RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Innovative and efficient solution, based on modular, versatile, smart process units for energy and resource flexibility in highly energy intensive processes' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The project aims to design, develop and validate an innovative solution, the CIRMET solution, to provide energy and resource flexibility to Energy Intensive Industries (EIIs)The CIRMET solution will be validated in an operational environment (TRL7) in an existing process plant (non-ferrous sector) while the replicability of the solution will be assessed in three additional energy intensive sectors (steel, cement and water sector). For this purpose, three new demonstrators will be build up, plus the retrofitting of existing industry process unit. The new demonstrators or modules will be: EFFIMELT furnace, a new concept of flexible and modular process unit for industrial wastes treatment, RECUWASTE heat recovery unit, for flue gas heat recovery and transformation into compressed air to re-used in the same plant, having also the possibility of storing the excess energy and AFF40 (Analytic For Factory 4.0) platform, to improve process plant competitiveness, to increase energy and resource efficiency by controlling and optimizing process units. The retrofitting of an existing process unit (Metallo S.L process furnace) will be done to implement and validate the complete CIRMET solution.A well-balanced consortium formed by academia, research organization, SMEs and energy intensive industries ensures the whole value chain needed to achieve project objectives and paves the way for future exploitation of the solution. The effective dissemination of project outcomes to the current and next generation of citizen and employees through the development of learning resources with flexible usage to be carried out by education/training experts within the consortium is eventually also an important objective of the consortium.


**Keywords:** Energy and resource flexibility, valorization o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Assisting Chinese participation in Converging systems' in the context of a Sixth Framework call.

assistant: **Objectives**

The PARTAKE project aims to instigate long-term research collaboration between leading European and Chinese organisations in the area of Converging systems. The key result of such participation would be the engagement of leading Chinese organisations in standardisation and regulation initiatives that are of strategic importance to the private sector in Europe.The PARTAKE Project plans to achieve its aim by delivering a workshop in Beijing that will begin by presenting the European vision of Converging systems research: Delivering attractive new services exploiting the cooperation of broadcast and telecommunications networks that would be impossible to provide using either network alone. The workshop will then present the results of FP5 projects in Converging systems and report on the progress of the FP6 Integrated Project INSTINCT in Converging systems focussing on their significance for China.Following on from this, Chinese participants will give presentations on the work their organisations would like to undertake in Converging systems. Once the context has been established in this way presentations will be made on the management of European Commission funded projects in Converging systems. Workshop participants representing European organisations active in European Commission funded projects in Converging systems will be available in Beijing for a few days after the workshop to discuss with workshop participants representing Chinese organisations the possibilities for proposals for Commission funded projects involving their organisation and Chinese participation.The Workshop is carefully timed to take place a few months before the proposal submission deadline for the EU-FP6 IST 4th call to give a focus to discussions on preparing project proposals involving Chinese a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Exploring evolutionary links between dwarf galaxy types using distant Local Group late-type dwarfs' (DwarfGalaxies).

assistant: **Innovation**

Dwarf galaxies play a key role in our understanding of galaxy formation and evolution as they are the most numerous kind of galaxies in the Universe and they are also potentially powerful dark matter probes.Our understanding of this galaxy population and of the processes that drive its evolution is limited, mainly because a detailed observational picture of the properties of the various types of dwarf galaxies is lacking.We do not know whether the various types of dwarf galaxies originated from different formation processes, or whether they shared similar progenitors, and environmental effects and/or internal processes caused the observed differences in their properties.In the Local Group we can study in great detail the two main types of dwarf galaxies, those that contain gas (dwarf irregulars, dIs, still forming stars, and transition types, dTs, with no current star formation) and those devoid of gas (dwarf spheroidals, dSphs).This project aims to provide a leap forward in our knowledge of distant dIs and dTs and their relation to the well-studied nearby dSphs. For the first time the wide-area spatial distribution of stellar populations, metallicity and kinematic properties will be derived for stars covering a wide age range in a sample of isolated dIs and dTs. This will be done to a similar degree of detail and using the same tracers as for dSphs.Furthermore, by studying isolated dwarf galaxies, environmental and internal effects as main evolutionary drivers will be disentangled.With the expertise of Prof.Dr.M.Tosi and her group, the applicant will be trained in complementary observational and theoretical approaches; in extracting and modeling star formation and chemical enrichment histories, dark matter mass content and distribution; and exploring the relation betwe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'ROADiBROM (Roadmapping Digital Broadcasting / Mobile Convergence RTD 2015)' (ROADIBROM).

assistant: **Concept**

The ROADiBROM project aims at identifying and characterizing the key Research and Development challenges, required constituency, and the implementation model for a comprehensive European and China joint initiative on holistic and innovative applications of converged digital broadcast and mobile communication in 2015 and beyond. The vision is to transform the Digital Broadcasting/Mobile Convergence landscapes of Europe and China into a coherent community anticipating diversified customer needs and leveraging the potential of the diversity and innovativeness of Digital Broadcasting/Mobile Convergence applications. The project will develop visionary scenarios for Digital Broadcasting/Mobile Convergence 2015 and a detailed roadmap for the implementation process. The roadmap will define measures to take in research, development, demonstration, implementation, dissemination, promotion, assessment, and standardization.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Elucidating how infection shapes neurodegenerative disease at the brain border'.

assistant: **Objectives**

Parkinson’s disease (PD) is the fastest-growing neurodegenerative disease worldwide, characterized by the accumulation of α-synuclein (αSyn). Evidence suggests two potential origins of αSyn pathology: brain-first or body-first initiation, with infection as possible trigger. Epidemiological studies implicate influenza infection in increasing the risk of developing PD, but the precise cellular mechanisms remain unclear. I propose that border-associated macrophages (BAMs), residing at the interface between the brain and periphery, are key to this question.BAMs are pivotal regulators of neuroimmune responses at the brain borders, capable of sensing and responding to peripheral inflammatory cues. During brain viral infections, they promote immune cell recruitment and limit viral spread, while αSyn overexpression induces neuroinflammation, with BAM depletion reducing dopaminergic neurodegeneration.I hypothesize that following influenza infection, BAMs sustain cytokine production and immune cell recruitment, which over time may promote neuroinflammation, αSyn propagation, and neurodegeneration in PD. Specifically, my research objectives are to:1.Characterize the phenotype and function of brain border immune populations in mouse models of brain-first vs body-first PD.2.Determine how BAMs respond to influenza infection and whether this affects neurodegeneration later in life.3.Identify peripheral immune signatures in prodromal PD patients stratified by severe infection, to detect potential populations trafficking to the brain and increasing PD risk.By combining my expertise in viral immunology with Dr. De Schepper’s PD research and Dr. Delputte’s virology expertise, this interdisciplinary project aims to move beyond the current state-of-the-art to elucidate how influenza infecti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'RESEARCH AND INNOVATION FOR  FOSTERING COOPERATION. POLAND EU PRESIDENCY CONFERENCE' (RIconfPL25EU).

assistant: **Concept**

The Polish Presidency of the Council of the EU 2025 (Polish EU Presidency) aims to organize in Warsaw a high-level conference about Central and Eastern European / BIOEAST research and innovation for strengthening green and digital transformation of the agri-food sector, innovative sustainable food systems and bioeconomy development. The event will take place on June 11-12, 2025. This proposal aims to support the organization of the Presidency event on June by financing the costs. The high-level conference will be organized in collaboration with the European Commission, the Standing Committee on Agricultural Research and the BIOEAST Initiative. The event is expected to attract 200-250 participants, including Member States, Members of the European Parliament, experts and interested citizens, including youth representatives, from the R&I community across Europe. Additionally, representatives from the Western Balkans countries, Ukraine and Moldova will participate. Presidency event will be an opportunity to provide knowledge exchange at Member State and EU level on the role of research and innovation in the challenges of green and digital transformation of the agri-food sector and on the scientific and innovative basis for sustainable food systems and the development of the bioeconomy.  The event will be a space for presenting scientific achievements, as well as exchanging practical ideas and innovative solutions. In addition, the event will help further strengthen science policy interface for improved food systems governance, bioeconomy deployment and the green and digital transitions of the agri-food sector. The event will also promote the achievements of Food 2030, Bioeconomy Strategy update, Horizon Europe Partnerships until 2025 as well as the Horizon Europe Mission ""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Provable Security for Physical Cryptography' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Modern cryptographic security definitions do not capture real world adversaries who can attack the algorithm's physical implementation, as they do not take into account so called side-channel attacks where the adversary learns information about the internal state of the cryptosystem during execution, for example by measuring the running time or the power consumption of a smart-card.Current research on side-channels security resembles a cat and mouse game. New attacks are discovered, and then heuristic countermeasures are proposed to prevent this particular new attacks.  This is fundamentally different from the ""provable security"" approach followed by modern cryptography, where one requires that a cryptosystem is proven secure against all adversaries in a broad and well-defined attack scenario. Clearly, this situation is unsatisfactory: what is provable security good for, if ultimately the security of a cryptosystem hinges on some ad-hoc side-channel countermeasure?Despite this, until recently the theory community did not give much attention to this problem as it was believed that side-channels are a practical problem, and theory can only be of limited use to prevent them. But recently results indicate that this view is much too pessimistic.On a high level, the goal of this project is to bring research on side-channels from the realm of engineering and security research to modern cryptography. One aspect of this proposal it to further investigate the framework of leakage-resilience which adapts the methodology of provable security to the physical world.  If a cryptosystem is leakage-resilient, then this implies that its implementation is secure against every side-channel attack, making only some mild (basically minimal) assumptions on the underlying hardware.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Steam generator tube rupture scenarios'.

assistant: **Concept**

The proposed work includes integral and separate effect tests to study fission product retention in steam generator tube rupture sequences. The boundary conditions for the experiments are taken from existent PSA level 2 analysis and by performing additional analysis with integral codes. In the experiments scaled down models of PWR and VVER-440 steam generators and small scale facilities are used. A comprehensive database from the integral and separate effect experimental programmes is utilised in the model development. Models for localisated deposition processes are implemented in codes to analyse the integral experiments. Here also advanced aerosol models implemented in Computational Fluid Dynamics (CFD) environments are used. Finally the model is scaled up for full size steam generators and implemented in system level code(s). Finally the effectiveness of different accident management procedures are assessed.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'A Sensor for Autonomous Navigation in Deep Space' in the context of a Horizon Europe call.

assistant: **Objectives**

The “space revolution” is expected to become the biggest industry in history. During the last decades, space exploration has contributed to the development of various technologies (i.e., GPS, weather predictions, solar cells, reliable power grid, Earth observation services) that feedback into the economy and improve our lives. In 2020, the global space economy was valued at about $ 446.9 B. With the advent of deep-space CubeSats, nanosatellites that disrupted this industry, space agencies are planning to launch tens of CubeSat in deep space per single launch.  The number of deep-space probes is bound to thrive, yet their growth is unsustainable with current practice. Human-in-the-loop operations are particularly relevant for flight-related procedures in cruise phase: the spacecraft position is determined from ground, with a consistent involvement of resources and assets. It is acknowledged that a sustainable deep-space exploration requires enabling self-driving spacecraft.  The SENSE project forges an autonomous navigation sensor for the self-positioning of spacecraft in the solar system. The project stems from the ERC-funded project EXTREMA (ERC-CoG-2019). SENSE aims to elevate the celestial triangulation method conceived in EXTREMA to a proof-of-concept sensor at TRL 4.  Our autonomous navigation sensor, nanoSENSE, is a disruptive innovation that will change the modus operandi for spacecraft navigation. SENSE will revolutionize the way spacecraft travel in space, by cutting the cost of ground control of the whole cruise phase and unlocking the new space mission concept.  The project follows a suitably devised pathway to cover technical validation activities and assessment of exploitation opportunities. SENSE has raised the interest of leading sectoral players (see Let
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Regulation of mammalian genes by new classes of promoter proximal transcription start sites' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

Regulation and fidelity of gene expression is fundamental to the differentiation and maintenance of living organisms. Moreover, understanding how genes are regulated is an essential research question of importance for biomedical application. Although our knowledge about key factors influencing gene expression has increased substantially over the past years, the complexity of gene expression regulation remains elusive. In this project, I intend to discover novel gene expression regulatory circuits operating in mammalian genomes facilitated by pervasive transcription. Although some scattered examples of how pervasive transcription may regulate gene promoter activity exist, no systematic study has been conducted. Here, I will address this question by using a new protein depletion strategy, developed in the host laboratory, to inactivate the nuclear exosome, a major 3’-to-5’ ribonuclease complex, and its co-factors in HeLa and mouse embryonic stem (mES) cells, thus, to create an ideal situation to observe ‘hidden’ cellular transcription events, which would not normally be visible. I intend to assess whether and how this ‘hidden’ transcription contributes to the regulation of promoter activity in HeLa and mES cells, further expanding our knowledge of the regulation of protein-coding genes and ultimately revealing the extent of regulation instigated by pervasive transcription. This study will lay a foundation for future research in the field and at the same time provide novel conceptual information, which might be exploited in prevention or treatment of human diseases.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Self-Amplifying Stereodynamic Catalysts in Enantioselective Catalysis' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Think about an enantioselective catalyst, which can switch its enantioselectivity and which can be imprinted and provides self-amplification by its own chiral reaction product. Think about a catalyst, which can be fine-tuned for efficient stereoselective synthesis of drugs and other materials, e.g. polymers.Highly promising reactions such as enantioselective autocatalysis (Soai reaction) and chiral catalysts undergoing dynamic interconversions, e.g. BIPHEP ligands, are still not understood. Their application is very limited to a few compounds, which opens the field for novel investigations.I propose the development of a smart or switchable chiral ligand undergoing dynamic interconversions. These catalysts will be tuned by their reaction product, and this leads to self-amplification of one of the stereoisomers. I propose a novel fundamental mechanism which has the potential to overcome the limitations of the Soai reaction, exploiting the full potential of enantioselective catalysis.As representatives of enantioselective self-amplifying stereodynamic catalysts a novel class of diazirine based ligands will be developed, their interconversion barrier is tuneable between 80 and 130 kJ/mol. Specifically, following areas will be explored:1. Investigation of the kinetics and thermodynamics of the Soai reaction as a model reaction by analysis of large sets of kinetic data.2. Ligands with diaziridine moieties with flexible structure will be designed and investigated, to control the enantioselectivity.3. Design of a ligand receptor group for product interaction to switch the chirality. Study of self-amplification in enantioselective processes.4. Enantioselective hydrogenations, Diels-Alder reactions, epoxidations and reactions generating multiple stereocenters will be targeted.