RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Novel IΟnic LΙquid and supported ionic liquid solvents for reversible CAPture of CO2' (IOLICAP).

assistant: **Innovation**

The current requirements of the Post Combustion CO2 Capture (PCC) technology are: a) Reducing the parasitic energy load, b) Effectively addressing corrosion, c) Faster absorption/stripping rates, d) Less viscosity and less use of water, e) Confronting the problem of solvent degradation and volatility. These problems pose stimulating challenges for the synthesis of new solvents, aided by detailed molecular modeling of sorbate/sorbent interactions, and for new integrative module designs that enable their effective implementation in a process environment.In this context the IOLICAP proposal gathers expertise and skills form the domains of chemical synthesis of Ionic Liquids (ILs), molecular simulation/mechanical statistics, phase equilibrium, electrochemistry/corrosion, physicochemical/thermophysical characterisation, nanoporous materials & membrane technology and process engineering, aiming at the development and evaluation of novel Task Specific Ionic Liquid (TSILs) solvents that (a) short-term could replace the alkanolamines in currently existing PCC installations and (b) long-term would lead to the establishment  of a novel CO2 capture process, based on hybrid absorption bed/membrane technology that will incorporate TSIL modified porous materials and membranes.Task Specific Ionic Liquids exhibit enhanced CO2 capture capacity, which is above the 0.5 mol/mol limit of the currently applied amine solvents. Due to the high number of possible IL structures that will be synthesised during the project and the easy tuneability of their chemical and physical properties it is expected that loading capacities above the threshold of 1 mol/mol will be achieved. In addition, ILs are less corrosive than amines and are dissociated so there is no need for using large quantities of water
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Asymmetric Brønsted Acid Catalysed Enamine Aldol Reaction: New Methodology and Synthetic Applications' in the context of a Sixth Framework call.

assistant: **Objectives**

The catalytic asymmetric aldol reaction is the most important reaction for the construction of beta-hydroxy carbonyl compounds in enantioenriched fashion. These product compounds are key building blocks and intermediates in the synthesis of biologically im portant polyketide natural products such as the immunosuppressant discodermolide, and the family of potent anticancer compounds known as the spongistatins.To date, many of the asymmetric reactions that lead to the production of such beta-hydroxy carbonyl m otifs use stoichiometric amounts of chirality in the form of ligands or auxiliaries and/or toxic transition metal catalysts to promote the key carbon-carbon bond forming step. Here we propose a conceptually new approach to the beta-hydroxy carbonyl compoun d products by utilising simple" organic Bronsted acid catalysts (derived from commercial enantiopure diols and amines) to promote the aldol reaction between readily made enamine nucleophiles and readily available aldehydes. Preliminary studies have shown that these catalysts are indeed active and lead to moderate to good levels of enantiofacial control in the reactions. We wish to explore and develop this novel aldol reaction in the hope of securing the most scalable asymmetric route to beta hydroxy carbo nyl compounds to date. This will be possible by employing parallel synthesis methods to identify the optimal catalyst and reagent combinations. The proposed chemistry falls into the class of asymmetric organocatalysis - no toxic transition metals are used and the reactions should be efficient and clean. The reactions will be insensitive to moisture and air thus making them attractive to industry. The developed catalytic reaction will be investigated to probe the reaction scope and then applied to the synthe sis o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'New and Innovative Concepts for Helping European Transport Sustainability - Towards Implementation' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

NICHES+ aims to network actors engaged in developing innovative urban transport concepts. This proposal relates to the successful previous NICHES project, with similar objectives, but different topics. Both share the mission to stimulate a debate on innovative urban transport between stakeholders from different sectors, to promote the most promising new concepts from their current niche position to a mainstream urban transport application. NICHES+ will explore innovative urban transport concepts, which are high on the European & local agenda, while also looking into the needs of its potential users and implementers, i.e. concepts to increase accessibility to urban mobility options; concepts to increase the use & efficiency of infrastructure & interchanges; concepts to exploit functionalities of urban traffic management centres; concepts for automated & space efficient transport. These topics add to the work started under NICHES, which already examined a set of innovative concepts and successfully promoted them. NICHES+ will collect information & encourage networking by gathering urban transport experts in Working Group meetings. Selected concepts will be looked at in terms of their transferability to ensure wider replication. The project will develop policy notes for decision makers, implementation scenarios for selected cities and site visit programmes to promote the concepts. Recommendations for further research on urban transport innovation will be formulated. The project will work directly with cities, developing implementation scenarios for integrating innovative concepts in urban policies and move from the development of innovative mobility solutions to practical implementation. The added value of funding NICHES+, which can build on the basis of its predecessor pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'European cluster-led accelerator for digitisation of the circular economy across key emerging sectors'.

assistant: **Objectives**

Europe’s transition to a circular and climate-neutral economy is as much an environmental, economic and social necessity as it is an opportunity for European businesses and citizens. To meet the targets and ambition set out by EU Circular Economy policies and actualise circular value chains as a competitive advantage, DigiCirc will empower SMEs to leverage digital technology as a key enabler for innovative circular products/ services, processes and business models.To this end, DigiCirc will create and coordinate the DigiCirc innovation network, facilitated by an engagement campaign of 3 partner clusters, to bring together a wide-spectrum of ‘triple-helix’ stakeholders (local/ regional authorities, big industry actors, SMEs, RTOs, civil society, etc.). 3 strategic high-growth domains will be in scope (Circular Cities, Bioeconomy, Blue Economy), each represented by a leading cluster in the field. The Ecosystem will lay the foundation for a holistic, dynamic and cross-border/sector open space for innovation, implement through the DigiCirc accelerators (3 calls, one in each target domain).The accelerators will be run by innovation support experts to transform validated concepts into robust business models towards a commercial launch. This will involve (i) tailored business support: courses and coaching; (ii) identifying and establishing strategic partnerships (facilitated by a dedicated Matchmaking Tool) to create complementary consortia (thematic & SMEs with a LSD enabler partner, e.g. industry, local government); (iii) two circular data platforms to simplify data use and integration across complex value chains and environments thus boosting circular business plans and concepts.Finally, A DigiCirc Roadmap will be drafted to define the path for digital-enabled circular inno
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Multi-modal Diffusion Tensor Imaging of Active Neurons: Searching for Functional and Other Biophysical Components'.

assistant: **Concept**

Diffusion Tensor Imaging (DTI) is a central tool in brain research and in the clinical neurological diagnosis. Despite its popularity in research and in clinical applications, the biophysical mechanisms underlying DTI are not fully understood. For example, with respect to essential parameters such as the amplitude of change of the apparent displacement post insults, the orientation of maximal change and its timing, theoretical models of displacement fail to describe the kinetics of water displacement following insults. Moreover, it was suggested that neuronal activity can directly modify the diffusion weighted MR signal to provide functional images with high temporal and spatial resolution. Our working hypothesis is that water displacement that occurs due to active cellular mechanisms, contributes significantly to the signal measured in DTI. We are interested in quantifying the contribution of various cellular events to the signal measured in DTI, where a pivotal mechanism that will explored is the suggested water displacement that is linked with neuronal activation. To address the limits of detectability of neuronal excitation via MR, we suggest employing a three-source, multi-modal system: MRI, electrical potential mapping and fluorescence microscopy of neuronal organotypic cell cultures. The use of organotypic cultures bypasses major sources of physiological artifacts such as blood flow and pulsation. MRI is performed with a low-field open MRI system. Electrical recordings will be performed simultaneously with a multi-electrode array system that will provide 2-D ‘imaging’ of neuronal electrical activity and optical microscopy will allow imaging of Calcium release. This multi-modal imaging system will allow testing previously proposed mechanisms of neural detection by
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'The role of cell signalling and infochemicals in marine Algal-Virus interactions', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Emiliania huxleyi is a cosmopolitan phytoplankton belonging to the coccolithophores, eukaryotic phototrophs that dominate the modern oceans. Coccolithophores are considered to be among the largest producers of calcite on earth, and as such, are a major vehicle for the transport of carbon to the deep sediments. They are important producer of DMS, a gas thought to strongly influence climate regulation. E.huxleyi forms massive annual blooms in the oceans that are routinely infected and terminated by giant double-stranded DNA lytic viruses (Phycodnaviridae). Currently, very little information is available on the molecular basis for the intricate interactions between E.huxleyi and its specific viruses. We are still lacking a fundamental understanding of the life cycles of Phycodnaviridae within their hosts and of the genes involved in lytic versus chronic infections. In this project we will investigate the co-regulation of intracellular signal transduction pathways involved in host/virus during infection. We will specifically examine the role of chemical signals (infochemicals) and their potential role in mediating the interface between host and virus. The recent availability of genomic resources for the E. huxleyi host and its specific virus 86 (EhV86) provide an unprecedented opportunity to explore cellular pathways triggered during execution of viral infection and to gain insights into the origin of programmed cell death (PCD) in unicellular organisms. We will analyze natural coccolithophore blooms with our newly-discovered biomarkers as “fingerprints” to evaluate the importance of viral infection during bloom succession. This work has great potential to reveal novel insights into the molecular mechanisms of virus-host interactions, including the role of virally-induced i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'A framework for fleet and area based fisheries management' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

The chief objective of AFRAME is to develop a framework for fleet and area-based fisheries management. The project has three research themes: 1, the development and testing of a framework for describing fleet activity in terms of the fisheries in which the fleet participates, and how it allocates its effort across these fisheries; 2, the development of indicator approaches to summarising information and presenting advice in relation to multi-fleet, multi-species fisheries; and 3, stakeholder perceptions and institutional implications of a shift to fleet and area based management. These themes will be developed through application in three contrasting case study areas: 1, the demersal fisheries of the North Sea, which represent a relatively data-rich area with relatively few important commercial species, all of which are assessed routinely; 2, the demersal fisheries of ICES areas VII and VIII (the Channel, Celtic Sea and the Bay of Biscay), which has a relatively high number of target species, not all of which are assessed; and 3, the Mediterranean, which has a high number of target species, with very little stock assessment information.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Ultrasound-based techniques for soft jammed materials' (USOFT) targeting Seventh Framework.

assistant: **Abstract**

Soft materials are involved in most parts of our everyday life. In spite of a tremendous industrial importance, their properties still confront the physicists with challenging questions. Indeed, the constituents of soft materials are often stuck into a disordered structure, as for oil droplets in a concentrated emulsion like mayonnaise and for attractive particles in a colloidal gel. This phenomenon is known as ""jamming"" and leads to solid-like properties at rest that slowly evolve in time as the system ""ages"" under spontaneous rearrangements. When a jammed material is submitted to some external stress, a ""yielding"" transition from solid to liquid behaviour is commonly observed. Besides the fundamental issues raised by such out-of-equilibrium, glassy features, the design of soft materials that can strongly respond to a well-controlled excitation is of great interest for practical applications.This project aims at developing original tools for both physical investigation and design of soft jammed materials, based on the use of ultrasound. We will first set up ultrafast ultrasonic imaging techniques in the single and multiple scattering regimes in an attempt to overcome some limitations of current optical methods and to elucidate jamming, aging and yielding processes in a wide variety of model and real materials. High-intensity ultrasound will then be used to mechanically stress jammed materials and trigger local rearrangements or even large-scale structuration, leading to new insights into the physics of jamming and to innovations in the field of material design.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'New Inhibitors of Bacterial and Fungal Cell Wall Biosynthesis' (2002-2006).

assistant: **Concept**

Oligomeric materials consisting of repeat units of carbohydrate monomers frequently represent crucial cell components that are essential for the viability of a whole host of different organisms. For example the mycobacterial cell wall contains several uniq ue carbohydrate structures, such as the arabinogalactan and arabinomannan portions, that do not appear in mammalian biology. It has previously been demonstrated that the correct biosynthesis of these structures is essential for bacterial survival. Therefore inhibition of the biosynthesis of these types of oligosaccharides represents a new and attractive therapeutic strategy against mycobacteria and in particular against tuberculosis. Similarly chitin, which is a (1-4) linked polymer of N-acetylglucosamine, is a major constituent of both fungal cell walls and insect exoskeletons. However chitin also does not appear in mammalian systems, and therefore inhibition of chitin biosynthesis represents a selective strategy for the development of novel fungicides and insecticidal agents.This research program aims to develop a new strategy for the inhibition of such bacterial and fungal poly- and oligosaccharide biosynthesis by a completely novel mode of action. This research proposal concerns investigations into the feasibility of using this strategy as a method for inhibition of mycobacterial cell wall biosynthesis, and also for the inhibition of fungal cell wall biosynthesis. These studies are designed to investigate the general feasibility of this approach, and hopefully to provide a demonstration of and proof of concept" for a new approach to the inhibition of oligosaccharide biosynthesis, which may in the near future represent a novel and general therapeutic opportunity against infective organisms, particularly those which
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Disruptive Nano Photonics-based bio sensing platform for simultaneous analysis of multiple allergens in food industry' (SaPher).

assistant: **Innovation**

Food allergies affect over 17M people in Europe and increasing at a 2 digit prevalence rate. With no cure, the only successful method to prevent allergic reactions is to strictly avoid all foods containing the allergen. Hence, to identify these, the consumers rely on an accurate product labelling.The labelling of allergen contents for the industry is however not trivial, it does not only depend on the composition of the product, but also on the possible cross-contamination with allergens from other products.The current lack of standardized food allergen control plans and cost-effective allergen testing tools, drives food manufacturers to adopt over cautious labelling strategies. As a result, 90% of products with ¨may contain¨ allergen labels do not contain any. This reduces the choice of safe food for the allergic population (39.1M people), leading to a risk taking behaviour.SaPher project will disrupt the food allergen assessment market thanks to the development of an allergen assessment procedure supported by the industrialization and commercial deployment of our full automatic SaPher nano-photonics biosensing allergen test platform. SaPher will simultaneously assess up to 6 different allergens in food matrices, reducing turnaround times and cost by over 70% in comparison with current golden standards.To reach market, we will elaborate a standardized risk assessment method (DTU), develop the antibodies of interest not comercially available in the market for the target industries (INGE), industrialize and optimise our technology for mass production (LUME and UPV) and demonstrate both technology and procedure with the meat, dairy and bakery industries (NESTLE) as well as independent laboratories under operational conditions.As a result, we expect SaPher to be adopted by