RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Tracking the spread of avian influenza viruses in live bird market networks'.

assistant: **Objectives**

Avian influenza viruses (AIV) represent tenacious and major public and animal health problems across the world. Controlling AIV at its poultry source in Asia is essential to decrease the virus load in susceptible avian species and environment, limit the risk of human infection with AIV and minimize the risk for future global AIV pandemics. In TrackFLU, I will improve our capacity to quantify, model and predict the AIV spread in live bird market (LBM) networks in Asia, which are urgently needed if the impact of future epidemics of AIV is to be mitigated and thus, represent key elements for pandemic preparedness. For the first time, extensive field work will be combined with state-of-the-art network analysis, phylodynamic and disease modelling tools with the view to successfully influence policy-making. I will use this unique and innovative analytical pipeline to address the following key objectives: O1) Identify the factors shaping the connectivity of LBM networks, O2) Quantify the transmission dynamics of AIV in LBM networks and O3) Optimize strategies to limit AIV spread in LBM networks. TrackFLU will help us to disentangle the LBM networks connectivity and to resolve the AIV transmission dynamics in LBM networks. TrackFLU will result in a cutting-edge predictive model of AIV spread that incorporates, for the first time, most of the biological complexities of AIV spread in LBM networks in Asia. The model and its associated web-application will represent very powerful and innovative tools for the design of novel control strategies tailored to the key features of AIV transmission in LBM networks. TrackFLU will thus contribute to the active research issue of improving capacity to predict AIV transmission in these complex systems in Asia, hence addressing the unmet need of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Genomics and Personalized Medicine for all though Artificial Intelligence in Haematological Diseases' to be submitted under Horizon 2020.

assistant: **Abstract**

GENOMED4ALL will support the pooling of genomic, clinical data and other “-omics” health data (data EHR,  PET, MRI and CT , Next Generation Sequencing, Microarray, Genome Wide Association, Copy Number Variations, DNA sequencing, RNA sequencing, including single cell, etc.) through a secure and privacy respectful data sharing platform based on the novel Federated Learning scheme, to advance research in personalised medicine in haematological diseases thanks to advanced novel AI models and standardized sharing of cross-border data. GENOMED4ALL will make use of the existing infrastructures and initiatives, including powerful High Performance Computing facilities, hospital registries, data processing tools, and pre-existing repositories, starting from 10 clinical partners repositories to be enlarged especially by the resources provided by ERN-EuroBloodNet where GENOMED4ALL clinical partners have a leading position, which contain 66 relevant clinical sites providing repositories and knowledge,  for the successful exploitation of genomics, clinical and other related “-omics” data to facilitate personalised medicine in common, rare and ultrarare haematological diseases to demonstrate the versatility and utility of the solutions, and 20 external of this network.GENOMED4ALL will demonstrate the potential and benefits of trustable and explainable AI technologies, with a novel approach to AI models and algorithms using AI advanced deep learning, variational autoencoders, generative models, besides combining with advanced statistical and Machine learning processes approaches to exploit the powerful set of “-omics” data which will be at researchers’ disposal. This will allow for identifying new knowledge, to support clinical research and decision making by linking Europe's relevant
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'FULLY INTEGRATED ENERGY SYSTEM FOR HIGHER EFFICIENCY WASTE UTILIZATION AT A CHIPBOARD FACTORY' (1994-1998).

assistant: **Concept**

The main aim of the project is to increase energy efficiency in the chipboard production process by enhancing the useful value of the wood waste through its conversion in electricity. The Integrated Energy System has been designed in such a way that, complemented with a new top cycle combined heat and power application, a yearly primary energy saving of 19.594 toe can be achieved what will lead to a cut of the energy cost by 100% and obtaining a net income (excluding operating and maintenance costs) of 630 MESP mainly due to the exported power while improving the environment and increasing product quality and energy supply reliability. A proper performance of the whole system should be demonstrated. In this subject a high efficiency and availability of the heat recovery system must be reached, even taking into account the extremely difficult conditions of the flue gases. The scheme will also improve the environment by lowering the CO2 emissions by 82100 tons per year.The Design, Manufacture and Assembly/Installation/Erection phases of the project have been fully completed and most of commissioning. The monitoring phase is ready to start.The Dryers operating with hot gases from the Turbine have been put into service in an optimum fashion, and operating control of the Dryers themselves has presented no problem whatsoever. Likewise, an improvement has been observed both in the quality of the product upon elimination of the impunities in the gases that were accumulating on the boards and in the operational availability of the plant.Taking full advantage of the surplus heat of the Gas Turbine gases not used in the Dryers has proven somewhat difficult at times of operation when the demand of the dryers is such that the large gas bypass valve that regulates pressure in the duc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Water Scarcity as Potential Cause of Global Conflict – Time for UN Green Helmets or a New EU Water Strategy?' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The suggested study aims to examine the relationship between water scarcity and armed conflict, and to develop legal and policy recommendations for the UN and the EU to counteract water scarcity as a potential driving force of armed conflict.Firstly, the study will identify to what extent greater water scarcity as a result of climate change constitutes a threat to peace and security. By analysing empirical data, and by conducting three case studies, the study will answer the question of how best to re-conceptualize the general connection between both water scarcity and armed conflict.Secondly, the study will address the question of how the UN should best tackle this connection. Suggestions within the UN system include the involvement of the Security Council, the appointment of a UN Special Rapporteur on the issue of climate change and international security, and the reform of existing international processes in the United Nations Framework Convention on Climate Change (UNFCCC) as the key actor to negotiate climate change targets.Thirdly, the study will evaluate which policy the EU, with its tradition of promoting peaceful co-operation amongst nations, should develop on the issue of water scarcity and armed conflict in its external relations, in particular how should it reshape structures and processes for future negotiations with EU candidate countries, such as Turkey, which have significant disputes over water with their non-European neighbours (e.g. Syria and Iraq)?Adressing the topics of climate change and armed conflict through a multi-disciplinary lense, the project, and its underlying topic, is of significant societal and academic relevance, and at the same time of utmost importance for the maintenance of international peace through the UN and the EU.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'A therapeutic software that delivers remote speech therapy to individuals with Parkinson's disease' under Horizon Europe.

assistant: **Concept**

Parkinson’s disease (PD) is the second most common neurological disease worldwide after Alzheimer’s and is the fastest growing one. Over 10 million people in the world are living with this disease, of which about 90% will experience difficulties with their voice as the disease progresses.At Teleatherapy, our goal is to make speech and language therapy accessible to all patients with Parkinson’s disease and to improve the service provided by speech and language therapy clinics. Our Teleatherapy platform aims to do this by allowing patients to practice therapy at home. Patient monitored through the platform enables therapists to receive key insights, saving therapists time and ensuring patients get the early intervention they require.Teleatherapy is a web-based care management platform allowing therapists to: customize care plans for patients; monitor their progress by assessing the strength of the individuals' voice; and provide feedback each time the patient practices and adjust care accordingly. In parallel, it allows clinics to: increase their caseload; personalize speech therapy plans; and maximise patient compliance by allowing them to practice speech therapy on our mobile app. This will contribute to a significant reduction in PD treatment costs for the healthcare systems and wait lists.PD Patients download a mobile app which delivers their care programme, analyses their voice, and tracks their progress for their therapist. Patients are guided through their practice with exercises, i.e. volume exercises, high and low pitch exercises, and practicing key every day phrases. Planned improvements to our Software as a Service will include the use of machine learning algorithms supporting enhanced voice analysis and progress monitoring, and the implementation of decision
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'BIO-MICRO: Biomarkers and Intervention Outcomes in Micronutrient Optimization' (BIO-MICRO) under Horizon Europe.

assistant: **Objectives**

European micronutrient (MN) guidelines explicitly recommend to replete any MN deficiency in critically ill patients. MNs are crucial for immune defence, cellular metabolism and as antioxidant. Critically ill patients have increased requirements for MNs which can result in severe deficiencies and worse clinical outcomes. There are currently no accurate methods to diagnose MN deficiencies in critically ill patients. MN plasma concentrations are substantially affected by inflammation. MN concentrations in erythrocytes and leukocytes or new functional markers may better reflect real deficiencies. Furthermore, most intervention trials with high-dose MN monotherapy yielded mixed results on clinical outcomes. Due to the absence of accurate monitoring tools of MN body status, all patients received fixed high-dose MN monotherapy. Personalized MN therapy based on subphenotyping of patients and accurate estimation of individual metabolic demands in all phases of disease may yield better outcome than this one-size-fits-all strategy. In addition, more insight in the complex interplay between MNs and the role of MNs in post-ICU phase is necessary to guide future trials. BIO-MICRO consists of physicians, biologists, methodologists, trialists, health scientists, clinical chemists, patient representatives and industrial participants and aims to train innovative research fellows with interdisciplinary and intersectoral skills to develop the urgently needed strategies for MN personalized therapy in critically ill patients. They will develop new analytics for reliably determination MN body status, investigate subphenotypes of patients likely to benefit from MN therapy, enable guidance with appropriate timing of MN therapy, investigate the interplay between MNs and explore the role of MNs i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Ultrafast dynamics of hydrogen bonded structures in condensed matter' (ULTRADYNE), addressing dissemination and exploitation.

assistant: **Impact**

Structure-function relationships in condensed matter will be unraveled by studying structural dynamics on atomic length and time scales. The most advanced structure-sensitive methods of ultrafast science such as time-resolved x-ray diffraction and multidimensional vibrational spectroscopy with a temporal resolution better than 100 fs will be applied for mapping fluctuating (macro)molecular structures and photoinduced structural transformations of solids in real-time. The following phenomena will be addressed: (i) Interactions between functional units of individual nucleic base pairs and deoxyribonucleic acid (DNA) oligomers will be determined by multidimensional vibrational spectroscopy. The transfer of excitations in a local geometry and along the double helix, energy dissipation along the helix and into the aqueous environment, as well as the mechanisms of local and global hydration will be studied via the ultrafast response of local vibrations. In this way, hydrogen bonding interactions of water with the DNA backbone and with base pairs are discerned. (ii) Photoinduced structural transformations in prototype hydrogen-bonded solids will be studied by ultrafast x-ray diffraction. The so far unknown dynamics and driving forces of phase transitions in molecular ferroelectrics such as ammonium sulfate and others will be determined by recording transient diffraction patterns after electronic and/or vibrational excitation. A key issue will be the so far unresolved change of the hydrogen bond pattern. This work will include the implementation of new forefront techniques of ultrafast science, e.g., ultrafast x-ray powder diffraction, for a broad range of future applications.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Investigating the neural correlates of working memory capacity using functional magnetic resonance imaging and transcranial magnetic stimulation'.

assistant: **Innovation**

The proposed research focuses on the neural substrates of human working memory (WM) i.e., the processes enabling the brief retention and manipulation of information when it is no longer present in the environment towards attaining behavioural goals. There is evidence that the prefrontal cortex (PFC) may be involved in controlling what is to be retained in WM, and that storage occurs in connected but distant brain regions i.e., in posterior cortex. Thus, the PFC may be the source of “top down” influences in WM. Furthermore, differences across individuals in the amount of information they can store (i.e., memory capacity) may depend, in part, on what is being stored, rather than the amount. Such individual capacity differences are reflected by differences in neural activity in storage-related brain regions. The proposed series of experiments aims to exploit these capacity-related differences in neural activity in order to provide causal evidence that (1) the retention of object-based information occurs in posterior cortex; (2) the PFC is functionally connected to these posterior storage regions and is the source of encoding signals directing what is to be stored; (3) differences in memory capacity across individuals is due, at least in part, to whether not relevant or irrelevant information is stored; (4) modulation of prefrontal encoding signals will result in changes in the both capacity-related neural activity in posterior storage regions, and in the psychological measures of individuals’ memory capacity. These aims will be explored using the cutting-edge combinations of both functional magnetic resonance (fMRI)-guided transcranial magnetic stimulation (TMS) and concurrent TMS-fMRI. The ability of fMRI to visual whole-brain activity during a task in combination with th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Universality Phenomena in Geometry and Dynamics of Moduli spaces' under Horizon Europe.

assistant: **Concept**

Geometry and dynamics in the moduli spaces proved to be extremely efficient in the study of surface foliations, billiards in polygons and in mathematical models of statistical and solid state physics like Ehrenfest billiards or Novikov's problem on electron transport. Ideas of study of surface dynamics through geometry of moduli spaces originate in works of Thurston, Masur and Veech. The area is flourishing ever since. Contributions of Avila, Eskin, McMullen, Mirzakhani, Kontsevich, Okounkov, Yoccoz, to mention only Fields Medal and Breakthrough Prize winners, made geometry and dynamics in the moduli spaces one of the most active areas of modern mathematics. Moduli spaces of Riemann surfaces and related moduli spaces of Abelian differentials are parametrized by a genus g of the surface. Considering all associated hyperbolic (respectively flat) metrics at once, one observes more and more sophisticated diversity of geometric properties when genus grows. However, most of metrics, on the contrary, progressively share certain similarity. Here the notion of most of has explicit quantitative meaning, for example, in terms of the Weil-Petersson measure. Global characteristics of the moduli spaces, like Weil-Petersson and Masur-Veech volumes, Siegel-Veech constants, intersection numbers of -classes were traditionally studied through algebra-geometric tools, where all formulae are exact, but difficult to manipulate in large genus. Most of these quantities admit simple uniform large genus approximate asymptotic formulae. The project aims to study large genus asymptotic geometry and dynamics of moduli spaces and of related objects from probabilistic and asymptotic perspectives. This will provide important applications to enumerative geometry, combinatorics and dynamics, including c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Pulmonary delivery of anticancer drug via an inhaled responsive nanogel with stealth ability and high targetability' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

In this project, I will investigate and develop nanogels incorporated into microgels containing encapsulated anticancer drugs. These nanogels will be delivered via the respiratory system to the lung, selectively swell and deliberate the therapeutic. Importance will be given to targeting moieties, stealth moieties, and biocompatibility. The delivery of drugs for lung cancer is limited but is under investigation and on the rise of inquiry. Some of the challenges this type of technology faces are the efficient encapsulation of the bioactive compound inside a nanocarrier, the targeted delivery, the release of the drug, the biocompatibility with the lung, and the avoidance of the macrophages. New methodologies for better delivery of therapeutics are of great importance at the National and International levels. New materials and technologies are emerging every year. The delivery of therapeutics for lung cancer is based mainly on intravenous therapies. Another way of introducing drugs into the area of importance in the lung could be pulmonary drug delivery as a good alternative. Pulmonary delivery is not a new technology but is strictly limited to specific conditions/illnesses. The research capitalizes on the existing strengths of the experienced researcher (ER) in polymer science and the expertise of the host institute in chemical biology in health, drug research, and biotechnology. It will lead to several publications in high-impact factor journals, transfer of knowledge and expertise that could be capitalized at an industrial level, thus contributing to the research output, distinctness, and economy of Europe. Overall, the fellowship will allow the ER to reintegrate into a long-term academic position after many years of fruitful research career in the academic sector in Spa