RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Investigation of the signal pathways responible for lineage commitment decisions in the thymus' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

Research objectives and content T lymphocytes can differentiate in the thymus from common precursor cells, into one of two phenotypically distinct lineages, called CD4+ or CD8+ T cells. The signals which dictate which of the two lineages a precursor will mature into are not well understood. In the lab, they have developed an experimental system using mono- and bi-specific F(ab')2 antibody fragments which can be used to alter the fate of developing thymocytes in foetal thymus organ cultures, and cause them to mature specifically into either the CD4 or CD8 lineage. In this proposal I plan to investigate the biochemical basis of this differential signalling in order to gain a greater understanding of how these lineage commitment decisions are made. I shall examine the activation of intracellular signaling molecules downstream of the cell surface receptors using a variety of techniques, including examination of tyrosine phosphorylation and tyrosine kinase activity of molecules which have been previously described as important in T cell signalling. This investigation will promote our understanding of the signals responsible for directing differentiation of cells of the immune system. Training content (objective, benefit and expected impact) The research proposal involves using a variety of techniques including immunology, protein biochemistry and molecular biology, some of which I have experience with, but many will be new to me. The lab has experienced post-docs and technical staff who will train me in techniques that are new, which will greatly enhance my overall practical expertise. In addition the department has an active research seminars and journal club program which will expose me to current ideas and state of the art information in immunology. Links with industry /
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Ultra thinned chip stacking' in the context of a Fourth Framework call.

assistant: **Objectives**

The proposed new, dense stack will be obtained as follows : The chips are thinned down to 5-10 µm and then, using planarization techniques as used in semiconductor processing, the 3D stack is formed on a silicon substrate by depositing layers of dielectric onto which a metallization pattern is formed. The thinned chips are placed on top of each dielectric layer and the vertical interconnection is achieved with metallized vias. The final stack has a thickness comparable to that of standard silicon chips.Therefore UTCS results in a multichip miniaturisation having the same physical dimensions as monolithic integration without the drawbacks.UTCS will deliver a new, very dense, 3D stacking technology for semiconductor chips. This very dense, ultra-thin stacking technology is of interest to all electronics industries where size and weight are important for product acceptance. These include all portable applications like telecom terminals, PDAs, portable computers, medical implant, etc., and aerospace where both in satellites and in avionics weight and size are major parameters.Another advantage for industry is the possibility of using standard chips from different vendors, therefore applicable in the short term without the need of expensive re-designs.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Media-Information Sans Frontieres' under Fifth Framework.

assistant: **Concept**

The aim of MEDIA-ISF is to establish a new virtual business network organisation opening new dimensions for small and medium size enterprises and individuals in Europe. The offered three level structure of information service delivery helps to overcome the language borders and to establish quick and efficient information sharing and working relations among participants of the network. Covering regions in the member states and in the candidate countries from the beginning, the new structure facilitates the enhancement of the pre-enlargement co-operation at the level of small and medium size enterprises among the present and future members of the Union. The business case comprises a multi-media based and interactive information service focusing on the EU enlargement process, the regional policies and the SME sensitive market and legislation developments.OBJECTIVESThe objective of the MEDIA-ISF model is to demonstrate the sustainability of the generic virtual network organisation promoting early and broad adoption of novel technologies, applications, business processes and organisational practices targeted at SMEs. The sustainability of the information network organisation providing business to business and business to customer relations improves the equal base participation of SMEs in the global digital economy, helps Enlargement countries to exploit their strength and increases the interaction and networking among different regions and business sectors. The novelty of the model comes from the unique combination of different type of services customised for different sectors and regions in the same structure, enhancing business co-operation, showcasing the benefits and facilitating their deployment in SMEs.DESCRIPTION OF WORKThe MEDIA-ISF model is building from existing bl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'A quantum computer based on electron spins in carbon nanomaterials' in the context of a Seventh Framework call.

assistant: **Objectives**

I will create a two-qubit universal quantum computer based on electron spins a carbon nanotube. Nanotubes are outstanding host material for spin qubits, because they allow hyperfine decoherence to be completely eliminated. Very recently, I demonstrated  the first single qubit in a nanotube, using electric fields combined with a bend in the nanotube to coherently control an electron's spin. This project will realize the additional elements for a computer: high-fidelity qubit readout, a two-qubit gate, and long-lived quantum memory.The objectives are threefold. First, I will perform single-shot readout by incorporating radio-frequency single-electron-transistors  into a qubit device. Using established spin-to-charge conversion techniques, this will allow independent readout of multiple qubits.  Second, I will use the exchange coupling between adjacent nanotube quantum dots to implement a universal two-qubit gate. Finally, I will create a long-lived quantum memory based on spin-active endohedral fullerene molecules chemically attached to the nanotube. These molecules have already shown outstanding quantum coherence properties in ensembles, which I will exploit for devices for the first time. The end goal is a device capable of implementing arbitrary two-bit quantum algorithms, opening the way to a scalable quantum computer based on carbon electronics.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Modeling dna statistical and dynamical properties'.

assistant: **Innovation**

Research objectives and content The available amount of sequences J DNA allows to detect statistical properties that can be interpreted as constraints due to gene functioning anti regulation. Different models for pr`-.u-iotic and eukariotie DNA have been proposed. In parlicular, our attempts to understancd DNA heyontl[?] the nucleotide correlation along the chain made it possible for us to establish a connection between nucleotide statistics and the geomeirieal l'olcding ot' the DNA molecule in eukariotic cells. Time-series analyses will he either inverted or optimised and used, together with those in literature, to extract such information. Together with the biological information available in literature (and also from a close cooperation with with professional biologists), this will allow us to refine our statistics with cukariolie and prokariotie DNA sequences and, compare them with complete genomes available. Exeitation transport properties ol DNA will be studied, together with the influence of nucleotide statistics and correlations on the classical or quantum models Training content Engineering a group with a great experience and moocis, (-)uanmu' i-.-isp`'it in correlated media, anti solutions will enhance the applicant's expertise in these fields, crucial for the project objectives Links with industry / industrial relevance (22) Providing instruments to control better the integration of alien subtences with [?]hullcrCd genotypes, modified through recombinant DNA techniques.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Curiosity and the Development of the Hidden Foundations of Cognition', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

How do human infants develop complex cognition? We propose that artificial intelligence (AI) provides crucial insight into human curiosity-driven learning and the development of infant cognition. Deep learning—a technology that has revolutionised AI—involves the acquisition of informative internal representations through pre-training, as a critical precursory step to learning any specific task. We propose that, similarly, curiosity guides human infants to develop ‘hidden’ mature mental representations through pre-training well before the manifestation of behaviour. To test this proposal, for the first time we will use neuroimaging to measure the hidden changes in representations during infancy and compare these to predictions from deep learning in machines. Research Question 1 will ask how infants guide pre-training through directed curiosity, by testing quantitative models of curiosity adapted from developmental robotics. We will also test the hypothesis from pilot data that the fronto-parietal brain network guides curiosity from the start. Research Question 2 will further test the parallel with deep learning by characterising the developing infant’s mental representations within the visual system using the powerful neuroimaging technique of representational similarity analysis. Research Question 3 will investigate how individual differences in curiosity affect later cognitive performance, and test the prediction from deep learning that the effects of early experience during pre-training grow rather than shrink with subsequent experience. Finally, Research Question 4 will test the novel prediction from deep learning that, following perinatal brain injury, pre-training creates resilience provided that curiosity is intact. The investigations will answer the overarching q
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Behaviour, knowledge, policy. The philosophy of science perspective on the applications of the behavioural sciences in policymaking.' (EPISTEMEBEHAVIOUR) under Horizon 2020.

assistant: **Objectives**

The project addresses the problems emerging from the application of the behavioural sciences to policymaking. These applications refer to research in cognitive psychology, behavioural economics, decision theory and are supposed to provide the knowledge necessary to make policy that is effective. The aim of the project is to analyse how the latest findings in the behavioural sciences are used in policy contexts, to address the challenges which this use provokes, as well as to advance a novel approach to an analysis of behavioural sciences and policy, informed by philosophy of science.  ‘Nudging’ is an example of a new approach to regulation, elicited by the application of the behavioural sciences to policymaking. This approach has polarized scholars and practitioners into fierce critics and devoted enthusiasts. The project intends to go beyond the topics discussed recently in the debate on nudging and behaviourally-informed regulations, and to demonstrate the salient epistemic dimension of the behavioural sciences applied to policy. It will be argued that only then we able to understand why we are facing the current behavioural turn in public policy, and what type of advice is – and can be – expected from the behavioural sciences in the science-based approach to policy-making.  The analysis advanced in the project follows the methodology pioneered by Helen Longino in her philosophical work on studying human behaviour. The project will be pursued at Stanford Philosophy Department, where Prof. Longino is affiliated, and at Academy of Finland Centre of Excellence in the Philosophy of the Social Sciences (TINT) in Helsinki.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Lipidomics in human development, health and chronic diseases' (LIPHEALTH).

assistant: **Innovation**

Until recently, lipids were considered inert compounds that provide permeability barriers between interior and exterior compartments of cells. It is now recognized they are potent regulators of cell functions, including signaling and gene and protein expression. However, the mechanisms remain unclear. Such knowledge is critical since membrane lipid abnormality has been implicated in type 2 diabetes, high blood pressure and cardiovascular disease.Our strategic aim is to establish a Centre of Excellence in Membrane Lipid Research for Europe by integrating knowledge of membrane lipids, genomic and proteomics. It will be realized by enhancing the research capability of a critical mass of multi-disciplinary researchers of the host institute by recruiting high calibre and experienced researchers and secondments of staff to the institutes of our two partners, which have a complementary research expertise.To effect optimal transfer of knowledge, the researchers will be embedded in to the collaborative research projects designed to:- Define membrane lipid map of blood cells of populations with a high intake of omega-6, omega-3 or saturated fatty acids to unravel the link between diets, membrane lipid and disease patterns;- Map blood cell membrane lipid of pregnant women with gestational diabetes and pregnancy-induced high blood pressure to examine a relationship between membrane lipid composition and the development of the diseases;- Elucidate the effect of dietary fat on membrane lipid map, signaling and gene and protein expression in cell culture and animal models of chronic diseases;- Understand the interaction between membrane lipids and amphiphilic psychotropic drugs.The added values will be- long-term link between the institution, and the researchers;- reduction of brain d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Uncovering the molecular and epigenetic mechanisms enabling corals to cope with climate change' (EPICORAL).

assistant: **Innovation**

At least 500 million people and >25% of all marine species directly rely on coral reefs – an ecosystem valued at $9.9 trillion annually, but one that is predicted to decline 70-90% by 2050 due to global climate threats. In addition to reef adaptation strategies, targeted approaches to enhance coral acclimation are critical for the persistence of reefs under future climate change scenarios. Yet, the molecular mechanisms underpinning acclimation in corals remain unclear, hindering the development of new restoration technologies. Environmentally sensitive epigenetic modifications, such as DNA methylation, are important molecular mediators of acclimation in many species. However, in corals, it remains unclear how DNA methylation is linked to climate resilience. With the support of the Marie Skłodowska-Curie Actions programme, EPICORAL will test a new, integrative and mechanistic hypothesis: that DNA methylation mediates coral climate resilience by maintaining transcriptional fidelity under stressful conditions. EPICORAL will take a multidisciplinary approach, building on complementary areas of expertise in marine ecology, genomics, epigenetics and transcriptomics to leverage a unique, in-situ experiment in a semi enclosed lagoon (where corals are long-term acclimatized to acidification, deoxygenation and thermal stress), and at a nearby control reef (where conditions are more benign). EPICORAL aims to elucidate previously unexplained scientific findings through high level training and knowledge transfer. By uncovering the role DNA methylation plays in coral climate resilience, EPICORAL will help to validate reef restoration approaches relying on the concept of “epigenetic conditioning” and provide early indications of coral stress-exposure through the development of “epigen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'OpenFlow Experiment in Real-Time Internet Edutainment' (OFERTIE), addressing dissemination and exploitation.

assistant: **Impact**

This Future Internet Research Experiment addresses an important emerging class of distributed applications known as Real-Time Online Interactive Applications (ROIA). These include multi-player online computer games, advanced simulation-based e-Learning and training platforms, and other applications dependent upon synchronised bidirectional media distribution. These applications are computationally intensive and typically cloud-hosted, and place heavy demands on the network. The loads are also highly variable, depending on the popularity of an application and the behaviour of participants.it is possible to use SLA-based management of cloud hosting across multiple data centres to scale and load balance applications dynamically and securely, while reducing start-up costs. However, network bottlenecks are introduced which limit scalability and quality of experience.Today there is no effective means whereby an application can manage the network over which it runs, such that business conflicts can be resolved when the application is distributed across multiple data centres and/or accessed via multiple ISPs, providing a mutually acceptable balance between the needs of ISPs, application providers, network providers and users such that users' expectations of performance can be met economically and sustainably for all service providers.OFERTIE will extend SLA-based management and APIs, integrating with OpenFlow, the programmable networking technology under-pinning the OFELIA experimental facility. The enhanced SLA-based management system will be used to control the use of computational resources by application processes running at each OFELIA site, and use OpenFlow to control routing decisions at each network switch. We will work with the OFELIA Testbed to run experiments to esta
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Scientific UV data management', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The overall goal is to initiate a scientific interpretation of the existing ground-based spectral UV measurements in Europe on the basis of an improved understanding of the radiative transfer processes. This will be realised by means of close interactions between the modelling and the measuring scientific communities by comparing the results of improved radiative transfer modelling calculations with quality-controlled UV measurements performed by stationary instruments at various sites in Europe. The following objectives will be addresses in this project: - to improve the existing radiative transfer models especially in cloudy and variable sky conditions. - to develop the scientific tools to be able to offer valuable responses to specific user's questions such as validity of geographically interpolated UV measurements, trends of biologically weighted UV, daily UV-doses, seasonal variations, etc. - to define the scientific tools and procedures for establishing an experimental 'database' for measured spectral UV-irradiance in Europe. - to define the type and the procedures for ancillary measurements and to continue the implementation of the quality-assurance and quality-control procedures.The SUVDAMA project combines the best available scientific resources in Europe to describe the actual UV  radiation. The obtained results provide a basis for future scientific research as well as for policy makers. The  final products of this programme will be an accessible data base including ground based spectral solar UV  irradiance measurements as well as ancillary measurements. This will be a very attractive tool for all scientists  involved in UB-B effect studies. The improved understanding of the radiative transfer processes obtained by  means of the modelling studies planned duri