RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'The development of a hand held friction stir spot welding gun for automotive vehicle body repair', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

Aluminium usage in automotive vehicle bodies within Europe is increasing as well as the use of high strength steels. This increase is predominantly due to demands placed on manufacturers to reduce fuel consumption, reduce exhaust emissions and meet recyclability targets. It is expected that the use of aluminium in cars and light vehicles will increase by 7% per year up to 50% by 2010 and that production volumes of high aluminium content vehicles is expected to reach around 30% of the total production volume in the EU in 2010. Common methods for joining aluminium panels in production include; resistance spot welding, fusion welding and the use of rivets, clinching, adhesives etc. There is a problem however that exists in the vehicle body repair sector, which is dominated by SMEs.This is associated with the repair of aluminium- bodied vehicles and also the repair of high strength steel body panels. Current joining methods can be very expensive, for example the Audi A8 is quoted as being 40% more expensive to insure than its steel bodied equivalents, for this reason. There is an opportunity for the SME partners to develop technology in the areas of aluminium vehicle body and high strength steel vehicle body repair that will be used in SME vehicle repair body shops.Friction stir spot welding is emerging as a very attractive joining method for aluminium vehicle bodies, with potential also for high strength steel. It is a variant of the friction stir welding process and involves plunging a rotating tool into a lap joint, forging a spot weld and then retracting the tool. There are significant advantages of FSSW over more established joining methods - less power consumption, produces an excellent joint, is extremely fast when compared with mechanical methods and produces a homo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Identifying network control elements in breast cancer oncogenic transformation via whole transcriptome analysis' (CONTROLNETONCTRANS) under Seventh Framework.

assistant: **Objectives**

Understanding tumorogenesis is a prerequisite to designing rational cancer therapies. Tumorogenesis, and systems biology generally, requires its own set of tools for dealing with masses of high-throughput data. I have demonstrated such abilities over the years, both in the task of single handedly integrating disparate data into the microenvironment of the mammalian thymus as well as in the integration of genome-wide data into biologic understanding through concepts of network and signalling pathways. I approach systems biology with training/research in mathematics, physics, computer science, immunology, and tumor and stem-cell biology. I recently devised a metric for characterizing cancer cells based gene pathways as the basic unit of measurement; the pathway metric was able to detect a cancer signature with 98% success, irrespective of tissue origin, grades, stages and patient clinical data. The metric also predicted patient survival. Representing a sample through its pathway profile served as a powerful tool for classification, but it also enabled process reduction to discover essential molecular mechanisms.I am now on a tenure-track process of establishing my own lab. The technological revolution in molecular biology makes it possible to follow the process of oncogenic transformation at a whole transcriptome scope, in high resolution and at relatively low cost, through RNA sequencing using next generation, massive parallel, sequencing technology. Previously, I showed how genome-wide measurements can be integrated into scientific understating of stem-cell differentiation. I will now apply this whole-transcriptome approach to study controlled oncogenic transformation in vitro. The ultimate aim is to uncover specific processes that are amenable to specific, rational dru
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The development and evolution of the mesoderm in basal bilaterian acoel worms' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Understanding the evolution of the diversity of animal forms is one of the major tasks in biology. The use of molecular biology led to a better understanding of how evolutionary changes in the development can result in changes in the body plan. Modifications of the wiring between genes caused the adoption and co-option of gene regulatory networks that shape the morphology of the adult during the development. To get a better picture of how these changes led to evolutionary novelties one has to investigate animals that are representatives of key-nodes in the animal tree of life. A fundamental innovation of complex animals is the third germ layer – the mesoderm, that is characteristic for all bilateral symmetric animals that include flies, worms and humans. The mesoderm gives rise to important organ systems such as skeletal elements, musculature, heart and kidneys. Recent insights gained from studies of the development of cnidarians – the most closely related group of the bilaterians – suggest, that the mesoderm evolved from the internal germ layer the endoderm. Comparative studies between animals can reveal how the gene regulatory network that specifies the endoderm of cnidarians has been changed so that it gives rise to a novel germ layer, the mesoderm. The ideal organisms to investigate for answering this question are the simple acoel worms, which form the earliest evolutionary branch of all bilaterian animals. The proposed research project has the aim to investigate the gene regulatory network that specifies the endoderm and mesoderm of the acoel species Convolutriloba longifissura using modern molecular tools. By describing the detailed temporal and spatial expression of key regulatory genes and a following functional analysis important information will be gained that
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Impact of invasive alien true bug species in native tropich webs' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Insects can be accidentally introduced into non-native ecosystems by humans, or expand their geographical range toward the poles as a consequence of global warming. As they invade new environments, exotic species interact with local species, modifying the structure of local food webs. New associations arising from with biological invasions can impact the strength of existing links with effects cascading through trophic levels. When invasive species are herbivores that can attack economically important crops, they can cause serious economic losses. For example, recent invasion of the brown marmorated stink bug (BMSB) (Halyomorpha halys) in Europe and North America has the potential to interfere with local trophic webs and poses a serious threat to several agro-ecosystems. In this project, we will adopt a multidisciplinary approach to study the ecological consequences of BMSB invasions. In particular, we will focus on the effect of alien herbivore invasion on local natural enemies using the following work packages: 1) the impact of exotic herbivores on infochemical communication between plants, herbivores and natural enemies; 2) Learned responses of parasitoids to infochemical evolutionary traps in a climate change context; 3) Contest behaviour of local egg parasitoids for possession of co-evolved and non-coevolved hosts; 4) Patch time allocation of local egg parasitoids after alien herbivore invasion: behavioural and modelling approaches; 5) Molecular aspects of indirect plant defences against invasive and local species 6) Genetic structure of invasive alien herbivores across Europe and North AmericaThe proposed research will be of great relevance for the RISE call as it will be an unparalleled opportunity for complementary European and Canadian research groups to join f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Unipolar Semiconductor Lasers' under Fourth Framework.

assistant: **Concept**

The primary objective of this project is to develop a new class of unipolar mid ir (3.5 to 15 m) semiconductor lasers (Quantum Cascade Lasers) for sensing applications, operating in pulsed mode at room temperature. These devices are based on intersubband transitions (ISBT) and as such their emission wavelength does not depend upon the gap of the constituent materials but is essentially determined by quantum confinement. Therefore, conventional III-V material can be used to design and fabricate mid ir lasers that would be ordinarily based on narrow-gap semiconductors. In addition these lasers will be provided with shallow gratings for wavelength selection (DFB technology) and finally mounted on Peltier elements for temperature stabilisation and wavelength tuning. The final result of the project will consist of a prototype sensing system characterised by high sensitivity, compactness, low cost and maintenance which will be easily accepted to different installations following specific industrial requirements. The core of this project is not an incremental work on existing technology but is the opening and development of a new semiconductor device technology to aid the European industries and know-how to expand against the US hegemony in this field. It is in this pioneering spirit that this proposal is submitted for approval to BRITE-EURAM BASIC RESEARCH. Laser spectroscopy is the ultimate tool to accurately measure narrow absorption lines in the mid-ir spectral region (3 - 15 1lm).Today the only commercially available sources suitable for such applications are semiconductor lead salt lasers, which operate only at cryogenic temperature. All other sources are either too bulky and costly (OPO and FEL) or limited to fixed wavelengths (gas lasers). Marketing research has identi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'The role of interpersonal neural SYNchrony during verbal CONversations: Correlation, Causation and Personalization' in the context of a Horizon Europe call.

assistant: **Objectives**

Verbal conversations are a hallmark of human social interaction and are supported by various socio-cognitive processes promoting specific conversation patterns. For instance, more engaging conversations are marked by how often and quickly participants switch turns speaking (turn-taking). Similarly, an engaging conversation is also marked by the interlocutors converging towards a common phonetic space (phonetic convergence). One of the neural mechanisms supporting these conversation patterns is proposed to be interpersonal neural synchrony (INS), the coupling of brain oscillations between two interlocutors. However, only a few studies truly tested the role of INS during free-flowing conversations. These studies have some limitations as they were either conducted in a non-ecologically valid context or the evidence was purely correlational. In addition, important inter-dyadic differences were neglected. The present project – SYNCON – aims to overcome these limitations by combining EEG hyperscanning with multi-person brain stimulation (tACS) and personalized neuroscience. I will first measure the correlation between INS and mutually engaged conversations marked by enhanced turn-taking and phonetic convergence. The measurement will yield a dyad-specific INS profile, considering properties such as frequency, phase, and topography. Utilizing a longitudinal design, these profiles will allow me – in a second experiment – to exogenously induce INS between interlocutors and, in turn, promote mutually engaged conversations (i.e., increased turn-taking and phonetic convergence). Understanding the causal role of INS in conversations will have groundbreaking applications for facilitating interpersonal communication across therapeutical and educational contexts. Accordingly, this proje
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Microbial organo-sulfur desulfurization in the mycorrhizosphere' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Sulfur is a macro-nutrient that is essential for growth and plants need 1-5mg sulfur per gram biomass. However, most of the sulfur in soils is bound to organic molecules (organo-S) as sulfate esters and sulfonates. While plants are almost entirely dependent on sulfate, many bacteria and fungi are capable to mobilize sulfur from sulfate esters, and specific bacterial guilds can utilize sulfonates as a sulfur source.Most plants receive nutrients not directly from the soil but largely through fungal networks. Mycorrhizal fungi are living in symbiosis with the plant host where the plant supplies the fungus with sugars and the fungus supplies the plant host with soil nutrients. Up to now, it is unclear where the soil sulfur comes from that mycorrhizal fungi supply to the plants. This is of special interest in agricultural systems where a sustainable sulfur supply through arbuscular mycorrhizas could replace inorganic fertilizer applications. The hypothesis of this fellowship is that sulfate esters and sulfonates are mobilised by certain fungi and bacteria in the mycorrhizosphere and arbuscular mycorrhiza transport the mobilised form to the plant host.The aim of this study is to i) determine the direct and indirect involvement of arbuscular mycorrhizal fungi, saprophytic fungi and bacteria in organo-S mobilization in the mycorrhizosphere and ii) to identify and quantify the activity of organo-S desulfurizing microorganisms.Fungi and bacteria will be isolated from mycorrhizal pastures. Monoxenic microcosms with Agrostis as host plant, Glomus as mycorrhizal symbiont and selected organo-S mobilizing microbes will be set up to quantify the flow of organically bound stable isotope S through this system. In addition, non-sterile mesocosm systems will be set up to follow the flow of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Connected Open Identifiers for Discovery, Access and Use of Research Resources' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The goal of the FREYA consortium is to iteratively extend a robust environment for Persistent Identifiers (PIDs) into a core component of European and global research e-infrastructures. The resulting FREYA services will cover a wide range of resources in the research and innovation landscape and enhance the links between them so that they can be exploited in many disciplines and research processes. This will provide an essential building block of the European Open Science Cloud (EOSC). Moreover, the FREYA project will establish an open, sustainable, and trusted framework for collaborative self-governance of PIDs and services built on them.FREYA capitalises on the successes of the THOR project and will build on the core services of the existing trusted PID systems of the project partners, developing them in the context of established community-based services and more widely through the EOSC. The FREYA e-infrastructure components will be built on technologies and services that are already well proven. New services, and new PID types, will be introduced and moved up the scale of Technology Readiness Levels, so that the emerging e-infrastructure services are prototyped and positioned for evolution beyond the end of the FREYA project.The vision of FREYA is built on three key ideas: the PID Graph, PID Forum and PID Commons. The PID Graph connects and integrates PID systems to create an information map of relationships across PIDs that provides a basis for new services. The PID Forum is a stakeholder community, whose members collectively oversee the development and deployment of new PID types; it will be strongly linked to the Research Data Alliance (RDA). The sustainability of the PID infrastructure resulting from FREYA beyond the lifetime of the project itself is the concern
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Priming for L-dopa-induced dyskinesia and neurotransmitter receptor trafficking dysregulation in parkinsonism' (PRIMLID).

assistant: **Innovation**

L-dopa-induced dyskinesia (LID) severely limits the usability of L-dopa in Parkinson’s disease (PD) patients and a treatment is needed to improve their quality of life. The project aims at elucidating the “priming” phenomenon in PD, i.e. the unchangeable modification of brain response to dopamine (DA), that leads to the development of LID. We will investigate the role of neurotransmitter receptor homologous desensitization and its consequences upon main intracellular signalling cascades, i.e. the canonical pathway and the mitogen-activated protein kinase cascade (MAPK) through activation of different scaffolds, in various experimental models: namely an in vitro nigrostriatal slice model, the rat model of abnormal involuntary movements and the non-human primate model of LID. The program aims at elucidating the priming pathophysiology onto which we would then develop proof-of-concepts treatment approaches using TAT-peptides specific of the different docking domains of ERK1/2 for discriminating between the cytosolic and nuclear effects of this cascade. SA1: To be continued throughout the project for producing the in vitro parasagittal nigrostriatal slice culture model and the rat experimental model. Tissus from non-human primates are already available. SA 2: Real-time study of DA and mGlu receptor trafficking using quantum dot imaging on primary striatal cultures. SA3: Time course of subcellular trafficking of DA and mGluR receptors, of the protein machinery of homologous desensitization (GRK/arrestin) in DA-depleted cultures/brains that have never been in contact with a dopamimetic (immunohistochemistry – light, deconvolution of fluorescence, electron microscopy – subcellular fractionation). SA5: Behavioral impact of specific blockade of cytosolic vs. nuclear targets of E
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Immigration et asile en Europe - Bilan de Maastricht et perspectives d'Amsterdam' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

La conférence vise à étudier l'impact des traités de Maastricht et d'Amsterdam sur l'immigration et l'asile au niveau européen. L'objet est double:1) Faire un bilan critique des actes adoptés et des actions entreprises sur la base du traité de Maastricht;2) Evaluer de manière prospective les actes et actions pouvant être adoptés par la Communauté européenne à partir des dispositions nouvelles du traité d'Amsterdam.Organiser une telle conférence présente un intérêt scientifique certain parce que le sujet est abordé d'une manière peu courante d'un point de vue matériel (le contenu des normes) et non pas institutionnel qui a jusqu'ici été le plus fréquemment retenu.ftp://ftp.cordis.lu/pub/improving/docs/HPCF-1999-00073-1.pdf