RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'MOtorized NAnomachines: fundamentaLs, InnovationS, Applications'.

assistant: **Objectives**

MonaLisa, a pioneering European consortium, is at the forefront of artificial molecular machine research, setting the stage for breakthroughs in chemical synthesis, nanotechnology, medical treatment and smart materials. Building on the foundational work recognised by the 2016 Nobel Prize in Chemistry, MonaLisa aims to make groundbreaking discoveries in the design and functional control of molecular machines that will lead to first demonstrations with practical relevance. At the heart of MonaLisa is an innovative training programme. Fifteen doctoral candidates will receive comprehensive mentoring and training to become future leaders in the field. The programme is designed to foster not only academic excellence but also entrepreneurial skills, enabling these professionals to translate scientific breakthroughs into innovations and support evidence-based decision-making. The strength of MonaLisa lies in its joint vision and collaborative framework, bringing together top scientists, including four Nobel laureates, prestigious institutions and a wide range of industry partners. The non-academic support ranges from dynamic SMEs to large global players, supported by leading organisations that act as multipliers, fostering new programmes and partnerships. Looking to the future, MonaLisa is committed to developing sustainable, educational structures that integrate the non-academic sector to cultivate skills essential for the academic and non-academic workplaces of the 21st century. This initiative will increase collaboration, research intensity and innovation capacity within the European chemistry ecosystem. In doing so, MonaLisa is poised to secure Europe's leadership in science and technology, driving economic growth and societal benefits.


**Keywords:** Molecular motors, Nan
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Automatic manufacturing of lasts for the footwear industry'.

assistant: **Innovation**

Last manufacturing process are based on the use of machines that copy a model and are able to produce at the same time 1 or 2 pairs of lasts. Current technologies, from USA,, are only able of manufacture a last from electronic data (digitised last), but are not linked with any CAD system and doesn't offer good accuracy, as they don't finish the toe and back part of the last, that must be hand-made. The present proposal defines the concept of a new system that, integrated with a CAD one and a digitiser device, will be able of manufacture a whole last, comprising the toe and back part, thus avoiding lack of accuracy and improving repeatability of last manufacturing machines. The consortium responsible is composed by a last manufacturer and a components manufacturer for the footwear industry, which also manufactures last. The research to be done is in the field of automation and integration of CAD/CAM systems. A new control for the machines must be developed and the link between it and the CAD and digitiser device developed, using data structure adequate.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Stochastic Ericksen-Leslie Equations'.

assistant: **Innovation**

The objective of the research proposed in this project is to give a sound mathematical description of the noise-induced Fréedericksz transition in Nematic Liquid Crystal (NLC) with general geometry configurations. To this aim we will: 1) solve some important and difficult open mathematical problems related to the stochastic stochasic Ericksen-Leslie Equations (SELEs) which basically describe the dynamics of liquid crystals with stochastic perturbations, and 2) give a rigorous mathematical proof of the noise-induced Fréedericksz transition in NLC. In particular, we will establish the existence and uniqueness solution of the Ginzburg-Landau (GL) approximation of SELEs. By using Large Deviations Principle (LDP) theory and the de Giorgi Gamma-convergence we will prove that the action functional of the SELEs with small spatially converges to the action functional of the SELEs with spatially white noise. We will rigorously justify the probabilistic interpretation of the results in terms of the asymptotics of the mean exit time from a neighbourhood of an attracting stationary solution, a hint to noise-induced Fréedericksz transition. By using again LDP theory will rigorously show that in the presence of small noise there is a positive probability of transition between the attraction domains of the stationary solutions for the deterministic system; this is a rigorous mathematical proof of the noise-induced Freédricks’s transition. We will also prove the existence and uniqueness of an invariant measure which satisfies a LDP. The latter result confirms that in the long run the noise still induces transition between equilibria. Finally, we aim to prove the existence and uniqueness of solution of the SELEs, and if time permits transfer results obtained for the GL approximation of S
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Renewable Energy Communities for a justice-Led And Inclusive energy transforMation'.

assistant: **Innovation**

The European Union (EU) is rapidly transforming its energy landscape with the goal of becoming the world's first climate-neutral economy by 2050. Yet, nearly 10% of EU population struggles with basic energy needs. Renewable Energy Communities (RECs) - citizen-led initiatives for local clean energy production and sharing – are seen as a solution for combating energy poverty and meeting the EU’s climate targets. Does this model ensure that “no one is left behind” in the energy transition, as envisioned by the EU Green Deal? RECLAIM addresses this pressing question by evaluating how effectively RECs engage with vulnerable groups, particularly those at risk of energy poverty. It focuses on rural areas, which have long faced ecological, social and economic fragilities and are now central to the expansion of new energy developments. RECLAIM aims to: 1) identify vulnerabilities to energy poverty within emerging RECs; 2) assess how RECs facilitate participation and benefit-sharing among vulnerable groups and 3) implement community practices to enhance inclusion. RECLAIM introduces a transdisciplinary approach that weaves together advanced quantitative methods - such as multi-dimensional spatial analysis, Earth Observation, and vulnerability assessment - with qualitative tools, including surveys and participatory research. This innovative approach is made possible through collaboration with leading climate science institutes at CMCC, a secondment with the GIScience Laboratory at the University of Padova, a non-academic placement with an innovative energy start-up, and ongoing interactions with a diverse network of stakeholders engaged in local RECs.  As a result, this project creates a unique training environment, boosting the Researcher’s skills and career. Finally, RECLAIM’s m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Commercial feasibility of supramolecular polymers in life sciences and medical technology'.

assistant: **Objectives**

Biomaterials are constructs that can be integrated in the human body to replace or support a biological function. However, their applicability is still limited because they fail to fully integrate with the living body. We have shown that our supramolecular polymer platform has huge potential as biomaterial because its unique properties allow optimal integration with living cells and tissues.Supramolecular polymers are fundamentally different from conventional polymers as their building blocks are not connected permanently but in a reversible fashion using multiple hydrogen bonds. While preserving the properties of conventional polymers, supramolecular polymers can be processed at low temperatures and morphological and mechanical properties can easily be controlled. Due to these properties and the modular approach we introduced, the biomaterial can easily be loaded with the right bioactive agents and can be given the essential properties for optimal integration with living tissues. Moreover, properties such as shape memory and the capacity to self-heal open a whole new window of biomedical applications.We see a broad range of application opportunities like dialysis, innovative sutures and drug delivery where our platform can have a tremendous impact on the life of millions of patients.Right now, we have a clear need to identify the most lucrative and feasible product-market combinations for the technology platform. In addition a detailed plan for further commercialization and product development needs to be developed. This requires extensive research on relevant medical needs, the market, and our IP position. With the current proven technical feasibility of our concept, the ERC Proof of Concept Grant would be perfectly suited to study the commercial feasibility of severa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Complex Analysis and Holomorphic Dynamics' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

The topic of this PhD EuroConference are complex analysis and holomorphic dynamics of one and several complex variables. These are rapidly growing areas which go now through an especially exciting phase, and they are associated to many of the recent most remarkable developments in pure and applied mathematics (recall for instance that some of the last Field Medals have been awarded for significant progress to bring together all the young leading figures in these fields and have them expose and discuss their work, in most cases related to recent advances towards the solutions of the main open problems in their respective areas. Among these topics we find, for example: Julia sets of positive area, local connectivity of the Mandelbrot set, discontinuities on the Hausdorff dimension of Julia sets, holomorphic motions of hyperbolic sets, local behaviour of several complex variables maps around a fixed point, structure of automorphisms of the n-dimensional complex space.All of them will surely be present in the conference age, have already played a significant role in the recent history of these problems. An important objective is also the stimulation of interdisciplinarity. Complex analysis, in several of its various aspects, has been a basic tools in the development of holomorphic dynamics. But, the interaction works in both ways: in the recent years a substantial part of the development of complex analysis has originated in complex dynamics (for instance, quasiconformal mapping in one variable or pluripotential theory in several variables). In this conference, researchers of all these areas will be present and will therefore benefit from each other's knowledge and, probably, different point of view.ftp://ftp.cordis.lu/pub/improving/docs/HPCF-1999-00054-1.pdf
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'A new innovative method for diabetes treatment, the artificial pancreas system' (MedicSen).

assistant: **Concept**

There is a very well-known worldwide problem in the management of chronic diseases and high costs associated to its control resulting in a poor service. Different studies prove how m-health (telemonitoring, apps and sensors) facilitate better understanding and management of the disease. Diabetes is one of the major examples of these facts.MEDICSEN has patented an innovative methodology to personalize the management of chronic diseases that will reduce its socio-economic impact. MEDICSEN is based on continuous monitoring, daily friendly interaction with the patient, and personalized therapies through needle-free drug dispenser.MEDICSEN aim to promote the necessary change in the structure of treatment of chronic diseases, leading the transformation movement towards personalized telemedicine and therefore improving control and reducing spending on such common diseases as cardiovascular, diabetes or obesity. The first case study of technological and commercial application for this general system environment is performed for diabetes but keeping the intention of adapting it to other chronic diseases in the future. Then, MEDICSEN is responsible for modifying the patient glucose curve analysis according to his/her usual behaviour and the value of various parameters (such as temperature, blood pressure or heart rate), thus adjusting the treatment specifically for each individual context and for each moment so the patient can release his/her mind from the dose calculations.The project has a relevant European Dimension. Chronic diseases represent a significant burden on individuals and healthcare systems in the European Union and beyond. The accomplishment of the objectives will result in an EBITDA of 102M€ in five years after put into market MEDICSEN (from € 0.7M in 2017) and an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'BIg Speech data analytics for cONtact centres' (BISON), addressing dissemination and exploitation.

assistant: **Impact**

Contact centers (CC) are an important business for Europe: 35,000 contact centers generate 3.2 Million jobs (~1% of Europe’s active population). A typical CC produces a wealth of multilingual spoken data that is nowadays mined by humans (CC agents  and supervisors) or by rudimentary technical means.BISON consortium plans to bring significant innovations in three areas: (1) basic speech data mining technologies (systems quickly adaptable to new languages, domains and CC campaigns), (2) business outcome mining from speech (translated into improvement of CCs’ Key Performance Indicators) and (3) CC support systems integrating both speech and business outcome mining in user-friendly way.The project will produce two prototypes: smallBison (end of the 1st year) will be a functioning system for real, though limited, deployment and user feedback collection. bigBison (end of the project) will include full range of capabilities and be fully integrated with CC hardware and software infrastructure. Generation of business outputs will be demonstrated on real data.Business indicators and values for the market were instrumental for the definition of the project and will be crucial for project execution.BISON consortium is composed of eight players with complementary skills. Two end users running large CC operations (EBOS, Atento) are generating user requirements and are ready to deploy the prototypes immediately in real scenarios. Phonexia (the coordinator), Brno University of Technology and Telefónica I+D are experts in speech data mining - from R&D, data processing to developing products placed on the market. Telefónica Móviles is an expert in business outcome mining and MyForce is a skilled Contact Center hardware and software integrator. CC data involve a number of legal issues, th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Generateur programmable de signaux intracellulaires pour la culture in-vitro d'ovocytes et d'embryons de mammifères domestiques'.

assistant: **Innovation**

The future importance of domestic species is expected to arise especially for their increasing commercial use in the fields of biotechnology and human health The large numbers of cheap embryos are integral to the production of pharmaceutical proteins, xenografting and as models for human disease. The technology currently exists and in-vitro procedures have been most heavily useful in commercial companies involved in animal breeding and biotechnology. Whilst some of the European commercial entreprises have survived, others have f largely because of inadequacies in the current in-vitro techniques associated with embryo production. The objective of this preparatory award is to radically improve the efficiency in-vitro of oocyte growth maturation and early embryonic development by developing a new process which is able to manipulate the rhythm of oscillar parameters (intracellular calcium ions increase, second messengers) by using a intracelluar signal generator (Puls-Ions) with frequency and amplitude modulator (Ozil & Swann, 1995 J. Physiol, 483). Two set-up which applies our process have been constructed an are in operation. Preliminary results have demonstrated the suitability of our process. It involves replacing the traditional and passive in-vitro culture methods with a dynamic system able to generates a large range of intracellular signals in the oocyte and/or embryo during the various phases of the reproduction process oocyte growth, maturation, fertilization and development which imitate naturally occurring conditions (calcium ions is a critical regulator of many cellular processes and intracelluar calcium changes occur transiently during th cell cycle). Links have been established among four partners; with a French company (Sanofi), with an Italian private sector
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Developing a Fibrosis Targeting and Tissue Reparative (FiTTeR) Therapy for the Infarcted Myocardium via an Injectable Functionalized Extracellular Matrix Hydrogel' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

As a Marie Skłodowska-Curie Fellow, I will develop, characterize, and determine the efficacy of a biomaterial platform to target pathologic fibrosis and promote tissue repair following myocardial infarction (MI). I have an ideal background and will perform well in this project based on my expertise in extracellular matrix (ECM) derived biomaterials, characterizing the immune response to biomaterials, and evaluating in vivo outcomes. The proposed system will consist of a protein fragment tethered to an injectable hydrogel. The hydrogel carrier will be composed of ECM, which has been shown to facilitate tissue repair processes by local modulation of immune cell phenotype . The cryptic protein fragment, recently isolated and recombinantly produced by the Stevens Group , has gained attention for its ability to regulate the onset of fibrosis by interfacing with cells to abrogate the release of matrix metalloproteinases (MMPs). No therapies currently exist to prevent or mitigate fibrosis. Developing a sophisticated delivery system for a cryptic protein fragment will enable the broad potential of targeting pathologic fibrosis to be realized. This system will be advantageous in simultaneously providing localized delivery, combined immunomodulatory and regulatory properties of the ECM and recombinant protein fragment, and sustained release of the protein fragment during degradation of the ECM hydrogel. The combination of my expertise (in ECM hydrogels, characterizing the host response to biomaterials, and translating technologies) and Prof Molly Stevens’s supervision and world-class interdisciplinary biomaterials-focused group, the 2014 Research Group of the Year (European Life Science Awards), at Imperial College London (ICL), together make this project ideally suited for succe