RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Toward fully physics based probabilistic seismic hazard assessment using physics informed neural networks' (TerraPINN), addressing dissemination and exploitation.

assistant: **Impact**

In regions of high seismicity, it is essential for society to understand the associated seismic hazard. A cornerstone of seismic hazard assessment is the ability to predict what kind of ground shaking occurs from a particular type of source at some given location; however, given the immense expense of full 3D viscoelastic seismic wavefield simulations, researchers typically rely on empirical relations that do not capture the path effects of wave propagation, which can significantly increase ground shaking by waveguiding and other effects. I propose to use a novel development in scientific machine learning - Physics Informed Neural Networks (PINNs) - to solve the 3D viscoelastic wavefield propagation problem. A fully trained network will drastically reduce the time required to compute the seismic response for arbitrary sources and receivers, enabling fully physics based seismic hazard in a probabilistic framework. PINNs utilize our knowledge of the physics, in this case the equations of motion for continuous media, to regularize learning, which reduces the required amount of training data by many orders of magnitude. We will utilize the PINN wavefield solver in a testbed study of physics based seismic hazard assessment for Southern California, with the goal of producing a framework that is computationally accessible to apply across the world.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'An integrated immunological and cellular strategy for sensitive TSE diagnosis and strain discrimination' to be submitted under Sixth Framework.

assistant: **Abstract**

Prion infections, or Transmissible Spongiform Encephalopathies (TSEs), result in progressive, fatal neurodegeneration. No effective therapies are available, and medical interventions, possibly including blood transfusions, have resulted in human-to-human transmission of prions. However, no biomarkers are available for preclinical diagnosis of prion infection in body fluids. All approved methods of diagnosis rely exclusively on detection of pathological prion protein (PrPSc), which may not be present in all TSEs. The TSEUR consortium proposes to develop, validate, and exploit innovative reagents and technologies that will address the above problems in three areas: (1) enhanced detection of PrPSc, (2) direct measurement of prion infectivity, and (3) validation of new TSE biomarkers in body fluids. Each partner brings into TSEUR a substantial body of existing knowledge and data, including a powerful new panel of picomolar-affinity anti-PrP monoclonal antibodies to a variety of PrP domains, which will provide the basis for highly sensitive detection of PrPSc and discrimination of prion strains ('epitope coding'). We will field-test the validity of our recently identified secreted surrogate markers, whose levels are profoundly increased in preclinical prion infections, for identifying potentially contaminated body fluids. Immuno-PCR technology will be explored as a means to enhance the sensitivity threshold of each assay. Finally, we will extend the scrapie cell assay technology for rapid and sensitive detection of bona fide prion infectivity in a variety of paradigms. Ongoing work indicates that all workpackages are highly feasible. The TSEUR program will develop innovative diagnostic technologies addressing the current gaps in prion detection, with the ultimate goal to enh
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'women's studies' (GENDERGRADUATES) targeting Sixth Framework.

assistant: **Abstract**

This is an EST proposal in the interdisciplinary area of gender and women's studies in the humanities and social sciences. Partners of 7 institutions with proven record of high expertise in gender research and education will jointly train and exchange PhD students. The training structure is: core curriculum of structured courses, some jointly taught by the partners, intensive training sessions, research seminars with emphasis on issues of interdisciplinary methodology, targeted tutorials and individual supervision sessions. Gender studies (GS) is according to the standard definition area adopted by the EU: the study, analysis and evaluation of the factors that affect the social, cultural, economic, intellectual and scientific status of women and minorities. Gender as a historical and cultural product affects personal identity, but also is a principle of organization of social structures and institutions; gender forms the basis for normative values and socially enacted meanings and representations. GS addresses theoretical and practical aspects of scientific research to contribute to a better understanding of the factors that delay the implementation of changes in the status of women and minorities. This field consequently involves also men and it defines 'wome n' as a category that includes differences of culture, religion, ethnicity, sexual orientation and age. Synergy is created between this EST and networks of GS that have been officially recognized by the EC (the Socrates Thematic Network ATHENA, coordinated by host), to ensure a prominent European dimension. The methodology is inter-disciplinary and involves both quantitative and qualitative comparative training methods. The EST gives high priority to the interest of the students and proposes a structured an d moni
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Defining the mechanisms by which platelets regulate neutrophil extracellular traps in sepsis'.

assistant: **Innovation**

Despite treatment advances, sepsis kills an estimated 150,000 in the EU annually. Lipopolysaccharide (LPS), neutrophils and platelets all participate in the pathogenesis of severe sepsis, but the inter-relationships between these players are poorly understood. Recently, we demonstrated that activation of neutrophils by platelets is necessary to defend against bacterial infection (Clark et al, Nat Med 2007). In response to endotoxaemia or bacteraemia, neutrophils lodged primarily in lung capillaries and liver sinusoids. Activation of platelets via the LPS receptor, Toll-like Receptor 4 (TLR4), induced platelet binding to adherent neutrophils. This resulted in robust neutrophils activation and the formation of neutrophil extracellular traps (NETs). Plasma from severely septic patients also induced TLR4-dependent platelet binding and production of NETs. These NETs retained their integrity under flow and ensnared bacteria both in vitro and within the liver and lungs. Activation of microbial defence mechanisms also caused tissue injury. We proposed that this novel bacteria trapping mechanism would only occur under extreme conditions such as severe sepsis, and that platelet TLR4 was the threshold switch. Although these studies implicate platelets in the regulation of innate immune function during severe sepsis, it is not yet known how TLR4 activates platelets nor how platelets stimulate neutrophils to release NETs. Experiments will address the hypothesis that platelets regulate the innate immune responses to bacteria through the following specific aims: 1) Investigate TLR4-dependent signalling events in LPS-activated platelets 2)Elucidate the mechanism by which LPS-treated platelets activate neutrophils to trap bacteria in NETs 3)Characterise NET formation in response to sept
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Research cooperation in assessment of microbiological hazard and risk in the food chain' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The main aim of MICRORISK is to establish the co-operation between the European Union (EU) and the third states in the area important from the public health point of view. The MICRORISK will provide the Ukrainian competent authorities the knowledge about the general principles of law and methods used for food examination at the EU and to implement it into the official food safety control process in Ukraine.The beneficiaries will have the opportunity to get know the Ukrainian situation concerning various aspects connected with food production for a better cooperation between the EU and outside the EU countries and for future harmonization of food law. Furthermore, the assessment of microbiological hazard and risk in the food chain in the EU and outside the EU countries will allow improve public safety in this area.The project will achieve these goals by the following steps:1. Analysis of the current food law at the different stages of food production chain (primary production, processing and marketing stages) existing in Ukraine and a possible implementation of the current EU food law into the Ukrainian microbiological food control process.2. Analysis and compare of methodology using for detection the most important food-borne pathogens in the EU and Ukrainian sides. Consider possible implementation and harmonization method used through both sides.3. Analysis of the prevalence of important microbiological hazard agents at different stages of food production chain in Ukraine basing on the existing microbiological data collection and food safety investigation resultThese activities will be performed by the series of common meetings, seminaries and exchange process of the representatives of competent authorities of the EU partners with the Urkrainian side. As the final resu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'IMproving Preparedness and RIsk maNagemenT for flash floods and debriS flow events' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The aim of IMPRINTS is to contribute to reduce loss of life and economic damage through the improvement of the preparedness and the operational risk management for Flash Flood and Debris Flow [FF/DF] generating events, as well as to contribute to sustainable development through reducing damages to the environment. To achieve this ultimate objective the project is oriented to produce methods and tools to be used by emergency agencies and utility companies responsible for the management of FF/DF risks and associated effects. Impacts of future changes, including climatic, land use and socioeconomic will be analysed in order to provide guidelines for mitigation and adaptation measures. Specifically, the consortium will develop an integrated probabilistic forecasting FF/ DF system as well as a probabilistic early warning and a rule-based probabilistic forecasting system adapted to the operational use by practitioners. These systems will be tested on five selected flash flood prone areas, two located in mountainous catchments in the Alps, and three in Mediterranean catchments. The IMPRINTS practitioner partners, risk management authorities and utility company managers in duty of emergency management in these areas, will supervise these tests. The development of such systems will be carried out using and capitalising the results of previous and ongoing research on FF/DF forecasting and warning systems, in which several of the partners have played a prominent role. One major result of the project will be a operational prototype including the tools and methodologies developed under the project. This prototype will be designed under the premise of its ultimate commercialization and use worldwide. The consortium, covering all the actors involved in the complex chain of FF & DF for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Optimizing KIWIfruit QUALIty through estimation of leaf stomatal conductance from sap flux density' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Most fruit crop irrigation scheduling is performed on empirical basis, with very little or no awareness of the consequences on yields and on water use efficiency. The main objective of this project is to obtain a model for the estimation of stomatal conductance through sap flux measurement in Actinidia, allowing assessment of plant’s water status and correct management of irrigation, while optimizing fruit quality. This goal will be reached through the following specific objectives: (i) to adjust models for estimation of leaf stomatal conductance of kiwifruit trees from measurements of sap flux density and atmospheric vapor pressure deficit; (ii) to understand which irrigation level optimizes fruit quality and productivity; (iii) to develop precision irrigation protocols based on stomatal conductance estimation. This project will lead to innovative results as it will (i) provide a model to estimate leaf stomatal conductance on an isohydric, drought sensible crop (kiwifruit) with high hydraulic conductance, allowing to understand the hydraulic limitations and physiological responses of one of the most water requiring crops; (ii) improve understanding on how a different plant water status and physiological performance at source level affects fruit yield and quality, and; (iii) provide a tool to optimize irrigation scheduling of Actinidia, based on estimated leaf stomatal conductance. While reaching these scientific objectives, Dr. Fernandes will acquire: (i) research skills by leading the project and being involved in the preparation of further proposal; (ii) teaching skills, by holding seminars and tutoring Master’s students; and (iii) networking skills, by participating at several meeting national and international working groups as well as through a strong interaction
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'innovaTive disbOnd aRrest features for loNg thermoplAstic welDed jOints' in the context of a Horizon 2020 call.

assistant: **Objectives**

The aerospace industry currently has a need for lightweight, complex composite structures to make their way into operational use. Changes in the regulatory landscape and demands for reduced emissions, coupled with the need to optimize Revenue Passenger Kilometers (RPK), have driven research efforts into cleaner, lighter, and more efficient aircraft designs. A key approach to reducing emissions is minimizing weight: by reducing weight, fuel usage drops, leading to a reduction in overall emissions. This requires that traditional materials such as steel, aluminum, and even titanium be replaced with lighter, high-performance materials. High Performance Thermoplastics (HPTP) are an excellent solution to the issues of recyclability, light weight, high performance, and repairability. HPTP composites offer compelling advantages over metal components: improved working life, lower weight, reduced fuel consumption, and longer service intervals.The Large Passenger Aircraft (LPA) Platform 2–Multifunctional Fuselage Demonstrator (MFFD) will employ new combinations of airframe structures, cabin/cargo, and system elements using advanced materials, notably HPTP composites. The MFFD is focused on achieving significant cost and weight reductions, coupled with high production rates. The use of thermoplastic welding can lead to significant benefits, but in order to obtain certification under EASA and CS 23 rules, disbond arrest features must be integrated into the structure.The TORNADO project will develop a novel technology, Inductive Low-Shear Friction Stir Riveting, as well several other fallback alternatives, in order to provide a high-performance solution for disbond arrest in the MFFD.


**Keywords:** thermoplastic welding disbond induction rivets
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Applying open standards to INNOVAte FUrNiture business processes' (INNOVAFUN), addressing dissemination and exploitation.

assistant: **Impact**

INNOVAFUN will build industrial consensus on the innovative funStep standard-based solution, facilitating the integration of open standards in the furniture industry into the design of new products and services. The project identifies new services for a better improvement in business processes, implementing an action plan for its harmonization, and delivering outreach activities supported by focused user-oriented material.INNOVAFUN strategic objectives are:- Facilitate SME's integration and adoption of the funStep standard-based solutions- Lead SMEs to a better position in the competitive global market, stimulating the innovation by improving their business processes- Develop and execute an action plan for the exploitation of the funStep standard by promoting business practices and services and providing practical guidance for their implementationThe objectives will be achieved through:- Identification and evaluation of common business process requirements to help companies becoming more competitive- Building on innovative solutions, facilitating the integration of the funStep standard into the design of new business practices and services and supporting novel business networking activities- Implementing Outreach actions to provide the furniture industry with complete awareness on the advantages of integrating funStep standard-based solutions
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Esh-tbm' to be submitted under Fifth Framework.

assistant: **Abstract**

The transplantation of cells, tissues and organs is a rapidly evolving field of scientific knowledge and medical practice worldwide. Clinical applications include haemopoietic malignancies, immuno-deficiencies and organ failure. Transplantation also holds strong therapeutic potential for many other chronic degenerative diseases. The extreme genetic diversity of the European populations (donors/recipients), the specificities of Europe's national Public Health systems, and the fact that the legal, ethical and societal issues posed by basic and clinical research/practice in this field vary throughout Europe, all confer unique characteristics to the practice of transplantation biology/medicine in Europe.Transplantation biology/medicine is a complex, integrated field that requires a multidisciplinary approach to the genetics and the molecular/cellular immune mechanisms controlling graft acceptance and optimal long-term function. A full understanding of the immunogenetics and histocompatibility governing all reactivity is a prerequisite for optimal matching of donors and recipients. Haemopoietic and organ transplantation, as well as the fields of cancer, autoimmune and inflammatory diseases, and allergy will benefit from innovative immuno-intervention (tolerance induction, immune deviation and suppression, specific vaccination and immuno-modulation) solidly founded on basic concepts and experimental research. Despite excellent European basic research and transplant centres, to date no European forum for high-level training exists in this field. This proposal concerns the creation of a multidisciplinary forum for basic and clinical scientists working in the academic and industrial settings, at the junior and senior levels. It also intends to promote reflection, at the European