RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Regulation of ensothelial barrier properties through activation of Rho family GTPases' (2002-2006) targeting Sixth Framework.

assistant: **Abstract**

Endothelium is a dynamic orhan with secretory and immunological functions that plays a key role in homeostasis, thrombosis and inflammation. Endothelial cells create a continuous monolayer lining blood vessels, semi-permeable to macromolecules, salutes and liquid, highly regulated by blood-born mediators.The endothelial barrier function is critically dependent on the integrity of cell-cell adhesion structures, especially the tight junctions and the adherens junctions (AJ). Endothelial AJ associates with acti n cytoskeleton and link neighbouring cells through the transmembrane VE-cadherin (Vascular Endothelial cadherin), the molecule that constitutes the backbone of AJ. Studies have shown that disassembly of AJ is an essential feature of the increased endothelial permeability response.Endothelial AJ are dynamic structures which respond to inflammatory mediators and thus modify their adhesion strength and alter endothelial barrier function. Cell-cell adhesion strength is regulated by: a) the extracellular cadherin repeats domain, and b) the cadherin cytoplasmic domain where p120- and b-catenins bind.These molecules function as essential linkers between cadherin and the actin cytoskeleton, which is requirement for strong cell-cell adhesion. Proinflammatory mediators such as thrombin, histamine and bradykinin activate their endothelial surface receptors and induce increased endothelial permeability responses through second messengers activation. In such cases endothelial cell-cell adhesion mediated by AJ is modulate d from strong to weak.The proposed studies aim to explore mechanisms responsible for reversal of the permeability increase and barrier recovery. We will study how endothelial adhesive structures and the associated cytoskeleton regulate barrier function. Specific
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Multidisciplinary approach to study effects of beneficial rhizobacteria on induced plant defences to abovegroung herbivorous insects'.

assistant: **Objectives**

Plants are members of complex communities and they interact with other plants, insects and microbes. These interactions have a high economic impact in agriculture, like is the case of pests and pathogens attacking a certain crop. Traditionally such interactions have been study one-by-one, but recently a high number of investigations are focused in the study of the relationships in a wider context. In the context of Integrated Pest Management, the use of strategies that induce plant resistance is a very promising strategy since it can be more effective than the use of pesticides in some cases The use of rhizobacteria is one method to induce systemic resistance in plants, as well as to promote plant growth. Induced defences comprise direct defences such as secondary metabolites and protease inhibitors that negatively affect herbivore growth and survival. And they also comprise indirect defences such as herbivore-induced plant volatiles and herbivore-induced extrafloral nectar that enhance the effectiveness of natural enemies of herbivores, such as parasitoids or predators. These mechanisms are providing plants two ways of defence against insect pests, and in the context of integrated pest management where natural enemies are frequently released, they can be very effective for pest control. It is essential to understand the mechanisms that are involved in these interactions in order to apply this strategy to the different plant-insect interactions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Diagnostics and control of rodent-borne viral zoonoses in europe' (1998-2002).

assistant: **Concept**

We focus on rodent-borne viral zoonoses in Europe with emphasis on hantaviruses. Rodents are the reservoir of hanta-, arena- and cowpox viruses, and may also be that for Borna disease virus. Close and long-term interaction between virologists and zoologists is a prerequisite for our successful research. In Europe, the hantaviruses Puumala, Dobrava and Saaremaa cause hemorrhagic fever with renal syndrome. We aim to learn more about the epidemiology of viral zoonoses in rodents, transmission to humans, and human epidemiology in Europe. Large-scale epidemiological studies may define long-term consequences of hantavirus infections. Rapid bed-side" diagnostic tests will be developed. Reverse genetics, new animal models, characterization of humoral and CTL response, HLA haplotypes, other host genetic factors, and cell biology of virus infection will be studied to understand the pathogenesis and to develop antivirals."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'VIsual representations of VIew Relations to support effective data analysis on large and high-resolution displays' in the context of a Horizon 2020 call.

assistant: **Objectives**

In VIVIR, I will conduct state-of-the-art research on supporting collaborative face-to-face data analysis. This is motivated by the increasing need for interdisciplinary teams to collaborate on understanding and analysing data. Additionally, as the scale and complexity of data increase, so does the demand for data-based insights and decision-making. My approach is to empower people who are working with large and complex data, by letting them lay out as many visualization views (in the following, denoted views) as necessary on large displays, and creating specialized meta-visualizations to show relations between these views. These meta-visualizations will allow team workers to be aware of each other’s work and the changing view- and data-relationships as they work. While the potential of view meta-visualizations has been acknowledged , there are currently only a few frequently used and considered essential examples of such meta-visualizations. These might show that data in two views are compared in a third view, or that a view shows a subset of the data shown in another view. Most importantly, there has been no thorough exploration into the power and potential of meta-visualization support for data-driven decision-making. To understand the potential impact of meta-visualizations on data analysis, we need to take a structured approach, to formalize these possibilities, which will improve our abilities to support knowledge worker teams as they face the challenges of analyzing increasingly complex data.In brief, data can be difficult to understand. Creating visualizations of data lets people see their data more clearly. As data size and complexity increases, more views are needed to reveal the information hidden in data. Large displays might be useful to solve this. However
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Prospective Analysis for the Mediterranean Region' (MEDPRO), addressing dissemination and exploitation.

assistant: **Impact**

In response to SSH-2009 – 7.1.2, the MEDPRO project will undertake a deep foresight analysis of the development issues in eleven countries in the Southern and Eastern Mediterranean participating in the Barcelona process and in the Union for the Mediterranean. The project will undertake an analysis of the current state and prospective development in main areas of socio-economic development: Geopolitics and governance; demography, ageing, migration, health and gender issues; sustainable development, management of resources, adaptation to global warming; energy and climate change mitigation; economic development, trade and investment; financial services and capital markets and human capital, education and development of skills. It will then bring the partial foresight analyses in these areas into a broader framework of quantitative general equilibrium modelling, and be completed with qualitative scenarios for regional and broader integration within the region and with the EU and policy conclusions for the EU approach. Given the broad scope of the research to be undertaken, the consortium has been composed with the aim of ensuring three equally important qualities: scientific excellence, multidisciplinary structure and deep insight into Mediterranean affairs. The coordinating institute is therefore collaborating closely with three other institutes with deep insight in Mediterranean affairs and European Neighbourhood Policy. Whereas the main objective is to provide targeted scientific support to the future development of the relations between the EU and the Mediterranean region, the impact of this project will be underpinned by an exceptional effort of dissemination in both the EU and the Southern and Eastern Mediterranean countries.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Spin-Selection using Chirality: A Supramolecular Approach'.

assistant: **Concept**

Organic electronics which exploits charges (electrons or holes) of π-conjugated molecules/polymers has garnered attention in the past decade due to the low cost, ease of processability and most importantly the flexibility to tune the electronic properties through chemical synthesis. In addition to charge, spin as a quantum number provides exciting opportunities to store data in memory devices, in spin filters and spin-based organic light-emitting diodes. Typically in spintronic devices, switching of the magnetism of one of the ferromagnetic layers is required to attain spin-selectivity. Recent works have demonstrated high (>60%) spin-selectivity in organized chiral double-stranded deoxyribonucleic acid (DNA) without the use of magnetic materials. The high spin-selectivity was attributed to the creation of chiral field in which the electron-transport takes place through DNAs. It is to be noted that the organization of DNA strands is pivotal in achieving high spin-selectivity. Presently, the main focus is on bio-inspired molecules such as peptides and DNAs. Due to the versatility and processability of organic semiconductors, they are ideal candidates for obtaining chiral electron flow leading to functional organic spintronic devices without ferromagnets. Thus the present proposal aims at design, synthesis and characterization of chiral π-conjugated oligomers and polymers with ordered supramolecular organization on surfaces as testbeds for spin-selective electron transport. Chiral fluorene oligomers/polymers are known to form cholesteric liquid crystal phases on surfaces. Based on this, our design includes chiral fluorene based oligomers and polymers attached with pendant acid groups to anchor on surfaces to obtain chiral supramolecular organization desired for the electro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Advancing Semiconductor Reliability with Device Aware Testing for Next-Generation Non-Volatile Memory Technologies'.

assistant: **Concept**

Non-volatile memory (NVM) technologies are essential to modern society, supporting key functions in healthcare, automotive safety, and communication infrastructure. These cases highlight the importance of NVM reliability and the need for rigorous testing of memory semiconductors to protect technologies that impact millions of lives.Advanced memory technologies come with unique physical properties and new failure modes, making traditional testing methods less effective. This can lead to test escapes—defective chips passing undetected—posing risks to critical applications. It also lowers yields (the percentage of defect-free chips) and raises operational costs.Our solution, the Device Aware Testing (DAT) platform, integrates precise physical defect modeling into the testing process. This improves fault detection accuracy by two orders of magnitude, reducing the likelihood of defective chips reaching the market and improving product reliability.The POPCORN project will develop and demonstrate a prototype of the DAT platform in real-world settings, advancing it to Technology Readiness Level (TRL) 6. Key activities include building a scalable defect and model library, automating fault modeling, and test generation, and demonstrating the platform in an industrial setting.By the project’s end, we expect societal and economic benefits, including improved semiconductor quality, increased reliability of critical technologies, and a boost in Europe’s semiconductor industry. With interest from major players in the industry, the project is on track to launch its market-ready product by 2031, offered via a Software as a Service (SaaS) model for sustainable profitability.


**Keywords:** Device Aware Testing, Non-Volatile Memory, Semiconductor Reliability, Fault Detection, Emerging Me
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Methodology for Statistical Analyses, Modelling and Data Collection', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The specific objectives of this project are to produce key modelling elements for forecasting passengers and freight within a suitable modelling framework, in such a way that it can be extended subsequently into a European Transport Model Methodology for forecasting traffic and congestion on the Trans European Networks.The research will define the data collection methodologies required for the collection of specific types of data and will develop analytical methodologies needed to interpret the data. The project will:- develop an overall modelling framework within which various levels of data can be manipulated to solve specific problems;- develop a typology of methodologies for building origin destination matrices of passengers and test two of these methodologies by means of case studies;- develop a methodology for collecting data on freight flows directly from the computer systems owned by transport operators / shippers;- develop a methodology for building origin-destination matrices of freight from a survey of shippers and undertake a case study. %Germany, Holland, France, United Kingdom.A first O-D passenger transport matrix in covering the entire EU15 at NUTS-2 level %Links with other Strategic Research projects: INFOSTAT, MESUDEMO, MEST, OD-ESTIM, STEMM
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Dissecting the role of sex hormones in human antiviral immunity' in the context of a Horizon 2020 call.

assistant: **Objectives**

COVID-19 severity and mortality are consistently higher in men than women. Still, the mechanisms that underlie sex differences in human antiviral immunity remain poorly understood. Therefore, investigating sex-specific regulation of immune responses is a critical step for developing novel and effective antiviral therapies. The overarching goal of SHIFT is to dissect the precise contribution of sex hormones to human antiviral immune function by studying the immune system of individuals as they undergo sex-reassignment therapy with sex hormones. The three specific aims proposed are 1) to evaluate the sex hormone contribution to viral infection susceptibility, 2) to characterize sex hormone effects on the immune-microbe interactions and balance, and 3) to assess sex hormone effects in antiviral immune responses during infection. SHIFT will combine the experienced researcher’s advanced knowledge in sex hormone regulation of immune function and metabolism, with the host lab’s state-of-the-art multi-omics technologies, advanced expertise in systems immunology analysis and established collaborations in Sweden. Aims will be achieved during a planned 24-month training at Karolinska Institutet that involve technical training (sample collection and processing), analytical training (integrative computational analysis and statistics), and development of transferrable skills (project management, mentoring, leadership and communication). The two-way transfer of knowledge in SHIFT will lead to implementation of new techniques, mentoring of trainees, and identification of sex-hormone regulated pathways in antiviral immunity that will be valuable for vaccine design, antiviral therapies and immunomodulatory therapies at large. Further, the MSCA fellowship will provide a strong training pa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Financing health care in nis and ceec' s not in the pre-accession phase' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

In the past the countries of Cheek's and NIS all experienced major economic shocks. The health care sector also suffered from earlier policies. The official ministerial declarations on health reform contain goals such as improving the population's health, improving the system' s efficiency, cost containment, better use of resources, increased quality of services, access and equity. The capacity for health reforms is weak and due to the leadership instability, the change process is often poorly managed. The project will establish a network of centres of expertise across the region by integrating scientists from NIS and Cheek's not in the pre-Accessing Phase in the network of European centres in the area of health systems research. The project will provide systematically prepared information about financing of health care systems, a comparison and benchmarking of the actual health financing systems in the countries concerned.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Support for SMEs collaborative aeronautical technical research-Integrated Projects'.

assistant: **Objectives**

Aerospace industries have provoked important developments in Europe's infrastructure. They have contributed massively to the economies of Europe and the wealth of a number of its regions; they employ a huge workforce (more than 1 million jobs depend direc tly or indirectly) and, through exports, contribute strongly to Europe's ability to develop the quality of life of its citizens. Aerospace SMEs have been working for long in the shadow of large industrialists. Some are now leading European RTD (Research a nd Technical Development) projects fitting with SMEs needs, capabilities and expected time to product. In the Framework Programme (FP6), the Commission aims to allocated 15% of the total financial resources assigned to Integrating Research thematic progra ms to SMEs. SMEs awareness has considerably increased, expressed needs from SMEs are actual, and nevertheless a large amount of work remains to be accomplished in order to help SMEs in creation of effective consortia and in preparation of successful servic ed SME Integrated Projects proposals. SCRATCH-IP Partners objective is to improve the present situation by means of direct contacts with efficient SMEs, already visited by the SCRATCH consortium, and help to carry ideas into serviced SME IPs/STREPs propos als. Four of the most efficient SCRATCH partners from F, UK, D and B having expertise in European Research and SMEs in the field of Aeronautics bring their know-how and capabilities in SCRATCH-IP which final goal is to service and submit two SMEs led Large STREPs in the field of Aerospace Programme for the final aeronautical calls for proposals in FP6. The four mentioned Partners will work in agreement with the other Partners of the SCRATCH endeavour: NL, I, E, IL, EL, P, RO, PL, HU, S, IRL and CZ; they ar e linke