RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Advanced profiling technologies for light alloys and reinforced pla stics with large dimensions and small-batch ordersizes' under Fourth Framework.

assistant: **Concept**

The primary objective of the proposed research project is to provide European SMEs with know how to enable safe and economically productive contour milling and thermal laser cutting processes on lighthweight materials in aircraft and shipbuilding industry. The range of the envisaged materials contains difficult to cut multi layer light metal structures like Alhoneycomb sheets, coated Al sheets and Al sandwich structures as well as reinforced plastics like glass reinforced plastics (GRP), carbon reinforced plastics (CRP) sheets and Aramid reinforced plastics. To increase the quality and performance of the cutting process extensive investigations concerning adapted process parameters and specially adapted milling tools with special wear resistant coatings and geometries will be carried out. The milling tools will be developed and designed according to the milling process requirements. Additionally, workpiece clamping devices, suitable for clamping multi layer structures within the cutting processes will be investigated and optimised for industrial application. The secondary objective is to develop strategies for the ecologically beneficial layout of the relevant cutting processes by use of environmental friendly ester based coolants, the reduction or avoidance of coolant and cleaning media by minimum quantity lubrication and dry machining. The reduction of aerosol, dust and toxic fume emission by careful selection of process parameters and special exhaust systems are additional keys for solutions to improve working conditions. The third objective of the project is to optimise the production and system performance via co operative partnership between companies and research technologies institutions by set up of a cutting parameter data base for the selected materials to su
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'SELF OPTIMISING MEASURING MACHINE TOOLS' (SOMMACT), addressing dissemination and exploitation.

assistant: **Impact**

SOMMACT develops and validates an innovative production hardware and control system founded on understanding, evaluating and controlling production system performances. This approach is based on detection (in-process traceable measurement embedded capabilities) and compensation (adaptive control and self-learning capabilities) of geometrical effects of varying external and internal quantities, such as temperature gradients and workpiece mass. Knowledge accumulated by SOMMACT approach is available for the higher level of a production system management, supporting self-optimisation and decision making, including the implementation of predictive/virtual metrology methods. The SOMMACT vision is based on three pillars: 1. A new metrological concept to enhance the measuring capability of machine tools, to monitor the machine geometrical deformation reliably and to inspect machined part characteristics traceably; 2. Enhanced sensor systems, measuring the 6 degrees of freedom of each machine component, and a control system integrating machine and workpiece data with environmental and load conditions, and adapting machining accordingly; 3. A self-learning model of the system performance, accumulating knowledge on the machine performance, based on calibration and real-time measurement data, and on their relationship with workpiece characteristics and the environment. The advantages are an improved product quality at competitive costs, and a prediction capability of the system performances based on a increasingly reliable model. The SOMMACT units can either stand alone, or be integrated into production systems as basic building blocks, enabling flexibility and easy reconfiguration under contingent conditions. Furthermore, the MT measuring capabilities are enhanced to the point tha
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Cancer: Activating Technology for Connected Health' (CATCH).

assistant: **Concept**

Advances in cancer diagnosis and treatment have been groundbreaking, and we are now considering some cancers as chronic disease rather than fatal illness. This moves the point of focus in the fight against cancer from sustaining life towards maximizing functional capacity and quality of life (QOL). A critical element in this shift has been the rise of active rehabilitation in the management of cancer. In the past 10-15 years we have seen the emergence of significant evidence for the clinical effectiveness of active rehabilitation in cancer care, both in maximizing functional capacity and QOL, and preventing secondary recurrence. However, many barriers to implementation of active rehabilitation in cancer care exist due to its profound physical and psychological implications. Technology advances such as gamification based on biofeedback, and neuromuscular electrical stimulation, can help address some of these barriers but much must be done before we can effectively marry the technological capability to the unmet clinical need. In particular we need to understand specific challenges and patient journeys associated with cancer care and how we can help patients to leverage psychological tools to better engage in their own care. We then need to optimize technological tools to meet patients’ rehabilitation needs, and finally, to understand how to bring resultant solutions to market where they can have maximal impact on quality of care. This can only be done by a multidisciplinary programme of research involving close collaboration between researchers in academic, clinical and industry settings. CATCH is a deep collaboration across academic, business and clinical sectors. Students will benefit from intersectoral secondments, interdisciplinary communication skills, public engage
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Environmental control of carotenoid biosynthesis: a novel strategy to improve photosynthetic capacity' (SMARTPLANT).

assistant: **Innovation**

Security of our future food supply will depend on our improved understanding of how plants regulate photosynthesis in response to a changing environment. Carotenoids are important for photosynthetic efficiency because they expand the range of wavelengths for photosynthesis and protect the photosystems against photo-oxidative damage. As environmental light and temperature cues are major regulators of carotenoids, increased knowledge of these signaling pathways will assist future crop improvement programs. This project aims to combine modeling with experimentation to determine the molecular mechanisms through which light and temperature modulate carotenogenesis, providing novel avenues for efforts to improve photosynthesis in the face of environmental change. A major driving force for carotenoid production is the transcriptional control of Phytoene synthase (PSY). The phytochrome photoreceptors promote PSY expression, while the PHYTOCHROME INTERACTING FACTORS (PIFs) act as transcriptional repressors. This antagonistic module provides a simple but robust system to modulate carotenoid biosynthesis. The Giberellin regulated DELLA proteins also participate in the light control of carotenogenesis by impairing PIF1 capacity to bind to the PSY promoter. However, in the light, not only de-repressing effects, but active induction of PSY takes place, hinting at the existence of positive regulators of the pathway. Preliminary evidence points at LONG HYPOCOTYL 5 (HY5) for this role. Many phytochrome dependent responses are strongly influenced by temperature, suggesting a convergence of signaling at the molecular level. Because PIFs, DELLAs and HY5 are temperature responsive, they could be integration nodes for environmental control of carotenogenesis. We aim to characterize they key
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Generalised Integrality and Applications to Number Theory' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

In this proposal semi-integral points refer to notions of rational points on algebraic varieties that satisfy an integrality condition with respect to a weighted boundary divisor. They were first introduced by Campana and by Darmon. Campana points have recently risen to the attention of the number theory community thanks to a Manin type conjecture in the recent work of Pieropan, Smeets, Tanimoto and Várilly-Alvarado. Semi-integral points provide both an intermediate notion and a generalisation of the notions of rational and integral points, thereby unifying the two theories. This proposal concerns the existence of semi-integral points and the density of orbifold pairs in general families having semi-integral points. The aims of this proposal are to determine good upper bounds for the density of orbifold pairs in a general family that have semi-integral points (WP1) and to compute obstructions to the existence of semi-integral points (and hence to integral points) in key examples corresponding to long-lasting questions in number theory (WP2).The approach will combine a variety of techniques from analytic number theory, algebraic geometry and arithmetic statistics. For (WP1), the experienced researcher and the supervisor will develop a criterion to detect local semi-integral points together with a sieve method to estimate the number of everywhere locally soluble varieties in the family. For (WP2), the research team will develop a Brauer-Manin obstruction theory for semi-integral points to compute failures of the integral Hasse principle in fundamental examples and handle classical Diophantine problems such as the existence of integral points on diagonal cubic surfaces and the non-existence of consecutive powerful numbers.


**Keywords:** Semi-integral points, Campana poin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Advanced Multi-modal Intelligence for Remote Assistance', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

The business goal of AMIRA is to significantly improve the accessibility and resources available to support urgent and critical diagnostics and decisions that must be taken by mobile workers, operating individually or in multi-discipline collaborations, at their point of intervention in an event. The technical goal of AMIRA is to develop a set of reusable components using search, reasoning, speech dialogue technology and collaborative working techniques that can be used to create applications for use by mobile workers operating in safety or business critical situations in the field. The prototype application developed in AMIRA will be a wireless, easy to use, intelligent, real-time diagnostic and decision support system for mobile workers using multi-modal devices such as wireless earphone/microphone, PDA or UMTS phone. The focus of the work will be on providing multi-modal assistance at the point of intervention in time-critical, safety/business critical incidents. AMIRA will be demonstrated as providing a tool for the mobile worker in both fairly simple and highly complex scenarios. Building on the work and results of current and previous RTD projects, AMIRA will widen the applicability of advanced search and reasoning technologies to make it possible to access these through a speech dialogue interface. By coupling speech dialogue technologies with search and reasoning technologies, structural case based reasoning (CBR) will drive the intelligence behind the dialogue, generating the questions to be automatically answered. AMIRA will provide semantically based and context aware systems that can acquire, organise, share and reuse knowledge in structured and unstructured format. It will extend CBR with the ability to process trends in data, in order to be able to identif
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'TWAICE predictive analytics and digital twin ecosystem to optimise and automate batteries second life and re-use' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Our solution solves the major cost and safety problems posed by batteries. TWAICEs predictive battery analytics platform can be implemented at all stages of the battery value chain, optimizing processes such as development, operation and re-use (second life). There is a substantial lack of transparency in Li-ion batteries, a problem which can lead to overly high development and operation costs and pose safety risks. Our software addresses this problem by empowering customers to better understand their batteries. They can obtain precise diagnoses and prognoses on battery health and remaining lifetimes, using this information to inform their strategic operational decisions. Underpinned by digital twin technology, we combine battery knowledge with artificial intelligence and machine learning to solve the specific customer needs mainly in the energy and mobility sector. Wherever it is applied, our solution will make significant contributions to reducing CO2 and ensuring a greener future.


**Keywords:** Machine learning and statistical data processing,Energy,Emission free mobility,Battery technology,Battery efficiency,Energy storage
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Synthetic Biology for Architecture'.

assistant: **Concept**

Synbio4Arch intends to leverage the foreground generated in the FET project LIAR to develop a synthetic biology toolkit for architecture. The envisaged technology will allow engineers and architects to leverage microbes to embed distributed biomanufacturing, on-site domestic waste treatment and CO2 capturing into buildings. The innovation will consist in a cloud-based application that allows architects and engineers to select microbial strains engineered with pre-made and validated synthetic metabolic pathways relevant for household wastewater management such as organic compound oxidation and inorganic phosphate recycling. The innovation will allow practitioners in the construction field (such as engineers and architects) with little expertise in molecular biology to access the power of synthetic biology. Toward this aim, this launchpad proposal aims to assess regulatory barrier and develop a commercialization plan to exploit Explora’s proprietary doulix platform developed within the framework of the LIAR project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Nanocrystals for electronic applications' to be submitted under Fifth Framework.

assistant: **Abstract**

This proposal targets the fabrication of new electronic memory devices making use of nanocrystals instead of poly-Si as charge storage elements. Such memory devices could more easily be miniaturized allowing an increase of the information storage capacity and a decrease of power consumption. The proposed processes to form nanocrystals are based on ion beam synthesis or deposition techniques. The main technical and scientific objective of the project is the Materials Science investigation of the Self-Assembly process for the formation of well defined patterns of 3-5 nm nanocrystals and the engineering of reliable memory devices based on such schemes. The proposed processes can result in the formation of 2-dimensional patterns of nanocrystals. Such structures will be optimized through a systematic feedback from characterization techniques (structural, chemical and electrical) and predictive simulations in order to find best process windows for the fabrication of demonstrator devices.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Modelling Neuron-Glia Networks into a drug discovery platform for Pain Efficacious Treatments - Sofia ref.: 116072' (NGN-PET).

assistant: **Concept**

Chronic Neuropathic Pain is frequently associated with peripheral nerve injury or disease. Peripheral injury activates both neuronal and glial components of the peripheral and central cellular circuitry. While it is widely known that the subsequently altered interactions between neurons and glial cells contribute to pain development and to its chronification, the underlying mechanisms are poorly understood. Developing mechanism-based therapies targeting neuron-glial interactions to treat chronic pain will be crucial for improving the quality of life of many patients. Hence the development of novel therapeutic solutions represents a major challenge that demands a multi-disciplinary approach to decipher and understand pathological mechanisms and to translate them into predictive tools for drug development. The NGN-PET consortium addresses this challenge by forming a highly interdisciplinary team that builds upon expertise in areas of academic research on painmechanisms, industrial knowhow on human stem cell-based tool development, HTS technologies and drug discovery. To achieve its goal we will develop preclinical model systems and assays which recapitulate the human in vivo situation and which can be interrogated for the identification, validation of molecular targets and the development new treatments. A focus of the project will be chemotherapy induced NP and the interplay between nociceptors, microglia and Schwann cells. NGN-PET will carefully characterize rodent in vivo and in vitro models to identify these mechanisms, and will develop rat and human iPSCs based in vitro systems of neuron-glial co-cultures that can be interrogated for targets and used for compound identification and validation. NGN-PET will thus pose the basis for the translation of these model system
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Characterization of Novel Phosphatases/Sulfatases Mutants Obtained by Directed Evolution', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

The objective of this research is to gain deeper insight into how enzymes bring about catalysis of two central bioreactions, phosphate and sulphate transfer. We will use directed evolution approaches to find molecular solutions to travel the evolutionary distance between these two mechanistically related reactions. The choice of reactions is triggered by the observation of catalytic promiscuity, i.e. an enzyme activity in addition to the one it is evolved for and a possible starting point for natural evolution. In this way we attempt to mimic the way nature may have evolved new function. Kinetic and mechanistic experiments (in particular transient, pre-steady state kinetics) will enable us to trace the structural and quantitative mechanistic basis for the acquisition of a new catalytic activity.