RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Targeting peripheral nerves: a method for therapeutic modulation of inflammatory disease with non-invasive temporal interference' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Excessive inflammation underlies the development of inflammatory diseases, e.g. Rheumatoid arthritis, Crohn's Disease, inflammatory bowel disease, and cardiovascular disease - the most common cause of death in the world. Human physiology is controlled by defined molecular mechanisms, commonly controlled by specific target nerves and their associated reflexes which optimize function – for example molecular mechanisms regulating inflammation. Harnessing the power of the inherent nerve reflexes which are evolutionarily adapted to regulate specific molecular mechanisms holds promise to overcome many of the drawbacks intrinsic to current drug therapies. This approach, designated “bioelectronic medicine”, presents a radically improved way to both treat and better understand disease – with increased adaptability and precision. The vagus nerve, as shown by the team in this project and other groups, plays a key role in regulating key pro-inflammatory cytokines, pro-resolving mediators, and controls inflammation. However, specific targeting of the vagus nerve has required neurosurgical implantation of a pacemaker-like stimulator device with a control unit, a connecting cable, and an electrode implanted at depth. The requirement for highly specialized surgery significantly limits the usefulness and possibilities for implementation of nerve stimulation in treatment of inflammation. Surgery and device implantation also carries risks for permanent tissue damage, local inflammation, infection, and other potentially serious complications. TREATMENT will generate a precise, non-invasive nerve stimulator that uses Temporal Interference in an ultra-thin form factor (enabling patch-based applications) that will (i) target one nerve of interest and avoid off-target stimulation, (ii) avoid s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'ERA Chair for Accelerated Synthetic Chemistry Technologies at Palacký University Olomouc' in the context of a Horizon Europe call.

assistant: **Objectives**

To unite a powerful potential of two outstanding research leaders and thus capitalize on their mutual collaboration for reaching the impact none of them would achieve on their own. This is the aim of the ACCELERATOR project. It brings together (1) the world-renowned Professor of Chemistry, inventor and innovator Alexander Dmling as an ERA chair of the Synthetic Group and (2) the Czech Advanced Technology and Research Institute (CATRIN) of Palack University Olomouc (UP), merging three excellent research centres into a unique scientific ecosystem.Better links between R&I actors across European Research Area (ERA) and beyond is a must if Europe is to maximize excellence from across the continent. UP has been pursuing this goal for a long time now. To become a pocket of excellence and an advanced research trend-setter, UP needs to yet (i) enhance the excellence and strengthen its position in ERA; (ii) streamline the R&I commercialization system and establish new industrial partnerships and (iii) foster brain circulation to attract outstanding scientists.So far unconquered issue of automation in synthetic chemistry, innovative compound-based whole-plant-screening technologies for securing food supply, novel antibacterials addressing the challenge of increasing antimicrobial resistance and breakthrough materials for batteries and supercapacitors enabling energy storage from renewable sources are just few challenges awaiting to be solved by the ACCELERATOR. The project that has all prerequisites to rise the ERA Chair's expected impact to its fullness.Project will lead to (1) the increase of the UP's research excellence; (2) institutional changes at UP through strengthening the Innovation & Knowledge Transfer Ecosystem in Olomouc region; (3) improved capability of UP to success
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Smart glasses for multifacEted visual loss mitigation and chronic disEase prevention indicator for healthier, saFer, and more productive workplAce foR ageing population' in the context of a Horizon 2020 call.

assistant: **Objectives**

See Far project aims to develop and validate a digitally enabled adaptive solution supporting ageing workforce with vision loss, an age-related condition, to remain actively involved in professional life, helping them to sustain and renew their work and personal life related skills and support independent active and healthy lifestyles. The See Far solution consists of two components: (i) See Far smart glasses where the display lenses are adapted to the needs of the users and optimize their view.  In order this to be achieved a personalized visual assistant is developed capturing the condition of the eye, detecting the problem and provide the appropriate adjustment through the integration of augmented reality technologies.  See Far smart glasses empower older adults to solve the most meaningful problems, transform how they design, build, maintain and collaborate in their organization, perceive the world conveniently and enjoy a safer exploration in an indoor/outdoor environment. (ii) See Far mobile application allowing monitoring of the central vision evolution and prediction of the risk for the presence of diseases (i.e. diabetes risk, cardiovascular risk).  It will capture retinal images, through a digital direct ophthalmoscope attached in the smartphone, analyze the images (Image Analysis Component), and detect the type and the stage of vision impairment (Decision Support Component). The combination of the output of the See Far mobile application (indicator of the presence of a visual or not problem) with the output of the See Far smart glasses (type of daily visual issues the user has and his/her behavior) will lead to the provision of suggestions, through augmented reality, to the user supporting independent active and healthy lifestyles.  The suggestions will be ad
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'MuTi-modulE smArt systeM for selective electroSynthesis' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Electrosynthesis, powered by renewable energy, has the potential to remap existing industries like energy, transport, and manufacturing, by generating clean fuels and chemicals. Examples include water electrolysis to produce green hydrogen and the emerging CO2 electrolysis to synthesize important carbon chemicals such as ethylene. One challenge in these reactions is reactant and product management – gas, both as a reactant and product, brings solubility barriers (e.g., limited solubility of CO2) and strong fluctuations due to the formation of bubbles (H2 in the cathode, and O2 in the anode). Inefficient reactant supply and complex interfacial phenomena are often addressed in these systems at the atomic scale and in a static fashion (i.e., catalyst and environment design). TEAMS (MuTi-modulE smArt systeM for selective electroSynthesis) seeks to address this problem through the nano-macroscopic scale and in a dynamic way. It proposed to do so by integrating three key modules in a modular and smart, self-driven architecture: a nanobubble generator to increase gas availability, an interface reaction module to enhance efficiency and selectivity, and a feedback optimization module for continuous real-time system adjustments. TEAMS targets the application of this system into two reactions limited by gas availability and interface bubble formation, such as CO2 electrolysis into ethylene (cathode) and ethylene oxidation into ethylene oxide (anode). By combining nanobubble engineering, fluid dynamics, and electrochemical methodologies, TEAMS aims to create a next-generation, scalable, and automated electrosynthesis system.


**Keywords:** Nanobubble Engineering, Multiphysics Simulation, Smart System Engineering, Gas-liquid Interface Engineering, Power-to-X
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Extreme Particle Acceleration in Shocks: from the laboratory to astrophysics' (XPACE), addressing dissemination and exploitation.

assistant: **Impact**

Astrophysical shocks are among the most powerful particle accelerators in the Universe. Generated by violent interactions of supersonic, and often relativistic, plasma flows with the ambient medium, shock waves involve a complex and highly nonlinear interplay between the dynamics of flows, magnetic fields, and accelerated particles through mechanisms not yet fully understood. What is the origin of cosmic rays?, What controls particle injection and the acceleration efficiency in collisionless shocks?, How is the physics of relativistic shocks modified by electron-positron pair production?, Can these mechanisms be studied in the laboratory? These are long-standing scientific questions, closely tied to extreme plasma physics processes, and where the interplay between micro-instabilities and the global dynamics is critical. Advances in high-power lasers and particle beams are just now opening unique opportunities to probe the microphysics of shocks and particle acceleration in controlled laboratory experiments for the first time. Together with the fast-paced developments in fully-kinetic plasma simulations, computational power, and astronomical observations, the time is ripe to deploy a research program focused on particle acceleration in shocks that can transform our ability to address these questions. In the ERC grant XPACE, we aim to use first-principles massively parallel simulations and laboratory experiments to study the microphysics of non-relativistic and relativistic shocks, and to use data-driven techniques to develop multi-scale models that bridge the gap between the microphysics and the global dynamics. This project will build comprehensive models of the plasma processes that shape magnetic field amplification, particle acceleration, and radiation emission in sh
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Industrial Cell Factories and Sustainable Bioprocessing for Future Bioeconomy' (CelESTial) targeting Horizon 2020.

assistant: **Abstract**

Biosustainablility is an important goal for humanity as it addresses many global challenges we face. The rapidly emerging field of synthetic biology provides a powerful opportunity to make this goal a reality. By combining molecular biology and engineering, synthetic biology represents a paradigm shift where biology is becoming an engineering discipline with tools to design and construct cells and organisms with novel functions. These can be used as cell factories to replace and extend current chemical and pharmaceutical production techniques in an environmentally sustainable way. A number of cell factories developed in recent years have replaced existing production techniques because they are economically superior, but may be utilized in coming years to address global climate change.To foster the development of synthetic biology and cell factory development, we propose a Teaming partnership between the Estonian Centre for Synthetic Biology (Estonia) at the University of Tartu and the Novo Nordisk Foundation Center for Biosustainability (Denmark) at the Technical University of Denmark. We will create a research and development platform for the sustainable bio-manufacturing of high value chemicals and pharmaceuticals using cell factories. The platform, which relies on the concerted action of both centres, and their industrial partners, will accelerate the transition from proof-of-concept science to commercial production via a system of iterative cycles. This platform will move cell factory technology from the lab to pilot-scale production in bioreactors with less cost and development time compared with current state-of-the-art techniques. This project also aims to enhance regional development by extending the innovative biosustainable research and industrial practices of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Set-up and Testing of a web-intensive Collaborative Inventive TTT service with the overall goal to trigger cross-sectorial networking of stakeholders in the global market' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

IRCs pioneered Transnational Technology Transfer (TTT) in Europe. Although they embrace the TTT mission widely, core business and key results are mainly focused on SMEs. The introduction of Open Innovation paradigms by large enterprises validated this pioneering approach by EC. YET2.com was launched to exploit IPR assets from large companies. However successful TTT conclusions are still limited and require the concurrent involvement of multidisciplinary teams.The process is time consuming and resource intensive, with average unit costs for delivering a TTT agreement too high, making the process as of today not self-sustainable. D'Appolonia, in the last 15 years of experience within the European Space Agency Technology Transfer Programme, has experienced the effectiveness of proactive TTT as complement to traditional market pull and technology push approaches. Within the EC project Webtex-pert methodological insights have been gained. Tools have been developed in cooperation with DITF-MR to favour effective dynamic collaboration for inventive TTT across network of knowledge mediators.Based on this latest methodological development, main objective is to fully exploit the European excellence in TTT and available networks and initiatives as IRCs to set-up an experimental but concrete action by means of a pilot service targeting three European lead sectors, namely aerospace/security, automotive and textile as pilot areas for promising cross-sectorial TTT opportunities. The pilot audience consist of SMEs, Large enterprises, Industrial Associations and Groupings, Universities and research centres as well as technology brokers, development agencies and even individuals as beneficiaries of or sources for TTT.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'A lagrangian experiment in the Arctic vortex' under Fourth Framework.

assistant: **Concept**

Although the ozone depletion mechanism in polar areas is generally understood, 3 D model simulations of cumulative loss in the winter/spring season in the Arctic, essential for forecasting what could happen in the future, fail to capture the loss rate and thus the amplitude of the depletion. The reason for this resides in an accumulation of uncertainties such as in difference between the real atmospheric temperature compared to that simulated in the Global Circulation Models (GCM); in the nature of PSCs formed at a given temperature to which the efficiency of heterogeneous reactions is extremely sensitive; and finally in photochemical reactions and photolysis rates. The Lagrangian experiment is to perform a variety of measurements on-board 3 constant level (superpressure) and 2 vertical excursion (IR Montgolfier) long duration balloons together in the polar vortex in the winter of 1999 and to compare the results to ECMWF and UKMO analysis as well state of the art, transport, radiative transfer, microphysical and photochemical simulations. Temperature, pressure, altitude, up and down welling infrared radiation, in situ PSC, ozone and water vapour, along the trajectory of the superpressure balloons and the same plus 03, N02, OC10, BrO, CH4 and H20 profiles from the Montgolfier, will allow to address a series of mechanisms extremely difficult to study by conventional means: i)the possible temperature and wind bias in the GCM (ECMWF and UKMO) models,particularly away from radiosonde stations, on which all photochemicalsimulations are based; ii) the amplitude of the temperature fluctuation under the influence oforographic and gravity waves compared to the mean, an extremely importantpoint since the PSC formation is controlled by the lowest temperature andnot by the mean at a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Transnational networks in European environmental policy – path dependent or learning?'.

assistant: **Concept**

This research builds on the results of the initial Marie Curie project on the origins of the environmental policy of the European Communities, and extends its scope significantly up to the Maastricht Treaty. In the MC project I was able to demonstrate that – contrary to the assumptions of the traditional state-centric historiography of European integration – informal networks of actors coalesced to shape and institutionalise the new policy agenda. These networks comprised supranational and member state actors as well as non-governmental actors like the environmental movement, and scientific experts.The goal of the new project is to inquire into the longer-term role of these networks. Historical institutionalist theories suggest that the early establishment of policy networks encouraged closure and institutionalisation, leading to a path dependent development of the network and policy. The project seeks to test this hypothesis, by inquiring into factors of continuity and change affecting the policy network. External factors of change such as the impact of enlargements and institutional reforms will be examined. Factors internal to the network such as changes in composition and in attitudes will also be explored. Most importantly, the ability of the environmental policy networks to “learn” will be explored.This contemporary historical project will trace the networks initially found in three case studies – nature protection, water policy, and at the generic level of the Action Programmes. Conceptually informed by social science network analysis, for the empirical research the project relies on a variety of sources from institutional, national, and NGO archives, published materials and oral history interviews. Its dual impact will consist of its contribution to conceptual a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Calcium dependence of neurotransmitter release in a gabaergic central synapse' (1994-1998).

assistant: **Innovation**

Research objectives and content This project centers on the study of calcium-dependent release of neurotransmitter at inhibitory synapses in the molecular layer of the rat cerebellum. The cerebellar slice preparation is advantageous for performing simultaneously Cai imaging in identified neuronal processes and electrophysiological recordings from pre- and post-synaptic neurons. At basket cell-Purkinje cell synapses patch-clamp pipettes may be used to control presynaptic excitability and to introduce into presynaptic terminals substances modulating synaptic function. Using the above preparation and techniques we propose to study the role of several factors determining cerebellar inhibitory postsynaptic currents, including i) failures of action potential propagation, ii) Ca entry following presynaptic depolarization, and iii) Ca release from intracellular stores. Training content (objective, benefit and expected impact) The applicant expects to gain extensive experience in combining electrophysiological recordings from pairs of neurons and simultaneous monitoring of intracellular calcium levels with fluorescence imaging methods. The host laboratory has gained a large experience in these techniques in past years, and intends to develop them further during the planned research period. Learning these techniques should endow the applicant with the capability to reach a high technical standard in her own future research projects after returning to Italy.