RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Off line internet-enabled tools for information sharing between researchers in the south and the north.' (1998-2002) under Fifth Framework.

assistant: **Objectives**

The objective of this measure is to increase the involvement of scientists in Developing Countries in the Community Programmes in order to contribute to the optimal use of research possibilities and research results both in the North and in the South, especially focused on international partnerships. More specifically, it will contribute to the optimal use of Internet tools adapted to the special settings of Developing countries where we will have to deal with slow and unreliable connections for the years to come. The off line tools developed under this measure will enable developing country Focal Points to participate more intensively in the SHARED system (www.shared.de) and similar systems based on the driving IKON technology through: The development of off-line tools for data management, the development of training materials and specific manuals and the training of Focal Point Managers.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Structural and biophysical mechanism of microRNA nuclear export'.

assistant: **Objectives**

MicroRNAs are a recently discovered class of small non-coding RNAs that act as post-transcriptional regulators of gene expression by silencing target mRNAs. They have wide ranging roles in many cellular processes including cellular proliferation, stress response, apoptosis, development and differentiation. Altered expression of microRNA has been implicated in tumorigenesis, and microRNAs are recognised as modulating factors in numerous cancers including gastric cancer, lung cancer and lymphocytic leukaemia. Specifically, microRNA functions within the cytoplasm in concert with the human-induced silencing complex by binding the 3’ untranslated region of the target mRNA. This binding to target mRNA effectively inhibits expression of the protein, and thus mediates the gene silencing effect of microRNA. This project aims to elucidate the structure and biophysical basis of the nuclear export complex formed by pre-microRNA (precursor of microRNA), RanGTP and exportin-5. These goals will be achieved using a combination of structural, biochemical and biophysical approaches. X-ray crystallography and nuclear magnetic resonance will be utilised to study the structure of the export complex of microRNA. In parallel with the determination of the complex structure, the key residues involved in complex formation will be identified by mutagenesis, cross-linking and further NMR approaches. Furthermore, a range of biophysical techniques will be employed to study the thermodynamic and kinetic basis for the formation of the microRNA export complex. The information provided by this study will be of the highest international standard and will open novel avenues to therapeutic design as well as represent a significant advance in our understanding of cellular biology. Importantly, it will provi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Development of genetically engineered highly competent insulin-secreting cell lines' (1994-1998) under Fourth Framework.

assistant: **Objectives**

The objectives of the project are to: 1. develop highly competent insulin-secreting cell lines by genetic engineering. Such cells should respond to glucose as promptly and consistently as normal pancreatic beta-cells and should have high insulin content. 2. develop and optimise methods for micro-encapsulation of the engineered cells for protecting against immune damage; characterise conditions for growth and survival of beta-cells in the microcapsules.3. characterise mechanisms of signalling that mediates secretion in the native and the engineered cells before and after micro-encapsulation 4. transplant diabetic animals with highly competent insulin-secreting cells encapsulated in immune barrier and study the effects of such procedures on diabetic status and on the transplanted cells. A hallmark of the approach would be to manipulate GLP-l- and CAMPmediated signalling pathways to increase competence of beta-cells. Background works from the coordinator's laboratory establish critical role of CAMP system and the incretin hormone GLP-l in regulating stimulus-secretion coupling in pancreatic beta cells. Several of the currently available beta cell lines do respond to physiological range of glucose concentration but not as promptly and as consistently as does the normal beta cells. In the proposed project we shall engineer cells to stably express proglucagon which would be processed to GLP-l within the beta-cells and the engineered cells would secrete insulin and GLP-l. The latter would make beta cells competent by an autocrine interaction as well as provide GLP-l for other physiological functions. Variations of the approach namely expression of a constitutively active mutant of stimulatory subunit of G protein and a constitutively active mutant of GLP-l receptor will be pur
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Milos Geothermal Energy Driving ORC Turbo generator and Seawater Desalination Plant'.

assistant: **Concept**

The main objective of this innovative demonstration project is to provide the Milos community with sufficient quantity of clear drinking water in a cost and energy efficient way avoiding environmental impacts. This objective will be achieved by combining the technologies of ORC electricity generation, ME distillation and absorption chilling. Technological knowledge generated during the project realisation will be available on European level and this is essential to addressing the serious issues of sustainable development. The project will contribute to sustainable development by focusing on the local community's key problem crucial for social weel-being and economic competitiveness. The project leads to an improvement of the local economy, life quality, emission reduction.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'AUTOMATED DIAGNOSTICS AND RADIOLOGICAL READING FROM LUMBAR SPINE MRI', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

CoLumbo is an innovative AI online platform for diagnosing herniated disc and other spinal pathologies, capable of MRI reading, and medical history analysis. The innovation is based on fully convolutional neural networks (FCNN) for MRI reading, and uses a specially designed patent pending algorithm to compensate for a smaller number of training datasets without loss of accuracy or reliability.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Bridging the gap between public opinion and European leadership: Engaging a dialogue on the future path of Europe.' (EUENGAGE).

assistant: **Innovation**

The goal of the EUENGAGE Project is twofold: first, to inquire into the current tensions between supranational EU governance and popular mobilisation at the national level, critically questioning EU-driven policies and EU legitimacy; and second, to propose remedial actions based on sound empirical research on the relationship between public opinion, national and supranational political elites. The medium to long-term evolutionary trend of the EU system of supranational governance has already in the past given rise to a manifestation of problems. It has become clear that the pace of integration proposed from the top, and some side-effects of integration—austerity, transnational redistribution, economic insecurity, immigration—are difficult to accept for large parts of Europe’s citizens. This misalignment is obviously a crucial issue for any system of governance that aims - as the European Union has repeatedly affirmed - to be inspired by democratic principles. The EUENGAGE project takes seriously the present state of affairs and identifies in the conflicting messages emanating from the functioning of political representation a critical and urgent problem for the future of the EU. The EUENGAGE proposes to set up an interactive, dynamic, multilevel and replicable quasi-experimental research design. Using a variety of instruments and techniques, this design will allow us not only to study the process of representation in vivo, but also to test experimentally how innovative and efficient interactions between citizens and politicians can increase citizens’ awareness of the common problems of the Union, and the ability of the European leadership to respond innovatively to the discontent of public opinion.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Parametrization in the control of dynamic systems'.

assistant: **Innovation**

The goal of the project is to increase and deepen the knowledge on the control of dynamic systems at the Department of Mathematics and Statistics, University of Kuopio, based on the idea of flatness, developed recently by M. Fliess and co-workers in France , and on the methodology called parametrization. Here dynamic systems has a control-theoretic meaning of being controlled ordinary or partial differential equation (PDE) systems (of parabolic evolution type). A technically feasible and computational test f or checking flatness and parametrizability is still missing. Furthermore, extensions to nonlinear partial differential systems still waits for a developer. Linear partial differential systems can already be controlled via a flatness-based technique, a so-c alled parametrization method. The scientific objective is to further develop, together with advanced European specialists, control methodology of dynamic systems via flatness and parametrization concepts, and try to extend these results to nonlinear PDE sy stems. Some methodological results developed earlier in our department will also be developed further and applied. A central application field is control of quantum mechanically described systems. This application field has a key role in developing new mea surement principles and corresponding technologies,and interface electronics for future, e.g. mobile, communication systems relying on quantum mechanical principles in quantum computation and quantum control. Due to the plans to develop a new Master of Sci ence curriculum in engineering in the University of Kuopio, and due to the etablation of new research and development units of multinational high-tech companies, e.g. Honeywell and Nokia, in Kuopio and Northern Savo region, knowledge of advanced control e ng
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Design of optimised systems for monitoring of radiation and radioactivity in case of a nuclear or radiological emergency in Europe'.

assistant: **Innovation**

The Call for this project proposal describes the objective as “to develop a methodology for optimising the design of monitoring systems for timely and effective decision making in an emergency”. This objective together with the expected impact (“A tool for making more efficient use of monitoring resources and improving the bases for decision making in emergencies, in particular in the context of the need to upgrade/replace during the next decade many of the monitoring systems installed post-Chernobyl”) can be seen so that the project shall provide all relevant information needed in design of monitoring strategies and show how this information can be used in planning of monitoring systems in an optimised way.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Researchers Night in Macedonia'.

assistant: **Innovation**

Friday 26 September 2008 has been declared Researchers’ Night by the European Commission. Across Europe, hundreds of activities will be showing how exciting, fun and relevant to day-to-day living research actually is. The target group for the events is the widest public possible, especially young people. Activities will include experiments, workshops, hands-on activities, science shows, exhibitions, presentations, photos competition and many other opportunities to meet researchers face-to-face.  Main idea is this year for the first time in Republic of Macedonia to organise researchers’ night targeting same objectives esteemed across Europe. It will be excellent opportunity for widest public to learn about the importance of sciences to our lives and our future. The main objective of this project is to create and develop positive links between research community and wider population.   Primary goal is to involve as much as possible larger spectators of the event and their introduction with the profession Researcher in Macedonian society.   The National Agency for European Educational Programmes and Mobility as a Bridgehead organization for ERA-MORE will use this opportunity to broaden its visibility for European Research Area, actively promote and establish new prospects.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Quality and identification standards for biofungicides' (1994-1998) under Fourth Framework.

assistant: **Objectives**

The project targets Area 2.1.4 in the Standards and Measurements program, and aims to: - develop data which can be used for the formulation of European standards; - definition of additional quality criteria for biofungicides especially Trichoderma products; - development of identification techniques, e.g. molecular fingerprinting methods for biofungicides, as fungicidal and human safety qualities vary considerably within a strain of an organism; - develop rapid easy to use test kits for field use and possibly by the registration authorities. These kits could be utilized for checking contamination and to confirm that it is the registered isolate(s) which is in the fungicide; - the establishment of a biofungicide culture collection where the active organisms, and possibly some common contaminants are deposited to be used as reference material for the test kits mentioned above; - establishing how activity of the product should be defined; - standardize efficacy tests for biofungicides. Strict quality requirements are requested by responsible biofungicide manufacturers, and needed both to guarantee the function of the product and to exclude the risk for human infections or allergic reactions. A failure in any of these respects could jeopardize the whole movement toward environment friendly biopesticides.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how '5G Intelligent Automotive Network Applications' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

5G-IANA aims at providing an open 5G experimentation platform, on top of which third party experimenters (i.e., SMEs) in the Automotive-related 5G-PPP vertical will have the opportunity to develop, deploy and test their services. An Automotive Open Experimental Platform (AOEP) will be specified, as the whole set of hardware and software resources that provides the compute and communication/transport infrastructure as well as the management and orchestration components, coupled with an enhanced NetApp Toolkit tailored to the Automotive sector. 5G-IANA will expose to experimenters secured and standardized APIs for facilitating all the different steps towards the production stage of a new service. 5G-IANA will target different virtualization technologies integrating different MANO frameworks for enabling the deployment of the end-to-end network services across different domains (vehicles, road infrastructure, MEC nodes and cloud resources). 5G-IANA NetApp toolkit will be linked with a new Automotive VNFs Repository including an extended list of ready to use open accessible Automotive-related VNFs and NetApp templates, that will form a repository for SMEs to use and develop new applications. Finally, 5G-IANA will develop a distributed AI/ML (DML) framework, that will provide functionalities for simplified management and orchestration of collections of AI/ML service components and will allow ML-based applications to penetrate the Automotive world, due to its inherent privacy preserving nature. 5G-IANA will be demonstrated through 7 Automotive-related use cases in 2 5G SA testbeds. Moving beyond technological challenges, and exploiting input from the demonstration activities, 5G-IANA will perform a multi-stakeholder cost-benefit analysis that will identify and validate market
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Graphene Flagship 2D Experimental Pilot Line' under Horizon 2020.

assistant: **Concept**

The 2D Experimental Pilot Line (2D-EPL) project will establish a European ecosystem for prototype production of Graphene and Related Materials (GRM) based electronics, photonics and sensors. The project will cover the whole value chain including tool manufacturers, chemical and material providers and pilot lines to offer prototyping services to companies, research centers and academics. The 2D-EPL targets to the adoption of GRM integration by commercial semiconductor foundries and integrated device manufacturers through technology transfer and licensing.The project is built on two pillars. In Pillar 1, the 2D-EPL will offer prototyping services for 150 and 200 mm wafers, based on the current state of the art graphene device manufacturing and integration techniques. This will ensure external users and customers are served by the 2D-EPL early in the project and guarantees the inclusion of their input in the development of the final processes by providing the specifications on required device layouts, materials and device performances. In Pillar 2, the consortium will develop a fully automated process flow on 200 and 300 mm wafers, including the growth and vacuum transfer of single crystalline graphene and TMDCs. The knowledge gained in Pillar 2 will be transferred to Pillar 1 to continuously improve the baseline process provided by the 2D-EPL.To ensure sustainability of the 2D-EPL service after the project duration, integration with EUROPRACTICE consortium will be prepared. It provides for the European actors a platform to develop smart integrated systems, from advanced prototype design to small volume production. In addition, for the efficiency of the industrial exploitation, an Industrial Advisory Board consisting mainly of leading European semiconductor manufacturers a