RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The emergence of distinct emotions in human development' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Emotions drive our behaviours and help us navigate our physical and social worlds. While a broad range of distinct emotions have recently received attention in studies among adults, comparable research among young children remains scarce. We thus know next to nothing about   when, how, and why emotions such as awe, excitement, and envy emerge in early development, limiting our understanding of how emotions motivate and guide young children’s everyday behaviour. This pioneering interdisciplinary research program on the emergence of distinct emotions in early development aims to systematically study 12 distinct emotions—interest, excitement, awe, feeling moved, schadenfreude, elevation, confusion, worry, disappointment, envy, resentment, and indignation—in children from nine months to five years. The central premises are that (1) we need to study different components of emotions: their elicitors, nonverbal expressions, physiological reactions, and effects on subsequent behaviours, as well as prerequisites and individual and social mechanisms of development; and (2) this research should be conducted in naturalistic contexts.Integrating qualitative approaches with ethological, experimental, longitudinal, and cross-cultural designs, I will empirically investigate when, how, and why distinct emotions emerge in early development. The first objective is to observe different components of emotions as they naturally occur in everyday life across cultures. The second objective is to experimentally examine the causes and consequences of the 12 emotions. The third objective is to map the timing, (socio-)cognitive prerequisites, and the individual and social mechanisms that give rise to these emotions. The overall ambition is to advance the first integrative and empirically grounded
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'INNOVATIVE TECHNOLOGY FOR RAPID AND DURABLE ASPHALT ROAD REPAIRS'.

assistant: **Innovation**

The overall objective of the project RADARR (RAPID AND DURABLE ASPHALT ROAD REPAIRS) is to verify technological and economic feasibility of innovative technology for asphalt surface repairs using microwave technology and absorbing agent. The novelty of the technology lies in a completely new approach in pavement repair offering great advantages for various customers. Microwave technology represents a revolution in asphalt road maintenance. It enables durable repair results, faster application and it is simple, more effective and economic in comparison with currently applied technologies. Application of the microwave technology enables elimination of non-homogenous connection of repaired spot resulting in significant extension of life span of repairs. Extended life span of repairs means great savings for infrastructure owners and operators and thus it means great market opportunity for FUTTEC Corporation. Outcome of the project RADARR will be a feasibility study and a business plan for commercialization of the asphalt repair microwave technology that will bring functional versatile device using the microwave energy for repairs of cracks in asphalt surfaces (potholes) and to connect technological joints of new or repaired asphalt surfaces suing polymerisation agent. The feasibility study and business plan will bring realistic estimation of market size, market growth potential, organizational requirements, assessment of competitive solution and other necessary aspects. Complex and sound feasibility study and business plan will help reach the overall commercialization goal and attract potential investors.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'The role of the Earth’s mycelial community and enzyme activity on global atmospheric CO2 and COS budgets'.

assistant: **Innovation**

The recent activity of humans has had such a profound impact on the chemistry of the Earth’s atmosphere that ecosystems and societies face a ‘human-induced’ climate crisis. Given the key role of the biosphere in climate change feedbacks, the Paris Agreement emphasised every effort should now be taken to ensure ecosystems are managed to reduce the growth rate of atmospheric CO2 without altering climate. However, Land Surface Models (LSM) still lack consensus on critical processes driving the exchange of CO2 between ecosystems and the atmosphere. Variations in atmospheric carbonyl sulphide (COS) could provide independent constraints on LSM performance at large scales and evidence for the recent ‘CO2 fertilisation’ effect on the biosphere. Free-Air CO2 Enrichment (FACE) studies also reveal that, as CO2 rises, trees forming symbiotic relationships with ectomycorrhizal (EM) fungi may accumulate biomass more readily than trees in symbiosis with arbuscular mycorrhizal (AM) fungi, especially in nutrient-poor soils. So far, incorporating EM and AM functional traits into LSMs remains a challenge. Representing key differences in AM and EM plant root and fungal processes in LSMs such as the secretion of acids and enzymes into the soil will be necessary, as they augment organic matter mineralisation and soil weathering, impacting atmospheric CO2, and potentially COS budgets. Because EM plants tend to grow on acidic soils, EM fungi should express more carbonic anhydrase (CA) an enzyme that helps regulate their internal pH, with repercussions on COS fluxes. As nitrogen availability inhibits CA activity this may help explain why the growth of EM plants is reduced in acid environments. COSMYCA will quantify EM and AM fungal CA activity for the first time and characterise mechanistically
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Identification and characterisation of novel cell-fate influencing genes in pre-implantation mouse development' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Just prior to uterus implantation mammalian blastocyst stage embryos have already started the process of generating and segregating different cell types required for continued development. Exactly how this remarkable transformation from a single fertilised egg to a highly ordered multi-cellular blastocyst occurs, within just a few days, remains a fascinating and enduring question. During this time embryonic cells either start to adopt specialised functions (differentiate) or they can remain in a so-called ‘pluripotent’ state, only differentiating later in development. Understanding the mechanisms behind such in vivo ‘cell-fate decisions’ is fundamentally important but can also provide insight into the proposed future application of stem cell based regenerative therapies. Research on mouse embryos has begun to address these cell-fate related issues and has highlighted the importance of tight temporal control of specific gene expression and the impact of relative cell position (i.e. on the outside of, or encapsulated within the embryo) to blastocyst formation. Herein, we propose to identify, verify and thoroughly characterise novel early mouse embryo cell-fate influencing genes. Candidate genes have already been identified by integrating our unpublished experimental data aimed at uncovering genes differentially expressed in outer and inner cells with pre-existing datasets describing gene expression throughout the whole of early development. Accordingly, we plan to disrupt the expression of these candidate genes within discreet cell populations of the developing mouse embryo and to observe whether this will affect their ultimate cell-fate. If so, we will determine how this impacts upon already known cell-fate related genes and mechanisms of cell segregation. We will also i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Post-graduate training network for capacity building to control ticks and tick-borne diseases' under Seventh Framework.

assistant: **Concept**

In the context of global warming and globalisation, tick and tick-borne diseases (TTBD) are expected to emerge, with an increasing risk for animals and humans. It is imperative therefore to build up training capacities to improve integrated control measures, including the development of efficient and appropriate vaccines. The POSTICK ITN aims to (1) design new effective control strategies for TTBD diseases through understanding the mechanisms of tick-host-pathogen interactions regarding (i) pathogen diversity, survival and transmission, modulation of host immune response and tick survival and (ii) identification of host-pathogen-tick molecules for designing anti-tick vaccine and blocking pathogen transmission; (2) improve career perspectives of early-stage researchers (ESRs), broadening research competences through a strategic training programme consisting of (i) Research Training Packages including 14 individual PhD research projects and (ii) Complementary Training Modules including seminars, workshops, symposiums and a conference, combining the facilities and complementary expertise of 5 universities, 1 research institute and 2 industrial participants from 5 European countries and of 2 associated partners from Brazil and Israel. This ITN will be coordinated by the Ludwig-Maximilians-University, Germany, with a management structure including a steering committee and a supervisory board. The impact of the ITN lies on (i) a complementary research programme covering different areas of tick-pathogen-host interaction, (ii) an innovative training programme of high quality, (iii) improvement of existing collaborations between industry and research centre and universities, (iv) enhancement of the career prospects of ESRs, (v) contributing to European Community policies regardi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Manufacturing and Production Equipment and Systems for Polymer and Printed Electronics' (PRODI).

assistant: **Innovation**

The intention of the Coordination Action Manufacturing and Production Equipment and Systems for Polymer and Printed Electronics" (PRODI) is to integrate European printing, coating, and other advanced processing machinery manufacturers, production line integrators, and process measurement and automation industry to work together to improve European excellence and competitiveness in roll-to-roll (R2R) Polymer and Printed Electronics manufacturing equipment and production lines business. The objectives of the project include collecting the requirements for the new manufacturing machinery, measurements and automation systems, and generating a common future vision for the industry on R2R polymer and printed electronics manufacturing equipment and production lines and systems. Intensive education and training program is organised by means of various workshops, training events and seminars for distribution of the state-of-the-art multidisciplinary technology information to the industry.  The active consortium consists of six core research partners, leading European research organisations in R2R polymer and printed electronics, and an invited industrial advisory board (10-15 members), a selected group of leading companies in the areas of printing machinery, coating, laser, embossing/imprinting, measurement and instrumentation, automation, and production line integration, to be the industrial reference, actively contributing, advising and supervising body within the project. For the broader networking and exploitation an associate network (approx. 100 members) will be formed consisting of parties interested in monitoring the developments and future business opportunities of R2R polymer and printed electronics, and especially manufacturing equipment and production systems."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Sustainable Materials for Innovative, Low Emissions applications in the CIrcular ciTY' (2021-2027) under Horizon Europe.

assistant: **Objectives**

SMILE CITY provides realistic circular systemic solutions to support the evolution towards a carbon-neutral, environmentally sustainable, toxic-free, circular economy by 2050. The contribution to C02 reduction works on two levels:- an intensive use of recycled materials in replacement of virgin ones, without decreasing the performance of final products;- the use of such products and applications to increase sustainable mobility.The project aims to integrate innovative systemic solutions in up to 100 km of cycling paths and implement 20 e-bike charging stations, developed using different types of recycled urban waste: construction materials, EoL tyres and EoL batteries from Electric Vehicles. The foreseen innovations include the creation of e-bike charging stations made of recycled concrete precast elements and PV panels equally produced with recycled materials, the installation of recycled rubber moulded products for urban furniture such as rubber bollard, lane dividers, and rubberized asphalt, which contributes both to increase sustainability and safety.SMILE CITY will thus assemble the technological state of the art of the different value chains involved to implement circular systemic solutions in 7 different EU and non-EU countries, backing the transition towards a regenerative, inclusive and circular economy at local and regional scale across Europe and therefore boosting interregional and cross-border cooperation.In addition, the project will also increase resource efficiency, reinforcing Europe’s strategic autonomy and reduce the negative environmental footprint related to current recycling techniques of the considered urban waste value chains. By supporting awareness raising and information spreading, SMILE CITY will engage both citizens and industrial leaders in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Vaccine for prevention and treatment of Trypanosoma cruzi infection' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Chagas is a neglected disease endemic in 21 Latin-American countries caused by Trypanosoma cruzi. It is the largest parasitic disease burden in the Americas (>11,000,000 chronic infections) and the first cause of cardiac morbidity in poor rural/suburban areas. It became a worldwide concern as a result of mass migration with reports in 19 non-endemic areas (>1.3 million carriers in EU/USA). Treatment is difficult since acute infections have mild symptoms and remain largely unnoticed evolving to chronicity. Drug therapy is also long, often associated with side effects (10-30% interruption) and only active during early infection. The main objective of CRUZIVAX is to bridge the gap between preclinical and clinical development by performing preclinical and clinical phase 1 studies of a needle-free vaccine against T. cruzi with proven efficacy in preclinical models. The vaccine is based on a structure-engineered trivalent chimeric antigen lacking immune decoy sequences and an adjuvant promoting self-limited locally-restricted immune activation stimulating humoral and cellular immunity, which is expected to protect as prophylactic or therapeutic (combined with Benznidazole) vaccine. To achieve this CRUZIVAX will: (i) conduct preclinical studies in mice to assess immunogenicity and efficacy of different vaccine formulations in prophylactic and therapeutic settings, (ii) analyse the immunogenicity and efficacy of the best vaccine formulation in dogs and non-human primates, (iii) produce cGMP antigen and adjuvant by cost-efficient manufacturing (facilitated uptake by health systems with limited resources), (iv) perform a preclinical safety assessment of the vaccine, (v) conduct a phase 1 vaccine clinical trial in healthy volunteers, and (vi) carry out a health economics analysis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Interdisciplinary practical summer courses on environmental risk assessment and advanced analytical techniques for contaminated and uncontamined matrices.' (1998-2002), addressing dissemination and exploitation.

assistant: **Impact**

The project is part of a 'Summer School trilogy' of the University of Bologna (Italy), the Technical University of Budapest (Hungary) and the University of Zurich (Switzerland). The three courses are completed in themselves but have common subjects and will be developed as follows:- The first year attendants will be in Ravenna, on analytical methods for freshwater, sea water and marine sediments to determine the availability of polluants in the studied areas of Ravenna Harbour and the Basin of Ridracoli;- The second year attendants will be trained in a mining region in Hungary, where heavy metals are extremely toxic, to carry out environmental impact assessment. Feasibility studies as well as environmental risk assessment;- The third year the attendants will be trained at the Institute of Environmental Sciences, University of Zurich and, at the Alpine Biology Centre in Switzerland, where especially microbiological-mediated processes within geochemical cycles are studied.These EuroLab courses are intended to be interdisciplinary events in full-equipped laboratories where zoological, botanical, microbiological, geochemical, chemical and social aspects are part of the content. EuroLabs aim at a high interaction between academia and industry and, the University of Ravenna will be supported for the local organisation by a multinational company (Montecani S.p.A) towards its Environmental Research centre, leader in soil bioremediation research, which will provide young researchers with a high level of training in the laboratories of chemistry, spectroscopy, chromatography, microbiology and pilot plants. This project has a strong scientific originality because the methods and hypotheses developed and applied in the Italian course (e.g. characterisation of marine and freshwater
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'ASSESSMENT OF DESALINATION MORTARS AND POULTICES FOR HISTORIC MASONRY' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

European cultural heritage is often damaged by salt related damaging processes. There appears to be an increasing risk of salt damage to our monuments, due to climate changes and possibly resulting floods. According to recent research, in some situations, desalination may be the only possible conservation technique. For buildings, desalination still constitutes a major problem as the bath-method can not be used. The use of desalination mortar/poultices seems to be the most promising conservation technique for immovable objects. However, the performance and especially the effectiveness of different desalination systems is not clear, which hinders the choice of an appropriate mortar/poultice.The research project DESALINATION will result in a clear guideline how to choose an adequate desalination system. This is of great importance to the European decision makers and will incorporated in a knowledge based decision tool.A second major result will be better knowledge of moisture and salt transport from the historic material to the desalination product. This knowledge will give raise to a recommendation for a test to assess the effectiveness of desalination products. The better understanding of the transport process may be used in product development and increases the competitiveness of European SMEs, and may have a much broader spin-off in all kind of salt related problems.