RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Reprogramming of small RNA function in plant-pathogen interactions' in the context of a Horizon 2020 call.

assistant: **Objectives**

RNA silencing relies on small RNAs that act in RNA induced silencing complexes (RISCs). RISCs use base pairing to select mRNAs or invading nucleic acids such as viruses for repression. RNA silencing may facilitate gene expression changes, for example in host-pathogen interactions. Such changes require reprogramming of RISC, since a different set of RNAs must be rapidly repressed upon pathogen perception. RISC reprogramming is non-trivial: new small RNAs must be produced and be rapidly incorporated into RISC, while unwanted repression by pre-existing RISCs must be eliminated. This project focuses on understanding three central aspects of RISC reprogramming in plant-pathogen interactions. First, we will define mechanisms that allow invading RNA, but not self-RNA, to engage in positive feedback loops for small RNA synthesis, and we will investigate the specific importance of these positive feedback loops in antiviral defense. Second, we will explore how rapid proteolysis of the central RISC component ARGONAUTE1 (AGO1) governs rapid incorporation of newly synthesized small RNA. We will also explore the hypothesis that non-RNA bound AGO1 is degraded to minimize vulnerability to pathogens that use small RNAs as virulence factors to repress host immune signaling. The relevance of these mechanisms of AGO1 proteolysis in plant immunity will be investigated. These studies take advantage of our recent discovery of proteins required specifically for turnover of AGO1. Finally, we explore the hypothesis that rapid chemical modification of mRNA by N6-adenosine methylation (m6A) may bring mRNAs with poor small RNA binding sites under RISC repression. This scenario is supported by interactions between m6A reader proteins and AGO1 discovered in current work in the group. This mechanism m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Spent Fuel Characterisation' under Sixth Framework.

assistant: **Concept**

Specific Objectives 8.1.2.1. Fuel Corrosion and Radiolysis Studies Leaching experiments on alpha-doped UO2 (carbonated water, RT, anoxic/reducing conditions) with H2, O2 measurement and in presence of Fe) with H2, O2 measurement Contrasting effects of H2O2 and other ionic species on the dissolution behaviour of UO2, SIMFUEL Leaching of unirradiated MOX under reducing conditions (carbonated water, RT, co-precipitated MOX) Leaching of actinide-containing pyrochlores and/or ZrO2 and of Th-MOX 8.1.2.2. Radiation Damage and Gas Behaviour in Spent Fuels Irradiation with fission products (Xe) of transmutation (ZrN) and/or storage matrices (Nd2Zr2O7) at IRRSUD beamline, GANIL and TEM investigation on ion- irradiated Nd2Zr2O7 and ZrN Investigation of the alpha-damage annealing in MOX by thermal diffusivity measurements.Comparative study of the helium vs. fission gas kinetics in nuclear fuels by annealing in a Knudsen Cell (experimental and evaluation) Complete the characterization of Cm-doped pyrochlore He release behaviour, effusion tests on actinide-bearing IM (pyrochlores) Thermodynamic solubility of helium in UO2 and IMF's (YSZ) 8.1.2.3. Spent Fuel Corrosion Chemistry and Dynamic Leaching Testing of spent and unirradiated UO2 and MOX-fuel: electrochemical corrosion tests SUPERFACT fuel: - examination of corroded fuel rods; optical & SEM/EPMA analysis (XRD) Autoclave leaching of spent fuel under hydrogen pressure. Dynamic leaching of spent UO2 and MOX-fuel: Cutting & preparation and instant release of UO2 spent fuel 65 MWd/kgU and MOX spent fuel 44 MWd/kgU Anticipated milestones and schedule. Planned Deliverables 8.1.2.1. Fuel Corrosion and Radiolysis Studies U, Pu concentration vs. time and H2, O2 concentration vs time; redox evolution U, H2, O2, relevant fission products (S
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Anisotropic thermoelectric polymers'.

assistant: **Objectives**

Conducting polymer (CP) based thermoelectric materials (TE) gained significant interest from the scientific community due to their natural advantages such as low cost, high flexibility, lightweight and low toxicity over inorganic materials, which is beneficial for wearable or portable devices. Despite the benefits of organic TE materials, their low electrical conductivity reduces the TE performance and hinders commercialization. Chemical doping can be used to improve the electrical conductivity of CPs as it increases the charge carrier (polarons) concentration. However, the main limiting factor of electrical conductivity in organic semiconductors is their poor structural order and crystallinity. In addition, the strong coulombic attraction between the formed polarons (carriers) and the dopant counter ions hinders carrier delocalization, further limiting the TE performance. AnisoTEP will focus on developing highly conducting and crystalline polymer thin films to achieve high TE performance.   We will use methods based on epitaxial orientation and mechanical rubbing to prepare oriented and crystalline P3HT thin films. Once oriented and crystallized, thin films will be doped by unique dopants based on dodecaborane (DDB) clusters, which stabilize their electron density in their core, and the negative charge of the DDB anions stays far away from the polarons, leading to a more delocalized polaron and high conductivity. Novel doping strategies based on ion exchange will be used to introduce counter ions of different ionic radii into P3HT to investigate the impact of counterion size on the polaron delocalization and TE performance.   All the anisotropic TE parameters will be estimated, including the anisotropy in thermal conductivity and the final ZT anisotropy. This work woul
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'High Energy Rapid Modular Ensemble of Satellites, Scientific Pathfinder' (HERMES-SP), addressing dissemination and exploitation.

assistant: **Impact**

HERMES (High Energy Rapid Modular Ensemble of Satellites) Scientific Pathfinder (HERMES-SP) is a mission concept based on a constellation of nano-satellites in low Earth orbit (LEO), hosting new miniaturized detectors to probe the X-ray temporal emission of bright high-energy transients such as Gamma-Ray Bursts (GRB) and the electromagnetic counterparts of Gravitational Wave Events (GWE). HERMES-SP main goal is to design and implement the first GRBs localisation experiment through a distributed space architecture realized by a 3 +3 CubeSat federation, each equipped with the novel detector to gain a wide deep space coverage and demonstrate capabilities in precisely localising the GRB event in space. HERMES-SP exploits synergies with an ongoing project funded by the Agenzia Spaziale Italiana (ASI). GRB localisation is gained by comparing time delays among the same event detection epochs occurred on - at least - 3 detectors spaced out on different satellites. Distribution in space and event detection are the fundamental ingredient to start building up the whole scientific experiment.HERMES-SP is aiming at demonstrating detection and localisation of high-energy transients feasibility with disruptive technologies and limited effort: simple payload on nano-satellites and a disruptive level of cost-effectiveness: 1-2 order of magnitude cost lower than that standard space projects (ESA class M mission, NASA Explorer mission), 1 order of magnitude lower lifecycle  compared with 10-15 years for standard Space Science projects. The HERMES-SP represents also a step forward the HERMES Full Constellation (HERMES-FC), supposed to further increase the distributed detection points in space with several tents of detector-equipped CubeSats in LEO which timely and completely monitor the Un
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Workers, Gypsies, and the Market: The Anthropology of New Fascism in Eastern Europe'.

assistant: **Concept**

This research focuses on how market transformation gives rise to new patterns of politics that among some social groups in Eastern Europe emerge as new fascism. By focusing on two social groups that have encountered the most significant transformation in effect of the economy re-structuring after state-socialism and whose positions caused the major challenges for academics and policy makers -- heavy industry workers and Roma/Gypsies -- the project aims to offer new perspective on the anthropology of social and political movements in Europe. Building upon years-long fieldwork in Slovakia, Poland and Ukraine, the project investigates how individualism and market calculation in what I call post-peasant setting after state-socialism have paved the way for populist movement that have increasingly taken anti-Roma attitudes among social groups that have not previously shown sensitivity to ethnic conflict or neo-fascist protests. The anthropology of new fascism therefore analyses the social and political movement from the ordinary perspective of everyday eceonomic models, balancing the dominant view on macro-structural or identity-centred 'culturalist' approaches. Theoretically, the project combines the recent dialogue of anthropology and economy with literature on transformations of polities, particularly in post-socialist setting. The project intends to argue that the current rise of populism and neo-fascism in Eastern Europe can only partially be explained as being the effect of neoliberal globalization. It is argued, instead, that the perspective on the everyday distribution of power in post-peasant society and how it has been reproduced via uneven development alongside with the changes in livelihood strategies under the market proliferation into the spheres previously domi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Innovative and integrated technologies for the treatment of industrial wastewater' (INNOWATECH) targeting Sixth Framework.

assistant: **Abstract**

The main objective of the project is to investigate, assess and enhance the potentiality of promising technological options (i.e., technologies, processes and concepts) for the treatment of industrial wastewater with the specific aim to provide tailor-mad e solutions to end-users for a wide range of wastewaters. Such solutions will be essentially based on the optimised integration of the investigated options and on technological improvements with respect to treatment system components, operation and control.Referring to the investigated options and the envisaged technological solutions, the project's goals are:-Investigating and enhancing the performances of promising wastewater treatment options such as aerobic granulation, integrated advanced oxidation processes (AOP) and membrane-based hybrid processes-Achieving fundamental and technological knowledge advancements necessary for advanced wastewater treatment application in different industrial sectors -Assessing the economic and environmental sustainability of promising wastewater treatment options-Developing integrated tailor-made solutions for end-users in different industrial sectors-Transferring the developed know-how to potential end-users inside and outside the project-Favouring their actual implementation for enhancing the EU Water Industry competitiveness.In order to achieve such goals, coordinated research activities will be carried out on selected options treating different wastewater. The experiences from such activities will be merged to define tailor-made solutions for end-users in different industrial sectors. A major goal will be the definition of treatment needs and framework conditions for a wide range of wastewaters based on the specific features of the options investigate d (i.e., aerobic granulatio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Evolution of genetic network required for fruit and fruit-like structures development of land plants.'.

assistant: **Concept**

Human and animal nutritional needs are mainly based on the intake of seeds and fruits which are also sources of other priceless products useful for our own well-being. For the plants themselves, the fruits are a key to seed dispersal and ensure future plant generations. Although fruits show diverse structural and seed dispersal mechanisms across flowering plants it seems that all species might share a common  developmental network. Fruits, in the strictest sense, are only present in angiosperms and are mainly derived from the ovary wall. Nevertheless, fruit-like structures, used for seed dispersal are present also in Gymnosperms.  This research project proposes to build an intercontinental and interdisciplinary network with the aim to elucidate the evolution of the molecular signaling and the crosstalk among different players that underpin the development of  fruit and fruit-like structures.  We will focus on:  a) the functional evolution of key transcription factors known to be integral for fruit and fruit-like development. To build the Fruit evolutionary conserved Genetic Regulatory Network (FGRN) we will consider core eudicots such as Aethionema arabicum, the orphan crops Lepidium campestre, Solanum lycopersicon and Passiflora edulis. We will include also non-core/early diverging eudicots: Papaver somniferum, and Aristolochia fimbriata and the gymnosperms Ginkgo biloba and Taxus baccata. b) the hormonal signaling involved in the coordination and synchronization of the steps of fruit/fruit-like development  c) cell wall pathways involved in pectin maturation and cellulose deposition required for fruit development.  We will use a broad set of approaches such as molecular genetics, evolutionary genomics, biochemical and biophysical analyses. The consortium will be engag
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Decomposition of multichannel surface electromyograms' (2002-2006), addressing dissemination and exploitation.

assistant: **Impact**

We propose to develop a prototype device for reliable and robust identification of clinically important muscle parameters out of non-invasively acquired surface electromyograms (SEMG) only.The project covers all aspects from basic research on compound signal decomposition techniques and SEMG signals, to the design and implementation of SEMG acquisition device. It is also highly multidisciplinary integrating the latest developments in signal processing with the state-of-the-art in neurophysiology.The main objectives of the project include- the design and implementation of 2D high-density electrode arrays, suitable for recoding the SEMG signals from different types of muscles,- the development and implementation of advanced procedures for automatic decomposition of SEMG signals into its constituent motor unit action potential trains,- validation and evaluation of the decomposition techniques on both synthetic and real SEMG signals, recorded in different conditions from different muscles.Decomposition techniques will be based on a completely novel blind source separation concept, enabling fast, robust and reliable estimation of signals constituting SEMG. Special care will be taken to enable the decomposition of noisy and underdetermined mixtures (i.e. mixtures with more sources than observations) of not strictly orthogonal sources, thereby significantly extending the limits of the state-of-the-art in blind source separation. The surface electrode arrays will include at least several tens of electrodes arranged in different matrix configurations.The project is expected to provide a novel, non-invasive and powerful tool for basic and applied research and clinical investigations in occupational, sport and rehabilitation medicine, ergonomics and space medicine, to have a high
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Decoding impairments of gait and balance from local field potentials in patients with Parkinson's disease.' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

Parkinson's disease (PD) is one of the most prevalent neurodegenerative disorders, affecting more than ten million people worldwide. Over the past decades, dopaminergic and surgical therapies have been optimized to treat upper-limb motor symptoms such as tremor, bradykinesia or rigidity with remarkable outcomes. However, these interventions are poorly effective to alleviate gait and balance deficits, which remain amongst of the most incapacitating symptoms affecting everyday mobility and quality of life in subjects with PD. Alternative stimulation strategies and novel surgical targets showed promises to improve gait. However, the lack of mechanistic insights and reliable readouts capturing the relationships between neural activity and leg motor dysfunction have prevented the development of effective, evidence-based therapies. Project gaitDCODE seeks to address these limitations. The objective of gaitDCODE is (i) to uncover the relationships between detailed patterns of gait deficits and the corresponding neural activity recorded from cortical networks and subthalamus nucleus in subjects with PD, and (ii) to leverage this knowledge to develop decoding algorithms that automatically predict these impairments in real-time. To enable these discoveries, gaitDCODE will build on two key innovations. First, it will exploit the conceptual and methodological expertise that the candidate gained through his work on gait rehabilitation after spinal cord injury, including high-resolution statistical approaches to capture the multi-faceted and time-varying characteristics of gait. Second, it will leverage the latest developments in implantable technology to sense and decode brain activity remotely and in real-time over extensive periods of time. In the long term, gaitDCODE will open up
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Lithium-ion battery with silicon anode, nickel-rich cathode and in-cell sensor for electric vehicles' (SeNSE).

assistant: **Concept**

The SeNSE proposal aims at enabling next generation lithium-ion batteries with a silicon-graphite composite anode and a nickel-rich NMC cathode to reach 750 Wh/L. Cycling stability is the key challenge for the adoption of this cell chemistry. The objective is to reach 2000 deep cycles by (i) reducing the surface reactivity of the active materials by a combination of novel film-forming electrolyte additives and active materials coatings, (ii) compensating irreversible lithium losses during the first cycles employing pre-lithiated silicon and providing an on-demand reservoir of excess lithium in the cathode, (iii) identifying and controlling critical cycling parameters with data provided from in-cell sensors. Adaptive fast charging protocols will be integrated into the battery management system based on dynamic in-cell sensor data and by implementing thermal management concepts on materials and electrode level. To improve the sustainability of the battery and to lower production cost, the content of the critical raw materials cobalt and natural graphite will be reduced. Enabled by protective coatings, aqueous slurry processing will be developed for the cathode. Costs will be further lowered and energy density improved by the development of thinner textured current collector foils offering enhanced adhesion. The feasibility and scalability of the SeNSE battery technology with respect to the call targets will be demonstrated through 25 Ah pouch cell prototypes and a 1 kWh module. Scalability to the gigawatt scale and cost-effectiveness of the proposed solutions, including aspects of recycling and second-life use, will be continuously monitored via regular briefings led by Northvolt, which currently undertakes one of the most ambitious efforts to establish a European cell ma