RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Metabolic adaptation in injuries of the peripheral nervous system' (NERVADAPT), addressing dissemination and exploitation.

assistant: **Impact**

The peripheral nervous system constitutes a prime example of a tissue with a strong regenerative potential. Full recovery upon nerve trauma, however, is rare and usually fails in peripheral neuropathies - common, yet largely untreatable neurological disorders. Nerve repair strictly depends on the orchestration of both nerve de- and regeneration by peripheral nerve glial cells, which need to overcome a substantial metabolic challenge in injury. NervAdapt is based on the fundamental premise that Schwann cells, in the course of evolution, developed an exceptional metabolic adaptability to ensure repair. Capitalizing on acute nerve injury as a prototypic model system to explore conserved repair mechanisms, we aim to unveil glial metabolic adaptation to increased energetic demands and distinct substrate availabilities. A central goal of NervAdapt is to elucidate how glial homeostasis is integrated in a fine-tuned cellular network that extends to interactions with neighbouring tissue compartments. Employing elaborated genetic mouse models, 3D electron microscopy, and leading-edge spatial and single cell to organ level profiling approaches, NervAdapt will pioneer to generate a comprehensive multi-level framework of the nerve injury response. Chronic metabolic stressors, such as in diabetes and obesity, in turn, may lead to a constant glial overstimulation and compromise glial metabolic homeostasis. Metabolically induced neuropathies indeed underscore the specific vulnerability of the peripheral nervous system to a systemic metabolic burden. Within NervAdapt we follow the hypothesis that a persistently perturbed metabolic homeostasis causes molecular and cellular glial metabolic inflexibility, ultimately driving metabolic neuropathy. Together, NervAdapt seeks to identify key ch
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Health effects of UVB exposure with special emphasis on infectious in man.' to be submitted under Fourth Framework.

assistant: **Abstract**

The objectives of the present proposal are to study the relationship between dose, wavelength and duration of UVB exposure and the effect on resistance to infections. The proposed studies will further advance knowledge with respect to mechanisms controlling adaptation, immunological tolerance and susceptibility of humans and animals. This information is necessary to improve the risk estimation for effects of UVB on the resistances to infections. Using mathematical models describing relationships between different parameters of the immune system and resistance to infections, animal data will be extrapolated to the human situation. The project will also investigate whether available epidemiological data on relevant infections in man are suitable for validation of the mathematically calculated (extrapolated) data.* Immune system  The target cells, i.e. keratinocytes, LCs, fibroblasts, T cells, mast cells, NK cells, PMNLs will be studied with  respect to UV-effects in different species. The effects, i.e. altered release or production of mediators or altered  expression of surface markers will be studied. Both in vivo and in vitro exposure experiments are necessary.  Additionally, the role of urocanic acid (UCA) and DNA will be examined with respect to their roles as initiators  of UVB-induced immunosuppression.  * Infections  1. Skin-associated infections. Responsible triggers for recurrent herpes simplex (HSV) infections in man and  animal will be further analyzed: both genotoxic and immunotoxic phenomena may play a role. Tools to analyse  these triggers are in vivo and ex vivo/in vitro specific immune responses to the pathogen in animals and man.  For special purposes, transgenic animal models will be used (i.e. cytokine deficient, DNA repair deficient, UCA  deficient). I
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Empowering innovation intermediaries to generate sustainable initiatives to incentivise and accelerate the commercialisation of space innovation' (InnORBIT), addressing dissemination and exploitation.

assistant: **Impact**

InnORBIT will support 50 start-ups and scale-ups to grow and commercialise their space solutions via 20 sustainable and effective initiatives. We focus on SEE and CEE countries with vibrant tech ecosystems and industry verticals with great potential for contributing to the commercialisation of space. We anchor our initiatives to innovation intermediaries well-embedded in their ecosystems, starting with a pivotal space technology and industry association in Romania, an intermediary managing 3 high-tech clusters in Greece and a major digital innovation hub in Croatia. Alongside them we co-develop our solutions: a business support programme to help space entrepreneurs in starting and scaling-up their commercial activities and a capacity building programme for training intermediaries to set up and run local initiatives. We then ?train their trainers? and support them to scout, screen and select the start-ups and scale-ups to participate in the initiatives, emphasising the ones with the most promising potential for application areas (e.g. Galileo, Copernicus) or spinning-in/-out. Well-trained experts will assess their needs and co-define the services required for catalysing their growth in synergy with EU actions. Our service portfolio includes trainings, mentoring, networking and support to access financing and funding opportunities. A monitoring and evaluation framework will allow us to collect ample evidence on the performance of our solutions, improve them and follow up to train and engage additional intermediaries in SEE and CEE. We will support over 20 intermediaries to generate their own local initiatives, openly demonstrating and proving the replication potential of our solutions. We will then pack our solutions along with business models and lessons learnt into a re
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Can peak water be considered a tipping point for water security in mountain river basins?' (TIPPING-RIVERS) under Horizon Europe.

assistant: **Objectives**

Peak water describes the point in time beyond which glacier and snow melt irreversibly reduce. It is widely seen as a tipping point at which hydrological processes in glacierized catchments are forever altered and water security is put increasingly at risk. Through TIPPING-RIVERS, I will systematically quantify the impact of the point in time beyond which glacier and snow melt irreversibly reduce peak water on water security. Using a comprehensive risk assessment approach (risk = hazard x exposure x vulnerability), I will quantify the risk of a ‘tipping’ from a water secure to an insecure region in two case study catchments. Given my background in hydrology, I will put a strong focus on the hazard-component, identifying ecohydrological catchment characteristics which accelerate, delay or hinder negative impacts of melt water loss. To translate the natural hazard into risk for society, I will combine the hydrological analysis with the assessment of the exposure as well as the vulnerability of downstream communities. The assessment of local tipping points conducted in this project, will be based on the planetary boundaries framework. Its use for the identification of local boundaries has thus far been limited but highly demanded to better anticipate and prevent irreversible and adverse changes to the environment. TIPPING-RIVERS will advance the science in this field by developing a framework for local freshwater boundary assessments.


**Keywords:** Peak Water, tipping-points, water security, freshwater boundary framework
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Understanding the neural mechanisms of multisensory perception based on computational principles' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The brain’s multisensory faculty provides considerable benefits for perception, as the adaptive weighting of multiple inputs increases perceptual reliability and flexibility. However, failure of this process results in an impoverished percept, and links to perceptual deficits that occur along our life span and in disorders such as Autism. While the brain efficiently handles multiple sensory inputs, we still have a limited understanding of the underlying neural mechanisms. To advance our knowledge of how the brain processes its environment I propose a pioneering agenda that departs from previous descriptive work by linking the underlying brain mechanisms with specific multisensory computations and perception.Precisely, I propose a programme that combines computational models of multisensory interactions with high-density neuroimaging and perceptual tasks. This interdisciplinary research builds on my pioneering multisensory work but will provide a qualitatively new and principled understanding of the neural processes that implement the well-known perceptual benefits of multisensory information.The proposed programme advances our knowledge by addressing the following timely questions: What are the neural processes transforming multiple sensory inputs to a unified representation guiding behaviour? How does the brain control the dynamic weighting of multiple inputs and assigns these to either a single or multiple causes? Which perceptual and neural processes are affected in the multisensory deficits seen in autistic individuals or the elderly?This agenda, by its innovative methods and deliverables, will offer a principled and comprehensive understanding of how the brain handles and merges multiple sensory inputs, and provides a framework for addressing continuing and pressin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Optimized electric Drivetrain by INtegration' in the context of a Seventh Framework call.

assistant: **Objectives**

One of the primary goals in the development of electric vehicles is to reduce the cost while ensuring performance and meeting automotive quality standards to reach market acceptance. System design of the electric power-train is based on existing components currently in different phases of the development process. Integrating these components into an electric power-train using current designs can only result in a suboptimal solution since components are generally not designed for integration, but rather to optimally fulfill the supplier's requirement specification.It is postulated that the most cost effective and reliable design is a highly integrated solution that reduces interfaces, variations of components and uses synergy effects e. g. common housing/casing wherever possible. The large design effort for such integration requires sufficiently large number of produced systems and will thus become attractive when the market enters the strong growth phase. This is expected around 2020 or early as 2018.Optimally integrated solutions are not achieved by simply assembling existing components, but by ensuring that components are designed according to integration aspects of the system requirements and by implementing and testing the complete integration early in the process.This project aims to develop a compact, efficient, highly integrated electromechanical powertrain, production optimized to deliver key cost reduction goals. The partners will focus on optimizing the integrated unit for an entry power level of a typical urban vehicle. In parallel they will assess scalability potential to meet the performance criteria of other platforms. Innovative simulation and optimization software tools will be used early in the concept phase to assess optimal design variations, the outp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Precision measurments of quantum transitions in exotic atoms' (QUARTET) under Horizon 2020.

assistant: **Objectives**

Based on our understanding of the universe, we, who are made of matter, should not exist. This is due to the fact that the subatomic world is largely indifferent between matter and antimatter, predicting that they would be created in almost equal amounts in a big-bang scenario, and subsequently annihilate to form pure energy. This conundrum is called the baryon asymmetry problem. It is one of the major and most pressing unsolved questions in science today. One way of addressing this problem is to look for deviations between precision measurements and Standard Model predictions. However, a major limitation arises in the stage of comparison with theory due to nuclear-structure effects. Conducting measurements with exotic atoms overcomes this limitation, either by comparing measured properties between atoms and anti-atoms directly with no input from theory, or by measuring systems composed of particles with no internal structure. QUARTET - Quantum transitions in exotic atoms, will pursue both directions through two complementary experimental campaigns:1. Muonium spectroscopy using the most intense low-energy muon beam at PSI.2. Antihydrogen spectroscopy using the most intense low-energy proton beam at the ELENA beamline at CERN.QUARTET will focus on transitions in the microwave region of the electromagnetic spectrum, namely the classical Lamb-Shift, which for Antihydrogen has an added value: If no difference between matter and its counterpart is observed, this measurement will provide the first determination of the antiproton charge radius.


**Keywords:** Exotic Atoms, Microwave spectroscopy, Anti-matter research, Muonium, Low-Energy particles physics, QED test, Anti-hydrogen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Strategies and Predictive Maintenance models wrapped around physical systems for Zero-unexpected-Breakdowns and increased operating life of Factories' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Maintenance in general and predictive maintenance strategies in particular should now face very significant challenges to deal with the evolution of the equipment, instrumentation and manufacturing processes they should support. Preventive maintenance strategies designed for traditional highly repetitive and stable mass production processes based on predefined components and machine behaviour models are no longer valid and more predictive-prescriptive maintenance strategies are needed.The Z-Break solution comprises the introduction of eight (8) scalable strategies at component, machine and system level targeting (1) the prediction occurrence of failure (Z-PREDICT), (2) the early detection of current or emerging failure (Z-DIAGNOSE), (3) the prevention of failure occurrence, building up, or even propagation in the production system (Z-PREVENT), (4) the estimation of the remaining useful life of assets (Z-ESTIMATE), (5) the management of the aforementioned strategies through event modelling, KPI monitoring and real-time decision support (Z-MANAGE), (6) the replacement, reconfiguration, re-use, retirement, and recycling of components/assets (Z-REMEDIATE), (7) synchronizing remedy actions, production planning and logistics (Z-SYNCHRONISE), (8) preserving the safety, health, and comfort of the workers (Z-SAFETY).Z-Bre4k impact to the European manufacturing industry and the society can be summarised in the following: (i) increase of the in-service efficiency by 24%, (ii) reduced accidents, (iii) increased Verification according to objectives, (iv) 400 new jobs created and (v) over €42M ROI for the consortium.To do that we have brought together a total of seventeen (17) EU-based partners, representing both industry and academia, having ample experience in cutting-edge technolo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Euro-BioImaging - Research infrastructure for imaging technologies in biological and biomedical sciences' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Euro-BioImaging brings together imaging technologies stretching from basic biological imaging with advanced light microscopy, in vivo molecular imaging of single cells to animal models up to the clinical and epidemiological level of medical imaging of humans and populations. Euro-BioImaging, in close consultation with its stakeholders, will address the imaging requirements of both biological and medical imaging research communities by creating a coordinated and harmonized plan for infrastructure deployment in Europe. Euro-BioImaging infrastructures will be planned to provide access to state-of-the-art equipment as well as to provide training and continue the development of imaging technologies to be able to offer them as new services. The vision of Euro-BioImaging is to provide a clear path of access to imaging technologies for every biomedical scientist in Europe.The Euro-BioImaging infrastructure will be focused on imaging technologies grouped around different scales of biological organization, from the single molecule to the whole human organism. Euro-BioImaging will therefore develop a plan to construct and operate a set of complementary and strongly interlinked infrastructure facilities appropriately distributed across the European member states. To achieve this, Euro-BioImaging will define the legal and governance framework with its currently 22 member states and develop a finance plan in close cooperation with national funding bodies as well as with the European Commission. The key objective of the Euro-BioImaging preparatory phase project is to integrate these plans into an overarching business plan that provides a realistic basis for construction and operation of the Euro-BioImaging infrastructure. Through the combination of these technological and strategic ob
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Novel conducting copolymErs for Multicolor Electrochromic DEviceS (ECDs)' to be submitted under Seventh Framework.

assistant: **Abstract**

One large sector of electronics industry is that of electrochromic devices (ECDs). Electrochromism is the reversible optical change in a material induced by application of an external voltage. Many inorganic and organic species show electrochromism. Conducting polymers (CPs) are a class of electrochromic materials (ECs) which gain importance rapidly, due to the combination of processability, fast response times, and high optical contrasts and the ability to modify their structure to create multicolor ECDs. The most common applications of ECDs include a variety of displays, smart windows as well as spacecraft thermal control and computer data storage. Smart windows can be used in buildings and automotive applications in order to control the incident daylight and glare according to the occupants’ comfort. They are considered a proper technology for sustainable development and their market is expected to grow in the following decade since their use leads to minimization of the power consumption in buildings and cars.One of the main challenges is to develop novel CPs for multicolored ECDs, capable for large scale production. To date, the multicolor EC polymers reported have several important disadvantages, such as low stability and poor processability. The aim of the proposed project is to produce copolymers with proper absorption spectra through the entire visible region of the electromagnetic spectra, study their electrochromic behaviour and apply them in multicolored ECDs. The main objective is to manufacture ECDs with exceptional operating characteristics and enhanced stability by designing the monomers and the polymerization procedure in order to produce copolymers with defined structures. Since these materials are intended for commercialization, the entire production