RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Improving Children's Auditory Rehabilitation' in the context of a Seventh Framework call.

assistant: **Objectives**

Improving Children’s Auditory REhabilitation (iCARE)Communication through language is vital to develop and maintain everything around us. By 15 years of age, about 5 out of 1000 children suffer from a moderate, severe or profound hearing impairment that can potentially affect communication, learning, psychosocial development and academic achievement if not appropriately handled.The EU promotes the active inclusion and full participation of disabled people in society. However, full active inclusion in an oral society can only be achieved through cooperation and involvement across disciplines (language, psychology, audiology, engineering, special education,…). It is therefore of fundamental importance to approach the inclusion of children with hearing impairment in an interdisciplinary manner, and to train future experts to adopt such principles in their research and practice.The objectives of improving Children’s Auditory REhabilitation (iCARE) are twofold: 1) to provide training create a new generation of researchers capable of exploiting the synergies between different disciplines to optimize spoken communication in children with hearing impairment, and 2) to combine research across disciplines to develop novel methods, training skills and procedures for improving auditory rehabilitation.iCARE is an international and interdisciplinary consortium from academia, industry and socio-economic agencies. The proposed training consortium is unique because the partners are specialized in a variety of disciplines, both technical and non-technical, all of utmost importance to the core issue: optimizing inclusion of children with hearing impairment in an oral society through evidence-based research. The consortium will provide comprehensive training of fellows to become ‘communica
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The Tocharian Trek: A linguistic reconstruction of the migration of the Tocharians from Europe to China' under Horizon 2020.

assistant: **Concept**

The long trek of the Tocharians from Europe to China is one of the most disputed issues in the migration history of Eurasia. Tocharian is an extinct branch of the Indo-European language family, which includes a.o. English, Latin, Greek and Sanskrit. The Indo-European languages stretch in one uninterrupted belt from Ireland to the Sea of Bengal, but Tocharian, discovered in manuscripts from the Tarim Basin in Northwest China dating from c. 500–1000 CE, is a notorious exception to this geographic distribution.The common ancestor of the Indo-European languages, Proto-Indo-European, can be hypothetically reconstructed and is often located in the east of present-day Ukraine. Therefore, speakers of early Tocharian must have made a long trek eastward before they settled in the Tarim Basin. Archaeological and genetic evidence suggests that they first moved east to southern Siberia around 3500 BCE and then south to the Tarim Basin in China, where they may have arrived as early as 2000 BCE. The arrival of the Tocharians in the Tarim Basin is possibly linked to ancient corpses found there: the so-called Tarim Mummies.Curiously, linguistic evidence has mostly been neglected. Therefore, the proposed project aims to provide an integrated linguistic assessment of the hypothesised migration route of the Tocharians.Languages preserve precious information about their prehistory through the effects of language contact. Through close scrutiny and periodisation of the different layers of contact of Tocharian and its prehistoric neighbours, the project will reconstruct the migration route of the Tocharians from the Proto-Indo-European homeland all the way to China.The crucial Siberian phase of the migration shows the groundbreaking nature of the approach. Genetic evidence points to influence
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Quantum Dynamics Beyond the Born-Oppenheimer Picture: Making the most of wave function and trajectory-based approaches' (BeBOP), addressing dissemination and exploitation.

assistant: **Impact**

The experienced researcher, Dr. Guillermo Albareda, and the host supervisor, Prof. Angel Rubio, aim at developing a new predictive and practical approach that overcomes the difficulties that current methods have to treat the correlated electron-nuclear dynamics in complex systems. Up to now, most of the methods to describe the coupled motion of electrons and nuclei have been based on the Born-Huang expansion that fails to meet the appropriate trade-off between accuracy and efficiency for large systems. Based on the “conditional decomposition” (CD) framework recently introduced by the experienced researcher, the proposed research relies on the premise that the radically different mathematical grounds of the CD approach will lead to a paradigm shift in how ab-initio nonadiabatic molecular dynamics is numerically approached. The program starts with the fundamental method development based on the CD framework, goes through a systematic performance test to reach the desired accuracy/efficiency trade-off, and will be implemented in a computational platform to be applied to study large systems such as artificial light-harvesting complexes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Identification of genes and gene products involved in oncogenic ras-induced g1-growth arrest' (1994-1998).

assistant: **Concept**

Research objectives and content Over the last several years considerable progress has been made in understanding cell cycle controlling mechanisms. The identification of the negative growth regulator p53 and pl6ink4a and their involvement a; tumor suppressor proteins caused a major breakthrough in cell cycle research. In contrast to p53, very little is known about the extracellular or intracellular signals leading to the induction of p1 6-mediated grows! arrest. So far only oncogenic Ras has been shown to be a mediator of pl6ink4a-induced G1-growth arrest together with increased p53 in primary-like cells. Therefore, it is of outstanding interest to identify (novel' genes and gene products involved in oncogenic Ras-mediated pl6ink4a and p53 induction resulting insenescent-like growth arrest. The approach of retroviral transduction of a specially designed vector facilitates the selection of highly Ras-expressing cells by FACS-Analysis of green fluorescent protein coexpressing a normalized cDNA library.The identification of mediators involved in the Ras-induced G1-growth arrest will make a significanl contribution to the general understanding of both normal growth regulation and tumorigenesis. Training content (objective, benefit and expected impact) The objective of this training is to broaden the methodological repertoire of molecular ,,state of the art' techniques, in particular the use of the retroviral transduction method of primary cells. The handling of such retroviral constructs with an oncogenic Ras-fused green-fluorescent protein (GFP) as a selection marker for FACS-analysis can be easily adopted to other biologically relevant questions providing a powerful tool for future projects. Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'CHIral SMArt honeyCOMB' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

The purpose of the proposed project is to develop a new concept of cellular chiral material having Negative Poissons ratio with enhanced mechanical and dielectric properties, able to include in its microstructure and sensor and actuators to be implemented in innovative smart sandwich structures. The novel structural core concept will have paradigmatic properties compared to classical honeycomb materials currently used to manufacture sandwich components with complex shapes, and multifunctional active chara cteristics for stuctural health monitoring and electromagnetic compatibility applications, with no detriment to the structural integrity of the components. At the moment, no single core material can be used in a multifunctional design contect like the on e the consortium is proposing to develop. The project is divided in workpackages dedicated to base multiphysics modeling, sandwich structure design, embedding structural health monitoring and microwave absorption capabilities with custom-designed microse nsors and actuators in the material configurations. The multiphysics properties of the chiral material will be benchmarked against the ones of available core solids for sandwich applications to assess the engineering feasibility of the proposed material a gainst current technology. Separate workpackages are dedicated to Multidomain design recommendations and management of the consortium. A network consisting of production companies, research institutes and universities will achieve the project goals. The know-how developed will be ideal to stimulate the development of intellectual properties, innovative end-user products and technology transfers. Dissemination through conferences and a special workshop organised at the end of the project will raise the a wareness about
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'twiN-on-a-chip brAins for monitoring individual sleeP habits' (NAP) targeting Horizon Europe.

assistant: **Abstract**

Insufficient sleep is an under-reported epidemic and sleep disturbances are common early signs of neurodegeneration. Clinical research is currently challenging the assumption that human sleep is a one-fits-all phenomenon: breaking new grounds into sleep research is needed. NAP makes real the study of individual sleep pathophysiology through a new science-to-technology paradigm merging in vitro modelling, allometric scaling, signal processing and micromanufacturing. NAP targets five breakthroughs: 1) the development of the first model enabling the accurate study of individual sleep, 2) the realization of the cyborganoid, i.e., the next generation of biohybrid model of the human brain, 3) the setup of an experimental procedure to mimic sleep in vitro accounting for a person’s lifestyle, metabolism and genetic makeup, 4) the exploitation of allometry to obtain meaningful information from in vitro to humans and 5) the delivery of the first tool for Parkinson’s Disease (PD) early diagnosis. As a Proof of Principle, NAP will identify the effects of sleep deprivation and detect sleep-related signs of PD in a personalised perspective. In the long-term, NAP will move Europe to lead sleep research and innovation through its envisioned technology: a predictive medicine twin-on-a-chip allowing the public at large to be routinely screened for i) checking their sleep health, ii) being warned about the consequences of sleep loss, iii) predating PD and other neuropathies characterized by sleep anomalies. This will be of benefit for science, society and economy.  NAP Proof of Principle will deliver the first tool for accurately extrapolating biological parameters from in vitro to humans. The identification of individual sleep needs will allow the targeted detection of people suffering f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Thermochemical imaging of the Earth’s mantle: Global inversion of seismic waveforms, satellite gravity data and surface elevation' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The thermochemical structure of the Earth’s lithosphere and underlying mantle controls fundamental dynamic processes including volcanism, seismic activity and surface topography variations. The growth of very large terrestrial and satellite geophysical data sets over the last few years, together with the advancement of petrological and geophysical modelling techniques, now present an opportunity for global, thermochemical 3D imaging of the lithosphere and upper mantle with unprecedented resolution. Established methods of seismic tomography and gravity data analysis constrain distributions of seismic velocity and density at depth, both depending on temperature and composition of the rocks within the Earth. However, independent modelling and inversion or a simple combination of models based on gravity and seismic data alone suffer from the intrinsic non-uniqueness of each type of models. Thermodynamic links between seismic velocities, density, temperature, pressure and composition within the Earth can now be modelled accurately using new methods of computational petrology. This project combines state-of-the-art seismic waveform tomography (using both surface and body waves), newly available global gravity satellite data (geoid and gravity anomalies and new gradiometric measurements from GOCE mission) and surface elevation within a self-consistent thermodynamic framework. A new method for global thermodynamic tomography will be developed and applied to obtain a robust and, at the same time, detailed thermochemical model of the Earth’s lithosphere and upper mantle.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Developing Innovative Outreach and Dialogue on responsible nanotechnologies in EU civil society' (NANODIODE) under Seventh Framework.

assistant: **Objectives**

Stakeholder engagement and dialogue are essential to the responsible development of nanotechnologies in Europe. NANODIODE establishes an innovative, coordinated programme for outreach and dialogue throughout Europe to support the effective governance of nanotechnologies. The project integrates vital engagement activities along the innovation value chain: it combines ‘upstream’ public engagement (by way of dialogues that integrate societal needs and expectations into the policy debate) with ‘midstream’ engagement (by organising open innovation workshops at the level of R&D) and ‘downstream’ strategies for education and communication.The overall objectives of NANODIODE are to:• Develop new strategies for outreach and dialogue along nanotechnology value chains;• Organise engagement and dialogue at the 'upstream' level of research policy;• Enable processes of co-creation during research and innovation;• Professionalise nanotechnology education and training;• Establish an innovative programme for outreach and communication on nanotechnologies;• Assess the impact of the project’s activities and provide policy feedback with a view to Horizon 2020.The consortium brings together a strong network of partners from various backgrounds and extending across Europe (representing academia, industry, civil society, education and communication). Many partners bring their experience as coordinators of earlier European projects (such as NANOCODE, NANOREG, NANOEIS, NANOCAP, NANOPLAT, OBSERVATORY NANO, NANOPINION, NANOCHANNELS and NANOBIORAISE). This will allow the project to look back and identify best practices based on existing experience - and developing new, innovative models and tools for outreach and dialogue when necessary. The project will also look ahead: as Horizon 2020 unfolds, t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'New Mobile services at big events using DVB-H broadcast and wireless networks' under Sixth Framework.

assistant: **Concept**

Mobile services are a hot topic nowadays. Deployment of TV on Mobile has started some time ago with the availability of high performance 3G networks and phones. In a lot of European countries and the USA the first generation of TV services based on a mobile broadcast standard is being tested and evaluated and the commercial rollout is almost starting.MOBISERVE has the objective to do research in the field of convergent interactive services using rich-media information. Not all the standards and related technology is available yet. MOBISERVE will design and evaluate innovative solutions for these second phase" highly interactive services. The starting point will be new user scenarios related to big events like the Olympic games in Beijing in 2008. Two user scenarios will be defined at the games itself. Moreover, one scenario how to "relive" the games at home using the home cinema and another one related to the experience of the service at a hotspot through service relay. MOBISERVE will access the value and user feedback regarding the services by a trial during the Olympics.Key results are expected in the field of:- New interactive rich-media service scenarios for public visiting sports events.- Enabled by an innovative interactive service application platform.- The value of the service is tested with a user focus group during a trial at Olympics Beijing.- An adaptation to software, API's and related standards to enable convergent services in mobilephones originating from various sources (e.g. DVB-H, GPRS, WLAN).- Technology to deal with (electronic) coexistence of multiple channels in a terminal.- Technical options to "relive" the sports events experience at home and through a service relay at a hotspot."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'MULti-Tumour based prediction and manipulation of Immune Response' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Only few patients respond to tumor treatment as desired. Treatment heavily relies on host tumor interactions, including exploiting the host immune response against the tumor. The underlying mechanisms of host tumor interaction are largely unknown, guidance on specific intervention is missing. To improve outcome, better understanding of tumor-host interaction is needed. Large numbers of molecular snapshots will provide increased phenotyping coverage and better represent tumor-host evolution over time. In an innovative approach, MULTIR aims at investigating not a single tumor entity, but at compiling data from melanoma, lung and bladder cancer (most drugs target specific molecular features, irrespective of the tumor origin) to identify with high power the critical elements in the tumor-host interaction responsible for therapy response. In a multi-disciplinary approach involving leading clinicians, immunologists, experts in omics, digital technologies, social sciences and patient representatives from 10 EU countries and beyond, and an extensive outreach plan to ensure rapid transfer of MULTIR output to society, MULTIR combines existing multi-layer (epidemiological, genetic, clinical, pathologic, imaging, molecular) data from major studies on these tumors, using AI-based approaches to unveil functional modules regulating tumor-host interactions followed by validation of findings in models and synthetic patients. Harmonization with major EU initiatives will maximize use of European resources. Impact on all scientific, technological and societal levels is expected, including increased understanding of tumor-host interactions, generation of a unique resource of harmonized data on three major cancer types available to the community in compliance to the legal and ethics framewor