RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'A European strategy for the integration of research on breast cancer' (EUSTIR).

assistant: **Innovation**

The overall objective is to create a permanent European overview process for the award, audit and recording of all research on breast cancer: This will be the creation of the funding bodies themselves which, for each project, will retain the absolute power of award. The present methods of awarding research grants in cancer suffer from many defects & results in repetitive research, often of no clinical relevance. There is no agreement as to which areas are the most important, there is no attempt to ensur e that claims are validated, there is no audit process for success/failure & no ranking of ability to individual units to complete projects & their value. This means that monies for research are spent poorly. These problems will be addressed in bre ast cancer in this project, which aims to create: 1.A European overview process for project proposals received by all funding bodies. This will i) prevent research from being funded for similar work in multiple projects ii) result in a few large, rather th an multiple small series, which are are much more likely to yield definite results. 2.A body of the leading researchers in breast cancer which agree the areas most likely to give results of clinical relevance and agree certain issues that must be included in all proposals (such as validationof the results). 3.An audit process of research work. This addresses the problem that many projects do not address their aims. The audit outcomes will be accessible to research funders, so that institutes most likely to complete valuable projects are identified (and the converse!).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Chatgrape. The world’s most advanced team chat meets enterprise search.' under Horizon 2020.

assistant: **Concept**

Up to 25% of employee work time is wasted on communication and searching data, implying billions of euros in all market segments. Especially in the case of highly paid professionals and managers, capturing this lost productivity will raise profits and margins across all industrial sectors. The unified business communications market is a huge market (€15 Billion in 2015) with big players from the US leading this segment. The only way to obtain a significant share in this market is to radically change the format of enterprise communications by offering a set of unique features that our competition cannot bring.Grape is our solution to facilitate new ways of enterprise communication and file-indexing by working solely from the chat. We have developed smart technology to accelerate the browsing process, and integrated browsing options within the chat to access internal and external data. Being a European alternative and being the only solution without servers in the US, we offer enhanced data privacy and security.To bring Grape to the next level, we will need to put an end to “slash-commands and bots”, which work great for insiders but have less adoption with casual, normal users “outside our little tech industry bubble”. Therefore, we aim to include natural language into our chats that will allow easy-to-use and more efficient communication. It will also give another competitive edge to Grape.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'An Evolutionary Approach to Biodiversity Conservation: Riverine Floodplains of the European Alps as a Model System'.

assistant: **Innovation**

The importance of evolutionary relatedness of species is increasingly recognized in both ecology and conservation. What remains is a need for quantitative predictions on the role of evolution and a synthesis of methods. This project uses DNA surveys of aquatic insect communities to measure species diversity and genetic relatedness in riverine floodplains. Riverine floodplains are one of the most biodiverse ecosystems on earth and create a very high spatio-temporal heterogeneity. Unfortunately, the most diverse and abundant aquatic insects are poorly known at the species level, therefore research that has been carried out to link biodiversity and the spatio-temporal heterogeneity relies on estimates of diversity and has lacked an evolutionary perspective. The project examines the role of habitat heterogeneity in the evolutionary processes of structuring biodiversity by sampling communities from 4 habitat types at each of 6 study reaches along 3 natural riverine corridors in the Alps. It will construct a ‘DNA profile’ of macroinvertebrate communities using DNA sequences and coalescent-based modeling to delineate species, determine the extent of local and regional endemism of species, reconstruct a phylogeny of all samples and calculate phylogenetic diversity of individual habitats, individual reaches, and whole river corridors, and use the resulting tree topology to examine the degree of phylogenetic clustering and overdispersion as a means to quantify the role of evolution in community assembly. The project explores 3 timely research topics: the linkage of ecology and phylogeny, the integration of evolutionary criteria in conservation management, and DNA-based biodiversity surveys. The applicant has high potential for knowledge transfer to the European freshwater science
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Fostering the transitiOn foR sustainablE and circular bio-fuelS: an Eco-labEl and moNitoring tool as a guidance for policies' under Horizon Europe.

assistant: **Concept**

The objective of FORESEEN (Fostering the transitiOn foR sustainablE and circular bio-fuelS: an Eco-labEl and moNitoring tool as a guidance for policies) is to design, implement and validate a digitalised toolkit and an eco-label aimed at improving and ensuring compliance with decarbonization strategies, policies, and regulations and promoting sustainable and circular biofuel technologies and value chains. The toolkit's architecture will be developed with consideration of the Safe and Sustainable by Design (SSbD) and circularity frameworks and integrating data science for enhanced data analysis and predictive modelling. The eco-label will certify biofuel technologies and value chains that meet sustainability, circularity, and safety standards. The integration of policies, circular bioeconomy indicators, SSbD framework, and digitalization within the FORESEEN project toolkit and eco-label will drive the adoption of advanced sustainable biofuel technologies and value chains.


**Keywords:** Safe and Sustainable by Design,  Circularity,  Biofuels,  Eco-label,  Digitalized tool
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Monitoring biodiversity of pico-phytoplankton in marine waters'.

assistant: **Objectives**

Problems to be solved.Picoplankton (defined operationally as cells that pass through a 3 micron filter) dominate the photosynthetic biomass in many marine ecosystems, not only in the very oligotrophic regions of the world oceans, such as the Eastern Mediterranean Sea, but also in mesotrophic areas. However, picophytoplankton are clearly not exclusively restricted to pelagic environments. In many coastal regions, they are present throughout the year and constitute a 'background' population, onto which episodic phenomena such as the spring bloom develops. In some environments, such as coastal lagoons, picoplankton can be a major component of biomass and productivity for most of the year. In addition, some bloom-forming picoplankters such as Aureococcus spp. are toxic. However, to date fewer than 30 species of picophytoplankton have been described. A clear proof of our poor knowledge of picophytoplankton diversity is revealed by the discovery of three novel algal classes in the last ten years described from picophytoplanktonic taxa. Because so little is known about the taxonomy and systematics of picophytoplankton we have very little data to estimate the levels of its biodiversity under natural conditions and how picophytoplankton are affected by environmental variability linked to either anthropogenic influence or to larger scale phenomena such as those linked to climate change or global warming.Scientific objectives and approach.The major objective of this project is to develop, test and validate probing methods based on molecular biology techniques that allow for routine and extensive assessment of picophytoplankton diversity (species composition and relative contribution of taxa to total community) in the marine environment.Our strategy to meet this objective is encaps
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Utility and Unique Chemistry of Homoallylic Amines with a Difluoromethyl- and Fluoro- Substituted Stereogenic Carbon' (TRIFLUORO-BUNDLE) targeting Horizon Europe.

assistant: **Abstract**

Organofluorine compounds are scarce in natural products, but they are central to therapeutic science, agrochemical development and materials research. Incorporation of fluorine atoms within an organic molecule can have profound effects on pharmacokinetic and pharmacodynamic properties. Enantiomerically enriched fluoro amino acids possess physiochemical and biological properties that distinguish them from canonical amino acids and are key to advances in biological sciences, including peptide and protein engineering. On another front, many azasugars that have high pharmacological potential suffer from weak binding affinities and inferior pharmacokinetic properties; this problem may be addressed through glycomimetics. A promising strategy in glycomimetics entails H-to-F and OH-to-CF2H exchange. A compelling objective in modern chemistry, therefore, is the development of efficient, and practical strategies for diastereo- and enantioselective synthesis of readily modifiable organofluorine fragments that have a CF2H moiety. However, while enantioselective methods that can be used to form a C(sp3)CF2H stereocenter are available, none apply to the formation of products bearing a fully substituted carbon stereogenic center that has a CF2H and a F substituent. To address this problem, we will develop a robust, practical, and scalable catalytic strategy for practical, efficient, diastereo- and enantioselective conversion of nitriles to homoallylic amines with a CF2H- and F-substituted allylic carbon. Our investigations will focus on an important but severely underdeveloped class of transformations, namely, catalytic diastereo- and enanantioselective addition of a carbon-based nucleophile to nitriles. We plan to utilize the new catalytic approach as the key design element in highly
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Transforming and Defending Multilateralism: European Union Support for more Robust, Effective and Democratic Global Governance' (ENSURED) under Horizon Europe.

assistant: **Objectives**

The European Union (EU) and its members have long been key supporters of global governance. Yet the rules-based international order and multilateralism are widely believed to be in crisis. The emerging powers and populist forces have contested and put demands on global governance often resulting in a gridlock of international cooperation. The Russian war in Ukraine will likely further undermine the ability to address global problems. ENSURED, a project with 14 partners from the EU, US and the BRICS, studies how the EU and its members, in a contested world in transition, can transform and defend global governance to make it more robust, effective and democratic. Integrating different literatures on international institutions and EU foreign policy, ENSURED develops a conceptual framework on global governance transformation. It outlines a triangular dilemma in which the EU and its members must make choices between the robustness, effectiveness and democracy of global governance. It also considers, in this respect, different scenarios for multilateralism in a contested world in transition. Through case studies of five policy areas, a quantitative analysis and expert survey, ENSURED empirically assesses and compares the unexploited potential for global governance transformation. It thus highlights areas where global governance transformation is most likely. Based on this empirical analysis, ENSURED provides support for the EU and its members to lead the transformation and defence of multilateralism. It outlines strategic choices and develops decision support and communication products that the EU and its members can use, such as an online toolkit, policy recommendations and strategic narratives. ENSURED thus advances our knowledge about global governance transformation and p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on '8th international conference on the chemistry and migration behaviour of actinides and fission products in the geophere'.

assistant: **Innovation**

The MIGRATION conference is known as the most important international conference in the chemistry of actinides and fission products in the geosphere with emphasis on the disposal of nuclear waste in geologic formations. The number of participants has increased from 240 in 1987 to 360 in 1999. The conference takes place alternately in Europe, USA and Asia since 1987. The conference papers are peer-reviewed and published in special issues of the internationally reknown journals Radiochimica Acta and Journal of Contaminant Hydrology. Therefore, the MIGRATION conference is accepted as an international platform for the exchange of research progresses in the field of radionuclide geochemistry. MIGRATION' 01 will take place in Bregenz, Austria, in September 16-21, 2001. Within the present proposal the organizers ask for financial support to prepare the conference proceedings.The MIGRATION conferences provide an international forum for the timely exchange of scientific information on chemical processes controlling the migration behaviour of actinides and fission products in natural aquifer systems. Experiment and predictive modelling of these processes are the main topics of the conferences. The information generated from the MIGRATION conferences has led to abetter understanding of the migration behaviour of long-lived radionuclides in the geosphere, which is essential for the long-term performance assessment of nuclear waste disposal.Until end of February, abstracts are collected and reviewed by the international steering committee in march 2001. Until April 15, 2001 the authors are notified and informed about presentation guidelines, and other organisational details. July16, 2001 the final programme will be distributed, papers will be collected until August 2001 and the conf
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Regulation of lymphocyte biology by ubiquitin and ubiquitin like modifiers' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

T lymphocytes are key cells of the adaptive immune system that protect us against pathogens and malignant cells. T cell activation and differentiation are tightly controlled processes and deregulation can result in lymphomas, autoimmunity and inflammation. Hence, the biochemical events regulating lymphocyte biology have long been a topic of intense research, which has been focussed predominantly on protein phosphorylation. I hypothesize that there are crucial roles undiscovered in T cells for other posttranslational modifications (PTMs) such as ubiquitin (Ub) and Ub-like proteins (UBLs). The importance of ubiquitylation in adaptive immunity is implied by the severe immunological disorders observed when components of the Ub system are disrupted in lymphocytes. Genetic approaches in mice give a limited understanding about the roles of these modifiers and do not reveal the full extent to which Ub and UBLs regulate lymphocyte biology. Deterred by the complexity of the Ub system, the field has not yet tackled the daunting challenge of systematically investigating these modifiers in vivo. The goal of this proposal is to define how T cell function and immune responses are regulated by Ub and UBL signalling networks. To pioneer substantial progress in this area, we will develop new methods to identify and characterize currently unknown recognition modules for the different modifications. We will elucidate the Ub and UBL modified proteome in lymphocytes and characterize dynamic changes of these PTMs during T cell activation. By focussing on enzymes that remove the modifications we will discover how these PTMs are regulated and define Ub and UBL-dependent signalling nodes. Each phase of the work will deliver fundamentally novel mechanistic insights into these PTMs while rewriting
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for '“Restorative Justice in Magdalene Cultural Production from Western Europe, North America, and Oceania (1836-2023)”' in the context of a Horizon Europe call.

assistant: **Objectives**

The project assesses the intertwinement between Magdalene cultural production and restorative justice in transnational contexts. By analysing a corpus produced in three distinct geographical, historical, linguistic, and cultural areas, the research interrogates the cultural specificities of Magdalenism across space and time, beyond the frame of Irish studies. The project explores the spectrum in which genres convey and publicise traumatic experiences, from empowering survivors, to sometimes financially exploiting their tragic narratives. Culturally sensitive trauma-reading methodologies will be used to read texts from Ireland, the United Kingdom, Canada, the United States, Australia, and Aotearoa New Zealand. The process of restorative justice will also be analysed with regards to the decolonisation of Magdalene trauma studies, as Indigenous womens experiences will be examined with care, and not retraumatise nor recolonise their communities. Narratives testifying to systemic racism, sexism, classism, ableism, and homophobia will be excavated to question the treatment Magdalene women and their children endured in modern nations and in settler colonies. Ireland, Northern Ireland, Australia, Canada, and Aotearoa have set up Truth and Reconciliation Commissions covering the issue of Magdalenism in addition to wider institutional histories. Magdalene fiction and non-fiction contribute to restoring survivors credibility in patriarchal structures, by contesting official and hegemonic writings of history which erased or minimised them from national narratives. They are also valuable documents in the way they highlight how the Magdalenist heritage continues to fashion femininity, single motherhood, and female sexuality in the twenty-first century, as Magdalene cultural productio