RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Total service for the machine tool end user' (SMART) under Fifth Framework.

assistant: **Objectives**

The manufacturing paradigm is changing, and the production means must evolve to the new needs. The target of project SMART is to solve the needs and problems of the end-users of the machines and the ways the manufacturers offer new added value services, mainly small and medium enterprises. In this way, the project will contribute to the modernisation of those SMEs by enhancing the innovation capacity.The SMART project will undertake the manufacturers need to offer a better service to the client, not only when a failure occurs but also for helping to improve the machining process and the operation of the machine. This project also intends to set the basis to take the maximum advantage of the opportunity given by the new numerical controls of machine tools and the opportunity to integrate intelligence into the machine tool providing higher reliability, higher process safety and lower efforts for service.The project established the basis for agent implementation and produced some immediate results, but also started agents development. The resulting agent prototypes have reached different development stages: Machine Access Agent, Data Logging Agent, Visualization Agent, Monitoring Agent, Preventive Maintenance Agent are completely available; For the other agents a prototype is available; the development will go on after the project end, so that a marketable product will be ready some time after project end: Machine Diagnostic Agent after 6 months; Machine Tuning Agent, Operator Assistance Agent, Manufacturer Service Agent after 1 year Manufacturing Planning Agent; Hexapod Interface Agent after 2 years.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'A Single Dose, Cytomegalovirus-based Vaccine to Induce Heterosubtypic Protective Immunity to Influenza A Virus' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

There are 16 known avian IA virus serotypes, which are further subdivided phylogenetically into group 1 and group 2 viruses. IA 'pandemics' with the possibility for high mortality result from 'antigenic shift' following introduction of a virus with a new hemaglutinnin (HA) serotype into an immunologically naïve population. In contrast, IA 'epidemics' are a consequence of 'antigenic drift' caused by mutation of the HA serotype already circulating within the human population. Seasonal flu vaccines induce antibodies primarily against the globular highly variable head region of HA, and target only a single serotype (homosubtypic immunity). There are currently no commercially available vaccines that are able to induce immunity against multiple IA subtypes and thereby provide heterosubtypic immunity for a pandemic IA vaccine. This CIG project will be run in parallel of a larger collaborative study that is under review at the BBSRC focused on antibody (Ab)-mediated protection. The primary aim of this CIG proposal is to investigate the role of T cell responses (and particularly ‘effector’ T cell memory TEM responses that have immediate effector function and are enriched in lung tissue) in providing protection against pandemic flu.  To enable the role of TEM in IA protective immunity to be assessed we will compare the protective efficacy of T cell immune responses induced against IA nucleoprotein (NP) by using 2 distinct vaccine vector platforms that differ in their induction of TEM responses. This is an area of flu vaccine development that has been largely overlooked. By running alongside the larger BBSRC study, this CIG project will take advantage of the infrastructure provided by the BBSRC proposal. The strategic goal of all these studies is development of  an effective, safe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Impact of vector-mediated transmission on the evolution and ecology of a bee virus' to be submitted under Horizon 2020.

assistant: **Abstract**

The emergence of novel transmission routes is likely to have profound impacts on the ecology and evolution of infectious diseases, with potentially dramatic effects on host populations. This might be particularly drastic when transmission changes from direct to vector-borne transmission, where prevalence and virulence are expected to increase. Despite its importance for disease control, we lack empirical and theoretical understanding of this process. The emergence of Varroa destructor in honeybees provides a unique opportunity to study how a novel vector affects pathogen ecology and evolution: this ectoparasitic mite is a novel vector for Deformed Wing Virus (DWV), a disease linked to severe increases in hive mortality. To study the fundamental evolutionary ecology of emerging vector-borne diseases, I will exploit a unique natural experiment, the presence of Varroa-free island refugia, to test how this novel vector affects epidemiology and evolution in the field. I will adapt cutting-edge single molecule sequencing to guide  controlled lab experiments by viral evolution in the wild, establishing novel reverse genetics approaches in DWV to test causal links between phenotypic and molecular evolution. Like all emerging diseases, DWV is a multi-host pathogen that also infects wild bee species not infested by Varroa, such as bumblebees. This raises an additional question, highly relevant for zoonotic diseases: does this specialist honeybee vector impact disease in wild bee populations? I will model the impact of vector acquisition and evolving pathogens on host populations and test potential prevention and mitigation strategies to safeguard these crucial pollinators. This system will not only provide fundamental insights into the evolutionary ecology of disease, but is also
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Processes water management and optimisation by the re-use and recuperation of textile finishing baths' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Textile finishing is an intensive water consumption activity and also an important pollution source. The process water is used for preparation bleaching and dyeing baths. It 's usually used for the washing processes. The washing commonly known as rinsing represents more than 75% of total water consumption. It's expected that by proper management of rinsing operations saving of more 30% of water consumption may be obtained in dyeing machines. European textile finishing consume annually 128 million m3 of water and generates very important a waste water. A best management and optimisation of rinsing will allow to save 38,3 million m of water per year in Europe. But it is possible to obtain best results with the re use and recuperation of residual bleaching and dyeing baths. Three main industrial objectives are foreseen in this project: - optimising rinsing operations, - Re using of rinsing waste water or processes baths - Recuperation of residual baths after a specific treatment baths Two main technical objectives are: - development of mathematics model in order to optimise rinsing operations, - definition of experiment plans and experiments in order to re-using or recuperation the waste water. It provides a new way of rinsing management by using measuring equipment which may be integrated in the computer aided control panel. Rinsing will be stopped at the moment when anyone water would be more effective. Less or strong contaminated water will be selected with help of appropriated sensors and diverted to storing tank from which is re used (so that less fresh water will be requested) or treated by ultra filtration or nano filtration. The partnership to carry out this project is an effective conjugation of environmental competencies between the R&D performers and industrial
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Stable and Clean Iron Power from ICONIC' (ICONIC) targeting Horizon Europe.

assistant: **Abstract**

Iron Power is a new technology to store and transport sustainable energy. An iron aerosol mixture is burned in a flame and the heat is used in high temperature processes. The formed iron-oxide powder is collected and transported to places with a surplus of green hydrogen, where it is regenerated back to iron powder. As such, Iron Power is  a very promising CO2-free circular energy carrier of sustainable energy, which has a very high energy density, is easy to handle, safe, environmentally friendly and cheap. Within the fast growing Iron Power community, existing solid fuel combustion concepts are applied mostly, but these show severe problems caused by the specific character of iron aerosol flames: a) flame stabilisation is difficult to establish, b) nano-particles and c) high NOx emissions are also difficult to circumvent. A completely new combustion concept is needed to solve the problems. The ERC program MetalFuel creates the basic knowledge on metal aerosol combustion with the right ingredients to do solve these problems. The combustion concept developed is called ICONIC (Ignition COntrolled  low-Nox Iron Combustion). Within this ERC PoC a well-controllable ICONIC burner will be developed, designed, tested and patented. A small-scale system will be developed and studied first, after which a conceptual design of Mega-Watt size will be developed which will enable future implementation in an industrial-scale system. Furthermore, the possible future market will be evaluated. A start-up is already interested and a launching customer seems to be in view, if the PoC is successful.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Development of a Combined Synchrotron Radiation and VUV Free-Electron Laser Facility', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

* Implement a free-electron laser (FEL) on the ELETTRA storage ring to produce a source of intense, highly monochromatic, tuneable, spatially coherent radiation.* Optimise the FEL performance to enable a wide wavelength range to be covered, at least between 350 and 190 nm.* Demonstrate that the FEL can be operated while still permitting the operation of other synchrotron radiation beamlines.* Carry out pilot experiments with the FEL beam to demonstrate its potential use.Expected deliverables.* Design, construction and testing of the optical cavity unit (task A).* Production and testing of mirrors (task B).* Design, construction and testing of undulator and front-end (task C).* Characterization of electron beam properties (task D).* Theoretical prediction of FEL performance (task E).* Commissioning of the FEL (task F).* Execution of proof-of-principle experiments (task G).The main activity highlights have been:* Feb. 29th, 2000: First lasing at 350 nm.* May 27th 2000: Lasing at 220 nm.* Sep. 17th 2000: Wide tunability of 30 nm demonstrated around 250 nm.* Nov. 17th 2000: 180 mW extracted power at 250 nm * Feb. 6th 2001: Lasing at 190 nm - a world record for the shortest wavelength of a FEL oscillator.In addition, the first pilot experiments have been carried out using the FEL radiation and one other undulator beamline has successfully operated in parallel with FEL operation. The main objectives of the project have therefore substantially been met. More specifically:Mirror Chambers: Two sophisticated UHV mirror chambers, each containing up to 3 mirrors that can be remotely interchanged and accurately positioned, were designed and constructed at CLRC-Daresbury Laboratory. Each unit contains 8 drive systems for x, y, z positioning, mirror change, and coarse (stepping motor)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'New Energy Externalities Development for Sustainability' (NEEDS) targeting Sixth Framework.

assistant: **Abstract**

The NEEDS proposal addresses Priority 6.1: Sustainable Energy Systems and, more specifically, Sub-priority 6.1.3.2.5: Socio-economic tools and concepts for energy strategy. Its ultimate objective is to evaluate the full costs and benefits (i.e. direct + external) of energy policies and of future energy systems, both for individual countries and for the enlarged EU as a whole.Major advancements will be achieved in the three main areas of:-Life Cycle Assessment (LCA) of energy technologies-monetary valuation of externalities from energy production, transport, conversion and use-integration of LCA and externalities information into policy formulation and scenario building.The NEEDS IP is built as a series of research streams ":1a) LCA of new energy technologies1b) New and improved methods to estimate the external costs of energy conversion1c) Externalities associated to the extraction and transport of energy1d) Extension of the geographical coverage of the current knowledge of energy externalities2a) Modelling internalisation strategies, including scenario building2b) Energy Technology Roadmap and Stakeholder Perspectives3a) Transferability and generalisation3b) Dissemination/communicationA dedicated Integration Stream will deal with all interlink ages between streams.The consortium includes 80 partners (of which over 20% are SMEs), representing 30 Countries (13 EU Member States, 10 NAS, 3 Mediterranean Countries, and 4 Countries from other parts of the World), and a balanced mix of Universities, Research Institutions, Industry, NGOs.Most leading institutions in the area of energy externalities research are represented.The Consortium is coordinated by ISIS, Institute for System Integration Studies (Rome)Over the 4-year duration of the IP, the resources mobilised amount to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The control, identification and delivery of prescribed medication' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The problems associated with non-compliance to a prescribed medication regime can have serious implications for the health of the patient and incur unnecessary healthcare costs. It is the aim of the proposed project to investigate the needs of such patients, analyse current methods used to address this problem and develop an innovative care model and associated peripherals to assist with compliance to a medication regimen. The infrastructure of the care model will be centred on an Internet-based control server, providing remote monitoring and control of the patient's regimen. Hardware will be developed for home use, to store the medication, dispense it appropriately and provide a reminder to the patient in cases of non-compliance. A clinical evaluation is proposed to ascertain the potential success in reducing non-compliance by 5-7%.DESCRIPTION OF WORKThis project entails the development of a medical device and associated care model aimed at the delivery and dispensing of drugs. The device is connected to a dedicated control centre, to which doctors, pharmacists and other registered professionals have access, via a communications network, and thus allows the development of a comprehensive care model.Implementation of the project involves 5 stages and the main tasks to be undertaken are:a human factor analysis to appreciate the needs of the user and all other stakeholders;review the current methodologies employed to assist with non-compliance and the process of Telecare;develop the MEDICATE care model and its associated peripherals;gain levels of user acceptance from analysis of prototypes and the final model;integrate the proposed care model into existing home care scenarios within the target groups;undertake a series of clinical evaluations to produce a scientific anal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Computing Answers to Complex Questions in Broad Domains'.

assistant: **Objectives**

The explosion of information around us has democratized knowledge and transformed its availability forpeople around the world. Still, since information is mediated through automated systems, access is boundedby their ability to understand language.Consider an economist asking “What fraction of the top-5 growing countries last year raised their co2 emission?”.While the required information is available, answering such complex questions automatically isnot possible. Current question answering systems can answer simple questions in broad domains, or complexquestions in narrow domains. However, broad and complex questions are beyond the reach of state-of-the-art.This is because systems are unable to decompose questions into their parts, and find the relevant informationin multiple sources. Further, as answering such questions is hard for people, collecting large datasets to trainsuch models is prohibitive.In this proposal I ask: Can computers answer broad and complex questions that require reasoning overmultiple modalities? I argue that by synthesizing the advantages of symbolic and distributed representationsthe answer will be “yes”. My thesis is that symbolic representations are suitable for meaning composition, asthey provide interpretability, coverage, and modularity. Complementarily, distributed representations (learnedby neural nets) excel at capturing the fuzziness of language. I propose a framework where complex questionsare symbolically decomposed into sub-questions, each is answered with a neural network, and the final answeris computed from all gathered information.This research tackles foundational questions in language understanding. What is the right representationfor reasoning in language? Can models learn to perform complex actions in the face of paucity of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Structural dynamics of acyl carrier protein complexes through combined solution and solid-state NMR'.

assistant: **Concept**

Antibiotics are a vital part of modern medicine. However, the available arsenal of antibiotics becomes less effective as microorganisms develop ""resistance"" against them. The resulting crisis in medicine necessitates development of new drugs. Natural products inspired compounds are a potential solution to this challenge. For example, gladiolin biosythesized by a mulitenzyme polyketide synthase (PKS) was shown to be active against Mycobacterium tuberculosis, a multidrug resistant bacterium that one third of world’s population is infected with. The PKS producing gladiolinum is a good example of multienzymatic assembly lines that due to their modular nature are ideal for genetic manipulation paving the way for synthetic biology approach to produce new drugs (that are difficult to synthesize using chemical methods). However, for such approach to be successful it is crucial to understand molecular level structural and dynamical factors responsible for controlling directionality and specificity of biosynthesis. Neglecting such factors, when modifying PKSs often results in assembly lines that are inactive or dysfunctional. Here we propose to use a novel approach combining state-of-the-art solution and solid-state NMR methods to investigate structure, dynamics and interactions of proteins from module 12 of gladiolin PKS, particularly acyl carrier proteins (ACP12a and ACP12b) and special adapter ketosynthase (KS12), all of them highly required in industrial biosynthesis toolbox. We will use solution NMR to characterize isolated ACPs and solid-state NMR to study ACPs-KS12 complexes (direct structural information is difficult to obtain by solution NMR due to the large complex size). Combining solution and solid-state NMR relaxation methods will allow us to probe protein motions