RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Application of advanced methodologies for the analysis of protein oxidation in muscle foods' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The oxidation of food lipids has been profusely studied for decades whereas oxidized proteins have remained in the background. Nowadays, protein oxidation is a hot topic of increasing interest amongst food researchers because of the relevant and scientifically sound results derived from recent studies, including a previous EU-project (EIF Marie Curie; Pox-MUSCLE). Our studies in model systems contributed to understand the susceptibility of food proteins, and particularly, myofibrillar proteins to oxidation, the precise mechanisms and pathways involved in protein oxidation and the interaction with oxidizing lipids. We originally identified particular protein oxidation products derived from the oxidation of food proteins and investigated the interactions of myofibrillar proteins with plant phenolics. Nevertheless, the fate of oxidizing proteins and amino acids during food processing and storage is still poorly understood. Advanced methodologies are required to deepen the knowledge of protein oxidation and fulfil the upcoming challenges. In collaboration with the University of Helsinki, we developed novel and advanced methods for assessing oxidation of food proteins (Fluorescence spectroscopy and LC-MS). The purpose of the present project is to apply the skills and knowledge gained during the last 2 years to study protein oxidation in real meat products. Study the influence of processing and storage on oxidation events and the effect of protein oxidation in nutritional and technological aspects of muscle foods of interest for the meat industry will be the main concerns of this project. The development of efficient antioxidant strategies and particularly, the use of natural antioxidants (plant phenolics) will be also addressed. By funding this proposal, the EU-commission wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Illusions of eternity: the Constitution as a lieu de mémoire and the problem of collective remembrance in the WesteRn Balkans' (We-R), addressing dissemination and exploitation.

assistant: **Impact**

We-R focuses on the important relationship between collective memory and national identity by introducing a ground-braking perspective: the study of the Constitution as a lieu de mémoire. We-R’s aims are to understand how and to what extent contemporary Constitutions may be used as tools for bringing the past in the present, and analyze the ways in which configurations of memory and identity through the Basic Law of the Land can obstruct reconciliation and democratization processes in culturally heterogeneous societies. In addressing this topic, the researcher will use the Western Balkans (including Slovenia, Croatia, Bosnia-Herzegovina, Serbia, Montenegro, Macedonia, and Kosovo) as case studies and an innovative interdisciplinary perspective which will integrate in comparative constitutional law memory studies and nationalism studies, as well as a multi method approach that combines comparative analysis with critical political discourse analysis and social media research. The proposed mobility plan will allow the researcher’s training at CU to reinforce her knowledge in Balkan studies and acquire new methodological skills, and the residence at Eurac to elaborate the first existing “Practical Guidelines of Democratic Memory Construction” (DeMeCon). Given the importance of its objectives We-R is potentially entitled to become a reference model for other comparable case studies. The action will let the researcher benefit from interactions with an international network of excellence composed of scholars in various fields, international and national policy-makers and watchdog organizations. We-R comes appropriately timed, in a moment in which nationalism and historical revisionism are growing in Europe and beyond and are threating the future of the EU project.


**Keywords:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The 6th Barcelona Logic Meeting' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

The topic of the event is Mathematical Logic. It concentrates mainly on three areas: Algebraic Logic, Model Theory and Set Theory, although it encompasses all areas in the field, including Proof Theory, Recursion Theory, Computational Logic and Complexity Theory, as well as their applications to other areas of Mathematics and Computer Science.It will be a three-day international conference at the highest scientific level, with the following aims:- To offer leading experts in the field a suitable place for announcing their latest research results to a broader audience;- To help bridge the gaps between several distinct, although closely related, areas in Mathematical Logic, through survey talks by renowed speakers;- To provide young logicians with an opportunity for presenting their results to leading researchers in their respective fields, and for interacting with them through informal discussions.The scientific program of the meeting will consist on:- 8 invited lectures;- 30 short communications;- 2 informal discussion sessions open to all participants. The conference will be a satellite activity of the 3rd European Congress of Mathematics, which will not only increase the participation of mathematicians from other related areas, but it will also secure the presence of Mathematical Logic in the whole series of events organized around the 3ECM.ftp://ftp.cordis.lu/pub/improving/docs/HPCF-1999-00058-1.pdf
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Pan-European Network for Neuroscience Research Infrastructure and Strengthening of Support capacities' in the context of a Horizon Europe call.

assistant: **Objectives**

Current challenges in European Research and Innovation (R&I) infrastructure in neuroscience include barriers for collaboration, funding gaps, undeveloped skills, or lack of alignment in R&I policies. PANERIS consortium aims to be more effective together by i) ensuring access to a wider pool of European talent to neuroscience-related infrastructure and ii) contributing to the alignment of their R&I strategies, policies and funding programs at institutional, regional and national level. Access to excellent neuroscience infrastructure and resources will be maximised through capacity building, tackling key skills, and setting a common internationalisation strategy among the participating entities. Three widening entities and one non-widening will promote knowledge exchange among early-stage researchers while addressing issues like research administration, communication, ethics, human resources, technological transfer or open science, among others. Moreover, interaction with key R&I networks will not only increase the global proficiency of consortium members but will also contribute to engage with regional and national authorities for the creation of valuable synergies in funding programs and policies. Overall, PANERIS will consolidate borderless R&I strategies in neuroscience, contributing to the free flow of knowledge and technology in the European Research Area.


**Keywords:** Neurodevelopment, Ageing, Obesity, Addiction, Synergy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Decoding and designing biomolecular systems with hybrid DNA:RNA: protein nanotechnology'.

assistant: **Objectives**

In recent years, we have witnessed the emergence of DNA nanotechnology that enables self-assembly of some of the largest and most complex functional molecular systems to date. Simultaneously, RNA plays a pivotal role in nanomedical advancements, notably in the development of Covid-19 vaccines. Moreover, utilising deep learning to address the protein prediction challenge paves the way for de novo protein design in the realm of protein nanotechnology. BioHYBRITE is designed as an innovative and pioneering training network, with the unique vision of developing the next-generation of biomolecular systems based on integrated hybrid DNA:RNA:Protein nanotechnology. BioHYBRITE brings together leading European research groups for combining all sequence-based biomolecules into a unified bottom-up nanobiotechnology. The consortium will collectively build modular platforms with a range of novel functions for molecular sensing, information processing and actuation. Thereby the collaboration synergizes a unique toolset of theoretical and experimental methods for designing and understanding the hybrid systems including state-of-the-art single-molecule and superresolution technology. The outcome will be a new generation of young experts in the development of smart, self-assembling, hybrid nano-devices that detect and act in complex biomolecular systems and will form the basis of a future nanomedicine based on active molecular systems. The doctoral candidates will be trained in all aspects for programmed design of hybrid bottom-up nanostructures, their characterization and use for decoding and interacting with biomolecular systems, thereby fully benefiting from the synergies of the different partners’ competences. The innovative and applied focus is supported by the involvement of pione
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Sense, Science & the Magics of the Planet Pantry' in the context of a Horizon 2020 call.

assistant: **Objectives**

SESAM21 NIGHT will through a thematic approach bring research closer to the general public and pursue 3 main objectives: 1. enhance understanding of the impact of researchers’ work on citizens‘ daily life; 2. encourage young people to embark on a research career; and 3. counteract stereotypes about the work of researchers. We will i) use the research challenges created by the climate crisis in relation to nature, environment and food & agriculture as overall theme to create understanding of the impact of research and innovation on citizens’ life.  ii) pay particular attention to the role of young people and use the school as an arena that can reach the wider community and citizens. iii) create a prime platform to increase recognition of researchers’ work and create an excellent opportunity to encourage young people to embark on research careers. iii) put particular emphasis on the challenge related to protecting nature in both its wild and cultivated form when it comes to feeding the world in a sustainable way. We use outdoor learning and Nature Based Education as the didactical foundation. The planning & preparation phase is at 6 schools across Denmark. Execution however, is split in a on-school and off-school part. We use the school to execute the NIGHT as an In-House and Open-School event. Friday morning is In-House for all pupils, Friday afternoon is Open house for parents, families, friends & local community. Saturday we leave the school and move to “the town”. Two major attractions - the CPH  Experimentarium and the Foodcamp Højer in the southest – will act as venues. Experimentarium is well known for its research communication and is a leading science centre with 30 years of experience and > 400.000 visitors/year. Højer Food camp is a newly established venue for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Ku-Band Satellite Receiver' (KuRx) targeting Horizon 2020.

assistant: **Abstract**

The objective of the feasibility study is to explore and assess the technical feasibility, and the commercial potential of the company's, award-winning and highly-disruptive invention: a novel Ku-band receiver for space applications. For the first time, the innovation will allow satellites to directly process signals up to 18 GHz completely removing the need for any traditional, analogue, RF down-conversion. This represents a profound advance for electronic engineering and satellite communications!The expected outcome is that the company will have elaborated a commercial strategy for formally productising and bringing to market its innovation, e.g. assembly, test, branding, sales and marketing.  The proposed innovation solves the following problems:Today, the satellite industry is handicapped by the inflexibility, complexity, power consumption and cost of  traditional, analogue RF down-conversion, with each stage costing €160k. For key European suppliers of satellites, conventional receiver designs are adding over €8M to the cost of each European payload.The current approach to satellite design requires the design of existing receiver technology to be changed for almost every new mission adding unnecessary, non-recurring re-design and re-qualification costs and effort to key European programs. These disadvantages severely handicap European space companies when competing for global satellite tenders. Today, the majority of satellite communication occurs at L/S & C-band, however, these frequencies have become congested and both the space industry, European governments and European space agencies are looking to Ku-band to provide operators the bandwidths needed to deliver tomorrow's, space-enabled economy for everyone. Spacecraft operators are constantly complaining that t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Recombinant vaccines against infectious pancreatic necrosis (IPN) in salmonid fish', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Our five-partner consortium (FAIR CT-95-0353) is concerned with developing recombinant DNA vaccines for Infectious Pancreatic Necrosis (IPN). IPN is now recognised as the most serious problem in salmonid farming in Norway and affects both juvenile and post-smolt fish. Recent estimates of losses due to IPN disease are circa 54 Million ECU per annum. A major part of our research initiative is the development of nucleic acid vaccines against IPN. To date, this has focused on the use of naked DNA constructs and packaged RNA viral particles harbouring the IPN VP2 gene. The VP2 gene product is known to be a protective antigen and the world's first recombinant subunit fish vaccine based on this protein purified from Escherichia coli has recently entered the market place. However, there is considerable evidence that conformational epitopes are important in protection and thus, a bacterial product is unlikely to adopt the correctly folded structure. Nucleic acid vaccination circumvents this problem as the protein is made and folded in its natural host cellular environment. DNA vaccination is now emerging as an exciting technology in fish vaccine research. Several groups have shown that the Cytomegalovirus (CMV) immediate early promoter works very efficiently when injected into fish muscle. As in other biological systems, injected DNA persists in the muscle tissue for a considerable time where it can stimulate extended antigen synthesis. It appears to exist as an episomal plasmid and does not integrate in the host genome. We have made recombinant plasmids harbouring the VP2 gene under the control of the CMV promoter and have tested their ability to express VP2 in cell culture. These plasmids have also been injected into fish muscle and expression and immunological analyses are on
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'POLYBOOST: Renovating the Polyclonal Immunotherapy' (POLYBOOST).

assistant: **Innovation**

Immunotherapy is an essential field of medicine that allows clinicians to stimulate or to suppress the response of our immune system against specific stimuli. The progressive ageing of the population and the rising incidence of chronic diseases is driving the demand for immunotherapy, as it can be used to fight cancer or autoimmune diseases. One of its major applications today is to prevent the rejection of transplanted organs. Since organs are scarce (+40,000 Europeans on waiting list), patients are administered high doses of polyclonal immunosuppressants for several days around the time of surgery to prevent rejection. However, current polyclonals are not safe or reliable. Patients respond to these products by developing severe side effects that increase the risk for death & the medical costs. Thus, current polyclonals are only open for one time use. Also, the transplanted organ is severely damaged in the process, reducing its life-survival. In response, the consortium XENOTHERA & AVANTEA has created this project with the main objective of bringing to market a unique platform for the production of safer polyclonals (POLYBOOST). Our innovative method will revolutionize the field of immunotherapy, since it enables production of customized polyclonal products of low antigenicity, which retain a full immunological effect but do not induce side effects. We have proven the efficiency of POLYBOOST by customizing a polyclonal for transplantation medicine. In views of this successful achievement, we now aim to move forward towards the market. Thus, in Phase 1 we plan to assess all the aspects influencing the project from the technical, commercial and financial perspectives. We believe POLYBOOST will bring huge benefits for society and medicine, entering the market with a so lo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Revealing novel molecular mechanisms linking DNA replication and cell fate decisions' (RepDiff) targeting Horizon 2020.

assistant: **Abstract**

All cells in our body share the same genetic information. Cellular identity is determined by epigenetic mechanisms, which control gene expression. Replicating cells should accurately replicate their DNA sequence and copy their epigenetic profile to maintain their identity. DNA replication entails the disruption of the chromatin organization ahead of the replication fork and its restoration behind it. When cells change their identity in either normal development or abnormal processes as cancer, they undergo epigenetic reconfiguration, which defines their new identity. Recent works have revealed a time gap between DNA replication and epigenetic state restoration of many chromatin regulation layers. I hypothesize that the time until chromatin restoration post DNA replication provides a ‘window of opportunity’ for transcription factors and chromatin regulators to bind otherwise inaccessible areas and to facilitate chromatin reconfiguration and that pluripotent cells have specialized chromatin replication proteins, which preserve their high epigenetic plasticity. To test this hypothesis, I will join the lab of Prof. Anja Groth, a leading expert in the mechanisms controlling chromatin replication. Together with my expertise in stem cells and reprogramming, I will address this question with two sequential steps. I will use a cutting edge, quantitative proteomics method in which nascent DNA is affinity purified and its associated proteins are analyzed by mass-spectrometry (NCC-SILAC). I will use this discovery tool to define the proteins dynamically associated with nascent chromatin in pluripotent cells and cells that undergo cell fate transitions. I will then investigate proteins predicted to effect chromatin restoration/reconfiguration to dissect their functional role. This w