RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Polyesters Catalytic Chemical Recycling in Continuous Flow Reactors' (REFLOWER), addressing dissemination and exploitation.

assistant: **Impact**

Establishing a circular economy requires the development of plastic chemical catalytic recycling (CCR) processes, where catalysts are employed to produce high-value compounds from waste plastic streams. Polyesters such as polyethylene terephthalate (PET), polylactic acid (PLA), and polyhydroxybutyrate (PHB) are among the most abundant plastic wastes, primarily from packaging. However, current CCR methodologies are either poorly selective, resulting in low-value mixtures used as fuel, or are conducted in discontinuous operations that are difficult to scale. To address this, conducting CCR in continuous flow systems with selective and active heterogeneous catalysts has the potential to unlock new valorisation pathways. Here I will propose the first proof-of-concept for a liquid-phase, heterogeneously catalysed continuous flow CCR process for three polyesters (PET, PLA, PHB). The aim is the selective and sustainable depolymerization of common polyesters into reusable chemicals using unconventional, innovative bifunctional monolithic catalyst. This will be pursued through two complementary objectives: the synthesis of interconnected, hierarchically porous 3D-shaped solid bifunctional catalysts composed of metal nanoparticles supported on acidic mixed oxides, and the demonstration of the hydrogenative depolymerization of these three polyesters (PET, PLA, PHB) in a continuous flow system using the catalyst. Ultimately, this CCR methodology will provide an innovative technology that advances existing processes and contributes to establishing new recycling pathways for waste plastics. Eventually, it will support the development of a circular economy for plastics and help reducing the societal environmental impact.


**Keywords:** Plastic Chemical Recycling, Depolymerization, PE
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Prefrontal and cingulate interactions in cognitive control: reversible inactivation and electrocorticograms'.

assistant: **Objectives**

An important feature of human cognition is its remarkable flexibility. Cognitive control refers to processes that allow behaviour to vary adaptively depending on current goals. Understanding it is therefore fundamental to knowing how our behaviour can be adapted and flexible. Deficits in cognitive control, and imbalances in related neurotransmitters such as dopamine, are associated with a number of psychological and neurological conditions, including schizophrenia and the cognitive symptoms of Parkinson’s disease. Both prefrontal cortex (PFC) and anterior cingulate cortex (ACC) are known to have important roles in cognitive control, but the details of how they achieve this, how they interact, and the roles of those neurotransmitters are unclear. An important way to discover this is to record the effects of inactivating those regions and neurotransmitter systems, as this reveals how these systems are critical to cognition.This project will reveal the nature of the frontal lobe interactions that subserve cognitive control, and their neurochemical basis, by combining inactivation and neurophysiological techniques.In macaque monkeys performing a well-established test of multiple elements of cognitive control, we will reversibly inactivate targeted regions of ACC and PFC whilst simultaneously recording continuous neurophysiological data using chronically implanted electroencephalography. We will go on to record the same data during reversible localized blockade of targeted neurotransmitter systems, beginning with dopamine, and then to functionally disconnect ACC and PFC.The project will have significant benefits for both fundamental and clinical research, and represents a rare combination of techniques made possible by mobility between laboratories. It will substantially enh
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Support of the 5th european conference on turbomachinery - fluid dynamics and thermodynamics, praha, march 18-21, 2003'.

assistant: **Innovation**

Objective of the proposal is the support of the 5th European Conference on Turbo machinery Fluid Dynamics and Thermodynamics. The Conference endorsed by 10 European Eng. Associations, replaces similar previous national conferences. The Conference covers all aspects of Turbo machinery design and operation in order to improve the technological level of Turbo machinery design products and their operation as part of propulsion and energy conversion systems. The Conference wants through a rigorous review process, obtain a high level of scientific quality in order to offer and stimulate the best European intellectual capability in the field of the crucial equipment involved in the Energy Conversion and propulsion. It is intended to be a primary event for technology transfer across Europe through the presentation of latest developments and best practice. The Conference will offer reduced fee for students and people from East European Countries.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Exploring Chemistry under Vibrational Strong Coupling'.

assistant: **Objectives**

Exploring Chemistry under Vibration Strong Coupling:  In the past several years, it has been shown experimentally that a cavity quantum electrodynamics phenomenon called vibrational strong coupling (VSC) can change chemical reactivity. This includes modification of reaction kinetics, product distributions and binding thermodynamics. VSC relies on the formation of hybrid light-matter states created by coupling molecular vibrations to photonic cavities. VSC utilizes light-matter interactions, without the need for any light as such, to modify the molecular wavefunction. The possibility of modifying chemical reactivity with VSC has generated considerable excitement in both academia and industry around the world. However, nobody is yet able to predict the outcome of chemical reactions under VSC. We lack an established theoretical framework and have only a limited number of experimental studies to rely on. This poses both a fundamental question and an impediment towards any future application. There is now a clear need for a systematic approach to reach a new level of insight and understanding of the underlying mechanisms at play in this phenomenon.  This project proposes a systematic approach to study chemical reactivity under VSC in order to establish when and how VSC affects reactions and their mechanism. A single reaction, acyl substitution, which occurs on many structurally different substates will be examined in depth using tools like Hammett mapping and Eyring analysis. Subsequently, different reactions of a single functional group, being the carbonyl group, will be screened for VSC effects. All of this serves to uncover any pattern of effects experimentally and will generate a rich data set which can be used by theory groups construct new models and verify existing on
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Photonics on Germanium - New Industrial Consortium' (PhotoGeNIC).

assistant: **Innovation**

The project scope is to develop an innovative technology of germanium (Ge)-based VCSEL. The main objective is to develop a Ge-VCSEL epi-growth by MOCVD and MBE techniques and processing of high performance and reliable lasers to be integrated in 3D camera and LiDAR demonstrators. The key challenge is to achieve high crystal quality of grown layers while taking the advantage of a better crystallographic lattice sameness between Ge and Al gallium arsenide (GaAs),  which enables to decrease misfit defects density and in consequence to increase the quantum efficiency of the device. Several characterisation methods will be used as X-ray diffraction and topography, depth high resolution SIMS, electron microscopy (SEM/TEM), atomic force microscopy, reflectance, PL mapping, and others.  Each growing campaign will be concluded by processing of conventional VCSELs (GaAs-based) and VCSELs on Ge which will allow the verification of VCSELs parameters and comparison of both type devices. The VCSEL technology drives a dynamic market with constant need for innovative solutions. Demonstration of high performing devices of Ge-on-Si can unlock potentially large markets from optical data communications to imaging, lighting and displays, to the manufacturing sector, to life sciences, health care, security and safety. In commercial applications, the performance, costs and the strong reduction of toxic elements will be very important factors to drive a replacement of the current technology.  The Ge, offering a higher yield and less production losses due to higher uniformity at larger size wafer, is promised to lower the environmental burden compared to expensive GaAs substrate. As the VCSEL sector is developing dynamically with laser production expected to triple in the next five years, the p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Biomimetic Organocatalysis – Development of Novel Synthetic Catalytic Methodology and Technology' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Biomimetic Organocatalysis – Development of Novel Synthetic Catalytic Methodology and Technology The objective of the proposed research is the design and development of unprecedented preassembled, modular, molecular factories. Inspiration comes from nature’s non-ribosomal peptide synthetases (NRPSs) and polyketide synthetases (PKSs). These large multifunctional enzymes possess catalytic modules with the capacity for recognition, activation and modification required for sequential biosynthesis of complex peptides and polyketides. Using nature as a role model we intend to design and prepare such catalyst “factories” synthetically and apply them in novel cascade reaction sequences. The single catalytic modules employed will be based on organocatalytic procedures, including enamine-, iminium-, as well as hydrogen bonding activation processes, but the potential scope is limitless. Organocatalysts have so far never been applied in a combined fashion utilizing their different activation mechanisms in multiple reaction cascades. Therefore, it is our intention to firstly demonstrate that such a production line approach is feasible and that these new catalyst systems can be applied in the synthesis of valuable enantiopure, biologically active, building blocks and natural products. Additionally, the extensive possibilities to vary organocatalyst modules in sequence will lead to science mimicking nature in its diversity.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'The Combination of Electrochemistry and Nickel Catalysis: New Bond-Forming Reactions on a Sustainable Platform'.

assistant: **Objectives**

Sustainable routes towards the formation of key synthetic carbon–carbon bonds by cross-coupling remains a challenge in organic chemistry. Realization of this goal will enable the combination of simple building blocks to rapidly assimilate synthetic complexity with only a minimum level of stoichiometric waste. Electrochemistry provides a new platform to conduct reactions through in situ generation of reactive intermediates under mild conditions, with broad applications to industrial synthesis. Herein, we seek to combine the fields of electrochemistry and cross-coupling reactions, using an electric current to catalytically generate alkylzinc reagents and reactive alkyl radicals. These intermediates will then undergo coupling, facilitated by nickel catalysis, to generate key carbon–carbon bonds, including challenging C(sp3)–C(sp3) bonds. Furthermore, the powerful combination of electrochemistry and nickel catalysis will enable the simplest feedstock chemicals – alkanes – to be utilized for the first time in cross-coupling through a nickel chain-walking process, providing facile access to fatty acids and alternative coupled products. These projects will enable the emergence of new reaction strategies for exploitation in a sustainable manner. Additionally, this ambitious and innovative proposal will succeed through considerable two-way transfer of knowledge between the participating organizations and the ER, developing the fellow into a leading international researcher.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Artificial Intelligence for Traffic Safety between Vehicles and Vulnerable Road Users'.

assistant: **Concept**

Traffic safety is the fundamental criterion for vehicular environments and many artificial intelligence-based systems like self-driving cars. There are places, e.g., intersections and shared spaces, in the urban environment with high risks where vehicles and vulnerable road users (VRUs) such as pedestrians and cyclists directly interact with each other. By advancing starte-of-the-art artificial intelligence methodologies, this project VeVuSafety aims to build a privacy-aware deep learning framework to learn road users’ behaviour in various mixed traffic situations for the safety between vehicles and VRUs. VeVuSafety proposes a 3D environment model based on 3D point cloud for privacy protection — private information like license plates and face is anonymized. Then, within this environment model, an end-to-end deep learning framework using camera data will be built for multimodal trajectory prediction, anomaly detection, and potential risk classification based on deep generative models such as Variational Auto-Encoder. Additionally, an active privacy mechanism will also be adopted by application of the differential privacy mechanism to help the deep learning models prevent model-inversion attack. Moreover, the framework’s generalizability will be investigated by exploring the Normalizing Flows approach for domain adaption. The framework’s performance will be validated at different intersections and shared spaces using real-world traffic data. Besides road user safety and privacy, VeVuSafety can help traffic engineers and city planners to better estimate the design of traffic facilities in order to achieve a road-user-friendly urban traffic environment. Furthermore, the success of VeVuSafety will enhance the fellow’s scientific knowledge and project management skills to be
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Molecularly targeted therapy for T cell acute lymphoblastic leukemia'.

assistant: **Concept**

T cell acute lymphoblastic leukemia (T-ALL) is an aggressive T cell malignancy that is most common in children and adolescents. Our current understanding of the molecular genetics of T-ALL indicates that leukemic transformation of thymocytes is caused by the cooperation of mutations that affect proliferation, survival, cell cycle, differentiation and self renewal. Molecular analysis has identified a large number of T-ALL specific oncogenes, but the genetic defects that are implicated in the aberrant proliferation and survival of the leukemic cells remain largely unknown. It is the aim of this project to continue the molecular characterization of T-ALL using genome wide analyses, focused RNAi screens, and drug library screens to identify oncogenes that specifically provide proliferation and survival advantages, as well as other targets for therapy in T-ALL. In addition, we will study the cooperation of these oncogenes with other oncogenic events using in vitro and in vivo mouse models, and use those models for the development and characterization of novel therapeutics. This project will generate novel insights in the molecular pathogenesis of T-ALL and aims at translating this information towards novel targeted therapies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Establishment of the Bioinformatics ERA Chair at the Cyprus Institute of Neurology and Genetics' under Horizon 2020.

assistant: **Concept**

The BIORISE project proposal aims at the establishment of a Bioinformatics ERA Chair at the Cyprus Institute of Neurology and Genetics (CING). CING is currently the most advanced organisation of Cyprus in the fields of Neurology, Genetics and Biomedical Sciences and its research infrastructure is strongly supported by European Structural and Investment Funds (ESIF) through the Cyprus Directorate General for European Programmes, Coordination and Development. Through BIORISE the CING will attract talented Bioinformaticians who will be integrated within its current organisational structure to satisfy urgent needs for Bioinformatics analyses. The CING has recently established a Translational Facility infrastructure, through the ESIF and Norway grants, that will be producing a substantial amount of genomics and proteomics data. Due to budget limitations and the current economic constraints of the country, recruitment of expert Bioinformaticians has not been possible. Therefore, establishment of the Bioinformatics ERA Chair through this funding opportunity will complement and upgrade the above investments, since it will enhance the timely analysis of data and contribute towards excellence in extraction of reliable and meaningful results from large biological datasets. Furthermore, the more effective analysis of genomic and proteomic data will increase the capacity and level of excellence of CING thus promoting participation in competitive research proposals at national and international levels. In addition, BIORISE will facilitate the introduction of a Bioinformatics course within the postgraduate programmes of the Cyprus School of Molecular Medicine thus promoting the education and training of young scientists in the cutting edge field of Bioinformatics. BIORISE will have an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Sustainable liquid fuels from CO2 electroreduction' (CO2RR) under Horizon 2020.

assistant: **Objectives**

Fossil fuels have been crucial for the prosperity of human society since the industrial revolution, but have also brought about many critical issues, such as global warming. To meet the ambitious goals set out in the Paris Agreement, it is imperative to explore sustainable fuel sources. Liquid fuels produced from renewable-electricity-driven CO2 reduction reaction (CO2RR) are promising candidates because they simultaneously allow for a carbon-neutral energy cycle and the storage of renewable yet intermittent energy. Due to its high energy density and suitable octane number, propanol is one of the most desired products from CO2RR as direct fuels and fuel additives. However, current state-of-the-art catalysts do not exhibit more than 15% selectivity for propanol, which is a huge impediment towards the practical adoption of CO2-to-propanol electrolysis. Raising the selectivity requires intricate knowledge of what catalyst descriptors drive propanol formation, in order to predict and discover ideal catalyst/system combinations, which are the objectives of this proposal. To achieve these goals, the optimum electrode-electrolyte interface will be identified based on well-defined single-crystal-electrode experiments; reaction intermediates and pathways will be identified and studied by in situ spectroscopy methods and DFT calculations; theory-guided-designed nanocatalysts will be synthesized and subsequently integrated into an optimized CO2RR electrolyser to produce propanol at industrially relevant current densities. Through successful completion of the proposed research, an efficient CO2-to-propanol electrolysis system will be developed together with an in-depth understanding of CO2RR mechanism.