RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'METABOLIC CONTROL OF IMMATURE STROMAL CELL BIOLOGY' (METABOSTEM), addressing dissemination and exploitation.

assistant: **Impact**

A very recent literature claims that metabolic status represents a crucial regulatory mechanism that helps direct stem cells fate. Whereas mainly described on the well characterized hematopoietic stem cells population, such metabolic investigations have been poorly conducted on another key population of adult immature cells that populate the stromal compartment of all tissues, i.e. the mesenchymal stromal/stem cells (MSC). Among them, adipose-derived stromal/stem cells (ASC) have been defined both as multipotent precursors and as supporting cells through their high secretory and immunomodulatory properties. These ASC hallmarks explain their potent regenerative capacities and have prompted clinical studies on their therapeutic potential. However, the mechanisms that govern their plasticity and fate as well as their interactions with other cell populations still remain to be unravelled. Along with ASC, adipose tissue harbours other immature populations whose biology is poorly described. The main objective of this METABOSTEM project is to investigate the role of metabolism in the intrinsic biology and fate of immature stromal populations residing within adipose tissue. Based on neuron-astrocyte and cancer cells models, we hypothesize that supporting cells such as ASC control the surrounding immature populations through a metabolic coupling, representing a new and primitive mechanism by which stromal compartment could control stem cells biology within the niche. This interdisciplinary project will integrate different scientific fields and techniques together such as in situ analysis, metabolic characterisation and stem cell biology, using murine adipose tissue as a working model. The METABOSTEM proposal will hopefully help at a better understanding of the biology of immatur
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Developing & marketing future foods the challenge of communication' in the context of a Fifth Framework call.

assistant: **Objectives**

The objective of this proposal is to enable organizing the international congress Developing and Marketing Future Foods - The challenge of communication" on 7-9 June, 2000. The objective of FFOOD-2 congress is to provide a forum where food and marketing professionals, and consumers' representatives can meet. The goal is to improve the communication between these groups in the future. The project will consist of four work packages, which will enable the organizing of the meeting. First work package contains the preparation tasks. The second work package is a call for participants. The third work package is for preparing the congress proceedings and fourth is the actual meeting itself. The high quality lectures during the three-day meeting, the symposium proceedings and the website will ensure good dissemination of the symposium material ."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Entanglement for quantum information with ion strings'.

assistant: **Concept**

Entangled states of many particles are arguably the ultimate feature of quantum mechanics. Such states, promise to deepen our understanding of fundamental aspects of the quantum world and its transition to the classical, as well as the realization of fault-tolerant and resource-efficient quantum computers. We propose to experimentally investigate both fundamental and practical aspects of multi-particle entanglement with strings of 10 to 20 trapped atomic ions (40Ca+). This fellowship will help to strengthen QIP research in the European Union while acquiring the expertise of the fellow.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Creating the first Social Responsibility Shopping platform to link small businesses and local non-profits organizations through an innovative business model leveraging on responsible consumption' (2014-2020) under Horizon 2020.

assistant: **Objectives**

SRS - Social Responsibility Shopping is an innovative business model, conceived by Citybility, that allows on one side small retailers to do Corporate Social Responsibility marketing as if they were big companies, on the other side local charities to do fundraising as if they were more famous charitable organizations.In times when consumers are more interested than ever in doing business with companies they know and respect, Corporate Social Responsibility marketing is becoming a crucial strategy to position the brand in the mind of consumers and consequently push sales.Thanks to SRS digital platform, small retailers can sustain a charity nearby, and attract customers that share the same ethical values, by giving money every time a transaction is made through SRS. While helping shopkeepers to develop their business, SRS aims to support thousands of local charities to carry out their projects, and even encourage citizens to establish new charities. SRS is expected to stimulate local fundraising and to sustain local consumption at the same time, permitting local economy to thrive.SRS’s novelty consists in a win-win-win solution. Three times “win” because it is based on three players (shopkeepers, charities, consumers) that working together generate a virtuous circle with a win solution for each of them: shopkeepers grow their business, charities have their operations funded, consumers feel that their shopping is helpful and not frivolous.Given that SRS is already planned to be launched in Italy by the second half of 2015, the specific objectives for the feasibility study are: 1) to define the attractiveness of potential international target markets to develop SRS on a European scale; 2) to assess the customers responsiveness, the ability to win and the most critical facto
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Human toll-like receptor family in chronic and degenerative diseases'.

assistant: **Objectives**

There is a pressing need for more effective treatments for chronic degenerative diseases such as rheumatoid arthritis (RA) and inflammatory bowel disease (IBD) This proposal aims to resolve the molecular mechanisms which underlie these diseases by focusing on the highly novel family of toll-like receptors TLRs) whose members have been linked with onset and progression of inflammatory diseases The proposal plans to explore all aspects of TLR biology, from regulation of their expression, to mechanism of action, to role in inflammatory diseases Several key technologies will be used, including the generation of knockout mice, animal model of disease, analysis of clinical samples, genomics and is predicted that such a multidisciplinary approach will define the role of TLRS in RA and IBD and will suggest new therapies fore these debilitaing diseases
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Phosphorus MR Spectroscopic Imaging of Brain Tumors at 3T' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Phosphorus magnetic resonance spectroscopy (31P MRS) is a non-invasive MR imaging technique that can provide in-vivo quantitative information about the energy metabolism, the oxygen state and the pH within a given region of interest. 31-Phosphorus (31-P) is fifteen times less abundant in tissue than proton (1-H) leading to a higher interest of proton spectral imaging at low field strengths. In-vivo phosphorus spectral imaging has recently become more popular with the availability of higher field 3T MR scanners due to the increased signal to noise ratio and higher spectral peak separation. In this study, we propose to implement phosphorus spectra at high field strength of 3T to diagnose and characterize brain tumor patients. The first part of the study will be the data acquisition and reconstruction development and optimization. Phosphorus spectral data will be acquired both using a single surface 31-P coil and a birdcage dual tune 1H/31P head coil. Single voxel data will be acquired from a region of interest encompassing the tumor or normal tissue. T1 relaxation characteristics for phosphorus metabolites in brain tumors and normal brain tissue will be defined. The data reconstruction and analysis will be performed using both time and frequency domain analysis techniques and their results will be compared. In the second part of the study, two dimensional phosphorus spectral data will be acquired using a birdcage coil, and the heterogeneity of phosphorus spectral parameters within the grade II, III and IV brain tumors will be analyzed. Additionally, a metric that can quantitatively and objectively assess the aggresiveness of brain tumors using the intensities of phosphorus containing metabolites will be presented.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Towards a Unified Macro-Distributional Analysis of Globalization' (TUMAG), addressing dissemination and exploitation.

assistant: **Impact**

Which social groups have most benefitted from financial globalization since the 1980s? How would inequality have evolved if, instead of tax competition, countries had chosen tax harmonization? The goal of this project is to address these questions in a unified framework and using new data. This proposal builds on my previous work and consists of two parts. First, I will create prototype Global Flows of Funds: comprehensive statistics of the ownership of global assets by country of the owner and wealth group (e.g., amount of UK real estate owned by US households in the top 1% of the wealth distribution). Current macroeconomic and inequality data do not indicate which groups of the population own external assets in different countries. To remedy this, I will generalize my earlier work on the size and distribution of offshore wealth to all external assets, leveraging recent major improvements in global wealth data. The resulting database will provide a direct measure of the share of foreign assets in the portfolios of different wealth groups (e.g., fraction of the wealth of the US top 1% invested in foreign assets), bridging the gap between the study of inequality and financial globalization. Second, using these Global Flows of Funds, I will estimate the effect of international tax competition on inequality. I will first provide a comprehensive quantification of the rise of international fiscal externalities since the 1980s, i.e., the extent to which residents of a given country have increasingly been subject to taxation in other countries (e.g., tax havens). Using multi-country models of wealth accumulation with heterogeneous agents calibrated using Global Flow of Funds data and other sources, I will then simulate the counterfactual evolution of inequality under different
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Researchers' Mobility Assistance in Iceland'' (2002-2006).

assistant: **Innovation**

Destination: ERA is a project designed to increase mobility of researchers between Iceland and Europe and attract researchers from outside Europe to the European Reserach Area. In order to realize this, RANNIS will create a network of universities, enterprises and governmental agencies, removing barriers to researchers' mobility and providing information and assistance to mobile researchers. A centralized mobility centre will be established in Reykjavik to co-ordinate this network and organize its activities. The centre will also serve as the primary entry point for researchers looking for practical information about living and working in Iceland and set up a national mobility portal. RANNIS will serve as a bridgehead organization towards the European network of mobility centres. The project will be carried out within three periods of activities, a preparation period, kick-off period and a period of specific activities. Some activities will be on-going during the whole project period. The aim of all those activities is to develop a model of researchers' mobility assistance to be carried on after the end of this project and community support. By the end of the project period, three goals should have been realized: 1) To enhance knowledge and create understanding about researchers' mobility, in order to help developing quality assistance to mobile researchers and their families as well as to evaluate results of such actions over time. 2) To develop services and proximity assistance to mobile researchers by various means of information dissemination and personal assistance offered by a centralized mobility centre. 3) To create an Icelandic mobility network, including universities and research institutes, governmental agencies and enterprises, in order to incorporate all re
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Mechanical Oocyte Measurement as a predictive biomarker for Assisted Reproductive Technologies' (MOM-ART) under Horizon Europe.

assistant: **Objectives**

Infertility is a major societal problem and one in six people must use assisted reproductive technologies (ART) to conceive. However, ART success rates remain low (ca. 20%), which represents a significant burden for the patients due to the heavy treatments and high risk of miscarriage. Recent studies have revealed that the mechanical properties of female gametes (oocytes) are tightly regulated and can change with advancing maternal age (AMA), leading to a higher risk of miscarriage or congenital diseases. Mechanical biomarkers have thus been proposed to score “high-quality” oocytes in ART. However, their use is hampered by (1) the lack of precise knowledge of mechanical phenotype(s) associated with AMA and oocyte quality, and (2) the absence of appropriate technology to measure oocyte mechanical properties in medical settings. In MOM-ART, I propose to develop a user-friendly and non-invasive approach for the mechanical phenotyping of oocytes based on an innovative miniaturized measurement system with computational analysis. I will characterize mechanical phenotypes associated with AMA and/or developmental defects in mouse models to establish the predictive value of mechanical biomarkers for oocyte quality. I will finally evaluate the proposed microfluidic approach in a reproductive medicine department, in the frame of a non-academic placement, and aim thereby to identify minimal requirements that my approach and device must meet to be applied for oocyte mechanical scoring in medical setting. This comprehensive and interdisciplinary project will bring significant technological, fundamental, and medical advances in oocyte mechanobiology, directly applicable to oocyte quality assessment and personalized diagnostics in ART. In MOM-ART, I will interact with experts in microf
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Autonomous vehicle for underwater inspections'.

assistant: **Concept**

This project proposes the research in reactive path planning for mobile robots in real environment using artificial intelligence (AI) techniques. An experimental prototype will be used in a first stage as a test bed for proposals (an autonomous underwater vehicle ? AUV). Among the multiple disciplines that converge in the development of a cost effective and useful for inspections AUV, the navigation control as well as the path planning exhibits particular interest. Effectively, although a lot of proposals may be found in the literature since the last decade, there is a lack of a reliable set of tracking and obstacle avoidance systems to allow the vehicle to follow a certain pattern in the seabed. A potential application is pipeline, electric and telephone cables tracking. However, the scopes of this research are not limited to this application (i.e., study of coastal ecosystems). Thus, given the multiple possible scenarios in an underwater world, AI techniques will be used to cope with these unknown situations. To face them it requires safe navigation systems that are not yet available for autonomous operations. The main objective of this project is to design and to develop a cost-efficient technology for autonomous navigation in complex environments. The project includes development of an autonomous tracking and safe low-altitude navigation for an AUV prototype, which could handle sea trials. The particular objectives are: 1. To develop a software module responsible for providing the desired AUV trajectory, resorting to AI techniques, particularly knowledge-based system; 2. To apply the resulting prototype to subsea pipeline and cable inspections (in 1 and 2 this project is linked to the EU AUTOTRACKER-GRD1-2000-25150); 3. To develop a mobile robot laboratory in the ou
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Deep Label-Free Cell Imaging of Liquid Biopsies for Cancer Monitoring' (LF-LB).

assistant: **Innovation**

We will develop and commercialize an innovative device for diagnosis and monitoring of cancer in liquid biopsies based on a label-free interferometric phase microscopy (IPM) unit, coupled with dedicated real-time artificial intelligence (AI) for cell classification. This device will materialize an innovative approach for the much-anticipated imaging flow cytometry, dramatically decreasing its costs, and improving patient care by accurate monitoring of cancer in the clinical lab from a simple lab test (liquid biopsy). The success of the project is dependent on four high-risk/high-gain aspects: (a) Building the first clinical IPM device. (b) Designing and manufacturing a disposable microfluidic device for imaging flow cytometry. (c) Obtaining high-enough acquisition and processing throughput in imaging flow cytometry of urine samples. (d) Training a deep natural network to detect cancer cells based on the information-deep label-free IPM images of cancer cells during flow. The proposed PoC project stems from my on-going ERC StG project that focuses on the application of IPM for grading the metastatic potential of cancer cells, as a basic-science research tool.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Designing Effective Public Policies' (DEPP) under Horizon 2020.

assistant: **Objectives**

This proposal outlines a number of projects in public economics, with links to other fields such as macro, real estate, labor, and gender economics. The projects evolve around several large administrative datasets from the UK and Denmark, and they advance approaches and methodologies that have recently been developed in public economics into new areas. There is a strong public policy focus running through the proposal, including tax policy, transfer policy, family policy, and indirectly monetary policy. The objective is to achieve a comprehensive understanding of how government interventions affect two key markets: the housing market and the labor market.The project is divided into two themes. The first theme focuses on the housing market and is divided into three subprojects. The first project investigates the effects of mortgage interest rates on leverage and house prices, and it develops a new quasi-experimental method for estimating the elasticity of intertemporal substitution in consumption, a crucial parameter for many public policies. The second and third projects investigate housing market responses to different tax policies, focusing on how such responses are magnified by liquidity constraints and leverage.The second theme focuses on the labor market and is divided into two subprojects. The first project studies secular changes in gender inequality and the underlying sources of those changes, focusing mainly on the effects of child rearing on gender inequality. The project explores the underlying mechanisms driving child-related inequality, including gender identity norms and family policies. The second project proposes a new way of estimating macro labor supply elasticities that integrates taxes and public expenditures, and it develops a theoretical framework