RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Novel optical devices and measurement techniques; technology transfer and training'.

assistant: **Concept**

Foreseen ResultsThe program has a large component oriented towards training of East-European specialists developing their testing infrastructure. The GB and FR partners will develop these new components and measuring systems using the expertise of their CCE/NIS colleagues. At the same time, giving them access to their laboratories and considerable experience, ensuring successful transfer of the new technologies.Given the development of new optical coherent and non coherent techniques, novel procedures, methods and instrumentation are now used for the measurement of a variety of parameters. These techniques have evolved from their initial theoretical stage to sophisticated instrumentation, now in use in metrology, trade and industry.They have been mainly developed in laboratories in the well developed countries, due to the high refinement of the measurement methodology and high technological level of the devices concerned.The East-European partners involved in the present project have a good reputation and experience in optical systems (RO and RU), in producing of optical devices (MD) and in growing optical crystals (UA), but they lack the experience of applying their results in practise. The development of the metrological sector in these East-European countries is the vital goal of this period of transition towards a market economy and European integration.It is the goal of this JRP to stimulate and support the continuation of the high level research developed so far in these laboratories in CCE/NIS, in parallel with focusing their activity towards the development of their metrological sector. These techniques involve sophisticated measuring systems, new components and sources. These are to be developed and produced on the basis of this project. This project supports c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'FIrst NEar-TErm ApplicationS of QUAntum Devices'.

assistant: **Innovation**

Quantum technologies have set remarkable milestones in the last years, e.g. with quantum advantage experiments and loophole-free Bell tests. Despite this progress, the quantum devices we currently have, the so-called noisy, intermediate-scale quantum (NISQ) devices, are too imperfect to run textbook quantum algorithms, yet they hold great potential. With their advent, much research has been devoted to finding them a first practical application. Focus on optimization, quantum chemistry and machine learning has been intense, and the developments are closely monitored by governments and industry alike. Variational algorithms in a classical-quantum feedback loop and adiabatic algorithms have been the dominant paradigm. However, important bottle-necks remain that severely maim the performance of NISQ devices and the field yearns for a novel approach.FINE-TEA-SQUAD, FIrst NEar-TErm ApplicationS of QUAntum Devices, proposes a radically new vision: to develop a unifying framework that will yield the first practical applications of NISQ devices. The main objectives are (A) to design experimentally-friendly protocols for quantum state preparation circumventing major existing bottlenecks (high number of repetitions, noise-induced barren plateaus...) and characterize broad families of states that can be prepared in a scalable way, (B) to develop a practical certification toolset amenable to near-term devices, with especial focus on the generation of certified randomness from a single NISQ device. The key idea is to use the hardness of many-body physics in a classical verifier-quantum prover interactive protocol. This approach will overcome the existing limitations of current approaches: it will be both easy to prepare and easy to verify (C) to overcome current hardware scalability
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Enantioselective strategies for the synthesis of phenyl bioisosteres' (EnantioBioIso) targeting Horizon Europe.

assistant: **Abstract**

The obtainment of enantioenriched molecules is of fundamental importance since two enantiomers of the same drug candidate can display completely different biological properties. In recent years, an increasing interest in employing saturated scaffolds has been observed in medicinal chemistry since they provide tridimensionality and well-defined exit vectors that give access to novel unexplored chemical space, leading to a higher success in drug discovery programs. Among them, some polycyclic bridged skeletons have been identified as suitable saturated bioisosteres of aromatic rings which represent the common two-dimensional, flat moieties that are routinely employed in the drug discovery process. The aim of EnantioBioIso is to provide novel enantioselective strategies for the synthesis of phenyl  bioisosteres, enabling unprecedented approaches to obtain bridged skeletons that are of fundamental importance for medicinal chemistry.


**Keywords:** bioisosteres, asymmetric catalysis, enantioselective synthesis, Lewis acid catalysis, organocatalysis, transition metal catalysis, photocatalysis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Separation membranes for carbon dioxide removal from gas streams' to be submitted under Horizon 2020.

assistant: **Abstract**

Carbon dioxide separation, capture and utilization is expected to become a major business opportunity in the near future. Beyond current industrial needs for natural gas or biogas purification, regulatory issues imposing emission control will also contribute to a fast growth in this market. At the industrial level, CO2 separation is still an expensive process, typically based in alkaline amine solutions or cryogenic distillation, and low-cost alternatives are needed. Membrane-based technologies are the most preferred for gas purification processes due to their easy implementation and very low operational costs. However, CO2 separation through membrane systems is not competitive nowadays, due to the low selectivity and poor stability of the available materials. This weakness precludes fully exploitation of the intrinsic benefits (functional and economic) of membrane technologies.We have discovered a porous metal organic framework (MOF) able to separate CO2 from a gas stream (including methane, nitrogen, oxygen, hydrogen, olefins, etc.) that confers organic polymer membranes unique separation capabilities. Composite membranes containing this MOF exhibit unique CO2/CH4 selectivities, at least one order of magnitude higher when compared with current state-of-the-art models. This opens unique possibilities to develop an efficient, robust and affordable membrane system for CO2 separation. Our MEMCARB technology, based on inexpensive starting materials, and obtained via industrially scalable processes, could have excellent market penetration for multiple applications (from gas purification of methane feeds, to treatment of exhaust gas). Through this project we will design, build and validate a membrane-based module for gas purification. The results will be analyzed and compare
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The Sense of Commitment: a minimal analogue of commitment for joint action' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The project aims to establish the theoretical need for a minimal analogue of the concept of commitment, and to develop the notion of a sense of commitment as such a minimal analogue. The project focuses on commitments within the context of joint action, i.e. within a context that is both fundamental and paradigmatic for human sociality in general. The project aims to articulate the functions that commitments fulfill, and thus also the functions that a minimal analogue of commitment should be able to fulfill, as well as the demands that can be placed upon such a minimal analogue. In developing the notion of a sense of commitment as a minimal analogue, the project focuses on emotions and action-related cues as constitutive components of the sense of commitment. Thus, it aims to conceptualize the link between commitment and emotion, and specifically to develop the concept of feeling committed as a component of the sense of commitment, as well as to experimentally test hypotheses generated by philosophical analysis. Furthermore, it aims to conceptualize the link between habitual interaction patterns and commitment, and to develop the concept of acting committed as a further component of the sense of commitment, as well as to experimentally test hypotheses generated by the philosophical analysis.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'A framework for the fair and responsible governance of synthetic biology' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Synthetic biology aims to exercise control in the design, characterization and construction of living organisms and biological parts. No longer the domain of science fiction literature, it has progressed by leaps and bounds in recent years, accompanied by great promises and grave risks. Law and governance lag behind. Lab experimentation and field trials take place in a legal vacuum. On top of companies and research institutes, a vibrant do-it-yourself community is engaged in research, claiming to democratize innovation. Global deliberations on the environmental and socio-economic impacts have only recently begun under the auspices of UN multilateral environmental agreements, and policy-relevant academic analysis is urgently needed. Based on my academic record in international environmental law and governance of novel technologies and my empirical knowledge of intergovernmental negotiations, complemented by training in socio-legal methodologies during the fellowship, I will develop a new integrative framework for the governance of synthetic biology. It will be built upon: a) an assessment of the current state of international law and governance, including an analysis of regulatory gaps and novel normative challenges; b) an examination of existing theoretical frameworks on risk management and responsible research and innovation, including gendered approaches to risk that have been understudied to date; and c) a typology of actors involved in synthetic biology research, including an analysis of who does what, why, and how they envisage regulation, with a particular focus on gene editing in agriculture. Aiming at improving accountability and enhancing legitimacy, both of law and governance and of the innovation process, this framework will not only bridge gaps in scholarly
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Membrane-based Desalination: an Integrated Approach' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

RO is today the dominant technology in water desalination. However, some critical issues remain open: improvement of water quality, enhancement of the recovery factor, reduction of the unit water cost, minimizing the brine disposal impact. With the aim to solve these problems, an innovative approach based on the integration of different membrane operations in pre-treatment and post-treatment stages is proposed.Expected outcomes and contributions of the research are:i) the development of advanced analytical methods for feed water characterization, appropriate fouling indicators and prediction tools, procedures and protocols at full-scale desalination facilities;ii) identification of optimal seawater pre-treatment strategies by designing advanced hybrid membrane processes (submerged hollow fibre filtration/reaction, adsorption/ion exchange/ozonation) and comparison with conventional methods;iii) the optimisation of RO membrane module configuration, cleaning strategies, reduction of scaling potential by NF;iv) the development of strategies aiming to approach the concept of Zero Liquid Discharge (increasing the water recovery factor up to 95% by using Membrane Distillation - MD; bringing concentrates to solids by Membrane Crystallization or Wind Intensified Enhanced Evaporation) and to reduce the brine disposal environmental impact and cost;v) increase the sustainability of desalination process by reducing energy consumption(evaluation of MD, demonstration of a new energy recovery device for SWRO installations)and u se of renewable energy (wind and solar).The research team embodies science and engineering from both the practitioner and academic perspectives. Potential end-users and participating utilities will be involved in research activities and applications. Link ages w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'pARylation-mediated regulation of cancer pathways' in the context of a Seventh Framework call.

assistant: **Objectives**

Poly(ADP)ribosylation (pARylation) is an important post-translational modification of proteins that affects diverse biological processes such as DNA damage repair, apoptosis and transcription. The conjugation of Poly(ADP)-ribose (pADPr) to target proteins is mediated by members of the Poly(ADP)-ribose polymerase (ARTD/PARP) protein family. ADPr can be attached either as a single moiety or as chains forming poly-ADPr polymers (pADPr). The best-studied member of the ARTD/PARP family is ARTD1/PARP1, a DNA nick sensor enzyme that is activated following DNA damage. ARTD1/PARP1 is able to pARylate itself and a number of other protein targets, such as histones and DNA repair proteins, modulating their activity. Another member of this super-family is the telomeric ARTD/PARP, Tankyrase 1 (ARTD5/TNKS1), which plays an important role in maintaining telomere integrity, by pARylating its telomere partner, TRF1.  Since the discovery that defects in homologous recombination sensitise cancer cells to PARP inhibitors there has been a renewed interest in ARTD/PARPs as attractive therapeutic targets. Furthermore, similarly to kinases and phosphorylation it seems likely that ARTD/PARPs and pARylation will have significant roles in the controls of a diverse range of cellular mechanisms. Using a combined approach of RNA interference (RNAi), drug treatment and mass spectrometry-based proteomic analysis, I propose to identify and characterise novel mono- and poly-(ADP)ribosylation targets, specific to particular ARTD/PARPs. This will help to resolve how (ADP)r conjugation regulates biological processes and contributes to the survival and maintenance of cancer cells. Moreover, using pathway specific reporter cell lines I will address the specific contribution of mAR/pARylated proteins for the r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Europe Science and the City: Promoting Scientific Culture at local level'.

assistant: **Innovation**

The Science in Society Forum held in Brussels last March underlined the need for a greater institutional commitment across Europe in raising the profile of science as an integral part of our culture. Despite the advances made since the launch of the Commissions Science and Society Action Plan, little has been done so far to erode the borders between the two cultures and promoting scientific culture is not usually an issue of our cultural agendas.Besides, most actions are implemented at a national level while the municipality is the closer administration to citizens and, probably, the most flexible in incorporating new public engagement tools. This proposal addresses the above two key issues. ESCITY focuses on creating the core for a community that brings together regional and local governments and social researchers across Europe to exchange information and best practices with the emphasis on strategies that place the promotion of scientific culture within the cities and regions cultural policies. The project aims to settle the basis for a wider and lasting network, able to act as a lobby. ESCITY has four Areas:1. To provide a broad forum for scientific culture issues across Europe.2. Benchmarking the promotion of scientific culture at regional and local level.3. To organise a European Conference to be held in Barcelona in 2007, which the city has declared Science Year. Prior, contacts will be made with other European networks of cities in order to gather experiences, concerns and suggestions relevant to ESCITY and identify potential participants and network members.4. To engage in a lobby strategy by publishing an action guide to be distributed to European governments, its contents being the forum conclusions, a list of best practices.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Foucault's manuscripts on phenomenology (1950s) at BnF archive: a digital approach to the edition' (1950s) targeting Horizon 2020.

assistant: **Abstract**

EDIFOU’s aim is to explore, organize, digitally index and disseminate Michel Foucault’s unpublished manuscripts of the 1950s and the early 1960s on phenomenology, psychology, psychopathology, and anthropology (collected since 2013 at the Bibliothèque Nationale de France Archive). This part of Foucault’s work is still totally unknown today, therefore EDIFOU aims to provide researchers with a new corpus, which is destined to become a reference work in the field of humanities. Together with proposing original theoretical analysis, EDIFOU meets the most current issues of digital humanities especially related to cultural heritage. EDIFOU has indeed the aims to achieve an original editorial program, and generate new  knowledge by means of the development of innovative digital tools. As an external scientific consultant of Triangle’s ANR project 'Foucault Reading Notes', I have already tested the usefulness of the digital tools that have been developed in this framework up to now. EDIFOU’s aim is now to contribute to their improvement and further development. EDIFOU is highly stimulating and offers intellectual challenges. It is an ambitious project that requires not only specific scientific competences in the fields of philosophy, social sciences, and digital humanities, but also those personal and practical skills that enable a researcher to work in a team. At this stage of my career, I can rely on an excellent reputation in the international community of scholars in both the fields of Foucault studies, and history and philosophy of psychiatry. The quality of the research environment, supervision, training, and host facilities at Triangle-ENS de Lyon will give me the important opportunity not only to disseminate my research through diverse communication and outreach strategi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Silicon solar cells with Low Environmental footprint and Advanced interfaces'.

assistant: **Concept**

The SiLEAN project, involving 2 research institutes, one University partner, 4 SMEs and 1 industry partner, deals with the development of advanced innovations to tackle the major drawbacks of silicon heterojunction solar cell technology, namely the high energy and material demand for Si wafer manufacturing, limited current generation, and the consumption of scarce materials like silver, bismuth and indium. Within the scope of the project, we will directly grow the wafers from the gas phase with low temperature processes, apply alternative passivation concepts that show higher optical transparency, develop indium-free contact layers and apply silver and bismuth-free metallization with all-in-one cell interconnection and encapsulation. We aim to achieve >25.5% solar cell efficiency and >23.5% module efficiency with 50% lower costs for Si wafers and contacting, as well as up to 75% lower carbon footprint. All processes applied allow upscaling to larger sizes as well as high manufacturing throughput. Eventually, the developments of SiLEAN will pave the way for a new, lean, generation of heterojunction solar cell technology that will both increment the energy conversion efficiency and unlock production at terawatt-scale.


**Keywords:** silicon carbide, transition metal, heterojunction, SHJ solar cells, epitaxial wafers, metal free, low environmental impact, nanotexture, mini-modules