RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Degradable on-demand conjugated polymer systems for transient bioelectronics' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The rapid growth of bioelectronics creates an urgent need for sustainable and degradable materials that can safely disappear after use, avoiding long-term persistence in the body or the environment. Organic electrochemical transistors (OECTs), with low-voltage operation, high ionic sensitivity, and good biocompatibility, are among the most powerful device platforms in bioelectronics. While degradation has been shown in selected p-type OECTs, progress on n-type counterparts is very limited. This gap is critical, as n-type OECTs are indispensable for detecting biologically relevant anions and enabling complementary circuits. To date, no reliable strategies exist to achieve controlled degradation of bioelectronics under physiologically relevant conditions—an essential requirement for biomedical and environmental applications.Conjugated polymers are the most important part of OECTs, combining electronic functionality with tunable chemical structures. Yet designing systems that deliver both high charge transport and predictable degradation remains highly challenging, since the structural features stabilizing electronic states often resist breakdown, whereas degradable motifs tend to compromise stability and conductivity.The DOPTE project addresses this challenge by creating degradable n-type conjugated polymers that unite electronic performance with controlled degradation. The central strategy is to integrate cleavable motifs into high-performance conjugated backbones, enabling degradation under physiological conditions or through near-infrared activation. The project will establish design guidelines for degradable bioelectronics, with the potential to reduce surgical retrieval in biomedical devices and support sustainable materials for next-generation bioelectronics. It wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Flexible and customised mass production of bicycle frames at lower costs'.

assistant: **Objectives**

Competition in bicycle production is killing Western European producers, due tothe low wages in Asia and Eastern Europe. The aim of this project is to developa production technology for mass production of bicycle frames to customerdemand, with increased flexibility compared to production today so Europeanproducers stay competitive. Therefore in this project it is proposed to: - increase the flexibility in frame geometry without lugs by using brazed joints having increased strength at wider gaps e.g. between 0 and 1 mm, - develop brazes suitable for brazing those joints at temperatures of around 800 - 900°C, a temperature range suitable for high tensile strength steel tubing, - developfaster tube preparation techniques like milling (high speed), shearing or lasercutting to machine varying angles at the butting end of the tube to be brazedto another, - develop flexible brazing fixtures to enable torch brazing ofmost frame geometries desired, The development of this technology will make theEuropean bicycle producers more competitive in the domestic and world markets. The expected savings for the European bicycle industry on an annual basis will be as high as 10.3 million ECU. Equal savings may be expected in the productionof furniture (chairs) and brazing of steel tubing for the production of heatexchangers.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Evaluation of the facilitation of umbilical cord blood transplant engraftment using ex vivo haematopoietic progenitor/stem cell expansion.' (1998-2002) under Fifth Framework.

assistant: **Objectives**

Umbilical cord blood cells collected at birth are increasingly used as a source of stem cells for transplants in patients with malignant and non-malignant diseases. Previous EUROCORD programs have identified prognostic factors for predicting the outcome. Delay of engraftment is the major problem particularly in adults. Using clinical data from EUROCORD Registry, we have identified several factors associated with engraftment including the cell dose and the role of HLA incompatibilities. In this new proposal, we plan to coordinate research on methods to improve clinical results of CBT assaying different strategies aiming to shorten engraftment time and to increase its probability by means of ex-vivo expansion of haematopoietic progenitor/stem cells from cord blood or multiple transplants as well as to better understand the mechanism of immune recovery. Clinical results will be evaluated through EUROCORD Registry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Multi-scale computational fluid dynamics modelling and optimisation of the state-of-the-art solid oxide fuel cells' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The presently proposed research project will be an integral part of the ongoing solid oxide fuel cell research at the Department of Energy Conversion and Storage in Technical University of Denmark (DTU Energy Conversion). DTU Energy Conversion is a world leader in research, development and commercialisation of solid oxide fuel cells.The third generation cell or metal-supported cell of DTU is currently at a more experimental stage. Here the anode support is replaced by a porous layer of ferritic stainless steel (approx. 78% iron and 22% chromium). The cell is constructed on top of a support consisting of iron and chromium. The anode is on the same metal powder as the support, but with a finer particle size. However due to the corrosion problems, other solutions are being sought, lanthanide doped strontium titanate (LST) being one of them. The advantages are a significant decrease in cost and an increased robustness in case of fuel supply failure or operating stop (redox and temperature cycles). At the same time the operating temperature is reduced to 550-650°C. In addition to the completely new support, all active components are being improved through characterisation, testing, and modelling.DTU Energy Conversion would greatly benefit from an additional researcher working on the crucial aspects of the modelling of the above novel SOFC development project. DTU Energy Conversion have identified a researcher with the ideal background to perform the multi-scale thermo-fluid and electrochemical modelling of the state-of-the-art planar SOFC using numerical modelling approaches (i.e. a combination of FEM and CFD) in three-dimensions and in the process receive training and enhance his experience in the multidisciplinary set of skills, including SOFC development and manufacture,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Investigating the Impact of the Innovation Union' under Horizon 2020.

assistant: **Concept**

Innovation has been placed at the heart of the Europe 2020 strategy aimed at facing major structural changes, the increase of global competition and the current crisis, and to tackle major societal challenges such as climate change, energy and resource scarcity, health and ageing. The Innovation Union has the main objective to strengthen the European innovative potential, and sets 13 general objectives and 34 specific (policy) commitments associated to the objectives, and aimed at stimulating innovation. The objective of this project is to deliver a system of assessment for the commitments. The approach starts from the evaluation of the state of achievement of the individual commitments, but puts crucial emphasis on their effects in the innovation system as a whole, as well as on the economy-wide effects of innovation. The basic idea is to retrace the entire chain of effects of the commitments, from their implementation to their final impact in terms of competitiveness, growth or employment. The specific tasks that project sets out to undertake to achieve this are:1) Data collection and identification of mechanisms;2) Developing theoretical and econometric models in order to estimate the impact of the commitments;3) Developing a conceptual model of the innovation system, leading to a reference tool on which the impact analysis of the commitments individually and as a whole will be based, and which will also play a role of interface between the assessments of the commitments impact and the macro sectoral econometric work.4) A quantitative analysis of the commitments by use of the NEMESIS model, which is an existing macro-structural econometric model, but which will be modified and extended for the tasks at hand;5) An ex-ante and ex-post policy assessment of the economic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Control of bacterial regrowth in water supply distribution systems in water short European and Mediterranean countries' under Fourth Framework.

assistant: **Concept**

The overall objective of this project is to develop a bacterial control tool, based on laboratory and field data, which can be used to predict bacterial regrowth problems in distribution systems, due to chemical and physical conditions including storage and infiltration.The main aim is to define the specific conditions under which bacterial regrowth can occur, with the objective of modelling water quality changes in distribution, thus enabling management of water supply operations to give significant improvement in water quality.Significant gastro-enteric health risks may occur if and when opportunistic pathogens such as Aeromonas, Pseudomonas, E.coli 0157/H7 and Yersinia are able to grow in distribution systems, so the project aims to establish the relationship between growth responses of heterotrophic plate counts, indicator organisms and these opportunistic pathogens.Using conditions in the 3 Mediterranean countries (water-short, warm climates) with intermittent supplies, household storage tanks, infiltration problems and higher endemic disease levels, should allow clearer understanding of the potential problems to be caused in Europe by global warming.Expected OutcomeThe main outcome of this project will be a greatly enhanced understanding of the combination of factors causing bacterial regrowth, leading to development of a model which can be used to predict and control the growth of bacteria, particularly in water-short European and Mediterranean climates. The model will be calibrated and validated against representative distribution systems in each country, and ultimately provide a tool which can be tailored to any distribution system.The key activities involve :* Definition of growth kinetics of representative coliforms, heterotrophic plate count organisms and op
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Spinoptical nanoantenna-assisted magnetic storage at few nanometers on femtosecond timescale'.

assistant: **Concept**

We will develop the conceptually new paradigm for ultra-dense and ultrafast magnetic storage that will exceed the current technology by two orders of magnitude in storage density (going from terabit/inch2 to tens of terabytes/inch2) and by about four orders of magnitude in operation speed (going from low GHz to THz for read/write). This will be achieved in an all-optical platform that allows deterministic, non-thermal, low-energy, ultrafast magnetization switching at few nanometers and potentially down to a molecular length-scale. The main building block of the envisioned memory unit in this new paradigm is the spinoptical nanoplasmonic antenna that concentrates pulsed polarized light at the nanometer length-scale and enables non-thermal spin-orbit mediated transfer of the light’s angular momentum (orbital and/or spin) to the nanoscale magnetic architectures. In this way fs-pulsed light, assisted by the plasmonic optical spin-selective antenna and the local electromagnetic field enhancement, allows for the precise control of the magnetic state of nanometer sized / molecular magnetic structures. The project aims to elucidate the fundamentals of the emergence and manipulation of light’s orbital and spin angular momenta to achieve non-thermal momentum-transfer-driven ultrafast switching process, to demonstrate its practical realization, and will map its suitability for future upscaling towards industrial implementation in devices.


**Keywords:** ultrafast magnetism,  spinoptics,  magnetoplasmonics,  molecular magnetism
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Sustainability assessment methods and tools to support decision-making in the process industries' (SAMT), addressing dissemination and exploitation.

assistant: **Impact**

Sustainability assessment methods are needed to support sustainable technology development and to evaluate the impacts of existing solutions, products and technologies. While there are aspects and indicators that are common to all process industries, sector specific tools are required to address the sector specific features in a fair and transparent way. At the moment, several tools, assessment methods and indicators exist, but they differ in their goal and scope and are intended for different kind of use within companies, by consumers or by authorities to support policy planning and evaluation. Additionally, different tools are focused for different levels of assessment: product, company, industry or society. Thus the problem is not so much the existence of proper tools but rather the lack of understanding and knowledge on how they should be applied and in which context. Furthermore, suitable tools for analysing resource and energy efficiency within the process industries and across the different sectors should be recognized.The aim of the SAMT project is to review and make recommendations about the most potential sustainability assessment methods for evaluating energy and resource efficiency in the process industry. The analysis will focus on the applicability of different methods in industrial settings, the ability of the methods to support decision-making towards sustainable solutions and the suitability of the tools for cross-sectoral analysis. SAMT will evaluate tools that cover either environmental, economic and social aspects, or a combination of these, and apply principles of life cycle thinking. The project will consider demands and make recommendations related to sectorial and cross-sectorial assessment in a wide spectrum of process industries: cement, metal,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Unlocking the methane cycling archives from Arctic lakes: a biological fingerprint'.

assistant: **Objectives**

Arctic landmasses and lakes release significant amounts of methane (CH4), a potent greenhouse gas that contributes to global climate change. Yet, the effect of rapid warming in the Arctic on the fate of CH4 emissions is poorly understood, particularly over decadal to millennial timescales. The recent advance of high-throughput sequencing and metabarcoding techniques to analyse ancient environmental DNA, or paleogenomics, from Arctic lake sediment has tremendously heightened analytical sensitivity and thus unlocked a wealth of new information on past ecosystems and their processes. I will combine this innovative approach to a robust paleoecological framework and multivariate analyses to study the drivers underpinning microbial assemblages involved in the cycling of CH4 during major periods of climate variability in Greenland since deglaciation. By using an important multi-site set of lake sediment cores spreading along major environmental gradients and collected by the Anthropocene-Quaternary Research Group, I will upscale the study from catchment to region and from the present Anthropocene (~last 150 years) to the early deglaciation of the Holocene (~11,700 years ago). This dataset will also enable me to control for the different catchment-specific processes that may have influenced microbial abundance, diversity and function in the past, and isolate the influence of climate on their ecology. This interdisciplinary approach will be supported by the analysis of additional paleoecological proxies for other important components of the carbon cycle in Arctic watersheds via collaborations with Canadian and Australian laboratories. While acquiring new expertise in cutting-edge paleogenomics and microbial ecology in world-leading research facilities at the Centre for GeoGeneti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Understanding the balance between functional and deleterious interactions of alpha-synuclein with lipid bilayers' to be submitted under Horizon 2020.

assistant: **Abstract**

Proteins are among the most essential molecules of life. In order to fulfil their native function(s) they need to adopt a well-defined three-dimensional structure. However, under some circumstances, proteins can misfold and/or form toxic amyloid structures, which are the hallmark of a range of diseases including type 2 diabetes and neurodegenerative diseases. In particular, the small pre-synaptic protein, alpha-synuclein (AS), whose aggregation is the hallmark of Parkinson’s disease, can adopt in vivo and in vitro an intrinsically disordered conformation in solution and an alpha helical state when bound to membranes; the equilibrium between these two conformations has been shown to be important for its proposed native function, e.g. synaptic plasticity, and to modulate its kinetics of fibril formation. Here, I propose to investigate the physiological factors responsible for the switch between functional and deleterious interactions between membrane bilayers and AS due to ageing or disease using an innovative combination of biological,  structural, thermodynamic and kinetic studies. In particular, I propose to use both synthetic lipid model systems and isolated synaptic vesicles to study the effect of ageing and the presence of lipids associated with Parkinson’s disease pathology on the nature of the interaction between AS and lipid bilayers. The synaptic vesicles will be isolated from the brain of mice at different ageing stages, as well as from mice carrying gene modifications or knock out related to PD. The interaction between AS and the vesicles will be studied using a range of biophysical techniques including circular dichroism, fluorescence and nuclear magnetic resonance spectroscopy, Atomic Force and Electron Microscopy.The aim of this study is to establish a thor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Monocyte-to-Macrophage Trajectories After Lung Injury: Spatio-temporal investigation, molecular regulation & functional implications for lung regeneration and immunity' (MoMacTrajectALI).

assistant: **Concept**

The lung is particularly exposed to airborne and blood-borne insults. The mechanisms underlying lung tissue repair are therefore of fundamental biological importance and have critical implications for the prevention life-threatening inflammatory and tissue-damaging responses. Lung-resident tissue macrophages and inflammatory monocyte-derived macrophages (InfMoMac) are key players in the maintenance of homeostasis, repair responses and disease pathogenesis. Yet, to date, the complexity of lung macrophage responses after injury is far from being resolved. Here, we propose to explore InfMoMac trajectories and functional diversity in an unprecedented manner. To this end, we will use mouse models of infectious and non-infectious lung injury combined with single cell and spatial analyses, robust fate-mapping models and gene targeting approaches to investigate the spatio-temporal regulation, the subtissular niches, the intrinsic molecular programs and the extrinsic stress-, inflammation- and niche-related signals imprinting the identities and functions of InfMoMac subpopulations, and the functional consequences of the maintenance of InfMoMac for lung immunity to a subsequent challenge. Finally, we will investigate the interactions of InfMoMac with niche cells in humans by analyzing the InfMoMac landscape in human injured lungs and by studying a novel human embryonic stem cell-derived lung organoid model in co-culture with monocyte-derived cells. Based on robust preliminary data, sophisticated models and cutting-edge technologies, this ambitious project will increase our understanding of the basic mechanisms underlying the fine-tuning of InfMoMac trajectories in response to lung injuries and will thus provide robust foundations to manipulate their fate in medically relevant con