RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Home2nite is an innovative guest engagement platform that aims to empower the independent hotels as AirBnb did for the travel hosts.' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

AirBnb has disrupted the travel industry by empowering ordinary people. Those ordinary people became the biggest hotel group in the world with 2.3 million rooms - Marriott group, which has recently acquired Starwood Hotels, could only became the second with 1.1 million rooms. [i]AirBnb has not acquired 18% penetration in the market just providing a marketplace with a fancy mobile app and web site, but advice and services to help its providers with their business efforts e.g. sending a professional photographer to get the best images captured or reporting the pricing of competition per neighbourhood, per seasonality etc. to let the provider set the right price. Airbnb helped these people with their business and their engagement with the guests. Then became a $30 billion company[ii] helping its providers make $12.3 billion each year.[iii]“Airbnb for the Hotel Industry” would be an appropriate analogy for Home2nite.Independent hotels in EU represent 67% of the room supply counting for more than €35 billion [8] economic value for the region. Most of them are family run businesses, which reflect the Europe’s cultural heritage, past and social diversity. They are not well aware of  how to exploit the technology to attract more customers, increase engagement with them and improve operational efficiency along with customer satisfaction. Without these skills, they are under serious trouble, even if some of them don’t see it now.Home2nite’s ambition is helping independent hotels with the tools and skills they need for survival under the fierce competition from global chain hotels and Airbnb providers. Our target is preserving the economic value they represent for EU, protecting the jobs they created and last, but not the least, continue to see them reflecting the Europe’s cultura
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Unraveling Principles of PDZ-mediated Cell Signaling'.

assistant: **Concept**

PDZnet will create an innovative European PhD training network focusing on unraveling PDZ domain-mediated signaling networks. The emphasis will be on signaling nodes essential for the development of cancer and diseases of the nervous system, conditions that affect millions of Europeans and are major societal challenges. PDZ domains are protein and lipid recognizing modules that play a central role in trafficking and organizing diverse cell signaling assemblies, thereby allowing information to be transmitted from receptors, ion channels and transporters in the cell membrane. PDZ domain mediated interactions are emerging as conceptually novel and promising drug targets, with exciting opportunities for the development of novel therapies, especially within cancer and brain diseases. We will establish a European multidisciplinary platform integrating a plethora of complementary life science disciplines that range from chemical development of inhibitors to studies in live animals. The network encompasses 8 academic and 2 industrial beneficiaries as well as one industrial and one academic partner, which are all committed to promote frontline research, innovation and educational activities within the study of PDZ domain-mediated signal transduction pathways related to brain diseases and cancer. This interdisciplinary network will establish an outstanding training opportunity for Early Stage Researchers, who will be integrated in projects unraveling intracellular PDZ domain interactomes to provide pertinent information for discovering drug-related interactions. In a comprehensive and integrated training effort, involving a combination of scientific and transferable skills, the students will receive an interdisciplinary, intersectoral and innovative doctoral training from experie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Centre for Applied Creative Technologies' to be submitted under Horizon 2020.

assistant: **Abstract**

Bournemouth University (BU) will host CfACTs as a MSCA COFUND research training centre for experienced researchers (ERs), providing the international mobility and cross-sectoral experience through the well-aligned training and research programme. With the ERs research and innovation development on their chosen topics, it will bring significant change to the technological landscape by adopting novel creative technologies into various applications to promote well-beings and innovations. CfACTs will operate from 1 Oct 2020 to 30 Sep 2025to host 6 MSCA ERs (CfACTs ERs hereon). These CfACTs ERs will be recruited in two cohorts during the period 2020 to 2023.The 6 CfACTs ERs will be full-time academic employees of BU, and embark on a two year programme of world leading digital creative technology research and training provided by CfACTs, and its Partner Organisations (POs, e.g. Sony, Emteq).  Each CfACTs ER will have an opportunity to be seconded into one or more POs for the majority of their two year programme with full academic support to gain cross-sectoral experience. The CfACTs ERs will research and develop new applied digital creative techniques, collaboratively with industry POs; and apply them cross-sectorally for various applications including but not limited to, computer animation, visual effects (VFX), computer vision, visualisation, healthcare, retail and assistive technology. These new techniques will also bring important productivity improvements to many industries. The BU academic expertise underpinning CfACTs is sourced from BUs world-class National Centre for Computer Animation (NCCA) and as required, other BU centres of research excellence, including: Centre for Games and Music Research; the Orthopaedic Research Institute; the Centre for Archaeology and Anth
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Resolving metabolic interactions between the gut microbiota and the host with multi-omics-based modelling' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The gut microbiota is essential to human health: microorganisms in the human body help to digest nutrients, engage in host metabolism, immunity, behaviour and brain functions. Since the gut microbiota, in contrast to the human genome, can be modified through dietary and therapeutic interventions, modulating the microbiota is a promising path to improve human health and to prevent or treat diseases. However, predicting the effects of microbiota perturbations on the host metabolic phenotype remains extremely challenging due to our limited understanding of bacterial metabolic functions, molecular interactions within microbial communities, and the mechanisms of microbial interactions with the host.I propose to tackle these challenges with a combination of experimental and computational approaches in a synthetic community of 14 common human gut bacteria, which has been associated with > 150 health-relevant metabolites involved in amino acid, vitamin, and hormone metabolism in vivo. We will follow a bottom-up strategy to i) systematically characterize the capacity of single bacteria to consume and produce metabolites of interest and identify the responsible enzymes; ii) investigate the metabolism of these compounds in compositionally diverse synthetic communities; and iii) quantify and modulate microbiota contribution to the host metabolism of these compounds in mouse models. To this aim, we will combine high-throughput bacterial culturing, metabolomics, transcriptomics and proteomics assays with genome-scale metabolic modelling, graph-based multi-omics integration methods and physiology-based models of microbiota-host interactions. This project will provide a generalized framework to systematically resolve microbiota contributions to the host metabolic phenotype, and elucida
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'COMRIS: co-habited mixed reality information spaces' (COMRIS) targeting Fourth Framework.

assistant: **Abstract**

The COMRIS project aims to develop, demonstrate and experimentally evaluate a scaleable approach to integrating the Inhabited Information Spaces schema with a concept of software agents. The COMRIS vision of co-habited mixed-reality information spaces emphasises the co-habitation of software and human agents in a pair of closely coupled spaces, a virtual and a real one. However, this project does not pursue the perceptual integration of real and virtual space into an augmented reality. Instead the coupling aims at focusing the large potential for useful social interactions in each of the spaces, so that they become more manageable, goal-directed and effective.The COMRIS project uses the conference centre as the thematic space and concrete context of work. The conference centre is a structure of places for registration, presentation, refreshment, and so on. At a conference, like the Annual Esprit meeting in Brussels, people gather to show their results, see other interesting things, find interesting people, meet EU officials in person, or engage in any kind of discussion. The possibilities of interaction at such an event are enormous, it is very information-intensive, and the great diversity of topics and purposes that are being addressed make it difficult to get everything done. This clearly motivates our aim of focusing a large potential for interaction such that effectiveness of participation to such or another large event is enhanced.In the mixed-reality conference centre real and virtual conference activities are going on in parallel. Each participant wears its personal assistant, an electronic badge and ear-phone device, wirelessly hooked into an Intranet. This personal assistant - the COMRIS parrot - realises a bi-directional link between the real and virtual spac
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Functional Agricultural Biodiversity : Optimising ecosystem service provision via functional agricultural biodiversity' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Regulating services (pest regulation and pollination) are considered to be the major ecosystem services (ES) delivered by biodiversity to agriculture worldwide. Unfortunately the expansion of modern, chemical-intensive agriculture has caused widespread declines in the abundance and diversity of beneficial arthropods (e.g. bees, natural enemies of pests) and the valuable ES they provide. Increasing plant biodiversity to enhance pollinators and natural enemies in agro-ecosystems is a promising management technique to foster ES delivery. However, the translation of increased species diversity and abundance into enhanced ES provision and thus crop yield cannot be depended upon. Furthermore, ES are currently studied in isolation and potential antagonisms between ES poorly understood. With recent research suggesting that management methods for one ES may be detrimental to the other, it is imperative that these ES are no longer studied in isolation to better understand potential antagonisms / synergies. The FAB (Functional Agricultural Biodiversity) Project will, for the first time, study the effects of plant biodiversity on the delivery of these two vital ES collectively. Performed in collaboration with ECOBIO and the company Yves Rocher, the project will utilise cereal and flower fields in NW France to investigate the spatial and temporal distribution patterns of key ES-provider species and how this translates into increased ES provision (pollination and pest regulation for the farmer). Ultimately, the research aims to find solutions for the removal of barriers that prevent or limit the delivery of pest regulation and pollination by FAB and ES management strategies and enhance yield for the farmers. A 6 months secondment to Yves Rocher will offer me unique insight into indus
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'New Algorithms for Host Pathogen Systems Biology' (SYSPATHO).

assistant: **Innovation**

SYSPATHO focuses on the development of novel and generally applicable mathematical methods and algorithms for systems biology. These methods and algorithms will be applied to study the complex interactions of hepatitis C virus (HCV), a human-pathogenic virus of high medical relevance, with its host at the systems level. Using a multidisciplinary, integrative approach, PATHOSYS will (a) develop methods to analyze and integrate a wide variety of data from wet lab experiments, databases and biological literature, (b) develop and apply machine learning tools to reconstruct and study intracellular interaction networks from experimental data, (c) develop new and improve existing algorithms and mathematical methods for bottom-up modelling, to fit models to data, and to analyze the dynamic behaviour of models (d) generate new experimental data to gain novel insights into hepatitis C virus host interactions, and (e) use the newly developed methods and data to model and analyze HCV-host interactions at the systems level. Guided by biological data, PATHOSYS focuses on the design of novel algorithms and mathematical methods for systems biology, with the aim to provide generally applicable tools to elucidate biological processes. Based on developed models and using systems analysis, PATHOSYS will elucidate virus host interactions of Hepatitis C virus at an unprecedented level. As a direct spin-off, models and analysis methods developed in PATHOSYS will lead to the identification of new candidate host cell target genes applicable for the design of novel anti-viral drugs against hepatitis C. Targeting of host cell factors will reduce the likelihood for the development of therapy resistance and increase the chance for broad-spectrum antivirals. Inclusion of two SME partners will ensure
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Transforming single-molecule mass measurement by rotating total internal reflection mass photometry'.

assistant: **Concept**

We aim to develop a novel label-free optical microscopy approach to transform our ability to characterize and quantify biomolecular dynamics and interactions at the single small-molecule level. The core of the technology, termed rotating total internal reflection mass photometry (RoMP), rests on delivering a step change in label-free detection and quantification of light scattering from individual biomolecules in solution. We will achieve this by leveraging the advantages of total internal reflection to boost optical contrast, and suppress background signatures. This will be enabled for the first time in the context of interferometric microscopy through the use of a specifically-designed optical attenuation optic. Compared to the state-of-the-art Mass Photometry (MP), RoMP will transform the quantitative detection limit and improve mass resolution from ~50 kDa to 10 kDa and from 20 kDa to 2 kDa, respectively. These advances will dramatically expand the range and identity of studies that can be performed by single molecule mass measurement, representing an advance comparable to the change in resolution from 15 to 1.5 Angstrom in cryo-electron microscopy over the past decade. The interdisciplinary and complementary aspects foster two-way transfer of optical nano-imaging knowledge between the applicant (illumination-modulated fluorescence microscopy) and the host (detection-modulated label-free mass microscopy), ultimately catalyzing innovative biochemical investigations and their application by a broad user base for maximum impact.


**Keywords:** Single-molecule mass imaging, Mass photometry, Interferometric scattering microscopy, Label-free optical microscopy, Total internal reflection
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Ichnological analysis of core and outcrop contourite facies: scientific and economic implications' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Deep water dynamic causes different types of currents which produce complex deposits called in general terms as contourites. These deposits have a high interest in palaeoenvironment, palaeoceanography and hydrocarbon exploration being considered as a hot topic with scientific and economic implications. In spite of numerous studies they are still poorly understood and there are some controversial points about their recognition.Deep-water currents are associated to notable changes in environmental parameters influenced by ocean/atmosphere dynamic and palaeoclimatic variations. In this sense, the study of contourites provides information to interpret palaeoenvironmental changes and associated processes. Moreover, contourites have an economic importance, associated to hydrocarbon exploration, in relation to reservoir quality, store and seal rock distribution.Bioturbation was firstly considered as a diagnostic criterion as contourites and mixed systems have significant macrobenthic trace-makers activity. During the last years, ichnological analysis has suffered a huge development being one of the most used proxies in sedimentary basin to interpret palaeoenvironmental conditions and ocean/atmosphere dynamic. Moreover, analysis of bioturbation is also interesting for hydrocarbon exploration as trace fossils can modify porosity and permeability of sediments affecting the potential reservoir quality.Therefore, considering the scarcity of ichnological studies in contourites, but evidencing the importance of bioturbation as a potential diagnostic criterion, the influence in porosity and permeability values and its economic interest, the present proposal will be focused, for the first time, on the detailed ichnological analysis of these deposits, with two main objectives: firstly,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'In situ deformation experiments to study ductile strain localization' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Plate tectonics, by linking the evolution of the Earth’s surface to the dynamics of the deep interior, has provided a coherent framework to understand the formation of mountain ranges and oil-rich sedimentary basins, as well as the distribution of major catastrophic events such as volcanic eruptions and earthquakes. We now understand that it is an essential and unique feature of mantle convection but the processes behind still remain a major open question. Strain localization at the plate scale is crucial for the generation of plate tectonics from a convecting mantle but, while in the brittle field (producing faults) it is a well-known process, in the ductile regime –within 5/6 of the plates– it is still poorly understood. The most enigmatic point is the initiation of strain localization in a homogeneous and isotropic medium. How the deformation itself produces a heterogeneous weakening leading to localization: is it driven by shear heating or grain size reduction? Detailed microstructural observations on naturally-deformed rocks and existing laboratory experiments did not allow quantifying the processes that occur during plastic deformation thus the initiation of strain localization is still under debate. In this project we propose to obtain this data, which is essential for understanding and modeling strain localization due to microstructural evolution, via in situ experiments in SEM dedicated to the measurement of crystal orientations by indexation of EBSD patterns allowing for high-resolution characterization of the microstructural evolution during deformation. The proposed experiments will be performed on polycrystalline ice and magnesium, which (1) deform ductilely in the PT range of experimental conditions applicable in the SEM-EBSD, and (2) show strong anisotrop