RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Sources and sinks of greenhouse gases from managed european grasslands and mitigation scenarios'.

assistant: **Innovation**

In support of the European post-Kyoto policy, the GREENGRASS project will measure the net global warming potential resulting from the exchange of CO2, N2O and Twitch managed European grasslands and assess the European wide mitigation potential of key field and farm management scenarios. Long-term micrometeorological measurements at sites in a European wide network will be complemented by experimental assessment of the effects of management options bonnet fluxes. The results will be used to refine emission factors used in national inventories and to evaluate farm-level mitigation scenarios with respect to tenet global warming potential associated to grassland management. These evaluations will be conducted at the field and farm level, and by upscalingsimulation results to the Europe scale.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Involvement of the endocannabinoid system in posttraumatic stress disorder' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Posttraumatic stress disorder (PTSD) belongs to the most frequent anxiety disorders. It develops in the aftermath of a traumatic life event and represents a clear public health problem. In spite of its increasing incidence, there are no established effective treatments for this disorder. In addition, even though a broad body of evidence concerning neurobiological correlates of this illness, the pathomechanisms of PTSD is still poorly understood. Therefore, there is a need to identify new therapeutic targets/strategies for PTSD. Interestingly, only 10-15 percent of the people confronted with a trauma develop PTSD in its aftermath. This points to the existence of highly efficient “salutogenic” (i.e. health promoting) factors. With the help of animal models we have accumulated preliminary evidence that the endocannabinoid system of the brain plays an important role in the modulation of processes occurring in PSTD and is pointed out as a potential therapeutic target for this neuropsychiatric disorder. The involvement of ECS in the development of PTSD symptoms seems to critically depend on the neuronal population affected. For instance, CB1 on glutamatergic neurons constrain the expression of fear responses, once the averseness of the test situation has surpassed a certain threshold. Therefore, the general objective of this research proposal is to unravel the time point, sites and consequences of attenuated CB1 buffered glutamate signalling in a mouse model of PTSD. To address this issue, we will combine genetic, in vivo imaging, electrophysiology, behavioural and biochemical studies in mice. The achievement of these objectives will provide new insights into the mechanisms underling the involvement of endocannabinoid system into the adverse consequences of a traumatic experi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Synthetic toolkit for fragment oriented synthesis' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Fragment-based ligand discovery (FBLD) has become a mainstream strategy to discover new drugs to enable the treatment of conditions with unmet medical needs. Despite the remarkable rise of FBLD, significant chemical challenges remain in the field; firstly, elaborated fragments tend to be synthesised de novo when direct growth would be much more advantageous. Secondly, the currently available toolkit for fragment elaboration tends to exacerbate an uneven exploration of chemical space, yielding flatter and more lipophilic compounds.SYNFOS will allow Alexandre Trindade (the fellow) to join the laboratory of Professors Adam Nelson (host supervisor) and Steve Marsden (host co-supervisor) at the University of Leeds (Host) and develop research expertise in fragment-based ligand discovery; catalysis to enable molecular discovery; protein-protein interaction (PPIs) inhibition; and high-throughput X-ray crystallography (via secondments to Diamond (Partner)). In doing so, the fellow will (a) enhance his prospects of becoming an independent academic group leader in Europe and (b) address the need to train researchers in key multidisciplinary areas such as medicinal chemistry and chemical biology and (c) develop cutting edge synthetic methods that facilitates the fragment-based discovery of new inhibitors for protein-protein interactions. By building in fragment hits from the Host laboratory, the fellow will establish a synthetic toolkit enabling the functionalization of C-H bonds within N-heterocycles with a wide range of medicinally-relevant groups. The fellowship will explore three main modes of reactivity to establish the functionalization of sp3-hydridised carbons with heterocyclic fragments and showcase the value of the synthetic toolbox through the discovery of fragments hits
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Development of a ceramic hybrid receiver for biogas fired dish-stirling-systems for electric power supply ('BIODISH')' (BIODISH) targeting Fifth Framework.

assistant: **Abstract**

Dish/Stirling-systems have demonstrated that they are the most efficient solar electric systems. But high system costs prevent the introduction to the market. Since the Stirling engine is independent of the heat source, the use of an additional, renewable energy source like biogas could enhance the yearly running time and therefore the profitability. To fulfil all demands of such a hybrid receiver, the use of SiC-ceramic seems to be the most promising way. The main objective of this project is the development of a compact ceramic hybrid receiver, absorbing the solar radiation on the one side and being heated by a burner wont he other side. After the production of a prototype and first tests in gas mode, the hybrid receiver will be installed and tested on a Dish/Stirling-system. An assessment on the environmental benefits and an economic analysis will complete the project, providing the necessary information for future marketing activities.1.) non-LTE populations profiles have been generated and distributed to the consortium2.) new complementary spectroscopic data have been generated and distributed to the consortium3.) forward model spectral calculations have been intercompared; differences have been understood and forward model deficiencies have been removed4.) retrieval processors have been validated by blind test retrievals on the basis of synthetic data5.) robustness of retrieval processors has been proven by application to real MIPAS measurement data6.) characteristics of the MIPAS instrument were assessed and described.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Development and Epilepsy - Strategies for Innovative Research to improve diagnosis, prevention and treatment  in children with difficult to treat Epilepsy' to be submitted under Seventh Framework.

assistant: **Abstract**

DESIRE will focus on epileptogenic developmental disorders EDD, i.e. early onset epilepsies whose origin is closely related to developmental brain processes. A major cause of EDD are malformations of cortical development (MCD), either macroscopic or subtle. EDD are often manifested as epileptic encephalopathies (EE), i.e. conditions in which epileptic activity itself may contribute to severe cognitive and behavioral impairments. EDD are the most frequent drug-resistant pediatric epilepsies carrying a lifelong perspective of disability and reduced quality of life. Although EDD collectively represent a major medical and socio-economic burden, their molecular diagnosis, pathogenic mechanisms (PM) and rationale treatment are poorly understood. Specific objectives of DESIRE are to advance the state of the art with respect to: (1) the genetic and epigenetic causes and PM of EDD, particularly epileptogenic MCD, to elucidate molecular networks and disrupted protein complexes and search for common bases for these apparently heterogeneous disorders. (2) the diagnostic tools (biomarkers) and protocols through the study of a unique and well-characterized cohort of children to provide standardized diagnosis for patient stratification and research across Europe. (3) treatment of EDD using randomized, multidisciplinary clinical protocols and testing preclinical strategies in experimental models to also address novel preventative strategies. The workplan spans from clinical observation, to whole exome studies, cellular and animal models and basic research, identification of biomarkers and improvement of diagnostic methods, and back to the clinical trials and assessment of innovative, targeted treatment strategies. The consortium partners have an outstanding track record in genetics, ba
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Emotive Virtual cultural Experiences through personalized storytelling' in the context of a Horizon 2020 call.

assistant: **Objectives**

Storytelling applies to nearly everything we do. Everybody uses stories, from educators to marketers and from politicians to journalists to inform, persuade, entertain, motivate or inspire. In the cultural heritage sector, however, narrative tends to be used narrowly, as a method to communicate to the public the findings and research conducted by the domain experts of a cultural site or collection.The principal objective of the EMOTIVE project is to research, design, develop and evaluate methods and tools that can support the cultural and creative industries in creating Virtual Museums which draw on the power of 'emotive storytelling'. This means storytelling that can engage visitors, trigger their emotions, connect them to other people around the world, and enhance their understanding, imagination and, ultimately, their experience of cultural sites and content. EMOTIVE will do this by providing the means to authors of cultural products to create high-quality, interactive, personalized digital stories. The EMOTIVE project targets two main groups of users:1. Authors: members of the cultural and creative industries in charge of creating interactive cultural experiences (i.e., interactive stories) and making them available to the visitors.  2. Visitors: people experiencing the cultural site through a “World” created with the EMOTIVE Authoring System. They join in the available experiences when entering the site or when remotely connecting to the site’s Virtual Museum. The project results will be evaluated and validated in major cultural sites in Europe through an extensive network of cultural organizations and creative industries that have expressed their interest to the project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Babbler feasibility study in adjacent market segments.' (Babbler) under Horizon 2020.

assistant: **Objectives**

Babbler is a next-generation seal for supply-chains. Supply-chain security is flawed and unchanged in 30 years. If you transport or store goods, it is difficult to know that your goods were treated correctly. For decades the supply chain industry has depended on bolt/cable seals, documentation and locks, knowing that these provide extremely limited safeguards and evidence trails. As a result theft, people trafficking and narcotics smuggling are rampant. An estimated 8% of medicine sold worldwide is counterfeit (Source: WHO 2015). Improper storage is detected too late to prevent waste. In addition, inspection delays are a major cost in the total supply chain.Babbler uses IoT and an inverted evidence principle to provide much better assurance of cargo security problems. In 2015 we were selected for an accelerator in the EU FIWARE program and in that accelerator won a cash prize for best startup in 2016. The accelerator provided funding so we could create and test a solution for shipping containers with business partners (Royal FloraHolland, Dutch Customs Organisation, Seatrade and others). Although Babbler proved its value in those trials and is attracting international interest, the shipping industry is conservative and slow-moving. To use Babbler a number of links in the supply chain have to decide to work together, which makes the buying process slow. We concluded that we can grow faster by focussing on niches in the supply chain, rather than an entire chain itself. We have identified several candidate market segments but need funds to test our assumptions and determine if Babbler needs to be tweaked accordingly. We are considering: 1. Transport and storage of medical supplies, 2. TAPA level 2 certified road carriers, 3. Road carriers that EU cross borders with people
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Dual-Layer Coatings for Iron and Steel Corrosion Protection' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Corrosion undermines metal integrity, resulting in significant environmental and economic damage (exceeding $ 2.5 trillion). The anti-corrosion coating market was $ 34.8B in 2022, however, anti-corrosive coatings have three limitations: (1) High costs (2) Toxicity (3) Limited effectiveness. During my ERC project we developed and patented a technology that uses a dual-layer coating, engineered at the molecular level to provide a highly stable coating on iron to mitigate corrosion formation. The system consists of a primer monolayer of N-heterocyclic carbenes (NHC) molecules, that is strongly anchored to the metal and a top layer of a tailored polymer network, chemically linked to the NHC monolayer. The dual-layer coating yields superior corrosion resistance (up to 99.5% effectiveness) with no toxicity effect and can be produced and delivered at low costs. This project aim is to assist us in creating a spin-off company serving several market sectors (e.g. Oil and Gas, Marine, Construction, Aerospace, etc.). However, these sectors represent conservative industries which require rigorous proof and client education of the added value provided by our dual-layer NHC-polymer coating. Hence, the project will include requirements capture from potential partners and end-users for the design of thorough performance testing versus available solutions. Beyond testing, the technological process of the project will include development of (i) optimized dual layer coating formulation on iron and steel and (ii) spray-based procedures for on-site coating. The anticipated outcome is a scalable, commercially viable technology with a minimum protection efficiency of over 95% after 1000 hours of aging in corrosive media. This innovation holds significant potential for reducing maintenance cost
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Establishing museomics as a tool to inform the conservation of endangered species' to be submitted under Horizon Europe.

assistant: **Abstract**

Global biodiversity is being decimated by human activities, including agriculture, deforestation and land use change. This is causing unprecedented population declines and pushing species to extinction, especially in tropical ecosystems. Genetic health is an important measure of population viability, and to help identify populations at risk, this is now being included in conservation programs however, incorporating this level of information on genetic diversity can be challenging. Additionally, because standing levels of variation differ between species this makes assessing whether a population has low or high genetic diversity can be very difficult. In response, MUSEOMIC, will harness new ancient genetic and museomics techniques (sequencing of museum specimens), to measure changes in genetic diversity in three extremely vulnerable mammals (anoa, babirusa and Sulawesi warty pig) in the biodiversity hotspot of Wallacea. As an isolated tropical archipelago in Indonesia, Wallacea is the perfect natural laboratory for understanding how ancient and anthropogenic disturbances have impacted the genetic erosion of the three flagship mammals and is contributing to their decline. By tracking changes in genetic health through time and space, MUSEOMIC will gain insights into the extinction risk these unique taxa face and will directly benefit population management and long-term survival by identifying unique genetic diversity, designating conservation units, and making captive breeding recommendations. Hosted by Prof. L. Frantz at Ludwig Maximilian University Munich (LMU), through MUSEOMIC, Dr Rosie Drinkwater will gain new skills in bioinformatics and population genetics, grow her research network, and succeed as a future leader in conservation biology.


**Keywords:** Mammals, Wa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Seismic responses of deep-marine reservoirs (DEMARES)' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

This project will enable the fellows to perform quality research in resolving the problems of seismic and geological characterisation of deep-marine reservoirs. They will benefit from a team environment where scientists of different nationalities and domains work together. They will also be encouraged to interact with experts in sister Schlumberger Research and Development centres in Europe and the U.S.A. The project will be carried out in an industrial environment characterised by a reputation for scientific excellence, hence the fellow will benefit from exposure to issues involved in the applying fundamental research ideas towards the development of innovative, commercial concepts and products. The fellows will also benefit from the technical challenges posed by the deep-water environment on the oil and gas exploration and production business, and broaden their scientific expertise in an area that is economically promising. The company will benefit from research expertise and the input of fresh ideas from the fellows. The output of this project will be invaluable for the understanding and future development of deep-water reservoirs.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'A highly innovative size recommendation engine, disrupting the existing online apparel market by using big data and machine-learning algorithms.' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Fit Analytics GmbH is a Berlin-based ICT-SME, operating in the online fashion market. We are aiming to solve the two majorproblems of online fashion retail:1. High return rates (~40-50%) because many end users don’t know their size. ~65% of all returns are made due to non-fit.High return rates have certain side effects, e.g. enormous CO2 emissions.2. Low conversion rates to buy (less than 2% of all visitors convert into buyers; this is significantly lower compared to booksor electronics sold online) because end users are uncertain which size to buy. Today, only 9% of all garments are sold onlineand 91% are still sold in brick-and-mortar stores, whereas more than 50% of all books and electronics are sold over the internet.We have already deployed the world’s most widely-used Size Advisor (“FITA1.0”) in the market, an innovative ICT product tohelp end-users find the right size online by providing simple size recommendations. Within the framework of the SMEInstrument, Phase II, we are aiming to implement a new, ground-breaking size and product recommendation solution (“FITA2.0”) which will further disrupt the fashion retail market by using exclusive cross-shop purchase and return data for highly accurate size and personalized product recommendations.We have already developed a minimal viable product (MVP) of FITA2.0 that was successfully tested in an operationalenvironment (TRL6) on Gaastra, a leading Dutch-German brand.We have undertaken a commercial and technical feasibility study, with positive results, and this will form the basis for a business implementation plan to be created during the project. In order to accelerate the market acceptance of the solution after implementation, we have already signed contracts with several clients that have agreed to implement FITA2.