RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Product and Process Design for AmI Supported Energy Efficient Manufacturing Installations' to be submitted under Seventh Framework.

assistant: **Abstract**

The aim is to enhance existing product/process design systems with features that will enable engineers to collaboratively design energy efficient and ecologically optimal discrete manufacturing processes, and generate appropriate extended monitoring and decision making services to support manufacturing installations to ensure optimal ecological impact over the process life cycle.Industrial companies have invested resources to make their products as energy efficient as possible. There is a lack of ICT systems/tools to support product/process design for energy efficiency of installations.A critical issue in energy use optimisation of manufacturing processes is availability of knowledge on actual energy consumption patterns within such processes. Ambient Intelligent (AmI) systems integrated in manufacturing installations may support energy efficiency of processes through extended services and provide such knowledge to optimise process design from energy efficiency point of view.A generic methodology and SOA-based context-sensitive services which can be easily added/integrated in the existing design systems will be developed: Energy Dependency Selector – pre-design stage planning of which equipment to use for meeting both specs and energy efficiency over the process life cycle for Eco-Design by applying TRIZ methodology, Energy Monitoring Setup – design of AmI systems and extended services to ensure energy efficiency of the installed process, Energy Analyser – multi-factor and multivariable optimisation of energy efficiency of process, Energy Simulator – what-if life cycle scenarios with stochastic inputs simulated to quantify the effects of different configurations.3 existing product/process design systems will be enhanced with these generic SW services and such integrated
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'ENERGY EFFICIENT URBAN SPORTS FACILITIES IN ECONOMICALLY DEPRIVED EAST END OF LONDON', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

First of a phased development of 5 energy efficient sport's buildings for the London Borough of Tower Hamlets, one of the most deprived local authorities in the U.K. Combination of features proposed for a 4713 sqm new multi-purpose sports hall, indoor tennis court and ancillary facilities. Limited measures planned also for existing facilities (1194 sqm). Advanced daylighting systems, ventilation recovery and energy efficient lighting and plant, improved insulation, natural ventilation enhancement through design, materials with low environmental impact. 54% savings compared to current construction and emission reduction.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Gene expression level as a keystone to understanding gene duplication: evolutionary constraints, opportunities, and disease' in the context of a Horizon 2020 call.

assistant: **Objectives**

Duplicate genes are important in disease, are a hugely important source of evolutionary novelty, and for many years we thought we understood them. We thought that duplication relieved selective constraints. We thought that gene knockout neutrality was due to redundancy. We thought that a duplicate is a duplicate is a duplicate. Evidence is accumulating challenging each of these views. Rather than being the result of an unbiased process, the genes that tend to duplicate in our genome and others are quickly evolving, non-essential genes, irrespective of current duplication status. Conversely, genes retained after whole genome duplication (WGD) are slowly evolving, important genes. I propose that different resolution of the evolutionary constraints imposed by the demands of gene expression can explain these contrasting relationships. I propose that the opposing constraints on gene-by-gene duplications as compared to WGD channel these different sets of genes into remarkably different evolutionary trajectories. In particular, in much the same way that individual gene duplication creates an opportunity for the evolution of a new gene, the co-evolution of expression of sets of interacting genes after WGD creates an opportunity for the evolution of new biochemical pathways and protein complexes. Furthermore, I suggest a common mechanism of pathogenicity for many duplication events independent of the biochemical function of the encoded genes.With the availability of abundant high-quality genomics data, now is an opportune time to address these questions. Primarily through computational and statistical analysis I will reveal the relationship between gene duplication and expression and test a model that the indirect costs of gene expression are a major determinant of the outcome o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Grasp-Related Neuronal Activity in Monkey and Human and Its Applicability in BMI' under Seventh Framework.

assistant: **Concept**

The complexity and precision of human hand control is staggering and unravelled, yet, its neuronal control is not well understood. Loss of this ability has devastating consequences for a human’s daily life. Restoring this ability and, thus, bringing relief to the patient’s condition should be an important aim of science.We propose an interdisciplinary investigation of both the neuronal activity controlling skilled hand movements and how this activity can be used in a Brain-Machine Interface (BMI) to control hand postures suitable for grasp of different everyday objects. For example, relevant patients rank the loss of skilled grasp as one of the most debilitating features of their injury (Anderson, 2004). Thus, grasp BMIs are of great importance, but not yet available.We will investigate grasp-related neuronal activity in monkeys and human volunteers based on recordings of (i) intracortical single-unit activity (SUA) and local field potentials (LFP) through multiple electrodes in monkey primary motor cortex (M1), ventral pre-motor cortex (PMv) and boundary areas between M1 and PMv, and (ii) non-invasive human magnetoencephalograms (MEG).Recent studies have shown grasp-specific neuronal activity in SUA and LFP recorded in monkey. We will record grasp-related activity simultaneously at various sites ranging from PMv to M1. Central points are the investigation of the spatial distribution of this activity across motor areas and different cortical laminae, the long-term stability and how this activity is modulated by novel motor tasks. We will also assess how these points affect the decoding of different grasps in a potential BMI and whether human MEG shows similar grasp specificity during execution and imagination of grasp, which is significant for patients controlling a BMI
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Application of new technology to increase access to the cultural heritage of St Albans' (CHOSA) targeting Fifth Framework.

assistant: **Abstract**

1) To improve access to the Roman town of Verulamium, in particular by young people, tourists and educational organisations2) To increase visitors to both Verulamium Museum and the Museum of St Albans3) To increase visitor satisfaction levels with their visit to Verulamium museum and the site of the Roman town4) To deliver a leading edge WAP solution that exploits and extends boundaries of the best available wireless technologyWork description:The project aims to increase access to the heritage of St Albans by guiding people around the roman remains in Verulamium park and by providing an exciting internet game that will appeal to younger people who don't like visiting museums or who can't get into the museum.The game will use the new Flash 5 application to turn a board game principle into interactive and educational fun. It is based on the bloody events and the people of historic St Albans.The guided tour uses cutting edge wireless technology, including GIS links, to feed a text and/or an audio tour (with graphics and video clips) into the new WAP phones allowing people to roam around the park experiencing far more of the roman town. Previous visitor surveys have demonstrated a visitor need for help in understanding the roman remains that lie outside Verulamium museum.Milestones:1) All participants agreed on what they are doing - Briefing documents2) Tour and game written - Copy3) Development of prototypes - Prototypes4) Usability and Staff training - Feedback5) Marketing plans - Promotion of project started6) Dissemination plans - Exploitation of project started7) Measurement - Evaluation of results availableOne computer game, with 5 sectionsTour of Verulamium Park for WAP phones, with added features: events diary, location of local facilities.Tour of Verulamium Park f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Improved printing process by electronically controlled adjustment of printing roller' (1994-1998).

assistant: **Concept**

At least 90 % of the SMEs in the printing industry in Europe use a technique where printing is carried out by using four different rollers and colours to create a print. The problem of the printing process of today is that it takes too long to adjust a machine when changing a printing pattern (or roller). The machine is normally running during two to four hours, after which the pressure is changed. This leads to a four to eight hours standstill. The cost of this standstill is well known. Merely within the gift wrapping paper industry, in Sweden, it is estimated that over 200 MECU could be saved per year if the stand still in production could be reduced or eliminated. In Europe the savings would arnount to approxirnately 3000 MECU per year.  The purpose of this project is to radically increase productivity and decrease pollution that is a result from the traditional printing process used by SMEs today. This will be achieved by developing a technique of electronically controlled adjustrnent of printing rollers.  By using a technology which is completely new to the printing industry, the availability of the printing line will be increased by at least 50 % and environrnental pollution will be substantially reduced. - The time it takes to charge a printing pattern will be drastically shortened ( 99 %). - The need for changing and cleaning the dye containers and the printing rollers due to change of printing pattern will be eliminated (100 %).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Effects of temperature, dynamics, and media on magnetic resonance parameters in endohedral fullerenes and confined Xe atom systems'.

assistant: **Concept**

Proposal concentrates on applying and testing computational methodology for accurate calculations of magnetic resonance parameters with inclusion of the relevant physical effects, such as electron correlation, relativity, dynamics, temperature, and media effects, in the calculation. This will be done by combination of the electronic structure theory methods with the simulation approaches, such as molecular dynamics and Monte-Carlo methods in a multiscale fashion. We will try to overcome drawbacks of current density functional approaches using and testing the new family of local hybrid functionals. We will apply and test novel, recently developed approaches for treating the relativistic effects. The methods will be applied to and tested on endohedral fullerenes and confined Xe atom guest systems. These two classes of very dynamical systems represent very multidisciplinary fields crossing the chemistry, physics, medicine, materials science, biology, and other disciplines. We will concentrate on current experimental questions and problems. Our aim is to provide answers to current hot questions in the field of endohedral fullerenes and confined Xe systems via reliable computational modelling to gain new understanding and stimulate new experiment, while pushing the state-of-the-art computational methodology forward.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'How do drug-associated contexts drive behaviour?  The role of entorhinal circuitry in addiction'.

assistant: **Concept**

Addiction to drugs is a ubiquitous neuropathological disease that inflicts immense societal costs. A core aspect of addiction that poses a major challenge for treatment is the propensity to relapse in environmental contexts that are associated with drug use. Identification and mechanistic characterization of novel addiction-relevant circuitry linking the motivation to take drugs to the complex spatial and non-spatial features that constitute a drug-associated context are at the core of this proposal. These insights will be used to identify the best constellation of anatomical targets to prevent and reverse the expression of context-triggered drug-seeking. The medial and lateral entorhinal cortex (MEC and LEC) are two central components of the episodic memory system integrating all features relevant for the formation of contextual memory. Crucially, MEC and LEC receive strong bottom-up dopaminergic input from the midbrain and send top-down projections to the nucleus accumbens (NAc). The dopaminergic system is the primary target of all addictive drugs. We will 1) study how bottom-up dopaminergic projections are implemented into drug-context associations in MEC and LEC and 2) determine how these associations influence NAc-mediated drug-seeking behaviour. We will utilize a multidisciplinary approach by developing electrophysiological in vivo recording paradigms in behaving mice that allow the assessment of complex spatial, contextual and non-spatial codes in conditioned place preference and self-administration paradigms typically used to model addiction in rodents. This will be combined with optogenetically-assisted circuit analysis of molecularly-defined pathways to link identified functions to the underlying circuitry. Pathway-specific optogenetic silencing will be used t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Nano-particle products from new mineral resources in Europe' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The objectives of the ProMine IP address the Commission’s concerns over the annual 11 billion € trade deficit in metal and mineral imports. Europe has to enhance the efficiency of its overall production chain putting higher quality and added value products on the market. ProMine focuses on two parts of this chain, targeting extractive and end-user industries.  Upstream, the first ever Pan-EU GIS based mineral resource and advanced modelling system for the extractive industry will be created, showing known and predicted, metallic and non-metallic mineral occurrences across the EU.  Detailed 4D computer models will be produced for four metalliferous regions. Upstream work will also include demonstrating the reliability of new (Bio)technologies for an ecoefficient production of strategic metals, driven by the creation of on-site added value and the identification of specific needs of potential end-users.  Downstream, a new strategy will be developed for the European extractive industry which looks not only at increasing production but also at delivering high value, tailored nano-products which will form the new raw materials for the manufacturing industry. ProMine research will focus on five nano-products, (Conductive metal (Cu, Ag, Au) fibres, rhenium and rhenium alloy powders, nano-silica, iron oxyhydroxysulphate and new nano-particle based coatings for printing paper), which will have a major impact on the economic viability of the extractive industry. They will be tested at bench scale, and a number selected for development to pilot scale where larger samples can be provided for characterisation and testing by end-user industries. It will include production, testing and evaluation of these materials, with economic evaluation, life cycle cost analysis, and environmental
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Rapid development and distribution of statistical tools for high-throughput sequencing data'.

assistant: **Objectives**

High-throughput sequencing (HTS) is a powerful and rapidly evolving family of technologies with a multitude of applications. They include genetics of rare and common diseases, understanding of disease mechanism and progression through transcriptome and epigenome profiling, cancer stratification, personalised medicine and molecular systems biology of gene regulation. The genome, epigenome, transcriptome and interactome are all intricately connected, and modern HTS technology can probe all of these -omic levels. Statistical analysis is a crucial component of many experiments and studies, and the quality and efficiency of the analysis often determines the success of a project.In this collaborative project we will develop a range of new statistical analysis tools to solve open problems in HTS data analysis, ranging from low-level processing of sequence reads up to systems-level modelling of disease associated and cellular processes. We will provide to a wide audience an integrated computational framework for HTS data analysis and interpretation that is robust, efficient and user-friendly. We will establish improved procedures for the publishing of statistical software as an integral part of the scientific publication process, within the framework of the Bioconductor project. We will provide tools to benchmark experimental protocols and statistical methods, and we will provide training materials and a extensive training programme to rapidly disseminate these new tools to the broader biomedical community.SME partners will integrate these new tools within their analysis pipelines with associated user-friendly commercial software providing access to their additional proprietary tools. SMEs will benefit from basic methodology development done in a public, pre-competitive arena a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Shifting to a Land Systems Paradigm in Conservation'.

assistant: **Objectives**

Biodiversity loss is a global crisis threatening human wellbeing, and the main driver is how we use land. Decisions about land use are made in social-ecological systems, yet conservation science is currently ill-equipped to consider the complex and dynamic interactions between land-use actors and their environment. This translates into conservation failures and missed opportunities. My overarching goal is to develop new, interdisciplinary concepts and approaches that enable a different, social-ecological perspective on land use in conservation. This promises major breakthroughs in our understanding of threats to biodiversity and how to design effective conservation strategies. My project will be organized in three main steps. STEP 1 will develop novel concepts to identify key combinations of land-use actors, practices, and threats to biodiversity, and organize them into a systems typology for conservation. This step will also design innovative indicators to map how threats vary and interact in space and time. I will apply and test these concepts globally, for the poorly studied tropical dry forests. STEP 2 will empirically validate these concepts for two tropical dry forests regions in South America. Comparative social-ecological fieldwork will reveal how threats impact biodiversity, how land-use actors relate to threats, and how conservation actions influence actors. This will enable a major advance in conservation planning methods to consider land-use actors, dynamic threats, and to rigorously evaluate when, where, and at which scale conservation is most effective. STEP 3 will integrate the project results to provide generalized insights into conservation challenges and opportunities in tropical dry forests globally. My project will cross-fertilise between land system