RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Leveraging Artificial intelligence for Astrophysical Source parameter Estimation and Rapid electromagnetic follow-up with the future space-based Gravitational Waves Observatory' (LASERGWO).

assistant: **Concept**

The Laser Interferometer Space Antenna (LISA), a milli-Hertz gravitational wave (GW) observatory, has extraordinary scientific potential. It is expected to revolutionize multimessenger astrophysics in the mid-2030s through synergies between LISA and both space- and Earth-based electromagnetic (EM) observatories. Mergers of supermassive black hole binary systems will be primary sources for these multimessenger studies. LISA will detect GWs emitted during the pre-merger phase and pinpoint the source location, allowing EM observatories with narrow fields of view to search for potential counterparts. For this synergy to be effective, rapid alerts of sky positions and coalescence timing are crucial—not only at the moment of merger but also in the hours leading up to it, when precursor signals may occur. This raises a vital question: what strategies or technologies will ensure that EM observatories are prepared to respond in nearly real time?My project addresses this urgent need by developing a low-latency alert pipeline (LLAP). Unlike detailed astrophysical analyses, which can be adjusted post-event, the LLAP must be operational from the start of LISA’s mission to enable prompt identification, analysis, and follow-up of transient events. This pipeline will leverage deep learning algorithms to process LISA’s raw phasemeter data and generate posterior parameter distributions for binary coalescences. This novel approach bypasses standard initial data processing stages, aiming to reduce alert latency for EM observatories. Moreover, it integrates data analysis tools and hardware, as the LLAP will be validated using experimental data from a Field-Programmable Gate Array-based LISA Delay Hardware Simulation developed at AEI Hannover. This experiment simulates onboard measurement ch
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Continuous two-dimensional Stretch monitoring of fresh tissue Biopsies' (StretchBio).

assistant: **Concept**

Mechanical tension and stresses are considered key factors associated to the control of the growth and proliferation of tumoral cells and tissues. Monitoring of such stresses would help to better understand cancer progression and also to test the effectiveness of anticancer drugs aiming to restore normal tissue mechanics. However, there is no currentsystem available for monitoring the cellular mechanical properties, particularly for small tissue biopsies like those obtained with core needles.The overall goal of the StretchBio project is the design, development, fabrication and proof of application of an advanced label-free and compact nanosystem for the continuous monitoring and quantification of mechanical stresses in ex vivo fresh tissue biopsies. This nanodevice will allow testing the changes of these tissues upon their treatment with anticancer drugs for improved drug screening. The basic principle of StretchBio is a two-dimensional force sensor based on an array of nanopillars, constituting a photonic crystal, in which the bending of one or more nanopillars, caused by the mechanical forces exerted by the living tissue, will give rise to a change in the transmitted light through the photonic crystal. The design and fabrication of this compact nanosystem needs to be addressed in concomitance with liquid cell culture media, which will constitute the interpillar medium, and with the fact that the ex vivo fresh biopsy needs to be placed on top of the nanopillars.The proposed approach will be an enormous leap in the study of tissue growth and of drug screening in solid tumours whose progression is markedly contributed by tissue stiffening. This represents an innovative approach to personalized medicine, allowing the development of ad-hoc treatments.


**Keywords:** photo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Solid-phase synthesis of imprinted nanoparticles exhibiting glycan epitope recognition in glycoproteins' under Horizon 2020.

assistant: **Concept**

The present project aims at the preparation of synthetic nanoreceptors exhibiting glycan epitope recognition in glycoproteins, identified to play a critical role in cell biology and diseases. Such nanoreceptors, behaving like antibodies, may cope with the current limitations in the essential step of enrichment of specific glycan subclasses, within studies of the glycoproteome. The preparation of the receptors will proceed through solid-phase synthesis of imprinted polymer nanoparticles, with the potential to deliver entities with size, specificity and solubility characteristics comparable to antibodies. The solid-phase synthesis of NanoMIP will require the immobilization of important monosaccharides (N-acetylglucosamine, N-acetlgalactosamine, mannose), widely found in glycoproteins, onto supporting beads. Several synthetic routes will be studied for the immobilization onto silica or plastic beads . In a reactor, built as a controlled temperature glass column filled with the beads containing immobilized monosaccharide, criteriously selected polymerization or sol-gel mixtures will generate the nanoMIPs, with subsequent selection of the highest affinity particles. The optimum combinations of solid-phase/imprinting protocol will be screened from a myriad of nanoMIPs prepared in different conditions. The performance of the nanoMIPs will be ascertained by setting a competitive enrichment protocol consisting of the incubation with a mixture of N-acetylglucosamine-, N-acetylgalactosamine- and mannose-containing glyproteins and a non-glycoprotein. Sorption isotherm data will be used to derive important binding features such as capacity, binding affinity and selectivity. Patentable robust solid-phases and imprinting protocols, either in standalone or combined manner, are planned
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'New ecological BIO CERAMIC INK based on bio-solvents for ink jet printing (BIOCERAMINK)'.

assistant: **Objectives**

The goal of BIOCERAMINK project is to commercialize a new type of ceramic ink produced using solvents obtained by vegetal oil instead of solvents made of glycol ether.The BIOCERAMINK wil be derived from vegetable oils, easily available, improving even the graphics, reducing the fouling of the heads and bars of printers, eliminating clogging or the closing of the nozzles, improving and finally reducing the cost of the inks, of about 30%.In this way the quality of the products will improve and consequently quality of the prints, without increasing production costs. It should be added that the development of vegetable-based inks can solve the problem of the reduced availability of hydrocarbon-based solvents, such as glycol ether (TPnB), due to an over-production of related compounds pollutants, little used.The expected results at the end of overall innovation project will be:1. new marketable ecological products, with low content of alcohol, reduced effects of sedimentation and new range of pigments (colors);2. full range of produce prototype inks based on components renewable and capable of becoming industrial products (pre-industrial prototypes)3. full demonstration of BIOCERAMINK in industrial application pilots;In order to achieve the above mentioned innovation objectives, a feasibility study is needed:1. to carry out an extensive market analysis and validation study allowing to clearly identify and quantify main market segments, also defining main market drivers, customers desiderata and go to market strategy.2. To define an industrial development plan aiming at setting up the requirements for a pilot plant that will simulate the reproducibility of the BIOCERAMINK product at commercial scale. The technological roadmap will drive DEF in completing the BIOCERAMINK devel
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Enabling sustainable AiR MObility in URrban contexts via emergency and medical services' in the context of a Horizon 2020 call.

assistant: **Objectives**

AiRMOUR focuses on research and validating novel concepts and solutions to make urban air mobility safe, secure, quiet and green but also more accessible, faster, affordable and publicly accepted. In response to the call, AiRMOUR presents an approach that takes on one of the most critical and challenging early real life applications of UAM in Emergency Medical Services (EMS). EMS provides a versatile scenario pool that facilitates thoroughly investigating the urgent challenges at hand applying a result driven quadruple helix approach. AiRMOUR fills in the excellence gaps and drastically advances the understanding of needed near-future actions by urban communities, operators, regulators, academia and businesses. The approach and the outcomes will massively benefit the entire UAM development in EMS, but also widely within e.g. the vision of true airborne mobility genuinely supplementing traditional transport modes. AiRMOUR concept centers on thorough research of safety, regulation, user acceptance, sustainability; leveraging them into practical and real-life tangible UAM tools after TRL6 live validations. A strong consortium of research, national aviation, regional and local urban authorities, UAM operators and EMS can guide cities making sure that the impacts are replicated widely. Main outputs are UAM toolbox with a UAM GIS tool for authorities, a UAM guidebook (for cities, operators and other stakeholders) and a UAM training programme together with Eurocontrol, all tested by cities and replicators. The crucial impact of AiRMOUR will be increased UAM competence of city and regional staff and their partners in public transport, energy, innovation and funding. Participation in AiRMOUR allows hands-on testing of the UAM toolbox as well as take-up of future UAM scenarios. E
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'New environmentally friendly insulated boxes for the fishing industry.' (1998-2002).

assistant: **Innovation**

There is a great demand for high quality fresh fish in Europe . Insulated boxes are essential to maintain the quality of fresh fish. As soon as fish is caught a reduction in temperature is required and a low temperature should be kept until the fish reaches the consumer. Ice is the most common chilling medium for fresh fish and to avoid a too rapid meltdown of the ice the fish and the ice are best stored in insulated boxes. No reusable insulated fish boxes have been available on the market which in some cases has resulted in poor quality of fresh fish when exposed to warm climates in non-insulated fish boxes. The objective of the project is to provide the fish industry with an improved packaging technology that will maximise quality and safety of the fish products. To design fish boxes according to the demands of the various sectors of the fishing industry, make prototypes, test in real time and compare results with current boxes and tubs. The deliverables required from the project are boxes that fulfil the modern demand for high quality fresh fish quality.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'A Reduction Theory for Codes and Lattices in Cryptography'.

assistant: **Concept**

Codes and lattices are two major mathematical platforms to build quantum-resistant cryptosystems. Theose cryptosystems will soon be standardized and deployed, replacing historical solutions threatened by Shor's quantum algorithm.These new cryptosystems rely on the hardness of finding short vectors in a code or in a lattice, a computational problem called reduction. Our confidence in their security relies on the relentless effort of cryptanalysis: quantifying, elucidating and trying to invalidate such hardness assumptions. *My ERC project aims at discovering faster cryptanalytic algorithms and at building better cryptography via the development of a unified reduction theory enabling a systematic transfer of techniques between codes and lattices.* As an underpinning example for this project, I have successfully transferred the seminal LLL reduction algorithm to binary codes, an algorithm still playing a central role in the cryptanalysis of lattices. This unified theory will also lead to better mathematical and algorithmic abstractions, improve the clarity, generality, and composability of known techniques. Such qualitative enhancements will also help to obtain quantitative ones. In turn, I will implement these enhancements into open-source libraries, designed for either high-performance or ease-of-use, in order to stimulate further algorithmic exploration by the community.Beyond algorithms, my approach will also create new connections between existing mathematical theories and the hardness of code and lattice problems. For instance, it leads to consider moduli spaces as a new powerful tool for proving average-case hardness.By its contributions to both the theoretical and practical aspects of the hardness of lattice and code problems, this project will play a key role in t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Progressive and adaptive learning for object manipulation: a biologically inspired multi-network architecture', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

We propose, in a collaborative effort between Neuroscientists and Roboticians, to develop and implement a biologically inspired multi-network control architecture for the Progressive and Adaptive Learning of Object MAnipulation (PALOMA) by anthropomorphic robots. This control system will incorporate architectural constraints for the interaction among multiple neural networks as defined by available neurobiological data on the connections between and within cortical areas. We will study the open-ended co-operation of successive learning stages for the progressive acquisition of multi-modal hand-object representations and multiple manipulatory tasks with increasing complexity. We will evaluate these learning capacities in two different, evolutionary robotic platforms integrating a hand, tactile sensors, and a vision system, to demonstrate through real-world interaction the feasibility, generality and adaptability of the learning scheme. We propose, in a collaborative effort between Neuroscientists and Roboticians, to develop and implement a biologically inspired multi-network control architecture for the Progressive and Adaptive Learning of Object MAnipulation (PALOMA) by anthropomorphic robots. This control system will incorporate architectural constraints for the interaction among multiple neural networks as defined by available neurobiological data on the connections between and within cortical areas. We will study the open-ended co-operation of successive learning stages for the progressive acquisition of multi-modal hand-object representations and multiple manipulatory tasks with increasing complexity. We will evaluate these learning capacities in two different, evolutionary robotic platforms integrating a hand, tactile sensors, and a vision system, to demonstrate th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Development of an expert system to analyse/optimise the technical/economic feasibility or performance of hybrid large scale solar heating (lssh) systems (expert system lssh)', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

- Large Scale Solar Heating (LSSH) refers to the concept where thermal solar energy is integrated into district heating grids, typically combined with other energy forms (synergies);- LSSH has been proven on approx 50 applications in some European countries, but is almost unknown in others. This, despite the competitiveness vis-a-vis conventional energy concepts;- The development of a management tool shall allow for an integrative analysis of project feasibility (pre-evaluation) and the project s post-evaluation;- The tool shall be in the form of an expert system. While this implies a high degree of complexity, the computer program shall be designed as a Windows application (user-friendly dialog level). Testing and calibration will ensure the soundness of the project result. Extensive dissemination of the expert system and of application results (validation) shall support growing LSSH application on n European level.Urban Catalyst has demonstrated how temporary use is an important urban resource, which can play a strategic alternative in capital-oriented urban development concept soffering new models for action where traditional urban planning tools are inadequate. Case studies have demonstrated how, in a context of economic stagnation, the temporary use of abandoned sites based on low cost appropriation, non-monetary exchange, and program-matic experiment can generate new activities. The Urban Catalyst research partners have compiled an unprecedented archive of best practice projects and existing tools, which give valuable insights into stakeholder networks and offer new answers to the above questions. Most significantly the research shows how unconventional alliances between stakeholders can take place, and lead to mutual benefit. By providing profit-free space for te
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Advanced web tool for Isothermel Titration Calorimetry data analysis and managent'.

assistant: **Concept**

Isothermal titration calorimetry (ITC) is a powerful biophysical method to study intermolecular interaction that has become widely used due to its technological advances. It enables the determination of all thermodynamical parameters of interaction after a single one-hour experiment. The key step of experimental data analysis is the fitting of obtained data using an appropriate binding model. Unfortunately, the limited set of models offered by manufacturers does not allow the full use of ITC for the study of complex molecular mechanisms of interaction. Recently we faced this problem when trying to investigate tau-tubulin binding. Because of its implication in cancer and neurodegenerative diseases this interaction presents great interest for both European host (CRO2) and my lab. Here I propose to create an advanced ITC data analysis tool that will allow researchers to create and share new binding models, so that any ITC end user can upload their experimental data and fit it using available models. This tool will also offer ITC data management and collaborative facilities. It should become a professional social network for ITC end users in Europe and beyond.Using this tool, in the host institution, I will first focus on deciphering the exact mechanism of tau-tubulin interaction which, despite extensive study, remains unknown. I will then study the interplay between tau and anticancer drugs. This will allow us to evaluate the impact of anti-tubulin drugs used in cancer treatment on tau mechanism of action. During the return phase I will study the influence of two key factors implicated in neurodegenerative disorders, oxidative stress and zinc ions, on tau-tubulin interaction.My experience in ITC and multidisciplinary skills combined with the expertise and resources of the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Geometry and analysis of the first eigenvalue functional' (GAFEF).

assistant: **Innovation**

The project is devoted to the study of the first eigenvalue problem for the Laplace operator in geometric settings. The starting ideology is to regard the first eigenvalue as a functional defined on a suitable set of Riemannian metrics, and the main objects of the study are the corresponding extremals. More precisely, the objectives are to study the existence and the properties of extremal metrics. The methods and intuition are both analytic and geometric and involve, for example, the analysis of the concentration phenomenon and the development of the regularity theory. The project is on a quickly developing area which borders with a number of disciplines, and at the moment only isolated results are proved on the rigorous level. Therefore, any progress would be interesting for experts and would advance the researcher greatly towards attaining an independent position.