RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Tempo-spatial stochastic volatility: Modelling and statistical inference' (TSSV), addressing dissemination and exploitation.

assistant: **Impact**

Statistics for tempo-spatial data is one of the most important research frontiers in modern statistics. This project proposes to introduce and develop the concept of tempo-spatial stochastic volatility, which allows one to model volatility clusters both in time and in space.  Empirical evidence for stochastic volatility is ubiquitous, and hence, it is vital and urgent that statistical models and estimation methods will be developed to account for this key quantity.Stochastic volatility is a latent variable, meaning that it is not directly observable but needs to be estimated from other (observable) variables. The main research objectives are to construct novel, non-parametric estimators for tempo-spatial stochastic volatility and to establish the corresponding asymptotic theory for constructing confidence regions. Moreover, fully parametric classes of stochastic volatility models will be developed, and the corresponding statistical inference techniques will be derived.The objectives will be achieved by developing the concept of realised quadratic variation for random fields, which results in a non-parametric proxy for tempo-spatial stochastic volatility.  Also, novel, parametric estimation procedures will be designed to estimate the parameters of new tempo-spatial stochastic volatility models based on a quasi-maximum-likelihood framework.The completion of this project will be a major breakthrough in statistics and will solidify Europe’s leadership in this field. Moreover, it is of key relevance to the Work Programme since it strongly contributes to the initiative “sustainable growth”: The results of this research project are directly applicable to, e.g. measuring and modelling the risk associated with climate change and to finding an optimal design for wind farms, makin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Renewable and Waste heat valorisation in Industries via Technologies for Cooling production and energy Harvesting', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The overarching aim of RE-WITCH is to deliver cost-competitive, game-changing solutions in the field of sustainable industrial cooling and heating. To do so, RE-WITCH will demonstrate advanced thermally-driven industrial cooling technologies based on ADsorption and ABsorption processes driven by an optimized mix of low-grade waste and renewable sources (innovative high vacuum flat plate solar collectors). Such solutions will be demonstrated in 4 demo sites encompassing food and beverage sectors as well as industrial sectors where heat-to-cold solutions are not yet widely explored (bio-refinery, pulp & paper). The activity will be completed by studying the replicability of proposed technologies in replication sites even integrated with DHN. The project will be delivered by an industrial-driven consortium of 26 partners from 10 countries and it is composed by some of the most innovative SMEs, LEs and R&D centers in the field of industrial renewable H&C leveraging experience from industrial and EU-funded projects (HYCOOL, SO-WHAT, Indus3Es). The multi-disciplinary composition of the consortium ensures that all the challenges (technical and non-) will be addressed to ultimately bring RE-WITCH solutions to the market by 2029. Innovative open access modelling platforms and engineering solutions will be also developed to facilitate the design, upscale, replication and integration in industrial processes of the proposed technologies. Thanks to a stakeholders’ driven dissemination and communication campaign, RE-WITCH will ultimately demonstrate transformative technological solutions that unlock the combined potential of low-grade waste and renewable heat use in industries, hence also targeting integration of heat-to-cold technologies into relevant EU Policies.


**Keywords:** ab
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Evolution of Dust in Turbulent Protoplanetary Disks' (EDIT) targeting Seventh Framework.

assistant: **Abstract**

Protoplanetary disks (PPDs) are the birthplace of planets like our Earth. In recent years hundreds of planetary systems have been detected, where some planets appear to be in the habitable zone and show best conditions to retain water, a prerequisite for life. So far the formation of planets and planetary systems is not totally understood. It is known that planet formation takes place in PPDs and that dust particles are the basic modules for planet construction. With the growth of dust grains, which have their origin in the interstellar medium, planet formation starts. To study these first steps of dust growth, which are closely coupled to the dynamics in the disk, is therefore of relevance to understanding planet formation and the origin of life.Studying the dynamical effects of dust in PPDs is so far based on simple dust models, which fail in many aspects to explain observations and planet formation. The need to include a realistic dust model is expressed in many studies. In collaboration with researchers at Queen Mary University, I have developed a science program which together will allow us to address the key questions of the influence of the dust properties on the spatial distribution, the dust evolution and on the planet formation processes in turbulent PPDs. In the interstellar medium, single dust grains are of core-mantle composition which coagulate into aggregates in dense regions. Implemented in PPDs, these aggregates undergo evolutionary processes which are influenced by turbulence in the disks. In PPDs, ionised gas is magneto-hydrodynamic turbulent due to magneto-rotational instabilities. The gas drag affects the dynamical behaviour of dust which is strongly dependent on the grain properties. The results of my model calculations which consider realistic agg
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Combining Optics and SDN In next Generation data centre Networks'.

assistant: **Concept**

The role of Data Centres (DCs) is vital for the Future Internet. However, DC infrastructures are already stressed by data volumes and service provisioning and consumption trends. Emerging demands cannot be addressed by today's DCs and call for a massive redesign or even transformation of DC architectures.COSIGN proposes a new DC architecture empowered by advanced optical technologies and will demonstrate novel solutions capable of sustaining the growing resource and operational demands of next generation DC Networks. COSIGN aims to move away from today's vendor specific, manually controlled, performance and scale limited DCs towards scalable DC solutions able to support future-proof dynamic, on-demand, low-latency, energy efficient and ultra-high bandwidth DC solutions. COSIGN introduces disruptive transformations in the data plane, significant advances to the control plane and major innovations in the DC virtualization and service orchestration: In the DC Data Plane, COSIGN will deliver an entirely-optical solution enabling scalable top-of-rack switches, ultra-low latency and high volume DC interconnects with high spatial dimensioning. In the DC Control Plane, COSIGN will build upon and extend the Software Defined Networks (SDN) paradigm leveraging capabilities from high-performance optical technologies while developing technology agnostic protocols for software/user defined routing and control.  For the DC Management and Orchestration, COSIGN will implement a coherent framework for optical network and IT infrastructure abstraction, virtualization and end-to-end service orchestration.COSIGN brings together a unique combination of skills and expertise able to deliver, for the first time, a coordinated hardware and software architecture, which will guarantee the scale
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Programmable Artificial Cell Evolution (PACE)' (PACE), addressing dissemination and exploitation.

assistant: **Impact**

The integrated project PACE will explore the utilization of the simplest technically feasible elementary living units (artificial cells much simpler than current cells) to build evolvable complex information systems. We will create, analyse and investigate the applications of such systems that process information by self-organization starting at molecular scales. We will also determine whether life-like properties are necessary for computational systems to be fully robust and adaptive and investigate the tension between evolvable living autonomy and programmable utilization.We will explore the collective properties of artificial cells and demonstrate that they are the right material for building nanoscale robot ecologies. The particular molecular systems we will consider will have genetically controlled catalytic reactions, self-assembly of complex supra-molecular structures, and energy transduction. We will investigate the stepwise evolution of such complex systems by machine complementation and combinatorial search using a programmable microfluidic interface.We will provide theoretical and simulation frameworks for understanding emergent computational properties of such systems, and experimental frameworks for programming them by evolutionary exploration of chemical reactions. We will integrate and disseminate multidisciplinary European activities to give it a decisive international competitive advantage in this FET.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Advanced Forecast For Ensuring Communications Through Space' (AFFECTS) under Seventh Framework.

assistant: **Objectives**

In this call the EU supports activities strengthening space foundations reducing the vulnerability of space assets from space weather events. Solar activity affects the entire Earth environment from the magnetosphere down to the ionosphere and even to the lower atmosphere climate system. The natural hazards of space weather do not only modify the atmosphere but also can catastrophically disrupt the operations of many technological systems, thus causing disruption to people's lives and jobs. The AFFECTS collaborative project uniquely addresses these key topics through state of the art analysis and modeling of the Sun-Earth Chain of Effects on the Earth's ionosphere and their subsequent impacts on communication systems. Multipoint space observations enable world-leading experts at the highest level of interdisciplinary excellence to forecast the relevant space weather effects on the ionosphere quantitatively. The unique set of measurements from satellites in different orbits is complemented by dedicated ground-based monitoring of auroral electrojet and ionospheric activity. The AFFECTS team consists of key European space weather research teams and the US Space Weather Prediction Center of NOAA. To date no dedicated space weather forecast system for ionospheric applications exists in an operational manner, and thus this project would lead to an entirely new capability in Europe that is not only important for society but also does not exist elsewhere. AFFECTS is an unprecedented project which in time of the expected next solar maximum around 2012 will provide advanced prediction, assessment and early warning capabilities of disruptive space weather events that are expected to be particularly poignant to society and thereby meets the needs of Europe’s community of users. AFF
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Protein citrullination as a link between periodontal diseases and rheumatoid arthritis (RA) and target for development of novel drugs to treat RA' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Autoimmunity in rheumatoid arthritis (RA) is characterised by an antibody response to citrullinated proteins. Periodontitis (PD) is largely caused by infection, in whichPorphyromonas gingivalis is a major pathogen. The two diseases combine specific HLA-DRB1alleles and smoking as risk factors, and have a similar pathophysiology characterised by destructive inflammation. A possible causative link between RA and PD is based on the ability of P. gingivalis to citrullinate proteins and thereby generate autoantigens that drive autoimmunity in RA. We hypothesise that anti-citrullinated protein antibodies can be generated, in genetically susceptible individuals, as a consequence of P. Gingivalis-induced citrullination in the gingiva. In the context of genetic risk factors, during chronic exposure to danger signals, such as bacteriallipopolysacharides and DNA, tolerance to citrullinated proteins may be broken, with production of a pathogenic antibody response, which at a later time point cross-reacts with joint proteins and causes chronic RA. We will use a multidisciplinary approach (genetics, epidemiology, molecular immunology and animal models) to study susceptibility factors and immune responses in RA and PD, with an aim to identify novel etiological and pathogenic pathways, forming the basis for new therapies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Non-replicating particles as immunogen carrier' (1998-2002).

assistant: **Concept**

To employ two non-replicating delivery systems will be employed to deliver antigens to the immune system and to elicit the appropriate protective immune responses against human diseases such as HIV, HCV and tumours. The immune responses and their protective efficacy will be assessed in animal models. The mechanism of CTL activities of these particles and their ability to induce mucosal responses will be studied. Both particles will be further investigated and modified for broader application.Brief descriptionTwo different self-assembled structures that lack nucleic acid have been developed as immunogen delivery systems during previous EEC funded projects. These are PPV-VLPs and NS1-TUBs and both have been shown to be highly immunogenic. Based on previous data we propose to generate chimeric VLPs and TUBs carrying a selection of T-cell epitopes of HIV-1, HCV and tumour antigens using recombinant baculovirus expression systems and insect cell cultures. Each assembled chimeric particles will be purified and characterised thoroughly at molecular and antigenic levels. Subsequently, these particles will be utilised to investigate their immunogenicity and their capabilities of inducing the appropriate immune responses in in vitro and in vivo model animals. The protective efficacy of each chimeric construct will be further assessed by challenge experiments in pre-clinical studies and for some constructs in clinical studies, if the opportunity becomes available. CTL response by non-replicating particles is a novel approach, and therefore the mechanism of such activity will be investigated in depth using the appropriate constructs. Lastly, each of the delivery systems will be modified by creating additional foreign sequence sites generating multiple chimeric copies by single reco
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Algorithms for Complex Shapes with certified topology and numerics' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Increasingly demanding applications of geometric computing, for example in computer aided surgery, CAD/CAM, realistic virtual environments, robotics, and molecular modelling in drug design and structural biology, require efficient and robust methods for computing with complex shapes. This project aims at advancing the state of the art in this field. Current technology can cope well with curves in the plane and smooth surfaces in three-dimensional space. We want to deal with a larger class of shapes, including piecewise smooth and singular surfaces. Topics that we address are shape approximation (including meshing and simplification), shape learning (including reconstruction and feature extraction), as well as robust modeling (including boolean operations). Our work on these topics will be closely intertwined with basic research on shape representations, certified geometric calculus and algorithms producing output with guaranteed topology. A distinctive feature is the design and implementation of novel algorithmic solutions with certified topology and numerics as an alternative for heuristics and ad hoc methods, and to develop an experimental geometry kernel for modeling and computing with complex shapes as a proof-of-concept justifying our approach. The results of this project should be directly useful to the application areas mentioned above. We intend to disseminate our work by publication in the appropriate applied research forums, by organizing multidisciplinary workshops aimed at exchange of knowledge and discussion of our work. Moreover, we aim at transferring our new technology by producing high quality software, demonstrating the feasibility of our techniques in practice. Cooperation with our industrial partner includes the assessment, trial, validation and pack
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Super-resolution genomic mapping for the microbiome' (METAMAPPER), addressing dissemination and exploitation.

assistant: **Impact**

Animals and bacteria have been working together for about as long as they have co-existed, long before the advent of mankind. The bodies of our ancient ancestors offered protected, nutrient-rich habitats for bacteria. In return, animals could take an evolutionary short-cut to developing new capabilities by ‘borrowing’ bacterial genes. Indeed, when gut bacteria assist with the digestion of e.g. dietary fiber, the resulting metabolites will subsequently exert an influence on an intricate network of host molecular pathways. Gut microbiota, in addition to host genetics, can therefore constitute a major factor in the etiology of complex disorders, ranging from obesity, cardiovascular disease, autoimmune disease (multiple sclerosis, rheumatoid arthrosis), inflammation (inflammatory bowel disease, Crohn’s) to neurological conditions. Although such a key role for the human microbiomes had been postulated for some time, many details on the delicate interplay between flora and host remained unknown, largely because suitable methods for uncovering these host-guest interactions were simply not available. These technological barriers keep the diagnostic and therapeutic potential of the microbiome largely untapped. In this project, we will validate the FLUROCODE genomic mapping technology as an alternative to shotgun sequencing and amplicon based techniques for microbiome studies. This will extend the benefits of genomic mapping techniques to complex sample analysis. Through a head-to-head comparison with the state of the art in metagenomic analysis, the POC data will serve as a key enabler for the transfer of the technology platform into a separate venture, working towards diagnostic applications and developing METAMAPPER based microbiome screening as a routine medical tool.  The ME