RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Advanced Fast-Ion Loss Measurements at the JT-60SA and ITER tokamaks'.

assistant: **Objectives**

One of the main challenges towards the commercialization of fusion energy is the appropriate confinement of alpha particles in burning plasmas as well as fast ions generated by auxiliary heating systems. This project contributes to that objective by aiming at the temporal and velocity-space characterization of fast-ion losses in the most advanced tokamak experiments (ITER and JT-60SA).i) Commissioning of a Fast-Ion Loss Detector (FILD) and its installation at the JT-60SA tokamak, including the synthesis of its scintillator plate, testing of its reciprocating system, optical calibration and assessment of its structural integrity.ii) Assessing the escaping fast ions generated by the 500keV N-NBI at JT-60SA. These unprecedented time-resolved velocity-space measurements under different regimes of operation will be validated using Hamiltonian full-orbit simulations. Moreover, advanced, first-principle hybrid kinetic-MHD modeling with the MEGA code will be used to reproduce the losses induced by Alfvenic instabilities.iii) Designing the ITER FILD and developing the technical solutions required to survive the harsh conditions at the ITER first wall.  This includes thermo-mechanical assessment of the probe head, a synthetic diagnostic to estimate the signals, and the development of a scintillator plate with tolerable noise and degradation induced by neutrons and gamma radiation.This action is carried out at the Plasma Science and Fusion Technology group of the University of Seville in close collaboration with the ITER Organization, EUROfusion Consortium and JT-60SA teams. It includes two two-month secondments at QST (Japan) to install and exploit the JT-60SA FILD. Trough the execution of this project, the candidate will be trained to lead a research group of engineers and physi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Fourth generation photocatalysts: nano-engineered composites for water decontamination in low-cost paintable photoreactors'.

assistant: **Concept**

The project 4G-PHOTOCAT allies the expertise of 7 academic and 3 industrial partners from 5 EU countries (Germany, United Kingdom, Czech Republic, Poland, and Finland) and 2 ASEAN countries (Malaysia and Vietnam) for the development of a novel generation of low-cost nano-engineered photocatalysts for sunlight-driven water depollution. Through rational design of composites in which the solar light-absorbing semiconductors are coupled to nanostructured redox co-catalysts based on abundant elements, the recombination of photogenerated charges will be suppressed and the rate of photocatalytic reactions will be maximized. In order to achieve fabrication of optimal architectures, advanced chemical deposition techniques with a high degree of control over composition and morphology will be employed and further developed. Furthermore, novel protocols will be developed for the implementation of the photocatalysts into a liquid paint, allowing for the deposition of robust photoactive layers onto flat surfaces, without compromising the photoactivity of immobilized photocatalysts. Such paintable photoreactors are envisaged particularly as low-cost devices for detoxification of water from highly toxic persistent organic pollutants which represent a serious health issue in many remote rural areas of Vietnam and other countries. The 4G-PHOTOCAT project will provide novel scientific insights into the correlation between compositional/structural properties and photocatalytic reaction rates under sunlight irradiation, as well as improved fabrication methods and enhanced product portfolio for the industrial partners. Finally, 4G-PHOTOCAT will lead to intensified collaboration between scientists working at the cutting edge of synthetic chemistry, materials science, heterogeneous photocataly
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Investigation of the Viability of MEMS Technology for Boundary Layer Control on Aircraft' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

The recent development of micro-machining technology has made possible the fabrication of Micro Electro Mechanical Systems (MEMS) where arrays of sensors and actuators having dimensions of a few tens of microns can be integrated with distributed controlling electronics. These advances in technology open up the possibility for a wide range of smart materials". Individual sensor devices based on micro-fabrication are now finding application within everyday engineering products but the use of structures that employ distributed systems of sensors, actuators and integral control systems are only just being investigated. One potential application of MEMS is the control of the boundary layer flow close to the external surface of an aircraft. The ability to control such flows has the potential to lead to very large improvements in efflciency and performance resulting in dramatic reductions in fuel consumption and pollution. This will give rise to significantly increase product competitiveness. Research into this potential application has begun in the USA but as yet little co-ordinated progress has been made within Europe. The current expert understanding of the state-of-the-art, within the partnership, is that there is the potential for a MEMS based flow control system to be incorporated on a production aircraft within the medium term. Many questions still remain to be answered if this goal is to be achieved and it is felt that both confidence in and awareness of the potential application of MEMS within the aerospace industry needs to be boosted. It is therefore considered opportune to initiate a programme of basic research to answer some of these questions and provide a basic demonstration of the viability of this technology. The primary aim of this research project is to asse
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Steering group for clean electricity and heat production with co-utilisation of biosmass and coal and reduced carbon dioxide emissions (PHASE 1) - (CLEANSTEER A)' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

The aim of this Accompanying Measures project is to establish a Steering Group that will provide Support for the Programme Managers dealing with large-scale electricity and heat production, CO2 emissions reduction and the co-utilisation of biomass with other fuels. The steering group will be composed of very experienced people from industry, academia and other research providers who have a broad strategic view of interdisciplinary, international and large scale co-operative R&D. The intention is to assist in ensuring that the operational and strategic objectives of the programme are achieved by developing project clusters, providing for effective linkage between projects, and giving pro-active tactical and strategic advice to aid programme planning.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'ANTI-COLLISION AUTONOMOUS SUPPORT AND SAFETY INTERVENTION SYSTEM. RESEARCH INTO OPTIMALLY ASSISTED DRIVING SYSTEMS AND TECHNOLOGY DEVELOPED FOR EUROPEAN ROADS'.

assistant: **Innovation**

This project will develop and test autonomous vehicle control and driver warning systems to support drivers especially in critical situations (danger of collision). The system, which builds on results from previous European research activities, will demonstrate collision avoidance warning and emergency interventions mechanisms acting along the longitudinal axis of the vehicle. On the basis of user requirements, which will also take into account the needs of elderly and disabled drivers, demonstration vehicles incorporating technologies such as microwave radar and computer vision will be built. The project will also examine the achieved benefits in terms of increased safety and will consider issues related to the future market introduction of such systems.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Unraveling the Epigenetic Arms Race Between Plants and Pathogens' to be submitted under Horizon Europe.

assistant: **Abstract**

Plant-pathogen interactions are complex processes involving molecular and physiological changes in both the host and the pathogen. An increasing number of reports are pointing towards the role of epigenetics in plant defense against pathogens. However, several gaps currently prevent us from fully understanding the extent of chromatin changes as well as their functions during infection. We recently showed that a bacterial virulence factor induces global changes in DNA methylation. My research group also discovered that genes encoding epigenetic factors typically expressed solely during the reproductive phase of the plant life cycle are induced by pathogen infection (abbreviated “RePat” genes). Surprisingly, mutations affecting RePat genes reduce infection suggesting that RePat genes enhance susceptibility to the pathogens. Here, I hypothesize that pathogens hijack the expression of RePat genes to counter-act the innate plant epigenetic defense. In EPIPAT, I will determine the precise spatial and temporal changes in epigenetic marks during infection. We will investigate how RePat genes are induced during infection as well as characterize their function in regulating the epigenome during infection. In EPIPAT, I aim to shed light on a neglected battlefield of host/pathogen interactions, the epigenetic arms race between plants and pathogens. EPIPAT will generate essential data and insights that will open the field's understanding of how epigenetic changes contribute to the plant's defense. The induction of reproduction-specific epigenetic factors during infection suggests that similar nuclear reprogramming mechanisms might be at play in both situations. Exploring their role during infection is bound to provide invaluable insights into their role during reproduction and help
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Boosting Life Cycle Assessment Use in European Small and Medium-sized Enterprises: Serving Needs of Innovative Key Sectors with Smart Methods and Tools' (2007-2013) targeting Seventh Framework.

assistant: **Abstract**

"LCA to go"" develops sectoral methods and tools for bio-based plastics, industrial machinery, electronics, renewable energy, sensors and smart textiles. These sectors have been chosen, as the manufacturers show a high interest in making clear the environmental benefits of their products to customers (""Green industries"") and in prioritizing so they can reduce their environmental impacts. This is particularly the case for SMEs. Free webtools (""apps"") will serve dedicated needs of these sectors, addressing the specifics of the technologies and implementing parameterised models, such as calculators for energy-break-even-point of photovoltaics, Product Carbon Footprints (PCF) based on technology parameters of printed circuit boards, and Key Environmental Performance Indicators (KEPIs) for smart textiles. Selected Product Category Rules will be developed to provide a robust LCA guidance for SMEs. Practically, the project website will provide an exchange of scientifically validated data templates, to assist SMEs to pass the right questions to their suppliers. Carbon Footprints are a perfect entry point for SMEs to LCA strategies. Thus, implementation of an SME-compatible PCF methodology is a key element of the project. The approaches will be tested in 7 sectoral case studies, involving suppliers, end-product manufacturers and engineering companies. Inter-linkages between the sectors (on a technical and data level) will be thoroughly addressed. A broad dissemination campaign includes a mentoring programme for 100 SMEs, which will act as showcases for others, boosting use of LCA approaches among European SMEs at large. RTD and dissemination activities will be complemented by policy recommendations and liaison with standardisation activities. The web-tools, being compatible
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Harnessing Monte Carlo simulation to improve the accuracy of dose delivery in eternal-beam radiotherapy' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Research objectives and content The Monte-Carlo (MC) metllod enables computer simulation of the particle tracks of radiations such as high-energy photons and electrons through arbitrarily complicated geometries without physical approximations using random numbers and atomic cross-section data. The extraordinary speed and affordability of today's computers makes such MC-based simulation a realistic basis for radiotherapy treatment planning. I will be using the well documented EGS4 MC code and writing routines to track particles through the three-dimensional geometry of radiotllerapy accelerators and patient anatomy. The objective is a major improvement in the accuracy of radiation dose delivery in patients undergoing external-beam radiotherapy (roughly I in 7 EU citizens), especially in the highly inhomogeneous thorax and head and neck regions. This worlc is being conducted in collaboration with a treatment planning system manufacturer and will thus result in the widespread use of is new computation method in European cancer clinics. Training content (objective, benefit and expected impact) My background is in dosimetry, radicbiology and MC modelling. Through this project will receive a training at a world-class research centre in the exciting field of MC-based radiotherapy. Linlcs with industry / industrial relevance (22) The scientist in charge is collaboratrogYadh DOSIGlLlY, a french StIE vnth a major European market share in radiotherapy treatment planning systems (l PS). The resulting Monte-Carlo-based TPS should be a world first.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Biocompatible nanoparticles for T cell targeted siRNA delivery as novel asthma therapy' in the context of a Horizon 2020 call.

assistant: **Objectives**

The aim of this proposal is to engineer biocompatible nanoparticles that deliver short interfering RNA (siRNA) to activated T cells (ATCs) for the downregulation of the Type 2 T helper cell (Th2) transcription factor GATA-3. By downregulating GATA-3 with siRNA, which regulates the secretion of proinflammatory cytokines in chronic inflammatory diseases such as asthma, the activation of their downstream inflammatory cascades can be prevented. However, T cells are hard-to-transfect cells which are not readily accessible for nucleic acid based therapeutics. I am the first to have demonstrated successful and targeted siRNA delivery to ATCs ex vivo and in vivo for specific GATA-3 knockdown without delivering siRNA to naive T cells. Thus, I can avoid general immune suppression. This was achieved by engineering targeted siRNA delivery systems based on low molecular weight polyethylenimine (LMW-PEI) which form nanoparticles with siRNA and successfully deliver the latter to ATCs. The targeting approach was realized by coupling transferrin to LMW-PEI and by optimizing the coupling chemistry. I have demonstrated specific delivery to ATCs in a mouse model of allergic asthma and have screened siRNA sequences for efficient GATA-3 knockdown. The nanoparticles were administered locally to the lung to prevent the first-pass effect in the liver. The LMW-PEI based nanocarriers were very well tolerated in healthy animals, however, potentially caused additional proinflammatory effects in the asthma model. Therefore, I will engineer nanocarriers that do not only specifically deliver siRNA to ATCs but are also biocompatible in a diseased state of the lung. I will use oligospermines, which are tetramers and octamers of spermine, an endogenous polyamine, and apply the optimized coupling strategy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'EmpoweRing FundamEntal physics and Technology with quantum Optomechanics'.

assistant: **Objectives**

The recent advancement in quantum technologies and control raises the fascinating possibility to employ them for developing a whole new generation of devices based on the laws of quantum mechanics. At the same time, such progress enables unprecedented studies on the foundation of quantum mechanics and the quantum nature of space-time. This is precisely the overreaching goal of this action, which we dub pERFEcTO, that will use the technological platform embodied by quantum optomechanics to address alternative formulations of quantum mechanics and quantum spacetime effects. Hybrid optomechanical systems and novel quantum estimation methods, which have recently attracted great interest, will be exploited due to their adaptability to the different scenarios addressed by pERFEcTO. The aim is to develop optimal estimation tools and strategies adapted to hybrid optomechanical systems in order to investigate quantum foundations and (quantum) spacetime models. Furthermore, the action will extend such a study all the way to the addressing of out-of-equilibrium thermodynamics of hybrid optomechanical systems to characterize the quantum-to-classical transition in these systems and explore their potentiality for engineering quantum thermal machines. The action envisions the collaboration with experts from academia through three secondments at leading European research institutes and is set to expand scientific, transferable and collaborative skills of the Experience Researcher.pERFEcTO embodies an innovative approach to key fundamental problems and, through an intensive training programme, significant dissemination activities, and effective knowledge transfer paves the way for the career development of a talented young researcher who has already proven a solid track record of scient
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'To the roots of induced systemic resistance in the Arabidopsis-Trichoderma-Fusarium tripartite interaction'.

assistant: **Innovation**

Biological control organisms (BCOs) can form an important component of more sustainable agriculture. Trichoderma spp. are soil fungi with great potential in this respect. They can trigger induced systemic resistance (ISR) in the plant, leading to a more rapid and robust systemic activation of defense when the plant is subsequently challenged by a pathogen. However, genome-wide investigations of the tripartite plant-Trichoderma-pathogen interaction are scarce, although they provide substantial novel information to improve our understanding of ISR and form the basis for development of rational disease management options. In addition, root responses have been neglected despite the fact that they are the first point of contact for soil microbes and drive above-ground plant responses. The research objective of this project is to identify the defining plant responses originating in roots that drive the ISR process in the Arabidopsis-Fusarium-Trichoderma interaction. This will be achieved by a comparative genomics study of the tripartite interaction in Arabidopsis roots, with Fusarium as soil-borne plant pathogen (core expertise of outgoing host CSIRO Plant Industry Brisbane, Australia) and Trichoderma as BCO (core expertise of return host CPMG, KU Leuven, Belgium). The unique character of this project is to bridge research domains on Trichoderma and Fusarium plant responses, thereby focusing on the largely unknown processes that take place in plant roots. Novel expertise on this interaction will be acquired during the outgoing phase and transferred to the ERA for implementation at the return host institute, in collaboration with the outgoing host and afterwards also other ERA laboratories, to the benefit of biocontrol research in general. In addition, the project foresees a t