RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Interaction between environment and fisheries - a challenge to management' to be submitted under Sixth Framework.

assistant: **Abstract**

The IBEFish has two objectives: 1) to share the results and theoretical understandings gained in past projects with regard to the ecosystem approach in fisheries management with a special focus on the role of participation in integrated management of the interaction between environment and fisheries; and 2) to make practical recommendations for improving fisheries management towards an ecosystem-based approach especially emphasising the need for an enhanced knowledge-base, legitimacy and trust-building in the management. The main objectives will be reached by two tasks. First, by synthesising the results of projects on interaction between environment and fisheries from a perspective of effective participation in integrated management. Some of our case studies explore lessons learned in integrated management of other natural resources, which will result in improved understanding of the ecosystem management. The synthesis uses a framework for evaluating effectiveness of participatory decision making. Second, to disseminate the findings to decision-makers, the industry, environmentalists, regulators and the scientific community. The IBEFish will organise a workshop to convene researchers working on similar questions all over Europe. In addition, we will disseminate our findings to decision-makers and stakeholders by producing policy briefs and to a larger audience in professional press. Finally, the project will outline new research questions to support effective management of the interaction between environment and fisheries. The IBEFish project support progressive implementation of the ecosystem-based approach to fisheries management", a policy-relevant objective that was highlighted in the research priority 1.3. of the call. The project will both explore the conceptual
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Controlled cryo-EM sample preparation through DNA-Origami pillars' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Electron cryomicroscopy (cryo-EM) is rapidly emerging as a powerful technique for high-resolution structure determination of protein complexes. Despite recent advances, there is still ample room for improvement of this method, in particular regarding sample preparation. Outstanding challenges are reproducibility of freezing conditions to obtain an optimal ice thickness; to prevent unfolding or preferential orientation of proteins against the hydrophobic air-water interface; and a limited accuracy of beam-induced motion correction for relatively small particles. Here, we propose to study how DNA origami objects that are added in with the sample may affect cryo-EM grid preparation. In addition, by examining a variety of DNA origami structures in the electron microscope, we also aim to identify and improve on structural weaknesses in their design. We will test new design strategies, analyse those, and use them for application in cryo-EM. Thereby, this proposal will facilitate both cryo-EM structure determination and the design of nano-tools that are made from DNA.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Support to Precursor SSA Services' to be submitted under Seventh Framework.

assistant: **Abstract**

The European Union Satellite Centre (EUSC) is proposing its expertise in handling, analysing and disseminating data and derived products within the highest security standards and mission critical cycles to contribute through the SPA (Support to Precursor SSA services) study to the technical definition of Space Situational Awareness (SSA) services and to participate to the validation of critical precursor SSA services:•Satellite conjunction warning;•Satellite over-flight alerts;•and Space debris re-entry prediction.In order to perform the SPA study, the EUSC proposes to host at a class II security area within its already existing premises a copy of a SSA system to be developed by the European Space Agency (ESA). The EUSC could be tested as a hub to exchange secure information with SSAs’ stakeholders, testing possible technical implementation models of the governance / data policy to be developed by the European Union (EU) and ESA.The final output of the SPA supporting action will be a study report summarising the gained knowledge, including lessons learned, on SSA during the execution of the SPA study and recommendations in view of further development of SSA in Europe, particularly on the technical aspects of its Governance and Data Policy.SSA refers to the knowledge of location and function of space objects and space environment, including operational satellite, space debris, near earth objects and space weather. The development of a European system will underpin the exploitation of space assets, a key capability contributing to autonomous access to space for the EU (as requested by the European Space Policy, drawing on existing capabilities and infrastructures at national as well as European level).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Aspects of G2 Geometry' in the context of a Seventh Framework call.

assistant: **Objectives**

A first objective of this proposal is to construct large numbers of new G2 manifolds by extending Kovalev's ``connect sum"" construction to a larger class of 3-folds. This will be achieved via a combination of differential, algebraic and analytic methods which will lead to a very good understanding of the topology of these manifolds, of the relationship to the geometry of the generating 3-folds, and of the limits of the ``connect sum"" construction.A second objective is to construct new examples of associative submanifolds, partly using the above results, and to study moduli spaces of associative submanifolds with respect to various notions of ``tame"" G2 structures.A third objective is to construct holomorphic 3-folds with trivial canonical class starting from integral affine manifolds.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Role of calcium in the regulation of cell polarity in neurospora' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

The primary objectives of the proposed project will be to analyse the role of cytosolic free calcium ([Ca2+]c) in Neurospora crassa for regulating: 1. The initiation of cell polarity (during hyphal branch formation). 2. The maintenance of cell polarity (during hyphal tip growth). 3. The reorientation of cell polarity (during hyphal tip growth in an applied electrical field). Imaging, quantitation and experimental manipulation of Ca2+ dynamics in living hyphae will be central to the project. The research will involve using: 1. Pressure microinjection of Ca2+-sensitive dyes and caged probes. 2. Confocal imaging of Ca2+-sensitive dyes. 3. Ratio imaging of ([Ca2+]c). 4. Experimental manipulation of Ca2+signalling using photoactiveatable caged probes. 5. Analysis of polarity mutants impaired in chitin synthase and protein kinase activities.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for '‘Key account management’ for the SME Instrument, FTI and FET-Open beneficiaries and ‘Enhancing SME innovation management capacity’ as proinnovative services for SMEs in the regions of Southern Poland' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The general objective of the project is to contribute to smart growth of Southern regions of Poland by increasing the efficiency and effectiveness of investments in innovation and by contributing to more efficient connection of links along the innovation chain and by this – to contribute to the smart EU growth. The specific objectives of the project are: (1) efficient management of the relation between SME (beneficiary of the SME Instrument, Fast Track to Innovation and Future and Emerging Technologies Open) and the coach in purpose to increase the number of projects financed within Horizon 2020 programme completed with a successful commercialization and (2) development of regional SME innovation management capacity: by carrying out innovation management gap analysis, development of the tailored action plan for increasing the effectiveness and efficiency of their innovation management system and implementation of the targeted actions to address bottlenecks and weak points between the innovation capabilities and innovation goals. The objectives will be achieved by performing two kinds of service packs: Key Account Manager and Enhancing SME innovation management capacity, based on the common for the whole Enterprise Europe Network standard, compliant with European Innovation Management standards - CEN/TS 16555:1. The project is relevant to the Work Programme in Horizon 2020 and helps to overcome lack of capacity in innovation management, recognised as an important barrier in creating economic impact on innovation activities in SMEs. The project is addressed to the specific challenge and scope of the topic and offers mentoring and coaching services to beneficiaries who need this help. The project will make SMEs high quality innovation support services available where these
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Innovation studio and exemplary developments for product service engineering' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

The main problem is that service engineering is not a traditional part of engineering education and there is a gap in postgraduate qualification courses and also in the further education and training in companies. Only bigger organisations have the resources to introduce a systematic development process for service innovations. This worldwide experience especially from bigger companies should be made available and made suitable for the needs of SMEs. The whole project is split into the following three subproblems: General concepts (corresponding TRA 1.5 improved development process of innovative service concepts), Innovation studio for product-services, feasibility studies for PSS as exemplary R&D for innovative product-services.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Coordinating Noise Transportation Research and engineering solutions' in the context of a Sixth Framework call.

assistant: **Objectives**

Within the next few decades the European vehicle industry will face a formidable task with respect to noise pollution in urban areas. In the past the noise and vibration research effort in vehicles have been considerable. Despite this no real breakthrough regarding new solutions of noise reduction can be claimed. Sustainable development in vehicle engineering, i.e. to save natural resources with respect to material and energy, requires lightweight, low drag design, etc. However, a strict lightweight design contradicts requirements such as low noise, safety and functionality. The main reasons for such poor results are in fragmentation of European research and the lack of lasting cooperation between universities and industries. This negative trend must be broken. The overall aim of CANTOR is to engage experts from vehicle manufacturing industry chain from system to component level, government agencies and renowned research groups, jointly focussing on improved performance; with a reduced impact on the environment, enabling a balanced system cost and maintaining comfort in road, rail and waterborne vehicles. The means to achieve the goals are the accumulation and technology transfer of existing knowledge and information on new prediction tools, measurement techniques, research plans, material data as well as new educational programmes applied to vehicle acoustics. The aim is also the formulation of new joint research programmes between industry and universities. The mobility of personnel within the Consortium would automatically be stimulated by the partnership enabling inter-research institute fast track exchange and highly-relevant cross fertilization effects.  The results will be disseminated at seminars, meetings and workshops. The project, which has a research and edu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Smart Cities EMC Network for Training' (SCENT) under Horizon 2020.

assistant: **Objectives**

The global vision of Smart and Sustainable Cities is greatly restricted by the rapid increase of interference and interoperability problems which occur through the interaction of electrical power with information technology and communications equipment. This interconnected systems-of-systems infrastructure creates a complex electromagnetic environment in which interoperability of the electronic systems has to be achieved. There is an urgent need to conduct greater understanding in Power Quality (PQ) and (conducted) Electromagnetic Compatibility (EMC) due to the changing dynamics of the field. The main issue is the insufficient number of qualified engineers for the latest developments in smart cities, renewable generation and electric vehicles. A highly trained cadre of engineers (a new breed) is required to lead this area. To date no specific doctoral programme in this field is available in Europe resulting in well trained researchers and engineers being scarce.SCENT will create a network to train highly skilled engineers through an integrated doctoral training program based on the essential research required in PQ and EMC that can underpin all future technological developments, strongly linked to industry, and bridging the gap between research and industry for translation of new knowledge. Designed into the project are specific innovations with methodologies to optimize the design of power distribution networks inside buildings and industrial plants, as well as transport systems, with respect to compatibility (no interference) and efficiency in the distribution networks and connected electronic systems. The partners of the network consist of leaders in these fields and relevant industrial stakeholders resulting in a unique and effective network in Europe and globally.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Multifunctional Conducting Polymer Devices for Electroresponsive Cell Regeneration' in the context of a Seventh Framework call.

assistant: **Objectives**

Disorders of electrically responsive tissues including spinal cord injuries, neuromuscular, neurodegenerative, and cardiac diseases,  are chronic and progressive in nature leading to high disability with considerable social impact and economic consequences. The need for therapies that could facilitate regeneration of electroresponsive cells has become a high priority in medical research. Although tissue-engineered constructs are being designed to assist the growth and differentiation of these cells, they are largely limited by their inability to simultaneously provide more than one stimuli vital for cell regeneration. Thus, there is an unmet need to develop a multifunctional construct that could provide more than one stimuli concurrently or sequentially. Conducting polymers (CPs) are emerging as a new class of bioactive materials to interface with these cells due to their unique ability to conduct electricity. This proposal will take an innovative approach to develop multifunctional polythiophene CP constructs that will provide a substrate for cell attachment, controlled delivery of biomolecules and direct electric stimulation to enhance cell regeneration. In stage one of the proposal, novel polythiophene scaffolds with appropriate architectural structures will be developped and optimised in terms of their electric properties and capability to promote cell adhesion and growth. In the second stage, selected biomolecules will be loaded within these scaffolds and their “on demand” release will be investigated. Finally, CP structures with optimised properties will be assessed for direct electric stimulation to enable cell proliferation and differentiation. These novel CP scaffolds will be reported for the first time by a European research group aiding towards the competitiv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Understanding the role of CyclinB1-NuMA interaction in spindle orientation and epithelial morphogenesis' in the context of a Horizon 2020 call.

assistant: **Objectives**

In multicellular organisms, oriented cell divisions sustain tissue morphogenesis, tissue architecture and homeostasis by ensuring the correct positioning of daughter cell after mitosis. Accurate execution of oriented divisions and chromosome segregation relies on the positioning of an essential actor, the mitotic spindle. The consequence of spindle misorientation is drastic. Disruption of any of the spindle orientation factors could lead to genetic instability, tissue disorganization and tumorigenesis. However, cell division is controlled not only in orientation, but also in time. Indeed, spindle orientation is also very important for a wide range of developmental processes, ranging from germline stem cell division to epithelial tissue homeostasis and regeneration. A more complete understanding of how spindles are oriented will therefore require more extensive research, e.g. using CRISPR-based strategies to interrogate the proposed interactions in vivo, into how the spindle-orienting machinery is localized and regulated in multiple systems. The aim of this project is to advance knowledge on how cell cycle regulates spindle positioning and its contribution in epithelial morphogenesis in the intestinal tissues. This advance knowledge will serve to better understand the pathogenic mechanisms of important human diseases such as cancer.


**Keywords:** NuMA, CyclinB1, Spindle orientation, Epithelial morphogenesis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Organization and learning-associated dynamics of prefrontal synaptic connectivity' to be submitted under Horizon 2020.

assistant: **Abstract**

How does experience alter the functional architecture of synaptic connections in neural circuits? This question is particularly pertinent for the complex circuits of the medial prefrontal cortex (mPFC), a high-order associative neocortical area that plays a crucial role in flexible, goal-directed behavior. The mPFC is densely interconnected with cortical and subcortical circuits, and its neurons were shown to undergo substantial experience-dependent structural remodeling that is thought to support learning and memory consolidation. However, little is known regarding the synaptic organization of this complex circuit, and of the functional implications of its experience-dependent structural remodeling. In this proposal, we aim to uncover the organization and learning-associated dynamics of functional connectivity in the mouse mPFC.To obtain high-resolution maps of cell type-specific synaptic connectivity in the mPFC, we will combine single-cell optogenetic manipulation with calcium imaging and electrophysiology in vitro, and establish the circuit-wide organization of connectivity within and between defined projecting neuron populations. We will test the hypothesis that pyramidal neurons projecting to subcortical targets form tightly interconnected subnetworks, and that inhibitory inputs to these networks, through selective innervation, can modulate information output from the mPFC.To understand how learning changes the functional synaptic organization of the mPFC, we will establish an all-optical system for interrogation of synaptic connectivity in vivo. We will utilize this powerful platform to test the hypothesis that prefrontal-dependent learning is associated with reorganization of local-circuit functional connectivity among identified subcortically-projecting cell as