RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Effects of individual heterogeneity on stochastic population processes: the case of nonbreeders' to be submitted under Seventh Framework.

assistant: **Abstract**

Successful population management depends on our ability to predict future patterns of population abundance and extinction. This requires a clear understanding of the mechanisms underlying population dynamics. In this project I will integrate mathematical, statistical and ecological approaches to provide new understanding of effects of individual heterogeneity on the stochastic dynamics and genetics of populations.I will achieve these objectives by developing and analyzing new stochastic population models that incorporate both random and nonrandom differences among individuals, specifically focusing on the role of nonbreeders in driving population processes. I will then use two long-term datasets on wild bird populations (Green-rumped parrotlets and European shags) to parameterize these models and quantify the impact of nonbreeders on key population processes and extinction risk. Nonbreeders are often present in wild populations, but are routinely ignored when predicting population dynamics, potentially introducing errors into management recommendations. In this project, I will therefore provide new theoretical and empirical advances and quantify their potential impact on management decisions.I will spend two outgoing years at the University of California, Berkeley, working with world-leading scientists in avian population ecology, statistical ecology and theoretical demography to learn and develop new methods of stochastic modeling and ecological data analysis. By combining these new skills with my existing expertise in mathematical biology, I will build an unusual skill set that is currently in high demand. I will bring this expertise back to a leading European research university, the University of Aberdeen, where my ability to link the disciplines of ecology and math
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Applications of New Chiral Nitrogen based ligands in Asymmetric Catalysis' under Seventh Framework.

assistant: **Concept**

Catalytic asymmetric chemical processes (synthesis) that create new C-C, C-O, or C-N bonds from simpler molecules are also hugely important as this is how chemical complexity is built up. The scientific community, and specially the industry, is interested in the development of cheap, bench stables and highly selective catalysts for non solved or new developed catalytic asymmetric reactions. We proposed a new family of N-based ligands, and new reactions where they can be applied, as alternative to the use of the P-based. Based in the excellent precedents (asymmetric Diels-Alder and Suzuki-Miyaura reactions) using hydrazone-based ligands, I believe the proposed hydrazone-based ligand will provide a new and interesting family of chiral ligands for a wide number of asymmetric metal catalysed reactions. We will then apply the new chemistry in the synthesis of biologically important molecules.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'DEMONSTRATION PLANT FOR ADVANCED MILL CONCEPT' in the context of a Fourth Framework call.

assistant: **Objectives**

The main aim of this project is to achieve up to 50% energy reduction per produced ton cement, in comparison with the existing ball-mills. Noise level will be reduced to 85dB from the existing 120 dB, maintenance costs are expected to be reduced with 20%.The main energy saving will be achieved in the mill itself by:The use of air sweeping avoiding overgrinding.The lay-out of the grinding bed and the wear parts, ensuring minimum of wear and eliminating the need for deagglomeration.The use of advanced electronic control (Fuzzy Logic) to save energy.The use of air transport, eliminating energy demanding external elevators.The basic concept for this ring and roller mill (CEMAX) is uniform compression and grinding in a well defined grinding zone, a high degree of internal material conveying and fully air sweeping of the mill.For this mill, the compression and grinding zone is established between the inner surface of a stationary ring rotating at subcritical speed and the surface of a stationary, but rotating roller located inside the grinding ring. Scoop devices are attached at each end of the rotating grinding ring.As the mill is running at subcritical speed, the material will leave the scoop devices at various positions ensuring a good material distribution over the cross section of the mill. To ensure grit separation inside the mill each side are provided with symetrical air inlet and outlets for transport of suspended material to the external separator. The finished product will as usual be leaving the separator through the outlets for transport of suspended material to the external separator.The finished product will as usual be leaving the separator through the outlet and be precipitated while the reject together with new feed will be returned to the mill.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Tailoring ODS materials processing routes for additive manufacturing of high temperature devices for aggressive environments' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Europe’s industry is facing many challenges such as global competition and the big change towards energy and resource efficiency. topAM can contribute to these demands by development and application of novel processing routes for new oxide-dispersoid strengthened (ODS) alloys on FeCrAl, Ni and NiCu basis. Novel ODS materials offer a clear advantage for the process industry by manufacturing e.g. topology-optimized, sensor-integrated high temperature devices (gas burner heads, heat exchangers) that are exposed to aggressive environments. Alloy and process development will be targeted by an advanced integrated computational materials engineering (ICME) approach combining computational thermodynamics, microstructure and process simulation to contribute to save time, raw materials and increase the component’s lifetime. Physical alloy production will be realized by combining nanotechnologies to aggregate ODS composites with laser-powder bed fusion and post-processing. The ICME approach will be complemented by comprehensive materials characterization and intensive testing of components under industrially relevant in-service conditions. This strategy allows to gain a deeper understanding of the process-microstructure-properties relationships and to quantify the improved functionalities, properties and life cycle assessment. This will promote cost reduction, improved energy efficiency and superior properties combined with a significant lifetime increase. The consortium consists of users, materials suppliers and research institutes that are world leading in the fields relevant for this proposal, which guarantees efficient, high-level, application-oriented execution of topAM. The industrial project partners, in particular the SMEs, will achieve higher competitiveness due to their
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Illuminating body-brain communication channels at the choroid plexus and their impact on brain physiology.' (BrainGate).

assistant: **Innovation**

In contrast to other organs, the brain is surrounded by a system of specialized anatomical barriers isolating it from direct contact with immune cells and microbial products present in the blood. However, such factors do dynamically shape brain function in homeostasis and disease. Because of this unusual anatomy, the pathways of blood-brain communication are still poorly understood, while this understanding would provide a fundamental insight into brain function regulation, and enrich the current knowledge of neurological disease mechanisms. My previous work suggests that the choroid plexus (CP) is a central player mediating the influence of immune and microbial signals on the brain. The CP epithelium is a monolayer barrier tissue, which on the side facing the blood has the ability to sense such peripheral factors, and on the side facing the brain, produces the cerebrospinal fluid (CSF)a liquid carrying nutrients and signaling molecules, which contacts nearly all brain cells, and ensures brain homeostasis. I therefore hypothesize that peripheral immune and microbial factors may shape brain function indirectly, via regulation of the CSF properties at the CP epithelium.Based on our preliminary data, and building on my past expertise in CP biology, neuroscience and immunogenomics, here I propose an interdisciplinary project BrainGate, striving to illuminate the physiological mechanisms and roles of gut-blood-CP-brain communication axis during post-natal development (Aim 1), under conditions of microbiota perturbation (Aim 2) and along the circadian cycles (Aim 3). By developing new tools for CP-specific genetic perturbation and combining them with approaches of spatial transcriptomics and behavioral readouts in mouse models, this project will reveal fundamental principles
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'The involvement of mRNA degradation and DNA damage response factors in mRNA localization during Drosophila oogenesis' in the context of a Seventh Framework call.

assistant: **Objectives**

mRNA localization and local translation is a common mechanism for efficient protein expression and function control and plays a crucial role in processes such as cell fate determination and polarity and axonal guidance. One of the better-studied systems for RNA localization is the Drosophila oocyte, in which the microtubule-dependent asymmetric localization of specific transcripts determines the fly body axes. RNA degradation and translational control factors are implicated in mRNA localization, as exemplified by the mislocalization of osk mRNA, the posterior determinant, in mutants of RNAi-associated proteins (e.g. Aub, Armi, Spn-E) and P-body components (Me31B, Dcp-1). The aim of this project is to investigate the role of the RNA degradation and translational control machinery in mRNA localization. The osk mislocalization phenotype in the RNAi-related mutants is related to the derepression of retrotransposons and consequent activation of the DNA damage checkpoint and of Mnk/Chk2. Our data suggest, however, that the phenotype is ultimately due to an impaired actin mesh and consequent premature ooplasmic streaming. I will therefore study the molecular link between DNA damage checkpoint activation and premature ooplasmic streaming, using Drosophila genetics and biochemical and molecular biology tools. Candidate players in the process are, obviously, actin regulators, but also the translation regulators Orb/CPEB and Bic-C, since premature ooplasmic streaming also occurs in hypomorphic orb mutants and in Bic-C overexpression. P-body components colocalize with osk mRNA at the posterior and are genetically required for proper osk mRNA localization, suggesting that they play a role in osk mRNP formation and/or transport. In order to study the relationship between P-bodies and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'EUropean and National CASE Law and Legislation Linked in Open Data Stack'.

assistant: **Innovation**

EUCases will develop a unique pan-European law and case law Linking Platform transforming multilingual legal open data into linked open data after semantic and structural analysis. It will reuse the millions of legal documents from EU and national legislative and case law portals, and open access doctrinal work. The developed components cover the entire publication stack: we collect the data from institutional portals, enrich them using partner's or open source language technologies and ontologies, and publish the documents as linked open data in XML, with metadata and legal ontologies in RDF, to facilitate access, navigation, multilingual search and reuse.Two SMEs from the legal information provision sector will develop, supported by the research partners, a portfolio of innovative data analysis and language technology components to enrich legal documents, transforming research into innovative high tech value-added services and products in the SMEs' global market. Two end-user applications will prove the viability of the platform. The ConsumerCases online service will provide access to a multilingual collection of national court decisions linked with EU and national legislation and doctrine in the area of consumer protection law. EULinksChecker will interactively assist legal professionals while editing or browsing documents by identifying and establishing connections with regulations and legal ontologies.With 64% of the EU contribution for SMEs, the project responds to the EU's priority for the establishment of a single European legal order" by the "availability of national databases on national court rulings concerning Community law". It exploits data from public bodies as envisaged by the PSI Directive and EC Open Data Communication. In a market dominated by few big
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Improving the safety of oral immunotherapy for cow's milk allergy in children', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Background: Food allergy affects 6% of children in the EU, and has a major impact on quality of life, nutrition, health-economics and the food production industry. Cow’s milk (CM) is a common cause, and can be particularly problematic due to the ubiquitous nature of CM in foods. Strict dietary avoidance is difficult to achieve, and unpredictable life-threatening accidental reactions are common, leading to anxiety and social restrictions for patients and families. Oral immunotherapy (OIT) has been shown to be efficacious but is not widely accepted as routine treatment, due to significant safety concerns – allergic reactions are common, and can be particularly severe in CM-OIT.   Objective: To improve the safety of OIT for CM allergy. Proposed methods: WP1 - Systematic review of the literature to identify features of published OIT protocols that are associated with improved safety. WP2 - Assessment of human immune responses to candidate modified CM proteins (proven to be both non-allergenic and tolerising in murine models) as potential tools for immunotherapy. WP3. Phase 2/3 clinical trial to assess whether a sublingual pre-treatment phase can improve the safety of OIT in CM allergic children. Deliverables: 1) Systematic review to identify features of CM-OIT associated with improved safety. 2) Evidence on the immunogenicity of candidate modified CM proteins in humans, which will reflect their suitability as immunotherapy agents in the future. 3) Data relating to whether an initial sublingual phase can improve the safety of CM-OIT. 4) Pilot data on mechanisms underlying the immune-modulation induced by OIT. 5) Skills transference to the applicant to become a highly qualified independent researcher, with expertise in OIT for food allergy at an International level. 6) Consol
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Optimization of the corrosion resistance of Friction Stir Welds in High Strenght Aluminium Alloys'.

assistant: **Innovation**

This project will seek to establish the corrosion mechanism of friction stir welds in 7075 alloy and develop technical solutions and guidelines for improving the corrosion resistance of FSW welds in 7075 alloy. These objectives will be achieved through FSW process optimisation, mechanical testing, corrosion testing and microstructure characterisation. FSW welding trails will be carried out to develop procedures for achieving high quality welds in 7075 alloy and establish the effects of process parameters on the microstructure and mechanical properties of the weld. Different corrosion tests will be carried out to establish corrosion mechanism and generate technical data on corrosion and stress corrosion cracking behaviour of FSW welds in 7075 alloy. Microstructural evolution during FSW welding will be examined to establish characteristics of microstructures in different regions of the welded joint and their responses to corrosions/cracking. Technical solutions and practical guidelines for improving the corrosion resistance of FSW welds in 7075 Al alloy will be produced based on the results achieved.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Novel technologies for on-site and remote collaborative enriched monitoring to detect structural and chemical damages in cultural heritage assets' (ChemiNova).

assistant: **Concept**

What if EU citizens could collaborate with scientists in the preservation of cultural heritage? Could conservation professionals be provided with actionable technologies, skills and frameworks that upgrade their efficiency? Europe's cultural heritage is a rich and diverse melting pot of traditions, monuments and communities where we have boiled our identity, well-being and sense of belonging. Nonetheless, in recent years, we have witnessed a series of natural and human-induced disasters that threaten it. Improving cultural heritage resilience to climate change and anthropogenic hazards requires a shift in conservation practices towards more holistic ones. ChemiNova aims to develop an intelligent computational system that goes beyond current technologies to improve the conservation, analysis and monitoring of European cultural heritage assets. Using a myriad of data, we will tackle structural and chemical damages, focusing on two specific human-induced threats: climate change and civil conflicts. Furthermore, our impact lies in the fact that we will not build an ad hoc device, but our technology is adapted so that anyone can access it from anywhere. We will involve local communities in conservation practices, from providing data (citizen science) to raising awareness on the effects of climate change, natural and human hazards affecting CH. As a main objective, we will develop novel and cost-effective ways for remote and on-site monitoring of cultural heritage assets by reusing existing technologies and providing conservators with advanced analysis of structural and chemical damages due to human-induced threats. Also, it will involve heritage practitioners and non-experts in conservation processes, while considering end-users at the centre of our tools and methods. ChemiN