RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Integrated self-assembled SWITCHable systems and materials: towards responsive organic electronics – a multi-site innovative training action' in the context of a Horizon 2020 call.

assistant: **Objectives**

iSwitch will offer top-level multi-disciplinary and supra-sectorial training to a pool of talented young researchers, involving contributions from different scientific and technological fields such as, supramolecular chemistry, materials, nanoscience, physics and engineering. iSwitch’s appointees will be trained through lecture courses, dedicated international schools and workshops, topical conferences, secondments to other consortium nodes and an ambitious and carefully planned research activities benefiting from the expertise of world-leading senior PIs and of younger but well-established PIs with outstanding track records in training and research. Additionally, iSwitch will generate new ground-breaking S&T knowledge needed to obtain efficient and fast switching in supramolecular electro- and opto-active materials as a response to external stimuli. This will be accomplished via controlled self-assembly of multicomponent architectures incorporating molecular switches, for fabricating responsive and multifunctional optoelectronic supramolecular devices. We are particularly interested in developing nano- and macro-scale switchable transistors and light-emitting devices as new solutions to (nanoscale) multifunctional organic-based logics.The specific training and research objectives are:- Design and synthesis of a (macro)molecular toolbox including electroactive and responsive systems as well as semiconducting and metallic nanostructures- Controlled interfaces of switches on (non)planar surfaces- Self-assembly of multicomponent systems into multifunctional architectures and materials- Multiscale structural, optical and electrical characterization of systems including Scanning Probe studies and time-resolved spectroscopy- Fabrication and characterization of switchable devi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Metabolic Drivers of Epigenetic Modifications: metabolic inducers of histone post-translational modifications in a biological setting' (M-DrivE).

assistant: **Innovation**

Post-translational chemical modifications to histone proteins – the storage units of DNA – influence gene expression electrostatically and through specific protein-protein interactions, the study of which is known as epigenetics. Although many enzymes have been identified which add, remove or recognise these modifications, the implication of metabolism in the induction of epigenetic states is a recent development – particularly highlighting acetyl coenzyme A (CoA) as the sole donor for acetylation. Due to the lack of appropriate biochemical tools, this emerging field has not yet been exploited, however Acies Bio’s leading work on the efficient synthesis of 4’ phosphopantetheine (4-PPT), a natural precursor of the prolific substrate CoA, places us in a unique position to realise the novel approach of metabolically inducing epigenetic modifications. In progress towards therapeutic use bypassing faulty metabolism in a rare genetic disorder, we have shown that 4-PPT is cell permeable, serum-stable, tolerated at high doses without side-effects, and can also upregulate histone acetylation. This presents a previously unexplored route to develop 4-PPT as a novel vehicle for the delivery of diverse intracellular acyl-CoA species, and subsequent histone modification. Taking advantage of the interplay between metabolic and epigenetic states, and the complementarity of backgrounds that Acies Bio and Dr Sekirnik can provide through an international partnership combining expertise in both fields, our proposed work would illuminate recently characterised histone acylations. By synthesising novel 4-PPT derivatives, and demonstrating their activity on a cellular and model organism level, we will develop new tools to enable rapid enrichment of rare endogenous modifications to probe their
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'INFORMATION TRANSFER WITH CORRELATED NOISE AND MEMORY EFFECTS IN QUANTUM COMMUNICATION TECHNOLOGIES' in the context of a Seventh Framework call.

assistant: **Objectives**

Nowadays, Information and Communication Technologies (ICT) play increasing central role in the socio-economic, scientific and technological development of our information society. Recently, the peculiar features exhibited by matter at the microscopic (quantum) level, reached by continuous miniaturization, have delivered very interesting advances in many ICT areas, i.e. quantum information science. At this level noise plays an important role, although so far scientists have mainly investigate the impact of uncorrelated noise on quantum ICT (QICT), i.e. noise sources not exhibiting correlations in space and in time. However, investigating the latter will become increasingly pressing with the continuing miniaturization of information processing devices and with higher and higher transmission rates over quantum channels. Here, we will investigate and characterize in a universal framework correlated noise and memory effects in QICTs, which will have a significant impact to realistic optical and solid-state implementations. Particularly, we will deepen a new many-body approach to memory channels (Plenio and Virmani, 2007) and generalize it to bosonic channels, e.g. optical fibers used in long-distance secure quantum communication. Finally, we will propose experimental tests of the expected results, opening up new horizons for realistic QICTs, i.e. fast communications and nanotech processors. This highly original and innovative proposal has the advantage of uniting quantum information theory and condensed matter physics, two very fruitful branches of physics, in which European scientists both on the theoretical as well as on the experimental side are renowned worldwide with Imperial College being a centre of excellence. Under the tutoring of a leading expert in the field (Prof
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'TERAhertz integrated systems enabling 6G Terabit-per-second ultra-massive MIMO wireless networks' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

TERA6G aims at developing disruptive photonic wireless transceivers enabling Terabit-per-second data throughput capacity and massive Multiple-Input/Multiple-Output multi-antenna techniques operating in the millimeter-wave (30 GHz to 300 GHz) and Terahertz (300 GHz to 3 THz) bands of the spectrum, unlocking the “Fiber-over-the-Air” concept. The concept uses  independently steerable wireless pencil-beams with fiber data throughput capacity, allowing mobile site connectivity scenarios in dense urban areas with macro/street level densification, temporal mobile site connectivity in ad-hoc networks, and connectivity to moving objects in public or private networks.Hybrid photonic integration is the key enabler technology to develop a Blass-Matrix Transmitter and an incoherent-multi-band Receiver with key disruptive characteristics, including agility (handling any modulation scheme and continuous tuning of the carrier frequency across the target spectrum range), scalability (handling large number of beams with 2-dimensional antenna arrays for beamformed antenna gain >25 dBi and > 100º steering angles beam-steering) and reconfigurability (performing a variety of functions, from wireless data transmission, or radar ranging to channel sounding).These disruptive wireless transceiver modules characteristics will be exploited at network level by developing the dynamic allocation of the network resources that these bring. We plan to dynamically analyze the position of the different wireless nodes and the channel resources using respectively the radar ranging and channel sounding techniques enabled by the novel reconfigurable TERA6G photonic transceivers. This will allow for novel scheduling methods capable of alternating paths to establish the connectivity, ensuring connection reliabi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Bio-conjugatable and Bio-responsive Near Infrared Fluorochromes'.

assistant: **Innovation**

Near-infrared (NIR) fluorescence molecular imaging is a supra-discipline that enables visualisation of cellular function and real-time tracking of molecular processes in living organisms without perturbing them.  If exploited to its maximum potential, NIR-fluorescence could have hugely positive impact for early stage diagnosis of diseases such as cancer, neurological and cardiovascular disease, the optimisation of preclinical and clinical tests for new medication and act as a real-time guide during surgery. This proposal seeks support for a MSC Fellowship to develop new biologically responsive off to on switchable NIR fluorochromes i.e. NIR fluorescent probes that respond selectively to cellular uptake and with specificity for cancer cells achieved through bio-conjugation with proven targeting agents.  Specifically, the focus is on the design, synthesis, photophysical characterisation, in vitro cell imaging and preliminary in vivo assessment of such probes for the ultimate in vivo detection of colorectal cancer metastasis.  Colorectal cancer is the third most common cancer and remains a major public health issue in Europe because of its high prevalence, morbidity, and mortality.  The synergetic combination of the host laboratory’s interdisciplinary expertise, the host institution’s ability to deliver a comprehensive training program and the applicant’s excellent prior Ph.D. training experience in developing fluorescence chromophores with function-tailored photophysical properties is the perfect match to deliver the project goals and provide the stepping stone to independent researcher for the applicant.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Regenerative treatment of complete Traumatic Spinal Cord injury with a surgical implantation of a biodegradable device with FGF1 and nerve grafts' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Today there is no regenerative therapy available for treatment of complete spinal cord injuries (SCI). BioArctic Neuroscience develops a novel treatment of complete SCI. The method is based on the regeneration of functional nerves in the injured spinal cord. Nerve grafts are transplanted into the injured spinal cord, by using a biodegradable device, loaded with a growth factor and nerve grafts (these three components are abbreviated SC0806). Efficacy and safety of the treatment has been demonstrated in an in vivo model of SCI. The therapy has been designated Orphan Drug status in Europe and in USA. Ethical approval to commence into clinical trial in Sweden was recently granted.The proposed project is the first clinical trial of the treatment of complete spinal cord injury. Following surgery at the Karolinska University Hospital, patients will receive rehabilitation in their home countries, with state of the art robotics equipment, at clinics in Denmark, Finland and Sweden. This clinical study will be the first in-human trial with this new treatment concept. Several interim analyses are included in the study design to secure the safety of the patients. This is a single dose study in up to 3 sequences (A, B and C) in 27 subjects with complete traumatic SCI. In the first sequence (A), 6 subjects will be randomized to a surgical procedure where SC0806 will be implanted at the spinal cord, and receive robotics assisted walking training for 18 months, and 3 subjects will be randomized to specific walking training only. For safety reasons, the first three subjects will be operated on and implanted with at least 1 month in between. If efficacy is demonstrated,  control subjects from (A) and (B) and (C) will later be given the opportunity to receive treatment with SC0806.The pro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Photonic Vector Network Analyzers' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

The deployment of 5G networks and the upcoming deployment of 6G in the next decade is essential to advance wireless communication for keeping pace with modern data hunger. 6G will incorporate first channels in the Terahertz domain (100 GHz -10 THz), however, terahertz technology in communication applications has a main bottle neck: the lack of powerful sources and versatile components. In order to engineer these towards maturity, sophisticated characterization tools are required to identify design flaws. The most prominent of these are Vector Network analyzers (VNAs) a class of systems currently dominated by electronics. Meanwhile, photonic technologies start to become competitive with established electronic technologies in the lower THz band and already excel beyond 1 THz in terms of dynamic range. Optical comb technologies enable frequency accuracy and stability beyond that of electronic systems, potentially at a fraction of the cost. This project aims for the development of two photonic prototype systems: (i) a photonic frequency extender for the WR10 band, compatible with electronic base band VNAs and (ii) a completely photonic VNA based on a frequency comb with a bandwidth of several THz, spectral purity better than that of electronic VNAs and seamless tunability over the whole range. The technology to be developed in this project will simplify characterizing devices over a larger frequency range at (much) lower cost, enabling large scale deployment of VNA systems. This will, in turn, foster development of Terahertz systems for further key applications besides communication, e.g. in spectroscopy, including medical applications, industrial-scale non-destructive testing and quality control as well as security.


**Keywords:** Vector network analyzer, photonic system,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Improving chemical penetration during leather manufacture', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

Penetration of process chemicals into and through the structure of hides and skins is a major factor influencing all stages of leather processing. To make good quality leather these chemicals need to penetrate through the substance of the skin and into the hierarchy of the structure consistently and evenly and for economic viability this needs to be achieved as fast as possible. The proposed project aims to examine the factors affecting penetration and the information gained will be used to optimise processes. Methods developed to optimise penetration will result in an improvement in leather quality, and savings through a more efficient usage of chemicals and reduced energy usage. Reduced processing times will also facilitates a more rapid response to customer orders.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Electricity market liberalisation in europe (emelie); market imperfections and its implications on the european economic and environmental situation.' under Fifth Framework.

assistant: **Concept**

Objectives and Problems to be solved:Main scientific goal of this project EMELIE is the assessment of the economic and environmental long-term impacts by the liberalisation of the European electricity market. For that, a unified, sophisticated European game theoretic modelling tool as decision support tool is developed. Market power is one important reason of market imperfections or distortions. Main aim of this modelling tool is to investigate the different strategic behaviour opportunities of European electricity suppliers. Primarily, EMELIE focuses on the investigation of the liberalisation of the European electricity market and its potential impacts on market developments and thus impacts on available technologies, environmental developments and the economic competitiveness in the individual European countries and in Europe as a whole. Description of Work: The EMELIE project aim is to develop a modelling tool that can serve as a decision support tool as well as a tool for analysis of various strategic behaviours of the European electricity market. The value added of this modelling exercise is that it is a dynamic game theoretic model that aims to provide useful insights on various aspects concerning the functioning of liberalised electricity markets in the context of a transition process from a monopolistic market to a perfectly competitive market. The project aims that the model will incorporate some of the constraints determined by the current developments in European electricity market such as:environmental protection,increased share of renewable energy sources in the national energy mix and bilateral electricity trading as well as emissions trading. These constraints (and as a consequence the market response to them) are of crucial importance both to decision ma
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Disruptive Technology for the Global Laundry Equipment Market' to be submitted under Horizon 2020.

assistant: **Abstract**

LIRON 2020 addresses the €Multi-Billion global market for domestic laundry equipment with a highly innovative, disruptive technology that will revolutionise the industry and provide significant economic, lifestyle and environmental benefits.There are an estimated 840 million domestic washing machines in use worldwide, with predictions of 36% growth by 2020 and 62% by 2030.  Together, these washing machines account for approximately 2% of the total residential sector electricity consumption and utilise about 19 billion cubic metres of water per year.With energy and water prices soaring there is a constant drive towards more energy- and water-efficient laundry technology within the home.  In addition, there is a further demand from consumers to make their lives easier and improve the time-efficiency of their laundry process.  Woodrow Scientific Limited (WSL) was established to address this need, inventing methods and apparatus that enable “on demand” cleaning of garments with massively reduced electricity and water consumption and without the fabric wear and tear of conventional washing machines. The technical feasibility of WSL’s LIRON™ technology has been proven with the world’s first laser-laundered shirts and informal consumer research has identified a market appetite for the unique technology and lifestyle benefits it offers.   The LIRON-2020 project presents an opportunity for WSL to further evaluate the market feasibility and identify the optimum route to commercialising the technology for this >€1Billion global market.  Horizon 2020 funding will enable the company to further validate the performance benefits of its unique technology, strengthen and expand its IP portfolio and prepare the business strategy to leverage further investment / partnership and (potential