RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Sleep balancing abstraction and forgetting of memory'.

assistant: **Concept**

Sleep supports the formation of long-term memory, a function described as an active systems consolidation process. Concurrently, a long tradition of theorizing exists that sleep serves to forget unimportant memory. Paradoxically, the crucial behavioral demonstration that sleep induces forgetting is currently entirely missing. I hypothesize that memory processing during sleep is balanced: Sleep consolidates abstracted schema-like memory and this process is coupled to active forgetting of episodic detail. This twofold function of sleep is most prominently expressed, with a time delay, after learning large amounts of information exhausting the limited capacities of memory processing during sleep. It is particularly pronounced during development when due to a lack of preexisting knowledge, the brain faces conditions of permanent information overload.I will combine human and rodent studies to test the behavioral predictions of this hypothesis and to characterize the underlying neural mechanisms. Adopting the active systems consolidation framework, I target the following aims:1) to provide direct behavioral evidence that with high information load, sleep compared to wakefulness induces forgetting of episodic detail in favor of consolidating abstracted schema-like memory.2) to clarify how memory abstraction and forgetting are linked to slow wave sleep (SWS) and REM sleep, their characteristic EEG oscillations, and underlying forming and pruning of synapses. Specifically, I hypothesize that spindles support memory abstraction whereas slow oscillations, hippocampal ripples and REM theta concurrently contribute to both memory abstraction and forgetting. 3) to demonstrate enhanced sleep-dependent memory abstraction and forgetting during early development.This project by providing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Functional Genomics Analysis of Neisseria meningitidis interactions with human dermal blood vessels in vivo', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Neisseria meningitidis is still the major cause of bacterial meningitis and septicemia worldwide. The septic shock caused by Neisserial invasive disease is characterized by the presence of skin lesions (petecchial rashes and purpura). Despite the strong association of meningococcal disease and purpura as well as the serious prognosis associated with it, the bacterial factors and physiological processes underlying these events at molecular and cellular level are still largely undescribed.Here we propose to use a recently developed humanized-mouse model of meningococcal purpura to study by functional genomics (Transcriptome analysis and gene fitness analysis by High-throuput insertion track sequencing, HITS) the host-bacteria interactions during the process of vascular colonization by N.meningitidis in vivo. We expect that combination of these two approaches would highlight bacterial and host mechanisms important for vascular colonization. By the combination of cellular and biochemical approaches we expect to dissect these mechanisms and elicit bacterial determinants used to colonize and proliferate in human blood vessels and host molecular mechanisms that participates in causing vascular damage and purpura fulminans in response to bacterial infection. Understanding the details of vascular leakage may also give indications as to how N. meningitidis are able to cross the Blood Brain Barrier and cause meningitis.This experimental approach could have the potential to highlight suitable targets for future innovative meningococcal therapeutics and vaccines development. Futhermore, this project will give to the fellow the opportunity to learn scientific, technical and complementary skills, which could support his career development to become an independent researcher in the fie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The Medical Ecosystem - Personalized Event-based Surveillance' under Seventh Framework.

assistant: **Concept**

Many factors in today's changing societies contribute towards the continuous emergence of infectious diseases. Demographic change, globalization, bioterrorism, compounded with the resilient nature of viruses and diseases such as SARS and avian influenza have raised awareness for European society's increasing vulnerability.Traditional Epidemic Intelligence systems are designed to identify potential health threats, and rely upon data transmissions from laboratories or hospitals. They can be used to recognise long-term trends, but are limited in several ways. Threats, such as SARS, can go unrecognised since the signals indicating its existence may originate from sources other than the traditional ones. Second, a critical strategy for circumventing devastating public health events is early detection and early response. Conflictingly, the time with which information propagates through the traditional channels, can undermine time-sensitive strategies. Finally, traditional systems are well suited for recognising indicators for known diseases, but are not well designed for detecting those that are emerging. Faced with these limitations, traditional systems need to be complemented with additional approaches which are better targeted for the early detection of emerging threats.The Medical EcoSystem (M-Eco) project, will address these limitations by using Open Access Media and User Generated Content, as unofficial information sources for Epidemic Intelligence. This type of content has transformed the manner in which information propagates across the globe. Based on this, M-Eco will develop an Event-Based Epidemic Intelligence System which integrates unofficial and traditional sources for the early detection of emerging health threats. M-Eco will emphasize adaptivity and personaliz
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'High performance system for textile evaluation' to be submitted under Fourth Framework.

assistant: **Abstract**

The aim of the project is the design and realisation of an embedded parallel real-time system for the on-line quality control of finished textile products.The project has strong potential for impact in the textile-manufacturing process by addressing one of the most difficult tasks in the implementation of a fully automatic plant. It will customise a general-purpose software and hardware platform for quality control in the production of textiles. The system to be defined will be sufficiently generic to be applicable to other industrial sectors. The project makes extensive use of HPCN technology in order to achieve the performance needed in this real-time environment. A fundamental aspect of the industrial prototype will be its cost, significantly lower than that of existing systems and compatible with the requirements of industrial SMEs. It is estimated that the potential world market for such medium-sized systems lies between 500 and 1000 installations. It is expected that an even bigger market exists for scaled-down smaller systems.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'European Centre of Excellence for Engineering Applications on HPC and associated technplogies' (2021-2027) under Horizon Europe.

assistant: **Objectives**

EXCELLERAT P2 continues the fruitful partnership of Europe’s leading HPC centres, application specialists and supporting partners who have worked with and offered their expertise and knowledge to engineering companies and researchers from across industry and academia for the past three decades. A key strength of EXCELLERAT P2 is that it will build on the achievements of EXCELLERAT P1, including the available service portal  as a baseline for impact and awareness creation. Furthermore, the critical mass, knowledge and expertise of Europe is re-united and extended by additional experts, to continue the Centre of Excellence, which will span the whole domain of engineering – ensuring that innovations produced are applicable to other engineering challenges, that co-design is handled properly, that success stories are created and distributed, all in all to support best the European HPC strategy. EXCELLERAT P2 will base its evolution and developments on six chosen use cases, requiring the full range of HPC usage profiles, from small scale capacity type applications, all the way to hero run type large scale applications.The advancements the use cases as well as further applications will make beyond the state of the art, as well as the results, which will be derived by the execution of the use cases and the further applications, will have a clear impact in Europe. EXCELLERAT P2 (and the brand) strives to show the contribution of HPC, HPDA and AI in engineering to a low-carbon, more environmentally friendly and socially responsible product development and manufacturing as well as the mobility and energy sector.The holistic view of EXCELLERAT P2 to the usage of HPC (and HPDA and AI) is needed, if engineering applications shall be supported to increase the European competitiveness.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Exploring terra incognita: terrestrialization of arthropods in the era of genomics' under Horizon 2020.

assistant: **Concept**

Terrestrialization – the colonization of the land habitat by plants and animals – is amongst the most important events in the history of life on Earth. Understanding terrestrialization is, therefore, key to understanding biological adaptation. From all animals, arthropods constitute the most successful phylum, manifest in extreme species richness and successful radiation into nearly every ecological niche. Arthropods colonized the land multiple times independently and at different times in Earth history, with terrestrial arthropods massively outnumbering the aquatic ones. This begs the questions how, when, why and how often did arthropods become successful in the terrestrial environment, constituting ideal model systems to study terrestrial adaptations at the genomic, physiological and morphological levels. In order for animals living in aquatic environments to colonize land, a number of physiological barriers need to be overcome, including massive changes to methods of respiration, water management and osmoregulation, reproduction or digestion, among others. Water balance is one of the main challenges facing primarily terrestrial animals. Osmoregulation is also highly relevant to the question about the route taken onto land, specifically whether the ancestors of a given terrestrial arthropod group came directly from a marine environment or via fresh water. The main goal of this project is to shed light on the mode and tempo of these changes through the integration of phylogenomics, paleontology and comparative genomics and transcriptomics. For this, I propose to investigate i) the genetic basis of cuticular composition in marine and terrestrial arthropod lineages, ii) characterization of genes involved in osmoregulation, and iii) lineage-specific orphan gene families t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Proteomics 4D: The proteome in context'.

assistant: **Objectives**

Elements operating in the context of a system generate results that are different from the simple addition of the results of each element. This notion is one of the basic tenants of systems science. In systems biology/medicine complex (disease) phenotypes arise from multiple interacting factors, specifically proteins. Yet, the biochemical and mechanistic base of complex phenotypes remain elusive.An array of powerful genomic technologies including GWAS, WGS, transcriptomics, epigenetic analyses and proteomics have identified numerous factors that contribute to complex phenotypes. It can be expected that over the next few years, genetic factors contributing to specific complex phenotypes will be comprehensively identified, while their interactions will remain elusive. The project “Proteomics 4D: The proteome in context “explores the concept, that complex phenotypes arise from the perturbation of modules of interacting proteins and that these modules integrate seemingly independent genomic variants into a single biochemical response. We will develop and apply a generic technology to directly measure the composition, topology and structure of wild type and genetically perturbed protein modules and relate structural changes to their functional output.This will be achieved by a the integration of quantitative proteomic and phosphoproteomic technologies determining molecular phenotypes, and hybrid structural methods consisting of chemical cross-linking and mass spectrometry, cryoEM and computational data integration to probe structural perturbations. The project will focus initially on the structural and functional effects of cancer associated mutations in protein kinase modules and then generalize to study perturbed modules in any tissue and disease state. The  resources supp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Knowledge of the traffic loads and actions on steel orthotropic deck bridges and application for fatigue studies' (1994-1998).

assistant: **Innovation**

The main objectives of this proposed research contract are - to establish the effect of traffic loads on steel orthotropic bridge decks, - to identify axle and truck loads from measured strains, - to recalibrate and check conventional fatigue loads specified in Eurocode 1, Part 3 Traffic Loads on road Bridges", To facilitate the development of the Eurocode for Bridge Loading, considerable research was carried out in 1986-89 and 1990 l993 sponsored by the European Commission (DGXII and the European Community for Steel and Coal). Fatigue was considered in particular and the loading which should be specified to ensure safe designs of steel bridges derived. However, a fundamental problem with this research was the lack of combined load and response data, i.e., it was possible to monitors axle and gross vehicle weights on typical roads and to monitor strains induced in typical bridges but it was not possible to relate one to the other. The objective of this project is to monitor at the same time the traffic loads on orthotropic steel bridges and the strains induced by them. Training content (objective, benefit and expected impact) I have worked in the field of Bridge Weigh-in-Motion at Trinity College Dublin during his pre-doctoral studies and has gained considerable experience in this field. It would be of great benefit for him to follow this with training in an application of that technology. This will serve to broaden his perspective and to complement his existing experience with knowledge in a different but related field. Expertise in Steel Bridges is severely limited in Ireland and it will be of considerable benefit to be exposed to French expertise in this important form of construction. Links with industry / industrial relevance (22) While this project is not specific
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Green and sustainable chalcopyrite and kesterite nanocrystals for inorganic solar cells' to be submitted under Horizon 2020.

assistant: **Abstract**

Development of new efficient solar cells (SCs) is one of the hottest topics of the modern material science and technology. Among the challenges evoked by the progress in SC technologies is the quest for new efficient visible-light-absorbers that can be produced from Earth-abundant materials by eco-friendly methods. The aim of the project is to develop strategies for mild and ""green"" synthesis of ternary chalcopyrite ((Cu,Ag)InS(Se)2) and quaternary kesterite ((Cu,Ag)2ZnSn(S,Se)4) nanocrystals (NCs) as visible-light-sensitive active com¬ponents of the semiconductor NC-based solar cells. The principal idea is in realization of low-temperature (below 100 ºC) syntheses directly in polar solvents (water, dimethyl-sulfoxide, etc.) using non-volatile and low-toxic sulfur and selenium sources. Such syntheses will be realized in ambient conditions (no vacuum and inert atmosphere required) and on the gram-scale by using chalcogenide complexes of metals (Sn, In, Sb, etc.) as stabilizers imparting the NCs with the resistance to aggregation and ability to form self-assembled layers after the solvent evaporation. The synthetic protocols will be selected allowing for a precise control of the NC composition and size. The binary and ternary metal chalcogenide NCs will be tested as visible-light-sensitive components of prototype liquid-junction and solid-state SCs where the NCs will serve as spectral sensitizers of the wide-band-gap oxide AIIBVI-type photoanodes to enable photocurrent generation. For the NCs with the best photovoltaic properties synthetic protocols will be developed to produce concentrated colloidal ""inks"" ready for use in scalable technologies of the SCs fabrication.""


**Keywords:** colloidal synthesis, eco-friendly synthesis, optical properties, metal anion compl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Interdisciplinary research: Connecting complex plasmas with colloidal dispersions', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

This proposal represents the first concerted effort to study classical strongly coupled systems at the most fundamental individual-particle level, by using complementary approaches from different physics domains - complex plasmas and colloidal dispersions. These are complementary in many ways, the most important being that complex plasmas are virtually undamped at the particle timescales, whereas colloidal dispersions are overdamped and thus can be brought into equilibrium in a controlled way. Otherwise, both fields have similar advantages: Fully resolved 3D particle trajectories can easily be visualized, the pair interactions are tunable, and particles can be manipulated individually or collectively.The principal scientific aim is to study generic dynamical and self-organization processes at a detail not possible in the past. Scientific objectives include 1) particle dynamics of liquids, with the emphasis on mesoscopic processes in the supercooled state, e.g. dynamical heterogeneity, 2) phase transitions in solids, with particular attention on the evolutionary paths of crystal structure development and defect dynamics, 3) non-equilibrium phase transitions, with the focus on lane formation in driven binary systems and the dynamics at “atomistic” timescales, 4) phase separation in binary fluids, with the emphasis on the role of pair interactions in the demixing kinetics, as well as in the transition between spinodal decomposition and nucleation and growth regimes, 5) hydrodynamics at the discreteness limit, especially the onset and development of hydrodynamic instabilities at the particle scale, and 6) critical phenomena in particle systems with “designed” pair interactions, where the range and strength of attractive/repulsive parts can be tuned by external fields.