RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Control of gene expression in developing diencephalon by the transcription factor Pax6' (PAXBRAIN).

assistant: **Innovation**

Forebrain development is an extremely complex process that depends on the coordination of multiple molecular networks controlled by a relatively small group of transcription factors. Understanding of these genes, their downstream pathways and their spatial and temporal interactions is still far from clear, seriously limiting our knowledge of the molecular mechanisms of brain development and the causes of neurodevelopmental diseases. Our research will be aimed at deepening understanding of the molecular actions of one of such transcription factor, Pax6, during mouse diencephalic development with special attention to its interaction with the Shh pathway. We shall be following changes in gene expression profiles (by RNA-seq) in normal and Pax6 mutant cells (with or without Shh blockade treatment) and interrogating the data with bioinformatic methods. The outcomes expected from this aspect include identification of genes downstream of Pax6, the relationships between these genes and their putative interactions with the Shh pathway. In a second phase of the project, we shall test specific hypotheses on whether Pax6 regulates genes in the downstream networks through direct interactions (using ChIP and EMSA assays) and will correlate Pax6’s molecular actions with its cellular functions. This represents the first study of the diencephalon under this innovative and multidisciplinary approach.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'AI-ASsisted cybersecurity platform empowering SMEs to defend against adversarial AI attacks' (AIAS), addressing dissemination and exploitation.

assistant: **Impact**

In recent years, the digital environment and digital transformation of enterprises of all sizes have made AI-based solutions vital to mission-critical. AI-based systems are used in every technical field, including smart cities, self-driving cars, autonomous ships, 5G/6G, and next-generation intrusion detection systems. The industry's significant exploitation of AI systems exposes early adopters to undiscovered vulnerabilities such as data corruption, model theft, and adversarial samples because of their lack of tactical and strategic capabilities to defend, identify, and respond to attacks on their AI-based systems. Adversaries have created a new attack surface to exploit AI-system vulnerabilities, targeting Machine Learning (ML) and Deep Learning (DL) systems to impair their functionality and performance. Adversarial AI is a new threat that might have serious effects in crucial areas like finance and healthcare, where AI is widely used. AIAS project aims to perform in-depth research on adversarial AI to design and develop an innovative AI-based security platform for the protection of AI systems and AI-based operations of organisations, relying on Adversarial AI defence methods (e.g., adversarial training, adversarial AI attack detection), deception mechanisms (e.g., high-interaction honeypots, digital twins, virtual personas) as well as on explainable AI solutions (XAI) that empower security teams to materialise the concept of “AI for Cybersecurity” (i.e., AI/ML-based tools to enhance the detection performance, defence and respond to attacks) and “Cybersecurity for AI” (i.e., protection of AI systems against adversarial AI attacks).


**Keywords:** Cybersecurity, Artificial Intelligence, Adversarial AI, Digital Twins, Data Analytics, Cyberattack Detection
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Enhancing Innovation Management Assessment Capacity of Enterprise Europe Network partners and Innovation Management Capacity of SMEs' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Small and Medium Sized Enterprises (SMEs) face significant challenges to successfully innovate for sustainable growth. The Enterprise Europe Network (EEN) as a key player in the innovation eco-system is expected to render highly effective innovation management support services to SMEs. SMEs will adopt these innovation management support services to the degree that EEN staff members are well trained in innovation management support. This requires access to, and experience in assessing the SME’s innovation management capabilities in line with the technical standard CEN/TS 16555. Based on the assessment results, tailored action plans are to be developed and implemented in and with the SMEs. A solid understanding of both key success factors in innovation management is essential, and of effectively supporting SMEs of different age, size, industry, country in developing their innovation management capabilities for sustainable growth. Therefore, the EEENIMAC project aims at enabling the EEN to deliver consistently high value innovation management support services and to develop the performance in the regional innovation eco-system. To achieve these objectives, EEN eligible staff members will receive training, coaching, and on-demand support in state-of-the-art innovation management practices for different levels of proficiency. Furthermore, they will gain access to the proven IMP³rove online tools for assessing up to 4,500 SMEs’ innovation management performance in line with CEN TS 16555. In 4 work packages, a tailored, agile and impact-oriented skill development programme for 450 trainees p.a. will be combined with secure access to proven IMP³rove online assessment tools and international benchmarking databases. The training, coaching and on-demand support will be tailored to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'BAMBOO FOR EUROPE'.

assistant: **Concept**

Bamboo is a plant with remarkable properties and plays an important role in the daily life of about 2,2 billion people mainly in Asia.Bamboos are endemic in all parts of the world except in Europe where they did not survive the last glacial period. It is estimated that 1200 species are spread over the world. The total area represents about 18 millions of hectares with 3 millions in China and 8 millions in India.The interest in bamboo has increased wo rldwide and several international meetings are annually organised since 1980. Since the first introduction of bamboo in Europe (1827), about 400 different genotypes have been imported. With suitable management procedures, bamboo can produce an avarage of 10-15 tons/Ha. dry biomass annually. In the USA, extensive trials have been implemented allowing the study of important aspects such as mechanical harvesting. For the present proposal, a group of 13 species have been selected for planting experiments throughout Europe: Plant propagation, ecophysiological research, harvesting, preservation and storage problems will be studied under several tasks. Plant quality will be a central preocupation. Among the 2000 references existing on Bamboo, the large majority are coming from China and India where bamboo is developed as a source of biomass for Industrial Transformations. Nevertheless, Europe today has a technological advance in some areas such as the micro-propagation, the selection of superior genotypes using molecular markers and the biomass gazeification for energy production.This technological advance has to be integrated with the USA researches and with the Asian milenar experience.Any extensive bamboo production implies an industrial use. The present proposal aims to develop bamboo industrialisation into 3 steps.At short te
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'DATA SPACES FOR FLEXIBLE PRODUCTION LINES AND SUPPLY CHAINS FOR RESILIENT MANUFACTURING' (FLEX4RES) targeting Horizon Europe.

assistant: **Abstract**

Manufacturing industries continuously face the challenge of delivering high-quality products under high production rates while minimizing non value-adding activities. The recent COVID-19 pandemic is causing manufacturers to rethink and reassess their global supply chains and the flexibility of their production sites. Resilience means the ability to withstand difficult situations, while flexibility can be considered as the ability to accommodate changes without incurring significant extra costs. Production processes demanding high human skill such as forming processes, requires readjustment of the process parameters of all production steps as a new product evolves. The deficiencies can be attributed largely to the lack of efficient ways for trusted data sharing among the stakeholders without interoperability barriers. There is a need to be able to determine when such changes lead to deterministic-chaotic behavior with far reaching consequences.FLEX4RES provides an open platform to support production networks' reconfiguration for resilient manufacturing value chains. FLEX4RES will utilize platform-based manufacturing that builds on the state-of-the-art Gaia-X and IDS technologies for data-sharing in the horizontal supply chain and the Asset Administration Shell (AAS) that is to implement intra-factory reconfiguration practices. FLEX4RES considers the Digital Twin of the value-adding network a key enabling technology to achieve reconfiguration processes in highly flexible production systems and networks. The key element of technology linkage is represented by the Self-Descriptions with linked, standardized information models, especially in terms of resilience. The developed platform and specialized hardware aim to improve the existing industry-established lean management a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Functionalized AuNPs and their use for biological applications' (AuNP-PhotoBioDrug) targeting Horizon 2020.

assistant: **Abstract**

The development of gold nanostructures is a topic of high interest due to their extensive use in biomedical applications, biosensing and bioimaging because of their specific properties: high stability, ease of detection, facile synthesis and functionalization, etc. It would be of potential interest to predict the photobehaviour of AuNPs before introducing them in a biological environment. In this respect, when NPs interact in a living milieu, proteins will adsorb onto its surface generating a protein corona; this may provoke changes in the biological function of the protein and in the photophysical properties of the AuNP; thus, the photophysical behaviour of AuNPs in solution cannot be directly extrapolated to the biological media. These effects have been barely investigated up to now. The design of new gold nanoparticles whose photophysical behaviour can be extrapolated in a greater degree to a biological environment is of potential interest for in vivo applications due to the fact that their photobehaviour would be predictable within cells. Functionalization of AuNPs with nonsteroidal anti-inflammatory 2-arylpropionic drugs is proposed. These drugs are widely prescribed and are able to generate cytotoxic singlet oxygen, which induces cell tumour death. Their photophysical properties have been well characterised in solution. However, to the best of our knowledge, functionalization of AuNPs with drugs of this family has never been performed. The photophysical properties of the new nanomaterials will be studied in different microenvironments that tend to mimic cellular milieus, such as micellar or microemulsion media. Investigation of their photobehaviour in the presence of proteins is also planned. Finally, studies in an intracellular environment and in vivo will also b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Untangling the biophysical interactions governing biofilm hydraulic resistance using cyrogel membrane microfluidics' (MicroBioMem).

assistant: **Innovation**

Membrane biofouling is an inevitable factor severely effecting the permeate flux of ultrafiltration systems. This impacts the scalability of cheap, decentralised, low hydrostatic pressure methods such as Gravity driven membrane filtration (GDM). The hydraulic resistance of the biofouling layer is primarily controlled by biofilm, microbial communities embedded within a self-secreted extracellular polymeric matrix (EPS), a structure akin to a colloidal gel. Mesoscale experiments have shown biofilm hydraulic resistance to vary with hydrostatic pressure, however the microscale biophysical interactions inducing this behaviour are unclear. Understanding how hydrostatic pressure shapes EPS composition, spatial distribution and physical development of biofilm structures is crucial to establishing hydrodynamic strategies to reduce biofilm hydraulic resistance. With this proposal I will evaluate how EPS spatiotemporal distribution and local mechanical properties influence microscale fluid transport and the emergence of internal biofilm structures, to impact bulk biofilm hydraulic resistance, under a range of GDM hydrostatic pressures. To achieve this, I will develop a microfluidic platform embedded with a cryogel membrane barrier, enabling detailed monitoring of membrane bound biofilm development and hydraulic resistance under different hydrostatic pressures. Deploying a correlative imaging approach, I will quantify EPS regulation, composition and local mechanics using state of the art optical visualisation techniques paired with microrheological methods from soft matter physics. Evolution of fluid transport will be mapped using particle imaging velocimetry. Relationships between composition and hydraulic resistance established on the microscale will then be tested for scalabilit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'GEODE: GEographical Object Detection, Explained' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The GEODE project brings explainability to deep learning for Earth observation. GEODE aims at improving the transparency of computer vision models used for analyzing satellite imagery in large-scale mapping projects. As AI models are increasingly used in applications such as environmental monitoring and land-use classification, their opaque decision-making processes limit trust and usability. Using novel XAI (eXplainable AI) techniques, GEODE will offer pixel-level explanations to understand why a given model fails or succeeds on certain objects. Performance maps will indicate where the model is expected to have standard performance. Finally, an active learning strategy will be developed, to define how to conduct labeling work for global mapping.Answering the why, where and how deep mapping models work, GEODE is a bold step towards unlocking the full potential of AI paired with large volumes of satellite imagery. The project will take place at the Image & Signal Processing Laboratory at Universitat de València in Professor Gustau Camps-Valls'  group, a world-renowned leader in machine learning for Earth observation.


**Keywords:** Computer vision, explainable AI, Earth observation, large-scale mapping
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Local molecular profiling of tumor tissue sections: towards personalized immunotherapy' (BioProbe-PIT) targeting Horizon 2020.

assistant: **Abstract**

Cancer heterogeneity has reinforced the need for personalized treatment modalities. Pre-therapeutic diagnostic testing of heterogeneous tumors helps avoid inefficacious treatments, optimizes targeted therapy, and improves quality of life. Within targeted therapy, immunotherapy has led to significant improvements in treatment outcomes and is swiftly being integrated in diagnostic workflows.  In this context, routine diagnostic tests currently do not exist, and treatments are further challenged by heterogeneity. Spatially resolved molecular probing of tumors prior to treatment would allow prediction of patient response to immunotherapeutics.We have been developing methods to perform local biochemical reactions at micrometer length scales using nanoliter volumes of biochemicals. These methods are implemented using a scanning probe technology – the microfluidic probe (MFP) – with devices, platforms and assays adapted for application on biological substrates. With this, we are working towards multi-modal molecular profiling of tumors – tissue microprocessing (TMP).  Thus far, we have demonstrated TMP for local DNA and mRNA analysis on live cells, for patterning cells and for micro-immunohistochemical tests on tissues. Here, we will leverage TMP concepts to work on the initial steps in pre-commercializing the MFP for diagnostic testing in immunotherapy. Specifically, we aim to(1) develop assays for morphological and molecular analyses of pancreatic tissues using the MFP (2) adapt the assays developed in (1) to be compatible with workflows of state-of-the-art genome and transcriptome analysis for molecular profiling of tumors in diagnostics(3) validate these techniques for patient samples.With this PoC grant, we envision to translate the MFP technology from the lab to the clin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Edge AI Technologies for Optimised Performance Embedded Processing'.

assistant: **Innovation**

EdgeAI is as a key initiative for the European digital transition towards intelligent processing solutions at the edge.EdgeAI will develop new electronic components and systems, processing architectures, connectivity, software, algorithms, and middleware through the combination of microelectronics, AI, embedded systems, and edge computing. EdgeAI will ensure that Europe has the necessary tools, skills, and technologies to enable edge AI as a viable alternative deployment option to legacy centralised solutions, unlocking the potential of ubiquitous AI deployment, with the long-term objective of Europe taking the lead of Intelligent Edge. EdgeAI will contribute to the Green Deal twin transition with a systemic, cross-sectoral approach, and will deliver enhanced AI-based electronic components and systems, edge processing platforms, AI frameworks and middleware. It will develop methodologies to ease, advance and tailor the design of edge AI technologies by co-ordinating efforts across 48 of the brightest and best R&D organizations across Europe. It will demonstrate the applicability of the developed approaches across a variety of vertical solutions, considering security, trust, and energy efficiency demands inherent in each of these use cases.EdgeAI will significantly contribute to the grand societal challenge to increase the intelligent processing capabilities at the edge.


**Keywords:** Edge processing, Artificial Intelligence, hardware architectures, neuromorphic, middleware