RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'U snrna export in vitro from synthetic nuclei' under Fourth Framework.

assistant: **Concept**

Research objectives and content To study nuclear RNA export, an in vitro approach is proposed based on the assembly of synthetic nuclei in Xenopus egg extracts. These nuclei are functional for protein import, they transcribe the intranuclear U1 snRNA reporter gene and they actively export the RNA. The aim is to elucidate the mechanism by which the cap binding complex (CBC) mediates U snRNA export and to identify putative other factors involved. Affinity purified antibodies raised against CBC will be used in this system to inhibit export directly and to immunodeplete extracts for CBC. Mutant versions of recombinant CBC will be added to the depleted extracts in an attempt to determine the region of CBC that is required for export. Additionally, extracts will be biochemically fractionated in order to identify other factors involved in snRNA export. A similar approach will be used to study nuclear export of different classes of RNA. Training content (objective, benefit and expected impact) In Dr. Mattaj's lab there is a lot of experience and knowledge about nucleocytoplasmic transport and many recombinant (mutant) transport factors are available. With the described project I could profit from this and learn new techniques (e.g. expression/purification of recombinant proteins, chromatography) and extend my knowledge in the field.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'New crisis and old mysteries: Resolving cosmic tensions to reveal the dark sector', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

It has recently been established that the current expansion rate of the universe (i.e, the Hubble constant) as measured by local probes is discrepant at 5σ with that predicted in the standard Λ cold dark matter (ΛCDM) model calibrated onto cosmic microwave background (CMB) data.  Additionally, analyses of the latest galaxy weak lensing surveys find an amplitude of density fluctuations on large scales (the S8 parameter) that is about 2−3σ lower than what is predicted in ΛCDM. This growing “crisis” is potentially the first indication of a departure from the ΛCDM model, giving hopes to access the fundamental properties of the mysterious dark matter and dark energy that pervade the universe.  On the one hand, I have shown with my colleagues that the “Hubble tension” could indicate the presence of new physics in the  era  pre-recombination,  potentially  connected  to  new  dark  energy  properties  at  early  time.   On the other hand, the “S8 tension” can be connected to new dark matter properties, and in particular could indicate that dark matter is not stable on cosmological timescales, or interacts with some new light species.   Yet,  none  of  the  suggested  models  have  been  robustly  detected  nor  are  they  able  to explain simultaneously the Hubble and S8 tensions.  With the support of the ERC, I will build a group that will develop public tools to firmly identify the new physics mechanism required to explain these cosmic tensions, assess the observational consequences for a wide variety of observables, and the implications for the nature of dark matter and dark energy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Assessing sensitiveness to transport' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

ASSET addresses Task 6: Transport related sensitive areas, Section 3.2 of the SSP 5A call. It will develop the scientific and methodological capabilities to implement European policies aiming at balancing the environmental protection of Sensitive Areas (SA) with the provision of an efficient transport system. Special emphasis on market based instruments. Main impact: improved policy formulation/implementation (infrastructure charging, sustainable development of TEN-T).Main outputs:- common framework of definitions, criteria and valuation parameters for Transport Sensitive Areas (TSA),- methodology for assessment of sensitiveness in TSA,- mapping of TSAs across the EU,- review of policy instruments for the protection of SA, analysis of applicability to different TSA categories, identification of policy packages,- detailed assessment of proposed methodology and policy instruments for 10 case studies (mountainous, urban/metropolitan, natural/protected, coastal areas)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Development of Creep Crack Growth Testing and Data Analysis for Welds' to be submitted under Fourth Framework.

assistant: **Abstract**

This proposal is aimed at standardising creep crack growth (CCG) testing and data analysis techniques for weld metals of interest to high temperature plants The only existing CCG standard (ASTM E-1457) covers testing and analysis of 'parent' metals. However, in practice cracking and failures in industrial components occur more frequently in welds and associated heat affected zones. The testing and analysi techniques for welds require special consideration because of their limited ductility and deformation zone size associated with defect incubation and propagation. The proposal envisages testing welds and HAZs in 2.25Cr IMo and Grade 91 materials, both of which are used in high temperature plant components such as piping, headers and pressure vessels. The former is one of the most commonly used material for high temperature applications while the latter represents a high strength material with potential application for new advanced plant designs and as a replacement material for cracked components in existing plant. At present, in CCG testing in general various testing and data analysis techniques are used by different organisations which result in a large degree of laboratory to laboratory scatter giving less than satisfactory life predictions even for 'parent' materials. The situation is worse for welds and associated HAZs. The objective of this proposal is to standardise these techniques for weldments of interest to European industry and draw up a Draft European Code of Practice.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Advanced Networking for Nuclear Education and Training and Transfer of Expertise'.

assistant: **Concept**

The present situation of nuclear energy in Europe asks for a continuing effort in the field of Education and Training aimed to assure a qualified workforce in the next decades. In this scenario, the present proposal is aimed at enhancing and networking the Europe-wide efforts initiated in the past decades by different organisations belonging to academia, research centres and industry to maintain and develop Education and Training in the nuclear fields. This will allow consolidating, developing and better exploiting the achievements already reached in the past and to tackle the present challenges in preparing the European workforce in the nuclear fields.The main objectives of the proposal are:1. SURVEY AND COORDINATION OF NETWORKING IN E&T AND VET IN THE NUCLEAR AREAS2. DESIGN AND IMPLEMENTATION OF COORDINATED E&T AND VET EFFORTS (Master and Summer Courses for continuous professional development)3. GENERATIONAL TRANSFER OF EXPERTISE (Sustainable production of educational material)4. CROSS BORDER TRANSFER OF EXPERTISE (Implementation of ECVET based exchanges among industrial bodies)5. REINFORCING ETI ACTIONS FOR SHARING AND ENHANCING NUCLEAR SAFETY CULTURE COMPETENCE6. FACILITATING THE NUCLEAR TRANSITION IN FUSION: COORDINATING THE E&T ACTIONSThe European Nuclear Education Network (ENEN), as coordinator of the proposed action, together with the other Participants, is committed to pursue the above objectives, being fully coherent with the ones  suggested in the call (NFRP10) and proposed by the SET Plan Roadmap for Education and Training for the nuclear sector, tightening at the same time the links among the different nuclear areas and better coordinating their contributions in the E&T fields. Strict links with the SNE-TP; IGD-TP and MELODI platforms and other relevant ass
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Tropical forest soils and climate change: A source or sink for atmospheric carbon?' (GLIMPCARBON) targeting Sixth Framework.

assistant: **Abstract**

The response of tropical forest ecosystems to global climate change and elevated atmospheric carbon dioxide levels remains poorly understood. Despite the important role of tropical forest soils in the global carbon cycle, estimates of the carbon sequestration potential of tropical forests are based primarily on estimates of aboveground production and biomass, because little is known about belowground carbon cycling and how it may be affected by climate change. Primary production in some tropical forests has increased during recent decades, prompting speculation that this will boost carbon sequestration.However, this response is likely to be limited by nutrient availability. Importantly, greater inputs of readily degradable carbon in leaf litter may accelerate the decomposition of stable soil organic matter, which would greatly reduce the value of the soil as a carbon sink. Improved understanding of the belowground components of the carbon cycle and their interactions with aboveground processes is required to accurately assess the carbon sequestration potential of tropical forest ecosystems.This project combines litter addition, litter removal, fertilization, and root exclusion treatments to quantify the relative contributions of roots, microbes, and leaf lit ter to soil carbon dioxide efflux. The fate of carbon inputs from decomposing leaf litter will be determined by adding litter that is naturally labelled with 13C and analysing microbial biomass, microbial functional types and soil leachate.Changes in soil organic carbon composition will be assessed directly using state of the art nuclear magnetic resonance spectroscopy to detect functional groups representing stable and labile structures. The results will provide key information on the response of tropical forest so
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'JOS, the first electrified Energy Surface with high efficiency, high power and high energy savings for the wireless charging of all low voltage devices.' to be submitted under Horizon 2020.

assistant: **Abstract**

JOS is the first Energy Surface with high-power and energy efficiency, a patented lighting and charging device system. It’s alow-voltage electrified panel, on which it’s possible to feed any electronic device without any cables, in numberless positionand with an energy saving of up to 25% compared with traditional systems.JOS can also be powered with direct photovoltaic and it’s extensible in series even on very large areas, so to use a singlepower supply and protect the environment.All spaces fed with JOS will enjoy a strong reduction of electromagnetic emissions. The panel has the virtue of thermalinsulation and sound absorption, exploitable in the context of inner installation.JOS technology offers a very different technology and is characterized by: INTEGRATION of all types of devices, HIGHPOWER (100 W per connection), FLEXIBILITY in positioning (table, wall, ceiling), ENERGY SAVING, CUSTOMIZATION(functional and design).JOS is not just a product but a technology with a double value proposition, both B2C and B2B. JOS B2C - ConsumerElectronics, huge market. PLUS: integration, savings, flexibility, elimination of wires.JOS B2B - Great alternative or integration to traditional installation - panels of custom formats, extensible in series withspecific devices. PLUS: reduction of time and costs in all phases, no longer traces or wiring, or structural interventions forchanges, electromagnetic healthiness, energy saving.A technology adaptable to many different contexts, including disability, multiplying and simplifying the access to energy, witha strong facilitation of social and working conditions.Because JOS is a system with many possible applications, the feasibility study will be particularly aimed at the study ofvarious business models, according to the different conte
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Late Stage Fluorination and its Applications to Drug Discovery' (FLUDD).

assistant: **Innovation**

All of modern medicine is dependent on advances in chemistry and the healthcare goalposts have moved as the century has progressed. The pressing need to shorten cycle times and reduce the costs of drug discovery has led pharma and the clinicians that guide them to use scanning techniques such as positron emission tomography (PET), enabling them to increase disease understanding, study target engagement with therapeutics and improve decision making, so that only the best candidate molecules progress to the later stages of drug development. Overcoming these challenges requires multidisciplinary knowledge, and can be facilitated through stronger links between academia and Pharma. Chemical entities substituted with fluorine or fluorine-containing groups are frequently used to design drugs with improved pharmacological and pharmacokinetic profiles that provide important benefits over existing therapies, such as superior safety, efficacy, dosing, and patient compliance. Furthermore, 18F is often selected as the preferred positron-emitting isotope for the labeling of PET tracers due to its advantageous properties. The scientific objective of  FLUDD is to develop novel late stage fluorination chemistry to populate the chemical and radiochemical space available for drug discovery with a focus on novel fluorine-containing fragments, molecules and biomolecules that are not directly accessible from commercial sources or the scientific literature. These novel methodologies will be applied to drugs and diagnostics discovery using both small molecules and proteins. The educational objective is to train the next generation of doctoral scientists in the practice of chemical synthesis and radiochemical methods with an in-depth appreciation of their applications in medicine. FLUDD objecti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Mobile Assistance for Groups  Individuals within the Community - STROKE REHABILITATION' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

MAGIC Post Stroke Project Team has united members from across Europe, dedicated to enable significant change in the delivery of health & social care (H&SC) services for patients post stroke. The consortium has recognised a significant gap in care associated with the recovery of such patients & we need a new way of meeting the needs of 508,000 new post stroke EU citizens/ year. Demographic changes are such that H&SC systems are failing to keep pace with demand & are not fit for purpose. By working in new ways & by reengineering systems with novel innovative technology & solutions we can think differently about our approach to care & improve the well-being for our patients; optimising the opportunity for recovery post stroke. Presently 1/3rd of all stroke patients are discharged from hospital with a significant change to life style, well-being, health status & independence. Community H&SC services do not enable patients to make a sufficient recovery post stroke. A search of state of the art technologies indicated much progress in the development of technologies to assist patients but no system is available to significantly affect rehabilitative improvement to scale; with no solution integration with H&SC services. Therefore, Public Procurers cannot go to open tender to deploy effective technology to solve system failures. The MAGIC Consortium recognised Pre-Commercial Procurement (PCP) as the only way to stimulate the market to find a solution to our common problem. MAGIC is an essential & strategically critical programme for the Team to optimise a patient’s recovery, to modernise H&SC systems to meet demand & to stimulate research, development & innovation. MAGIC will also stimulate European industry to become a global leader in this innovative field. Use of PCP is of pa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Ultra-efficient and stable perovskite tandem solar cells for extreme conditions in space' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

INPERSPACE focuses on an emerging but extremely urgent challenge in Europe: meeting the sharply increasing demand for space-grade photovoltaics (PVs) due to the recent privatization of the space industry. Today’s modern III–V/Ge-based PVs fall short of answering this demand as the new space era requires cost-effective and high-speed processable PVs, on top of the existing high power density requirement. All-perovskite tandem PVs are excellent candidates fulfilling all these requirements. However, their stability must be ensured under ‘synergistic extremes’ from ground to orbit deployment such as high vacuum, particle radiation, high ultraviolet light, frequent temperature cycles (in orbit), vibrations (in flight), and humidity (before lift-off). Unless these concerns are addressed, we risk substantially underutilizing the emerging space technologies in the new space era.INPERSPACE aims to realize this with two core pillars: 1) creating ultra-efficient (>30% at space spectrum) all-perovskite tandem solar cells on lightweight substrates; 2) investigating the fundamental failure modes of these devices under synergistic stressors typical of the extreme space environment, focusing on combinations of stressors with thermal cycling as the most decisive, yet frequently overlooked, stressor for stability in space. I will achieve these goals by i) creating new perovskite compositions to eliminate the performance losses, ii) elucidating the origin of the instability of the devices from nano to macroscale and module level, iii) implementing groundbreaking methodologies to solve stability issues.INPERSPACE is an exceptionally timely and exciting research project. The created knowledge will immediately revolutionize the space PV market and set the agenda in other domains such as pero
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Robl (synchrotron radiation beamline for radiochemistry and material resaerch)' (ROBL) under Fifth Framework.

assistant: **Objectives**

Description:The Rossendorf Beamline (ROBL) is a synchrotron radiation beamline located at the bending magnet port BM20 of the European Synchrotron Radiation Facility (ESRF) in Grenoble, France. The two alternatively operating experimental end-stations are dedicated to radiochemistry (RCH) and materials research (MRH). The RCH allows performing X-ray absorption spectroscopy (XAS) experiments on solid and liquid samples containing radionuclides, in particular actinides, with a maximum activity of 185 MBq. Depending on their concentration, the XAS measurements can be done in transmission or fluorescence modes. Several sample holders and a helium cryostat for low-temperature measurements are available. Certain chemical sample manipulations are possible inside the glove box before or during the XAS measurements. In Europe, ROBL is the only end-station dedicated to XAS experiments (EXAFS/XANES) on radioactive samples. In MRH, a high-duty six-circle goniometer allows performing X-ray diffraction studies on thin films, powders or liquids as well as reflectometry experiments. Special sample chambers (in situ magnetron sputtering, high temperature) with a weight of up to 15 kg can be mounted at the goniometer.Application:Beam time applications must be submitted electronically (see http://fz-rossendorf.de/LSF-ROBL/ari_robl_application.html). The deadline for the current call is April 30, 2002Project Manager:Dr. Norbert Schell, ROBL-CRG at ESRF, B.P. 220, F - 38043 Grenoble Cedex, FranceTel: +33-4-76882367Fax: +33-4-76882505E-mail: schell@esrf.fr