RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Extracting products of high added value from vegetal species of the mediterranean basin using non-organic solvents' under Fifth Framework.

assistant: **Concept**

The extraction of products derived from vegetal species used in the food, pharmaceutical, and cosmetic industries are heavily dependent on the use of organic solvents such as hexane and dichloromethane. The use of these solvents at high temperature entails some limitation in the purity and quality of the extracted products and is not without consequence for human health and the environment. The alternative technology proposed would obtain high quality natural products using non - toxic solvents and is based on the capacity of supercritical fluids, and mainly CO2 to dissolve natural products in a very selective form based on precise combination of pressure and temperature. The development of this technology coupled with the careful choice of the raw materials used (organically grow plants) would result in the production of extracts with minimal alterations in the colours, scent and flavour and free form toxic residues to the benefit of consumers and the mentioned industries.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Structural and functional insights into the assembly of respiratory complexes by a novel putative chaperone'.

assistant: **Innovation**

Cellular respiratory complexes play a central role in the production of ATP, the universal energy source of life. Defects in their activity are linked to neurodegenerative diseases in humans and antibiotics resistance in bacteria. Despite their capital importance, the assembly mechanisms of respiratory complexes remain highly unexplored.This research project aims to investigate how the assembly of the major bacterial respiratory Complex I is assisted by a multi protein system involved in enterobacterial stress response. The host team recently solved the structures of two components of this system with cryo-electron microscopy (cryoEM) and X-ray crystallography, and showed that they form a huge cage-like assembly reminiscent of the GroEL-ES chaperone. Importantly, the latest scientific literature reported physical interactions between this macromolecular assembly and specific subunits of E. coli respiratory complexes.To elucidate the functional role of this enigmatic machine in the assembly of Complex I, I will employ a highly integrated approach situated at the front line of molecular structural biology. A wide range of biophysical methods will be used to dissect the affinity and kinetics of individual interactions between components of this multi protein system and subunits of Complex I. I will examine the overall architecture of the formed complexes with negative stain electron microscopy and small-angle X-Ray/Neutron scattering, while atomic resolution insights of the complexes will be provided by high resolution single particle cryoEM and X-ray crystallography.The structures and functional insights obtained in the proposed project will improve our general understanding of coordination between protein folding and assembly of respiratory complexes, and bring novel ins
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Simulation and Theory of Astrochemical Reactions on Surfaces'.

assistant: **Innovation**

Over 300 molecules have been identified in interstellar space, ranging from simple H2 to complex organic molecules such as ethanolamine. In the extreme conditions of interstellar space, gas-phase reactions alone cannot explain their formation, and ice-covered dust particles are believed to play a crucial role. However, little is known about the precise mechanisms of interaction between interstellar gas and icy dust particles, or how these ice surfaces might ""catalyze"" the necessary chemical reactions. In particular, the effect of charge remains poorly understood. The STARS project aims to establish a new framework to investigate these interactions on both neutral and charged ice particles using state-of-the-art computational techniques. I will construct representative ice structures, calculate binding energies of astrochemically relevant molecules, and compute free energy profiles and rate coefficients for a paradigmatic set of reactions. In collaboration with leading experts in the field, I will also assess the impact of these interactions on resulting gas-phase abundances, enabling accurate benchmarking against experimental data. This interdisciplinary project bridges astrochemistry and surface science, with the potential to deepen our understanding of how interstellar icy dust particles drive the chemical evolution of the universe. To achieve the objectives of the STARS project, I will conduct my research at the University of Antwerp’s Chemistry Department under the supervision of Prof. Neyts, a leading expert in molecular simulations. This project will also strengthen my academic profile, preparing me for advanced funding opportunities and enabling me to establish my own research group.""


**Keywords:** Astrochemistry, Molecular Processes, Computational Chemistry
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Aqueous thermal conversion of biomass to hydrocarbons in the fluid fuel range' (1994-1998).

assistant: **Innovation**

The aim of the project is to produce petroleum-type liquid hydrocarbons from solid biomass in a one-step, aqueous, closed pyrolysis process. The project is based on experience acquired during use of high-pressure pyrolysis for simulating natural petroleum generation processes from solid organic matter, and aims to optimize comparable reactions for biomass feeds by pyrolysis in the presence of water. The optimal product should resemble a light crude oil, and contain a large proportion of hydrocarbons. A complete breakdown of the organic molecules into gas-phase components comprising synthesis gas (CO, CO2, H2) and a subsequent polymerisation through Fischer-Tropsch type reactions is a possible pathway for production of high value products, and it is an aim to try to maximize such reactions relative to simple cracking processes which give high yields of oxygen containing tars. Biomass characterisation by analytical pyrolysis, NMR and conventional biochemical analysis will be used to investigate the hydrocarbon potentials and limiting factors of mixed biomasses for generating liquid fuels. A predictive model based on the compositional analysis will be developed using multivariate calibration on the hydrous pyrolysis yields of representative samples sets. The characterisation will also be used to select samples suitable for microbial preprocessing, either by biochemical transformations of the molecular compositions or through transformation of biodegradable substrates into microbial biomass. The development of the hydrous pyrolysis method is combined with a mapping of the resource basis to identify optimal biomass types for exploitation, both in economic and resource perspectives. The potential for surplus agricultural and forestry biomass to contribute on a significant sca
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'The RowP system by Quiske Ltd is a game changing rowing technique measuring and coaching system for any level of rowers or crew both outdoor and indoors.'.

assistant: **Innovation**

Quiske is a Finnish sports technology startup company. The Quiske team have developed an advanced yet affordable and simple to use RowP product which helps rowers improve their technique. The RowP system gives instant feedback and post-training analytics for on water as well as indoor rowing. The pilot product was first launched in the summer and has since generated interest worldwide. Quiske seeks funding to create a business plan commercialize the product and to reach new markets.The RowP product consists of a lightweight and affordable multifunctional pod which can measure handle or seat speeds and the instant feedback can be viewed on any smartphone display. Advanced algorithms allow analyzing and even comparing the technique of rowers with each other in the RowP cloud service. We are bringing the advanced rowing performance measurements not only to elite competitive rowers but also to the much higher volume indoor rowing market to help anyone learn to row correctly. The RowP system also includes a Virtual Coach to help indoor rowers improve their performance. Indoor rowing is practiced by 100s of millions of people in gyms across the world. However, most people do it with bad technique which doesn’t help improve their fitness optimally.In addition to the innovative Virtual Coach we we will also bring Augmented Reality to make the indoor rowing experience better. The RowP App will be gamified to make it more fun to use and to include sharing of results to social media. Based on request from customers we will also build an iOS version of the App. The feasibility study will result in a business plan to roll out the RowP product and analytics platform globally and to collect and technically validate the features for the commercial RowP product, that our first pilot cus
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Secure Process-oriented Integrative Service Infrastructure for Networked Enterprises' (SPIKE).

assistant: **Concept**

SPIKE will develop a software platform for the easy and fast setup of business alliances.  The project targets two main organisational objectives: first, outsourcing parts of the value chain to business partners (and vice versa, offering such parts in form of services); second, enabling collaboration between members of participating organisations through ad-hoc created as well as predefined business processes. SPIKE will enable collaboration and cooperation between the networked enterprises.  The solution will encompass a semantically enriched service oriented infrastructure including a virtual semantic service bus for workflow control and handling and transformation of messages. At the enterprise interface level, we follow a collaborative process portal approach, capturing the user's working context and seamlessly transmitting it to other applications and services according to the current workflow. This will also enable integration of legacy systems via tailored portlets and connectors. Special focus will be put on the security issues involved; the solution will include an easy-to-administer security infrastructure for the networked enterprise which will provide security services for service and workflow management.The user partners will demonstrate the potential of SPIKE at the case of pilot deployments and use cases, i.e. a collaborative business alliance and two services ready for use in the networked enterprise. Because of its focus, the project will have an impact on organizations of all sizes that want to collaborate with each other. The base SPIKE components will be developed as an open source solution, with a special emphasis on easy adoption and cost feasibility. Where possible, we will build upon and enhance existing open source software. This way, SPIKE will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Gut microbiota-dependent tryptophan metabolism: role in disease pathogenesis and therapeutic target' (MODulATE).

assistant: **Innovation**

Tryptophan (Trp) is an essential amino acid required for protein biosynthesis and is also a biochemical precursor of metabolites which have major effects on mammalian physiology. In the gastrointestinal tract, Trp metabolism can follow three major pathways, all of which are under the control of the gut microbiota: (i) the kynurenin pathway in immune and epithelial cells via indoleamine 2,3-Dioxygenase 1, (ii) the serotonin production pathway in enterochromaffin cells via Trp hydroxylase 1 and (iii) the direct use of Trp by the microorganisms of the gut microbiota into several molecules including ligands of the Aryl Hydrocarbon Receptor. The end products of these pathways play key roles in modulating the immune response, intestinal and metabolic functions and behaviour. Several diseases which involve the gut microbiota in their pathogenesis are also impacted by Trp metabolite. This suggests that the effect of the microbiota in these diseases could be at least partially mediated by impaired Trp metabolism. We recently observed that impaired Trp metabolism by the gut microbiota is involved in inflammatory bowel disease pathogenesis and preliminary data suggest a potential role in other major human diseases.The aims of the current proposal are (i) to identify the components of the gut microbiota, including both bacteria and fungi, involved in the control of the 3 Trp metabolism pathways in the gut, (ii) to decipher the reciprocal equilibrium between the pathways and to evaluate the potential of its modulation as a therapeutic target, and finally (iii) to assess the relevance of these phenomena in human patients.This challenging project will involve multi-disciplinary aspects, from microbiology to metabolism, inflammation and medicine, the use of multiple cutting edge techno
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Testing and up scaling of technology developed under the SOLNOWAT FP7 Project which developed a competitive 0 GWP, dry, atmospheric pressure etching process for use in manufacture of PV solar cells' (DEMOSOLNOWAT).

assistant: **Concept**

Following on the successful results of SOLNOWAT project that commenced in September 2011, this project will focus on up scaling and demonstrating the novel technology that was developed for the photovoltaic manufacturing industry under the first FP7 project.The technology developed and proven in the SOLNOWAT project serves to reduce the water consumption of the cell manufacturing process, focussing on the etching steps, high throughput technology and specific process control -  this follow on project will act as a stepping stone in getting the innovations from the ""lab to the fab"".Under this project specific industrial scale prototype equipment will be built by the participating SMEs and the technology will be demonstrated and tested i.e. the equipment will feature a dry etching tool with high volume/ high throughput system, integrating specific process control.Given the turmoil that exists in the solar industry at this time the funding of this prototype testing would be very difficult without European Funding. Up to 68% of all cells made in 2011 came from China or Taiwan, innovation & significant cost reduction is required if Europe is again to become a player in the PV manufacturing industry.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Improving the spatial resolution of air emission inventories unsing earth observation data' (1994-1998).

assistant: **Innovation**

The overall aim of this project is to use earth observation (EO) data to develop a methodology to improve the spatial resolution of air emission inventories. The customer for the project is the environmental assessment industry (commercial consultancies, research organisations), which produces air quality management tools, to help national and local authorities improve air quality. The methodology will provide a means for producing emission inventories for urban areas, which is more cost-effective than the current approach of commissioning special surveys. The methodology will also help the environmental assessment industry in developing air quality management tools for developing countries. The project will draw on existing EO data sets such as Corine Land Cover, SPOT and Land sat TM. Similarly, existing air emissions data such as Corinair, will be used. The methodology will be validated by drawing on existing urban inventories for representative areas from across Europe. Because the project will draw on existing data sets, it is a low-risk project with a high chance of success.The key measurable objectives of the project are:- develop an EO-based methodology which enables air emission inventories with a spatial resolution of 1km x 1km to be produced;- validate and refine the methodology;- examine how EO data can be used to produce even greater improvement in the spatial resolution of emission inventories (100m x 100m);- undertake a customer assessment and assess the cost-effectiveness of the methodology. In addition to helping the European environmental assessment industry develop new air quality management tools, the project will assist with the implementation of community policies on air quality management. This is a customer-led project. The consortium is led by a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'PRIME (Push Relevantly to Increase Mobile Engagement)' (PRIME).

assistant: **Concept**

The rapid growth of smartphones and tablets pave the way for proliferation of a variety of mobile applications. Push notifications, which provide enhanced communication when compared to SMS, became the de facto messaging tool between application owners and mobile users. However, push notifications are still sent carelessly which results user frustration, low open rates (10%) and decreased user retention. PRIME (Push Relevantly to Increase Mobile Engagement) is cloud service which aims to create the next leap in push messaging by gathering various sensory information from mobile devices analyzing big data and providing real-time insights by using machine learning, data mining and home grown pattern matching algorithms. PRIME will anticipate mobile users’ context, and forecasts their needs from previous usage patterns and dynamic models. PRIME will either send relevant push notification immediately or refer it for a more relevant time in the near future. PRIME anticipates the “prime time” of mobile user and send push notifications accordingly. The dynamic model of PRIME is expected to increase open rates of push notifications among smartphone and tablet users tremendously. PRIME has both benefits to mobile users and mobile application owners. Sending push notifications relevantly increases customer retention due to mobile user satisfaction and increases mobile engagement which in turn increases mobile revenues. The initial research for PRIME has been done by DONE A.S. and funded by TÜBİTAK (Scientific and Technological Research Council of Turkey). The research findings, which are also published in ""Human Computer Interaction International"" 2013 and 2014, demonstrated a 36% user engagement increase and 21% increase in the number of active users. These demonstrated result