RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Integrating Distributed Applications on the Basis of STEP Data Models' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

STEP (ISO 10303) is the international standard for the exchange of industrial product data. AP214 is a part of STEP for "Automotive Design". It is well suited to be the integration backbone to realize the concept of a "digital factory". Within this project AP214 as well as AP212 "Electrical Installation" will be used for the body in white assembling of cars and the needed production facilities. Data from the engineering, design and try out phase will be integrated in STEP compliant databases and linked with various CAx tools and an EDM system. The data will be made network accessible in read and write mode for various usages and users in parallel. To keep the solutions platform neutral the Java programming language will be used throughout the project. Data formats, suitable for Internet communication such as XML, VRML, Corba/IDL, and Java object serialization will be used to link CAx systems and other end-user tools with the integrated STEP databases. The data will also be made available on wireless handheld devices for end user access.OBJECTIVESThe objective is to integrate and organize the data flow for the planning of production facilities. For this, data, collected at different stages of the design, starting from the requirement phase till the final production shall be integrated in databases, organized according to STEP data models, mainly ISO 10303-214 Automotive Design" and ISO 10303-212 "Electrical installation". Integration mechanisms for existing non-STEP based database architectures and CAx-applications need to be developed. Since customer, designer, manufacturer and installation location are on different places, the integrated data must be fully accessible through networks. For this data must be available in various formats: from worked up HTML/XML represent
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Testing Atmospheric Chemistry in Anticyclones' to be submitted under Fourth Framework.

assistant: **Abstract**

To understand the processes which control tropospheric ozone and oxidation capacity on a regional and global basis.There are still severe limits to our understanding of the processes which control tropospheric ozone and oxidation capacity on a regional and global basis. These limits restrict our ability to address many scientific and policy issues, and the aim of this proposal is to employ a well integrated combination of airborne and ground-based measurements and statistical and deterministic models to resolve some of these.  Amongst these questions are those relating to Global Change, such as: Is the ozone concentration over the North Atlantic significantly enhanced by human-made emissions? Can the ozone balance be predicted? A second set of questions relate to oxidation processes: How many ozone molecules are formed for each NOX molecule converted into products, including organic nitrates? How does this number depend on the concentration of precursors? Can indirect estimates be made of the main oxidant molecule, hydroxyl? A third set relates more closely to policy issues: What are the relative roles of VOC and NOX in forming ozone over the N Atlantic? Are measured concentrations of NOy and hydrocarbons consistent with European emission inventories?  The technique used will be to characterise changes in the chemical compositio of summertime European continental air masses as they move over the ocean, and compare them with our current understanding of chemical processes. The air mass from Northern Europe will be followed as they move over the sea in the lower troposphere on the outer edge of an anticyclone, avoiding areas of cloud and precipitation. Concentrations of ozone, NO, NO2, NOy, PAN, individual organic compounds (including organic nitrates), CO, peroxides and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Models and their Effects on Development paths: an Ethnographic and comparative Approach to knowledge transmission and livelilhood strategies' (MEDEA).

assistant: **Innovation**

The project interrogates the impact of development paths on the livelihoods and life projects of citizens. Starting from the premise that the analysis of (dominant or alternative) development paths must be situated within the complexities of historically unfolding links and realtionships, we shall explore how they are 'practiced' in specific environments. Central questions address: 1) How development models interact with specific socio-economic contexts 2) The effects of these interactions on transmissions and innovation of knowledge/skills 3) How specific development paths affect livelihood strategies.  An interdisciplinary approach combines qualitative research and comparative methodologies with modelling to explore the dynamic effects of development models as they are implemented in specific contexts, at micro and macro levels. We hypothesise that: a) There is a lack of fit between the formal design of development models and their concrete applications. b) The transmission of knowledge/skills is central to effective development. c) Knowledge/skills (both tacit and explicit) are transmitted through formal and informal mechanisms, for example between gender and generations in families and neighbourhoods. d) Political and economic disruptions constitute situations of crisis in this transmission but at the same time afford opportunities for innovation.  Focusing on connections between skills, work and unemployment in relation to heavy industry, the research will identify critical points in the shifts in demand for knowledge across generations, regions and economic spheres. An ethnographic approach enables a detailed account of social networks (encompassing those of solidarity and support) within and beyond work places, including strategic friendship, kinship and neighbou
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Advanced Risk Assessment and Management for Trustable Grids' in the context of a Sixth Framework call.

assistant: **Objectives**

Grid technologies have reached a high level of development, but adopters underline core shortcomings related to security, trustiness, and dependability of the Grid for commercial applications and services. Users require a job execution with the desired priority and quality and negotiate Service Level Agreements (SLAs) to define all aspects of the business relationship. Nevertheless, providers are still cautious on adoption as agreeing on SLAs including penalty fees is a business risk: system failure, operator unavailability etc. can lead to SLA violation. Providers need risk assessment methods as decision support for accepting/rejecting SLAs, for price/penalty negotiation, for activating fault-tolerance actions and for capacity and service planning. Customers - Grid end-users and brokers - need the estimation and aggregated confidence information for provider selection and fault-tolerance/penalty negotiations.<br/>AssessGrid will address the risk awareness and consideration in SLA negotiation, self-organising fault-tolerant actions, and capacity planning. It will develop and integrate methods for risk assessment and management in all Grid layers. The corner stones are risk management scenarios reflecting the perspective of Grid end-users, brokers, and providers. The results will support all Grid actors by increasing the transparency, reliability, and trustiness, as well as providing an objective fundament for planning and management of Grid activities. Thus, AssessGrid will supply Next Generation Grids with additional innovative and required components to close the gap between SLAs as concept and accepted tool for commercial Grid uptake.<br/>The AssessGrid development will be in a Grid standardisation context and will produce generic, customisable, and interoperable ope
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Origami-DNA/AgNCs Sensor for Detection of miRNAs' to be submitted under Horizon Europe.

assistant: **Abstract**

Breast cancer (BC) is a prevalent kind of cancer worldwide and it is one of the primary causes of cancer-related deaths in women. The research has shown that early detection of BC could significantly increase the chances of survival for patients. Recently, there has been a growing interest in microRNAs (miRNAs) as potential biomarkers for the early diagnosis of BC. Therefore, the development of new diagnostic tools for the early detection of BC is necessary. Thus, biosensors based on DNA nanotechnology emerge as a novel, versatile, and easily accessible alternative.In this context, the synergy between the fluorescence properties of DNA/AgNCs and the structural properties of DNA-origami will allow the creation of a new generation of hybrid nanomaterials (nanohybrids), which could be conceived as biosensors for the detection of miRNAs associated to BC with high sensitivity, sequence specificity, high throughput, low cost, and easy access.ODASMIR aims to design origami-DNA/AgNCs nanohybrids (ODAs) to develop a biosensor to diagnose BC through the detection of different miRNAs and, it will validate in in vitro models (2D and 3D). ODASMIR presents a multidisciplinary approach, both the objectives and the experimental methodology are on the interface between biology and chemistry. The biosensors obtained and their validation at the clinical level could have a significant impact on the accurate and early diagnosis of BC representing a significant advance in the field of nanomedicine.


**Keywords:** DNA nanotechnology, Biosensor, miRNAs, Breast Cancer, Fluorescence
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Socially inclusive health care financing in West Africa and IndiaShort title: Financing health care for inclusion' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

Recent health financing reforms in low and middle income countries aim to introduce affordable prepayment and subsidies for low socio-economic groups. However, while such reforms have led to increased utilization of care, often the poor and informal sector continue to be excluded from coverage.Health Inc. puts forward the hypothesis that social exclusion is an important cause of the limited success of recent health financing reforms. First, social exclusion can explain barriers to accessing health care due to disrespectful, discriminatory or culturally inappropriate practices of medical professionals and their organisations, within the context of poor accessibility and quality of care. As a consequence, removing financial barriers does not necessarily guarantee equitable access to care. Second, social exclusion can explain barriers to accessing the health financing mechanism itself. Differential access to information, bureaucratic processes, complex eligibility rules and/or crude and stigmatizing criteria for means testing prevent socially excluded groups from enrolling in financing schemes, even if they are fully subsidised. Social inclusion, by contrast, may explain why more powerful, wealthy and vocal groups disproportionately ‘capture’ the benefits of publicly funded health care.In four countries/states (Ghana, Karnataka, Maharashtra and Senegal), Health Inc. employs mixed methods to analyse whether different types of financing arrangements overcome social exclusion and also increase social inclusion by empowering socially marginalised groups. A multi-sectoral stakeholder analysis will also explore whether vulnerable populations participate in policy making and whether their needs are understood.Health Inc. will compare policies across contexts in order to elicit le
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Establishing the role of Purkinje fibres in the development of arrhythmias for the prevention of Sudden Cardiac Death: Insights from a combined in vivo and ex vivo study' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Sudden cardiac death (SCD) following ventricular fibrillation (VF) is a major cause of mortality in the industrialised world. VF is characterised by chaotic electrical activity in the ventricles leading to severe cardiac dysfunction. Thus far, the underlying mechanisms for the initiation and maintenance of VF are not fully understood. Recent clinical developments in the treatment of VF by the Host’s laboratory have discovered distinct electrical activity associated with a specialised cell-type, Purkinje fibres, which were found to precede the spontaneous beats that manifest VF. Targeted radiofrequency (RF) ablation of these sources has markedly improved treatment and the rates of recurrence of arrhythmias in patients suffering from idiopathic VF. There is also growing evidence that the Purkinje system may be involved in arrhythmogenesis in cardiac pathologies such as myocardial infarction. Therefore, this proposal aims to utilise in vivo electrophysiological techniques in combination with a newly developed ex vivo optical imaging technique on a large animal model (sheep) to determine the roles of Purkinje fibres in the development of life-threatening arrhythmias with a focus on improving the effectiveness of ablation therapies. Furthermore, this approach shall be applied to further investigate a cardiac disease model that is at significant risk of arrhythmogenesis, myocardial infarction. The proposed aims shall be carried out in vivo using MRI and epicardial and endocardial electrophysiological recordings. This will be followed by optical mapping of ex vivo coronary-perfused ventricular preparations providing insight into the 3D organisation of electrical activity. These techniques will provide the appropriate tools for determining the precise location of arrhythmogenic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Promotion of sustainable cherimoya production systems in Latin America through the characterisation, conservation and use of local germplasm diversity', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

Cherimoya (Annona cherimola Mill.) is a perennial fruit tree species of Andean origin of excellent organoleptic qualities and nutritious value. Despite the presence of an enormous wealth of local diversity, limited and often little coordinated activities t o use this potential have been carried out in the Andean region. Through REDARFIT (the Andean Plant Genetic Resources Network), national programs in Bolivia, Ecuador and Peru have identified cherimoya as a priority species for the region and have express ed their wish to strengthen and combine their ongoing activities on this crop. This proposal aims at the promotion of sustainable cultivation of cherimoya in those three Andean countries based on the characterisation, conservation and use of local geneti c resources combining the available European expertise (both at the scientific and at the production levels) with local ongoing activities. Innovative research activities (using molecular tools and Geographic Information Systems) will provide new scienti fic insight into the existing cherimoya diversity providing the necessary information to optimise current germplasm conservation activities. This will allow unlocking the present, but so far untapped, genetic potential of cherimoya and canalise the obtai ned results to tackle the essential constraints (pests, lack of adequate cultural practices and limited commercialisation) for optimal cherimoya cultivation for the end-users, the poor resource Andean farmers. Training of local scientists will fortify the scientific capacity in the region ensuring a long-term impact of the project. The consortium was built based on existing expertise and experiences and comprises 9 partners in 6 countries, including NGOs. This proposal clearly addresses the recommendatio ns of the Con
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'K-Homology and M-Theory physics'.

assistant: **Innovation**

We apply new mathematical tools of certain generalized cohomology theories, namely K-homology and differential cohomology, to study the problem of obtaining realistic four-dimensional backgrounds of string theory suitable for phenomelogical analyses. The consistency conditions implied by the cancellation of global anomalies in string theory are used to establish the conditions under which a given compactification is consistent. Twisted K-theory and K-homology is used to derive an effective action governing the dynamics of little string theory, with an eye to gaining insight into the world volume theory of the M5-brane in M-theory. The gauge theories defined by non-trivial background B-fields are developed and used to study a large N limit of the gravitational sector of string theory such that the limit is precisely M-theory. A crucial ingredient in our construction is the identification of the topological sectors of Type IIA string theory and M-theory with gauge theories based on the rank 8 exceptional Lie group E8.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'DYNAMICS OF THE DURABLE. A History of Making Things Last in the Visual and Decorative Arts.' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Our cultural heritage comprises many art objects that are hundreds, some thousands of years old. How did they survive this long? While many factors determine if and how art can be preserved, one has fundamentally impacted its long-term survival: the desire to make and own artefacts that withstand the test of time. This project—DURARE—will undertake the first comprehensive study of the impact of the artisan and patron’s ambitions to craft, own and theorize durable objects on the long-term development of the visual and decorative arts. To achieve durability, artisans have worked stone and metal, created dyes and pigments thought never to fade, made surface coatings ensuring the protection of more brittle materials, and transformed soft clay into long-lasting ceramics. Patrons coveted physically stable objects; yet stability does not always ensure durability: culturally fragile gold can be melted and re-used. Beyond how the durable was made, DURARE will map the social practices influencing durability. We will also establish how, through artistic and social pursuits for durable art, humans acquired knowledge of the stability and behavior of materials over time, thus impacting knowledge traditions outside art history. Finally, we will elucidate the created practices and institutions facilitating durability, such as cultural heritage conservation and museums. Studying the history of durability in art requires hands-on experience with the materials and processes used to make and explore permanence. This project therefore uses an innovative methodology, combining historical research into art objects and textual sources with hands-on reconstructions of materials and techniques. DURARE will achieve a fundamental understanding of durability in art by charting: 1. Variations and co