RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Shaping the bacterial cell wall: the actin-like cytoskeleton, from single molecules to morphogenesis and antimicrobials' (BACTIN).

assistant: **Innovation**

One of the ultimate goals in cell biology is to understand how cells determine their shape. In bacteria, the cell wall and the actin-like (MreB) cytoskeleton are major determinants of cell shape. As a hallmark of microbial life, the external cell wall is the most conspicuous macromolecule expanding in concert with cell growth and one of the most prominent targets for antibiotics. Despite decades of study, the mechanism of cell wall morphogenesis remains poorly understood. In rod-shaped bacteria, actin-like MreB proteins assemble into disconnected membrane-associated structures (patches) that move processively around the cell periphery and are thought to control shape by spatiotemporally organizing macromolecular machineries that effect sidewall elongation. However, the ultrastructure of MreB assemblies and the mechanistic details underlying their morphogenetic function remain to be elucidated. The aim of this project is to combine ground-breaking light microscopy and spectroscopy techniques with cutting-edge genetic, biochemical and systems biology approaches available in the model rod-shaped bacterium Bacillus subtilis to elucidate how MreB and cell wall biosynthetic enzymes collectively act to build a cell. Within this context, new features of MreB assemblies will be determined in vivo and in vitro, and a “toolbox” of approaches to determine the modes of action of antibiotics targeting cell wall processes will be developed. Parameters measured by the different approaches will be used to refine a mathematical model aiming to quantitatively describe the features of bacterial cell wall growth. The long-term goals of BActin are to understand general principles of bacterial cell morphogenesis and to provide mechanistic templates and new reporters for the screening of novel
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Robust Control, State Estimation and Disturbance Compensation for Highly Dynamic Environmental Mechatronic Systems' (CLOVER) targeting Horizon 2020.

assistant: **Abstract**

The main goal of the CLOVER project is to offer a novel methodology in an environmental mechatronic control system design relying on multidisciplinary knowledge. This methodology should allow aspects to be taken into account, such as controller robustness, indirect measurement of system states and parameters, and disturbances attenuation on the stage of establishing controller architecture. In addition, methods for tuning the control algorithms will be developed and based on the solution of optimization task considering control priorities, such as environment friendliness and energy efficiency. The implementation of the project CLOVER is based on intensive staff exchange that will lead to collaborative research and training between universities and industrial organizations from Germany, Austria, Belgium, Norway, UK, Mexico, and Japan. To guarantee a strong focus of the project activities on real-world problems, the CLOVER concept is based on the R&D and training in three interfacing topics: “Mechatronic chassis systems of electric vehicles”, “Mechatronic-based grid-interconnection circuitry”, and “Offshore mechatronics”, which will identify and facilitate collaborative learning and production of innovative knowledge. The CLOVER objectives will be achieved through intensive networking measures covering knowledge transfer and experience sharing between participants from academic and non-academic sectors, and professional advancement of the consortium members through intersectoral and international collaboration and secondments. In this regard, the CLOVER project is fully consistent with the targets of H2020-MSCA-RISE programme and will provide excellent opportunities for personal career development of participating staff and will lead to the creation of a strong European
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'optimization of Particle Accelerators: A Marie Curie Initial Training Network' to be submitted under Seventh Framework.

assistant: **Abstract**

There are more than fifteen thousand particle accelerators in the world, ranging from the linear accelerators used for cancer therapy in modern hospitals to the giant 'atom-smashers' at international particle physics laboratories used to unlock the secrets of creation. For many decades these scientific instruments have formed one of the main pillars of modern research across scientific disciplines and countries.The optimization of the performance of any particle accelerator critically depends on an in-depth understanding of the beam dynamics in the machine, the availability of simulation tools to study and continuously improve all accelerator components from beam handling elements to rf cavities, a complete set of beam diagnostics methods to monitor all important machine and beam parameters with high precision, and a control and data acquisition system that links all the above.The oPAC consortium proposes to carry out collaborative research into all the above aspects, with the aim to optimize the performance of present and future accelerators that lie at the heart of many research infrastructures. The network brings together leading research centers, universities, and industry partners to jointly train the next generation of researchers in this interdisciplinary field. oPAC aims at developing long term collaboration and links between the involved teams across sectors and disciplinary boundaries and to thus help defining improved research and training standards in this important field.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'An integrated emergency response decision support system for enhancing workers’ safety in offshore oil & gas operations' (OffshoreMuster), addressing dissemination and exploitation.

assistant: **Impact**

OffshoreMuster introduces as step-change in mustering and evacuation management in offshore platforms thanks to its unique features: continuous localisation and health monitoring of crew-members, detection of people at sea at distances of up to 1.5km and robust communication even in the events of massive data link breakdowns. Off-shore infrastructure has been growing steadily over the past years. To meet increasing demand, most future growth will have to come from fields that are more technically challenging and expensive to extract from than previously, such as deep- and ultra-deep-water offshore sites, This growing demand will drive investment in offshore oil & gas projects, and the increased activity in turn will drive an increase in demand for offshore assets to support these activities.This expansion comes at a great cost; upstream oil & gas has one of the highest severe-injury rates in the world, with a 2015–2016 rate of 148.9 injuries per 100,000 workers. This rate is unsurprising, considering the industry’s culture in which worker safeguards may not get the attention they deserve. Fatality rates are equally staggering: offshore workers face an average of 27.1 deaths per 100,000 employees. In every case with casualties, there were extensive shortcomings to the evacuation procedures. These are exacerbated by a lack of communication between the command structures and the platform’s crew, or the crew themselves.OffshoreMuster is based on the successful outcomes of previous R&D projects, during which the consortium partners successfully developed a system for safe mustering and evacuation in marine environments. Having demonstrated the technology, we aim to enhance the safety of personnel working in off-shore oil & gas installations and assets. By bringing the techno
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Discovering a novel allergen immunotherapy in house dust mite allergy tolerance research', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The advances in medical sciences and biopharmaceutical development during the last decennia have been overwhelming. While the scientific and clinical insight in numerous diseases have significantly increased, the curative treatment to most diseases is still not in reach. The most common diseases such as cancer and chronic diseases are still challenging scientists. Therefore, during our ERC Advanced project the main goal was to develop a vaccine to cure cancer using targeted immunotherapy. We used dendritic cells (DCs) as potentiator to improve anti-tumor T cell activity. However, we discovered that many tumors display a high content of sialic acids which actively suppress DCs function and induce tolerance to tumor associated antigens. This unexpected serendipity finding that sialylation of tumor associated antigens induced tolerance to the body’s immune response opens a window of opportunity to use sialylation (modification with sialic acid) to induce tolerance in allergies, such as house dust mite allergy (HDM). In the ERC PoC project (MATCH) I will couple HDM major allergens to specific sialic acid using a linker molecule to induce immune tolerance towards effector T cells in inflammation processes during HDM allergy. The results will lead to validation of the technology developed during the ERC Advanced project and PoC that sialylation induces tolerance when used with HDM allergens. When PoC is reached, the MATCH technology will represent a new allergen immunotherapy in a vaccine technology for HDM allergy with shorter treatment protocols, better efficacy and reduced side effects can be developed. The future potential of this technology may be extended to other allergies and/or autoimmune diseases.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Reappraising Western European Repertoires for Puppet and Marionette Theatres' (PuppetPlays) under Horizon 2020.

assistant: **Objectives**

This project aims at transcending boundaries between « high » and « popular » cultures, here established playwrights and anonymous writers, by investigating their productions for a same medium: puppet and marionette theatre. Focusing on key-periods of drama history (1600-2000) it explores how puppeteers and authors both contribute to the raise of a specific dramaturgy. Introducing these repertoires into the history of Western European drama opens a double ground-breaking perspective: on one side, it exceeds the limits of local inquiries and reveals cultural transfers through social groups and nations; on the other, it leads to reexamine theatre historiography by considering the cohesion of “theatrical systems” (Marotti) and giving visibility to a long despised and scatered corpus. The main objectives are 1) to gather a corpus of representative plays which document the development of puppetry in Western Europe (Austria, Belgium, England, France, Germany, Italy, Nederlands, Portugal, Spain); 2) to identify the specific features of puppet and marionette plays and their variations through time, cultural areas, conditions of production and targeted audiences; 3) to re-evaluate the contribution of these repertoires to the construction of European cultural identity. The principal investigator brings to this project, besides a long experience of internationally recognized research, an excellent knowledge of artistic and cultural networks which guarantees the access to primary sources as well as the mobilisation of experts and partner institutions. Using digital humanities tools and methods, the project will produce a platform making available the selected corpus through a data base and searchable thesaurus, and offering innovative resources to the research community, pedagogues
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Audio-based Mobile Health Diagnostics' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Mobile health is becoming the holy grail for affordable medical diagnostics. It has the potential of associating human behaviour with medical symptoms automatically and at early disease stage; it also offers cheap deployment, reaching populations generally not able to afford diagnosis and delivering a level of monitoring so fine which will likely improve diagnostic theory itself. The advancements of technology offer new ranges of sensing and computation capability with the potential of further improving the reach of mobile health.  Audio sensing through microphones of mobile devices has recently being recognized as a powerful and yet underutilized source of medical information: sounds from the human body (e.g., sighs, breathing sounds and voice) are indicators of disease or disease onsets.  The current pilots, while generally medically grounded, are potentially ad-hoc from the perspective of key areas of computer science; specifically, in their approaches to computational models and how the system resource demands are optimized to fit within the limits of the mobile devices, as well as in terms of robustness needed for tracking people in their daily lives. Audio sensing also comes with challenges which threaten its use in clinical context: its power hungry nature and the fact that audio data is very sensitive and the collection of this sort of data for analytics violates obvious ethical rules.   This work proposes models to link sounds to disease diagnosis and to deal with the inherent issues raised by in-the-wild sensing: noise and privacy concerns. We exploit these audio models in wearable systems maximizing the use of local hardware resources with power optimization and accuracy in both near real time and sparse audio sampling. Privacy will arise as a by-product taki
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'EU Fruit Network' (EUFRUIT).

assistant: **Concept**

The European Fruit Network (EUFRUIT) includes 12 countries focussed on 4 thematic areas of critical for the competiveness and innovation potential of the European Fruit sector: i) new cultivar development and evaluation; ii) minimise residues on fruit and the environment; iii) optimising storage and fruit quality; iv) sustainable production systems. EUFRUIT will coordinate and support innovation through developing a framework for relevant stakeholders and it will establish a systematic approach for knowledge gathering and dissemination. The systematic approach includes: i) scanning & synthesis via 4 expert groups who scan state-of-art knowledge, practises and technologies and synthesise the material to identify key areas of learning and best practise approaches at a European level. ii) showing & sharing will deliver outreach/dialogue at a national level through establishment of local ‘operational groups’. An online Knowledge Platform will hold all outreach material, outreach activities include; 100 industry publications, 90 technical bulletins, 25 flyers/newsletters, 60 seminars, 160 field based meetings, 25 conference plus 12 events aimed at the general public. iii) sustaining the network will occur through long-term integration of the assembled EUFRUIT network in future actions. The overall outcome of EUFRUIT will be establishment of a framework and a systematic approach that together builds a bridge across the ‘valley of death’. This bridge will secure a direct path for new knowledge in the future and reduce the likelihood of repetition of research at a national level. The European fruit sector will have ready access to up-to-date information to implement and value will be created both for the industry with respect to competitiveness, sustainability and efficiency an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Molecular phylogeny and evolution of specialization in anemonefishes and in their host sea anemones' (2002-2006).

assistant: **Innovation**

The relationship existing between speciation rate and degree of specialization in fishes and more generally in organisms has been described but never fully exploited. The research we proposed focuses on a widely speciating group of marine fishes, the so-ca lled anemonefishes or clownfishes. Anemonefishes all belong to only two genera: Amphiprion (27 species) and Premnas (1 species). The two genera comprise only anemonefishes, These groups of fishes and the tropical sea anemones that host them are an astonish ing example of extreme specialization resulting in the evolution of a symbiotic behavior involving two animal species. Some anemonefishes are specialized to cooperate with a single or few species of sea anemone, being immune to their poisonous tentacles bu t sensible to those of other species of sea anemones, while other anemonefishes are more generalist and able to live together with a number of different kind of anemones. Anemonefishes diffuse through a pelagic larval form that can last about 4 weeks. The main goals of the project are to elucidate the process of speciation that anemonefishes went through and tc construct a comprehensive phylogeny of the taxon, to investigate the evolution of specialization in anemonefishes through character reconstruction a nalyses, to construct a partial phylogeny of those see anemones that act as a host to anemonefishes and to possibly elucidate the co-evolution of anemonefishes anu sea anemones. The originality of the proposal is clearly stated by the almost complete la ck of studies on the proposed subject. The proposed project fits perfectly well with the overall objectives that the European Union is currently setting as priority in the Sixth. Framework Programme. We believe that the structuring of the European Research Area
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Joycenstein: James Joyce, Gertrude Stein, and the modernist coterie.' to be submitted under Horizon Europe.

assistant: **Abstract**

The aim of this Fellowship is for the researcher, Dr Dr Georgina Nugent-Folan, to develop the professional prowess, high-impact dissemination, advanced training and practical experience commensurate with the role of a leading independent researcher in the EU. The researcher will be based for 24 months at the University of Vienna (UV), supervised by Professor Dr Sylvia Mieszkowski. Research training will be implemented through an interdisciplinary project that conducts the first extended comparative study of the modernist writers James Joyce and Gertrude Stein. The project will compare their styles across all their major works, exploring how their contrasting aesthetics has shaped contemporary understandings of modernism. The project will also investigate the fabled antipathy they harboured towards each other, and how this has influenced subsequent critical engagements with their works. The key output will be the first monograph to be written on Joyce and Stein, but the project will also communicate knowledge to a public audience through appropriate outreach activities. The researcher will access expertise, mentoring, advanced training and gain access to the Vienna Centre for Irish Studies (CIS), the most prestigious centre for Irish Studies on the European continent. Due to its unique position as the host of the CIS, together with the interdisciplinary support and mentorship available from the supervisor, the UV is the best institution in Europe for hosting this project. The researcher will be given the opportunity to disseminate and embed her new research through conferences and a symposium. The resources of the host institution will facilitate development of an interdisciplinary and international academic network, together with career-mentoring. The Fellowship will es