RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Teaching Fuel Cell and Hydrogen Science and Engineering Across Europe within Horizon 2020' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

As the FCHT industry gradually emerges into the markets, the need for trained staff becomes more pressing. TeacHy2020 specifically addresses the supply of undergraduate and graduate education (BEng/BSc, MEng/MSc, PhD etc.) in fuel cell and hydrogen technologies (FCHT) across Europe.TeacHy 2020 will take a lead in building a repository of university grade educational material, and design and run an MSc course in FCHT, accessible to students from all parts of Europe. To achieve this, the project has assembled a core group of highly experienced institutions working with a network of associate partners (universities, vocational training bodies, industry, and networks). TeacHy2020 offers these partners access to its educational material and the use of the MSc course modules available on the TeacHy2020 site. Any university being able to offer 20% of the course content locally, can draw on the other 80% to be supplied by the project.This will allow any institution to participate in this European initiative with a minimised local investment. TeacHy2020 will be offering solutions to accreditation and quality control of courses, and support student and industry staff mobility by giving access to placements. Schemes of Continuous Professional Development (CPD) will be integrated into the project activities. We expect a considerable leverage effect which will specifically enable countries with a notable lack of expertise, not only in Eastern Europe, to quickly be able to form a national body of experts.TeacHy will offer educational material for the general public (e.g. MOOC’s), build a business model to continue operations post-project, and as such act as a single-stop shop and representative for all matters of European university and vocational training in FCHT. The project partne
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Realizing the semantic web' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

The current World Wide Web (WWW) is, by its function, the syntactic web where structure of the content has been presented while the content itself is inaccessible to computers. The next generation of the Web (the Semantic Web) aims to alleviate such problem and provide specific solutions targeted the concrete problems. The Web resources will be much easier and more readily accessible by both human and computers with the added semantic information in a machine-understandable and machine-processable fashion. It will have much higher impact on eWork and eCommerce as the current version of the web already had. Still, there is a long way to go transfer the semantic web from an academic adventure into a technology provided by software industry. Supporting this transition process of Ontology technology from Academia to Industry is the main and major goal of KnowledgeWeb.This main goal naturally translates into three main objectives given the nature of such a transformation.(1) Industry requires immediate support in tacking up this complex and new technology. Languages and interfaces need to be standardized to reduce the effort and provide scalability to solutions. Methods and use cases need to be provided to convince and to provide guidelines for how to work with this technology.(2) Important support to industry is provided by developing high-class education in the area of semantic web, web services, and Ontologies.(3) Research on Ontologies and the semantic web have not yet reached its goals. New areas such as the combination of semantic web with web services realizing intelligent web services require serious new research efforts.Spoken in a nutshell, it is the mission of Knowledge Web to strengthen the European software industry in one of the most important areas of current
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Dissecting the impact of epithelial stem cell niches on oral cancer heterogeneity' (OralNiche).

assistant: **Concept**

The oral epithelium is a unique tissue with a high degree of structural heterogeneity and distinct microenvironments (niches). However, the molecular mechanisms underlying the site-specific proliferation and differentiation of oral epithelial stem cells (OESCs) remain poorly understood. Oral squamous cell carcinoma (OSCC), one of the most common oral cancers, is a heterogeneous cancer type. Occurrences of metastatic lesions and treatment response differ from oral site to site, indicating a causal link to the heterogeneous nature of distinct OESC pools. In the OralNiche project, we will for the first time systematically and comprehensively characterise the OESC pools, dissect key mechanisms underlying oral epithelial site-specificity and define their contribution to OSCC heterogeneity. To achieve this, we will combine novel mouse models and patient material with cutting-edge methodology, including whole mount imaging, single-cell sequencing and organoids.  Initially, we will profile the proliferative activities of OESCs and explore how stemness is regulated within defined niches in homeostasis, OSCC and chemotherapy-induced mucositis. Subsequently, we will functionally assess cellular cues that modulate stemness in the oral epithelia and generate a comprehensive single-cell atlas of OESCs and their cellular niches. Lastly, using OSCC patient material, we will validate key observations to define potential new biomarkers and therapeutic targets. In summary, this multidisciplinary approach will reveal how the distinct OESC pools maintain homeostasis, and how they respond to challenges, such as mucositis and OSCC. OralNiche will deliver new knowledge on the impact of tissue site-specificity on tumour heterogeneity and therapy response, which will have significant implication
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Smart and Sustainable Insular Electricity Grids Under Large-Scale Renewable Integration' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

A large share of the recent renewable energy sources (RES) installed capacity has already taken place in insular electricity grids, since these regions are preferable due to their high RES potential. However, the increasing share of RES in the generation mix of insular power systems presents a big challenge in the efficient management of the insular distribution networks, mainly due to the limited predictability and the high variability of renewable generation, features that make RES plants non-dispatchable, in conjunction with the relevant small size of these networks. The Smart Grid initiative, integrating advanced sensing technologies, intelligent control methods and bi-directional communications into the contemporary electricity grid, provides excellent opportunities for energy efficiency improvements and better integration of distributed generation, including RES such as wind and photovoltaic systems, coexisting with centralized generation units within an active network.SINGULAR investigates the effects of large-scale integration of renewables and demand-side management on the planning and operation of insular electricity grids, proposing efficient measures, solutions and tools towards the development of a sustainable and smart grid. Different network operation procedures and tools, based on innovative approaches of predictive electricity network operation, will be developed.A set of electricity network planning procedures and tools will also be developed to implement robust insular electricity network planning.The goal is the generation of effective solutions and information so that the integration of insular and highly variable energy resources is maximized. The operation and planning tools and procedures will be applied in different insular electricity grids in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'SERBian- Austrian-Italian (SAI) partnership FORcing EXCELLence in ecosystem research' (SAI) under Horizon 2020.

assistant: **Objectives**

The overall aim of the project is the upgrade of knowledge, skills and social capacity of UNSFA in the field of environmental sciences, with special focus on agrometeorology and related ecosystem sciences (such as plant physiology, crop management). The main tool for reaching that aim will be establishment of the AgMnet+ research network at UNSFA in collaboration with leading international research institutions BOKU and UNIFI. As a strategy to improve S&T capacities of UNSFA, AgMnet+  will introduce the concepts of small study groups (SSGs) of UNSFA, BOKU and UNIFI students and develop joint study teaching material in English and native languages. BOKU and UNIFI partners will implement goal-driven measurement and modelling training in the selected research fields for AgMnet+ members. Additionally, EU partners will organise expert training related to preparation of research project proposals for  AgMnet+ researchers. Intensive exchange of short term scientific visits, guest lectures and students visits among partner institutions will contribute to improved eligibility of AgMnet+  members for participation on EU projects, increased number of papers in peer-review journals and increased citation. Finally, AgMnet+ will serve as a robust basis for the further sustainable development of the selected research fields at UNSFA, in Serbia and wider region of Western Balkan Countries. Strategic partnership with BOKU and UNIFI, initiated by this project will significantly enhance the research and innovations capacities of UNSFA and help to upgrade the knowledge and skills of both of its students and researchers. Additionally, it will reduce potential ""crowding out"" effect at BOKU and UNIFI and increase  research and social capacity of all project participants.""


**Keywords:** A
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Re-designing the construction sector: Sustainable and functional bio-based construction products and building elements' to be submitted under Horizon Europe.

assistant: **Abstract**

The BIOS MATER aims to develop and demonstrate advanced bio-based construction products and building elements with tailored functional properties such as durability, fire resistance, water barriers, acoustic and thermal insulation, lightweight structure, mechanical strength, and antimicrobial features, ensuring safety and sustainability. At the core of the concept are the four Production routes which are built around four pillars. Specifically: Production route A will focus on the development of  bio-based  core product and sandwich structure for flooring applications, Production route B will focus on the development of bio-based wall panels and flooring tiles, Production route C will focus on the development of fiber reinforced bio-resin composite panels applied as exterior façade cladding panels and Production route D will focus on the development of biodegradable and plantable bio-based tiles from  foams applied as drywalls panels. Moreover, the four pillars are: Pillar 1. Innovation in bio-based construction and building product development; Pillar 2. Health, safety, and environmental impact through Safe and Sustainable by Design (SSbD), Pillar 3. Circular economy integration and scalability and Pillar: 4 Driving market adoption of bio-based products through digital transparency, stakeholder engagement, and social acceptability. Key elements include life cycle assessments (LCA), circularity, and SSbD assessments. BIOS MATER will test and demonstrate the compatibility of these products  with existing construction practices and regulatory frameworks at the controlled real-world application of a DEMOpark. The project also incorporates stakeholder engagement, training, and awareness programs, with 22 partners from 10 EU countries working together to achieve these goals
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'A multifaceted platform for exploring nucleotide-based post-translational modifications' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Nucleotide-based post-translational modifications (nbPTMs) play key roles in health and disease, from bacterial pathogenesis to cancer. However, technical challenges of these versatile, but chemically complex protein modifications have constrained our fundamental understanding of even the most intensely studied nbPTMs for decades. The overarching aim of this proposal is to establish, apply and disseminate a methodology to unveil novel types of nbPTMs and allow site-specific proteomic analyses. The conceptual innovation lies in a strategy for turning the complex chemical structures of nbPTMs from a challenge to an advantage. First, shared chemical moieties will be exploited to develop pan-specific enrichment of multiple nbPTMs. For this purpose, we will generate the first nbPTMs-specific antibodies by converting specific signalling proteins into biotechnology tools for chemoenzymatic synthesis of challenging peptide antigens (aim 1). Second, we will take advantage of the chemical lability of nbPTMs to analyse modified peptides using a nucleobase-targeted mass spectrometry approach (aim 2). The unbiased scope of our methodology will make possible the discovery of as yet unknown forms of nbPTMs (aim 3) and nbPTM site mapping throughout eukaryotic proteomes (aim 4). These new materials, methods, discoveries and datasets will be made publicly available to allow future investigations of nbPTMs by the scientific community. The new substrates, sites and nbPTMs will provide starting points for biological characterization (aim 5). Poised at the interface of biology and technology, this interdisciplinary research project has the potential to explore new territories within established biomedical fields and to contribute to the knowledge base for improved treatment of diseases.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Assessing Tourism Sustainability in the EU Region: A Quantitative Approach'.

assistant: **Concept**

The TOURSUS-EU proposal is designed to contribute to the definition of and the transition to a more sustainable model of tourism, which is one of the major issues of the EU. As a highly interdisciplinary project, TOURSUS-EU intends to introduce a new approach to measuring the impact of mass tourism on the economy and society, by analyzing data from important tourist destinations listed in the UNESCO World Heritage sites (Venice, Lisbon and Split). The proposal relies on the use of state-of-the-art knowledge and state-of-the-art analytical methods (Dynamic Panel Models, time series analysis, MultiCriteria Decision Analysis and Big Data Analysis) in order to develop an innovative structured approach for the assessment and improvement in tourism sustainability. In particular, the project will allow for the quantitative evaluation of the effects of various factors on the negative developments in tourism sector, as well as the assessment of the sustainable growth in tourism that will take into account the negative effects that mass tourism generates. The expected results will be beneficial for both the scientific and the local community and will have an impact on the formation of management practices within tourist destinations, potentially to be adopted in other regions and tourist destinations in Europe and worldwide. The realization of the project TOURSUS-EU will be a turning point in my career. Considering BRU Iscte is a recognized multidisciplinary research center with Researches Excellence, I firmly believe that the proposed cooperation and TOURSUS-EU will open up the best future career possibilities for me. It will significantly help me to increase my expertise in the application of new relevant techniques in the field of sustainable tourism, allowing me to grow as an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'HUman EXoskEleton for autonomous movement control'.

assistant: **Concept**

The objective of HUMEXE is to develop all the necessary stages to introduce in the market a new exoskeleton able to provide full autonomy to patients suffering from paraplegia and improving current exoeskeletons available on market or at research stage. This new exoskeleton follows an entirely different approach for the movements control strategy. HUMEXE, as contrast to the rest of exoskeletons, bases the movement control of the lower limbs on the movement of the upper limbs of the individual, thus providing the user the full control of his movements, instead of being a control unit in control of the movements and their trajectories. This new approach will allow the user to control the lower limbs’ movements without the aid of crutches or the supervision of another person, and these movements will be performed more accurately than competitors’, thanks to the increase of freedom degrees of the exoskeleton (13, in contrast of a maximum of 10 and an average of 4 in other competitors). Besides it will reduce dramatically the computing requirements of the control unit, resulting in a simpler device, fail-safer and cheaper, easing the access to the exoskeleton to the general public.This new exoskeleton has been developed by Tecnimusa, a leading company on providing innovative engineering solutions to their clients who can not find a satisfying one among the current solutions in the market. Tecnimusa is an engineering SME, based on Murcia (southeast of Spain) and founded in 2011. Its main line of business is the providing and development of solutions consisting on the combination of different technologies to perform accurately their objective.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Dobutamine for NEOnatal CIRCulatory failure defined by novel biomarkers' (NEO-CIRC).

assistant: **Innovation**

Dobutamine and adrenaline are widely used as second line therapy for systemic hypotension in infants. Dopamine is currently the most widely used first line drug. In neonates, sustained hypotension may, and impaired organ perfusion will, cause brain injury and poor neurodevelopmental outcomes. All three catecholamines are currently used off-label and have different modes of action which may result in potentially harmful haemodynamic effects. No reliable safety or efficacy data exists for the use of these drugs in neonates or newborns.  Furthermore, no uniform criteria exist to define hypotension and there is little evidence to support current intervention strategies, which vary widely.  Recently, superior vena cava (SVC) flow has been proposed as a more reliable indicator of circulatory failure than low blood pressure and preliminary results suggest Dobutamine is the optimum therapeutic in such cases. NEO-CIRC proposes 1) a randomised placebo controlled trial to provide safety and efficacy data for Dobutamine as a first line inotrope for all gestational ages 2) to perform pre-clinical; pharmacokinetic; pharmacodynamic; metabolomic and pharmacogenomic studies 3) to develop improved biomarkers of hypotension 4) to develop and adapt a formulation of Dobutamine suitable for newborns with the aim to apply for a Paediatric Use Marketing Authorisation. The NEO-CIRC consortium includes international experts in neonatal medicine, pharmacology, pharmacogenomics, drug formulation and pre-clinical neonatal models and an experienced group of experienced multicentre clinical trials NICU’s.  Outcomes anticipated include improved biomarkers of organ perfusion; a new consensus definition of neonatal circulatory failure and answers to key clinical practice uncertainties, including variabi