RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'RISEWISE -RISE Women with disabilities In Social Engagement' (RISEWISE).

assistant: **Innovation**

Women with disabilities have more difficulties to find an employment and to integrate in social day life activities than men with disabilities.This project focuses on the collective of women with disabilities from different perspectives, trying to identify needs and best practices in several EU countries, representing different cultural and socio-economic environments, for the integration and improvement of their quality of life in several respects. By applying a novel analysis method, based on the experience acquired by the exchange of researchers, innovation staff and practitioners in the European area among the participating institutions, the project will identify a set of multi-sectorial research lines, to enhance integration and involvement of this population in the society along several dimensions.The delimitation of the scope of the project to this sector of the population has several advantages. First, it is the first relevant study at a global scale that is performed in Europe on this collective. Second, it allows putting into practice and validating a novel social research method, with a strong multidisciplinary approach, with such a well delimited case study. novel potential research lines can be explored in different settings to assess their opportunity and feasibility. Fourth, it will show the impact that this collective may have on a sustainable growth in economy and society, from different respects, by empowering their capacities, so far undervalued. Fifth, it will establish a platform for cooperation among research groups and associations in EU that are aware of the situation of this collective, looking for their synergies. It is worth mentioning that advances on technologies and measures towards a stronger social engagement of disabled people have final
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'VISible to far-IR optical tuning: passive DAYtime cooling by hierarchical structures and hybrid materials' (VISIRday) targeting Horizon 2020.

assistant: **Abstract**

Efficient daytime cooling without the need for a heat engine is an essential technology to lower our overall energy consumption. Nature offers a chance to off-load heat directly into the cold outer space via the so-called “sky window”: a spectral range from 8 – 13 µm, where our atmosphere is transparent. Concomitantly, solar radiance influx needs to be minimized by scattering and reflection, which would counteract the radiatively removed energy. VISIRday aims to provide ground-breaking new materials and concepts to emit thermal energy directly into this transparent sky window. A radically holistic approach is necessary to understand and design the optical properties of nano- and mesostructured materials over the entire spectral range (300 nm – 20 µm), with the mid-IR sky window being fully emissive, and all other spectral wavelengths being fully reflective. I will therefore combine top-down direct write lithography with intricate bottom-up colloidal self-assembly to device hierarchically structured systems fully addressing these stringent optical properties. A new material class – surface phonon polariton supporting nano- and mesoparticles – with adjustable absorption properties in the mid-IR range, will take a leading role as novel colloidal building block. In combination with polymers and metallic nanostructures my team will demonstrate hybrid structures with finely adjusted and even externally tuneable optical properties. Simulations based on finite element modelling to conceive optimum design rules will complement the experimental work. Inspired by examples from nature, namely white beetles and the Saharan silver ant, I will push the fundamental insights towards novel technologies such as radiative daytime cooling paints and fibres. I am convinced that this project
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Design of Nucleic Acid-Templated Ordered Protein Assemblies' under Horizon Europe.

assistant: **Concept**

Here I propose to create a new class of designed nanomaterials that will combine the advantageous features of protein design and DNA nanotechnology: nucleic acid-templated protein assemblies. I propose three different approaches that all utilize the addressability of nucleic acids on the nanometer to micrometer length scale to control size, shape, and composition of designed protein assemblies.In the first approach, the structural and mechanical properties of the assembly will be defined by the protein components, while the nucleic acid component serves merely to define the dimensions of the assembly and to introduce addressability to an otherwise symmetric, repetitive assembly. All components, including the nucleic acid template, can be genetically encoded, potentially enabling assembly of entire nanoparticles inside living cells.The second approach uses more complex nucleic acid templates, such as DNA or RNA nanostructures, to control size, shape, and addressability of two- or three-dimensional protein assemblies. The shape of the final protein assembly reflects the shape of the templating nucleic acid nanostructure, and the protein assembly can be viewed as a coating that adds rigidity, stability, and, crucially, biological functionality to the template nanostructure. Both approaches one and two are amenable to library-scale screening by coupling size and shape of the particles as well as patterning of functional domains (“phenotype”) to the sequence of the nucleic acid template (“genotype”).In a third approach, the nucleic acid is not incorporated into the final assembly, but merely serves as a “mold” to define size and composition of a protein assembly. A single DNA origami mold could thus “catalyze” the assembly of many nanoparticles, circumventing potential scala
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'DELIVERy of advanced therapies for diabetes training network' under Horizon 2020.

assistant: **Concept**

The DELIVER EID programme aims to equip 6 industrial PhD graduates with all of the tools required to become creative, entrepreneurial and innovative leaders in the emerging European advanced therapies sector. Advanced therapies are new medicinal products based on genes or cells and tissue engineering products (biomaterials), sometimes used in combination with medical devices. They herald revolutionary treatments for a number of chronic diseases including Alzheimer’s, cancer and the focus of the DELIVER programme, Diabetes Mellitus. We aim to DELIVER the next cohort of translational research scientists in the field of advanced therapies and enabling medical devices for pancreatic islet transplantation, a cell therapy which is poised to become more widespread for the treatment of insulin-dependent diabetes. The DELIVER doctoral training network therefore represents a major interdisciplinary effort between cell biologists, experts in biomaterials, medical devices and advanced drug delivery, clinical experts in islet transplantation and research-active biotech and biomedical companies. Each DELIVER early stage researcher (ESR) will tailor a Personal Career Development Plan (PCDP) to ensure that over the course of the programme the core research skills, advanced research skills and intersectoral transferable skills for a successful career in the advanced therapies sector are acquired. Intersectoral transferable skills training will focus on enhancing career opportunities and employability of the trainees by developing their innovative and entrepreneurial capacity, their communication and leadership skills and their commercial awareness. This will result in graduates with all the skills necessary to innovate, develop and translate advanced therapies for diabetes for the benef
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Micro-fluidic Biochips for trans-endothelial migration of eosinophils for the study of asthma' (ASTHMA).

assistant: **Concept**

Cellix Ltd., a spin-out instrumentation company from Trinity College Dublin, are experts in the area of nanotechnology and microfluidics having developed new and exciting microfluidic based technologies providing cell based assay solutions to advance basic science, medicine and drug discovery. The Academic partner is the Allergic and Asthmatic Inflammation group, School of Medicine, University of Aberdeen (UNIABDN) whose work focuses on the cells and mediators responsible for the initiation and resolution of inflammation in asthmatic and allergic disease.Asthma is now the most common chronic disease in westernised countries. It is a complex syndrome characterised by a variable degree of airway obstruction in which the fundamental abnormality is airway inflammation. One key area of ongoing work is furthering understanding of how an important pro-inflammatory effector cell in asthma, the eosinophil, selectively accumulates in the asthmatic lung. Central to this is an understanding of how eosinophils transmigrate from the blood vessels of the lung into the surrounding tissues where they exert their pro-inflammatory effects. This proposal combines proven expertise in leukocyte adhesion and transmigration (UA) with expertise in microflow adhesion of high throughput assays (Cellix).The development of the resulting platform technology will be used to identify therapeutic targets for asthma and to apply these novel technologies to other human diseases with a significant inflammatory component. By identifying those immunomodulators that facilitate/block adhesion and transmigration processes in an in vitro setting, prior to using an animal model, pharmaceutical companies would be able to remove/include such compounds from down-stream processing, thereby eliminating false leads ea
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Low-nox cost effective oil and gas combustion technology for glass furnaces, scaling by modelling and measurements by spectral sensors' (1994-1998).

assistant: **Innovation**

Objectives and content The European glass industry must now respect regulations designed to protect environment and resources. In France, 500 mg/Nm3 of NOx is a level that glass makers have considered as a target even though this level of emission is currently much below that which can be attained on regenerative glass furnaces (usually around 2500 mg/Nm3 when NOx are uncontrolled). The development and use of cost effective nonpolluting technologies to bum current fuels and to support operators of large regenerative glass furnaces is considered in the proposal with the ultimate objective to promote for the clean environment in Europe. Such furnaces represent 90% of glass production in Europe and are oil or gas fuelled (50% oil and 50% gas). The objective of the project consists in reducing the NOx formation within glass furnaces by primary measures i.e by enhancing the burner system technology instead of carrying out secondary measures that may be used to suppress the NOx after NOx formation, such as denitrification by ammonia reduction or reburning. The economic cost of secondary measures (e.g. for selective catalytic reduction) can be evaluated to 2,5 ECU/ton of glass to be compared with a mere 0,022 ECU/ton of glass for the solution to be developed within the project. New burner systems including a new low-NOx smart regulating element will be developed in order to limit the amount of NOx formed during combustion. The scientific and technical approach will encompass 3 scales in a stepwise manner: Laboratory scale (200 kW), semi-industrial scale (0,5 to 2 MW), industrial scale (15 MW). The interpretation of the NOx formation phenomena and the burner scaling up will be ensured by modelling. New imaging sensors will be developed to provide data for the control of burner
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Selective fluorinated inhibitors of matrix metalloproteinases 3 and 9' (1998-2002).

assistant: **Concept**

Heart failure and cancer are the two major causes of death in developed countries. Current therapies for their cure are affected by largely unsolved problems. A common feature of both pathologies is that matrix metalloproteinases (MMPs) 3 and 9, which are zinc-dependent proteolytic enzymes, play a key role. Inhibition of MMPs 3 and 9 is promising for heart failure and cancer therapy, but the currently available inhibitors are poorly selective, and therefore toxic. The primary objective of this project is to discover novel families of inhibitors selective for MMPs 3 and 9 from fluorinated peptidomimetic units. This challenging goal will be pursued by exploiting the potent tools made available by a synergistic and multisciplinary collaboration encompassing all aspects of drug discovery, including fluorine/asymmetric/combinatorial chemistry, structural chemistry, modeling, protein crystallography, pharmacology, physiology and biology, with the additional support of an industrial partner. The other main objective of this research project is to provide an effective training for young scientists at the interface of chemistry and biology in a very competitive international context where discovery of new drugs rests mainly on the ability to use complementary approaches from various disciplines and expertises. Eventually, the scientific achievements stemming from this project will improve our knowledge of a variety of timely and fundamental topics such as(1) the asymmetric/combinatorial synthesis of chiral fluorinated peptides and mimetics,(2) the mechanism of action of MMPs,(3) the behavior of fluorine-containing functions in the enzyme active sites, as well as of their influence on the recognition of the ligand by the enzymes and the effect on the binding affinity,(4) the in v
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Reforming health services in urban china : dissemination of research findings' (1998-2002).

assistant: **Concept**

This study found that certain vulnerable groups had serious problems getting access to health services. Also, hospitals waste substantial resources and their efficiency is falling. These findings were presented to a workshop attended by national policy-makers, officials from the study cities, senior researchers and officials of international donors. Both city officials and national decision-makers expressed a need for health development strategies to address these problems. But, they stressed the need for intensive efforts to gain a wider understanding of proposed new approaches. The workshop identified the following objectives for a dissemination strategy:- contribute to Chinese debates about urban health reform- strengthen contacts between national policy-makers, city officials, researchers- disseminate the methodology to the Chinese research community- increase international understanding of urban health reform in China
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Pan-Ideologies in Central Europe: Paradoxes of Right-Wing Self-Orientalism.' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The rise of right-wing populism in Central Europe coincides with the revival of pan-ideologies. Cases of Turanism promoted by the ruling party in Hungary and Pan-Slavism popular among right-wing activists in Slovakia pose a need to study these intellectual projects simultaneously in comparative and historical perspectives. The common feature of these competing traditions is a contradictory combination of racism and self-orientalism. Adepts of Turanism and Pan-Slavism often define themselves as belonging to a non-European race and simultaneously sympathize with typical far-right consensus on white supremacy. Why are pan-ideologies rooted in outdated pseudo-scientific theories so popular among right-wing populists of Central Europe today? To answer this question, we need to conduct a multidisciplinary study combining social anthropology and history. The proposed project aims to understand how modern adaptations of pan-ideologies differ from the original versions popular in the first half of the 20th century; and how these transformations correlate with the aims and resources (such as access to state institutions) of the ideologues. The novelty of the research project includes the suggestion to look at right-wing ideologies as phenomena embedded in the colonial and postcolonial history of the region. I propose to study Turanism and Pan-Slavism as products of contact zones, co-evolving and constantly influencing each other and affected by overlapping colonial regimes and postcolonial conditions. Following the guidelines of the Horizon Europe Programme to support social cohesion and inclusiveness, we need to conduct a focussed study of processes of polarization. The research project aims to explain how pan-ideologies attract new followers and why they are becoming popular ag
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'FUNctional-structural plant models for improved estimation of crop and soil status based on REmote Sensing Observations' under Seventh Framework.

assistant: **Concept**

The present proposal aims at developing a novel approach for improving the accuracy of estimation of crop and soil variables from remote sensing, which is today limiting for a number of applications as in precision agriculture.  The approach is based on the coupling of a dynamic functional crop model to a 3-D canopy structure model. This will allow to take explicitly into account the 3-D architecture of plants while including the effects of water and nitrogen stress and to assimilate directly the reflectance data into the 4-D (3-D plus time) model. Improvements in remote sensing information retrieval accuracy are expected by a) implicit and explicit inclusion of prior knowledge of vegetation parameters, allowing attenuation of problems due to the ill-posed nature of information retrieval from remote sensing and b) better accuracy of canopy reflectance simulations due to the improved realism of such models as compared to classical turbid medium approaches. The research work will be carried out at one of the leading research groups in the world in this sector, the INRA CSE Unit in Avignon (France), and will take advantage of the existing functional structural 4-D models available at the host institution as well as model inversion procedures and experimental results and databases developed by the CSE team.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Population Codes for Space in the Mammalian Cortex'.

assistant: **Concept**

A major goal in neuroscience is to understand neural computation in the mammalian cortex. Since the 1950s, we have learnt how cells respond to changes in the environment but the cells have largely been observed one at a time. However, single-cell recording cannot access the complexity of distributed processing and coding in the large, intermixed cell populations of the cortex. To understand this complexity, we need population-wide activity measurements, at single-cell resolution, as well as theoretical models to interpret the data.  In this project, we shall combine experiments and theory to enable a paradigmatic shift from single-cell to population analysis for a prototypical high-level cortical system, the navigation system of the mammalian medial entorhinal-hippocampal region. In this system, spatial firing correlates of individual cells are so evident that they have been given simple, descriptive names – such as place cells, grid cells, and head direction cells. The wealth of information on the phenomenology of these cells, and the existence of theoretical frameworks that offer strong predictions on their population-wide activity patterns, renders the system perfect for population-level analyses of cortical computation. We shall introduce experimental tools to obtain the amount and specificity of multi-neuron data required to decipher neural population codes in freely navigating rodents. Guided initially by theory on attractor network dynamics, we shall identify regularities in firing and connectivity patterns of thousands of simultaneously monitored neurons and use the data to test, refine and develop theoretical models. This exercise will be extended to less-understood high-end systems such as lateral entorhinal cortex, where computational operations have remained