RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Setting up research intensive clusters across the EU on characterization of polymer nanostructures' (NAPOLYNET) targeting Seventh Framework.

assistant: **Abstract**

NaPolyNet is a 36-month project involving 16 partners from 10 European countries. The objectives are: 1. to network at regional, national and international level with experts on the characterization of polymer nanostructured materials in the field of packaging, textiles and membranes, bridging the gap between scientific and engineering approaches for the improved understanding of the structure-performance correlation in polymer devices; 2. to facilitate transnational access to important and unique equipment and to train young scientists and SMEs technologists; 3. to harmonize the work necessary for new standards in the field of characterization of polymer nanostructures for packaging, textiles and membranes. NaPolyNet will also focus on latest findings for managing the safety implications of polymer nanostructure along the life-cycle of those products. The activities are grouped into 7 work-packages (WP): After setting up the procedures for managing the project (WP1), the team will map the competences in the different fields of characterization of polymer nanostructures and will set up an European Open Laboratory (EOL) open to outside the consortium partners (WP2) incorporating the best and novel characterization methodologies and expertises. The EOL will be the base of the demonstration activities planned in WP3 and for the activities reported in WP4 that aims at making soon available experimental and theoretical strategies and routines in developing stage at the EOL location. This will allow average trained users of equipment for thermal, structural, morphological, mechanical characterization to produce reliable data on nanostructured materials and correctly interpret them. An International Workshop is planned on processing-structure-dynamics and properties of polymer
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Adaptation and biodiversity in the spanish populations of pinus sylvestris'.

assistant: **Innovation**

To study adaptation and biodiversity in the Spanish populations of Pinus sylvestris I propose:(1) Q_st VS F_st. (2) Correlation of quantitative traits vs geographical variables (3) SSR-inferred relatedness for heritability estimation under common garden conditions and in the nature.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'European SMEs challenge in the MOBIle telecommunications TECHnologies' (MOBITECH) targeting Fifth Framework.

assistant: **Abstract**

This proposal outlines a 18-months programme to boost the SME participation in the 5th Framework Programme according to the ETI guidelines, with the goal to enhance their presence in the mobile telecommunication sector. After an overall state-of-the-art of the new technology offer, and an analysis of the market demand, both present and in trends, Mobitech will establish direct relationships with a large number of European SMEs to evaluate their technology needs to better reply to the market requirements, becoming more innovative and more competitive. The process to reach this objective will be based on the promotion of the 5th FP actions and in assisting SMEs in their participation in 5th FP actions. Mobitech will focus on mobile telecommunication market, ensure SMEs involvement to the project through the European Federation of High-Tech SMEs and consider as a priority the field work directly in contact with SMEs.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'AIR TRAFFIC MANAGEMENT AND COMMUNICATION OVER ATN/IPS' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Air-to-ground communication technology is at the heart of the end-to-end air traffic management concept, which requires the global integration of current, future, and emerging communication networks. The present ATMACA (Air Traffic Management and Communication over ATN/IPS) project addresses an innovative solution enabling effective, seamless, interoperable air-to-ground datalink communication technologies and digital flight monitoring and management environment through aeronautical telecommunication (ATN) based on internet protocol suite (IPS) within all domains of flight. In this frame, ATMACA project aims at supporting “air-ground integration and autonomy” innovation flagship in the Strategic Research and Innovation Agenda (SRIA) presenting the strategic roadmaps to achieve SESAR phase D “Digital European Sky” in European ATM Master Plan 2020 edition. ATMACA proposes a beyond the state-of-the-art IP-based datalink communication solution by introducing an application-layer mobility management for ATN and enabling commercial of-the-shelf equipment. It will also provide a next generation human machine interface (HMI) which will process higher quality data, enable interactions with the existing and future aeronautical applications and services, and meet the needs of end-users. ATMACA solution will be validated based on real-time simulations and real-time monitoring tests by considering relevant applicable SESAR key performance areas and indicators as well as industry standards. The consortium consists of a balanced mixed of universities and industrial partners (an air navigation service provider, an airline and a research and consultancy firm specialized in HMI design) to ensure the achievement of the project objectives.  ATMACA project’s outcomes will deliver a robust a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Uncovering the Regulators of Cellular Plasticity by Direct Reprogramming'.

assistant: **Concept**

Cellular reprogramming has revolutionized stem cell biology by allowing the generation of stem cells, progenitors, or somatic cell identities with small combinations of transcription factors (TFs). Currently, the limited understanding of how these different degrees of plasticity are established and maintained keeps on hold the application of reprogrammed cells in the clinic. With the RePLASTIC project, I propose to uncover novel regulators that define degrees of plasticity and control cell identity, with an interdisciplinary approach merging the fields of gene editing, stem cells and immunology.  I will develop an innovative platform to evaluate the impact of gene knockout across the process of cell reprogramming in human cells, comparing multiple cell conversion scenarios: pluripotency, multipotency (hematopoietic stem cells) and unipotency (dendritic cells). For this, I will carry out a CRISPR/Cas9 knockout screening coupled with next-generation sequencing using custom-designed sgRNA libraries targeting TFs, chromatin regulators, and RNA modifiers. After sequencing, I will determine the molecular targets that are relevant by comparing the three reprogramming systems. Genes involved in cell conversion will be defined as regulators of plasticity, and top hits will be validated to study their molecular mechanism and role. Certainly, RePLASTIC will open new research avenues on the basic principles of cellular plasticity and provide ground-breaking technologies that may contribute to immunotherapy, regeneration and cancer. I will pursue this project as an incoming researcher supervised by Dr. Filipe Pereira (Lund University, Sweden). During my stay, I will acquire hands-on expertise in cutting-edge techniques: direct reprogramming, hematopoietic/immune cells, gene editing,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Integrated SAfety Benefit Estimation tooL for 2-wheeLErs'.

assistant: **Concept**

The traffic accidents, with 2wheelers like bicycles, motorcycles and mopeds, represent 23% of total road fatalities in EU. Even though until now there is no clear understanding of the mechanisms of injury of such vehicles. The lack of knowledge and uncertainties of the complex dynamics of 2wheelers accidents is limiting the advancement of protective equipment for them. This is a reason that most of the efforts for development of protective equipment were focused only on helmets and protective clothing and not on devices that would prevent the riders’ impacts with other vehicles or the environment i.e. for the development of motorcycle airbags rather contradictory results came out for their safety benefit attributed from the authors to the overestimation of neck-injuries from the dummy used in the crash-tests. Further electric 2wheelers and new types of innovative ultra-light electric vehicles that offer sustainable urban mobility are developed or already introduced in the market with similar concerns for their safety as the traditional 2wheelers. These types of vehicles are expected to increase their fleet due to their advantages in urban mobility, increasing also their proportion in traffic injuries if their safety concerns are not addressed.The goal of this project is to develop deeper understanding of the injury mechanisms of motorcycle accidents and a new framework for the assessment of safety of all 2wheelers. This project will be realized with focus on motorcycles but the developed methodology, and tools will be applicable to all other 2wheelers.The major expected results of this project are: (a) an ambulatory motion capture system, (b) new knowledge on motorcyclist’s kinematics, (b)  development of a biofidelic numerical active human model, (c) better understandi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Sustainable exploitation of biomass for bioenergy from marginal lands in Europe' (SEEMLA), addressing dissemination and exploitation.

assistant: **Impact**

The aim of the SEEMLA project is the reliable and sustainable exploitation of biomass from marginal lands (MagL), which are used neither for food nor feed production and are not posing an environmental threat.The main target groups are regional authorities and public or private owners of MagLs, who can provide knowledge on land availability and are responsible for managing these. Furthermore foresters, farmers and the civil society affected by transformation of MagL into energy crop plantations are important cooperation partners for the project’s success.The initial challenge of the project is to define MagL. In order to achieve high yields on the MagL the goal is to develop and optimize cropping systems for special sites. The project focuses both on existing plantations of energy crops on MagL and on the establishment of new plantations on MagLs. General guidelines and manuals shall attract and help relevant stakeholders as well as piloting shall prove the feasibility of SEEMLA results. The first scenario will enable the assessment of good practice and the refinement of current practices, making them more sustainable (environmental, economic, social). The second approach will transfer good practices to underused MagL. The project will focus on three main objectives: the promotion of re-conversion of MagLs for the production of bioenergy through the direct involvement of farmers and foresters, the strengthening of local small scale supply chains and the promotion of plantations of bioenergy plants on MagLs. Moreover the expected impacts are: Increasing the production of bioenergy, farmers’ incomes, investments in new technologies and the design of new policy measures. The project team is balanced between scientific and technical partners as well as national and regional
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'A CONCERTED ACTION TO CONSTRUCT GENERIC DATABASES OF RE-ENTRY AND BYSTANDER EXPOSURES TO PLANT PROTECTION PRODUCTS, AND DEVELOP PREDICTIVE MODELS' (1994-1998).

assistant: **Concept**

A primary objective of this proposal is to construct a generic European re-entry database of the monitored exposures associated with re-entry by workers into areas where crops have previously been treated with plant protection products. This exercise will allow generic Transfer Factors (also known as Transfer Co-efficients) for specific crop/re-entry activity combinations to be derived. A predictive model will be developed that will use Transfer Factors to predict worker re-entry exposure.A second primary objective is to construct a generic European database of bystander exposure to plant protection products, and to develop a predictive model.A third objective is to use previously generated studies to evaluate the efficacy of exposure mitigation measures.The final objective is to update and expand the existing European predictive operator exposure database and to refine the predictive operator exposure model (the EUROPOEM database and model).The group will establish criteria for acceptability of re-entry and bystander exposure data. Existing re-entry and bystander studies will be collected and generic databases will be constructed. The group will develop models for the prediction of bystander and re-entry worker exposure. In addition, new studies of operator exposure (e.g. studies carried out since the EUROPOEM project began and studies carried out in member states that have only recently joined the EU) will be collated and used to update the EUROPOEM operator exposure database, filling data gaps. This will allow refinement of the EUROPOEM model to produce an improved basis for predicting operator exposures and potential hazards. The available exposure data will be critically reviewed in order to evaluate the efficiency of exposure mitigation measures, including protect
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'THE ENZYMATIC MACHINERY OF HUMAN MITOCHONDRIAL DNA MAINTENANCE' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

SUMMARYMitochondria are required to convert food into usable energy forms and every cell contains thousands of them. Unlike most other cellular compartments, mitochondria have their own genomes (mtDNA) that encode for 13 of the about 90 proteins present in the respiratory chain. All proteins necessary for mtDNA replication, as well as transcription and translation of mtDNA-encoded genes, are encoded in the nucleus. Mutations in nuclear-encoded proteins required for mtDNA maintenance is an important cause of neurodegeneration and muscle diseases.  The common result of these defects is either mtDNA depletion or accumulation of multiple deletions of mtDNA in postmitotic tissues.Research in my laboratory will elucidate the molecular mechanisms and regulation of mitochondrial DNA replication in human cells. We will establish how mtDNA is packaged into nucleoprotein complexes, a.k.a. nucleoids and establish how these nucleoids are selected for mtDNA replication. We will elucidate the molecular mechanisms by which specific mutations in the mtDNA replication machinery affect mtDNA maintenance and cause human disease.Mitochondrial dysfunction is not limited to rare, genetic disorders, but also associated with age-associated common diseases as well as with the normal aging process. I will use my biochemical insights in combination with mouse genetics to address the hypothesis that increased mtDNA mutation load may be an important cause of normal aging.My specific aims will be:Aim 1. To define how initiation of mtDNA replication at OriH is regulated.Aim 2. To identify and characterize regulators of mtDNA replication.Aim 3. To characterize the structure and function of the mtDNA nucleoid in DNA replication.Aim 4. To address the mitochondrial theory of ageing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Sub-seasonal to Seasonal climate forecasting for Energy' (S2S4E) targeting Horizon 2020.

assistant: **Abstract**

Large scale deployment of renewable energy (RE) is key to comply with the GHG emissions reduction set by the COP21 agreement. Despite cost competitive in many settings, RE diffusion remains limited largely due to its variability. This works as a major barrier to RE’s integration in electricity networks as knowledge of power output and demand forecasting beyond a few days remains poor. To help solve this problem, S2S4E will offer an innovative service to improve RE variability management by developing new research methods exploring the frontiers of weather conditions for future weeks and months. The main output of S2S4E will be a user co-designed Decision Support Tool (DST) that for the first time integrates sub-seasonal to seasonal (S2S) climate predictions with RE production and electricity demand. To support the dissemination of climate services, a pilot of the DST will be developed in two steps. The first will draw on historical case studies pointed as relevant by energy companies - e.g. periods with an unusual climate behaviour affecting the energy market. The second step will improve probabilistic S2S real-time forecasts built up into the DST and assess their performances in real life decision-making in these companies. This process will be co-designed with consortium’s partners which represent different needs and interests in terms of regions, RE sources (wind, solar and hydro) and electricity demand. Besides the partners, S2S4E will engage other users from the energy sector as well as other business areas and research communities to further explore DST application and impact. As a result, DST will enable RE producers and providers, electricity network managers and policy makers to design better informed S2S strategies able to improve RE integration, business prof
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Fully integrated technology for predictive diagnosis of sepsis'.

assistant: **Innovation**

This proposal features a novel and inexpensive, plug-and-play ultrasensitive immune-PCR fully integrated system (lab-on-chip) that will help with early diagnosis of sepsis or toxic shock syndrome caused by pathogenic bacteria Saphylococcus aureus and Streptococcus pyogenes. Sepsis kills 5.1 millions of people annually; it has up to 26% mortality and rapid progression. S. aureus and S. pyogenes colonise ~50% healthy individuals, and cause common diseases such as tonsillitis, skin and deep tissue or medical implant infection, which sometimes progress to sepsis. Biomarkers that predict of S. aureus and S. pyogenes-caused sepsis are bacterial toxins, superantigens. S. aureus causes most deaths from infectious diseases in high-income countries. This situation is exacerbated by spread of multiple antibiotic resistant S. aureus (MRSA) in the community and hospitals. Superantigens are commonly found in the serum in the absence of bacteremia. It is hence not appropriate to detect them by PCR of the toxin-coding DNA sequences. The key to our innovation is detection of superantigen protein using novel DNA-containing detector nanorods. Binding of the detector particles to the analyte will be quantified via the nanorod DNA. This strategy (immune-PCR) combines immunodetection with sensitivity of PCR to achieve ultrasensitive detection. The system devised in this action will be a prototype for a novel class of devices for ultrasensitive detection of wide array of molecules, including explosives, hormones, or chemical pollutants. The affordable all-in-one plug and play design will allow use in the general practitioner’s office (point of care), at home, or even in the war zones or disaster areas.Development of fully integrated point-of-care lab-on-chip prototype will require multidiscip