RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Sustainable Urban Form For Integrated Climate Change Mitigation Solutions' to be submitted under Horizon 2020.

assistant: **Abstract**

Urbanisation is a global trend poised to continue throughout the twenty-first century. Levels of urbanisation and various aspects of urban form (including density, land-use diversity, street connectivity, and access to public transit and jobs) have been demonstrated in many empirical studies and theoretical models to be important determinants of energy use and greenhouse gas emissions from buildings and transport. However, urban dimensions are absent from models projecting global energy and emissions by country and sector. This omission underrepresents the significant connection between urban dynamics and future emission trajectories, and hinders identification of integrated planning strategies for maximum emission reductions. The main objective of SUFFICCS is to develop and demonstrate a framework for integrated modelling of service levels (m2 floorspace, passenger-km), energy demand, and emissions from urban buildings and transport systems. This modelling framework will be developed using data from urban regions of European countries, and designed for integration with a global dynamic material flow analysis model. Emissions from producing new buildings, infrastructure, and transport equipment will be included, enabling a comprehensive assessment of climate change impacts and mitigation potential of future urbanisation. The incorporation of urban dynamics into energy and climate models, and the linking of transport and buildings sectors through joint dependencies on urban form will represent major advancements in modelling capabilities. These advancements will facilitate assessment of urban and national emission trajectories under various scenarios of urban form, with unprecedented integration of buildings and transport sectors. The aims of SUFFICCS resonate with targe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'IO  Software for Exascale Architecture' (IO-SEA).

assistant: **Innovation**

IO-SEA aims to provide a novel data management and storage platform for exascale computing based on hierarchical storage management (HSM) and on-demand provisioning of storage services. The platform will efficiently make use of storage tiers spanning NVMe and NVRAM at the top all the way down to tape-based technologies. System requirements are driven by data intensive use-cases, in a very strict co-design approach. The concept of ephemeral data nodes and data accessors is introduced that allow users to flexibly operate the system, using various well-known data access paradigms, such as POSIX namespaces, S3/Swift Interfaces, MPI-IO and other data formats and protocols. These ephemeral resources eliminate the problem of treating storage resources as static and unchanging system components – which is not a tenable proposition for data intensive exascale environments. The methods and techniques are applicable to exascale class data intensive applications and workflows that need to be deployed in highly heterogeneous computing environments.Critical aspects of intelligent data placement are considered for extreme volumes of data. This ensures that the right resources among the storage tiers are used and accessed by data nodes as close as possible to compute nodes – optimising performance, cost, and energy at extreme scale. Advanced IO instrumentation and monitoring features will be developed to that effect leveraging the latest advancements in AI and machine learning to systematically analyse the telemetry records to make smart decisions on data placement. These ideas coupled with in-storage-computation remove unnecessary data movements within the system.The IO-SEA project (EuroHPC-2019-1 topic b) has connections to the DEEP-SEA (topic d) and RED-SEA (topic c) project. It lev
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'StarCom Optical Inter-Satellite Link.'.

assistant: **Concept**

Mbryonics Ltd. is an independent Deep tech development company, based in Galway, Ireland, specialising in the design and manufacture of Optical terminals for Optical Intersatellite Links (OISLs) and Optical Ground Station (OGS) and adaptive optics systems.Technology leaders in the application of Freeform Optics for OISLs and Photonic Integrated Circuits in condensed packaging to enable PIC chiplet co-integration with electronics (ASICs/FPGAs) known as ‘co-packaged optics’ or ‘in-package optics’ for technology applications including: Intersatellite links, Telecom, Quantum Networks (QKD), Data Relay, Earth Observation and PNT Pointing, Navigation and Timing and Optical Feederlinks.Established in 2014, with almost a decade of experience developing high-tech solutions through integrated skills in the areas of ICT, photonics, optics, optoelectronics, adaptive optics and aerospace engineering, the team is ideally positioned to deliver advanced optical terminals and photonics solutions for a new era of proliferated space with the advent of mega constellations and a new market for space data over the next decade.Mbryonics are uniquely positioned with an innovative solution based on disruptive application of fibre-coupled free space optical communication (FSOC), silicon photonics and novel application of Additive Manufacturing of Freeform Telescopes and innovation in Assembly, Integration and Test (MAIT) which will overcome previous challenges for volume manufacturing of optical terminals.Mbryonics will utilise a Digital Twin to optimise MAIT and build lean processes to facilitate Sustainability objectives for 2030.


**Keywords:** freespace optical comms, freeform optics, quantum networks, quantum encryption, additive manufacturing, Semiconductors, photonic integrated circuits,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Identification of the genetic and/or epigenetic events that lead to mesenchymal transformation in glioblastoma', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Glioblastoma multiforme (GBM) is the most malignant type of brain tumor in adults with a median survival of one year. The hallmarks of GBM are invasion and neo-angiogenesis. Recently, gene expression studies have established that overexpression of a “mesenchymal” gene signature co-segregate with the poor-prognosis group of glioma patients. We have revealed that two transcription factors, Stat3 and C/EBPβ behave as master regulators of the mesenchymal gene signature. Overexpression of these two transcription factors reprograms neural stem cells along the aberrant mesenchymal lineage, whereas gene silencing in glioma cancer initiating cells (CSC) reduce tumor growth and aggressiveness. Recently, the Cancer Genome Atlas Network has provided information on genomic abnormalities that have allowed the expansion of previous glioblastoma classification studies by associating known subtypes with specific genomic alterations. In particular, EGFR amplification and NF1 and PTEN loss have been linked with the mesenchymal tumor subtype. In this proposal, we would like to identify the genetic events that cause the aberrant expression of Stat3 and C/EBPβ and mesenchymal transformation of gliomas. We have hypothesized that this might occurs by (1) gene copy number variation, (2) mutation in the gene promoter, (3) gene mutation of an upstream transcriptional regulator or, alternatively (4) aberrant DNA methylation of the gene promoter. Will analyze Stat3 and C/EBPβ gene promoter as well as the gene status in GBM samples by performing copy number variation studies and promoter sequencing. The status of CpG methylation at the promoter will be evaluated by pyrosequencing. Finally, we will test the effect of EGFR amplification, as well as of NF1 and PTEN deletion. We will mimic gene deletion
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Bond activation and catalysis with low-valent aluminium' (AlCat).

assistant: **Innovation**

This project will develop the principles required to enable bond-modifying redox catalysis based on aluminium by preparing and studying new Al(I) compounds capable of reversible oxidative addition.Catalytic processes are involved in the synthesis of 75 % of all industrially produced chemicals, but most catalysts involved are based on precious metals such as rhodium, palladium or platinum. These metals are expensive and their supply limited and unstable; there is a significant need to develop the chemistry of non-precious metals as alternatives. On toxicity and abundance alone, aluminium is an attractive candidate. Furthermore, recent work, including in our group, has demonstrated that Al(I) compounds can perform a key step in catalytic cycles - the oxidative addition of E-H bonds.In order to realise the significant potential of Al(I) for transition-metal style catalysis we urgently need to:- establish the principles governing oxidative addition and reductive elimination reactivity in aluminium systems.- know how the reactivity of Al(I) compounds can be controlled by varying properties of ligand frameworks.- understand the onward reactivity of oxidative addition products of Al(I) to enable applications in catalysis. In this project we will:- Study mechanisms of oxidative addition and reductive elimination of a range of synthetically relevant bonds at Al(I) centres, establishing the principles governing this fundamental reactivity.- Develop new ligand frameworks to support of Al(I) centres and evaluate the effect of the ligand on oxidative addition/reductive elimination at Al centres.- Investigate methods for Al-mediated functionalisation of organic compounds by exploring the reactivity of E-H oxidative addition products with unsaturated organic compounds.


**Keywords:**
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'GErmanium MId-infrared plasmoNIcs for sensing' (GEMINI) under Seventh Framework.

assistant: **Objectives**

We aim at laying the foundations of a novel paradigm in optical sensing by introducing molecule-specific strong light-matter interaction at mid-infrared wavelengths through the engineering of plasmonic effects in group-IV semiconductors.The key enabling technology is the novel germanium-on-silicon material platform: heavily-doped Ge films display plasma frequencies in the mid-infrared range. This allows for the complete substitution of metals with CMOS-compatible semiconductors in plasmonic infrared sensors, with enormous advantages in terms of fabrication quality and costs. Moreover, the mid-infrared range offers the unique opportunity of molecule specificity to target gases in the atmosphere, analytes in a solution or biomolecules in a diagnostic assay.We will develop sensing substrates containing infrared antennas and waveguides with antenna-enhanced detectors. Antennas and waveguides will be made of heavily-doped Ge to fully exploit plasmonic effects: high field concentration to increase sensitivity, resonant coupling to vibrational lines for chemical specificity, deeper integration to decrease costs. To achieve our goals we will rely on semiconductor growth by chemical vapor deposition, electromagnetic simulations, micro/nanofabrication of devices and advanced infrared spectroscopy.  We aim at studying the fundamental properties of new materials and devices in order to assess their potential for sensing.Impacts of the proposed research go far beyond transforming optical sensing technology. Lab-on-chip disposable biosensors with integrated readout for medical diagnostics would radically cut healthcare costs. The possibility of actively tuning electromagnetic signals by electrical and/or optical control of the plasma frequency in semiconductors holds promises for dra
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Superelastic Porous Structures for Efficient Elastocaloric Cooling' (SUPERCOOL).

assistant: **Innovation**

Cooling, refrigeration and air-conditioning are crucial for our modern society. In the last decade, the global demands for cooling are growing exponentially. The standard refrigeration technology, based on vapour compression, is old, inefficient and environmentally harmful. In the SUPERCOOL project we will exploit the potential of elastocaloric cooling, probably the most promising solid-state refrigeration technology, which utilizes the latent heat associated with the martensitic transformation in superelastic shape-memory alloys. We have already demonstrated a novel concept of utilizing the elastocaloric effect (eCE) by introducing a superelastic porous structure in an elastocaloric regenerative thermodynamic cycle. Our preliminary results, recently published in Nature Energy, show the tremendous potential of such a system. However, two fundamental challenges remain. First, we need to create a geometry of the superelastic porous structure (elastocaloric regenerator) to ensure sufficient fatigue life, a large eCE and rapid heat transfer. Second, we must have a driver mechanism that can effectively utilize the work released during the unloading of the elastocaloric regenerator. To succeed I am proposing a unique approach to design advanced elastocaloric regenerators with complex structures together with a driver mechanism with the force-recovery principle. We will employ a systematic characterization and bottom-up linking of all three crucial aspects of the elastocaloric regenerator, i.e., the thermo-hydraulic properties, the stability and the structural fatigue, together with a new solution for force recovery in effective drivers. Based on these theoretical, numerical and experimental results we will combine both key elements of our novel elastocaloric concept into a pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Science for Everyone - Sustainability and Inclusion' (SCIEVER), addressing dissemination and exploitation.

assistant: **Impact**

Science for Everyone has been perceived as a motto to involve the general public, especially young students, with research activities and scientific knowledge that may answer to concerns related to sustainability, climate neutrality and social inclusion, major world and European challenges. This proposal intends to directly respond to Responsible Research and Innovation (RRI) goals of the EU framework program by raising the public awareness, also among school communities, about the relevance of science to assure resources preservation, decarbonization and inclusion and by bridging the gap between scientists and society, giving researchers the opportunity to perceive the main concerns of citizens and how those see and understand their work. Schools and their students will be involved in activities during the whole project, in order to ensure the impact in such communities. Thus, by increasing public and students outreach, SCIEVER will contribute simultaneously for two main objectives: (i) improving the understanding of the importance of scientific careers development and science investments; (ii) increasing researchers' understanding of the role of society as a whole for sustainable science policies development. The consortium of this project is coordinated by the University of Lisbon through the National Museum of Natural History and Science and combines efforts between researchers of major universities in Portugal, including four urban areas from north to south  the University of Minho, the International Iberian Nanotechnology Laboratory, the University of vora, the University of Coimbra and the Lisbon University Institute for the impact assessment. Nova University in Lisbon will coordinate a special program targeting school communities and the Superior School for Tour
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Microbial ecosystems biology in the human gut' in the context of a Horizon Europe call.

assistant: **Objectives**

The gut microbiota has wide-ranging effects on host health and represents a promising target for therapeutic manipulation, particularly in early life. Imbalances in the gut microbiota precede the dThe gut microbiota has wide-ranging effects on host health and represents a promising target for therapeutic manipulation, particularly in early life. Imbalances in the gut microbiota precede the development of conditions such as overweight and immunological diseases, which exert a significant burden on society and on individuals. Early identification and treatment of gut microbiota imbalance in childhood thus offers great potential in combatting these problems, and will become an important part of health care in the future. However, achieving this goal will require a high-level understanding of the processes that regulate the microbial populations. Currently our knowledge of the principles governing gut microbiota responses to treatments is insufficient for reliable and targeted microbiota modification. I hypothesize that conceptual limitations are a significant reason for the current inability to reliably predict microbiota responses to treatments and to modify the microbiota. In this interdisciplinary project, based on daily multiomic time series of child gut microbiota and diet and health diaries, I integrate the theoretical and analytical framework of population ecology, novel next-generation metagenomics-based high-resolution quantitative microbiota profiling, and genome-scale metabolic reconstructions into an ecosystem model of the child gut microbiota. The result will be an unprecedented level of understanding of how the gut microbes interact and respond to external forces. The concept can be applied widely to study the numeric and functional microbiota responses to an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'A RADIO NETWORK TECHNOLOGY FOR SHORT RANGE MARITIME COMMUNICATIONS. VALIDATION, ASSIMILATION AND TECHNOLOGY DIFFUSION ACTIONS.' under Fourth Framework.

assistant: **Concept**

The ARCHIPELAGO project is focusing on the pilot implementation, validation and demonstration of a wireless telecommunication network to provide narrowband - Internet compatible - data and voice services, at rates of 2.4-19.2 Kbps, to vessel traffic management authorities as well as ships or smaller vessels crossing environmentally and/or commercially sensitive areas. The core of the implementation will be an existing radio system (originally built for shored based telemetry and data applications) designed on innovative ESMR (Enhanced Specialised Mobile Radio) system principles. This system will be scaled up and adapted. A series of actions is planned to address standardisation issues, define IPR strategy for the SMEs involved in the project, and diffuse the technology throughout Europe. An ArchiPELAGO network is intending to support some of the following application scenarios: - Automatic ship identification and reporting - Updating of electronic charts used by on board Electronic display systems (ECDIS) - Transmission of coded messages (based on standard IMO vocabulary and messages) - Fishing fleet surveillance/Surveillance of environmentally sensitive sea areas - Ship to ship data communications - Coast guard short message, data/e-mail and voice, (ship to ship and ship to shore) - E-mail over Internet and WWW browsing - Fleet management (for instance: fishing fleet surveillance) - Access of port/ship operator's Intranets - Access, via Internet/Intranet or directly, of databases and Travel Information. In the next few years European Union Countries such as Spain, Portugal, France, Italy and Greece will invest millions of ECUs in vessel traffic management (VTS) infrastructures. This is due to the fact that today's VTS make extensive use of very expensive radar sensors,