RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Living cell lasers: intracellular lasing induced by natural and polymeric microscopic resonators' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Can a living cell be turned into a laser? By aiming to coalesce biological cells with laser light, the most versatile tool that modern photonics has developed, LIVING LASERS explores entirely new ways to develop fully biocompatible lasers. The ability of vitamins, bacteria and even living cells to generate laser light has been recently demonstrated by the supervisor of the project, Prof Malte Gather. However, these and other experiments with active biological gain media are so far limited by the rigid and synthetic nature of the optical resonators, an essential part of any laser device. Introducing lasing in living cells independent of external resonators necessitates a conceptual change of the laser design. This is realized by internalization of microscopic resonators that will transfer the optical feedback directly into the cell. It is the main goal of this interdisciplinary project, located at the interface between material sciences, laser physics, photonics and biology, to demonstrate autonomous single cell lasing. Consequently, LIVING LASERS can be expected to start a whole new field in biophotonics and will help to overcome the boundaries between living nature and nowadays highly artificial and harmful laser technologies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Social Semantic Emotion Analysis for Innovative Multilingual Big Data Analytics Markets' (MixedEmotions), addressing dissemination and exploitation.

assistant: **Impact**

MixedEmotions will develop innovative multilingual multi-modal Big Data analytics applications that will analyze a more complete emotional profile of user behavior using data from mixed input channels: multilingual text data sources, A/V signal input (multilingual speech, audio, video), social media (social network, comments), and structured data. Commercial applications (implemented as pilot projects) will be in Social TV, Brand Reputation Management and Call Centre Operations. Making sense of accumulated user interaction from different data sources, modalities and languages is challenging and has not yet been explored in fullness in an industrial context. Commercial solutions exist but do not address the multilingual aspect in a robust and large-scale setting and do not scale up to huge data volumes that need to be processed, or the integration of emotion analysis observations across data sources and/or modalities on a meaningful level. MixedEmotions will implement an integrated Big Linked Data platform for emotion analysis across heterogeneous data sources, different languages and modalities, building on existing state of the art tools, services and approaches that will enable the tracking of emotional aspects of user interaction and feedback on an entity level. The MixedEmotions platform will provide an integrated solution for: large-scale emotion analysis and fusion on heterogeneous, multilingual, text, speech, video and social media data streams, leveraging open access and proprietary data sources, and exploiting social context by leveraging social network graphs; semantic-level emotion information aggregation and integration through robust extraction of social semantic knowledge graphs for emotion analysis along multidimensional clusters.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Constructing multi-locus models of demography for two drosophila sibling-species.', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

Demographic models will be constructed for two closely-related species of Drosophila based on multi-locus DNA sequence variability patterns, providing a point of departure from which to quantitatively assess the impact of natural selection at genes of interest.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Implementation of a pharmacogenomic approach to predict ABC transporter substrates and compounds selectively targeting multidrug resistant cancer', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

Although considerable progress has been made in treating cancer over the past decade, there are still over 8 million deaths annually from cancer worldwide. Despite considerable advances in drug discovery, resistance to chemotherapy confounds the effective treatment of cancer patients.Cancer cells can become resistant to a single drug or they may acquire broad cross-resistance to mechanistically and structurally unrelated drugs. ATP-binding cassette (ABC) proteins comprise the largest protein family, many m embers of which are of immediate medical importance. In particular, ABCB1 (MDR1-Pgp) actively extrudes many types of drugs from cancer cells, thereby conferring resistance to those agents.Thus, innate or acquired expression of P-gp is a major problem in cancer chemotherapy. ABCC2/MRP2 plays a pivotal role in the export of organic anions, bile acids and xenobiotics into the bile and also contributes to protection against orally ingested drugs. The substrate specificity of MRP2 has been widely investigated in the research community. The major challenge of the postgenomic era is to analyze vast amounts of data.In this context, the application of pharmacogenetics has the potential to improve the management of patients, particularly by providing the molecular basis for choosing among the increasing number of chemotherapeutic agents available for the treatment. The basic hypothesis of this proposal is that a pharmacogenomic approach can be exploited to characterize ABCC2/MRP2 substrates and to discover MDR1-inver se compounds that selectively kill multidrug resistant cancer cells.The proposed research utilizes a complex array of methodological tools involving chemoinformatics, a custom-made microarray, and biochemical assays for measuring and characterizing transport. These
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Nanophotonic Nanomechanical Mass Spectrometry for Biology and Health' (ENLIGHTENED), addressing dissemination and exploitation.

assistant: **Impact**

« Mass Spectrometry has become a routine analytical tool in modern biological research, and has gained in recent years a foothold in the realm of clinical diagnostic and screening. However, it is still costly, complex and because its principle relies on ionization, it is incapable of analyzing biomolecules with masses greater than a few MDa. Averaging more than 100 million particles per measurement, it is also incapable of characterizing the diversity of such heavy entities. ENLIGHTENED aims at demonstrating a breakthrough concept based on Photonic Nano-Mechanical Mass Spectrometry, able to perform analysis of bioparticles of high biomedical significance, of ultra-high mass, never so far characterized, with single-molecule sensitivity and unprecedented resolution. The long-term vision beyond the current proposal is to provide the biologists with a tool which will be transformative for fundamental knowledge, and to make possible cheap, handheld devices for personalized medicine.ENLIGHTENED proposes to use photons to shed light on unexplored species at the individual level, which is of high biomedical significance and will expand our understanding of simple life forms.”
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The Interaction Engine: Interactive foundations for communication' (INTERACT), addressing dissemination and exploitation.

assistant: **Impact**

This project addresses a serious gap at the heart of the social and cognitive sciences. The proposal is to fast-start an interdisciplinary science of human communicative interaction focused on sequences of contingent actions. The research will be guided by a novel hypothesis, the ‘interaction engine’, which holds that human interactive abilities are distinct from and phylogenetically older than our language capacity. Inverting the usual assumptions, the hypothesis suggests that the human interaction system is fundamentally universal, while the language system lacks substantial universals and is diversified by cultural evolution. The interaction system and language system therefore do not mesh neatly, and this can be detected in the domain of contingent action sequences – the crucial characteristic of human interaction. Two specific areas, (a) the timing of turn-taking and (b) the ascription of speech acts or intentions, will be examined from three distinct disciplinary perspectives:(i) cross-cultural corpus and experimental studies in a dozen languages,(ii) developmental studies (corpus and experiment based) from early infancy up to middle childhood,(iii) cognitive studies employing both behavioural measures (reaction time, eye tracking), and neurocognitive methods (EEG, fMRI).The ‘interaction engine’ hypothesis makes detailed predictions about cross-cultural universals, developmental trajectories, and processing complexities in both turn-taking and action ascription.The project aims to build an integrated, interdisciplinary science of communicative interaction. New developments (multi-media corpora, dual eye-tracking, EEG, fMRI, baby-lab techniques) now make this feasible. The PI and host institution are uniquely equipped to undertake this project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Enzymes as catalysts for hydrogen fuel cells. Assembly of a multicomponent enzymatic film at an electrode surface by a step-by-step method'.

assistant: **Innovation**

Molecular recognition performed by specialised biological molecules like antibodies or avidin is an useful tool for the construction of enzymes onto electrode surfaces. The objective of this project is to accomplish a experimental and theoretical study of enzymatic electrocatalysis in a multilayer structure where both the enzyme (a hydrogenase) and the redox mediator (a viologen derivative) are immobilized in a sequential manner. Briefly, this would imply the direct modification of the electrode surface hy a step-by-step construction, using the strong biotin-avidin affinity, of conveniently derivatized enzymes and redox mediators. The main goal of the proposed method is to obtain high catalytic currents without mediator in the bulk solution and to study the reversibility of such system in a large range of pH. This modified electrode could be the active part of a fuel cell using hydrogenase as catalyst instead of platinoids.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Membrane-assisted Ethylene Synthesis over Nanostructured Tandem Catalysts' (MemCat).

assistant: **Concept**

MemCat targets to deliver a proof-of-concept for the direct conversion of CO2 to ethylene by realizing tandem catalysts, which through nanostructuring will allow for consecutive CO2-to-methanol and methanol-to-ethylene conversions to occur in the same operational window. A fundamental understanding of the parameters governing the reactions will be gained through detailed operando studies of the tandem catalysts, which, in combination with theoretical calculations, will lead to the underpinning of the reaction mechanism and allow the rational improvement of the nanostructured catalysts to achieve an industry-relevant level of performance. Building on the consortium’s know-how, the catalysts will be deployed in a membrane reactor featuring a combination of tailored nanocomposite membranes, giving access to ethylene in a selective manner and high yield for the first time. The MemCat science-to-technology breakthrough will be achieved through a synergy of synthesis, catalysis, and theory to obtain novel nanostructured tandem catalysts, and the development of nanocomposite membranes for a prototype catalytic membrane reactor, replacing current multi-step conversion pathways with existing catalysts. The long-term vision of MemCat is to give access to green e-Polymers by providing carbon-negative plastic precursors using anthropogenic CO2 and green H2. The project will contribute to establishing the EU as the world leader in the use of CO2 as feedstock for chemical production.


**Keywords:** Reduction of carbon footprint, selective hydrogenation, monomers, ethylene, nanomaterials, membranes, selective gas separation, catalytic membrane reactor, operando methods
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Building knowledge and  tools to advance on promoting of freshwater urban ecosystems as nature based-solution for health and wellbeing in a changing word' (StreamScape) targeting Horizon Europe.

assistant: **Abstract**

Cities around the world are undergoing significant transformations and are facing substantial challenges in the form of urban of climate change and ongoing urbanisation. The idea that we can work with nature to improve our cities is now seen as vital. The concept of Nature-Based Solutions has emerged to foster sustainable development by transversally addressing social, economic, and environmental urban challenges. Although the attention to nature-based solutions inclusion is an important pillar of urban sustainability, a clear understanding how they can be implemented in the freshwater landscape, is still missing, even in face of the relevance of the urban freshwaters to wellbeing of the population. This investigation aims to fill this gap, by analysing the social and environmental impacts of urban streams as important nature-based solutions from protecting water quality to reducing natural hazards while preserving biodiversity and providing health and wellbeing benefits to population. By selecting as case studies Aveiro and Coimbra, the research project aims to promote the urban streams and their multiple ecosystem services as important nature-based solutions to mitigate the effects of urbanization and climate change on aquatic ecosystems,  in the human health and in the wellbeing of the population. The project will adopt the research strategies: to assess how urban development affect a capacity of urban streams to provide ecosystem services using well-established scientific methods and  investigate how the degradation of urban streams reflects on the local residents’ perception of the ecosystem services in terms of benefits, health and wellbeing. In addition, thematic maps of ecosystem services identified in the urban streams will be produced to demonstrate the releva
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Smart Shoot Remover' to be submitted under Horizon 2020.

assistant: **Abstract**

Removal of green shoots is a key step in vineyards and fruit trees, to control growth and improve production and quality of fruits. Shoots that grow on sides of the stems cause the plant to produce smaller fruits that may not ripen properly. By removing green shoots, plant produces better quality fruits (colour, size, ripening and weight) as sap concentrates flow in the growing areas. Current options to remove shoots are: (a) by hand: which force the worker to operate in a position that leads to injuries; (b) use of scissors: posing a high risk of spreading diseases/pests through sap with important drawbacks; (c) with a battery/fuel powered mechanical equipment: that implies high costs in terms of fuel consumption and equipment and can damage young stems; and (d) by chemicals application: that releases toxic products through herbicides. SSR (Smart Shoot Remover) is an innovative tool to quickly and completely remove green shoots from stems/trunks. It consists of two opposed interchangeable brushes, clamped around the stem/trunk and held via a guide system, which opens out the brushes in an adjustable angle, and a non-sharp blade, attached to one of the brushes guides, to remove the shoots by stripping, without damaging the plant. SSR allows to work 40% faster than manual techniques, saving 2.2 hours of workday vs. manual technique. It cost 98% less than mechanical equipment, requires only 1 operator against 2 of the mechanical/chemical removal and does not use fuel nor motorised equipment, reducing operational costs in >60€/h, and emissions. It reduces risk of spread of trunk diseases (ie. Esca complex), and improves of worker’s safety and ergonomics by preventing back injuries, falls/trips and cuts. We distributed 4.000 prototypes in 106 countries of the first version
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'A bioartificial pancreas to treat type 1 diabetes: optimization of cell survival and function in preclinical and clinical phases' (BIOSID) targeting Seventh Framework.

assistant: **Abstract**

MAILPAN (MAcroencapsulation of PANcreatic Islets) is a prototype of bioartificial pancreas usable in the human designed to treat type 1 diabetic patients. The prototype was developed along different stages since 1996 and led to the creation of the SME called Defymed in 2011. Next step is now to bring the prototype to the pre-clinical and clinical phases necessary to the ensuing commercialization of MAILPAN whose ultimate goal is to improve the life of at least 20 million persons in the world while providing positive effects on healthcare management and expenses, the environment and the competitiveness of the biomaterials industry.In order to reach this goal, CeeD and Defymed gathered a consortium made of seven partners from academia, clinical/public health research sector and industry/SMEs from three different European countries –Belgium, France and UK. The expertise gathered include encapsulation techniques, islet isolation, cell engineering, islet transplantation, islet preconditioning, surgical implantation, and medium formulation; items that are complementary and necessary to the implementation of the present project proposal.The project proposal of a 48-month duration intends to bring the most modern and up to date improvements that the bioartificial pancreas still needs and can receive such as to enhance cells survival inside the device by formulating a new adapted cell culture medium, to further lower the rejection risk by studying the biocompatibility and anti-inflammatory mechanisms, to test the prototype in small and large animal models, and to secure its further use in humans. Safety and bio-compatibility of MAILPAN device combined to the islets/pseudo-islets, will be assessed, in respect to the applied regulatory directives.