RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Printing of Ultra-Thin, Flexible Perovskite Solar Cells and its Commercial Application' (PIPER).

assistant: **Innovation**

The impact of buildings to European final energy consumption has been assessed at 40%, making the building stock responsible for 36% of CO2 emissions. The reduction of energy consumption in buildings is the focus of the European 2020 strategy. EU’s essential policy instruments that encourage energy efficiency, retrofit measures and renewable production are: the Energy Efficiency Directive (EED), the Energy Performance of Building Directive (EPBD and EPBD recast) and the Renewable Energy Directive (RED). One of the major initiatives promoted by the EPBD recast is the implementation of nearly zero energy buildings (NZEBs) as the building objective from 2018 onwards. In the US, as well, several states’ strategic plans stipulate that all new residential buildings must be zero-net-energy (ZNE) by 2020, all new commercial buildings - by 2030, and 50% of existing commercial buildings must be retrofitted to ZNE by 2030. However currently available technologies pose challenges to reaching these objectives in cost-effective way. As an example, photovoltaic devices which bring high hopes and expectations to NZEBs, can currently only cover roofs, not allowing to optimally use the majority of building surface. They only generate energy from direct natural light and cannot be used on existing buildings without the need of severe structure modifications. Similar challenges (compliance with regulations, search for optimal efficiency-cost ratio, need for constant performance improvement while maintaining aesthetic features) are also faced by many other industries (automobile, aeronautics, consumer goods – electronics, clothing, etc.)Saule Sp. z o. o. (Saule Technologies) aims to address these challenges by introducing the first-on-the-market perovskite solar cells (PSC) which are effici
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Adaptation solutions to reduce climate change impact on health in the Mountain area' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

In the face of climate change, events like COVID-19 crisis with high impact in specific sectors demonstrated the importance of resilient societies. As such, it is vital to act with a level of urgency for climate change related impacts to health sector that are proportionate to the scale of the threat, be prepared and informed on the basis of the best-available science, and practise clear and consistent communications to all those involved. Therefore, in MOUNTADAPT, various regional and local authorities and community members will take the leadership to co-design, co-develop and test eleven state of the art climate adaptation solutions across the mountains biogeographical region, in Austria, Slovenia, France and Romania. A diversity of actors of the health system will also collaborate throughout the project to demonstrate the replicability of the solutions in a diversity of settings: within the Alpine mountains in Romania, outside Europe in the Pyrenees in Andora and beyond, in the continental area in Germany. MOUNTADAPT will develop robust models to better understand the impact of climate change on health (PR1). The project will cover the whole chain of response to a climate induced health emergency with monitoring tools (PR2) that will be directly linked to short term forecasts to communicate warnings (PR3) to the relevant stakeholders. An emergency management tool (PR4) will finally support health systems to optimally organise staff in crisis time. This will be supported by guidance for transforming the health system (PR5) and empowered actors with the training courses for healthcare professionals and awareness raising campaigns for citizens (PR6). Detailed monitoring protocols and impact assessment frameworks (PR7) will allow for a continuous evaluation of a range of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Biological Understanding of the CO2 and O2 LeveL in the ocEan', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

About 98% of the ocean’s biomass is composed of microorganisms like the tiny algae, phytoplankton. Tiny but mighty when it comes at capturing carbon dioxide (CO2). Phytoplankton acts for half of the Earth’s photosynthesis, allowing ocean’s to supply major living resources and dioxygen (O2). Microbial respiration is the other fundamental biological process that counterbalances photosynthesis and returns organic carbon back as CO2. Yet, despite ocean’s pivotal role in global climate, microbial respiration remains one of the least explored metabolic processes; so that, whether oligotrophic ocean is a net sink or source of CO2, is highly debated for the last 20 years. The BULLE project aims to evaluate the ocean’s metabolic balance between photosynthesis and respiration by looking at the production of CO2 evolved to that O2 consumed by marine bacteria, the so-called “respiratory quotient” (RQ). Limits of detection of biological CO2 production have left RQ measurements far behind the multitude of investigations of photosynthesis. BULLE will face these challenges using the most recent technologies. The project strongly relies on the multidisciplinary expertise I will share with my host lab to tackle this issue at both cellular and community level. Specifically, BULLE aims to (1) investigate how the chemical characteristics of nutrients (Fe and C) regulate the RQ in bacterial cells and (2) study the links between the RQ, net primary production and bacterial activities. An innovative aspect of BULLE is the implementation of continuous measurements of O2/N2 and pCO2 concentrations respiration, and the deployment of In Situ Oxygen Dynamic Autosampler (IODA) instrumentation in the coastal NW Mediterranean Sea. The training I will receive with BULLE will help me give my career a ne
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Design, synthesis and evaluation of potential group-1 and group-2 neuraminidase inhibitors' to be submitted under Seventh Framework.

assistant: **Abstract**

Influenza neuraminidase (NA) is the enzyme that releases influenza virions from the infected cells, cleaving the sialic acid receptor on host cells. It has been recently demonstrated that influenza A has neuraminidase subtypes that belong to two distinct subgroups. The crystal structures of the three subtypes N1, N4 and N8 (group-1 enzymes) were found to be virtually identical in the shapes of their active sites. However they were found to be different when compared to N2 and N9 subtypes (group-2 enzymes). In the case of N1, N4 and N8 subtypes, a loop of amino acids which includes the active site catalytic residue Asp 151, was found to adopt an unusual open conformation compared to the N2 and N9 subtypes in which loop-150 was of a closed conformation. The observation of different active site conformations between certain subtypes of group-1 and group-2 enzymes suggests that these two groups are not only genetically distinct but are also structurally distinct. The main objective of our project is to develop new specific neuraminidase inhibitors with two distinctive important features: 1) a novel general scaffold which provides the correct ring distortion required to mimic both group-1 and group-2 neuraminidase transition-state; 2) further additional groups of suitable shape and size that extend the general structure and fill the cavity-150, with the aim of generate group-1 specific inhibitors. The objectives of the project will be achieved through the employment of multidisciplinary competences, in which the host institutions have enormous experience: design of carbohydrate mimics as inhibitors, libraries synthesis, virus like particles STD-NMR spectroscopy, biological evaluation and molecular modelling.This fellowship will ensure the opportunity for the applicant to be
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Genotyping using solid-state nanopores and Pepetide Nucleic Acid markers – a new tool for single-molecule molecular diagnostics' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

The rapidly decreasing costs of DNA sequencing have made the genomic sequences from thousands of pathogens broadly accessible. The utilization of this new knowledge in clinical practice, however, critically depends on the availability of new analytical tools and techniques that could quickly and efficiently detect the presence of specific genomic variants of pathogens. Some recent examples include the outbreak of H1N1 (Swine flu) and HIV-AIDS. Current approaches rely on costly and time-consuming Polymerase Chain Reaction (PCR), to achieve the specificity and quantity required by standard means of detection. Here I propose to develop a radically low-cost, single-molecule, genotyping method based on nanopore sensing of Peptide Nucleic Acids (PNA) markers. This method is designed to yield an extremely low cost, single-molecule detection of viral infections.Nanopores are emerging single-molecule sensors, where an electrophoretic force threads DNA or RNA biopolymers, into a nanoscale aperture made in a thin film. The threading process uncoils the biopolymers, as they move from one side of the film to the other. Molecules entering the nanopore occlude some of the free ions in the solution from the pore volume, thus permitting real-time electrical detection of the local cross-section of the biopolymer. We propose to develop this method to permit the rapid detection of sequence-specific PNA markers, known to invade double-stranded DNA and form bulges at the points of invasion. We recently showed that PNAs can be detected using tiny solid-state nanopores. To transform this discovery into a robust analytical tool, extensive studies are now required to critically improve the nanopore fabrication, the signal over noise of the measurements, and the biomolecular strategies for effici
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Synaptic mechanisms underlying neural coding in the retina during visual response' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

A formidable challenge for the visual system is to encode the statistical variability in the visual environment. For example, the vital statistics of contrast and luminance vary by several orders of magnitude within an image and during global changes in overall viewing conditions. The range of visual signals far exceeds the dynamic range of neurons in the retina.Traditional views dictate that during the visual contrast processing the retinal circuitry undergoes adaptation and thereby extends its dynamic range. This is intuitively appealing. However, recent studies have demonstrated an opposite form of plasticity – facilitation. Both adaptation and facilitation originate at the synaptic terminals of the bipolar cells. A combination of adaptation and facilitation might help to detect both an increase and decrease in contrast. However, the mechanisms underlying such plasticity and subsequent neural coding are largely unknown and my work will focus on studying these questions.This requires studying the properties of synaptic terminals of bipolar cells and that of amacrine cells which provide lateral inhibitory input. I shall use multiphoton microscopy to do in vivo measurements in the retina of zebrafish larvae. I shall monitor calcium signals and exo-and endocytosis of neurotransmitter vesicles at the synaptic terminals of both bipolar and amacrine cells under spatio-temporally different contrast illuminations. The calcium signals and vesicle activity will be simultaneously monitored using novel genetically encoded reporters of varying spectral properties. Secondly, I shall study the role of various neurotransmitters in modulating synaptic activity. Finally, I shall study how opposite forms of plasticity segregate into different layers of the retinal circuitry.Similar chal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'IOT- & Blockchain-Enabled Security Framework for New Generation Critical Cyber-Physical Systems In Finance Sector' (CRITICAL-CHAINS).

assistant: **Innovation**

Irregular and unaccountable transactions, cyber threats, non-user-friendly inefficient or impractical banking processes, complex contracting procedures and cumbersome financial market and insurance infrastructures constitute obstacles to European open market development. CRITICAL-CHAINS delivers a novel triangular accountability model and integrated framework supporting accountable, effective, accessible, fast, secure and privacy-preserving financial contracts and transactions to protect against illicit tranasctions, illegal money trafficking and fraud on FinTech e-operations.  This is an innovative cloud-based “X-as-a Service” solution stack including several layers: 1) Data integrity checking by involving financial institutions in the distributed Blockchain network; 2) Transaction and financial data flows  analytrics, modelling and mining; 3) Threat Intelligence & Predictive Modelling for Inter-Banks and Internet Banking, insurnace and financial market infrastructures; 4) Multilateral Biometric-based and Role-based Authorisation & Authentication; 5) Hardware Security Module (HSM) enabled Cyber-Physical Security, embedded systems & IoT security for secure access using Security-Privacy-Contexts Semantic Modelling; 6) Secure and smart use of Blockchain based on keyless signature infrastructure and hybrid (a)symmetric cryptography utilising truly random key generation. CRITICAL-CHAINS is to be validated within 4 case studies aligned with 3 critical sectors: banking, financial market infrastructures and the insurance sector. This will evaluate system reliability, usability, user-acceptance, social, privacy, ethical, environmental and legal compliance by scrutiny of the geo-political and legal framework bridging the European economy with the rest of the world. The Consortiu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Financing Energy Efficiency using Private Investments'.

assistant: **Objectives**

F-PI will help to reduce its transactional cost through on the promotion of Energy Efficiency projects by implementing a coherent work-plan and will execute a set of concrete actions. The concrete actions are focused on provision of technical assistance to private funds to boost their capital in energy efficiency. This technical assistance contains the design on standardized procedures to create and analyse portfolios as well as the definition of innovative financing alternatives, always having in mind the high degree of replicability. By the end of the project, F-PI will trigger €30m of investments into sustainable energy thanks to the successful execution of the planned actions as well as the definition of the proper standard procedures.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Embedded Intelligent Controls for Buildings with Renewable Generation and Storage' (ENCOURAGE).

assistant: **Concept**

The ENCOURAGE project aims to develop embedded intelligence and integration technologies that will directly optimize energy use in buildings and enable active participation in the future smart grid environment. The desired energy savings will be achieved in three complementary ways. Firstly, by developing supervisory control strategies that will be able to coordinate larger subsystems (HVAC,lighting, renewable energy generation, thermal storage, etc) and orchestrate operation of the numerous devices in such systems. The energy use will be optimized as a trade-off between occupants comfort, energy costs and environmental impact while considering people’s habits, weather conditions, characteristics of appliances, localgeneration and storage capacities and market conditions. Secondly, through an intelligent gateway with embedded logic supporting inter-building energy exchange. This brokerage agent will communicate directly with other buildings and local producers to negotiate possible use of the electricity produced locally in their premises. And thirdly, by developing novel virtual sub-metering technologies and event-based middleware applications that will support advanced monitoring and diagnostics concepts. Systematic performance monitoring will ensure the achieved savings are sustained over long period of time without being degraded by deteriorated performance of both mechanical equipment and the monitoring and control system itself. The primary application domains are non-residential buildings and campuses, but the project has relevancy also to residential buildings and neighbourhoods. This will be expressed through several demonstrators comprisingpublic and private office buildings, campus buildings, and private homes. ENCOURAGE aims to achieve 20%of energy savings t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Towards the prediction of stratospheric ozone iii : the partitioning of the noy components' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

The partitioning of reactive nitrogen species (NOy) in the winter stratosphere is only poorly understood. This limits the scientific reliability of predictions of the ozone layer over decades. This project analyses the NOy partitioning using data from the MIPAS balloon experiment, the ENVISAT instruments MIPAS andSCIAMACHY operationally provided by ESA, and retrieved to a higher degree by KARL, CSIC and UHB, which are compared to results of a variety of chemical transport models and data assimilation models. This comparison leads to improvements of the models involved which are passed to the CCM models of the DLRand ULAQ. Finally, these groups perform predictions of the ozone layer with a significant higher scientific reliability.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Measurement of Atmospheric Constituents by Selective Ion Mass Spectrometry' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

The major objective of this proposal is to further develop and refine a method for the simultaneous in-situ measurement of HNO3, N2O5 and ClONO2. It is the continuation of the MACSIMS I project (contract EV5V-CT92-0062), in which a balloon borne instrument was developed, which is based upon active chemical ionisation, using specially designed ion sources and a new magnetic double focusing mass spectrometer with simultaneous ion detection. The objectives of this project can be summarized as follows: 1. Continue the efforts to refine and finalise the balloon borne MACSIMS instrument, shown in figure 1 and based upon the combination of a flow tube equipped with special ion sources and a magnetic ion mass spectrometer, which allows the simultaneous measurement of stratospheric HNO3 and the sum of N2O5 + ClONO2 in the altitude region 15 to 30 km. Perform 2 balloon flights with the instrument and analyze the data. 2. Perform the required laboratory measurements of the ion-molecule reaction rates required for the analysis of the data obtained with this instrument. 3. Perform the necessary research and laboratory tests to develop a method for measuring ClONO2 and to adapt the instrument for this purpose. Modify the instrument accordingly and apply the method in the second balloon flight. 4. Investigate by laboratory testing and measurements the possibilities to extend the instrument for the measurement of neutral trace gases (HNO3, N2O5 and ClONO2) as well as ambient ions, so as to provide additional information about H2SO4 in the lower stratosphere.To reach the objectives some specific tasks are scheduled such as: - Developments and improvements for a balloon borne instrument - Realisation of 2 balloon flight and data analysis  - Ion molecule reaction measurements  - Study for