RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'INTEGRATED AND ECOLOGICAL VEGETABLE PRODUCTION, DEVELOPMENT OF SUSTAINABLE FARMING SYSTEMS FOCUSING ON HIGH QUALITY PRODUCTION AND MINIMUM ENVIRONMENTAL IMPACT' under Fourth Framework.

assistant: **Concept**

Objectives- to develop more sustainable integrated and ecological vegetable farming systems that integrate high.quality production with minimal environmental impact by using a comprehensive coherent and strategic standardised novel methodology called the lprototyping of integrated and ecological farming systems, resulting from an EU concerted action on this topic for arable farming ending in 1996.- to develop in this framework multi-objective farming methods concerning crop rotation, fertilisation, crop protection and nature and landscape management that enable integration of potentially conflicting objectives like economy and ecology.- to elaborate novel approaches to pesticide use evaluation and pesticide selection, the quality production of crops, the energy use of off farm inputs and the farm economic perspectives- to integrate all the elaborated knowledge in comprehensive, coherent farming methods manuals to be used by the farming industry, research, extension and education- to compare in a comprehensive and standardised way ecological and integrated farming systems.DescriptionThe farms that produce field grown vegetables are relatively small, mostly concentrated in certain regions (for practical market-oriented reasons) often highly specialised and characterised by the very intensive land use (all year round soil utilisation) and high (extemal) labour demand per hectare. Vegetable growing is facing increasing agronomical, environmental and economical problems. Farmers are currently challenged by consumers and authorities to be the responsible manager of the green space, the rural area while producing high quality (even speciality) products. This affects the full depth and scale of the farm management. Consequently there is an urgent need for new farming systems th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Targeting Acute Leukemia with TdT-TCR-T-cell therapy' (TTT-therapy) targeting Horizon Europe.

assistant: **Abstract**

The aim of this PoC project is to commercialize new therapy for acute lymphoblastic leukemia (ALL) developed in context of my ERC consolidator grant. T-cell receptors (TCRs) have in recent years emerged as promising therapeutic molecules in cell- and gene-therapy of cancer. I have completed the pre-clinical validation of a TCR that recognizes an HLA-bound peptide from a novel target, the nuclear enzyme terminal deoxynucleotidyl transferase (TdT-TCR). In vitro and in vivo data from four different mouse models show eradication of ALL and no indications of toxicity. T-cells genetically modified with the TdT-TCR effectively kill lymphoblastic cancer cells while sparing healthy B and T-cells, myeloid cells and hematopoietic stem cells. Funding has been secured for an investigator-initiated trial to determine safety and explore efficacy of TdT-TCR-T-cell therapy – TTT-therapy. The trial will recruit ALL patients relapsing from/refractory to standard therapy, who have a dismal prognosis and thus a great unmet medical need. To facilitate commercial development, I have created a start-up company and secured the company exclusive licenses for the patents on the TdT-TCR and the technology used for the development, on which I am the main inventor. In the proposed ERC PoC project, I and my strong team of advisers with expertise in the business development, clinical development, IPR and financial aspects needed for commercialization, will conduct a market analysis for TTT-therapy and develop an IPR and business strategy for the start-up company. Since several studies report expression of TdT in acute myeloid leukemia (AML), I will conduct laboratory research to determine if the TdT-TCR can also mediate killing of AML cells. AML patients have an overall 5-year survival of only 30% and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Configurational Mechanics of Soft Materials: Revolutionising  Geometrically Nonlinear Fracture' (SoftFrac), addressing dissemination and exploitation.

assistant: **Impact**

SoftFrac will revolutionise geometrically nonlinear fracture mechanics of soft materials (in short soft fracture) by capitalising on configurational mechanics, an unconventional continuum formulation that I helped shaping over the past decades. Mastering soft fracture will result in disruptive progress in designing the failure resilience of soft devices, i.e. soft robotics, stretchable electronics and tissue engineering applications. Soft materials are challenging since they can display moduli as low as only a few kPa, thus allowing for extremely large deformations. Geometrically linear fracture mechanics is well established, nevertheless not applicable for soft fracture given the over-restrictive assumptions of infinitesimal deformations. The appropriate geometrically nonlinear, finite deformation counterpart is, however, still in its infancy. By combining innovative data-driven/data-adaptive constitutive modelling with novel configurational-force-driven fracture onset and crack propagation, I will overcome the fundamental obstacles to date preventing significant progress in soft fracture. I propose three interwoven research Threads jointly addressing challenging theoretical, computational and experimental problems in soft fracture. The theoretical Thread establishes a new constitutive modelling ansatz for soft in/elastic materials, and develops the transformational configurational fracture approach. The computational Thread provides the associated novel algorithmic setting and delivers high-fidelity discretisation schemes to numerically follow crack propagation driven by accurately determined configurational forces. The experimental Thread generates and analyses comprehensive experimental data of soft materials and their geometrically nonlinear fracture for properly c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'WIDENING HIGH-THROUGHPUT PLANT PHENOTYPING ACROSS EUROPE: ADVANCING COLLABORATIVE KNOWLEDGE EXCHANGE AND TECHNOLOGY TRANSFER', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

PHENOWEX aims to enhance the scientific excellence and innovation capacity of two widening institutions from the Mediterranean Region, namely EGE (Türkiye) and CYENS (Cyprus), in the field of High-Throughput Phenotyping (HTP) with the assistance of top-class leading partners from across Europe. PHENOWEX will use the appropriate methodology to reach its four objectives which are; i) To enhance the scientific excellence level of widening countries, ii) To create a Sustainable network, integration, and dissemination, iii) To improve the innovation capacity of the widening countries via real-world pilot studies, and iv) To improve the project management and administration skills of widening partners. The widening partners, EGE and CYENS, will receive support from Wageningen Research (WR), the National Research Council of Italy (CNR), and Forschungszentrum Jülich GmbH (FZJ). These institutions possess outstanding scientific excellence and innovation capacity in high-throughput phenotyping (HTP) and plant physiology. The expected outcomes arising from the PHENOWEX entail a multifaceted enhancement of scientific excellence in HTP research within these widening countries. This involves the establishment and fortification of collaborative networks with vanguard organizations (e.g. EMPHASIS) currently at the forefront of this technology. Additionally, the project aspires to cultivate creativity and amplify the capacity for international project management in the context of HTP research, thus encapsulating the overall ambit of anticipated improvements. Moreover, one of the unique aspects of PHENOWEX is that it serves as a testament to the power of science diplomacy and international cooperation. While political issues persist between Cyprus and Türkiye, the collaboration between C
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Integrated approaches to study gene regulation during cellular differentiation' under Seventh Framework.

assistant: **Concept**

Cellular differentiation from stem cells to fully functional mature cells is a multi step process executed by complex transcription programs. Once differentiated, cells must faithfully maintain their identity through cellular memory mechanisms. The utilisation of genetic information stored in linear DNA sequence occurs within the three dimensional context of chromatin, chromosomes and the nucleus, all of which contribute to gene regulation mechanisms. The main aim of this ITN is to get a comprehensive view on the mechanisms controling gene expression during cell differentiation by integrating studies on multiple regulatory levels from DNA binding transcription factors through to nuclear organization. We will take a multi-faceted approach addressing the functions of: (i) transcription factors and their co-factors (ii) chromatin domains and histone variants, (iii) epigenetic mechanisms of cellular memory and identity, (iv) global gene interactions in nuclear space and (iv) nuclear territories of gene activity. Genomics approaches will be employed to describe global changes in gene target networks and gene interactions in the nucleus during ES cell differentiation into the hepatic, neuronal and hematopoietic lineages. Proteomics will be employed for the characterization of transcription factor and epigenetic modifying complexes and of the in vivo protein composition of specialized chromatin domains. The research activities of this ITN are organized in the context of a multidisciplinary Training Program, which provides unique opportunities for the training of early stage researchers to address fundamental biological questions with far reaching implications in biotechnology and human health.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Protection and Resilience Of Ground based infRastructures for European Space Systems' (PROGRESS), addressing dissemination and exploitation.

assistant: **Impact**

PROGRESS will focus on improving the security and resilience of Global Navigation Satellite Systems (GNSS) and its results will also be applicable to earth observation infrastructure and assets. At the start of the project a generic GNSS system will be designed and its associated augmentation system will be assessed with regards to vulnerability from selected attack threat risk scenarios. PROGRESS will focus on those threats that are likely to increase in the coming years, for instance new terrorism attacks from highly educated terrorists. The resulting prioritisation of threats and scenarios will be used as input to develop a prototype Security Management Solution (SMS). PROGRESS SMS will be a centralized solution able to automatically detect attacks with a built-in reconfiguration capability allowing to ensure the overall system Quality of Service. PROGRESS SMS will be composed of an Integrated Ground Station Security Monitoring System (IGSSMS) and a Security Control Centre (SCC). The IGSSMS will be an innovative monitoring solution for the detection of cyber attacks, Radiofrequency (RF) attacks and physical attacks. The Security Control Centre will analyse the impact of the reported attacks on the system performance and Quality of Service (QoS) and will propose mitigation strategies, including automatic system reconfiguration. The SMS will be developed with full consideration of present methods and measures for the security and resilience of complex interconnected space control ground station networks by present operators of Ground Mission segments (GMS) and Ground Control systems (GCS). The consortium includes the operator the Galileo Control Centre in Oberpfaffenhofen, the European leader for satellite systems, a manufacturer and world distributor of security solut
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Designing and Developing Wearables for Virtual Reality Environments with a Research Through Design Process' (WEARTUAL), addressing dissemination and exploitation.

assistant: **Impact**

In WEARTUAL, I will investigate and develop ways to integrate wearables into virtual reality (VR) environments in a way that enhance the immersiveness of the VR experience. In particular, I will investigate the possible functions and interaction modalities of wearables for providing an improved user experience in VR by developing prototypes and including users in the design process. As a result, I will obtain wearable prototypes, comprehensive user experience data and design guidelines that will inform the human-computer interaction (HCI) literature about the right ways  for designing wearables for VR environments. WEARTUAL is a user-oriented research through design project that will adopt an interdisciplinary approach by using the disciplines of interaction design, game design, product design, engineering and psychology. Mainly, I will adopt a research structure that encapsulates user inclusion, ideation, prototype development and user experience experiments and evaluations. In this project, I will transfer my knowledge of designing games, wearables and prototyping for design research activities, while supervision of Prof. Juho Hamari (Tampere University, Finland) will contribute to game design and gameful experience measurement. Prof. Hamari leads the Gamification Group (GG), an interdisciplinary team composed of 18 members whose research is focused on game research, gamification and immersive technologies, such as virtual and augmented reality. In this sense, his experience in leading complementary research teams will also help me develop as a leader for directing research groups. I will also closely collaborate with the members of the GG who are experienced in conducting research on and developing VR content.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The European correspondence to Jacob Burckhardt' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The aim of this project is to map and publish in a critical edition the extensive correspondence of European intellectuals with the Swiss cultural historian Jacob Burckhardt over a period of more than half a century, from 1842 to 1897. This correspondence documents a crucial period in European history and culture, one which witnessed the emergence of art history as a separate discipline; serious political conflict in France, Germany, Italy and Switzerland; the birth of the nation-states of Italy and Germany; debate on the meaning and consequences of democracy as a system of government; and the rise of Caesarism in France. The effects of modernism are also discussed in this correspondence, from the culture of museums, art exhibitions and the first universal expositions (e.g., the Expositions Universelles in Paris) to the clash between industrial culture and neo-humanist ideals of education. The large body of correspondence received by Jacob Burckhardt (about two thousand letters conserved in various libraries and private archives) provides a cultural map of this crucial phase in the development of a new European identity.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'EuroMedMig PhD Network'.

assistant: **Innovation**

EuroMedMig PhD Network creates a sound community of leading DCs based on research excellence and following core research principles, being EuroMedMig the Interdisciplinary Research Network on Migrations in the Mediterranean coordinated by UPF, and its philosophy being that of promoting multilateral knowledge co-production on Migrations while ensuring geographic representativity and plurality of perspectives and disciplines. Against this background, 10 leading universities from all rims of the Mediterranean have joined efforts and engaged in this DN, which represents a quantum leap in training the next generation of researchers taking the Mediterranean as a regional scale of analysis. More specifically, this DN revolves around 3 main pillars: promoting research excellence; developing advanced training for DC, including methodological, ethical, conceptual and transferable skills training aiming at leveraging career prospects, and promoting inter-academic stays; and fostering policy and social dialogues by favouring policy-oriented research capable of influencing the scientific and the political debate in line with EUs Euromed agenda. Regarding the latter, this DN seeks to establish connections with relevant multi-scale stakeholders and highly impactful policy recommendations will be produced. In turn, these efforts will enhance the role of Academia, and in particular, Academic Networks, in initiatives at the nexus of research, governance and policy. In particular, DCs will be able to develop their individual research projects in the following themes: Governance, policies and politics, taxonomies of motions and drivers of migration, social and cultural transformations, and economy and labour market. These themes will also guide all EuroMedMig PhD Networks training cumulati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Sonarc - The world's first full audio frequency range, massless speaker technology platform, providing immersive and powerful sound from a smaller size.' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Sonarc Innovations have created the world’s first full audio range speaker technology without any moving parts, providing clarity immersive and power sound from a smaller size whilst reducing manufacturing costs and complexity. Sonarc Innovations are targeting the €17Bn home audio market, with the ambition of becoming the new standard in speaker driver technology, providing precisely controlled panels of micro speaker devices for the accurate creation of immersive, high spatial resolution sound environments, allowing listeners to experience a richer and realistic sound, when compared to today's bulky, low spatial resolution speaker technology. Sonarc Innovations is applying for the Horizon 2020 programme under the ‘Innovation in SME’s’ SMEInst-01-2016-2017 Open Disruptive Innovation Scheme phase 1, the overall objective for this innovation project is to bring to market a novel and inventive speaker technology with industrial applications (as stated in the written opinion of PCT international patent search authority August 2017 on Sonarc technology) superseding existing speaker driver technology across a wide range of user applications from immersive audio to portable devices. Revenue from licensing/partnership APT for specific applications will finance ongoing EU based innovation at Sonarc Innovations, enabling the creation of high value, knowledge based employment. This will allow the EU to stay at the forefront of this emerging and expanding technological field and area of research. Sonarc Innovations will focus on the development of new and innovative commercial applications for the APT, including miniaturisation for portable and mobile devices, creation of omnidirectional and directional products, optimization of existing technology around power efficiency and sound