RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Nature based interventions for improving health and well-being' in the context of a Horizon Europe call.

assistant: **Objectives**

NATURELAB will contribute to increased recognition, promotion and use of green and blue spaces as health care providers, by investigating the benefits of nature-based therapies (NBT) to promote well-being and support health prevention & rehabilitation.Around 4000 participants from 15 Experimental Sites and 4 Demonstrator Fellows located in rural, coastal, and urban areas of five European and Latin American countries (PT, EL, NL, DE, and PE) will experience the NATURELAB NBT programmes. The participants will ensure a representative sample of gender, age and socioeconomic status. The geographic locations comprise a variety of climate, nature (green and blue), ecosystems, biodiversity, cultural, policy and administrative scenarios. The health issues that will be addressed include physical (hypertension) and mental conditions (depression), among others.NATURELAB proposes an innovative approach to contribute to resilient communities, by enhancing the green and blue areas' benefits - as the resilience to climate change, the promotion of biodiversity and urban water management, and addressing as well air pollution and noise levels. The project will deliver, among others: i) NBT programmes tailored to population with different needs; ii) Portfolio of indicators to classify the health potential of nature & Guidelines to analyse the health benefits of green areas as required by natural capital accounting; iv) Guidelines for the creation and management of private and public healing gardens, horticulture/gardening spaces merging climate resilience and environment sustainability; iv) Programme Guide for funding scheme to support NBT in the health sector and v) Guidelines to promote the integration of NB care in the public health sector. Around 600 health professionals worldwide will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Network for Evaluation of Propagation and Interference Training', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The widespread use of modern communication systems, the higher penetration of automated systems in automotive engineering, surgery, high-tech machines etc., the higher complexity present in those interconnected systems and the higher dependence of modern society on technology, creates an urgent need to recruit and train researchers in electromagnetic compatibility. This interconnected systems-of-systems are creating a complex electromagnetic environment in which interoperability of the electrical and electronic equipment has to be achieved. A highly trained cadre of engineers is required to lead in this area and the aim of this initiative is to train such people, connecting them to the industry for implementation of the new acquired and developed knowledge and experience. The NEPIT consortium has been brought together not only to train qualified researchers but also to provide the fundamental research that underpins future technological developments. The multidisciplinary multinational doctoral training program will provide the trainee researchers with a complete broad experience and at the same time allows them to develop and eventually lead their focused area of research. The program will focus on the development of novel methods to model, simulate, design, evaluate and test complex systems for electromagnetic compatibility. NEPIT will also develop corrective economic measures for safe, reliable, efficient and greener complex systems. Specific innovations expected to be achieved through NEPIT are methodologies to optimize the design, to reduce risks, and to improve the testing of complex high-tech systems. Dissemination methods to realize optimal impact will include scientific publications, presentations and workshops, summer schools, training of engineers within indu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Deterministic coupling between SITE-controlled, dilute nitride-based LighT Emitters and tailor-made photonic-crystal structures' (SITELiTE) under Seventh Framework.

assistant: **Objectives**

The establishment of a simple, reliable method for the deterministic coupling of nm-sized light emitters with photonic crystal (PhC) cavities is expected to propel the field of nanophotonics into a new era. Indeed, the possibility to place single quantum objects at arbitrary points of a PhC structure would allow for the realization of complex photonic circuits, integrating single- and entangled-photon sources as well as PhC routers, switches, and delay lines. The SITELiTE project will position itself at the forefront of this forthcoming revolution, through the exploitation of a novel method for the fabrication of site-controlled nano-emitters (quantum dots, but also individual impurity complexes) by spatially-selective hydrogenation of dilute-nitride materials, recently demonstrated by the Host Institution [the G29 laboratory of Sapienza University of Rome; see, e.g., Adv. Mater. 23, 2706 (2011)].The PhC cavities employed by the present project will be designed with an innovative semi-analytic method, recently introduced by the fellow, Dr. M. Felici [Phys. Rev. B 82, 115118 (2010)]. Through the definition of a direct relationship between the target electromagnetic field distribution and the dielectric constant of the cavity supporting it, this method eliminates the need for the cumbersome, computationally demanding trial-and-error procedures that currently hinder further developments in the field of PhC cavity design. Initially, this approach will be applied to cavities supporting modes with Gaussian envelope function and ultra-low cavity losses. Then, the project will focus on the engineering of PhC structures with more complex mode distributions, including systems of coupled cavities and PhC cavities with disorder-insensitive properties. The designed PhC structures, i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'A new integrative framework for the study of fish welfare based on the concepts of allostasis, appraisal and coping styles' (COPEWELL) targeting Seventh Framework.

assistant: **Abstract**

COPEWELL aims to provide a better understanding of the underpinning mechanisms and basic knowledge about the physiology, biology, and behaviour of fishes and to give a deeper understanding of the basic mechanisms involved in  coping styles.  We will use an innovative hypothesis-driven multidisciplinary approach that aims to explore the links between brain function, behaviour and adaptive plasticity (WPs 1 and 2). Underlying mechanisms will be addressed by localising key elements of the stress-responsive serotonergic and learning and memory systems in the telencephalon, and for the first time also analyse rates of brain cell proliferation, neurogenesis, and expression of genes controlling other aspects of brain function, as learning and memory, in fish expressing different coping styles. The project will also focus on the understanding of how animals experience their world, based on appraisal theory and experimental studies of appraisal mechanisms in farmed fish, and not simply on the description of animal behaviour or stress responses (WP2 Appraisal). COPEWELL will further study the ontogeny of brain function and neuroendocrine stress responses in the call species Atlantic salmon (Salmo salar), European sea bass (Dicentrarchus labrax) and sea bream (Sparus aurata), and will provide new insights on the interrelations between different relevant husbandry practices, plasticity of brain function and stress response during early ontogeny. COPEWELL will explore potential consequences of early life stress experiences on the welfare and quality of juvenile fish, substantiate the concept of allostatic stress regulation in fish and determine thresholds between eustress that are considered positive for welfare and distress that can have severe negative consequences for fish welfar
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Neuroscience in the real world: Representation of position, direction and environmental borders in the hippocampal formation of bats navigating outdoors on a remote oceanic island'.

assistant: **Innovation**

Navigation is a key behavior, studied by multiple research fields. In ethology, wild animals are tracked outdoors using GPS tags as they navigate hundreds of meters or kilometers. In neuroscience, experiments are very different: laboratory animals are tracked inside small ~1×1-meter boxes, while recording the activity of navigation-related neurons – such as place cells, grid cells, head-direction cells, and border cells.  However, it is unknown whether these spatial neurons, as studied in small laboratory-sized environments over 50 years, are relevant to large-scale navigation in the real world – outdoors.   In this proposal we will address this major gap, by conducting the first ever neural recordings from the brain’s “navigation circuit” in animals navigating outdoors. We will implant bats with tetrode microdrives, and will release them to fly on a remote, uninhabited oceanic island.  Using custom wireless neural-logger and GPS, we will study the neurobiology of navigation – for the first time – in the real world.   We will explore: (1) How place cells and grid cells represent large natural habitats outdoors?  (2) How these neurons encode 3D space – and in particular, altitude – in an open environment without a ceiling?  (3) Are there border cells in animals navigating outdoors – e.g. border cells encoding the land/sea border, which is the “end of the world” for the bat?  (4) Do head-direction cells represent a geographical compass? Specifically: do they maintain their head-direction tuning across all geographical locations on the island, and irrespective of moon movements?  Preliminary experiments that we conducted on Latham Island, Tanzania, showed the feasibility of this project. We will record the same neurons outdoors and indoors, in a flight-tent on the island.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'ERA-NET for Coordinating Action in Plant Sciences (ERA-CAPS)' to be submitted under Seventh Framework.

assistant: **Abstract**

Plant sciences face important challenges at the European and global scale due to a burgeoning world population that requires sustenance. Reliable production of high-quality and safe food, feed and renewable Carbon supplies for green chemistry, without the use of excess land, energy, water, pesticides and chemicals is therefore essential.To ensure that we have the scientific understanding to again revolutionise agricultural capabilities to deliver higher yields with lower inputs in a changing climate, we propose a network focusing on Coordinating Action in Plant Sciences (ERA-CAPS). This will unite the scientific and economic capabilities of member states and enable the coordination of sustainable transnational plant science research programmes.ERA-PG (2004-2009) successfully initiated a programme to structure the scientific and technological basis for plant genomics programmes in Europe. This has fostered the development of the common knowledge base necessary to build coherent transnational policy frameworks. However, if transnational cooperation and resolute mutual goals in the plant sciences are to be firmly embedded in national policies and processes, these foundations must be strengthened and expanded.To bring this about ERA-CAPS will pursue the development of a common agenda for plant science in Europe and create a joint research programme. ERA-CAPS will also facilitate data management, access and sharing solutions. Through external engagement ERA-CAPS will enable interaction between researchers, funders and relevant European initiatives, and assist in the systematic exchange of information to facilitate the expansion of the network and the involvement of new members and affiliates.Such a network will significantly help plant sciences address both current and futur
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Recovery of Tungsten, Niobium and Tantalum occurring as by-products in mining and processing waste streams' (TARANTULA).

assistant: **Concept**

The extraordinary properties of refractory metals, the unlikeliness of their future substitution and their use in booming industries will sustain a high EU demand for tungsten (W), niobium (Nb) and tantalum (Ta). Despite all three being classified as Critical Raw Materials (CRM) by the European Commission (EC), fractions of these indispensable metals are dissipated as by-products in mining waste streams as well as process scrap. To stimulate their recovery from such complex, low-grade resources, TARANTULA will develop a suite of cost-effective, scalable and eco-friendly – bio-, hydro-, iono-, solvo-, pyro- and electro-metallurgical – processes with high selectivity and recovery rates. These novel technologies, each representing an alternative for one or more process steps of state-of-the-art (SoA) processing lines, will form new routes towards market-ready metals, metal oxides and metal carbides. Flexibility will be the cornerstone of the overall process flowsheet to enable recovery of all three elements (W, Nb, Ta), thereby minimising the CAPEX required for future processing installations. Following systematic research and innovation activities at lab scale, the envisioned technologies will be brought to TRL3-5 and, based on performance, validated at prototype level by experienced industrial partners. In parallel, future by-product recovery will be supported by carrying out a comprehensive identification and assessment of existing un/underexploited secondary sources of W, Nb and Ta. The generated information – in compliance with all pertinent laws and regulations - will feed into the Raw Materials Information System (RMIS) which will boost the impact of the project far beyond the current consortium. Finally, TARANTULA will blueprint tailored Communication, Disseminatio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Cellular production of wnts, secreted growth and differentiation factors and their use as coordinators of organ specific stem cells' (1998-2002).

assistant: **Innovation**

Wants encode secreted signals that regulate growth and cellular differentiation of various stem cells during embryonic development. No useful systems are available to express the Wants in their biologically active form and to maintain the stem cells undifferentiated in vitro. We will develop efficient recombinant production applicable to any given Want. The biological activity of the produced Wants will be tested in vitro cellular readout systems and in early Venous embryo. The consortium members have identified that Wants are important maintenance factors of stem cells in many different organ system. The Wants, their receptors and signal transudation components will be screened in these systems. The biological activity of the recombinant Wants will be tested in their capacity to keep the cells pluripotent in vitro and if they play a role in driving cells to specific cell lineages.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Design and development of advanced NAnomedicines to overcome Biological BArriers and to treat severe diseases'.

assistant: **Objectives**

Many therapeutic targets are shielded behind biological barriers, limiting the possibility to reach them with conventional drugs or diagnostic probes. Biological barriers are even more problematic for most biological pharmaceutics, such as recombinant proteins, antibodies and gene therapeutics. The most promising solution to this challenge is the use of nano-vehicles for specific targeting and delivery. The aim of NABBA is to form European early stage researchers (ESR) with cutting-edge scientific knowledge in the field of nanoparticles (NP) for biomedical application, able to cross biological barriers. For this aim the project will train ESRs, focusing on key aspects of nanobiotechnology: (i) design and chemical synthesis of different types of NPs, (ii) related techniques of detection and characterization, (iii) strategies of loading, targeting and delivery of drugs or diagnostic probes; (iv) proof of principle of pharmacological activity including pharmacokinetics and biodistribution. As a peculiar feature of NABBA, strong emphasis will be devoted to molecular mechanisms ruling biological barriers under physiological and pathological conditions, in order to develop novel nano-technological expedients for their crossing. Strong emphasis will be devoted to advanced chemistry issues, enabling new synthetic strategies either for NP assembly or functionalization. Different biological barriers will be addressed. ESRs will strongly benefit from a network of internationally recognized scientists in the field of chemistry, nanobiotechnology and nanomedicine, and the participation of companies with relevant interests and expertises in the field. The planned cooperation programs between Academia and Industries will allow the circulation of ESRs and this will give them the opport
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The role of chromatin insulator elements in the control gene expression' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Chromatin insulators allow genes to maintain independent programmes of expression through the establishment of fixed chromatin boundaries. Vertebrate insulators have been found to regulate the expression of genes with functions from growth control and development to X-inactivation. The properties of insulators have been extensively characterised, but their mechanism of action is largely undetermined. The HS4 element from the chicken b-globin locus is the paradigm vertebrate insulator. Flanking transgenes with HS4 has proved useful in the generation of many transgenic animal and cell lines, by allowing uniform transgene expression in all tissue types.The aim of this proposal is to determine the mechanism(s) of insulator action. In my postdoctoral studies at the NIH (USA), I identified the first known insulator-binding proteins from vertebrates. I have recently taken up a lectureship at the University of Glasgow where I am establishing an independent research group to study chromatin insulator elements and gene regulation. I have minimal start-up funding, so I am applying for an IRG to help establish my research programme, thus promoting my re-integration into the European Research Area.The proposed work will focus on a new protein, called BGP1 that interacts with several binding sites within the HS4 element. BGP1 binding sites are required for the barrier activity of HS4. BGP1 binding sites are also required for the prevention of CpG DNA methylation, an epigenetic determinant of stable gene silencing. This is of broad interest as the promoters of tumour suppressor genes become aberrantly methylated and transcriptionally silenced in cancer. It is conceivable that BGP1 recruits a factor that mediates immunity from DNA methylation. I will purify BGP1-interacting proteins in