RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Ultrafast Control of Interlayer Coupling of Two-Dimensional Layered Materials', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Layered two-dimensional materials are novel quantum materials considered as the basis for future-generation electronics. The electronic and optical properties of such materials critically depend on so-called interlayer coupling – the interaction between the neighboring atomic layers within the material. What is of particular interest is that one can modulate this interlayer coupling, and thereby the material’s properties, by applying an electric field in the out-of-plane direction of the atomic layers. In this project, I focus on a typical semiconductor layered material called transition-metal dichalcogenides (TMDC). In TMDC, bandgap modulation with DC electric fields was recently achieved. However, the limitation of the modulation speed remains yet unclarified. In addition, the expected insulator-metal transition at the strong-field limit has not yet been realized because the required strong field causes a dielectric breakdown of the material.This project aims to (1) Realize ultrafast control of electronic properties of layered materials via direct ultrafast manipulation of interlayer coupling, (2) Identify the speed limitations to this controlling mechanism, and (3) Realize the insulator-metal transition in the layered material via the ultrafast control scheme. To investigate the ultrafast dynamics, I will utilize the terahertz technology, which enables us to apply a very short pulse of an electric field - a terahertz pulse - to the material and observe the change of its optical properties in an ultrafast timescale. A newly proposed micrometer-sized device, which converts an incident terahertz pulse to a strong out-of-plane electric field on TMDC, will enable ultrafast property control.The proposed scheme will be applicable for the ultrafast control of quantum phases
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'QSAR computational models' self-using platform for EC Regulation-REACH' (QSAREACH), addressing dissemination and exploitation.

assistant: **Impact**

Chemicals substances are presented in daily life like cosmetics, functional food or agro-industry. The EC Regulation1907/2006 for Registration, Evaluation, Authorization and Restriction of Chemicals (REACH), for the production and use ofchemicals when they are produced/imported in/to Europe in an amount greater than 1 ton/year has two major and clearcustomer paint points: first, REACH implies very high costs due to the experimental and administrative work required, whichrepresents a particularly sensitive issue for SMEs. Second, REACH implies the need for a huge number of animal tests todemonstrate the safety of chemicals under approval. Animal experiments require much time for preparation and execution,and are expensive and ethically questionable. Instead, QSAR computational models represent significant savings in time,resources and money, since the applicability of predictive models is ease and immediate. And this business need from theEuropean chemical industry SMEs is our market opportunity, by the final development of a novel high scalable technologicalplatform of easy access to experienced and non-experienced end-users. These platform will include QSAR models of(eco)toxicology of chemicals -including nanomaterials (NMs)- to comply with the strict EC Regulation, where assays withanimals in some specific domains, such as cosmetic, are completely forbidden. This customer self-using platform will includean additional tool for the evaluation of the appropriateness of replacing the chemicals studied for alternative compoundswhich a safer (eco)toxicological profile. ProtoQSAR is a five years’ company that arises from more than fifteen years ofactivity and experience of its team members, both academic and industrial sides, currently providing consulting servicesrelated to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Hydrocolloids as functional food ingredients for gut health'.

assistant: **Concept**

The overall aim of the project is to realize a commercial opportunity to produce low molecular weight polysaccharides (LMWP) from alginate- and agar-bearing seaweeds for applications in food & health, and wellness products by a group of SMEs. The aim will be addressed by an integrated workplan comprising 1 management activity 5 interlinked RTD workpackages, and a dissemination and exploitation activity. In the RTD programme, Cybercolloids (CC) will produce and characterize 8 novel, LMWPs from alginate and agar raw materials provided by 2 SMEs - ROKO (RO) and Hebridean Seaweed (HS). The LMWPs will be screened using batch culture fermentations with human faecal bacteria, for prebiotic activity (i.e. ability to modulate beneficially the gut microflora) by University of Reading (UREAD). The 2 most effective agar and alginate LMWPs will be selected and bulk produced by CC for validation of prebiotic activity in a feeding trial in human volunteers (University of Ulster)). The end points to be assessed will be stimulation of beneficial bacteria (bifidogenic effects), increased short chain fatty acid production, beneficial effects on stool formation, and improvements in gut barrier function (assessed by an in vitro method). Additionally, benefits of the LMWPs towards plasma lipid profiles and blood glucose levels will be assessed. Alongside the human study, a detailed investigation of the effects of the selected LMWPs in an in vitro model of the human colon will be conducted by UREAD to provide supporting evidence for beneficial effects on bacterial types and activities in the colon. RO and HS in conjunction with CC will implement LMWP technology transfer and scale-up to facilitate production at an industrial scale. Subsequently, another SME Marigot Ltd, will provide a route to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Alliance Permanent Access to the Records of Science in Europe Network' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Digital preservation offers the economic and social benefits associated with the long-term preservation of information, knowledge and know-how for reuse by later generations. However, digital preservation has  a great  problem,  namely  that preservation support structures are built on projects which are short lived and fragmented. The unique feature of the APARSEN network is that it is building on the already established Alliance for Permanent Access (APA), a membership organisation of major European stakeholders in digital data and digital preservation. These stakeholders have come together to create a shared vision and framework for a sustainable digital information infrastructure providing permanent access to digitally encoded information.<br/>To this self-sustaining grouping APARSEN will bring a wide range of other experts in digital preservation including academic and commercial researchers, as well as researchers in other cross-European organisations. The members of the APA and other members of the consortium already undertake research in digital preservation individually, but even here  the effort is fragmented despite smaller  groupings of these organisations working together in specific EU and national  projects. APARSEN will help to combine and integrate these programmes into a shared programme of work, unified in a common vision, thereby creating the pre-eminent Virtual Centre of Excellence in digital preservation in Europe, if not the world. The APA provides a natural basis for a longer term consolidation of digital preservation research and expertise.<br/>The Joint Programme of Activity will cover: technical methods for preservation, access and most importantly reuse of data  holdings  over the whole lifecycle; legal and economic issues including costs a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Astrophysical probes of fundamental physics' (1994-1998).

assistant: **Innovation**

Research objectives and content The primary objective of this project is the study of the implications for particle physics of experimental data on GRBs (gamma-ray bursts). In particular, in light of their high typical energies, small-scale time structure and cosmological origin (which has been very recently established experimentally), GRBs might allow to test the possibility of 'wave dispersion in the quantum-gravity vacuuum' which has recently emerged in two quantum-gravity approaches: the 'Liouville String' approach of Ellis et al, and the approach based on dimensionful deformations of Poincare' symmetries proposed by Lukierski et al. Bounds on the magnitude of this quantum-gravity effect will be derived using GRB data presently available. In addition, the most popular GRB models will be examined with the objective of establishing how the predictions of these models would be affected by the above mentioned wave dispersion, also hoping to provide useful information to the experimentalists who might attempt to exploit the sensitivity of GRBs to this type of quantum-gravity physics. Training content (objective, benefit and expected impact) My studies of the interface between particle physics and astrophysics/cosmology (which started as part of the work for my Ph.D. thesis) have been mostly focused on rather formal/mathematical aspects, e.g. I contributed to the development of a formalism for the analysis of the effective potential relevant for the investigation of certain early-universe phase transitions. Stimulated by the findings of some of my most recent studies, most notably a work in collaboration with Ellis, Mavromatos, Nanopoulos and Sarkar, I am determined to shift the emphasis of my work toward more phenomenological aspects of 'astroparticle physics.' The oppo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Trends on educational inequalities over time and successful interventions that contribute to reverse them' (REVERS-ED) targeting Horizon Europe.

assistant: **Abstract**

Research through the decades has demonstrated the existence and persistence of educational inequalities. These inequalities particularly affect vulnerable groups of students such as those with low socioeconomic status or a migratory history, who more frequently show high rates of early school leaving and low school performance. However, there is increasing scientific literature which identifies educational interventions that are effective in compensating for these inequalities, overcoming deterministic analyses in the understanding of the educational trajectories of vulnerable children and youth.  Taking this into account, this project will have a double approach. On the one hand, the project will exploit the large volume of existing educational data at the national and regional levels to map and analyse educational inequalities from a longitudinal perspective, identifying key features and trends. For the analysis, retrospective cohort studies will be conducted to understand how educational inequalities have evolved in recent years and how they relate to characteristics of the education received. On the other hand, the existing interventions that compensate for these inequalities will be studied in depth. Longitudinal analysis (quantitative and qualitative) will be performed of the educational trajectories of children and youth who have participated in successful educational interventions already identified by scientific research, to better understand how and to what extent they contribute to improve learning outcomes. With these analyses, this project aims to facilitate that effective interventions can be translated into policies and replicated to advance into more inclusive educational systems with better learning outcomes for all. Additionally, the project will allow
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Developing First-in-Class Diamond-based Quantum Microscopy for immediate semiconductor industry applications' (DIAMONIQ) under Horizon Europe.

assistant: **Objectives**

Semiconductors are an essential component of modern electronics. The miniaturization of semiconductors has been a key driver of technological innovation. However, as semiconductor technology continues to advance, the available quality control methods, such as thermal imaging or voltage alteration measurements, become insufficient. Diamond-based quantum sensing has the potential to answer the need for precise diagnostics of detecting magnetic field alterations caused by chips defect. But available implementations suffer from a tradeoff between speed and imaging resolution.At QuantumDiamonds, we overcome these challenges and developed a Super-resolution Quantum Imager (SQI) that combines advanced optical components with proprietary diamond production and software. Our system enables imaging at sub-100 nm resolution and fast measurement in the range of minutes. In this project, we will test it with actors from the semiconductor industry and prepare our system for commercialization.


**Keywords:** Quantum, quantum sensing, diamond sensors, magnetometry, quantum microscopy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Stress cascades and Alzheimer's disease'.

assistant: **Concept**

Global increases in lifespan make the challenge to prevent and treat Alzheimer’s disease (AD) urgent. While the etiology of non-familial/sporadic AD is largely unknown, many AD patients have elevated stress hormone (glucocorticoid, GC) levels and recent animal studies show that high GC levels promote production of amyloidogenic peptides (key pathogenic players in AD) in association with memory deficits. Stress/GC are implicated in mood and cognitive disorders, and meta-analyses identify depression (often associated with cognitive deficits) as a risk for AD. This, and the fact that depression and AD involve similar limbic-cortical substrates, suggests shared spatio-temporal trajectories, with the two conditions representing early and late manifestations of increased amyloid beta (A-beta) levels. This proposal aims to i) define the spatio-temporal progression of the impact of stress on A-beta production based on morphochemical (immunochemical, gene expression, morphometric) mapping; and ii) identify the cellular targets and molecular mechanisms through which stress is pro-amyloidogenic (multiplex qPCR, Western blot, enzymatic activity assay). Two transgenic mice (arcAbeta and RiboTag mice) of different ages and sexes (women are more prone to AD and depression) will be used.  Analysis of cellular events in genetically-marked (RiboTag) neuronal sub-populations adds innovative value. The applicant will apply his existing skills in structural and behavioral neurobiology, complemented by additional (primary neuronal culture, molecular and cellular neuroanatomy) and state-of-the-art methodologies (high-speed voltage-sensitive dye imaging and optogenetics), acquired at the host institute. Besides offering technical and generic skills, the host institute allows dialogue between b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Sensitive, specific high-throughput plasma proteome analysis via ProteinSeq' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Despite increasing interest in biomarkers to diagnose and distinguish diseases and select treatment few new protein biomarkers are being successfully validated. Important explanations for the limited success are poor specificity and sensitivity of detection of plasma proteins using current assays, and inability to analyze large numbers of markers and samples.  Improved assays should provide access to plasma protein biomarkers at levels below current detection thresholds, potentially reflecting disease processes anywhere in the body at early stages. They should also distinguish closely similar protein variants. The assays should furthermore assess numerous markers in parallel with limited consumption of biobank samples.The aim of this project is to enable investigations of protein biomarkers at entirely new levels of performance. The basis of the proposal is our expertise in molecular tools and specifically an approach to protein analysis that addresses the above requirements.This technology is now ready to be scaled for large-volume, high-performance assays with the following characteristics: 1) Unsurpassed specificity via simultaneous detection of three epitopes on any target protein. 2) Amplifiable DNA strands form upon specific detection, permitting ultrasensitive detection. 3) Only appropriate reagent combinations result in amplifiable reporter strands, overcoming obstacles to multiplex protein detection. 4) Tag sequences in the amplified DNA strands identify the detected proteins and the investigated samples, allowing digital information of protein abundance to be retrieved via next generation DNA sequencing of multiplex reactions for large numbers of patients in single runs.I propose to set up and apply assays of a thousand proteins in parallel in small plasma sam
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how '#NitRecerCat: The Catalan European Researchers' Night""' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The Catalan European Researchers’ Night project consists in a two years proposal for 2024 and 2025. The overall proposal is centred on two main activities: The European Researchers’ Night (ERN) and Researchers at Schools (R@S). The well-known ERN will be held on 27 September 2024 and on 26 September 2025. During two years, nine partners will bring research and researchers closer to more than 30,000 people and, 10000 students with nearly 500 activities which will be performed all throughout Catalonia. A part of ERN, Researchers at Schools (R@S) are designed, adding a much better and longer interaction of pupils with the research from the Catalan institutions. 15 schools will become #NitEduCat Schools, with two-years of stable collaboration between a team of researchers and the schools. The proposal aims at making the public aware about the present mission-oriented program of European Commission, mainly in the idea of how Researchers can help to change the world to a better one. #NitRecerCat is divided in two activities:•Catalan European Researchers’ Night (Nit Europea de la Recerca, ERN)o“La Nit Catalana de la Recerca” – More than 250 activities for each edition are programmed during Friday evening/night. A common “El Racó d’Europa” will be allocated in each location together with Women in Science exhibition.o“Ensopega’t amb la Recerca” – During Friday/Saturday morning, research will be found in everyday locations, from markets, to museums, malls, bars, etc, •Researchers at School – (R@S) oNitEduCat Schools –Development of 5-medium-long-term projects that promote stable collaboration between a team of researchers and primary/secondary school. o“La Recerca va a l’Escola” – Special campaigns will be done for Research visiting School. Researcher will encourage students to f