RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'The Geometry of Higher Symmetries'.

assistant: **Innovation**

Symmetry structures are key to organizing the complexity of physical systems. In systems described by quantum field theories (QFTs) symmetries group observables, classify phases, determine selection rules and give insight into strongly coupled dynamics. They are irreplaceable in the study of phenomena such as confinement or duality. Recently, the notion of ‘symmetry’ in quantum field theories was understood to admit a substantial generalization to higher categorical structures such as n-groups and non-invertible symmetries. These realize further non-perturbative data yielding new handles in the study of QFTs. The goal of this project is to analyze such symmetry structures in geometrically engineered QFTs. We initially focus on theories in 4d parametrized by spectral curves and/or special holonomy spaces and aim to geometrize the symmetry representations and fusion structures related to their higher symmetries, building on both past work of the researcher and supervisor. This approach, unlike recent field theoretic developments, does not rely on a Lagrangian description of the QFT and therefore offers insight into confining properties and phase structures of strongly coupled systems. The foremost research objective of this proposal lies in charting these structures for increasingly less supersymmetric theories, including theories with no supersymmetry. All current evidence suggests that such symmetry structures only depend on topological data of the spectral curves and special holonomy space which we aim to trace through supersymmetry breaking deformations. Further research objectives include the study of analogous symmetry structures for superconformal theories in 5d and 6d. Such theories are intrinsically strongly coupled and the geometric methods developed in 4d, guid
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Electronic structure of nanosystems: Density Functional Theory approach'.

assistant: **Objectives**

One of the core concepts in nanoscience and nanotechnology is the bottom-up approach, taking electrons, atoms, or molecules as the building blocks from which to create man-made nanosystems with the specific and desired electronic, biological, material, mechanical, or environmental properties. This approach however, poses a new and fundamental scientific challenge: the mastering of the way in which electrons, atoms, or molecules interact which each other, governed by the non-intuitive laws of quantum mechanics. This challenge drives in turn the search for better and accurate calculation methods aimed to the prediction, with the largest reliability as possible, of the properties of a particular array of electrons or atoms (nano-design).   The present research training project points towards the fulfilment of this goal: the development and application of Density Functional Theory (DFT) methods specially designed for the treatment of interacting strongly inhomogeneous electron gases as those formed in semiconductor quantum wells and dots. The research plan is divided in three parts:  a) the static case without magnetic field,  b) the static case with magnetic field, and  c) the time-dependent case.  In all cases, the so-called Optimized Effective Potential (orbital-based functionals) method of DFT will be the general framework of the calculations.   While the utility of this method at the exchange level has been already demonstrated, its value at the correlation level still is an open question. The application of orbital-based functionals to the calculation of the electronic properties of quantum-confined systems is still in their infancy. The present project aims to contribute to close this gap, appealing to an almost ideal match between the expertise of Prof. Gross and th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'NANO-SCALE ACCURACY ANALYSIS OF DIAMOND FILMS FOR ADVANCED TECHNOLOGIES USING ULTRA LOW ENERGY SECONDARY ION MASS SPECTROMETRY AND OTHER TECHNIQUES.'.

assistant: **Innovation**

Due to its remarkable properties, diamond has a huge potential as the basis of several new technologies. Its effective development will depend on the ability to tailor its chemistry and structure on tenant-scale. This project's objective is to form a basis for the measurement of doping and impurity profiles in diamond, accurate on the Nan scale, via ultra low energy SIMS (dualisms).The project will start with a basic study of ion beam-surface interactions for diamond. In parallel, reference materials will be designed and produced. The next step is to quantify ion beam broadening effects, very important if sharp patterns are to be measured. Next, the limits of shallow profiling due to the transient behaviour will be determined. Finally, the developed methodology will be used in applications measurements. Fulfilment of the objectives will help the development of a wide range of technologies, especially electronic devices where control of the doping profile is in its infancy. Regarding the training objectives, the applicant will receive full training in the use of state of the art use-SMS instrumentation. She will gain a deep knowledge in a key material for the development of new technology. Moreover, the researcher will become familiar with a wide range of analytical techniques in support of the central SIMS analysis.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Integration of EO-data in enforcing national legislation for environmental forest management'.

assistant: **Innovation**

The main aim of the ENFORMA pilot project is to demonstrate the preoperational use of Earth observation (EO) by forest authorities. These organizations are responsible for enforcing national forestry legislation, the aim of which is sustainable forestry. The Co-ordinator for the ENFORMA project is the Swedish Space Corporation. Other partner organizations providing EO expertise in forestry are VTT Automation, Finland, and Geospace, Austria. Cooperation with the users is an essential part of the project. The three user organizations are also partners in the project: National Board of Forestry, Sweden; Forest Development Centre Tapio, Finland; and Landesforstdirektion Salzburg, Austria. The goal of the project is to significantly improve the effectiveness and cost-effectiveness of the forest authorities efforts to follow-up forestry activities. A major focus is to see whether forest owners keep to the environmental forestry methods required by law. The EO data will allow a first assessment to be made before field inspections. A goal is to optimise these inspections through improved planning using the EO information. The project will be based upon existing mature techniques for forest change detection from EO. These will be optimised to the specific information and operational needs of the users. A major innovation will be the integration of Earth observation data and processing functions into a single package designed for use locally within these organizations. The project involves demonstrations in Sweden, Finland and Austria. These three new EU Member States all have significant forestry sectors. Demonstrations of the pre-operational use of a prototype EO forest management product will take place within several forestry districts in each country. The measurable objectiv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Development of Experimental Techniques and Predictive Tools to Characterise Thermo-Mechanical Fatigue Behaviour and Damage Mechanisms'.

assistant: **Innovation**

DevTMF takes the collective technical expertise and experience of working on thermo-mechanical fatigue (TMF) problems related to large aero-engines from three major centres of TMF research, namely Linköping, Swansea and Nottingham Universities in order to perform the activities of this topic. Together, the team will deliver significant technical innovations in following major topics to ensure world-leading competencies in aero engine and aircraft manufacturing sector for Europe:1. Improvement and development of advanced standard and non-standard cutting-edge TMF experimental methods and harmonisation of the test methods to enable standardisation across the field by performing comprehensive studies into the phenomena for a range of representative parts,2. Advanced metallurgical assessment of structural disc alloy(s) taking into account the effect of multiple critical variables (e.g. R-ratio, phase, environment, dwell) to determine active damage mechanisms that control the life under TMF operating conditions, and3. Physically based coupled models, with experimental validation, capable of predicting TMF initiation and propagation lives of components subjected to complex engine cycles and suitable for implementation in the computer programmes used to predict component lives.The project will take the above-described technologies to TRL5. Two business opportunities are addressed by this work: (i) at the end of the project the materials understanding and lifing models will be used to optimise/uprate the performance of existing individual aero engine components and (ii) over a longer timescale influence the development of new disc alloys and ultra efficient future designs (Advance, Ultrafan). The developed TMF technologies will enable industrial aero gas turbines used for aero
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Collective personalities: from individuals to groups, and back' in the context of a Horizon 2020 call.

assistant: **Objectives**

Many organisms, including humans, group together and perform collective actions such as birds forming coordinated flocks to evade predators, forage or roost. Some, as social insects, have evolved complex societies in which the unit of selection is not the individual, as in most vertebrates, but the colony. Yet, in both there is evidence of consistent behavioural variability among both individuals and groups. The study of collective behaviour - coordinated actions resulting in emergent properties at the group level - and the study of animal personality - between individual differences that are consistent over time and contexts - have progressed tremendously in the last two decades and are converging in their search for the link between individuality and collectivity, a fundamental and timely issue in biology. The GROUPIND project aims to investigate the relationship between individual personality and group personality by using ants and starlings as study organisms, both of which showing distinct collective behaviour and marked individual behavioural variability. The project will use a comparative approach to address the following objectives: (1) To characterize, also upon experimental manipulation, the composition of personalities in the group and understand how this relates to personality at the group level. Are group personalities an average of individual personalities within the group? Do they result from different distributions of individual personalities? Are there keystone individuals that exert a disproportionate influence on the group personality? (2) To understand how diversity of individual personalities contributes to decision making and to the ecological success at the group level, and how this would feed back at the individual level. By bridging two major fi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Addressing the role of self-organization in tumor heterogeneity and plasticity'.

assistant: **Concept**

Colorectal cancer (CRC) remains a major health challenge, with a survival rate of 15% in stage IV cases due to therapy resistance and tumor relapse. A key barrier to effective treatment is the high degree of intratumor heterogeneity and plasticity. These features enable the coexistance of diverse cancer cell populations within a tumor, each of them specialized in key functions such as proliferation, invasion or resistance to treatment. Additionally, phenotypic plasticity grant these cancer cells flexibility to dynamically tune their phenotype, to the extent that a single surviving cell can regenerate a full heterogeneous tumor. Despite their crucial role in CRC pathology, the biological mechanisms driving tumor heterogeneity and plasticity remain poorly understood.Current research suggests that tumor plasticity is driven by microenvironmental cues, where external signals induce specific cell states within localized tumor niches. However, my preliminary data reveal that cancer cells possess an intrinsic ability to self-organize and establish heterogeneity even in the absence of external signals. SelfOrg will tackle the unexplored contribution of self-organization to tumor heterogeneity and plasticity. To do so, I will combine quantitative measurements in bioengineered human organoids with physiologically relevant mouse tumor models to dissect the intrinsic mechanochemical signals regulating tumor heterogeneity. A systematic, image-based analysis of a patient-derived organoid (PDO) biobank will further assess the clinical implications of self-organization for patient prognosis.By leveraging my expertise in organoid mechanobiology and the host lab's proficiency in PDOs and translational cancer research, SelfOrg is uniquely positioned to address the problem of tumor heterog
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'PRodrug technology for Immunotherapy-priming via patient-friendly at-home MEtronomic dosing' (PRIME), addressing dissemination and exploitation.

assistant: **Impact**

Immunotherapy holds great promise for curative cancer treatment. While immune checkpoint inhibitors can induce complete and long-term cures, the percentage of patients responding to immunotherapy remains to be low. Combining immunotherapy with chemotherapeutic drugs that induce immunogenic cell death (ICD) is among the most promising strategies to potentiate antitumor immune responses. Chemotherapeutics are clinically typically administered via intravenous infusion, once every couple of weeks, at high doses. Metronomic dosing is based on the application of chemotherapy drugs at high frequency and low doses, and it is gaining increasing interest to potentiate chemo-immunotherapy responses. However, high-frequency low-dose chemotherapy administration in the clinic via intravenous infusion is pragmatically undoable and economically not feasible. At-home administration via oral ingestion or subcutaneous self-injection is impossible, because of the side effect spectrum of chemotherapeutic drugs. In the PRIME project, we aim to establish PRodrug technology for Immunotherapy-priming via patient-friendly at-home MEtronomic dosing. Prodrugs have assisted in improving drug performance for over a century now, and they are widely employed in pharmaceutical industry and clinical practice, with approximately 10% of new drug approvals technically being prodrugs. We will set out to establish a synthetic and formulation strategy to produce a novel immunogenic prodrug platform, and upon subcutaneous metronomic dosing, we will evaluate the preclinical performance of our prodrugs as monotherapy and in combination with immunotherapy in breast and prostate cancer mouse models. We anticipate that exploiting the technological and socio-economic potential of PRIME will unlock new avenues toward
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Quantum Microwave Communcation and Sensing' (QMiCS) targeting Horizon 2020.

assistant: **Abstract**

The mission of QMiCS is to combine European expertise and lead the efforts in developing novel components, experimental techniques, and theory models building on the quantum properties of continuous-variable propagating microwaves. QMiCS’ long-term visions are (i) distributed quantum computing & communication via microwave quantum local area networks (QLANs) and (ii) sensing applications based on the illumination of an object with quantum microwaves (quantum radar). With respect to key quantum computing platforms (superconducting circuits, NV centers, quantum dots), microwaves intrinsically allow for zero frequency conversion loss since they are the natural frequency scale. They can be distributed via superconducting cables with surprisingly little losses, eventually allowing for quantum communication and cryptography applications. Radar works at gigahertz frequencies because of the atmospheric transparency windows anyways. Scientifically, QMiCS targets a QLAN demonstration via quantum teleportation, a quantum advantage in microwave illumination, and a roadmap to real-life applications for the second/third phase of the QT Flagship. Beneath these three grand goals lies a strong component of disruptive enabling technology provided by two full and one external industry partner: the development of a microwave QLAN cable connecting the millikevin stages of two dilution refrigerators, improved cryogenic semiconductor amplifiers, and packaged pre-quantum ultrasensitive microwave detectors. The resulting ""enabling"" commercial products are beneficial for quantum technologies at microwave frequencies in general. Finally, QMiCS fosters awareness in industry about the revolutionary business potential of quantum microwave technologies, especially via the advisory third parties “Ai
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Measuring Hubble's Constant to 1% with Pulsating Stars'.

assistant: **Concept**

What's up with Hubble's constant (H0)? Recent H0 measurements have shown that the Universe is expanding faster than cosmology predicts, indicating a possible cosmological crisis. To wit, H0 measured to 1.9% precision in today's Universe using a cosmic distance ladder composed of classical Cepheids and type-Ia supernovae differs by 8.9% (4.2 sigma) from H0 predicted by cosmology based on observations of the Cosmic Microwave Background emitted 13.8 billion years ago. However, it remains unclear whether new physics must be invoked to reconcile cosmology with today's H0, or whether today's H0 is subject to as yet unknown or underestimated systematic errors. An unbiased 1% measurement of H0 is required to understand whether physics is on the brink of a major breakthrough.So, how solid is our distance ladder? To answer this, my research seeks to a) mitigate biases that can shift the center value of reported H0 measurements, b) quantify relevant systematic uncertainties, and c) reinforce the foundation of the distance ladder through a solid astrophysical understanding of pulsating stars, in particular, classical Cepheids. These steps must be taken now to achieve an unbiased 1% H0 measurement and to ensure the legacy of today's distance ladder for future space-borne facilities and ground-based extremely large telescopes. Imminent data releases of the ESA mission Gaia and precise time series spectroscopy will provide unprecedented opportunity to calibrate the distance ladder and unravel the structure and evolution of Cepheids through their variability.The H1PStars project will leverage my expertise in the astrophysics of classical Cepheids and the calibration of the distance ladder to support precision cosmology via accurate stellar physics, and vice versa. Thanks to this fresh
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Renewable Energy: Best Practice Projects Yearbook'00' (1998-2002).

assistant: **Concept**

The main objective of the Renewable Energy: Best Practice Projects Yearbook'00, will be to highlight the benefits of renewable energy technologies and encourage co-operation between industries by proving the technological and economical viability of the technologies described. Therefore this project will compile and promote information about the evolution of the renewable energy sector and of the best renewable energy projects undertaken within the European Union and Norway during the period 1997-2000. This project aims to provide an overview of some European renewable energy projects that can be considered to be best practice because of the results obtained and the introduction of innovative technologies or new commercial applications. This project will provide energy stakeholders with a better knowledge of the current market situation.