RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'New cooperative business models and guidance for sustainable city logistics' (NOVELOG), addressing dissemination and exploitation.

assistant: **Impact**

Urban areas represent the greatest challenges for freight transport and service trips, both in terms of goods distribution and service allocation performance, and environmental impacts (air emission, traffic congestion, road safety, accidents and noise). The salient scope of the proposal is the enabling of knowledge and understanding of freight distribution and service trips by providing guidance for implementing effective and sustainable policies and measures. This guidance will support the choice of the most optimal and applicable solutions for urban freight and service transport, and will facilitate stakeholder collaboration and the development, field testing and transfer of best governance and business models. This shall be achieved through:- the targeted understanding of urban freight and service trips, fostered by data collection on city logistics,- field testing and implementation of representative city logistics measures, - the development and application of a modular, integrated, evaluation framework for the assessment of these measures- the development of a typology between cities and potential city logistics components, and - the provision of guidance to cities, shaping consistent implementation channels for successful solutions, all according to the local needs and constraints. These activities will be accompanied by the production of practical tools that could support the take-up impact of NOVELOG project to wider international city and industrial networks and beyond the project's lifetime. NOVELOG will contribute to the European Commission's research and policy agenda through the generation of sound knowledge that introduces a new approach to guidance strategies that supports a more sustainable urban environment.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Testing for post-copulatory female choice in a cephalopod' (SQUIDMATE) under Sixth Framework.

assistant: **Objectives**

Empirical studies and theoretical discussion in the field of sexual selection suggest that male-male competition and female choice have postcopulation equivalents in polyandrous systems. Postcopulatory processes may affect sexual selection by increasing heterogeneity of fertilisation success of males. Sperm competition, the postcopulatory equivalent of male-male competition, has broad empirical and theoretical support. Postcopulatory female choice however, has proven difficult to demonstrate and is still the subject of controversies. One form of postcopulatory female choice, where females can discriminate between and differentially utilise the sperm of different males, is called sperm choice. One way to assess if sperm choice is occurring is to investigate the mechanism by which a female differentially use sperm from various males. A few studies have reached that goal by demonstrating that female chose the sperm of unrelated male over the sperm of relatives. Unambiguous tests of whether sperm choice is or is not occurring, are needed to test the generality of this process, and therefore its importance in evolution. This proposal aims to use molecular genetic techniques to determine patterns in sperm storage and paternity of wild-caught squid, to assess whether females have the potential for sperm choice. Loliginid squid have unique advantages related to novel aspects to their biology that will permit to acquire empirical data which support or refute this hypothesis. The project will determine:1. The incidence and pattern of multiple paternity within broods;2. If switches in paternity of embryos occurring along the length of egg strings is a consistent phenomenon in the wild.3. If the relationship between paternity and spermatophores located within particular deposition
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The Researchers' night 2006 in Norway' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

The Researchers' Night 2006 in Norway is a nation-wide promotion effort in line with the objectives of the call FP6-2006-Mobility-13 of the Commission, planned to be arranged on the evening of 22. Sept., 2006.As in 2005, the Researchers' Night 2006 coincides with the opening of the Forskningsdagene" (Norway's National Science Week, 22.09-011006), during which around 1000 events are arranged by 200 local/regional representatives all over Norway, organised and coordinated by the Research Council of Norway (RCN). "Forskningsdagene" is well established and well covered by the media. The RCN aims to copy, supplement and improve last year's nation-wide arrangements on the "Researchers' Night" 220906.This has been approved by the local organisers of the "Forsk ningsdagene 2006", who agree that the RCN submit Norway's proposal for the Commission. The "Researchers' Night 2006" in Norway aims to bring the public at large - as well as the media - in close contact and dialogue with researchers under informal and innovative circumstances."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Senolytic CAR T cells as novel therapeutic concept for solid tumors and senescence-associated diseases.'.

assistant: **Innovation**

The adoptive transfer of T cells expressing CD19-directed chimeric antigen receptors (CARs) has yielded remarkable efficacy in patients with hematological B-cell malignancies. CARs are a class of synthetic receptors that reprogram T cell specificity, function and metabolism. Engineered T cells are applicable in principle to other cancers and diseases, but clinical success will critically depend on further progress to overcome current limitations such as antigenic heterogeneity or impaired T cell trafficking and function. We propose to develop CAR T cells targeting senescent cells as a novel therapeutic concept for cancer and senescence-associated diseases. Cellular senescence is a stress-response program characterized by stable cell cycle arrest that serves as a potent tumor-suppressive mechanism. Conversely, accumulation of senescent cells generates a chronic inflammatory milieu, which contributes to a plethora of pathologies, such as liver or lung fibrosis and can even promote tumor progression. Our preliminary data demonstrate that CAR T cells can efficiently clear senescent cells, providing therapeutic benefit in a murine model of liver fibrosis. We thus firmly believe that senolytic CAR T cells have broad therapeutic potential. To this end, we will apply innovative engineering strategies to develop modular CAR designs tailored to senescence-specific requirements. We will determine safety and efficacy of senolytic CAR T cells in murine models of cellular senescence and solid tumors. Importantly, we will evaluate combined treatment approaches of senescence-inducing therapies with CAR T cells targeting senescent and proliferating tumor cells. Finally, we will investigate engineering tools to optimally direct senolytic CAR activity to mediate durable tumor regression.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'European Facility for innovative reactor and transmutation neutron data' (EUFRAT).

assistant: **Concept**

The Neutron Physics Unit of the EC-JRC-IRMM (Geel, Belgium) is equipped with a unique scientific infrastructure of European relevance. This research infrastructure, which to a large extent is operating for highly accurate neutron cross-section measurements, includes two accelerators facilities:  GELINA is a 150 MeV electron accelerator serving as strong white neutron source for high-resolution neutron time-of-flight measurements. The 7 MV Van de Graaff facility is an electrostatic accelerator for the production of continuous and pulsed proton-, deuteron- and helium ion beams which is serving as a source of well characterised quasi-monoenergetic neutrons. The measurement capabilities at both facilities, which are complementary, cover the whole energy range from a few meV to about 24 MeV. A Transnational Access project NUDAME has been running within the framework of the FP6 Euratom programme until March 31, 2008. This NUDAME project has proved to be successful with a high quality of research proposals and a large proportion of new users that were attracted. In total, 22 experiments were proposed, exceeding about 2.5 times the beam time which could be provided. 18 proposals were approved by the Programme Advisory Committee of NUDAME, but with a drastically reduced beam time. 90% of the supported users are first-time users. The large demand for experimental opportunities at the scientific infrastructure of IRMM shows clearly the need for support of scientific groups from the European Union. It is the objective of this proposal to offer for the next four years a total of 4500 hours of additional data-taking hours for external users. Experiments in the thematic area addressed in the 7th Euratom Fission Framework Programme can be performed provided that the experimental infras
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Smart Alloys Surface Patterning for Properties Tuning' (SASPAT).

assistant: **Concept**

The SASPAT project presents two main goals: (a) to train the talented young researcher Dr. Jose M. Porro, in the attractive growing field of Magnetic Shape Memory Alloys (MSMAs), where the host and partner institutions have developed their expertise and knowledge; and (b) the design, development and optimisation of smart patterned MSMA surfaces for applications in industrial sectors such as microfluidics and optical microswitching.The aim of the project is to exploit the effect of the martensitic transformation on the patterned MSMAs to fabricate tunable smart surfaces. The training program includes learning the processes for growing single crystals and epitaxial thin films made of MSMAs, the patterning of the surfaces using top-down and bottom-up lithography techniques, and the structural and magnetic characterization of the patterned surfaces to explore and optimize their optical response and wettability upon the application of the corresponding stimulus.During his short research career, the fellow has gained expertise in the field of nanomagnetism and patterned magnetic nanostructures, acquiring hands-on experience with several lithography techniques and both structural and magnetic characterization techniques. Nonetheless, to further boost his career, the fellow needs to broaden his knowledge in the field of magnetism, and within this project he will be able to acquire expertise in the field of MSMAs, as well as to complement the already known characterization techniques with new ones present at the BCMaterials and the partner institutions. Furthermore, the fellow will gain additional high-level training through two three-month secondments at the IMEM-CNR research institute in Parma, Italy, and at the Lappeenranta University of Technology, an industry-oriented teach
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Fuel Cell Hybrid Vehicle System Component Development' (HYSYS) targeting Sixth Framework.

assistant: **Abstract**

The objective of the project is the research on of low-cost components for fuel cell (FC-) systems and electric drive systems which can be used in future hybridised FC-vehicles (medium term objective) and ICE vehicles. The components will be analysed and tested in two FC-vehicle platforms with different concepts. The project consortium consists of 6 major European car manufacturers, 10 major and smaller suppliers, 6 institutes and 4 universities. The focus of the project is on components which have a high potential of significant cost reduction by decreasing complexity and/or choosing innovative approaches to support a future mass production. In the field of FC-system components the key components which are investigated are innovative air supply based on electrical turbochargers, novel humidification subsystems, new hydrogen sensors and innovative hydrogen injection system components. For the electric drive system we focus on highly integrated drive trains (converters, inverters and electrical motors) and high-energy-density battery systems based on innovative Li-Ion technology which has been developed in EU funded projects (EV-lift, Lionheart). All the component work is accompanied by a sub project which will work on requirements of the vehicles, subsystems and components, standardisation of the components, identification of synergies between components for FC- and ICE Hybrids, safety aspects and a comparative investigation of different electrical storage systems (battery / supercap) and the respective e-storage management. In the system level subproject not only will the components be integrated in the two validator vehicles and tested, but it will also be worked on optimised vehicle control strategies, energy-management and development of modular system control softw
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Identifying the mechanisms of phenotypic robustness using fluctuating asymmetry' (SymFish).

assistant: **Concept**

Phenotypic robustness, the capacity for organisms to buffer their development against internal and external perturbations, controls the strength of the links between phenotypes, genotypes, and environments. Despite its importance linking scales of biological organization, we have a poor understanding of how phenotypic robustness works—for example, the degree to which it is heritable, if the same mechanisms control both intrinsic and extrinsic robustness, or if it is correlated across organ systems. Working with Dr. Claudius Kratochwil in the Integrated Evolutionary Biology group at the University of Helsinki (UH), Finland, I will investigate the mechanisms of robustness using fluctuating asymmetry as an indicator of robustness. I will take advantage an ongoing hybrid cross of cichlid fishes in the lab, the offspring of which exhibit increasing rates of left-right color pattern asymmetry compared to their symmetrical parents. In research objective O1, I will identify the genomic basis of phenotypic robustness by selecting for increased and decreased color pattern asymmetry in this hybrid cross, and use whole genome sequencing to identify loci associated with decreased symmetry. In O2, I will test for gene-environment interactions in robustness by raising fish from asymmetrical and symmetrical populations at high and low temperatures and testing whether these populations exhibit different reaction norms. In O3, I will test whether robustness is correlated across organ systems by measuring asymmetry in other traits (paired fins, gills, jaws, eyes, and lateral line neuromasts) in the most and least asymmetrical fish from the cross. I will ask whether selecting for asymmetry in color patterns has also increased asymmetry in these traits.


**Keywords:** phenotypic robustness
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Testing mechanisms of species invasion in Galápagos: role of resource competition and species traits' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Biological invasions are the second most important threat to biodiversity, after habitat loss and habitat transformation. However, knowledge of the mechanisms underlying the success of species invasions is limited by the lack of information about the pre-invasion state of the community and the lack of experimental approaches to studying invader impacts. Considering that invasive species are driving native species extinctions and changing the functioning of ecosystems, modern experimental approaches are urgently needed to understand and to mitigate invasive species impacts. The Galápagos archipelago is renowned for its endemic species, yet this unique ecosystem is undergoing profound alterations as a result of plant and animal invasions, especially caused by the red quinine tree Cinchona pubescens. Cinchona was introduced to Santa Cruz Island and is now in the process of transforming the formerly treeless highlands into a forest habitat. Previous descriptive studies suggested that Cinchona had significant negative effects on species richness and cover and that it altered the microclimate. However, the mechanisms underlying these impacts are completely unknown since experimental manipulations have not been conducted. Therefore, the central objective of my study is to elucidate the ecological mechanisms that result in the extraordinary success of Cinchona pubescens as an invader. By forging a collaboration principally between scientists at Brown University, Technische Universität Berlin, Freie Universität Berlin, and the Technische Universität München, I will learn techniques in experimental ecology and molecular biology and apply to them to test mechanistic hypotheses about the impacts of Cinchona on the native vegetation of the Galapagos highlands and the role of symbiot
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'High Level eHealth Conference 2017', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The Maltese Presidency proposes to organise a High-Level Conference on eHealth in keeping with the practice established by first-semester Presidencies since 2007. The main objective will be to bring together high-level policymakers from all EU MS and other key stakeholders to discuss the most important current issues of common interest regarding the effective, safe and economic application of ICT to the planning, delivery and evaluation of health services. High-level delegates will be invited from all EU MS, Switzerland, Norway, Iceland & USA. The Presidency will co-locate the event with a Health IT conference & exhibition organised by HIMSS Europe. Partnering with HIMSS will help reach a wider and more diverse audience, including key stakeholders from the health IT industry, allowing EU eHealth policies and the outcome of relevant EU-funded research and innovation to reach a wider audience. The co-located events will be known collectively as “eHealth Week 2017” (EHW17).The EHW17 programme will be both diverse and comprehensive, highlighting developments taking place in various aspects of eHealth such as legal, organisational, semantic and technical. The overarching theme of EHW17 is “Data for Health: the key to personalised sustainable care”. Subjects discussed will include:-Patient access to and sharing of health data-Moving health data safely onto cloud infrastructure-Sharing personal health data across country borders-Improving effectiveness, safety and privacy of mHealth-Scaling up digital innovation for health and care-International cooperation in eHealth-Smart environments & integrated care-Data management and analytics for personalised medicine & public health policyEHW17 will include an Informal Working Lunch for high-level delegates, during which they will be