RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Smart Building Ecosystem for Energy Communities' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

By 2050, 98 million Europeans could become prosumers by joining an energy community. The REScoopVPP project combines front-runner energy communities to create the most advanced community-driven smart building ecosystem for energy communities. The ecosystem consists of a Community-driven Flexibility Box (COFY-Box) acting as smart home controller, and a set of community tools to support energy services for aggregators, ESCO’s, BRP’s and suppliers of RES.The COFY-box will be the first truly open and collaborative building controller, based on existing open source home automation technology with more than 1.400 integrations. The COFY-box will be affordable and easy to install. Community tools will enable energy communities to become real-time asset operators by employing demand and production forecasting algorithms, a dynamic pricing module for implicit DR and an OpenADR-based explicit DR solution.REScoopVPP solutions will undergo a large-scale experimentation in Belgium, France, Germany, Spain and the UK. The project will improve EV, PV and electric battery control, and will especially focus on the intelligent integration of thermal storage and hybrid heating solutions, capable of shifting fossil fuel consumption from legacy DHW and heating equipment to flexible renewable heat. Further attention will be given to smart plug control and the integration of equipment based on emerging EU-standards. This will improve comfort, while not adversely affecting original functionalities, quality and lifetime of the equipment.The ecosystem of REScoopVPP has the potential to impact 375.000 customers 5 years after the project and thus trigger primary energy savings of 559 GWh/year and improve the SRI of houses by 2 steps on average. To make sure that the ecosystem is viable, REScoopVPP w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'European methodology for regional innovation policy impact assessment and benchmarking' (EMERIPA), addressing dissemination and exploitation.

assistant: **Impact**

The overall objective of EMERIPA is to develop and test a transferable European methodology and associated tools which will enable the regional actors to assess the effectiveness of their regional research and innovation policies within a European framewor k and to benchmark and recommend policies for increasing their regional performance in terms of Sustainable Development. Since the mid-90s, the EC has supported EU regions to formulate or deepen innovation policies to improve their innovative capacity and optimise their regional innovation policy and infrastructure. Nowadays, many of the traditional regional policy strategies no longer apply. Innovation policies need to be flexible and undergo a constant process of assessment. The purpose of EMERIPA stems f rom these challenges by means of: developing a European methodology, new common tools and indicators which help to assess innovation policy impact; the evaluation of the impact that the regional research and innovation policy framework is having on the reg ional innovation system/economy of the participating regions; a benchmarking exercise and good practices exchange; a Dissemination and Awareness rising campaign during the whole duration of the project. An analysis of the different regional performances an d a consensus on conclusions about the regional situation will be achieved. As a final stage, innovation policy recommendations will be outlined and the methodology, associated tools and indicators will be integrated into the mainstream regional research a nd innovation policies in the regions. EMERIPA consortium represents all geographic areas and different regional innovation strategies (EU and non-EU funded) for assuring an optimal and wide vision of all the features. EMERIPA has 8 partners representing t he
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Of DNA methylation and looping of distant regulatory elements in mantle cell lymphoma' in the context of a Seventh Framework call.

assistant: **Objectives**

B-cell differentiation is a complex process in which epigenetic changes, i.e., DNA methylation and histone modifications, play an essential role to regulate gene expression. Disturbances in epigenetic processes can result in development of B-cell malignancies, such as mantle cell lymphoma (MCL). So far, little is known about the epigenetic alterations underlying MCL. In general, epigenetic studies in cancer have mainly dealt with identification of hypermethylated promoter regions. Recent genome-wide studies in B cell malignancies however, have shown that the majority of DNA methylation changes do not occur in promoter regions but at intra- and intergenic loci, which are enriched for enhancers. In this project, I wish to study the functional impact of DNA methylation changes at these enhancer regions on DNA looping and gene expression regulation in MCL. To achieve this goal, I will generate genome-wide chromosome conformation maps of MCL and normal naive B cells using Hi-C sequencing. Additionally, I will generate DNA methylation profiles, histone modification maps and gene expression profiles of these samples. Combining these datasets will allow identification of intra- and intergenic enhancer regions that, based on differences in DNA methylation status, affect DNA looping and gene expression. The effect of DNA methylation on enhancer activity of these regions will then be studied in further detail using luciferase reporter assays. The proposed study shall give insights into (i) the effect of DNA methylation outside promoter regions on DNA looping and gene expression (fundamental aspect); (ii) the DNA methylation changes in MCL that affect these processes (biological aspect); and (iii) the functional impact of differential DNA methylation between MCL subtypes (clinical
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Accelerator and Magnet Infrastructure for Cooperation and Innovation' under Horizon 2020.

assistant: **Concept**

Development and construction of accelerator based scientific Research Infrastructures are going through a deep paradigm change because of the need for large scale Technological Infrastructures at the forefront of technology to master the key accelerator and magnet science and technology needed for several fields. Indeed, because of the high technological level and of the increased size and time scale of projects, development and construction require more and more sophisticated R&D platforms on key accelerator and magnet technologies, large-scale facilities for their assembly, integration and verification, large concentrations of dedicated skilled personnel and long term relationships between laboratories and industry. In response to those challenges, a few large platforms specialized in interdisciplinary technologies and for applications of direct benefit to society are emerging. The emerging Technological Infrastructure is aiming at creating an efficient integrated ecosystem among laboratories focussed on R&D, with a long term vision for the technological needs of future RIs and industry, including SME, motivated by the innovative environment and the market created by the realisation of the technological needs of several RIs. With a timeline of 30 months, involving 10 Consortium partners, the AMICI proposal will ensure that A) a stronger and optimised integration model between the large existing technological infrastructures is developed and agreed upon, B) that this integrated ecosystem is attracting industries and fostering innovation based on accelerator and SC magnets cutting-edge developments, C) that strategy and roadmaps are clearly defined and understood to strongly position European industries and SMEs on the market of the construction of new Research Infrastr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Human leukemic stem cells: from identification towards targeting and eradication', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Human myeloid leukemias are life-threatening disorders. Although with current therapies the bulk of the tumor is readily eradicated, it is particularly the rare population of leukemic stem cells (LSCs) that is relatively quiescent and is very difficult to target. As a consequence, relapse of the disease occurs frequently resulting in poor survival rates. Nevertheless, remarkable differences do exist between subsets of patients. It is important to realize that leukemias are rather heterogeneous disorders that can be caused by a multiplicity of genetic and epigenetic changes. One of the most important challenges in the field today lies in establishing which of the differences between LSCs and normal hematopoietic stem cells (HSCs) provide attractive targets for the identification, targeting and ultimately the selective eradication of LSCs. Given the heterogeneity of the disorder, it will be important to address these aspects in detail in a leukemia subtype-specific manner.Central to this proposal is the establishment of a human xenograft mouse leukemia “clinic” in which all important human leukemia subtypes will be represented. LSCs from patients as well as from cord blood and bone marrow model systems that we have generated will be equipped with luciferase-GFP tracers in order to allow detection of leukemic development in alive immunodeficient mice, as well as with unique barcodes that will allow clonal tracking. Within this mouse clinic, in a leukemia subtype-specific manner, we will be able to: 1) identify (novel) leukemic stem cell markers and evaluate their targetability; 2) evaluate whether stem cell intrinsic versus extrinsic signaling can be used as targets in alternative approaches to eradicate LSCs, and 3) study clonal evolution from de novo to relapsed leukemia
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'FULLY INTEGRATED ANALYSIS, DESIGN, MANUFACTURING AND HEALTH-MONITORING OF COMPOSITE STRUCTURES' in the context of a Horizon 2020 call.

assistant: **Objectives**

Composite structures are massively exploited in many engineering fields. For instance, the state-of-the-art civil aircraft (B787 and A350) are mostly made of composite materials. The design of composites leads to challenging tasks since those competencies that stemmed from the adoption of metallic materials are often inadequate for composites. Insights on many different disciplines and tight academic/industrial cooperation are required to fully exploit composite structure capabilities. The skills and the employability of young researchers increase to a great extent through an interdisciplinary and intersectoral training. The existing training schemes are often based on specific themes and disciplines rather than on a broad interdisciplinary and academic-industrial integrated approach. The main aim and novelty of this project is the creation of a multidisciplinary, intersectoral and international research training network based on a strong academic basis and industrial partnerships for a new generation of top talented young researchers that will work in the European academic and industrial scenarios. The multidisciplinary features are guaranteed by the presence of 7 universities, 1 research centre and 1 industry. The intersectoral approach will be pursued by including secondments and specific industrial training requirements in each individual project. The consortium is composed by partners from 8 countries. OTC partners were included for secondment and training opportunities; they were chosen on the basis of their expertise and to enhance the internationality features of the training. Their presence is seen as an opportunity for the European partners and researchers to strengthen competencies. The full spectrum of the design of composite structures will be dealt with -
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Entropy-driven model reduction for fluid flows', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Turbulent fluid flows play a critical role in science and engineering in energy, process design, climate and life sciences. Accurate and efficient computational fluid dynamics (CFD) simulation tools are therefore essential. As resolving all turbulent scales of motion is computationally infeasible, every CFD code requires a closure model to represent the effect of unresolved scales. A recent paradigm shift is to construct closure models by combining physics- and data-driven methods. However, these lack the cornerstones of mathematical-physical modelling of fluid flows: stability, physical consistency and accuracy guarantees.In SYMBIOSIS I develop a radically novel approach to construct closure models. I propose entropy as concept to bridge physics- and data-driven models: the mathematical-physical concept of entropy is used to enforce stability and physical consistency, while the information-theoretic concept of entropy provides a new view on measuring accuracy. Together they provide an innovative framework for accurate probabilistic predictions of turbulence that I apply to simulate wind-turbine wakes and CO2 transport.Both entropy concepts are combined in three steps to construct new closure models. 1) I propose a new entropy-stable model reduction strategy, providing the environment for effective development of closure models. 2) I propose a new entropy-stable stochastic formulation of the fluid flow equations, providing a powerful way to model uncertainties arising from initial conditions, fluid properties, and neglected small scales. 3) I propose a new entropy-stable data-assimilation strategy to enable continuous updating of the closure model and flow field with observation data. The result is a new foundational mathematical framework for simulating turbulent flows
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'PUBLIC HOUSING RETROFITS WITH THE INTEGRATION OF SOLAR TECHNIQUES IN THE MUNICIPALITY OF TAVROS - GREECE' (1994-1998).

assistant: **Innovation**

The aim of the project is to reduce the current heating and cooling requirements of two different housing buildings (10 floor and 4 floor), by 86% and 35-40% respectively. In order to achieve these targets, innovative technologies will be incorporated, such as : - External insulation of all facades- Integration of passive solar systems- Installation of water solar system- Photovoltaic panels.The project concerns the design, construction and extensive monitoring of two typical public housing units in the area of Tavros. - Type A represents the older type of units built around 1950. These are bar-shaped 4-store buildings, with simplified and standardised construction. They have no insulation or central heating and have been extensively modified by tenants, who are also in most cases the owners of each apartment. In the area of Tavros there are 6 buildings of this type.- Type B is a more recent type of building built around 1960. It is a 10-store building with a more elaborated construction and central heating. These units have a basic disadvantage in the orientation of the apartments, which face mostly east-west orientation and have little south exposure. In the area of Tavros there are 10 buildings of this type.1. The design of the retrofitting measures for the two buildings will include the following :- passive solar design features- external insulation of walls and roofs- natural ventilation strategy design- design of glazing for daylighting- internal air quality studies- civil engineering metal constructions- solar air heaters design- solar water design- photovoltaics- electrical and mechanical systems design- plumbing and electrical installations2. In addition to the design, simulations will be carried out concerning :- the thermal performance of the building before
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Eco-lightweight granules for energy efficient applications' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Buildings in Europe are responsible for more than 40% of total energy consumption and 25% of carbon emissions, mainly due to the high number of old housing stock with very poor insulation systems. This research will develop new energy efficient materials by engineering eco-lightweight granules (eco-LWG) to mitigate these problems. The eco-LWG will have high strength and high water absorption, ~100 wt.%, and be made from widely available waste materials: recycled mixed coloured glass, clay and limestone. The eco-LWG will be used to contain phase change materials (PCM), which use chemical bonds to store and release heat, allowing control of temperature fluctuations. The high level of porosity in the eco-LWG will allow them to absorb and retain much higher levels of PCM than has previously been possible using existing lightweight aggregates. Both the eco-LWG and the PCM loaded eco-LWG will be optimised by statistical design methodology and they will be used to develop new energy efficient construction products. Two impregnation methods will be compared to introduce the PCM into the eco-LWG: vacuum sorption to achieve maximum PCM uptake and short term immersion to partially fill the connected porosity. These will produce innovative lightweight and high heat-storage materials. Incorporating PCM loaded granules in mortars and other construction materials will result in reduced energy requirements to heat and cool buildings and improve indoor living conditions. The eco-LWG developed in this research will also be used in green roofs to provide water retention capacity and slow nutrient release. Green roofs can reduce the energy requirements of buildings and urban pollution. This multidisciplinary innovative research will deliver new energy efficient construction materials that
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Wastewater Treatment Monitoring and Advisory System' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The biggest pain point of WaMoS customers, i.e. small and medium size Urban Waste Water Treatment Plants (UWWTP, 18.842 in EU), is that state-of-the-art of commercially available technological solutions for real-time and online monitoring of aerobic biological nutrient removal (BNR), responsible for cleaning of organic pollutants from wastewater, does not meet the demands of the market. Lack of suitable solutions forces operators of UWWTPs to »drive blind« in critical situations. This often results in discharge of pollutants into receiving rivers with estimated environmental cost of  300 million EUR per year in EU.Our innovation : WaMoS is affordable online, real-time, monitoring, diagnostic, alarming and advisory system for monitoring BNR process status, designed as Platform as a Sevice (PaaS). Our Key enabling technology is industrial biotechnology supported by Artificial Intelligence/Machine Learning (AI/ML), Internet of Things (IoT) and blockchain technologies. It can completely remove risks of  pollution due to problems with BNR process and as such it is an industry gamechanger. Our target is 80% reduction of unwanted biological treatment events during operation of small and medium size UWWTPs. Our customers are reponsible for cleaning waste water of 150 million inhabitants of European Union.WaMoS is positioned as Smart Water Technology , available market amounts to 360 - 400 million EUR globally, we target market share of 30% till 2025. The main market drivers are new EU legislation, technology (IoT, ML/AI, blockchain) and strong public pressure. Our main competitor is Hach RTC solution, which is still too expensive. WaMoS will be launched on the market for the 3rd of the price of the competition.Our unique competitive advantage is a combination of long-term (30 y