RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Arousal, cortical signal-to-noise, and the ability to sustain attention' in the context of a Seventh Framework call.

assistant: **Objectives**

Sustained attention or the ability to maintain an alert, goal-directed focus is critical for many levels of human behavior. Failures of sustained attention occur when there is a transient decrease in endogenous control of behavior leaving one prone to goal-neglect and distraction by irrelevant stimuli. Frequent lapses in sustained attention are a core feature of performance in the elderly, sleep-deprived individuals, and patients with brain injury and mental disorders with attentional components, such as attention-deficit hyperactivity disorder and schizophrenia. Even healthy individuals differ substantially in their ability to sustain attention. Recent studies have linked deficits in sustaining attention to less stable (i.e., more noisy) cortical signals in particular in frontal brain areas. Although recent research has shed light on the neural mechanisms underlying lapses of attention, less is known about how an individual’s ability to sustain attention might be improved. This knowledge is clearly imperative for the development of interventions that can address sustained attention deficits in patients or for individuals who are prone to attentional lapses due to e.g., disturbed sleeping patterns. The aim of this research project is to study the neural and neurochemical mechanisms underlying the ability to maintain an alert, goal-directed focus, and the effects of an alertness training strategy on this ability. We propose to conduct three studies that will test our main hypothesis that increased volitional control of arousal during sustained attention task performance will enhance cortical signal stability, and thereby attentional stability. The third study will examine the effects of the noradrenergic agonist clonidine on the hypothesized interaction between arousal a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Centre of excellence in power electronics and intelligent control for energy conservation (PELINCEC)'.

assistant: **Concept**

The Centre will promote research and disseminate knowledge on multi-disciplinary area of power electronic semiconductor devices, converter topologies and control systems with special emphasis on novel intelligent control issues for energy conservation, active filtering of line harmonics injected by non-linear loads and renewable energy sources. The Centre will be a technological bridge between European Community and east European countries including newly independent states.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Asymmetric Cell Division Imaging with Quantum Dots' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

During development, the genesis of daughter cells with different fates is established by asymmetric cell division, a highly conserved mechanism for the segregation of specific cell-fate determinants.A central issue in the field of cell biology is to identify specifically the mechanisms that govern cell diversity through asymmetrical partitioning of these determinants. In this project we propose to follow in real time the path, movements and interaction of two key proteins involved in the asymmetric division of Drosophila neuroblasts.Using single molecule fluorescence microscopy, targeted semiconductor nanocrystals (quantum dots) and various genetic neuroblast mutants, we propose to follow the intracellular routes and determine the spatial and temporal requirements of the cargo protein Miranda and its associated molecular motor Myosin VI.Through a multidisciplinary approach, we will stoichiometrically label Miranda to quantum dots and develop a GFP-based high affinity molecular marker for the targeting of t he nanoprobes to Myosin VI in the cytoplasm of neuroblasts. Following cell injection, we will perform high speed and multicolour imaging to track the diffusing single proteins in three dimensions.The developments proposed in this project will not only provide new information on the mechanisms of asymmetric division, but will also offer new approaches and new tools to the fields of optical microscopy, cell biology, and nanomaterials.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Luminescent polymers for in vivo imaging of amyloid signatures' in the context of a Seventh Framework call.

assistant: **Objectives**

In this project we seek to develop new smart imaging molecular tools for combating neurodegenerative diseases such as Alzheimer’s disease and prion diseases. Emphasis is put on translational applied research for the development and validation of novel properly functionalized luminescent conjugated polymers (LCP) that via modern imaging technology can give rise to entirely new and innovative methodology for studying neurodegenerative diseases. The objectives include the development of novel imaging agents that can be utilized for biomedical research, diagnosis, monitoring and prognosis, and for support and guidance of therapeutic interventions for Alzheimer’s disease and prion diseases. The consortium is composed of expert groups in experimental optics, polymer synthesis, magnetic resonance imaging (MRI), synthesis of functionalized magnetic nanoparticles, amyloid structure, AD mouse models, clinical AD, and prion diseases. At the same time this project establishes strategic links between mainly SME based Industries, expert researchers at universities and principal users in terms of hospitals. The project consortium will develop and share an efficient plan for dissemination and exploitation of the project results.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Dissecting the molecular mechanisms underlying hnRNP exclusion from DNA double-strand breaks.' (2021-2027).

assistant: **Concept**

DNA double-strand breaks (DSBs) are toxic lesions that must be efficiently repaired to maintain genome integrity. Following DNA damage, cells activate a multi-layered signalling and repair network termed the DSB response. Emerging organizers of this DSB response are various RNAs and RNA-binding proteins, which display characteristic localization dynamics at the damaged-chromatin. The laboratory of Stephanie Panier recently showed that many heterogeneous nuclear ribonucleoproteins (hnRNPs) are actively excluded from damaged chromatin soon after the induction of DSBs. The exact purposes of hnRNP exclusion and the underlying regulatory mechanisms remain to be determined. In my postdoctoral project, I propose to study why and how hnRNPs are excluded from damaged chromatin. To this end, 1) I will characterize the exclusion properties of the hnRNPs at DSBs using cellular models and unique genetic and microscopy approaches. 2) I will also identify protein and RNA complexes associated with hnRNPs at DSB sites using proximity labelling proteomics and RNA-sequencing approaches. In studying these hnRNPs, I will unravel the new mechanisms by which RNAs help to organize the DSB response. The combination of state-of-the-art cell biological and omic approaches will enable me to go well beyond the current knowledge of the field to characterize novel factors and mechanisms that coordinate RNA biology at DSB sites. Since genome instability and defects in RNA metabolism are both directly linked to the pathogenesis of cancer and also neurodegeneration, my findings will have direct implications for human health.


**Keywords:** Genetic instability, DNA double-strand break response, hnRNPs, RNA, RNA-binding proteins
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Nanosystems: Architectures, Design and Applications'.

assistant: **Innovation**

Nanosystems are integrated systems exploiting nanoelectronic devices. In particular, this proposal considers silicon nanowire and carbon nanotube technologies as replacement/enhancement of current silicon technologies. This proposal addresses high-risk, high-reward research, unique in its kind. The broad objective of this proposal is to study system organization, architectures and design tools which, based on a deep understanding and abstraction of the manufacturing technologies, allow us to realize nanosystems that outperform current integrated systems in terms of capabilities and performance. Thus this proposal will address modelling of technological aspects, synthesis and optimization of information processing functions from high-level specifications into the nanofabric, and new design technologies for specific aspects of nanosystems including, but not limited to, sensing and interfacing with the environment. This proposal will address also cross-cutting design goals such as ultra-low power and high-dependability design, with the overall objective of realizing nanosystems that are autonomous (w.r. to energy consumption) and autonomic (i.e., self healing). The scientific novelty of this proposal stems from the use of a nanofabric, where computation, sensing and communication are supported by a homogeneous means as well as from the study of algorithmic tools for mapping high-level functions onto the nanofabric. The intrinsic benefit of this research is to provide a design flow that extends both the technological basis and the capabilities of integrated systems, thus strengthening the industrial European position in a key sector where disruptive innovation is key for survival. The extrinsic benefit of this research is to broaden the use of nanosystems to new domains, in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'PhotoCloth: A framework to synthesize real-time photorealistic cloth animation from video input.' (PhotoCloth).

assistant: **Innovation**

Computer Graphics is the area of computer science that studies methods for digitally synthesizing and animating visual content. Among all the potential contexts where computer graphics techniques can be used, cloth animation is a particularly interesting case since, in the real world, clothing is far more than just the physical objects that we wear; clothing is a key element to show someone’s expressiveness and motion, it even defines his or her identity. However, cloth animation is a complex and extremely high-dimensional problem. To digitally synthesize cloth animation, a large number of properties that affect the way cloth behaves need to be estimated: textures, deformations, collisions, materials, illumination, etc. Current approaches for cloth animation tried to overcome this challenging problem following two main trends: image-based methods use captured data to construct a low-dimensional model to digitally synthesize new animations, however they can only sample a small portion of the high-dimensional space of cloth and poses; the physics-based methods aim to simulate cloth only using mathematical equations that express physics laws, however, they are computationally expensive and have trouble replicating real-world behavior. This fellowship will investigate a new  model for cloth simulation that combines a physical-based method with image-based infomation to generate real-time believable cloth animation. The new model will use a multi-scale framework to handle the dynamic geometry and appearance at different levels of detail. The most salient dynamic geometric properties of the animation will be handled by a low-resolution representation of the cloth using a physics-based model, which reduces the high-dimensionality of the pose space to a lower-dimensional subspa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Hybrid AIRcraft seating requirement specification and Design' (HAIRD) under Horizon 2020.

assistant: **Objectives**

HAIRD project aims to deliver a new design for a next generation aircraft seating which is comfortable,light-weight, fast to disassemble, easy to dismantle, cost efficient to produce, highly recyclable and reliable in structural integrity. Within the HAIRD project a new mono-materials cushions will be developed to improve the easy-recyclability and the cost production. Topological and geometrical optimization techniques will be applied by means of computational tools to ensure weight reduction without compromising the structural reliability. This approach will be used in both structure and cushions combined by selection of very light-materials in the market. A new mechanical system also will be designed allowing fast assembly, dismantling and disassembly of the seat into the aircraft, shortening the maintenance cost and workforce. Finally an assessment of seating Life-cycle will be done to guarantee the new design improvement in terms of sustainability. The direct impact is expected in terms of sustainability, economical viability, novel attractive, cost reduction in maintenance and material, fuel consumption and CO2 emissions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Cost efficient thermal management in motors using next generation nanomaterials', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Electric motor drives are the universal work horses of industry driving fans, pumps, power tools, compressors and materials handling/conveyor systems. More energy efficient motor designs are needed to meet increasingly stringent EU efficiency standards.  Better thermal management of electric motors could make this achievable.  Current technologies rely on expensive copper casings or inefficient air cooling.  Adding more copper is not feasible (bigger, heavier and expensive) and liquid cooling is not attractive (more energy for circulation/maintenance). The extra mass/volume cannot be easily integrated in compact motor layouts. Removal of heat from small totally enclosed motors is a recurring problem in the food processing, surgical instruments and materials handling where the motors operate at their limits and run very hot. An improved method of cooling could be engineered from advanced materials. Nanomaterials such as carbon nanotubes are at least six times more thermally conductive than conventional thermal interface. A commercial application using specially tailored carbon nanotubes (CNTs) for the development of energy-saving, highly efficient motors is the aim of CONDUCT in partnership with an EU SME motor design/manufacturer.  Results of CONDUCT will feed into advanced automotive, consumer, and power electronics industries who also need to find solutions for similar challenges in thermal management.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Reconfigurable Systems for mobile local communication and positioning'.

assistant: **Innovation**

RESOLUTION aims at developing of a wireless three-dimensional (3-D) local positioning system with measurement accuracy in the centimetre regime and real-time ability. A novel frequency modulated continuous wave (FMCW) radar principle with pulsed active reflector is employed. This advanced local position radar (ALPR) will be implemented on basis of common WLAN systems.Due to its high data rate capabilities and large potential bandwidth, the 802.11a/n standard allocated around 5.5 GHz is applied. Special care is put on the reconfigurability by efficiently using inherent synergies between the WLAN system and the ALPR approach. Thus, the additional costs compared to standard WLAN systems are reduced to a minimum. To allow multifunctional tasks, highly integrated system on chip (SoC) frontends will be designed on advanced CMOS or BiCMOS technology. Smart power and adaptive performance control will be applied to minimise the power consumption according to application needs. In order to enhance the performance and coverage range, the transceiver features adaptive antenna combining in the radio frequency (RF) receiver. Compared to conventional approaches performing adaptive combining in the baseband, this approach significantly decreases the power consumption, size and costs, since the number of multiple components is reduced to a minimum.Because of the high 3-D resolution and real-time ability, which can even be achieved in indoor environments with strong multipath effects and fading, novel local positioning applications, e.g. for smart factories, robotics, guiding, object tracking and augmented reality are possible leading to a large economic potential. Market analyses and preparations for a market launch are performed to allow a successful exploitation of the results. The co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Sustainable Training of Code Language Models through Data Refinement' under Horizon Europe.

assistant: **Concept**

Large language models (LLMs) have gained widespread attention and user adoption. These models, when trained on source code from platforms like GitHub, acquire a deep understanding of both the semantic and syntactic structures of code (i.e., code language models or CLMs). This understanding has paved the way for significant advancements in software engineering, offering developers valuable assistance in labor-intensive tasks like bug fixing and code writing. While CLMs offer tremendous assistance in software engineering tasks, their massive data requirements result in substantial energy consumption and CO2 emissions.This proposal challenges the conventional wisdom that ""more data is better"" and instead advocates for a refined approach to data in the training of CLMs. We propose that by intentionally decreasing training data volume while simultaneously enhancing data quality through data refinement techniques, we can reduce energy consumption while maintaining or even improving performance on software engineering tasks. The condenSE project represents a pioneering effort to advance sustainable training practices for CLMs. Unlike existing methods, which are often non-systematic or limited to natural languages, condenSE promises a comprehensive approach to achieve sustainability via data refinement for CLMs.This initiative is well-aligned with the EU Green Deal initiative and UN Sustainable Development Goals, and the increasing attention for LLMs and CLMs means that now is the right time to address their sustainability. The proposal's potential for success is further strengthened by the host institution's international standing, providing a wide range of collaborative opportunities, as well as by the complementary expertise of the applicant and supervisor, spanning the fi