RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Planetary stewardship in view of Earth-Space sustainability', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Space-based satellite infrastructures have become indispensable for daily activities on Earth. These opportunities are shaped by an increasing number and variety of actors: from hegemonic rivalry among leading nation states to competition between billionaire companies to build satellite constellations. The rapid expansion of Space activities has led to growing Space debris that challenges the long-term sustainability of the Earths orbit. These developments are furthermore causing global injustice in particular in terms of uneven development as countries grow increasingly reliant on Space infrastructures. Addressing the interrelations of Earth- and Space sustainability is therefore an imminent global challenge.I argue that understanding these rapid developments in Space should be informed by the concept of planetary stewardship, i.e. the ambitions construed by actors to control large-scale system development on Earth and in Space. Spelling out the conditions and mechanisms of sustainable planetary stewardship will enable the formulation of new governance approaches for Earth-Space sustainability.PLANETSTEWARDS will break new ground by theorizing planetary stewardship at the interface of sustainability transitions, economic development, and global governance literatures. I will investigate four main stewardship approaches: state-centric, market-centric, global community-centric, and technocratic approaches. I will i) identify actors value orientations and strategies; ii) analyze processes and mechanisms of stewardship within and across manifold socio-technical systems; and iii) determine possible outcomes of stewardship across different contexts. Based on a comparative, embedded case study design, and combining text-based data from multiple document stocks and interviews,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Bioinspired signal processing for chemical sensor arrays', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

The objective of this project is to develop new computational models for chemical sensor arrays inspired by information processing in the biological olfactory pathway. Particularly, we propose to mimic four processing mechanisms: redundancy, contrast enhancement, associative memory, and mixture segmentation. These computational models will be validated with chemical sensor arrays and their computational complexity explored in order to implement them in portable processing devices (embedded systems, DSP-base d system). This research is of special relevance at this time because of the enormous advance produced in recent years in biological olfaction (2004 Nobel Prize in Medicine/Physiology).The understanding of the olfactory system derived from this advance makes now possible to build computational engines inspired by the architecture of the olfactory pathway. To conduct this research, the background of the researcher in computational models of the olfactory system combined with the ample expertise of the host institution, University of Barcelona, in chemical sensors will be extremely useful. Advanced training activities will be focused on providing the researcher knowledge in chemical sensing devices, instrumentation for chemical sensors and signal and data pro cessing for smart sensing systems.Additionally, the wide European connections of the University of Barcelona through the network of Excellence GOSPEL (NoE, FP6-IST-507610), General Olfaction and Sensing Projects at the European Level) will allow the researcher to collaborate with high quality research groups working in the field. These two factors (advanced training, international collaboration) will significantly facilitate the researcher to acquire a position of professional maturity and independence. Finally, t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Industrial manufacturing of eco-innovative, safe, sustainable functionalised microencapsulated fragrances for fabric softeners' (2014-2020) under Horizon 2020.

assistant: **Objectives**

Fabric softeners are the most popular laundry care products after detergents. They keep clothes soft, enhance nice smells while preventing musty odours, extend the life of clothes, reduce the formation of wrinkles and improve endurance ability of clothes against stains. However, existing fabric softeners are usually inefficient and contain harmful toxic ingredients that are bad for environment and human health. In a laundry cycle, 95% of softeners are lost in water during the draining process, generating excessive impact on the environment. The remaining 5% of softener remains on clothes for only a short time, before slowly releasing the chemical substances on to skin and the environment. CARINSA has developed an eco-friendly polymeric coating that microencapsulates fragrances and drastically improves fabric softener efficiency. The fabric softeners produced with our technology do not contain toxic materials, increase the adherence to fabric in the washing process by up to 10 times and will improve softener duration on clothes by up to 330%. ECO-SOFT project represents a huge opportunity for our company (CARINSA) to commercialise an innovative solution that will benefit the whole fabric softener value chain. Our solution, CARINCAP, allows fabric softener manufacturers to increase their gross margin by 30% while final consumers will benefit from an eco-efficient, safe laundry care product that has reduces cost per wash by 61%. CARINSA has 24 years of experience in the market and is already present in more than 50 countries. We plan to commercialise the technology among fabric softener manufacturers by exploiting our experience in the sector and by using our present channels, which make this project strategically important for the company. Initial market projections sugge
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Theoretical aspects of lattice chiral gauge theories'.

assistant: **Objectives**

This project addresses a fundamental theoretical issue in the formulation of chiral gauge theories on the lattice. The objective is to show that it is possible to maintain gauge-invariance at finite lattice spacing in the overlap formulation of chiral gauge theories on the lattice when the usual (continuum) gauge anomaly cancellation conditions are satisfied. The proposed approach for showing this focuses on global topological aspects of the problem, and has its starting point in the applicants earlier work on topological obstructions to gauge-invariance in the lattice chiral gauge theory. The plan is to extend the classical continuum limit results obtained there to finite (i.e. non-zero) lattice spacing, and then combine this with mathematical results on the topological structure of determinant line bundles to establish the desired result.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Marie curie training site-education and research in molecular biology' (1998-2002) under Fifth Framework.

assistant: **Objectives**

The Warsaw School of Molecular Biology (WSMB) selected as Marie Curie Training Site is opening a call for co-operation in order to complement Ph.D. training courses. WSMB is a part of Institute of Biochemistry and Biophysics of Polish Academy of Sciences (IBB PAS) - Polish leading scientific institution in the field. We offer state-in-art equipped laboratories supported with specialised infrastructure consisting of NMR, Mass Spectrometry, DNA sequencers, and other high-tech facilities. IBB is actively present in international science being selected as Centre of Excellence in Molecular Biotechnology and Polish-French Centre of Plant Biotechnology. Our strong areas of expertise are: Plant Molecular Biology, Yeast and Bacteria Genetics, Genomics, Proteomics, Bioinformatics and Structural Biology. Presently almost 100 students are completing their Ph.D. theses in frame of WSMB. Our students participate in international scientific exchange, publish in renowned journals and present theses written in congress languages. Their credo is to join hard research with pleasure of taking part in breaking frontiers of science. More information you will find on our web site: http://www.ibb.waw.pl.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Resurrecting LUCA - Engineering of RNA-encoded Cellular Life Using Dual Evolution and Intergenomic Transplantation' (RiboLife) under Horizon 2020.

assistant: **Objectives**

Modern cellular life strictly depends on DNA as genetic material. However, a large body of evidence infers the existence of a previous, more primitive biology in which RNA also stored information in cellular entities. Recreating a living cellular fossil representing this transition from an ancient RNA world to modern DNA-based life would fundamentally advance our understanding of our biology’s history, and enable us to explore its biological properties experimentally. However, the reengineering of existing molecular systems into a viable doppelganger of the Last Universal Common Ancestor (LUCA) or one of its precursors is extremely challenging. I propose to use a novel, combined top-down and bottom-up approach to create a modern-day doppelganger of LUCA by engineering bacterial hybrids with core cellular functions encoded on RNA. Using Darwinian Evolution as driver, my team and I will prototype and refine synthetic RNA-replicons through alternating replication in both cell-free and intracellular environments. This “dual evolution” approach will shape increasingly complex RNA networks capable of encoding complex genetic information. Following this, we will use these networks to create information-rich RNA chromosomes, enabling the transfer of essential genomic information from DNA to RNA. Finally, we will address this intergenomic transplantation by combining a novel RNA-delivery strategy with iterative rounds of genome deletion and complementation using state-of-the art CRISPR-Cas9 assisted genome editing.The proposed research will fundamentally advance synthetic biology, and could positively answer the transformative questions: Can we create, program and evolve life-like systems that can survive in both cell-free and intracellular environments? Can we use these entitie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Tracing the global fertility chain- A new political economy of outsourced reproduction' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

In a new kind of post-Fordist niche, called the reproductive bio-economy, organised around the “flow” of reproductive substances and organs, such as egg cells, embryos and wombs, women are increasingly commercialising their bodies by working as oocyte vendors, surrogate mothers or tissue providers. There is fundamental disagreement among scholars and policy makers on how the reproductive bio-economy should be organised. Market critics propose a gift economy based on altruistic donations and informed consent, while market proponents encourage the commercialisation of reproductive tissues and the remuneration of tissue providers. This research addresses and moves beyond the conflicting terms  (gift v. commodity, reproduction v. production, labour v. donation) in which the debate has been framed. It empirically investigates how (bio-)value is created and governed in one particular strand of the “actually existing” reproductive bio-economy, i.e. the global fertility industry,  by exploring the intricate ways in which reproductive tissues and labour move in and out of a commodity state as they move through different regimes of governance. By ethnographically mapping the shifting regimes of labour and property in one specific fertility chain that is becoming increasingly popular, i.e. between Israel/Palestine, South Africa (oocyte vending) and Nepal (surrogacy), the volatile boundaries between gift and commodity, value and waste, labour and donation, property and entitlement will be unpacked. This will be done in an attempt to discern “hidden strategies of resistance” of female reproductive workers in the Global South, and propose alternative and more emancipatory ways of configuring the governance of the reproductive bio-economy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Stepping Up mRNA Mutanome Immunotherapy' in the context of a Horizon 2020 call.

assistant: **Objectives**

Immunotherapy is expected to fundamentally change the treatment of cancer patients. Personalized vaccines elicitingimmune responses against individual cancer mutations have moved into the spotlight. We have pioneered the field andmoved ´cancer mutanome vaccines´ from a mere vision into a disruptive medical concept compatible with currentstandards of drug development and health care practice. Solving key scientific and technological challenges and buildingon extensive preclinical studies, we showed in a first-in-human trial potent tumor-directed immunity in every singlevaccinated patient, and clinical activity of a novel mRNA-based mutanome vaccine. Given that mutations are a hallmarkof cancer, mRNA mutanome vaccines are universal drugs the efficacy of which are unaffected by the cancer type. Theaim of this proposal is to ignite the next wave of advancement by addressing four key constraints challenging a full clinicalrealization of such vaccines. We will address the scarcity of point mutations in many tumors by extending neoepitopediscovery to the full spectrum of genetic aberrations. Cancers are heterogeneous and outgrowth of clones unaccountedfor by the vaccine is an efficient escape mechanism. We will develop neoepitope prediction algorithms deciphering clonalheterogeneity to inform rational vaccine design and countermeasures against selection of target escape variants. Tumorcell resistance to vaccine-induced T cells due to antigen presentation defects will be addressed by developing strategiesfor mobilizing the full repertoire of immune effector mechanisms, including antibodies and NK cells. T-cell exhaustion willbe tackled by vaccination protocols promoting long-lived memory responses and by combination treatments counteractingtumor-mediated immunosuppression. Fina
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Coevolution and self-organization in dynamical networks' under Fifth Framework.

assistant: **Concept**

In this project we want to develop statistical models to describe networks growth and evolution. These models will be based on agents interactions and inspired to the theory of Self-Organization and Fractal Growth. At the same time we are thinking to collect data mainly for Internet and World Wide Web structure in order to validate the models and we want to devise visualization tools in order to analyze large data sets both from numerical simualtions and from real-world data. Application to social andconomic networks will be also considered.DESCRIPTION OF WORK(The study of the dynamics of complex networks requires an interdisciplinary approach that will use methodologies developed in different areas. Complex Systems theory is the natural candidate framework for the study of such networks. It provides a unified language and a set of operative tools to address the fundamental issues involved in the study of such systems. In this framework we want to devise common methodologies for running empirical simulations, computing the relevant quantities on the simulated models and on real samples and visualizing the evolution of networks even on very large dimensions.The unifying feature of these networks is that their global structure and dynamical evolution are the result of locally interacting agents distributed in the system. Shape of the network and agent requests co-evolve to form the final structure. We plan to devise new stochastic models for Internet to be validated through an extensive comparison with a multiview observation from different locations. We also want to devise content sensitive stochastic models of the world Wide Web where documents link to other documents that are relevant for a common subject of interest. The study of such large networks require the develo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'ENHANCE SEISMIC IN THRUST-BELT-AN INNOVATIVE METHODOLOGY FOR SEISMIC ACQUISITION AND PROCESSING IN THRUST-BELT ZONES' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

The aim of the project is to demonstrate that the image of reservoirs in thrust belt environments can be significantly improved using an unconventional and integrated seismic acquisition and processing approach.The improvement in the seismic acquision will be obtained by a new acquisition method allowing simultaneous acquisition of seismic reflections from near to very large offsets and by a new method for the optimal seismic source definition by using vintage data QC indicators and geoeletrical measurements.The improvement of the seismic processing methods will come from the definition of a very accurate shallow velocity model, obtained from the geostatistical integration of different geophysical measurements and their joint processing and from the integration of seismic velocity analysis methods (time and depth velocity analysis, seismic tomography) with the inversion of magnetotelluric data as well as the combined inversion of short and large offset seismic data. Energy technology objectives consist in the definition, through field experimentation, of a reliable and cost effective approach to the seismic exploration of thrust belt reservoirs.The innovative aspects of this project are :- an innovative methodology in the field of automatic and global analysis of field seismic data in shot domain.- an innovative acquisition technique (pluristackable line") allowing the study and optimization of some seismic acquisition parameters such as coverage, source type, offset, during processing.- an innovative acquisition technique ("global offset") allowing to acquire very long offset seismic events simultaneously with traditional acquisition operations.- an innovative acquisition method for seismic source position acquisition optimization, based on the integration of geoelectr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Next generation sepsis diagnosis' (SMARTDIAGNOS) targeting Horizon 2020.

assistant: **Abstract**

Sepsis is a potentially fatal condition that arises when the body’s response to an infection damages its own tissues and organs. It is mainly caused by bacteria and fungi, which spread through the blood circulation. It is one of the biggest public health issue in the EU and worldwide due to its high incidence, mortality, human and economic cost. Early diagnosis is crucial to the management of sepsis, as every hour of delay of appropriate antibiotic therapy increases mortality by 5-10%. Unfortunately, sepsis diagnosis remains one of the greatest clinical challenges in critical care. Current diagnostic methods, including blood culture and different nucleic acid based multiplex technologies, are impaired by the significant time-delay of 1-2 days and/or low sensitivity of 30-50%. Hence there is an urgent need to develop new diagnostic tools that can provide more accurate and earlier sepsis diagnosis, so that patients with sepsis can be administered with rapid and correct initial antimicrobial treatment. The SMARTDIAGNOS project will advance sepsis diagnosis by simplifying clinical sample analysis methods and integrating the currently required numerous steps into a single streamlined device. This will be achieved by combining a number of innovative technologies: 1) 3-dimentional sample concentration to process large amount of raw sample; 2) direct PCR in the 3D microstructure to circumvent DNA extraction step; 3) solid-phase PCR to achieve unlimited multiplexing capability; 4) supercritical angle fluorescence (SAF) microlens array for enhanced fluorescence detection and precise quantification of sepsis-related pathogens. The SMARTDIAGNOS system will go beyond the state of the art for shorter time (1-3 h), higher sensitivity (95%), higher selectivity (99%), multiplexing capab