RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Science for Water Policy - Implications of the Habitats Directive' (1998-2002) under Fifth Framework.

assistant: **Objectives**

The conference, organised by the Marie Curie Fellowship Association, in cooperation with the University of East Anglia and ETNET 21 Environment-Water, will focus on how science can contribute to policy, along the lines of the water framework directive, i.e. all aspects of water management from groundwater to surface water, from freshwater ecosystems to estuaries and coastal waters. It will bring together young scientists from all disciplines to interact with senior scientists and present their work on water research, with the objective of: (i) training them to expose their approaches to scientists from other disciplines and (ii) encouraging them to think about the policy consequences of their research.The conference will be organised over three days. In the first two days, the morning will be dedicated to keynote speeches from key actors in the European water sector (European Commission, NGOs, Industry, National Governments). In the afternoon, a selected number of young scientists will have the opportunity to present their research in parallel sessions dedicated to the main areas of the Water Framework Directive (surface and groundwater ecology, surface and groundwater chemistry, economics of water use). Papers will be selected by the conference organising committee, after a call for abstracts open to young researchers from all backgrounds. Criteria for selection will include: degree of innovation, policy relevance, geographical representation and gender balance. Sessions will be chaired by senior scientists, who will first give an overview of the state of the art in their field of research, and preliminary thoughts on the implications of the Water Framework Directive in their research field. For young scientists who could not present their research in parallel sessions
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Satellite-based communications systems within IPv6 networks' (SATSIX), addressing dissemination and exploitation.

assistant: **Impact**

The SatSix project will implement innovative concepts and cost-effective solutions for broadband satellite systems and services. The project will promote the introduction of the IPv6 protocol into Satellite-based communication systems. It will also contribute to the implementation of the eEurope Action Plan by defining new cost-effective satellite system solutions and encouraging the use of satellites as an enabler for universal access to e-services.A prime focus for these systems will be service platforms built upon the sound basis established by the European DVB (-S2 and -RCS) standards for satellite systems. It is also important that, through SatSix, the industry addresses the next generation Internet and increased Internet IP address space ( as offered by IPv6) and enhances its competitive position in Satellite Broadband Multimedia Systems by exploiting the common components defined by the European DVB-S2 and DVB-RCS broadband standards.To achieve these objectives, the SatSix project has chosen a 4-step approach:- Identification and analysis of the impacts of IPv6 on Satellite-based network: Integration of heterogeneous networks (Sat +WiFi,Sat+WiMax,..) .Validate the concept by simulation followed by emulation using a testbed- Support live experimentation with end-to-end applications (eEurope).To achieve these goals, the SatSix consortium brings together leading actors in the field: satellite and telecommunication industry, operators, SME's, research institutes and universities. This project is key to reduce the «digital divide», between urban and rural areas, and also between regions by ensuring service continuity over heterogeneous networks.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Quantum-mechanical modeling of the dissociation of hydrogen bonds' (2021-2027).

assistant: **Innovation**

Hydrogen bonds are everywhere in nature, and they are important in many fields of science. Well-known examples come from biology (helix structure, protein folding, enzyme docking), chemistry (solvation, structure and properties of water), and atmospheric science (nucleation and growth of aerosols). Today, the spectroscopic features of hydrogen bonds are relatively well understood, but much less is known about the associated ultrafast dynamics. The theoretical models that are used to understand and design present ultrafast experiments are often based on classical or semi-classical approximations to describe the movement of the nuclei. With the recent advances in both theory and ultrafast imaging techniques, we believe that the time is ripe for a full quantum mechanical picture of hydrogen-bond dissociation. A quantum mechanical picture of hydrogen bond dissociation will contribute to the basic understanding of chemical, biological, and atmospheric processes. In this project, I will perform a comprehensive quantum mechanical study of the hydrogen-bond dissociation dynamics of a small hydrogen-bound complex, pyrrole-H2O. The calculations will be performed in a reduced-dimensional framework, for which the central hypothesis is that certain vibrations dictate the dissociation process while other vibrations serve as spectators. The dissociation process will be initiated through an infrared excitation that provides just enough energy to dissociate the complex, but not enough energy to initiate other unwanted processes. We will establish how the reaction mechanisms for hydrogen-bond dissociation manifest themselves in the ongoing ultrafast dynamics experiments performed in the Controlled Molecule Imaging (CMI) group. The calculations will be tailored to design and simulate real
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'MIND CONTROLLED ORTHOSIS AND VIRTUAL REALITY TRAINING ENVIRONMENT FOR WALK EMPOWERING' (MINDWALKER).

assistant: **Concept**

A lack of mobility often leads to limited participation in social life. The purpose of this STREP is to conceive a system empowering lower limbs disabled people with walking abilities that let them perform their usual daily activities in the most autonomous and natural manner. New smart dry EEG bio-sensors will be applied to enable lightweight wearable EEG caps for everyday use. Novel approaches to non-invasive BCI will be experimented in order to control a purpose-designed lower limbs orthosis enabling different types of gaits. Complementary research on EMG processing will strengthen the approach. A Virtual Reality (VR) training environment will assist the patients in generating the correct brain control signals and in properly using the orthosis. The main BCI approach relies on Dynamic Recurrent Neural Network (DRNN) technology applied in a two stages process. After learning, the system will be able to match EMG signals to legs movements (Stage 2), and EEG to such EMG signals (Stage 1). The Stage 2 has already been successfully demonstrated by a project partner. The orthosis will be designed to support the weight of an adult, to address the dynamic stability of a body-exoskeleton combined system, and to enable different walking modalities. The VR training environment will comprise both a set of components for the progressive patient training under a safe and controlled medical environment, and a lightweight portable set using immersive VR solutions for self-training at home. The developed technologies will be assessed and validated with the support of a formal clinical validation procedure. This will allow to measure the strengths and weaknesses of the chosen approaches and to identify improvements required to build a future commercial system. In addition the resultin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'A NOVEL NON-INVASIVE SOLUTION FOR CONTINUOUS BLOOD PRESSURE MONITORING' under Horizon 2020.

assistant: **Concept**

Blood pressure follow-up is essential in managing hemodynamically unstable patients at Intensive Care Units (ICU). Traditionally, mercury sphygmomanometers have been used for this purpose, and are regarded as the gold standard for Blood Pressure measurement. Despite the relative simplicity of the technique, sphygmomanometers have obvious limitations regarding accuracy and tracking capability, especially crucial for hospital patients. In the most critical patients the invasive arterial line catheter must be used, which however poses serious risks for severe complications. Over the past decades, several attempts have been undertaken to develop an effective, accurate and reliable solutions to continuously monitor blood pressure in a non-invasive way. Hitherto, none of the solutions under development have achieved a massive market deployment. Major obstacles for the implementation of state-of-the-art solutions are related to their limited performance, resulting in poor accuracy in hypo/hyper tension episodes, influence of patient movements on the system response, and need for periodic and frequent recalibrations.ICARIA has developed a solution for blood pressure monitoring (ICA-100) based on a novel operating principle that allows obtaining an accurate diastolic and systolic Blood Pressure read-out. The ICA-100 has already been validated in healthy volunteers (TRL5). The technology is protected by two international patents, granting ICARIA freedom-to-operate.In the frame of this Phase 1 Project we aim to further develop our marketing strategy and financial plan. Besides, we aim to assess thoroughly the relevant regulatory and legal framework for the Project. After completing this feasibility study, we plan to develop and commercialise a certified device for Continuous Non-I
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Exosomes as microenvironmental cue for engaging mesenchymal stem cells in osteosarcoma progression'.

assistant: **Objectives**

Osteosarcoma (OS) is a very aggressive malignant bone tumor that develops primarily during childhood and adolescence. It is characterized by rapid growth, a strong tendency for recurrence and an extremely high metastatic potential. In the last three decades OS survival in the presence of metastasis has stagnated at a dismal 30%, clinical trials proved unsuccessful and no major breakthrough in the treatment of OS has been reported. To stop OS mortality, alternative therapeutical approaches urgently need to be explored. Studies into the molecular and cellular events underlying OS revealed complex and heterogeneous genetic alterations, which challenge the prospect of finding and exploiting an unique molecular driver underlying OS. Because OS onset occurs at sites of rapid bone growth during the adolescent growth spurt, microenvironmental factors and tumor stroma may have a defining role in OS development and progression. Surprisingly, the intercellular cross-talk between OS cells and components of the tumor stroma, in particular mesenchymal stem cells (MSCs), have been poorly investigated.Here I intend to demonstrate that tumor secreted vesicles called “exosomes” function as a key microenvironmental factor in OS progression by controlling tumor-stromal cells interactions. Specifically, we aim to explore whether MSC become pro-tumorigenic and pro-metastatic upon interaction with OS exosomes in bioluminescent mouse xenograft models. To identify the molecular signals (i.e. proteins and regulatory RNAs) in OS exosomes responsible for altering MSC behavior, we will employ state-of-the-art proteomics and deep-sequencing techniques. Finally, by means of functional assays we wish to discover the mechanisms by which OS exosome “educate” MSCs.The identification of and interference w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Systems Biology of Alcohol Addiction: Modeling and validating disease state networks in human and animal brains for understanding pathophysiolgy, predicting outcomes and improving therapy' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Alcohol addiction ranks among the primary global causes of preventable death and disabilities in human population, but treatment options are very limited. Rational strategies for design and development of novel, evidence based therapies for alcohol addiction are still missing. Within this project, we will utilize a translational approach based on clinical studies and animal experiments to fill this gap. We will provide a novel discovery strategy based on systems biology concepts that uses mathematical and network theoretical models to identify brain sites and functional networks that can be targeted specifically by therapeutic interventions. To build predictive models of the ‘relapse-prone’ state of brain networks we will use magnetic resonance imaging and neurochemical data from patients and laboratory animals. The mathematical models will be rigorously tested through experimental procedures aimed to guide network dynamics towards increased resilience. We expect to identify hubs that promote ‘relapse-proneness’ and to predict how aberrant network states could be normalized. Proof of concept experiments in animal will need to demonstrate this possibility by showing directed remodeling of functional brain networks by targeted interventions prescribed by the theoretical framework. Thus, our translational goal will be achieved by a theoretical and experimental framework for making predictions based on fMRI and mathematical modeling, which is verified in animals, and which can be transferred to humans. To achieve this goal we have assembled an interdisciplinary consortium (eight European countries) of world-class expertise in all complementary skills required for the project. If successful this project will positively impact on the development of new therapies for a disorde
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Network on ethnicity and women scientists' (NEWS) targeting Sixth Framework.

assistant: **Abstract**

The project concerns the position of foreign women scientists and women scientists from foreign origin (migrant or ethnic minorities) in the Member States of the enlarged European Union. The project wants to contribute to an increase of the knowledge base on women in science as well as to make visible and improve the position of foreign women scientists and those from ethnic minorities belonging to the European research workforce. It aims at investigating the situation of foreign women scientists and those from foreign origin pursuing scientific careers in the EU and at highlighting similarities and differences in their position in terms of equal opportunities.More specifically, the objectives of the project are:To investigate the situation in terms of gender and ethnic diversity in science careers in 8 European countries (Belgium, France, Germany, Italy, Portugal, Sweden,The Netherlands, United Kingdom) and one Eastern European candidate country for the EU entry (Bulgaria); To mobilise the foreign women scientists and those from ethnic minorities in order to produce a lasting impact in each country concerned around the issues of increasing their participation in science, improving their working conditions, ensuring equal opportunities and reinforcing the realisation of gender and ethnic diversity in science; -To build and develop a network on ethnicity and women scientists in the countries under investigation and connecting it to established national, European and international networks of women scientists; To promote exchange of experiences, good practices and policies in such a way that national and European research policies can be reinforced; To disseminate information on the role played by foreign women scientists and those from ethnic minorities in the developmen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Nanocomposite Materials Manufacturing by Ultrasonic Welding' (ULTRANANOMAN), addressing dissemination and exploitation.

assistant: **Impact**

Delivering the promise of nanotechnology to society for much-awaited products and jobs, hinges critically on manufacturing technology transfer to industrial production. This project introduces novel affordable, efficient and environmentally safe manufacturing of nanocomposite materials, by ultrasonic welding of foils with sandwiched nanoparticles. Research goals thus arise to study and control the material process-structure-properties interactions during nanocomposite fabrication and utilisation, by laboratory analysis, computational simulation and process control of materials for universal industry use. Training of postgraduate students and research experiences for undergraduates will be fostered, by thesis supervision, new curricula with laboratory exposures, and nanomanufacturing seminars and conferences. Outreach will benefit pre-college students and teachers, by nanotechnology modules, demonstrations and laboratory open house; industries by applied projects and student internships; women students by role models; and the public by hands-on exhibits, continuing education and web self-study.Although based at the University of Cyprus host, this Marie Curie project will be broadly shared across Europe, in collaboration with institutions in EC states and USA, by mutual visits, web/video-conferencing, meetings and student exchanges. The Chair initiatives will be pioneered by Prof. Haris Doumanidis, founding Director of Nanomanufacturing at NSF, Presidential Faculty Fellow of the White House, and ASME/National Academy of Eng. distinguished authority in thermal manufacturing at MIT, Tufts University and industry. This project will transfer his international excellence activities to Europe, and together with key expertise in Cyprus and abroad, will nucleate a signature Europ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Mathematics and Mechanics of growth and remodelling of bio-filaments' under Seventh Framework.

assistant: **Concept**

This project aims at developing a theory of growth, dynamics and mechanics of bio-ﬁlaments including branching processes. It will then be applied to a variety of physically and biologically interesting systems.At the mathematical level, the growth of biological ﬁlaments involves interesting aspects of both kinematics and dynamics of curves. A natural starting point for the modeling of bioﬁlaments is to consider them as thin elastic rods subjected to external constraints. The basic idea is to cross-sectionally average all stresses along the space curve representing the centreline of the rod. This leads to a set of equations, the Kirchhoff equations, relating averaged forces and moments to the curve’s strains (characterized by the curvatures, shears, and extension). These equations provide the starting point for much theoretical analysis and numerical modeling. They are valid for a large range of scales and have been used to model many different structures including DNA, vines and plants.Early work will be the basis for establishing a general and rigorous theory of growing elastic rods that we referred to as morphoelastic rods. Various microscopic mechanisms for the generation of intrinsic macroscopic curvature, torsion and twist will be studied. Furthermore, the initiation of branching points will be described. Simultaneously, we will consider various applications in life sciences to motivate these general theories. In particular, in collaboration with various biologists, we will model the growth of neurons and plants.""