RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Polyurethane foams from renewable raw materials' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

One of the crucial issues of our time is energy conservation, an important sphere of it being heat and cold conservation, or thermo insulation. Thermo insulation is of importance in construction, district heating, chemical storage and synthesis reactors. Different materials are used for thermo insulation; the most efficient material with the smallest heat conduction coefficient being foam polyurethane. Nowadays, the principal raw materials used for the production of polyurethane chemicals (including foam polyurethane) are products of oil chemistry. But oil reserves are decreasing and, consequently, the prices of fuel and also chemical raw materials are increasing. Due to reduce in oil reserves, raw materials can become extinct at all. A part of the raw materials, needed for the production of polyurethane, can be obtained from renewable materials, i.e. from the wood and plant origin raw materials.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Pervasive Ubiquitous Lightwave SEnsor' to be submitted under Horizon 2020.

assistant: **Abstract**

PULSe's objective is to optimize, industrialize and create the conditions for a market exploitation of the first cost -effective Brillouin distributed sensing solution based on a synergy of innovations on interrogator equipment, strain sensing cable and open-access application support tools.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'High Quality Solanaceous Crops for Consumers, Processors and Producers by Exploration of Natural Biodiversity' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

EU-SOL is a network of plant scientists from universities, research institutes and industry within the EU, Israel and INCO countries that focuses on the development of high quality and healthy tomato and potato varieties with improved consumer-, processor- and producer-directed traits. Quality and wholesomeness of food and food products are two issues addressed prominently by society especially in relation to obesity (and atherosclerosis), the most important cause of cardiovascular disease, age-related dise ases, such as cancer and diabetes and to the increasing preference of consumers for ???regional??? and ???niche??? food specialties. Additionally producers are challenged by environmental constraints such as diminishing fresh water supplies and climate cha nge that undermine stability of production. The strategic objectives of EU-SOL are to understand the factors that affect consumer-driven and environmentally-directed quality of the two most important vegetable products in the EU, tomato fruits and potato tubers, both belonging to the Solanaceae. To this end, EU-SOL will attempt to dissect the genetic and molecular components that control these quality traits by applying state-of-the-art knowledge and technologies. EU-SOL particularly focuses on mapping, is olation and characterization of genes responsible for traits important for consumers and processors (health, nutrition, flavour, fragrance, soluble solids, texture, colour, shelf-life) as well as for producers (abiotic stress: cold, heat, drought, salt), a nd the mechanisms underlying these traits (control of gene activity, regulatory networks). To accomplish these objectives EU-SOL will explore and exploit the natural biodiversity related to these quality traits that are largely unexplored and hardly used i n cu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Investigating the crosstalk between Notch and YAP/TAZ in sprouting angiogenesis' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Our limited understanding of angiogenesis, the process leading to the formation of new blood vessels from pre-existing ones, hinders the design of new treatments for associated diseases such as cancer, ischemia, and diabetic retinopathy. It is well established that sprouting angiogenesis involves a process of endothelial cell phenotype selection mediated by the interaction between vascular endothelial growth factor (VEGF) and Notch signalling. Recently, it has been demonstrated that the Yes-associated protein (YAP) and the transcriptional coactivator with a PDZ-binding domain (TAZ), the main mediators of the Hippo signalling pathway, interact with VEGF and influence Notch signalling. However, it is still unclear how the effects of YAP/TAZ on Notch signalling contribute in regulating angiogenesis. In this project, I will adopt an approach combining experimental and computational techniques. First, I will culture endothelial cell monolayers on differently stiff substrates and I will perturb Notch via ligand-coated beads and YAP/TAZ activity via pharmacological inhibition. With the information deriving from these experiments, I will develop a unique agent-based computational model for angiogenesis, accounting for the interplay between Notch and YAP/TAZ. I will use this model to predict the effects of the Notch-YAP/TAZ crosstalk on angiogenesis. Finally, I will adapt previously established in vitro experimental systems recapitulating angiogenesis in three-dimensional environments. In these systems, I will vary the matrix stiffness, inhibit YAP/TAZ activation, perturb Notch signalling with ligand-coated beads, and measure the changes to parameters such as sprout and branch density and the dynamics of individual cell behaviour.  This interplay between experimental and computa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Legonucleotides for detection'.

assistant: **Innovation**

Sensors have a vital importance on human life, detecting diseases or contaminants that endanger the environment. A widely pursued challenge has been to develop universal biosensors with the flexibility to detect molecules regardless of their size. Antibodies have been used to fulfill this aim, but single-stranded oligonucleotides (aptamers) interact efficiently with targets and have also been proposed as an alternative. However, aptamers lack the ability for versatile functionalization to tune affinities, and they suffer from highly complex selection and identification. Chem2Sense proposes an interdisciplinary approach to overcome these obstacles. My hypothesis is that a new strategy based on the reversible conjugation of aptamers with small molecules will remove barriers in designing universal biosensors. Chem2Sense aims to redesign the aptamer concept with flexible oligolegonucleotides and a cutting-edge nanopore sequencing methodology. The two objectives will be to develop chemically modified nucleotides as lego-bricks to build high-affinity aptalegomers, and to develop a ground-breaking sequencing methodology using artificial intelligence to boost aptalegomer identification. The proposed legonucleotides are synthetic nucleotides that reversibly attach small molecules in a dynamic combinatorial library. After challenging a vast library against a target, a Darwinian chemical selection will occur, leading to the best fit, the aptalegomer, a high-affinity oligonucleotide of natural and conjugated legonucleotides.Therefore, the objective of Chem2Sense is to create a ground-breaking methodology that overcomes significant obstacles in aptamers’ development, providing a powerful synergy between novel chemical aptalegomers generation and a direct method for selection/identif
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Centres of excellence for industrial gas turbines' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

The aim of this project is to co-ordinate the research activities and the knowledge and experience in gas turbine industry, universities and research institutions. Additionally the efforts shall be focused on the dominant problems in industrial gas turbines to be solved.Objectives of this project are to:-Create a Centre of Excellence that will act as a platform for a European research area related to industrial gas turbine technology.-Define the future technology demonstration requirements of the European industrial gas turbine industry and to co-ordinate and prepare in cluster, European projects in the defined areas.-Define and co-ordinate research activities related to the industrial gas turbine industry in Europe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Development of new strategies for osteochondral regeneration'.

assistant: **Objectives**

In contrast to any conventional therapies, regeneration medicine such as tissue engineering requires highly cross-disciplinary knowledge and technology. In this proposal, we propose new strategies for tissue engineering osteochondral tissue to tackle a disease caused by physical trauma and age-related degeneration, a major health problem in western societies. Despite various therapeutic options, no optimal solution has been found for the treatment of cartilage and osteochondral defects. This project aims to develop a new type of osteochondral scaffold to stimulate chondrocytes and osteoblasts growing in a monolithic structure with different architecture regions. The frame of the scaffold will be constructed by degradable PLA/PCL blends with tailorable degradation mechanisms. The collage II and hyaluronan gel will be incorporated into the large pore region by plastic compression to enhance chondrogenesis, whilst HA and TRAP signalling components will be adhered to small pore region to promote bone formation. To accelerate the maturation of the tissue and matrix production, external mechanical stimulation to the constructs will be applied. The feature of the various pore architecture through the scaffold enables transfer of differentiated strain to the seeded cells depending on the area where the cells are present under a single load regime. This multidisciplinary project will be hosted by one of EU excellent institute within NoE network in tissue engineering. The research fellow has accepted comprehensive training in materials science in a top ranked university in Turkey. The complementary expertise and experience between the fellow and the host ensure the success of the proposal. The success of the project shall share the knowledge and technology between the fellow and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Ecogenomics of Mosquito-Microbe Symbiosis for Novel Control Strategies of Infectious Diseases'.

assistant: **Concept**

The burden of mosquito-transmitted diseases such as Plasmodium, Dengue, West Nile, Zika, Usutu, or yellow fever continue to increase globally, representing one of the most significant public health threats. In the context of insecticide resistance concomitant to the absence of an efficient vaccine, new strategies that focus on mosquito’s microbiota are being developed. In particular the widespread intracellular bacterium Wolbachia, which can limit pathogen transmission and hijack host reproduction, represents one of the most promising tools to control the transmission of disease. Nevertheless, the genomic variability of Wolbachia and its mobilome, together with its influence on pathogen blocking, in interaction with other symbiotic Life in naturally infected vectors, remains largely unknown. In this project, I plan to dissect the mechanisms of interaction between Wolbachia, commensal (“healthy”) bacterial communities and pathogens, using cutting-edge ‘omics’ and molecular approaches.1.Wolbachia variants: I will use shotgun metagenomes to reconstruct Wolbachia and other symbiotic genomes and investigate the links between Wolbachia genetic variability, density and protection in naturally infected individuals at the organ level. I will explore the extent and potential role of Wolbachia phages in mutualistic traits such as defense through differential expression analyses in native conditions and controlled infection within Culex spp. 2.Midgut microbiota: I will explore the diversity, variability, role, and interaction of midgut symbionts with arboviruses through 16S amplicon sequencing and expression analyses in experimental infections conditions in Culex spp. 3.pWCP: I will investigate the transformation and expression capacity of the first and newly discovered Wolbachia p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Professional tool to facilitate data collection and digitalization in field trials for plant breeding and seed commercialisation'.

assistant: **Objectives**

We are a highly innovative company founded in 2013 for the development and marketing of a computerized and internet operated advanced decision support system for breeding. Based on our knowledge of the needs of the plant breeding sector we have designed BreedIT-Field a software tool for collecting plant phenotypes in the field which makes use of the latest ICT technology (computer vision, QR code scanning) to facilitate data collection, digitalization and analysis from breeding field trials and seed production fields. The main advantages of Breedit-Field are the following: -It will reduce time to market, by optimizing planning, management and execution of growing trials -It will reduce the overall costs of field trials up to 35% of breeding programs, by accelerating field inspections, eliminating costly errors, by optimising operators´ work and by reducing the administrative workload by the automatic generation of daily field books -It will facilitate communication and collaboration between research groups, field evaluation teams and production units across multiple locations worldwide optimizing breeding and seed production process. The development of Breedit-Field is of vital strategic importance for our company because it will open new business opportunities in line with our current know how and will boost our growth giving us a consolidated position at international level.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Renewable materials and healthy environments research and innovation centre of excellence (InnoRenew CoE)' (2014-2020).

assistant: **Concept**

With excellence in research, innovation, and application into economy and society, the new Centre of Excellence, Renewable materials and healthy environments research and innovation centre of excellence (InnoRenew CoE) will improve sustainable building practices by combining the existing concepts with the Restorative Environmental Design (RED) paradigm, which combines sustainable building practices with biophilic design. This will increase the competitive advantages of the affiliated renewable resource-based construction industry, and create innovation and market pull for RED-based materials and products (holistic living environment). Consequently, innovation and market pull for material recovery and higher added value renewable resource based and energy carriers will be initiated. Research and development activities will seek the optimal intersection of performance and sustainability, including economic, environmental and societal indicators. With support and guidance from the advanced partner, Fraunhofer WKI, scientific research and development activities will be transferred profitably and efficiently to the industry and through them to society in the form of innovative new products and processes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Enable power technologies on 300mm wafer diameter', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

EPT 300 aims to be a decisive step forward to strengthen Europe’s leading position in power semiconductor technologies and More-than-Moore manufacturing capabilities relating to energy efficient electronic solutions. Power semiconductor devices fabricated in a European leading pilot line for 300mm wafer production are the scope of the project, for which manufacturing excellence, cost competitiveness and challenging applications are critical boundary conditions.The project will thus address challenges in the research on process technologies, production technologies and handling and automation for advanced power technologies based on 300mm wafers:• Wafer substrate materials for 300mm diameter thin wafers for power applications• New process capabilities and technology approaches • Enabling of processing equipment with capabilities specially derived from the requirements of manufacturing power devices on thin 300mm wafers• Handling and automation concepts for thin wafer and special requirements of More-than-Moore fabrication lines• Coexistence strategies for integrated multi-wafer-diameter manufacturing• Application requirements for demonstrator application and corresponding quality requirement profilesWith the intended research it is planned to achieve the realization of demonstrators in a pilot line and to demonstrate the readiness for production in large scale production environment based on selected products and technologies. The demonstrator will be verified in a fully functional energy efficient power application. By this project, the base toward future enhancements in power technologies will be made.With the help of EPT300, the European semiconductor manufacturing and the European equipment & materials industries will be the worldwide first with a 300mm power semicon
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'The dynamics of metaphors in the communication of biotechnology'.

assistant: **Innovation**

In Europe, medical biotechnology is constantly metaphorised as breakthroughs" that reveal 'the secrets of life" while agricultural biotechnology is often labeled as "Frankenfoods ". These metaphors are circulated in the mass media, but also in the sciences, politics, economics, administration and every day conversations. Metaphors guide the dynamics of communications, and therefore metaphor analysis provides tools for understanding the complexity of communications, and to clarify the grounds on which current and future European debates on biotechnology can be established. The project analyses the European discussions about medical and agricultural biotechnology both quantitatively and qualitatively from a dynamic perspective, and uses metaphors as analytical tools of tracing the mechanisms communication between scientific, social scientific, public, and journalistic discourses. The data is collected from the Internet, Science Citation Index, Social Sciences Citation Index and on-line archives of four European newspapers. The research question is : "How do metaphors enable us to bridge the gap between the sciences and the social sciences as well as between the sciences and the public?""