RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Nitride-based nanostructured novel thermoelectric thin-film materials' to be submitted under Seventh Framework.

assistant: **Abstract**

My recent discovery of the anomalously high thermoelectric power factor of ScN thin films demonstrates that unexpected thermoelectric materials can be found among the early transition-metal and rare-earth nitrides. Corroborated by first-principles calculations, we have well-founded hypotheses that these properties stem from nitrogen vacancies, dopants, and alloying, which introduce controllable sharp features with a large slope at the Fermi level, causing a drastically increased Seebeck coefficient. In-depth fundamental studies are needed to enable property tuning and materials design in these systems, to timely exploit my discovery and break new ground.The project concerns fundamental, primarily experimental, studies on scandium nitride-based and related single-phase and nanostructured films. The overall goal is to understand the complex correlations between electronic, thermal and thermoelectric properties and structural features such as layering, orientation, epitaxy, dopants and lattice defects. Ab initio calculations of band structures, mixing thermodynamics, and properties are integrated with the experimental activities. Novel mechanisms are proposed for drastic reduction of the thermal conductivity with retained high power factor. This will be realized by intentionally introduced secondary phases and artificial nanolaminates; the layering causing discontinuities in the phonon distribution and thus reducing thermal conductivity.My expertise in thin-film processing and advanced materials characterization places me in a unique position to pursue this novel high-gain approach to thermoelectrics, and an ERC starting grant will be essential in achieving critical mass and consolidating an internationally leading research platform. The scientific impact and vision is in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Planning and research of policies for land use and transport for increasing urban sustainability' (PROPOLIS) targeting Fifth Framework.

assistant: **Abstract**

Problems to be solved More than three-quarters of the population of Western Europe live in cities. Their quality of life, health as well as safety are to a considerable extent affected by the environmental quality, provision of and access to services, and safety of their home cities. Part of the economic efficiency of urban regions is lost due to urban congestion and pollution. Methodologies are needed for predicting and mitigating negative changes and for bringing about positive ones. PROPOLIS project addresses these issues by enabling the prediction of the impacts of urban transport and land use policies. The problems of growing traffic and the sprawl of urban areas together with the associated adverse environmental, social and economic impacts are experienced everywhere in Europe. Therefore, accumulating know-how, developing methodologies and searching for sustainable urban policies is no doubt of strategic importance and a field meriting a European-wide approach and concentration of know-how and resources. ROPOLIS contributes to the implementation of many of the EU's policies, especially environment, energy and transport. It also addresses questions of European wide interest and of strategic importance. Scientific objectives and approach The objective of PROPOLIS is to research, develop and test integrated land use and transport policies, tools and comprehensive assessment methodologies in order to define sustainable long-term urban strategies and to demonstrate their effects in European cities. The work is executed through developing a set of indicators measuring the environmental, social and economic components of sustainability. Values for these indicators are calculated using enhanced urban land use and transport models and new GIS and Internet based modules. A
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Innovation in modelling Placenta for Maternal and Fetal Health' (2014-2020) under Horizon 2020.

assistant: **Objectives**

“The placenta is the least understood human organ but arguably one of the most important”-NIH Human Placenta Project .   Innovation in Modelling Placenta for Maternal and Fetal Health (iPLACENTA) is a European Training Network (ETN), and will act as a springboard for promoting international, intersectoral and multi/inter-disciplinary training, career development and collaboration of fifteen early-stage researchers (ESRs) in Maternal and Fetal Health.  iPLACENTA will improve our ability to study, model and visualise the placenta.   iPLACENTA focuses on doctoral-level training and will be delivered by eleven participating universities located in ten different European countries. It coordinates research and training collaboration among world-leading academic institutions in Europe, providing a new combination of in-depth international expertise. iPLACENTA’s unique network aims are to improve our ability to study the placenta through in vitro and mathematical modelling (WP1&2).  Whilst enhancing visualisation and assessment of the placenta in animal models and the clinic, thus enhancing investigation and prognosis of complicated pregnancies. To link the research to industrial exploitation, the network brings together three different businesses; Mimetas (MIM) (organ-on-a-chip developer) as a beneficiary, and Moor, a clinical-technology specialist, and industrial global brand FujifFilm VisualSonics (FUJ) as partners. Together they will work with academics and clinicians to develop new placenta-on-a-chip technology (WP1), in silico placenta modelling (WP2), new modalities of laser technology to visualise the placenta in vivo (WP3), improve maternal-cardiovascular assessment and validate novel ultrasound tools for diagnosis of complicated pregnancies (WP3). Cross-sectorial trai
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Development of advanced control methodologies using reliable multidetection sensors for boilers' (1994-1998) under Fourth Framework.

assistant: **Objectives**

The ACORDE system produced consists of an expert system that was built in the project in a open configuration, allowing the final users to programme rules to be tested continuously with plant data. A conditional monitoring system is used to visualise the raw data and can also be used by the user for a first assessment. Sample rules for NOx emissions and efficiency were prepared and they issue qualitative recommendations to the operator. In some of them the user is informed that a quantification can be made using numerical models that can be used by the operator with current plant data. Simulations can be done to analyse the effect of air distribution in the NOx emissions and to analyse the effect of cleaning heat transfer surfaces in the boiler efficiency. The user may also perform dynamic boiler simulations.Objectives and content The aim of this project is lo develop an advanced control methodology using reliable multi-detection sensors. The developed methodology will be applied lo a boiler from the electricity production sector leading to a reduction of energy consumption, reduction of pollutant emissions, minimizalion of slagging and degradation of the tubes, increase of life cycle of envolved equipment and the flexibility of the system. In order to demonstrate the generality of the developed methodology, a feasibility study will be performed in order to assess the application of the methodology to the petrochemical industry and to waste incineration. An ON-LINE computer system which obtains information from a case-study boiler and searches for optimized operating conditions will be developed. The computer system will also be used as a training tool for plant operators and managers on the basis of analysis of alternatives and the generation of appropriate recommendat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Validation of Advanced, Collaborative Robotics for Industrial Applications'.

assistant: **Objectives**

The VALERI project proposes the development and validation of a mobile manipulator for assisting human workers in aerospace production tasks. The current production can be characterized as having large parts stationary in a production cell, whereby multiple shifts of workers complete the assembly and inspection tasks over a period of days. In such a production environment, specialized, stationary robotic systems are not economical. The employment of mobile manipulators is a way to make the use of robots more economical, by allowing for one robot to be used for similar tasks in multiple stations.The project begins by addressing the technical hurdles that currently impede the widespread use of mobile manipulators in production. Advances in vision technology for delivering a wide range of information relating both to external parts (e.g. inspection) as well as about the internal condition of the robot (e.g. pose information for navigation and path-planning) are necessary to achieve the project goals and will be developed in the project. The implementation of truly mobile manipulation algorithms for application in the production environment will be addressed as well. In addition, it is essential to address both the issues of safety and human-robot-interaction. Novel safety strategies and components offer a clear added-value to the mobile manipulator by empowering the human co-workers to collaborate and work directly with the mobile manipulator.The project aims to carry out two exemplary tasks for the end-users, namely carrying out inspections on large surfaces (e.g. turbine covering elements) and applying sealant along a groove. These tasks are carried out in variations at virtually all assembly stations, so that the system will be highly productive. Viewed abstractly, thes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Elucidating therapeutic effects and mode of action of future trophic factors in ALS and Parkinson’s disease' in the context of a Horizon 2020 call.

assistant: **Objectives**

The prevalence of neurodegenerative diseases such as Parkinson’s disease (PD) and amyotrophic lateral sclerosis (ALS) is growing rapidly due to an aging population and increased life expectancy. Current treatments for ALS and PD only relieve symptoms and cannot stop the progression of the disease, thus there is an urgent need for new therapies. Neurotrophic factors (NTFs) are secretary proteins that regulate the survival of neurons, neurite growth and branching. They have been explored as novel drugs for the treatment of ALS and PD but their efficacy in clinical trials is poor. CDNF is a protein with NTF properties that protects and restores the function of dopamine neurons in rodent and rhesus monkey toxin models of PD more effectively than other NTFs. CDNF is currently in phase 1/2 clinical trials on PD patients. Despite promising results with CDNF in animal models of PD, NTF and CDNF-based treatments have drawbacks. CDNF requires direct delivery to the brain through invasive surgery since, it cannot pass through the blood brain barrier (BBB).  My recent discovery, however, may overcome this difficulty: I showed that a novel CDNF variant protects DA neurons in vitro and in vivo and that it efficiently enters DA neurons in culture. Furthermore, my data show the CDNF fragment can pass through the BBB as measured by 3 different methods and has a neurorestorative effect in a 6-OHDA toxin model of PD when administered subcutaneously. The ultimate goal of my research is to understand the mode of action and therapeutic effect of novel BBB penetrating CDNF-derived polypeptides in cultures of human induced pluripotent stem (iPS) cell-derived nerve cells from patients and in animal models of ALS and PD. The innovative aspect of this proposal is the new groundbreaking concept fo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The significance of economic incentives in fisheries management under the CFP.' under Fourth Framework.

assistant: **Concept**

The project will examine the implementation at the national level of those key policy components of the CFP, which are intended to control fishing effort and fishing mortality. The focus of the project will therefore be on the measures adopted by different Member States in order to fulfil their obligations under the basic conservation and management regulation relating to the observance of national catch quotas and to achieve the reductions in fleet capacity agreed under the MAGPsThe focus is put on the subsequent types of management:1. Quota management systems (output regulation)2. Effort management systems (input regulation)3. Fleet capacity adjustment Economic Incentives, definitionEconomic incentives can be used by managing authorities (principals) to induce particular responses or behaviours from investors or actors (agents) in the fishing industry, either by reducing profits (in the case of negative incentives) or by increasing profits (in the case of positive incentives). When trying to determine the minimum value of the premium which should be paid from the principal (managers) to the agent (fisherman) to switch from one target species to the other, for example, fisheries managers are faced with an optimisation problem with a number of economic constraints. Problems like this can be handled using available software (such as GAMS used by several project partners). QuantificationEconomic incentives materialised in the shadow value of circumventing or violating specific management stipulations will be quantified wherever possible. This will happen along the lines explained in the above optimisation problem, once we have identified where, when and how economic incentives are implemented through existing management schemes. Hereafter, quantification could take variou
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'High Performance Power Electronics Integrations' (HiPE), addressing dissemination and exploitation.

assistant: **Impact**

HiPE brings together 13 participants covering the whole value chain, to develop a new highly energy-efficient, cost-effective, modular, compact and integrated wide bandgap (WBG) power electronics solutions for the next generation of battery electric vehicles (BEV), and to facilitate a significant market penetration of WBG in the automotive sector.The project outputs will include: i) a scalable and modular family of WBG-based traction inverters and DC/DC converters with significantly improved specific cooling performance, suitable for 400V, 800V and 1200V applications, with power ratings from 50 to 250 kW, integrated into electric drives enabling drastic size and weight reductions; ii) a family of integrated WBG-based on-board chargers and DC/DC converters, with optimised innovative topologies, including use of GaN; and iii) integrated, fault-tolerant and cost-effective GaN-based power electronics for high-voltage ancillaries and chassis actuators. The result will be an unprecedented level of functional integration, e.g., the HiPE power electronics solutions will be smart cyber-physical systems, incl. intelligent and predictive controllers to optimise performance, innovative and computationally efficient data-driven approaches to monitor the state-of-health of the relevant hardware, as well as novel digital-twin-based methodologies to tailor the component- and vehicle-level algorithms to the specific condition of the hardware installed on each individual BEV, and actively control the reliability and availability of the relevant parts. This will be achieved while preserving the expected automotive quality level without having to recur to overengineering, thanks to the innovative implementation of data-driven dependability techniques for cyber-physical systems. The extensi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Deconstructing the past: Modelling the locomotion of Miocene hominoids through computational techniques' to be submitted under Horizon 2020.

assistant: **Abstract**

The challenge of better knowing the complex relationship between bone's morphology and function has yielded tens of articles since the beginning of the last century and is essential for making positional behavioural inferences on fossil taxa. Despite its relevance, the form-function relationship is still poorly understood. Based on this premise, this project focuses on deciphering the functional loading environment and its influence on skeletal design in the hindlimb of living primates and shedding light on the locomotor evolution of fossil apes and early hominins. The fossil apes included in this project constitute key taxa for understanding the positional behaviour evolution within the Hominoidea (the apes and humans clade), which has important implications for a better knowledge of the evolutionary pathway that led to the specialized locomotor types of extant apes and humans (specialized antipronograde behaviours such as below-branch suspension and human terrestrial bipedalism). To accomplish the aims, this project will rely on diverse, multidisciplinary and innovative techniques, including biomechanical and engineering approaches (e.g., multibody dynamics analysis, computer optimization, machine learning and data science), phylogenetic comparative methods, and collection of experimental data (e.g., recording of live primates kinematics). This project also involves an important component of training for the applicant and several short stays to gain a diversified and unique set of skills and knowledge on the field of paleoprimatology and evolutionary biology. Hence, this project will extend our knowledge on the bone's form-function relationship, as well as the origin, tempo and mode of the hominoids positional behaviour evolution, including key long-lasting questions
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Functions of Genomic Hypomethylation in Gametogenesis'.

assistant: **Innovation**

Replication in S phase duplicates not only the genome but also the epigenome, to ensure cell identity is propagated and genome stability maintained in daughter cells. Epigenome propagation in development has been understudied due to lack of appropriate methods, even though replication is widely accepted to be a primary vehicle through which programmed epigenetic changes occur in vivo. In mammalian germline development, the epigenome is reprogrammed via impairment of the epigenome maintenance network. By dividing without maintaining core components of the epigenome, primordial germ cells harbor genomes devoid of the crucial repressive mark DNA methylation. Hypomethylation is destabilizing because it de-represses transposable elements. Despite this, oocytes arrest in a hypomethylated state, regaining methylation only in preparation for ovulation as part of puberty. In parallel, two-thirds of the oocyte pool dies around birth in mammals, and the features delineating oocytes that survive this process from those that die are unclear. I propose that hypomethylation is alternately selected for and against across gametogenesis. Specifically, that hypomethylation a positive feature in primordial germ cells but a deleterious feature in the female germline after sex specification. To test this, we will develop novel transgenic mouse models and technologies to study epigenome propagation in vivo, and utilize state-of-the-art sequencing, mass spectrometry, microscopy, and metabolic labelling approaches. By developing a method for tracking DNA molecules and their associated methyl marks across division in live animals and embryos, we will establish an unprecedented technology for understanding epigenome propagation in development. Cumulatively, this work will uncover the functions an