RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'INCOming MARSEILLE22' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

The aim of this project is to organise the Marseille Conference for International Cooperation (#INCO) under the upcoming French Presidency of the Council of the European Union during the first semester of 2022. This two-day Marseille Ministerial Conference being held on the 8th and 9th of March 2022, is an ambitious initiative to promote a Global Approach for Research and Innovation. The event aims at fostering exchanges and good practices setting off a new cooperation framework with partners based on the European Union’s values and objectives. This one of a kind initiative will encourage Europe’s Global Approach towards Research and Innovation. This CSA, will be managed by IRD (French National Research Institute for Sustainable Development) and will contribute to the success of the Marseille Conference which shall involve delegates, both European and International, along with selected external experts. As monobeneficiary of the grant, IRD will liaise with the MESRI (The French Ministry of Higher Education, Research and Education) and the MEAE (The French Ministry of Europe and Foreign Affairs) for the overall organisation of the Conference, . These two days shall be hosted across two different venues – The famous Palais du Pharo Conference centre and the MuCEM museum premises (Musée des Civilisations, de l’Europe et de la Méditerranée) in Marseille, south of France. ""


**Keywords:** French Presidency of the Council of the European Union, Global Approach to Research and Innovation, International Cooperation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'EERA Design Tools for Offshore Wind Farm Cluster' (EERA-DTOC).

assistant: **Concept**

The European Energy Research Alliance (EERA)  together with some high-impact industry partners addresses the call proposing an integrated and validated design tool combining the state-of-the-art wake, yield and electrical models available in the consortium, as a plug-in architecture with possibility for third party models. To decrease uncertainties around wind farm wake predictions, a small measurement campaign together with the new data available from the industry partners will enable better tuning, and eventually better modelling of the far-field of wind farm wakes.  With the large amount of offshore wind farms to be built in the next years, clusters of wind farms will appear at favourable locations, like in the German Bight and Dogger Bank. Large arrays of floating wind farms planned near long-distance grid cables independent of water depth will also start to appear in the next years. The planning and design of these clusters pose new challenges with regards to the siting of the connected wind farms, the design of the interconnecting grid structure and the integration of the large amount of power into the electricity supply systems. The concept of the EERA-DTOC project is to combine this expertise in a common integrated software tool for the optimised design of offshore wind farms and wind farm clusters acting as wind power plants. The only point less well known, due to the lack of good data so far, is the behaviour of the wind farm wake, in particular far-field wake. Therefore, a small measurement campaign is planned and collection of lidar data and high-resolution satellite images to get better data. Key industry actors working as end users of the software will help in the design of the tool, and will afterwards verify the performance of the tool using their own da
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Measuring and Modelling Tectonic CO2 Emissions Through Time' under Horizon Europe.

assistant: **Concept**

Geological processes governed paleo-atmospheric CO2 variations and exerted major control on past climate change beyond the million-year time scale. Vast deep carbon reservoirs are known to be activated at continental rifts, where the faulted lithosphere provides CO2 pathways and where recent surveys detected massive CO2 emissions. However, progress in quantifying natural CO2 degassing and its impact on past climate is impeded for 3 reasons: (1) current CO2 flux measurement techniques require labourintensive field surveys that can cover only small areas; (2) a consistent framework uniting geodynamic processes and CO2 transport to the surface is missing; (3) past CO2 flux from rifts is difficult to quantify because compilations do not account for geodynamic characteristics.EMERGE will enter uncharted territory by linking 3 innovative approaches. The project will: (1) advance airborne CO2 flux measurements via drones. Focusing on rifts in Kenya, Ethiopia, Czech Republic and Iceland, we will measure for the first time tectonic CO2 flux distributions of entire regions allowing unprecedented insight into subsurface CO2 pathways; (2) characterise geodynamic controls on lithospheric CO2 transport via novel numerical modelling techniques; and (3) integrate data of all known rifts since 540 million years ago to understand the role of tectonic degassing in shaping Earth’s climate through time.Zooming in on the geosphere-atmosphere interface, this project integrates interdisciplinary ideas and methods from geodynamics, micrometeorology, petrology, and paleoclimatology. EMERGE may generate broad impact on scientific and societal level: dronebased CO2 flux measurements will be a game changer in understanding tectonic CO2 release at rifts and other plate boundaries worldwide. The meth
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'The genetic basis of meningococcal and other life threatening bacterial infections of childhood'.

assistant: **Innovation**

Bacterial infection is the major cause of disability and death in children worldwide. We will use meningococcal disease (MD) as a model to understand genetic factors underlying susceptibility and severity of childhood bacterial infection which will then be applied to other childhood infections. We have established cohorts of patients with MD in Central and Southern Europe (CE,SE), UK and Africa as well as cohorts with other bacterial infections. We have established an inter-disciplinary team  with expertise in Infectious Diseases, Immunogenetics, Bio-informatics, Microbiology, Public Health and Vaccinology including SME and industrial partners. We have  already undertaken a genome wide study (GWAS) to identify genes causing susceptibility to meningococcal disease in a UK cohort. We identified complement factor H (fH) and fH-related (fHr) genes controlling MD susceptibility. This finding is fundamental to prevention as vaccines containing the MD fH receptor are undergoing trials. We will undertake GWAS on the CE, and SE MD cohorts, allowing meta analysis, and cross validation, and undertake GWAS on 2,500 Meningococcal Vaccine recipients. We will use next generation sequencing to identify the causal variants within the fH/fHr region and other regions implicated by pathway and severity analyses of the three MD GWAS and vaccine GWAS. We will match bacterial and host genetic variation and identify mechanisms of action of fH variants and other genes controlling susceptibility and severity using RNA expression, functional analyses and animal models. We will identify Mendelian defects and rare mutations as well as copy number variation and epi-genetic effects  using next generation sequencing and RNA sequencing in “extreme phenotype” cohorts with MD , pneumococcal ,staphylococc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Scaffolding Scalable Software Services' (S-CASE).

assistant: **Innovation**

The goal of S-CASE is to accelerate the software development lifecycle for cloud services by introducing a new agile prototyping paradigm that automates the process of mapping user requirements to concrete software specifications and generates operational code (RESTful services). S-CASE aspires to support software developers in identifying software requirements and business processes in various formats, including textual (requirements/use case documents), formal (UML diagrams), and visual (images of UML diagrams or storyboards) content. In order to realise this vision, S-CASE employs appropriate multimodal information processing techniques, such as natural language and image processing. S-CASE also aims to provide the appropriate mechanisms for synthesising composite executable workflows of resources (software solutions, services, and devices), both proprietary and open source. To this end, semantic matchmaking and service orchestration techniques will be applied for the dynamic discovery of resources and their composition into operational workflows that match the software developer envisaged requirements in the best possible way. All R&D outcomes will be integrated into the S-CASE realm, a cloud-based platform composed of tools for developers and service providers, open-source software repositories and a discoverable service ecosystem that provides the appropriate resources in the form of RESTful services. Three pilot applications will be developed and deployed in real operational environments by two industrial partners and one SME, in order to validate and evaluate the S-CASE paradigm. The aim of the pilots is to showcase how S-CASE can successfully meet different needs and technology requirements in the three domains of energy, social networks and cloud computing inf
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The Trouble with Gender' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Fifty years after the term ‘gender’ entered the vocabulary of social scientists, intense contestation about its meaning has broken out, spilling out of the academy into noisy, heated and wounding spats on social media. As the ‘gender wars’ rage, splintering the consensus that once held together feminist engagement in international policy arenas and international development on 'gender equality', TROUBGEN asks: what’s happened, why now and what can be done? TROUBGEN will draw on the PI’s extensive international networks formed over thirty years of scholarship and engagement and on an international team of advisors and collaborators to establish node points from which to begin a snowballing enquiry into the trouble with gender. It will explore the genealogies of different understandings, situating key thinkers, actors and networks of influence of the concept of 'gender' in international development - including Judith Butler, whose 1990 book Gender Trouble (from which this project takes its title) had such a catalytic effect. It will map the fault-lines of current disputes, examining their genesis, trajectories and encroachments in international development. It will analyse online/offline debates, untangling threads of meaning. It will create Dialogue on Gender spaces to convene and mediate deliberations that enquire into the differences that have now become so toxic and explosive, including devising a poly-vocal Verbatim theatre piece that uses the liminal space of the theatre to bring different perspectives into dialogue, and a Landscapes of Gender exhibition using the creative arts to visualise different strands, threads and meanings. It will evaluate the use of these dialogic and creative methodologies for bridge-work that might make visible and amplify common ground a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Molecular tattooing: azidated compounds pave the path towards light-activated covalent inhibitors for drug development' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Until now the greatest limitation in the application of bioactive compounds has been the inability of confining them specifically to single cells or subcellular components within the organism. Our recently synthesized photoactive forms of bioactive compounds solve this problem. We have developed effective chemical synthesis methods to attach an azide group to small drug-like molecules, which makes them photoactive. As a result, light irradiation can induce the covalent attachment of these molecules to their target enzymes. By controlling the timing and position of light irradiation it is possible to confine the effect of these molecules in time and space. It is important to emphasize that azidation is the smallest possible modification (adding 3 nitrogen atoms) that makes a compound photoactive and based on our experience it does not alter biological activities of most of the original compounds.Azidated inhibitors give unprecedented freedom to researchers because the covalent compound-target formations allow them to address questions which could not have been addressed before. Three major advantages are obtained by using azidated compounds 1: determination of small molecule interactome becomes highly effective, especially, the weak interactions can be determined, which was not possible before 2: it improves the pharmacodynamic and pharmacokinetic properties of biological compounds as the covalent attachment prolongs their effect. 3: Recently, we showed that photoactivation can be initiated by two-photon excitation, thereby confining the effect to femtoliter volumes and well-controlled spatial locations. This feature provides unprecedented spatial and temporal control in localizing the effect of biological compounds in cellular and subcelluler level in in vivo experiment
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Ampoules laser pre-breaking system', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

The object of this research consists of an innovative pre - breaking system of primary glass containers such as ampoules and cartridges that not only do they have direct contact with liquids for pharmaceutical use but also with cosmetic and foodstuffs. The main part of these glass containers (ampoules) are equipped with a pre breaking systems to help the end user open them. The current methods which are used (colour-break, scoring, one -point-cut) are quite difficult to handle due to the poor stability and consequent pollution of the internal liquid during the opening phase. The ceramical paints are not environmentally sound and therefore are bound to create pollution. Reduced machine up-time 85%. The aim of the project is to come up with and test a prototypal laser unit which can actually carry out a pre breaking etching without having to fall back on other polluting materials for external use, thus minimising the liquid contamination. The up-time will then be 92%.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Improving the processing of four fermented beverages from Eastern European countries', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

The project aims to improve three traditional fermented beverages as well as implementing the production of an innovative soy based fermented beverage. These products are Boza, a Turkish cereal based beverage, Ayran, a Turkish mildly fermented milk based slightly diluted yoghurt beverage drunk after water and salt addition and Matsony, a Georgian milk based beverage; these beverages usually contain a high number of viable micro-organisms when drunk. Additionally, a Fermented soy beverage developed in Po land will be the object of analyses, standardisation and implementation into production in a Polish SME. The project involves SME beverage manufacturers, technology and plant suppliers, RTD public bodies and Institutes who will study and characterize fermented beverages and from their natural micro-flora will select strains which play a role in the fermentation process in the production of both acids and flavours The ability of strains to prevent the growth of undesired foreign micro-organisms will be tested to see if they can play a role of natural protection on behalf of these beverages. These strains will be used as starters that will contribute to safeguarding the tastes of traditional products, the biodiversity of the micro-organisms of this ecosystem as well as ensuring the sensory and nutritional benefits in the case of the innovative product Fermented soy beverage. The project tasks will be carried out through trans-national cooperation actions between participants and using a multi stage research approach comprising analyses of drinks, chemical, nutritional, microbiological and sensory characteristics and, where applicable, their functional properties. In this way , the quality of fermented beverages will be improved in accordance with EU food hygiene standards
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Diagnosing Infections with Multi-Drug Resistant Microorganisms using AI-powered Genomic Antibiotic Susceptibility Prediction from Long-Read Sequencing Data'.

assistant: **Innovation**

The silent pandemic of antimicrobial resistance (AMR) is a growing global health crisis with a projected annual mortality rate of 10 million by 2050. Addressing this crisis critically depends on fast, accessible and precise diagnostics to improve detection and prevention of infection and guide antibiotic therapy. Current diagnostics often have insufficient turnaround time or data for timely detection and prevention of outbreaks or precision antibiotic therapy guidance, and accessibility is often limited due to the required infrastructure and expert personnel. To overcome these shortcomings, and address AMR, we are developing a diagnostic based on accelerated whole genome sequencing linked with AI-assisted data analysis. This project termed “DRAIGON” includes a consortium of internationally recognized experts in sequencing platform and assay development, bioinformatics and machine learning, clinical microbiology, infection prevention and control, antibiotic therapy and stewardship, and health economics to jointly develop our in vitro diagnostic solution to target virtually any pathogen-antibiotic combination. We propose to validate and demonstrate the clinical utility of DRAIGON focusing on bloodstream and prosthetic joint infections at five independent sites, including one located in a medium income country representative of areas with a high AMR burden and reduced access to laboratory infrastructure. The diagnostic will be easy to implement and functions as an early detection system to prevent the cross-border spread of pathogens. In rapidly and accurately providing pathogen ID and type, a comprehensive antibiogram, and outbreak cluster information directly from genome data and in a single assay, this innovative high-resolution diagnostic aims to reinforce the global f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Endophytic degrader bacteria for improving phytoremediation of organic xenobiotics' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

Phytoremediation is an experimental soil cleaning technology. One problem, presently limiting its applicability for certain organic pollutants, is insufficient degradation of the pollutants by the plants. As a result, the original compound or its metabolites build-up in the plants (poisoning the plants) or are volatilised through the leaves (causing a new environmental problem). This project aims to develop and test specific entophytic (-plant-internal) bacteria capable of degrading key pollutants. These new bacteria, when inoculated to the inside of plants, will degrade the pollutants as they are being transported from the roots to the leaves. This will reduce phytotoxicity and volatilisation of the pollutants. As a result, phytoremediation technology will be applicable to more toxic compounds or higher pollutant concentrations, and will maintain its social and regulatory appeal.