RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'On-line control of drawing and blanking process and quality of the product', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

In order to modernize their production tools, the blanking-drawing companies are trying to improve their productibility by maximizing the automation and the press integration of product control. This project aims to develop hybrid industrial control tools and methods leading to zero defect". These methods should be used during the drawing and cutting sequence either directly in real time under the press or in hidden time outside of the press, which would result inane instant diagnostic of each part either cut or drawn so as to control the production both unitise and globally. Wetmore specifically refer to two emerging methods: acoustic emission to directly control the products under the press, and computer-aided vision control. The project implies an association of the competencies of laboratories specialized in acoustics and vision, designers and manufacturers of industrial control equipment, and principally industrialists using be drawing and cutting process to validate and exploit the results and methods. The Exploratory Award which is of cooperative nature as it mainly associates small- and medium-size firms allows the implementation of a wide-spanning project meeting the CRAFT program objectives."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'A research strategy for developing systematic innovation tools for the food industry' (FOODINVENT), addressing dissemination and exploitation.

assistant: **Impact**

It is proposed to organise a Workshop that will bring together experts in systematic innovation & TRIZ, food researchers, and industrialists. The objective of the workshop is to analyse the potential of systematic innovation tools and approaches, such as TRIZ, semantic processing technologies, and knowledge processing systems for cost-effective innovation in the food industry . As the scientific systematisation of biological systems is still lacking, it is envisaged that research projects need to be organised to develop a food industry-oriented system. The major outcome of the workshop will be the strategy for setting up the research initiatives required.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'CLONAL AND CELLULAR HETEROGENEITY OF BREAST CANCER AND ITS DYNAMIC EVOLUTION WITH TREATMENT' in the context of a Horizon 2020 call.

assistant: **Objectives**

CLONAL AND CELLULAR HETEROGENEITY OF BREAST CANCER AND ITS DYNAMIC EVOLUTION WITH TREATMENTBreast cancer remains one of the leading causes of cancer death in women. One of the greatest challenges is that breast cancer is a heterogeneous group of 10 diseases defined by genomic profiling. In addition, each tumor is composed of clones and clonal evolution underpins the successive acquisition of the hallmarks of cancer, including metastasis and resistance to therapy. Furthermore tumors display biologically and clinically relevant cellular heterogeneity: immune system, vasculature, and stroma.  This cellular heterogeneity both shapes and is shaped by the malignant compartment and modulates response to therapy. This proposal will use longitudinal studies to unravel the clonal and cellular heterogeneity of breast cancer and its dynamic evolution with treatment. The overall goal is to provide a systems level view of evolving clonal and cellular architectures in space and time along the clinical continuum of breast cancers in the clinic, leading to the discovery of new biological and clinical paradigms which will transform our understanding of the disease. The overall approach is to capture the evolution of clonal and cellular heterogeneity of breast cancers in space and time using unique clinical cohorts where samples (biopsies and blood/plasma) are available spanning the whole disease continuum: early breast cancer surgically treated with curative intent, neo-adjuvant therapy, and matched relapse/metastasis. The 4 aims of the proposal are:1. Characterization of the clonal and cellular heterogeneity of primary tumours from the 10 genomic driver-based breast cancer subtypes (ICs)2. Comparative characterization of the clonal and cellular heterogeneity of matched pairs of primary
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'ROS-Industrial quality-assured robot software components' under Horizon 2020.

assistant: **Concept**

ROSIN will create a step change in the availability of high-quality intelligent robot software components for the Europeanindustry. This is achieved by building on the existing open-source “Robot Operating System” (ROS) framework andleveraging its worldwide community. ROS and its subsidiary ROS-Industrial (European side led by TU Delft andFraunhofer) is well-known, but its European industrial potential is underestimated. The two main critiques are (1) is thequality on par with industry, and (2) is there enough European industrial interest to justify investing in it? Partially, theanswer is “yes and yes”; ample industrial installations are already operational. Partially however, the two questions holdeach other in deadlock, because further quality improvement requires industrial investment and vice versa. ROSIN willresolve the deadlock and put Europe in a leading position.For software quality, ROSIN introduces a breakthrough innovation in automated code quality testing led by IT UniversityCopenhagen, complemented with a full palette of quality assurance measures including novel model-in-the-loop continuousintegration testing with ABB robots. Simultaneously, more ROS-Industrial tools and components will be created by making50% of the ROSIN budget available to collaborating European industrial users and developers for so-called FocusedTechnical Projects. ROSIN maximizes budget efficacy by alleviating yet another deadlock; experience shows that industrywill fund ROS-Industrial developments, but only after successful delivery. ROSIN provides pre-financing for developerswhich will be recovered into a future revolving fund to perpetuate the mechanism.Together with broad education activities (open for any EU party) led by Fachhochshule Aachen and community-buildingactivities le
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Production of bioactive glass ceramics by laser spinning of nano- and micro-fibres' under Sixth Framework.

assistant: **Concept**

A novel technique called laser spinning will be employed to synthesize glass ceramic fibres with several compositions and structures, showing diameters in the range from nanometres up to micrometers. This novel technique presents different advantages such as the simplicity of the experimental system which is carried out in ambient conditions and a high production rate, and also several potential possibilities such as the ability to produce fibres with different compositions and morphologies. All together s et this novel technique in a promising position to be applied to synthesize bioactive ceramic fibres with tailored properties in the nanometre and millimetre ranges.The general objectives of the project are: to study the laser spinning process and the grow th mechanism of the fibres, and to achieve the control of the composition and morphology of the fibres produced.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Quantum-Enhanced Optical Magnetometers' (QUTEMAG) under Horizon 2020.

assistant: **Objectives**

During the past ten years tools from Quantum Optics such as quantum-non-demolition (QND) measurements and squeezed light have emerged as powerful means to control quantum states of matter, perform ultra-sensitive measurements, and enhance physical systems beyond their classical limits.  At the same time optical magnetometers developed within the discipline of Atomic Physics have established themselves as the most sensitive detectors of magnetic fields with current performance reaching the limits of classical techniques. To date, in a proof-of-principle way, QND and squeezed light have been used to improve the performance of these instruments independently but not within the same device. Their simultaneous use in a best-in-class magnetometer remains an open challenge. To achieve this ambitious research goal we propose to combine QND and squeezed light resources to magnetometry at large atomic densities, i.e. in a regime where spin-exchange collisions dominate the spin dynamics. This novel approach will be key in enhancing current technology most suitable to address challenges in the real world. QUTEMAG combines a wealth of expertise in Optical Magnetometry and Quantum Optics. The Experienced Researcher Dr. Ricardo Jiménez Martínez, is an expert in Optical Magnetometry. The Supervisor Professor Morgan Mitchell is a leader in QND methods and quantum light pioneering the techniques that will enable the quantum-enhancement of optical magnetometers in the proposed work. The goal of the training program of the researcher is to develop new research competencies in quantum optics and managing skills of interdisciplinary research in Quantum Optics and Metrology, Atomic Physics and Photonics.The Host Institution, ICFO-The Institute of Photonic Sciences in Spain, provides a world-c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Intraepithelial gd (gamma delta)T cell receptor specificity' (IGDTCRS) targeting Sixth Framework.

assistant: **Abstract**

It has become clear that unconventional T cells, play a critical role in cellular immunology. Whilst much work is in progress concerning the molecular characteristics of such cells, and of their human counterparts, we remain conspicuously ignorant of t he cells' specificities.The work will be to apply a system that may identify the ligands of the TCR (T receptor) from the mouse skin and from the mouse and human gut. This work is a natural extension of previous projects in the lab that examined TCR biochemistry, that created critical reagents that the project will utilise (rat basophil leukaemia (RBL) transfected with TCR, recombinant soluble TCRs), further reagent (TCR-sensor system).Three experimental systems using these tools, will permit us to screen epithelial cell line expressing the specific ligand and to subject them to expression cloning. The success of these studies will dramatically improve our picture of tissue-surveillance, and the processes by which normal tissue homeostasis transforms into a situation in which the tissue-associated T cell repertoire becomes activated.The experience profile of Jean-Jacques Mention on IEL background, experiences with confocal microscopy, flow cytometrie can clearly add value to the applied project. He will be trained in advanced techniques in molecular biology like expression of soluble gdTCR.Thus the experience of Jean-Jacques Mention on the one hand and the training possibilities offered at the laboratory of Adrian Hayday on the other hand, are complementary. This will result in a synergistic effect and therefore enhance the scientific excellence of the European Union.The training and experience Jean-Jacques Mention will gain from his participation in the proposed project at the laboratory of Prof. Hayday in London, will c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Development of a low cost in-line polymer inspection system to improve the use of recycled materials in plastics processing industry' (POLYSENSE) under Seventh Framework.

assistant: **Objectives**

The polymer industry, including producers, converters and machine manufacturers employ 1.6 million people and generate annual sales worth over €300 billion. Europe is the world leader in plastics recycling and the second worldwide plastic producer, but competence by emerging industrialised nations, such as China, is growing bigger and represents a major thread for European interests in mid and long term. There is recently a big concern towards the recycling of wasted materials, including plastics. Despite the growth of recycled materials in the polymer sector, there are presently two main factors that prevent a higher use of recycled materials: Uncertainty in fixing final product density and quality of the final product, which is directly affected by viscosity of the blend. Yet despite this tremendous competition, many polymer processes still rely on trial and error for their optimisation, leading to the creation of enormous tonnes of scrap during adjusting periods. Current methods, which enable only indirect measurements such as temperature, screw torque and pressure, prove completely insufficient for characterising such complex behaviour. The industry needs rapid, reliable, non-invasive and cost effective analytical methods for process control in order to ensure desired values of density and viscosity of the polymer. This project thus proposes to develop a compact, non invasive, real-time sensor based on an ultrasonic piezoelectric transducer for in-line measurements during polymer processes. POLYSENSE will be designed for suitable insertion in a standard pressure port, which will enable the in-line measurement of density and viscosity of the polymers while circulating in a molten state inside the machine allowing the prediction of the polymer behaviour and the feedba
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Peptide Sensing Platforms for proteins and antibodies detection' under Seventh Framework.

assistant: **Concept**

The present fellowship proposal aims to give the applicant a strong expertise in peptide folding and peptide based sensors. This objective will be reached through a scientific project focused on the development and optimization of a novel, rapid, point-of-care method for the simultaneous detection of multiple diagnostic proteins. The approach, which will utilize electrochemistry to monitor the binding-induced folding of peptide/polypeptide used as recognition elements, will be rapid, specific, convenient and, critically, selective enough to be employed directly in blood serum and -we propose- whole blood.Through a multidisciplinary and complementary approach the fellow will be trained in protein and peptide folding, a field fundamental to develop the proposed biosensor platform. Training on peptide labeling with redox tags and on formation of peptide films on different sensor surfaces will be also exploited during the fellowship in order to achieve the final research objectives. Outgoing and return host institutions have both the required expertise for these training and scientific objectives. In particular, the outgoing host, Prof. Plaxco lab at UCSB, USA, has a unique strong expertise on both peptide/protein folding and electrochemical sensors. The outcome of the fellowship will be crucial for the applicant’s future career and will not only strengthen his scientific knowledge but also his communication and didactic know-how. Moreover, the peptide sensors developed could be of strong impact for the scientific excellence of European Community.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Development of a hot electron bolometer for sub-mm and x-ray spectroscopy applications', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Research objectives and content Since about one year SRON has started a new, very promising development line on Hot Electron Bolometers. When operated in extreme electrothermal feedback these detectors outperform the standard microcalorimeters both in respons speed and limiting energy resolution. The objective of the proposed project is the development of these detectors for two potential applications: 1. Sub-mm detection of the cosmic microwave background onboard ESA's Cobras/Samba satellite. At present this instrument is equipped with standard bolometers. Implementation of the hot electron bolometers would improve on the detection accuracy. Discussions have started with the principal investigator of the instrument. 2. Imaging X-ray spectroscopy with a high detection efficiency in the 0.5 - 15 keV energy range on board of a future ESA or NASA X-ray Spectroscopy satellite. The aim is to develop a 100 times 100 array of Hot Electron bolometer elements, each with a spectral resolution of about 5 eV for 6 keV X-rays. Training content (objective, benefit and expected impact) I have been working with radiation detectors for about 7 years, mainly gas detectors, and I think there are very new techniques in this field that have very promising applications. The superconductors radiation detectors have excellent performances like energy resolution which allow further steps in fields like astronomy, environment studies, material analysis, etc. There are good perspectives of Portugal joining ESA so, within this context, space applications will be a good field to be involved in, because new perspectives will appear for portuguese researchers. I also think that for someone living in a country where the scientific equipment resources are very limited it is verM important to work in an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'European multiple system atrophy study group' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Multiple system atrophy (MSA) is a progressive neurodegenerative disorder, which frequently presents with the features of Parkinson's Disease, but in contrast to latter, causes early death and prolonged severe disability. The proposed concerted action will pave the way towards neuroprotective intervention trials in MSA by developing a trial protocol 'CAPIT-MSA) and by implementing a central MSA Registry (EMSA-R) for centralized data acquisition during a multicoated natural history study that will enable us to define rates of disease progression and to validate the CAPIT-MSA protocol. Furthermore, candidate neuroprotective agents will be screened in proof of concept studies using an established animal model of striatonigral degeneration. Pending ongoing preclinical safety and phase I studies of these agents by the industrial partners, one of the agents will be selected foray multicoated safety and tolerability phase II trial commencing at month 18.