RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'How the human brain combines the certainty of prior expectations and the clarity of sensory input during speech perception' (EXPECTBRAIN) under Horizon 2020.

assistant: **Objectives**

A fundamental question in the study of human perception concerns how we combine new sensory information with prior knowledge. Different underlying neural mechanisms have been proposed for how perceptual priors are combined with sensory input depending on their respective certainty to generate a subjective experience. Predictive Coding models suggest that neuronal populations compare (bottom-up) input from the sensory organs against (top-down) predictions so that only the unexpected part of the input is processed. Alternative models (e.g., Sharpening) propose that perceptual representations of the expected sensory input are enhanced while unexpected sensory input is suppressed. The objective of this proposal is to close this controversial research gap by testing 1) how top-down and bottom-up influences on perception depend on their respective certainty, i.e., the confidence in prior predictions and the clarity of sensory evidence, and 2) whether and how this mechanism is related to inter-individual differences during perception. To achieve this I will test multiple neuroimaging techniques (fMRI and EEG) against computational simulations of the two models. I will use state-of-the-art brain-activity pattern analysis to decode brain responses to individual words during perception of degraded speech. The innovative approach of combined pattern-information analysis techniques will allow unprecedented access to decode how prior information changes the representation of sensory information. The results of this project will have important implications for several clinical areas, e.g., the treatment of hearing impairments and neuropsychiatric conditions that are accompanied by aberrant perceptual experiences such as autism or schizophrenia. By strengthening my portfolio of resear
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Ultra-fast control of THz plasmon polariton resonances'.

assistant: **Objectives**

Active control of the optical properties of materials represents one of the most fundamental aspects of photonics. It is crucial to deepen our understanding on light-matter interactions, and for the development of novel technologies. Of special importance is the interaction of light with metal surfaces, leading to surface plasmon polaritons (SPPs). SPPs can give rise to giant local field enhancements in subwavelength volumes. Thanks to recent developments in plasmonics, electromagnetic fields can nowadays be controlled in subwavelength volumes and on ultra-fast time scales. However, research has been limited to optical and near-IR frequencies. The lack of studies at lower frequencies originates from the weak confinement of SPPs at these frequencies. Our objective is to overcome these limitations, demonstrating for the first time ultra-fast control in subwavelength dimensions of plasmonic resonances at THz frequencies. In particular, we plan to control localized surface plasmon polaritons (LSPPs), arising from the coherent oscillation of charges in particles. For this purpose, we will fabricate semiconductor particles supporting LSPPs, which will be controlled optically at very low fluences. We will show that the spatial distribution of giant field enhancements can be tuned with unprecedented accuracy by demonstrating its optical switching by several orders of magnitude. Moreover, we will study for the first time the active coupling of plasmonic resonances in periodic arrays of semiconductor particles. These arrays will constitute the plasmonic analogue to phased array antennas. The project will open new horizons in fundamental research, as well as in applications such as THz modulators and sensors.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Unravelling ultrafine particulate matter and micro nano plastic's mechanisms of impact on fetal health' to be submitted under Horizon Europe.

assistant: **Abstract**

The UPRISE project aims to unravel the complex mechanisms by which air pollution, in particular ultrafine particles (UFPs) and micro-nanoplastics (MNPs), disrupt normal fetal development leading to an increased risk of adverse birth outcomes (ABOs), including preterm birth, increasing the risk of premature children to develop a range of non-communicable diseases (NCDs) in adulthood. UPRISE will develop exposure databases and assessment models for these emerging pollutants in different exposure scenarios to improve our understanding of their sources, concentrations and dispersion patterns. UPRISE will include a clinical study with pregnant participants exposed to different levels of UFPs and MNPs pollution to analyse possible modes of action leading to ABO based on transcriptomic, epigenetic or mitochondrial mutation analysis and subsequently identify possible key events, including molecular initiating events. As a result, causal models supported by weight-of-evidence analysis will be developed to demonstrate the link between contaminant uptake and events triggering the ABO of interest. To facilitate the dissemination of results and their application in policy-making, UPRISE will develop user-friendly tools for reporting and sharing data, with the aim of facilitating the integration of scientific evidence into the updating of European and national air quality standards. By advancing in the quantification of the public health impact of prenatal air pollution exposure and providing guidelines and decision support tools for policy makers, the project will contribute to reducing the burden of NCDs associated with preterm birth and other ABOs.


**Keywords:** Birth adverse outcomes, air pollution, ultrafine particles, micronano plastics, urban environment
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Production and delivery of antibody fragments against gastrointestinal pathogens by lactobacilli' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Enteric infections remain a major cause of morbidity and mortality globally, accounting for an estimated 2 millions deaths each year. Effective preventive and therapeutic interventions are not yet available for many etiological agents of diarrheal diseases. Furthermore, even where vaccines are available, the lag time needed to induce an immune response can be critical in epidemic situations.   We have developed a model system in which Lactobacillus, a GRAS microorganism, can be transformed with antibody fragment encoding vectors. This allows the production of functional single-chain antibodies against mucosal pathogens in situ. These antibody fragments retain their biological properties in vivo and may mitigate or prevent disease.   The aim of this project is to develop an effective treatment against rotavirus and Clostridium difficile based on lactobacilli producing VHH and scFv antibody fragments. As a proof of principle, a lead VHH fragment against rotavirus will be tested in a human clinical trial in India. In parallel, we will generate, select and express scFv and VHH fragments against the gastrointestinal pathogens rotavirus and C. difficile in lactobacilli. The modified bacteria will be tested for their protective capacity in animal models. The genes encoding the antibody fragments will further be cloned using food grade and biologically contained expression systems and these lactobacilli will be tested for safety in a human clinical trial.   Our approach, which falls into the priority ""Innovative approaches and interventions"" and the work program ""Development and production of new generation antibodies"" represents a novel system for the induction of passive immunity that can be rapidly applied to populations at risk (for example through the drinking water, r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Controlling excitability in developing neurons: from synapses to the axon initial segment', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

A critical question in neuroscience is to understand how neurons wire up to form a functional network. During the wiring of the brain it is important to establish mechanisms that act as safeguards to control and stabilize neuronal excitability in the face of large, chronic changes in neuronal or network activity. This is especially true for developing systems that undergo rapid and large scale forms of plasticity, which could easily lead to large imbalances in activity. If left unchecked, they could lead the network to its extremes: a complete loss of signal or epileptic-like activity. For this reason neurons employ different strategies to maintain their excitability within reasonable bounds. This proposal will focus on two crucial sites for neuronal information processing and integration: the synapse and the axon initial segment (AIS). Both sites undergo important structural and functional rearrangements in response to chronic activity changes, thus controlling the input-output function of a neuron and allowing the network to function efficiently. This proposal will explore novel forms of plasticity that occur during development and which are key to establishing a functional network. They range from understanding the role of activity during synapse formation to how pre- and postsynaptic structure and function become matched during development. Finally, it tackles a novel form of plasticity that lies downstream of synaptic inputs and is responsible for setting the threshold of action potential firing: the axon initial segment. Here, chronic changes in network activity results in a physical relocation of the AIS along the axon, which in turn alters the excitability of the neuron. This proposal will focus on the central issue of how a neuron alters both its input (synapse
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'ERMES: An Earth obseRvation Model based RicE information Service'.

assistant: **Concept**

ERMES (An Earth obseRvation Model based RicE information Service) aims to develop a prototype of downstream service dedicated to rice sector based on assimilation of EO and in situ data within crop yield modelling. The objective of this service, targeted to European needs, is to: a) contribute to the regional authorities in the implementation of agro-environmental policies;b) support farming activities for sustainable management practices;c) provide independent reliable information to the agro-business sector.The long term goal is to extend and adapt the service to Asian and African markets, in order to boost European competitiveness and contribute to a sustainable development.On the base of previous experience of the consortium partners in rice mapping and monitoring with SAR/optical data, biophysical parameters retrieval, rice growth and development modelling and meteo variables estimation, two services are foreseen: Regional Rice Service (RRS) to provide to public authorities a customized agro-monitoring system devoted to regional yield estimates and risk alarming. Digital maps and bulletin will be disseminated via web through INSPIRE compliant geo-portal;Local Rice Service (LRS) to provide to the private sector (farmers and agro-services and insurance companies) high level information on yield variability, risk alert and crop damage assessment at farm scale. Advanced smart technologies will be used to receive in-situ observations from the user, to be ingested in crop model, and to disseminate customised information to them.The maturity of GMES/Copernicus core products and the advent of Sentinel data represent the right framework to develop specific EO based added value products for agriculture sector. In particular the complementary information of Sentinel SAR and O
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'DOUBLE GLAZING PV SOLAR FACADE FOR BUNDESVERBAND FLACHGLAS' (1994-1998).

assistant: **Innovation**

Since the area required for photovoltaic plants is relatively high, an access to existing adequate areas in the densely populated European regions is needed. The combination of the OPTISOL PV module technology with the newest state-of-the-art of special insulating glasses into a double glazing PV unit will result in a solar facade technology with optimized passive indoor climatization features. The basic aim of this project is to set new standards in :- photovoltaic facade and building integrations- an optimization of the facade's passive indoor climate regulation ability using- newest glass insulation technologies- and thus an improvement of the buildings energy balance- architectural aesthetics.The PV generator is working as expected. Since the commissioning is not yet terminated, measured results are not yet documented.The new headquarter building of BUNDESVERBAND consists of a large glass facade building segment which represents more than 35% of the overall building. The facade is divided into 3 different architectural facade concepts comprising : - an inclined infront building part ( wintergarden)- a vertical facade front- an overhead glass roofingThere are 18 different module types including, with a total number of 182 modules covering an area of 400 m². The installed solar power is 28.5 kWP. The polycristalline cells with the dimension 125 by 125 mm are fabricated by Eurosolare. The PV plant is connected to the grid by means of an master/slave inverter configuration consisting of four 5 kW inverter units from SMA Regeltechnik.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Interlayer exciton interactions and their many-body physics' (IXIXions) under Horizon Europe.

assistant: **Objectives**

Monolayer transition metal dichalcogenides (TMDs) exhibit exceptional properties to study many-body physics with direct optical control through their tightly-bound excitons and enhanced Coulomb interactions. Even more versatile physics emerge in heterobilayers of TMDs, which host long-lived dipolar interlayer excitons (IXs), with promising potential for quantum simulation experiments and realizing a plethora of correlated phases. In recent years, TMD heterobilayers have been at the center of many-body physics where effects such as the formation of a Wigner crystal, the demonstration of Hubbard model quantum simulation and the realization of Bose-Einstein condensates are just a few examples. However, deterministic control of single IXs and therefore interactions among individual IXs has not been shown. For MSCA project, I propose to study many-body physics of IXs, starting from the individual IX level and then progressing to small and well controlled IX populations. To do so I will use nanoscale patterned graphene electrical gates to trap and manipulate them. This top-down approach is scalable and flexible, allowing for the creation of arbitrary trap potentials and geometries. The scope of this two-year project is to use this technique to fundamentally study the exciton-exciton interactions that are at the basis of the exciting physics that arises from these new materials. However, the scientific potential of a method that can site-control IXs does not end here, this technique could form the foundation for quantum-simulation, demonstration of Hubbard model physics and exploring new quantum phases.


**Keywords:** 2D-materials, transition metal dichalcogenides, interlayer excitons, quantum confinement, coulomb interaction, exchange interaction
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Policy Learning of Motor Skills for Humanoid Robots'.

assistant: **Concept**

The goal of SKILLS4ROBOTS is to develop a autonomous skill learning system that enables humanoid robots to acquire and improve a rich set of motor skills. This robot skill learning system will allow scaling of motor abilities up to fully anthropomorphic robots while overcoming the current limitations of skill learning systems to only few degrees of freedom. To achieve this goal, it will decompose complex motor skills into simpler elemental movements – called movement primitives – that serve as building blocks for the higher-level movement strategy and the resulting architecture will be able to address arbitrary, highly complex tasks – up to robot table tennis for a humanoid robot. Learned primitives will be superimposed, sequenced and blended. Four recent breakthroughs in the PI’s research will make this project possible due to successes on the representation of the parametric probabilistic representations of the elementary movements, on probabilistic imitation learning, on relative entropy policy search-based reinforcement learning and on the modular organization of the representation. These breakthroughs will allow create a general, autonomous skill learning system that can learn many different skills in the exact same framework without changing a single line of programmed code. To accomplish this goal, our skill learning system will autonomously extract the necessary movement primitives out of observed trajectories, learn to generalize these primitives to different situations and select, sequence or combine them such that complex behavior can be synthesized out of the primitive building blocks. We will evaluate our autonomous learning framework on a real humanoid robot platform with 60 degrees of freedom and show that it can learn a large variety of new skills.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Immunopathogenesis of respiratory syncytial virus infections in calves, mice, non-human primates, and humans : development of second generation subunit vaccines.' (IMPRESSUVAC) targeting Fifth Framework.

assistant: **Abstract**

Infections with human and bovine RSV are major causes of severe respiratory disease. RSV vaccine development has been hampered by immuno pathological phenomena occurring during vaccine trials in infants in the 1960s with formalin-inactivated virus preparations (FI-RSV). Vaccination /challenge studies in rodents provided insight in possible underlying immunological mechanisms. Predisposition for enhanced pathology has also been demonstrated in calves and monkeys, but immune mechanistic studies have not been carried out. Here, we propose to identify immunological correlates of enhanced disease after FI-RSV vaccination in calves and mice (bRSV) and macaques (hRSV). Subsequently, we will evaluate three different non-replicating RSV vaccine candidates in these models, and in an established hRSV mouse model. In addition, we will study the RSV-specific immune response to one of these candidates in ongoing phase I/II human trials.