RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Sustainable Surface Technology for Multifunctional materials' under Sixth Framework.

assistant: **Concept**

Biomaterials and drug delivery systems are complex composite systems, often made by applying organic solvents and additives, which have well-known disadvantages like toxicity and flammability. Furthermore, with increasing materials complexity and size red uction to nanoscale, classical solvent approaches are destructive because the used liquids destroy the functional surfaces they are helping to create, due to viscosity and surface tension. Technology based on supercritical carbon dioxide (SCCO2) is an a lternative to overcome the problems associated with the use of traditional solvents. SCCO2 is a non-destructive solvent adequate to manipulate complex functional materials and nanostructures. Furthermore, the technology allows obtaining end-products free of residual solvents. SCCO2 technology is proposed here for the production of a great range of knowledge-based multifunctional materials with better control of surface properties and purity, and for the industrial - high-rate, high-volume - fabrication of surface hybridized or composite materials. The project is centered in pharmaceuticals (drug delivery and targeting with biomacromolecules), biomedical (tissue engineering) and cosmetics (ointmers) products prepared using this technology. Moreover, tech nology transfer to the plastics and fillers industries is addressed.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'A SUSTAINABLE PROTECTION AGAINST WESTERN CORN ROOTWORM' (CORNPROTECT) targeting Horizon 2020.

assistant: **Abstract**

The Western Corn Rootworm (WCR) is a pest that has turned into a major threat to Europe’s corn production. WCR hasspread to most of South East and Central Europe, affecting now 7 million hectares (37% of the European corn cultivation).With an average yield/hectare of €1,800 and damage potential between 20 and 80%, possible yield losses amount to€2,52-10,08 billion.After the ban of the highly toxic neonicotinoids within the EU, there is currently no effective protection against the WCR. Dueto a lack of other solutions, today some unspecific chemical pesticides are marketed and used against the WCR with verylimited effectiveness. To make it worse, these products are toxic and harmful for the environment and for beneficial insects(like bees).LITHOS has developed and patented CORNPROTECT, a biological and highly effective solution for protecting corn againstWCR. It works target specific due to the release of the specific pheromone of the WCR. As a natural solution it is absolutelynon-toxic and harmless for all other organisms and the environment. The specific combination of the pheromone and ahighly porous mineral (zeolite) as a carrier allows a slow release of the pheromone and mating disruption over the activeperiod of WCR adults. It’s also easy to use and affordable (costs to farmers are € 50/hectar, similar to conventionalsolutions). CORNPROTECT can be used in conventional and organic farming.The main objective for LITHOS in this phase 2 project is to bridge the remaining gap to commercial deployment byoptimizing the current formulation, registering CORNPROTECT as EU plant protection product, scaling up existingproduction, and validating the product in the EU market.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'European emigration governance - emigration and diaspora policies and discourses in the post-crisis era', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The project breaks new ground in the study of migration governance by looking at the so-called immigration countries from the perspective of emigration governance. The main underlying theme of this research is that emigration and immigration are two sides of the same coin and thus European migration governance should be approached from two angles to understand its full dimension.European Union is in fact still a region of emigration, with majority of flows staying within its boundaries, but important numbers leaving EU every year. Following the current global trends emigrants should be perceived as a potential asset. ÉMIGRÉ analyses emigration and diaspora policies of four EU Member States (UK, France, Spain and Poland) as well as EU-level responses to emigration to understand what are the drivers of the emigration governance in Europe and how the policies actually work. Key objectives are: 1) To close the knowledge gap on migration from the EU. 2) To enrich international migration governance studies by providing comparative analysis of actions of EU States in regards to emigration management, over time. 3) To ask what is the relation between State identity formation/shifts and success of policy learning/policy transfer processes between levels of governance. 4) To contribute to evidence-based policy making at the EU level.The project focuses especially on EU emigration to other OECD countries and in particular Canada. It employs a wide range of interdisciplinary methods to collect and analyse data. It also offers an intensive training programme.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'TRends In Global Governance and Europe’s Role' to be submitted under Horizon 2020.

assistant: **Abstract**

The ultimate objectives of TRIGGER are to provide EU institutions with knowledge and tools to enhance their actorness, effectiveness and influence in global governance; and to develop new ways to harness the potential of public engagement and participatory foresight in complex governance decisions, thereby also tackling emerging trends such as nationalism, regionalism and protectionism. These overall objectives are designed to be measurable, realistic and achievable within the 36-month duration of the project. The TRIGGER consortium is composed of 14 partners, including four non-EU countries. TRIGGER will achieve its objectives thanks to the combined effort of four research sub-groups: (i) a group focused on global and EU governance, which will create an unprecedented Atlas of Global Governance REGulation and Europe’s AcTORness (AGGREGATOR); (ii) a group focused on the relationship between governance and emerging technologies; (iii) a group dedicated to strategic foresight and public engagement, which will use new techniques such as AI-enabled sentiment analysis and innovative public engagement methods to develop a tool on Co-Creating the European Union (COCTEAU); and (iv) a group specialised in dissemination and communication. All major deliverables will eventually merged into a toolkit dedicated to Public Engagement for Responsive and Shared EU Strategies (PERSEUS), which will be released at the end of the project.


**Keywords:** public engagement,  foresight,  evaluation,  EU governance,  non-state actors,  transnational private regulation,  emerging technologies
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Neurotransmitter Cys-loop receptors: structure, function and disease'.

assistant: **Objectives**

Cys-loop receptors (CLRs) form a superfamily of structurally related neurotransmitter-gated ion channels, comprising nicotinic acetylcholine, glycine, GABA-A/C and serotonin (5HT3) receptors, crucial to function of the peripheral and central nervous system. CLRs cover a wide spectrum of functions, ranging from muscle contraction to cognitive functions. CLR (mal)function is linked to various disorders, including muscular dystrophies, neurodegenerative diseases, e.g. Alzheimer’s and Parkinson’s, and neuropsychiatric diseases, e.g. schizophrenia, epilepsy and addiction. CLRs are potentially important drug targets for treatment of disease. However, novel drug discovery strategies call for in depth understanding of ligand binding sites, the structure-function relationships of these receptors and insight into their actions in the nervous system. NeuroCypres assembles the expertise of leading European laboratories to provide a technology workflow, which enables to embark on this next step in CLR structure and function. A major target of this project is to obtain high-resolution X-ray and NMR structures for CLRs and their complexes with diverse ligands, agonists/antagonists, channel blockers and modulators, which will reveal basic mechanisms of receptor functioning from ligand binding to gating and open new avenues to rational drug design. In addition, the project aims at understanding receptor function in the context of the brain, focusing on receptor biosensors, receptor-protein interactions and transgenic models. This major challenge requires application and development of a multidisciplinary workflow of high-throughput (HT) crystallization and HT-electrophysiology technologies, X-ray analysis, NMR and computational modeling, fragment-based drug design, innovative quantitati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Belonging for Single Migrant Men: A Cross-Country Comparative Perspective' under Horizon Europe.

assistant: **Concept**

The successful integration of migrant populations requires that individuals who permanently relocate to a host country develop a sense of belonging. This involves not only economic and legal integration, but also the sharing of values, practices, and social networks with others.Single men form the largest group within global migration flows but face the harshest challenges to successful integration and belonging. They are frequently viewed as taking away opportunities from citizens and are deprioritized in social services in favour of families and women. They are also often stereotyped as hypersexualized or criminal.In the face of these obstacles, single migrant men create a range of unique belonging strategies that take place outside family networks and formal integration processes. Yet existing migration research tends to focus on the experience of women and families and the integration of specific groups of migrant men (usually Muslim) in Western democracies. As a result, we know very little about how single migrant men develop a sense of belonging outside of these restricted contexts.In this project, I investigate single migrant men’s experiences of belonging across five countries that have experienced abrupt, large-scale migration flows and that have different gender equality levels and integration policies. These groups include Syrians in Türkiye, Mexicans in Canada, Turks in Germany, Myanmarese in Thailand, and Venezuelans in Chile.My team includes country experts from the disciplines of migration studies, anthropology, sociology, gender studies, and community mental health with expertise in archival research, experimental surveys, interviews and photovoice. I draw on these perspectives to develop a theory of migrant belonging.This comprehensive approach will imp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Customized Surface-Engineered “Nanoglue”: Unlocking Ultrasound-Triggered targeted delivery of CRISPR/Cas complex for Glioblastoma' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Glioblastoma multiforme (GBM), constituting 50.1% of CNS tumors, is the most frequent malignant brain cancer with a median survival of 14.6 months, highlighting the urgent need for more effective treatment strategies. The rise of effective gene therapies especially CRISPR/Cas (“clustered regularly interspaced short palindromic repeats/associated protein 9”) based gene editing technology has sparked optimism for treating GBM. Given the ongoing challenges with CRISPR-Cas gene therapy, such as effective delivery across the blood-brain barrier (BBB), off-target effects, and immune responses associated with Cas9, this research proposal (CRISPRGlue) aims to develop ""nanoglues,"" a novel class of engineered nanogels for targeted delivery of CRISPR tools followed by ultrasound triggered release to address GBM treatment challenges at a European level. The gene editing efficacy of the CRISPR/Cas tools delivered by “nanoglues” will be preliminary investigated as a “proof of concept” by knock-down approach with GFP expressed U87MG cell line followed by targeting EGFR genes which are highly overexpressed in GBM sites. The project unites a dynamic researcher, Dr. Soumen Ghosh, with expertise in synthetic organic chemistry and protein science, alongside POLYMAT, an innovative institute focused on biomedical solutions utilizing nanogels for the controlled release of the CRISPR/Cas9 complex. Prof. Marcelo Calderón, the host supervisor, is a globally recognized researcher leading the “Responsive Polymer Therapeutics Group (RPTG),” a top team specializing in drug delivery using nanogels (NGs). The multidisciplinary expertise required for CRISPRGlue will be complemented by the Smart Bio-Interfaces group led by Prof. Gianni Ciofani. CRISPRGlue will advance the researcher’s career in both a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Asset Level Modelling of RISKs In the Face of Climate Induced Extreme Events and ADAPTtation' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

RISKADAPT will provide, in close cooperation with the end-users/other stakeholders, a novel, integrated, modular, interoperable, public and free, customizable user-friendly platform (PRISKADAPT), to support systemic, risk-informed decisions regarding adaptation to CC induced compound events at the asset level, focusing on the structural system. PRISKADAPT will explicitly model dependencies between infrastructures, which, inter alia, will provide a better understanding of the nexus between climate hazards and social vulnerabilities and resilience. Moreover, this project will identify gaps in data and propose ways to overcome them and advance the state of the art of asset level modelling through advanced climate science to predict CC forcing on the structure of interest, structural analyses, customized to the specific structure of interest, that consider all major CC induced load effects in tandem with material deterioration, novel probabilistic environmental life cycle assessment (LCA) and life cycle cost (LCC) of structural adaptation measures and a new model to assess climate risk that will combine technical risk assessment with assessment of social risks. PRISKADAPT will provide values to a set of indicators for each asset of interest, quantifying primary parameters and impacts, in the form of a Model Information System (MIS) that will provide all required information for adaptation decisions. PRISKADAPT will be implemented in the case studies in the pilots that involve specific assets, however, it will permit customization with local values of parameters and data, so it can be applicable throughout Europe for CC adaptation decisions involving assets of similar function, exposed to multiple climate hazards.


**Keywords:** EO services for climate change forcing in ext
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Doctorate Training in Tuberculosis and HIV Infections'.

assistant: **Objectives**

Chronic infectious diseases constitute the main disease burden in developing countries and an increasing health problem in the Central European countries, which recently have joined the European Union. In particular tuberculosis and HIV/AIDS result in more deaths than any other infectious disease, globally. The two causative pathogens, Mycobacterium tuberculosis and Human Immunodeficiency Virus, very often infect the same host, which leads to the accelerated death of the double-infected individual.The precise mechanisms responsible for the frequent liaison between tuberculosis and HIV infections are not known. The THI-DOC project will offer an opportunity of integrated studies of the association between these two major pathogens explored at the level of host cell and of whole organism using a wide variety of experimental approaches and state-of-the-art techniques. The THI-DOC project will provide integrated training in infection biology, cellular pathogenesis, immunology, molecular epidemiology and the development of novel diagnostics and vaccines against tuberculosis and HIV/AIDS. The program encompasses 3-year training of postgraduate students to obtain a doctor degree.The program consists of:i) research projects carried out under individual tutorageii) a course, seminar and workshop program andiii) evaluation committees for assessment of research protocols and results.The implementation of the THI-DOC project will provide necessary training for Early Stage Researchers from Member States and Third States in which tuberculosis and HIV/AIDS constitute a growing danger to the public health. Spread of knowledge and transfer of know-how will contribute to increased European competitiveness. In addition the THI-DOC project will reinforce the training capability of Host Inst
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Chromatin accessibility landscape and transcription changes in recognition memory after visual imprinting in chicks' (CHARM-Vis).

assistant: **Concept**

The molecular mechanisms underlying memory formation in vertebrates are not well understood, despite their paramount importance to neuroscience. CHARM-Vis aims at investigating changes in the chromatin landscape and transcriptional activity in a prototypical model system for memory formation: visual imprinting in domestic chicks.The expected outcome of the project is remarkable. The use of single-cell, next-generation sequencing technologies will allow to study the system of interest at an unprecedented level of resolution, potentially leading to relevant new discoveries. Novel bioinformatics software pipelines will be developed for analyzing the data, and made available as free, open source software. All the data generated in the project will be made public as well, in order to benefit future research.A highly interdisciplinary consortium of world leading institutions will be involved in the project, including experts in chick visual imprinting from Ilia State University, Georgia, bioinformatics specialists from Navarrabiomed, Spain, and biotechnology experts from Karolinska Institute, Sweden. The combined expertise and synergy of the international consortium, along with the long-lasting scientific experience of the applicant, will ensure the successful fulfillment of the proposal.All the involved parties will greatly benefit from participating into the project. The applicant will deepen his expertise in bioinformatics and neuroscience, reinforcing his position as independent researcher. A mutual exchange of knowledge will take place among the involved institutions, whose know-hows are highly complementary. The project will also have beneficial, long-lasting effects after its end. We expect novel scientific questions to spring from the results of the project, stimulati