RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Boron-boron multiple bonding' in the context of a Horizon 2020 call.

assistant: **Objectives**

Multiple bonding between atoms is immensely important to chemistry, biology, physics and their associated industries; multiple bonds are both ubiquitous in everyday products and extremely useful functionalities for effecting chemical transformations. While very common with the elements carbon, nitrogen and oxygen, multiple bonding is in comparison extremely rare with other elements. Multiple bonding between heavier elements of the main group of the periodic table becomes less favourable the heavier the element becomes. However, this does not explain the relative paucity of multiple bonding with boron, which is immediately to carbon's left on the periodic table. In particular, isolable, stable compounds containing multiple bonds between two boron atoms are extremely rare, and until 2007 only a handful of charged examples existed.A revolution in this field has recently been witnessed with the syntheses of the first neutral compounds with boron-boron double bonds, diborenes, and the first compounds with boron-boron triple bonds, diborynes. The first neutral diborenes were prepared in 2007, however, we have recently developed a number of rational, selective and more general routes to these compounds. The first diboryne compounds were prepared by our group in 2012. The significance of these two families of molecules is not only their unusual multiple bonding but also the extremely high electron density on the boron atoms, an unusual situation for an element that is known for its electron-poor character. This high electron density leads to strong boron-based nucleophilicity and extremely high reduction potentials – both highly novel phenomena.This proposal aims to: (A) comprehensively explore the syntheses of these unique compounds and the limits thereof, and to (B) exploit t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Regional, National and European Support for Photonics Innovation Clusters enhancing SMEs Innovative Potential' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

RespiceSME will reinforce the innovative capacity of Europe’s photonics SMEs, clusters and national platforms by stimulating increased collaborations in and beyond photonics. RespiceSME proposes new approaches for stronger innovative effectiveness using a 3-dimensional approach, led by an experienced, representative, interdisciplinary team. In the 1st dimension, the project will develop a measure of the innovative potential for Photonics SMEs; the index will be integrated with a methodology for auditing innovative SMEs. Coaching on these tools will lead to their diverse application; enhancing the innovative capacity of 30+ photonics SMEs is targeted in the project. In the 2nd dimension, RespiceSME will develop new approaches for analysing value chains in close collaboration with clusters and national platforms. Empowering photonics SMEs and cluster managers to undertake early stage analyses of value chains, in the 3 separate domains of commercial intensity, technology readiness and innovative potential, will lead to more effective penetration by European photonics SMEs in global non-photonics sectors. Approaches will be demonstrated by new business collaborations in photonics, and using photonics, in manufacturing, energy and transport sectors. Harnessing the full innovative capacity of the European photonics infrastructure is the objective of the 3rd RespiceSME dimension. Best practices for enabling photonics SMEs access European and regional infrastructures, harness educational and training programmes aligned with their specific needs, determine next generation regional innovative smart specialisation strategies, and be better resourced by efficient public and private financial supports, can be transformative. RespiceSME will disseminate results using face to face and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Positive health effects of the natural outdoor environment in typical populations in different regions in Europe (PHENOTYPE)' in the context of a Seventh Framework call.

assistant: **Objectives**

Indications exist that close contact with nature brings benefits to human health and well-being. The proposed work will investigate the interconnections between exposure to natural outdoor environments, in both rural and urban settings, and better human health and well-being in the North West, South and East of Europe. The project will explore the underlying mechanisms at work (stress reduction/restorative function, physical activity, social interaction, exposure to environmental hazards) and examine the health effects (general health and well-being, mental health/neural development, stress, cardiovascular, cancer and respiratory mortality and morbidity, birth outcomes and obesity) for different population groups (pregnant women and/or foetus, different age groups, socio-economic status, ethnic minorities and patients). We will use conventional and new innovative high tech methods to characterize the natural environment in terms of quality and quantity. Preventive as well as therapeutic effects of contact with the natural environment will be covered. We will address implications for land-use planning and green space management.  The work will produce more robust evidence base on links between exposure to natural outdoor environment and human health and well-being, and a better integration of human health needs into land use planning and green space management in rural as well as urban areas.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Objects of Contention: Art and Craft in the French Penal Colony of New Caledonia' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

In recent years, the creative practices of individuals subjected to various forms of captivity have become a vibrant field of study known as carceral aesthetics. However, despite the long and far-reaching history of penal transportation, the art and craft produced in penal colonies around the world have received little attention. My project, Objects of Contention: Art and Craft in the French Penal Colony of New Caledonia (ObCo), will contribute to these debates and offer new perspectives on the relationship between creation and oppression in colonial New Caledonia (1853–1946). Yet this research will not solely focus on the art and craft produced by some of the 30,000 common law prisoners, repeat offenders, and political prisoners transported to the Pacific archipelago in an effort to rid metropolitan France from its so-called dangerous class. It will also include the study of the creative practices of the Kanak, the Indigenous people of New Caledonia whose land France seized to establish the colony and whose history has typically been told in isolation. In addition to facing similar forms of detention, exile, and extractive labor, ObCo will show how the stringent control measures experienced by the Kanak and their progressive confinement to reservations expand the study of art and captivity well beyond the confines of the prison’ walls. In doing so, ObCo will not only fill a critical gap in the history of carceral aesthetics but also deepen our understanding of the historical conditions that fuel New Caledonia’s current waves of political and civil unrest. I will pursue this interdisciplinary research project under the guidance of Benoît Trépied, an anthropologist specializing in the history of citizenship in New Caledonia, in program co-led by Prof. Trépied called “Eth
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'An Open, Ubiquitous and Adaptive Chronic Disease Management Platform for COPD and Renal Insufficiency' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Chronic diseases are those that occur across the whole spectrum of illness, mental health problems and injuries. Management includes medication and/or lifestyle changes such as diet and exercise. At the same time, it should be noted that chronic diseases may get worse, lead to death, be cured, remain dormant or require continual monitoring. CHRONIOUS primary goal is to define a European framework for a generic health status monitoring platform schema addressing people with chronic health conditions. This will be achieved by developing an intelligent, ubiquitous and adaptive chronic disease platform to be used by both patients and healthcare professionals. CHRONIOUS addresses a smart wearable platform, based on multi-parametric sensor data processing, for monitoring people suffering from chronic diseases in long-stay setting. It is constantly monitoring their activity using audio observation methods and activity sensors while at the same time tracking their medical condition via vital signs sensors. Any trait of abnormal health status and possible alerting incidents are detected by CHRONIOUS Intelligence.  The system generates alerts in case of invalid medical data or if current activity and behaviour lay outside the well established activity patterns and locomotion behaviour. Furthermore, CHRONIOUS objective is to face Europe's challenge for delivering quality healthcare to all its citizens by offering a ubiquitous and more personalised care solution that addresses the user needs, personal data security, confidentiality and privacy of information and all that at an affordable cost. Our proposed solution will be applied to the chronic diseases of Chronic Obstructive Pulmonary Disease (COPD) and Chronic Kidney Disease (CKD) and Renal Insufficiency.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Health Care Reform: the iMpact on practice, oUtcomes and costs of New roles for health pROfeSsionals'.

assistant: **Concept**

The proposed research responds to the call for research into the ‘Quality, Efficiency and Solidarity of Health Systems’. European countries are reforming their health systems to improve health care delivery. One of the ways they are doing this is by changing skill mix within teams delivering health services: extending the roles of existing health professions and introducing new ones. This project will undertake a systematic evaluation of the impact of these ‘new professional roles’ on practice, outcomes and costs in a range of different health care settings within European Union and Associate Countries. It will detail the nature, scope and contribution of the new professional roles, evaluate their impact on clinical practice and outcomes, and identify their scope to improve the integration of care. It will conduct economic evaluation to identify the cost effectiveness of the new professional roles, identify optimal models for delivery of health care and the consequences of these for   management of human resources and workforce planning. Study design is cross-sectional and multi-level. A mixed methods approach will combine analysis of routinely collected data and primary data generated through interviews and questionnaires to health professionals, managers and patients. Data analysis will employ multi-level modelling techniques.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'ENVISAGE (Development of Environmentally-friendly Innovative Solutions for Affected Grounds and Ecosystems)' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

In line with our growth strategy, INOQ is looking for an innovation associate to lead our business expansion project into the soil remediation market in Europe. With more than 20 years of experience, our company INOQ is a leading developer of mycorrhiza products used as microbial biostimulants for reforestation, food production, horticulture and others. With ENVISAGE we will provide mycorrhizal fungi to soil remediation companies as a complement and/or alternative to current remediation techniques for contaminated or affected groundsDuring the last decades, governments and private institutions have stressed their interest towards substitution of ecologically unfriendly and expensive remediation techniques with new forms of bioremediation. Given its relevance to our life, the governments and private actors from the EU member states have incurred in large amounts of soil remediation related expenses during the last years (more than €31 Billion from 2000 to 2010). To date there are many laboratory applications of mycorrhizal fungi on soil remediation, but no commercial applications in Europe. Therefore we identify our competitive advantage given our technical and commercial experience with similar applications. Based on our preliminary market analysis and based on advisory from industry experts, this market would represent for INOQ a business with an annual revenue value of at least €5 Million during the first 3 to 5 years. The envisaged profile has been considered to combine complementary skills and expertise. The innovation associate will use her/his research and qualitative/quantitative data analysis skills, as well as her/his bioscience and technical background to connect the market and industry related knowledge to our biotechnology. The incumbent will have a strategi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Generation and analysis of a domain based interaction map of C. elegans early embryogenesis' (2002-2006) under Sixth Framework.

assistant: **Objectives**

Macromolecular interactions, such as those between proteins, form the basis of all biological activity. Here, we propose to map the interactions between 800 proteins involved in early embryonic development of the nematode Caenorhabditis elegans. These proteins are involved in core processes common to all multicellular organisms. To generate the network, a novel application of the yeast two-hybrid system will be used, that yields several improvements compared to current interaction datasets. First, it will lower the false negative rate, increasing the fraction of interactions identified. Second, it will identify the domains required for each interaction. Most protein interactions occur between specific protein domains. For an accurate representation of interaction networks, this information should be captured. It will enable us, for example, to know whether two interactions may take place simultaneously, or are mutually exclusive because they are mediated by the same domain. Finally, the domain interaction map will be integrated with existing phenotypic characterizations and expression profiles to be able to better predict the biological functions of the proteins in the network.The resulting combined network will be used to gain a better understanding of multicellular development. We are using C. elegans as a model system because it is a relatively simple, tractable multicellular organism, and powerful genetic tools are available to study components of interaction networks in vivo. We will focus on candidate novel components involved in asymmetric cell division and polarity establishment, and on proteins with human homologs that are implicated in disease. The interaction network will also be publicly available. Because of the conserved nature of the proteins involved, th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Birthing Abolition: Reproduction and the Gradual End of Slavery in Brazil' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

BIRTHBRAZIL is an interdisciplinary project that will analyze how enslaved women’s reproductive trends and practices shaped the gradual abolition of slavery in the middle to large plantation holdings of Rio de Janeiro, Brazil from 1850 (the definitive end of the country’s slave trade) to final abolition in 1888. The project aims to contend that the struggle to end slavery was intimately entangled not only with elite understandings of slave reproduction but also with enslaved women’s own agency. To do so, it examines demographic trends among the enslaved population, elite views of enslaved women’s reproduction, and enslaved women’s own reproductive practices and agency. Like most Atlantic slave societies, the Brazilian slave population was reproduced through imports and not natural growth. Historians have argued that for 19th-century Rio de Janeiro state, harsh labour regimes and disease caused negative growth rates, dismissing the idea of “reproductive resistance”—the female enslaved practices of abortion and infanticide as purposeful attacks on the institution of slavery—popular in theories on Caribbean and US slavery. While enslaved women’s fertility control may not have caused negative population growth in 19th-century Rio de Janeiro state, BIRTHBRAZIL hypothesizes that enslaved women’s practices of fertility control played an important symbolic role in how elites understood and approached slavery itself. The findings of BIRTHBRAZIL are expected to demonstrate that enslaved women’s fertility control, both real and imagined, created the opportunity for abolitionists to implement the legal framework that abolished slavery. In doing so, the project provides historical background to current-day debates on reproductive rights, women’s health, and gender equality. The resu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The identification, characterisation and exploitation of novel Gram-negative drug targets' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

An ambitious long-term programme of multidisciplinary research with two closely linked objectives is proposed to support antimicrobial drug development. Firstly, to advance understanding, at the molecular level, of fundamental and important aspects of the biology of Gram-negative bacteria using the important pathogen model Pseudomonas aeruginosa. Secondly, and most important, to exploit our discoveries and develop ligands and inhibitors (hit and lead compounds) with the potential to underpin the discovery of improved therapies for Gram-negative infections. The research covers five distinct areas, or work packages. (WPI) The experimental validation and therefore identification of novel targets by gene knockout in P. aeruginosa. (WPII) Cloning, characterisation, biochemical and structural biology, of the novel targets. (WPIII) A directed, search for ligands/inhibitors, exploiting data from WPI and WPII, for these validated antimicrobial drug targets by virtual screening (VS) and assessment of druggabilty, high-throughput screening (HTS) of a carefully prioritised subset of targets. (WPIV) The characterisation of the interactions formed between the drug target and the ligand/inhibitor by biochemical and crystallographic study, computational modelling and then design and modelling to enhance binding properties. (WPV) The initial biological testing for efficacy against Gram-negative bacteria.