RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Theory and applications of subtyping systems for proof development, programming, and interactive processes'.

assistant: **Concept**

I propose to study subtyping, a primitive relation important to many different areas of computer science, including software specification, object-oriented programming, modular software design, and computer-assisted proof. My first research goal is to study subtyping systems for programming languages. Sustained research over the last decade has led recently to powerful new type systems for a broad range of object-oriented features. MY research will have applications to Standard ML1S successor ML2000 and to object calculi. My second research goal is to provide a theoretical basis for enriching proof-checking systems with subtyping. Existing proof checkers, such as LEGO, COQ, and ALF do not incorporate subtyping because we do not understand the interaction between subtyping and dependent types. I propose to study this interaction in a type system incorporating these two features. My third research goal is to investigate the applications of typing and subtyping in concurrency.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Clinical trial of autologous adipose-derived mesenchymal stromal cells (ASC) in the treatment of mild to moderate osteoarthritis' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Osteoarthritis (OA) is an incurable disease that has evaded pharmacological interference, biologic therapy or surgical intervention to prevent disease progression. Currently, OA is designated the 11th highest contributor (of 291 diseases) of global disability. In the absence of effective treatment options, cellular therapies using mesenchymal stem/stromal cells (MSCs) have emerged as potential candidates to overcome this clinical short-coming.  Autologous adipose-derived mesenchymal stromal cells (ASCs) are attractive for cellular therapy given the abundance of tissue, high frequency of MSCs and minimally invasive harvest procedure. The EU consortium ADIPOA has shown in a ‘first in man’ 2-centre Phase I safety study that intraarticular injection of a single dose of autologous ASCs to the knee (18 patients, 12 month follow-up) was well-tolerated, had no adverse effects, and resulted in an improvement in pain score and functional outcome. ADIPOA2 will deliver a large-scale clinical trial in regenerative medicine for OA.  The purpose of the project is to design and implement a phase IIb study to assess the safety and efficacy of autologous (patient-derived) ACSs in the treatment of advanced OA of the knee.  The cells will be prepared from samples of adipose tissue harvested from patients by lipoaspiration.  ADIPOA2 will comprise a multi-centre, randomized clinical trial comparing culture-expanded, autologous adult ASCs in subjects with knee OA with another widely used therapeutic approach for knee degeneration (injection of Hyaluronan).  There are two large elements of the study: (1) the production of consistent batches of high-quality autologous ASCs under GMP-compliant conditions and (2) delivery of these cell doses to patients in a trial which will meet all national and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'GOT ENERGY TALENT. Attracting Talented Researchers within the Spanish Campus of International Excellence ‘Smart Energy’ and the region of Madrid.' in the context of a Horizon 2020 call.

assistant: **Objectives**

GOT ENERGY TALENT is a highly competitive, merit-based fellowship programme aimed at incorporating postdoctoral talent on the area of SMART ENERGY to enable them to conduct their own excellent research project and bringing it closer to the society, in order to produce a positive effect not only in terms of excellent science and talent attraction but also by strengthening the regional economy and promoting international networking.GOT ENERGY TALENT will bring in 34 experienced researchers to develop a 24-month stay through 2 open calls at international level (17 fellowships per call), over its 60 months of implementation. The postdoctoral fellows will have a full trans-national mobility experience and access to the research facilities of the organisations partnering the programme from and outside academia. The fellows will freely decide whether to carry out a 24-month advanced research project or a 12-month advanced research combined with a 12-month period devoted to applied research, in one of the hosting institutions within the network of internationally recognised organisations on this core area.GOT ENERGY TALENT will strengthen a favourable environment in order to attract talented and experienced researchers by offering an attractive ecosystem, composed of academic and industrial organisations focused on ENERGY AREA with a strong potential. The selection of the area is based on the objectives posed by the Research and Innovation Strategies for Smart Specialisation (RIS3) of the region of Madrid, which encompasses Energy, amongst other prioritised areas, along with the long-term vision of the Universidad de Alcalá and the Universidad Rey Juan Carlos, as it is clear from their involvement in the CIE ‘Smart Energy’ focusing on Bioenergy and Smart Cities. Furthermore, GO
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Discovery and validation of ‘epidrivers’ of cancer evolution and resistance to therapy' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Intra-tumoral heterogeneity allows all form of cancers to undergo an evolutionary process in response to selective pressures, such as therapy, which results in a more aggressive disease. As chronic lymphocytic leukemia (CLL) are particularly amenable to evolutionary investigations, it has been shown that CLL’s capacity to escape therapy is linked in to genetic evolution, which is fueled by intra-tumoral heterogeneity. Aberrant DNA methylation can also dysregulates genes involved in CLL pathogenesis. Like genetic alterations, DNA methylation modifications are heritable and subject to natural selection. Landau et al have studied sub-population DNA methylation heterogeneity in CLL and uncovered a large amount of stochastic variation. The acquisition of stochastic DNA methylation alterations enhances epigenetic plasticity and creates a non–genetically encoded source of heterogeneity, fuelling tumour cells in their search for superior evolutionary trajectories. These new data modify the way we understand cancer epigenetics, and offer a new field of investigation: identify “epidrivers”, i.e. somatic epigenetic alterations leading to cancer-heterogeneity and which are positively selected through cancer evolution.   Thus, I will pursue in this project four independent yet complementary aims. During my outgoing period I will robustly identify epidrivers from bulk next-generation sequencing (NGS) (Aim 1) and from single-cell NGS (Aim 2) of a large CLL cohort. Candidate epidrivers uncovered from the first two aims, will be further validated in a large-scale epigenome editing screen (Aim 3). Then building upon technological development from Aim 2 and 3, during my returning period at Curie Institute, I will extend this important paradigm to solid tumor by exploring breast cancer evo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Novel steps in assessing the impact of EU Framework Programmes on European scientific networks', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

In an effort to boost industrial competitiveness and address societal challenges through excellence research, the European Framework Programmes (FPs) have been concentrating resources in a core of top-performing research institutions. But pursuing excellence at the expense of cohesion is a risky endeavour, as it can exacerbate inter-regional economic disparities. FPrevision4cohesion aims to unravel the impact of competitive FP research funding and different policy designs on the structural and spatial dynamics of the European scientific network. Developing a comprehensive picture of FPs’ influence on knowledge distribution and inequality is critically needed if we are to avoid deepening existing innovation divides and guide cohesion efforts in a targeted way. If convergence is understood not as mere redistribution of funds from core to peripheral regions, but as sustained support for the periphery's research and innovation capacity, we need deeper insights into the FPs' role in consolidating or fragmenting collaborative core-periphery ties.The project will adopt a novel counterfactual analysis, comparing for the first time the impact of funded to non-funded FP projects using network science techniques. This approach offers significant advancements over existing studies which rely almost exclusively on funded FP collaborations and are therefore limited in their capacity to isolate causal effects. The analysis is meant to not merely quantify impact, but also highlight how the structural links between core and peripheral organisations could be strengthened, and how different policy instruments with a top-down vs bottom-up intervention logic influence the process. FPrevision4cohesion aspires to guide both research and policy in balancing competitive programmes with converge
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Catalytic reductive carboxylation of unactivated olefins with carbon dioxide'.

assistant: **Concept**

Carboxylic acids are building blocks of utmost importance in our chemical industry, as these motifs are extensively used in the manufacture of soaps, detergents, pharmaceuticals, rubber, plastics, dyes, textile, perfumes, and animal feed, among many others. Current industrial protocols for their synthesis rely heavily on toxic reagents, lengthy-step pathways or waste-producing procedures such as hydrolysis of nitriles or two-step techniques based on hydroformylation of olefins with highly toxic carbon monoxide with expensive noble catalysts (Rh) followed by oxidation. Unlike hydroformylation methods, OLE-DIOX offers the opportunity of promoting a carboxylation event using unactivated olefins, products produced in bulk from petroleum processing, with abundant carbon dioxide as C1 source. The protocol is user-friendly, with components that are neither air- nor moisture sensitive, utilizes earth-abundant catalysts and operates under mild conditions. OLE-DIOX represents an important contribution for our circular economy by effectively recycling bulk materials into valuable products in one-step operation. These unique features makes OLE-DIOX technically and economically viable for its implementation at large-scale en route to industrially-valuable carboxylic acids, thus avoiding lengthy and waste-producing protocols in the established oil-to-carboxylic acid process chain.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Intermediate temperature catalytic methane splitting for a swift energy decarbonization' (ZeroCarb), addressing dissemination and exploitation.

assistant: **Impact**

Project ZeroCarb will develop, optimize, and operate an intermediate-temperature catalytic methane splitting (IT-CMS) reactor, with the balance of plant, in a relevant environment (TRL6), using biomethane as feedstock and green electricity. This project follows 112CO2 (GA 952219), which developed the fundamentals for the IT-CMS. It is generally accepted that this reaction, also known as methane decomposition or pyrolysis, will play a critical role in the swift and cost-effective energy transition. Due to this great potential, several different processes have been proposed, and new and existing companies are investing in this technology. IT-CMS technology displays, however, critical advantages over all other technologies: i) avoids the use of special reactor’s envelop materials, since it runs at 750 °C and 1 bar, and is catalytic; ii) when fed with biomethane it produces H2 with a negative CO2 footprint and renewable graphitic carbon; iii) the produced metal-free carbon nanofilaments (mostly MWCNT) are shaved off chemically using H2; iv) the reactor is more energy efficient since it uses a fixed bed; v) the catalyst is activated steel foil, commercially available, which reduces the CAPEX tremendously; vi) the reactor module is expected to display a high power density, ca. 1.5 kW L-1, and energy efficiency > 80 %, and a catalyst high stability >> 8500 h; and vii) low CAPEX plant, significantly cheaper than an SMR plant.ZeroCarb targets the development of a demonstration unit producing 2 kgH2 h-1 (ca. 67 kWH2e) and 6 kgC h-1, based on an activated steel foil packed in a plate and frame module. HyCarb aims to bring this technology into the market and meet industry standards or regulations. The business model will be validated with the two industrial partners, CapWatt for hy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Liquefied gas injection technology to increase efficiency and control of in-situ soil remediation techniques'.

assistant: **Objectives**

Past and present human activities which introduce contaminants to the soil and groundwater have resulted in some 750,000 sites across Europe with suspected co ntamination. A clear need exists to remediate these sites through effective and timely solutions at a viable cost to society. This project focuses on soft soils with contamination 10 20 m below the land surface. Preferably, in situ techniques are applied to decontaminate these sites. The alternatives, ex situ treatment or containment, are too expensive or socially an improper solution. H owever, the low soil permeability often limits application of in situ technique s. In situ techniques can be enhanced by improving this permeability for instan ce through soil fracturing. Fracturing can be induced by injection of gas or li quids into the contaminated area. Cost effective soil fracturing techniques using gas were already developed in the USA, but are not exploited in the E.U. This proposal describes a workprogramme to develop a prototype for a new type o f fracturing system: the LIQIT technique. LIQIT will introduce soil fracturing in the E.U. and will use liquefed gas. This will improve results from existing fracturing techniques. The objective of a Danish German Dutch Belgium consor tium of SMEs is to develop the LIQIT process. A prototype LIQIT process will be constructed and extensively tested in field tests. Development will be based o n demands and constraints from in situ techniques that could be enhanced by LIQ IT. The consortium combines know how on injection of liquid gas with core busin esses in preparing and executing in situ soil remediation projects. The consort ium is supported by two large Dutch organizations involved in soil remediation. Contract research is performed by a Danish Dutch combination
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Visible Light Communication (VLC) application for mobile devices as control access, validation, master key or secure payment solution.' in the context of a Horizon 2020 call.

assistant: **Objectives**

LightBee S.L. innovated the solution which uses LEDs installed in any transmitter to transmit binary codes by means of light modulation to an optical receiver which later decodes the light flash. The light is transmitted at a very high speed to avoid the possibility to distinguish values by video camera or human eye. It allows auto check-in and access control to private property or office only with the mobile information. The LightKey product based on Visible Light Communication (VLC) is very powerful and at the same time low cost technology, that can be adapted to grant safe access permission by using merely mobile device with the performance similar to intrusive and expensive NFC and RFID technologies. The set consists of Control Unit, Optical Receiver, mobile application and uses standard electronic lock. As there is an increasingly urgent need for authenticated entrance and the universal integration of mobile devices in our society is observed, LightKey has the chance to meet the broad range of innovative customers of the Access Control Market: private companies and independent users (hotels, complexes, condominiums, car makers) and public customers where security is a top priority (hospitals, banks, administration). When considering further proliferation of solid-state lighting (SSL), LED importance, the fact that nowadays technologies: NFC, Bluetooth, WIFI are subject of security problems related to data transmissions and moreover the increasing crime rate related to domestic burglary worldwide, VLC can become the most promising technology in terms of commercial viability. A full assessment of customer needs and the elaboration of a realistic business plan with in depth market feasibility study is the main objective of present Phase 1. After positive output follow
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Electro-agglomeration and separation of Engineered NanoParticles from  process and waste water  in the coating  industry to minimise  health and environmental risks' (NANOFLOC).

assistant: **Concept**

The rapid introduction of nano-based products into the market has caused a major concern both for health and environmental impacts, among others from the paint and coating business. A number of studies have documented health risks related to nanoparticles, inhalation exposure and dermal contact being main exposure routes in the coating and paint industry. Likewise, discharge of nanoparticles into aquatic environment causes damage to the gill membrane of fish and crustaceans. Today, the only effective means of removing nano-particles from water is application of energy intensive methods such as reverse osmosis.  Therefore, the coating industry that uses products with nanoparticles needs a cost effective technology for removing them from used water.The proposers of NANOFLOC have thus identified a new market opportunity in developing a novel electro agglomeration technology for removing nanoparticles  entrained in water. The technology is cost effective, compact and nvironmentally friendly. It is based on destabilisation of nano suspensions and agglomeration of charged particles in solutions using electric fields and flocculation in one step, avoiding addition of chemicals. The objectives of NANOFLOC will be attained by development of innovative reactor for agglomeration and stabilisation of flocs, superior hydraulic design of a reaction chamber and creation of intelligent process control system (PCU).The RTD work is structured in 5 of 8 WPs: In WP1, a life cycle analysis will be undertaken to provide a benchmark for  the development program. Scientific characterisations of the process and development of parameters will be performed in WP2. Design and configuration development of the reactor will be carried in WP3. The PCU will be developed in WP4. The NANOFLOC system will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Modalities in Substructural Logics: Theory, Methods and Applications' (MOSAIC).

assistant: **Innovation**

Modal logics are a family of formal systems based on classical logic which aim at improving the expressive power of the classical calculus allowing to reason about “modes of truth”. The aim of the present proposal is to put forward a systematic study of substructural modal logics, understood as those modal logics in which the modal operators are based upon the general ground of substructural logics, weaker deductive systems than classical logic. Our aim is also to explore the applications of substructural modal logics outside the bounds of mathematical logic and, in particular, in the areas of knowledge representation; legal reasoning; data privacy and security; logical analysis of natural language.


**Keywords:** Modal logics,  Substructural logics,  Proof theory,  Residuated Lattices,  Kripke Semantics,  Duality Theory,  Coalgebras,  Applied logic,  Computational linguistics