RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Individualised and self-adapting sound processing for cochlear implants' (ISIFit) targeting Horizon 2020.

assistant: **Abstract**

Cochlear implants (CIs) are successful auditory prostheses that enable people with deafness to hear through electrical stimulation of the auditory nerve. In a CI sound processor, a sound signal is converted into a sequence of electrical pulses. This conversion entails many parameters that should ideally be fine-tuned (fitted) for every individual patient, to account for various anatomical and physiological differences. In current clinical practice, devices are fitted during the initial rehabilitation and yearly thereafter. As fitting is very time consuming, only the bare minimum number of parameters is fitted individually. However, for many other parameters, for which currently the same default values are used for all patients, better speech understanding can be achieved with individual fitting.  Apart from the fitting, CIs do not take into account the neural or perceptual effects of stimulation. The objective of this project is to provide better fitting to individual patients by developing a closed-loop CI that automatically adjusts its fitting and sound processing based on the neural response to speech. To achieve this, we will (1) objectively measure speech understanding, by recording the electroencephalogram (EEG) in response to ecological speech signals, (2) automatically fit a wide array of sound processing parameters accordingly using a genetic algorithm, and (3) develop a wearable closed-loop CI that continuously records the EEG and adjusts the fitting in real-life situations. This will lead to a better understanding of speech perception of people with a hearing impairment, an objective measure of speech intelligibility with many applications in diagnostics, a method to automatically fit CIs, and a novel closed-loop CI. For the patient this means improved speech
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Hierarchical models for visual shape and motion' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

Research objectives and content Object tracking is an important and still difficult problem. For example surveillance applications require the tracking of intruders who might perform complex and erratic motions. The person might for example crawl, walk, run through a gate or jump over a fence. Moreover, once an object has been tracked, additional evaluation is needed on order to decide the exact nature of the motion and to react appropriately. These issues of tracking and interpretation are the focus of this research proposal. The main aim of this research is to build a system which handles object tracking and motion classification simultaneously. Until recently tracking and motion classification have been dealt with as two separate processes. However it is highly desirable to develop systems where classification feeds back into the perception of motion since perception and classification are inextricably bound together. The reasoning behind this approach is that the statistical models used for the anticipation of motion can potentially be adapted for classification. Training content (objective, benefit and expected impact) It is my objective to obtain the academic grade Doctor of Philosophy of the University of Oxford. This research will allow me to explore and contribute to the state-of-the-art of visual tracking. In addition I will reinforce my knowledge in the field of statistical pattern recognition and neural networks. This will be an excellent basis to successfully undertake further research in the field of computer vision in the future. Two aspects make this research particularly interesting. This research itself is the first attempt to bind tracking and motion classification into one model. Furthermore the results have the potential to significantly improve sur
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'European Agricultural Knowledge and Innovation Systems (AKIS) towards innovation-driven research in Smart Farming Technology' to be submitted under Horizon 2020.

assistant: **Abstract**

Smart-AKIS was submitted to the 2014 call, remaining on the reserve list (12/15). For resubmission, all items in the ESR have been carefully addressed: i) more focused approach, addressing only Smart Farming Technology for crop production and using more concrete methodologies; ii) stronger involvement of the machinery industry, with specific support from national Associations and a dedicated working group within CEMA; iii) a Data Management Plan ensuring compliance with H2020 Open Access Policy and inclusion in different thematic aggregators.The project aims at setting up a self-sustainable Thematic Network on Smart Farming Technology designed for the effective exchange between research, industry, extension and the farming community in order to disseminate direct applicable research and commercial solutions and capture grassroots level needs and innovative ideas. Smart Farming Technology (SFT) encompasses Farm Management Information Systems, Precision Agriculture and Agriculture automation and robotics. Smart AKIS will collect existing knowledge related to SFT and will produce easily accessible end-user material under the EIP-Agri common format. The project will also integrate the socio-economic aspects involved in the innovation processes and will generate interactive and innovation-based collaborations among researchers, advisors and farmers through the use of open innovation in multi-actor workshops. Knowledge flow will be facilitated through the implementation of the Smart Farming Community Platform, which will be compatible with the EIP-SP in order to ensure long term accessibility of results.Smart-AKIS will build on results from five flagship EU projects (VALERIE, SOLINSA, PRO-AKIS, FRACTALS, AGRISPIN), through the participation in the project of their core partne
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Molecular mechanisms of circadian gating interconnecting light and clock signaling in Arabidopsis'.

assistant: **Innovation**

The periodic succession of days and nights is an eternally recurring environmental factor ever since life has appeared on the Earth. It is postulated that (i) organisms possessing the ability to adapt to the predictable changes of the environment have an evolutionary advantage and that (ii) this benefit has promoted the development of timekeeping mechanisms (endogenous clocks). The biological clocks that generate and maintain oscillations of many physiological and molecular processes with a period length close to 24 h are also referred to as circadian clocks. In a canonical circadian system, the central oscillator generates an oscillation with a period of -24 h, and regulates overt rhythms through the output pathway. Light signals absorbed by photoreceptors reach the central oscillator through the input pathway and reset its phase to the periodic environmental changes. The oscillator feeds back to the activity of the light input through rhythmic gating of light input components. Due to the intimate
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'High-performance data-centric stack for big data applications and operations' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The new data-driven industrial revolution highlights the need for big data technologies to unlock the potential in various application domains. To this end, BigDataStack delivers a complete high-performant stack of technologies addressing the emerging needs of data operations and applications. The stack is based on a frontrunner infrastructure management system that drives decisions according to data aspects thus being fully scalable, runtime adaptable and performant for big data operations and data-intensive applications.BigDataStack promotes automation and quality and ensures that the provided data are meaningful, of value and fit-for-purpose through its Data as a Service offering that addresses the complete data path with approaches for data cleaning, modelling, semantic interoperability, and distributed storage. BigDataStack introduces a pioneering technique for seamless analytics which analyses data in a holistic fashion across multiple data stores and locations, handling analytics on both data in flight and at rest. Complemented with an innovative CEP running in federated environments for real-time cross-stream processing, predictive algorithms and process mining, BigDataStack offers a complete suite for big data analytics. BigDataStack holistic solution incorporates approaches for data-focused application analysis and dimensioning, and process modelling towards increased performance, agility and efficiency. A toolkit allowing the specification of analytics tasks in a declarative way, their integration in the data path, as well as an adaptive visualization environment, realize BigDataStack’s vision of openness and extensibility.With an emphasis on standardisation and open source contributions targeting high impact, BigDataStack will enable data operations and data
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Many Diasporas from One Transnational Italy'.

assistant: **Concept**

TransIT is inspired by the necessity of promoting a more open and complex perception of Italian culture in the context of higher education. It aims to broaden the conception of Italianness by investigating a series of cultural texts that can be included within a comprehensive definition of ‘Italian culture’, once this is extended to its migratory and diasporic manifestations. Since Italy’s unification, migration has affected a significant part of the population, who started leaving the country in search of better living conditions. Excluding from the study of Italian culture texts produced in the context of Italian migrations, whether written in Italian or not, thus implies the exclusion of a significant part of this culture. On these premises, TransIT draws upon multidisciplinary resources – literature, film, television, newspapers and magazines, sociological surveys and historical documents – and adopts an interdisciplinary approach to examining the evolution of Italian culture outside of Italy, with a specific focus on the experiences included within the Italophone and Anglophone worlds.  In looking at race- and gender-specific cultural witnesses, it seeks to redress the mainstream interpretation of Italian culture.Engaging with universities in the United Kingdom and the United States, the project responds to the demand for revised and updated methods and materials for teaching Italian culture in transnational perspective. TransIT offers a novel set of teaching resources, moving beyond the conventional textbook and promoting an innovative and multi-layered methodology which encourages a dynamic approach to textual analysis. An interactive, bilingual online multimedia anthology of creative texts constitutes its principal outcome. Its bilingual nature makes much of thi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Deciphering post-translational control of Argonautes and their effects on small RNA homeostasis (PASRNA)' under Seventh Framework.

assistant: **Concept**

Argonaute (AGO) proteins are integral components of most small RNA silencing pathways in plants and metazoans. Previous studies in both model systems have demonstrated an inherent link between AGO levels and the steady state expression of global populations of miRNAs, strongly suggesting a layer of homeostatic control. In an effort to understand this phenomenon, we have set out on, a series of experimental approaches to uncover and characterise the mechanisms underlying AGO post-transcriptional control. Under normal physiological conditions, and in response to viral infection, we will monitor how the turnover and activity of AGO impacts the global small RNA equilibrium in both plants and metazoans.  We have identified a potentially conserved mechanism, whereby Cullin RING-E3 ubiquitin Ligases (CRL) negatively regulate AGOs functioning in miRNA-mediated gene repression.  Employing both plant and mammalian models systems in a multidisciplinary approach, we aim to dissect the role of CRLs’ activity on small RNA pathways and AGO1 biology, using a range of biochemical, genetic and molecular biology techniques.  In addition, we will employ a proteomic-based screen to identify the full degree of AGOs post-translational modifications. Collectively these approaches should unravel novel modes of AGO regulation through the control of subcellular localisation, protein-protein interactions or RISC assembly/recycling. Overall, the proposed systematic investigation of the currently elusive mechanism(s) underlying AGO regulation and small RNA homeostasis will provide greater insights into fundamental aspects of small RNA biology. This is pivotal to further our knowledge regarding the therapeutic, veterinary and agronomical exploitation of these molecules.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Integrated Photonic Field-Effect Technology for bio-sensing functional components'.

assistant: **Innovation**

The objective of this project is to develop a miniaturized cheap and disposable photonic device for bio sensing that is capable of performing quantitative diagnostic tests that are currently limited to a hospital laboratory setting. Our target product is a disposable device for monitoring cardiovascular health - an EU-wide healthcare priority. To date Microfluidic (or Lab-on-a-Chip) devices have not been well suited to point-of-care applications. Although the chips themselves are cheap and small, they must generally be used in conjunction with bulky optical light-sources and detectors. The lack of an integrated, versatile detection scheme is a major obstacle to the deployment of portable diagnostic devices. Consortium partners have demonstrated that integration of organic diodes and photodetectors is a viable route to meet this need. The purpose of this proposal is to develop a radically new generation of devices, in which organic photonic field-effect transistors are used for both light generation and detection. The use of transistors in place of diodes has four principle benefits. Firstly they can be pre-fabricated on the substrate (the microfluidic chip), ensuring optimal registration between the organic photonic components and the underlying fluidic architecture. Secondly the devices can be completed by depositing a single layer of organic semiconductor followed by the gate electrode, thus avoiding the need for complex multilayered structures. Thirdly in-plane light generation by the transistors provides improved optical coupling into wave-guiding structures, leading to significant performance gains. And fourthly current-multiplying auxiliary transistors can also be included thereby enabling immediate amplification of the signal at the point-of-generation. In combin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Catalysis toward platinum substrates for drug delivery'.

assistant: **Concept**

Flavins can act as efficient photocatalysts for the conversion of Pt(IV) complexes into Pt(II) anticancer drugs such as cisplatin and carboplatin (Chem. Sci., 2017, 8, 4619; Angew. Chem. Int. Ed., 2018, 57, 3143; ACS Catal., 2020, 10, 187). These unconventional catalytic reactions are bioorthogonal. Thus, they occur with high selectivity in biological environments, with minimal off target reactions. Nevertheless, advancing the application of this original chemistry in chemotherapy requires an optimal co-localization of the flavin catalyst and Pt(IV) substrate in cells or tissues in order to control the release of active Pt(II) drugs upon photocatalytic activation. To this end, DELCAT proposes the covalent entrapment of Pt(IV) anticancer complexes and flavins, such as riboflavin and its functionalized derivatives, into biocompatible agarose (AG) and polyglycerol (PG) hydrogels. The functionalization versatility of these polymers is ideal for the development of drug delivery platforms that could display various loading capacities, pharmacokinetics and drug release profiles. Hence, the project will engineer AG and PG hydrogels of different structure for loading flavins and Pt(IV) prodrugs, and then assess the drug delivery capacity of these materials in skin tissues. Ultimately, the project will provide innovative photocatalytic polymeric biomaterials for the efficient administration of platinum-based anticancer drugs.


**Keywords:** Transition metals, Medicinal Chemistry, Biomaterials
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Stone-working across the ancient Mediterranean. Building techniques, artisans and cultural identities: a view from North Africa""' (SWORM).

assistant: **Concept**

The proposed research concerns a multi-disciplinary study of stone-working techniques in the ancient Mediterranean starting from an archaeological analysis of built structures. In particular it focuses on the so-called opus Africanum, a group of masonry techniques characterised by vertical frameworks of stone blocks. It arrived in North Africa as a consequence of the Phoenician colonisation, and thereafter spread through the Mediterranean basin, especially to Italy, Spain and France. Its attestations from the late Punic age (2nd c. BC) until the end of the Roman period (5th c. AD) will be analysed with the objectives of understanding how ancient technology spread in the ancient world, what were the political and socio-economical conditions that allowed its diffusion as well as the role of artisans and patrons, and how we can extract information on their cultural identity through building techniques. The Applicant proposes to carry out a two-year research period at the UMR 8546 of the Ecole Normale Supérieure in Paris, where a team working on the Archaeology of Construction is leaded by the Applicant’s supervisor. Combined with the Applicant’s own experience, this will allow the further development of a new methodological approach for studying ancient architecture and for integrating archaeology, anthropology, geology, and seismology. A database on building techniques will be developed together with custom-made free software to obtain 3D realistic models of ancient monuments based on digital pictures, from which points-clouds with RGB values can be processed. This project will be of mutual benefit for the Applicant and the Host organisation, and will enhance EU scientific excellence through new agreements with North African institutions for new fieldwork projects. Dissem