RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Characterisation of the role of LHC-related proteins in photosynthesis', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Life on Earth depends on photosynthesis, the conversion of light energy into chemical energy. Light is collected by pigment binding multisubunit proteins, called light harvesting antenna complexes (LHC). The light harvesting proteins of higher plants belong to a large family; these polypeptides comprise up to 75% of the chloroplast grana membrane proteins. Their expression is regulated by the quality and quantity of light. There are a number of proteins in the photosynthetic membranes which show sequence similarity to the light harvesting proteins. These LHC-related proteins are encoded by the so-called Lil (light harvesting like) genes. They include early light induced proteins (ELIPs), one-helix proteins (OHP) and stress-enhanced proteins (SEP). These are short-lived polypeptides which accumulate in the thylakoid membrane during light stress. Unlike LHC complexes their primary function is not light harvesting but rather protection against light stress. There are mutant Arabidopsis lines available lacking these LHC-related proteins. The aim of the project is the detailed characterisation of these mutants including studies of their photosynthetic performances, biochemical and metabolomic characterisations and fitness studies in field conditions. The project will also focus on the investigation of the location and interacting partners of the Lil proteins, which knowledge is necessary for the understanding of their mode of action. The targets of this project will allow a better understanding of the fine-tuned balance of light harvesting and photoprotection, and the responses of plants to light stress, which knowledge will be beneficial to agriculture as well by helping the improvement of crop plants to withstand stress conditions, such as high light exposure.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Smart on-board processing for earth observation systems' (SOPHOS), addressing dissemination and exploitation.

assistant: **Impact**

The number of satellites being launched into orbit is increasing rapidly every year, and with it the complexity anThe number of satellites being launched into orbit is increasing rapidly every year, and with it the complexity and capabilities of each satellite continues to grow dramatically. Today, near full earth coverage by optical sensors is achieved daily by civilian spacecraft, and soon civilian SAR will achieve a similar daily coverage. The ever growing amount of spaceborne data will need new solutions to get that data to the ground, because the available downlink is always a limitation in space system design.   Better on-board data processing and storage will allow future iterations of spacecraft to achieve higher performance in smaller and smaller packages. Current solutions present limitations in computational performance, memory capacity and performance, and data reliability in very small form factors. SOPHOS will design and implement enabling technology for high-end data products produced on-board spacecraft via the implementation of more power efficient high performance space processing chains for various Low-Earth Orbit (LEO) missions, with a focus on Synthetic Aperture Radar (SAR), which is one of the most data intensive space applications currently used. This implementation will be achieved through the optimisation of the payload processing and data storage system accompanied by the use of COTS components and the miniaturisation of high-performance hardware in combination with robust firmware and software with heritage in high-end space applications. SOPHOS will combine state-of-the-art industrial computing technologies (COTS) including high-end FPGAs and GPU equipped SoCs, along with advanced and scalable processing capabilities. The modules developed wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Indigenous Epistemologies and Images of Public Wealth in Amazonia' (IEIPWA).

assistant: **Innovation**

Research focuses on the place of indigenous epistemologies in intercultural and highly politicized interactions that revolve around the interface of development in Amazonia: on the one hand, the external planning and implementation of development projects in indigenous territories; on the other, indigenous people’s own critical responses to such projects. Although we have informative studies of development as a process linked to Western modernity and historicity, we have little sense of how development plays out in the emergence of interethnic identity politics, or what cultural meanings are harnessed in political processes, in particular those that challenge the implicit beliefs of development as well as its practical workings. This proposal is intended to correct that lack through a consideration of native notions of work, wealth, and well-being that come into view during specific development encounters. My analysis is anchored in native epistemologies, as they not only involve sophisticated theories of cognition, agency, and subjectivity, but also inform native senses of history, interculturality, and cultural change. First objective is to show that work, conceived in native terms as the process that materializes intentional thought and speech, is not only a defining element of personal and collective identities, and indispensable to the achievement of public wealth, but it also sustains indigenous self-dependence against assistentialist development programs. Second objective is to gain a better understanding of indigenous epistemologies, particularly as it relates to native senses of self, identity and well-being. Third objective is to show how these indigenous epistemologies are mobilized in intercultural contexts, and sustain indigenous prospects in the modern wor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'EUROPEAN ROBOTIC GOAL-ORIENTED AUTONOMOUS CONTROLLER'.

assistant: **Concept**

European Robotic goal-oriented autonomous COntroller (ERGO)The specific objective of ERGO is thaen to deliver the most advanced but flexible space autonomous framework/system suitable for single and/or collaborative space robotic means/missions (orbital and surface rovers) demanding robust operations with adaptable levels of autonomy.Due to the intrinsic similarities of addressed scenarios, especially for what concerns surface applications, ERGO has to be/and has been thought so to be applicable to terrestrial robotic applications requiring high level of autonomy. In order to achieve this challenging objective, the ERGO team has been settled such to guarantee strong background both in robotics in general and operational autonomous space robotic missions (GMV, ADS, SciSys), as well as state of the art expertise in goal oriented autonomy (GMV),  planning (King College, University of Basel, GMV), guidance and navigation for robotic applications (GMV, ADS, SciSys), formal validation and verification (UGA-UGA), on-board critical software design and development (GMV, Ellidiss ).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'POLYmer microACTuators for biomedicine'.

assistant: **Objectives**

Within the areas of cell biology, biomedicine and minimal invasive surgery, there is a need for soft, flexible and dextrous biocompatible manipulators for handling biological objects, such as single cells and tissues. Present day technologies are based on simple suction using micropipettes for grasping objects. The micropipettes lack the possibility of accurate force control, nor are they soft and compliant and may thus cause damage to the cells or tissue. Other micromanipulators use conventional electric motors however the further miniaturization of electrical motors and their associated gear boxes and/or push/pull wires has reached its limits. Therefore there is an urgent need for new technologies for micromanipulation of soft biological matter.Our aim, in light of this proposed Marie Curie Fellowship, is to develop soft, flexible micromanipulators such as micro- tweezers for the handling and manipulation of biological species such as cells and surgical tools for minimal invasive surgery. This ambitious objective will be accomplished by developing novel patterning and microfabrication methods for polymer microactuators and integrate these microactuators into easy to use manipulation tools. We aim to produce tools with minimal dimensions of 100 µm to 1 mm in size, which is 1-2 orders of magnitude smaller than existing technology.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Integrated ICT Solutions for Smart Personal Protective Equipment for Fire Fighters and First Responders' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

Fostering innovation through Pre-commercial procurement (PCP) has received renewed impetus by the EC and the launch of initiatives in several EU countries. The potential of PCP is generally recognized; however, no large scale projects have been carried out where several countries join their efforts procurers encounter bottlenecks in the implementation of the PCP concept.<br/>Smart@Fire has two main objectives: the first is to tackle a concrete challenge; the second is to create a commonly agreed PCP approach that can be deployed and duplicated in the EU and formulate answers for the identified bottlenecks.<br/>The project tackles a concrete challenge that has been detected commonly by procurers: how to increase the safety of fire fighters and first responders undertaking fire fighting and civil protection work? Fire fighting remains a perilous with a lot of casualties and deaths; the proposed ICT-solutions available on the market at the moment do not yet provide full satisfaction. This translates clearly the innovation expectations from the procurers' side related to smart monitoring or technological advance in equipment. The solution lays in the development of ICT-solutions in Smart Personal Protective Equipment that might prevent injuries or deaths.<br/>Smart@Fire wants to be a groundbreaking pilot project which will implement a PCP trajectory to solve the stated problem that transcends the EU borders. Additionally the project will prove that PCP holds many advantages for public procurers; will investigate the effects of scale and stimulates the exchange of PCP expertise in order to create a PCP approach that works on a European scale. This should pave the way towards an increased amount of joint PCP initiatives to come.<br/>Finally through tangible results, Smart@Fir
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Personalized Drug Response: IMplementation and Evaluation in CKD' (PRIME-CKD), addressing dissemination and exploitation.

assistant: **Impact**

Chronic Kidney Disease (CKD) is one of the major causes of death in high income countries and its prevalence is growing rapidly. New therapies for the treatment of CKD have shown clear efficacy at a population level. Yet, individual patients respond differently with many patients showing suboptimal efficacy. This indicates that a ‘one size fits all’ approach is no longer sustainable. Currently there are no validated pharmacodynamic biomarkers in CKD that aid in guiding optimal therapy for individual patients. Furthermore, there remains a large gap between biomarker research and actual implementation of biomarker based care in daily clinical practice. Thus, there is an urgent need to validate and translate biomarkers as tools for daily clinical practice. PRIME-CKD has a unique advantage to address this challenge as it builds on recently discovered pharmacodynamic biomarkers for CKD treatment, and has access to a vast amount of clinical data, bio-samples. PRIME CKD will: 1)Provide a breakthrough in the pharmacotherapy of CKD with the validation and implementation of pharmacodynamic biomarkers which will advance personalized medicine. 2)Scientifically validate innovative clinical trial elements, pipelines and qualification procedures that can be used by researchers, diagnostics industries and regulatory authorities. 3)Establish a Stakeholder Network to truly engage patients, clinicians and other stakeholders in implementation of personalized medicines4)Develop a roadmap for biomarker use in daily clinical practice for the optimal treatment of CKD. These results will enable clinicians to match patients with CKD with the most effective available drug within the shortest possible timeframe leading to less disease burden and progression of disease, enhanced quality of life and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Supracellular contractility dynamics and cell communication during collective chemotaxis.' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

Collective chemotaxis (CCT) is a fundamental process for embryonic development and cancer metastasis, where groups of cells collectively migrate in response to a chemoattractive signal. While single cell migration depends on polarised actomyosin mechanotransduction and signalling cascades within the same cell, in CCT these functions are shared between different cells to achieve a coordinated, ‘‘supracellular’’ translocation. The molecular mechanisms underlying coordination and cell-cell communication during CCT have been largely overlooked. I propose to address this issue using the neural crest (NC), a highly invasive mesenchymal cell population that migrates throughout the embryo via CCT. NC migration shows extensive similarities with cancer invasion, making it a useful model for studying metastatic migration. Preliminary experiments show that an actomyosin ring-shaped cable, which surrounds the NC cluster, contributes to maintain a supracellular organisation. Also, during CCT, gap junctions appear to regulate synchronous actomyosin contractions in cells located at the cluster’s rear. Therefore, I will study this contractility dynamics in-vitro and in-vivo using Xenopus and zebrafish. I will manipulate the actomyosin cable to understand its contribution to efficient chemotaxis. Then, I will investigate how gap junctions enable synchronisation between neighbouring cells, by imaging the spread of calcium waves in NC clusters and manipulating other diffusible messengers. This study will give significant insights into the mechanisms regulating CCT, which is crucial for deepening our understanding of morphogenesis and cancer biology.


**Keywords:** Collective chemotaxis, neural crest, gap junctions, actomyosin, calcium waves
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how '(International) Socio-Technical Challenges for implementing geological disposal' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

InSOTEC aims at identifying the main socio-political challenges for implementing geological disposal and their interplay with technical challenges. It will furthermore provide the IGD-TP with concrete suggestions on how to address these entangled socio-technical challenges.The biggest challenge today lies in adapting the generic concept of geological disposal to the real world environment (both natural and social) in which it needs to be implemented and with which the whole of the waste management system will need to build and maintain a long-term sustainable relationship. Addressing this challenge will imply searching for a strong and lasting connection between the technical and social aspects of managing radioactive waste.InSOTEC wants to contribute to addressing this challenge by:- Identify and clarify socio-technical challenges for implementing geological disposal (and radioactive waste management in general).- Develop further analytical insights into these challenges by means of a number of case studies on specific topics, addressing the interplay between technical and socio-political challenges.- Advance and facilitate mutual learning, and advise and assist scientists and technological experts to develop the tools and the ability to communicate in a two way process about their work and to engage with stakeholders on technical and safety issues.- Advise the IGD-TP on how to strengthen its position and message to the world of decision-makers, through the integration of a social component within its scope of work by:o Exploring with the IGD-TP how to fulfil its ambition to link a broader range of stakeholders (of which some non-institutional) on a structured basis to the platform’s Exchange Forum.o Making concrete suggestions to the IGD-TP on how to set priorities fo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'RISk and uncertainty in developing and Implementing Climate change pOlicies' (RISICO).

assistant: **Innovation**

Uncertainty is pervasive in all aspects of climate change. Although this is beyond dispute, the vast majority of research assessing climate ignores uncertainty, in large part because of the technical complexities involved. The present project aims at advancing substantially the way we conceptualize, model and frame the climate change policy making process, focusing on the central role of uncertainty.The first step is that of applying state of the art techniques from operation research (stochastic dynamic and approximate dynamic programming) to the realm of integrated assessment models (the conventional tool used to perform climate change analysis). These techniques enable us to capture a wide range of stochastic phenomena in the decision process. However, to really move forward the research edge one needs to shift the focus on to the way we, as individuals, perceive these uncertain phenomena.Indeed, the literature on decision making under uncertainty spans way beyond economics, statistics and operations research: Notably psychology and philosophy. These disciplines have had a major role in extending what we know about the process of decision making under uncertainty, and this project aims at reconciling this strand of literature with that on climate change policy design and assessment. The three main research questions are:1) What are key risk and uncertainty perception issues and “biases” when we face climate change and under what instances should they be included in normative analyses of climate change?2) How can we map these “alternative” representations of uncertainty and risk perception into integrated assessment models and how will these affect the normative predicaments of these models ?3) How can we communicate and frame uncertainty itself, as well as results of