RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'The Spanish Telecommunication Sector and the Development of AI Products from a Gender Perspective' in the context of a Horizon 2020 call.

assistant: **Objectives**

The rise of algorithm-powered technology in the telecommunications industry has been criticised for reproducing gender bias, particularly in Artificial Intelligence-driven (AI) products. This interdisciplinary and intersectoral project explores the gender bias within the Spanish telecommunications industry as a direct consequence of the lack of women in the sector. The purpose is to develop a multi-methodological study that allows to draw attention and evidence the gender gap and the consequent lack of a gender perspective within this industry in Spain. The central hypothesis is that the current gender gap in the sector leads to lack of integration of a gender perspective leading consequently, to the reproduction of gender bias in AI technologies. This, as a result, produces a setback in gender equality. To explore this, the study asks the following questions: what is the degree of the gender gap within the telecommunications industry in Spain? Are measures being taken to address this? To answer these questions, I will gather data on two levels: first, at the general level by implementing a quantitative survey-based methodology, targeting 400 industry insiders to gain information on the gender gap in the overall sector; and second, at the specific level, by carrying out a case-study through my secondment at Telefónica, Investigación y Desarrollo (TID), a Spanish leading research centre in new technologies where I will use qualitative-based methodologies to investigate its gender bias and its lack of integration of a gender perspective. A major outcome of this research is the production of a report to be handed to TID with specific guidelines for the incorporation of a gender perspective that will help them reduce their gender bias in their AI technologies and improve th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Microbial marine communities diversity : from culture to function'.

assistant: **Concept**

This proposal investigates marine microbial biodiversity by obtaining cultures of novel microbial groups of marine origin, measure their functional origin and using molecular identity indicators. We plan a systematic approach that includes scale screening of culture conditions using microtiter plates equivalent to 100000 classical experiments of liquid media enrichments, coupled to extinction dilution to guarantee that at least all the main physio-ecotypes have a chance to grow. The vast database of the organisms that develop under combinations of nutrient regimes will be of critical value in making rapid progress to describe marine microbial biodiversity. Many non-conventional techniques to obtain pure cultures in a single step will be applied by the use of genetic manipulation or flow cytometry. A collection of several thousand strains will be obtained which will be analysed for their role in the ecosystem functioning.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'A new Agricultural Industry Standard for Autonomous Plant Production' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

RoBoTec PTC GmbH is a young company and already highly awarded SME specialized in the automation of breeding and mass propagation of plants via plant tissue culture. Based in northern Germany RoBoTec PTC GmbH was founded as a spin off of Bock Bio Science GmbH, a professional tissue culture laboratory and nursery, service laboratory for cloning and propagation. In the 100 years long company history several market-disrupting technologies have been developed by Bock. Now the RoBoTec PTC GmbH makes a further step to become a technology leader and system supplier for autonomous in vitro plant cultivation by developing and marketing the RoBo®Cut. As a unique solution for in vitro plant propagation of high-quality plant species the innovative system uses 3D image recognition and deep learning software, able to recognise complex plant structures, cut them without contact and place them in new culture vessels - all automatically in a completely sterile production cell. Potential customers rethink laboratories as the RoBo®Cut helps to achieve new levels of quality and efficiency. Better work planning and increased productivity will be possible, but the decisive aspect here is, that the system offers the opportunity to brings plant propagation back to Europe, which has been handed over to low-wage countries due to cost pressure. Environmental costs, process risks and a considerable transfer of knowledge can now be avoided. As a first mover we subsequently want to equip all plant laboratories with the RoBo®Cut. system as a standard equipment for PTC plant propagation. For an initial market introduction, Bock addresses the European and American markets. The global distribution network will help to quickly enter the world market and generate 15% relevant market share and a turnover o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'European Stroke Research Network'.

assistant: **Innovation**

The European Stroke Research Network (EUSTROKE) will be a collaborative effort that brings together researchers, government, industry, the non-profit sector and patient group associations. This network will put Europe at the forefront of stroke research through its multi-disciplinary research program, high-quality training for European scientists and clinicians, and national and global partnerships. A primary focus of the EUSTROKE research programme is to improve our understanding of the neurovascular unit to enable better prevention and treatment of stroke. This involves elucidation of dynamic interactions of vascular, cellular and matrix signalling in both the grey and white matter of the brain. Our research strategy looks beyond the single cell for a more integrative answer to ischemic brain damage. The goals of EUSTROKE will be addressed by a wide variety of multidisciplinary European research teams working on various aspects of the neurovascular unit. Thus EUSTROKE will promote integration of both clinical and experimental research teams in cerebrovascular biology, imaging, prevention, and reperfusion with a common focus upon the NVU.  The project will aim at developing new approaches for targeting the NVU to improve potential combination or multi-targeted treatments for stroke. Combination therapies that target the entire neurovascular unit, promote cell survival mechanisms and extend the therapeutic time-window for reperfusion therapy will provide new opportunities to meet the challenges of stroke. Moreover, developing therapies that maintain proper NVU function or prevent age-associated alterations in the NVU may find use in the prevention or treatment of cerebrovascular disease. Thus, the collaborative project will integrate its vast multidisciplinary capacitie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Federated IT for a sustainable environmental impact' (FIT4Green) targeting Seventh Framework.

assistant: **Abstract**

FIT4green aims at contributing to ICT energy reducing efforts by creating a energy-aware layer of plug-ins for data centre automation frameworks. The plug-ins enhance existing IT solutions deployment strategies by moving computation and services around a federation of  IT data centres sites, with the final goal to minimize the overall power consumption figure. Without giving up on compliance to Service Level Agreements (SLA) and Quality of Service (QoS) metrics, FIT4green optimization layer will be placed on top of the current data centres management tools to orchestrate the allocation of ICT resources and turning off unused equipments.The project will consider the deployment options of whole IT solutions, from the client devices to the data centres where the applications and services are dynamically allocated, including the impacts of the different networks providing the needed connectivity.The project rationale builds on shortcomings of current systems:-\tVirtualization, consolidation and data centre automation techniques provide a mean to achieve flexibility of IT solutions, but reduced energy consumption (achieved as side effect of server number reduction) is generally not considered among the Key Performance Indicators (KPIs) of any deployment options;-\tService Level Agreements don't include any metrics related to environmental footprint.FIT4green will explore both optimal deployment solutions satisfying existing SLAs with minimal energy consumption and next-generation energy-aware SLA statements - with minimal tradeoffs with respect to current metrics - providing high global improvements on environmental sustainability KPIs.FIT4green approach is potentially applicable to any data centre type; the project will run pilots using three representative data centres typ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Decoding the contribution of TDP-43 for synaptic failure in Alzheimer's Disease' to be submitted under Horizon Europe.

assistant: **Abstract**

Alzheimer’s Disease (AD) is an adult-onset disorder characterized by progressive neuronal loss and synaptic dysfunction, leading to severe cognitive decline. Nuclear loss and pathological inclusions of TDP-43 protein have been identified in 20-50% of AD patients, which associate with higher odds of cognitive decline, and faster brain atrophy rates. TDP-43 regulates RNA metabolism, and many of its RNA targets converge at synaptic function. Studies from me and others identified TDP-43 dependent mis-splicing in AD patients with TDP-43 pathology, strongly suggesting that TDP-43 loss-of-function is an important, yet understudied, pathway in AD. Here, I hypothesize that TDP-43 loss-of-function in AD leads to defects in its synaptic RNA targets, which in turn contribute to synaptic dysfunction and thus cognitive defects. I will use post-mortem tissue, induced pluripotent stem cells (iPSCs) and mouse models to characterize the impact of TDP-43 loss in synaptic function and composition, and matched these with RNA alterations resulting from TDP-43 loss-of-function. This will uncover novel synaptic signatures of TDP-43 dysfunction in AD, and offer new insights into neurodegeneration in AD. I will leverage my PhD training in synapse physiology and postdoctoral expertise in TDP-43 proteinopathy while working under the guidance of Dr. Ana Luísa Carvalho, a leading expert in synapse biology of disease. Dr. Carvalho is a dedicated mentor, and her lab at the Center for Neuroscience and Cell Biology (CNC) in Portugal is part of a top-tier research center with state-of-the-art facilities and a vibrant academic environment. This experience will be crucial for developing the scientific and transferable skills needed to achieve my goal of becoming an independent researcher within 2-3 years.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Union of Light-Ion Centres in Europe' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

ULICE is a 4-year project set up by 20 leading European research organisations, including 2 leading European industrial partners (Siemens and IBA), to respond to the need for greater access to hadron therapy facilities for particle therapy research. Project coordinator is the Italian Research Infrastructure Facility CNAO (Milan). Both existing European Hadron Research Facilities in Heidelberg and Milan are partner and together with the next operational centre (Philipps-Universität Marburg; yr4) they will provide 624 hours of beam-time (141 users, 52 projects) to external researchers. Future facilities like MedAustron, Etoile and Archade also participate in ULICE, which will result in a strong integrated network. Full exploitation of all different resources, unrestricted spread of information and the improvement of existing and upcoming facilities are provided by using grid-based data sharing. The project is built around 3 pillars with measurable outputs. These outputs will be exploited by the (future) facilities and (partly by) the industrial partners: 1. JRA - focus on development of instruments and protocols: new gantry design, improvement of four-dimensional particle beam delivery, adaptive treatment planning, mechanisms for patient selection to the whole European Community and database development for specific tumours which can best be treated using carbon ion. 2. Networking - increasing cooperation between facilities and research communities wanting to work with the research infrastructure. Outputs will be (among others): a report on recommendations for strategically optimal locations for future RIs throughout Europe, training to new users 3. Transnational access: 2-step approach, using a combination of pre-defined (within ULICE) clinical trial programmes to allow
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Si based Layer Stacks for Rear-Side Passivation and Enhanced Reflection of GaInP/GaInAs/Ge Triple-Junction Space Solar Cells' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Solar cells are the preferred method for powering today’s satellites. The cell efficiency determines the available power and is hence of exceptional importance for any spacecraft equipment or system. Besides the efficiency that is directly linked to the solar array power (W/m2), solar cells define also further Key Performance Indicators such as specific mass (kg/m2) and manufacturing costs (EUR/W). The SiLaSpaCe proposal will address these needs by developing next generation, high performance, GaInP/GaInAs/Ge multi-junction space solar cells with reduced weight, high radiation stability and increased efficiency. This ambitious goal will be achieved by the introduction (spinning-in) of Si photovoltaic technologies which are absolutely new for space applications and which will lead to a disruptive development. These measures will furthermore allow the introduction of thinner Ge wafers and metamorphic top structures leading to increased efficiency and to reduced weight bringing GaInP/GaInAs/Ge multi-junction space solar cells significantly beyond the state-of the art which are lattice-matched GaInP/GaInAs/Ge triple-junction solar cells with a Beginning-of-Life (BOL) efficiency of 30%. In the SiLaSpaCe project GaInP/GaInAs/Ge multi-junction space solar cells shall reach a BOL efficiency of 33%. The proposal relates clearly to the EU call topic ""H2020-LEIT-Space-Competitiveness of the European Space Sector-2015”. Its main objective is to preserve European independence and competitiveness in the space market by incorporating and developing a brand-new space solar cell technology. The proposal’s ambitious developments will enhance new and key enabling technologies (KET) like energy production, materials and structures as well as additive layer manufacturing techniques. Finall
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Development of a new methodology for the synthesis of mercapto amino acids for protein synthesis by cysteine-free native chemical ligation'.

assistant: **Concept**

Proteins are in the heart of almost every single biological function and therefore are essential tools for drug discovery. Although the use of recombinant DNA techniques has been successfully applied to the synthesis of many proteins, the access to proteins bearing non natural amino acids, naturally obtained through post-translational modifications, remains limited. However, with the invention of Solid Phase Peptide Synthesis (SPPS) by Merrifield, the total chemical synthesis of peptide containing non-proteinogenic amino acids can be easily achieved. Nonetheless, the SPPS technique is only suitable for peptide chains of a length below 50 amino acids. The problem related to the synthesis of large peptide or even proteins was overcome by Kent et al. who were able to link peptide fragments together by Native Chemical Ligation (NCL). NCL involves the reaction between the N terminus cysteine of a first fragment and the thioester C-terminus of a second fragment. After the transthioesterification, a S -> N acyl transfer yields the desired native amide bond.  Despite this ground-breaking discovery, NCL remains limited to cysteine-containing proteins. In 2001, Dawson et al. introduced the ligation-desulfurisation technique. This latest advance paved the way to cysteine free NCL and prompted many research groups to focus their efforts on the preparation of beta- and gamma-mercapto amino acids for use in ligation-desulfurisation strategy. Unfortunately, the 7 to 16 steps required for their synthesis considerably restrain their uses by peptide chemists. The proposed project is directed towards the elaboration of a straightforward synthetic route to access beta-thiol amino acids from a single precursor using the latest breakthroughs in C-H activation technique. In order to demonstra
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Modelling of fine fibres forming in hot turbulent multiphase flow' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

Saint-Gobain, a leading materials company (glass, ceramics, plastics) and first in the world in insulation, is offering two successive fellowships positions jointly with the European Commission (Marie Curie Industry Host Fellowships scheme) to model the forming of fine fibers (micron scale) in hot turbulent multiphase flow. Studied phenomena are the stretching of glass fibers and their interaction with binder droplets.1. Modeling the interaction of a single fiber with a hot turbulent jet (1st fellowship, 2 years) Two approaches will be considered in this part:First approach : modeling by using drag coefficient and heat transfer coefficient : determination of these coefficients in function of the average velocity and turbulence intensity through mathematical modeling and numerical simulation ; validation through comparison with experimental data obtained on the trajectory and diameter of fibers using a specific device developed by Saint-Gobain.Second approach : modeling of the interaction between a very fine fiber (diameter < 10 microns) and the eddies of the gas jet by mathematical modeling and numerical simulation.2. Modeling of several fibers, interaction between fibers and binder droplets (2nd fellowship, 2 years). Interaction between fibers; between fibers and binder droplet; determination of the droplet break-up model when a binder droplet impact a fiber; numerical simulation using Lagrangian or Eulerian approach.1^st profile : post-doctorate researcher having pursued doctoral studies in the theoretical modeling of turbulence. Experience in multiphase flow and heat transfers would be appretiated.2^nd profile : post -doctorate researcher having pursued doctoral studies in the modeling of multiphase flow Experience in numerical simulation of diphasic turbulence would