RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Disrupting the economy – FinTech blockchain solution revolutionises direct payments. Secure, low-cost and simple bank-free payments for everyone' (BILLON), addressing dissemination and exploitation.

assistant: **Impact**

The number and volume of non-cash transactions has been increasing in the recent years, which makes the technological limitations of the existing IT systems more apparent than ever. The low performance of the centralised IT architecture increases the maintenance cost, that are transferred to customers. The European Commission revealed that growing bank fees are leading to financial exclusion of the poorest citizens. It is estimated that 2.5 million Europeans who applied for the bank account have been rejected for being too poor.The technological issues of centralised IT systems are too difficult to be solved without making a disruptive change in the banking industry. When the regulated services cannot be offered, there is a room for non-regulated products which compromise on financial market security, e.g. cryptocurrencies like bitcoin.Our value proposition is Billon - a distributed ledger technology for creating free current accounts enabling making ultra-low cost payments with real currencies (EUR, GBP, PLN) in a regulated manner. The disruptiveness of Billon arises from:(1) distributed architecture developed on blockchain by our specialists, (2) compliance with the EU regulations upon the agreements with banks and ongoing FCA Regulatory Sandbox in the UK.After introducing the first free current account in a smartphone and finishing pilot trials with our business partners, we apply for the SME Instrument to expand the Billon ecosystem. The proposed project is addressing market segments of mass payouts for corporate customers and social & media online payments for online users.Billon is aiming to disrupt the market of alternative payments, which will be worth $1,400 billion in 2019. Our business model is to make profit on corporate customers, willing to enhance digital
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Role of Foxp3 in immune tolerance in EAE the murine model for multiple sclerosis'.

assistant: **Concept**

Multiple Sclerosis is the chronic neurological disease the most frequent in the young adult. This disease is characterized by an inflammatory attack of the central nervous system, which leads to the destruction of the myelin gain of the axon. The animal model of this disease, the EAE (experimental autoimmune encephalomyelitis) permitted to better characterize this auto-immune disease.More recently, the role of a specific population of lymphocytes the CD4+CD25+ regulatory T cells (Tregs) in the regulation of autoimmunity was brought to light. These cells were generated in the thymus and there is a decrease in the number and function of this class of regulatory T cells in Multiple Slerosis patients, suggesting that the loss of these cells promotes the induction and the persistence of the disease.In EAE, there is now considerable evidence that Tregs are involved in genetic resistance and in mediating remission of the disease. Thus understanding the molecular and cellular mechanisms by which CD4+CD25+ T cells a re induced and the mechanism by which they inhibit induction of autoimmunity is crucial and has not yet been elucidated.Recently, the expression of the transcription Foxp3 factor was shown to be enriched in CD4+CD25+ Treg cells and forced expression of Foxp3 was shown to convert murine naïve T cells into regulatory T cells. Foxp3 may initiate a genetic program that converts naïve T cells into anergic cells, which then function as Tregs.In this work, we propose to study the central role of Foxp3 in inhibiting effector functions, inducing anergy, and generating regulatory T cells in vivo. This work will permit me to study the molecular mechanisms of tolerance.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Structure-function relationship of chimeric KdpFABC complex' in the context of a Horizon 2020 call.

assistant: **Objectives**

The structure-function relationships that explain the transport mechanism of membrane proteins on a molecular level are poorly understood and define one of the most complex and interdisciplinary research fields at the interface of Biology, Chemistry and Physics. Here I propose the investigation of the KdpFABC complex for the potassium uptake into the cell. It combines features of three membrane transport systems (P-type ATPases, channels and ABC transporters), which traditionally are considered to be mechanistically and structurally distinct. I propose to decipher the mechanism of action of the KdpFABC system, which is likely to overthrow the conceptual boundaries conventionally used to describe membrane transport mechanisms. The work might lead to the design of novel antibiotics, as these systems are exclusively found in prokaryotes. The structural studies will be conducted exploiting the recent breakthroughs in high-resolution single particle cryo electron microscopy (cryo-EM) that will be established by me as experienced researcher and thereby contribute to the cutting-edge research at UG. The complementary expertise of myself in structural biology and of Prof. Slotboom, as a world-leading scientist in the functional characterization of membrane proteins, are ideally suitable for the successful completion of the research objectives. Ultimately, this project will provide me a unique opportunity to establish myself as an independent researcher and use the knowledge and skills acquired to obtain an academic position within the EU.


**Keywords:** "high-resolution single particle cryo-EM""""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'School Opportunity Structure and Student Achievement in Comparative Perspective' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Most of the low achieving students are of low socioeconomic background. Low educational profile of their parents leaves these students in the educational system without any proper guidance. Scholars have emphasized the role of relations with peers and teachers in compensating for this negative background characteristic. Indeed, supportive and trusting relationships with peers, teachers and adults in school settings are essential to academic learning. However, little is known about the ways in which school opportunity structure shape these relationships. This project focuses primarily on two school types generating differing student achievements; Vocational High School (low student achievement) and General High School (relatively high school achievement) in Turkish educational system. In doing so, the proposed project aims at exploring in depth in what ways school opportunity structures in these two school types effect students’ school-based networks and their achievement.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Enacting heritage: The aesthetic dynamics of cultural transmission'.

assistant: **Concept**

Aesthetic behaviours and expressive activities carry out a crucial role in human cultural evolution. Aesthetic cognition is important for intersubjective attunement already in early childhood, and attends to cultural emergence and transmission of ideas, practices and norms. However, anthropological scholars haven't ever investigated the cognitive dynamics whereby aesthetic behaviours shape the symbolic processes of constitution and re-enactment of cultural heritage. The proposed research project seeks to address this lacuna by dealing with key issues relating to the role of aesthetic behaviours in cultural transmission. The study focuses on how aesthetic and expressive elements are mobilized in the course of social interaction creatively transforming and communicating knowledge.The originality of the proposed approach lies in the interdisciplinary methodology that has not been used in previous studies of the subject matter. For the first time, a naturalistic and cross-cultural model of aesthetic behaviour will be applied to the context of cultural evolution. Existing naturalistic studies of aesthetics are characterized by a reductionist approach, whereas research on cultural transmission suffers due to the divide between cultural and evolutionary perspectives. This project aims to overcome the traditional opposition of “evolutionary psychology versus ethnography” through an interdisciplinary study of the multimodal, expressive, symbolic, and non-verbal practices whereby human beings collectively perform and share knowledge.The principal result of the project will be the first systematic and comparative analysis of aesthetic behaviours as operative components of cultural transmission. This result will be of interest to a broad scientific audience and will enhance several
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Computer simulations of electrically charged polymers' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

The proposal is directly related to the applicant's work at the Max-Planck Institute for Polymer Research in Mainz, Germany, conducted within the 5th Framework Program Research Training Network - HUSC - From Hard to Ultrasoft Colloids. All the experience as well as knowledge of the soft matter physics gained there will be transferred to his country of origin within the reintegration grant. The main objectives of the project are Monte Carlo computer simulation studies of the complex phenomena occurring i n systems of electrically charged polymers, counterions and salt ions. The calculations will be performed with respect to various conditions set by the actual values of free, variable simulation parameters. Furthermore, by changing the temperature, the effect of variation of the so-called interaction strength on the polyions conformational properties will be examined. Within the studies, both static and dynamic quantities characterizing polymer behaviour in thermodynamic equilibrium will be inspected including the mean radius of gyration, internal energy, correlation functions, diffusion coefficients and the like. Whenever possible, the obtained computational data will be compared to the existing theoretical predictions. In order to observe possible multi-molecular effects, systems consisting of single macromolecules and several ones will be dealt with. Since the simulations will be computationally demanding, the use of a cluster of two-processor computers running under the operating system of Linux is planned. The proposed project in a natural way follows the world's trends in soft matter physics and, as such, is going to improve EU scientific excellence as well as the attractiveness and competitiveness of the European Research Area. It will provide further insight into
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Reconstructing human oral microbiome composition changes over the last 8000 years with proteomics and metagenomics approaches' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

This project aims at reconstructing the evolution of human oral health in Northern Europeans, from the late Mesolithic to modern days, by genomics and proteomics investigation of: human ancient microbiota, human immune response proteins, and food remains preserved in mineralised dental plaque (archaeological dental calculus).The human microbiota is essential to maintain health, but capable of eliciting disease. Ecological shifts and imbalances (dysbiosis) of the oral microbiota can significantly impact health and cause severe forms of oral pathologies resulting in systemic disease at different body sites. Taxonomic reconstruction of ancient microbiomes and identification of which genes have been gained or lost in their genomes in connection with major lifestyle changes in human history will contribute to the development of more effective preventive and therapeutic approaches for this disease.The two main research objectives are:• Reconstruction of the evolution of the oral microbiome composition over the last 8000 years, and• Characterisation of the associated human immune responses.Genomic and proteomics biomolecular evidence will be retrieved from archaeological human dental calculus: a rich, but so far mostly neglected, source of ancient oral biomolecules. Ancient DNA and proteins extracted from archaeological dental calculus will be analysed using state-of-the-art proteomics and metagenomics approaches at the Centre for GeoGenetics, by high-resolution mass spectrometry and high-throughput DNA sequencing-by-synthesis methods. CGG recently led a high-profile study demonstrating the potential of this approach and will further develop this concept using approximately 80 Northern European samples from a wide chronological range. The Researcher’s skills in computational p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'What makes us curious? The role of metacognition.' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Curiosity is a basic biological drive that has a profound influence on our behaviour, choices and learning. Despite the vital role it plays in our daily lives, its functions, mechanisms and neural basis remain poorly understood. It has been proposed that the intensity of curiosity for certain information is tightly linked to the ability of that information to reduce uncertainty, thereby closing the gap between what is currently known and what is yet to be discovered. This project proposes that the ability to monitor one’s levels of knowledge and uncertainty (metacognition), is critical to the effective deployment of curiosity. The goal of this project is to unravel how metacognitive processing modulates curiosity. The relationship between metacognition and curiosity will first be systematically probed in a behavioural experiment that will investigate this relationship in both a learning and decision-making context. Computational modelling will further elucidate these relationships, and help to inform a theoretical model of curiosity as a metacognitive process. The cutting-edge decoded neurofeedback approach will then be used to selectively disrupt metacognition and curiosity in order to establish a causal relationship and determine the directionality of the effects. This project will be the first to combine experimental, neural and computational approaches to unravel the dynamics of the relationship between metacognition and curiosity. This integrative approach will result in a unified theoretical and mechanistic account of curiosity, which will provide a strong foundation for future research in this field. The findings will have far-reaching implications for diverse fields such as learning, decision-making, and robotics. A better understanding of curiosity and metacogn
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Linking singularity theory and representation theory with homological methods'.

assistant: **Objectives**

In algebraic geometry one tries to understand and explain geometric phenomena of zerosets of polynomial equations (algebraic varieties) with algebraic techniques. Singularities of algebraic varieties are, roughly speaking, points of indeterminacy, where most analytical methods collapse. Geometrically, this corresponds e.g. to cusps or crossing points. In a practical example, the arm of a robot can break if it passes through a singular point, which could result in a complete breakdown of the system. Such a situation should be avoided by theoretical considerations.This project lies at the intersection of singularity theory, (non-commutative) algebraic geometry, commutative algebra, and representation theory. The main goal is to develop homological methods to understand geometric phenomena of algebraic varieties in the presence of singularities and use them to study representation theoretic concepts such as cluster categories and friezes. The project will provide a bridge between these seemingly distant areas that can be exploited in both directions.The specific research objectives: (1) Construction of noncommutative (crepant) resolutions of singularities (NC(C)Rs), in particular for not necessarily normal varieties/rings: computation of global dimension, application to positive characteristic (global dimension of ring of differential operators)(2) McKay correspondence for reflection groups: study of the geometry of discriminants of pseudo-reflection groups and their  relation to the representation theory of the groups, characterization of McKay quivers(3) Friezes and singularities: show how (higher) integral friezes can be constructed from cluster categories and categories of maximal Cohen-Macaulay modulesThe project will be carried out by Eleonore Faber, supervised by Ro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Science for Life' (SciFe).

assistant: **Concept**

Main objectives of the SciFe proposal is to bring researchers to the general public, to inspire youngster to embark on scientific careers, to increase awareness of importance of research and innovation activities, with a view to supporting the public recognition of researchers creating an understanding of the impact of researchers' work on citizen's daily life. For that purpose the awareness campaign (AC) to convey messages under the slogan “Science for Life” will be used in 2016 and 2017. On Fridays 30.9.’16 and 29.9.’17 SciFe events will be organized with renewed programs in festive and fun atmosphere in Ljutomer, Maribor, Brežice, Ljubljana, Koper, Izola and Nova Gorica. All SciFe events’ activities aim at offering the public at large an opportunity to cooperate in fascinating experiments, demonstrations, observations etc., to socialize and have fun with researchers in a relaxed atmosphere. The program is appropriate for public in general, regardless their scientific program and especially designed for youngest. SciFe programs’ red line is contribution of science to life in various aspects. The »European corner« will be prepared in the heart of every RN location: the visitors will be offered information on EC’s various actions and programs, EU material, “the Charter and the Code”, information how young people can become researchers and Framework Program witness’s experiences. Intensive awareness campaign is designed according to its main target. The rich communication mix includes active engagement of the young people through the public call targeting primary and secondary schools. Last but not least, the impact assessment will focus to measure the success and the impact of SciFe activities. All that will be achieved through consortium management of all WPs and harmo