RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Growth hormone: an endocrine factor that integrates thermogenic and circadian signals to regulate brown adipose tissue activity.', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The twin pandemic of obesity and diabetes is one of the greatest health challenges we face today. While fat is at the center of the problem, it may also be part of the solution. It has recently been shown that humans have brown or brown-like fat, whose primary function is to burn, rather than store, energy. This energy-consuming capacity of brown and brown-like fat has the potential to be harnessed to treat obesity and diabetes. The host supervisor has recently discovered that brown adipose tissue (BAT) metabolism is not only controlled by classic thermogenic regulation, but also by the circadian rhythm of the body’s molecular clock. During my PhD training, I observed a doubling in the size of interscapular BAT in mice that lack growth hormone receptor (GHR). I found that BAT has some of the highest levels of Ghr out of all tissues in the body. Despite this, the role of GHR in BAT remains unknown. My preliminary data suggests that GHR is a critical mediator of both thermogenic and circadian regulation. We propose to use genetic gain- and loss-of-function studies accompanied by pharmacologic modulation of GHR to determine its role in BAT. Our in vitro and in vivo work will be complemented by human studies to measure the fuel uptake and thermogenic capacity of BAT. The outcome will be highly relevant to human disease given the enormous potential of BAT activation in the treatment of obesity and diabetes.


**Keywords:** growth hormone, GH, brown adipose tissue, bat, beige adipose, circadian rhythm, thermogenesis, energy expenditure, metabolism, growth hormone receptor, GHR, circadian
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Risk and Migration A Transnational History of Romanian Migration to Western Europe (2002-2013)' to be submitted under Horizon 2020.

assistant: **Abstract**

The liberalization of border controls following the breakdown of the Europe's communist regimes led to important flows of East-West migration. Western Europeans, fearing a literal invasion of Central and Eastern European immigrants, increasingly interpreted this new-found mobility as being fraught with risk. This research project will examine the history of Romanian migration to France and Italy from 2002 until the end of 2013 from the perspective of risk. It will analyse how evaluations of and responses to risk shape the migration process. The first step of this project will be to understand how fear of migration influences political responses and regulatory measures. The second step will investigate how this sense of fear developed and evolved within French, Italian and Romanian societies. It will also analyse how risk perception impacts migrants’ relationships with the host society. Focussing on the migrants’ own perceptions of their mobility, the third step of the project will examine how they respond to risk. An emphasis will be placed on young adults. The inter-disciplinary perspective adopted in this study will provide a more complete history of Romanian migration during the last decade. Drawing on empirical research, this study will focus on the connections that could be established between European citizens. The final objective is to demonstrate the relevance of ‘risk’ in understanding the migration process.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'MEchanisms of Coupling of Ocean Dynamics and Intermediate trophic levels: High Resolution study' (MECODIHR) targeting Horizon 2020.

assistant: **Abstract**

The open ocean is the largest biome on Earth, yet it is the least protected. A major obstacle to its conservation lies in the fine-grained understanding of how marine organisms are affected by the ocean dynamics. In the last decades remote sensing and bio-logging drastically increased our understanding to how phytoplankton (that can be observed from space as ocean color) and large marine animals (that can be followed with sensors directly attached to them) responds to oceanic turbulence down to the mesoscale (few weeks-months, 10-100 km). A major knowledge gap still concerns the so-called ""intermediate trophic levels"" (ITLs, i.e. zooplankton and micronekton,) and how mesoscale currents (such as fronts and eddies) affect them. This is the focus of the MECODIHR project. The project uses an unprecedented combination of remote-sensing, and  modelling on a multi-disciplinary in-situ database collected in the North-West Atlantic to identify patterns in the distribution of ITLs, relate them to physical structures and biogeochemical observations and make hypotheses about why such relationships arise. High-resolution state-of-the-art modelling allows to test the validity of the formulated hypotheses, clarify the mechanisms behind observed co-localisations and expand the extent of findings. High resolution in-situ measurements and modelling allows to approach how submesoscale dynamics (and its inter-seasonal variability) affect the distribution of ITLs. The MECODIHR results, acquired between the two multidisciplinary highly-reknown oceanographic laboratory of the University of Washington (outgoing phase : 2 years) and the Université de Bretagne Occidentale (incoming phase : 1 year), will provide critical information for open ocean conservation. The MECODIHR project will also tr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Making Persons with Disabilities Full Citizens - New Knowledge for an Inclusive and Sustainable European Social Model'.

assistant: **Objectives**

DISCIT aims to produce new knowledge enabling Member States, affiliated European countries and the European Union to achieve full and effective participation of persons with disabilities in society and the economy. In investigating the social and political conditions for making such participation a reality, the project adopts a multifaceted understanding of Active Citizenship. Adopting a multilevel and institutional perspective, DISCIT examines how different types of policies (social benefits, social services and social regulation instruments) can be mutually supportive in enhancing Active Citizenship for persons with disabilities.Using the UN Convention on the Rights of Persons with Disabilities (CRPD) as a framework of reference, DISCIT identifies more effective ways to remove and prevent physical, attitudinal, social and organisational barriers to Active Citizenship and participation on an equal basis with others, in a context of rapid social and economic change and evolving conceptions of disability across European societies. DISCIT synthesises policy lessons from a strategic sample of European states: ‘Liberal’ (Ireland, United Kingdom), ‘Conservative’ (Germany, Italy), ‘Social Democratic’ (Norway, Sweden) and ‘Post-Communist’ (Czech Republic, Serbia) regimes. DISCIT involves consortium members from all these countries in addition to Switzerland and Belgium. DISCIT’s results provide new insight into how the European Union can support Member States and affiliated European countries in working towards the realization of the rights of persons with disabilities as expressed in the Fundamental Rights under the EC Treaty and the CRPD. By clarifying the possibilities for a strengthened synergy between policies at diverse levels of governance, DISCIT contributes to knowled
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Cooperative robotics powered by AI and data for flexible production cells'.

assistant: **Objectives**

The high-mix low-volume (HMLV) market scenario requires constant changes in jobs, materials and machines. This implies the need to build highly flexible and intelligent manufacturing environments, that allow a fast adaption of processes and systems to changing conditions, assuring high product quality with lower production costs and energy consumption. This urges manufacturing industries to re-define their production processes for competitiveness and sustainability. Most of the manufactured components have joints, so welding technologies are identified at European level as key enabling technologies for the development of innovative and sustainable manufacturing processes. Among welding technologies, arc-based accounted for 36% of the total in 2020, highlighting its relevance for major European industries. Traditionally robots have been used in mass production industries performing repetitive tasks at acceptable cost and quality levels, sacrificing flexibility for productivity. The cooperation of multiple robots powered with IA and Data technologies offers new operational capabilities in terms of manoeuvrability and manipulability in several industrial processes. COROB proposes the development of a smart cooperative multi-robotic system for flexible and reconfigurable manufacturing to cover HMLV industrial production needs in the current technological context of Industry 5.0. The system will be human-centered and will integrate advancements in robotics, inspection, monitoring, control and AI developed by consortium partners and 15 external third parties through an Open call. The flexible solution will be validated in 2 semi-industrial pilots for automotive sector (Multi-robot cooperative arc welding) and toolmaking industry (Multi-robot cooperative WAAM (wire arc additiv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Delivering justice on a transnational scale in Europe. The Roman Rota and the enforcement of a legal culture of negotiation (c. 1560-1700).'.

assistant: **Concept**

ROTAROM17 aims to understand the Roman Rota as one of the essential tools of the Catholic Church’s transnational governance in early modern Europe. How did this Rome-based court of appeal, which judged in the pope’s name important civil disputes involving the clergy and members of the social elites, succeed in having its authority respected outside the pontifical state? Why did men and women from Spain, Portugal, or Poland expect to find in Rome a better justice, in spite of the long, cautious and costly Rotal procedure? On which grounds did challenges and criticisms of Rota’s jurisdiction have political significance? Our aim is to study this institution which remains poorly known for this period, but also to see law in action in the settling of disputes, as well as the way in which the court’s jurisprudence, used as a reference by legal experts and disseminated in libraries, contributed to the making of a legal culture founded on negotiation. The project’s second objective is to open a new research field on Europe’s oldest still-active tribunal and facilitate access to its massive and under-used documentation by producing essential research tolls and reference works, thus laying strong foundations for future developments of scholarship. ROTAROM17 brings together an international and multidisciplinary team (social, diplomatic, cultural and intellectual history, legal history) and foregrounds primary research, connecting the Rota’s archival funds with a large set of archival funds and libraries in Europe. By renewing approaches to the Roman Rota, its environment, personal, litigants, and jurisprudence, and by opening up access to hitherto untapped documentation, ROTAROM17 will make a major and original contribution to rethinking the structuring role of the law in Europea
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Community disassembly rules and the erosion of ecosystem functions in fragmented landscapes'.

assistant: **Innovation**

This Project aims to provide a better understanding of the causes and consequences of species responses to habitat loss and fragmentation. To address this goal, this Project will use an extensive dataset of more than 10,000 birds and small mammals captured in 65 forest patches of different sizes and connectivity located in six landscapes of the Atlantic Forest of São Paulo, Brazil (three continuous landscapes with over 90% forest cover and three fragmented landscapes with 10, 30 and 50% forest cover respectively). This dataset will be analysed to determine: (i) which assembly rules are structuring communities, and do these rules change with habitat loss and fragmentation or among taxa; (ii) how community disassembly caused by habitat loss and fragmentation affects functional diversity; (iii) which species are more important for ecosystem functioning; (iv) the existence of extinction and functional diversity thresholds; and finally, (v) to determine the minimum area requirements necessary to sustain a viable and functional tropical forest ecosystem. These questions will be tested with the use of analytical frameworks developed in several areas within biology, drawing together advances in phylogenetics, population biology, community ecology, landscape ecology, and multivariate statistics. Therefore, this Project aims to advance the scientific understanding of the processes that govern community dynamics in fragmented landscapes and the consequences of landscape alteration for maintaining a functional ecosystem, and will generate solid predictions that can be used for building objective and accurate conservation strategies in this imperilled ecosystem.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Geographical domain' (1998-2002), addressing dissemination and exploitation.

assistant: **Impact**

The conference will bring together senior researchers, young researchers and people from standardization in the field of Geoinformation (GI). This mixture motivate and emphasize theoretical research, probably leading to new research projects or co-operations, as well as it will clarify and influence emerging standards. With that the results can be exploited directly by the industry related to GI integration or interoperability.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Implications of chediak-higashi protein - lyst - in endosomal protein sorting'.

assistant: **Objectives**

Research objectives and content Preliminary results show that the Chediak-Higashi syndrome protein (lyst) is implicated in protein sorting in the endosomes. We plan to analyze the role of lyst in endosomal protein sorting by identification of lyst domains implicated in this process and lyst binding proteins also implicated in endosomal protein sorting. Objectives: 1.- Confirmation of the direct implication of lyst in endosomal protein sorting in fibroblasts. First, we will confirm that the CHS mutation of lyst is affecting endosomal protein sorting in fibroblasts. Transient expression of suitable plasmid constructs carrying the wild type lyst cDNA will be performed in defective CHS fibroblasts to analyze recovery of normal phenotype. 2.- Identification of lyst domains implicated in endosomal protein sorting. The functional study of different lyst domains will be performed by transfecting full length or mutated plasmid constructs containing truncated versions of lyst into CHS defective fibroblasts, providing the minimal lyst sequence necessary for correct endosomal protein sorting. 2.3.- Identification of lyst binding proteins in fibroblasts. The identification of lyst binding proteins will provide crucial information regarding its function in the endosomes, it will either implicate known proteins (may be, coat proteins) or identify novel proteins directly or indirectly involved in this process. This objective will be approached by three different strategies: a) Two hybrid system b) Binding to recombinant lyst protein c) Co-immunoprecipitations Training content (objective, benefit and expected impact) The recent finding that the protein defective in CHS is involved in endosomal sorting opens novel possibilities to analyze this particular step of intracellular transport.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Application Centric IP/Optical Network Orchestration' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The Internet has evolved into a three layer structure: at the top layer sit the applications generating traffic that is groomed at the IP and/or OTN layers and finally transported at the optical layer. Specific application needs, such as latency or protection requirements, are seldom guaranteed, because they are usually implicit and even when they are not, the need of the grooming layer to map large numbers of small flows into the small numbers of very large and static lightpaths is an obstacle to effective service fulfillment.ACINO proposes a novel application-centric network concept, which differentiates the service offered to each application all the way down to the optical layer, thereby overcoming the disconnect that the grooming layer causes between service requirements and their fulfillment in the optical layer. This allows catering to the needs of emerging medium-large applications, such as database migration in data centers. To realize this vision, ACINO aims to develop an open source, vendor-agnostic modular orchestrator, which will expose to applications a set of high level primitives for specifying service requirements, and then perform multi-layer (IP and optical) planning and optimization processes to map these requirements into a set of lightpaths. The orchestrator will also be able to perform re-optimization, by means of a novel online in-operation planning module. The ACINO consortium has strong industrial foundations, and plans to demonstrate the advantages of its approach in a testbed with commercial equipment in a carrier environment.ACINO’s approach directly addresses the lack of dynamic control of optical networks, by automating planning and configuration tasks, and tackles the limitations in inter data center connectivity by allowing applications
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Technology And Knowledge for European Open Fan Flight' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Reducing the environmental impact of Short-Medium Range (SMR) aircraft is a core priority of the Clean Aviation SRIA which aims to deliver enabling technologies ready for the next generation of SMR aircraft. Propulsion plays a pivotal role in this effort, with the Open Fan engine architecture emerging as the most promising solution to achieve environmental goals while supporting a timely Entry into Service by 2035.Building on the foundations laid by the Clean Aviation OFELIA and COMPANION projects, and leveraging synergies with national funding programmes, the TAKE OFF project gathers a broad European consortium to advance the RISE Open Fan technology demonstration announced in June 2021. The project will culminate in a full-scale, in-flight demonstration of an Open Fan engine, enabling a path to 30% reduction in fuel consumption at the aircraft level and validating TRL6 for the engine architecture.TAKE OFF is structured to cover the entire demonstration chain—from final engine design, assembly, and instrumentation, through aircraft platform integration and flight clearance, to post-flight data analysis and model calibration. TAKE OFF also paves the way for future certification of Open Fan products. Early and continuous engagement with airworthiness authorities, development of draft regulatory material, and application of the Certification Readiness Level (CRL) framework will ensure alignment with evolving regulatory needs.Fully aligned with the Clean Aviation roadmap under the SMR pillar, TAKE OFF provides essential propulsion-level evidence to guide system-level design and de-risk industrial investment. By delivering flight-proven data, refined digital tools, and matured technologies, TAKE OFF will reinforce Europe's leadership in sustainable aviation and accelerate t