RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Optical dissection of circuits underlying fast cholinergic signalling during cognitive behaviour' under Seventh Framework.

assistant: **Concept**

Our ability to think, to memorize and focus our thoughts depends on acetylcholine signaling in the brain. The loss of cholinergic signalling in for instance Alzheimer’s disease strongly compromises these cognitive abilities. The traditional view on the role of cholinergic input to the neocortex is that slowly changing levels of extracellular acetylcholine (ACh) mediate different arousal states. This view has been challenged by recent studies demonstrating that rapid phasic changes in ACh levels at the scale of seconds are correlated with focus of attention, suggesting that these signals may mediate defined cognitive operations. Despite a wealth of anatomical data on the organization of the cholinergic system, very little understanding exists on its functional organization. How the relatively sparse input of cholinergic transmission in the prefrontal cortex elicits such a profound and specific control over attention is unknown. The main objective of this proposal is to develop a causal understanding of how cellular mechanisms of fast acetylcholine signalling are orchestrated during cognitive behaviour.In a series of studies, I have identified several synaptic and cellular mechanisms by which the cholinergic system can alter neuronal circuitry function, both in cortical and subcortical areas. I have used a combination of behavioral, physiological and genetic methods in which I manipulated cholinergic receptor functionality in prefrontal cortex in a subunit specific manner and found that ACh receptors in the prefrontal cortex control attention performance. Recent advances in optogenetic and electrochemical methods now allow to rapidly manipulate and measure acetylcholine levels in freely moving, behaving animals. Using these techniques, I aim to uncover which cholinergic n
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Innovation Relay Centre for Northern England and France Nord Manche' (2002-2006), addressing dissemination and exploitation.

assistant: **Impact**

The main aim of this proposal is to contribute to the objectives of the European Research Area and the Research and Innovation Programme by assisting companies, universities and research institutes with the exploitation of research results, transnational technology transfer and to maximise the benefits of Community research. The services proposed to meet this aim will be split into four main workpackages: 1) Services to IRC Clients - this includes transnational technology transfer (TTT), increasing the c apacity of firms to participate in TTT and the dissemination of the results of Community R&D 2) Services to the IRC network - participation in transnational thematic groups, brokerage / partnering events, submission off high quality technology offers and requests to the network and development and exchange of good practice across the network. 3) Internal IRC matters - to ensure effective management and coordination of the IRC. 4) Anglo-French component - to ensure the added-value of functioning as a transnational IRC is disseminated to the wider network while maintaining the unique relationship built up over the past three years between the UK and French partners. These activities will result in the following hard results: 400 technology offers and requests submitted to the network or processed locally, 2800 expressions of interest leading to negotiations, 72 transnational technology transfer agreements Alongside these results 1100 number of companies will be provided with hands-on assistance to participate in transnational technology transfer and significant effort will be given to the increasing the effectiveness of the network as a whole.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'The role of mature male parr for brown Trout populations'.

assistant: **Concept**

I aim in the proposed project to study how mature male parr effect brown trout populations. This will be done in two steps, where the first step investigates how mature parr are genetically related and if they aggregate into groups. This is done both in the spring (May- June) and just prior to spawning.Aggregations of mature parr into groups can if the intra-group relatedness is higher than the inter- group relatedness facilitate kin- selection in form of reduced aggressiveness among group members and less fierce competition. It is also interesting to see if groups are found throughout the summer or if they appear prior to spawning when competition for matings should be fierce.The second step would be to study what role mature male parr have at spawning both for polyandry and for maintaining high genetic variation within the populations. These two steps would be studied by sampling a number streams with varying proportions of mature parr. As well as sampling fertilised eggs from a number of redds.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Sustainable biomass district heating plant tamsweg' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

The project concentrates on several main objectives. The first aim is to increase the energy output of biomass district heating plants significantly. This is achieved by improving the efficiency of combustion of the energy recovery from the flue gas condensation unit and by reducing the electricity consumption of the whole process with well-designed pumps and fans. An optimized pipe network design will reduce heat losses and will in addition decrease the investment costs. Moreover, a fuel drying system is intended. The second aim of this project is to increase the sustainability of such systems. To achieve this aim a NOx reduction by primary methods is foreseen. Furthermore, it is not only necessary to close the CO{2}-cycle, which is possible by a sustainable wood culture, but also to close the elementary cycles of nature by recycling the wood ash produced. A new combustion technology will enable the separation of ash fractions with a low amount of heavy metals and ash fractions enriched with heavy metals. In this way 90 to 95 per cent of the ash produced can be recycled in forests in an ecological manner.The combustion plant will supply district heat to one of the coldest places of Austria, the town of Tamsweg. Both wood chips from local farmers and bark, sawdust and shavings from sawmills of the region will be used as fuels. The plant itself consists of two combustion units (moving grate incinerators) with boiler capacities of 5 and 3 MWth and a flue gas condensation unit. The network of pipes will be designed for a total capacity of 16 MWth.The innovative technologies are:- Biomass drying system: by drying the fuel with preheated air from the third stage of the condensation unit the energy output of the boiler increases due to the fuel's lower water content.- NOx red
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Functional Imaging and Robotics for Sensorimotor Transformation' (FIRST) targeting Seventh Framework.

assistant: **Abstract**

This proposed research addresses the question of how the brain transforms somatosensory information from the hand into motor commands to control the hand during tasks such as object manipulation and dexterous finger movements. Understanding the sensorimotor transformations performed by the brain to control upper limb movement is fundamental for a variety of fields, including motor development, athletic and artistic performance, sensorimotor rehabilitation, assistive technology and humanoid robotics. This project will investigate and model the computational processes underlying the sensorimotor transformations taking place in the brain during dexterous movements of the hand in neurologically normal individuals and individuals with impaired hand function following a stroke. This will be achieved by creating a set of novel haptic tasks implemented on state-of-the-art high fidelity haptic devices and quantifying the changes in performance and brain activity that occur as the tasks are learned. The changes in functional connectivity within brain networks as the tasks are learned will be used to determine how sensorimotor transformations are carried out in the brain. The performance measures and the way in which haptic features such as texture, compliance and shape are related to changes in motion and force during learning of the haptic tasks will be used to develop a computational model of how somatosensory information is transformed into commands to muscles that control the hand. Differences in changes in functional connectivity in brain networks between neurologically normal individual and post-stroke subjects during learning of haptic tasks will be used to advance our understanding of changes to the sensorimotor network of the brain following stroke. The computational mod
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Compact REtrofit Advanced Thermal Energy storage' in the context of a Horizon 2020 call.

assistant: **Objectives**

The CREATE project aims to tackle the thermal energy storage challenge for the built environment by developing a compact heat storage. This heat battery allows for better use of available renewables in two ways: 1) bridging the gap between supply and demand of renewables and 2) increasing the efficiency in the energy grid by converting electricity peaks into stored heat to be used later, increasing the energy grid flexibility and giving options for tradability and economic benefits. The main aim of CREATE is to develop and demonstrate a heat battery, ie an advanced thermal storage system based on Thermo-Chemical Materials, that enables economically affordable, compact and loss-free storage of heat in existing buildings.The CREATE concept is to develop stabilized storage materials with high storage density, improved stability and low price, and package them in optimized heat exchangers, using optimized storage modules. Full scale demonstration will be done in a real building, with regulatory/normative, economic and market boundaries taken into account. To ensure successful exploitation, the full knowledge, value, and supply chain are mobilized in the present consortium. It will be the game changer in the transformation of our existing building stock towards near-zero energy buildings. WP1 Management,WP2 Cost Analysis and planning for future commercial products cost,WP3 System definition,design and simulation,WP4 Thermal storage materials optimization (key breakthroughs),WP5 Critical storage components and technology development (key breakthroughs),WP6 Thermal storage reactor design, implementation and test,WP7 System integration, experiments and optimization,WP8 Building integration and full scale demonstration,WP9 Dissemination and exploitation of results. CREATE will c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Physics-informed nEuRal networks for SEVERe wEather event prediction' (PERSEVERE).

assistant: **Innovation**

The novel development of Physics-Informed Neural Networks (PINNs), which incorporate the constraints given by physics laws into the training process, as excellent means of computing fluidic fields and their characteristics such as velocity and pressure has open the gates to numerous applications. One of them is the data enhancement of experiments, since PINNs can reconstruct by means of applying the Navier-Stokes equations as loss function the full fluid domain in areas where experiments are limited by technology. On the other hand, the development of Generative Adversarial Networks (GANs) as robust networks with excellent precision but excessive computational costs leaves the door open to further investigate new applications where PINNs and GANs can be combined to amplify their strengths and reduce their weak points. One of those applications regards the forecast of severe weather conditions, where PINNs are useful to compute the fluidic behavior of storms approaching a certain location, whereas GANs can incorporate many additional parameters, such as wind speed, humidity, temperature and electric content, which may be essential to determine if in the following 48h a certain location is going to suffer from severe weather conditions. The estimation and forecast of storms is essential to the air transport industry, since the losses incurred due to delays and deviations of air traffic caused by the presence of storms have been reported to be over $38.5 billion in USA. The development of a computational architecture which is able to determine if severe weather events are going to take place within the next 48h is therefore of crucial importance. There exists no model nor application in which the combined strengths of PINNs and GANs have been put into practice, one to rapi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Domestic forests and wood culture in the continental Euro-Atlantic region (1300 – 1600 CE): explaining change and redressing biased perspectives' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Woodlands in the continental Euro-Atlantic region became heavily exploited from the Late Middle Ages onwards. The timber demand of growing cities and fleets promoted changes in oak (Quercus sp.) forestry practices and long-distance timber trade, aiming to provide a fast and sustainable turnover of construction wood. Progressively, changes in timber-framed buildings and ship designs took place during the 15th and 16th centuries, concurrently with shifts in woodworking techniques. Whether and how these changes and shifts in wood culture were interrelated, is still a debated question. Dendrochronological datasets biased towards wood from old trees, limited archaeological records, and fragmented historiography have hampered thus far finding the answer.WoodCulture aims to explain changes on and redress biased perspectives about domestic forests, timber supply, building activity patterns and technological innovations in the continental Euro-Atlantic region during the Late Middle Ages and the Renaissance (c.1300-1600 CE). I will retrieve the currently missing wood archive of young and fast-growing oaks from managed forests, along with its associated historical, technological and environmental context, combining isotope dendrochronology, archaeology and history with 3D scanning, AI and GIS.This ground-breaking interdisciplinary approach will provide a novel, empirically-founded narrative about changes in woodlands and interdependencies between timber products, construction designs and technological innovations in the continental Euro-Atlantic region. Moreover, it will reveal whether domestic forests became sustainable suppliers of construction timber at local/regional scales, putting the magnitude of timber trade into perspective. The developed set of tools will revolutionise f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Metabolism of a cell pictured by single-cell approach' to be submitted under Horizon 2020.

assistant: **Abstract**

Every cell is unique. Metabolites define the composition of each cell and play key roles in essential intracellular processes of energy production and uptake, signaling, regulation, and cell death. Obtaining metabolite signatures of individual cells and linking them to cellular phenotypes is of paramount importance for a holistic understanding of these processes. This requires high-throughput single-cell metabolomics that is not generally attainable due to the limited sensitivity, low throughput, and disruptiveness of state-of-the-art metabolomics methods. I propose to develop a spatial single-cell metabolomics approach for human cell culture systems. The approach will be based on using metabolite imaging mass spectrometry and will provide metabolite profiles of individual cells and metabolite signatures of single-cell phenotypes identified by light microscopy. With this approach developed, I will investigate the link between the intracellular metabolism and single-cell phenotype and focus on the following questions: How is the intracellular metabolism linked to cellular heterogeneity? How high is the variation of essential metabolites in a cell population? How do the energy metabolism and lipids biosynthesis change through the cell cycle and infection stages? What is the metabolic response to inflammatory signals? I will scale up the analysis to discover novel cell phenotypes both in the cell culture systems and in big metabolite imaging mass spectrometry data from various biological systems provided to us by our collaborators and the community, and representing billions of cells.My project will enable spatial single-cell metabolomics on a large scale and will provide yet lacking capacity for investigating and visualizing the intracellular metabolism on a single-cell l
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'GLOBAL_AT_VENICE - Research and Training for Global Challenges Cofund Fellowship Programme' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The Global at Venice - Research and Training for Global Challenges is a new 60-month Cofund Fellowship Programme implemented by Ca Foscari University of Venice (UNIVE) that aims at exploiting the full potential of UNIVEs and its strategic partners to offer to 15 Fellows a truly international, interdisciplinary and inter-sectoral training.The G@V programme will strengthen the Fellows curricula, providing Europe and the world with a pool of researchers capable of bridging the gaps between academic and applied research, and between research to market. In 2014 UNIVE launched an ambitious Strategic Plan aimed to boost its position to become a leading research-intensive university. Huge investments together with a radical mind-shift led to the following initiatives:2014: BRAIN GRAIN programme 2015: CAREERS+ programme 2016: HRS4R - Human Resources Strategy for Researchers label2016: LAB programmeRESULTS 2014-2019: UNIVE is now a top Host Institution with more than 60 Marie Skodowska Curie Individual Fellowship awarded, 10 ERC grantees, 97 H2020 projects worth over 27M so far.In 2019 UNIVE set up 6 Research for Global Challenges Institutes to promote an interdisciplinary, challenge based and mission oriented approach to research: 1  Research Institute for Complexity 2  Research Institute for Digital and Cultural Heritage3  Research Institute for Social Innovation4  Research Institute for Cross Cultural Relations5  Research Institute for Green and Blue Growth 6  Research Institute for Innovation ManagementThe key features of the G@V - Research and Training for Global Challenges Cofund Fellowship Programme  are:- 15 Fellowships lasting 24 months;- interdisciplinary research within the Research for Global Challenges Institutes;- excellent research training paths with top superviso