RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'YOUCOUNT - EMPOWERING YOUTH AND COCREATING SOCIAL INNOVATIONS AND POLICYMAKING THROUGH YOUTH-FOCUSED CITIZEN SOCIAL SCIENCE' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

In Europe, and globally, substantial numbers of young people are at risk of social exclusion, and there is therefore a pressing need to develop more knowledge and innovation to create more inclusive and youth-friendly societies. Citizen social science might contribute to these needs, but the actual outcomes of citizen social science and its innovative potential is uncertain.  YOUCOUNT will therefore, through cocreative youth citizen social science (Y-CSS) including youths in the age of 15- 29 years as citizen scientists, produce new knowledge of positive drivers for social inclusion of youth at risk of exclusion, and cocreate innovations and policy-making. Moreover, to provide evidence of the actual outcomes of Y-CSS through hands on citizen science activities. The project includes four substudies: 1) Development of a framework for Y-CSS together with a transdisciplinary consortium and multilevel platform of key experts and stakeholders in a European and international setting. 2) Implementation of a multiple case study of Y-CSS projects in nine countries across Europe where over 900 young citizen scientists and nine local living labs will cocreate innovations together. 3) Mixed-methods evaluation of the outcomes and impact of the Y-CSS activities, and a multi-criteria assessment of the costs and benefits of Y-CSS, and 4) Creation of social and scientific impact through widespread scaling up and continuity. These activities will lead to robust knowledge and scientifically reasoned measures to promote Y-CSS and social change. The project will support dissemination and education in Y- CSS, and make synergies with other CS related projects and initiatives, in particularly with citizen social science.


**Keywords:** Citizen social science, science communication, youthfocuse
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Opening the black box: Imaging microbial behaviour inside rock' (MIRO).

assistant: **Concept**

The ubiquity and diversity of microbes make them natural, cost effective and sustainable agents for driving a wide range of subsurface engineering and remediation technologies, such as CO2 sequestration, oil recovery, sealing rock for CO2 and nuclear waste storage, and erosion control. Yet, their implementation is limited because we know too little about i) how to inject the microbes to the precise location where they are needed, and once there, ii) how they behave. The subsurface is a black box. MIRO will open this box, using X-ray and electron nanotomography, to provide 3D movies of microbe - rock – fluid interactions. Nanoscale understanding is needed for predicting how to inject microbes for decontaminating aquifers and for enhancing oil recovery from reservoirs nearing the end of their productive lifetime. Researchers have already used X-ray tomography to visualize internal structures in single cells and the nanostructure of rocks. During MIRO, I will transfer this approach to biogeochemistry and add new length and time scales to the study of microbial processes in situ, inside rock pores. Strong industry links, provided by my host, and collaboration with scientists and engineers, who will test my developments at field scale, will ensure implementation. MIRO is a multidisciplinary project that builds on my background in biogeochemistry and will diversify my competencies in tomography, computational methods and additional nanoscale techniques. Being able to pioneer a whole new approach, and contribute to advancing Europe’s technology assets for solving imminent environmental, energy and engineering challenges, will open new collaborations and projects with leading scientists in academia and industry. The training, mentoring and support offered by my host, Prof. Susa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Biodegradable Bio-based Bioactive Packaging Technology for Supporting Food Safety' to be submitted under Horizon Europe.

assistant: **Abstract**

This proposal tackles the urgent need to replace fossil-carbon-based plastics in food production systems by developing bio-based, biodegradable materials inspired by nature. Through interdisciplinary research and innovative design, we aim to create nature-inspired food packaging that not only minimizes environmental impact but also opens up a world of possibilities for sustainable food production. By maintaining the functional benefits of conventional plastics, ensuring biodegradability and sustainability throughout the product lifecycle, we are paving the way to replace fossil-carbon-based plastics. We aim to pioneer phages as antimicrobials in food packaging, sharing our PhagTec delivery system and Bio4Pack technology with other groups under this funding program. This will extend the application to agricultural, environmental, and medical sectors.Bacterial contamination, especially from Salmonella, Campylobacter, and Listeria, poses a significant challenge in poultry consumption. It reduces shelf-life and contributes to food waste and non-degradable packaging waste. Bio4Pack offers biodegradable, smart packaging solutions made from bio-based polymers to address this. The innovative PhagTec delivery system releases phages upon detecting the pathogen proteases (Salmonella-specific), providing antimicrobial properties that reduce the need for antibiotics. Nature-inspired phage coatings are consumer-safe and environmentally friendly and ensure long-term anti-pathogen effectiveness with full compostability.Our multifaceted approach involves an advisory board of experts in agriculture, industry, phage technology, LCA, regulatory guidance, and collaboration with other EU-funded projects. We propose an interdisciplinary strategy, including short scientific missions, events, a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Benchmarking the knowledge driven industrial organisation' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

Enterprise organisation has changed radically over the course of the last 10 years and rapid changes are certain to continue. The emergence of new manufacturing technologies, spurred by intense competition, will lead to dramatically new products and processes. New management and labour practices, organisational structures, and decision-making methods will also emerge as complements to new products and processes. The aim of the present accompanying measure BEINORG is to contribute to solving the present lack of empirical consolidation of the experience carried out in Europe on the emerging knowledge driven industrial organisation paradigms and to elaborate specific benchmarks for good practice, notably in the generation of new employment via start ups.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Improving the Continuity of patient care Through Identification and implementation of Novel patient handoff processes in Europe' (HANDOVER).

assistant: **Concept**

Research has shown that every year 30,000 European patients suffer preventable harm during treatment. It is estimated there were potentially 1,735 avoidable deaths in 2004. The financial cost of avoidable adverse events is reckoned at €167 million, 1% of hospitals’ total budget, due to longer hospital stays and additional treatment. Many of these adverse events relate to handoff in care. Poor continuity of clinical care (with multiple provider involvement), either at a patient’s referral to a hospital by a primary care specialist or at a patient’s discharge from the hospital, is a critical aspect of a patient’s care. Incomplete handoffs to a secondary/tertiary care unit or discharge from hospital can lead to adverse events for patients that may ultimately lead to either life threatening situations during treatment/surgery or avoidable treatment and / or re-hospitalizations after the patient’s discharge. Care transitions are especially important for vulnerable groups as the elder and the very young as for high-risk patients with multiple co-morbidities. The overall objective the HANDOVER project is optimize the continuum of clinical care at the primary care hospital interface by reducing unnecessary and avoidable treatment - medical errors and loss of life, by identifying and studying best practices and creating standardized approaches to handoff communication at the primary care hospital interface and measuring the effectiveness of these practices in terms of costs and impact. Handoffs take as many forms as there are handoff scenarios. The idea of developing a single approach for all handoffs is not likely to be possible due to the diversity and complexity of healthcare. HANDOVER will therefore aim at providing standardised basic elements in handoff processes, which can
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Rule-Based Modelling' (RULE) under Seventh Framework.

assistant: **Objectives**

The purpose of this research programme is to contribute to the solution of a major problem in today’s systems biology: namely, the difficulty to bring mechanistic modelling to bear on full scale systems. Statistical, and experimental techniques have scaled up considerably in the last two decades. Mechanistic modelling, on the other hand, is still confined in much smaller scales. Witness the painstakingly slow scaling up of cellular signalling models, despite their central role in cell response. To address the problem, we build on a new modelling methodology, called the rule-based approach (RB), pioneered by the PI of this proposal, and hailed (in a recent Nature Methods article) as the “harbinger of an entirely new way of representing and studying cellular networks”. By exploiting the modularity of biological agents, RB breaks through the combinatorial challenge of describing and simulating signalling systems. But with the possibility of writing and running larger models, new questions come to the fore. To bring mechanistic modelling to the next level requires: innovative knowledge representation techniques to anchor modelling in the data-side of systems bi- ology; new means to tame the complexity of, and reason about, the parameter space of models; new concepts to identify meaningful observables in the highly stochastic behaviour of large and combinatorial models; and clean and structured languages to comprehend spatial aspects of the biological phenomenology. The realism accrued by working at larger scales gets one closer to the bottom-up reconstruction of behaviours at the heart of systems biology, and to an understanding of the computational architecture of complex biological networks. This research programme, firmly grounded in the mathematics of programming langua
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Multi-compartmental Organ-on-a-Chip'.

assistant: **Concept**

Drug development is stuck in an innovation gap, in which it incurs staggering expenses and takes many, ten to fifteen, years to get a drug to market, furthermore, during the process many animals are sacrificed in preclinical work, and in the end many times the results from the animal studies does not accurately predict what will happen in humans, resulting in failures, delays, and recalled drugs. There is currently a gap in the preclinical testing platform for therapeutics. Organ-on-a-chip technologies of closing this gap, and have the potential of curtailing the high experimental costs and complexities associated with in vivo studies, and eventually evolving into next generation tools for therapeutic validation and development. We propose that by using a multi-compartment microfluidic platform, while integrating synthetic biointeractive hydrogels into and between the compartments, we will be able to produce a multi-organ-on-a-chip which recapitulates organ-like functions in each compartment and a vascular-similar conduit system between compartments to produce an early stage human on-a-chip for future therapeutic assessment and development applications. This project aims to develop a preliminary human-on-a-chip device, initially focusing on a heart-, and liver-on-a-chip and an endothelialized-conduit system between and through the two organ compartments. Successful production of this platform will improve the therapeutic and pharmaceutical development pipeline, while also minimizing our reliance on animal testing in accordance with the needs and guidelines within the EU.The long term implications of this work would result in increasing the throughput of therapeutics, directly minimizing the cost of drug development and increasing the efficiency. This would lead to lower
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Gasdermin D is a novel effector in the extrinsic apoptosis pathway'.

assistant: **Innovation**

Pyroptosis is a highly inflammatory form of cell death that drives host protection against intracellular pathogens. Pyroptosis is initiated by inflammasome-activated inflammatory caspases (e.g., caspase-1/4/5/11), which cleave gasdermin D to trigger plasma membrane pores. In contrast, apoptosis is driven by apoptotic caspases (e.g. caspase-3/7/8/9), and is traditionally classified as an immunologically silent form of cell death that is important for development and maintenance of homeostasis. However, emerging studies suggest that caspase-8 activation during extrinsic apoptosis promotes inflammation by triggering the assembly of a proinflammatory, multi-protein complex called the NLRP3 inflammasome, through an ill-defined mechanism. A recent study identified a caspase-3 cleavage site within gasdermin D; cleavage of gasdermin D by apoptotic caspase-3 suppresses the cytotoxic function of this protein. These suggest a complex crosstalk between the pyroptosis and apoptosis. Therefore, the aim of this project is to investigate 1) novel proinflammatory functions of gasdermin D during extrinsic apoptosis; 2) the role of gasdermin D in caspase-8-dependent NLRP3 activation; and 3) the importance of caspase-3-mediated gasdermin D inactivation at steady state in vivo and during chemotherapy. This project will greatly enhance the skills and competence of the experienced researcher through advanced training and international mobility, and is in line with Horizon 2020 Work Programme objective.


**Keywords:** Cell death,  inflammasome,  gasdermin D,  apoptosis,  caspase-8,  TNF,  SMAC mimetic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Advanced studies in autonomous robotic systems' (1998-2002) under Fifth Framework.

assistant: **Objectives**

Training site fellowships in Advanced Studies for Autonomous Robotic Systems Dept. of Technology , Oerebro UniversityDESCRIPTION OF THE RESEARCH TRAINING AREAThe PhD training is in core technologies for autonomous robotic systems: perception, action, and reasoning. Perception is done by sensor hardware, including biomorphic sensors, and perceptual routines able to identify objects, events, and processes. Action provides motion and manipulation via the integration between perception and control - it incorporates perceptual routines and adapts to variations in these. Reasoning provides the connection between perception and action - it interprets perceptual data and translates it into actions to achieve a goal. Advanced aspects include:1 ) integration of core technologies for acting in unstructured/uncertain environments; and2) technologies enabling learning and adaptation and co-operative behavior. We encourage applications from fellows specializing in computational perception (sensors/sensing, intelligent data analysis); AI for robotics (e.g., reasoning under uncertainty, planning, scheduling, machine learning); robot kinematics and dynamics, and perception-based control of motion and manipulation.EXPERIENCE REQUIREDCandidates should be enrolled in PhD studies in their home institutions in one of the following areas: AI, electrical and electronic engineering, robotics/automation, signal processing/estimation, computer science.RECRUITMENT PLANWe will receive 8 fellows over a 4 years period. Each fellowship is between 3 and 12 months. A total of 48 person/month will be awarded. Applicants should contact Prof. Dimiter Driankov, Dept. of Technology, Oerebro University, 70182 Oerebro, Sweden, Dimiter.Driankov@tech.oru.se, tel +46-19-303799. Oerebro University is an equal oppo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Intelligent Self-describing Technical and Environmental Networks' (S-TEN).

assistant: **Innovation**

W3C envisages the future of the Web to be a Semantic Web", which is an extended web of machine-understandable information and automated services that go far beyond current capabilities. The objective of this project is to tap these new possibilities for applications in the technical domain, especially to provide support for decision makers in a complex and continuously changing environment. This support is based on applying rules and process knowledge on available data published to the web. The data comprises measurements, human observations and design information. Data acquisition and process control is assisted by self-describing devices, e.g. measurement sensors or intelligent sub-systems, installed in the considered technical systems. The technology will be demonstrated by applications in the field of electro-technical systems, decentralised energy systems and environmental measurement systems. Dissemination will take place through the project website, presentation of papers and demonstrations given at conferences and workshops, provision of publicity material and a user group.The user group will be the starting point for exploitation by both the consortium members directly and by partnerships outside the consortium. The key standardisation task is to move the current generation of standards for design, engineering and process monitoring data to OWL ontologies, and thus make the appropriate data models available for semantic web technologies. Innovations provided by the project will comprise an ontology that enables a device to announce its existence, position in a network, and the services it provides. Also, the capturing of human qualitative observations and their publication on the web with respect to a formal ontology, as well as the development of rules that ca
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'IMPLEMENTATION MAINTENANCE AND PROMOTION OF THE EDILIBE/EDITEUR STANDARDS SETS' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

IMPRESS aims to support implementation of electronic data interchange (EDI) standards in the book sector by maintaining an already researched EU EDIFACT message set. The project will be run by a Pan-European book sector EDI group using experienced consultants to perform technical tasks with expert working party guidance. Maintenance and promotion of the message set will be supported by implementation group servicing, help desk, e-mail and Internet facilities, with revision as appropriate to meet changing user demands. IMPRESS is expected to promote the success of EDI in the pan-European library-bookseller cycle.