RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Sustainable and Integrated people centRiC solUtions for buiLding decArbonisation and circularity'.

assistant: **Innovation**

SIRCULAR intends to create digital tools, technological solutions and non-technical services for the decarbonisation of the built environment, as well as a ready-to-use methodology for assessing the circularity of a given building capable of evaluating the impact of the developed construction technologies in the demos. These features are intended to improve access to information on decarbonisation for end users who are not experts in these fields, as well as to provide professionals working in the construction sector with tools capable of easily evaluating and improving the circularity of this area. The SIRCULAR solutions will take a multidisciplinary approach, integrating technical, economic, and social approaches with a focus on social and policy innovation, delivering valuable information to policymakers and establishing a solid foundation for the promotion of developed decarbonisation methods. The project will also be distinguished by an overall people-centric approach that prioritizes the needs, ambitions, and well-being of individuals and communities as critical players in the decarbonization of the construction industry. SIRCULAR will prioritize active participation, inclusion, and ethical concerns to ensure that the project's achievements directly benefit society as a whole. The project will also make special efforts to engage the whole supply chain engaged in all phases of the building's life cycle, with the goal of increasing the circularity and sustainability of each of them. SIRCULAR plans to consider four national clusters to promote a circular and sustainable construction sector using a value chain approach. The clusters will focus on Estonia and Spain, followed by Germany and Greece. The clusters will involve construction companies, housing companies, uni
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Particle-Surface Interactions in Near Field Optics: Spin-orbit Effects of Light and Optical/Casimir Forces' to be submitted under Horizon 2020.

assistant: **Abstract**

PSINFONI aims to open new avenues of research in ultrafast routing and polarization synthesis of light in nanophotonics, and in the manipulation, sorting, levitation and trapping of nanoparticles, molecules, or single atoms near novel nanomaterial surfaces. To this end, we will explore the fundamentals and applications of a range of novel nanophotonic phenomena: (i) spin-orbit interactions of light for polarization-controlled optical routing and polarization synthesis at the nanoscale; (ii) repulsive and switchable lateral optical forces on particles near engineered surfaces for optical manipulation and sorting; and (iii) Casimir repulsive and lateral forces for quantum levitation / frictionless nanomaterials. All these diverse phenomena can be studied under the single framework of particle-surface interactions in the near field, greatly diversifying the research outcomes from a single research effort. Knowledge of the full 3D electromagnetic fields in particle-surface systems will form the foundation from which to explore fundamental aspects and limitations of the above mentioned effects, opening new applications in information technologies and new nanomaterials. Proof of principle experimental demonstrations will be performed where possible.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Relative positioning of mobile objects in ad hoc Networks'.

assistant: **Objectives**

Positioning of mobile devices and objects is a core problem in emerging computing systems, such as wireless sensor networks and ubiquitous computing environments. Most commonly this problem is addressed with external infrastructure installed in the system's environment to acquire and manage position and location information. This project, in contrast, will investigate relative positioning of mobile objects to determine their spatial arrangement free of surrounding infrastructure.We propose an approach wherein spontaneously networked mobile objects perform collaborative sensing and communication to collectively determine their relative positions and spatial arrangement. The project will engage with the fundamental research challenges that such an approach implies: how to obtain relative position in ad hoc systems, how to reason about dynamic spatial arrangements, and how to provide application support across different domains. Our research method is experimental systems engineering: building and deploying prototype systems for application experiments in the real world.Relative positioning enables a wide range of applications with largely varying requirements. We assume that there is no 'single best' technology option and will assess a range of candidate technologies with respect to factors such as accuracy, robustness, scalability, cost, and fitness for different application settings. This is complemented with application-driven investigation focussed on three concrete settings: environmental sensor networks, indoor spatial awareness, and multi-device interactive systems.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Evolution of plant disease resistance genes', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

To analyse the natural variation at a disease resistance gene locus in Arabidopsis. The chromosome 4 locus specifying resistance to the Peronospora parasitica isolate Cala2 will be examined in a large number of host accessions. Resistance genes from two accessions will be sequenced and compared to determine the degree of sequence divergence that occurs between functional alleles. Additionalyy, the corresponding susceptibility loci will be sequenced and compared. Current evidence is that susceptibility is caused by loss of the gene, but non-functional structural homologues could exist in other accessions. The universality of this observation will be tested and the loci sequenced. Analysis of the deleted regions could reveal the cause of this genomic instability. Sequence analysis of non-functional homologues will reveal the structures that are essential for recognition of the Cala2 pathogen isolate. Finally, the project will reveal the current evolutionary state of this gene locus in 100 UK accessions of Arabidopsis and give clues as to its stability in natural plant populations. To become familiar with the techniques involved in the molecular and classical analysis of disease resistance genes. This will envable me to assess strategies for manipulating disease resistance in crop plants. All these skills be useful to me in my future research career in Greece.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'LeukoBIAS: Analysis, mitigation, and auditing of bias in foundation model-based leukemia detection from routine diagnostic blood smears', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Foundation models have revolutionized image processing in healthcare, offering robust performance across various tasks without task-specific training. However, potential biases in these models, especially when applied to critical medical diagnostics such as leukemia detection, remain largely unexplored. LeukoBIAS aims to address this crucial gap by developing a framework for analyzing and mitigating bias in foundation model-based leukemia detection algorithms.Building on my previous work in AI-driven leukemia diagnostics, we will leverage a unique real-world dataset of over 6000 patients from my long-time industry partner, the Munich Leukemia Laboratory, to investigate biases related to sex, age, and other patient characteristics. Our approach combines advanced machine learning techniques, including multiple instance learning and attention mechanisms, with novel bias detection and mitigation strategies.The project consists of three work packages: (i) bias analysis in foundation model-based leukemia diagnostics; (ii) development of bias mitigation techniques for model fine-tuning; and (iii) exploration of intellectual property and commercialization opportunities for bias auditing.The innovative potential of the project extends beyond leukemia diagnostics. We will thus explore the scalability of our approach to other modalities and conduct a comprehensive market analysis to identify potential industry partners. LeukoBIAS will contribute to the scientific understanding of bias in medical AI and pave the way for more equitable and reliable AI-driven diagnostic tools. By addressing the requirements outlined in the EU Artificial Intelligence Act, LeukoBIAS is poised to have a significant impact on the development and deployment of trustworthy AI in healthcare. By providing a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'MAUVE - A UV satellite for space science' (MAUVE).

assistant: **Innovation**

We propose building a ready to launch Cubesat (MAUVE) optimised for the observation of stars in the Ultra Violet (UV) spectral window. MAUVE will be designed and built by a consortium of space focused SMEs, and will be capable of observing over tens of different stars during its expected lifetime of 3 years, enabling studies of stellar flaring activity and exoplanet habitability. The MAUVE program will demonstrate the potential for cubesats to deliver data to the astronomical and planetary community that complement and enhance the outputs of science satellites built by ESA and other space agencies. Our Cubesat will move from TRL3 to TRL 6 within this project and will prove a 16U configuration for delivering excellent science data, while developing the key technologies in the interface with the detector, the thermal design and high performance pointing accuracy.  The project and its subsequent development is based on the basic philosophy underpinning delivery of Space 4.0 capabilities in Europe, the establishment of private-public partnerships, with a unique commercial approach to space science data delivery, building a global community of scientists with European leadership. The delivery of such a complete system on such a condensed timescale will be a breakthrough in the technology available to the space community, enabling a new era of space research and exploration.


**Keywords:** space technology, cubesat, uv optics, space 4.0, commercial space, NewSpace
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Complex dynamics' (1994-1998) under Fourth Framework.

assistant: **Objectives**

Research objectives and content The overall objective is to better understand the pure mathematics underlying universal phenomena in non-linear systems, and the particular target of the project is to develop and extend the theory of iterated correspondences on the Riemann sphere. With the aim of uniting and generalising the existing theories for rational maps and Kleinian groups. Training content (objective, benefit and expected impact) The proposed research will involve both, development of pure mathematical theory (using techniques of complex analysis hyperbolic geometry and symbolic dynamics) and computer experimentation. Links with industry / industrial relevance (22) The research will lead to a better understanding of chaotic phenomena and the control of non-linear processes and therefore is of long-term interest to industry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'European cancer immunology and immunotherapy summer school (EURO-CISS)'.

assistant: **Concept**

The basic principles underlying tumour immunology have evolved considerably. It has been established that :(1) the normal immune system is rarely a significant barrier to tumour growth, (2) most tumours are antigenic but few spontaneous tumours are immunogenic and (3) manipulation of the immune system can result in complete tumour eradication. Although the first two principles are well established, the third has been shown in only a few cases so far. In fact, immunotherapy often fails or is otherwise inadequate even in the presence of a potent immune response. It is therefore crucial to probe (1) which properties of the immune system contribute to poor immunogenicity and how the this property can be stimulated and (2) how cancer cells present tumour-related barriers to immunotherapy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Land-use change and the resilience of food production systems (LucFRes)' (LucFRes).

assistant: **Concept**

Securing food production remains a critical challenge in many world regions. Environmental change, in particular land-use change, constrains food production especially in contexts characterised by competing land demands, high population pressure and food insecurity that got compounded by the COVID-19 pandemic. Land-use change has long-term impacts through land degradation which affects food production systems (FPSs). Hence, an understanding of how changing land-uses shape the resilience of FPSs is therefore urgently needed to enhance agriculture’s adaptation. LucFRes aims to examine the processes operating at the interface of agricultural land-use and food production. Agricultural land-use change will be characterised in terms of the change intensities and the driving factors using Intensity Analysis, a spatially explicit, land change accounting framework. Relevant land-based resilience indicators for FPSs will be identified and validated with stakeholders for Southwest Nigeria. The combination of the satellite remote sensing-based land-use change intensities with stakeholders’ perspectives of likely land-use changes will provide the empirical-basis for modelling FPSs behaviour under changing policy and land management scenarios. To better optimise agricultural land-use change, the modelling will account for trade-offs and options for enhancing synergies between food production and other land uses. Thematically, LucFRes goes beyond the impacts of land-use on agricultural productivity by examining how changes in agricultural land-use build or undermine the resilience of food production systems in Southwest Nigeria, an area that have received little research attention. LucFRes’ integrative and policy-oriented approach will develop trajectories for enhancing the resilience
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Bio-sustainable production of natural medicines from Vitex' (MediVAC).

assistant: **Innovation**

Vitex agnus-castus (VAC) is a medicinal plant clinically shown to be an effective treatment for premenstrual syndrome. The bioactive constituents are diterpenoids that can interact with G-protein-coupled receptors such as the dopamine D2 and D3 receptors. This specific activity also opens up the possibility of other therapeutic applications where dopaminergic drugs are required, such as for the treatment of Parkinson’s disease and other movement disorders. The major barrier to the development of VAC diterpenoid drugs, and the further exploration of pharmacological activity of VAC diterpenoids, is the lack of a source of pure compounds. MediVAC is a 24 month research project that will discover the genes involved in the biosynthesis of pharmacologically active diterpenoids in VAC, and to express these genes in a biotechnological platform for the sustainable production of pure bioactive diterpenoids. State-of-the-art imaging mass spectrometry tools will be used to identify diterpenoid rich tissues which will be targeted for transcriptomics. Then, through the integration of bioinformatic, molecular biology and analytical chemistry techniques, the diterpene synthases and cytochrome P450 enzymes involved in VAC diterpenoid biosynthesis will be identified and functionally characterised. The resulting molecular toolbox of diterpenoid genes will be stably integrated into yeast for the production of bioactive diterpenoids. The engineered host strains hold potential for the future development of an industrial scale production platform able to produce high-purity, bioactive diterpenoids for the pharmaceutical industry. Implementation of this proposal will provide the research fellow with essential training in the field of molecular biology and further her plant metabolic profiling
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The Physics and Applications of Magnetic Guiding of Fast Electrons through Structured Targets' under Seventh Framework.

assistant: **Concept**

When ultra-intense lasers interact with matter, extreme conditions are produced which cannot normally be accessed in terrestrial laboratories.  These extreme states of temperature, density, and pressure form the basis for laser fusion, compact particle accelerators, and well as the exploration of the cosmos through scaled laboratory experiments of astrophysical phenomena.One feature of ultra-intense laser-solid interactions is the absorption of energy into high current relativistic electron beams.  If the flow or propagation of these beams through dense matter could be controlled then many new possibilities in laser fusion and other areas of high energy density physics would emerge.  Detailed control of  fast electron propagation has not usually been seen as possible due to the short time-scales and small spatial scales.In previous work the PI showed that detailed control of fast electron flow might in fact be possible by using structured targets, where a guide path is defined by a more resistive material than the bulk material.  Fast electron flow will then lead to resistive self-generation of magnetic field around this region which is strong enough to confine and guide the fast electrons along this path.Although promising, this concept still needs much work, and in particular physics relevant to longer (i.e. multi-ps) time-scales need to be included.  In this project we will develop a numerical tool that incorporates all the relevant physics, use this to elucidate the important physics of the multi-ps regime, and then use this knowledge for Fast Ignition inertial fusion and other high energy density physics applications.