RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'A theoretical study of the adsorption of water on sodium chloride'.

assistant: **Innovation**

Research objectives and content The theoretical study of adsorption of molecules on surfaces is a field of great scientific relevance and interest. An important system is the adsorption of water on sodium chloride crystals. Adsorbed water has an important role in the chemistry of trace gases on the surfaces of sodium chloride crystals in the atmosphere. Experimental studies have only been performed at temperatures below 160K and they are not conclusive about the structure of the adsorbed water monolayer. Dr. Stones group has a worldwide reputation in studying intermolecular interactions, and has recently started to study adsorption on molecular surfaces. The aim of this study is to model the adsorption of water on the surface theoretically, and hence to investigate the structure of the water monolayer and the importance of crystal defects and ion mobility on the surface. From this study we hope to be able to draw conclusions about the effect of adsorbed water on the chemistry of sodium chloride crystals in the atmosphere. Training content (objective, benefit and expected impact) The main objective for me as a post-doctoral research worker in Dr stone's group is to obtain a broader and deeper knowledge and understanding of intermolecular interactions. This is an important field of chemistry and an extended knowledge of it would be very beneficial for me, whether I stay in the university sector or move to industry. Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Mannan-related enzymes of wheat endosperm' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

European society and economy relies on the productivity of staple food, such as wheat. Plant cell walls are a centrepiece of plant development and tuning their biosynthesis could improve the productivity and the quality of wheat grain. Although the structure of cell wall polysaccharides is relatively well-documented, little is known about their biosynthesis. The project proposes for the first time 1) to explore the structure, organisation and function of mannan, a cell wall polysaccharide that impacts on wheat grain development, and 2) to investigate the function of four putative genes involved in the mannan biosynthesis, using a combination of well established and new methodologies (enzymatic fingerprinting, FT-IR microspectroscopy and MALDI-MS imaging). This research is of potential interest to various industrial sectors (e.g., plant breeding, milling and biofuel industries) active in Europe and represents a good opportunity to improve competitiveness of European agriculture. Within the host institute (INRA, France), which is a World leader for agricultural sciences, the supervisor is internationally renowned for its contribution in the general understanding of plant cell walls. The host will offer the opportunity to the fellow to develop a sound knowledge in biochemistry and molecular biology and will contribute to improve his managerial skills. In return, the fellow who has a strong expertise in microscopy and enzymatic activity assays will implement these techniques in the host institution. The fellow will have the opportunity to disseminate his knowledge during various events towards audiences of scientists, students and the general public. The fellow will access to all the facilities, logistics, and equipment necessary for the good implementation of his project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'European Joint Programme for the Integration of Radiation Protection Research' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The proposed European Concerted Programme on Radiation Protection Research (acronym: CONCERT) aims to contribute to the sustainable integration of European and national research programmes in radiation protection. It will do so by focusing resources and efforts in five key directions:• Bring together the elements of the European scientific communities in the fields of radiation effects and risks, radioecology, nuclear emergency preparedness, dosimetry and medical radiation protection, whose joint expertise is essential to continue the development of radiation protection knowledge in a multidisciplinary mode to reduce further the uncertainties in radiation protection.• Strengthen integrative activities between the various areas of expertise, in particular biology, biophysics, epidemiology, dosimetry and modelling as well as fostering the use of existing infrastructures and education and training activities in radiation protection.• Stimulate and foster scientific excellence, by setting up and co-funding advanced research programmes with the potential to enhance current knowledge and the scientific evidence base for radiation protection.• Exchange and communicate with all stakeholders, including the professional organizations concerned with radiation protection, the regulatory organizations across Europe, the public and media where necessary, and the international community of scientific, technical, legal and other professional experts in radiation protection.• Foster the harmonious application of available scientific basis for radiation protection practices across Europe, by bringing together scientific and technical expertise in radiation protection issues, standard setting know how, particularly with respect to the implementation of the Euratom Basic Safety Standards (
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Predictive Haptic COding Devices In Next Generation interfaces' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

PH-CODING founds the next generation ultra-intuitive user interfaces, through a new branch of neuroscience and providing the first exploitation of its underlying predictive coding principles in technological solutions for human haptic interactions. The main scientific hypothesis is that any haptic interaction involves a very large number of widespread skin sensors whose signals have a relationship that is intrinsically modulated by the contact with the environment and the skin mechanics. Combined with predictive actions, the brain is thus able to generate highly enriched percepts of the interactions that we make, which yields an essential part of the brain’s development of the concept of contingencies and a rich and stimulating understanding of the physical world. Failure to reach a corresponding level of responsiveness is likely a main reason why current user interfaces in VR systems and remote control become understimulating and disinteresting to most users. PH-CODING will: Characterize the brain’s computational mechanisms for reading out sensor population code’s generated in different skin tension states in experiments with dedicated haptic interfacesDevelop a predictive coding model to extract stable haptic percepts through active interaction despite variability in the sensory signals, and demonstrate it in a robotic implementationDesign and fabricate a soft artificial eSKIN based on bendable electronics integrating a variety of micro-/nano-sensors, with the capacity to ‘perceive’ multi-dimensional user inputDemonstrate the transmission of ultra-rich haptic information generated in a man-to-eSKIN contact to a remote user via novel active haptic interfacesCarried out by leading neuroscience, nanotechnology and robotics groups and an SME at the forefront of haptics te
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Theory of particle acceleration in solar flares' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

The project aims at a theoretical understanding of the problem of particle acceleration in solar flares. In solar flares, a large number of particles is accelerated to relatively high energies over a relatively short period of time. Observations made by space missions in recent years have corroborated the suggested link between magnetic reconnection, flare energy release and particle acceleration. The theoretical details of this link still have to be worked out and that is the objective of the present project. Several acceleration mechanisms have been suggested in connection with the magnetic reconnection process in flares. The most promising are direct acceleration by parallel electric fields (DC acceleration) and stochastic acceleration by MHD turbulence. Both mechanisms will be studied in this project to assess their relative importance for particle acceleration in flares. The project will provide training by research in solar and astrophysics in general and in solar flare physics in particular. The project has a large numerical component and will thus also provide training in numerical methods and the use of modern computational facilities (parallel computers). The project will broaden the scientific background of the applicant. As the subject of the project is likely to become even more important in the near future, the career prospects of the applicant will improve considerably. The host institution will benefit from the presence of the applicant by being able to use his expertise in turbulence theory. Also the project would be an extremely welcome and necessary addition to the host's general research programme on flares.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Redefining wild-domestic boundaries in a changing landscape through the human-wolf-dog relationships' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The political and economic changes of recent decades are having an impact on the European rural environment, resulting in conflicting situations around the recovery of habitats and wildlife species (often symbolised by the wolf) and rural communities. These conflicts are being addressed by the EU through technical and economical measures but there is a general failure to recognise the importance of their social and cultural aspects. Anthropology can contribute by highlighting the overall context and the complexity of factors affecting people's perceptions of wildlife and the rural landscape. Using a multi-disciplinary approach we will examine how the domestic dog, as a victim or as a mean of protection, modulates the man – wolf conflict. This will link anthropological conceptual models and concrete attempts to address material aspects of this conflict, and to use this case study as a lens to examine wider issues associated with how rural people perceive their relationship with the various elements of the landscape they inhabit. We will conduct fieldwork using innovative methodology, crossing the traditional anthropological qualitative approach with quantitative, spatial and visual ones borrowed from other disciplines. Moreover, a cross comparison between different landscape users coming from different regions (Poland, Norway and FYROM) will help illuminate the influence of the specific set of environmental and social / cultural circumstances. The combination between 1) the scientific quality of the host institution, focused on multi-disciplinary and applied research within the fields of biodiversity conservation, natural resource management and rural development and 2) the interdisciplinary profile of the applicant, experienced in anthropological theories and fieldwork,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Physiological Role of Nonsense-Mediated Decay in Herpes Simplex Virus Infection and Pathogenicity' to be submitted under Horizon Europe.

assistant: **Abstract**

Virus infections cause a major healthcare burden worldwide. The neurotropic human herpes simplex virus 1 (HSV-1) establishes life-long latent infection in neurons, from which it frequently reactivates to disseminate within the population. Clinical complications caused by HSV-1 infections range from mild (herpes labialis) to sight- (keratitis) and even life-threatening diseases (encephalitis). Prevention and treatment of HSV-1 infections are considered a top priority by the WHO. However, development of vaccines and improved therapeutic approaches is hindered by our incomplete understanding of the virus-host interactions that govern infection and disease, especially the interplay between HSV-1 and intrinsic neuronal defenses. The highly conserved cellular RNA degradation pathway nonsense-mediated decay (NMD), which regulates expression of ~10% of cellular transcripts and controls numerous fundamental processes, has recently emerged as an important regulator of neuronal function. Based on my previous postdoctoral studies that revealed a major role for NMD in controlling infection by oncogenic human herpesviruses combined with my preliminary data on HSV-1, I hypothesize that NMD provides an intrinsic defense mechanism that controls HSV-1 infection. In this fellowship, I propose to combine my experience and the expertise of the host institute to determine the physiological relevance and molecular mechanism by which NMD controls HSV-1 infection in its natural human host. Successful completion of my project will lead to improved insight into the virus-host interactions that control infection of HSV-1, thereby providing novel therapeutic targets to combat HSV-1 infection and pathogenesis. Moreover, the extensive and multidisciplinary training in research and transferrable skill
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'New strategies to characterise genomic diversity for biodiversity conservation' (ConserVar), addressing dissemination and exploitation.

assistant: **Impact**

Genetic diversity is one of the three basic elements of biodiversity. Understanding the full extent of this diversity within species is fundamental for their conservation. However, despite the ongoing advances in DNA sequencing technologies, conservation genomics is lagging behind in using whole-genome data efficiently. In contrast, other fields, such as human genomics, have developed theoretical and computational approaches to tackle this. If applied to endangered species, these approaches will provide a better understanding of their genetic diversity, particularly regarding the structure of this diversity across populations and its effect on adaptation to changing environments.By leveraging two types of genetic data currently overlooked in conservation genomics  haplotype information and structural genomic variation, I will develop new analysis strategies to characterise genomic variation in endangered species. Using the Arctic fox as a model species, I will use whole-genome data from both present-day and historical samples to: 1) infer subtle patterns of population structure and gene flow, 2) quantify temporal changes in genomic structural variation and 3) assess the ability of these types of genetic data to inform on adaptation to local environments.This research programme will provide not only a comprehensive characterisation of genomic diversity in Arctic foxes  with a direct impact on the Swedish Arctic fox conservation programme, but also new analytical tools for conservation genomics, unlocking the full potential of whole-genome data for biodiversity conservation.Combining my solid track record on both human and biodiversity population genomics, and the hosts extensive expertise on conservation genomics and palaeogenomics, this fellowship will allow me to obtai
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'National identity and immigrants in Southern Europe - the role of public discourse' to be submitted under Fourth Framework.

assistant: **Abstract**

Research objectives and content The current decade has been characterized by a significant increase in immigration towards the European Union and in particular towards its southern Members, namely Greece, Italy and Spain. A large part of the newcomers, although illegal, have already settled down in these countries. Moreover, xenophobic attitudes have risen, in Greece and Italy in particular, while ethnic or racial discrimination has become increasingly common. Research on these new migratory trends has to date concentrated on immigration control rather than integration. In particular, little attention has been paid to the relationship-between national identity and the development of xenophobic or discriminatory attitudes towards immigrants. This research project will examine the role that public discourse plays in fostering this type of attitudes and behavior. The analysis will concentrate on the role that policy actors discourse plays in emphasizing the distinction between us" (nationals) and "them" (foreigners immigrants). The implications of discriminatory public discourse for immigrant acceptance and integration will be discussed. Training content (objective, benefit and expected impact) The training to be obtained by the host institution (IPCNR) will concentrate on methods of analysis of non-verbal behavior in discourse (with particular reference to tape- and video-recorded material) and context sensitive interviewing techniques "
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Role and Modulation of Jak and STAT signaling in Graft Rejection and Graft versus Host Disease' (2007-2013) targeting Seventh Framework.

assistant: **Abstract**

Our interest is to extend the understanding of Jak and STAT signaling in the immunologic processes conditioning the outcome of allogeneic hematopoietic stem cell transplant  (allo-HSCT) and to develop new strategies to overcome graft rejection (GR) and graft versus host disease (GVHD).Allo-HSCT is a potentially curative strategy for many patients. GR and GVHD hamper the success of allo-HSCT by conditioning treatment related mortality. The Janus family of kinase (Jaks) dictates T helper (Th) cells differentiation through the activation of different members of the STAT family.We hypothesize that Jak and STAT signaling play an important role for mediating GR and GVHD and propose to: 1) evaluate the activation of Jaks and STATs after transplant in patients with or without GVHD; 2) analyze the kinetics of activation of Jaks and STATs in mouse models of GR and GVHD; 3) determine whether Jak3 has a non-dispensable role in alloreactive-driven, such as GR and GVHD, or homeostatic-driven T cell expansion; 4) explore the possible interaction between STAT6 and STAT1 to dictate Th differentiation; 5) modulate GR and GVHD through the pharmacological manipulation of Jak signaling.We plan to achieve these objectives by an inter-disciplinary approach consisting of the analysis of in vitro experiments, in vivo data and clinical data. Jak and STAT signaling will be studied on lymphocytes form patients undergoing allo-HSCT. In parallel, in vivo mouse models will explore the role of different Jak-STAT molecules in the onset of GR and GVHD by PCR, phospho-flow cytometry and western blotting. We will utilize mice deficient for different Jak-STAT molecules to demonstrate the causal role of these proteins in GR and GVHD. These mouse models will be instrumental to test the efficacy of new drugs