RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Fast beam storage and fragment imaging methods for uv and vuv photodissociation of molecular ions' in the context of a Fifth Framework call.

assistant: **Objectives**

Detailed studies of photo dissociation give insight into the dynamics on excited state potential energy surfaces that are of fundamental importance for understanding reactions of molecular systems. Photo-dissociation processes also play a significant role in atmospherical and astrophysical models. It is proposed to build anew experimental system for studies of photo dissociation of small atmospherically and astrophysical relevant molecular ions. It will be used with pulsed UV lasers and also matches the requirements of a proposed experiment at the new TESLA Free Electron Laser facility.Briefly, in the experiment small molecular ions are produced, stored in an electrostatic ion trap at energies of several kilo electron volts (keV), extracted, and brought to interaction with laser radiation. All fragments emerging from the ion-laser interactions are detected with two imaging detectors. Ion storage allows the initial state of the ions to be prepared prior to the interaction with the laser light, and high incident ion velocities allow efficient imaging of all fragments. The composition and internal excitation of the fragments can then be deduced from the reaction kinematics providing a detailed view of the photo fragmentation dynamics. Among the first systems to be studied is the photo fragmentation of chlorine oxide anion, which is relevant for the chemistry of the ionosphere, and the dissociation of small positive carbon hydrides of relevance for modelling of the interstellar space.The applicant has already research experience with molecular physics using fast ion beams, ion trapping, and imaging detection in individual experiments. The possibility to combine this knowledge in a new experimental setup to study photo dissociation of atmospherically and astrophysical releva
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Optimisation of Friction Stir Welding (FSW) and Laser Beam Welding (LBW) for assembly of structural aircraft parts'.

assistant: **Objectives**

Riveting is the defacto method for the assembly of aluminium aerostructures, with large commercial aircraft fuselages typically containing 100’000s of rivets. However, riveting is known as a time-consuming, expensive and weight-adding operation. From a design perspective, it also places holes and point loads in a cyclically pressurised structure, subject to long-term fatigue loading and corrosion.  Thus is not an ideal solution for these types of structures.With developments in precision laser beam welding (LBW) and friction stir welding (FSW), it is now possible to fabricate “rivetless” aluminium aerostructures using welding processes. These new processes produce a lighter weight, distributed load path with the potential for enhanced strength and structural stiffness, ‘no holes’ and a smoother (more aerodynamic) surface. In addition to being more structurally efficient, the new processes are cheaper and reduce inspection & maintenance requirements.The OASIS project will establish and demonstrate the cost-effectiveness of manufacturing aluminium aircraft structures using the latest developments in LBW and FSW (with appropriate inspection to aerospace standards).  The project is led by TWI, who are leaders in both LBW and FSW techniques. Together with 6 other European organisations, we will design, demonstrate and evaluate the suitability of a range of process variants in creating optimised aluminium aircraft structures, including appropriateness for emerging alloys (e.g. 3rd generation Al-Li, 2nd gen Scalmalloy®).  ESAB who will offer a commercial route for adoption of suitable processes; as suppliers of both LBW and FSW solutions to the European aerospace supply-chain (and who hold unique FSW IP).The impact of OASIS will ultimately allow improved design and manufacture
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Bioprocessed wood fibres for composites and food packaging materials' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

The project develops novel technologies for production of value-added food packages and composites based on renewable materials by enzymatic and chemo-enzymatic methods. The generic goal of the project is to develop widely applicable novel technologies. Enzymes needed in the fiber modification will be selected, characterized and produced in pilot scale with an optimized strain. The adhesion of fibers with biopolymers will be improved by direct radical binding, hydrophobisation or bridging by using enzymatic and chemo-enzymatic methods. The effects will be analyzed. The most promising fibers will be converted in laboratory scale with biopolymers for load bearing composite materials and food packaging materials. Case studies with prototypes will be used to demonstrate the potential of the materials in composite and food packaging materials and to evaluate their economical and environmental competitiveness.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Structural and functional analysis of a gene associated with differentiation and transformation in rat brain' (1994-1998).

assistant: **Concept**

Ethylnitrosourea-induced tumorigenesis of the rat nervous system provides a model for the molecular analysis of cell-type specific carcinogenesis. In the peripheral nervous system, a specific point mutation of the neu (ErbB-2) gene is critically associated with the initiation of malignant transformation in Schwann precursor cells. In rat brain, the RB13-6 monoclonal antibody recognizes a differentiation antigen transiently expressed by a subset of glial cells highly sensitive to ethylnitrosourea-transformation. The corresponding cell-surface antigen (gpl3RB13-6) is a glycoprotein related to the human and murine plasma cell glycoprotein PC-I. The cDNA and parts of the rat RB13-6 gene have been sequenced. In order to clarify the possible role of gp 130RB13-6 in the tumorigenic process, this project includes: (a) mapping and functional analysis of the 5 regulatory region of the RB13-6 gene; (b) mutation analysis of this gene; and (c) study of the phenotypic changes in cells expressing wild-type or mutant RB13-6 transgenes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Precision Cancer Medicine Pipeline and Services'.

assistant: **Objectives**

Cancer cost the EU €126 billion in 2009, while in 2010 the US spent a staggering $124.6 billion on treating cancer.  This cost is set to rise as the effects of an aging population and increasing life expectancy take their toll. These market drivers will put an intolerable strain on health services across the western world, forcing governments to streamline their health services. Current cancer treatment is based on the ""average cancer patient"", meaning some cancer patients may not respond to the treatment while others do. Thus it is clearly is a need for solutions that offer precision cancer medicine.PubGene AS aims to pursue a major market opportunity by developing a complete pipeline for precision cancer medicine (PCMPS), that include the necessary steps from Next Generation Sequencing to clinical treatment support for cancer patients. The biggest beneficiary of PCMPS will be the patient, who will receive a personalized treatment rather than a “hit and miss” approach to therapy. This will improve patient outcomes and ensure patients no longer have to suffer harsh side effects from non-efficacious treatments. The second beneficiaries will be the health providers and payers, as doctors will no longer waste time and money prescribing ineffective treatments. Nevertheless, despite the benefits of personalized cancer medicine, it is crucial to validate and demonstrate the benefits of this type of cancer medicine before large-scale commercialization.PMCPS is an opportunity for PubGene to expand our suite of applications and enter into complete new market for PubGene - targeting the treatment market. The project will give us a head start in providing tools in the field of personalized cancer medicine, ensuring us strong positions in the future European and worldwide markets
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'FETALIX - REJUVENATING THE SPINE TO SET YOU FREE' (FETALIX) targeting Horizon Europe.

assistant: **Abstract**

Joana Caldeira is a forward-thinking researcher, PhD in Biomedicine and FETALDISC’s CEO, whose passion is to contribute to the generalized life quality improvement of an increasingly ageing society. Following her expertise as a researcher in the field of extracellular matrix modulation, improving current regenerative therapies, namely intervertebral disc disease, Joana was faced with a problem that is many times overlooked: Low Back Pain (LBP). Although it may pose as a straightforward health condition to address, LBP, frequently caused by intervertebral disc degeneration (IVDD), affects up to 80% of the population, having a tremendous socioeconomic impact. This condition often requires expensive, lengthy, and invasive treatment, which rarely treats the underlying disease, impacting patient’s life quality by affecting mobility, ability to work and sleep. Moreover, this health challenge is also prevalent in the canines, with many breeds suffering from continuous pain, limited mobility, and immobilization at older ages. To address this challenge, Joana founded FETALDISC, LDA to mainstream innovative, and sustainable deep tech biomedical solutions, especially for IVDD treatment, having FETALIX as its core product – THE FIRST REGENERATIVE FETAL-INSPIRED BIOMATERIAL TO TREAT LBP. The solution will change the market dynamics, by achieving better intervertebral disc regenerative results, being more affordable and eliminating existing treatments setbacks. The company’s biggest challenge is to master business and market insights to track investors’ interest, undertake clinical trials, and certification, and thus launch FETALIX into the market. Women TechEU support will be paramount for the company’s business and market robustness, as well as its scale-up through consolidating it
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Spin Polarization Effects in Catalysts studied with x-ray specTRoscopies at Ambient conditions' (SPECTRA) targeting Horizon Europe.

assistant: **Abstract**

It is nowadays well known the urgent need of cheap, green and efficient catalysts able to convert greenhouse gases into more valuable and recyclable hydrocarbons. In this context, magnetocatalysis is an extremely promising field: in the last few years, a growing number of researchers discovered enhanced performances for electrocatalytic reactions in ferromagnetic materials. The majority of these studies report empirical results, and a satisfactory explanation of the mechanism ruling the spin effects is not well understood, mainly due to the lack of suitable experimental techniques. Regarding thermocatalytic reactions (such as CO oxidation or CO2 hydrogenation), studies on the effects of applied external magnetic field and intrinsic magnetic order on the activity and selectivity of magnetic catalysts are almost completely missing. This project aims to systematically unveil the mechanisms ruling the spin effects in catalytic solid/gas reactions; for the first time, we will simultaneously characterize the magnetic and electronic properties of the single chemical species constituting spinel ferrites catalysts during different solid/gas reactions in operando conditions, with and without the presence of an applied magnetic field. This will be possible through the development and application of a reaction cell that will allow to perform Soft X-Ray Magnetic Circular Dichroism experiments in operando conditions: this will be done modifying the pre-existing operando Soft X-Ray NEXAFS reaction cells developed at the APE-HE beamline of Elettra Synchrotron. The cell will be installed at the SPECIES beamline of MAX IV Synchrotron and the measurements will be conducted exploiting the available circular polarized Synchrotron Radiation. Together with complementary techniques and offline
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'high-Coherence, ultraCold electron diffraction for molecular movies of membrane Proteins' under Horizon Europe.

assistant: **Concept**

Imagine we could make movies of proteins in action. In this project, I propose to develop a unique, table-top setup based on the diffraction of ultracold electrons that does exactly that: make molecular movies of proteins, in particular of the important class of membrane proteins. This tool could revolutionize biochemistry, yielding an ultimate view of natures molecular machinery, and helping scientists to understand membrane-protein-related diseases and develop highly targeted medicines.A unique source, developed at the TU/e and based on the femtosecond photoionization of an ultracold gas, generates electron pulses that should in principle be sufficiently short, intense and coherent to enable electron diffraction on 2D crystals of membrane proteins. In this project I will evaluate the sources capability to generate high-quality diffraction patterns from 2D crystals of e.g. hydrophobin and bacteriorhodopsin. Next, I will measure a sequence of such diffraction patterns in a pump-probe experiment, to obtain a molecular movie of the light-induced conformational change of bacteriorhodopsin. This will be the first protein molecular movie ever obtained on a table-top setup. In parallel, I will improve the source performance. Accelerating the electrons to higher energies (from 10 to above 100 keV), I can keep the sample in its native, aqueous environment inside a Liquid Cell, which strongly extends the applicability of the setup. Modifying the spatial and spectral properties of the ionization laser, I expect to be able to increase the number of electrons per pulse, allowing single-shot diffraction patterns, and to further increase transverse coherence, reducing the required crystal size. Finally, I will seek to improve the coherence of the source to the point where I can apply
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Circular Processing of Seawater Brines from Saltworks for Recovery of Valuable Raw Materials' (SEArcularMINE) targeting Horizon 2020.

assistant: **Abstract**

In this proposal, we build on the ancient and still widely used process of saltworks, where seawater goes through natural evaporation and fractionated crystallization in shallow basins. This process produces sea salt and a brine (bittern) free of calcium as a by-product, which is 20 to 40 times more concentrated than seawater in some crucial elements. The SEArcularMINE project uses this bittern, targeting Magnesium, Lithium and other Trace-Elements belonging to the alkaline/alkaline earths metals (e.g. Rb, Cs, Sr) or transition/post-transition metals (e.g. Co, Ga, Ge) group. Three innovative technologies will be developed and integrated within a circular approach, based on three different processes: 1) reactive crystallisation; 2) selective membrane separation; 3) selective sorption/desorption. The concept is enhanced by: i) energy-efficient concentration steps, ii) on-site generation of reactants from the available brines and iii) production of the required energy from reverse electrodialysis fed with the process outlet brine on-site and solar or wind energy. A multi-disciplinary approach will be adopted for bringing the low TRL of the three main technologies and of the overall integrated concept up to TRL4-5. There will be fundamental advances in the knowledge of the processes, leading to break-through developments of the 3 most important technologies for the recovery of minerals from brines, but also from seawater or any other kind of metals-rich solution.Within our circular strategy, we will look also at the option of including desalination upstream from the saltworks, providing freshwater to the local communities and a concentrated stream to feed the saltworks, increasing salt productivity and bittern availability.The adopted approach will have positive effects on
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Implement metrics with best cost/benefit ratio' (ASAMETRICS).

assistant: **Innovation**

The overall goal of the PIE is to strengthen the competitiveness of Schneider Automation GmbH (ASAD) by improving continuously our software development and maintenance process. The technical objective is to define, implement and evaluate a metrics system for our software development process with the best cost/benefit ratio.THE EXPERIMENTThe PIE will be performed on a baseline project. In addition one or two other projects will be used for verification purpose. In the first step we will apply and test distinct metrics approaches on different phases of the software process of the baseline project. Next we will select those types of metrics with the best cost/benefit ratio and practise them in other projects. The results of these experiment swill be carefully recorded, analysed and evaluated to find our best choice.Finally the experience and knowledge learnt form the PIE will be disseminated both within our organisation and to external audience. In order to assure an efficient approach for the PIE we will involve appropriate consultancy.EXPECTED IMPACT AND EXPERIENCEAfter the PIE there will be a well established metrics system all over the software life cycle. The knowledge of the PIE and on metrics widespread in the company. The created experience database will help to develop future products with higher quality and reduced development time.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Characterization of secondary organic aerosol from photooxidation of isoprene and alpha-pinene with mass spectrometric approaches' in the context of a Sixth Framework call.

assistant: **Objectives**

Biogenic volatile organic compounds (BVOCs) play an important role in atmospheric chemistry and give rise to secondary aerosols, which have effects on climate and human health. A considerable lack of knowledge exists concerning the formation of new particles from BVOCs and the organic chemical composition of natural aerosols.The objectives of the current proposal include the identification of particulate-phase oxidation products of isoprene and alpha-pinene, comprising humic-like substances, and development and deployment of novel analytical techniques and procedures thereby.Characterization of the chemical structures of particulate-phase oxidation products of isoprene and alpha-pinene can provide important fundamental insights into formation mechanisms of secondary organic aerosol (i.e., homogeneous/heterogeneous/mixed phase processes).For reaching the objectives we will examine archived and newly collected aerosol samples from both laboratory experiments and field campaigns at forested European sites, which exhibit large concentrations of the 2- methyltetrols and 2-methylglyceric acid (these are recently discovered particulate-phase photo-oxidation products of isoprene).Unknown compounds that occur at important levels in gas or liquid chromatograms of the sample extracts will be structurally characterised, whereby extensive use will be made of gas chromatography/ion trap mass spectrometry in the electron and chemical ionization modes and liquid chromatography/ linear ion trap mass spectrometry using electrospray ionization in the positive and negative ion modes.For the structural elucidations, the mass spectral data will be interpreted in detail and use will be made of deuterium labelling, collisional activation and accurate mass measurements.In the case of unknowns o