RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Metal Transport in the Environment' in the context of a Seventh Framework call.

assistant: **Objectives**

Understanding the processes that control the transport of metals in the environment is essential for a wide range of fields, including environmental protection and remediation, mineral resources, climate change. Through recent analytical developments, it is possible, using natural variations in metal isotopes, to identify and quantify how metal concentrations in natural waters are controlled by interactions with mineral surfaces, microbially-mediated reactions, and release during mineral weathering, and so significantly advancing our understanding of the fate and consequences of metal transport in the environment However, such applications have not been extensively exploited. The proposed MetTrans scientific and training Network will address a range of critical societal and industrial applications. This includes the abiotic and microbial immobilization of contaminants, the role of metals in carbon sequestration, and the response of metal transport to climate change. This requires interdisciplinary input, from chemistry, geology, physics, biology, hydrology, and engineering, and the solution to many of these problems requires close academic-industrial collaboration – academia will provide the scientific expertise and state-of-the-art analytical techniques to the practical applications confronted by industry. Although the particular research questions considered are diverse, the underlying scientific principles and analytical techniques are similar. This therefore provides an excellent platform to train young scientists in using of isotopic methods, understanding metal behaviour, and utilizing skills broadly. The Network focuses on providing training on analytical skills, on understanding fundamental principles, and on modelling, and exposes young scientists to a wide ran
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Atrial Fibrillation - Implications of Basic Research and Novel Curative Approaches Interventional therapy of atrial tachyarrhythmias'.

assistant: **Objectives**

Atrial fibrillation is the most common persistent arrhythmia in man. Although atrial fibrillation has a major impact on morbidity and mortality, current treatment focuses on the prevention of embolic events by the use of anticoagulation. Rhythm stabilizing therapy is of modest success. In the last couple of years major progress has been made in the understanding of the pathophysiology of atrial fibrillation.Catheter ablation, nowadays the preferred treatment for paroxysmal supraventricular tachycardia, has just recently been introduced as a potentially curative therapy for atrial fibrillation. However, many fundamental questions of the pathophysiology of atrial fibrillation and its treatment by catheter ablation, such as the effect of the underlying cardiac disease on the remodelling process or the necessity of anticoagulation after successful catheter ablation, are unsolved.The three main objectives of the planned conference are:- Provide a forum for high quality lectures for young investigators given by the leading experts in the field;- Allow young investigators from Europe to present their latest research to an expert committee;- Discussion between the scientific expert and the young investigator.Young investigators will give more than 50% of the oral presentations and will play a major role in the conference. A supplement volume of the European Heart Journal will be edited to support the dissemination of the information provided at the conference.The Euro conference will be followed by a EuroLab course focussing on catheter ablation of atrial tachyarrhythmias with a special emphasis on atrial fibrillation. Because of the- high incidence of atrial fibrillation in the general population, it is- mandatory to spread knowledge on the- most recent advances how to treat t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Social CHallenges and Innovation Platform' (SCHIP).

assistant: **Innovation**

Social Challenge Innovation Platform, SCHIP, aims at creating an online ecosystem to match pressing social challenges with innovative solutions, by supporting the co-development and execution by social innovators and SMEs of sustainable and market-oriented innovations with clear social impact. The action will enable European stakeholders to clearly define pressing social challenges; to promote a broad participation of social innovators, entrepreneurs and SMEs; to facilitate the testing of concrete solutions to prioritised challenges and their international scaling. SCHIP will provide a complementary grant-making mechanism, focused on the translation of challenges into practical and marketable solutions.The action will test a novel approach in the selection of solutions that is demand driven and user-centred. It will promote the ignition of these solutions by facilitating access to mentors, first clients and investors, and by building on the proven experience of the consortium networks in scaling social innovation across Europe.To maximise value for money and impact, SCHIP will leverage the know-how and reach out of the 3 partners: META Group with its long experience in managing financial instruments and meeting entrepreneurial needs; Impact Hub, the leading global network of centres for social innovation and social entrepreneurship with 85 Hubs, over 13,000 members and a proven track-record in managing social innovation challenge prizes; and EBN (The European Business and Innovation Centre Network), with its over 240 members, reaching out to more than 18,700 SMEs, 8750 start-ups and 485 large companies - 12% of them involved in social innovation related projects.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'A multicenter phase IIb study using HLA-unmatched allogeneic placenta-derived stromal cells (PLX-PAD) for the treatment of severe critical limb ischemia accompanied by mechanistic studies' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

PACE aims to transform the treatment of patients suffering from critical limb ischemia (CLI), a disease with high medical need, because of limited treatment options and poor outcome by applying a novel, off-the-shelf allogeneic placenta-derived stromal cell product (PLX-PAD). Despite improvements in medical care and revascularization, patients with CLI continue to have a high risk of major amputation (below the knee or higher) and cardiovascular death (1-year amputation-free survival <60%; 10-year mortality 70%). CLI has a strong social impact and its incidence is rising worldwide, including in Europe. The prevalence of CLI in the population aged 60–90 years is estimated as 1% (0.5–1.2%) with male to female ratio around 3:1. We will evaluate the efficacy, tolerability and safety of multiple intramuscular injections of HLA-unmatched allogeneic PLX-PAD for the treatment of CLI patients who are unsuitable for revascularization, in a randomized, double-blind, multicentre, placebo-controlled, parallel group phase II study. The European Medicine Agency (EMA) accepted PLX-PAD as pilot project for the new “Adaptive Pathways to Patients” to force timely access for patients to the new therapeutic option. The PACE consortium will go beyond the traditional clinical trial endpoints of safety and efficacy, by state-of-the-art characterizing molecular and functional signature of the PLX-PAD product(s), in depth investigating mechanisms-of-action of PLX-PAD therapy, and exploring biomarkers for understanding response/non-response in particular patients (stratification and therapy response markers). PACE partners are world-leading experts in scalable, clinical grade 3D-cell manufacturing approved by authorities, preclinical and clinical cell therapy, and biomarker analyses with well rec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Key Account Management process for beneficiaries of the EU funded programmes SME-instrument, FTI and FET-Open and services to enhance the INnOvation management capacities of SMEs' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The project aims at boosting the participation of European SMEs in the largest research and innovation funding programme of the EU, HORIZON 2020, especially in the SME instrument, in FTI or FET open and as a second to enhance the innovation management capacities of high innovative SMEs.Implementation activities are organized in two work packages (WP):Within the WP1 Key Account Management (KAM), the project will accompany beneficiaries of the SME instrument, FTI or FET in the implementation of their project ideas and initiate a coaching for them.In WP 2 Enhancing Innovation Management Capacity process (EIMC), the project activities should result in significant higher innovation management capacities of SMEs (). Therefore, the innovation capacities and processes, innovation strategies and internal organizations of SMEs as well as their relations with innovation partners will have to be assessed. For this, the partners will apply proven assessment tools. Identified gaps and bottlenecks in the innovation management capacities will be discussed and measures and action plans to overcome them will be defined by the EEN consultants jointly with the SME.KAMINO contains an assistance package for successful applicants in the SME instrument of H2020 and delivers assessments, advice and consultations to support SME to strengthen their innovation management capacities. Three EEN partners –ATI Kueste GmbH, Steinbeis-Forschungszentrum Technologiemanagement-Nordost and Technologiepark Warnemünde GmbH – work on the mentioned activities. The IHK zu Rostock– will formally act as coordinator for this action but will not implement any tasks.Best suited enterprises will be acquired by various sources, provided by the project partners. For the KAM-process the potential candidates will be nomin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Development of a scanning atom probe for nanoscale characterisation of thin-film materials, devices and coatings' (1994-1998) under Fourth Framework.

assistant: **Objectives**

Objectives and content New industrial materials increasingly depend for their properties on microstructure and phase chemistry at the nanometre scale. High-resolution microscopy and microanalysis is crucial for understanding the properties of nanoengineered materials and optimising their applications for new and improved products. In multilayered film (MLF) materials for example, which are used in hard-disk read heads, the magnetic properties are known to be dependent on the nano-scale chemistry of the interface. Microanalysis on this scale is needed to correlate the materials processing with the observed properties. The objective of this project is to build a new instrument, called the scanning atom probe, which will be capable of producing 3-dimensional images with atomic-scale resolution showing the chemical variations within thin-film materials and coatings. Previously the technique of atom probe analysis has had only limited application in thin-film materials due to the problems of producing specimens in the correct form for analysis. In the scanning atom probe, specimens can be made within thin films on flat substrates. This new instrument will provide an important tool in the development of nanostructured materials, underpinning the growth of nanotechnology in Europe for the 21st century. During the project, a scanning atom probe will be built which will allow the distribution of >80% of the atoms within a volume 20nm x 20nm x 20nm to be visualised, in 3-dimensions and with sub-nanometre resolution. An innovative counter-electrode design will be used in this instrument to give a mass resolution of m/Dm>300, allowing identification of single atoms, even in materials with elements close together in the mass spectrum. Specimens for the new instrument will be in the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Tailored measures supporting energy vulnerable households' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Between 50 and 125 million people are at risk of energy poverty in the EU. Efforts to address this issue will require a suite of measures informed by participatory and inclusive approaches. EnergyMEASURES will work to address energy poverty in seven European countries (BE, BG, IE, MK, NL, PL, UK) through two complementary and synergistic strands of work. Namely, through direct household engagements that are complemented and informed by cutting edge policy and practice innovations. The first strand will involve working with energy poor households to improve their energy efficiency through a combination of low-cost measures, and changes in their energy-related behaviours and practices. EnergyMEASURES will map out key indicators characterising those most at-risk of energy poverty, and will leverage partners’ ongoing projects and use their existing relationships with energy poor and at-risk households to recruit them for the household energy engagement programmes. Recruited householders will be provided with low-cost energy measures and empowered to change their energy-related behaviours and practices through an approach that is cognisant of existing housing conditions and is reflective of the lived experience of householders. The second strand will comprise working with municipalities, energy authorities, housing associations and other relevant actors to assess how current multi-level institutional contexts affect efforts to alleviate energy vulnerability in the participating countries. These interlinked activities will also consider gender differentials in both people’s relationship with institutional actors and their lived experience of energy, and EnergyMEASURES will work to mainstream this approach across the wider energy poverty community. Through this work the projec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Population interconnectivity and technological trajectories in southern Africa during the MIS3 through replicable lithic analysis' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Our species emerged from gene flow between structured populations across various regions of Africa. This process entailed intermitted events of coalescence and fragmentation, visible in late Pleistocene archaeological records through changing patterns of lithic technological similarity. In this framework, the MIS3 (59–28 ka) is a particularly intriguing period because archaeologists working in southern Africa have hypothesized that the marked regional variance in lithic technology is ascribable to cultural fragmentation and reduced information exchange among dispersed populations. However, it may also stem from the lack of a replicable system for recording and statistically analyzing lithic traits. The RStone project seeks to address this research challenge by pursuing three primary objectives. Firstly, it will develop a standardized method for recording lithic traits through comprehensive replicability experiments. Secondly, it will utilize this established recording system to collect novel lithic data from seven well-dated MIS3 stratigraphic sequences across Malawi, Mozambique, Namibia, and South Africa. Finally, it will conduct a quantitative inter-site comparison to explore techno-typological similarities and differences and determine whether the observed variance follows a pattern of isolation by distance or if other factors, such as geological constraints, played a role in shaping the way in which human foragers produced stone tools. This research will yield valuable open-source tools implemented in the R programming language and high-resolution datasets. In line with open science practices, RStone will prioritize the transfer and sharing of these resources, with a particular focus on engaging young African researchers. The extensive collaboration network will ens
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Audiovisual to Articulatory Speech Inversion' (ASPI).

assistant: **Concept**

Audiovisual-to-articulatory inversion consists in recovering the vocal tract shape (from vocal folds to lips) dynamics from the acoustical speech signal, supplemented by image analysis of speaker's face. Being able to recover this information automatically would be a major break-through in speech research and technology, as a vocal tract representation of a speech signal would be both beneficial from a theoretical point of view and practically useful in many speech processing applications (language learnin, automatic speech processing, speech coding, speech therapy, film industry...). The design of audiovisual-to-articulatory inversion involves two kinds of interdependent task. The first is the development of inversion methods that successfully answer the main acknowledged difficulties (non-unicity of inverse solution, lack of phonetic relevancy of inverse solutions, impossibility of using standard spectral data), and the second is the construction of an articulatory database that comprises dynamic images of the vocal tract together with the speech signal uttered, and that for several male and female speakers. For the inversion itself the main objectives are: 1.Development of inversion methods, 2.Investigation of additional constraints to reduce the under-determination of the inversion, 3.Evaluation of the inversion methods on articulatory data.  For the construction of the articulatory database: 4.Design and acquisition of articulatory data that enables both the development of articulatory models and the assessment of inversion methods, 5.Design of a low cost acquisition technology based on ultrasound and facial motion capture,  6.Exploitation of existing databases (mainly X-ray images previously acquired).  The consortium provides an outstanding blend of competences,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Tsetse flies and the control of African sleeping sickness' (TFCASS), addressing dissemination and exploitation.

assistant: **Impact**

African sleeping sickness is endemic in 37 sub-Saharan African countries covering 9M km2 with 60 million of the 400 million inhabitants at risk of the disease. Africa is in the middle of a HAT epidemic and WHO estimate that in 2004 there were 500,000 cases with 48,000 deaths and an impact of 1.53M DALYs (disability adjusted life years).In 2000 the African Union recognised trypanosomiasis as one of Africa s greatest constraints to socio-economic development. The trypanosomes causing the disease are transmitted by tsetse flies and currently the best means of area wide control of the disease is through vector control. To improve our current capacity to control African trypanosomiasis the African Union has established PATTEC. The African Union-PATTEC plan is to disrupt trypanosomiasis transmission through staged eradication of isolated populations of tsetse fly vectors on an area wide basis and by targeting isolated fly populations ensuring that fly eradication in an area is self-sustaining once achieved.W.H.O. / TDR has highlighted research goals which are key to the success of this approach and the two major ones are the research objectives of this proposal. First, area wide eradication of vector insects can be achieved in an environmentally acceptable way by the use of targets and traps. We wish to dramatically improve the efficiency of this process by developing novel attractants for use with traps/targets designed for use against palpalis group flies, which currently are the major vectors of human disease.Secondly, area wide control of the flies depends heavily on understanding the structures and mobility of the vector populations. Our current techniques cannot resolve these issues and we will develop new technologies for this purpose. We have assembled a unique group