RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The fun of gaming: Measuring the human experience of media enjoyment' (FUGA).

assistant: **Concept**

The main objective of FUGA is to create novel methods and improve existing measures in order to examine how the different dimensions of Computer Game Experience can be assessed comprehensively with high temporal resolution. FUGA will employ a broad variety of innovative techniques based on * laboratory and mobile psychophysiological recordings (i.e., facial EMG, EEG, ECG, EDA, and respiration), * functional magnetic resonance imagining (fMRI), * eye movement recordings, * the so-called (online) implicit association test, * tracking of behavioral indicators of emotion and motivation. An important objective of FUGA is to establish the construct validity, reliability, and predictive validity of the different Game Experience measures. A further objective is to develop a prototype of an emotionally adaptive game. The very first step is a conceptual clarification and dimensional modelling of Game Experiences, as well as the development of a theoretical framework describing the relationships between the relevant Game Experience dimensions and their potential measures. In the first set of empirical studies, the Game Experience measures will be construct validated against think-aloud and self-report methods as well as against each other. New ways to extract relevant parameters from the data will be examined and developed, and alternative data analytic techniques will be compared. This is followed by a second set of studies examining reliability of the measures. Finally, to establish the predictive validity of Game Experience measures, it will be examined how different emotional and cognitive responses or response patterns predict game play in the long run. The innovative measurement approach provided by FUGA can be applied when designing new digital games for different purposes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Innovation Management Capacity Enhancement of SMEs in Saxony-Anhalt (IMCESA)' to be submitted under Horizon 2020.

assistant: **Abstract**

The general objective of the described actions is to contribute to smart growth in the European Union by increasing the efficiency and effectiveness of investments in research, development and innovation and by contributing to a better and more efficient connection of actors along the innovation chain.The specific action will deliver services designed to ""Enhance the Innovation management capacity of SMEs"" by providing indepth support services to SMEs. Furthermore, beneficiaries of the SME Instrument under Horizon 2020 will receive specific targeted assistance to support coaching assignments addressing specific innovation weaknesses. To achieve the above mentioned objectives bottlenecks to the creation of economic impact in companies benefitting from grants by Horizon2020's SME instrument will be identified and these bottlenecks with the help of capable coaches addressed. This service to beneficiaries of the SME instrument in the context of a giving project is called 'Key account management'. In addition the efficiency and effectiveness of innovation processes will be increased in small and medium sized enterprises with significant innovation activities that could potentially become beneficiaries of European support to research and innovation but would not have effective access to consulting services for innovation management. This service, provided independently from a specific innovation project and focussing on a company's innovation management system, is called 'Enhancing the innovation management capacity of SMEs'.Direct impact from the two actions will be a significantly enhanced growth and profitability of SMEs receiving the services as compared to a control group. Innovation processes will be conducted more efficient and more effectively.Indirect impact will a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Multi-organic risk assessment of selected endocrine disrupters' (1998-2002).

assistant: **Innovation**

ED's with steroidal or anti-steroidal effects may be of great importance during embryonic development and later for metabolic, brain, cardiovascular, reproductive, and bone function. The effects of UV-absorbing chemicals (4-MDC, homosalate), characterised recently as estrogenic, and of Benzophenone D, a chemical used in cosmetics, as well as the fungicide Procymidone and the pesticide Linuron will be studied in rats and gene-targeted mice. High throughput methods to identify ED's with (anti) estrogenic (anti) androgenic, (anti) progestational, (anti) glucocorticoid, and (anti) thyroid hormone activities will be employed. Gene-targeted cell lines and animals, including the EU-sponsored EUROSTERONE DNA chip, will seek to quantify both ED's and their effects on gene and protein expression in different organs. This will lead to clear concepts for clinical trials towards the end of the project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Development of a Complete Triple Action Injectable Treatment for Osteoarthritis'.

assistant: **Objectives**

Osteoarthritis (OA) is an incurable complex disease affecting an estimated 240 million people globally including 40 million Europeans . OA is the fastest growing cause of disability due to an aging population and the obesity epidemic and affects more people each year than cancer and heart disease. In knee OA progressive degradation of bone and cartilage in the joint results in severe pain and reduced mobility. Current treatments for Knee OA target only one aspect of the disease, yet most recent scientific data highlight the need for multi-modal therapeutics to treat this complex disease.  Furthermore, the limitations of treatments force 80% of patients to rely on strong, addictive pain medication.  Through the Hydrolieve ERC proof of concept grant, it was proven that Hydrobloc, statistically significantly reduced pain sensations in an in vivo pain model.  These exciting results led Dr Alison Liddy to spin-out Relevium Ltd.Hydrobloc unique synergistic triple action addresses all aspects of this debilitating disease.  Hydrobloc is the only therapeutic that regenerates the damaged cartilage whilst providing immediate, superior pain relief, and improving the physical function of the joint through a cushioning lubricant effect. Pre-clinical studies have proven that Hydrobloc returns the OA joint to 90% of normal (non-OA) physical function.With this EIC grant, Relevium is partnering with NUI Galway to validate the pre-clinical results in larger animals and preclinically test for other OA indications. Relevium will compile the clinical trial dossier and develop a business model towards the maturation and transition to commercialisation.


**Keywords:** Orthobiologic, Osteoarthritis, Chronic Pain, Multimodal therapeutic, Cartilage Regeneration, Pain Relief, Lubrication, Knee os
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Archimedes 2001 - 'msc integrated industrial engineering'', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

This is an invention, which has been proven through a fully working prototype. Relating to orthopedic limb replacement research. Addressing the call for concepts to aid disabled people, especially those with upper extremity, hand-wrist replacements, or awaiting more permanent replacements. The gripper was originally intended for the food industry, developed at my placement company RHMTechnology. The gripper uses an arrangement of gears and spur tracks, to manipulate a flexible, central toroid, which is capable of providing the 'grip', without damaging the object being handled. So with delicate, organic and generally small objects in mind, it was thought that the prototype could be adapted for use in the upper-extremity limb replacement fields. A simplified version of the original robotic device, used for picking food was created, using a handheld arrangement.This hand version will then be adapted further for the specialist area of interest. See Fig.l and 3 in attachments.Application:- Application of the device to total loss of limb cases, due to trauma (bums, mine- detonation, accidents).- Use for partial loss victims - such that a 'replacement' would provide more function than the existing, 'dead limb'.- Implementation of the device, with the elder population, pediatric fields and the general population in mind.- Use of the device with myo-electrics and testing against current replacements.- Use of the device with the latest developments in the prosthetics field, which use pressure transducers in 'Sensory Feedback' limbs - which allow the user to know if they are passing something too hot to someone else. So feedback that allows the user to have greater sensitivity to the object.Areas of implementation- In industries employing large numbers of unskilled, manual workers
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project '6G Non Terrestrial Networks' (6G-NTN), addressing dissemination and exploitation.

assistant: **Impact**

The 6G-NTN project aims at researching and developing innovative technical, business, regulatory, and standardization enablers to achieve full and seamless integration of the Non-Terrestrial Network (NTN) component into the 6G system and establish the European leadership in this domain. The vision is to extend coverage, resilience, and sustainability of next generation mobile networks, meeting needs and expectations of both vertical and consumer market segments, while unleashing new value chains and creating broad societal impact. The proposed concept of full-fledged integration of the NTN component into 6G leverages multiple key project outcomes that will pave the way for a service roll-out in the 2030-35 time frame:- a sustainable and resilient 3D multi-layered (GSO, NGSO, HAPS, drones) network architecture.- a software defined payload adapted to all flying platforms and all frequency bands- a very low Earth orbiting space segment- a flexible waveform supporting terrestrial and non-terrestrial deployments.- the support of smart phones and vehicle/drone mounted terminals- the use of new spectrum (i.e. C and Q/V bands) in coexistence with the terrestrial network component - high accuracy and reliable positioning solutions.The newly designed NTN component will deliver: i.e. uRLLC (latency < 10 ms) and advanced eMBB (data rate up to several hundred of Mbps) services to vehicle, drone mounted ultra-small size devices, and battery activated nomadic terminals; ii. improved eMBB services to smartphones; iii. short emergency messaging services to smartphones in light indoor/in-vehicle environments; and iv. high accuracy (<10 cm) and reliable location service to both devices categories.By pulling together leading players across all involved industrial, research and innovation a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Stratification of Patients using advanced Integrative modeling of Data Routinely acquired for diagnosing Rheumatic complaints' (SPIDeRR).

assistant: **Innovation**

Globally 1.Globally 1.71 billion people have musculoskeletal symptoms, the leading contributor to disability. Early disease stratification is important to ensure appropriate care (most suited healthcare provider and best treatment choice). Currently the patient journey to diagnosis and effective treatment is long and inefficient, resulting in persistent disease burden and economical loss. This is due to insufficiently understood relations disease causes and similarities in symptoms between diseases, insufficiently distinguishing tests, trial and error approach in initial treatment.SPIDeRR aims to disentangle the real-life complexity of early diagnosis of rheumatic diseases by considering the complete web of factors influencing patients’ symptoms. SPIDeRR’s approach will go well beyond the state-of-the-art in the following ways:- By identifying different disease groups, requiring different therapies, amongst patients with similar symptoms in contrast to the traditional approach aiming to only capture one disease early. - By integrating all relevant data dimensions from every healthcare level (primary and secondary care and patients seeking advice online). - By translating and applying machine learning techniques from the “omics” field to clinical patient data, which will result in new pipelines for translational data science SPIDERR will deliver three clinical models -a symptom checker for patients -a decision support tool for (primary) care providers providing guiding additional examination and referral decisions-a patient-patient similarity network to optimise diagnostic groups in rheumatology and support treatment decisionTo achieve this we additionally deliver solutions for data integration and shared analyses though GDPR compliant digital research environment and fe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Parsing dopamine's learning and motor functions' (RegionalDopamine).

assistant: **Concept**

Appropriate selection of situation-appropriate behaviour requires both learning and motor control. Release of the neurotransmitter dopamine in the striatam is crucially involved in both of these processes. However, previous work investigated learning and motor functions of dopamine in isolation. To fully understand dopamine function and dysfunction, it is imperative to take both learning and motor control into account. Striatal dopamine release is thought to encode a reward prediction error, the discrepancy between expected and obtained outcome, as well as promote movement. Dopamine release optimises and drives behaviour by modulating the activity of striatal medium spiny neurons (MSNs) and their downstream neural pathways. Binding of dopamine to type-1 and type-2 dopamine receptor-expressing MSNs differentially modulate intracellular signalling cascades, increasing or decreasing phosphorylation of protein kinase A (PKA), respectively. Differential modulation of PKA activity is thought to underlie learning and motor control, ultimately driving behaviour. Importantly, dopamines influence on MSNs is functionally disparate between limbic, associative, and sensorimotor domains, and it is hypothesised that these regions differentially encode learning and movement. Here, I aim to discern the entanglement of dopamine functions by employing a powerful behavioural task that differentiates between learning and movement, while 1) simultaneously recording dopamine release in distinct striatal domains, and 2) recording the activity type-1 or type-2 MSNs using a novel, cutting-edge tool to detect real-time PKA activity. The complementary power of these innovations will enable me to drive forward the current understanding of dopamines function by combining state-of-the-art neuroscienc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Cascade rates of magnetohydrodynamic turbulence in the solar wind' in the context of a Seventh Framework call.

assistant: **Objectives**

Turbulence is one the most important unsolved problems of classical physics. Plasma occurs in states of turbulence under a wide range of conditions including space and astrophysical plasmas as well as those produced in laboratory confinement devices. Magnetohydrodynamics (MHD) is the simplest fluid approach to study plasma dynamics. MHD turbulence takes place in many practical applications (solar atmosphere, interstellar medium etc.). Due to this reason MHD turbulence has been intensively studied during the last several decades theoretically as well as by means of high resolution direct numerical simulations. Currently there exist more than ten different theoretical models of anisotropic MHD turbulence. With an abundance of in situ spacecraft measurements, the solar wind is a unique natural laboratory that can be used to test theories and improve our understanding of the basic mechanisms involved in MHD turbulence. Presented project implies the study of cascade rates in the solar wind turbulence using generalized Yaglom’s relation, for determination of the role of MHD turbulence in the solar wind heating, and for testing predictions of various theoretical models of MHD turbulence. The objectives of the presented project are: (i) Derivation of the generalized Yaglom’s relation for MHD turbulence taking into account the effect of expansion of the solar wind; (ii) determination of the role of MHD turbulence in the solar wind heating applying generalized Yaglom’s relation to the data of the solar wind fluctuations; (iii) determination of the relation between the energies and energy dissipation rates for the fast and slow solar wind data and comparison of the obtained results with the predictions of different theoretical model of MHD turbulence; (iv) to derive the analogue o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'High performance computing for wind energy', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Wind as a clean and renewable alternative to fossil fuels has become an increasingly important contributor to the energy portfolio of both Europe and Brazil. At almost every stage in wind energy exploitation ranging from wind turbine design, wind resource assessment to wind farm layout and operations, the application of HPC is a must. The goal of HPCWE is to address the key open challenges in applying HPC on wind energy, including efficient use of HPC resources in wind turbine simulations, accurate integration of meso- and micro-scale simulations, and optimization. The HPCWE consortium consists of 13 partners representing the top academic institutes, HPC centres and industries in Europe and Brazil. By exploring collaborations between Europe and Brazil, this consortium will develop novel algorithms, implement them in state-of-the-art codes and test the codes in academic and industrial cases to benefit the wind energy industry and research in both Europe and Brazil.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'The regulatory framework of globalisation: contents, instruments and agents. the need for an overall view.' in the context of a Fifth Framework call.

assistant: **Objectives**

The workshop aims to develop an overall approach for the establishment of an adequate regulatory framework for the global economy and related social issues. This overall approach should be interdisciplinary, address the different regulatory levels and cover he whole system of international agreements and organizations. To attain this goal, the workshop will put together high-level practititoners with a sound formation in social disciplines and academics that have been keen in studying the real functioning of political and legal institutions. The workshop should identify four interdependent sets of questions in which further research is needed:a) topics to be included in the regulatory framework;b) regulatory levels in which to deal with them;c) best type of rules to apply;d) mechanisms of enforcement of such rules. The workshop will also aim at consolidating a group of practitioners and academics sharing the same approach who