electrolyte.The project will be driven in several steps: after proving the principle in scratch assays in vitro, we will proceed to three dimensional culture systems. The versatility of our concept will allow more complex wound healing models to be studied including human ex-vivo models. We will employ microfluidics to make high-throughput screening possible, thereby efficiently mapping EF parameters and especially the effects of sub-threshold stimulation. The ultimate goal at the end of the project is to transfer technology in the form of a polymer based wound-dressing for accelerating repair, the SPEEDER. In summary, we present a new concept which greatly facilitates EF stimulation in vitro and shows great promise for clinical use. Studies will better reproduce the biological si
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Legal Culture under Stalinism in Poland'.

assistant: **Concept**

The objective of the project is to describe the legal culture in Poland under communism on the basis of cultural texts, especially films and literature. No scholarly research of that kind has been done to date. The experience of communism caused Polish citizens to distance themselves from laws and legally binding regulations and to use the strategy of “playing the law”. This means that members of the democratic opposition, while they understood that authorities treated communist law instrumentally, acted as if their basic rights were binding both for them, and for the authorities. The strategy in the long run was of considerable importance for the evolutionary exit from communism. Conducting comparative research on the basis of cultural texts and currently available works of historians and sociologists will allow me to investigate (1) how the contents of these texts reflected and reacted to the oppression from the communist regime; (2) to what extent the rule-of-law environment of Central-Eastern Europe (CEE) is different from that of Western Europe, and (3) to what extent the Polish example might help formulate more general conclusions about the further implementation of EU legal norms in Poland and CEE, and might help us understand the legal culture of new democracies, e.g. countries participating in the Arab Spring.The project will be realized at the SAXO Institute, University of Copenhagen, in close cooperation with main supervisor, Prof. Helle Porsdam. The project will result in at least 3 articles in peer-reviewed academic journals, at least 4 presentations to an international audience, as well as a range of more popular works. It will provide (A) opportunities to acquire and transfer knowledge between Poland to Western Europe; (B) enhancement of my own creative a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Development of a SOftware tool for Predictionof ready-to-eat food product sHelf life, quality and safetY' (SOPHY).

assistant: **Concept**

The SOPHY project aims to develop a web-based software tool for prediction of product safety, quality and shelf life of ready-to-eat products. Fresh cut salads, fruit salads and deli salads were chosen as model food system. Food producers will be able to optimise their raw material selection, product formulation and processing steps virtually. The software estimates the effect of each production step on the safety (growth or survival of relevant pathogens) and shelf life (growth of specific spoilage organisms and/or formation of undesirable by-products) while considering quality (organoleptic characteristics and other quality parameters). The predictive and probabilistic models are based on existing data sets of bacterial growth and quality changes under various conditions generated during previous studies (where available) and data generated during the project. Users will also have the possibility to insert own data, e.g. initial bacterial contamination. The web-based software can be continuously expanded – even after project end - by inserting new data sets (e.g. other food products, different environmental conditions, etc.).Furthermore, the project aims not only to develop predictive and probabilistic models, but also to compile information about different processing techniques, product formulations (e.g. clean label), environmental conditions (e.g. modified atmosphere packaging) as well as hygiene, quality and safety management. These information sheets aim to educate food producers, as they should not only see the effect of different factors on shelf life and pathogen growth calculated by the models, but also understand why. This increased awareness is crucial in improving overall food safety and quality. Information of this nature is essential for small businesses
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Colonial Legacies and Redress: A Digital Mapping Solution for Europe', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Colonialism is often seen as a chapter in history, yet its consequences – interwoven with structural racism and discrimination – continue to affect societies both inside and outside of Europe today. A growing number of institutional and civil society actors recognize the urgency of addressing these enduring legacies. Their efforts encompass policy, legal, and political reforms, historical truth-seeking processes, formal apologies, reparations, restitution of looted artifacts, memorialization, and the dismantling of colonial symbols. These measures and mechanisms, and the broader processes surrounding them are commonly referred to as ‘redress’. However, these initiatives remain highly fragmented, with limited knowledge-sharing and lesson-learning across different contexts.RedressHub will bridge this gap. As an innovative online database platform, RedressHub will leverage advanced data technologies, interactive visualization tools, and participatory design to map and connect redress initiatives for colonial harms and their legacies across Europe. This platform will serve as a dynamic space for a broad user community to engage in groundbreaking cross-sector collaborative justice efforts. It will become an essential resource for grassroots and community actors, policymakers, educators, human rights practitioners, and many other stakeholders to learn about, support, design and implement more meaningful and scalable redress initiatives across Europe—and beyond.RedressHub will thus transform the theoretical insights and methodological innovations from ERC-StG-804151 (Justice Visions) into practical, actionable tools that empower diverse stakeholders to acknowledge and address historical injustices and their lasting impact on contemporary societies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'The role of essential DNA metabolism genes in vertebrate chromosome replication' (DNAMEREP).

assistant: **Innovation**

Faithful chromosomal DNA replication is essential to maintain genome stability. A number of DNA metabolism genes are involved at different levels in DNA replication. These factors are thought to facilitate the establishment of replication origins, assist the replication of chromatin regions with repetitive DNA, coordinate the repair of DNA molecules resulting from aberrant DNA replication events or protect replication forks in the presence of DNA lesions that impair their progression. Some DNA metabolism genes are present mainly in higher eukaryotes, suggesting the existence of more complex repair and replication mechanisms in organisms with complex genomes. The impact on cell survival of many DNA metabolism genes has so far precluded in depth molecular analysis. The use of cell free extracts able to recapitulate cell cycle events might help overcoming survival issues and facilitate these studies. The Xenopus laevis egg cell free extract represents an ideal system to study replication-associated functions of essential genes in vertebrate organisms. We will take advantage of this system together with innovative imaging and proteomic based experimental approaches that we are currently developing to characterize the molecular function of some essential DNA metabolism genes. In particular, we will characterize DNA metabolism genes involved in the assembly and distribution of replication origins in vertebrate cells, elucidate molecular mechanisms underlying the role of essential homologous recombination and fork protection proteins in chromosomal DNA replication, and finally identify and characterize factors required for faithful replication of specific vertebrate genomic regions.The results of these studies will provide groundbreaking information on several aspects of verte
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Enhancing the Research and Innovation Potential of M-ITI through Human-Computer Interaction and Design Innovation' (2007-2013).

assistant: **Innovation**

The goal of the project proposal is to seek funding in order to expand the research and innovation potential of the Madeira Interactive Technologies Institute (M-ITI) of the University of Madeira through the hiring of an ERA Chair in Human-Computer Interaction (HCI) and Design Innovation (DI). The LEAPFROG HCI-DI aims at unlocking the full potential of interdisciplinary research in interactive technologies, while strengthening innovation and knowledge transfer activities in close collaboration with local and global industrial partners and contributing to the smart specialization strategy of Madeira. To this end, funding this project proposal will support the following main activities: (i) Upgrade the RDT capacity and capability by expanding the human potential and fostering a critical mass of researchers with inter-disciplinary expertise in human-computer interaction (HCI); (ii) Improve M-ITI’s innovation potential and impact at the regional, national and European levels, through design-driven innovation. Such approach will unravel the impact of open innovation and crowdsourcing on education, training and knowledge transfer, and extend the creative research capabilities of individuals and organizations in the region and finallty (iii) Raise international awareness about the institute and connect M-ITI and its industry affiliates to the global knowledge networks.As a consequence of these activities we aim to better integrate M-ITI with the European Research Area (ERA) and, in particular, improve the participation of M-ITI and associated entities of the recently created regional system for R&D+I, thereby increasing the level of participation of the institute in the Horizon 2020 program.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Illuminating the role of transcription factor dynamics in development' (TF-Dynamics).

assistant: **Concept**

Understanding how genomic regulatory elements encode when and where genes are expressed in development remains one of the most important open questions in biology. Despite intense study, this knowledge gap persists because technological limitations have obscured an important degree of freedom: time. Recent discoveries made with live cell imaging have defied the textbook view of how transcription is regulated. Hence, the time is ripe to introduce a new paradigm for studying transcription in development—one based on how genes are regulated in living animals as development is actually taking place. Excitingly, we can now exploit the cutting-edge live imaging technology and quantitative approaches that I previously developed in order to visualize transcription factor (TF) concentration dynamics, transcription, and even single TF molecules in live Drosophila embryos to uncover how enhancer sequence regulates transcription in vivo.  This ambitious work will span multiple length scales, from examining changes in TF concentration at the single-nucleus level, to measuring the formation of local clusters of TFs at the locus level, to watching individual protein-protein interactions as they drive transcription at the molecular level. First, we will understand how TF concentration dynamics regulate gene expression. Second, we will uncover how recently discovered dynamic TF clusters or condensates regulate transcription and how their properties are shaped by enhancer sequence. Finally, we will overcome one of the most daunting technical challenges facing the field of transcription by developing a method to directly visualize the transient protein-protein interactions that drive transcription in vivo. Simultaneously visualizing protein-protein interactions and tracking transcription
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Development and demonstration of energy efficient system for accelerated curing during repair and refurbishment of concrete structures' (MCURE).

assistant: **Concept**

This project has been initiated by the 4 SMEs from different European countries who are all committed to participating in the successful research, development and subsequent demonstration of the MCure project in order to improve the quality and curing time of concrete constructions. Over 50% of expenditure in the EU construction sector is on repair of existing structures rather than on new build. The primary material of construction requiring repair in EU is concrete. The annual cost of repair of reinforced concrete structures in Western Europe is in excess of €5 billion, a problem which is likely to be even greater in Eastern Europe. Wide scale research undertaken by EU FP5 project CONREPNET 2004 showed that 25% of structure owners are unhappy with the performance of the repair within five years after the rehabilitation of reinforced concrete structures; 75% are dissatisfied within ten years. This has generated a requirement to deliver more durable and effective repairs to concrete structures. To meet this requirement, this MCure project will scientifically develop a novel accelerated curing approach which will improve the durability, accelerate the curing and consistency of concrete repairs, independent of climatic environment. It will be an energy and time efficient curing system. It will make more efficient use of resources, especially in harsh winter weather conditions due to the system robustness and the effectiveness of the technology in all kinds of weather. This approach will improve the productivity and competitiveness of SME repairs contractors. This technological approach will involve advancements in the fields of remote moisture sensing and concrete compressive strength. Background research has validated the technical concept and the market opportunity. Wit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Organic electrically pumped LASer by engineering of heterostructures in field-effect devices' under Sixth Framework.

assistant: **Concept**

The present project aims at achieving foundational research on a world prime: an Organic Electrically Pumped Laser. Our novel approach is based on the engineering of organic heterojunctions in field-effect devices. On the way to realising the main objective, intermediate results and milestones represent by themselves important sub-objectives: 1. Field-effect device with high electron and hole mobility for organic integrated circuits. 2. High brightness light-emitting organic semiconductor device.  The strategy proposed to reach the ambitious goal focuses on solving the main difficulties, which are commonly faced when targeting this breakthrough: exciton quenching and photon losses. We take advantage of the know-how developed on ambipolar light-emitting field-effect devices with lateral charge injection to explore unprecedented routes towards the electrically pumped organic laser. This novel approach combines the use of high-mobility (field-effect) structures, n- and p-type materials, phosphorescent compounds, the engineering of materials in heterojunctions, as well as of advanced device and photonic technology.  The project activity is expected to have a profound impact on IST-related technologies. Lasers are used daily in a variety of applications. Electrically pumped lasers based on organic semiconductors possess numerous advantages over III-V semiconductor lasers, the most important being the higher integration potential on arbitrary substrates (including glass, polymers and the backend of silicon CMOS), the lower cost and the wider spectral range of possible lasing emission.  The realisation of an electrically pumped organic laser would be a breakthrough in both physics of lasers and organic opto-electronics. The research towards this goal is clearly a long-term one
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'JUST-in-time health emergency interventions - Training of non-professionals by Virtual Reality and advanced IT tools' in the context of a Fifth Framework call.

assistant: **Objectives**

In health emergency care, effective and just-in-time interventions of on-the-field operators can reduce damages to injured citizens. Such damages can be severe and sometimes turn into permanent disabilities, causing high social costs. In most European countries, proper training of operators is still a critical issue. In traditional training, psychological impact of accident scenarios on operators is afforded in real-case situations without being tested in advance. JUST, therefore, addresses training of non-professional health emergency operators, by using advanced IT tools. The project R&D work aims to produce a Web/CD training course, with innovative, certified, multimedia content, as well as a VR-based verification tool.The project's main goals are:(1) to complement traditional courses(2) to check operator capabilities in adopting correct decision-making procedures(3) making optimal use of advanced IT, and(4) in overcoming psychological barriers. Project results will be assessed in four pilot sites, set up in Italy, Greece, Spain, and France through clinical trials. Multi-linguality will, as a result, greatly enhance the European dimension of JUST's R&D work.Objectives:The JUST project addresses the domain of training of non-professional health emergency operators. It aims, through the use of advanced information technologies, certified content, and innovative VR based tools, to provide advanced support for continuous education and training, and to overcome the present weaknesses.The specific objectives of JUST are:(1) development of a Web/CD training course to support the traditional learning phase, based on the collection and/or creation of multimedia content of European relevance,(2) development of a Virtual Reality Verification Tool to check operators capabilities