RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'RNA particles for Preparedness against Infectious Diseases'.

assistant: **Objectives**

BunyaVax builds unprecedented technology for cost-effective and rapid development of vaccinesagainst newly emerging viruses. The platform can be a valuable tool in quickly controlling the spread of new virus strainsamong populations. The timing of RAPID closely corresponds with a current focus of the vaccine industry on novel vaccineplatform technologies that enable rapid response to emerging threats.The BunyaVax RNA particle technology combines the efficacy of live vaccines with the safety of inactivated or subunitvaccines – which are currently the standard vaccine technologies. A unique characteristic of the RNA platform is that itallows for ‘plug and play’ application. Any gene can be plugged into the RNA particle genome to generate inherently safeand efficacious vaccines. The platform can stably express a broad variety of pathogen derived antigens. A major advantageis that development and manufacturing can be completed in a timeframe of 16 weeks which is at least twice as fast ascurrent methods. The BunyaVax technology is in a stage of proven efficacy in sheep.RAPID is designed to prepare for partnerships with vaccine manufacturers and/or venture capital firms and to lay thefoundation for clinical application of the vaccine platform. Key steps for upscaled production levels will be taken. The innovation project is at the core of the strategy of BunyaVax. The project is instrumental for reaching a stage in which commercial partnerships can be explored. Ultimately, this will allow BunyaVax to forward the technology to a stage in which industry can use it to develop vaccines for controlling veterinary and human infectious disease outbreaks at an earlier stage than currently possible.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Transmission of Electromagnetic Waves through Sea Water for Imaging Parameter Measuring and Communications'.

assistant: **Objectives**

This project concerns the propagation of electromagnetic (EM) waves through sea water (clear, murky and polluted) for frequencies in the range lOMHz to 30GHz. The propagation characteristics depend upon a combination of the conductivity (permutation) and dielectric (epsilon) properties of the various conditions of sea water. Theoretically the spatial and temporal variations of the electric (E) and magnetic (H) fields are obtained from Maxwell's equations with the dielectric properties being given by Debye's equations. Experimentally these solutions can be examined in the laboratory using metal resonance cavities filled with simulated sea water with various quantities of included sand. Initially measurements of the attenuation coefficient (alpha) and the velocity (v) of the E (or H) field waves may be obtained from which permutation and epsilon(=epsilonI+jepsilonII) will be obtained as a function of frequency. If the cavity is unlined then usually the conductivity dominates in this frequency range, however, if the cavity is lined, with an insulator, then the dielectric term dominates. Precision measurements may be obtained by using state of the art' spectrum analysers and data logging systems. Measurements obtained using these techniques will allow accurate measurements of both permutation and epsilon to be obtained for comparison with a relaxation theory. The cavity technique can also be readily used in either a dock or coastal water environment. Hence the variations of permutation and epsilon with frequency may be compared for conditions of clear, murky and polluted sea water. The results of this investigation will be aimed at two important offshore applications. The first application is as a pollution monitor. The cavity technique will allow permutation, epsilonI and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Turning BacTERia into factories of BIOdegradable PLASTICS' to be submitted under Horizon 2020.

assistant: **Abstract**

Plastics are littering our environment, contributing to health problems and it is urgent to find sustainable alternatives. Polyhydroxyalkanoates (PHAs) are natural (not synthetic) and non-toxic polyesters and can be derived from bacterial fermentation. However, the amount produced is low for the demand, costs for production are high and non-competitive when compared to plastics from crude oil. Therefore, it is urgent to overcome this limiting factor by increasing the production of biodegradable bioplastics. This proposal is promising and can impact our everyday life through innovative ways to increase production and versatility of bio-based degradable plastics. Herein, I propose to improve the production of different kinds of PHAs through two chassis: Sinorhizobium meliloti, and Pseudomonas putida, both recognized as safe (GRAS status) and able to grow in fermenters. First, I aim to use the gained knowledge during my PhD training in small RNA regulators (sRNAs) in S. meliloti, as well as the expertise of my host group in RNA-mediated regulation of gene expression and RNases, to improve the production of one kind of PHA in the first chassis. Second, I will implement transcriptome analysis of P. putida and generate synthetic sRNAs as an innovative vector for the control of key enzymes involved in PHA production in the second chassis. Finally, pilot fermentations and metabolic modulation strategies will upscale and upgrade the bioplastics accumulated in both organisms (collaborating with world experts in bioplastics: short-stay and secondment) and connect us to the non-academic sector. This multidisciplinary project will be broadly advertised to different audiences. I will acquire new knowledge, transferrable skills, training and collaborations. This will prompt my career
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Synthetic Quantum Many-Body Systems' (SQMS).

assistant: **Innovation**

This proposal shows a new path to explore frontiers in quantum many-body physics using degenerate atomic gases. We will address fundamental open questions, create novel quantum-many body systems and seek applications beyond the realm of quantum gases. A two-component Fermi gas in an optical lattice is a unique realisation of the Fermi-Hubbard model and it is intimately linked to elementary concepts and open questions in many-body physics. We will develop novel tools for continuous cooling and detection of fermionic atoms in optical lattices. This will enable us to enter the anti-ferromagnetic phase and to study fundamental questions concerning the interplay between localization, coherence and spin-ordering in quantum many-body systems. An intriguing direction towards the creation of novel quantum many-body systems is the coupling of a strongly correlated quantum gas to an optical cavity. Here the cavity creates an effective long-range interaction with global character. This will bring together the physics of strongly-correlated systems and non-linear phenomena using a microscopically accessible system. In this highly explorative field we envisage, as a first experiment, a study of cavity-driven self-organization which may allow us to identify a novel form of a supersolid phase. Rather than investigating or manipulating the quantum gas using light we will also invert this approach and study the light after the interaction with a quantum gas inside a cavity. Using cavity opto-mechanical effects and a van der-Waals blockade by Rydberg atoms excited inside the cavity we will explore squeezing of the light and a novel photon blockade.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Quantum driven cybersecurity - advanced security for the Internet of Things', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

According to Cisco there will be 500 billion devices connected to the Internet by 2030. Despite this huge potential, growth is hampered by user fears of inadequate security. The biggest quoted barrier to IoT growth in businesses is security, and with good reason. IoT devices are often the weakest point in any network and the estimated economic cost of IoT attacks to the top five European economies is €3.8 billion each year.There is an urgent industry need for a robust, end-to-end security solution that can uniquely identify IoT devices and handle the major challenges in registering and managing billions of IoT devices.In response to this need, Crypto Quantique has developed a unique Key Provisioning Architecture, underpinned by a true Physically Unclonable Function (PUF) that exploits the phenomenon of quantum tunnelling to generate unforgeable cryptographic keys to secure data communications. Together, these provide the most robust End-to-End security possible, eliminating user’s security fears and unlocking the latent potential in the IoT market.Our technology can provide an unforgeable identity at the device level, elimination of costs associated with key injection and provisioning and bill of materials, and enable IOT enterprises to rapidly onboard and control their own devices via cloud service providers.Our solution is: - Fully integrated and end-to-end (Key Provisioning Architecture + hardware root of trust). - The end-user runs their own security management – there is no need to devolve trust and security to third parties - Cloud platform, hardware and microcontroller independent.By licensing our quantum PUF IP and monetising API calls to verify identity, we will create a €33 p.a. opportunity by 2025, creating 70 new European jobs.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Automated canceR-on-A-CHip orgaN-specific metastatIc spreaD' in the context of a Horizon Europe call.

assistant: **Objectives**

Despite the improvements in cancer treatments, diagnostic tools and prevention/early detection strategies, cancer is still a major public health burden as one of the 6 leading causes of death worldwide. In 2020, 90% of the 10 million deaths registered out of 19.3 million new cancer diagnoses were associated not with primary tumors but with the secondary ones generated by the metastatic process.The complex time-dependent chain of events and cascades of biophysical and biochemical factors regulating tumor metastasis cannot be replicated using conventional in vitro cell models (such as transwell invasion and scratch/wound healing assays) nor in vivo animal models. The scientific and medical communities are striving to better understand the steps of metastatic spreading to devise strategies to stop its occurrence, especially in pediatric oncology, as in the case of Neuroblastoma, the most common and difficult to treat among tumors of preschool age (15% of pediatric oncology deaths).To solve these limitations we propose ARACHNID, a unique, multiplexed, automated, and increased-throughput multi-organ on a-chip platform conceived around the complex process of cancer metastatic spread. The project's potential for breakthrough innovation resides in its unique capabilities, promising to accelerate research, reduce costs, and contribute to the development of more effective cancer treatments.The ARACHNID project aims to explore and prove the technical-commercial potential of our proprietary tumor-metastasis-on-a-chip (TMOC) platform, starting from pediatric tumors and extending the application to adult cancers, involving Biogenera, biotechnological SME operating the pharma NB domain, as a testbed and early adopter.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Green Economy by Digital and democratised Energy Markets enabling the Active Consumers' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Enabling the energy transition is an urgent measure needed to mitigate climate change. However, the integration of increasing distributed renewable energy sources is causing an imbalance between generation and demand, grid congestion and price volatility. It is crucial to digitalise the grid and empower the consumers to reduce the impact of these effects of the energy transition. Demand Side Flexibility (DSF), managed through new players that aggregate the offer of the consumers, the Aggregators, is an innovative business model emerging in all the energy markets in Europe. The market opportunity is increasing at 21.5% CAGR to reach an available market value of €16.7B in 2027 in the EU. BAMBOO is a Software-as-a-Service platform based on Artificial Intelligence that allows Aggregators and Energy Retailers to offer DSF in the energy markets in an automated and dynamic manner. For the first time, these industry players can predict the demand and the flexibility of their client’s portfolio to offer it in real time.BAMBOO will facilitate the easy creation of new companies that aim to enter the market of DSF as aggregators, such as Energy Services companies, Infrastructures Companies, Industry Groups or Energy Communities. Therefore, BAMBOO will significantly impact the digitalisation of the European energy system and accelerate the penetration of renewable energy sources in the grid.The company is co-founded and led by Cristina Corchero, CTO, who is committed to bringing her knowledge and expertise acquired as a researcher to the market. Her professional career and female leadership has been recognised with outstanding awards; moreover, she has appeared on TV and media to talk about energy in plain language to the citizens. Thanks to Women TechEU, Cristina aims to improve he
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Pathoecology of Vibrio cholerae to better understand cholera index cases in endemic areas' (CholeraIndex).

assistant: **Concept**

Cholera is one of the oldest infectious diseases known and remains a major burden in many developing countries. The World Health Organization estimates that up to 4 million cases of cholera occur annually. The transmission of cholera by contaminated water, particularly under epidemic conditions, was first reported in the 19th century. However, early volunteer studies suggested that an incredibly high infectious dose (ID) is required to produce disease symptoms, in contrast to most other intestinal pathogens. Therefore, the mechanism of infection of index cases at the onset of an outbreak is unclear. This proposal aims to fill this knowledge gap by studying how the environmental lifestyle of the causative agent of the disease, the bacterium Vibrio cholerae, may prime the pathogen for intestinal colonization. We hypothesize that one of the natural niches of the bacterium (chitinous surfaces) fosters biofilm formation and provides a competitive advantage over co-colonizing bacteria. As an adaptive trait, passage of chitin-attached sessile V. cholerae through the acidic environment of the human stomach might be vastly facilitated compared to planktonic bacteria. Moreover, interbacterial warfare exerted by V. cholerae on these biotic surfaces may help the pathogen overcome the colonization barrier imposed by the human microbiota upon ingestion. The mechanism by which V. cholerae leaves the sessile lifestyle and the regulatory circuits involved in this process will also be investigated in this project. In summary, our goal is to elucidate the environmental community structures of V. cholerae that may enhance transmissibility from the ecosystem to humans in endemic areas resulting in the infection of index cases.


**Keywords:** Vibrio cholerae,  opportunistic pathogens,  ecol
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'RESPIRE: Planetary Breathing in Asphyxiating Times', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

We live in a time of multispecies suffocation. This is not a metaphor but a material process of contemporary multispecies living and dying on this planet. RESPIRE will address the fact that we do not know what this planetary multispecies suffocation consists of and will investigate how we can comprehend and transform it. It will do so through extensive fieldwork that includes collaboration with natural scientists, organisations, artists, and stakeholders. This approach is needed because the natural sciences study environmental problems but address them separately from social issues and do not offer an overall understanding of multispecies suffocation. The humanities offer important analyses of the effects of environmental and social degradation but no perspective for analysing planetary multispecies suffocation.RESPIREs hypothesis is that to describe and understand multispecies suffocation, we need approaches that address social and environmental issues as interrelated, and need to strengthen the scientific role of the humanities and arts, which specialise in challenging established norms and beliefs. We will analyse multispecies suffocation through the planetary lungs and their related problems: forests (deforestation), ocean (dead-zones  low oxygen areas), and soil (peatlands). Our inductive inquiry from humanities and art-based research perspectives will deliver fundamental research that will contribute to future research on social and climate change-related issues by producing a socio-environmental interdisciplinary approach and revealing the respiratory and multispecies dimensions of current challenges. RESPIRE will also develop new respiration-focused methodologies, concepts, and innovative pathways for a more breathable future. The project will further develop th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'NHM NIGHT4' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

NHM NIGHTS4 will deliver mass participation of a diverse public audience in a unique event to meet the Natural History Museum’s most dynamic and engaging international scientists in a festival of scientists in central London. With a rich and vibrant community of research scientists and PhD students, including research partners from around the UK (many of whom are accomplished science communication practitioners).  The NHM is well positioned to breakdown existing public stereotypes of researchers. This project will drive home to the public the role and value science and to inspire the next generation of young researchers. 8,000 participants will visit the Natural History Museum's London and Tring locations to be greeted by over 350 scientists delivering more than 150 different engaging activities and formats alongside professional educators in a fun and relaxed atmosphere. The impact of this event on the participants will be profound, and help foster a long term engagement with science.""