RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Early defects in the dynamic of the spinal sensorimotor network: is ALS a post-natal neurodevelopmental disorder ?' (ADELE), addressing dissemination and exploitation.

assistant: **Impact**

Amyotrophic lateral sclerosis (ALS) is a fatal and incurable neurodegenerative disorder caused by the loss of motoneurons in the brain and spinal cord. Each year, ALS is responsible for three-five deaths per 100000 people. ALS initiates in mid-life by muscle weakness, evolving rapidly into a generalized paralysis that leads irrevocably to death within 2-3 years of clinical onset. Despite an exploding knowledge of pathological processes acquired in adult subjects, successive clinical failures suggest that our way to consider and treat the pathology may not be the most pertinent and effective. The idea that the pathology can originate during development has received very little attention, while in the post-natal period the fundamentals of the sensorimotor system are being laid, its completeness will be central for the rest of our days.  ADELE project proposes to explore ALS as a developmental disease that take roots during critical developmental stages when the synchronized activity of sensorimotor circuits is established, and that subclinical threshold defects remains silent before reaching a clinical break point. This conceptual progress, with diagnostic and early therapeutic implications, can be made possible with the recent access to network activity of the spinal cord in rodent neonates. ADELE proposes to 1) investigate the spatiotemporal network dynamics in ALS mouse neonates by recording field activity using multi-electrode array along the spinal laminae, 2) to complete this approach by behavioral study of proprioceptive integration, which is detrimental for spinal circuitry function and 3) identify activity modulating drug to restore early spinal network dynamics and subsequently influence the course of the disease. Our multidisciplinary strategy will fill knowled
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'SUSTAINABLE REFURBISHMENT WITH NEW EFFICIENT TECHNOLOGIES IN RESIDENTIAL BUILDING WITH ENERGY SUPPLY' (SURE-NET) under Fourth Framework.

assistant: **Objectives**

Aim: a) implementation of a high efficiency MVHR unit with DC fans and b) replacing of block heating by a cogeneration plant integrated with a solar thermal system. Both a) and b) will be retrofitting processes in post war social housing in Heerlen, the Netherlands.Aspects presented as innovative: 1) use of a newly developed, high efficiency heat exchanger together with DC fans, for mechanical ventilation and heat recovery (MVHR), ensuring minimum energy consumption 2) combination of cogeneration plant with a large solar thermal system and 3) exploitation of the above combination by local utilities.Housing corporation Heerlerbaan in the Netherlands and KOWO in Erfurt, Germany have many representative post war residential buildings for social housing with serious problems in the field of high energy use due to thermal losses and inefficiency of heating systems as well as poor indoor air quality as a result of poorly functioning ventilation systems. As many of these residential buildings space heating is delivered by energy supply. In Erfurt by district heating; in Heerlerbaan by central block heating.There are two major benefits to maintain the principle of energy supply: · Efficient combined generation has more environmental benefits regarding to primary energy use and CO2 emission.· Maintaining the infra and distribution structure keeps the possibility open for the future to use sustainable and/or renewable energy sources, fuel cells etc.In project Heerlerbaan the central boilers are replaced by a small scale co-generation plant. Ventilation losses are strongly reduced by applying a new development in MVHR (laminar counter flow exchangers with an energy efficiency of >90%). Also support energy is reduced with 50% by using DC fans. MVHR also guarantees high IAQ in airti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'A novel and easy to interpret patient safety monitor, for the diagnosis and management of cardiac function, fluid delivery and drug administration during surgery and intensive care.' (TruVue) under Horizon 2020.

assistant: **Objectives**

Worldwide 234 million patients undergo major surgery annually. One million will die within 30 days. A further 42 million simply die up to 13 years sooner due to complications and 12 million will enter intensive care in the EU and US. This unacceptable situation has the potential to increase Deltex’s revenues 5 fold by 2020 through the development of TruVue. Of the adverse events 51% are directly due to inadequate haemodynamic management. Hemodynamic instability and low blood pressure are frequent, with consequences such as myocardial infarctions, stroke and kidney injury. Complications have serious clinical and financial consequences; unplanned intensive care admissions; longer stay; increased readmissions; increased 30 day mortality; and shorter patient lifespan after discharge. Healthcare faces increasingly complex cases as the population ages and uses ever more complex equipment. Protecting patients from haemodynamic errors through improved monitoring should save thousands of lives, improve outcomes and reduce costs. Diagnostic haemodynamic equipment needs to display the interaction of flow and pressure if it is to be truly effective. Current monitors are failing to meet this need. Deltex and Lariboisiere Hospital Paris have developed the novel TruVue Velocity Pressure Loops system. TruVue provides simultaneous visual display of the patient’s aortic blood flow velocity and aortic blood pressure; and will be a significant contribution to patient safety. TruVue has been CE-marked and is in use at Lariboisiere Hospital. This phase 1 project has two aims: to obtain user input to enhance the Graphical User Interface (GUI); and to cost a multinational multicentre clinical trial for phase 2 application. Deltex envisages that the clinical trial will generate publications, ‘s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Digital Health Hub Europe' (IDH).

assistant: **Concept**

The project objective is to understand the market feasibility of a new, technology enabled healthcare delivery model that is currently being piloted in Birmingham, U.K with encouraging initial results. The project will develop the understanding needed to subsequently pilot this disruptive healthcare innovation in other parts of the U.K. and Europe – essentially providing the market intelligence and understanding to start to take the innovation from ‘niche to mainstream’.The European Digital Health Hub presents a radical new model for delivering healthcare to a growing and ageing healthcare population, who have an increasing number of healthcare needs and long-term conditions. The hub addresses the requirement for providing more efficient care for less money, in response to both economic and healthcare demand challenges.The Hub places the citizen at the centre of the delivery of healthcare through a new, technology enabled healthcare model – delivered in primary, community care, home and mobile settings. It creates an opportunity for radically different models of healthcare to be developed in partnership with local providers across Europe. It disrupts existing healthcare markets by shifting care away from Acute settings, improving services for patients and delivering better services at lower than tariff rates, thereby saving money to commissioners/payers overall whilst delivering integrated, sustainable and citizen-centered care. The specific project outcome, will be a qualified business case with early adoption partners, to undertake a series of delivery pilots in other areas of both the U.K. and Europe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Protecting Personal Data Amidst Big Data Innovation' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The overall goal of PROTECT is to grow a new generation of 14 Early Stage Researchers (ESRs), as PhDs graduated via a unique multidisciplinary, inter-sectoral and international European Training Network ETN).  The network will investigate the protection of rights and interests of individuals and groups impacted by the continuous large-scale analysis of personal data, while still enabling the economy and society to benefit from rapid innovation in digital applications that collect and use this data. The PROTECT ESRs will implement a Personal Career development Plan (PCDP) that will enable them to integrate and apply arguments, analyses and tools from across the fields of law, ethics and knowledge engineering, so that they can take on leading research and data scientist roles within digital services industry and public policy sectors too address challenges of data protection, data ethics and data governance.The rate of technological innovation, now accelerated by big data and machine learning invariably outpaces public policy debate and the development of new regulation for the protection of personal data. This come as the scale and social impact of data analysis is rapidly increasing. Tech companies, especially SMEs, face complex legal and ethical implications resulting from the collection of personal data from users. The pace of change and its complex technical nature serves to overload individuals and enterprises in considering the impact of use of their personal information, especially when this use also delivers attractive personalisation of services. PROTECT ESRs will develop new ways of empowering users of digital services to understand the risks they take with their rights and interests when they go online and offer new ways to enable companies to incorporate priv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Breeding European Legumes for Increased Sustainability'.

assistant: **Innovation**

The aim of BELIS is (i) to increase the competitiveness of the EU and Associated Countries legume breeding industry by improving the methodologies and the governance structures of the breeding sector; (ii) to design conditions that allow an efficient delivery of the achieved genetic progress to the breeders and seed industry, and to the other actors (registration offices, extension services, feed and food industry, farmers). The project will focus on seven forage crops and seven grain crop that are currently grown to produce feed (for ruminants – cattle, sheep, goat and monogastric animals – pig, poultry), food (as is or after processing) or to deliver ecosystem services. BELIS has three main objectives: (1) To develop tools and methodologies for cost-effective breeding programmes and deliver proofs of concept, with and for breeders, (2) To facilitate the economic and regulatory environment: variety registration, variety recommendation and business models, (3) To implement an efficient, ambitious and durable transfer of innovation through the BELIS platform that includes a network of breeders and actors from scientific research, extension services and seed, food and feed industries, as well as a training portfolio. By enabling the creation of improved varieties in many species, adapted to different areas and uses in Europe, this project is relevant for the destinations towards “Biodiversity and Ecosystem Services”, mainly contributing to “Access to a wider range of crops and breeds with a broadened genetic base is improved in line with global biodiversity commitments”. It also supports the “Practices in agriculture and forestry support biodiversity and the provision of other ecosystems services”. In addition, BELIS will have a positive input on natural biodiversity, red
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Task aware location based services for mobile environments', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Despite the growth in the number of mobile users, the wide-spread adoption of ubiquitous wireless networks, and the ever increasing capabilities of mobile handsets, the market of mobile services is still dominated by simple infotainment services. This is especially apparent in the area of Location Based Systems, which with few exceptions (e.g. navigation), have not fulfilled its predicted commercial success in mobile environments. Some reasons here are that (i) content offered in typical LBS applications is still narrow and static (ii) available methods and interfaces in mobile handsets for the discovery of available content are at best insufficient (e.g. keyword type search) and (iii) mobile users still require a GPS module (integrated or autonomous) to utilize location based services and (iv) existing structured content available in several LBS applications is hard to reuse. The scope of the project is to address the above problems to the benefit of the participating SMEs, offering them a clear S&T advantage over their competition, enabling them to deliver commercially successful location based services for mobile environments. TALOS is a project that will provide the technological foundations for the task-aware supply of rich content in mobile LBS environments. In particular, (a) we will develop a user interface based on the principles of task computing, which provides an efficient content discovery channel for mobile users, and (b) we will employ approximate positioning techniques requiring no extra hardware other than their mobile phones. Furthermore, in order to enrich the available content in mobile LBS, we will develop: (c) task annotation tools for structured content, enabling the SMEs to offer their existing content in a task-aware manner, (d) spatiotemporal a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Crystalline Mirror Solutions' (CMS) targeting Seventh Framework.

assistant: **Abstract**

The precise measurement of time and frequency is a critical technology in many different areas from fundamental sciences to sensing and communications applications. This project aims to explore and to secure the innovation potential of a new mirror technology that is targeted to improve on current standards of time- and frequency measurement.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Sustainable production of transgenic strawberry plants. ethnical consequences and potential effect on the producers and consumers.'.

assistant: **Concept**

The rationale for this project is given by the fact that the pharmaceutical industry is currently undergoing a significant change in strategy in preclinical drug development. Relevant advances are being made in the field of genome analysis with the onset of gene chip technologies permitting high throughput investigations and the use of miniature sample quantities. The same is happening for protease analysis and mass- spectrometry. We want to develop the missing link" in high throughput testing: A highly controlled high-throughput bioreactor based on the use of engineered miniature in vitro tissue analogues. This will lead to the establishment of a firm correlation between genome, protease and catalytic expressions or biochemical function resulting in a complementary and more predictive picture of drug action."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Loop spaces and the topology of manifolds' (2002-2006).

assistant: **Innovation**

String Topology is a new field of research which combines several classical techniques of algebraic and geometric topology with the new ideas suggested by quantum field theory and string theory. It was opened to the mathematics community by a pioneering work of Chas and Sullivan in 1999, but it is developing rapidly in a number of directions. We propose an intensive study of this topic addressing the implication of String Topology on the understanding of the topology of the manifolds, with particular emphasis on three-dimensional manifolds. We will also develop the connections with the realm of quantum mathematics and the theory of knots.The methods that will be used in this project will come from many areas of mathematics: from the standards tools of algebraic topology to the more recent techniques inspired by physics such as Feynman diagrams and quantization. The theory of Operads, namely the theory of the algebraic structures of some space, will also have an important role in the project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Microfluidic platform for intra-operative tumor immunohistochemistry' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

We propose to develop an automated microfluidic platform for rapid analysis of the margins of frozen resections of tumors. It will allow cancer cells to be specifically distinguished from healthy cells during the time course of the surgical intervention itself via an immunohistochemistry (IHC) staining protocol completed in 5 minutes. The interest of such platform is that late-positivity, which is defined as the detection of cancer cells within the resection margin of the tumor by means of classical IHC after surgery, can be reduced or even avoided. Patients diagnosed with latepositive margins carry a high risk of cancer recurrence due to possible tumor cells left in the body. Intra-operative margin assessment of tumor resections is already done to evaluate the presence of such remaining cancer cells using different techniques. The most common one is microscopic morphological examination by applying hematoxylin and eosin (H&E) staining on cryo-sectioned surgical specimens, because it can be done easily in a matter of minutes. However, the major drawback of this method is the lack of cancer cell-specific staining: the interpretation relies only on morphology and small numbers of cancer cells infiltrating into healthy tissue are not easily recognizable. We therefore will develop a platform that can perform IHC together with H&E staining on cryo-sectioned samples within 5 minutes. Combining IHC that targets cancer cell-specific proteins with H&E staining will show unequivocally the presence of cancer cells and minimize those variations in the outcome of the analysis that originate from the pathologist’s personal interpretation. It will potentially decrease the recurrence rate, increase the success of post-operative treatment, and reduce unnecessary surgical rescissions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'ICT enabled BEhavioral change ToWards Energy EfficieNt lifestyles'.

assistant: **Innovation**

inBETWEEN goes beyond currently available ICT technologies used for inducing the end User behaviour change towards more energy efficient lifestyles by simultaneously assisting Users to IDENTIFY energy wastes, LEARN how they could conserve energy and MOTIVATE them to act. Apart from detecting energy saving opportunities and offering various incentives for Users’ behaviour change, great part of the motivation aspect will also be associated with the provided ability and means to act through inBETWEEN solution. The overarching technological objective which is to deliver cost-effective solution that brings added value, without significant disruption of everyday activities, through the collaborative inBETWEEN cloud based platform offering advance energy services. It allows Users to integrate their building’s connected devices and systems with advance energy analytics and optimisation services to create a comprehensive recommendation and feed-back solution which will facilitate further the behaviour change towards more energy and cost efficient daily routines. A significant demonstration activity in a range of real life pilot locations in EU with diverse public set-ups, which differ in terms of size, type, climate and patterns of use, will offer the necessary technology validation.