RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Molecular genetic dissection of chromosomal fragile sites' under Seventh Framework.

assistant: **Concept**

Chromosomal fragile sites (CFS) are naturally occurring hot-spots for DNA breakage. CFS are frequent breakpoints for chromosome translocations, prone to expansion of repetitive elements and susceptible to other types of genetic instability. Chromosomal fragile sites have therefore been linked to several types of cancer as well as to neurological disorders such as obsessive-compulsive disorder, type I bipolar disorder, schizophrenia and Fragile X syndrome. In most cases, CFS are cytogenetically defined megabase regions of the genome and the underlying molecular mechanisms and genetic requirements for fragile site instability are unknown. This is largely due to the difficulty of genetic manipulation of these elements in human cells. In order to investigate the molecular mechanisms and genetic requirements that control fragile site stability, we will take advantage of two genetic model systems, the yeast Saccharomyces cerevisiae and the vertebrate DT40 cell line (Gallus gallus), which allow for genome-wide screens and genetic manipulation to test specific hypotheses regarding chromosomal fragile sites.The goal of this project is to perform a molecular, genetic and cell biological analysis of CFS. Specifically, the aims of this project are (i) to identify the genetic requirements for fragile site expression (ii) to isolate and characterize proteins that bind to fragile sites and (iii) to investigate the impact of transcription, replication and chromatin structure on fragile site expression.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Develoment of a prosthesis for voice restoration after total laryngectomy' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Surgical treatment of a malignant tumor in the throat often results in removing the larynx (with the vocal folds and epiglottis). This treatment, called laryngectomy, has very radical consequences. The trachea is lead outside through an opening (stoma) in the neck which is alxays visible and thus vurdens the patient psychically. A shurtvalve is placed between the esophagus and trachea. Speech is only possible bny closing the stoma with a finger, hereby forcing the expired air to flow through the shuntvalve into the esophagus. This produces very limited speech of low frequency and a reduced loudness. Althoough this is a life saving treatment there are major disadvantages of which the poor quality belching like speech is one of the most important. We aim to eliminate this drawback by developing a fully imolantable voice restoring prosthesis which enables individual adjustment of frequency and intensity of speech and will produce a sound that copies the sound of natural vocal folds. This prosthesis for the vocal forlds can be incorporated in the shunt valve which is placed between the trachea and esophagus. The project will be ended with a protoype which is tested in vitro and in vivo. Further development of the prosthesis at the end of the project is required in order to create a product suitable to conduct a clinical evaluation and adjustmenst that will allow mass production.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Magnetostrictive bilayers for multi-functional sensor families' (B-SENS).

assistant: **Innovation**

New bilayer (BL) material category as a basic element for multi-functional sensor families with potential to replace many conventional sensor types (e.g. temperature, acceleration) through identical design. BL consisting of a magnetostrictive layer (ML) and a nonmagnetic counter-layer (CL), bending yielding pure compression in the ML as a basis for a sensor signal (sensitivity adjustable by the CL- design). Development of production procedures (sputtering, agglutination, melt spinning) for macro-BL strips (thickness order 100 µm) by P1/HES, micro-BLs (1 µm) by P2 / HES and BL-wires (>1 µm) by P3/REC mainly using amorphous MLs. Material characterization by P4/REC. Signal establishment methods including non-contact detection. Applicability tests for automotive sensors (e.g. vehicle driver condition, torque) by P5/IND and clinical monitoring (skin sensors for cardio-respira- tory functions, catheder sensors for blood velocity, temperature, etc.) by P6/IND.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'An ENErgy Retrofit FUNDing rating tool' (ENERFUND).

assistant: **Concept**

ENERFUND is a tool that will rate and score deep renovation opportunities – like a credit score used by banks to rate clients. The tool will be based on a methodology to be developed and on a set of parameters such as EPC data, number of certified installers, governmental schemes running, etc. By providing a rating for deep renovation opportunities – whether for private establishments or for public buildings – funding institutes can provide targeted loans, retrofit companies can identify sound opportunities, municipalities can promote targeted incentives and the public's trust for retrofitting will be enhanced.The objectives of the current proposal is to (a) analyse the status quo and needs of deep renovation stakeholders and the public, (b) build upon the outcomes of previous projects to create a tool for deep renovation financing, (c) promote the tool to all interested stakeholders, (d) measure and document the impact of the tool on deep renovation strategies and financing and (e) provide a powerful tool that will assist EU stakeholders meet their obligations on increasing renovation rates.The partners, from 12 countries, include 2 universities, in charge of the project management and the development of the methodology behind the tool, 2 SMEs with extensive experience on database management, EPC mapping, development of online decision-making tools, and 11 Ministries, Energy Agencies, NGOs, etc that are connected with the relevant stakeholders throughout Europe and can promote the tool.The expected impact is approximately 45GWh due to the use of the tool to promote deep renovation of buildings and through our training and dissemination activities. ENERFUND will account for approximately 1% of the current annual renovation rate during the project duration. The strategic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Mapping the Virological Consequences of 5500 years of Domestication and Shifting Breeding Practices in Horses and Donkeys'.

assistant: **Innovation**

The emergence of animal domestication and farming practices during the last 10,000 years is thought to have enhanced humans' exposure to infectious diseases, but the consequences of these developments for the health of domesticated animals themselves have been largely overlooked. Understanding the long-term effects of domestication and breeding practices on the epidemiology and evolution of animal pathogens is yet of foremost importance given current concerns regarding modern farming practices and their impact on animal and public health. Recent major advances in sequencing and biomolecular techniques have allowed the recovery of rare and degraded DNA molecules from ancient biological samples, including those of pathogens which can persist in the remains of their hosts for millennia. Here, we will leverage a massive collection of ancient equine DNA (aDNA) libraries spanning more than 50,000 years to investigate the past epidemiological and evolutionary dynamics of DNA viruses in horses and donkeys from the earliest stages of domestication to modern days. An innovative approach will be implemented for the systematic enrichment of viral DNA in aDNA libraries prior to sequencing, to maximize viral detection sensitivity. Metagenomic analyses of resulting datasets will allow characterizing ancient equine viromes and their variations through time. Ancient viral sequences will be used for genomic and phylodynamic analyses to reconstruct past viral genomic changes, geographical spread and transmission dynamics. Inferred patterns will be interpreted in the light of detailed knowledge about horse and donkey's domestication and management history which has been generated in recent years. VIRODOM will provide major insights into the evolutionary history of important equine pathogen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Partial order state and semantics for concurrent logic programming in linear logic' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Research objectives and content There are two parallel main themes of research I want to explore in Nancy. They pertain to a purely logical understanding of computations with structured state in the framework of abstract logic programming. The two threads are intimately related each other.  The first theme is about compositionality of my LES (labelled event structures) semantics for Forum (and linear logic). How does it behaves wrt linear logic connectives? We most probably can obtain compositionality from the structures I already have studied provided we further constrain the language, and this can be done without losing completeness. Having a strong behavioural semantics for linear logic should be of great help in understanding issues pertaining to the second thread of research I propose. The second line of research I want to pursue is about studying and defining abstract logic programming in variants of linear logic, in the same way Miller did with Forum wrt linear logic. In particular I am interested in pomset logic. It is already clear that LES semantics would be perfectly adequate if we had some way to express causality (sequentiality) directly in the language, so I expect to export results I already obtained to the new setting.  Since the general case of pomset logic can be difficult, I propose, in case, to limit this study to the particular case of pomset logic restricted to series-parallel orders. Series-parallel orders should be perfectly adequate to applications.  I am also interested in the definition of abstract logic programming directly on a proof-net syntax. Achievements in this direction would be particularly important, mainly because proof-nets are a much less redundant syntax than sequents. Moreover, in this setting pomset logic could be immediately u
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Nonlinear Approaches for the Design of Active Piezoelectric Metamaterials' under Horizon 2020.

assistant: **Concept**

Mechanical metamaterials have surged to the forefront over the past five years against the backdrop of the unprecedented developments in optical, electromagnetic and acoustic metamaterials. Metamaterials are designer media with periodic units comprised of tailor-made geometry and pattern aimed at accomplishing exceptional bulk properties which are unprecedented in conventional materials. This proposal aims at taking the functionality of metamaterials to the next level by combining mechanical metamaterials with piezoelectrics. This, in turn, will give rise to active metamaterials which can be used for vibration energy harvesting and control. Radically new analytical and computational frameworks will be developed for dynamic homogenization and wave propagation in piezoelectric metamaterials with sub wave-length scale resonators. Linear and nonlinear resonators combined with a multiphysics approach will be adopted. Theoretical models will involve one and two-dimensional metamaterials. Experimental analysis of these models will be carried out at the host institution. This will validate the theoretical results and will also generate new insights. The proposed research inherently depended on ideas from fundamentally different expertise and will be achieved through supervision of three complimentary experts in different institutions and in two EU member of states. The pathway originating from this work will instill the essential confidence to take the leap from scientific curiosity to engineered active mechanical metamaterials. The combination of an outstanding multi-skilled scientific methodology and corresponding bespoke knowledge transfer approach will result in an unprecedented training framework which will result in a transformative impact on the applicant's scientific ca
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'New thermochemical treatment of Titanium parts improving their wear resistant characteristics and their life time' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Titanium has been known as a common element for nearly 200 years and is the fourth most commonly occurring mineral. Nowadays, the major limitation of Titanium use in industry is strongly linked with: - the price of the raw material (between 7 ECU and 8 ECU per kg for a 99,8% sponge of Titanium), - the cost of transformation which requires more than twice as much energy as aluminium or some of the steels. Another drawback of titanium for industrial application is that it usually needs some treatments to enhance its quality and especially its wear resistance and friction properties. These treatments are usually expensive (they double the price of production) which limit their use to high added value parts. The project aims to develop a an innovative thermo chemical treatment of titanium parts (on classical alloy like T40, TA6V, etc. but also on new low cost titanium alloy) by nitrogen diffusion in order to harden the surface. This treatment by nitrogen diffusion will harden the surface and create a thin layer for an increase of wear resistance. The final result should be: - to reduce the cost of the surface treatment (5 to 10 times less expensive) - to increase the wear resistance and thus the lifetime 2 to 3 times - to obtain an homogeneous and penetrating treatment - treatment under low pressure (low environmental impact, low gas consumption), - to treat simultaneously several different and complex shapes - to obtain 100% big compatibility The result of the treatment will be thin layer of TiN and Ti2N + a nitrogen diffusion layer (0,1 mm) with an increase of the wear resistance two to three times more than with usual surface treatment of titanium surface. It will certainly interest a large panel of industrials in various fields coming from medical application to nuts an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Lighting up the dark - the evolution of dust throughout cosmic time' under Horizon 2020.

assistant: **Concept**

After more than two decades of infrared astronomy, we still know very little about the origin and evolution of cosmic dust in galaxies, responsible for obscuring half of all starlight since the Big Bang. This obscured starlight is re-radiated in a region of the electromagnetic spectrum that is still relatively unexplored. Herschel provides a unique opportunity to resolve this by revealing the 90% of dust too cold to be detected before, yet only a tiny fraction of the largest survey of the sky carried out with Herschel has been exploited. This project aims to unravel the dust and gas content of galaxies in the local universe and over cosmic time.  I will produce the first statistical census of dust in galaxies, pushing out to earlier cosmic epochs than previously possible. This also provides us with an opportunity to detect unusual objects not seen in other surveys, including a population of extremely dusty galaxies found in Herschel with blue optical colours and very different properties to more evolved spirals typical of the Milky Way.  I will use our multi-wavelength data to investigate the emissivity, gas and star formation conditions on resolved spatial scales.  Our Herschel data will also expose the role of environment in the interstellar content of early-type and spiral galaxies. I propose a novel approach to resolve the controversy of whether dust forms in exploding stars using polarized light. This could have implications for the detection of polarized signals in the relic radiation from the Big Bang, currently attributed to primordial gravitational waves.  Our polarized dust maps of nearby supernova will reveal whether this could be a major contaminant to cosmological signals. This project is timely due to the availability of final Herschel data products and ne
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'HYbrid sintering and advanced Machining of technical CERamics' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The development of new production processes and innovative sintering technologies, i.e. firing processes during which the conversion of a powder compact into a fully dense bulk compound is realized, as well as the improvement of the current processes and technologies, would permit to enhance the use of ceramics in industrial applications by increased product development and high added value products. This will reinforce the position of the European companies against their competitors in Asia and America. Nowadays, non-conventional machining processes allow cost effective processing of ceramics introducing the possibility to obtain complex 3D shapes. Processes such as vibration assisted and electrical  discharge machining  solve the limitations of conventional processes like grinding, introducing  more flexible and cost effective machining  capabilities.The HYMaCER project, driven by 4 dedicated Hi-Tech SMEs, aims at developing a complete supply chain for large size technical ceramic blanks in order to fulfill their need for economically produced, innovative and difficult to densify technical ceramics, all three parameters which are currently limiting the SMEs’ market expansion.The SMEs will join their knowledge on spark plasma sintering (NANOKER & FCT) and machining of ceramics (Ceratec, ARTOOLING & FCT) to produce innovative technical ceramics with an already proven market potential for dedicated niche markets. In order to realise this, the SMEs will be supported by 3 RTD centres with a long standing expertise in ceramic material development (K.U.Leuven & CSIC), spark plasma sintering (CSIC & K.U. Leuven) and non-conventional machining (K.U.Leuven & IK4-TEKNIKER).The research will be focused on the fabrication  of electrically conductive technical ceramics, combining
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Assessment Methodologies for ICT in multimodal transport from User Behaviour to CO2 reduction'.

assistant: **Objectives**

The AMITRAN project will develop a framework for the evaluation of the effects of ICT measures in traffic and transport on energy efficiency and CO2 emissions. By doing so, it will contribute to the development of ICT solutions that allow more efficient multimodal goods transport and passenger mobility. It is AMITRAN's ambition to build the foundations for a standardised assessment of future European ICT developments.<br/>Earlier studies indicate possible CO2 reductions up to 25% with certain ICT measures. AMITRAN provides the methodology and tools to assess such reductions on European level in a systematic and realistic way. This will support developers, public authorities and investors in ICT solutions to make sound decisions based on reliable impact estimates, covering the complete transport chain.<br/>AMITRAN's objectives are:\tDeveloping a CO2 assessment methodology for ICT measures including multimodal passenger and freight transport, taking into account the whole chain of effects from user behaviour to CO2 production\tDeveloping open interfaces for models and simulation tools implementing this methodology starting from the road sector and integrating high level modelling from the other modes\tDeveloping a generic scaling up methodology and publicly available knowledge base with statistics to translate local effects to EU level.\tValidating the proposed methodology and its implementation with reference implementations using available data from other projects and/or studies\tProducing an online checklist and online guidance tool for future projects to use the proposed methodology in a practical manner<br/>The top of EU transport R&D institutes have bundled forces to cooperate in AMITRAN. There will be cooperation with recent and ongoing EU projects where ICT a