RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Single cell biophysics of bacterial cell shape' (BACTOSHAPE) targeting Horizon 2020.

assistant: **Abstract**

In bacteria, the rigid external cell wall (CW) and the intracellular actin-like (MreB) cytoskeleton are major determinants of cell shape. Synthesis and chemical composition of the CW, a three dimensional polymer network that is one of the most prominent targets for antibiotics, are well understood. However, despite decades of study, little is known about the complex CW ultrastructure and the molecular mechanisms that control cell shape in time and space. MreB homologues assemble into dynamic membrane-associated structures thought to control shape by serving as organizers for the movement and assembly of macromolecular machineries responsible for CW biogenesis. However, the mechanistic details used by the MreB cytoskeleton to fulfill this role remain to be elucidated. We will combine powerful genetic tools available in the model Gram-positive bacterium Bacillus subtilis with modern high-resolution fluorescence microscopy techniques and atomic force microscopy (AFM) to study the role of the MreB cytoskeleton and CW synthesis proteins in cell shape determination and maintenance. Additionally, the role of mechanical forces in the control of CW organization will be evaluated.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Climate Change and Marine Ecosystem Research Results'.

assistant: **Innovation**

Although there is no certainty regarding the precise nature and rate of future climate change, even the most moderate scenarios predict a continuing change of the marine environment, with associated major environmental and social impacts. To prepare society for the necessary mitigation and adaptation measures, the awareness of citizens to research results, both certainties and uncertainties, in this specific area should be raised. During the last years, much new information has been gathered in large EU-funded research, but to date this information has not been synthesized nor has it become an important part of public knowledge. The aim of this proposal is to make a synthesis of EU research results on the impacts of climate change on the marine environment and to make this knowledge and its socio-economic consequences better known to European citizens and society at large. Together with expert representatives of major Networks of Excellence, large EU projects and research networks, we will produce a state-of-the-art overview of European research results on the effects of climate change on marine environment. An up-to-date overview of public knowledge and perception on the effects of climate change on marine environments and their socio-economic consequences will be produced by means of polls and questionnaires. The results will be used to identify the main issues to be addressed and the best practices to be used during the outreach activities. Enhancement of public knowledge on climate change impacts on the marine environment, including the socio-economic consequences, will be achieved by means of challenging and innovative tools such as an interactive Pan-European conference at the end of 2010 and a high-quality internet-based portal within an e-learning platform. Thes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Assessment of risk-factors for early loosening in cemented total hip replacement', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The annual implantation rate of hip prostheses is estimated to be about million worldwide, and the success rate is about 90 percent after 10 years post-operatively. The usual cause of failure is mechanical loosening of the implant. These loosened components can be detected as they migrate within the bone. Recently, accurate migration measuring techniques have been introduced, which are capable of detecting loosened components) and can identify these as future revisions, already within one year after the implantation. This has led to the hypothesis that loosening is dominated by factors which can be assessed immediately after the operation. The aim of this study is to investigate this hypothesis. Therefore, patient data, patient-specific computer simulation methods, and laboratory experiments are combined to determine which factors are responsible for early loosening of the component.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Tuning molecular friction and adhesion by atomic/chemical design'.

assistant: **Objectives**

Friction is a phenomenon which is present in our everyday life although we tend to remember it only when it is nearly absent such as when “slipping on a banana peel”. Its presence across disparate length scales (earthquakes, car engines down to molecular machines) reminds us of its ubiquity which endows friction of an utmost practical importance. Therefore, attempts to control it are almost as old as civilization. Interestingly, during the past decades we have witnessed a growing progress in miniaturization of devices down to the nanometer scale. “Special problems occur when things get small […] and it might turn out to be advantages if we knew how to design for them”, said Feynman when discussing the prospects of building “infinitesimal machinery”. To achieve this goal, and to design efficient molecular nano-engines, it becomes imperative to know how friction at a molecular level can be controlled. In this project we propose to address this challenge by tuning molecular friction and adhesion via atomic/chemical design. Specifically, we shall study the lifting and sliding of two template molecules (porphyrin and terpyridine) over a Silver (111) surface. These molecules contain substituents groups that act as spinning molecular wheels when sliding over a surface. By proper modifications of these groups (wheels) we can tune the grip/drift response and the efficiency of the ball bearing over which the molecular wheel spins. Here we aim to provide an atomic level understanding of these processes by combining state-of-the-art molecular dynamics simulations with high resolution scanning-probe microscopy experiments conducted in ultra-high-vacuum conditions at low temperature. This will constitute a major step forward in our understanding of dissipation processes at the nanosc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Flexible Heat and Power, Connecting heat and power networks by harnessing the complexity in distributed thermal flexibility.'.

assistant: **Objectives**

The annual space heating and cooling energy consumption in Europe is almost 3,500TWh. In 2012, in EU28 the electricity consumption ratio was around the 20% of the total energy consumption, from which 30% was consumed in the residential and 30% in the services sectors. From these proportions, air conditioning represents 17% of the total electricity consumption in the EU27 residential buildings. In the EU tertiary sector the electric space and water heating system represent 19.22%, the ventilation 12.47%, the commercial refrigeration 8.57% and the air conditioning 2.86% of the buildings electricity consumption. Heating, ventilation and air conditioning system’s electricity consumption of a building can represent between the 30% and 40% of the total energy consumption.The inertia of these power to heat solutions constitute an enormous potential for electric flexibility usable for absorbing the excess of renewable generation and avoiding curtailment while managing local power congestion, voltage stability in the grid and avoiding reversal power flows, as well as minimizing RES production imbalance. That is, DER with thermal inertia can provide services to RES owners, grid operators, aggregators and actors on the power market, while saving energy in the buildings. In fact, flexibility harnessing using heat to power solutions enables to deploy large-scale renewable throughout Europe successfully.The Flexible Heat and Power (FHP) project will develop a Power-to-Heat (and Cooling) solution package that manages this complexity through an easily accessible interface aimed at buildings and power grid actors. A practical prototype will be developed and deployed in two different demonstration scenarios in The Netherlands and Sweden representing diverse parts of the European power gr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Core monitoring techniques and experimental validation and demonstration' (CORTEX).

assistant: **Concept**

The CORTEX project aims at developing an innovative core monitoring technique that allows detecting anomalies in nuclear reactors, such as excessive vibrations of core internals, flow blockage, coolant inlet perturbations, etc. The technique will be based on primarily using the inherent fluctuations in neutron flux recorded by in-core and ex-core instrumentation, from which the anomalies will be differentiated depending on their type, location and characteristics. The method is non-intrusive and does not require any external perturbation of the system. The project will result in a deepened understanding of the physical processes involved. This will allow utilities to detect operational problems at a very early stage and to take proper actions before such problems have any adverse effect on plant safety and reliability. With an ageing fleet of nuclear reactors utilizing more challenging fuel assembly designs, core loadings, and operating more often in load-follow, new operational problems have been observed during the last decade and will become more frequent in the future. By making the detection and characterization of anomalies possible, the availability of nuclear-generated electricity will be further improved. This will contribute to a lowering of the CO2 footprint to the environment and to a higher availability of cheap base-load electricity to the consumers. By implementing the technique in the existing fleet of reactors, the technique will have a major impact. Moreover, the technique, being generic in nature, can be applied to future reactor types and designs. In order to develop a method that can reach a high Technology Readiness Level, the consortium was strategically structured around the required core expertise from all the necessary actors of the nuclear ind
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Widening the use of European solar thermal technologies in Mediterranean countries following the successful model of Greece and Cyprus. Part A: Spain, Portugal' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

The project aims at facilitating the way to the market for high efficiency, proven solar thermal systems, and alleviating the anticipated consequences of limited use of solar thermal systems in the south-western Mediterranean countries, Spain, Portugal, France, Italy. The project is addressed to European markets with very limited penetration of solar energy where from the technological, economic, social and aesthetic point of view it is not justified.The objectives of the proposed action are to:- Setup an information exchange mechanism- Elaborate of working papers addressing the introduction of preferred technologies and relevant legislative and economic issues
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Elucidating the cellular basis of therapeutic resistance in Crohn's disease', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Crohn´s Disease (CD) is a chronic inflammatory disease that affects the gastrointestinal tract, affecting millions of people worldwide and presenting a considerable economic burden to health systems. CD has a serious impact in quality of life, not just physically, but also emotionally and socially. Pathogenesis results from a complex interaction between environmental factors, microbiome, genome, and inflammatory system, leading to disruption of the intestinal mucosa. The imbalance between inflammatory and regulatory cells in maintaining an active disease is well known, and most therapies aim to stop the cascade of inflammatory and pro-inflammatory cytokines (i.e. TNF-blockade). One of the major challenges for treatment is the fact that not all patients respond to therapy. Moreover, the mechanisms behind resistance are still not completely understood, making it hard to correctly stratify patients as responders and non-responders at time of diagnosis. We aim to elucidate changes in immune regulation that explain primary response failure to TNF-blockade in CD. We hypothesise that dysfunction of regulatory cells may prevent reinstatement of homeostasis following inflammation targeting. We will establish single-cell transcriptomics of immune cells from biopsies at the time of diagnosis, as well as in patients responding to treatment and non-responders. Then, we will use computational methods to investigate how immune cells change with time, acquiring a state supporting therapeutic resistance. Moreover, we will illuminate the relationship between immune dysregulation and anatomic niches using spatial transcriptomics. Finally, we will analyse paired peripheral blood samples, for the identification of putative biomarkers for stratification of patients according to TNF-blockade
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'AI-Driven Rapid Condition Assessment for Masonry Arch Bridges' to be submitted under Horizon Europe.

assistant: **Abstract**

Masonry Arch Bridge (MAB) still plays a critical role within railway and roadway networks in Europe and worldwide. MABs constitute the majority of the European bridge stock. These structures were mainly built following empirical rules and were not designed to resist current traffic loading. Furthermore, nowadays, MABs are confronting the challenges of climate change and severe environmental conditions that degrade their performance. An accurate assessment of these complex structural systems represents a crucial step to preventing future failures and preserving them for the next generations. AIdaMArch introduces a tailored structural health monitoring approach that leverages a two-step data-driven methodology based on Long Short Term Memory (LSTM) models.The LSTM model enhances structural health monitoring by rapidly analyzing large amounts of sequential sensor data for real-time, continuous and adaptive monitoring of structures. MAB sensor measurements are not able to be analyzed by data-driven methods due to a lack of proper training data. To simulate the structural behaviour, a novel numerical model will be developed, and the data set will be augmented by a cyclic generative adversarial network for a higher level of applicability. AIdaMArch possesses the versatility of using a two-step data-driven method to not only detect anomalies (damage detection) but also extend its application to identify the severity of damage in MABs by the small number of measurements. The main goal of this proposal is a continuous, rapid, and accurate methodology for the health monitoring of MABs. To ensure the successful implementation of the project, Dr Emadi will conduct research at the Imperial College of London, with the guidance of Prof. Macorini, a leading scholar in the field, as a m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Urban Metamorphosis of the community of a Medieval African capital city' (UMMA) under Horizon 2020.

assistant: **Objectives**

UMMA (Arab. أمة - community) is a multidisciplinary project aimed as the first study of the liminal phases of a Christian African community inhabiting Dongola, the capital city of of Makuria (modern Sudan). It will concern the twilight of Christian Dongola and the metamorphosis of its urban community into a new entity organised along different social and religious paradigms. The project will investigate the impact between the weakening of the central authority and migrations of Islamic Arab tribes on the kingdom’s capital city and its community. The notion that the project intends to investigate is that a complete breakdown of this urban organism and its hinterland was avoided thanks to cooperation established between the remaining local community and migrant population groups arriving in the period under consideration. The project will seek to identify strategies ofinteraction between the local community and the newcomers, as well as patterns of survival of the old traditions on household level. UMMA will lay foundations for further enquiries into evolution of precolonial African communities and provoke a general discussion on social changes in urban environments. It will unfold a whole new research perspective on the period from the gradual decline of the kingdom of Makuria (14th-15th cent. CE) to the Egyptian invasion in 1820, which is virtually absent from scholarly enquiry to date.UMMA brings together specialists from several disciplines to carry out an exemplary archaeological project to set the standards for future archaeological research on late medieval and early modern Sudan. The project will combine methods of inquiry used in disciplines like history, archaeology, geophysics, chemistry and physics to obtain a multifaceted, cross-disciplinary perspective on th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Bauhaus Bites: Positive Food Environments Fortified with Nature-Based Solutions and New European Bauhaus' (2021-2027), addressing dissemination and exploitation.

assistant: **Impact**

The project will deliver urban food system transformation via Bauhaus Bites (BB) Food Environments, co-created and demonstrated in 7 cities at different levels of societal readiness, their transferability discussed with sister projects and European/global networks, and the results summarised in a Playbook for broad adoption. Bauhaus Bites Food Environments are urban and peri-urban ecosystems that commit to implementing sustainable healthy diets, amplified by the New European Bauhaus, and fortified with Nature-Based Solutions, ensuring that the transformed food environments of tomorrow are sustainable, inclusive and beautiful.By merging the key perspectives of European and global strategies such as the Farm to Fork and FOOD 2030 strategies, the Planetary Health Diet and the Planetary Health Diets with the New European Bauhaus values and principles, Bauhaus Bites offers a unique approach not yet seen in food system transformation projects, that will reimagine these food environments together with local, culturally diverse communities, customised to meet their needs, and anchored in social meeting spaces that carry meaning for them. The project will co-create BB Food environments in 3 Trailblazers (Birmingham, Fundo, Zagreb) and 4 Twins (Murska Sobota, Ostend, Palermo, Sarajevo) with different geographies, sizes, demographic challenges and societal readiness, boost mutual learning through a Community of Practice, document their added value with science-based indicators to inform high-level policy-making, test them for transferability with European/global networks, and summarise the learnings, guidelines, methods and examples in a Playbook. The BB approach will be based on inclusive participation and co-creation, including city and regional authorities, community- and busin