RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Law Enforcement Intelligence Learning Application' to be submitted under Seventh Framework.

assistant: **Abstract**

21st Century security challenges raise questions about the effectiveness of the traditional intelligence learning paradigm suggesting the need of a complex, agile and rapidly changing intelligence analysis approach.In this context, via a holistic learning methodology and a “serious games” solution, the LEILA project will enable to empower intelligence analysts by improving their cognitive capabilities, reasoning skills and creative approach, at individual and group level.The radical innovation of this holistic approach is brought by the combination of several fields which are normally explored and applied separately such as: psycho-sociological and cognitive factors in decision making (e.g. decision biases, critical thinking, multiple reasoning strategies, creativity), decision making strategies under uncertainty (e.g. Bayesian approaches, game theory), and group interaction dynamics in intelligence analysis.A variety of learning experiences (e.g. games of deterrence, intelligence analysis under stress, emergence in highly of collaborative situations) will be elaborated and computerized in different serious games, that will offer the possibility to actively acquire the new IA skills from the different angles.The impact on users’ community will be ensured by partners providing knowledge and learning in the specific domain (NDU, KEMEA, ZANASI), by the early and continuous involvement of end users and stakeholders (partners and their networks), by the iterative design process - alternating pilots and implementation of the learning framework and the serious games - and the intensive dissemination activities.The involvement in the consortium of experienced SMEs in the domains of Serious Games, innovative interfaces, technology enhanced learning, together with important key p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Analysis of the structure and function of a cellulose binding domain' to be submitted under Fourth Framework.

assistant: **Abstract**

Research objectives and content Recent studies have demonstrated that cellulose binding domains (CBDs) play an important role in the activity of plant cell wall hydrolase against insoluble substrates. Pseudomonas enzymes consist of two distinct CBDs; a type II CBD domain and a second smaller domain. Although recent studies have shown that removal of both CBDs decreases the activity of Pseudomonas xylanase A (XYLA) against cellulose/hemicellulose complexes, it is unclear why Pseudomonas enzymes contain two distinct CBDs. The objective of this proposal is to determine the properties of the 40 residue CBD of XYLA and its role in the action of XYLA against the plant cell wall. Specifically, site-directed mutagenesis will be used to change the conserved aromatic residues to alanine to establish whether they play a pivotal role in binding cellulose, or are integral to the correct folding of the CBD. To establish the importance of the CBD in the activity of XYLA, xynA will be engineered such that it encodes two derivatives of XYLA in which either the large type II CBD (XYLA') or the small CBD (XYLA) has been removed. Analysis of the capacity of XYLA, XYLA' and XYLA" to hydrolyse cellulose/xylan complexes will establish why Pseudomonas glycosyl hydrolase, in general, have two distinct CBDs. Training content (objective, benefit and expected impact) This project will provide me with an excellent training in the use of recombinant DNA technology (site-directed mutagenesis, PCR, DNA sequencinge etc) to study the structure and function of proteins. I already have experience in the use of both biochemical and chemical techniques to study industrially important enzymes. At the completion of my training I will be able to use recombinant DNA technology to produce large quantities of the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Depicting Species: The Role of the Image in Modern Biology 1750-1950' to be submitted under Horizon 2020.

assistant: **Abstract**

This project investigates the visual cultures of zoological systematics informed by practices, techniques, genres, ideas, materiality, norms, producers, and audiences. Approaching systematics through its rich pictorial legacy, I explore how thinking through images in using them as research tools produces distinct species concepts and how images used as training or teaching devices informed species concepts. The timeframe of this investigation spans three centuries and explores two hundred years of biological research between Linnaeus’ first attempt to standardize zoological nomenclature in 1758 and the “Modern Synthesis” of evolution and heredity in the 1930s and 1940s. On the basis of the empirical examination of archival collections and printed materials, I examine the functions, production, and usage of zoological illustrations within biological research (objective 1) and follow their circulation among lay audiences (objective 2). I will approach the material from an interdisciplinary perspective. This involves first an iconographic method as a foundation for a comparative evaluation. I draw here on both scientific and artistic practices. Second, I embed the production of zoological illustrations within the framework of cooperative knowledge production between different groups of actors stemming from different intellectual, educational, social, and national backgrounds. This will be the first study of the transformation of pictorial scientific practices in systematics between 1750 and 1950 and how they redefined the boundary between expert and lay audiences. The book resulting from this research will draw a vivid panorama of scientific knowledge production carried out by zoologist, artists, technicians, and amateur scientist.


**Keywords:** history of biology, natur
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Integrated Communication System for Intelligent Train Applications'.

assistant: **Innovation**

The TRAINCOM project intends to fully specify and develop a communication system for telematics applications in the railway field, integrating the on-board network (e.g. TCN), GSM radio links and Internet technologies. Based on this system, which offers ubiquitous remote access to on-board equipment, the project will develop two important applications related to dynamic passenger information and locomotive interoperability, setting up validation sites in different Countries. The project will focus on and contribute to main issues like standardisation and interoperability. A conformance test specification for TCN will be prepared and a suitable automatic testbed developed, so as to favour interoperability of devices and subsystems. Interoperability of applications will be considered in all specifications, which will be proposed for standardisation. An architecture and some basic elements of a maintenance support system, for remote, real-time monitoring of equipment on board trains, will be developed as well.Objectives:· open and integrate the railway equipment market· favour the interoperability at train, vehicle and equipment level· reduce the life cycle cost of railway vehicles· improve services for citizens and allow new value added services· make railways more competitive (increase of market share)· improve comfort of passengers and enhance attractiveness of the public transport· integrate existing and new technologies (notably Information and Communication Technologies) in railway applications· enable train fleet maintenance management based on remote monitoring and diagnostics· pave the way for the establishment of a complete normative platform for railway equipment· contribute to the next generation of railway vehiclesWork description:The TrainCom project will :·
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Nanolasers for in-vivo deep in tissue neuron activation and action potential sensing' to be submitted under Horizon 2020.

assistant: **Abstract**

SummaryNanolasers offer the ultimate photonic gadget with unique properties as biosensors and actuators. Lasers at the nanoscale can concentrate high optical powers in small volumes and use a fraction of the power required to drive a conventional laser. Recently, nanolasers and nanoresonators have seen use for biosensing, with the focus so far on in-vitro biochemistry. Translating this approach to in-vivo is complex but promises to link relevant in-vivo physiological information with chemical pathways. This project aims to integrate photonic architectures for in-vivo deep-tissue exploration and to translate this technology to areas where probing the local environment with light has an immediate impact, such as the Brain. My proposed research thus bridges different scientific disciplines exploring the physics of biological sensing.I foresee 3 major efforts to succeed in this research:1 – Design of micro- and nanocavities operating in the IR.2 – In vitro characterization through highly scattering media. 3 – In vivo investigations for deep-tissue sensing.


**Keywords:** Intracellular laser, upconversion, nanolaser, deep-tissue, sensing, neural probe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The PREfrontal CHRONometer for Organizing Working Memory' to be submitted under Horizon Europe.

assistant: **Abstract**

Working memory (WM) is a crucial part of human cognition, yet how the brain maintains and organizes different pieces of information is unresolved. I propose that spike-field coupling (SFC), which is the exact moment in time when a neuron spikes in relation to the surrounding neural oscillation (field), is what organizes WM content. Accordingly, different WM items or features are maintained through SFC at different phases of prefrontal brain oscillations. Metaphorically, the prefrontal oscillation represents a chest, where each phase is a drawer. Neural spiking opens the drawer, allowing specific data to be maintained separately from other data. While this idea is supported by animal research, due to the invasive nature of used methods, evidence in humans is missing. Novel technology, which combines non-invasive neuromodulation (TMS) and physiological recordings (EEG) in a closed-loop system, now enables phase-specific SFC to be non-invasively induced in humans.By leveraging and further developing closed-loop TMS-EEG, PRECHRON will test the idea that the interaction between spiking and oscillation in the prefrontal cortex is the mechanism for separating maintained WM information. Based on previous studies, the focus will be on theta (4-7 Hz) oscillations. PRECHRON will test four independent, non-mutually-exclusive hypotheses: 1. SFC at a resting state (no task) predicts overall WM performance; 2. Phase-specific SFC during a WM task organizes WM of different domains (e.g., verbal and spatial); 3. Phase-specific SFC during a sequential WM task organizes the temporal order of WM items; 4. Phase-specific SFC during a visuospatial WM task organizes the location of WM items. Thus, PRECHRON will explore, for the first time, exactly how the prefrontal cortex maintains various ty
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Tilt Rotor INlet Innovative Design And Testing' (TRINIDAT).

assistant: **Innovation**

The TRINIDAT project adresses the aerodynamic characterization of an already available intake geometry (as supplied by ITD) and optimization of the intake performance by using CFD based optimization tools leading to redesigned high performance intake shapes to be implemented on the Next Generation Civil Tilt Rotor (NGCTR) configuration. A purpose of the optimization is to improve the flow steadiness and uniformity at the Air Intake Plane of the engines such as to comply with the requirements put forward by the engine manufacturer. The initial characterization and optimization will rely on dedicated CFD studies, the final validation will be made with full size model tests in DNW-LLF 6x6 wind tunnel, allowing reliable testing at full scale Mach and Reynolds conditions. For efficient testing of basic and optimized left hand and right hand intake geometries in airplane, helicopter and intermediate Extreme Short Take-Off and Landing mode, a modular wind tunnel model equipped with a remotely controlled tilting forward nacelle part will be designed and manufactured. A remotely controlled highly instrumented rotatable rake will be installed in the model to enable detailed and efficient measurement of the flow at the engine air intake plane. Apart from the aerodynamic optimization of the intakes, the project will also identify icing and snow conditions to be considered for certification and will subsequently analyse the ice and snow effects on the nacelle inlets and ducts to provide early input for anti icing measures that might be needed for NGCTR.The partners of the consortium, gathering renowned Research Centres (NLR, DNW), 2 Industrials (Deharde, ALTRAN), 1 SME (ADSE) and 1 University (UT), will use their complementary expertise and facilities to provide an optimized inlet g
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'CAUSATION: Assessing causal relationships in Macroevolution' to be submitted under Horizon Europe.

assistant: **Abstract**

Throughout earth’s history, a myriad of factors has driven biodiversity patterns. During the lifespan of lineages, biotic and abiotic variables might act differently in shaping the diversification dynamics of organisms. Therefore identifying and quantifying their relative importance is crucial for a better understanding of past and current biodiversity patterns. This is particularly relevant for complex systems involving multiple functional groups spread through different trophic levels, e.g. the system composed of browsing and grazing animals and the plants they consume. The dynamics of the whole system can be affected not only by the biological components but also by environmental factors. Recently, new methods have been proposed to directly address causal associations between time series, based on dynamic systems theory, which represents an advancement in relation to traditional correlation-based approaches. This proposal will assess the causal associations between the diversity of each component of the plant-herbivore system to have a better understanding of the mechanisms involved in the regulation of biodiversity in macroevolutionary timescales. Using the “Empirical Dynamic Modelling” (EDM) approach, which is a non-parametric approach specifically designed to address causality in time series, I will test the performance of this approach when using simulated and empirical macroevolutionary time series, applying it to the diversity time series of the components of the plant-herbivore system. This project will produce a critical examination of the performance of the EDM approach in this context, as well as produce direct information on the causal associations between the diversity of different groups and the influence of environmental variables on the dynamics of the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Control of the Structure of Light at the Nanoscale' in the context of a Seventh Framework call.

assistant: **Objectives**

In the last decade, the fields of nanoplasmonics and photonic crystals have opened up the nanoscale for optical control. Both the flow and emission of light can be controlled at these small length scales, giving rise to new science and applications. Interestingly, freely propagating light beams can already contain nanoscale features, i.e. optical singularities. Little is known about this nanoscale structure of light.I propose to (1) reveal the structure of light at the nanoscale and its interaction with geometrical structures or other light structures; and (2) achieve full spatio-temporal control of the nanoscale structure of light. Crucial to achieving these goals are technological innovations, which will be crosscutting objectives. These include the first nonlinear vectorial scanning near-field microscope and novel near-field probes allowing access to new combinations of vector fields.This next step in the field of nano-optics is possible due to recent breakthroughs in the control and visualization of light at the nanoscale obtained in my group. I will combine newly acquired access to the vectorial nature of light with its active control to investigate how (deep-) subwavelength structures of light of different frequencies affect each other when coupled through a nonlinear interaction in a nanostructured material. In parallel I will focus on optical singularities. Because of their extreme size, small changes in their position will lead to huge effects in the local light fields, opening up potential for all-optical and therefore ultrafast control.The research will lead to innovations in the visualization and control of light at the nanoscale, access to the magnetic component of light, nanoscale nonlinear optics and coherent control of light fields. The knowledge gain wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Positron Annihilation Lifetime Spectroscopy for Revealing and Quantifying Inflammation and Endothelial Diseases' (ALFRED) targeting Horizon Europe.

assistant: **Abstract**

Inflammatory processes have been identified as major contributors to various mental and physical diseases, significantly impacting global morbidity and mortality. Many of these conditions involve changes in the microvascular permeability that are challenging to early detect due to limitations in current diagnostic tools, which are either invasive or lack sufficient resolution. There is an urgent need for improved methods to detect and measure microvascular permeability. To advance the field, I will use Positron Annihilation Spectroscopy (PAS) to quantify alterations in the capillary endothelial wall integrity directly, known to be correlated to the endothelial permeability. PAS is a non-destructive, label-free technique that measures molecular dynamics at the nanoscale. By irradiating materials with positrons and analyzing their resulting annihilation events, PAS can provide real-time observations of nanostructural changes in biological tissue.To achieve my goal, I will engineer a robust capillary endothelial wall model and I will characterize endothelial wall permeability changes under various pharmacological conditions, by using electrophysiological techniques. To perform intravital PAS on this in vitro model, I will develop a novel perfusion bioreactor, able to withstand high vacuum conditions and to interface biological matter with positron sources. I will then correlate PAS outputs with the ones of conventional techniques. To optimize drug concentration required to measure PAS variations, I will realize a numerical predictive model. Finally, I will validate my approach on the highly vascularized respiratory membrane of embryonated avian eggs. This project combines bioengineering, particle physics, and medical imaging to address a critical gap in current diagnostic