RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Information technology for adoption and intelligent design for E-Government' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

One of the great challenges for European governments is solving the paradox of increasing security of international trade, while at the same time reducing the administrative overhead for commercial as well as public administration organisation. It is vital to have timely information about business transactions. This information gathering is very costly for businesses and public administrations. Finding the right balance between control and cost of information gathering is the key to increase competitiveness of European businesses locally, nationally and internationally.ITAIDE develops a Common Information Model for electronic documents and document mapping software to improve the pan-European interoperability of taxation and customs systems. This interoperability is an essential prerequisite to achieve strategic goals for e-customs such as the introduction of Authorised Economic Operator and Single Window Access service provisioning for businesses. ITAIDE develops a procedure redesign methodology, supported by an intelligent software tool, to improve the efficiency and simplification of e-customs procedures. To encourage the adoption of these redesigned procedures by Taxation and Customs offices, businesses and technology providers, it should be the result of a truly collaborative co-design process that creates win-win benefits for all these stakeholders.This requires new public-private partnerships between Taxation and Customs offices and businesses. We also develop organizational network collaboration models to build these new public-private partnerships between Taxation and Customs offices and businesses. ITAIDE integrates and strengthens European research for innovative government by enhancing service offerings and disseminating good governance practice through incr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Theoretical studies of chemo-mechanical instabilities in soft materials: self generation of rhythms and forms'.

assistant: **Innovation**

Chemical dissipative structures have played a key role in the development of self-organization science. Our objective is to go beyond the well-known reaction-diffusion instabilities, to a new class of patterns and autonomous motions driven by chemical energy in active soft materials. They result from chemo-mechanical instabilities emerging from the coupling of chemical kinetics with shape changes induced by the chemical concentration field in deformable soft porous media, used as support for the reaction.The necessary non-linearities originate either from the chemical kinetics or from the geometric response of the material to the concentration of some chemical species. In Bordeaux, recent experiments, which couple an acid autocatalytic reaction to a pH-responsive gel, evidence new sources of instabilities triggered by mutual feedback between the gel size and the chemical processes. A comprehensive model accounting for the transport, for reaction, and for the distributed mechanical properties of a responsive gel is still lacking.The derivation and numerical investigation of such a model are our main objectives. Chemo-mechanical systems may be used as delivery devices, pumps working with the energy from their environment, or as autonomous valves, sensing the concentration of specific molecules and triggering an active response. The search for chemo-mechanical instabilities is also expected to enlighten phenomena in living organisms by bringing new insights in embryo self-shaping, active response of tissues to mechanical stress, or in some forms of motility. This proposal can make a major step in understanding chemomechanical instabilities, a new field at the interface between non-linear physical chemistry, soft matter, and biomimetics.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Upgrading Cyanines dyes: Non-Kekulé ketocyanines and related patterns' (KETOCYAN) under Horizon 2020.

assistant: **Objectives**

The scientific goal of KETOCYAN is to renew classical nitrogen-containing polymethine dyes, so-called cyanines, and transform them into suitable tools for tackling the modern challenges of photoredox chemistry. The flagships for the proposed molecular patterns are unusual “non-Kelulé” diradicaloids. In principle their exotic topology must result in remarkable properties, including near-IR absorption, redox activity, enhanced photo-stability, etc. However, the unusual structures have also long been regarded as non-viable synthetic targets. This traditional belief has been challenged by recent reports and preliminary results of the host team. The project intend to capitalize on this paradigm shift, to develop synthetic methodologies, to study the novel organic functionalities, up to the design of original families of diradicaloid redox-active organic dyes.The fellow, Eder Tomas-Mendivil, is a seasoned synthetic chemist with solid track record and expertise in organometallic and organic chemistry, including the design and synthesis of unusual and/or reactive compounds. The host laboratory, the academic environment and the infrastructures at Université Grenoble Alpes will provide complementary training and experience, including in electrochemistry, photophysics, DFT calculation or study of radicals, but also in research management and communication. Overall this action will provide the fellow for outstanding career development opportunities, with a focus on academia.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Acoustic emission applied to mechanically loaded paper' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The paper industry is one of the most rapidly changing industries today. Driven by the pressures and demands of Information Technology, its products must meet ever greater demands placed upon it by the customer, involving new paper types and qualities, new requirements for physical properties and behaviour, etc. The problem is that more has to be understood about the complex physical and mechanical properties of paper and its constituents to enable new paper qualities and products to be 'designed'. This project will apply the tool of Acoustic Emission to the material specifications of the paper fibre, its characterisation as well as fibrous networks with the aim of developing new or improved end products. Acoustic Emission is a well-known technique for metals and polymer composites and has shown promise for paper, but has never been systematically investigated or exploited.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Structurally Engineered 3D Printed Architectures for Scalable Tissue Engineering' to be submitted under Horizon 2020.

assistant: **Abstract**

Engineering tissues with a hierarchical vascular network, which is the goal of our ERC project VascArbor, is challenging. Developments in the field of biofabrication, including 3D bioprinting, are promising to cope with this challenge. However, current strategies lack the capacity to create hierarchical, high resolution, cost efficient, upscalable constructs in a standardized manner with a single approach. Embedded bioprinting, allowing the deposition of complex constructs without the need of a supporting substrate, provides a potential solution. However, embedding baths used so far consist of inert materials and therefore cannot become a functional component of the tissue. Also, the embedding bath should be patternable to allow for multistructural tissues, but printing of the bath itself is currently challenging due to clogging of the nozzle.SE3DPASTE will develop a dehydrated precursor of a free standing embedding bath that is storable for “off-the-shelf” use and tissue specific. Additionally, SE3DPASTE will develop a bespoke 3D printing nozzle that will allow for the creation of patterned embedding baths. SE3DPASTE will lead to storable, transportable, tissue specific embedding baths that act as a patterning template and can be used for embedded bioprinting of tissue. This combination of features, which does currently not exist in embedding baths for 3D printing, will be a key enabler for the generation of standardized 3D tissue environments that lead to predictable tissue development for research-, clinical-, or drug screening purposes.SE3DPASTE will not only develop the technology to make this possible, but will also take vital steps to bring this technology to the market. By securing the IP, and analyzing the market and the willingness of investors to support SE3D
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Ceftiofur Long Acting to Reduce Antibiotics'.

assistant: **Concept**

The Ceftiofur Long Acting to Reduce Antibiotics (CLARA) is a new technology project for large animal pharmaceutical products with one shot, long acting treatment, based on a widely recognized molecule. It will result in a long acting antibiotic injection process (one shot / 7 to 8 days) of Ceftiofur to treat farm animals against important infectious diseases on respiratory and digestive systems, with a very short delay. This new technology for delivering antibiotics will help to: reduce the quantity of antibiotic delivered, reduce the number of injection or delivery, improve tolerance for animals and improve food chain safety. So-called Hydrogels, obtained through hydratation of high technologies polymers (PLA and PEG), will be the base of the technology for this innovation. Small and Medium Sized Enterprises participating to the project will have a total control on the Project Results property and on the dissemination process. As the project is completely SME and industry driven, there is also a unique commitment to disseminate the veterinary products resulting of the project in every European country and, to diffuse them on the worldwide market with great opportunities on emerging and fast growing markets (Asia and Pacific). The project starts from pure R&D actions to clinical fields trials to control efficacy of the candidate product on the targeted species. After the project end, the Coordinator, on behalf of the Consortium and in the interest of participating SMEs, will reach a pan-European registration through central or decentralized registration in all the Member States to deliver quickly the new product to the animal health market through. The Consortium includes Animal Health Pharmaceutical SMEs individually recognized as references in their respective country
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Multi-Dimensional Lab-On-Chip' under Seventh Framework.

assistant: **Concept**

There are several bottlenecks that hinder certain aspects of proteomics, in particular, incompatibility of high throughput technologies with certain protein types or modifications, low sensitivity and lack of quantitative data. I have developed a microfluidics affinity assay compatible with transmembrane proteins and post-translational modifications that is highly sensitive and can provide quantitative data.The primary objective of this proposal is to bioengineer, using the abovementioned building blocks, a multi-functional microfluidic-based human protein arrays. The platform will enable addressing important scientific questions not otherwise possible. Specifically, the process of DNA demethylation, which is poorly characterised due to technological limitations. The biological aspects of chromatin methylation and their regulators that are crucial for cell differentiation and disease will be studied.Work in MuDLOC will include the following: i) Bioengineering of a microfluidic-based platform that expresses thousands of human genes; ii) Design new tools for post-translational modifications and chromatin modifications; iii) Search for chromatin modifiers and their regulators; and iv) Exploration of specific inhibitors using a microfluidic inhibitor screen.Beyond studying chromatin methylation from a new perspective, MuDLOC will greatly benefit a plethora of disciplines, such as proteomics, genomics and cancer research. At the end of the project my vision is to capture under one platform a whole pathway, including protein interactions, post-translational modifications and chromatin modifications.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'small Electric Passenger vehicle with maximized Safety and Integrating a Lightweight Oriented Novel body architecture' in the context of a Seventh Framework call.

assistant: **Objectives**

As the global population gravitates towards increasingly large urban agglomerates, the density of movements and the sheer numbers of people displacements is growing so fast that existing vehicles for personal transport increasingly seem insufficient: consuming too much energy (present day cars), or exposing their drivers to larger-than-needed accident risks (motorcycles or bicycles). As especially urban climate is heating up worldwide, acclimatised personal transport is getting more and more the norm, as opposed to taking a bicycle to work. Epsilon aims to conceptualize, develop and prototype a new category of vehicle in between the ultra compact (urban) car and present day moped category small covered vehicles or semi-covered scooters. Epsilon underwrites the 'hard' performance targets defined in the call topic and seeks to meet these while ensuring a very competitive level of affordability and safety. Epsilon can achieve this by means of leveraging the substantial amount of previous and parallel (national & EU-funded) R&D of other projects in which epsilon partners participate, combined with the specific skills and expertise of the consortium members. As such it focuses on optimally integrating cutting edge yet available on prototype level components, materials, manufacturing technologies and subsystems into a drivable prototype plus 2 crash tested body structures. The extensive real experimental testing in combination with advanced performance simulations will allow full confidence verification of the performance of the vehicle and also will allow for strong promotion of the accomplished innovation. Epsilon takes very serious care of the fit between vehicle classes as agreed in European and worldwide standards and the characteristics of the vehicle to be developed. T
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Systems Genetics of Obesity and Related Metabolic Traits in Pig Model to Improve Human Health' to be submitted under Seventh Framework.

assistant: **Abstract**

The SysGen of Obesity project aims to use the pig as an animal model to unravel genes affecting human obesity, metabolic syndrome and diabetes (OMSD) traits and to catalogue their functional and molecular interactions and biological pathways. It uses state-of-the-art technologies and analytical approaches. The animal model uses a pig population of over 500 third generation progeny derived from crossing very divergent parental breeds (lean and fatty). It thus provides a very powerful design to map genes affecting OMSD. The resource population will be phenotyped for many traits including blood profiles known to be relevant to OMSD. Genotyping will be based on the Porcine 60k Illumina SNPchip. Gene or quantitative trait locus (QTL) mapping and genome-wide association studies (GWAS) will be conducted to detect genes and variants affecting OMSD traits. These genes will subsequently be validated for biological relevance using systems genetics approaches. They will also be screened for concordance with human QTL-GWAS results by comparative genomics. The most significant genes from the above steps could harbour relevant causal genes/mutations and hence will be selected for targeted resequencing and further analyses. This animal model is also expected to find 'novel' genes and pathways that have not been identified previously in human obesity. Systems biology experiment is planned using a ‘BioBank’ of relevant tissues and RNA samples from this resource population. The ultimate impact will be in the form of delivery of potential causal mutations, biological pathways, genetic- and bio-markers and new drug targets to improve human health. Hence our project will enhance EU excellence in Genetics and Systems Biology of OMSD and strengthen EU bio-medical industry. This grant will give
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Development plasma technology continuous processing textile fabrics nonwovens plasmatex' in the context of a Fourth Framework call.

assistant: **Objectives**

The analytical and experimental work of this project has resulted in following achievements: 1. A book of specifications has been developed containing industrial end-user's commercial process requirements concerning the potential advantages of plasma treatment on textiles and nonwovens.2. The investigations have been made of experimental plasma systems able to replicate and characterise target industrial processes achieved by low-pressure plasmas. Diagnostic systems for both low-pressure and atmospheric-pressure plasma types have been developed.3. Transfer to know-how from low-pressure to atmospheric-pressure systems has been made using test materials from the industrial partners. Samples received from the end-users have been treated in low-pressure plasmas and analysed and application tested. Atmospheric-pressure plasma process characterisation has been made of representative samples received from the end-users.4. Mathematical modelling of the plasma processes for producing the target results have been developed.5. Milestone M1 has been reached as explained below.Successful processes have been demonstrated in static regime with samples from three and-users, and in dynamic regime with PP fabric at speeds of 4m/min. The materials chosen (PET, PP and cellulose) are representative of the spectrum of fabrics used by all end-users. Treatment in dry air, argon and helium have been successful.In conclusion, the ability of lab plasma processes to solve target industrial problems has been successfully demonstrated (M1).6. Milestone M2 has been reached as explained below.Characteristics of successful processes demonstrated in M1 have been well recorded. Plasma fingerprints and data libraries (built during T5 and T6) can be successfully used to simulate processes of M1.The process