RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Experimental investigations of the flow interactions between the first guide vanes and the impeller of the radial compressor' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

First guide vanes are an important part of a radial compressor stage. The flow interactions between the first guide vanes and the impeller of the radial compressor are not explained enough yet. In the project the experimental investigations for guide vanes of two different geometry will be carried on - one palisade with the S - shape profiles and one with the two-part profiles. The earlier investigations shown that the improving of the flow parameters between the first guide vanes and an impeller can be expected with the use of these palisades. The investigations should be carry on as a part of the common project of Turbo machinery Laboratory of University Hannover in Germany and Von Karman Institute for Fluid Dynamics in Rhode Saint Genese in Belgium Optimisation of the inlet guide vanes II". Investigation results will be used as a base for comparison with the numerical simulation results. Better recognition of the flow interactions and a simplified guide vanes calculation model as a results of the project are expected. The work at the Turbo machinery Laboratory of University Hannover should give the applicant possibility to carry on investigations that could not be carried on at the Chair of Thermal Engineering of the Poznan University of Technology, because of lack of the test facilities and equipment that make possible more serious investigations of the radial compressors, investigations that could be carried on with the use of equipment and the test facilities being in possession of Turbo machinery Laboratory of University Hannover. Also mastering of new measurement and data elaboration methods, as well as new methodologies of research will be a benefit. Very independent work is expected, including very close collaboration with the production facility. Learning fro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Relooking at Statutory Rape Laws in Malaysia: Psychosocial Characteristics of Sexual Relations among Underage and Adult-Child Partners, Sexual Motives and Perception of the Criminal Justice Personnel', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Statutory rape laws are designed to protect children from the manipulation of adults into having sexual intercourse. However, in Malaysia, statutory rape laws are applied even on male adolescents who are close in age with their female partners. This is problematic because applying these laws into male children will criminalize their normative sexual behaviors which has long-lasting damaging effects. In addition, the perception of the criminal justice personnel on sexual behaviors of children also cements the blanket applications of statutory rape laws onto every case involving female children. To reform the use of statutory rape laws in Malaysia, data on the sexual relations between close-in-age partners and adult-child partners are needed. This study has three research objectives. First, I aim to explore the perception of the criminal justice system personnel (i.e., prosecutors, police officers and probation officers) towards the implementation of statutory rape laws on adolescents in Malaysia. Second, I would like to investigate the psychosocial characteristics (sexual and antisocial dimensions) of sexual relations involving two close-in-age children in comparison with sexual relations involving adults and children. Lastly, I aim to explore the psychosocial-cultural motivations behind the pursuance of sexual relationships among Asian adolescents. The design of the proposed study will be a mixed design, employing both quantitative (to achieve research objective 2) and qualitative (to achieve research objective 1 and 3). For the quantitative part of the study, a hypothesis will be tested which is: Close-in-age sexual partners differ in terms of psychosocial characteristics compared to adult-child sexual partners. This will be tested using a binary logistic regression. T
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Autoimmune Reaction or Tolerance - Endosymbiont Mitochondria and the Immune System' (ARTEMIS).

assistant: **Innovation**

Mitochondria, the powerhouses of our cells, are remnants of a eubacterial endosymbiont. Because mitochondria retain many hallmarks of their bacterial origin, they have recently been implicated in the etiology of systemic inflammatory response syndrome, a frequent cause of death in intensive care units. Remarkably, mitochondria are immunologically inert under normal homeostatic conditions, raising the fundamental question: how does the immune system distinguish mitochondria from resemblant bacterial pathogens? We hypothesize that mitochondria harbor distinct molecular signatures identifying them to the immune system. To address our hypothesis, we will investigate immune handling of intact mitochondria and mitochondria-derived danger-associated molecular patterns. The research objectives are to examine: 1) if isolated, intact mitochondria in vitro elicit pro-inflammatory signals or are recognized specifically as non-pathogenic by immune cells, 2) immune handling of intact and disrupted mitochondria in vivo by two-photon intravital microscopy, and 3) the role of innate signaling pathways in determining pro- or anti-inflammatory responses to mitochondrial challenges in vivo. The applicant has an international profile and an outstanding track record. He will combine a strong background in immunology with an interdisciplinary approach transcending the boundaries to organelle and symbiosis research. The project entails training in two-photon intravital microscopy at the outgoing host, the Immune Disease Institute, Harvard Medical School. This cutting-edge technique has emerged recently as a powerful tool for studying immune function in real-time in the intact organism. Hence, theoretical developments and technical innovations have converged to pave the way for the implementati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'PREDICTIVE MAINTENANCE SYSTEM FOR INDUSTRIAL MACHINERY BASED ON INDUCTION MOTOR CURRENT ANALYSIS, WIRELESS AND SELF-POWER TECHNOLOGIES' under Sixth Framework.

assistant: **Concept**

With the growing adoption of electronics in today's industrial systems, increasing reliability is often hampered by the failings of mechanical components. Reliability is a major issue in today's highly competitive marketplace, the costs associated with unexpected machine failure having potentially drastic effects on a company. Predictive maintenance systems and services are very often unaffordable for SMEs. Therefore there is a need for a low cost means of non-subjective on-line, pre-vibration condition monitoring system for detecting malfunctions in gearboxes, rotating shafts, bearings and similar systems. Currently, only the largest, most critical motors are monitored. Leveraging new, inexpensive RF components and integration techniques, along with advances in microprocessor technology, it is possible to provide an economic solution for wirelessly monitoring motor operating parameters - such as temperature, vibration, current, etc. - for all classes of motors, thus creating enormous potential for energy and cost savings.The proposed LOPTIM technology will surpass the state of the art by utilising the novel combination of stator current analysis, along with the current flow from the inverter to the motor and machinery for continuous pre-vibration monitoring. LOPTIM will combine low powered innovative technology, artificial intelligence and a wireless communication network that will render the device both intelligent and autonomous, allowing continuous centralised monitoring of the plant at a fraction of the cost of current alternatives. The generic technology will find applications in areas where motors, pumps, gearboxes or drive chains need to be monitored on a continuous basis, such as fluids processes in chemical industries, motor generator systems, serial trunk con
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Net-enabled security through operational resilience'.

assistant: **Objectives**

The NESTOR project contributes to cutting-edge security solutions within the area of multi-sensing and data fusion.The general objective of the NESTOR project is to research all critical topics for the future development of a novel, next generation network centric security system. The key issue here is to sense, connect, interpret and analyse all relevant sources of information at any time, and to take the consequent right decisions and actions.The scientific challenges are embedded in three research topics:- Secure infrastructure;- Advanced use of information;- Decision support.The NESTOR-project offers excellent opportunities for six university graduates (M.Sc. degree) to receive early stage training in the field of network centric security technology. The proposed research topics offer the fellows the opportunity to prepare for a PhD degree.Hosted at the Innovation Department of the Business Unit Combat Systems of Thales Nederland B.V., the fellows will be surrounded by the best resources available to do research in this area. Tight co-operation with the University of Twente (via the T-Xchange cell, in particular with the Centre for Telematics and Information Technology (CTIT), enhances the effects of the research training.The fellows will be stimulated to learn and to train, but also to contribute to scientific developments. The leading research position of Thales facilitates the fellows to become experts themselves, in their own scientific/technological discipline, with a profound focus on personal development and security technology.From these perspectives, Thales-NL clearly contributes to promoting research careers within the European Research Area and encourages young researchers to progress into long-term research careers.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'A diagnostic test for cochlear synaptopathy in humans' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The CochSyn-test aims to diagnose the first signs of permanent hearing damage with a 10-15 min clinical hearing- screening test. The test quantifies cochlear synaptopathy, i.e. damage to the cochlear auditory-nerve fiber synapses due to ageing, noise-exposure or ototoxicity, with a non-invasive auditory test. Because synaptopathy is associated with reduced speech intelligibility and occurs before the audiogram shows signs of hearing damage, our test is more sensitive than the audiogram (present clinical standard) and can quantify a widespread form of sensorineural hearing loss. The CochSyn test makes early-diagnosis and early-intervention possible, which the WHO determined as cost- effective in reducing the financial burden associated with untreated hearing loss.In this PoC project, we plan to fine-tune the CochSyn-test and build a normative dataset of test outcomes for a diverse population of people at risk for synaptopathy. This dataset is necessary to (i) determine the application area of the test and enable a precise diagnostic interpretation, (ii) convince ENT doctors about adopting the test and companies to invest in it, and (iii), convince health agencies and policy makers that synaptopathy is an important health risk, given its impact on degrading speech intelligibility in noisy listening environments.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'EFFECT OF SOIL ARCHITECTURE ON TRANSPORT AND RETENTION OF SILVER NANO-LITTER' (SoilArchnAg) targeting Seventh Framework.

assistant: **Abstract**

A lack of understanding of the human and environmental health implications of nano-materials has deterred public and scientific support for nanotechnology evolution across industries. Nano-silver in particular has gained increasing popularity due to its biocidal properties in the garment industry to create odor-free clothing. An increase in “nano-litter” release to the environment is expected from erosion by product use and land application of nano-litter enriched wastewater sludge. This project will investigate the transport of nano-silver in soils through laboratory experiments using a novel 3-dimensional soil model technique that creates reproducible replicates of real soil pore networks, and simulations that combine non-equilibrium statistical physics of particle-solid interactions with information of Lattice-Boltzmann flow fields. The objectives are to: i) determine the effect that soil structure has on the transport of nanoparticles, ii) assess the capacity of soils under different land management practices (and therefore different soil architectures) to filter out suspended nano-litter from groundwater, and iii) develop a modeling tool to help industry forecast the propagation of nano-enabled products and their derivatives through soil environments from product use and disposal. The findings of this study are expected to directly impact environmental policy in the host country as well as worldwide.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Campus Iberus International Doctoral Programme of Interconnected Universities' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

IberusINTERDOC is an International Doctoral Programme of 4 Interconnected Universities of Campus Iberus aimed at recruiting 23 Doctoral Candidates  (DCs) of excellence to develop Interdisciplinary PhD projects for 48 months in Campus Iberus territories.  Campus Iberus is the Consortium of International Excellence of the Ebro Valley bringing together four public universities from neighbouring regions in northeast Spain: Universidad de Zaragoza, Universidad Pblica de Navarra, Universitat de Lleida and Universidad de La Rioja. Campus Iberus strategy is set on the principles of aggregation, internationalisation and specialisation on five strategic areas, in line with the priorities of the smart specialization strategies (RIS3) of the four regions involved  (Aragon, Navarre, La Rioja and Lleida in Catalonia): 1) Agri-Food & Nutrition; 2) Health Technologies; 3) Energy & Sustainability; 4) Social & Territorial Development; 5) Circular Bio-Economy. DCs will be recruited in 2 calls open for 2 months to apply for a variety of research topics across those 5 areas. Appointments will be no later than M12 (1st call) and M19 (2nd call) to offer 48 months contracts. The last 6 months of the contracts will be fully financed by own funds of Campus Iberus universities to cover 4 years even if exceeding the programme (M60+6). The programme will offer DCs excellent supervision and professional development, counting with preidentified potential supervisors proving experience and work in multidisciplinary projects and large networks of collaborators. A total of 116 academic (48%) and non-academic partners (52%) have associated to this programme to provide secondments, trainings and career enhancing opportunities, besides the networking events and special training programme organised by Campu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Advanced Research on Viroid Pathogenesis and Control for Agricultural Sustainability'.

assistant: **Concept**

Viroids, the smallest infectious pathogens, cause crop losses in the millions of euros every year and affect crop yields and quality worldwide. Climate change allows viroids to invade new geographical areas and hosts, posing a threat to global food security. ViroiDoc is an international, multidisciplinary and cross-sectoral PhD network that aims to thoroughly understand and tackle viroids in line with the European Green Deal and the Farm-to-Fork strategy for sustainable crop production and food security. To achieve this, ViroiDoc will: (i) fill knowledge gaps in molecular pathogenesis and host interactions of viroids, (ii) assess the impact of climate change on viroid infection, (iii) characterize emerging viroids and viroid-like RNAs in plants and fungi, iii) develop innovative CRISPR/Cas and sensor-based diagnostics for early detection of viroid infections, and iv) provide viroid interventions, including breeding targets, antiviroidal agents, and RNA-based biopesticides. ViroiDoc's mission is to prepare 10 doctoral students (DCs) for careers in molecular biology, bioinformatics, research, product and service development in European agriculture and innovation development. The ViroiDoc consortium, composed of researchers with complementary expertise in basic research (molecular biology, biotechnology, genetics, bioinformatics), applied sciences (nano- and sensor technologies) and innovation development (plant protection, plant diagnostics, plant breeding), will provide DCs with excellent scientific, methodological and soft skills. Exposure to an international environment and different industries will allow them to build a valuable network of contacts, providing a solid foundation for future research collaborations and direct employment opportunities. Finally, ViroiDoc w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Identifying novel regulatory mechanisms of miRNA functions' (MIREG) targeting Seventh Framework.

assistant: **Abstract**

microRNAs (miRNAs) are master regulators of gene expression capable of defining and altering cell identity. Because of their potency, small size, simple mode of action (target recognition through a Watson-Crick type of base pairing) and the possibility to inhibit them in vivo, miRNAs are valuable therapeutic targets. Recently, we have used novel functional-genetic screening approaches and identified the miR-372, 373 and 520, as well as the miR-221&222 family as cancerous miRNAs. These miRNAs are oncogenes, as they are deregulated in specific types of cancers, target tumor suppressors and their inhibition reverts cancerous phenotypes. However, at present almost nothing is known about the mechanisms governing the expression and function of these, as well as many other, oncogenic miRNAs. Here, I propose experiments to identify and characterize factors affecting the activity of oncogenic miRNAs using an array of molecular and genetic tools. Our preliminary results indicate the existence of novel regulators and mechanisms of miRNA activity. We therefore believe that the information collected here not only will lead to a better understanding of miRNA functions, but will also identify novel modes of manipulating miRNA activity in human disease.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'European building waste guide - avoiding and separating waste on building sites by organisational and technical measures adopted cooperatively by sme's'.

assistant: **Objectives**

Until now, the decentralized disposal of waste materials generated by individual same building firms has represented a considerable additional cost in terms of time and money. Due to the small amounts of waste produced by individual building firms and the lack of knowledge of environmentally waste management strategies, waste which could be recycled is thrown away and valuable disposal area un-necessarily used up. The research project includes the goal of organizing building procedures in several EU states in such a way that building is carried out with a minimum of waste production and with an emphasis on recycling. A system of standardized waste indexes is to be determined and international standards for sustainable as the management are developed. The dissemination of the results is to take place by way of a European building waste guide, which will make the production of waste transparent from the planning stage to the actual realisation of building projects.