RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'A quantum chemical approach to dynamic properties of real materials' (CC4DYN).

assistant: **Innovation**

Computational materials science, using ab initio simulations and high-performance computing, is expected to play a key role in realizing the vision of ‘materials by design’. However, the goal to discover game-changing materials with scientific and industrial relevance requires highly accurate ab initio methods for excited state as well as ground state properties of atoms, molecules and solids. So far, due to the computational complexities involved, methods with systematically improvable accuracy for condensed matter systems, such as coupled-cluster theories, are mostly limited to the study of ground state properties in the clamped-nuclei approximation. This ambitious proposal aims at inducing a computational paradigm shift in the study of vibrational and optical properties of real materials by implementing a multitude of novel methods. On the one hand, we propose to reduce the computational cost of time-dependent equation-of-motion coupled-cluster theory by several orders of magnitude compared to existing approaches. On the other hand, coupled-cluster atomic forces will be implemented for machine-learning force fields in the Gaussian approximation potentials framework. Together, the proposed methods have the potential to achieve an unprecedented level of accuracy and system size for the prediction of a wide range of material properties including optical spectra and phonon frequencies. We seek to employ the newly developed approaches to resolve a number of long-standing discrepancies between theoretical predictions and experimental findings for dynamic properties of defects, molecular crystals and layered materials. These carefully selected systems highlight key problems of currently available ab initio methods and novel approaches that go beyond the state of the art wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Moonshine and String Theory' in the context of a Horizon 2020 call.

assistant: **Objectives**

The purpose of the proposed research is to forward the understanding of the umbral moonshine discovered recently by myself. I plan to study it in the context of string theory. Moreover, I aim to use this new discovery to gain a deeper understanding of certain fundamental aspects of the theory. The term moonshine refers to the astonishing and puzzling relation between functions with special symmetries (modular properties) and finite groups. The novel type of moonshine involves the so-called mock modular forms, and was first noticed in the study of K3 surfaces. In a recent paper I constructed 23 instances of such a new ""umbral moonshine"" phenomenon  in a completely uniform way using the 23 special lattices classified by Niemeier as the starting point, and thereby provided the general framework in which this paradigm should be studied.  From a physical point of view, it is well-known that K3 surfaces play a crucial role in not only the specific constructions of compactifications but also the fundamental dualities in string theory. Hence, the new quantum symmetries of K3 surfaces, as suggested by umbral moonshine, will have a wide range of important implications for string theory. Moreover, I believe the solution of the moonshine puzzle will lead to a new understanding of the long sought-after algebraic structure of the supersymmetric (or BPS) spectrum of supersymmetric quantum theories. More ambitiously, I aim to draw lessons from these special theories with large symmetries to shed light on the structure of the ""landscape"" of string theory vacua. From a mathematical point of view, to understand and to prove such a mysterious and beautiful relation would be a triumph in its own right. Moreover, the development of umbral moonshine will undoubtedly lead to new important
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Interdisciplinary training network on the purinergic P2X7 receptor to control neuroinflammation and hyperexcitability in brain diseases.' (PurinesDX).

assistant: **Innovation**

Brain disorders affect ~179 million people and their families in Europe alone, with an annual cost to the taxpayer estimated at €800 billion- a greater economic burden than cardiovascular disease and cancer combined. Despite diverse etiology, overlap in clinical symptoms and comorbidities between brain disorders suggests shared patho-mechanisms. In particular, hyperexcitible states driven by glial activation and neuroinflammation appear near ubiquitous. Targeting these mechanisms offers the potential to ameliorate symptoms and reverse disease progression across a broad span of brain disorders. Functioning as a gatekeeper to neuroinflammation and mechanistic link between neuronal hyperexcitability and glial activation, the ATP-gated, ionotropic purinergic P2X7 receptor (P2X7R) offers the most promising target for pharmacological intervention in the neuroinflammation-hyperexcitability pathway, to date. With breakthroughs in understanding P2X7R function, highly promising effects demonstrated for antagonists in models of brain disease and vast investment in P2X7R-related drug development programmes, now is the perfect time to pool resources. PurinesDX brings together global leaders in translational research in purinergic signalling, Europe’s leading clinical specialists in a broad range of brain diseases, and industrial partners specializing in drug and biomarker development. Sharing unique genetic tools, newly developed diagnostic devices and novel, selective and brain-stable P2X7R antagonists, the synergism facilitated within PurinesDX will extend to the training of an urgently needed new generation of highly skilled, innovative, creative and entrepreneurial scientists. Alongside the provision of this interdisciplinary, international and intersectoral environment, an orig
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Parallel computing based on designed networks explored by self-propelled, biological agents'.

assistant: **Objectives**

Many technologically and societally important mathematical problems are essentially intractable for traditional, serial computers.  Therefore, a significant need exists for parallel computing approaches that would be able to solve such problems faster than current serial computers. This project will develop and benchmark a novel paradigm for future parallel computing approaches, based on biological entities. Specifically, we will encode mathematical problems into networks consisting of nano- or microsized channels and nodes, and will use self-propelled biological agents to explore these networks and find the solution to the encoded mathematical problems. Due to the very large number of agents, the problem is solved in a highly parallel manner. A number of different types of micro- and nanoscale biological agents will be used, including innate objects (protein filaments propelled by molecular motors) and living systems (bacteria and fungi). The novelty of this approach lies in the use of self-propelled agents (avoiding scalability issues associated with the use of external driving forces), as well as in the combination of human intelligence (in the target-oriented design of networks) with the parallelism enabled by large numbers of biological agents. Key aims of the project will be the benchmarking against existing computational approaches, and the identification of application areas where this novel paradigm may lead to transformative applications. Benefits to society will include the ability to solve hitherto intractable problems, and the development of a sustainable and energy-efficient computing approach that is radically different from current ICT technology.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Improving the eXperience of musicians and spectators with digital Musical Instruments using 3D interfaces and mixed-reality technologies' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Art and science intersect often and in many ways. In particular, new technologies are hacked for the purpose of building musical instruments. As a result, more and more novel digital musical instruments come out of laboratories and companies and are used in public performances. However, the variety and quality of chosen interfaces, sound synthesis methods and mappings between gestures and sounds often prevent people from understanding and enjoying those instruments as much as familiar acoustic or electric instruments based on physic principles.The purpose of this project is to improve the experience of both novices musicians and spectators with digital musical instruments, by combining work on 3D graphical musical interfaces and advanced musical techniques by the Fellow with research on mixed-reality displays and audience experience by the Host Institute.A first phase will focus on highlighting the impact of musicians gestures and the behaviour of instruments using 3D representations spatially merged with the instruments. The effects on the experience of spectators during public performances will then be evaluated.A second phase will explore the concept of adaptive mappings by means of graphical and musical level-of-detail and differentiated views using multi-user displays in order to ensure an enjoyable playing experience for all musicians regardless of their expertise level. A long-term user study will be conducted in order to evaluate the impact of the proposed solutions on musicians experience during the learning process.Both phases will involve dissemination parts including workshop with artists, academic publications and workshops, demonstrations and concerts for the general public, release of software components under accessible licenses, and online guides for bu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Predicting the emergence and transmission in Europe of drug resistant HIV', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

During the past ten years significant progress has been made in the treatment of HIV-infected patients. Unfortunately, this success is jeopardized by the emergence and spread of drug resistant HIV. Although a considerable proportion of patients carries a drug resistant virus, there is still only limited evidence that drug resistance leads to rapid clinical progression. But in the next years, the emergence of complex drug resistant viruses that are difficult to treat can increase.A major public health concern is that these drug resistant viruses can be transmitted to newly infected individuals. In the current project, a mathematical model will be constructed that includes the complexity of drug resistance. The model aims to timely predict the future trend, and key factors explaining the emergence and transmission of drug resistant HIV. The results of the model will be of use to public health authorities, the clinical community, pharmaceutical industry and patient populations to prevent the further emergence and spread of drug resistant HIV.The present project offers a unique opportunity to combine Europe's leading role in the epidemiology of drug resistant HIV with the knowledge of a renowned expert in the field of mathematical modelling resistant HIV. The outgoing phase of this project will take place at the department of biomathematics of the University of California at Los Angeles (UCLA) AIDS institute. This department is internationally acclaimed for its work on mathematical modelling of drug resistant HIV. During the return phase the acquired knowledge will be applied at the department of virology of the University Medical Centre Utrecht, the Netherlands. This department is the successful coordinator of several European research networks on drug resistant HIV.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Turning cosmic shear into a litmus test for the standard model of cosmology' (COSMIC-LITMUS) targeting Horizon 2020.

assistant: **Abstract**

The standard model of cosmology is impressively consistent with a large number of observations. Its parameters have been determined with great accuracy with the Planck CMB (cosmic microwave background) mission. However, recently local determinations of the Hubble constant as well as ob- servations of strong and weak gravitational lensing have found some tension with Planck. Are those observations first glimpses at a crack in the standard model and hints of an evolving dark energy com- ponent? With this ERC Consolidator Grant I will answer these questions by greatly increasing the robustness of one of those cosmological probes, the weak lensing effect of the large scale structure of the Universe also called cosmic shear.In order to reach this goal I will concentrate on the largest outstanding source of systematic error: photometric redshifts (photo-z). I will exploit the unique combination of two European imaging surveys in the optical and infrared wavelength regime, an additional narrow-band imaging survey with extremely precise photo-z, and spectroscopic calibration data from a recently approved ESO large program on the VLT. Using angular cross-correlations and machine-learning I will calibrate the photo- z in a two-stage process making sure that this crucial systematic uncertainty will keep pace with the growing statistical power of imaging surveys. This will yield an uncertainty on the amplitude of the clustering of dark matter that is smaller than the best constraints from the CMB.I will also apply these methods to ESA’s Euclid mission launching in 2020, which will fail if photo-z are not better understood by then. If the discrepancy between lensing and CMB measurements holds this would potentially result in a revolution of our understanding of the Universe. Regardl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Hypermedia'.

assistant: **Innovation**

Main Objective HYPERMEDIA will investigate the handling and delivery of continuous multimedia (audiovisual) material in a hypermedia service environment. Such an environment allows users to navigate in hyperspace and explore databases owned by the various players in the service chain (content providers, network providers, service providers etc). HYPERMEDIA's users will be professionals - the communications and media organisations who are the service providers for the general public. User requirements are evolving and the most significant development is demand for improved navigation techniques. This implies that multimedia services will have to evolve into hypermedia services. HYPERMEDIA will develop video indexing tools that increase the possibilities for interactivity. Service providers and other professional users will be able to use these tools on their audiovisual materials to offer improved navigation and search facilities. There is a clear market opportunity for services that handle and deliver continuous audiovisual materials. This 'continuous audiovisual market' will have a value chain of services. HYPERMEDIA will demonstrate a solution addressing all aspects of this market (metadata, video indexing tools, databases architecture, network architecture, Intellectual Property Rights services) and develop an exploitation plan based on the results of its trial. Technical Approach HYPERMEDIA's technical approach consists of the following activities:  -The definition and implementation of a database architecture and internal data structure for audiovisual materials, which will optimise access and navigation capabilities in a client-server environment. The navigation facilities will rely on WWW technology and gateways to DBMSs; using descriptors (registration cards), w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Ship thermal insulation project' (STIP).

assistant: **Innovation**

The scientific and technical objectives of this research proposal concern the determination of characteristics and application of the Thermoshield" topcoat in a maritime environment. Research is required to determine thermal insulation characteristics, application requirements, establishment of the optimum coating thickness and maintainability of the topcoat material. An economic impact assessment will also be carried out. "
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Mechanical contribution of starch granules in the stabilization/destabilization of cell walls during bread baking'.

assistant: **Innovation**

Wheat-based bread is a staple food in the European and North American diet, presenting a relevant economic importance. Early successes in the wheat selection (high in gluten) along with the use of additives (surfactants, supplementation in gluten) to smooth out the variability in batch-to-batch performance of wheat flours reduced the incentive to carry out in-depth characterization of the roles played by other flour ingredients in the inflation process during bread baking. However, supplies of bread-quality wheat are being threatened by climate-induced variability, while consumers are more critical regarding the use of food additives and more demanding of clean-label products. In this scenario, the bakery industry will demand a transformation and alternatives such as flour blending will become a hot topic. In order to obtain breads with similar performance, it is crucial to understand the exact role played by flour ingredients other than gluten in breadmaking, especially starches (~80% of the wheat flour). In this context, the MECASTARCH project proposes a cutting-edge approach of computer modelling offering the possibility to decouple the multiple roles played by starch in the stabilization/destabilization of Gas Cell Wall (GCW) during baking and focusing on the mechanical contribution of starch. Several experimental approaches applied to a selection of starches will feed this computer modelling, including rheometry on moderately hydrated starch, starch/gluten interactions by AFM, and morphometric observations of GCW by sophisticated microscopy. On the one hand, the fellow will share her large experience in the characterization and evaluation of starches with the host. On the other hand, the host will contribute to develop her scientific skills related to material scie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Analysis Tool for Mesh Design of Leading Edge Design of Integrated Circuits' (MeshAnalyzer).

assistant: **Concept**

EDXACT (Electronic Design Automation: Extraction Analysis and Control Tools) is a software editor producing software tools that are necessary for the design of leading edge integrated circuits (IC). EDXACT is a supplier of Apple, Samsung, Huawei, Intel, AMD, TSMC and many other companies that supply the world with products containing advanced integrated circuits. The design of circuits with several tens of millions of transistors has become a normality over the last decade. The feature sizes of leading semiconductor circuits vary from 28nm downto 10nm and are extremely small. The design automation tools proposed by the oligopoly of the major suppliers of the market are lagging behind the technical possibilities. One of the most important aspects is the clock-design, where as much as 40% of design time could be saved by switching to modern tools. More importantly, by changing to a slightly different design approach and using a mixture of a clock-tree and clock meshes, today’s circuits could save energy by more than 35%. Unfortunately, no commercial tools exist today capable of analysing clock meshes correctly. Designers are limited to manual design and internal tools, which is limiting the use of this technology.We see an important market opportunity for EDXACT by combining our existing technology with existing tools and some intelligent glue in order to create the sought-after mesh analysis tool. Being in direct competition with the leaders of the market, we intend to progressively displace the usage of the monopolistic tool for timing analysis. Phase 1 of the project will put in place the prototype, including documentation and marketing material, finalize an official partnership with two leading IC manufacturers, and will clarify the business plan for this interesting