RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Institutions and Society: Towards a Critical Theory of Economic Institutions'.

assistant: **Innovation**

The global financial crisis of 2007-2008 that was followed by The Great Recession and European sovereign debt crisis caused the biggest economic downturn since the Great Depression in 1930s. In Europe, the economic crisis developed into a serious political challenge to the (economic) institutions of monetary union and the existing institutional framework of the European Union as well. The future of the institutional framework of the EU will vastly depend upon a comprehensive theoretical and interdisciplinary assessment. Although academic study of the subject of (social) institutions is on the rise in ethics, sociology and politics, it remains unjustifiably underdeveloped in economics. The proposed study investigates the possibility of devising a critical theory of institutions in general, and of economic institutions in particular. It expounds critical contributions to the understanding of economic institutions from a variety of disciplinary fields and it contributes to the establishment of a multidisciplinary account of social validity, economic function, ethical normativity, and political foundation. Additionally, it would represent a landmark study in critical theories of economic institutions – filling a definite gap in the literature, offering a first dedicated and exclusive delineation of a critical theory of economic institutions. Finally, it would act as an instructive case study, offering an indispensable resource for scholars of economic institutions, and provide a robust analytical framework for the assessment of raison d’etre of institutions and institutional reform. With an eye to project's overall success, the study will be conducted at an academic environment of leading experts on critique of political economy and critical theory. Hence, it will endow the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Transformational uses of dye Plants on Linear B tablets. New approaches to cultural identity and technologies in the Bronze Age Aegean'.

assistant: **Concept**

At the cutting-edge of the scientific scene for their being the first written attestations from Europe, Bronze Age Aegean scripts are crucial to define the linguistic roots of Europe. To achieve this, Linear B is the key area to analyse since it is the only Aegean script embedding elements of different cultures and origins. My research takes on the first systematic study of Bronze Age Aegean cultural identities by way of a very telling case study: processes transforming dyeing plants into finished goods (dyed textiles and perfumes). My aim is to show how the knowledge coming from the transformational uses of dyeing plants transcends how the final product is perceived visually to address what is being communicated culturally. Also, this study will provide ground-breaking information for the history of dyeing processes and bring new data to the use of natural and renewable resources, one of today’s most relevant and timely challenges. It will also implement studies on gender by examining the social construction of gender identities through dyed goods. This project will bring together Mycenaean studies and Indo-European linguistic perspectives and methods, material culture studies and Aegean epigraphy expertise, experimental textile archaeological knowledge and ancient technologies awareness to develop new understandings of linguistic and cultural interactions. I will complete this project in a leading multi-disciplinary research team, with solid scientific expertise and a worldwide network in the topics involved. I will bring philological and linguistic skills that will facilitate research in the group and the transfer of ideas. The proposed work will expand my experience, research competencies, and professional networks. The training and the knowledge transfer as well as
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Sea300' (SEA300).

assistant: **Innovation**

The overall objective of the SEA 300 initiative is to support demonstration of European semiconductor manufacturing equipment in the global conversion process to 300 mm wafer processing. This will be done by Attraction of IC manufacturers from all over the world to Demonstration Test sites,Provision of 300 mm wafer (blank and processed), metrology and analytical services,Dissemination of equipment test results to potential customers.To reach the above mentioned objectives a Dissemination Centre will be established at RAL (UK) and a Service Centre at GRESSI (F).International and national initiatives as I300I in Austin (US) and SELETE in Yokohama (Japan) have been launched to ensure 300 mm semiconductor manufacturing equipment is available at the right time at lowest possible costs and risk. The equipment to be demonstrated as well as the still very expensive 300 mm silicon wafers are expected to be provided for free. Under these conditions only a few European equipment suppliers are able to participate in such demonstration tests in different places in the world. Many of them need tests and the corresponding services also in Europe. As part of the SEA initiative SEA 300 offers the European equipment companies a phased and effective path to 300 mm activities.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'The cell surface tetraspanin web drives tumour development and alters metabolic signalling', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Cancer development is characterized by uncontrolled proliferation, cell survival and metabolic reprogramming. Tumour cells are surrounded by a fluid-mosaic membrane that contains tetraspanins (Tspans) which are evolutionary conserved proteins important in the formation of multiprotein complexes at the cell surface (‘tetraspanin web’). Increasing evidence indicates that Tspans are involved in cancer, still the architecture of the Tspan web in native tumour membranes and its (patho)physiological functions have not been resolved. Based on my preliminary data, I hypothesize that tumour cells contain a disrupted Tspan web in which Tspan interactions are modified leading to aberrant metabolic signalling and tumour development. This is supported by my discovery that loss of Tspan CD37 leads to spontaneous lymphomagenesis due to activation of the Akt survival pathway. The overall aim of Secret Surface is to unravel the composition, physiological functions and molecular mechanisms of the Tspan web on tumour development and clinical outcome. To achieve this, I will focus on studying lymphomas using a multidisciplinary approach: I. Detailed analyses of Tspan web composition in lymphoma to select clinically relevant Tspans (high-throughput tissue microarray technology, multispectral imaging). II. Resolve the endogenous Tspan web on lymphoma cells (super-resolution microscopy), and generation and analysis of lymphoma cells that have a complete deficiency of multiple Tspans (CRISPR/Cas9 technology). III. Decipher molecular mechanisms underlying Tspan web function in lymphoma cells (membrane organization, membrane-proximal signalling, metabolic reprogramming). With my unique toolbox of Tspan knock-outs coupled to advanced microscopy and metabolic studies, I expect that Secret Surface
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Efficient Painting & Enhancement of Hand-drawn Cartoon Animations' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The aim of ToonPaint project is to develop practically usable tool that will make the traditional cartoon animation production pipeline less tedious and so cost effective. In addition to that it will also develop a new enhancement technique to increase visual richness of resulting imagery while retain the look of hand-drawn animation.The project has two main research objectives: (1) develop an efficient variant of LazyBrush algorithm proposed in the previous FP7 IEF project CARToon of which advantage is that it is applicable to a broad class of different drawing styles and requires significantly less manual effort as compared to previous approaches, (2) deliver new interactive tool allowing artists to paint withhand-drawn textures like with homogeneous colors and so enable creation of new painting styles.Besides research objectives the project also proposes a number of complementary activities to support lasting professional integration of the applicant into the host institution. They include establishing own research group, collaborating with industry, improving writing & publishing skills, teaching own master degree course, and preparation of international FP7 ICT project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Human Traffickers: The social circuits of human trafficking and transnational, organised crime' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

During the past two decades, millions of euros have been spent by national governments and international organisations on combatting human trafficking and on offering assistance to victims of trafficking. However, we know surprisingly little about the people who facilitate, manage and orchestrate human trafficking: the traffickers. But who are the human traffickers, if we look beyond the stereotypes? The TRAFFICKER project will answer this question and fill this knowledge-lacuna, by ethnographically investigating the business operations and social relationships of human traffickers, via the analytical concept of ‘social circuits’.The project is based on ethnographic fieldwork in two sites, in respectively one country of origin and one destination country of the traffickers: (a) the city of Galati in Eastern Romania, and (b) in prisons in Lisbon, Portugal, among inmates that are incarcerated for human trafficking. The TRAFFICKER project builds on my extensive research and fieldwork experience within the fields of transnational crime, third-party facilitation/pimping and sex work. This background is essential to the project, since it provides access to the necessary local networks, as well as providing the needed methodological knowledge and ethical awareness.The project illuminates:1) How human trafficking is carried out by traffickers on the ground, and thus how national criminal networks make their illegal business transnational.2) The ways in which the kinships relations and social relationships of human traffickers hinder or enable their transnational criminal livelihood.3) The lives of human traffickers both during and after imprisonment and their navigation of legal and illegal work domains.This knowledge will not only be beneficial for the academic research commun
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'European Consortium for Microbial Resource Centres' (EMBARC) under Seventh Framework.

assistant: **Objectives**

EMbaRC will establish a self-sustainable community of European Microbial Resource Centres representing a large bio-diversity and offering a wide-range of not only bio-resources but also expert services. These services will enable the development of new partnerships with public institutes in the field of biodiversity and will facilitate revenue-generating partnerships with the economic sector (large food or biotech companies, research organisations, SMEs, NGO’s etc) that will be defined in a set of validate business models for Biological Resource Centres. The objective is to enable not only the EMbaRC partners but also other European BRCs, especially those who are endangered or isolated, to find complementary sources of funding to ensure their future existence. Thus EMbaRC proposes an extensive training and outreach programme targeting these collections as well as the wider research community. Furthermore providing access to the partners’ expert services via the transnational access proposed will enable EMbaRC to improve, coordinate and validate its offer to the research community from within both public and private sectors. Through its networking and harmonisation activities EMbaRC will lay down the foundations of the future Global Biological Resource Centre Network ensuring that European expertise and research are at the forefront of the International scene. Through the EMbaRC joint research programme the partners will pool their resources and expertise to collaboratively improve strain and DNA storage and develop new identification methods for microorganisms for the benefit of the wider scientific community.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Translational implications of the discovery of brain-draining lymphatics'.

assistant: **Concept**

In 2010, 800 billion Euros was spent on brain diseases in Europe and the cost is expected to increase due to the aging population. – Here I propose to exploit our new discovery for research to alleviate this disease burden. In work selected by Nature Medicine among the top 10 ”Notable Advances” and by Science as one of the 10 ”Breakthroughs of the year” 2015, we discovered a meningeal lymphatic vascular system that serves brain homeostasis. We want to reassess current concepts about cerebrovascular dynamics, fluid drainage and cellular trafficking in physiological conditions, in Alzheimer’s disease mouse models and in human postmortem tissues. First, we will study the development and properties of meningeal lymphatics and how they are sustained during aging. We then want to analyse the clearance of macromolecules and protein aggregates in Alzheimer’s disease in mice that lack the newly discovered meningeal lymphatic drainage system. We will study if growth factor-mediated expansion of lymphatic vessels alleviates the parenchymal accumulation of neurotoxic amyloid beta and pathogenesis of Alzheimer’s disease and brain damage after traumatic brain injury. We will further analyse the role of lymphangiogenic growth factors and lymphatic vessels in brain solute clearance, immune cell trafficking and in a mouse model of multiple sclerosis. The meningeal lymphatics could be involved in a number of neurodegenerative and neuroinflammatory diseases of considerable human and socioeconomic burden. Several of our previous concepts have already been translated to clinical development and we aim to develop proof-of-principle therapeutic concepts in this project. I feel that we are just now in a unique position to advance frontline European translational biomedical research in this sud
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'IMPACT OF AGENTS WITH POTENTIAL USE IN FUNCTIONAL FOODS ON BIOMARKERS FOR INDUCTION OF AGE RELATED DISEASES' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

A number of epidemiological studies have consistently demonstrated the protective effects of fruits and vegetables with respect to several age related diseases. The aim of this project is to investigate the protective action of agents with potential use as functional food constituents with respect to cancer, diabetes and cardiovascular disease. In collaboration between EU and Indian research centers the proposal features a multipronged approach, where the protective action of various non-toxic agents are studied in vitro as well as in rodent models with respect to induction of DNA lesions, tumours and biomarkers for the development of diabetes, diabetic retinopathy and atherosclerosis. In addition, reduced availability of carcinogens and inhibition of their metabolic activation are investigated. Testing of the protective efficacy of functional food components in intervention cross-over studies in humans exposed to carcinogens, that are normally present at significant levels in the environment, represents an approach that has rarely been resorted to, and will be implemented under this project in Europe as well as in India using sophisticated molecular, cytogenetic and other analytical methods. Although there has been remarkable progress in our understanding of the processes that lead to neoplasia and diabetes, the mechanisms underlying chemoprevention are, in general, little understood. The results from this project are expected to provide an improved insight with respect to this topic.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'From Oscillations to Outflows: Taking Black Hole Accretion to the Luminous Limit' (FOOTBALL).

assistant: **Innovation**

Accretion onto black holes produces some of the most spectacular phenomena in the Universe, and provides an unparalleled laboratory for studying strong field gravity. Intensive monitoring of black holes over 8 decades in mass has established a rich data set with which to test accretion theory and probe strong gravity. At the same time, black hole accretion theory has made rapid progress in the last several years due to the development of realistic numerical simulations. Despite these advances, there is still a missing link between numerical simulations and observations of luminous black holes. This proposal aims to connect contemporary accretion and jet theory with observations of powerful outflows and quasi-periodic oscillations in accreting black hole systems.First, I will develop an accretion disc model for the most luminous states of stellar mass black holes, including their high frequency quasi-periodic oscillations, motivated by simulations. I will test the model through spectral fitting and timing analysis, and use it to make the first robust black hole spin estimates from observed QPOs. Second, I propose to study a large-scale magnetic reconnection mechanism for driving black hole state transitions and transient outflows. I will calculate images, light curves, and spectra from these outflows. Comparing the results to observations will test MHD jet formation theory and help to unify accreting black holes across the mass scale.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'NGOs, Transnational Networks and the Transformation of Muslim Communities in Cambodia' (TRANSCAMUS).

assistant: **Concept**

Since the 1993 reinstallment of the monarchy after the devastating rule of the Khmer Rouge and the subsequent Vietnamese occupation, foreign NGOs have been mushrooming in Cambodia. Several among these are charities that are based in Malaysia and the Arabian Gulf, and which have become the core of Muslim transnational networks that intersect in the country. These charities invested vast resources in order to reconstruct the Cambodian Muslim religious infrastructure and leadership, that had been almost completely wiped out during the Khmer Rouge. At the same time, they spread their own religious ideas and discourses among the country’s Muslim minorities. This research will inquire into how transnational Muslim networks and charities based in the Middle East and Malaysia have transformed the religious identity, leadership and infrastructure of Cambodia’s Muslim minorities. I will look into the evolution of the Gulf and Malaysian charities in the country, the patterns of the existing competition between them, and how the transnational flows and the transformation of the Islamic field altered the structure of gender relations among Cambodian Muslims. The chief method of data collection will be ethnographic fieldwork conducted in Cambodia, Malaysia and Kuwait.