RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Climate Advanced Forecasting of sub-seasonal Extremes' (CAFE) under Horizon 2020.

assistant: **Objectives**

Climate extremes such as heat waves or tropical storms have huge social and economic impact. The forecasting of such extreme events at the sub-seasonal time scale (from 10 days to 3 months) is challenging. Since the atmosphere and the ocean are coupled systems of enormous complexity, in order to advance sub-seasonal predictability of extreme events, it is crucial to train a new kind of interdisciplinary top-level researchers. CAFE research is structured in three WP: Atmospheric and oceanic processes, Extreme events and Tools for predictability, and brings together an interdisciplinary team of scientists. Objectives: Study of the relation between RWPs and the large scale environment, and the resulting limit of predictability; Statistical characterization of MJO events, dependence on climatic factors, and simple modelling to evaluate predictability; Development of diagnosis tools for identification and tracking of the MJO, blocking, waves and oceanic structures; Analysis of climatic changes in weather patterns and their relation with new climatic phenomena and extreme events in Europe; Estimation of probabilities for severe damages due to extreme events associated to ENSO; Validation of the hypothesis of cascades of extreme events and effects of a non-stationary climate; Estimation of exceedance probabilities for intensity of severe atmospheric events, including windstorms and hurricanes; Assessment of the response of extreme weather events for different levels of stabilized global warming and comparison with their response to internal modes of climate variability; Development of a procedure to improve the predictability of the onset of monsoon; Advanced statistical analysis of dynamic associations between SSS and extreme precipitation events; Study of predictability of l
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Inventory and analysis of biotech programmes and related activities in all countries participating in the biotechnology programme 1994-1998 -part 2'.

assistant: **Innovation**

This proposal is linked with three related projects (parts 1, 3 and 4 of the same title) which, taken as a whole, have the main objective to produce an exhaustive inventory, analysis and overview of biotechnology research, technology and development (RTD) in EU and EFTA/EEA countries directly stimulated by specific public programmes. The project covers: (a) each Member State which participated in the Biotechnology Programme 1994-1998; (b) the most important topics in biotech research, including the priority topics of theBiotechnology Programme 1994-1998; (c) making an overview of a range of factors connected to the conditions, policies and impacts etc. of these public programmes; (d) and producing on the basis of this overview analyses, conclusions and recommendations .  In deciding on specific topics and factors to be included in (b) and (c), we will be guided by a Steering Group including officials from the EC responsible for this study and a selection of governmental representatives and scientists which function as contact people in the EU and EFTA/EEA member states for the Biotechnology Programme 1994-1998. We will combine (b) and (c) in a matrix (biotech topics versus factors) for each Member State in (a). After the information and data on programmes concerning R&D and related activities for each country are collected and put in the matrix, an analysis will be made to provide an overview of biotech RTD in countries participating in the Biotechnology Programme, including the extent of co-ordination between European and national biotech programmes and related activities The purpose of this specific proposal will be to gather and analyse data on Germany, Austria, Italy, Belgium, Finland and Switzerland using the common framework which we shall develop in liaison with
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'EXtending Interface Science To Atmospheric-pressure Reactions' (EXISTAR).

assistant: **Concept**

This project aims to deliver a step change in our understanding of electrode and catalyst interfaces, by pioneering operando measurement capabilities that can reveal the chemistry and structure of functional interfaces under working conditions in liquid and gas environments at atmospheric-pressures and above. We will exploit enclosed reaction cells sealed with X-ray, electron and neutron transparent windows, extending their operation to conditions of temperature and pressure where industrial catalytic reactions occur, as well as the liquid environments of electrochemical energy storage. These cells will be portable across complementary characterisation tools to reveal the chemical and structural evolution of material interfaces during operation. Solid-liquid studies will focus on electrode materials for Li-ion batteries, that are critical to energy storage for a low carbon economy. This will reveal the degradation mechanisms that lead to capacity fade across varying conditions of stress (T, voltage, rate) during electrochemical cycling. Solid-gas studies will focus on heterogeneous catalysts for sustainable production of useful chemical feedstocks from environmentally harmful waste streams. We aim to reveal the nature of the active sites in catalysts used for chemical synthesis from carbon dioxide, and understand how combining these catalysts with oxide supports influences their activity and selectivity. Relationships will be established between the interfacial structure and function of these materials in terms of their electrochemical cycling performance and catalytic activity/selectivity. This will ultimately inform the design of new functional materials for use in technologies that are critical to a sustainable economy. The scope for research problems that can benefi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Governing sustainable energy-mobility transitions:  multi-level policy mixes, transformative capacities and low-carbon innovations' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

In its recent 1.5°C report the IPCC stressed that global efforts to promote low-carbon transitions need to be accelerated to meet the Paris Agreement. This raises a number of questions for the emerging field of policy mixes for sustainability transitions, such as on the role of actors and multi-level governance in politically contested socio-technical transition processes. In this project, I aim to address these knowledge gaps by asking how low-carbon transitions in the increasingly interconnected energy and mobility systems as major contributors to greenhouse gas emissions can be accelerated. EMPOCI has three objectives:Objective 1: To provide a novel conceptual and empirical understanding of the global interplay between multi-level policy mixes and low-carbon innovations in socio-technical transitions which foregrounds the role of actors and transformative capacity.-> By bridging the innovation and policy studies literatures and comparatively analyzing the increasingly interconnected electricity-mobility-ICT systems in four key countries, EMPOCI will advance the research frontier on transformative policy mixes for low-carbon transitions.Objective 2: To develop and test widely applicable novel methodological tools enabling both deep and broad insights into the drivers and barriers in unfolding multi-sectoral transition processes towards sustainability.-> Drawing on a multi-method research design EMPOCI will provide novel standards for assessing policy, agency and innovation dynamics in politically contested low-carbon transition processes (e.g. survey, big data).Objective 3: To co-design practically relevant multi-actor strategies for accelerating sustainable energy-mobility transitions, thereby supporting the Paris Agreement in combating climate change.-> Based on EMP
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Biotechnological approach to water quality improvement in tropical and subtropical areas for reuse and rehabilitation of aquatic ecosystems'.

assistant: **Innovation**

The main objectives are as follows:* Development of low-cost procedures of water purification by constructed semi-natural wetlands as a strategy for water chain management.* Water chain management by short-term procedures for water reuse and guarantee of access to non-toxic potable water and by long-term procedures for rehabilitation of aquatic ecosystems and for stabilisation of food production in the future.* Plant species from tropical and subtropical areas around the world are cultivated in constructed wetlands and checked for their purification capacity as well as allelopathic effects to eliminate contaminants and harmful bacteria.* Renewable energy sources of solar radiation and wind are used to operate the system and control the water distribution.Expected OutcomeLow-cost and low-tech water purification systems using constructed wetlands, will be developed for drinking water supply of rural communities and distributed to developing countries in the tropics and subtropics. The systems should be adapted to local surface water contamination (e.g. by algal toxins, heavy metals, agrochemicals, untreated industrial and municipal run off). The results of these studies should provide evidence also to develop long-term strategies for the design and construction of semi-natural wetlands with stable plant-soil bacteria-associations for water improvements at the border of freshwater lakes to rehabilitate eutrophicated aquatic ecosystems and to increase biological diversity.The key activities envisaged are:* Plant vegetation from swamps in tropical and subtropical areas are selected for effective purification and detoxification capacity to decrease contamination of water of natural lakes to nutrient contents (e.g. phosphorous, nitrogen) of oligotrophical lakes and to a level
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'MINDing the brain: IRGQ as a molecular switch between degradative and secretory autophagy in membrane quality control and neuroinflammation' (MIND).

assistant: **Innovation**

Neurodegenerative diseases and chronic brain inflammation affect millions and still lack effective, mechanism-based treatments. Failures in cellular quality control such as autophagy fuel neuro-inflammation and neuro-degeneration. Our recent work (Herhaus, Cell 2024) identified IRGQ as a new autophagy receptor which directs cargo either to lysosomal degradation (degradative autophagy) or to membrane presentation and cell release (secretory autophagy). IRGQ is essential in maintaining membrane integrity and limiting inflammatory signalling. Our new preliminary data show that IRGQ loss alters immune-synapse readouts and reveal IRGQ as a scaffold for the autophagy initiation machinery and vesicle trafficking regulators—clear motivation to probe brain inflammation and early neurodegeneration in vivo. Our proposal, MIND (Membrane quality control and IRGQ in Neurodegeneration) combines strong molecular biology with in vivo disease relevance. Building on recent structural and functional evidence that IRGQ binds core autophagy proteins and controls immune cargo, we will: (1) define, with precision, how IRGQ engages the autophagy machinery to route cargo; (2) map how stress reshapes this routing and defines inflammatory signalling; and (3) test consequences in the brain across the lifespan.We bring unique resources. A novel, unpublished, viable full-body IRGQ knockout mouse, with aged cohorts already available; and advanced molecular expertise in autophagy combined with cutting-edge imaging and proteomics platforms to conduct cell-based screens, and multi-omics and histopathology of our mouse model. Within 24 months, we aim to characterise IRGQ as a molecular switch that coordinates degradative and secretory autophagy to safeguard cellular integrity and restrains neuroinflammati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Why do plants make (p)ppGpp?' (GREENMAGIC).

assistant: **Innovation**

Under stress bacteria accumulate the potent chemical messenger (p)ppGpp, which drives global changes in transcription that allow the bacteria to adapt and persist. Remarkably the ability to synthesise (p)ppGpp is conserved in plant chloroplasts, organelles that are descended from an ancient prokaryotic endosymbiont. However, very little is known about the role (p)ppGpp plays in plants. We propose to (a) artificially manipulate (p)ppGpp levels and analyse the downstream responses of the plant, and (b) examine how (p)ppGpp synthesis is controlled and how these control mechanisms are wired into known stress and developmental signalling pathways. Discovery of the role of (p)ppGpp in plants will allow us to better understand how plants adapt to stress, how chloroplast development and photosynthesis are regulated, and how an ancient endosymbiont became integrated into a eukaryotic cell. This knowledge will be important for improving crops to face the challenges of a changing climate and uncertain energy supplies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Effective Random Methods in Discrete Mathematics' in the context of a Horizon Europe call.

assistant: **Objectives**

The probabilistic method, pioneered by Paul Erdős, can show the existence of combinatorial objects without hinting how to construct them effectively. Recent developments concerning the constructive version of Lovász Local Lemma (LLL) showed how to modify the  probabilistic method to make it effective. This proposal lists four research directions in analysis, combinatorics, and cryptography, where this method opened new possibilities to go beyond our present knowledge.1. The measurable version of LLL is the question whether the object, guaranteed by LLL, can additionally be measurable? In some special cases the answer is in the affirmative. What are the constraints which guarantee measurability, and when is it impossible to achieve this? Results are relevant for classical problems of measure group theory.2. A novel approach improving the celebrated sunflower lemma also uses effective probabilistic tools. We will use a similar approach to improve the best estimates for multicolor Ramsey numbers, Schur numbers, and to explore a number of other classical problems.3. Several new phenomena arise in extremal graphs when either the vertices or the edges are linearly ordered. To investigate them we use methods from effective probabilistic sampling. The answers would be relevant in discrete geometry, algorithm design, etc.4. An emerging phenomenon in certain cryptographic primitives including secret sharing will be addressed: relaxing the strict requirements of correctness by allowing negligible errors can lead to significant improvement in efficiency. It is a direct consequence of the mostly unknown structure of the boundary of the entropy region. Using tools and results from the other parts of the project we will explore this boundary giving hints for why, and tools for where a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Development of an innovative integrated PRoperty MEasuring transponder, for non-contact monitoring of material quality' to be submitted under Fourth Framework.

assistant: **Abstract**

Maintenance activities and costs in buildings are largely determined by the influence of moisture on constructing materials. For instance (parts of) window frames are replaced due to wood-rot caused by funghi. Also the lifespan or performance of other construction materials such as concrete and insulation are influenced by moisture. There are techniques to support maintenance activities. However, they measure the relative moisture percentage with a low degree of precision and reliability. Moreover, the present measurement technique is of a destructing character since it damages protecting coatings because of penetration in the material. Proposers want to realize a new measuring system that is based on an integrated measurement and transmitting device that can realize non-contact monitoring of moisture content, temperature (or other properties) in different construction materials. Through measuring of impedance as a function of moisture content, high precision (0,5 % deviation) and reliability of measurement results can be obtained. This gives insight in the state of the product, construction, building etc. in which the material is used. Through preventive maintenance endurance of materials could increase tremendously. By implantation of a transmitting monitoring device in the material, non-contact monitoring of properties becomes possible. This is only possible if an innovative technique of integrated measuring and transmitting that works on an extremely low energy-level, is realised. As especially valuable environmental impact is seen the possible replacement of tropical wood and other environmentally unfriendly materials in construction (PVC) by softwood. On the basis of a life cycle analysis on instruction of the Ministry of Environment in the Netherlands, soft wood
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Continuum State Cellular Automata and Random Equations - Applications to urban growth and traffic models' under Sixth Framework.

assistant: **Concept**

The proposed research project focuses on a generalization of Cellular Automata (CA) describable using both ODE and random differential equations (RDE). They are models capable of quantitative forecast as well as the same modelling flexibility of classical CA.The use of a continuum state space permits to use new ideas about model’s calibration and validation e.g. defining a meaningful distance on the configuration space and using optimization techniques. We shall call them Interaction Based Dynamical Systems (IBDS), because they seems useful to model complex systems formed by agents locally interacting.Objectives of the project are:- Mathematical definition of IBDS generalizing the work done by the reintegration research group about continuum state CA modelling of urban growth- Construction of the probability space associated to an IBDS. This is the mathematical framework where to prove the following objectives- Study of the related differential equations. Every IBDS can be described using both an ODE, in case of infinitesimal standard deviation, and an infinite system of RDE (one for each moment of the state variables)- Numerical solution of this system of RDE5.- Construction of a traffic model using IBDS6.- Numerical study of bifurcations using ODE and RDE7.- Analysis of the possibility to generalize the MCF work of the proposal’s researcher to extend the real field adding random infinitesimal fluctuations.- Use of this extension to study IBDS.These objectives will be achieved using standard probability theory methods, the infinitesimals of researcher’s MCF, programming in Matlab and interdisciplinary work at the host institute.The possibility to introduce a new and flexible type of modelling tool for the study of complex systems is of great importance both for EU and