RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'SAtellite-based Signalling and Automation SysTems on Railways along with Formal Method and Moving Block validation'.

assistant: **Innovation**

The ASTRail project falls within the scope of the topic S2R-OC-IP2-01-2017 – Operational conditions of the signalling and automation systems; signalling system hazard analysis and GNSS SIS characterization along with Formal Method application in railway field, which is connected with the complementary topics S2R-CFM-IP2-01-2015 and S2R-CFM-IP2-01-2017.The ASTRail project will act to enhance the signalling and automation system by searching innovative solutions that exploit cutting edge technologies already present in sectors different from the rail such as the avionics or the automotive sector. Investigation of such technologies and assessment of their reusability in the railway field will be done taking in particular care all issues related to safety and performance in the rail system.Some ASTRail Partners have already participated in S2R projects, while others have been specifically involved to cope with some vertical tasks. From a different point of view, the Consortium is well balanced with both research organizations and industrial stakeholders of the rail domain.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'User focused object oriented software engineering practice' to be submitted under Fourth Framework.

assistant: **Abstract**

The growing complexity of business and its impact on software engineering make it necessary to gather requirements more accurate and to transform them to software (business objects) in a traceable way. Otherwise projects easily run out of time and budget or fail to deliver the requested product.With UFOSEP (User Focused Object-Oriented Software Engineering Process) we are able to register/transfer user requests more efficiently. The customers should get higher quality products in a shorter period.Development is done iteratively to allow for the controlled reworking of parts of a system to remove mistakes or to make improvements based on user feedback as early as possible. This shorter, iterative process life cycle requires a reduction of the overhead to release software.THE EXPERIMENTA new use case driven and iterative SEP - will be experimentally introduced at AXIOMA. The important questions concerning the risks of integrating the new design with the existing implementation sub process as well as introducing a better support for the iterative process are answered. The method will be supported by an upper case tool and a configuration management tool. To achieve the objectives above the following activities are set:1. Rumbaughs OMT, Jacobsons OOSE, prototyping and ISO-9000 are merged to UFOSEP, a new user focused object-oriented method. Software engineers of the baseline project are trained.2. In a second step UFOSEP supported by an upper CASE tool (Select OMT or Cadre ObjectTeam) is used for analysis and design of the baseline project.3. The new design and the current implementation sub processes are integrated. The transformation of design deliverables into input for code generation by our internal lower CASE tool is partially automated to be able to estimate the bene
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Characterization of the role of netrin-1 in the regulation of the Epithelial-to-Mesenchymal Transition during tumor progression.', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Recent data coming from both basic research and clinical trials converge toward the importance of the epithelial/mesenchymal status of a tumor to respond to conventional chemotherapies and immune-checkpoint inhibitors. These observations set the Epithelial-to-Mesenchymal Transition (EMT) program at the centre of cancer biology. Besides its multiple roles in development and during adulthood, EMT is activated during tumor progression not only to allow metastatic dissemination of cancer cells, which is responsible for the vast majority of patients’ death, but also to provide cells with stem-like properties and resistance mechanisms to survive chemotherapy. It is now widely accepted that future therapies will have to target and/or block the EMT process and allow conventional therapies to efficiently kill the differentiated, epithelial cells to treat patients with advanced solid tumors.  NetriCan will analyse for the first time the implication of netrin-1 and its dependence receptor UNC5B in the regulation of EMT, either directly or via its cell death-related function. Moreover, the re-epithelialization effect of the anti-netrin-1 monoclonal antibody observed in tumors in vivo and in a preliminary cohort of patients shows that netrin-1/UNC5B may not only be involved in the direct regulation of maintenance of EMT but also serve as a survival mechanism for metastatic tumor cells. To achieve this, Netrican will first analyse how the upregulation of netrin-1 and UNC5B is regulated during EMT. It will then investigate the role of the netrin-1/UNC5B axis in the establishment and maintenance of the EMT program needed for cell dissemination and metastasis. Finally, this project will elucidate the therapeutic potential of the anti-netrin-1 strategy for both triggering primary tumor r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Development of a multifunctional system for complex aerostructures ASSembly, ASSisted by Neural Network', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

In today’s workplace, the increasing use of new technologies such as Artificial Neural NeIn today’s workplace, the increasing use of new technologies such as Artificial Neural Networks (ANN) in Artificial Intelligence (AI), Mixed and Augmented Reality (MR/AR) and Collaborative Robotic (Co-Robot) is helping to improve the productivity of many industries. Therefore, a future aircraft factory would be incomplete if essential technologies are not considered. It is, therefore, necessary to innovate the assembly and quality control processes of aerostructures taking advantage of the new support of these new technologies. This will help to achieve higher efficiency and quality in aircraft production and to reduce the risk of failures due to manual activities to zero. The main objective of the ASSASSINN project is to develop and validate a robust multifunctional assembly cell able to assist manual activities as the installation of typical fuselage systems and equipment, including cabling through the cabin structures or the application of sealant.This cell will guide the worker using Mixed and Augmented Reality during the assembly and inspection processes. The worker will be assisted by a Co-Robot while Artificial Intelligence algorithm based on Neural Networks will check the quality of the results.The solution proposed by ASSASSINN will take into consideration the driver factors indispensable for the industrialization: increased structural integration, reduced total costs and structural weight, enhanced multifunctional materials, reduced environmental impact and extended duration of aircraft life.The project counts with a strong consortium composed of 3 different partners with complementary profiles and large expertise: two research centers, CEIT and SUPSI, with a background an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Biological rhythms: Do they cointegrate?' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Many biological systems can be seen as networks of interconnected oscillating units. Unraveling how they interact, coordinate and influence each other in a random environment is essential for understanding systems such as the dynamic brain. The problem is that the current statistical methods are insufficient for solid data analysis. To solve this problem, I will elaborate the methodology of cointegration analysis, which has been applied mainly in econometrics, to provide a principled statistical framework for analyzing experimental data from neuronal systems. I will work on this project under the supervision of Professor Susanne Ditlevsen at the University of Copenhagen (UCPH).


**Keywords:** cointegration, biological oscillators, coupling, EEG data
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Innovation driven Initiative for the Development and Integration of Indian and European Research' (2007-2013) targeting Seventh Framework.

assistant: **Abstract**

INNO INDIGO will set up a more relevant STI approach in terms of social and technical innovation, a broader in terms of funding and a more focussed in terms of topics - to answer the needs of the European as well as Indian societies and markets and address the needs of the engines for innovation. These are SMEs and industries as well as existing clusters of excellence. Future joint programmes will be directed towards the interaction of academia and industry a critical interface for effective innovation. It is also very important to use the STI experience of regions successful funding clusters of excellence for joint calls. On a larger scale INNO INDIGO aims at contributing to ensure global competitiveness and to satisfy social needs through innovation.Another important task of INNO INDIGO will be to optimize the outreach of the project and facilitate the networking of funding organizations in Europe and India in order to discuss, prepare and implement joint calls on a regular basis. Therefore an open platform for funders will be implemented. A number of national funding agencies has been involved in the joint calls of the ongoing ERA-Net. This was important to gain experiences, approve and adjust tools and methods in existing strategies for the call management. Within the INNO INDIGO process of the future joint calls the strategies for an enhanced management structure will steadily analysed and optimized also in order to develop common governance principles. Further funding organizations in both Europe and India will be informed about the ongoing collaboration in order to raise their interest in a participation and therefore to enlarge the outreach of the project. In Europe this implies especially Member States as well as Associated Countries that do not have bilateral
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Privacy-aware Secure Monitoring' (PRISM) targeting Seventh Framework.

assistant: **Abstract**

Passive network monitoring is required for the operation and maintenance of communication networks as well as to detect frauds and attacks. Typically, raw packet-level traffic traces are collected using suitable traffic probe devices and fed to monitoring applications (IDSs, antivirus, etc..) for analysis, with potential risks for the legitimate privacy rights of the customers. This projects aims to show that it is technically possible to devise a privacy-preserving network monitoring system where carefully designed data protection mechanisms can coexist with suitably adapted monitoring applications.<br/>The proposed approach is based on a two-tier system. A first front-end tier of data protection mechanisms will be directly enforced at the traffic probe devices. The front-end cryptographic mechanisms will be controlled by a separate entity (privacy-preserving controller). The collected (and already protected) data will be delivered to a second back-end tier, which is implemented as a privacy-enforcing middleware and provides an additional level of data protection to enable privacy-preserving access and/or sharing of the acquired data to external parties. By interacting with the privacy-preserving controller, the back-end provides the capability of selectively removing data protection in specific cases (namely in the presence of attacks, abuses and in general when reaction is needed) and on the minimal amount of collected data necessary to enable such reactions.<br/>The system will exploit standard-based protocols for data exporting, in order to achieve interoperability. It will be designed from the beginning to comply with the privacy regulation set forth at EU and regional levels: the back-end will express privacy regulations into concrete rules in an ontology languag
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Mouse models to analyse the role of telomerase in cancer and aging', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

Chromosomal ends have protective structures named telomeres that distinguish them from broken chromosomes. Telomeres are composed of tandem G-rich DNA repeats bound to an array of proteins that are essential for telomere capping. The synthesis of telomeres by telomerase and their function are proposed to be biological determinants in the process of cancer and aging. Telomere dysfunction because of short telomeres or mutation of telomere-binding proteins can lead to chromosomal end-to-end fusions and loss of cell viability. I will test the relevance of telomeres and telomerase in tumour development and aging using mouse models deficient for proteins that are important for telomere function, such as telomerase (Tere knock-out mice) and telomeric binding proteins (Ku86 and DNA-PKcs knock-out mice). Further I will study transgenic mice overexpressing the catalytic subunit of telomerase (mTert) in adult tissues that normally lack telomerase to directly analyse the impact of telomerase upregulation for tumour growth and ageing. I will test whether telomerase cooperates with loss of p53 in tumorigenesis using telomerase transgenic p53 knockout mice. Additionally I will evaluate the role of telomeres and telomerase in tumourigenesis by analysing double mutant mice lacking telomerase, with an activatingCdk4 R24C mutation, present in human hereditary melanoma. The analysis of these different mouse models should help to understand the function of telomerase intelomere maintenance, cancerogenesis and age-associated diseases.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Development and Commercialisation of Transbronchial Lung Ablation to Treat Lung Cancer' (TABLA).

assistant: **Concept**

Lung cancer is the most common cause of cancer deaths in the EU and worldwide with more than 0.4M people diagnosedeach year. It has a dismal 5 year survival rate of just 18% and worldwide someone dies of lung cancer every 30 seconds.The impact of the disease on public health is substantial with > 6M hospital admissions in Europe each year (>€18 billion ineconomic costs). Surgery has been shown to provide a curative solution, but only 20-30% of patients can undergo surgerydue to co-morbidities.Endowave have developed a pioneering device, designed to destroy the targeted tumour in a single, minimally invasiveintervention. The patented technology uses a flexible catheter system, that can be navigated through the patient’s airway todeliver targeted microwave heating to the tumour. This will enable physicians provide a curative treatment that can bedelivered in an outpatient setting, improving patient outcomes and reducing costs to healthcare system.The global market opportunity for lung cancer exceeds €3.6 billion. Endowave has formed a consortium of leadingcompanies that seeks to commercial Endowave’s technology and capture this market opportunity. The proposal is seekingfunding to complete the final development of the microwave system, carry out clinical studies achieve regulatory approval.This will enable Endowave to enter the market, where we forecast revenues of €60 million by Year 5 based on conservativemarket penetration forecasts. This project will drive job generation in Endowave and consortium partners as sales volumesincrease.


**Keywords:** Lung cancer, thermal ablation, minimally invasive, microwave, transbronchial
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Non chemical postharvesting treatments and optimization of a green" protocol for long storage and long distances transport, incluiding overseas, for citrus."' under Fifth Framework.

assistant: **Concept**

Most of trade, in the European market, is performed through long distances. For fresh fruits, citrus in concrete, it leads to long storage and long distance transport. Long storage and long distance transport replies the use of appropriate technologies as refrigeration and the use of chemical fungicides to avoid decay. On the other hand, customer is day to day more concerned about environmental risks and particularly about chemical pollution in food, as pesticides traces, etc. Nowadays the amount of commercialised citrus under green" philosophy is irrelevant, due to decay. As consequence of this, most of citrus traded under long distances transport are treated with synthetic fungicides. When aggressive marketing efforts have been done in supermarkets the percentage of decay it has become unproved table. However, if we may have natural fungicides, no chemicals, with enough performance it is practically sure that market would change 180°. We propose a strategy to do it."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'SUBSEA WELL TESTING SYSTEM FOR UNDERWATER MULTIPHASE PRODUCTION [PHASE 1]'.

assistant: **Concept**

The project is aimed at the design, fabrication and testing of an innovative subsea well testing system based on the utilisation of a two-phase separator, to provide for each well the production data needed for the reservoir management in those scenarios where conventional surface testing is not technically available or economically feasible. Particular reference is made to the subsea multiphase production used for the exploitation of offshore marginal fields.The main results of the project are relevant to the fabrication of an experimental prototype of subsea multiphase well testing system that has been tested with different multiphase flows simulating the operating conditions in order to prove its performances.The project allowed to demonstrate the feasibility of the concept and the high level of operability by means of tests on the system prototype (which was prepared for this purpose in a verson not adaptated for subsea use on account of the limitation of the project itself).The proposed underwater well testing system is based on the integration of proven technology, that has to be finalized to the specific innovative application, with the technical innovations, mainly achieved in the instrumentation field, in order to provide a system that will be used in the near future.In particular the System is mainly based on:- two-phase test separator, to facilitate the multiphase flow metering operations- innovative" instrumentation, able to perform with oil/water mixture and with entrained gas and wet gas stream (entrained liquid in the gas stream)- conventional instrumentation, modified for the specific application, for the monitoring of the gas phase mainly.The application of a gas/liquid separator for the underwater well testing requires also the utilization of both "con