RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The evolvability of bacterial multicellularity' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

There are numerous evolutionary origins of multicellularity. Yet, only in a few cases was the origin of multicellularity also followed by an enormous diversification of multicellular forms and functions. This raises the question what determines the evolvability of multicellular phenotypes, i.e. their capacity to undergo evolutionary change? I will study the evolvability of one of the simplest forms of bacterial multicellularity: colony formation in the Bacilli. Despite their simplicity, Bacilli can express a wide range of colony morphologies. The physical forces that shape these morphologies are well understood. In addition, there is a detailed understanding of the gene regulatory network (GRN) underlying colony formation and ample of genomic data. I will study how the GRN underlying multicellularity affects its evolvability. First, I will determine which evolutionary changes in the GRN are associated with the diversification of colony morphologies. To this end, I will construct a phylogenetic tree of the Bacillales, compare all genomes and identify the genetic changes that correlate with changes in colony morphology. Second, I will determine if and how these genetic changes give rise to changes in colony morphology. I will construct Bacillus subtilis mutants, which harbor the identified genetic changes, and examine how their colonies develop. Since colonies come about through the feedback between cells and their environment, I will use a unique combination of state-of-the-art biotechnologies to trace the transcriptomic and environmental changes in the colony over time. This will give an extraordinary detailed account of colony development in the Bacilli. Finally, I will examine why the morphological diversification of colonies was favored by selection, by studying the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Scale-up of INNER MAGIC and INNER REFLECTION: Virtual Ultrasound Sensors for Smart Devices.' to be submitted under Horizon 2020.

assistant: **Abstract**

Smart device manufacturers require constant innovation in order to improve their products while simultaneously reducing costs. Hardware-based solutions are expensive, requiring dedicated sensors and long deployment times to fully integrate them into devices, since they must be manually tuned and calibrated for each new type of application. This makes it difficult to customise such devices for different market segments and end-user needs. Furthermore, extra hardware requirements often compromise a device’s design, increasing their bulk and rendering them old-fashioned. Many hardware-based solutions also increase the risk to a user’s privacy and data security, such as those solutions involving cameras. As a result, manufacturers are adopting software-only solutions instead of hardware. However, they do not yet have a presence detection or gesture recognition solution ready for mass commercialization.Elliptic Labs is the world leader in ultrasound sensing software for smart devices, enabling touchless interactions and gesture interpretation. INNER MAGIC and INNER REFLECTION (IMIR products) are the first-of-their-kind integrated solutions for non-intrusive user presence detection and intuitive gesture recognition, transforming smart devices into genius devices. The aim of the IMIR-UP Phase 2 project is to fully mature our award-winning and patented technology for easy, mass-scale (“plug-n-play”) deployment in any consumer electronic smart device without requiring supplemental hardware (software only). Bringing our innovative IMIR products to the mass market will positively disrupt existing touchless sensing technologies, resulting in an improved user ability to intuitively interact with their smart devices via a natural extension of normal human behaviour. We estimate that
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Carbon – Ice Composite Materials: Water Structure and Dynamics at the Carbon Interface' (CARBONICE) under Horizon 2020.

assistant: **Objectives**

Carbon and water in its various states of matter make up a substantial proportion of our Universe. The two materials are highly dissimilar with respect to their chemical and physical properties. Elemental carbon is even often referred to as a hydrophobic, ‘water-hating’ material. Yet, the two materials often coexist and critical processes take place at the interface between these unlike chemical species. This includes the hydration shells of hydrophobic moieties in biomolecules, clathrate hydrate materials where water molecules crystallise around hydrophobic guest species as well as icy comets which are often black due to the presence of carbon at their surfaces.The aim of the CARBONICE project is to investigate the interface and interplay between water and carbon in detail. Using new and innovative experimental strategies, the water molecule will be placed in a variety of different yet highly relevant carbon environments. This will give us unprecedented insights into how water hydrates hydrophobic species which is highly important in the context of hydrophobic interactions. Investigations into how carbon species influence phase transitions of ice will give new insights into crystallisation phenomena but will also reveal the factors that lead to the formation of either ferro- or antiferroelectric ices. Creating carbon – ice composites in the lab as they exist on comets will enable us to understand the complex weather cycles on comets and may help explaining the unusual surface features recently identified by the Rosetta space probe.In summary, this truly multidisciplinary project opens up a new spyhole to critically important processes at the water – carbon interface. The results will have an impact on the space, atmospheric and general materials sciences but will also
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Homotopy theory of quasi-coherent sheaves on stacks' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

In the last decade there has been a growing interconnection between algebraic geometry and homotopy theory. This project is part of that exciting development. The primary researcher has developed a homotopy theoretic approach to the theory of stacks. As part of this project the PI will apply this approach to the study of quasi-coherent sheaves on stacks and questions of representability by algebraic stacks. The PI plans to prove a series of structural results about the categories of quasi-coherent sheaves, including existence of pushforward and pullback functors, internal Hom, completions, and localizations, for a very general class of stacks. These results can then be applied to understand the structure of the categories of quasi-coherent sheaves and should have important applications in algebra and topology. In particular, the PI will show how these statements can be applied to the moduli stack of formal groups leading to new results in stable homotopy theory.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Repository-wide screening for bioactivity and protein binding  using small molecule mass spectrometry data' (BindingShadows).

assistant: **Innovation**

Bioactivity and ligand binding remain central topics for understanding protein function, for drug discovery and toxicology. Mass spectrometry (MS) allows to detect thousands of small molecules in a biological sample with a single experimental run. Compound annotation is carried out using tandem MS. I will develop machine learning models that predict whether a query small molecule has a certain bioactivity or is binding to a certain protein, where the only information we have about the query molecule is its tandem mass spectra. The identity and molecular structure of the query small molecule is unknown; it is unknown to the models, to me, and potentially even to mankind. Clearly, bioactivity and binding are two flavors of the same problem, and the differentiation is solely driven by the available training data. Notably, elucidating the structure of the small molecule is not the focus of the project, and may be postponed until after experimental confirmation. Models will not predict one particular bioactivity or protein binding, but rather tens in parallel. Evolution has, through variation and selection, optimized the structure of small molecules for tasks such as communication and warfare, and the pool of natural products is enriched with bioactive compounds. My project will allow to harvest the information.I will apply my models at a repository scale, screening millions of tandem MS spectra in thousands of datasets for small molecules that are most likely to have bioactivity or to bind. I will also make my methods available through our well-established SIRIUS platform, allowing users to derive information about bioactivity without the need of additional experiments. I will enable the worldwide community to hunt for drug leads or unknown toxic compounds, without the need
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Fully Biocompatible Intrabody Nanoscale Communication System to Foster Novel In Body Diagnostics and Monitoring Systems' (BeNiFIt).

assistant: **Innovation**

Early detection is crucial in improving treatment outcomes and alleviating the burden of chronic diseases, as emphasized by the EU Mission: Cancer. In vivo dianosgtic approaches have been shown to eliminate a couple of post-processing stages, but no significant reduction in turnaround delays has been reported, in addition to being costly, bulky, and invasive. The next natural step in innovation would be to reduce turnaround delays from the present best of 10,000 minutes to within a few tens of minutes, a 1000X improvement, which BeNiFIt aims to introduce. The goal of the BeNiFIt project is to show that intra-body nanoscale communications (IBNC) can be used to make in-vivo diagnostics possible. This will pave the way for more advanced early detection and real-time monitoring methods that are minimally invasive, low-cost, and have small turnaround delays. Through BeNiFIt, I will demonstrate the competence of IBNC for in vivo detection of biomarkers with high accuracy by using nanomachines equipped with biosensors. A cooperative sensing approach will be developed to maximize the sensitivity and specificity of the biosensors, thus reducing the number of false positives/negatives caused by the presence of other molecules. In addition, I will design an approach to integrating the sensing and communication hardware to meet the hardware requirements of nanomachines. A near-field magnetism-based system and passive communication architecture will be implemented to ensure ultra-high safety and energy efficiency.  Lastly, an open-source system-level simulator will be developed, spanning microscopic to macroscopic scales, to analyze the impact of the design choices on the system’s performance. The KPI targets of BeNiFIt include >95% detection accuracy and a 10X reduction in treatmen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Global change vulnerabilities in the barents region: linking arctic natural resources, climate change and economies' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The European North will be subjected to significant changes in climate over the next few decades. The complex but poorly understood interrelationships between components of the arctic system may lead to positive or negative feedback to these resulting in enhanced vulnerability. BALANCE will assess the vulnerability of the Barents Region to climate change through the description and quantification of major links between essential environmental and societal components and will be based on a common modelling framework for these components. A holistic, interdisciplinary approach to the assessment of climate change vulnerabilities, a close link between the project scientists and the major stakeholders in the region as well as potential key (institutional) users of our project results and the utilisation of existing data and information from earlier and ongoing EU projects, are key characteristics of the project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Digital Mock-up Process Simulation for Product Conception and Downstream Processes' (DMU-PS).

assistant: **Innovation**

Objectives and content Current industrial practice in automotive, aerospace and other manufacturing industries involves the creation of physical product models (physical mock-ups) as a help to designers, manufacturing planners, etc.. The objective of the(se) project(s) is to depart from this practice and develop the technology that allows designers, manufacturing planners and even the management to work on Virtual Products / Digital Mock-Up's (DMU). They can make decisions related to the concept, design and all downstream processes. This technology will allow companies to work in a concurrent engineering environment independent of their size and product configuration. To achieve this goal a cluster of projects including modelling, simulation, visualisation, etc. (see figure) is proposed. Within this cluster of projects the objective of the DMU-PS project is to develop the technology which allows the designer to model and simulate assembly, disassembly, service and maintenance processes while he is designing products and subassemblies. The benefits of this technology will include substantial reduction of development time (at least 10%) and manufacturing cost, such as reduction of Physical Mock-up's, and a dramatical increase of product launch quality. It is expected that the process simulation technology will benefit not only automotive and aerospace industry but other industrial manufacturing sectors such as house appliances, machine building industry, ship building etc..The composition of this consortium includes end users, technology vendors and universities and guarantees the successful performance of the project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Fighting childhood obesity to stay healthy all over the life' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Obesity rates in late teens have increased in Europe from 6% in 1980 to 32%, with long-lasting effects on the prevalence of severe obesity, diabetes and cardiovascular disease, premature death and disability. Efficiently fighting adult obesity is difficult but prevention and treatment of obesity have proven to work better at young ages. OBELISK goal is to cut the roots of the pandemic of obesity in Europe targeting children first. OBELISK is focused on elucidating, Predicting, Preventing obesity and bringing Precision medicine for children with obesity. OBELISK medicine is also Participative (4P), leveraging the potential of social innovation through engagement with families, scientific and medical communities, daycare, schools, municipalities, industries to achieve success.OBELISK objectives are: 1/ to bring breakthroughs in the molecular mechanisms by which causative factors interact to drive (or prevent) the transition from normal weight to obesity during childhood and to develop and exploit for prevention and treatment early predictive proprietary tools; 2/ to identify at least 3 novel childhood obesity genes with the prospect of identifying additional drug targets; 3/ to demonstrate the utility of targeted approaches to prevent childhood obesity; 4/ to bring breakthroughs in childhood obesity treatment including a real-life clinical study of a promising existing drug (GLP1R agonist) to reverse obesity in people with mutations predisposing to early severe obesity; 5/ to exploit the project results and disseminate best practices to prevent and treat childhood obesity, implementing education programs and translating OBELISK clinical results into guidelines and proposals for policy makers to change obesity care; 6/ to facilitate networking and exchanges with other acti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for '“Thomas Aquinas’ Summa Theologiae Ia IIae translated by Demetrius Cydones and Bessarion’s incomplete Compendium of the translation – A Critical Editio Princeps”' in the context of a Horizon 2020 call.

assistant: **Objectives**

The proposed Project is the critical edition (editio princeps) of the Greek translation of Thomas Aquinas’ Summa Theologiae Ia IIae by Demetrios Cydones and of its partial Compendium by Cardinal Bessarion. The proposed research is part of the “Thomas de Aquino Byzantinus” Project, which is held by the Royal Holloway University of London and the Department of Education of the University of Patras. This project aims to provide scholarship with critical editions of the Byzantine translations of some of Aquinas’ writings and, thus, to contribute to the research on the relations between the Catholic and Orthodox theological and intellectual traditions. As regards the proposed research, just a few studies deal with the influence of Scholastic moral philosophy on Byzantium. Thus, the proposed critical editions will reveal the influence of Thomas Aquinas’ moral philosophy on Byzantine world and shed more light on the philosophical and theological dialogue among distinguished scholars and theologians in the Greek East and the Latin West in a period of intensive intellectual creativity. In this aspect, the relations between the Latin and Byzantine culture will be seen from a different point of view and the History of Ideas in Europe will be enriched. In this sense, the publication of these texts will become an indispensable tool for scholars and students of Byzantine and Western European intellectual history. Considering the quality of the proposed research, my competences in critical editions, and my research experience on Byzantine Thomism, I firmly believe that the proposed Project is the appropriate next step in my career development. For this reason, I decided to apply for MC – IF, since this Fellowship will give me the opportunity to join an excellent Department in the fiel
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Molecular ecology of the photosynthetic procaryote prochlorococcus, a key organism of oceanic ecosystems' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

The application of molecular biology to oceanography is still little developped, especially in Europe. However, it is a very promising field for marine biologists, who have become able to address key ecological questions with a level of resolution never attained by previous methods. It is now possible to directly use molecular probes on field samples either to assess the extent of genetic diversity in genetically related marine organisms or to probe their nutrient status. The present project is centered on an important and recently discovered genus of marine photosynthetic microorganism: Prochlorococcus. This prokaryote proliferates in oligotrophic areas, including the Mediterranean and Red Seas, is the tiniest and numerically the most abundant photosynthetic organism on Earth and accounts for a large part (up to 50%) of the photosynthetic biomass and primary production in these areas. Moreover, Prochlorococcus has the advantages of being easily discriminated and counted by flow cytometry and of possessing a unique pigment signature (divinyl-chlorophylls a and b). In addition, natural isolates from a variety of sites and depths are available under laboratory conditions. Prochlorococcus therefore constitutes an outstanding biological model for ecological studies. In the framework of the Promolec project, we will: 1) study the intrageneric diversity of Prochlorococcus in the laboratory and in the field, with an effort to correlate the phenotypical and genotypical characters, 2) characterize the genes encoding cellular components responsible for ecologically significant functions (photosynthesis, growth, responses to nitrogen and phosphorus limitation) and study their regulation, 3) develop a set of molecular probes and screen these functions in natural Prochlorococcus pop