RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Gender Empowerment through Politics In Classrooms' (G-EPIC).

assistant: **Concept**

Ensuring the future of democracy requires empowering all social group to engage, yet the gender gap in political leadership, political ambition and political self-efficacy is the most persistent and most difficult to tackle across Western democracies. The situation when looking across the intersect of gender, social class and ethnicity becomes even more grave. These differences have been shown to begin in the school and classroom dynamics has been cited as the likely socialisation process that leads to these different outcomes.  G-EPIC, a multinational consortium of universities and civil society organisations, has been brought together with the aim of fostering social innovation and testing interventions to reduce gender inequality in politics. The 7 partners in 6 countries (Belgium, Czechia, Denmark, Germany, Spain and United Kingdom) will begin by establishing the state of play through classroom observations and reanalysis of existing quantitative data to understand how inequalities in attitudes and dispositions towards political engagement are learnt. G-EPIC will then create experiments in schools and pilot design-based interventions co-developed with civil-society, teachers and students. These experiments and interventions will be rigorously evaluated in comparisons with control groups and will lead to the development of the Gender Empowerment in Classroom intervention that will be disseminated and delivered in schools across Europe creating the possibility for real change and the reduction of the gender gap in political leadership. In addition, G-EPIC will also carry out a holistic evaluation of the national context and the local and European policy framework to design strategies, regulations and policies that are conducive to a more equitable gender political inv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Ab-initio simulations of nanomaterials' (1994-1998).

assistant: **Concept**

It is the purpose of this project to use ab initio simulation to study the arrangement of the atoms and their motion in clusters structures and relating its properties with the ones of the interfaces and of cluster on surfaces. Ab initio simulations have become possible only in the last few years. Although our investigation is primarly motivated by a basic interest in atomic level processes, the systems and mechanism we propose to study are relevant to the new material industry. The atomic arrangement and electronic structure of clusters will be studied. Of particular interest will be the structure and the degree of mixing of materials in the clusters. Semiconductor-semiconductor and metal semicon- ductor materials form one set for study. A second area is the deposition of clusters on surfaces. In addition to investigating particular material problems, the project also aims accelerating the entry of Spanish material research into the rapidly expanding field of ab initio simulations.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Bioactivated hierarchical hydrogels as zonal implants for articular cartilage regeneration' (HYDROZONES).

assistant: **Concept**

Degeneration of cartilage is a major cause of chronic pain, lost mobility and reduced quality of life for millions of European citizens. From a clinical point of view treatment to achieve cartilage regeneration (hyaline) and not only repair (fibrous) remains a great challenge. No clinical therapy is available that leads to healing of cartilage defects.Current cartilage implants cannot establish the hierarchical tissue organisation that appears critical for normal cartilage function. We hypothesise that a biomimetic zonal organisation is critical for implants to achieve cartilage regeneration.HydroZONES represents an interdisciplinary consortium that adopts a strategy to regenerate, rather than repair, articular cartilage based on the tissues zonal structure and function.HydroZONES will use advanced bioprinting technology for fabrication of 3D biofunctional hydrogel constructs, eventually mechanically reinforced by degradable polymer scaffolds, as biomimetic reconstitution of the zonal organisation of natural cartilage. Constructs will be optimized for cell-free application and also for combination with chrondrogenic cells (chondrocytes and/or MSC). Stringent in vitro and long term in vivo testing of the constructs will be employed that will yield a new clinical standard for pre-clinical testing.Cutting edge 3D tissue models and bioreactor technology will be used together with in silico modelling to develop a predictive in vitro assay and test system that will be validated against the in vivo data.Installation of a quality and regulatory affair management system, GMP production, accredited in vitro testing and involvement of clinical partners and companies with experience in clinical trials ensures that the best performing construct will be brought into an optimal positi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Architecting More Than Moore – Wireless Plasticity for Heterogeneous Massive Computer Architectures' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The main design principles in computer architecture have shifted from a monolithic scaling-driven approach towards an emergence of heterogeneous architectures that tightly co-integrate multiple specialized computing and memory units. This is motivated by the urgent need of very high parallelism and by energy constraints. This heterogeneous hardware specialization requires interconnection mechanisms that integrate the architecture. State-of-the-art approaches are 3D stacking and 2.D architectures complemented with a Network-on-Chip (NoC) to interconnect the components. However, such interconnects are fundamentally monolithic and rigid, and are unable to provide the efficiency and architectural flexibility required by current and future key ICT applications. The main challenge is to introduce diversification and specialization in heterogeneous processor architectures while ensuring their generality and scalability.In order to achieve this, the WiPLASH project aims to pioneer an on-chip wireless communication plane able to provide architectural plasticity, reconfigurability and adaptation to the application requirements with near-ASIC efficiency but without any loss of generality. For this, the WiPLASH consortium will provide solid experimental foundations of the key enablers of on-chip wireless communication at the functional unit level as well as their technological and architectural integration. The main goals are: (i) prototype a miniaturized and tunable graphene antenna in the terahertz band, (ii) co-integrate graphene RF components with submillimeter-wave transceivers and (iii) demonstrate low-power reconfigurable wireless chip-scale networks. The culminating goal is to demonstrate that the wireless plane offers the plasticity required by future computing platforms b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Israel Night of Science' (ISRANOS), addressing dissemination and exploitation.

assistant: **Impact**

Whoever studies science and does not use it for the benefit of others is like a farmer who ploughs a field without sowing it.                                                                                                         (Tolstoy)  The proposed project intends to provide an opportunity for lively, informal interchange, between scientists/researchers and the general public of all ages in Israel.  We wish to present, through a diverse range of activities, opportunities for researchers and scientists to engage in a meaningful dialogue with the general public so that we can begin to demythologize the perceived image of scientist/researcher as inaccessible, remote and aloof. By changing this image we can erode public mistrust of science and the unwillingness of young people to purse a career in research.  Employing imaginative and vibrant interactive activities we will further enhance and strengthen the rich cultural heritage of science in Israel and the European Union; promote science literacy among Israelis of all ages; and encourage youngsters to pursue science studies towards a career in science and technology.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Short and long term effects of genetic immunization on the fish immune system' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

Using the rainbow trout (RBT) and viral haemorrhagic septicaemia virus ( VHSV) genes as a model of immunization, the aims of the present project are i) to analyse the effects of a long lasting antigen production on the specific and non specific immune response, ii) to analyse the effect of the continuous delivery of the antigen on the shape of the B and T cell repertoires, iii) to evaluate the modulating potential of selected cytokine or virus-induced genes on the immune response to genetic immunizationNucleic acid immunization can induce antibodies, cytotoxic T lymphocytes (CTL) and protection against many pathogens. The underlying mechanisms remain obscure and must be understood to permit rational manipulation and optimisation of the methodology.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'REVOLUTIONIZING DFU TREATMENT: ESCHAREX - A GAME-CHANGING SOLUTION' to be submitted under Horizon Europe.

assistant: **Abstract**

INTRODUCTION: MediWound develops wound care solutions, for chronic wounds and severe burns. The Company’s leading drug candidate under development and the subject of this EIC Accelerator project is EscharEx®, a groundbreaking bioactive therapy specifically targeting the debridement of Diabetic Foot Ulcers (DFUs) and other challenging chronic wounds. EscharEx is poised to revolutionize the standard of care (SOC) that for many patients is ineffective. EscharEx - A GAME-CHANGER IN CHRONIC WOUND CARE: EscharEx is a complex mixture of proteolytic enzymes, primarily bromelain, designed to selectively remove necrotic tissue and biofilm from chronic wounds. This process is highly efficient and does not harm viable tissue, providing an optimal wound bed for healing. Unlike traditional knife-based debridement, which can be traumatic and painful, EscharEx offers a non-surgical alternative that is swift, safe and effective. This aspect is especially critical for diabetic patients, often elderly and suffering from co-morbidities, who may find surgical options less suitable. The currently available non-surgical options are notoriously slow and ineffective, causing delays to the wound healing process, and resulting in significant incremental costs and poorer overall outcomes. CLINICAL PROGRESS AND VALIDATION: MediWound's confidence in EscharEx stems from the outcomes of three Phase 2 clinical studies. These studies demonstrated the therapy's rapid, safe, and effective debridement of DFUs and Venous Leg Ulcers (VLUs). Additionally, EscharEx shares the same active pharmaceutical ingredient as NexoBrid, MediWound's EMA and FDA-approved drug product for debridement of severe burn wounds. The consistency of active ingredients and similarity of indications between these two drugs provides a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Central European Aeronautical Research Network Events' (CEARES-NET), addressing dissemination and exploitation.

assistant: **Impact**

The main aim of the project is to help to enable the Central European aeronautical research establishments, universities and companies to cooperate with each other and to integrate more to the European research arena. This objective will be achieved via two workshops held in Central Europe to enable many local experts to participate.The organisers will rely on the CEARES Network, set up during the CEARES Project (FP7 1st of April 2008 till 31st of March 2010).The timing of the two workshops foreseen for the project will be related to the upcoming aeronautical calls of the European Commission. The first one, planned to be organised in Vienna will precede the 4th AAT call, while the second one, which would take place in Warsaw will be related to the 5th AAT call. Both workshops will address more topics besides the FP AAT calls, for example Clean Sky, SESAR, Marie Curie actions, EUREKA, infrastructural funds and bilateral co-operations.The organisers will take the advantage of the contact data base of the former CEARES project and expect a wide interest for the workshops. The outcome of the project will be new co-operations within the region and also between Central Europe and other European regions. The events will facilitate research co-operations in general, common project proposals with increased Central and Eastern European participation for the upcoming calls and other research programmes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Smart Household Waste Management' (SmartDtd).

assistant: **Concept**

EU Waste Framework Directive targets recycling rates of 50% by 2020 for municipal waste. To reach this goal new waste management strategies need to be applied by municipalities, not only to align with EU recycling targets but also to be able to cover increasing disposal costs. Strategies should begin by making households aware of the necessity to lower their waste generation, while increasing their recycling rate. One of the most effective ways to motivate households, is through ""Pay as you throw"" (PAYT) schemes, based on the implementation of a disposal fee per household, according to the amount of waste generated. In order to be able to apply PAYT schemes, selective waste collection needs to be implemented by municipalities or waste management companies. One of the most common, is door-to-door (DtD) waste collection, as it greatly facilitates the application of PAYT schemes while promoting recycling among households. Even though, the combination of DtD collection with PAYT greatly reduces the load of waste generated, current systems to account for the amounf of waste generated per household are not accurate. They quantify based on the number of bags/bins (with a set volume) each household generates, without considering that in many occasions these bags/bins are just partially filled upon collection. Nevertheless, households are charged the same, neglecting if all the volume has been filled. A new accurate measuring system is needed. We are Distromel, a spanish company specialized in the develoment of technological solutions for the waste management market. Aiming to solve an increasing concurrent demand from private and public WM companies, we have created SmartDtD: a certified weighing and identification system (RFID number) integrated in a container that can be em
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Rheumatoid Arthritis Caught Early: investigating biological mechanisms preceding chronification of joint inflammation to identify patients prior to presentation of classic chronic arthritis' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Rheumatoid Arthritis (RA) causes long lasting disability. At the time of clinically evident arthritis and diagnosis, the disease is already persisting, requiring long-term suppressive treatment. My overarching aim is to prevent chronic arthritis and RA by inhibiting the evolving auto-immune response in a pre-arthritis phase. Currently, identification of RA-patients before the classic presentation with clinically evident chronic arthritis is beyond the state of the art. I here aim to achieve this early recognition by increasing the mechanistic understanding of pre-arthritis phases. I intend to study RA-specific auto-immune responses at the cellular and humoral level as well as markers reflecting local and systemic inflammation. These aspects are selected based on my world-wide validated rule to predict RA-development in early arthritis and on recent work on progression from Clinically Suspect Arthralgia (CSA) to clinical arthritis.This project is now finally feasible, thanks to unique ‘pre-RA’ cohorts and cross-boundary preparatory work done with basic scientists, clinicians and engineers. My research concept is to integrate the products of separate trajectories in a longitudinal study and translate it to the clinic. Patients with CSA will be studied serially in time. Using validated methods and novel techniques and insights we will: delineate molecular and predictive features of RA-specific auto-antibodies and auto-antibody secreting B-cells, identify improved markers of systemic inflammation and test and validate a computer-aided image analysis system to detect subclinical joint inflammation on MRI. Serial data will be combined to reveal interactions between markers and time relationships. Lastly a prediction model identifying imminent RA will be developed. The forefro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'RAMAN spectroscopy for identification of aerospace composites' (RASAC) under Seventh Framework.

assistant: **Objectives**

In the coming decades throusands of aircraft are due to be retired and dismantled. Other than components to be re-used, substantial parts of aircraft are stripped and shredded. Whereas today's technologies such as XRF work well in many respects, XRF is unable to properly identify aircraft composites, penetrate coatings and XRF is also costly.This proposal will modify and refine RAMAN spectroscopy devices to demonstrate their capability to robustly identify aerospace composites, also when subject to ageing and coating.RAMAN is a well-established spectroscopy technique outside the aerospace domain. It works by shining a laser beam on a sample, and identifying the molecular vibration response.TNO has access to a handful of different RAMAN devices to perform the feasibility study. To enforce industrial, economic and operational realism, we are bringing companies AELS and Avantes as subcontractors. Both are very active and well-established in European recycling networks. TNO also brings a relevant industrial network to support further industrial development of a portable RAMAN device.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Development of an effective RNA interference-based anti-HIV-1 therapy using an SV40-derived gene transfer vector'.

assistant: **Innovation**

The acquired immunodeficiency syndrome (AIDS) caused by infections with the human immunodeficiency virus type 1 (HIV-1) has become a pandemic continuing to grow at an alarming rate, despite the availability of highly active anti-retroviral chemotherapy (HAART). We here propose to develop a novel therapy for the treatment of individuals infected with HIV-1. This therapy involves the application of RNA interference (RNAi) to prevent productive infection of new cells with HIV-1 and so eventually cure infection. So far, RNAi-based inhibition of HIV-1 replication has been accomplished by introduction of virus-specific synthetic short double-stranded RNAs referred to as short interfering RNAs or DNA constructs encoding short hairpin RNAs. However, their use as therapeutic antiviral against HIV-1 is limited because of the rapid emergence of viral escape variants.