RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'VIRTUAL TECHNOLOGICAL EXPERIMENT IN WELDING' (VITEWE) targeting Fourth Framework.

assistant: **Abstract**

The objective of VITEWE is to develop a method that allows the optimisation of welding parameters using a virtual reality procedure before the execution of the actual welding. This method will be based on sophisticated mathematical models, advanced methods of numerical simulations, a specially created database concerning welding technologies and equipment, and an advanced virtual reality graphical representation of the welding.The virtual welding experiment will be organised as follows:the user will choose the basic welding technology to be used (laser, plasma-arc, electron beam, etc.), the required set up, materials to be welded, and the welding parameters (speed, power, energy beam diameter);based on the chosen welding conditions, a virtual experiment will be executed numerically; the evolution of the welding process will be represented by the dynamics of: temperature fields, molten pool shape, keyhole formation, etc.;the whole virtual experiment will be analysed by a virtual diagnostic equipment such as pyrometers, acoustic emission, thermocouples, spectrometers, etc.;the result of the virtual experiment will be represented by a 3D image of the obtained welded seam and its cross-sections;the results of the virtual welding will be analysed and necessary modifications of the parameters will take place before the next virtual welding.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'The emergence of “actin stars” for epithelium coordination and tissue patterning', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Faithful epithelial morphogenesis is crucial during development and tissue homeostasis. The dynamic intestinal epithelium is an appropriate model to study this field of research. Constant regeneration of epithelium is one of the main characteristics of intestinal homeostasis mediated by finely controlled balance between intestinal stem cell proliferation and differentiation. Therefore, it is instrumental to study mechanisms controlling intestinal organization to understand tissue homeostasis and function.Actin cytoskeleton plays an important role in regulating epithelial morphogenesis. Recently, by using 2D and 3D intestinal organoids, the host lab has discovered a new unique multicellular star-shaped actin assembly, termed actin stars (AcSs) located in the basal domain of differentiated epithelium. This network is characterized by 6-branched star-shaped actin clusters covering the entire basal surface, with AcS node at the centroid of the cell and each branch of the star orthoradially connects the plasma membrane, and directly mirrors a corresponding branch from a neighbouring cell. They confirmed such actin structures in vivo in mouse small intestine. The AcSs may represent a large-scale inter-connecting meshwork in the differentiated epithelial domain. Considering the novelty of these results, we would like to investigate the interplay between large-scale AcS networks and tissue morphogenesis. Here we aim to dissect the organization of AcS network, determine the processes leading to their formation, and understand the importance of AcSs for individual cells as well as epithelial assemblies. For that we will carry out a multi-disciplinary approach, combining the use of high-resolution imaging, optogenetics, genomics coupled to physical modelling. We anticipate that ou
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Influence of microflora on heavy metal cycles and water quality' under Fifth Framework.

assistant: **Concept**

The bio-geo-interaction group is a main partner in a nationally funded research programme using the specific characteristics of the former uranium mining site (Wismut area) to investigate transport mechanisms between geo-, hydro- and biosphere. However, the ecology of the habitat is not investigated and this is a point which needs immediate attention if not molecular mechanisms are to be studied in systems that have no relevance in nature. This microbiological project at the interface of geosciences and biology has to be initiated with new competence from abroad which can not be generated from within the bio-geo-interaction group alone. Therefore, the impact of the proposed research is rated extremely valuable for the scientific competitiveness of the geo-bio-interaction research in the Jena region and will help us to attract fututre funding from national and international sources.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Rotaxane-Oligonucleotides: Stimuli-Responsive Mechanically Interlocked Architectures to Control Oligonucleotide Activity and Gene Transcription' in the context of a Horizon 2020 call.

assistant: **Objectives**

Recently, DNA-mimics have been developed in which a natural phosphate unit linking the DNA bases is replaced with a non-natural triazole. This DNA-mimic behaves identically to natural DNA, presenting an opportunity I will exploit during this Fellowship: my mentor, Prof Goldup, has developed chemistry that wraps a ring-shaped molecule (macrocycle) around such triazole links to produce interlocked molecules called rotaxanes. These molecules are perhaps most famous as components of molecular machines, culminating in the 2016 Nobel Prize for chemistry part-awarded to Stoddart and Sauvage, but the mechanical bond also offers opportunities to control the chemistry of the interlocked components.Combining these approaches, I will create interlocked rotaxane-DNAs to study how threading the macrocycle onto DNA affects the biological function of the nucleic acid. During this Fellowship I will develop the first generation of rotaxane-oligonucleotides, study their properties and utilize the mechanical bond to regulate their biological activity. These interlocked oligonucleotides will be demonstrated as versatile new tools for chemical biology through examples of controlled gene expression and therapeutic siRNA applications.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'DNA, Environment, Mineral Association: Reaction Kinetics'.

assistant: **Concept**

Environmental DNA (eDNA) is trace amounts of DNA released by organisms into water and sediments. It has recently attracted a lot of attention as it can be a valuable tool for detecting present and past organisms without the need to directly sample them. However, biotic and abiotic decay has severe effects on DNA survival. The adsorption of DNA to mineral surfaces in sediments as well as saline conditions have been shown to protect DNA molecules and decrease the DNA decay rate. Understanding which minerals and environmental conditions provide the best preservation of adsorbed DNA can thus allow us to: a) target such environments for paleoecological and palaeogenetic studies; b) serve as a quantitative tool for assessing DNA migration, i.e. is the recovered eDNA autochthonous?; and c) significantly advance eDNA extraction and analysis protocols by targeting and extracting eDNA from specific minerals.Currently, we only have a qualitative understanding of the DNA-mineral adsorption/desorption at the bulk level and we have no quantitative insight into the DNA-mineral interactions and solution conditions that enhance DNA survival, nor the combined impact on DNA longevity in natural environments. With DENMARK I will (1) assess DNA-mineral associations and correlate with eDNA preservation state in sediments from terrestrial, freshwater and marine settings. Additionally, for a range of sedimentary minerals and a range of environmentally relevant solution compositions I will: (2) quantify the Gibbs free energy (ΔGbu) and kinetic bond parameters of in vitro DNA-mineral interactions; and (3) examine the nature, fraction and stability of interacting bonds of in vitro DNA-mineral associations at the bulk level. (4) Finally, I will link the sediment data to the in vitro single bond an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Modernisation of Agriculture through more efficient and effective Agricultural Knowledge and Innovation Systems'.

assistant: **Innovation**

modernAKIS aims to improve AKIS actors’ capacities to leverage individual, organizational and systemic resources needed for the transformation towards more coherent, effective and efficient AKIS systems and the transition to a more sustainable management and use of natural resources in farming and forestry.To this end it will build and foster a European network of at least 1.000 key AKIS actors, including AKIS coordination bodies, from all EU MS, who will act as linchpins in the transformation of the AKIS systems towards a more effective governance and the modernization of the European agri-food sector. The project will also build the capacities of these key AKIS actors towards systems understanding and engagement, enabling them to enact long-term system changes that will improve the AKIS. In addition, it will set up at least 1 Community of Practice in each Member State, enabling thus participants to act as vectors of change in their communities. In addition, modernAKIS will provide a comprehensive digital catalogue with new know-how, and at least 80 tools and methods supporting key AKIS actors to improve the knowledge flows and develop a well-functioning AKIS in line with relevant policy objectives, e.g the Green Deal, Farm2Fork, SDGs.


**Keywords:** Agricultural Knowledge and Innovation Systems, Modernization of Agriculture
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Clean water with clean energy. Drinking water provision in remote regions with decentralised solar power supply' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

The main objectives are as follows:* To get an overview on the situation of drinking water provision in rural regions of Latin America.* To get an overview on the one hand on water treatment technologies applied in rural regions of Latin America and on the other hand on commercially available devices for decentralised drinking water purification.* To make suggestions for sustainable water management in rural villages in Latin America.* To set up design guidelines for decentralised drinking water purification systems powered by solar energy.* To couple treatment devices for decentralised drinking water provision to photovoltaic systems and to develop by this way stand-alone water purification systems.* To install two water purification systems powered by solar photovoltaics in two pilot-villages, one in the province of San Juan, Argentina, and the other one in the State of Mexico, Mexico.* To disseminate the experience gained in the project.Expected OutcomeThe work carried out in this project together with the World Health Organisation WHO as external partner should provide suggestions how to improve drinking water provision and therefore how to improve living conditions and health of people settling in rural areas of Latin America. Recommendations for design, implementation and operation of solar powered water purification systems will help to achieve this goal.The key activities envisaged are:* Assessment of situation of water pollution, needs of water and needs of drinking water purification together with the legal background in rural regions of Latin America.* Isolation of typical problems regarding the water provision in rural Latin America.* Elaboration of a catalogue of applicable purification technologies and available devices.* Laboratory- and field tests of pro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Deeptech startup support programme to facilitate ventures thriving in the European Widening area'.

assistant: **Innovation**

European startups face barriers when scaling due to the cultural, legal and economic fragmentation of the market. While the EU demonstrates high performance in “the lab”, this does not translate proportionally into thriving commercial ventures. For deeptech startups, the key challenge is the lengthy time needed to reach a maturity level adequate for adoption, making investing risky. In the case of Widening Countries, commercialization of deeptech is even more challenging.The EC has made a substantial effort to support deeptech with initiatives aiming to invest in and connect entrepreneurs at a pan-European scale (EIC Accelerator and the Startup Europe initiative). VENTURES THRIVE inherits the spirit of these initiatives, concretely building on three waves of Startup Europe with a novel approach targeted at deeptech startups in Widening Area countries. This unique open innovation startup programme will provide up to €100K (cash and vouchers) each to a total of 32 startups. Along with equity-free funding, the core programme offers value-add services aimed at: fostering access to markets via corporate challenges, improved investment readiness, and greater visibility, investment and networking opportunities. The project consortium and external associates comprise venture builders, event organisers, VC & Angel Investors, corporates and expert mentors. Overall, the startups are expected to unlock +€18M via investment, grants and corporate procurement.The secret ingredient is the consortium and their extensive networks. ACCELER8 (Malta) is a venture builder commercialising top-level scientific innovations. ANTHOLOGY VENTURES (Bulgaria) is a venture studio, incubating early-stage teams and business angels. WOLVES SUMMIT (Poland), the major event for startups in the CEE region,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Femtocell-based netwoRk Enhancement by intErference managEment and coorDination of infOrmation for seaMless connectivity' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Currently, femtocells and macrocells are seen as isolated networks, competing for the resources available in the common spectrum band, at the cost of injecting interference to the whole system. FREEDOM project will face key technical and industrial concerns about the foreseen mid-term massive deployment of femtocells by adopting a new approach based on cooperative/coordination paradigms, enabled by the limited ISP backhaul link. The project will not disregard the approach of isolated networks because it is met when there is not enough backhaul link connecting the femtocells and macrocell. In order to guarantee a strong focus and efficiency, FREEDOM will focus on: advanced interference-aware cooperative PHY techniques; improvement of the control plane procedures for seamless connectivity and system-level and hardware feasibility evaluation of the proposed femto-based network architecture.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Mixed-Integer Nonlinear Optimization'.

assistant: **Concept**

Complex decision making in enterprises should involve mathematical optimization methods, because a “best choice” has to be made out of a huge number of feasible options. A mathematical description of such decision processes typically involves both “continuous” and “discrete” decisions. If the latter are present, the customary modelling approach is to use integer variables, which are also used to represent all possible nonlinearities, so that the remaining part of the model is linear. This leads to  Mixed-Integer Linear Optimization (MILO) problems, which can be handled nowadays by many packages, but are often very difficult to solve.Difficulty of MILO problems is often due to the fact that objective functions or constraints that are structurally nonlinear (e.g., quadratic) are linearized by introducing new integer variables. In many cases, it was observed that this is not the best way to proceed, as facing the nonlinearity directly without the new variables leads to much better results. Algorithmic technology for the resulting Mixed-Integer Nonlinear Optimization (MINO) problems is still at its early stage.The present situation is that enterprises facing a MINO problem generally give up due to the lack of efficient solvers, or try to convert it to a MILO one often too hard to be solved in practice. On the other hand, in the academia there is now an increasing expertise in MINO, which is however hardly exported outside due to the lack of interaction with the industrial world. It is the purpose of this project to help satisfy the increasing demand for highly qualified researchers receiving, at the same time, a state-of-the-art scientific training from the academia and hands-on experience with real-world applications from the industry.The researchers formed within this pro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Temporal Adaptation and anticipation Mechanisms in Human-Robot interaction' (TeAMH-Robot) under Horizon 2020.

assistant: **Objectives**

In the near future, the advent of robots will change the role that artificial agents play in our life, as the interaction with them will not be limited to specialized and well-structured work environments. When interacting with artificial agents, humans often occur into the Out of The Loop phenomenon (OOTL), that is a difficulty to predict and prevent failures, probably due to a lack of transparency in artificial agents actions. The overarching aim of TeAMH-Robot is to develop a model of Human-Robot Interaction (HRI) that will prevent the OOTL phenomenon when interacting with robots. To this end, TeAMH-Robot will use a novel approach to develop efficient HRI that combines cognitive neuroscience methods with real-time interactive tasks with a humanoid robot. Firstly, TeAMH-Robot will aim to understand how temporal adaptation and anticipation mechanisms allow humans to “stay in the loop” when mistakes occur. Then, TeAMH-Robot will use this knowledge to develop a human-inspired module for humanoid robots that ensure real-time coordination. Finally, TeAMH-Robot will test the efficiency of human-inspired behaviour in reducing the impact of the OOTL phenomenon. The outgoing phase will be hosted by the Western Sydney University (Australia), where the ER will (i) identify and (ii) model temporal adaptation and anticipation mechanisms that allow humans to predict, prevent and recover mistakes. The return phase will be hosted by the Italian Institute of Technology (Italy), where the ER will (iii) develop a module for humanoid robots that ensure real-time coordination and (iv) test its efficiency in reducing the OOTL by means of the acquired neurocognitive methods. TeAMH-Robot will increase ER’s expertise on social cognitive mechanisms and allow her to start her independency. More