RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'FACCE-Evolve - Agriculture, Food Security and Climate Change Coordination and Support Action 2' under Horizon 2020.

assistant: **Concept**

The Joint Programming Initiative on Agriculture, Food Security and Climate Change (FACCE-JPI), launched in October 2010 by the European Council, brings together 21 countries committed to “building an integrated European Research Area addressing the challenges of agriculture, food security and climate change” (FACCE-JPI Strategic Research Agenda). The JPI aims at aligning research programming among its members in the long run, so as to increase the efficiency of research funding, cover gaps, avoid duplications and provide high-level innovative research on the European scene. The FACCE-Evolve Coordination and Support Action is designed to solidify foundations that will ensure long-term durability of joint programming and actions. FACCE-Evolve will thus continue to support the successful development of the FACCE-JPI and allow it to develop a set of means destined to ensure its self-sustainability. The FACCE-Evolve will therefore provide support to JPI members in order to:•Investigate different options for self-sustainability and test the most suitable ones.  •Investigate and develop novel processes and tools to support uptake of the SRA and its updates as well as the bi-annual implementation plans and monitor effective harmonisation, integration and alignment of national research programming, to enable evidence-based policy making and effective cross-policy actions•Implement and oversee the increasing number of joint actions•Pursue ongoing coordination with Horizon 2020 objectives with a scale and scope of action that should go well beyond what either the EU or Member States can achieve on their own•Ensure the perpetuation of an effective, enriching dialogue with European and international stakeholders•Strengthen the international dimension and visibility of the JPI throug
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The role of Chk1 in hair follicle stem cells and skin tumorigenesis' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

We have found that the ablation of Chk1, a serine-threonine kinase that is activated after DNA damage, strongly reduced the formation of chemically (DMBA/TPA) induced skin tumours, thus suggesting a role of this protein in hair follicle stem cells population, from which tumours are thought to arise. We have observed that deletion of Chk1 causes cell proliferation, DNA damage, and apoptosis within the hair follicle, however the populations affected and the order of events in individual cells have not been clearly defined. I hypothesise that Chk1 deletion causes stem cells to enter an aberrant cell cycle which creates DNA damage during replication and consequently leads to cell death. The purpose of this project is to investigate how Chk1 deletion affects the quiescence, proliferation, and survival of hair follicle stem cells, and to use an in vivo chemical genetic approach to determine whether these processes can be manipulated pharmacologically.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'The Sustainable Renovation Hub for Existing Buildings' in the context of a Horizon 2020 call.

assistant: **Objectives**

The 40% of energy consumption and the 36% of CO2 emissions in the EU are produced by buildings. Besides, the 35% of the buildings in the EU are more than 50 years old, and almost 75% of the building stock (15,000,000 buildings only in France) are energy inefficient (Certification levels between E and G). Economie d’Énergie´s (EDE’s) solution (Easy Renovation Hub) is a Hub that guides the customer from the Energy performance determination up to the refurbishment of a house. We provide all the services needed to optimise the energy performance of a house. To optmise the solution, we use a self-learning algorithm developed by the company, based on a Beta version already commercialised in France. The competitive advantage of the Easy Renovation Hub is that it is able to find the best technical solution based on a self-learning algorithm and guides the householder from the beginning to the end, until the optimisation of the energy performance level (A to C).This project will have a Return of Investment ROI of 4.42 by 2023 and we will reach the payback in 2021. Easy Renovation Hub will also have a positive impact regarding employment, as 50 people are planned to be hired.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The biofilm matrix and its functional role in the ecology of bacterial communities' under Horizon 2020.

assistant: **Concept**

Complex microbial communities are comprised of diverse, interacting species. Often, such interactions result in outcomes that cannot be predicted from studies of their individual components in isolation. However, the underlying mechanisms resulting in such community intrinsic properties remain unidentified. The overarching aim of BioMatrix is to identify the molecular mechanisms underpinning community intrinsic properties of bacterial communities.In nature, bacterial communities are predominantly organized as biofilms in which the cells are encased in a self-produced polymeric matrix. I hypothesize that the altered matrix composition of multispecies biofilms is the primary cause of community intrinsic properties defining bacterial communities. BioMatrix will test this hypothesis using expression studies of genes encoding matrix components and functional assessments of gene deletions leading to loss of specific matrix components. These will be addressed in settings of increasing environmental and community complexity, thus ensuring ecological relevance. High-resolution methodologies for single-cell detection will be combined with advanced image analysis to enable crucial micro-scale studies of bacterial communities. New approaches, such as printing 3D leaves suitable for manipulation and microscopy analysis, will be developed and applied to expand exploration to in situ conditions.BioMatrix will close a primary knowledge gap in microbial ecology, by identifying fundamental mechanisms shaping bacterial communities. The impact of these mechanisms for community function and protection will be validated in settings of high community and environmental complexity. This will theoretically and experimentally advance biofilm research, addressing a severe bias towards in vitro stu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Towards a novel paradigm for cardiac function assessment from imaging' in the context of a Horizon 2020 call.

assistant: **Objectives**

Cardiovascular diseases have been defined as a top priority within H2020. Although  diagnostic approaches and therapies have drastically improved over the last decennia, effective, validated and auditable tools for the integrated assessment of cardiac function in clinical practice have yet to be developed. CardioFunXion will contribute to a novel paradigm for integrated assessment, combining (image-based) measurements with (model-based) incorporation of physiological knowledge and clinical guidelines. Project outcomes will include validation (improving reproducibility) and integration (simplifying interpretation) cardiac function assessment tools. These novel approaches will be implemented by connecting the imaging industry with the academic and clinical worlds through a combination of four PhD research projects with dedicated training initiatives to develop an inter-sectorial and interdisciplinary culture. The individual research projects are entitled: Longitudinal assessment of function; Fusion of heterogeneous measurements into physiological plausible representations; Open reference databases/tools for multimodal validation of strain; Novel approach for evidence based classification of heart failure etiologies.The consortium is composed of a large Medical Imaging Company (Philips), a University (UPF), and 2 Clinical Centres (IDIBAPS/CHUC), thus encompassing the whole spectrum of relevant multi-disciplinary multi-sectorial Europe-wide expertise. The early stage researchers in the project will thus benefit from a holistic view of the topic and gain first-hand experience in academic, industrial and clinical research and development.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Warming ocean And Responses of Arctic Marine Mammals' (WARMM), addressing dissemination and exploitation.

assistant: **Impact**

Over the past 30 years, sea ice in the Arctic has declined by 3-4% per decade, making the Arctic the area experiencing the most rapid ecological changes due to climate change. Understanding the consequences of climate change on the Arctic ecosystem is therefore part of the European Unions (EU) wider efforts. As a consequence of rapid sea-ice loss and increasing temperatures, the abundance, diversity and distribution of low trophic level organisms will be inevitably altered, generating cascading effects through the entire marine food chain from phytoplankton to apex predators. Despite their crucial role as bio-indicators of the Arctic marine ecosystem, the capacity of Arctic cetaceans to adjust their behaviour (foraging, movement patterns) and physiology (fat storage, thermoregulation) to climate-induced perturbations remains poorly understood. By compiling a multi-species long-term dataset covering 25 years and including 2 Arctic (narwhal and bowhead whale) and 2 sub-Arctic (humpback whale and harbour porpoise) apex predators, the WARMM project aims at investigating the behavioural and physiological responses of these species to climate change. The choice of the 4 cetaceans is based on their contrasting diet, habitats and level of activity, making this dataset unique to feed a comparative analysis of how these 4 species will cope with an imminent warming ocean. I will exploit a large existing dataset that will be augmented by physiological data collected during the project to (1) identify the foraging strategies from acoustic and accelerometry data, (2) link the behaviours and physiology to the environment, to finally (3) predict the future responses of apex predators in terms of thermal stress and geographical range. Our project will constitute an unprecedented scienti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Electronic transitions and bistability:  states, switches, transitions and dynamics studied with high-resolution X-ray spectroscopy'.

assistant: **Concept**

We propose to study transition metal compounds of uncommon transport properties and excitation characteristics applying emerging high-resolution X-ray spectroscopy. The objective is to determine the microscopic origin of the unconventional behaviour of systems with strong electron correlation through systematic investigations, as well as to reveal bistability conditions and excitation characteristics of switchable molecular systems. The main techniques involved are synchrotron radiation (SR)-based spectroscopies, which can explore the fine details of the electronic structure. Besides using existing end stations of SR facilities, we plan to build a portable spectrometer that can be advantageously used both in a laboratory (e.g., with a radioactive source) and at specially dedicated beamlines of SR facilities, in order to benefit from their specializations in extreme conditions and advanced sample environments, in particular unconventional experiments. This spectrometer should also be able to work in a time-resolved mode so that it could address the dynamics of electronic excitations on the attosecond to nanosecond time scale. The suggested work is expected to push high-resolution X-ray spectroscopies toward maturity, which should open up new horizons in electronic structure and dynamics studies of condensed matter research.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Study of the interaction of the transcription factor stat5 and the sheep ?-lactoglobulin promoter in the context of chromatin' under Fifth Framework.

assistant: **Concept**

The nucleosomes in the sheep ß-lactoglobulin gene promoter are positioned in association with three Stat5 binding sites. We want to study the interaction of Stat5 with nucleosomes during the process of activation of transcription of this gene in the mammary gland.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Bridging effectiveness and sustainability in afforestation / reforestation in a climate change context: new technologies for improving soil features and plant performance' to be submitted under Seventh Framework.

assistant: **Abstract**

The aim of SUSTAFFOR (Bridging effectiveness and sustainability in afforestation / reforestation in a climate change context: new technologies for improving soil features and plant performance) is to conceive, produce, develop and on-field validate novel techniques aiming at improving afforestation / reforestation projects from an environmental, technical and economic point of view, as well as to explore the synergies between them.These novel techniques are:1. MULCHING TECHNIQUES, aiming at reducing the need for weeding and soil water evaporation:1.1. A flexible plate based on a mixture of bio-plastics in a matrix of a woven structure of vegetable fibers.1.2. A mat based on plant proteins and non-woven vegetable fibers.1.3. Different biodegradable mats made of woven and non-woven textiles based on natural fibers, strengthened with bio-resins.1.4. A reusable mat built with recycled rubber (worn-out tires and conveyor belts).2. SOIL CONDITIONERS, aiming at retaining and releasing water available for plants while improving soil structure and fertility. A mix of new generation hydro-absorbent polymers combined with fertilizer and growth precursors.All of them are built in Europe, made exclusively with local materials mainly coming from waste, and are either 100% biodegradable or re-usable inert material.SUSTAFFOR Partnership is:- 4 SMEs producing novel techniques: DTC, La Zeloise, Ecorub (Belgium) and Terracottem International (Spain)- 2 SMEs specialized on commercialization of reforestation and afforestation techniques: Terrezu (Spain, project coordinator) and Ceres (Poland)- 4 RTDs with different specializations: Forest Sciences Center of Catalonia (Spain, scientific and technical conception and design of afforestation and reforestation and soil sciences); IC2MP - Environ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Looking for Historical Queerness in the Slavic-Speaking Dinaric Mountains' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The project analyzes gender and sexual diversity in the Western Balkans right before the intense modernization of the 20th century. By examining written historical sources, the project sheds a new light on the life and everyday practices of regional gender non-binary people (tobelijas) or same-sex-loving individuals (male pobratimi and female posestrime). Both phenomena were extensively written about in early South Slavic ethnographies without references to their sexuality, sex, or gender. Due to the inability to obtain oral sources, and the ideological framework through which early researchers rendered their subjects heterosexual or invisible, the project establishes a two-tier hypothesis supported by two sets of archival sources. Without engaging the modes of early modern knowledge production in written sources, it is not possible to explore the existence and everyday practices of gender non-binary or same-sex-loving individuals before modernization. By using a contemporary theoretical framework from gender and queer studies, historical anthropology, and postcolonial studies, the project will analyze early Slavic ethnographic materials to identify cases of tobelijas and pobratimi/posestrime. The cases will be further explored using regional archives to reconstruct the everyday realities of individuals. In addition to disseminating project results via channels that reach specific disciplines, communication will target the societies researched (Croatia, Bosnia and Herzegovina, Montenegro, and Serbia) to shed light on local traditions in which queer individuals were visible and respected community members. Training through research will provide the research fellow with experience in advanced analysis of written sources (provided by the host institution), with a two-way t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Biological and Mathematical Basis of Interaction Computing' (BIOMICS).

assistant: **Innovation**

Interaction Computing (IC) takes inspiration from cellular processes rather than from evolution. BIOMICS aims to leverage existing cell metabolic and regulatory mechanisms as the ontogenetic basis of a model for IC. However, because the knowledge to properly mimic, exploit and adapt these systems to computer science is lacking, BIOMICS will also advance the state of the art in the mathematics of biocomputing. The mathematical structure thus uncovered feeds into two different and complementary directions. On the one hand, it will inform the automata theory formalisms for IC; on the other hand, it will be mapped through category theory to the logic foundations of the BIOMICS specification language. Whereas the automata theory research will focus on the structural properties of self-organising systems, the BIOMICS specification language will instead focus on the specification of self-organising behaviour. By end of Year 2 we will have developed the formal tools and frameworks from both points of view of the behaviour-realisation dichotomy to be able to effect their synthesis in the form of an environment which, through interactions, is capable of generating useful software systems that match the biological structure template – and are therefore themselves based on interactions. This foundational mathematical work of BIOMICS will be applicable to software systems of a radically new kind and to systems biology, creating a unified mathematical framework for understanding, predicting, manipulating, and dynamically synthesising algorithmic activity-in-context based on interactions (i.e. interaction computation) in both realms. This will be demonstrated not only by the application of the framework to the analysis of complex-adaptive biological systems beyond those studied in the