RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'high REsolution Spectroscopy for Process AnalytiCs' under Horizon 2020.

assistant: **Concept**

Online process monitoring in chemical production processes is critical to achieve high production yields resulting in high resource efficiency and is also an important cost driver in production environments, such as petrochemical refineries. Specifically chromatography is often used due to its selectivity, but the instruments require controlled environments and so-called shelters have to be built in refineries to house them and process streams also have to be re-routed to those shelters for on-line monitoring.The project RESPAC will prove feasibility of a broadband laser spectroscopy method in the mid-infrared for online process monitoring of complex mixtures by introducing a new mode of operation. The spectroscopy method is called “dual-comb spectroscopy”, which has been successfully used for laboratory analysis, but current implementations either lack selectivity (near IR combs) or spectral resolution (Quantum Cascade Laser mid IR combs) or integration level (near IR to mid IR converted combs), preventing them from industrial use.The method is called “rapid-sweep” for Quantum Cascade Laser mid IR combs and is a result of the H2020 flagship project “Qombs”, where the method has been discovered and consists in a rapid sweep of the broadband laser over the empty space between laser lines to achieve the complete spectral information required for distinguishing multiple gas-phase species.The project will include a proof-of-concept measurement, raising interest with end-users and efforts to partner with a current supplier of process analytical instrumentation for market entry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Photoexcitation Dynamics and Direct Monitoring of Photovoltaic Processes of Solid-State Hybrid Organic-Inorganic Perovskite Solar Cells' in the context of a Horizon 2020 call.

assistant: **Objectives**

Abundant, cheap and clean source of energy is fundamental to preserve global environment and sustained economic growth. Solar energy is considered as the ultimate solution in this regard. Among the three generations of solar cells developed with this objective, hybrid organic-inorganic perovskite solar cells with demonstrated power conversion efficiency (PCE) of over 22 % have bagged the greatest attention. Despite the impressive PCE, lower cost and facile processing opportunities for hybrid perovskite solar cells,  their commercialization is not yet realized; poor stability, lack of robustness to subtle variations in processing, and Pb toxicity being the bottlenecks. We take up the view that pursuing fundamental understanding of the photophysics and photovoltaic process of these highly  efficient  lead halide  perovskites can contribute to tackle their instability issue and also to the development of Pb free organic-inorganic halide perovskites with analogous optical and photovoltaic performance to that of former, expediting their market entry. Apart from photovoltaic sector, the fundamental knowledge evolved through this project is expected to have direct impact on the fabrication of high performing photodetectors, lasers, and light emitting devices based on hybrid perovskite materials. This interdisciplinary project lying at the interface of material science, physics and chemistry is expected to bring a breakthrough in perovskite solar cell research arena.The proposed project will utilize the applicant’s expertise in the fabrication of high efficient organic and perovskite solar cells in combination with world leading scientist Prof. Ifor Samuel’s expertise on photophysics aspects of thin film solar cells and the excellent infrastructure facilities at the host instit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Blood Biomarker-based Diagnostic Tools for Early Stage Alzheimer’s Disease' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Alzheimer’s disease (AD) affects more than 7 million people in Europe and this figure is expected to double every 20 years. Despite intensive efforts, no disease-modifying treatments or preventive strategies are available. The lack of specific, sensitive and minimally invasive diagnostics to identify people with early-stage AD to be included in clinical drug intervention trials is among the main reasons for many notable trial failures. The main challenges in developing the required diagnostics are identification of AD biomarkers and development of their detection techniques. The complex and interdisciplinary nature of the research underlines the need for innovative training of a new generation of researchers in the field. BBDiag responds to such a need and establishes a much-needed ETN for blood based early-AD diagnostics to address these challenges. It brings together leading academic and industrial experts from five major consortia in Europe and uses their synergies to build a triple-i research & training platform with the required multidisciplinary expertise and cutting-edge technologies. BBDiag Fellows will be trained under the Vitae Researcher Development Framework innovatively combined with the BBDiag platform for gaining interdisciplinary scientific and transferable skills as well as personal quality, creative thinking and business mind-set. The ETN has a highly innovative research programme for the discovery of AD biomarkers, development of novel biosensing techniques and point of care tools, and for technological exploitation of the diagnostics. These advances will strongly support improved care provision and development of disease-modifying treatments and preventive strategies for AD patients. More importantly, BBDiag will deliver its first generation of 13 hi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Engineering a vascularized and innervated tissue using a building block approach' (PreVascIn), addressing dissemination and exploitation.

assistant: **Impact**

The current ageing population is faced with an ever increasing shortage of donor tissue for the repair or replacement of damaged tissues. Tissue engineering is a promising strategy to cope with this shortage. However, even though tissue engineering has been an active field of research for several decades, the number of clinical successes is limited. This is often due to a lack of integration and survival of the engineered tissue after implantation.PreVascIn proposes that the integration and survival of an engineered tissue can be significantly improved by including both a vascular and a neural network. Adding both a vascular and a neural network to an engineered tissue greatly enhances the complexity of this tissue. The cells forming the different tissue components each require different local environments to develop properly. This means that the local environment of individual structures need to be controlled and that current standard approaches, such as simply seeding cells within a scaffold material, are insufficient. As a better alternative approach, in this project I propose to use the ‘Living Legos’ building block system, combined with the use of matrix elasticity and local growth factor delivery to control formation of the separate tissue components. This provides a strong control of tissue development, potentially allowing for the engineering of the vascularized and innervated tissue from a single cell source, as will be investigated in this project. The development of the modular and self-assembly properties of the proposed approach has great potential to result in a highly flexible system, easily translatable to other applications and engineered tissues.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Recognition of viral DNA by the innate immune system'.

assistant: **Objectives**

Herpes simplex virus 1 and 2 (HSV1/2) are important human pathogens, causing both acute and recurrent infections leading to serious diseases such as encephalitis, herpes keratitis, genital herpes, and potentially fatal disseminated disease in newborns. Pathogen recognition by the innate immune system is mediated via host-encoded pattern recognition receptors, which recognize conserved pathogen-associated molecular patterns (PAMPs) and trigger the production of pro-inflammatory cytokines and chemokines, including the type I interferons and interleukin 1. Recent studies have demonstrated that DNA may be an important PAMP. However, very little is known about the physiological role of viral DNA recognition in the innate immune response. The proposed project will utilise state-of-the-art technology in cell biology, bioimaging and animal models to investigate the physiologic role of virally delivered DNA in immune activation, and identify and classify the pathways and receptors involved, establishing the host laboratory as a world leader in the field. The overall hypothesis of the project is that HSV infection leads to release of DNA in the cytoplasm of host cells, which recognize the DNA through specific receptors, and initiate a protective innate immune response. Specific aims:Aim 1 – Describe the role of cytosolic viral DNA in initiating the innate immune response to HSV and characterise the mechanism of DNA release from the virion into the cytosol.Aim 2 – Determine the contribution of cytosolic DNA receptors to the immune response against HSV in vivo.Results from the proposed project may aid in (i) identifying potential novel drug targets, (ii) improving vaccine efficacy, (iii) and allowing control of the potential side effects of viral gene delivery systems.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'When saying the world is just backfires: elites' expression of the belief in a just world, perceived immorality, moral outrage and punishment wishes' (BJW).

assistant: **Innovation**

Saying that people get what they deserve and deserve what they get, can be considered as a moralizing discourse. Past research has shown that this “just world” discourse is well regarded when conveyed by ordinary citizens. The main goal of this project, however, is to show that it can backfire against those who enact it. Specifically, this programme intends to show that when financial/political elites resort to a “just world” discourse, it may lead to punishment wishes against those elites, including the use of violence. Indeed, nowadays the financial elite is stereotypically associated with white-collar crime, the consequences of which affect millions of people worldwide; and the political elite is perceived as their accomplice. It is thus hypothesized that when members of the elites, as well-intended and innocent they may be, say that people get what they deserve, they will be perceived as adding insult to injury. Compared to elite members who say that the world is unjust for people, those who say that the world is just will thus be perceived as more immoral; as a consequence, individuals will feel more moral outrage towards them and will wish them higher punishment in various domains (e.g., legal, physical, social). This is a very important issue - after the 2008 financial crisis, various European countries introduced harsh austerity measures. One strategy that political and financial elites used to legitimize these measures was to repeatedly accuse these countries, basically Southern European ones, of having lived beyond their means at the expense of the industrious Northern European. Implicit in this discourse was a collective “just world” one – those measures, as hard as they could be, were deserved. This discourse has contributed to a Northern-Southern Europe div
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Catholicism and the “Negro Question”: Religion, Racism, and Antiracism in a Transnational Perspective (United States and Europe, 1934-1968)' (2014-2020) under Horizon 2020.

assistant: **Objectives**

This proposal aims to investigate how the Roman Catholic Church responded to the issue of anti-black racism from the 1930s to the age of decolonization and the US civil rights movement. What emerges is the Church’s pivotal contribution to the recasting of racial discourse(s) and behaviors. For the first time, the project carries out an overall transnational analysis on this subject, focusing on Catholic “interracialism” as a peculiar third way between racism and anti-racism:• How did interracialism spread and become common sense in Catholicism on both sides of the Atlantic?• Did interracialism really change traditional race thinking?• What were the ideological interactions between American-style interracialism and mainstream European Catholic colonial and postcolonial culture?The starting point will be the figure of Fr. John LaFarge, the American Jesuit pioneer of the interracial movement, and his entourage. The research’s key contribution lies in making a history of the circulation of these ideals across the European press, ecclesiastical networks, and the intellectual panorama, taking into consideration some specific poles, i.e. Vatican environments and three Catholic colonial powers (France, Belgium, Italy). Following a perspective of religious, cultural and transnational history, the project’s main objective is to focus on the inter-crossing of ideologies, images and practices. It will foreground the “speakers” of that discourse, as well as the features and limits of such an interracialism as a “sound” antiracism.The University of Florence and Fordham University will perfectly support the scientific and civil contents of this proposal. The expertise offered by the faculty at these institutions, in tandem with both universities’ resources, is crucial to reaching the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Quantum Tensor Networks and Entanglement' to be submitted under Horizon 2020.

assistant: **Abstract**

One of the major challenges in theoretical physics is the development of systematic methods for describing and simulating quantum many body systems with strong interactions. Given the huge experimental progress and technological potential in manipulating strongly correlated atoms and electrons, there is a pressing need for such a better theory.The study of quantum entanglement holds the promise of being a game changer for this question. By mapping out the entanglement structure of the low-energy wavefunctions of quantum spin systems on the lattice, the prototypical example of strongly correlated systems, we have found that the associated wavefunctions can be very well modeled by a novel class of variational wavefunctions, called tensor network states. Tensor networks are changing the ways in which strongly correlated systems can be simulated, classified and understood: as opposed to the usual many body methods, these tensor networks are generic and describe non-perturbative effects in a very natural way.The goal of this proposal is to advance the scope and use of tensor networks in several directions, both from the numerical and theoretical point of view. We plan to study the differential geometric character of the manifold of tensor network states and the associated nonlinear differential equations of motion on it, develop post tensor network methods in the form of effective theories on top of the tensor network vacuum, study tensor networks in the context of lattice gauge theories and topologically ordered systems, and investigate the novel insights that tensor networks are providing to the renormalization group and the holographic principle.Colloquially, we believe that tensor networks and the theory of entanglement provide a basic new vocabulary for describing stron
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'The european initiative for primary immunodeficiencies (EURO-PID)'.

assistant: **Concept**

Primary immunodeficiency diseases (PID) can often only be studied through transnational collaborations due to that they are very rare. Research and development for PID in Europe is generally considered to be world- leading. This can be exemplified by the fact that many of the PID were initially characterised in Europe, several of the corresponding disease-genes were first identified by European investigators and recently, the first successful gene therapy for any disease (X-linked severe combined immunodeficiency) , was first carried out in Europe. We wish to further promote European collaborations in this field in order to elucidate disease mechanisms by providing the relevant research tools. This will be achieved by developing disease-based registries for mutations and clinical information, by supporting research sample shipments , by arranging guideline and technology workshops and by supporting short-term visits to different laboratories.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'The influence of the cell membrane asymmetry and curvature on the functioning of membrane proteins and the transport of therapeutic compounds'.

assistant: **Innovation**

Real cell membranes are essentially asymmetric and non-planar. Outer leaflets of the plasma membranes contain neutral lipids and glycolipids, while the inner leaflets host practically all anionic lipids and phosphoinositides. In addition to asymmetric composition the membranes are usually curved due to spontaneous curvature of the membrane lipids and an influence of membrane proteins and cytoskeleton. There are many cellular phenomena, which are influenced by the asymmetry and the membrane curvature such as formation of synaptic vesicles, blebs and apoptotic bodies, membrane fusion and splitting, budding of enveloped viruses, endo and exocytosis, etc.In this work we propose comprehensive interdisciplinary study of the influence of membrane asymmetry and curvature on the functioning of integral membrane proteins and the transmembrane transport of therapeutic compounds (such as cisplatin and its derivatives).         The goal is to reveal major physical factors, which distinguish asymmetric and curved membrane environment and govern interactions, orientation and diffusion of the small molecules (drugs) and large integral proteins.The combination of experimental methods (“wet” biochemistry and molecular biology, enhanced infrared and Raman spectroscopy) and computer simulations (coarse-grained and atomistic molecular dynamics, quantum chemistry) would be used in the project in complimentary manner.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Computational modelling and design of responsive industrial fluids', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

Depending on thermodynamic conditions, amphiphilic molecules may self-assemble into wormlike micelles. Entanglements between wormlike micelles create network structures, which impart high viscosity and elasticity to the fluid. This wide range of rheologic al properties, combined with the sensitivity to thermodynamic conditions, makes these fluids perfectly suited for environmentally friendly applications in oilfield industries. By mixing the viscoelastic surfactants (VES) with polymers, the rheological properties required can be obtained at a significantly lower fluid cost. Our goal is to increase the fundamental understanding of the relation between the microstructure and the rheological behaviour of VES-polymer fluids, using computer simulations at the particulate level. This will enable us to design new fluids with enhanced properties and at a lower cost. In the description of VES-polymer systems we discern two levels of detail.At the atomistic level, the interplay between energy and entropy determines t he mesoscopic" properties of the polymers and worms (e.g. size and stiffness) and the energetics of breaking up of entanglements. At a coarser level stiffness and entanglement energetics determine the network structure and hence the viscoelastic properties of the fluid. Dr M. Stukan has created Monte Carlo computer simulation of polymers solutions to study their phase behaviour (PhD work, INTAS grant). He will apply his experience in computer simulation to calculate the visco-elastic properties of mixtures of 'living polymers' (wormlike micelles) and polymers. Experimentalists and computational physicists at Schlumberger will provide the input needed for this work.This project will enable him to further prepare for a career in research by diversifying his scientific