RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Max Planck Junior Research Group for Novel Applications of Ultra-High-Q Optical Microcavities'.

assistant: **Concept**

Optical micro-cavities store in small volumes for extended amounts of time and find application in fundamental and applied studies, ranging from non-linear optics, quantum information to biological sensing and telecommunications. Recently, a rapid progress has been made in increasing the temporal confinement of photons in micro-cavities (as given by the quality factor, Q). These advances in Q-factor have allowed for the first time to observe the regime of strong coupling of an atom-cavity system, as well as al lowed the integration of non-linear optical oscillators, such as Raman lasers, optical parametric oscillators and optical switches on a silicon chip.The current research proposal will build on these advances and explore an hereto unstudied application area of ultra-high-Q toroid micro-cavities: Quantum Optics. Despite the tremendous promise of ultra-high-Q toroid micro-cavities, these devices have not yet been used for Quantum Optical experiments. Therefore, the proposed studies are both novel and timely and will to contribute to the field of secure quantum communication, a field that has mobilized the international physics community. Moreover, this proposal will explore combining chip based micro-cavities with the atom microchip technology developed in the host laboratory. The host laboratory is the Max Planck Institute for Quantum Optics (MPQ) in Garching, specifically the Division of Laser Spectroscopy of T.W. Haensch.The applicant is a German Scientist, who has completed his PhD and Postdoc at the California Institute of Technology (Caltech) in Pasadena, USA and who has recently been selected to establish a Max Planck Junior Research Group. The MPQ has arranged all necessary practical arrangements for a successful integration of the researcher. The present pro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Quantum-Native Communication Networks: from Quantum Message to Quantum Functioning' to be submitted under Horizon Europe.

assistant: **Abstract**

The Quantum Internet (QI) – a global network interconnecting remote quantum devices – is envisioned as the final stage of the quantum revolution, unlocking unprecedent communication functionalities. However, the key engineering challenge yet to be solved is the design of a protocol suite for the QI that can fully leverage the marvels of quantum mechanics. Current state-of-the-art proposals for the QI protocol suite adopt a layering model, mimicking TCP/IP standard-de-facto protocol stack of classical Internet. But this design choice limits the embrace of quantum features to the message delivered by the network, by leaving fundamental network functionalities to operate classically.Conversely, here, I PROPOSE a different and novel design, aiming at embracing the quantum marvels, not only in the message but also in key network functionalities, enabling so a quantum-native functioning for the QI. The VISION is that this design will unlock ground-breaking communication opportunities, as new forms of network resilience. QNattyNet overall GOAL is to design a protocol suite capturing the complexity of the quantum functioning by implementing a major paradigm-shift: from hierarchical protocol relationships to dynamic relationships. This goal will be pursued through 3 scientific objectives:- To design innovative protocols and functionalities for the QI by exploiting the quantum functioning.- To design a protocol suite for the QI able to capture the complexity of the quantum functioning.- To develop the QNattyNet simulator for supporting both the research community and the industry in the design and evaluation of quantum networks.This project is expected to have a deep impact towards deployment of the QI outside the laboratories into real world, by providing (through the designed p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Sexual Selection and Sleep in Arctic Shorebirds' (SSIAS) under Horizon 2020.

assistant: **Objectives**

What is the best way to attract and pursue a mate? This question is central for understanding how animal behaviour evolves through sexual selection. In the arctic, some male shorebirds almost entirely forgo sleep during the breeding season, and males that sleep least have the most offspring. These findings defy our understanding of the importance of sleep for optimal performance. So which specific behaviours are key to the success of these birds?Here, we propose using state-of-the-art accelerometers and machine learning models, together with conventional field methods, to explore how behaviour affects reproductive success in arctic shorebirds. Specifically, we will investigate whether the duration and frequency of courtship and territorial behaviours predicts number of offspring, and whether these behaviours vary with time spent awake. This unique research will focus on two species: polygynous pectoral sandpipers and sex-role-reversed red phalaropes. The research will combine the supervisor’s well-established methods for studying arctic shorebirds, the supervisor’s expertise in sexual selection, the researcher’s experience collecting and analysing large accelerometry datasets, and the researcher’s expertise in avian sleep.The proposed research will have four key implications. First, it will reveal whether overall time spent active is most important for reproductive success, as implied by previous research in pectoral sandpipers, or whether specific behaviours are key. Second, it will examine how extreme sleep loss relates to behaviour in wild birds, which might offer insights into sleep’s functions.  Third, it will elucidate the behavioural strategies of males and females in a novel sex-role-reversed mating system, and compare these with a polygynous species in the same
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Local Immunomodulation around implants by innovative auxiliary hydrogel-based systems encapsulating autologous and phenotype controlled macrophages', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

IMMODGEL aims to identify adverse immune reactions to dental and larynx titanium implants and to develop a novel therapeutic strategy to significantly decrease the implant and medical device failure caused by these reactions via design of an innovative immunomodulatory system. The system will be designed to be fixed to an implant via an adhesive polyelectrolyte multilayer and control the immune response by autologous, phenotype modulated macrophages encapsulated in a hydrogel. The auxiliary nature of the design allows it to be adjusted to any implant, medical device or transplant. IMMODGEL will apply complex systems immunology, epidemiology, and functional approaches to identify key adverse immune reactions caused by implants and detrimental macrophage phenotypes around titanium implants. This will be used to establish the optimal biomaterial composition and cytokine delivery system for the immunomodulatory hydrogel design to revert macrophage-induced inflammatory reactions  (M1) to the optimal tolerogenic and healing reactions (M2). Long-term fixation of the desired M2 phenotype will significantly decrease the level and duration of implant-induced inflammation, and optimise healing phase. The interaction of implants and medical devices with the immune system will be modelled to develop a “Foreign Body Response on-a-chip” to predict patient’s specific responses to implant materials and modify the immunomodulatory hydrogel accordingly, as a step towards personalized implants with minimal adverse reactions. The gels will be incorporated to engineered tissues for validation. Validation of the approach will be performed in vivo in animal models. Significantly suppressed inflammatory responses and optimal tissue remodelling and healing around titanium implants is expected. T
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Mechanisms of The Timing of CAB expression 1 (TOC1) regulation and role of casein kinase 2 (CK2) in the Arabidopsis circadian clock' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Many biological processes in nature exhibit a cyclic pattern of activity with a period that roughly matches that of the earths rotation. These 24-hour rhythms are regulated by an endogenous timing mechanism, the circadian clock that enables organisms to anticipate rhythmic changes in the environment and to accordingly synchronize their physiological state. In plants, the circadian clock controls the diurnal amplitude and phasing of a wide variety of rhythmic phenomena. The precise regulation of TOC1 (Timing of CAB expression 1) mRNA and protein expression has been shown to be crucial for the functioning of the clock. The research proposal is focused on the identification of mechanisms that regulate TOC1 function. Yeast two-hybrid studies have shown the interaction of TOC1 with the casein kinase 2 (CK2). We will examine the possible role of CK2 in TOC1 phosphorylation, stability and subcellular localization and their implications in the Arabidopsis circadian system. In a long term, these studies will help us to better understand the mechanisms of clock function as well as the regulation of important biological processes in the plant such as the photoperiodic regulation of physiology and metabolism. These goals will be achieved through different specific objectives. The project will be initiated with the in vivo characterization of the CK2 and TOC1 interaction. These studies will be performed by co-inmunoprecipitation assays in plants and by the development of new methodologies that will allow the in vivo sub-cellular visualization of theTOC1-CK2 interaction. We will identify the TOC1 phosphorylation sites by biochemical approaches and perform studies of the possible role of CK2 in the phosphorylation state of TOC1 and in the control of TOC1 protein stability. The pervasi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Political Economies of Refugee Camps' (2021-2027).

assistant: **Concept**

The camPEconomies project explores a crucial aspect of the campization of the refugee accomodation in Europe that has not yet been addressed in literature: the multiple and intertwined economic relations that develop in and around refugee camps. The research will be conducted through a combination of qualitative and quantitative methodologies drawing from an interdisciplinary approach - my postgraduate studies on Economic and Urban Development, my Phd on social and cultural geography, and my long lasting research interest around migration and gender. An in depth fieldwork research will be take place in two refugee camps in the Balkan Route, the camp of Shisto in Greece and of Obrenovac in Serbia. The aim is to analyze economic and social relations in multiple and interlocking socio spatial scales: from (a) the funding of the camps by institutional actors, to (b) the socioeconomic relations connecting the camp to surrounding areas and to (c) the grassroots economic practices of refugees. Apart from disseminating this original research within academic community (publications, conferences, an educational toolkit) the project aims to intervene in the level of policy making (Policy Report, open online event). Still, following the principles of Open Science and as the discussion around refugee camps is also a public discussion the project will develop an innovative strategy to communicate both the research process (research blog, podcasts) and the results (interactive maps, public discussions) to wider audiences.  The supervisor, Prof. Dr. Manuela Bojadžijev, is a professor in the Institute of European Ethnology and a founding member of the Berlin Institute for Empirical Integration and Migration Research (BIM) both based in Humboldt University in Berlin where the project wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Equilibrium properties and kinetics of self-assembly of anisotropic colloids and molecular liquids' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The proposed research project aims to studyself-assembly  of new materials made of anisotropic colloids as building blocks and to unravel the mechanism of crystallization in molecular liquids, such as water.The last few decades have seen a huge growth in the research on novel soft materials to be exploited in nanotechnology, and an efficient route to build them is to make use of self-assembly. The term self-assembly refers to the reversible and cooperative assembly of predefined components into an ordered super- structure. Self-assembly is responsible for nanostructure formation in colloidal, amphiphilic, polymeric, and biomolecular materials.However, unlike most of the work of the last decade on particle self-assembly, which has focused on colloidal systems of spherically-shaped particles with isotropic interactions,not enough  effort has been put yet into understanding and controlling the self-assembly mechanism in suspensions of irregularly shaped or/and anisotropically interacting colloidal particles (the latter also called ""patchy colloids"").Patchy colloids have been recently used to reproduce the colloidal analogue of a vitally important molecule: water.Water is the  only known non-metallic substance that expands when freezing.Understanding the mechanism of water crystallisation (or ice formation) isof fundamental interest to many scientific disciplines, ranging from meteorology to food science and biology.However, on the one side length and time scale relevant for water crystallisation are unattainable with up-to-date experimental techniques.On the other side, computer simulations of ice crystallisation have been a great challenge, the difficulty been that hydrogen bonding between individual water molecules yields a disordered three-dimensional hydrogen-bond ne
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Mapping the Uncharted Human Metabolism for Novel Food Bioactives' (BioTransform), addressing dissemination and exploitation.

assistant: **Impact**

BioTransform is a multidisciplinary doctoral network aiming to investigate the role of certain constituents found in food products (food bioactives - FB) on human health, focusing on their metabolism. FB coexist with nutrients, but they are biologically active compounds present in our diet and characterised by great structural variability and biological properties. Despite the imperative role of gut microbiota in health maintenance and disease prevention, the available information regarding FB metabolism remains scarce and the biotransformation occurring in the human organism highly unexplored. Thus, the goal of BioTransform is to combine state-of-the-art methods, technologies and approaches in a complementary and integrated way to reveal the impact of FB and their metabolites (biotransformation products) on health and disease. To this end, human pilot studies, in vitro and in silico metabolism simulation methods, gut microbiota sequencing, metabolite profiling and metabolomics will be employed. Metabolites will be biologically profiled through biochemical and cell-based assays. In BioTransform, the metabolism of olive and bilberry FB (secoiridoids, phenols and polyphenols), which are European flagship food products with proven activity in metabolism-related pathologies, will be systematically investigated. A key innovative characteristic of BioTransform is the holistic approach towards metabolism of FB, unique so far, combining all required disciplines and including experts at EU level. BioTransform objectives will be accomplished through eleven complementary doctoral projects from nine education and research entities, additionally including the participation of six associated partners from the private sector and one from academia. Beyond the scientific achievements, t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Beyond genotype to phenotype: how ancestor lifestyle impacts on lifespan variation in descendants'.

assistant: **Concept**

There are many examples in nature where inter-individual variability in life-history traits is exploited as an adaptive strategy. I and others have shown that inter-individual variability in the longevity pathways –and in particular, in stress response genes- has consequences for genetic/environmental phenotypic robustness as well as for lifespan in Caenorhabditis elegans. My main interest is to uncover the causes that explain inter-individual variability in lifespan. The variability across individuals must include an important non-genetic component because the laboratory strains of this nematode are genetically homogeneous. I propose that lifespan variation is a by-product of non-genetic sources of variability in the pathways that control longevity. Strikingly, inter-individual differences in stress responses are transgenerationally transmitted. Transgenerational memory is an adaptive strategy that informs the next generation about the likely environmental cues that will be encountered, and sets patterns of gene expression by the incomplete erasure of chromatin marks in the germline. I hypothesise that transgenerational epigenome inheritance introduces transcriptional variability for genes that influence lifespan. Also, I propose that the probabilistic nature of lifespan is caused by inter-individual differences in the inheritance of longevity genes that set the rate of ageing from early development. Understanding the basis of lifespan variability is crucial for personalised medicine, where not the average population but rather the individual is centre stage. It is equally crucial for the identification of new factors that may have been missed by the analysis of population averages that can have an impact for human ageing and health. More generally, I propose the inter
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Novel application targets and products derived from wild arctic berries' (WILDBERRY).

assistant: **Concept**

Novel application targets and products derived from wild arctic berries (WILDBERRY)The demand for nutraceuticals and functional foods is on the rise due to increased consumer interest in convenient, safe and healthy foods. One of the solutions to meet this demand are wild arctic berries, many of which contain significant amounts of anthocyanins. Anthocyanins act as antioxidants and are known for their beneficial effect to cardiovascular health, vision and prevention of diabetes, among other benefits. We (Extrx Oy) are a company established in 2016 with aim to produce high quality anthocyanin extract, alongside with other novel products, from local berries. We are located in Sotkamo, Finland, in the area where anthocyanin concentrations of bilberries have been scientifically shown to be highest in the world. With the significant resources of wild berries available, our focus on high quality and our contacts abroad give us a good chance to be successful and in the forefront of the industry in the future. Project focus will be on adsorption chromatography process and product development as a part of the company's R&D team. Although the process itself is straightforward, there are still areas where novel ideas are needed to enhance the cost-efficiency of the process and economical potential of the products. These are 1) potential uses for the solid berry fraction,2) potential uses for the sugar fraction and 3) anthocyanin extraction process optimization. For the applicant we are offering the opportunity to further their skills and conduct interesting research while working at a company with great ideas and prospects for the future. The aim is to use the findings of the project to improve the process and to deliver new products to global market, as well as to either patent o