RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Computational genomics of long noncoding RNA domains across metazoans' to be submitted under Horizon 2020.

assistant: **Abstract**

From junk DNA to genomic dark matter, the road to understanding RNAs that do not encode for proteins has been full of surprises. Compared to 19,000 protein-coding genes, recent estimates point that our genome contains between 25,000 and 100,000 long noncoding RNA (lncRNA) genes. Far from being inert, some lncRNAs are involved in development and disease, particularly, cancer. It has also been shown that the function of a lncRNA can be associated with its localisation in subcellular compartments. Nevertheless, to experimentally characterize and validate interesting lncRNAs is an arduous task. Computational approaches based on machine learning could be designed to complement and scale-up such efforts. Based on recent experimental discoveries, it has been proposed that lncRNAs are separable into functional domains, and that these domains are intimately related to transposable elements and repeats. Nevertheless, how functions are encoded in primary RNA sequence is a fundamental unsolved problem. I propose to develop the first high-throughput computational approach to map lncRNA domains across metazoan genomes. Domains will be first identified according to statistical evidence supported by current biological insights. Putative domains will be queried against state-of-the-art databases on lncRNA function, localisation, and disease. Machine learning algorithms will then be employed to predict new functional domains, and new mechanistic insights will be offered for promising candidates. Lastly, the obtained maps will be stored and disseminated in a database, that will be regularly updated and readily accessible for the research community. This will be a foundational resource to finally shed light on the role of lncRNAs, their regulation and involvement in disease.


**Keywords:*
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Austro-German exile in America 1930-45: interrogating the relationship between science, technology and modern selfhood in cultural and musical discourses.' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

This project examines the relationship between technology, selfhood, and modernity in the context of the music and thought of Austrian and German émigré musicians and cultural theorists in America from 1930 to 1945. The project looks beyond the boundaries of the nation state and the nexus of composer and musical work that tend to structure musicological enquiry. Instead, transnational historical methodologies will be used alongside primary archival research to join a timely conversation in musicology about the intersections between histories of music and science. In the era 1930-45, (Austro-)Germany and America were scientific powerhouses. Against the backdrop of mounting political turmoil, both generated ethically controversial scientific and technological research simultaneously liberating and malevolent: atomic technology, cosmology, radar, eugenics, transportation innovations. Technology necessarily shapes ideas of selfhood, and the mass displacement of Austrian and German intellectuals to the US after the rise of the National Socialists created a ‘culture of exile’ in which, as émigrés integrated within the new context, diverse attitudes to the relationship between science, technology, and formulations of the self began to interweave. Using musical collaborations, spectacles, and events to illuminate and explore the range and ambivalence of those attitudes, the project will furnish a more finely grained historical understanding of the disconnections between Germanic and American relationships to technology and selfhood in the period. The research outcomes during the fellowship will be a monograph, and two articles as part of substantial work on a second book. A further key objective will be to establish an international interdisciplinary academic network in the US,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Development of a central information platform for ERA NETs under ERAWATCH: Preparatory phase, NETWATCH' (NETWATCH).

assistant: **Innovation**

This project is designed as a preparatory phase to explore and inform interested parties such as the European Commission and the Member States about opportunities to develop a central information platform for ERA NETs under ERAWATCH. The set up of a central information platform was one of the key recommendations of an expert group who evaluated the ERA NET scheme under FP6. The concept of the project includes a three step approach: 1) build a series of scenarios on how to present ERA NETs within ERAWATCH, 2) provide an  analytical framework about the role of the ERA NETs and joint initiatives stemming from ERA NETs for further implementation of the ERA, using ERA NETs as indicators of its development, and 3) develop a participatory method by which a core group (advisory board) including ERA NETs coordinators, ERAWATCH Network Members, the EC and other relevant actors is closely attached to the project from its onset until its end, hereby ensuring that the needs of users are integrated and facilitating the implementation of the project from its preparatory to its potential operational phase. The overall strategy of this project has been set up as a preparatory phase over 12 months. It will provide evidence on the necessary information to identify the most appropriate set-up and management scheme for a central information platform on ERA-Nets under ERAWATCH. The strategy of this project is to develop in a transparent and participatory manner potential scenarios for the set-up and management of a central information platform on ERA-Nets within ERAWATCH. The information platform will improve mutual learning among ERA-Net participants and provide R&D policy makers on EU and Member State level with relevant information about efficiency, effectiveness and impact of ERA-Nets an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Three-Dimensional Imaging of Selective Particle Storage in Nanocapillaries' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Precise manipulation of colloidal particles is essential to foster nanotechnology applications in chemistry, materials, biology, and devices. Fundamental insights into their dispersion, assembly, and reactivity, enable precise engineering of advanced materials and the development of innovative nanoscale devices, thus revolutionizing fields ranging from catalysis to electronics. For instance, colloidal particles with antagonistic electrophoresis (DEP) properties can be selectively inserted into a nanocapillary. When considering nanoparticles as carriers of data in a medium like water, arranging them in a specific sequence in the nanocapillary enables data storage. The feasibility of this particle storage relies on the ability to visualize and manipulate the nanoscale motions of the nanoparticles. One of the most sensitive and accurate ways to track particle movement is by monitoring individual particle fluorescence in optical microscopes, which is crucial for non-invasive imaging of particles in any colloidal environment. SPS_Nano aims to develop a three-dimensional dynamical imaging method to track and understand the controlled motion of nanoparticles using dielectrophoresis. This colloidal data storage is an alternative to current state-of-the-art solid-state devices which have fundamental limits to the scaling potential hindering the way to cost-effective memories. SPS_Nano lays the foundation of colloidal data storage technology which can enable low-cost high-density memory by reducing the particle size and increasing the nanocapillary aspect ratios in the future.


**Keywords:** single particle tracking, dielectrophoresis, colloidal nanoparticle, optical trapping, data storage
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Preventing obesity through Biologically and bEhaviorally Tailored inTERventions for you - BETTER4U' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

BETTER4U aims at the identification and personalized management of all weight gain determinants to battle the increasingly rising numbers of overweight/obesity, via homogenous, globally adaptable and practically assessed public health initiatives and key interventions. Building on previous key projects and biobanks, the project will focus on the hitherto neglected impact of the polygenic background of weight gain on the effectiveness of lifestyle interventions for weight management in people with overweight/obesity. BETTER4U aims to probe into the global obesity challenge, study the problem and offer solutions in a tangible realistic way with the assistance of modern AI technologies and the contribution of experts around the world. BETTER4U will be realized through the following objectives: 1. To comprehensively understand and decipher genetics, metabolomics, microbiota, socio-economic, geographical, cultural and lifestyle features linked to weight gain throughout the life course, via meta-analyses (BETTER4U data from >50 studies, >1 million individuals) and extensive literature meta-review. 2.To develop the BETTER4U intervention methodology for weight gain prevention, based on a causal AI model of obesity determinants and a pilot study in 7 European countries. 3.To deploy technology-assisted, real-time monitoring tools to measure detailed behavioral indicators and their relation to the environmental context. 4.To evaluate the efficacy of the novel BETTER4U intervention methodology in a controlled, randomized clinical trial, based on individually-tailored recommendations for lifestyle change. 5.To maximize transferability and applicability of the BETTER4U intervention methodology by identifying implementation barriers and facilitators, as well as to evaluate implementat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Passive Actuated ventiLation Opening systeM for Aircraft' (PALOMA) under Horizon 2020.

assistant: **Objectives**

PALOMA will design and test a passively actuated opening system that will allow a volume of secondary air flow to be diverted into the engine core area for cooling purposes. Being entirely passive, no external electrical, hydraulic or pneumatic power will be required to run or control the system. The system will use a heat pipe to transfer the necessary heat to a shaped memory alloy (SMA) component whose movement will, through a set of mechanical linkages, open a flap set within the nacelle inner walls. This system will permit an optimisation of the engine thermal management and performance whilst needing minimal maintenance. Based on an agreed set of requirements, the project partners will first perform a trade-off in terms of possible heat pipe and SMA material and geometric forms, followed by their full characterisation. This information will permit a) the design of the system to be performed after a trade-off considering the constraints (positioning, extreme temperatures and aircraft accelerations) linked to the installation of such a system in a nacelle b) the modelling of the system’s behaviour. Having completed the design, a functional prototype will be tested on a specifically design test bench to simulate operation conditions including pressure, temperature and vibration according to the requirements of the DO160, mandatory for all equipment used on aircraft. The results of the tests performed on the functional prototype will be integrated into the design of a demonstrator (which may also be used for flight tests) which in turn will be manufactured and tested. Modelling activities will support the project throughout its execution. The PALOMA solution will be fully European and brings together: a thermal management engineering and modelling company, a heat pipe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Advanced 2D-material integrated photonics technologies for bio sensing' (NanoIP-BioS) targeting Horizon 2020.

assistant: **Abstract**

The key research goal of the project “Advanced 2D-material integrated photonics technologies for bio sensing (NanoIP-BioS)” is to enhance the leadership and research capability of the Marie Curie Fellow Dr Bing Sun, via implementing a highly challenging and innovative research project focused on the development of high sensitive and selective photonic biosensors by exploring two-dimensional (2D)-nanomaterial, i.e. graphene oxide (GO), black-phosphorus (BP) and MXene, and fibre microsensor structures for applications in food and water safety, environmental monitoring, and healthcare sectors. 2D-material have received significant attentions due to their unique mechanical, electronic, optical and chemical properties. Especially, black-phosphorus and MXene are a new family of 2D transition-metals that are analogous to graphene oxide. Because of their easy availability, hydrophilic behaviour, and tunable chemistry, graphene oxide, black-phosphorus and MXene have been recently explored for environmental pollution remediation such as heavy metal ions detection in water, soil, air and so on. This project will exploit new emerging opportunities with the integration of photonic technologies (fibre gratings, fibre tapers, photonic crystal fibres, fibre lasers) and advanced 2D-material (GO , MXene , BP ) to develop a range of new, highly sensitive, label-free, rapid and promising performance photonic biosensors to address EU and WHO raised issues in water and food safety and general public health care. The Fellow Dr Bing Sun from Nanjing University of Posts and Telecommunications (NUPT), China, will be trained in the fast growing photonics science, technology and application area at the host - Aston Institute of Photonic Technologies (AIPT, supervisor: Prof Lin Zhang, Female), Asto
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Species range shifts, aboveground-belowground community reassembly and consequences for ecosystem functioning' to be submitted under Seventh Framework.

assistant: **Abstract**

Climate warming promotes intra-continental range shifts of plants, animals and microbes from lower to higher latitudes and altitudes. Plants may shift their ranges independent of their co-evolved aboveground and belowground biota, however little is known about how these communities re-assemble in the new range and how that process influences community dynamics and ecosystem functioning. Thus far, predictions on species occurrences have been based exclusively on how niche conditions shift to higher latitudes and altitudes. Here, I will make the next step towards predicting how terrestrial systems respond to climate warming by evaluating interactions between plants, aboveground and belowground multi-trophic communities in the original and new ranges. My overall aim is to determine how aboveground and belowground multi-trophic level communities become disjointed and concomitantly re-assembled during plant range shifts. I will determine consequences for community dynamics and ecosystem functioning in the new range. My overall hypothesis is that due to time-lags in range shifts between plants, and their aboveground and belowground biota, novel communities may develop in the new range that will alter functioning of ecosystems, their stability and resilience. I will study range shifting plant species and determine: 1) aboveground-belowground multi-trophic community composition, 2) specificity of soil-borne pathogens and root-feeding nematodes, arbuscular mycorrhizal fungi, and decomposer organisms, 3) bottom-up and top-down control of these biota by soil communities, and 4) dynamics, stability and resilience of original and novel communities and ecosystem functions under current and future climate conditions. My results will be the first to show how the disjunction and reassem
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Trafficking to the Vacuoles in Plants' to be submitted under Seventh Framework.

assistant: **Abstract**

Occupying up to 90% of the volume of an individual cell, the vacuole is the most prominent compartment of the plant cell. The plant vacuoles are responsible for the transport and accumulation of nutrients, carbohydrates and storage proteins, and their function directly impacts plant yield and nutritional value. In plants, two types of vacuoles with different properties have been identified, the lytic vacuoles that carry out many of the same processes as yeast and mammalian lysosomes such as the breakdown and recycling of cellular components, and the protein storage vacuoles (PSVs) that carry out an additional number of plant-specific functions such as the accumulation and sequestration of toxic compounds and the storage of defense molecules such as alkaloids, phenolics, and protease inhibitors. Although components of the trafficking machinery to lytic vacuoles are well defined and appear to be conserved in yeast and multicellular eukaryotes, very little is known about the cellular machinery and regulatory mechanisms required for transport of vacuolar soluble proteins to the PSV. To define the genetic element and regulatory mechanisms required for the accumulation and mobilization of reserves into the storage vacuoles we will use a systems biology approach that combines computational tools (algorithm development), analytical tools (Proteomics), and a set of biological tools from the biochemistry, molecular biology and cell biology fields (Classical genetics, microscopy, and molecular biology) in the model plant Arabidopsis thaliana. The basic knowledge derived from this research will allow the design of experimental approaches aimed at improving biomass, production yield, and fitness through the enhancement of various vacuolar reserves in crops of economical interest.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Physics and Applications of Negative IONS' under Horizon Europe.

assistant: **Concept**

The structures of atoms and positive ions are well known for more than 100 years. In contrast, negative ions are less well understood as they are much more difficult to investigate and detect. This is because their binding energies are very small, and only a handful of them have excited states with the same parity as the ground state. Hence, traditional spectroscopic methods cannot be applied to most negative ions, leaving them poorly characterised despite their importance for many scientific and technological applications.The PANIONS Doctoral Network aims at substantially advancing our understanding of negative ions beyond the state-of-the-art from atomic to cosmic scales and bridging the gap between fundamental science and applications. Our interdisciplinary approach will be implemented by 14 DCs employing advanced theoretical models and sophisticated experimental methods. Key properties of atomic and molecular anions and their interactions with other particles will be investigated to fully describe negative ions in a variety of environments, from vacuum to plasmas, interstellar clouds and planetary surfaces. This ambitious research and training programme is only possible through a collaborative effort of a pan-European consortium of scientific excellence with access to a range of experimental facilities and the involvement of innovative companies with complementary expertise.Exploiting the full potential of the scientific discoveries requires a structured training programme to equip the next generation of experts in negative ions with advanced scientific and transferable skills. Acquiring a comprehensive skillset that is relevant to essentially any field of advanced science and technology, will prepare the recruited DCs for future careers in academia and industry. In