RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Unravelling the molecular basis of common complex human disorders using the dog as a model system' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Despite major efforts, identifying susceptibility genes for common human diseases - cancer, cardiovascular, inflammatory and neurological disorders - is difficult due to the complexity of the underlying causes.  The dog population is composed of ~ 400 purebred breeds; each one is a genetic isolate with unique characteristics resulting from persistent selection for desired attributes or from genetic drift / inbreeding. Dogs tend to suffer from the same range of diseases than human but the genetic complexity of these diseases within a breed is reduced as a consequence of the genetic drift and – due to long-range linkage disequilibrium – the number of SNP markers needed to perform whole genome scans is divided by at least ten.  Here, we propose a European effort gathering experts in genomics to take advantage of this extraordinary genetic model.  Veterinary clinics from 12 European countries will collect DNA samples from large cohorts of dogs suffering from a range of thoroughly defined diseases of relevance to human health. Once these different cohorts will be built, DNA samples will be sent to a centralized, high-throughput SNP genotyping facility.  The SNP genotypes will be stored in central database and made available to participating collaborating centres, who will analyze the data with the support of dedicated statistical genetics platforms. Following genome wide association and fine-mapping candidate genes will be followed up at the molecular level by expert animal and human genomics centers. This innovative approach using the dog model will ultimately provide insights into the pathogenesis of common human diseases – its primary goal.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Continual and Sequential Learning for Artificial Intelligence' to be submitted under Horizon Europe.

assistant: **Abstract**

Machine Learning systems, while promising, lack the autonomy needed for many real-world applications beyond mere proof-of-concept stages. The key challenge lies in enabling AI to continuously adapt to shifting data distributions and proactively seek information under high uncertainty.Fields such as drug discovery and micro-chemistry are expecting breakthroughs from AI, given the vast and intricate search spaces they deal with, coupled with expensive data acquisition. It is vital for algorithms to steer this search, assimilate new data, and strategically explore promising zones.Reinforcement Learning (RL) offers tools and methods for agents to autonomously learn from their actions, but its efficacy has been largely confined to stationary, single-task settings. ConSequentIAL's vision is a Continual and Sequential Learning AI that marries supervised and unsupervised learning with advanced data gathering and RL-driven discovery mechanisms. To achieve these goals, I propose to bridge the theory of constrained and non-stationary RL to build a sound and useful mathematical formulation of the problem. On these new solid grounds, I develop novel algorithmic principles that allow the agent to detect and respond to external shifts, while remaining aware of her own impact on the system she interacts with. I address the memory-versus-stability trade-off central to continual learning by enabling agents to actively plan their skill acquisition in accordance with their long-term goals. The ambition of this project is to position AI to tackle the consequential scientific challenges ahead.


**Keywords:** Reinforcement Learning, Learning Theory, Continual Learning, Lifelong Learning
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'BiogasAction: Promotion of sustainable biogas production in EU' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

BiogasAction aim to serve as vehicle for the development of the European biogas sector and thereby contribute to the EU 2020 targets by focusing on removing non-technical barriers to widespread production of biogas/biomethane from manure and other waste. Central driver is the cooperation between different policy levels at EU, national and regional level. The project will boost biogas development in the target regions in conjunction with replication efforts & promotion at broad EU scale. BiogasAction key activity & expected impact:• A web portal containing EU-wide biogas market overview, technical biogas and biomethane information and experience of EU/national biogas projects, case studies and free on-line/off-line biogas tools• Biogas and biomethane intervention strategy plans in the 9 target regions• Replication of the project in 5 EU countries/regions • A guidance document for investors about financing biogas/biomethane project and reducing investment risk. • A guidance document for policy and decision makers and for local authorities/municipalities, to enable them to improve national framework conditions for biogas and biomethane deployment• Definition and support of a total of 50 high quality, sustainable biogas projects in the 9 target regions. • 3 peer learning European workshops focusing on key competence areas (80 participants), 1 European roundtable about advanced biogas applications, organisation of at least 1 national energy info day in each target region, with more than 100 participants/event• 3-4 events/training courses per target region for public administration aimed to improve the framework, including follow-up of the recommendations• 2-4 events/training courses per target region aimed to raise the public acceptance• A local training package incl. use of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Data Analytics, Data Sources, and Architecture for Upgraded European Customs Risk Management' under Horizon 2020.

assistant: **Concept**

Security and fraud in cross-border trade and supply chains are key priorities for the EU customs administrations due to the increasing risk of transnational crime and terrorism and the e-commerce-driven growth of customs declarations. Hence, EU customs administrations have to rapidly increase their capability to search for more accurate data sources to better assess these risks and increase their inspection hit rate. To address this challenge, PROFILE seeks to accelerate the uptake of state-of-the-art data analytics and incorporation of new data sources for more effective and efficient European customs risk management. The project provides tailored solutions, that build on modern methods in machine learning, graph-based analytics, and natural language processing, to help targeting officers and strategic analysts to collect and organise unstructured data, data-mine large datasets, apply semi-supervised machine learning that utilises feedback of control results, and to visualize complex data sets. PROFILE enables customs-to-customs systematic sharing of Entry Summary Declarations and other risk-relevant information through the EU-wide PROFILE Risk Data Sharing Architecture (RDSA). The project also connects national customs risk management systems to logistics Big Data of INTTRA and the Universal Postal Union (UPU) and provides customs an improved access to online data, especially valuation-relevant data of e-commerce sites. PROFILE also strengthens cooperation and data exchange among customs and other competent authorities. Better access to data, customised state-of-the-art data analytics, and stronger cooperation will provide the customs an enhanced 360º view on cross-border cargo flows. With PROFILE solutions, customs administration can increase substantially the hit ra
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Responsible Research and Innovation in Practice' (RRI-Practice).

assistant: **Concept**

The RRI-Practice project will bring together a unique group of international experts in RRI to understand the barriers and drivers to the successful implementation of RRI both in European and global contexts; to promote reflection on organisational structures and cultures of research conducting and research funding organisations; and to identify and support best practices to facilitate the uptake of RRI in organisations and research programmes. The project will review RRI related work in 22 research conducting and research funding organisations and will develop RRI Outlooks outlining RRI objectives, targets and indicators for each organisation. It will involve comparative analysis of the five EC keys of RRI locating these within broader, evolving discourses on RRI. Within each identified RRI dimension the project will analyse how the topic has developed in particular social and institutional contexts, how the RRI concept and configuration meshes, overlaps and challenges existing organisational practices and cultures, leading to an analysis of the barriers and drivers associated with operationalising and implementing RRI. 12 national case studies will allow for in depth studies of, and dialogue with, the included organisations, and will form the basis for systematic analysis and comparison of drivers, barriers and best practices on each dimension of RRI. The project design also allows analysis of such drivers, barriers and best practices related to national and organisational characteristics, safeguarding the need to take into account diversity and pluralism in regional RRI programs. These analyses will ultimately end up in recommendations to the EC about effective, efficient and targeted strategies for increasing RRI uptake in different kinds of organisations and nation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Biologging to inform Prevention of Seabird Bycatch'.

assistant: **Innovation**

As the global footprint of fisheries increases to match market demands, interactions between seabirds and vessels become more frequent leading to scavenging opportunities for many species, but also increase bycatch risk. Many seabird populations are in rapid decline, and bycatch in fishing gears has been identified as a leading cause.BioPSy is a  global project, where the candidate will develop skills pertinent to seabird bycatch prevention in New Zealand, a country with an internationally recognised track record in applied conservation and seabird bycatch management. On the return phase, these skills will be applied to areas of Europe with severe seabird bycatch issues and little to no legislated corrective measures. Cutting-edge analyses will be developed and applied to seabird biologging data to design effective seabird bycatch prevention measures (SBPMs). BioPSy relies on stakeholder engagement for experimental design, with engagement skills and implementation focal point of the training program.New Zealand’s open fisheries practices and extensive observer data will be reviewed for SBPMs used, bycatch rates per hooks set, and efficacy of current SBPMs then estimated. Individuals of at-risk seabird species will be tagged with biotelemetry devices that record depth, location, and acceleration when at sea. This will reveal behaviour around vessels in the presence/absence of SBPMs, how deep birds dive to scavenge, and how this interacts with light availability. These behaviours will be placed in the context of current SBPM efficacy, and recommendations to improve SBPMs communicated to key stakeholders.The candidate will bring insights gained in New Zealand back to Europe, where observer coverage of fisheries most prone to seabird bycatch is minimal. The transferability
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'US and THEM or the EU and the US; a comparative analysis of US and EU environmental law and policy approaches to global environmental problems' in the context of a Sixth Framework call.

assistant: **Objectives**

The protection of the environment is one of the key challenges facing the international community in the 21s apos; century. The US and EU, two of the major international actors, have successfully worked together to deal with major environmental problems. H owever, in the past few years, there seems to be an increasing lack of dialogue and understanding on environmental issues between the two sides of the Atlantic. Different views and approaches on, inter alia, climate change and biotechnology have contribute d to the creation of an atmosphere of confrontation between the US and the EU. Such divisions on environmental problems may lead to conflicts in other areas, for example trade, and consequently to the further deterioration o f a fundamental alliance and pa rtnership. Moreover, this is a Iready 1 eading toa failure to properly tackle global environmental problems. The research will analyse the policies and legal instruments adopted at the international level, in the US and in the EU to deal with global enviro nmental problems, in particular climate change and biodiversity (focusing on the issue of genetically modified organisms and biotechnology). The research will concentrate on the approaches and differences between the US and the EU on such issues. It will b e conducted by an initial review and analysis of existing literature, followed by in depth interviews with policy-makers, legislators and stakeholders on both sides of the Atlantic. The research apos;s output will consist of several publications in leading refereed journals, the publication of a monograph, the participation in international conferences and presentations to government officials and civil servants in the US and in EU. Better knowledge of the US position should hopefully lead to a better infor me
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Unravelling unsteady fluid flows in porous media with 3D X-ray micro-velocimetry' in the context of a Horizon Europe call.

assistant: **Objectives**

Models of fluid flows in porous materials commonly fall short because they fail to capture the effects of the puzzling underlying microscopic dynamics. These flows are very common: examples range from groundwater flow and H2 storage in underground rocks to water discharge in fuel cells. The fluctuating, microscopic dynamics are poorly understood because they have so far been inaccessible in the 3D labyrinths formed by pore geometries, hampered by the optical opacity of the materials. In FLOWSCOPY, I will cause a paradigm shift by resolving this inaccessibility, enabling the measurement of unsteady 3D flows inside opaque porous materials. First, I will enable the inspection of flow fields in all their µm-scale complexity by creating a method that tracks tracer particles flowing through the pores with 3D X-ray imaging. To achieve the required millisecond imaging times - up to 3 orders of magnitude faster than my state-of-the-art preliminary results – the new approach will retrieve tracer locations in each of the many radiographs that conventionally make up a single tomographic time frame. Then, I will untangle the upscaling problem, building the first method that can measure flow maps averaged on a sliding scale from nano- to centimetres. Finally, I will apply the methods’ transformative capabilities to two pertinent problems in arguably some of the most complex porous media: geological materials. First, I will investigate how two fluids, such as water and H2, displace each other in porous rocks, lifting the veil on capillary fluctuations that deviate from current models. Second, I will unriddle flows of viscoelastic fluids, such as those to clean up polluted sediments, which exhibit a poorly understood transition from steady to chaotic dynamics. Beyond this, the new tech
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Next Generation HIV-1 Immunogens inducing broadly reactive Neutralising antibodies' (NGIN).

assistant: **Concept**

The elicitation of broadly neutralising antibodies (Nab) remains the primary and most challenging goal in HIV-1 vaccine development. Although a few anti-HIV-1 monoclonal antibodies with broadly neutralising capability have been isolated from infected individuals, none of the immunization strategies thus far explored has proven effective in inducing similar antibodies. Objective of this application is the development of a variety of ‘next-generation’ HIV-1 envelope-based immunogens that in combination with new adjuvant formulations are capable of eliciting high-titer broadly Nab responses. Our strategy will be based on one side on the identification and cloning of envelopes that have successfully elicited broad Nabs in their natural hosts, focusing on HIV-1 strains derived from patients with high-titered broad Nabs in their sera; on the other side, we will introduce rational modifications into these and promising HIV-env based immunogens that are already under development by NGIN’s partners, with the aim of exposing cryptic conserved neutralization epitopes and permitting their efficient presentation to the immune system. HIV-1 envelopes will be expressed in viral vectors or as trimeric (gp150) soluble proteins and screened for their immunogenicity and antigenicity in rabbits. A selection of envelopes with highest antigenicity will be expressed as trimeric envelope-complexes on the surface of virosomes or virus-like particles (VLP), to further improve immunogenicity. New immunogens will be evaluated in prime-boost regimens in rabbits using novel effective adjuvant formulations. Immunogen/adjuvant combinations that prove most effective in eliciting broadly Nabs both systemically and at the mucosal level will be evaluated in non-human primates for their immunogenicity and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'The energy efficient ship'.

assistant: **Objectives**

The industrial objective of this proposal is to participate in systems identification, modelling, optimization and validation for the energy-environment system in transport - in particular ships for inland waterways and shortsea traffic. The state of the art considers only energy consumption and thus savings potential in the ship's operational life. Little attention has been focussed on a suitable model framework to aid in construction of the vessels - in particular embodied energy - energy consumed in extracting and fabricating the components for the ship and joining the parts together into a ship, and later for the scrapping of the ship. Two very excellent opportunities exist for walidation activities in real-life industrial planning environnent: Diesel-electric propulsion, comparing the embodied energy in cheap high-speed to expensive medium speed engines, and the bulk transport of cement with either cheap pneumatic/expensive mechanical loading/unload.