RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Environmental chemicals as obesogens' under Horizon 2020.

assistant: **Concept**

Obesity is a serious health risk that has reached epidemic proportions worldwide. Obesity is traditionally considered a as disorder of energy imbalance imposed on a background of genetic disposition. In addition to risk factors such as diet and genetics, chemicals in our environment have emerged as contributing factors associated with an increased risk for obesity (i.e. obesogens). Phthalate esters, a ubiquitous class of chemicals used as plasticizers in products such as toys and hospital supplies, are suspected of being obesogens. Despite studies demonstrating that phthalate urine levels are associated with increased risk to obesity in children, meta-analyses report that current data are insufficient for determining whether phthalates do in fact increase the prevalence of obesity. Moreover, data are sparse on how obesogens affect metabolism and the feeding axis and there are fundamental gaps in our understanding of the precise mechanisms by which environmental chemicals exacerbate this human disease. The central hypothesis of this proposal is that exposures to phthalates will exacerbate molecular responses in the hypothalamus and gut that are observed during a regime of over-feeding. Further, the modification of the gut microbiota may be a relevant consequence of obesogens. The zebrafish (ZF) is one of the most important models in environmental toxicology and developmental biology, and is rapidly becoming a major model for studies in human health and metabolic diseases. ZF will be used to determine mechanisms that are associated to diet and chemical induced obesity, novel regulatory pathways in the hypothalamus and gut will be identified; this is important as these two tissues communicate via the endocrine system and there is direct innervation of the gut by the centra
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Training Network on Zebrafish Infection Models for Pharmaceutical Screens' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Infectious diseases caused by pathogenic micro-organisms are major causes of death, disability, and social and economic disruption for millions of people. During evolution these pathogens have developed intricate strategies to manipulate host defence mechanisms and outwit the immune system. To reduce the burden of infectious diseases it is important to increase understanding of these host-pathogen interaction mechanisms and to develop more effective strategies for drug discovery. The zebrafish holds much promise as a high-throughput drug screening model. In the last few years, zebrafish models for studying human pathogens or closely related animal pathogens have emerged at a rapid pace. The fact that zebrafish produce large amounts of embryos, which develop externally and are optically transparent, gives unprecedented possibilities for live imaging of disease processes and is the basis of novel high-thoughput drug screening approaches. In recent years good models have been developed for toxicity, safety and efficacy of drug screening in zebrafish embryos. However, the major bottleneck for development of high-throughput antimicrobial drug screens has been that infection models rely on manual injection and handling of zebrafish embryos. This limiting factor has been overcome by a unique automated injection system that will be applied in this project. The FishForPharma training network brings together leading European research groups that have pioneered the use of zebrafish infection models and partners from the Biotech and Pharma sectors that aim to commercialise zebrafish tools for biomedical applications. FishForPharma aims to deliver the proof-of-principle for drug discovery using zebrafish infectious disease models and to increase understanding of host-pathogen intera
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Nonverbal Multimodal Social Intention Modelling' (NEON), addressing dissemination and exploitation.

assistant: **Impact**

An under-explored problem in Social Signal Processing (SSP) is human social intent detection. SSP develops automated systems to interpret human social behaviour from sensors such as cameras, microphones, and wearables. Prior work estimating intent uses scenarios that are constrained enough so that the intent is determined by a congruent outcome. In reality, this is not true, otherwise emergent leaders are never female because they do not speak up and black minorities are criminals because they are often seen interacting with police. NEON addresses intention detection in more open-ended contexts involving large unstructured social gatherings such as networking or mingling events. During these events, there are no prearranged conversations, multiple conversations can occur at the same time, and all conversation come about via coordination with multiple independent actors with their own possibly conflicting goals. How do we train machines to perceive plausible intentions? Asking the individual to continuously report on their immediate intentions would contaminate their spontaneous social behaviour. NEON hypothesises that plausible social intentions are perceivable by external observers though the explanations of why (based on the behaviours of the individual and the surround social context) may vary depending on the perceivers own life experiences. To this end, NEON will develop a novel framework to harvest and learn from social intentions and their relation to future outcomes using a novel multi-task learning set up that clusters both on the traits of the perceivers as well as the observed individuals, a unified theory that situates conversations in free standing groups in both space and time and a novel Graphical Neural Network architecture to model it through multi-sens
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Knowledge to Enhance the Endurance of PEM fuel cells by Accelerated LIfetime Verification Experiments'.

assistant: **Concept**

Small scale stationary Combined Heat and Power (µ-CHP) generation is foreseen as a significant future market for fuel cells. Among the fuel cell types, the Proton Exchange Membrane Fuel Cell (PEMFC) technology is by far dominating the small scale stationary demonstration and field trials (~90%). The PEMFC has advantages related to high electric efficiency and excellent load following properties. A major hurdle to commercialisation, however, is their insufficient lifetime under realistic operation conditions. KEEPEMALIVE aims to establish improved understanding of degradation and failure mechanisms, accelerated stress test protocols, sensitivity matrix and lifetime prediction models for Low Temperature PEMFC to enable a lifetime of 40 000h at realistic operation conditions for stationary systems, in compliance with performance and costs targets. Main KEEPEMALIVE targets are to establish a robust and efficient methodology to identify & quantify main factors (and interactions) causing degradation/failure when imposed to stressing conditions and to characterise changes in PEMFC materials’ properties and corresponding performance losses using statistical designed experiments KEEPEMALIVE uses an integrated, iterative approach, using advanced statistical experiment design and result evaluation. Quantitative data obtained in situ from cell &stack tests under stressing conditions, are complemented by ex situ testing of materials, revealing corresponding changes in properties. Joint efforts of SMEs, energy companies and research community, including links to other related European activities, will contribute to strengthening Europe’s competitiveness in this area.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Neutrinos at High Energies: Disentangling Galactic and Extra-galactic components', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

In 2013 the IceCube South Pole Neutrino Observatory has received the Physics World award for the Breakthrough of theYear for the first observations of high-energy cosmic neutrinos. The discovery, indeed, represents the birth of a newresearch field, the neutrino astronomy, that can definitively shed light on the sources of high-energy cosmic-rays and on themechanisms through which they are produced. The origin of all of the detected neutrinos is still to be correctly identified. Just recently evidence for emission from the direction of the blazar TXS 0506+056 has been reported. The mostimportant point to understand is if the neutrino events are all of extra-galactic origin or a galactic component is present, andwhich are the specific characteristics, like size of the acceleration region and magnetic field, of the possible sources. Toachieve this goal a multi-messenger approach is necessary. In particular, it is important to compare the single point sourcesavailable in the current gamma-ray catalogues with the IceCube data, considering their spatial, timing and energydistribution. After identifying specific plausible candidates for the IceCube events, it is possible to consider the sensitivity ofgamma-ray experiments, like the High-Altitude Water Cherenkov Observatory and the planned Cherenkov Telescope ArrayProject, to verify the origin of the IceCube events. For the final correct identification of the IceCube neutrinos, the detection ofthe events from different experiments will be fundamental. In this regard, the estimation of the prospects for ANTARES, forthe possible extension of IceCube and for the planned cubic kilometre neutrino telescope in the Northern Hemisphere,KM3NeT, is mandatory.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Development and testing of a new coloring process for aluminium oxide layers' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

In order to increase the corrosion resistance and to obtain a decorative effect, the oxide layer of aluminium and its alloys can be intensified by chemical and electrochemical processes. This oxide layer is colored, using different procedures, in order to obtain a decorative effect. The demand on colored oxide layers in the architecture and the automobile industry is that they be light fastness and resistant to weathering and provide a sufficient corrosion protection of the layers. If aluminium oxide layers can fulfil these requirements, this would contribute to making colored oxide layers attractive again for the market. Above all, by an attractive coloring, the acceptance and the sales of aluminium products would increase. By this means, the business results of the branch can be favorably influenced, especially the competitivity with regard to countries having low wages. The testing of the procedures ensues in laboratory and field experiments. A coloring procedure which meets the demands of the market would mean a considerable advantage in competition for the small and medium-sized enterprises within Europe. The results will be carried over into the elaboration of new regulations and into the revisions of national and international norms.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'The gut microbiome as a mechanism underlying predator foraging behaviour and predator-prey interactions', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Aposematism is a widespread antipredator defence where prey advertise their chemical defence with warning signals. Previous work has demonstrated high within-species variation in how quickly predators learn to avoid aposematic prey, and this heterogeneity among predators is suggested to play an important role in the evolution of prey defences. This project aims to investigate what maintains the observed variation in predator behaviour by focusing on an unexplored mechanism: a predator’s gut microbiome. Evidence from humans and laboratory animals shows that gut microbiome can influence learning, memory and foraging choices (the microbiome-gut-brain axis), and theoretical models predict feedback loops between gut microbiome, diet and host behaviour. Here, I will translate this to the ecologically relevant context by 1) quantifying how the consumption of prey toxins alters the predator gut microbiome, physiology and foraging behaviour, 2) testing the effect of the early-life gut microbiome on foraging behaviour, and 3) determining the causal effect of the gut microbiome on foraging behaviour. I will use wild great tits (Parus major) as predators and combine several methods that include manipulating birds’ gut microbiome with prey toxins and faecal microbiota transplantation, quantifying gut microbial compositions from faecal samples using 16s rRNA sequencing, and conducting behavioural experiments to test avoidance learning, memory and dietary wariness. The results will address the current knowledge gaps in the predator-prey field by providing insights into the mechanisms that underly variation in predator behaviour. Furthermore, the project will advance our understanding of the ecological and evolutionary consequences of microbiomes for species dynamics. This will complem
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'A Collaborative Paradigm for Human Workers and Multi-Robot Teams in Precision Agriculture Systems' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

In CANOPIES, our goal is to develop a novel collaborative human-robot paradigm addressing the challenges of Human Robot Interaction and Human-Robot Collaboration in the unstructured highly dynamic outdoor environment of permanent crop farming (Agri-Food Area). Our approach will be demonstrated through an integrated system composed by farming robots and  logistics robots with a real-world validation of two economically relevant agronomic operations within a table-grape vineyard: harvesting and pruning.  CANOPIES represents the first attempt to introduce a collaborative paradigm in the field of precision agriculture for permanent crops where farmworkers can efficiently work together with teams of robots to perform agronomic interventions, like harvesting or pruning in table-grape vineyards. Both operations require complex processes of perception, communication, shared planning in agreement, prediction of human intentions, interaction and action. But also, both agronomic operations should be done in real life conditions, that is, in changing illumination and cast shadows, changing agronomic situations, where the vine branches or grapes can make it difficult to harvest or prune in a safe manner, due to the robot physical proximity to the human, while operating in real time.  CANOPIES ambition will be achieved by introducing: i) novel human-robot interaction methodologies for enhanced safety and coexistence, ii) novel human-robot collaboration methodologies for increased system adaptability and intuitive usability; iii) novel multi-robot coordination methodologies for improved scalability.  CANOPIES impact will contribute to filling the current gap in the development of fully autonomous robotic solutions for permanent crops by introducing a novel concept of farming robots, w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Development of an autonomous solar thermally driven distillation system' to be submitted under Fourth Framework.

assistant: **Abstract**

This proposal regards the design, installation and testing of an efficient solar-thermal distillation completely autonomous system for sea water desalination, for remote areas such as small island communities and coastal areas. The system utilises solar energy to produce the heat required for water distillation and photovoltaics to supply the energy required by auxiliary system components. The RTD goals which need to be achieved are: - The efficient use of solar collectors (type of collectors, heating fluid etc.) for producing the heat for heating and evaporating the sea or brackish water. - Design and manufacturing of the water vapour condensation surface. - Design and manufacturing of the heat exchanger for heating the sea or brackish water. - Determine the right size of photovoltaics to power all auxiliary equipment, (water pumps. control system etc.). - Optimisation of the whole system performance through computer simulation. The overall objective of the proposed system is to reduce the cost of produced fresh water by afactor of two in relation to other desalination technologies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Exploring the Potential of Microfluidics and Compartmentalisation for Selections in Directed Evolution'.

assistant: **Objectives**

Miniaturisation has become a driver of technological and scientific advance for problems that can only be solved by combinatorial approaches, requiring comprehensive testing of each member of a library.We now plan to develop a new technology based on the idea of minimising the volume of biological and chemical reactions further.Normally, each experiment in biology or chemistry is performed in a tube or multi-well plate. We now want to perform performed each assay in a separate microscopic droplet, with a volume one billion times smaller than a conventional assay.These droplets will be formed, manipulated and analysed in a microfluidic system, consisting of a network of microscopic channels through which the droplets will flow in a stream of oil.We aim to demonstrate their utility of this technology to search large numbers of compounds to develop new catalysts in directed evolution experiments.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'A genetic model for neurorehabilitation' (GEMiNI), addressing dissemination and exploitation.

assistant: **Impact**

Coordinated walking in vertebrates and multi-legged invertebrates such as the fruit fly Drosophila melanogaster is controlledby an evolutionarily conserved network capable to control movement in a fast, stable, and energy-efficient way. At the sametime, it provides the flexibility to adapt to changes in the terrain, load, and internal motor representations due to disease orinjury. Currently, the contribution of different brain structures responsible for the recovery process is only partially understoodand, importantly, the role of specific genes remains mostly elusive. Preliminary data shows that adult Drosophila flies inwhich the two middle legs were amputated improve their gait performance gradually over the course of a few days engagingin a more controlled gait. We also find that mutants for the learning and memory gene rutabaga lack any kind of short- orlong-term recovery. These results suggest that flies can readjust their motor circuitry upon injury and that a mechanism ofsynaptic plasticity might be involved.The overall goal of this proposal is to establish the fruit fly Drosophila as a genetic model for neurorehabilitation and recoveryafter amputation, which will allow the identification of new genes and mechanisms of motor plasticity. In order to carry outthese aims, I will take advantage of the sophisticated Drosophila neurogenetic toolkit that allows gene manipulation and theexecution of in vivo gain and loss-of-function experiments in a controlled number of neurons. In addition, I will use an adultfly walking assay that I developed during my postdoc, the FlyWalker system, which allows a detailed quantification of locomotor activity. Identifying genes and molecular components that affect the process of plasticity and motor adaptation will allow us to identify