RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Integrated Modular Energy Systems and Local Flexibility Trading for Neural Energy Islands'.

assistant: **Objectives**

The de-centralization of electricity generation requires equally de-centralized and affordable solutions to integrate more RES, increase the security of supply and decarbonize the EU energy future. The combination and unique integration of de-centralized storage with technologies for local energy system optimization, including demand response, electric vehicle charging optimization and synergies with other energy vectors at the local level, can offer a cost-efficient pathway (in comparison to high-CAPEX grid upgrade investments) for local energy systems optimization in presence of high volumes of volatile and intermittent RES, since huge amounts of currently non-utilized flexibility can be unleashed to ensure optimal congestion management and effective tackling of local instabilities and imbalances. MERLON introduces an Integrated Modular Local Energy Management Framework for the Holistic Operational Optimization of Local Energy Systems in presence of high shares of volatile distributed RES. Optimization in MERLON applies to multiple levels spanning optimal coordination of local generation, with demand and storage flexibility, as well as flexibility offered by EVs and CHP Plants to facilitate maximum RES integration, avoidance of curtailment and satisfaction of balancing/ ancillary grid needs. MERLON will enable the realization of novel business models, allowing local energy communities to introduce themselves in local flexibility markets, while paving the way for the realization of novel Microgrid-as-a-Service models, assigning to local DSOs the role of “Aggregator of Aggregators” for the provision of added value services to the overlay distribution grid.  It equips local stakeholders (DSOs, energy cooperatives, prosumers) with innovative and highly effective tools for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Development of CO2 transport and storage demo project in Eastern Europe - Eastern Lights' to be submitted under Horizon Europe.

assistant: **Abstract**

Eastern Lights (EL) is the de-risking first step to develop a large-scale CCUS cluster in Eastern Europe. The Holcim Bulgaria plant will be the heart and engine of the cluster development starting with CO2 transport and storage (T&S) demonstration in North West Bulgaria. EL will de-risk the CO2 transport and storage by eliminating the main uncertainties of T&S by industrial demonstration, in-depth studies and stakeholder engagement. By constructing and testing a km long transport pipeline fully integrated into the commercial operating CO2 storage, the key process parameters and technical aspects for a full-scale CCUS complex will be validated. The critical risks of the T&S part will be eliminated by an industrial demonstration and comprehensive set of studies leading to permitting.To minimize the risks, saline aquifers from North West Bulgaria will be used for safe and large capacity CO2 storage close to a major CO2 source and Bulgarian pipeline corridors. Extensive geological, geophysical and testing work will be done to address critical issues as induced seismicity and safe injection over time. By actually constructing a short pipeline, specific issues like land-owner allowances will be addressed and the transport will be made ready for permitting and execution for the entire corridor cross-border cluster connecting members to the CO2 sink. Intensive communication, stakeholder consultation, cluster development and permit preparations will complete the Eastern Lights scope. As such, Eastern Lights shall unlock the CCUS potential in Eastern Europe, Bulgaria in particular and potentially Romania, therewith contributing to the Fit for 55 targets. Demonstrating an economically feasible decarbonizing track for the (cement) industry in Bulgaria, will secure jobs and economic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Rewiring with biased signaling to override oxidative pathway defects for SEPN1-related myopathy therapy', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

SEPN1-related myopathy (SEPN1-RM) is a rare, untreatable debilitating congenital myopathy in which SEPN1 mutations impair the antioxidant system, ER stress protection and mitochondrial oxidative function.  These altered cellular processes ultimately lead to a significant loss of bioenergetic production and abrogate muscle cellular functions. SEPN1-RM patients experience potentially-lethal respiratory failure and major life burden due to loss of mobility. Currently, there are no high-throughput or appropriate preclinical models to facilitate identification of disease-modifying drugs; this has hampered efforts in devising therapeutic strategies. To overcome these bottlenecks, I aim to use patient-derived cells to establish (1) high-throughput measureable readouts of metabolism, facilitating repurposed drug screen for SEPN1-RM; (2) an original treatment strategy by exploiting potential biased signalings, which bypass SEPN1 defects to restore cellular bioenergetics.  I will capitalize on (1) the availability of SEPN1-RM biopsies, (2) host lab expertise for handling and culturing primary SEPN1-RM cells and (3) my experience in muscle biology and innovative tools for analysing metabolic/signalling pathways.  I aim to implement transcriptomic analyses by using next-generation RNA-seq, optogenetic based sensors to quantify metabolic activity, real-time clonal analysis of cell fate with dynamic fluorescent time-lapse microscopy and multi-dimensional assessment of intracellular activities at single-cell level via CYTOF technology.  This study will not only facilitate the establishment of SEPN1-RM biomarkers and novel therapeutic studies, it will also provide a model paradigm for analysing and treating other inherited or acquired myopathies sharing an underlying bioenergetic defic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Socio-Semantic Bubbles of Internet Communities' (SOCSEMICS).

assistant: **Concept**

SOCSEMICS aims at developing a set of integrated, groundbreaking methods to address the possible existence of so-called “filter bubbles” in the digital public space. In all generality, this phenomenon may be construed as communities whose actors are more or less prone to interaction and open to informations coming from “outside” of these communities. SOCSEMICS will contribute to the formalization and operationalization of this question by addressing three current challenges: (i) developing a comprehensive theory of reinforcing and self-sustaining socio-semantic communities by appraising the social, semantic and socio-semantic realms simultaneously, (ii) drastically improving content analysis by replacing classical distributional approaches with clause analysis, and thereby enabling quantitative analyses which render the linguistic complexity of utterances in web corpuses, (iii) fostering the interface between these methods and qualitative approaches, especially through a couple of broad case studies, together with the development of interactive platforms implementing the above innovations and facilitating digital social research.


**Keywords:** filter bubbles,  socio-semantic networks,  digital public space,  content and clause analysis,  online conversation spaces ,  socio-semantic visualization
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Optimizing delivery of health care interventions' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

ODHIN is a Europe wide project involving research institutions from nine European countries that will help to optimize the delivery of health care interventions by understanding how better to translate the results of clinical research into every day practice. ODHIN will use the implementation of identification and brief intervention (IBI) programmes for hazardous and harmful alcohol consumption (HHAC) in primary health care (PHC) as a case study. There is strong evidence for the effectiveness and cost-effectiveness of IBI in reducing HHAC and its consequences, which include more than 60 clinical diagnoses and conditions. A series of systematic reviews investigating the impact of different behavioural, organizational and financial strategies in changing provider behaviour across a range of clinical lifestyle interventions will be undertaken. The knowledge base of potential barriers and facilitators to implementing IBI will be updated. A stepped cluster randomised controlled trial will be undertaken with five arms and three time phases to test the incremental effect of strategies. Phase A will aim at raising awareness, insight, and acceptance of performance of IBI in PHC. Phases B and C will aim at acceptance, change and maintenance of implementation with financial and organisational strategies used in a different order to test the impact of both separately and in sequence. Modelling studies will test the impact of different IBI approaches on changes in alcohol consumption and the resulting impacts on healthcare costs and health-related quality of life. ODHIN will build a clinical evidence-based database on effective and cost-effective IBI measures for use in PHC and will develop a tool to assess the extent of provision of clinical practice. A project website and a series
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'SOciO-eConomiC failurE and aSpiration biaseS' in the context of a Horizon 2020 call.

assistant: **Objectives**

From early childhood, many poor children brought up in segregated communities observe socio-economic failures such as poor living conditions, liquidity constraints, extremely high unemployment and low education levels attained by adults. Enhancing their aspirations is believed to be a tool capable of breaking one of the poverty feedback loops: poverty has been identified as a cause of the failure to aspire to one’s own potential, and at the same time, low aspirations are among the potential causes of persistent poverty. Consequently, adolescents from areas of high deprivation are generally believed to have low aspirations, though, in fact, their aspirations vary considerably, and may be generally high. This signals two main aspiration biases: aspirations failure and aspirational gap. This project is aimed to investigate how stimulating success/failure environments can reduce aspiration biases of the segregated poor, which, according to theory, should increase their chances to escape the poverty trap. The project has an interdisciplinary character: it is aimed to investigate the psychological construct of aspirations in the economic context in educational environments. Using cutting-edge methods from behavioural and experimental economics, we will experimentally investigate to what extent exposure to success/failure environments will lead to a significant decrease/increase in aspirational biases. From the methodological perspective, we will first design a novel approach to the experimental elicitation of aspirations, then we will design an experiment manipulating success/failure to assess their effects on aspirations. From the empirical viewpoint, using experimental data, the project will shed new light on the relationship between socio-economic background and aspiration
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Single molecule dynamics of stress signalling components studied with the ulta-sensitive fluorescence microscope Cytoscout for drug screening' (SIMODSS), addressing dissemination and exploitation.

assistant: **Impact**

This project focuses on the elucidation of membranes as targets of stress signalling. Stress signalling plays a crucial role in chronic disorders like diabetes mellitus, heart disease, kidney failure or neuro-degenerative disorders. We will improve the understanding of the molecular basis of the diseases by applying a new imaging technology to study the membrane dynamic processes. The new technique permits the visualisation of single molecules and will be applied to investigate the level and cellular localisation of e.g heat shock proteins and to observe lipid- and protein-specific membrane domains and rafts engaged in HSP-signalling. An immediate outcome of the proposed research will be a better understanding of the molecular basis of the membrane-associated diseases. We also expect that the project will lead to the identification and characterization of new drug compounds, which rebalance the perturbed levels of HSP proteins in diseased tissue. Through the proposed project the host institutions Upper Austrian Research GmbH (UAR) and the Biological Research Center, Hungarian Academy of Sciences (BRC) will intensify their ongoing collaboration and combine their scientific strengths to improve the understanding of molecular basis of membrane-associated diseases. BRC is one of the leading scientific institutions working on stress-signalling of membranes and their involvement in diseases. UAR is a leading company in developing ultra sensitive fluorescence microscopes for single dye tracing (SDT) and HTS with single molecule sensitivity used for life science applications. The trade name of this tool is CytoScout. This integrated project follows a multidisciplinary approach and brings together experts from physics, chemistry, biology, molecular biology, clinical diagnostics,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Flowbase' under Horizon 2020.

assistant: **Concept**

Miraminds currently offers software which enables IT-divisions of SMEs to automatically capture and store workflows for their colleagues. The next step is to develop a solution for this final and most challenging problem: automatically displaying the right workflow upon need of the user, without the user searching for it himself. Solutions that are similar to miraminds are only affordable for medium and large size companies. They have a long implementation period and require a great effort of all employees involved.The objective of the recruitment of the innovation associate is developing a technology that replaces the cumbersome manual loading of files from a local file system with an intelligent (AI-based) cloud solution (named Flowbase) that allows for:- Automated and seamless storing/loading of workflow data on a server/cloud from within our desktop software product.- Intelligent search and/or recommendation of workflows based on a user’s work context.By offering this new solution (Flowbase) we are planning to transform miraminds from a pure software vendor toward a data/platform/AI company. We offer the opportunity to introduce machine learning expertise into a new area of application which will possibly come with unique challenges and thus, lead to unique research results. To task of the associate will be to utilize predictive analysis with an approach that in the literature is known as collaborative filtering.The intelligent platform Flowbase would offer IT departments in SMEs an affordable and easy to use solution to automate and individualize their first level IT support.


**Keywords:** developing a technology that replaces the cumbersome manual loading of files from a local file system with an intelligent (AI-based) cloud solution
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'The role of the tumour metastasis gene tiam1 in cell signalling and development'.

assistant: **Objectives**

Research objectives and content The tumor metastasis gene Tiaml was identified through retroviral mutagenesis of T-lymphoma cells followed by screening for invasive phenotypes. This gene encodes a guanine nucleotide exchange factor for the Rho-family small GTPase Rac demonstrating a role for the Rho-family in tumor invasion and metastasis. The normal, non-oncogenic cellular context of Tiaml signalling through Rac has yet to be defined, although Tiaml expression in specific regions of the brain suggests roles in neuronal migration and maturation. Since preliminary data suggests that interacting proteins regulate Tiaml activity we will characterize partners for Tiaml through protein interaction assays. At the same time we will develop transgenic models to elucidate the role of Tiaml in brain tissue development through conditional expression of wildtype, constitutively active and dominant negative Tiaml mutants. This project will improve our understanding of Tiaml function in development and in cancer metastasis. It will demonstrate the utility of emerging techniques applied to investigate this important family of oncogenes. Training content (objective, benefit and expected impact) The training will familiarize me with contemporary techniques in cell biology and give me specialized knowledge in development of transgenic mice and their subsequent analysis. These are techniques which will complement my present expertise in molecular biology.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Marketing Conservation Services - a European Manual' (2007-2013).

assistant: **Concept**

In spite of the supragenerational importance of the conservation services aiming to preserve the cultural heritage in the best possible way, one can observe that the communication between the providers and prospective beneficiaries of these services is rather imperfect. It is also observed that few actions aiming to raise the social awareness of the need for appropriate preservation of cultural heritage and - consequently - the public interest in and demand for conservation services. The negative results of these communication failures can be compensated if appropriate marketing tools be introduced that aim to eventually enhance the commercial accomplishments of a conservation service provider and – primarily – to raise the social awareness of how the cultural heritage should be appropriately taken care of. In her initial Marie Curie research, the Researcher carried out an empirical analysis of the Maltese conservation market, including an extensive analysis of the demand and the supply side, in order to provide basis for constructing theory in the novel field of marketing conservation services that would help to identify set of principles applicable by conservators in their professional practice, in particular in their communication with both, prospective and existing customers and with the general public. In view of the above and following the objectives set in her initial Marie Curie Fellowship, the Researcher aims to verify in this reintegration project the applicability of the previous findings in the wide European context. Having done that, she aims to draw up a handbook in marketing that would contain knowledge about the marketing mechanisms pertaining specifically to the conservation services. Such handbook would become a practical tool to be used by European co