RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Role of canonical Wnt signaling during somite formation in the zebrafish embryo'.

assistant: **Objectives**

Segmental elements of the vertebrate body plan, such as vertebrae, ribs and most skeletal muscles, derive from embryonic somites. Somitogenesis is a spatially periodic process that is prefigured in the presomitic mesoderm (PSM) by coordinated oscillations of gene expression that set the rhythm of the “segmentation clock”. The position in the PSM where these oscillations arrest is termed the determination front and is the site where segment boundary is positioned. Although the Delta/Notch pathway has recently been shown to synchronize oscillating cells, little is known about the molecular mechanisms that define the determination front and link it to the segmentation clock. The Wnt pathway has been hypothesized to provide such a link in mouse and chick, but its early effects on mesoderm specification and tail formation have made studying its role in later somite patterning difficult. Here we propose to investigate the role of Wnt signaling during somitogenesis in the zebrafish embryo, which offers unique accessibility to both genetics and imaging. In order to uncouple Wnt function in early mesoderm specification and somite patterning, we will use inducible transgenic zebrafish lines to transiently modulate Wnt signaling later in development. Our preliminary results clearly show that this transient disruption of Wnt specifically affects somite patterning. Thus we will combine this method with analysis of determination markers, boundary formation and oscillating gene expression to further explore the role of Wnt. We will also use a new quantitative time-lapse method to measure potential changes in oscillator period. Finally, we will test genetic interactions between Wnt and the Notch pathway by using mutant lines available in the Oates lab. Our project will thus take advant
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Provision of services for enhancing innovation management capacity of the Cypriot SMEs by the Enterprise Europe Network Cyprus' (KAM2CY5) targeting Horizon 2020.

assistant: **Abstract**

The project envisages the continuation of the provision of high quality innovation management capacity assessment and support services to SMEs in Cyprus aiming at the enhancement of their competitiveness, smart growth and profitability. Moreover, the project aims at creating a better understanding of the fundamental principles of innovation management and their better integration in the value chain of local SMEs. The services will be provided by the Research and Innovation Foundation (RIF), coordinator of the Enterprise Europe Network Cyprus (EEN-Cy) and will be integrated by EEN-Cy services. RIF provides relevant services since 2014 through preceding EU funded projects (KAM2CY1- ΚΑΜ2CΥ4). The project targets two groups of SMEs with a separate services package provided to each group, as described below: (a) Key Account Management (KAM) services to SME-beneficiaries of EIC pilot and its successor in Horizon Europe.The procedure for the provision of KAM services includes the following steps:-identification of weaknesses in innovation capacities of the SMEs; -identification and selection of suitable coaches to address the identified weaknesses; -moderation of the coach-client relationship; -in the case of SME Instrument beneficiaries, accompany the SMEs throughout the implementation of their projects. (b) Services for Enhancing Innovation Management Capacity (EIMC) to promising SMEs with potential for growth via innovation. The EIMC service package includes: -a diagnostic audit / assessment of the SME innovation management; -a root/ cause analysis of the results;-development of a tailor-made action plan; -assistance of the SME in action plan implementation and monitoring. The project foresees the provision of 5 KAM and 12 EIMC service packages. The average duration of each
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Systems Biology of Cancer Kinome' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Protein kinases mediate most of the signal transduction events in cells by phosphorylation of specific substrates – modifying their activity, cellular location, and/or association with other proteins. The extremely critical role of kinases for critical cellular decisions came evident when an unexpectedly large number of kinases (120/518) were found to be mutationally activated activated or their expression increased due to gene-amplification or translocation in many types of human cancer, suggesting that either a large number of kinase-pathways can contribute to cancer, or that many kinases can regulate the same pathways when activated unphysiologically. These observations point towards a model where cancer can be caused by combinations of multiple different alterations within the cellular systems that control cell and tissue growth, and cancer can thus be clearly described as a complex and multifactorial disease. To date, cancer causing mechanism have been primarily studied using the methods of cell biology, biochemistry and/or genetics, methods which typically reduce complex cellular responses into (often linear) sequences of signaling events. While these efforts have accumulated enormous amounts of detailed information, the heterogeneity of the experimental approaches makes integration of this information into a comprehensive quantitative model a daunting if not impossible task. The critical information about the connectivity of concurrently active signaling pathways, their dynamics and the emergence of physiological responses from molecular events has remained elusive. The main goal of this proposed project is to use systems biology methods to characterize and decipher the cancer linked kinase signalling networks at a molecular and quantitative level to provide the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Promotion of Competence to Up-grade the RTD Potential  in Science and Technology' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Research in the Scientific and Technological Development in Electrical Engineering is a strategically vital component of a competitive economy. Attaining expertise right across of this huge and multidisciplinary field, demands a high level of research potential. PROCUST`s aim is to provide an international independent expert evaluation of the existing research quality level and infrastructures of ICPE-CA, identifying the gaps and opportunities and to define an Action Plan to up-grade and reinforce its RTD potential. This project will be a complement of actions generated in FP6 SSA – INDUMAT and other national projects for improving the research capacity of ICPE-CA in order to assure a better participation as valuable partner in EU research initiatives and to increase the economic cohesion. PROCUST has the following objectives: - to analyze the state-of-art of the institute; - to realize SWOT analysis which will contain the strengths, weakness, opportunities and threats; - to provide an Action Plan to up-grade and reinforce the RTD capacity of the institute. Accomplishing of PROCUST`s objectives will provide ICPE-CA the possibility to enrich its capacity to play an important role in bridging the gap between science, economy and policy in Romania and Europe in a knowledge based society,  in order to fully realise the European Research Area in the enlarged Union, using the principle “learn from nature”.  By the transposing in reality of the Action Plan resulted from PROCUST, ICPE-CA will fructify its improved effectiveness and gained advantages directly in the benefits of SME`s and industrial organizations, in future European and national partnerships in research projects.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'MEDUSA, a Meteorological Decision Support System for Aviation' (MEDUSA).

assistant: **Innovation**

Weather contributes both directly and indirectly to incidents, accidents, and delays in air traffic and hence derogates safety and efficiency of airport operations. Today, the aviation stakeholders receive their meteorological information from different sources, at different update rates and with different levels of resolution and accuracy, often leading to misunderstandings and even wrong decisions. The goal of the project is to develop a MEteorological Decision sUpport System for Aviation (MEDUSA) to provide adequate information about adverse weather situations to all decision makers in the airport environment such as airports, air navigation safety providers, airlines, and weather services. MEDUSA is a highly interdisciplinary and intersectorial project dedicated to the scientific and technological development of an end-user oriented application in the field of aviation meteorology including a marketing and commercialization strategy. MEDUSA, combining scientific complexity with high requirements on technical robustness, will provide an integrated weather information solution to aviation. Adverse summer weather like thunderstorms and heavy precipitation), and adverse winter weather situations like heavy snow fall, icing and freezing conditions at the airport will be considered. Key for the technical development is the integration of the various meteorological products in a robust, reliable, and real-time operational system with an easy-to-understand visualization to assist end-users in daily decision making. The project is organized in four phases, (i) test of existing algorithms and forecasting modules and selection of best suited algorithms and modules; (ii) development of joint platform MEDUSA; (iii) implementation and test of MEDUSA at the airports Munich, Frankf
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Rapid production of tooling' (RPTOOL) under Fourth Framework.

assistant: **Objectives**

Rapid Manufacturing and Tooling is a fast growing area of development which has received considerable attention from various sectors of the industry over the past few years and is considered a key technology for the future. This is because of the great benefits that could be obtained through utilising Layer Manufacturing Technologies (LMTs), such as significant reduction in lead-time (up to 80%) and production costs (up to 50%). The main objectives of the project are: - to propose methods for optimising tool design and increasing the durability of tools through the application of engineering analysis and simulation. - to analyse and model the geometrical accuracy and surface roughness of tools fabricated by Stereolithography (SLA) and Selective Laser Sintering (SLS). - to investigate fabrication and post processing methods for direct production of tools. - to develop automated finishing processes for tools produced with LMTs and investigate their technological capabilities. - to identify the constraints of SLA and SLS technologies for rapid tool production in terms of part complexity, tool accuracy, durability and possible application areas. - to provide guidelines for better utilisation of LMTs for direct fabrication of tools. The main innovative aspects of this proposal include: - Development of a Concurrent Engineering (CE) approach for integration of part and tool design taking into account the specific characteristics of LMTs. - Investigation of dimensional accuracy and surface roughness of tools fabricated by SLA and SLS. - Improvement of the existing processes for direct production of tools with LMTs. - Development of automated finishing methods for tools produced with LMTs and investigation of their technological capabilities. - Systematisation of the acquired k
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'TRANSMODEL BASED INTEGRATION OF TRANSPORT APPLICATIONS AND NORMALISATION' under Fourth Framework.

assistant: **Concept**

TITAN concerns the validation and further development of Transmodel, an already established EU reference data model for public transport operators. The core of Transmodel will be validated and amended in the light of full-scale pilot trials, and extended to fresh operations in the public transport sector in the framework of TITAN/1. The content of the model will also be enlarged, and widely disseminated throughout the sector in Europe. Standardisation will be supported through certification procedures geared to adoption by the European Committee for Standardization, in the framework of TITAN/2 as an accompanying measure.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Identification of species in processed seafood products using DNA based diagnostic techniques.'.

assistant: **Objectives**

Fishery products comprise a wide variety of species and products from which is difficult to know the composition, especially in the case of thermally processed seafood products. Identification of fish species in these products, by specific protein profiles, could be hindered by the denaturation of these proteins caused by the severe thermal treatment used during the elaboration of these products. The use of DNA analysis as a tool for species identification has shown to be successful for identifying canned tuna species (AIR2 CT94-1126). The use of DNA diagnostic techniques for different groups of products could be of value since in some cases there is not a reliable method of identification, such in sterilised products.In other cases the presence of several sources of fish can impede the identification. It is thought that DNA analysis techniques could solve several authentication problems up to now unresolved.The work program in this project will involve the study of the following type of products:a. Sterilised products Canned fish and mollusc Baby Food Fish Pateb. Heated Products Smoked Fish Fish meal Pre-cooked Fish and molluscc. Non-heated Products CaviarThis study will comprise several steps needed for the determination of the best methodology to be applied in each case:1. Collection, authentication and preparation of products.2. Developing of DNA isolation methods suited to each product.3. Cytochrome b and Control region DNA sequencing in species of interest.4. Designing of primers for the obtaining of DNA fragments from the products.5. Development of secondary DNA- diagnostic methods based on analysis of PCR amplicons.6. Validation of the diagnostic methods.7. Creation of a database for fish species identification accessible via Internet.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Observation and Modelling of Radiocarbon in Atmospheric Methane for Methane Source Identification' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Observation and Modelling of Radiocarbon in Atmospheric Methane for Methane Source IdentificationGreenhouse gas emissions are the primary cause of global climate change, and methane (CH4) is the second most important contributor after carbon dioxide (CO2). Major sources of methane are both natural (wetlands) and anthropogenic (agriculture, landfills and fossil fuels). Current efforts to assess the anthropogenic CH4 influence on climate change and the effectiveness of mitigation policies for CH4 are limited by large uncertainties in estimates of total methane emissions and their attribution to various sources by accounting-based techniques. This project will pioneer and apply innovative techniques for atmospheric observation and modelling of radiocarbon in CH4 that will enable unique quantification of fossil fuel vs. biogenic CH4 sources at regional and global scales, thereby improving the estimation and attribution of CH4 emissions of different types. The proposed work will significantly advance the frontier of current research on atmospheric methane and the characterization of anthropogenic sources on policy-relevant scales, and it has the potential to influence climate policy and industrial practices over the next 10-20 years.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'PVC-O Fittings based on MOLECOR’s Molecular Orientation TOM® technology' (FITTOM).

assistant: **Concept**

The main objective of FITTOM is the development of a new technological industrial process able to produce innovative fittings commercially competitive for water transport.Fittings are indispensable in pipe systems to connect straight pipes, fit them to different sizes or shapes and for other purposes such as regulating fluid flow.Currently, most piping systems for high pressure water transport use ductile iron fittings or injection-based plastic-fittings. The former ones are heavy and oxidises relatively easily; the latter require very expensive moulds and large amounts of raw material.MOLECOR has developed a revolutionary technology that provides reliable and user friendly systems that widen possibilities for the global pipe business. This technology demonstrated to be the highest performance, the most eco-friendly and cost-effective solution among the alternatives.The Global water market is an attractive high-volume market, which is currently estimated at about $591 billion and it is expected to reach $1 trillion by 2025. After evaluating the market trends and existing demand, we validated that FITTOM will be a promising business opportunity for MOLECOR.MOLECOR is a pioneer company specialized in the development of the latest technology applying molecular orientation to PVC pipeline solutions. MOLECOR’s proven expertise in the pipes business together with the ambition of the Boards of Directors and its outstanding staff, makes FITTOM’s success a reachable goal.Starting from an existing TRL6 prototype, and after analysing the Feasibility of the project, the current Phase 2 Project will skilfully combine technology advances with marketing and pre-sales activities to ensure a seamless transition from technology implementation to business operation.FITTOM is an excellent
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Safe and sustainable by design bio-based compounds for the next generation of liquid repellent textile coatings' to be submitted under Horizon Europe.

assistant: **Abstract**

Per- and poly-fluoroalkyl substances (PFAS) are a series of widely used compounds yet are highly problematic due to their toxicity and environmental persistence. Incoming environmental legislation is set to heavily restrict the use of these compounds, therefore there is a pressing need for safe and sustainable coatings that offer comparable liquid repelling properties. In this context the BIO-TEXTILE-SSbD project: “Safe and sustainable by design bio-based compounds for the next generation of liquid repellent textile coatings”, will utilise computational modelling methods to design and synthesise fully biobased hydrophobic and oleophobic coatings for textile applications, assessing the material properties, biodegradability and ecotoxicology of these materials. The researcher will undertake a thorough training programme centred on safety and sustainability by design (SSbD), incorporating key aspects including ecotoxicology, biodegradability, bio-based feedstocks and sustainable synthesis routes, resulting in a researcher who integrates SSbD principles in every aspect of their research. Ultimately, the aim of this project is to use Nature inspired solutions to contribute towards improving sustainability in the many EU industries that currently use PFAS, with a primary focus on textiles. As sustainable liquid repellent coatings become increasingly available, PFAS use and pollution will decrease, improving the health of both people and ecosystems.


**Keywords:** Bioeconomy, Safe and sustainble by design, Cellulose, PFAS bio-based alternatives, Textile coatings, Ecotoxicity, Green chemistry, Biocatalysis