RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Studying the Mechanisms of Enhanced Pathogenesisin Polymicrobial Respiratory Co-Infection' (ReCoIn), addressing dissemination and exploitation.

assistant: **Impact**

Illness caused by respiratory infection with Influenza viruses represents a vast healthcare and economic burden in the modern world. It is well established that respiratory viral infections are often complicated by secondary bacterial infections, however co-infection often causes a much more severe disease than either microorganism would individually. The mechanisms behind this synergy are not fully understood, however adhesion; the first step in bacterial colonisation, has been shown to be enhanced in virus-infected cells. We hypothesise that early events following Influenza infection of lung epithelium promote bacterial adhesion by regulating primary receptor trafficking and may offer new targets for anti-bacterial intervention.The aims of this project are to dynamically characterise the adhesion of individual bacteria to airway epithelial cells with high-temporal and spatial resolution and to study the effects of Influenza A co-infection on this phenomenon. We will develop new protocols to track bacteria in three dimensions in order to study individual adhesion events and will calculate diffusion modes during and after bacterial contact with the host cells. These studies will provide novel insights into the processes underlying bacterial adhesion and will explore the mechanism of viral-bacterial synergy to discover new targets for the prevention and treatment of serious respiratory infections.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Strengthening European research cooperation for smart and sustainable management of tropical and subtropical biodiversity in outermost regions and overseas countries and territories' under Seventh Framework.

assistant: **Concept**

NetBiome-CSA will extend and strengthen research partnerships and cooperation for smart and sustainable management of tropical and subtropical biodiversity in outermost regions (ORs) and overseas countries and territories (OCTs). This will be achieved through a participative process mobilising stakeholders, their knowledge and resources for initiatives such as policy and priority analysis, multi-stakeholder dialogues, exchange of good practices, training and issuing of recommendations.The project builds on the existing biodiversity research partnership created through the ERA-Net project NetBiome and takes on the challenge of mobilizing further stakeholders at all levels of the quadruple helix (knowledge institutions, enterprises, government and civil society) to address perceived priority challenges in conciliating conservation and sustainable management of tropical biodiversity with the sustainable development of Europe’s regions and territories, based on the benefits from high biodiversity.The project’s activities, specifically tailored to the needs and priorities identified by the ORs and OCTs, will contribute to: improved research and innovation governance; alignment of research efforts with policy needs strengthening evidence-based policies; enhanced implementation and impact of the EU Biodiversity Strategy and CBD Strategic Plan; innovative biodiversity management tools (Biodiversity Management Toolbox), increased regional socio-economic and cultural development; enhanced international visibility of ORs and OCTs and the uptake of their good practices, expertise and knowledge; effective international and trans-regional cooperation among European ORs and OCTs and with third countries.NetBiome-CSA fully addresses the topic (ENV.2013.6.5-2) and subtopic (g) of the wo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Resilient Cultures – Music, Art, and Cinema in Mainland China and Hong Kong' under Horizon Europe.

assistant: **Concept**

How to be critical in a context where critique is disavowed? How to speak against power while being silenced? How to stay amidst suppression? RESCUE studies how cultural practices in the domains of popular music, contemporary art, and queer cinema, in mainland China and Hong Kong, develop resilient tactics to express their social and political discontent. It theorises resilience and cultural critique in times of intensified authoritarianism and rapid platformization. Whereas such practices can resort to a history of experiences in China to negotiate a recently intensified authoritarianism, cultural practitioners in Hong Kong are facing a compressed authoritarianism  still searching for resilient tactics.RESCUE studies indie music in Hong Kong; folk music in China; the role of official and unofficial art institutes in China and Hong Kong; socially engaged art projects in rural and urban areas in China and Hong Kong; and queer cinema and queer film festivals in China and Hong Kong. It develops a relational comparative analysis between different cultural fields, and at different localities (Hong Kong, Beijing, Shanghai, Guangzhou, Tianshui), to unpack the (im)possibilities of critique. RESCUE develops an innovative methodological toolkit, combining ethnography with textual analysis, digital methods, and collaborative research. RESCUE will establish and consolidate a network of academics, cultural practitioners, and activists in mainland China, Hong Kong, East Asia, and Europe, through multiple workshops, a podcast series, performances, screenings, and an exhibition  thereby increasing the social impact of the project. Findings will not only attest to the multivocality, diversity, and vitality of cultural production in mainland China and Hong Kong, thus pushing back against
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Coordination of the European Future Internet forum of Member States' in the context of a Seventh Framework call.

assistant: **Objectives**

The limitations of the present Internet require global investment to develop a Future Internet (FI) capable of meeting the unprecedented demands of the Knowledge Society. It is strategically important for Europe to engage fully in the conception, research, development and innovation of the FI. Other regions recognise the potential of the FI and have launched major initiatives, such as NetSE  (US), AKARI  (Japan) and AsiaFI  (East Asia), targeting novel Internet architectures and the Network of the Future.<br/>Europe is already one of the leaders in Internet research and adoption and wishes to lead the definition, standardisation and implementation of the FI. However Europe will achieve its FI potential only if there is good coordination of FI research activity across Member State (MS), regional and transnational levels.  Otherwise, duplication of effort reduces net output and value for money across all FI programmes, and the full benefits of networking between EU-funded and national researchers are not realised, fragmenting the original research objectives and achievements. The EC already informally hosts the Future Internet  Forum (FIF) at FI Assembly meetings. ceFIMS (Coordination of the Future Internet Forum  of Member States) will provide functional ongoing support to the FIF to create synergies between research programmes funded by the Member States and promote outreach to similar EC-funded research.<br/>In the short term, ceFIMS will facilitate FIF activity by providing a Secretariat and support structures and by establishing the ceFIMS FI portal. In the medium term, it will foster knowledge sharing via the FI Forum, the establishment of expert working groups and the development of a Research Roadmap on behalf of the Forum. In the longer term ceFIMS will create a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Cultural Narratives of Crisis and Renewal'.

assistant: **Concept**

The objective of the “Cultural Narratives of Crisis and Renewal” project is to examine cultural production and cultural practices in periods of societal crisis at the turn-of the 20th Century on both sides of the Atlantic. The overarching aim of the project is to investigate the role of cultural production, not just as a vehicle to elaborate cohesive narratives in moments of crisis, but as a space to create alternative imaginaries for social renewal. We need to explore the changing nature of our societies and the reconfiguration of regional and/or national cultural landscapes into globalized real (and virtual) spaces that erode the cultural frontiers of the nation-state.The project aims to address the scarcity of scientific research on cultural narratives elaborated around conjunctures of crisis and renewal, from the 1970s transition to neoliberalism in Latin America, to the aftermath of the 2008 financial crisis in Spain. The analysis of cultural narratives and production in periods of societal crisis will lead us to identify underlying sets of values, beliefs, and practices: the way people think and act; who those people are and why they operate in a given cultural set (Cardoso and Jacobetty 2012). The programme will bring together researchers specialized in Hispanic and Latin American culture from 4 universities in Europe (Newcastle University (UNEW), Amsterdam University (UVA), Universitat de València (UV) and Universitat de Lleida (UDL)) and 4 universities in Latin America (Universidad Austral de Chile (UACH), Pontificia Universidad Católica del Perú (PUCP), Universidad Nacional de Córdoba (UNC: Argentina), and Universidad Nacional Tres de Febrero (UNTREF: Argentina)). The project will support international networking, high quality academic publications (including
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Startup Europe Partnership 2.0' (2014-2020).

assistant: **Concept**

SEP 2.0 aims at supporting European scaleups ‘go to market’ by providing qualified opportunities. Specifically, the Consortium plans to address three specific areas:- Increase exits and support promising European tech scaleups to access IPO opportunities.- Match established companies with scaleups to generate revenue and enable commercial opportunities.- Expose to the international community of investors via reports, roadshows, and participations in international events.The Consortium will regularly scout and filter the most promising tech scaleups across Europe. The scaleups will be engaged in a set of activities that match their priorities and increase their access to new customers, the distribution of new products or services on the market, and increase the turnover. In order to engage the different stakeholders of the project (namely: scaleups, investors, and corporates) the Consortium aims at organizing 4 Scaleup Summit per year hosted by the main European stock exchanges. Selected scaleups will be invited to each event, together with a group of corporates and investors. The goals of the Scaleup Summit are listed below: - To prepare tech scaleups for opportunities such as exit and going public (IPO). - To increase strategic and commercial opportunities for scaleups by organizing business meetings with corporates.- To facilitate the access to finance for scaleups by organizing meetings and pitching with investors.- To help EU and international investors to gather and improve knowledge of investment opportunities.- To provide networking opportunities for corporates.Following the Scaleup Summit, a selected group of scaleups will enroll into programs to increase the chance of successful IPOs. Scaleups will be continuously assessed and engaged with new opportunities.Fin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Challenging Hypertension Through Novel Medical Device Development' (REALTA).

assistant: **Innovation**

Hypertension directly causes approximately 25% of heart attacks in Europe and, in its progressed form of cardiovascular disease, it is estimated to cause 42% of all deaths across Europe annually. Untreated hypertension is one of the primary contributors to a number of the medical conditions with the greatest burden of care, including stroke, dementia and kidney failure. One of the most promising avenues for the treatment of hypertension has been research into primary aldosteronism (PA). In the last ten years, PA has been recognised as the most common curable cause of hypertension. PA is thought to account for up to 18% of all cases of hypertension within the population and is caused by benign shallow adenomas on the surface of the adrenal gland. Researchers have identified the effective treatment of PA as a clear mechanism to address Europe’s hypertension problem. However, finding an effective surgical or pharmaceutical treatment for PA has been challenging to date.  Radiofrequency ablation (RFA) has also been evaluated for the treatment of adrenal cancer . RFA involves the insertion of an ablation needle into adrenal adenoma and passing high frequency electrical current into the gland. The weakness of RFA is that it produces a large ablation zone, which is particular problematic in a small organ typically less than 5cm3 in volume.  In many cases, a large proportion of the functional cortex tissue surrounding the adenoma can be destroyed during the RFA process , thereby negating the benefit of the RFA over the traditional adrenalectomy approach. An ideal ablation technology would involve a custom-designed microwave ablation device capable of destroying the shallow adrenal adenoma, while simultaneously protecting the delicate tissue of the remaining gland. That is precis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Aiding the Neglected: Meta-Analysis of Emotional Maltreatment Prevention and Intervention Programs' (2007-2013) targeting Seventh Framework.

assistant: **Abstract**

Emotional maltreatment has been called the most elusive and damaging of all types of maltreatment for a child, and represents the core issue and most destructive factor across all types of child abuse and neglect. This characteristic of negative parent-child relationship has recently received scientific attention with acknowledgments that such neglect the most frequent forms of maltreatment experienced by children and adolescents and has detrimental mental health consequences. With attention given to employment of evidence-based programs as programs with proven effectiveness, examining the effectiveness of various programs for emotional maltreatment is of high theoretical and practical importance. Programs that target other forms of child maltreatment have been subject to several meta-analyses. However, the effectiveness of programs for emotional maltreatment has not been examined under the lens of meta-analysis, and are thus still under much debate. Implementation of meta-analysis in this stage of saturated research on the emotional maltreatment is a crucial step in the further understanding of this phenomenon, and will enable concluding imperative theoretical and practical implications. Thus, the objective of the proposed research project is to conduct a meta-analysis of the effectiveness of identification, prevention and intervention programs for emotionally maltreated children. Beyond its practical implications (e.g., pointing to identification and treatment programs that are evidence-based), the proposed research may offer a theoretical contribution, heretofore unapplied, to the understanding of parental practices that have the most crucial impact on the child’s holistic well-being: mental and physical. This study will be conducted in the Berkeley School of Public
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Dissecting the chromatin response to DNA damage in silenced heterochromatin regions' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Cells are continuously exposed to insults that can break or chemically modify their DNA. To protect the DNA, cells have acquired an arsenal of repair mechanisms. Proper repair of DNA damage is essential for organismal viability and disease prevention. What is often overlooked is the fact that the eukaryotic nucleus contains many different chromatin domains that can each influence the dynamic response to DNA damage. Different chromatin environments are defined by specific molecular and biophysical properties, which could necessitate distinct chromatin responses to ensure safe DNA damage repair.The aim of this proposal is to understand how diverse chromatin domains, and in particular the dense heterochromatin environment, shape the dynamic chromatin response to DNA damage. I recently developed locus-specific DNA damage systems that allow for in-depth analysis of chromatin domain-specific repair responses in Drosophila tissue. I will employ these systems and develop new ones to directly observe heterochromatin-specific dynamics and repair responses. I will combine these systems and state-of-the art chromatin analysis with high-resolution live imaging to dissect the DNA damage-associated heterochromatin changes to determine their function in repair -kinetics, -dynamics and -pathway choice.Deciphering the chromatin dynamics that regulate DNA damage repair in heterochromatin will have broad conceptual implications for understanding the role of these dynamics in other essential nuclear processes, such as replication and transcription. More importantly, understanding how chromatin proteins promote repair will be important in determining how cancer-associated mutations in these chromatin proteins impact genetic instability in tumours in the long run.


**Keywords:** Heterochroma
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Precision and accuracy of tools in recruitment studies' under Fourth Framework.

assistant: **Concept**

The proposal deals with precision and accuracy issues in two categories of measurements which together encompass most of the data which are routinely required from samples of early life stages of fish:1) the growth and condition of individuals.2) the origin of individuals.Quantitative evaluation of the growth rate and condition of larvae in relation to environmental conditions at the time of capture is an essential pre-requisite to predictive assessment of survival potential. In particular, the identification of starving or sub-optimally growing larvae in the population is a powerful method for evaluating survival probability. Both biochemical and otolith microstructure methodologies offer the prospect of identifying individuals at risk. However, understanding of the underlying physiology of somatic and otolith growth and development is not sufficiently advanced to allow a high degree of accuracy. In particular, decoupling of otolith and somatic growth under some circumstances is recognised but not understood, whilst the precise roles of body size, feeding rate and temperature on the biochemical condition index of RNA/DNA is not known. The aim of this project is to investigate the physiology of growth and development in larvae by a series of controlled laboratory and mesocosm studies, in order to improve the understanding of the growth processes and increase the accuracy of condition and survival predictions from biochemical and otolith microstructure measurements. Determining the origin of early-life stages is important for a number of applications. Origin in this context refers to the timing and location at which a specimen was hatched, and the history of an individuals' growth rate and environment between hatching and capture. For example, the date and temperature of