RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'High precision material printer for electronics' (Preprint).

assistant: **Innovation**

The aim of the PREPRINT project is to obtain the much-needed improvement in terms of resolution of materials printers, in order to achieve the far-reaching goal of fabricating integrated circuits with Large Scale of Integration (LSI, i.e., thousands of transistors, the same level of integration of the first INTEL microprocessors) in printed electronic systems on wearable/flexible substrates. The number of transistors on a substrate is mainly determined by the resolution of the printing machines, which, today, is at most of the order of tens of micrometres.  The PI has successfully demonstrated within the PEP2D project (Contract No. 770047) that printed devices and simple circuits on flexible substrate as paper can be obtained with outstanding performance, while leveraging the exceptional electrical and mechanical properties of two-dimensional materials. Being able to pack thousands of these devices on the same substrate would path the way towards the realization of systems with improved performance and capabilities, while unleashing the full potential of printable and flexible electronics on a wide range of applications (from bio, to smart patches, anticounterfeiting, lab-on-a-chip, just to cite few).A step-forward in this direction has already been done by the PI through the demonstration of a material printer prototype with resolutions better (i.e., few micrometres) than those available in the market. Within the PREPRINT project, the technical and economic viability of obtaining printing resolution smaller than 1 micrometre will be explored: it is our belief that such a goal is at reach, while boosting the performance of the fabricated prototype, which will allow us to compete and early enter the fast-growing market of printable electronics and material printers.


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system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Microprobe multi-sensor for graft viability monitoring during organ preservation and transplantation' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

This proposal seeks to provide the medical community with an innovative way for reliable monitoring of organs during transplantation. The monitoring, done using a purposely developed microsystem, would provide means for continuous evaluation of organ feasibility both during transport and postoperative initial evolution. To-date, the need for a perfect temperature and pathogen isolation of the organ during transport has been a major barrier in evaluating the needs and results of a constant monitoring. The recent development of silicon micro-biosensors opens a way in which to attain this objective without resigning to the mentioned organ isolation. Any action taken to increase the number of organs viable and improve their postoperative function shall be welcome by the European Society. Objectives:The proposed project intends to assist (1) the viability assessment of organs due for transplantation, expanding thus the number of available grafts and their possible destinies, and (2) the monitoring of organ behaviour during the initial postoperative period. The technological goal of this project is to raise awareness in the microsystems field through their use in a biomedical application that also requires a high level expertise on microelectronics design. Development of applications displaying these sort of needs and requiring these kind of solutions will contribute to enhance the European industry competitiveness broadening the market for both the silicon industries and the biomedical industries themselvesWork description:The proposal will result in a new generation of medical devices for patient continuous monitoring. Through the use of available processes and microtechnologies quality of medical information and quality of assistance will be powered-up while reducing patie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'International Collaboration on Computational Modelling of Fluidised Bed Systems for Clean Energy Technologies' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

iComFluid will develop an EU-India network for fluidised bed technology research by uniting activities among 4 top ranking European and Indian universities. 28 researchers will be exchanged and trained with latest techniques covering the full range of thermal conversion for clean energy generation including pyrolysis, gasification and combustion. iComFluid will set the foundation stones for long-term strategic collaboration between EU and India to confront the challenge of climate change and clean energy generation in a global framework.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Novel Biomaterial for Improved and Cost-efficient Wound Healing' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Wound treatment is a major healthcare cost for all developed countries. The global market for advanced wound care products was projected to be $ 3 billion in 2012, with an annual growth above 10% and representing one of the leading medical product sectors. However, this represents only some 15-20% of the overall cost of wound treatment, where hospitalisation and nurse time represent the remaining costs.  BIOVOTEC aims to pursue a major market opportunity by developing a novel biomaterial based cost-effective wound dressings that can be used for initial treatment of all wounds at risk of delayed or non-healing, reducing the incidence of chronic wounds. BIOCURE range products will be safer, potentially more effective, much more easily scalable and significantly lower in cost when compared with the available advanced wound healing products.BIOCURE is an opportunity for BIOVOTEC to enter the world-wide advanced wound care market and maintain the European competitive position in the growing biotech and wound management sector. The accomplishment of the project objectives will thus represent a significant business opportunity for the two SMEs, with expected sales of over €50 million within 5 years of launch (i.e. 2022). Furthermore, BIOCURE will positively impact clinicians and patients through early stage treatment or resolution of chronic wounds and payers through reduced treatment costs per wound.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'SYNTHETIC GENE CIRCUITS FOR CLOSED-LOOP THERAPY' under Horizon Europe.

assistant: **Concept**

What if gene therapy could think, adapt, and act only when needed? SECURE sets out to create the world’s first self-adaptive gene therapy platform ‒ a transformative leap from today’s static interventions toward programmable, intelligent therapeutics. Rather than permanently active vectors, our approach uses synthetic gene circuits that remain dormant under healthy conditions and activate only in cells exhibiting disease-induced molecular stress. This ""on-demand"" precision therapy promises unprecedented safety, efficacy, and personalisation.As a first-in-class application, SECURE targets Parkinson’s Disease (PD) by focusing on vulnerable dopaminergic neurons identified through stress markers such as AGTR1 expression, inflammation, and oxidative damage. Using AI-guided design, we will engineer AAV and bocavirus vectors tailored for efficient blood-brain barrier (BBB) transcytosis and neuron-specific targeting, guided by human receptor maps from neurotropic viruses.Validation will rely exclusively on human iPSC-derived midbrain organoids ‒ including mosaic models combining healthy and PD genotypes ‒ to test selectivity, reversibility, and safety. A closed-loop development pipeline will be established, where data from single-cell transcriptomics, electrophysiology, and functional assays continually refine vector design through AI feedback.By integrating synthetic biology, AI, and advanced disease modelling, SECURE pioneers a new therapeutic paradigm for neurodegeneration and potentially for multifactorial and hereditary diseases at large. If successful, it will mark the beginning of preventative, adaptive, and lifelong gene therapy for complex human disorders.""


**Keywords:** mRNA switch; human midbrain organoids; single cell RNA sequencing; viral vectors; gene express
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'FLUid Image analysis and Description', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

This interdisciplinary project, that we have entitled FLUID, aims at studying and developing new methods for the estimation, the analysis and the description of complex fluid flows from image sequences. We propose to devise novel image processing and computer vision methods by using sound methodological frameworks incorporating suitable physical models accounting for the observed phenomena. This domain of research encompasses a wide range of difficult issues and thus will have a significant impact on several scientific and application domains including meteorology, oceanography, and flow visualization in applied fluid mechanics. The project gathers researchers from the fields of image analysis, computer science, applied mathematics, fluid mechanics and meteorology. The consortium is composed of three computer vision groups, a group involved in dynamic meteorology, a group specialized in the study of turbulent shear flows and a first rank company in the domain of flow visualization systems. The first objective of our proposal consists in studying novel and efficient methods to estimate and analyse fluid motions from image sequences. The highly deformable nature of the observed phenomena and the fact that theyare only partially observable raise difficult issues. Nevertheless, the huge amount of data available in the concerned domains (meteorology, oceanography, experimental fluid mechanics), and the mastering of generic mathematical frameworks to design sound image processing methods (variational methods, statistical models) will allow us to devise dedicated fluid motion image processing techniques integrating physical models/constraints derived from the laws of fluid mechanics. The second objective is to guarantee the applicability of the developed techniques to a large
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Breast self-reconstruction: The Promise of Breast Reconstruction with patients’ own tissue' (MATTISSE) targeting Horizon Europe.

assistant: **Abstract**

LATTICE MEDICAL develops MATTISSE, a fully degradable 3D printed breast implant allowing a natural and custom breast reconstruction in a single and simple surgery. MATTISSE technology uses a Tissue Engineering Chamber implanted in the former breast and made of 3D printed biocompatible and bioabsorbable polymer. MATTISSE regenerates autologous adipose tissue within 3-6 months, women recover a full breast in 18 months with a fully degraded implant at an affordable price and free from numerous surgical procedures. There is no longer any risk related to silicone implants thanks to the complete recovery with natural tissue. After validating the effectiveness of the MATTISSE medical device on animal models, this project aims at performing the mandatory clinical studies to launch the product on the EU market with the CE mark. A commercial team will be recruited to define and implement a marketing plan to ensure the success of MATTISSE. Lattice Medical plans to support 40000 women by 2030.


**Keywords:** Reconstruction,Bioprosthesis,Patient care,Medical devices
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Flight Centric ATC Project' (FCA) targeting Horizon Europe.

assistant: **Abstract**

The Flight Centric ATC project (FCA) addresses Industrial Research & Validation for Master Plan Phase C Connected and Automated ATM (HORIZON-SESAR-2022-DES-IR-01-WA6-1). The main objective of FCA is to finally develop (V3 Maturity level) the Flight Centric ATC concept for an ECAC-wide implementation in medium density traffic areas considering the existing national boundaries. Furthermore, the project includes the development of ECAC-wide deployment scenarios, which are consistent with the limitations of the VHF spectrum for voice communications. ECAC-wide benefits of the concept in each of the deployment scenarios will be analyzed as well, based on the exiting SESAR2020, PJ.10-W2-73 FCA Cost-Benefit Analysis. Two different exercises and workshops will be conducted during the project to address the remaining gaps and to take the final step from a V3 on-going solution to a V3 completed solution. Therefore, an analysis will be conducted to validate the Key Performance Indicators: Cost Efficiency (CEF2), Capacity (CAP), Predictability (PRD) and Fuel Efficiency (FEFF), as well as Human Performance and Safety. In addition, final validations will take place to validate e.g. the change from a sectorised airspace to Flight Centric ATC and vice versa, to assess the possibility of a fallback scenario, to evaluate an appropriate allocation strategy and an acceptable approach for the opening and closing of CWPs. The final results will be dissiminated across the relevant stakeholders and the S3JU via scientific papers, open days and a project website specificly designated to the Industrial Research Flight Centric ATC project.


**Keywords:** Flight Centric ATC, FCA, sectorless
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Environmental controls on mound formation along the european margin' in the context of a Fifth Framework call.

assistant: **Objectives**

Problems to be solved (while also addressing the relevant EU policies)Prominant carbonate mound reefs have been features of Earth's history ever since Cambrian times. These mounds frequently form giant host rocks for hydrocarbon accumulation. Their formation and environmental controls have not been discussed controversial, due to the absence of any modern analogue. The discovery of spectacular mounds along the European continental margin provides an outstanding opportunity to study the relevant processes of their formation. Data and observations on modern carbonate mounds are entirely missing. We want to know and define why, where, and by what means mound growth is favoured and are there specific paleoceanographic settings responsible that these living structures occur only along the European margin these days? Obviously, most of the carbonate mound regions known so far are very proximal to licensed hydrocarbon exploration blocks. Furthermore, they represent very special ecosystems, from which only very little is known up to now. However, they are already threatened by human activities such as deep-sea fisheries and hydrocarbon exploration and exploitation. Thus, the carbonate mound ecosystems deserve study and -where appropriate - selective conservation. (Sustainable Marine Ecosystems, Key Action 3.1.2)Scientific objectives and approachECOMOUND will investigate the morphology and setting, the oceanographic control, the role of biota, and the sedimentary processes of mound formation. During 5 cruises to the Porcupine Basin, the Rockall Basin, and the Trøms District off Norway, mapping of the mound arrangements (towed cameras, side scan sonar and seismic equipment) and measurements of the physical, chemical and oceanographic parameters will be carried out (moored current
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Building ecosystems of person-centered integrated care through co-creation' (BUILD) targeting Horizon Europe.

assistant: **Abstract**

The significant increase of the older (65+) European population with complex care needs calls for a better integration and coordination between health care and social services. Existing socio-economic and gendered inequalities in LTC might worsen in the future due to demographic ageing and austerity measures in LTC provision. So far, person-centered integrated care (PC-IC), as one solution to tackle these challenges, has mostly been developed in a top-down logic, and community engagement and participatory co-design have hardly been explored to develop PC-IC solutions. The aim of BUILD is to develop a framework and toolbox that assists policy makers in implementing participatory co-design and community engagement as methods to develop socially inclusive and sustainable PC-IC solutions for older adults with complex care needs that can be evaluated by the social return on investment. BUILD will increase the understanding of PC-IC by mapping and analyzing existing eco-systems of IC across Europe and identifying their corresponding regulatory frameworks and current challenges. BUILD will then go beyond these challenges by conducting a longitudinal, cross-national study that investigates care integration on a practical level, developing scientific evidence on how social inequalities shape the access to, and the outcomes of diverse forms of care and their integration while also highlighting the needs and required skills for PC-IC from the patients’ and caregivers’ perspective. Throughout the project, BUILD will involve communities, older adults with complex care needs, in-/formal caregivers, stakeholders and policy makers on different regulatory levels in the participatory co-design of PC-IC solutions and develop policy recommendations based on the experiences gathered. Ultima
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Noble metal nano-structures - Preparation using soft templates, characterisation and applications' (NANO-SOFT-2005) under Sixth Framework.

assistant: **Objectives**

The present project is aimed at imparting thorough training to the candidate in nanomaterials synthesis, characterisation and applications. We have recently adopted an innovative approach for the synthesis of noble metal nano structures having high catalytic activity for selective hydrogenation reactions using swollen mesophases of anionic surfactants as 'soft templates'. Two patents have been obtained for the works related to this. In the present project bi-metallic nano structures of Pt and Pd alloyed with transition metals and other noble metals will be prepared using cationic, anionic and non-ionic surfactants forming mesophases of different structures (hegagonal, lamellar or cubic). Radiolytic (gamma and electron beam) and chemical reduction methods w ill be used to reduce the metal ions in the mesophase.The mechanism of fast reduction reactions will be studied using unique ultra fast lasers at the state of the art facilities available in LCP called ELYSE. The novel nanostructures thus produced such as clusters, rods, wires etc. would be thoroughly characterised using most modern techniques such as TEM, HRTEM, STM, AFM, XPS etc. Their potential application as catalysts for selective hydrogenation, electro-catalysts for fuel cell reactions and hydrogen storage would be investigated in collaboration with academic and industrial partners. The electronic, optical and magnetic properties would be investigated during the re-integration phase in India. Thus the project is expected to increase our knowledge of t he formation of metallic nanostructures using 'soft templates', their morphology-activity relationship and novel catalysts for many industrial processes and fuel cell applications. The proposed project will not only empower the fellow to establish an independent re