RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'A novel Holistic Automated Analytics System for IT infrastructure management that proactively identifies and prevent IT operational threats.' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

A typical Data Centre is comprised of multiple hardware and software components from different manufacturers, each with their own management tools, silo dashboard and limited sharing capabilities of business operations control data. This problem seems to get worse as IT-based companies are moving towards dynamic and complex virtualized and cloud environments. Moreover, when working on system´s safety, disrupting even one element of this fragile infrastructure runs the risk of affecting other systems, causing serious damage to the business. The average reported incident length is of 86 minutes, resulting in an average cost per incident of about $690,200.CorreAssess™ is an innovative game-changing Data Center Optimization Management system for business IT leaders that empowers companies with a complete visibility and control on all their IT infrastructure, through accurate detailed analytics insights delivered on a daily basis. It helps to generate valuable information for wise usage of IT infrastructure investments, resource allocation efficiency, IT alignment to defined SLAs, compliance, service availability, data recovery risks and easier cloud migration, alerting in advance before threats impact the company business. With CorreAssess™ companies will be able to reduce up to 25% the infrastructure investment costs and prevent risks of business failure by improving business continuity up to 80%.So far, €2M million have been raised and invested into the development and testing of the system to ensure its robustness and efficiency and move into the next stages of commercialisation. Within the overall project, we intend to finalise systems engineering and conduct a wide pilot trial within Europe. Current IP portfolio will be expanded to EU.The proposed work in Phase 1 of th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'EUropean Supersites for Atmospheric Aerosol Research' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

The objective of the project EUSAAR is the integration of measurements of atmospheric aerosol properties performed in a distributed network of 20 high quality European ground-based stations. This integration contributes to a sustainable and reliable operational service in support of policy issues on air quality, long-range transport of pollutants and climate change. The project will be coordinated by CNRS in Clermont-Ferrand and activity leaders are world-recognized experts in the field of aerosol research.The lack of coordination programs for non-regulated measurements of aerosol properties is considered a major gap in Earth Observation that urgently needs to be filled. The objective of the networking activities is to ensure most efficient use of available resources by:1- harmonization and validation of current measurement of particle optical, physical and chemical properties performed at Supersites as these are critical to ensure their scientific value (N2, N3, N4);2- centralization of the validated measurements in a common data base accessible to all users (N5);3- spreading well practices and disseminate information on new protocols both within and outside the project.Trans-National Access (TA1-TA11) is provided for 11 Supersites with long record of international access, outstanding instrumentation for atmospheric research and highly relevant long-term monitoring data series. The joint research activities have the common objectives to develop affordable and sustainable solutions to improve monitoring strategies and products that will advance up-to-date data reporting across Europe. This concerns retrieval of the aerosol column with a novel technology (JRA1), development of a new generation of humidity-controlled instruments (JRA2) and new methodologies for real-time
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Global Stakeholder Platform for Responsible Sourcing' (RE-SOURCING), addressing dissemination and exploitation.

assistant: **Impact**

The proposed project will set up an international platform on responsible sourcing (RS) that: 1. facilitates the development of a globally accepted definition of RS, 2. develops ideas for incentives facilitating responsible business conduct in the EU, supporting RS initiatives, 3. enables exchange of stakeholders for information exchange and promotion, 4. fosters the emergence of RS in international political fora, and 5. supports the European Innovation Partnership on Raw Materials. To achieve the above mentioned objectives, the platform will connect experts and stakeholders by means of a physical element (“Platform Spaces”) and digital element (“Digital Ground”):  The Platform Spaces will allow practitioners (i) to gain a hands-on and peer-to-peer learning experience in workshops and site visits to exchange and learn from enabling factors, instruments and tools facilitating RS initiatives and business conduct for practitioners, and (ii) to engage with stakeholders at international conferences to further the concept of RS on the global political agenda.The Digital Ground will (i) enable, through innovative digital tools such as digital conference spaces and webinars, more easily connect international players and engage them in networking, promotion and information exchange activities, and (ii) synthesise and make easily accessible ideas that incentivise RS initiatives and responsible business conduct.  The proposed project will feature important Flagship Cases of mature and well-established RS initiatives for raw materials highly relevant for Europe’s future energy, mobility and infrastructure development. By engaging international experts and stakeholders via the digital and physical platform element, the project team will be able to engage these initiatives into mutu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The impact of developmental exposure to weak (environmental) estrogens on the incidence of diseases in target organs later in life' (1998-2002).

assistant: **Concept**

The incidence of cancer is increasing steadily in tissues that are regulated by estrogens. It has been proposed that the increased cancer incidence but also fertility problems in wildlife and humans is caused by an increased exposure to environmental compounds that mimic endogenous estrogens. In the current project we will perform model studies to determine the potential impact of developmental exposure to weak estrogens on the incidence of diseases in the mammary gland, testis, prostate, ovary and brain. The project aims to improve current testing strategies, and provide molecular markers that can be used in clinical research to quantify the involvement of dietary and environmental estrogens in the ethnology of major human diseases.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Invasive Alien Species: towards Improved MOdeling tools through Virtual ecology' under Seventh Framework.

assistant: **Concept**

In Europe and worldwide, many plant communities are increasingly becoming dominated by introduced species. Invasive alien species (IAS) have caused severe environmental changes globally by altering species composition and ecosystem function and are considered a major threat to biodiversity. Consequently the Action Plan for Biodiversity advocates a comprehensive strategy at EU level to reduce the impact of IAS. This proposal aims to merge perspectives from plant evolutionary, functional and community ecology with those from simulation modeling to reveal the processes underlying plant invasions and improve our statistical framework for studying and preventing them. There are 4 research objectives: the first two objectives rely on theoretical modeling while the third and fourth aim to apply the knowledge acquired from the theoretical modeling part to empirical data in the French Mediterranean and Alpine region. In particular, the project will 1) develop and validate a process-based simulation model to explore how environmental and biotic filters for local community assembly are reflected in invasion patterns using virtual data, focusing on the importance of the spatial scale and of different mechanisms of competition; 2) test the ability of current statistical methods to disentangle patterns resulting from overlaying filters and provide guidelines for improved method performance using simulated data; 3) apply the improved statistical methods on French Mediterranean and Alpine plant communities to explore shifts in dominant invasion processes across environmental gradients and invasion stages; 4) attempt to parametrise the developed process-based model through a novel Bayesian approach in order to quantify the relative importance of environmental and biotic filters for succ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Investigations of the absorber component of a solar desiccant air conditioning system' under Sixth Framework.

assistant: **Concept**

Goal of the proposed research project is to investigate a solar driven liquid-desiccant air conditioning system for different climatic conditions and building loads. The main advantage compared to conventional and other solar driven cooling systems is, t hat the electricity demand is replaced by very low temperature heat demand. This demand can be supplied by renewable energies, e.g. even by flat plate solar collectors.The proposed research project shall be part of a project-cooperation with Universities in Canada and Australia. Due to the fact that the energy consumption for air conditioning increases rapidly in developed countries, the new air conditioning technology has the potential to reduce the electricity consumption and herewith CO2 emissions in Europe in a relevant scale. The key component of a liquid desiccant cooling system is the absorber/regenerator unit. In the absorber, humidity of the air is absorbed in a salt solution and the air is dried. Afterwards, water is evaporated in the dried air, and cools down the air meanwhile. The poor salt solution is recovered with low temperature heat.The absorber can be realized with various geometries. In the proposed research project, investigations of a thin-film-parallel-plate construction shall be carried out. In the first part of the project, the overall system behaviour of a liquid desiccant air conditioning system shall be elucidated with system simulations. The system simulation tool TRNSYS shall be used. One outcome of the first part of the project shall be specifications of the absorber, like suitable dimensions, flow rates and temperatures, as well as concentrations. Furthermore, reference conditions, building loads, the control strategy and a target function needs to be defined. In the second part of the pro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'MULTILEVEL INTERVENTIONS TO PROMOTE MENTAL HEALTH IN SMEs AND PUBLIC WORKPLACES' (H-WORK), addressing dissemination and exploitation.

assistant: **Impact**

Recent reports indicate an increase in mental health problems among the general EU population in recent years.  Small and Medium-sized Enterprises (SMEs) and public organisations are particularly vulnerable as they have often scarce knowledge and resources to effectively manage workers’ mental health and wellbeing. The general aim of the H-WORK project is to design, implement and validate effective multi-level assessment and intervention toolkits providing new products and services to promote mental health in public organisations and SMEs, evaluate individual and organisational outcomes of the adopted measures, and provide recommendations for employers, occupational health professionals and policymakers. The project aims to design, implement and exploit an integrated toolkit (H-TOOLS) which will provide managers and CEOs to effectively assess organisational psychosocial risk (HAT), implement the most appropriate interventions (HIT), and evaluate individual and organisational outcomes of the adopted measures (HET).  Implementation of the H-WORK Toolkits will occur in ten intervention sites across five European countries, including five public organisations (healthcare, higher education, governmental) and five SMEs. Moreover, the data and experience generated during the implementation process will allow for development of further H-WORK products and services. Specifically, H-WORK will design, test and deploy the H-WORK Innovation Platform which will include novel digital services such as Benchmarking Calculator and Decision Support System that will facilitate the spread and uptake of the H-WORK solutions across Europe, and ensure the long-term sustainability of the project outcomes. The H-WORK project will significantly contribute to coordinated strategies for occupationa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Facility for Large-scale Adaptive Media Experimentation' (FLAME).

assistant: **Innovation**

The Future Media Internet (FMI) will be driven by evolving existing over-the-top (OTT) solutions towards a stronger integration with emerging programmable communication and computing infrastructures to address consumer demand for personalised, interactive, mobile and localised media experiences. Creating a trusted platform that brings together technology, creative sectors and consumers in the development of pioneering media applications and services will be crucial to drive European innovation and competitiveness. FLAME will address this goal by establishing an FMI ecosystem based on the largescale experimentation of novel FMI products and services using real-life adaptive experimental infrastructures encompassing not only the compute and storage facilities but also the underlying software-enabled communication infrastructure. FLAME’s ecosystem will engage both the creative industries (broadcast, gaming, etc.) and ICT industries (telcos, services) responsible for online distribution, broadcast, communication, and distribution of digital content. Through acceleration methodologies and an advanced experimentation platform (surrogate service management, adaptive service routing, experimental media service chains and experimentation toolbox), FLAME will allow industry, SMEs and entrepreneurs to conduct experiments in real-life experimental infrastructures and gain insight into the performance, acceptance and viability of solutions. FLAME’s innovation potential will be maximised by establishing FLAME Trailblazers (Bristol, Barcelona) to show the way for FLAME Replicators across Europe using a replication process based on best practice sustainability, governance, and engagement models, and infrastructure standards and specifications. A 3rd party investment strategy will creat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Development of new models for cancer chemotherapy response prediction' (DONMFCCRP), addressing dissemination and exploitation.

assistant: **Impact**

The ability of cancer cells to acquire simultaneous resistance to different drugs is a significant obstacle to successful chemotherapy. Today there are no clinically useful predictive markers of a patient's response to chemotherapy. The use of gene express ion patterns of well-defined chemotherapy-resistant and sensitive cancer cell lines and assaying their potential for predicting the response to chemotherapy in conjunction with the prognosis on a pre-characterised set of cancer patients can increase the ef fectiveness in searching for new prediction models. During my Marie-Curie fellowship we have identified genes associated with the resistance against 12 anticancer drugs. For example we were able to construct a predictive model for doxorubicin resista nce identifying the 80 genes with highest impact on the resistance. First, we will validate these already identified genes by an independent method. The validation will enable the fine-tuning of the prediction model, the selection of a gene list for cust om DNA chips and stem-cell investigations. About 51% of the already identified genes are EST¿s, where the biological function of the gene is unknown. These genes represent novel gene candidates responsible for chemotherapy resistance. Our aim is to perfo rm functional investigations in order to describe the function of these genes. This combines genome-wide expression profiling after RNA interference and stable transfection in order to detect pathways associated with these genes. Our major aim is to estab lish the prediction model for various cancer types. We plan to perform predictive analysis for lung, colon, breast and stomach cancer. This objective includes the build-up of a new tumour-bank focused on drug resistance and testing of self-synthesised cust om chips bas
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Engineered Heart Tissue (EHT) Devices based on Ion Conductive Guanosine-Quadruplex (GQ) Hydrogels: A Route to Advance In Vitro 3D Cardiac Tissue Models' in the context of a Horizon Europe call.

assistant: **Objectives**

In this project, a micro-engineered heart tissue (EHT) device that will advance the physiological relevance of current in vitro 3D cardiac tissue models will be developed. In moving towards this goal, this project will synthesize conductive guanosine-quadruplex (GQ) hydrogels and implement them as cell scaffolds in EHT devices. Key aspects of biomaterials design are the unique conductive and hierarchical 3D fibrous network and the good biocompatibility of GQ hydrogels, which will support cardiac cell culture. Upon integration in the EHT platform, the mentioned properties of GQ hydrogels will enable electrical stimulation of embedded cardiac cells under mild pacing voltages, thereby promoting the formation of morphologically and functionally mature cardiac tissue. GQ hydrogels will demonstrate high flexibility and potentially broad utility as a biocompatible and conductive biomaterial for in vitro cell experimentation. The outcomes of this project will expand the horizon of pre-clinical 3D cardiac tissue models, paving the way for future approaches to drug testing and personalized cardiovascular medicine.


**Keywords:** G-quadruplex, Conducting Hydrogels, 3D Cardiac models, Engineered Heart Tissue (EHT), Rhythmic Beating