RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'PATHOLYTIX: Using Artificial Intelligence to Transform Clinical Diagnostic Pathology'.

assistant: **Innovation**

Routine diagnosis on biopsies and tissues is performed by expert pathologists. However, the pathology sector faces a major crises, due to soaring numbers of biopsies for diagnosis, coupled with decreasing numbers of trained pathologists, which is affecting patients. Technology can alleviate this crises by using computer aided diagnosis (CAD) to increase productivity, reduce costs and streamline workflow.Deciphex Ltd is an Irish company developing an innovative Computer Aided Diagnosis (CAD) system which will revolutionize the medical diagnosis pathology sector. Our ‘PATHOLYTIX’ system uses state-of-the-art artificial intelligence techniques to automate the laborious and costly pathology assessment (currently done via microscope). By transforming this centuries old clinical practice, we aim to become a market leader in new CAD industry. We currently have prototype technology and preliminary data, to identify different tissue and cell types. In this feasibility study we will perform pilot studies in a US based clinical pathologist, to demonstrate our tool can identify various diseases. In Phase 2 of the SME Instrument, we will undergo additional development, extensive validation, and build the data management framework and user interface.    There is a large global target market for PATHOLYTIX, which is growing each year driven by an increasing population and higher prevalence of diseases (such as cancer). Hence hospitals and clinics worldwide process hundreds of millions of biopsies per year. With regards to competitors, there is no direct competition. Competitors offer individual components of the pathological workflow, not fit-for-purpose solution like PATHOLYTIX.  Overall, PATHOLYTIX would have a big impact on the pathology sector, by increasing productivity and reduc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Single cell RNA-seq analysis of individual sperm cells to identify transcriptomic differences potentially involved in preferential fertilization.' (SAMEorNOT) targeting Horizon Europe.

assistant: **Abstract**

Human societies are sustained by flowering plants in different ways but especially as a key food supplier. However, it is known that increasing global temperatures strongly affect plant reproduction and the growing human population will require more food in short-middle term. Thus, to create new crop varieties more resistant to heat stress and with enhanced yield, a deeper understanding of the mechanism of plant sexual reproduction will be crucial for increasing the efficiency of plant breeding programs. Plant reproduction relies on a double fertilization process, in which two sperm cells from a pollen grain reach the ovule and one fertilize the egg cell while the other the central cell. In some species with dimorphic sperm cells a preferential fertilization of each sperm cell has been described, but for Arabidopsis thaliana as well as for many economically important crops with isomorphic sperm cells this question remains unclear. The main goal of this project is to identify by single cell RNA-seq analysis potential transcriptomic differences between the two Arabidopsis sperm cells. To do that, individual sperm cells from pollen tubes growing through female stylar transmitting tissue (semi in vivo) will be isolated by micromanipulation using a specially designed microfluidic chamber on an inverted microscope. The identification of differentially expressed genes would enable for the first time the creation of a sperm single-cell marker line to eventually explore a hypothetical preferential fertilization in Arabidopsis. These results can be adapted for plant breeding programs to develop impactful biotechnological tools, like haploid inducer lines with genetically modified sperm cells to specifically deliver components in the egg cell to induce in vivo gynogenesis. Additio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Htr safety approach and licensing main issues'.

assistant: **Innovation**

The Modular High Temperature Reactor (HTR) uses simplicity instead of economy-of-scale to attain economic viability, meaning elimination of safety relevant components incorporated in current nuclear plants, because of recognised inherent safety features.A common European safety approach for this reactor type will therefore be established and the feasibility of the licensing of such reactors will be evaluated.Key safety issues and accidental conditions, like fission product transport, air ingress and local core heat up, for this reactor type will be researched and classified. The confinement requirements, the equipment classification rules, and the parameters will be monitored and controlled will be established.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'COMMERCIALIZING THE FIRST HEAD-UP-DISPLAY FOR  OFF-HIGHWAY VEHICLES', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

An overload of information in conventional instruments in commercial vehicles affect driver, vehicle and public safety. HUD Solutions, Sweden AB developed a Head-Up Display (HUD) technology to display the most important information within the driver’s line of sight. With HUDs, the image is perceived to be hovering in the air a few meters in front of the vehicle and driver can see the essential information without looking down. By enabling better human-machine interaction, safety and productivity are increased which, in turn, leads to reduced costs.HUD Solutions Sweden AB validated a prototype of a HUD for OHVs in a partnership with leading, world-class OEMs in 2017 during an extensive research project financed by Vinnova, Sweden’s innovation agency. The company obtained a clear proof of concept and is now ready to develop a clear industrialization plan for the HUD technology for Off-Highway Vehicles (OHVs).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'A REVOLUTIONARY PORTABLE AND ENVIROMENTALLY SOLUTION FOR CHEWING GUM REMOVAL USING STEAM ON DEMAND TECHNOLOGY' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Chewing gum seems like a fairly innocuous substance until you step on it or sit on, or until you are faced with removing it from footpaths and public places. Nowadays, chewing gum removal has become a worldwide cleaning concern and a huge problem for local authorities, commercial property owners and property management companies who are responsible for the cleanliness. Spirit Circuits Ltd has invested significant development time over last two years to come up with a safe, economical, and green solution to the problem of removing chewing gum which has resulted in an environmentally friendly cleaning equipment (EcoGUM).Established in 2003, Sprit Circuits Ltd (SCL) is one of the UK’s most innovative Printed Circuit Board (PCB) manufacturers. Since our company was founded, we have invested in development, producing a range of patented technology and we have ensured that innovation plays a key role in everything from proactively researching new materials and technologies to executing a business strategy – thus, consolidating our position in the electrical and electronic market.With the exploitation of our proposed system, we expect to create 12 new jobs and enter a new market. Moreover, the successful implementation also significantly enhances the profitability of SCL. It would return an expected turnover of nearly €14mill until 2020. Phase 1 project aims at assessing the activities needed to standardize the product, scale up to a large pilot implementation and test the market to achieve a sound business model. In Phase 2 we expect to perform a pilot study to improve the final quality of the EcoGUM, offering the best value machine in the world and the first fully Lithium battery powered Steam Cleaning Machine prototype based on steam on demand technology, that integrates al
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Ecological, biological, silvicultural and economical management for optimisation of chestnut wood and alimentary production within a sustainable development frame' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

The chestnut stands (Castaneda saliva Mill.), situated on the foothills of Europe, between forests and agricultural land, are important, both from the scenic and environmental point of view, and for the local economy and culture These agro ecosystems are threatened by the activity of man, by global change, by fungal diseases and by the poor possibility, at the local level, of the commercialisation of their products. The project comes from a multidisciplinary scientific experience in biology, genetic improvement, ecology, ecophysiology, pathology and economy, with the aim of giving valid scientific solutions for the optimisation of the management and a correct use of similar ecosystems, for a real sustainable development. The project is set in the EU policy of the Fifth Framework Program 1.1.1, Key Action 5.3, Thematic Priorities: 1.1.1.5.3, 1.1.1.5.3.1. 1.1.1.5.3.2.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Integrated drug discovery approach to generate brain-penetrant inhibitors of glioblastoma cell proliferation', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Glioblastoma multiforme (GBM) is the most common and aggressive cancer that begins within the brain. Without treatment the average survival following diagnosis is merely 3 months. Although clinically-approved kinase inhibitors present promising features to treat GBM, most of them do not cross the blood brain barrier (BBB), impeding their clinical use in GBM patients. We propose an agile approach that combines ligand-based drug design of highly-focused compound libraries and first-in-class phenotypic assay for simultaneous screening of BBB penetration, unspecific toxicity and anticancer properties, in an iterative manner. This approach will allow a one-step selection of hit / lead compounds from in-house generated compound libraries that cross the BBB to accelerate the design of CNS-active anticancer drugs. Furthermore, the use of chemical proteomics and the state-of-the-art proteomics techniques will facilitate the identification of the kinases and / or pathways that are involved in the observed phenotype, which could result in the discovery of novel GBM oncotargets and unknown modes of action. This highly innovative integrated approach has the potential to speed up preclinical drug discovery efforts in CNS diseases, and in doing so, promote European Scientific Excellence. As a developer and provider of such tools, the applicant will be positioned in a privileged position for starting cross-disciplinary collaborations with academics and Pharma across Europe and for establishing herself as an independent researcher.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Structural studies of Inositol poly-Phosphate Kinases' to be submitted under Sixth Framework.

assistant: **Abstract**

A multiplicity of inositol phosphates exists in biology, with functions in many diverse aspects of cell biology, such as ion channel physiology, membrane dynamics and nuclear signalling. This diversity involves a whole array of proteins that either metabolize inositol phosphates or mediate their intracellular functions.Recently, a family of inositol phosphate kinases was identified whose members are conserved from yeast to humans. The main focus of the presented project is to study the inositol phosphate kinases, which are involved in the metabolism of the inositol pyrophosphates. Inositol pyrophosphates were recently shown to be a source of the high-energy phosphate for phosphorylation of certain proteins, similarly to ATP.By solving the three dimensional structures of the recombinant inositol poly-phosphate kinases which make the inositol pyrophosphates, we would like to get a better insight into the metabolism of the inositol pyrophosphates and their biological roles. Besides X-ray crystallography as the main tool, other structural biology and biochemical techniques will be used to uncover still so many unknowns in this field of research.The expected results are believed to represent a great contribution to the knowledge about the biologically very relevant molecules, inositol phosphates. Additionally, the opportunity for the applicant to professionally reintegrate in country of the nationality is also believed to be of a mutual benefit, for the scientist herself, her scientific career, and for the quality of the European research.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Middleware for collaborative Applications and Global vIrtual Communities' (MAGIC).

assistant: **Innovation**

The MAGIC Project seeks to establish a set of agreements for Europe, Latin America and other participating World Regions, aiming at consolidating and completing the building blocks of middleware necessary for the establishment of a marketplace of services and real-time applications for international and inter-continental research groups which facilitates mobility and the work of global science communities. More specifically, the project specific goals are:-To foster the deployment of the platforms that enable mobility of people and seamless access to services by promoting the establishment of identity federations interconnected via eduGAIN, creating awareness of privacy and security issues and spreading eduroam by: sharing experiences, carrying out training and making available shared infrastructure to ease the process in the partner world regions.-To develop a model for inter-operation between NREN cloud application markets of participating world regions, based on cloud provisioning and taking advantage of applications developed and run by NRENs across different continents to create a model for a worldwide application market for collaboration tools and services-To seek consensus among participating world regions on the importance of interoperability of real-time applications and work towards the adoption of standards such as those proposed by the Global CEO Forum to promote the creation of a worldwide environment for these applications. -To foster the collaborative work of Global Science Communities by actively promoting the participation of Latin American and other regions’ researchers in European Commission Calls and those of other international funding agencies with high impact in the participating regions and other networking activities.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Economical production of sige material for microelectronics and optoelectronics applications' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The project will develop an economical, reliable 200/300 mm industrial tool for fabrication of SiGe pseudosubstrates by growing relaxed layers of SiGe on silicon wafers. The project will demonstrate that SiGe-PS can be used for the fabrication of high performant devices for Microelectronics and Optoelectronics (MOSFET's, Electroluminescent diode and Solar cell). These demonstrations: i) open the road to overcome severe bottleneck CMOS technology will face in the next 10/15 years ii) open the road to monolithic integration of GaAs with bulk silicon and fabrication of integrated EL diode for System on Chip applications iii) allow fabrication of cheap large area solar cells. The Consortium gathers together prestigious European laboratories in the fields of SiGe, dep sumicron CMOS technologies, optoelectronics. Project achievements will increase competitiveness of European Technology.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Waste Heat to Energy' (WH2E) under Horizon Europe.

assistant: **Objectives**

To cope with the growing global energy consumption and sustainable development scenarios, Waste Heat Recovery is an efficient, green and economic solution to help highly demanding industries save valuable energy.However, while low grade waste heat (<100) constitutes the largest source of heat with an annual 3700Mtoe, corresponding to 63% of the total recoverable heat, it has not been widely exploited yet due to technical and economical difficulties. Only valorisation of high and medium grade in the form of electricity is largely deployed at industrial scale.In the WH2E project, Sweetch Energy is proposing an innovative way to convert low grade waste heat into electric power. To do so, two major steps will be necessary: the conversion of temperature gradient into salinity gradient using thermo-sensible ionic liquids, coupled with an osmotic engine (INOD) to generate electric power as final output. The INOD (Ionic Nano Osmotic Diffusion) technology, developped by Sweetch Energy, is based on the most advanced nanotechnologies and specific membrane design.At the end of the project, a testing phase in partnership with an international industrial corporation will allow to reach a TRL6 and secure the market readiness. Sweetch Energy is targeting first the industrial sector and ambitions to become a global leader in the decarbonized electricity sector. The project is supported by Veolia and Solvay.


**Keywords:** Osmotic energy,  Low grade waste heat,  Salinity gradients,  Renewable energy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Advanced biohybrid lighting and photovoltaic devices' to be submitted under Horizon 2020.

assistant: **Abstract**

InOutBioLight aims to design multifunctional rubbers with enhanced mechanical, thermal, color-converting, and light-guiding features towards advanced biohybrid lighting and photovoltaic technologies. The latter are placed at the forefront of the EU efforts for low-cost production and efficient consumption of electricity, a critical issue for a sustainable development.In this context, the use of biomolecules as functional components in lighting and photovoltaic devices is still a challenge, as they quickly denature under storage and device operation conditions. This paradigm has changed using an innovative rubber-like material, in which the biofunctionality is long preserved. As a proof-of-concept, color down-converting rubbers based on fluorescent proteins were used to design the first biohybrid white light-emitting diode (bio-HWLED). To develop a new generation of biohybrid devices, InOutBioLight will address the following critical issues, namely i) the nature of the protein-matrix stabilization, ii) how to enhance the thermal/mechanical features, iii) how to design multifunctional rubbers, iv) how to mimic natural patterns for light-guiding, and v) how to expand the technological use of the rubber approach.To achieve these goals, InOutBioLight involves comprehensive spectroscopic, microscopic, and mechanical studies to investigate the protein-matrix interaction using new polymer matrices, additives, and protein-based nanoparticles. In addition, the mechanical, thermal, and light-coupling features will be enhanced using structural biocompounds and reproducing biomorphic patterns. As such, InOutBioLight offers three major advances: i) a thorough scientific basis for the rubber approach, ii) a significant thrust of the emerging bio-HWLEDs, and iii) innovative breakthroug