RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Redesigning brain circuits in development' in the context of a Horizon 2020 call.

assistant: **Objectives**

In the pre-optogenetics era, molecular genetics defined the concepts of neural circuit development providing mechanistic insights into axon guidance and synapse assembly. However, this approach often revealed limited insights into the function of the circuits studied. Since 2005, optogenetics has revolutionized our approach to functionally dissect brain circuits and has tremendously increased our understanding of how they contribute to specific behaviours. However, how these circuits assemble during development remains mostly unknown. Here, I propose to combine these two approaches: to genetically redesign specific circuits during mouse development in a predictable fashion, and to test the consequences for innate and learned behaviour. This novel line of research follows concepts of synthetic biology, which aims at reconstructing cellular systems, with the intention of redesigning brain circuits to reroute information processing for new behavioural purposes. We aim to demonstrate that targeted mis-expression of connectivity signals can alter specific neural circuits and communications between circuit components along measurable hypotheses. Activation of such an artificial circuit, by either natural stimuli or optogenetics, is likely to produce a set of behavioural outcomes that will reveal general connectivity rules, the capacity for behavioural plasticity, and possible functional redundancies between circuits. Anatomical and physiological dissection of the redesigned circuit will reveal to what extent the incoming afferents instruct the target cells to produce their output responses. Our focus will be on the amygdala, a forebrain structure necessary for processing aversive and rewarding stimuli and orchestrating behavioural responses, and a brain circuit characterized
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Realised ecological niche and species distributions under global environmental change' (RELOAD), addressing dissemination and exploitation.

assistant: **Impact**

Species are readjusting their geographical distributions as a response to ongoing environmental change. Thus, predicting species distributions is an urgent conservation endeavour. However, the responses of a species to the environment may vary in space and time (i.e. niche change) as the result of the spatiotemporal context of where and when its different populations occur. Niche changes are expected to have important consequences: (i) they can invalidate niche-based species distribution models, as a widely used predictive conservation tool, due to the limited spatiotemporal context of the underlying species distribution data, and (ii) they can impact the performance of species (e.g. their conservation status and extinction risk) that become decoupled from their optimal environmental conditions. However, we still poorly understand how the magnitude of niche change varies among species, especially within their native distributions and over relatively short time spans under ongoing global change. I will study how and why the magnitude of niche change varies among bird species. More specifically, I will examine how species functional traits and rates of global change within the species' geographical ranges affect the magnitude of niche change, and how niche change may impact the conservation status of species. The ultimate goal is to produce a global synthesis of spatial and temporal niche change to understand the general propensity of bird species to change their realised ecological niches. The project will contribute to estimate species-wise uncertainty of species distribution models and refine their predictions based on species' ecological traits.


**Keywords:** niche, species distributions, global change, traits, birds
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The contribution of the actin cytoskeleton and a potential rho-gtpase to theroot-hair deformation during rhizobium infection' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

Research objectives and content The symbiotic interaction of the bacterium Rhizobium with the root nodules of leguminous plants i crucial for nitrogen fixation. It has been shown that Nod-factors secreted by the bacteria are important for signaling the plant cells to initiate the early steps of nodulation. One of these steps is the deformation a root hairs. This morphological change is the result of re-establishing polar growth and is driven by changes in the actin cytoskeleton. In other systems, rho proteins play an important role in polar growth and in mechanisms controlling actin cytoskeleton configuration. The recent identification of a rho family protein in these plants in T. Bisseling's group suggests that this GTPase may regulate the actin cytoskeleton in this system. The aim of my proposal is to study the actin cytoskeleton in living root hair using actin-GFP constructs and the potential regulation of the actin configuration by the novel rho-protein in more detail. This project has two experimental goals. First, to visualize the actin cytoskeleton in living root hairs. Second, to overexpress the wild type and different mutants of the rho-protein and to correlate these conditions with a morphological and biochemical characterization of the actin cytoskeleton in root hairs. Training content (objective, benefit and expected impact) In Ton Bisseling's group I have the opportunity to learn a completely new subject (plant cell biology) as well as molecular biological methods. This project may give insights which are of general importance for signal: tansduction in plants. Links with industry / industrial relevance (22) Nitrogen fixation is a crucial process for Agriculture throughout the world.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Taraxacum officinale as a new plant-herbivore model to study fitness benefits of root secondary metabolites' (Dandelion), addressing dissemination and exploitation.

assistant: **Impact**

Plants invest much energy into synthesizing root secondary metabolites which are assumed to improve plant fitness by protecting the plant against below ground herbivores. Testing this paradigm however has remained difficult due to the lack of suitable model plants. The key objective of this proposal is the establishment of the common dandelion (Taraxacum officinale) as a powerful native chemo-molecular root-herbivore model to study the function and adaptive value of root secondary metabolites in nature. The proposed activities will not only expand the current understanding on plant-environment interactions, but will also deliver essential resources for further research on an ecologically and economically relevant plant species native to central Europe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Tracking the Intestinal Permeation and Circulation Effects of Environmental MicroPlastics'.

assistant: **Objectives**

Plastic pollution poses a significant threat to human health, particularly through the infiltration of microplastics (MPs) into the body. Emerging studies have detected MPs in various organs, with food and drinking water identified as major sources of exposure. While clinical studies suggest potential links between MPs and conditions such as thrombosis, liver cirrhosis, and endometriosis, a critical gap remains in understanding how the physicochemical properties of MPs, altered by environmental weathering, influence their ability to permeate biological barriers like the intestinal lining—a key gateway to systemic exposure.The TRACE-MP project (Tracking the Penetration and Circulation Effects of Environmental MicroPlastics) addresses this gap by investigating how environmentally relevant MPs, specifically those prepared by artificial weathering and with bio-coronas (BC) formed through interactions with proteins and lipids in the gastrointestinal tract and blood, permeate the intestinal barrier and induce vascular endothelial leakiness. This research will utilise advanced in vitro models, including static and dynamic systems, to simulate realistic biological conditions. The project’s objectives include: (1) characterising bio-coronas on MPs in the gastrointestinal and blood environments, (2) evaluating the permeation of MPs-BC complexes through the intestinal barrier, (3) assessing their potential to induce endothelial leakiness, and (4) correlating these findings with the physicochemical properties of MPs to perform a comprehensive risk assessment.By advancing our understanding of the mechanisms underlying MPs' systemic distribution and impact on human health, TRACE-MP will inform regulatory policies and mitigation strategies to protect public health from plastic polluti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Multiple-Access Quantum Key Distribution Networks' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

I propose the theoretical study of multiple-access quantum key distribution (QKD) networks. Quantum cryptography is an emerging interdisciplinary field of science and engineering with developing commercial applications. It is one of the objectives of the work programme to provide European citizens with the security level that the quantum technology offers. Multiple-access QKD networks make us one step closer to this goal, and open up new marketing opportunities by introducing more flexible configurations as compared to the current point-to-point QKD links. In a multiple-access network, every two users can use a shared channel to exchange a secure key without trusting any other users. This shared channel can be used, possibly, at the same time, by other pairs of users who also wish to create secure keys. Such an advantage becomes possible by employing the well developed multiple-access techniques in classical optical communication networks. In particular, I intend to study the three schemes of wavelength, code, and time division multiple access, in which, respectively, each user is assigned a particular wavelength, code, or time slot. The main question to answer is how the interference caused by other users will affect the rate of secure key generation in a multiple-access QKD setup. It is also important to compare different network configurations in terms of their architecture and cost. Finally, I would like to investigate the possibility of extending the ideas relevant to local and metropolitan area networks, to wide area networks, where we need to employ quantum repeaters for the secure exchange of the key. Experimental demonstration of such networks will also be pursued via finding other sources of funding or in collaboration with other research groups.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Mortal Medicine: The Social Life of a Death-Inducing Pharmaceutical' in the context of a Horizon Europe call.

assistant: **Objectives**

MORTALMED is an anthropological project that investigates the global movements and local uses of sodium pentobarbital (SP) as a pharmaceutical that is employed primarily to facilitate both voluntary and coerced death. Using a mixed-methods approach, MORTALMED reassembles the social life of SP, focusing on how its life-cycle intersects with historically and culturally situated forms of governance and emerging necro-socialities—spaces of sociality where death is actively managed, governed, and produced. The project traces SP’s circulation across three key contexts: (1) assisted dying in Switzerland, (2) state-sanctioned executions in the United States, and (3) its over-the-counter commercialisation in Mexico. These practices reveal how pharmaceuticals intersect with legal, medical, and political systems, governing life and death unevenly across varied socio-political landscapes. By focusing on SP as a pharmakon—both remedy and poison—the project uncovers how pharmaceuticals function beyond health contexts, exposing the broader socio-political dynamics and power structures that both shape and are shaped by their use. MORTALMED seeks to unveil how SP’s movement through formal and informal networks reflects and reinforces socio-economic and racial inequalities. By reassembling SP’s socio-cultural biography, the project offers a critical perspective on how pharmaceuticals contribute to the governance of life and death, providing insights into the contemporary and future implications of pharmaceutical-mediated death.


**Keywords:** Anthropology of Pharmaceuticals; Assisted Dying; Death Penalty; Ethnography; Governance; Necro-sociality
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'FACE Entrepreneurship. Failure Aversion Change in Europe, more than a Communication Campaing to create a new generation of  European entrepreneurs that can FACE failure and learn from it.' (FACE) under Horizon 2020.

assistant: **Objectives**

There is a need to change the European perception of failure, to change entrepreneurs’ attitude of fear and to replace it with an attitude of risk-taking, in order to improve entrepreneurship in EuropeFACE aims to promote entrepreneurship and diminish the fear of failure, it invites the public to take the path of entrepreneurship through the use of gamification methods. We encourage aspiring entrepreneurs and all those who are embarking on the journey together with us to take the path in an interactive, proactive and innovative way, thus diminishing the fear of entrepreneurship. To this end, we will: 1. Turn to a group of experts from the entrepreneurship ecosystem, in order to define the project’s content and offer guidance2. Create a game with 63 squares that reflect the different stages of entrepreneurship.  A web series provides the narrative thread that runs through the game; it will be fun and get people hooked. Entrepreneurs, investors, ...offer their opinions on the storyline, on the success stories and lessons learnt, while everyone can participate and win points towards their final score3. Organise 7 events in 7 European countries, every time a square representing a setback or failure is reached - at this critical time we need to get together and “FACE it”. The events will be dynamic and participatory.Those entrepreneurs with the highest scores will get their prize at the event4. Launch an important communication action in order to make a great impact in Europe, via social netnetworks, the media and different partners who work together with us, including Wayra (Telefonica) and Microsoft who offer their full support: infrastructures across Europe, specific actions, expertise in entrepreneurship and disseminationWe will involve the public while having an impact
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Archaeology of Commons: cultural Heritage and Material Evidence of a Disappearing Europe' to be submitted under Seventh Framework.

assistant: **Abstract**

The main goal of the project is to attain the intimate social dimension at the base of the common lands management in the context of South Europe Mountain regions, by means of historical and archaeological analysis.The existence of common lands, the complexity of their different uses and the permanence of common rights on lands were crucial in shaping rural landscapes, so they are nowadays protected as natural heritage (Natural parks, Sites of Communitarian Interest). However, the historical organization of common lands is not well known.The main question of the project is how archaeological methods can investigate the dynamic nature of commons. In order to answer this question and combining landscape archaeology and documentary research methods, the fellow Dr. Anna Maria Stagno will investigate two paths:- reconstructing topographical organization of common lands and its transformations- archaeological visibility of conflictsThe project will be developed in two areas in Basque Mountains (Sierra Cantabrica and Alarar Mountains). Through the employment of different archaeological methods, the project plans to link the study of primary production areas and settlements, considering all together the investigation of private lands, common lands historically used by the same community (and to identify the different communities/settlements that, through the ages, have held common access rights on the same areas) and settlements.The project covers a trans-European dimension based on the enhancement of the existing dialogue between three research groups that investigate rural areas (GIPyPAC of University of Basque Country, FRAMESPA of the Toulouse Le Mirail University and LASA of Genova University). The results of the Spanish case studies will be compared, trough targeted invest
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The kappel ship propulsion concept, improving energy efficiency and reducing the environmental impact' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

Merchant ships are large consumers of fossil fuels, which means that the operators' energy costs are high and that impact of emissions on atmospheric pollution is significant in coastal areas. One of the ways to improve the utilisation of energy is to improve the efficiency of the ship's propeller. Certainly, the conventional propeller has for practical purposes reached the upper efficiency limit of its development and it is therefore necessary to look to innovative means of achieving significant improvements in this area. One of such means is the application of non planar wing theory to propeller design. This theory was originally investigated and developed for use in the aviation industry and a number of commercial airliners now feature non planar wings in the form of winglets at the wing tips giving increased performance from the airfoil wing resulting in improved fuel consumption and a greater operating range. There is a history of technology transfer from the aviation industry to the marine industry.The unique feature of the KAPPEL propeller is that the theory of non planar wings and winglets has been transformed to marine propellers and applied to a propeller concept where the propeller blade and winglet" are designed as one integral curved blade to reduce the energy losses inevitably present at the ends or tips of airfoil devices. Hydrodynamic design and analysis procedures have been formulated and are being refined by KAPPEL Marine Concept in association with the Technical University of Denmark. The mathematical and physical modelling carried out to date indicate that it is realistic to expect fuel savings of up to 7% compared with a well designed conventional propeller. In the case of a medium sized container vessel of the type to be investigated in this propos