RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Network Fairness: A novel complex network approach for tackling inequalities in society and algorithms', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Social inequalities are on the rise and will have devastating impacts on education, healthcare, economiesand societies for many generations to come. Structural barriers to equality, despite being complex and dynamic,are poorly understood through the lens of complex evolving social networks. More crucially, withthe rise of AI and machine-learning algorithms, it is extremely important to detect, forecast, and mitigatethose inequalities in a systematic manner in order to avoid unintentional algorithmic consequences.A network fairness framework is proposed, premised on topological and temporal features of social interactionsthat shape the formation and evolution of inequalities. These features include (1) people havemultiple and correlated attributes that determine how they identify with groups and interact with others,(2) people belong to a variety of social groups with different sizes, hierarchies, and historical precedents,and (3) interactions between people evolve over time in a hybrid space of society and algorithms.To this end, I will develop a suite of dynamical complex network models of inequality that are driven bysocial theories (e.g., homophily, intersectionality, consolidation) and calibrated and evaluated with big dataand network experiments. This will allow us, for the first time, to investigate inequalities that arise fromnetwork-based algorithms in a systematic manner. More importantly, I will devise a novel methodology ofnetwork intervention, a set of data-driven principles for tackling network inequalities in a broad range ofapplications. Finally, based on the models developed in this project, I will create a cutting-edge interactivesoftware – NetFair – to visualize and forecast the evolution of inequalities and implement various fairnesscriteria. The soft
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Coherent, frequency multiplexed light source'.

assistant: **Innovation**

The heart of the system will be an optical parametric oscillator (OPO) driven by a diode-pumped solid-state laser. The output of the OPO will in turn be frequency doubled in a broadband quasi-phase-matched (QPM) device. Around the centre wavelength the device will be able to quickly select at random anyone of hundreds of discrete optical frequencies, each used to write or read a hologram (a page of information of the order of 1 Mbyte). Combined with spatial multiplexing, where the device optically or mechanically addresses consecutive volumes, storage of several Gbytes of information will be possible.The project concerns a coherent, frequency multiplexed light source with an absolute frequency reference and the ability of fast random switching between a set of discrete frequencies. Such a source would have great importance for future optical mass information storage devices, as frequency multiplexing of optical holograms offers potential advantages over the more commonly proposed angular multiplexing, and the related components have the potential for a high degree of integration and low cost.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Extending the use of existing on-line turbine washing technology to large 50MW gas turbine units' under Fourth Framework.

assistant: **Concept**

THE SCIENTIFIC & TECHNICAL OBJECTIVES OF THIS RESEARCH Project ARE TO SOLVE THE PROBLEMS ASSOCIATED WITH SCALING-UP THE PRIME PROPOSER'S EXISTING ON-LINE GAS TURBINE WASHING TECHNOLOGY NOW BEING USED ON A NUMBER OF 5MW TO 25MW UNITS. THIS WILL ENABLE THE INNOVATIVE CONCEPT OF ON-LINE GAS TURBINE WASHING TO BE PROMOTED TO MANUFACTURERS & OPERATORS OF LARGE 50MW TO 300MW GAS TURBINES IN ORDER THAT THEY TOO WILL BE ABLE TO A) MINIMISE OFF-LINE MAINTENANCE PERIODS & B) CONTINUOUSLY INHIBIT THE ACCRETION OF OUTPUT REDUCING DEPOSITS - BENEFITS WHICH WILL MAXIMISE OPERATIONAL EFFICIENCY &: REVENUE EARNING POTENTIAL.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Route to On-Chip Resonating Optical Clocks via Nonlinear Optics'.

assistant: **Objectives**

“Measure what is measurable, and make measurable what is not so” (Galileo). Optical frequency comb sources are devices capable to emit light with a comb spectrum composed by narrow lines (i.e. colours) with a fixed frequency spacing.  Their introduction gave to Science powerful clockworks capable to measure the frequency of the light and create ultrafast clocks with unprecedented accuracy, unveiling new science in astronomy, geology, biology and many other fields. Their importance in optical metrology has been recognized in the 2005 Nobel Award to T. W. Hänsch. The possibility to miniaturize these sources with strategies meeting the requirements of current electronic platforms would not only produce cheap and low consumption optical sources for ultrafast optical communication and metrological applications, but could bring a greater revolution in the current microchip technology, promoting a “photonic transition” of microelectronics. The recent realization of optical frequency comb sources by exploiting miniaturized resonators represents a fundamental advance towards this direction. However, the impact of these optical sources depends on the full understanding and control of their spectral phase: only when this control is achieved, these devices can be effectively exploited as ultrafast optical clocks. A mode-locking mechanism shaping the phase toward pulse generation was only recently tackled by the applicant and appears a viable solution: this scheme consists in embedding a nonlinear micro-resonator in a fibre laser cavity.  It can be considered the precursor of a family of devices implementing phase control by exploiting nested cavities with different nonlinear roles. This project addresses in details this new class of designs, starting from the underlying physics, ta
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Integrated High-speed Power Systems for Industry and Mobile Applications'.

assistant: **Innovation**

This DN implements a multidisciplinary and innovative research and training programme, bringing together different scientific fields and industrial participation to enable a new generation of Doctoral Candidates (DCs) to investigate and develop electric drives in the context of electrification in the transition towards zero-emissions. Electrification is one of the key assets in green transition and future sustainable world.While electrification offers one of the main solutions in reaching carbon-neutral societies, there is already now a lack of skilled persons in the field. Therefore there is an urgent need to educate young highly skilled engineers with a breadth of interdisciplinarity on designing propulsion machines and power converters to become EU’s future leaders in power electronic systems (applied in renewable energy systems and electric vehicles - EVs). The proposed network is timely in meeting the challenges, bringing together the leading experts and providing best training opportunities to doctoral candidates (DC). This will make a step change in the EU’s key industry with potential impacts on other applications such as high-speed trains, electric vehicles, electric aircrafts and ships.High-speed technology enables high material and energy efficiency. Therefore, HIPO (integrated HIgh-speed POwer systems for industry and mobile applications) research and training programme will focus on providing Doctoral Candidates (DCs) with relevant knowledge, methods and skills across a wide range of disciplines around Electric High-Speed Drives.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Mathematical Thermodynamics of Fluids' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The main goal of the present research proposal is to build up a general mathematical theory describing the motion of a compressible, viscous, and heat conductive fluid. Our approach is based on the concept of generalized (weak) solutions satisfying the basic physical principles of balance of mass, momentum, and energy. The energy balance is expressed in terms of a variant of entropy inequality supplemented with an integral identity for the total energy balance.We propose to identify a class of suitable weak solutions, where admissibility is based on a direct application of the principle of maximal entropy production compatible with Second law of thermodynamics. Stability of the solution family will be investigated by the method of relative entropies constructed on the basis of certain thermodynamics potentials as ballistic free energy.The new solution framework will be applied to multiscale problems, where several characteristic scales become small or extremely large. We focus on mutual interaction of scales during this process and identify the asymptotic behavior of the quantities that are filtered out in the singular limits. We also propose to study the influence of the geometry of the underlying physical space that may change in the course of the limit process. In particular, problems arising in homogenization and optimal shape design in combination with various singular limits are taken into account.The abstract approximate scheme used in the existence theory will be adapted in order to develop adequate numerical methods. We study stability and convergence of these methods using the tools developed in the abstract part, in particular, the relative entropies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Allosteric modulation of G-protein Coupled Receptors conformational landscape' under Horizon 2020.

assistant: **Concept**

G protein-coupled receptors (GPCRs) are the largest family of transmembrane receptors in eukaryotes. They bind a wide range of ligands, such as neurotransmitters, hormones, lipids and many others. GPCRs are the target of more than 30% of the drugs currently on the market, addressing neuropsychiatric, cardiovascular, pulmonary and metabolic disorders, cancer, obesity and AIDS. The functional versatility of GPCRs cannot be explained by a simple two-state model of activation considering only an active and an inactive state, as these receptors are highly dynamic and can explore a wide range of conformations. Some receptors of the family can signal in the absence of ligand (basal activity), and despite GPCR have been largely studied in the past years, little is known about their signal transduction mechanism. Apart from ligands and signalling partners, the structure and function of GPCRs can be modulated by lipids. In this context, our research will be divided in two steps: delineating the role of lipids on GPCR conformational landscape at the molecular scale (Aim1) and exploring an additional allosteric factor in line with lipid composition, the homo- and hetero-receptor oligomerisation (Aim2). To that purpose, we will apply an integrated, multidisciplinary analysis, to characterize protein dynamics under physiological conditions, with the GPCR reconstituted in model lipid systems or living cells, and in the presence of ligands, signalling and regulatory partners. We will use conformational probes to investigate the effect of lipids and other GPCRs on receptor dynamics, and correlate these findings with functional properties such as agonist binding and G protein coupling.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Opto-Electronic Neural Connectoid Model Implemented for Neurodegenerative Disease'.

assistant: **Objectives**

A major challenge facing Europe is its ageing population and associated increase in diagnosed cases of neurodegenerative diseases (NDD). Parkinson’s disease (PD) is associated with tremor and loss of motor functions due to progressive degeneration of dopaminergic neurons in the brain. This can lead to memory loss and dementia, which is associated with short- and long-term injuries and disabilities with emotional, financial, and social burdens for patients, families, and society. The exact causes and mechanisms underlying PD are still unknown and existing treatments focus on alleviating symptoms and increasing quality of life, but do not halt or reverse disease progression. Although animal models give unique possibilities to study physiological and behavioural mechanisms, drug development fails due to lack of translation to humans. Alternative non-animal NDD models is needed both in terms of better translation, but also to replace expensive and problematic animal experiments.We will move disease modelling to a new level and replace animal models, by creating a new concept we call connectoids. We will develop an ex-vivo-type in vitro human opto-electronic multi-regional brain-organoid disease model in which connectoids are formed by precise spatial arrangement of brain organoids connected via hydrogel tracts that promote axonal pathfinding, functional connection, and signalling. By developing 1) light controllable sub-type specific neurons within regionalized brain organoids, and 2) electrodes and waveguides that can penetrate the organoids able to monitor neurotransmitter signalling inside and between the organoids, we will for the first time be able to sense how a particular brain region responds to a certain therapy and watch in real time how signals are transmitted to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Intact SynaPtic Imaging in REal-time' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Modern fluorescence microscopy can provide rapid, real-time functional imaging of brain activities (light sheet) or to visualize with high definition and specificity the synaptic organization (super resolution, expansion). However, rapidity and precision are still too far apart to allow studies of fast dynamics with intra-synaptic precision mainly due to incompatible optical and probes requirements in current technologies. My aim is to fill this gap with the development of an optical platform, named InSpIRe, which allows real-time volumetric imaging of brain tissues with intra-synaptic level of details thanks to a new optical scheme coupled to the photo-switching properties of recently engineered red-shifted probes. InSpIRe will take advantage of rsFusionRed, a new palette of reversibly switching fluorescent proteins, which we recently introduced. The contrast and photo-resistance of rsFusionRed imaging will be increased with an optical strategy that uncouple the geometry of the illumination for switching and fluorescence excitation, which we demonstrated in our MoNaLISA microscope. In InSpIRe these concepts are brought to a new level to record volumetric dynamics in brain tissues without compromising resolution and speed. We will craft a new interference pattern, which optically imprint small-sub-resolved- volumes of rsFusionRed in the 3D tissues architecture. These volumes will be read-out with an oblique sheet of light to increase speed and minimize photo-bleaching. Unlike lattice light sheet we use one objective lens, which increases the slice accessibility and unlike STED/STORM the acquisition is faster. InSpIRe will record movies with molecular resolution without losing the larger neuronal architecture, which can shine light to open question in the field of organe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'GEroNIMO: Genome and Epigenome eNabled breedIng in MOnogastrics', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

To face human population growth, increasing environmental constraints and changes in socio-cultural values, animal breeding must evolve toward a more sustainable model that guarantees production while promoting efficient resource use, animal health and welfare, and preserving genetic diversity. Thanks to recent developments in omics technologies, it is now possible to rethink breeding, taking advantage of improved knowledge on genome-to-phenome relationships that accounts for both genetic and non-genetic mechanisms controlling traits. GEroNIMO will work on chicken and pig, the most used sources of animal protein worldwide, to provide breeders with new knowledge and tools to promote innovative genome- and epigenome enabled selection methods for traits related to production (quantity and quality), efficiency, productive longevity, fertility, resilience and welfare. A large number of animals from cosmopolitan and local breeds will be characterized phenotypically, genetically and epigenetically under different environments to i) identify underlying biological mechanisms affecting trait variation, ii) develop methods to improve selection strategies integrating genetic- and non-genetic factors, and iii) propose strategies to optimize the conservation of genetic and epigenetic diversity. GEroNIMO proposes demand-driven innovation employing a multi-actor approach through the involvement of breeders, professional associations of animal production, and scientists, engaged from the planning phase to the dissemination of results over Europe. GEroNIMO will build on existing academic and commercial knowledge and will analyze large populations to quantify the contribution of genetic and epigenetic variation in gene expression, trait variation and trade-offs between traits. GEroNIMO wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Facility for aerothermodynamic and propulsion studies' (FAPS).

assistant: **Concept**

Description:FAPS comprises installations hosted by four research laboratories associated in the Research Federation EPEE (Energy, Propulsion, Space, Environment). It is operated by CNRS (Centre National de la Recherche Scientifique) and consists of the following installations;- The Wind-Tunnels for Space Applications (WTSA) are a unique experimental complex used for solving aerothermodynamic problems related to space (atmospheric re-entry, spacecraft control);- PIVOINE is a vacuum chamber equipped with cryogenic pumping to simulate the operating conditions of thrusters in space. It is used for fundamental research on electric propulsion for spacecraft;- Full-size automobiles can be tested in the large Subsonic Wind-Tunnel (SWT). The maximum flow velocity is 60 m/s or 35 m/s depending of the test-section in use. The free stream turbulence level can be adjusted;- The Engine Test Benches (ETB) offer diagnostic tools to measure the exhaust emissions, and investigate the detailed combustion process. They are used for studies aimed at reducing fuel consumption and decreasing pollutant emission;- The installations of the Laboratoire de Combustion et Systèmes Réactifs (LCSR) consist of combustion chambers and reactors, shock tubes, atmospheric chambers, etc. They are used in the field of propulsion, combustion and their environmental effects;- The laser facilities of the Groupe de Recherche sur l'Energétique des Milieux Ionisés (GREMI) consist of various laser sources used both for plasma production and diagnostic. Plasma facilities include a large number of reactors and sources. Advanced diagnostic techniques allow probing various reactive and ionised media of interest in propulsion studies. Under the contract, 16 users received access for a total presence of 1346 days and 58