RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Mediterranean afforestation and the loss of mountain cultural landscapes: the case of Zagori' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Despite summer wildfires and the expansion of urban and agricultural areas, Mediterranean mountains have experienced extensive afforestation during the last 70 years. This has largely been a consequence of the abandonment of these areas and the loss of their traditional management strategies. Afforestation processes not just imply an important heritage loss as cultural landscapes disappear under the forest without having been studied but they also boost wildfires, as traditional ways of managing the forests were not replaced by proactive forest monitoring. UnderTheForest will study the cultural landscape under threat of afforestation and already afforested in the area of Zagori (Greece), identifying and dating its human and natural elements and linking them to specific historical and socioeconomical processes. Despite being considered an area of exceptional natural heritage, Zagori’s cultural management has focused on its villages and their architectural elements, overlooking the landscape that sustained them. UnderTheForest will provide important data for Zagori’s ongoing bid for the UNESCO World Heritage Site as a Cultural Landscape. In order to do so, UnderTheForest will develop an innovative remote sensing workflow joining photogrammetric reconstruction for historical aerial imagery (1945 onwards), machine-learning probabilistic classification of multitemporal, multisource satellite imagery, and drone-based lidar survey (which will be able to locate structures under forest cover). Together with more traditional archival research, pedestrian survey, trench excavation and radiocarbon dating, the project will identify and contextualise the cultural assets that made this landscape unique and provide new tools that can be applied to other areas currently under afforestat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Genetic Pathways for the Prediction of the Effects of Ionising Radiation: Low Dose Radiosensitivity and Risk to Normal Tissue after Radiotherapy' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

Radiation protection of low dose ionising radiation is currently based on linear extrapolation from high doses. Estimates of risk from radiation exposure are based on the mean exposure to a population. The effectiveness of radiotherapy (RT) for many tumours is dose limited to minimise late effects in normal tissue. Clinical observations of adverse effects indicate large variations in individuals. Strategies linking normal tissue and various phenotypical responses at high doses to predict individual risk of normal tissue response have not been successful.The internationally leading, EU funded GENEPI-ENTB provides a valuable resource on normal tissue effects in a large cohort of RT patients. The objective is to couple analysis of cellular responses at low dose with the GENEPI bio-bank, providing an ideal opportunity to address whether differential genome-wide expression responses induced at low dose and inter-individual genetic differences are associated with the development of severe, normal tissue effects.The team of leading European clinical and basic scientists will address the objective by concentrating on non-irradiated skin biopsies or T-cells from breast cancer patients in the GENEPI databank by:i) identify two groups of patients (non- and over responders) who are statistically different in their normal tissue response to RT,ii) taking into account national regulations, ethical guidelines and patient consent, non-irradiated skin biopsies and blood will be collected to establish fibroblast and T-cells and used toiii) undertake genotyping and functional analysis after low dose andiv) retrospective analyse for correlations between the genetic and functional findings to the severity of normal tissue responses.The knowledge obtained from combining the data from approac
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Elucidation of light signaling pathways that control the photoperiodic induction of flowering' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Plants often flower in response to environmental signals. Day length controls flowering in many specie,s enabling seasonal control of flowering and adaptation to life at particular latitudes. In the model species Arabidopsis, a regulatory pathway required for the initiation of flowering has been identified and many of the components are conserved in distantly related species, suggesting its importance throughout the plant kingdom.In Arabidopsis the CONSTANS (CO) and FT proteins play an important role in this pathway, and strongly promote flowering. CO activates the transcription of FT, but only under long day lengths. This occurs because CO protein is activated by exposure of plants to light, and the time of CO transcription is controlled, so that the protein is present in light only under long days.The trainee proposes to define the molecular mechanism by which CO protein is activated by light, by identifying mutations that prevent this and then cloning the affected genes. This will be facilitated by materials available in the host laboratory: plants carrying a fusion of the FT promoter to luciferase and CO expressed from a viral promoter.Using these materials, mutations will be identified that reduce activation of FT by CO by identifying plants with reduced luciferase expression. The genes will be isolated by map-based cloning, and the function of the proteins in light signalling investigated. The host laboratory has the infrastructure required for these studies, including high-throughput luciferase detection systems.Training of the applicant will occur within an international institute and a host laboratory experienced in training foreign postdoctoral fellows, and will include laboratory-based work, oral presentations and seminar programmes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Permanent magnet generator 500 KW wind turbine', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Objectives  The objective of the project is to finalise the design, manufacture, operate and evaluate a 500 kW wind turbine with a directly driven generator distinguished by permanent magnet excitation and modular stator and rotor elements. The generator will be tested both in laboratory and in the turbine.  The project consists of the following tasks: 1. General design and manufacture. 2. Final electrical design of generator. 3. Electrical system (less generator) and control. 4. Generator design and manufacture. 5. Generator testing and electrical modelling. 6. Evaluation.  Technical approach  The proposal is based on an earlier Joule2 project, which was conducted in co- operation with six European universities and one private company. After an evaluation of the five candidate designs, one proposal was selected for a final design of a 500 kW generator and the application of an available conventional 400 kW wind turbine design to this generator. The project included building of a 40 kW test generator of the selected concept..  The generator design is characterised by modular rotor and stator elements, that may be produced in quantity without any large scale facilities. The magnets are of ferrite type furnished with laminated iron flux concentrators. The stator elements consist of an E-core lamination with a single coil. The design is protected by a patent. The generator is connected to the grid by means of an AC-DC-AC link.  Expected achievements and exploitation  In general the project will be carried out as an ordinary industrial wind turbine development project including design, manufacture, erection, commissioning and evaluation. The main difference is that the project also includes the development of the directly driven generator and its electrical and control syst
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Advancing Innovative Stem Cell-based Therapy for Diabetes in Europe' (ISLET), addressing dissemination and exploitation.

assistant: **Impact**

Type 1 diabetes (T1D) is one of the main health challenges, with 6 million European citizens affected. Today, T1D accounts for a severe economic burden on healthcare and labour force. To bring advanced therapy in type T1D to patients, a scalable source of pancreatic islets for transplantation is needed. The objective of the ISLET project is to build and implement a new and innovative program for the production and marketing of human pluripotent stem cell (hPSC)-derived advanced therapy medicinal products (ATMPs) for treatment of EU citizens with T1D. To achieve this, ISLET gathers a constellation of experts to establish a transferable GMP-compliant manufacturing program based on improved and standardised protocols for generation and characterisation of future ATMPs. Furthermore, to make a product closer to the “golden standard” human pancreatic islet, ISLET will develop islet-like clusters composed of isolated hPSC-derived alpha and beta-like cells, and advance strategies for safe, up-scaled production and a quantitative go/no-go assessment of therapeutic quality. Specifically, to overcome the lack of robust qualitative and quantitative assays to assess islet function, ISLET will introduce a novel quality control concept for predicting the therapeutic efficacy by quantitative proteomics and lipidomics as part of the ATMP development chain - a concept that will be widely applicable. A commercial route for exploitation of HESC derived ATMPs for T1D treatment with EU will be developed. Finally, a professionally supported dual plan for public engagement in the fields of stem cell therapy and diabetes is rounding up the project.


**Keywords:** Type 1 diabetes, human pluripotent stem cells, ATMP, GMP-manufacturing program, insulin, beta cells, islets, ATMP quality control, o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Hotspot ecosystem research on the margins of European seas'.

assistant: **Objectives**

HERMES is designed to gain new insights into the biodiversity, structure, function and dynamics of ecosystems along Europe's deep-ocean margin. It represents the first major attempt to understand European deep-water ecosystems and their environment in an integrated way by bringing together expertise in biodiversity, geology, sedimentology, physical oceanography, microbiology and biogeochemistry, so that the generic relationship between biodiversity and ecosystem functioning can be understood. Study sites will extend from the Arctic to the Black Sea and include open slopes, where landslides and deep-ocean circulation affect ecosystem development, and biodiversity hotspots, such as cold seeps, cold-water coral mounds, canyons and anoxic environments, where the geosphere and hydrosphere influence the biosphere through escape of fluids, presence of gas hydrates and deep-water currents. These important systems require urgent study because of their possible biological fragility, unique genetic resources, global relevance to carbon cycling and possible susceptibility to global change and man-made disturbances. Past changes, including catastrophic events, will be assessed using sediment archives. We will make estimates of the flow rates of methane from the geosphere and calculate how much is utilised by benthic communities, leaving the residual contribution to reach the atmosphere as a greenhouse gas. HERMES will enable forecasting of biodiversity change in relation to natural and man-made environmental changes by developing the first comprehensive pan-European margin Geographic Information System. This will provide a framework for integrating science, environmental modelling and socio-economic indicators in ecosystem management. The results will underpin the development of a c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Realistic and Informative Simulations with machine learnING' to be submitted under Horizon 2020.

assistant: **Abstract**

Contemporary astronomical research relies heavily on simulations. However, the current state of the art has no objective way to measure how `realistic’ a simulation is, nor how informative it is with respect to the scientific questions it was designed to address. Comparison between simulation and observation is left to the subjective judgment of the individual researcher. The set up of simulation sets, the choice of parameters and ingredients to include, and the number of runs to execute are all also left to the researcher’s preferences, given hardware constraints. Numerical astronomy has, as of now, no shared standard of experiment design. Additionally, numerical simulations are often so slow and expensive that it is impossible to quickly and cheaply produce new outputs to improve statistical significance or for rapid prototyping new techniques.  To address these issues, I will develop the RISING framework. RISING (Realistic and Informative Simulations with machine learnING) is a bundle of machine learning tools: anomaly detection tools to measure the realism of simulations, active learning tools to plan optimal sets of simulations under resource constraints, and generative modeling tools to obtain credible simulation outputs without running the underlying simulation.  RISING will find immediate application on dynamical simulations of star clusters and hydrodynamical simulations of their parent clouds, which are being run in large numbers by the ERC-funded DEMOBLACK group led by my host, Prof. Michela Mapelli. RISING will be written in Python 3.7 using the Keras API on top of Tensorflow, integrated with frameworks for multi-scale, multi-physics simulations, such as AMUSE , whose author is Prof. Portegies-Zwart (Leiden Univ.) with which Prof. Mapelli has a current ongoi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Western Strategies in East Asia. The Reconfiguration of US, British and French security policies in the Pacific Century' (WESTRAT) under Horizon 2020.

assistant: **Objectives**

The core question that this project tackles is how the three major Western military powers (the US, Britain and France) have adapted their security policies to the shifting center of strategic gravity of international politics from the Euro-Atlantic area to the Asia-Pacific. In addressing this question, WESTRAT conducts a comparative analysis of their evolving security policies in confronting the main “traditional” and “non-traditional” security challenges in East Asia, i.e. the rise of China, the proliferation of weapons of mass destruction and piracy. In so doing, this project makes three original contributions. (1) Firstly, WESTRAT offers an empirical contribution as the first work to provide a cross-national comparison of the security policies of the three major Western powers (1990-2016) – in their national, bilateral, and multilateral configurations – in what is deemed to be the world’s new center of strategic gravity. It therefore investigates a crucial yet under-explored dimension of contemporary international politics. (2) Secondly, it provides an innovative conceptual framework that sheds light on the emerging networks of national, bilateral and multilateral security arrangements (what we label “networked security postures”) in international politics. It thereby contributes to the debates on the under-theorized relationships between bilateralism and multilateralism as venues for security cooperation. (3) Finally, given the absence of a common European strategy toward the region, this project seeks to enrich the policy discussions in the European Union (EU) and to provide policy recommendations on how to bolster cooperation between the EU, its member states, and the US – and transatlantic relations more generally – in developing a common strategy towards the (r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Advanced Manufacturing of Multi-Material Multi-Functional Products Towards 2020 and Beyond' (4M2020).

assistant: **Innovation**

4M2020 is focused on building upon the durable integration mechanisms/structures and innovation chains created within three levels of project clusters in the field of multifunctional miniaturised products and their applications in energy, medical, optoelectronics and microoptics, printed electronics and ultra precision engineering industrial sectors that led to the creation of long term R&D+I partnerships.4M2020 will facilitate cross fertilisation of product centred advanced manufacturing platforms along five R&D+I streams and thus create alliances based on interrelated technological research and product demonstration activities and add value to its stakeholders by establishing R&D+I environment for combining KETs heterogeneously in the context of specific technology and product requirements.The four main objectives of 4M2020 are the:• Cross fertilisation of product centred advanced manufacturing platforms• Formation and development of new networks and alliances• Advancement of innovation chains• Assessment of the maturity of application/product focused advanced manufacturing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'A novel, autonomous and REVersible Inflow control VALve to increase oil production and reservoir recovery rate by stopping the production of unwanted water and gas locally in the reservoirs' (REVIVAL), addressing dissemination and exploitation.

assistant: **Impact**

REVIVAL focuses on the problem of maximising recovery of oil from wells and prolonging their productive life; a commercial imperative for the industry and a response to EU policies to secure Europe’s energy supply in respect to oil.Globally only 32% of available oil reserves are extracted from oil fields. A 5% increase in the recovery factor would yield as much oil as is expected from all future exploration efforts.The reason for low recovery rates is the breakthrough of water or gas in the well. The industry has addressed this by developing inflow control devices (ICD & AICD) that choke oil production both at start up and when gas or water incursion occurs; but do not stop these entering the system.Our innovative solution utilises the properties of fluid dynamics to create an Autonomous Inflow Control Valve (AICV) that, whilst remaining simple in concept, eliminates the weaknesses of AICD and ICD products. By comparison, proof of concept tests on our AICV show it will increase recovery, does not choke initial oil production, can stop gas and water completely, is autonomous, reversible, reliable and price competitive.We have established the concept, but still face significant technical challenges which we need to outsource to specialist R&D partners. These involve developing an innovative laminar flow element, filters and seals that can withstand the harsh environments in wells.REVIVAL enables our SME partnership to create a novel, highly differentiated, validated pre-production prototype that can be quickly commercialised post project completion, providing outstanding benefits for our own organisations, our oil company clients, national government exchequers and Europe as a whole. It responds to competitive threats we as SMEs face.The primary market are oil company cli