RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Injection molding of hollow components'.

assistant: **Innovation**

According to the project programme, the major deliverables have been achieved as planned. No significant deviations between planned and actual work have been encountered. Task 1 and 2 (in particular the sub-task 1.1, 1.3, 2.1 and 2.2) have been completed as planned; sub-task 1.2 has been extended to the month 21 to allow a more robust design of project final demonstrators, requiring reliable materials properties. Task 3, 4 and 5 are still in progress as planned. Main partners involved in Task 3 (ENSCI, POLI TO, CERECO and IFAM) have investigated the perfect combination between powders, binders and low fusible alloys to apply the lost core technique to PIM parts. In particular, the technical work focused on i) the definition of an organic binder system suitable both for metallic and ceramic powders and ii) the definition of the right low fusible alloy in order to perform injection molding, debinding and sintering without distorting, polluting or damaging the components.In particular, the development of reliable powder injection molding technologies for hollow components has been carried out by the integration of the different competencies, from materials sciences to mechanical engineering through process simulation and modelling. The research efforts have been devoted to the proper selection of materials and related processes and to the development & optimisation of the overall process through modelling and representative mock-ups manufacturing.Concerning the materials analysis and selection (Task 3), CRF, POLI TO, CERECO and ENSCI co-operated with the purpose to tune all processing steps regarding silicon nitride, MMCs and CMCs materials. Debinding and sintering tests of different silicon nitride and sintering aids compositions have been carried out, leading to good res
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Effect of Hypoxia on fish locomotion, foraging and escape performance' under Fifth Framework.

assistant: **Concept**

The project will investigate the effect of hypoxia on biological processes involved in fundamental phases of the prey-predator relationships. Investigations will be conducted in two commercially relevant fish species: European sea bass and grey mullet which inhabit Mediterranean lagoons where hypoxic episodes occur regularly. Escape. Feeding and locomotor performance at various levels of oxygenation (100. 50. 20% oxygen saturation) will be studied. Data obtained in the two species will be compared to provide information oil the species-specific features of hypoxia tolerance.Escape performance is will be assessed by. measuring a set of characteristics of the locomotion performance and the sensivity to startling stimuli. The effect of hypoxia on feeding will be estimated in grey mullet (detritivore) foraging on a benthic substrate and in sea bass (predator) feeding on grey mullet juveniles. Predator error rate.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Utilizing an innovative chemical platform to defeat antimicrobial resistance' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

We tackle the challenges posed by the emergence of antimicrobial resistance (AMR) with a conceptually new approach. We have established a scalable chemical platform for the development of novel antibiotic resistance breakers (ARBs). Our compounds sensitize the pathogen and restore the effectiveness of standard-of-care antibiotics. By circumventing the painstaking process of discovering and developing new antibiotics, we bring forth a more cost-effective approach to confront the emergence of AMR. Allowing pharmaceutical companies to protect decades worth of R&D efforts and billions of euros in development costs, we present them with an attractive value proposition. Our platform enables the fast, high-yield production of ARBs against gram-positive bacteria (GmPcides). Our compounds have displayed effectiveness against two of the most threatening drug-resistant pathogens MRSA and VRE. Moreover, the compounds exhibit a strong in vivo synergy with two of the world’s most essential antibiotics Gentamicin and Vancomycin.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Applying Hypothesised Cause-and-Effect Relationships (HCER) for Evaluating Investments in Manufacturing Process Technologies (IMPT) and Measuring their ex-post Performance'.

assistant: **Innovation**

Research objectives and contentThe project's research objective is the development and testing of an original, state-of-the-art method for evaluating investments in manufacturing process technologies (IMPT) and measuring their actual performance. The need for such a method has been suggested very recently by a number of empirical surveys and case studies of medium-sized European companies. In particular the project will focus on investments in the improvement of manufacturing capabilities. This has far reaching effects for the competitiveness of European manufacturing industry. The project builds upon the latest research findings in Operations Management and joined findings in Management Accounting and Strategy. A method will be developed, that integrates hypothesised cause-and-effect relationships, a basic principle of the Balanced Scorecard, and the dichotomy of order-winners/qualifiers. The latter was developed by Prof. T.J. Hill from London Business School and the previous by R. S. Kaplan from Harvard Business School. The method will then be tested for its applicability for evaluating investments in manufacturing process technologies and the measurement of their ex post performance. This will be done in two series of case studies. The findings will be compared to anticipated research findings from the US and the Far East and valuable recommendations for the European manufacturing industry derived.Training content (objective, benefit and expected impact)The training objective of the proposal is to deepen the applicant's knowledge and to widen his competence in the field of Operations Management. It will provide him with a clear, insightful and broader European dimension of his work and allow him to complete a crucial step in his academic curriculum by acquiring a doc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Inline/Instant Measurement for PhArma eXtrusion' (IMPAX), addressing dissemination and exploitation.

assistant: **Impact**

Most pharma companies still rely on the age old batch manufacturing method and today the European Pharma industry faces the major challenge of strong competition from lower cost manufacturers. The trend is disinvestment in Europe or alternatively investment in innovative manufacturing technologies and more advanced and targeted pharmacological products.Batch manufacturing implies inflexibility, high costs and poor biological delivery of more advanced new drugs. New techniques like Continuous Manufacturing, extruder based Hot Melt Extrusion and Wet Granulation are the future, allowing for automation, improved efficiency, and proper bioavailability for poorly soluble molecules. Safety and fulfilment of their potential mean these new processes require much more advanced Process Analytical Technology than is currently available. ColVisTec will extend its unique UV-VIS platform to incorporate NIR and Raman. IMPAX represents the first production monitoring platform to combine three spectra (UV-VIS, NIR and Raman) and will provide extensive, real time, spectroscopy measurements adapted to the extruder environment with pharma software compliant with EMA and FDA regulations.The initial markets will be Europe and the USA, where ColVisTec is already active. IMPAX users like pharma companies, contract manufacturers and universities will benefit from access to lower cost production and an innovative solution for drug delivery. Important pharma stakeholders (AbbVie, Endcap, FCNW, Catalent, BASF and Reutlingen University) have already shown their interest and support in written form and undertaken to test the new IMPAX platform at their facilities. IMPAX will contribute to Europe’s pharma industry adopting “Industry 4.0” digitalisation and automation principles and will facilitate the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Modelling Endogenous Technical Change in Agriculture for Food Security' to be submitted under Seventh Framework.

assistant: **Abstract**

This Marie-Curie Project METCAFOS (Modelling Endogenous Technical Change in Agriculture for Food Security) represents an inter-sectoral mobility that significantly enhances the transfer of knowledge in a training-through-research framework by combining knowledge from various disciplines, namely mathematical optimization, econometrics, production technology, institutional and development economics.The objective of METCAFOS is to endogenise the drivers of technical change in the global CGE model MAGNET with the aim of improving the quality of food security projections towards 2050 and contributing thus to the understanding of the role of the technical change in reaching food security for the world population.The implementation of METCAFOS will be carried out in four stages, consisting of the compilation of global database for the empirical estimates of the drivers of technical change, the estimation of endogenous technology parameters in the second stage, their consequent incorporation into MAGNET in the third stage and deriving projections of food security under different policy scenarios in the fourth stage.The contribution of METCAFOS to science is two-fold: firstly it aims at enriching the weak empirical evidence on endogenous and factor-biased technical change in agriculture. Second, it contributes to the CGE literature, by incorporating endogenous technical change in a global CGE model.METCAFOS will bring important contributions to European Excellence by addressing issues that are important to ascertain food security for the decades to come. The importance of these topics has been recognized by the EU in the European policies of Food and Nutrition Security as well as in several research programs, including the FP-7 Project ‘Food Secure’, to which the METCAFOS projec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'A Training Network on Designing Novel Bio-based Fibre Products for Targeted Advanced Properties and New Applications'.

assistant: **Concept**

FibreNet will train young fibre-professionals having multidisciplinary view to develop sustainable bio-based fibre products with tailored properties for different application fields in both academic and non-academic sectors. Bio-based fibre products are one of the corner-stones in the European bio-based industry corresponding to 12% of the employment in manufacturing. The industry, including such sectors as packaging, paper, biocomposites and biomedical and hygienic textiles, is currently undergoing a fundamental transformation in order to respond to the competition raised i) by low-wage countries and ii) by fossil-based materials. A common consensus in Europe is that to remain competitive and sustain the bio-based fibre industries in Europe, we should focus on developing new high added value products that have specific functionalities but reduced environmental impacts.In fibre-based products, developing new properties and improving the performance are, however, typically long and time-consuming processes. They usually involve massive and expensive laboratory and pilot-scale trials, which are followed by statistical analyses. There is a particular knowledge gap in understanding the influence of fibre and fibre interface properties on the mechanical properties of the end-product especially when developing products with tailored performance and functionalities. In addition to the research gap, there is a training gap in Europe, as we do not currently have a training programme which would educate professionals having a skill set needed for the fibre-centered approach that we propose in FibreNet.To fill the research and training gaps, we propose here a unique training and research network which provides and further develops knowhow, methods and tools in functionalization, c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Miltefosine for leishmaniasis: molecular basis of mechanisms of action, resistance and combination therapy (MILTLEISH)' (MILTLEISH) targeting Fifth Framework.

assistant: **Abstract**

Miltefosine, an alkylphospholipid first developed as an anticancer drug, has been shown to have activity against Leis mania species and is a new oral drug for the treatment of visceral leishmaniasis. There is little understanding of the mechanism(s) of action or resistance of this drug in Leis mania. This project will characterise drug targets and resistance mechanisms in L.donovani through molecular/biochemical techniques and chemical structure-activity studies. Results will be used to design strategies to avoid or overcome drug resistance, including drug combinations. Target characterisation will be used as the basis for the identification of further antiprotozoal drugs.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Optimisation of Structural Connections for Noise and Vibration Reduction' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Mechanical joints play a significant role in vibration transfer and damping in structures, and therefore in noise radiation. However, the development of the joining technologies welding, riveting, bolting, bonding, etc. has been always influenced by manufacturing and structural integrity issues: as a consequence, these technologies are not optimised for an efficient vibration reduction. The present day knowledge on vibration properties of joints is largely insufficient to understand the behavior of joints in mid frequency range (100 500 Hz) which is the most important part of audible zone (highest ear sensitivity) when typical mechanical structures like cars or machines are concerned. Poor knowledge of transmission and damping properties of joints forces industry to carry out costly experimental work for optimising the shape, location and volume of noise damping layers. The project targets four industrial sectors: glass industry, car manufacturers, domestic appliances and engine driven machinery. Industrial objectives of the project are:  To cut down by 20% noise transmission by existing joints through optimisation of their implementation.  To increase the distributed damping produced by the joints in complex structures, and consequently to reduce by at least 20% the quantity of added damping materials necessary for achieving given performance.  To reduce the spreading of noise emission of mass products.  To reduce prototype development time and cost, by creating realistic computation and experimental models.  To develop dissipative smart joints for increased vibroacoustic performance. This project is innovative at four levels: 1. New measurement and characterisation of joints alone and embedded in structures:  Characterisation of single joints will be done by using inv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Developing innovative method for recycling used chip board furniture and plastics by producing new environment friendly reusable multipurpose composite material' (FURNITREUSE) under Seventh Framework.

assistant: **Objectives**

Each year thousands of tons wood based furniture including scrapped particle board and panels end their lives being thrown away by their users. At present there is no effective method for utilizing such waste other then dumping in landfills or incineration. This however means more space on landfills needed for storage of waste or contributes to the global warming by generating carbon dioxide and multitudes of potentially harmful substances released while combusting plates painted with different lacquers and surface varnishes. In parallel, plastics such as ABS used in desktop computers, screens and peripherals pose another challenge for recyclers. Currently after being separated from metal and electronic components they are crushed and milled locally, and then delivered for final recycling. Unlike with other plastics such polyethylene, this method only moves the problem away (often sending them outside Europe) without solving it accordingly. To meet the need it is proposed to blend crushed particle boards and plastics such as ABS in strictly controlled process deploying innovative heating technique to obtain a new type of a composite material. The range of proposed application of the composite material is vast including first applications in transportation (replacement of wood pallets) and garden infrastructure. The proposed process is environmentally friendly as no chemical compounds needs to be added to activate and control it. The early experiments with this new composite material confirmed on its expected physical and mechanical characteristics. It is further foreseen this new composite material will be further recycled as it reaches the end of life time. The use of proposed technology can inevitably change the recycling practices and can generate additional revenue
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'PRactical Implementation of Coexistence in Europe' in the context of a Seventh Framework call.

assistant: **Objectives**

Coexistence is still a controversial topic within the EU. Member States, farmers, and participants within the food chain have expressed an interest on the implications of different coexistence polices on costs, feasibility of achieving segregated supply chains, as well as implications for labeling and traceability. While a number of issues have already been addressed in previous projects, information about feasible and cost-effective coexistence measures at farm and supply chain level is still missing. PRICE will investigate the cost of coexistence practices in a number of Member States including the innovative solutions chosen by farmers to reduce coexistence compliance costs. A software module based on models resulting from previous projects (Co-Extra, SIGMEA) will be further developed with the aim to combine the natural science-based knowledge of cross pollination including biological containment methods at farm and regional level with solutions based on farmers’ knowledge and experience with co-existence measures. The software module will be tested in the field, used to systematically analyze different strategies for achieving coexistence, and developed into a user-friendly decision-support tool for stakeholders (e.g. farmers, grain handlers). Implications for traceability and labeling at farm and regional level will also be assessed. The risk of adventitious presence of GM events in GMO-free commodities is also important within international supply chains of agricultural commodities. PRICE outlines several scenarios about the evolution of the global market of GMO-free commodities taking into account a number of important parameters (e.g. prices, compliance costs) supported by two detailed case studies. A wide range of stakeholders participate form the start of the