RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'System for the efficient and non-invasive harvesting and RElease of ADherent CELLs controlled by light' (READCELL) targeting Horizon 2020.

assistant: **Abstract**

The Biopharmaceuticals market is currently valued at about 150,000 million euros with an annual growth rate of 6 %. Biopharmaceutical products are mainly obtained from cells cultured in contained systems. Adherent cells represent an important share of the cell types used in production processes and are the major source of cell therapy products. Productivity of current processes for adherent cells culture lags behind those based on suspension cells and the reasons for this imbalance are to be found mainly on the low volumetric productivity and automation of current processes for adherent cells culture. Recovery of cells from the surface they are attached to, the so-called cell harvest is commonly performed by disrupting the interaction of the cells with the support by manually introducing hydrolyzing enzymes into the culture device. These enzymes attack the cell at the adhesion point driving them into suspension for further recovery. Due to the manual nature of the cell harvest step, the exposure of cells to the external environment during the enzymatic treatment and the harsh biochemical conditions, this is one of the least efficient steps in the production process and poses an important risk of damaging and contaminating the culture. The idea proposed in this project for Proof of Concept will turn the cell harvest step into an automated, non-invasive and efficient step in the cell culture process. To achieve this goal we will introduce nanostructured modifications in the cell culture support by immobilising gold nanoparticles of defined size and shape, in certain geometrical patterns. The resulting cell culture support interacts with low energy electromagnetic radiation coming from an external and non-invasive source, creating localised hyperthermal effects at the loca
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Enabling mass access to the social phenomenon of e-sports tournaments by integrating In-Game Platform in world’s leading video games'.

assistant: **Innovation**

A new universe of video game tournament (called e-sports) has transformed dramatically the video game industry over the last two years. However, organising and participating in e-sports tournaments remain complicated for players and publishers. OXENT wants to support and amplify this massive growth of e-sports by integrating an e-sports platform directly in top selling video games (so-called in-game approach). The current state-of-the-art reveals that no in-game tournament solution exists. With its innovation, OXENT wants to change the way video games are played, with a massive shift towards tournaments among the average player. OXENT aims to become the world leader of e-sports tournament technology with € 34 million income in 2017 and 20 employees.Our BtoBtoC solution meets the needs of both players and of publishers. Direct integration into video games democratises the use for players, by giving access to the platform automatically and intuitively. Publishers will easily shift from single sales business model to subscription. Therefore, client retention will increase, and the games life cycle will be extended. In addition, new sources of revenue will be created through tournament fees. The feasibility study will assess three key levels:1. Technical: Test in-game performance and improve design and ergonomics.2. Economic: Define the business model through meetings with global publishers and potential business partners3. Legal: Identify data collection legal issues and the opportunity to protect our knowledge.For global commercialisation of our innovation, total funding requirement during 2 years for Phase 2 is estimated at € 2 800 000.The dissemination of the innovation will be global. For cultural and market size reasons, target geographies for video game players inclu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'European-COMPARative Effectiveness research on online Depression' (E-COMPARED) targeting Seventh Framework.

assistant: **Abstract**

In 2010, 30 million Europeans were affected by depression and their number is still growing. Half of Europeans in need of mental care for depression do not have access to care services, do not always receive evidence-based treatments, are confronted with long waiting lists or high care expenditures. Internet-based treatment has the potential to addresses the drawbacks of standard care and keep depression treatment of high quality and affordable. E-COMPARED will conduct comparative effectiveness research in routine specialized mental care settings on the (cost-) effectiveness of internet-based treatment for depression in comparison with standard care. Health care systems, and -policies, existing ICT infrastructures and their uptake will be taken into account. E-COMPARED aims to 1)Evaluate EU mental health policies/guidelines for standard and internet-based care for depression in specialized care settings in countries with different health care systems and access levels of standard and internet-based care; 2)Compare clinical efficacy and cost-effectiveness of internet-based treatment and treatment as usual within controlled research settings, 3)Carry out pragmatic randomized controlled trials to study how internet-based depression treatment can be effectively implemented within routine specialized care settings, 4)Predict which patient groups could benefit from internet-based treatment vs. standard treatment by modeling patient characteristics; 5)Develop evidence based recommendations on how internet-based depression treatment can be cost-effectively integrated into routine specialized care systems for depression in EU mental health care systems, and develop a business case to ensure structural implementation of these services. E-COMPARED is multidisciplinary (psychology,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Wind early alarm system for terrestrial transport handling evaluation of risks' in the context of a Sixth Framework call.

assistant: **Objectives**

Over the years the effects of high winds on road and rail vehicles have become of increasing concern to transportation system operators. Cars, high-sided lorries and trains can be at risk of a wind-induced accident on exposed sites such as embankments or long span bridges. The objective of the proposed Craft WEATHER" is to develop an innovative wind alarm system for terrestrial transportation, which will enable risk evaluation. The WEATHER system will predict both the wind and the risk for a road transportation vehicle, taking into account the real ground configuration.The aim of the project is to improve the safety of ground vehicles, specifically rail and road vehicles when exposed to strong high winds: WEATHER expected innovative achievements are the following: - To elaborate spatial-time wind models (including prediction models) in compliance with the needs of wind alarm systems (Workpackage 1)."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Development of the optimum AGRAL cermet manufacturing process for aluminium inert anode application and fuel cell interconnect plates.' in the context of a Horizon 2020 call.

assistant: **Objectives**

The AGRAL (Advanced Green Aluminium anode) project will aim at developing the manufacturing technologies of a specific cermet (called AGRAL cermet within this proposal) that has shown at lab scale outstanding properties in high temperature and corrosive media i.e. aluminium electrolysis. Furthermore, this AGRAL cermet enables Aluminium Pechiney, leader of this project, to consider the replacement of their current carbon anode by this inert anode thus decreasing to zero the CO2 emission during electrolysis process. Furthermore this AGRAL cermet will be tested for two applications: aluminium electrolysis (for the manufacturing of an inert anode up to industrial scale) and for protection of interconnect plates in hydrogen and fuel cell application (up to pre-prototype scale). This AGRAL cermet will be used as an inert anode in the Aluminium industry. Thanks to the inert anode, it is expected to decrease by a minimum of 50% of CO2 emissions compared to currently used carbon anode. Then, the transfer to the fuel and hydrogen cell applications will be studied.To reach the objectives, the partners will aim at:- Developing the manufacturing process for the AGRAL cermet coating for aluminium electrolysis  o The Thermal Spray coatings: HVOF (combined eventually with Cold Spray ) and eGun (HVOF with ethanol, technology developed by Flame Spray Technologies)o The Powder Metallurgy Process : HIP and Ultraflex (technology developed by Kennametal Stellite)The final manufacturing process will be adapted to large dimension (an anode is 1m long) and to complex shape (plates, grid).- Developing qualification test for real scale inert anode to detect failure of the anode operation- Developing the manufacturing process for the AGRAL cermet coating for hydrogen and fuel cell interconnect pla
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Autonomous Sampling with Robotics in the Wild for Nature Conservation' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The need for effective, cost-efficient conservation practices is greater than ever as we are now facing catastrophic loss of Earth’s biodiversity. Current conservation practices, from sample collection to inspection and monitoring, are typically very labour intensive, costly and time-consuming. Collected data are often inaccurate, incomplete or subject to human bias. However, recent advances in robotics and Artificial Intelligence (AI) technologies have shown a great potential for offering practical tools for conservationists. Therefore, the aim of WildBotics is to boost ecosystem conservation practices through innovation in robotics, sensors and AI solutions. Autonomous terrestrial, aquatic, and aerial robots will be used as a unifying platform to elevate the ongoing digital revolution of nature conservation practices and integrate leading-edge conservation ecology and computer science. WildBotics will develop new autonomous long-endurance systems, improve current sensor and software capabilities and combine these advances to create practical solutions for large-scale automated monitoring or collection of samples, thus supporting cutting-edge conservation research. WildBotics will expand current computer vision capabilities in ecology, create practical solutions for monitoring wildlife populations and ecosystems, and offer effective and automated means of gathering and interpreting samples. These challenges will be solved by 12 PhD candidates hosted in 12 recognized and interdisciplinary organizations. A multifaceted research training programme has been designed to educate a new generation of PhDs and provide them with a unique skill set enabling them to tackle the great challenges we face to mitigate the decline of global biodiversity. WildBotics will raise the level
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Improved fallows by legume plants (trees, shrubs and grasses) in eastern and southern africa. impact of soil biota (som, roots, bnf microbes, mycorrhiza, and soil fauna) improvement on bean and maize yields, soil organics matter dynamics an' (IMPALA) under Fifth Framework.

assistant: **Objectives**

The impact of short-term improved fallows (IF) by legumes (trees, shrubs, grasses) on maize and beans yields and soil properties will be assessed to counteract declining staple food production in nutrient depleted soils in Eastern and Southern Africa. In a novel approach these agro forestry practices will be associated with no- or minimum tillage (NT) to enhance the beneficial effects. The project will increase understanding of the underlying biological (N2 fixation, mycorrhiza, soil fauna) and physical (aggregation, infiltration, erosion) soil processes in IF/NT systems and evaluate how the positive effects can be maximised. Wider environmental benefits (C sequestration, erosion reduction) of adoption off/NT will be assessed using modeling approaches. The socio-economic environment required for the widespread adoption of IF/NT will be evaluated. The project will be carried out in Kenya, Zambia and Zimbabwe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Artificial Intelligence techniques for ice core analyses' under Horizon 2020.

assistant: **Concept**

The detection of insoluble particles trapped in ice or sediment cores, like pollen grains, foraminiferal and diatom assemblages, volcanic and dust particles represents the basis for paleoresearch on the biosphere, volcanism and oceanic and atmospheric realms. To date, except for ice core dust, this analytical goal is achieved during years of particle observations by manual microscopy. Artificial Intelligence predictive models are already applied to several research fields within geoscience, but up to date its implementation to paleoclimate is missing. With ICELEARNING, I aim to develop a two-phase routine for the automatic quantification of insoluble particles trapped in ice cores. The routine is based on a commercial Flow Imaging Microscope producing particle images from within melted ice samples. The images are then analyzed by Pattern Recognition algorithms which will be developed for automatic particle classification and counting. The routine will be specifically developed in order to be implemented in Continuous Flow Analysis (CFA) systems, therefore surpassing the traditional methods by providing continuous particle records from ice cores. ICELEARNING methodology is suitable to any diluted sample, thus representing a ground-breaking analytical advancement from ice core science to marine geology. This innovative routine is automatic and non-destructive, imperative prerequisites for the future Antarctic ice core project analytical measurements, aiming to retrieve a continuous climatic and environmental record covering the last 1.5 Myr. ICELERNING will be developed at Ca’ Foscari University of Venice with Prof. Carlo Barbante, leading expert in trace and ultra-trace level impurity detections in ice cores and with the University of Bergen, a top institution in marine
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Does population size structure affect larval viability in marine fish? Insights into maternal investment using stable isotopes' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

One of the most pervasive effects of decade long overexploitation of marine fish is the truncation of size distributions in affected populations. Today, many populations of commercially important species, such as Atlantic cod (Gadus morhua), consist of smaller individuals than just a few decades ago. Concurrently, a general decline in recruitment has been observed with severe consequences for population growth and productivity. These observations have led to the formulation of the Big Old Fat Fecund Females (BOFFF) hypothesis, which states that older, larger females contribute disproportionally more to the recruitment because of their increased mass-specific fecundity and production of more viable offspring. The first part of the hypothesis has been tested and confirmed, while the considerably more challenging test of superior offspring survival is hindered by the inability to link individual offspring caught in the open sea to the size of the mother. In the POPULAV project, I will use size-specific natural biochemical markers (stable isotopes) to link maternal size to larval viability. Larvae are provisioned with the maternal isotopic signature via nutrient transfer from maternal gonads to the eggs/larvae; A promising, novel tool to provide a robust test of the BOFFF hypothesis. The objectives are to (1) confirm the size-effect on maternal gonadal isotopic signature, (2) assess size-dependent stable isotope transfer in laboratory experiments, (3) assign wild-caught larvae to the size of its mother using stable isotope profiles, and (4) use a simple model to estimate the effect of population size truncation on larval viability. Data obtained in POPULAV will advance our understanding of how size truncation  affects larval viability and thereby recruitment. This knowledge
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'ONCOWORM: Using functional genomics in highly regenerative flatworms to find novel cancer genes'.

assistant: **Concept**

This project will take direct action in exploiting the powerful planarian model system to achieve novel insights into the molecular processes underpinning oncogenesis and cancer. Based on the principle that biochemical and physiological functions of many genes are conserved across phyla we will identify planarian genes that control the migration, proliferation and differentiation of the highly proliferative pluripotent adult stem cells (pASCs). We will combine a bespoke specially designed partial irradiation assay, bioinformatic and expression based candidate gene identification and the capacity to perform RNAi based screens of gene function to identify novel genes controlling pASCs that are conserved in humans. Those novel genes of greatest promise will then be studied in mammalian cancer cell lines using the insight gleaned from planarians. This project brings together, for the first time, a world-class planarian laboratory with an eminent cancer cell biologist, Dr Kosaka, who will acquire all the expertise required to exploit the planarian system and at the same time transfer his extensive knowledge of cancer biology to the Aboobaker laboratory.


**Keywords:** Evolution, multicellular organisms, origin of cancer, cancer initiation, high-throughput screening, over-proliferation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Oxidative Coupling of Methane followed by Oligomerization to Liquids'.

assistant: **Objectives**

The general objectives of the OCMOL project, focussed on the development of an alternative chemical route based on oxidative coupling of methane followed by oligomerization to liquids, are twofold: 1. To develop a small-scale process: process intensification via cutting-edge micro reactor technologies will enable to skip the expensive scaling up stage to provide a proof of concept of the OCMOL liquefaction route  for companies to make go/ no go decisions. 2. To develop a fully integrated process, which will be self-sufficient through the re-use and the recycling of by-products at every process stages. Such an innovative route offers 4 main advantages: 1. An economic operation at capacities of 100 kT/year, which is nowadays not possible by using state of the art technologies. 2. An operation at more uniform pressure levels 3. The flexibility of product streams  4. Low if not zero CO2 emission thus contributing to face global warming. The OCMOL route to convert natural gas into liquid fuel will encompass methane oxidative coupling, methane dry reforming, membrane/PSA separation and  oligomerization. Process intensification, such as the integration between methane oxidative coupling reactor, dry reforming reactor, and membranes integration will be one of the main challenges addressed to improve the energy efficiency of the whole process. A strong focus will be put on cutting-edge material science to develop effective catalysts/membranes which are of paramount importance to implement the innovative processes foreseen. Moreover, micro reactor technologies will be adopted to investigate novel reactor designs necessary to ensure the efficiency and the cost-effectiveness of the OCMOL solution.