RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Clinically Oriented Translational Cancer Multilevel Modelling' (2007-2013).

assistant: **Concept**

The ContraCancrum i.e. the Clinically Oriented Translational Cancer Multilevel Modelling project aims at developing a composite multilevel platform for simulating malignant tumour development and tumour and normal tissue response to therapeutic modalities and treatment schedules. The project aims at having an impact primarily in (a) the better understanding of the natural phenomenon of cancer at different levels of biocomplexity and most importantly (b) the disease treatment optimization procedure in the patient's individualized context by simulating the response to various therapeutic regimens. The predictions of the simulators to be developed will rely on the imaging, histopathological, molecular and clinical data of the patient. Fundamental biological mechanisms involved in tumour development and tumour and normal tissue treatment response such as metabolism, cell cycle, tissue mechanics, cell survival following treatment etc. will be modelled. Stem cells will be addressed in the context of both tumour and normal tissue behaviour. From the mathematical point of view the simulators will exploit several discrete and continuous mathematics methods such as cellular automata, the generic Monte Carlo technique, finite elements, differential equations, novel dedicated algorithms etc. A study of the analogies of tumour growth with embryological development is expected to provide insights into both mechanisms. ContraCancrum will deploy two important clinical studies for validating the models, one on lung cancer and one on gliomas. The crucial validation work will be based on comparing the multi-level therapy simulation predictions with the actual medical data (including medical images), acquired before and after therapy. ContraCancrum aims to pave the way for translating clin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Event Prediction and Decision Support based on Huge Data from Physical-Social Systems' (EPPICS) under Seventh Framework.

assistant: **Objectives**

Miniaturisation, progress with energy issues and cost reductions have resulted in rapid growth in deployment of networked devices and sensors, very strongly connecting the internet with the physical world. With wide adoption of smartphones and social media, also people have become key sources of information about the physical world, corresponding events and the intents and plans of many individuals. With more than a billion of people organizing their lives electronically and sharing information via social platforms on the Internet and with the number of devices connected to the Internet already exceeding the number of people on earth and still growing to an estimated 50 billion devices by 2020, handling these massive amounts of data becomes a huge challenge. Surmounting this challenge, however, may give us previously unattainable understanding of events and changes in our surrounding environments. EPPICS will develop large scale adaptive methods to enable pervasive modelling, monitoring and predicting of events in the real world by extracting and combining data and information from physical and social sensors. Such methods will be integrated into a platform that will support citizens, authorities and organizations in taking informed and timely decisions when tackling real world events. Application domains will cover the intelligent management in urban settings with a particular focus on city-wide events management as well as water management, specifically monitoring and reacting to widespread floods. EPPICS will provide the technological and methodological framework for the capturing, integrating, modeling and forecasting of the large-scale hybrid information deriving from hundreds of sensors, thousands of cars and large-scale social media. The technology will enable th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Transmission of Classical Scientific and Philosophical Literature from Greek into Syriac and Arabic' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

It is often taken for granted that the Greek-Arabic translation movement (8th-10th c.) that made the whole bulk of Classical Greek scientific and philosophical literature available in Arabic (and that was later handed over to Europe in Latin translations) owes much to the preceding period in the history of transmission of this scientific and philosophical literature, namely translations into the Syriac language that were implemented by Aramaic-speaking Syriac Christians. The problem of continuity between the two periods however has not been tackled thoroughly in scholarship and thus the actual impact of the Syriac translations on later methods of translation has so far not been measured and assessed. One feasible solution to this problem in our understanding of the background to the Greek-Arabic translation movement is to implement a comprehensive comparison of Syriac and Arabic translations by means of lexicographical analysis. This project offers a research tool capable of allowing this comparison. It will combine methods of online lexicography and of corpus linguistics with the aim of presenting in a systematic and rationalized way the lexical data from the entire corpus of Syriac scientific and philosophical translations, comparing and analyzing its terminology and translation techniques, first, with the extant Greek originals and, secondly, with Arabic versions. The lexicographic database will be an effective instrument providing definite data for the study of Syriac and Arabic translations and their close connections. It will reveal how the Syriac translations along with underlying methods and tools that were put to use for the first time ever by Syriac Christians eventually determined the prosperity of the Islamic sciences. Fully endorsing a principle of open acc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Empowering consumers to PREVENT diet-related diseases through OMICS sciences' (PREVENTOMICS).

assistant: **Concept**

PREVENTOMICS builds a new paradigm in preventive personalised nutrition based on the potential of omics, especially metabolomics, accessible for everyone.The novelty relies on a new integration of genetic, nutritional and psychological factors and the application of state of the art metabolomics technologies and computational modelling of the metabolome, to assess the real incidence of disease-inducing factors on the organism, translating this information into personalized dietetic advice for the user, levering on ICT technologies. The main outcome from PREVENTOMICS is a novel mFood Platform, a unique-in-its-kind service, interoperable with current existing Apps for monitoring health status and with personalized nutrition software, thus opening the door to the personalization of any type of health treatment where combinations of genetic, biological, nutritional and psychological factors are important. PREVENTOMICS will be validated in 3 different case scenarios, performing relevant interventional studies with healthy and obese volunteers, to demonstrate its potential for personalization of nutrition at the 3 levels of the food value chain (processing and distribution, marketing and consuming), those closest to the end-users/consumers. Maximum impact will be ensured through well-balanced dissemination, standardarisation, communication and by the exploitation of the mFood platform, the menu recommendations, the personalised food elaboration and delivery, the food ingredients for personalised food and the personalised food shopping offer available for personal self-care and for professional services.


**Keywords:** Omics, Metabolomics, Metabolism Deregulation, Decision Support Systems, Biomarkers, Business Models, Consumer, behavioural change, food ingredients, personalis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Dynamic MOdelling of REsilience' (DynaMORE).

assistant: **Concept**

The project DynaMORE (Dynamic MOdelling of REsilience) exploits advanced mathematical modelling for the promotion of mental health and well-being. DynaMORE will generate the first personalised in-silico model of mental health in the face of adversity, that is, stress resilience. The model will be based on and validated against unique multi-scale longitudinal real-world empirical data sets. The development and testing of the model will substantially deepen our scientific understanding of the mechanisms of resilience. These insights will allow us to create mechanistically targeted interventions for the primary prevention of stress-related disorders. On this basis, DynaMORE will develop an entirely new mHealth product that will include model-based prognostic tools for monitoring of at-risk subjects and for automatised decision-making about timed, personalised interventions. The DynaMORE model will be openly available, whereas the interventions and surrounding application solutions (data analysis tools, information and communication technology (ICT)) will have a strong potential for commercial exploitation, which will be actively prepared within DynaMORE.These objectives will be achieved through the interdisciplinary collaboration of world-leading experts in the fields of (1) computer-modelling and simulation and multi-scale data integration (project area MODELLING), (2) bio-psycho-social research on mental health and resilience (area HUMAN LIVES), and (3) mHealth technology, including ambulatory monitoring and intervention, and ICT (area TECHNOLOGY). These will be supported, and results will be exploited, by an experienced management and impact maximisation team (area IMPACT).The overall aim of DynaMORE is to improve human lives by preventing stress-related mental health p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for '27th International Cosmic Ray Conference' under Fifth Framework.

assistant: **Concept**

The International Cosmic Ray Conference is held every two years under the auspices of the commission C4 on cosmic rays" of the International Union of Pure and Applied Physics (IUPAP). The last four conferences were held in Salt Lake City, USA (1999), Durban, South Africa (1997), Rome, Italy (1995) and Calgary, Canada (1993). The next 21th International Cosmic Ray Conference will take place in Hamburg, Germany, from August 7-15, 2001. The scope of the International Cosmic Ray Conference (ICRC) covers all aspects of cosmic ray research. Cosmic radiation has been defined as extraterrestrial charged particle radiation, i.e., it consists of a flux of electrons, positrons and nucleons with kinetic energies greater than 1000 eV that bombards the Earth from outside. With the technical capability of flying balloons high in the Earth atmosphere and launching satellites into extraterretrial space carrying lightweighted solid-state particle detectors, which was achieved after World War II, the original ground-based cosmic ray airshower experiments were supplemented by insitu measurements of the cosmic ray flux in interplanetary space. Today, detectors on board of spacecraft routinely provide spatia and temporal information on the particle energy spectra throughout the heliosphere.Besides the cosmic rays accelerated on our Sun and the planets, there is a strong component that originates in more distant astrophysical objects, located both in our own Galaxy and in extragalactic objects. The solar component has profound influence on the Earth atmosphere and magnetosphere ("space weather") with sometimes disturbing influences on the terrestrial communication technology. The origin of the galactic component has close connections to astronomy and astrophysics because it is responsible for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'VAScularised Tumour Organoids on a chip with human placenta vessels as a preclinical model for anticancer therapies.' (VASTO) under Horizon Europe.

assistant: **Objectives**

VASTO Proof of Concept aims to develop and test an innovative microfluidic-based platform, which allows to evaluate the efficacy of different cell immunotherapy strategies against solid tumours.  For this aim, we propose to microfabricate 3D solid tumour organoids with an aberrant microvascular network provided from the explant of human vessels. Although there are other different vessel-on-a-chip and/or microvascular network formation approaches that use in vitro cell monolayers, we are not aware of any solution covering human ex vivo blood vessel platform as it is proposed here. Therefore, we aim to recreate the existent mechano-chemical barriers characteristics of the tumour microenvironment in solid tumours with this novel ex vivo platform.With this technology, we can define a method to evaluate the efficacy of different immunotherapy-based strategies. Specifically, we focus on studying the effectivity of different Chimeric Antigen Receptor (CAR)-T cell therapies in solid tumours. Hence, the development of VASTO harbours the interest of CAR-T manufacturers to test these cell therapies against solid tumours. We will be able to asses CAR-T cell vascular extravasation, penetration into solid tumours and the CAR-T efficiency for tumour elimination. In addition to its applicability to liver cancer, the acquired knowledge in VASTO also could be extrapolated to any other kind tumours, but also in the development of an ex vivo platform for research in regenerative processes, by incorporating organoids from healthy donors, instead of malignant cells, and promoting functional vasculature, instead of aberrant one.Therefore, this human ex vivo platform will launch a new product to the market very attractive for clinical labs and companies, reducing animal experiments and providi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Content generation and delivery for 3D television' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The 3D4YOU project will develop the key elements of a practical 3D television system, particularly, the definition of a 3D delivery format and guidelines for a 3D content creation process. The project will develop 3D capture techniques, convert captured content for broadcasting and develop 3D coding for delivery via broadcast, i.e. suitable to transmit and make public.<br/>3D broadcasting is seen as the next major step in home entertainment. The cinema and computer games industries have already shown that there is considerable public demand for 3D content, but special glasses are needed which limits their appeal. 3D4YOU will address the consumer market which coexists with digital cinema and computer games. <br/>The 3D4YOU project aims to pave the way for the introduction a 3D TV system. The project will build on previous European research on 3D, such as the FP5 project ATTEST, which has enabled European organisations to become world leaders in this field. 3D4YOU will maintain the momentum built up and to capitalise on the wealth of experience of the participants in this project. <br/>Combining strenghts from different European countries, the 3D4YOU consortium covers all important aspects of the 3D broadcast chain. Bringing these expertises together, its objective is to deliver an end-to-end system for 3D high quality media. The generated knowledge will have sustainable effects on the European community. On one hand it will strengthen the existing expertise in programme making and will make sure that the media industry gains technical advances to compete with the world-wide competition. On the other hand it will give the European industry advanced knowledge to develop new products for the emerging market of 3D TV systems that will help to create and secure jobs.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Archaeology of Textile Production in the Kingdom of Meroe New approaches to cultural identity and economics in ancient Sudan and Nubia' (TexMeroe).

assistant: **Concept**

The TexMeroe project explores the textile industry of ancient Sudan and Nubia with the aim to improve our understanding of the little-known Meroitic kingdom (350BCE – 600CE). This study, the first of its kind, focusses on the exceptionally well-preserved archaeological textiles and tools to highlight the cultural attributes and economic bases of the Meroitic society. This objective will be achieved through the completion of two research-oriented Work Packages encompassing research stays, innovative training, and international collaborations with multidisciplinary experts. The data collected at archaeological sites and museums will not only provide a detailed analysis of manufacturing techniques but also assist in recognising textiles as a culturally significant medium. Textiles and textile implements will be used to study the economic immersion of raw materials, the organisation and outlay of craft production, and its trading mechanisms, thereby reconstructing important aspects of the Nile valley’s micro- and macro-economic environment. TexMeroe will provide a unique understanding of the textile craft development between the Pharaonic heritage, the Mediterranean influences, and the local sub-Saharan African traditions, helping to decipher and define the cultural identity and history of the Meroitic kingdom. TexMeroe is hosted by the University of Copenhagen’s Centre for Textile Research (CTR), a world-wide leader in the field of ancient textile studies. The project will benefit from CTR’s optimal research and training environment while contributing to the expansion of its global scientific network. The results will be communicated through a series of academic publications and conferences, as well as an Open Access online exhibition accessible to a broader audience. In S
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Multi-scale modelling of waves of porous media with applications to acoustic control and biomechanics'.

assistant: **Objectives**

Novel techniques will be developed to model the mechanics of porous media and elucidate wave propagation characteristics in these complex two-component heterogeneous materials. This will establish a more rigorous theoretical framework and provide deeper physical insight than currently possible. The applications and natural occurrence of such media are widespread, with important applications in acoustics, bio-mechanics, geophysics and engineering. Within this proposal, two areas of application will be explored in collaboration with non-academic partners. Firstly, results will underpin methods to better control environmental noise. As can be seen from the EU’s Policy on Environmental Noise this is an issue of significant concern, the policy stating that “The largest impact of environmental noise is on annoyance and sleep disturbance, health effects of noise to which more than 30% of EU population may be exposed. The external costs of noise in the EU amounts to at least 0.35% of its GDP, but much higher values may be found as new findings become available. In general, it is considered amongst the most relevant environment & health problems, just behind the impact of air quality.” The methods developed will have significant application to acoustic optimisation and control. Besides acoustic optimisation, determination of wave characteristics and better modelling of porous media have profound implications in modelling bone. Bone is a heterogeneous material with a complex hierarchical structure, occurring in two main forms, a dense solid and a porous medium filled by a viscous marrow. The EU’s Executive Agency for Health and Consumers estimates that 22% of the EU population experience long-term muscle, bone and joint problems, from which significant economic and social issues