RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Coherent diffrAction foR a look Inside Nanostructures towards atomic rEsolution: catalysis and interface'.

assistant: **Concept**

Heterogeneous catalysis of nanoparticles has recently emerged as highly promising way to speed up catalytic processes due to their far higher surface area compared to bulk materials. But they face significant challenges in achieving high catalytic activity and sufficient durability. A key problem has been that all existing approaches to the characterization of atomic scale phenomena in these materials either lack structural specificity or can be employed under highly unrealistic catalytic environments. As an example, operando x-ray catalysis has often been carried out under idealized conditions and averaging information from macroscopic facets. This approach suffers from the lack of transferability to nanocrystalline systems. To tackle this problem, I am developing new state-of-the-art in situ techniques based on coherent x-ray scattering and complementary chemical characterization, with which I will optimize catalyst and reactor operations simultaneously. This is the ambition of the CARINE project to study in situ and operando the structural evolution of catalytic nanoparticles in realistic conditions during reaction by using the unique capabilities of coherent diffraction Bragg imaging (CDI). My proposed work builds on my recent exciting proof-of-concept experiments using Pt nanocrystals that demonstrate the sensitivity and spatial resolution of CDI under liquid conditions. As dedicated instruments for CDI have just reached user operation, it is only now that this new imaging technique can be applied during reaction and can probe structural changes of individual nanocrystals under conditions where up to now, no other techniques could probe the relevant parameters. My project will shed light into most relevant unsolved issues (durability, activity…) that limit the effi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Continuous Diaphragm Monitoring for mechanically ventilated patients', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Mechanical ventilation (MV) is one of the most common interventions implemented in the intensive care unit (ICU). MV is associated with a number of complications such as atrophy, muscle weakness, pneumonia, tracheal stenosis and baro/volutrauma. Complications increase in likelihood with duration of ventilation, and studies show that 15% of the patients that are extubated must be put back on mechanical ventilation for extended treatment. Timing and adjustment of MV is therefore critical to ensure safe recovery. MV has enormous costs for healthcare systems with US$1,500 per patient per day. MV patients in ICUs account for 6% of all ventilated patients but consume 37% of ICU resources. With an estimation of 1.35 million MV patients in the EU for an average of 4-5 days, this represents the enormous expenditure of US$3.3 billion (€3.1 billion) annually. Respinor has developed a novel, small and flexible ultrasound sensor (DiaMon) that provides precise, continuous information on diaphragm movement over prolonged periods of time without the need of direct manual operation or expertise monitoring. The information from DiaMon will enable ICUs staff to optimise the interaction between patients and the mechanical ventilator, reduce ventilation time, and significantly reduce extubation failures. With DiaMon, Respinor targets ICUs to offer a cost-efficient and innovative diagnostic tool that will substantially improve an expensive and critical medical procedure that is common – and increasingly growing in demand - in the global hospital healthcare market.The accomplishment of the project objectives (Phases 1 and 2) will bring major benefits to Respinor with a cumulated turnover of 103 million € in 2025 in the mechanical ventilation market. DiaMon will furthermore greatly improve qua
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'A community of surface bots for creative storytelling'.

assistant: **Objectives**

Interactive digital storytelling systems can be used to foster the development of creativity skills and enhance social awareness on our societal issues, aspects recognized to be strategic for our own future sustainability and competitiveness. However, current interactive storytelling approaches face important limitations in the implementation of digital characters. On the one hand, some systems provide very capable socially virtual agents used as characters, but enacted in a virtual world where technology is rather a barrier to effective creative thinking and collaboration. On the other hand, settings with tangible objects facilitate discussion in groups as well as the development of relevant critical social skills, but with characters unable to show advanced smart capabilities to enrich storytelling for a more effective process.Hence, given the current state-of-the-art of technology, the main objectives of COBOTNITY are: to timely provide an affordable community of hybrid artificial agents (called surface-bots) capable of drawing a high range of digital expressions while providing tangible interaction to be used in collaborative creative storytelling; and, to provide a better understanding on how a surface-bot community can effectively be used to foster creative thinking and social awareness on societal issues. The project proposal draws on the knowledge of HMI on interaction with artificial agents (both virtual and robots) along with its expertise on interactive storytelling, as well as on the candidate’s experience on creativity in collaboration. COBOTNITY is relevant to the MSCA Work Programme because it will allow developing new research competences, ensuring advantageous skill and knowledge transfer, and opening new perspectives in diverse sectors for potential te
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Cancer-Cell Specific Organometallic Ru(II) Complexes as Photosensitizers in Photodynamic Therapy' (II), addressing dissemination and exploitation.

assistant: **Impact**

In this project, I plan to use cyclometalated Ru(II) polypyridyl complexes as novel photosensitizers (PSs) in photodynamic therapy (PDT) to fight cancer. Such compounds are easier to synthesise than the well-known porphyrins and have a higher lipophilicity (to better cross the cell membrane) and a bathochromic shift of the absorption (to irradiate at low energies) than the usual Ru(II) polypyridyl complexes. Furthermore, I plan to couple maleimide moieties to these complexes to directly bind cysteine-containing biomolecules (i.e. HSA) and therefore, overcome the selectivity issues observed for the typical PSs. The use of bisbenzimidazoles as ancillary ligands will allow to tune the properties of the complexes in view of having the most red-shifted absorption. Computational chemistry will be first used to design the complexes, and after the synthesis and complete characterization, biological experiments will be performed to evaluate their potential as PSs. A secondment under the supervision of Prof. Clotilde Policar will allow localizing the compounds prepared by the use of a synchrotron-based imaging technique (X-ray fluorescence) as well as single cell ICP-MS, which will help to detect the metal inside the cell and figure out the biodistribution of the complexes. The multidisciplinary scope of this work along with their innovative aspects to selectively cause death of cancerous cells, make it a ground-breaking proposal. In addition, working in one of the best universities of the world, under the supervision of Dr. Gilles Gasser and Prof. Clotilde Policar will promote my scientific career.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Autonomous forest fire detection and prevention aid system integrating remote multisensor terminals.' (AFFIRM).

assistant: **Concept**

The AFFIRM project consists of the development of a complete system for prevention, control and automatic detection of forest fires. The system is made up of a certain number of ground remote terminals linked to an operations centre through a communication network by satellite. The main objective of AFFIRM is to provide a global and integrated solution to the problem of forest fire prevention, maintaining a real time data base of fire risk parameters, forest fire detection, through the automatic identification of any alarm, and helping in the subsequent human actions to control and eliminate the fire, providing useful real-time data in this phase of the operations. Moreover the functional objective of AFFIRM shall be completed with an economic objective allowing the results of AFFIRM to become a commercial product. To achieve these objectives the following are considered key issues in AFFIRM: - The fire detection mechanism, that will be based on the smoke plume identification. - The image compression algorithms, allowing to transmit the remote images to a control centre through a narrowband channel. - The satellite access method, optimising the utilisation of the communication channel. - The data processing, allowing to integrate in a common data base the data coming from diferent sources: meteo sensors, multispectral CCD, etc. Substantial part of the key development will be based on the results of already succesfully developed projects by the AFFIRM consortium members in previously funded EC programes; thus, maximum benefit will be obtained with the presently proposed R & D effort. Forest Fire, Detection, Satellite, Image Processing, Smoke Plume.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Phages against MDR Enterococcus faecium' in the context of a Horizon Europe call.

assistant: **Objectives**

Due to its multidrug resistance (MDR), Enterococcus faecium (Efm) poses a challenge to the healthcare system and renders most standard antibiotics useless. Bacteriophage (phage) therapy has resurfaced as a treatment strategy for bacterial infections due to increasing antibiotic resistance. Its advantages include specificity, low side effects and production costs, especially when used in combination with standard-of-care antibiotics. Phage therapy has been successful in compassionate use, but its wider implementation is hindered by a lack of knowledge on which antibiotics phages synergize and the mechanisms behind remain elusive. Our project is unique in that it aims to enable the use of conventional antibiotics in MDR Efm through phages. We want to explore which antibiotic classes phages synergize with, which survival strategies Efm uses against phages, and how host factors influence the ability of the antibiotic-phage combination to kill Efm.First, we will investigate phages' interaction with different antibiotic classes against Efm. We will explore the dynamics of phage-antibiotic combinations and whether they are additive, synergistic, or antagonistic.Second, potential phage survival strategies of Efm will be investigated. Additionally, membrane vesicles will be investigated as a potential survival strategy against phages, and their ability to act as a decoy and protect the bacterium from phages will be studied.Third, we will investigate the impact of host factors on the phage-antibiotic killing of Efm, to see whether they can enhance or suppress the phage-antibiotic killing.This approach will provide a deeper understanding of the phages-antibiotic interaction against MDR Efm strains, as well as potential survival systems of Efm which may also shed light on possible
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'European Communities Aeronautics REsearch Plus'.

assistant: **Innovation**

This proposal follows up on the ECARE project (2003-2005), funded under FP5. It is planned as a amplification of the tasks as of the results of the first project. The final objective is to better involve research-intensive aeronautical SMEs into EC funded research (Integrated Projects and STREPs), following a method adapted from the ECARE project, its identified best practices and its lessons learned: - A core group of eight partners, including 6 Aeronautical regional clusters and benefiting from the suppor t of an already established group of 11 other clusters will further expand in order to involve up to 30 regions. - Information seminars on FP7 opportunities will be organised, and SME capabilities will be assessed in order to expand the already existing d atabase of companies to 300 entries. Partner search functionalities will be installed on the projectâ??s website. - SME capabilities will be relayed to the IP co-ordinators after fine-tuning by ECARE+. Already ongoing collaboration with AeroSME and SCRATC H will be maintained and amplified. Dialogue will be established with the Regional governments or programmes as with the large companies in charge of the Aeronautical IPsâ?? co-ordination. The project duration will be 30 months, in order to cover the end o f FP6 and the launch of FP7.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Lean Product and Process Development'.

assistant: **Concept**

The proposal is addressing the need of European manufacturing companies of a new model that go beyond lean manufacturing to ensure the transformation of the enterprise into lean environment. This is to response to the customers and market demands of value creation incorporating sustainability, culture and customisation. A significant change in enterprise performance can come from the adoption of lean thinking throughout the entire product life cycle. The aim is to develop a new model based on lean thinking that will consider entire product life cycle, providing a knowledge based environment to support value creation to the customers in term of innovation and customisation, quality as well as sustainable and affordable products. This will be called Lean Product and Process Development (LeanPPD) paradigm. The required knowledge for value creation in LeanPPD model will be developed based on the European standard and open architecture to ensure data and knowledge integrity and to provide a lean environment across the product life cycle and the supply chain. The project proposes to develop novel set-based lean design tools that ensure the concurrent consideration and development of lean product design as well as it associated lean manufacturing system.  The user driven approach will be ensured by the six business cases (BC) provided by the end-users from different sectors in the consortium. These BCs will serve to derive requirements upon the tools, methodology and models being developed , to test the solutions developed and will serve as industrial demonstrators of the proposed concept.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Waste of hospitals and alternative treatment' in the context of a Fourth Framework call.

assistant: **Objectives**

The alternative methods for the treatment of medical waste, instead of the incineration by the hospital itself include non-incineration technologies, like: steam autoclaving, chemical treatment, microwave, infrared radiation, gamma radiation and combustion technologies, like: plasma, pyrolysis and gasification systems. The combination with recovery of energy (cotton), the re-use and the recycling of plastics (40% of the waste) of glass and metals becomes possible. The technical and economic feasibility depends on the successful implementation of effective machines for the on-site treatment at the point of waste generation. It improves the safety of the workers and reduces the transport of hazardous waste. The technical and economic problem is the optimal combination of the Health aspects (inactivating microorganisms) and the environmental (identification, sorting, recovery, re-use and recycling of material or energy) safety (operations), logistic (transport, packaging, reduction of volume) and economic (costs) aspects. An optimal solution has not been developed yet. It needs research. The first research objective is: to find the best technology or combination of technologies for the systematic solution of this problems, especially the level of microbial inactivation and the effectiveness of inactivating microorganisms in combination with the re-use and recycling (recovery of usable substances from toxic waste). The second research objective is: to combine this solution with the following special needs from health care institutions: miniaturisation, the monitoring of the disinfection process, automatic shut-down, improved logistics, automatic loading, un-loading and packaging, emission control and sorting and selection for the re-use or recyciing of waste and the recover
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'T for the Black Sea region' in the context of a Sixth Framework call.

assistant: **Objectives**

The Black Sea Economic Cooperation (BSEC), despite its heterogeneous membership especially regarding the status of its member states in relation to the European Union, has successfully built, over the past 12 years, a complex institutional structure and is emerging as a significant actor of new European regionalism in an area of growing strategic importance. While the primary focus of BSEC has been to enhance regional trade and economic cooperation, the Organization has sought to diversify its activities in new areas of interest and competence. Prominent among these areas is the considerable S&T potential that exists, despite the difficulties most of the countries in the region have faced over the last fifteen years.Since the Black Sea is moving in to a new era of stability and growth, and since some of the regional actors are currently involved in the EU's research activities through their association with the Framework Programme, it appears necessary to elaborate an Action Plan in S&T, in ord er to: -Re-confirm the political will for cooperation in S&T among the countries of the BSEC region and also enhance the cooperation with EU, contributing therefore to the opening of the European Research Area; -Define the most promising fields and pr iorities for collaboration in research and innovation among the BSEC countries extending also to other New Independent States ('broader BSEC'); -Sketch out an early version of a structured cooperation mechanism at the BSEC regional level in the sphere of science and technology and procedures for interaction with the relevant departments of the European Commission; It is envisaged that the adoption of the Action Plan at Ministerial level involving also high-level EU participation will constitute a valuabl e basis for the EU's future