RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Experimentation and Validation Openness for Long-term evolution of VErtical inDustries in 5G era and beyond' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The intense ongoing work towards 5G readiness has reached the point where the performance gains provided by 5G infrastructures should be exploited by third party innovators and SMEs, to create a new, open and dynamic ecosystem from both technology and marketing perspectives. Towards the materialization of the 5G performance gains at application and market level, key contributions are expected by the domain of design and development of Network Application (NetApp). In this context, EVOLVED-5G endorses the vision where the world of NetApps follows the paradigm of mobile applications hosted in a related market place. Moreover, the EVOLVED-5G project will contribute towards the fourth industrial revolution or Industry 4.0. Recognized as one of the major vertical industries by 5G-PPP (referring to the digital evolving of workspaces), Industry 4.0 brings innovative use cases, yet technologically challenging, and create a fertile environment for SME-driven entrepreneurship, where new use case-tailored functions (as NetApps) can be provided to compose a digitalized, secure, and automated generation of the industrial operations (mainly referring to functions for process and machine control as well as procedures for advanced product lifecycle management). The industry-oriented EVOLVED-5G NetApps will be tested, validated, and certified in a vendor-agnostic experimentation platform, and progressively define the first set of NetApps that the EVOLVED-5G marketplace will host.


**Keywords:** 5G, Industry 4.0, NetApp, Network Programmability, multi-domain orchestration, CAPIF, SEAL, TSN, SDK, marketplace
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Development of mass spectrometric methods for the study of protein-nucleic acid interaction sites' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

The proposed project combines mass spectrometry with already established techniques for protein interaction study, i.e. foot printing" and "cross linking" in order to simplify and accelerate the characterisation of protein-nucleic acid inter- actions. Two ionisation methods, matrix assisted laser desorp- tion/ionisation (MALDI) and electrospray ionisation (ESI) have recently significantly improved the possibilities for mass spectrometrlc analysis of these biomolecules. High sensitivity (femtomoles) and short analysis time (some minutes) of these techniques have the potential to significantly improve the presently used methods for the study of interaction sites of proteins and nucleic acids. Accurate mass determination and fragment-ion studies in combination with specific chemical and biochemical degradation and modification reactions will be used to generate the needed structure information. Computer assisted combination of these data with information available in sequence data bases (mass spectrometric data as search criteria) will be the final step for the identification of the interaction sites in the participating biopolymers."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Fossil Fingerprinting and Identification of New Denisovan remains from Pleistocene Asia' (FINDER) under Horizon 2020.

assistant: **Objectives**

Scientific analyses of ancient biomolecules (proteins, DNA, hard tissues) have transformed our knowledge of archaic hominins present in Eurasia prior to the expansion of modern humans from Africa. In 2010, a finger bone discovered in Siberia was assigned using DNA to a new, previously unknown human group, the Denisovans. The Denisovans interbred with both Asian Neanderthals and AMH over the past 100,000 years; their geographic distribution is now thought to have stretched from the Siberian steppes to the tropical forests of SE Asia and Oceania.Despite their broad spatio-temporal range, the Denisovans are only known from 4 tiny bones, all from a single Siberian cave. This patchy knowledge of an entire human population significantly limits our ability to test hypotheses and interpretative models concerning major issues in human evolution, such as the routes and timing of people movements across Asia, the nature and frequency of interaction between archaic indigenous groups and migratory modern humans, the mechanisms leading to the demise of archaic lineages and eventual sole dominance of our species on Earth.This project aims to rectify the dearth of Denisovan fossils by applying a novel combination of cutting-edge scientific methods (collagen fingerprinting, radiocarbon dating and ancient DNA analyses) designed to identify, date and genetically characterize new human fossils, with a particular emphasis on the discovery of Denisovan remains. Instead of only focusing on the few morphologically identifiable human bones, a groundbreaking high-throughput approach will target bulk collections of unidentified bone fragments (n=30,000) from ~20 Asian sites dating to between 100,000-10,000 years.Ultimately, the goal is to expand our understanding of the Denisovans, reveal their g
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Interstellar dust in star forming regions of nearby galaxies' under Seventh Framework.

assistant: **Concept**

Understanding the formation and evolution of a galaxy requires the knowledge of the properties of its stellar population and its star formation activity. The presence of dust in the interstellar medium is fundamental in the star formation process, and is a by-product of that process, which makes the dust itself a tracer of the star formation rate within galaxies. The interstellar dust absorbs the ultraviolet (UV) radiation coming from the stars and re-emits it in the infrared (IR).  The correction for dust extinction is the main source of uncertainty in the estimation of important characteristics of entire galaxies. The research project has the primary goal of studying the role of interstellar dust in nearby star-forming regions. We will study the physical properties of the dust and how they are affected by its stellar environment, the contribution of the dust to the kinematics of the gas in star-forming regions and the confidence in the use of dust emission as a component tracer of the star formation rate in galaxies. We will use data from SPITZER, which provides mid-IR data at the best available resolution, combined with multiwavelength observations (UV-optical-CO-HI), and Fabry-Perot interferometry, one of the most powerful techniques for studying the kinematics of the interstellar gas. The proposal will lay the groundwork for my participation in the scientific exploitation of the forthcoming IR space telescopes, PLANCK and HERSCHEL, to be launched by the European Space Agency in 2008. They will provide observations in a broader wavelength range than currently available and will contribute to a deeper knowledge of the role of the interstellar dust within star forming regions. My stay in Cambridge will be the best possible preparation for the efficient use of the data
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Genomic Approach to Study the Role of Bacterioplankton in the Sulfur Cycle', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

This proposal aims at using environmental functional genomic tools to expand knowledge of bacterial roles in organic sulfur cycling in ocean surface waters, focusing particularly on biological controls of volatile sulfur exchange across the ocean/atmosphere boundary and links between microbial community structure and cycling of relevant organic sulfur compounds. A better understanding of the fate of dimethylsulfoniopropionate (DMSP), the precursor of the climatic active gas dimethylsulfide (DMS) in marine environments will not only provide insights into climate regulation and ocean-atmosphere interactions but also microbial food web dynamics and C and S biogeochemistry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Competitive Eschatologies: Eastern Christianity and Islamic Apocalypticism'.

assistant: **Innovation**

CESECIA (Competitive Eschatologies: Eastern Christianity and Islamic Apocalypticism) is an interdisciplinary project exploring the shared yet contested apocalyptic imagination of the eastern Mediterranean between the 7th and 13th centuries. It examines how eschatological narratives – written in Islamic Arabic, Christian Arabic, Syriac, and Greek – shaped interreligious relations and communal identities. The project hypothesizes that apocalyptic expectation functioned as a strategic cultural resource for interpreting crises, directing political action, shaping communal identity, and framing the religious “Other.” CESECIA pioneers critical editions and translations of understudied Arabic Christian apocalyptic texts, including the Arabic Apocalypse of Pseudo-Methodius and the Arabic Apocalypse of Peter, making them accessible through open-access publication. By combining philological rigor with cross-cultural analysis, the project reconceptualizes apocalyptic texts as co-produced, multilingual traditions that served as dynamic instruments of historical agency. Beyond medieval studies, CESECIA highlights the enduring relevance of apocalyptic thought for understanding uncertainty, imagining the future, and fostering reflection on interreligious and intercultural connections in pluralistic societies such as those in Europe.


**Keywords:** Eschatology; Apocalypticism; Eastern Christianity; Islamic thought; Messianism; Comparative religion; Cultural Encounters
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Towards Safe and Effective Hematopoietic Stem Cell Gene Therapy: Targeting Integration to Genomic Safe Harbors and Exploiting Endogenous microRNA to Regulate Transgene Expression' (TARGETINGGENETHERAPY).

assistant: **Innovation**

Hematopoietic stem cell gene therapy has a tremendous potential to treat human disease. Yet, in conjunction with the first successful results in the clinic, severe adverse events linked to the gene transfer protocol were reported. Recently, we provided proof-of-principle of two new powerful strategies to improve the efficacy and safety of gene transfer: 1) regulating transgene expression by exploiting cellular microRNAs; 2) targeting integration at predetermined sites of the genome by forcing homologous recombination with designer Zinc finger nucleases. Here we will investigate the microRNA network regulating hematopoiesis and exploit the new knowledge to develop vectors with stringently controlled expression throughout the hematopoietic lineages. We will develop Zinc finger nuclease-based vectors that insert the transgene with high efficiency and specificity either downstream to its own endogenous promoter or into a safe genomic harbor that allows for robust expression without interference on the neighboring genes. By combining these strategies we will provide radically improved gene transfer platforms. Furthermore, we will exploit these technologies for the generation and genetic correction of induced pluripotent stem cells, providing a potentially unlimited source of patient-derived vector free gene corrected multipotent stem cells for future applications of regenerative medicine. The new gene therapy strategies will be tested in pre-clinical models of leukodystrophies and immunodeficiencies, for which we have extensive experience, and should enter a clinical trial for at least one such disease by the end of the proposed funding period. If successfully validated, the new strategies may eventually broaden the scope of gene therapy in medicine.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Role of the parietal lobe in episodic memory retrieval' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

Previous studies have provided strong evidence that medial temporal lobe is crucial for episodic memory. However, recent functional magnetic resonance imaging (fMRI) studies show larger posterior parietal activations for recognized items than for new items, suggesting that this brain area may play a role in episodic retrieval.The aim of the research project is to investigate the role of the posterior parietal cortex in episodic memory retrieval. We propose that the posterior parietal cortex might be involve d in orienting attention to the recovered memories, accessing memories from different points of view, and reinstating at retrieval the multisensory activity present at encoding.These hypotheses will be tested in 5 experiments. We will integrate behaviour al evidence on healthy people, lesion studies, and fMRI evidence. The outgoing phase will be conducted at the Rotman Research Institute, Toronto under the supervision of Morris Moscovitch, and will last 2 years.The return phase will be conducted at the Centro Studie Ricerche in Neuroscienze Cognitive, Cesena, under the supervision of Elisabetta Ladavas, and will last 1 year. The training at the Rotman Research Institute will help the researcher to become an expert in the cognitive neuroscience of memory, and in fMRI. This gained expertise will be then applied by the researcher to continue the project in the return host organization.The opportunity to work with American colleagues would contribute to create the basis for future international collaborations, and to enhance European scientific excellence in memory research. In particular, memory research is incredibly neglected in Italy.Thus, learning about memory and fMRI techniques will be extremely helpful to the future re-establishment of the researcher in Italian i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Production of low cost, high efficiency Alkaline fuel cells with silver electrodes using advanced production techniques' (1994-1998).

assistant: **Concept**

The Zevco technology allows the production of Alkaline Fuel Cells on an industrial scale. The proposed programme aims at both: - increasing the efficiency of the fuel cells, - reducing the cost by replacing Platinum (Pt) with Silver(Ag) as the catalyst in the cathode and by introducing an alternative current collector. Work will include screening/adapting Ag-catalyst materials and current collectors for efficiency and for compatibility with the existing manufacturing technology and optimising manufacturing parameters to achieve a new electrode concept at industrial level.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'MOnItoRing of large scale complex technologicAl systems'.

assistant: **Objectives**

Modern technological systems increase in scale and are becoming more and more complex and sophisticated. Parallel, the revolution in electronics, digital technology and communications have drastically modified and expanded the physical diversity, scope, processing capabilities and complexity of the monitoring equipment and infrastructure used. Millions of networked sensors are being embedded in the physical world sensing, creating and communicating data. The amount of data available for capturing has been exploding and the era of Big Data is already here, as the Internet of Things (IoT) is becoming a reality. The main question which arises is how, following which steps and with which tools the data can be transformed to information and knowledge. The objectives of MOIRA are i) the development of novel signal processing tools for the monitoring of industrial processes based on machine learning methods applied on heterogeneous time series, ii) the application of data mining technologies for the estimation of Key Performance Indicators which determine the operational profit, iii) the conception, development and validation of methodologies for automated monitoring of cyber physical system fleets, iv) the multi sensor machine condition monitoring under variable operating conditions. The proposed MOIRA project (MOnItoRing of large scale complex technologicAl systems) brings together early stage researchers and experienced specialists from key players in academia and industry across Europe covering different scientific disciplines and industrial stakeholders from a broad range of backgrounds to optimally tackle the challenges ahead. The MOIRA Fellows will be trained in innovative PhD topics as well as receiving specific theoretical and practical education in the fields of mech
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Mesoscale two-photon imaging of astrocytic calcium dynamics and neuromodulation during multisensory perception' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

To build a coherent representation of the world, the brain combines inputs from different sensory modalities in a process named multisensory integration. Multisensory processing involves computations distributed across brain areas and cell types and it is profoundly shaped by neuromodulation. Correct perception of our multisensory environment is highly beneficial for survival as it enables accurate responses to external stimuli. Sensory neocortical areas continuously encode, integrate and elaborate multisensory information even at the primary sensory level. In these areas, multisensory neurons respond to multimodal stimuli aligned in time and space. Astrocytes integrate signals coming from neuronal populations. In turn, astrocytes can modulate neuronal activity. These cells are thus ideally placed to integrate and mediate multisensory information. Yet, if astrocytes regulate sensory perception is unclear. Additionally, due to technical limitations, most studies of multisensory processing focused on single areas separately. With this project, I will reveal the role of astrocytes in encoding multisensory stimuli across sensory areas. This will be achieved by performing, for the first time, two-photon mesoscopic imaging on both neurons and astrocytes. With advanced computational methods, I aim to decipher if information about multisensory perceptual behaviour encoded by astrocytes is complementary to that in neurons. Additionally, stimulus detection relies on external input, but is also influenced by internal states, such as attention. Acetylcholine (ACh) is correlated with attention and affects neuronal circuit responses. Hence, I will test if astrocytes are behavioural state regulators by investigating if ACh release correlates with astrocytic responses during task engag