RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Computational Models for new Patients Stratification Strategies of Neuromuscular Disorders' under Horizon Europe.

assistant: **Concept**

The CoMPaSS-NMD project creates novel and universal tools for the diagnostic stratification of patients suffering from Hereditary NeuroMuscular Diseases (HNMDs) aiming at personalised treatments. HNMDs often occurs in young people, causing long-term disability and early death; these conditions bring lack of participation, need for permanent assistance and may require long-term institutionalisation. Multidimensional HNMD data - clinical, genetic, histopathological and MRI – will be provided by third-level clinical centers in Italy, France, Germany, Finland and the United Kingdom as part of the European Reference Network for Rare Neurological Diseases. Computational tools for high-dimensional clustering will be applied in an unsupervised learning approach using the internal structure of data to define groups of similar patients. Classification model averaging and integration techniques for federated learning-inspired model building and novel HNMD-specific descriptors of histopathological images will be implemented. The adoption of this multidimensional view has the potential to increment the diagnostic rate of HNMDs by 30% and foster effective actions by European national health systems.As main project outcome, the CoMPaSS-NMD Atlas Platform will be a cost-effective AI-based application providing precise clinical characterization and diagnosis, with data remaining publicly available for anyone in the research and health community to use. The project will deliver Recommendations and Guidelines for stratification-based patient management to offer superior standard-of-care for diagnosis and prognosis and assist in planning clinical trials. It will follow a user-centred, co-design methodology with a strong stakeholder engagement and networking with other project consortia.The
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Postgraduate School of Industrial Ecology'.

assistant: **Concept**

Industrial Ecology is an emerging field that addresses the current problems in finding a balance between economic development and environmental protection. Europe now has several universities with strong research programs in Industrial Ecology. Universitie s in the new EU member states wish to build up their research capacity in the field. These research programs are undergoing rapid growth as the need for specialists in sustainability issues becomes increasingly evident. It is important to develop and unify the field of Industrial Ecology across Europe to allow implementation of policy measuresinitiated by the EU. This is particularly true for the new EU member states which face rapid economic development.Industrial Ecology uses scientific methods such as li fe-cycle assessment and material flow analysis to advance sustainable production and consumption. Through ecological design and life-cycle management, it contributes to achieving sustainability at a corporate and administrative level. Industrial Ecology is directly relevant to the EU's sustainability targets and initiatives, including the EU's commitments to sustainable production and consumption at the World Summit for Sustainable Development, Integrated Product Policy, and the Kyoto Protocol. It is propos ed to develop a series of training courses for early stage researchers called the Postgraduate School of Industrial Ecology. Seven training courses are proposed, six of which will be hosted by universities in the new EU member states in Central and Eastern Europe. These countries face immediate environmental and social pressures from economic growth and research expertise in Industrial Ecology needs to be developed rapidly. The course lecturers come from established research programs in Industrial Ecology a cros
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Flexible Dimensionality of Representational Spaces in Category Learning', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Our visual system frequently has to classify complex, high dimensional inputs. A key learning objective of the brain is thus to identify diagnostic dimensions. Often, tasks require simultaneous consideration of multiple dimensions. Yet, learning many dimensions is computationally challenging. Here, I ask how the visual system tackles the challenge of learning high dimensional tasks. Some theories suggest that the brain does so by compressing dimensions, while others suggest dimensionality expansion. Yet, dimensionality compression and expansion both have advantages and disadvantages, and some studies find dimensionality compression where others find expansion. This raises the hitherto unanswered question what determines whether the brain invokes either of the two strategies. I hypothesize that instead of settling on a single strategy, the brain can reap the benefits of dimensionality compression and expansion by flexibly adjusting dimensionality to the task at hand. This entails the novel prediction of flexible neural codes that can switch dimensionality. To test this theory, I build on a multimodal, multispecies approach I have developed to study learning: using the paradigmatic case of visual category learning, I will establish the effect of task dimensionality on the structure of mental representations in behavior, I will determine how task dimensionality transforms neural activity using neuroimaging in humans, I will identify the neural building blocks of flexible dimensionality using electrophysiology and causal perturbations in rhesus monkeys, and I will unravel computational principles of flexible dimensionality with artificial neural networks. This combination of species and techniques is ideally suited to unravel the neural mechanisms for coping with high dimen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'MIcro- and NAno-Plastics in AGRIricultural Soils: sources, environmental fate and impacts on ecosystem services and overall sustainability' (MINAGRIS) targeting Horizon 2020.

assistant: **Abstract**

Plastic use in agriculture has tremendously increased in the past decades resulting in soil pollution with plastic residues forming besides macroplastics micro (MP) and nanoplastics (NP). MINAGRIS aims to contribute to healthy soils in Europe by providing a deeper understanding and tools to assess the impact of MP and NP in agricultural soil health. To create an overview on the actual situation across Europe, MINAGRIS will assess the use of different plastic polymers in agricultural systems in 11 case study across Europe and identify the resulting types and concentrations of MPs and NPs. Concentrations of other stressors in soils such as pesticides and veterinary drugs will be additionally assessed. MINAGRIS will provide validated analytical tools that allow the quantification and identification of MPs and NPs in soils.Based on the results of the case study sites, controlled experiments will be conducted to analyse the impact of MPs and NPs on physico-chemical soil properties, soil biodiversity, plant productivity, and Ecosystem Services, as well as their potential transfer to other parts of the environment and plants. Furthermore, synergistic effects with other stressors are assessed.Quantification of the impacts of MNP on soil biodiversity and agricultural productivity, their transport and degradation in the environment, their impacts on socio-economic components, and synergies between all of them will make it possible to identify, in a multifactorial vision, the benefits and risks associated with the use of plastics in agriculture.Based on the results, MINAGRIS will quantify the economic, environmental, and social consequences of unsustainable soil management at the field and farm level in different biogeographical regions and, through a Multi-Actor Approach (MAA), d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Application of biofuel by-products to the soil: implications for Carbon Sequestration and GHG Emissions' (BEST).

assistant: **Concept**

Biofuel production is considered a promising strategy for reducing the net emissions of CO2 into the atmosphere and decreasing dependence on fossil fuels. Hence interest in energy production from renewable biomass is increasing worldwide. However, biofuel production also implies a decrease in the return of carbon (C) rich crop residues to the soil, which is replaced with nitrogen (N) rich by-products of biofuel production (BBPs). This may profoundly affect the greenhouse gas (GHG) balance of the soil, both through a decrease in the soil organic carbon content (CO2 emission), and through an increase in N2O emission from mineralized N. However, no scientific data is available to quantify this effect. Research on the effects of biofuel production on the GHG balance of the soil is therefore needed to complete the life cycle analysis (LCA) of biofuel production. The aim of this proposal is to quantify the effect of BBPs applied to the soil on GHG emissions and related N and C dynamics in the soil. We will work with by-products of the three main bioenergy chains: (i) bioethanol from wheat; (ii) biodiesel from rapeseed; and (iii) biogas from anaerobic digestion of silage maize. In a series of laboratory incubation experiments, the C and N mineralization of the various BBPs will be assessed in relation to crop residue and N fertilizers. The fate of C from crop residue and BBPs in the soil organic matter fractions of increasing stability will be quantified using 13C tracing. The combined effect of changes in SOC and N2O emission will be expressed in terms of global warming potential to complete the LCA of the various biofuel chains.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Molecular epidemiology of hiv-1 intersubtype recombinant strains' (1998-2002).

assistant: **Innovation**

Extensive search of the prevalence of the HIV-1 subtypes and recombinants in Greece. Analysis of the complete full-length sequences of new HIV-1 recombinants. Molecular epidemiology of the parental fragments and dating the origin of recombination events
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'e-Solar Performance Analysis and data Collection for Energy Monitoring: an innovative solution based on measures correlation between an autonomous ground-based solar sensor and Earth observation data'.

assistant: **Concept**

Is a solar installation working at its full potential or not? This question is more frequently asked these days either by solar farms operators, venture capitalists willing to invest in renewable energy or companies specialized in operations and maintenance. Comparing irradiance data observed from the ground with data coming from relevant geostationary satellite should provide the answer. e-SPACE Monitoring aims at delivering PV operators with a permanent PV performance assessment on line service. Through a SAAS platform, operators will access data based on measures correlation between a stand-alone ground-based solar irradiance measurement sensor and satellite data coming from geostationary meteorological satellites completed by Sentinel 4 & 5 satellites and Copernicus services.By using data analysis algorithms, e-SPACE Monitoring’s personalized service will be able to point out discrepancies between the solar data measured on site and the plant’s actual solar production. This information will be used by plant operators to set up personalized Key Performance Indicators showing whether a solar installation is working at its full potential or not and improve the Operations & Maintenance of their PV installations.In the coming years, e-SPACE Monitoring will enable REUNIWATT to take advantage of the tremendous growth of the installed solar base worldwide and resulting PV monitoring market. REUNIWATT has a huge opportunity to market a service that will benefit thousands of solar operators globally and contribute to the development of solar power efficiency.The commercialization of the e-SPACE Monitoring will make REUNIWATT the first European company and a worldwide leader in this field with an estimated turnover of about 20 million euros and the creation of 35 new high-leve
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Availability of machinery in the plastics industry by effective reliability engineering' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The aim of this research is to develop condition monitoring and knowledge based expert systems for the plastics processing industry to give advanced warning of impending failure of machinery so that maintenance or other corrective action cane scheduled before failure occurs. The objectives are to reduce breakdowns and overall operating costs by 20 %, extend the operating life of machines by 10 %. At least 10 % of the overall maintenance costs in plastics processing companies will be cut (that would mean an annual saving to the EU of 240 million EURO). These objectives will be achieved within two years of the project completion. Ten companies from France, and Spain will join this project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Process for biological decomposable self-standing plastic-bags' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

There are different possibilities for transport and storage of liquid and powdery materials like colour, cleansing agent, food or medical infusions. For example plastic bottles, metal buckets or plastic bags. Self standing plastic bags are especially suitable for packaging these materials because they are extremely light, have a small waste-volume and of cause they are 'self standing' after filling. Therefore self standing plastic bags are especially suited as refill-package. A transfer to applications in mass like packages couldn't be realised up to now. Our research goals are to develop further biodegradable an biological decomposable plastic materials for use in plastic-bags, to realise a production method and machine technology to produce self standing plastic bags out of the new ecological well tolerated material, to develop technologies to produce plastic bags with an integrated relockable scip-out, existing of the same biological decomposable material as the self standing plastic bag and to realise an integrated system to produce the complete bag in one production-step (foil-production, welding, integrating the scip-out, cutting, quality controlling and filling). The research is to be cooperative, both partners don't have the necessary development-resources or expertise to carry out the research.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'The molecular mechanisms of axon re-extension following developmental axon pruning' (2007-2013).

assistant: **Innovation**

Lack of neuronal regeneration following injury such as spinal cord injury is the major cause for poor functional recovery. It has long been appreciated that young neurons can grow, undergo reorganization and synapse on appropriate targets during development while adult neurons cannot, however the molecular basis of these differences remain unclear. Studying the molecular mechanisms that regulate axon re-extension following remodeling during development holds the promise to uncover molecular rules underlying this phenomena and are therefore of great potential. A model system that allows a unique molecular exploration of axon re-extension is that of axon pruning in Drosophila. Pruning is a process in which neurons first extend excessive branches, later prune away inappropriate ones with precise spatial and temporal control and, at least in the some cases, re-extend their axons to form mature connections. Pruning was found to essential for sculpting the mature nervous systems of vertebrates and invertebrates. During my post-doctoral studies, I performed a mosaic screen and identified a mutant exhibiting normal pruning but lacking the stereotypical axon re-extension that follows. Remarkably, other neurons, belonging to the mutant clone but which do not undergo pruning, extend their axons normally at the same developmental time, indicating that the mutation selectively affected axon re-extension following pruning but not axon extension per se. This novel finding suggests that there is molecular switch dedicated to changing the growing status of a neuron. The causal gene was mapped to an uncharacterized steroid hormone receptor, HR51. Here, I propose to characterize the role of HR51 in axon re-extension as well as identify its ligand. In addition I propose to perform a suppre
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Detection and multimodal presentation of indoor objects for visually impaired people'.

assistant: **Objectives**

The World Health Organisation states that one of 175 people is totally blind. The majority of these people are only mobile if they have help of others, or solely use known pace ways. Besides the cane with a limited range and an expensive guide dog, there are very few aids that support individual mobility of the visually impaired. Available assistant equipment and navigation systems based on GPS have some additional value to determine global directions, but are not able to deal with (moving) persons and obstacles, have a low accuracy and do not work indoors.This project will develop the stand-alone wearable RANGE-IT prototype, which detects and presents close range objects (<7 meter) to the user in any indoor space. Furthermore, specific reference points (e.g., stairs) will be identified. Based on individual needs and with respect to context, presentation of information will be in tactile and/or audio modality.RANGE-IT will be built using affordable components, taking advantage of the latest developments in tactile and 3D camera hardware and image recognition software. An iterative co-creation design process will be followed to ensure an optimal integration and user acceptance.The successful development of the RANGE-IT system will make it the first indoor stand-alone system in the world to assist blind persons in navigating through the environment. It will increase the individual mobility of visually impaired people and their participation in society.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'World's first device-based treatment for small abdominal aortic aneurysms based on revolutionary new treatment paradigm' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The Angiolutions device is a first-of-its-kind device stopping the life-threatening progression of small abdominal aortic aneurysm (AAA) – a pathological dilation of the aorta.Angiolutions’ award-winning & patent-protected solution leverages a fundamentally new understanding of AAA growth discovered by the founders at Stanford University. They showed that stiffness gradients between the compliant (healthy) aorta and the adjacent stiff (diseased) aneurysm serve as a motor for AAA growth.Based on this principle & together with key physicians, we developed a minimally-invasive, non-active aortic implant (class III). The nitinol-based device is positioned adjacent to the aneurysm sack via simple, catheter-based implantation. It is specifically designed to focally increase aortic stiffness in the compliant AAA neck region, thereby reducing stiffness gradients towards the stiff AAA sack that drive aneurysm growth.Hereby, we achieve a fast, low-risk, size-stabilizing treatment of small AAA.


**Keywords:** abdominal aortic aneurysm,healthy ageing