RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'KRAB zinc finger gene biology in evolution and disease' (KRAB-ZNF), addressing dissemination and exploitation.

assistant: **Impact**

The „KRAB-ZNF“ initiative is driven by recent observations that KRAB-ZNF genes, an evolutionarily conserved gene family of more than 350 transcriptional repressors encoded in the human genome, are predominantly expressed in testis and fetal brain. To elucidate functions of KRAB ZNF genes in evolution and diseases, experts in KRAB ZNF gene biology (B1/P1), proteomics (B1/P2), systems biology and aging (B2/P3), interspecies brain life histories (B3/P4), primate socioecology (B3/P5), human pathology (B3/P6) and in any aspect of computational biology (B4/P7-B6/P11) have established a well-coordinated interdisciplinary exchange program between German (B1,B2/P1-P3), Swiss (B3,P4-P6) and Chinese (B4/P7-B6/P11) institutions. Bioinformatic expertise encompasses network analysis (B4/P7 and B6/P10), molecular structure modeling (B5/P9), database design (B4/P8), and deep sequencing bioinformatics (B6/P11). Workpackages with defined topics are focused on the toponome analysis of KRAB ZNF protein expression (WP1), studying KRAB-ZNF interactions with TRIM28 (WP2), relating KRAB-ZNF gene functions to longevity (WP3), comparing brain sizes, fertility, cognitive behaviours and other aspects of life histories from birds to mammals (WP4), correlating SNPs of brain-related genes with social behaviour of e.g. primates (WP5), and on studying KRAB ZNF protein and related target proteins thereof in human pathology (WP6). The experimental data (B1/P1-B3/P6) will be analyzed in conjunction with experts in bioinformatics (B4/P7-B6/P11), compared to existing world-wide-knowledge (WP7), upon perturbation by small molecules (WP8), modeled upon protein interaction data (WP9), assembled in comprehensive databases (WP10), and finally analyzed phylogenomically (WP11). Within the requested funding period
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'POPULATION DYNAMICS OF MEDITERRANEAN WATERBIRDS AND THEIR DEMOGRAPHIC AND BEHAVIOURAL RESPONSES TO GLOBAL CHANGE' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Coastal, wetland, island and marine ecosystems have been largely modified during the last century making them especially vulnerable to global change threats. In the Mediterranean basin over the last few decades, major socio-economic changes have increased the negative impact of human activity, mainly along the coasts, pushing many endemic species on the edge of extinction. The ability of populations to respond to environmental changes, and their speed, will depend on the existence of individual behavioural variability. The study of the relation between individual behaviours in response to environmental conditions (climatic factors, biotic relations and derived from socio-economic activities) and their demographic consequences, establish a key framework to investigate the role of present threats and of the future scenarios previsions on the dynamics and conservation of potentially vulnerable species. The present project aims to study the demographic and spatio-temporal population dynamics consequences of different individual life-history tactics in response to global change threats of three Mediterranean waterbirds: the Greater flamingo , the Audouin’s gull and the Cory’s shearwater. This proposal establishes a combination of state of the art modelling techniques, statistical tools and behavioural and individual-based information. This will imply estimating the individual behavioural responses to environmental conditions, their demographic parameters and applying matrix population models to explore the consequences of such behaviours. The project will be developed in a top European research centre – CEFE-CNRS, France – which provides highly expert background in complex statistical analysis and advanced modelling techniques. The project will count on the collaboration of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Communication Development in Infants: the Case of the Hadza Hunter-Gatherers of Tanzania' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The way children learn to communicate verbally and non-verbally depends to a great extent to the culture in which they are raised. Much is known about the social environment of children living in Western societies, but much less is known about how children are socialized in hunter-gatherer societies. The proposed project aims at gaining insights into the development of communication in hunter-gatherer children. The project’s aims are • to develop a minimally intrusive assessment method that gives access to the learning process by including physiological measures.• to analyze physiological responses to infants’ verbal and non-verbal interactions with their social environment focusing on the Hadza, as a particularly interesting cultural community. • extract patterns in data from diverse sources (audio, video, observation, electrophysiological measures) with automated data mining methods.The approach is interdisciplinary, integrating methods from anthropology and ethology with modern physiological assessment methods, innovative wearable technology and data mining techniques. It is important to know more about the development of communication in Hadza infants as communication in hunter-gatherers has not been comprehensively studied and the Hadza are a community living in conditions that resemble our ancestors’ living conditions. This helps to shed light on the evolution of language in our species. As hunter-gatherer societies are increasingly threatened due to ecological, economic and political changes in their environment, it is crucial to conduct this research as soon as possible.My personal training targets are to apply my previous field work experience to a new and interesting cultural community and relate this to theories about the evolution of language, to fruitfully
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Manufacture of finished articles and textiles from adjustable highperformance attributed, polypropene resin based yarns' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Development and application of catalyst systems of high efficiency deliver polymers which are characterised by their MFR value being in the range of 10-40 g/10min. Elaboration of extrusion conditions in relation to properties of applied polymers in order to achieve improved productivity and yarn characteristics allows recommendations for the main settings. This knowledge will be a tool for every producer in order to adapt the processing of the new products to their production lines.By investigation of yarn processing by the institutes, an indication of the range of settings for drawing, texturisation or staple processes is given, which meet the specific polymer needs and foreseen end uses, e.g. as apparel, home, technical or automotive textiles. This has been the basis for transfer and adaptation into industrial production at SMEs. However, regarding the respective results of industrial yarn, textile and carpet production, the achievable quality was not as good as expected and only could be reached with one type of polymer type, so that there is only a limited added value to be foreseen when applying this polymer to production. For some special processes (coarse technical yarn) it was not possible to reach standard quality.This project aims to demonstrate on principle how to produce industrially textile articles, like fabrics and carpets, of better perfommance by processing yarns on existing machinery exhibiting improved properties with respect to tenacity, resilience, abrasion resistance etc. The yarns will be based upon new types of polypropene, which are going to be manufactured by the use of metallocene catalysts. In addition to offering higher quality products made from these materials it is intended to increase productivity by means of producing at higher speeds.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Application of technology watch methodology for assessment of regional-innovation-policy impact on SMEs' to be submitted under Sixth Framework.

assistant: **Abstract**

The INNOWATCH project is intended to develop a tool that allows the assessment of the efficiency and responsiveness of regional innovation policies, both past and on-going, based on technology watch methodologies and specifically oriented towards innovati on impact in SMEs. The final objective is to integrate this tool into the mainstream regional policy-making processes, therefore facilitating the definition of policy guidelines and allowing more effective allocation of public resources. Within this propo sal the assessment tool will be first developed and afterwards implemented in the four partner regions -Comunidad de Madrid (Spain), Sicilia (Italy), Ile-de-France (France) and Poladskie (Poland)-, and a benchmarking analysis based on the regional results obtained will be performed. As an effect of the benchmarking analysis, specific recommendations for regional policies will be performed on the basis of the identified successful actions, regional idiosyncrasies and regional Sustainable Development.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Detection of presence of species-specific processed animal proteins in animal feed SAFEED-PAP (SAfe FEED - Processed Animal Proteins)', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

Title : Detection of presence of species-specific processed animal proteins in animal feed (SAfe FEED Processed Animal Proteins) Acronym : SAFEED-PAP Since the earliest case of the bovine spongiform encephalopathy (BSE) epidemic was first confirmed in t he United Kingdom in 1987, strict legislation was set up year after year.This has been done taking into account new scientific and epidemiologic evidences showing that meat and bone meal are the most probable vector of the disease, in order to eradicate B SE in Europe. Nowadays, the European Commission has come to the stage that amendments of certain measures could be envisaged, without endangering the health or the policy of eradicating BSE, provided that the positive trend continues and scientific conditions are in place.The scientific conditions to complete regarding the amendments of the total feed ban are the development and validation of analytical methods and tools for the detection of the presence of species-specific animal proteins in animal feed. Actually, the existing methods do not allow species-specific identification and lead to the impossibility to lift the total ban and to implement the anti-cannibalism ban. SAFEED-PAP aims to complete the scientific conditions that should allow the repealing of the extended feed ban.SAFEED-PAP will use the inherent difference and complementarities of the various methods in terms of their targets to develop and validate methods that will allow reaching the scientific conditions for the amendment of the total feed ban. SAFEED-PAP has three main objectives:- Development of suitable validated methods for the species specific detection and quantification of animal protein in compound feed in order to allow the amendment of the extended total band;- Development of tools and an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Volumental - The Cloud-Delivered 3D Scanning Service Supporting A Future Of Mass Customization'.

assistant: **Objectives**

Volumental is currently building, and delivering, leading software technology that enables the 3D scanning of objects, (e.g. bodies), using both current and emerging camera technologies. The resulting accurate scans can be readily used by mainstream 3D software systems & packages.Volumental is currently focusing on the mass customization market, even though Volumental technology itself is broadly applicable. We sell software solutions B2B to e.g. footwear brands that can use 3D body data to customize e.g. shoes to the multibillion footwear market. We have a number of partners and pilot customers in this field already, among them US footwear brands and the worlds largest hardware manufacturers in our field.Enabling technology development of mass customization in Europe offers the opportunity to move production products that touch the human body back to European markets as well as building technology leadership within fields such as 3D scanning and 3D printing.The key differentiator for Volumental is that our proprietary software algorithms can produce high-accuracy 3D models using inexpensive hardware. Further on we excel in ease of use, having a cloud service and have a sustainable competitive advantage in the technology leadership our team has shown and continue to show.For the Horizon 2020 project Volumental’s high-level goal is to turn our technology and prototypes into fully functional products in their final end-user configuration. This translates to taking the products to TLR 8. This will require significant R&D to achieve – mainly focused at improving robustness, free-hand accuracy, mobile phone scanning and API development. This R&D will result in additional inventions, so the project also aims to protect current and resulting inventions by analysing the current
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Research and development of tribological coatings with tailored desorption properties' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Novel smart" tribological coatings with tailored out-gassing properties will be developed for using in intelligent vacuum machinery of new generation. The peculiar property of the "smart" tribological coatings is that, in addition to good tribological performance, they have given gas desorption behaviour controlled by destructive processes, i.e. fracture, plastic deformation, wear, etc. The coatings should be tailored in such a way that they will be able to send "desorption message" when some failure of the coating has happened.To achieve the aim of the project the following stages have been identified:(1) survey and analysis of existing tribological coating in relevance to vacuum applications,(2) experimental research of the tribodesorption behaviour fo r the wide range of materials in order to achieve fundamental understanding of the phenomenon,(3) modelling of tribodesorption and(4) development of the coatings.The later stage includes development of the structure and chemical composition of the coating, selection of appropriate deposition techniques, etc. providing given out-gassing properties and behaviour of the tribologocal coatings."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'TeraHertz detection enabled by mOleculaR optomechanics' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The generation, manipulation and detection of electromagnetic waves across the entire frequency spectrum is the cornerstone of modern technologies, underpinning wide disciplines across sensing, imaging, spectroscopy and data processing, amongst others. Whilst the last century has witnessed an impressive evolution in devices operating at frequencies either below 0.1 THz (microwave and antenna technology) or above 50 THz (near-infrared and visible optical technology), in between the lack of suitable materials and structures for efficient electromagnetic manipulation has resulted in the so-called “THz gap” : a band of frequencies in the 0.3 – 30 THz region of the spectrum for which compact and cost-effective sources and detectors do not exist – even though their application has enormous potential in medical diagnostics, security, astronomy, and wireless communication.In this project, we will demonstrate the first nano-scale, cost-effective, fast and low-noise detector working at room temperature in the 1 – 30 THz range by developing a radically new concept of signal up-conversion to visible/near-infrared (VIS/NIR) radiation, leveraging the latest scientific breakthroughs in the new scientific field of molecular cavity optomechanics. In particular, we will design and synthesize molecules with both large IR and Raman vibrational activity in that THz range to be integrated into plasmonic nano- and pico-cavities so that their vibration mediates the coherent transfer of energy from the THz to the laser signal driving the cavity. In our approach, we will also employ THz antennas to improve the coupling efficiency of the THz field to the molecules. This bold vision, which builds on the fundamentals of light-matter interaction (science) and converges toward the on-chip integration
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Polycomb in development, genome regulation and cancer' to be submitted under Seventh Framework.

assistant: **Abstract**

Polycomb group (PcG) and trithorax group (trxG) genes were discovered in Drosophila melanogaster as repressors and activators of Hox genes, a set of transcription factors that specify the antero-posterior axis of the body plan. PcG and trxG proteins form multimeric complexes that are required to maintain their expression state after the initial transcriptional regulators disappear from the embryo. Subsequent work led to a better understanding of their mechanisms of action. Moreover, PcG and trxG genes have also been identified in vertebrates, where they regulate Hox genes, they are involved in cell proliferation, stem cell identity and cancer, genomic imprinting in plants and mammals and X inactivation. PcG and trxG components form multimeric complexes. Some trxG and PcG components possess methyltransferase activities directed toward specific lysines of histone H3, whereas other trxG and PcG proteins interpret these histone marks. Recent studies have described the genomewide distribution of PcG proteins and of their related histone modification in Drosophila and other species. However, the PcG recruitment code to their target chromatin is still not understood, and the mechanism of PcG-mediated gene silencing is unclear. The formation of subnuclear silencing compartments might contribute to the stable repression of transcription. Drosophila PcG proteins have a speckled nuclear distribution and the number of these so-called PcG bodies is progressively reduced during development. We showed that multiple PREs can associate in the nucleus to enhance the strength of PcG-mediated silencing. However, we do not know how frequent is this clustering process and how important it is functionally at a genomewide level. Our project will tackle these questions by using a combination of