RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Trends in hospital admissions for lower extremity amputations in people with and without diabetes in England, 1996-2005'.

assistant: **Concept**

The prevalence of diabetes mellitus is growing at epidemic proportions worldwide. Considering the steady increase of the diabetic population, the prevalence of diabetes-related complications will continue to rise. Foot disorders are a major source of morbidity and mortality and account for more hospital admissions than any other long-term complication of diabetes. Up to 20% of total expenditure on diabetes might be attributable to diabetic foot. The most costly and devastating end-point of diabetic foot problems is lower extremity amputation (LEA). Individuals with diabetes have a 15 to 40 increased fold risk of LEA when compared to the general population with approximately half of all persons undergoing nontraumatic amputations having a diagnosis of diabetes. Appropriate multidisciplinary care to diabetic foot disease has been shown to reduce the incidence of LEAs by up to 78%. In Europe, a reduction in LEAs related to diabetes of at least 50% within 5 years was a declared aim of the St. Vincent Declaration and the US Government has set a target of reduction of 40% by the year 2000. There are only very few population-based studies available on the incidence and temporal variations of nontraumatic LEAs in Europe. Standardised, population-based data on LEA associated with diabetes are urgently needed, if these targets are to be achieved. The purpose of our study is to use national hospital admission data from all NHS hospitals in England from 1996 to 2005 to 1. provide standardized, population-based data on LEA associated with type 1 and type 2 diabetes; 2. evaluate changes in LEA rates in people with and without diabetes; 3. examine diabetes-associated LEA rates by age, gender and social deprivation to identify populations at risk; 4. analyse length of hospital stay (LO
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Solubility of Aerosol Iron in Open-ocean Seawater' under Seventh Framework.

assistant: **Concept**

The distribution of iron in the oceans is known to have a significant impact on carbon and nitrogen biogeochemical cycles and climate variability due to its role as a growth limiting nutrient for phytoplankton. The principle mechanism for iron transport to remote open ocean surface water is via the atmospheric transport of aerosol material. Hence an accurate understanding of the controlling variables for dissolution of aerosol iron in seawater is required to advance and improve global biogeochemical models. The aim of the proposed work is to conduct a rigorous study of aerosol iron dissolution in seawater by mimicking the conditions and variables of the air/sea interface that will affect the process. The study will test the hypothesis that the physico-chemical nature of seawater controls this dissolution process rather than the nature of the aerosol deposited. To address this, ship-board and laboratory dissolution experiments will be conducted following the collection and characterisation of aerosol and seawater samples from the Bermuda Atlantic Time Series region. The project will be based at the Bermuda Institute of Ocean Sciences (BIOS) and at the University of Plymouth (UoP) host institutions. The collaborative work will benefit the EU scientific community and strengthen the researcher’s profile by offering high level training in atmospheric sampling and handling and a variety of analytical techniques for the determination of dissolved iron species in seawater. It will also allow continued and frequent access to open ocean seawater and aerosol samples as well as interdisciplinary training in meteorology, oceanography and remote sensing. The results from the study will further contribute to the international scientific community by better constraining iron transport
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Activation and switch of fates in T lymphocytes.' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Antigen-stimulated naïve CD8+ T cells proliferate and differentiate into effector and memory cells. Whereas effector T cells remove infected or cancerous cells, memory T cells protect the organism from re-infections. Despite decades of research, the challenging central questions of how naïve T cells form diverse progeny and what drives the differential response of naïve and memory T cells to infection remain unanswered, largely because of lacking experimental tools.The goal of this project is to generate a comprehensive model of cell-fate choices of naïve and memory CD8+ T cells in vivo. We will achieve this by addressing three complementary specific objectives:1) To understand the early and late fate choices in naïve T cells.2) To uncover differences between naïve and memory T-cell responses and fates.3) To identify the role of proximal protein kinases LCK and FYN in T-cell fate choices.We will pursue these aims using a combination of experimental immunology and systems biology. We used the synergy between novel genetic models and single cell atlases (i) to characterize an unprecedented transient stage of activated T cells, (ii) to determine the early gene expression signatures and fate choices of in vivo activated naïve and memory T cells, and (iii) to observe that LCK secures memory T-cell formation. These tools and findings offer us novel perspectives to tackle the challenging objective in its full complexity. We will develop additional unique experimental models coupled with innovative in-silico techniques to uncover the cellular and molecular mechanisms underlying diverse fate choices of particular T-cell subsets and to narrow the gap between mouse and human immunology.Overall, this project has the ambition to resolve long-standing fundamental questions in immunol
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Capturing and adding value to CO2 & hazardous waste to produce valuable aggregates for construction' (Carbon8) targeting Horizon 2020.

assistant: **Abstract**

Carbon8 has developed Accelerated Carbonation Technology, ACT, a controlled, accelerated version of the naturally occurring carbonation process. It can be described as a CO2 capture and utilisation, or ‘CCU’, technology which captures CO2 to create a valuable, safe, carbon neutral or negative end-product which can be used as an aggregate by the construction industry. The technology is applicable to hazardous waste from industries including cement, steel and Energy from Waste. These wastes otherwise represent a problem for the waste producer and typically require pre-treatment before transportation to landfill – at a cost of up to 150 Euros per tonne.Carbon8’s technology has already been successfully deployed, under license by a waste management company, at large scale. This Phase 1 Project focuses on the identification of markets and suitable end-products for a small-scale version of the ACT technology - identified as more suitable to customer needs. The compact, containerized processing plant can be integrated into existing industrial processes, utilising CO2 contained in flue gas to treat the industrial waste. It represents a circular economy solution to both industrial waste and CO2 emissions. Carbon8 estimates that around 20% of the EU’s 143 million tonnes of reactive waste might be available. These waste streams would have the potential to capture 3.5 Mt of CO2 /year. There is interest from major cement producers: Heidelberg, Lafarge, CRH, and Cemex and from EfW operators, particularly in northern Europe where disposal options are limited and costs highest.By deploying smaller scale units with single waste streams, there is scope to fine tune the end product, an aggregate for the construction industry, with potential to ‘reverse-engineer’ a premium aggregate which
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Novel Injection Moulding Processing for the Production of Low Density Foams based on Innovative Granule Technology'.

assistant: **Concept**

Our concept is to enable the production of high quality foams from engineering grade thermoplastics using existing injection moulding and extrusion equipment installed in our SME communities. We propose the creation of a novel polymer processing technology. We will develop the ability to foam engineering grade thermoplastics without the need for chemical blowing agents or speciality moulding equipment. Our technology offers many advantages for SME injection moulders & extruders in sectors such as aerospace, automotive and construction. We will: • Eliminate the need to invest in expensive processing machinery to make foam parts • Eliminate the need for chemical blowing agents • Reduce material consumption • Reduce energy consumption through lower process temperatures • Produce low density, consistent foams with excellent mechanical properties • Reduce part cost and finishing operation requirements • Increase manufacturing flexibility We have selected engineering grade thermoplastics, which will be saturated with nitrogen gas at temperatures above Tg, where diffusion rates of gas within the polymer are significantly increased. The granules will then be cooled below Tg, ‘trapping’ the nitrogen molecules within. The granules will be packaged and shipped to SME moulders for use in standard moulding machines. During processing, melting of the polymer will release the trapped nitrogen, producing foam in the moulding machine. We will develop our understanding of melt processing technology to ensure optimum processing speed, density and mechanical performance. Initial trials have already indicated the potential of this process but the technology needs considerable further development for successful commercialisation. We strongly believe that our technological breakthroughs will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Solar control - integrated approach to solar control techniques' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

A major source of the differences in the evaluation of the summer thermal behaviour of buildings and the strong dissatisfation of end-users is evident in the lac of knowledge on the performance parameters / algorithms utilised for the calculation of shading effects. In fact, they do not take into account direct, diffuse and reflected radiation as well as the radiative and convective heat transfer. Furthermore, the development of appropriate testing procedure for assessment of the overall performance of Solar Control devices has received much the same scarce amount of attention. Although the scope of CEN TC 89 WG6 activities and WG7 Ad Hoc Group on Solar and Light Transmission" deals strictly with the issues regarding the properties of Shading Devices, they pointed out a distinct lack of technical background in the field. Furthermore the shading device sector is widely dispersed, with small and medium sized companies, often lacking R&D laboratories and without adequate support for the investigation and characterisation of the performances of their products. In consequence, it exists a further definite necessity of investigations at international and publicly funded level of the performance of shading devices in order to overcome the existing lack of support towards industry and final user, thus improving the dissemination of knowledge and the effectiveness of the application of these techniques. Specific objectives of this proposal are: 1) Developing new technologies and control devices directed to smart components for integration into the building envelope, with special intention on their impact on energy consumption and improvement of the indoor comfort as well. 2) Characterising the integrated performances of the most interesting shading devices (external, interpane a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Interventional SPECT/CT for Radioembolization'.

assistant: **Concept**

Current SPECT/CT scanners are not suitable for guiding interventional procedures involving the administration of radionuclides in a patient. These scanners are too large and not flexible enough to smoothly integrate into the intervention room. Hence, the radionuclide distributions obtained in these procedures can currently only be evaluated after the interventional procedure is finished, resulting in sub-optimal treatment outcomes. To address this problem, we have developed a SPECT/CT scanner optimized for use in the intervention room so that the monitoring of the radionuclides can instead be done ‘live’ during the procedure. For one specific interventional procedure in which radionuclides are injected, radioembolization for the treatment of liver cancer, our interventional scanner can: 1) improve tumor kill by real-time feedback on the tumor doses, 2) minimize adverse effects by early detection of unwanted targeting of healthy tissue, 3) improve patient comfort by shortening the procedure, and 4) as a result reduce the cost for society. Fundamental research for the development of the interventional scanner was performed in the previously granted ERC CoG. In this ERC Proof of Concept, we will investigate the commercialization of our device. This will be achieved by initiating three routes in parallel: 1) demonstrating the scanner performance in a promising interventional radionuclide therapy treatment (radioembolization), 2) determining our intellectual property rights position and strategy, and 3) performing a thorough market and competitor analysis with feedback from the market. These results will be combined to form a business strategy for commercialization with which to engage with commercial partners. These actions could result in the mass-production of the interve
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Isotopic links to atmopheric water's sources' under Horizon 2020.

assistant: **Concept**

The hydrological cycle, with its feedbacks related to water vapour and clouds, is the largest source of uncertainty in weather prediction and climate models. Particularly processes that occur on scales smaller than the model grid lead to errors, which can compensate one another, making them difficult to detect and correct for. Undetectable compensating errors critically limit the understanding of hydrological extremes, the response of the water cycle to a changing climate, and the interpretation of paleoclimate records. Stable water isotopes have a unique potential to serve as the needed constraints, as they provide measures of moisture origin and of the phase change history. We have recently spearheaded a revised view of the atmospheric water cycle, which highlights the importance of connections on a regional scale. This implies that in some areas, all relevant processes can be studied on a regional scale. The Nordic Seas are an ideal case of such a natural laboratory, with distinct evaporation events, shallow transport processes, and swift precipitation formation. Together with recent technological advances in isotope measurements and in-situ sample collection, this will allow us to acquire a new kind of observational data set that will follow the history of water vapour from source to sink. The high-resolution, high-precision isotope data will provide a combined view of established and novel natural isotopic source tracers and set new benchmarks for climate models. A unique palette of sophisticated model tools will allow us to decipher, synthesize and exploit these observations, and to identify compensating errors between water cycle processes in models. In ISLAS, my team and I will thus make unprecedented use of stable isotopes to provide the sought-after constraint
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Validation of photoacoustic, photothermal and related methods for detection of early spoilage, adulteration and quality assessment in food industry' (1994-1998).

assistant: **Concept**

Foreseen ResultsIt is foreseen that the use of (laser based) photoacoustic, photothermal and related techniques in the food industry will increase in the years to comeMany valuable contributions to the significant and a worldwide progress observed during recent years in the field of (laser) photoacoustic science, were made by the scientists from Europe. However, potential of newly emerged photoacoustic, photothermal and related techniques for application in the food industry has not been fully exploited so far. This was the main reason for several experienced groups originating from Mid, Eastern and Western Europe to bundle their know-how and excellent infrastructures, and by means of an ambitious, joint research project investigate the capabilities of above methods for : i) quality assessment of some selected foods (honey, milk and dairy products, oil, margarine) and beverages (fruit juice), and ii) the detection of adulteration and of early spoilage stage; both issues are of the great common interest. Some of the methods proposed here will be used to obtain presently lacking values of temperature dependent thermophysical parameters (thermal conductivity, volume specific heat and thermal diffusivity) for raw and finished food products within a wide range of temperatures including region of phase transitions.The project will include a collaborative effort of physicists, chemists, microbiologists and food scientists associated with five universities and four institutes. The industrial partners (one as a subcontractor) include two medium to large sized companies from Mid Europe producing fruit juices, marmalades and dairy products. Major national institute for food quality research is one of participants from Western Europe.Whenever possible, the results collected by thes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Developing Careers through Social Networks and Transversal Competencies'.

assistant: **Objectives**

A key challenge in improving life-long learning, employee flexibility, and skill-matching is the assessment of workplace relevant competencies and the planning of individual learning paths for career development. The aim of this project is to develop a personalised learning environment for career development. The environment will provide assessment of transversal competencies and social capital to highlight learning opportunities for career development. It will combine this with personalised visualisations of potential career paths to inform and guide learners towards realistic and attainable careers. DEVELOP will:- Use social network analysis to assess social capital that has been built among colleagues- Assess transversal competencies such as leadership and collaboration, using game-based assessment techniques combined with social network analysis evidence- Apply AI planning techniques to recommend learning opportunities for career development- Create interfaces for employees and HR to aid both career awareness and talent management within an organisation- Support internal mobility of employees and better skill-matching to increase employee engagement and reduce attrition rates- Consider diverse sources of social network evidence including enterprise social networks, email, and self-reporting tools- Gain end-user trust by providing clear informed consent and transparent data privacyDEVELOP will deliver an adaptive learning environment that dynamically tailors the exploration, comprehension, and planning of learning opportunities and career paths in medium and large companies. It will aid employee learning through reflection on transversal competencies and social capital, as key enablers of career development.  DEVELOP will use a close academic-industry collaboration t