RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Artificial intelligence Supporting CAncer Patients across Europe' (ASCAPE) under Horizon 2020.

assistant: **Objectives**

The latest cancer statistics highlight encouraging advances in decreasing cancer-related mortality. However, given that one in two people will be diagnosed with cancer in their lifetime, and due to the growing and ageing population, the absolute number of people living with cancer is set to keep increasing substantially in the near future. The main objective of ASCAPE is to take advantage of the recent ICT advances in Big Data, Artificial Intelligence and Machine Learning to support cancer patients’ quality of life and health status. To achieve its objective, ASCAPE will create an open AI infrastructure that will enable health stakeholders (hospitals, research institutions, companies, etc.) to deploy and execute its AI algorithms locally on their private data. Any new knowledge produced by this process will be sent back to the open AI infrastructure. This way the knowledge will be shared among everyone while the medical data will still remain private. The services to be designed, piloted and deployed inside this project will include intelligent interventions for physiological and psychological support, improved patient and family counselling and guidance, early diagnosis and forecasts of ill-health, identification of disease trajectories and relapse, improved health literacy etc. ASCAPE will focus the training of the AI in two types of cancer, breast and prostate. This way, it will achieve sufficient coverage across genders as well as age groups, hence facilitating its ongoing improvements and applicability towards any type of cancer in the future. The ASCAPE project will be developed in 36 months by a competitive consortium of 15 partners from 7 countries, which corresponds to a well-balanced structure, involving big companies, SMEs, research centres and universities.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'High field magnet laboratory / resaerch institute for materials' (MAGNETS) under Fifth Framework.

assistant: **Objectives**

The High Field Magnet Laboratory makes available high continuous magnetic fields using resistive, super-conducting and hybrid magnets with field-strength up to 30 tesla. The University of Nijmegen is now building a new and more powerful installation, which from the beginning of 2003 will provide magnetic fields up to 3 3 tesla at a turn of the knob with resistive magnets. This installation will be equivalent to the best available anywhere in the world. Access to the high field resistive, super-conducting and hybrid magnets is provided for qualified and selected user projects concerning fundamental physics, chemistry and materials research, up to 400 magnet-hours per year: roughly 30% of t he infrastructure's yearly capacity (in total 900 hours for the contract). The access includes the use of supporting equipment, and the available cryogenic and spectroscopic instruments, and high-level scientific and technical assistance; travel and subsistence can be offered for the selected and eligible guest researcher.Access to the facility can be obtained by submitting a research proposal; forms can be obtained upon request (hfmlsecr@sci.kun.nl) or can be downloaded from the homepage. Proposals are evaluated by a selection committee chaired by prof.dr.ir. J.C. Maan and are judged on the basis of scientific quality, technical feasibility and t he necessity for use of the infrastructure. Project Manager: J.C. Maan Laboratorium voor Hoge Magneetvelden, Faculteit Natuurwetensschappen, Wiskunde en Informatica Toernooiveld 1 Nijmegen 6525 ED The Netherlands Tel: +31-24-3653422 Fax: +31-24-3652314 E-Mail: marthag@sci.kun.nl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Linking extensive husbandry practices to the intrinsic quality of pork and broiler meat' (2014-2020).

assistant: **Concept**

The mEATquality project aims to provide consumers with quality pork and broiler meat, by developing novel solutions that address societal demands, environmental concerns and economic needs on farm and in the chain. The ‘extensiveness’ of production is a key issue, and will be developed in a stepwise approach. The first step surveys extensive husbandry factors in relation to intrinsic meat quality, through data collection on conventional, free-range and organic farms, and through consumer expectation studies. The second will include controlled experiments on-farm to investigate intrinsic meat quality characteristics in relation to husbandry factors: genetics, forage, space and enrichment. It will also develop innovative techniques for automated meat quality assessment at high line speeds, and combat food fraud through authentication of the final product via ‘fingerprinting techniques’ and blockchain technology. The third step will check the novel farming practices against sustainability aspects: animal welfare, environmental impact and economic viability. Market acceptance of the new products and ways to communicate them to consumers will be studied. The fourth and final step will communicate and disseminate the results. Key outputs are an ‘Extensive Practices’ app, animated movies and EIP Practice Abstracts for farmers, educational tutorials for consumers, retailers and restaurants, and an EU Meat Database for authentication purposes. mEATquality is proposed and co-designed by organic sector representatives Ecovalia and Naturland, in collaboration with CLITRAVI, the Liaison Centre for the Meat Processing Industry in the European Union. They joined forces with academic partners (including 5 of Europe’s leading meat quality laboratories), Marel (poultry, fish, meat & furt
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'International Conference on Research Infrastructures  (ICRI) 2018 in Vienna' (ICRI) targeting Horizon 2020.

assistant: **Abstract**

ICRI 2018Research infrastructures are among the core enablers of competitive research alongside basic science, development and innovation to advance the frontiers of our knowledge. These research infrastructures are often operated by international consortia and are applicable in various disciplines and stakeholder communities. Research infrastructures are constantly under pressure to adapt due to the advancements in science, research and technology. All these aspects underline the importance of research infrastructures but at the same time demonstrate the challenges and the complexity that occur within the construction, implementation, operation, funding and international cooperation. This calls for an exchange and discussion on an international level regarding topics such as governance, operations and the general policy area for research infrastructures. Respecting the need for international attention to the aforementioned policy area, the ECRI was vital towards establishing a conference format that can lead a new millennium onwards. Subsequently, the focus was widened to an international level (ICRI).The overall objective of this proposal is to organize and further establish this dynamic international forum on research infrastructures (ICRI), under the 2018 Austrian EU Council Presidency. The ICRI will gather relevant experts, shareholders and stakeholder communities of research infrastructures to discuss challenges and emerging trends for research infrastructures around the world.The specific objectives of the proposed action are as follows:- Addressing issues of global interest Development of global research infrastructuresLong-term sustainability Innovation potential of research infrastructuresAccess and exploitation of data produced by research infrastructures- En
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Copy number variations conferring risk of psychiatric disorders in children'.

assistant: **Concept**

The recent technical improvements for the study of the cytogenetic basis of disease have led to the identification of many microdeletion and microduplication syndromes. De novo copy number variants (CNVs) are seen more often than expected in autistic patients, and rare chromosomal aberrations are known to account for a small fraction of schizophrenia and bipolar disorder. Recurrent spontaneous mutations at multiple sites across the genome may be a prime cause of these disorders, and the reduced fertility associated particularly with autism and schizophrenia may, through selection pressure, maintain these variants at very low frequency. CNVs are large enough to be identified using cost efficient genome-wide search techniques, such as oligonucleotide arrays. In contrast, rare DNA mutations might confer a large proportion of the overall genetic risk, but cannot be easily identified at the present time. Genetic epidemiology suggests that autism, bipolar disorder, and schizophrenia are highly heritable and share susceptibility genes. However, the results of dense SNP array-based genome wide association scans for these disorders have been disappointing, as no high frequency risk alleles have been identified. The PsychCNVs consortium will apply oligonucleotide arrays for the large-scale interrogation of CNV variation in the human genome, focusing on people with autism and childhood onset schizophrenia and bipolar disorder, where CNVs are likely to be more common. This project follows on logically from our hypothesis-independent genome-wide SNP search for common variants, we now intend to systematically search for large, rare CNVs conferring high risk. The genetic risk conferred by CNVs will be estimated by genotyping samples from 2800 patients, to identify de novo or recent sp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Probing electrically charged Higgs bosons at the CERN's Large Hadron Collider: a collaboration between theory and experiment' under Seventh Framework.

assistant: **Concept**

This collaborative project is in the area of high-energy particle physics phenomenology with the focus on electrically charged Higgs bosons. The proposal is a research programme where the applicant's expertise on various aspects of charged Higgs boson phenomenology in hadronic collisions is well-matched with that available at the host institution. The NExT institute has several leading world experts on the phenomenology of the Standard Model (SM) at present and future high-energy colliders both at the theoretical and experimental level (with groups working on the CMS and ATLAS collaborations at the CERN's LHC facility, where the aforementioned studies will take place). Moreover, NExT's mission is to promote fundamental research where theorists and experimentalists work together in the process of New Physics discovery, and the applicant is the ideal catalyst for this since his theoretical work has influenced experimental collaborations in the past. Hence this project will produce forefront research, mutually advantageous to both parties, based on a new raw model of a researcher with interdisciplinary skills. We are especially interested in the search for electrically charged Higgs bosons. Such particles are a necessity in numerous extensions of the SM which address its empirical and theoretical shortcomings. It is widely believed by contemporary particle physicists that the elusive Higgs bosons (both electrically neutral and charged) are potentially the key to answer the fundamental question of why elementary particles have mass. Their search is therefore the primary goal of the LHC. Overall, our aim is to contribute to a better understanding of the world of particle physics by performing, developing, and optimising both Monte Carlo and real data analyses to confirm or c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Deconvoluting Signaling Activities of Mitochondrial-derived Reactive Metabolites with Unparalleled Depth and Spatiotemporal Precision' (2021-2027).

assistant: **Concept**

Mitochondria-derived reactive metabolites (mt-REMs) drive context-specific immunomodulatory behaviors during metabolic reprogramming. Yet, no method can interrogate the cause-and-effects of individual mt-REMs with locale specificity and temporal resolution. Mapping mt-REM-directed signaling changes with spatiotemporal resolution would thus be transformational.  I will develop a spatiotemporally-resolved in-vivo mt-REM-responsivity-mapping technology. This cross-disciplinary innovation will enable localized build-up of an individual mt-REM in one specific cell type with precise temporal, dosage, and chemotype control. For the first time, I will map cell-type-specific “first responders”, proteins attuned to react with the specific mt-REM in an otherwise unperturbed system, in a manner that alters signaling across distinct disease contexts. My ability to assimilate chemical biology, organic/medicinal chemistry, & biotechnology enables me to achieve these goals leveraging functional mechanistic models principally zebrafish, mice, and cultured primary cells. The resulting new knowledge is biomedically important: my previous work on lipid-derived metabolites supports that we can leverage this information to design drug candidates. This research project promises transformative biomedical advances and technological breakthroughs with enormous potential for unveiling reactive metabolite-guided biological mechanisms influencing cell function & disease outcomes.


**Keywords:** Chemical Biology, Biotechnology, Bioengineering, Reactive metabolite signaling subsystem
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Developing Genetic Tools to Mitigate the Environmental Impact of Dairy Systems'.

assistant: **Innovation**

The EU25 produce approximately 132 million tonnes of milk from 24.3 million cows on 1.76 million farm holdings. Ruminant animals account for up to 20% of the world methane production with the EU25 dairy population producing approximately 3.2 million tonnes of methane (CH4) per year. Many EU countries have specific and binding commitments relating to the reduction of GHG emissions, and all sectors of the economy are coming under increasing scrutiny in relation to their share in the overall emissions target. Little work has been done on the role of dairy cow genetics in dairy system emissions, particularly considering the role of genetics in the whole farming system, including feeding strategy and management policies (e.g., energy balance, housing periods, fertilisation and manure management). GREENHOUSEMILK will help us understand the role of energy efficiency and partitioning in the overall GHG output of dairy systems and develop innovative tools to help farmers’ select “environmentally friendly” bulls to suit their system and how to manage those bulls’ daughters in an appropriate manner. GREENHOUSEMILK will harness statistical and genetic tools to elucidate the genetics of emissions in dairy cattle and develop innovative and integrative tools that address the environmental impact of dairy farming, thus underpinning a high priority policy area. GREENHOUSEMILK will build on data, resources and expertise being developed in the FP7 KBBE-2007-1 funded project RobustMilk. Utilising the resources and skills from RobustMilk to address other questions is highly beneficial and synergistic and will add to the outcomes of both projects. GREENHOUSEMILK will examine: 1. causes of variation in CHG emissions in dairy cows, 2. genomic tools to help select for reduced CHG emissions, 3.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'RETROFIT AND ARCHITECTURAL INTEGRATION OF PV MODULES IN FACADE 1 ROOF OF AN OFFICE AND LABORATORY BUILDING, PETTEN' under Fourth Framework.

assistant: **Concept**

To encourage the application of PV-systems as part of the retrofit of a laboratory and office building. This renewal will increase the energy efficiency of the building. Energy consumption will decrease with 75% thermal energy and 35% electrical energy.The south facade with large windows will be renewed with a sophistical shading system with integrated PV-system. The quality of daylight will be better in combination with this system. The heat load of the building will be decreased. Energy savings by the PV-structure are 91% of the electrical energy for the building (artificial light, transportation, installations); The PV system is grid connected. These aspects will be architecturally integrated into a new facade.Detailed design of lamellas, PV system, support system, mock-up; daylighting simulations, first model of lamella prototype section scale 1:1.ENERGY TECHNOLOGY OBJECTIVES OF THE PROJECT:The building is a typical example of a building with poor thermal insulation, heat bridges and bad energy consumption. Goal of this project is to achieve a successful integration of PV for both roof and facade applications, that will improve the energy efficiency of the building.In particular the project propose to improve the quality of daylight and decrease the heat load of the building by :- the introduction of a new sophisticated technology of shading device with integrated PV systems on the south facade; - an innovative construction system for the integration of PV on the roof. The demonstration aspects are :* the 70 kWp PV-system in 3 different integrated structures wall 10 kWp roof 25.8 kWp facade 33.6 kWp* architectural integration of PV-system in an existing building (retrofit)* optimizing the solar gain and electricity output by the use of a PV-integrated shading system
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Product Remanufacturing Service System', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

For centuries mankind has attempted to exploit the resources available to it through the reuse of objects and artifacts.  However, as wealth of modern man has grown, the financial necessity to utilize the lifetime of these objects has dramatically declined, especially in developed countries with high focus on manufacturing.  The demand for new products also placed undue pressure on the world's resources, creating an ethical imperative to conserve and reuse. Remanufacturing is the process of bringing used products to like-new" functional state with an equivalent quality assurance. As this activity provides profitability whilst reducing land-filling and usage of virgin material, it is a financially viable as well as a sustainable business concept.<br/>One of the key issues deterring the uptake of remanufacturing is the information gap which is created when products leave the OEM. The information gap is the result of the lack of data on product usage and its lifecycle. In general, the product user possesses much greater knowledge regarding a product as he has used it, repaired it, and replaced components. This, in turn, results in the fact that the input to the remanufacturing process is of unknown quality. The lack of reliable information on product usage and lifecycle leads to missed opportunities with respect to increased economic or environmental impact.<br/>The goal of PREMANUS is to overcome the asymmetric distribution of information in the End-of-Life (EoL) recovery of products, with a special emphasis on remanufacturing. To achieve this goal, PREMANUS will provide an on demand middleware which combines product information and product services within one service oriented architecture. In addition to closing the information gap, the PREMANUS middleware would compute