RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Holistic Integration of Emerging Supercomputing Technologies' (Hi-EST) targeting Horizon 2020.

assistant: **Abstract**

Hi-EST aims to address a new class of placement problem, a challenge for computational sciences that consists in mapping workloads on top of hardware resources with the goal to maximise the performance of workloads and the utilization of resources. The objective of the placement problem is to perform a more efficient management of the computing infrastructure by continuously adjusting the number and type of resources allocated to each workload. Placement, in this context, is well known for being NP-hard, and resembles the multi-dimensional knapsack problem. Heuristics have been used in the past for different domains, providing vertical solutions that cannot be generalised. When the workload mix is heterogeneous and the infrastructure hybrid, the problem becomes even more challenging. This is the problem that Hi-EST plans to address. The approach followed will build on top of four research pillars: supervised learning of the placement properties, placement algorithms for tasks, placement algorithms for data, and software defined environments for placement enforcement.Hi-EST plans to advance research frontiers in four different areas: 1) Adaptive Learning Algorithms: by proposing the first known use of Deep Learning techniques for guiding task and data placement decisions; 2) Task Placement: by proposing the first known algorithm to map heterogeneous sets of tasks on top of systems enabled with Active Storage capabilities, and by extending unifying performance models for heterogeneous workloads to cover and unprecedented number of workload types; 3) Data Placement: by proposing the first known algorithm used to map data on top of heterogeneous sets of key/value stores connected to Active Storage technologies; and 4) Software Defined Environments (SDE): by extending SDE de
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Intermittent processes in rivers: surrogates for assessing the impact of global change on estuarine-coastal contaminant fluxes' under Fourth Framework.

assistant: **Concept**

RTD actions implementing ENRICH are part of accompanying measures of the Environment and Climate Programme, the Marine Science and Technology Programme and the International Cooperation Programme. CORDIS generally does not held information on accompanying measures of RTD programmes. Therefore for further details please contact: Ib Troen, European Commission, DGXII.D.I at ib.troen@ec.europa.eu.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'POLYmer based electro-optic PCB motherboard integration with Si3N4 Chiplets, InP Components and Electronic ICs enabling affordable photonic modules for THz Sensing and quantum computing applications' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Despite the significant advances that photonic integrated circuits (PICs) offer in terms of miniaturization, power consumption and functionalities, they run into scalability and cost issues, related to the fabrication yield, the increased integration and packaging complexity, the lack of wafer scale compatible processes and the lack of integration and packaging standards. Furthermore, so far photonic packaging considered the sub-GHz electrical connections to the PICs as a separate and second priority issue, until the number of electrical IOs of the PICs was too large to ignore. POLYNICES aims to address these challenges with the development of a novel general purpose photonic integration technology, compatible with wafer scale processes that will reduce the production costs of photonic modules by at least 10x. POLYNICES will develop for the first time a polymer based Electro-Optic PCB (EOPCB) motherboard that will host Si3N4 chiplets, InP components and micro-optical elements. POLYNICES invests in Si3N4 platform with PZT actuators to realize complex structures in only 1x1 cm2 chiplets with ultra-low power consumption. The chiplets’ grid array electrical pads and the use of flip-chip integration on vertical alignment stops will allow optical alignment and electrical connection in one step. The standard size and interfaces of the chiplets as well as the electronic IC co-packaging on the same EOPCB, provides excellent scalability and customization, and significantly simplifies packaging. Dielectric rod THz antennas will be integrated on the EOPCB taking advantage of its good HF properties. Using the above novel concepts and building blocks, POLYNICES will develop a fully integrated optoelectronic FMCW THz spectrometer with THz antenna array and beam steering abilities for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'HydrogEn Lightweight & Innovative tank for zerO-emisSion aircraft' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

To enable a technologically and economically feasible H2-powered aviation, new integral LH2 tank solutions are required that could serve as part of the airframe main structure and capable of withstanding its respective loads. The H2ELIOS project will develop an innovative and effective lightweight LH2 storage system for aircraft. It will be implemented as demonstrators in two fuselage-like cylinder section with approximately 1.9 m of external diameter and approximately 2.3 m of external length. These demonstrators would be duly supported by component and subsystem ground tests at appropriate scale at project completion (TRL 5 at storage level). The aim is that the concept is ready to be embedded and integrated in a specified aircraft architecture for flight demonstration in later stages. H2ELIOS will provide a feasible and novel low-pressure double-layer composite tank-based system, enabling the tank shape to be either conformal or non-conformal to the profile of the aircraft. Its general effectiveness will be assessed in terms of high GI performance and easiness of integration within the aircraft structure.This concept will be supported by latest evolutions of innovative methods and technologies in terms of multidisciplinary design development, manufacturing processes and means of compliance and shall be demonstrated in operational conditions: first on ground up to TRL5 and then in flight by the end of Clean Aviation Phase 2 clearing a TRL6 maturation gate. Finally, delivery to the market is expected in the 2030-2035 period. In this way this project shall contribute to accomplish the objectives of the European Green Deal regarding decarbonization of the aviation industry.The activities of H2ELIOS will be supported by explicit agreed support of EASA and an External Advi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'High-Precision micro-forming of complex 3D parts'.

assistant: **Innovation**

Today, Europe’s leading position in manufacturing of formed, high-precision 3D metal parts is being threatened by developed non-EU countries that catch up quickly on product quality at low cost. If no further action is taken, loss of jobs and GDP are at risk. To face global competition, a breakthrough is needed in tackling the following four challenges: - Continuous product trend for higher quality, smaller features, at simultaneous demand for lower cost price; - Reduced number of finishing operations and consumption of raw materials and energy; - Reduction of machine downtime; - On-line 100% quality control of 3D complex shapes. HiPr will realise this essential breakthrough. The primary goal of HiPr is to develop and integrate all necessary base technologies which create the basis to control and monitor the condition of micro-tooling for complex high-precision 3D parts. This will be achieved by developing and integrating: in-depth process and material knowledge, in-line measurements, real-time predictive maintenance.Proof will be given on pilot production lines in industrial settings.  HiPr will do this with a consortium of partners best-in-class in these fields. The methodology that will be used to come to efficient realisation is the following: Define and describe the process, measure tool performance, model based prediction of tool performance. This methodology will result in reduction of:  - cost by >20%; - material and energy consumption by >30%; - development cost reduction >30%. The knowledge-based HiPr results are also applicable in different sectors, leading to low defects, despite customisation trends. HiPr will therefore help in assuring a competitive and sustainable European manufacturing industry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Bitrate flexible code division multiplex for atm access' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Main ObjectiveThe main objective of FLEXIMACS is to investigate and develop a synchronous code division multiple access (S-CDMA) technique, which allows flexible bitrate assignment and quality of service for the individual user in an ATM based multipoint to point access network supporting both high capacitance and high robustness against interference and noise. The project will identify applicable S-CDMA flexibilization schemes and investigate appropriate solutions for the minimisation of multiple access interference (MAI) and for media access control (MAC) protocols regarding their efficiency, delay and flexibility. Based on the identified and defined alternative approaches and algorithms, a preferred overall system solution will be selected in terms of granularity, complexity, flexibility, performance and cost. Technical ApproachBroadband access systems of the immediate future will have to use existing wired networks, such as cable television (CATV) networks, or emerging wireless techniques, e.g. microwave and mm-wave radio, to bridge the last mile to the user and offer rapid, flexible and economical access to new services. ATM is an appropriate transport technique to integrate services of different bitrate and quality requirements onto a single digital access link and to provide interoperability of technologies as different as wireline and wireless final drop on a single access node.An access system with a shared medium, such as a hybrid fiber coax (HFC) cluster or a radio cell, needs a multiple access scheme in the upstream direction to manage the traffic of a number of simultaneous users. Frequency Division Multiple Access (FDMA), Time Division Multiple Access (TDMA) and Code Division Multiple Access (CDMA) as well as hybrids of these are being considered. Both fre
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Nanoengineering High-Performance Low-Cost Perovskite Solar Cells Utilising Singlet Fission Materials' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

This project aims to combine two recent breakthroughs in solution-processed thin-film solar photovoltaics (PVs) to demonstrate a low-cost, stable PV device with an efficiency approaching conventional crystalline silicon devices. The aim will be achieved by integrating singlet fission, a process capable of pushing PV efficiencies beyond conventional limits, with recent exciting perovskite results. The researcher is uniquely suited to this ambitious project, which will engage him with world-leading techniques, collaborations, and transferrable skills and help him to achieve his goal of establishing a leading UK-based device spectroscopy research group.The project comprises an outgoing phase in Prof. Valdimir Bulovic’s Organic & Nanostructured Electronics Group at the Massachusetts Institute of Technology, where their unrivalled expertise in the deposition and nanopatterning of materials will be applied to perovskite/singlet fission devices. This expertise will be transferred back to Prof. Sir Richard Friend’s Optoelectronics (OE) Group at Cambridge University, world-leaders in ultrafast spectroscopy. Device behaviour will be elucidated and performance optimised by studying ultrafast phenomena such as the dynamics and mechanism of charge generation. Such a partnership of high-end nanoengineering and ultrafast spectroscopy is yet to be achieved and is likely to lead to revolutionary breakthroughs.The work will ensure that state-of-the-art expertise not currently available in the European Research Area (ERA) is transferred to the European community. This will create strong international links between the two leading groups, with enormous potential for intellectual property generation and industry involvement through OE Group spin-outs and partners and knowledge transfer from
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Microcrystallography of stabilized adrenergic receptors' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

Nowadays microfocus beamlines at intense and brilliant synchrotron radiation sources allow studies of samples with low X-ray scattering power to be curried out with new micro-methods. Structural information of excellent quality can be produced for proteins, which crystallize yielding only tiny crystals. The structure of recombinant rhodopsin obtained recently in host laboratory is an example of successful microcrystallography application. Several other membrane proteins from the GPCR family were studied in host laboratory for many years among them adrenergic receptors. Recently microcrystals of beta-adrenergic receptor were obtained in host laboratory and structure solution efforts were initiated. The corresponding strategy for structure solution of beta-adrenergic receptor is proposed here. New approaches to data collection from microcrystals including scanning microdiffraction and random data collection will be developed for successful structure determination. Application of micron and sub-micron beams for data collection will be assessed. Additionally, development of the software dedicated for reduction of data from microcrystals is suggested. Efforts in advancing microcrystallography will result in obtaining a high-resolution structure of beta-adrenergic receptor, which will help to rational drug design and will give new insights on GPCR signalling mechanism.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Enzyme-integrated high-throughput Multicomponent synthesis for Echo-enabled Rapid molecule generation and Assay in Lead Discovery' (EMERALD), addressing dissemination and exploitation.

assistant: **Impact**

Indoles are among the most widely encountered scaffolds in medicines and natural products, yet general strategies for their systematic diversification remain limited. Through EMERALD (Enzyme-integrated high-throughput Multicomponent synthesis for Echo enabled Rapid molecule generation and Assay in Lead Discovery), I will unites three complementary techniques into the first miniaturized, automated pipeline for late-stage indole diversification at nanoliter scale (i) multicomponent reactions for efficient and modular assembly of indole frameworks; (ii) enzymatic tailoring, enabling regio- and chemoselective functionalization; and (iii) acoustic droplet ejection combined with real-time mass spectrometry, delivering ultra-high throughput synthesis and analytics with >90% reductions in solvent use. During a secondment at the University of St Andrews, I will evaluate enzyme panels to produce compatibility and selectivity maps directly relevant to drug discovery. Importantly, a subset of the resulting functionalized indoles will be screened against the p53–MDM2 interaction, a clinically validated target in oncology, to demonstrate the platforms’ direct translational potential. By marrying chemical and enzymatic methodologies, EMERALD establishes a sustainable route to novel scaffolds and natural product–inspired analogues, while providing an ideal interdisciplinary training ground at the interface of chemistry, biocatalysis, and automation-ultimately advancing greener drug discovery and fostering my path to research independence.


**Keywords:** Indole scaffolds - multicomponent reactions - enzyme catalysis - acoustic droplet ejection -  high-throughput screening
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Unlocking unused bio-WASTE resources with loW cost cleAning and Thermal inTegration with Solid oxide fuel cells' (WASTE2WATTS).

assistant: **Innovation**

WASTE2WATTS (W2W) will design and engineer an integrated biogas-Solid Oxide Fuel Cell combined heat and power system with minimal gas pre-processing, focusing on low-cost biogas pollutant removal and optimal thermal system integration. Eleven partners from 4 leading biogas countries join efforts to these objectives: 2 biogas cleaning SMEs, 3 SOFC manufacturing SMEs, a biogas expert SME and 5 leading research and education centres in SOFC characterisation and modelling, and in biogas use as a fuel. Two cleaning approaches and hardware will be developed:  one for small scale units (5-50 kWe), where a huge unutilised biogas potential resides (millions of farms, bio-wastes from municipalities) - here sulphur compounds (H2S and organic S) are removed by an appropriate solid sorbent matrix; one for medium-to-large scale units (≥500 kWe), which is the existing scale of landfill biogas and large bio-waste collection schemes - here sulphur compounds and siloxanes are removed among others by a novel cooling approach.  For both cases the hardware will be built and installed on real biogas-sites treating different wastes. Gas analytics will validate the approaches. A 6 kWe SOFC system from a partner will run on a real agro-biogas site connected to the small scale sorbents cleaning unit. Cost projections for high volume production for both the cleaning and SOFC systems will be conducted. A detailed full system model will be implemented, considering the biogas feedstock, composition fluctuations (and dilution) and pollutant signatures, and optimizing thermal integration with biogas-inherent CO2 (for dry-dominant reforming) and digester heating, with the targets to maximise net electrical efficiency and minimise cost. An Advisory Board consisting of biogas producing SMEs will accompan
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Encoding and Transmission of Information in the Mouse Somatosensory Cortex' (ETIC).

assistant: **Concept**

A major challenge in neuroscience is to understand how neurons code information. Optogenetics techniques provide the opportunity of controlling neuronal activity with high temporal and spatial resolution and thus testing causally the role of a specific encoding strategy. However, to enable us to crack the neural code, these optical approaches need to be complemented by theoretical developments that: 1) identify the response variables of a neural population that carry the most information about sensory stimuli and thus allows to build a hypothesis about the neural code it uses; 2) create stimulation protocols specifically designed to rigorously test the hypothesis; 3) apply appropriate statistical analyses that determine whether different information-carrying components of neural population activity are transmitted through downstream networks. Here I will develop a novel theoretical framework to address these issues and understand how the mammalian cortex encodes sensory information, using the mouse somatosensory cortex as an experimental model. I will develop a set of computational techniques aimed at characterizing the encoding and transmission of information in layer IV and then in one of its main targets: layer II/III. Specifically, I will develop Non-Negative Matrix Factorization methods to characterize how large-scale populations of layer IV encode whisker information. I will develop a Wavelet Transform based method to decompose the electrophysiological responses of layer II/III neurons into independently contributing temporal scales and establish which whisker-informative components of layer IV population activity are transmitted to the response of layer 2/3 neurons. This project constitutes a completely novel and comprehensive approach to crack the neural code th