RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'A New IACS Vision in Action' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The discussion on the modernisation of the Common Agricultural Policy (CAP) is in full progress and one element is how the CAP will benefit from and stimulate ongoing digitisation of the agricultural sector. Digitisation accelerates a cost-effective administration of CAP payments, the update of CAP instruments, stimulates data (re) use for monitoring the societal benefits of agriculture towards climate, environment and rural development and thus improves the sustainability and competitiveness of the sector. Administrative bodies from 9 EU Member States join forces to realise a new vision on the Integrated Administration and Control System (IACS) – the instrument for CAP governance – in this project called: “New IACS Vision in Action” (NIVA). The project is built on an iterative work plan. This ensures fast results, built-in flexibility and greater involvement of stakeholders. NIVA strives for maximum impact by involving all EU paying agencies and other relevant actors in the stakeholder board, by reserving a substantial budget for supporting third parties and the set-up of an innovation ecosystem that will continue after the project. NIVA manages cross cutting digital innovations as well as standardization issues in dedicated work packages as defining, accepting and defending common standards is exemplifying the desire for collaboration. The nine prime use cases are demonstrated in three waves, from national to multi-national to pan-European, hence underlining our ambition to make a significant contribution to improved digital competences, awareness and innovation at the European scale. The project’s results are a suite of digital innovations and a roadmap for IACS transformation. The project will speed up innovation, reduce administrative burden, sustain broader and de
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'A functional analysis of Listeria and Staphylococcus lipoteichoic acid' in the context of a Seventh Framework call.

assistant: **Objectives**

This proposal aims to provide insight into the physiological function of lipoteichoic acid (LTA) in the two Gram-positive bacterial pathogens Listeria monocytogenes and Staphylococcus aureus. LTA is an essential component of the envelope in Gram-positive bacteria. While the chemical structure of this polymer was elucidated several decades ago, the key genetic determinants for its synthesis have been identified only recently. These genetic studies made it clear that LTA has a crucial function within the cell, as absence of LTA severely impairs bacterial growth; a cell that lacks LTA has an aberrant cell shape and does not form normal division septa, but the molecular mechanism underlying these defects is not understood. With the recently developed mutants in the LTA synthesis pathway, we can now begin to address these questions. It is particularly intriguing that the absence of LTA on the outside of the cell influences the function and localization of FtsZ, the key cytoplasmic protein involved in the cell division process. However nothing is known about the molecular mechanism that links these two fundamental cellular processes.Upon consolidating my research group and with the experiments outlined in this application, I propose to investigate the molecular mechanism that links LTA synthesis with other fundamental cellular processes such as cell division and regulation of cell shape, provide insight into the structure and function of key enzymes involved in LTA synthesis, provide insight into the link between LTA synthesis and membrane lipid turnover and its functional consequences and determine the role of LTA as anchor for cell wall envelope proteins.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'European terrestrial ecosystem modelling activity' (1994-1998).

assistant: **Concept**

The goal of the project is to develop a comprehensive, process-oriented, modular modelling framework for the coupled dynamics of structure and function in natural and semi-natural ecosystems. This framework will allow simulation of ecosystems either at patch" (<0.1 km) scale or "regional" (10-100 km) scale, based either on species or on broad functional categories. It will link the following subsystems: - ecosystem-planetary boundary layer (PBL) interactions - ecosystem CO2 and H2O fluxes - vegetation physiology and phenology - biogeography and vegetation dynamics - detritus and soil organic matter (SOM) dynamics - human impact of naturalWe propose to develop a comprehensive modular modelling framework for the coupled dynamics of structure and function in natural and semi-natural ecosystems. The framework will link the following subsystems with widely varying time constants: ecosystem-planetary boundary layer ( PBL) interactions, ecosystem C02 and H20 fluxes, vegetation physiology and phenology, biogeography and vegetation dynamics, detritus and soil organic matter dynamics, and human impact and natural disturbance. The framework will allow simulation at "patch" scale, or at "regional" (10-100 km) scale including linkage of patches through the PBL. Comparative trials of modelling approaches to each subsystem will use the full range of available 0 observational and experimental data sources as evaluation tools. The coupled system dynamics will be tested with data from longterm field measurements and experimental programmes. A pilot study will show how the model can be generalised spatially, using gridded environmental data sets. The project is proposed as an integral component of TERI with close links to other TERI projects, in order to make best use of new data and mode
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Synthesis of Bio-based and Biodegradable polymers from monomers from renewable Biowastes via Biocatalysis and Green Chemistry to contribute to European Circular Bioeconomy' (Polymers-5B).

assistant: **Concept**

POLYMERS-5B aims to develop novel alternative biobased polymers synthesized from biobased monomers (diacids, diols, diamines, hydroxyacids, aminoacids, aromatic and phenolic compounds, fatty acids, oils, furans), sourced from underexploited second generation (2G) feedstocks such as agri/food waste (Tomato and Olive wastes) and biomass (wood pulp and lignin derivatives), obeying the food first and cascading principle. The project will resort to Biocatalysis and Green Chemistry processes to generate novel biobased polymers like polyesters and polyamides with pendent functional groups, (e.g., hydroxy, carboxylic, amine, epoxy, thiol, others), polyphenols and poly-furans, that mimic fossil-based polymers properties (e.g., polyethene terephthalate-PET, Polyurethanes-PUs, Acrylonitrile butadiene styrene-ABS, Amine and other polymeric resins), targeting improved biodegradability. These new polymers will be blended to provide valuable bio-composites and polymeric materials for the textile, automotive, furniture and polymeric resin markets. Machine Learning (ML) tools will drive the optimization of the developed technologies towards minimum resource usage “zero waste” and “zero pollution”, while technological, economic, and environmental sustainability aspects will be incorporated early in the design phase by adopting Sustainable by Design (SSbD) approaches. This sustainable strategy will contribute to an increase in the availability of monomers, bio-based polymers & plastic materials synthesized in the EU, that meet the Green Deal targets, reducing the carbon footprint and dependency on fossil-based raw materials and derivatives.


**Keywords:** Biocatalysis, Green Chemistry processes, Sustainable by Design, Machine Learning
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Electron and photon impact processes' to be submitted under Fourth Framework.

assistant: **Abstract**

Research objectives and content The past few years have seen an explosion of interest in the physics of (e,2e) and related processes largely thanks to support from the EU through the SCIENCEand HCM programmes. The object of this proposal is to allow one of the most successful of the recent Ph.D.'s in the field, (winner of the 1996 Ehrhardt prize), to move between two nodes of the existing HCM Network (CHRXCT930350) to acquire new skills and methods. We will jointly study more sophisticated ionisation processes than have been dealt with up to now. We will consider the ionisation of neutral atoms with particular reference to those processes where more than one target electrons are envolved. We will study: I. Excitation-ionisation i.e. processes where as a result of an electron impact one electron is ionised while a second bound electron is left in an excited state. II. (e,3e), two electrons are ionised by an electron impact III. (y,2e), photo-double ionisation IV.Compton processes e.g. (y,ey'), (y,2ey') Training content (objective, benefit and expected impact) The theoretical methods of the Metz group are entirely complementary to the Cambridge group from which the applicant comes. It is envisaged the applicant will be further trained in the latest computational and mathematical techniques and that these will be applied to a number of problems of genuine physical interest. Links with industry / industrial relevance (22) No direct industrial involvement is envisaged, but it is our belief that the research will be of value to European Industry in the long term.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'A novel biodegradable foam filled corrugated board of multiple thickness for the building, packaging and flat-pack industries.' to be submitted under Fifth Framework.

assistant: **Abstract**

An environmentally friendly novel biodegradable polyurethane foam-filled corrugated cardboard board is advanced as a replacement for MDF , chipboard, gypsum and polymer based boards. The proposed non-trivial processing route has considerable technical risk, has significant environmental benefits, and will use recycled waste paper and polyols derived from, for example rapeseed oils. The desired water blown foam, which currently does not exist in the market place, is a perceived R and D risk as the resin has to maintain sufficiently low viscosities to flow and fill the multiple channels and to expand and cure to yield a void free high strength structure. The engineering solution to deliver the foam has to address the changing physical parameters of the resin and is likely to involve development of vacuum and needle injection routes. The key benefits include lightness, strength, heat and sound insulating properties. The product adds value to recycled waste paper fibers and opens options to disposal via biodegradation routes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Marine life history strategies and biogeography: comparative study of the importance of benthic marine invertebrate early life history strategies in habitat connectivity for conservation management' (2002-2006).

assistant: **Concept**

The ability to effectively protect marine biodiversity is dependent upon an understanding of the connectivity between marine regions and appreciation of the mechanisms driving speciation. Larval biology, which differs significantly between marine invertebrates, is a driving force for structuring populations and habitat connectivity; knowledge of the patterns and influences of larval dispersal is important. However, genetic structuring of present day populations may also be a result of past events, such as changed current systems and coastlines during times of low sea level stands.This project will investigate the current paradigms describing the relationship between benthic marine invertebrate larval biology and their resultant biogeography and phylogeographic structure. Palaeogeographic and geotectonic factors will also be considered.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'A model to study how social interaction modulates sleep in the fruit fly Drosophila melanogaster' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Sleep is a fascinating phenomenon and one of the least understood mysteries of biology. It is universal among the animal kingdom and most species devote a large part of their day to sleep, despite the risks of lowering their defenses against predators or not engaging in more productive activities such as foraging or mating.In many animals, social interaction is a powerful modulator of sleep quality and quantity. In nature, animals are continuously exposed to a diverse variety of stimuli, and interactions with con-specifics represent a particularly relevant set of them. For Drosophila males, interaction with females is key to ensure reproduction, while interaction with other males can create antagonistic fights to compete for sexual partners, food or shelter. Through this project, I propose to investigate if and how social interactions affect sleep need and sleep quality. Employing fruit flies it has been previously shown that male-male interaction during the night builds up sleep pressure, observable in the next day as marked increase in sleep. Recovery of sleep after sleep deprivation is also called “sleep rebound”, and in all species it is thought to be 1) at the basis of sleep homeostasis and 2) positively correlate with sleep deprivation. The longer an animal stay awake, the higher the sleep pressure and following rebound. Also, it has been described that previous sleep experience modulates antagonistic behaviours between males. Thus, bidirectional interplay between social interaction and sleep appears as a promising framework to address a main goal of modern neuroscience, understand how sleep is regulated and which sleep functions are.I intend to use new developed behavioural paradigms and software that improve sleep analysis in combination with refined genetic too
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Approximation Methods for Molecular Modelling and Diagnosis Tools' to be submitted under Horizon 2020.

assistant: **Abstract**

This proposal brings together research teams from the EU (Germany, Italy, and Austria) and the Ukraine (Kyiv, Donezk) in the area of applied mathematics with emphasis on medical and life science applications. The goal is joint research in six research tasks concerning the study of mathematical methods for Magnetic Particle Imaging; entropy-like measures and quantification of system complexity; coarse-grain modelling for (bio)polymers; diagnostic tools for cardiac surgery; regularization methods for causality detection; meta-learning approach to Nocturnal Hypoglycemia prediction. Each such task will incorporate 24 months of research secondments (18 to the EU, 6 to UA).  Four project events (one per year), each including a scientific workshop, a training school and public outreach activities, are planned to be held in the Ukraine involving a total of 27 secondment months.  Senior scientists from Ukraine will have 15 secondment months targeted – apart from scientific and management work - at discussing issues how their institutions should develop in a restructuring of the Ukrainian research landscape.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Prospective cohort studies of children with substantial medical diagnostic exposure'.

assistant: **Concept**

The growing use of diagnostic X-rays and of high-dose techniques (CT, interventions) in children and adolescents is a topic of concern in radiological protection. Studies of other populations indicate that children are generally more sensitive to health effects of radiation than adults. In addition, children have a longer life-span to express any radiation-related health effect and, because of their smaller mass children, may receive higher doses to specific organs from these procedures if examination protocols are not adapted. Procedures of particular concern include: the use of CT in children (which delivers doses that are substantially greater than those from conventional X-rays); interventional cardiology, in which fluoroscopy is used to guide small instruments such as catheters through blood vessels (which, if repeated, can deliver doses of several hundred mGy to specific organs); and the use of repeated X-rays for monitoring respiratory, cardiac and digestive pathologies in premature babies (for repeated procedures, cumulative doses range up to a few mGy – and premature babies could be particularly sensitive to radiation induced diseases). Because the health effects of these low doses of radiation are expected to be relatively small, trans-national collaborative studies are needed to ensure sufficient statistical power to study these effects. In this project we seek support to assemble a critical mass of scientists involved in the study of medical radiation exposures and health effects of radiation dispersed throughout Europe with the aim of: ● Assessing the feasibility of establishing prospective trans-national cohorts suitable for long term follow up (including evaluation of the statistical power of the study) ● If the feasibility is demonstrated: - Making recom
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'American Trypanosomiasis Update' (ATU) under Sixth Framework.

assistant: **Objectives**

This project is designed to promote and facilitate the dissemination of results of excellently graded past and present programmes (ECLAT Network, CDIA Concerted Action; both jointly supported by EC, PAHO and local/national authorities) and to prepare future activities. It promotes collaboration in research, surveillance and control activities against Chagas disease and its triatomine bug vectors throughout the Americas. The activities include studying the behaviour of triatomine bugs, in support of Chagas disease vector control programmes throughout Latin America. Important focal points of the work are 1) to improve understanding of the evolutionary processes involved in adaptation of sylvatic species to colonise domestic environments, 2) to provide collaboration and support to congenital transmission and blood bank transfusion control programmes, and 3) to promote regional workshops intended to disseminate and discuss the implemented measures in the control of Chagas disease. In three analytical appraisals the re-colonization aspects will be considered. In the two workshops, one in the Andean and Central America/ Mexico region and another in the Southern Cone region groups of scientists from Europe and Latin America and  experts of control programmes and policy makers will exchange technologies and standardise criteria for control  interventions. The abstracts will be published.'
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Open Geometry PET, with 150ps TOF Resolution, for Real Time Molecular Imaging' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Open-IMAGING will develop an innovative Open Imaging System, highly flexible and adaptable to the organ to be examined. The system of the Proof of Concept will consist of two large paddle detectors built with the novel PET (Positron Emission Tomography) technology developed in 4D-PET ERC-ADG. Outstanding (<150ps) Coincidence Time Resolution and placing the detectors closer to the Field of View (FOV) will dramatically increase the sensitivity, allowing high resolution and high contrast images, at lower dose (factor 10) than current commercial scanners. It will open up new venues for real time image-guided interventions (surgery, radiation therapy) and in-vivo tracking of small number of cells. It will also enable performing repeated scans for active surveillance of suspect patients, diminishing the number of false positives, and a safer post-treatment (for instance, chemotherapy) follow-up.