RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Development of full-range energy band matching photo-recharged Zn metal batteries' under Horizon Europe.

assistant: **Concept**

The full-range energy band matching (FEBM) photo-recharged Zn metal batteries (PRZMBs) that can convert solar energy into  electrochemical energy in one step are considered a totally clean energy system, which can not only avoid the usage of harmful  substances (Cr, Pb, etc.) in solar cells and reduce the usage of fossil fuels but also reduce the cost of large-scale power grids. In this  proposal, based on low-cost, environmentally friendly aqueous zinc metal batteries, a modified MoS2 material (m-MoS2) will be  employed as a photocathode by O substitution for partial S to increase the layer spacing and improve the electrochemical activity of  m-MoS2 (WP1). The electrochemical reaction process and kinetics will be studied by the precise control of the structure,  morphologies, and O contents in m-MoS2 to realize the aim of a capacity improvement of 100 mAh g-1 at 100 mA g-1 compared with  original MoS2. Subsequently, a precursor solid method will be employed to synthesize the m-MoS2/fCNTs composites with a covalent  bonding interface, which can avoid structural collapse during the cycling process and effectively improve the reversibility, and finally  to realize the goal of operation time over 1000 hours (WP1). Based on the tunability of layered MoS2, the relations between layers, O  contents of m-MoS2, and energy band structure will be studied to provide the foundation for the FEBM process. Finally, based on the  results from WP1-2, the energy band changes of m-MoS2 during cycling will be studied to screen out the proper energy band range  of m-MoS2 to construct a FEBM photoelectrode. In addition, the relationship between the photogenerated charge and the  electrochemical reaction mechanism (reaction kinetics, intercalation/phase conversion, and capacitive behavior) wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Inhibitor-Mediated Programming of Glycoforms' to be submitted under Horizon Europe.

assistant: **Abstract**

Site-directed mutagenesis revolutionised the study of proteins and enabled the development of protein-based therapeutics. Our long-term vision is to have equivalent impact through the precise manipulation of the glycans (carbohydrates) on cells and recombinant proteins that will enable the discovery and production of the next generation of therapies for cancer, neurodegeneration and other disease families. The glycans that are present on most proteins and cells have a substantial impact on their biological functions, yet the untemplated nature of their synthesis leads to inherent heterogeneity in both their structure and activity. This heterogeneity is very difficult to control, making it impossible to generate defined glycan ensembles with optimal activity using current technology. Here we present a radically new approach to the controlled manipulation of glycans that will be the functional equivalent of site-directed mutagenesis for manipulating proteins. We will use the delivery of computationally defined mixtures of enzyme-specific inhibitors to the site of glycan biosynthesis in the cell to tune the activity of glycosyltransferases. Our approach, termed Inhibitor-Mediated Programming of Glycoforms (IMProGlyco) will provide an effective strategy to manipulate the glycosylation machinery and thereby generate proteins with defined ensembles of glycans. It will enable the production of precision glycan engineered therapeutic proteins and vaccines. Moreover, shaping cellular glycan profiles will aid discovery science to uncover glycan functions and improve therapeutic cells, such as those used in Chimeric Antigen Receptors cell Therapy (CAR-T). Our technology will be adaptable and expandable into other cell types and organisms allowing glycan shaping in all areas of euk
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Kinesthetic Displays: Creating Embodied Experiences of Movement Using Vibrotactile Feedback' to be submitted under Horizon Europe.

assistant: **Abstract**

Kinesthesia – awareness of position and movement of body parts – is essential in all aspectsof life. Kinesthesia enables mundane activities such as typing or lifting a glass to our lips, aswell as feats like playing a piano concert or competing in an elite sport. It not only providesinformation about our body, but also helps form an embodied understanding of the world aroundus. Although kinesthesia is central to human experience, it is barely used in human-computerinteraction (HCI). However, existing methods like visual retargeting or auditory body illusionssuggest that such displays are possible. Vibration, exemplified by the Pinocchio Illusion, mightbe an ideal actuation method to convey kinesthetic information; however, the literature showsno systematic way to achieve this.I aim to design kinesthetic displays (KDs), general purpose devices that provide an embodiedexperience of movement. I will apply a sensorimotor perspective to the design of vibrotactilefeedback, building on my know-how of using sensorimotor contingencies for designing vibrotactilematerial experiences. In this project my team and I will design a series of prototype KDs whichwill be used to study how design decisions, stimulation parameters, and algorithms influencethe introspective experience of movement. The resulting data will be used to formulate designguidelines for KDs and to establish an empirical theory of sensorimotor interaction.KDs will transform remote and co-located training and skill sharing. KDs will help us betterunderstand our own bodies and provide amputees with sensory access to prosthetic limbs orother body augmentations. Finally, KDs will provide digital systems with an embodied channelof communication, revolutionizing how we interact with computers.


**Keywords:** Haptics, Embo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Usability Support Network'.

assistant: **Innovation**

Despite compelling evidence of the benefits of employing user centered design methods to produce more usable products, most development activity in Europe does not use these methods, with the result that most computer systems are unnecessarily difficult to use. UsabilityNet will provide a web site and support network to assist organisations with usability, user centered design and process improvement.The project is composed of partners that are world-leaders in usability, supported by sub-contractors in 11 other countries. It will identify the requirements of European industry and organise a workshop to obtain broad consensus on good practice. This will form the basis for a web site of global and local resources derived from previous projects including MUSiC, INUSE, RESPECT, Baseline, TRUMP, EMMUS and other sources.Topics covered will include how to: identify user needs and specify usability requirements; incorporate user centered design methods in the development process, make use of international standards, test whether a product meets usability requirements; assess usability maturity; and produce a business case for usability and calculate the cost-benefits.The web site will be supported by one or two day tutorials on usability and user centered design: four open tutorials and tutorials held at IST and other conferences. An email discussion group and help service will be established. UsabilityNet will set up local groups to organise meetings in at least 12 countries, to enable people working in usability or interested in usability to share experience and expertise. A European organisation will be set up to support the groups and maintain the web site after the end of UsabilityNet.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'European Union Action to Fight Environmental Crime' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Environmental crime is a threat to environmental, social and economic sustainability and is in conflict with key commitments and strategies of the European Union, including the Europe 2020 Strategy. EFFACE will propose effective and feasible policy options for the EU to combat environmental crime. The recently adopted Environmental Crime Directive, the Ship-Source Pollution Directive, and the new provisions of the Lisbon Treaty have created new instruments and opportunities for increasing the effectiveness of EU measures against environmental crime through harmonisation and co-ordination. However, utilisation of these opportunities suffers from a serious lack of information on environmental crime: e.g. harmonisation measures based on the new Article 83(2) TFEU depend on the availability of reliable information on the impacts of environmental crime. EFFACE will help to address this gap by generating relevant information. Drawing on a combination of quantitative and qualitative approaches and data and an in-depth investigation of different types of environmental crime, EFFACE will provide an assessment of the main costs, impacts and causes of environmental crime in the EU, including those linked to the EU, but occurring outside its territory, complemented by a comprehensive analysis of the status quo in terms of existing instruments, actors and institutions. A SWOT analysis will identify strengths, weaknesses, threats and opportunities associated with the EU’s current efforts to combat environmental crime. Feasible policy options for harmonisation and better co-ordination of actors will then be developed with the help of, i.a., typologies of different approaches to harmonisation, sanctioning and strategic enforcement. These policy options will consider the use of policy m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Harnessing the power of high altitude winds - the biggest energy resource yet unexploited by humankind'.

assistant: **Objectives**

Wind is our second largest energy source after solar. The conservative estimates state that wind could provide us with 1,800 TW of energy—100X more than the current global demand for power. But most of this wind is at high altitudes, and is available almost anywhere on the planet 24 hours per day, 7 days per week. The conventional wind turbines, although having improved immensely over the past decade, have hit a technological plateau: they cannot be made much taller to reach the strong, fast winds that blow at altitudes of 400+ meters.To address this challenge, we developed Skypull—a system made of an autonomous flying device (drone) connected by a tether to a ground power generator—which generates low cost electricity from abundant high altitude winds. Uniquely among the competition, we created and patented the highly efficient design of the flying device. We foresee incremental development over several variants to reach a 1 MW Skypull SP3 system by 2021, capable of generating electricity at €40-50/MWh. With that device in place we will grow the revenues from €2m in 2020 (3 units sold in Switzerland) to €140.3m in 2030 (200 units sold globally), with an IRR of 24%+.We will work closely with the Swiss energy utility AEM SA, that abandoned its plans on implementation of wind turbines and decided to explore the potential of Skypull. We have also built a broad partner network to build Skypull.The purpose of this Phase 1 project is to carry out the market and commercial feasibility for a reduced Skypull SP2 10-100 KW demonstrator, so that it could be sold in the off-grid contexts, generating first cash flows for the company to co-finance further development of a 1 MW variant.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Regulation of stem cell proliferation and differentiation by endothelial cells' to be submitted under Sixth Framework.

assistant: **Abstract**

Stem cells have the ability to both, self renew and differentiate into different cell types, what enables them to regenerate and repair tissues and organs. There are specialized niches of stem cells in the adult mammalian brain. Neural stem cells (NSC) are around blood vessels and it has been recently described that endothelial cells are able to regulate the proliferation, self-renewal and the induction of these NSC to neurons in vitro. This interplay could also result in increased angiogenesis because it h as recently been reported that NSCs are able to differenciate into endothelial cells. Moreover, the replenishment of the NSC niche with stem cells from the bone marrow can be regulated by endothelial cells. VEGF is a chemotatic cue for the migration of und ifferentiated neural progenitors, offering a mechanistic link between neurogenesis and angiogenesis in the nervous system. In the present work we will define the nature of the interactions between NSC and endothelial cells in the NSC niche, evaluating the role of the endothelium in the regulation of the NSC niche in vivo and identifying molecules involved. In order to determine whether blood vessels within the NSC niche serve as conduits for the circulating cells that replenish the niche we will determinate the fate, the origin and the mechanism of engrafted cells. Understanding the stem cell niche will provide a framework for the elucidation of stem cell function and regulation. In addition, it will provide us with valuable tools for adult stem cell therapy . The present project focuses on the role of vasculature as regulator of stem cell homeostasis and function.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Quantum mechanics and quantum field theory with quantum group symmetries' to be submitted under Fourth Framework.

assistant: **Abstract**

The general issue underlying my research project is whether quantum groups can be used to generalize the notion of symmetry transformations (either of spacetime or of internal degrees of freedom) in quantum field theory. Quantum group transfor- mations have already been implemented on some examples of quantum mechanical systems having a fixed number n > 1 of distinct particles. The main objective of my research project and collaboration is to find the general prescription to imple- ment quantum group transformations: I) on systems of identical particles; 2) on field operators to be introduced in second quantization. We would develop some breakthrough ideas (obtained in a very recent work of mine with Dr. P. Schupp), which allow to solve the apparent incompatibility of quantum group coproduct with Bose/Fermi statistics. Applications to physically relevant quantum group trans- formations such as deformed Poincari. Euclidean or internal (flavour) su(n) could follow.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'European structured research area for CAtalytic and Magnetic nanoMaterials', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The objective of the proposal is to support the creation of a European structured research area for catalytic and magnetic nanomaterials by integrating two DISs (ERIC and EIMM) operating in the fields of catalysts and nanomagnetism, and their plan to expand current activities in order to (1) obtain a larger coverage of industrial technologies/sectors and (2) extend the involvement to the activities of the relevant industrial partners. The aim is to create a realistic basis to achieve financial sustainability of the two DISs which will keep their own individual personality, but share knowledge and expertise, structure, equipment and other resources, to offer a broader and cost-effective range of services to companies, and in the long-term the vision is to provide new competences (deriving from the integrated collaboration) to new industrial sectors such as materials for nanomedicine, health care and diagnostics, to ICT, environment protection, and nanomaterials’ risk.Functional to this objective are also the possibilities a) to realize efficient synergies to reduce the management costs of the DISs, and to be more cost-effective for a structuring effect inside ERA, b) create a larger critical mass, and a broader spectrum of expertise and equipment, c) improve the attractiveness towards young researchers through a combination of high-profile science and educational activities in their favor, and d) enhance the visibility and develop more efficient politics for incorporating new partners in order to progressively expand the actual core partners.Reaching the objectives, implementing these activities will thus result in 1) an improved coordination in both research and innovation, through the management and cultural synergies between the two DISs (ERIC and EIMM); 2) a more rob
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Disease and vaccine monitoring based on non-invasive genital tract liquid biopsy sampling.' (URISAMP).

assistant: **Concept**

The ability to easily obtain appropriate and reliable biological samples is critical to advance life sciences  and public/personal health. Having a sample that is non-invasive and can be self-collected at home has major acceptance and feasibility advantages. Our team demonstrated that first-void urine (FVU) samples can replace clinician collected cervical samples to prevent cervical cancer caused by the Human Papilloma virus (HPV). Using the initial or first void urine stream is crucial here. Indeed, the outer layers of the epithelium of the genital tract exfoliate and together with the genital mucus form the utero-cervico-vaginal-smear, it accumulates between the labia minora, around the urethral opening and upon initiation of urination this discharge is washed away with the FVU. URISAMP uses HPV infection and vaccination models to prove the hypothesis that FVU is the ideal liquid genital tract biopsy to monitor immune response for women. URISAMP will 1) identify and validate analytical methods to detect the relatively low and fluctuating concentration of potential biomarkers in FVU; 2) provide protocols to study neutralizing antibodies  and look at antigen-antibody interaction; 3) demonstrate how FVU sampling can enhance our knowledge regarding the biology of HPV, genital tract immunology, mechanisms of infection and transmission, the biological basis of prevention and potential correlates of protection. URISAMP will contribute to simplify and facilitate sexually transmitted infection (STI) vaccine research and provide valuable data for disease modelling. Moreover, if URISAMP proves successful, and FVU can also replace other samples types (e.g.blood), applications will largely extend the STI field, and its impact as a novel diagnostic and prognostic tool for health as