RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'RATIONAL AND CLEAN USE OF ENERGY BY COMBINATION OF A NOVEL ABSORPTION COOLING MACHINE AND A PAFC AT A UNIVERSITY SITE', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

In this Thermie project the combination of a recently developed absorption heat pump and the promising fuel cell technology will be demonstrated. This combination creates the possibility of very high energy efficiencies, producing electricity and using heat for air conditioning and/or heating. Realization of this project will lead to a reduction of the energy demand. Because of the use of fuel cell technology, emissions will be very low. The demonstration will be at the University of Utrecht. This project will be used as a reference for other projects.Start of the project has taken place at the first of April 1996. The first intended location The Hotel of the Future" is cancelled. Activities concentrated on the selection of a new location, the set-up of a communication plan and an exploration study on the energy generation by the new combination.During the project a new inventory was made on the costs and a considerable deficit was observed. In view of the remaining financial deficit the partners have jointly decided to discontinue the demonstration project.In this Thermie project the combination of a recently developed absorption heat pump and the promising fuel cell technology will be demonstrated. This combination creates the possibility of very high energy efficiencies, producing electricity and using heat for air conditioning and/or heating. During the demonstration reliability and availability will be monitored. The 'Regionale Energie Maatschappij Utrecht' will supervise the demonstration.The demonstration will be at the University of Utrecht. By means of open days and publications a lot of publicity will be generated. Commissioning and preliminary measurements will take place at GASTEC Apeldoorn.To demonstrate the unique combination, a 200 kWe PAFC system will be
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Reagent kits instead of animals. In vitro methods to replace in vivo tests for immunotoxicity testing'.

assistant: **Concept**

Approved international standards for toxicology and allergy screening tests are in vivo methods. The use of experimental animals in the pharmaceutical and cosmetic indus constitutes increasing problems. Tests on animals are unethical, expensive and give unrelia results. Recent documented research progress can result in development of alternative in v methods. Human blood cells in with an allergenic substance release cytoki These can be assayed with immunoanalysis. Continued research will focus on the explora of the principle for the development of in vitrs} assessment of allergenicity and toxicity. V the scientific basis established, methods will be developed to produce generally applicabli vitro tests. Extensive comparative studies will be performed between these in vitro meth and current government approved animal tests. The research, development and clinical study assume a co ordinated network project including several countries. These studies will aim getting European approval for these in vitro methods as new standards. The advantages of methods will benefit the European pharmaceutical, cosmetic, food and chemical industries.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Identification of hox-regulated targets at different time points of a developmental process' (2002-2006).

assistant: **Innovation**

Hox genes are present in all animals with bilateral symmetry, providing a conserved mechanism to control regional differences along the body axis. However, little is known about the sets of genes that are modulated by the Hox proteins to mould morphologically distinct structures. The aim of this proposal is to analyse how the Hox proteins impinge on regulatory networks executing cell differentiation programmes. To study such a complex biological process, I will use as an experimental system the homeotic transformation of wing cells to haltere cells by the Hox protein Ultrabithorax (Ubx) in Drosophila melanogaster. By means of hybridisations to DNA microarrays, I will compare the transcriptome of control and Ubx-expressing wing discs. The sensitivity of these experiments will be enhanced by collecting additional microarray datasets from wing and haltere discs expressing an engineered form of Ubx with a potent transcriptional activation function. The way cells respond to Ubx changes several times during imaginal disc development. By employing a sophisticated expression system in Drosophila, I will identify the transcriptional targets of Ubx at different time points during larval and pupal development. All experiments will be done in duplicates, both with in vivo -processed discs and with discs cultured in vitro in the presence of the protein synthesis inhibitor cycloheximide. This will allow to distinguish between direct and indirect targets of Ubx. The biological significance of candidate targets will be verified by molecular genetic techniques and the relevant cis-regulatory regions will be retrieved by computational approaches. I will make use of this project to receive advanced training in complex genetic manipulations, whole-genome expression profiling, comparative g
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Predictive Modelling for Innovative Unit Management and Accelerated Testing Procedures of PEFC' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Premium Act is an ambitious project on the durability of PEFC (Polymer Electrolyte Fuel Cells), targeting one of the main hurdles still to overcome before successful market development of stationary fuel cell systems. PEFC systems are now very near, or even already comply with market requirements for cost and performance. But durability targets, up to several tens of thousands of hours, are much more difficult to reach.Premium Act proposes a very innovative approach, combining original experimental work on PEFC systems, stacks and MEAs (Membrane Electrodes Assembly), including locally resolved studies of components durability, components characterisation using the most advanced techniques in order to quantify ageing phenomena, and an original mechanistic, multi-scale modelling approach able to take into account materials degradation processes and all reactions occurring and competing at each instant in a PEFC.These combined experimental and modelling tools will provide understanding of the fundamentals of degradation, with new insight on the coupling of degradation mechanisms in PEFC components, thus enabling the consortium to innovate on:-operating strategies, enhancing lifetime of given MEAs in a given stack and system,-the design of a lifetime prediction methodology based on coupled modelling and composite accelerated tests experiments.Premium Act will establish this innovative approach on two strategic fuel cell technologies for stationary markets: DMFC power generators and CHP systems fed by reformate hydrogen, both sharing similar MEA materials. This will show that the strategy is adaptable to the multiple PEFC requirements and give a competitive edge to European providers of stationary fuel cell systems.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Universal system for microbial analysis of water quality to guarantee a safe and healthy agro-food sector' (GREENAQUA), addressing dissemination and exploitation.

assistant: **Impact**

GREENAQUA proposal is led by the Spanish SME Centro de Investigaciones Submarinas, S.L(hereinafter CIS) whose core business is environmental consulting specialised in ecology, biotechnology, biology, natural resources and R&D in the field of water. GREENAQUA is part of CIS business strategy to enlarge their business activity lines within water market related to agro-food sector. It is known that current quality of water resources of the planet is not as high as desired and major sources of water pollution are from human settlements and industrial/agricultural activities. Thus, GREENAQUA will be, at first, oriented to agro-food sector as key market segment, in order to extend afterwards its application to other sectors. The need to take care of this resource has become a global concern and a full monitoring of water quality along the whole hydrological cycle is required. Legislation is been adapted to this new situation and a higher demand of water analysis has appeared. Despite the market needs to have real-time water monitoring devices for biological and physical analysis, there are only few commercial solutions which can analyse both parameters. In general terms, currently, such parameters are determined by archaic systems and most of them require traditional techniques for laboratory cultivation and analysis. Likewise, several R&D sensors have been developed but their results are not very successful: the majority have not been validated in real scenarios and/or have limitations related to robustness, sensitivity, accuracy and reliability. In this context, GREENAQUA proposes a new product which is a Universal Water Monitoring Device for water quality analysis, in particular, to monitor Biological Parameters in order to guarantee water quality fulfils standards regardi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Neurons and modified CMOS integrated circuits interfacing' (NEUMIC), addressing dissemination and exploitation.

assistant: **Impact**

Biomedical devices increasingly rely on the use of silicon based microelectronic structures. We will develop generic technology to communicate reliably and functionally between living nuerons, and silicon (and GaAs) based molecularly modified microelectronic devices. The project focus on the multidisciplinary development of efficient nueron-electronic hybrids that allow for bi-directional electrical communication between nuerons and micro-devices as well as the construction of artificial chemical synapses between nerve terminals and postsynaptic transistors. The generic technology will serve as the base for the construction of biomedical microstructures that will functionally link nerves to robotic prosthesis and functionally link damaged neural networks. Biomedical devices increasingly rely on the use of silicon based microelectronic structures. We will develop generic technology to communicate reliably and functionally between living nuerons, and silicon (and GaAs) based molecularly modified microelectronic devices. The project focus on the multidisciplinary development of efficient nueron-electronic hybrids that allow for bi-directional electrical communication between nuerons and micro-devices as well as the construction of artificial chemical synapses between nerve terminals and postsynaptic transistors. The generic technology will serve as the base for the construction of biomedical microstructures that will functionally link nerves to robotic prosthesis and functionally link damaged neural networks.OBJECTIVESBiomedical devices increasingly rely on the use of silicon microstructures. To facilitate this development, novel concepts and a generic technology must be developed to enable reliable communication between living cells and silicon micro-devices. We focus the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'European Policy Co-operation of Women and Science' (EOWIN).

assistant: **Concept**

This Specific Support Action (SSA) aims to perform the preliminaries and preparations necessary to offer a seamless transition to a full ERA-NET in the field of women and science. The final goal is to coordinate the different national policies on the promotion of women in science and so eventually establish a European network of national policies on the promotion of Women in Science. Prior to establishing a functioning network, it is of great importance to intensify the cooperation and exchange of information at a strategic level between those responsible for the programmes in the field mentioned on the national and regional level. With the exchange of information on existing structures of national promotion, and the identification and definition of the probably different but also overlapping coverage and focus of each of the programmes of the partners, similarities and differences between the partners will have to be worked out and analysed. This analysis will provide the necessities for a profound benchmarking in the field. The recognition of good practice is an important goal in this process. This SSA also prepares the ERA-Net with regard to its future management and administrative structures. The naming of those responsible for the work packages of the future Coordination Action as well as the identification of experts in the field will be tasks and deliverables within the project. In addition, possible actions and necessary steps within the planned ERA-NET with a description of an adequate schedule will be outlined in order to set a basis for an immediate and smooth transition into the targeted project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Nonequilibrium pattern formation - solidification and epitaxy' under Fourth Framework.

assistant: **Concept**

Crystal growth in a liquid, or by molecular beam epitaxy results in complex patterns, from periodic cellular structures to spatio-temporal chaos (such as the Kuramoto-Sivashinsky dynamics), or completely stochastic (such as the Kardar-Parisi-Zhang situation). Their understanding is of paramount technological importance, while they offer at the same time interesting examples of spontaneous morphogenesis on the fundamental level, where one is often faced with a subtle interplay between stochasticity and determinism. We plan to study analytically and numerically the nonlinear evolution of surface morphologies on both a microscopic scale (such as step bunching and facetting), and on the mesoscale in the case of solidification. The analysis of the latter will be based on the free boundary integrodifferential formulation and finite elements techniques. We shall focus basically on the interaction between the diffusive instability and the elastic one [see recent account by the host group: C. Misbah et al. Phys. Rev. Lett. 76, 3013 (1996)].
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Bayesian markets for unverifiable truths' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Subjective data play an increasing role in modern economics. For instance, new welfare measurements are based on people’s subjective assessments of their happiness or their life satisfaction. A problem of such measurements is that people have no incentives to tell the truth. To solve this problem and make those measurements incentive compatible, I will introduce a new market institution, called Bayesian markets.Imagine we ask people whether they are happy with their life. On Bayesian markets, they will trade an asset whose value is the proportion of people answering Yes. Only those answering Yes will have the right to buy the asset and those answering No the right to sell it. Bayesian updating implies that “Yes” agents predict a higher value of the asset than “No” agents do and, consequently, “Yes” agents want to buy it while “No” agents want to sell it. I will show that truth-telling is then the optimal strategy.Bayesian markets reward truth-telling the same way as prediction markets (betting markets) reward people for reporting their true subjective probabilities about observable events. Yet, unlike prediction markets, they do not require events to be objectively observable. Bayesian markets apply to any type of unverifiable truths, from one’s own happiness to beliefs about events that will never be observed.The present research program will first establish the theoretical foundations of Bayesian markets. It will then develop the proper methodology to implement them. Finally, it will disseminate the use of Bayesian markets via applications.The first application will demonstrate how degrees of expertise can be measured and will apply it to risks related to climate change and nuclear power plants. It will contribute to the political debate by shedding new light on what
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Advanced Material And NAnotechnology Cluster' (AMANAC) under Horizon 2020.

assistant: **Objectives**

AMANAC targets to create an effective and long lasting collaboration and coordination platform within the EeB-PPP Advanced Materials and Nanotechnology projects, whose activities address development of (nano)materials, components and systems for the improvement of energy efficiency in buildings. The CSA aims to maximize the impact of the participating projects towards the European Industry and Society and support the objectives established by the EC and the EeB-PPP, in terms of Energy Efficiency in buildings.AMANAC exploits experience gained through clustering of Nanotechnology-EeB projects and extends the scope to include running FP7 and future H2020 projects of the Advanced Materials domain. It currently represents 26 projects and broadens their field of activities in a self-sustaining way.The Core Objectives and the resulting Action Plan develop around four pillars:• Collaboration Activities aiming to i) support the achievement of Cluster-project technical and non-technical goals; ii) enhance the impact of such developments during and beyond the project life-time; • Awareness-raising and Networking: Increase the visibility and impact of the Cluster projects and their related research achievements towards industry, construction stakeholders and relevant EU contractual bodies, such as the ECTP, the E2BA, ECCREDI etc., establishing appropriate network and alliances with such organizations.• Exploitation: Strengthen the role of involved industrial partners, especially SMEs, for speeding up the exploitation of the research results coming from the Cluster projects. Support the identification of new technology and market needs and trends.• Coordination and Support services: Create Cluster committees and bodies and publicity material to ensure continuation of activities afte
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Novel secretion systems of Mycobacterium tuberculosis and their role in host-pathogen interaction' (NOVSEC-TB).

assistant: **Innovation**

Tuberculosis is a major public health threat to the populations of Europe and the world. Mycobacterium tuberculosis, the etiological agent of the disease, can multiply and persist within phagocytic cells and this early event is of primary importance for the outcome of the infection. The main objectives of this proposal are to use highly innovative approaches in molecular and cell biology, biochemistry, immunology and imagery to elucidate the function and interplay of three families of immunogenic proteins of M. tuberculosis, the ESX, PE and PPE families. It was recently found that the ESX systems constitute novel secretion machineries that export major virulence factors and important diagnostic and protective antigens. While the ESX-1 system is responsible for the secretion of the prototypic ESX proteins, namely, the 6 kDa early secreted antigenic target (ESAT-6) and the 10 kDa culture filtrate protein (CFP-10), which are the most important proteins of M. tuberculosis involved in host-pathogen interaction, ESX-5 is implicated in the secretion of PE/PPE proteins. Restriction to pathogenic mycobacteria makes them highly interesting targets for host-pathogen interaction. The ESX-3 system appears to be essential. Thus, in this project we propose to --> analyse the global gene expression network of ESX-1, ESX-3 and ESX-5, --> determine the nature and diversity of the effector proteins they secrete, --> establish their mode of action and sub-cellular localisation, --> survey potential genetic variation in clinical isolates, --> assess their interaction with the immune system of the host, --> evaluate the suitability of ESX systems as drug targets, --> screen small molecules for their potential to inhibit ESX-mediated secretion. The  proposed approach will generate major insig