RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Education policies that work:  A context-sensitive ‘big data’ approach', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

In the last decades, profound socio-economic changes have posed unprecedented challenges to the traditional centralised model of state-provided education. This has led many countries to adopt neoliberal educational policies (NLPs) promoting school autonomy, competition and accountability as leverages for school effectiveness. Yet, given increasing societal inequalities, we are also witnessing a resurgence of democratic inclusive educational policies (DIPs) with egalitarian aims. Although these different policies can coexist, they have so far been scrutinised separately. EDUPOL develops the first comprehensive comparative analysis of the interplay between NLPs and DIPs. By building on the concepts of policy configurations and context-specific effects, the project proposes a paradigmatic shift from the focus on what works to what combinations of policies work for whom and in which circumstances. It pursues four key aims: 1) to investigate the trends and diffusion of NLPs and DIPs across the globe in the last four decades; 2) to assess their effects on quality and equality in students (cognitive and socio-emotional) competencies and civic engagement; 3) to map within-country school-specific policies; 4) to uncover the heterogeneous effects of school-level policies across schools and territories. EDUPOL builds a novel macro-longitudinal dataset of educational policies and integrates insights from international repeated cross-sectional data, ground-breaking Italian big data (millions of student records, textual data from school reports, administrative archives, satellite data), student population panel data and qualitative interviews with key school actors to achieve its ambitious objectives. By combining qualitative comparative analysis, spatial panel regression, flexible m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Safety-ENhancing Innovations for Older Road userS' (SENIORS) under Horizon 2020.

assistant: **Objectives**

European countries face great challenges because the demographic structure in the EU is changing rapidly, due to reducing birth rates and increasing life expectancies. In 2012, 17% of Europeans were aged 65 and older and in 2020 this will rise to 28%. Meanwhile, the mobility needs of the elderly are also changing. Maintaining a driver's licence is an important issue of independence today, both for males and females. Also technological developments like the introduction of e-bikes enables access to other means of transport.These demographic and behavioural changes are of growing concern to mobility and road safety. While accident data show a decreasing number of fatalities and serious injuries on EU roads, recent data from the ERSO show an increasing proportion of elderly in the fatality statistics.  This trend is a serious threat to the achievements of recent decades and poses a challenge that must be addressed to meet goals set for further reduction of road fatalities. Furthermore, there is an increasing rate of obesity in EU populations, which introduces changes in injury patterns and risks. The SENIORS project focuses on the protection of elderly and obese road users also by transferring nowadays younger generations’ safety standards. The objective is to develop the required understanding of accident scenarios, injury mechanisms and risks and to implement these findings in test tools and test and assessment procedures. An integrated approach considering the elderly in multiple transport modes is applied to reduce the portion of elderly fatalities. The small-scale project focuses on providing tools to encourage wider adoption of advanced restraint and pedestrian protection systems improving the protection of older and obese vulnerable road users. The activities consol
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'An exosome-based therapeutic approach against chronic inflammation' in the context of a Horizon 2020 call.

assistant: **Objectives**

DNA damage triggers the activation of innate immune signaling leading to chronic inflammation and the premature onset of e.g. rheumatoid arthritis, diabetes, metabolic diseases and neurodegenerative disorders in man. Based on our ERC consolidator program DeFiNER, we recently discovered that persistent DNA damage triggers the innate immune system stimulating broad inflammatory and antiviral immune countermeasures that lead to chronic inflammation and the premature onset of severe metabolic complications and neurodegeneration in mice. Here, we propose a sophisticated a therapeutic anti-inflammatory strategy aimed at lowering chronic inflammation in preclinical animal models with pronounced metabolic diseases or neurodegeneration. Unlike available anti-inflammatory therapies, the proposed therapeutic approach is non-immunogenic, allows the therapeutic cargo to circulate for extended periods within the body and to cross the blood brain barrier with no biocompatibility complications and minimal to no inherent toxicity issues in mice. This novel strategy provides, therefore, the means towards an innovative medicine that will effectively address real but unmet therapeutic needs for a wide range of devastating diseases associated with chronic inflammation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Contact Lenses for the Ear - Invisibly providing natural hearing experience for Europe's 52 million hearing-impaired people' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Vibrosonic is a young high-tech company in medical industry, based in Mannheim (Germany), with currently 11 employees. Our vision is to improve the life quality of 52mn. Europeans who self-reported to experience hearing loss. More than 45 million of them refuse to make use of hearing aids and remain untreated despite the physical, mental and social consequences. Main reason for this is the visibility of hearing aid devices and the perceived social stigmatisation. And even the vast majority of those wearing hearing aids are unsatisfied with current state-of-the-art technology. They lament that they are not able to hear naturally. This means, that they have difficulties in locating the origin of noises (as they hear noises only through the integrated speakers of current hearing aids which is particularly dangerous in traffic), identifying voices in groups of people or hearing sound distortedly. In addition, wearing comfort is low: hearing aids have to be removed regularly for charging, cleaning or while showering or sleeping, and they often cause ear pressure, itching, pressure marks and sore points. Therefore, we invented and developed the world’s first contact lens for the ear based on microsystem technology and the piezoelectric principle – the Vibrosonic Hearing Contacts. In contrast to all other hearing aids, our system is so small that it can be directly placed on the eardrum instead of outside the ear. And in contrast to all other hearing aids, our system does not use speakers to transport sound via the air column in the ear canal: the Hearing Contacts stimulate the eardrum directly by bending and contracting under the influence of electric impulses. This enables the hearing-impaired person to hear naturally like not impaired persons.The system targets at Europe’s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Competitive Advantage for Process-intensive industries by SCheduling with Heuristics-EnhanceD simulation & optimisation' (CAP-SCHED) targeting Seventh Framework.

assistant: **Abstract**

A competitive weapon for companies in process-intensive industries such as the chemical industry, is effective mastery of supply chain management from raw material to end product so as to improve efficiency, effectiveness, & profitability. However, in flow scheduling, the human operator can be overwhelmed by the complexity of the problem. CAP-SCHED involves developing a new intelligent scheduling system for companies in continuous/semi-continuous process industries. The innovative solution uses a multi-agent framework to combine 2 existing approaches which, individually, are inadequate to improve scheduling. However, combining both approaches offers significant improvements to implement more profitable solutions to scheduling problems, with better account taken of constraints. The 2 approaches are: 1. Simulation through trial & error: * The scheduler instructs the system to calculate all material flows in terms of quantity & quality from up- to down-stream throughout the plant; * If infeasibility occurs (e.g. capacity limitation…) then the planner readjusts parameters in trial & error mode to reach a feasible solution. and 2. Algorithmic constraint solving: * the problem is represented as a mathematical model & the system attempts a solution, helped by heuristic guesses so as to guide the search algorithm via domain knowledge. The new idea is to allow full interaction with the system via a Graphical User Interface as if running in simulation mode, & to translate instructions, when the value of an operating parameter (or the starting date of an event…) is fixed, in terms of constraints imposed in the mathematical model. Thus, the person responsible for scheduling can choose to fix variable values, and to let the system find those left free so as to reach a feasible solut
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'A Digital Spatial Approach to Decoding Domestic Art Display across Early Modern Antwerp Society' (SPADArt) under Horizon Europe.

assistant: **Objectives**

The SPADArt project addresses a significant gap in our understanding of early modern European art by reconstructing the private domestic settings in which artworks were originally displayed and enjoyed. Despite the prominence of these artworks in museums today, little is known about their original spatial and material contexts such as the interiors and objects that surrounded them. This gap in our knowledge makes it impossible to fully understand the cultural and social implications of art display in historical daily lives and it hinders effective communication of these insights to the public in museums.To bridge this gap, SPADArt develops a holistic spatial methodology that adds a critical spatial dimension to study artworks within their original contexts at home. Focusing on early modern Antwerp, the project leverages underexplored sources from the host institute, including extensive databases of probate inventories and digital historical maps, in combination with the researcher’s expertise in art history and digital methods. Drawing on these areas of expertise, SPADArt will mine large inventory databases and collect architectural evidence to develop typologies of premodern Antwerp houses in schematic 3D models and identify object ensembles around artworks and their spatial positions in houses across social strata. These outcomes will be integrated into a novel spatial methodology, which will be applied across case studies analyzing class-based and gender-specific art display as well as the role of art in religious practices at home.SPADArt will add the critical yet missing expertise in material culture to the researcher’s skillset, providing a crucial foundation for future research and an independent research career. SPADArt's spatial methodology will offer new persp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Biological Determinants of ILC Reactivity for Immune Responses in Health and Disease' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Innate lymphoid cells (ILC) are a newly described family of hematopoietic cells that lack antigen-specific receptors but can be activated to promptly produce large amounts of cytokines (including interleukin (IL)-5, -13, -17A, -22, TNF-α and interferon-γ) and thereby contribute to the immediate, first-line immune defense against viral, bacterial, and parasitic infections. ILCs include the previously described natural killer (NK) cells and have a similar 'natural' effector function which is immediately available during immune responses and prior to that of adaptive immunity. Three groups of ILC (ILC1, ILC2, ILC3) have been described that share biological activities of T helper (Th)1, Th2 and Th17/22 subsets and CTL. ILCs are active during both fetal and adult life and play important roles in the homeostasis of mucosal and non-mucosal tissues. Nevertheless, how ILCs are integrated into ongoing immune responses remains unclear and this knowledge is a prerequisite for harnessing the clinical potential of these immune effector cells. This proposal will investigate critical checkpoints that can regulate ILC reactivity for immune responses in humans and mice. The four proposed objectives will be addressed using a combination of cutting-edge technologies including innovative mouse models that can report on ILC biology in vivo, single cell transcriptional and functional analysis of diverse circulating and tissue human and mouse ILC subsets, ‘digital’ pathogen-dependent ILC activation approaches and computational analysis of large immunological datasets from healthy, normal human individuals. Collectively, these complementary studies will shed new light on the biological determinants which condition ILC reactivity in humans and mice. Understanding how the threshold of ILC respons
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'INTELLIGENT PRODUCTS MANUALS' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

The project aims to develop a methodology for provision of intelligent decision support throughout the product life cycle, from product installation, through its maintenance and diagnosis to its dismantling and recycling.The main objectives of this project are:- to develop a methodology for the creation of intelligent product manuals (IPMs) that integrate complementary product data and companies' expertise.- to develop an information framework for structuring all product related data.- to enable medium and small size enterprises in the CEE to gain access and adopt advanced tools and techniques for knowledge representation, acquisition, visualisation and retrieval. These new advanced information technologies will allow the SMEs to structure and systematise their companies' expertise and replace traditional product manuals with interactive systems for intelligent information provision and decision support.- to develop IPM prototypes for two selected products (one from each industrial partner).- to enable SMEs in the CEE to significantly improve the efficiency and quality of their customer support. As a consequence, their export capabilities and market positions will be strengthened.The main innovation of the PROMANUAL project lies in the application of a large number of separate state-of-the-art techniques and tools and also in the integration and utilisation of complementary knowledge relating to companies' products and expertise.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Concerted action on formal approaches to risk assessment for seaborne transport in European waters'.

assistant: **Concept**

One of the main objectives is to bring together experts from all relevant parties involved in European shipping. This network would establish a unique knowledge about the assessment of safety and environmental impact of ships. A common understanding will be created in Europe of how approaches to risk assessment and environmental impact can be applied to shipping, e.g. as adequate basis for future safety and anti-pollution regulations or for more flexibility in ship safety design. The concerted action intends to contribute to the harmonization of European activities in regulating shipping transport. In order to serve those general goals the concerted action has the following particular objectives. A common knowledge about the current state of the art of assessing risk and environmental impact of ships will be established. Contacts to relevant initiatives and project consortia investigating into formal risk assessment approaches will be established and maintained to collect the different view points. Other industries will be reviewed with respect to the applicability to ships. It is envisaged to identify all the aspects which have to be considered when assessing risk and environmental impacts from ships. This involves for instance the availability and applicability of assessment methods, the problem of implementing the human factor, requirements for data format and collection, consideration of the environmental sensitivity of marine areas. Other important aspects to be clarified relate to objectives and requirements to be met from potential future users of formal risk assessment approaches, such as shipping industry, flag states and administrations involved with waterborne present and future traffic regulation. On the way to a commonly understood and accepted approach in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Protein-excipient Interactions and Protein-Protein Interactions in formulation' in the context of a Horizon 2020 call.

assistant: **Objectives**

The revolution of biotechnology has led to the creation of various types of therapeutic biologics with the potential to provide treatment for new chronic and malignant diseases. Though the potential advantages of biologics lay in their high specificity and potency combined with few side effects, their formulation still remains a large challenge to pharmaceutical scientists. This is in part due to the complex, not-well understood relationship between the physicochemical properties of proteins and formulation conditions required for protein stability. A comprehensive understanding of the molecular mechanisms behind protein stabilization and solubility would provide the formulation scientists with knowledge of the interplay between formulation and stability that in turn could potentially make formulation development faster, cheaper and less labour intensive than the currently used broad screening approach. Understanding the susceptibilities of formulations to protein aggregation and denaturation can reduce the response time to for instance product failure. Few universities in Europe have formulation of biologics as a scientific subject. Consequently, the pharmaceutical industry is forced to train scientists - a challenge for larger companies, and an insurmountable task for smaller companies. Scientists in the field of structural biology, biophysics, protein formulation and stability have formed a consortium to systematically map physicochemical properties of biologics, formulation conditions and protein stability. The main objective of the consortium is to provide a new generation of innovative and entrepreneurial early-stage researchers that will develop methodologies, tools and databases to guide the formulation of robust biologics. The consortium will not only provide a