RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Project management & engineering global control system' (PCS).

assistant: **Innovation**

Localisation of software is complex and presents difficulties in version control. Some software products include thousands of separate items (source code, bitmaps, etc.). This factor coupled with severe time pressure brought to bear by the client's requirement to ship the product and its localised versions simultaneously makes it increasingly difficult to avoid the difficulties caused by loss of version control.The main motivation for this PIE is to meet the following challenges with effective software configuration management:To reduce by 50% the incidence of incorrect configuration when versions of software products are released, avoiding the need for rework and thereby increasing customer satisfaction.To provide better control over the defect correction process, reducing by 50% instances of reported defects being missed or recurring after having been corrected.To allow control to be exercised over changes to products so that the complete change history for any component of any product version is available, showing who made each change, when it was made and why.THE EXPERIMENTThe stated objectives will be achieved through improvement of configuration and change management.Clockworks will define procedures for configuration management and defect correction at an early stage in the PIE, enlisting the aid of a human factors consultant. A tool or tools to support the procedures will be chosen that can support the complexity of version control in software localisation. The methodology used by Clockworks in software localisation will be modified dependent on the choice of configuration management tool. The chosen procedures, methodology, and tool will be used during the course of the baseline project in the localisation of a software package through all stages including eval
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Resampling procedures for assessing the fit of capture-recapture models' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Research objectives and content The project constitutes a key addition to recent methodological advances, which have enabled capture-recapture modelling to be undertaken using an analysis-of-variance approach. This approach involves first fitting an all-embracing 'umbrella model', which is then successively refined to provide a parsimonious description of the data. At present, however, this major methodological advance can founder due to the lack of reliable goodness-of-fit tests of the initial model. The project aims to develop resampling procedures to fill this gap. The first objective will be to provide bootstrap or Monte-Carlo based goodness-of-fit tests for the Cormack-Jolly-Seber family. These should be a major improvement on the existing asymptotic procedures. The second objective will be to extend these methods to encompass recently-developed multi-site models which are already being seen to be extremely useful in practice. Training content (objective, benefit and expected impact) Whilst working within the group at Montpellier I will be in an ideal position to extend my solid background in traditional capture-recapture methodology to cover both their analysis-of-variance approach and an increased range of applications of the material. The project will extend my experience of the resampling techniques in which my current University (St Andrews) has a leading position.  Links with industry / industrial relevance (22) NA
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'FISA 2025 – EURADWASTE’25  conferences on Euratom fission research and training'.

assistant: **Objectives**

The FISA-EURADWASTE event is a high-level, research policy conference on the outcomes and perspectives of the Euratom Research and Training Programme. This 11th edition of the conference will be held in Warsaw, Poland, in May 2025, under the auspices of the Polish Presidency of the Council of the EU. The organisers of this conference are: - the National Centre for Nuclear Research (NCBJ) the most important Polish research centre in the nuclear energy field, and the European Commission (DG-RTD). FISA’25 and EURADWASTE ‘25 conference objectives are: - to present progress and key achievements of the latest projects carried out since 2022 as part of the Euratom Programmes; - to stimulate discussions on the state of play of R&D, key challenges addressed at national, European and international levels on Research and Innovation policies, synergies and partnerships benefitting research and innovation programmes and future perspectives. Expected impacts, thanks to an ambitious communication and dissemination action plan, are: - increasing visibility of the Euratom research and training programme; - increasing awareness of nuclear research achievements; - networking EU stakeholders; - bringing new research project ideas and collaboration between different stakeholders; - orienting research, development and innovation orientations at the EU level; - increasing the visibility of national research potential and participation in the Euratom framework programme.


**Keywords:** Research Policy, Euratom, Polish EU Presidency, NCBJ, DG-RTD, FISA, EURADWASTE
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Bio-interfaces: From molecular understanding to application' under Sixth Framework.

assistant: **Concept**

BIOCONTROL aims at controlling biological functions at, respectively on, bio-interfaces. It is based on the recent recognition of the importance of structure and properties of bio-interfaces, e.g. biological membranes, for a multitude of life processes. We now know that the evolution of atherosclerosis, cancer, immunity and viral infections, neurodegenerative disorders (Alzheimer, Prion diseases, etc.) and aging depend on perturbations of such interfaces. However, we need to improve our knowledge of the underlying molecular mechanisms in order to design efficient drugs and to meet the challenges in regenerative medicine and tissue engineering. This requires a deeper understanding of processes and interactions at bio-interfaces in terms of biology, biochemistry, biophysics and structure.The two major scientific objectives of BIOCONTROL are to:1) Provide fundamental knowledge of the forces and molecular mechanisms that regulate the interactions and biological processes taking place in and around biological membranes.2) Construct bio-mimetic surfaces and self-assembled structures that enable external control of biological and biotechnological processes, such as, cell adhesion and cell cycle regulation.Real progress in the field can only be achieved by breaking traditional academic borders. This requires the education of new researchers that are trained in cross-disciplinary and collaborative work. Therefore the major educational objective of BIOCONTROL is: Training of a new category of 'life science' experts who can work across disciplines. This will be achieved by an unprecedented interdisciplinary training programme comprising (bio) physicists, biologists, (bio)chemists, surface chemists and computational biologists.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Institutional Frictions in International Finance and Asset Pricing', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

My project consists of three lines of work.1. Incentives of Money Managers and Asset PricingThe leading theories of asset pricing stipulate that prices in financial markets are determined by households who seek to optimise lifetime consumption (or by the so-called  representative consumer ). This approach leaves no role for important institutional frictions such as, e.g., financial constraints and contract-induced incentives that played a major role in the 2008 crisis. An analysis of such frictions will add vastly to our understanding of how institutions make decisions and will also allow us to explore the implications of these decisions for asset prices. I propose to depart from the representative agent paradigm and introduce explicitly institutional investors into asset-pricing models. My goal is to understand how institutions affect financial markets and the real economy and to help develop appropriate policy responses.2. International macro-financeIn the past two decades, economic globalisation has produced an unprecedented rise in cross-border equity holdings. Accounting for capital gains on these equity holdings, currently disregarded both in the official statistics and in traditional international macroeconomics, may potentially overturn implications and policy recommendations of the leading theories. In this project, I seek to enrich the field by incorporating explicitly portfolio choice and capital gains on financial assets. Such a theory marries two fields of research:  international economics (Economics) and asset pricing (Finance).3. Combining the above two areasThe 2008 crisis was sparked by banks and lead to a worldwide recession. Combining the insights from the first two projects, I intend to research how the instability spreads across countries and how i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Application of genomic inversions as diagnostic markers in precision medicine' (IN2DIAG).

assistant: **Concept**

Despite the initial high expectations of genome variation studies, only a small proportion of the genetic risk of common and complex diseases has been identified so far. Most of the work has focused on single nucleotide polymorphisms (SNPs) and copy number variants (CNVs). Inversions, on the other hand, are a type of structural variant that affects a large fraction of the human genome and is implicated in phenotypic differences in diverse organisms. However, they have been poorly studied because their specific characteristics make their detection especially challenging and how much they contribute to human diseases is not yet well known. As part of the INVFEST ERC Starting Grant, we have developed a novel high-throughput technique for genotyping multiple human inversions in hundreds of individuals, which opens new opportunities in the characterization of inversion functional effects and their association with diseases. The aim of the IN2DIAG project is to increase the value of this technology as an innovative diagnostic kit for human inversions that could be licensed to an industrial partner for its commercialization. To achieve that, the main goals are: (1) Carry out a proof of principle study of the association of inversions and 10 common diseases and other health-relevant traits to demonstrate the potential applicability of the technology; (2) Extend the current market research of inversion genotyping needs in a clinical setting and strengthen the contacts with potential licensees and end-user companies; and (3) Maintain the current IPR strategy and if necessary expand this protection with additional patents of possible new discoveries. Our project therefore involves a combined approach, strengthening both the scientific and commercial aspects of the technology, to b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Unveiling algaenan metabolism in eukaryotic microalgae' (BreakThrough).

assistant: **Concept**

Microalgae are exceptionally rich in essential nutrients such as proteins and fatty acids (e.g., omega-3 fatty acids). Their cultivation requires significantly less land and water compared to traditional crops, reducing the strain on these resources. However, accessing the nutrients of eukaryotic microalgae as a food source, particularly from the economically important genera Nannochloropsis and Chlorella, requires substantial resources. These algae are encapsulated by a resilient cell wall composed of a polymer known as algaenan. The development of algaenan-deficient strains or enzymes degrading algaenan to make nutrients accessible, has been hindered severely by the lack of knowledge about algaenan metabolism.In the BreakThrough project, I will team up with Prof. Johan Andersen-Ranberg from the Department of Plant and Environmental Sciences of the University of Copenhagen. The goal is to clarify the evolutionary conserved mechanisms underlying the algaenan metabolism throughout the cell cycle, particularly during autospore release. The proposed work involves co-expression analysis, genetic engineering, confocal microscopy and high-resolution mass spectrometry to identify and characterize the genes in algaenan metabolism in the eukaryotic microalgae Nannochloropsis oceanica. Insights obtained in this project will benefit both fundamental and applied sciences. On the fundamental side, BreakThrough will uncover the biochemical process underlying algaenan anabolism and catabolism. For the applied aspect, the project will improve the use of microalgae as a future food source and biotechnological applications by developing energy-efficient and food safe methods to bypass the recalcitrant algaenan polymer in extraction processes.


**Keywords:** Microalgae metabolism, eukary
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Drug Repurposing for Malaria Chemoprotection' to be submitted under Horizon 2020.

assistant: **Abstract**

Malaria is a serious parasitic disease afflicting 198 million people in 2013, with an estimated death toll of approximately 600 000. Approximately half the world’s population is at risk of malaria. So far there is no cure/vaccine against malaria and current chemoprotective treatments have shortcomings, such as: 1) Limited Number of Drugs effective against malaria parasites; 2) Adverse Side Effects (observed in 32% to 44% of users); 3) Parasite Resistance to most of the drugs used for prevention and treatment; and 4) Limited Use (restrictions on age, genetic traits, pregnancy, etc). Our ERC-funded research uncovered a novel mechanism of action that can be targeted for malaria chemoprotection, with fewer side effects and reduced propensity to generate parasite resistance, on which we filed for IP protection. Furthermore, we have identified a set of likely drug candidates already validated in the clinic, which are likely candidates for malaria chemoprotection. In fact, our preliminary data indicates that a known anti-diabetic drug significantly affects parasite growth. We are seeking funding to initiate pre-clinical studies for repurposing this drug for malaria chemoprotection. This PoC funding will allow us to complete the following aims: 1) in vitro profiling to define therapeutic dose for malaria chemoprotection; 2) in vivo profiling to perform efficacy and toxicity studies; 3) further define IP Strategy; 4) draft early stage Regulatory Approval Roadmap; 5) conduct Market Analysis and develop a Business Case.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'An online digital logbook to protect and prove authorship, and to share scientific results' (ResearchProof).

assistant: **Concept**

The scientific publishing sector is facing significant challenges related to authorship and dissemination of research outputs. Currently, authorship acknowledgement is provided only upon final publication of a paper, which can be a lengthy process. As a result, sharing of unpublished results is rare, leaving the potential of the early dissemination of scientific work unexploited and ultimately slowing down the pace of research worldwide.Innovaetica has developed ResearchProof, an open access (OA) online platform for depositing, pre-publishing and sharing scientific work from any discipline and at any stage of the research cycle. Its core feature is a digital logbook where researchers can store any kind of (intermediate) research artefacts, obtaining a legally valid proof of authorship thanks to timestamping technology. The innovative use of blockchain cryptography makes for a particularly safe environment that relies on a distributed, decentralized database architecture. ResearchProof overcomes the limitations of conventional publishing by offering speedy publication without editorial bias or lengthy pre-publication peer review as well as instant intellectual property protection for scientific data even for intermediate research outputs. Thanks to the pre-publication and sharing functionality, scientists can make such findings immediately available to the scientific community, receiving proper credit and boosting their chances of gaining access to new collaborations, publications and grants.The ResearchProof project contributes to enabling broader access to scientific publications and data, in line with the ideas of a global knowledge society and of the European Research Area.The phase 1 feasibility study will focus on validating the business model and commercialization
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'An innovative, fully automated, intelligent vehicle fire and smoke detection and extinguishing system for buses/coaches', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Between 1999 and 2004, there was an average of 122 bus fires reported in Sweden alone, and that this equated to buses being 5 to 10 times more likely to catch fire than trucks. In addition, estimated unreported bus fires are 2/3 of reported incidents (~ 81 incidents). In the EU27 alone, there are an estimated 700,000 buses and coaches in use and about 35,000 buses sold annually – of these only 25% have some sort of fire protection systems.The major drawback of existing systems is that they only react to a fire incident and cannot prevent its occurrence. Current vehicle fire detection and suppression systems also have following problems:-They cannot determine the extent of the problem and locate the actual position of the problem and therefore a graduated response is not possible;-They are incapable of giving early warning of potential problems such as electrical faults; and-They are stand-alone systems, and are not integrated into the vehicle (Can-Bus) control system, with the result that fuel flow cannot be stopped in the event of a fire.VULCAN will develop a fully automated, intelligent, fixed installation, vehicle fire and smoke detection and extinguishing system for buses and coaches. The system will comprise of heat and aspirating smoke detectors and a fire extinguishing system controlled by an intelligent response system embedded in the vehicle CAN-bus control system. The VULCAN project will help the European bus and coach operators to increase passenger safety and reduce bus fires by up to 25% through predictive detection.The VULCAN project will focus on developing three important subsystems and components:a) Vehicle smoke detection systemb) Optimal agent tank, nozzles and piping system design, andc) Control system integrated with vehicle Can-Bus control systemOu