RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'A study on the interaction among natural selection, mutation and recombination, with Caenorhabditis elegans experimental evolution' to be submitted under Seventh Framework.

assistant: **Abstract**

The process of adaptation to novel environments is of extraordinary importance to understand the existence of biological diversity. The development of a theory of adaptation during the last 150 years identified natural selection as its cause, and the conditions under which it depends on the existence of the heritable variation encoded in DNA sequences, introduced in finite populations by mutation, recombination and migration. Despite the considerable knowledge about the mechanism of evolution, an understanding of genetic basis of adaptation remains both a theoretical and an empirical challenge. In this project we propose to conduct an unprecedented large scale evolution experiment with the androdioecious nematode Caenorhabditis elegans, under varying levels of outcrossing rates, initial standing genetic variation and frequency of environmental change. With the integration of information from several levels of structural organization, from fitness-proxy and life-history phenotypes to genome wide RNA expression, it will be possible to determine the several genetic and environmental components of diversity. Furthermore, we will perform whole genome linkage disequilibrium (LD) association mapping with experimental evolution, thus determining at the DNA sequence level how the genome is organized and how it feeds back into the population genetic dynamics. Tests of evolutionary theory will be conducted with the data collected. Directional natural selection is expected to maintain genotype diversity, when there are non-linear interactions among several loci. But predominantly stabilizing selection will erode this genetic diversity. While in the first scenario outcrossing will be favoured, in the second it will be a hindrance to adaptation. After an initial characterization, we
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Coeliac disease-monitoring & diagnosis using an integrated chip system' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

Coeliac disease (CD) is gluten induced naturopathic inflammatory disease of the upper small intestine. The prevalence of CD was beloved be 1 in 300, but recent evidence suggests there are more undiagnosethan diagnosed cases, with diagnosis being complicated by non-specific symptoms coupled with expensive and non-routine methods of diagnosis. This Project aims to develop a disposable integrated micro system com-posed of discrete biosensor modules that will:a) asses the susceptibility of an individual to CD by screening for the associated Labb) by exploit and-and enzyme sensor technology to provide screening tool for diagnosis of CD andc) facilitate monitoring of the disease in response to a gluten free diet. The discrete modules proposed can also be utilised as individual disposable units to enabled sufferers to self monitor their disease state in response to their diet.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Excitonic Magnetism in Strongly Correlated Materials' under Horizon 2020.

assistant: **Concept**

Spontaneous symmetry breaking leading to states of matter with long-range order is one of the central topics in condensed matter physics. Common types of order, such as ferro- and anti-ferromagnetic, are characterized by spin or charge densities modulated on inter-atomic scale, therefore well studied thanks to various scattering experiments. Order parameters that are not of this type are much more difficult to detect, giving rise to names such as hidden order or electronic nematicity. Their impact on transport or thermodynamic properties may, nevertheless, be substantial. In the EXMAG project we will investigate excitonic condensation in systems with strongly correlated electrons as a new mechanism leading to unconventional ordered states. The objective of the project is to characterize the physical properties of various excitonic phases and to find their realization in real materials. We will focus on intermediate coupling strength and doped systems where the interaction between the excitonic order and the charge carriers is expected to lead to new physics. In particular, we want to explore the potential of the excitonic order to induce instabilities, e.g. magnetic or superconducting, that are not present in the normal phase. We will also address the possibility of topologically non-trivial quasi-particle band-structures in the excitonic phase. Our main tool will be numerical simulations based on the dynamical mean-field theory and ab initio band-structure methods. We will pursue two main lines of research: investigation of simple models allowing access to many physical observables and studies of real materials capturing the chemical complexities at the cost of more severe approximations. Ultimately, we want to understand in detail the properties of the excitonic magne
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Radiation and Tumour Blood Vessels'.

assistant: **Objectives**

The tumour microenvironment plays a significant role in regulating tumour growth, metabolism, DNA repair, metastasis and response to therapy including radiation treatment. In particular, the oxygenation of a tumour greatly affects the response to ionizing radiation as hypoxic cells are more resistant to radiation then normoxic cells. Conversely radiation influences the microenvironment of the tumour by alterations in the tumour vasculature. With high single doses of radiation (>15Gy), vascular destruction is seen. At lower single doses or with daily fractionated doses (multiple smaller doses), there is little evidence of vascular destruction. Under some conditions tumour hypoxia is reduced after irradiation, potentially attributable to decreased interstitial pressure, increased perfusion and decreased oxygen consumption. Furthermore, apoptosis of the endothelial cells has been reported after tumour or intestinal irradiation. Attempts to enhance the efficacy of radiation therapy by using anti-angiogenic or anti-vascular agents however; have been limited by their transient nature. As this summary indicates, the effects of radiation on the tumour vasculature are still incompletely understood, but of substantial clinical importance. Therefore the aim of the proposed project is to delineate the vascular response in tumours to radiation. Direct observation of the vasculature during and after radiation with state of the art microscopic techniques should resolve many of these outstanding issues. Therefore we will a) develop experimental approaches to observe angiogenesis in murine tumours with video microscopy, b) determine the underlying mechanisms for vascular normalization and c) determine the nature of vascular response to radiation. These studies will help characterize the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'ADvanced SOILs for the agritech R&D' under Horizon Europe.

assistant: **Concept**

AdSoils project aims to evaluate, validate, and develop artificial advanced soil technology for its commercial exploitation as a tool forscreening crops from belowground.As part of the Farm to Fork strategy, the European Commission aims at reduced “nutrient losses of at least 50% by 2030, whileensuring no deterioration in soil fertility. This is expected to lead to a reduction in fertiliser use of at least 20%”. The breeding andagrochemical sectors are now seeking ways for crops to acquire water and nutrient more efficiently, supplying seeds, compounds andinoculum that reduce soil contamination and make crops more resilient to climate change. Assessing the effectiveness of suchstrategies is a major bottleneck because current screening technologies are destructive costly and time consuming.Within the ERC consolidator grant 647857 “SENSOILs”, an artificial soil that becomes transparent during watering has beensuccessfully developed. This technology, suited for small scale laboratory research, has shown great potential, enabling the discoveryof new forms of mobility by soil bacteria and mapping root induced chemical gradients at microscale resolution.Adsoils project proposes to move a step further and to demonstrate that the AdSoils solution can be fabricated and applied incommercial screens for the discovery of agrochemicals and genomic regions involved in water and nutrient use efficiency. Theproject will identify cost-effective fabrication routes enabling a close mimic of natural soils and will produce a sufficient volume tovalidate the soil prototype with industrial end-users.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Rigorous bounds on mixing in stratified shear flows: A route to improved parameterisations'.

assistant: **Concept**

Understanding the fluid dynamics of the atmosphere and ocean is critical to ensuring sustainable human activity. Specifically, understanding and parameterizing the response of the earth's oceans to thermal forcing is essential for the quality of long-term predictions of global climate change. One component of the oceanic response to thermal forcing is the small-scale irreversible mixing of fluid of different densities driven by vertical variations of velocity, i.e. within stratified shear flows. This project proposes to support the research of Dr Caulfield on this problem, through partially funding a Ph. D. student.This support will facilitate the rapid and permanent reintegration of Dr Caulfield into the European Research Area, and access Dr Caulfield's international network of research collaborators and experience. During this project, Dr Caulfield's research will improve existing parameterisations of stratified mixing by developing rigorous bounds on the amount of mixing which is possible within various stratified shear flows due to turbulent motions, using recently developed mathematical and computational methods. These methods are based around solving an appropriately formulated variational problem subject to physically reasonable constraints.They will then compare these predictions to the results of direct numerical simulations both to investigate the quality of the theoretical results, and also to suggest further constraints evident within the simulations, which could be applied to the theoretical problem. They will then use these results, through consultation with a multi-disciplinary international group of scientists, to construct improved parameterisations of shear induced stratified mixing for use in larger scale models.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'CoSt redUction and enhanced PERformance of PV systems'.

assistant: **Concept**

SUPER PV is pursuing an ambitious bus realistic goal for innovative PV system cost reduction and consequently significant LCOE reduction (26%-37%) by adopting hybrid approach combining technological innovations and Data Management methods along the PV value chain. To achieve that, key actions will be implemented at three main levels within the PV value chain: PV module innovation level, power electronics innovation level and system integration level. To ensure fast uptake of the project results by industry, state of the art modules (c-Si and flexible CIGS) and power electronics products were utilised for adopting innovations developed by research centres. For cost reduction in system integration and operation, Digitalization and Data Management solutions based on Industry 4.0 approach will be adopted following successful utilization of Building Information Modelling approach in the construction sector. Selected for uptake innovations will be compatible with existing manufacturing technological processes thus reducing impact on Cost of Ownership and ensuring attractiveness of proposed technologies for PV manufacturers. Prototype SUPER PV systems will be produced in industrial environments and tested in different (including harsh) climate conditions to evaluate cost efficiency and demonstrate competitiveness of the proposed solutions. On the basis of test results, business cases for technologies under consideration will be performed, plans for production and market replication will be prepared. Project activities will be complemented by wide training and dissemination campaign ensuring highest visibility and social impact of the project activities. By delivering to the market SUPERior PV products, the project will have twofold impact on EU PV sector: 1. Will create condit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'New light on innovation data, for enhancing regional competitive advantage' under Sixth Framework.

assistant: **Concept**

This project conjoins expertise in competitiveness and innovation scholarship with new capabilities in technology-driven data gathering and analysis by taking a lead from the proprietary methological knowledge of a world- class US-based research centre. In particular, the project aims to develop the nominated host research centre's (The Centre for Innovation and Structural Change (CISC) at the National University of Ireland Galway, Ireland) capacity to examine the critical under-pinners and embedders of innovation in a European region. Essentially, this project will utilise the novel data mining technique of vTHREAD (Techno-Historical Regional Economic Analysis Database) as developed by University of Massachusetts (UMass) researchers led by Professor Michael Best.This developed database and a set of complementary research tools designed to analyse regional industrial specialisation, growth, decline and reinvention are employed to populate a virtual laboratory of high-tech companies and then to 'interrogate' this population of companies and conduct experiments designed to shed light on the sources of industrial development and to enrich the concept of a regional innovation system. This project will thus generate and embed a research capacity to gather, analyse and disseminate very finely detailed innovation data in emergent and fast-changing high-technology clusters in the Border Midland and West (BMW) Region of Ireland (a less favoured region).While the centrality of innovation to the Region's future socio-economic development is widely acknowledged and routinely emphasised in European, national and regional policy strategy statements, this policy priority is not currently matched by a research capacity in the region for data gathering and integration, or for rigorous i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'ECO-innovative Energy FACTory Management System based on enhanced LCA and LCCA towards resource-efficient manufacturing'.

assistant: **Concept**

ECOFACT aims at enabling manufacturing industries to optimize the energy performance of their production systems in line with their relevant production constraints (time and resources), while at the same time introducing a novel green marketing approach through the concept of energy and environmental signature of the manufactured products from a life-cycle perspective. These results will be achieved from a data-driven approach thanks to the uptake of advanced ICT technologies, while better adapting to the consumer demands through customized sustainable production. The core of the ECOFACT platform as such, will be built at this high-level (Apps&Services) layer in a multi-service approach providing an innovative holistic combination of functionalities for advanced energy-efficient, sustainable process/product design and manufacturing management.


**Keywords:** LCCA, sustainable production, LCA, resource-efficient manufacturing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'The prevalence, cost and basis of food allergy across Europe' in the context of a Sixth Framework call.

assistant: **Objectives**

EuroPrevall is a multidisciplinary, trans-sectorial project involving Candidate Countries and SMEs. Its aim is to deliver improved quality of life to food allergy sufferers by developing knowledge- based holistic approaches to managing the problem. This will be achieved by integrating informationand tools related to: 1.Characterising PATTERNS and PREVALENCE of food allergies across Europe in INFANTS [birth cohortin 5 centres], CHILDREN and ADULTS [cross-sectional surveys in 10 centres]. Such studies of the wider population will be complimented by more detailed studies based on referrals to allergy clinics (12 centres). 2.Using samples and information from the surveys to IDENTIFY RISK FACTORS (environmental, microbial, genetic) and NOVEL PREDICTIVE MARKERS (biochemical or genetic) for food allergy would facilitate implementation of preventive measures e.g., during pregnancy. 3.DEVELOPING SEROLOGICAL METHODS based on purified food allergens ( component resolved diagnosis" ), including conventional and novel formats [such as protein and/or peptide chips] capable of IMPROVING THE QUALITY OF FOOD ALLERGY diagnosis and hence reducing need for confirmatory food challenge tests. 4.Investigating how the FOOD MATRIX AFFECTS THE ALLERGENICITY OF FOODS, including processing procedures, and developing new reference materials for food challenges which are truly blind and based on "real" food matrices, e.g. confectionary [THEME 3]. 5.DEVELOPING AND APPLYING INSTRUMENTS to determine the impact of food allergies on the QUALITY OF LIFE AND ITS ECONOMIC COST for sufferers/their families. These research outputs will be amalgamated in consensus positions on food allergy management from which TRAINING MATERIALS will be derived for ALLERGIC CONSUMERS, health professionals/ food industry. The
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Regreening Africa with natural regeneration' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The challenge. With 65% of agricultural land in Africa degraded, the need to effectively scale up restoration is evident. Natural regeneration (NR) is a promising restoration solution that depends on vegetation regrowing from seed or tree stumps, without the need to plant trees. However, we do not know what regenerates where and what benefits it may bring. What we do know comes from ecological studies on secondary succession that exclude human influences. This informs restoration poorly since people continuously use, manage and control NR. Aims. This study aims to 1) evaluate how NR develops over time and what benefits it brings, to 2) explore the optimal social-ecological conditions for NR-based restoration, and 3) predict the current and future NR restoration potential across Sub-Saharan Africa.Approach. Recent scientific breakthroughs in succession ecology and on-the-ground restoration developments offer exiting opportunities to gain new mechanistic insights into NR dynamics. I will: 1) Monitor woody vegetation in 150 unmanaged and managed agricultural fields across three ecoclimatic zones in Kenya. 2) Measure plot-level environmental and social variables that affect species performance. 3) Employ a trait-based approach to evaluate the relative importance of different regeneration mechanisms and consequences for multiple ecosystem functions. 4) Scale up mechanistic insights using large datasets and identify regional drivers of NR abundance, functional composition and diversity. 5) Predict climate change effects on NR and map current and future NR restoration potential across Sub-Saharan Africa.Impact. I will develop a mechanistic social-ecological framework for NR by integrating social dimensions into ecological theory, which allows to predict how NR contributes to r