RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'pan-European Management of Biological toxin incidents through standaRdisAtion initiatives for Crisis response Enhancement' (EMBRACE).

assistant: **Innovation**

Biotoxins pose significant challenges to current crisis management approaches. Existing concepts of operation, derived from Chemical, Biological, Radiological and Nuclear doctrines, and Union Civil Protection Mechanism initiatives, do not address the distinctive and highly complex attributes of a biotoxin crisis. EMBRACE aims to improve Europe’s capacity to respond effectively to biotoxin incidents. We will consolidate and apply scientific and clinical knowledge of biotoxins to revise response protocols and deliver innovative solutions specifically tailored to address gaps and needs identified in current provision. Highlights include analysis of biotoxins not previously addressed in this context, risk-based recommendations for PPE and novel decontaminants, in vitro studies to identify human biomarkers of exposure, novel samplers, portable biosensors and field diagnostics devices, and software tools to assist responders in biothreat risk assessment. To ensure intersectoral and cross-border interoperability of these solutions and successful commercialisation of our exploitable assets, we will prioritise a carefully planned standardisation and valorisation programme. EMBRACE will engage with existing initiatives and projects to create a vibrant biotoxin knowledge network; a multi-sectoral community of stakeholders, on the basis of which a sustainable Biotoxin Task Force will be established as a source of expertise and guidance on biotoxin incidents both for EMBRACE and the wider community. The network of stakeholders and EMBRACE’s ambitious programme of scientific, technological, and operational advances will be supported by the creation of a biotoxin reference and stakeholder hub designed to facilitate knowledge exchange and provide users with direct access to widely dist
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'NEUral computing aRchitectures in Advanced Monolithic 3D-VLSI nano-technologies' (NeuRAM3).

assistant: **Concept**

We propose to fabricate a chip implementing a neuromorphic architecture that supports state-of-the-art machinelearning algorithms and spike-based learning mechanisms. With respect to its physical architecture this chip willfeature an ultra low power, scalable and highly configurable neural architecture that will deliver a gain of a factor 50xin power consumption on selected applications compared to conventional digital solutions; and fabricated in Fully-Depleted Silicon on Insulator (FDSOI) at 28nm design rules. In parallel the project will be validating the modules torealise RRAM synapses both planar and in a 3D monolithic structure.We will complete this vision and develop complementary technologies that will allow to address the full spectrumof applications from mobile/autonomous objects to high performance computing coprocessing, by realising (1) atechnology to implement on-chip learning, using native adaptive characteristics of electronic synaptic elements;and (2) a scalable platform to interconnect multiple neuromorphic processor chips to build large neural processingsystems.The neuromorphic computing system will be developed jointly with advanced neural algorithms and computationalarchitectures for online adaptation, learning, and high-throughput on-line signalprocessing, delivering1. an ultra-low power massively parallel non von Neumann computing platform with non-volatile nano-scale devicesthat support on-line learning mechanisms2. a programming toolbox of algorithms and data structures tailored to the specific constraints and opportunities of thephysical architecture;3. an array of fundamental application demonstrations instantiating the basic classes of signal processing tasks.The neural chip will validate the concept and be a first step to develop a European
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Bridge Reestablishment Solutions – Super Fast Telescopic Launching System (SF-TLS)' (SF-TLS).

assistant: **Innovation**

In our days, the effect of weather conditions, natural disasters, conflicts between peoples, refurbishment of degraded / weal structures requires daily bypasses to allow the freedom of movement of people. When a bridge collapse, the modular bridges available on the market are one of the conventional solutions that allow to restore the damaged infrastructures. In addition to the tragic human losses that these events often cause, there is always a high social and economic impact/cost due to the time between collapse and the bridge complete installation, that can reach several weeks or even months. BERD developed a new superfast launching system capable of launching an innovative modular bridge solution or even current modular bridges, based in a telescopic boom that can reduce the assembling and launching time up to 70%. Economic analysis shows that higher the importance of the road artery, higher is the payback of using the new Super Fast Telescopic Launching System (SF-TLS). Decision makers and roads and highways managers will have the opportunity to choose a fast reestablishment solution with a very important social and economic impact.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Sustainable Organic Coatings for Corrosion Protection' (SUSTICOAT) targeting Horizon 2020.

assistant: **Abstract**

BACKGROUND / NEED:There is a requirement to improve the sustainability of organic coatings by removal of materials hazardous to human health and by optimal use of raw materials and energy in manufacture and utilisation.AIM / OBJECTIVES:SUSTICOAT is a multidisciplinary project advancing understanding of how to improve the sustainability of organic coatings (paints) for corrosion protection to market applications. SUSTICOAT will make the connection between the scientific understanding and the production of real organic coatings, dealing with the complex issues that are involved in translating scientific concepts into new products. The objective of the project is to train 5 PhD students in both the innovation process required to go from scientific concept to commercial product and in a range of specific scientific skills: computational modelling, polymer synthesis, advanced characterisation, material science and chemical process engineering. TRAINING / RESEARCH:The training will be setup so that while each student will focus on a particular application area where they will be trained in the critical scientific skills they need, and with the other students they will have access through collaboration to a far wider range of expertise, such collaboration will be encouraged through the course of the project with specific training and opportunities to interact. SUSTICOAT by concentrating on realisation of scientific knowledge in real applications will give the students a unique set of skills in the translation of knowledge from academic to industrial use, this will be reinforced by appropriate academic and industrial training.IMPACT:SUSTICOAT combines the leading academic centre of corrosion science with the largest European manufacturer of corrosion protection coatings – provi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Enterprising Students Accreditation Platform for Europe' (2014-2020).

assistant: **Concept**

The Enterprising Students Accreditation (ESA) is a programme that has run for three years in the UK and has grown to now involve over 110,000 students annually. At present it is based on a simple online platform with limited functionality. Through the building of our European network we have identified a clear business opportunity to build a pan-European ESA network with programmes managed locally in each country. This project is centred on designing, testing and building a new ESSA Platform with increased functionality, capabilities and localisation. This will greatly increase revenue generation both centrally and for local partners, beneficially impact on youth unemployment, create a large student-specific network and positively contribute to our access to talent, profile and ultimately our position as a European seed finance venture fund. To achieve this we now need to apply focus to testing our model, validating the practical and financial feasibility and widening our EU awareness.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Implementation of widespread IC design skills in advanced deep submicron technologies at European Academia' in the context of a Seventh Framework call.

assistant: **Objectives**

The IDESA-2 project is a follow-up of FP7 IDESA-1 support action that addresses training of academic staff (professors, assistant professors and lecturers) from all interested European academia. The sole purpose of the IDESA-2 project is to continue making available didactic training material on the design flow for integrated circuits for advanced deep sub-micron technologies, free of intellectual property rights, for the benefit of European academia. Didactic material was developed and made available for reuse in the course portfolio of bachelor and master engineering curricula in IDESA-1. Training is organised in class-based hands-on sessions and advanced seminars using state-of-the-art multimedia technology over the web or on DVD.There currently is a road show of 4 different advanced implementation courses that tour different sites in Europe. These courses are hands-on courses using a train-the-trainer philosophy. All of these courses address the advanced implementation issues relating to the 90 nm process node. This brings the universities to a more advanced level of implementation skills to start engaging in 65- and 45-nm issues.The consortium has built a portfolio of public domain didactic seminars, addressing issues that are not addressed in the design flow courses but that start being of dominant importance for the 65 and 45 nm generation design flows. At the end of the IDESA-1 project (in May 2010), 35 didactic tutorials will be in the portfolio. The portfolio was established with the assistance of a Program Board consisting of representatives of the industry (both IDM and EDA) and of the Education and Training Working Group (ETWG) of ENIAC.IDESA-1 allowed to reach 16-25% of the target population (about 600 European universities, polytechnic schools and researc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Development of amplified fragment length polymorphism (ALFP) and its application to animal genome mapping and farm animal selection' (ALFP).

assistant: **Innovation**

The overall objective of the project is to demonstrate the utility of AFLP to animal breeding industries. An understanding of the underlying basis of variation at the gene level provides opportunities to increase the rate of genetic improvement achieved by selective breeding. Molecular biology is presently being rapidly adopted by plant improvement industries. Plant breeders have a number of advantages over their animal counterparts in terms of applying this new technology. Population structures and the large numbers of individuals within them provide excellent material for gene mapping and trait analysis. In addition, there are numerous sources of exotic germplasm that can be utilised to increase variation and to introduce new commercially valuable traits. Not surprisingly, animal breeding industries have been slower to exploit the potential of this technology. The development of genome maps for a number of animal species provides new tools of potential value for the improvement of farm animal selection. However, the information currently produced has not been applied due to the nature of the technology and the model structure of the populations used to produce these maps (e.g., divergent crosses using extreme populations such as wild boar). AFLP provides a technique with which to rapidly produce more cost effective markers and identify economically important genes directly in commercial breeding populations (the association between a marker and a trait may not be maintained between model and commercial populations. It offers the opportunity to develop a new set of solutions, which will be synergistic with the tools developed to date, to overcome existing technical hurdles and to establish a significant competitive advantage for European animal breeding industries. The
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Splice variants as modifiers of the Patched-Hedgehog signaling pathway' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

The Patched-Hedgehog signalling pathway is considered to be instrumental for normal developmental patterns but is also implicated in a number of cancer transformation processes that were recently found to include, basal cell carcinomas, but also pancreatic, digestive track and lung cancers. Studies, mainly in Drosophila, have allowed the dissection of the major components of this signal transduction system, that is the Hedgehog receptor Patched, the membrane signalling protein Smoothened, the intracellular transducers Fused, Suppressor of Fused and Costal 2 and the transcription factor Cubitus Interruptus.However careful analysis of this pathway in mammalian systems revealed a higher complexity than Drosophila, and this is exemplified by the duplication or triplication of some of these components. Humans, for example, have three Hedgehog ligands, two Patched receptors and three Cubitus Interruptus homologs. Moreover the process of alternative pre-mRNA splicing has revealed additional component comple xity. For example GLI1, a Cubitus Interruptus human homolog, was found to express three different mRNAs, each with a unique combination of 5- untranslated exons that confer distinct capacities in translational efficiency.The focus of this proposal is to expand on recent findings from our laboratory that suggest widespread splicing variation in components of this pathway. Specifically a Patched 1 variant that includes a novel first exon has been identified. Expression of this variant is up regulated by Hedgehog signalling and its functional properties are characterized by a pathway inhibitory capacity (Shimokawa et al, FEBS Lett. 578, 157-162, 2004). Additionally analysis of GLI1 expression revealed further complexity in the 5- exons, which is highly likely t o have function
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'OSAwards.EU' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

In its 30-month duration, OSAwards.eu will establish a European Public Recognition Scheme for Open Source (OS) Software (SW) and Hardware (HW). This system for European Awards will foster interest in contributions, and promote greater integration, utilisation and exploitation of OS SW and HW assets in Europe. It will do this by:•Celebrating Excellence: The European OS Awards, designed with guidance from an expert European OS Academy, will annually recognise outstanding contributions from individuals and projects throughout Europe.•Amplifying Impact: The strategically timed EU OS Week, coinciding with major European events like FOSDEM, will elevate the awards' profile and foster extensive community engagement.•Building European Expertise: The European OS Academy, composed of leading figures in OS, will work with the European Commission (EC) and OSAawards.eu to nominate and select awardees, ensuring the legitimacy and prestige of the awards while inspiring future generations. The Academy will also be built as an institution that implements and drives OSAwards.eu’s  Strategy for skills developmentOSAwards.eu brings a strong sustainability component into its approach. By leveraging existing communities and initiatives, we ensure the awards, week, and academy endure beyond the project's lifespan. This award system’s focus on public recognition and institution-building creates a lasting impact that serves as a world-renowned annual event highlighting Europe's OS achievements. By intertwining recognition (Awards), legitimacy and skills (Academy and Skills Strategy), and community engagement (Week), we cultivate a comprehensive strategy that celebrates excellence, fuels innovation, and guarantees the continued advancement of OS technologies in Europe, across society and industr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'New total synthesis of anthracycline antibiotics with anticancer activityand their conversion into non-toxic prodrugs'.

assistant: **Objectives**

Research objectives and content A total synthesis of the antitumor active prodrug F-826, which has been developed by Hoechst an two French research groups, has to be accomplished. This synthesis of anthracycline antibiotics follows the A+B--> ABCD approach which has not been used for the construction of the anthracycline skeleton. Task 1: The ring A and ring D building block of this synthesis have to be prepared. Task 2: These two building blocks have to be linked by a temporary Si-O-tether to afford an enediyne. A cobaltmediated cyclization of this enediyne should lead to the anthracycline framework which should be converted into Doxorubicinone. Task 3: Daunosamine e and its C-5 analogues shall be prepared starting from m-methoxybenzaldehyde. Task 4: Glycosidation of Doxorubicinone with Daunosamine and its analogues shall afford the corresponding doxorubicines representing the biologically active compounds. Task 5: The synthesis of the prodrug F-826 has to be completed by connecting Doxorubicine with protected 4-b-glucoronyl-3-nitrobenzylalco followed by deprotection. Training content (objective, benefit and expected impact) The applicant expects that the postdoctoral training allows her to continue the learning of techniques and topics of chemistry which could not be adquired at the home institution in Spain. After her academic training in Germany, the applicant plans to return to her former institution or to work in Spanish industry, to implement her newly acquired techniques. Links with industry / industrial relevance (22) This project is the result of a joint effort by researches at the University of Konstanz and the pharmaceutical research laboratories of Hoechst A G. The development of new selective methods and reagents is of great current interest in industrial
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'URBAN RECREATION: Energy efficient retrofit for carbon zero and socio-oriented urban environments' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Appropriate strategies to reduce energy consumption, increase Renewable Energy Sources (RES) penetration within local urban ecosystems seems to be the high priorities towards low carbon cities. In this context urban canyons (UCs) represent the core of the search for new intersections between energy issues and urban dwellers.The goal of the proposal is to demonstrate the techno-economical and social feasibility of zero energy-zero emission retrofit in existing UCs. To reach this aim the research will:- Develop a model which spatially depicts the energy of a selected urban area as a contribution to the mapping of the city energy consumption. The principles of the model -based on the city discretization into homogeneous districts characterised by several UC types- will be applicable to other districts and cities.- Study and evaluate the energy demand/potential of the UCs by designing –in different steps of actions- retrofitted scenarios to achieve carbon neutral UCs. The study will evaluate different solutions to diffusely integrate available technologies within UCs;- Promote further actions to fill the knowledge gap among low carbon techniques and their adoption at social and community city level.To investigate the validity of hypothesis, the overall aim is sub-divided into the objectives: 1) Urban discretized model; 2) Energy demand in the UCs; 3) Energy saving potential of UCs by passive and RES; 4) Zero Energy-Zero onsite emissions in the UCs, where additional energy savings production by synergies between passive and active systems will be addressed; 5) Overcoming existing constraints; 6) Outreach initiatives to apply retrofitting actions within real UCs.The study of energy potential of UCs will involve both stakeholders at public level and business economic actors/SM