RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Prefabrication of roof integrated PV systems' (PRIDE), addressing dissemination and exploitation.

assistant: **Impact**

One of the main barriers that impede large scale application of PV in buildings is that the realisation of high-tech building integrated PV (BIPV) systems is poorly tuned to the regular on-site low-tech building process and therefore too time consuming and expensive. PRIDE aims at the improved integration of PV in the regular building process through joint industrial prefab PV roof development by building industry, PV industry and utility sector, being the logical next step, now that the advantages of building integration have been proved and have appointed a key role to the, building sector. PRIDE will lead to cost reduction, quality improvement and enhanced market acceptance of BIPV, by builders and utilities. First experiments in the Netherlands, show that industrial prefabrication is technically feasible and has a good cost and time reduction potential. In addition the concept is very promising as a result of the fact that there is a general trend towards industrial prefabrication in the building industry. The following innovative aspects can be mentioned: . Strong collaboration between PV industry and building industry; . Precabling and premounting of PV systems prior to installation on the building site; . Use of industrial prefabrication technology for BIPV; The activities of PRIDE will start withthe definition of a program of requirements based on the knowledge and experience of the project partners and additional information on state-of-the-art and future developments in industrial prefabrication. With the programme of requirements, a number designs will be developed both for southern and northern European climates and optimised with respect to price/performance ratio. The selected designs will be prototyped and tested on constructional, building physical and e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Unveiling the Origin of Non-Thermal Emission in Galaxy Clusters through Advanced Numerical Simulations in the LOFAR Era' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The origin of relativistic particles that generate the observed synchrotron radio emission in the Intra-Cluster-Medium (ICM) of galaxy clusters is one of the most mysterious problems in our understanding of these complex systems. Recent advances from observations and theory suggest that turbulence, generated during cluster-cluster mergers, has a major impact on the acceleration of relativistic particles in the ICM. We propose a 2-year project to develop advanced cosmological numerical simulations to model self-consistently the acceleration of cosmic-rays in the turbulent ICM and the resulting non-thermal emission on cluster scales, radio halos. Our simulations will provide a significant step forward in the field and yield direct predictions for radio telescopes. They will shed light on the origin of the observed radio emission and the important issue of the interplay between thermal and non-thermal components in galaxy clusters. Upcoming european projects like the LOFAR telescope are expected to discover thousands for radio halos and are going to directly benefit from our project. This promises a golden age of discoveries in this field and make our proposed project particularly timely.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Cloning and characterization of genes encoding putative fission yeast kinetochore components' (1994-1998).

assistant: **Concept**

In all eukaryotes the centromeres are essential for separation of chromosomes into dividing cells. The centromere DNA forms together with several proteins a large complex called the kinetochore. The role of the kinetochore is to mediate contacts with the microtubules and motor proteins that pull the chromosomes to opposite poles of the mitotic and meiotic spindles. The centromere DNA sequence has been defined in fission yeast but the protein components are hitherto unknown. The aim of this project is to clone and characterise the genes which encode trans-acting components of the fission yeast kinetochore. To this end six temperature sensitive lethal mutations called cspl -6 (centromeric suppressors of position effects) and six nonlethal mutations (csp7-12) have been isolated. These are good candidates for kinetochore mutations because they affect the in vivo accessibility of the centromere DNA and cause chromosome loss.The corresponding genes will be cloned and sequenced. The immunolocalisation of the gene-products will be investigated.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Neuroendocrine Seeds of Obesity' (NEURO-SEED).

assistant: **Concept**

Obesity prevalence is dramatically increasing worldwide. The hypothalamus seem to be a pivotal brain structure in reversing obesity, as hypothalamic activation by incretin-based therapies (IBT) reduces body weight by 25%. However, the detailed functioning of the human hypothalamus in obesity remains unknown.Therefore, my overarching objective is to characterize hypothalamic structure and function in obesity. I will collaborate with clinical obesity experts at the University of Copenhagen and a pioneering MRI research team at Brigham and Women’s Hospital.The project includes three Work Packages (WPs), each addressing a gap in current state-of-the-art knowledge:WP1: Impact of IBT on hypothalamic signalingHypothesis: IBT partially or fully normalizes meal-induced hypothalamic signaling to reverse obesity.Sub-objective: Map how long-term IBT affects hypothalamic signaling to the rest of the brain in a large randomized controlled trial of youth with obesity.WP2: Exploring the Impact of Oxytocin on Hypothalamic Structure and FunctionHypothesis: Oxytocin reduces radiological indicators of hypothalamic inflammation associated with obesity and improves hypothalamic function.Sub-objective: Characterize hypothalamic structure and function in obesity and map the effects of four weeks of intranasal oxytocin treatment.WP3: Hypothalamic Responsiveness to Incretin HormonesHypothesis: Hypothalamic responsiveness to incretin hormones is impaired in obesity.Sub-objective: Map the responsiveness of the hypothalamus to incretin hormones in people with obesity compared to people without obesity.The output of this project will elucidate key neurobiological mechanisms underlying obesity and inform the development of sustainable strategies to treat and prevent obesity. It will also facilitate c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Characterization of signalling and physiologic roles of the class II PI 3-kinases'.

assistant: **Innovation**

Phosphoinositide 3-kinases (PI3Ks) are a conserved family of lipid kinases that generate lipid second messengers inside cells. Mammals have 8 isoforms of PI3K, divided in three classes (I, II and III). The focus of research has thus far almost exclusively been on class I PI3Ks, which have been implicated in cancer, inflammation and diabetes and which are the target of ongoing drug development efforts in Pharma. Very little is known about the other PI3Ks, in particular the class II PI3Ks, which comprises the PI3K-C2alpha, PI3K-C2beta and PI3K-C2gamma isoforms. This research proposal aims to delineate the physiological roles of PI3K-C2alpha and PI3K-C2beta, their integration in signalling by tyrosine kinases and G protein-coupled receptors, the lipid products they produce in cells and their downstream intracellular signalling pathways. The focus of these studies will be on metabolic signalling and cancer. For this proposal, I have access to two new unpublished mouse lines with inactivating mutations in the PI3K-C2alpha and PI3K-C2beta genes, which will be subjected to whole-organism studies and phenotypic screening, in parallel to cell-based studies using various techniques, including new proteomic techniques which have been developed in the Host Laboratory. The Host Laboratory uses an innovative mouse gene targeting strategy whereby PI3K isoforms are inactivated in a ""drug-like"" fashion. This is achieved by the replacement of the wild-type gene by a germline knock-in allele that encodes a kinase-dead protein, mutated in the ATP-binding site. The proposed work is expected to uncover the biological roles of an evolutionary conserved signalling module. This work also has potential implications for the ongoing drug development in the PI3K area where inhibitors often also h
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Concentration and threshold phenomena in random graphs and hypergraphs' (RandomHypGra).

assistant: **Concept**

The central theme of this proposal is the enumeration of large structures obeying a family of local constraints.  There are numerous well-studied instances of this general problem in combinatorics, probability theory, and statistical physics.  We propose to study a variety of interrelated open problems, spanning extremal and probabilistic combinatorics, Ramsey theory, and large deviation theory, whose unifying theme is the distribution of copies of a given graph in large random graphs.The first part of the proposal revolves around the 'infamous' upper tail problem for subgraph counts in random graphs, which has seen spectacular progress in the last few years.  We propose to advance the combinatorial approach introduced in our recent work on a special case of the problem to solve this problem completely and make progress on several related questions.The second part of the proposal discusses the global structure of 'sparse' subsets in hypergraphs.  We propose to prove a far-reaching generalisation of the hypergraph container theorem that provides a useful description of the family of all 'sparser-than-average' sets.  We plan to use it to resolve the lower tail problem for subgraph counts in the uniform random graph and to prove a sparse analogue of the counting lemma for regular graphs.The third part of the proposal concerns the enumeration of independent sets in hypergraphs with cardinalities below the threshold for appearance of global structure.  In order to obtain precise asymptotics for the number of such sets, we propose to extend the cluster expansion method from statistical physics to models with non-pairwise interactions.The fourth part of this proposal deals with thresholds for fundamental extremal and Ramsey properties of random graphs and hypergraphs.  We prop
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Developing Multi-Core Silicon-Based Quantum Processors'.

assistant: **Innovation**

Silicon technology was the key to transforming classical computing into a massive industry. Could it play a similar role in quantum computing? Silicon qubits have several attractive features and can rely on a mature industry that has already mastered the intricacies of scaling. However, while scientific advances in silicon qubit technology have been encouraging, progress has been modest on the commercial front. This is the consequence of a rift between the techniques of the semiconductor industry and the requirements of quantum computers. At Siquance, we close this gap thanks to a ground-breaking semiconductor approach: Fully Depleted Silicon On Insulator (FDSOI) technology. FDSOI technology enables the fabrication of high-quality qubits in a scalable and reproducible manner. Now, we advance these developments to the market. This project aims at delivering an FDSOI-based quantum processor demonstrator with a novel 4X4 multi-core architecture.


**Keywords:** Quantum computing, Silicon qubits,  quantum technology, semiconductor technology
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Punishment as Communication: Transgressors’ Interpretation and Understanding of Punishment' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Punishment is ubiquitous. We discipline children when they misbehave, and we demand even harsher sanctions for criminal offences. Punishment is thought to serve a communicative purpose: Through punishment, victims and third parties seek to send various “messages” to transgressors (e.g., condemning the wrongness of the act and imploring them to reform). But are these messages effectively delivered and understood by transgressors? And does the interpretation of a punitive message have the desired effects on the transgressor?To answer these questions, this research examines (a) the types of messages transgressors receive through punishment (why they think they are being punished), and (b) transgressors’ reactions to them (e.g., perceived fairness, experienced remorse). Further, it explores (c) the features of a punitive message that influences how the message is interpreted by transgressors. The research will be built on a theoretical framework that integrates knowledge from three distinct fields: legal philosophy, social psychology, and behavioural economics. The specific hypotheses deducted from this framework will be tested in controlled experimental lab studies as well as in a court setting.The insights from this research will be informative to all disciplines interested in criminal justice and punishment. First, this research will develop our theoretical understanding of punitive procedures and their effects. Second, it has important implications for how we should deliver punishment to enhance justice outcomes, whether in the context of formal legal proceedings or informal sanctions.The quality of the research will be strengthened by access to exceptional research facilities and expertise at the host university, and interdisciplinary collaboration with scholars both w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Search for physics beyond the Standard Model at the high intensity frontier, from new physics to spin-offs. A trilateral Europe – United States – Japan effort.' to be submitted under Horizon Europe.

assistant: **Abstract**

BEYOND will explore elusive aspects of the Standard Model (SM) of particle physics and search for new physics, covering a wide range of research topics across different areas of fundamental interactions, from electroweak to strong interactions. It will exploit particle accelerators, as well as shared experimental techniques and search strategies. The observation of neutrino oscillations established a framework consistent with the mixing of three neutrino flavours in three mass eigenstates, along with small mass differences. Experimental anomalies suggest the existence of sterile neutrino states, which participate in the mixing but do not couple to the SM gauge bosons. Lepton mixing and massive neutrinos also provide a potential gateway to deviations from the SM in the lepton sector, including Charged Lepton Flavour Violation. Several low-energy aspects of quark-gluon interactions remain a challenge, such as the mechanism of color confinement, which accounts for 99% of the mass of ordinary matter in the Universe, as well as the equation of state of ultradense matter. Astrophysical observations and particle physics anomalies indicate the existence of Dark Matter (DM), prompting major efforts to the search for galactic DM and potential signals at particle accelerators.We are leading the development, construction, commissioning, operation and data analysis of cutting-edge experiments aimed at answering these fundamental questions. These endeavors require extensive knowledge sharing and technological advancements, with potential spin-offs not only in fundamental physics but also in commercial applications, offering market opportunities for non-academic participants. Through extended exposure to cutting-edge research environments at world-class laboratories, including PSI and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'A Performance History of Morris Dancing: Music and Musicians, 1550-1700'.

assistant: **Objectives**

Morris dancing is a historical dance form which has been practiced in an almost uninterrupted tradition since c.1458 in the British Isles and on the European continent. This origin date for the English tradition has been traced in royal court records by historian John Forrest, who describes Morris dancing as being deeply connected to public celebration in early modern England. Forrest presents an extensive picture of historical references to Morris dancing as it survives in primary source documents. What is lacking, however, is a more practical examination of Morris dancing and its accompanying music, as it was performed during the early modern era. Due to a recent resurgence in the popularity of Morris dancing in the UK, modern musical publications focus on dance tunes only from the eighteenth century or later. There is, consequently, a lack of knowledge amongst current practitioners about music used for Morris dancing in the period 1550-1700. This is a time when Morris dancing was deeply connected to public life, as dancers and their accompanying musicians were supported by rural parishes for fundraising events during regular festivals that aligned with traditional harvest-time and farming practices. This project will have a focus in performance alongside traditional research outputs for dissemination, to share the work with local creative industry groups and the general public. The research will trace and document music used for Morris dancing in sixteenth and seventeenth-century England and its relationship to the wider European tradition. It will explore the ways in which the accompanying music was performed through musicological and practice-based research techniques including archival and textual study and rehearsal on period instruments. This study will provide
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Global Response Against Superbugs and Pathogens' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The emergence and spread of AMR are major socio-economic problems in Europe and worldwide. The epidemic of antibiotic-resistant pathogens, particularly in healthcare settings, is associated with increased costs in terms of economic losses and human suffering, as well as increased rates of mortality and morbidity. Moreover, the United Nations has recently reported that the diversity and abundance of environmental antimicrobial resistance genes are also modulated by climate change, as increased temperature acts as a driver of AMR by modulating bacterial growth, metabolism, mutation rates, and horizontal gene transfer. The GRASP project will address the AMR crisis at several different levels. We will develop different synergistic approaches to target AMR including chemical biology of essential enzymes and virulent factors, drug repurposing, and phage therapy. Moreover, to understand the emergence and spreading of AMR, we are particularly interested in understanding how DNA repair defects can drive the emergence of AMR in the clinical strains of Mycobacterium and Helicobacter pylori. Finally, we are also interested in developing concrete case studies with more applied interest e.g in AMR stewardship, and the development of new computational and AI-based models as well as experimental devices to study the emergence of AMR in Nature and clinics.The highly complementary GRASP consortium includes specific expertise provided by leading European, North American, and African partners that will together build synergistic interactions to address the global health crisis. The private sector will actively provide supervision, mentoring, and various expertise in lab automation, nanofabrication, scientific instrumentation, AI methods, and computational biology. GRASP will thus provide r