RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'EFFECTS OF LAND COVER CHANGE AND LAND ABANDONMENT ON SEDIMENT YIELD IN SEMIARID MEDITERRANEAN CATCHMENTS USING REMOTE SENSING, GIS AND FIELD TECHNIQUES' (SEDIMED) targeting Seventh Framework.

assistant: **Abstract**

The focus of this research project is to quantify the effect of historical land use/-cover change onerosion by combining conventional geomorphic methods, remote sensing and innovative geochemicaltechniques. The Western Mediterranean region is the core region of this project, as it was identified by theUnited Nations as one of the regions mostly affected by desertification in Europe. Its main objective is toprovide quantitative data on the historical evolution of erosion processes in relation to past and present landuse/-cover change in the Western Mediterranean region. Data collected in the project on the anthropogenicacceleration/deceleration of erosion will contribute to a better understanding of desertification in the WesternMediterranean region. Furthermore, the expertise that will be developed in this research project will allowplacing present land degradation processes in their historical context.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Archaeology of Dress along the Middle Nile' in the context of a Horizon Europe call.

assistant: **Objectives**

100 years of archaeological research along the Middle Nile has yielded partial knowledge of the history of Sudan and Nubia. To date, the focus has been on the public life of the sedentary elite. Other identities remain invisible and cultural frameworks tend to be restricted to binary oppositions (e.g. sedentary vs. nomads, Pharaonic vs. African influences). Going beyond the monumental remains, the Fashioning Sudan project will focus on a long-neglected and much more intimate aspect of the Sudanese material world: dress practices. This pioneering approach will merge different academic fields such as archaeology, textile and animal skin research, palaeoproteomics, and socio-cultural theory. Thanks to its arid climate, Sudan is one of the rare places on Earth where archaeological textiles and skins are well preserved and in remarkably high numbers; but despite its potential, this treasure trove of information is seldom exploited by historians or archaeologists. Fashioning Sudan will use garments as a privileged medium to reveal past identities, bringing new and more representative knowledge about the populations of ancient Sudan and highlighting the entanglement of dress practices in the fabric of society. The project will encompass the high-resolution analysis of textile and animal skin garments from the Bronze Age to the Late Medieval period, in close connection with their archaeological context. The results will reveal which animal and plant species were exploited, as well as skills and craft dynamics. It will then question how to use clothing and socio-cultural theories to reveal previously unknown aspects of past Sudanese lives. Fashioning Sudan will renew our academic approach to past identities along the Nile thanks to interdisciplinary research uniting under-exploi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'High Quality Fuel Production System from Plastics, Industrial Oil and Refinery Residues.' (2014-2020).

assistant: **Concept**

Kurata Systems Process represents an alternative production method of high added value fuels from residues such as plastics, used industrial oil and refinery residue. We obtained diesel C and other fuels that meet the legislation specifications. Although we have an adequate quality fuel to introduce into the market, the limitation in our productivity scale keeps off the commercialization of our fuels. Based on our pilot-plant results, the objective of this project is to scale-up a continuous process with three different processing lines for each feedstock (plastic, industrial oil and refinery residue) in a new plant.This project involves an alternative source of fuel, reducing energy supply risks with the corresponding dependance of other countries.  Additionally Kurata is involved as a waste management project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Asymmetric Fluorocyclisations' in the context of a Seventh Framework call.

assistant: **Objectives**

Fluorinated oxygen- or nitrogen-containing heterocycles (lactones, lactams, pyrrolidines and tetrahydrofurans) are important compounds with application in the pharmaceutical and agrochemical industry or as performance compounds in material science. Enantioenriched F-heterocycles with the fluorine substituent on a stereogenic centre are of particular interest but are not easy to access using known protocols. The aim of this proposal is to develop an asymmetric route (including a catalytic variant) to fluorinated heterocycles from prochiral starting materials relying on a fluorocyclisation as the key step. The project builds on literature and data from our laboratory showing that activated and allylsilanes are amenable to fluorocyclisation. Two approaches will be considered to access enantioenriched fluorocyclised heterocycles, based on the use of both novel chiral N-F reagents and well-documented fluorinated cinchona alkaloid derivatives.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Chytridiomycosis resistance through sexual selection'.

assistant: **Concept**

Sexual selection (SS) is a strong evolutionary force that can promote or inhibit adaptation to environmental challenges. When populations face novel pathogens, SS can influence their persistence by impacting the spread of resistance alleles. The major histocompatibility complex (MHC) encodes proteins that recognize pathogens. Many vertebrates preferentially mate with partners carrying beneficial MHC alleles, conferring higher resistance to the offspring.Here, I propose to study the role of SS in the evolutionary dynamics of amphibian resistance to chytridiomycosis (pathogen Bd), an emerging infectious disease that is causing population declines and extinctions worldwide; with poison frogs, a species-rich group in which the strength of SS differs between species. i) I will test whether mate choice is influenced by MHC and infection status of both partners. ii) I will use theoretical models to predict under which circumstances SS can accelerate the evolution of disease resistance. iii) I will use population ecology to evaluate the association between the strength of SS and species’ susceptibility to Bd in natural populations.This project will provide fundamental scientific knowledge on the relationship between SS and the evolution of immunity by exploring the interaction between Bd and amphibian MHC. It builds on the recent insight that natural selection drives MHC evolution in amphibians, and originally explores the role of SS in this process in a uniquely integrated experimental, theoretical and field ecological fashion. I have worked with Bd throughout my academic career; this project allows me to focus on the hosts, which has been the target of fewer studies and is in dire need of conservation. The project will be conducted at the University of Groningen under the sup
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Realizing Enhanced Safety and Efficiency in European Road Transport'.

assistant: **Objectives**

The REACT project will represent a breakthrough towards the long-term vision of reducing traffic deaths significantly and improving transport infrastructure efficiency. Integrating state-of-the-art technologies, REACT will sense natural and infrastructure conditions within and in the vicinity of each equipped vehicle, will transmit sensed real-time data to a central server where they will be analyzed by a set of sophisticated prediction and decision-making models, and will generate 1) safety alerts, speed and route recommendations, to be communicated to specific vehicle drivers; and 2) relevant information for road and law enforcement authorities. By using mobile vehicles sensors, REACT will ultimately cover all roads, and not just inter-urban routes where existing traffic management systems tend to be located. By having the capability to detect driver behaviour and condition, REACT has the potential to exert a strong favorable impact on road safety. These are critical features because most traffic deaths occur outside of urban areas and because driver error is the main cause of traffic fatalities. A warning of potential danger from the REACT system will raise driver vigilance and reduce the risk of an accident. In areas with existing traffic management systems, REACT will share data and results with the existing system and would operate in close coordination with the regional road authority. Initial sensors will sense both road and infrastructure condition. Wireless technology will transmit data from sensors to a central server. Field tests of the prototype system, using several sensor-equipped vehicles, will occur in stages in the region of Munich. The system in Munich will be coordinated with the local traffic management system.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Functional dissection of core spliceosomal mutations causing Retinitis Pigmentosa.' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

More than 95% of human genes undergo pre-mRNA splicing, and alternative splicing of mRNA precursors represents a prevalent mode of gene regulation. Errors in this process are often the origin of of disorders. Most of splicing-related diseases are caused by perturbation in pre-mRNA transcripts which lead to their aberrant processing. Interestingly, a fraction of mutations affecting directly splicing factors, including core spliceosomal components, has been linked to a group of pathologies. Particularly intriguing are variants of the key spliceosomal subcomplex U4/5/6 tri-snRNP, associated with Retinitis Pigmentosa. Why these mutations lead to highly tissue-specific phenotypes, rather than general toxicity cause by a global block in splicing, remain unexplained. The proposed research aims to increase our understanding of the molecular mechanisms underlying the effects of these mutations and shed light on the basis of the disease. To functionally dissect these variants, I will combine spliceosomal network approaches (I) with genome-wide transcriptome analysis (II) and detailed biochemical and structural studies (III). Mechanistic insights derived from these analyses will help to identify transcripts that are predominantly sensitive to these mutations and that could be behind their pathogenic effects (IV). This work will allow us to better understand the function of key splicing factors, as well as the basis for their effects on splice site selection and their contributions to Retinitis Pigmentosa pathology.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Monitoring bone healing around endosseous implants: from multiscale modeling to the patient’s bed'.

assistant: **Objectives**

Implants are often employed in orthopaedic and dental surgeries. However, risks of failure, which are difficult to anticipate, are still experienced and may have dramatic consequences. Failures are due to degraded bone remodeling at the bone-implant interface, a multiscale phenomenon of an interdisciplinary nature which remains poorly understood. The objective of BoneImplant is to provide a better understanding of the multiscale and multitime mechanisms at work at the bone-implant interface. To do so, BoneImplant aims at studying the evolution of the biomechanical properties of bone tissue around an implant during the remodeling process. A methodology involving combined in vivo, in vitro and in silico approaches is proposed.New modeling approaches will be developed in close synergy with the experiments. Molecular dynamic computations will be used to understand fluid flow in nanoscopic cavities, a phenomenon determining bone healing process. Generalized continuum theories will be necessary to model bone tissue due to the important strain field around implants. Isogeometric mortar formulation will allow to simulate the bone-implant interface in a stable and efficient manner.  In vivo experiments realized under standardized conditions will be realized on the basis of feasibility studies. A multimodality and multi-physical experimental approach will be carried out to assess the biomechanical properties of newly formed bone tissue as a function of the implant environment. The experimental approach aims at estimating the effective adhesion energy and the potentiality of quantitative ultrasound imaging to assess different biomechanical properties of the interface. Results will be used to design effective loading clinical procedures of implants and to optimize implant conceptio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'DEVELOPMENT OF AN INTEGRATED KNOWLEDGE BASED DECISION SUPPORT SYSTEM FOR DIFFERENTIATED AGRICULTURAL PRODUCTS'.

assistant: **Objectives**

Background : The drastic changes occuring in the EU towards the actual establishement and realisation of a Single integrated European market bring new opportunities and challenges to farmers and their cooperatives. Agribusiness industries face a stiff competition originating mainly from the EU trade barriers# removal and the rapidly changing marketing environment fo the single European market. Marketing of agicultural products has not yet taken full advantage of the methodological advances in behavioural sciences, economics and quantitative methodologies. A certain need has been identified towards the development and proper utilisation of updated market research tools and methodologies in the field of agricultural management and marketing. Also marketing information systems have been created and adopted in agribusiness firms to a very small extend. Management decision making is based on sporadic information and less on systematically collected and processed data. As a result, the recommended market penetration policies lead quite often to a dead end.The objective is :The aim of the project is to develop a knowledge based decision support system tosupport farmers and relevant decision makers in formulating marketing strategies andfinding optimal distribution channels for novelty agricultural products (olive oil,organic products, niche market products) .Short description of the project :It proposes an integrated approach to the marketing problem of agricultural productstaking into account all the marketing mix variables (product, price, promotion andplace). The system will suport decision makers in new product design anddevelopment, identification of potential market segments, formulation of communication strategy and in forecasting. Specifically, it will allow decisionma
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Design and synthesis of novel analogues of laulimalide as improved microtubule-stabilising anti-cancer agents' to be submitted under Sixth Framework.

assistant: **Abstract**

Despite considerable progress in cancer treatment, there is still a need for novel chemotherapeutic agents with improved pharmacological properties, reduced side-effects and efficacy against otherwise drug-resistant cancers. Laulimalide is a highly potent antimitotic agent, isolated from marine sponges, which inhibits the proliferation of cancer cell lines at the low nanomolar level. By sharing the same microtubule-stabilising mechanism as TaxolÂ® and retaining activity against multidrug-resistant cancer cells, laulimalide presents a promising lead structure for the development of a new class of anti-cancer agents. In the proposed project, structurally simplified analogues of laulimalide will be designed and synthesised in order to investigate structure-activity relationships and the mechanism of action, as well as improving the chemical stability. In this context, the preferred bioactive conformation of laulimalide will be probed and the structural requirements for potent cytotoxicity explored.The applicant will improve her research training and expand her knowledge in the synthesis of biologically active molecules with therapeutic potential, at the same time participating in multidisciplinary research at the interface of chemistry, biology and medicine. Moreover, she will work on a totally different topic from her PhD studies and thus acquire new knowledge and expertise. These additional skills and complementary experiences will lead in turn to an exceptionally well-trained researcher, with enhanced profess ional maturity and independence, providing lasting long-term benefits in her future career. In addition to the high scientific standards provided by this postdoctoral research experience, the fellow would profit from the excellent infrastructure and the opportuniti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Esqc-01' under Fifth Framework.

assistant: **Concept**

The European Summerschool in Quantum Chemistry is the most important summer school in the subject in Europe (and in the world). It started in 1989 and has since then been given each second year. An extra school was held in the year 2000 in Italy, sponsored by Italian authorities. The number of students, who has participated so far, is close to 500. The students (written) evaluation of the school has always been very positive.The goal of the school is to introduce the participants into modern methods and computational techniques in quantum chemistry. More and more scientists in different field of chemistry are using theoretical methods in their research, either as a technique per se, or as a complement to experimental work. As a result there is a growing need to acquire the background knowledge necessary for a skillful use of these methods. ESQC was started with the aim of disseminating such knowledge.The emphasis of the school is more on understanding than on the technical aspects of methods, and much time will be devoted to the discussion of different electronic structure problems and the choice of appropriate methods for their solution. The duration of the school is 14 days and in 2001 the school, starts August 19. There are 31 lecture hours and 20 exercise hours. The following lectures will be given (lecturers within parentheses): Basis sets, Integrals, and SCF methods (R. Ahlrichs); Chemistry in condensed phases (V. Barone) ; Density Functional Theory (N. Handy) ; Energy derivatives and Geometry Optimization (T. Helgaker) ; Mathematical Tools in Quantum Chemistry (P.-A.)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'RENEWABLE ENERGY ACTIONS LEVERAGING INNOVATION TOWARDS ZERO EMISSIONS IN EUROPE'.

assistant: **Concept**

The REALIZE project aims to present a carefully selected and pre-qualified portfolio of new renewable energy generation technologies to the EU Innovation Fund (IF) through proposals resulting from successfully completed Horizon projects in Renewable Energy Sources (RES). The project will support IF project promoters to win major Innovation Fund support or propose alternative funding opportunities at EU, national and local level. Intense support will be given to ten technology partners in the consortium building on their results from 15 pre-qualified Horizon projects. From these, we will prepare seven IF proposals spanning a variety of sectors: Concentrated Solar Power, wind, solar thermal and solar photovoltaics, ocean energy and biofuels as energy-producing installations and as manufacturing projects for small-, medium- and large-scale calls. Their technology will be profiled. REALIZE will also reach out to the broader renewable energy community, with conferences and written material addressing IF’s selection criteria; sharing “lessons learnt” (including with Innovation Fund’s designers) and explaining the complementarity of different public funding programmes. Deep collaboration with other projects funded under the same call topic is foreseen but not counted upon.


**Keywords:** Innovation Fund application support,  H2020 projects exploitation