RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'IMPROVING MODELLING METHODS TO PRODUCE CLIMATE SERVICES FOR RESILIENT EUROPEAN SEAS AND COASTS IN A DECADAL TO MULTI-DECADAL HORIZON'.

assistant: **Objectives**

Delivering validated climate services for resilient European Sea on a decadal to multi-decadal horizon is a challenge. RIVIERADE brings together the scientific communities geared into CORDEX and the Copernicus Marine Service and capitalizes on their unique scientific experience to develop and implement a pre-operational and replicable multi-model framework and protocols to produce, downscale, assess and deliver state-of-the-art decadal predictions and multi-decadal projections of climate change and related impacts on marine ecosystems, covering the basin scale and the coastal areas, up to, and including, development and demonstration of climate services.RIVIERADE will target three European Seas (Baltic, Black, Mediterranean), to produce data and information for ocean health, sustainable blue economy, and coastal climate risks, downstreaming the data flow from climate ensembles to coastal areas at different spatial resolutions and for selected areas, in a circular process based on users and stakeholders engagement, co-design and assessment of innovative climate services. The proposed methodology will employ high-resolution regional Earth Systems, ocean, marine ecosystem, and impact models of different complexity and will include both traditional and new ocean modelling approaches with the final objective of delivering: (i) coordinated and harmonized multi-model datasets of high-resolution decadal and multi-decadal scenario simulations for the three European target seas (ii) demonstrators of climate services at European Sea basin scale (3 seas), coastal regional (4 subregional areas) and local (4 local use cases) scales.These datasets, together with the framework proposed to produce the coastal climate services, and the portfolio of Delivering validated climate services f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Repair of Junctional Atrioventricular Conduction and Impulse Formation'.

assistant: **Innovation**

Background: To bypass hardware-related complication there have been substantial efforts to create biological pacemakers. Effective strategies have been identified and are now being refined for delivery of long-term function and clinical application. Yet, currently developed biological pacemakers only provide pacing to atrium or ventricle thereby aiming at ~20% of pacemaker patients. To unleash the full potential of biological pacing, targeting virtually every pacemaker patient, effective repair of atrio-ventricular (AV) conduction is crucial. With the arrival of advanced stem cell-based therapies, now is the time to meet this important challenge. Objective: To develop a stem cell-based therapy that restores impulse formation and conduction at the interface between atrium and ventricle.Approach: Human induced pluripotent stem cells (hiPSCs) will be used to produce cells with hallmark features of AV nodal cells. After in vitro testing, these cells will be implanted in vivo (together with biomaterials) to form AV bypass tracts in sheep that are in permanent AV block. In this setting, approaches will be tested for their ability to bridge electrical activity from the atrium to ventricle and protect the ventricle from atrial tachycardia. The final steps of this project focuses on the development of dedicated implantation catheters (in collaboration with Medtronic) and optimization of cellular constructs that are regulatory compliant and ready for clinical testing.Impact: By developing novel therapies to re-establish AV impulse formation and conduction I will broaden the application area of biological pacing to nearly all patients. In Europe ~300.000 pacemakers are implanted annually representing cots of ~8 billion Euros. Five per cent of these implantations result in serious
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Integrated Zero Defect Manufacturing Solution for High Value Adding Multi-stage Manufacturing systems' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Manufacturing companies are continuously facing the challenge of operating their manufacturing processes and systems in order to deliver the required production rates of high quality products of increasing complexity, with limited use and waste of resources. ""Zero Defect Manufacturing"" (ZDM) is a recent paradigm aiming at going beyond traditional six-sigma approaches in highly technology intensive and strategic European manufacturing sectors through new knowledge-based approaches. The ZDM paradigm is of key importance to manage production quality targets in advanced manufacturing industries. The implementation of this paradigm in industry requires innovative defect management and control methods, novel technologies for in-line inspection and integration of knowledge management and ICT tools for smart and sustainable decisions in complex industrial scenarios, which are not available in the market. The aim of the ForZDM project is to develop and demonstrate tools to support the rapid deployment of ZDM solutions in industry and design more competitive and robust multi-stage manufacturing systems. The proposed ZDM approach is based on the combined adoption of new knowledge-based data-gathering and root-cause analysis solutions to reduce the generation of defects as well as new on-line defect management and improved production traceability solutions to mitigate the propagation of defects along the production line stages. This will be achieved through the proper integration of innovative enabling technologies, such as cyber-physical systems, selective inspection, advanced analytics and integrated process and part-flow control solutions.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'A general equilibrium approach to decision criteria for business firms. Investment decisions and labor management under incomplete markets' in the context of a Fourth Framework call.

assistant: **Objectives**

The objective of the project is to analyze firm's behavior in an uncertain environment considering two major choices: production plans and labor contracts. The economy under consideration is characterised by incompleteness of asset markets, which means that firms cannot be insured against all kinds of future uncertainty because some financial assets are missing from the market. In particular, the project will deal with three interrelated themes: 1. The efficiency of competitive equilibrium investment decisions from a welfare point of view and from the point of view of the firm's shareholders. In both cases, equilibrium allocations are generically inefficient however there is room for Pareto improving policies. 2. The incorporation of agents strategic behavior in the stock market by assigning control rights to shares. Portfolios aiming at the control of a firm may be seen as an alternative and supplementary viewpoint - apart from the purely financial one - for explaining price formulations. This issue is closely related to firm's investment decisions in the absence of unanimity among shareholders. 3. The introduction of labor inputs in models with technological uncertainty. In this setup, the existence and the properties of equilibria defined simultaneously for the stock market, the markets for labor contracts, and the decentralised decisions of firms and households are studied. Macroeconomnic extensions of such models and policy implications can also be derived.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The spectrum of geometric operators on manifolds with singularities' to be submitted under Sixth Framework.

assistant: **Abstract**

On a compact Riemannian manifold without boundary, the Laplace and Dirac operators have discrete spectra accumulating towards infinity. The eigenvalue counting function has an asymptotic expansion depending on the volume and the dimension of the manifold. On noncompact manifolds several aspects of this theory may go wrong. In a recent paper we proved that on manifolds with conformally asymptotically cylindrical ends, a more general Weyl law holds for the eigenvalues of the Dirac operator. The goal of this p roject is to investigate whether such laws hold on other types of Riemannian manifolds with singularities, in particular manifolds with corners with conformally cuspidal ends, and conformally conical manifolds.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Modeling and targeting cell-extracellular matrix communication to revert tissue fibrosis'.

assistant: **Concept**

Skin fibrosis is a complex disorder characterized by the replacement of healthy tissue by pathological extracellular matrix (ECM). Despite its significant health burden, current treatments remain largely ineffective, leaving patients without efficient therapies. This gap is due to a limited understanding of how ECM cues and cells of the fibrotic niche co-evolve and interact over time to drive fibrosis. To address this, we will dissect how space- and time-dependent changes in ECM properties during fibrotic remodelling drive dysfunctional alterations in cell-matrix communication, thus promoting fibrosis progression. To tackle this, we propose a multidisciplinary approach merging patient samples, bioinspired hydrogels, human cells, 3D bioprinting, and high-content analysis of fibrosis at cellular, molecular and tissue levels. With this patient-centred approach, we will create a modular hydrogel library with tissue-specific and programmable properties to uncover the role of ECM cues in fibrosis. By harnessing these new insights, we will capitalize on bioprinting to create unique 3D models recreating the heterogeneity and cell dynamics in human skin fibrosis to unveil tractable targets for therapeutic purposes. Overall, this high-impact project addresses a major health challenge – identify drivers of fibrosis – leading to the development of innovative 3D models for discovering therapeutics that ultimately reverse fibrosis without disturbing tissue homeostasis.


**Keywords:** Hydrogels; Extracellular Matrix; Viscoelasticity; Skin fibrosis; In vitro Models
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Food Labelling to Advance Better Education for Life' (FLABEL) targeting Seventh Framework.

assistant: **Abstract**

Nutrition labels are potentially a major instrument for enabling consumers to make healthier food choices, but current insights into how nutrition labels are used by consumers in real-world shopping situations are limited, making the science-based formulation of new labelling policies and the evaluation of existing ones difficult. The objectives of this project are to determine how food nutrition labelling can affect dietary choices, consumer habits and food-related health issues by developing and applying an interpretation framework incorporating both the label and other factors/influences. Based on this, guidelines will be developed on use of nutrition labelling for EU policy and the food industry, especially SMEs, which will include recommendations for assessing the impact of ongoing and future legislative and voluntary food labelling schemes. These objectives will be achieved by a work programme covering an analysis of current penetration of and exposure to nutrition labels in the EU, determinants of attention to and reading of nutrition labels, determinants of consumer liking of nutrition labels, understanding how consumers infer healthiness of food products from label information in combination with other sources, in-store use of labels, and effects of label use on dietary intake. The project will draw heavily on the involvement of stakeholders from the whole food sector to ensure results with high practical relevance.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Proof of Concept study for ERC NIPD discovered biomarkers' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Scientific and medical evidence indicate that non-invasive prenatal testing, known as non-invasive prenatal testing (NIPT), is a safer alternative to invasive tests that might put the pregnancy at risk. Modern NIPT examine traces of fetal DNA in the maternal bloodstream to determine whether the fetus is at risk of chromosomal abnormalities such as, but not limited to, Down syndrome (trisomy 21), Patau syndrome (trisomy 13) and Edward’s syndrome (trisomy 18). In this ERC Proof of Concept Grant (mR-NIPD), we anticipate to correlate already discovered DNA biomarkers of the ERC NIPD (funded ERC) with biomarkers in mRNA transcripts. The method, directly related to the currently funded ERC, will use m6A-specific methylated mRNA immunoprecipitation combined with Next Generation Sequencing (MeRIP-Seq) on fetal and maternal mRNA samples. As a result, we aim to increase the number of fetal specific biomarkers and provide a novel, cost-effective non-invasive prenatal test that will be accessible to all pregnant women independent from social and economic status
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Social Resilience, Gendered Dynamics, and Local Peace in Protracted Conflicts' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

How can ‘resilient communities’ remain resilient in protracted conflicts and contribute to sustainable peace rather than to increased vulnerability to renewed conflict? How do local conflicts link to national conflicts and what are the implications for peacebuilding? What are the gender dimensions of social resilience? Is resilience always ‘a good thing’ or may it impede conflict resolution? This project pioneers an interdisciplinary research agenda into resilience building. The need for a greater analytical focus on the causes and consequences of social resilience is evident in the modest international record of peacebuilding and civilian protection. Scholarship increasingly invokes resilience terminology but lacks mature conceptual and empirical work. Building on the PI’s expertise in social resilience, communal conflict, and gender and peacebuilding, this project will establish an empirically-grounded research agenda on social resilience and sustainable peace. By providing a comparative analysis of resilience building and barriers to peace in Nigeria, South Sudan, the Central African Republic (CAR) and Kenya, the project will create a new agenda for resilience research that rests on novel conceptual development and interdisciplinary approaches to resilience combined with the systematic study of social resilience and local peace produced by an integrated team of specialist researchers. The project will involve a fieldwork-based multi-method research design that combines advanced quantitative techniques for assessing the consequences of international peacebuilding with regard to local peace and women’s empowerment with context-sensitive qualitative analysis of the often unintended consequences of social resilience and hidden barriers to local peace and changing gender
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Delivering next generation Transport Management System to European transport SMEs' to be submitted under Horizon 2020.

assistant: **Abstract**

State-of-the-art Transport Management Systems conceived in modular approaches do not provide an all-in-one solution to answer SME business-related needs more broadly. To own a holistic TMS requires a long and expensive integration and customization process which makes TMSs not affordable by SMEs who generally lack resources for it. Additionally, none of the current solutions are able to gather real time data to support real time optimization decisions.At Ruptela we are committed to developing a new, highly competitive and integrated platform providing all the necessary information to transport SMEs and representing an affordable solution for them: INTRANSYS.INTRANSYS will use our award-winning fleet tracking and management platform TrustTrack as a foundation to integrate continuously updated traffic data, tracking services, rich communication with driver and eco-driving tools into a single cloud-based application. This real-time integration will allow transport companies to optimize operations on the go 24/7.As we will offer the system as an “all-inclusive” solution, we will drastically reduce the customization and set-up process both in terms of time and costs. We will achieve this goals by providing a SaaS based pricing model adapted to SME size and usage. INTRANSYS’ ease of use, combined with our extremely competitive pricing strategy opens the door for thewidespread commercial adoption by SME transport companies who dominates the European transport market. Note that we will allow massive savings on European transport SMEs (up to 19% of all transportation processes) while contributing to the EC’s goal of forcing the reduction of CO2 emissions of the transport industry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Controlled Local Heating to Crystallize Solution-based Semiconductors for Next-Generation Solar Cells and Optoelectronics' (LOCAL-HEAT) targeting Horizon Europe.

assistant: **Abstract**

Solution-processed semiconductor thin-films have recently emerged as promising candidates for optoelectronic devices such as light-emitting diodes (LEDs), sensors and solar cells. One example is hybrid perovskite films that are processed inexpensively by crystallization from a solution and have the disruptive potential for efficient energy production and consumption. However, current crystallization methods from solution often result in uncontrolled film growth with ragged, degradation-prone grain boundaries. The lack of quality materials with large, controlled grains holds back solution-based semiconductors.The core hypothesis of LOCAL-HEAT is that controlling the fundamental crystallization kinetics of semiconductor films, when transitioning from the liquid precursor to the final solid-state, governs ultimate performance and long-term stability. This is key to creating materials that are: a) sustainable, b) stable and c) show highest performance.To achieve this challenging goal, I will control the crystallization kinetics of liquid multicomponent semiconductor inks by turning light into localized heat packages to cause confined supersaturation. This will induce seeds to crystallize the liquid precursor into high-quality films.Local heat will be realized by developing two methods: a) laser annealing by a tunable light pattern, projected on a liquid precursor film, and b) thermoplasmonic heating of plasmonic nanoparticles acting as antennas to turn incoming light into a localized heat nanobubble within a liquid ink.Achieving sustainable materials with highest quality crystallization will enable perovskite solar cells with performances >26% and stabilities of >30 years. Consequently, it will also revolutionize solution-processed semiconductors in general. LOCAL-HEAT will