RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'XR mEdia eCOsystem' (XReco) under Horizon Europe.

assistant: **Objectives**

While media organisations increasingly support non-linear experiences for the consumer, those are still limited to single channels and media domains. Although several media organisations have recently succeeded in breaking data silos, data sharing is mostly limited to the organisation. Thus, there are challenges for producing content feeding multiple channels with different granularities and structures, mainly related to data discovery, management and (re-)use. XRECO will create a new data-driven ecosystem for the media industry, focusing onfacilitating data sharing, search and discovery and supporting creation of news and entertainment content, in particular, the creation and (re-)use of location-related 2D and 3D assets and the creation of XR experiences. The ecosystem core, represented by a Neural Media Repository (NMR), will foster inter-organisation content sharing and provide increased access to content for media creators, considering novel data monetization and rights management policies. A set of AI-based media transformation services are built around the NMR to produce novel media- and XR experiences, including 3D neural reconstructions, neural based device localisation, image stitching, de-/re-lighting and holoportation. The developed technology will be validated in use case scenarios for (i) the news media for XR-based broadcasting and automatic and customized multitarget news publishing, and for (ii) location-based information and entertainment content, with applications in tourism and the automotive industry.


**Keywords:** Data sharing, XR production, content monetization, news production
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Regulating TGF-beta signalling at the transcriptional level and in cancer'.

assistant: **Objectives**

To understand, treat, cure and ultimately prevent cancer we must first be able to understand the basic mechanisms that regulate normal cell growth. One of the cellular factors involved both in normal development and in malignant transformation is transforming growth factor b TGFb. TGFb is a multifunctional cytokine which, in addition to cancer is also implicated in developmental disorders, fibrosis and autoimmune diseases. TGFb signalling has been implicated in both tumour suppression and progression. Although TGFb inhibits inhibits growth of early carcinomas, later in tumourogenesis, it can induce an epithelial-mesenchymal transition (EMT), promoting an invasive, metastatic tumour phenotype. TGFb signals through the activation of Smad proteins. After activation, Smads accumulate in the nucleus where they regulate transcription, either positively or negatively. Although some recent advances have been made, exactly how Smads regulate transcription and how in turn the Smads are regulated during transcription is still remains unclear. The first aim of this application is to investigate which components of the transcriptional machinery get recruited to the active promoters after TGFb stimulation. In order to achieve this an siRNA library screen targeting histone modifying enzymes and chromatin remodelling proteins will be performed.  As mentioned above TGFb has growth inhibitory effects, which are counteracted by Smad7, a negative regulator of the pathway. Although Smad7 has not been identified as an oncogene to date, a genome-wide association screen of tag SNPs performed by our collaborator, has implicated Smad7 as being highly correlated to colorectal cancers. The second aim of this application is to reveal the molecular mechanisms behind this correlation. As colorectal c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Oat CHRomosome Evolution and drivers enabling widespread terminal intergenomic translocations in polyploid species', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Comparative genetic analysis of grasses, one of the most widely distributed plant families and including the three most important human foods, has demonstrated that different groups differ in the evolutionary presence of intergenomic chromosome translocations in polyploid species, including the important crops. The overall goal of our research group is to define the nature and mechanism of terminal intergenomic translocations in oats (Avena) where these are frequent, allowing us to model their contribution to cereal genome evolution. We hypothesize that terminal translocations between oat genomes are related to transposable element activity, a decrease in DNA methylation, and histone modifications that are differential between the genomes. We propose a focused series of complementary molecular cytogenetic, bioinformatic, and epigenetic studies on oat and wheat genomes to characterize this physical genome rearrangement process. A comprehensive model illustrating the potential mechanisms involved in terminal intergenomic translocations will be elucidated by the simultaneous hybridization with the use of genome-specific probes and retrotransposon sequences, and immunostaining of histones and 5-methylcytosine in mitotic cells. The research will reveal why genomes of oats show frequent intergenomic translocations, playing a significant role in their evolution, in contrast to wheats where the translocations are rare. The fundamental research has implications for breeding oats to exploit biodiversity through introgression from wild species, and perhaps enabling additional introgressions in wheat breeding.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Centre europeu de parallelisme de barcelona (cepba) and centre de supercomputatcio de catalunya (cesca)' (ACCESS).

assistant: **Innovation**

Description:CEPBA (European Centre for Parallelism of Barcelona) performs research and development projects based on parallel computing since 1991. CESCA (Centre for Supercomputing of Catalonia) offers services based on the current leading-edge technology and on commercial applications since 1991. Both centres are co-ordinated through the Centre de Computacio i Comunicacions de Catalunya" (C4) to optimise public resources and offer state of the art technology to the research community. Both CESCA and CEPBA were designated Large Scale Facility by the EC back in 1993. The most important aspect of both centres is that they are surrounded by a large University infrastructure with more than 3000 researchers investigating in topics that range from Computational Physics and Chemistry to pure Computer Science or Structural Dynamics. The atmosphere created by those infrastructures influences directly in the relations of local scientists with research institutions at the highest international level.Application to the project can be done by accessing the web page of the facilities www.cesca.es/ang/projects.html. In order to apply, it is necessary to have a contact research team in one of the research institutions in the universitary network in Catalunya. In the case of not having a contact research group, it is necessary to get in touch with Josep L. Larriba-Pey at larri@ac.upc.es who will help you to find such group.Project Manager:Mateo Valero, Centre Europeu de Parallelisme de Barcelona, Centre de Supercomputacio de Catalunya, Jordi Girona, 1-3, Modul D6, Barcelona 008034, SpainTel: +34-93-4016979Fax: +34-93-4017055E-Mail: Mateo@ac.upc.es"
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Development of deuterium metabolic imaging to map body biochemistry with MRI'.

assistant: **Concept**

The global obesity epidemic has resulted in a dramatic rise in metabolic diseases and the development of effective therapies has greatly lagged behind. This could arguably be attributed to a lack of non-invasive (imaging) techniques to characterize disturbances in metabolic pathways. We will investigate the use of dynamic deuterium metabolic imaging (DMI) to dynamically map body biochemistry in humans in 3D imaging mode. DMI relies on deuterium magnetic resonance spectroscopic imaging combined with oral administration of deuterium-labeled compounds.The innovation idea is linked to the MCUBE project of FET-OPEN-01-2016-2017. Here a dual-dipole coil was designed for hydrogen MRI at 7 tesla (300 MHz), which outperformed the state-of-the-art setup of the loop-dipole coil for MRI. The new design is transparent to loop designs, meaning that the setup can be combined with loop coils, which are known to be the optimal setup for low frequency operation. So for DMI, which operates at 45.7 MHz (low frequency) at 7 tesla, an MRI coil array can be designed that not only outperforms MRI, but also enables DMI at uncompromised sensitivity within the same scan session, which will complement the utilization of the MCUBE project.The objectives of the project are: (1) Build and test a body DMI setup for a clinical ultra-high field 7 tesla MRI scanner; (2) demonstrate proof of concept to measure hepatic carbohydrate and lipid metabolism with DMI; and (3) apply DMI in a clinical feasibility study in type 2 diabetes patients. Upon successful completion of the project, DMI will be valorized by the commercial partners and embedded in clinical practice, which opens up a new window for drug studies to directly image their chemical efficacy. Besides its application in metabolic diseases, DMI has p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Characterization of RTEL1 mutations in Hoyeraal-Hreidarsson Syndrome' (RTEL1inHHS).

assistant: **Innovation**

Hoyeraal-Hreidarsson syndrome (HHS) is a multisystem disorder with patients presenting inter-uterine growth retardation, immunodeficiency, and/or aplastic anaemia. Recently, mutations in RTEL1 have been shown to be causal for this disease. RTEL1 prevents genomic instability and maintains integrity of the telomeres by disassembling different secondary structures that arise during DNA replication, repair, and recombination.Although recent discoveries from the host lab and others have shed light on the function of RTEL1 in maintaining genome stability, many outstanding questions remain to be addressed. Currently very little is known about RTEL1 regulation or how it is dynamically recruited to replication forks and telomeres to execute its functions. Moreover, it is not known whether RTEL1 expression or recruitment is regulated by post-translational modifications.  Of the 18 identified mutations, only two have been characterized. As these undefined mutations are causal for HHS and must therefore affect the RTEL1 function, their detailed characterization is likely to shed light on new aspects of its function and/or regulation. The main objective of this project is to characterize the undefined HHS mutations in RTEL1 and determine how they impair the physiological protein function, in vitro and in vivo.To this end, we will take advantage of a complementation system that permits the stable expression of RTEL1 variants in RTEL1 deficient cells, allowing us to study RTEL1 mutant contribution to RTEL1 phenotypes. We will also perform comparative proteomic analysis of the mutants to determine if they abolish specific/novel protein-protein interactions. HHS mutations that present with a defined phenotype or affect a novel interaction will be studied in vivo in a mouse model. In sum
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Developing an Abductive Coding Analysis Toolkit' (DACAT).

assistant: **Innovation**

In qualitative data analysis oriented towards theory-building, many data analysts anchor their methodological approach  explicitly or not  in grounded theory. However, as research in teams develops, handling larger amounts of qualitative data enabled by technological developments, grounded theorys principles are increasingly at odds with current practices; and analysts of qualitative data are left relying on coding procedures that do not match their realities. Following a burgeoning literature and building on the ERC-funded QUALIDEM project, we argue that shifting to an abductive approach of coding, that combines deduction and induction at different stages of data analysis, provides an epistemology to qualitative research that aims at theory-building. This PoC aims to develop abduction as a method of qualitative data analysis by providing a toolkit for abductive coding   the Abductive Coding Analysis Toolkit (ACAToolkit). The ACAToolkit includes three main components: (1) a practical guide ; (2) an educational program for training; (3) an overview of the potentials and limits of existing QDA software - for abductive coding. The toolkit, thereby, targets several audiences: academics, instructors, data analysts and software developers. Our pathway from research to innovation consists of three steps: (1) mapping the existing practices, and tools of abductive coding in different disciplines through a systematic literature review whose results will be presented in a technical report; (2) developing our abductive coding analysis toolkit through research collaborations and consultancy agreements with stakeholders  educators, software developers and data analysts, synthesized during two cocreation workshops; (3) testing the ACAToolkit with different potential end-users during f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'INNOVATIVE GROUND INTERFACE CONCEPTS FOR STRUCTURE PROTECTION'.

assistant: **Objectives**

IINSPIRE aims to foster a new generation of highly qualified researchers and engineers, which will create a critical mass kernel, able to implement a holistic and novel soil-foundation-structure concept for the efficient protection of structures from all ground induced hazards, including earthquakes and all other sources of low-frequency noise and vibration excitations. This concept offers a drastic breakthrough over the existing approaches in crucial aspects:A)Wave inhibition capabilities over broadband low-frequency excitation in all three spatial directions B)General applicability to broad classes of structures and infrastructures C)Simple, reliable and resilient design,  leading to easy and low-cost implementation and maintenanceINSPIRE mainly relies on recent innovative scientific and technological concepts, mainly developed within the broad concept of meta-materials.  The notion of “meta-materials” refers to natural or artificial materials or structures which exhibit extraordinary properties for inhibiting or conditioning wave propagation in all spatial directions over broad frequency bands.  Quite recently, the feasibility of the application of meta-material concepts has been also demonstrated for seismic and infrasound waves. These general developments of metamaterials will be further enriched and advanced through novel absorption and isolation concepts, such as negative effective mass and stiffness


**Keywords:** SEISMIC-PROTECTION NOISE-PROTECTION META-MATERIALS
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Driving the Circular Transformation of the European Automotive Industry with Skills, Digital Tools, and Lighthouse Demonstration' (AutoCE) under Horizon Europe.

assistant: **Objectives**

The European automotive sector faces urgent challenges in achieving life-cycle circularity due to fragmented standards, limited end-of-life integration, skills gaps, and slow adoption of digital tools. AutoCE addresses these barriers through its Circularity Compass Framework, which unites stakeholders, data, and interoperable solutions to accelerate systemic transformation.AutoCE will deliver four core building blocks: the Auto-Circular Sandbox for multi-stakeholder modelling and consensus building; interoperable Digital Product Passports and Digital Twins for lifecycle optimisation; an AI-powered Circular Economy Assistant that provides role-specific guidance, matchmaking, and onboarding; and an Integrated Circularity & Sustainability Monitor to track environmental, economic, and social performance. These innovations will be validated in a Lighthouse Recycling Factory, producing an investment-ready blueprint for advanced disassembly, remanufacturing, and material recovery.Aligned with initiatives such as Catena-X and contributing to CEN/CENELEC pre-standards, AutoCE ensures interoperability, SME accessibility, and policy relevance. Co-creation workshops, training, and policy briefs will build stakeholder capacity and foster inclusivity.By delivering harmonised tools and frameworks, AutoCE directly supports the call’s expected outcomes: a shared understanding of circularity, improved resource sovereignty, adoption of DPPs and Digital Twins, harmonised ecosystem requirements, and a roadmap for visible industrial lighthouses. In doing so, AutoCE strengthens Europe’s competitiveness, reduces reliance on virgin resources, advances climate neutrality, and ensures a just and inclusive transition for workers and SMEs.


**Keywords:** Circular Economy, Automotive Industry, Digi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Hydrodynamics effects on seagrass morphometry and allometry, and feedback mechanisms'.

assistant: **Concept**

The effects of currents on seagrass morphometry and allometry and the resultant growth and biomass distribution will be studied by long term exposure in flume tanks. Seagrass responses to resist hydrodynamic disturbances and their feedback effect on local hydrodynamics will be quantify.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Advanced cobalt based catalyst for fischer-tropsch synthesis' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Objectives The aim of the programme is the development of an advanced catalyst presenting a higher activity for paraffins synthesis from syngas and used in a new generation of slurry Fischer-Tropsch process utilizing natural gas as feedstock. The partners will master the deposition of the promoters, allowing to increase the activity of cobalt based catalysts, through original manufacturing techniques, and evaluate the catalyst performances in slurry reactors. Furthermore, some characterization techniques will be adapted to the in-situ characterization of the best catalytic formulations. The association of the in-situ techniques with kinetic measurements will also provide an advanced understanding of the reaction mechanism and the catalyst reconstruction under syngas. Technical Approach A first phase will consist in the standardization and/or calibration of characterization methods and test equipments which are intended to be used by the partners. The second phase will be devoted to the design and screening of new active phases. In parallel, kinetic studies and in-situ characterization of the catalysts will be performed to understand how catalysts operate and evolve under reaction conditions. The third phase will be devoted to the final development at lab-scale of the best catalytic formulation including the support and its adaptation to slurry phase operation. The fourth phase will allow to synthesize the results obtained during the previous phases through the achievement of a technical file for development studies. A fifth phase devoted to the management, intermediate and final reporting, simultaneously to the other phases. A first economic study will be performed using catalytic performances obtained at the end of phase 2 (mid term assessment), and a second one near t