RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Elucidation and characterisation of epithelial cell phenotypes' under Fifth Framework.

assistant: **Concept**

A key factor in the pathogenesis of several clinically important diseases is epithelial cell dysfunction. This proposal will investigate novel areas of epithelial cell biology with the aim of enhancing our understanding of the role of epithelial cells in the development and progression of chronic dermal wounds, COPD/asthma and endometriosis. Project 1 will investigate the role of retinoid receptor agonists on epithelial cell phenotype during dermal wound healing. The project will characterize retinoid receptor expression in primary human keratinocytes before and after mechanical injury. Subsequently, the study will investigate retinoid mediated gene expression in both in-vitro and in-vivo wound models. Project 2 will study the role of estrogen on endometrial cell function at a molecular level. This project will identify biomarkers of estrogen function in endometrium in-order to expand understanding of how estrogen mediated gene regulation impacts on endometrial estrogen response. Project 3 will investigate the responses of lung epithelial cells following allergen or bacterial challenge in-vitro. The project will identify changes in gene expression after exposure to house dust mite and H. influenzae, and investigate links with the release of key cytokines. Projects will employ state of the art micro-array technology (which is not available in most academic institutions) in-order to develop understanding of epithelial cell gene expression in a number of biological paradigms.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Monte-Carlo studies of protein-induced curvatures of bilayer membranes 5' in the context of a Fourth Framework call.

assistant: **Objectives**

The aggregation process of amphiphilic molecules, such as surfactants a lipids, into micelles, bilayers, vesicles and biological membranes, and the interaction between them, is involved in the most common cellular activity. One of the major challenges is to understand the structural aspects that lead to the formation of the most favoured structure under molecular geometry and packing constraints considerations that minimizes the interfacial energy per molecule. Particularly, the curvature of the vesicles, or lipid bilayers, can be regulated by altering the ratio of the different lipid types that can pack together. Therefore, when protein molecules are incorporated into these structures often result in a preferential clustering of specific lipids around a protein.  Our purpose is to study the effects of membrane proteins on the curvatu of bilayer membranes. In particular, we will consider two cases: (1) Does a bilayer membrane change its local curvature at the particular site, where a single protein is inserted into the membrane?. How is the geometry of the protein related to a successful local bending of a membrane?. What are the relevant forces for this process? (2) What are the relevant forces leading to aggregation of proteins and the subsequent induced curvature of the bilayer?. Is aggregation driven by the development of curvature?. How does the process of a protein-induced curvature of a bilayer differ from that of a monolayer ?
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Artificial Neural Networks for the Prediction of Contrails and Aviation Induced Cloudiness' (E-CONTRAIL).

assistant: **Innovation**

Contrails and aviation-induced cloudiness effects on climate change show large uncertainties since they are subject to meteorological, regional, and seasonal variations. Indeed, under some specific circumstances, aircraft can generate anthropogenic cirrus with cooling. Thus, the need for research into contrails and aviation-induced cloudiness and its associated uncertainties to be considered in aviation climate mitigation actions becomes unquestionable.We will blend cutting-edge AI techniques (deep learning) and climate science with application to the aviation domain, aiming at closing (at least partially) de existing gap in terms of understanding aviation-induced climate impact. The overall purpose of E-CONTRAIL project is to develop artificial neural networks (leveraging remote sensing detection methods) for the prediction of the climate impact derived from contrails and aviation-induced cloudiness, contributing, thus, to a better understanding of the non-CO2 impact of aviation on global warming and reducing their associated uncertainties as essential steps towards green aviation. Specifically, the objectives of E-CONTRAIL are:O-1 to develop remote sensing algorithms for the detection of contrails and aviation-induced cloudiness.O-2 to quantify the radiative forcing of ice clouds based on remote sensing and radiative transfer methods.O-3 to use of deep learning architectures to generate AI models capable of predicting the radiative forcing of contrails based on data-archive numerical weather forecasts and historical trafficO-4 to assess the climate impact and develop a visualization tool in a dashboardUpon successful achievement of the objectives described above, we ambition to provide aviation stakeholders with an early and accurate (thus, reducing the associated unc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The Smartphone Payment Scheme for Europe' (Bluecode), addressing dissemination and exploitation.

assistant: **Impact**

Cash has been the most popular payment method for centuries, but it is quite cumbersome and expensive. Decades ago, the payment possibilities were broadened with cheques and debit/credit cards, and recently a new generation of alternatives brought by FinTech companies is disrupting the industry with eWallets, contactless payment, etc. However, most of these new payment tools inevitably involve resorting to USA-based card networks (Visa and MasterCard) and electronic payment tools (PayPal, Apple Pay, Google Wallet). This represents a dramatic situation for the European financial industry, threatened to lose the revenues generated by the transactions but also the ‘emotional’ link with customers and even the whole payment process (consumers migrating to USA banks). How can we help tackling this challenge? Blue Code is an innovative mobile payment solution that will avoid the need of resorting to USA players to conduct the non-cash payments in Europe. Through our 100% European payment scheme, the entire payment process is conducted with European entities, so all the revenues and customer interface remains internally. Besides, we assure ‘security by design’ through an innovative payment method based on barcodes (Tokens) that keeps all the process anonymous, so no sensitive data like name, address or bank account is managed, and thus there are no possibilities of hacking of misuse. In Europe, 130 billion non-cash transactions are performed each year and this number is growing 6.5% annually. The alternative payment methods like Blue Code are increasing its relevance and are estimated to process 20% of the total cashless transactions by 2020, taking one third of the total revenues generated, thus a total addressable market of €22 billion. Thanks to the technical advances and co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'COpernicus Applications and services for Low impact agriculture in Australia' (COALA).

assistant: **Innovation**

COALA will develop Copernicus-based information service for irrigation and nutrient management for the Australian agricultural systems, starting from the consolidated past experiences of the proposed European partnership, but based on strong collaboration with Academic Australian institutions and business players in the agricultural sector of Australia. Operational farming advisory services will be further developed on one hand to include nutrient managements on the other to provide water accounting data from the farm to the district and/or basin scale. COALA will monitor crops development, water and nutrient status, irrigated areas by means of innovative algorithms based on Sentinel Earth Observation data, which will be accessed by means of the new cloud platforms (DIAS) of Copernicus. In-situ and other source of data will be used to improve the accuracy of the products for the final users, which will be on three different levels: i) farmers, ii) irrigation infrastructure operators, iii) basin authorities. COALA will demonstrate that Copernicus data and new DIAS infrastructure can greatly improve the availability of information for management decisions on irrigation and nutrient management at all decision levels, from the Water Authority in charge of monitoring the implementation of the basin exploitation plan, to the farm level, passing through the irrigation infrastructure operators, in charge of managing irrigation distribution infrastructures. COALA tools and data will improve the decision making and policy for sustainable use of water and nutrients in multi-functional ecosystems. Through this project, it will be possible to explore new business opportunities in Australia for the European industry of Earth Observation services.


**Keywords:** DIAS, AUSTRALIA, CROP
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'European fleet for airborne research in the field of environment and geo-sciences' (EUFAR).

assistant: **Concept**

EUFAR is an Integrated Infrastructure Initiative that brings together 22 leading European institutions and companies involved in airborne research, operating 23 instrumented aircraft. EUFAR, being a user-driven project, aims at: * co-ordinating the networ k for exchanging knowledge, sharing developments, and building the unified structure that is required for improving access to the infrastructures; * providing users with Transnational Access (TA) to the infrastructures; * extending TA to national funding s ources; * promoting airborne research in the academic community; * developing research activities in airborne instrumentation. Networking activities: - The ESF Scientific Advisory Committee (N1ESF-SAC), constituted of independent eminent scientists, super vises the activities of the EUFAR I3. - The Transnational Access Coordination (N2TAC) provides a unified management structure for all EUFAR TA activities. - Future of the Fleet (N3FF): aims at providing technical solutions for extending TA beyond EU suppor t, and elaborating on possible enhancements of the fleet. - Expert Working Groups (N4EWG) are supported for exchanging knowledge and promoting best practice and investments in airborne instrumentation. - Education & Training (N5ET): aims at promoting t he airborne research in the academic community. - E-Communication (N6EC): elaborates efficient solutions for the dissemination of the information and the evaluations of TA applications. Transnational Access Activities: Access is offered to 23 instrumente d aircraft, including scientific and engineering support for integration of instruments, planning of field campaigns, and data analysis. Joint Research Activities: The objective of the EUFAR JRA1 Airborne Aerosol Reference Pod" is to design and construc t an Aerosol
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Nanocomposite alumina ceramics for advanced technical applications' (NACATA).

assistant: **Concept**

- Alumina ceramics have an excellent wear cost index and are therefore used in many applications as wear parts and abrasive grits. However, these ceramics are fast becoming unacceptable where higher performance is needed such as in tooling for extrusion and tube drawing of metals. Higher performance materials such as ZTA, SiC and Sialons are now increasingly used in these situations despite the fact that the materials are too sophisticated for the application and thus the costs are too high. Therefore, there is a need to develop successful materials between the two extremes and a major impact will be achieved by enhancing the properties of alumina and, at the same time, maintaining reasonable manufacturing costs. Recent work on nanocomposite ceramics by the partners in this proposal clearly shows an improvement of 2 3 times in reduced wear rate for composites consisting of nanosize SiC particles dispersed in an alumina matrix, compared to monolithic alumina. This is believed to be associated with strengthening of the alumina grain boundaries so that fracture is essentially transcrystalline, rather than intercrystalline, which leads to an increase in the ratio of plastic deformation to brittle fracture near the surface of the ceramic. These encouraging results have greatly interested industrialists who would like to apply the benefits accrued in nanocomposite technology to technical ceramics and abrasive grits by substituting existing monolithic alumina materials with cost effective, higher performance nanocomposites. The objective of this project is to develop nanocomposites which can be fabricated by inexpensive processing (water dispersion, pressureless sintering) and to only use high pressure gas sintering for high performance parts. Building on a previous successful
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Deconvolving sources and sinks of carbon and sulfur in magmas to reconstruct DEGASsing from Large Igneous Provinces' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

The magnitude and consequences of future climate change depend on how Earth’s climate will respond to atmospheric chemistry alterations – vastly related to human activities. However, the complexity of the climate system makes future scenarios hard to predict. The geological record is our best source of information to constrain these scenarios by studying periods of Earth’s history during which volcanic degassing from outstanding magmatic episodes (Large Igneous Provinces, LIPs) acted as major forcing agents of climate and environmental change. Earth-system models that aim to reconstruct the global consequences of LIPs degassing proliferated in recent years, but they urgently need ground-truth gas emission data. The goal of DEGAS is to offer a new framework for obtaining these data by deconvolving sources and sinks of LIP magmatic volatiles, from the mantle source, across the crustal filter. DEGAS aims to: 1) quantify sulfur and carbon concentrations in LIPs parental magmas, hinging on the S-in-clinopyroxene method, pioneered by the PI; 2) investigate emblematic natural examples of magma-host rock interaction in volcanic basins from a within-sill perspective and with special focus on sulfur; 3) evaluate the role of the “crustal filter” as carbon and sulfur sink, with an unprecedented basin-scale approach. DEGAS investigates carbon and sulfur in LIPs magmas through multiple lenses, from the mineral to the basin-scale, in two natural laboratories, the Skagerrak-centered LIP (Oslo Rift), and the Karoo LIP. Knowing the initial volatile load and the modalities of magma-host-rock interaction is fundamental if we want to gauge the effect of the crustal filter and reconstruct source-sensitive parameters of degassing, such as isotopic signatures. DEGAS will constrain the magmatic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'ENabling sustainable COmbustion technologies using hybrid physics-based Data-driven modelING' (ENCODING).

assistant: **Innovation**

At the 26th UN Climate Change Conference of the Parties (COP26), the reached consensus points for the need of an energy revolution, in which hydrogen will play a key role, especially in Energy Intensive Industries (EIIs) for which electrification is more challenging. Still, current infrastructures are not ready to adopt hydrogen and other Renewable Synthetic Fuels (RSFs) in an efficient, safe, and sustainable way. ENCODING holds the promise to smooth the transition towards RSFs use, thereby helping decarbonise EIIs. To do so, ENCODING main objective is to train the next generation of digital combustion experts, by offering them an innovative training programme. The 10 doctoral candidates will gain multidisciplinary know-how in sustainable fuels, experimental techniques and numerical simulations of turbulent reacting flows, big data analytics and machine learning, and intersectoral experience (academic and industrial relevant training). Together, they will be able to create knowledge to develop a generalised hybrid ML-based digital infrastructure, with the capability to solve current and future outstanding questions to decarbonise EIIs.The unique training is only possible thanks to the participation of renowned academic institutions with partners specialized in combustion experiments and simulation (ULB, RWTH, CNRS, CNR), data analysis and dimensionality reduction (UPM, ULB), data-driven and ML-based modelling (ULB, RWTH, CNRS) and different companies in the whole chain of knowledge: sustainable fuels (Air Liquid), combustion systems (MITIS, NPT), fuel flexible burners (WS, TENOVA), pollutant remediation strategies (AGC, AMMR) and CFD software (CONVERGE, CFD Direct).


**Keywords:** Sensing, Data-driven modelling, Machine learning, Novel combustion technologies,Renewable
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Deep learning of chemical reactions' (DeepRxn) targeting Horizon Europe.

assistant: **Abstract**

The exploration of reactions is a central topic in chemistry. Compared to the success of machine learning for molecules, the modeling of reactions is lagging behind, especially for stereo- and regioselective reactions. Since current efforts toward  sustainable synthesis such as asymmetric organocatalysis or biocatalysis rely on the accurate prediction of enantio- and regioselective reaction pathways, new modeling approaches are needed. The proposed project aims toward developing new, data-driven deep learning frameworks for modeling organic and enzymatic reactions, focusing on chemo-, regio-, and stereoselectivity arising through intermolecular interactions with the reagent, solvent, or catalyst. In detail, we target the rule-free, stereochemistry-aware modeling and subsequent experimental validation of asymmetric organocatalysis to identify new enantioselective transformations, the exploration of new biocatalytic synthesis pathways including enzymatic cascades, and the accurate prediction of activation energies via developing new deep learning approaches. We will expand molecular graph-convolutional neural networks and graph transformers to reactions in a rule-free manner, and introduce hidden three-dimensional representations to account for stereochemistry and intermolecular interactions, yielding a versatile, open-source toolbox for reaction deep learning. This approach largely surpasses current approaches, which rely on two-dimensional representations, reaction rules, or three-dimensional input data, in offering the opportunity to model three-dimensional aspects and atom-mapping on-the-fly, for the first time, representing a significant breakthrough in this field. Its experimental validation campaign further allows for a direct application to the identification of n
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Neural network algorithm for ocean color (NAOC)' (NAOC), addressing dissemination and exploitation.

assistant: **Impact**

The aim of NAOC is to provide advanced algorithms for better exploiting the information contained in new multi spectral ocean colour satellite observations and to obtain a better estimation of bio-optical components of the ocean. Attention will be focused on atmospheric corrections and retrieval of marine constituents. We will use neural methodology, which are well suited to model highly non-linear phenomena and for inverting noisy empirical data sets. Validation will be done on already existing or concomitant in-site observations. NAOC innovation is to bring together scientists having a background in marine and atmospheric sciences and applied mathematicians. Scientists, managers, policy makers will benefit of NAOC. Thanks to the improvement of ocean colour data, they will be able to better assess the role of ocean productivity in the management of the planet Earth and to answer to the interrogation of people for the evolution of the ocean.