RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Chimeric Influenza-VLP used as vaccine platform for presentation of foreign antigens - Application to Malaria antigens' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The goal of this project is to provide a new antigen delivery system for vaccination purpose. We want to develop a vaccine platform based on pseudo-viral particles (VLP), able to enhance antigen immunogenicity and allow for screening multiple antigens independently or simultaneously. A chimeric influenza-VLP platform will be construct, where hemagglutinin (HA) protein will be modified to accommodate exogenous peptides containing B- and/or T- cell epitopes, thus allowing foreign antigen incorporation. The first objective is to select the best chimeric influenza-VLP construction to increase immunogenicity of vectorized antigens. The second objective is to provide a robust and scalable production process and a well-characterized chimeric influenza-VLP platform. The third objective is to validate our vaccination strategy by assaying its efficacy with malaria antigens to immunize against parasite infection and/or blood-stage development of the disease. The strength of this project and its high likelihood of success are based on a synergistic collaboration between three internationally recognized laboratories that would bring their complementary expertise to reach the ultimate goal of the project: delivering a new malaria vaccine-candidate. This will be supported by a complete characterization of the production process and of the final product for transfer to industrial manufacturing. The laboratory VirPath of Pr. Lina, will bring its expertise on influenza virus and vaccine production. Laboratory of Dr. Kamen NRC-Montréal developed for 2-3 years an influenza-VLP production technology based on HEK293 cells. We will transfer and exploit this know-how to select the best production process for chimeric influenza-VLPs and further optimize it. Choice of malaria target antigens and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Design of a serious game for cars to help increase driver skills and lower fuel consumption'.

assistant: **Objectives**

New in-vehicle information systems and advanced driver assistance systems are currently being introduced in cars in order to help driving safely and energy efficiently. These systems help the driver to pay attention to critical events (e.g. collision warnings and blind spot information systems) or deliver important information (e.g. speed limits and navigation instructions). However, safety and environmental impact are most of all dependent on the behaviour and attitude of the driver. This proposal concerns the design of a serious game for cars that will help drivers to increase eco-driving skills, lower fuel consumption and encourage safe and environmentally friendly approaches to driving. Through his research, Dr Arne Nykänen has developed successful methods and procedures for efficient product sound design, already implemented at Volvo Cars and Scania. Anglia Ruskin University has leading expertise on creative and user-centred design, serious gaming, mobile applications and sound design for theatre and film. Combining this expertise enables the introduction of sound based serious gaming in cars. This provides a successful way to increase driving safety and decrease environmental impact of cars, by not only informing and warning the driver, but also changing attitudes and behaviour. The major outcomes of the project will be a demonstrator of a serious game implemented in a car, a mobile app publicly available for download, demonstrations at science centres in the UK and Sweden, 3 journal papers, participation in 4 conferences, and a new European expert network with partners from academia as well as car, game and audio engineering industry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Mixed Haptic Feedback for Mid-Air Interactions in Virtual and Augmented Realities' in the context of a Horizon 2020 call.

assistant: **Objectives**

“Touch comes before sight, before speech. It is the first language and the last, and it always tells the truth” (Margaret Atwood), yet digital content today remains focused on visual and auditory stimulation. Even in the realm of VR and AR, sight and sound remain paramount. In contrast, methods for delivering haptic (sense of touch) feedback in commercial media are significantly less advanced than graphical and auditory feedback. Yet without a sense of touch, experiences ultimately feel hollow, virtual realities feel false, and Human-Computer Interfaces become unintuitive. Our vision is to be the first to imbue virtual objects with a physical presence, providing a revolutionary, untethered, virtual-haptic reality: H-Reality.The ambition of H-Reality will be achieved by integrating the commercial pioneers of ultrasonic “non-contact” haptics, state-of-the-art vibrotactile actuators, novel mathematical and tribological modelling of the skin and mechanics of touch, and experts in the psychophysical rendering of sensation. The result will be a sensory experience where digital 3D shapes and textures are made manifest in real space via modulated, focused, ultrasound, ready for the untethered hand to feel, where next-generation wearable haptic rings provide directional vibrotactile stimulation, informing users of an object's dynamics, and where computational renderings of specific materials can be distinguished via their surface properties.The implications of this technology will be far-reaching. The computer touch-screen will be brought into the third dimension so that swipe gestures will be augmented with instinctive rotational gestures, allowing intuitive manipulation of 3D data sets and strolling about the desktop as a virtual landscape of icons, apps and files. H-Reality w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Role of technologies in an energy efficient economy – model-based analysis of policy measures and transformation pathways to a sustainable energy system' (REEEM) under Horizon 2020.

assistant: **Objectives**

REEEM aims to gain a clear and comprehensive understanding of the system-wide implications of energy strategies in support of transitions to a competitive low-carbon EU society. Comprehensive technology impact assessments will target the full integration from demand to supply and from the individual to the entire system. It will further address its trade-offs across society, environment and economy along the whole transition pathway. The strong integration of stakeholder involvement will be a key aspect of the proposal. The assessments performed within REEEM will focus on integrated pathways, which will be clustered and categorised around two focal points: the four integrated challenges of the Integrated Roadmap of the Strategic Energy Technology (SET)-Plan and the five dimensions of the Energy Union. Case studies will further serve to investigate details and highlight issues that cannot be resolved at a European level. A range of outputs will target the specific needs of various stakeholder groups and serve to broaden the knowledge base. These include, among others, Policy Briefs, Integrated Impact Reports, Case Study reports and Focus Reports on economy, society and environment. A focus on technology research, development and innovation will be included through the development of Technology Roadmaps with assessments of the Innovation Readiness Level of technologies. Further, a set of enabling tools will help to disseminate and actively engage stakeholders, including a Stakeholder Interaction Portal, a Pathways Diagnostic Tool and an Energy System Learning Simulation. Access to all work developed and transparency in the process will be guiding principles within this project exhibited by, for example, providing open access to a Pathways Database.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Large High Rise Reconversion Housing' (SUNRISE), addressing dissemination and exploitation.

assistant: **Impact**

- To demonstrate innovate energy efficient solutions at large scale housing;- To integrate these solutions, also bringing better appealing architecture (specially for high rise and reconversion);- To reduce energy consuming and demonstrate solar tools integration at large scale, by that reduce CO2 and pollutant emissions by more than 50;L%- With coordinator and 4 horizontal task guidance the large project will bring together large public and private developers of 10 EU countries, improving their individual projects and developing the market spreading of these strategy and results through EU networks and over Europe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Functionalized ceramic membrane filter for highly efficient soot particle removal' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Objectives and content Recent findings correlating mortality rates in cities with concentrations of fine particles smaller than approximately 2.5 microns prompt for increasingly tighter legislation in terms of reducing particulate burden on the environment. Soot particles emitted from combustion sources occupy a central position among the total amount of emitted particles in the less than 2.5-micron size range. Although combustion process modifications have been actively pursued both for stationary and mobile sources, it is commonly felt that meeting future particulate emission standards will not be feasible without aftertreatment devices. The present Industrial Research project addresses the problem of developing advanced ceramic filters for soot particle emissions control with the following main objective: To overcome problems of currently available ceramic filter technology in terms of material reliability, pressure drop, collection efficiency for fine particles and ease of cleaning (regeneration" by oxidation of collected soot) at a lower cost than competing nonEuropean technology by integrating:  A silicon carbide (SiC)-based extruded monolithic filter, with very high collection efficiency (>99%) for nano-sized particles, low-pressure drop and high material reliability. A two layer gradient filter structure (a filter membrane with an overlaid highly porous "foamy" layer) functions at the same time as a fine particle separator and as a soot oxidation reactor, through a catalytic coating dispersed into the entire ceramic microstructure.  Advanced catalytic coatings for soot oxidation incorporated into the filter microstructure. Two types of novel catalytic coatings will be developed: Physical Vapour Deposition (PVD)-based nanoscale catalysts and Supported Liquid Phas
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Combat on-line illegal numismatic sales' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

The COINS project aims at providing a substantial contribution to the fight against illegal trade and theft of coins which appears to be a major part of the illegal antiques market. For this goal, state-of-art Information Technology will be used. The project will develop standardized inventories by defining a domain ontology based on CIDOC-CRM, the standard ontology for Cultural Heritage, and a multilingual thesaurus. Data management tools will be created as well, and a specialized web search tool.The recognition of coins will be based on new algorithms of pattern recognition and image processing, in a field (classification and identification of ancient coins) as yet unexplored. The project will disseminate its results also by means of a demonstrator freely accessible on the Internet. Substantial contribution to the project will come from stakeholders, some of which are present in the partnership, which includes the Italian law enforcement organisation Carabinieri and three major national museums with important coin collections.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Communication through Polarity-Switchable Foldamers' under Horizon 2020.

assistant: **Concept**

We propose to develop a new, artificial but bio-inspired mechanism for communicating information in chemical systems, by using the potential for hydrogen-bond reorganisation of novel dynamic 'refoldable foldamers', combined with biology's information storage mechanisms. Biological information is encoded in DNA or RNA by two dimensional arrangements of hydrogen bond donors and acceptors in nucleotide sequences: we will innovate nanoscale communication devices that read information encoded in this way, and translate it directly into a chemical feature (catalytic activity, ligand-binding ability) at a site remote from the source of information. Conceptually we shall telescope the biological processes of transcription and translation into a single conformational event in a single molecule.We will develop a new class of polarity-reversible foldamers as artificial receptors to translate information stored in hydrogen bonding patterns into a local conformational preference.  The preference will be communicated the full length of the foldamer by means of a global change in shape, and used to define the detailed structure and hence spectroscopic and chemical properties at another site in the molecule. Those devices will mimic biology’s ability to communicate information in a manner reminiscent of the G-protein coupled receptor. Dynamic foldamer conformational switching will be based on reversible hydrogen-bond polarity rather than on helical screw sense switching recently used by Clayden to carry information: reversal in directionality of hydrogen bond networks has not yet been exploited.Success would open up a new area of science at the boundary of synthetic chemistry and biology, facilitating new developments in as-yet untapped applications of dynamic foldamers, improving Euro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Understanding gene regulation in nuclear space' (Hotspot), addressing dissemination and exploitation.

assistant: **Impact**

There is accumulating evidence for a new gene expression paradigm, in which genes and transcription factors cooperate to create specialized nuclear hotspots optimized for transcription. How hotspots form, and how they impact transcription, however, is unclear. This is mostly because mechanistic and functional approaches have been limited by the large number of hotspots per nucleus, their small size, and their transient nature. Here, wThere is accumulating evidence for a new gene expression paradigm, in which genes and transcription factors cooperate to create specialized nuclear hotspots optimized for transcription. How hotspots form, and how they impact transcription, however, is unclear. This is mostly because mechanistic and functional approaches have been limited by the large number of hotspots per nucleus, their small size, and their transient nature. Here, we will take advantage of two hotspots that precede all other transcription during zebrafish embryogenesis. The hotspots are large, isolated, and relatively long-lived, and we can interfere with their formation specifically. They therefore provide an excellent opportunity to study nuclear hotspots. The stereotyped activation of transcription during embryogenesis further provides the opportunity to determine the effect of hotspots on gene expression. In Aim 1, we will determine what triggers hotspot formation, identify the components of hotspots and the order in which they come together, and determine the enrichment of components in hotspots compared to nucleoplasm. In Aim 2, we turn our attention to the genes that come together in these hotspots. We will develop a method to visualize single copy genes live and use this to determine how genes come together in transcription hotspots to be activated. Together, the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'EMpowering transatlantic PlatfOrms for advanced WirEless Research' in the context of a Horizon 2020 call.

assistant: **Objectives**

EMPOWER ambitions to accelerate the joint development between the EU and the US on advanced wireless platforms targeting the new connectivity frontiers beyond 5G. EMPOWER targets the creation of a joint EU-US advanced wireless ecosystem for (i) bridging the relevant EU-US Wireless communities and stakeholders, such as scientific researchers, platform engineers, standardization experts, regulators, and product incubators; and (ii) developing a strategic EU-US collaboration agenda and supporting its execution ahead of worldwide competition for beyond 5G connectivity standards. EMPOWER foresees twinning with the best researchers and practitioners involved in projects funded by USA, especially with entities participating in the PAWR programme (https://www.advancedwireless.org/). EMPOWER will provide instruments for inducing collaboration between ongoing and forthcoming 5G and beyond initiatives targeting at wireless networks experimentation on both ends of the Atlantic. Through the EMPOWER instruments we aim to create an efficient means for stimulating the circulation of ideas and people between European and similar American experimental wireless platform initiatives. We also aim at encouraging stronger collaboration between fundamental and experimental wireless researchers by making access to platform tools and data exchange simpler. EMPOWER instruments will also provide a wealth of information for global and regional standards and regulatory organizations (e.g. ITU-R, ETSI) and industry fora (e.g. NGMN). An important additional output of EMPOWER will be in the form of recommendations on technologies and experimentation methodologies for future wireless experimentation objectives. This will assist in providing coordination between EU (Horizon Europe) and US NSF programmes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Environmental impact of organic waste recycling by composting' (ENVISOL), addressing dissemination and exploitation.

assistant: **Impact**

The release of airborne microorganisms from organic waste treatment plants is raising concerns due to the potential health risks for site workers and local residents. The training of the applicant under a Marie Curie Program has focused on the generation a nd dispersion of airborne microorganisms at different waste treatment plants (mainly composting plants) in the UK. The present proposal is intended to apply the knowledge gained by the applicant to the specific conditions of the Mediterranean countries fro m southern Europe (warmer climates and different life style). The objective of this project is to assess the effect of the specific conditions of the Mediterranean countries, such as higher temperatures and different organic waste composition, on the amoun t of airborne microorganisms generated and the dispersion patterns. To achieve this, the research involves air monitoring at different full scale composting plants in operation in southern Spain to assess the amount of bioaerosols generated under their spe cific conditions. The research also involves the use of a pilot scale composting plant that facilitates modifying different operational aspects of the plant to establish the main factors affecting bioaerosol generation and dispersion. The output of the res earch will be twofold. First, to establish to what extent the different environmental and weather conditions of different regions of Europe will affect the bioaerosol generation and dispersion patterns. Secondly, to study the potential application of this methodology to different areas such as farming and food processing companies, that represent the main economical activities of these regions.