RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The role of tanycytic cilia in hypothalamic functions.' (TanyCilia) under Horizon Europe.

assistant: **Objectives**

Obesity and metabolic diseases are a top priority challenge for health systems. Monitoring changes in the bodys energy levels is a task of the hypothalamus (HpT) which integrates the actions of peripheral hormones and nutrients with neural information. However, this regulation is complex, and the causes and biological mechanisms leading to metabolic disorders remain to be explored. Among the cells involved, tanycytes play a key role. They are glial cells that line the third ventricle and mediate information about changes in the circulation to various HpT nuclei. They regulate important neuroendocrine functions such as food intake and energy balance. Although tanycytes are known to integrate external and internal signals, the specific cellular organelles through which they sense these cues remain unknown. Primary cilia (PC) are one such compartment crucial for perceiving peripheral signals, and they are indeed present in tanycytes. We have coined the name tanycilia for them. However, the function of tanycilia is still unclear. Here, we hypothesize that cilia may act as antennae for tanycytes, sensing nutrients or hormones, enabling adaptive cellular responses, and transmitting metabolic information to neurons. This project aims to I) characterize tanycilia morphology for the first time; II) identify their functions, primarily in the regulation of metabolism; and III) examine them in pathological contexts like obesity and anorexia. To achieve these goals, we will employ immunohistochemical techniques to characterize tanycilia in wild-type mice. To investigate their function, we will genetically manipulate tanycilia using inducible mouse models in combination with tanycyte-specific adeno-associated viruses (rAAV). The discovery of tanycilia's roles in integrating periphera
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Metabolic sensor proteins that couple essential cellular processes and primary metabolism' in the context of a Seventh Framework call.

assistant: **Objectives**

How are we what we eat?How are essential cellular processes coordinated at the level of protein activity in response to nutritional changes? This is the broad question my research seeks to understand.Metabolic pathways building the cell bricks are extensively described. By contrast, our understanding of the molecular mechanisms driving cell-wide processes is recent and incomplete. This explains why the regulatory links between these cellular processes and primary metabolism are largely unexplored. State of the art methods, in particular in cell biology, now provide the means to address this fundamental question. Investigating these connections are best carried out in simple well defined systems. My research uses the model bacterium Bacillus subtilis. It is a Gram positive rod-shaped bacterium that is genetically amenable.In this project, we propose candidate and innovative large-scale approaches to identify and characterize metabolic sensors at the heart of these regulations. First, we will characterize a candidate protein that is expressed in the same operon as a metabolic enzyme and which absence affects cell division. We will also take advantage of this time to setup a high-throughput fluorescence microscopy workflow and transfer tools from my post-doctoral laboratory, hire students and formalize collaborations in Europe and the United States. Second, the main part of this project will concentrate on the identification and the characterization of new proteins coupling morphogenesis, division and chromosome dynamics to carbon and nitrogen metabolism. An interdisciplinary approach combining modern techniques in fluorescence microscopy, genetics, genomics, bioinformatics, biochemistry and automation will be used to study these metabolic sensors. Understanding the connec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Discretion and the child´s best interests in child protection' to be submitted under Horizon 2020.

assistant: **Abstract**

DISCRETION aims to unlock the black box of discretionary decision-making in child protection cases by a comparative-empirical study of how discretionary decisions are made and justified in the best interests of the child. There are huge research gaps in this important area of the welfare state, with a great deal of uncertainty concerning how, when and why discretionary decisions about the child´s best interests are different between decision-makers within and between child protection systems.The main objectives for this project are to reveal the mechanisms for exercising discretion, and improve the understanding of the principle of the child´s best interests. These objectives will be reached by systematically examining the role of institutional, organisational and individual factors including regulations of best interest principles; professions involved; type of courts; type of child protection system; demographic factors and individual values; and the populations’ view on children and paternalism. DISCRETION employs an innovative methodological approach, with multilevel and cross-country studies.DISCRETION will, by conducting the largest cross-national study on decision-making in child protection to date, lift our understanding of international differences in child protection to a new level. By conducting randomized survey experiments with both decision-makers in the system and the general population, DISCRETION generates unique data on the causal mechanisms explaining differences in discretionary decisions. The outcomes of DISCRETION are important because societies are at a crossroad when it comes to how children are treated and how their rights are respected, which creates tensions in the traditional relationship between the family and the state. DISCRETION will move
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Tracing the oceanic mechanisms for the deglacial increase of atmospheric CO2: the role of Southern Ocean ventilation' (DeglacialCO2).

assistant: **Concept**

It is now well documented that atmospheric carbon dioxide concentration (pCO2) changed in parallel to the growth and decay of polar ice sheets over the last 800,000 years. However the mechanisms that cause these variations in CO2, and exactly how they are related to Earths’ climate remains much debated. This is a crucial issue given the current anthropogenic increase in pCO2 and it was recently identified by the IPCC as a key uncertainty in our understanding of the climate system as a whole. Although the exact processes are contested based on the magnitude and rapidity of the rates of carbon exchange, it is generally accepted that changes in oceanic carbon storage play a vital role in causing glacial-interglacial CO2 change. The overall aim of this proposal is to better understand the role of intermediate waters ventilated in the Southern Ocean in the rise of CO2 during the last deglacial.To achieve this aim, we will use the boron isotope-pH proxy in planktic foraminifera from a suite of key locations (Southern Ocean and Equatorial Pacific) to reconstruct oceanic pH changes during the last deglaciation, with the objective of documenting where and when CO2 was leaked to the atmosphere from the deep Southern Ocean during the deglacial. The generated data will be then tested against a new model output of the GENIE Earth System Model, in order to determine the relative importance of the deep carbon reservoir in driving Glacial-Interglacial CO2 change.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Molecular and morphological systematics of the Polyporales, a highly diverse, poorly documented clade of wood-decaying fungi with biotechnological potential""' (POLYSYST) targeting Seventh Framework.

assistant: **Abstract**

The research focus of this project is systematics of the Polyporales, a diverse clade of the basidiomycetes. The Polyporales play a dominant role in timber decay in nature, and their ability to enzymatically decay wood is under intense research for biotechnological uses. Yet no phylogeny or modern classification exists for the Polyporales. This project will produce both.University of Helsinki has a long tradition in morphology-based research of the Polyporales. Dr. Otto Miettinen, the fellow, has been trained in that tradition. During the 12-month outgoing mobility he will visit Prof. David Hibbett's lab in the Clark University, USA. Prof. Hibbett is the leading name in molecular systematics of basidiomycetes. During his stay Dr. Miettinen will utilise Prof. Hibbett's expertise in state-of-the-art molecular techniques, including genome sequencing. During the home-coming phase the fellow will continue his studies in the vibrant community of mycologists in Helsinki under the guidance of Prof. Soili Stenroos, a senior fungal systematist.During the outgoing phase the fellow will produce phylogeny for the Meripilus clade, a species-rich and very poorly known part of the Polyporales. He will undertake collecting in North America and the tropics in order to screen for species unsampled in phylogenetic studies. During the home-coming phase the fellow will revise classification in the Meripilus clade, and participate in a meta-analysis on the phylogeny and character evolution of the Polyporales.The mobility will boost Dr. Miettinen's career very significantly. He will absorb cutting-edge molecular methods, author at least two very influential papers in the field, accumulate a highly valuable dataset of sequences and specimens, and be able to associate and network with leading na
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Study of magnetic responsive biopolymer based materials' (MAGBIOMAT).

assistant: **Innovation**

The aim of the proposed project is to synthesize and characterize new nanostructured magneto-responsive biopolymer-based materials by the introduction of functionalized magnetic nanoparticles in biogel and foam to gain a deeper understanding of two fundamental aspects: - The understanding of the formation mechanisms of such structures: magneto-responsive networks. - The correlation between the behaviour of the nanostructured composite biopolymer-based materials under the change of external conditions, such as magnetic field, shear, ionic strength, pH and composition of polymer and magnetic nanoparticles or the chemical structure of the constituents. The research project will involve different aspects. On one hand, it will include the elaboration of new magnetic-responsive biopolymer-based materials. On the other hand, the project will try to develop specific dedicated apparatus, allowing the measurements of mechanical properties under magnetic field to determine structure and dynamical properties at different external conditions as well as kinetics of structure transformation of such systems controlled by magnetic field. The combination of synthesis, characterization and theory will allow a synergy for the elaboration and optimization of novel magnetic-responsive biopolymer based materials with fine tuned properties and for their future application in industry (vehicle for drug delivery, intelligent materials for medical and structural applications).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Libralato rotary engine; a game-change for cost competitive gasoline engines and plug-in hybrid cars.', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The Libralato engine is the world’s first “one stroke” rotary Atkinson cycle engine, completing all of the engine phases in parallel in each rotation. It has a completely new thermodynamic cycle which is predicted to achieve around 40% efficiency using gasoline. This is achieved because of its asymmetrical expansion and compression volumes and because it does not need to convert the reciprocating motion of pistons into the rotational motion of the output shaft. The Libralato engine has only four principal moving parts: two rotors fixed by their own bearing, connected by a sliding vane and a rotating exhaust. It has no need for conventional cylinders, pistons, con-rods, crankshafts, valve trains and cam shafts. The engine is tuned for lean burn combustion, with high and constant levels of torque, very low vibration and very low exhaust temperature and noise reducing fuel consumption by two thirds and CO2 emissions by 50%.The proposed innovation project intends to; demonstrate and validate the performance of the engine in an operational environment; run a fully operation commercial pilot with fleet test; industrialisation of Libralato engine for high volume production; scaling of production capability for up to 20k units.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'PROtotypes of Magnetic Imaging Systems for Europe' (PROMISE) targeting Horizon Europe.

assistant: **Abstract**

PROMISE is a consortium that focuses on the application of Nitrogen Vacancy (NV) in diamond quantum technology for imaging. The aim is to guide the development and use of this mature and promising quantum technology, which is known for its ease of operation.PROMISE leads the NV based quantum imaging sensors to the next level of development building widefield magnetometer prototypes to measure relevant samples into operational environments (TRL7) to foster its market uptake. The PROMISE widefield NV magnetometer excels in imaging compared to other technologies by generating magnetic field maps without scanning. This results in a faster acquisition time (orders of magnitude faster than scanning protocols), a wide field of view and increased sensitivity. This speed up in the acquisition is the key to open up its use in a wide range of new applications.The consortium is committed to leveraging the developed NV-based prototypes for a consolidated market uptake by involving relevant partners along the whole value-chain. A unified, compact, affordable and low-consumption benchtop prototype will be designed and developed without impacting performance and functionalities. Machine learning software is being developed to streamline both data acquisition and data analysis, to facilitate for non-quantum expert use of the device and paving the way to automate inspection process. PROMISE also includes expertise that will contribute to standardising designs and methods required for the industry.During the project, four use cases will validate the prototypes, impacting the semiconductor industry, material science, aerospace and biotechnology. The industry, in general, will benefit from a tool that will enable improvements in their devices, materials and production processes, as well as
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'HeliconPlasmaHydrazine.COmbinedMicro' (2007-2013).

assistant: **Concept**

The objective of the research program is to design, optimize and develop a space plasma thruster based on helicon-radio-frequency technology and its application to a nano-satellite for attitude and position control. Moreover a detailed feasibility study will be also conducted to evaluate the possibility of using the plasma thruster to heat and decompose a secondary propellant. The feasibility study will asses the possibility of building up a combined-two-mode-thruster able to operate in the low-thrust high-efficiency plasma-mode and high-thrust low-efficiency secondary-propellant-plasma-enhanced mode. Only the plasma thruster will be developed and fully tested during this study. The main characteristics of the thruster are: Power 50 W Weight within 1.5 kg Thrust >1.5 mN Specific Impulse (Isp) >1200 s  The program will develop thought the following steps: a) Deep numerical-theoretical investigation through dedicated plasma-simulation tools. b) Extensive experimental campaign to validate codes, to investigate the physics phenomena involved and to proof thruster performance. c) The development of a thruster-prototype to be mounted on board of a mini-satellite to demonstrate technology feasibility, d)The study of all the critical issues related to the application to a mini-satellite e) the design and manufacturing of the mini-satellite mock up including all critical components f) analysis of scaling law to lower and higher power. As a final results of the project, a detailed analysis will be conducted in order to evaluate the possible application of the thruster in space missions requiring low thrust accurate attitude and position control.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Democratising digital farming through tailored open source and open hardware solutions' under Horizon Europe.

assistant: **Concept**

The last decade has seen an explosion of interest and investment in the use of Agricultural Digital Technologies (ADSs). The use of ADSs is seen by many as an opportunity to increase the economic and environmental performance of the agricultural sector. Despite great efforts and resources spent, uptake of ADSs by EU farmers has been limited for reasons like a) the frequently excessive cost of ADSs, b) the low trust that farmers have on ADSs and data sharing, for a variety reasons, and c) the weak network connectivity problems experienced by farms in remote areas, which affect the performance of the ADS. The overall aim of the OpenAgri project is to democratise digital farming by enabling the development and deployment of innovative cost-effective energy-efficient OS software and open hardware-based ADSs that can operate at a high performance even in remote areas with weak connectivity. This will be achieved by a) ensuring the co-creation of ADSs by engaging farmers and farm advisors in participatory prototyping activities inspired by the makerspaces approach; and b) providing access to a number of reusable OS software services designed to support the edge and mixed computing mode, and a “sociotechnical infrastructure”.Using a multi-actor approach, OpenAgri will involve farmers, ADSs providers, farm advisors and scientists in 14 Sustainable Innovation Pilots (SIPs) in ≥10 countries across Europe, and guide them in co-creating and piloting edge, cloud and mixed-model ADSs addressing important challenges of agricultural production. 5 SIPs have been pre-selected and 9 more will be awarded through an Open Call, enabling a dynamic response to a changing policy and technology landscape. Finally, building on a thorough analysis of EU agriculture and the results from the SIPs, O
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'SUCCESS- successful travel awareness campaigns and mobility management strategies', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

Mobility Management (MM) and Travel Awareness (TA) have many advantages as soft policy strategies: they are flexible, adaptable, rapid to implement and offer value-for-money. Many sustainable transport research projects have covered MM and TA, but in isolated projects, limited to larger cities and pilot demonstrations. SUCCESS now offers the chance to link these two areas and exploit their synergies, based on its research areas: A Innovative Approaches in TA B Behaviour Change Models and Prospective Assessment C Quality Management and MM For Smaller Cities D Integrating Planning and MM.They will be linked via horizontal WPs: WP 1 State-of-the-art analysis WP 2 Conceptualisation and specification of research activities WP 3 Monitoring investigations and implementation WP 4 Compiling results WP 5 Dissemination and WP 0 Project Management, Quality Control and Evaluation run in parallel for the duration of the project. Organising the work in this way will deliver excellent results.