RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Socioeconomic sciences: Communicating Outcomes Oriented to Policy'.

assistant: **Concept**

SCOOP seeks to maximise the potential for dissemination and knowledge transfer of socioeconomic sciences and humanities (SSH) research funded primarily under the Framework 7, but also including key research findings from Framework 6 funded programmes. The project specifically focuses on improving the uptake of SSH research into policy at local, regional, national and European level, with the aim of exploiting the competencies of SSH researchers for the benefit of Europe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Novel materials to improve magnetic resonance imaging' (NOMA-MRI) under Horizon 2020.

assistant: **Objectives**

MRI is one of the most important human clinical imaging modalities. Over the past decade many technological advances have improved image quality substantially. One of the critical trends has been the move towards higher magnetic fields, which has transformed many clinical applications, but has also introduced significant challenges.  These higher fields correspond to higher operating frequencies, which lead to increased image non-uniformities, impairing clinical interpretation, and higher power deposition in the patient, posing significant safety issues. In addition, as the population as-a-whole becomes more obese, high quality MR images become increasingly difficult to acquire even on clinical 3 Tesla scanners. In order to tackle these challenges, MRI systems have become increasingly complicated and expensive.There are two concepts in this proposal which set out to address the issues outlined above. The first is the optimization of high permittivity materials to improve image quality for a number of different clinical applications on a person-by-person basis. This requires a full understanding of the effects of these materials, the ability to predict and manufacture the optimum material, and acquiring the best possible data. The second “high-risk high-gain”concept is a totally new way of constructing MR resonators, which is based on conducting and reconfigurable plasmas. This concept can significantly simplify MR resonator design, can enable completely new types of MR experiment to be performed, and has intriguing possibilities to improve hybrid imaging systems such as combined positron emission tomography/MRI scanners.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Tumor compartment-specific effects of P70S6K in early triple negative breast cancer: regulation of antitumor immune response and therapeutic implications' (P70-IMMUNEBREAST).

assistant: **Concept**

Breast cancer is the most common cancer among women with significant death rates and economic impact. In daily routine clinics, breast cancer is usually classified on the basis of three immunohistochemical markers (ER, PR and HER2). Triple-negative breast cancer (TNBC) is a subtype defined by the negativity of all these markers, which shows an adverse clinical course. It is characterized by a considerable gene expression heterogeneity that leads to a lack of availability of targeted therapies. Positive clinical trials relying on various forms of immunotherapy have shifted the paradigm of diverse malignancies from cytotoxics to novel immunomodulator drugs. The results in TNBC, however, are not as positive. In a recent taxonomic effort of the hosting group, TNBC has been re-classified on the basis of the activation status of six protein kinases, which in turn constituted novel targets for this disease. One of them, the 70-kDa ribosomal protein S6 kinase (P70S6K), which was associated with an adverse clinical outcome, showed negative correlation with tumor-infiltrating lymphocytes (TILs) abundance. The fact that P70S6K has been associated with immunosuppressive mechanisms and that there is a positive correlation between the number of TILs and the clinical outcomes in TNBC, suggests that the role of P70S6K may be related to pleiotropic and/or opposing properties of tumor progression. By using a combination of multiparametric flow cytometry, bulk/single-cell gene expression analysis and in vivo experiments in mouse models, this proposal aims to unravel the impact of P70S6K modulation over the already known relevant immune-oncology targets/axes as well as the therapeutic consequences of P70S6K blockade in TNBC. These studies will provide a better understanding of the lymphocy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Sustainable conservation of animal genetic resources in marginal rural areas: integrating molecular genetics, socio-economics and geostatistical approaches' (ECONOGENE) targeting Fifth Framework.

assistant: **Abstract**

This proposal uniquely combines a molecular analysis of biodiversity, socio-economics and geostatistics to address the conservation of sheep and goat genetic resources and rural development in marginal agro systems in Europe. To assist in site conservation and address the relevant socio-economic factors, we will develop a co-ordinated approach to define strategies of genetic management and rural development. We will greatly extend knowledge of sheep and goat genetic diversity at the molecular level, examine many unstudied, local breeds, and identify gene pools to map conservation priorities. We will produce a map of development perspectives to identify areas where sustainable conservation aft valuable populations could succeed. We will overlay the maps of conservation and development priority and estimate the value of this biodiversity to justify economic intervention, and suggest appropriate guidelines and actions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'MARitime POlicy Support' under Seventh Framework.

assistant: **Concept**

MARPOS aims at assisting the Commission in the implementation of the EU Maritime Transport Policy priorities by utilising the results of past and current research work in Maritime Transport and related expertise from the Transport sector. It addresses the issue by consolidating and synthesising the results of Maritime Transport research in the past two FPs (FP5 and FP6) as well as the current FP7, in order to come up with a set of conclusions about the results of maritime transport research on 5 maritime transport thematic areas, namely, competitiveness, environment ,energy,  safety –security and human factors. Key output of MARPOS will be a publication with the results of the EC funded research work and an easy-to-use searchable database (e-tool) through which all interested parties will have the opportunity to be informed on the results of the European research over the past decade. The e-tool will be updateable providing links to the past and current/future research work in European maritime transport area.The project looks also in detail in the reverse direction, in a way compatible with the requirements of the current Transport programme, the future needs and priorities for EU funded Maritime Transport research so as to better serve the realisation of the objectives of the general Maritime Transport Policy. Finally, an important part of the work is devoted to dissemination and networking actions. These activities include the organisation of 2 major events as well as the use of internet. The aim is to present to various experts, administrators, and policy makers across EU the Maritime Transport research evolution, including objectives and outcomes, and recommendations regarding future Transport research themes & priorities.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Phase-separated block copolymer nanoparticles for spatial organization of enzymes: A new strategy to control enzyme cascade reactions'.

assistant: **Objectives**

Nature has the unique ability to program macroscopic functions via the morphology of nano-scopic systems. One way the cell can control a certain metabolic pathway is by spatial separation of functional macromolecules. Transferring this high level of control to artificial materials would allow not only to study the influence of spatial effects on biochemical pathways, but also to develop new technologies for non-cellular applications. These include the environment-friendly and high-yielding preparation of valuable chemicals or synthetic intermediates. To address this task, the proposed project will exploit the power of controlled block copolymers phase-separation in the confinement of nanoparticles. Nanoparticles can provide structural support and spatial proximity that could ultimately increase product formation. In this context, nanostructured particles are ideal candidates providing unique domains for enzyme compartmentalization by external post-assembly functionalization. In this research project we propose to use poly(styrene)-block-poly(butadiene) nanoparticles as a matrix for post-assembly and domain-selective anchoring of enzymes. For this, two new functionalized polymeric surfactants will be obtained: poly(styrene)-block-poly(ethylene glycol)-""X"" and poly(butadiene)-block-poly(ethylene glycol)-""Y"". Where ""X"" and ""Y"" represent orthogonal reactive groups, which should allow selective attachment of any two enzymes. We proposed the synthesis of striped ellipsoidal nanoparticles where each domain will contain one type of enzyme of a cascade system. We aim for this tandem configuration of one enzyme next to the other to increase the rate of the overall enzymatic reaction. The success of this project could ultimately change the paradigm of the conventional chem
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Best Practice Pilot for the implantation of Integrated Internet Based Remote WOrking Places for Virtual Teams developing their work at SMEs' (IWOP).

assistant: **Innovation**

The IWOP project is a Best Practice Pilot. Its main aim is to foster the integration of technologies enabling the use of mobile and teleworking working, especially in European Small and Medium sized Enterprises belonging to industrial sectors. The project will make 8 trial implementations in firms with very different profiles, to be used as examples to be followed by the rest of European SMEs. Such experience is expected to be repeatable after the project by a significant number of firms (it is expected to reach at least up to 2000 Western and Eastern European SMEs, to relay the experiences reached). With such strategy it is intended to provoke a snowball effect, which will provoke that European SMEs will repeat the experience already achieved in the implantation in the 8 Cases considered in the IWOP project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The Influence of Interfaces, Confinement and Compartmentalization on Chemical Reactions' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Water is essential for life on our planet and is the solvent of choice for Nature to carry out her syntheses. In contrast, our methods of making complex organic molecules have taken us far away from the watery milieu of biosynthesis. Indeed, it is fair to say that most organic reactions commonly used both in academic laboratories and in industry fail in the presence of water or oxygen. At the same time of course, chemical reactors are very different from the cellular environment where Nature s synthesis is carried out. This research proposal aims to incorporate some of the key characteristic of cellular reactors, i.e. confinement, compartmentalization and interfaces, into model droplet-based reactors. The envisioned reactors will comprise of monodisperse aqueous droplets in oil carrier phases with volumes ranging from pL to nL, produced in microfluidics devices or in tubing, in very large numbers. These droplets will have precisely determined interfacial areas, which can be used for the study of so-called on water reactions, a new area of synthetic chemistry rapidly gaining in interest. Furthermore, the interfaces can be functionalized with catalytically active surfactants and by confining the droplets into ever decreasing volumes, the effect of nanoconfinement on enzymatic and other reactions can be studied. Finally, individual droplets provide a completely compartmentalized environment, suitable for the study of single enzymes in a crowded environment, but also for systematic studies into communication between compartmentalized, mutually incompatible, reaction systems. This proposal presents a radically new approach to increasing our understanding of chemical reactions in confined spaces and at interfaces and provides a technological platform for the creation of chemi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Slovak Centre of Excellence in Ion Beam and Plasma Technologies for Materials Engineering and Nanotechnology' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The Center of Excellence SlovakION aims to become Eastern Europe’s leading research centre for ion beam and plasma technologies in materials engineering and nanotechnology. Based on cutting-edge research and closely integrated in an international network of research facilities, SlovakION’s holistic approach to innovation transfer and its close interaction with the regional industry will contribute to the economic development of Slovakia. The main focus lies with the automotive and electronics industry as pointed out in Slovakia’s Research and Innovation Strategy for Smart Specialisation.The TEAMING project shall help to develop the new Centre of Excellence as an internationally acclaimed source of excellent research. In close cooperation with the Slovak government and relevant industrial partners, SlovakION will establish and develop an integrated system for technology transfer and applied research. As a long term vision, this Slovak transfer model should be extended on other areas of research and industrial fields.The SlovakION project draws its strength from three major sources: (i) STU is Slovakia’s leading technical university with a long tradition of excellent research and education, (ii) As of today, already €42M has been committed for creating a state-of-the-art facility for ion and plasma technologies. These funds were provided by the European Structural Investment Fund (ESIF), the Slovak Republic Government and the STU, and (iii) HZDR Dresden will be the leading support for SlovakION building on more than a decade of close collaboration. HZDR will not only bring its own experiences in breeding excellent research and develop fruitful technology transfer, but could draw on the whole Dresden research cluster including a leading technical university, several themat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Creating a Central European Thermal Water Research Cluster' (CLUSTHERM), addressing dissemination and exploitation.

assistant: **Impact**

Central Eastern Europe’s rural areas have been facing great challenges due to their geographical handicaps and economic structural problems, although they possess an unexploited natural treasure: the thermal water.   The overall concept of the CLUSTHERM project is: enabling the regional actors to bring the geothermal R&D achievements to the ground of local services and products.   Access to research provision and the clustering between the economic and public actors could allow the dynamic, knowledge based development of these rural economies. A more concentrated research on geothermal resources can lead to the development of high added value products and services.  The CLUSTHERM project aims to set up a new research driven cluster in Central Europe on thermal water utilization that will develop the capacity and research potential of Central Eastern Europe’s rural economies rich in thermal water to access and benefit from research on the exploitation.  The direct objectives are: - analyse the RTD development and the needs of geothermal energy utilisation - promote synergies and catalyse links between regional, research and business actors (vertical clustering) - foster the transnational and cross-border co-operations between the regional actors (horizontal clustering) - develop and enhance transnational mutual learning through information exchange possibilities of regional stakeholders in creating research driven clusters and to disseminate good policy practices and benchmarking activities - develop joint action plan and research strategy among the participating regions to increase the regional economic competitiveness through concentrated use of natural resources
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Advancing integrated risk assessments of cropping systems in sub-Saharan Africa' (IRACS) targeting Horizon Europe.

assistant: **Abstract**

In sub-Saharan Africa (SSA), attaining food security is crucial for the United Nations Sustainable Development Goal of 'Zero Hunger'. Despite this, malnutrition rates of SSA in 2022 have deteriorated compared to 2010. Climate change further compounds this challenge, as it affects the SSA cropping system—the bedrock for the local food system but highly vulnerable to environmental shifts. The condition seems more severe here in the future: not only a higher frequency of extreme weather events occurring but also more outbreaks of pests and diseases. Surprisingly, most agricultural risk analyses on SSA have overlooked the impact of pests because few regional crop models can address its simulation. Moreover, most studies about SSA focused on quantifying yield loss risk but the overarching goal of agriculture risk assessment should be to elucidate the associated economic ramifications as a basis for policy responses. This project, IRACS, seeks to answer: ""What is the integrated risk of crop failures in SSA under climate change, and what are its subsequent economic implications?"" To tackle this, the IRACS will first develop a new pest model. This will be integrated with an enhanced crop model to better predict crop failure risks. Subsequently, applying future scenario datasets, this coupled model will assess potential yield loss in SSA. An integrated assessment model, GLOBIOM, will then be employed to assess the associated economic impacts. Ultimately, the IRACS initiative aims to not only deepen understanding of the interplay between climate change, cropping systems, and farmer livelihoods in SSA but also show how to combine biophysical models with economic models to investigate climate change impact effectively.""


**Keywords:** agricultural risk, crop pests, crop model,