RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Conservation Data Justice', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

CONDJUST will create a new research field, Conservation Data Justice, that bridges three distinct areas of enquiry: conservation prioritisation, political ecology and Data Justice. The former uses data which risk marginalising rural peoples. The latter does not yet examine conservation data. Meanwhile political ecologists do not yet consider Data Justice approaches when tackling conservation prioritisation. CONDJUST will interrogate conservation data and models, and explore the epistemic communities producing them, to develop new theories of socially just, data-driven conservation. It will challenge the colonising tendencies of prioritisation work and seek decolonising alternatives.CONDJUST is timely because ambitious new global targets seek to safeguard 30% of the planet for conservation by 2030 (and more afterwards). These plans pose risks for rural people because the data and modelling they use can contain diverse forms of bias, exclusion and omission. These risks will grow as more social media data are used in conservation prioritisation. We need insights from Data Justice to understand these dangers, and how they might be counter-acted.This project has four objectives, each with a corresponding work package. These are:1. Systematically examine the sources of bias and distortion in conservation data used in global prioritisation work.2. Use Data Justice thinking in new analyses of biodiversity conservation, and increase our understanding of socially just conservation prioritisation.3. Critically explore the construction of different epistemic communities in conservation prioritisation, and political ecology, to understand what inhibits and enhances learning between them.4. Examine how policies responding to prioritisation are shaped by, or resist, the new measures p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'REstoring myocardial repair capacity via the modulation of MAcrophage-mediated cytoKINe secretion.' (REMAKIN) under Horizon 2020.

assistant: **Objectives**

Type-2 diabetes (T2D) is a chronic condition strongly associated with cardiovascular diseases, mainly recurrent myocardial infarctions (MI), and generating enormous healthcare cost. Macrophages orchestrate the remodelling of the heart post-MI by efferocytosis-mediated cytokine secretion. Specifically, Mertk-mediated efferocytosis promotes vessel formation, tissue reperfusion and resolution of the inflammatory response via the secretion of the anti-inflammatory cytokines interleukin-10 (IL-10) and Vascular Endothelial Growth Factor-A (VEGF-A). In IR/T2D, efferocytosis-mediated cytokine secretion is impaired, leading to chronic inflammation, adverse post-MI remodelling, recurrent heart failure and excessive mortality. To date, the signalling and intracellular trafficking pathways leading to cytokines secretion are unknown, and the mechanisms of impairment during IR/T2D are unexplored. Previous therapeutic strategies focussed on repairing damaged tissue by injection of progenitor cells or modulating inflammation by cytokine injection, but both strategies gave disappointing results. In this proposal, I will define the mechanisms of efferocytosis-mediated cytokine secretion in macrophages, investigate their defects in IR/T2D and test a novel cell-based therapeutic strategy for improving recovery of T2D patients post-MI and preventing recurrence of cardiac events by restoring cytokine secretion in diabetic macrophages.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Improving risk prevention in mountains using spatial modelling of rockfall and its effect on ecosystem functioning of protection forests' (1998-2002).

assistant: **Concept**

Forest is multi-functional ecosystems, but a major function is not taken into account: the protective function against rock fall risks. The project aim is to incorporate tree mechanical behaviour in a spatial rock fall model in order to assess the efficiency of forest stands against rock fall and to produce management guidelines for sustainable rock fall hazard mitigation by mountain forests.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Shaping the social brain through early interactions' (SAPIENS) under Horizon 2020.

assistant: **Objectives**

The first three years of life are critical for children’s long-term development, health and wellbeing, since core brain functions are formed during this period and the brain is much more vulnerable to adversity, which is key for the emergence of developmental disorders (autism, attention deficit/hyperactivity disorder). Identifying the mechanisms that act during early childhood to shape individual long-term social development is essential for improving the health and wellbeing and has far-reaching consequences for social and educational policy. We propose that this key scientific problem cannot be solved without first understanding how early social exchanges tune critical brain functions in early childhood. Daily, repeated exchanges between infants and caregivers provide the substrate for the interacting influences of genes and the environment on brain development. By studying the micro-scale dynamics of early social exchanges we can revolutionise the understanding of macro-scale development of socially-relevant functions like theory of mind, language, attention, and emotion regulation. Our radically new approach puts social exchanges at the heart of brain development, which is sculpted through a complex ongoing cascade of interactions between the brain and its social environment. SAPIENS combines advances in ecological, mobile real-time brain and behaviour measurement, data modelling and artificial intelligence approaches to train a new generation of researchers in implementing these ground-breaking approaches to early social development. SAPIENS will generate revolutionary new tools for translating cutting-edge basic science into clinical diagnostic and treatment tools for developmental disorders, while engaging the public and delivering new public policy. By building
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Decentralized microfluidic in vitro diagnostic patch for pandemic control' (DECIPHER) under Horizon Europe.

assistant: **Objectives**

In vitro diagnostic (IVD) technologies have revolutionized healthcare, yet remain confined to the laboratories. This traditional approach massively failed to manage viral outbreak during the COVID-19 pandemic because it lacked quick and cost-effective diagnosis. Moreover, an urgent need was evident for bringing quantitative lab-quality diagnosis to the hands of end users (i.e., point-of-care, POC). Despite high expectations from Lab-on-Chip technologies, they failed so far to disrupt the IVD market due to their complexity, high cost, off-chip sample preparation, poor scalability, to mention a few. The DECIPHER consortium aims to revolutionize the POC IVD field by developing innovative microfluidic-based DECIPHER patch capable of both biofluids (self-)sampling via hollow microneedles (HMNs) and immediate analysis of this sample on the very same patch in a completely self-powered manner, producing quantitative result to be read out with a re-purposed glucose meter. Ebola and Lassa viruses are selected as relevant model systems because they are highly contagious with human-to-human transmission, high mortality rate and no vaccine/treatment available, thus having meaningful potential for new pandemic threats. To offer such a genuine sample-to-result quantitative POC solution, the DECIPHER value chain, from lab to market, will cover: (1) investigation of high-throughput manufacturing processes with (2) novel polymers, innovations in the fields of (3) microfluidics, (4) HMNs and (5) quantitative molecular bioassays, (6) DECIPHER patch analytical and clinical validation (both retrospective and prospective), as well as (7) AI-based models, (8) socio-economic/systems analysis and (9) life cycle assessment of DECIPHER patch. This true interdisciplinarity will be represented by hi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Functional ingredient from fermented vegetable waste streams to diminish the use of antibiotics in pig husbandry' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

PROVALOR is a highly innovative Dutch SME dedicated to the development of functional foods located in Hoofddorp (The Netherlands) and employing 15 people. Since 1998 we have been working in processing food wastes, particularly from vegetable remnants and obtaining functional ingredients for human consumption. Our strategy focuses in obtaining high-value ingredients, and we have a vast know-how in this field having released to the market several successful products such as foodfibers refined from vegetables, a meat substitute made exclusively from vegetables (first without soja), and juices refined from vegetable remnants.We have obtained a functional extract from fermented vegetable remnants through our ad-hoc exclusive methodology. When included as a functional ingredient  in pig feed in an amount of 0.02-0.05%, it promotes agglutination of hazardous bacteria in the pig’s gut, allowing them to get expelled with the faeces, minimising illnesses and reducing the necessity of the use of antibiotics.Antibiotics are a key tool against infectious bacterial diseases. The use of sub-therapeutic doses of antibiotics in food-animal feeds (growth promoters) has been a very common practice to prevent animals from diseases and to improve production performance in intensive animal husbandry, but this practice has been banned since 2006. This problem is a big issue, in the EU and worldwide, and great effort is being put to find viable alternatives. Actually there is a recently constituted Focus Group within EIP-AGRI, dedicated to “Reducing antibiotic use in pig farming”. They encourage to “further examine use of plant-based pig feed additives”. We have obtained an effective solution in this line, and considering an average content of 0,04% of PLANTIBIOTICS there is a potential market
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Dynamic river catchments in a Global Change context: assessing the present, preparing for the future' (SEDAHEAD) under Horizon Europe.

assistant: **Objectives**

In a Global Changing world sediment regime has emerged as a dominant actor in the modification of river catchments. The sediment regime refers to the sediment budget (amount, type and timing of sediment inputs, outputs and storage) of a river system as well as the way water and sediment interact to drive river conditions. Studies of sediment regime assessing the impact of Global Change are scarce and traditionally relies on deterministic approaches. However, at any given river catchment section, a complex imprint in the spatial-temporal distribution of sediment regime is observed. This imprint is caused by the temporal and spatial uneven production, storage activation and transport of sediments. Pure deterministic (and thus partial) solutions are not accounting for the natural variability of sediment regime and the inherent uncertainty due to Global Change. This means we are potentially missing half the story and that our attempts to forecast the current and future evolution of rivers areas, at both catchment- and reach-scale, may be more wrong than right. The tenet of this proposal is to describe and determine the Global Change impacts on sediment fluxes at all scales relevant for river catchment management by means of a modelling approach that can account for natural stochasticity and Global Change uncertainty. Three main and novel research questions have been identified and need to be addressed: (i) how (and how strongly) the headwaters control the main features of sediment regime; (ii) how to model sediment fluxes by means of a forecasting model capable to reproduce fluctuating (and thus realistic) sediment regime characteristics; and (iii) how to identify and incorporate the Global Change impacts on sediment regime modelling to assist in fostering a more robust riv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Evolving spaces: coastal landscapes of the Neolithic in the European Land Ends' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Coastal areas have been poles of population attraction since the early Prehistory. Today, in a context where sea-level rise is threatening significant amounts of territories across the European Atlantic Façade, understanding coastal landscapes has become a crucial topic. This concern operates at the local, national and international levels, as different organisations and research calls have stressed in the last few years. The role social sciences may play in building solutions to this problem is underestimated, and archaeological research must contribute to both the understanding of long-term coastal dynamics and the management strategies within these areas. In order to fulfil this double perspective the present project implements a coupled approach: one of basic research, one of heritage management. It is summarised in two basic objectives:1. Contributing, through the multidisciplinary and trans-regional analysis of the archaeological evidence, to the understanding of coastal landscape construction and dynamics from the Middle Neolithic to the Early Bronze Age in Western Europe (c. 4500-2200 BC).2. Assessing vulnerability of the coastal archaeological heritage and providing tools for its management.To reach the Objective 1 the megalithic architectures will be the primary reference source. Their immanence makes them highly appropriate to retrace the way landscapes have been connoted and have evolved around them. To reach the Objective 2 the research program will integrate and improve the research perspective on vulnerability assessment initiated by the candidate.Fieldwork research and Geographical Information Technologies will be the main methodologies in use.Three major regions have been chosen for this research, which correspond to some of the westernmost areas of Eur
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Unlocking a feather bioeconomy for keratin-based agricultural products' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Only in Europe 3,6 million tonnes of feathers are generated per year as waste of the poultry sector. Around 25% is used for animal feed or fertilisers while the rest is disposed in landfills or incinerated. Feathers contain nearly 90% of keratin, a valuable protein which can source for biodegradable materials, such as bioplastics for agriculture. However, to unlock the full potential of feathers as raw material for functional molecules, there are many technical, logistic and market hurdles to solve in the supply chain for the takeoff of profitable value chains and for the easy market uptake of keratin-based products. UNLOCK will design and demonstrate economically & environmentally sustainable value chains led by the primary sector, which will generate innovative bio-based functional products for agricultural applications: forest/seed trays, nonwoven geotextiles, mulch films and hydroponic foams. Keratin-based materials will outperform their fossil-based counter parts by providing additional functionalities during the product life span and environmental benefits at the end-of-life (controlled biodegradability, enrichment of organic nitrogen to soil and zero waste generation). UNLOCK will create 4 new bio-based value chains, 4 new agricultural consumer goods and at least 3 cross sector interconnections among the primary sector (poultry sector), the bioplastics industry and the agricultural sector, opening up new innovation-led market and job opportunities in the EU bioeconomy. UNLOCK conversion technologies will evolve from TRL5 to 7, demonstrating the full potential of keratin for circular bio-based plastics, through a multidisciplinary consortium of 15 partners (8 SMEs), supported by a strong stakeholder board. UNLOCK will enable the setup of 2 first-of-its-kind commer
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'All Condition Operations and Innovative Cockpit Infrastructure'.

assistant: **Concept**

ALICIA addresses the ACARE objective of increasing time efficiency within the future air transport system. The aim will be to develop a new and scalable cockpit application which can extend operations of aircraft in degraded conditions – “All Conditions Operations”. A key objective will be to deliver an extensible application that can be applied to many aircraft types.  This will necessarily entail a new cockpit infrastructure capable of delivering enhanced situation awareness to the crew whilst simultaneously reducing crew workload and improving overall aircraft safety.   All Conditions Operations, other challenging applications and the desire for reduced crew will mean that the crew station interface will be challenged beyond the reach of the current state-of-the-art. Accordingly, a radical rethink is required to manage the escalating complexity whilst simultaneously enhancing safety and controlling through life cost.  Thus, the next significant step in cockpit design will require a holistic integration of technologies allowing the crew to process and act on information concurrently and intuitively, using an optimum combination of their visual, tactile and audio senses.  In the concept envisaged, use will be made of precision navigation, synthetic vision, high integrity data bases, sensor and sensor data and image fusion, obstacle warning systems, taxi autopilots, touch screens, large area displays, voice/audio and multimodal input/output devices to deliver an All Conditions Operations application integrated within an enhanced crew interface. A major objective will be to deliver a common, and open standard interface which can manage existing core applications across all aircraft types whilst simultaneously supporting the needs of challenging new applications.  The ALI
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Leveraging the zombie-making strategies of Ophiocordyceps fungi to understand animal behaviour'.

assistant: **Innovation**

Reminiscent of zombies in pop culture, some parasites hijack host behaviours. Our understanding of this parasite strategy to improve transmission is minimal, despite its convergent evolution across major taxa. Functional genetics studies would advance our knowledge of the molecular underpinnings of “zombie behaviour”. Additionally, learning how behaviour can be altered would elucidate how “normal” phenotypes are maintained. However, most zombie-making parasites and their hosts are not classic model organisms, which complicates mechanistic interrogation.The so-called “zombie ants’ can be used to study parasite hijacking of animal behaviour in more detail. Zombie ants are infected by Ophiocordyceps fungi that cause summit disease. Infected ants ascend vegetation that they bite into as they die to ensure fungal spore dispersal. My lab developed fungal culturing techniques, infection methods and behavioural assays to detail infection-related changes in daily ant foraging, communication, and locomotion. Additionally, by integrating multi-omics tools, we identified candidate fungal products and ant host pathways that might underlie the behavioural changes observed. However, to move from correlation to causation these candidates need to be functionally tested.By leveraging my lab’s pioneering work and my training in molecular microbiology I aim to elucidate the molecular genetics underlying parasite hijacking of host behaviour. I propose to 1) adopt molecular genetics tools to characterise fungal products that induce altered host behavioural phenotypes, 2) use RNASeq and RNAi to investigate the affected ant pathways that give rise to those phenotypes, and 3) further establish involvement of these behavioural pathways through integration of the animal model Drosophila melanogas