RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'High density integration by embedding chips for reduced size modules and electronic systems' (HERMES).

assistant: **Innovation**

The proposed HERMES project wants to initiate a new mainstream packaging concept not bound by the existing supply chain, and by large-scale manufacturing technology. The project is aiming at further developing the concept of embedded thin chips into electronic boards, as a base for an integrated manufacturing of electronic circuits.<br/>The project consortium will develop a technology for embedding active and passive components, allowing more functional integration and higher density. The technology will be based on printed circuit board manufacturing and assembly practice, and on standard available silicon dies, highlighting fine pitch interconnection, high power capability and high frequency compatibility.<br/>Apart from research necessary for the technological advances towards fine pitch, new materials, multilevel stacking, high reliability, essential developments are needed for setting up an integrated manufacturing. Key issues are testability of the circuits during and after manufacturing, yield and cost of the processes, and organizing the supply chain.<br/>The benefits of HERMES will be very large :<br/>\tTechnologically : Higher density because some borders" (the packaging/soldering interface) have disappeared, a smaller form factor and even possibility for 3D stacking\tLow cost : Large-scale production will be possible, with still high accuracy due to innovative equipment and processes (placement, LDI, etc.), and by using "cheap" PCB processes to a large extent. Even for a smaller number of modules to be made, the embedded component technology in a PCB manufacturing will be interesting, by the flexibility of PCB layout, and component placement.\tTime-to-market of complex and hybrid systems : By bringing the production and assembly of a module to one place, v
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Investigating Speech Processing in Realistic Environments' under Seventh Framework.

assistant: **Concept**

In everyday life, people listen to speech under a wide range of conditions that are “non-optimal” relative to the controlled conditions in laboratory experiments. Classical research methods can only deal with the effects of individual “adverse” conditions. This has contributed to the fragmentation of speech communication research in numerous sub-disciplines that have little interaction. While each type of adversity can have important consequences on its own, it is often the combination of conditions that conspire to create serious communication problems especially for elderly and hearing impaired persons.The long-term objective of Investigating Speech Processing in Realistic Environments (INSPIRE) is  creating a community of researchers who can exploit synergies between the sub-disciplines that investigate individual aspects of speech communication, resulting in a new curriculum: Real-world speech communication. We will develop novel research methods that take advantage of the massive amounts of experimental data that are becoming available and allow for the analysis of communication behaviours in real-world situations characterised by simultaneous presence of multiple “adverse” conditions. Computational models will be developed that allow to predict speech intelligibility for normal-hearing and hearing-impaired listeners under realistic conditions. INSPIRE will create a permanent collection of measurement data and tools that are accessible for external researchers for testing and comparing speech intelligibility models, thus enabling a breakthrough improvement in hearing instrument tuning.INSPIRE will achieve its objectives by bringing together E(S)Rs with leading academic scientists from the core disciplines in speech communication, R&D personnel from leading companie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Electrostatic Effects in Soft Matter and Biophysics'.

assistant: **Objectives**

Soft matter usually deals with research on materials that are not only mechanically soft, but, and more importantly, particularly prone to thermal fluctuation effects. Of particular interest are charged soft matter systems. They can be manufactured artificially like synthetic charged polymers (polyelectrolytes), which serve as superabsorbers in dypers, as flocculation and retention agents, as thickening and gelling agents, and as oil-recovery process aids. They appear however also abundant in all living organisms, since most of biologically relevant matter carries quite a large number of charges. Most of these materials perform important structural (e.g. membranes) and functional (e.g. DNA) tasks in the living matter that makes this interdisciplinary field particularly fascinating, moreover is should be of particular relevance for understanding the intricacies of the biological world. It can lead to such dramatic effects that thermal fluctuations and electrostatic interactions can revert the effective force between two equal charges in solution from repulsive to attractive.This is certainly not the only surprise in store in the world of the soft and the charged. The conformational behavior of DNA, the molecule" itself, appears to be governed to a large extend by this intricate interplay of electrostatics and Brownian motion. Since the analysis for electrostatic effects and thermal fluctuations combines such divers theoretical methods as continuum mechanics, statistical mechanics, field theory, molecular dynamics simulations and sophisticated laboratory techniques such as direct force measurements, laser tweezers, light, X-ray and neutron scattering, atomic force microscopy on the experimental side, this host of different methods is usually not present at any single univ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Improving policy and legislative mechanisms for international investment to renewable energy transition' in the context of a Horizon Europe call.

assistant: **Objectives**

Despite a global growth of investment in the renewable energy sector, there is clear evidence that lawmakers have been unable to present a comprehensive legislative mechanism to develop the sector, while policy makers have been unable to meaningfully provide institutional support. By 2022, according to Investment Dispute Navigator, investors have launched 145 cases against governments inside and beyond the EU with a total claim of about € 1018 billions to obtain compensation for the damages they had suffered because of weak legislative and institutional mechanisms. Such a situation has led to the postponement of 458 new renewable energy projects, increase of energy poverty by 1.4% and growth of carbon emissions by 2.7% around the globe. The iENERGY project aims to improve institutional and legislative mechanisms thereby assisting investors in identifying reliable investment destinations and supporting States in ensuring investment trends and avoiding risks of investment disputes in the renewable energy sector. The project will build an iENERGY Conceptual Framework on the basis of an interdisciplinary approach and will develop and analyse a Case Studies Container which will include data and information of cases concerning institutional and legislative mechanisms in the renewable energy sector. Finally, the project will create and implement an iENERGY Toolset by applying empirical mathematical programming methods to test various hypotheses of institutional and legislative contents taken from the Case Studies Container to identify legislative and institutional dispute resolution alternatives which meet the aims above.


**Keywords:** Green economy,  Energy governance,  Regulatory change,  Investment protection
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Fundamental breakthroughs in Lithium-Air Batteries', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Lithium-air batteries are a promising alternative to power the future electric vehicles. However, major improvements at the level of the fundamentals of the reactions will be required in order to improve their practical specific energy and rechargeability. Some of the challenges include: i) the instability of organic electrolytes in the presence of the superoxide radical formed as an intermediate in the reduction of oxygen, and ii) passivation of the electrode surface by the insoluble reaction products (lithium oxide and peroxide) leading to slow reaction kinetics. I plan to address these issues by means of a rational screening of soluble redox catalysts capable of decreasing the lifetime of the superoxide radical by rapidly transferring a second electron to the oxygen molecule. Such soluble redox catalysts will also act as shuttles, displacing the formation of insoluble reaction products from the electrode surface to the electrolyte, thus avoiding electrode passivation. The catalysts will be tested in selected electrolytes with good chemical stability. Redox active electrolytes will also be studied as they can potentially lead to very fast electron transfer reactions. Innovative approaches to avoid electrode passivation will be also investigated, including doping strategies to increase the conductivity of lithium oxides and peroxides and the application of ultrasound to erode the passivating layers on the electrode and enhance mass transport.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Elucidating the function of telomeric transcripts in the cytoplasm of ALT osteosarcoma cells' (CytoTERRA), addressing dissemination and exploitation.

assistant: **Impact**

The unlimited replication potential of cancer cells is enabled by their ability to renew their ends of chromosomes, telomeres. A minority of cancers utilizes a recombination pathway, named alternative lenghtening of telomeres (ALT), to maintain their telomeres. ALT cells exhibit increased DNA damage at telomeres and increased levels of TERRA, a lncRNA transcribed from telomeres. TERRA plays important roles in telomere biology, but it also has extranuclear functions. Short TERRA species were found in extracellular vesicles of lymphoblastoid and cancer cells, and they were found to stimulate inflammation. Notably, inflammation can have both anti-tumorigenic and pro-tumorigenic effects. Particularly, in osteosarcoma, a bone cancer with high ALT incidence, affecting predominantly children and adolescents, inflammation is connected to poor prognosis and metastasis development. Our preliminary results suggest that TERRA is present in the cytoplasm of human ALT osteosarcoma cells. We propose that the accumulation of cytoplasmic TERRA (cyTERRA) is induced by telomeric DNA damage, and that cyTERRA, similarly to extracellular TERRA, is capable of initiating an inflammation response. Since the cytoplasmic DNA sensor pathway is defective in these cells, we propose that TERRA plays a role of a DNA damage messenger that triggers the pro-tumorigenic inflammation. We will test our hypothesis by studying the characteristics of cyTERRA, elucidating the factors influencing its localization and studying the effect of cyTERRA depletion on inflammation signalling in these cells. The understanding of the function of cyTERRA in ALT osteosarcoma may introduce it as a marker for inflammation, and expose its export pathway as a therapeutic target. Since the variability of therapeutic outcome in o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Antibiotic persisters during infection: a tail of intestinal dominion' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Persisters are transiently non-growing bacteria cells that evade antibiotic treatment and immune response. Persisters have been associated with antibiotic treatment failure and the spread of antibiotic-resistance (AMR) through mobile genetic elements. Consequently, persisters contribute significantly to the morbidity and mortality of bacterial infections, and increased medical costs. Although it is known that many pathogenic bacteria are able to form persisters, the occurrence of persistence among commensal bacteria is yet unexplored. This project aims to identify and exploit commensal persisters able to antagonise and displace pathogenic persisters, offering opportunities for the development of innovative treatment options to arrest both the relapse of persistent infections and the horizontal transfer of AMR. To this effect, I will use a combination of cutting-edge omics-based tools, in vivo murine models and the well-established and relevant Salmonella enterica serovar Typhimurium enteric model pathogen. After identifying commensal species forming persisters (WP1), I will assess the ability of these persisters to compete with Salmonella persisters during infection (WP2) and to arrest in vivo horizontal gene transfer from Salmonella persisters to intestinal microbiota (WP3). My goal is to become a leading academic scientist in the intertwining fields of antibiotic-resistance and antibiotic-persistence, with emphasis on the involvement of persister cells in the maintenance and spread of mobile genetic elements encoding AMR. The state-of-the-art computational and experimental training at the pioneering groups of in vivo persister biology at Harvard Medical School (HMS) in USA and of genome spatial organization at the Institut Pasteur (IP) in France will be instrumental t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Intelligent Knowledge Platform for Personal Health Monitoring Services' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The eHealthMonitor project provides a platform that generates a Personal eHealth Knowledge Space (PeKS) as an aggregation of all knowledge sources (e.g., EHR and PHR) relevant for the provision of individualized personal eHealth services. This is realised by integrating service-oriented architecture, knowledge engineering, multiagent systems, and wearable/portable devices technologies. Innovations in eHealthMonitor are: (1) an adaptive, sustainable platform architecture for individualized personal electronic healthcare services; (2) reasoning, model evolution, and model summarization methods based on semantic models with different degrees of granularity, specificity, and different types of heterogeneity (syntactic, lexical, semantic); (3) distributed, adaptive knowledge sharing coordination methods which consider privacy protection requirements; and (4) personal eHealth services that support cooperation and decision making of the involved participants (patients, clinicians, social services): medical decision support services, personal information services, environmental and lifestyle risk factor monitoring services, and physiological and bio-chemical data monitoring services.<br/>The eHealthMonitor platform and health services are evaluated in three case studies: Deployment of the platform in two hospital scenarios built around two of the most relevant issues in the current EU eHealth environment – (1) dementia and (2) cardiovascular diseases – involving patients and medical professionals. (3) Deployment of the eHealthMonitor platform as part of prevention strategies where an insurance company provides its clients (patients and non-patients) access to the eHealthMonitor services in order to lower the risk of potential diseases.<br/>The impact is ensured through an activ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The role of carboxy-terminal phosphorylation sites in regulation of plectin's functions and interactions' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

Research objectives and content Plectin is a widely expressed protein of very large size that has all the attributes of a multifunctional crosslinking and organizing element of the cytoskeleton. It displays a multi-domain structure, versatile binding activities, and subcellular localizations that enable it to strengthen cells against mechanical stress forces. Biochemical studies have shown that plectin's interactions are differentially regulated by protein kinases, one of these being the cell-cycle control kinase p34cdc2 which phosphorylates plectin at a unique site during mitosis. During this phase plectin's ability to bind to vimentin in vitro decreases and it's solubility increases. Apart from this site, plectin's tail region contains a large number of potential phosphoacceptors, some of which occur in the recently found vimentin binding site. This project intends to investigate the role that phosphorylation in plectin's tail domain has on its interactions and functions, by studying interactions of bacterially expressed plectin mutant proteins (PMP's) and synthetic peptides in various phosphorylation states with intermediate filaments using binding assays, ultrastructural studies, and transfection studies. Training content (objective, benefit and expected impact) The proposed project will constitute a doctoral thesis project at the University of Vienna. The results of this project will contribute to the knowledge of plectin's functions and interactions, and its role in maintenance of cellular architecture. The aim is to report the results of this project to international journals, as well as writing a doctoral thesis on them. My expectation is that being involved in this project will not only greatly improve my experience with the methods and techniques mentioned, bu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Operational Management and Geo-decisional Prototype to track and trace agricultural production', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

This Specific support actions will complement the implementation of the 6th Framework Programme and may be used to help in preparations for future Community research and technological development policy activities including monitoring and assessment activities related to food safety and security. In particular, they will involve ferences, seminars, improvement studies and prototype implementation analyses involvement of working groups, expert groups as well as users group, operational support and dissemination, information and communication activities, or a combination of these, as appropriate in a SSA program. The aim of OTAG is to a sustainable, easily understood of track and trace emerging risks in beef production in the text of Southern e Countries and the EU policies. OTAG focuses on improving (i) innovative eomically viable mechanism, methods and geotechnologies, for recording reliable and accurate data on the origin and primary production of beef as well as the environmental ditions of the pasture territory and (ii) put in place an operational geodecisional system under trol ditions, to track and trace the mobility, provenance and state of beef cattle using emerging geospatial and geocommunication technologies. This SSA project take force on the European and Canadian knowledge, existing operational systems and precision geoinformatics tools as well as the interaction of experts and users group from Southern e Countries, Canada and EU. This SSA will take advantages of all the previous EU projects as well as the actual state of the art to demonstrate by a combination of operational prototype, dissemination, information and communication activities how we can efficiently support the management of emerging risks in beef production in the text of Southern e Countries