RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Structure, function and molecular pharmacology of neurotransmitter receptors-polyamines as key tools and potent neuroprotectants' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

- To develop novel, potent and specific analogues of polyamine amides and polymethylene tetraamines containing aromatic units.- To study the interactions of polyamine amides and polymethylene tetraamines with native and cloned acetylcholine and glutamate receptors- To develop polyamines and polymethylene tetraamines as neuroprotectants.The project is designed to develop novel, potent analogues of natural neuroactive amines occurring in wasp and spider toxins; these polyamine amides and polymethylene tetra amines containing aromatic groups are of interest as tools for investigating specific neuroreceptors in the central and peripheral nervous system. More importantly, the compounds are potential neuroprotectants for exploitation by the EU pharmaceutical industry. The project will involve close collaboration between medicinal chemists, pharmacologists, molecular biologists, neuropathologists and biochemists to achieve a set of carefully designed goals. The studies will target nicotinic and muscarinic acetylcholine receptors and ionotropic glutamate receptors, and will employ native receptors, in vivo and in vitro, as well as cloned receptors. Antagonism of these receptors by polyamine amides and polymethylene tetraamines will be optimised using biological evaluation as well as physico-chemical and structural characteristics of the compounds. The latter will involve NMR spectroscopy and molecular modelling. The biological optimisation will include receptor binding characteristics and electrophysiology.Binding domains for the polyamines will be elucidated using photoaffinity labelling, receptor isolation and purification and peptide sequencing. The potential binding domains will be evaluated using cloned receptors mutated at single or multiple sites. A strong synthetic chem
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Advancing percutaneous heart valve repair in children through the development of new cardiac imaging strategies' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The development of non-surgical methods for the treatment of heart valve disease in children as well as in adults has recently become a reality. The increased use of these methods would improve patient comfort, avoid prolonged hospital care and stay, and enable patients to return to normal daily activities in a shorter time, ultimately reducing healthcare costs. We currently have the largest worldwide experience of implanting percutaneous valves into the pulmonary position, and have safely performed over 200 cases. Magnetic resonance (MR) imaging has played a crucial role in the success of this programme by accurately defining the anatomy of the implantation site for improved patient selection and by demonstrating the technical and physiological success of the treatment. However, at present only a limited number of patients can benefit from this procedure due to variations in individual patient anatomy and loading conditions. The aim of this application is to use the past experience gained with MR imaging in the pulmonary position, along with similar and new methodologies, to enable device implantation in all patients' right and left ventricular outflow tracts. This will be achieved by using patient imaging data to systematically categorise implantation site morphology and dynamics and to develop models that will accurately predict modes of device failure. The imaging modality that can be best used to carry out these assessments and is most suited to aid device design will be established. Furthermore, imaging methods that will assist in the deployment of devices into complex cardiac morphologies will be developed. Overall these approaches will help us fully understand the implantation site, improve patient selection for safe device deployment, and create new methodologi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'The Philosophy of Experiential Artifacts'.

assistant: **Objectives**

Ancient Greeks used one word, techne, to designate both technical and artistic practices. It is only in modern times that art gained autonomy, becoming the object of one philosophical discipline: aesthetics. However, the emergence of mass media, and then of digital media, has brought art close to technology, challenging its autonomy. In this situation, some basic philosophical questions about art regain centrality: Why art? What is art for? What is the role of art in a technological society like ours? The traditional answer stresses the uniqueness of art, pointing to the essential difference between artworks and technical artifacts. The increasing interchange between art and technology, however, encourages us to question this statement, pursuing an alternative strategy. The hypothesis is that artworks belong to a technical kind which has been overlooked so far: the kind of experiential artifacts whose function consists in triggering experiences. Art is severed from technology only if one focuses on artifacts such as drills or lathes whose function consists in producing concrete effects. Yet, once experiential artifacts have been recognized, one can fruitfully connect art to technology, rethinking forms of art as techniques for generating different types of experiences. The PEA project launches the philosophy of experiential artifacts as a new area of inquiry in which the relationship between art and technology can be properly theorized, thereby offering a new conceptual toolbox for historical and empirical research. This will be done through a fourfold methodology in which aesthetics and the philosophy of mind analyze the experiences that experiential artifacts are meant to trigger, while metaphysics and the philosophy of technology investigate the structure in virtue o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Dark signaling mechanisms involved in the regulation of the developmental switch from dark to light growth in Arabidopsis seedlings'.

assistant: **Concept**

One of the most dramatic changes in plant growth and development is the transition from life in the underground darkness after germination of the buried seed, to life in sunlight when the seedling reaches the soil surface. In Arabidopsis, seedlings in the dark have long hypocotyls, closed unexpanded cotyledons protected by an apical hook, and lack pigmentation.Upon transition to light, seedlings switch their developmental program to adjust accordingly: the hypocotyl slows down elongation, the apical hook unfolds, cotyledons separate and expand, and chloroplasts develop and accumulate chlorophyll. Recent studies have shown that the phytochrome (phy) A and phyB photoreceptors, and the phy-interacting bHLH transcription factors PIF1 and PIF3 are involved in this process, together with the E3 ubiquitin ligase COP1. Despite increasing progress, the mechanisms operating in this dark-to-light developmental switch are still largely unknown.The main objective of this proposal is to identify the regulatory mechanisms involved. Previous results have revealed the importance of the dark period in the regulation of this process. We propose to examine the protein and gene expression profiles during dark development in Arabidopsis seedlings to identify differentially regulated factors with a role in the dark-to-light switch.The specific objectives are:- identification of factors differentially expressed in dark-grown seedlings using a novel proteomics approach and through the analysis of genomic profiles; and- characterization of the role of the new identified factors in the dark-to-light switch in development using reverse genetics and molecular approaches.This proposal fulfils the objectives of the IRG Programme to contribute to European research and transfer the knowledge acquired b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Contribution of Land water stOrage to Sea-level Rise' to be submitted under Horizon 2020.

assistant: **Abstract**

Sea-level rise is one of the most dreadful consequences of future climate change. To estimate the associated risk and prepare ourselves better for its implications, we need to identify the spatiotemporal characteristics of the contributors to sea-level change. Out of all the contributors, land water storage change is the most debated one because studies so far do not even agree on its sign. In the framework of CLOSeR (Contribution of Land water stOrage to Sea-level Rise), I will estimate the spatiotemporal characteristic of contribution from land water storage to sea-level rise between 2002 and 2020, in a robust statistical framework called BHM (Bayesian Hierarchical Modelling) with the help of: 1) multi-mission satellite altimetry data over oceans 2) a new data-driven leakage corrected GRACE product 3) steric information from ARGO floats and 4) a novel data-driven GIA model. Within this two-year fellowship, hosted at University of Bristol, supervised by Prof. J. L. Bamber, I will develop a data-driven leakage corrected GRACE product for global applications, develop a BHM to solve for land water storage contribution while closing the sea-level budget, and identify the regions that contribute significantly to sea-level rise. The approach is unique, global in scale, and will address a multi-disciplinary problem comprehensively. The proposed action will complement the goals of GlobalMass project at University of Bristol and will go beyond. CLOSeR will produce significant advances in understanding the role of land water storage in contemporary sea-level change that will help us better predict the future. For the first time, we will produce spatial and temporal hot-spots of land water storage contribution to sea-level rise using a cutting edge statistical tool for signal sep
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'The Effects of Air Pollution and Physical Activity on Respiratory Health in Children in the Context of Urbanization'.

assistant: **Concept**

Urbanization has changed the land-use in Europe and the majority of the world. Over 80% of Europeans, who are expected to live in urban neighbourhoods by 2030, are at risk of developing chronic respiratory disease (CRD) due to the chronic exposure to increased levels of air pollution, that is characteristic for urban and peri-urban areas. Increased car traffic due to high population and building densities in cities have been associated with poor air quality. Research on how the continued urbanization and the built environment affect human health is emerging. To date, very little is known about how the built environment affects respiratory health in children directly, or indirectly by influencing health behaviours such as physical activity. Childhood is a period of growth and development, which makes children particularly vulnerable to changing environments. Because the respiratory system and the lungs act as the first organ of contact with air pollutants, the health effects of air pollution exposure need to be studied in combination with physical activity. Physical activity increases the breathing rate and the depth of breaths taken in, which facilitates pollutants to reach areas deep in the bronchial tree at higher concentrations, where they can cause damage locally, or be absorbed into the blood stream, and impact regulatory processes systemically. The purpose of this project is to analyze how the built environment affects the combined exposure to air pollution and physical activity with respect to children's respiratory health pre- and postnatally using an exposome approach. We will use data from the Human Early-Life Exposure (HELIX) project, including 1301 mother-child pairs from 6 longitudinal cohort studies across Europe. This research is important, because we wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'HARBOR. Humanitarianism and Refugees at the Border: A Transnational Feminist Analysis of Nonprofit Organizations'.

assistant: **Innovation**

HARBOR—Humanitarianism and Refugees at the Border—departs from the idea that humanitarianism is a neutral and timeless ideology, and instead turns a critical eye towards this sector to understand the ways in which nonprofit organizations become complicit with the neoliberal order—through reinforcing certain ideals of citizenship and sovereignty, occupying spaces that are destined for public institutions, and influencing refugees’ decision-making processes—and their possibilities for resistance. This feminist transnational comparison project expands my previous research in the refugee nonprofit sector at the US-Mexico border by including the two other most sought-after destinations in the world for refugees: Australia and Europe. Its aim is to make connections between nonprofit local practices and global dynamics to draw broader conclusions about the role nonprofit organizations play within refugee management. Through a combination of a transnational feminist lens and a Foucauldian framework, as well as ethnographic, participant observation and interview methods, HARBOR will reconstruct the role that humanitarian organizations play in the current refugee regime. In so doing, this project works at the connections between the academic, humanitarian, and policy-making sectors. In order to achieve my research objectives, I will be based at the University of Queensland (UQ) in Brisbane Australia where I will be trained in Global Governance and feminist political theory under the supervision of Dr. Hoffstaedter. Upon my return to my European host institution, CSIC, I will bring my new skills and engage in theory-building that challenges the idea of borders as protection with my mentor Professor Velasco at the Humanities Research Center.


**Keywords:** Refugees, transnational
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Mini Factories for 3D printing of Large Industrial Composite Structures' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The increasing global demand for renewable energy utilization sets a positive growth scenario for the wind energy sector. Indeed, it is predicted that the global wind power capacity at 318 GW at the end of 2013, to reach 618 GW by the end of 2020. However, despite the growth potential, the wind energy sector faces several challenges that might endanger its long term sustainability. These challenges refer mainly to the industry competitiveness, which is increasingly affected by the price reduction of other energy alternatives, and because the most profitable (windiest) places are already occupied, the available free space is less profitable in terms of bulk energy generation, as well as a progressive reduction in government level subsidies (example in UK and Spain). This results in a strong price sensitivity for the wind energy sector, for which the only alternative goes through a significant reduction of bulk power costs. Considering that the price of wind turbines accounts for more than 80% of the total costs of a wind farm (2M-4M€/turbine), it is clear that reducing wind turbines prices is the only meaningful solution for the long term sustainability of the sector. 3D-COMPETE will provide the wind energy sector with a low cost solution for manufacturing the complex and heavy structural parts of wind blades. The proposed innovation is the use of an additive manufacturing process, automated fibre placement (AFP), which will enable the automation of the process. Our solution will reduce the manufacturing costs of these components by 40% (from 4,000€/ton down to 2,400€/ton). As for understanding the business opportunity, 3D-COMPETE solution will bring our customer (wind blade manufacturers) savings that can range €3.5M/year (for smaller clients that produce ~400 wind blad
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Linking substrate consumption to consumer identity in carbon-cycling microbes inhabiting anoxic marine sediments' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Much of the organic matter produced on land and in aquatic systems is eventually deposited at the seafloor, making marine sediments the largest organic carbon sink on Earth. Predominantly, this organic matter is either remineralized to CO2 via biological activity or preserved over geologic time scales. A substantial fraction of remineralization is carried out by microbes that live below the sediment surface in the absence of O2. To date, these anaerobic microbes remain largely uncharacterized. A detailed knowledge of these microbes and their activities is, however, essential to understanding the role of marine sediments in the global carbon cycle and in regulating ocean chemistry, atmospheric gas composition, and ultimately Earth’s climate. In the following project, I propose to investigate the fate of several common low-molecular weight carbon compounds (formate, acetate, lactate, methanol, methyl chloride) in anaerobic marine sediments from three different locations, Aarhus Bay off of Jutland (Denmark), the Guaymas Basin off of Baja California (Mexico), and the Bering Sea off of Alaska (USA). By inoculating sediments with media containing single substrates or mixtures of substrates, I will select for growth of microbes specialized to use single substrates and ones adapted to use several substrates simultaneously. The three metabolic groups I will select for are sulfate reducers, methanogens, and acetogens, all three of which are key players in organic matter remineralization in anoxic marine sediments. Substrate consumption will be linked to consumer identity by supplying substrates in 13C-labeled form and by monitoring substrate uptake and incorporation into biomass via stable-isotope probing (SIP). This project would allow me to after 12 years abroad transfer state-
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Superstition, Material Religion and Hıdrellez in Turkey', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

This project will investigate the history of Turkey in terms of religion, rather than Islam, to understand the roots of the normative understanding of religiosity as Sunni-Islamic. The aim is to comprehend the “Western” influence on religion and Islam in Turkey and to illuminate the history of material forms of religiosity by focusing on Hıdrellez, a religious practice that was, and still is, celebrated in a convivial manner by people of different ethnic and religious backgrounds. While recent critical approaches in global religious history and material religion aim to overcome any Eurocentrism that still persists in religious studies, the case of Turkey still remains largely unexplored. Situated at the intersection of religious studies and history, this project will break new ground by bringing together a postcolonial history of “superstition” with the historical analysis of “material religion”, and will advance global debates on how religion is discussed today through its critique of essentialist definitions of Muslim majority nations. The research objectives are: (1) to examine the role of “superstition” in the categorisation of Islam during the 1950s as a form of global entanglement between Turkey and the “West”, (2) to investigate the research on the history of religions and “superstitions” as a form of entanglement between Turkey and Germany, (3) to empirically analyse the history of the diversity of religious life by focusing on Hıdrellez, (4) to analyse the transformation of Hıdrellez from a religious practice to Intangible Cultural Heritage. SUPERSTITIOUS will generate international collaborations and foster vibrant cooperation between scientific communities, civil society representatives and citizens. In the early years of the second centenary of the Republic