RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Chemical Biology for Tuberculosis Research' under Seventh Framework.

assistant: **Concept**

The aim of the proposal is the establishment of a yeast-three hybrid system for the identification of mycobacterial proteins that bind to selected small molecules. It is envisioned to use the system to (i) find targets of active molecules that have been identified in whole cell screenings; (ii) identify mycobacterial proteins that activate or deactivate drugs; (iii) establish simple assays for proteins previously identified as key targets. Since the identification of protein targets of a small molecule drug is challenging, improved methods are asked that facilitate their discovery. With the recent development of an optimised yeast three-hybrid system in the Johnsson group, the stage is set for its application to identify small molecule-protein interactions. This adapted version of the classical yeast two-hybrid system features an additional third synthetic hybrid ligand. It uses SNAP-tag (a self-labelling protein tag) as an anchor protein and O6-benzylguanine (BG) derivatives as synthetic ligands. Currently it allows the screening of human cDNA libraries for small molecule-protein interactions in yeast. To apply this system for drug discovery against tuberculosis, the construction of genomic libraries of M. smegmatis was initiated and libraries of M. tuberculosis will follow. We would start with conjugating known TB drugs (with known or unknown targets) to BG and screen them against genomic libraries. Suggested drugs to start are rifampicin and BTZ as positive controls and clofazimine and thiocarlide as drugs with unclear mechanism of action. Noteworthy that the three-hybrid screen can also be applied for the identification of proteins that activate a certain drug. Furthermore, once a protein-ligand is identified, the hybrid assay can be used to screen for new drugs aga
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The role of Europe in world-wide science and technology monitoring and evaluation in a context of global competition' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

Objective: A quantitative empirical approach to delineate, analyse, monitor and evaluate scientific and technological (RTD) developments for strategic, socio-economically relevant policies. This will be achieved by the combination of two methods: (I) the creation of strategic maps of RTD fields, and (2) a strengths & weaknesses and research profile analysis of main actors. The approach is primarily based on the quantitative analysis of scientific and technological literature. However, a major element is the integration of our quantitative approach with knowledge provided by expert opinions. The design of the project is such that the role of Europe in science and technology can be compared immediately with relevant developments in Europe's main competitors: US, Japan, and the Asian Tigers. The main lines of the project are the following A crucial question is how to delineate an RED field -with its actors- in a comprehensive way, so that both mainstream and leading edge of today as well as the more 'peripheral' work -which might become important in the near future- are covered. Science and technology are represented by a vast amount of publications and patents. These 'pieces of knowledge' are interconnected through a gigantic network of common words and references. We develop an advanced method -'bibliometric' cartography'- to unravel this network and to map the underlying patterns. These structures are not the result of any pre-determined definition or classification system. They are, in fact, fingerprint of science and technology as a highly complex, self-organising system. Time-series of these maps represent the dynamics of RTD fields. Identification of the main actors in the fields and positioning of these actors -world-wide- on the maps enable us to visualise cogniti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Novel approaches to Finnish industrial computing' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Center for Scientific Computing (CSC) is the Finnish national center for high-performance computing and networking. It runs a large-scale facility for computational science and engineering and its customers come from universities, research institutes and industry. CSC is also responsible for the operations of the Finnish university and research network (FUNET). As a TTN, CSC specializes in high-end numerical simulations on parallel supercomputers using state-of-the art numerical methods and parallelization strategies. Our special expertise includes computational physics, chemistry and biology, CFD and structural analysis together with visualization and high-performance networking techniques.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'PHOtonic-based full DIgital Radar' under Seventh Framework.

assistant: **Concept**

PHODIR project aims to study, design and realize a full digital transceiver radar demonstrator based on photonic technology both for signal generation and for RF received signal processing. Hybrid technologies merging second generation optical systems and conventional radar architecture could be the answer to issues deriving from electronic devices poor performances such high SFDR (Spurious Free Dynamic Range) and high phase noise level that are nowadays impeding the construction of a fully digital radar transceiver. Starting from a conventional radar architecture, the generation of high frequency signals in the optical domain at the transmitter section and the use of ultra-high bit rate and short width optical pulse train for RF received signal sampling are the main solutions we are going to investigate in the project to overcome problems related to electronic devices. The innovative research aspects of the proposal are: -Definition of a new full digital radar transceiver architecture based on photonic technology -Development and realization of new electro-optic second generation devices -New parallel signal processing algorithms. The most important benefits arising from the project are: -Electro-optic system integration -New technological development in the design of advanced photonic devices -New technological/scientific development in the design of high performance radar CNIT can provide an high level of experience in the field of photonic devices design and implementation and radar system analysis and design. Theoretical support and experimental test-bed thanks to instrumentations and competences in very high-bit rate Gb/s Optical Time Division Multiplexing Systems and techniques for ultra-fast optical sampling are also provided by CNIT.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'The first Large European Antenna with a diameter larger than 5 meters'.

assistant: **Objectives**

Terrestrial demands on space missions are increasing rapidly in terms of complexity, technology and velocity. Next to navigation (GPS, GALILEO), science (investigation of space and the universe) and exploration (ISS, Mars), two types of space missions are very important for Europe: Earth Observation (EO, for the sustainability of nature and mankind) and Telecommunication (TC, for business and global connectivity). Each mission requires partly unique technologies, which are produced by only very few global suppliers. If these technologies are not available from within Europe, there is a danger that non-dependent missions may not be performed, created and tailored with a consequent loss of sovereignty in political decisions and a loss of market shares. One of these so-called “Critical Technologies” is the “Large Deployable Reflector (LDR)”. Packed in stowed configurations, these reflectors can be accommodated on satellites, which then still comply with the limited launcher fairing volumes. By enlarging the size of the reflector it is possible to offer higher sensitivity and resolution, e.g. for radar missions (EO & science) and implement stronger communication links for e.g. higher data throughput (TC). Within the upcoming eight years the demand for such reflectors will increase worldwide, whereas the Consortium targets a certain market share with its “Large European Antenna (LEA)”. The proposed H2020 project would now enable the combination of the technologies previously developed by the consortium members and the joining of further European entities to fill the remaining gaps and form one strong and complete European team. Through obtaining an EC-grant for LEA, each building block will be upgraded with innovation, adapted to a scenario and qualified to meet one common t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'New Methods to PRevent, Investigate and Mitigate COrruption and TAX Crimes in the EU'.

assistant: **Concept**

PROTAX will contribute to a European Security Model providing solutions for prevention and prosecution of tax crimes. Based on analysis of current approaches of law enforcement, legal frameworks at Member State level and in-depth empirical investigation of human factors, shaping institutional and professional practices of stakeholders PROTAX will develop in close co-operation with practitioners tool kits for security policy makers, law enforcement agencies and tax authorities. They will combine high use-value with a strong European perspective, paving the way towards an integrated European approach. Since serious and organised tax crimes often involve cross-border activities, requiring cooperation across national jurisdictions a shared understanding of risks, threats and security measures will improve European law enforcement practices. PROTAX will produce innovative solutions boosting evolutionary development towards a genuine and sustainable European approach, significantly reducing the damages for European societies caused by criminals in the financial sector.PROTAX adopts a five-pronged approach. 1. We use case studies of tax crimes to investigate the roles of various actors. 2. We conduct focus groups with stakeholders in Member States. 3. We focus on the role of professional enablers as facilitators allowing illicit financial flows through legitimate institutions. 4.We map out various legal and enforcement approaches across the EU. 5. We make recommendations and provide a toolkit improving prevention of tax crimes and enforcement of the law. PROTAX will involve experts from LEAs and tax authorities in structured exchanges to share experience and ideas. A focus will be on cross-border aspects, assuming that tax crimes spread from “source countries” across the EU (e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Enabling safe & secure modular UPdates, UPgrades and DynAmic Task reallocation and Execution for Software Defined Vehicles' (UP2DATE4SDV) under Horizon Europe.

assistant: **Objectives**

UP2DATE4SDV has brought together automotive hardware manufacturers, the automotive software industry and SMEs, and the best-known researchers in the field to jointly create a comprehensive ecosystem for updatable, upgradable, and reconfigurable software-defined connected and automated vehicles. To this end, a middleware solution is to be created and integrated into the current automotive open source standards, which allows complete abstraction not only of the software running in the vehicle, but also of the installed hardware. As a result, not only can the software be continuously updated over the air over the lifetime of the vehicle and thus kept safe, secure, and up to date, but hardware components can also be easily replaced or supplemented to meet future requirements. To achieve this, we will additionally develop a new hardware component based on established automotive systems, which will be expanded in such a way that the unavoidable overhead resulting from the update capability of the systems is minimised thanks to explicit hardware support.The overall solution is suitable for the upcoming zonal E/E architectures that have a permanent connection to the cloud. The project therefore aims to develop and integrate methods that ensure the safety of the systems during an update by strictly separating all individual automotive applications in containers. In addition, a security layer will be introduced to prevent attacks via the cloud link or among the application modules.Finally, we want to make it easier for automotive software developers to use our middleware by establishing a reference layer based on a hypervisor that prevents the real-time requirements of different application modules from influencing each other. Communication to the vehicle components and to the cl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Young Academics Doctoral fellows IAS'.

assistant: **Concept**

The Young Academics Doctoral fellows IAS (YADIAS) programme within the Marie Skłodowska-Curie Actions (HORIZON-MSCA-COFUND) is a career development programme offered by the University of Luxembourg (Uni.lu) to encourage young researchers, doctoral candidates, to gain momentum in interdisciplinary and intersectoral research. YADIAS will finance 15 interdisciplinary, international, and intersectoral doctoral fellowships. YADIAS applicants are international talents willing to propose and realize their own interdisciplinary doctoral research project through a bottom-up approach. The 15 YADIAS Doctoral Candidates (DC) will be recruited with individual fellowships of 48 months. YADIAS is explicitly open to all disciplines and sectors, involving the entire University in the drive towards an increased interdisciplinarity, which is considered strategic for Uni.lu, for Luxembourg and Europe. Uni.lu’s rationale is based on the consideration that the world’s challenges are so multifaceted and intricate that they can only be solved through interdisciplinary, intersectoral and international approaches.


**Keywords:** Institute for Advanced Studies, doctoral education and training, interdisciplinarity, excellence, internationality,career development, transferable skills, gender equality, mentoring, sustainability
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Near Field Optics for Nanotechnology' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

. Group level: Each young researcher will get training of the specific capa-Near field optics has a great potential to become an imaging and bilities of the lab. She or he will be required to give training of her/ characterization tool for the nano-age. Work on the technique is needed in his speciality to graduate and undergraduate students. three areas:  applications. This network will prodive solutions by exploring novel . Network level: 6 training weeks organised by the participating groups will concepts of light concentration to nanometer dimensions, including give the young researchers the possibility to present and defend their transmission line probes and apertureless, scattering probes. An important work.  aspect is the investigation of the dynamics of the probes, i.e. the conferences structured and at a level similar to NATO ARW's with invited frequency response.  speakers from outside the network  storage applications we will create nanometer sized structures. They . Industrial level: Stages at industrial companies will be available. will be based on ferroelectric materials and on strong plasmon materials. The dynamics of these structures as well their spectral properties will be evaluated.  with color imaging capabilities, opening the field of visualization to biology, medicine and environmental problems. Theoretical and experimental studies of the resolution, image interpretation (to avoid misjudgements) and data storage belong to this area. In close collaboration with industry we will tailor the tools to be readied for technology. Though not directly involved industrial
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Numerical evolution of realistic binary black holes: application of the dynamical horizon formalism to the accurate estimation of physical parameter in gravitational waves' (BBHEVOL).

assistant: **Concept**

Gravitational waves physics constitutes one of the most vigorous lines of research in gravity physics, as well as a radically new avenue in astronomy. Extraction of astrophysical information from the gravitational wave data collected by interferometric gravitational antennae, demands the accurate modeling of the sources.Binary black hole coalescence represents a singularly important astrophysical source for gravitational radiation, whose dynamics must be studied by using numerical relativity techniques. The precise characterization of the individual black hole physical parameters, during the evolution of the system, is critical for the correct interpretation of the observational data. This defines the main goal of this project: the accurate determination of black hole parameters and corresponding emitted waveforms, in the numerical evolution of astrophysically realistic binary black holes configurations.This ultimate goal is structured in three partial objectives:- translation of the local description of black holes (dynamical horizons) into the schemes employed in numerical relativity;- numerical construction of binary black hole spacetimes by using the spectral methods implemented in the C++ Lorene library (Meudon group); and- extraction of the astrophysical relevant content.This program naturally continues the applicant's work during his previous Marie Curie Fellowship, devoted to the construction of binary black hole initial data. The final outcome of the present project would consist in a set of accurate gravitational waveforms to be used in the analysis of observational data.The IAA-CSIC gravitation group provides an excellent setting for the re-incorporation of the applicant: it would enable him to join an interdisciplinary program in black hole horizons research
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Adaptation genomics of trophic polymorphism' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Identifying the determinants of species diversification is one of science’s most pressing questions. Biodiversity research has direct implications for our understanding of the origins of species, unequal species richness and the origins of phenotypic and evolutionary novelty, and is therefore an FP7 research priority. Critical elements in understanding the evolution of biodiversity are the environmental and genetic factors that influence adaptation. Similarly, we need to understand these ecosystem components in order to mitigate biodiversity loss under rapid climate change.The latest advances in DNA sequencing technology make it possible to study the genomes of non-model species (i.e. populations in nature) and the genetic bases of their ecological diversity. In this proposal, novel DNA sequencing approaches will be used to investigate long-standing, compelling questions of ecology and evolution. Specifically, the proposal seeks to address two inter-connected objectives in the genomics of adaptation: 1) to determine differential gene expression associated with rapidly evolving and phenotypically plastic trophic polymorphisms; 2) to quantify genetic variation and its response to selection in the divergence between trophically polymorphic species, and then to identify its arrangement in the genome. The study organisms are polymorphic species of salmonid fishes native to Europe.The Researcher will be hosted by the Institute for Biodiversity, Animal Health and Comparative Medicine, University of Glasgow. This is a world-class research facility for the study of ecology and evolution, and will subsequently integrate the Researcher. The Researcher will bridge research priority areas across the University and foster regional and international collaborations. Launching from this