RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Reaction robot with intimate photocatalytic and separation functions in a 3-D network driven by artificial intelligence'.

assistant: **Objectives**

Mimicking the chemical production of nature is a well pursued dream in the scientific community. Scientific progress is limited by the lack of efficient synergies among complex functions and by a much smaller research library than nature. CATART will explore new synergies in reaction robots that mimic nature in a much faster way. This will be achieved using H2O and CO2 as model substrates. We propose systems containing 3-D quantum dot networks with the ability to simultaneously harvest sun-light by luminescence, photo-catalyze substrates and separate products. These phenomena will be managed by artificial intelligence, leading to reaction robots that autonomously learn and instantly maximize productivity. The envisioned system will revolutionize the way chemicals are produced. The combination of expertise in photonics, machine learning, catalysis, organic chemistry and engineering from 5 academic, 1 research center, 1 SME and 1 industrial partner will enable a successful pathway into feasible reaction robots. CATART will contribute to a game-changing chemical technology, placing EU industry and society in a privileged situation to face future economic and environmental constraints.


**Keywords:** Chemical Technology, Robotics, Photonics, Solar fuels
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Chiral Organometallics for Asymmetric Synthesis' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Chemical processes (synthesis) that create new C-C bonds from simpler molecules are also hugely important as this is how chemical complexity is built up. In a synthesis starting molecules are used to build new molecules by means of various chemical reactions. Organic synthesis generally involves the reaction between two molecules a nucleophile and an electrophile. These are attracted to each other rather like opposite poles of a magnet and a chemical bond is created between them. One class of useful nucleophiles are organometallic reagents as they readily react with electrophiles to make new bonds. However, chiral organometallic reagents are very rare, but clearly if they could be easily prepared they would be extremely useful as they would provide a direct synthesis of a broad range of chiral molecules. We propose a unique method for generating configurationally stable chiral organometallics and then we will explore what classes of electrophiles they react with. Our method involves initially generating a nucleophile (bearing a group that also leaves during the course of the reaction) (an organometallic reagent) and reacting it with another nucleophile (an organometallic reagent) to create a new chiral organometallic. We believe that reactions of this class of nucleophiles with conventional and non- conventional electrophiles will open up a whole new area of synthesis and provide a step change in asymmetric synthesis that could have far reaching consequences. With this information we will then apply the new chemistry in the synthesis of biologically important molecules that are otherwise difficult to make. This will particularly highlight the power of the new methodology.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Proteome-scale programmable protein perturbation and induced proximity' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Programmable perturbation technologies such as CRISPR-Cas have transformed how we study biological systems by offering efficient and scalable methods to manipulate DNA and RNA, thereby linking genotype to phenotype. However, corresponding technologies for rationally manipulating all proteins have lagged behind, restricting our ability to connect proteotypes to phenotypes. Developing a programmable protein perturbation technology would be a breakthrough in the biomedical sciences, as it would facilitate the interrogation of biology and creation of medicines in fundamentally new ways. The overarching goal of this proposal is to develop and apply such a high-throughput programmable protein perturbation platform by combining tools and concepts at the intersection of gene editing, proximity-induced pharmacology, and pooled screening. Our preliminary work has already established a foundation for this, including successful demonstration of high-throughput prime editing–mediated epitope tagging and targeted protein degradation (TPD) as well as induced proximity between any two proteins of interest. In this proposal, we will build upon these advances by: 1) establishing a proteome-scale TPD platform and applying it to uncover the time-resolved human protein essentialome, 2) interrogating the interactions between hundreds of therapeutic target proteins and thousands of protein degradation effectors in order to identify new strategies for induced-proximity therapeutics, and 3) characterizing a therapeutic landscape of cancer cell reprogramming strategies in which the function of cancer-associated proteins are overwritten by an endogenous effector protein. This proposal introduces new technologies for high-throughput programmable protein perturbation and induced proximity, offering
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'European Infrastructure of Open Screening Platforms for Chemical Biology'.

assistant: **Innovation**

The EU-OPENSCREEN Preparatory Phase forms the basis for the construction and operation of a pan-European infrastructure of open screening platforms for Chemical Biology. EU-OPENSCREEN will bring together leading laboratories from 14 European countries covering all aspects of Chemical Biology from high-throughput screening with a dedicated compound library to assay development, chemical synthesis for hit-optimisation, bio-profiling and in vivo studies, as well as a central database, training for scientists and platform staff and dissemination activities. The infrastructure will be used by researchers from universities, research institutes and SMEs across Europe, who either have only limited in-house facilities or no access at all to such resources and expertise. The EU-OPENSCREEN infrastructure will keep Europe at the forefront of the biological and medical sciences and will stimulate industrial research and commercial exploitation.In order to prepare the creation of an efficient network of centres which provide users with optimal resources, the EU-OPENSCREEN Preparatory Phase will address the following issues:- A user-focused access strategy.- The physical infrastructure requirements.- Suitable data standards and the framework for a database to archive and make the results available to the scientific community.- A financial management plan for the construction and sustainable operation of the infrastructure in co-operation with national funding bodies.- The legal approach regarding intellectual property issues.- An appropriate legal and governance structure.- The development of a Chemical Biology education package to ensure adequate training of scientists and platform staff.- A central Chemical Biology information gateway in form of a website.- The dissemination of the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Sustainable Peace Building', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

SPBuild is created and developed by a solid and dynamic network of 11 institutions (EDEN Network for Peace and Conflict) with a proven commitment and capacity to deliver high-quality training in the rapidly developing field of Peace and Conflict research. These universities have undertaken joint research, published, and jointly created a European Doctoral Enhancement Programme on Peace and Conflict Studies. The aim is to provide high quality training and research on sustainable peace building, implying a good understanding of the cross-impacts of the necessary and interdependent peace building activities, especially the promotion of good governance, inclusive development and comprehensive security. The study is comprehensive and trans-disciplinary; it sees peace building as a complex dynamic process of change involving different sectors, levels and actors, and researches the interdependencies or cross-impacts between the diplomatic, political, economic, security, and humanitarian efforts made in post-conflict situations. Each of the 11 participants will belong to one or more of three research programme teams –good governance, comprehensive security and inclusive development. Researchers, upon choosing their research tracks, will be closely connected to one of the three teams and receive close professional and academic supervision. This project is based on the idea of participative governance", which reconciles social values with those of a market economy, defending the promotion of peace and economic and social development through the participation of all social agents and actors, including local communities, special interest groups and companies, the public sector and development agencies and the voluntary sector including arts and environmental organisations. The indu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Solidarity Lost in Implementation? Social Mobility and Belief in Meritocracy Shaped by School Choice Policies.' (EDUMERIT).

assistant: **Innovation**

Educational choices shape futures, influence life chances, and are among the most significant factors in social mobility. Despite political and academic consensus on avoiding early selection, inequalities in educational opportunities are on the rise, even in systems that aim for equity or discourage parental choice. Paradoxically, the belief that today’s educational opportunities are meritocratically earned is growing, reducing the demand for inclusive education.EDUMERIT aims to explain the policy feedback of school choice implementation by revealing its contextually embedded effects on parental experiences and fairness beliefs. It shows how varying exposure to educational selectivity and political-social constraints, shaped by stakeholders' discretion and discourses, result in discrepancies between real and perceived outcomes, as well as related fairness judgements.It breaks through the state of the art in studying policy feedback effects in shifting the focus from policy design to policy implementation, and from broader popular attitudes to parental fairness reasoning in school choice. It offers a bold new conceptualization to define under which conditions feedback effects in education result in the rising meritocracy beliefs at the expense of re-distributional demand. It sets out a comparative nested empirical design to reveal parental school choice experiences and related fairness reasoning by combining cross-European evidence with survey experiments, qualitative interpretive interviews and social media analysis in Estonia, Poland, and Sweden. EDUMERIT innovates by addressing endogeneity in education policy feedback effects and advancing a relational approach to fairness reasoning. It develops the role of ‘forward-looking’ social mobility in the broader fairness deb
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Info mobility services for safety-critical applications on land and sea based on the use of integrated GNSS terminals for needs of OLYMPIC cities' (1998-2002).

assistant: **Innovation**

The overall objective of INSTANT OLYMPIC " is the setting up, validation and demonstration of three pilot projects based on the EGNOS System Test Bed in close integration with emerging technologies with the view to develop a pre-operational service provision:Pilot1: Rome, Land/urban Fire Sector,Pilot 2: Athens, Sea/ maritime confined waters, personal outdoor recreation,Pilot 3: Athens, Land/semi-urban Personnel security.The Project addresses mostly safety of life applications on land and sea, thus issues relevant to societal needs and specific operational needs arising in Olympic cities. All applications introduce a unique opportunity for EGNOS/Galileo and provide an add-on layer over existing infrastructure in terms of required accuracy, integrity and/or guarantee of service. The Project is based on industrial partners with high expertise in relevant technology field: digital mapping, mobile/satellite communications and software development."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Joint implementation for international emissions reduction through electricity companies in the european union and in the central and eastern european countries ('JOINT')' in the context of a Fifth Framework call.

assistant: **Objectives**

Joint Implementation (JI) has been defined in the Kyoto Protocol as one of the major 'flexible mechanisms' by which to tackle issues of climate change under the United Nations Framework Convention on Climate Change (UNFCCC). The primary challenge to initiate Joint Implementation at present is the lack of well-defined framework, either at an international or a national level, by which to identify and invest in qualified projects. The proposed project will bring electricity & CHP companies from Norway & the EU whit the five Accession States of Central & Eastern Europe to identify projects, set out the necessary framework for JI, undertake baselines, develop feasibility & marketing studies, & develop the financial framework for JI. Key government & NGO stakeholders will be involved at all stages to ensure all steps are in place for JI to be undertaken.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Development of a novel therapeutic HIV-1 vaccine: Horizontal gene transfer by using apoptotic HIV-1 DNA containing activated T cells' (2002-2006) under Sixth Framework.

assistant: **Objectives**

The overall objective for this multidisciplinary consortium is to transfer to the clinic our basic discovery that genes can be horizontally transferred to neighbouring cells by uptake of apoptotic cells. Our goal is to develop a therapeutic HIV-1 vaccine based on this technology. Apoptotic cells can be a good antigen delivery system by utilizing the body´s own natural mechanisms for transfer of DNA and proteins to antigen presenting cells (APC). Normally during HIV-1 infection this system is hindered by multiple mechanisms. We therefore envisage using this system during periods of low viral replication achieved by antiretroviral treatment. Hence, we will immunize already infected individuals who have received a limited period of antiretroviral treatmen t with either autologous apoptotic HIV-1 infected cells (AutoCell-HIV) or allogeneic apoptotic HIV-1 pseudovirus containing cells (AlloCell-HIV). The advantages with the present technology are; i)Antigen is targeted to the APC where it is expressed a for long time period. ii)In a mouse model broad cellular and humoral immune responses are generated after immunizations using this strategy. iii)The ¿vector¿ i.e the apoptotic infected cell, is capable of activating dendritic cells leading to stimulation of T cells. iv) The therapy is individualized and contains viral sequences from the patients own virus. v) HIV-1 genes and antigens are transferred to APC in a milieu devoid of viral replication vi) We immunize with apoptotic cells directly and hence do n ot require culturing of dendritic cells, which would be more cumbersome and therefore more difficult to implement in the developing world. We will perform safety and immunogenicity studies in macaques. We will optimize techniques for production of AutoCel l and AlloCell in a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Towards An Accurate Measurement of the Lifetime of Ultracold Neutrons Suspended in a Novel Fully Magnetic Trap' under Horizon Europe.

assistant: **Concept**

The Standard Model (SM) of Particle Physics predicts the free neutron lifetime, τn, as a function of only two input parameters with high precision. Recent theoretical progress now provides a SM description of neutron decay at the 10−4 level. My project, NuLife, will enable a future measurement of τn with 0.1 s accuracy to test these SM predictions at the same unprecedented level through the pioneering development of a novel, large-volume, and deep magnetic trap. Previous measurements with a material trap confirm that at least 200 times more ultracold neutrons (UCN) can be stored in such a deep magnetic trap, compared to our proof-of-principle setup τSPECT, when connected to the high-intensity UCN source of the Paul Scherrer Institute, Switzerland. My team and I will boost the statistical precision of the future experiment τSPECT2 by developing a novel phase-space matching beamline to maximize the transport of UCNs from the source to the trap. Complementary, we innovate large-scale hardware components required to fully exploit the superior control of systematic bias effects achievable in a fully magnetic trap and mandatory to determine τn with 0.1 s accuracy. My measurement will provide a high-precision test of the structure of the weak interaction which governs countless phenomena e.g., hydrogen fusion in stars and the radioactive decay of neutrons and nuclei. In theory, a much richer structure is allowed than yet experimentally observed: But nobody knows why Nature is as simple as it is! Tiny experimental departures from the SM prediction may hint at physics beyond the SM (BSM). Through its unprecedented accuracy on τn, my future experiment τSPECT2 will help to resolve experimental tensions in precision neutron decay observables and will enable high-sensitivity searche
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Building and district thermal retrofit and management solutions'.

assistant: **Innovation**

The 20% primary energy consumption reduction targets set by the European Energy Efficiency Directive (EED), published in 2012, call for effective and wide-scale building heating and cooling systems upgrade strategies. These will be successful only if they base upon the right combination of technology innovation, industrial commitment and building owners awareness.In line with this statement, THERMOSS proposes an industry-focused, innovation-intensive approach to ease and foster the introduction of cutting-edge heating and cooling technologies for building energy retrofitting at European level, targeting residential buildings and buildings connected to District Heating and Cooling (DHC) networks.The aim of THERMOSS is to define a set of retrofitting heating and cooling packages based on cutting-edge, high-potential, market-ready technologies that are connected together thanks to an open ICT platform for smart energy management at building and district-level. The THERMOSS technologies have been picked out from the catalogs of prominent European industrial players, Bosch, Veolia, Exergy, Schneider Electric taking into account business profitability, energy efficiency and potential for large-scale deployment. They will be tuned, combined and sized as part of the project thanks to dedicated tools, to optimize their joint impact. THERMOSS advocates a geo-clustered approach to the definition of these packages, in order to increase the impact of the solutions with respect to specific climatic conditions and – when applicable – specific National policies (e.g. fiscal incentives) and regulations. The THERMOSS packages and the platform will be thoroughly demonstrated in seven experimental and demonstration sites, covering all the dimensions highlighted by the call: residential bui