RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Legume-supported cropping systems for Europe'.

assistant: **Innovation**

This research will deliver knowledge and technology for the optimisation of the use of legumes in European agricultural systems and promote the partnerships needed to support the public policy outcomes sought. By integrating the Consortiums extensive set of existing field case studies, modelling and knowledge base, the project will test, validate and deliver novel cropping systems. This network of 18 case studies, in 12 countries, will be the focus of interaction with farmers, SMEs, other businesses, and policy makers. Outputs will include system-optimised cropping plans for each pedo-climatic region, input into existing farm-planning tools, local on-farm demonstrations, a socio-economic analysis that will enable local economic assessment of cropping systems, and an ecological assessment of the effects of relevant farming system changes on greenhouse gas and nitrogen budgets, biodiversity and soil health from the farm to the continental scale. A book on legume-supported eco-efficient farming systems covering all aspects of the use of legumes in Europe will be published. The research is planned around the appreciation of how nitrogen fertilisation and the production and use of plant protein lie at the heart of many of the global, regional and local environmental challenges arising from agriculture. The project will take a novel strategic approach to knowledge interaction and delivery, in order to enhance and pool existing knowledge platforms and databases. It will then deliver the results into the farming community, commercial use, and policy practice beyond the life of the project. The project will facilitate wide access to new and existing knowledge and technologies and it will promote awareness of the role of legumes in the development of sustainable supply chains and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The European hydrogen (based) society - target action A' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

The main objective of the proposal is to support the introduction of a safe and dependable hydrogen-based society in Europe through the creation of an enabling environment.Some important steps are:A) Identification of non-technical barriers and the proposal of policies and measures to remove and reduce existing barriers,B) Quantification of the technological, social, economical and environmental impacts of the introduction of hydrogen in the European society,C) To provide European decision and policy makers with a plan of action for the introduction of hydrogen in the European society,D) To foster the broad public awareness and debate as to the opportunities and challenges of the hydrogen society, stimulating the dialogue with all interest groups.The proposed action pretends to provide a starting point for making support for a clean hydrogen economy all across Europe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Data-protection toolkit reducing risks in hospitals and care centers' under Horizon 2020.

assistant: **Concept**

Health care is an essential service that uses a great deal of sensitive personal data which has a high black market value being a lucrative target for data theft and ransomware attacks.The EU NIS Directive (EU 2016/1148) and GDPR (EU 2016/679) will harmonize and improve information security in Europe. Both require relevant ICT infrastructure operators to perform risk assessments, introduce appropriate security measures to manage identified risks, and report security breaches. Unfortunately, risk-based approaches are notoriously difficult to implement in a consistent and comprehensive fashion. They depend on a high level of understanding of both cybersecurity and of the system or network to be protected, are labour intensive and costly and typically done by small teams. This is increasingly inappropriate as health care providers introduce IoT systems, cloud services and (in the near future) 5G networks to provide services in which patients are more engaged, may own some of the devices used, and want access in hospitals, on the move or at home. The ProTego project will develop a toolkit and guidelines to help health care systems users address cybersecurity risks in this new environment by introducing 3 main advances over current approaches: Extensive use of machine intelligence: a combination of machine inference exploiting a priory knowledge for security-by-design, and machine learning from data for run-time threat detection and diagnosis; Advanced data protection measures: advanced encryption techniques and hardware based full memory encryption, and multi-stakeholder IAM to control access to and by user devices, to protect data at rest and provide ultra-secure data exchange portals; Innovative protocols for stakeholder education: using security-by-design analysis to tar
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'A decision support system for mitigation of drought impacts in the Mediterranean regions' (1994-1998).

assistant: **Innovation**

The main objective of the research is the development of a Decision Support System (DSS), aiding decision makers in the operation of water supply systems under drought conditions, determining the most effective delivery policies for irrigation; in particular, the core of DSS will include three connected modules aiming to :a) identify the regional drought events and determine their characteristics (duration, deficit intensity, etc.);b) determine the most effective irrigation scheduling under drought conditions by using an appropriate crop-water simulation model;c) define the operation rules for storage facilities of the water supply system and individuate a set of drought mitigation measures.A second objective is the identification of the main requisites and institutional framework for developing an appropriate scheme of Drought Watch System for Mediterranean countries.Expected OutcomeThree main results are expected :* the development of appropriate procedures to identify drought, to define irrigation scheduling and to simulate water supply system under drought conditions, to be connected in a Decision Support System;* the analysis of the applicability of the proposed procedures and of the DSS package to some irrigation districts selected in the Mediterranean semi-arid countries involved in the Project (Portugal, Tunisia, Italy, Jordan and Syria);* the definition of criteria and organizational structure of a Drought Watch System in the Mediterranean semi-arid regions.The research activities have been planned as follows :* Identification of drought characteristics, including the selection of the methodology to characterize severe droughts affecting large-scale water supply systems and the analysis of the variation of drought characteristics in Mediterranean areas on the b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Combining Process Intensification-driven Manufacture of Microstructured Reactors and Process Design regarding to Industrial Dimensions and Environment'.

assistant: **Innovation**

The ultimate ambition of COPIRIDE is to develop a new modular production and factory concept for the chemical industry using adaptable plants with flexible output. This concept will be superior, intellectual property (IP) protected, and enable a much wider spread of know-how and education of this skill-intensive technology. Key functional enabling units are new production-scale, mass-manufactured microstructured reactors as well as other integrated process intensification (PI) reactors realising integrated processes. This will lead to a substantial reduction in costs, resources & energy and notably improves the eco-efficiency. To ensure the competitiveness of European (EU) manufacturing businesses, PI technology / know-how is transferred from leaders to countries (and respective medium & small industries) with no exposure in PI so far, but with a track record in sustainability, and to the explorative markets food and biofuels. A deeply rooted base will be created for IP rights (Copyright, © = COPIRIDE) by generic modular reactor & plant design and new generic processes via ‘Novel Process Windows’, facilitating patent filing. Due to the entire modular plant concept comprising all utilities – far beyond the reaction & processual parts - a holistic PI concept is provided, covering the whole development cycle with, e.g., safety & process control & plant approval. Features, inter alia, are fast plant start-up and shut-down for multipurpose functionality (flexibility in products), sustainable & safe production, and fast transfer from lab to production & business (time-to-market). Industrial demonstration activities up to production scale with five field trials present a good cross-section of reactions relevant to the EU chemical industry. The economic impact in COPIRIDE is 10
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Strategies Targeting Thyroid Hormone in Athrophy Related Syndromes' in the context of a Horizon 2020 call.

assistant: **Objectives**

Skeletal muscle wasting is a devastating complication of many chronic diseases including cancer, diabetes, chronic heart failure and cystic fibrosis. Despite its medical importance, there is, as yet, no effective means to treat this condition. Therefore, an urgent challenge is to discover treatments able to prevent its onset and/or progression. Thyroid hormone (TH) is a major determinant of muscle functions, and thyroid dysfunctions are leading causes of many myopathies. An emerging concept in this field is that TH’s pleiotropic actions can be amplified or attenuated at cell level by the deiodinase enzymes that can increase (D2) or decrease (D3) the active TH concentration regardless of hormone plasma levels. Based on recent published and new preliminary data, our working hypothesis is that “amplification” of TH action/signalling in muscle is critical in determining the accelerated muscle catabolism that causes muscle loss in numerous diseases. On the contrary, attenuation of the TH signal facilitates the proliferation/survival of muscle stem cells and reduces atrophy. Using genetically manipulated mouse models of altered TH metabolism, STARS aims to dissect the role of TH in muscle fibers and stem cells during the wasting processes. The ground-breaking nature of STARS is the possibility of manipulating a local-acting mechanism that determines the tissue concentration of a diffuse endocrine signal (TH), which is a critical determinant of muscle wasting. We will use state-of-the art methodology and recently generated mouse models in the attempt to explore the therapeutic potential of novel mechanisms to lower the TH signature at a specific muscle level. Proof-of-principle studies will be conducted with novel hormone-peptide conjugates for targeted disease prevention and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Automated online monitoring & control to improve processes and decision making in cell and gene therapy manufacturing' under Horizon Europe.

assistant: **Concept**

Problem: Cell and gene therapies (CGT) represent a breakthrough in the treatment of a wide range of conditions. However, limited global manufacturing capacity owing to a lack of scalability prevents CGT from becoming widely available to patients: therapies are prepared individually at central facilities in a series of complex open manual steps. Variability is high, and a uniform manufacturing process is lacking. Automated, standardized, quality-controlled, and decentralized processes are urgently needed to scale out CGT manufacturing, bring down costs and enable treatment for millions of patients. True automation requires an understanding of what are known as critical process parameters (CPPs). Currently, manufacturing of cell therapies is carried out over several days, with limited access to knowledge of CPPs, often obtained through intrusive sampling methods. Innovation: We aim to enable in-line continuous monitoring of key cell culture parameters during therapy manufacturing. To do this, we will create a self-contained instrument that connects miniaturized biosensor technologies to a novel bioreactor to allow automation of the entire cell therapy manufacturing process in a closed system. The device will accommodate a disposable, single-use sampling unit that will ultimately be adaptable to any bioreactor. Our platform will carry out continuous, automated, and closed monitoring of a set of well-defined CPPs, as indicators of the overall state of the cell culture. We will select and refine our parameters and establish optimal ranges, as predictors of process outcomes and product quality, based on prediction algorithms and digital twin analysis. This will allow continuous process monitoring, while greatly lowering costs and risks associated with manual sampling. Our fir
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Development and validation of Source, Optics And Resist In Next Generation EUV lithography' (SOARING) under Fifth Framework.

assistant: **Objectives**

The objective of the current proposal is to carry out the research and development work necessary to provide a set of scaleable components for Extreme Ultraviolet Lithography (EUVL) and to validate their performances in producing sub-70 nm features on silicon using industrial compatible wafer processing technology. These components include a novel high repetition rate high intensity micro discharge pulse plasma EUV source, a set of matching multi-layer collection and projection mirror optics using an active mirror design and an optimised single layer EUV resist. The goal of the project includes optimisation necessary to provide the EU semiconductor industry with these components for future integration. The work will be carried out in a 36 months programme, by a trans-national team of 5 partners involving national research organizations and industrial SMEs in 3 countries, covering all the key areas of expertise required.Objectives:The road map of the world semiconductor industry demands the availability of a next generation lithography system by 2005 for commercial production of microelectronics with feature size below 70nm. Currently EUVL is one of the most favoured options. While engineering test stand on EUVL has been established to evaluate the technology, a number of key issues remain to be resolved for industrial application. The objective of the current proposal is to carry out the R&D work necessary to provide a set of scalable components for EUVL and to validate their performances in producing sub-70nm features on silicon using industrial compatible wafer processing technology. These components include a novel high rep rate high intensity discharge plasma EUV source, a set of matching multi-layer collection and projection mirror optics and optimised EUV resists.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Innovative Architectures, Wireless Technologies and Tools for High Capacity and Sustainable 5G Ultra-Dense Cellular Networks' under Horizon 2020.

assistant: **Concept**

The fifth-generation (5G) is coming.Quo vadis 5G?What architectures, network topologies and technologies will define it?Are methodologies to the analysis, design and optimization of current cellular networks still applicable to 5G? 5Gwireless is the first integrated and multi-disciplinary training-through-research network of ESRs and Senior Supervisors fully committed to re-architecting current cellular principles aiming at making 5G a reality, it will define and optimize radically-changing architectures and technologies leading to a wholesale re-thinking of cellular operational principles & architectures, network topologies, transmission technologies and methods to their analysis, design and optimization. It will recruit 15 ESRs having the objective of conducting top-notch research at national, European and international levels.ESRs will receive personalized training and will conduct theoretical and applied research on fundamental challenges to the development of 5G systems and networks. According to the 5G Public-Private Partnership (5GPPP) recently formed by the EU, 5G networks need to be designed, engineered and optimized by relying on innovative technologies capable of providing 1000 times higher capacity and a 90% reduction in energy consumption compared to the status quo.Such a fundamental and radical paradigm-shift in network design and architecture requires cross-sectoral skills&background and can very unlikely be realized by researchers that have not received personalized training on innovative technologies and adequate methodological tools to their analysis.5Gwireless' mission is to create a vibrant EU-based training and research environment for young researchers aiming at designing architectures, systems and algorithms for building the 5G cellular network of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Study and optimisation of an ALL AIR" ice storage package for air conditioning systems"' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

The aim of this project is to develop and set up a new design for air conditioning systems. One of the technologies used for large air conditioning systems, is the storage of ice enclosed in plastic balls. Those ice balls have a special design so that they can expand during the freezing of water into ice. They are stored in large tanks containing a solution of water and glycol. One part of this solution is pushed away in an expansion vessel during the expansion stage of the balls. In the new system, the ice balls will be redesigned in order to be more rigid, and also to provide a better heat exchange rate with the outer fluid. Moreover, they will be filled with a foam that will absorb the expansion of ice. This should prevent from using a bath of water and glycol to store them, and will give rise to two major improvements: - The ice balls may be stored in dry stacking in light structure tanks. - The use of air as cooling fluid: This last innovation will simplify the design of the whole air conditioning system, using only one circuit for the cooling fluid, instead of the three circuits generally used. The aims of the project will be to optimise the material, shape and dimensions of the ice balls, to assess the feasibility of the heat exchange system, and to design the manufacturing process for the air conditioning package.