RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Constructing Intermolecular Potentials by Combining Physics and Machine Learning' in the context of a Horizon 2020 call.

assistant: **Objectives**

Statistical-learning approaches are emerging as powerful alternatives to direct approaches to solving the electronic Schrödinger equation for determining the energy and other properties of molecules. Despite the recent success of methods like deep neural networks, these methods are limited to relatively small molecules. The issue is that predicting long-range intermolecular interactions with machine learning requires sampling the vast diversity of chemical environments that occur on an extended length scale, leading to a combinatorial explosion in the amount of training data that is required. To solve this problem, the functional form of the long-range interactions is taken from physical models, but the parameters that enter those expressions (atomic charges/multipoles; induced charges/multipoles; van der Waals coefficients) are determined by combining physical insight with machine learning. In this model, machine learning is used only to predict short-range phenomena like the dependence of atomic charges/multipoles on the molecular structure and the dependence of induced atomic charges/multipoles on the local electric field. The resulting machine-learned physically-motivated atomistic intermolecular potentials are valid for molecules of any size, but only require training data from small- and medium-sized molecules.This development will provide molecular energies with the accuracy of quantum methods, at the computational cost of classical molecular mechanics approaches. This not only allows one to compute interaction energies for large molecules (e.g., the binding energy between a drug and a receptor), but allows the computational screening of molecules based on computed interaction energies. In addition to its transformative computational utility, this pioneering stra
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Quantum Correlations in Complex Systems', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Quantum correlations in complex systems (QUACOCOS) constitute a key element of modern quantum information theory. This interdisciplinary field combines many concepts and tools from various mathematical and physical areas of research, ranging from complexity theory to quantum mechanics of large systems. Quantum correlations and entanglement are at the heart of many of the possible applications of quantum information theory. They provide the potential for unconditionally secure quantum cryptography and communication, are required for measurement based quantum computation and are involved in most of the famous quantum algorithms outperforming all classical equivalents. Furthermore these correlations are also fundamental to the physics of large and complex systems. Their role in condensed matter systems, such as e.g. phase transitions, is undoubted, in ionization procedures of quantum gases is commonly accepted and their potential involvement in complex biological systems, such as e.g. DNA and light harvesting complexes, is still subject to a controversial debate.This project aims at first developing the mathematical tools required for a thorough analysis of quantum correlations and entanglement in complex systems. These shall then be used to address many open questions in the physics of large complex systems and investigate potential applications thereof in quantum information science. The results are expected to shed light on the actual role entanglement and correlations play in biological systems, condensed matter systems and quantum algorithms.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Visualising how proteins fold DNA into topologically associating domains in single human cells' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

How can phenotypic variations emerge from cells that carry the same genetic information? It is one of today’s great challenges to understand how genetic information is modulated inside the cell. Over the last decade, insight from genome-wide proximity-based ligation approaches revealed that the genome is organised in a hierarchical manner with the help of structuring proteins, and that this spatial organisation regulates the core functions of the genome, such as transcription, replication and repair. In this context, topologically associating domains (TADs) were identified as fundamental and functional building blocks of chromatin organisation above the nucleosome level. Despite its vital importance, our current understanding of the spatial organisation of TADs remains largely enigmatic. With the advent of super-resolution microscopy, tools are now available for studying genomic structures and their functional dynamics in situ at a resolution of 10 nm which corresponds to the size of a few nucleosomes.The goal of this project is to reveal the principles of TAD organisation in human cells. To achieve this, I will employ a multidisciplinary imaging-based approach. I will simultaneously visualise the DNA backbone of TADs and architectural proteins involved in TAD structure applying 3D super-resolution microscopy. I will focus on the key TAD organisers CTCF and Cohesin, as well as on Mediator and Condensin II. Additionally, I will directly study their individual structuring function for TADs by their acute depletion. Integrating these data with quantitative measurements of absolute protein copy numbers, I will derive a data-driven model of inner TAD organisation in cells. These studies will provide the first 3D description of this fundamental chromatin super-structure and w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Presynaptic and astrocytic role of Amyloid precursor protein signaling in the hippocampus' (ABETAPRESYNASTRO).

assistant: **Concept**

Amyloid beta peptide (Abeta) is a normal product of the amyloid precursor protein (APP) proteolysis in the brain. While Abeta synaptotoxicity has been extensively studied as central to Alzheimer's disease (AD) pathogenesis, the mechanisms by which physiological Abeta regulates synapse function remain unknown. Utilizing two-photon excitation laser scanning microscopy combined with fluorescence lifetime imaging, FM-based imaging of synaptic vesicle recycling at the single-synapse level and electrophysiology, I aim to explore the molecular mechanisms modulating synaptic and astrocytic properties by physiological Abeta signaling and its effects on neuronal integration in acute hippocampus slice preparations.I will investigate the potentiation of presynaptic strength by Abeta and the transducing mechanism by answering the following questions: In the hippocampus, is the Abeta-dependent potentiation of neurotransmission synapse-specific? Can APP molecules form homodimers at presynaptic and astrocytic plasma membranes? Do local changes in the conformation of APP complexes convey intracellularly the Abeta signal? I will also investigate which effectors downstream to presynaptic APP dimers are modulated to induce Abeta-dependent potentiation of neurotransmission. I will measure the distance range at which axon-released Abeta regulates presynaptic functions during neuronal activity. With electrophysiological techniques, I will characterize the effects of Abeta on the functional input-output relationship in the hippocampal network. I will finally ask whether APP molecules also exist as dimers in astrocytes and whether APP conformation is dependent on Abeta levels and on membrane specialization in the vicinity of synaptic contacts.At the end of the project, the training in neuroimag
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Arabic Linguistic Discourse in the Making' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

The ALiDiM project proposes a metalinguistic analysis of the process of standardization of Classical Arabic as it has been described by early Arabic scholars.By analyzing the earliest Arabic grammatical texts under one metalinguistic roof, this project aims to find new ways to account for and analyze texts that challenge conventional conceptions of the origins of the Arabic linguistic tradition. Embedding linguistic production into a wider cultural framework, the project introduces methodological innovations by devising an interdisciplinary approach. The investigation will focus on the metalinguistic process of language description itself, rather than on the linguistic features described. With the objective to develop an unconventional new reading of the origin and formation of the Arabic linguistic tradition, the ALiDiM project will explore a variegated corpus of Arabic grammatical and lexicographical sources and picture the narratives presented by early Arabic scholars.The focus will be on identifying, tracing, and elaborating the earliest stages of formation of the Arabic linguistic tradition, through a reconstruction of the internal factors that gave rise to the emergence of the linguistic studies as well as the points of convergence between the Arabic and neighboring traditions.The ALiDiM project will trace origins and receptions of the linguistic themes, identifying the factors that altogether contributed to the process of language standardization of Classical Arabic. The methodology applied by the early Arabic scholars will also be studied with a twofold approach that accounts for both the local Arab-Islamic framework and possible external influences.Research data will be made available via the project’s website as a digital corpus of TEI-encoded, semantically-an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'A Novel System for the Production of World's First Micro Ball Grid Array (µBGA) Spheres for enabling the EU Electronics Industry to produce smaller electronics goods'.

assistant: **Objectives**

There is relentless consumer demand for electronics equipment offering miniaturisation with higher functionality (e.g. cell phones playing music and movies whilst also offering email/SMS/camera functions). The industry is therefore continuously aiming for increases in integrated circuit miniaturization, processor speeds and circuit densities. The resultant increasing numbers of ever finer features on the silicon chip, and the need to electrically connect to them has stretched conventional wired or leaded electronics interconnect technology to its limits. This trend of miniaturisation with higher functionality looks set to continue, requiring fundamental advances in device electrical interconnect and mounting technology. Ball Grid Arrays (BGAs) is a key technology that simultaneously addresses the requirements for high density fine feature electrical interconnect and physical attachment of silicon chip devices. BGA is a 2-D array of miniature solder alloy spheres under the silicon chip that provides both electrical connection and mechanical attachment to a mounting socket or circuit board. The small diameter of the solder alloy spheres reduces electrical resistance and capacitance and helps to preserve electrical signal integrity. BGA technology facilitates a reduction in the silicon chip package size, better heat dissipation, and greater module (circuit) densities. Typical mobile phones and laptops contain 3,000 and 6,000 BGAs respectively. These BGAs are inside CPU, RAM, DSP, Memory sticks, Consumer electronic etc. The μBGAS project aims at wider SME companies who are interested in the development of novel production techniques for producing μBGAs of less than 150μm. The μBGAs system is targeted at all electronic product producing SME companies where miniaturisation is
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'SinGLe Sign-on eGovernAnce paradigm based on a distributed file exchange network for Security, transparency, cost effectiveness and truSt' in the context of a Horizon 2020 call.

assistant: **Objectives**

The rapid growth of Information and Communication Technology (ICT) and its ubiquitous presence in our everyday life has significantly affected the way government services are delivered today. This poses constant challenges to safeguard the data confidentiality and integrity of e-government services, while increasing its adoption and usage by citizens and businesses. GLASS caters for a 'European Common Services Web', bringing closer together citizens, businesses and European governments. The project introduces a citizen-centric e-governance model that enables beneficiaries to participate in a network for big data exchange and service delivery, which is by design digital, efficient, cost-effective, interoperable, cross-border, secure and promotes the once-only priority. The GLASS solution comprises (i) a distributed file storage system, capable of addressing the complexity of the processes and their high demand on resources; (ii) a distributed ledger, which records every transaction among users to increase the overall transparency and trustworthiness; (iii) a distributed application (dapp) ecosystem for delivering mobile services tailored to the needs of its users; (iv) a single sign-on Wallet as a Service (WaaS) platform responsible for managing multiple services provided by each dapp; and (v) a Middleware Gateway Framework, responsible for the establishment of secure communication pathways among operational stakeholders and the integration of already existing e-governance systems with newly developed ones. GLASS brings together twelve (12) interdisciplinary partners from eight (8) countries to deliver a novel e-governance model and address the challenges that governance structures in the EU are currently facing - from divergent and legal groundwork to physical and techn
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'How Issues Make the News: A Comparative Analysis of the Causes and Consequences of Media Attention in Belgium, France, Switzerland, and the United States' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Attention drives politics. At every level of government and in the public realm, the political process is shaped by which issues are discussed and which are ignored. Media attention has an especially strong influence. The amount and type of news coverage an issue receives directly affects the amount and type of public concern and government response paid to the issue. Yet media attention is not a fixed process; it varies widely across the political and social contexts of different countries. We (Amber Boydstun at UC Davis in the United States and Stefaan Walgrave at the University of Antwerp in Belgium) propose a systematic analysis of media attention in Belgium, France, Switzerland, and the United States. We are part of the Comparative Policy Agendas Project, an international network of scholars using a common coding scheme to collect data on the governmental and media agendas of more than a dozen countries (and counting). Boydstun was one of the first scholars to apply this common coding scheme to the news. She collected all front-page stories in the US New York Times, 1996–2006 (some 30,000 stories), classifying each story according to the primary policy or non-policy issue being discussed (e.g., abortion, immigration, war, sports, weather). Walgrave is at the forefront of the effort to extend this analysis to the EU, and under his guidance the Belgian, French, and Swiss teams have already completed large datasets of news stories from their home countries, classified using this same coding scheme. We will compare these apples-to-apples datasets of media attention, using statistical analysis to examine three questions: 1) How does media attention vary by country? 2) What factors (e.g., media market competition, political party setup) drive these cross-national differe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Race to the bottom? Family labour, household livelihood and consumption in the relocation of global cotton manufacturing, ca. 1750-1990' (TextileLab) targeting Horizon 2020.

assistant: **Abstract**

Globalization and the shift of industries and jobs to low-wage countries are topical political issues, but have deep historical roots. For long, cotton manufacturing has been central in global trade and industrial relocation. Textile production has existed almost everywhere, but its major export centres have relocated in the past 250 years, notably from Asia to Europe/the US, then back to Asia. When and why these shifts occur is however still poorly understood. Reducing labour costs has been argued to be central in this ‘race to the bottom’, but this does not explain why textile production was resilient in some regions and periods, and not in others.This project explores the macro-economic global relocation of textile production from a micro-level perspective: households’ labour and consumption decisions. It proposes an in-depth comparative study of changes in labour allocation and consumption at the household level, to deepen macro-level studies on global textile production. Its main question is to what extent, and how, gender divisions of work, households’ multiple livelihood strategies, and local consumption patterns have influenced the continuation and disappearance of textile manufacturing over time and space? Its empirical contribution is a systematic long-term global comparison of nominal and real textile wages in the context of total household income. Its methodological innovation is to comparatively study labour costs, skill formation and income over time from the micro- perspective of the household, using quantitative and qualitative approaches from several academic fields. Its analytical value is to study interactions between causal mechanisms on the macro-economic level (markets, institutions) and the location of textile manufacturing, with households’ produ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The Queen's Post: The Form, Function, and Power of Early Tudor Queens' Correspondence' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

The Queens' Post project provides the first large-scale analysis of the form, function, and power of early Tudor queens' correspondence. This project investigates the letters of nine important early Tudor queens, including the wife of Henry VII (d.1509), Elizabeth of York (d.1603), Henry VII's daughters Margaret Tudor (d. 1541) and Mary Tudor Brandon (d.1533), and the wives of Henry VIII (d.1547): Katherine of Aragon (d. 1536), Anne Boleyn (c.1536), Jane Seymour (d.1537), Katherine Howard (d.1542), Anne of Cleeves (d.1557), and Katherine Parr (d.1548). Using an innovative, interdisciplinary methodology - employing methods from linguistics, literary studies, archival studies, material culture, gender studies, and diplomatic history - The Queens' Post will advance our understanding of the nature and power of royal women's voices and writings of the past, and reconsider the power and position queens held in early modern politics and diplomacy. The results of this project will have distinctive scientific and societal impact which will be disseminated via a range of outputs aimed at both academic and non-academic audiences. This includes a project monograph, an edited collection, a symposia, a podcast, and various other outreach activities. The project will also provide a significant methodological contribution to letter-writing studies, by developing a cutting-edge, interdisciplinary framework of analysis to investigate the language, materiality, and delivery of historical correspondence across a network of writers.


**Keywords:** Manuscript Studies; Literary studies; Queenship Studies.