RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Modelling undiagnosed muscular dystrophies using patients's stem cells'.

assistant: **Innovation**

Neuromuscular Diseases (NMDs), affecting both children and adults with a prevalence of 1 in a 1000 people, form a large and heterogeneous group of genetic diseases causing progressive degeneration of skeletal muscles. Most NMDs result in chronic long-term disability imposing a significant burden on patients, families and public health care. In many cases, patients die prematurely from respiratory, and in some cases cardiac, muscle impairment. There are more than 200 NMDs, including over 30 types of Muscular Dystrophy (MD) which results from the mutation of genes controlling muscle functions and structures. The classification of MDs is not fixed but evolves with the constant discovery of new genes/mutations responsible for these diseases. Despite more than 40 genes involved in MDs have already been identified many genes are still to be discovered. In Europe, thousand patients with MD are currently without molecular diagnosis. Delayed or inaccurate diagnoses postpone the adequate care and may have irreversible consequences for the patients. MUMDUPSC aims combining descriptive clinical diagnosis, genomics and disease modelling from patients’ induced Pluripotent Stem Cells (hiPSC) to identify both molecular mechanisms and genetic mutations underlying undiagnosed muscular dystrophies (UMDs). Specifically, I propose to generate hiPSC from selected UMD patients and investigate their transcription profile during skeletal muscle differentiation compared to control cells (unaffected or affected with known MDs). By identifying, for the first time, DEGs specifically modulated in UMDs, MUMDUPSC will reveal the genes and pathways specifically contributing to the diseases. It will represent a proof of concept for the classification of unlabeled muscle pathologies and, in the long term
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Assessing and improving the innovation management capacity of Walloon SMEs through specialized EEN services' (KAMWAL).

assistant: **Innovation**

The KAMWAL project aims to set up and to validate through some real-life cases two new kinds of advanced services for SMEs in the Walloon region of Belgium with the support and in the framework of the Enterprise Europe Network Wallonia consortium.These services are the KAM service, in the framework of the H2020 SME Instrument, in order to provide Walloon beneficiaries with dedicated and specialized coaching and the IMC service aiming to improve the Innovation Management Capacities in SMEs with high growth and international potential.The project is expected to cover the end of 2014 starting from dedicated trainings related to the IMP³ROVE tool which will be used by the EEN staff in charge.This EEN staff in charge will be composed of 2 experienced innovation consultants already member of the EEN Wallonia team.In the framework of the action, it is shown that the duration and the available means allow to work on a set of maximum 10 Walloon cases either with the KAM service or with the IMC service.


**Keywords:** Entreprise Europe Network, Wallonia, innovation, support , SME
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Intelligent Monitoring System based on Acoustic Emissions Sensing for Plant Condition Monitoring and Preventative Maintenance' (MOSYCOUSIS).

assistant: **Concept**

Unexpected failure in an industrial production chain does not only involve the costs of failed parts replacement and the associated man-hour labour, but downtime costs have also have to be considered. To keep a machine functioning well it is a must to have good predictive maintenance, as it helps to reduce operating risk, avoids plant failures, provides reliable equipment, reduces operating costs, eliminates defects in operating plant and maximises production. Acoustic Emission (AE) is a phenomenon of transient elastic wave generation in materials under stress. When the material is subjected to stress at a certain level, a rapid release of strain energy takes place in the form of elastic wave which can be detected by transducers placed on it. Plastic deformation and growth of cracks are among the main sources of AE in metals. Though AE can came form any system under movement, the main source is doubtlessly from rotating machinery. Sources of AE in rotating machinery include impacting, cyclic fatigue cracks, friction, turbulence, material loss, cavitation, leakage, etc. In most cases the SMEs machine owner would be satisfied with a simple affordable device that is able to warn them from critical equipment failure.Recent developments in sensing technology, microprocessors, and miniaturised radio transceivers has enabled a new generation of Wireless Sensors Networks. The future of these sensors is to have an ubiquitous sensing nodes that will autonomously report on operating conditions, and that this data will be used to facilitate structural health monitoring, embedded test & evaluation, and condition based maintenance of critical industrial rotating machinery without the use of expensive cabling. In addition, in order to provide sensing networks which are truly autonomou
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Mathematical Theory of Kinetic Equations and Applications toCoagulation and Fragmentation processes' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The work we propose focuses on the rigorous mathematical development of kinetic theory and the applications of its techniques to the study of models of population dynamics and cell fragmentation and growth in biology, to the dynamics of coagulation and fragmentation processes in physics, and to more recently developed models in the field of collective behavior. The aim is then twofold: to advance the understanding of basic equations in kinetic theory, such as the Boltzmann equation, and to employ known or newly developed techniques in this field to the rigorous treatment of models in the above mentioned areas, such as the Becker-Döring equation for nucleation, the growth-fragmentation model for cell populations, or individual-based models for collective behavior.The proposed work on the Boltzmann equation is a continuation of previous works of the applicant in collaboration with M. Bisi, B. Lods and C. Mouhot, mainly based on perturbation and entropy techniques in the study of asymptotic behavior of the elastic or inelastic Boltzmann equation.The work on applications builds on recent advances showing the successful applicability of techniques form kinetic theory in some models involving coagulation and fragmentation. In particular, we expect to obtain improved results on the asymptotic behavior of the growth-fragmentation equation, including the development and analysis of computer code to calculate the asymptotic profile; to apply entropy techniques to the full coagulation-fragmentation equation in order to study its speed of convergence to equilibrium; and to be able to apply perturbation techniques in the study of the scaling hypothesis for coagulation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Gene expression during repair of Salmonella enterica serovar Typhimurium after exposure to cold atmospheric gas plasma: a transciptomic analysis using a DNA microarray approach' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The demand for fresh or minimally processed food has grown rapidly in recent years. For this reason non-thermal processes have gained importance as a potential technology to replace the current thermal processing of food which results in extensive undesirable changes in quality attributes. An emerging technology is the use of nonthermal ionized gases also known as cold gas plasmas. The low operating temperatures of cold atmospheric plasmas makes them well suited for treating surfaces of foods contaminated with microorganisms. Although the use of cold atmospheric plasmas for microbial inactivation has been studied since the mid-1990s, the application of this technology to low-temperature food decontamination is much more recent. Although there are some studies on the effects of using nonthermal plasma in food processing, there has been no research performed with the objective of understanding the requirements of bacteria during the resuscitation of sublethal injury following exposure to gas plasma. The first aim of this project is to investigate the effect of cold atmospheric gas plasma on the inactivation of Salmonella enterica serovar Typhimurium by the collection of kinetic data during inactivation on abiotic surfaces, (such as packaging film) and biotic surfaces (such as vegetable tissues). A further aim is the measurement of the up-regulation of genes during resuscitation from damage inflicted by gas plasma. This will use a transcriptomic approach and a DNA microarray to identify time-dependent changes in the gene expression. In this way, we will focus on the important cellular events during the resuscitation of sublethally injured Salmonella Typhimurium cells. This will allow an understanding of the regulatory mechanisms involved during the resuscitation of subleth
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'A next generation diagnostic device that effectively screens for breast cancer in all tissue types, without the use of ionising radiation', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Tiro Medical was formed in 2014 by a multidisciplinary shareholder group, including academic and healthcare organisations along with clinical and industry experts. Tiro Medical develops tools for the Digital Medicine sector, creating products that enhance the diagnostic and treatment decision making processes, improving the standard of care whilst reducing expenditure. Breast cancer is the second leading cause of cancer-related death in women there are 1.7 million new cases of breast cancer occur each year, with a global economic burden estimated at US$88 billion. A woman's chance of survival is significantly increased with early detection. The mammography technique has major limitations and fails to detect approximately half of cancers in women with dense breast tissue. Women with dense breast tissue have a 4 to 6 times increased risk of breast cancer compared to women with non-dense tissue. Unfortunately the group at highest risk of cancer is also the group for which mammography is least effective. Tiro Medical have developed a breast imaging device (the OE scan) based on the use of Optical Elastography and Digital Physiological Analysis. The Tiro solution has higher contrast ratio in dense tissues allowing for improved diagnosis in this population, uses zero radiation so is not limited by age and can be used at any age and in any condition (pregnancy, specific illness etc.) and has zero pain leading to better compliance. The company is currently in talks with potential stakeholder companies in the EU who have shown an active interest in the project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'National Contact Points for quality standards and horizontal issues' (2014-2020).

assistant: **Concept**

National Contact Points (NCPs) will play a key role in Horizon 2020 as providers of information and assistance to potential applicants and project beneficiaries. They constitute the main interface to the European R&D community for Member States and Associated Countries and the European Commission. While their activities are underpinned by the European Commission’s “Guiding principles for setting up systems of national contact points”, NCPs are appointed and financed at national level so that existing NCP systems show a wide variety of architectures and ways of working. This project aims to create and implement a new and integrated training of Horizon 2020 advisors – the NCP Academy. It brings together NCP Coordinators and NCPs for Legal and Financial aspects of Horizon 2020 to develop the NCP Academy concept and to develop and implement training courses on cross-cutting issues. It addresses quality standards and good practice as well as routes to feedback and communication for this community. In doing so it aims to significantly enhance the performance of NCPs and does so by harnessing the knowledge base already existing within this community. It will be responsive, addressing new issues that emerge during implementation of the Horizon 2020 programme and it will be all-inclusive, providing training to all NCPs, and especially targeting new and/or less experienced NCPs. The consortium will work closely with existing thematic NCP Networks, carefully serving their needs for cross-cutting aspects of Horizon 2020. Expected impacts include achievement of an improved and professionalised NCP service across Europe, thereby helping simplify access to Horizon 2020 calls.


**Keywords:** National Contact Points,  Training,  Cross-cutting Issues
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Global Model and Observatory for International Responsible Research and Innovation Coordination' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The RESPONSIBILITY project aims to create a network of stakeholders that would adopt and diffuse a common understanding in Responsible Research and Innovation between different actors in Europe and around the globe.  In doing so it will develop a model and provide a tool for international cooperation, the RESPONSIBILITY Observatory, involving the societal, policy and research stakeholders to these activities. It intends to provide practical means and structure a crucial interaction between society and research, providing a set of recommendations and tools to policy makers and active RRI stakeholders in order to take the necessary measures to nest responsible research and innovation into products and services from the very beginning (“efficient RRI by design”).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Circularly-polarized light detection from achiral materials by optically programmable transient IR-induced chirality'.

assistant: **Objectives**

Detection of circularly polarized light (CPL) currently relies on polarization-insensitive photodetectors combined with bulky chiral optics. This limits their sensitivity, scalability and integration into modern optoelectronic technologies. This project will establish a fundamentally new photonic route to enable CPL detection by achiral organic and perovskite materials through mid-infrared excitation of vibrational modes that transiently break local symmetry to induce chirality. This will be achieved through a novel spectroscopic method that uses a mid-IR pump pulse to drive symmetry-breaking vibrational modes, inducing transient chirality, followed by a circularly-polarized probe to generate photocurrent, thereby enabling determination of the photocurrent dissymmetry factor, which measures a photodetector’s ability to distinguish left- and right-handed CPL. The major objective is to demonstrate non-zero dissymmetry factors from achiral materials for the first time via this photonic approach. Subsequently, by mapping the dissymmetry factor across a library of organic and perovskite single crystals, the project will identify the key structure-property relationships that enable sensitive CPL photodetection from achiral materials to engineer the best-performing devices.The implementation of this proposal will exceed state-of-the-art photodetection technology and align with EU priorities in photonics, quantum technologies and advanced materials, while delivering transferable expertise and practical skills in spectroscopy and device engineering, propelling my trajectory toward independence. Demonstrating achiral CPL detectors and developing the novel spectroscopic method used to test them will expand our fundamental understanding of the role of chirality in light-matter inte
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Safety in NanOmaterials & NAnotechnology', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The potential of nanomaterials and nanotechnology to improve the quality of life, to address society’s grand challenges and to contribute to economic growth and to sharpen the competitiveness of industry is now widely recognized, not only in Europe, but globally. Nanomaterials and nanotechnology offer substantial possibilities for improving the competitive position of the EU and for responding to key societal challenges. However, there is a need to ensure the safe development and application of nanomaterial and nanotechnologies and for finding reliable ways to predict the potential risks to health, food and environment of these materials and technologies . Due to the widespread use of nanomaterials, it is critical to identify any potential risks they may pose to human health or the environment. These current uncertainties surrounding nanomaterial risk mean that research is required into nanomaterial safety. Addressing these knowledge gaps will help to ensure that innovation in the rapidly developing area of Nanotechnology is not stifled by concern, but instead by determining risks associated with nanomaterials we can promote the safe, sustainable and responsible use of this technology.SiNfONiA aims at attracting and maintaining a high profile researcher (ERA Chair) and respective research team with excellent research capabilities in the nanosafety research domain. SiNfONiA will play as a catalyst to fully maximise the impact of the ERA Chair on the scientific excellence and research performance of the International Iberian Nanotechnology Laboratory (INL).


**Keywords:** Nanotechnology, Nanomaterials, Nanosafety, Nanocharacterization, Nanotoxicity, Health Risks, Exposure, Predictive Descriptors,  Increased Research Capacity, Scientific Excellence
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Study of improved models for describing the propagation of light waves in nonlinear inertial media'.

assistant: **Objectives**

The project aims to give improved models for the study of optical pulse propagation in the strongly non linear regime with applications to optical fibers and bulk media. It is also intended to study the propagation of ultrashort and intense spatio-temporal pulses in a nonlinear media taking into account the rotational nature of light. One of the parts of this project includes the development of two main numerical codes for the simulation of (a) the forward propagating rotational electromagnetic wave in the paraxial approximation (vectorial BPM) and (b) the time domain evolution of TE and TM modes using Maxwell equations and a single dynamic model for the inertial response at the medium. A systematic comparison of the new results from the known theory based on scalar models will be undertaking using analytical techniques, mainly variational methods.