RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Dancing with giants: dynamics of dwarf satellite galaxies' in the context of a Horizon 2020 call.

assistant: **Objectives**

Giant galaxies like our own are surrounded by a large number of dwarf galaxy satellites that perform a complex orbital dance. Theoretical models predict that this dance should be composed of randomly oriented elliptical orbits, but Milky Way (MW) observations reveal the opposite: most satellites orbit in the same plane and have orbits that are more circular than expected. This discrepancy is a major problem that lacks an answer. It could signal a fundamental breakdown of the current cosmological model or, alternatively, that the MW is very atypical, a 1 in 1000 system. Studies of satellite orbits cannot yet be carried out for other galaxies, so the only option is to examine the MW in more detail. My proposed research will deliver ground-breaking new insights into the anomalous dynamics of satellites, and, through this, uncover the formation history of our galaxy. First, I will investigate the phenomena that give rise to the atypical orbits of the MW satellites. Two key drivers are the accretion of satellites along cosmic web filaments and the geometry of the dark matter halo of the central galaxy. Secondly, using state-of-the-art galaxy formation models, I will perform detailed simulations to predict the distribution of faint satellites and the stellar halo of our galaxy. These contain vital clues to the root cause of the anomalous satellite orbits problem. I will compare the model predictions to MW observations to make an unprecedented test of the current cosmological paradigm. The same simulations are essential to understand how representative are the MW satellites and stellar halo, and thus the extent to which they can be used to test the nature of dark matter and galaxy formation models.The proposed research combines my two areas of expertise, large scale structure
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'A disruptive pre-assembled Self-Regenerating solvent Recovery Plant based on the vapor recompression principle in order to diminish the emission of volatile organic compounds to environment.' to be submitted under Horizon 2020.

assistant: **Abstract**

The amount of volatile organic compounds (VOC) emission exceeds 15 MT/year in the world and 4 MT/year in Europe. These discharges constitute enormous environmental pollution and lead to serious health problems, such as respiratory insufficiency and asthma. Most of these emissions are caused by solvent-laden streams by companies in the packaging, chemical, degreasing and printing sectors.  Solvent Recovery is a well-known technology that, although it has been extensively used by big companies within Oil & Gas from 1980, it is neither cost-effective nor adapted to small projects due to its intrinsic nature, requiring a boiler and a cooling system.  As a consequence, thousands of tons of solvents, worth close to 1€/kg, are lost by SMEs within these markets and are discharged in polluted streams of air and water.  SITES here proposes Self-Regenerating Recovery Plant (SRRP), a new technology able to generate steam without boiler and reject heat without cooling system, achieving the same effect in a more compact cost-effective installation. It absolutely adapts the system to SME main requirements, solving the following issues:  • Cost: 85% reduction from 4.5 M€ to 0.65 M€  • Construction time: from 1 year to 2 days  • Footprint: only 24m x 4m against the previous 50mx50m  • Energy consumption: down to 1 kWh per kg of solvent instead of 2 kWh/kg  • Minimum capacity: as low as 5,000 Nm3/h vs previous 30,000 Nm3/h  • Safety: avoiding problematic operation by reducing regeneration temperature  • O&M: simplifying it by deletion of boiler and cooling tower  Additionally, global society shall be positively impacted because of the following points:  • Save of 6281 tonnes/year GHG emissions  • Avoidance of 4536 tons emission of VOC Solvents per installation  • Save of 24.500 kg/h of w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Multi-stakeholder, Cross-sectorial, Collaborative long term Research & Innovation Road Map to overcome Technological and Non-technological barriers towards more energy-efficient buildings & districts' (2007-2013) under Seventh Framework.

assistant: **Objectives**

The strategic objective of BUILDING UP project is to create an effective coordination of ETPs and major initiatives whose SRAs and activities address energy efficiency in the built environment from an NMP perspective, to identify and review the needs in terms of long term research and innovation. To achieve this, six ETPs, namely ECTP (European Construction Technology Platform), Suschem (Sustainable Chemicals), EUMAT (European Advanced Material Platform), Textile ETP (European Technology Platform for the Future of Textile and Clothing), ESTEP (European Steel Platform), FTP (Forest Technology Platform), including their national platforms, have joined forces with other relevant initiatives such as the ERANET ERACOBUILD in order to build a collaboration framework which, pioneered in this CSA under the NMP theme, will be an effective demonstrator to draw guidelines and policy recommendations for the engagement of the public and private sectors in the area of Energy Efficient buildings, preparing the ground for any future implementation beyond 2013 through relevant European and National public and private (industrial) research initiatives. Indeed the main differentiator of this Coordination Action versus the running EeB PPP is that we are targeting a much long term scenario well beyond 2013, outside the scope of the European Economic Recovery Plan.Addressing COMMON NEEDS AND CHALLENGES will pave the way towards the development of radically new products and services enabled by NMP technologies while ensuring that all the necessary bottlenecks and gaps at technological, non-technological and programme level are properly addressed for enhanced sustainability, competitiveness and employment, the key socio-economic challenges for a knowledge based and “eco-innovative” society in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Signalling in response to excess light in Arabidopsis' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

In excess light conditions, systemic acquired acclimation is induced in Arabidopsis plants, and H202 and Ca2+ are involved in that response. The aim of this project is to identify components of the cascade in response to excess light and relationships with wounding response.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Control mechanisms of nuclear receptor activity by coactivator proteins' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

Research objectives and content  Recent studies have led to the identification of a new set of proteins (called coactivators) that interact with the nuclear receptors in a ligand-dependent manner playing essential roles in mediating their transcriptional activities. Two of these proteins are SRC-1 (and related proteins) and p300/CBP family. Despite the growing information about these coactivators little is known about how they influence the transcriptional activity. We aim to elucidate the role of SRC-1 and p300/CBP protein families in the transcriptional regulation carried out by nuclear receptors. To do this we propose to: a) Produce SRC-1 and p300/CBP mutants and assay in vivo their abilities to modulate nuclear receptor activity, b) Introduce in intact cells the peptides responsible for the protein interactions testing how they affect the nuclear receptor transcriptional activity. Training content (objective, benefit and expected impact)  The completion of this proposal would help to define how ultimately nuclear receptors activate transcription and how these activities are regulated by their ligands, offering new insights into molecular controls of many process in which are involved the nuclear receptor superfamily. In addition many of these receptors and their ligands are associated with known human diseases and our results could have a potential impact in posterior trials looking for therapies for these diseases. Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Hygienic grey water container with reduced biofilm growth' (HYGIEIA).

assistant: **Concept**

The aim of the HYGIEIA project is to design a grey water container, and its manufacture procedure, with reduced biofilm growth, which is more effective, long lasting and economically competitive with respect to antimicrobial solutions currently implemented in the context of aircraft water sanitation; while at the same time searching for lighter weight but strong structural solutions. HYGIEIA is based on a plastic container with a wide range antimicrobial coating. The container will be designed looking for the perfect compromise between weight reduction over traditional designs, and giving a sufficiently rigid base for the coating technology while satisfying the requirements imposed by the standard RTCA Do160 Rev. G. The simplest, cheapest and most effective manufacturing process will be identified which is optimally adapted to the coating technology being applied from the point of view of initial surface roughness.


**Keywords:** antimicrobial coatings, micro-nano additives, surface functionalization, design, engineering
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Train pass-by noise source characterization and separation tools for cost-effective vehicle certification' (TRANSIT).

assistant: **Innovation**

TRANSIT aims at providing the railway community with a proven set of innovative tools and methodologies to reduce the environmental impact and improve interior acoustic comfort of railway vehicles. Noise is one of the main environmental challenges for the railway industry. Currently vehicle certification and authorisation requires extensive measurement campaigns on dedicated test tracks, leading to high cost and time expenses. In the future virtual certification of railway vehicles and improved authorisation procedures should reduce these expenses. Furthermore, increasing energy efficiency of railway transport is a key goal of Shift2Rail and efforts are ongoing to reduce vehicle weight, e.g. by applying composite material technology in the design of the carbody. However, this could potentially lead to increased interior noise levels as sound insulation is inherently related to mass, hence compromising the interior acoustic comfort.In this project the next major steps will be taken towards virtual testing, enhanced flexibility and compatibility in authorisation procedures. This will be achieved by developing accurate and robust source characterization and separation methods and techniques, and exterior noise simulation tools that will facilitate virtual testing and more cost-effective vehicle certification and authorisation methods. Regarding interior acoustic comfort, innovative material designs to increase sound transmission loss and absorption will be developed, leading to an improved interior sound quality within the weight constraints.The TRANSIT consortium has been carefully selected to bring together universities, research institutes and companies with proven expertise in railway noise and vibration and in other important fields such as microphone array technologi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Enabling Environmental Mycotechnologies' in the context of a Horizon Europe call.

assistant: **Objectives**

Enabling Environmental Mycotechnologies (EEM)EEM aims at developing soil fungal based remediation solutions to a commercial scale. Indeed, emerging fungal-based approaches have been proposed as attractive options for the biological treatment of polluted matrices, such as soil, sludge & sediments, and water. Such mycotechnological approaches also offer an exciting potential for the restoration of degraded ecosystems (mycoremediation and mycorestoration) as they have the potential to foster the adoption of low carbon, sustainable solutions in many industrial fields such as: agricultural biologicals (biostimulants, biopesticides, etc.), mycomaterials, production of enzymes for the industrial sector, products for the agri-food industry. The specific objectives of EEM are:•Securing NOVOBIOM’s core IP assets as one proprietary dynamic knowledge repository: this will be achieved by establishing a tailored fungal database for environmental applications•Setting NOVOBIOM’s strategic roadmap for the protection, diversification and scaling of all foreseen fungal applications.


**Keywords:** Bioremediation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Destination cilium: towards selective probing and perturbation of ciliary signaling' to be submitted under Horizon 2020.

assistant: **Abstract**

The primary cilium is a microtubule-based organelle that organizes a variety of cellular signaling pathways. Its importance for human health is illustrated by a large collection of cilium-based diseases, the ciliopathies, caused by mutations that alter cilium formation, structure, and function. Importantly, the mammalian Hedgehog signaling pathway is critically dependent on the primary cilium, dysregulation of which contributes to severe developmental defects and a variety of cancers. The ultimate goal of this work program is to enhance our understanding of the molecular mechanisms of ciliary signaling in health and disease. This is accomplished through the development of advanced technologies that provide a currently unattainable level of spatiotemporal control over ciliary proteins in mammalian cells. Unraveling the mechanisms by which the ciliary compartment orchestrates signal transduction is challenging, because ciliary and cytoplasmic roles of proteins involved in signal transduction are tightly connected, difficult to resolve and, importantly, context-specific. Here, an innovative chemical biology program is presented that provides a powerful toolbox to overcome these challenges, allowing the intraciliary manipulation, and therefore study, of ciliary proteins. Combining chemical probes, synthetic ciliary targeting approaches, and a modular enzymatic tagging strategy, this program provides unprecedented opportunities to probe, visualize, inhibit or degrade proteins at specific times and selectively within the ciliary compartment. Specifically, these tools will be used to decipher the relationships between tubulin acetylation state, intraflagellar transport, and Hedgehog signal transduction in wild-type and ciliopathy-mutant cells. These innovative work packages sy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Adenovirus-mediated muscle fibers engineering to overcome diabetes-associated deficient glucose disposal' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

A major cause of high circulating levels of glucose in non insulin-dependent diabetes mellitus (NIDDM) is the insulin resistance of skeletal muscle. Since muscle is the prime tissue for glucose disposal, the impairment of insulin-stimulated muscle glucose uptake is considered to lead to hyperglycaemia. The goal of the current proposal is to engineer muscle fibres to increase their capacity for glucose uptake and utilisation by the delivery of genes encoding for enzymes involved in the metabolism of glucose, namely glycogen phosphorylase and syntheses.Non insulin-dependent diabetes mellitus (NIDDM) is a disease characterised by the increase in the circulating levels of glucose in the blood. One of the major causes of hyperglycaemia is the inability of tissues to clear glucose from blood. Glucose clearance is in a large part insulin dependent since insulin stimulates the uptake of glucose in peripheral tissues (adipose and muscle). Due to its mass and energetic demand, skeletal muscle is one of the major sites for glucose consumption. However, glucose uptake by muscle can be promoted, independently of insulin, by exercise, hypoxia or epinephrine, which increase basal and insulin-stimulated glucose uptake, even in diabetic patients, through an undetermined mechanism. Also, the over expression of glycogen phosphorylase, by means of recombinant adenovirus-mediated gene transfer, in cultured human fibres leads to the acute stimulation of glucose uptake and consumption. The goal of this project is to use recombinant adenovirus technology to engineer muscle glucose metabolism by over expressing glycogen metabolising enzymes and to test the potential utility of genetic engineering for enhancing muscle glucose utilisation when insulin-stimulated glucose disposal is deficient. We
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Active and Passive Exploitation of Light at the Nanometre Scale'.

assistant: **Objectives**

Light and the various ways it interacts with matter is our primary means of sensing the world around us and it's no surprise that many technologies today are based on light. However, light cannot be imaged or focused to sizes below half its wavelength - known as the diffraction limit. To see smaller objects we must use shorter wavelengths. However, metals can shatter the diffraction limit of light and are now very promising for new technologies that expand the capabilities of computers and the internet and deliver new sensor technologies for healthcare, defense and security.We often take for granted just how strongly light interacts with metals. Electricity, oscillating at 50 Hz has a wavelength of thousands of kilometers, yet an electrical socket is no larger than a few centimeters; well below the diffraction limit! By structuring metal surfaces on the nanometre scale, this same phenomenon allows us to beat the diffraction limit in the visible spectrum. This approach has recently re-invigorated the study of optics at the nano-scale. I believe the paradigm of nano-optics is the capability to shrink light down to the length scales of molecular, solid state and atomic electronic states for the first time. With nano-optics, light-matter interactions are not only greatly strengthened but weak effects once difficult to detect are dramatically enhanced. If we can strengthen such weak effects we can use them to realize new capabilities in optics.Last year, I reported in Nature that metal-based lasers can generate light below the diffraction limit and sustain it by amplification thus overcoming the inherent resistance of metals. While conventional lasers transmit light over large distances, it is the light inside these metal lasers that is unique. I want to use this light for n