RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'High Arctic Polynyas in a Changing Climate' to be submitted under Horizon 2020.

assistant: **Abstract**

The Arctic is undergoing a profound transformation. The striking increase in observed Greenland Ice Sheet melt and sea-ice retreat are two symptoms of the multiple impacts of climate change at high latitudes. In the sea-ice covered oceans surrounding northern Greenland however, large areas of year-round open water, termed polynyas, have been present since historical times. Located at two major Arctic-Atlantic gateways, these biological productivity hotspots support not only large mammals and birds but are a vital natural and cultural resource for indigenous Arctic communities. Polynyas also act as a potentially significant carbon sink. Three large polynyas recurrently form around northern Greenland. Paleoceanographic reconstructions of the largest, the North Water Polynya, indicate that the polynya and its associated ecosystem are extremely sensitive to rapid climatic fluctuations during the Holocene. Taking advantage of new, readily available marine sediment cores, I propose to reconstruct, for the first time, ocean circulation and sea-ice dynamics at the two main polynyas in the Greenland Sea (North East Water and Sirius Water). This action will target key climatic intervals in the early (Holocene Climatic Optimum) and late (Little Ice Age, Medieval Warm Period) Holocene and provide direct input to a fully-coupled earth system model to evaluate past and, more vitally, predict future dynamics under different greenhouse gas concentration pathways defined by the IPCC. This action provides a unique opportunity for me to learn a new proxy for Arctic paleoclimate reconstructions, skills in the applicability of paleo-data to modelling and a number of essential transferable skills such as scientific writing and mentorship, coupled with an extensive new network of expert colla
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Demonstration of the economic feasibility of a wave-powered desalination system' (W2O).

assistant: **Innovation**

Over 1 billion people suffer from the effects of water scarcity with the vast majority being poor residents of developing countries. Desalting seawater is an excellent potential solution but traditional reverse osmosis (R/O) desalination systems require a connection to a strong electrical grid. However, because developing countries typically lack sufficient electrical grid capacity and cannot afford the capital or time required to build and deploy traditional R/O systems, RML is proposing an innovative solution to this problem - the world’s first wave-driven desalination system (called Wave2O™) that can be deployed quickly, operate completely “off-grid” and supply large quantities of fresh water at competitive cost. As a medium-scale, grid-independent, renewable energy driven water production system, we believe Wave2O™ will have wide-ranging utility in developing countries and island nations outside Europe. Inside Europe, potential markets include the overseas Departments and Territories linked to EU member states (e.g. Canary Islands, New Caledonia, etc.). RML has already been active in several countries and has obtained commitments for pilot-scale Wave2O™ plants in Cape Verde, South Africa and Mauritius. We believe Cape Verde represents the shortest path to commercialization. The pilot location has been already secured and the site assessment studies are expected to start in Q3 2017 financed by the African Development Bank through a $1.0M SEFA (Sustainable Energy Fund for Africa) grant. The purpose of the W2O project will be to build upon the SEFA-funded site assessment studies to determine the economic feasibility of Wave2O™ in Cape Verde and to pave the way for the commercial pilot in 2019. The eventual global deployment of Wave2O™ plants will help create a very com
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'BIOlogical SignaTures of AnhydrobioSIS  via comparative transcriptomics on different evolutionary lineages within tardigrades' (BIOSTASIS).

assistant: **Innovation**

The current proposal revolves around the dehydration induced state, anhydrobiosis - a survival strategy found among a range of life-forms in face of severe desiccation. Anhydrobiosis is defined by a reversible shut-down of metabolism (biostasis) and it seems to involve adaptations at all levels of organismic organization. The current proposal uses tardigrades as a model to gain novel insight into molecular signatures underlying this unique biological phenomenon. Several molecules have been implicated in the anhydrobiotic mechanism; however, so far studies have been returning contradictory results with respect to the differential expression of genes in pre- and post-anhydrobiotic phases. Interestingly, our preliminary, unpublished data from Møbjerg lab suggest that there could be lineage specific strategies to anhydrobiosis.  Consequently, I will use transcriptome sequencing (RNAseq) and ddPCR to reveal key-player genes and characterize functional pathways involved in i) different stages of anhydrobiosis of single tardigrade species and ii) between different evolutionary lineages within the phylum. The mentioned methods constitute the most important training element of my project. The overall goal of the proposal is to determine potential gene expression signatures for anhydrobiosis establishing a transcription profile that is i) characteristic of a particular physiological state and ii) that could possibly reflect the phylogenetic position of a taxon. My previous extensive experience on phylogenetic and molecular dating methods will, in this respect, be utilized to estimate the chronology of the possible diversification of anhydrobiosis within evolutionary lineages. My research will be conducted at the Møbjerg lab, which represents one of the world’s leading groups in t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Yeast Systems Biology Network' in the context of a Sixth Framework call.

assistant: **Objectives**

Systems Biology is an emerging field expected to have a major impact on the future of biological and medical research. It aims at systems-level understanding of biological processes by employing mathematical analyses and computational tools to integrate the information content obtained in experimental biology. The Yeast Systems Biology Network (YSBN) proposes the yeast Saccharomyces cerevisiae as a model system to develop the field and to advance our understanding of the rules and principles of the dynamic operation of cellular systems.YSBN will serve to integrate activities in yeast systems biology. It is proposed to base this Network on a web resource that also provides a database of curated data, mathematical models and simulation tools. This web resource will allow the research community to contribute data as well as mathematical models to simulate biological processes. The community will then, through further experimentation, contribute to the recursive refinement of these models to advance our understanding of the biological process. The vision is to generate reference models of budding yeast, eventually at the level of the whole cell.YSBN will facilitate the cooperation between experimental and theoretical yeast researchers, and will stimulate the generation of quantitative data obtained in time courses and containing information on the spatial distribution of the individual components of the yeast cell. Defining the requirements for development of relevant experimental as well computational tools will be an important goal of YSBN. Furthermore, YSBN will take an active role in training and education, as well as ensure dissemination of systems biology activities to both the scientific community and the society.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Flavor Anomalies and the origin of the Yukawa couplings'.

assistant: **Innovation**

Recent experimental results in flavor physics exhibit deviations from the Standard Model predictions that are growing with time, both as far as statistical significance and as far as internal consistency. Understanding the origin of this phenomenon, the so-called “flavor anomalies”, is of paramount importance for a deeper understanding of fundamental interactions. As recently shown by the PI and collaborators, this phenomenon is likely to be intimately related to the long-standing “flavor problem”, or the origin of the hierarchical pattern of quark and lepton mass matrices observed in Nature. The goal of this project is to shed light on both these issues, providing a solution to old and recent puzzles in flavor physics. We propose to address these questions via an original bottom-up approach, based on Effective Field Theory methods and simplified models, combined with new top-down ideas about the ultraviolet completion of the Standard Model. On the phenomenological side, the proposed bottom-up approach will allow us to exploit with the highest accuracy all the available and expected experimental data. It will allow us to take into account both low- and high-energy observables, as well as both quark and lepton sectors. These results will constitute the basis for the theoretical investigation of a new class of Standard Model extensions not considered so far. The latter are based on new ideas, such as flavor non-universal gauge interactions, that imply a change of paradigm in theoretical high-energy physics: the origin of the flavor hierarchies plays a central role in revealing the ultraviolet completion of the Standard Model. Combining a bottom-up approach to flavor-physics data with top-down ideas on the origin of the flavor hierarchies, this project has the potential to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Role of N-kinase in regulating central nervous system regeneration' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

The proposed research will investigate the involvement of mammalian sterile 20-like kinase-3b (Mst-3b) in central nervous system (CNS) regeneration. It has previously been shown that the purine nucleoside inosine stimulates extensive axon outgrowth from certain types of neurons in culture and from injured brain pathways in vivo, leading to improved behavioural outcome.Pilot experiments in the outgoing host institution suggest that the target of inosine's actions is the protein kinase Mst-3b, and that suppressing Mst-3b levels or functioning inhibits the generation of neurites in culture.The main aims of this study are to investigate the role of Mst-3b in optic nerve regeneration in vivo and to investigate whether signalling through this kinase regulates the expression of a constellation of regeneration-associated genes. This project will use innovative, cutting-edge techniques such as adeno-associated virus transfection and microarray to alter/assess gene expression in vivo.The aims of this fellowship are- to advance our understanding of the basic mechanisms underlying regenerative success/failure in the CNS,- training of the fellow Barbara Lorber to become an independent scientist leading her own research group in Europe, and- to establish a, potentially long term, scientific collaboration between the outgoing host institution (Children's Hospital Boston (affiliated to Harvard Medical School), USA) and the return host institution (University of Birmingham, UK).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Chip-scALe visiBLE-iNfrared imaGing sEnsor', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

According to the World Health Organisation, road accidents are the eighth-biggest cause of death worldwide. Bad weather, dangerous road conditions, and distracted or fatigued driving account for nearly 70% of all accidents. Current Driving Monitoring Systems (DMS) and Advanced driver-assistance system (ADAS) underperform in harsh conditions, do not guarantee high standards of security and simply do not provide the needed supportive information to drivers: SWIR (Short-wave infrared) is what is missing. SWIR light, thanks to its peculiar physical properties, allows for better vision in critical visibility conditions such as fog, night, dusk and dawn.CHEERS - Chip-scALe visiBLE-iNfrared imaGing sEnsor- aims at developing a multi-spectral image sensor which, thanks to a unique patented electronic structure, is capable of selectively detecting the visible-near infrared (VIS-NIR) and SWIR regions of the electromagnetic spectrum. Being based on Si and Ge photodiodes monolithically integrated in a single device, EYE4NIR technology is fully compatible with mainstream foundry processes, harnessing their scalability and cost-efficiency to its advantage, as opposite tocurrent SWIR imaging technologies.The robustness of our approach is proven by very promising results on lab-scale prototypes.Within CHEERS, EYE4NIR, a fabless image sensor supplier, aims at manufacturing a first HD VIS/SWIR chip ready for high-volume productions. Target market is automotive where the demand for DMS and ADAS is growing (also because of regulatory constraints)and where price makes the difference. CHEERS is effective, reliable and versatile. Being an enabling technology, it can be implemented in other application domains such as industrial automation, consumer electronics and non-invasive quality control
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'E3Canarias: Enhancing the innovation management capacity of SME's with the Enterprise Europe Network Canarias' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The E3Canarias project aims at enhancing the innovation management capacity of the Canary Islands’ SMEs through the delivery of 7-day service packages, targeted to the most innovative small and medium size companies in the islands, as well as giving support to the Canarian beneficiaries of the HORIZON 2020 dedicated SME instrument, as Key Account Manager (KAM).Given the restricted number of packages available for the Canary Islands’ potential, the SMEs that have already been active in different innovation and internationalization activities will be assessed by using a standard innovation intake checklist and the SMEs with the most significant innovation activities and a high potential for internationalization will be selected.For the delivery of these services:• A minimum number of 2 EEN staff members will be trained for innovation management via the IMP3rove-Academy.• A minimum number of 7 service packages enhancing the innovation management capacities of SMEs will be provided. The final number of SMEs beneficiaries of the service could be increased depending on the resources available.• Considering the figures of participation of SMEs from the Canary Islands in the European Seven Framework Programme of RTD (FP7), a maximum of one beneficiary of the HORIZON 2020 dedicated SME instrument in 2014 is foreseen, so the expected provision of KAM service will be one. If the final number of SMEs is higher they will be supported as well.


**Keywords:** innovation, management, KAM
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Coordination of research into and understanding of stratospheric ozone over europe' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The overall result will be a European science programme funded by EC and national agencies which reflect the quality of European science in this area and complements research effort internationally. This, in turn, will result in an improved capability to quantify and predict ozone depletion.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Industrialised, Integrated, Intelligent Construction' under Sixth Framework.

assistant: **Concept**

Vision: The vision behind I3CON is to enable the transformation towards a European construction industry delivering Industrially produced, Integrated and Intelligent building systems that provide high performance spaces to building-users. I3CON's objective-driven approach: a new approach for industrialised production of building components with integrated services and intelligence will be created. These building components will be multifunctional, efficient, sustainable, reusable, interoperable and user friendly.The underlying new business model will shift current working practices from custom designed and craft made delivery to industrial production. The new business processes will create lifecycle value to building-users. Ultra high performance buildings will be delivered 50% faster and 25% cheaper, with lifecycle cost reductions of #gt; 40% and savings in repair and maintenance in excess of 70% together with enhanced comfort and security.Major breakthroughs:- Creation of a customer- and value-driven business model,- Industrialisation of construction and building lifetime processes,- Fully integrated smart systems and cross-system functionality,- A virtual building model for collaborative building engineering- Delivery of high performance spaces to building users- Branding of components and systems- Self-optimisation of life-cycle services and components- Step reduction in energy consumption and waste production Support through integration and further development of innovative technologies, intelligent materials and smart components interacting in distributed networks.Through the involvement of leading system integrators, suppliers, manufacturers and construction industry working together with building users in three different sector (Industry, Office-buildings and Pu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Multi-drug resistance in malaria under combination therapy: Assessment of specific markers and development of innovative, rapid and simple diagnostics' (MALACTRES), addressing dissemination and exploitation.

assistant: **Impact**

This project aims to assess specific P. falciparum genetic markers for resistance to artemisinin-based combinations (ACT), and to develop innovative, rapid and simple diagnostics for malaria and these markers. Specific objectives are: • To develop and evaluate in disease endemic countries accurate low-tech molecular diagnostic tests. • To identify alleles of candidate resistance genes associated with increased transmission success of P. falciparum after ACT treatment in completed clinical trials (endpoints at gametocyte or infected mosquito level). • To conduct ACT treatment trials with transmission endpoints, and measure impact of resistance-associated alleles on gametocyte emergence, and on the infectiousness of gametocyte-positive or randomly-selected treated individuals to Anopheles mosquitoes. • To measure ACT efficacy using in vivo treatment trials, and in vitro drug sensitivity testing of natural parasite isolates. The impact of candidate resistance markers will be measured in patients with treatment failure, and in parasites with reduced in vitro sensitivity. • To develop new low-tech diagnostic tools able to demonstrate the presence of mutations conferring drug resistance in the Plasmodium population, particularly those markers validated by the project. • To investigate commercial value aspects of developed tests. The project will move our knowledge of ACT resistance forward in 2 complementary ways:  1) In order to identify and validate genetic markers for ACT resistance, we will use our unprecedented access to parasites isolated both from ACT-treated individuals and from mosquitoes fed on blood from ACT-treated individuals.  2) we will develop and validate simple tests in new formats for detection of these and other markers of relevance, and for rapid detectio