RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Heterogeneity and the Volatility of Financial Assets' in the context of a Seventh Framework call.

assistant: **Objectives**

The research objectives of the project consist in exploring a new, realistic and parsimonious framework for modeling heterogeneity in economics and in investigating its implications for analyzing the volatility of financial assets. First, in order to develop this framework, a novel approach in economics is proposed based on measure-valued stochastic processes, which are extensively employed in mathematical biology to study the heterogeneity of a population with respect to a genetic characteristic. The new modeling framework is extremely relevant in the current context of increasing interest in analyzing heterogeneity effects in economics and in studying the complexity of economic systems. Second, the new framework for heterogeneity is employed to develop a micro-founded stochastic volatility model. Since the resulting continuous-time model is expected to be non-affine and endogenous, it will address some of the limitations of the existing exogenous and affine stochastic volatility models. By its own nature, the research project has a strong inter-disciplinary character, being at the intersection between finance, economics, and mathematics. The proposed methodology for modeling heterogeneity in economics is based on infinite-dimensional mathematical objects. Therefore, understanding and applying such a methodology requires mastering advanced methods from functional analysis, a branch of mathematics that deals with infinite-dimensional spaces. The project will be implemented under the supervision of an expert with vast experience both in functional analysis and in quantitative finance and with an extensive research network in both fields. The training is concerned with both scientific and professional skills. The objectives of the scientific training consist mainly in ins
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'SYSTEM FOR EFFECTIVE ASSESSMENT OF DRIVER STATE AND VEHICLE CONTROL IN EMERGENCY SITUATIONS' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Based on available EU research results, SAVE will develop an integrated system to monitor the condition of drivers and undertake emergency handling prior to and during emergency situations (e.g. drunk-driving, fatigue). The system will allow for immediate detection of driver impairment and will follow a defined set of emergency control strategies that include a pre-emergency warning system for the driver and surrounding traffic and an Automatic Control Device which will safely drive the car to the roadside and stop it. The final system will extensively tested in trials with simulators and instrumented vehicles. The project will also provide guidelines and draft regulations on such emergency systems, widely exploiting and disseminating its results.The aim of this Project is to develop an integrated system (SAVE unit) that will in real time detect driver state and undertake Emergency handling, prior and during the Emergency situation. This will be realised by instant detection of driver impairment and hence shift of the car status to automatic driving mode, in order to effectively and safely control it. The work will be based on relevant research conducted in DETER, DREAM, GIDS, AUTOPOLIS and other DRIVE projects on driver status monitoring, excluding though as far as possible driver wiring" and authority information strategies. Also, the latest developments in PROMETHEUS CED 2-6 on automatic vehicle control are taken as the basis for this project.The work starts with analysis of drivers needs, expectancies and acceptance regarding Emergency support, in order to enhance public awareness of aids in this area. The analysis of the systems requirements of Emergency Systems and driver state monitoring will follow. The development phase begins with the realisation of detection
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Algorithms and experimental tools for integrating very large-scale single cell genomics data' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Robust and flexible tissue- and cell-type specific gene regulation is a definitive prerequisite for complex function in any multi-cellular organism. Modern genomics and epigenomics provide us with catalogues of gene regulatory elements and maps illustrating their activity in different tissues. Nevertheless, we are far from being able to explain emergence and maintenance of cellular states from such data, partly because we so far lacked characterization of individual molecular states and genome control mechanisms at their native resolution - the single cell. Recently, new approaches developed by the single cell genomics community, with several contributions from our group, allow massive acquisition of data on the transcriptional, epigenomic and chromosomal conformation states in large cohorts of single cells. In this research program, we aim to move forward rapidly to bridge a major gap between these experimental breakthroughs and models of genome regulation in complex tissues. We will develop algorithms and models for representing data the transcriptional profiles, DNA methylation landscapes and Hi-C maps of literally millions of cells. Our tools will be designed specifically to leverage on new single cell RNA-seq, single cell Hi-C, single cell capture-pBat and higher order 4C-seq that we will continue to develop experimentally. Furthermore, we shall enhance and optimize our interdisciplinary framework hand in hand with a working model aiming at unprecedentedly comprehensive single cell analysis of E8-E10 mouse embryos. This will provide us with hundreds of worked-out cases of tissue specific gene regulation. The techniques and insights from these studies will then be used to characterize cell type aberrations and epigenetic reprogramming in tumors. The open algorithms,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Gram positive Surface proteins in immune evasion' (SURFACE).

assistant: **Innovation**

The global incidence and rise of severe S. aureus infections accompanied by an alarming increase in antibiotic resistance warrants the development of novel treatment and vaccination strategies. This proposal combines the expertise of Dr. Nina van Sorge (Fellow) from the United States and the Prof. Jos van Strijp lab at the University Medical Center Utrecht in the Netherlands (Host institute). The Van Strijp lab is world leading in the identification and characterization of many secreted immune evasion molecules in S. aureus that prevent clearance of the bacterium even in the presence of vaccine induced opsonic antibodies. In other words, immune evasion molecules are vaccine evasion molecules. Dr. Van Sorge has unique expertise and knowledge on high-throughput assays, transposon library screening, whole bacterium assays and in vivo models relevant to the battle with S. aureus. Van Sorge in collaboration with the Van Strijp lab proposes a novel approach to identify suitable vaccine candidates by screening for surface-exposed S. aureus immune evasion molecules. The vaccine-induced antibodies directed against these proteins act as a double edged sword: they block the immune evasive properties of the bacterium by “inhibiting the inhibitor” and facilitate bacterial clearance through efficient opsonization and phagocytosis. The proposed research represents the first comprehensive study to identify S. aureus surface proteins with immune evasive properties, elucidate their mechanism of action and role in disease pathogenesis and evaluate them in a combination vaccine. The project at hand concerns a highly synergistic approach by which unique expertise, tools and knowledge becomes available to the European community.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Monitoring Of Oceanic inteRnal tIdes usiNG fibre optic telecommunication cables' (MOORING) under Horizon Europe.

assistant: **Objectives**

Ocean mixing plays a crucial role in the Earth’s climate as it balances the meridional overturning circulation that buffers global warming. Quantifying mixing is challenging because energy enters the ocean at basin-scale but it dissipates at cm-scale over the vast ocean. One common element in the cascade of energy towards small scales is the transfer of energy to internal waves, which ultimately drive ocean mixing. Energy transfers to the internal wave field are largely enhanced through flow interactions with topography. Observations of wave-topographic interactions are, however, scarce and its mechanistic understanding comes mainly from idealized process ocean studies, which lack a direct benchmark against nature. To fill the observational gap in ocean mixing, the MOORING project will explore wave-topographic interactions at unprecedented spatio-temporal resolution by combining novel submarine cable data with numerical advanced modelling. New data will be gathered using fibre-optic cables by means of a revolutionary technology, which has opened a new door for exploring bottom wave dynamics. The potential of these novel observations to identify ocean-mixing hotspots in the ocean remains, however, unknown. To shed light on this, I will gather conventional oceanographic measurements and integrate them in realistic high-resolution numerical simulations, leveraging my modelling skills. The MOORING project will bridge seismology and oceanography, integrating a variety of approaches, and it will allow me to be trained in observational methods at the hosting institution, while expanding my numerical skills in a secondment institution, fostering a network of national and international collaborators. The proposed approach could eventually be implemented at global scale with the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Libraries and Archives Collecting Newspaper Clippings Unified for Their Integration into Networks' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

In order to maintain their important position in the information market, clipping archives should be able to integrate their special skills (such as professional knowledge and experience in treating newspaper information) into the new technologies of the information society. LAURIN will carry out the preliminary work necessary for an efficient and smooth shift from the analogue" clipping archive to its "digital" successor. Therefore LAURIN work concentrates on two main areas:LAURIN will develop a generic model for the digitisation of newspaper clippings. A scanned image of the article as well as the full text will be prepared for storage and retrieval. An integrated thesaurus system will support librarians in indexing and handling the clippings.In addition to the local solution, LAURIN will set up a network, accessible via the Internet, of seven European libraries and archives collecting newspapers and clippings. It will guarantee that European citizens gain easy access to the index information as well as to the articles themselves. Only one search page will be needed, and users will be supported by several tools. The LAURIN network will be the pilot for a European network. The new service will benefit both libraries and archives, and enable European citizens to gain better and quicker access to all kinds of newspaper informationTechnical approachThe LAURIN architecture is based on:Local nodes, corresponding to local library systems, which organise clipping information into heterogeneous information bases, composed on relational databases, text bases and multimedia bases. Local nodes are provided with functionality for acquiring clipping information, for indexing, for querying the clipping base and for exporting summary data regarding clippings to the central node.A cen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Cavity quantum phonon dynamics' under Seventh Framework.

assistant: **Concept**

Large bodies usually follow the classical equations of motion. Deviations from this can be calledmacroscopic quantum behavior. These phenomena have been experimentally verified with cavity QuantumElectro Dynamics (QED), trapped ions, and superconducting Josephson junction systems. Recently, evidencewas obtained that also moving objects can display such behavior. These objects are micromechanicalresonators (MR), which can measure tens of microns in size and are hence quite macroscopic. The degree offreedom is their vibrations: phonons.I propose experimental research in order to push quantum mechanics closer to the classical world than everbefore. I will try find quantum behavior in the most classical objects, that is, slowly moving bodies. I will useMR's, accessed via electrical resonators. Part of it will be in analogy to the previously studied macroscopicsystems, but with photons replaced by phonons. The experiments are done in a cryogenic temperature mostlyin dilution refrigerator. The work will open up new perspectives on how nature works, and can havetechnological implications.The first basic setup is the coupling of MR to microwave cavity resonators. This is a direct analogy tooptomechanics, and can be called circuit optomechanics. The goals will be phonon state transfer via a cavitybus, construction of squeezed states and of phonon-cavity entanglement. The second setup is to boost theoptomechanical coupling with a Josephson junction system, and reach the single-phonon strong-coupling forthe first time. The third setup is the coupling of MR to a Josephson junction artificial atom. Here we willaccess the MR same way as the motion of a trapped ions is coupled to their internal transitions. In this setup,I am proposing to construct exotic quantum states of motion, and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Developing an European American NGS Network' (DEANN) targeting Seventh Framework.

assistant: **Abstract**

The DEANN project is a network formation initiative that involves six research institutions and universities from four EU countries and equivalently, six research entities from four Latin American countries. The overall goal is to strengthen research partnership among the participants by developing a shared scientific knowhow in the field of Next Generation Sequencing data analysis.  More specifically, the objectives are:(I) To reinforce the collaboration among partner organizations, both between EU and American partners and within EU partners, with the aim of developing long-term research partnerships.(II) To nurse the scientific excellence of the project participants in the field of NGS data analysis, with the aim of improving their position and competitiveness at the international level.(III) To elevate the critical mass and innovation skills of the consortium to act at the forefront of innovative proposals around the usage of NGS-based technologies addressing biomedical and biotechnology problems.(IV) To increase the competence of the project partners in applied genomics research with the aim of reaching translational opportunities in established and emerging economies.(V) To improve education, innovation and international orientation of PhD candidates and post-docs.The DEANN initiative achieves these objectives by creating a network of carefully chosen bioinformatics research labs and putting them to work together in an exchange, training and transference program that specifically serves the goals of the project. The consortium members collectively represent a diversity of expertise domains (Biomedicine, biotechnology and bioinformatics), strategic regional positioning, strong international presence, comprehensive training capability and long term projection.The DE
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Development of a 4D silicon detector for applications in nuclear, particle, and medical physics', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The PicoPix project will develop and deliver pixelated and radiation hard Low Gain Avalanche Detectors (LGAD) with sub 30-ps timing resolution for 4D particle tracking in high energy physics and imaging applications. Starting from AC-coupled LGADs, developed in the context of the RD50 collaboration, PicoPix will use novel techniques to redefine the state-of-the-art in LGAD fabrication: a) pixelation, with typical dimension in the order of few tens of μm; b) timing resolution, through thinner detectors; and c) radiation-hardness, through novel designs of the active detection volume. PicoPix will push the boundaries in many fields from fundamental science to industrial applications. The fellow, Dr Reynolds, an expert in hadron collider physics with broad experience in simulations, analysis techniques, and data interpretation, has experience in characterisation of silicon detectors. The supervisors, Dr Tricoli and Prof Nikolopoulos, have significant experience and leadership in detector instrumentation and physics analysis. The former leads the Brookhaven National Laboratory (BNL) Fast-Timing Silicon Sensor Test- ing Laboratory, and the latter played a key-role in the commissioning of the Irradiation Facility at the University of Birmingham (UoB). The hosts, UoB and BNL, have excellent facilities enabling PicoPix, including the BNL Silicon Fabrication Facility and the Birmingham Instrumentation Laboratory for Particle Physics and Applications (BILPA). The secondments and visits, including at Fermilab, DESY, and CERN, and collaboration with other academic fields and industries ensure PicoPix’s success and a unique environment for Dr Reynolds’ development.


**Keywords:** timing detectors, tracking detectors, semiconductor detectors, Low Gain Avalanche Detectors (LGADs)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'A disruptive multi-sensor chip for fast and effective management  of Sepsis at the point of Care' under Horizon 2020.

assistant: **Concept**

SepsiCare project, aims at developing a profitable and scalable business based on SepsiCare integrated biosensors. SepsiCare is an integrated biochip that is capable to provide a set of key patient-condition indicators to the clinician in order to diagnose sepsis, monitor disease progression and assess the effects of treatment within minutes. The SepsiCare device integrates multiple highly sensitive photonic sensors on a low cost 20x20 mm2 semiconductor chip that is configured to quantify a panel of sepsis related biomarkers from small volumes of patient whole blood. What differentiates SepsiCare from the competition is that it offers a multi-sensor test to quantify multiple parameters that indicate sepsis, identify bacteria and guide therapy with high accuracy (concentrations of pg/mL) and at an affordable price (12 Euro per chip). Sepsis affects more than 30 million people worldwide each year and takes 8 million lives including more than 3 million children, translating into healthcare yearly costs nearly $24 billion in the US alone. Starting appropriate and effective antimicrobial treatment is crucial for sepsis survival. Previous reports have shown that the chance of survival drops by 7.6% each hour of disease progression until an appropriate antimicrobial treatment is started. Therefore, achieving an early and accurate diagnosis is a prerequisite for rapid and successful antibiotic therapy. However, point of care (POC) solutions for fast, affordable and effective management of sepsis remains a challenge. The impact of this unmet clinical need to the hospitals relates to the increased time & cost of patient hospitalization (~€30K per sepsis patient). For patients, this has an impact on increased mortality and morbidity (1 in 3 patients of sepsis die) resulting from s