RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Physiological bases of prosocial behaviors' (PHYSPROSOC).

assistant: **Innovation**

Social life is a mix of cooperation and competition. A critical component of cooperation is proactive prosociality, arguably contributing to the emergence of complex cognition. Recent findings in corvids reported similarities in the behavioral and cognitive levels between birds and mammals, suggesting convergent evolution of socio-cognitive skills. This project aims to understand the development of prosocial behaviors and their underlying physiological mechanisms in two avian species – Carrion Crows and Ring Doves. The main premise of this project is that the brain governs both behavior and autonomic body responses, thus, autonomic biomarkers can be used to gauge brain activity during complex behaviors such as social interactions. A newly established methodology will be deployed to continuously monitor autonomic biomarkers such as heart rate and body temperature in two or more interacting partners during forming alliances and cooperative, affiliative, and sexual behaviors. The biomarkers will be used for longitudinal measurements of proactive-reactive social behaviors during the socio-cognitive development of crows to predict prosocial behaviors and individual differences in social integration. Altogether, this research will contribute to the understanding of physiological mechanisms driving social behavior and bridge the gap between studies in animal cognition using a purely behavioral approach and invasive neuroscience methods to study brain circuits underlying behavior.


**Keywords:** Animal physiology,  Neuroethology, Socio-cognitive development, Cognitive biology
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Regulating the Environmental Impacts of Artificial Intelligence in the Public Sector' (SUSTAIN-IA-PUB) targeting Horizon Europe.

assistant: **Abstract**

The project “Regulating the Environmental Impacts of Artificial Intelligence in the Public Sector” (SUSTAIN-IA-PUB) addresses the urgent need to govern the environmental costs of AI, which remain largely invisible and unregulated despite AI’s role as a driver of the digital and green transitions. Current EU legislation, including the AI Act (Reg. EU 2024/1689), pays only marginal attention to sustainability, leaving a regulatory gap that this research seeks to fill. The main objective is to promote environmentally responsible AI adoption in the public sector through the development of methodologies and regulatory strategies that are adaptable, transparent and operational. The project pursues four goals. First, it will map and compare how public administrations in Europe and beyond currently assess the ecological footprint of AI, identifying gaps and best practices. Second, it will design an interdisciplinary methodology, grounded in lifecycle analysis and enriched by legal and technical expertise, to measure both direct impacts such as energy and water use and indirect effects such as rebound phenomena. Third, it will translate these findings into actionable regulatory instruments, including procurement criteria, reporting obligations and soft law tools that public bodies can realistically adopt. Finally, it will engage society through a citizen guide, a policy brief and an open-access repository to raise awareness and empower informed debate. By integrating law, environmental studies, computer science and governance, SUSTAIN-IA-PUB contributes directly to Horizon Europe’s priorities on the twin transitions. It will strengthen the capacity of Member States and public institutions to adopt AI systems that are lawful, effective and ecologically sustainable, positioning en
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Photocatalyzed enantiodivergent synthesis of homoallylic and carboxylic acids featuring heterodiaryl quaternary carbon stereocenters' (PEACE), addressing dissemination and exploitation.

assistant: **Impact**

The synthesis of heterodiaryl-based quaternary stereocenters is a very challenging task in organic synthesis, especially in the creation of highly functional scaffolds. Tetrahedral, congested carbons centers bearing two different aryl moieties have great importance for structure−activity relationship (SAR) studies in pharmaceutical discovery programs. Their presence in biological active natural products makes them fundamental for the future development of new bioactive molecules. Up to now, their synthesis requires unsustainable methodologies that involve high cost, unfavourable step-economy and a negative waste profile features and need highly reactive compounds that only permit low functional groups tolerance. Moreover, the enantioselective synthesis of both product enantiomer requires the use of both catalyst enantiomers raising the cost of the process. Therefore, it is fundamental to develop a simple, scalable and environmentally friendly approach for the enantioselective synthesis of compounds comprising heterodiaryl-quaternary stereocenters and functionalized derivatives. The PEACE project aims to develop a novel photocatalyzed, enantiodivergent synthesis process leading to such heterodiarylated all-carbon stereocenters. The designed dual catalytic cycle of the PEACE project merges Pd and photoredox catalysis to promote the enantioselective construction of new sp3-sp2 carbon-carbon bonds resulting into products featuring a quaternary carbon stereocenter. The enantiodivergent strategy is based on a judicious choice of structurally modular reaction partners with switchable aryl groups. The combination of VCCs (vinyl,aryl-substituted cyclic carbonates) and a new aryl radical precursor offers an innovative enantiodivergent reaction pathway leading to challenging quate
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Alternative Fuels and Biofuels for Aircraft Development'.

assistant: **Objectives**

ALFA-BIRD aims at developing the use of alternative fuels in aeronautics. In a context where the price of oil is increasing and with impact of fossil fuels on climate change, the sustainable growth of the civil aviation is conditioned by the respect of the environment. In this context, using biofuels and alternative fuels in aeronautics is a great challenge, since the operational constraints (e.g. flight in very cold conditions) are very strict, and due to the long lifetime of current civil aircraft (almost 50 years). To address this challenge, ALFA-BIRD gathers a multi-disciplinary consortium with key industrial partners from aeronautics (engine manufacturers, aircraft manufacturers) and fuel industry, and research organisation covering a large spectrum of expertise in the fields of aeronautics, biochemistry, combustion as well as industrial safety. Bringing together their knowledge, the consortium will develop the whole chain for clean alternative fuels for aviation. The most promising solutions will be examined during the project, from classical ones (plant oils, synthetic fuels) to the most innovative, such as new organic molecules. Based on a first selection of the most relevant alternative fuels, a detailed analysis of up to 5 new fuels will be performed with tests in realistic conditions. Then, at the end of the project, the review of the performance of these new alternative fuels will be made regarding the economical, environmental and technical efficiency. Based on this result the most relevant strategy for future alternative fuels for aircraft will be defined, as well as an implementation plan and industrial applications. The impact of such a project will be of first importance for the evolution of aviation within the next 5 decades. Developing alternative fue
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Resolving Ocean Macroscale Turbulence' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

"Resolving Ocean Macroscale Turbulence"" (ROTurb) is a proposal to fund a fellowship to be carried out by the Experienced Researcher (ER) Simone Silvestri at the host institution Polytechnic University of Turin, Italy (POLITO) in the Department of Environment, Land and Infrastructure Engineering (DIATI) under the supervision of main host Professor Jost von Hardenberg. The aim of the proposed work is twofold. From a scientific perspective, the goal is to investigate the role of macroscale turbulent processes in ocean models through a hierarchy of coupled ocean sea ice simulations that follow the ocean model intercomparison project OMIP2. Regarding technological innovation, the aim is to develop a submesoscale permitting model that runs at climate-relevant scales. Macroscale turbulence in the ocean, broadly subdivided into mesoscale and submesoscale features, is the primary driver of the lateral transport of heat, carbon, and nutrients.Furthermore, submesoscales, associated with surface fronts, have been suggested to play a pivotal role in determining the vertical transport of heat and carbon in the ocean and modulating air-sea fluxes. However, due to their small scale, these processes are typically not represented in global ocean models. The ER and colleagues have recently developed a model that, by leveraging Graphical Processing Units (GPUs), achieves computational performance up to 100 times higher than state-of-the-art models. This new model, called ClimaOcean, enables unprecedented high-resolution simulations, making it possible to explore kilometer-scale turbulent processes and their impact on climate-relevant metrics within a global ocean framework for the first time.""


**Keywords:** Physical Oceanography, Ocean Turbulence, High-resolution modeling
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The discovery, development and demonstration of biocatalysts for use in the industrial synthesis of chiral chemicals' (KYROBIO), addressing dissemination and exploitation.

assistant: **Impact**

The objective of KYROBIO project is to broaden the toolbox of single enantiomer chiral chemicals that are produced by industry in Europe using biotechnological routes. The main target is applications of lyase enzymes to selectively synthesize molecules with multiple chiral centres applying enzymatic carbon-carbon and carbon-nitrogen bond formation as the key technical platforms. We will then apply synthetic biology to improve fermentation processes in order to generate better enzymes.  Chiral compounds are an important class of chemicals that biocatalytic transformation has already demonstrated great potential to compete with chemocatalysts in their production with associated benefits that come from reductions in use of organic solvents, toxic metals and energy but application has been relatively limited. KYROBIO will address the main challenges with moving forward to the next generation of added value industrial applications of white biotechnology for high value chemical synthesis.Using a supradisciplinary approach ranging from enzyme development, chemistry, molecular biology, fermentation and innovative isolation techniques the bottlenecks to applying this new technology will be overcome. It is expected that promising candidate chemicals will be commercialised within three years of completion and so scale up with economic and feasibility studies that are also key technology developments.The consortium includes a strong presence of SMEs including SME leadership and also a large multinational company which ensures multiple routes to market for the outcomes of this project. We will also have economic and life cycle analysis coupled with significant dissemination plans to ensure wider understanding of this technology that will lead to increased acceptance and uptake. The
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Remediation of hearing loss' (HEARINGTREAT) under Sixth Framework.

assistant: **Objectives**

Hearing impairment is one of the most common and debilitating disorders, adversely affecting all aspects of life. The mission of Remediation of Hearing Loss HearingTreat" is to strengthen the international position of Institute Physiology and Pathology of Hearing in the field of otolaryngology and audiology and shift Institute's research and development potential towards advanced field of new therapies for hearing impairment.The main project objective is to transfer the knowledge to the Institute and improve the skills of Institute's researchers to develop advanced, multidisciplinary studies on hearing preservation after cochlear implantation and combined stimulation with implant and hearing aid (termed electric-acoustic stimulation or EAS) The host institution has performed many surgeries, pioneering the particular technique of partial deafness cochlear implantation (PDCI ), and achieved unrivalled rates of hearing preservation, building up a large group of patients utilizing EAS stimulation. The patient group is in fact the largest homogenous group to be found globally, and the host institute can provide excellent facilities to allow research to be carried out on volunteers.The areas of competence to be developed are:1) Determination of the optimum fitting parameters for implant and hearing aid when applied together, leading to maximal sound reception in noise, music appreciation, and localization ability (this will also lead to optimum usage of a new combined hearing device developed by two European companies).2) An improved understanding of ways to determine the patients' pathologies and disabilities both before and after implantation and factors determining benefit."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Towards clinical translation of new gene targeting technologies for correcting inherited mutations and empowering adoptive immunotherapy of cancer'.

assistant: **Concept**

Substantial evidence supports the therapeutic potential of ex vivo gene therapy based on Hematopoietic Stem Cell (HSC) or T lymphocytes to treat inherited diseases or cancer. Yet, the intrinsic limitations of current gene replacement approaches based on semi-randomly integrating vectors, and the occurrence in some clinical trials of severe adverse events related to gene transfer, prevent safe deployment and broad application of gene therapy. This project aims to overcome these limits by exploiting the results of an earlier highly successful integrated project (PERSIST), which demonstrated the potential of gene targeting technologies based on engineered nucleases to provide radical new solutions to these hurdles. By homology-driven repair of a nuclease-targeted dysfunctional gene, we will insert a functional copy downstream its own endogenous promoter in HSC, thus restoring both function and physiological expression control. For adoptive T-cell therapy, we will combine nuclease-mediated disruption of the endogenous TCR genes with transfer of tumor-specific TCR, thus editing T-cell specificity at the genetic level. We will develop these innovative approaches into robust, scalable and clinically ready processes for safe ex vivo genetic modification of hematopoietic cells, and apply them to the treatment of paradigmatic diseases that provide a favourable risk-benefit ratio for clinical testing. Because both HSC and T-cell based gene therapy strategies share methodological aspects and technological challenges, we will address them systematically by involving a SME which holds unique know-how and top-level expertise in vector manufacturing and HSC and T-cell processing, as already established for our previous and ongoing gene therapy trials. Our findings will lead to the desi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'dataFlow: A Data-driven Fluid Flow Solving Platform' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

With the recent breakthrough of deep learning methods, we currenty see the advent of employing this methodology in the context of physical simulations. Such simulations are widely used in numerous industrial fields, starting from car and airplane manufacturers, over computer graphics and animations to medical blood flow simulations.  The market for computer simulations is currently exceeding 15 billion USD world wide, with rising trends, and 3 billion spent in Europe alone.  A significant fraction of these simulations focuses purely on solving various forms of the Navier-Stokes equations. While right now virtually all of these simulations use traditional solvers, we estimate than only a few years from now there will be a significant fraction of deep learning powered solvers.Thus, we are at the right point in time to lay the foundations for commercializing the technology of deep learning for fluid simulations.  The goal of this PoC project is to develop a first commercial flow solver based on deep learning that can predict fluid flow solutions almost instantly using a pre-trained model.  This project will enable the team of Prof. Thuerey to mature the algorithms developed as part of the ERC Starting Grant \realflow, and turn them into the basis of a marketable product. The initial models will be thoroughly tested and validated, in order to satisfy industrial requirements for reliability and accuracy.  In addition, this PoC aims for establishing a platform for flow data collection, interface standards, and trained models.  This platform will be developed in conjunction to the deep-learning powered flow solving application, and provide research connections and publicity in parallel to it.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Popular Government in Global Perspective: History, Principles, Institutions, and Experimentations' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Representative government is characterized by the guarantee of basic political liberties, the centrality of elections, restricted avenues for citizen participation, and the relative independence enjoyed by representatives. It has become the dominant alternative to authoritarian government worldwide, to a point where it has eclipsed the diversity of ways to organize collective self-government. This is regrettable because representative government 1) relies on elitist premises that are increasingly being challenged; 2) obscures the diversity of forms that democratic representation can take and its compatibility with extensive citizen participation; and 3) suffers from unequal responsiveness to the political preferences of citizens contributing to social and political inequality. Considering this, POPGOV aims to expand our collective democratic imaginary by uncovering alternative ways of realizing the democratic ideals of autonomy and equality that empower ordinary citizens and not only elites (what we call “popular government”). Currently, theoretical discussions of alternative democratic models remain too often disconnected from empirical research, and empirical research from history. We seek to remedy this by combining in an unconventional and mutually supporting way historical, comparative and theoretical approaches to uncover the basic principles and institutions uniting and differentiating conceptions and practices of popular government across the world. We also seek to identify the main challenges that are likely to be faced in the realization of these principles and to learn from previous failures of their implementation. To compensate for the Western-centric bias of dominant research in these fields, we embrace a truly global approach. Doing so, we aim to break ne