RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'European Union Contest for Young Scientists 2012'.

assistant: **Innovation**

The European Union Contest for Young Scientists, an initiative of the European Commission, was set up in 1989 to promote the ideals of cooperation and interchange between young scientists. The Contest is the annual showcase of the best of European student scientific achievement and as such attracts widespread media interest. The 24th EU Contest of Young Scientists will be organised from 21st to 26th September 2012, in Bratislava, Slovak Republic, at Incheba Expo Bratislava. The Host organizer is Young Scientist of Slovakia in close cooperation with the Ministry of Education, Science, Research and Sport of the Slovak Republic.The EU Contest gives students the opportunity to compete with the best of their contemporaries at European level. The young scientists also have the chance to meet others with similar abilities and interests and to be guided by some of the most prominent scientists in Europe. In this way, the Commission seeks to strengthen the efforts made in each participating country to attract young people for careers in science and technology. The EU Contest for Young Scientists is part of the Science in Society activities managed by the Directorate-General for Research and Innovation of the European Commission. Within the Framework Programmes for Research and Technological Development, and the European Research Area, Science in Society aims to build a more harmonious relationship between scientific endeavour and the European society at large.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Identification and characterization of bacterial effectors that interfere with Transcriptional Gene Silencing in Arabidopsis' (BASILA), addressing dissemination and exploitation.

assistant: **Impact**

Transcriptional gene silencing (TGS) is an ancestral gene regulatory mechanism that operates at the level of chromatin and that involves various histone modifications as well as cytosine DNA methylation. In both plants and animals, DNA methylation transcriptionally silences transposable elements (TEs), repeats, as well as some protein-coding genes that carry TEs/repeats in their vicinity. Whereas DNA methylation has been extensively studied at particular stages of plants and animals development, its dynamics and biological relevance in response to biotic stresses, and particularly during bacterial infections, has just started to be examined and reported. Previous work from the host laboratory has revealed that disease-related genes are negatively regulated by DNA methylation and that DNA demethylation is required to enable proper plant innate immune response. Together, these results suggest that some yet-unknown bacterial virulence factors must have evolved to interfere with TGS to enable disease. The proposed project aims at identifying and characterizing such bacterial effectors as well as their interactants, namely epigenetic factors. To address these questions, the bacterial pathogen Pseudomonas syringae and the plant Arabidopsis thaliana will be used as model systems and biochemical, genetic, epigenomic and cell biology approaches combined. The proposed project sets the grounds for further mechanistic analyses of the effector-target complexes that will shed light on the precise mode of action of these epigenetic effectors and their targets. This study will not only unveil novel mechanisms of bacterial pathogenicity but also allow the identification of novel silencing factors and therefore enhance our fundamental knowledge of TGS mechanisms in plants and possibly ot
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Identification of novel immunomodulators in the human poxvirus molluscum contagiosum virus' (2007-2013) under Seventh Framework.

assistant: **Objectives**

Infectious diseases kill 16 million people world-wide each year. Understanding how the immune system functions to sense and fight pathogens is essential for the development of novel therapeutics. Poxviruses have evolved a wide-spectrum of open-reading frames (ORFs) encoding immunoregulators which bind host proteins and disrupt the antiviral immune response. These ORFs are acquired from the host and are incorporated into the terminal regions of the viral genome. The acquisition of this extensive ‘toolbox’ of immunoregulatory sequences over long periods of host-virus co-evolution make them highly incisive tools for revealing novel facets of host immune system under the continual selective pressure of pathogens. Most research on poxviral immunoregulation has been conducted using the genome of Vaccinia virus (VV), a virus that is not adapted to human infection. Molluscum Contagiosum virus (MCV), is the only known human–adapted poxvirus and causes a long-term infection with a relatively weak immune response from the host. It has a highly diverse genome with largely unique terminal ORFs only 10% of which currently have a known function. In this proposal, the Fellow will adopt biochemical and cell biology approaches to analyse the unique ORFs of MCV and identify sequences that modulate human anti-viral immunity. These viral immunoregulators will be characterised and used as a basis for the development of immunotherapeutics. This proposal is designed to utilize the strengths of both the Fellow and the Host lab to facilitate mutual transfer of knowledge and expertise for both parties. The host lab has a strong interest in studying poxviral immunoregulation, and the Fellow will provide the expertise and tools to allow these studies to yield novel findings. In turn, the Fellow wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'EURopean wide Innovative Procurement of Health Innovation' (EURIPHI), addressing dissemination and exploitation.

assistant: **Impact**

Public Procurement Organizations (PPO) are rethinking existing practices as currently, quality of care is compromised and they do not lead to economic most advantageous purchasing.PPO involved in different PPI/PCP are teaming up around a novel approach of Value Based Procurement (VBP) joined by national/regional procurement organizations and service providers with a common vision, a value based procurement of innovative solutions to enable the needed transformation of health and social care delivery. The EURIPHI consortium involves 14 PPO, 10 with a regional or national remit and service providers from 6 countries who together, procure for more than 200 care service providers. The European Health Public Procurement Alliance members are also contributing to the project. This provides a strong basis to build out a Value Based PPI Community of Practice (CoP) to successfully achieve one of the key objectives of the CSA.The EURIPHI common vision is to build out around a MEAT VBP framework which will be made accessible with adaptions necessary to support the cross-border PPI leading to “MEAT Value Based PPI”. Cross-border PPI-Legal guidance will be developed by legal expert partners.Innovative solutions will be identified in the fields of rapid diagnostic (RD) tools in infectious disease and in the most promising integrated care services (IC). The identification of specific demands and prioritization will be done by expert partners and through the establishment of the Health Regional Network including stakeholders.Following an open market consultation, case testing will be performed for 1-2 RD and 3-4 IC innovative solutions and serve as an input for the PPI or PCP writing of SC1-BHC-20-2020.Dissemination and exploitation will be done by partners with a European or Internatio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'decentraLizEd Data Governance for nExt geneRation internet'.

assistant: **Objectives**

LEDGER ensures data sovereignty and eliminates concentration of data in a few proprietary platforms by accelerating 34 bottom-up experiments on human-centric values (privacy-by-design, reliability, trustworthiness and openness as core values) and 6 verticals (Health, Finance, Media, Public Services and Energy plus a generic one 'Open Disruptive Innovation).LEDGER will overcome Non-technological (Admin burden, Searching costs, bias in grant distribution, lack of use cases, User awareness, Access to Finance, Lock-in, Entrepreneurial Discovery and Regulation gap) and Technological barriers (Lack of Standards, lack of playground environments and Access to knowledge).LEDGER´s architecture relies in Mission-oriented, Market pull, Entrepreneurial discovery, Smart funding and Open-Technology. LEDGER will build on EC projects related to data governance: DECODE, D-CENT and PIE NEWS. 400 teams will be activated to develop the best applications that will run through a Minimum Viable Product Builder including mentoring and access to the Distributed Ledger Technology from DEVUAN.org.Up to 200k euros for the best teams will get startups ready for Venture Capital, pre-Initial Coin Offering and/or crowdfunding.LEDGER partners complete the community building, discovery, tech transfer and sustainability cycle. FundingBox - European leader in Financial Support to Third Parties will attract startups from its 15.000 members platform. DYNE will bring researchers and developers from its 10.000 members. Blumorpho will engage Researchers (7.200), Entrepreneurs (7.400) and investors (800) to guarantee sustainability. Linking with other ecosystem this ads to 110.000 people incl. 60% of potential Human Centric Innovators. 80 evaluators and 40 State-of-the-Art experts will develop alternative models
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Fibre Reinforced Composite Reflectors for Concentrated Solar Power Plants' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The principle of concentrated solar power (CSP) is to reflect and focus solar energy collected from a wide area on to one point, using the thermal energy to produce steam or a hot liquid in order to transfer or store the energy.For this proposal, the solar collector will be made of carbon fibre composite material. This can be designed to be stiff (maintaining its position) whilst being light weight. For a similar sized currently used heliostat CSP, the structure would be self supporting (Sandwich structure) the weight would be 627kg, giving a weight saving of 80% of the backed structure and 23% of the unreinforced glass collector.This weight saving has benefits in terms of installation and transportation, but the main advantage of the weight saving is, the energy required to adjust the collector would be greatly reduced thus a reduced energy control system could move the collectors during service. With the metal components removed, corrosion resistance is greatly reduced.An advantage of a carbon fibre structure is the low coefficient of thermal expansion. In the areas that will benefit most from a CSP, the arid conditions produce high temperature variations daily.The technical goal of this project is to produce lightweight yet robust components for CSPcollector components. Materials and processes will be identified and exploited to optimise the product and issues preventing optimisation will be investigated and solved. This proposal will have several aspects of work. Design and production of a novel composite collector, producing an adequate reflective surface on the composite, ensuring composite supports for the reflective surface, protecting that surface, and evaluating the effectiveness of the product. Physical Vapour Deposition (PVD) will be considered to deposit a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Reusing Effluents from Agriculture to unLock the potential of Microalgae' (REALM).

assistant: **Concept**

REALM will transform nutrient-rich drain waters from soilless farms into value, by producing microalgae at reduced costs while treating water and capturing CO2 from the air. This concept will increase the circularity and profitability of microalgal production and soilless farming. The NordAqua and ALGACYCLE projects (NordForsk and EEA, respectively) have shown the feasibility of this concept in Finland and Portugal, and now REALM aims to demonstrate it at an industrial scale. Accordingly, two validation facilities will be installed in the Netherlands and Finland, and two demonstration facilities will be deployed in Portugal and Spain near soilless greenhouses. With know-how from the SABANA project (H2020), these facilities will operate photobioreactors under a turbidostatic regime (continuous harvest) for maximum productivity, using nutrient-rich wastewaters from the greenhouses. Growth and harvesting units will be powered by photovoltaic energy and automatically managed by novel sensors, while A.I.-based predictive models and a cloud-based monitoring system will assist production. Microalgal biomass will be processed by local downstream processing units using dairy industry supply chain as a working model. This concept will offer sustainable wastewater treatment technology to farmers by closing the nutrient loop and is expected to reduce microalgae production costs by >50%, whose savings will be used to increase the competitiveness of the proposed microalgae-based products, namely agrochemicals and aquafeed. A business model will be developed to propose the installation of multiple microalgae production facilities, next to soilless greenhouses, and connected to a centralised processing facility. The results generated by REALM will be disseminated so the demonstrated co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Computer assisted optimisation of the forming process of MMC components' (COFCOM) under Fourth Framework.

assistant: **Objectives**

The search for weight, energy and cost savings and for components with improved performance are key issues for the European automotive and aerospace industries. In the last decade, these industries have shown the feasibility of using MMC structural components via the manufacture of prototype components using standard metallurgical forming processes and their characterisation. The final objective of the project is to develop a methodology, in order to optimise the forming process (forging and extrusion) of any particulate reinforced MMC component based on the combination of a micro-mechanical model to predict MMCs constitutive mechanical behaviour at high temperatures with a finite element simulation of the forming process.In the objective of MMC parts series production, this methodology will provide optimised forming parameters (die design, temperature and hot working rate) to produce a MMC component:- Free of defects such as porosity, microstructural heterogeneity;- With minimised internal residual stresses;- With mechanical properties tailored to the in-service loading conditions. Moreover, this methodology will be a key tool for the prediction of the influence of the MMC composition: nature of the matrix, type and volume fraction of particles on the mechanical properties and microstructural quality of a forged or extruded component. It will thus result in a quick and low cost development of new MMC parts.In order to achieve the objective of the project, the technical programme is divided into two complementary stages including both theoreticaland experimental approaches:Stage 1: Development of the methodology and validation in the case of simple shape demonstrator parts;Stage 2: Validation of the methodology in the case of complex automotive and aeronautical componen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Statistical mechanics of granular materials: how can sand fill voids like a gas, flow like a liquid and sustain stresses like a solid?' under Sixth Framework.

assistant: **Concept**

Granular materials (e.g. sand, powders, concrete, seeds, pills and so on) are subject to a recent strong scientific interest: they are materials of fundamental importance for industry and agriculture. The economic impact of a better comprehension of their collective properties has been estimated to be of the order of the billions of dollars per year.The physics of granular materials has unveiled a large number of intriguing phenomena: granular systems can behave like gases, liquids or solids, depending on boundary conditions and intensity of the external driving. However, in all these three states", a granular system displays always specific and anomalous properties. In particular, dilute granular systems, fluidized by means of an external energy input, due to the non-conservative characters of their interaction, "violate" several fundamental principles of statistical physics, such as the second principle of thermodynamics, the equipartition of energy or the Maxwell-Boltzmann statistics.Packed granular systems (for example a buckle full of sand, tapped from the bottom) surprisingly reveal strong analogies with glassy systems (spin glass or structural glasses), showing disorder, frustration and very slow relaxation processes. In a word, a granular system, from the point of view of physics, is the perfect case study for modern non-equilibrium statistical mechanics. At the same time, a full understanding of granular systems can have real consequences in industrial and technological applications.The specific objective of this project is to join the two mainstreams of granular physics, that is, dense solid-like and dilute fluid-like granulars, investigating the transition between those two phases when external parameters (such as the intensity of the shaking or the global pa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Right-time Adaptive Particle Therapy Of canceR - Personalisation through anatomical plus biological adaptation'.

assistant: **Objectives**

The RAPTORplus consortium gathers excellent research institutions, academic hospitals and non-academic particle therapy (PT) centres, industrial corporations and public organisations. It offers a platform for intercultural, interdisciplinary and inter-sectoral training and education of doctoral candidates (DCs) in the field of medical physics focussing on right-time adaptive PT. The assembled infrastructure and expertise from academia, clinic and industry is needed to address the challenges of personalised adaptive PT.PT is a precise form of radiotherapy with a growing number of centres treating patients. It targets localised cancers while sparing healthy tissue, but might deliver suboptimal doses in case of anatomical changes. To exploit the full potential of PT, fast and safe online treatment adaptations must be enabled and performed if beneficial, e.g. indicated by image-based biomarkers, biological models or other response data. The research projects conducted at academic and non-academic facilities will tackle (1) the efficient realisation of online-adaptive PT (OAPT), (2) the technological completion for broad and safe use of OAPT, and (3) a further treatment personalisation by biomarker-based adaptation. The network uses a multi-sectoral approach to ensure that the DCs develop scientific, clinical and practical industry-relevant skills. The holistic training programme includes in-person training camps, online trainings, project-specific secondments, training in tutoring, research communication, entrepreneurship and science policy, and opportunities to participate in international conferences and professional networks. RAPTORplus will train the next generation of research leaders, medical physicists and entrepreneurs to be aware of the necessity of right-time adap