RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'European (euro) network for development of novel safe vaccines based on new generation amplicons (amp) and other defective hsv-1 derived vectors as foreign antigen delivery systems.' in the context of a Fifth Framework call.

assistant: **Objectives**

Seven European laboratories have associated to evaluate the potential of defective HSV vectors, including helper-free HSV amplicons, as vaccine for the delivery of foreign antigens. The model antigens will be derived from human viruses of high public health concern, such as HCV, HIV-1 and HPV-16, each causing significant morbidity and mortality and substantial economic burden. No effective vaccines are available to prevent or treat these viral infections. To this end we plan to determine the conditions required to optimise delivery, expression and presentation of foreign antigens, including the in vivo synthesis of empty virus-like HCV and HPV-16 particles. Significant innovations will be the use of a unique in its nature vector (the amplicon), never used before, as vaccine vector and the attempt to manipulate the immune response by attracting monocytes to sites of infection and inducing their differentiation into dendritic cells.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Awareness action for business best practice integrating information technologies in industrial SMES in southern regions of Europe' (ABUITSS) under Fourth Framework.

assistant: **Objectives**

The ABUITSS project aims to increase the awareness of Business Process Orientation (BPO), Business Process Re-engineering and its Information Technology support among the industrial SME community of Southern Europe. ABUITSS is a TBP Dissemination Action addressed to the Domain 7 of the Esprit Programme.This project development will be based on the experience of the consortium partners and the results of previous EC projects which have highlighted great differences regarding TBP awareness between Southern Europe and Central & Northern Europe. These projects (PEPITA and COBRA), have also shown an important lack of awareness between SMEs in these regions and a different perception of real needs (metrics, methods, processes, etc;) between technology providers & consultants and end users. At the same time, there exists great expectations on BPO and IT for improving business practices in the target SMEs audience.ABUITSS will carry out three activities in parallel; a survey and analysis to determine properly the understanding of the users concerning TBP (1000 SMEs will be mailed), an awareness action of BPO, BPR and TBP by developing and organising a set of training seminars (6 training seminars will be held), and a dissemination activity of the results of the ABUITSS analysis and other current TBP pilots of previous Esprit calls.The dissemination activities will be also supported including the results of the TBP analysis in the CORDIS database, letting the Value Relay Centre Network know what is available, providing these results to the TBP Networks to be built up in Esprit, and by organising 4 workshops in Southern countries.The consortium is composed of 4 partners from 5 different Member States with significant experience in TBP, dissemination and awareness actions and surv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Exploring the Interface Between Ionic Liquids and Graphene : Elucidating Structure and Electronic Properties' under Horizon 2020.

assistant: **Concept**

GRAPHIL aims at generating a detailed picture of the lateral nanostructure of the ionic liquid (IL)-graphene interface. A special focus will be given to the understanding of the IL-graphene interactions that generate the interfacial structure and to the influence of IL on graphene electronic structure. This understanding will greatly benefit the research on IL/graphene based energy storage devices.State-of-the-art amplitude-modulated atomic force microscopy (AM-AFM) will be employed to visualize the lateral arrangement of cations and anions for a series of ionic liquids in order to establish the correlation between the constituent ions and the interfacial structure of IL on graphene. The structure will be compared for biased as well as unbiased graphene substrates. Raman spectroscopy will be used to establish the dependence of IL structure on the electronic structure of graphene. This highly interdisciplinary research that lies at the interface of chemistry, material science and surface science will be carried out at KU Leuven-University of Leuven (experimental work, in the group of Prof. Steven De Feyter) and will be complemented by theoretical simulations carried out at University of Mons (in group of Prof. Roberto Lazzaroni) and University of Antwerp (in the group of Prof. Francois Peters)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Novel treatments for the mucus accumulation at chronic lung diseases' (MUC2GO) targeting Horizon Europe.

assistant: **Abstract**

The aim of this proof of concept is to develop novel therapies based on the discoveries made during the AdvERC grant on mucus and mucins in the lung and intestine. The discovery that the XX protein is absent or almost absent in healthy individuals and animals and heavily increased in human COPD and induced lung disease in animals made us study this. During the ERC grant we  discoverd that XX is anchoring and attaching the lung mucus by forming a cap on the accumulated mucus. In the absence of  XX the mucus is non-attached and transported even better than normal. We have now determined the detailed molecular structure of the XX and learnt how this protein can form long, large polymers by non-covalent interactions. We will now develop inhibitory peptides, proteins, antibodies or small organic molecules to be used as therapeutic drugs for detaching the attached mucus at Cystic Fibrosis, Chronic bronchitis, COPD, and other lung diseases with mucus accumulation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Economic analysis of certification systems for organic food and farming' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

With the ongoing growth of the organic sector and the spread of organic production across the EU, the field of organic certification has become a maze of competing labels and logos, involving different private and public standards, in addition to European law. This diversity reflects the specific conditions for organic operators in countries or regions but can also lead to confusion for both producers and consumers and may create a variety of costs. Reg. (EC) 834/2007 intends a review of the revised regulation by the year 2011. It is imperative to conduct a comprehensive economic analysis of the variety of existing certification systems and their impact on the internal market for organic goods. This project proposes to combine the experience and knowledge of both researchers and SMEs to fulfil the following objectives: analyse the implementation of organic certification systems and estimate all relevant expenditures or transaction costs for different certification systems along the organic food supply chain in various regions of the EU, including a candidate country and Switzerland. It will involve stakeholders. Access to the necessary data has already been agreed with the involved partners or appropriate agencies for all seven study countries. In addition to costs, benefits of certification will be analysed, using data on consumers' recognition, image and willingness to pay for different organic logos and trademarks, with their underlying production standards and certification procedures. The project will consider consumer and certification issues equally. Economic models will be applied to analyse the determinants of costs and benefits, as well as provide recommendations for the development of risk-based certification systems. Finally, recommendations will be drawn fo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Mumps VIRus EXploitation of the human adhesion receptor GPR125' (VIREX) targeting Horizon 2020.

assistant: **Abstract**

Mumps virus is a re-emerging pathogen that causes painful inflammatory symptoms, such as parotitis (salivary gland infection) and orchitis (testis infection). It is highly neurotropic with evidence of brain infection in half of cases and clinical evidence in up to 10%. It is a small RNA virus belonging to the family of paramyxoviridae that includes e.g. viruses for measles and pneumonia, all having a huge impact on global economics and human health. Current vaccine programs have not managed to eliminate mumps and infections occur also in vaccinated individuals. Seven transmembrane (7TM) receptors are important drug targets. Large DNA viruses (herpes- and pox-) assign large parts of their genomes to exploit 7TM receptors. No such mechanism has however yet been described for small viruses. Based on strong preliminary data, I will in this interdisciplinary project test the groundbreaking hypothesis that the adhesion 7TM receptor GPR125 is central for the organ damage caused by mumps virus via an interaction with the mumps virus-encoded short-hydrophobic (SH)-protein. I will do so by determining:1 - The functional consequences of GPR125-SH-interaction at a single cell, organ and whole body level within the context of mumps virus infection2 - The structural requirements for the GPR125-mumps virus interaction using NMR and resolution of crystal structure in preparation for future drug design The project is high risk and high gain, yet the gain clearly exceeds the risk. On account of my past expertise in pharmacology and virology, and that of several expert collaborators, the project is indeed feasible. It has tremendous perspectives as SH-proteins are present also in other viruses. The SH-GPR125 complex might thus represent a general principle for organ damage and a mode of a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Syzygies, moduli and topological invariants of groups'.

assistant: **Innovation**

This is a proposal aimed at harvesting interconnections between algebraic geometry and geometric group theory using syzygies. The impetus of the proposal is the recent breakthrough in which, inspired by rational homotopy theory, we introduced Koszul modules as novel homological objects  establishing striking connections between algebraic geometry and geometric group theory. Deep statements in geometric group theory have startling counterparts in algebraic geometry and these connection led to a recent proof of Green's Conjecture for generic algebraic curves in arbitrary characteristic, as well as to a dramatically simpler proof in characteristic zero. Based on a dynamic view of mathematics in which ideas from one field trigger major developments in another, I propose to lead a group at HU Berlin dedicated to the following major themes, which are outlined in the proposal: (i) Find a solution to  Green's Conjecture on the syzygies of an arbitrary smooth canonical curve of genus g. Find a full solution to the Prym-Green Conjecture on the syzygies of a general paracanonical algebraic curve of genus g. Formulate and prove a non-commutative Green's Conjecture for super algebraic curves. (ii) Compute the Kodaira dimension of the moduli space  of curves in the transition case from unirationality to general type, when g is between 17 and 21. Construct the  canonical model of the moduli space of curves and find its modular interpretation. (iii) Find algebro-geometric interpretations for Alexander invariants of the  Torelli group of the mapping class group and that of the Torelli group of the free group. Understand the link between these invariants, the homotopy type and the cohomological dimension of the moduli space of curves. (iv) Get structural insight in the newly discovered t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'CO-OPERATIVE ROBOT APPLICATION IN THE TEXTILE INDUSTRY FOR FANCY YARN MACHINE'.

assistant: **Objectives**

Textile industry is one of the largest industries in the world. To sustain its commercial success it becomes imperative to produce goods of high quality at reasonable prices to achieve customer satisfaction, which asks for continuous modernization of the textile machines.Each step towards innovation means streamlining activities with a versatile approach to minimize the manpower in the intensive and repetitive jobs. It is expected to have an incremental level of automatization in the textile industries implemented with human-robot collaborative models, where humans are doing “customization” tasks.CORTI project idea was born with the aim to facilitate the introduction of collaborative robot in the spinning area of the textile industry with a special outlook, at this stage, to the fancy yarn machines designed, produced and selled by Gualchieri&Gualchieri.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The European Social Survey - Data for a Changing Europe' (ESS-DACE) targeting Seventh Framework.

assistant: **Abstract**

ESS-DACE aims to secure the continuation and consolidation of the European Social Survey (ESS) as a key data source for measuring and understanding long-term changes in public attitudes across Europe. This will be achieved by strengthening the links between the 7 institutions responsible for the central design and coordination of the ESS infrastructure, as well as between the ESS and its funders, data users, national teams and a distinguished network of advisers. The objectives of the ESS infrastructure are: to chart and explain changes in Europe’s social, political and moral climate (WP2, WP4); to achieve and spread improved standards of rigour in cross-national social measurement, and simultaneously to raise the threshold standards of national surveys (WP3, WP5, WP7, WP12); to introduce and encourage the use of soundly-based attitudinal indicators of national progress, based on citizens’ judgments of key aspects of their societies (WP6); to undertake and facilitate the training of European researchers in comparative quantitative measurement and analysis (WP9); to provide enhanced access remotely to the users of and participants in the infrastructure (WP8); to improve the visibility and outreach of quantitative data on social change to academics, policy makers and the wider public (WP5, WP10, WP11); to maintain and update a specially-created ‘contextual’ data repository to help isolate the independent effect of background political and social developments on shifts in attitudes and values (WP13) and to refine the financial, operational and organisational arrangements of the ESS infrastructure to suit its longer term perspectives and commitments (WP3). This application is to ensure not just the survival of the ESS time series, but also to consolidate its achievements by
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Mapping functional protein-RNA interactions to identify new targets for oligonucleotide-based therapy.' in the context of a Seventh Framework call.

assistant: **Objectives**

An important question of modern neurobiology is how neurons regulate synaptic function in response to excitation. In particular, the roles of alternative pre-mRNA splicing and mRNA translation regulation in this response are poorly understood. We will study the RNA-binding proteins (RBPs) that control these post-transcriptional changes using a UV crosslinking-based purification method (CLIP) and ultra-high throughput sequencing. Computational analysis of the resulting data will define the sequence and structural features of RNA motifs recognized by each RBP. Splicing microarrays and translation reporter assays will then allow us to examine the regulatory functions of RBPs and RNA motifs. By integrating the biochemical and functional datasets, we will relate the position of RNA motifs to the activity of bound RBPs, and predict the interactions that act as central nodes in the regulatory network. The physiological role of these core RBP-RNA interactions will then be tested using antisense RNAs. Together, these projects will provide insights to the regulatory mechanisms underlying neuronal activity-dependent changes, and provide new opportunities for future treatments of neurodegenerative disorders.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Filamentous fungi as cell factory for the production of industrial importation products' in the context of a Fourth Framework call.

assistant: **Objectives**

Filamentous fungi have been successfully exploited for many years by the European fermentation industries for the production of both low molecular weight products such as organic acids, antibiotics, carotenoids and high molecular weight products including a broad spectrum of fungal enzymes. To improve the efficiency of production and quality of these compounds, and to produce new industrially important products, it is necessary to understand the biological details of why fungal cells are productive and to design efficient and reliable industrial processes based on the concept of utilising FILAMENTOUS FUNGI AS CELL FACTORIES. This research proposal describes a highly coordinated and inter- dependent research programme with the general objective of investigating the biological and biochemical engineering components of the Filamentous-Fungal Cell Factory. Research effort is focused on the following main objectives: 1) to extend our knowledge of the genetics and cell biology of fungi to facilitate the design of fungal cells able to carry out industrially important processes; 2) to characterize metabolic pathways and fluxes, to model metabolism, identify bottlenecks and subsequently redesign and engineer metabolism; 3) to improve the efficiency of protein production and the quality of the product; 5) to characterize and subsequently manipulate secondary metabolism and to establish its interaction with primary metabolism; and 5) to develop continuous flow and fed-batch culture fermentation protocols that optimize the production of proteins. During the programme the following key issues will be studied and improved: i) nutrient uptake and signal transduction; ii) control of gene- expression; iii) primary metabolism and metabolic flux engineering; iv) secondary metabolism, meta