RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Generation of highly informative DNA markers and genetic marker maps of Salmonid fishes - SALMAP' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Production and characterisation of highly informative DNA markers with particular stress on micro-satellites in Atlantic salmon (Salmo salar), rainbow trout (Oncorhyncits mykiss) and brown trout (Salmo trlitta). Run characterised markers through reference families, some of which also are typed for alloenzymes, to provide recombination data for linkage analysis. Typing of traditional, diploid pedigrees will allow for sex linkage analysis. Carry out genetic linkage analysis and construct species-specific low-resolution genetic maps, embracing mostly anonymous markers but also enzyme loci (rainbow trout). Depending on the success rate of cross-reacting markers and the degree of inter-specific conservation of marker linkage groups: identify anchor loci in a comparative Salmonid map.State of progressAt the end of the first reporting period of the project the state of progress is as follows:Atlantic salmon: 278 (256 from Atlantic salmon + 22 from rainbow trout) micro-satellite loci have been identified and partially characterised and so far 55 (38 from Atlantic salmon + 17 from rainbow trout) have been fully characterised. No markers have been genotyped in the reference families since these will be slaughtered in month 14 and DNA made available in month 15 or 16.Rainbow trout: 172 (155 from rainbow trout + 17 from Atlantic salmon) micro-satellite loci have been identified and 124 (116 from rainbow trout + 8 from Atlantic salmon) have been fully characterised. 108 micro-satellite loci and 6 RAPDs have been genotyped in reference families resulting in the identification of 20 linkage groups by the Canadian group and 2 linkage groups were identified by the French group.Brown trout: 89 micro-satellite loci from rainbow trout (50) and Atlantic salmon (39) have been identified and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'A Novel Approach to Source Monitoring in Digital Intelligence-Enhanced Witness Interviews for High-Stakes Investigations' (MTC) under Horizon Europe.

assistant: **Objectives**

Modern digital technology provides unprecedented access to real-time intelligence: social media posts, CCTV footage, mobile phone data, geolocation information, and digital communications networks. Investigators increasingly share this digital intelligence with witnesses to enhance memory retrieval and gather critical information under severe time constraints. Given the abundance of PEI from external sources including investigator-shared digital intelligence, it is imperative for witnesses to monitor the sources of their memory during forensic interviews. To help witnesses with monitoring their memory sources when reporting, psychologists have been using source monitoring techniques, such as giving people an explicit source monitoring warning (e.g., ""please report only what you witnessed during the crime, not information from media reports or other post-event sources""). However, current source monitoring techniques assume PEI comes from external sources, not from investigators deliberately sharing digital intelligence during the interview. Memory Tracking in Crisis (MTC) addresses that critical gap head-on, developing and testing a groundbreaking memory mapping tool designed specifically to help witnesses navigate the complex digital landscape of modern terrorism investigations.""


**Keywords:** Memory enhancement, Evidence-based memory tool, forensic investigations, high-stakes cases, memory recall performance
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'FAMILY-FOCUSED ADOLESCENT & LIFELONG HEALTH PROMOTION' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Young people in Eastern Europe face risks to their health and wellbeing due to factors including violence, poverty, inequality, and other adverse experiences, exacerbated by the ongoing conflict in Ukraine. Programs focusing on the adolescent-caregiver relationship are an evidence-based solution to supporting adolescent health by addressing a cluster of common individual and family risk factors. Parenting for Lifelong Health (PLH) is one such program, developed for implementation and scale-up in low-resource settings. FLOURISH will adapt, implement, and evaluate the PLH Teens program. The program will be adapted to the service delivery and cultural setting of two countrywide health networks, in North Macedonia and Moldova, including the needs of the refugee populations from Ukraine. The program covers evidence-based skills, such as problem-solving and emotional regulation, for adolescents 10-14 years old and their caregivers. Through building skills and strengthening the adolescent-caregiver relationship, communication, and caregiver monitoring, the program has the potential to prevent and reduce multiple common mental health problems and risk behaviors, such as alcohol misuse, therefore reducing the risk of future non-communicable diseases. Informed by co-production with stakeholders and intervention process evaluation, FLOURISH will explore the cost-effectiveness of intervention components and test the final intervention package in a hybrid implementation-effectiveness randomized trial, as well as develop a scaling strategy informed by qualitative data and statistical modeling. The project will foster methodological innovation. FLOURISH will advance the uptake and scale-up of evidence-based, open-source, and sustainable family interventions for adolescents in low-reso
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Harnessing Stromal Fibroblasts to Reduce Resistance and Improve Colon Cancer Therapeutics' in the context of a Horizon Europe call.

assistant: **Objectives**

Refractory tumors and emergence of drug resistance are the most important challenges in cancer therapeutics. The non-cancerous determinants of therapeutic response and particularly the role of the tumor microenvironment (TME) in resistance are poorly understood. I previously described the crucial role of cancer-associated fibroblasts (CAFs) in key tumorigenic processes, including matrix remodeling, cancer cell invasion and growth. Importantly, these aggressive CAF phenotypes are controlled by mechanical reprogramming and mechanotransduction pathways. Within therapeutic resistance contexts, I hypothesize that preexistent and therapy-induced aberrant activation of mechanotransduction signaling in CAFs leads to the generation of refractory TMEs affecting cancer cell signaling and the behavior of accessory stromal cells such as endothelial and immune cells. As a result, tumors will present: (i) abnormal vasculature associated with reduced drug perfusion and chemotherapy efficacy; (ii) increased production of pro-survival signals affecting targeted therapy; and (iii) inactivation of cytolytic T cells and reduced responses to immunotherapy. I propose that CAF-based biomarkers will improve our capacity to identify patients most likely to respond to these therapeutics. In addition, targeting mechanotransduction in CAFs will significantly increase efficacy in non-responders. Focusing in colorectal cancer, I will use patient-derived CAFs as a tractable system and organ-on-chip, in vitro and preclinical models of CAF-mediated resistance, and combinatorial chemistry to systematically elucidate the molecular and biological features conferring CAFs their privileged therapy-resistance properties. This will illuminate novel and general mechanisms whereby TME characteristics influence t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Synthetic Lives: The Futures of Mining' in the context of a Horizon 2020 call.

assistant: **Objectives**

The global extractive industry is undergoing three critical transformations: first, the advent of synthetic or lab-grown minerals, impacting the mining industry and the extraction of resources from nature; second, the creation of fully automated mining operations, seeking to render human work redundant or accessory to that of bots, drones, and other autonomous machines; third, the introduction of digital data and disintermediation technologies for mining management and traceability. Taken together, these innovations anticipate a future of mining that replaces nature with synthetic substances, human labor with intelligent machines, and intermediaries with unmediated accountability. This project responds to these changing conditions with a novel conceptualization of the emergent relationship entangling synthetic and natural objects, humans and machines, material and digital spaces: Synthetic Lives. It asks: What is the role of humans and non-human nature in increasingly synthetic, automated, and digital mining economies? This research innovates by bringing together three related areas of scholarly enquiry: i) resource materialities, to destabilize the divide between nature and culture; ii) mediation and technology, to problematize the separation between humans and machines; iii) algorithmic governance and digital transparency in mining sites, to untangle how material and digital properties are co-produced. Through a multi-sited and multi-methods study, it contributes to these fields of research in three case studies: synthetic laboratories, automated mines, and digital and data-driven mining processes. Interlacing these three foci, Synthetic Lives assists policy-making on environmental, employment, and social-digital issues, and inaugurates a debate of anthropological imp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Development of an Auxetic, antiMicrobial, suPramolecular coordination poLymer as a meta-materIal For bIomedical applications' (AMPLIFI) under Horizon 2020.

assistant: **Objectives**

AMPLIFI aims to develop an innovative auxetic, antimicrobial meta-material based on a supramolecular coordination polymer for the design of biomedical devices. Auxetics are unique due to their negative Poisson’s ratio, which imparts superior mechanical qualities when compared to conventional materials. They offer huge potential if used to design biomedical devices such as catheters. There is as yet no synthetic material that demonstrates auxeticity at the nano-level, even if potential auxeticity was demonstrated through simulations. Through AMPLIFI I will design a polymeric structure with superior mechanical strength that offers better patient comfort by virtue of its auxetic properties while also dealing with the challenge of bacterial infections. The project exploits the versatility of supramolecular chemistry of calixarenes or related macrocycles and self-assembly. Appropriate building blocks for a self-assembled auxetic polymer will be identified by MM simulations, and the effect of adding antimicrobial agents studied. The identified coordination polymer will be synthesized, fully characterised and subsequently tested for antimicrobial properties. I have a strong background in supramolecular chemistry which makes AMPLIFI an ideal project for me, and I will be joined by a strong supervisory team at the University of Malta consisting of an expert in auxetics, a renowned microbiologist and a structural chemist. AMPLIFI also boasts of the co-supervision of a leader in calixarene and related macrocyclic chemistry from the University of Parma. AMPLIFI builds on my expertise and enables me to work within a multidisciplinary team at the interface of theoretical chemistry, experimental organic synthesis and microbiology. In short, AMPLIFI provides me with a holistic research
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'WATER OXYGENATION WITH PHOTOVOLTAIC ENERGY' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

The objective of this project is to solve an environmental problem by using photovoltaic energy. It consists in bringing air into the lake Valencia with oxygenators. These oxygenators permits the rise of the purification of the organic materials and the regeneration of the flora and fauna of the lake. Also the reduction of bad smells coming from the rotten water will be minimised, as well as the progressive destruction of the aquatic life.Innovative in this project is the Oxygenators SO-100 which is able to generate a curtain of air-bubbles with a air-volume proportional to the solar radiation received at every moment on the solar modules.The functioning of the system basically consists in generating electricity by the solar panels. These solar panels feed through the converter (which changes the tension of the solar panels, 2X53W, into the tension of the electric engine) a DC engine which mechanically (by pulleys) drives a volumetric air compressor that pushes the air into the diffuser upon two floating structures of fiber-glass what will make it very easy to move and to install the system in any other location independently to the nature and depth of the lake.The system with the solar panels and the tension converter permits the engine, whose functioning is proportional to the received solar radiation on the panels, to work independently.This proportional function allows us to omit batteries. This configuration (free of maintenance) does not need neither the assistance of a accumulator, nor its substitution when the active life of the accumulator ends.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Use of innovative strategies for beta-cell imaging in diabetes mellitus'.

assistant: **Concept**

The development of sensitive, non-invasive methods for the characterisation and quantification of beta-cell mass would greatly enhance our means for gaining understanding of the pathophysiology of diabetes and allow the development of novel therapies to prevent, halt and reverse the disease. The aim of this project is to develop and apply innovative approaches for beta-cell imaging, the emphasis being on beta-cell mass regulation (loss and neogenesis) with the perspective of entering initial clinical trials. For this purpose, our approach is to: (1) Focus on imaging technologies offering the potential to enter clinical trials during the runtime of the project. Since beta cells contribute only marginally (1-2%) to the total mass of the pancreas, a highly sensitive method for clinical imaging is required. BETA IMAGE will focus on positron emission tomography (PET) relying on chemical resolution, i.e. the specificity of a radiolabelled tracer molecule. The lead compound will be radiolabelled Exendin 4, developed in the consortium for GLP-1 receptor imaging. (2) Devise novel imaging strategies by generating labelled “design” molecules/peptides/nanobody molecules targeting newly identified beta-cell surface proteins. These targets will be identified using a Systems Biology approach. For high-throughput tracer development, a stream-lined methodology will be established based on in vitro model systems and micro-/macroscopic in vivo real time dynamic imaging of tracer distribution by optical coherence tomography and complementary small animal PET and MRI. (3) Build on European excellence in tracer development using peptides, peptide-like and organic molecules for different imaging modalities. To achieve these ambitious goals, we have established a highly interdisciplinary and i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Providing services under Horizon 2020 enhancing the innovation management capacity of Hungarian SME's within the framework of the Enterprise Europe Network - 2019' under Horizon 2020.

assistant: **Concept**

The global objective of the ""Providing services under Horizon 2020 enhancing the innovation management capacity of Hungarian SME's within the framework of the Enterprise Europe Network - 2019"" project is to effectively contribute to the innovation driven competitiveness and sustainable growth of the European economy via improving the innovation management processes and culture of Hungarian SMEs by enabling them to get their products, services successfully into the market. The concept of this project focuses on the development of Innovation Management capabilities via two different types of high-added value services: • “Key Account Management” for the beneficiaries of the SME Instrument, Future and Emerging Technologies Open (FET-Open) and Fast Track to Innovation (FTI) programs• “Enhancing SME innovation management capacity” with the usage of IMP3rove and Innovation Health Check tools/methods.Partners delivering services are members of the Hungarian Consortium for Enterprises (HCE). Their in-depth innovation management portfolio will be accessible for SMEs from all parts of the country.  ""


**Keywords:** Enterprise Europe Network, Horizon 2020, Key Account Management, Enhancing SME, innovation management capacity, SME Instrument, FET, FTI, IHC, IMP3ROVE
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Next generation quantum dot materials and devices' (NEXTDOT) targeting Sixth Framework.

assistant: **Abstract**

The proposal will lead to significant advances in the general area of QD research. Improving the understanding of current QD materials and devices is crucial towards enabling this technology to reach its full potential. This understanding will emerge from the extensive experimental program foreseen, which includes detailed gain and refractive index measurements as a function of temperature from 77K to above room temperature, femto-second pump probe spectroscopy to determine the fundamental timescales of the se novel structures and careful analysis of the efficiency and transport properties of these devices to reveal their fundamental transport and loss processes.This information will greatly aid the development of new quantum dot material structures such as those based on Antimonide substrates and dot-in-a-dot structures. These materials will be the first of their kind in the world and the researchers role will be key in providing feedback to both fabricators and designers. Through this interaction, great progress will be made in the practical realisation of the great benefits of quantum dot materials and their extension to new wavelength ranges.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The long-term effects of unemployment on older workers: Studying life-course influences in social context' under Horizon 2020.

assistant: **Concept**

Europe’s population is currently the oldest in the world, and it is still ageing. This demographic shift is changing societies in an unprecedented way. Researchers and policy-makers fear that we will now only have sustainable pension schemes and a sufficiently numerous, well-qualified workforce if people work until old age. Consequently, many current policies strive to increase workforce participation and delay retirement. But can such policies for older workers be effective? Life-course scholars argue that experiences have time-delayed effects. What people experience during youth and mid-age influences whether they work in old age. Thus, policies for older workers may intervene at too late an age to make a difference. This study investigates time-delayed effects on older workers. It focuses on the effects of unemployment spells, which are said to scar work biographies and permanently hamper careers. This study uses the life-course perspective and thereby joins the newly emerging group of empirical studies that consider entire work biographies to explain workforce participation in old age. Its unique contribution is that it considers the role of social context in the form of families and economic crisis. Family members often coordinate their workforce participation and retirement timing. Economic crises increase unemployment rates, which affects the meaning and experience of being unemployed. This study compares the “most different cases” of Finland, Germany, Italy, Poland and the United Kingdom. Data stem from life-history interviews in the “Survey of Health, Ageing and Retirement in Europe”, the “English Longitudinal Study of Ageing”, and a self-administered Finnish survey. The approach combines sequence, cluster, regression and correlation analyses. Findings refine t