RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Mechanisms of cerebral preconditioning' (CERPREC) targeting Sixth Framework.

assistant: **Abstract**

Despite increasing knowledge about stroke, treatment options remain unsatisfactory. Because the transfer of neuroprotective agents from the animal model to the patient has turned out to be problematic, there is tremendous interest in new ways of neuroprotection that might be feasible in humans also, such as the induction of endogenous cerebral protection. These mechanisms have been shown to be inducible by a sublethal toxic stimulus in vitro and in animal models (preconditioning", "Ischemic tolerance"). In a recent study on stroke patients with antecedent transient ischemic attacks, the applicant found evidence for the existence of ischemic tolerance in the human brain.The proposed project will address the following questions:1) What factors elicited by preconditioning cause ischemic protection?2) Is there a specific tissue ¿signature¿ of preconditioned tissue?3) What distinguishes preconditioned tissue in a following ischemia from first ever ischemic brains?Magnetic Resonance Imaging (MRI) will be applied to a rat model of hypoxic preconditioning and focal ischemia, to assess parameters of cerebral perfusion and tissue integrity and their spatial and temporal relation to the development of tolerance. To identify a vascular component of preconditioning, MRI at 7 Tesla will include highly sophisticated arterial spin labelling techniques for perfusion-weighted imaging, developed at the host institution. Co-registered histological data will provide information on the extent and character of ischemia-induced neuro genesis.This comprehensive approach will allow addressing our principal hypothesis: induction of ischemic tolerance is facilitated by a concerted process of protective mechanisms on cellular and vascular level, rather than by independent single events. The transfe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Regenerative Medicine Innovation Crossing - Research and Innovation Staff Exchange in Regenerative Medicine' (REMIX) under Horizon 2020.

assistant: **Objectives**

Natural materials in biomedical field are investigated for clinical use, as materials for the fabrication of biomedical prostheses, for the stimulation of regenerative medicine patterns, or as carriers for drug release, and have acquired increasing relevance in the past years, being recognized their intrinsic bioactive properties and the possibility to repair and overcome diseases with the use of Tissue Engineering and Regenerative Medicine (TERM) based procedures.Different kinds of natural materials like silks from silkworms, chitins and chitosan from crustacean, corals, collagen from marine organisms, polymers derived from plants or algae have found or are investigated for clinical use.Research activities will be directed to the exploitation and validation of natural materials for tissue engineering applications.The exchange of faculties and researchers aims also at comparing methods, regulations, procedures, good practices and methodologies with the goal of establishing a consensus on the use of in vitro experiments for the validation of materials, the possibility of building in vitro models for the investigation and the reduction of animal testing, and the use of in vitro technologies for the construction of 3D predictive models to be used for the evaluation of biocompatibility of materials, efficacy of regenerative process and drugs efficiency without earlier use of animal testings, and to model disease progress and mechanisms (e.g. tumor models).The involved institutions have a proven excellence in the area covered by this proposal, and scientific collaborations already exist among their scientists. Besides, the two EU partners are members of the European Institute on Regenerative Medicine, with a dense network of collaborations all over the world.The exchange of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Gauge-yukawa unification' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

As a natural extension of the Grand Unified Theories (GUTs), we have proposed the idea of Gauge-Yukawa Unification (GYU). The GYU is a functional relation among the gauge and Yukawa couplings provided by some principle. In our studies the GYU has been achieved by demanding the principles of reduction of couplings and finiteness. The first principle is based on the existence of renormalization group invariant (RGI) relations among couplings which preserve perturbative renormalizability in gauge theories. The second principle is based on the fact that it is possible to find RGI relations among couplings that keep finiteness in perturbation theory, even to all orders. We have examined the application of these principles in various models as well as the resulting predictions. in particular those connected with the masses of the top and bottom quarks. It is proposed to continue our research program in the above framework and to attempt to extend it. More specifically, we propose to : (i) Continue the studies in other supersymmetric GUTs, (ii) Refine the predictions by including a soft supersymmetry breaking sector and threshold effects, (iii) Extend the study in attempts to understand the light fermion masses and mixing angles, (iv) Reexamine the hierarchy problem of GUTs in the present framework, (v) Attempt to find links of the present scheme with superstrings as well as with other higher dimensional theories.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'TEst of Tilt-Rotor Air intakes'.

assistant: **Concept**

The project pertains to the wind tunnel testing of the engine air-intakes of a tilt-rotor aircraft. The testing activity aims to evaluate the effectiveness of the internal intake duct shape optimisation performed by GRC. Both the original and the optimised duct geometries will be tested in a purposely designed and manufactured nacelle model which includes the rotor hub and the external part of the wing.Detailed measurements of the duct internal flow will be carried out, including bench tests with an internal PIV survey that will increase the insight in the physical flow behaviour.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Boosting Best Available Techniques in the Mediterranean Partner Countries' (BAT4MED), addressing dissemination and exploitation.

assistant: **Impact**

BAT4MED is a 33-month project, whose main objective is to ensure a higher level of environmental protection of the Mediterranean region, minimising the negative impacts associated to the activity key industrial sectors.To that aim, the possibilities for and impact of diffusion of the EU Integrated Pollution Prevention and Control approach to the Mediterranean Partner Countries (MPC) will be assessed and the implementation of Best Available Techniques in the national environmental  programmes will be promoted and supported. BAT4MED aims to help implement the EU Technologies Action Plan by supporting the transfer and uptake of environmental technologies in developing countries. Industrial pollution processes account for a considerable share of the overall pollution in the Mediterranean region. Though awareness of environmental issues related to industrial pollution has notably grown in the last decades, pollution monitoring shows that the positive results have hardly been achieved. The goal of the project justifies its transnational dimension, since pollution in the Mediterranean has a global dimension and cannot be tackled separately by each single country.The project brings together 8 organisations from 6 different countries,4 organisations from 3 EU Member States (Spain,Belgium,Italy),3 from 3 MPC (Egypt,Tunisia,Morocco) and 1 international organisation based in Egypt to build mutual understanding through established networking in industrial pollution prevention and control. Firstly, BAT4MED will analyse the industrial context in the MPC to select the most promising sectors with the highest environmental benefit potential.Secondly, a methodology for BAT assessment will be designed and applied and BAT will be selected for each identified sector taking into account local
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Helping Children to Make the Best of their Transition to High School' to be submitted under Horizon 2020.

assistant: **Abstract**

Poor social experiences with peers, such as peer rejection or peer victimization, and with teachers, such as receiving low support or having conflictual relations with teachers during elementary school impede children’s self- and stress-regulation. The affected self- and stress-regulation places these children at risk of developing similar troublesome relations with teachers and peers after the transition to high school. We propose to develop a serious game named A.L.I.B.I. to help children make a successful transition from elementary school to high school. In A.L.I.B.I. children play in a virtual high school environment. The objective of A.L.I.B.I. is to uncover an alien, who is disguised as a teacher or peer. By engaging in prosocial interactions with teachers and peers, by taking the perspective of others, by learning to overthink multiple response options before acting, and by valuing long term perspectives over short term goals, children will receive clues that will help them to uncover the alien. The advantage of A.L.I.B.I. is that through the use of a virtual school environment, it provides children a realistic yet safe environment to learn and rehearse prosocial behaviors, to prepare them for the new social environment. In addition, A.L.I.B.I. is intuitively attractive for children, through its use of game elements and presentation on a tablet computer. The proposed ERC PoC grant has the goal to (1) develop A.L.I.B.I. into a stand-alone serious game that will be ready for implementation, (2) to test the effectiveness of A.L.I.B.I., (3) to integrate A.L.I.B.I. in ongoing school transition trainings as provided by three school counseling organizations in three regions in The Netherlands, and (4) to develop a marketing strategy for broader Dutch and European implem
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The Silence of States in International Law' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

International law is the law between States. It is identified by observing the behaviour of States and deriving rules from their behaviour. But, what happens when States do nothing? Can States be bound by their own silence? Can international law develop through the silence of States? Can States be responsible for doing nothing? What happens when States do not appear before international courts and tribunals? These questions are immensely significant for States, international courts and tribunals, domestic courts, and individuals, who are all interested in knowing what the obligations of States are and how they can be enforced within and outside international courts and tribunals. Yet, there are major gaps in our understanding of the meaning of State silence and its legal effects. This project is the first comprehensive study of the silence of States in international law. It will explore and analyze whether the silence of States can bind them, and if so, under which circumstances; the role of State inaction for the responsibility of States; and the effect of State inaction in the field of international dispute settlement, focusing particularly on the proceedings before international courts and tribunals. It aims (a) to make a major contribution to knowledge on the meaning of silence by providing a comprehensive taxonomy of the ‘silences’ of States and on the legal effects of different ‘silences’; and (b) to critically analyse whether a change in the law may be called for. The project will conduct research in wide-ranging and geographically representative State practice available in the six official languages of the United Nations, international jurisprudence and literature. It will also employ empirical analysis of the reasoning of government officials’ and international
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Evaluation of respiratory vaccines for children in South East Asia. Streptococcus pneumoniae (and Hib) conjugate vaccincs in prevention of childhood pneumonia in developing countries' (ARIVAC).

assistant: **Innovation**

* To consolidate work of the already established vaccine evaluation centre in the Philippines, i.e. the Research Institute for Tropical Medicine (RITM), Manila and to develop a new vaccine evaluation center in Vietnam as collaboration between the Pediatric Hospital No 1 (PHN1) and its counterpart (RH), Copenhagen.* To obtain baseline epidemiologic information from the two centres on natural acquisition of pneumococcal (Pnc) and Haemophilus influenzae type b (Hib) antibodies and of Pnc and Hib in the etiology of ARI in children <5 years of age.* To monitor the safety and determine the immunogenicity of candidate vaccines (Pnc and Hib conjugate vaccines) in infants in the SEA region.Expected Outcome* There will be two experienced vaccine evaluation centers in South-East Asia.* Safety and immunogenicity of pneumococcal conjugate vaccine established.* Safety and immunogenicity of Hib conjugate vaccine established in Vietnam.* Basal data needed for the planning of Pnc and Hib vaccination programs and efficacy trial will be available from two areas in the South-East Asian region.* Collect baseline antibody and carriage data of Pnc and Hib in the Philippines and Vietnam.* Determine the role and types of Pnc and Hib in hospital treated pneumonia in children less than 5 years of age (Philippines, Vietnam).* Vaccination by public health personnel in local health centers within EPI schedule. Vaccine safety measured by structured parental monitoring and home visits by a nurse.* A venous blood sample is obtained when the child enters the study at specified time points after vaccination. All antibody analyses will be done at KTL.* Safety and immunogenicity of the Hib conjugate in infancy in Vietnam will be studied as above. The data will also provide baseline information referred to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Advanced Programming Environments for Exascale Data-Centric Computing' under Horizon 2020.

assistant: **Concept**

Power efficiency has emerged as the primary design constraint for the next generation of computing systems and the dominant source of energy consumption has shifted from computing elements to the movement of data. This shift will make locality of data the new programming challenge of the decade. However, current programming environments take a compute-centric approach and do not reflect the realities of the architectural trends.  For performance and energy efficiency reasons, there is a critical need for a new data-centric programming paradigm that takes data locality as a primary criterion. Moreover the next generation of high performance systems (Exascale Systems) will be equipped with 2048-core chips, requiring applications to expose over a thousand-way concurrency. For a smooth transition to these advanced technologies, this project proposes a theoretical foundation and programming abstractions; embodied in an API (Application Programming Interface) that provides a rich interface to address the dual challenges of data locality and increased on-chip parallelism for emerging parallel computing systems. The ultimate goal of the project is to integrate the proposed API into real-life applications that are of great interest to Europe. The project will study Turbulent Combustion as a motivating application class because of its importance in energy production. The proposed research, by reinventing the programming environment to better reflect the realities of future platforms, will facilitate the transition to Exascale of applications that are critical for strengthening European leadership in HPC.


**Keywords:** High Performance Computing, Exascale Computing, Parallel Programming Models, Parallel Languages and Libraries, Compilers, Computational Fluid Dynamics, Turbulent
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Thermometric and radiometric measurements of sea surface temperature and their application to a neural network - based parametrisation of the bulk -skin temperature difference' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Research objectives and content Both components of this proposal, experimental and modelling, have been developed for my PhD. A fully working instrument which can be deployed in inner waters has been proven, as well as the feasibility of using a basic artificial neural network to model the bulk - skin temperature difference. Further work in these areas are required to lead to a better understanding of the complex processes that occur at the sea surface. This proposal outlines a study of the sea surface microlayer using thermometric and radiometric techniques to determine sea surface temperature. Profiling of this region of the sea is rarely undertaken due to the lack of instrumentation available whereas remote, infra-red devices are deployed on an operational basis by researchers involved in this area of study. A comparison of the two methods of measuring sea surface temperature would provide a greater understanding of the processes affecting the behaviour of the microlayer. The data from cruises on board NERSC's research vessel as well as from other sources (e.g. CASOTS data-base) would be assimilated into a neural network model towards an improvement in the parameterization of the skin-bulk temperature difference which would prove to be invaluable when interpreting bulk sea temperatures from satellite-derived SSTs. Training content (objective, benefit and expected impact) Utilisation of NERSC's facilities and expertise will be made which include extensive computing power, infrastructure for instrumentation development, the availability of ship time, and the experienced staff of scientists not available in Ireland. The results would be applicable to other EC-funded projects involved in air-sea interaction including ASGAMAGE, CASOTS, COASTWATCH '95, etc. The possibility
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Electronic Structure of Chemical, Biochemical, and Biophysical Systems: Multiscale Approach with Electron Correlation'.

assistant: **Concept**

The currently available computational methods have often serious limitations to treat systems where electron correlation plays and important role. Many issues concerning the electronic structure of radicals, photoreceptors near-half-filled transition metals (Cr,Mo,Fe,Ni) are of paramount relevance in basic and applied research in Chemistry and Biochemistry, but still out of the capabilities of standard and conventional tools such as Density Functional Theory. On the other hand, post Hartree-Fock methods computationally more expensive and their application is limited to few atoms. The objective of the present proposal is to overcome these limitations and to develop and apply a multiscale, innovative and unconventional computer simulation technique to unravel the electronic properties of strongly correlated chemical and biochemical systems. The methodology is based on a combined approach between Quantum Monte Carlo (QMC), DFT and Molecular Mechanics. The proposed approach has a faster scaling of the calculation time with the system size N with respect others standard quantum chemistry methods of equivalent level (~ N4 vs ~ N7). es to address challenging open problems in the chemistry and biochemistry of radical compounds, photoreceptors, and transition metal catalysis and enzymatic activity. Application to photoreceptors include the study of the spectral properties of rhodopsin, the integral membrane protein responsible of the light detection in the retina. Applications on transition metal molecules will shed the light on the catalytic strategies of iron-based enzymes and their corresponding biomimetic compounds.