RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Cohomology, Geometry, Explicit Number Theory', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The aim of COGENT is to develop, analyze and apply efficient algorithms in three core areas where computer algebra plays an important role: Cohomology, Geometry and Explicit Number Theory. These will have applications to a broad range of mathematical problems, and will touch as well upon related topics like cryptography and quantum computing. Such applications of mathematics are expected to have a wide-ranging impact on economic and societal problems. Recent years have seen a plethora of high-flying projects and a dazzling variety of applications of methods in computer algebra. One of the emerging challenges is to combine ideas of different areas of computer algebra, to share expertise between them, and to educate young researchers in theoretical and practical methods with a focus of transferring knowledge and training software development skills. COGENT provides an  innovative training program to facilitate this and has ambition to stimulate interdisciplinary knowledge exchange between number theorists, algebraists, geometers, computer scientists and industrial actors facing real-life challenges in symbolic computation in order to bridge key knowledge gaps. This will address the urgent need for computer assisted investigations of several longstanding conjectures in mathematics, and EU industry’s need for workers with an advanced  mathematical and computational skill set. Not only do we expect to merge the best known tools for these purposes   with innovative approaches and ideas to extract previously inaccessible cohomological information of the underlying arithmetic groups, but we also anticipate finding new hitherto unknown concepts as we intend to enhance the currently available data pool by a whole order of magnitude. The latter will allow the researchers to find h
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'SOCIO-ECONOMIC AND CLIMATE AND ENVIRONMENTAL ASPECTS OF PALUDICULTURE' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Paludi4All aims to understand the socio-economic, climate and environmental aspects of paludiculture, thereby holistically assessing the potentials for climate change mitigation, environmental protection and creating jobs and income in rural areas, as well as identifying innovative solutions for upscaling paludiculture in Europe. This will be achieved through Paludi4All’s interdisciplinary, co-creation-based systems approach that addresses the farm-, value chain-, and market levels and the governance context shaping these levels.Paludi4All supports the paludiculture sustainability transition through enhanced understanding of economic implications of paludiculture for farms and society, creating a comprehensive market perspective on paludiculture, speeding up the development of paludiculture and improving knowledge on the paludiculture potential and environmental impacts. Paludi4All endeavours to contribute significantly to the expected outcomes of the work programme. By enhancing the understanding of paludiculture systems, supporting the EU approach to carbon farming, and exploring innovative solutions, we align with the broader goals of the European Green Deal, the EU biodiversity strategy, and the Destination's impact related to efficient monitoring, assessment, modelling, and decision-making support systems for climate change mitigation and adaptation policies at European and global levels.


**Keywords:** paludiculture, socio-economic, climate mitigation, environment
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The role of dna replication factors in the establishment of cohesion between sister chromatids' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

Ms Armelle LENGRONNE is a graduate student in my laboratory in Montpellier, France. She got her higher education from University Pierre & Marie Curie in Paris, then did her Diploma work with Dr. C. Jackson at the CEA in Saclay, on intracellular trafficking in yeast. She was one of the best rated student there, and as such, obtained a competitive PhD fellowship from the French government. I was delighted when she decided, in the fall of 1998, to join my laboratory for her thesis work. I know Armelle quite well as I interact with her on a daily basis. She is a very talented person, determined, well-read and critical of her own results, which are all attributes of a promising young scientist. Within short time. Armelle developed a series of techniques to monitor DNA replication globally and locally using BrdU incorporation in yeast cells (Lengronne et al. 2001. Nucl. Ac. Res. 29:1433). This paper is important as it contains the groundwork that paves the way for understanding the dynamics of chromosomes duplication. Armelle then used these techniques along with others to show that yeast cells lacking the cyclic-dependent kinase (CDK) inhibitor Sic1 initiate DNA replication from a reduced number of origins and, as a consequence, progress more slowly through S phase. Like its mammalian counterparts p21 and p27, the CDK inhibitor Sic1 is important for maintaining genomic integrity. Armelle discovered that sic1Delta mutants fail to partition sister chromatids properly, probably as a consequence of perturbed replication, and frequently lose or rearrange instability in mitosis by altering the number and/or positioning of replication origins. This work is now submitted, Armelle being first author. Another publication which describes the consequences for mitosis of altering the dyn
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'A Personalised Integrated Care Approach for Service Organisations and Care Models for Patients with Multi-Morbidity and Chronic Conditions' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The vision of the PICASO project is that it will become a Europe-wide Continuum of Care service platform that:will improve cooperation and exchange of knowledge between professional caregivers in health, rehabilitation and social care domains and actively include patients and their relatives in the integrated care settings thus supporting patient empowerment and self-care;will bring about improvements in health outcomes, daily activities, and quality of life of older persons with multi-morbidities by personalising care management programmes to specific characteristics of the patients' profiles and support adherence to care plans at the point of need;will reinforced medical knowledge and create new care models for management and treatment of patients with multi-morbidity conditions;will allow more cost-effective care management through increased skills and collaboration of care professionals and more automated and efficient workflows, which eventually will lead to better health outcome and a reduction in hospitals admissions, and thus contributing significantly to the sustainability of health and social care systems in Europe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Energy-aware enterprise systems for low-carbon intelligent operations' (ARTISAN), addressing dissemination and exploitation.

assistant: **Impact**

The ARTISAN project envisions significant reductions (at least 10%) in energy consumption and CO2 emissions of the European Textile Industry by integrating data-capturing technologies, process-based energy measurement and real-time optimization of operations.It will provide enterprise management systems with services for monitoring and operational decision making, available at each supply chain partner, and, additionally, trading services for energy and carbon permits forging collaboration across supply networks.Relying on a service-oriented architecture and data capturing through sensors and energy metering devices, expected achievements and technologies to be used of ARTISAN include:- an information infrastructure, enabled by AUTO ID, WSN or other hardware components, for efficient capture, storage and communication of energy consumption data;- energy performance indicator structures and services for the textile industry;- services monitoring, reporting and analyzing energy performance per process;- real-time optimization algorithms for planning and scheduling of supply chain processes and enterprise operations in terms of cost reductions and minimum consumption of energy;- tools for evaluating overall energy efficiency based on productivity assessment of processes and implicitly of products;- intra- and inter-organisational services for energy consumption forecast and trade of energy and CO2;- a layered architecture interconnecting the modules in a seamless way, enabling interoperability both internally and among supply chain partners.<br/>Field trials based on representative use-cases drawn from the European textile industry will demonstrate the functionality of the modules and the interconnections in a real context.Hence, each company is encouraged to become an ART
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'A Treatment-Oriented Research Project of NCL Disorders as a Major Cause of Dementia in Childhood' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The DEM-CHILD project focusses on the main cause for childhood dementia in Europe, the neuronal ceroid lipofuscinoses (NCLs). The NCLs are neurodegenerative diseases characterized by dementia, blindness, epilepsy and physical decline leading to an early death of the patients. Since no cure is currently available, these disorders represent a serious social, medical, and economic challenge.To date, eight NCL genes have been characterised. There is evidence suggesting that further gene loci remain to be identified. NCLs are under-diagnosed in many countries around the world as there is an overall lack of research, early diagnosis, treatment and expert availability. Furthermore, due to their broad genetic heterogeneity it is difficult to collect large numbers of genetically similar patients. As such, large therapeutic studies required for advances in treatment are difficult to initiate. The DEM-CHILD project will combine the expertise of (i) recognized European research teams with (ii) high-technology SMEs, and will (iii) collaborate with Indian experts on the following objectives:(1) High-technology SMEs will develop innovative cost- and time-effective testing and screening methods for all NCLs in order to ensure early diagnosis and thereby prevention.(2) DEM-CHILD will collect the world’s largest, clinically and genetically best characterised set of NCL patients in order to study disease prevalence and precisely describe the natural history of the NCLs leading to the development of an evaluation tool for experimental therapy studies.(3) Novel biomarkers and modifiers of NCL will be identified to support the development of innovative therapies.(4) Focussing on the development of therapies for NCLs caused by mutations in intracellular transmembrane proteins, two complementa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Mobility, Ubiquity and Security for small Devices' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Through their global, uniform provision of services, and their distributed nature, global computers have the potential to profoundly enhance our daily life. However, they will not realize their full potential, unless the necessary levels of trust and security can be guaranteed. We aim to develop the technology for establishing trust and security for the next generation of global computers, using the Proof Carrying Code (PCC) paradigm.The essential features of the \mobius security architecture will be:- innovative trust management, dispensing with centralized trust entities, and allowing individual components to gain trust by providing verifiable certificates of their innocuousness; and- static enforcement mechanisms, sufficiently flexible to cover the wide range of security concerns arising in global computing, and sufficiently resource-aware and configurable to be applicable to the wide range of devices in global computers; and- support for system component downloading, for compatibility with the view of a global computer as an evolving network of autonomous, heterogeneous and extensible devices.The PCC paradigm is known for decentralized trust management, but has generally been restricted to simple safety properties, and to monolithic, non-distributed applications. We shall pioneer the first PCC framework applicable to global computers, and the first to allow enforcement of functional properties as well as advanced security properties. We shall extend the two technologies that enable PCC- type systems and program logics-to allow enforcement of more advanced security properties, and combine them in hybrid certificates to be checked through type checking together with proof checking. To maximize the impact of our work, we will focus on Java-enabled global computers. Thi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'EU eHealth Interoperability Conformity Assessment Scheme' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

EURO-CAS, European eHealth Interoperability Conformity Assessment Scheme aims at maintaining and developing the adoption and take-up of testing the interoperability of ICT solutions against identified eHealth standards and profiles defined in the eHealth European Interoperability Framework (eEIF). The key deliverable is a sustainable Conformity Assessment Scheme (CAS) for Europe. Based on recommendations of the Antilope project and the state-of-art in interoperability testing in eHealth, EURO-CAS is committed to putting in place an operational CAS based on ISO/IEC 17025 that will meet the interoperability requirements of European eHealth projects as well as national and regional eHealth programs. This will allow testing the interoperability capabilities of products and services for a single digital market in eHealth in Europe in line with the Digital Agenda for Europe and based on international profiles and standards. The project will gather a multi-disciplinary consortium of high-level expertise, including organizations focused on implementing international standards as well as industry stakeholders and healthcare providers that will 1) review the state of the art of existing interoperability CAS, 2) collect the requirements and needs from cross border, national/regional levels, 3) establish the CAS for Europe with implementation guidelines and governance, 4) propose business models for the CAS for Europe, 5) validate results and foresee national/regional adoption, 6) inform and educate eHealth stakeholders and motivate industry and projects to participate in a European accreditation process. The CAS for Europe will provide a comprehensive framework completing the eEIF and aligned with the international CAS. Its flexibility will allow better sustainability and harmoniz
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Genomics of Cardiomyocyte Signalling to Treat and Prevent Heart Failure' (EUGENEHEART).

assistant: **Innovation**

EUGeneHeart will develop new approaches to prevent and treat heart failure through analysis of the genomics of signalling. Our strategy is based on the hypothesis that beneficial and maladaptive forms of hypertrophy exist and that heart failure is frequently preceded by maladaptive hypertrophy. We will dissect both adaptive and maladaptive signalling in hypertrophy to identify beneficial and maladaptive components of signal transduction in hypertrophy and heart failure. The EUGeneHeart consortium forms an extremely integrated project comprised of six major tasks. In Task 1, murine models will be analysed (phenotyped) in an integrated matrix approach: Wildtype mice will be subjected to pressure overload, myocardial infarction, and chronic exercise, genetically modified mice with a beneficial response to these stressors will be compared for differences in signal transduction. Task 2 identifies new players in different forms of hypertrophy and failure using screening techniques including proteomics and microarrays, forward and reverse genetics in drosophila and zebrafish, validation in murine models and patient cohorts. Task 3 exploits knowledge generated in the first two tasks and translates knowledge on existing pharmacological interventions to generate new candidate drugs in close involvement of SME's. Candidate small molecules and molecule libraries will be tested in a successive developmental platform. This will lead to patent filing, licensing strategies and to phase I and II clinical trials. Task 4 contains specific questions related to sex differences and to signalling in hypertrophy. Our approach takes account of national research activities and recruits knowledge, patients and tissues at a European level.Task 5 includes a training initiative and Task 6 contains t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Regulating plant quality by controlling xylem vessel dimensions during xylogenesis (XyloDimens)' (XyloDimens).

assistant: **Concept**

Many quality aspects of plants and plant products directly or indirectly depend on integrated import of assimilates and water during growth. Besides dry matter production and partitioning within a plant, plant-water relationships strongly influence growth, plant form and various quality aspects of plant products. Plant water relations are strongly influenced by the hydraulic properties of the vascular xylem, which are directly related to the dimensions of xylem vessels.Crucial quality aspects, such as for instance the ability of cut flowers to recover from embolisms in the vascular system at the start of their post-harvest vase-life are directly linked to the properties of xylem vessels. Dimensions of xylem vessels may differ with genetic background and are influenced by environmental conditions during growth. Xylem dimensions are therefore important for production and quality control.However, vascular patterns are robust once they are formed. Therefore actual control of xylem properties should take place during vessel formation (xylogenesis). Control (or manipulation) of xylem vessel dimensions by environmental factors during growth could be a way to improve quality of e.g. tomatoes or flowers. The final step in formation of tracheary elements (TEs) formation is programmed cell death (PCD, which can be regarded as a decision point determining vessel dimensions. PCD is an active process in which a cell suicide pathway is activated resulting in controlled disassembly of the cell.Most studies on cell death during xylogenesis have been done in Zinnia elegans. Cell death in Zinnia is precisely timed. At a specific time during formation of the secondary wall, the large central vacuole ruptures releasing a blend of hydrolytic enzymes into the cytoplasm. We will investigate th