RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Multimodal Analysis of Human Nonverbal Behaviour in Real-World Settings' (MAHNOB), addressing dissemination and exploitation.

assistant: **Impact**

Existing tools for human interactive behaviour analysis typically handle only deliberately displayed, exaggerated expressions. As they are usually trained only on series of such exaggerated expressions, they lack models of human expressive behaviour found in real-world settings and cannot handle subtle changes in audiovisual expressions typical for such spontaneous behaviour. The main aim of MAHNOB project is to address this problem and to attempt to build automated tools for machine understanding of human interactive behaviour in naturalistic contexts. MAHNOB technology will represent a set of audiovisual spatiotemporal methods for automatic analysis of human spontaneous (as opposed to posed and exaggerated) patterns of behavioural cues including head pose, facial expression, visual focus of attention, hands and body movements, and vocal outbursts like laughter and yawns. As a proof of concept, MAHNOB technology will be developed for two specific application areas: automatic analysis of mental states like fatigue and confusion in Human-Computer Interaction contexts and non-obtrusive deception detection in standard interview settings. A team of 5 Research Assistants (RAs), led by the PI and having the background in signal processing and machine learning will develop MAHNOB technology. The expected result after 5 years is MAHNOB technology with the following capabilities: - analysis of human behaviour from facial expressions, hand and body movements, gaze, and non-linguistic vocalizations like speech rate and laughter; - interpretation of user behaviour with respect to mental states, social signals, dialogue dynamics, and deceit/veracity; - near real-time, robust, and adaptive processing by means of incremental processing, robust observation models, and learning person-s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'ADVanced communicAtions and iNformaTion processing in smArt Grid systEms' (ADVANTAGE) targeting Seventh Framework.

assistant: **Abstract**

Smart Grid systems represent a significant new technology to provide more energy efficient power delivery systems that reduce carbon emissions and can handle a mix of energy sources from small scale renewable energy to large power stations. The design and implementation of the smart grid will be very complex, involving a large number of systems, layers and relationships. In order to make the infrastructure of smart grid systems work effectively, engineers need to be trained to have a detailed understanding of both power engineering and communications issues. Many related research projects to date involve either mainly power engineers or mainly communications/signal processing researchers, limiting the interaction and knowledge exchange between these two communities. However, smart grid engineers should be able to appreciate the power network that the smart grid is designed for and how to communicate and process data concerning the power grid, so that it can be controlled effectively. This ITN project is a major interdisciplinary project between both power and communications engineers to train the next generation of engineers and scientists that will lead the development of this technology both within Europe and Internationally.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Communications for eSafety2' under Seventh Framework.

assistant: **Concept**

PREFACE: This DoW for COMeSafety2 represents the third version since start of project. This update was necessary for various reasons:- delay of deliverables due to lack of resources or unavailable   information- update of deliverables due to findings and recommendations of the 1st and 2nd Annual Review- re-alignment of goals and objectives of project and corresponding re-allocation of budget to partners.<br/>According to the recommendations of the 1st Annual Review in Q2/12 this DoW was updated in December 2012. Following the recommendations of the 2nd Annual Review in Q2/13 the project will be extended (by 3 month) until end of Q1/2014. This extension, in particular for the work packages WP2 and WP3 is used to integrate latest results regarding deployment of C-ITS and to update/ complete deliverables.<br/>The COMeSafety2 project proposal aims at the coordination of the activities towards the realisation of cooperative systems on European roads. The project will support and coordinate the development of the necessary standards under the ITS standardisation mandate at ETSI and CEN. It will support the mutual validation and exploitation of programme results under the EU-US cooperation agreement by active participation in task forces and organisation of workshops. The project will push the finalisation and implementation of the European ITS Communications Architecture, taking up from the COMeSafety Support Action in FP6. The project will target international and especially intercontinental synergies of FOTs. The project will provide a platform to bring together all stakeholders to agree on technical solutions and will aim at roadmaps that will offer ways how to realize and implement research results in a developing real-world cooperative system environment. It will support
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Development of small molecule OGG1 Inhibitor and proof of concept in bleomycin-induced disease model of Inflammation and pulmonary Fibrosis' (DOIIF) targeting Horizon 2020.

assistant: **Abstract**

Fibrosis in response to tissue damage or persistent inflammation is a pathological hallmark of many chronic degenerative diseases whereIdiopathic Pulmonary Fibrosis (IPF) is one of the most severe diseases. IPF is a progressive condition with unknown etiology and a mediansurvival of three years from diagnosis. Current medical treatment is limited to slowing down the disease and thus there is still a high unmet medical need. OGG1 enzyme has a major role in DNA repair in conditions of oxidative stress and also in regulation of gene transcription involved in immune responses. In our ERC grant we developed a first-in class OGG1 inhibitor that protects from exaggerated immune response induced by the proinflammatory mediator TNFα. We have shown with this compound inseveral airway inflammation models, that inhibition of OGG1 results in a significant down regulation of mediators associated with inflammation and fibrosis, reduced infiltration of immune cells in lungs and increased alveolar integrity compared with control. We have developed a large number of compounds and in this proposal we aim to demonstrate proof of concept (PoC) for the most promising compound in an established model of pulmonary fibrotic diseases in order to select a candidate drug (CD). Our plan is to establish collaboration with industrial partners for further development in order take one compound through preclinical development and clinical phase 1/2a for further commercialization. Treatment with a potent OGG1 inhibitor has the potential to attenuate or resolve the progress of the disease, alone or in combination with existing therapies and increase survival of IPF patients and reduce healthcare costs.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'DHaptics: Creating silent and sharp Mid-air Haptics using phased array of ultrasound transducers' (DHaptics) under Horizon 2020.

assistant: **Objectives**

A fundamental shift is underway in how we interact with our computers and devices. Products such as Microsoft’s Kinect and Leap Motion’s desktop controller enable us to dispose of the keyboard and mouse and instead control our devices without touching them. Touchless sensing products are being launched across the consumer electronics, automotive and healthcare industries. A significant and well noted problem with touchless sensing is a lack of tactile feedback.The PI and his team are the first in the world to create a novel haptic feedback system that allows users to feel tactile sensations in bare hand while interacting in mid-air with a system. This is likely to be a huge commercial success provided we can make some improvements to the distinct audible hum that is generated by our system.This project will realize a proof of concept phased-array haptic system that is silent and sharp.  Our prototype will enable two advantages over the existing haptic system. a) Elimination of audible noise when creating a single and multiple tactile pointsb) Maintaining perceptual sharpness of the tactile focal point while eliminating the audible sound
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'ERA-NET on Solar Electricity for the Implementation of the Solar Europe Industry Initiative' under Seventh Framework.

assistant: **Concept**

The goal of SOLAR-ERA.NET is to undertake joint strategic planning, programming and activities for RTD and innovation in the area of solar electricity generation, i.e. photovoltaics (PV) and concentrating solar power (CSP). Joint activities, namely joint calls, are defined for key topics and priorities in accordance with the Solar Europe Industrial Initiative (SEII) based on the Strategic Energy Technology (SET) Plan and its related Implementation Plans for PV and CSP.The network's activities will primarily involve the launching of joint calls for RTD proposals by national and regional RTD and innovation programmes. In order to define and support best joint activities, strategic information exchange and use of implementation tools will be carried out among the network participants and associates from key stakeholder groups.As the largest European network ever - with 19 partners from 18 countries and regions - in the solar power field, SOLAR-ERA.NET will involve more than 20 RTD and innovation programmes dealing with PV and CSP. This high level of involvement of most relevant stakeholders will provide excellent outreach and coordination needed for an efficient and coherent approach in the highly diverse and versatile RTD landscape.The EC funding (for the ERA-NET project) shall be multiplied by a factor of 50 in the form of joint calls. These joint calls for RTD and innovation topics in PV and CSP shall result in a total funding volume by the participating programmes of at least 50 MEUR. Assuming an average leverage factor of associated funding by industry and research of 2,5, this shall lead to the mobilisation of at least 125 MEUR in joint projects.SOLAR-ERA.NET will thus contribute to reach the objectives of the SEII, namely boosting the development of the PV and CSP s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Advanced Surface Enhanced Raman Spectroscopy (SERS) based technologies for gas and liquids sensING in the area of chemical protection' (SERS) under Horizon 2020.

assistant: **Objectives**

The ultimate goal of SERSing is to enable fast detection and unequivocal identification of chemical hazards at low concentrations in gas and liquid phase, in multiple environments. The geo-located acquired data are submitted to an on-line learning platform and processed, transmitting threats and hazard data to authorized personnel and generating alerts on the incident scene in real time. The innovative microdevices for detection and identification are integrated in low weight hand-held Raman equipment, specifically customized to overcome the common operational limitations of first responders, compatible with Personnel Protective Equipment PPE and respirators, easy to use and maintain with low cost of consumables. The robust, reliable, ultrasensitive lab on chips (LoCs) for on-site detection of chemical threats in gas and liquids are based on Surface Enhanced Raman Spectroscopy (SERS). The customized Raman spectrometer will combine geo-location and communication technologies specifically adapted for the rapid screening of the incident scene. This miniaturized platform could be also mounted on robotic units to inform operational command on possible chemical agents in preparation of entering the incident scene where the deployment of personnel is difficult.These SERS LoCs and the adapted Raman are also envisioned as complimentary forensics tools and technologies that can be used: i) “on scene” to determine the chemical nature of a sample in order to collect it for further laboratory analysis or dismiss it; or ii) “in a laboratory environment” for profiling chemical agents released at an incident and to identify signatures for improved attribution.


**Keywords:** surface enhanced raman spectroscopy, chemical threats, first responders
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Structural characterization of a Kir potassium channel and its involvement in Andersen’s syndrome'.

assistant: **Concept**

The inward rectifier potassium (Kir) channels belong to a family of integral membrane proteins that selectively control the K+ ion permeation in cell membranes. They are ubiquitously expressed throughout the human body and regulate the membrane electrical excitability and K+ transport in many cell types. The gating of Kir channels is modulated by various intracellular ligands, with phosphatidylinositol-4,5-bisphosphate (PIP2) being an essential molecule to Kir channel activity in eukaryotes. The physiological importance of the Kir channels is highlighted by the fact that genetically-inherited defects in the Kir channels are responsible for a number of human diseases, such as Andersens syndrome (AS), Bartters syndrome, and neonatal diabetes, which are often chronically debilitating and for which there are no efficient therapeutic treatments. This project goals to obtain high-resolution structures of the human Kir2.1 channel wild type (WT) and an AS-causing mutant (R312H) located at interaction site of PIP2, in the presence and absence of PIP2 as well as the description of the molecular mechanisms allowing gating of the channels in the WT and mutated forms with/without PIP2 using advanced molecular dynamics simulations techniques. For this, this project proposes the integration of cryo-microscopy (cryo-EM) combined with image analysis (single particle analysis or 2D crystallography) with a recently developed molecular dynamics simulations approach (MDeNM), which is a powerful tool to structurally characterize functional motions occurring over long time scales. The description of full gating mechanism of human Kir2.1 channel and the PIP2 role on its dynamics, as well as the understanding of the clinically-relevant disease-causing mutation impact on the structure, dynamics,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Stairway to AI: Ease the Engagement of Low-Tech users to the AI-on-Demand platform through AI' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The most fundamental need of the AI4EU on-demand Platform at this stage in its development is the introduction of improved functionality to allow for the easy engagements of it core targets stakeholders, namely SMEs. While additional resources and strong domain-specific solutions are also needed, it will be a wasted enterprise without a simple mechanism to match users to these assets. What is needed is a Stairway to AI, a linking bridge between users in a low-tech level to the higher-level AI resources that have the potential to transform both their business.The StairwAI project targets low-tech users with the goal of facilitating their engagement on the AI on-demand Platform. This will be achieved through a new service layer enriching the functionalities of the on-demand platform and containing: (1) a multi-lingual interaction layer enabling conversations with the Platform in the user’s own language, (2) a horizontal matchmaking service for the automatic discovery of AI assets (tools, data sets, AI experts, consultants, papers, courses etc.) meeting the user business needs and, (3) a vertical matchmaking service that will dimension and provision hardware resources through a proper hardware provider (HPC, Cloud and Edge infrastructures).These services are designed and implemented by using techniques in an AI for AI fashion. The AI techniques deployed in the development of the services are natural language processing for the multi-lingual interaction, constraint solving, optimization and machine learning for horizontal and vertical matchmaking, knowledge representation for organizing the platform AI assets, reputation and fairness mechanisms to improve the matching results. StairwAI will have a tremendous impact on the sustainability, collaboration opportunities, accessi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Closed-Loop and multisEnsing delIvery tool for controlled Laser Ablation of tumors' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

The need of a minimally invasive alternative to traditional cancer surgery is pushing the global market of thermal ablation devices, mainly for treating delicate organs (brain, prostate, breast, pancreas, lung) in inoperable patients. With its fine and flexible applicator, laser ablation (LA) was successfully used in lesions difficult to access with conventional surgery, and its market is expected to show the highest growth rates in the next 5 years. However, crucial aspects and clinical needs are still unsolved for LA: the poor reproducibility of the procedure outcome and the lack of mini-invasive and accurate intraprocedural control make LA strongly relying on the doctor experience. The lack of control causes subtotal tumor coverage, thus bringing cancer progression and recurrence. To solve this issue, in the ERC LASER OPTIMAL project that I lead, it was developed the first platform which integrates a closed-loop control strategy of LA with multiplexed fiber optic sensors (FOSs) at the millimetric-scale, and modulates the laser power based on the measured tissue temperature. LEILA is the integration of this control platform with a novel smart applicator embedding the laser delivery and the temperature monitoring with FOSs. In this PoC proposal, the technical-commercial feasibility study will be performed to move the LEILA system to the market. The PoC will allow prototyping the system, establishing contact with stakeholders for testing and integration of LEILA in existing medical systems, and preparing a ready-to-use tool. The PoC will also set the market and health technology assessment, the business model, and the IP protection strategy with identification of the best exploitation strategy for valorising the know-how.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Light4Switch: Conformational Switch of Light-Harvesting Complexes Upon Illuminating Azobenzene' (Light4Switch) under Horizon Europe.

assistant: **Objectives**

Plants can dissipate excess absorbed light energy as heat, by reversible switching of light-harvesting complex II (LHCII) into photoprotected quenched states, to prevent photodamage of photosynthetic apparatus. The conformational switch of LHCII is suggested to modulate the interaction between the embedded pigments, and consequently activate charge transfer and/or excitation energy transfer processes which ultimately lead to the dissipation of excess energy as heat, known as energy-dependent quenching (qE).  Although the site of qE has been long established, i.e. the LHCII, the specific protein domains and conformational switches responsible for activating qE are currently unknown.This MSCA fellowship project AZO-LHCII aims to determine the role of the protein matrix of the LHCII in tuning their energetic state and driving the photoprotective switch of plants. To this end, this disciplinary project will for the first time strive to manipulate the conformation of LHCII antenna proteins with azobenzene photoswitches and use a novel multipulse transient absorption spectroscopy approach to study in real-time the effect of site-specific conformational fluctuations on the regulation of the excitation energy transfer in LHCII.


**Keywords:** Azobenzene, Ligh-harvesting complex, Transient absorption spectroscopy, Energy transfer