RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Tracing Queer Citizenship over Time:  Ageing, ageism and age-related LGBTI+ politics in Europe' to be submitted under Horizon Europe.

assistant: **Abstract**

Sexual and gender diversity are constitutive elements of democratic societies which have been targeted by extreme-right populism and other anti-democratic forces. Taking queer citizenship as a set of criteria through which democracies can be evaluated, TRACE explores the extent to which the EU has influenced local political and socio-legal advancements in LGBTI+ rights, narratives and experiences over time. To respond to this aim, TRACE develops an innovative age-sensitive, analytical lens focused on ageing, ageism and age-related LGBTI+ politics through which progress and backlash in countries that experienced substantial changes in their intimate citizenship regimes will be investigated.TRACE uses a multiscale life-course approach centred on gendered/sexed processes of ageing in the context of a rapidly changing Europe. LGBTI+ elders carry a unique embodied knowledge of struggle and resistance, offering a precious lens through time, from once criminalized outlaws to the intimate citizens of today’s EU LGBTI-freedom zone, who outlasted a variety of challenges, including the AIDS pandemic and related stigma. The countries included in this research are Portugal, Italy, Greece, Malta and Slovenia, offering a comprehensive overview of changes across time and space in Europe, including the impacts of religion and secularism, traditional and advanced intimate regimes, and the relation to the EU LGBTI+ evolving framework. With a focus on the South as an imagined political space of silence and resistance, the research enables an in-depth portrait of different regions of Southern Europe today, grounded on the life stories of older adults whose lifespan accompanies these changes. Their shared and untold past of oppression will inform scholarly knowledge regarding current and fut
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Sensitive and differential blood and cerebrospinal fluid test for neurodegenerative dementia diagnosis' (NEUROSCREEN).

assistant: **Innovation**

The project aims to develop an integrated system allowing differential diagnosis of neurodegenerative diseases based on several patented, sensitive and robust technologies. This system uses an ultrasensitive detection of specific direct and indirect amyloid-related markers in the cerebrospinal fluid and in blood, with new derivative products of nano/micro biosciences. Among diseases with amyloid deposits, the NeuroScreen project will focus on Alzheimer and Prion diseases for which some ambiguities still exist regarding their differential diagnosis. At present, their diagnosis must be confirmed by post-mortem cerebral analysis. The experimental work is broken into 7 workpackages management being gathered in a WP0, with the corresponding objectives being achievable within the 36 months of the project: WP1 Design, optimisation and production of the early test; aim: neuroaptamer prototypes, neuro-strips, neuro-magnetic beads, validation of packaging and sterilization process, and stabilised and validated supports. WP2 Alzheimer Diagnostic: Tau-181 and -231 markers; aim: choice of the marker candidate and the prototype to be tested in a multiplex trial. WP3 Dementia diagnostic and Lewy bodies: -synuclein marker; aim: development and validation of a suitable assay for -synuclein oligomers. WP4 Creutzfeldt-Jakob: PRION; aim: validation of aptamers, neurostrips and i-PCR. WP5 Therapeutic follow-up; aim: biological markers for future therapeutic follow-up validation WP6 Integrative section and fundamental knowledge derived from the other WPs; aim: validation of the multiplex assays systems. WP7 Accompaniment and regulatory follow-up. The work will be carried out by a consortium made up of 12 partners, coming from 6 European member-states. A complementary expertise and a multidis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Smart ELECTrodeposited Alloys for environmentally sustainable applications: from advanced protective coatings to micro/nano-robotic platforms'.

assistant: **Objectives**

SELECTA is a highly inter-disciplinary initiative which has the primary goal of training young researchers in the field of smart electrodeposited metallic alloys suitable for environmental / sustainable development applications. The Network encompasses the fabrication and in-depth characterization of: (i) innovative protective coatings, (ii) resilient micro/nano-electromechanical systems, and (iii) wirelessly actuated micro/nano-robotic platforms for cutting-edge environmental applications. The project will explore new types of electrodeposited alloys (based on Fe, Cu or Al; free from hazardous and scarce raw elements), with tunable structure (amorphous, nanocrystalline), morphology (dense, nanoporous) and geometry (films, micropillars, nanowires), to meet specific technological demands (high wear/corrosion resistance, superior magnetic properties or hydrophobicity). SELECTA aims to integrate technological progress with environmental sustainability concerns, which is one of the major “Societal Challenges” listed in the Horizon 2020 Work Programme. Several disciplines (Physics, Electrochemistry, Engineering, Environmental Sciences, Biology and Robotics) converge together to provide a holistic approach to accomplish the SELECTA goals. The project brings together 10 Beneficiaries and 7 Partner Organizations (including 5 private companies), belonging to 10 EU Member States (plus Switzerland and Serbia). Special efforts will be devoted to bridge fundamental science with commercialisation of the research outcome. The complementarities among partners will render a high-level, multi-faceted educational programme. World-class research will be combined with unique training opportunities in soft skills, such as career planning, dissemination, intellectual property rights, entrepre
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'In-vivo microstructure of the cornea: implications for vision, health, and disease' in the context of a Seventh Framework call.

assistant: **Objectives**

The research proposal MICROCORNEA will bring knowledge and expertise concerning in-vivo microstructural analysis of the cornea from Canada to Sweden, to be applied in innovative clinical and basic science research projects. The objectives of this proposal are to utilize in-vivo microstructural analysis to evaluate the biointegration of novel materials implanted in patient eyes for the restoration of vision, to detect the recurrence of dystrophic changes in patients after excimer laser treatment, to describe the microstructural corneal features in Swedish families with new, hereditary corneal dystrophies, to develop a means to detect lymphangiogenesis non-invasively in a live cornea, and to non-invasively observe phenotypic changes in corneal stromal cells in real-time. These objectives will be achieved by first imaging the microstructural characteristics within live corneas by using in-vivo laser-scanning confocal microscopy, and subsequently quantifying, analyzing, observing, and interpreting the various anatomic features of the cornea at the microscopic level, and relating the findings to the specific research questions posed. Research results will be disseminated at conferences and scientific meetings and will result in the submission of a minimum of six articles to international, peer-reviewed scientific journals. The expertise of the Incoming Research Fellow will be additionally applied to train researchers from Sweden and the Scandinavian countries to perform in-vivo laser-scanning confocal microscopy and microstructural analysis of the cornea. Once completed, the innovative research outlined in this proposal will establish the Host Institution in Sweden as a premier facility for innovative corneal microscopy research in Europe and will promote long-term research
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'A data-driven computational framework to discover how behavior impacts processing in mouse visual cortex' (Vision2Action).

assistant: **Concept**

Our movements influence how we perceive the world. Our eyes are attached to a behaving body creating a complex dynamical stream of input that can provide additional information if we know the movement pattern. The interaction between motor and visual signals is especially pronounced in rodent visual cortex that exhibits a substantial, multi-dimensional contribution from motor signals, even in early visual areas. However, a fundamental principle that governs the interaction between visual and motor signals across neurons and visual areas is currently unknown, especially for freely moving animals. I hypothesize that the interaction between visual and motortuning in mouse visual cortex provide the animal with a consistent and behaviorally beneficial multi-modal picture of its environment. However, studying the interaction between motor behavior and sensory processing is challenging as experiments face a trade-off between experimental control in head-fixed animals (but limited movement) and the availability of rich movement signals in freely moving animals (but limited experimental control). I propose that this trade-off can be bridged by a data-driven in silico neuroscience approach that compiles experimental data into a digital twin that captures the interaction between physiology, motor behavior, internal state, and a model of the environment. The goal of this proposal is to build such an in silico framework to capture the detailed influence of motor behavior on visual processing in freely behaving mice. I will use this framework to discover fundamental organizational principles of the relation between visual and motor tuning across neurons and areas in mouse visual cortex, use them to test computational theories, and develop computational models to quantify their behavi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Symposium and workshops on cephalopod biomass and production' (CEPHSYMP), addressing dissemination and exploitation.

assistant: **Impact**

The proposal will facilitate an international symposium and four linked specialist workshops to address key issues relating the biomass of cephalopod populations to their productive capacity and that of the marine ecosystem. The outcomes will be relevant to the understanding of the marine environment and management of fisheries.Objectives:1. Organise and manage an international symposium on the theme Cephalopod Biomass and Production 5th-7th July 2000 and facilitate contributions from, and attendance at, the meeting of a fully international range of participants.2. Organise and manage a suite of specific specialist and technical workshops 3rd--4th July 2000, in support of the symposium topic.3. Showcase the relevant work of European partnerships in the FAR, AIR and FAIR programmes.4. Provide special opportunity to draw in the contributions from the ex-Soviet Union countries.5. Manage and edit a scientific volume to disseminate the proceedings of the meeting.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Dynamic buckling of fiber composite shells' to be submitted under Fourth Framework.

assistant: **Abstract**

Research objectives and content The objectives are to find out the suitability of finite element codes widely used in European industry to deal with dynamic buckling behaviour of light-weight, impulsively loaded fiber composite shells, and to learn about this problem. Dynamic buckling is critical for safe operation, e.g. with landing of aircrafts, starting of launchers, and crash of land and water vehicles. Codes considered will be MSC/NASTRAN, MSC/DYTRAN, ABAQUS, DYNA3D, and PAMCRASH. Computations for cylindrical shells will be performed and evaluated with respect to - suitability of the codes considered, - modelling and solution methods, - influence of laminate set-up, - identification of unsafe operation due to critical interaction of loading and buckling dynamics. Experiments will be performed, and the results will be compared with numerical predictions. Training content (objective, benefit and expected impact) The training contributes to my ability to deal with safe design of future light-weight structures. It is part of my specialisation to non-linear, time-dependent problems. I will learn how to computationally handle dynamic buckling problems of fiber composite shells, and profit from DLR's capacities concerning dynamic buckling tests. Dealing with DLR's MSC codes increases my basic experience with finite element systems. Links with industry / industrial relevance (22) The hosting group has ongoing collaboration with European industry concerning design guidelines against buckling of fiber composite shell structures.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Albumin particles for intra-articular delivery of celecoxib to treat osteoarthritic inflammation.'.

assistant: **Concept**

Osteoarthritis (OA) is the most common chronic condition of the joints and is predicted to become the fourth largest cause of disability in the world by 2020. Its complete mechanism is yet to be deciphered. Though it is not curable, several medications are prescribed to manage the symptomatic OA, of which the oral and topical medications have shortcomings and the better option is the intra-articular (IA) delivery of free corticosteroids and hyaluronic acid. However, IA delivery is challenging due to the rapid clearance of the free injected molecules from the joint space and outcomes are suboptimal in terms of efficacy and a need for repeated injections. Our objective therefore is to load a candidate drug in a long-acting delivery system and inject it directly into the inflamed knee of a rat model of OA, following in vitro bioassay screening in primary human synoviocytes. Thus, in this project, we propose to develop non-toxic, biocompatible and biodegradable albumin particles loaded with the non-steroidal anti-inflammatory cyclooxygenase-2 inhibitor, celecoxib. This method is expected to reduce the side-effects associated with oral administration of celecoxib. In addition, it will also increase the drug local concentration in the joint and the controlled release of the drug will lead to reduction of inflammatory biomarkers in joints. The project is in line with the EU’s Horizon 2020 Programme focus area - Health, Demographic Change and Wellbeing and UN Sustainable Development goal - Good Health and Well-Being. It will be carried out by the researcher and supervisors who are experts in DDSs development, OA therapy and translational pharmaceutics. Both the researcher and the host are expected to benefit in this collaboration and the researcher will gain experience that wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Laser-Assisted Surgical System to Revolutionize Cardiac Bypass Surgeries'.

assistant: **Innovation**

Coronary Artery Bypass (CAB) surgery is performed annually in >700,000 patients to treat coronary artery disease andprevent myocardial infarction (heart attack). Standard CAB surgery involves a highly invasive open-heart procedure inarrested/non-beating heart, that is associated with long recovery times and severe complications. The surgeons are seekingfor less invasive, closed chest CAB procedures on beating heart, but current solutions are technically extremely challenging and therebyonly used in <1-3% of all surgeries. The vision of the SAFE-CAB consortium is to make the minimally invasive CABsurgeries available to all surgeons as a novel standard of care, thereby substantially improve patient outcomes and reducehealth care costs. The goal of the project is to bring to market a first-of-its-kind laser-assisted minimally invasive surgicalsystem (surgical kit containing surgical implant and laser catheter). SAFE-CAB enables minimally invasive procedure onbeating heart, without the need for arresting blood flow or complex hand suturing. With shorter recovery times, lesscomplications and improved survival rates in high-risk patients, the SAFE-CAB technology has a potential to replace high-riskopen-heart surgeries. Replacing only 15% of open-heart surgeries in Europe and US translates to annualmarket opportunity of >€89M and >€192M. Dutch SME AMT Medical has developed the proprietary SAFE-CABtechnology to clinical readiness. To substantially accelerate the market entry of the product, the company partners with a leading European cardiac surgery hospital Deutsches Herzzentrum Berlin and a pan-European clinical/regulatory medical device company HEMEX toobtain regulatory approval through final clinical validation . To realize European wide-implementation, the consortium is c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Raising Innovation Capacity for Innovative Companies from Latvia (2020-2021)' to be submitted under Horizon 2020.

assistant: **Abstract**

The overall objective of the project is to contribute to smart growth in the European Union by increasing the efficiency and effectiveness of investments in research, development and innovation and by contributing to a better and more efficient connection of actors along the innovation chain. To achieve this objective the following measures are foreseen:• To support SMEs, as the beneficiaries of the SME support instrument to identify bottlenecks to the creation of economic impact in companies benefiting from grants by Horizon 2020 Enhanced European Innovation Council (EIC) pilot and address these bottlenecks with the help of capable coaches;• To increase the efficiency and effectiveness of innovation processes in small and medium sized enterprises with significant innovation activities that could potentially become beneficiaries of European support to research and innovation but would not have effective access to consulting services for innovation management.In practice at least fourteen (14) specialised on average 7-day service packages will be delivered to SMEs to assist them in successful benefiting from Horizon 2020 Enhanced European Innovation Council (EIC) pilot and increase their innovation management capacity beyond this programme.The services addressed by the current proposal will be integrated in already existing Enterprise Europe Network services.


**Keywords:** SME instrument, key account manager, innovation management capacity, EIC pilot
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Binuclear Non-Coupled Copper Enzymes in Neurobiology: An Integrated Computational/Spectroscopic Investigation'.

assistant: **Objectives**

Every third protein contains metal as cofactor. Cu-enzymes plays crucial rules in key processes in bioenergetics, mitochondrial respiration, neurotransmitter biosynthesis, antioxidation and pigmentation Therefore they are intensive targets for discovering new drugs and the understanding of their structure-functions relationships will provide new insight in translational and biomedical research.In this  Marie Curie  International Outgoing  Fellowship  I will investigate the mechanism  of  important two bi nuclear cupper enzyme – Peptidylglycine α-Amidating Monooxygenase (PAM) and  Dopamine β-Monooxygense (DBM) which catalyze  hydroxylation of substrates in crucial importance for neurobiology . The miss functionalities of these enzymes are related with nervous system disorders therefore revealing it mechanism will provide advanced opportunities for design of new drugs. In order to achieve this knowledge we will apply integrated combination of the most advanced spectroscopic techniques and state of the art computational methods.""