RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Multimaterial airframes based on 3D joints between AM metals and carbon-fiber composites', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The aim of MIMOSA Project is the development of joined multi-material structures with new concepts able to exploit the digital and hybrid processes in order to achieve higher technological and economic performances with respect to current traditional joints. Furthermore, MIMOSA will lead to the application of circularity of materials and production by integrating the recycling, starting from the ideation phase of product and business. These ambitions and associated needs will be achieved with innovative technology and competitive process for multi-material joints between AlSi10Mg alloy for additive manufacturing (AM) and composites (CFRP, carbon fiber-reinforced polymers). The project proposes new joint concept design, after-service materials regeneration (50% of metals and 90% of CFRP), weight (-51%) and lead time (-65%) reduction and overall process environmental footprint reduction. A prototype of vertical stabilizer (VS) structure will be fabricated and analyzed as the business case of the Project. At the end of the Project, TRL6 is expected by starting at TRL3. Many aerostructures are composed of CFRP skin and metal parts coupled by rivets. However this kind of joint shows some drawbacks: (1) long time for assembling, (2) loss of fibers integrity due to rivet holes, (3) rivets payload, (4) joint surfaces treatment with paints needed, (5) rivets failure issues, (6) hard inspection and maintenance of rivets. MIMOSA Project will go beyond the state of the art in building aircraft structures by providing: (1) scientific research-driven integration of different design fields and fabrication processes, (2) new AM-CFRP multi-material joint concept, (3) reduced waste of materials thanks to recycling and associated economic value generation, (4) enhancement of process perfo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Origin of Magnetic strUctureS in the ISM obscuring the Cosmic DAwn' to be submitted under Horizon 2020.

assistant: **Abstract**

MUSICA will orchestrate an MSC-Action where the deepening of our knowledge of the local Universe will play together with unveiling the cosmic dawn. We will focus on the origin of new structures, stains, in the diffuse Galactic interstellar medium (ISM) recently revealed by the LOFAR radio telescope and model their contamination to the observations of the Epoch of Reionization. The study of the diffuse ISM is key for pivotal astrophysical problems, such as the inefficiency of the star formation process. The ISM fills the Galaxy with cosmic rays, multiphase gas, and dust particles, all coupled with magnetic fields. It is through their interactions that a complex cycle, involving phase transitions, magneto-hydrodynamic (MHD) turbulence, and gravity, is expected to convert diffuse/warm matter into denser/colder regions, where stars form at a rate of only a few solar masses per year. In theory, magnetic fields in the ISM may explain such low star-formation rate. In practice, characterizing magnetism at the starting point of this cycle of matter has been a difficult observational challenge until now. Today, the Planck satellite and LOFAR are unique complementary datasets to investigate phase transition between warm/ionized and atomic magnetized ISM. MUSICA proposes an unprecedented joint analysis of the Planck/LOFAR data with the best-available kinematic data of the atomic and ionized hydrogen to investigate the MHD origin of the stains. By comparing observations with synthetic data from state-of-the-art MHD simulations of the ISM, MUSICA will (1) significantly advance our knowledge of structure formation in the diffuse ISM and (2) prepare foreground analyses for future cosmological probes, such as LOFAR and the SKA radio telescopes. Hence, funding MUSICA will allow partners
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Three dimensional structure, dynamics,and function of calcium release channel resolved by combining three novel microscopical techniques' (1994-1998).

assistant: **Concept**

We propose to develop an integrated microscopical approach to probe structure-function relationships of large uncrystallised macromolecular assemblies of high resolution. We aim at elucidating both the structural and the functional aspects of the molecules at the resolution level of 12 nm. Our problem-oriented methodology development is directly supported by the availability of recombinant protein (in its wild type and in mutated forms). Our test system is the type 3 isoforrn of the ryanodine receptor calcium release channel family. The integrated approach synergetically combines: 1) Three-dimensional (3D) cryo-electron microscopy of single macromolecules embedded in vitreous ice using the angular reconstitution" method [Serysheva et al., 1995]. One objective is to push the attainable resolution to the 1 nm level, which resolution is feasible [R. Henderson, Quart. Rev. Bio phys 28 (1995) 171-193]. A Simple Super Computer (SSC) consisting of an array of Pentium-based computers (to be programmed by subcontractor Image Science Software GmbH) will provide the necessary computing resources. 2) Molecular Recognition Force Microscopy (MRFM, Hinterdorfer et al., 1996). Atomic force microscopy (AFM) [Z. Shao, J. Yang, Quart. Rev. Biophys 28 (1995) 195-251] is combined with molecular recognition by attaching an antibody to the AFM tip via a flexible linker molecule. This novel type of scanning probe microscope will be used to map antigenic sites in the RyR3 protein. 3) Single Dye Tracing (SDT, Schmidt et al., 1995) for time-resolved (ms range) imaging of single fluorescent molecules (label on antibodies against RyR3 in this proposal) within a membrane. This technique can be combined with the patch-clamp techniques which combination allows the measurement of the functional activit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Silicon-based nanostructures and nanodevices for long term nanoelectronics applications' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

NANOSIL Network of Excellence aims to integrate at the European level the excellent European research laboratories and capabilities in order to strengthen scientific and technological excellence in the field of nanoelectronic materials and devices for terascale integrated circuits (ICs) and disseminate the results in a wide scientific and industrial community.NANOSIL will explore and assess the science and technological aspects of nanodevices and operational regimes relevant to n+4 technology node and beyond. It will provide a forward-look for the industry, enabling informed decisions to be taken on technology development in order to speed up technological innovation. It will encompass flagship projects on nanoscale CMOS and post-CMOS. The activities will thus be centred on the More Moore" and "Beyond-CMOS" domains but natural links will also been established with the other ENIAC areas. Within the Network there are all the critical facilities and expertise to occupy and transcend this space. We will propose innovative concepts, technologies and device architectures- with fabrication down to the finest features, and utilising a wide spectrum of advanced deposition and processing capabilities, extensive characterisation and world leading device modelling. This work will be carried out through a network of joint processing, characterisation and modelling platforms. The consortium will work closely with and take steering from European industry. It will feed back data and know-how on materials and devices that deliver the required performance. This critical interaction will strengthen European integration in nanoelectronics, help in decision-making by industry and ensure that Europe remains at the forefront of nanoelectronics for the next 2 – 3 decades."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Unmet MAGnetic properties in micro and nano-particles by synthesis through gas-diffusion electrocrystallisation (GDEx)' in the context of a Horizon 2020 call.

assistant: **Objectives**

Memory storage is a defining component of modern computing. It is a key issue because it determines system costs and power consumption. The ability to increase memory storage relies on the discovery, understanding, and improvement of new memory-storage materials. Recently, a third fundamental state for magnetism was experimentally realized in a novel class of matter: the spin-liquid state, after finding a way to synthesize herbertsmithite which is now prospected as a promising memory-storage material. Hydrothermal methods to grow herbertsmithite are available, but they have low production rates and yields and focus on the production of macroscopic crystals, while it is known that nano-scale dimensioned particles do have superior or different properties. Using heterogeneous (electro)catalytic routes, the main problems of the thermal synthesis can be solved. Gas-diffusion electrocrystallization  (GDEx) is a new electrochemical process developed at the host organization. It is a rapid one-pot reaction crystallization process, electrochemically steered at the three-phase junction of a porous gas-diffusion cathode. The main objective of this project is to develop, optimize and validate the GDEx technology for the bottom-up synthesis of micro and nano-scaled Zn4-xCux(OH)6Cl2 particles. The project aims to obtain single-phase (pure) herbertsmithite and its polymorphs via GDEx, understanding the mechanism of formation. The project also aims to obtain these materials as solid particles, colloidal dispersions, and thin films, all with preciselly-controlled properties which can result in tailored magnetic functionalities that may result in revolutionized memory storage possibilities. Furthermore, it is aimed to obtain these particles in gram-quantities per day and at least 70% yie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Impact of Cyclin A2 Deregulation in mouse physiology, cellular transformation and cancer' (2002-2006).

assistant: **Innovation**

The cell cycle is a complex process that is highly regulated by cyclin-dependent kinases (CDKs). CDKs function at different phases of the cell cycle and are regulated by their association with specific cofactors, the cyclins. Different cyclins exhibit distinct expression patterns that contribute to the temporal coordination of each cell cycle event.Two forms of cyclin A exist in mammals. Cyclin A2 is ubiquitously expressed, and activates CDK2 or CDK1 kinases to promote both S phase progression and G2/M transition, respectively. In contrast, cyclin A1 pairs with CDK1 only, and is present in germ cells undergoing meiosis in the testis.The essential role of cyclin A1 in meiosis was confirmed by the observation that cyclin A1-deficient male germ cells arrest a t the G2/M transition of meiotic prophase I and exhibit some apoptotic phenotypes. Cyclin A2 whose expression is more ubiquitous, is essential for embryonic development, the null embryos dying at around day 5.5 pc.This early embryonic lethality has prevented the elucidation of cyclin A2 function in whole mammalian organisms. In order to address the physiological role of cyclin A2 in mammalian growth and health, we will generate mouse models with tissue-specific and/or time-specific inactivation of cyclin A 2.This mouse model will serve as natural readouts of the regulation and function of cyclin A2 in life and growth of a mammalian organism, and will provide several useful cellular models for cell cycle studies. Cyclin A2 over-expression causes premature cell cycle entry into the S phase and over-expression of cyclin A2 was shown to promote cellular transformation.However, the precise role of cyclin A2 in the cell transformation process, and in the development of cancer is not known. We wish to address the impact of c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Wireless Sensor Network Testbeds', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The aim of this project is to provide a multi-level infrastracture of interconnected testbeds of large-scale wireless sensor networks for research purposes, pursuing an interdisciplinary<br/>approach that integrates the aspects of hardware, software, algorithms, and data. This will demonstrate how heterogeneous small-scale devices and testbeds can be brought together to form well-organized, large-scale structures, rather than just some large network; it will allow research not only at a much larger scale, but also in different quality, due to heterogeneous structure and the ability to deal with dynamic scenarios, both in membership and location. <br/>For the interdisciplinary area of wireless sensor networks, establishing the foundations of distributed, interconnected testbeds for an integrated approach to hardware, software, algorithms, and data will allow a new quality of practical and theoretical collaboration, possibly marking a turning point from individual, hand-tailored solutions to large-scale, integrated ones.<br/>For this end, we will engage in implementing recent theoretical results on algorithms, mechanisms and protocols and transform them into software. We will apply the resulting code to the scrutiny of large-scale simulations and experiments, from which we expect to obtain valuable feedback and derive further requirements, orientations and inputs for the long-term research. We intend to make these distributed laboratories available to the European scientific community, so that other research groups will take advantage of the federated infrastructure.<br/>Overall, this means  pushing the new paradigm of distributed, self-organizing structures to a different level.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Can biomechanical measurements of joints predict severity of osteoarthritis?' under Seventh Framework.

assistant: **Concept**

Osteoarthritis (OA) is a painful and disabling, multi-factorial disease with strong genetic and environmental determinants. The natural form of OA that arises spontaneously in Str/ort mice has been used as a model for human OA joint degeneration. This model is limited, however, because it is impossible to grade OA incidence and severity non-invasively in mice. Locomotor biomechanics provides a unique tool for non-invasively assessing knee dynamics, and has already been used to detect gait modifications in humans. Such gait analyses are directly transferable to mice. Our pilot data suggest that OA-prone Str/ort mice, in which the joints deteriorate rapidly with ageing, can readily be categorised by temporal changes in gait. Our hypothesis is that deterioration or deviation in individual mouse gait from normal will provide a non-invasive measure of joint degeneration.Our first aim is to examine the heritability of histological osteoarthritis (OA) severity and drop-out age, and their genetic and phenotypic correlations. Our second aim is to assess the relationship between different aspects of gait measurements and OA severity in Str/ort mice, and to assess the predictability of gait measurements on drop-out age. The third aim is to assess the degrees of asymmetry of individuals’ gait measurements (left versus right and front versus rear limbs) during the development of OA in Str/ort mice and compare these to changes in gait during normal healthy ageing in non OA-prone, mice.Identifying new statistically-defined and robust methods of OA detection in the mouse that do not require sacrifice would radically change how OA research might be conducted using this species and accelerate translation of new therapies.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Integrated quantum correlation counter' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Quantum correlation measurements are essential to study and analyze the statistics of light fields, to observe quantum entanglement and are central in several emerging applications of quantum optics such as quantum cryptography, ballistic imaging, logic gates, quantum repeaters, fluorescence correlation spectroscopy and optical tomography. The measurement techniques have not evolved much since the report of the first quantum correlation measurement in 1956: macroscopic optical elements are used to divide a light beam and single photon detectors are placed in each arm, correlations among the detectors signals are then analyzed to yield correlation histograms. This implementation is bulky and prone to misalignment, when measuring higher-order correlations, the number of required components scales up exponentially. My ERC consolidator grant involves performing numerous quantum correlation measurements on light fields generated by single quantum dots coupled to atomic vapours. Here, a new architecture for a quantum correlation counter is proposed where the detectors are all integrated on a chip to offer the user a compact and robust device to measure quantum correlations up to orders as high as 4 and also able to resolve photon numbers with high fidelity. Eight contiguous superconducting single photon detectors coupled to an optical fiber will be used to achieve high detection efficiencies and unprecedented time resolution. Two prototypes of increasing complexity will be built and tested. The final system will form the starting point for a commercialization effort to be led by Single Quantum BV, a spin-off from my research group that produces single photon detectors. I expect an initial sales volume of 10 units/year to grow to 50 units/year after 5 years.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Network of mobility centres of the Universities of Saarland, Luxembourg, Lorraine and Liège' (UNI-SALLL), addressing dissemination and exploitation.

assistant: **Impact**

Ensuring mobility in a cross boarder area is not easier than elsewhere. Nevertheless the geographical proximity is an asset to allow the building of multicultural experiences at lower human and financial cost. The Great Region has already a practice of cooperation among universities. Mobility centres in this area have been set up at different times thus having various levels of experience and expertise. Through benchmarking, exchange of good practices and experience, the 4 Mobility centres intend to develop concrete tools at the service of the mobility of researchers: FAQs, presentation of the different contexts, assessment questionnaire. Short stays in another Mobility centre will allow training and benchmarking, a standardized report will ensure the sharing of experiences. Providing an opportunity of contact between PHDs and their promoters will contribute to the setting up of an international PHD college. Finally the tools and practices will be exposed to the whole ERA more network in a didactical way.