RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Laboratory Skin Patches and SmartCards based on foils and compatible with a smartphone'.

assistant: **Objectives**

Conventional analytical methods often require a large sample volume and complicated time-consuming protocols. The objective of this project is to develop ultra low cost laboratories on chips (LOC) without penalisation in time response, sensitivity or simplicity of use. The user will obtain the test results using a very popular interface (a smartphone) and a set of Labcards and Skin Patches where the sample preparation and detection take place. The project will validate the Labcard in three applications: (i) climate prediction by sea CO2 absorption through algae detection, (ii) Salmonella and Campylobacter typing in slaughter houses and farms and (iii) Colorectal Cancer monitoring using blood; and the Band Patch in Cocaine consume in professional drivers through sweat.The new devices will consist of a LOC embedded in a Smartcard or a Skin Patch. The LOC will integrate the Microsystems (valves, pumps, reservoirs, heaters, Organic LEDs and electronics) and Biotechnology (reagents, enzymatic reactions, immobilised layers). This combination will produce a testing system requiring no sample preparation from the user. The Labcard and Skin Patch will be fabricated using a reel-to-reel system decreasing the price to 1% of existing systems (by replacing wafer based substrates with large films based systems).The project involves 15 partners from 8 countries. They are European leaders in their fields. They represent public (2 research centres and one medical institution) and private sector (6 SMEs and 6 technological centres).The Labcard will provide new solutions for crisis management (e.g. food poisoning or global warming) and will require small samples to obtain the diagnostic. The Skin Patch will allow controlling the abuse of drugs or analogue substances, and studying time-evo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Nano-particle characterization and toxicity' (NANOTOX) under Sixth Framework.

assistant: **Objectives**

Given the current manufacture growth, presence of nano-particles (NP) in the environment and the future use of NP, human exposure is inevitable. Yet, the potential adverse effects on human health from exposure to NP are still largely unknown.This propos al outlines a strategy for determining how the physicochemical properties of NP influence there potential for toxicity at the National Institute of Occupational Health, Denmark and University of Copenhagen. Specifically, a wide range of NP will be characterized for their size, shape, surface area, solubility, and chemical composition.Experiments will be performed with human epithelial cells to determine the NP potential for toxicity by measuring reactive oxygen species (ROS) generation, pro-inflammatory cytokines, apoptosis, and DNA oxidative damage. By comparing the physicochemical properties of NP with their potential for toxicity, we gain the ability to predict the toxicity potential for existing and novel NP exposures.Without safety assessments and clear communication with the public and regulators, nanotechnology and the use of NP could potentially be restricted, which may hinder the economic future of Europe.This research involves the translation of physical science techniques to advance understanding of an important medical issue and mutually benefits from an ongoing and expanding nanotoxicology program at the host institute, which currently includes in vitro, in vivo and hazard evaluation aspects.My career goal is to become active in Medical Geology and Nanotoxicology. This fellowship would prove extremely valuable for my career training and serve as a springboard for future intra-Europe and cross-Atlantic collaborations.By combining several established and novel techniques from various disciplines with a well-de
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Tumor cell death supports recurrence of cancer' (Cancer-Recurrence).

assistant: **Concept**

Introduction: Current anti-cancer treatments are often inefficient, while many patients initially benefit from anti-cancer drugs eventually experience relapse of resistant tumors throughout the body. Current clinical strategies mainly aim at inducing tumor cell death, but this induction may have unintentional and unwanted side effects on surviving tumor cells.Preliminary data: We show that after chemotherapy-induced initial regression, PyMT mammary tumors reappear. During regression, we observe an increased number of cells that have undergone epithelial-mesenchymal transition (EMT) and become migratory. We show that migration can be induced upon uptake of extracellular vesicles (e.g. apoptotic bodies). Our findings suggest that EMT is induced upon chemotherapy, through e.g. EV uptake, potentially leading to migration and growth of surviving cells.Hypothesis and main aim: Based on preliminary data, we hypothesize that tumor cell death induces migration and growth of the surviving tumor cells. We aim to identify the key cell types and mechanisms that mediate this effect, and establish whether interference with these cells and mechanisms can reduce recurrence of tumors after chemotherapy.Approach: We have developed unique intravital imaging tools and genetically engineered fluorescent mice to visualize and characterize if and how dying tumor cells can affect surrounding surviving tumor and stromal cells. We will test whether dying tumor cells can influence the growth, migration, dissemination and metastasis of surviving tumor cells directly or indirectly through stromal cells. We will identify potential targets to block the influence of the dying tumor cells, and test whether this blockade inhibits the unintended side-effects of tumor cell death.Conclusion: With the studie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Transport Innovation Deployment for Europe' (TIDE).

assistant: **Concept**

The mission of the TIDE project will be to enhance the broad transfer and take-up of 15 innovative urban transport and mobility concepts throughout Europe and to make a visible contribution to establish them as mainstream measures. The TIDE partners will make a range of new and feasible solutions easily accessible to address key challenges of urban transport such as energy efficiency, decarbonisation, demographic change, safety, access for all and new economic and financial conditions.TIDE will focus on 15 innovative concepts in five thematic clusters: financing models and pricing measures (1), non-motorised transport (2), network and traffic management to support traveller information (3), electric vehicles (4) and public transport organisation (5). Sustainable Urban Mobility Plans will be a horizontal topic to integrate the cluster activities.The project will provide a strong approach in methodology, content and outreach. The needs of practitioners in European cities and regions will be a guiding principle. A particular focus will also be on providing guidance for finding cost-efficient solutions (cost-benefit analysis).The project will refine existing and well proven transferability methodologies and integrate them into an easy to apply handbook. Face-to-Face training and exchange events as well as guidelines ande-learning on how to successfully implement innovative solutions will be the key tools to effectively support a wide range of take-up candidates in overcoming real or perceived barriers to implementation. A broad portfolio of dissemination activities will ensure a high visibility of the project.TIDE will actively support 15 committed cities in developing implementation scenarios. They will demonstrate how to successfully prepare implementation of innovative s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Vacuum insulation (VACI)' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Insulation methods are among the most important aspects in many applications. Conventionally used materials are often considered suboptimal in terms of environmental issues, space requirements, and performance. Depending on the nature of the application, these drawbacks can become costly and possibly prohibitive. Hence, the development and introduction of new materials is of great importance. An alternative approach to conventionally employed insulation materials is one that considers vacuum insulation. Laboratory experiments concerning the performance have shown good results, however, to refine the method for commercial exploitation requires further research. The participants of this project have recognized the potential of this new method and believe the availability of such methods would provide access to new horizons. In controlling the intellectual property rights, the SMEs participating would be able to gain a significant competitive advantage, as the application of this method is relevant to many areas of industrial importance. The technical objective of the proposed research is hence the refinement and development of methods, processes, and machinery to manufacture and maintain Vacuum Insulation Panels (VIPs) is a way that will facilitate their use in industrial applications. This implies the development of methods that will allow tapered and bent segments, and it especially requires research regarding the joining of segments. Additionally, the development of machinery and methods to ensure on-site repair or exchange of damaged segments is a topic. The project is expected to contribute to European objectives in a distinctive way. While the unique character of the research involved constitutes a new path and therefore leads to valuable prerequisites that will set
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Understanding the coordination between mitosis and cell polarity in Drosophila', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Shaping the tissues that make an organism requires a tight control of cell division and mechanisms that spatially distribute signalling cues and adhesive structures within single cells. Although cell division and polarity have been extensively studied, how these processes are coordinated is largely unknown.The primary goal of this project is to understand the link between regulation of mitotic cell division and the organization of polarity at the organism level. First, we will use the Drosophila follicle epithelium to set up an in vivo model to address with high temporal resolution how the evolutionary conserved polarity complexes are remodelled at the cell cortex during mitosis in epithelia. We will then characterize the specific function of distinct types of mitotic proteins (Polo, Aurora A, BubR1 and Ndc80) in the organization of the follicle epithelium polarity and architecture, and in germline stem cell asymmetric division. The study in the follicle epithelium will contribute for the understanding of the mechanisms that coordinate the establishment of a mitotic spindle with changes in cortical polarity. In addition, the comparison between these two contexts with distinct cellular features will elucidate the specific requirements of the different mitotic genes.Misregulation of cell division and loss of epithelial organization are a hallmark of cancer. We will therefore test the interaction between polarity proteins and cell cycle regulators to explore new hypothesis for tumour progression. For this purpose, we will determine the ability to overproliferate, invade and metastasize of tissues where we simultaneously interfered with mitosis and polarity. Thus, this work will have implications for human disease, shedding light on the mechanisms of tumorigenesis.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Impact Monitoring of Mineral Resources Exploitation', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

ImpactMin will develop new methods and a corresponding toolset for the environmental impact monitoring of mining operations using Earth Observations. Novel technology will be proposed for the combined use of satellite remote sensing, aerial lightweight measurements and Unmanned Aerial Vehicles (UAVs). The proposed methods will be validated at four demonstration sites in Sweden, Bosnia&Herzegovina, Romania and Russia. The theoretical advancement in science and technology will be made public knowledge with the help of a free multimedia e-learning programme whereas the tools and foreground knowledge will be commercialised by the participating SMEs. The scientific challenge is to use remote sensing technologies to develop cost-effective, reliable and repeatable approaches for monitoring the impact of mining activities on the environment through time, in order to identify, predict and prevent potentially serious consequences for the natural and human environment. On the one hand it is of great importance that the amount of detail obtained from these data sources is sufficient to monitor relatively small changes through time. On the other hand it is essential that the methods used are sufficiently flexible to operate under different circumstances at acceptable cost. The composition of project partnership and the selection of demonstration sites correspond to European interests in both accessing strategic minerals needed for the European economy and the need to monitor and control environmental pollution from these sources.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Evaluation and validation of connected mobility in real open systems beyond 5GS' to be submitted under Horizon Europe.

assistant: **Abstract**

5G adv. and 6G aim to expand the set of supported verticals and provide enhanced capabilities beyond connectivity. 5G CAM vertical services are a broad range of services in and around vehicles, including both safety-related and other services enabled or supported by 5G. 5GS has been built as a modular architecture to support any vertical running on top in a vertical-agnostic manner. However, it is realized that certain verticals (like CAM) have specific and strict requirements. Although significant progress has been made in supporting verticals, the corresponding necessary configuration of the network and end-devices is a time-consuming manual process that requires tight coordination at technical and business levels across the verticals, the vendors, the network operator, and even the end-users. This hinders not only the greater adoption of 5GS but also the uptake of novel CAM UCs and the modernization of existing ones that require a tighter integration with the underlying network. The main objective of ENVELOPE is to advance and open up the reference 5G adv. architecture, and also to transform it into a vertical-oriented with the necessary interfaces tailored to the CAM UCs that i) expose network capabilities to verticals, ii) provide vertical-information to the network; iii) enable verticals to dynamically request and modify certain network aspects in an open, transparent and easy to use, semi-automated way. ENVELOPE aims to deliver 3 large-scale B5G trial sites in Italy, Netherlands and Greece for CAM services and beyond, implementing functionalities tailored to the CAM services and advanced exposure capabilities. Although focused on the CAM vertical, the resulting developments will be reusable by any vertical. The ENVELOPE architecture will serve as an envelope that
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Interoperability Network for the Energy Transition' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Interoperability depends on cooperation of multiple domains. While for the energy sector technical interoperability is quite well established, interoperability of functions and businesses needs more attention. Even when standards are defined and interoperability models agreed, framework setters, product developers and users need to agree on their deployment and make sure that solutions are compatible with definitions. The Interoperability Network for the Energy Transition project (IntNET) establishes an open, cross-domain community bringing together all stakeholders relevant for the European energy sector to jointly work on developing, testing and deploying interoperable energy services. The community will be formally established to exist beyond project life-time. With a comprehensive, FAIR knowledge platform and a series of attractive events it guides those who deal with the heterogeneous interoperability landscape of energy services. To support ongoing harmonization of energy services, IntNET will institutionalise an assessment methodology and maturity model (IMM). Involving legal and regulatory bodies from the beginning and constant exchange of interoperability initiatives and standardization bodies will build a deep consensus on how European governance and industry can foster interoperability at all levels. Starting from an extraordinary well balanced and connected consortium of researchers, framework setters (e.g., ministry and EU wide associations), standardisation and communication experts, IntNET’s community approach guarantees wide outreach. IntNET will establish a framework for interoperability testing in ongoing projects and harmonize test procedures in a network of closely cooperating, self-sustained testing facilities. Energy service solutions based on the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Use of short length timber in furniture manufacture' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

The aim is to develop novel technologies and systems, which exploit neglected resource, by creating a value-added market for the supply of cost-effective, quality raw materials to small and medium sized furniture producers and furniture component manufacturers. The objectives are to:- Add value to short-length timber, currently perceived as low-grade;- Reduce raw material costs and increase competitiveness within the SME dominated furniture industry;- Develop optimal jointing and gluing techniques for the production of furniture components from short-length timber at minimal cost;- Introduce new, profitable and sustainable management systems, which optimise the potential of rural and urban mixed species woodlands.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'The Political Economy of the International Investment Regime', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Since the early 1990s, the number of international investment agreements, bilateral investment treaties, and trade agreements with clauses on foreign direct investment (FDI) has grown exponentially. These agreements between sovereign states regulate the treatment of foreign investors and capital in their territory. By early 2009, the international regime for FDI had evolved into a decentralized network of over 2600 agreements with divergent rules, but lacked any overarching multilateral framework—a stark contrast to the regime for trade. Drawing on the concept of “legalization” (or “judicialization”), i.e. the institutionalization of international relations through law, this project seeks to answer three interrelated questions. First, why have multilateral efforts to create an investment regime repeatedly failed, when bilateral agreements proliferate? Second, what explains the variation in the design of these agreements? Finally, what accounts for the evolution of the investment regime from hortatory declarations to elaborate agreements, enforceable via third-party arbitration? Existing explanations emphasize the competition between developing countries for investment. By contrast, this project hypothesizes that developed countries use international law to require developing countries to adopt and maintain a liberal economic policy. In asymmetrical bargains, major economic powers progressively ratchet up the standards for protection for their investors. The project combines formal models, case studies of the treaty programmes of the US, Japan, and the UK and their negotiations with partner countries, and statistical and quantitative network analysis. By providing a comprehensive account of the evolution of the regime, the project aims to advance our theoretical understa