RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Strengthening a comprehensive approach to preventing and counteracting radicalisation based on a universal  evIdeNce-based moDEl for Evaluation of raDicalisation prevention and mitigation' (INDEED).

assistant: **Concept**

INDEED aims to strengthen the knowledge, capabilities and skills of PVE/CVE and De-radicalisation first-line practitioners and policy makers in designing, planning, implementation and in evaluating initiatives in the field, based on evidence-based approach. INDEED builds from the state-of-the-art, utilising the scientific and practical strengths of recent activities - enhancing them with complementary features to drive advancements and curb a growing rise of radical views and violent behaviour threatening security. The INDEED methodological framework is based on the '5I' approach i.e 5 project phases: Identify; Involve; Innovate; Implement;  Impact. At the core of INDEED's work methodology is an interdisciplinary and participatory approach, which includes the co-creation of individual project phases and implementing them with the close engagement of multi-sectoral stakeholders. The creation of SMART Hubs (Stakeholder Multisectoral Anti-Radicalisation Teams) as part of INDEED is intended to facilitate this process.The selected results of the project are:1)The Universal Evidence-Based Model (EBEM) for evaluation of radicalisation prevention and mitigation; 2)A practical EBEM-based Evaluation Tool;3)A collection of user-friendly repositories (repositories of radicalisation factors and pathways into radicalisation; factors strengthening resilience to radicalisation; repositories of evidence-based practices) for practical use by practitioners and policy makers;4)Targeted curricula and trainings (offline/online);5)Lessons Learnt and Policy recommendations.All results will be integrated and openly accessible in the INDEED multilingual Toolkit for practitioners and policy makers in the field for the entire lifecycle of PVE/CVE and De-radicalisation initiatives, from design to e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'A Predictive Coding Perspective of Brain Dynamics: the case of Oscillatory Travelling Waves' (OSCI-PRED).

assistant: **Innovation**

One of the most exciting yet puzzling questions in Neuroscience is how the brain coordinates the activity between different areas, integrating distinct representations into conscious percepts and thoughts. For decades neuroscientists have investigated how the brain orchestrates diverse regions activity, pointing at oscillations as one of the key mechanisms involved in such a process. However, previous research has mainly focused on the temporal aspect of oscillatory dynamics, largely overlooking how oscillations propagate through the brain. Although rhythmic traveling waves have recently gained renewed interest, their functional role and relation to cognitive functions remain largely unknown. In this project, I will address this fundamental question: what is the role of oscillatory traveling waves in brain dynamics? I plan to take on this challenge using a multi-scale computational approach, modeling neural dynamics within and between cortical regions, as well as cortical-thalamic interactions. Importantly, the novelty of this approach consists in framing the model in the light of Predictive Coding principles, to test the compelling yet striking hypothesis that traveling waves encode Predictions and Prediction-Errors. The results of the simulations will be compared against experimental recordings in human participants to validate and assess the models predictions. Lastly, some implementations will turn into deep learning architectures, to test their dynamics in visual tasks while improving current models of artificial vision. All in all, this proposal can significantly advance our understanding of the neurophysiological mechanisms involved in sensory and cognitive functions, testing whether and how oscillatory traveling waves are a critical mechanism in neural dynamics,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Design driven development of touch sensitive luminous flexible plastics for applications in care & well-being' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

In Light.Touch.Matters, product designers and material researchers will collaborate to jointly develop a fully new generation of smart materials that combine touch sensitivity with luminosity, based on latest developments in polymeric piezo materials and flexible OLEDs. Manufactured on plastic substrates, these novel ‘light touch materials’ will be thin, flexible and formable, allowing seamless integration into products. They promise to greatly expand design freedom and unlock totally new modes of product-user interaction, enabling us to take the next step in product design: using touch sensitivity and luminosity to produce simple, affordable and intuitive user interfaces so that eventually ‘the product becomes the user interface’. Light.Touch.Matters focuses on products for care and well-being applications that can help consumers feel better, monitor or improve their health and increase comfort, such as rehabilitation aids, wearable alarms, and diet coaches, though we expect strong spin-off to other sectors. Light.Touch.Matters will use a proprietary design-driven research methodology based a comprehensive body of industrial product design knowledge that has been built up over the past decades. It consists of iterated cycles of materials-inspired and design-driven materials research with direct and prolonged design-researcher interaction, leading to a convergence of the conceptual designs and feasible materials in 4-6 interaction showcases. Analysis of results will include end user value, commercial value and environmental impact (LCA/critical materials). The design-driven research on integrated piezo plastics and OLEDs can directly contribute to innovation and competitiveness in a large number of related sectors, many of which are strategic to the EU: not only design,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Device oriented molecular spin filter based interfaces' (DELICE) targeting Horizon 2020.

assistant: **Abstract**

We live in a constantly changing society in which information and communication are at the basis of our economy. To keep progressing is essential to investigate new feasible ways to control and manipulate information in order to develop faster, smaller and less consuming devices. Organic Spintronics has emerged as a promising field to develop low-cost, mechanically-flexible and multi-functional devices in which information is carried not only by the charge but also by the spin of electrons. However, the injection and transport of the spin information through a device remains challenging, being organic/inorganic interfaces key to overcome this limitation. DELICE addresses the interface engineering in organic spintronics, aiming to profit from unique molecular capabilities for the development of highly performant chemically-tailored organic spintronic devices. In particular, DELICE focuses on exploiting the predicted spin filtering behavior of some organometallic molecules to obtain highly spin-polarized interfaces, enhancing the spin injection from ferromagnetic surface or even creating spin-polarization on non-magnetic metal surfaces. These so-called spinterfaces will be implemented in organic spintronic devices, spin valves, in order to determine the impact they have on the device performances. While organics have been mainly used as passive spacers in such devices, DELICE plans to go beyond the state of the art by actively exploiting the molecule’s spin filtering capability to improve device performances. A thorough characterization of the spinterfaces properties together with their implementation in real devices will provide us with valuable knowledge about the role of interfaces in devices. The technological potential of such a result represents a major step towards
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Extending information society networks to Western Balkan countries', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

IS2WeB is a Specific Support Action aiming to identify suitable research organisations in the Western Balkan countries and assist them to get informed about and actively participate in EU-funded research in the field of Information Society Technologies.The specific objectives of IS2WeB are to:- Identify promising research organisations in the Western Balkan Region suitable for participation in future IST research activities, defining criteria for their selection.- Provide mentoring / tutoring on IST programme opportunities and procedures to the identified research organisations as well as familiarize them with the European R&D culture.- Transfer EU research results and technologies related to selected strategic objectives of the IST programme in order to assist the identified research organisations elaborate ideas for future research proposals.- Facilitate the development of networks between research organisations in the Western Balkan region and the EU in order to exchange ideas and pursue joint research collaboration.IS2WeB will contribute to the Commission's priority to open up the European Research Area in the Western Balkan region and pave the way for future EU-Western Balkan scientific and technological co-operation. IS2WeB will support this co-operation by facilitating independent and self-sustaining IST research activities and promoting the European R&D culture in the region, with the ultimate goal of extending Information Society Networks to the Western Balkan countries. All countries in the Western Balkan region are represented in the project: Albania, FYR of Macedonia, Bosnia-Herzegovina, Serbia & Montenegro and Croatia. The project's duration is 30 months.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Harmonising and Unifying Blood Metabolomic Analysis Networks' (HUMAN).

assistant: **Innovation**

Metabolomics provides a real-time view of the metabolic state of the examined samples. The past decade the field showed strong growth, however limitations intrinsic to the field hinder further application in epidemiology level. Key obstacles include: variety of analyte molecular structures, slow marker identification, large differences in concentrations, poor validation, incomplete combination of data from different analyses and fragmentation of research. The consortium brings together scientists from different complementary disciplines and sectors to collaborate and set a research training network, combining infrastructure experience, knowledge and skills. The research scope is to identify the source of problems that hinder development, and recommend measures to overcome these. Training throughresearch will promote a new generation of omics researchers. Networking, joining forces via secondments will enhance research productivity transfer of knowledge. The project will train 10 ESRs in work-packages aiming toward improvement of design of experiment, harmonization of analytical methods, improved Data Mining and biochemical pathway analysis and translational research. Application will be in the study of blood metabolome of exhaustive physical exercise. We aim to study sample stability & preparation (including blood and alternative forms such as dried blood spots), biomarker identification, exploitation of multiple datasets, promote standard procedures, develop robust pipelines, develop and implement machine searchable notations of metadata, central database for data storage, compare datasets, automate cross-laboratory data combination, develop novel algorithms for multidimensional data mining and reconstruct biochemical pathways. The overall goal is to train the ESRs in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Unraveling the circuits of locomotion with opto-genetic manipulation of neuronal activity in awake behaving animals'.

assistant: **Innovation**

Locomotion relies on neural networks called central pattern generators (CPGs) that generate periodic motor commands for rhythmic movements. The manipulation of electrical activity and cell signaling in specific neuron type using light gated receptors enables us today to dissect the specific neuronal circuits forming the CPGs, and understand the dynamic role of sensory inputs in awake behaving animals.During my work in UC Berkeley, I developed the use of light gated receptors in vivo (Szobota 2007, Pautot 2008 and Wyart 2009). This novel approach enables us to test directly the role of specific pattern of activity in genetically identified neurons for shaping the complex locomotor behaviors.Using a combination of targeted gene expression and optical tools for monitoring and manipulating neuronal activity (“optogenetics”) in awake behaving animals, we have revealed the role of mysterious cells present at the interface between the spinal cord and the central canal: the cerebrospinal fluid (CSF) contacting neurons. I demonstrated that during early development in low vertebrates these cells provide the positive drive to the spinal central pattern generators for spontaneous locomotion (Wyart et al 2009).My future plan focuses on investigating further the circuits of locomotion in the healthy and severed spinal cord. My project consists in three distinct aims:Aim 1. To examine the chemo- and mechano-sensory functions of spinalCSF-contacting neuronsAim 2. To elucidate the role of dynamic sensory feedback for triggeringtransitions during locomotionAim 3. To improve recovery of function after spinal cord injury usingoptogenetics
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Atmospheric oxygen as a driver of plant evolution over the past 400 million years' (OXYEVOL) targeting Seventh Framework.

assistant: **Abstract**

The evolution of complex organisms over one billion years ago is intimately linked with a rise in atmospheric oxygen levels (O2) over a critical threshold that would support essential metabolic processes. Over the past 500 million years O2 has varied between lows of 10% to  highs of 35%, compared with current ambient levels of ~21%.Critical events in animal evolutionary history have been linked with shifts in atmospheric O2 such as the origination and radiation of mammals and selective extinction of many land vertebrate groups, at three of the five great mass extinction boundaries. The potential role of O2 as a driver of plant evolution has been almost completely overlooked, despite evidence from space science which shows that sub-ambient O2 can negatively impact all aspects of plant reproduction, phloem loading and photosynthesis. This proposal will address this severe gap in our knowledge of the importance of O2 in shaping patterns in plant evolution, by investigating the role of long-term trends in atmospheric O2 on the timing of major reproductive and vegetative innovations in the plant fossil record. This palaeobotanical approach utilizing the plant fossil record will be coupled with a series of highly novel ‘atmospheric miniworld’ experiments where representative plant taxa from all three major reproductive grades will be subjected to the atmospheric O2:CO2 conditions into which they likely originated and diversified. We will address whether tipping points in the ecological dominance of different evolutionary groups of land plants (angiosperms/ gymnosperms/ pteridophytes) were driven by shifts in prevailing atmospheric O2 content. We will achieve these objectives by conducting controlled competition experiments incorporating all three reproductive grades in miniwo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Bioresorbable Polymers for Medical Applications' to be submitted under Sixth Framework.

assistant: **Abstract**

The aim is to synthesise a series of novel biodegradable polymers consisting of polyoxonorbornene backbones with poly (hydroxyacid) side chains, and to study the variation in physical and mechanical properties of these polymers as a function of degradation under simulated biological conditions. A series of mono- and did-alcohol substituted oxonorbornenes will be synthesised and used as initiators for the ring opening polymerisation of lactate and glycoside to make oxonorbornenyl polyhydroxyacid macro monomers which will then be subjected to ring opening metathesis polymerisation (ROMP) to prepare the target biodegradable polymers. This synthetic approach will give complete control of the side chain and backbone chain lengths. This strategy will allow the study of variables such as the nature of the ROMP fragment, the length and composition of the degradable side chain, the size of the backbone, and the side chain density of the polymer prior to degradation. This project brings together a multi-disciplinary research team to develop bioresorbable polymers, which degrade in such a way that their mechanical properties change gradually from a rigid material to an increasingly flexible material before bioresorption is complete. In this way increasing load is introduced gradually onto the supported bone or tissue, which aids the healing process. This feature, combined with good mechanical properties on implantation would lead to the use of these materials in biomedical applications such as temporary hard and soft tissue fixation. Current implant polymers (polylactide, polyglycolide) do not provide this behaviour, with mass loss resulting in relatively sudden loss of mechanical properties on degradation, but no continuum of change from inelastic to elastic behaviour. The medica
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Functional genomics of non-coding mutations in regulatory regions of four metabolic tissues, and their involvement into type 2 diabetes through large-scale sequencing' (Reg-Seq).

assistant: **Innovation**

Type 2 diabetes (T2D) is a complex systemic metabolic disorder which has developed into a global major health problem responsible for early morbidities and mortality. T2D is a multifactorial disease, resulting from progressive alteration of insulin secretion from beta cells in pancreatic islets, on a background of resistance to insulin action in various organs and tissues, including liver, skeletal muscle and adipose tissue. T2D heritability is estimated around 40-70%. Genome-wide association studies identified more than 90 T2D-associated common variants, but altogether they explain less than 15% of T2D inheritance. Rare loss-of-function coding variants may contribute to T2D risk. Moreover, recent studies suggested the putative impact on T2D risk of functional non-coding variants within active enhancers of pancreatic islets; but tissue-specific regulatory regions have remained largely unexplored by genetic epidemiology studies. I intend to make progress in T2D genetic epidemiology and physiology by extending genetic investigation to frequent and rare mutations in non-coding regulatory regions on a whole-genome basis. In the Reg-Seq project, I propose the next-generation sequencing (NGS) of most relevant DNA regulatory sequences of four key metabolic tissues for T2D (pancreatic islets, liver, muscle and adipose tissue) in large well-phenotyped prospective populations (N=10,000 samples), followed by a replication in additional cohorts and by comprehensive functional experiments when genetic associations are identified. This project should lead to the identification of new functional genetic markers and pathways involved in T2D risk and development, and should help to stratify the T2D population for precision medicine, which is one of the major goals of the EU-Horizon 2020