RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Safety regulation of Transgenic Crops: Completing the Internal Market ?' under Fourth Framework.

assistant: **Concept**

The commercial potential of a agricultural biotechnology, especially of transgenic crops, is becoming central to strategic choices for enhancing economic competitiveness, while encouraging sustainable development. These choices involve social, economic and ethical perspectives on how 'risk' and 'benefit' should be defined. The primary means available for handling those concerns has been safety regulation; under such pressures, it has become difficult for regulatory procedures to fulfil their aims of helping to overcome internal trade barriers and public unease.This study will inform policy processes and decisions on the most appropriate form of EU Safety regulation for transgenic crops, so as to find a more consensual basis for their commercialization in the EU internal market.Our aims relate to those of the ELSA programme, in particular:I) to clarify how ethical, social and legal issues are taken into account in regulatory decisions for transgenic crops, so that the procedures may be improved;ii) to promote an informed dialogue among the key players in public debates on how to regulate transgenic crops;iii) to suggest how regulatory expertise could be broadened to encompass public and scientific concerns;We will disseminate our results through publications, workshops.The main contractor will co-ordinate a European network of studies by partners and subcontractors in ten European countries. The project has 6 main aspects, which overlap somewhat, as they do in actual practice:I) diverse regulatory boundaries across member states, as regards regulatory procedures for food safety, pesticides, food labelling;ii) normative judgements in agriculture, as regards which potential effects of transgenetic crops are deemed acceptable;iii) risk-assessment research, particularly wher
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Wireless Test fixtures to Measure the Dielectric Properties of Materials in RF'.

assistant: **Concept**

RF characterisation of dielectric materials is increasingly an important scientific and commercial activity insofar as even if a very significant effort of the RF community has allowed the development of reliable characterisation solutions, it remains that these techniques rely on RF test fixtures that is heavy to implement, expensive, with a limited field of use (type of materials, frequencies, resolution) and therefore not adapted to the ever-increasing needs of companies, most of which have neither advanced skills in the field nor the equipment to implement these characterisation methods. Indeed, the explosion of the IoT and thus of wireless communication solutions has given rise to the need for companies in a wide range of sectors (not only specialised in electronics and even less in RF) to have a better understanding of the RF performance of the materials they use or wish to use for the fabrication of their devices. For cost or supply reasons, these companies are forced to use materials that are not necessarily suitable for RF (or simply whose RF characteristics are not known), typically plastics that under the same name may in fact have very different dielectric characteristics, particularly in terms of losses, and therefore pose a problem. The idea of the project is to demonstrate the technical and economic viability of a new solution for RF characterisation of dielectrics. This approach breaks with the techniques currently used insofar as it will make it possible to be able to characterise a larger number of materials (plates, solids, liquids, powders, etc.) at a lower cost compared with current solutions. We hope that in a few years this solution will become the reference solution for a large number of companies that until now have not access to these test fixt
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'CARBON FIBRE PRODUCTION VIA LOW ENERGY MICROWAVE ABSORPTION'.

assistant: **Objectives**

CARBOWAVE deploys alternative heating sources i.e. plasma or microwave heating to replace conventional heating in energy intensive industries. The conversion of microwave electromagnetic radiation to heat relies on a high dielectric loss tangent (DLT). This is of importance as many of Europe’s most energy intensive industries utilise low dielectric loss raw materials. Carbon fibre (CF) which is used to produce carbon fibre reinforced polymers (CFRP), is produced from poly(acrylonitrile) (PAN) which exhibits a low DLT (0.007). CF is designated as a strategic material for Europe as it is deployed in many crucial sectors which underpin Europe’s future energy security e.g. in manufacture of light weight wind turbines for wind energy generation; in manufacture of light weight automobiles and electric vehicles for a more energy efficient Transport sector; and similarly for a more energy efficient Construction sector. Hence, CARBOWAVE will have vast economic and environmental impact. Europe dominates the advanced carbon materials market supplying 37% of the global market, which is projected to grow at a CAGR of 5.8% to reach US$7.9 billion by 2027. Currently, the industry uses large amounts of electricity and natural gas to generate the heat necessary for conversion of PAN to CF (100–900 MJ per one kg of CF produced), limiting the industrial use of CF to high end and expensive applications. In this context, CARBOWAVE aims to drastically reduce the energy consumption, carbon emissions and production cost of CFs. This in-turn will radically transform the construction, wind energy and EV industries. CARBOWAVE will achieve this through development of two alternative heating sources; an atmospheric plasma for stabilisation of PF, and a radically new susceptor induced microwave heat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'AGPs roles in Arabidopsis fruit development' (FruitAGPs) targeting Horizon Europe.

assistant: **Abstract**

By 2050, the global population is projected to reach approximately 9.7 billion, adding significant pressure on the world's food production systems. This global population increase will require a substantial improve in food supply, including fruits, which are essential for human nutrition. To understand the fundamental molecular mechanisms related to the fruit development is extremely important for increasing crop productivity and high-quality fruit and seed production. Furthermore, the knowledge acquired in this process will be important for developing fruit crops resilient to changing climates, meeting this demand sustainably and ensuring food security. FruitAGPs aims to provide new insights into the role of Arabinogalactan Proteins (AGPs), cell wall glycoproteins crucial for plant growth and development, and their putative transcriptional regulation in fruit tissues providing crucial knowledge about their functions in these tissues. This will be achieved using a combination of cutting edge genetic, proteomic and molecular biology approaches in Arabidopsis thaliana.  Both the host laboratory and researcher stand to benefit from FruitAGPs, as it bridges two distinct molecular research fields focused on the same developmental process: fruit development.


**Keywords:** Arabidopsis; Arabinogalactan Proteins; Fruit development; Transcription Factors
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Assessment and implementation of Agriculture and Life Science Universities’ first Gender Equality Plans in widening countries' (AGRIGEP), addressing dissemination and exploitation.

assistant: **Impact**

Gender inequality is a major barrier in the R&I area that limit the capabilities and capacities of research and education institutions. Although major efforts to reach gender equality (GE) in R&I have been made in many areas of the world, there are still prominent inequalities in the widening countries. Across the EU, the development of Gender Equality Plans (GEP) intends to address the problems at RPOs; however, the variability in capability, capacity, and expertise hinder the efficient implementation of the institutional GEPs. Additionally, there are specific GE issues within certain fields of study at research and education institutions. In this context, GE issues in the Science, Technology, Engineering and Mathematics (STEM) fields are well known and specific action plans have been developed. Within STEM, agriculture and life-science focused RPOs face very similar problems, but they lack sector-specific measures and mitigation plans. Furthermore, in agriculture, a large GE sector-specific imbalance exists in developing countries where a relevant proportion of RPOs’ international students come from. The AGRIGEP project, with the joint efforts of six consortium partners, aims to i) perform a responsible assessment of widening RPOs' current status on GEP implementation, ii) improve capabilities through intensive capacity building, and iii) develop and implement an agriculture and life-science targeted GEP with sectorial specific measures and strategies. These results could lead to long-term institutional reforms. Additionally, this project will work to establish the inclusion of GE issues within the RPOs’ educational system and professional training of students. The realisation of these objectives and the implementation of inclusive GEPs will enhance the inclusiveness,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'New prECision thErapieS for uveal melanoma (targeting the Gαq/GNAQ oncogenic Signaling cIrcuiTrY)' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

G protein-coupled receptors (GPCRs) represent the largest family of cell surface proteins involved in signal transmission. Nearly 30% of human cancers harbor mutations in GPCRs/G proteins. Activating mutations in GNAQ and GNA11 have been discovered in 90% of Uveal Melanoma (UM).UM is the most common primary cancer of the eye in adults and to date there are no effective treatments. 50% of UM patients develop metastatic disease, which is refractory to current chemotherapies leading to patient death within a year. Prolonged Gaq signaling leads to the activation of YAP, a transcriptional co-activator regulated, necessary for UM growth. GNAQ stimulates YAP through FAK. Inhibition of FAK reduces UM growth,leading FAK to be a potential therapeutic target for UM. In UM, the particular Gαq–regulated pathways that when overactive can render FAK inhibitor(FAKi) ineffective, as well as what feedback mechanisms should be targeted to optimize therapeutic responses to FAKi are still unknown. I will use a panel of GNAQ-driven UM cells and perform a genetic screen using the Cancer Signaling Toolkit to discover molecular determinants of sensitivity or resistance to FAK inhibition. Signaling candidates and screening hits discovered will be prioritized and their biological impact in UM growth and FAKi sensitivity will be evaluated. To increase FAKi activity and reduce therapy resistance, I will also investigate whether co-targeting candidate GNAQ-effector and FAKi resistance pathways will synergize with FAKi, resulting in UM cell death. Finally,I will explore the mechanism of UM cell death by co-targeting. My studies will reveal new targeted(precision) strategies for multiple Gαq-driven pathological conditions in cancer The project will be supervised by Dr. Gutikind and Dr.Martini two expe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Development of a rapid prototyping system for body panels and shells' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

The industrial objective of the proposed RTD is to provide SME manufacturers of GRP and pressed steel panels with a rapid prototyping process, enabling them to reduce the costs and elapse time for prototyping vehicle body parts. This will enable SMEs in the car, truck, bus and rail sector supply chains to integrate further into their customers' design process, helping them to acquire preferred supplier status, by adding value to their service, rather than compete on price alone. This will also strengthen their competitive position against lower cost base component suppliers from the Pacific Rim and former Eastern Bloc counties and create the opportunity to export an entirely new form of prototyping technology into a global market. To achieve this, a number of technical objectives must be met, relating to the development of an RP system that incorporates the following elements: A fixed position, two part epoxy spray head. A compact 6 axis workpiece manipulator, mounted on a linear table. A novel programmable, conformable spray pad, constructed from pneumatic valves and pins, beneath a silicon membrane. Software for the generation of a 'patchwork' surface pattern, composed of sub-sections that integrate to form a complete surface for the component to be prototyped. The code for which would be based on the architecture and algorithms already used to generate build files from 3D CAD geometry, for existing RP processes. Software for the generation of NC code to integrate the motion of the 6 axis manipulator and the conformable pad, to enable edge blending between the surface model's sub-sections.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Alhambra 2000' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

Alhambra 2000: Joint Mathematical European-Arabic Conference arises within European Mathematical Society (EMS) as an opportunity to meet mathematicians from all European and Arabic cultures. The Spanish Royal Mathematical Society (RSME) offers its support and heads the organisation of this conference in Granada in collaboration with the Centre International de Mathématiques Pures et Appliquées (CIMPA).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on '“Intoxicated by turpentine”: An Olfactory History of Painting (1750-1939)'.

assistant: **Concept**

“Intoxicated by turpentine.” When Marcel Duchamp so described the painters of his time, the avant-garde artist was not only criticizing a traditional way of thinking about the materiality of art, he was also modernizing a commonplace of medical discourse as well as a recurring and significant motif in the French commentary on the arts. Investigating historically the stereotype of “the smell of paint,” this research project seeks to underscore the important role of olfaction in the material history of art and in the historical conceptions of the art of painting in France from the mid-18th century to the first half of 20th. At the crossroads of art history and history of the sciences, this research will describe how medical concerns about the smell of paint significantly influenced the making and the composition of colors as well as the size and organization of the painter’s studio, consequently affecting the social status of the artist and, ultimately, the critical discourse on art, which often used the smell of a painting in metaphors expressing an aesthetical judgment. Thus, from the creation of a painting to its reception, the frequent references to the smell of paint unveil a hidden aspect of the history of art that will be illuminated through this analysis of a variety of historical sources, including, in particular, medical works, technical treatises on painting, industrial archives, art criticism, satirical drawings, etc. Finally, this historical research on the smell of a painting will be applied to the creation of a pedagogical tool aimed at the museum-going public. It will present the historical evolution of the painter’s studio through the smells of the painter’s materials. This sensory experience of the materiality of painting aims to embody art history, prov
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Edu-Arctic – Innovative educational program attracting young people to natural sciences and polar research' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The general objective of the EDU-ARCTIC project is a cross-country adaptation of innovative practices in science education in Europe. EDU-ARCTIC will provide a custom-designed large-scale program to strengthen schools’ science education. EDU-ARCTIC will use innovative online tools for interactive open-access available for everyone to link Arctic research and school education in Europe. The program is dedicated to young students in the age of 13 to 20 and their teachers. The program will be based on 5 main components: 1) Broadcasts (webinar transmissions) of online lessons from polar stations on natural sciences and polar research related to important societal challenges. The content of webinars will be adopted to school curricula at various levels (regional, national and European); 2) “Polarpedia” – an online developing encyclopedia with scientific expressions, educational resources and dictionaries in at least 5 national European languages; 3) Arctic competitions for European pupils cooperating with their teachers, in which prize winners will be able to participate in polar expedition; 4) Monitoring system: all schools in Europe will be invited to participate in a program based on monitoring of phenological observations in schools’ surroundings, a web based portal for registrations and access to accumulated data. 5) Teachers workshops and trainings. The novel educational programme elaborated within EDU-ARCTIC will give European pupils the opportunity to get insights in Research and Innovation process by access to (two-way communication) lecture transmissions from polar stations, participation in arctic competitions and environmental monitoring in their own surroundings. The interaction with real-time scientific work will contribute to increased interest among young boy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Influence of hypoxia in the tumor microenvironment on the adaptive immune response and cancer immunotherapy' (2007-2013).

assistant: **Innovation**

The tumor microenvironment determines many of the hallmarks of cancer. Stromal components and malignant cells dialogue and mutually change their functional responses. Tumor infiltrating lymphocytes (TILs) are a prominent feature of solid tumors, whose presence has correlation with a better survival in cancer-patients. However TILs are severely restrained in their ability to tackle tumors as a result of immunosuppressive mechanisms. This proposal is based on the hypothesis that low levels of oxygen availability in solid tumors induce profound changes on the adaptative immune response mediated by HIF-1α and HIF-2α transcription factors. Research objectives include: 1) To study TILs behaviour under hypoxia 2) To explore the molecular mechanisms underlying the observed changes, and importantly, 3) To evaluate the impact of these changes for different immunotherapeutic strategies (monoclonal antibodies, adoptive transfers, and drugs targeting the hypoxia pathway).The state-of-the-art technical approaches to address these objectives include cutting-edge two-photon in vivo imaging to study the immune response inside hypoxic tumors, and unique-in-the-world transgenic mice to unravel the HIF-1α and HIF-2α pathway importance in T cells.This project will enable a more rational design of anti-tumor immunotherapies and could help to explain disease recurrence and identify potential targets for therapeutic interventions.