RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'From Inherent Concurrency to Massive Parallelism through Type-based Optimizations'.

assistant: **Innovation**

In a radical paradigm shift, manufacturers are now moving from multicore chips to so-called manycore chips with up to a million independent processors on the same silicon real estate. However, software cannot benefit from the revolutionary potential power increase, unless the design and code is polluted by an unprecedented amount of low-level, fine-grained concurrency detail.Concurrency in mainstream object-oriented languages is based on multithreading. Due to the complexity of balancing work evenly across cores, the thread model is of little benefit for efficient processor use or horizontal scalability. Problems are exacerbated in languages with shared mutable state and a stable notion of identity -- the very foundations of object-orientation. The advent of manycore chips threatens to make not only the object-oriented model obsolete, but also the accumulated know-how of a generation of programmers.Our vision is to provide the means for industry to efficiently develop applications that seamlessly scale to the available parallelism of manycore chips without abandoning the object-oriented paradigm and the associated software engineering methodologies.We will realise this vision by a breakthrough in how parallelism and concurrency are integrated into programming languages, substantiated by a complete inversion of the current canonical language design: constructs facilitating concurrent computation will be default while constructs facilitating synchronised and sequential computation will be explicitly expressed. UpScale will exploit this inversion for a novel agile development methodology based on incremental type-based program annotations specifying ever-richer deployment-related information, and for innovative type-based deployment optimisations both at compile time and a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'The Rationale and Ramification of Sentencing and Punishment in China through a Gender Based Perspective' (RRSPCGBP).

assistant: **Innovation**

The proposed research project plans to explore the rationale and ramification of sentencing and punishment in contemporary China through investigating cases concerning gender and sexual identity, that is, sexual violence, sexual assault of minors/girls, and domestic violence, as well as the abuse of the criminal law in incriminating acts promoting the rights of sexual minorities. This research will provide a much-needed while still under-studied evidence-base, examining the relationship between gender and sexual identity and the criminal justice system in China, analysing to what extent the criminal law is utilised and/or abused in causing human rights violations. Based on the examination, the project will study civil society activism advocating for gender equality and the rights of sexual minorities in China as a critical bottom-up approach to address rights violations in individual cases as well as to advance the protection of human rights more broadly. This in-depth inquiry into civil society activism in the cases concerning gender and sexual identity will form a crucial basis for raising targeted plans and strategies addressing the potential restraints and strengthening its forces in working out effective social changes.   This socio-legal research, drawing upon the qualitative analysis of cases, quantitative analysis of data, desk-based research on multiple disciplines including feminist jurisprudence, criminology, and human rights, and qualitative analysis of primary data obtained through interviews, aims at shedding light on the relationship and interplay between the state and individual citizen, between power and rights, as well as between patriarchy and authoritarianism. It carries a special significance against the current backdrop that democracy and liberalis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Exploiting strong light-matter coupling for organic polariton-based photonic devices'.

assistant: **Objectives**

The coherent coupling of photons and material resonances, known as strong light-matter coupling, has recently emerged as a concept to realise a variety of novel devices. By hybridising light in a micro- or nano-scale cavity with a material resonance, often an exciton to create exciton-polaritons, properties of both light and matter can be manipulated. While this has shown great promise in systems that exploit a change in energy levels of a material, such as in polariton chemistry, the resulting change of light dispersion has been largely neglected for applications. Within the project PolDev, I aim to realise organic polaritonic devices that make full use of the exciton-like dispersion in ultra-strongly coupled microcavities with suitable detuning. In doing so, I will realise interference-based transmission filters with ultra-low angular dispersion that will enable a new way of designing optical systems. I will further exploit this concept to design high-Q microcavity polariton light emitting diodes for display applications with unprecedented colour purity and to showcase new pathways for electrically pumped polariton lasing. The resulting devices will further be ported onto mechanically flexible platforms, paving the way for novel polaritonic applications.


**Keywords:** strong light-matter coupling, polaritons, dispersion, optical filters, organic light-emitting diodes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Scalable Control Approximations for Resource Constrained Environments' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

This project aims at making a breakthrough contribution in optimal control and decision making for nonlinear processes that take place on network structures and are dynamic in time and/or space. The setting has a wide range of potential domains of applicability, comprising thermal, electric, or fluid dynamics in energy networks, logistics, disease spreading dynamics, or cell signalling in biomedicine. The project will pursue the following objectives: To contribute new theory, to develop numerical approximation methods, to implement algorithmic methods in software, and to conduct proof-of-concept studies. Research in the young field of mixed-integer optimal control (MIOC) has recently seen increased momentum together with numerical approximation algorithms and control theory. Despite initial successes, key questions remain unsolved because of a lack of analytical understanding, a lack of tractable formulations, the unavailability of efficient solvers or the insufficiency of existing implementations. This project focuses on pivotal but poorly understood topics: decomposition, relaxation, and approximation; domains admitting homogenization and limiting processes using weak topologies; tractable approximations of direct costs of decisions; efficient distributed and parallel nonlinear solvers; and robustness of approximate nonlinear decision policies under uncertainty. These key issues appear systematically in a wide range of control tasks of high societal relevance.  By addressing them, the project helps to bridge a persistent and pronounced gap in simulation & optimization practice. Due to non-trivial interactions emerging in theory and the unavailability of comprehensive algorithms, these topics cannot be suitably handled by merely combining the respective states of the a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Molecular mechanisms of interferon-induced antiviral restriction and signalling' (ANTIViR) under Horizon 2020.

assistant: **Objectives**

Interferons (IFNs), which are signalling proteins produced by infected cells, are the first line of defence against viral infections. IFNs induce, in infected and neighbouring cells, the expression of hundreds of IFN-stimulated genes (ISGs). The ISGs in turn induce in cells a potent antiviral state, capable of preventing replication of most viruses, including Human Immunodeficiency Virus type 1 (HIV-1) and influenza A virus (FLUAV). Identifying the antiviral ISGs and understanding their mechanisms of action is therefore crucial to progress in the fight against viruses. ISGs playing a role in the antiviral state have been identified, such as human MX1, a well-known antiviral factor able to restrict numerous viruses including FLUAV, and MX2, an HIV-1 inhibitor. Both proteins bind to viral components but their detailed mechanisms of action, as well as the consequences of restriction on the activation of the innate immune system, remain unclear. Moreover, our preliminary work shows that additional anti-HIV-1 and anti-FLUAV ISGs remain to identify. In this context, this proposal seeks an ERC StG funding to explore 3 major aims: 1) unravelling the mechanisms of antiviral action of MX proteins, by taking advantage of their similar structure and engineered chimeric proteins, and by using functional genetic screens to identify their cofactors; 2) investigating the consequences of incoming virus recognition by MX proteins on innate immune signalling, by altering their expression in target cells and measuring the cell response in terms of gene induction and cytokine production; 3) identifying and characterizing new ISGs able to inhibit viral replication with a combination of powerful approaches, including a whole-genome CRISPR/Cas9 knock-out screen.Overall, this proposal will prov
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Prototyping emerging bio-based products from lignocellulose by zero-waste pathways' (PURE).

assistant: **Innovation**

The need: The dwindling fossil resources and their increasing price together with concerns related to greenhouse gas emissions and environmental pollution necessitate an urgent transition to the use of renewable starting materials and the fundamental change of our manufacturing practices to cleaner, more sustainable production routes.The challenge: Existing approaches for bio-based production routes are complex and costly, while oftentimes offering limited or no increase in quality over conventional approaches. Several challenges need to be tackled in order to further unlock the great potential of bio-based production methods. There is a pressing need for (i) simple, zero-waste production routes from raw material to end-product with a minimal number of reaction steps and high-yield; (ii) the discovery of novel, emerging products that are superior to existing ones in terms of properties, performance as well as environmental and health impact.The solution: My ERC Starting Grant (CatASus) has introduced fundamentally novel catalytic methods for the environmentally benign, zero-waste, non-toxic, and cost-efficient production of chemical building blocks that find concrete valorisation potential in a wide array of industries, including pharmaceuticals, food, agriculture and fuels/energy sectors. The proof of concept: Bringing PURE as a sustainable yet cost-effective chemical manufacturing process of valuable bio-based building blocks to the multibillion-euro chemical manufacturing market offers a highly attractive business case. In this PURE ERC PoC, I will explore the commercial viability of lignocellulose as renewable resource for the production of high quality fine chemical building blocks, by performing proof of concept studies: (i) confirming feasibility of upscaling to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Building-integrated photovoltaic technologies and systems for large-scale market deployment' (PVSITES) targeting Horizon 2020.

assistant: **Abstract**

Building-integrated photovoltaics (BIPV) is currently an expansive market. Market analysts estimate a compound annual growth rate of 18,7% and a total of 5,4 GW installed worldwide between 2013 and 2019. One of the main drivers for BIPV market growth in the EU is the increasingly demanding legislation related to energy performance in buildings. The large potential for energy savings in buildings led the EU Commission to adopt the 2010/31/EU Directive on the energy performance of buildings with the objective that all new buildings are Nearly Zero Energy Buildings (NZEB) by 2020. Renewable energy technologies, and in particular the integration of photovoltaic systems in the building environment offer many possibilities to play a key role within the NZEB scenario. Despite this favorable framework for BIPV technology market uptake, initial estimations of BIPV market growth have been subsequently overestimated in the past few years. A series of demands from the stakeholders which have not been properly addressed by the BIPV value chain are the cause for this deviation. These key requirements are mainly related to the flexibility in design and aesthetics considerations, lack of tools integrating PV and building performance, demonstration of long-term reliability of the technology, compliance with legal regulations, smart interaction with the grid and cost effectiveness. Within this context:The objective of PVSITES project is to drive BIPV technology to a large market deployment by demonstrating an ambitious portfolio of building-integrated solar technologies and systems, giving a forceful, reliable answer to the market requirements identified by the industrial members of the consortium in their day-to-day activity. High impact demonstration and dissemination actions will be a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Single molecule mechanical and imaging studies of myosin-V' (MYOSIN-V) under Sixth Framework.

assistant: **Objectives**

The aim of this project is to study the basic mechanisms of myosin-V motility using a combination of single molecule techniques. Many types of cellular motility are based on the cyclical interaction of myosin and actin, coupled to the hydrolysis of ATP. Myosins class V are found in neurons and form dimeric, processive motor molecules moving their cargo along actin filaments for many steps per diffusional encounter. However the basic mechanisms of chemo-mechanical energy transduction and head-head coordination remain unclear.   Based on the host lab previous work I will develop an optical tweezers based technique for ultra-high-speed detection of single molecule mechanical interactions. I aim to combine these mechanical measurements with fluorescence microscopy to correlate mechanical and biochemical states during the catalytic cycle of a single motor head. The next step will be to resolve biochemical states during processive movement of the dimeric molecule.   Specific immobilisation of myosin on substrate surfaces will be critical in these experiments. I will use atomic force microscopy to image myosin-V molecules bound to substrate surfaces and to actin filaments. The experiments will be carried out using recombinant single and double-headed myosin-V constructs expressed in collaboration with JR Sellers lab at NIH. The combination of highly sensitive mechanical measurements with fluorescence will open up new opportunities to characterise protein interactions on the single molecule level in general.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Stratification of Obesity Phenotypes to Optimize Future Therapy', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

SOPHIA will optimise the future treatment of obesity. The challenge is that clinicians, payers and patients view obesity as a failure of self-control, rather than a disease. We will change this perspective by defining subpopulations in terms of (a) the risks of complications linked to obesity, (b) response to various obesity treatments. The subpopulations will be characterised in terms of operational variables (phenotypic, genetic, behavioural, environmental, and omics). These predictive variables will facilitate diagnosis and underpin personalised and protocolised obesity care.  Patient priorities regarding risk and response will influence all aspects of our work. SOPHIA will create a federated database of premier EU cohorts to identify operational variables that are predictive of risk and treatment response in people with and without diabetes. We will validate the predictive value of these variables before creating clinically-useful algorithms to decide “when-to-treat” and “how-to-treat”. Biomarker variables will feed into innovative assays, tests and research targets. We will interpret and analyse our results, to identify shared value across all stakeholders (patients, clinicians, industry, payers). SOPHIA will change attitudes and experience of obesity by (1) demonstrating the heterogeneity of the disease, (2) identifying people at risk of complications, (3) identifying the best treatment for each individual, (4) delivering a common vocabulary and shared understanding of obesity, (5) demonstrating shared value, which combines commercial opportunity with societal benefit.  Our ambition will only be realised if (a) payers agree to fund treatment, (b) industry generate effective treatments, (c) clinicians are prepared to prescribe treatments, and (d) patients are prepa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The genetic architecture of colour pattern evolution in heliconius butterflies' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Despite the extraordinary diversity of color patterns and their clear adaptive value in butterflies, the central question of the mechanisms underlying color pattern change is still poorly resolved. Traditional genetics suggest the existence of clusters of genes (supergenes) modulated by minor genes, that are not homologous between species and suggest prevalence of the genetic architecture in driving adaptation. Developmental genetics suggests regulatory genes are conserved between very divergent taxa, implying a common and labile genetic basis for pattern evolution. My project proposes( 1 ) to build a dense AFLP linkage map for the species Heliconius numata, using techniques used in closely related species. H. numata is a colour-polymorphic mimetic butterfly, and crosses indicate single-gene inheritance of colour pattern with simple dominance of multiple alleles, contrary to what is found in other Heliconius species. We will then(2) compare the produced map to those of Heliconius melpomene and H. erato, using a suite of codominant anchor" loci, including candidate developmental genes involved in colour pattern formation in other butterflies. This will allow us to study the homologies between the two colour pattern genetic systems, and assess the importance of the genetic architecture in determining adaptive change."