RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Extreme Cycle time Reduction of Injection Moulding Processes by using High Performance Injection Moulds and Moulding Processes (HIPERMOULDING)' under Sixth Framework.

assistant: **Concept**

The project aims to develop a common internet-based platform for SMEs from the construction sector to provide an effective combination of two general functionalities: (a) Customer Needs Management (CNM) System: an innovative decision making support system regarding the products characteristics, applications and other consultancy services for SMEs' customers applying the web-enabled dialogue", and (b) Knowledge Communities Support (KCS) System: a system for SMEs to support an advanced form of co-operation through the creation of Knowledge Communities of SMEs in CI. The system should support the integration, management and reuse of the area specific knowledge via a common knowledge base. The platform will be owned by associations, and will offer members a means to establish individual CNM systems and benefit from the KCS System. The system will be used within the Associations to collect and exchange the business area specific knowledge among the members (SMEs) in a form of essential expertise, reachable anywhere, at any time. Such a system applying the common knowledge base and KM tool will be a low-cost solution, affordable for SME community. It will satisfy SMEs' urgent need for a radical improvement of communication with customers and will offer an effective knowledge sharing with other SMEs as a base for further implementation of new co-operation forms. The system will be tested in project partner (and other similar) organisations from the CI. For a successful solution it is obviously necessary to establish a multidisciplinary S&T approach combining research activities in different areas, such as KM, particularly creation of the adequate ontology, effective forms of on-line interaction among customers and SME (web enabled dialogue with expert/technical advisor), as we
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Combining advanced numerical simulations and strong gravitational lensing observations to put new constraints on the nature of dark matter' (SLIDE) under Horizon Europe.

assistant: **Objectives**

The nature of dark matter is one of the most fundamental and striking open questions in modern astrophysics. Despite the success of the favoured Cold Dark Matter (CDM) model in explaining observations of structures on scales larger than 1 Mpc, in reality a wide range of dark matter models are allowed, motivated to varying degrees by particle physics assumptions, and the tension between the CDM predictions and observations on galactic and sub-galactic scales. A combination of simulated predictions and observational data is essential to enhance our understanding of our Universe and set constraints on dark matter from astrophysical phenomena. The primary goal of this MSC project is to generate transformative predictions by filling the existing gap between advanced hydrodynamical simulations in the standard cold dark matter model and the alternative dark matter field, where predictions for observations have been so far often derived from dark-matter-only simulations or simulations of very small samples. This will be achieved through (1) the creation of an innovative set of hydrodynamical simulations spanning a wide range of dark matter models and including the physics of baryons and (2) the integration with an efficient pipeline to produce realistic mock observations. These will allow me to (3) compare the properties of simulated and observed objects and derive the new accurate predictions of the combined effect of dark matter and baryons on a number of observables, focusing on the gravitational lensing signal. I will address a number of open questions, such as: is dark matter cold, warm or self-interacting? Will future lensing observations be able to exclude models alternative to CDM? Do these models reproduce the observed scaling relations for galaxies? What will ALMA, EL
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Unravelling paradoxes in regulatory T cell biology: the molecular basis for an mTOR-dependent oscillatory metabolic switch controlling immune tolerance and autoimmunity' (2007-2013).

assistant: **Concept**

Our group has been investigating how the nutrient/energy-sensing mammalian target of rapamycin (mTOR)-pathway affects the responsiveness of CD4+CD25+FoxP3+ regulatory T cells (Tregs). We have shown that Tregs have a high metabolic profile associated with the hyperactivation of the mTOR-pathway, which is responsible for the in vitro anergy of these cells. A transient mTOR inhibition with rapamycin, before T-cell-receptor (TCR)-stimulation, induced Tregs proliferation in the absence of exogenous interleukin-2 (IL-2). While a transient mTOR inhibition was necessary to allow Tregs to enter the cell cycle upon TCR-engagement, proliferating Tregs increased the levels of activation of mTOR to sustain their own expansion overtime. These data indicated that the metabolic state influences Tregs fate and the responsiveness to TCR stimulation in a dynamic/oscillatory fashion through the mTOR-pathway. The results also suggested a new mechanism of regulation between metabolism and immune tolerance in the Tregs in which mTOR could be activated under physiological conditions in response to changes of the energy status. In the current project, we intend to further dissect the relationship between mTOR oscillating activity and Tregs responsiveness. We aim to dissect the molecular and cellular events that govern the responsiveness of Tregs in vitro and in vivo, and address the associated apparent paradoxes: 1)Why Tregs have high proliferation in vivo but are hyporesponsive to TCR stimulation in vitro? 2)Why the current strategies to facilitate the in vitro expansion of hyporesponsive Tregs require high doses of IL-2 together with rapamycin, which is a strong inhibitor of cell growth and proliferation? The conclusion of the studies proposed in this application will unravel important questi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Diffusion of Ions in Cementitious Materials' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Durability and reliability of concrete infrastructure is a serious, large scale, financial and safety concern with an increasing scientific, engineering and economical focus. Although the interest for numerical modelling of cementitious materials and durability issues increases rapidly in recent years, a comprehensive knowledge on their fundamental processes is still lacking. The proposed project is interdisciplinary, bridging fundamental understanding of multiphase ionic transport in porous materials and durability based design of cementitious materials that combine computational materials science, chemistry, physics and engineering technology. The influence of the morphological effect and the level of water saturation on the ionic diffusion properties of hydrating cement pastes will be investigated using the TU Delft's HYMOSTRUC cement hydration and microstructure development model. The diffusive properties of the simulated microstructures will be analyzed by a number of developed numerical 3D network methods. These innovative numerical 3D network models will be coupled with another developed numerical code, called MultIDiff, to describe the multi-component ionic diffusion in concrete structures considering the time and space dependency of parameters. This project will advance the quality of European science, relative to the North America (USA and Canada) and Japan, in the field of numerical tools to predict durability of cementitious materials. As both institutions: the host’s, TU Delft and the fellows, University of Zagreb are actively involved in industry related projects to predict the service-life of new and existing concrete structures, the results of this project will find a direct industry application. The design based on a sound quantitative basis will make c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Low Environmental Footprint Biological Treatment Processes for Waste and Wastewater Treatment' (LEF-BIOWASTE), addressing dissemination and exploitation.

assistant: **Impact**

LEF-BIOWASTE focuses on the development, optimization and evaluation of innovative, low environmental footprint biological processes for the co-treatment of municipal wastewater and biodegradable organic waste (BOW). Waste and wastewater will be co-treated by an up-flow anaerobic sludge blanket (UASB) followed by a sequential batch reactor (SBR). Furthermore, an innovative autotrophic nitrogen removal (ANR) process of short-cut nitrification followed by ammonium oxidation by nitrite will be employed (i.e. Anammox process). Research shall focus on the effect of operating conditions on the system’s performance and particularly on the oxidation of ammonium to nitrite and the requirement for inhibition of nitrate formation as well as on the Anammox process. The Anammox bacteria are very sensitive and specific conditions are required for their growth in activated sludge processes. Furthermore, LEF-BIOWASTE will examine the fate and removal of targeted non-conventional and emerging pollutants. The work will be carried out by developing and operating a bench scale UASB-SBR-ANR and by operating an existing pilot scale UASB-SBR-ANR system. The environmental footprint of this system will be compared to conventional wastewater treatment processes by conducting a life cycle assessment. Furthermore, the system will be assessed using technical, environmental, economic and social criteria through a multi-criteria analysis tool.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'DIVA - science in a different voice' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

DIVA will last two years, and aims at improving gender equal opportunities in science through awareness and sensitisation activities. The general objective is supported by 3 specific objectives, namely: 1.To raise awareness of scientists on the existence of gender stereotypes and sensitise them through quarterly discussion groups in research centres. 2.To sensitise policy/decision makers on the waste of female talents in order to stimulate a debate favouring equal opportunities 3.To sensitise high schoo l female students in order to promote a friendly image of science. These activities will be jointly managed by a team of 7 between experts and technical staff coordinated by an equal opportunity Ambassador who has acquired - over the years - an indisputabl e knowledge, experience and expertise in the field of equal opportunities and gender mainstreaming in Science. The decision of the team will be backed up by an external Advisory Board composed by 3 experts. The following activities will be implemented in o rder to achieve the above mentioned objectives: Objective 1: Quarterly discussion groups in research centres and universities with scientists to enhance the debate on equal opportunities in science. Objective 2:  Organisation of two press confe rences  Dialogue strengthening amongst equal opportunities stakeholders Objective 3:  A video (DVD format subtitled in Italian and English) with 4-5 interviews to well-known Italian female scientists to be used during meetings with students. The project final activity is a conference to be held in Rome on june 2007 which will be participated by: journalists, policy and decision makers, students, researchers and 3 Ambassadors from other countries. The conference besides presenting the project activities will also be a Forum to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'A novel optical sensor platform for detection and measurement of contaminants in gas pipelines to protect critical infrastructure from disruption and damage - Linevu' to be submitted under Horizon 2020.

assistant: **Abstract**

Pipelines have formed an integral part of our Natural Gas transportation critical infrastructure for decades and their importance is growing, as resources reduce and new markets and demand open up. Liquid contamination in pipelines is a serious issue for safety, security, reliability of supply and commercially for gas supply and transportation companies. Existing technology is designed only to analyse dry gas. Liquid contamination damages the analysers and sample systems and there is no indication of the quantity of liquid present. Early detection of contamination is key and will result in the issue being dealt with before it becomes a commercial problem and most importantly an urgent safety or security issue.The Linevu system introduces a non-intruding vision system at various points in the pipeline in order to determine if a liquid is present in the pipeline, so that the correct course of action can be decided upon before it becomes a serious issue.Our goal is to embark on a phase 2 project in order to bring to market a novel pressurised window, containment system and vision system which can confirm the presence of liquid, while not interfering with routine “pigging” maintenance in the pipeline. The safety, economic and social benefits are numerous and the system would be retro-fitted onto any existing pipelines in the global supply network.At a time of great change in the global energy industry in terms of changing sources of gas and security of energy supply, we believe that this innovative technology will provide the EU with a real competitive advantage in the global energy supply market and oil & gas multinationals such as Exxon, Statoil, BP and Shell have already shown great interest in the concept.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Phenotypic plasticity and speciation in cichlids' (PlasticitySpeciation), addressing dissemination and exploitation.

assistant: **Impact**

Phenotypic plasticity is considered a catalyst for speciation through two alternative mechanisms: the Baldwin effect and genetic assimilation. Midas cichlids – Nicaraguan freshwater fishes where multiple species diverged in sympatry in crater lakes after colonization from larger source lakes – are the ideal model to study the influence of plasticity in speciation. The presence of trade-offs in the morphology of Midas cichlids’ pharyngeal jaw – a trophic structure used to crush hard food items which plastically modifies its size and shape when subjected to hard food – allows to generate specific hypotheses. In fact, according to theoretical models, in presence of trade-offs genetic assimilation is more likely than the Baldwin effect. I will use common garden experiments involving two Midas species from Lake Apoyo and the species from Lake Nicaragua (which acted as a source for Lake Apoyo) subjecting the fish to hard and soft diet treatments, that are nutritionally identically and only differ in their hardness. I will then measure the levels and directions of plastic response in each species/treatment using advanced geometric morphometric analyses and I will assess their transcriptional correlates using a combination of Illumina RNA next generation sequencing and RT-qPCR. I will, therefore, be able to test the following three hypotheses: 1. that the derived  populations from Lake Apoyo show lower levels of plasticity than source species (as expected as a consequence of genetic assimilation); 2. that the plastic response in the source population produces the same phenotypes found in natural populations of the derived species (as expected according to the “flexible stem hypothesis”); 3. comparing the results with published data from African cichlids, that the genes differen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Reconfigurable optical processing for training and execution of large scale neural networks' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

The goal of the ROPE project is to develop a re-configurable (programmable) large-scale optical computing platform specifically for the training of large-scale feed-forward multi-layer neural networks. Such networks are commonly exploited in systems where adaptive control and behaviour is required but where the system itself is not easily modelled using standard analytic techniques (i.e. where system identification is problematic). Training these networks is often difficult due to the commonly slow rate of convergence of the weights and the sensitivity of the system to the choice of initial conditions and the parameters of the learning rules. This results either in the choice of inappropriately small networks or the extensive use of a high-performance computer to effect the training. Rope proposes an alternative strategy which will exploit reconfigurable optical processing to implement the network during the training phase and which, because of its speed of processing and interconnect communication, will enable large nets to be trained effectively and which will allow the user to vary the initial conditions and learning parameters to get the best from the system.The approach will be to exploit newly-developed acousto-optic processing elements which enable a signal represented by an acoustic wave to multiply an incoming light signal. These elements can be organised either in a 1-D array or in a 2-D array and, because of their extremely fast processing speeds: as a result they are very suitable for the implementation of multi-layer perceptron-like nets. The acoustic signal, which represents the network weights (and also the neural connectivity pattern), is generated under the control of a conventional digital computer and, thus, allows both network re-configuration and ar
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Electrically Tunable Functional Lanthanide Nanoarchitectures on Surfaces' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Lanthanide metals are ubiquitous nowadays, finding use in luminescent materials, optical amplifiers and waveguides, lasers, photovoltaics, rechargeable batteries, catalysts, alloys, magnets, bio-probes, and therapeutic agents. In addition, they bear potential for high temperature superconductivity, magnetic refrigeration, molecular magnetic storage, spintronics and quantum information. Surprisingly, the study of lanthanide physico-chemical properties on surfaces is at its infancy, particularly at the nanoscale. To address this extraordinary scientific opportunity, I will research the foundations and prospects of lanthanide elements to design functional nanoarchitectures on surfaces and I will study their inherent physico-chemical phenomena in distinct coordination environments, targeting novel approaches for sensing, nanomagnetism and electroluminescence. Importantly, our studies will encompass both metal substrates and decoupling surfaces including ultra-thin film insulators and graphene. Nurturing from these studies and in parallel, we will focus on graphene voltage back-gated supports, thus surpassing the seminal knowledge on electrically-inert substrates and enhancing the scope of our research to address the overarching objective of the proposal, i.e., the design of electrically tunable functional lanthanide nanomaterials.The culmination of ELECNANO project will provide strategies for:1.-Design of functional nanomaterials on high-technological supports.2.-Development of advanced coordination chemistry on surfaces.3.-Rationale of the physico-chemical properties of lanthanide-coordination environments.4.-Engineering of lanthanide nanoarchitectures for ultimate sensing, nanomagnetism and electroluminescence.5.-In-situ atomistic views of electrically tunable materials a