RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Elucidation of the molecular basis of the inhibition of microtubule dynamics'.

assistant: **Innovation**

An atomic level explanation of the molecular basis of the action of anticancer agents inhibiting microtubule functions has been a long sought and yet partially unsolved goal in cancer research. In cells tubulin exists in a state of dynamic equilibrium between a heterodimeric form and a polymeric form, generally refereed to as microtubules. The intrinsic dynamic instability of microtubules is essential for their function, particularly mitosis. Compounds altering this dynamic exchange interfere with cell proliferation and are promising candidates for cancer chemotherapy. Several classes of natural products were recently observed to induce mitotic arrest by interfering with either the disassembly or assembly of the microtubule network, ultimately leading to apoptotic cell death.Over the past decade continuous efforts were made on the elucidation of the molecular bases of the anticancer activity of tubulin-binding ligands; however, they have not provided a coherent picture. In the proposed project information on the binding conformation of microtubule-targeted depolymerising agents will be gained by novel solution NMR spectroscopic methodologies in combination with synthetic organic, computational and microscopic techniques. The localization of the pharmacon binding pockets of tubulin as well as the relative binding orientation of the ligands in their respective pockets will be assessed by a new technique (INPHARMA) recently developed by the host department. Hence, our study will, for the first time, allow systematic mapping of the binding pockets of tubulin depolymerising agents and provide description of tubulin-ligand interactions at molecular level.Results are expected to have an impact on the development of novel anti-cancer drugs of improved activity. In addition, the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'A multi-century history and future of fire occurrence in the Mediterranean Basin and its climatic and atmospheric drivers (REGIME)'.

assistant: **Objectives**

Wildfires in the Mediterranean region pose a critical impact on human lives, ecosystems, and socio-economic stability. Understanding the multidimensional nature of wildfires is crucial for assessing future ecosystem dynamics and fire management strategies. The underlying coupled mechanisms of the interaction between fire, climate components and atmospheric drivers that affect regional fire regime characteristics (fire frequency, seasonality, severity, extent etc.) are still poorly understood. Therefore, there is an urgent need for interdisciplinary approaches to address climatic and atmospheric drivers of fire occurrence, especially, in fire-prone areas with diverse regional climate conditions such as the pyrogenic forest ecosystems of the Mediterranean Basin. The main goal of REGIME is to disentangle the complex relationship between fire occurrences, and the climatic and atmospheric drivers in the Mediterranean Basin in the past and ultimately model the future probability of fire occurrence.  To do so, a unique network in terms of spatiotemporal resolution of fire history of the Basin will be created combining documentary records and tree-ring-based fire reconstructions (WP1). The major modes of large-scale climatic drivers, atmospheric circulation patterns, and teleconnections that modulate fire occurrence will be analysed to understand the complex link to fire occurrence (WP2). Lastly, the potential future changes in fire occurrence over the 21st century will be evaluated to understand the driving factors and the potential consequences (WP3). REGIME's multidisciplinary nature is novel and unique which involves a combination of well-developed dendrochronology, atmospheric sciences, and fire ecology. Comprehensively studying climate-fire interactions, climate teleconne
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Measurement of Ozone by airbus in-service Aircraft' to be submitted under Fourth Framework.

assistant: **Abstract**

The MOZAIC II project corresponds to an extension of MOZAIC I programme for a two year new-phase with three main goals: - Continuation of MOZAIC I project (5 aircraft, O3 and H2O measurements, constitution of data bank). - Feasibility study of new airborne devices: NOy (chemiluminescence), CO (resonance fluorescence) and light compact computer (central unit). - Interpretation of MOZAIC data (MOZAIC I & II) to gain better understanding of atmospheric chemistry and dynamics.1) In-flight measurements:  The continuation of MOZAIC flights is required to increase the number and the representativity of  measurements. The measurements and acquisition of ozone, water vapour and aircraft parameters will be  continued on the 5 aircrafts already in service. Data quality will be maintained by continuing calibrations and  a careful calculation & validation of final data. The MOZAIC data bank, including relevant meteorological and  satellite data, will be established for the whole period (July 1994 - December 1998).  2) New developments:  The study of automatic airborne devices (feasibility of concept, laboratory and in-flight tests) for measuring NOy  (representative of active nitrogen compounds driving the atmospheric chemistry: NO + NO2 + NO3 + N2O5  + HNO2 + HNO3 + HO2NO2 + PAN + RNO2) and CO (both an ozone precursor and a tracer of pollution  originating from ground level) will be realised, in order to explore and to solve the complex problems raised  by the adaptation of existing technologies (chemiluminescence, resonance fluorescence) to the much more critical  requirements for an automatic and prolonged functionment abroad commercial aircraft.  3) Interpretation:  From the whole set of MOZAIC I & II data, quasi global climatologies of ozone, water vapour, relevant aircraft  pa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Green roofs that clean SME industrial gas containing low and variable concentrations of Volatile Organic Compounds' under Seventh Framework.

assistant: **Concept**

Cost-effectiveness for controlling emissions of Volatile Organic Compounds (VOC) in industrial waste gas depend on the characteristics of the gas emitted. SMEs affected by VOC emission Directive 99/13/EC (wood, printing, surface cleaning, dry cleaning, leather, vehicle refinishing) generate low and variable concentrations of several different VOCs in small volumes of waste air. This profile of VOC emissions will be the focus of the new Industrial Emission Directive 2010/75/EU, but it shows the most techno-economic problems for VOC control. GRABGAS will use rhizodegradation to treat small volumes of industrial waste air (1000 m3/h) with low and variable concentrations (30-300 mgC/m3) of several different VOCs with a removal efficiency of >93% to comply with directive emission limit values (20mgC/m3). Rhizodegradation uses plant roots, microorganisms and soil to biologically degrade VOC into CO2 and H2O. It can simultaneously degrade several VOC in very low concentrations or even when they are temporarily absent. GRABGAS will adapt to changing concentration of different pollutants, as well as to weekend and short holiday interruptions without losing removal efficiency. To make VOC mixtures more biodegradable, a solar photocatalytic pre-treatment using doped-TiO2 will be applied before rhizodegradation. To support plant growth and solar photocatalysis with sunlight, GRABGAS will be installed on industries’ roofs, following European green roof standards. Optimal air flow through the rhizofilter will be achieved by a substrate allowing root growth, high active surface for bacterial growth, permeability for air and VOC storage capacity. It will keep the internal temperature and moisture within constant ranges by appropriate sealing, insulation and drainage. Total economic ben
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'High pressure long length hose' under Fourth Framework.

assistant: **Concept**

The company supply products to the Offshore Oil and Gas Industry. The main product supplied is a rubber flexible high pressure hose. A number of areas within this market could benefit from further material and production developments. Within the area the total range of products supplied varies from Rubber to Nylon and P.V.D.F. However there are a number of technical problems associated with the plastic product from a temperature and pressure effect combined with the gas or material environment that currently exists. The research and development would aim to produce an improved product for the existing and new market areas. The benefits of producing a rubber product would enable much higher working temperatures to be used within the most arduous conditions for the benefit new oil exploration techniques. To produce a prototype manufacturing machine which has the capacity to produce a pipe of some 200 m long at an acceptable quality to satisfy the current market standards. The long length pipe when produced will have to withstand high pressures high temperatures and the passing of a variety of gases in a submersible atmosphere. Additionally the technology would benefit a Communication Market where long length rubber hoses would be beneficial. This technology will be developed for the benefit of an Italian Partner whom we are seeking to become part of the Research Programme.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Public risk perception and European U ion environmental policy' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

To investigate the influence of local cultural, socio-economic, historical, regulatory and other factors on the process of public perception of risks in order to help formulate and improve environmental policy instruments.OBJECTIVES: To investigate the influence of local cultural, socio-economic, historical, regulatory and other factors on the process of public perception of risks in order to help formulate and improve environmental policy instruments. DESCRIPTION: The focus is on the perception of risks posed by the chemical industry, in particular major accident hazard sites with significant environmental impact. The relationship between public perception and acceptance of risks, and how these attitudes can inform planning and other decision-making processes are investigated. A series of empirical studies are conducted in three European countries - the United Kingdom, Italy and Spain, using a variety of methods which combine qualitative and quantitative techniques. The project seeks to: i) examine the means to communicate risks to the public in a variety of cultural settings, affecting public attitudes and encouraging public participation in decision-making; ii) explore the effect of local knowledge in shaping and informing industrial risk management practices; iii) analyze the underlying processes influencing public demands, the exercise of choice, the formation of tastes, and the development of behaviour. This work has implications for the economic valuation techniques used in environmental policy. The project should yield new policy implications and the research findings will be applicable in the context of EU environmental policy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Research project for cokle fishing gear improvement and environmental impact reduction' to be submitted under Fifth Framework.

assistant: **Abstract**

Mechanical cockle fishery makes use of a suction dredging system that has been modified continuously in order to minimise damage to the product and by-catch. Further improvement to reduce sediment disturbance are promising but require a scientifically based technological approach. Improvement of the fishing gear and techniques is focused on the reduction of damage to the benthic environment, including sediment, benthos and juvenile cockles and aims for a better product quality (reduction of sand content and damage to the cockleshells). At present the main problem with technical improvement is the adjustment of the water jet in front of the gear and the transport of cockles on-board. The idea is to develop a more gentle flow and still achieve resuspension of cockles meanwhile minimising resuspension of sediment and biota, to develop a more gentle transport system to minimise sand content and damage to the cockle shells and to evaluate the yield as a function of effort.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The Writers and the Totalitarians: The Scandinavian-speaking Writers’ Associations in the European Schism, 1933-1953' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The Writers and the Totalitarians (WatTs) analyzes dynamics of great relevance to our current era by exploring how totalitarian cultural diplomacy and soft power was exercised, received, and negotiated by writers and intellectuals in the Scandinavian democracies during the political polarization that marked “the European schism” of the interwar, Second World War, and early Cold War years. The political and ideological dividing lines that came to define European political life with ever-greater starkness from the early 1930s onwards could not but make a mark on Scandinavian intellectual life. WatTs examines how the national writers’ associations in Denmark, Norway, and Sweden as well as the Swedish-speaking writers’ association in Finland reacted to and interacted with the German National Socialist and Soviet Communist regimes from 1933 and into the immediate post-war period. Despite their importance as fora for shaping, legitimizing, and discussing the attitudes and actions of Scandinavian-speaking writers, historical research has paid little attention to the writers’ associations, and even less to their roles and reactions vis-á-vis the epochal political, ideological, and cultural developments taking place in the Nordic countries’ Southern and Eastern neighbor states in the interwar years and beyond. By utilizing several understudied archival collections located across the Nordic region, which have never been studied in conjunction, WatTs heeds the transnational turn in historical studies and explores how the leaders and memberships of the Scandinavian-speaking national writers’ associations reacted to, interacted with, and positioned themselves vis-á-vis the Third Reich and the Soviet Union and their respective cultural diplomatic efforts, and how, in doing so, they b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'European iNitiative for Low cost, Innovative and Green High Thrust ENgine - Engine Demonstration' (ENLIGHTEN-ED).

assistant: **Innovation**

The space sector is a source of economic growth, jobs and exports, contributing to all Key Strategic Orientations of the EU strategic plan. Faced with growing competition and technological disruption, it is drastically vital to act in support of European space launchers development to preserve European independent access to space.European launchers must improve their competitiveness by halving launch price in the short term. In the long term, Europe will create common building blocks for an integrated and competitive European family of launchers of all scales with reusability functionalities. The purpose of ENLIGHTEN is to develop and test advanced production means and technologies for reusable rocket engines, following on the Prometheus® ESA program, in order to create a family of reusable, high-power engines fueled by bio-methane or green hydrogen.In the continuity of ENLIGHTEN, ENLIGHTEN-ED aims at maturate enabling technologies, subsystems, tools and processes by bringing them to TRL5/6. Then, ENLIGHTEN-ED will demonstrate the above technologies by engine on-ground demonstration tests by 2026 to reach TRL7.In the frame of ENLIGHTEN-ED, a tailored consortium (including major aerospace actors, SME, RTO and an university) will prepare a demonstrator of green high thrust engine (GTHE) based on liquid hydrogen using:-The latest advances in additive manufacturing to reduce the cost and number of engine parts,-Artificial Intelligence and machine learning to develop the first space engine health Monitoring System in Europe necessary to implement reusability,-New ultra-low-cost subsystems as engine ignition system, nozzle extension, electric valves and multi-functional lines.Therefore, ENLIGHTEN-ED will demonstrate the ability of such an ultra-low-cost engine to be rapidly o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'QUality and Effectiveness in Science and Technology communication' (QUEST).

assistant: **Concept**

Science Communication (SciCom) plays a key role in addressing today’s societal challenges. To be effective, it must be conceived as multi-directional communication, involving scientists, policy-makers, journalists, other communications actors and citizens. On one side, scientists produce research results but are not always equipped to communicate efficiently to the public and to policy-makers. On the other, journalists and other communications actors act as the interface between science, citizens and other audiences, although they may face challenges in fully comprehending the scientific message. Citizens will have a varied perception of the information received but limited knowledge and tools impeding a qualitative assessment. The variety of means of communication existing today makes communications faster and easier, but that increases the complexity of these interactions and the challenge to communicate “sound” science. We also need to consider that much of today SciCom passes through the digital sphere, as the advent of digitalization has changed the way in which information flows and opinions are shaped, also regarding science. Social media are one of the key representatives of these modern means of communication, deserving a special focus. In this context, the challenge faced by SciCom is in finding effective, non-hierarchical ways to exchange these diverse forms of knowledge, by making SciCom stakeholders interact in a constructive way through the different media. QUEST aims at facing this challenge with a multi-step approach that will: (1) understand the dynamics of today SciCom (2) design tools to evaluate SciCom quality (3) experiment best practices and proposing innovative ways for SciCom (4) promote SciCom training (5) build an engaging SciCom community. The
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Quantitative methods in stochastic homogenization'.

assistant: **Innovation**

This proposal deals with the development of quantitative tools in stochastic homogenization, and their applications to materials science. Three main challenges will be addressed.First, a complete quantitative theory of stochastic homogenization of linear elliptic equations will be developed starting from results I recently obtained on the subject combining tools originally introduced for statistical physics, such as spectral gap and logarithmic Sobolev inequalities, with elliptic regularity theory. The ultimate goal is to prove a central limit theorem for solutions to elliptic PDEs with random coefficients.The second challenge consists in developing an adaptive multiscale numerical method for diffusion in inhomogeneous media. Many powerful numerical methods were introduced in the last few years, and analyzed in the case of periodic coefficients. Relying on my recent results on quantitative stochastic homogenization, I have made a sharp numerical analysis of these methods, and introduced more efficient variants, so that the three academic examples of periodic, quasi-periodic, and random stationary diffusion coefficients can be dealt with efficiently. The emphasis of this challenge is put on the adaptivity with respect to the local structure of the diffusion coefficients, in order to deal with more complex examples of interest to practitioners.The last and larger objective is to make a rigorous connection between the continuum theory of nonlinear elastic materials and polymer-chain physics through stochastic homogenization of nonlinear problems and random graphs. Analytic and numerical preliminary results show the potential of this approach. I plan to derive explicit constitutive laws for rubber from polymer chain properties, using the insight of the first two challenges.