RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Revolutionizing Sustainable Architecture with High-Efficiency Geopolymer Thermoelectric Modules for Energy Harvesting'.

assistant: **Objectives**

Thermoelectric (TE) technology, which can convert thermal energy into electrical power, represents a crucial clean energy innovation. When integrated into the field of architecture, it holds the potential to transform buildings from passive energy consumers into active energy generators. Furthermore, it can serve as an effective strategy to mitigate the rising urban heat island effect and soaring summer temperatures, which are increasingly prevalent in the European Union (EU). In recent years, TE cement composites have garnered significant attention due to their robustness and cost-effectiveness compared to commercial TE modules. However, the thermoelectric performance of TE cement composites typically falls significantly below the requirements for practical applications. This project aims to lead the development of high-efficiency geopolymer TE modules for energy harvesting, thereby advancing the EU's progress towards achieving nearly zero-energy buildings. The proposed high-efficiency geopolymer TE module represents an innovative building material that can fulfill both structural (mechanical) and TE (energy harvesting) roles. The mechanical and thermoelectric properties of these geopolymer modules will be enhanced through the addition of various additives. Subsequently, the project will analyze the reversibility/cyclability aging and mechanical durability of geopolymer TE modules to further enhance their functionality and applicability. Additionally, a comprehensive thermo-electro-chemo numerical model will be employed and validated using data obtained from microstructural assessments of aging geopolymer TE modules.


**Keywords:** Geopolymer; ThermoelectricEnergy harvesting;  Resilience
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Development of Space Astrophysics in Crete' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Space Astrophysics is a research domain  which has benefited greatly from the recent advances in technology and has contributed to the most fundamental discoveries in various areas of Astrophysics over the past 20 years. The nature of operation of space observatories (all experiments are designed remotely and data is archived in servers accessed via the web) make it possible for researchers in regions in the outskirts of Europe with no access to other major research facilities to perform high quality science. Over the past three years the Astrophysics Group in the island of Crete (Greece) has invested a considerable fraction of its human resources in Space Astrophysics by hiring three new tenure track faculty with expertize in X-ray and Infrared Space Astrophysics.  We propose to use the opportunities provided by the Capacities Program to further develop the research potential of our group. Our project will be based on twinnings with top Space Research Institutes in Europe (CEA/Saclay, France and MPE/Garching, Germany), on hires of experienced researchers, on upgrading our telescope equipment, and on workshop/conference organization. Our goal is to train our local personnel and improve the visibility of the group so that at the end of the proposed program the group will be at a level which will enable it to collaborate with major european research centers on forefront research projects.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Analysing the heavy element factories of the Universe : photometric and spectroscopic sample study of kilonovae' (GW), addressing dissemination and exploitation.

assistant: **Impact**

The recent first detection of gravitational waves from a binary neutron star merger and its associated optical counterpart, the so-called 'kilonova', opened up a new era of multi messenger astronomy. The intense photometric and spectroscopic campaign that followed provided tantalising evidence that kilonovae are a prime source of heavy elements in the Universe. Nevertheless, with just a single event, and with only rudimentary theoretical models, it remains unclear how important kilonovae are in enriching the cosmos. This project aims to address this issue by building the first sample of kilonovae through dedicated follow-up observations of future compact binary mergers detected with the LIGO/Virgo gravitational wave detectors, which will soon come back online. The three principle objectives will be to (i) determine the ejecta mass distribution of kilonovae, (ii) identify the composition of kilonova ejecta and (iii) understand the progenitor systems of kilonovae from their host galaxies. Working with Jesper Sollerman and his GREAT group at Oskar Klein Centre, I will have access to ENGRAVE and GROWTH, which are two leading projects set up with the explicit goal to follow-up and monitor gravitational wave electromagnetic counterparts. The group at Oskar Klein Centre is leading vital research in theoretical modelling of compact object mergers. Combining observational resources, theoretical models and my analytical expertise in transient astronomy, this project promises to greatly contribute to the investigation of gravitational wave sources, kilonovae and the nucleosynthesis of heavy elements.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Visualizing aquifers: sustainable water use  in the Atacama Desert and beyond'.

assistant: **Innovation**

Billions of people rely for their everyday existence on aquifers. The invisibility of these waters, however, poses formidable challenges for those who rely on them: locating, measuring and controlling aquifers is complex and precarious, yet of utmost importance for human survival in many parts of the world. The overall aim of the proposed project is to explore the vital connections between humans and aquifers in everyday life. Building on trans-disciplinary studies that consider water as the contested nexus of social and political affairs, this project explores groundwater as both mediating and generating diverse ‘groundwater practices’: as an invisible resource, groundwater requires visualization; as an underground supply, it calls for innovative extractive techniques; as a finite good, groundwater needs to be regulated and controlled; and as a practical everyday resource, it sustains irrigation, sanitation, and human consumption. Through ethnographic fieldwork in Atacama Desert of Northern Chile, this project will develop an analytical framework to understand how social relations are affected by various groundwater practices. The proposed research will explore such practices with a focus on the effects that the visualization of aquifers has on socio-economic and eco-political inequalities. Through transdisciplinary training at the Universidad Católica del Norte, I will strengthen methodological skills to study the groundwater practices of indigenous communities, hydro-geologists and state administrators. I will transfer the acquired skills to the UNESCO-IHE Institute for Water Education, where I will strengthen understandings of the dynamics among groundwater practices, power, and culture, providing trans-disciplinary input for policymakers engaged in the design and r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Pulmonary Imaging Network'.

assistant: **Concept**

The lung is probably one of the most difficult organs to study by MRI because of its low proton density. Still, MRI is very interesting as not exposure of ionizing radiation to patients and its important role for translatability studies. Moreover, assessment of regional pulmonary perfusion and ventilation with clinical value as an indicator of lung function by MRI has been demonstrated using MRI based techniques both with hyperpolarized and fluorinated gases, oxygen and contrast agent free methods. The π-net ITN will undertake successful efforts (funded under the fifth and six framework program) and previous bilateral collaborative and complementary work of different European research teams to contribute to the field of lung functional MRI. π-net proposes very complementary and strongly interlinked research and training activities for these functional studies. The main research activity line aims at applying MRI based techniques for diagnosis (human and preclinical activities) and treatment (only preclinical) monitoring of lung diseases (COPD, lung cancer, cystic fibrosis, asthma), without excluding the possibilities that other imaging techniques (nuclear, CT and optical imaging) and molecular approaches (including molecular imaging and metabolomic analysis) may bring to the field. Π-net plans a training program to provide new ESR high level multidisciplinary scientific education and complementary skills for animal studies, MRI and other imaging techniques, and on translational aspects of research.The network is formed by 9 groups, located in 5 different countries (Spain, France, UK, Germany and Sweden). The centres hold researchers with previous experience in the network work and with researchers with high quality scientific production rate, and with experience in MRI
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Next-Generation Drug Discovery Platform for Targeting Cancer Stem Cell Pathways' (ACHILLEUS).

assistant: **Innovation**

Colorectal cancer (CRC) is one of the most frequent cancers with a high burden on society. In Europe alone, more than 340,000 people are diagnosed with colorectal cancer each year. While treatment options of CRC have expanded over the last decades, the survival rates of patients suffering from advanced-stage cancers remain poor. Stemness of neoplastic cells has been proposed as a major factor in treatment resistance and high relapse rates, however, drugs targeting stem cell signaling pathways in cancer are still lacking today. We propose developing and validating a new drug discovery platform based on patient-derived organoids (PDOs) and machine learning-assisted phenotypic target validation and drug discovery. Using this platform, we have previously shown that we can identify a broad spectrum of phenotypes beyond lethality, including drug-induced changes in stemness of PDOs. As part of the EIC Open Transition project, we will validate our next-generation platform for identifying therapeutics to target stem cell signaling pathways in CRC. Based on results by us showing that an interaction of MEK and Wnt signaling shifts the balance between stemness and differentiated cells, we will target Wnt pathways as a demonstrator for the technology. The ACHILLEUS project targets critical vulnerabilities in cancer and is based on technologies and approaches developed during previous ERC Advanced and ERC Proof-of-Concept grant-funded projects. The project?s ultimate aim is to spin out a NewCo as a phenotypic drug discovery platform for targeting cancer stem cell pathways.


**Keywords:** Drug discovery, phenotypic drug discovery, machine learning and computer vision, stem cell signaling, Wnt signaling, high-throughput biology
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Assistive Medical Robotics for Very Early Mobilization of Critical Care Patients' (VEMOtion) targeting Horizon Europe.

assistant: **Abstract**

Early mobilisation in the ICU is a highly effective tool in patient rehabilitation, clinically proven and acknowledged by major international medical bodies. Despite the clear financial advantages for healthcare systems and health benefits for patients, it is currently performed with only 25% of ICU patients due to lack of resources and hazardous nature of the manual procedure. Reactive Robotics has developed VEMOTION, the world’s first AI-driven robotic assistance system for early mobilisation in ICUs. VEMOTION enables the clinically proven benefits of early mobilisation to be delivered safely to all ICU patients, accelerating recovery by 20%, reducing treatment costs, increasing ICU capacity by 27%, and improving patient outcomes. Introduction creates a >€5bn market for ICU robotics.The EIC project (€2.5M grant, €15M equity) delivers crucial product development and large-scale clinical trials to validate the clinical/business case and accelerate scale-up.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Effects of fluxes in string compactifications'.

assistant: **Concept**

The research topic of this proposal is String Theory compactifications and the emergence of Einstein gravity and the Standard Model in the low-energy limit. The specific aspect we will address is the possibility to ton on non-zero fluxes on the compact manifold. Fluxes have the following interesting and not fully explored features: they fix some of the continuous parameters of the vacuum (module), they can induce super symmetry breaking, and they allow for a non-trivial warp factor which may account for the hierarchy between the Planck and the electro weak scales. The research objectives are:(i) find general conditions for the existence of supersyrnmetric solutions with given fluxes,(ii) study the resulting potential for the module,(iii) derive the effective theory on intersecting D-brines carrying the Standard Model fields, in a flux background, and(iv) study implications for super symmetry breaking and the vacuum stability. The theoretical tools employed are those of quantum field theory, general relativity, and certain branches of modern mathematics. Specifically methods from gauged super gravity, boundary conformal field theory and D- brines, string dualities and the Ads/CFT correspondence, and the recently developed techniques of matrix models will be used. The young researcher will benefit from the presence of experts on these topics in the host laboratory. The proposed research can create synergies among different branches of physics and of mathematics, and could be relevant to the future experimental activities in particle physics (especially at the European Large Hadrons Collier in CERN) and in cosmology.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Bridging the Evolution and Epidemiology of HIV in Europe' (BEEHIVE).

assistant: **Innovation**

The aim of the BEEHIVE project is to generate novel insight into HIV biology, evolution and epidemiology, leveraging next-generation high-throughput sequencing and bioinformatics to produce and analyse whole-genomes of viruses from approximately 3,000 European HIV-1 infected patients. These patients have known dates of infection spread over the last 25 years, good clinical follow up, and a wide range of clinical prognostic indicators and outcomes. The primary objective is to discover the viral genetic determinants of severity of infection and set-point viral load. This primary objective is high-risk & blue-skies: there is ample indirect evidence of polymorphisms that alter virulence, but they have never been identified, and it is not known how easy they are to discover. However, the project is also high-reward: it could lead to a substantial shift in the understanding of HIV disease.Technologically, the BEEHIVE project will deliver new approaches for undertaking whole genome association studies on RNA viruses, including delivering an innovative high-throughput bioinformatics pipeline for handling genetically diverse viral quasi-species data (with viral diversity both within and between infected patients).The project also includes secondary and tertiary objectives that address critical open questions in HIV epidemiology and evolution. The secondary objective is to use viral genetic sequences allied to mathematical epidemic models to better understand the resurgent European epidemic amongst high-risk groups, especially men who have sex with men. The aim will not just be to establish who is at risk of infection, which is known from conventional epidemiological approaches, but also to characterise the risk factors for onwards transmission of the virus. Tertiary objectives i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Optimal tooling system design for large composite parts' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The general objective of the project is to smartly handle the overall process of the composite integrated parts production reducing costs in two ways. First, by adequately simulating the spring back produced after the curing process and providing solutions in order to reduce the costs of reworking or assembly. Secondly, by simulating the thermal model of the set tooling/compositepart/vacuum bag and auxiliary parts under autoclave conditions to optimize the cure cycle temperatures distribution creating more uniformity in the composite part, lower residual stress, lower energy costs and better environmental friendliness. Given the large number of parts produced and their growth, the importance of the target is large.For that general purpose, the first specific objective of the OPTOCOM project is to carry out all the necessary steps to design and manufacture large tool for a composite complex structural part, typically a double curvature fuselage stiffened panel with co-cured stiffeners of about 2x1sqm. The stiffening elements shall be of both “Z” type and “Ω” type cross section. Requirements such as high accuracy and rigidity, typical autoclave conditions, CTE matching, durability, minimal weight, provisions for transport, handling and accessories integration for easy demoulding, shall be imposedSecond, is to develop analytical and FEM models which adequately simulate the distortions and spring back occurring in the curing process. This requires to establish the correct hypothesis and to obtain real material performance behavior both along the curing process and when the composite is cured, in order to be introduced into the model.Third, is to set up FEM simulation models to assess the thermal behavior and temperature evolution of the set of elements that get in the autoc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Process visualisation and analysis Endoscope System' (PROVAEN).

assistant: **Concept**

Advanced materials offer huge potential for Europe in terms of enabling the development of new added-value products. However, a significant barrier to realising that potential is the lack of suitable processing technologies necessary for their economic large-scale manufacture. Specifically, there is an increasing requirement for versatile in-situ process equipment that can be used for real-time monitoring of the particulate flow systems, which are essential in the manufacture of many advanced materials and pharmaceuticals. However, these fluid flows are frequently found in hostile and inaccessible environments. Existing analytical techniques such as high- resolution microscopy and flow velocity mapping require large, expensive, complex and delicate laboratory instruments that cannot be used in these conditions.PROVAEN will develop a radical solution to this problem, capable of operating in harsh and inaccessible environments, thus enabling effective product development, precise optimisation of material proper ties and process control and fault diagnosis. This will be achieved through the development of component technologies to enable the application of advanced laser-based particle analysis techniques via endoscopic probes, interfacing with a simple-to-use, portable system, enabling routine and fast application inside actual process equipment. The fluid flows we will address consist of liquid or gas phase (or both), and the particles within them may exist as solids, liquids or gases.The performance of the final product is often critically dependent on the physical properties of the particle as well as the chemical composition, and both the physical and chemical properties are critically influenced by the nature of the particle flow patterns within the process. PROVAEN