RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Functional genomics of human neurocristopathies: application to hischprung disease', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

It is with great pleasure that I write a recommendation for Dr. Yolanda Espinosa Parrilla. Since January 1995 till July 2000, when she successfully defended her Ph.D. thesis, she has been working as a PhD student under my supervision in the Thrombophilia laboratory of the Medical and Molecular Genetics Center -IRO. The research project she was given when she arrived was the analysis of the molecular pathology associated with different type of inherited protein S deficiency and venous thromboembolic disease. After a short time in the laboratory it was clear to me that Yolanda had the aptitudes required to become a good scientist. She immediately grasped the concept of the research project and rapidly determined what was required for its successful implementation. Through her Ph D work, Yolanda Espinosa has obtained a good experience in molecular genetics analysis and, particularly, in mutation detection by different methodologies( DNA sequencing, transcript analysis, site directed mutagenesis and recombinant protein expression analysis. Apart from the PROS1 gene, she has also analysed the contribution of additional inherited risk factors for thrombosis in the development of the clinical phenotype of the PS deficient individuals she analysed, which has provided new insights on the complexity of venous thrombotic disease. As a result of her excellent aptitudes, as well as her rigorous and constant work, after five years of training and research in human molecular genetics, Yolanda Espinosa has made a first rate Ph.D. with significant contributions to the molecular genetics of thrombophilia and, more specifically, to the relationship between protein S gene mutations, protein S deficiency and thrombosis. On this subject, she is the first author of two Blood, one Thrombosis a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Biological properties of the pml-associated nuclear bodies involved in acute promyelocytic leukaemia' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

Acute promyelocytic leukaemia (APL), a disease caused by a block in promyelocyte differentiation. is associated with a t(15:17) chromosomal translocation resulting in the production of a hybrid protein, PML-RARa. which consists of a nuclear factor, PML. fused to the retinoic acid receptor a (RARa). The differentiation block is relieved by all-trans retinoic acid (RA), the activating ligand of RARa. Recently it was shown that PML is localized in distinct nuclear bodies and that PML-RARa causes disruption of these bodies together with PML s delocalization into aberrant matrix associated nuclear structures. Treatment of APL cells with RA induces a complete relocalization of PML and restores nuclear bodies. Thus the beneficial role of RA in APL might be related to its ability to restore a normal subnuclear organization. To characterize the normal function of PML-containing nuclear bodies, the major aim of the proposed work is to identify other proteins of these structures. Recombinant PML, ND/SP 100 -another protein component of nuclear bodies- and adenovirus E4ORF 3 products -also interacting with nuclear bodies- will be used as probes for the screening of an expression library to identify proteins interacting with PML. NDtSP 100 or E40RF 3. A yeast interaction trap/two-hybrid system, where PML. ND/SP 100 and E40RF 3 will serve as the bait" proteins, provides an alternative tool to isolate associated proteins."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Impact of Transport Infrastructure on International Competitiveness of Europe' (I-C-EU), addressing dissemination and exploitation.

assistant: **Impact**

The transition process between the Lisbon Agenda and the Europe 2000 strategy plans happens exactly in the time when Europe is undergoing its hardest economic crisis since its formation. The objective of getting out of the crisis together with the urgent need to remains performance in the context of fiercer world economic competition especially against the new emerging economies has made Europe’s competitiveness and economic performance fundamental issues.White Paper 2011 has summarized the main objective of European transport strategy which is to help establish a system that underpins European economic progress, enhances competitiveness and offers high quality mobility services while using resources more efficiently.In this sense, it is essential then first to clarify the relationship between the transport sector, economic growth and competitiveness and second, to elaborate a working framework so that transport policy intervention can effectively improve European economic growth and competitiveness.The I-C-EU will be a project that clarifies the relationship between transport infrastructure investment and its wider economic impacts, namely competitiveness and economic growth in particular. This clarification will be made possible by exploring the state-of-the-art of the theoretical methodology of the assessment tools, analysing current and future situation of Europe while taking into account European strategy on growth and competitiveness. Using this triad of concept will allow I-C-EU to provide recommendations to the European Commission on making political intervention in order to enhance competitiveness of Europe.The I-C-EU Project has set a strategy based on six Work Packages to achieve all the above objectives. The consortium of six academic and research institutes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Printable, organic and large-area realisation of integrated circuits' under Seventh Framework.

assistant: **Concept**

The objective of the project is to realise high-performance organic electronic devices and circuits using large-area processing compatible fabrication methods. The high performance of the organic circuits referred to here means high speed (kHz-MHz range), low parasitic capacitance, low operating voltage, and low power consumption. The related organic thin film transistor (OTFT) fabrication development will be focused to enable a high resolution nanoimprinting lithography (NIL) step, which is compatible with roll-to-roll processing environment. Applying NIL will enable smaller transistor channel lengths (down below 1 µm) and thereby an increase in the speed of the device. Another important concept to improve the performance is the self-aligned fabrication principle, in which the critical patterns of the different OTFT layers are automatically aligned in respect to each other during the fabrication. This decreases the parasitic capacitances and thereby increases the speed of the device, and is one of the key elements to enable the use of large-area fabrication techniques such as printing. Also complementary transistor technology will be developed, which will enable a decrease in operating voltage and power consumption. The high performance organic transistors will be tested in basic electronic building blocks such as inverters and ring oscillators. The technology development will be exploited in the active matrix liquid crystal display (AMLCD) and radio-frequency identification (RFID) demonstrators. In addition to showing that sufficient performance can be reached without sacrificing the mass fabrication approach, solutions for the fabrication of roll-to-roll tools in order to make serial replication viable will be provided. Finally, the design, characterization, and mode
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'A novel Wireless, wearable Shoe-based system for real time monitoring of Energy Expenditure and Gait parameters for Sport and Medical Applications' in the context of a Seventh Framework call.

assistant: **Objectives**

Gait parameters monitoring and energetic expenditure (EE) calculation is of high importance for patients recovering from diseases that affect movement (e.g. stroke). The same applies to professional athletes either in the phase of recovery from a lower limb injury or performing a sport requiring precise body posture and movement control. Currently, gait parameters’ monitoring is made either using the physicians experience or specialised equipment that, apart from being expensive, requires the subject to wear a belt with a data acquisition system and cables running on his legs. The Wi-Shoe project aims in the development of a completely non-invasive wearable shoe-based system for measuring gait parameters and EE during walking. The system to be developed integrates miniature sensors in a custom designed sole for different shoe types. The project answers the actual need of the rehabilitation and sport sectors for a person-centric product that will allow continuous monitoring of the subject without an expert’s intervention, promoting the role of “home as care environment”. Data from the shoes is sent to a nearby Personal Device (e.g. Smartphone) for immediate basic analysis and warning generation. Data can be afterwards sent through a cloud application to a sector expert where novel analysis models are used to evaluate the subject’s status and performance. The SME participants will obtain the advantage of using and trading a unique product with clear benefits for rehabilitation and sport centres and most importantly for the end users (patients, athletes). The system will address key challenges faced by the SMEs: minimize the need for continuous expert assistance and consequently cost; improve the patient’s sense of independence; assist the expert in acquiring critical info
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Formation of Black Hole Mergers in Dense Stellar Systems' (BlackHoleMergers) targeting Horizon 2020.

assistant: **Abstract**

The recent pioneering observations of gravitational waves (GWs) from merging black holes (BHs) by LIGO/Virgo have already led to new remarkable insight: From the first few events we have learned that BHs do indeed exist, that Einstein's General Relativity (GR) seems to very well describe their merger and ring-down evolution, and that nature is able to pair BHs in compact binary systems. However, many astrophysical key questions still remain unsolved, including, how and where BHs form and what helps them to get close enough to merge on an observable timescale. The project I propose will provide new state-of-the-art insight into such fundamental questions by addressing how BBHs form and merge in dense stellar systems, as well as how well one can infer their origin from their emitted GW signal. In order to achieve this goal, I will develop a new numerical Monte-Carlo framework for evolving dense stellar systems, which for the first time will include: stellar tidal interactions and GR corrections during strong few-body scatterings, orbital diffusion from weak encounters, and secular effects near a possible central massive BH. From my recent analytical models, these effects are expected to lead to the formation of eccentric BBH mergers, as well as other exotic populations, all of which can be used to constrain the dynamical origins of BBHs. The goal is to provide the community with accurate BBH merger distributions that can be used to constrain the origin of BBH mergers using incoming data from LIGO/Virgo. I will carry out the project at the Niels Bohr Institute under the supervisions of Prof. Martin Pessah and Niels Bohr Prof. Enrico Ramirez-Ruiz. The interdisciplinary environment, vibrant atmosphere, and exceptional scientists make the Niels Bohr Institute not only the ide
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Cell-Based Models for Neurodegeneration Study and Use in Screening' under Horizon 2020.

assistant: **Concept**

1.Treatment of neurodegenerative disease is an unmet clinical challenge and patient care is a growing, unsustainable global healthcare burden. The project will produce novel tools to address this challenge.2.The consortium will deliver a set of innovative analytical tools for neurodegenerative drug discovery using a combination of stem cell biology and novel biomaterials assembled by additive manufacturing.3.The toolset will be analytical kits containing induced pluripotent stem cell (iPSC)-derived human neural cells in 3D culture formats, delivered to end-users in multiwell plates ready for industrial screening.4.Project outputs will be realised by an inter-disciplinary consortium of four SME commercial partners in three European countries, each partner supplying a specific, essential skillset.5.iPSC-derived neural cells will be produced by Phenocell sarl (F) using stem cell differentiation protocols already shown to generate glial or neuronal cell lineages, and to reinstate donor disease phenotypes.6.Bio-printer instrumentation and printable bio-inks to manufacture 3D scaffolds enabling 3D cell culture will be contributed by Cellink (SE).7.3D culture models will be customised for neural/neurodegenerative cell culture by inclusion of peptide dendrons with biological functionality using mature chemistry proprietary to Tissue Click Ltd (UK).8.Cell-based analysis products will be validated, and made user-friendly by in situ cell cryopreservation and analytical processes familiar to AvantiCell Science Ltd (UK).9.Each contributing technology is at TRL 6, and each has commercial utility in simpler combinations. The project assembles them in first-to-market formats beyond the current state of the art. 10.The CENSUS project output, comprising iPSC-derived neural cells cryopres
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Climates of Listening: Amplifying Pacific Experiences of Environmental Crisis', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Climates of Listening: Amplifying Pacific Experiences of Environmental Crisis (CoL) is the first practice-led research project to use sound and listening as a framework for expanding understandings of Indigenous Pacific human-environmental relations in the face of rapid ecosystemic transformation. Sonic practices such as storytelling, poetry, singing, music and listening are widely used in Pacific cultures to connect to, make sense of, and communicate knowledge about, the world. Drawing on these practices, this project innovates an interdisciplinary ""sonic geography"" to help scholars and advocates better conceive of the holistic, multifarious and hyperlocalised ways that environmental crisis is felt and attended to. In doing so, it expands existing literature beyond narratives of ""vulnerability"" and ""resilience"", and problematises the politics of representation and translation of Indigenous Pacific experiences into Western ideas and knowledges. CoL deploys ethnographic material from five frontline Pacific Island sites as a foundation for understanding and communicating Pacific Indigenous-environmental relations through written and artistic forms, including a research monograph, workshops, original sound art pieces and a research exhibition. Based at the world leading Centre for the GeoHumanities (RHUL) in the Department of Geography, the Fellow will be supported in a rich research environment. The Fellow's time at the CGH will not only enhance their trajectory as a research leader in their discipline of Geography, but will also advance their transferable research skills and build their Geography teaching profile. Through a comprehensive suite of research, dissemination and career training activities, this MSCA will greatly increase the Fellow's capacity to secure
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Integrated software platform for Green ENgineering dESIgn and product sustainability' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

The project (36 months long) aims at developing a software engineering platform, called G.EN.ESI for eco-design and product sustainability of electronic and mechatronic products. G.EN.ESI is realized through a set of new tools that support designers’ choices from an environmental point of view. These tools allow to evaluate technical solutions in the early design phases and their impact on the whole product life cycle.The platform is the physical implementation of a eco-design methodology that aims at three objectives: speed, diffusion, and usability. Firstly it allows a rapid environmental assessment of design choices since the early stages of conception and design. Secondly, it promotes both the diffusion of the principles and instruments of the eco-design and their usability in technical design departments. That is possible  through the simplification of analysis technologies and their integration with traditional tools used in the process of product development.The industrial field of reference, where the methodology and the tools are tested, regards small and large appliances. In terms of environmental impact all the phases of product life cycle (from production to disposal) are important and the parameters to be controlled at design time are several. Materials, processes, assembly methods, packaging, transport systems, geographical location of use and disassembly methods are just some of the elements that should be considered.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'The Shop-Lab-Network for Test and Design of Hybrid Shop Environments based on multi-modal Interface Technology' (SHOP-LAB).

assistant: **Innovation**

The objective of the SHOP-LAB proposal is the test and design of multimodal interfaces in hybrid shop environments. The business of traditional inner city shops will be augmented with digital technologies and services. In order to integrate users (shop owners and customers) into the development of prototypes public test beds in a model shop and in real shops will be established. Cultural differences in the use of new technologies and in business habits in general can be studied and the design process sensitized to these cultural aspects. The modular "tangram approach" allows a maximum of flexibility.OBJECTIVESThe objective of the SHOP-LAB project is the development of hybrid shop environments based on multimodal interfaces (and interspaces) which combine the virtues of real world shops with the additional value of digital technologies and services. The alienation of many people to new technologies will be reduced by integrating their needs and experiences in the design process. Therefore public accessable test beds will be installed in a model shop and in real shops so that an active participation of users is guaranteed and both social and practical user acceptance can be tested in realistic environments. The enormous cultural value of traditional retail shops in different European regions as well as the different European mentalities will regarded in the participatory design of the hybrid shop modules.DESCRIPTION OF WORKThe SHOP-LAB project consists of the following elements: hardware interface design, software interface design, shop construction and design, multimedia application design, usability and user acceptance test design and inter-cultural communication design for the development of hybrid shop environments. These environments consist of "Shop-Lab modules" suc