RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Chemical Engineering of Natural Killer Cells for Cancer Immunotherapy'.

assistant: **Objectives**

Our immune system evolved to protect our bodies from different invaders and to fight against infections and diseases. Immune cells use sophisticated ways to detect and destroy abnormal cells, while sparing our own cells. Unluckily, cancer cells often develop sneaky tricks enabling them to evade this protecting machinery and to survive and proliferate. Immunotherapy, an emerging concept of treatment, aims to employ the power of immune system to fight cancer by boosting or reeducation of immune cells. One of the approaches, the adoptive cell transfer therapy, especially in the form of chimeric antigen receptor (CAR) cells, has shown an unprecedented success in the treatment of certain types of cancer. CAR cells are genetically modified immune cells engineered to recognize and kill cells with specific cancer antigen. Unfortunately, production of genetically modified CARs is problematic, inefficient, time consuming and therefore, associated with high costs. New approaches enabling production of modified immune cells more effectively, faster and cheaper could therefore change the way the therapy is used. Within this proposal, we will explore the potential of an innovative approach for production of chemically engineered immune cells and their application in immunotherapy. In particular, we will employ our technology based on combination of metabolic engineering and subsequent biocompatible chemical labeling to produce an antibody modified natural killer (NK) cells that we will investigate in cancer killing experiments. We will perform a side-by-side comparison of our technology with the traditional CAR-NK cells both, in vitro and in vivo, to evaluate the pros and cons of both approaches. Finally, in collaboration with our Tech Transfer Office, we will present the technology
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Application of tailored fibre placement technology in integral composite structures for ultra-lightweight space applications' (2014-2020).

assistant: **Innovation**

The project is intended to investigate feasibility of applying the tailored fibre placement (TFP) technology for design and manufacturing of composite structural parts for space applications.One structural element commonly used in load carrying structures for space is the strut. Struts attachment fittings have been impossible to manufacture with lightweight FRP (fibre reinforced polymer) materials due to limitations of the FRP manufacturing technologies. State-of-the-art is therefore a CFRP tube with bonded metallic fittings.With the recent evolvement of TFP technologies in terrestrial applications, Space Structures is convinced that it is possible to manufacture and qualify fully integral CFRP struts, including CFRP fittings, for space applications.The TFP strut product targets 3 areas of concern to our customers, the space industry:• Ultra-lightweight, due to replacement of metallic fittings, with CFRP and maximum efficiency carbon fibre orientation and continuity along the load paths• Cost and manufacturing time reduction, due to cheaper material, manufacturing automation and simplification of processes• Environmental friendly. Smaller footprint because the energy intensive manufacturing and chemical bonding of metallic fittings is removed from the process. Ultra-light structures also reduce the propellant consumption during launch of space vehicles.By using the most innovative technology for CFRP manufacturing, all aspects of the product are improved and consequently the worldwide commercial potential is immense, ultimately redefining the state-of-the-art.The feasibility study in phase 1 will investigate if this type of structure can be designed to meet space requirements and will conclude with the manufacturing of a prototype. A feasibility report and a business pl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'European innovation partnership network promoting operational groups dedicated to forestry and agroforestry'.

assistant: **Concept**

Innovation is a key priority for the private forestry(F) and agroforestry (AF) sector, and nationally/locally funded EIP-AGRI Operational Groups (OGs) can play a key role in driving innovation at the EU level. However, the results of the OGs in F and AF have not been disseminated to all EU countries because the various local/national OGs have not been linked to the experiences of other countries and the knowledge generated has only been shared locally. In order to disseminate the knowledge generated by the OGs in F and AF to all EU regions, FOREST4EU will set up multi-actor innovation interregional transversal Hubs dealing with 5 innovation topics ('Wood mobilisation', 'Forest adaptation to climate change', 'Improving approaches, models and tools for sustainable forest management and ecosystem service provision to improve economic, environmental and social benefits for rural areas', 'non-wood forest products', 'Agroforestry') to facilitate interregional transfer of knowledge generated by the OGs. FOREST4EU will collect, share and disseminate knowledge related to innovations from F and AF OGs. This will be done by providing tailored and understandable dissemination materials accessible through existing platforms, as well as capacity building materials developed according to identified regional needs and transferred to where the innovation can be applied. FOREST4EU will also discuss and present the benefits of OGs relevant to the Green Deal to EU policy makers. In addition, FOREST4EU will establish connections with policy makers working with CAP and innovation at the local level, particularly in countries where OGs dealing with F and AF are not funded, to promote new initiatives and a greater geographic balance between different EU regions.


**Keywords:** Forest, Agrofor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Integration of Environment Concerns into Agriculture', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

Specific Objectives:1 Methodological developments to integrate spatial information layers at different scales to estimate land cover change in rural areas as a tool for the implementation of a sustainable EU's agricultural policy;2 Development of a methodology for deriving a European landscape characterization and spatial stratification. Test the feasibility to implement pressure indicators over European landscapes;3 To make available JRC's expertise and competence when further research is needed for understanding the linkages between agriculture and the environment in particular for the spatial component. To provide access to scientific and technical references for agri/environmental geo-spatial databases (in particular, further development of the pan-European river and catchment DataBase in support to environmental reporting activities of DG Env and EEA).Anticipated milestones and schedule:Results and first draft model of Corine Land Cover profiles (Nov 2003). Results of the methodological research on landscape characterization (Nov 2003). Version 2.0 of 1:250K River and Catchment DataBase (Oct 2003).Planned Deliverables:1.1. Methodology to analyse the components of land cover type disagreement coming from data format (vector-raster), location, scale and time (change). Selection of a test site, identification of data sources and data acquisition (area frame surveys and images). Report on data sources and acquisition;1.2. Estimates of fine scale land cover profiles of CLC. Report with and first draft model of CLC profiles;2.1. Review of landscape typologies and necessary input data in Europe, test methodologies for deriving a European landscape typology. Report on landscape typologies and data sources available;3.1. Creation of the Agri-Env web site for disseminating i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The water recycling bio toilets' (RecycLoo) targeting Horizon 2020.

assistant: **Abstract**

WeCo offers an ingenious and innovative waste-water treatment system that enables a closed loop flush for toilets. This solution will answer the needs of potential customers having no water or no sewer connection, or willing to limit their water consumption. As such, this provides a new solution for outdoor public toilets (for municipalities, theme park operators…), for mobile toilets (for construction sites, events…), for indoor toilets in non-sewered new or renovated buildings, and for train toilets.WeCo has clear assets to enter this broad potential market, with a scalable solution that is the only one fostering user acceptance. Besides, WeCo partnership strategy ensures its access to the targeted market. WeCo has thus initiated key collaborations with Alstom (access to train market) and another major listed French company of mobile toilets market for construction sites. WeCo expects to become a leader of the European market by 2023, with an annual turnover of € 11,9M representing a 20% share of the serviceable addressable market. This growth will be followed by a global extension toward Asia and Africa, where the WeCo solution will definitely have a humanitarian dimension.The SME-Instrument Phase 1 grant will finance the feasibility study of the WeCo system, in particular for the indoor toilets and the mobile toilets segments.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Symmetry Principles in Nature' (SPIN).

assistant: **Concept**

Symmetries have traditionally played a very important role in our understanding of physics, both classical and quantum. As we move towards the next frontier of defining a quantum theory of gravity, it is clear that they will continue to play a predominant role. The current project is aimed at obtaining a comprehensive  understanding of the dynamics of strongly coupled quantum systems, exploiting various symmetry properties that one expects on physical grounds. Specifically, the aim is to come up with effective descriptions of a wide class of quantum dynamics in gravitational and non-gravitational theories using the holographic gauge/gravity correspondence.One of the primary strands of the proposed research involves a critical examination of gravitational theories with higher spin symmetry. We will investigate the phase structure of such theories, the nature of gravitational solutions and notions of classical geometry in the presence of the enlarged gauge symmetry. Using appropriate generalizations of the gauge/gravity correspondence we will try to give gauge invariant characterizations of these concepts and further explore how such higher spin theories can be realized in string theory. A related strand of research concerns a deeper understanding of the gauge/gravity correspondence itself,  with focus on figuring out how collective behaviour of strongly coupled field theories leads to the emergence of extra symmetries, such as local diffeomorphisms in the dual description. Along the way we will also develop effective descriptions for collective dynamics of strongly coupled quantum degrees of freedom, both in and out of equilibrium.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Plaspro' in the context of a Fourth Framework call.

assistant: **Objectives**

The importance to reduce development times is expressed day by day. Mainobstacle for further reduction is the poor availability of prototypes andpreseries parts which can be treated like production parts when being tested. Aspeific large demand exists for parts of high class" or reinforcedthermoplastics like PC, and PA. The proposers want to reduce this gap through 3axis: 1. Improve laser sintered thermoplastic parts by further post treatment,e.g. infiltration with suitable resins. 2. Cast a castable resin into siliconerubber moulds, which sets into a thermoplastic material. 3. Improve thecapabilities of tooling methods involving RP by applying composite structuresand simplify the mould design. Rapid Prototyping Techniques will be basis tonew and improved process chains giving especially SMEs a strong tool to facethe increasing competition from the USA and the far East."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Interferometric Evaluation of Glacier Rheology and Alterations (INTEGRAL)'.

assistant: **Objectives**

The general objective of the INTEGRAL initiative is to promote an advanced observation technology for the unsupervised detection, precise measurement and variation analysis of ice motion / deformation on large European glaciers based on the complementary use of radar interferometer and interferometer altimetry, and to support natural exploration, social-economic activities and subsequent surveys in the glacier environment with equivalent Theological models and appropriate information on the glacier regime in the form of new value-addedINSAR products. Our polar idea is to enhance the detailed ness, accuracy, integrity and versatility of glacierinterferometric models yet without involving complex process artifices and to demonstrate new utilities of differential radar interferometer to operational users working with SAR data from post-operational, operational and upcoming systems such as E-SAR, ERS, SRTM, ENVISAT, RADARSAT, ALOS and CRYOSAT.The INTEGRAL project is, thus, focused on methodological aspects and empirical issues of glacierinterferometry, and major attention is paid to:- Design of enhanced algorithms and program tools for processing and fusing SAR interferograms, both air- andspaceborne, with radar altimetry data aimed at precise encoding and upgrading the information content of glacier theological models.- Application of phase-gradient, offset-tracking and transferential techniques to the detection and interpretation of glacier activity, numerical modelling have the glacier regime, and assessment of main tendencies in the state of land ice resources in response to climate change.The results obtained by different approaches will be intercom pared and verified during field surveys in several European arctic and alpine test areas. The output products will be app
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Food science, technology and engineering - European Joint Doctorate training towards knowledge, skills and mobility' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The objective of the proposal is to train 8 early stage researches (ESR) in an innovative, international PhD program, to become top-class specialists and professional leaders, highly demanded in the job market, ready to introduce innovations and manage advanced research. The completion of the training programme will provide ESRs with appropriate knowledge, skills and awareness of the science-business reality, crucial for scientific and/or commercial based research projects.The training objectives will be achieved by participation in:-specialized courses, to gain: a) knowledge in food science, microbiology, malting and brewing technology, b) experience in using high-tech analytical equipment, c) managerial and business skills (generic skills, industrial economics, project management, research design and data analysis);-an international research project team, using the facilities of multi-institutional consortium;-academic and industrial internships.Consequently, ESRs will be awarded a double doctoral degree in food science and/or engineering. The main goals of the research are: 1)development of innovations in malting and brewing technologies (to reduce demand for energy) and new protocols for yeast preparation;2)verification of their impact on the quality and stability of the products;3)acquiring new scientific knowledge on formation and release of staling aldehydes.The consortium of top class universities, institutes and industrial partners, with an on-going history of co-operation, will provide an outstanding opportunity for young, ambitious and brave researchers to realize their potential. The academic organizations involved (University of Agriculture in Krakow PL, University of Copenhagen DK, University of Nottingham UK, University of Ghent BE, Technische University
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Mechanisms of Evasive Resistance in Cancer' (MERIC) targeting Seventh Framework.

assistant: **Abstract**

Cancer is a major health problem due to the failure of current therapies to effectively eradicate the disease. Alternative signaling pathways compensate for a therapeutically targeted pathway, a process referred to as 'evasive resistance'. The identities of the alternative signaling pathways and functional interconnections that underlie evasive resistance remain widely unknown. We propose to integrate cutting-edge clinical, molecular, and computational sciences to understand the signaling defects that allow tumors to evade therapy. With its synergistic, interdisciplinary approach, the proposed project is, to our knowledge, unique in Europe and possibly worldwide.Within the framework of rigorously designed clinical studies, a clinician will provide basic research scientists with diseased tissue isolated before therapy, during treatment or at the time of tumor progression. The tissue, chosen based on medical importance, accessibility to repeated sampling, and ethical considerations, will be from hepatocellular carcinoma. Tumor tissue will be obtained by needle biopsy and snap frozen to preserve in vivo properties. The basic research scientists and a computational biologist will determine, characterize and model the underlying signaling defects. Importantly, using longitudinal clinical samples in combination with mouse and cellular HCC model systems, we will seek to define treatment-related changes in cell signaling that allow tumors to circumvent therapy. This process will be iterative such that changes in treatment strategies will again be monitored in the same patient or experimental model. Insights gained will be used (i) to understand mechanisms of evasive resistance, (ii) to identify novel drug targets and predictive biomarkers, and (iii) to rationally design persona
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Aceuropean molecular biology laboratory, grenoble outstation' to be submitted under Fifth Framework.

assistant: **Abstract**

Description:The European Molecular Biology Laboratory (EMBL) Grenoble Outstation collaborates closely with the European Synchrotron Radiation Facility (ESFR), the world's leading third generation source, in providing state-of-the-art synchrotron radiation facilities to European structural biologists. The intensity and high collimation of the ESRF beams is unparalleled permitting crystallographic data to be measured on weakly diffracting samples, notably micro-crystals and very large complexes that cannot be performed elsewhere.The beamlines at the ESRF available for macromolecular crystallography, particulary protein crystallography, are a fourendstation macromolecular crystallography undulator beamline (ID 14 EH 1-4), a bending magnet (BM14) and undulator bemaline (ID29) optimised for MAD crystallographic experiments and a microfocus undulator beamline designed for microcrystals (ID 13). All beamlines are equipped with fast-readout CCD detectors. An important additional factor provided by the Grenoble Outstation is the combination on one site of active biochemical and molecular biololgy laboratories in close proximity to the best synchrotron radiation facilities, which are open to all LifeSciences users of ESRT. This provides the ideal environment for visitors whishing to collaborate on challenging structural biology problems, to prepare and characterise their samples and to be trained in the use of synchrotron facilities.Application:Details of the beamlines operated by the Joint EMBL-ESRF Structural Biology Group (JSBG) are available on: http://www.esrf.fr/expfacilities/jsbg/jsbgbeamlines.html.Details on how to obtain EU support for use of ESRF public beamlines are available on: http://www.embl-grenoble.fr (click on Access to ESRF beamlines). There are two deadlines p