RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Spin and Many-Body Interaction Phenomena in Semiconductor Nanostructures'.

assistant: **Objectives**

We propose systematic extensive investigations of many-body spin phenomena in semiconductor nanostructures, with a goal to find effective magnetic/spin mechanisms to tailor various electronic anisotropies, potentially useful in device structures. The two principal Bychkov-Rashba (BR) and Dresselhaus (D) spin-orbit interactions (SOI) will be explored. We plan to calculate the anisotropy of the Friedel oscillations and of the many-body renormalization of the electron mass. We propose to design a device scheme to control the effective mass through the relative strength of the BR and D couplings. We’ll study the effect of exchange and correlations on the SOI induced anisotropy of plasmons. Another goal is to investigate the SOI effects on the charge and spin Coulomb drag (CCD and SCD). We'll focus on two effects, related to (i) the new drag channel, induced by the inter-chirality transitions, and (ii) the dominance of large-angle-scattering events in CCD and SCD. This requires accurate calculations with the use of the exact Lindhard polarization function. Recently we have shown that SCD is suppressed in wide quantum wells. Here we propose to study a crossover from Coulomb to phonon-mediated spin drag with an increase of the carrier density and the well width. Another goal, related to the phonon system, is the calculation of spectral and damping properties of new complexes, coupled plasmon-optical phonon modes, in the presence of BR+D SOI. Next we propose to study spin phenomena in hybrid ferromagnetic-semiconductor nanostructures. We will focus on the SOI induced modifications of the magnetic edge states (the snake and cycloid orbits of electron spin) and on the induction and manipulation of spin currents along magnetic interfaces. Finally, we’ll study side jump SOI as a me
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Identification and functional characterisation of novel APC binding partners'.

assistant: **Objectives**

Adenomatous polyposis coli (APC) is an important tumour suppressor in the human colon epithelium: its loss of function is known to be a primary cause of tumourigenesis, accounting for more than 80% of all heritable and spontaneous colon cancers.The first significant clue for APC function emerged when its association with b-catenin was discovered, providing a molecular link between APC and the Wnt signalling pathway.The Wnt-signalling cascade is strictly conserved from flies to mammals and controls decisive steps in development and homeostasis of tissues and organs. APC is involved in the regulation of b-catenin at the protein level and the nuclear shuttling of b-catenin.However, the molecular mechanisms underlying this functions are far from being solved a t present. APC also associates with the plasma membrane at adhesive sites in polarized epithelia. Recent work in mammalian cells and the characterisation of a loss-of-function mutation in Drosophila E-APC suggest novel roles of APC in intercellular adhesion and cell migration.This proposal combines genetic and biochemical screens to identify most, if not all genes involved in APC function. In particular, we aim to identify APC-binding partners whose binding is abrogated by the (loss-of-function) N175K mutation of E-APC.This will provide novel insights into the molecular mechanisms underlying this loss-of-function mutation. The thorough characterisation of identified genes will lead to a better understanding of Wnt-signal transduction, but also uncover the variety of APC's cellular functions.The analysis of APC's role at the plasma membrane and its putative impact on regulating cellular adhesion may have important implications for human malignancies, as they may contribute to tumour progression and metastasis.Our goal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'gamma-MRI: the future of molecular imaging'.

assistant: **Innovation**

Gamma-MRI will develop a clinical molecular imaging device based on the physical principle of anisotropic gamma emission from hyperpolarised metastable xenon. In the strategic move from “one size fits all” to personalised medicine, molecular imaging plays an essential role. However, despite significant technological advances in the last decades, medical imaging (especially for the brain) relies heavily on very expensive, complex and bulky machines. Moreover, MRI suffers from low sensitivity, only partially compensated by the recent advances in hyperpolarisation. On the other hand, the very sensitive PET and SPECT imaging modalities offer limited spatial resolution. Besides those trade-offs, the limited access to suitable devices still hinders the applicability of medical imaging to address major healthcare challenges in brain-related pathologies, even in Europe. Stroke alone is the second cause of death and the third cause of disability worldwide. The evolution of ischaemic damage varies much among patients. To achieve significant improvement in the outcome of the patients, a careful selection of the treatment path guided by images of the ischaemic brain, in a narrow time window of just a few hours is crucial. Unfortunately, point-of-care molecular imaging that could speed up patient management barely exists. Gamma-MRI is a game-changer imaging technology, combining the high sensitivity of gamma ray detection and the high resolution and flexibility of MRI, bringing down by multiple fold the cost of molecular imaging. Six closely interlinked work packages will cover: production of hyperpolarised gamma-emitting xenon isomers; preserving hyperpolarisation until delivery to targeted organ; developing advanced image acquisition and reconstruction using physics- and artificia
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Novel optical nanocomposite sensors for analysis of micro and macro elements in corn plants' (SENS4CORN).

assistant: **Concept**

SENS4CORN is targeted to strengthen intersectoral and interdisciplinary collaboration in optical composite nanomaterials for optical chemical sensors. The main project goal is development of novel optical nanocomposite sensors for analysis of micro and macro elements in corn plants. We will investigate Schiff bases (SB) and Metal organic frameworks (MOF), optical composites ZnO-SB and ZnO-MOF with advances optical and their sensitive properties towards anions and cations, present in corn micro and macro elements. The sensitive composites will be integrated into microfluidic system, combined with fiber optic detection system. The system will be used to validation of real corn samples. The sensing system will reduce time and cost of the measurements by standard chromatography methods. The sensing system has good potential of commercialization in agriculture sector as a new rapid service for corn growth analysis for small and medium farm companies. The project is interdisciplinary and it involves material science, chemistry, surface science, optical, analytical chemistry, nanotechnology and agriculture. The project will create new service for improvement of agriculture production, thus improving industrial and health potential of EU citizens. During the project, research and management training will be provided to technicians, experienced and early stage researchers to strengthen their personal skills, improve their track record and expertise via new scientific papers and conference presentations and strengthen a development of EU research human resources. Long lasting collaboration between partners, based on co-supervising students and preparation of novel collaborative project proposals is foreseen. Dissemination of project results will make an impact on agriculture sect
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Symmetry preserving discretization of integrable, superintegrable and nonintegrable systems'.

assistant: **Innovation**

The aim of this project is to develop and apply efficient mathematical tools for studying quantum and classical phenomena in a discrete setting. The motivation is on one hand that on the fundamental level it seems that space-time is discrete, because of the existence of the Planck length and its role e.g. in quantum gravity. On the other hand, even in a continuous world many important phenomena are discrete, such as phenomena occurring in crystals or in molecular or atomic chains. Thus difference equations may be more fundamental than differential ones. Moreover, differential equations often have to be solved numerically and that means that they have to be discretized, i.e. approximated by a difference system.Our main interest is in models that can be solved exactly because of their symmetry and integrability properties. Of special interest are finite and infinite dimensional integrable and superintegrable models. Integrable systems have as many commuting integrals of motion as degrees of freedom (which may be infinite). Superintegrable systems have more integrals of motion than degrees of freedom and these integrals form interesting non-Abelian algebras. The integrals of motion are related to symmetries of the system. These may be Lie point symmetries but usually they are generalized symmetries and they form more general algebras than Lie ones. Our aim is to study and use Lie symmetries of difference equations and to discretize differential equations preserving their most important properties. These include their Lie point symmetries, generalized symmetries, integrability and superintegrability.In order to do so we plan to host a top-class researcher from a Canadian first class laboratory who is a founder and an expert in the field of symmetry preserving discretization
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Zinc effects on nutrient / nutrient interactions and trends in health and ageing.'.

assistant: **Concept**

Intake of protective nutritional components, including zinc, is critical for older people. Zinc enrichment may be beneficial for health, but excess zinc may interact with Fe and Cu metabolism. We propose to determine the response to nutritional supplementation of zinc in cohorts of late middle-aged and older men and women from different European countries. Volunteers will receive a placebo or two levels of zinc supplement for 6 months. Effects of zinc supplementation on relevant micronutrient status and intestinal absorption of zinc will be evaluated. Cognitive function and psychological and physiological factors will be monitored. Beneficial effects and possible adverse effects, on surrogate biomarkers of health and physiological factors, will be detonated at baseline, 3 and 6 months of zinc supplementation. This proposal will provide a scientific basis for formulation of public health recommendations on dietary zinc intake in ageing Europeans.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Biophysical aspects of self-organization in actin-based cell motility' (BIOSELFORGANIZATION) under Seventh Framework.

assistant: **Objectives**

Cell motility is a fascinating dynamic process crucial for a wide variety of biological phenomena including defense against injury or infection, embryogenesis and cancer metastasis. A spatially extended, self-organized, mechanochemical machine consisting of numerous actin polymers, accessory proteins and molecular motors drives this process. This impressive assembly self-organizes over several orders of magnitude in both the temporal and spatial domains bridging from the fast dynamics of individual molecular-sized building blocks to the persistent motion of whole cells over minutes and hours. The molecular players involved in the process and the basic biochemical mechanisms are largely known. However, the principles governing the assembly of the motility apparatus, which involve an intricate interplay between biophysical processes and biochemical reactions, are still poorly understood. The proposed research is focused on investigating the biophysical aspects of the self-organization processes underlying cell motility and trying to adapt these processes to instill motility in artificial cells. Important biophysical characteristics of moving cells such as the intracellular fluid flow and membrane tension will be measured and their effect on the motility process will be examined, using fish epithelial keratocytes as a model system. The dynamics of the system will be further investigated by quantitatively analyzing the morphological and kinematic variation displayed by a population of cells and by an individual cell through time. Such measurements will feed into and direct the development of quantitative theoretical models. In parallel, I will work toward the development of a synthetic physical model system for cell motility by encapsulating the actin machinery in a cell-si
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Toward Tough Amorphous Electrolytes and Stable Interfaces in Solid-State Batteries' (TOUGH).

assistant: **Concept**

Renewable wind and solar energy production and electrification of transport require battery systems to store the electricity until it is needed. Lithium batteries have been very successful, but further improvements are needed in terms of safety, performance, efficiency, cost, and lifetime. The use of solid instead of liquid electrolytes offers a key step forward, but slow kinetics is the Archilles’ heel of solid electrolytes. This problem can be addressed by using amorphous (disordered) instead of crystalline electrolytes, but in turn these suffer from low fracture resistance, compromising long-term performance.In the proposed project, we will elucidate the mechanical behavior of amorphous solid electrolyte/electrode interfaces. The aim is to optimize the electrolyte composition and structure to simultaneously achieve high toughness, stable interfaces, and high lithium ion conductivity. To this end, we will first understand the structure-conductivity relations in disordered and partially ordered sulfide electrolytes (Task 1). Then the mechanical properties of the individual phases and interfaces will be explored in constructed all solid-state batteries (Task 2). These experiments will be complemented by atomistic simulations to understand the structural changes in the investigated systems during battery operation (Task 3).The project builds on complementary expertise of the fellow applicant (battery materials) and supervisor (mechanics, amorphous materials). Together with the research and training environment provided by the host organization (Aalborg University, Denmark), this will ensure the achievement of this timely and innovative project as well as the dissemination and exploitation of the expected results. These research outputs will lead to new amorphous material
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Improving energy efficiency and reducing carbon emissions by utilization of ultra-cold energy from the regasification of liquefied natural gas (LNG)' (LNG) under Horizon 2020.

assistant: **Objectives**

Cost-efficient and environment friendly provision of cold for industry, food handling, shipbuilding, and LNG (Liquefied Natural Gas) fuelled trucks is a rapidly growing market opportunity. Electrical refrigeration and air-conditioning consume almost 25% of the electrical energy in Europe, a tremendous saving potential and attractive business opportunity for new technologies. Eco ice Kälte GmbH develops technologies to exploit this attractive market potential, to generate significant growth and with this contribute to achieving the climate targets. One very promising approach results from the globally rising use of LNG as energy source, since a huge cold capacity at -162°C is stored in LNG, which is hitherto completely wasted during the regasification by heat exchange with ambient air or sea water at port terminals and LNG end user’s sites, respectively. Eco ice has developed and patented an innovative technology (TRL6) in various output classes to recover this highly valuable cold capacity without additional electrical power or gas consumption and provide it very cost-efficiently to the market.The Eco ice technology has the potential, without any self-consumption of natural gas, to create electrical power savings of 5.000 MW, i.e. to replace the fossil fuels for several large power stations. The cold market is increasingly looking for such cost-efficient and eco-friendly alternatives, as confirmed by customer feedback. Even in a conservative business scenario, which assumes a technology conversion rate of only 5%, a profitable short term growth up to a high two digit million € revenue value can be expected, as confirmed by ongoing negotiations with potential launching customers and business partners. The proposed feasibility study aims at completing the market study, co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Development of a Numerical Model for Wind-Assisted Ships - FSI Modelling and Fatigue Analysis Towards Sustainable Ship Propulsion' (NuWAS).

assistant: **Concept**

The global maritime industry faces a challenge with the International Maritime Organization's 2023 strategy to achieve net-zero emissions from ships by 2050. Wind-assisted propulsion technologies have emerged as a promising solution for reducing fuel consumption and environmental impact. This research project focuses on numerically predicting the dynamic fluid-structure interaction (FSI) of wind-assisted ships (WAS), to determine the fatigue life of windsails.The project aims to address critical challenges in implementing wind-assisted propulsion systems through innovative numerical methods and advanced simulations. The main objective is to study the interactions between wave-induced ship motions and the aerodynamic performance of a wingsail. The project will investigate the impact of different levels of FSI coupling on the structural responses and cyclic loading experienced by the wingsail. This will enable the assessment of how simulation fidelity (i.e., the degree of FSI modelling) influences the fatigue life analysis and structural design. The outcomes will enable informed decision-making regarding wind-assisted technologies and support structural design optimization. These findings will support the maritime industry’s efforts to meet IMO emissions reduction targets and contribute to decarbonizing global shipping.The project will advance my career by building on my numerical modelling background and utilizing the cutting-edge facilities at the University of Southampton. The university’s expertise in numerical modelling and maritime engineering will support successful research completion. Dissemination will target scientific communities in fluid dynamics and maritime engineering for immediate impact. By tackling technical and economic challenges of wind-assisted ship