RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Interactive Robotic Social Mediators as Companions' to be submitted under Sixth Framework.

assistant: **Abstract**

State of the art research emphasises the important role of play in child development as a crucial vehicle for learning about the physical and social environment, the self, and for developing social relationships. IROMEC targets children who are prevented from playing, either due to cognitive, developmental or physical impairments which affect their playing skills, leading to general impairments in their learning potential and more specifically resulting in isolation from the social environment. IROMEC will investigate how robotic toys can provide opportunities for learning and enjoyment. The developed robotic system will be tailored towards becoming a social mediator, empowering children with disabilities to discover the range of play styles from solitary to social and cooperative play. Robustness, dependability as well as plug&play" operation of the robot system are specially addressed.<br/>A novel framework for robotic social mediators will be developed and evaluated by means of a dedicated robot setup in the context of therapy and education. The research focus of IROMEC is on the user oriented definition of appropriate play scenarios, development of evaluation methods, definition of robot behaviours and interaction modes, and finally a system development compatible with safety as well as market demands. Outcomes of IROMEC will demonstrate on a conceptual, experimental, and technological level the novel role of a robotic mediator in therapy and education of children who are usually prevented from play. IROMEC aims to set the basis of a new product and service in the area of special education and thus is in line with the focus of the given strategic objective.<br/>IROMEC brings together 8 multidisciplinary partners from pedagogy, psychology, ICT and robotics. This cons
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Precision drug REPurpOsing For EUrope and the world' in the context of a Horizon Europe call.

assistant: **Objectives**

Here we, a group of long-standing collaborators in innovative drug repurposing, propose to build REPO4EU, a comprehensive European/global platform for validated precision drug repurposing open to stakeholders for information, multimedia training, matchmaking and cooperation. Drug repurposing reduces the time and costs of drug development but is often serendipitous and less effective than classical drug discovery. Both, discovery and repurposing, suffer from the same knowledge gap that diseases are mechanistically not understood and treated symptomatically in an imprecise manner. Our team of world-leading scientists overcome this by breakthroughs in advanced bioinformatics and artificial intelligence (AI) on real-world big data to redefine diseases in a mechanism-based manner. Patients are still identified by symptom, but stratified according to causal mechanism, the endotype. Trials are small, precise, innovatively designed, prioritising, in coordination with regulators, payers and investors, patient-defined outcomes with high safety and operational excellence. This revolutionary new era of medicine will allow unprecedented efficacy and cost-effectiveness. The promiscuity of small molecules and recently expanded knowledge of protein structures are exploited by cheminformatics and deep learning to repurpose drugs beyond their original target. At any level of the development chain, even for classic projects, REPO4EU provides expertise and matchmaking for freedom-to-operate, intellectual property, reformulation and value-creation, specialised in drug repurposing. Within 5 years, REPO4EU will establish a first-in-class coherent and innovative web-based platform for safe and efficient drug repurposing for all types of high unmet medical need indications to all European resea
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Development of a clean and energy efficient cutting system for the 12 millions tons of granite blocks yearly processed in enlarged EU' to be submitted under Seventh Framework.

assistant: **Abstract**

The stone industry is of strategic importance for the EU economy, particularly its Southern member states including Italy, Greece and Portugal. A large proportion of the 60 million tons world production can be attributed to the EU countries, representing an estimated market of 20 billions of Euro, and of this 81 % is produced in the Southern European countries. Although the prospects for the sector future development appear to be promising, there is a number of problems, which have to be addressed in order for the sector to remain competitive and maintain its leading position in the global market. These problems are particularly relevant when considering stone processing and particularly granite slab production, being faced by low productivity, huge quantities of waste material, high energy consumption and environmental management of wastes produced. There is therefore a need for a new concept of granite slabbing machine with high energy saving per square meter, a low environmental impact, high versatility in work programming, high productivity, high quality surface finishing, as well as reduction in foot print. The solution to this need represents a huge opportunity for the SME participants and more in general for the competitiveness of the overall stone filiere, employing some 500,000 people in 60,000 companies, whose majority has less than 50 people. In this framework, the main objective of the project is to address a number of scientific barriers for the development of an innovative stone slabbing machine which is based on a set of diamond wires operated vertically and not horizontally, thus reducing energy consumption and overall machine foot-print, while enabling the processing of both regular and irregular sized blocks. The system do not use grits as for the curr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'ENHANCED ON-STREET PARKING MANAGEMENT SYSTEM' (FastPrk-2), addressing dissemination and exploitation.

assistant: **Impact**

The migration of the global population to urban areas has strained the resources of cities worldwide. To address these challenges governments are turning to Smart Cities to provide sustainable infrastructure that meets the needs of citizens. The smart city industry is projected to reach 1.56 $ trillion by 2020. Smart city initiatives are focussing on smart parking systems to enhance regulated parking spots with occupancy sensors that provide additional features & services to parking management companies as well as drivers by reducing time spent looking for parking, traffic and CO2 emissions. Monitored parking spaces will be a global emerging market by 2020 when 1% of on-street parking spaces will be controlled. The European Parking Association estimates that there are 12M parking spaces available for smart parking (in European cities with more than 20K habitants). As a result, they estimate that there are an additional 190M spaces likely to become regulated in the near future, equalling a huge potential market for Fastprk-2 in Europe alone. Considering the competitors & the time-to-market we aim to manage 60M parking spaces for 2019. FastPrk-2 is an innovative full featured smart on-street parking solution, featuring enhanced services resulting from almost 100% accurate occupancy sensors & a system architecture that provides cutting edge HW-based sensor technology & SW-based tools that optimize transport management through innovative applications that analyse diverse parking related data, minimizing maintenance costs and operational processes. Worldsensing is a cutting edge tech company, a market leader in innovative wireless solutions, & a pioneer in IoT technologies, with a strong executive & advisory team, as well as the strategic investors Cisco, Mitsui and FJME. Wo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Palaeocloud Reconstruction Project' to be submitted under Horizon 2020.

assistant: **Abstract**

Clouds are a key component of global climate. Alteration to simulated cloud in climate models has large surface temperature effects, yet we cannot validate model predictions for the future against observations. Reconstructions of major patterns in mid-Piacenzian Warm Period (mPWP) cloud can provide critical verification data from an analogous past climate to assess the cloud prediction ability of state-of-the-art climate models, however there are no known biological proxies for cloud in deep-time.The aim of PReP is to develop proxies capable of reconstructing past cloud and to use them to establish a global cloud database for the mPWP, for testing cloud model prediction performance.The development of biological proxies for cloud characteristics in deep-time will be pursued in two streams: statistical methods – testing cloud as an emergent property of existing palaeoclimate estimates and testing the extent to which existing palaeoclimate schemes can be expanded to predict cloud – and experimental methods – investigating a novel proxy for cloud through leaf micromorphological variation under cloud-mimicking light schemes. The methods will be used to reanalyse existing data for mPWP sites with the aim of establishing a global palaeocloud dataset for model verification within the Pliocene Modelling Intercomparison Project.My experience in multiproxy palaeoclimate analysis, and Pliocene palaeoclimate specifically, combined with the interdisciplinary expertise at the University of Leeds in Pliocene climate modelling and applied statistics, and at the National University of Ireland, Galway in palaeobotany, will create the optimal intellectual environment to deliver the aims of the project. The experience of my host as a supervisor and mentor for early career researchers, and t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Highly Adaptible Rubber Isolation System' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

BE95-1258 Highly Adaptible Rubber Isolation System Rubber based devices employed in base isolation have been used in bridge engineering for over 40 years. The limited damping capacity reduces the field of application when dynamic excitation becomes critical. This project focuses primarily on bridges and viaduct structures but with extensibility to buildings compromising new design and retrofitting. The research project is aimed at developing abilities to control the dissipation capacity of rubber devices. The importance of adaptability is observed through the definition of measures and elements for a rubber isolation system supported by design rules, which can be applied to different site conditions. The result will provide an inexpensive isolation system considering implementation and maintenance costs. The investigation in new design of rubber devices will result in high energy dissipation in the range of 15% to 30% equivalent damping. Through probabilistic methods, parameters and properties will be quantified in terms of reliability of the isolation system and therefore, in consequence, an optimized solution strategy is possible. Sophisticated software will be developed enabling the analysis of the rather complicated mechanical model. A shaking table test will give especially important feedback of the installed rubber isolation system under real conditions. Important hot spots in terms of quality for production will be identified as well as sensitivities for implementation accuracy will be quantified.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Promyelocytic leukemia protein (PML) outside the tumor: a new player in the control of inflammation' (PML), addressing dissemination and exploitation.

assistant: **Impact**

Local sterile inflammation arise in many pathologic states, including several diseases of the nervous system as brain stroke, neurodegenerative diseases and epilepsy. The persistent and de-regulated inflammatory response sustains these neurological pathologies worsening their prognosis. Different molecular players, as NLRP3 and P2X7 have been shown to contribute to the progression of these illnesses triggering the release of IL-1β and recruiting cellular components of the immune response at the neurodegeneration site. Consistently, brain penetrant P2X7 antagonists are clinically used to treat epilepsy and neurodegenerative diseases, while the pharmacological modulation of IL-1β is still unsuccessful. Unfortunately, the molecular mechanism underlying neuroinflammation and NLRP3 inflammasome assembly remains elusive. Here we propose that different neuroinflammatory diseases can be linked together in a common disease pathway, of which damaged function should be targeted for therapy. Specifically we propose a new mechanism acting on IL-1β regulation: we hypothesize the existence of a new activity of PML outside tumour environment, acting at the endoplasmic reticulum-mitochondria interfaces (MAMs) as modulator of NLRP3 inflammasome. On these bases, I propose a project in which PML activity at MAMs can be the key link of different neuroinflammatory diseases. Our goals are as follow: 1) to demonstrate that PML post-transcriptionally controls NLRP3 activity at the ER/MAMs compartments and thus IL-1β release via P2X7; 2) to prove that IL-1β release have a strong influence on neuronal environment and survival, and might represent a prognostic factor; 3) to develop new drugs targeting PML/NLRP3/P2X7 axis to overcome the unexpected failure of anti-IL-1 therapies.


**Keywords:** In
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Extended Image Sensing Technologies' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

This project will research new technologies for CMOS image sensors that are needed in the next generation of several application domains.The image sensor research will focus on enhancing the capabilities of current imaging devices:• New design (architectures) and technology (e.g. 3D stacking) for better pixels (lower noise, higher dynamic range, new functionality within the pixel) and more pixels (higher spatial and temporal resolutions) at higher speed, time-of-flight pixels, local (on-chip) image processing, embedded CCD in CMOS TDI pixels.• Extended sensitivity and functionality of the pixels: extension into infrared, filters for hyper-and multi-spectral imaging, better colour filters, programmable filters with LCD cells.Application domains that will be covered are:• Digital Lifestyle: Broadcast, Digital Cinema & Entertainment, Smart home (Grass Valley, Angenieux, Silios, Delft University of Technology, SoftKinetic)• Smart Production (IMEC, C-cam)• High-end Security (Adimec, Angenieux, Le2i, TNO)• Agriculture and food sorting using hyper- and multi-spectral imaging and programmable filters (Silios, Le2i)• Medical healthcare: diagnostics using multi-/hyper-spectral imaging and programmable filters (Adimec, TNO, Silios, Quest and Focal)• Gas detection using multi spectral IR imagers (Sofradir)• Security: gas sensing (Sofradir)The prototype CMOS image sensors for several application domains will be demonstrated together with the sensor related processing.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Nearshore bathymetric inversion from lidars during extreme events' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

The coastal science community currently lacks insights into the rapid morphological evolution of sandy beaches during extreme events. Sediment exchanges occurring between the subaerial and subaqueous regions of the beach are poorly understood, which is explained by the difficulty in measuring the seabed elevation under broken waves with sufficiently high spatial and temporal resolution. The lack of datasets which capture beaches morphological evolution limits the development of accurate numerical models for the morphological evolution of beaches and hence our capacity to predict their long-term evolution. To overcome these challenges, this project will develop lidBathy, a bathymetric inversion tool which uses high-resolution 2D lidar scans of surf zone waves. Lidar scanners have the unique capacity to directly measure both the intertidal beach topography and the sea surface elevation at high spatial (O(cm)) and temporal (O(s)) resolution. Long-range lidar and bathymetric data collected at Narrabeen (Australia) and the Field Research Facility (Duck, N.C.) will be used to validate lidBathy. Lidar data collected at these two sites during past storms will be used to create an unprecedented dataset of beach morphological evolution, in both the subaerial and subaqueous regions, during extreme events. This project will characterize sediment exchanges occurring between the swash and the surf zones by studying the role of surf zone wave properties, water levels, swash statistics and time-varying beach slope. This will provide the first study into the response of the beach system to extreme events at high spatial and temporal resolution at the two most heavily monitored sites worldwide.


**Keywords:** surf zone, non-linear wave dynamics, beach morphological response to storms, c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Flexible hybrid electrical systems for sustainable process intensification on-demand and where required' under Horizon Europe.

assistant: **Concept**

Recognizing the significance of energy efficiency in industry and carbon emissions reduction, FLEXHYON is proposing a clever combination of alternative fully electrified heating systems (microwave, heat pumps, ultrasound) to tackle three specific industrial processes: ultrafast drying of compact material, drying of granular materials and distillation/extraction of ground material to address their urgent need to transition from fossil energy to renewable and low-carbon energy sources.Three optimized prototypes will be built and demonstrated in 3 industrial environments: ceramics, feed production, biomass. The quality and economic impact of the developments will be evaluated using LCA and LCC; environmental and technical performances, health protection, safety will be demonstrated and validated. Sound market strategies will be developed, giving clear indications on scalability, transferability and replicability across different industrial sectors, commercialization and deployment will be achieved through development and validation of set of business models for the 3 business cases.The FLEXHYON solutions will exhibit significantly higher energy efficiency in comparison to traditional fossil fuel-based heating technologies, therefore leading to a reduction in GHG emissions, maximizing primary energy savings, and enabling higher production flexibility (e.g. production on-demand, production on-site). Their scalability (upscaling, downscaling) will allow to better follow market demand and enable leaner production paradigms.To achieve the project goals, FLEXHYON combines 9 partners covering the whole technical value chain required for the development and validation of alternative fully electrified heating systems. The Consortium will also implement different dissemination and c