RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Feasibility study for an advanced systematic documentation, information and communication tool in the field of ethical issues in science, research and technology' (FASTER) under Sixth Framework.

assistant: **Objectives**

An adequate culture for ethical and legal judgment formation in science, research, technologies and their applications can only be developed if those involved have access to reliable, comprehensive and up-to-date information and adequate communication. T herefore there is a demand for an infrastructure to create a systematic documentation, information and communication tool in the field of ethical issues in science, research and technology (ASTER) including multilingual access to information e.g. on topi cal debates, legislation, codes of conduct and contested issues taking place in the different European countries. The foundations for such a system have already been laid in a number of projects funded by the 5th FP EU (esp. EURETHNET). The feasibility study which is the object of this proposal will have to evaluate a new type of infrastructure which covers not only the field of bioethics but the whole range of ethical issues in research and technology in Europe. More specifically, the feasibility stud y will analyse the various areas concerned and will identify the potential users and their specific needs including the NAS. It will scrutinise the existing networks and their information resources including their demands to be connected with other netwo rks in a network of networks. Therefore the feasibility study will investigate and evaluate the various methods and techniques which ensure the structure and management of the relevant knowledge and information content in relation to the thematic coverag e, the development of adequate communication links as well as the support for an appropriate integration of networks and established institutional providers in the fields mentioned above. The result envisioned will provide criteria and scenarios to esta blish and operate
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'C9orf72 repeat expansion in FTD/ALS - from mechanisms to therapeutic approaches'.

assistant: **Innovation**

Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are fatal neurodegenerative diseases with overlapping genetics and pathology. The most common known cause is expansion of a GGGGCC repeat in the first intron of the gene C9orf72. I discovered that the repeat region is translated in all three reading frames into aggregating dipeptide-repeat (DPR) proteins despite its intronic localization and lack of an ATG start codon. DPR aggregates outnumber the previously identified TDP-43 inclusions in the hippocampus, cortex and cerebellum. Some patients exclusively show DPR pathology, strongly suggesting DPR production is a key pathomechanism in C9orf72 mutation carriers.  However, we know next to nothing about the mechanisms of translation, toxicity, aggregation and clearance of DPR proteins. With this grant I will characterize this unusual pathomechanism in detail.First, I will generate monoclonal antibodies for a comprehensive analysis of all DPR species to determine the best pathological correlate of disease progression. Insights from patients will drive mechanistic studies and will help to identify therapeutic targets within the DPR cascade. Second, I will develop cell culture models to identify the molecular pathways that determine the expression, toxicity and aggregation of DPR proteins. These models will be used to identify drugs that block all steps of the DPR cascade in pilot screens. Third, I will create transgenic mouse models expressing DPR proteins to rigorously validate the DPR hypothesis by comparing pathology and clinical symptoms of transgenic mice and human C9orf72 patients. Finally, these mouse models will be used to test promising compounds identified in cellular models in prevention and treatment trials. Moreover, I will analyse whether pas
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Spatial resolved potential distribution in polymer-blend photovoltaic structures' (1998-2002).

assistant: **Concept**

Determination of the complete potential profile across typical polymer-blend structures under bias and with high spatial resolution for understanding of the relationship between interface electronic structure and electrical behavior in organic thin film devices
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The use of glazing traditions to examine the dynamics of interaction between cultures in contact: A case study of Cypriot glazed wares from the 11th to 17th centuries AD' (GLAZE) under Horizon 2020.

assistant: **Objectives**

GLAZE seeks to investigate the suitability of using glazing traditions to reflect the dynamics of interaction between cultures in contact. Cypriot glazed ceramics dating to the 11th and 17th centuries AD, a period when fundamental socio-political changes occurred in the region, will constitute our principal case study. GLAZE has two key research questions:·   What are the variations in the glazing traditions that existed in Cyprus during the 11th to 17th centuries AD?·   To what extent did the interaction between cultures in contact stimulate the transmission of technological knowledge and practice in glazing traditions?We have devised a cutting-edge cross-disciplinary approach by integrating material science, archaeology, data management and analytics, and anthropological theory. Thin-section petrography, WD-XRF, SEM-EDS, and ICP-MS will be used to reconstruct different aspects of glazing traditions. A database for glazing traditions will be developed to explore the temporal and spatial trends in the development of glazing traditions in the region and their relation to the broader medieval and post-medieval glazing traditions. The cultural transmission of technological change will be applied to interpret the resultant patterns in order to shed light onto the dynamics of interaction between cultures in contact.GLAZE is the first project dedicated to the systematic study of glazing traditions in Cyprus, and indeed in the eastern Mediterranean. Given the ubiquity of glazed wares in the medieval and post-medieval worlds, the results derived from GLAZE will create a new dimension into understanding the complexity of interaction between cultures in contact, especially the ones that are not recorded in written sources. This project will benefit from the applicant’s cross-disc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Nanostructured materials: atomic transport properties for the synthesis and characterization of novel soft and hard magnets' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Applicants are invited for a 12 month term as a research fellow supported by individual fellowships of the Marie Curie fellowship scheme. The successful candidates will be involved in the synthesis and processing of novel nanostructured materials and composites for soft magnets (Finemet-type) and hard magnets (FeNdB-type), as well as with the investigation of their microstructure, magnetic, and diffusional properties. The gas-phase condensation technique with subsequent compaction under high pressure is used for the production of highly dense nanocrystalline materials. Basic material characterization will be carried out by x-ray diffraction, differential scanning calorimetry, optical microscopy, and atomic resolution electron microscopy (HRTEM). In addition, several instruments for characterization of magnetic materials are available. These experimental techniques allow the investigation of a number of phenomena, including: order-disorder transformations, transformation kinetics, phase transitions, and relaxation processes. Furthermore, diffusion studies using the radioactive tracer technique are carried out to study the atomic transport properties in nanocrystaline structures, which deviate significantly from bulk and grain boundary diffusion processes studied so far. The candidate has to satisfy the basic criteria of the training scheme as outlined on the Marie Curie Host Fellowship Web site http://cordis.europa.eu/improving. As the fellowship forms part of a higher degree project, the candidates should be registered full-time Ph.D. research student in a well-recognized institution of the EC. The research interest of the candidates should be in at least one of the following fields: solid state physics, materials science including synthesis and characterization of mate
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Rough paths and stochastic partial differential equations' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Partial Differential Equations (PDEs) play an essential role for mathematical modelling of many physical phenomena, and the literature devoted to their theory and applications is enormous. Stochastic Partial Differential Equations (SPDEs) started to appear in the mid - 1960s. They were motivated by the need to describe random phenomena studied in the natural sciences such as control theory, physics, chemistry and biology. They are used, for example, in neurophysiology, mathematical finance, chemical reaction--diffusion, population dynamic, environmental pollution and nonlinear filtering.Another source was an internal development of analysis and the theory of stochastic processes. The recent theory of rough paths provides a framework for interpreting and solving ordinary differential equations for irregular, deterministic paths that encompasses such examples.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'A global sudy of 2d and 3d statistical deformable models'.

assistant: **Concept**

Research objectives and content One of the principal aims of image analysis in computer vision is shape modelling. The principal role of a model is to facilitate robust automatic interpretation even in noisy or cluttered images, or in images where parts of the objects of interest may be occluded. In the last few years, there has been a growing interest in deformable models for the analysis of images of objects whose appearance can vary continuously, in particular in the context of medical imaging, where organ shape may vary considerably through time and between individuals. Among several models which have been proposed, statistical deformable models seem to be more robust, because they are able to support a considerable shape variability but only deform in ways which are characteristic of the objects they represent. Their study is the topic of the proposed project. Specifically, the objectives of this research will be the following: further investigation into two existing methodologies, namely Cootes' and Grenander's deformable templates, in order to improve their efficiency; building of a common probabilistic framework for these two approaches; development of a new three-dimensional statistical model and finally, development of a tool based on the Bayesian paradigm for the fusion of different informations extracted from different modalities Because of the ability of statistical models to classify families of objects into subgroups according to shape variability and to identify abnormal cases, their application in the medical imaging field, especially with three-dimensional images, is very promising. Within the context of this project, we will particularly focus on the study of shape variability of the cardiac left ventricle from various modalities (Nuclear Medicine, Ul
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'A Network for Industrially Contaminated Land in Europe'.

assistant: **Concept**

The objectives of the network are: 1. To provide a European forum for the dissemination and exchange of scientific and technological knowledge and ideas relating to all aspects of contaminated land arising from industrial activities. 2. To promote coordinated, multi-disciplinary, collaborative research that will enable European manufacturing and processing industry to identify, assess and manage contaminated sites more efficiently and cost effectively. 3. To inform relevant EU and Member State RTD Programme Planners of needs and priorities for future research and to improve the synergy and coordination of research being carried out in EU programmes and other initiatives at the European and Member State levels.The network will be divided into four Working Groups, each addressing aspects of the subject:  WG1 Site Assessment and Characterisation  WG2 Contaminant Behaviour and Risk Assessment  WG3 Control Methods  WG4 Measurement & Monitoring  The Working Groups will be academy-led and coordinated by an industry-led Steering Group which will include  representatives of the EU Environment and Standards, Measurements & Testing RTD Programmes.  The network's objectives will be achieved through a series of structures trans-network scientific conferences,  workshops organized by the Working Group and a network newsletter. A Scientific Advisory Group will be  formed to represent consensus views on priorities for the future research to the Commission:  -the remediation of contaminated sites.  -the effect of contamination on the diversity of organisms that can degrade organohalogens.  -availability of new cultures for application in environmental cleanup processes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Multi Purpose Mobile Robot for Ambient Assisted Living', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Due to increasing mobility and the ageing society the demand for care will increase significantly, leading to high costs and unrealistic manpower demands. Florence will alleviate this by keeping elderly independent much longer by providing care and coaching services, supported by robots. This will greatly improve the efficiency in care and reduce costs. The second problem addressed by Florence is the acceptance of robots by elderly. For this purpose the project adopts a user-centric approach, by starting with focus-group sessions, having lab-tests in the OFFIS IDEAAL lab, and finally evaluating the services in the Granada AAL living labs. The Florence consortium contains partners from the complete value chain: robot vendors, care providers, and consumer electronics vendors. The consortium positions the service robot as a consumer device, supporting various lifestyle services. In particular the following services will be evaluated in the project: * Social Connectedness: provide access to the social networks, including web-2.0 and synchronous communication tools * Coaching: give feedback on specific activities like physical exercises, and advise on activities of daily life * Care support: log care-related activities at home that are shared among professional or volunteer caretakers. * Safety: use the robot as additional ears and eyes in comfort or safety situations, controlled by service providers or the elderly users.In order to support this multitude of services, the Florence system is based on a service-oriented architecture that provides programmatic interfaces towards the (interaction) capabilities provided by the robot, the home, and remote service providers. Such integration will effectively turn the Florence system into a generic platform for home-services, integr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Viral hepatitis surveillance in mediterranean countries' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

In order to determine the public health impact of hepatitis C (HCV) and E (HEV) in Mediterranean countries(MC) (Algeria, Egypt, Palestine Authority, Tunisia and Turkey), research groups from MC and collaborating. countries (Belgium, France, Germany, Netherlands) will 1/develop a sentinel surveillance system to monitor the changes in HCV infection prevalence and genotype distribution 2/establish a community based cohort for longitudinal surveillance of HCV infection incidence and risk factors, morbidity and mortality in the country with the highest HCV prevalence (Egypt) 3/estimate, through mathematical modelling, the national and regional impact of HCV infection in MC 4/determine the role of HCV and HEV in the occurrence of acute andfulminant hepatitis S/improve the methods of serological diagnosis of HCV and HEV genotypes circulatingMC 6/monitor early immunological response to HCV and HEV 6/identify animal reservoirs for HEV; investigate the genomic patterns of animal versus human strains. These approaches will allow to understand better the epidemiology of HCV and HEV and contribute to the optimisation of prevention strategies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Promoting and reinforcing international RTD cooperation between Europe and Brazil and Cuba' (PROMINENCE).

assistant: **Concept**

The proposed project is designed by a consortium composed of European, Brazilian and Cuban institutions to provide practical and methodological support to the objectives of the ALCUE Meeting 2002 and INCO programme with regards to two countries of the re gion - Brazil and Cuba. That is why the main objective of the proposed project is to strengthen and widen research collaborations between the European, Brazilian and Cuban research communities in the light of the new cooperative opportunities offered by FP6 and INCO, in particular, and, by this, to contribute towards achievement of the objectives of European Research Area. The project objective will be achieved by implementing a coherent set of activities which will include the following: 1. The Study w hich will map the research landscape in Brazil and Cuba specifically in the context of research priorities with the aim to identify the most promising themes for cooperation, will gather and generalize best practices and experiences of previous INCO proj ects to improve quality of future collaborations, will find synergies between different funding schemes available for cooperation; 2. Raising awareness and dissemination strategy targeted at research communities in Europe and in Brazil and Cuba. These ac tivities will include thematic seminars in Brazil and Cuba, promotion of cooperative opportunities at the selected European events and through various channels of dissemination; 3. Sustainable and competent support to and facilitation of future research p artnerships by training the local experts in the field of innovation and project management. Successful implementation of the project will lead to increasing number of joint research projects, engaging wider research communities both in Europe and in th e partner countr