RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Biofuel Cells : From fundamentals to applications of bioelectrochemistry' (BIOENERGY).

assistant: **Innovation**

The proposed ITN BIOENERGY deals with the understanding of experimental limits and fundamental principles for exploiting and developing electro-conducting nanoarchitectures to assemble highly efficient bioelectrocatalytic structures as a basis for efficient and stable biofuel cells. Based on that fundamental understanding, the main technological objective of BIOENERGY is to develop efficient and stable biofuel cells including potentially implantable biodevices. Individual elements like electrodes, enzymes and mediators will be developed, integrated into each other and finally assembled to bio fuel cells. ESR and ER will be work on the all tasks of this scientific chain being therefore trained in the fundamentals of bioelectrochemistry, modern experimental methods in bioelectrochemistry and applications of bioelectrochemistry. Training of the fellows will take place at the host institute, via secondments, workshops, summer schools and joint measurement campaigns. The scientific training will be completed by training of complementary skill with respect management, fund raising and scientific communication.The consortium consists of the leading scientists in bioelectrochemistry in Europe and is supported by several private partners working in the field. It is expected that BIOENERGY will improve the availability of a highly skilled workforce for European industries and research, and will be the seed of innovative long-term research and education in bioelectrochemistry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Energy Storage in Molecules' under Horizon Europe.

assistant: **Concept**

ESiM will create the scientific basis for a radically new technology addressing the pressing challenges of scalable clean energy storage. The ESiM strategy is to use the conformational degrees of freedom of organic molecules, and to create dense molecular arrays of scalable dimensions on a surface to avoid the limits of battery technology based on ions flow and on environmentally harmful substances. ESiM will provide the proof of principle that storing energy in molecules is feasible, constructing laboratory devices and validating the scientific and technological basis for novel energy storage devices. ESiM will produce scientific and technological achievements well beyond the fields of the individual partners, involving chemistry, physics, and simulation tools. The added value of our interdisciplinary approach will enable the development of methods and materials for an efficient storage of energy in specific degrees of freedom of organic molecules on a supporting surface, ultimately leading to an environmentally friendly, recyclable way of producing, storing, and using energy. Molecules will be designed and synthesized to first capture a possible deviation from the micro-reversibility principle and demonstrate energy pumping and storing in a few specific intramolecular mechanical degrees of freedom. Then, 2D molecular layers will be developed to efficiently store this energy using electric fields and inelastic electrons as a second energy source. As a proof of principle, ESiM will produce a device based on a bimetallic cantilever to store and release energy from the active molecules. ESiM will maintain close contact with industry via regular meetings (ESiM-Industry days) involving nanotechnology startups, energy providers and high-tech SMEs, to favour exchange and syne
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Symbolic techniques for circuit optimisation' in the context of a Sixth Framework call.

assistant: **Objectives**

During the last decade, advances made in fabrication technology and photolithography have fostered the step from micro- to nano-electronics allowing integrated circuits to be produced on an ULSI basis. This has greatly increased the complexity of state-of-the-art integrated circuits whose design is even more targeted towards system-on-chip solutions. In this context, the role of CAD techniques for circuit analysis and optimization became essential to obtain solutions that satisfy the requested performance with the minimum time effort (i.e., minimizing the time-to-market).The research topic of this project concerns the development of an integrated symbolic optimization environment that merges the capabilities of state-of-the-art symbolic analysis techniques and optimization algorithms. The motivation for applying symbolic techniques, instead of traditional numerical analysis, to the field of circuit design is twofold: on one hand, to allow for faster performance evaluation of even complex circuits; on the other hand, to gain insight into circuit behaviour through inspection of simple analytical expressions.Special regard will be given to the investigation of nonlinear symbolic techniques for single- and multi-objective optimization of real-life circuits of industrial complexity. The inter-sectorial character of the project is guaranteed by the fact that involved partners operate in two distinct fields, i.e. microelectronics and applied mathematics, whose mixture will generate knowledge, innovation, and added-value for both of them.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Anti-counterfeit foil for security packaging' (ACfoil).

assistant: **Concept**

ProblemMore than one million people die each year from counterfeit medicines. 700,000 people in Africa die each year as victims of counterfeit malaria or tuberculosis drugs. The pain is not just financial – more than 200,000 jobs are lost due to counterfeiting in the US and Europe alone.Solution – the innovationAuthenticity can be guaranteed by adding holograms to each individual box or bottle of medicine, but costs have so far been prohibitive. Inmold has found a way to mass-produce such holograms at least 100 times faster and 10 to 10,000 times cheaper than current state-of-the-art, and as a small and simple expansion of packaging equipment already commercially available. Inmold’s innovation can be both retrofitted and delivered with new equipment. The projectInmold has taken out four patents on the innovation, demonstrated a prototype with success with respect to parameters such as price and production speed, and established that there is an interesting market opportunity. However, since the pharma industry is quite conservative it is necessary to show customers customized designs as well as to get feedback from the market on sales and price models, implementation strategies and product features, which is the purpose of the project.Business modelInmold and Danapak has formed a collaboration where Inmold supplies production equipment and consultancy to Danapak using a licensing model with profit sharing. Danapak already supplies packaging equipment to the pharma industry and, hence, is a perfect partner for Inmold, who cannot approach the pharma market alone.Customers and marketThe pharma market is very large, yielding a significant packaging market volume of at least €700m. Danapak has a market penetration of 20-35%, depending on segment. Glaxo Smith Kline, Johnson &
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project '5G HEalth AquacultuRe and Transport validation trials' (5G-HEART) under Horizon 2020.

assistant: **Objectives**

Healthcare, transport and food verticals are hugely important in Europe, in terms of jobs, size (collectively surpassing €3Trillion) and export trade. Moreover, they are vital from a social perspective, for better patient outcomes, safer transportation and safer and more sustainable food production. 5G is important for these verticals, in terms of improvements for utility, efficient processes, safety among others.5G-HEART (validation trials) will focus on these vital vertical use-cases of healthcare, transport and aquaculture. In the health area, 5G-HEART will validate pillcams for automatic detection in screening of colon cancer and vital-sign patches with advanced geo-localization as well as 5G AR/VR paramedic services. In the transport area, 5G-HEART will validate autonomous/assisted/remote driving and vehicle data services. Regarding food, focus will be on 5G-based transformation of aquaculture sector (worldwide importance for Norway, Greece, Ireland).The infrastructure shared by the verticals, will host important innovations: slicing as a service; resource orchestration in access/core and cloud/edge segments with live user environments. Novel applications and devices (e.g. underwater drones, car components, healthcare devices) will be devised. Trials will run on sites of 5G-Vinni (Oslo), 5Genesis (Surrey), 5G-EVE (Athens), as well as Oulu and Groningen, which will be integrated to form a powerful and sustainable platform where slice concurrency will be validated at scale.The consortium includes major vertical players, research/academic institutions and SMEs. Partners have proven know-how in 5G, vertical applications, standardisation, business modelling, prototyping, trials, demonstrations.5G-HEART KPI validation ensures improved healthcare, public safety, farm mana
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Coalition formation and distribution' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

The project I intend to undertake is divided into three parts. I . Analysis of (a) how individuals/firmslparties form coalitions; (b) how they split the surplus of cooperation. 2. Dynamic and strategic analysis of the effects of wealth distribution on optimal contracts and institutional change. Particular attention to market structures and credit markets. 3. Theoretical study on the efficiency implications of different initial distributions of commodities for trade Nash-equilibria in market games.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Hierarchical performance evaluation modelling of large information open systems' in the context of a Fourth Framework call.

assistant: **Objectives**

The objective of the project is to enable enterprises to cope with the wave of second generation client/servers by helping users to visualise and understand the way their workload would be handled by new middleware technologies. The next generation of client/server systems will inevitably be built using three-tiered architecture, where object oriented technology will be the ultimate form of self managing distribution.The project will develop a workbench to predict and analyse performance and thereby aid the sizing and the configuring of commercial systems by service suppliers, service integrators, client/server editors and customers as well. This will provide:- performance prediction of a particular configuration and workload,- the ability to analyse and display information in a way that is easy to understand and which highlights bottlenecks,- tuning assistance for an existing configuration for a particular workload.As companies deploy mission-critical applications across distributed client/server environments, performance complexity becomes a major obstacle. Today's distributed environments are not only more technologically diverse and geographically dispersed than in the past, they are also more dynamic. Managing performance across many application, system and network components in these new environments is absolutely vital to minimise the impact to the business.Modelling an information system (IS) is a complex and cost consuming task. HELIOS approach consists in offering a wide library of predefined models for main computing products (hardware, software) in a workbench. The user friendly interface of this tool and re-usability of component models allows IS designers to get a fast modelling and a cheap performance prediction.HELIOS work is built on the background of S
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Update your environment: Neural foundations of spatial updating in real and virtual space' (2002-2006), addressing dissemination and exploitation.

assistant: **Impact**

Knowing where one is relative to surrounding objects is a central feature of situational awareness and readiness to act. As we move through an environment, we must constantly update our location and orientation in order to effectively act upon external objects or to avoid getting lost. This process has been termed spatial updating, and it is of major importance in everyday life. For example, when objects go out of view or when people operate in situations that are rendered visually unreliable and impoverished, efficient behaviour crucially depends on accurate spatial updating. In sharp contrast to the wealth of behavioural studies on spatial updating, the underlying cortical system remains poorly understood. Conflicting findings in neurological patients wit h parietal lesions highlight the need for complementary methodological approaches.In addition, lesion studies do not allow to assign specific updating functions to circumscribed brain regions or to assess the dynamic interactions between participating structures. The current project will decipher the cortical network that supports spatial updating with a combination of behavioural research and neuro-imaging experiments. Highly sophisticated methodological techniques will be applied in the context of function al magnetic resonance imaging (i.e. effective connectivity) and diffusion tensor imaging (i.e. probabilistic fibre tracking).This approach will substantially extend our knowledge about how the human brain weights information from a surrounding environment in order to maintain oriented or to build up a corresponding mental representation. In addition, identifying the neural foundations of spatial updating will help to finesse current theories on environmental learning and to characterise the determinants o f inter
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'A stem cell-based approach for modelling implantation in vitro' to be submitted under Horizon 2020.

assistant: **Abstract**

The first physical contact between the embryo and the uterus is a complex and timely coordinated process, which is crucial for positive pregnancy outcome. During that process of implantation, the embryo attaches and invades to nest into the uterus. Managing embryo implantation has wide implications for public health, including treating infertility (e.g., improving IVF outcomes) and for family planning (improving contraception). However, the tiny size of the embryo and inaccessibility into the womb make implantation a true black box in developmental biology. Three technological breakthroughs, i.e., single cell sequencing, endometrial organoids and blastoid technologies, now made it possible to deeply and finely investigate implantation. Here, I aim at leveraging these technologies to create a stem cell-based platform to model the blastocyst-uterus interaction and to reveal molecular mechanisms mediating implantation. This platform will be amenable to high-throughput screening, gene editing, and live imaging, to identify the molecular regulators of implantation. If successful, this study will provide a biologically relevant, easily accessible and experimentally amenable system to perform in-depth studies with scientific and clinical impacts to understand and potentially treat conditions such as infertility, reproductive decline, develop novel contraceptive and in the long term, to develop drugs to improve reproductive health and prevent several chronic diseases.


**Keywords:** Infertility, Implantation, Endometrium, Organoid, Blastoid
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Study of the role of mast cells in the modulation of immune and inflammatory responses associated with eczema: novel genetic approaches from mouse systems and relevance to the human disease' (2007-2013) targeting Seventh Framework.

assistant: **Abstract**

The overall objective of this grant is to complement Dr. Marichal’s expertise in basic and translational Allergy and Immunology. He will therefore integrate an outstanding laboratory in this area (Pr. Stephen J. Galli’s laboratory) at Stanford University School of Medicine, a world leader in medical education, training and research. Scientifically, Dr. Marichal will acquire cutting-edge knowledge in the detailed mechanistic understanding of allergic disorders, which are increasingly recognized as a major global public health problem. Indeed, the current proposal aims to evaluate in depth the contribution of mast cells in early immune and late inflammatory responses associated with skin eczema, the most complex allergic skin disorder. To address this question, two complementary genetic approaches of mast-cell deficient mice will be used in combination with a clinically relevant mouse model of skin eczema. In addition, Dr. Marichal will learn and take advantage of the innovative tool of Gene Set Enrichment Analysis to assess to relevance of the findings to the human disease. This challenging project is possible thanks to Dr. Marichal’s previous experience, in combination with the financial and technical resources of the host laboratory, as well as the scientific and training environment that will be provided. Pr. Galli has indeed a long history of highly successful training of postdoctoral researchers. Moreover, Dr. Marichal will benefit from many training and educational programs, enabling him to gain essential skills at the level of leadership, project management and financial independency and helping him in growing as an independent researcher. Finally, it is the goal of the outgoing and return host laboratories to create a strong international collaboration and a worl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Resilient cooling towards climate change adaptation of cities and buildings' under Horizon 2020.

assistant: **Concept**

ResCool is targeting an advanced building energy simulation to consider the thermal interactions with urban microclimate under climate change scenarios, aiming at supporting the climate-resilient design of cities under growing heatwaves. The effects of heatwaves in cities are one of the most critical overlooked issues of our time. They will occur more often and last longer, increasing the likelihood of severe and irreversible impacts for people and ecosystems. The objectives of this project are the development and validation of a holistic and reliable methodology to evaluate the heat vulnerability of cities; the identification of the climate-related hazards and risks of reference urban contexts in Europe; the selection of the best available climate-resilient solutions to strengthen resilience and adaptive capacity of cities; and the development of a climate-resilient cooling action plan and a decision-support tool for the sustainable development of urban planning policies. The project’s core research is divided into five work packages (WP). WP1 develops a bottom-up evaluation workflow of urban contexts facing climate change scenarios. WP2 validates this methodology thought data collection in two representative urban case studies in the United Kingdom and Spain. WP3 evaluates the heat vulnerabilities and climate risks of representative urban contexts. WP4 carries out a parametric analysis of resilient cooling strategies to highlight the best available solutions under climate change scenarios. Finally, WP5 uses the collected results to develop a tool to support the climate-resilient pathway by policymakers and authorities. The results will derive in context-specific policy recommendations and how governments can best incentivise, govern and regulate low-carbon and effecti