RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Gold Nanoprisms as Raman Signal Amplifiers for Bioimaging of Lung Cancer' (Raman), addressing dissemination and exploitation.

assistant: **Impact**

Raman spectroscopy is a powerful tool for probing biochemical changes in situ at tissue level. The vibrational profile can provide invaluable molecular details for medical diagnosis and disease prognosis. Important technological as well as health and safety considerations, however, limits its clinical application, as spontaneous Raman is a relatively weak effect and high laser powers are required for rapid screening. Surface-enhanced Raman scattering (SERS) makes is possible to probe single molecules adsorbed onto a silver or gold nanoparticle, greatly enhancing the sensitivity of spontaneous Raman and therefore potentially significantly reducing screening times. However, the SERS sensitivity from spherical gold nanoparticles is still insufficient to detect trace biomolecules and/or the interaction between biomolecules, which may be overcome through using novel shape nanomaterials as SERS substrates for the improvement of the bio-detection limit. Recently, Pegylated gold nanoprisms (AuNPrs) have been successfully employed as signal amplifiers in multimodal in vivo imaging of cancer cells, and therefore pose a great potential for Raman spectroscopy as well. Excellent biocompatibility properties are known for Pegylated AuNPrs, with side lengths of 120nm and thicknesses of 10nm. They absorb strongly at a wavelength of 830 nm, with co-efficients of up to 37 µg.mL-1•OD-1, a wavelength within the tissue transparency window, promising deep penetration in vivo This project will explore the optimisation of Pegylated AuNPrs for surface enhancement of the Raman signal (SERS)of their local cellular environment for probing disease in vitro and ulimately in vivo. Lung cancer is the most common cause of death from cancer in the EU and is therefore chosen as a model for the development
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Diversibus Viis Plurima Solvo' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Foundation models represent a paradigm shift in AI, exhibiting remarkable capabilities across multiple tasks. Their true potential lies in generalizing across diverse domains and modalities, a largely untapped frontier. DVPS advances this frontier by focusing on multimodal foundation models (MMFM), aiming to harness their capabilities across various application domains.DVPS emphasizes three core benefits of MMFM: label efficiency, compute reusability, and engineering efficiency. However, achieving these benefits in multimodal settings presents challenges such as modality-specific architecture and cross-modal alignment. To overcome these, DVPS aims to develop generalizable methods that work across diverse modalities and domains, creating a unified framework for MMFM development and integrating new modalities into existing models.The project focuses on generating foundational knowledge, delivering tested methods, and creating algorithms to expand MMFM capabilities across domains like cardiology, geo-intelligence, and language communication. DVPS also includes two ""surprise domains"" to drive innovation by challenging initial assumptions.Key objectives include the development of AutoDVPS, a toolkit for automated MMFM design, and the creation of DVPSBench, a benchmarking suite for evaluating MMFM across tasks and domains. DVPS aims to foster a European ecosystem for MMFM research, promoting transparency, fairness, and ethical compliance in line with European values. Through collaboration and open-source contributions, DVPS seeks to standardize and advance MMFM as a scientifically rigorous discipline.""


**Keywords:** Machine Learning, Multimodal Data, Transfer Learning, Evaluation Metrics, Open Source Software, Healthcare, Cardiology, Earth Observation, Language Processin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Electrochemical capacitors based on controlled porosity carbons and ionic liquids: role of pores, their sizes and accessibility for electrolyte ions' (2002-2006).

assistant: **Concept**

Nowadays needs for energy storage resulted in extensive research on electrochemical capacitors (ECs), based on activated carbon electrodes. The advantage of such devices is in the possibility of high-density energy storage as a result of developed surface area and pore volume of carbon materials. In the EC systems, aqueous, non-aqueous and solid polymer electrolytes have been used. In this proposal, we suggest using a new type of electrolyte, ionic liquids, which are organic salts consisting entirely of ion s and remaining in the liquid state at ambient conditions. Moreover, practically lack of vapour pressure makes them environmentally friendly liquids.A few recent studies of applications of ionic liquids as electrolytes for ECs point as a significant advantage the high capacity, comparable to that for solutions of organic salts and also the possibility to store high energy due to a broader practical electrochemical stability window. The application of ionic liquids as electrolytes can also bring another advantage, which is in lack of the solvent whose presence and interactions with ions (solvation) and with carbon surface must affect the performance of those devices. To investigate these effects, activated carbons with well-defined pore sizes are needed, which is not the case for traditional activated carbons of broad pore size distribution. Here, the window of opportunity opens in the template carbonisation method.Using well defined inorganic materials as templates, the replicas or carbon copies of the porous structure can be obtained after introducing an organic precursor, its carbonisation and dissolving an inorganic matrix. A significant advantage of that method is in the possibility of tailoring the pore sizes using various templates as well as various organic pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Finding the True Path Beyond the Standard Model' in the context of a Seventh Framework call.

assistant: **Objectives**

The Standard Model of Elementary Particle Physics is the best description of Nature we have. Yet we know that it must be incomplete, and we need to find the correct extension, which is done by developing new mathematical models and investigating their consequences.Contrary to the usual approach of constructing ""yet another model"" that can only explain particular aspects, we propose to identify the decisive characteristics of entire classes of theories, and use this knowledge to systematically develop new models. These classes will be tested thoroughly concerning their internal consistency, their experimental predictions, and their implications for the cosmology, instead of checking only the few points these models have been specifically designed for.Many theories are based on similar grounds, which is why there exist ways to classify them, test their predictions in a unified way, and detect remaining possibilities for new models. These principles shall be successfully searched for, which will be achieved by the unique combination the proposed fellow’s skills and the world-leading expertise of the two scientists in charge. This knowledge is ideally complemented by the fellow’s talent in combining a profound knowledge of theory with new results from on-going experiments, maximizing synergetic effects.This is the ultimate up to date strategy to optimize the use of the outstanding experimental activities currently going on in and funded by Europe, from the Large Hadron Collider at CERN to groundbreaking Dark Matter and neutrino experiments in Italy, France, or Germany, which will all yield results in the very near future.In short, one has to successfully connect expertise from different sectors in particle theory, identify generic principles, and link them correctly to ex
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Non-contact ultrasonics: new methods for large and small scale measurements'.

assistant: **Objectives**

Ultrasonic measurements have a wide range of applications, from non-destructive testing (NDT) on bridges, pipeline and railway track, to measurements of elastic constants of single crystals, whose properties are key to the development of new magnetoelastic devices. Traditional techniques require the transducers to be in physical contact with the sample, and non-contact ultrasonics (NCU) is attracting more interest. Improvements to NDT through the use of NCU are leading to new applications in hostile environments, such as measurements at high temperatures or of moving samples, helped by the lack of need for couplant. This proposal covers applications of great importance which could benefit from the use of NCU. The problem of partially closed cracking in metals will first be investigated. Stress corrosion cracking can cause catastrophic damage to pipeline, and there is no current technique which can reliably detect and characterise it. The physical phenomena associated with transmission of the ultrasound will be probed to develop new methods of detecting defects using laser ultrasonics and electromagnetic acoustic transducers. The project will investigate and explain the behaviour of the ultrasonic interactions with defects in the vicinity of cracks, including non-linear behaviour around a partially closed crack. Later work will use ultrasound for elastic and magneto-elastic measurements of single crystals. These measurements are able to quickly and inexpensively identify interesting and important new systems, saving the time and resources which may have been used to investigate samples using neutron studies. New NCU techniques will be developed, capable of detecting magnetic phase changes through variations in the coupling efficiency. The benefits of combining the result
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'BEAT B-cell Lymphoma: Biomarkers of Effective CART19 Assessed in the Tissue Microenvironment' (2021-2027).

assistant: **Concept**

Project Title: BEAT B-cell Lymphoma: Biomarkers of Effective CART19 Assessed in Tissue microenvironmentB-cell lymphomas, encompassing Follicular Lymphoma (FL) and Large B-cell Lymphoma (LBCL), pose significant health concerns. While the use of T-cells modified with a chimeric antigen receptor targeting CD19 (CART19) offers a potential breakthrough in treating these malignancies, it is imperative to unravel the intricate dynamics between the CART19 and the tumor B-cells within their unique tissue microenvironment (TME).The ""BEAT B-cell Lymphoma"" initiative is poised to transform lymphoma therapeutic strategies. More than just advancing the status quo, this project is geared towards unveiling novel biomarkers that facilitate immediate feedback on therapeutic outcomes. These newfound markers will empower clinicians and patients with predictive tools for CART19 interventions and serve as cornerstones for redefining inclusion criteria in subsequent clinical trials. But the ambition of this endeavor goes beyond mere biomarker discovery. It promises in-depth revelations on how CART19 impacts actual patient-derived tissues, deepening our knowledge and inspiring fresh treatment avenues. The short term concrete vision? Fine-tuning CART19's performance and honing the initial patient selection process.As a medical doctor with a specialization in hematopathology, I've offered numerous diagnoses of B-cell lymphomas, grounded in histological and molecular markers predominantly sourced from tumor B-cells. My foundational training as an immunologist has sharpened my curiosity, drawing my attention to the often underemphasized tissue microenvironment. My affinity for bioinformatics further equips me to navigate and interpret vast datasets efficiently. To ensure the success of this proj
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Stable miniaturised self-aligned fibre optic fabry-perot cavities for sensor applications' (1994-1998).

assistant: **Concept**

Research objectives and content The aim of this project is to improve the miniaturisability, manufacturability, and stability of fibre-optic based interferometric temperature and vibration sensors by the procedure of fusing a glass fibre to a substrate rod. This will be performed with minor modifications to a fused biconical tapered coupler fabrication facility. The cavity will then be formed by micro-sawing out a notch from the fibre, or by simply cleaving the fibre, leaving the substrate intact to support the cavity in its self-aligned state. The dimensions of the notch may be varied to suit the application The device will operate as a sensor by mechanically vibrating, or thermally expanding or deforming. Mechanical vibration leads to opening and closing of the gap by small amounts. Because the device will work interferometrically, very small movements may be detected even with low-reflectivity surfaces. The small movements in fibre face angle are not envisaged to affect significantly cavity losses. Deformation due to thermal expansion will similarly cause the cavity width to change. Other procedures such as metallisation to form mirror surfaces will also be explored. Training content (objective, benefit and expected impact) The technical impact is expected to be a new type of sensor element of interest to European industry and research communities. The project will help me further my work on the development of optical fibre devices and sensors, as well as introduce me to new applications from mechanical engineering, such as vibration and thermo-dynamics. I will also bring to the host institution many ideas learnt during the current post-doctoral fellowship, in the areas of optics, interferometry, and optical fibre sensors and applications Links with industry / indust
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Processing Activates Specific Constraints for Language Acquisition' (PASCAL) targeting Seventh Framework.

assistant: **Abstract**

PASCAL is a project to investigate the human ability to acquire language, and the underlying biological endowment that provides specific language learning mechanisms. Clearly, language acquisition (LA) starts at birth, rendering neonates the first population to investigate, to get the full picture of how LA unfolds. PASCAL’s first objective is thus to investigate core cognitive dispositions, which render neonates able to interact with speech signals. We will focus on the neonates’ and young infants’ abilities to process auditory signals and to store them in memory. The second objective is to identify biological constraints that determine LA dispositions, in particular we will study the speech perception preferences in infants who do not yet produce speech, to understand if practice with the articulators is necessary to determine such preferences. The third objective, linked to the former one, is to understand the beginning of prosodic grouping abilities that might trigger the initialization of grammar. The fourth objective is to identify the origin of the functional specialization of segmental categories in speech processing. How early in life do consonants become specialized for lexical processing, and vowels for the extraction of regularities? The fifth objective is to explore a basic issue in LA, namely the type of bilingual exposure at different ages and their consequences for the enhancement of executive functions. We will also develop games to promote executive functions to complement the full immersion into a new language that children may get at different points in time. The results of this part of our project might have an important impact on educational policies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Signalling network regulating tooth development' (TOOTH) under Seventh Framework.

assistant: **Objectives**

In teeth sequential and reciprocal interactions between epithelium and ectomesenchyme play a pivotal role in their development. A progress has been made in identifying various key transcription factors and signalling molecules participating in epithelial–mesenchymal signalling, involving different pleiotropic morphogens, such as bone morphogenetic proteins, fibroblast growth factors, hedgehog and Wnt proteins as well, which are responsible for patterning, morphogenesis and differentiation. There is a growing interest in different stem cell niches located in tooth germs and how they provide cues for the maintenance, proliferation and differentiation of dental cells. The rodent incisor has a unique property: it exhibits asymmetric growth and enamel distribution due to the presence of discrete stem cell compartments at the apical part. The main research goal is to identify different key signalling molecules that regulate stem cell proliferation in the rodent incisor epithelial stem cell niche. As a former MC EIF fellow, I learned the details of in situ hybridization, tissue culture plus bead implantation assays, cell proliferation analyzes combined with different imaging techniques, digital densitometry, therefore we are planning to analyze mouse tooth development using all of these techniques to elucidate how the spatial and temporal expression pattern of these signalling molecules affects epithelial stem cell nice of incisor development. Additionally our aim is to characterize the stem cells molecularly and to develop methods for their isolation. We hope that our findings will have significant implications for organ regeneration and should prove of great interest to scientists in the fields of biology, medicine. The long-lasting benefit of my ERG is to adaptate these mol
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Guiding Language Technology Paths from Research to Markets' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

COMPASS is a Support Action for the Language Technology European research community and industry, that aims to:1.Promote faster, wider and smoother market take-up of Language Technology (LT) research results by facilitating closer collaboration between research and industry players, and by generating better knowledge and understanding of demand/user needs and expectations2.Foster the process of consolidation of LT stakeholders as a self-sustainable and innovative global industry, strategically co-ordinated under a common vision and approach to consumers' needs, and acting upon a shared innovation agenda for the continuous improvement of their technological base.To achieve these objectives, the COMPASS consortium will implement a Support Mechanism structured by two pillars: an LT Innovation Forum to mobilise and coordinate LT stakeholders, and an LT Market Observatory to provide information and insights for better innovation decision-making. These core actions will be complemented by a comprehensive programme of Dissemination and Exploitation of project outputs.Impacts derived from a successful completion of LT COMPASS will be measurable in a number of ways, e.g.: partnerships between research centres and commercial developers/vendors, deployment of LT-enabled products and services, wider awareness and recognition of the current and future potential of LT.