RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'The value of non invasive investigations in the identification of individuals with Asymptomatic Carotid Stenosis at Risk of Stroke', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The objectives of the proposed project are:(a) the identification of a subgroup of patients with asymptomatic carotid stenosis at risk of ipsilateral stroke greater than 4% p.a.;(b) the identification of a subgroup of patients with a risk of ipsilateral stroke less than 1% p.a., and(c) the identification and standardisation of non-invasive tests or combinations of such tests and appropriate criteria that can achieve (a) and (b).For the first time there is evidence that carotid endarterectomy in patients with asymptomatic carotid stenosis will reduce the incidence of stroke. However, one may need to operate on at least 20 patients to prevent one stroke in 5 years or 100 patients to prevent one stroke in one year. This means that one is operating unnecessarily on a large number of patients. What is needed is to identify those who are at high risk (>4% stroke incidence p.a.) Even more important is to identify those who are at low risk (>1% p.a.) and spare them from an unnecessary operation which carries an inherent mortality and morbidity risk. The objectives of the project will be achieved by reinforced concertation. It is proposed that patients with asymptomatic carotid stenosis greater than 50% will be entered into the study from different centres, and a number of non-invasive tests will be performed in order to determine the degree of stenosis, the presence of ulceration, plaque characterisation, presence of silent infarcts on CT-brain scans and cerebral reactivity to hypercapnia. Patients will be followed up for three years with the main endpoint being stroke. Training, quality control and software will be provided by the Co-ordinating Centre. The contribution of such a study will be the establishment of standardised methodology that can be used eventually not only by
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Components for use in renewable energy systems' to be submitted under Fourth Framework.

assistant: **Abstract**

Objectives The project aims at designing, modelling and testing facade and ceiling components to be used for construction or retrofitting of office buildings with good appearance and durability qualities. They must also be able to be produced in industrial scale at minimum cost and provide comfort with significant reduction of energy consumption. Technical Approach The project involves the combination of passive components such as fixed sunscreens (which act as barriers for solar energy) or diffusing reflectors, and of active components such as panels or window glazing absorbing the solar radiation and providing heat drawn off from the facade to power a chiller, and chilled ceilings used to control the inside temperature. As the facade of a current office building is widely open to the visible and infrared sun radiation, it is important to design functional screens which do not cause glare problems but can reflect or dissipate part of the solar energy. These sunscreens will be designed as open core composite panels in order to optimize the different modes of heat dissipation such as reflexion, absorption, radiation and convection. A complementary active system will also be designed in order to absorb another part of this solar radiation by means of a fluidized glazing in order to provide the power source for an absorption cooler delivering a sufficient amount of chilled fluid. The cooling exchange will take place by means of chilled ceilings which will include:  high reflectivity light diffusing elements for visual comfort in the office structure,  infrared energy absorbing elements acting as cooling surfaces. Expected Achievements and Exploitation The outputs of the project will be:  a complete model describing the performances of the system in connection with the char
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Smart phononic crystals for aircraft noise reduction' in the context of a Horizon 2020 call.

assistant: **Objectives**

Nowadays air transport is a vital means of integration, cohesion and economic development amongst European members. However, due to the incessant growth of the global air traffic, aircraft noise pollution has gradually become a major public issue. Thus, European Union is strongly addressing its aviation industry towards a more competitive and sustainable system. HARPOCRATES perfectly shares this current international trend and aims to develop a new-generation sound insulation system to attenuate aircraft noise emissions, in accordance to the EU noise transport policy which over the coming years will require more and more quiet operating vehicles. HARPOCRATES proposes to achieve such a technological breakthrough manipulating sound waves via phononic crystals (PCs), i.e. artificial materials ideally suited for realizing efficient filters or insulators. In fact, the project intends to exploit PCs to proficiently control elastic waves via the so-called pass bands (PBs) and band gaps (BGs), which permit and inhibit, respectively, the waves to propagate within precise frequency ranges. Specifically, proposal objectives provide the design, optimization and experimental validation of the engineered innovative device, promoting theoretical and experimental evidences capable to move aircraft noise reduction expertise towards new horizons.The fully accomplishment of the project objectives will speed up a technological breakthrough development in the framework of aircraft noise emissions, enhancing and maximizing its contribution to the European knowledge-based economy and society. In addition, HARPOCRATES allows the applicant to fully develop his potential thanks to an ad-hoc specialized and advanced training provided to the candidate in the course of the project. Proposal permits
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Coordination Action on the Aetiology, pathology and prediction of type 1 diabetes in Europe' (TONECA) targeting Sixth Framework.

assistant: **Abstract**

Type 1 diabetes mellitus (T1DM) imposes a heavy burden of morbidity and premature death on more than 2 million inhabitants in Europe. To identify new targets for prevention, diagnosis and treatment of type 1 diabetes mellitus (T1DM) greater understanding of the aetiology and pathology of T1DM is crucial. This requires the elucidation of the cellular and molecular mechanisms responsible for T1DM through bringing together leading European centres of expertise in the field of clinical and experimental T1DM research. The capabilities of the European groups participating in this Coordination Action (CA) provide the required technical skills and innovative advances. European diabetes research expertise in T1DM as assembled in this CA proposal will enable the coordination of RTD projects, which are already in receipt of funding for the research part. The research topics to be coordinated in this CA deal with a) molecular mechanisms of beta cell death and signalling pathways of apoptosis in T1DM b) the impact of environmental factors upon the genetically based regulation and progression of T1DM c) the use of established and new animal models to unravel the molecular mechanisms of the aetiology and pathology of T1DM d) the role of the cellular immune system in the pathogenesis of T1DM. The financial support for this CA will allow the running of the coordination activities. The workplan comprises eight workpackages (WPs). Four WPs deal with the specific CA co-ordination activities, directed towards the four major scientific objectives of the research to be coordinated. Three WPs deal with the overall CA co-ordination activities and one WP comprises the CA management activities. This will make it possible to detect the underlying causes of T1DM with the aim of identifying targets
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Imaging and detection of tumor-associated glycan structures on tumor cells'.

assistant: **Objectives**

The overall objective of Glyco Imaging is to develop novel assays for detection of glycans as biomarkers associated with aggressive and metastatic cancer forms. The assays will be developed for biomarker detection in blood, urine, cells and tissue. Molecularly Imprinted Polymers (MIPs), or plastic antibodies, have been developed for targeting the human glycan sialic acid (SA), or Neu5Ac. The efficiency of the Neu5Ac specific SAMIPs targeted to the biomarker SA in different solvents (methanol, water, phosphate buffer) will be exploited. The non-human Neu5Gc, which is incorporated into human glycoconjugates through dietary sources such as red meat, and shown to be involved in malignant cell transformation in humans, will also be investigated by using highly specific Neu5Gc-SAMIPs. The imaging and detection techniques used will be based on fluorescence, 3D-viewing of cancer cells by digital holographic microscopy and magnetic separation columns.The results in this research  consortium will lead to major technological advances having impact on 1) health care, since it will develop more accurate and reliable diagnostics of aggressive and metastatic cancers, 2) drug discovery allowing a faster and cheaper biomarker targeting and detection; and 3) biochemistry research laboratories in resulting in improved understanding of glycan expression in cancer, with emphasis on aggressive metastatic cancer. The training of researchers will be performed by a consortium consisting of 6 partners with biomedical, imaging and particle synthesis skills (4 groups, one institution, one technology company). This forms the basis for a very competent interdisciplinary training program with high quality in both education and research. 8 early stage researchers (ESRs) working on specific tasks withi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Ultrahigh resolution NMR tools for chemistry and structural biology' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Solution NMR spectroscopy is among the most important techniques in natural science, particularly for structural biology and organic chemistry research. Spectral resolution and sensitivity are the key parameters controlling access to structural information at the atomic level; at present it is resolution that limits the complexity of structural problem, whether chemical or biological, that NMR can be applied to. Multidimensional NMR has allowed huge strides to be made in studies of the 3D structure and dynamics of complex molecules, but in each dimension the multiplet structure caused by homonuclear couplings sets the resolution limit. Very recently, an improvement to one of the most widely-used and prototypical techniques, the HSQC experiment, has been published by the NMR methodology group at Manchester University headed by Gareth Morris and Mathias Nilsson. This uses for the first time suppression of homonuclear proton-proton couplings in real time during HSQC data acquisition, and results in a simultaneous improvement of a factor of two or more in both resolution and sensitivity, marking a significant breakthrough. Initial results confirm that the basic approach is viable in macromolecular systems, including proteins. Similar approaches should be applicable to a wide range of multidimensional techniques, and have the potential to increase significantly the structure-determining power of NMR. This project sets out plans for the development of a range of novel real-time acquisition methods, including for example improved 3D triple-resonance pulse sequences for protein backbone assignment, and exploiting synergies between real-time homonuclear decoupling and non-uniform data sampling methods to maximise the efficiency of structural studies of complex systems by NMR.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'A Precipitationshed Approach to Changing Extremes' in the context of a Horizon Europe call.

assistant: **Objectives**

Characterizing the frequency of future precipitation extremes is a fundamental task in order to understand and mitigate their effects under future climate conditions. However, predicting these changes is a challenging task as intense rainfall is poorly represented in climate models, and extrapolations based on historical data are highly uncertain. The objective of the PACE project is bridging this disconnection by developing an innovative physically-informed statistical model for rainfall extremes. The proposed methodology explicitly accounts for the interannual variability of atmospheric moisture fluxes and their future predicted changes. PACE will achieve this objective by using an innovative precipitationshed perspective. Precipitationsheds - the regions of Earth from which most precipitable water originates before reaching a target site  will be computed using a moisture tracking technique. By including in the statistical representation of rainfall extreme key physical information integrated over a precipitationshed, PACE will provide a novel representation of how dynamic and thermodynamic changing conditions in upwind areas affect the frequency and probability distribution of downwind precipitation. By learning rainfall statistical properties from historical data and relying on climate model predictions only for large scale climate features, the PACE action will improve probabilistic rainfall predictions under future climate scenarios. The Candidate, recently graduated from Duke University (Durham, NC) will join the Host at TU Delft (Delft, The Netherlands) to achieve this research objective, and to continue his postgraduate professional development aimed at creating an independent research program in hydroclimatology.


**Keywords:** Extreme Rainfall,  Hydrology,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Functional thin oxide films obtained by new MOCVD techniques' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

Foreseen ResultsThe aim of the present project is to use the knowledge and the high level of technicity available from the different partners as well in chemistry, CVD processes and material science for the development of emerging materials.The final goal of the present project is to develop MOCVD processes for film elaboration of advanced materials, giving rise to innovative, cost effective integrated layers for several applications. New methods of precursor feeding will be developed to increase evaporation rates and have a better control on stoichiometry and growth. Subsequent reactor development will integrate optimization studies on single cristalline substrates for technological applications.It should be emphasized that this project aims to provide a firm basis for future process developments on oxide layers where, for large scale uses, MOCVD can considerably minimize the cost/quality ratio.The aim of the present project is to develop MOCVD processes giving rise to innovative, cost effective integrated thin films for dielectric, ferroelectric, magnetic and gas sensor, or superconducting applications.Materials to be studied belong to the main family of perovskite like oxide layers (e.g. BaTiO3, SrTiO3, PbTiO3, YBa2Cu307, La-Ba-Mn-O. . .) and to related oxides (CeO2, YSZ..), where solid solutions or subtil changes in composition and control of microstructure allow to tailor the physical property desired.Furthermore, these oxides are excellent candidates as buffer layers for further HTSC film deposition from a microstructural point of view. The development of multipurpose structures will therefore be the final goal of this project integrating systems based on smart materials, microelectronic and superconducting technologies.New MOCVD related methods, based on aerosol
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Formal Truth in Epistemology' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Understanding the notions of truth and knowledge has been at the root of the philosophical enterprise since the very beginning. It turns out that these notions are intimately related and that understanding truth requires understanding knowledge and vice versa. Constitutive questions concerning these notions, such as “Are there truths that cannot be known?” can only be understood, let alone answered, if we have a grasp of both notions. Epistemology, conceived as the study of human knowledge, should therefore simultaneously investigate the notion of truth. Surprisingly, very little research has been conducted from this perspective. Rather research on truth and research on knowledge has been mostly conducted independently. This project will approach the traditional epistemological question of the definition of knowledge from this integrated perspective, and attempt to bridge a gap between current research in epistemology and research on theories of truth. Formal tools and techniques have played an important role in the development of philosophy in the last century. More recently, there has been something like a renaissance of the use of formal methods in philosophy, and in particular in epistemology, with the rise of so-called formal epistemology. The project may be viewed as a contribution to this renaissance since it will make essential use of tools from philosophical and mathematical logic. The ultimate aim of the project is to provide a formal framework for truth and epistemic, or doxastic, notions such as knowledge and belief that is philosophically adequate from an epistemic and a truth theoretic point of view. A unifying framework for the notions of truth and knowledge will prove to be a powerful tool for philosophy, casting new light on several debates in epistemol
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'European Network for Biomedical Ethics: Ethical Problems of In Vitro Fertilization (IVF) with Particular Regard to its Connection with Genetic Diagnosis and Therapy' (IVF).

assistant: **Concept**

When IVF in conjunction with embryo transfer became feasible in the late 70ies there was a heated dispute about principles. This dispute subsided very much when IVF came to be a standardized infertility therapy. But now and then sensational news attracts attention (surrogate motherhood after the mother died, artificial insemination after the menopause). The proposed project, however, shall be concerned neither with the routine nor with the extremes.Rather, experiences with IVF shall be reviewed and analysed with regard to certain ethical questions. In particular, we are working towards an ethical evaluation of the psychosocial consequences and of the medical success rates of this technology. These aspects are the basis for counselling before and after IVF is applied. Further more, fundamental issues in social ethics are at stake which the discussion until now has stated but not investigated thoroughly enough. An example is the problem of a right to a child of one's own and of the technology-assisted satisfaction of such a presumptive claim.This project shall focus on the connecting lines between IVF and genetic diagnosis and therapy. The objective is to discuss preimplantation genetic diagnosis as an alternative to the available procedures in prenatal diagnosis as well as to the possibilities of gene therapy.This new discussion is a research desideratum. The application of IVF might change fundamentally if it were no longer indicated only for infertility treatment but also in order to detect and avoid hereditary handicaps. The ethical key question here is whether eugenic goals can be sufficiently excluded. This discussion requires a comparative review of the ethical debates and of the legal regulations in different countries. The experience available and the future deve