RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Citizenship after Orientalism' in the context of a Seventh Framework call.

assistant: **Objectives**

This project focuses on the interaction between two controversial and contested concepts: citizenship the process by which belonging is recognised and enacted and orientalism the assertion of the superiority by western culture over its eastern counterparts. It is a critique of the argument that explains the success of European capitalism in terms of differences in social structures that had effectively prevented the emergence of citizens in oriental societies. The ambitious scope of this project is to revisit questions of citizenship in orientalized cultures India, China, Islam and Indigenous through investigations untrammelled by orientalist assumptions. The research methodology is genealogical through which the origins, interpretations and mutations of ideas and actions will be clearly located in their historical and cultural settings. The project methodology is designed deliberately to focus on disagreements. Rather than working with like-minded collaborators, the project will engage with its antagonists through a series of workshops where opposing views will be debated and disseminated to a wide audience. What it means to be a citizen, who may be a citizen, what obligations derive from citizenship are at the forefront of much political discourse as the nation-state dissolves into regional identities, integrates or fails to integrate new social groups, and is transformed by supra-national entities. Above all, the question of citizenship lies at the heart of the legitimacy of the European Union. Yet, when we investigate the origins of ideas about (European) citizenship we discover that it is essentially considered as a Judeo-Christian development juxtaposed against Buddhism, Confucianism, Islam, and Hinduism. The project will contribute to investigating genealogies of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Major transitions made easy? In search of genetic preconditions that help the repeated evolution and loss of fungal multicellularity' (CONVERGENCE).

assistant: **Concept**

In this project, we aim to study the genetic mechanisms of convergent evolution by uncovering the mechanistic details of two highly replicated transitions in organismal complexity. Convergent evolution is widespread in nature, even on macroevolutionary timescales. To explain its pervasiveness, recent studies have proposed the idea of predisposing precursor traits that, if easily co- or exapted for new functions, can increase the likelihood of convergence. However, most of these hypotheses remain untested because of the lack of tractable model systems. We identified two fungal case studies that offer optimal model systems to mechanistically test the hypothesis that precursor traits increase the likelihood of convergence: (i) 8-11 repeated origins of complex multicellularity in mushrooms and (ii) >14 losses of multicellularity in yeast-like fungi. We hypothesize that both of these occurred by the repeated exaptation of ancient morphogenetic programs and, in the case of yeasts, additionally, by the emergence of mechanisms for bypassing multicellular growth. Our hypotheses imply that both complex multicellular and yeast-like lifestyles are only a few mutations away for any filamentous fungus because precursor traits shorten the mutational path for evolution. Although these are bold hypotheses, we obtained promising preliminary results that support them. We designed an experimental plan involving phylogeny-aware comparative -omics, reverse genetics, and evo-devo, which, when combined with our preliminary results, will provide a robust entry point for testing the role of predisposition in convergent evolution and will ultimately allow us to “replay the tape of major fungal transitions” in the laboratory. We expect this project to contribute to uncovering the general principle
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'DIgital DYnaMic and respOnsible twinS for XR' in the context of a Horizon Europe call.

assistant: **Objectives**

The digital transformation and the availability of more diverse and cost-effective methods for 3D capture has led to the creation of digitised representations of parts of our public spaces, machinery and processes, so-called Digital Twins. These Digital Twins are an important basis for building advanced XR applications for cityscapes and the industrial environments. These XR applications need high-fidelity models for accurate localization, which are kept in-sync with the real world. However, currently (i) creating high-fidelity Digital Twins is costly, (ii) integrating data from heterogeneous sensors is still challenging and (iii) the update of Digital Twins requires explicit manual intervention.The vision of DIDYMOS-XR is to enable advanced, more realistic and more dynamic extended reality (XR) applications, powered through artificial intelligence. The project thus focuses on advancing technologies for creating large-scale digital twins, synchronised with the real world. DIDYMOS-XR will research and develop methods for reconstruction and mapping from heterogeneous inputs, including static and mobile sensors, AI-based data fusion, scene understanding and rendering. Digtal twin based XR applications also require means of accurately positioning in the environment, aware of the dynamics of the scene, also addresed by the project.The capture of scenes at scale, as well as using cameras and other sensor data for synchronising the digital representation, bears the risk of capturing personal and sensitive data. Hence, the technologies resulting from DIDYMOS-XR must be and will be ethical and privacy-aware by design.In order to demonstrate and validate the enabling technologies researched and developed in DIDYMOS-XR, the project will address use cases of XR applications in two
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'SELF-ORGANIZED NANOMATERIALS FOR TAILORED OPTICAL AND ELECTRICAL PROPERTIES' in the context of a Seventh Framework call.

assistant: **Objectives**

The NANOGOLD project aims at the fabrication and application of bulk electro-magnetic metamaterials. A promising new concept for the exploration of metamaterials is the use of periodic structures with periods considerably shorter than the wavelength of the operating electromagnetic radiation This concept allows to control the refractive properties. Making use of a bottom up approach in materials design, we will apply self-organization of organic-inorganic composite materials containing resonant entities. To tune electromagnetic properties, resonance and interference at different length scales will be implemented. In such a way we will obtain bulk optical metamaterials operating in spectral domains appropriate for photonics that can be used in applications.  Our groundbreaking solution to form such artificial matter is interdisciplinary and combines inorganic chemistry, organic macromolecular synthesis, physics of electromagnetic resonances and liquid crystal technology. We start with resonant entities (metallic nanoparticles) and organize them via self-organization on the molecular scale. Systematic modular variation of the chemical entities gives access to libraries of materials which will be used to arrive at systems with desired properties. Simulation of optical properties and molecular ordering will guide the design of compounds and materials. Organization at molecular level leads to homogenous materials with optical, electronic or magnetic properties at elevated frequencies, in the visible and near infrared spectral range. The controlled utilization of the polymer physics of micro-segration, will allow for additional structuration at the nano-scale giving design freedoms to tune material properties optimally. NANOGOLD furthermore will make use of innovative fabrica
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Flavonoids in fruits and vegetables : their impact on food quality, nutrition and human health' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

The overall objective of the project is to provide the necessary knowledge, tools and validatedmethods to enable development of high quality, consumer-acceptable fruits and vegetables (F&V) andderived foods / beverages containing flavonoids at levels that are optimal for human health.The study will mainly focus on proanthocyanidins (PAs) because, unlike other flavonoids, there isconsistent evidence, from short-term clinical trials, supporting a role for PA in maintainingcardiovascular function and decreasing CVD risk. Such clinical studies have used PA-rich extractsincluding pine bark, grapeseed, cocoa and 'American' fruit juices (cranberry, blueberry, purple grape)that are sold in low volumes in Europe. The flavonoid / PA rich plants and products used in the project(i.e. grape, apple, strawberry, broccoli, and tomato, juices, wine and cider) are suitable candidates todevelop European plant-based foods with improved flavonoid content and can have a broad impact onboth citizen health and SMEs. This knowledge, combined with recent advances in our understanding of, and ability to specifically alter, plant flavonoid biosynthesis and food/beverage content, will beexploited to develop F&V with altered PA composition as health-promoting food products. The specific aims follow a Fork to Farm" approach to: (1 ) Determine the optimal source and dose of PAs for conferring health benefits while avoidingpotential risks (2) To develop analytical tools for selecting raw materials and transformation processes for modifying PA composition in order to ensure optimal quality of plant-derived foods and beverages (3) Provide biotechnological tools for producing F&V with an optimised PA composition, and (4) Study consumer attitudes towards the processes used and products derived from the app
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Smart Tall Buildings by using Piezoelectricity in Joints' under Horizon 2020.

assistant: **Concept**

The SMART-UP project will initiate innovative devices called piezoelectric-dampers (PiDs) to be embedded in modern tall buildings for simultaneous structural elements connection and energy harvesting (EH). PiDs are composite elements (piezoelectric+steel or rubber) located in the connections between buildings’ structural members and engaged by wind-induced oscillations to transform the kinetic energy of the oscillating structure into electricity. The concept of PiD is transformative as this will scale-up currently developed piezoelectric EH (pzEH) techniques at the micro and meso-scales to the truly macro scale. pzEH devices have never been implemented as structural connections in civil buildings for a number of reasons, such as the inadequacy of piezo materials in carrying loads and low frequencies of the vibrations occurring in buildings. These will be comprehensively addressed in SMART-UP by innovative in-parallel coupling schemes between piezo and the load-carrying members such as steel and/or rubber and by allowing the piezo-blocks working in nonlinear regimes arising from buckling or impact. These features will allow their implementation in buildings for powering wireless sensors provided for building automation, which leads to an increment of the building sustainability, and for structural-health monitoring, leading to an increase of the building resilience. Thanks to the introduction of these novel macroscale EH skills, the SMART-UP project makes a step-change in high-rise buildings design and management, by defining a new breed of tall SMART buildings with self-powering, adaptive-in-behavior capabilities. The envisioned buildings not only resist wind loads, but they exploit wind-induced vibrations to reduce their carbon footprint and improve their performances.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'EUChinaGRID: Interconnection and Interoperabilty of grids between Europe and China' (EUCHINAGRID).

assistant: **Concept**

EUChinaGRID Project aims to support the interoperability of the Grid infrastructures in Europe and China for the benefit of eScience applications. A second important goal is the dissemination and training activity, which aims to improve the accessibility of the Grid infrastructure for new applications and promote scientific and, possibly, industrial developments.The main motivation of EUChinaGRID is to facilitate exchange and processing of scientific data supporting a pilot interoperable usage of the most relevant Grid Infrastructures in Europe (EGEE) and in China (CNGrid). A proof-of-principle approach for validating applications used by existing collaborations between Europe and China has also been identified. Those research activities are involving intercontinental scientific communities that have strong requirements for analysis of large quantities of data and of large amounts of computing power. The project will study and support the extension of a pilot intercontinental infrastructure using the EGEE supported applications and will foster the migration of new applications on the Grid infrastructures in Europe and China by training new user communities and support the adoption of powerful grid tools and services.All the selected pilot applications, consequently, will on one hand immediately take advantage of these new infrastructures, and on the other hand be the driving force to promote the interoperability of grid infrastructures between Europe and China.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Development of a integrated system for livestock extensive exploitation.' in the context of a Fifth Framework call.

assistant: **Objectives**

The Objective of this proposal is to establish the scientific base of the possible problems which may arise in the development of an Integrated Extensive Breeding System which has not been standardised yes in the countries of the E.U., regions in order to obtain high quality, healthy products derived from pigs bred at large taking advantage of stubble from biological cultivation, pastures and other agricultural and forest fruit. This research will study the conditions and will define the following parameters; technological, genetic. Economic, environmental, nourishing, sanitary and animal welfare.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Molecular Oncology Early Research Training'.

assistant: **Innovation**

The aim of this proposal is to provide interdisciplinary training for early stage researchers in state-of-the-art molecular oncology. The recent growth of proteomics, genomics and other large-scale approaches has generated an enormous wealth of data that has transformed cancer research. Current cancer research is thus a multidisciplinary field of research involving disciplines such as biology, medicine, computer sciences, physics and chemistry, for example. However, the new strategies and experimental technologies not only have generated a stream of novel data, but in addition they have created an unprecedented demand for scientists with ample cross-disciplinary training in the various fields involved in cancer research. Addressing this urgent demand, the ONCO-TRAIN programme has the strategic objective to offer a comprehensive and highly multidisciplinary training programme in molecular oncology. Eight 3-year fellowships will be offered to perform Ph.D. studies in molecular pathology, molecular oncology, structural biology, experimental therapeutics and biotechnology. The research training is accompanied by complementary training designed to the needs of early stage researchers with the aim to strengthen the development of additional skills and to widen their career development prospects. This comprehensive and integrative training programme will contribute to the creation of a new European cadre of molecular cancer researchers with technical excellence, originality and breadth of vision.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Training Network for the Development of Bacterial ExoPolysaccharides for the treatment of Inflammatory Conditions' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The essence of this proposal is to establish a collaborative training network which will develop novel immune-regulatory molecules from Bifidobacterium infantis 35624, for treatment of inflammatory diseases. A multidisciplinary team of four prestigious European partners has been assembled (SME & Coordinator - Alimentary Health Ltd (expert in developing probiotic products); Swiss Institute for Asthma and Allergy Research, (expert in immune-regulation); Vienna Institute of Biotechnology at Universität für Bodenkultur (expert in glycobiology); and University College Cork, Alimentary Pharmabiotics Centre and Department of Microbiology (expert in bioinformatics and glycobiology assembly in probiotic bacteria). Each partner will provide unique critical expertise, through knowledge, personnel and facilities which will be complementary and additive and will provide the synergistic expertise required to successfully deliver on the goal of this project and forge a long-lasting relationship. The end result: a unique opportunity for cross-sector state-of-the-art knowledge transfer and dissemination, through the identification of molecules from B. infantis 35624 with proven efficacy in the treatment of IBS and other inflammatory conditions – expected to have major commercialization, economic and health implications.B. infantis 35624 is a commensal micro-organism, originally isolated from human gastrointestinal tissue, which has demonstrated unique properties in human clinical studies. B. infantis 35624 consumption is associated with significant improvement in the composite score for abdominal pain/discomfort, bloating/distention, and/or bowel movement difficulty compared with placebo in two appropriately designed studies. No other bacterial strain has shown significant improvement i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Light-activatable ruthenium-based anticancer prodrugs'.

assistant: **Concept**

Chemotherapy is, after surgery, the second most efficient therapy against cancer. However, it has many side effects for cancer patients because anticancer drugs kill cancer cells but also healthy ones. My project aims at synthesizing new metal-containing compounds that 1) are poorly toxic in the dark; 2) can be attached via a light-sensitive bond to liposomes that will carry them into cancer cells; and 3) detach from their carriers and become toxic upon light irradiation, thus killing cancer cells.These new compounds contain ruthenium, a metal combining photochemical and anticancer properties. I will replace the weakly bound chloride ligands of known cytotoxic ruthenium compounds by strongly bound sulfur ligands. By doing so, the DNA- and protein-binding ability of the ruthenium compounds will be lowered, which will lower their toxicity in the dark. Thioether-lipid conjugates will be used to attach the ruthenium prodrugs to liposomes carriers that are well taken up by cancer cells.Techniques to irradiate tumors in vivo are nowadays available in the clinics. By shining light onto the ruthenium-enriched cancer cells photochemical cleavage of the Ru-S bond will take place, thus detaching the metal complex from its carrier and allowing it for binding to biological molecules. Thus, the ruthenium prodrug will be transformed inside cancer cells into a highly toxic molecule that will kill the cells. I will study mononuclear compounds and molecules containing several ruthenium centres; visible light activation and near infrared light activation. The final aim is to obtain ruthenium-functionalized liposomes that are poorly toxic in the dark, preferentially go into cancer cells, and become toxic at the place of irradiation, using light that penetrates well into biological tissues.