RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Network for Observation of Volcanic and Atmospheric Change' under Sixth Framework.

assistant: **Concept**

The idea of the NOVAC project is to establish a global network for measurement of volcanic gas emissions, based on the Scanning Dual-Beam mini-DOAS instrument developed in the EU project DORSIVA. Primarily the instruments will be used to provide new parame ters in the toolbox of the observatories, for risk assessment, gas emission estimates and geophysical research on the local scale. In addition to this, data are exploited by the project partners for other scientific purposes then local volcanic gas emissio ns; large scale volcanic correlations, satellite validation, studies of climate change and studies of stratospheric ozone depletion.The Scanning Dual-Beam mini-DOAS instrument represents a major breakthrough in volcanic gas monitoring. The instrument is ca pable of real-time automatic unattended measurement of the total emissions of SO2 and BrO from a volcano with better then 5 minutes time resolution, over the daylight day. Besides providing an accurate determination of the total emissions of SO2 and BrO fr om the volcano, the high time-resolution of the data enables correlations with other geophysical data, e.g. seismic data. Thus significantly extending the information available for real-time risk assessment and research at the volcano. By comparing gas emi ssion data, with emissions from neighbouring volcanoes on different geographical scales, or with other geophysical phenomena (earthquakes, tidal waves...) mechanisms of volcanic forcing may be revealed.The spectra recorded by the instrument will also be us ed to derive data from complement global observation systems related to climate change and stratospheric ozone research. Taking advantage of the fact that many volcanoes are located in remote areas sparsely covered by existing networks.The consortium compr i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Twinning for Excellence in Management and Economics of Research and Innovation' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The adoption of the new Pact and Governance for the European Research Area (ERA) that includes a new regime for open science endorsed by all EU27 competent ministers for R&I, the need for research integrity and a common set of principles and values to reaffirm solid foundations of R&I (ethics, freedom of scientific research, gender equality and equal opportunities), the increased free circulation of researchers, innovators and knowledge, the cultural distance of R&I consortia and the engagement of citizens in science and innovation and regional convergence in R&I capacity are areas that need rigorous attention. Also, the determinants of R&I productivity, the role and efficiency of R&I funding and both experimental approaches and theoretical economic models that can enable better understanding of the interactions of different actors in a R&I ecosystem are of utmost importance. The Twinning for Excellence in Management and Economics of Research and Innovation (TWIN4MERIT) project aims to examine these meta-research areas of critical importance by facilitating a partnership with two advanced partners in the field in order to advance all related research activities at the University of Cyprus (UCY). This vision will be realised by applying for a Horizon Europe/Twinning grant, in conjunction and under the aegis of the Research and Innovation Service of UCY and the “SInnoPSis” research unit for Science and Innovation Policy and Studies, which is part of a secured H2020/ERA Chairs project by UCY. This newly established research unit coupled with the new network of advanced partners of the TWIN4MERIT proposal, UM and UC3M, will facilitate the gradual upgrade of the research activities in the field both in Cyprus and internationally. The research excellence of the advanced partn
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Improving flower attractiveness for pollinators:  Study of developmental, morphological and chemical cues  in relation to bee foraging' under Horizon Europe.

assistant: **Concept**

Animal pollinators are vital for life on earth. While human population keeps growing, pollinator populations are dropping, thus threatening food security. In agriculture, the main insect pollinators are bees, by far.The lack of knowledge on how domesticated plants attract and reward bees has hampered the selection of varieties with improved and mutually beneficial crop-pollinator relationships. We propose to investigate flower features, including developmental, morphological and chemical cues, in relation with bee foraging. Elucidating the molecular basis of these processes would not only help sustain yields, but it is key to understand the co-evolution of plants and pollinators.We chose melon as a model system, because it is a strictly entomophilous crop, and because it provides all flower sexual morphs useful to probe plant-insect interactions. ForBees is a multidisciplinary project that integrates molecular genetic analysis and precise phenotyping. First, we will study melon genetic biodiversity with the aim to identify alleles that control nectar-related traits and bee attraction. The comparative analysis of wild accessions, landraces and breeding lines will further test whether domestication led to the loss of useful traits affecting insect visits. Second, we will analyse the gene networks that drive nectar gland development and nectar production. Finally, potential key regulators will be validated genetically. Through this work, we aim to develop a toolbox to tailor the morphology and chemistry of the flowers towards improved bee foraging activities.In addition to research in melon, results from this project, and from previous works, will be translated into neglected crops of the Cucurbitaceae family. These are major food crops in many developing countries, ensuri
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Study of the CD200/CD200R pathway in the pig-to-human setting to elucidate the molecular bases of xenograft rejection and develop approaches that promote xenograft survival.' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Xenotransplantation aims to provide a therapeutic solution to many patients that suffer tissue or organ dysfunction. However, porcine xenografts transplanted into primates are rejected by humoral and cellular responses resistant to immunosuppression. Ident ifying the molecular bases of xenograft rejection and developing strategies to overcome them is crucial to achieve long-term graft survival. Accordingly, this proposal aims to study the role of innate immunity in this rejection process and particularly, th e interaction of porcine CD200 (pCD200) and the human CD200 receptor (hCD200R). It also seeks to develop strategies that promote CD200R signalling to prolong xenograft engraftment. It is known that engagement of hCD200R triggers inhibitory effects in cells of myeloid lineage. In this work, the main objective is to clone and sequence the pCD200 cDNA, characterize the protein and assess its binding to hCD200R. It also aims to study the expression pattern of pCD200 to compare it to the mouse and human counterp arts. The porcine and human CD200 will be expressed on porcine cells by genetic engineering to assess its effects on human immune responses in vitro using mixed cultures. The function of CD200 can be further evaluated in combination with other approaches s uch as CD86 blockade. Animal models will follow to explore its potential protective effect in vivo. To this end, I will develop pig-to-mouse cellular transplant models to evaluate the efficacy of systemic CD200Ig treatments and/or CD200 overexpression on t he porcine donor cell. The in vivo studies will focus on studying the cellular immune rejection by histologic examination and the humoral response by determining the elicited antibody titers. If these strategies prolong xenograft survival, this study will rep
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Artificial Intelligence and Machine Learning for Enhanced Representation of Processes and Extremes in Earth System Models' (AI4PEX).

assistant: **Innovation**

Global warming continues at an alarming rate, presenting unprecedented challenges to society that require urgent, science-led mitigation and adaptation. Earth system models (ESMs) are essential tools for projecting climate change, providing important information to decision makers. However, confidence in predicted climate change is undermined by a number of uncertainties; (i) ESMs disagree on how much the Earth will warm for a given increase in atmospheric carbon dioxide (CO2) (Earth’s equilibrium climate sensitivity); (ii) how much emitted CO2 will stay in the atmosphere to warm the planet (half the CO2 emitted by humans has been absorbed by the land and ocean) and (iii) how much excess heat in the Earth system will enter the ocean interior, delaying surface warming (~90 % of the heat in the Earth system goes into the ocean). Central to these uncertainties are poorly understood, and poorly modelled, Earth system feedbacks, in particular cloud feedbacks, carbon cycle feedbacks and ocean heat uptake. Poor representation of these phenomena degrades the accuracy of ESM projections, with implications for anticipating future climate extremes and societal impacts. We aim to improve the representation of these feedbacks in ESMs, reducing uncertainty in global warming projections. We propose a multidisciplinary approach, focused on “learning” how to accurately describe processes underpinning these feedbacks, through a fusion of observations with advanced machine learning (ML) and artificial intelligence (AI). Such data and approaches, constrained by the laws of physics, will deliver a step change in the accuracy of Earth system models. AI4PEX will place Europe at the forefront of a revolution in Earth system modelling, leading to increased accuracy of climate change projections
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'An EnhaNceD Common InfoRmatiOn Sharing EnvironMent for BordEr CommanD, Control and CoordinAtion Systems' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The project aims to unlock the full potential of CISE, by validating in a long period of time CISE-compatible command, control and coordination systems from several Coast and Border Agencies. At the same time it is envisaged to further enhance, validate and demonstrate CISE by extending its scope for land borders and adapting relevant C2 solutions and associated services. This will be accomplished by extending the CISE data model based on the use cases and requirements and adapting state-of-the-art command & control systems for full compliancy with the enhanced model and CISE message exchange patterns. The project architecture will follow a hybrid scheme in order to allow the usage of the End User CISE Nodes/Gateways and at the same time to allow the testing and validation of the extended data model. The project will leverage on the developments, results and experience of the consortium from current and previous research projects (PERSEUS, CloseEye, MARISA, RANGER), from National Procurement projects of CISE Nodes and Adaptors and on the CISE infrastructure of the End Users.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Early modern Catholic representations of Hinduism' (HINDREP), addressing dissemination and exploitation.

assistant: **Impact**

This two-year project is a contribution to the current post-colonial debates on orientalism and, more specifically, on the extent to which Hinduism was also a European construction. The aim is to  analyze the representations that Catholic missionaries developed between the Seventeenth and the early Eighteenth centuries to interpret Hinduism. The period considered follows the end of the Portuguese monopoly on the sea route to India and precedes the emergence of secular indology. From the early seventeenth century, Jesuit missionaries as Giacomo Fenicio, Roberto Nobili and Gonçalo Fernandes composed detailed descriptions of Indian “heathenism” that were circulated in manuscript form and plagiarized extensively. Elementary notions of Hinduism were found in printed versions of Jesuit letters and in works published by members of other religious orders. Using archival material, printed works and visual sources, I will analyse how theology, antiquarianism and classical learning were deployed in order to understand a religion that the missionaries wanted to replace with Catholicism. By basing myself at the Warburg Institute, London, I will be trained in the study of the classical tradition and early modern scholarship; moreover, I will benefit substantially from the Institute’s world-renowned tradition of using visual sources as evidence of anthropological representations. My project will test the hypothesis of a specifically Catholic early modern representation of Hinduism by examining the tensions between a common Catholic framework and differences in national backgrounds and religious orders, as well as investigating the circulation of indological knowledge in Europe between Catholics and Protestants. The goal is a book that will contribute to a comprehensive history of the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Implementation of integrated and innovative Precision Agriculture management strategies to reduce the occurrence of ochratoxins along the vine value chain products: grapes, raisins/currants and wine' (2014-2020) under Horizon 2020.

assistant: **Objectives**

The risk of mycotoxins is a global issue that represents a serious risk for human and animal health. Οchratoxin A (OTA) is a very toxic mycotoxin that constitutes a severe problem for viticulture and taking into account the extreme climatic events that are frequently faced in recent years, the OTA problem is arising in wine and raisins/currants. OchraVine Control project will offer an inexistent innovative, sustainable and integrated smart ICT solution (OchraVine Control DSS) considering fungal, host and environmental indicators that affect OTA contamination along the vine grape-wine value chain. The OchraVine Control DSS will allow prediction and monitoring at pre- and post-harvest level to control Aspergillus infection and OTA contamination in vine cultivation by combining epidemiological data, biological and chemical management strategies, post-havrest technologies and precision agriculture tools. OchraVine Control DSS solution will pursue a field-to-fork approach and will link and translate the information derived from the OchraRisk and OchraDetect predictive map tools and real data obtained during the monitoring controls by the OchraSensor. OchraVine Control DSS tool will be placed in an open access web platform and in combination with data from the OchraRed Integrated Management Strategy will provide risk prediction information (i.e. geographic OTA vine alerts), practical recommended solutions for OTA management and will verify the compliance with legislation requirements in a rapid and cost-effective way. The project will have a multi-actor international approach involving 3 RTDs and 5 SMEs that will exchange skills and knowledge and will all have a vital role in the design of the solutions, implementation, testing, dissemination, communication and economic explo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'TRANSCRIPTOMICS IN CANCER EPIDEMIOLOGY' under Seventh Framework.

assistant: **Concept**

NOWAC is the first prospective study with a globolomic design. This is an extension of the current cohort study with its questionnaire information and biological material for analysis of biomarkers, proteomics and single nucleotide polymorphisms (SNPs). The design of NOWAC adds biological material for analysis of the transcriptome in prospectively collected buffered peripheral blood samples, the postgenome biobank. Further, both peripheral blood and tumor tissue are collected from breast cancer patients diagnosed within the cohort together with matched controls. The latter biological material gives a new multidimensional design with a unique biological material at the end-point. The transcriptomic analysis will include both mRNA and miRNA as new technology (microarray and massive parallel sequencing) allows large scale studies. miRNAs could be promising markers for pathways analysis related to the carcinogenic process and for diagnosis and screening tests of breast cancer. These high-troughput technologies have analyses challenges both in bioinformatics and biostatistics therefore success depends on the development of new analytical strategies.This novel design is the observational counterpart to systems biology, or systems epidemiology. Systems epidemiology will seek to understand biological processes by integrating observational derived pathways information into the current prospective design. A true interdisciplinary approach has been implemented. The upside is the potential for an improved understanding of causality in epidemiology by opening up for quantification of traditional criteria of biological plausibility in a more complete biological model.  The postgenome biobank with 50 000 participants out of the 172 000 participants in NOWAC and its unique national des
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'SUB-WAVELENGTH HOLOGRAPHIC LITHOGRAPHY STEPPER FOR INTEGRATED CIRCUIT PRODUCTION' (HOLISTEP).

assistant: **Concept**

To achieve ever shrinking dimensions and higher resolutions of circuit elements, projection lithography (PL), is growing in complexity and cost to manufacturers. It is limited to producing 2D images on flat surfaces. Extension to 3D imaging is restricted by trade-off between focus depth and resolution. Advanced, cost-efficient solutions to fabricate wafer-scale 3D components are required.HoLiSTEP unleashes the potential of sub-wavelength Holographic Lithography (HL) as a powerful and enabling disruptive lithography. HL will overcome limitations of PL and facilitate production of novel 3D topographies with high resolution while making the production of high-resolution IC much more affordable.An industrial prototype operating at 345nm with 200nm resolution will be produced and validated in an operational environment. Several advancements in holographic stepper subcomponents must be realised: A UV fibre-based laser with 20W output power at 345nm and 1.5m coherence length, an alignment system with 25nm overlay precision, an adaptive optical system with correction precision of 1/20λ and software modules for vector diffraction models.Energy consumption of HL technology is drastically reduced compared to PL due to low power-consumption of the laser and production of complex structures in one exposure. HL images are not sensitive to mask defects, eliminating frequent mask replacements and use of toxic materials. Moreover, holographic masks act as projection optics, eliminating the need for complex optical systems.The HL prototype will be verified for 3D patterning for MEMS, MOEMS and micro-optical components to show better resolution, flexibility of 3D printing and reduced cost. HoLiSTEP will empower a positive transformative effect on environment, economy and society by enabli