RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Tyre pyrolysis process for cement manufacturing and tyre-to-energy plants'.

assistant: **Innovation**

The aim of this project is to demonstrate a patented tyre pyrolysis process with energy and by-product recovery, first in a cement plant and subsequently in a full scale 17MWe tyre-to-energy power plant. Scrap tyre is undesirable for landfill, but has very high calorific value, and is due to the high natural rubber content a renewable energy source.In tyre pyrolysis combustor scrap tyres are partially gasified producing fuel gas and residual saleable char. In the tyre-to-energy plant the fuel gas is completely combusted in a secondary chamber and is passed through the steam rising boiler used in the steam cycle electric power plant. The ultimate objective of this project is to demonstrate tyre-to-energy plant's long term technical and economical viability.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Sparse Tensor Approximations of High-Dimensional and stochastic Partial Differential Equations' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The present project addresses numerical analysis and algorithmic realization of sparse, adaptive tensor product discretizations of partial differential equations (PDEs) in high dimensions with stochastic data. The aim of the project is to develop mathematically founded adaptive algorithms which are based on sparse tensorization of hierarchic Riesz bases or frames. These will be hierarchic multilevel bases in the physical domain, either Finite Element wavelet type bases or hierarchical, multilevel bases. In the parameter domains corresponding either to random inputs or to phase spaces in transport problems, spectral type representations of ``polynomial chaos'' type shall be employed. Mathematical aim is to analyzed for a classes of elliptic and parabolic PDEs on high or possibly infinite dimensional parameter spaces adaptive, deterministic and dimension independent solution methods with convergence rates superior to those afforded by Monte Carlo Methods, in terms of accuracy vs. complexity. Algorithmic work will address design of data structures with minimal overhead for the efficient realization of the sparse tensor approximations. Applications include space-time adaptive solvers for elliptic, parabolic and certain parametric hyperbolic PDEs, nonlinear approximate spectral representations of nonstationary random fields, scale-resolving solvers of elliptic and parabolic problems with multiple scales with complexity independent of the number of scales, and sparse, adaptive numerical solvers for parametric transport problems. The project will be in collaboration with coworkers in France, Germany, UK, The Netherlands. The project involves mentoring postdocs and predocs who will be actively involved in all aspects of the research, as well as a teaching component.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Bone Proteomics for Neanderthal and Denisovan Genotyping' (BONETAG), addressing dissemination and exploitation.

assistant: **Impact**

Ancient biomolecules have revolutionized our understanding of human evolution. Ancient proteins, in particular, preserve longer than DNA and have the potential to provide crucial insights into the evolution and demise of archaic hominins. The emerging field of palaeoproteomics, which studies ancient proteins, has mostly focused on the analyses of dental material and complete bones. However, smaller bone fragments that are morphologically uninformative—often the most common type of excavated fossil remains— remain an untapped source of important evolutionary information. BONETAG aims to utilize these fragments using recent technological advances and a unique fossil collection, and study the proteins preserved in the bones of our closest archaic relatives: Neanderthals and Denisovans. This will involve comprehensive proteomic sequencing of bones from archaic populations, some of which are linked to high-quality genetic data. BONETAG is the first project that compares ancient DNA and protein data from the same individuals in a comprehensive way. The project will initially focus on the extraction of bone proteins using a series of protocols to enhance protein recovery. This will be followed by the development of a computational method to differentiate the proteomic sequences of Neanderthals, Denisovans, and modern humans. Finally, the two workflows will be applied to a collection of hominin bone fragments that have previously failed DNA analyses but show positive signs of protein preservation. The results, as well as the workflows developed during BONETAG will be shared with the palaeoproteomic community. This will allow researchers in regions with poor DNA preservation to utilize proteins, and achieve reliable taxonomic identifications of morphologically uninformative bone
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Recycling of Lithium from Secondary Raw Materials and Further' (RELiEF).

assistant: **Innovation**

Current recycling technology is focused on recovering Li from battery scrap, while hardly much focus and technological development is going towards other Li sources. Hence the aim is to recover Li from potential secondary sources, in order to reduce unrecovered Li from its waste generation, which is estimated to be approx. 27.33% of the current global Li production. RELiEF proposes an integrated recycling facility for Li from secondary raw material sources with continuous processing to produce battery materials. Li wastes will be reduced by more than 70%, which will instead be recycled into high value battery-grade material. The results of the integrated and continuous process up to battery precursor recovery will be demonstrated at TRL 5 and battery active material closed-loop process will be demonstrated at TRL4 with a 1.5 – 2.5 kg/week output of battery active materials and a new business model will be developed for the materials acquisition and processing, taking into account environmental and social sustainability. The expected results will contribute to decreasing the dependency of the EU on imported battery chemicals and raw materials. RELiEF will greatly strengthen the EU’s competitiveness in the battery storage value chain.The RELiEF consortium consists of 12 partners, six of which are SMEs (ABEE, EXT, EURICE, IST, PEG, TC), four are non-profit RTOs (IMNR, INEGI, ZSW, NOVA) and further two are universities (LUT, ULB) and one associated industrial partner (LANX), Thus, it a very high amount of industry involvement, entirely in the form of innovative SMEs covering the technological and also the impact maximization related aspects of the project; a perfect combination of basic research methodologies, chemical process and analysis capabilities, technology developme
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Development of superabsorbent biomaterials based on oat protein through electrospinning and 3D printing', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Superabsorbent materials (SAMs) can absorb and retain large amounts of water (>10 times their weight). Hence, they have many applications, such as soil conditioners, diapers, menstrual pads, and wound dressings. Thus, in 2021 SAMs global market was valued at $8.6 billion. However, one of the main concerns about their use is that they are often based on acrylic acid and polyacrylamide, which are petroleum-derived, difficult to degrade, and their degradation products could be toxic. The superbiOmAT project will take this challenge by developing SAMs based on oat protein (OP). The specific objectives are to increase water binding capacity of OP through chemical functionalisation, to process OP through electrospinning and 3D printing, and to evaluate the potential of superbiOmAT in different applications. OP is an under-exploited by-product after β-glucan extraction. However, its high lysine content makes it a good target for functionalisation by acylation to enhance its water binding capacity. Electrospinning and 3D-printing could be particularly interesting for developing SAMs, yet not fully explored for protein matrices. The superbiOmAT project will revalorise OP and open a portfolio of new bio-based SAMs. A commercial interest in the results of this project is expected and protection of IPR will be prioritised. Amongst general public and targeted audiences, the project will raise awareness of the pollution created by petroleum-derived SAMs and their potential toxicity. This project is in line with a more sustainable production system and the 17 Sustainable Development Goals (UN Agenda 2030). superbiOmAT will be carried out by Dr. Barbara Tomadoni with the supervision of Prof. Antonio Guerrero at University of Seville, Spain. The researcher will gain maturity and indepen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Lignin utilization in mycelium-based biocomposites from recycled wood' (LignoMBB), addressing dissemination and exploitation.

assistant: **Impact**

We have reached a point where we have to use recycled wood, which is mostly contaminated, to a greater extent because there is a shortage of raw wood in the EU. At the same time, in pulp mills, we produce large amounts of lignin, however, use it mainly for energy purposes.LignoMBB is bringing technology for the production of mycelium-based biocomposites (MBB), during which recycled wood is decontaminated. Secondly, LignoMBB is using lignin, which is currently mainly used for energy and is understood as a by- or waste product, in order to achieve better mycelial growth on the developed substrate. I am the first to suggest enriching the substrate for the production of MBB with lignin, expecting that the addition of lignin will result in better mechanical properties of the MBB. LignoMBB develops materials only from recycled wood and lignin, i.e. it does not use agricultural residues, as is currently common practice, and does not endanger food security. At the same time, it finds application for large volumes of old contaminated wood, which is currently entering circulation. My first objective is to develop a technology for the material use of lignin and a substitution technology of agricultural residues in MBBs with lignin and recycled wood. Then, I will answer the questions: To which extent additional lignin in MBB is consumed by fungi? What are the limits of substrate enrichment by lignin? In accordance with the second objective, I will develop a novel MBB to be used in structural applications. At different stages of the MBB cycle, I will measure the VOC emissions because I am hypothesizing that the production process of MBB can act as bioremediation and decreases VOC emissions from materials.LignoMBB will be implemented at BOKU in Bio-Resources & Technologies Tulln grou
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Corline Heparin Technology - Enabling Regenerative Medicine'.

assistant: **Objectives**

Regenerative Medicine (use of cells and tissue to replace or heal impaired functions in the body, RM) is one of the fastest growing areas in today’s medicine, and has the potential to offer treatment to patients with diseases that are currently untreatable. In many new areas of RM there is however a need to improve the outcome of RM concepts and technologies for it to become a viable option to traditional medicine, or even to motivate the risk of clinical trials and treatments. One of the main problems in several RM areas is that a large portion of the cell and tissue material is lost or made dysfunctional during and shortly after transplantation and that the transplant does not connect to the host tissue as a functional new graft. The specific scientific objective of this project is twofold: 1) to clinically test and prove that Corline Heparin Surfaces (CHS) can be used to protect donated human insulin producing cells that are transplanted to severe cases of Diabetes Type 1 patients, and 2) to broaden the application of the technology and show that the CHS technology can function as a protective and revascularization promoting technology for other Regenerative Medicine areas. The goal is to show CHS’s further applicability to Liver Cell therapy, Xeno transplantation of Islet of Langerhans and to Tissue Engineering In addition to the detailed scientific objective, this project has a specific technological objective. The technological objective of this project is to, in partnerships with the participating SMEs, improve European top grade clinical Regenerative Medicine products by combining them with the CHS technology, transferring the application knowledge and integrating the CHS technology into the partners’ cell and tissue production processes, and to set up a reliabl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Visindavaka 2010 - Researchers Rock!' under Seventh Framework.

assistant: **Concept**

Never before have researchers, their existence, efforts and work, been so important for the Icelandic economy and society. The economic collapse has forced people to reassess their values and as a result, there will be a considerable restructuring of society with important decisions being made about the future development of the economy. In these extreme conditions, innovation and creativity, research and development are blossoming in most sectors and especially within the research community itself. The main concept of the proposal is to bring researchers in direct contact with the public at large and promote a recognition of their role in contributing to the development of European society as a whole. The objective is to influence a more positive public perception of researchers as persons by protraying their many facets and facilitate active dialogue between scientists and guests at Researchers’ Night.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'A knowledge Network for solving real-life water problems in developing countries: Bridging contrasts' (ANTINOMOS), addressing dissemination and exploitation.

assistant: **Impact**

The proposal aims at contributing to global and local knowledge networks for solving real life water supply and sanitation (WSS) problems in developing countries in view of reaching the MDGs. Based on an account of failures of WSS interventions in the last decades, ANTINOMOS aims at making an impact through bridging contrasts (between conceptual approaches, or between perceptions of global and local knowledge networks) and knowledge gaps (between knowledge areas which have only recently been recognized by decision makers as a key issue in reaching the MDGs).The core part of the proposal will be devoted to try to bridge these contrasts and knowledge gaps. For this purpose, special attention will be devoted to link state-of-the-art technological advancement in WSS with local resources and grassroots innovations, in order to enable context-specific learning opportunities for more sustainable solutions to real water problems. First, based on a systems approach, a number of technological systems and practices for WSS will be studied and analysed. Both technological systems based on outside knowledge", i.e. "expert knowledge" as well as systems based on "inside", i.e. "indigenous knowledge", will be studied. Then, special learning devices and knowledge management tools will be developed (where feasible in cooperation with international and local knowledge networks) and applied, in order to foster cross-fertilization between knowledge frames and global-local interaction.Involvement of key decision-makers and change agents at the local level will be a key step to facilitate uptake and integration of solutions in real life. In this perspective, the two primary objectives of the proposal will be: 1. Bridging contrasts and antinomies through the development of learning spaces acro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Scatter correction methods in emission tomography' (1994-1998) under Fourth Framework.

assistant: **Objectives**

Research objectives and content The image quality in Positron Emission Tomography and Single Photon Emission Computer Tomography is of great importance for diagnosis and medical research. Some methods have been separately developed for PET and SPECT to correct the effects of attenuation and scattering of emitted photons. Since current methods show different limitations, a new implementation is needed which accounts for the situation in 3D imaging in the body. The key feature of this proposal is the extension of scatter corrections for both PET and SPECT by means of Monte- Carlo simulations and 3D data acquisition protocols. In this project, measurements will be performed which simulate the situation in clinical SPECT and PET studies. With these data, different algorithms can be tested. Training content (objective, benefit and expected impact) The goal is to develop new extended scatter correction methods in SPECT as well as in PET: Practicable solutions must be implemented, characterised by measurements and connected to the attenuation corrections which already exist. Improved image contrast and qualification of tracer distribution will be the results. This project will be performed in a research group investigating several aspects of improvements in medical imaging. Therefore, instrumentation, reconstruction and other correction methods will be part of the training. Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Uncovering targets for ex vivo expansion of hematopoietic stem cells to enhance cell therapies of blood disorders' in the context of a Horizon 2020 call.

assistant: **Objectives**

Mechanisms of self-renewal in hematopoietic stem cells (HSCs) have been subject to intense studies during the last decades. However, this is still a poorly defined process and very limited progress has been made in the long sought goal of expanding HSCs ex vivo to allow for critical improvements of bone marrow transplantation procedures for cancer patients and potentially a broader use of HSCs in gene therapy and regenerative medicine. The aim of this research program is to systematically identify and characterize regulators of self-renewal in human HSCs and to develop strategies for stem cell expansion. Within the project we will develop novel paradigms for CRISPR (clustered regularly interspaced short palindromic repeats) mediated gene editing in primary human HSCs to enable detailed assessment of gene function. We will further employ forward genetic screening approaches based on both CRISPR/Cas9 gene editing and RNA interference (RNAi) gene silencing to identify regulators of renewal and differentiation in human HSCs. Large numbers of HSCs will be targeted with genome-wide lentiviral CRISPR (sgRNA) and short hairpin RNA (shRNA) libraries. Screening assays for HSC self-renewal will be evaluated in a pooled format and de-convoluted using next generation sequencing, allowing thousands of perturbations to be assayed in parallel. Candidate genes from the screens will be studied further using genetic barcoding and transplantations assays in immundeficient mice to test whether they can be targeted to induce expansion of HSCs ex vivo. Finally, based on our findings, we aim to develop GMP compatible conditions for HSC expansion in preparation for clinical trials involving expansion of umbilical cord blood derived stem cells to treat patients with acute leukemia.