RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The sedimentary environment of deep-water Corals: characterisation of a fragile marine habitat in need of conservation' (SEDCORAL).

assistant: **Concept**

Deepwater corals, such as Lophelia pertusa, are found on fascinating mound structures along the European continental margin, where they create rich ecosystems. However, several reefs appear to be damaged by deepwater trawling, and need protection.The Darwin mounds in the N Rockall Trough are the first to be protected through EU emergency measures under the Common Fisheries Policy (Aug. 2003). The province is awaiting the status of 'Special Area of Conservation', to be designated by the UK government under the Habitats Directive.However, the factors influencing the distribution of deepwater corals are not well known, and the exact processes governing their growth and development are not clear. In order to support conservation measures, a better insight in these habitats is necessary. The aim of the project SEDCoral is to provide a detailed characterisation of the sedimentary environment of deepwater corals.The study will consist of the detailed documentation of the Darwin mounds and a second province of small coral mounds in the area, chosen for comparison. Focus will be placed on the sedimentological characteristics of the coral environment. The information will be integrated in a GIS database, and the results communicated towards scientific and non-scientific end-users.The project will be embedded within the FP6 IP HERMES. The issues will be tackled through the integration and detailed interpretation of existing data, and the acquisition of new specific information using high-level technology such as ROV observations and well-positioned sampling. The project outcome will reinforce European excellence in the fields of deepwater corals and continental slope sedimentology.Through the project, the researcher will obtain training at a top-class research institute, which wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Neuronal regeneration after cerebral ischemia and trauma' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The Research Institute for Applied Neurosciences (FAN) is going to establish in vitro and in vivo models of neuroregeneration. Therefore, we are seeking two young scientists with proven records of expertise in cell and/or developmental biology, and preferably, in neuronal stem cell technology. Both candidates should have at least 4 years of postgraduate research experience. A knowledge of pathophysiological mechanisms leading to neurodegeneration following brain ischemia (e.g. stroke and trauma) is desired but not necessary. In particular we are interested in the following competence: identification of stem cells in embryonic and juvenile/adult (brain) tissue, detection and manipulation of cellular proliferation, preparation and culture of stem cells, implantation of stem cells into brain tissues, detection of functional integration. Both candidates will be involved in distinct projects focused on in vitro and in vivo ischemia models, respectively. The Neuropharmacological Unit of FAN, a non-profit research institution located in Magdeburg, has a proven reputation in the fields of synaptic plasticity and pre-clinical ischemia/stroke research. Our laboratories are located at the Center of Innovative Neurosciences and Neurotechnology opened 1998. We offer modern and well equipped lab space, creative collaborators and attractive fellowships at one of Germany TMs finest places for doing Neuroscience. Modern technologies are available at the FAN and at the Leibniz Institute for Neurobiology (IfN, our nearby located academic partner. Both positions are limited for two years. Since the fellowships are financed by the European Community, only inhabitants of European and associated countries can apply. FAN is an Equal Opportunities Employer. Please, send your application to Prof
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'New Oral Nanomedicines: Transporting Therapeutic Macromolecules across the Intestinal Barrier' (TRANS-INT).

assistant: **Innovation**

Despite the increasing number of macromolecules with potential impact in the treatment of devastating systemic diseases, these therapies have failed to deliver on their expectations because they cannot be administered in the fashion which is most cost efficient and has the highest patient compliance: the oral route. The availability of an oral form of administration could lead to a great improvement of classical therapies and it would also make a high number of new therapies feasible. To make this happen, the final objective of Trans-INT is to design nanocarriers specifically adapted to deal with the gastrointestinal ecosystem and use them for the development of new oral nanomedicines for diseases with high socioeconomic impact (i.e. metabolic diseases, pain medication).The concept behind TRANS-INT is the rational design of oral nanomedicines based on safety, mechanistic, bioengineering (multifunctional nanocarriers: high payload, drug protection, efficient drug transport, controlled release) and pharmaceutical technology criteria (scalable technology and stability).  The project will start with nanocarrier platforms on which the partners have IPR and freedom to operate: nanocapsules, nanoparticles, micelles made of combinations of lipids, polypeptides and polysaccharides, continue with the optimization and redefinition of selected nanocarriers. It is expected to end with (i) at least one oral nanocarrier prototype with a comprehensive GLP-tox package, which could be applied for the delivery of a high number of peptide molecules, (ii) at least one nanomedicine fulfilling target product profile criteria, with a comprehensive preclinical evaluation package, (iii) substantial integrative knowledge on the feasibility and potential of oral nanocarriers and nanopharmaceutical
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'SPAce-CompatiblE- Filters_in_dIelectric waveguide Technology' to be submitted under Horizon 2020.

assistant: **Abstract**

Satellite telecommunication systems are in continuous evolution, offering various types of interactive services. In order to provide such services ina cost effective manner, innovative and miniaturized technologies (low weight and volume) are required, allowing for increasing the density of thesatellite payloads, offering new services and thus reducing the cost of the satellite missions.SATFIT project aims to investigate the possible introduction into the space market of miniaturized and low-mass RF filters and multiplexers in L/Sbands based ondielectric waveguide resonatorsusing an innovative solution for thermal compensation that will make the filters space compatible.The SATFIT technology will lead to a drastic reduction of the resonator dimensions and weight (up to 50%) while maintain good performancewithrespect to existing technology (heavy waveguide and combline/coaxialfilters).The proposed devices will replace these filters in satellitetransponders operating in L/S band. Preliminary market survey identified TTC&M (Telemetry Tracking Command & Monitoring)as first applicationand MSS(Mobile Satellite Services) and Navigation systems (Galileo, GPS) as future ones. The market segment that can be taken, replacingstandard components is potentially 20% of the total market of L/S band filters for space.According to the preliminary business plan, the entering into the space market of SATFIT products would increase the companyturnover of morethan 30%. Phase 1 of the project is devoted to the study of the technical feasibility, analysis of the critical technical issues and risks, potentialmarket survey (including the estimation of market share) and the analysis of the technical and economical requirements.Also a business andstrategic plan for next project phases will be perf
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Development of an in vitro model for the human blood-brain barrier'.

assistant: **Concept**

The blood-brain barrier (BBB), separating brain from blood (as well as the bloodretinal barrier (BRB) between retina and blood) strictly controls the brain microenvironment, necessary for complex neuronal signalling. To assess the potential neurotoxicity or cerebral bioavailability of new drugs in development, academic groups and pharmaceutical companies would benefit from an in vitro model of human BBB, based on human brain endothelial cells in culture. Today, only preliminary models have been described, derived from primary cultures of non-human brain endothelial cells or from peripheral endothelial cell lines. The purpose of the present proposal is therefore to determine the extent to which immortalised human brain endothelial cell lines can be used for the development of an in vitro model of human BBB. (Since BRB characteristics are very close to those of BBB, this would constitute also an in vitro model of human BRB). This standardised model will constitute a valuable alternative to the current use of large numbers of animals in drug screening, will significantly accelerate the CNS-oriented drug discovery and development processes, and will ultimately decrease R&D costs in pharmaceutical industry.  Five contractors (two SMEs and three academic groups) constitute the proposing consortium. Two of the academic groups have top expertise in the biology of the BBB and have previously developed immortalised rat brain endothelial cell lines, the third is a world leader in the field of cell-cell endothelial junctions and vascular endothelial physiology. The two industrial collaborators are unique in Europe among Biotech companies in their specific expertise respectively in the establishment and genetic engineering of brain endothelial cell lines and in the CNS drug discover
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'A systematic approach towards the understanding, diagnosis and treatment of cdgs, a novel group of inborn metabolic disorders caused by defects of glycosylation', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

EUROGLYCAN will focus on a novel group of rare metabolic diseases caused by defects in protein glycosylation. The defects result in mental retardation, severe disease and physical handicap. Our major aims are to :1) develop effective tools and promote early diagnosis;2) collate patient information, useful for the identification and classification of novel types;3) raise awareness, because the disorders are largely unrecognised;4) establish a patient group large enough for systematic investigations and clinical trials.To fulfil these aims,1) a database will be created, maintained by the reference centre and accessible through Internet;2) the material will be reviewed and a depository of cell lines will be generated;3) diagnostic services will be made widely available;4) interesting cases will be selected for research;5) (mouse)models will be developed;6) collaborations will be sought with companies for the development of therapies.The project aimed at streamlining the diagnostic approach towards CDG. The number of diagnosed patients has increased thanks to the fact that the network has been offering free, expert diagnostic work-up of the clinical cases. At the end of the project, more than 400 cases have been compiled. EUROGLYCAN has certainly achieved to bring together the leading European groups with an interest and expertise in CDG and related syndromes. The close collaboration of several clinical and fundamental research groups has been key to the success. The activities were structured around a database, maintained at the reference centre. The main and the satellite clinical centres were involved in the recruitment of samples. The most interesting cases were forwarded to the research laboratories from the network.In addition, EUROGLYCAN has created new national refe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'VIrtualized hybrid satellite-TerrestriAl systems for resilient and fLexible future networks' in the context of a Horizon 2020 call.

assistant: **Objectives**

VITAL is an ambitious proposal addressing the combination of Terrestrial and Satellite networks by pursuing two key innovation areas, by bringing Network Functions Virtualization (NFV) into the satellite domain and by enabling Software-Defined-Networking (SDN)-based, federated resources management in hybrid SatCom-terrestrial networks. Enabling NFV into SatCom domain will provide operators with appropriate tools and interfaces in order to establish end-to-end fully operable virtualised satellite networks to be offered to third-party operators/service providers. Enabling SDN-based, federated resource management paves way for a unified control plane that would allow operators to efficiently manage and optimise the operation of the hybrid network. While innovations pursued by VITAL are transversal, the project will primarily focus on three key application scenarios: Satellite Virtual Network Operator (SVNO) services, Satellite backhauling and hybrid telecom service delivery.The solutions developed in VITAL will bring, through flexible integration of satellite and terrestrial segments, improved coverage, optimised communication resources use and better network resilience, along with improved innovation capacity and business agility for deploying communications services over combined networks. VITAL will address the development of a hybrid architectural framework, the required mechanisms to enable virtualization of SatCom network components, including performance optimisation and implementation of a number of virtualised functions, and the design of an SDN-enabled, federated resources management framework, embedding strategies and algorithmic solutions to provide end-to-end communication services. Proof of Concept validation of VITAL solutions and enabling technologies throu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Autonomous Production of Images based on Distributed Sensing'.

assistant: **Objectives**

Democratic and personalized production of multimedia content is one of the most exciting challenges that content providers will have to face in the near future.  In this proposal, we plan to address this challenge by proposing a framework to automate the collection and distribution of digital content. As a federating objective, APIDIS targets cost-effective autonomous production, so as to make the creation of audiovisual reports profitable, even in case of small- or medium-size audience. First, APIDIS will investigate the automatic extraction of intelligent content from networks of multi-modal sensors. Intelligence refers here to the identification of salient segments within the audiovisual content, using distributed scene analysis algorithms. Second, our project will exploit that knowledge to automate the production of video content for controlled scenarios, e.g. most notably sports events or surveillance. Finally, the APIDIS consortium will consider personalized and potentially interactive content summarization mechanisms, to address heterogeneous user needs and access conditions. The potential applications of the integrated technology and methodologies that will be developed within APIDIS are numerous, ranging from personalized access to digital media related to local sport events through a web portal or a mobile hand-set; cost-effective and fully automated production of content dedicated to small-audience, e.g. souvenirs DVD, university lectures, etc; but also automated summarization for video surveillance.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Towards sustainable modes of urban and peri-urban food provisioning' in the context of a Seventh Framework call.

assistant: **Objectives**

Short food supply chains have been advocated as a means of rural development, as they improve the position of primary producers in the value chain. In this proposal we look at short supply chains from the perspective of urban rather than rural development. Short supply chains can play a role in addressing urban problems such as climate change, obesity, storm water control, etc.Short food supply chains have been advocated as a means to reduce CO2 impact of the agricultural system. Although a reduction of food miles certainly contributes to reducing climate impact, this proposal takes as premise that to really improve the ecological performance of the food system other flows of goods and services need to be shortened as well (e.g. nutrient, water, and carbon cycles need to be closed). In the current context these aspects are usually treated separately, this proposal argues to treat them more integrated.The research will analyse the way in which several European city regions deal with short supply chains in food, nutrients, water, and carbon. The project will facilitate selected SMEs to further innovate in food production and delivery, nutrient and water management, and multifunctional use of space, and will disseminate the results among a wider audience of SMEs. By doing so, the research will look beyond the state of the art, it will suggest how city regions could look like if they chose to further relocalise their food system.Finally the project will also establish links with stakeholders and RTD activities regarding urban and peri-urban agriculture and short chain delivery of food in urban and peri-urban areas in developing countries. This will be organised through a process of dialogue, sharing of experiences, exchanging of best practices and joint learning.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'International Cooperation activities in future and emerging ICTs' (INTERLINK) under Sixth Framework.

assistant: **Objectives**

The goal of InterLink is to support coordination actions that will enable the European research community to interact with research communities outside Europe in a series of strategic, basic research areas, related to Information Society Technologies (IST). Thematic areas have been carefully selected based on the need to address the evolution of the Information Society in the next 10-15 years and include (1) software intensive systems and new computing paradigms, (2) ambient computing and communication environments and (3) intelligent and cognitive systems. These areas are closely related to a number of strategic research areas as well as to a number of ongoing proactive initiatives funded by FET in FP6.The main aims of InterLink are:1. To identify and address world-scale, basic research problems where significant added value is expected to be gained from world-wide cooperation.2. To establish communication and cooperation mechanisms within and beyond Europe in order to support the formation and functioning of related scientific communities.3. To identify complementarities in the selected areas among EU countries and other involved countries that can give rise to knowledge and technology exchange.4. To define joint research agendas, in terms of research priorities, road-mapping activities and joint RTD initiatives.The project is based on three Working Groups that will consist of international teams of researchers with proven expertise in their fields. Advanced communication tools will be provided aiming at a global networking of research communities. Several workshops will be organized to foster the RTD dialogue, promote the interactions within each Thematic Area and build technology roadmaps at an international scale. The ambitious goals of InterLink will be promoted t