RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Breakthrough Fuel Cell Technologies for Aviation' (BRAVA) under Horizon Europe.

assistant: **Objectives**

The Proton Exchange Membrane Fuel Cell technology emerging from the automotive industry is of high interest for the future aeronautic industry. While automotive industry fuel cell (FC) systems are usually limited to 100 kW, aircraft require a significantly greater amount of power (multi-MW) and must operate at both different temperatures and pressures, while keeping the system’s safety and reliability levels to aeronautical standards.BRAVA will develop breakthrough technologies for a FC-based Power Generation System (PGS) for aviation. The overall target is a high-performance PGS with a power range of over 2 MW. The foreseen future multi-MW system will be a multi-stack aircraft propulsion system. Airbus reckons that several of such multi-MW FC-based PGSs can be used to propel an aircraft capable of carrying up to 100 passengers on distances of up to 1,000 nautical miles. Advances in the FC stack and balance of plant components, the thermal management system, heat exchanger design and technology, and air supply system architecture, will act as building blocks for this multi-MW FC-based PGS. The key project results are:•New catalysts and membranes with higher performance, durability and higher operating temperature capability to enable integration into new Membrane Electrode Assemblies to reach high efficiency, low weight, compactness and long lifetime; •2-Phase cooling based thermal management system (including a newly designed fuel cell stack) for compactness, weight reduction and hence improved fuel consumption;•Additive manufactured heat exchangers for increased heat rejection, compactness, lightweight and low drag;•A new air supply architecture and components designed and optimized to provide low parasitic power and weight reduction and thus enabling lower fuel consu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Environmental crimes’ intelligence and investigation protocol based on multiple data sources', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The aim of the EMERITUS project is to realize and implement a protocol for effective environmental crime investigation, leveraging on the integration of innovative monitoring and analysis technologies (drones, satellite data, virtual sensors, geo-intelligence data, etc.), and on a complementary training programme aimed at fostering environmental enforcement authorities (e.g. Police Authorities and Border Guards Authorities) intelligence and investigation capabilities, at national and cross-border level. In order to achieve this goal, the EMERITUS consortium has gathered 8 Police/Border Guard authorities from 5 countries, 4 security experts, 2 training specialists and 6 technological partners, that will be the core of the platform.The consortium will focus on the co-creation of an investigation protocol centered on environmental crimes investigation, that will orient to the creation of the geo-intelligence platform. This platform will integrate several monitoring and investigation technologies and data sources, in a single view to support Police Authorities and decision-makers. Secondly, a new training programme for Police Authorities and other security practitioners, focused on environmental (waste-related) crimes investigation and prevention, will be delivered combining both theoretical aspects and hand-on simulations to empower end-users to actually use the platform and related technologies. Such exercises will serve to validate both the platform and the protocol, via simulations based on 4 realistic use cases (heterogeneous and of growing complexity), taking advantage of the shared will of Police Authorities and Border Guards to focus on ad hoc demonstration sites, with the additional availability of partners’ simulation facilities. The validation of the platform and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Biophysical mechanisms regulating early T cell signalling events' (BIOPHIS).

assistant: **Concept**

The overall aim of this project is to identify key biophysical mechanisms that control the spatial arrangement of signalling proteins and membrane lipids in the regulation of T cell receptor (TCR) activation. During an immune response, T cells are activated in response to antigenic peptides in a process that requires the formation of multi-molecular signalling complexes. It is known that many T cell signalling proteins (such as the kinase Lck and the scaffold protein LAT) are not randomly distributed within the plasma membrane thus giving rise to lateral organizstion which affects signalling efficiency. However, the biophysical mechanism(s) that control protein distributions and hence the rate of molecular interactions remains poorly understood. Uniquely, I have recently developed two key technologies to unravel how protein clustering and the biophysical properties of the lipid bilayer regulate specific interactions at the molecular level. These are single-molecule, super-resolution localisation microscopy with novel statistical cluster analysis and quantification of membrane biophysical properties beyond the limit of conventional microscopy using new environmentally sensitive fluorescent probes and picosecond time-resolved excitation/detection. The research will therefore generate unique insights into the biophysical mechanisms that govern the formation of the protein clusters and complexes during early T cell signalling events. This knowledge is critical to our understanding of the molecular basis of T cell activation during the immune response and has potential applications in the development of therapeutic treatments for a range of conditions including pathogenic disease, cancer and autoimmune disease.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The Intelligent Autonomous Microscope: An AI platform for multiplex parasite diagnosis at the point of care' under Horizon Europe.

assistant: **Concept**

A new generation of diagnostic systems available at the point of care (POC) could save lives and reduce the spread of infectious diseases worldwide through early detection and treatment. Optical microscopy remains the gold standard for the diagnosis of many parasitological diseases; however, its accuracy is dependent on the availability and expertise of the analyst at the POC. This limitation is increased by the dependence on labour-intensive examination processes, lack of standardization, high interobserver variability, insufficient precision in sample quantification and, as a consequence, a high misdiagnosis rate. This project introduces an AI diagnostic system leveraging existing microscopes and mobile technology providing a comprehensive and holistic sample analysis rather than just detecting individual pathogens. MultiplexAI is a scalable, low-cost, autonomous AI diagnostic system for the POC that upgrades any optical microscope into an AI agent able to accurately identify any parasite in a sample.  We will collect data, train, deploy and evaluate the integrated system to detect multiple diseases including malaria and parasitic Neglected Tropical Diseases. The project will pursue the following objectives and methodological steps: 1) To design a trustworthy AI system, ensuring technical and social robustness, and adherence to WHO AI ethical principles of safety, transparency, explainability, accountability, equity, and sustainability; 2) To develop AI foundational models for microscopy analysis capable of automating the detection, differentiation and quantification of multiple parasites causing disease and integrate them into an automatic mobile microscopy system; 3) To validate the system in laboratory settings; 4) To undertake a performance evaluation study in cli
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'PRoteome-based assessment of vascular disease for the Establishment of a Translational REsearch plATform'.

assistant: **Innovation**

Cardiovascular disease (VD) is the leading cause of mortality and morbidity in Europe and worldwide. The objective of the PRETREAT consortium is to generate a joint SME/academic European preclinical platform for providing services for detection of VD and drug development. This platform will combine the use of urinary and/or blood peptidomics in humans and in preclinical animal models of VD, together with bioinformatics and systems biology, in order to better detect, stratify and decipher the molecular mechanisms of VD, develop new animal models with high similarity to human disease, and provide new tools for obtaining information on novel drug targets.PRETREAT builds on the FP7 project Sysvasc (systems biology to identify molecular targets for vascular disease treatment, 2014-2018) and the combined expertise of the PRETREAT partners in clinical proteomics, proteomics, animal models and system medicine as the pillars to implement this platform. The work will be carried out in an extensive exchange program totaling 27 secondments. Main objectives during the secondments include establishment of the link between urinary markers and the pathophysiology of VD, identification of additional animal VD models with similarity to human VD, development of “humanized” body fluid readouts in VD models, establishment of a VD protein-centric database in order to automatically link urinary peptides to in situ changes and provide information on drug targets, and provide proof-of-concept of the utility of the proposed platform. These secondments will in parallel serve to keep information flowing within the project, increase individual research efficiency and create a multi-disciplinary working chain, train personnel, and prepare the sustainability of the results after the project. To compl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'a Framework for goal-Oriented Characterization of real-time reqUirementS in 6G networks: Driving convergence of the physical and digital worlds (FOCUS-6G)'.

assistant: **Concept**

FOCUS-6G’s objective is to power real-time applications in 6G by effectively driving the convergence of the physical and the digital world and thus enabling seamless real-time interactions. To this end, this project aims to develop a framework for goal-oriented characterization of real-time requirements and leverage it for designing optimal real-time transmission strategies, thereby making the network perceptive in nature. Pertinently, the project will effectuate a paradigm shift in how we approach and overcome the challenges of two critical aspects of the envisioned perceptive network: responsiveness of the network and the reliability of communication between its constituent elements. With repsect to responsiveness, moving beyond the current state-of-the-art, firstly, instead of assuming resource intensive ultra-stringent latency targets as the timing requirement; which will be ineffective for 6G applications; this project will parameterize real-time requirements based on the specific goals of the application. Secondly, the  project will incorporate timing elements associated with processing and computation operations, providing a comprehensive view of timing needs. Finally, the project will develop a framework to determine the temporal ordering (simultaneity and causality) of events reported by multiple devices, which will be crucial for ensuring network’s perceptivity and responsiveness. On the reliability front, firstly, the project will employ grant-free access protocols, allowing devices to transmit instantaneously. To manage the interference inherent in grant-free methods, rate-splitting multiple access (RSMA) mechanism will be innovatively leveraged to deal with the interference between multiple devices, and imperatively, between digital and sensing data. Subseq
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Energy supply chains design and management for higher efficiency and sustainable futire' (ESCHAINS) targeting Sixth Framework.

assistant: **Abstract**

The importance of energy is bound to the currently ongoing climate change, the availability, cost and the security of the energy supply - all of them being part of the concept of sustainable development. A key factor for achieving sustainability is the increased use of renewables, and lower CO2 emissions. Biomass and fuels derived from it are one of the promising alternatives.The main advances in the field include energy integration in industry and the design of Combined Heat and Power systems. This has been followed by extensive research on utilisation of renewables from which biomass is one of the most popular options. 'Energy Supply Chains Design and Management for Higher Efficiency and Sustainable Future' is an interdisciplinary project aimed at creating a strong team for research on energy/resource efficiency and sustainable development, led by the applicant. The research will be based on several key concepts. The recognition of the systems nature of energy has significantly increased in recent years, but it there is still lack of a well-established structuring paradigm.Life Cycle Analysis is a well-developed set of ideas and tools, many of which applied in the energy field. This will be used in order to model comprehensively the environmental, social and economic impacts of the energy solutions. LCA alone is not sufficient - problems stem from lack of appropriate data, and unclear system boundaries. To allow for clear definition of system boundaries LCA will be applied in the context of the combined energy-food-waste supply chains.The results from the project are expected to benefit commercial enterprises allowing them to evolve continuously towards increased share of renewable energy in most economic way. Policy makers will benefit from being able to better plan
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Clinical validation of the DiviTum assay in key European markets' (CVDTEU).

assistant: **Concept**

Many cancer therapies fail due to inadequate prediction of patient-specific treatment responses. In addition, a large number of clinical trials fail due to a lack of predictive tools for optimal cohort selection. Biovica has developed a sensitive and precise assay for the measurement of a biomarker thymidine kinase (TK) from serum as an indicator of cell proliferation. Our assay technology has been clinically tested and has demonstrated beyond state-of-the-art capability compared to existing solutions due to its unprecedented sensitivity. This allows for previously unrealized capabilities in monitoring and prediction of therapy response for most common cancers. The unique selling point of our technology is the documented ability to reliably measure solid tumor proliferation from serum, thereby making it cheaper, more scalable and less invasive for the patient than industry standards. Our key customers are drug developers and clinicians who will use it for optimal cohort selection for clinical trials, and prediction of treatment response for patients respectively. However, in order to reach these customers, we require carrying out extensive clinical validations to demonstrate technological soundness. Europe represents the largest market for biomarker diagnostics due to a growing ageing population. We therefore aim to conduct clinical studies in key European markets with access to relevant bio-banks. In phase 1 of the proposed project, we will perform a feasibility study with focus on market related activities in Europe. Thereafter we aim to conduct clinical studies in selected European countries in partnership with clinicians. Our ambition is to become the industry standard for cancer proliferation measurement worldwide.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Developing a scalable production route for functional high performance in-situ TEM cells'.

assistant: **Concept**

This project aims to revolutionize in-situ gas cell transmission electron microscopy (TEM) by scaling up the novel in-situ cells that have been pioneered in the EvoluTEM Starting grant. Traditional commercially available gas cells limit TEM imaging resolution and spectroscopy due to significant electron scattering. The EvoluTEM project has demonstrated a proof of principle cell design which reduces the electron scattering and hence provides opportunities for TEM experiments with greatly improved imaging of atomic structure and spectral analysis of local changes in oxidation state or elemental distribution. This research project will scale up the gas cell fabrication process, validating its performance in key applications and ensuring its compatibility with commercial TEM in-situ holder systems. The overall aim of this project is to provide the wider scientific and industrial TEM community with environmental cells that provide a step change in the performance of their existing in-situ technology. This will be vital for improved understanding of nanomaterials and catalysts under relevant environmental conditions, thereby accelerating the development of improved materials for applications such as sustainable energy generation, healthcare and new communication technologies.


**Keywords:** transmission electron microscopy, gas cell, in situ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Risk Management Software System for SMEs in the Construction Industry' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The construction sector is one of Europe's biggest industries accounting for 10% of Gross Domestic Product  with approximately 92% of manufacturers being SMEs. This sector directly employs 12 million EU citizens and 26 million workers are dependent on the sector. However, due to the global economic crisis, the last few years have been full of uncertainty for many companies in the construction and engineering industry.  These companies are facing fierce competition and winning new contracts as well as delivering on schedule and on budget is fundamental to their survival. Core to these problems are, enterprises and more especially SMEs are operating in a dynamic business environment with constant exposure to risk leading to underperformance, low productivity and sometimes businesses could stop trading overnight. This project therefore, aims at developing a cost effective, user friendly risk management system, which evaluates, monitors, and reviews both imminent and impending risks with a view to completely eliminate or minimise their impact.  RiMaCon consortium wishes to challenge and overcome the current non trivial, interdisciplinary and intersectoral barriers currently preventing the development and implementation of efficient risk management systems in SMEs. It will therefore design and develop a robust, reliable, and sustainable risk management prototype system suitable and affordable for the construction SMEs, possibly in a software format or a portal. This risk management prototype will be dynamic, flexible to adapt to different construction contexts. RiMaCon has already carried out preliminary survey / investigation and confirmed this need especially for SMEs who are under resourced, vulnerable and also lack the technology to develop a robust risk management syste