RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Elite Politics in Electoral Autocracies'.

assistant: **Objectives**

Today most dictators exploit democratic institutions such as multiparty elections or legislatures to cover their autocratic rule. To carry out this form of rule, dictators need a loyal coalition of politicians to gather supporters, advance policies and win elections. While this loyalty is central to regime survival, elite divisions within authoritarian governments can induce political change. Yet, what type of divisions matter and whether such change will be democratizing are unclear. Defectors might have the resources to embolden pro-democracy groups, but they may also face repression, worsening democratization prospects. What type of divisions within the ruling elite can weaken modern autocracies? What are the mechanisms that underpin the relationship between defections and democratization?ELITE offers a new theoretical framework, innovative data, and empirical research to identify and explain the strains and disruptions within authoritarian governments that induce democratization. It develops a theory of the elite origins of regime (in)stability, focusing on divisions within the ruling elite. ELITE builds a novel dataset on political elites’ resources and dissent strategies in 28 prominent electoral autocracies—today's most common form of autocracy. Cutting-edge mixed methods test why and how elite divisions strengthen anti-regime groups and weaken leaders' tools to stay in power. Findings will inform academic and policy debates on the processes that weaken modern dictatorships. Dr. Adrián del Río Rodríguez has broad expertise on the topic of elite politics in autocracies and methodological skills to carry out the ELITE project. The Department of Political Science, University of Oslo, will host Dr. del Río, and Prof. Carl H. Knutsen–a top international scholar in aut
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Early stage CARdio Vascular Disease Detection with Integrated Silicon Photonics', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Early identification of individuals at risk for CVD allows early intervention to halt or reverse the pathological process. This is the driver of Medtronic and partners to develop a mobile, low-cost, non-invasive, point-of-care screening device for CVD.Assessment of arterial stiffness by measurement of the aortic pulse wave velocity (aPWV) is included in the latest ESC/ESH guidelines for CVD risk prediction. Besides aPWV, early identification of arterial stenosis and cardiac contraction abnormalities can be used to improve CVD risk classification. However, no tools are available today to screen a large population at primary care on these parameters, and individuals that are considered to be at low or moderate risk are too often undiagnosed.The objective of CARDIS is to investigate and demonstrate the concept of a mobile, low-cost device based on a silicon photonics integrated laser Doppler vibrometer and validate the concept for the screening of arterial stiffness, detection of stenosis and heart failure. We will:•Investigate, design and fabricate the optical subsystems and components: silicon photonics chip with integrated Ge-detectors, micro-optics, micro-optical laser bench, optical package•Integrate the subsystems and build a multi-array laser interferometer system•Develop a process flow scalable to high volumes for all sub-systems and their integration steps•Investigate and develop the biomechanical model to translate optical signals related to skin-level vibrations into underlying CVD physiological events•Validate the system in a clinical settingPhotonics integration is needed to enable a device that is mobile (small size, small weight, robust (no moving parts), low cost (high volume scalable process flow) and allows fast screening (laser array).The partners commit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Transposon based Forward Genetic Screen for the Identification of ncRNAs involved in Colorectal Cancer Metastasis'.

assistant: **Concept**

In the era of target-based cancer therapies there is still missing a univocal hit for treating cancer metastatic spread, which is ultimately the main cause of cancer death. Non-protein-coding RNA transcripts (ncRNAs) were for long regarded as transcriptional noise; interestingly, it turns out that most of the genome does not carry protein-coding genes (PCGs) and yet is transcribed in a developmentally regulated manner producing ncRNAs with biologically relevant functions (e.g. development and tumor). As for tumor initiation, also for tumor metastasis, it is now becoming common knowledge that the set of metastasis promoting and suppressing genes consists both of PCGs and ncRNAs. Notwithstanding the growing interest in ncRNAs, the ability of forward genetic screens to discover novel genes has not been used in the ncRNA field. Therefore, with the present project we will develop a novel forward genetic screen that specifically retrieves ncRNAs. We will use this genetic screen in human intestinal epithelial cells, which will be tested in anoikis (death induced by anchorage absence) resistance assay. Cells that survive anoikis, which is a rate limiting step during cancer cell metastasis, will have loss of function mutations in ncRNA genes that we will then proceed to characterize.The present proposal is relevant for the 2011 People Work Programme since it will support the applicant Milena Sabrina Nicoloso in establishing an independent research position in Europe (as a group leader) and ultimately it will improve EU, Italy and the Host Institute excellence thanks to the knowledge and expertise that the applicant acquired during a 5 year international experience in EU competitor countries.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'A New proTection devIce for FOD' under Horizon 2020.

assistant: **Concept**

The main objective of this innovation action is to develop a Foreign Object Debris (FOD) protection device applied to an electrical ECS fresh air inlet, validated to TRL5. This will be achieved through the following two-stage design process, each with their own secondary objectives:1. Preliminary design, which aims to: a. capture the top level requirements through a survey of the user needs and used to develop a set of baseline candidate concepts. b. use innovative design methods to conduct a concept study. c. verify prototypes rapidly using a combination of CFD and additive manufacturing, as measured by comparing calculated separation efficiency and pressure loss. d. refine the highly ranked concepts via a trade-off study and determine the best suited solution that meets all the top-level requirements, measured through a scoring system. e. produce a preliminary design from the winning concept, including feasibility study, sensitivity analysis, risk assessment, and system requirements report, measured through a preliminary design review (PDR) which demonstrates compliance with the user needs.2. Detailed design, which aims to: a. define an aerodynamic geometry for the intake protection and FOD separation device which demonstrably meets the relevant requirements and integrates with the mechanical interfaces of the existing intake scoop inlet, scoop ducting and eECS inlets, and is measured through Wall-Modelled LES simulations. b. produce a detailed design and subsequent manufacture of the full-scale intake protection and FOD separation device. c. design a test bench to validate the intake protection and FOD separation device. d. deliver a final full-scale working prototype to the Topic Leader which demonstrably meets the user needs, as measure.


**Keywords:** Intake prot
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'A novel wearable medical device and eHealth system to improve the mobility of patients with hemiparesis' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

REMOD is a young German SME with 6 employees, specialized in rehabilitation technology and rehabilitative medicine. We deliver innovativ training for chronically ill patients, and develop rehabilitation devices linked to the training content. One in five people experience a stroke at some point in their lives, and half of all strokes lead to paralysis of one side of the body, called hemiparesis. There are around 550,000 hemiparesis cases per year in the EU. Strokes cost the EU about €34.3 billion per year, of which €17 billion is spent on the treatment of hemiparesis. These costs do not include indirect costs due to incapacity to work, or unpaid care provided by relatives and friends. As such, strokes and hemiparesis are of great socioeconomic importance. Since there is no known cure for hemiparesis, treatment focuses on rehabilitation to minimise further loss of body function and reduce pain, muscle regression, or spastic paralysis due to reduced mobility. Existing rehabilitation methods includes: weak dorsiflexion, orthosis, hippotherapy and the use of therapeutic and neurorehabilitation devices. Such rehabilitation accounts for €8 billion per year of direct costs in the EU. Mobility improvements can be made with intense physiotherapy, but these improvements are not lasting due to brain damage which affects movement memory. Currently no solution exists that leads to a lasting improvement in the mobility of hemiparesis patients.We have developed, patented, and demonstrated (to TRL6) a novel wearable medical device which is embedded into a special vest to correct the posture and movement of patients suffering from hemiparesis and are now miniaturizing the device and developing the MovEAid eHealth system, containing the device and vest, for use by hemiparesis patients an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Entering the deep QuAntum Regimes of NOnequilibrium Thermodynamics' under Horizon Europe.

assistant: **Concept**

Can we extend nonequilibrium thermodynamics to probe complex quantum phenomena? In the 90s, the scope of thermodynamics broadened to include small systems and far-fromequilibrium transformations. Building on these advances, the emerging field of quantum thermodynamics has recently lead to breakthroughs formulating nonequilibrium thermodynamics in the quantum regime. Motivations range from the search of quantum advantages in heat engines or quantum batteries, to the expression of global constraints on many-body quantum dynamics stemming from the Second Law. However, deep quantum regimes where largest deviations from classical thermodynamics are expected remain elusive, limiting applications: At weak system-reservoir coupling, a finer description of the coherent-dissipative regime is lacking to evaluate the resource costs of quantum control, optimize quantum heat engines or understand the energy transfers during a quantum measurement. This in turn hinders experimental developments of quantum thermodynamics in more platforms. To express fundamental nonequilibrium bounds on the energy exchanges with quantum materials and use thermodynamics to probe many-body dynamics, new coarse-grained description are crucially needed.Project QARNOT will address those timely issues owing to a novel strategy combining cutting-edge methods from quantum open system theory beyond the most common approximations with newly-derived universal thermodynamic descriptions of quantum systems, to bridge the gap between quantum thermodynamic laws and experimentally or theoretically accessible physical variables.By unlocking the deep quantum regimes of nonequilibrium thermodynamics, QARNOT will provide a new versatile analytical toolbox to probe quantum many-body and dissipative dynamics. Notably, QARNOT
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Turning unexploited food waste into biomethane supplied through local filling stations network', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The overall objective of Bin2Grid concept is to promote segregated collection of food waste as energy source, conversion to biogas, and its upgrading to biomethane and utilization in associated network of filling stations.To that end, accent will be given to defining strategies for establishing efficient network of food and beverage waste collection methods and practices. Also, whole range of food waste producers will be taken under consideration, i.e. manufacturing entities, catering/food services, retail stores. Since biological treatment (anaerobic digestion) is without an alternative for energy utilization of food waste and together with other raw materials creates a synergy for renewable energy production (biogas/biomethane). One of the biggest advantages of such a concept of energy production is having two issues covered at the same time: environmental protection with sustainable management of food waste and the production of renewable energy with its utilization as a biofuel.The existing technologies which are specific for this kind of raw materials will be explored. Having in mind that chemical energy of biogas is fully used when it has been upgraded to biomethane and used as a biofuel, particular attention will be given to advanced biogas to biomethane upgrading techniques for purification and technical requirements for its usage through local filling stations as a biofuel, in public transportation sector in particular (e.g. waste management trucks).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Methods and tools for natural-language interfacing to standard software applications'.

assistant: **Objectives**

The primary objective of the project is to develop the technology and provide tools which will enable end users to interface, using natural-language, to computer applications systems, and to apply this technology successfully to obtain a pre-competitive product validated in selected end-user applications.The approach is both application and end user centred. Applications centred in that the project will start with the analysis of existing applications, studying how to provide them with Natural Language (NL) interfaces which would satisfy their users. End-user centred in identifying and analysing the interests and requirements of end-users and specifying design requirements on future applications interfaces to allow them to include powerful natural language capabilities.The project also has longer term, ambitious, but precise and feasible, objectives. It will place a number of strategic European IT companies in a leading position against foreign competitors, mainly large USA software products and services companies.One of the foundations of the project is that two important aspects should be recognised and implemented:- the integration of previous results from European Language Engineering projects- compliance to formal and 'industry' standards, related to both operating environments (POSIX, Windows) and application inter-operability (CORBA, COM).The design requirements specified will be consistent with and built upon emerging application interconnection standards, such as CORBA 2.0 or COM (OLE 2). These inter-operability standards may have to be extended to cover the requirements of a range of different applications and natural language interaction. A proposal will be produced to the appropriate bodies for extension to fully support MELISSA.The RTD work is focused on th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Photocatalysis to crop protection: asymmetric cascades for chiral heterocycles' (PHOTOCHIRO) under Horizon 2020.

assistant: **Objectives**

Food security and sustainable agriculture is a significant and current challenge to society in the face of growing global consumption. PHOTOCHIRO seeks to provide some solutions through assisting the development of more effective crop protection technology. Specifically, we aim at the synthesis of novel chiral amines, which are common motifs in biologically active molecules, by using light-driven organocatalytic cascade processes. Asymmetric organocatalysis and photochemistry, two powerful strategies of modern chemical research, have extraordinary potential for sustainably preparing the novel organic molecules required for driving innovation in the pharmaceutical and agrichemical industries. However, the control of enantioselectivity in photochemical processes poses a fundamental scientific challenge, and PHOTOCHIRO asks whether asymmetric organocatalytic photochemical cascades can be used as an effective tool for the rapid synthesis of novel chiral pyrrolidine and piperidine building blocks. The chiral molecules prepared in this project will be screened for herbicide, insecticide, and fungicide activity in a multidisciplinary collaboration with Syngenta. This fellowship brings a new collaboration to the host institution, transfers knowledge of advanced techniques in asymmetric catalysis and photochemistry to the candidate, and, in addition, knowledge of these new enantioselective photocatalytic synthetic techniques to the industrial partner. The results have the potential to increase the economic competitiveness of Europe through Knowledge and Technology Transfer and are in line with one of H2020 Societal Challenges to secure ""viable food production in face of a growing world food demand"". The multi-cultural and intersectoral nature of this project will broaden Dr Ho
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Injectable macroporous biomaterial based on Calcium Phosphate cement for bone regeneration', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

Osteoporosis and bone degeneration in aging populations as well as bone defects caused by trauma and pathology grounds a societal need for therapeutic products. The main goal and the breakthrough of this project are to implement a novel concept of biomat erials for bone regeneration, with a range of properties that elicit specific cell responses. The biomaterials developed in this project will give improvements in health, quality of life, environment and safety. These multifunctional biomaterials will be injectable, porous, intelligent and biodegradable to promote osteogenesis and angiogenesis. Because these biomaterials will be injectable, they will be applied by means of minimally invasive surgery. This means less suffering by the patient, reduction o f health care cost, simple surgical technique and improved working conditions. These biomaterials will be an advantageous alternative to autologous bone due to their large availability and that they can be obtained sterilized right off the shelf.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Diversity in Synthetic Biological Systems' (SynBiol-DynHet) targeting Horizon 2020.

assistant: **Abstract**

One key problem in the investigation of living systems is their complexity. Synthetic biologists can create artificially designed biological systems, whose design reduces the complexity, and can thus address simplified and specific questions. Theoretical investigations of these systems help to understand these questions, for example by evaluating whether a simple model already predicts the features shown in experiments.This proposal provides a step towards understanding living systems by theoretically studying diversity in microbial populations. The aim is to investigate both spatial diversity, such as barriers, as well as agents with different traits within a population. This will be done with the goal of answering important ecological as well as microbiological questions. In terms of the ecology, this work will address how spatial barriers, or the presence of diverse agents, can influence the formation of biodiversity and cooperation. In its engagement with microbiology, it will investigate a microbial population's reactions to randomly distributed antibiotic drugs, and the ability to tolerate these antibiotics. With the development of new experimental procedures that allow closer investigations of both these issues, an improvedtheoretical description is now required alongside such advances.I will investigate all questions in close collaboration with synthetic biology experiments. This project will allow  me to combine my background in the theory of condensed matter and chemistry to work on living systems research, before obtaining an independent researcher position in the field of biological physics.