RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Development of Functionalised Cell Seeded Bioartificial Organ for Transplantation in Nerve Repair', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Injuries and degenerative diseases of the central nervous system constitute a bottleneck in medical and surgical practice for which no therapy currently exists. To ensure clinical translation, NeuroGraft is organised in three R&D Work-Packages. NeuroGraft will develop functionalised cell seeded bioartificial organs, specifically spinal cord conduits for transplantation, incorporating a potent immunomodulatory cytokine (IL37) to target the initial inflammatory response to increase the survival and therapeutic efficacy of transplanted mesenchymal cells and the expression of potent neuro-regulatory molecules for enhanced functional nerve regeneration in the central nervous system.This exciting concept will be realised through the NeuroGraft consortium, consisting of one academic and four industrial partners (all SMEs), across four countries, with distinct synergistic expertise (including regulatory expertise) to develop cell seeded functionalised bioartificial organs as valuable solutions towards spinal cord repair. Regulatory advice is incorporated at an early stage in the development cycle, to facilitate the translation of the novel bioartificial devices developed, to the market in as short a timeframe as possible. The NeuroGraft consortium will validate the safety, efficacy and biodistribution of the functionalised bioartificial organs developed in a pre-clinical model of spinal cord under GLP conditions. Full Quality Assurance reports will be completed towards CE Mark regulatory approval of the medical device for spinal cord repair. These studies will facilitate progression to clinical trials of the technology (post project) and the development of a marketable product within 6 years of the completion of the NeuroGraft project. Intellectual property will be patented ens
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'A Theory of Religious Organizations' (RELIGION).

assistant: **Concept**

In this research project I am proposing a novel theoretical framework to explain religious organizations. I incorporate the notion of religious beliefs in a rational framework of social interaction. This will allow me to distinguish this theory of religious organizations from both existing work on religion and from theories of other social organizations. Moreover, it will allow me to analyze the dynamic evolution of religious organizations. The analysis of religion from an economic agent point of view will create new horizons by adding to the rich literature stemming from other social science disciplines and evolutionary biology. The objectives of this research project are: (i) To provide an applicable model of religion that will link the individual and social aspects of religion; (ii) To provide a theoretical framework to understand the relations between different religious groups and between religious and secular groups; (iii) To understand the dynamic evolution of religious beliefs and religious organizations; (iv) To understand the connection between religious leadership and political power; (v) To provide a basis for future empirical work by yielding new testable predictions about the dynamics of religious organizations and religious tolerance.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Job Mobilities and Family Lives in Europe Modern Mobile Living and its Relation to Quality of Life' (2002-2006).

assistant: **Innovation**

The considerable rate of global social, economic, political, and demographic changes leads to increasing demands on mobility and flexibility of persons and institutions. As a consequence, new patterns of contingency and constancy, movement and integration, work and family are emerging. An extended mobility of employees is both a requirement and a precondition of the knowledge-based society and essential for social and territorial cohesion in Europe.One of the key challenges Europe faces in this situation is to understand how to encourage the flow of people and ideas across Europe without creating impairments regarding family formation, social integration, and individual well being. To improve this understanding is the main objective of this comparative research, covering six comprehensively selected European countries: both old and new EU members, and an associated country, representing varying levels of economic development, demographic situation, social environments, and cultural traditions.The study is targeted at:- mapping the demands and potentials of job mobility across selected regions, and identifying the barriers and triggers influencing the readiness to become mobile- identifying the consequences of job mobility for family formation (marriage, fertility, divorce), family relations (child care, coping, conflict management, division of labour), social integration, and individual well being- assessing the gender-specific issues in the field of mobility with a special focus on women, as our previous research suggests the costs of job mobility are higher for women- developing suggestions for adequate political measures to advance quality of life of mobile employees and their families in Europe, and balancing demands against readiness to move.The theoretical concept
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Vision-based Inspection Systems for automated Testing of Aircraft interiors' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The VISTA project aims to post-assembly testing of aircraft interior installations in both cabin and cargo units in order to ensure quality and reliability of located components. This goal will be pursued by the development and implementation of a multi-sensor platform and sensor processing algorithms, integrating on-board a mobile system and an interface for data transmission, able to provide efficient automated testing and quality reports. In detail, multiple optical devices, including 3D LIDAR, omnidirectional laser profilometers, RGB-D, and (stereo) vision sensors, integrated with on-board image processing hardware, will be tested for the 3D modelling of the aircraft interior. In addition, the sensor suite will include line scan cameras for colour inspection of surface quality. All sensors will be integrated on an automated guided vehicle (AGV) that will collect and store sensor measurements, while traversing both cabin and cargo areas. The collection of full 3D models, i.e. 3D models augmented with metadata, such as colour, material and texture, will feed high-level algorithms that will automatically determine tolerances of the components with respect to positioning, gap and flush, and assess surface quality in terms of texture, colour, and defects. An interface for data transmission will be developed and tested for visualization and documentation, which will be made available to the human operators via suitable interfaces based on Augmented Reality (AR).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Frugal Zero-Emission Vehicles for the Urban Passenger challenge'.

assistant: **Objectives**

While Fully electric vehicles (EV) have zero tailpipe emissions and are seen as a key solution to meeting the European Fit-for-55 target of reducing CO2 levels in 2030 and climate-neutrality by 2050, much more can be potentially achieved if the global market uptake of innovative EVs is accelerated. The ZEV-UP project aims to address this urgent need by developing modular, cost-effective, and user-centric EVs for both passenger and goods transportation. Leveraging innovative design and engineering techniques, ZEV-UP vehicles will be tailored to meet the specific needs of users in both developed and emerging markets, ensuring high levels of user acceptance and market uptake. Key innovations include a base L7e BEV model that is designed respectful of affordability and can be upgraded and adapted for various purposes and needs, including commercial applications and higher-value passenger vehicles. By optimizing vehicle components for reduced material usage and enhanced structural properties, the project will achieve lighter vehicles with increased autonomy and minimized environmental impact. ZEV-UP will also develop digital-twin models to improve vehicle development efficiency and reduce validation costs, as well as designing charging capabilities compatible with a variety of regional power systems. Novel business and usage models, such as Battery as a Service, will be explored to maximize the benefits and impact of the L7e BEV platform. User-centric design, informed by market research and field interviews in both established and developing countries, will be a central focus of the project. Additionally, ZEV-UP will develop a proliferation model to assess policy intervention scenarios and strategize for short- and long-term BEV uptake in various markets. By delivering these
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Novel dry air switchgear technology to reduce industry’s dependence on SF6'.

assistant: **Concept**

Nuventura develops medium voltage (MV) gas insulated switchgear (GIS) which replaces SF6 - the world's strongest greenhouse gas - with dry air. Annual SF6 emissions are 8,100 t, equal to the CO2 emissions by 100m cars. 85% of SF6 gas is used as a GIS insulating medium. Though recycling of SF6 is possible, it is usually not done due to difficulty & cost. It can be expected that SF6 that exists now & that is produced in the future will persist for thousands of years, whether in GIS equipment or, ultimately, in the atmosphere. SF6' atmospheric lifetime is 3,200 years. MV power grids (12-40.5 kV) use 3 types of switchgear: air insulated switchgear (AIS), solid insulated switchgear (SIS) & gas insulated switchgear (GIS). AIS have a large physical footprint, costly maintenance, & inability to meet the demands of urban grids. SIS works only in rare & highly specialized use cases. Nuventura combines the advantages of GIS & AIS in a new dry air switchgear that is sustainable, safe & reliable.


**Keywords:** greenhouse gas,electrical industry,alternative technology,climate change mitigation,global warming potential,industry 4.0
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Paleodietary analyses of the first Andean cities: high-resolution assessment to macronutrients using a multiproxy approach.' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Paleodietary analyses of the first Andean cities: high-resolution assessment to macronutrients using a multiproxy approach.The socio-ecological circumstances that underpinned the rise of the earliest urban centers in the Americas are some of the most intriguing and unclear aspects of New World archaeology. In particular, the emergence of Andean cities 5000 years ago has been the subject of contentious debates. On one hand, the Maritime Foundations of Andean Civilization have challenged the conventional assumption that agriculture was a pre-condition for early city development, and on the other, recent archaeological investigations have reenergized these debates by demonstrating that plant management and agriculture were developed in the region before the rise of complex societies and urban centers. Uncertainties remain regarding the proportional contributions of plants, fish and terrestrial animals to individual diet, and their potential roles in sustaining early sedentary and stratified urban populations engaged in monumental architecture. PACHAMAMA will employ a suite of molecular techniques to unlock the relationship between diet and processes of social complexity among early urban groups in coastal Peru. Using a multiproxy approach that integrates stable isotopes of bone collagen (bulk and single amino acids), Bayesian mixing models, and palaeoproteomic analyses of dental calculus, the fellow will address the role of marine resources and plant production systems in Formative period (3000 - 1 BC) populations on the North-Central coast of the Central Andes, a region known as ""the crucible of Andean Civilization."" This novel integrative approach will advance the state-of-the-art on social complexity and urban development in hyper-arid regions of the ancient world.  "
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Endothelial-microglial communication as a sculptor of brain capillary network architecture' (AngioArchitects) under Horizon Europe.

assistant: **Objectives**

Brain capillaries are the lifelines of the brain, supplying essential nutrients and oxygen and safeguarding its delicate environment. Therefore, proper establishment of this hierarchically branched circuitry is crucial for brain growth and function throughout life. Orchestrating the creation of a functional vascular network requires coordinated signalling among endothelial cells, the vessels´ building blocks, with adjacent cells. Despite its importance, the exact spatiotemporal events, and molecular bases of the capillary network construction during postnatal development remain a mystery. Elucidating this dynamic process within the intact developing mammalian brain in both space and time is a challenging but a necessary step to unveil this fascinating biological knowledge gap. Towards this goal, I recently established a longitudinal live imaging approach to capture brain development processes with minimal perturbation. Based on preliminary work, I postulate that endothelial tip cells instruct microglia, the brain resident immune cells, to serve as pathfinders and guide them to their target vessel. To address this original and innovative hypothesis, ANGIOARCHITECTS proposes to employ a powerful multi-disciplinary combination of mouse genetics, two-photon live imaging, omics profiling, high-resolution microscopy mapping, and computational modelling tools to reveal the developmental principles of building the capillary network, focusing on communications between endothelial tip cells and microglia. This pioneering project will be the first to offer unprecedented imaging of vascular-immune interactions during angioarchitecture formation in the neonatal period, when the brain is highly susceptible to insults and injuries. ANGIOARCHITECTS will not only advance the frontiers o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project '‘The re-privatization of the contemporary art world: private collectors and artist-entrepreneurs in the changing geographies of European art’' (2014-2020).

assistant: **Concept**

This project examines the idea that there is an on-going re-privatization of the European art world, in which increasingly it is private art collectors and communities of artist-entrepreneurs that are creating commercial value in the contemporary art market and redrawing our cultural landscape. The rapid expansion of the global art market has meant that art has entered a period of radical institutional, market and industry transformation. Private art collectors and artist-entrepreneurs are now competing with public institutions and the locus of power is moving from public to private actors. This change calls for new critical investigations of agency, value creation and creativity of the art world. My work addresses an area of activity that is central to both European cultural and economic development. The thriving European art scene is a key field within the creative and cultural industries identified as central to Europe’s development and integration by both the Creative Europe strategy and the Europe 2020 strategy. With new and innovative empirical research, a program of training and knowledge transfer, and an ambitious dissemination plan I aim to contribute to important non-academic and academic debates over the geography and practice of the art world, by exploring how this re-balancing is changing how and where agency and value creation now takes place. Building on geographical analysis and ethnographies of London and Stockholm based private art market actors, I aim to develop new theoretical insights into: a) how and where arts´ commercial value gets created; and b) the increased presence of entrepreneurial and private actors´ strategies in the art world. This proposal involves the training and development of an experienced researcher through: i) time spent in one
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Effect of network of different grain boundaries and triple junctions on sensitivity of microstructures to hydrogen embrittlement' (HySens).

assistant: **Concept**

A network of grain boundaries (GBs) and a microstructure which is less sensitive to hydrogen embrittlement using grain boundary engineering will be assessed on multiple scales. The fabrication of bi and tri crystals with a great variability of grains misorientations according to the probability of their presence polycrystalline nickel and nickel-based superalloys will be done. The hydrogen-GBs and hydrogen- triple junctions (TJs) interactions will be examined for different configurations of nickel bi-crystal and tri-crystals systems having variety of grain boundary energy, vacancy concentration and excess volume. Finally, influence of hydrogen on GBs and TJs will be characterized by diffusivity, trapping or segregation energies and cohesive energies. The atomistic level investigation will be done to understand the fundamentals of hydrogen embrittlement of GBs and TJs having same orientation as of fabricated crystals. The bi- and tri-crystals will be modelled in Molecular Dynamics code using LAMMPS software for understanding at atomistic level. A 3D polycrystalline FEM model will be reconstructed and these simulations should provide the optimum solutions for the architecture of the GBs and TJs networks to obtain the less sensitive microstructures to hydrogen embrittlement.


**Keywords:** Hydrogen Embrittlement, Grain boundary engineering, Diffusion, Crystal growth, Triple junction, Molecular dynamics, FEM
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Metabolic control of immune cell function during fungal infection'.

assistant: **Concept**

The high mortality rates and healthcare costs associated with severe fungal infections highlight the urgent need to unveil their pathogenetic mechanisms and develop more effective diagnosis and treatment measures. Innate immunity has a key role in host response to fungal infection, by mediating fungal recognition and elimination, and modulating adaptive immune responses. The long pentraxin PTX3 is a soluble pattern recognition receptor that is involved in the recognition and opsonisation of Aspergillus fumigatus. Metabolism is a central regulator of immune cell function. Phagocytosis of A. fumigatus conidia elicits enhanced glycolysis in macrophages and is essential for optimal antifungal effector functions. Preliminary data from the host lab indicate that PTX3 deficiency, by compromising the metabolic reprogramming of macrophages, impairs phagocytosis, but also their conidiacidal capacity upon infection. Nevertheless, little is known about the mechanistic bases linking the functional activity of PTX3 and immune cell metabolism in the pathogenesis of fungal infection. In METAFUN, we propose to (i) define the molecular and cellular mechanisms whereby PTX3 regulates immune cell metabolism, (ii) dissect the spatiotemporal contribution of PTX3 to intracellular mechanisms of fungal clearance, and (iii) evaluate the contribution of PTX3 to fungicidal mechanisms in a human disease-relevant context using lung-on-a-chip systems. This original and interdisciplinary project will reveal previously unanticipated functions of PTX3 in antifungal immunity and will lay the foundations for the identification of new diagnostic and therapeutic targets for fungal disease.


**Keywords:** pentraxin 3, macrophages, Aspergillus fumigatus, lung-on-a-chip, immunometabolism, immunogenetics