RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Smart Markets via Computation' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

E-commerce, modern-day government auctions, the sharing economy – these all have in common the optimization of resource allocation through the combination of economics and computation. This trend holds enormous socio-economic opportunity: for example, it allows online auctions, personalized advertising that supports the internet ecosystem, government repacking of radio spectrum to support growing communication needs, and flexible pricing that reflects true demand. It also poses an enormous challenge due to the sophisticated treatment of resources it requires, a challenge which theoretical computer science and algorithmic game theory in particular are uniquely positioned to address. Economists have known for decades that when resource allocation involves complex constraints or preferences, there will be market failures and failed auctions. At the heart of these failures is the presence of complements, which occur when economically-efficient allocation of one resource depends on that of another; in mathematical language this can be described as lack of convexity. Remarkably, this economic phenomenon is closely linked to hardness of computation, which has been extensively studied in theoretical computer science for the past 50 years.The goal of this interdisciplinary research program is to apply the theoretical understanding of non-convexity achieved in computer science, coupled with the flexibility provided by computational markets, in order to design smarter economic mechanisms. As increasingly more resource allocation in our society takes place by interaction with computational mechanisms, a unified computational and economic approach is necessary to prevent market failures and enable the full realization of the potential to boost social welfare.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Smart software platform for the economic and sustainable exploitation of dimension stone quarries' (QUARRYSMART).

assistant: **Innovation**

With a steady growth and more than 140million tons of material traded yearly, the dimension stone sector represents today a dynamic industry, with the opening and development of new quarries in many countries, from Europe to the BRICS countries and others in Africa and the Far East. This growth of dimension stone quarries has raised attention to the natural resources and land degradation of mining activities often wild, non-economic and poorly managed.A solution to this problem has been developed by us, two innovative Italian SMEs, ECO-TER and TerreLogiche. ECO-TER, is an engineering and services company working on environmental issues, geology, work health, safety and design in the areas of infrastructure projects and plant engineering works. ECO-TER provides to their clients specialized services in environmental and geological impact monitoring, studies and risk assessment, completing those activities with the development of technical and organizational solutions to be implemented during design and production phase. TerreLogiche is a company founded by personnel with 20+ years in high-tech solutions for administration, research institutes and professionals in the field of environmental monitoring, Geographic Information System and training. Working closely together, we have been developing QUARRYSMART: a reliable, practical and easy-to-use software platform to support dimension stone companies in the pre-evaluation of quarrying costs and to assist them in turning their operations into sustainable, manageable and profitable extractive units, hence attracting investments while minimizing impacts on social, ecological and environmental systems.With this project, our companies have partnered to consolidate their position in the environment sector while extending their bus
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'The role of Polycomb genes in normal stem cell and breast cancer stem cell self-renewal and maintenance'.

assistant: **Objectives**

Breast cancer is the most common malignancy of women in developed nations. Approximately 1 in 9 women will be diagnosed with breast cancer and many will receive chemotherapy and achieve long-term cancer control. However, in approximately one-third of these women, cancer will recur. This is thought to be due to the presence of chemotherapy-resistant ‘breast cancer stem cells’. Two Polycomb-group proteins, Bmi1 and Ezh2, are frequently over-expressed in breast cancer, suggesting that these epigenetic regulators may play a role in breast tumorigenesis. Interestingly, Bmi1 and Ezh2 are also known to be involved in the maintenance of adult stem cells and in normal mammary gland development. Based on these observations, we postulate that Ezh2 and Bmi1 are critical for maintaining mammary stem cell identity and that mutations leading to the continuous expression of these Polycomb-group genes contribute to the generation of breast cancer stem cells. This project will study the parallels between the role of Polycomb genes in normal mammary stem cell maintenance and their role in breast cancer. We will use novel transgenic mice that express doxycycline-regulatable short hairpin (sh)RNAs to Bmi1 and Ezh2 alone, or in combination with established mammary tumor models that closely resemble human disease. Using these mice, we will investigate whether a) knockdown of Bmi1 and Ezh2 causes a regression of the normal and/or cancer stem cell compartment and b) whether this can be exploited to eradicate mammary tumors. Understanding the way in which Ezh2 and Bmi1 exert their effects may lead to novel targeted therapies for breast cancers, which may lead to the eradication of those cells that have the capacity to initiate tumor recurrence. We are confident that the proposed studies, many of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Sustainable production of next generation biofuels from waste streams' under Horizon 2020.

assistant: **Concept**

WASTE2FUELS aims to develop next generation biofuel technologies capable of converting agrofood waste (AFW) streams into high quality biobutanol.Butanol is one of the most promising biofuels due to its superior fuel properties compared to current main biofuels, bioethanol and biodiesel. In addition to its ability to reduce carbon emissions, its higher energy content (almost 30% more than ethanol), its ability to blend with both gasoline and diesel, its lower risk of separation and corrosion, its resistance to water absorption, allowing it to be transported in pipes and carriers used by gasoline, it offers a very exciting advantage for adoption as engines require almost no modifications to use it.  The main WASTE2FUELS innovations include:•    Development of novel pretreatment methods for converting AFW to an appropriate feedstock for biobutanol production thus dramatically enlarging current available biomass for biofuels production•    Genetically modified microorganisms for enhancing conversion efficiencies of the biobutanol fermentation process•    Coupled recovery and biofilm reactor systems for enhancing conversion efficiencies of Acetone-Butanol-Ethanol fermentation•    Development of new routes for biobutanol production via ethanol catalytic conversion•    Biobutanol engine tests and ecotoxicological assessment of the produced biobutanol•    Valorisation of the process by-products •    Development of an integrated model to optimise the waste-to-biofuel conversion and facilitate the industrial scale-up•    Process fingerprint analysis by environmental and techno-economic assessment•    Biomass supply chain study and design of a waste management strategy for rural developmentBy valorising 50% of the unavoidable and undervalorised AFW as feedstock for biobutanol prod
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Inter-Allied Cultures and Identities during World War 1' (2007-2013) under Seventh Framework.

assistant: **Objectives**

This innovative project aims to explore a neglected aspect of the experience of the First World War: the intercultural contacts and exchanges between and within the forces which made up the Entente. The project will investigate the construction of an Allied identity that was meant to ensure the cohesion of a multinational Allied coalition.Coalition warfare has arguably become the dominant type of military operations for European nations. A question of contemporary import for policymakers, the challenges raised by multinational military operations first came to light during the First World War, a conflict which pitted two formidable coalitions. Moreover, the Entente powers fielded soldiers recruited across their respective empires. The recognition of the multicultural nature of the First World War is at the core of the current debates over the experience of war in the twentieth century. The memory of the First World War thus feeds into current polemics over multiculturalism.This project will look into the articulation of Allied and national identities, as historians keep on debating the role played by the latter in bolstering the endurance of combatants. The project will contrast the emergence of this Allied identity with the efforts made to maintain communal identities during and after the conflict. The attitude of the Allied leadership towards 'coloured' troops and their segregative policies will be scrutinized as part of their effort to create and maintain a sense of community among allied troops. Interracial contacts raised a series of cultural, legal, and military issues during the conflict. Relationships between colonial troops and European soldiers and civilians, between white and black combatants in the American case; all shed light on the cultural management of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'MODELLING SOFTWARE PLATFORM FOR CERAMIC BODY OPTIMIZATION' in the context of a Horizon 2020 call.

assistant: **Objectives**

In the ceramic industry, optimization of ceramic body compositions, that is, the selection of raw materials and additives to provide some desired properties, is key to develop successful new products, ensure profitability and reduce environmental impact.  However, the traditional process to carry out this optimization, through trial and error, is widely inefficient. The learning process can take two years or more to define optimal body compositions and very often the optimum is never reached. In a context of increasing global competition, long trial and error optimization processes of ceramic body composition is today a great barrier preventing ceramic companies to remain competitive and innovative. NEOSAWARE is the first software solution applying Artificial Intelligence, computer simulation and mathematical optimization to accelerate by an order of magnitude the learning process which leads to optimal ceramic body compositions. By doing this, NEOSAWARE is capable of performing highly accurate predictions on the behaviour of body compositions on ceramic manufacturing processes and final products. It also enables to identify optimal ceramic body compositions to minimize production costs, ensure quality standards and minimize environmental impacts. NEOSAWARE is aimed to boost profitability of a wide range of players along the value chain of the ceramic industry.We expect to accelerate our implementation and international growth led by the commercialization of NEOSAWARE. We envision to reach a sales forecast of €19 million after 5 years of sales, with a ROI of € 4.8.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Investor Cliques in Stock Markets' (InvestorCliques).

assistant: **Concept**

Complex networks theory during the last two decades has gained novel results and profound insights into many complex systems in engineering, social and biological and also financial fields. This proposed data-driven research programme will apply cross-disciplinary complex network approaches to identify investor cliques in stock markets and to explain the impact of investor behaviour on asset price dynamics. My research extends current knowledge on investor networks by focusing on the identification of investor cliques to understand how different groups of investors (i.e. cliques) drive the market in certain direction. This research helps to understand the mechanism between investor behaviour and transitions in stock markets, an important information to identify early warning signal and detect market manipulation. Also, it justifies regulators to get a better access for investor level transaction data, such unique data set we use in this project, to plan effective policies. Moreover, information diffusion in financial markets is a fundamental question, which will be addressed by this research, especially focusing on information transfer between and within investor cliques. Methodologically, the project utilizes and develops clique enumeration techniques to identify network clusters. By analyzing the structure evolution of the investor multiplex networks and cliques, I am to detect if and how the structural changes are coupled between the different layers of the network and how the changes spread over all of the market. By using Vector Autoregression, inter-dependencies among multiple time series on investor networks and stock price processes can be identified with time-lagged influences. This computationally intensive research is implemented on a parallel computation pla
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Occupational cancer epidemiology in Europe' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

To establish a network of European occupational cancer epidemiologists and to conduct three subprojects: (i) an epidemiological study on cancer risk among European pulp and paper workers; (ii) an epidemiological study on cancer risk among European asphalt workers; and (iii) an epidemiological study and a conference on occupational cancer among European women.Although the pulp and paper industry is very important in Europe, relatively little is known of the possible cancer risk linked to employment in it. Exposure to different potentially carcinogenic agents occurs in this industry, and there is a need for studies involving large groups of workers to be able to address the problem of the exposure to specific chemicals, such as organic chlorinated compounds. An international cohort study has been started in several European countries, and will be completed under the present proposal. Employment in the asphalt mixing and paving industries entails exposure to polycyclic aromatic hydrocarbons, a class of carcinogens; the level of exposure depending on the type of asphalt used. Although an increased risk of lung cancer has been shown in association with exposure to fumes from coal-containing asphalt, little data are available on the risk of workers exposed to coal-free asphalt, the main type of product used in many European countries. The epidemiological investigation of these workers is hampered by the low quality of information available on exposure and by the high mobility of the workforce. A feasibility study has been conducted in Europe, which has shown that a cohort study is feasible in at least seven countries. The cohort will be assembled and followed-up under the present proposal. Women have traditionally been a neglected group in occupational cancer research: only r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Reduction of negative impact of environmental factors on human health' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

The Centre is gathering multidisciplinary research groups working on projects aimed to reduce negative impact of stress and inadequate nutrition. As these aspects concern health problems in all European countries, the Centre collaborates with outstanding scientists and participate actively in research work within the network of European Union laboratories. The activities of the Centre include training of young scientists and regular organisation of international symposia.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Continuous self-assembly using enzyme mediated supramolecular switching' to be submitted under Horizon 2020.

assistant: **Abstract**

Supramolecular chemistry has resulted in truly sophisticated architectures, many of which are able to exert specific functions, as well as to change and adapt in response to external stimuli. So far, however, artificial structures with a similar functional complexity as living self-assembled systems are lacking. This is because nearly all current supramolecular systems are in thermodynamic equilibrium or kinetically trapped states. Living systems, on the other hand, operate far from equilibrium in so-called dissipative steady states, and continuously consume energy to keep their structure and function. Mimicking nature, here we propose to prepare dissipative self-assembled steady states of synthetic discotic molecules, controlled by competitive enzymatic pathways (phosphorylation / dephosphorylation), in which the supramolecular assemblies are kept far from equilibrium by a continuous perturbation i.e. the influx of a chemical fuel. We expect to get fundamentally new insights into non-equilibrium self-assembly, opening the door to truly adaptive, self-healing, life-like complex artificial systems. The candidate will be trained in a promising new research area in one of the hotspots for supramolecular chemistry in Europe, which would be a great stepping stone for his future independent research career.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'FUNCTIONAL GENOMICS OF THE ADULT AND DEVELOPING BRAIN' (NFG) targeting Sixth Framework.

assistant: **Abstract**

This proposal brings together researchers who are interested in neuronal dynamics and those interested in understanding how neural activity depends on gene expression. The unifying theme of the proposal will be to identify and characterise complex, physiological electrical activity of cells and networks, and to understand how such global dynamics are orchestrated at a cellular and molecular level in patterns of gene expression. The project will focus on two tissue types of primary importance in the nervous system: sensory receptors (olfactory and visual) and cortex (hippocampus and neocortex). A central strategy will be to identify and classify specific types of projection neurons, interneurons and sensory neurons, in term of both their electrophysiological behaviour and the profiles of expression of thousands of genes and transcripts. After electrophysiological characterisation of neurons by whole-cell patch-clamp, single cell RT-PCR of the cytoplasm of single cells will be used in conjunction with DNA array analysis.Using this expression profile data, new cell-specific markers will be identified and used to make transgenic animals with markers such as GFP and PLAP. Cell-sorting techniques will be applied to harvest large numbers of labelled neurons for the most complete expression analysis. The project will apply theoretical concepts and methodologies for statistical and dynamical analysis, to interpret and model the experimental data. In summary, we expect to obtain significant new understanding of: the composition of large neuronal assemblies in terms of cell types; differences and similarities in gene expression among neuronal populations in the adult nervous system; how the global properties of large neuronal assemblies are regulated by the presence of specific ne