RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Memory alloys for new structural' (1994-1998).

assistant: **Concept**

The objectives of MANSIDE, consisting in designing, implementing and testing new passive control devices, have been fully achieved.  SMA-based devices can provide performances at least comparable, but often better than current devices, plus special features as the re-centring capability, a high durability, a superior fatigue resistance.  This results in no need of maintenance along the entire structure lifetime, even after strong earthquakes, and makes the employment of SMA-based devices more convenient, from both a technical and an economical point of view, than the currently used passive control systems.  Since 1998 they are covered by an Italian patent.  A Project final workshop (Rome, 28-29 Jan.99: 200 participants of 10 countries), the diffusion of Project videos and workshop proceedings (about 1,000 persons reached) and the implementation of the proceedings and the 3rd yearly report into the DSTN-SSN Internet web site have ensured an adequate dissemination of Project results.Objectives and content In the last ten years the adoption of systems for the passive protection of buildings and infrastructures against vibrations of different source has been growing at an increasing rate, both for new constructions and for the retrofitting of existing ones, reaching the order of one thousand applications in the world. Even this large figure is anyhow negligible when compared to the global - present and future construction wealth, of several orders of magnitude larger, representing a virtually unlimited global market. Though, such growth is being strongly hampered by the limitations of the present technologies: for the different existing classes arise problems of ageing (e.g. for rubber components), of maintenance (e.g. for those based on fluid viscousity), of installation c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Dissecting the mechanism of DNA repair in human mitochondria' to be submitted under Horizon 2020.

assistant: **Abstract**

In mammalian cells genetic information is stored in two compartments: in the nucleus and in the mitochondria. DNA in mitochondria (mtDNA), just like in theIn mammalian cells genetic information is stored in two locations: in the nucleus and in mitochondria. DNA in mitochondria, just like in the nucleus, must be faithfully copied and mistakes (i.e. mutations due to exogenous and endogenous DNA damaging agents) lead to formation of DNA lesions. Persistence of these DNA lesions leads to genomic instability and human diseases like cardiovascular, skeletal muscular and neurological disorders, cancer as well as normal aging process. Mitochondrial DNA (mtDNA) is anchored to the inner mitochondrial membrane thus is in a close proximity to the electron transport chain and is subjected to a constant attack by reactive oxygen species (ROS), generated as byproducts of oxidative phosphorylation (OXPHOS). As a result mitochondria must have a robust DNA repair mechanism which becomes particularly important in non-dividing cells. It is accepted that DNA base excision repair (BER) pathway is a major defense mechanism against oxidative damage in human mitochondria. Aptly localized on mitochondrial inner membrane, mitochondrial BER enzymes: catalytic subunit of DNA polymerase γ (PolγA) along with its accessory subunit, DNA polymerase γ (PolγB), inner-membrane 5'-exo/endonuclease (EXOG), Apurinic/apyrimidinic endonuclease 1 (APE1) and Ligase 3 (Lig3) form a membrane-bound, high molecular weight, complexes called “mitochondrial repairosome”, capable of carrying out complete DNA repair. Although BER can be readily detected in mitochondria and major components have been identified, the spatial-temporal organization of mitochondrial repairosome and molecular mechanism by which mtDNA is repaire
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Model-based estimation of railroad wheel-to-rail profile change and contact forces' (DETECT4WE).

assistant: **Innovation**

The EU wants to encourage train travel due to the current climate crisis and innovations to the railway system are necessary. Because trains run around the clock in 23-minute intervals, it is difficult to monitor the status or the conditions of a railway equipment efficiently without interrupting railway operation and it only reduces the likelihood of its failure. DETECT4WE will offer a novel solution to help keep infrastructure safe. In this project, the condition of the tracks and the in-service trains are continuously monitored by smart sensors and the collected measurement data and safety analysis of trains are processed in real time. Therefore, a highly detailed forecast is ensured. This approach promises cost savings for vehicle manufacturers because of relatively inexpensive instrumentation techniques and shared computer analysis systems. And because more timely and accurate accident prevention will be available, train travel will become safer, leading to zero fatalities.The DETECT4WE project will be carried out by the experienced researcher who worked during her PhD thesis on the pure computational analysis of railway vehicle multibody dynamics and wanted to practice her research into applied railway engineering using experimental methods and make connections within railway industry.  She will collaborate with Prof. Jos L. Escalona at University of Seville, Prof. Zili Li at Delft University of Technology. Both supervisors have strong background in computational and experimental dynamics of railway vehicles and tracks. In the end, a final six-months non-academic placement will be carried out at the company ProRail Ltd. under the supervision of Prof. Rolf Dollevoet. The academic and non-academic stay will give her the unique opportunity of modelling, experimentall
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Fully robotic system for swapping electric car batteries within 3 minutes.' (POWERSWAP) under Horizon 2020.

assistant: **Objectives**

Our proprietary robotic technology can swap the 200 kilo car battery in a bit more than 2 minutes, saving vast amount of time and ensuring uninterrupted mobility. Batteries go to the battery storage where they can get suitable time for a harmonious charging at peak-off time. This lengthens their lifetime and puts much smaller pressure on the electric grid, allowing for the efficient management of power system and smart synchronization with distributed green energy resources (DERs) in power grid. Powerswap makes the bold step forward addressing challenges related to smart and clean e-mobility as charging time of batteries in battery storage can be flexibly adapted, minimizing additional pressure on power systems. Our automated batteries storages can also provide “grid balancing” services and return power to the grid at a time when managing the network is becoming increasingly complex as variable sources of wind and solar power grow. Our project will have a huge social added value by creating healthy urban environment and accelerating the development of clean transport systems based on electric cars. Powerswap will give the EU EV infrastructure a major boost and encourage new surges in EV transportation leading to definite elimination of combustion engines. We have engaged in the project well-known global market players: Renault (Renault Zoe), Sound Group (major supplier of batteries in China), Taxi Stockholm (will use our cars in the demonstration phase) and Didi (Chinese smart transportation company). The project will also have a vast impact on the applying SME and will stimulate its growth with a potential of reaching a turnover of €28M for in year 2024, and increasing employment by 40 jobs in the same year.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Uncovering the Kinship Matrix: A New Study of Solidarity and Transmission in European Families' (KINMATRIX), addressing dissemination and exploitation.

assistant: **Impact**

How do families mobilize to respond to their members’ needs? How do families transmit advantages and disadvantages within and across generations? Most of what we know about these questions is restricted to solidarity and transmission in the nuclear family – a small segment comprising only the closest kin. The project’s core concept – the kinship matrix – offers a much richer view of family members and family ties relevant to solidarity and transmission. It widens the lens to examine nuclear family ties in a larger pattern of relations that constitutes the immediate and extended family network spreading vertically and horizontally. Based on this concept, the project will achieve three objectives: to collect new comparative data on the kinship matrix in five European countries (Objective 1); and to use these data to conduct novel studies of solidarity (Objective 2) and of transmission (Objective 3) that break new ground in family research. The project comprises three subprojects, each dedicated to one objective. Subproject 1 will achieve Objective 1, collecting and preparing data on kinship ties that underpin all analyses on solidarity and transmission. The new comparative survey on the kinship matrix will be supplemented by further sources of population-scale data. Subproject 2 will achieve Objective 2, capturing solidarity in a multigenerational structure of immediate and extended kin. Subproject 3 will achieve Objective 3, capturing status transmission and behavioral transmission across a wide set of relevant kin. All subprojects will study the channels of solidarity and transmission, combining attribute data on status and behavior with relational data on the quality of kinship ties. The project will advance our understanding of the family as a unit of cohesion constit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Exploring the potential of snow data assimilation in forest areas'.

assistant: **Concept**

Despite its importance, snow water equivalent (SWE) monitoring remains an unresolved issue in modern hydrology. This is a consequence of the limitations of orbital sensors, the large spatial variability of the snowpack and the combined errors of meteorological forcings and numerical models. Snow data assimilation (SDA) of remotely sensed data into numerical models is one way to advance the estimation of SWE distribution in remote regions. However, implement SDA initiatives in forested areas is challenging, limiting the development of SDA initiatives in more than 20% of the Northern Hemisphere. The aim of this project is to train the candidate in sophisticated radiative transfer modelling and AI, to implement snow-forest interactions in data assimilation pipelines for a better understanding of snow freshwater resources. This main objective will be developed through the creation of an international network of experts, to train the researcher in different related topics. This includes Dr Jessica Lundquis (Outgoing phase host) from the University of Washington, an authority on forest-snow interactions, and Dr Simon Gascoin (returning phase host) from CESBIO (Toulouse, France), with long experience in multidisciplinary snow remote sensing. The results will be used to enhance the current capabilities of the MuSA tool, an open source and highly scalable data assimilation system developed by the researcher. The project will be the first effort to infer SWE in forest through SDA of spacial imagery, and therefore is of great interest for many stakeholders and scientists. The project is designed with an obvious focus on training the researcher in new techniques but also in soft skills thanks to the mentoring programs of both the University of Washington and CESBIO. The ultimate go
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Sharing Open Source Software Middleware to improve industry competitiveness in the embedded systems domain', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The SHARE project aims to facilitate open source software code sharing and utilisation within the embedded system domain, creating a nurturing environment for applications and solutions to be developed on OSS middleware, and paving the way for new business models and services. The focus of the project will be on:<br/>- Middleware for mission critical applications<br/>- Middleware for nomadic networks applications <br/>- Middleware for e-health applications<br/>The SHARE initiative will then broaden its scope to other sectors that could benefit of the usage of OSS middleware in the embedded system domain, providing the following functionalities/services: <br/>- The SHARE Web Based platform where OSS code will be uploaded and shared, together with any relevant information facilitating the usage and dissemination of such software<br/>- An Open Source knowledge framework which will act both as a knowledge collection methodology and a benchmarking tool. Adequate templates and benchmarking methodologies will be created by means of focused studies that will collect relevant assessment methodologies based on key parameters such as quality, security, interoperability, use of Open Standards and maintainability <br/>- Networking and awareness creation actions towards developers as well as end users in the embedded system community, including the organization of two International Dissemination Workshops that will serve as meeting events where stakeholders will be able to make networking, as well as present their concerns and achievements. <br/>The overall action will be industry driven, as far as the SHARE Consortium includes worldwide recognized industry leaders, as well as universities and leading technology transfer organisations. The strong link of the SHARE consortium with the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Blind channel estimation for spatial division multiple access in mobile communications systems' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

The increasing popularity of mobile communications is leading to the saturation of the available capacity of existing mobile communication systems (e.g. GSM). The expected shift from voice to multimedia communications will accentuate this problem enormously. Hence the capacity of mobile communication systems needs to be increased dramatically. The only dimension that has not been exploited to gain capacity is the spatial dimension. Indeed, multiple users can communicate simultaneously and on the same frequency band by distinguishing them according to their direction This is spatial division multiple access (SDMA). In order to realize SDMA in the presence of inter symbol interference due to multipath propagation, the spatial channel transfer matrix has to be known. Its straightforward estimation requires protocol overhead of which the relative importance increases drastically with the number of users served. We wish to develop blind techniques that arrive at estimating the channel without overhead, to make SDMA feasible.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Denox process for the refinery of the future' (DENOXPRO).

assistant: **Concept**

The scope of this proposal is the reduction of the NOx emissions from the regenerator of the Fluid Catalytic Cracking Unit (FCC). The innovative approach of the project is the design of novel deNOx additives that catalyze the reaction of nitrogen-containing reaction intermediates (NH3, HCN) formed during regeneration of spent FCC catalysts with NO formed by direct oxidation of the experiments. The physicochemical properties of the novel additives will be measured and mechanistic studies over the promising catalysts will be carried out. Superior performance of the new additives will lead to production of large catalyst quantities for pilot plant testing. Commercial scale tests will be carried out in 3 refineries using state of the art deNOx additives.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Advancing the non-invasive assessment of brain communication in neurological disease' (TrueBrainConnect) targeting Horizon 2020.

assistant: **Abstract**

Pathological communication between different brain regions has been implicated in various neurological disorders. However, the computational tools for assessing such communication from neuroimaging data are not sufficiently developed. The goal of TrueBrainConnect is to establish brain connectivity analysis using non-invasive electrophysiology as a practical and reliable neuroscience tool. To achieve this, we will develop novel signal processing and machine learning techniques that address shortcomings in state-of-the-art reconstruction and localization of neural activity from sensor data, the estimation of genuine neural interactions, the prediction of external (e.g., clinical) variables from estimated neural interactions, and the interpretation of the resulting models. These techniques will be thoroughly validated and then made publicly available. We will use the TrueBrainConnect methodology to characterize the neural bases underlying dementia and Parkinson's disease (PD), two of the most pressing neurological health challenges of our time. In collaboration with clinical experts, we will address practically relevant issues such as how to determine the onset of 'freezing' episodes in PD patients, and how to detect different variants and precursors of dementia. The outcome of TrueBrainConnect will be a versatile methodology allowing researchers, for the first time, to reliably estimate and anatomically localize important types of interactions between different brain structures in humans within known confidence bounds. The proposed clinical applications will improve our understanding of the studied diseases and will lay the foundation for the development of novel diagnostic markers for these diseases.


**Keywords:** Brain Connectivity; Electroencephalography; Magnetoence
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Characterisation of exocrine cells from adult rodent pancreas and their phenotypic plasticity in pancreatic pathology and regeneration' under Sixth Framework.

assistant: **Concept**

The adult pancreas consists mainly of exocrine acinar and duct cells, with interspersed endocrine islets. All these cells arise from embryonic protodifferentiated duct cells. In adult life, the exocrine cells retain phenotypic plasticity. In pancreatic pathology and regenerative conditions, acino-ductal metaplasia has been shown. A major problem in tackling the relationship between these cell types is the lack of stage-specific cell differentiation markers for study which - in turn - hampers the development of reliable genetic-based cell lineage-tracing studies.   This project aims at developing new insights into the acinar versus ductal phenotype on one hand, and the differences between embryonic duct cells, normal adult duct cells, and metaplastic exocrine cells on the other hand. The transcriptome of these cell types will be analyzed using laser capture microdissection and microarrays. In addition, we will explore the role of Notch signalling as a cell fate decision maker in exocrine cell phenotypic changes, during pancreatic pathology and endocrine cell neogenesis. Notch will be overexpressed in normal adult pancreas via virus-mediated gene delivery targeted to the acinar or duct cell population. Effects on the exocrine phenotype will be evaluated.