RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Estimating the effect of ride-hailing on public transportation' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

Uber, Lyft, and other ride-hailing companies have transformed the transportation marketplace in over eight-hundred cities around the world. These firms' entry into cities has been controversial. They have been credited with providing a reliable and affordable transportation option, serving neglected areas of cities, and providing meaningful employment. Against these benefits, however, they have been accused of being unsafe, creating congestion, destroying stable jobs, and flouting the law. Governments have struggled to decide how to regulate these companies, in part because of a poor understanding of the actual impacts ride-hailing is having.The proposed research program will increase our understanding of how ride-hailing is affecting cities. Specifically, the project will estimate how ride-hailing affects public transportation. Theoretically, this is unclear since while Uber is an alternative form of travel, it can also increase the reach and flexibility of public transportation. To measure the effect of UBer on transit, I will estimate how the introduction of new subway stops affects Uber ridership. This will shed light on whether Uber and public transportation are complements or substitutes. This project will use Uber's proprietary data. I have signed a Data USage Agreement with Uber allowing access to their data.The project will be hosted by the department of Spatial Economics at VU Amsterdam, which arguably has the world's leading research group of transportation economists.


**Keywords:** ride-hailing, public transportation, Uber, big data
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Functional Genomic diagnostic tools for coronary artery disease' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

The theme of this proposal is to develop methodologies that integrate functional genomic tools and genetic strategies to address major unresolved questions concerning the molecular basis of common diseases using coronary artery disease (CAD) as an example. Progress in functional genomics technologies have dramatically increased the density of gene expression datasets providing information on the expression of individual genes and gene networks at the levels of transcription, translation, protein abundance and activity, and metabolic processes. They will impact prevalent human complex disorders by providing new information for disease prevention and treatment. Risk factors of CAD represent dominant causes of premature death and disability. Owing to the complexity of CAD, our understanding of the pathophysiological processes involved is limited.In this programme implemented by international investigators and SMEs we shall use functional genomics technologies (metabonomics, proteomics and transcriptomics) to generate a comprehensive and multidimensional description of well-defined states of CAD in selected clinical cohorts and animal models, which will be used as a platform for studying the causes of CAD. We will initially test the power of high- density functional genomic datasets in separating patients from probands and disease models from controls. Subsequent genetic studies will test the inheritance of both classical morphological, biochemical and hormonal phenotypes and quantitative traits derived from functional genomics datasets.This multidisciplinary strategy will ultimately:i) define novel disease causative biomarkers associated with or predicting disease onset and progression andii) provide genetic and genomic information for identifying the underlying genes.This
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Sustainable consumption research exchanges' in the context of a Sixth Framework call.

assistant: **Objectives**

Sustainable consumption and production (SCP) is key policy priority world-wide. In our view, sustainable consumption and production structures can only be realized if experts that understand business development, (sustainable) solution design, consumer beh aviour and effectiveness of (policy) instruments work together in shaping them. Furthermore, this should be linked with experiences of actors (industry, consumer groups, ecolabelling organisations) in real-life consumption areas. Since in the EU a network with these characteristics is absent, this project sets up a Co-ordination action on SCP, emphasizing on user awareness" for sustainable consumption, involving key expertise covering all relevant steps of the value chain in the priority consumption domain s Mobility, Agro-Food, and Energy/electronics. These domains contribute to over 70% of the life cycle impacts of household consumption, are a priority in the EUs Enviromental Technologies Action Plan (ETAP), and give good examples of user awareness schemes (e.g. labeling). The CA is organized around a series of Workshops and Conferences. A first Workshop is will provide a general exchange of views. The second phase of the project gives sustainable consumption cases in the domains centre stage. These are use d as vehicles for a positive confrontation of insights from different science field, leading to true best practice generation, suggestions for implementation of user awareness approaches, research programming, and development of conceptual insights. The sc ience and consumption domains are covered by 8 WP leaders and 21 Participants and will involve a much larger community of SCP experts from industry, government and science. A close liaison with UNEP, promoting a 10 Year Framework of Programs on SCP will be orga
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Wealth Acumination and Inequality in China and its Neighboring Emerging Countries: Trends, Drivers and Policy Implications' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

In the last four decades, China, has experienced exceptional economic growth; its share of global GDP has increased from less than 4% in 1978 to about 20% in 2015. This record growth has moved China from a relatively poor, underdeveloped country to the world’s leading emerging economy. However, due to the lack of national balance sheet data and individual income tax records, relatively little is known about the evolution of income and wealth distribution within China. We know little about how much different sectors or income classes have benefited from China’s growth, as well as the mechanisms driving the inequality trend.Combining national accounts, survey, wealth and fiscal data, this proposed research project aims to address this gaps in literature by: i) providing consistent series on the accumulation and distribution of income and wealth in China in both national and provincial level over the period of 1978-2015, and ii) investigate the potential mechanisms driving the inequality trend. In particular, I will carefully examine three important yet understudied channels which drive the inequality trends in China and its neighboring emerging countries since 1978, namely; privatization, the rising capital share in total income, and the openness of economies to trade and foreign direct investment. This research project follows the literature concerning the long-run evolution of the distribution of income and wealth. In order to be able to compare findings for China with existing inequality studies for other countries, I will build a harmonized framework following the Distributional National Accounts (DINA) guidelines for analyzing aggregated national wealth and inequality. Through four related studies, this proposed project will provide insights into a fundamental questi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Understanding respiratory tract infections through minimally-invasive, daily nasal sampling in children' under Horizon Europe.

assistant: **Concept**

Pneumonia is the number one infectious cause of death in children worldwide. Many of the viruses and bacteria that cause pneumonia regularly infect, or colonize, the upper respiratory tract (URT) without causing disease. This drives community transmission but is also an important source of immunity. The processes and key host immune and microbiota factors that determine the infection kinetics, transmission and development of immunity during such infections need elucidation. I have recently optimized minimally-invasive nasal sampling analysis methods using Synthetic Absorptive Matrix (SAM) strips that now allow me to address these knowledge gaps. Through the daily collection of such well-tolerated nasal samples in children, I will study non-pathological, naturally-acquired URT infections, but also controlled infections in an ethical and safe manner using the live attenuated influenza vaccine. In addition, I will perform high frequency nasal sampling in groups of schoolchildren to precisely measure transmission events over time and even infer exposure. Incoming bacteria, viruses and the resident URT microbiome as well as mucosal host innate and adaptive immune responses will be quantified in parallel throughout infections using existing and new high-throughput assays, including an antigen array and microfluidic qPCR for 32 pathogens. Multi-omics integrative time-series analyses and mathematical modelling will be used to identify parameters that are central and predictive for pathogen acquisition, replication and clearance; as well as for transmission and immune boosting. Key novel markers and concepts will be validated using state-of-the-art in vitro mucosal models.The comprehensive and detailed understanding of URT infections obtained in this project can lead to better d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Conserved Non-Coding Sequences; function, variability and phenotypic consequences', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Comparative genomics revealed that ~5% of the human genome is conserved among mammals. This fraction is likely functional, and could harbor pathogenic mutations. We have shown (Nature 2002, Science 2003) that more than half of the constrained fraction of the genome consists of Conserved Non-Coding sequences (CNCs). Model organisms provided evidence for enhancer activity for a fraction of CNCs; in addition another fraction is part of large non-coding RNAs (lincRNA). However, the function of the majority of CNCs is unknown. Importantly, a few pathogenic mutations in CNCs have been associated with genetic disorders. We propose to i) perform functional analysis of CNCs, and ii) identify the spectrum of pathogenic CNC mutations in recognizable human phenotypes. The aims are: 1. Functional genomic connectivity of CNCs 1a. Use 4C in CNCs in various cell types and determine their physical genomic interactions. 1b. Perform targeted disruption of CNCs in cells and assess the functional outcomes. 2. Pathogenic variation of CNCs 2a. Assess the common variation in CNCs: i) common deletion/insertions in 350 samples by aCGH of all human CNCs; ii) common SNP/small indels using DNA selection and High Throughput Sequencing (HTS) of CNCs in 100 samples. 2b. Identify likely pathogenic mutations in developmental syndromes. Search for i) large deletions and duplications of CNCs using aCGH in 1500 samples with malformation syndromes, 1000 from spontaneous abortions, and 500 with X-linked mental retardation; and ii) point mutations in these samples by targeted HTS. The distinction between pathogenic and non-pathogenic variants is difficult, and we propose approaches to meet the challenge. 3. Genetic control (cis and trans eQTLs) of expression variation of CNC lincRNAs, using 200 samples.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Cognitive Robotic System for Digitalized and Networked (Automated) Insect Farms' (Automated), addressing dissemination and exploitation.

assistant: **Impact**

By 2030 over 9 billion people, along with animals raised for food or kept as companions, will need to be fed generating inconsistencies between the demand and supply of food resources and promoting food insecurity by rendering food as unavailable, unaffordable, unevenly distributed or unsafe to eat. Therefore, food security represents the big challenge of the 21st century and in that context one promising potential sustainable solution is insect farming. Edible insects are set to be approved in EU by late 2020 as novel food and insects also being a value food sources for farming animals; however research, innovation, farming protocols development and standardization, and a technology leap by robotizing and automatizing the mass rearing in insect farms is needed in order to concurrently scale the production and dramatically decrease the production costs. CoRoSect addresses the dramatic need of coupling research on bionomics and life cycle of insects intended to be used as food and feed, with new robotic tools and protocols for mechanization and automation of insect farming, which is a critical point stressed by the Technical Expert Consultation on Assessing the Potential of Insects as Food and Feed in Assuring Food Security. CoRoSect forms a novel integrated cognitive robotic ecosystems where the repetitive but also cognitively and physically demanding tasks requiring increased manual effort or continuous human supervision during the insects’ lifecycle, are replaced by automatic robotic-based procedures which will also draw upon research performed on understanding biological, technical and economic requirements of insect rearing and optimizing all involved processes. Focusing on real insect rearing problems, CoRoSect technologies will evaluated through large-scale pilots
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Mechanical Understanding of Membrane Fission in Endocytosis and Cytokinesis' (MEMFIS) under Seventh Framework.

assistant: **Objectives**

The envelope of living cell is a lipid membrane. It is rather difficult to break, to ensure cell survival when under mechanical stress. However, in many events of cell life, the membrane needs to be broken in a controlled manner. It is the case in Endocytosis, when membrane carriers budding from the plasma membrane need to be separated from the plasma membrane, in order to uptake external components needed for the cell life. This reaction is called fission. It is also the case at the final step of cell division, cytokinesis, when the connecting membrane bridge between the two daughter cells is broken in a process called abscission. Even if fission and abscission machineries have been identified and are different, the reaction by which they break membranes should be the same, but is still unknown. By using membrane physics concepts and tools, we will investigate the mechanics of these two fission machineries. As they have different dynamics (tens of seconds for fission, tens of minutes for abscission), different scales (tens of nanometers for fission, microns for abscission) and different topology (fission machinery works from outside the neck, abscission machinery works from inside the neck), we will: 1-explain how each machinery breaks membranes, 2-find essential parameters that control all membrane fission reactions. We will thus draw a mechanical framework to then understand the role of keyfactors in all membrane fission reactions of cells.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'GRid ASsiSting modular HydrOgen Pem PowER plant' under Horizon 2020.

assistant: **Concept**

The GRASSHOPPER project aims to create a next-generation MW-size Fuel Cell Power Plant unit (FCPP), which is more cost-effective and flexible in power output, accomplishing an estimated CAPEX below 1500 EUR/kWe at a yearly production rate of 25 MWe.Large MW size PEM FCPP have been demonstrated, such as in the DEMCOPEM-2MW project, however at too high Capex level and without dynamic operation features for grid support. Grasshopper tackles these issues enabling a controlled, renewables-based energy infrastructure.The power plant will be demonstrated in the field as 100 kW sub-module pilot plant, implementing newly developed stacks, MEA’s and BoP system components, combining benefits of coherent design integration.Cost and technical optimisation will be achieved with improvements targeting MEAs (increasing current density, active area, reducing material costs incl. Pt loading), stack design (increasing stack size, power density and operating pressures, while streamlining manufacturability) and overall system balance of plant (modular design, simplified header and manifolds for gas distribution, high efficiency PV inverters, using off-the-shelf equipment where possible).This unit will be operated continuously for 8 months in industrially-relevant environment for engaging grid support modulation as part of an established on-site Demand Side Management (DSM) programme.This consortium unites component suppliers (JMFC, NFCT), research institutions (ZBT, Polimi) and integrators (AI, INEA) who will partner with existing energy market stakeholders (DSO, TSO) and EU smart grid projects committed to participate as advisory board members. This collaboration maximises the business case value proposition, by ensuring the delivered technology will respond to grid services’ requirements
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Chromatic homotopy theory of spaces' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Many current developments in stable homotopy theory are guided by the ‘chromatic perspective’. One decomposes a spectrum into its monochromatic pieces, each of which is a localization corresponding to one of the prime fields of higher algebra (the Morava K-theories, generalizing the prime fields Q and F_p of ordinary algebra). The goal of this proposal is to study the chromatic decomposition of spaces, as opposed to that of spectra. I will establish structural results for the category of all monochromatic spaces ‘of a given color’ and study the assembly question: how to put the pieces back together to retrieve information about the original space? The techniques are informed by my recent results relating monochromatic spaces to spectral Lie algebras, which generalize Quillen’s rational homotopy theory to all the other relevant chromatic localizations of homotopy theory.   More precisely, this research has the following goals. 1. Develop the structure theory of spectral Lie algebras and apply it to monochromatic spaces. This includes understanding Koszul duality between spectral Lie algebras and commutative ring spectra, with applications to a conjecture of Francis-Gaitsgory, and decomposition results for spectral Lie algebras, with applications to torsion exponents of homotopy groups, building on classical work of Cohen-Moore-Neisendorfer. 2. Develop a theory of transchromatic spectral Lie algebras, explaining how the different monochromatic pieces of homotopy theory interact. This connects to my previous work on the Goodwillie tower of homotopy theory and Tate coalgebras.


**Keywords:** MSC2010: 55Pxx Homotopy theory, 55P43 Spectra with additional structure, 55Q51 $v_n$-periodicity