RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Time Resolved Single Molecule Spectroscopy Studies of Photoinduced Charge Separation and Charge Transfer in Model Photovoltaic Solar Energy Devices' under Sixth Framework.

assistant: **Concept**

The development of renewable energy - particularly energy from wind, water, solar power and biomass - is a central aim of the European Commission's energy policy. Renewable energy sources are expected to be economically competitive with conventional energy sources in the medium to long term.Many of the most promising strategies for solar energy conversion involve charge separation of an exciton in a photovoltaic device comprised of a nanostructured composite of various types. We propose to use novel single molecule (particle) modulation spectroscopy techniques to investigate photoinduced charge separation and charge transfer reactions in model photovoltaic solar energy devices based on nanoparticles. We believe that this general strategy will ultimately lead to new tools for photovoltaic device and materials research that will be single molecule spectroscopy (SMS) 'functional equivalents' for photo-electro-chemistry and ultrafast spectroscopy. In particular, this proposal takes a new direction in solar energy conversion research by developing and applying a new technique, Fluorescence Voltage-Time Resolved-Single Molecule Spectroscopy (FV-TR-SMS). This method involves simultaneous and synchronized SMS E-Field modulation, and light intensity modulation and/or pulsed lasers. Preliminary FV-TR-SMS results demonstrate that these methods are well suited to study the kinetics of photoinduced charge separation and transfer at the molecular level, and will allow us investigate in the proposed research critical unresolved issues regarding how charge separation and charge transfer processes depend upon chemical structure, morphology and the physical state (e.g. charging) of the layers and interfaces in the model photovoltaic solar energy devices.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Physiopathological investigation of animal models for disease : genotype-phenotype relationships'.

assistant: **Innovation**

Research training covers 10 areas of in vivo physiology such as heart, vascular, GI, kidney and lung, adapted to small (transgenic) animals. Also, measurements of blood pressure, echocardiography and scintigraphy and micro-biochemistry are performed.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Impact Shield A' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

This proposal is to design and manufacture an innovative shield to protect critical components of an aircraft against high velocity shrapnel from an engine burst.  The concept proposed here uses well established high performance fibres and manufacturing methods making it fit the requirements of medium to high maturity level and low manufacturing costs stated in the call.  However the combination of the latest development in quality of these materials and the fact that they meet the environment requirement as well as an innovative ballistic design takes the proposed shield concept beyond the state of the art.The proposal has come from a close collaboration between Imperial College Consultants and Swerea SICOMP.  It is therefore the result of the combined skills in manufacturing structural composites for the defence and aeronautical industry as well as specific ballistic design skills.  Both institutes have the necessary skills, experience and equipment to design and manufacture a successful shield.  As both these institutes are non profit research establishments actively working to advance composite technology, the materials and techniques have been chosen based on the type of treat and the aircraft integration constraints and there is no constrain to use any one particular material supplier.  Publishing and dissemination of the results is also not a problem if so desired.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'ProbeFix: an Innovative MedTech Solution  to improve the use of ultrasound for better Cardiac diagnosis in the EU' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Cardiovascular Disease accounts for 45% of mortality in Europe as a whole, a number which will increase as more and more people reach old age. In sonography, which is crucial in diagnosing CVD, up to 90% of professionals are experiencing work-related musculoskeletal disorders (WRMSD, also called RSI). There is evidence that 20% of sonographers suffering from WRMSD eventually suffer a career ending injury. This is highly undesirable, especially considering the ever growing demand for cardiac health care professionals.In 2016, new industry standards for the prevention of WRMSD in sonographers have been introduced, but these have not eradicated the problem. USONO has developed the ProbeFix, a fixation device for ultrasound probes, which removes the need to manually keep the ultrasound probe in place. This solution greatly improves sonographer’s working conditions, with the added benefits of increasing reproducibility of scanned images across different operators and patients, and significantly reducing the time an echo scan takes.USONO is will introduce the ProbeFix to the EU market in the next 1-2 years, quickly realizing an impact on cardiac health care and sonographer’s working conditions. There are over 100,000 cardiologists/sonographers in the EU, working in approx.. 10,000 hospitals and cardiac centres. These treat 49 million patients a year, a number that is steadily growing, with a total of over 75 million cardiac echography scans per year. USONO has started selling the ProbeFix in Europe. The main objective of this SME Phase 1 project is to explore and assess the possibilities of scaling-up the ProbeFix in the EU and eventually the rest of the world and bring it ultimately to TRL 9 in Phase 2. Furthermore, the business case and plan needs to be updated, elaborated
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Parasitic influences on an animal society' (SOCIALITY-PARASITISM).

assistant: **Concept**

Parasites are direct agents of natural selection, having significant effects on the reproductive success, life-history traits and phenotype of their hosts. Social insect colonies, by living in high density group of close relative individuals, offer favourable conditions for the spread of parasites. In response to infection, both infected and uninfected individuals exhibit behavioural changes that seem to reduce the risk of infection and the transmission of parasites. In order to shed new light on the interaction between social insect and their parasites we propose to study the consequences of ants' infection by two directly transmitted parasites a fungi and a bacteria. Trough comprehensive experimentation we will elucidate how infection affects host individuals and the whole colony at the chemical, behavioural and immune level. For the first time, we will explore the mechanisms responsible for the detection of infected individuals and the potential proximate causal link between the infection and the behavioural modifications. In addition, we will investigate whether changes in behaviour benefit the host as suggested by numerous studies or can be parasite adaptation aiming at increasing transmission. The proposed project will be the first to investigate whether ants immune response can be observed after exposition to chemicals extracted from infected individual. This multidisciplinary approach will significantly stimulate innovative and creative research in, for instance, providing insight into how group living may improve the survivorship of colony members despite the increased risks of parasite transmission that can accompany sociality
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Rewiring of ecological networks under global change' (ECONET) under Horizon Europe.

assistant: **Objectives**

One of the main consequences of the biodiversity crisis is the reorganization of ecological networks. This reorganization, usually termed ‘interaction rewiring’, can drastically alter nature’s functions and services to humanity. Therefore, predicting interaction rewiring is paramount to predicting the future structure, functioning and stability of the ecosystems. Until now this has not been done because quantifying and predicting rewiring into the future requires extensive data on species traits and interactions and computationally efficient and ecologically relevant analytical tools. The main objectives of ECONET are to quantify the potential of rewiring in mutualistic networks globally and to predict how mutualistic networks rewire due to global change (climate change, land cover change, human-driven extinctions). For this, I will use empirical data of pollination and seed dispersal networks to predict probabilities of all pairwise interactions in metawebs (network covering all possible pairwise interactions) with machine learning. I will quantify the species' rewiring potential as their interaction niche breadths in the metawebs. Then, I will construct scenarios of compositional change in local networks caused by global change and identify rewired interactions under different scenarios. I will also assess the stability and functionality of rewired networks under different scenarios. The main outcome of ECONET will be spatially-explicit knowledge of global change consequences on mutualistic networks. ECONET will provide practical and novel guidance to biodiversity management and conservation strategies, including nature-based solutions embedded in the EU’s environmental agenda. As a key part of ECONET, I will receive essential training from world-leading experts in th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Orphic Lithika : A New Edition' (2014-2020).

assistant: **Concept**

The Orphic Lithika constitute a short poem in hexameters (774 lines) about the miraculous virtues of 29 stones, the author and the date of composition of which remain unknown. The aim of my research is to provide an overall study of this relatively poorly studied text, which is still lacking today: a reliable critical text, a faithful translation of the poem accessible even to non-classicists, and an extensive historical-literary and philosophical commentary which sheds light on the exact significance of a little-known text and its context of production. The methodology and approach that I will implement for the constitution of the text, the translation and the commentary will be traditional. The most innovative aspect of my work will consist in the attempt to propose a new comprehensive interpretation of the poem, starting from the hypothesis of its composition at the end of the 4th century AD within the milieu of the pagan philosophers who were friends and followers of the emperor Julian (361-363) – also known as “the Apostate” due to his failed attempt to restore pagan religious traditions in a Roman Empire which, by his times, had largely become Christianized. This project will enhance my creative and innovative scholarly potential and enable me to diversify my individual competence in terms of new skills acquisition, thanks to advanced training and international mobility. This would by in full conformity to the spirit and mission of the Marie Curie actions.


**Keywords:** Late Antiquity, Byzantine Studies, Emperor Julian, Neoplatonism, Inter-religious Debate, Orphic Literature, Didactic Poetry, Magic Stones
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Entwicklung eines modularen steuerungs- u. diagnosesystems auf 32bit-basis' in the context of a Fourth Framework call.

assistant: **Objectives**

The goal of our company is to conceptualize and develop a 32 Bit controller system which aside from normal control tasks can also carry out data analysis and make prognoses from this analysis. It will be a modular controller with locally operating components, networked over a field bus system, to allow a higher functionality of measuring, controlling, adjusting and testing. Our principal will consist of an electro/magnetic field proof, zero potential core which will contain 1 to 16 control modules. The individual modules will be connected by fiber optic cables. The connection to a PC or Notebook will also take place. Appropriate interfaces for high level programming languages is planned. The development of the software, hardware and other devices (e.g. Bus/system, sub/modules, interfaces are to be included in this undertaking. The cost advantage accompanying the use of this concept will put SME's in the position to increase productivity and market competitiveness. The controllers will be produced by our company and the partner companies in the other countries after further development and could be applied in a wide range of applications. The goal of our company is to conceptualize and develop a 32 Bit controller system which aside from normal control tasks can also carry out data analysis and make prognoses from this analysis. It will be a modular controller with locally operating components, networked over a field bus system, to allow a higher functionality of measuring, controlling, adjusting and testing. Our principal will consist of an electro/magnetic field proof, zero potential core which will contain 1 to 16 control modules. The individual modules will be connected by fiber optic cables. The connection to a PC or Notebook will also take place. Appropriate interfa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'PyroLife - training the next generation of integrated fire management experts' under Horizon 2020.

assistant: **Concept**

2018 was a glimpse of the future: deadly mega-fires in Mediterranean and numerous wildfires in temperate and boreal regions. Traditional mono-disciplinary attitudes cannot solve this challenge: there is a critical need to change management paradigms from fire resistance to landscape resilience: Living with Fire. PyroLife trains the new generation of interdisciplinary experts in holistic integrated fire management, through knowledge transfer between South and NW Europe and application of lessons learned in prevention of floods and other risks. Our unique integrated training program, crucially developed with industry, provides 15 ESRs the in-depth, interdisciplinary, integrated and transferable knowledge and skills required to complete their research and maximize future employability. Individual projects target risk quantification (fire danger, vulnerability, (mega)fire behavior, environmental and economic impacts), risk reduction (fire resilient home, garden and landscape design, prevention and governance), and risk communication (stimulating stakeholder and community resilience and preparedness). PyroLife is original for its inter- and transdisciplinary, intersectoral, cross-risk, and cross-climate approach to training doctoral students and tackling wildfire challenges, connecting 21 diverse partners. The project structures doctoral training by being the first large and integrated doctoral training program on wildfires globally, being a leading example for training of our future leaders. With an exemplary gender balance and diversity in industry and academia, PyroLife combines excellent research and supervision to make an impact on society and economy, through broad dissemination and communication. With the Commission’s Nov 2018 call for integrated fire management to ‘t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'The Impact of Callose Metabolism on the Mechanical Properties of Cell Wall during Tomato Ripening .'.

assistant: **Concept**

Tomato, SolanTomato, Solanum lycopersicum L. is one of the most important crops and an important source of nutrients in the world. However, around 25-42% of the yield are lost during postharvest. Rapid softening is one of the main causes reducing the shelf-life of the fruit. Therefore, delaying this process is one of the major targets in fruit breeding programmes. Evidence show that stimulating callose in tomatoes via bruising or heating induce changes in fruit texture. In this project, the impact on fruit softening of cell wall modifications targeting the synthesis/degradation of the beta 1,3 glucan component (named callose) will be investigated. The aim is to determine how changes in callose accumulation at the latest stages of fruit development modify the texture, the structural and mechanical properties of tomato fruit. Introgression and transgenic lines with modified callose metabolism will be generated and cell wall biochemistry and mechanical properties will be characterized combining cross-disciplinary approaches such as immunolocalization, Fourier-transformed infrared, nano and macro indentation and Raman spectroscopy. Moreover, the impact of callose modifications on plant/fruit development and on other processes related to softening (such as water content or pathogen susceptibility) will be determined.The results of our project will provide novel molecular tools to use in the selection and breeding of fruit varieties. As a direct outcome, we expect to obtain plants producing fruits that maintain their firmness for a longer period of time, thus with reduce susceptibility to mechanical damage and pathogen attack during the postharvest period. This achievement will have a positive impact on the European Union economy by optimizing processes such as the frequency
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'LSE TECHNOLOGY APPROACH TO GENERATE INNOVATIVE KINASE INHIBITOR DRUGS'.

assistant: **Concept**

Over the last decade, kinases have emerged as attractive therapeutic targets in inflammatory diseases. Numerous efforts in the pharmaceutical community are directed towards the discovery of small molecule inhibitors that regulate kinase function.A number of issues need to be addressed when considering kinases as targets in inflammation. The combination of efficacy and favourable safety profile is often key for the successful treatment of chronic inflammatory and/or autoimmune diseases with kinase inhibitors.The LSE (Low Systemic Exposure) approach is a Creabilis proprietary technology that generates innovative molecules with unique physico-chemical and pharmacological characteristics. LSE molecules are ‘topical by design’ molecules that share some common features. They combine high local concentration with poor systemic absorption and distribution. If absorbed, LSE molecules are rapidly eliminated from the systemic circulation (very short plasma half-life), thus generating no/low side effects. LSE approach has already been clinically validated through CT327, a selective topical kinase inhibitor that recently reported positive Phase 2a data in both psoriasis and atopic dermatitis.This project will combine Creabilis experience and know-how on LSE modification of molecules with the sound systems biology and network pharmacology expertise of the University of Dundee to generate and bring to preclinical development a new generation of innovative molecules optimised for topical treatment of inflammatory diseases, such as psoriasis, atopic dermatitis and inflammatory bowel disease.The generated lead compound(s) will be characterized by minimal or no systemic toxicity combined with efficacy and optimised selectivity. This would tremendously widen the range of patients affected