RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Advanced Strategies for Development of Sustainable Semiconductors for Scalable Solar Cell Applications' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

SOLARUP directly addresses the ever louder call for sustainable energy production. The proposed solar energy conversion technology will reduce dependence on critical raw materials and overcome efficiency thresholds to unlock the future of flexible photovoltaic (PV) solar cells for mass deployment in smart buildings, soft robotics, wearable electronics, and other consumer products. Our main innovations lie in nanoengineering zinc phosphide (Zn3P2) for use as an earth-abundant direct bandgap semiconductor absorber, and combined with a novel device architecture we target cell efficiency enhancements of up to 15%. Advanced manufacturing techniques such as nanoimprinting and metal-organic vapour-phase epitaxy will be explored to open industrially scalable routes to synthesise high quality Zn3P2 films. Moreover, our approach will allow reuse of the growth substrate, making sustainability another core element of SOLARUP’s radical vision. Optimisation of both the absorber structure and device  architecture will be achieved through a holistic interplay of first-principles calculations and atomic scale structural and electronic characterisation. The main outcome of SOLARUP will be the demonstration of an ultrathin-film PV technology that is scalable, cost-effective, and environmentally sustainable, complete with a comprehensive life cycle analysis. In this sense our aim is to feed and inspire the development of Zn3P2-based solar cells towards a market ready technology. The project consortium unites six European teams with complementary expertise at the forefront of Zn3P2 research, device architecture, and life cycle analysis, who will approach the ambitious challenges from a flexible and interdisciplinary perspective. SOLARUP has clear potential to make science-based contribution
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Upgrading the capacities for research in translational medicine at the Faculty of Medicine University of Rijeka' (TRANSMEDRI).

assistant: **Innovation**

One of the major impediments for development of the biomedical research at the University of Rijeka has been the lack of a competitive research environment. Perhaps this is because many universities in this region retain remnants of the old socialist approach to medical education and research. Because of the limited internal resources, most of the training of the young investigators has been accomplished in the laboratories of Western countries. Although this tradition has proven to be beneficial, it has led to loss of promising scientists to faculty positions and slowed the development of a modern biomedical research. Furthermore, translational research has not been a traditional area of research in Croatia. Correction of these roadblocks can be accomplished by upgrading the research capacity and by expanding the cooperation between scientists from Croatia and those in the EU. Such an approach has already been successfully applied in several instances and is continuing to propel an increase in the research capacity at the University of Rijeka. However, it is of great importance to stress that the expansion of clinical research activities is still lagging behind basic research. The Faculty of Medicine (MEDRI) has already well-developed programs in life sciences, a respectable infrastructure, and ongoing international collaborations. The following steps in research capacity building are to further strengthen the collaboration between investigators at MEDRI and the EU countries, organize and develop formal training programmes for investigators and implement an efficient program of research capacity building with emphasis on the translational medicine in cancer and infectious diseases. Thus, several activities are proposed to synchronize training of researchers with effort
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'A research resource for investigations of post Chernobyl thyroid ca rcinoma' (1994-1998) under Fourth Framework.

assistant: **Objectives**

This application is for an internationally supported collaborative research resource for the many groups working on the problems of childhood thyroid cancer wich has followed the Chernobyl accident. It is designed to promote collaboration and avoid competition in the use of limited and very valuable resources. The three main groups involved in funding collaborative studies with the three states exposed to high levels of fallout (Belarus, Ukraine and Russian Federation) are the EC, NIH (US) and Sasakawa Foundation (Japan). The leading research groups in each organisation agree that a collaborative approach to the problem is required and have agreed to cooperate in its implementation.Approaches to the main NIS centres involved have indicated that they also are happy to cooperate. Currently different small portions of tissue are made available to different groups without adequate information, with the possibility of overlapping series being unknowingly published and of different diagnoses being made on different small portions of tissue from the same gland. The basis of the project is a collaborative approach to the collection of the tissue from cases of thyroid cancer in the areas around Chernobyl with simultaneous collection of blood samples and basic clinical information. The diagnostic needs of the patient will come first but the other tissues will then be carefully dealt with, samples frozen and the blood separated and frozen. The three major international organisations will nominate pathologists to participate in a regular meeting with pathologists from the NIS states to review all slides from the newly operated cases and provide an agreed diagnosis for the other studies being supported (molecular biological epidemiological etc.). The tissues and blood will be made a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Defining the transport pathway of the receptor-mediated sorting of lysosomal enzymes by correlative live-cell imaging and electron microscopy' (MURMAR2004), addressing dissemination and exploitation.

assistant: **Impact**

ABSTRACT An important function of the cell is the lysosomal degradation of proteins that are coming from within the cell or from the extra cellular environment. This function requires proteolytic enzymes that are present in the lysosomes. Upon synthesis, carbohydrate moieties (including mannose 6-phosphate) are attached to these enzymes, followed by a targeting step involving the intracellular transport from the trans-Golgi network to the lysosome. This transport step is mediated by the mannose 6-phosphate receptor (MPR). Immunofluorescence microscopy has suggested that the intermediate transport elements that carry the MPR/enzyme complex from the trans-Golgi network to an endosomal compartment may consist of tubules.My aim is to determine whether the MPR is indeed transported in tubules (rather than vesicles) using a recently developed correlative live-cell imaging and electron microscopy technique which capitalizes the advantages of both forms of microscopy: protein movement and morphological analysis at the ultra-structural level. Moreover, the transport elements will be further characterized by immuno-labelling them for proteins that are of particular interest, such as adaptor proteins and molecular motor proteins. For the proteins that will be found on the tubules their role in transport element dynamics will be analysed in further detail by interference studies.Using the same correlative technique together with markers specific for the distinct endosomal compartments, the endosomal compartment with which t he transport elements fuse will be identified. Identification and characterization of the MPR containing transport elements using the correlative technique will unequivocally increase our insight in the cell's capability to move membrane proteins around in a hig
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Rational Reactor Design for Enhanced Efficiency in the European Speciality Chemicals Industry' (RRD4E2), addressing dissemination and exploitation.

assistant: **Impact**

This project aims at a significant increase in the ecological and economic efficiency of today’s chemical processes by means of rational reactor design. Increasing economic pressure of European speciality chemicals producers from competitors of emerging economies requires the implementation of the latest progress in model-based reactor design and optimization into industrial practice. For this, the proposed project entangles a leading European speciality chemicals producer, LONZA, Switzerland, with a prime research site in Chemical Reaction Engineering and Reactor Design, FAU Erlangen, Germany.Current industrial production processes for speciality chemicals are commonly improved incrementally in an iterative trial-and-error approach. In order to pave the way for real breakthroughs in chemical reactor technology, a novel model-based design approach is required, which enables the design of innovative tailor-made reactors. As examples of high industrial relevance, three processes from LONZA are chosen for a thorough evaluation and optimization.Based on fundamental thermodynamic and kinetic data, the ESRs will apply a rigorous optimization strategy to define the optimal reaction conditions and to derive the best suited reactor design for each of the selected processes. Innovative additive manufacturing techniques such as Selective Electron Beam Melting enable the manufacturing of the reactor components, even with complex geometries. The identified reactor concepts are then experimentally evaluated and optimized at the laboratory scale in order to demonstrate the optimization potential for the application on the industrial level.With the optimized processes and the methods and tools at hand the European speciality chemicals industry is strengthened and excellently prepared f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'How Neutron Star Mergers make Heavy Elements' to be submitted under Horizon Europe.

assistant: **Abstract**

The incredible density, gravity, and electromagnetic field strengths of neutron stars (NS) make them laboratories for physics under extreme conditions. But probing these exotic objects is difficult. With the 2017 gravitational wave detection of a NS-NS merger, the landscape changed, and we can now get high-quality spectra of the decompressed neutron-rich matter emerging from the collision. This is a new transient astrophysical phenomenon called a 'kilonova'. Kilonovae are a potential treasure trove of information on some of the biggest open questions in physics: understanding the nuclear and astrophysical pathways that created half of all the heavy elements (Z > 30) in the universe, and the physics of very hot and extremely dense matter. For this reason, they are considered a scientific priority and kilonova science is the target of several large new and upgraded facilities. But kilonovae are challenging: the phenomenon is short-lived, requiring rapid follow-up with large telescopes, the outflow is heavy element-dominated making it extremely demanding to model, and the merger itself covers a huge dynamic range and involves complex nuclear physics. To interpret the spectra we require new atomic data, which does not yet exist for most of the heavy elements. To tackle these challenges, HEAVYMETAL assembles experts in astrophysical observations, hydrodynamical merger simulation, numerical radiative transfer, and laboratory heavy element spectroscopy and atomic structure calculation. With this team we will be able to determine the structures and overall geometries of the merger outflow, the elemental abundances, and their stratification within the ejecta. By the full exploitation of kilonovae we will trace the nucleosynthesis pathways in NS mergers, and provide important ins
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Microdata methods and practice' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Microdata, the survey data recording the economic and social behaviour of individuals, firms and other decision making agents, and the environment in which they exist, is an essential tool for the understanding of economic and social interactions, and the design of government policy. Many important questions about the behaviour of people, households, firms and institutions can only be addressed using microdata. Analysis of microdata improves understanding of the dynamics of individual behaviour, of the variation in the experience and responses of individuals and gives insight into the distributional impact of policy interventions.The last ten years has seen a rapid growth in the questions posed of these types of data, their availability, and the computing technology available to process them and in the research tools available for their analysis. Much of the recent rapid development of analytic methods has taken place in the United States although European researchers have made significant contributions. The Network aims to keep European researchers contributing at the expanding methodological frontier of this subject and to facilitate the take up of these methods by applied researchers in Europe. The overall objective of the proposed Research and Training Network on Microdata Methods and Practice is to conduct and stimulate research on, and provide training in microdata research methods and practice, disseminate the results of this research, and provide a repository of information on microdata methods and practice for new and established users in Europe and the world.The Network will develop and evaluate microdata research tools and apply them in the context of substantive social science research questions. It will provide training to researchers through course s, work
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Molecular Spin Clusters for Quantum Information Processing' in the context of a Seventh Framework call.

assistant: **Objectives**

Molecular spin clusters are prototypical systems exhibiting coherent dynamics of the electronic spin. The pattern of the lowest lying spin states is well defined and controlled at the synthetic level. The chemical bottom up approach used for the synthesis of molecules also allows to reduce intrinsic sources of decoherence and to build links between clusters, thus creating entanglement of spin states. Molecular spin clusters can be deposited at surfaces forming scalable networks. Different molecules and ligands may be combined to exploit different functionalities, the latter being defined at molecular level. These facts provide extraordinary motivation to attempt manipulation of spins and qubit encoding in these nanometer-sized molecular processors that, in turns, can be taken as test bench for the development of novel quantum algorithms.With MolSpinQIP we intend to  prove the validity of molecular spin clusters as building blocks for scalable quantum-information architectures. The project will therefore focus on the engineering of new molecules, the design of suitable computational schemes and further experiments aiming at provide compelling evidences on the manipulation of molecular spins. To achieve its goals, MolSpinQIP brings together  seven academic world-leading teams from five European countries, chosen because of their high scientific quality and track record of successful collaboration. The competencies of the team range from chemistry to experimental and theoretical physics.The goal of implementing quantum information processes is certainly ambitious but molecular spin clusters have a great potential both as a self-standing quantum device and as components of hybrid architectures. We also expect important fall out in testing novel synthetic routes to fabricate
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'PoxviRus cOnTrolled EmergenCy using Therapeutics and Innovative VaccinEs' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Recent Monkeypox (mpox) outbreaks have caught once again the world unprepared. Low-middle income countries are currently most affected by mpox, however cases keep being reported worldwide. The continues circulation of mpox can rapidly burst in a global crisis that can set-back our world into chaos, reminiscing the recent pandemic. Lack of effective and affordable medical interventions urges the need to develop innovative countermeasures against orthopoxviruses. Recent technologies and methodological advancements allow to develop vaccines and monoclonal antibodies (mAbs) in record time, and their use can be vital to stop current and future orthopoxvirus-related threats. Here we propose to discover and develop mAbs against mpox and other orthopoxviruses. These reagents will be crucial to identify and design novel protective antigens to develop innovative vaccines. We will isolate, through an antigen-agnostic approach, mAbs from mpox infected or vaccinated individuals to build a panel of neutralizing mAbs (nAbs) able to recognize orthopoxviruses shared and protective epitopes. Generative artificial intelligence will be systemically integrated in our workflow to identify antigens targeted by discovered nAbs at unprecedented speed. Data-augmentation and iterative deep-learning models will be used to in silico design new vaccine immunogens which can be produced as recombinant proteins or mRNA, or loaded on nanoparticles. This approach will provide broadly nAbs and effective vaccines designed to protect from mpox and other orthopoxviruses. If successful, the approach herein proposed will fuel the field of vaccinology allowing unprecedent speed for antigen discovery and vaccine development. This approach could be translated to all pathogens for which no cure or prevention are a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Photoacoustic imaging and artificial intelligence-based theranostic approach for cancer' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Health programs crave for diagnostic imaging and eradication of chemoresistant neoplastic lesions smaller than 1 mm of size. PHIRE, based on the outcomes from EDIT (FET-OPEN-RIA, GA#801126), aims at bringing closer to market a novel high-resolution theranostic medical device effective in the clinical applications for lesions <1 mm, ready for application in human bladder cancer and effective both in male and female patients.The PHIRE solution will be developed using swine model and will include:- an add-on module for pre-existing off-the shelf photoacoustic device allowing to perform photoacoustic imaging of hollow organs located deeper in human body, designed to be used in combination with - an artificial intelligence-assisted prediction map for the image-guided gold nanorods assisted photo-thermal therapy,- a large-scale synthesis of urine-stable gold nanorods for clinical use. The adoption for clinical applications of this new device will reduce the frequency of the bladder tumor relapse and the number of patients with relapsing tumor, with a drastic positive impact on the quality of life of patients while reducing the social cost of the management of patients. Furthermore, PHIRE’s results will open up the way for the deployment of theranostic application against lesions <1 mm in other hollow human organs.PHIRE innovative solutions will also be applicable to other markets, such as that of photoacoustic and diagnostic imaging, gold nanoparticles, cystoscopy and medical software.""


**Keywords:** High-resolution theranostic approach; artificial intelligence; cystoscope; gold nanorods; good manufacturing practices; photothermal therapy; bladder cancer.