RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Polymer brush sensing arrays for the identification of pathogens'.

assistant: **Concept**

Surfaces with the capacity for selective recognition of particular pathogens would offer great potential in a number of biomedical applications, including diagnostic devices. Mammalian cells are decorated with a carbohydrate-rich layer, the glycocalyx, which facilitates cellular recognition. Carbohydrate-binding proteins can interact with these sugar motifs to facilitate highly selective recognition, a strategy which is exploited by many viral and bacterial pathogens. Such species have evolved to display recognition units on their surfaces which may interact with considerable affinity with glycan structures displayed on cellular surfaces. This molecular recognition constitutes a key step in the processes of infection or toxicity, and is therefore an attractive target for the development of diagnostic devices. In this project, Dr Clare Mahon proposes to develop surface-tethered polymer brushes which will mimic the glycocalyx in terms of facilitating adhesion of pathogens. Through the incorporation of different fluorophores, the surfaces will be used to construct sensing arrays which will enable the rapid and cost-effective identification of water-borne pathogens and common respiratory pathogens.


**Keywords:** polymer brushes, sensing arrays, biosensors, waterborne pathogens, respiratory pathogens
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Reprogramming cell identity to develop new therapies against Inherited Metabolic Disorders of the liver' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

Liver diseases are becoming one of the most common causes of mortality in developing countries, and orthotopic liver transplantation is the only available treatment. However, this procedure carries implies indefinite immunosupression treatment associated with heavy side effects and eventual rejection. Furthermore, an increasing number of patients die while on the liver transplant waiting list due to the shortage of donor livers. Hepatocyte transplantation recently became an alternative to transplantation for the treatment of life-threatening Ineherithed Metabolic Diseases (IMDs) of the liver. However, this approach is also hampered by the lack of donors and by the difficulty in expending hepatocytes in vitro. Therefore, developing alternative source of hepatocytes represents a major challenge for the regenerative medicine field. Pluripotent stem cells generated from reprogrammed somatic cells (human Induced Pluripotent Stem Cells or hIPSCs) represent an advantageous solution since they can proliferate indefinitely in vitro while maintaining their capacity to differentiate into a broad number of cell types including hepatocytes. In addition, hIPSCs could enable the production of patient specific cells fully immuno-compatible with the original donor thereby avoiding the need for immune suppressive treatment. Here, we propose to systematically address the limitations preventing the use of hIPSCs for cells based therapy of IMDs. We will first develop novel methods to generate “better” hIPSCs fully compatible with clinical applications and to differentiate them into adult hepatocyes. In parallel, we will establish a novel approach for editing the mammalian genome and to correct the genetic defects associated with IMDs. Finally, we will validate the safety and the functionali
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Prevention and Screening Innovation Project Towards Elimination of Cervical Cancer' in the context of a Horizon 2020 call.

assistant: **Objectives**

The proposed Prevention and Screening Innovation Project towards Elimination of Cervical Cancer (PRESCRIP-TEC) will lead to effective and innovative cervical cancer screening, including direct treatment and follow-up for women in resource-poor or hard-to-reach settings in the world, by improving availability, accessibility, acceptability and quality of services. PRESCRIP-TEC will conduct implementation research into cervical cancer screening and secondary prevention in different settings in four countries over three continents: Bangladesh and India in Asia, Uganda in Africa, and Slovakia in Eastern Europe. We will analyse patient- and health services-related facilitators and barriers for uptake of cervical cancer screening in low- and middle-income countries and in vulnerable groups in Eastern Europe. By taking existing screening protocols in the four countries, we will introduce 1) interactive information with communities via mobile devices and social media; 2) client-friendly, community-based strategies, with self-test for high risk HPV infection; and 3) artificial intelligence in gynaecological examination. The use of artificial intelligence built into mobile devices offers a future for high quality diagnostics in resource-poor settings. By doing so, we will reduce the number of physical examinations and implement screenings by lower-level trained cadres. In addition, through a cost-effectiveness analysis and a business case for the global introduction of hrHPV testing as routine screening for cervical cancer, we will show the advantage of point-of-delivery testing and the benefits of self-testing for cancer in the post-COVID era, which reduces pressure on the health system. PRESCRIP-TEC will strengthen evidence of innovative strategies for cervical cancer screening
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Nanometrology Standardization Methods for Magnetic Nanoparticles' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The NanoMag project is to improve and redefine existing analyzing methods and in some cases, to develop new analyzing methods for magnetic nanostructures. Using improved manufacturing technologies we will synthesize magnetic nanoparticles with specific properties that will be analyzed with a multitude of characterization techniques (focusing on both structural as well as magnetic properties) and bring the experimental results together to obtain a self-consistent picture which describes how structural and magnetic properties are interrelated.  This extensive survey will be used to define standard measurements and techniques which are necessary for defining a magnetic nanostructure and quality control. NanoMag brings together Europe’s and internationally leading experts in; manufacturing of magnetic single-core nanoparticles and magnetic multi-core particles, analyzing and characterization of magnetic nanostructures and national metrology institutes. In the consortium we have gathered partners within research institutes, universities and metrology institutes, all carrying out front end research and developing applications in the field of magnetic nanoparticles.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Automating knowledge extraction from large dermatopathological datasets to establish objective and interpretable diagnostic frameworks' in the context of a Horizon Europe call.

assistant: **Objectives**

The continuous and overwhelming increase in the amount of data in health and science, including image collections, textbooks and scientific literature, renders it difficult to meaningfully understand, validate and query the available body of knowledge. Modern developments in artificial intelligence hold promise to solve these shortcomings by enabling the collection, understanding, curation, use of, as well as interaction with, large bodies of data. The goal of this project is to make this case in the explicit context of a highly specialized scientific field, dermatopathology, which is in charge of obtaining reliable diagnoses of skin diseases. We aspire to improve understanding in four different settings: 1) Unstructured real-life data: To obtain population-scale structured knowledge on the real-life burden of skin disease beyond cancer, we will use modern language models to automatically map historic unstructured pathology reports to disease entities. 2) Scientific corpora: Guidance of general-purpose language-models will be used to transform medical scientific corpora towards an open knowledge graph. 3) Cross-modality entity representation: Training a long-tail multi-modal and multi-task foundation model with enable to objectively define diagnostic grey zones and narrow them. 4) Interaction with large image data: Retrieval-, annotation-, and language-based interaction modalities will be developed into a digital microscopy viewing interface to find the most efficient avenues in human-computer interaction for the analysis of large-size medical image data. In sum, this project employs a multifaceted approach to standardize pathways to understand large,  multi-modal open-set data, and further explore further the field of human-computer interaction in highly specialized im
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The Global Sites of International Criminal Justice' under Horizon 2020.

assistant: **Concept**

JustSites studies the multitude of localities in which international criminal justice is produced, received and has impact. Building an innovative scientific vocabulary, the project understands these justice sites to be social topographies in which the political, legal and professional activities that collectively create international criminal justice are developed. The justice sites include locations in which forensic exhumations are carried out, NGO offices in conflict zones, foreign ministries, private law firms, media outlets, academic research centers, and the international criminal courts. These sites are closely related, and all depend on and compete with each other to define the direction of international criminal justice. With its analysis of justice sites, the project moves beyond the conventional focus on courts and their context to investigate instead the balances of authority and power that affect the relations between these topographies and thus drive the development of international criminal justice as a field of law. To investigate the relational topography of justice sites, the multidisciplinary project analyzes how these sites produce international criminal justice ideas and practices, and how such ideas and practices are received and have impact in other sites. By following the impact of ideas and practices as they move from one site to another, the relative and perceived authority and power of these sites will be identified and analyzed. Through their productive and receptive character, the justice sites also communicate the results of international criminal justice to broader audiences, labelling them in the process as a success or a failure. Therefore, contributing the first investigation of the topography of justice sites is not only of significan
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Coordinated Asia-European long-term Observing system of Qinghai – Tibet Plateau hydro-meteorological processes and the Asian-monsoon systEm with Ground satellite Image data and numerical Simulations'.

assistant: **Objectives**

Human life and the entire ecosystem of South East Asia depend upon the monsoon climate and its predictability. More than 40% of the earth's population lives in this region. Droughts and floods associated with the variability of rainfall frequently cause serious damage to ecosystems in these regions and, more importantly, injury and loss of human life. The headwater areas of seven major rivers in SE Asia, i.e. Yellow River, Yangtze, Mekong, Salween, Irrawaddy, Brahmaputra and Ganges, are located in the Tibetan Plateau. Estimates of the Plateau water balance rely on sparse and scarce observations that cannot provide the required accuracy, spatial density and temporal frequency. Fully integrated use of satellite and ground observations is necessary to support water resources management in SE Asia and to clarify the roles of the interactions between the land surface and the atmosphere over the Tibetan Plateau in the Asian monsoon system. The goal of this project is to: 1. Construct out of existing ground measurements and current / future satellites an observing system to determine and monitor the water yield of the Plateau, i.e. how much water is finally going into the seven major rivers of SE Asia; this requires estimating snowfall, rainfall, evapotranspiration and changes in soil moisture; 2. Monitor the evolution of snow, vegetation cover, surface wetness and surface fluxes and analyze the linkage with convective activity, (extreme) precipitation events and the Asian Monsoon; this aims at using monitoring of snow, vegetation and surface fluxes as a precursor of intense precipitation towards improving forecasts of (extreme) precipitations in SE Asia. A series of international efforts initiated in 1996 with the GAME-Tibet project. The effort described in this proposal buil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Advanced Carbon Capture for steel industries integrated in CCUS Clusters' (C4U) targeting Horizon 2020.

assistant: **Abstract**

C4U is a holistic interdisciplinary project involving the collaboration with 8 European countries and Mission Innovation Countries, Canada, China and USA aimed at addressing all the essential elements required for the optimal integration of CO2 capture in the iron and steel industry as part of the CCUS chain. This spans demonstration of highly efficient CO2 capture technologies at TRL7 designed for optimal integration into an iron and steel plant and detailed consideration of the safety, environmental, societal, policy and business aspects for successful incorporation into the North Sea Port CCUS cluster.The above involves the elevation from TRL5 to TRL7 two highly energy-efficient high-temperature solid-sorbent CO2 capture technologies for decarbonising blast furnace gas and other carbon containing gases. In addition, the C4U project  assesses the societal readiness and analyses the optimal design for full-scale integration of such technologies in industrial plants operated by the world’s largest iron and steel manufacturer, ArcelorMittal. For the first time, in combination, these two technologies will target up to 90% of the total emissions from the steel plant that come from a variety of sources. Using a whole system approach, we account for the impact of the quality of the captured CO2 on the safety and operation of the CO2 pipeline transportation and storage infrastructure whilst exploring utilisation opportunities based on integration into the North Sea Port CCUS industrial cluster. A candidate for the fourth Union list of Projects of Common Interest2, CO2TransPorts aims to establish the necessary infrastructure to facilitate the large-scale capture, transport and storage of CO2 from three of the most important ports in Europe; North Sea, Rotterdam and Antwerp and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'The European Schools Treasury Browser'.

assistant: **Objectives**

To build a Web educational resource Metadata Networking infrastructure for schools in Europe, to link together existing nationalrepositories, encourage new publication, and provide a reliable level of quality and structure. To add value to these systems by an interoperable layer to help teachers and students locate resources Europe-wide through a Schoolnet Information Space with rules to facilitate location of relevant resources. The user wants access to all data repositories, whatever indexing method is used. The user should only obtain all the most relevant resources for his own information needs. This rich information space can become a vast source of educational material classified according to subject and resource type for use by teachers in preparing e-lessons, and by students for reference and research, or guidelines and best practice. To reduce heterogeneity by harmonisation and measures for multilinguality.Work description:Architecture Elements: The key to success will be the ease of use of tools for publishing resources in the information space and for locating relevant information in that space. It is paramount that the development take into account existing national systems and technical infrastructures available within the schools. It is therefore assumed that material is published at the schools or through national or regional repositories. It is the metadata describing the resources, and the multilingual subject classification and thesaurus that underlie the proposed European Treasury Browser system. At the technical level the planned components are as follows.1) A Web enabled multilingual educational subject classification and thesaurus to aid accessing and providing content.2) An intelligent data-entry system for the end-user including a metadata author
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Twin Wind tunnels for Energy and the EnvironmenT - Innovations and Excellence' under Horizon Europe.

assistant: **Concept**

TWEET-IE aims to upgrade the Wind Tunnel (WT) testing activities of the widening member National Technical University of Athens (NTUA). The NTUA WT will be rendered on par with other world class facilities for hosting a variety of research applications in the field of external aerodynamics, primarily focusing on clean-tech, energy and transport applications. TWEET-IE is conceptually based on three distinct pillars i) enhancing administration and management capacity, ii) upgrading technical competence and iii) improving visibility and profile of the facility. It includes knowledge transfer and networking activities with 4 leading European universities, which have all been successfully operating their own large WTs for decades and have remarkable scientific and research track records.Renewable energy sources, clean-tech and energy efficiency in the urban environment will be the cornerstones for accomplishing EU’s energy and climate ambition to render Europe the first energy neutral continent by 2050 and WT experiments are indispensible for analyzing issues related to wind energy and environmental flows. This is one reason that upgrading the in-house WT has been prioritized as a research goal of paramount importance for both the School of Mechanical Engineering, NTUA and the labs involved in the WT management and operations.TWEET-IE’s primary goals will be achieved through systematic work and seamless communication between project working groups, comprising key personnel from all partners, and a series of networking, training and research activities and events, in which all leading members of the consortium play an equally important role. TWEET-IE’s strategic research goal is to address the challenge of measurement conformity among different WT. Four identical state-of-the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Chickpea as a potential source of high-quality protein for food formula' (CHICKFOOD) targeting Fifth Framework.

assistant: **Abstract**

Nutritional quality of seeds has been determined according to growing practices (irrigation)Different varieties of seeds have been selected in function of the content, their yield and their adaptation to the climatic conditions. A process for protein extraction has been developed but leading to a price four time the one of soya extract.The protein functionality has been studied leading to the conclusion that the functional performance is poor and not commercially viable purely as foaming emulsifying and gelling agent but may be used a as forming an active ingredient in more complex applications such as bakey or textured protein products developped by two of the industrial partners. Saponins were found to have potential interesting applications. STMS markers linked to seed weight and carotenoid content traits have been identified.