RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Code of practice for the determination of uncertainties in mechanical tests on metallic materials' (UNCERT) under Fourth Framework.

assistant: **Objectives**

Mechanical testing labs (tensile, impact, toughness, fatigue, crack growth ...) are increasingly required to include in their test reports the uncertainties affecting the data they have measured. However, the possibility to indicate the uncertainties for the measured parameters is often made difficult by a number of aspects which are peculiar to the mechanical tests:- the sample may be destroyed as a consequence of the measurement, so that exact test repetition is impossible,- several comparison tests have to be performed to get appropriate statistical amount of data (in order to deal with material homogeneity aspects and inherent test measure scatter),- reference data (from Certified Reference Materials, CRM) rarely exist.Detailed procedures for the determination of uncertainties in all measured test parameters on metallic materials do not exist.The aim of UNCERT project is to formulate the procedures for uncertainty evaluation in mechanical tests on metals (code of practice). The procedures will be defined as the best (in terms of cost/benefit criterion) among several existing options, namely theoretical combinations of uncertainties in directly measured quantities derived from instrumentation tolerances, direct comparisons with CRM's, and possible use of statistical methods (e.g. advanced methods based on fuzzy analysis, pattern recognitions ..).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Degradation of Neutrophil Extracellular Traps and its impact on thrombolysis'.

assistant: **Concept**

Thrombosis is a major cause of morbidity and mortality emphasizing the need for new antithrombotic therapies.Recently, a novel pro-thrombotic mechanism was uncovered:  Neutrophil Extracellular Traps (NETs).  Neutrophils, the chief cells of the innate immunity, release DNA fibers during thrombosis.  These extracellular DNA filaments form web-like structures known as NETs, which provide a scaffold and stimulus for thrombus formation in vitro and in vivo.  Moreover, NETs are associated with thrombosis in patients underlining that NETs are a new therapeutic target.In order to identify therapies against NETs, we propose to address the unanswered question: how are NETs neutralized in vivo?  It is known that extracellular DNA is digested by cooperative action of DNase1 and DNase1-like 3 (DNase1l3) in vitro.  DNase1 and DNase1l3 are the only DNases in plasma and we hypothesize that they degrade NETs within thrombi.  Furthermore, we speculate that degradation of NETs causes thrombus destabilization and facilitates thrombus resolution.  To test the hypothesis, we will employ DNase1- and DNase1l3-deficient mice, infusions of recombinant murine DNase1 and DNase1l3 as well as infusions of DNase1 antibodies.  To address NET degradation specifically, we will use genetically engineered mice, which cannot form NETs.  Using these tools, we propose to investigate the role of plasma DNases in NET-degradation in murine models of arterial and venous thrombosis.If our hypothesis is correct, the proposed experiments will reveal the mechanism of NET-degradation in vivo and identify plasma DNases as drug candidates for antithrombotic therapy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Enhancing Liveable Cities with Smart Public Space Management and Sustainable Mobility for climate neutrality in urban areas: the URBAN-FLOW Approach' under Horizon Europe.

assistant: **Concept**

URBAN-FLOW is a groundbreaking initiative designed to reshape urban spaces into sustainable, climate-neutral, and resilient environments. The project addresses key urban challenges such as limited public space, inefficient mobility and land use planning, suburban connectivity gaps, fragmented energy and mobility systems, and the need for inclusive, liveable urban areas. By integrating Local Digital Twins (LDTs) and Mobility Data Spaces (MDS), URBAN-FLOW enhances data-driven decision-making, enabling dynamic space management and participatory urban regeneration towards climate-neutral mobility, integrated energy, and resilient design.The project is demonstrated in three Lead Cities: Valencia (Spain), Florence (Italy), and Tampere (Finland), where innovative urban solutions will be tested. These solutions include dynamic curb-side management, multimodal transport optimization, and green infrastructure integration. The project also involves three Replicant Cities: Edinburgh (United Kingdom), Brussels (Belgium), and Pilsen (Czech Republic), ensuring the scalability and adaptability of the proposed measures across diverse urban contexts.URBAN-FLOW employs a systemic co-creation approach through City Living Labs (CLLs), engaging policymakers, citizens, and businesses in collaborative urban transformation. The project aligns with the European Green Deal and the Mission 100 Climate-Neutral Cities, driving policy-driven replication across European cities. By combining advanced digital tools, participatory governance, and climate resilience strategies, URBAN-FLOW seeks to create urban environments that enhance accessibility, reduce greenhouse gas emissions, and improve the overall quality of life for residents. To maximise its footprint and its results uptake, the project leverag
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Scaling Methods for Discrete and Continuous Optimization' (ScaleOpt).

assistant: **Concept**

One of the most important open questions in optimization is to find a strongly polynomial algorithm for linear programming. The proposed project aims to tackle this problem by combining novel techniques from two different domains: discrete optimization and continuous optimization. We expect to contribute to exciting recent developments on the interface of these two fields. We use and develop new variants of the classical scaling technique. From the discrete optimization side, recent work of the PI on generalized flows extends classical network flow theory and opens up new domains for strongly polynomial computability beyond integer constraint matrices. We will apply this novel scaling technique to obtain strongly polynomial algorithms for broad classes of linear programs.From the continuous optimization side, we aim to build the theory of geometric rescaling algorithms for linear and convex optimization. This approach combines first-order methods with geometric rescaling techniques to obtain a new family of polynomial-time algorithms. We expect to devise variants efficient in theory and in practice, which we will use in a wide range of applications.Our discrete and continuous techniques will have important applications in submodular function minimization. We will develop new, efficient algorithms for the general problem as well as for specific applications in areas such as machine learning and computer vision.In summary, the project will develop novel approaches for some of the most fundamental optimization problems. It will change the landscape of strongly polynomial computability, and make substantial progress towards finding a strongly polynomial algorithm for linear programming.


**Keywords:** linear programming, strongly polynomial algorithms, network optimization
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Embryonic stem cell origin of the adipose tissue macrophages' (ESATM), addressing dissemination and exploitation.

assistant: **Impact**

Today insulin resistance (IR) is reaching pandemic proportions and it is predicted to emerge a leading worldwide morbidity by 2030. Immune cells, including the so-called adipose tissue macrophages (ATMs) have key roles in the development of this disease. Pharmacological intervention to shape ATM differentiation and function may be a straightforward approach to prevent or combat IR. However the stem cell origin of ATMs is still unclear, which blocks the development of such prevention or treatment strategies. Recent reports show that some specific sets of macrophages develop from embryonic hematopoietic stem cells (eHSCs) and not from the bone marrow as it was postulated before. Our preliminary studies raise the possibility that eHSCs are present in the mouse and the human adipose tissue and these stem cells replenish the ATMs in adulthood. The major scientific objectives of this project are to (a) address the critical question whether ATMs are derived from eHSCs, and (b) define whether the eHSC-derived ATMs can cause IR. These are novel and non-conventional ideas on the determination of IR and are challenging the current wisdom on ATM origin. The deliverables of this project may open a new path to alleviate or prevent IR through eHSCs.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Combined Model-based Analysis and Testing of Embedded Systems' to be submitted under Seventh Framework.

assistant: **Abstract**

One of the most important strategic sectors in which Europe is developing, integrating and delivering high-quality products is the transportation domain. Here, high-class safety-related products as e.g. airplanes, cars and trains have a huge market impact. More and more of the market value of these vehicles is gained by embedded systems inside these products, and the number and importance of these embedded systems is steadily growing.One of the most important enablers to assure the quality of embedded systems is the application of powerful validation and verification (V&V) technologies accompanying the embedded systems development process. Unfortunately, the V&V technologies already in industrial use are still too expensive while often not effective enough. MBAT will provide European industry with a new leading-edge V&V technology in form of a Reference Technology Platform (MBAT RTP) that will enable the production of high-quality and safe embedded systems at reduced cost in terms of time and money. This will be made possible by a new and very promising approach in which model-based testing technologies will be combined with static analysis techniques. Besides this combination, a further new approach is to use (and re-use) specially designed test & analysis models as basis for model-based V&V. This advanced model-based V&V technology will lead to a more effective and at the same time cost-reducing approach compared to traditional ones. In addition, MBAT RTP will be connected to other ARTEMIS RTPs to extend existing platforms. Developed by industrial key players (large companies and SMEs) in this domain and supported by leading research partners, the MBAT RTP will be of high value for the European industry, providing very effective means to assure utmost quality embedded
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'My Impact Portal' to be submitted under Horizon 2020.

assistant: **Abstract**

The My Impact Portal offered by C-Change is a a portfolio management tool for corporate teams to capture, share, and accelerate all company-wide Corporate Social Responsibility (CSR), sustainability, and global impact initiatives.Its overall goal is to address the issues of businesses struggling with purpose-driven management, a failing market system and lack of transparency for CSR. With this portal, businesses are better provided to play a transformative role in global society and deliver on the UN-SDG and Paris Agreement mandates.My Impact Portal is based on a paradigm shift from fragmented social impact data towards shared network functionalities that can be applied to any Sustainable Development Goal (SDG). The portal is an easy to use scalable LinkedIn like tool that brings all scattered inter-company data and activities to one intranet portal, and connects this data and activities to external open, public, private, NGO and other SDG-related platforms, based on a set of objective metrics, verification methods, and taxonomy.The objective for this SMEInst Phase 1 feasibility study is to develop a roll-out and business plan to launch the corporate B2B proposition in Europe and beyond.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'IONGELS: FROM NEW  CHEMISTRY TOWARD EMERGING APPLICATIONS' (IONBIKE), addressing dissemination and exploitation.

assistant: **Impact**

IONBIKE proposes a research and staff exchange program will promote international and intersectorial collatorations in the topic of “Innovative Iongels for Bioelectronics”. The european consortium is formed by 4 European beneficiaries from which three are academic institutions such as University of the Basque Country (Spain), University of Cambridge (UK) and University of Bordeaux (France) and a high-tech company in bioelectronics named Panaxium from France and 5 institutions from third countries such as CONICET (Argentina), UCIMED (Costa Rica), Deakin University (Australia), KAUST (Saudi Arabia) and Georgia Tech (USA). The project proposes an intensive research and networking program between the european and non-european institutions in the area of new materials for bioelectronics. The scientific project tries to combine in a synergic manner the unique technical expertises of the different nodes. World pioneers in the areas of ionic liquids, iongels, (semi)conducting polymers, advanced materials characterization and (bio)electronic devices will work together towards a common goal. The project will pursue the development of devices for health and fitness monitoring such as long-lasting electrodes for electrophysilogical recordings for brain, heart and muscular activity or new all-solid organic electrochemical transitors. The exchange of Know-How will promotes the development of excellence science and innovation and helps to turn creative ideas into innovative products which will be exploited by the participating company PANAXIUM.


**Keywords:** Biopolymers, Iongels, Electrochemistry,  Bioelectronics, Batteries
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Innovative Re-Design and Validation of Complex Airframe Structural Components Formed by Additive Manufacturing for Weight and Cost Reduction' (AddMan) under Horizon 2020.

assistant: **Objectives**

Additive manufacturing (AM) is a technology by which physical objects can be built directly from 3D Computer Aided Design (CAD) data, and is widely acknowledged as an enabler for revolutionizing the manufacturing landscape. It replaces traditional production methods like casting and machining, and enables essentially arbitrary geometric shapes to be produced. Although significant progress has been made on AM hardware development, there is a lack of efforts regarding material characterization, design tools and methods to efficiently bring AM to practical use in the aeronautical area. In particular, Topology Optimization (TO) – a finite element based design method – is an unusually evident and potentially fruitful technique for designing AM structures. However, the mechanical properties of AM components differ substantially from the properties of the same components produced by conventional methods, and AM components can have complex shapes, such as grid-like structures, that cannot be achieved by using conventional production methods. Therefore, the AddMan project deals with:• Material characterization by establishing fatigue properties and geometry dependent material behavior as well as AM specific build requirements• Development of novel TO methods, as well as CAE methods for metal AM which make use of the material properties generated in AddMan• Development of Design for AM-guidelines that are implemented in an automated knowledge based engineering framework including connection between TO and flexible parametric CAD models, to enable holistic product optimization and• Development of a cost effective post-processing strategy for AM components in order to increase fatigue performance.These developments build towards the overall aim of enabling aerospace industry to eff
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'LEMON Less Energy More OpportuNities' in the context of a Horizon 2020 call.

assistant: **Objectives**

LEMON ""Less Energy More OpportuNities"" focusses on energy investments in the Social Housing sector and involves 2 Housing Company of Emilia Romagna Region ACER Reggio Emilia and ACER Parma,  launching 15,29 M€ of energy investments in 622 private and public social housing dwellings.The project will develop innovative, bankable and aggregated sustainable energy investment scheme based on the following aspects:-  LEMON will be a pilot project for the Emilia Romagna Region Social Housing Programme, creating a new financing model for energy retrofit interventions and developing a EPC model contracts that will mobilize 15,29 million Euros of investments in social housing buildings energy retrofitting, in order to reduce the buildings energy demand. LEMON will support the investments combining different financing instruments available at National and Regional level (ERDF funds, National financing, National incentive “Conto termico” and loans) and in particularly it will charge part of the investment on the rents according to the reduced energy costs for the tenants.- LEMON will develop the Energy Performance Tenancy Agreement (EPTA). The contract between the tenants and the ACERs will ensure that a portion of the investments covered by ACER Reggio Emilia and ACER Parma with a loan is charged on the rents for as long as the loan is repaid, leveraging on the savings produced by the retrofit interventions.. The replication of the project will be based on a wide dissemination and capacity building strategy among the social housing companies at regional and national level, and also among other sectors (City councils, Provinces, Regional, public authorities, Groups that represent e.g. Local Government Association, National public authorities, Organisations working in the field of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Gaining sage on the Epoetins' saga: assessing long term risks and advancing towards better Epoetin driven treatment modalities' under Seventh Framework.

assistant: **Concept**

EpoCan aims to develop and implement a comprehensive interdisciplinary strategy to assess the long-term risks of erythropoietin (EPO) and its derivatives (epoetins) on tumour growth progression and thromboembolic events in cancer patients, cardiovascular events, and the development of cancer in chronic kidney disease. Approximately 400,000 patients across Europe receive epoetins treatment each year. Recent meta-analysis data have raised concerns over increased mortality in some patient groups. Hence the urgent need to evaluate the risk-benefit ratio of epoetin treatment and its potential long-term effects.EpoCan brings together a multidisciplinary consortium of 12 world leading academic, industrial and medical partners, with long-standing, complementary expertise in haemostasis, oncology and EPO biology. EpoCan aims to (1) Identify, detect and measure possible long-term hazards of epoetin treatment; (2) Develop novel prognostic tools and new complementary therapeutic reagents: (3) Evaluate the risk-benefit ratio to pave the way for new safety and efficacy criteria.EpoCan will: (a) Utilize a wide array of cellular models to thoroughly analyze EPO/EPO receptor(EPO-R)interaction and signalling, to define the relationship between EPO-R expression in tumour samples and the clinical outcome in cancer patients; (b) Establish and test new, personalized, predictive tools (EPO-R peptide antagonists, novel specific anti-EPO-R monoclonal antibodies, thromboembolic tests); (c) Create new murine models as hosts for tumour implantation subjected to EPO and derivatives established above; (d) Screen and analyze clinical databases; (e) Define models to predict hazardous versus safe/beneficial roles of epoetins in the treatment of cancer and kidney failure associated anaemia. Data obtaine