RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'WORKFLOW INFORMATION SYSTEMS FOR EUROPEAN NURSING CARE'.

assistant: **Objectives**

In Europe, nursing services represent 40-60% of the national healthcare budget, yet the impact of nursing care on the total quality of care for patients has never been evaluated. The goal of this project is to exploit systematically clinical nursing data stored in electronic patient records for clinical and resource management. This will allow a shift from individual knowledge to knowledge-sharing, which will lead in the end to better patient care. The project uses a workflow information model in which the diversity of the patient population, the variability of care, patient outcomes and nursing resources are quantified and made visible. WISECARE meets the needs of many nurse managers in Europe dealing with questions of nursing workload and nurse staffing for better quality care.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Protective influence of mhc genes on diabetes in a tcr transgenic mouse model' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

In the NOD mouse, a valuable model for human IDDM, the diabetes susceptibility is linked to MHC II genes, but the mechanism(s) of influence at the T cell level are not yet clear. Using the established BDC2.5 TCR transgenic mouse line and making appropriate crosses into the B6, NOD and B6.H-2g7 background, 4 lines of mice could be obtained with homo- and heterozygous expression of the NOD MEIC H-2g7 or B6 MHC H-2b in the NOD or B6 background, respectively. The aim of this study is to investigate the protection mechanism(s) of the non-NOD MHC II Ab molecule on insulitis and IDDM. At first, two mice lines carrying knock-out alleles should be generates to confirm the direct role of the Ab molecule and to eliminate the contribution of non-transgenic TCRs. Furthermore, the T cells from the different mouse lines and the expression of MHC of MHC molecules in splenic antigen presenting cells (APSs)will be compared. Finally, the ability for these APSs to stimulate T cell proliferation and especially the influence on the Th1/Th2 balance should be investigated.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Design and Development of 3D Printed Force Transducers' under Horizon Europe.

assistant: **Concept**

Additive manufacturing (AM), as an advanced manufacturing technique, has the potential to transform the landscape of product development, manufacturing, and logistics, as well as increase sustainability in a variety of industries. Over the past ten years, AM, has gained widespread acceptance for producing various engineering and scientific components for research, commercial, and even medicinal uses. The aim of the project is to design and develop 3D printed force transducers. The specific objectives of the project are to contribute to the development of realistic concepts, realizing that transducers are of many sorts and configurations. The formulation of a model for extreme multi-physics situations is a significant goal of the work. The project has a strong multidisciplinary aspect, combining well-developed mechanics, material science, metrology, machine design, and computational analysis. This proposal includes both the transfer of knowledge to the host institution and the training of the candidate in new advanced techniques. This project is in line with the EU strategy for the United Nations Sustainable Development Goals.


**Keywords:** Accuracy,  Additive manufacturing,  Force transducer,  FEA,  Metrology,  Precision
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'STochastic Algorithm for Robust Guidance Analysis and Trajectory Estimation' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

We are approaching a new space age, where safety and cost reductions are key factors to achieve a more democratic space access. A crucial component of this new era will be represented by autonomous systems able to safely complete their mission despite a harsh and vastly uncertain environment, (for instance the atmosphere of Mars or the gravitational field of an asteroid). A disruptive example of autonomous systems is given by SpaceX’s rockets, which are safely reused, thus drastically easing human access to space.The current optimal trajectory generation process uses deterministic models. However, this approach is valid as long as the real system does not excessively deviate from its abstract model. When this happens, a (sometimes critical) loss of performance occurs, due to the uncertainties’ effects playing a major role in real-world scenarios.STARGATE has the groundbreaking goal to change how trajectories for autonomous systems are computed by including uncertainties in the design through their stochastic properties rather than simply assess their effect with a-posteriori validation. The proposed methodology will overcome the so-called curse of dimensionality, a so far insurmountable technological limit for these applications, by using a novel, scalable approach coming from the interplay of two new theories, Unified Unscented Transform and Kalman-Pontryagin Sequential Consensus Optimization. I will forge the theoretical formulation and a numerical framework accompanied by realistic applications (e.g., Six-DoF rocket landing, asteroid descent, and spacecraft rendezvous) to demonstrate the versatility of this brand-new methodology. Finally, I will move to a real-testing stage by using world-class testbenches available at DLR. With my team made of 2 PhDs and a Postdoc I
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Novel algae-based solution for CO2 capture and biomass production' (ALGADISK), addressing dissemination and exploitation.

assistant: **Impact**

The aim of the ALGADISK project is to develop a modular, scalable, and automatic biofilmreactor for Algae biomass production, with low operational and installation costs. Thereactor will be designed to capture CO2 from industrial emissions to produce high valueorganic products. In this system, algae will be grown both in an aqueous environment andon biocompatible surfaces, allowing for CO2 absorption from either the gas or liquidphase. This method will dramatically increase the efficiency of the reactor, and decreasewater requirements. Automatic and continuous harvesting of algae will be designed tooptimize CO2 uptake and biomass production. Adjusting the scale of the system will betrivial, as ALGADISK will have a modular design, and the installation’s footprint will beconsiderably reduced compared to technologies currently on the market. Design softwarewill be provided which, based on user input, will suggest installation parameters, performa cost/benefit analysis to calculate economic feasibility, and make predictions concerningthe environmental sustainability of the system. The proposed system will be specificallycrafted to meet the needs of European SMEs who are willing to produce algae biomassproducts from industrial emissions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Fostering local, beautiful, and sustainably designed regenerative textile and clothing ecosystems' (FABRIX) under Horizon Europe.

assistant: **Objectives**

The transition towards a more sustainable, digital, and inclusive economy in Europe requires a human-centred approach that combines digital and industrial technologies and which has an eye for spatial dynamics. However, there is a lack of integration between different disciplines and initiatives, resulting in missed opportunities for this transition. FABRIX aims to address this challenge by adopting an integrated approach to local and regenerative urban manufacturing, combining spatial design, developing opportunities for industrial symbiosis and circular manufacturing, and by value chain analysis and management. FABRIX will develop an innovative and interactive platform (MANTEL) that supports local value-chain management for more circular and regenerative urban manufacturing. FABRIX focuses on the textile and clothing sector (T&C) in Athens (Greece) and Rotterdam (The Netherlands). T&C is one of the most environmentally and socially unsustainable sectors. It is a priority in the European Green Deal, the Circular Economy Action Plan, and the Industrial Strategy. The core innovation of FABRIX’s research design and implementation is the entanglement of spatial and relational perspectives; perspectives that cannot be seen apart, but that in practice are mostly dealt with separately in policy and research, thus hampering significant progress. FABRIX allows for a pro-active co-created implementation and change of the observed suboptimal reality. FABRIX’s focus on the T&C sector, its innovative mix of research methods, its interactive, open-source digital platform of tools, and its capacity-building FABRIX Academy, will ensure the transferability during and beyond the research and innovation action to other places and other sectors dealing with similar suboptimization.


**Ke
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Studies of neurosecretion by remote control of exocytosis and endocytosis with ligt' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Optical switches are photoisomerizable compounds that allow to remotely controlling the activity of proteins, cells and entire organisms with light. These tools are revolutionizing research in biology with their high selectivity and spatiotemporal resolution. Here we propose to develop and apply optical switches to investigate the fundamental processes of secretion, exocytosis and endocytosis, in a way that is non-invasive, acute, and orthogonal to pharmacological and electrophysiological techniques. The optical control of exocytosis will be carried out by means of photoswitchable, Ca2+-permeable channels (LiGluR and Channelrhodopsin-2) which allow triggering vesicle fusion at single synaptic terminals. This procedure will allow studying vesicle release kinetics and the differences between synapses of the same neuron. The photocontrol of endocytosis will be carried out with: (1) inhibitory peptides of the clathrin pathway modified with an azobenzene crosslinker in order to photomodulate their structure and affinity, and (2) photoswitchable synthetic compounds based on chemical inhibitors of dynamin. Photomodulation of endocytosis in chromaffin cells and neurons will allow interfering with the internalisation of membrane receptors with an unprecedented spatial and temporal control. The use of photoswitchable inhibitors of endocytosis would allow for the first time to manipulate reversibly and with subcellular resolution, the vesicular trafficking of the endocytic pathway. In addition, these photoswitches could reveal how endocytosis regulates spatially receptor activation, controlling cell patterning and cell fate.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'A novel suite of technologies and an inexpensive platform based on Artificial Intelligence for remote access to live performing arts with an immensely improved feeling of presence' to be submitted under Horizon Europe.

assistant: **Abstract**

The vision of ACCESS is to create an integrated framework for remote attendance of (live streamed) performing arts that offers a stronger feeling of presence compared to existing live video streaming products. To this end, we will radically extend the latest advances in Deep Learning (DL)/Artificial Intelligence (AI), we will build upon leading industrial DL capacities, and we will integrate these into mature virtual reality (VR) technologies in a unique and innovative way. Specifically, ACCESS will develop a virtual environment, wherein users:1) Will be able to watch live-streamed video of performing arts, processed in real-time so that the video appears more focused on areas of the video that the viewer looks at. For instance, a TV director usually points the camera to the person speaking; however, a viewer may want to look at the reactions of another actor. 2) Will be embodied into virtual avatars and be able to interact with a virtual companion. The companion will support short discussions with the viewer, both chit-chat and provision of information related to the presented arts show. This may be able to happen during the live streaming, while waiting for it to start, or at the end of it. 3) Will be able to interact with the virtual personas of other attendants inside a virtual foyer.These three components offer a stronger feeling of presence when attending a live show online.To achieve this vision, ACCESS pursues an intersectoral secondment program that fosters knowledge exchange between academic experts and industrial partners in the cutting-edge technological fields of AI and VR. Additionally, the participation of an arts organization dedicated to supporting contemporary culture and digital art is crucial for the success of this project, both technically as well
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'OpenTox - An Open Source Predictive Toxicology Framework' under Seventh Framework.

assistant: **Concept**

The goal of the OpenTox project is to develop a predictive toxicology framework with a unified access to toxicological data, (Q)SAR models and supporting information. It will provide tools for the integration of data from various sources (public and confidential), for the generation and validation of (Q)SAR models, libraries for the development and integration of new (Q)SAR algorithms, and validation routines. OpenTox will attract toxicological experts without (Q)SAR expertise as well as model and algorithm developers. It will move beyond existing attempts to solve individual research issues, by providing a flexible and user friendly framework that integrates existing solutions and new developments.  OpenTox will be relevant for REACH as it gives risk assessors simple access to experimental data, (Q)SAR models and toxicological information that adheres to European and international regulatory requirements. OpenTox will be published as an open source project to allow a critical evaluation of its algorithms, to promote dissemination, and to attract external developers. Facilities for the inclusion of confidential in-house data and for accessing commercial prediction systems will be included.  OpenTox will contain high-quality data and (Q)SAR models for chronic, genotoxic and carcinogenic effects. These are the endpoints with the greatest potential to reduce animal testing. The impact of OpenTox will however go beyond REACH and long-term effects, because it will be straightforward to create models for other endpoints (e.g,. sensitisation, liver-toxicity, cardio-toxicity, ecotoxicity).  The proposed framework will support the development of new (Q)SAR models and algorithms by automating routine tasks, providing a testing and validation environment and allowing the easy addi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Trifluoromethylation under Photoredox Catalysis' (TRIFLU).

assistant: **Innovation**

Fluorine chemistry is critically important to advance a range of fields inclusive of medicinal chemistry, agrochemical chemistry as well as material science. In this context, there is a demand for new methods for the late stage selective trifluoromethylation of substrates that are not activated by the prototypical carbonyl group functionality. Such substrates require new catalytic manifolds to enhance reactivity and allow control over selectivity (regioselectivity, diastereoselectivity, chirality transfer, enantioselectivity). We propose to apply the concept of photoredox catalysis (visible light activation of transition metal complexes) for the trifluoromethylation of organosilanes and feedstock olefins.This study will include in depth understanding of  reaction mechanisms (this will feature cyclic voltammetric measurements and electrochemistry) and will generate a library of compounds, the properties of which  will be examined  for potential application in drug discovery (GSK). The project will be carried out by an applicant who has expertise in fluorine chemistry and who is proficient in mechanistic studies. The host will bring complementary knowledge in fluorine chemistry, catalysis and photoredox catalysis. An ongoing external  collaboration will add expertise in electrochemistry (Lyon). Upon completion, this project will contribute to  advance catalysis in Europe and beyond and will allow the implementation of long lasting  collaboration  between Oxford and the Shanghai Institute of Organic Chemistry in China.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Novel precision fermentation process to produce animal-free bioidentical ovalbumin' under Horizon Europe.

assistant: **Concept**

Eggs are critically important in the global food system due to functional and nutritional properties; yet the egg market and supply chains are in crisis due to cage-free requirements and avian flu. Onego Bio will make it possible to manufacture egg protein entirely animal-free. We developed a highly-scalable precision fermentation process using the patented Trichoderma reesei cellular-based production to produce animal-free ovalbumin. We produce bioidentical egg protein with cost parity and 87% lower CO2 emissions compared to traditional animal-derived eggs.Ovalbumin is the most important egg protein, responsible for the essential ingredient performance. This single protein ovalbumin can solve all current challenges in the egg market and supply chain.Our product, Bioalbumen provides the nutritional and functional upsides of egg protein, without the environmental, ethical and safety-related drawbacks. Our manufacturing method stabilises the food supply chain and increases food security.


**Keywords:** Bioproducts, Food technology, Precision fermentation, Egg protein
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Coastal and lagoon resource centre' (COLAR), addressing dissemination and exploitation.

assistant: **Impact**

Overall objective of COLAR proposal is to create an internationally sound coastal and lagoon centre in Lithuania as well as facilitate establishment of coastal research and education network in the southeast Baltic region. The objective could be achieved by using and widening the already existing collaboration between the Coastal Research and Planning Institute (CORPI) and scientific institutions in the EU, other NAS states and the northwestern region of Russia. Proposal comprises 8 work packages focused on scientific, educational and administrative development of the Centre as well as enhancement of linkage to the end-users. Proposed measures include establishment of International Advisory Board, twinning activities, opening of post-doctoral positions for EU nationals, thematic conference and workshops, international postgraduate courses and establishment of Coastal Resource Service Centre.