RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Catalyst development for catalytic biomass flash pyrolysis producing promissing liquid bio-fuels (BIOCAT)' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

Biomass flash pyrolysis is the most promising process for the production of renewable liquid fuels. Large-scale applications are not foreseen shortly, because of the high upgrading costs of the liquids to reduce major problems (e.g. polymerisation, high viscosity) for their effective handling and processing as a renewable fuel. Catalytic biomass flash pyrolysis (CBFP) is a promising and economical process combining pyrolysis and catalytic upgrading in the same reactor. Commercial catalysts were found inappropriate for CBFP leading to high water and coke yields. Development of tailored catalysts for CBFP within this project will substantially improve the liquids fuel quality (less water; higher heating values; increased content of hydrocarbons and valuable chemicals, ~30 wt % each) and facilitate their effective introduction to the EU energy balance.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Corticosteroid therapy of sepsis and septic shock', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

The use of corticosteroids in patients with septic shock is controversial. There is an urgent need for more transparency and a European harmonisation of standards of diagnostic testing and therapy . This project will develop three tools that make diagnosis and treatment of sepsis more beneficial:1 . a Europe-wide diagnostic testing system;2. a consensus statement of diagnostic criteria for adrenal insufficiency;3.recommendations for corticosteroid therapy in septic shock. Products are the result of three groups of activities:1. The compilation of empirical data by medical staffs in 40 centres of 15 countries in four European regions;2. An analysis of adrenal gland diagnostic test harmonisation and validation, analysis of immune interactions, and a benefit analysis of corticosteroid therapy in septic shock;3. A valorisation process that finalises the products with operational guidelines and initiates a process to refine the tools and keep them up to date. The work will be performed by consortium of experts in intensive care, infectious disease, microbiology, endocrinology and ethics.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'The Chemical Code of Cooperation, Conflict and Competition' (CHEMDOC).

assistant: **Innovation**

The cooperation displayed by social insects has intrigued evolutionary biologists since Darwin. However, the harmonious appearance of their societies hides many conflicts of interest that exist between individuals in the colony. Social insects are also perpetually engaged in competition over resources such as space, food and mating opportunities. The study of cooperation, conflict and competition in social insects continues to be instrumental in testing evolution and ecology theory. Social insects, particularly ants, mediate these three fundamental biological interactions via pheromones, but the precise mechanisms and evolutionary consequences of these chemical messages are just beginning to be understood. The purpose of the proposed work is to investigate the role of pheromones in cooperation, conflict and competition throughout the lifecycle of an ant colony. I will characterise the pheromones of reproductive ants and determine whether these substances signal an individual’s value as a mating partner (e.g. the quality of a male’s sperm, or a queen’s ability to resist disease) and allow mate choice. This research focuses on the least-studied form of competition in social insects: sexual selection and competition between males. I will also investigate the pheromones produced by queens in developing colonies. Queen pheromones are thought to signal fertility and elicit care from the workers (facilitating cooperation). The same chemicals may also inhibit worker reproduction (a potential conflict), but no previous studies have identified queen pheromones in ants and determined their effect on workers. The proposed research is highly likely to discover the first queen pheromone in any social insect apart from the honey bee. This research is highly multidisciplinary, utilisin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Post Taliban Afghanistan: The Future of Militancy in Pakistan', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The US withdrawal from Afghanistan in 2021 and the subsequent takeover of Taliban has reinvigorated militancy in the border region of Pakistan. The border region formerly known as a Federally Administered Tribal Areas (FATA) became home to domestic and international terrorist organizations such as Tehrik-i-Taliban Pakistan (TTP), Al-Qaeda, Afghan Taliban and Islamic Movement of Uzbekistan (IMU) after 9/11. FATA was used as a training ground for orchestrating terrorist attacks in Pakistan, Afghanistan, United States (US) and European countries. Domestically the terrorists unleashed an era of terror killing thousands of innocent people. They assassinated Pakistan's former Prime Minister Benazir Bhutto and shot Malala Yousafzai. They attacked schools, health facilities and banned polio vaccination. The 7/7 London attacks and New York attacks 2010 were planned by the TTP in the tribal areas of Pakistan. Pakistan’s security forces conducted military operations against the militants and militancy began to decline after 2016. However, the recapturing of Afghanistan by the Taliban in August 2021 has provided new energy to the militants fighting in the tribal areas. They are grouping. They are seeking alliance with international terrorist groups and can them refuge in the tribal areas. This project will investigate the re-emergence of TTP addressing the following key questions. What are the key factors responsible for the re-emergence of TTP in Pakistan? How the re-emergence of Pakistan Taliban can pose challenges for women in the area? How the alliance of TTP with international terrorist groups such as Al-Qaeda and IS-K can create challenges for global security? What are the policy options for Pakistan and the world to counter the re-emergence of TTP and its alliance with other
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'ERA-NET ON NANOMEDICINE' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Nanomedicine is the application of nanotechnology to medicine and healthcare. The field takes advantage of the physical, chemical and biological properties of materials at the nanometer scale to be used for a better understanding of the biological mechanisms of diseases at the molecular level, leading to new targets for earlier and more precise diagnostics and therapeutics. Nanomedicine, rated among the six most promising Key Enabling Technologies, is one of the most important emerging areas of health research expected to contribute to one of the strategic challenges that Europe has to face in the future: Provide effective and affordable health care and assure the wellbeing of an increasingly aged population.EuroNanoMed III (ENM III) builds on the foundations of ENM I & II, which launched 7 successful joint calls for proposals since 2009, funded 51 transnational research projects involving 269 partners from 25 countries/regions, and allocated € 45,5 million to research projects from ENM funding agencies. ENM III consortium, reinforced with 12 new partners  from Europe, Canada and Taiwan, is committed to fostering the competiveness of European nanomedicine actors taking into account recent changes in the landscape and new stakeholders and challenges, as identified in the SRIA in nanomedicine. The first joint call for proposals will be co-funded by ENM III partners and the EC. After the co-funded call, three additional joint transnational calls will be organized and strategic activities will be accomplished in collaboration with key initiatives in the field. ENM III actions focus on translatability of project results to clinical and industry needs.


**Keywords:** Nanomedicine,  Transnational research project, Diagnostics, Regenerative medicine, Research , Predective pers
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Development of advanced joining technologies for supermartensitic stainless steel line pipes (JOTSUP)'.

assistant: **Objectives**

The JOTSUP project will develop advanced welding technologies by using laser beam (LB), low vacuum electron beam (EB) and radial friction welding techniques, improve the pipe manufacturing efficiency as well as to fully exploiting the advanced properties of the new generation supermartensitic stainless steels and new joining technologies. Furthermore, it also aims to develop strength matching welding consumables (which are not available today) for this high strength grade steels, to improve structural behavior of the welded flow lines during the pipe laying (e.g. reeling) and service of oil and gas industry for transportation of unprocessed oil and gas in the North sea. The benefit of the project on the environment is anticipated via a reduced use of chemical inhibitors for preventing corrosion in gas transport and increased safety against failure. The JOTSUP project consists of 14 partners from six European countries.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'MUtual SOurces on Modern MEDiterranean Architecture: towards an open and shared system' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

The project aims at studying the feasibility of a platform easing access to sources and resources on modern (i.e. 19th and 20th c.) Mediterranean architecture within the framework of a EU-Med partnership (France, Italy, Tunisia). It is based on the observation that a wealth of architectural and urban forms of European origin and/or inspiration exists in the southern and eastern shore of the Mediterranean, and has attracted, in the last decade, a growing interest from scholars, conservationists and authorities alike (from both sides of the Mediterranean), as new objects for research as well as potential candidates for protection, conservation and enhancement.Recording, studying, listing and restoring an architectural asset that tends to be perceived as a shared heritage is representing a developing field of activity for different disciplines (art history, archaeology, architecture, information management, cultural heritage studies and management, planning...), with significant potential of growth in the coming decades. Providing specialised knowledge in this field is thus essential to the development of research, as well as for decision- and policy-making. This domain of investigation suffers however from uneasy access to relevant documentary data. Primary sources, as well as secondary, material on given buildings or urban areas of interest are particularly difficult to retrieve.The objective of this proposed SSA is to produce, through joint research and the assistance of a multi-disciplinary group of experts (art historians, archaeologists, archivists, information officers, data base technology and system-building specialists, cultural heritage managers), the prototype of the electronic and virtual means that can help bridging the data dispersion and limited availabilit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Advanced Analysis of Polymersome and Exosome Hybrids for Potential Application in Therapeutics and Diagnostics'.

assistant: **Concept**

Biological vesicles hold great promise as nano compartments for various applications such as drug delivery systems, therapeutics, and diagnostic tools but fundamental relationships between material properties and activity are not sufficiently understood to create new products for the benefits of the European society. The overall aim of USOME is to develop characterization approaches for these novel materials enabling proper functionalisation. In particular, this proposal focuses on the development of an entirely novel analytical approach for the analysis of emerging biohybrid vesicles. As model systems we indicate polymersome-hybrids and exosome-hybrids, representing a variation in structure in terms of stability, origin (synthetic/natural) and their hybrid counterparts (proteins/synthetic polymers). Two processes will be studied in detail (i) the encapsulation of proteins in polymersomes; and (ii) the modification of exosomes with proteins and polymers. As a result, advanced analytical methods for characterization of polymersome and exosome hybrids for potential application in therapeutics and diagnostics will be established. The key to this envisaged breakthrough is based on field flow fractionation technique coupled to multiple detectors for elucidation of the structural and compositional distributions in the biohybid systems. This highly topical research will be performed within the individual fellowship of a young, very talented, and curiosity-driven African researcher in a leading European research institute. The combination of his expertise in analytical techniques, the biohybrids formation knowledge of IPF and specific knowledge of the associated partners will enable significant scientific progress in the field and unlocks value for patients. Excellent, customiz
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Prenatal Stress Investigation in Cerebral Organoids: a multi-omics study at the level of single cells', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Mental illnesses affect 25% of the EU population and share increased disease risk through long-term changes to the stress hormone system. These are precipitated as adversities during early life, including the prenatal period. Given the role of stress in causing mental illnesses, it is imperative to learn more about the molecular mechanisms involved. Some progress has been made in elucidating the neurobiology of stress, but many questions cannot be addressed with current tools, which include animal models and 2-dimensional human cell culture systems. This proposal aims to establish 3-dimensional culture systems called cerebral organoids – stem-cell-derived tissues that recapitulate features of the human brain – as research models for developmental psychiatric disturbances. We will focus on glucocorticoids (GCs), some of the primary mediators of stress exposure on the organism, and use organoids as a model of early developing brain. Molecular mechanisms will be compared between ‘stressed’ and ‘unstressed’ conditions, by sequencing the transcriptomes of individual cells. Furthermore, since stress-related disorders are mediated through epigenetic mechanisms, the impact of elevated GC exposure on specific cell types in the cerebral organoid model will be quantified at the epigenome level. These novel and powerful techniques will allow us to deconstruct tissue heterogeneity, elucidating the fine molecular underpinnings of human vulnerability and response to stress. Comparing findings to evidence from longitudinal human cohorts of mothers and their babies who underwent stress during pregnancy will allow placement of findings into the clinical context. This research would pave the way for translation into clinical research, and expedite transitions from basic research to identi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Functional genomics of fission yeast', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

Applications are invited for Marie Curie post-graduate fellowships to visit the University of Sussex Fission Yeast Group for periods of 3-12 months, and use the resources of the Fission Yeast Functional Genomics facility. Libraries of temperature-sensitive and insertionally mutated strains are available for high-throughput screening. Graduate students from EU states outside the United Kingdom, or the associated states, will receive training in the relevant techniques; if appropriate, strains of interest may be characterized by advanced molecular biological and microscopic techniques. Informal enquiries (to j.armstrong@sussex.ac.uk) are invited from interested students in any of the eligible states. The University operates an equal opportunities policy, particularly with respect to gender and ethnic background.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Groundwater recharge in the Eastern Mediterranean - a comparative study on integrated evaluation techniques for groundwater resources along a hydro climatic gradient' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

The GREM Project has three main objectives :* quantification of natural recharge in four different hydro-climatic environments in the Eastern Mediterranean in Greece, Cyprus, Israel and Jordan;* comparison of the suitability of different methods for groundwater recharge estimation in the Eastern Mediterranean;* development of an integrated model for groundwater resources evaluation including water quality and water quantity.Expected OutcomeIn general, the study should help to improve and facilitate the evaluation of groundwater resources in the Eastern Mediterranean. In four case studies in Greece, Cyprus, Israel and Jordan, recommendations on the sustainable abstraction and use of groundwater will be developed for representative key areas.The groundwater potential will be assessed as a regionalized variable : this should improve the knowledge about the natural distribution of groundwater and its quality and enable refined planing, especially in dry areas. With the mixing cell model a tool will be further developed that allows the prediction of groundwater flow and quality for given scenarios. Finally, the comparative study should result in guidelines for the most suitable methods of groundwater recharge estimation and their range of applicability in the Eastern Mediterranean.The work will be carried out in selected study areas along a hydro-climatic profile through the Eastern Mediterranean region. The key activities are :* Field work on groundwater recharge within the four individual study basins using the main estimation techniques water balance, halogen profiles and flow mixing modelling.* GIS integration of the different methods. This part of the study aims at building regional databases on Geographic information systems for mapping and regionalization. Quantitativ