RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Research project proposal for the development of integrated aeroponics systems', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The present proposal aims at developing an innovative aeroponics system that, on the one hand, reduces the costs of investment and therefore can make the system accessible to SMEs as well, and on the other grows simultaneously a number of different horticultural and floricultural crops while maintaining the same high quality. The innovative solution will consist of the following: . the use of very simplified and fully recirculating nutritious solutions (i.e., starting from and returning to the same point and not starting in one container and ending in another) with monitoring and replenishment of the solutions; . innovative distribution and structure of the system in the available area to obtain the most efficient use of available space, achieving minimisation of unproductive tares within the greenhouses to approximately 10% of the soil (from an average 35-40% of existing methods) . the use of a computerised system to control the climate in the greenhouse and the components of the nutritious solution Through the innovative solutions here proposed, it will be possible to realise an aeroponics system at limited cost and with substantial gains in terms of environmental protection, profitability, saving, organisation of agricultural labour and versatility.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'New therapies for uveal melanoma' to be submitted under Horizon 2020.

assistant: **Abstract**

Uveal melanoma (UM) is a rare intraocular tumour with an incidence of 5 cases per million individuals per year. Up to 50% of UM patients develop metastases, most often in the liver, and these are invariably fatal. Despite new discoveries in the genetic and molecular background of the primary tumour, little is known about the metastatic disease; furthermore, there is no therapy to either prevent or treat UM metastases. In UM Cure 2020, we aim to identify and validate at the preclinical level novel therapeutic approaches for the treatment of UM metastases. For this purpose, the consortium brings together the major experts of UM in both patient care and basic/translational/clinical research, as well as patient representatives. An ambitious multidisciplinary approach is proposed to move from patient tissue characterisation to preclinical evaluation of single or combinations of drugs. This approach includes the characterisation of the genetic landscape of metastatic UM and its microenvironment, proteomic studies to address signal pathway deregulation and establishment of novel relevant in vitro and in vivo UM models. We also aim to validate accurate surrogate endpoint biomarkers to evaluate therapies and detect metastases as early as possible. Underpinning this will be the UM Cure 2020 virtual biobank registry, linking existing biobanks into a harmonised network, which will prospectively collect primary and metastatic UM samples. Together, our approach will lead to the identification of new therapies, allowing the initiation of UM-dedicated clinical trials sponsored by academia or pharma. Dissemination of results will include the building of a patient network across the countries as part of the consortium as well as a dedicated UM patient and caregiver’s data portal as part
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Development and implementation of an innovative cleaning technology for marine and freshwater larval hatchery tanks in recirculating aquaculture systems' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The current lack of cost-effective and efficient cleaning technologies in both freshwater and marine larval hatchery tanks in recirculating aquaculture systems is a substantial drawback for both technology-providing and fish farming SMEs in Europe. Bacterial biofilms constantly and quickly develop on all surfaces in the tanks and endanger the production of high quality and quantity fry which is an absolute must for successful aquaculture operations in a growing, highly competitive market. Thus, there is an enormous need to find a sustainable technology for an efficient cleaning of the tank surfaces and the standpipe meshes. Meshes on the standpipe, which prevent the aquatic life from being sucked away from the water flow, need to be continuously replaced due to the formation of biofilms, resulting in high material and labour costs. CLEANHATCH aims to develop and implement a new technology that constantly sweeps the sides and base of the tanks as well as backwashes the meshes whilst injecting ozonated water into the tank directly over the tank surfaces. Compared to the state of the art, the new technology has the advantages of (a) cleaning the tank's sides, base and standpipe's meshes saving considerable man-hours, (b) disinfecting the surfaces and meshes through the focused injection of the ozonated water, (c) reduce the amount of mesh required and focus the mesh to the bottom part of the tank where the water is best extracted from. CLEANHATCH will develop, implement, test and optimise the new technology under pilot and real production conditions, aiming to achieve a marketable product within one year after project termination. The project is centred on complementary technological problems and innovation needs of the three participating SMEs. By providing technology app
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Arctic Demonstration and Exploratory Voyage' under Fourth Framework.

assistant: **Concept**

ARCDEV project is a Short Sea Shipping (SSS) full scale demonstrator. It will concentrate on the operational and technical feasibility as well as on the cost-effectiveness of a SSS corridor linking all the year round the Arctic regions of Russia to the EU. The verified oil and natural gas reserves in Northern Russia and in the Russian sector of the Arctic Ocean are very large. They are considered as one of the long term energy supply source of Western Europe.Together with western oil companies and engineering firms Russia is in the process of developing technologies to produce and ship most of the oil to Western Europe. Instead of transporting the oil by pipelines through various foreign countries and across unsafe soil conditions, the industry would like to investigate waterborne transport possibilities.The conditions for maritime operations are extremely harsh in this region. While the Port of Murmansk never freezes, ice conditions become progressively more difficult eastward. East of the Taymyr Peninsula the route is covered by thick ice throughout the year. In the western part up to Novaya Zemlia the ice conditions are comparable to those encountered in the Northern Baltic Sea. Generally the period of 3 to 6 months is navigable under open water conditions.The project will be implemented through a fully operational winter test voyage to the Ob river estuary with two ice strengthened vessels: an EU member state flag vessel and a Russian one. The test voyage will be performed in the form of real transportation, delivering gas condensate from the Ob Bay area to the European market.The main objectives of the Demonstration and Exploration Voyage are concerned with- Year round navigation in the Arctic- Safe, reliable and economical operations- Commercial aspects of such tr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'European economic impact study for the European shipping sector (e-eis)' in the context of a Fourth Framework call.

assistant: **Objectives**

1. The description of a methodology for the assessment of the economic impact of the shipping sector activities on the Member States' and the European economy: the European Economic Impact Study.The E-EIS methodology allows the quantification of the full economic significance of the shipping sector in the EU. The E-EIS also provides essential information with respect to the linkages between the sector concerned and other economic sectors. First, a framework will be developed which can be used for all Member States, and second, a method will be described for the construction of the Input-Output-tables (the bottom-up method).2. The construction of the Input-Output-tables for the Netherlands, Belgium, UK and Italy.First, the shipping sector and its sub-sectors need to be determined and data need to be collected for the construction of these tables. Second, the data will be used to construct the Input-Output-tables for each of the four Member States.3. The quantitative evaluation of the shipping sector in the Netherlands, Belgium, UK and Italy, using the E-EIS methodology.The inter- and intra-sectorial relations between the shipping sector and the other sectors of the economic system will be analysed as well as the total economic impact of the shipping sector in terms of value added, employment and backflow to the government.4. The development of a set of relevant recommendations for a European shipping policy and the assessment of the potential effects.Emphasis on the possibility of identifying a common response to changes in the global environment. The economic impact of a number of policy scenarios will be calculated according to the E-EIS methodology. Three scenarios will be considered: the laissez-faire scenario, the conventional subsidiation scenario and the new polic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Ship Evacuation Data and Scenarios'.

assistant: **Concept**

The collection of human performance data in full-scale ship trials is vital for the calibration and validation of ship based evacuation models.  The IMO Fire Protection Sub-Committee in their modification of MSC circ 1033 at the FP51 meeting in February 2007  invited member governments to provide, “…further information on additional scenarios for evacuation analysis and full scale data to be used for validation and calibration purposes of the draft revised interim guideline.”  The purpose of SAFEGUARD is to address this requirement by providing (a) full-scale data for calibration and validation of ship based evacuation models and (b) propose and investigate additional benchmark scenarios to be used in certification analysis.  The results of both of these tasks will be reported to IMO for possible incorporation into future modifications of the MSC Circ 1033.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Distributed Supervisory Control of Large Plants' (DISC).

assistant: **Concept**

Supervisory control is a formal approach for the control of discrete event systems that aims to solve logical problems of safety, resource allocation, liveness, and fault diagnosis that can be encountered in all systems with a high degree of automation. It provides a conceptual framework for developing methods and tools for system design.<br/><br/>An open issue is the application of this methodology to those control problems that arise in networked embedded systems. These distributed plants are composed by several local agents that take concurrently decisions, based on information that may be local or received from neighbouring agents; they require scalable and self-organising platforms for advanced computing and control..<br/><br/>An important feature of this type of processes is the possibility of studying them at an appropriate level of abstraction where the resulting model is a purely discrete event one. The evolution is guided by the occurrence of asynchronous events, as opposed to other real-time models where the event occurrence is time-triggered.<br/><br/>We plan to use several techniques to reduce the computational complexity that is one of the major obstacles to the technology transfer of supervisory control methodologies to distributed plants. These techniques are: modularity in the modelling and control design phases; coordinating control; modular state identification and modular fault detection based on the design of decentralized observers; fluidisation of discrete event dynamics to reduce state space cardinality.<br/><br/>All the partners have been very active in this area and in many cases bilateral collaborations are already active. The idea of the project is to:<br/>- provide a forum for the discussion and dissemination of results;<br/>- develop a comm
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Segmentation for Transport in Markets using latent user psychological structures' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Successful implementation of traffic management measures to establish an efficient communication between decision takers, transport users and citizens is crucial. Conventional classifications have proved not to reflect similarities in decision taking processes well. Approach: 1. Particular types of users, representing market segments will be classified (Conventional classifications). Their interests, attitudes/motivators and behaviour towards communications of transport information and transport management measures, the implications of mobility restriction and attitudes and understanding of environmental and external costs will be identified.2. New categories of users according to underlying psychological processes will be identified, and these will be cross-tabulated with known demographic and end-user types. Interests, attitudes/motivators and behaviour of these newly defined cross-category groups towards traffic and transport management measures will then be identified as well as the implications of mobility restrictions and attitudes/understanding of environmental costs.3. Information systems, policies and strategies will be assessed for their level of acceptance or rejection by different user groups according to both methods of classification. Risk in planning will be reduced by enabling information systems, policies and strategies to be assessed for the reasons for their acceptance or rejection by different user groups according to those groups' perceptions of the social and environmental 'cost' of transport, (pollution, infrastructure etc.)4. The extent to which information systems in the study contribute to, or are associated with opportunities for will be assessed:Better and safer travel, travel planning, transparency and user-friendliness of systems.5. To make
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'POLYmer-COntrolled Mesocrystal application-oriented Production: a combined theoretical and experimental approach.' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

POLYmer-COntrolled Mesocrystal Production (POLYCOMP) aims to develop an intimate understanding of the underlying mechanisms of mesocrystal formation. This in turn will lead to the development of new mesocrystals with controlled morphologies and thus optimised properties. Mesocrystals have only very recently been described and are best viewed as an entirely new class of material. As such these unique substances have the potential to revolutionise materials/devices containing inorganic components. Applications are myriad and include building materials, such as concrete, with vastly greater compression strengths (in theory at least, the heights of concrete buildings could be increased from 500m to 15km!), solar cells with far higher solar harvesting efficiencies, new biomimetic materials, e.g. for use in joint replacement procedures, and electronic devices where size-dependent nanoparticle-like properties, e.g. superparamagnetism, are retained in macroscopic-sized materials enabling easier manufacture of components such as computer memory, quantum dot-based LEDs, etc. Currently approaches to mesocrystal formation are somewhat ad hoc and these kinds of application remain largely unachievable. The principle underlying reason for this is that mesocrystal formation processes are often still too poorly understood. POLYCOMP will remove this bottleneck to mesocrystal exploitation by focusing directly on developing a generic understanding of mesocrystal formation processes. Such an approach is thus clearly directly relevant to the EU’s mission to advance knowledge and technology in areas such as construction, electronics and energy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Synthesis, redox properties and conformational studies of multiple cystine/ selenocystine containing peptides' (1994-1998).

assistant: **Innovation**

Research objectives and content The diselenide bridge will be analyzed as mimetic of the disulfide bridge in term of oxidative folding behaviour and conformation of poly-cystine containing peptides. Endothelin- 1 and Apamin, with two intrachain disulfide bridge, are choosen as model peptides. With the rational substitution of one pair of cysteines with one pair of selenocysteines each time, formation of all possible monomeric conformers (globule, ribbon and beads) of these peptides will be induced and the conformations of the resulting fully and partially oxidized peptides will be investigated in order to define the conformational aspects of oxidative refolding pathways. Conformational constraints will be applied to fragments peptide of the active site of four thiol protein oxidoreductases (PDI, grx, grr, trr), in the attempt to modulate in a favorable manner their redox potential for their use as PDI-like synthetic enzimes or folding adjuvants for recombinant proteins. Training content (objective, benefit and expected impact) My primary objective during this training is to acquire a deeper knowledge on the chemistry and biochemistry of cystine containing peptides that is still one of the more challenging fields in peptide chemistry. The contribution of Prof. Moroder in this field is worldwide known. I will also deal with other important biophysical aspects in peptide and protein chemistry, such as protein folding pathways and related conformational studies, to complete my training. Links with industry / industrial relevance (22) The correct oxidative folding of recombinant proteins still represent one of the major drawbacks for the industrial production of proteins as drugs. The development of low mass redox-active peptides with tunable redox potentials as folding adju
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Model theory, locally compact groups and solution of Hilbert's 5th problem'.

assistant: **Concept**

The main goal of the project is to apply advanced techniques from the model theory (a branch of mathematical logic) to the class of locally compact groups arising from the solution of Hilbert's 5th problem (so at the end, to the class of Lie groups), to answer the following question: how much geometry can model theory recognize? There does not exist a general (first-order) model-theoretic description of the locally compact groups, thus our first goal will be to develop such a description. Then, we will study how notions from these two corners of mathematics, i.e. model theory and locally compact groups, correspond to each other. For example, we will try to enrich the classification of locally compact and Lie groups by translating the dividing lines from the model-theoretic stability hierarchy. In the next stage, machinery from the so called geometric (neo)stability theory will be deployed in a tame class of locally compact groups, for example in the class of locally compact groups being projective limits of Lie groups and not having small subgroups (so in the groups from the solution of Hilbert's 5th problem). In this spirit, one could consider the definable homogeneous space coming from the Group Configuration Theorem, which is a part of the aforementioned machinery, and try to relate it to the unsolved Hilbert-Smith conjecture - this will be one of our milestones.In short, we aim to find connections between model-theoretic theorems of geometric nature and classical theorems on the Lie groups, so theorems which depend on the geometry of Lie groups. After understanding these connections, we want to transport techniques from the model theory into the locally compact and Lie groups and vice versa.


**Keywords:** model theory, geometric stability theory, locally compact g