RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Large-scale, high-throughput automated systems for phenotyping mouse models of human disease'.

assistant: **Concept**

We are now entering an era of genomic exploration. The mouse is a pre-eminent model not only to map all mammalian genes, but to determine the function of each of these genes. There are now many large-scale projects to create collections of mutant and knock-out mice. However the next step which will add immense value to these collections will be the determination of the phenotype of each of these models. This will be an immense effort and will require input from laboratories and mouse phenotyping centres across the world. For the phenotype to be comparable across strains and between centres, it needs to be determined using standard protocols or SOPs, such as those contained in the European Mouse Phenotyping Resource of Standardised Screens (EMPReSS - www.empress.har.mrc.ac.uk). The goal of PhenoScale is to automate phenotyping in large-scale phenotyping using EMPReSS protocols; with the aim of adding economies of scale, enhancing automated data capture and increasing throughput. The technical development within the project is lead by the SME, TSE Systems GmbH, who will work with some of the leading mouse phenotyping centres in Europe at MRC, UK, CNR, Italy and GSF, Germany. The objectives are: 1) High-throughput Phenotyping: a) Development of a new high-throughput automated phenotyping platform PSS009 using home cage monitoring. 2) Development of new EMPReSS SOPs using PSS009 and validation of this approach with selected mouse models at different sites / European mouse clinics (cross-checking / cross-validation). 3) Optimization of the high-throughput technology systems by advanced interfacing and extended software capabilities. 4) Promotion of the new high-throughput systems and novel established SOPs to other phenotyping centres.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'In-Voyage Ballast Water Treatment System' under Horizon 2020.

assistant: **Concept**

ChallengeBallast water is the dominant vehicle for transport of invasive species in the marine environment, threatening ecoenvironmental stability and diversity. More than 7,000 different species are transported in the 3-10 billion cubic meters of ballast water, which are let over board each year, posing threats of extensive ecological and economic damage to the local aquatic ecosystems. The financial losses caused by these transported invasive species amount to more than €50bn per year in both the EU and US.Solution – the innovationBawat has developed a ballast water treatment system (BWTS) that eliminates invasive species in the ballast water tank using a new invention. The solution treats the ballast water in-voyage using excess heat from the vessel engines, thereby saving energy and costs.The treatment system runs automatically and independently of other on-board procedures and is 50% cheaper to operate for the ship owners than any competing system, and easier to fit in both existing and new vessels.ImpactThe project will have significant impact on both the operation of ships globally and the aquatic environments. The invasive species in the ballast water tank will be eliminated and never pose a threat to distant environments. Ship owners will save time and money when ships can leave the harbour right after loading/unloading, and money will be saved as excess heat from the engines is used to eliminate the biological activity in the ballast water tank.ProjectThe  objective is to secure a US Coast Guard type approval, as this approval is a de-facto “licence to operate” in the global market.Customers and marketThe customers are vessel owners and managing companies of vessels, with bulk carriers as well as oil and chemical tankers being the key end-users. Bawat estimate
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Ships as an adaptive and resilience strategy to wide-scale crisis in the Mediterranean (c.1550-700 BC): an open-access digital museum database integrating 3D modeling and virtual reality.' (ANCMED).

assistant: **Concept**

ANCMED will investigate the role of ships as an adaptive and resilience strategy in the face of wide-scale crisis in the Mediterranean during the Late Bronze and Early Iron Age periods. Its primary outcome will be the first of its kind open-access virtual museum that integrates a database on ancient ship depictions, digital photogrammetry, and VR presentation. As such, the project will address some of the most pressing challenges of the Digital Age, namely the insidious loss of knowledge on the ancient world due to various causes that include climate change, political instability, and the lack of publication and preservation of primary archaeological and cultural heritage data. Important research gaps will be tackled by: charting longue dure Mediterranean-wide patterns; a contextually informed approach to ship representations viewing them as cultural artefacts;  applying an innovative digital methodology that complements and enhances the archaeological analysis. Significant technical advances (performance, affordability, portability) coupled with a decade of experimentation (improved workflows, well-tested tools) have finally made my approach both timely and feasible. ANCMED is intended to become the principal online research tool on the topic of Mediterranean ships of the pre-classical period. Its broader impact will be to provide the framework and tools for scholars outside of the discipline to meaningfully use and integrate this dataset, to expand digital museum records and aid curators and conservators by providing a means to create cost-effective exact replicas. The project will develop and strengthen my profile as a multidisciplinary maritime archaeologist with expertise in the growing field of digital humanities. As an open-access virtual learning and public valo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Behaviour Phenotyping using Inertial Sensors', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Behavior is ultimately the observable output of the nervous system. Thus, to properly diagnose and monitor nervous system disorders it is crucial that we assess behavior comprehensively. However, every day clinical practice still relies mostly on subjective methods to evaluate behavior. The ability to adequately analyse behaviour is also critical during drug development, from the preclinical (animal models) to the clinical stages.  Results from our ERC-funded work revealed that the combination of inertial sensor data with an unsupervised algorithm provides an optimal method for an easy to implement unbiased behavior classification that adequately captured the outcome of neural circuit’s computations. In this PoC we proposed to develop this technology into a product that provides a continuous, quantitative and comprehensive behavior assessment that is also versatile,  covering the diverse spectrum from the pre-clinical to the clinical context. In this POC we will 1)  refinement and validate of inertial sensors in animal models, 2) enable their integration into a Body Area Network, 3) Evolve our unsupervised algorithm into a stand-alone software that is versatile and easy to use. In addition to these technical aims, we propose to explore commercial opportunities and societal benefits, in particular in the medical and drug development sector. We will conduct market analysis and develop a business case for this product, while expanding industry contacts for production and commercialization. Our proposal will lead to a ground-breaking technical solution for quantitative, automated behavioral assessment in animal models of disease and humans that will have an important societal impact through innovation in diagnosis, disease monitoring, and drug development.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Modular design and verification of executable specifications' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

Modular aspects of analysing, constructing and verifying executable specifications have received increasing attention in the last years, due to the enormous potential for significant advances in theory and practice. It is well-known that various basic properties and computation / reasoning techniques for executable specifications exhibit a non-modular behaviour in general, thereby impeding the design and verification of complex specifications by systematically combining simpler ones. In this project, the focus is on modular aspects of executable specifications in the framework of equational/rewriting logic, specification and programming. The objectives and envisaged research themes cover the following related fields. Firstly, several foundational issues of combining specifications will be investigated. This includes in particular the study of inheritence criteria for crucial properties of specifications under various practically relevant types of combination mechanisms. Secondly, important pragmatic and operational issues of analysing and constructing complex executable specifications, and of corresponding reasoning and proof techniques are studied. This will be done in connection with contributing improvements to the software systems ELAN (a logical framework based on the rewriting logic) and SPIKE (a theorem prover for first-order logic and inductive reasoning) developed by the PROTHEO team in Nancy. And thirdly, the previous theoretical and conceptual investigations on modular aspects of designing and verifying executable specifications will be applied to practical problems. In particular, it is intended to study specifications of telephone services, in the context of the cooperation between CNET France Telecom and PROTHEO.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Bi-Isotope 0n2b Next Generation Observatory' under Horizon 2020.

assistant: **Concept**

BINGO will set the grounds for a large-scale bolometric experiment searching for neutrinoless double beta decay with a background index of about 10-5 counts/(keV kg y) and with very high energy resolution – of the order of 1.5‰ – in the region of interest. These features will enable a search for lepton number violation with unprecedented sensitivity. The BINGO approach can lead to the demonstration of the Majorana nature of neutrino even in the unfavourable case of direct ordering of neutrino masses.BINGO is based on luminescent bolometers for the rejection of the dominant alpha surface background. It will focus on two extremely promising isotopes – 100Mo and 130Te – that have complementary merits and deserve to be both considered for future large-scale searches.The project will bring three original ingredients to the well-established technology of hybrid heat-light bolometers: i) the light-detector sensitivity will be increased by an order of magnitude thanks to Neganov-Luke amplification; (ii) a revolutionary detector assembly will reduce the total surface radioactivity contribution by at least one order of magnitude; (iii) for the first time in an array of macrobolometers, an internal active shield, based on ultrapure ZnWO4 scintillators with bolometric light readout, will suppress the external gamma background. These challenging technologies will be extensively tested in a two-isotope demonstrator, dubbed MINI‑BINGO, which will be located in an underground laboratory in a dedicated cryogenic infrastructure built with ERC funds.The BINGO approach can be implemented in the next-generation search CUPID, a proposed follow up of the CUORE experiment. BINGO can improve dramatically the sensitivity of CUPID, using two isotopes at the same time and providing the demonstrati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Nature Inspired Transition Metal Catalysis' to be submitted under Seventh Framework.

assistant: **Abstract**

The development of new approaches in transition metal catalysis is of utmost importance since it provides the future tools required to arrive at a sustainable society.  Interestingly, the field of transition metal catalysis has been dominated by the relatively simple dogma that the activity and the selectivity of the catalyst is determined by the interplay between the metal and the ligands that are coordinated to the metal. By developing new ligands, new catalyst can be uncovered that display specific reactivity and selectivity. Nature on the other hand, uses a much larger tool-box to arrive at catalytic systems that are generally far more active and selective than the man-made catalysts.  Enzymes often use multimetallic sites, or multi functional groups that work in concert. Importantly, Enzymes are much larger than synthetic catalysts, and take advantage of the second sphere around an active site by 1) creating a sterically constrained cavity around it leading to entatic states, i.e. deformed intermediate states that lead to lower energy barriers to the product 2) positioning functional groups within the cavity to properly orient and activate the substrate, by lower the transition state via secondary interactions.In the current proposal we control catalyst properties by encapsulation. Will will use isolated natural active sites (and models theirof) and install these in well-defined cavities and study their properties. Can we create a second coordination sphere such that we can get activities and selectivies similar to that of the original enzyme? For example, we aim for nitrogenase activity by putting isolated active sites in synthetic cages.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Functional Nano-Scaffolds for Regenerative Medicine' in the context of a Horizon Europe call.

assistant: **Objectives**

Repair or replacement of tissue and organ functions lost due to age, disease or damage represents one of the most urgent medical needs of our aging society. The NanoReMedi Consortium will contribute to addressing this fundamentally important issue by using a new and efficient scientific approach relying on the design, preparation, characterization and validation of conceptually innovative peptide-based functional nanomaterials for regenerative medicine applications. Specifically, NanoReMedi will tackle three highly relevant case studies: “Tissue engineered vascular grafts to replace damaged peripheral arteries”, “Stem-cell based regenerative medicine for bone and cartilage repair” and “Facing with implantation failure” this last addressed to overcome bacterial severe infections. As an equally important goal, the NanoReMedi Consortium aims to build a world-class doctoral educational model in the field of nanomaterials applied to regenerative nanomedicine, through a strategically designed Academia-Industry interplay. To this end, 6 Beneficiaries, one Associated Partner linked to a beneficiary and 12 non-academic associated partners will join their forces to: i)create a highly innovative research network for training a new generation of 13 Doctoral Candidates (DCs) with strong employment potential, aimed at studying and developing “Functional Nano-Scaffolds for Regenerative Medicine”; ii)establish a robust structure for long-term research cooperation between a pool of leading Universities and Enterprises, for broadening and strengthening the knowledge and skills of DCs accessing the nanoscience-area from adjacent disciplines (such as chemistry, material sciences and bioinformatics); iii)building a solid foundation for long-term European excellence in medical nanotechnology
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'A new joining process for assembly of integrated circuits on smart-cards using fast uv-curable anisotropically conductive adhesives' to be submitted under Fourth Framework.

assistant: **Abstract**

Today the joining process of integrated circuits (IC's) on the smart-card substrate is made with aluminium wire bonding or isotropic conductive adhesive joining. However, both these methods are not cost-effective. The wirebonding process requires a clean room facility and costly automatic bonding machines. Isotropic conductive adhesive joining requires, on the other hand, underfilling to obtain a strong and reliable joint. This is a time consuming process. Anisotropically conductive adhesive joining of IC's on smart-card substrates using fast UV- and heat curable conductive adhesives represents a new technology to obtain a low-cost and high speed joining technology. No underfilling operation is needed after the joining. The main objective of the project is to develop a new low-cost and reliable joining process of IC's on smart-card substrates using fast-curable anisotropically conductive adhesives. Photoinitiators will be used to initiate in-line cure before the IC placement and post cure off-line using heat and in dark cure in line after the IC placement. The goal is to reduce the production cost of the joined module by 50%. A vertical project group is planned consisting material, component, equipment and substrate supplier and end users. The partners come from Germany, The Netherlands, Finland, Switzerland and Sweden.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Terminology extraction, translation tools and comparable corpora'.

assistant: **Concept**

The TTC project (Terminology Extraction, Translation Tools and Comparable Corpora) aims at leveraging machine translation tools (MT tools), computer-assisted translation tools (CAT tools) and multilingual content management tools by automatically generating bilingual terminologies from comparable corpora in several European languages (i.e. English, French, German and Latvian), as well as in Chinese and Russian.Comparable corpora gather sets of texts corresponding to a same domain, but not necessary being a translation from each other.The main steps for automatically generating bilingual terminologies are the automatic extraction of monolingual terminologies and the bilingual alignment of the extracted terminologies. The terminologies will include single word terms (SWT) and multi-word terms (MWT), as well as their variations.The TTC project will develop generic methods and tools for automatic extraction of terminologies and alignment algorithms including adaptors to domains and languages, in order to break the lexical acquisition bottleneck in both statistical and rule-based machine translation. Alignment will be based on several strategies, i.e. lexical strategies (use of compositional methods and of an interlingua representation), contextual strategies (use of cognates, context vectors and labelled links) and corpora strategies (bettering of available corpora, for instance by topical web crawling). Developed methods will require as less prior linguistic knowledge as possible, so as to reduce the gaps in language coverage.It will also develop or adapt tools for gathering and managing these comparable corpora and for managing terminologies. In particular, a topical web crawler and an open terminology platform will be developed. This open terminology platform will suppor