RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Data Usage Control for empowering digital sovereignty for All citizens' (DUCA).

assistant: **Concept**

Driven by the growing concern on the usage of personal and sensitive data in the Internet, DUCA aims at providing a framework to empower European users and organizations to take control of their data, thus easing confidentiality and personal data protection (including both personal data of citizens and confidential data produced by data-enabled organizations). This unified framework of security and privacy-enhancing solutions incorporates a set of building blocks to support the development of a modular architecture and reference implementation that will also include techniques for measuring privacy risk exposure. To be general and flexible, the main components will be designed as platform independent to ensure the compatibility of the DUCA framework with the many architectures and deployment models of the IoE.In order to achieve this, DUCA has the following concrete objectives:Objective 1: To build a flexible and easy to use distributed framework for managing data sharing agreements, which will empower users to control the usage of their data.Objective 2: To develop and integrate several security and privacy enhancing technologies and to tailor these to the specific needs of the DUCA platform and use cases.Objective 3: To deploy and validate the overall distributed data usage control framework in several use cases. Within the DUCA consortium, we have identified the following three use cases as relevant samples to showcase our framework: Smart energy, Usage control for Big Data and Artificial Intelligence, and Collaborative mobility. Several stakeholders will benefit from the awarding of DUCA, including the seconded staff members, who will increase his/her knowledge and career opportunities, beneficiaries will improve their research and innovation activities, and overall
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'RESEARCH INFRASTRUCTURE TRAINING PLUS' (RItrainPlus) targeting Horizon 2020.

assistant: **Abstract**

Research Infrastructures (RI) are standing pillars for excellence in science and a vital element for the realization of the European Union as a knowledge-based society. Together with Core Facilities (CF)- existing in many universities, academic research centres and national nodes of distributed RI- RI are also major actors in the implementation of the EU Open Science and Open Innovation strategy and a major factor for its success. As RI and CF increase in importance, questions about how to organize, maintain, manage and finance them have become a major topic for funding and research organisations. This proposal brings together, for the first time, RI, CF and European universities, in a new innovative concept to transform the access and empowerment of human resources for national and international scientific facilities in Europe. The overarching goal of RItrainPlus is to design and deliver a training programme to fulfill the competency requirements for the current and future managers of European RI and CF. RItrain Plus will:i) drive excellence, operational improvements and long-term sustainability of European RI and CF by developing: formal learning activities: executive post-graduate courses; learning on the job: staff exchange, with a short-term mobility programme at different RI/CF locations; peer learning: a Community of Practice, within all RI and CF, able to promote existing excellence and experience, and share knowledge; ii) create a foundation for the long-term provision of highly qualified personnel for managing RI and CF by developing Learning Activities embedded in existing university programs and a certifiable European Longitudinal Learning Track; iii) establish a permanent and self-sustainable European School for Management of Research Infrastructures. In th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'European Integration, Regional Convergence, Location of Industrial Activity and Labour Markets Adjustment' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

This EuroConference will focus on the impact of European integration on regional convergence, location of industrial activity and labour markets adjustment in both EU member states and accession countries. The overall objective is to bring together established and young researchers as well as policy makers and discuss issues of actual importance in both current and future European Union member states.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Production of next generation modulators of pannexins and connexins as novel therapeutics in the treatment of inflammatory cardiovascular and hepatic diseases.'.

assistant: **Concept**

The modulation of membrane-bound proteins by drugs is receiving increasing attention from both academia and industry. Among such proteins are pannexin1 (Panx1), connexin43 (Cx43) and connexin32 (Cx32) that form hemichannels at the plasma membrane surface. These hemichannels mediate cellular communication and have emerged as key players in inflammation. This carries translational relevance, as hemichannel inhibition could represent an innovative strategy for the treatment of a plethora of diseases. However, a hurdle in clinical exploration is the lack of appropriate hemichannel inhibitors. PANACHE therefore is a timely project, as it will generate a new type of Panx1, Cx43 and Cx32 hemichannel inhibitors. As proof-of-concept, the generated Panx1, Cx43 and Cx32 hemichannel inhibitors will be tested for their potential to alleviate pathological features in animal models of inflammatory diseases in the cardiovascular system and liver. This will be accomplished by joining academic and industrial scientists from the chemical, chemo-informatics and biomedical fields as well as by relying on in vitro and in silico studies, animal experimentation and testing human material. PANACHE will allow taking a leap forward to the realization of its long-term vision, namely the production of metabolically robust and selective Panx1, Cx43 and Cx32 hemichannel inhibitors that can be used for the establishment of a generic approach to synergize current therapy of hard-to-treat inflammatory diseases. Hence, PANACHE is a foundational project, laying the basis for follow-up initiatives to scrutinize the versatile anti-inflammatory therapeutic actions of the Panx1, Cx43 and Cx32 hemichannel inhibitors.


**Keywords:** Cellular communication, pannexin, connexin, peptide, peptidomimetic, treatment
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Application of new technologies and methods in nutrition research – the example of phenotypic flexibility' (NUTRITECH).

assistant: **Concept**

NutriTech will build on the foundations of traditional human nutrition research using cutting-edge analytical technologies and methods to comprehensively evaluate the diet-health relationship and critically assess their usefulness for the future of nutrition research and human well-being. Technologies include genomics, transcriptomics, proteomics, metabolomics, laser scanning cytometry, NMR based lipoprotein profiling and advanced imaging by MRI/MRS.All methods will be applied in an integrated manner to quantify the effect of diet on “phenotypic flexibility”, based on metabolic flexibility (the capacity for the organism to adapt fuel oxidation to fuel availability). However, NutriTech will move beyond the state-of-the-art by applying these integrated methods to assess the underlying and related cell biological and genetic mechanisms and multiple physiological processes of adaptation when homeostasis is challenged. Methods will in the first instance be evaluated within a human intervention study, and the resulting optimal methods will be validated in a number of existing cohorts against established endpoints.NutriTech will disseminate the harmonised and integrated technologies on a global scale by a large academic network including 6 non-EU partners and by providing an integrated and standardised data storage and evaluation platform. The impact of NutriTech will be multifold and exploitation is crucial as major breakthroughs from our technology and research are expected. This will be achieved by collaboration with a consortium of 8 major food industries and by exploitation of specific technologies by our 6 SME partners. Overall, NutriTech will lay the foundations for successful integration of emerging technologies intro nutrition research.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Online Humanities Scholarship: A Digital Medical Library based on Ancient Texts' (DIGMEDTEXT) under Seventh Framework.

assistant: **Objectives**

The project aims at providing electronic editions of ancient medical sources including texts, translations, commentary, metadata, and images of papyri, ostraca, and tablets. Greek medical papyri and related artifacts recovered in Egypt are a veritable treasure trove of information on crucial and otherwise poorly attested phases in the development of ancient Greek medicine, its penetration into regions of the Mediterranean world and its transformation through interaction with local medical traditions — a medicine that Romans spread throughout western Europe. The interdisciplinary approach makes possible cooperative interaction among classicists, information technicians, ancient historians, and especially historians of medicine. The goal is to make both texts and metadata accessible via a single interface and to publish texts online, combining philological rigour with technological flexibility, bibliographic control, and a critical apparatus for each text. Openness and dynamism will characterise our searchable database: it is not to be a synthesis of fixed data, but rather a constantly changing repertory of sources monitored by the scholarly community and maintained by those who wish to participate at a professional level. It will extend the Duke Data Bank, taking the latter in new directions by uniting documentary and literary papyri into a common technological framework — SoSOL within Digital Papyrology. The central feature is interaction by the worldwide community of coopted participants manipulating electronic means to produce new editions of previously unknown literary and paraliterary texts of medical content, as well as to improve existing editions. The Medical Library will share space with a dictionary of technical terms attested in the papyri that likewise surviv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'New gtl based on low temperature cpo (LTCPO-GTL)' (LTCPO-GTL) targeting Fifth Framework.

assistant: **Abstract**

Clean liquid transport fuels from natural gas can be obtained through different procedures. In this proposal a new and innovative approach will be investigated coupling auto thermal catalytic partial oxidation of natural gas at relatively low temperatures to produce the synthesis gas and a Fischer-Tropsch reaction system. The intended innovative developments will include more active and stable catalysts for both stages. It will also consider the application of advanced membrane technologies to build special water selective membrane modules able to continuously extract water from the FT reaction system. From the preliminary results at lab scale the most promising catalysts and membrane modules will be tested at semi-pilot scale to gather the required information for the technical and economical assessment of the new process.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Genetics of human hair form diversity' (HairGen) under Horizon 2020.

assistant: **Objectives**

One of the key challenges in human genetics is to understand the genetic architecture of phenotypic traits. Hair comprises a distinct part of one’s physical identity and its form varies across and within populations. Despite the significant progress made by genome-wide association studies (GWAS), much of the human hair variation remains unexplained. Therefore, a comprehensive study focused on uncovering genetic determinants of human hair form is needed. The aims of the present project are three fold. First, to use self-reported hair forms as a paradigm to perform in-depth macroscopic and microscopic analyses focusing on hair dimensions that may vary across major hair forms. Additionally, curliness of hair samples will be quantified. Second, to perform a genome-wide association study to identify loci underlying contemporary variation in hair form. To this end, we have hair samples from ~2,700 participants collected from a diverse set of populations and genotypes for >600,000 SNPs. Third, to select the most promising of the identified variants for functional analysis and use the cutting-edge technology of CRISPR/cas9 genome editing in mice to evaluate the hair phenotypes. This will be further complemented with assessment of their skin via histological methods to study the structural and developmental changes associated with the variants. The project will help to refine the available methods for classification of hair form and identify some of the genes underlying variation in hair form. Most importantly, HairGen will use the novel approach of genome editing in mice to investigate the functional role of the variant, thereby contributing to broader knowledge in the field. This proposal brings together a fellow with relevant background in study of phenotypic trait together w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Design and Expansion Turbine for Domestic Refrigerators and Freezers' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

This proposal for a Marie Curie Intra-European Fellowship for Career Development is meant for the training of a research fellow from Spain in the laboratories of BSH Bosch und Siemens Hausgeräte GmbH, (BSH), Germany, the largest home appliance manufacturer in Europe. The goal of the DETforDRF 2.0 project is to explore the required expansion mechanism in a cooling circuit of a household refrigerator in order to increase the efficiency of the system and the utilization of the released energy in the expansion process. The proposed research-training activities will be done in an industrial context and will cover the science, technology and business value chain. The training will start by applying relevant fundamental principles of the physics of fluid dynamics, followed by the design and construction of a turbine, based on an innovative concept to decrease the energy consumption of refrigerators and freezers, and ends with a market study to explore the possibility of mass production of the newly developed concept. The innovative concept relies on the expansion mechanism that is realized through the capillary tubes and permits the transformation of the energy of the system that will be lost otherwise, to a useful energy that will be used to increase the heat transfer coefficient in the cooling circuit. The project is focused on refrigerators, but the concept could be generalized to other applications, such as air-conditioners, and would generate insights on the recuperation of wasted energy for applications in other domains.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Nanowired Scaffolds for Cardiac Tissue Engineering' in the context of a Seventh Framework call.

assistant: **Objectives**

Ischemic heart disease (IHD) is the most common cause of death in the Western world, accounting for more than 741.000 deaths each year in the European Union with yearly costs in excess of € 45 billion. Myocardial infarction (heart attack; MI) captures a significant segment of IHD population and is associated with sudden death as well significant morbidity and mortality.  Currently the only cure for end-stage heart failure is cardiac transplantation. As cardiac donors are scarce, there is an urgent need to develop new strategies for regeneration. One experimental approach to treat defected organs is tissue engineering. Engineered cardiac patches to replace scar tissue after MI are produced by seeding cardiac cells within 3D biomaterials. However, success of this approach can be jeopardized by a lack of supporting microenvironment for the organization of a thick tissue and lack of electrical conductivity within the construct, both leading to impaired electrical signal propagation. Another limitation is the lack of an appropriate cell source. In the current proposal we first aim to engineer a 3D microenvironment mimicking the natural ECM of the myocardium. This synthetic matrix will be embedded with gold nanowires to increase electrical signal propagation between cardiac cell bundles. In the second step the ability of this unique microenvironment to support the culture and organization of human cardiac stem cells to a functional mature tissue will be explored. Finally, we will investigate the potential of the nanowired cardiac patch to improve the infarcted heart function. The proposed study has a potential to present a breakthrough in tissue engineering, and could help develop conductive cardiac patches to replace scar tissue after MI and repair congenital heart diseases.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'THE PRESERVATION OF FROZEN FOOD QUALITY AND SAFETY THROUGHOUT THE DISTRIBUTION CHAIN' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

Across the European Union much research is being carried out on by industrialists and academics on the improvement of quality and safety in frozen foods. A key problem for all this research is how to maintain and monitor factors affecting this quality from the time when the food leaves the factory until the point of consumption. The range of disciplines involved in this field is extremely broad. This proposal is for a concerted action to bring together the key players in this research. The concerted action aims to provide a focus from which information on the current state of research can flow to the widest possible audience, to prevent duplication, and to coordinate future research direction.Scientific research and development is currently approaching the quality preservation problem from two angles. The first is to monitor and control temperature during distribution and retail to minimise damage. An ideal world would see foods frozen to a storage temperature below the glass transition temperature and maintained at that temperature until the time of cooking. However practical considerations of handling, easy access to, and visibility of, displays and economic factors all compete with this ideal. The second approach is to engineer foods so that they are less susceptible to poor thermal handling in the distribution chain. This is approached through research on modification of the glass transition in the unfrozen solution, in order to minimise chemical deterioration, and on the reduction of ice recrystallisation damage, by the study of antifreeze peptides. The main objectives are : 1. To establish a multidisciplinary network to coordinate future research in this area.2. To ensure the information and involvement of as many as possible of the SME's which make up a large fra