RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Mediterranean Information Society' in the context of a Sixth Framework call.

assistant: **Objectives**

The overall objective of MED-IST is to bring the Mediterranean Partner Countries closer to the European Framework Programme in the field of Information Society Technologies. This will be done through an open consultation process where the national bodies responsible for formulating their research strategy will come together with the active research community to review current research policies and develop appropriate guidelines in view of both their own needs and the IST priorities of FP7. This consultation process will not only result in recommendations for each MPC but also for the Framework priorities to take specific needs of the MPC into account. The final outcome will be recommendation guidelines for a strategic research agenda focusing on a closer co-operation between Europe and the MPC.Furthermore, MED-IST will target the research communities directly with active promotion events for the Framework Programme opportunities as well as by identifying suitable research organisations and IT companies in that region, training them on the procedural aspects and providing assistance in finding co-operation partners in Europe. In particular, focused mentoring workshops/tutorials will be organised in order to train the identified organisations on the procedures and opportunities for co-operation in the IST programme. The workshops will address the training needs and research & development capabilities of the MPC organisations.MED-IST will prepare a Directory of MPC Organisations" that will include research institutes, universities, IT companies, technology developers as well as independent researchers. This Directory will be one of the key elements in building new networks between Europe and the MPC.Finally, MED-IST project will develop an Internet Portal supporting all ac
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'ANISOTROPIC RESPONSE OF UNSATURATED SOILS: A MICROSTRUCTURAL APPROACH' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The expression “unsaturated soil” is used in geotechnical engineering to identify a class of soils whose pores are partially filled with water and partially filled with air. Unsaturated soils occur naturally above the water table as a superficial ground layer, whose thickness depends on the balance of precipitation and evapo-transpiration and, hence, on the prevailing local climatic conditions. Unsaturated soils also occur in manmade structures that are built by compacted earth such as embankments, gravity dams, barriers for underground nuclear waste repositories and flood defences. The engineering properties of unsaturated soils are therefore crucial to many civil engineering applications as well as to geohazards engineering (e.g. slope instabilities and landslides). The response of unsaturated soils to loading and environmental actions is crucially dependent on the mechanical anisotropy of this material. Anisotropy in unsaturated soils may be caused by two concurring factors, i.e. the nature of the soil fabric and the deviatoric component of the inter-granular stress generated by capillary pore water. This project aims at investigating anisotropy in unsaturated soils based on the appreciation of the microscopic interactions between solid grains, pore water and pore air. The research is divided in four main tasks: a) performance of laboratory tests on unsaturated soil samples compacted under different conditions to achieve different degree of initial cross-anisotropy, b) interpretation of test results in terms of theoretical models based on the mechanics of granular materials and continuum mechanics, c) microscopy analysis of soil samples subjected to cycles of wetting and drying and 4) study of boundary value problems where the anisotropy of unsaturated soils is parti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'SCATter computed TOmography of the Breast: in vitro" tests and assessment of clinical feasibility"' (B-SCATTO) under Sixth Framework.

assistant: **Objectives**

The research regards the application of computed tomography to breast scatter imaging for the design of a pre-clinical prototype. The technique is based on the possibility of discriminating normal and neoplastic breast tissue due to their different scattering properties. Hence, it is possible to obtain complementary information with respect to transmission imaging by detecting scattered rather than transmitted radiation.A combination of scatter imaging and computed tomography would provide images with both high contrast and three-dimensional information. Polychromatic and quasi-monochromatic X-ray spectra, the latter obtained by means of a pyrolytic graphite mosaic crystal, would be characterized and used. Images of test objects and of breast tissue samples would be acquired by means of a custom designed set-up, including an X-ray tube, a removable pyrolytic graphite mosaic crystal, a collimation system and a detection device, consisting of one or more detectors for transmission and scatter acquisitions.The most suitable configuration of the system for clinical applications would be determined depending upon image quality, acquisition time and delivered dose. CT reconstruction algorithms and registration techniques would be studied and compared by applying t hem initially to simulated data and later to acquired data. The research would provide the specifications for a pre-clinical set-up for in vivo imaging that would be designed at the end of the work.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'DNA: A Dependable NIC Architecture' (DNA).

assistant: **Innovation**

The DNA project aims to develop and deploy trustworthy distributed systems on large-scale heterogeneousdatacenters (HDCs) such that their dependability properties, i.e., safety, security, and fault-tolerance, can beenforced by the foundational layers of the network hardware stack.Distributed systems have become ubiquitous in modern cloud environments, offering high availability, perfor-mance, and resource scalability. However, ensuring the dependability and performance of distributed systems inlarge-scale HDCs, which are vulnerable to malicious threats and arbitrary (Byzantine) failures, is a complex task.Existing systems are limited by (a) programmability: They lack a unified, trusted foundation for security andprogrammability, (b) security: They have vulnerabilities and may be unable to handle malicious attacks and(c) high-performance: They can be slow, especially in complex distributed systems. These limitations forceprogrammers to use ad-hoc methods, which can be expensive and unreliable.The DNA project seeks to resolve the design trade-off between security and performance by introducing anew trustworthy network-level abstraction. DNA realizes this abstraction by proposing a minimalistic,high-performance, and verifiable silicon-root-of-trust as the foundational hardware building block forimplementing trustworthy distributed systems.Our implementation of DNA on commodity SmartNICs will revolutionize the way distributed systems arebuilt in cloud environments. By providing a synergistic co-design of hardware-software networking substrate,we abstract out the hardware heterogeneity in cloud environments while providing a minimalistic interfacefor resource management, isolation, communication, and trust establishment. Overall, we aim to empowerprogrammers and significantl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project '6th International meeting on Ribonucleases' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

6th International Meeting on Ribonucleases Pancreatic ribonuclease, the focus of highly productive scientific research for more than a half a century is the only enzyme to be the basis for four Nobel prizes. There is now resurgence in interest in this superfamily since members have functions ranging from tumour growth and inhibition to self -recognition and neurotoxicity. The proposed 6th International meeting on ribonucleases aims at gathering scientists from various parts of the World with an aim to stimulate interest, provide an overview, and discuss the future prospects into research on ribonucleases. In this context, we are grateful to the organisers of previous five international meetings on this topic (held every three years in different parts of the World) who share our conviction that the ribonucleases are important biological modulators that deserve the attention of the scientific community. We are hopeful about the active participation of the many ribonucleologists who have significant stories to relate in the meeting that we are intending to host in Bath (UK) from 19-23 June 2002. The meeting will certainly provide a forum for all those who have contributed to the field to discuss the functional diversity of ribonucleases.The programme content would involve six broad topics and should cover more or less all aspects of the fertile field of ribonucleases. They are:1. Function/s of Ribonucleases in health and disease.2. Structure and mechanism of Ribonucleases.3. Ribonuclease stability and folding.4. RNA degradation and processing.5. Applications of Ribonucleases.6. Emerging Ribonucleases, evolution and genomics.ftp://ftp.cordis.lu/pub/improving/docs/HPCF-2001-00167-1.pdf
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Vegetalising Ancient Architecture. A Multi-scalar Approach of the Relationship with Nature: Gardens, Vegetal Décors and Architecture in Gallo-Roman Sanctuaries (1st-3rd c. AD).'.

assistant: **Objectives**

Amid today’s environmental challenges, the long-standing Western divide between nature and culture is increasingly being called into question. Roman Antiquity, a significant period in our past, helps us reconsider such opposition. For the Romans, maintaining a harmonious relationship with ‘nature’ was essential to sustaining order and prosperity, as it was not a mere physical environment, but a subversive force, a realm intertwining the sensory with the divine. The use of real and iconographic vegetation in the living spaces was a central concern. The VegArch project aims to explore this vegetalisation within the specific context of Gallo-Roman sanctuaries of the 1st-3rd c. AD. From the penetration of Italic traditions to an unprecedented ‘hypervegetalisation’ of architecture, this greening has long been explained by a presumed persistence of Celtic naturalism or a mere decorative trend. Its role in shaping the experience of nature, the cosmos, and the divine can now be addressed with the expanding archaeological data and ecofacts and through an interdisciplinary approach. The vegetal forms will be gathered and compared in a trans-medial analysis, considering real and artificial forms as one and the same vegetal art and the sanctuary as a unitary system. This formal step will highlight the specificities of Gallo-Roman contexts in a global/local perspective. Through comprehensive and contextualised case studies, the vegetal forms will then be analysed in their spatial, temporal and sensory dimensions to reveal their polysemic value and how they engage the senses and shape the experience of the sacred. The resulting synthesis will contribute to the cultural history of vegetalisation of Western architecture, helping to unveil the relationship with nature in ancient societi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Biomimiking the brain - towards 3D neuronal network dynamics' (3DNeuroN).

assistant: **Concept**

Our view is that the biological and computational components and the concepts of realized BIO-ICT interactions have lacked so far the complexity of the actual high level biological neural systems. Our vision is that three key features are needed for biological computational neuronal networks: 1. Actual 3D structures of neuronal cells and networks, 2. interactions between various types of neuronal cells, and finally, 3. organized layered and patterned 3D microstructure of neuronal tissue.We aim to construct an in vitro model of a 3D neuronal network with layered biomaterial and multi-cell-type neural structure derived from human stem cells while stimulating and closely monitoring the evolution of cells and their connections. We will stimulate the novel 2D and 3D neuronal networks and layered structures also with modeled human auditory sensory inputs, and measure and model the responses and changes of the network topology and dynamics. With these we aim to reach the unproven concept of making the transition from neuronal 2D cultures to 3D controlled multi-cell-type neuronal structures in vitro that  mimic the actual in vivo 3D development of neuronal dynamics and finally to reach a deeper understanding on the function of human 3D neuronal networks such as the cortical column.The proposal is based on cellular, biointerface, bioelectronics, and ICT technology. Novel stem cell and biomimetic technologies provide us a way to grow different human neural cell types for 3D neuronal networks. Novel biomaterials, microelectronics, and ICT modeling will provide the control and analysis power to see the functional dynamics of the constructs.Our in vitro 3D model will provide a new level of elaboration. In addition to biological and clinical outcomes, the basic knowledge gained on th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Neurological evaluation with simple tools to track evolution and perform early detection of neurodegenerative issues' to be submitted under Horizon 2020.

assistant: **Abstract**

To the date there is no accurate scale to quantitatively measure motor dysfunction in neurological movement disorders. Doctors heavily relay on the information provided by the patients themselves. Objective data concerning the patient’s actual movements or seizures during their ordinary day would be very valuable for the doctors. The current common scales are only semi-quantitative, subjective and non continuous.  As consequence, one of the problems it implies is related to the reduction of sensitivity of clinical changes observed in clinical trials. In addition, there are no motor assessments that can be used to investigate the disease progression in pre-symptomatic subjects. In other words, today neurologists do not have a tool that allows them to know objectively if the patient has more or less shaking than last time. Movement disorders are comprised of a variety of conditions resulting in abnormalities in the motor system. These include such disorders as Parkinson's disease and other Parkinsonian syndromes, tremors, dystonia, tics , Tourette syndrome, Alzheimer's and Huntington's diseases. They can occur in all age groups from infancy to the elderly. In some cases, symptoms are restricted to problems in motor control while in others cases, cognitive and autonomic functions can be affected. mememtum provides a measuring tool and monitors progress of neurological patients and helps in early detection of certain disorders. Using image analysis techniques, the phone camera, screen and sensors, mememtum analyses and quantifies the state of the patient from a neurological and movement disorder point of view.Our product revolutionizes the way to measure neurological condition in a simple and accurate way:• Allowing remote patient tracking and evaluation of the movement dis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Gravity and Kinematic Space'.

assistant: **Objectives**

The experienced researcher, Dr. Benjamin Mosk, wants to investigate a description of gravity in terms of non-local degrees of freedom. This approach is motivated by the AdS/CFT correspondence and the recent progress made by Dr. Mosk and his collaborators on the subject of kinematic space, the space of totally geodesic sub manifolds of Anti de Sitter (AdS) space. Dr. Mosk proposes to generalize the idea of kinematic space and the description of dynamical fields on this space to more general classical geometries, starting with the AdS-Schwarzschild geometry. The scientific objective of this project is to make progress towards a fundamental description of gravity at the non-classical level, which is arguably the largest open question in theoretical physics.Dr. Mosk, who is currently conducting postdoctoral research at Stanford University, is applying for a Global Fellowship. During the outgoing phase, Dr. Mosk wants to go to UC Berkeley, where he will work with Professor Raphael Bousso. The return phase will take place at the University of Cambridge, where Professor David Tong is supporting his application. Both research groups have their specific specializations, which are complementary in the project and allow for a great degree of synergy and knowledge exchange between the partner organizations and the experienced researcher.Special emphasis will be put onto developing Dr. Mosk’s international network and visibility, which are key factors towards Dr. Mosk’s long term career goals. The proposal elaborates on the appropriate training necessary to reach these career goals. A MSCA Individual Fellowship (Global) would support Dr. Mosk’s professional development optimally, by enabling him to work in the perfect environment and by facilitating for the appropriate training desc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Aptamer nanostructures dual-targeted to the HER receptor family for cancer therapy' (ADHERE).

assistant: **Concept**

The proposed research programme deals with the development of aptamer nanostructures for targeted cancer therapy. Immunotherapy encompasses a growing field of anti-cancer therapeutics that target cancer cells expressing specific antigens, such as members of the HER receptor. Currently, immunoglobulins directed to HER1, better known as EGFR, and HER2 are used in the clinical management of several types of cancer. There are, however, several disadvantages associated with the production and application of immunoglobulins. Moreover, there is evidence that dual-targeting of multiple receptors at the same time is advantageous for improving clinical outcome and reducing drug resistance. Aptamers, which are short single-stranded oligonucleotides that can bind a target molecule in a similar fashion as immunoglobulins, may form, due to their physicochemical properties, a superior alternative strategy for targeted cancer therapy. In ADHERE, I will design (WP1) and investigate in vitro (WP2) and in vivo (WP3) the use of aptamer nanostructures with bispecific (against both EGFR and HER2) and multivalent (up to 4 binding ligands) targeting properties for cancer cell targeting.The 24-month research project will be executed at the department of Polymer Chemistry and Bioengineering at the Zernike Institute for Advanced Materials, University of Groningen, The Netherlands. The aim of this MSCA IF fellowship is to integrate my extensive background in targeted drug delivery and cellular therapeutics within the host institute, which is highly experienced with DNA nanomaterials and is positioned among the top 10 institutes of the world in the field of material science. Importantly, this fellowship will strengthen my career perspectives, by allowing me to gain valuable new transferable skills