RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The role of the influenza virus matrix protein M1 in budding adn virus release' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Enveloped viruses, such as influenza, acquire their outer lipid envelope by budding from the membrane of the infected host before being released in the extra-cellular space by membrane fission. In these last steps of the virus infection cycle, matrix proteins connecting capsid with the lipid envelope often play a key role in assembly and budding of newly produced virions. In spite of the widely acknowledged impact on public health and economy of influenza epidemics, the processes facilitating egression of the flu virus are only poorly understood. The goal of this project is to investigate the mechanisms by which Influenza escapes from its host. We will, in particular, focus on the role of its matrix protein M1. Our approach is based on the use of a combination of minimal cell membrane models produced in vitro upon self-assembly of lipids. Using supported lipid bilayers (SLB), giant unilamellar vesicles(GUV), as well as membrane nanotubes of compositions reflecting those of the host´s plasma membrane, we will provide a physical understanding to the role of M1 in facilitating virus assembly into a bud and release from the host. Through our study, we will elucidate whether M1 can promote budding and fission via scaffolding and whether the formation of lipid microdomains can help overcoming the energy barrier required for membrane abscission. Once the system is established, it will be extended to mimic the role the riboneucleoproteins core (RNPs), using nanoparticles of geometries similar to the viral capsid. Furthermore, the contribution of other viral components will be taken into consideration. In particular, we will look for a synergy between M1 and the ion channel M2 as the latter is believed to be involved in fission. A detailed understanding of the individual steps o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'High Entropy Metal Chalcogenides as Air Breathing Cathodes in Reversible Zinc Air Batteries (HEMZAB)' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

The growing concern regarding non-renewable fossil fuels and their adverse environmental impact has spurred the increasing exploration and utilization of renewable energy sources and the increasing development of energy storage devices. Within the energy storage systems, reversible batteries are the most performant in chemical-to-electrical energy transformation and vice versa. Currently, Li-ion batteries are dominating the energy storage market, though limited supply, high cost and safety concerns of the key material i.e. Li, is pushing the search for alternatives. In this regard, Zn-air batteries are the rising star of the future for Li-ion replacement. Yet there are two major challenges in the widespread adoption of Zn-air batteries: (i) sluggish oxygen redox (ORR/OER) reactions and (ii) instability of cathodic materials. This proposal will develop multi-component high entropy metal chalcogenides as bifunctional air cathodes having multiple active sites with tunable oxygen adsorption energies. Such a configuration will enable the facilitation of both ORR and OER effectively. In addition, it will enhance the stability of the cathodic catalysts. So the main goal of the project is to “Build a better Battery” by developing cost-effective, non-toxic and efficient catalysts that can boost the energy and power density of Zn-air batteries and enhance the stability of air cathodes. HEMZAB’s achievements will make advancements in cutting-edge Zn-air batteries that are pivotal to reaching the EU’s environmental targets for a reliable and green energy transition at a low cost.


**Keywords:** High entropy metal chalcogenides, Zinc air batteries, bifunctional catalyst, oxygen reduction, oxygen evolution reaction
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'SysTem for SAFE Biological chEmical Radiological and Nuclear Assessment, Rescue and Decontamination' (STBERNARD) targeting Horizon Europe.

assistant: **Abstract**

Emerging technologies on fast aerosol&vapour sensors and fast and massive decontamination -previously developed up to TRL5 by  participants of this proposal- have demonstrated to be ideal candidates to provide universal fast and portable protection against CBRN.This project will mature these safe technologies and develop operational procedures for detection, protection, decontamination and assessment itself, and will measure their effectiveness in experimental tests and practical demonstrations in operational environment (TRL7):EX Intrinsically Safe CBRN-E aerial drone with sensors, semiautonomous navigation even in denied GNSS and automatic detection of victims.Technology and operating procedures for sheltering responders (including vehicles) against CBRN-E toxic clouds and aerosolsMass decontamination of infrastructures and vehicles tech & procedures based on aerosol dynamic aggregation.Sensors and procedures for reliable assessment of cleanliness. Mass decontamination of people (i.e. crowded arena…)Decontaminator of Respiratory System of a victim or “Lung cleaner”.Operating procedures for safe CBRN-E debris removal and excavation.Additionally, after analysis of CBRN-E associated risks in rescue and recovery operations it will develop and validate an AI modular tool for generating operating procedures for first responders operating under a CBRN-E event.  These reliable useful tools and procedures at TRL7 will substantially increase safety for all first-responders (either CBRN specialized, non-specialized and even rescue-dogs) minimizing the need to enter in a contaminated area and exposure of first responder and providing smart advice and fused information. They haste a safe response and recovery reducing the number of victims and their severity as well as the environ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Strategies and self-regulation in children's reading comprehension' (1994-1998) under Fourth Framework.

assistant: **Objectives**

Research objectives and content The aim of this research is to explore the range of strategies for reading comprehension that are available to children in the age range 7-11 years. In particular, the relation between strategy use and reading comprehension skill, and the effectiveness of strategy training will be explored. An innovative aspect of the research will be the use of new (on-line) measures of children's strategy use during reading. This will also be the first extensive study of strategy use in children who have a specific comprehension problem. Training content (objective, benefit and expected impact) The proposed research will be conducted at the University of Sussex, which is a European centre of excellence for research into children's reading comprehension. Dr Oakhill, my proposed supervisor, is an internationally respected researcher, and the department at Sussex had a large postgraduate population and a well-organised doctoral training programme which is recognised by the Economic and Social Research Council (UK). The training will have two main components: participation (during the first year) in courses common to all postgraduate researchers, and regular meetings to discuss the progress of the specific research both with my supervisor and the research group more generally.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'European Network engaging CIvil society in Low Carbon scenarios' under Seventh Framework.

assistant: **Concept**

The overall aim of ENCI-LowCarb is to engage civil society in research on low carbon scenarios. This will be achieved by : - Creating a European network related to the factor 4 composed by Civil Society Organisations and research institutes - Elaborating two national studies (France and Germany) based on the confrontation between climate policies of low carbon scenarios and civil society organisations (social acceptability) - Disseminating the results to a larger public This project has direct relevance to the last developments of climate change european policies. The Spring Council of 8-9 march 2007 recognized that in order to stabilize the climate and to reach the 2°C objective, industrialized countries need to cut their greenhouse gases emissions by 30% by 2020 and by 60 to 80% by 2050 compared to 1990. In this context, the European Council endorsed an EU objective of a 30% reduction in greenhouse gas emissions by 2020 compared to 1990 as its contribution to a global and comprehensive agreement for the period beyond 2012. Policies able to reach these objectives still have to be conceived, and as there is not one single emission reduction objective common to each member state, there is no unique way to reach it. Discussions on this subject will take into account different national circumstances and potentials : French and German situations in particular will be analysed. But two main elements are decisive in implementing climate policies : of course their economic assessment, but also their social acceptability. The long term impact of the ENCI-LowCarb project will be to enhance the adoption by citizens and decision makers of the new behaviours which are required to reach the Factor 4 objective.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Evaluation of the residual fatigue life time in stainless austenitic steels'.

assistant: **Concept**

Research objectives and content Materials subjected to cyclic loading experience a change in the microstructure, which may affect the service life. The scope of the project is to increase the knowledge on the evaluation of the residual fatigue life time of austenitic stainless steels by characterization of the microstructure with defined fatigue strain and residual life time (microstructure, mechanical and physical properties) and qualification of non-destructive testing methods, which are sensitive to changes in properties and are useful for on-site application. The results shall show - the correlation between fatigue strain with different characteristics (low-high cycle fatigue) and the changes in the microstructure and - the sensitivity of different ndt-methods to follow the changes in the microstructure and to evaluate the usage factor. Training content (objective, benefit and expected impact) Within the scope of the research work the applicant shall link the results from mechanical fatigue testing with the changes in the macro- and microstructure of the austenitic stainless material. In addition to the already existing knowledge on mechanical and fatigue testing, the applicant will be trained for the methodologies of the examination of the macro- and microstructure by optical, scanning and transmission electron microscopy (TEM) and nondestructive test methods. The impact of the work will be on the application of the analytical transmission electron microscopy and nondestructive testing methods in the host laboratory. Links with industry / industrial relevance (22) The evaluation of the usage factor of components with possible fatigue strain during service is of great importance for the responsible operators of industrial plants (e.g. power plants, chemical industry
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Development of new antibacterial agents from natural toxins' (1998-2002).

assistant: **Innovation**

To solve the multidrug resistance public health problem, we plan to develop novel antibiotic from the natural E. coil Cod toxin. For that purpose, we will characterise interaction (s) between Cod and its target DNA gyrate and study Cod toxicity in species responsible for multiresistant infections.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'AIRBORNE AIR TRAFFIC MANAGEMENT SYSTEM' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

The purpose of AATMS is to bring the European avionics (aircraft electronics) industry a big share of the on-board telematics equipment market for future air traffic management and control. The project will demonstrate an airborne traffic management system with an emphasis on data links, communication management and on-board operations. Modules for demonstration will build where possible on existing equipment or software. They will be integrated and validated in flight trials. Industry will be in a position to start product development as a consequence of widespread dissemination of project results.For a European avionics industry, the capability to develop an onboard architecture for the future CNS/ATM (Communications, Navigation and Surveillance/Air Traffic Management) environment is of strategic importance, being the focal point of future onboard systems and therefore dominating cockpit avionics. Therefore, the project will prepare the European avionics industry to gain a significant market share. In the course of the intended project, a demonstrator for an Airborne Air Traffic Management System (AATMS) will be developed and evaluated. The proposed work will focus on data link realisation and communication management and onboard CNS/ATM functions that are compatible with the future European air traffic environment, including flight plan negotiation and 4D planning/guidance.The 36 month project starts with the identification of the user needs. In this context the involved partners can build on great experience from related projects, in which the user needs for future onboard CNS/ATM systems have been assessed. This consolidation of user requirements is followed by the functional CNS/ATM specification in order to identify and assess possible onboard architectures and t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Strengthening the Romanian research capacity in Multifunctional Polymeric Materials' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Within the STREAM project, PPIMC aims at further strengthening its research capacity in the targeted scientific sectors by means of mobility and knowledge exchanges with excellent research EU institutions, participation and organisation of scientific events, hiring of experienced researchers, up-grading of its laboratories and networking with both industry and other research organisations, but most of all through a complete reshaping of its internal organisation. PPIMC ambitions are to adopt a totally integrated interdisciplinary approach around four research areas, defined by the Institute as priorities, in order to converge towards excellence on a crucial topic: “high added value multifunctional polymeric materials: concepts, mechanisms, properties, application”.The project will strengthen the research excellence of the institute and will therefore increase the attractiveness of the scientific career for young researchers in Romania. Further, the project will reinforce the capacity of business and governmental exploitation of research results and cooperation with industry and will set up a bridge between the Romanian chemical network and the European Research Area.In order to meet the main goal to improve the research potential at PPIMC, STREAM plans to reinforce and strengthen the established collaborative links with leading European institutions undertaking research and practice in Polymer Science. A complex schedule of exchange visits at different scientific level will allow the transfer of knowledge in the area of planning according to the social needs, management and supervision of strategic research activities in the concerned field. Within the STREAM proposal PPIMC will collaborate actively with 13 research centres from France, Germany, Poland, Slovenia, Spain
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'New chemical building blocks for de-icing and anti-icing of car windows' in the context of a Horizon 2020 call.

assistant: **Objectives**

Ice accretion of car windshields is a road safety concern in fall and wintertime as frost impairs the vision of drivers that do not sufficiently de-ice their car windshields, which may cause serious road accidents. Windshield washer fluids are crucially important for rapid car windshield de-icing which is most efficient through a combination of thermal, mechanical, and chemical action; i.e., local heating, scraping, and the application of appropriate windshield washer fluids. At present, windshield washer fluids rely solely on colligative antifreezes. The current formulations are (highly) flammable which requires precautionary measures in stores and cars, and the ethanol used is derived from sugarcane which is a valuable food resource. The challenge is to develop a commercially viable solution to replace these colligative antifreezes by an innovative screenwash formulation that is highly effective, but not flammable, does not present a health risk, and does not use food resources. In ‘PRicelessCOAT’ scientists will develop new biocompatible and biodegradable chemical building blocks for de-icing and anti-icing of car windows.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Gene therapy for treatment of Parkinson's disease : functional and cellular evidence' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Parkinson\'s disease is characterized by the progressive loss of the dopaminergic neurons in thesubstantia Ingra pars compact which results in functional changes in structures of the basal ganglia such as the sub thalamic nucleus, the entopeduncular nucleus and the substantial Ingra pars reticulata. Current therapies involve dopamine pharmacological treatment, deep brain stimulation and fatal cell transplantation. Though these approaches reach significant beneficial effects, they are however hampered by numerous limiting factors such as side effects or difficulties related to the methodology. Since a few years, significant progress has been made in the field of gene therapy for Parkinson\'disease, focusing on two main strategies: the replacement of biosynthetic enzymes for dopamine synthesis and the addition of neurotrophic factors for protection and restoration of dopaminergicneurons. Although successful vehicles have been developed and efficacy and safety have been shown in various animal models of Parkinson\'s disease, the cellular and molecular mechanisms underlying these benefits at different levels of the basal ganglia are so far incompletely known. This project will thus aim at characterizing these mechanisms particularly in the sub thalamic nucleus, entopeduncular nucleus and substance Ingra pars reticulate and evaluating the more efficient strategy which might be used inhuman therapy ursine combination of several strategies.'