RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Development of a multisensor for the supervision of durable bakery products' in the context of a Sixth Framework call.

assistant: **Objectives**

During the production of durable baked goods (hard biscuits, crackers, crisp bread, rusk, ice-cream waffles, etc) and after baking, it is necessary to supervise certain product parameters in well-defined periods of time in order to ensure that the products fulfil the required quality and appearance standards (weight, moisture, physical dimensions, colour). Nowadays, in craft bakeries, the product samples are taken manually from the production line by the operators and then inspected. This inspection consists in most cases just on moisture determination and on the measurement of the product physical dimensions. These parameters are then used to determine the conformance of the product. The determination of the colour, a very important attribute for the consumer, if determined, is done visually. These methods are therefore subjective and not precise enough. The use of more accurate techniques is usually limited to large companies due in one hand to the high costs of more complex and precise devices and in the other hand due to the lack of skilled personnel able to use them. There is an evident need for the development of low cost, user-friendly instrument suitable for at-line use by small and medium size bakeries. The aim of the proposed project is to develop a modular sensor inspection system - SENBAK - for the continuous and automatic supervision of the quality parameters of durable baked goods in production lines. The development of the SENBAK system will be oriented for its use in small and medium size enterprises, in order to provide them with an easy to use and precise tool for product quality control. The SENBAK system will be a low cost system, rugged, simple, able to withstand the harsh condition in bakeries and to make automatic, fast and accurate quality inspec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Innovating goverNment and ciTizen co-dEliveRy for the digitaL sINgle marKet' to be submitted under Horizon 2020.

assistant: **Abstract**

INTERLINK aims to overcome the barriers preventing administrations to reuse and share services with private partners (including citizens) by developing a novel collaborative governance model that merges the enthusiasm and flexibility of grassroot initiatives with the legitimacy and accountability granted by top-down e-government frameworks.  We believe that a solution incorporating the strengths of these two approaches will be able to overcome their individual limitations, namely lack of involvement of private actors, transparency and trust for “top-down” and lack of sustainability, accountability, and legitimacy for “bottom-up” initiatives. To enable this, INTERLINK will provide a set of digital building blocks, called “Interlinkers”, that implement the defined governance model and standardize the basic functionalities needed to enable private actors to co-operate in the delivery of a service (organization, communication, scheduling, monitoring, etc.). In this way, the new shared service will maintain the effectiveness of digital solutions adopted in grassroots initiatives to support self-organization and make collective decisions, and at the same time fulfill the technical and legal requirements necessary for adoption by Public Administrations (PAs). The INTERLINK multidisciplinary consortium will deliver the new governance model and Interlinkers within a technological framework and operational platform based on an open software system leveraging on mobile communications, facilitating the co-production of services between PAs and private stakeholders. The solution will be customised, deployed and evaluated on three use-cases within the partner PAs: the Italian Ministry of Economy and Finance, the Latvian Ministry of Regional Development, and the City of Zaragoza. Less
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Aqueous Proton Mobility near Ions and in Nano-Confined Geometries'.

assistant: **Objectives**

Protons in liquid water posses an anomalously high mobility compared to other ions. This high mobility results from the fact that hydrated protons are not transported as intact units, i.e. by so called mass transport, but rather form defects that diffuse “structurally” through the water hydrogen-bond network. As such, aqueous proton transfer strongly relies on the structure and dynamics of the water network. Many natural and technologically relevant proton transfer reactions occur in the direct presence of ions, proteins or in geometrically confined volumes (e.g. nanopools, nanochannels). We propose to study how the nature and concentration of ionic co-solutes affects the dominant hydration patterns, conversion time-scales and local reactivity of the proton. We will also study how the structuring of the water network in nanopools and nanochannels affects the rate and mechanism of proton transfer. This will be experimentally realized by powerful spectroscopic techniques including femtosecond mid-infrared pump-probe spectroscopy and time-domain terahertz spectroscopy, which are available at the proposed host organization AMOLF (FOM) in Amsterdam, The Netherlands. Compared to conventional linear spectroscopies, these non-linear techniques are ideally suited to discriminate between the large number of sub-ensembles of local hydration patterns of the aqueous proton present in solution. The techniques will allow the measurement of the evolution of these sub-ensembles in time. The researcher, Dr. Ottosson, has a strong background in X-ray spectroscopic investigations of aqueous solutions from his Ph.D. work at Uppsala University, Sweden, making him an ideal candidate for this challenging project. With the guidance of the host scientist, Prof. H.J. Bakker – a world-leading expe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'commercialisation TridimensiOnal Nanoporous ALumIna Templates' to be submitted under Horizon 2020.

assistant: **Abstract**

One of the results obtained under the project nano-TEC (ERC-StG-240497) is an alumina template with three-dimensional nanopore architecture. This novel structure and its fabrication procedure have been the subject of a patent that has been recently filed. This structure has the novelty of being composed not only by vertically aligned pores, but also by tailor-controlled horizontal pores interconnecting them with their closest neighbour creating a three-dimensional net of nanopores. This template can also be used for the fabrication of highly ordered three-dimensional network of nanowires. Controlled and uniform assembly of nanowires with high scalability is still one of the major bottleneck challenges in fields such as energy harvesting, sensing, and device integration for electronics or catalysis. Moreover, since the spacing between horizontal interconnected nanopores is tuneable the colour of the alumina film can be controlled showing rainbow-like luminous colours that change with the angle of view, like in a Morpho butterfly wing. The work already undertaken under the nano-TEC project requires further investment in order to explore larger area, mass-production of these templates, for a further understanding of target markets and their limitations (regarding cost, aluminium purity, sizes, etc.). Finally, the objective will be to place some of the ERC-StG Nano-TEC results at market level.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Small and medium enterprises in Europe and East Asia: competition, collaboration and lessons for policy support' under Fourth Framework.

assistant: **Concept**

This two year study will evaluate the competitiveness of European SMEs vis-a-vis their counterparts in East Asia (Japan, Korea and Taiwan), using enterprise benchmarking to identify the nature of their technological differences in selected low, medium and high technology manufacturing activities. It will trace observed differences within comparable activities to variations in human resource availability, development and management; the strength and relevance of network linkages with SMEs and with large enterprises; the nature and sophistication of consultancy and advisory services; links with the S&T system; the financial system supporting innovation; and cross-national, national, local and municipal government initiatives to support productivity, skill development and marketing. The detailed firm-level analysis and benchmarking will allow the identification of 'best practice' models of SME technology development; it will also provide data that can be used in statistical analysis to identify rigorously the extent and causes of deviation from the technological frontier. This will clarify the nature of the emerging competitive challenge facing European enterprises from the Asian 'Tigers', and the prospects for fruitful collaboration between them. The analysis of support systems in Asia, which are known to be strong andpervasive, but whose detailed operations are not well understood, will lead to policy recommendations for strengthening the science and technology support system for SMEs and improving the efficiency of networks and clusters in Europe. The project will create a data bank on micro-level technological activity and competence in the activities studied; this data base can later be expanded to other activities to provide inputs into S&T policy analysis in the EU.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'IPUD – An Implantable Peritoneal Ultrafiltration Device that actively and continuously prevents fluid overload in diuretic resistant heart failure patients.' (IPUD) under Horizon 2020.

assistant: **Objectives**

Fluid overload (congestion) is a classic clinical symptom and cause of distress among heart failure (HF) and chronic kidney disease (CKD) patients. Diuretics are currently the gold standard treatment but of the 26 million heart failure patients annually around the world, over one third are diuretic resistant. Current solutions for fluid overload in diuretic resistant patients such as IV diuresis, ultrafiltration therapy and peritoneal dialysis all carry complications and are acute treatments which do not prevent recurrence.IPUD improves the clinical condition of fluid overloaded patients by continuously removing extracellular fluids with a unique implantable peritoneal ultrafiltration device, operating non-aggressively and independently from the kidneys’ function. IPUD is minimally invasive (laparoscopic approach) and the flat absorption device interfaces with the intraperitoneal membrane and applies a hydrostatic pressure gradient. It then continuously (24/7) and slowly absorbs systemic isotonic extracellular fluid and drains it to the urinary system preventing recurred accumulation. The device has a projected service life of 3 years and recharging the device has been made simple for the patients via wireless charging, needed on a weekly basis.The global congestive heart failure treatment device market is worth almost $6 billion and is poised to grow at a CAGR of around 6.4% over the next decade to reach approximately $17.8 billion by 2025. IPUD will be sold directly to hospitals and clinics for approximately €30,000 through collaborations with the major distributors of heart failure devices.Our senior team has over 50 years’ experience in the cardiology and medical device sectors combined with extensive academic education. We have raised €1 million in funding. Our ful
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'RNA interference as a potential control of peste des petits ruminants' (2002-2006).

assistant: **Innovation**

The proposal consists of a laboratory-based training project of two-years. The research and training topic concerns a new approach for the control of the pestedes petits ruminants (PPR). PPR is a highly contagious and fatal disease of small ruminants wide ly distributed in sub-Saharan Africa and the Arabian Peninsula. In spite of recognisable advantages of the vaccine developed until now, there are some limitations, which are to be overcome (poor vaccine thermal resistance and decrease of vaccine efficiency due to maternal antibody interference). Furthermore, vaccines are preventive tools that induce an immune response protecting the animals before the initial contact with the virus. Then, there is an interest to develop a curative tool that could help in th e control of the virus replication when animals are yet infected.It was recently shown that double stranded RNA molecules (dsRNAs) promote potent and specific gene silencing in virtually all eukaryotic organisms, a phenomenon called RNA interference" (RNA i). RNAi in mammals may be induced in basically two different ways: plasmids expressing short hairpin RNAs (shRNAs, functionally identical to siRNAs) or virus vectors (adenovirus, retrovirus) expressing shRNAs. The project goal is to achieve silencing of different PPRV genes through siRNAs and to look at the effects on the PPRV replication and protein expression in vitro and in vivo. Initially we will analyse the efficiency of shRNAs expressed from plasmids and designed for transient gene silencing in cell cultures.Then adenoviral vector or a specific goat retroviral vector will be prepared with the efficient siRNAs and used to inhibit PPRV gene expression and replication in cell culture system. In sequence, we intend to conduct in vivo studies in goats, the natura
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'A novel smart trap station as an Internet of Things surveillance solution to remotely count and  identify the species of disease-carrying mosquitoes'.

assistant: **Innovation**

BIOGENTS is a world leader in the development and production of surveillance Traps for Mosquitoes, a key supplier for public and private organizations. BIOGENTS, together with IRIDEON, a specialist in IoT sensor applications, and TEIC, a specialist in bioacoustic species recognition, want to address the problem of disease-carrying mosquitoes that invade Europe due to climate change. Our goal is to prevent the loss of billions of Euros, the infection of millions of citizens and most importantly, the deaths of thousands registered every year worldwide. BIOGENTS and its competitors have a conservative business model: continuously develop increasingly efficient trapping methods, for the best price. However, the customers’ real need is to get reliable information about mosquito populations in a given area, and thus have to periodically inspect traps manually. This is where the real costs are; therefore the next disruptive leap lies in making the traps smart. REMOSIS t will attract insects with great efficiency, and perform stand-alone field monitoring, by automatically counting insects, identifying species, and transmitting the data wirelessly. This reduces inspection costs by 80% improving surveillance programmes, which will prevent unnoticed disease outbreaks, and will save lives. With the new electronic trap, we will be the first in the world to combine human mimicking with automatic pest information in their value proposition. This allows a whole new population of consumers to establish surveillance programmes that were only accessible to those with significant resources. BIOGENTS and IRIDEON will produce the solution, and use their own customer and distributor networks as initial commercial routes, which already cover Europe, USA, Australia, Latin America, Africa and Mi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Targeting and exploiting B cell functions for treatment in cardiovascular disease', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Cardiovascular disease (CVD) mortality and morbidity is predicted to increase in Europe and worldwide in the next decades due to aging and the rise of diabetes and obesity. The link between metabolic and inflammatory disease is getting stronger, raising hopes for novel therapeutic targets to be exploited clinically. Clinical evidence generated by the Academic partners of the Athero-B-Cell Consortium demonstrates that CVD is associated with pro- and anti-atherogenic B cell responses. We aim to use existing proteomic, transcriptomic and miRNA data generated from large-scale clinical studies in previous EU-funded collaborative efforts to decipher the pathways that favor pro- and anti-atherogenic B cell functions in order to unravel a new set of therapeutic targets and refine potential vaccine strategies for CVD. The selection and validation of targets will be made possible by substantial technological advance achieved by the participating SMEs that are world leaders in the field of bioinformatics, genetic modification including humanised mouse models, and 3rd generation antisense drugs with locked nucleic-acid (LNA) design that are in Phase II human trials.  Academia-led innovation includes high-resolution methodologies such as CyTOF and ImageStream to interrogate available samples from clinical trials and the ability to validate the targets of interest in accredited models of CVD. The validation in vivo and in vitro of such targets will feed into the SME pipeline accelerating the process of drug discovery. The recent clinical success of 3rd generation antisense drugs underscores the advantage of the Athero-B-Cell approach: the seamless transition from validation tools to clinical applications. Harnessing protective or abating unwanted B cell responses has the potential to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Impact of climate change on twilight zone fishes during early-stage development' (PLEASE) under Horizon Europe.

assistant: **Objectives**

Twilight zone (TLZ) hosts the largest and least exploited fish stocks of the worlds oceans. These fishes play a key role in ecosystem services, such as sustaining other relevant marine species and global carbon cycle. The TLZ research is still in its infancy, but the high biomass has raised interest in its exploitation, mainly as fish meal, but also as nutra-pharmaceutical compounds. Moreover, climate change is altering the environmental conditions in ways, of which we do not know how life in TLZ will be affected. It is alarming that this vast ocean domain is at risk even before any of the potential consequences of fishing are fully understood. One of the most threaten and less studied aspects of the TLZ is the early life stage of its fishes. PLEASE project aims to fill this gap of knowledge. The first objective is to set background information about basic biology of the embryonic and larval development of different TLZ fishes. It will be achieved by establishing a suitable methodology for assisted reproductive technology in laboratory conditions, since the wild TLZ fishes are vulnerable to captivity. The reproductive methodology will be transferred to the non-academic partner, for developing pioneered aquarium exhibitions. The second objective is to examine the developmental responses of the embryos and larvae due to ocean warming and acidification under climate change scenarios. It will be monitored via the developmental variability, metabolism, physiology, morphometry, and mortality rates of the specimens. The outcomes of the project will be of paramount importance to forecast the impact of climate change on the community of TLZ fishes and will open a new era for more investigation in this pristine and vulnerable zone of the planet. Finally, a range of interactions w