RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Synergy and antagonism of cholinergic and dopaminergic systems in associative learning' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Neuromodulators such as acetylcholine and dopamine are able to rapidly reprogram neuronal information processing and dynamically change brain states. Degeneration or dysfunction of cholinergic and dopaminergic neurons can lead to neuropsychiatric conditions like schizophrenia and addiction or cognitive diseases such as Alzheimer’s. Neuromodulatory systems control overlapping cognitive processes and often have similar modes of action; therefore it is important to reveal cooperation and competition between different systems to understand their unique contributions to cognitive functions like learning, memory and attention. This is only possible by direct comparison, which necessitates monitoring multiple neuromodulatory systems under identical experimental conditions. Moreover, simultaneous recording of different neuromodulatory cell types goes beyond phenomenological description of similarities and differences by revealing the underlying correlation structure at the level of action potential timing. However, such data allowing direct comparison of neuromodulatory actions are still sparse. As a first step to bridge this gap, I propose to elucidate the unique versus complementary roles of two “classical” neuromodulatory systems, the cholinergic and dopaminergic projection system implicated in various cognitive functions including associative learning and plasticity. First, we will record optogenetically identified cholinergic and dopaminergic neurons simultaneously using chronic extracellular recording in mice undergoing classical and operant conditioning. Second, we will determine the postsynaptic impact of cholinergic and dopaminergic neurons by manipulating them both separately and simultaneously while recording consequential changes in cortical neuronal activity and le
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'effective Container inspection at BORDer control points' (C-BORD) under Horizon 2020.

assistant: **Objectives**

Efficient NII (non-intrusive inspection) of containerised freight is critical to trade and society. Freight containers are potential means for smuggling (e.g. tobacco), illegal immigration, trafficking of drugs, mis-declared goods and dangerous illicit substances, including explosives, nuclear material, chemical and biological warfare agents and radioactively contaminated goods. One inspection NII technology cannot cope with all these targets. The C-BORD Toolbox and Framework will address all these targets and enable customs to deploy comprehensive cost-effective container NII solutions to potentially protect all EU sea- and land-borders, satisfying a large range of container NII needs. The C-BORD Toolbox will include 5 complementary innovative detection technologies: delivering improved X-rays, Target Neutron Interrogation, Photofission, Sniffing and Passive Detection. User interfaces and data will be integrated to optimise effectiveness and efficiency of end-users and systems. The C-BORD Framework will help customs analyse their needs, design integrated solutions, and optimise the container inspection chain; it will address detection levels, false alarm levels, throughput, health & safety, logistics and cost & benefits.C-BORD will increase the probability of finding illicit or dangerous content with at least equal throughput of containers per time unit, reduce the need for costly, time-consuming and dangerous manual container inspections by customs officials, and in case a container is opened, increase the probability of finding illicit materials. C-BORD involves stakeholders from 8 EU countries, as partners (5) and advisory group members (3). On 3 custom sites integrated solutions will be trialled, respectively addressing the needs of big seaports, small seaports and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Cotton biomass energy recovery' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

COBER (COtton Biomass Energy Recovery) intends to join the R & D efforts of some European companies and research institutes, in order to contribute to the feasibility study of a biomass residue based, power generation system, focusing its work on the cogeneration technology. This main objective is fully consistent with the overall objective of JOULE III Third Call for proposals (Jan-97, paragraphs 3.5.A.1, 3.5.A.4 and 3.5.A.5). Within this frame, the present feasibility study is going to demonstrate on an economics and technical point of view, the potentiality of the energy production from the agricultural residues of cotton plants in South Europe. Other objectives of the COBER project are: - the qualification of innovative reverse logistics processes, systems and technologies of wide applications in line with agricultural and industrial production. - the Pilot implementation of efficient and clean combustion technology, certified for cotton biomass burning procedure. - the feasibility study for a wide commercial exploitation of the produced heat. The main expected output of the project will be the feasibility study of a power generation system of 20 MWe based on cotton biomass residues of South Europe. The evaluation will utilize published information, existing test facilities and process simulation tools to address to: - The minimisation of fuel consumption of the end-user for energy production using advanced cogeneration techniques. - The optimisation of the overall efficiency of electricity production. - The suitability of available cotton biomass feed stocks for advanced burning processes. - The improvement of life quality with the utilisation of new technologies of commercial exploitation of the produced heat like teleheating etc. - The provision of design princip
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The European Renewable Electricity Certificate Trading Project' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

1) To ensure that REC market development is coordinated, that information is shared, and that barriers to REC trade between Member States are minimoised;2) To disseminate widely, knowledge and understanding of REC market development to stakeholders and potential beneficiaries;3) Based on existing work, and coordinating carefully with existing work, to help key stakeholders in Member States to define the necessary institutional framework, criteria and principles to promote REC trade, nationally and EU-wide;4) To analyse and disseminate the costs and benefits of using RECs to purchase the environmental benefit of renewable electricity production;5) Using powerful 'hands-on' simulation and dissemination techniques, to demonstrate to key stakeholders how an EU-wide REC market could work and to help to develop consensus on how national and international trade in RECs should be archived.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Novel Quantum Emitters monolithically grown on Si, Ge and III-V substrates' (4PHOTON), addressing dissemination and exploitation.

assistant: **Impact**

We propose to forge a partnership between the leading European groups working on the next generation of solid state quantum emitters based on novel growth methods such as Droplet Epitaxy. Future, practical Nano-photonics and Quantum Circuits applications demand semiconductor quantum dots that can be grown on substrates with different lattice parameters (Si, Ge, GaAs), different substrate orientations (such as (001) and (111)) and tuneable optical, electrical and spin properties. All these requirements are met by high quality quantum dots grown with Droplet based Epitaxy techniques, circumventing the limitations of currently available systems based on strain-driven dot self-assembly. This vast novel research area at the crossroads of photonics, material science, quantum physics and nano-scale device fabrication will allow delivering top level multidisciplinary training to 15 early stage researcher (ESRs). The successful training of the ESRs by leading academic and 3 full industrial partners will be crucial for achieving the headline goals of this first ever consortium on droplet dot devices: (1) Entangled light emitting diodes with droplet dots grown on (111) substrates (2) Electrically triggered, droplet dot based single photon sources on Si/Ge substrates (3) Strain tuning in droplet dots without wetting layer: photon polarization and single spin control (4) Droplet Dot based single photon sources for non- classical light storage devices based on hybrid quantum systems (dots & laser-cooled atoms). The training and research progress will be discussed and monitored during the 4 project meetings, 3 summer schools and the final international conference on Droplet Dot Devices, all of which are open to the whole scientific community. We expect this network, based on the solid
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'High resolution Miniature Implantable nerve Stimulator for Electroceutical Research (HiMISER)' (HiMISER).

assistant: **Innovation**

In my ERC project ‘µThalys’, we are researching future concepts for electronic medical implants. The main idea is to replace current medical implants that typically consist of a titanium casing with electronics and a few lead wires with less intrusive, softer, tissue-like implants. These future generation implants consist of soft, modular, miniature transducer nodes that can act stand-alone, or be connected in a network, thus forming e.g. an implantable sensor network.  Now, the main idea driving this proof-of-concept (PoC) project application is that the results of our research could be very suitable to apply in an upcoming field that uses peripheral autonomous nerve stimulation for therapeutic ends. This is mostly referred to as ‘electroceuticals’ or ‘bioelectric medicine’. Rather than using chemical drugs that circulate through the entire body, the field of electroceuticals aims to develop therapies based on local stimulation of a nerve of the autonomous nervous system that leads to the target organ. For example, instead of taking drugs to reduce stomach acid formation the part of the vagus nerve going to the stomach can be stimulated to achieve the same therapeutic effect while reducing side-effects.  However, current nerve stimulation devices are rather crude and stimulate all fibres in a nerve using a cuff electrode. Moreover, they are too large to allow them to be used in small animal studies. The non-availability of a miniature, high-resolution peripheral nerve stimulator is therefore a significant roadblock for researchers in the field, and for the future application in humans.  In this project, we will combine our existing research results from the µThalys project to create a new generation of stimulators. Miniature electronics devices, packaging and soft high
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Next Generation of Algorithms and Software for Robust and Global Optimization of Dynamic Systems', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Engineers routinely use optimization in designing and operating engineered systems, as a means for improving their performance from an economic standpoints or in terms of their environmental impact and safety. Most rigorous optimization implementations to date have been for continuous processes using steady-state simulation and optimization, yet a wide variety of process systems either are inherently dynamic or are intentionally operated in a dynamic way. This is the case in particular for new technologies including renewable energy processes and environmental systems, whose complexity challenges the current state-of-the-art methods and tools, calling for new types ofdecision-making tools based on systematic optimization. In a society where sustainability and competitiveness are two principal drivers, optimization methods that can provide a certificate of global optimality and/or robustness to support the design and control of dynamic processesare inevitably becoming more and more important.Optimal control is the one technology that can optimize complex dynamic systems. The ROGO-DYN project focuses on the further development of optimal control theory and algorithms, with particular emphasis on (i) determining global optimal control decisions for complex dynamic systems and (ii) enforcing robustness of control decisions in uncertain environments. While the theory of nonlinear optimal control is well established and a wide variety of local optimization algorithms are nowadays available, very few rigorous global and robust optimal control algorithms have been developed to date and no generic software implementation is available. It is therefore another principal objective of ROGO-DYN to pioneer the development of open-source software implementing global and robust optimal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'heaRt failurE paTient managEment and iNTerventIOns usiNg continuous patient monitoring outside hospitals and real world data'.

assistant: **Innovation**

Heart failure (HF) is a prominent chronic disease, despite efforts in improving its prevention, diagnosis and treatment, represents the leading cause of disability and premature death throughout the world, while being is a heavy burden on health systems due to the multiple, prolonged hospitalizations required for patients suffering from it and the related management costs. Nevertheless, studies have shown that routine patient-physician or patient-nurse communication following discharge can result in significant reduction of hospitalizations. The pertinent collected patient data may include simple yet important information (e.g. patient weight), as well as previously difficult to obtain information such as routine ECG, ICD/CRT-D interrogation and pulmonary arterial pressure monitoring, which are now within reach due to technological progress. Motivated by the above, RETENTION aims to develop and deliver an innovative platform supporting enhanced clinical monitoring and interventions aimed at improving the clinical management of patients with chronic HF, reducing their mortality and hospitalisation rates, and improving their quality of life, safety, and well-being. The RETENTION platform will support clinical decision making and evidenced based personalised interventions for HF patients by: (a) continually monitoring and collecting medical, clinical, physiological, behavioural, psychosocial, and real-world data for such patients, (b) analysing these data using innovative model-driven big data analytics, statistical, artificial intelligence and machine learning techniques, (c) detecting patterns in the HF disease progression and the quality of life of patients, (d) cross checking and validating them against the clinical literature, and (e) offering transparent, explainable
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Evolution of Development In Plants' in the context of a Seventh Framework call.

assistant: **Objectives**

Different morphologies evolve in different organisms in response to changing environments. As land plants evolved, developmental mechanisms were either generated de novo, or were recruited from existing toolkits and adapted to facilitate changes in form. Some of these changes occurred once, others on multiple occasions, and others were gained and then subsequently lost in a subset of lineages. Why have certain forms survived and others not? Why does a fern look different from a flowering plant, and why should developmental biologists care? By determining how many different ways there are to generate a particular morphology, we gain an understanding of whether a particular transition is constrained. This basic information allows an assessment of the extent to which genetic variation can modify developmental mechanisms and an indication of the degree of developmental plasticity that is possible and/or tolerated both within and between species. This proposal aims to characterize the developmental mechanisms that underpin the diverse shoot forms seen in extant plant species. The main goal is to compare developmental mechanisms that operate in vegetative shoots of bryophytes, lycophytes, ferns and angiosperms, with a view to understanding the constraints that limit morphological variation. Specifically, we will investigate the developmental basis of three major innovations that altered the morphology of vegetative shoots during land plant evolution: 1) formation of a multi-cellular embryo; 2) organization of apical growth centres and 3) patterning of leaves in distinct spatial arrangements along the shoot. To facilitate progress we also aim to develop transgenic methods, create mutant populations and generate digital transcriptomes for  model  species at key phylogenetic nod
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Neuroprotection and natural history in parkinson plus syndromes: a clinical trial of the efficacy and safety of riluzole in parkinson plus syndromes' (NNIPPS).

assistant: **Innovation**

The Parkinson-Plus syndromes, Multiple System Atrophy and Progressive Supranuclear Palsy (MSA & PSP) are rapidly progressive neurodegenerative diseases, leading to severe disability and death. They are orphan diseases with neither symptomatic nor curative therapy. We will(i) establish whether the antiexcitotoxic drugriluzole can slow the disease progression,(ii) provide for the first time prospective data on their natural history. In U. K., France, and Germany, 800patients, stratified on MSA or PSP, will randomly be assigned to placebo orriluzole and followed double blind for 36 months. The primary efficacy criterionis survival.The project will validate diagnostic staging, new assessment instruments and disease severity staging;assess cognitive function, quality of life and health economics;and establish DNA and tissue banks for basic research.The project will comply with the GMP, GCP, GLP and GSP specifications.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Measuring Convergence and Divergence in Varieties of Chinese: A Lectometric Approach' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

What can Chinese teach us about the languages of Europe? Sociolinguistic research has obtained important insights into the dynamics of the languages of Europe: the emergence of pluricentric varieties, the global influence of English, the tendency towards informalization of the standard languages. But are these phenomena typically European, or are the same forces at work in other linguistic areas? A comparison with Chinese may provide an answer: I will analyze three varieties of Chinese (mainland China, Taiwan, Singapore) from the same perspectives that have been applied to the convergences and divergences of European languages, and with the same (quantitative, so-called ‘lectometric’) methods. Getting to know these methods better will be how I will benefit from the project. Conversely, the data that I will be able to obtain for the current evolution of Chinese will deepen the understanding of the European tendencies. For instance, does the size of the languages involved play a role, or the kind of language policies at work in the different countries? In practice, the project intends: 1) to evaluate lectometric measurements that have been recently developed for studying changes in the position of standard languages in Europe and offer a methodological guideline with which lexical variation among lects can be structured more comprehensively and cost-efficiently; 2) to identify the multifactorial variational structure that underlies the Chinese lexicon in written texts (synchronically); 3) to uncover how the stratificational distances among lects are changing progressively (diachronically) and to confront with what we find for Chinese and what we know about the processes in Europe. The project targets academics as well as policy makers. It will provide new insights into th