RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'The characterisation of a putative human cell division cycle gene and study of its possible role in intestinal differentiation', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

During my present research on the intestinal enzyme lactase I have found a putative human cell division cycle gene. I wish to follow up this initial finding, and isolate and characterise a complete cDNA corresponding to this gene. This will enable the analysis of the relationship of this transcript to putative homologues identified in yeast and other organisms. I propose to investigate the pattern of expression using RT PCR, Northern blotting and in situ hybridisation techniques. I also aim to make specific antibodies for analysis of the resulting polypeptide. I will study cell lines which are being used as models for intestinal differentiation in addition to cell lines in which the cell cycle call be regulated by drug treatments. I also aim to clone and characterise the promoter region of this gene to enable future studies on the regulation of expression.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'What is a well written text? Holistic and analytic assessment of text quality in L1 and L2 Italian' (WeWriTe) under Horizon Europe.

assistant: **Objectives**

The quality of a written text is often described in figurative terms, such as clearness and smoothness. The explicit description of what makes a text clear and smoothly flowing is a challenging task, probably because the readers perception of a text is influenced by multiple variables, related to the way information is structured, and how the writer employs the lexical and morphosyntactic resources of a language. The difficulty in translating the readers perceptions of a text in measurable descriptors leads to challenges in literacy education. For instance, how can educators explain what makes a text clear and smoothly flowing? What are the crucial aspect to focus on when giving feedback or conducting formative assessment? Answering these questions is of fundamental importance, given that writing literacy may have a considerable impact on employability, social participation and lifelong learning.  This project aims to explore the relationship between the holistic evaluation of texts, carried out by expert evaluators, and their linguistic characteristics, to understand to what extent it is possible to identify objective and measurable properties that distinguish texts perceived as well written, compared to those with less positive ratings. For this purpose, we will establish a corpus of argumentative and narrative texts, written by university students, who are L1, L2 (or L3) speakers of Italian, a language that has received little attention so far in international research on writing. The methods of analysis involve the use of linguistic indices identified by previous research, which focus on the lexical and morphosyntactic complexity of the texts, and their integration with new indices, based on the Basel model of text analysis. This model contributes to a deeper unders
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Universal prevention of maternal perinatal mental disorders and its implementation as normalized routine practice' (2021-2027), addressing dissemination and exploitation.

assistant: **Impact**

Maternal mental disorders are the most common complications during pregnancy and within the first year after childbirth (defined as the perinatal period) and are the leading cause of maternal suicide. Affected mothers cannot function properly, causing a devastating impact on the entire family. Effective primary prevention interventions are urgently needed. However, the current scientific evidence is insufficient to implementing primary preventive programs at the population level.I aim to establish the effectiveness of universal preventive interventions for maternal perinatal mental disorders and to support their implementation as normalized routine practice in global healthcare services. Integrating classical and emerging methodological frameworks (family systems, self-determination theory, and normalization process theory), as well as the perspective of patient and public involvement in research, I will: (a) Develop a personalized mobile-Health preventive intervention for mothers and their partners, which integrates evidence-based psychological components and personalized health recommendations; (b) Test preventive intervention effectiveness for reducing the incidence of maternal depression and anxiety disorder, reducing father/partner symptoms of depression and anxiety, and promoting child health and development; (c) Apply a causal methodology, to pinpoint the underlying mechanisms for the effectiveness of the preventive intervention; and (d) Understand the implementation process and identify the factors that can promote or inhibit implementation.With the multidisciplinary team that I lead – and a large-scale hybrid effectiveness-implementation trail in real-world maternal health services – this research programme promises to be the first in its field. The resulting r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Diversity Outside In: A new era in musculoskeletal modelling by integrating in-vivo parameters to reflect  human heterogeneity.' (2021-2027) targeting Horizon Europe.

assistant: **Abstract**

Musculoskeletal disorders, affecting muscles, bones, joints, and associated tissues, are the leading cause of disability worldwide today. To guide professionals in preventing and treating musculoskeletal disorders, musculoskeletal models serve as powerful tools. Given that these disorders present differently between sexes and throughout the lifespan, it is crucial to include model parameters that reflect this diversity. However, while it is widely recognized in medicine and science that women and men are not simply scaled versions of one another, the field of biomechanics still relies on linear scaling of musculoskeletal models based on male bone geometry and mixed-sex muscle parameters. Datasets or models capturing the relationship of model parameters across sex, age, and genetic background are lacking, leading to incorrect personalized models. I propose to develop an innovative methodology for rapidly generating accurate, personalized musculoskeletal models that account for age and sex-specific variations. To this end, I will pioneer a highly challenging and unique experimental setup and collect data that spans both demographic factors and multiple levels of model parameters from in-vivo measurements in a population study. With this, I will develop the first musculoskeletal models in which age and sex differences are accurately represented. I propose a morphometric scaling technique, which is a novel approach, integrating full-body shape data with demographic information, to enable rapid and accessible generation of these accurate personalized models. This will set a new standard for both practical applications and research settings. Finally, these models will be used in simulations to explore how age- and sex-related differences impact musculoskeletal loading during
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Multi State Memory in Artificial Multiferroics' in the context of a Horizon 2020 call.

assistant: **Objectives**

Our digital universe is doubling in size every two years, so that by 2020, it will contain nearly as many digital bits as there are stars in our physical universe! Existing memory technologies are approaching their physical storage limitations as miniaturisation of electronic devices continues. This requires significant development of advanced next generation data storage technologies to sustain consumer demand for increasing levels of data creation. New materials and technology to store more data in smaller area are required. There is a strong argument in favour of investing in multiferroic material that is still at a distance from a marketable position. In this proposed project we will investigate the prospect of exchange bias coupled artificial multiferroic material for high density memory device to overcome the market demand.In recent research, multiferroic tunnel junctions (MFTJ) have excited enormous interest for high-density memory devices. In this project, we propose a heterostructure of ferromagnetic (FM) and ferroelectric (FE) materials where the interface becomes antiferromagnetic layer and creates exchange bias (EB) coupling with adjacent FM layer. Due to induced EB, the system will add additional functionality giant magneto resistance (GMR) along with tunneling electro-resistance (TER) and magneto-resistance (TMR) in a single MFTJ, and allow multiple resistive states per memory element at very low dimension where multiple bits can be stored. During the proposed project magnetoelectric process in artificial multiferroic systems will be investigated to unveil possible nanoscale coupling between different ferroic parameters, magneto-electric transport processes and effect of exchange bias on them. Heterostructure thin film with high degree of quality will be s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The next step towards the elimination of iodine deficiency and preventable iodine-related disorders in Europe' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

The iodine status is a primary determinant of thyroid disorders, which are a major cause of morbidity, particularly in women. In addition, even mild-to-moderate iodine deficiency during pregnancy is related to neurocognitive impairment in the offspring. Iodine deficiency imposes tremendous costs on the health-care systems of affected regions, but can easily be prevented by iodine fortification programmes. In many countries, iodine deficiency receives surprisingly little publicity.The initial EUthyroid consortium evaluated European prevention programmes against iodine deficiency and uncovered major limitations including the low awareness on the importance of iodine for healthy living. EUthyroid2 will now fill important gaps in the prevention of iodine deficiency in Europe and beyond. The main objective of EUthyroid2 is to improve the low awareness with respect to iodine deficiency-related risks in adolescents and young women. The major aim is to find best practice models for accessing and informing them to increase their awareness and to improve their iodine status in order to lay the foundation for their own thyroid and general health and that of their offspring.Implementation studies and community-based randomised-controlled trials will be conducted with the objective of increasing iodine-related awareness in adolescents and young women up to age of 24 before pregnancy. The interventions are multimodal and performed in the two settings educational system and ambulatory care in eight study regions. As public health project EUthyroid2 is not only science, but will also serve our societies. Therefore, dissemination of findings to various sectors of our countries and the EU will be of utmost importance. By finding best practice models to raise the awareness on the importan
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Innovative Production Machines and Systems (I* PROMS)'.

assistant: **Innovation**

The proposed Network of Excellence for Innovative Production Machines and Systems (I*PROMS) will address the area of production research in an integrated manner in order to reshape the area and overcome its current fragmentation. The Network will integrate the activities of all leading EU research institutions in the field of production research These institutions possess wide-ranging and complementary human and material resources. This will enable TPROMS to cover all future research priorities in the field without being prematurely restricted to particular, narrow topics that could lose their significance with time. I*PROMS will develop concepts, tools and techniques enabling the creation and operation of flexible, re-configurable, fault-tolerant and eco- and user-friendly production systems that can react to customer needs, environmental requirements, design inputs, and material / process / labour availability to manufacture high quality, cost-effective products. Initially, TPROMS will address the six 'Manufacturing Challenges for 2020', namely, Concurrent Manufacturing Integration of Human and Technical Resources, Conversion of Information to Knowledge, Environmental Compatibility, Reconfigurable Enterprises, and Innovative Manufacturing Processes and Products. Four TPROMS clusters will prosecute research on those themes: Advanced Production Machines (APM), Production Automation and Control (PAC), Innovative Design Technology (IDT) and Production Organisation and Management (POM). At present, TPROMS comprises 30 member institutions representing 14 European countries. They will commit 141 research staff and 69 PhD students to prosecuting the joint programme of activities developed by the Network. In addition to the core research partners, I'PROMS will also comprise as
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'TRANSFER OF AN INNOVATIVE ELECTROCHROMIC WINDOW AND DISPLAY TECHNOLOGY TO THE EUROPEAN NTBF AND SME SECTORS'.

assistant: **Innovation**

The project concerned a novel electrochromic technology based on transparent nanostructured metal oxide films modified by redox chromophores that had been developed in the course of a recently completed Joule II project in nanocrystalline solar cells. The objective was to develop and transfer the technology to two European companies with the capacity to exploit it, namely Pricer AB for programmable shelf edge labelling and Donnelly Mirrors for an electrochromic rear-view mirror.For the mirrors application a working laboratory scale prototype was produced and demonstrated. But Donnelly (which is a subsidiary of Donnelly Corporation, a major US company) is already strong in conventional dimmable mirrors based on their proprietory electrochromic technology and decided not to take the nanochrome application further now (because of the capital investment costs), and for the time being will stay with their proprietory technology.For shelf-edge displays the applications work was dependent on Pricer's input to the development of display driver software. But this part of the project was compromised when Pricer experienced trading difficulties and had to refocus its business away from this area of interest. As a consequence of this the labelling application was not taken through to implementation.NTera (formerly Nanomat) has gone on to develop other applications of their proprietory nanochromic materials (including displays) which now account for about one third of their effort. In the displays context Ntera has demonstrated its prototype capability to produce flat panel 'printed paper quality displays'. Other interests include batteries and sensors, which together account for another third of their effort. The remainder is devoted to IPR management. Extensive license agreements
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'SPP Regions'.

assistant: **Objectives**

The SPP Regions project is aimed at promoting strong networking and collaboration at both the European and sub-national regional level on sustainable and innovative procurement (SPP/PPI), to help promote and embed capacity building and knowledge transfer. At the regional level networking will be promoted to build capacities and transfer skills in sustainable and innovative procurement implementation, and to collaborate directly on tendering for eco-innovative solutions. New networks will be established, or existing networks strengthened in 7 European regions (Copenhagen, Rotterdam, Torino, Bristol, Barcelona, West France and Gabrovo). Networking activities will include an intensive capacity building programme and collaboration on at least 6 tenders per region - 42 in total.At the European level a Sustainable Procurement and Innovation Network will be launched, expanding on the existing Procura+ Campaign. In-depth research will be conducted into European best practice relating to a series of key SPP/PPI topics (market engagement, life cycle costing, output/performance-based specifications, circular procurement) by a series of experts in consultation with network participants. A series of European seminars and expert workshops will be organised, together with an ongoing webinar series, and the annual presentation of a PPI award for European best practice.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'zebrafish model to study human hypertension' in the context of a Seventh Framework call.

assistant: **Objectives**

Kidney dysfunction is central to hypertension. Mutations in the WNK/SPAK-OSR1 pathway cause human hypertension by modulating salt transport. Yet, just when the physiological actions of these proteins appear clear, contradictory data raise questions about their effects, and leave investigators confused about physiological roles and mechanisms of disease. Here, we propose to develop a novel zebrafish model system to permit us to study how NaCl transport is regulated.Our groups have used variety of approaches to study the thiazide-sensitive Na-Cl cotransporter (NCC) over time. We have, however, been frustrated by the inability to study mechanisms of transporter regulation in situ. Organismal solutions to problems of terrestrial life, however, often evolved from challenges encountered during aquatic life. Fish electrolyte homeostasis is maintained, therefore, by a panoply of proteins that are conserved. Fish kidney develops first as pronephros with tubules homologous to nearly every mammalian nephron segment. Studying the pronephros offers excellent experimental conditions throughout.Here, we propose to utilize the unique morphological resources available through the Bachmann group to develop a zebrafish model to study salt transport regulation. We plan to use the simple organization of the pronephros to establish a three dimensional model of the signaling proteins involved in regulating NCC activity. Work will be organized in collaboration with zebrafish specialists at the Max Delbrück Centrum (MDC) in Berlin. Specifically, we will,1. Analyze zebrafish NCC and NCC-like 2 expression, localization, phosphorylation, and activity2. Determine effects of NCC and NCC-like 2 knockdown3. Determine effects of WNK4 and OSR1 knockdown on NCC and NCC-like 24. Determine how distinct ion