RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'The role of chromosome stability in persistence, latency and reactivation of mycobacterium tuberculosis'.

assistant: **Innovation**

Tuberculosis causes more deaths than almost any other infectious agent, with nearly 2 million deaths each year. One-third of the world's population is latently infected with the causative agent, Mycobacterium tuberculosis. The ability of M. tuberculosis to enter into a latent state is thought to be the reason for the prolonged period of treatment required to prevent relapse, since drugs currently available mainly target actively growing bacteria.The vast pool of latently infected individuals is a constant source of disease and transmission, as factors weakening the immune response, such as HIV infection, lead to the emergence of active disease and infection with TB is a significant cause of AIDS-associated mortality in developing countries. This project suggests to tackle the problem of latency by focusing on the mechanisms that govern chromosome integrity. There is evidence that M. tuberculosis is exposed to DNA-damaging conditions in the host during latent infection.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Architectural Environments for Smart Organisation Portals'.

assistant: **Concept**

AESOP aims to develop a coherent architectural approach to change management and to the configuration of services and systems to support and faciltiate the transformation of public agencies into Smart Organisations. This will support a flexible approach to the allocation of shared and dedicated resources and provide the means for horizontal and vertical integration of value chains through brokerage and intermediation mechanisms with three pilots in Regional Chambers of Commerce.Work description:Phase 1 is concerned with establishing pilot baselines and in selecting and assembling the initial technical platform.In the second phase, the three Chambers contexts will pursue different aspects of the brokerage environment.These will include:- Information management, catalogues, profiles and content;- Transactions and case management which is distributed in time and across organisational boundaries;- Service management and the relationship between operational information and vertical reporting.In each case, a cycle of refining the baseline, organisational modelling and requirements exploration will mesh with a process of populating and evaluating an evolving delivery system.Generic models and demonstrations of the brokerage environment will also be produced and examined on an Europe wide context through validation workshops organised by an agency which represents Chambers across Europe.In the third phase, the three strands will be integrated into more complete implementation at each of the three user sites and demonstrations to a wider audience will be undertaken through the Eurochambers agency.Milestones:M1 - establishing pilot baselines and selecting and assembling technical platform for the Third generation Web portal;M2 - Integration of technical platform in Chamber pilots
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Projecting the fate of Arctic and Alpine ungulates: how past climate and harvesting shaped genetics and demography' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Conserving biodiversity urgently requires the integration of knowledge across ecological-time, -scales and -disciplines. AA-ungulates will fulfil such major ambition, developing an innovative framework joining palaeoecology to evolutionary demography. By extracting invaluable knowledge from millennia of natural history and detailed demographic data, this project will provide advances in predicting species persistence under rapid global changes. Specifically, the project will study 1) the effect of climate and harvest on effective population sizes of Arctic and Alpine ungulates at historical (using subfossil genomics) and 2) contemporary (using genomics and demography) timescales, to 3) project their population viability under credible climate scenarios.To achieve these novel goals, I propose a pioneering approach linking state-of-the-art genomics from ancient and modern specimens to individual-monitoring programs. To maximize societal impacts, the research focuses on charismatic ungulates sharing histories of hunting-induced bottlenecks and inhabiting biomes warming the fastest on Earth. These unique empirical datasets will allow theoretical advancements by identifying common genetic-to-demography processes, with important insights on how population viability is tied to low genetic diversity.To undertake this integrative endeavor, a two-way transfer of knowledge will be crucial between the Beneficiary (Université Savoie-Mont Blanc, USMB, France) and I. In G. Yannic’s expert group, I will learn about alpine ecology and paleogenomics and in turn will bring knowledge of arctic ecology and demographic biostatistics. A strong collaborative team from 9 institutions in 4 countries, gathering eminent specialists in key aspects of AA-ungulates, will further enrich my network and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Technologies for Active Vibration and Acoustic Comfort' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

In aircraft cabin environments, vibrations and noise co-exist affecting the passenger comfort, quality of flight, but also aircraft efficiency. To progress on airframe and engine efficiency while supporting the high level of customer comfort requested, the faced challenges are to develop and integrate into the airframe and cabin new technologies of active noise and vibration reduction, without penalizing the weight, fuel efficiency and performance of the aircraft. The main aim of the proposed research is the development of novel integrated active technologies for noise and vibration reduction and their integration into aircraft fuselage and cabin. This is accommodated in two discrete, but highly related directions: (1) Active vibration isolation and control of engines and aerodynamically induced loads; (2) Active noise control. Each of the approaches is subjected to its own specific performance and weight limitations.The project focuses on the application of light-weight, power efficient and compact in size 3D printed electro active loudspeaker arrays for noise control, and on induced-strain piezoceramic actuators for vibration control. Advanced and light-weight controller and amplifier electronic modules will be developed by the industrial partner MILTEC. Virtual testing and optimal system design methods are proposed for the detection of the appropriate actuator characteristics, locations for the more efficient placement, required power and optimized controllers, in connection to the specific application details attention will be focused. Miltech as the industrial partner, will use the experience from previous project related with aircraft integrated systems. These should balance between the potentially optimum provided performance with the compact size and weight.  TA
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Dissecting gamma-TuRC composition and activity by Single Molecule Pull-down'.

assistant: **Innovation**

In this project I will use Single Molecule Pull-down (SiMPull) for studying activity and regulation of human gamma-tubulinring complexes (gamma-TuRCs). Gamma-TuRCs are the main nucleators of microtubule (MT) polymerization. Additionally, gamma-TuRCs may play a role in modulating MT dynamics. Regulation of gamma-TuRC activity is key to organizing the dynamic MT arrays needed for essential processes in various cell types. Progress in understanding gamma-TuRC regulation at the molecular level is currently hampered by a lack of information about subunit stoichiometries and interactions, and by technical difficulties that have prevented reconstitution of gamma-TuRCs in vitro. I will tackle these challenges by using SiMPull to immunoprecipitate and immobilize gamma-TuRCs to a glass surface directly from cell extracts collected at different cell cycle stages, and analyze individual gamma-TuRCs using high resolution microscopy. I will express tagged gamma-TuRC subunits in cells to isolate wildtype and mutant gamma-TuRCs. Using fluorescent protein tags and antibodies I will visualize and quantify components in individual gamma-TuRCs and, by incubation in pure tubulin and GTP, determine how gamma-TuRC composition is related to its ability to nucleate MTs and modulate MT dynamics. Together, the proposed research will expand the field’s toolbox, thereby allowing new, molecular level insight into gamma-TuRC activity and its regulation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Ethnicity, Gender and Education: The School Experiences of 14-year-olds in a London Comprehensive'.

assistant: **Objectives**

Research objectives and contentThe empirical research project to be carried out will consist on the case study of an inner-London comprehensive school. By focusing on the school experiences of 14 years old pupils, this ethnographic study will explore the impact of ethnicity and gender on educational opportunity, paying, particular attention to the school experiences of pupils of African origin, which have been to some extent neglected in the academic research on black pupils.More specifically, this research project has the following aims:1. To know if teachers differentiate significantly between pupils of African and Caribbean origin and, if so, what are the different stereotypes that they construct out both groups and how do these affect their educational expectations.2. To explore teachers' perceptions and educational expectations of pupils of different gender of each ethnic group3. To explore pupils' ethnic and gender identity.4. To understand how pupils integrate and reproduce 3 stereotypes on /ethnicity and gender in their everyday school experiences with their peers and through interaction with their teachers.Training content (objective, benefit and expected impact)The research project to be carried out is part of the Doctoral studies in education that I will undertake in the Policy Studies Academic Group of the Institute of Education, University of London. Therefore, I will attend a Programme of research training. The research project itself will allow developing my skills as researcher in Social Science I namely, in planning and conducting interviews observations and analysing the data generated with such methods. Also, it will prepare me in analysing written documents (such as educational policies and with school documents)Links with industry / industrial relev
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Revealing Antibiotic Resistance Evolution' in the context of a Seventh Framework call.

assistant: **Objectives**

Antimicrobial resistance is a global public health problem. Bacteria can quickly develop resistance against many of the existing antimicrobials, and consequently prolonged treatment periods lead to human suffering, loss of productivity, and high health care costs. In order to tackle the antibiotic resistance problem, either new antibiotics or methods for using the current collection of antibiotics more efficiently is necessary. Here, I propose an experimental study to uncover the evolution of bacterial drug resistance which I believe will be very valuable for slowing down the spread of resistance by using the currently available antibiotics. The specific aims of this proposal are: (1) Measuring the rates of evolution under single drug and drug combination treatments; (2) Examining pleiotropic effects of (non-drug) stressful conditions on evolution of drug resistance; (3) Measuring the epistatic interactions between mutations that confer antibiotic resistance. We will perform these studies by using high-throughput measurements and a custom made fully automated fluidics system, “the morbidostat”, which can unequivocally follow bacterial evolution in antibiotic environments. Being able to understand the evolution of antibiotic resistance both at the population and enzymatic level, and identifying the pleitropic effects that cause antibiotic resistance will be very helpful for planning interventions to combat antibiotic resistance.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Multi-Stakeholder Partnerships in Post-Conflict Reconstruction: The Role of the European Union' (MULTIPART).

assistant: **Concept**

By consolidating and advancing the knowledge on factors that facilitate peace and foster human security, this project meets the goals of the 7th Framework area 8.4.2. Conflicts, Peace, and Human Rights. Namely, it investigates whether, how, and under what conditions multi-stakeholder partnerships can positively impact on human security and thus, facilitate non-violence and long-term peace, and provide a productive framework for relations between local actors and external actors, including third party mediators and international organisations. The project moves from the recognition that there is a widespread agreement among both academics and policy makers on the need to adopt more comprehensive, integrative, and participatory approaches in post-conflict interventions. Within this broader framework, multi-staekholder partnerships are then emerging as one of the preferred tools geared towards enhancing participation, legitimacy and effectiveness of post-conflict interventions. However, there is a clear lack of systematic analysis of the multi-stakeholder partnerships and of evaluation of their concrete impact on effectiveness and sustainability of post-conflict reconstruction initiatives. The project will base its empirical investigation on three core case studies of core political interest to the EU today: Kosovo, the Democratic Republic of Congo (DRC), and Afghanistan. By employing a participatory methodology, the project will ensure the highest degree of on-going feedback between its researchers and different local and international actors operating in these settings and will explore opportunities to directly impact on partnerships that are evolving in these societies. By translating its findings into policy recommendations, the project will contribute to enhancing the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Property Assessed Clean Energy' (PACE), addressing dissemination and exploitation.

assistant: **Impact**

The aim of this research is to contribute to sustainable development, by proposing a candidate policy for promoting renewable and energy efficiency deployment, mainly in households, and comparing its merits with existing alternatives. Accelerating clean energy adoption will not only contribute to sustainable development, by reducing Greenhouse Gas (GHG) emissions, but also to addressing energy poverty, by helping households to improve the energy efficiency of their homes and reduce their heating and electricity costs.The idea is to catalyse private capital to cover upfront energy investment costs and then recoup payments through increased property taxes. In particular this project will help:1.establish environmental policy priorities based on sound research and policy analysis,2.diagnose key market constraints to delivering energy efficiency improvements and renewable adoption, and3.propose structural economic reform priorities to overcome these barriers.There are several reasons to carry out further analysis in this field:- this will help gain a better understanding of the risks and barriers associated with clean energy financial structures as well as building regulatory frameworks which encourage clean technologies adaption;- the need to make available new financing tools that take different country-specific contexts into account;- the need to develop economic models, that help analyze these issues leading to better policy recommendation.This project aims to suggest varying design features for the proposed financing tool adapted to different country-specific contexts across a range of OECD countries as well as providing policy recommendations, for different countries.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Development of an environmentally friendly and cost-effective modular hydraulic rock-splitter system forefficiently breaking large rocks for an improved use in stone quarry extraction' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

In 2007 EU countries represented about 40% of global natural stone production, bringing Europe as one of world’s largest produces and exporters of natural stone. European countries like Italy, Greece, Portugal, Sweden, and Spain, are important players while other European countries are in positively growing. The European sector consisted of 60,000 companies and employing a total of more than 500,000 workers is strongly dominated by SMEs, being more than 90% and having less than 50 employees each. In spite of its leading role on the global market, Europe has been loosing power due to non-European aggressive trading competition bringing a decrease in employment of more than 15% in the last 6 years. At extraction only 20-25% of extracted rocks are accepted, meeting the requirements for being further processed into a cost-efficient product. This quantity constitutes a major environmental impact because the discarded rocks (75-80%) are considered unprofitable to process into valuable products.Within this framework, the need for a reliable and cost-efficient extractive tool is of great importance for the competitiveness of the European quarrying industry. This project is based on two patents and will involve the development of a novel cost-efficient and environmentally friendly system which exploits pressurized water to efficiently split large rocks during quarry extraction activities. The system will be designed to bring several advantages with respect to explosives and other extraction technologies, to potentially replace them thanks to its higher productivity and extracted rock quality. The system will be suitable for different rock types and could be used in different environmental and vibration sensitive areas without damaging the surrounding rock or causing excessive di
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'ADAptive circuit techniques for current-mode ultra low-power diGItal Integrated Circuits' to be submitted under Seventh Framework.

assistant: **Abstract**

In the last years, the demand for ultra-low power integrated circuits with sub-1mW power consumption has been rapidly growing, due to the diffusion of applications relying on a large number of circuit nodes that are powered with tiny batteries or extract their energy from the environment (e.g., wireless sensor networks). These circuits must also be provided with sufficient computing capability for signal processing purposes, hence the design of ultra-low power digital circuits is a key aspect in this area. In this project, innovative circuit techniques to design ultra-low power digital circuits are developed. The MOS Current-Mode Logic (MCML) logic style is adopted in place of the standard sub-threshold CMOS logic, as MCML circuits were recently shown to be very well suited for ultra-low power operation thanks to the good control of their bias current. In addition, the prospective research activity targets the development of an efficient tuning scheme that adaptively varies the MCML gate bias current to compensate the inevitably large delay variations, adapt the power consumption to the available energy and the required performance, as well as to suppress the power contribution of inactive blocks. Accordingly, criteria and methods to design MCML standard cell libraries and use them in standard CAD design flows will be developed. To further reduce the consumption, an ultra-low voltage technique to halve the minimum supply voltage of MCML circuits will be introduced. Compared to sub-threshold standard CMOS logic, the joint adoption of the MCML logic style and the adaptive scheme is expected to significantly reduce the power consumption and to strongly enhance the circuit robustness against variations. Besides, the ability to tune the power consumption and the performance