RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Diversity, stability and functioning of the soil microbiome'.

assistant: **Objectives**

A major challenge for advancing our understanding of the functional role of highly complex soil microbial communities is to systematically link changes in their structure and functioning to biogeochemical cycles under realistic scenarios of global change. This is a formidable challenge: not only does it require a step change in our understanding of the factors that shape soil microbial communities and their functioning, but also it requires new knowledge of the ecological and genetic mechanisms that underpin its stability, or ability to resist and recover from abiotic perturbations associated with global change. By embracing technological and theoretical developments in microbial ecology, SoilResist will make a major step forward in our understanding of the mechanisms that underpin the resistance and resilience of soil microbial communities and their functioning to natural and anthropogenic perturbations. Specifically, I seek to develop a novel mechanistic understanding of the factors that underpin the resistance and resilience of complex soil microbial communities and their functioning to different types of anthropogenic perturbations, and, for the first time, identity critical thresholds for abrupt transitions of microbial communities to alternative states and consequences for soil functioning. My overarching hypothesis is that the stability of microbial functions, in terms of their capacity to resist and recover from a pulse perturbation caused by climate extremes, is determined by microbial functional diversity, based on range and relative abundance of microbial traits. I also hypothesize that shifts in microbial functional diversity resulting from press perturbations erode the capacity of soil microbial communities to buffer climate-related pulse perturbations, ren
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Monitoring Atmospheric Composition and Climate Interim Implementation'.

assistant: **Objectives**

MACC II (Monitoring Atmospheric Composition and Climate – Interim Implementation) is designed to meet the requirements that have been expressed for prototype operational GMES services for the atmospheric domain. From late-2011 MACC II will continue the operation and development of the GMES service lines established by the MACC project and prepare for its transition in 2014 to become the atmospheric monitoring component of GMES Operations. MACC II will prepare for full operations in terms of continuity, sustainability and availability. It will maintain and further develop the efficiency and resilience of its end-to-end processing system, and will refine the quality of the products of the system. It will adapt the system to make use of observations from new satellites, in particular the first of the atmospheric Sentinels, and will interface with FP7 RTD projects that contribute towards long-term service improvement. MACC II will ensure that its service lines best meet both the requirements of downstream-service providers and end users, and the requirements of the global scientific user community. The service lines will cover air quality, climate forcing, stratospheric ozone and solar radiation. MACC II will deliver products and information that support the establishment and implementation of European policy and wider international programmes. It will acquire and assimilate observational data to provide sustained real-time and retrospective global monitoring of greenhouse gases, aerosols and reactive gases such as tropospheric ozone and nitrogen dioxide. It will provide daily global forecasts of atmospheric composition, detailed air-quality forecasts and assessments for Europe, and key information on long range transport of atmospheric pollutants. It will provide comprehen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Prevention of zoonotic tissue cyst formation in sheep using live attenuated and parapoxvirus vector based vaccines against Toxoplasma gondii' under Seventh Framework.

assistant: **Concept**

Toxoplasmosis is among the most important foodborne infections worldwide. In the EU, most human infections are due to consumption of meat containing Toxoplasma gondii tissue cysts. Prevalence of Toxoplasma is higher in outdoor reared animals, such as sheep, than in animals reared indoors, and consumer interest in animal welfare and free-range meat production may contribute to a further increase in the prevalence of Toxoplasma unless control measures are implemented. Vaccination of consumption animals to prevent Toxoplasma infection and tissue cyst formation could be highly effective in reducing the disease burden in humans. The only commercially available vaccine against toxoplasmosis in sheep, Toxovax, prevents congenital disease in lambs but the effect of vaccination on tissue cyst development has not been studied. Toxovax uses a live attenuated strain of T. gondii and there may be a risk of the vaccine strain reverting back to wild-type and causing disease in animals or humans. We propose to develop a safer vaccine strategy based on a recombinant parapox-virus expressing Toxoplasma antigens (TOXPOX). We will compare efficacy of TOXPOX and Toxovax in the induction of a protective immune response and the prevention of tissue cyst development using advanced immunological and molecular methods which reduce the need for use of experimental animals. A safe vaccine effective in preventing the formation of zoonotic tissue cysts in sheep is our ultimate goal. The specialized laboratory and animal facilities at Moredun and the host expertise in parasitology, virology and immunology provide the best possible infrastructure and mentoring environment to bring this project to a success. Working on this multidisciplinary project in combination with complementary skills training off
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Integrating Foresight in Research Infrastructure Policy Formulation'.

assistant: **Innovation**

The overall objective of the project is a two-fold one(i) to run a Scenario Workshop in given RI area as a preparatory step for introducing Foresight in RIs policy formulation, and(ii) to scope foresight guidelines to support prospective future foresight initiatives targeting the RI domain.Specific project objectives: to pilot a foresight exercise including the organization of a Success Scenario Workshop in the Food, Agriculture and Biotechnology area of RIs as a pilot area and the development of 3-4 contrasting scenarios; to elaborate policy recommendations for more extensive use of Foresight in RIs; to develop guidelines for scoping further foresight studies.The project runs through the following three stages:Stage 1: Data collection and assessment of key drivers in the exemplar RI area - collecting existing data on the selected RI domain, identification of key trends and issues, and assessment and prioritisation of key drivers.Stage 2: Running a Success Scenario Workshop in the pilot RI domain with the objective to come up with a feasible success scenario of 10 years ahead along with a basic policy roadmap. Prior to the workshop baseline scenarios will be prepared as to serve as a starting point of the workshop.Stage 3: Development of Guidelines to Foresight in RIs. This incorporates elaboration of draft policy recommendations for more extensive use of Foresight in this area and elaboration of a Guide to Foresight in RIs oriented towards shaping integrated RIs of European significance.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Household Chemicals Amplifying Urban Aerosol Pollution' (CHANEL) under Horizon Europe.

assistant: **Objectives**

Urban aerosol particles are one of the largest human health hazards globally. A significant fraction of urban aerosol is secondary, .i.e., formed via atmospheric chemical reactions of emitted trace gases, with secondary organic aerosol (SOA) driving health impacts in urban air. Decades of air quality regulations have substantially reduced the motor vehicle emissions of organic compounds that act as precursors to SOA pollution. In my recent studies, we show for the first time that volatile chemical products (VCPs) from household chemicals are becoming one of the largest sources of organic vapors in US cities. Based on their chemical properties, the potential of VCPs to form SOA is expected to be high but is as yet unknown. With chemical transport models showing a general shortfall in predicting urban SOA, VCPs are anticipated to be the missing source to bridge this long-standing knowledge gap. The aim of CHANEL is to provide unprecedented data to resolve the urban SOA pollution puzzle and identify the key VCP precursors to aerosol pollution. Using recent advances in state-of-the-art chemical ionization mass spectrometry, we will perform field measurements in European urban areas to determine the chemical composition of VCP emissions. A Zeppelin will be used as an airborne platform to probe the urban breath of European cities and quantify the chemical evolution and SOA production from VCPs downwind of urban centers. These measurements will be accompanied by controlled atmospheric simulation chamber experiments to oxidize VCP emissions and retrieve their SOA yields as a parametrization to be used by chemical transport models. In a future of electrified fleets where fossil fuel emissions are expected to further decrease and VCPs will dominate urban air pollution, CHANEL wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Support services to IMProve innovation and competitiveness of business in Lombardia and Emilia-Romagna' to be submitted under Horizon 2020.

assistant: **Abstract**

The objective of the present action is the establishment and delivery of a specific Enterprise Europe Network service designed to enhance the innovation management capacity of SMEs, by providing in-depth support in the areas where these services are absent or unaffordable on local markets. The service will also aim at supporting beneficiaries of the SME Instrument (H2020) dealing with coaching assignments and addressing specific innovation weaknesses.


**Keywords:** Innovation, technology transfer, coaching, KAM, SME instrument
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project '3D templating of ultrasmall metallic nanoparticles by porous columnar liquid crystals' (TEMPL3D).

assistant: **Concept**

The emergence of 3D printing technology has revolutionized the field of Liquid Crystal Networks (LCNs), enabling the fabrication of advanced functional materials with unprecedented precision and customization. However, to date, only a few liquid crystal phases (primarily nematic) have been utilized in the 3D printing of structures, thereby limiting the potential of other mesophases in more effectively controlling the anisotropic properties of the final materials. TEMPL3D seeks to overcome this limitation by combining 3D printing technology with the unidirectional order of Columnar Liquid Crystals (CLCs), pioneering a novel 3D patterning method for ultrasmall nanoparticles (USNPs). This approach aims to enhance the intrinsic properties of USNPs along the columnar axis, and potentially introduce entirely new functionalities. By leveraging the unique characteristics of CLCs and the precision of 3D printing, the research intends to develop highly ordered nanoporous polymeric materials with customizable nanopores. These nanopores will act as templates for metallic USNPs, such as superparamagnetic nanoparticles and quantum dots, enhancing or creating new properties.The ultimate goal of TEMPL3D is to develop multifunctional materials with applications in photonics, optoelectronics, soft robotics, and catalysis—surpassing current technological capabilities. This multidisciplinary project is aligned with the MSCA strategy, contributing to Europe’s growth and competitiveness.TEMPL3D also involves a strong exchange of knowledge between the host institution and me. This fellowship will play a key role in advancing my future independent research career in chemistry by offering interdisciplinary training across a wide range of skills, mentorship from leading experts in the field, and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Hydrothermal synthesis of ThermoElectric Chalcogenide-based Nanocomposites'.

assistant: **Innovation**

Thermoelectric modules enable the direct conversion of waste heat into electrical power and could therefore represent a powerful in the energy transition and the move towards a more sustainable society, if we can find efficient and non-toxic materials scalable at the industrial level. The host team has recently developed two promising families of materials, namely p-type BiCuSeO-based and n-type AgBiCh2-based materials, which are among the best lead-free materials in their temperature range. Further improvements of their performances would pave the way towards applications. In the past few years, nanostructuration has revealed itself a powerful tool for the enhancement of the thermoelectric materials performances. In that framework, the use of this technique to improve the performances of BiCuSeO-based and AgBiCh2-based materials appears appealing.Therefore, the main goal of this project is to use hydrothermal chemistry, an easily scalable synthesis process, in order to synthesize bulk pellets of BiCuSeO/graphene and AgBiCh2/graphene nanocomposites, with improved thermoelectric performances. Besides its scalable character, the use of hydrothermal synthesis has many advantages, including a very fine control of the materials size, morphology and composition. Besides synthesis, the project will include a precise characterization of the chemical composition, crystal structure and microstructure of the materials, as well as an optimization of their thermoelectric performances.Besides scientific research, several outreach activities will be implemented in order to make thermoelectricity better known by the public, including the design of demonstration kits that will be made freely available.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Rational Design and Construction of Viral Based Products' (SynVaccine) under Horizon 2020.

assistant: **Objectives**

In order to be fully effective as an oncolytic virus or vaccine, achieving of precise and specific traits are pivotal. However, current technologies are limited to the confines of a virus’s existing biological make-up. They are left with manipulation of genes within the virus e.g. deleting and adding proteins, inability to manipulate silent codes etc. where achievement of such precision is simply not possible from such naturally-rooted manipulation.The SynVaccine solution taps into 3 billion years of viral evolutionary data which is continually updated, ensuring the highest degree of accuracy on rules that govern all viruses found today. Through this, it becomes the only solution to govern the rules of viruses on a cellular level, giving the important ability to precisely dictate the traits and behaviour of the newly designed, bottom-up, created viruses. As a result, only the most effective oncolytic viruses and vaccines are ever produced, ensuring the highest levels of treatment and immunity.We have invested over €3.1 million into the development and testing of our solution to ensure its robustness and efficiency, and thus move into the next stage of specific drug development. Our management and scientific leadership capacity involves 10 multi-disciplinary experts in the fields of; entrepreneurship, virology, synthetic biology, computational biology, engineering and automation.The proposed work in Phase 1 of the SME instrument fits into our overall plan to reach the market by contributing the financial resources needed to plan a fast sound wider deployment of our SynVaccine derived solutions, and their market uptake.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Systematic identification of (p)ppGpp-dependent multidrug and stress tolerance factors' under Horizon 2020.

assistant: **Concept**

As a global healthcare issue, chronic and recurrent infections are often caused by multidrug tolerant persister cells, which are regulated by redundant pathways involving the almost ubiquitous alarmone (p)ppGpp. Despite extensive studies, two major questions in the persistence field remain to be answered, 1) the extent to which (p)ppGpp is involved in persistence and 2) how persistent cells resuscitate. To address these questions, three state-of-the-art techniques will be used in this project. First, DRaCALA (differential radial capillary action of ligand assay) will be used to systematically screen for proteins directly binding (p)ppGpp for the first time. The potential fellow from the Imperial College London has tremendous experience in DRaCALA. Second, barcode analysis by sequencing (Bar-seq) technique will be used to screen for persistence-specific and, for the first time, also resuscitation-specific genes. Collaboration with the partner Professor Duncan Maskel at the University of Cambridge, UK, a specialist in quantitative DNA deep sequencing, will ensure smooth progress of this objective and enable the potential fellow to be trained with this first-class technique. Both DRaCALA and Bar-seq will be transferred to the host lab. At last, identified candidate genes and proteins through the first two objectives will be validated with the contemporary single cell persistence assay developed in the host Professor Kenn Gerdes’s lab, at the University of Copenhagen, Denmark. Bar-seq and single cell persistence assay will be transferred to the potential fellow by senior postdocs in the partner and host labs, respectively. The tripartite cooperation with complementary expertise on a timely important project is expected to generate significant amount of high-quality data for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'LiveWire – Identifying the conductive molecules for long-distance electron transfer in cable bacteria'.

assistant: **Objectives**

Cable bacteria are multicellular filamentous bacteria found in surface sediments worldwide. They contain highly conductive periplasmic fibers (PCF) and use these fibers for intercellular long-distance electron transfer. The cells in the filament separate their energy metabolism, with most cells buried in anoxic sediment oxidizing sulfide, while a few cells at the surface use the resulting electrons for oxygen reduction. Cable bacteria significantly impact sediment geochemistry, affecting pH, ion mobility, sulfide release, and methane emissions. While their environmental interactions are well understood, the molecular principles for intercellular electron transport are still unclear. It is known that the conductivity of PCF exceeds that of any other biological material and that the PCF contains nickel, likely in the form of a novel nickel-sulfur cofactor but their protein composition was not identified. My research focus is to unravel the PCF composition and structure, as well as to identify proteins that mediate electron transfer to/from the PCF. I will combine four parallel experimental approaches: metalloproteomics, Cryo-EM, isotope labeling/NanoSIMS, and immunolocalization to study proteins in cell fractionations and in situ in intact cable bacteria. Identifying the highly effective nickel-based bioconductor and its interacting proteins is significant for understanding long-distance electron transfer and the division of labor in these multicellular prokaryotes. Revealing the PCF structure has potential applications for designing fiber polymers, conductive biomaterials, and biodegradable electronics. Through the interdisciplinary approach of LiveWire, I will expand my scientific expertise in biochemistry, structural biology, and cell imaging under the supervision of l