RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Controlling spin properties of molecules with quantum fields: ab-initio methodologies for spin polaritons' (QED-Spin) targeting Horizon Europe.

assistant: **Abstract**

The goal of QED-Spin is to build novel ab initio techniques to reveal effects induced by quantum fields on the spin properties of molecules.  Quantum computing and spectroscopic techniques are just two of the main fields that stand to benefit significantly from advancements in spin engineering; a field that is currently at the science frontier both for  experiments and quantum many body theory. In this project I will propose new strategies based on strong light-matter coupling to manipulate static and dynamical spin properties of molecules. The mission of QED-Spin is to explore, using advanced theoretical techniques, the phenomena that arise when quantum fields interact with the electronic and nuclear spins of molecular systems and their implications in chemistry, spectroscopy and spintronics. In particular the proposed techniques  will represent a significant step forward toward a better manipulation of molecular spin qubits used in quantum information and energy and memory storage. They will also increase our current possibilities of control on the photochemistry of molecular systems. The effects induced on the nuclear spins will bring to the formulation of a novel and more selective nuclear magnetic resonance technique. The developed theoretical and computational techniques will provide, differently from the previously applied model treatments, new tools to quantitatively simulate spin properties of molecules. Combination of cavity quantum electrodynamics and accurate quantum chemistry methodologies will form the basis for the development of novel tools to interpret and design spin properties. Coupled cluster theory, configuration interaction and density matrix renormalization group approaches will be used. I believe that the results of QED-Spin will build the founda
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Development and application of isotopic methodologies in environmental research' (1998-2002), addressing dissemination and exploitation.

assistant: **Impact**

A Marie Curie Development Host Fellowship is available at the Isotopic Methodologies and Application Research group of the Environmental Science Department of the Second University of Naples (Caserta,Italy). Physicists and ecologists are involved in multidisciplinary experimental research programs concerning the quantification of carbon fluxes and stores in soils and their role in global carbon cycles. Conventional mass spectrometry, laser spectroscopy and analytical techniques currently used in ecology research are employed. A graphitization line is also operational for the treatment of samples for 14C measurements at the accelerator mass spectrometry facility at the Physics Department of the University of Naples. Qualification of the applicants in the above experimental fields is sought, together with interest in the development of new experimental methods and numerical models.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'next-Generation Handling of  Optical Stray-light in Telescopes' (2021-2027).

assistant: **Concept**

In the ever-evolving realm of space instrumentation, the quest for excellence is endless. Scientists tirelessly pursue optical instruments that can capture the universe in unparalleled clarity. Over the years, instruments have improved through the introduction of innovative design concepts and manufacturing techniques, as well as with the use of better detectors. However, for the most demanding applications, stray light (SL) increasingly emerges as the primary limiting factor. SL must be minimized by design through optimal opto-mechanical layout and material selection. In the most challenging situations, this is however not sufficient and a post-processing correction is necessary to reach the scientific requirements. For that, SL characterization is conducted on-ground, to ensure that the instrument does not present any unexpected defect, and to provide kernels for the SL correction algorithms. However, the capabilities of SL characterization were stretched to their utmost extremes. Identifying defects is extremely complex and often impossible, and SL correction algorithms require SL measurement campaigns which are time consuming and subject to inaccuracies. To enable the development of the next generations of space optical instruments, a new paradigm is necessary. This is my long-term scientific objective and the heart of this project. In that frame, my objective will be to mature a new technology: the SL characterization by use of ultrafast time-of-flight imaging.


**Keywords:** stray light, optical testing, optical calibration, ray tracing, baffle, space instrument, ghost reflections, scattering, radiometric accuracy, high contrast imagers
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'WATER QUALITY AND SUSTAINABLE AQUACULTURE: LINKS AND IMPLICATIONS' (AQUAS), addressing dissemination and exploitation.

assistant: **Impact**

In the last years there has been a steady growth in the development of aquaculture farms due to the increased demand of cultured species for consumption. One of the by-products of aquaculture is the creation of specific environmental problems related to intensive production and unsustainable farm expansion, leading to a boom and burst behaviour of aquaculture industries. Examples are the increasing occurrence of toxic red tides and the consequent incidence of diarrhetic and paralytic shellfish poisoning in southern European countries in the early nineties, or the permanent alteration of natural habitats in Latin America. Therefore, aquaculture and local water quality (WQ) are closely linked. The large inputs of nutrients and chemicals and the release of wastes into the environment may favour toxic algae blooms and induce bottom anoxia and eutrophication, especially where the carrying capacity of the receiving domain is limited (e.g., bays and semi-enclosed waterbodies. In turn, low aquaculture producti on rates may result from the appearance and spreading of diseases propitiated by a poor WQ. This proposal will help to better structure" the understanding on the relationship between aquaculture and WQ, aiming towards the establishment of a set of aqua culture-related predictors for WQ. This is the soundest way to increase farm production and product quality in a sustainable manner, i.e., within the frame of a socially acceptable ICZM. This goal will be achieved by collecting and combining existing fie ld observations with available numerical simulations,"paving" the way for quantifying the relation between WQ and farm productivity. It will also allow the use of natural forcing mechanisms to increase or get the most out of the carrying capacity of the waterbody. The final
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Southern Ocean Carbon and Heat Impact on Climate' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The Southern Ocean regulates the global climate by controlling heat and carbon exchanges between the atmosphere and the ocean. It is responsible for about 60-90% of the excess heat (i.e. associated with anthropogenic climate change) absorbed by the World Oceans each year, and is also recognised to largely control decadal scale variability of Earth carbon budget, with key implications for decision makers and regular global stocktake agreed as part of the Paris agreement. Despite such pivotal climate importance, its representation in global climate model represents one of the main weaknesses of climate simulation and projection because too little is known about the underlying processes. Limitations come both from the lack of observations in this extreme environment and its inherent sensitivity to intermittent small-scale processes that are not captured in current Earth system models. The overall objective of SO-CHIC is to understand and quantify variability of heat and carbon budgets in the Southern Ocean through an investigation of the key processes controlling exchanges between the atmosphere, ocean and sea ice using a combination of observational and modelling approaches. SO-CHIC considers the Atlantic sector of the Southern Ocean as a natural laboratory both because of its worldwide importance in water-mass formation and because of the strong European presence in this sector already established at national levels, which allow to best leverage existing expertise, infrastructure, and observation network, around one single coordinated overall objective. SO-CHIC also takes the opportunity of the recent re-appearance of the Atlantic Sector Weddell Polynya to unveil its dynamics and global impact on heat and carbon cycles. A combination of dedicated observation, existing de
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'EuroMix' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Euromix aim to develop an experimentally verified, tiered strategy for the risk assessment of mixtures of multiple chemicals derived from multiple sources across different life stages. The project takes account of the gender dimension and balances the risk of chemicals present in foods against the benefits of those foods.Important concepts for this new strategy are prioritisation criteria for chemicals based on their exposure and hazard characteristics and evaluation of the role of mode of action in grouping chemicals into cumulative assessment groups. In-silico and in-vitro tools will be developed and verified against in-vivo experiments, with focus on four selected endpoints (liver, hormones, development and immunology) to provide a full proof-of-principle. The EuroMix project will result in an innovative platform of bioassays for mixture testing and refined categorisation of chemicals in cumulative assessment groups.New hazard and exposure models will be embedded in a model toolbox, made available for stakeholders through an openly accessible web-based platform. Access to the web-based tools will be facilitated by training. Criteria will be set and guidance will be written on how to use and implement the tiered test strategy. Dissemination and harmonisation of the approach within EU, Codex Alimentarius, and WHO will be achieved by involving a.o. WHO and US-EPA in the project and by the participation of experts playing a key role in helping establish international food safety policies.It is expected that the new mechanism-based strategy, the bioassay platform,  the openly accessible web-based model toolbox, and clear guidance on a tiered hazard and exposure test and risk assessment strategy  will boost innovation in the public and private sector, provide a sound scien
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Cortical Dynamics of Decision Irrationality'.

assistant: **Innovation**

Imagine that you choose a large house with a long commute over a small flat with a short train ride. Will the appearance of an inferior, thus irrelevant, alternative–a small flat with a longer train ride–make you revise your initial choice? Contrary to what theories in economics prescribe people typically reverse their original choice in the presence of an inferior option. Contextual preference reversals (CPRs) of this form are hallmarks of human irrationality. Such deviations from rationality have been described in numerous behavioural studies over the past decades. But what are the mechanisms that produce CPRs? And why do CPRs differ across individuals? I aim to answer these big open questions. Specifically, I plan to elucidate the brain mechanisms that mediate CPRs, from the level of neurotransmitters, to large-scale brain networks, to behaviour. To this end, I will combine, for the first time, three novel approaches: a model-based approach I developed for quantifying irrational decision-making in a physiologically tractable fashion; delineating the neural interactions underlying decisions with magnetoenecephalography (MEG); and pharmacological manipulation of these interactions. I will then use the MEG data to guide the development of a biophysically constrained mechanistic model of irrational decision-making. This model will be used to generate novel predictions about CPRs in the healthy brain as well as in several neurophysiological disorders. In sum, my research will tackle long-standing problems from the behavioural sciences with techniques from the life sciences, thus providing a deeper understanding of the limits of human behaviour. I will be thoroughly trained in advanced neurophysiological techniques in preparation for a career in the nascent field of “compu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Secretariat for the International Consortium for Personalised Medicine (IC PerMed)' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The potential of Personalised Medicine (PM) is to improve prevention, diagnosis and treatment of diseases by taking into account individuals' genotypes and phenotypes as well as other biomedical, life style and environmental data. In the last decade, significant advancements have been made especially for cancer or rare diseases. However, due to fragmentation and high upfront-investments the implementation of PM remains challenging, besides the various ongoing research and implementation actions on European, national and regional level. To overcome these hurdles, the International Consortium for Personalised Medicine (ICPerMed) is currently being initiated as a joint endeavour of the European Commission (EC) and more than 20 Member States. ICPerMed aims at aligning present as well as future efforts in all areas of PM by fostering international coordination of research and innovation funding. For this purpose, ICPerMed will develop and operate a European platform for collaboration between funders of PM research. It will promote an interdisciplinary approach to PM and generate policies, best practices, guidelines, and standards. ICPerMed secretariat will substantially contribute to the success of ICPerMed by efficiently coordinating all consortium activities, by implementing an effective dissemination plan and by assisting in the development of a sustainability strategy. By monitoring ongoing research funding activities in Europe and beyond, the secretariat will serve as the basis for evidence-informed allocation of research funding. ICPerMed secretariat will provide professional support in organising ICPerMed events and the meetings of ICPerMed bodies. In addition, ICPerMed secretariat will guide the dialogue with relevant stakeholders and initiatives. The organisational
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'New Exploration Technologies' (NEXT).

assistant: **Concept**

NEXT proposal has been compiled by a pan-European consortium, which consists of 16 partners from leading research institutes (3), academia (3), service providers (5) and industry (5). The members come from 6 EU member states (Fi, FR, DE, MT, ES and SE) and represent the main metal producing regions of Europe, Fennoscncian Shield, Iberian Pyrite Belt and Central European Belt. These economically most important metallogenic belts of the EU have diverse geology with evident potential for different types of new mineral resource. The mineral deposits in these belts are the most feasible sources of critical, high-tech and other economically important metals in the EU. The project consortium has also a vast international collaboration network, e.g. 50% of the Advisory Board members have been invited from outside EU. In addition to the variable geology, the vulnerability of the environment and the glacial sedimentary cover in the Arctic regions of northern Europe, and the thick weathering crust and more densely populated nature of the target areas in the Iberian and Central European belts influence the mineral exploration in different ways. The social conditions in potential benefits and challenges also vary. Therefore the new environmentally sound exploration concepts and technologies will be optimized and tested on diverse mineral deposit types.NEXT will develop new geomodels, novel sensitive exploration technologies and data analysis methods which together are fast, cost-effective, environmentally safe and socially accepted. Methods developed reduce the current high exploration costs and enhance participation of civil society from the start of exploration, raising awareness and trust.  Moreover, the reduced environmental impact of the new technologies and better knowledge ab
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Target identification and elucidation of the molecular mechanism of action of saponin vaccine adjuvants QS-21 (QS21Mech)', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Adjuvants are vital components of modern molecular vaccines that increase the low immunogenicity of subunit peptide and/ or polysaccharide antigens and potentiate the immune response. Despite their key role, the mechanisms of action of many adjuvants, including the clinically-relevant saponin QS-21, are poorly understood, which hampers the rational design of new, improved vaccine adjuvants.To address this gap and shed light into this fundamental biological mystery, the main goal of this proposal (QS21-Mech) is to develop new chemical probes to investigate the molecular mechanism of saponin adjuvants, one of the most potent and promising class of adjuvants. Using a multidisciplinary approach at the chemistry-biology interface, synthetic saponin-based photoaffinity probes will be chemically synthesized, followed by immunological evaluation for adjuvant activity in mice. The active saponin probes will then be utilized in biological/mechanistic studies to discover the putative molecular receptor of these adjuvants using a chemical proteomics approach. The photoreactive group will be used to cross-link the saponin molecule to the putative interacting partner, while the reporter group will serve as a tag for affinity-purification of the cross-linked adducts. Finally, the identity of the putative receptor will be resolved using MS-based proteomics analysis. The identification of the molecular target of the saponin adjuvants will provide unprecedented mechanistic understanding, facilitating the elucidation of their molecular mechanisms of action, which is of fundamental interest in immunology. This knowledge will enable the rational development of improved saponin adjuvants and optimal adjuvant-antigen combinations for vaccines against a broad range of diseases.