RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Growth in Groups and Graph Isomorphism Now'.

assistant: **Concept**

In recent years there has been spectacular progress in studying growth in groups. A central result in this new area, obtained by Pyber-Szabo' (with a similar result proved by Breuillard-Green-Tao), shows that powers of generating subsets of finite simple groups of ""bounded dimension"" grow fast. Extending this Product Theorem Szabo' and the PI also proved a weaker version of a conjecture of Helfgott-Lindenstrauss. The Product Theorem has deep consequences in the study of groups, number theory and random walks. A central open question of the area is to remove the dependence on dimension in our Product Theorem. The PI formulated a new Conjecture, as a step forward. The way to further progress is via combining techniques from asymptotic group theory and probability theory. It is from this perspective that the current GROGandGIN proposal addresses issues concerning random walks. We examine how recent probabilistic arguments for random walks in the symmetric group may be transferred to matrix groups. While the first results in the subject of growth concern matrix groups we see an evolving theory of growth in permutation groups. This relies on earlier work of Babai and the PI which aims at finding proofs which do not use the Classification of Finite Simple Groups (CFSG). Similarly, Babai's famous Quasipolynomial Graph Isomorphism Algorithm builds on ideas from CFSG-free proofs due to him. The PI has recently removed CFSG from the analysis of Babai's algorithm. Our method goes ""halfway"" towards removing CFSG from proofs of growth results for permutation groups, currently a major open problem. The GROGandGIN initiative plans to improve various other parts of Babai's paper, working with several people who look at it from different angles, with an eye towards obtaining a Polyn
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Photomechanical printing in Europe in the mid-19th century: History, theory, visual culture, science and the international network in the 1840s-1860s' (PHOTOMECHANICS), addressing dissemination and exploitation.

assistant: **Impact**

The project examines the pioneering era of photomechanical printing as a fundamental part of history of photography, art, science and modern visual culture. It focuses on the first three decades of development of photomechanical technologies, i.e. the era between the introduction of photography in the late 1830s and the outset of industrial mass-production of photography-based images in the 1860s. It centres on the UK, France and the Austrian Empire, as countries which played leading parts in the photomechanical research and practice from the 1840s onwards. Considering the state of the art of existing scholarship, as well as the amount and variety of preserved sources, the research will comprise collection and archival surveys, visual, material and contextual analysis and interpretation of original objects (prints and matrices), as well as close reading of correspondence, manuscripts and period publications. In order to understand the circumstances and cultural contexts in which different photomechanical technologies emerged and developed, the project will also look at social structures and networks of inventors, supporters, critics, and users. Great attention will be paid to theoretical period discussions on potential and the future of photomechanical printing. More elaborate knowledge of these phenomena will help to understand not only history of photography, but also history of art and science, and to consider more carefully different perspectives on development of photography-based technology and its interpretation. Through close collaboration with the supervisor and the partner institutions, the fellow will be able to extend her research beyond history of photography, and to enhance her complex research capacities, inter-sectoral collaboration, networking, leadersh
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Fiber Optic Sensors Application for Structural Health Monitoring' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The proposal is addressed to the exploitation of fiber optic based sensor for structural health monitoring of aeronautic structures and materials. The activity plan is organized in three tasks, according to the call description. The first activity will be focused on preliminary research on the use of Fiber Optic Bragg Grating (FOBG) sensors for the strain evaluation during a fatigue test on metallic samples in corrosive environment, with the aim to define and characterize a new experimental methodology capable to provide an innovative tool for the prediction of corrosion initiation. The second activity is addressed to the demonstration of a new approach for the realization and test of an apparatus for FOBG sensors interrogation. The task is motivated by the need to identify a robust and reliable instrumentation for flight test campaign. Starting from results of previous experimental campaign carried out together with Alenia, the actions to develop are devoted to the identification of a new class of commercial devices and/or systems for the integration of a novel instrumentation which should be qualified for flight test campaign and, at the same time, must provide higher performances than conventional equipments. The third research activity will be aimed to the development of a distributed strain and temperature sensing system based on standard optical fibers employment. The scattering effects (Raman, Brillouin, Rayleigh…) on the basis of this new technique will be analyzed and prototypal and commercial solution, already certified for laboratory application, will be evaluated. The distributed technique will be tested during ground test campaign, with the aim to reach performances comparable to these typical of FOBG based discrete sensing systems. In conclusion, the propo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'BRAIN organoids unTanglement with SERS'.

assistant: **Concept**

Neuropsychiatric disorders and neurological diseases have a devastating impact on patients’ lives and represent a heavy social and economic load for global societies. Despite the great social and economic importance, the complex symptomatology together with the lack of objective analysis methodology and the limitation of current biological models have made disorders difficult to classify and study. The recent development of brain organoids derived from human stem cells have enormous potential as a physiologically accurate downscaled in vitro model of the human brain. Even though this system offers promising approach for investigating the phenotypic foundation of these complex disorders, the lack of a reliable and non-disruptive system for investigating their properties limits their applicability in both basic research and pharmaceutical testing. The BRAINtSERS project aims to respond to this need combining advanced brain organoid models together with surface-enhanced Raman spectroscopy (SERS), providing a multidimensional dataset of a developing human neuronal tissue resolved both in time and space. In detail, the action will provide: (i) a label-free, highly sensitive technique for quantification and detection of biomolecules in brain organoids, (ii) a minimally-invasive system for cellular phenotyping, thus a non-destructive method for characterization of brain organoids during all developmental stages. Complementarily, the ER will deliver (iii) SERS-active bio-mimetic devices conceived for integration with organoid model and its genesis.


**Keywords:** Spectroscopy, SERS, Brain Organoids
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Physiological regulation of protein secretion in trichoderma' under Fifth Framework.

assistant: **Concept**

Secretion is one of the limiting steps of protein production in fungi. Isolation of new genes and proteins involved in secretion stress would improve production in fed-batch cultivations. Regulators and metabolic enzymes will be also analyzed, as well as the role of the redox environment.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Metasurfaces for ultrafast light structuring' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The METAFAST project aims to develop a novel class of synthetic nonlinear optical materials, or metamaterials, as a disruptive platform enabling unprecedented ultrafast dynamical control over polarization and wavefront of light. In particular, we will develop ultracompact all-optical modulators capable of faster than ever structuring of the spin and orbital angular momentum (SOAM) of light beams. Such ultrafast optical modulation offers an exceptionally robust method for the encoding of digital information in free space optical links, being also resistant to eavesdropping thanks to topological protection. The state-of-the-art of SOAM modulation technology to date is largely based on liquid crystals or digital micromirrors, which suffer from intrinsic limits in terms of speed (of the order of thousands bit per second) and prevent real-world telecom applications (demanding billions bit per second data rate). Thanks to our novel approach to ultrafast light structuring via nonlinear optical metasurfaces we will tackle the formidable challenge of increasing by 6 orders of magnitude the speed of SOAM modulators. Such a result could provide the metropolitan optical network with the kind of speed, robustness and security requested to support the 5G radio technology, thus underpinning the forthcoming fourth industrial revolution with fast communications for the so-called internet of things.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'A user-friendly approach to widespread gas monitoring', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Stick&Sense aims at making gas monitoring technology accessible to everyone. In a moment when society is more and more aware about the risks related to airborne pollution, the market is failing at providing a gas monitoring solution suitable for a massive, widespread use. Stick&Sense addresses, all-in-one, the main limitations of existing technologies: it is a disruptive one-stop solution capable of offering low cost, low complexity, high selectivity, good durability and broad detection range. Stick&Sense is a new colorimetric-electronic device consisting of a new low-cost optical reader and a new gas-specific colorimetric sticker designed to change its colour in presence of a target gas, that will operate together just attaching the sticker to the reader. With this genuine concept, Stick&Sense will offer an easy-to-use system for a wide range of gas sensing and monitoring applications, enabling a rapid expansion, not only among the traditional industry users, but also towards new, non-exploited mass consumers applications with millions of potential users. In short, Stick&Sense can revolutionize how people know the risks around them and relate with their environment to improve life-quality, safety and health. In this project, we will design and produce the first minimum viable demonstrator of the technology that will serve us to validate the Stick&Sense effectiveness both at a technical and at a commercial level. The team hosts all the expertise needed to implement this PoC from a technical and from a business points of view and counts with an extensive network of industry contacts to partner with in customer discovery, validation and eventual tech transfer agreements. The key innovations of the Stick&Sense solution have been recently discovered in ERC-funded activities
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'A Bidirectional MyoKinetic Implanted Interface for Natural Control of Artificial Limbs' (MYKI).

assistant: **Concept**

MYKI aims at developing and clinically evaluating a dexterous hand prosthesis with tactile sensing which is naturally controlled and perceived by the amputee. This will be possible by overcoming the conventional approaches based on recording electrical signals from the peripheral nervous system (nerves or skeletal muscles) through the development of a radically new Human-Machine Interface (HMI) based on magnetic field principles, both able to decode voluntary motor commands and to convey sensory feedback to the individual. Core of this system is a multitude of magnets implanted in independent muscles and external magnetic readers/drivers (MRDs) able to (i) continuously localize the movements of the magnets and, at specific times, (ii) induce subtle movements in specific magnets. In fact, as a magnet is implanted it will travel with the muscle it is located in, and its localization will provide a direct measure of the contraction/elongation of that muscle, which is voluntarily controlled by the central nervous system. In this way it will be possible to decode the efferent signals sent by the brain by observing a by-product of the muscle fibres recruitment. On the other hand, a movement induced in the implanted magnet by the external MRD, could provide a perceivable stimulus, conveyed to the brain by means of the peripheral sensory receptors present in the muscle (e.g. muscle spindles or Golgi tendon organ) or in the neighbouring skin (tactile mechanoreceptors). In this way we aim to provide tactile and/or proprioceptive sensory information to the brain, thus restoring the physiological sensorimotor control loop. Remarkably, with passive magnetic tags (that do not require to be powered-on) and wearable readers/drivers, it will be possible to implement a wireless, bidirect
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Towards 4D Imaging of Fundamental Processes on the Atomic and Sub-Atomic Scale' (2007-2013).

assistant: **Innovation**

State-of-the-art microscopy and diffraction imaging provides insight into the atomic and sub-atomic structure of matter. They permit determination of the positions of atoms in a crystal lattice or in a molecule as well as the distribution of electrons inside atoms. State-of-the-art time-resolved spectroscopy with femtosecond and attosecond resolution provides access to dynamic changes in the atomic and electronic structure of matter. Our proposal aims at combining these two frontier techniques of XXI century science to make a long-standing dream of scientist come true: the direct observation of atoms and electrons in their natural state: in motion. Shifts in the atoms positions by tens to hundreds of picometers can make chemical bonds break apart or newly form, changing the structure and/or chemical composition of matter. Electronic motion on similar scales may result in the emission of light, or the initiation of processes that lead to a change in physical or chemical properties, or biological function. These motions happen within femtoseconds and attoseconds, respectively. To make them observable, we need a 4-dimensional (4D) imaging technique capable of recording freeze-frame snapshots of microscopic systems with picometer spatial resolution and femtosecond to attosecond exposure time. The motion can then be visualized by slow-motion replay of the freeze-frame shots. The goal of this project is to develop a 4D imaging technique that will ultimately offer picometer resolution is space and attosecond resolution in time.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Molecular design of targeted recombinant antigenic proteins and evaluation of their immunological properties as subunit vaccines' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

This programme aims at the improvement of antigenic peptide-based vaccines by vehiculating these sequences through recombinant carrier proteins adequately tailored to this purpose. Vaccine formulations, although available for a variety of diseases caused by infectious pathogens, can still be improved in a number of ways, such as the elimination of potential risks related to the use of live or inactivated vaccines. The use of subunit vaccines consisting of antigenic proteins or peptides derived from the pathogens responds to criteria of safety and, due to the exploitation of recombinant DNA technology or chemical synthesis, of reproducibility and economy. Several peptide vaccines have been proposed, but their general applicability has been hampered, among the others, by stability and toxicity problems exhibited by the synthetic molecules. We propose here to use a combined approach derived both from the use as vaccines of peptide-based formulations and of recombinant proteins. We plan to construct, by insertion of appropriate oligonucleotides into suitable vectors, fusion proteins carrying peptides representing T- and B-cell epitopes in order to use them as possible vaccines. This technique should improve the stability and reduce the clearance of the antigenic peptides, possibly allowing to control its toxicity. This methodology also implies a greater reproducibility in comparison to the production of chemical adducts between synthetic peptides and carrier proteins. In recent years a growing interest in the study of peptide antigenicity in relation to the role of flanking sequences and protein topology in processing, presentation and recognition has been observed. The information available on the antigenicity of recombinant fusion proteins and their effect on the selectio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'On-demand production of entirely customised minimally invasive medical devices' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

With the development of powerful real-time imaging modalities, the sector of minimally invasive surgery has grown massively in the last decades. The easy and reliable navigation of the medical devices used in these environments is one of the key aspects for the success of such an operation. Currently, only a limited spectrum of devices for these interventions is available defined by the medical device manufacturers. The physician has to choose from this available (predefined) product range. However, for a successful outcome of advanced minimally invasive interventions it is essential to fulfil the needs of the physician who has to solve a complex task: navigating and operating in the human vascular system without having a direct view. Each physician has her or his own imagination of the ideal device for a specific intervention regarding handling and visibility. To maximise the ease of use of the medical devices and, thus, to optimise the outcome of the intervention a customised product would be the perfect solution.Therefore, the OPENMIND will develop the first highly flexible process chain for the on-demand production of entirely customised minimally invasive medical devices. This process chain will close the gap between efficiently produced standard products and individually designed products, enabling even the production of small batch sizes down to single batches in a continuous, automated and fully monitored process chain. The OPENMIND project will be using a guide wire as demonstrator device for showing the successful outcome of the project. The process chain will be completed by a comprehensive monitoring and data mining toolset. All relevant process data will be monitored and analysed in order to reduce development times by predicting appropriate parameter sets