RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Origin of a cell differentiation mechanism and its evolution over 500 million years of life on land' (EVO500).

assistant: **Concept**

The evolution of the first rooting systems approximately 470 million years ago was a critical event in the history of life on Earth because it allowed the growth of complex multicellular eukaryotic photosynthetic organisms – plants - on the surface of the land. Rooting systems are important because they facilitate the uptake of every chemical element in the plant body with the exception of carbon. The root systems of thefirst land plants (liverworts) comprised a mass of unicellular tip-growing filaments (rhizoids) that grew from the plant surface into the soil. All root systems that evolved since then similarly comprise a system of tipgrowing filamentous cells located at the interface between the plant and the soil, indicating that the differentiation of filamentous root cells has been critical for root function for the past 470 million years. This proposal aims to characterize the origin and evolution of this essential cellular differentiation process. The proposed research is in three parts:First we propose to define the mechanism that controlled the development of the first land plant root system by identifying genes that control liverwort rooting system (rhizoids) development andcharacterizing their regulatory interactions.Second we propose to determine if the mechanism that controlled the development of the first landplant root system was inherited from algal ancestors.Third we propose to characterize the mechanism that controls filamentous root hair growth inArabidopsis in response to environmental factors, and determine if it is conserved among landplants.In combination, these experiments will define the genetic mechanisms underpinning the development and evolution of one of the fundamental developmental processes in land plants.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'A metabolism-based prognostic biomarker for prostate cancer'.

assistant: **Innovation**

Prostate cancer (PC) is the most prevalent tumour type among men. The fraction of patients that exhibit disease recurrence can reach 15% and they face an uncertain future, since this type of tumour is prone to resist to subsequent therapeutic strategies. Current guidelines for treatment of PC include prostatectomy or radiotherapy as first line therapy for localized disease, and chemical castration followed by chemotherapy for recurrent PC. The lack of capacity to identify therapy responders vs. escapers in PC is one of the sources for its important mortality. The challenge resides in providing clinicians with a robust and affordable biomarker that informs about the success of first line therapy in localised PC, and that allows them to employ more intensive therapeutic strategies in high-risk patients.The development of such prognostic tools is urgently needed, since western societies are facing profound changes in the major PC risk factors, including age and obesity. Last, but not least, the cost of treating PC will progressively impose strong pressure in the public health system. In addition, patients that fail first-line therapy can be enrolled in subsequent therapies for up to a decade, and given their advance age (PC predominantly presents in the sixth decade of life) they frequently present endangering and costly co-morbidities and secondary effects.MetaboMARKER, a novel biomarker developed in the framework of the ERC-StG-336343-CancerMetab and already protected under a European patent, is able to differentiate patients harbouring a PC that would progress and potentially metastasize, from those that exhibited a disease that would not likely be a risk to their lives. Thus, MetaboMARKER may contribute to more efficient diagnosis, improved treatments and better distri
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Rapid start up on quality management system implementation' (RAPID).

assistant: **Innovation**

The RAPID Project aims at developing a modular training product for QMS implementation for small and very small software companies constituted by a self-contained training package suitable for self-teaching and by a training course to be managed by teachers and supported by on-site supervisors.The project is constituted by two macro phases: the first one devoted to the preparation of a prototype of a training product followed by a test run in all the countries represented in the consortium to validate its content and format and its cultural independence; the second phase to take into account the feed-back collected during the test run to improve the product and its suitability to the users' requirements. Finally a set of three training actions based on the product will be run in the countries were the partners are based (Italy, France, UK and Germany) to consolidate the product and to reach a wider audience. A preliminary benefit awareness action was included to stimulate response by the target audience.ACTIONS1. Development of a modular self-contained training package, with self-teaching capabilities.The product implemented will include a number of innovative features:it will be an excellent and self-contained tool for the training of QMS implementers, with considerable potential for transferability of know-how within the company;it will be a generalised culturally and sectorally independent product for use in different European contexts;it will provide the necessary competencies and working aids (templates, reference materials, etc.) to fully support a quick QMS implementation;it will contain a module for benefit awareness actions targeted to senior management for them to understand, measure and appreciate the advantages of introducing QMS in the software development
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'A risk assessment of cryptosporidium parvum, an emerging pathogen in the food and water chain in europe.' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

This project will carry out research on-Cryptosporidium parvum, an emerging pathogen in water and food. The research will focus on the following areas:- a) Development of methods which can be used to isolate and detect C. parvum in food and water samples.b) Determination of the survival and infectivity of C.parvum in food and water.c) Development of procedures for control of C.parvum in food and water.d) A Risk Assessment of C.parvum in the food and water industry. water.e) A Risk Assessment of C.parvum in the food and water industry.1) Development of dedicated methods for the isolation and detection of C. parvum on food samples (beef and lettuce);2)Methods were developed and applied to the characterisation of Cryptosporidium isolates;3)Generation of the first reported surveillance date on C. parvum in food samples (salads, beef, and mussels);4)Generation of the first reported studies on the persistence of C. parvum in the food environment (Beef and lettuce);5)Assessment of the benefit of some control measures for beef, lettuce and water on C. parvum;6)Generation of the first risk assessment models for C. parvum in food samples (beef and lettuce) and recommendations on how risk could be reduced together with some recommendations on where future research should be directed
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Entangled Histories: The Historical Archaeology of Anglo-Indigenous Interactions in Colonial New England' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

This project explores Anglo-Indigenous interactions in colonial New England via historical archaeology. It draws upon archival data collected on both sides of the Atlantic Ocean along with archaeological data collected from three sites in North America. Together these data offer the opportunity to investigate the complexities of cultural continuity and change in colonial contexts, to examine the long-term outcomes of such interactions for both colonizer and colonized, and to bring these patterns into dialogue with broader debates concerning social identity, cultural change, and post-colonialism. In terms of career development, grant funds will be used to complete two major parts of this research: 1) the publication stage of the first phase and 2) the data collection stage of the second.The first phase concerns two archaeological sites: Brothertown, New York and Brothertown, Wisconsin. Each was home to the Brothertown Indians, a multi-tribal Christian Indian community who emerged out of the colonial tensions of eighteenth-century New England. Archival and archaeological data associated with each locale has already been collected, analyzed, and interpreted. Grant funds will be used for the publication stage of this portion of the research project and applied towards finishing a book on Brothertown archaeology and history slated for publication with the University of Arizona Press in late 2013.The second phase concerns the Cochegan Site in Montville, Connecticut, an interethnic site occupied by both Mohegan Indians and English settlers during the eighteenth and nineteenth centuries. The Cochegan Site marks a landscape of continual Mohegan-English interaction as it contains a sacred stone landscape—used by members of the Mohegan Tribe since the seventeenth century—and an En
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Energy Communities excellence Hubs: catalyzing energy innOvation ecosystems' (ECHO), addressing dissemination and exploitation.

assistant: **Impact**

The ECHO project seeks to establish Energy Community and innovative energy services Excellence Hubs in Türkiye, Greece, and Portugal. These hubs will accelerate the energy transition by fostering innovation ecosystems, building capacities, and empowering local stakeholders.  Employing a  quadruple helix model, the ECHO consortium engaged academia, industry, government, and civil society in a collaborative framework.To achieve this, ECHO will:- Create a networking platform for continuous stakeholder collaboration, enabling resource sharing, knowledge exchange, and the dissemination of best practices.- Implement an expert collaboration program, injecting cutting-edge knowledge and practices to enhance the project's R&I potential.- Deliver tailored training programs to develop hard and soft skills across the energy community value chain.- Establish diverse pilot projects demonstrating advanced energy services, technology transfer, and solutions to energy poverty. These pilots will emphasize either direct citizen ownership (Renewable/Citizen Energy Communities) or models where service providers own assets while upholding democratic principles and strong community engagement.ECHO's focus on sustainable, scalable, and inclusive Energy Communities aligns with EU energy transition goals. By bridging regional strengths and empowering stakeholders, ECHO will contribute significantly to a resilient and equitable energy landscape.


**Keywords:** Energy, community, widening, country, turkey, greece, portugal, innovation, services, demand response, p2p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Innovation Relay Centre North Rhine-Westphalia/Malta'.

assistant: **Objectives**

A joint IRC is proposed for NRW, Germany, and Malta. All actions target the consolidation of the ERA and are performedin this context. The overall target is 70 transnational technology transfer (TTT) agreements between European SMEs. Awork-plan of services for clients has been defined to promote TTT, i.e. actions for awareness raising, contact andassistance, e.g. company visits, technology audits, dissemination of technology offers/requests and transnationalevents. TOs generated from Community research results/EUREKA/ESA will also be integrated. Other tasks arestimulation of the capacity to adopt new technologies to create a future generation of IRC clients and signpostingof clients to other services offering assistance in matters linked to TTT. Second priority is services for colleagueIRCs aimed at supporting the improvement of the IRC network (provision of high-quality TOs/TRs, joint/multi IRC actions,e.g. joint brokerage events at major trade exhibitions within and outside the Thematic Groups, company missions, staffexchanges, provision of self-developed instruments to the network). Other actions in support of TTT/innovation includedevelopment/testing of new tools and models for the sustainability of the network beyond 2008 (e.g. working group oncharging policy for IRC services). Professional project management via appropriate operational procedures is an integralcomponent of the proposal. ZENIT´s and MCST´s joint proposal is based on the previous two-year mentoring agreement. The already establishedrelationship will permit the faster integration of Malta into the IRC network. However, as the IRC nodes in NRW and Maltahave different operating parameters (client base, regional/national technology transfer landscape, host structures) andare geographically far apart, ea
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Sustainable routes to shaped nanoparticles for selective catalysis' (NANOTUNE), addressing dissemination and exploitation.

assistant: **Impact**

The IIF project NANOTUNE aims to design novel palladium nanoparticle-based catalysts with tuned particle properties, and use them to control the selectivity of catalytic reactions. Changes to the support and addition of second metals will be used to tune the electronic properties of the nanoparticles. In addition, the particle shape will be varied using templating species such as organic ligands or changing the porosity of the support. By a combination of these techniques, it will be possible to design a catalyst to give high catalytic selectivity. The catalysts will be tested in the direct synthesis of hydrogen peroxide from hydrogen and oxygen, and chemoselective hydrogenation of substrates relevant to the fine chemicals and pharmaceutical industries. The reactions were selected on the basis of their relevance to the sustainability and economic development of Europe. A high-level understanding of the shape and surface chemistry of the nanocatalysts will be achieved by using advanced characterisation methods, including solid state NMR, X-ray synchotron techniques, high resolution TEM and Diffuse Reflectance Infrared Fourier Transform Spectroscopy (DRIFTS). Work in these areas will be in collaboration with the academic sector, both in the UK and Europe. The Fellow, Dr. Elena Cristina Corbos, is currently working in Japan, and will move to the UK and bring knowledge of the preparation of modified supports and DRIFTS catalyst analysis to the EU and to the host. The project has the potential to impact significantly on the future economic and sustainable development of the EU. Synthesis of catalysts with controlled properties is in line with the vision of the knowledge economy, which is a key part of the EU’s future prosperity. Increased selectivity of catalytic reactions w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'European multicenter study on familial dyslipidemic disorders in patients with premature coronary heart disease' (1994-1998) under Fourth Framework.

assistant: **Objectives**

- establish an extensive data-base of large European pedigrees with premature CHD and familial dyslipidemia (FD)- study in detail the genetic and biochemical background of the FDs- develop reliable diagnostic criteria with genetic and/or metabolic markersFamilial dyslipidemias (FDs) are major determinants of coronary heart disease (CHD). Approximately 50% of patients with angiographically documented CHD before the age of 60 years have FD. In contrast to familial hypercholesterolemia (FH), a relatively rare disease, the genetic and metabolic bases of these common disorders are mostly unknown, and therefore the diagnosis is often not applicable to clinical practice. We aim to collect a total of 300 large families with early CHD and dyslipidemia. The pedigrees are recruited from 5 centers located in the northern and southern parts of Europe. In the first phase of the study probands are selected from middle-aged patients undergoing elective coronary angiography with at least one-vessel disease, dyslipidemia and 5 eligible first-degree relatives. In the second phase the appropriate FD families are selected and included in the final phase, where complete pedigrees are examined with defined extensive clinical, metabolic and genetic studies. The proposed project has 8 top European centers devoted to analytical tasks. The metabolic and genetic studies will be coordinated and closely linked so that normal findings made in one field will support the other. We aim to dissect the molecular pathogenesis of these complex disorders by analysing complete metabolic pathways utilising both genetic and biochemical markers. When reliable markers for the common FDs are available, the identification of FD families with an increased risk for premature death will be an integral part of CHD prim
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Effective Management of Pests and Harmful Alien Species - Integrated Solutions', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

EMPHASIS is a participatory research project addressing native and alien pests threats (insect pests, pathogens, weeds) for a range of both natural ecosystems and farming systems (field crops, protected crops, forestry, orchards and amenity plants).The overall goal is to ensure a European food security system and the protection of biodiversity and of ecosystems services while developing integrated mechanisms of response measures (practical solutions) to predict, to prevent and to protect agriculture and forestry systems from native and alien pests threats. The specific objectives are the following:1.Predict, Prioritize and Planning: pest management challenges and opportunities will be evaluated according to stakeholder-focused criteria and through pathway analysis;2.Prevent: practical solutions for surveillance in different pathways to enhance preparedness will be provided to end-users, and monitoring tools following outbreaks and eradication will be developed;3.Protect: practical solutions for managing native and alien pests in agriculture, horticulture and forestry will be developed, their technical and economic feasibility will be demonstrated and their market uptake will be enhanced. 4.Promote: a mutual learning process with end-users will be developed, and the solutions identified by the project will be promoted through training and dissemination.The project is in line with EU policy framework (Plant Health Dir. 2000/29/EC, EU Biodiversity strategy to 2020, Dir. 2009/128/EC on sustainable use of pesticides, Roadmap to a Resource Efficient Europe) and its future developments (Reg. on protective measures against pests of plants, Reg. on Invasive Alien Species). The project is not focused on a single management systems but the plant/pest ecosystems dealt with are trea