RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Digitally Integrated Scientific Data for Patients and Populations in User-Specific Simulations' under Seventh Framework.

assistant: **Concept**

The DISCIPULUS SA aims at the grand challenge of the 'Digital VPH Patient'. It is an avatarof the models and individual data that allow health prediction and disease treatment whenthe 'Digital Me' of a citizen needs to avail itself of health services. In essence, it constitutes arevolutionary Clinical Prediction and Decision Support System. To realise this vision,DISCIPULUS develops a sound ICT research and innovation roadmap, informed byconsultation and engagement of diverse groups from modellers and technology developersto end users, healthcare providers and regulators. The final goal is to deliver a single,universally useful, all-encompassing VPH-based avatar.To prepare for this, DISCIPULUS consolidates relevant RTD results by examining criticallythe state-of-play of both research and innovation throughout the VPH Community. Itdocuments and maps output central to the successful realisation of the Digital Patient. Itcaptures and quantifies the needs of stakeholder communities, particularly those ofclinicians and patients, which are key for the crafting of a successful, usable Digital Patient.The structure of DISCIPULUS has been designed to optimise interactions betweenworkpackages. Technical activities (analysis of scientific/technical challenges,translation/clinical scenarios) & roadmap production are facilitated by operationalactivities (management, community building/engagement, dissemination).The five consortium partners, supported by global experts, assemble all the expertiseneeded to assure excellence of the final roadmap. DISCIPULUS lasts for 18 months, theminimum time span to fully engage the VPH community and the diverse stakeholders, andto deliver high quality results. Effort of 145 PMs is estimated, EC contribution solicited isabout €1.4m, with substantial
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'In Situ Observation of Batteries for Extending Lifetime', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Lithium-ion batteries (LIBs) are a key technology in enabling the transition from a dependence on fossil fuels towards renewable energy sources. However, increased energy density, cycle life, and recyclability are still needed. The different degradation processes in the LIBs are hard to disentangle from post-mortem measurements alone, as intermediate species cannot be detected and changes may occur during cell disassembly. This project aims to apply novel in situ techniques to directly observe the processes involved in transition metal (TM) dissolution, how this affects electrolyte decomposition at the cathode and anode, and the effect on the stability of the solid electrolyte interphase layer. This will be achieved via novel in-situ X-ray photoelectron spectroscopy (XPS) and x-ray absorption spectroscopy (XAS) measurements that allow electrodes and electrolyte to be simultaneously observed during cycling. This understanding will be used to develop solutions to mitigate TM-dissolution and its impact on cycle life. The focus will be LiNixMn(1-x)/2Co(1-x)/2O2 (NMC) electrodes used in many commercial LIBs, where larger energy densities can be achieved by increasing the nickel content. However, this is accompanied by higher levels of side-reactions from the more reactive surfaces. The electrolyte degradation products coming from NMC materials with different nickel content will be identified and prevented from reaching the graphite electrode by using lithium-ion conducting glass to separate the electrodes. This will help finding out how Ni-rich NMC materials can be stabilized and the extent to which cross talk products contribute to ageing. The project will also investigate new ways to recycling aged NMC to enable their re-use in new cells, decreasing the energy consumption
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Multi-Role Shadow Robotic System for Independent Living' in the context of a Seventh Framework call.

assistant: **Objectives**

The project focuses on the development and prototyping of remotely-controlled, semi-autonomous robotic solutions in domestic environments to support elderly people. In particular, the SRS project will demonstrate an innovative, practical and efficient system called shadow robot" for personalised home care.<br/>Most elderly people want to live in the familiar environment of their own residence for as long as possible. However, not many can live with their adult children and therefore, at some stage, often late in life, have to live alone. Studies show that some forms of home care are usually required as they advance in years.SRS solutions are designed to enable a robot to act as a shadow of its controller. For example, elderly parents can have a robot as a shadow of their children or carers.  In this case, adult children or carers can help them remotely and physically with tasks such as getting up or going to bed, doing the laundry and setting up ICT equipment etc. as if the children or carers were resident in the house. This objective will be realised through the following SRS innovations:1) A new intent-based remote control mechanism to enable the robots to be tele-operated over a real-world communication network robustly. 2) An adaptive automation mechanism to enable a highly efficient task execution for remotely controlled service robots. 3) A new robotic self-learning mechanism to enable the robots to learn from their experience.  4) A safety-oriented framework derived through extensive usability and user acceptance studies that enable service robots to be effectively deployed into home care applications.The shadow robot prototypes created with EU support in the SRS project will be tested at the "S.Maria Nascente" Centre in Milano and the IZA Care Center in San Seba
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Perceptual Analysis and Simulation of Real-World Materials Appearance' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The main goal of this project is to identify relationships between human perception of real-world materials properties and corresponding computational features. We will use Bidirectional Texture Functions as state-of-the-art digital representation of illumination and view dependent real-world material appearance as initial data for our analysis. We believe that rigorous analysis of human perception of individual visual effects in different material samples will allow us not only understand principles of human perception of real material surfaces but also to develop more efficient acquisition, modelling, and editing methods for this type of massive but highly photorealistic data. The observed material properties are surface specularity, translucency, roughness, anisotropy, directionality, back-scattering, among others. We will study the perceptual importance of these properties as well as their mutual dependency and dependency on type of material and illumination and viewing conditions. We will use established models of low-level human perception, however, we will also exploit psychophysical studies as a main source of knowledge about the way how human observers perceive more complex material surface properties. Our long-term goal is a development of flexible and efficient material sample measurement setup that takes advantage of obtained knowledge about human perception of individual types of real-materials to produce their very accurate but significantly reduced and thus easily applicable digital representation.The focus of this project is very relevant to the airspace / automotive industry and architecture for safety simulations and photorealistic accurate interior / exterior design applications as well as for galleries and museums for accurate digital representation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'LIFE SCIENCE TRACE GAS FACILITY' (TRACEGASFAC) under Sixth Framework.

assistant: **Objectives**

The Life Science Trace Gas Facility operates a variety of unique state-of-the-art trace gas detectors that allow real time measurements at unprecedented detection levels. The strength of the Facility lies in 15 years of experience with applications in Life Science. During the last 5 years access has been given to 63 European users under FP4 and FP5. Access to this Facility, training, and support will be given to researchers from all fields of Life Science.They will carry out trace gas experiments that cannot be performed with conventional instrumentation using the highly sensitive detectors that were developed at the Facility. The strength of these instruments resides in the possibility to perform non-invasive, fast (second time scale) and on-line detection of ultra low gas concentrations under rapidly changing external conditions. The infrastructure is equipped for trace detection of gases of interest in Plant physiology, Post harvest research, Soil science, Microbiology, Ecology, Molecular biology, Medicine, and Human health and proved to be indispensable for these fields of research. Amongst these gases are ethylene, ethane, methane, NO, CO, CO2, water vapour, aldehydes, alcohols, ketones, acids, terpenoids, and many other hydrocarbons, all at or below ppbv level (parts per billion volume = 1: 10E9). Access is given to 5 CO2-laser-, 2 CO-laser-, 1 Quantum cascade laser-, and 1 Optical Parametric Oscillator-based detection systems, next to 2 Proton-transfer-reaction Mass Spectrometer setups.In Europe such a measuring facility is unique and definitely not commonly used by Life Scientists due to the required expertise and high operational costs. We offer access to researchers engaged in experiments where a quantitative change of small gas emissions forms an important as
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Minimal grand unified theory' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

The current paradigm of elementary particle physics, i.e., the so-called Standard Model (SM), has held up superbly under the extensive experimental scrutiny. However, there are reasons to believe that a Grand Unified Theory (GUT) represents more accurate description of electro-weak and strong interactions and elementary particles that participate in them. GUT does not only address some of the conceptual problems of the SM such as anomaly cancellation but it offers possibility to explain various parameters of the SM such as the masses and mixings of elementary particles. And, it can incorporate mechanisms that explain the observed baryonic asymmetry of the universe and the nature of dark matter. Besides a few exceptions, realistic GUT models require a large number of assumptions to be predictive. And, these assumptions often enough outnumber predictions/postdictions.Prime example of the theory that invokes no additional assumptions and that is promising in terms of its testability is the minimal unified SO(10 )" theory (MUST). This theory is super-symmetric and renormalizable with only the 10, 126, anti-126 and 210 representations in the Higgs sector. Due to its appeal and relative simplicity it has been focus of study of various groups. These groups addressed two separate issues. Namely, some of them addressed numerical fitting of fermion masses and mixings while other groups concentrated purely on studies of the viability of Higgs sector and corresponding symmetry breaking patterns. However, there exists no complete self-consistent study that addresses both issues simultaneously. Since there appears to be the tension between the two the proof of model's viability demands unified approach. Thus, the main objective of the project is to achieve first ever-self consistent
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Real-time 3d ultrasound imaging systems with advanced transducer arrays'.

assistant: **Objectives**

Definition of a scanning strategy with the aim of minimizing the number of channels, based on sparse array methods. The goal is to be able to find the best, sparse array layout pattern for a 2000-3000 element array, leading to optimum image quality with respect to the clinical application.Design of electroacoustic structures taking into account specific issues of high density 2d arrays operating at high frequencies.Establishment of key technologies for the transducer array manufacturing: especially controlled microstructuring, high density interconnects and micropackaging techniques.Development of a compact beamformer to support enough channels. Size, consumption and cost reduction will be achieved by scaling and integration of A/D converters and Focusor ASICs, and by tighter integration of analogue front-end electronics with the use of multi-chip modules.Integration of probe and beamformer prototypes. Data acquisition, processing and evaluation using tissue-mimicking phantoms, with respect to image quality.The aim is to lay the foundation for a 3D ultrasound imaging system where the emphasis is on real-time data acquisition and near real-time data visualization. New features of this system are: i) two-dimensionnal transducer arrays using advanced microstructuring and interconnect techniques; ii) compact front-end electronics (beam former) combining rescaled ASICs and multi-chip modules. Prototype probes will be developed and implemented on a down-scaled beamformer prototype. Image quality evaluation will be performed using tissue-mimicking phantoms.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Regeneration and Target Reinnervation after Spinal Cord Injury' in the context of a Seventh Framework call.

assistant: **Objectives**

Recent studies have indicated that combinatorial treatments that target multiple mechanisms are necessary to address the limited regenerative capacity in the adult nervous system. We have shown that chemotropic guidance by growth factor gradients, activation of cell-intrinsic regenerative programs and suitable cellular bridges at a lesion site allow for axons to extend across a lesion site in the injured spinal cord.  Further, regenerated axons form ultrastructurally identified synapses with appropriate target neurons.  However, several challenges that limit the relevance of current approaches remain: Regenerating axons only extend for limited distances beyond the lesion site and axons are not functional possibly due to an insufficient number of synapses or a lack of myelination.The proposed experiments will address these limitations in 3 specific aims. We will examine spatially and temporally controlled expression of neurotrophic factors (NT-3) to enhance the distance of regeneration and target reinnervation by ascending sensory axons after adult spinal cord injury.  We will further define the requirements for persistent target innervation using transient neurotrophin expression and we will examine whether localized degradation of inhibitory extracellular matrix will enhance synapse formation with target neurons.  Finally, we will determine whether Schwann cell and oligodendrocyte precursor cell grafts can re-myelinate regenerating axons and augment functional connectivity and electrophysiological recovery of regenerated axons.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Astrocyte dopamine D1 receptor signaling in depression' (D1-Glia) under Horizon Europe.

assistant: **Objectives**

Major depressive disorders (MDD) represent a global challenge. Although many recent initiatives have resulted in new antipsychotic drugs, their efficacy is not optimal. One possible reason for this is that the prevailing paradigm for drug development is based on the neuron-centric view of how the central nervous system (CNS) copes with diseases. In the fellowship, I will study neuroglia, the nonneuronal cells responsible mainly for maintaining homeostasis in the CNS. Failure in the function of these cells can set the course for neurological conditions, including psychiatric diseases and MDD. Thus, targeting neuroglia has recently been viewed as a new translational ground for drug development. The present proposal is therefore based on our understanding of the potential role of neuroglia in brain disease. One of the major neurotransmitters, dopamine, is known to play an important role in MDD. I will examine the regulation of astrocytes, a major type of neuroglia, by dopamine. Based on the state of the art, I hypothesise that astrocytic dopamine D1 receptor signalling may be involved in the pathophysiology of MDD. Through innovative methodological approaches I will study the regulation of astrocytic D1 receptor signalling at the cellular level in an experimental model of MDD. Moreover, this project will explore D1 signalling in vivo to validate the results obtained on isolated cells. The proposed research will provide a new framework that includes astrocytes and the mechanisms underlying the dopaminergic modulation in depression. This will afford novel cellular targets for treatment of MDD associated with dopamine D1 receptor signalling. In addition, a comprehensive two-way transfer of knowledge is envisioned to bring together competences and experiences necessary for the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Biogeochemistry of erosive material deposition in streams: Impact of particulate deposition upon biofilm carbon cycling' (Bio-ERODS), addressing dissemination and exploitation.

assistant: **Impact**

Inland waterways are an important component of the global carbon cycle, receiving an annual carbon input of ~ 4.8 Pg of carbon per year. Of this approximately 0.6 Pg is buried, entering the lithosphere, whilst 3.3 Pg is recycled through aquatic food webs. These numbers highlight the global importance of streams, rivers lakes and other inland waters but provide little detail regarding the dynamics of organic matter burial and remineralisation. A poorly defined aspect is the relationship between organic matter burial and remineralisation of organo-mineral complexes. Organo-mineral particles form by adsorption of dissolved organic matter to freshly-eroded mineral surfaces, and are thought to greatly control the fluxes of particulate organic carbon at the watershed scale. The unique physico-chemical properties of these particles may enhance their deposition onto and subsequent burial into the sediments of inland waters. However, the metabolic fate of these particles at the water-streambed interface remains poorly studied. Particle deposition at the streambed is enhanced by benthic microbial biofilms. As such, understanding the potential role of organo-mineral complexes in the preservation and burial of organic matter, requires investigation of the interactions with biofilms. Bio-ERODS aims to experimentally investigate biophysical mechanisms driving biofilm-particle interactions and mechanisms that potentially alter the organo-mineral complexation and thus contributing to stream biogeochemistry. Bio-ERODS will thus elucidate, at the fine scale, fundamental mechanisms of the controls on carbon fluxes in streams and rivers.