RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Medium range Ultrasonic inspection technique for detecting micro-biologically induced corrosion in automatic fire sprinkler systems'.

assistant: **Objectives**

The installation of sprinklers can result in substantial reductions in insurance premiums and so insurance companies are becoming increasingly interested in their proper installation and function. For example, the British Automatic Fire Sprinkler Association has abundant evidence about the effectiveness of their members’ technology in reducing loss of life and property in office, residential, retail, storage, public venue buildings and in special sites such as ships, control rooms and hospitals.The proper functioning of fire sprinkler systems can be catastrophically undermined by corrosion. The water in the system pipes is stagnant and, if inhibitors are inactive, then this can give rise to microbiological induced corrosion (MIC), which leads to leaks. This corrosion is localised and is not evident in close visual inspection until the leak starts. Moreover the pipes are often enclosed and difficult to access for close viewing. MIC may occur in both dry and wet sprinkler systems.Long range ultrasonic testing (LRUT) has been developed for screening long lengths of pipe (up to 100m from one test location) for corrosion, especially in otherwise inaccessible areas. It has been used to a limited extent on the feeder pipes and risers in sprinkler systems. However, the pipe lengths are too short (typically <5m) and the defects too small in comparison with the ultrasound wavelengths for current LRUT systems. Moreover the numerous features such as pipe elbows and branches, makes interpretation of ultrasound echo-signals difficult.SprinkTest aims to inspect automatic fire sprinkler systems by developing a medium range ultrasonic test (MRUT) system, using higher frequency ultrasound (100KHz -500KHz), smaller flexible transducers to gain access to confined spaces, lower power electr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Use of adoptive T cell transfer in combination with oncolytic adenoviruses for cancer treatment' in the context of a Seventh Framework call.

assistant: **Objectives**

Metastatic cancer remains an incurable disease in the majority of cases and thus development of novel treatment strategies is required. Adoptive T cell therapy is a promising therapy for patients with a wide range of cancers. This therapy involves ex vivo activation and expansion of T cells followed by infusion into patients. Peripheral blood CD4+ and CD8+ T cells can be redirected against tumor-associated antigens (TAA) by genetically modifying them with chimeric antigen receptors (CARs). Commonly, CARs consist of an antibody-based external receptor structure coupled to an intracellular signaling domain. Recent clinical studies using CAR-modified cells have established the feasibility and safety of this strategy in human patients. However, several hurdles have still to be overcome for a successful tumor treatment with this therapy. First, infused CAR-modified cells have short persistence in the host, limiting antitumor responses. And second, tumor creates a strong immunosuppressive environment that can impair the efficacy of infused T cells. Our hypothesis in the proposed program is that persistence and efficacy of genetically modified T cells in cancer patients can be increased by: (1) choosing the “right” T cell subset candidate (2) improving the signaling endodomain of CARs, (3) breaking tumor immunotolerance. In this regard, we propose that oncolytic adenoviruses, whose replication has been restricted to malignant cells, can be used to enhance tumor immunotherapy as they offer (a) tumor debulking and (b) danger signals that elicit strong immune responses.In order to test these hypothesis, the proposed program aims to (1) evaluate the contribution of different costimulatory signalling domains to CAR T cell function, (2) compare the in vivo engraftment, trafficking,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'European Virus Archive GLOBAL' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

EVA-GLOBAL gathers 38 academic institutions at the forefront of human, animal and plant research in Virology, associated with key Non-Governmental Organisations including the World Health Organisation, OIE, FAO and related international organizations such as the CGIAR. This new project is built on the strong foundations constituted two previous EVA (2009-2014), FP7 and EVAg (2014-2019), H2020 projects. It includes high calibre institutes with the appropriate expertise to collect, characterise, standardise, authenticate and distribute human, animal and plant viruses. EVA-GLOBAL is conceived to be an open access entity aiming at developing synergies and complementary capabilities in such a way to offer an improved access to the researchers. A single-entry point, the web-based catalogue, gives a facilitate access to the end-user, to the collections including viruses, derived materials and engineered cells. This project will integrate 13 facilities dedicated to the high-risk pathogens manipulations (BSL4), which constitutes the largest BSL4 network worldwide. EVA-GLOBAL will also link up with other network-based virus associated programmes that exist globally. This unique advanced community aims at becoming the most responsive network to improve the control of emerging or re-emerging virus outbreaks at the global level. During the past EVAg project, this infrastructure has already been able to play a key role for the control of emerging virus diseases by the supply of unique reagents for the detection of viruses under the WHO umbrella. Through this new ambitious four-year project and the new institutes joining the consortium, EVA-GLOBAL will become the largest virtual virus collection for human, animal and plant viruses will move beyond the current state-of-the-art to provi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Hierarchical Functionalization of Graphene for Multiple device fabrication' in the context of a Seventh Framework call.

assistant: **Objectives**

This project is based on the application of layer-by-layer (LbL) technology for the development of a versatile and generic procedure for the fabrication of hybrid devices involving graphene and materials of a different nature such as polymeric, organic,  and inorganic entities.  The project aims to achieve the organization and integration of graphene sheets with heterogeneous components of different sizes and compositions into higher level structures/assemblies and devices. Components include polymer molecules, magnetic nanoparticles, nanorods and quantum dots.The development of new design principles and methods to control  tunable dimension at the nanoscale, structure and property complexity of graphene.  The project aims to integrate, graphene, with inorganic particles and polymeric and organic species to develop building blocks for assembly and to understand the principles underlying their interaction.  The projects aims to integrate graphene assemblies into anticorrosive coatings and devices for opto electronic applications and energy conversion
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Optimisation of liver and intestine in vitro model for pharmacokinetics and pharmacodynamics studies' in the context of a Sixth Framework call.

assistant: **Objectives**

The EU White Paper 'Strategy for a future chemical policy¿ proposes to harmonise the testing requirement for existing chemicals, by developing a new system for the Registration, Evaluation and Authorisation of Chemicals" (REACH). Given the existing regulation, this could result in a large increase in animal use. Thus, the need of reliable alternative in vitro models becomes urgent. Although several in vitro models are available, they are not yet accepted into regulations, as they still require better characterisation and optimisation to reach the validation stage.The main aim of this project is to provide optimised established protocols and experimental in vitro models for testing intestinal and liver absorption, metabolism and toxicity of molecules of pharmacological interest. The added value of the project is to provide optimised sequential procedures, easily amenable to validation studies for screening and testing of new drugs, possibly by miniaturized and automated technology. The direct participation of SMEs in the research activities will assure that those procedures will also fit with the requirements of industrial application. The project is articulated in integrated work packages and research objectives, interacting at various levels. Different liver and intestinal cellular models will be optimised for applications that are relevant to the drug development process.The optimised models will be challenged with structurally diverse reference drugs, chosen with the help of a steering committee of relevant stakeholders, to develop innovative methods to assess their transport, metabolism and toxicity. New advanced "omics" technologies will allow "in vitro/in vivo" comparisons, produce reference standards for the validation of cellular models and develop high throughp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'An Integral Platform for the Early Diagnosis of Skin Cancer' (2014-2020) under Horizon 2020.

assistant: **Objectives**

DermoSafe® is an integral platform based on DermoBrain, a cognitive computing system which will enable the earlydetection of skin cancer for broad population. The ICT-based approach facilitates and speeds the professional analysis ofpotential skin lesion by employing Dermoscopy Imaging. DermoSafe provides an accurate tool that allows patient performingthe needed increased analysis to combat the exploded incidence of skin cancer without the requirement of an appointmentwith general practitioners or dermatologists, reducing lead time of the skin analysis results from 42 to 3 days. Hence, patientuncertainty and anxiety is clearly diminished. Furthermore, DermoSafe enables a fast and easy access to Dermoscopyexperts to the healthcare professional community (pharmacies, general practitioners and dermatologists). DermoSafe hasdemonstrated capability to overpass the limitations posed by current Dermoscopy devices for early and broad screening byavoiding the need of a high investment to buy the equipment as well as offsets the lack of specialised dermatologyworkforce. Once implemented in the healthcare system and at pharmacies, DermoSafe can reduce the skin cancer budgetup to 136,000€/patient. Since our platform and associated service will make the use of Dermoscopy imaging as broad as theuse of a thermometer, the business opportunity seems unquestionable. The objective of this project is the furtherdevelopment of DermoBrain, to enable (1) skin lesion pattern recognition and identification for automatic history tracking andevolution rating, (2) automatic image quality check, and (3) image automatic classification considering also the patientmedical context by artificial intelligence. By deploying DermoSafe platform in Europe, we aim to achieve a cumulative cashflow of 10.7 M€ b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Using cosmic rays for better, more portable and efficient analysis and detection for customs' to be submitted under Horizon Europe.

assistant: **Abstract**

The number of goods and parcels shipped is growing with unstoppable speed. With more individual shipments the means of logistics have changed from central locations to small logistics companies, postal agencies, airports, ports, private vehicles etc. However, the analysis and detection capabilities of such locations are very low, making it an easy target for transporting illicit goods.Currently, there are no effective technologies available that would be able to cope with this growing problem. Despite the widespread use of X-ray technologies, they are still inefficient when it comes to mobile scenarios. In addition, their detection capability is based solely on visual imaging with no way to examine the exact material content of small shipments.We are proposing a completely novel, yet highly effective solution for this. The CosmoPort project will develop the next generation of scanner systems using Atmospheric Ray Tomography (ART). Such systems are equipped with advanced Machine Learning-based risk assessment tool. As muon tomography itself is a technique already in use, then we will develop the first mobile solution combined with AI/ML tools to enhance material and object classification for the first time ever.


**Keywords:** atmospheric ray tomography, drug detection, mobile scanners, drug analysis, postal services,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Sweden EEN consortium Innovation Support 2020-2021' to be submitted under Horizon 2020.

assistant: **Abstract**

Successful growth companies tend to be significantly better at innovation management than average. However, most SMEs and SME support organisations consider the inability to manage innovation processes efficiently and effectively as one of the most important barriers to create European economic impact (competitiveness, growth and jobs) from innovation activities in SMEs.  The objective of this project proposal is to address these problems by providing services enhancing the innovation management capacity of SMEs wishing to develop innovation projects with a strong European or international potential.  All three partners active in this proposal are partners in Enterprise Europe Network under COSME (SweNet) to assure fully integrated services and a true one-stop-shop for business and innovation support to SMEs. Consequently, synergies with COSME activities are easily identified. All innovation experts will also have a role as both KAM and EIMC providers and synergies will be handled effectively. Each client specific needs will be prioritised during the client journey ensuring that we will make the best use of our resources, including the local, national and EU ecosystem.


**Keywords:** SME Instrument, EIMC services, Innovation Health check, IDD4SME
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Enable RPAS Insertion in Controlled Airspace' (2014-2020).

assistant: **Concept**

Remotely Piloted Aircraft Systems (RPAS) have positively impacted civil and military applications. RPAS access to non-segregated airspace is essential to exploit their full capabilities, offering new services to the community and enabling market opportunities with huge economy benefits. To make insertion of RPAS into the ATM system a success, key challenges have to be addressed: to design a harmonised way to operate in nominal and emergency conditions; that RPAS do not adversely impact operations of existing airspace users; to ensure interoperability with current safety nets; to develop common standards and procedures.ERICA will assess operational and technical capabilities to allow RPAS to safely operate (in nominal and emergency conditions) in controlled airspace (class A to C) and will develop and validate solutions without negative impacts on air traffic. A Detect and Avoid system for the “collision avoidance” and “remain well clear” functions will be developed. A framework for inserting RPAS into the non-segregated airspace will be developed in two streams: “Accommodation”, with platforms, missions and applications to meet the initial demand, exploiting existing capabilities, and “Integration”, to reach the final objective.The benefits expected from the project are: developing recognised European RPAS operations in non-segregated airspace; enabling civil and military RPAS, fixed and rotary wing aircraft, to operate mixed with the manned traffic under a single European sky; increasing RPAS access to the airspace and equity with conventional traffic; contributions to regulatory and standardisation bodies; assuring interoperability with ATM system within and outside Europe; Safety, Human Performance and Cyber Security KPAs will also be investigated.The ERICA partnersh
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'TWINNING FOR EXCELLENCE TO ADVANCE RESEARCH IN THE ACTIVATION OF ANTI-TUMOR IMMUNE RESPONSE AFTER ELECTROCHEMOTHERAPY COMBINED WITH GENE ELETROTRANSFER OF pDNA ENCODING ICIs' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

More than a decade has passed since the first immune checkpoint inhibitor (ICI) was approved for the treatment of advanced melanoma, marking the beginning of immunotherapies in cancer treatment. However, even in the best scenarios with a combination of ICIs and standard therapies, durable benefit is not achieved in about half of patients. Therefore, new approaches are needed on how best to exploit the potential of ICIs. The scientific aim of the ZAP cancer project is to determine how a local ablative technique, electrochemotherapy with BLM, CDDP or OXA induced immunogenic cell death (ICD), can be combined with gene electrotransfer of pDNA encoding ICIs to elicit a systemic anti-tumor immune response. The ZAP cancer project plans to improve access to scientific excellence, optimize research management and accelerate the exchange of personnel, knowledge and ideas in the European Research Area (ERA) and the two participating institutions from the widening countries; the Institute of Oncology Ljubljana (IOLJ) and the Faculty of Health Sciences (FHS) of University of Ljubljana. ZAP cancer will expand the existing collaborative network with three leading European institutions: Institute of Pharmacology and Structural Biology, a department of the CNRS (IPBS-CNRS), Toulouse, France, Katholieke Universiteit Leuven (KUL), Leuven, Belgium, The Institute of Translational Pharmacology, Institute of the Italian National Research Council (CNR) and a new partner: The Medical University of Graz (MUG), Graz, Austria. Through the proposed project, a multidisciplinary network of cancer research centers will collaborate to establish a state-of-the-art, high-throughput multi-omics in vitro and in vivo research platform at IOLJ and FHS that will provide them with valuable new expertise and kn
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'MXene Nanosheets For Future Optoelectronic Devices'.

assistant: **Innovation**

MXenes, a new family of transition metal-based 2D materials, have garnered a lot of interest due to their intriguing propertiesand potential in many applications. Recently, they have exhibited impressive optical properties such as broadbandabsorption and surface plasmon excitations, underlining their potential for photonic and plasmonic devices. At this earlystage of development, large scale synthesis and processing of MXenes is lagging behind other 2D materials, leaving theopportunities for optoelectronic applications nearly uncharted. Therefore, this project proposes to investigate using MXenesfor optoelectronic memory applications. In particular, the project proposes three main activities that capitalise on the strengthof experienced researcher and the host research group (Prof. Andre Geim) in 2D material synthesis and optoelectronicdevices: (1) development of processes to synthesise new MXenes, (2) development of doping strategies to functionalise MXenesand (3) development of optoelectronic memory device for image capture, where plasmonic and photosensitivity of MXeneswill be exploited. The synthesised MXenes will be characterised using various advanced microscopy and spectroscopytechniques. The result of the proposed project will be transformational functionalities with orders of magnitude improvementin terms of large scale preparation of 2D MXenes with controllable functionalisation and beyond. The success of this projectwill make a substantial contribution to one of the European Union main concerns on developing nanotechnologies andadvanced materials. Overall this proposed multidisciplinary project brings benefits to both the applicant and the hostinstitution (University of Manchester) in terms of  mutual knowledge transfer, joint publications, new collaborations