RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Cosyma'.

assistant: **Objectives**

In the past few years, complex systems and materials has become a major interdisciplinary scientific field involving physics, biology, chemistry, mathematics, medicine and social sciences like economy. The role of statistical physics in this new field of science and technology has been accelerating; in particular many different phenomena and processes (considered in the past as belonging to separate research fields) have now a common description.Methods developed for studying order phenomena in simple systems have been generalized to more complex forms of matter (polymers, biological macromolecules, glasses, etc.) and complex processes (e.g., chaos, turbulence, economy, jamming, biological functionalities). Pillars of such a description are scaling and universality. The aims of the proposed School are to provide an actual overview of the field and a more detailed examination of those topics within the field that are currently of interest in science and technology.The main objective of the School are: to educate the students in the concepts and specifics of this new interdisciplinary field of complex systems, to promote the formation and qualification of young researchers and their international collaborations, and foster the development of the actual knowledge in science and technology.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Dyadic Secures The Breach' (DSTB) under Horizon 2020.

assistant: **Objectives**

Over the last years, the world has seen an unprecedented escalation in the number and size of data breaches. In 2013, a total of 550 million identities were breached; a 62% increase over 2012. In addition, the cost of breaches is rising, with a worldwide average of over $3 million per breach. Hacking is the primary causes of data breaches, and today’s existing solutions are simply not sufficient to meet the threat.The objective of Dyadic Security is to provide high security to organizations, and to protect digital assets, even in the event of a network breach. Dyadic’s Distributed Security Module (DSM) is a unique software-only offering that provides the highest level of security while being affordable and easy to deploy. At the core of the DSM lies cutting-edge technology based on decades of cryptographic research on secure multiparty computation (MPC). Dyadic’s DSM solves the inherent single point of failure in all of today’s security systems. Strong cryptographic solutions exist for protecting data, securing web traffic, authenticating users, and so on. However, they all rely on the secret key and authentication credentials (e.g., passwords) remaining secret. In today’s reality where hackers get past firewalls and penetrate deep into networks, these keys and credentials are stolen thereby rendering all cryptographic protection useless. Dyadic’s DSM randomly splits keys and credentials across servers so that they are never in any single place to be stolen. The advanced protocols used in the DSM ensure that even if some of the servers are breached and completely controlled by an attacker, the secrets and credentials cannot be stolen. The result is that digital assets remain safe, even when all else has failed and attackers are inside the network. Dyadic has a disruptiv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Hybrid endoscope for esophageal in vivo histology and histochemistry' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

ESOHISTO proposes a radically new scientific concept to revolutionize disease research, diagnosis and treatment by real-time imaging of 3D organization of diseased cells, cell-cell and cell-matrix interactions, and their biochemical events in large living human tissue/organs. This transformative vision of 'in vivo histology and histochemistry' is not yet feasible for most human organs. However, GI mucosa, the shallow lining of GI tract where many GI cancer originates, is a unique tissue to implement the ambitious vision of ESOHISTO by developing disruptive endosocpic technologies to provide a long-awaited solution to the insufficient diagnosis and early detection of GI cancers. The landscape changing ability of ESOHISTO is attributed to its key invention of a volumetric-projection confocal laser endomicroscopy (VP-CLE) and a multimodal approach to complement VP-CLE with advanced imaging methods including optical coherence tomography (OCT) and optoacoustic mesoscopy (OPAM). The novel volumetric projection method allows VP-CLE to provide 3D cellular features and molecular profiles at high speed and without any mechanic parts in the distal endoscope. OCT and OPAM delivers 3D morphology and pathophysiology of GI mucosa with an imaging depth far exceeding microscopy. The combination of VP-CLE, OCT and OPAM in a miniaturized endoscope heralds a paradigm-shifting GI cancer diagnosis scheme by replacing insensitive white light endoscopy and biopsy with comprehensive 3D OCT/OPAM inspection to identify subtle lesions and following 'zoom-in' cellular/molecular vision through VP-CLE to complete in vivo diagnosis. With its prospect of unprecedented 'in vivo histology and histochemistry' for GI cancer diagnosis and early detection, ESOHISTO is able to leverage European investment and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Biometric identification technology ethics promoting research and public debate on bioethical implications of emerging biometric identification technologies' (BITE).

assistant: **Innovation**

The BITE Project is a specific support action that aims to stimulate research and to promote international dialogue on bioethical implications of emerging biometric identification technologies. Biometrics is the application of technologies that make use of a measurable, physical characteristic or personal behavioural trait to recognise the identity, or verify the claimed identity, of a previously registered individual. Biometrics evoke several social, legal and ethical concerns.Concerns are based on a variety of factors, including fears about the centralization of biometric identification information and the potential for misuse of these data. The evolution of information technology is likely to result in intimate interdependence between human bodies and technology, the so-called informatization of the body. Bioethical implications of emerging biometrics are crucial to determine the future acceptance/refusal of this technology.The BITE Project aims to prompt research and to launch a public debate on these issues. Considering the recent EU-US controversy on air passenger records and biometric passports - and in order to compare different perspectives - the project will pay special attention to involve also non - European actors.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Particle distribution dynamics in nonlinear bifurcating networks' (BiNet), addressing dissemination and exploitation.

assistant: **Impact**

Bifurcating networks are ubiquitous in nature such as vasculature/pulmonary networks, kidney urinary tract, and branching in plants. In addition to their role of transporting the carrying fluid, these networks distribute discrete particles suspended in the fluid leading to intricate spatiotemporal particle flow dynamics. The heterogenous distribution of red blood cells (RBC) in microcirculation is an example of this behaviour, consequences of which are not well-understood. Our objective is to explain the fundamental principles and implications of nonuniform particle distributions in bifurcating networks using RBC flow in vasculature as a model system. Currently there is no systematic approach to study such complex particle distribution dynamics. We propose using droplet microfluidic as an analogue of the biological network. Microfluidics provide superb control of the droplets/particles, carrying fluid and network properties in highly engineered microfabricated devices. We aim to understand RBC distribution patterns in capillary network and the consequences during vascularization and organogenesis. Our approach is (i) to observe the in vivo RBC fractionation in chick embryo vasculature, (ii) to develop its in vitro analogue using droplet microfluidics, (iii) to develop in silico model and determine the governing parameters. This project will discover the foundations of particle transport phenomena in nonlinear bifurcating networks and address the long-lasting question of RBC nonuniformity in microcirculation and its implications as a groundbreaking contribution. Another key outcome will be correlating RBC heterogeneity to corresponding organ growth by visualising two bifurcating networks simultaneously: vasculature and urinary tree, using kidney organoid xenotransplantat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Clean and Reliable forming Of Stainless Steel'.

assistant: **Innovation**

Sheet metal working is an essential technology for manufacturing goods in Europe. A specific part of this sector, targeted in this proposal, comprises ca. 500 SME's with a press shop and employs an estimated sixty five thousand people in the European Union. This sector experiences strong competition from low labour cost countries and a significant portion of these jobs are lost to non-EU countries each year. The only sustainable way to end this is permanent innovation, not only by developing new products but equally important: by adapting new production technologies.This proposal addresses both. Reliability and cleanliness play an important role in sheet metal forming of stainless steel. The lack of these results in scrap and hazards for the environment and worker's condition. Because stainless steel is a relative costly sheet material (ten times more expensive than low carbon steel), a drop in production yield, for e.g. due to climate influences or variations in material batch properties, is a serious problem. At present, an improvement of reliability can only be realised at the cost of cleanliness and vice versa.The technical limitations of the present state-of-the art and key barriers to growth of clean and reliable forming of stainless steel are:1 .Clean processes lack forming reliability, since galling occurs after a few operations; and2. Reliable processes involve chlorinated paraffin and solvents based on HFCs and involve controlled temperature forming, which are respectively non- sustainable or hardly assessable for SMEs.The objective of the proposed research is to develop innovative solutions comprising of easy-to-clean ECO lubrication, optimised anti-galling tool surfaces and forming with active temperature control, that will increase the lifetime of the formi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Evolvability and drivers of photosynthetic transitions in flowering plants' to be submitted under Seventh Framework.

assistant: **Abstract**

Several carbon concentrating mechanisms (CCM) have evolved to counteract the deficiencies of the classical photosynthetic pathway (C3 photosynthesis). Their multiple origins represent one of the most striking examples of convergent evolution and make them especially suitable for comparative evolutionary studies. In land plants, the two main CCM are CAM and C4 photosynthesis, which confer an advantage in arid and warm environments. These CCM are ecologically and economically very important, but their evolutionary history remains poorly understood. In particular, the number of transitions between the different photosynthetic types and their directions are still unknown. In this project, a multi-scale phylogenetic approach will be used to address the evolvability and reversibility of the different photosynthetic types together with the factors that influence the probability of a given plant group evolving one or the other CCM. Using two plant groups with a high variability in the photosynthetic types (Poaceae and core Caryophyllales), the genetic changes on an enyzme involved in both CAM and C4 pathways will be identified and, in combination with species phylogenies, will serve to retrace past photosynthetic transitions. The effect of different plant characteristics on CCM evolvability will be tested through comparative analyses in the generated phylogenetic framework. This approach will finally be transferred to a grass genus extremely variable in its photosynthetic characteristics, to shed light on CCM microevolutionary processes. Overall, this project will bring important insights about the causes and consequences of one of the greatest ecological and evolutionary successes in plant history.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Connected Transitions: Social Democratic Party Networks and the Crisis of the Keynesian Compromise in Europe' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The 1970s are widely considered in historiography as a turning point in European and international history. Amid major social and cultural shifts, the decade witnessed the crisis of the post-World War II patterns of ‘embedded liberalism’, economic growth and state interventionism, and set the stage for the emergence of a new globalisation process that would redefine the concept of national sovereignty.This project investigates these processes from the point of view of the European social democratic movement. A leading political force in many European countries for most of the decade, the social democrats were especially hard hit by the emerging new conditions, which called them to revise their programmes and approaches. The research focuses on three main aspects of their response to the crisis of the postwar ‘Keynesian compromises’: A) Social democracy as a transnational political force: the exchange of ideas and the transfer of policy strategies, the learning processes and the ideological conflicts that took place within the social democratic networks. B) The European Left as a variable of the transformation of the Cold War order: the alteration of the ideological, political and economic relations between the two blocs and within each one of them, the evolution of social democracy’s transatlantic partnership, the impact of globalisation. C) Social democracy and European integration: the new debates on (and contributions to) the development of the European Community that emerged during these years in connection with the economic crisis, globalisation and the difficulties of national reformism.This analysis will be crucially supported by a broad multi-archival research, to be carried out in five European countries and in the US. As a final result, this project aims at pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Nanostructured catalyst overcoats for renewable chemical production from biomass' (CATACOAT).

assistant: **Concept**

In the CATACOAT project, we will develop layer-by-layer solution-processed catalyst overcoating methods, which will result in catalysts that have both targeted and broad impacts. We will produce highly active, stable and selective catalysts for the upgrading of lignin – the largest natural source of aromatic chemicals – into commodity chemicals, which will have an important targeted impact. The broader impact of our work will lie in the production of catalytic materials with unprecedented control over the active site architecture.There is an urgent need to provide these cheap, stable, selective, and highly active catalysts for renewable molecule production. Thanks to its availability and relatively low cost, lignocellulosic biomass is an attractive source of renewable carbon. However, unlike petroleum, biomass-derived molecules are highly oxygenated, and often produced in dilute-aqueous streams. Heterogeneous catalysts – the workhorses of the petrochemical industry – are sensitive to water and contain many metals that easily sinter and leach in liquid-phase conditions. The production of renewable chemicals from biomass, especially valuable aromatics, often requires expensive platinum group metals and suffers from low selectivity.Catalyst overcoating presents a potential solution to this problem. Recent breakthroughs using catalyst overcoating with atomic layer deposition (ALD) showed that base metal catalysts can be stabilized against sintering and leaching in liquid phase conditions. However, ALD creates dramatic drops in activity due to excessive coverage, and forms an overcoat that cannot be tuned.Our materials will feature the controlled placement of metal sites (including single atoms), several oxide sites, and even molecular imprints with sub-nanometer precision w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'In situ DNA sequencing-based microscopy for subcellular spatial transcriptomics' to be submitted under Horizon 2020.

assistant: **Abstract**

New tools are needed in spatial transcriptomics, which uses imaging to resolve the positions of RNA in their native biological contexts to reveal molecular mechanisms underlying cell states and interactions. The developing embryo exhibits complex transcriptional regulation during the maternal-to-zygotic transition, when the reservoir of maternal RNA is phased out and the zygotic genes are turned on. Existing spatial sequencing approaches cannot simultaneously achieve subcellular resolution, whole transcriptome coverage, isotropic 3D resolution, and the parallel mapping of proteins and genetic regulatory elements that is desirable to form a mechanistic picture of transcriptional regulation in any system as complex is the embryo. The nascent field of DNA microscopy is perfectly suited for the high-throughput, multiplexed, molecular mapping needs of such problems. DNA microscopy uses carefully engineered in situ PCR, next-generation sequencing, and the mathematics of stochastic geometry instead of optics to convey microscale spatial information. In 2018, I developed a 2D DNA microscopy approach based on topological reconstruction of adjacent patches of barcoded DNA “polonies”. My work is among a few papers appearing just in the last year that together constitute a new field. I will adapt my 2D topological DNA microscopy method to one based on in situ whole-transcriptome sequencing in 3D, aiming to achieve subcellular resolution. I will also develop the mathematical basis of topological reconstruction and new computational tools to deal with the 3D data. Finally, I aim to incorporate the capability to localize other molecules in parallel with the transcriptome such as oligonucleotide-conjugated antibodies targeting specific transcription factors and other genetic regulatory