RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Fitness consequences of chromosome inversion polymorphism in mimetic butterflies' (FITINV) targeting Horizon 2020.

assistant: **Abstract**

Elucidating the fitness consequences of genomic innovations and variation is fundamental in understanding the process of adaptation and biological diversity. Chromosome inversions are important evolutionary events often associated with adaptation and cladogenesis. Inversion polymorphism is hypothesized to capture gene combinations favoured under certain environmental conditions, and by suppressing recombination, are thought to facilitate the segregation of co-adapted allelic variations. Nonetheless, little is known about the fitness components associated with inversions, nor their combined effect, be they synergistic or antagonistic, which determine their fate. The proposed fellowship aims to investigate whether inversions capture distinct traits whose combination produce distinct, locally adapted phenotypes, and to determine to which extent recombination suppression carries a fitness cost. The Neotropical butterfly, Heliconius numata, is an excellent model to tackle those questions. This toxic butterfly always displays a high polymorphism of predator-warning colour patterns within populations, with up to seven distinct morphs coexisting within a given locality. This perplexing polymorphism is under the control of a single supergene locus, and alleles associated with distinct morphs are characterized by different combinations of chromosomal inversions. The originality and the evolutionary relevance of the polymorphic mimicry inversions, as well as the availability of both genetic and ecological knowledge in this system, will enable us to significantly improve our understanding of the fitness consequences of inversion polymorphism, and will elucidate how biodiversity can be affected by the interaction of both ecological and genomic factors.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Visible-Light Active Metal Oxide Nano-catalysts for Sustainable Solar Hydrogen Production' under Seventh Framework.

assistant: **Concept**

The rising global interest in hydrogen as the fuel of future has prompted tremendous interest in the development of efficient hydrogen production technologies that may serve as economically viable solutions towards solar fuels.The project SOLARGENIX will investigate novel nanostructured photocatalysts starting from comprehensive theoretical and experimental investigations on visible-light active meta-oxides for photoelectrochemical splitting of water to target the environmental hydrogen production from saline water by sun illumination. For this purpose, efficient multi-functional photoactive nano-catalysts will be developed whereby underlying atomic understanding of elementary chemical reactions and electrochemical processes will guard the scope of the project. The development of efficient nano-catalysts will be mastered by novel material combinations and  interfacial engineering in nano-hetrostructures.Furthermore the project will demonstrate the feasibility of this technology together with industrial partners to develop first module-sized demonstrators for testing under real operating conditions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Sustainable Heat and Energy Research for Heat Pump Applications /Acronym SHERHPA', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

Sustainable energy systems, such as heat pumping technologies, provide an efficient use of renewable energy from the ambient and of waste heat sources. Typical applications are space heating, domestic hot water and processes with combined heating and cooling. Doubling the number of heat pumps in Europe by 2010 would increase the annual energy and CO2 emission savings to 100 TWh and 40 million tons respectively. To achieve such an ambitious target on European level and to support the creation of a strong market impact, in addition to the European Heat Pump Association, EHP A1(policy, strategy and marketing) and the European Heat Pump Network, EHPN (dissemination of information, Website) a dedicated project towards SMEs is jointly proposed GRETh (Heat Equipment Association) and EHP A This project deals with the development of heat pumps that are cost-energy efficient and in compliance with the future environmental regulations.The new environmental regulations, concerning greenhouse gases and the protection of the ozone layer, will lead to the phase out of conventional refrigerants. For example, in the EC the 'Freon' R22 phase out is scheduled in 2010.Therefore 'natural fluids' have to be adopted (hydrocarbons, carbon dioxide or ammonia), but this implies a change in the components technology and control system. Heat pumps are components that allow energy savings for heating and cooling buildings and for many industrial applications, and concern a very large spectrum of applications much wider than the existing heat pump market. During the first half of the project, components and subsystems (heat exchangers, controllers, ground coupling system, heat recovery...) will be developed, tested and optimized. Afterward, during the second half of the project, prototypes will be d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Preparation of ALLegro - Implementing Advanced Nuclear Fuel Cycle in Central Europe' (ALLIANCE).

assistant: **Concept**

The ALLIANCE project focuses on the preparatory phase for developing the ALLEGRO demonstrator. This is based on the Gas Fast Reactor (GFR) concept, one of the 2 alternative systems under the SET-Plan’s European Sustainable Nuclear Industrial Initiative (ESNII), expected to be built in Central Europe. ALLIANCE covers a number of preliminary studies on fuel management, R&D roadmap & infrastructures needs, and siting, as well as the licensing roadmap, preliminary design and safety analysis. ALLIANCE will integrate experience and knowledge gained from the past or ongoing related initiatives.Arguments on why GFR technology could be accepted in Europe as a complementary option of SFR will be clearly stated. Furthermore map and highlight of national or regional initiatives supporting the development of this technology and list of countries interested in the hosting of the ALLEGRO demonstrator on its territory. The conditions for the site selection should be defined within this project.In addition the project specification on licensing and construction period will be suggested. For the R&D activities as well as for the operational and decommissioning phases specifications should be elaborated. These specifications would cover the licensing roadmap, financing and project organisation setup.According to the latest concept, a common Centre of Excellence will be created in Central Europe for GFR studies. The creation of the Centre will be the first step towards integration of fuel and reactor safety research in the region.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Development of heating technologies for the Efficient renewable Energy COnsumption of CO2-neutral DOWNSTREAM-processes' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

The aim of E-ECO Downstream is to enable a clean steel production by developing advanced and breakthrough technologies for the steel making downstream processes. This will decisively support the EU in achieving its goal towards climate neutrality by 2050.E-ECO Downstream focuses on the efficient utilization of hydrogen, biogas, and electricity to substitute carbon-based fuels and drastically lower the carbon footprint of the steel production. Energy efficiency is pursued to enable sustainable utilization of volatile green energy. Currently installed burners of reheating furnaces will be enabled to utilize green H2 by integration of newly designed and 3D-printed burner components instead of replacing entire burner systems. To increase fuel flexibility hybrid heating concepts (H2 and electricity) will be investigated in a pilot walking beam furnace. Since the mentioned solutions will change the waste heat streams and their heat recovery in future downstream processes must be reevaluated. This will be done by analysing the partners processes and plants, development and testing of waste heat recovery concepts and recuperators regarding their suitability to new fuels and their off gases, while considering their impact on materials/product. Energy efficiency potentials of downstream processes will be evaluated by case studies for the application of hot charge from casting to hot rolling by covering of the slabs with passive and active panels.The elaborated solutions will be assessed by techno-eco-environmental analysis to evaluate their applicability and to increase their acceptance in the steel community.The E-ECO Downstream consortium has a deep and shared knowledge of iron and steel making, downstream processes and heating technology, materials engineering, numerical simul
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Uncovering the molecular and cellular mechanism of tumor dormancy for the rational design of theranostic nanomedicines' under Seventh Framework.

assistant: **Concept**

Tumor progression is dependent on a number of sequential steps, including initial tumor-vascular interactions and recruitment of blood vessels, as well as an established interaction of tumor cells with their surrounding microenvironment. Failure of a microscopic tumor, either primary, recurrent or metastatic, to complete one or more of these early stages may lead to delayed clinical manifestation of the cancer and a state of stable non-progressing disease. Micrometastasis, dormant tumors, and residual tumor cells contribute to the occurrence of relapse, and constitute fundamental clinical manifestations of tumor dormancy that together are responsible for the vast majority of cancer deaths. However, although the tumor dormancy phenomenon has critical implications for early detection and treatment of cancer, its biology and genetic characteristics are poorly understood. We now propose to investigate the molecular and cellular changes in tumor-host interactions that govern tumor dormancy, which may lead to the discovery of novel tumor dormancy targets and provide tools for dormancy-dependent tumor therapy strategies. In order to achieve this goal, we will integrate the following basic and translational approaches: (i) Establishment of mouse models of dormant and fast-growing tumor pairs; (ii) Functional and molecular characterization of dormant versus fast-growing tumors, (iii) Design of dormancy-promoting tailor-made polymer therapeutics delivering a combination of microRNAs with chemotherapies; (iv) Polymer conjugation to a prodrug designed to be activated by specific enzymes overexpressed in tumors, Turning-ON a near infra-red (NIR) fluorescence signal.When completed, this proposal will shed light on this fundamental cancer biology phenomenon. A better understanding of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project '5G for future RAILway mobile communication system'.

assistant: **Objectives**

The Future Railway Mobile Communication System (FRMCS) will be the 5G worldwide standard for railway operational communications, conforming to European regulation as well as responding to the needs and obligations of rail organisations outside of Europe. The work on functional & technical requirements, specification & standardisation in 3GPP as well as regarding harmonised spectrum solutions is currently led by UIC, in cooperation with the whole railway sector. A major challenge is the update by European Railway Agency of the Technical Specifications for Interoperability of Control Command and Signalling (CCS TSI) by the end of 2022 with a full description of FRMCS with respect to interoperability functions. Therefore, the 5GRAIL project aims to verify the first set of FRMCS specifications and standards (FRMCS V1) by developing and testing prototypes of the FRMCS ecosystem.The validation of the latest available railway-relevant 5G specifications will be achieved through cross-border emulation trials covering significant portions of railway operational communication requirements and including the core technological innovations for rail expected from 5G release 16 and pre-release 17.The project will first define functional tests and then work towards the development and evaluation of prototypes, for both on-board and infrastructure, including vital (ETCS, ATO) and essential (voice specific services, TCMS and video) applications. Prototypes will be then tested in simulated and real environments, with pilots in labs and in the field rolled out in various European sites (France, Hungary and Germany), to ensure compliancy and validation for FRMCS specifications, standards and performance, and consequently guarantee the time to market for FRMCS deployments, planned for 2025 as
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Tailoring Enzymes for Natural Product Synthesis'.

assistant: **Objectives**

The aim of the project is to translate the knowledge from biosynthetic pathways of natural products into Organic Chemistry, achieved by developing novel chemoenzymatic total syntheses of the polyketide natural products ambruticin and jerangolid. In both biosynthetic pathways, large parts of the molecular complexity are set up by tailoring enzymes. These enzymes will be studied regarding their potential to act as biocatalysts that can substitute late and crucial steps in total syntheses.The project divides into two parts. At first, the biosynthesis of ambruticin and jerangolid will be studied with a focus on allocating particular steps to individual tailoring enzymes. These enzymes will be characterised in in vitro assays and these assays will be optimised in order to find out if the candidate enzymes can be applied as efficient biocatalysts. After this, total syntheses will be developed, which integrate these enzymatic steps. This approach promises to gain several advantages. The overall efficiency of the syntheses could be drastically improved and the access to derivatives could also be considerably facilitated. Furthermore, the project will gain substantial knowledge about tailoring processes of complex polyketide pathways.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Forensic Analysis of Concrete Through Image Processing' (FACIP) under Horizon Europe.

assistant: **Objectives**

The proposal is about the Forensic Analysis of Concrete through Image Processing (FACIP), which offers several improvements over traditional methods of forensic analysis (FA) of concrete. Unlike manual inspection, the proposed method automates and streamlines the process, reducing human effort and evaluation time. FA of concrete is commonly used to determine particle size, shape, aggregate ratio, porosity, and other physical characteristics that affect concrete performance. This project aims to develop an innovative approach that utilizes image processing (IP) and Convolutional Neural Networks (CNN) to enhance FA of concrete structures. By accurately and efficiently detecting, characterizing, and quantifying various concrete defects such as cracks, spalling, corrosion, and delamination, the project aims to extract intricate patterns and features from concrete images through deep learning, improving FA accuracy. This ambitious objective pushes the boundaries of current research in FA of concrete, opening the door to discoveries and advancements. By combining IP and CNN for FACIP, the research aims to develop innovative methodologies and tools that surpass the limitations of existing techniques, such as Core Cutting, Schmidt Hammer, and UPVs, providing accurate and reliable analysis results. This contributes to developing more effective concrete maintenance, repair, and structural integrity assessment strategies. Ultimately, the project aims to provide concrete forensic experts with advanced, reliable, and time-efficient analysis methods, enhancing concrete forensic investigations' overall accuracy and effectiveness.


**Keywords:** Forensic Analysis of Concrete, Image Processing, Convolutional Neural Networks, Compressive strength
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Performance optimization of two-phase passive loop system' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Innovative heat transport devices are needed to break-though the increasing need for smaller, faster and lighter microelectronic apparatus. A Pulsating Heat Pipe (PHP) is a promising two-phase passive loop device that has many advantages such as high heat transfer capacity, construction simplicity, lightweight, and low-cost. However, the practical use of PHP has been limited due to insufficiency of design tools, i.e. predictive models for hydrodynamic and heat transfer phenomena. The aim of this proposal is to establish a universal model to predict operating limit of PHP and provide an optimal design solution that maximize PHP heat transport capability. An innovative approach using advanced measurements with high-resolution and high-speed infrared cameras and Inverse Heat Conduction Problem (IHCP) techniques will be taken to reveal the local thermal phenomena of the liquid-vapor interaction and obtain important physical parameters to implement the model. Both an experimental and a modelling approach will be used to reach the project goal.The project will bring together two complementary set of skills, with the researcher’s expertise in PHPs and the supervisor’s expertise in thermal tomography. In addition, a secondment in a leading company of two-phase thermal devices is foreseen, to increase the researcher’s competence in manufacturing and testing. The fellowship will support the researcher’s professional development to be a leader in the thermal fluid dynamics field. The impact of the action will be maximized with scientific publications as well as a broad range of outreach activities such as video pills and public talks to non-technical audiences, with a special target to young females to booster research careers in technology and engineering. Results of this MSCA ha
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'NANOSTRUCTURED ALUMINA WAVEGUIDES FOR DUAL-OUTPUT BIOSENSING: STRESS INDUCED FABRICATION AND CHARACTERIZATION' (NANOSTRBIOSENS).

assistant: **Innovation**

Most commercially available optical biosensors only measure changes in the refractive index of a solution very near the sensor surface.  Information given by this approach is limited to the amount of analyte molecules linked into receptors on the sensor surface. In some cases, understanding complex bio-events is constrained when available data is based solely on refractive-index-change measurements via characteristics of the reflected light (intensity, polarization or phase). Scattering measurements need to be accompanied along with reflection measurements in order to determine the organization of molecules on a surface as well. This proposal calls for the development of nanostructured waveguides made of a thin layer of alumina (Al2O3) which would produce and control dual sensor outputs, specifically, total internal reflection (TIR) and surface enhanced Raman scattering (SERS) signals. Single-mode waveguides with structured surface will present a significant advantage over current optical biosensors by providing better information about both the binding and organization of protein molecules via polarization maintained reflection and scattering. After atomic layer deposition of single-mode waveguide alumina film, its surface modification will be done by a mechanics driven fabrication method called thermal stress induced hillock formation. The main objective of this proposal is to fabricate and characterize a nanostructured alumina waveguide that will provide the following crucial advantages over the optical biosensor approach: 1) The possibility for dual-output with fine tuning, 2) a more complete understanding about the organization of molecules, 3) an unprecedented sensitivity for a label-free optical sensor, which will analyze information down to sub pmol/cm2 because