RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'European scenarios on transport - energy - environment for metropolitan areas' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Objectives Integrating available macroeconomic and urban models with land use models to assess impacts on transportation and analyzing the downstream chain transportation - energy - emissions - dispersions. The aim is to provide local government, civic groups, private and public planners with a set of tools fit to analyze the consequences of plans and policy decisions to optimise/improve existing urban and suburban situations - as illustrated in section 3 below. Technical Approach Existing macro and micro models are reviewed and integrated to analyze future prospects of the chain: socio-economic conditions - land use - transportation supply/demand (disaggregated public/private and different modes) - energy use - emissions output and dispersions and their monitoring. A co-operative effort of participants is carried out to integrate different models and make them compatible with each other, more significant, apt to produce better forecast and policy assessments. Expected Achievements and Exploitation Validation of models chains based on application of data collections, surveys and mathematical models to actual situations in: Rome, London, Brussels, Lyon. Tools produced and/or refined usable for impact and sensitivity analysis of policies: industrial and business, land use and regulation, traffic disciplines and investment in infrastructures, public transport, technology developments of low or zero emission engines and possible enforcement of their adoption. Scenarios produced in different hypotheses of tomorrow's car features and future acceptance and adoption, will be assessed in more detailed and realistic ways. This will produce a feedback to be used in computing cost/benefit assessments and forecasting penetration of different models of tomorrow's car in European mark
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Earth observation and Earth GNSS data acquisition and processing platform for safe, sustainable and cost-efficient mining operations' (Goldeneye) targeting Horizon 2020.

assistant: **Abstract**

The Goldeneye project will implement a unique combination of remote sensing and positioning technologies, exploiting Earth observation and Earth GNSS data, together with data fusion and processing powered by data analytics and machine-learning algorithms. The platform will allow satellites, drones and in-situ sensors to collect high-resolution data of the entire mine, which can be processed and converted into actionable intelligence for safety, environmental monitoring and overall productivity, allowing more efficient exploration, extraction and closure. These tools will be demonstrated in 5 field trials in Germany, Bulgaria, Romania, Kosovo and Finland, creating a compelling value proposition for implementation across the mining industry value chain. The project has a duration of 3 years and an EC funding of €8.36M. The consortium includes a large industrial partner, 7 SMEs, 4 academic/research centres and 4 end-users, supported by a strong advisory board of experts in geosciences.


**Keywords:** data fusion, extraction, exploration, closure, safety, sustainability, economics
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Regular and Exotic behavior in Hamiltonian and low-dimensional dynamical systems'.

assistant: **Concept**

REXHALODYN aims at understanding some of the regular and exotic features of Hamiltonian systems, circle maps, and generalized interval exchange transformations, or GIETs. Hamiltonians provide a powerful description of classical mechanics phenomena. Circle maps and GIETs are archetypal examples that illustrate fundamental concepts and phenomena within dynamical systems. Moreover, the latter two offer simplified models that capture essential features of more complex systems; e.g., they appear naturally as Poincar maps of (locally) Hamiltonian flows on compact surfaces, and thus are closely related to Hamiltonians in this context. Within this framework, the words regular and exotic do not have a precise mathematical meaning; however, we use them here to stand for features in each system that are either well-behaved (regular), such as the existence of stable quasi-periodic motions in Hamiltonian, and rigidity phenomena in circle maps and GIETs; and for features that are ill-behaved (exotic), such as sensitive dependence to initial conditions in Hamiltonians or existence of singular invariant measures in circle maps and GIETs. Understanding these complementary features deepens our understanding of the systems, their properties, and the underlying mathematical structures that give rise to a rich spectrum of behaviors.The main objectives of this project are:-Prove the existence of lower-dimensional invariant tori, associated with a resonant torus with any number of resonances, for general classes (e.g., convex) of near-integrable Hamiltonians.-Obtain precise estimates for the Hausdorff dimension of the unique invariant probability measure of multicritical circle maps with irrational rotation number of bounded type.-Obtain rigidity results for multicritical circle maps with irr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Dynamic protein interaction networks in cancer' (ONCOPROTNET), addressing dissemination and exploitation.

assistant: **Impact**

The inappropriate activity of signaling pathways and activation of gene-expression programs is a primary driver of transformation in cancer cells. In turn, dis-regulation of signaling pathways in cancer cells is frequently caused by mutations in important oncoproteins, which may alter protein expression, structure or function. In addition, increasing evidence shows that oncoprotein mutations may alter the interactions of oncoproteins with other proteins, causing wide-spread perturbations to the network of proteins in the cell. Although high-throughput sequencing techniques are rapidly identifying large volumes of mutations from tumor samples, our understanding of how these mutations transform cancer cells, and more specifically how they perturb protein-protein interactions is lagging behind. This proposal describes novel proteomics and computational techniques directed at understanding how mutations in important oncoproteins disrupt or alter protein-protein interactions, and how these alterations lead in turn to dis-regulation of signaling pathways and gene-expression programs. The work described here focuses on oncoproteins in the Wnt signaling pathway, but importantly, the techniques described are widely applicable, and have the potential to provide a powerful means of elucidating protein interaction networks in cancer cells. The broader impacts of this work include the potential identification of novel colorectal cancer therapeutic targets as well as mapping protein networks in cancer cells, so that in future the wider effects of therapeutics in the cancer cell can be better understood.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Etude et developpement d'un procede de decapage et decalaminage des fils et tubes metalliques par jet d'eau THP'.

assistant: **Objectives**

The industrial problem to be solved is to produce a descaling and decarbonisation system for continuous metal wires and tubes in place of present processes: chemical and mechanical. The present constraints of the processes are: deterioration of materials, harm to the environment, danger for user personnel and productivity restrictions caused by stops in the manufacturing cycle. The industrial objective is therefore to integrate the system to be developed into the manufacturing process to increase productivity while reducing technological and environmental harm. The research work will qualify the high pressure technology, define the process, analyse its mechanical behaviour and define its technological and environmental performance.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Interactions between oxidative stress and the activation of mitogenic signalling in alzheimer's disease' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

Alzheimer's disease (AD), the leading cause of dementia in the elderly, places an increasing medical, social and economic burden on the European society. Neither treatment nor possibilities to prevent or delay the onset of the disease are available. The present multidisciplinary approach to be conducted as a multicoated study of eight groups on a European scale combines expertise in molecular biology, genetics, neurochemistry, neuromorphology, neuropharmacology, neurophysiology and behavioural biology. Interactions between oxidative stress as a major driving force of degeneration and the activation of mitogenic signalling as a critical trigger of neurodegeneration in AD modified by interactions and epistemic effects of AD-related genes will be studied. Research will be based on new models of the disease that allow to analyse the genetic, molecular and cellular mechanisms underplaying neurodegeneration, to identify molecular switches that critically determine the fate of a neuron after injury and to test potentially protective strategies. Aiming at the definition and design of a future rational and effective prevention and/or treatment of AD, anticipated deliverables will contribute to an improvement of the quality of life of the aging population.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Concerted action on seroconversion to AIDS and death in Europe' under Sixth Framework.

assistant: **Concept**

CASCADE was established in 1997 as a collaboration between the investigators of 22 cohorts of persons with well-estimated dates of HIV seroconversion (seroconverters). It is currently a network of epidemiologists, statisticians, virologists and clinicians from lead HIV institutions in 13 European countries, Australia and Canada. Seroconverters are enrolled into the individual cohorts locally and nationally and are typically followed up life-long. CASCADE's main aim is to monitor newly infected individuals, as well as those already enrolled in studies, over the entire duration of HIV infection.The main premise is that through pooling data we are able to address issues which cannot be reliably addressed from single studies alone. Our main objectives are to: estimate survival expectations and assess changes over time; assess the impact of adverse drug reactions on survival, particularly if therapy is started close to seroconversion, and monitor changes in the cause of death over time; examine any changes in the characteristics of the virus over time; determine the impact of transmitted resistance, virus subtype, and host genetic factors on response to therapy and clinical outcome; characterise the foci of recent HIV epidemics in Eastern Europe; characterise initial disease progression in new epidemic areas; examine the effect of co-infection on HIV disease and response to therapy; and develop new techniques to facilitate the co-ordination of HIV clinical research across European cohorts.Follow-up data from seroconverters are unique in providing information from an individual's initial contact with HIV as events can, therefore, be related to roughly the same fixed time point in their disease. Seroconverters thus provide a unique opportunity to study HIV throughout its whole
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'VALIDATION OF A FOUNDRYMAN'S DESIGN SYSTEM FOR THE SIMULATION OF CASTING PROCESSES'.

assistant: **Concept**

The project aims to adapt and validate the finite element program VULCAN so that it can be effectively and easily applied by foundry engineers to the design and analysis of industrial cast parts and casting processes. Casting is a complex process and the program VULCAN employs state-of-the-art techniques to simulate the coupled thermal-mechanical solidification and cooling behaviour of the casting process.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Quantum Simulator with Hot Atomic Vapors'.

assistant: **Innovation**

In the context of the ongoing development of novel quantum technologies, includingquantum sensors, quantum communication, quantum simulators and quantum computing,some devices are mature without resorting to the powerful but fragile entanglement between qubits.Exploiting the wave nature of devices, photons often play an important role. In order to enlarge thepotential of photonic devices, controlled atom-photon interactions will be pushed to new limits in orderto build analog and digital wave simulators. In the present project,these interactions are mediated via photon-atom coupling using room temperature cells of atomic vapours.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'A synthetic biology approach for T cell exhaustion' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

Synthetic Biology has revolutionised approaches for several scientific, industrial and medical applications. These include the development of immunotherapies based on bioengineered cells, most notably engineering of patients T cells with tumor-targeting receptors, the CAR-T cells. Cell-based immunotherapies have shown remarkable clinical success; yet, long-term benefits are hampered by dysfunction of T cells occurring following antigen chronic exposure, a process known as T cell exhaustion. Current treatments of T cell exhaustion are limited and exhibit adverse effects.       Synthetic T-rEX aims to reprogram exhausted T-cells using synthetic biology circuits, to implement enhanced and more effective immune cell-based therapies. We will develop specific, self-contained genetic circuits with improved capabilities that minimise the impact on normal cell physiology; by pre-programmed integration of exhaustion-specific intracellular signals, these will rewire T cell activity and restore normal function. Circuits will be developed using a stepwise, bottom-up approach to identify exhaustion-specific inputs by RNA and microRNA-sequencing profile performed on ex vivo exhausted human CD8+ T cells. We will then design (a) synthetic promoters and (b) microRNA-regulated 5’UTR that will compute information processing to trigger output activation. Localised therapy will rely on concerted action of genetically encoded immune-checkpoint blockade and fine-tuning of epigenetic modulators that play a major role in T cell exhaustion. Finally, we will engineer T cells with sensor-actuator synthetic devices that revert exhaustion (T-rEX cells). In summary, our proposal provides a paradigm shift in the development of strategies against T cell exhaustion and a solid break-through towards enhan
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Fate and toxicity of allelochemicals (natural plant toxins) in relation to environment and consumer' (FATEALLCHEM).

assistant: **Innovation**

In recent years there has been an increasing focus on the prospects of exploiting allelopathy as an alternative strategy for controlling weeds, insects and diseases. However, the environmental and toxicological consequences of this should be investigated. The objective of the present project is to perform an environmental and human risk assessment of exploiting the allelopathic properties of wheat in modern farming and to develop a framework for future assessments of allelopathic crops. Well-described allelopathic properties of wheat combined with low environmental persistence and low toxicities will enhance the possibilities for farmers to make a sound production. If the evaluation of environmental persistence and human as well as environmental toxicities shows that the allelochemical compounds constitute a higher risk than the risk of low doses of synthetic pesticides, new views must be put on exploiting allelopathy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Boosting female entrepreneurship through joint services and activities' (Womenture), addressing dissemination and exploitation.

assistant: **Impact**

The 24-month Womenture project aligns its efforts with the European Commission's objective to create interconnected, inclusive and more efficient innovation ecosystems across Europe that draws on the existing strengths of European, national, regional, and local ecosystems and pulls in new, less well-represented stakeholders and less advanced in innovation territories, to set, undertake, and achieve collective ambitions towards challenges for the benefit of the society, including green, digital, and social transitions. The overall objective of the project is to empower innovation agencies and accelerators to generate and embed new joint services and activities into their initiatives to boost female entrepreneurship and women innovation in the participating ecosystems. The consortium brings together innovation agencies and accelerators from strong, moderate, and emerging innovator regions with the aim to support women innovators, spread the entrepreneurial mindset, present them the already existing initiatives of the partners, projects, and networks dealing with women innovators and connect each other. Through the delivery of its activities (co-creation, co-design, co-assessment, capacity building, business support programme, innovation ecosystem hub creation), the project will result in enhanced connections, strengthened and more effective capacity of innovation ecosystem actors, improved visibility and increased involvement of women innovators in innovation initiatives towards economic development and growth.


**Keywords:** Women innovation, startup, innovation ecosystem, training, mentoring, visibility, inclusivity, interconnection