RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Specific Targeting of Organelles using Peptide-Polymer Vehicles' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

In the past ten years, research in the area of drug delivery has focused on the development of vehicles that can target specific cells in the body and on the development of vehicles that specifically deliver a drug within these cells. Today, science is going one step further and the creation of vehicles that can target specific organelles within the cell is the new challenge. In this project, I aim at creating a new generation of peptide-polymer conjugates that can specifically target the Endoplasmic Reticulum (ER) and/or the Golgi Apparatus (GA) of cells. A direct application for such vehicles is the possibility to deliver antigens into dendritic cells directly in the place where they can bind to the MHC Class I complex. Efficient delivery of antigens to the MHC Class I complex triggers the activation of CD8+ cytotoxic T lymphocytes and is crucial for the creation of novel and more efficient vaccines and adjuvants. The use of polymers for targeted antigen delivery would have many advantages, not the least being an enhanced plasma half-life of the drug, improved solubility and the possibility of controlled release. The success of this will lead to the creation of a novel generation of polymeric-based immunogenics.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Affective neurocognitive model for the ‘Uncanny Valley’' under Horizon 2020.

assistant: **Concept**

The Uncanny Valley hypothesis (UV), proposed already 45 years ago, suggests that too humanlike robots or other artificial characters will elicit feelings of eeriness (Jpn. ‘bukimi’) in human observers. Existing psychological and neuroimaging studies have focused on the humanlikeness dimension of UV but neglected its emotional experience, which was at the heart of the original hypothesis. This interdisciplinary project will develop a thorough model for the emotional dimension of UV, consisting both of subjective verbal descriptions and observed neuronal activation patterns. A series of neuroimaging experiments will be carried out at the Brain and Emotion Laboratory of Maastricht University (UM): the first experiment will test the neuronal correlates of negative emotions elicited by semi-realistic virtual characters, and the second experiment will take a step beyond the original UV hypothesis by comparing the neuronal activation patterns of real and virtual emotional expressions. A self-report questionnaire for verbalizing the emotional experience of UV will be developed during a secondment period at Eindhoven University of Technology (Tu/e). By explicating the emotional experience of UV and by providing open tools for both research and industry, this project will be an important turning point for the future development of all humanlike technologies. Consistently, direct and concrete contacts with the animation industry are planned during the project. My supervisor Prof. de Gelder from UM is one of the thought leaders in the field of affective cognitive neuroscience, and my secondment supervisor Prof. Ijsselsteijn from Tu/e is renowned for his work in human-technology interaction. I am an experienced researcher with a dual background in both of these disciplines, as well
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'An Information-Theoretic Perspective on Massive Asynchronous Connectivity' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

It is expected that in the coming decades the population living in urban areas will increase dramatically.  Therefore, the sustainability of our planet depends critically on a smart and energy-efficient operation of cities. Wireless communication technologies arise as one of the main enablers to reach this goal. For example, services and applications such as intelligent transportation, industry automation, and mobile healthcare will require to accommodate a vast number of heterogeneous and battery-limited wireless devices connecting asynchronously and sporadically to the network. This is commonly known as the massive connectivity problem. Since traditional wireless communication technologies were not designed to support this kind of services and applications, there is a need for a profound theoretical study of this problem.The main objective of MASCOT is to characterize, from an information-theoretic perspective, the fundamental limits and tradeoffs of the asynchronous massive connectivity problem. To this end, I will derive in the outgoing phase at MIT nonasymptotic bounds and asymptotic expansions characterizing these limits. In the return phase at Universidad Carlos III de Madrid, I will then explore different strategies to efficiently and accurately compute the nonasymptotic bounds derived at MIT. During the course of the project, I will elaborate guidelines about how future wireless communication schemes must be designed, and I will adapt existing schemes according to these guidelines. The proposed training activities during the fellowship are fundamental for the correct achievements of MASCOT as well as to secure my future career goals. MASCOT guarantees a two-way transfer of knowledge since it combines my past expertise on elaborating and efficiently evaluating f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Development of a highly efficient electrochemical storage unit for PV systems'.

assistant: **Objectives**

The work described in this proposal aims at the development of a comparatively inexpensive storage battery, the vanadium redox flow battery, which is specially adapted to stand-alone PV-systems requiring seasonal energy storage. The availability of such a battery will significantly reduce the currently high overall system cost. For seasonal energy storage, systems with high capacity are required. Classical secondary batteries, although capable of good energy efficiency in short term applications, suffer from self-discharge, limited system life and high cost. A combination of water electrolysis and fuel cells (hydrogen gas accumulator) suffers from low overall energy efficiency (=36%). Redox flow batteries offer the possibility to design a high capacity storage energy system adapted to the power of a solar home system at high overall energy efficiency (=90%). Furthermore, the cost oi the system is limited, since only the active material and a comparatively inexpensive storage tank is required to provide additional capacity. Fron all possible redox flow batteries, the all vanadium system promises the lowest technical risk in realization. Within the project, suitable materials for high performance electrodes and low cost separators will be investigated. Furthermore, manufacturing technologies for modules and batteries of size up to 5 kW/100 kWh will be developed. Modules and batteries manufactured during the program will be subjected to bench tests and system tests in an existing PV-system. Optimized layouts for solar home systems will be developed as well. The partners are ZSW, Powercell and F.F. Lda, all of which have existing laboratory and testing infrastructures and long-term experience in the field of PV-systems and electrochemical energy storage technologies. ZSW is
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Quantitative Molecular Map of the Neuronal Surface' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The most fundamental roles of nerve cells are the detection of chemical neurotransmitters to generate synaptic potentials; the summation of these potentials to create their output signals; and the consequent release of their own neurotransmitter molecules.  All of these functions require the orchestrated work of hundreds of molecules targeted to specialized regions of the cells.  In nerve cells, more than in any other cell type, a single molecule could fulfill very different functional roles depending on its subcellular location.  For example, dendritic voltage-gated Ca2+ channels play a role in the integration and plasticity of synaptic inputs, whereas the same channels when concentrated in presynaptic active zones are essential for neurotransmitter release.  Thus, the function of a protein in nerve cells cannot be understood from its expression or lack of it, but its precise subcellular location, density and molecular environment needs to be determined.  The major aim of the present proposal is to create a quantitative molecular map of the surface of hippocampal pyramidal cells (PCs).  We will start by examining voltage-gated ion channels due to their pivotal roles in input summation, output generation and neurotransmitter release.  We will apply high resolution quantitative molecular neuroanatomical techniques to reveal their densities in 19 different axo-somato-dendritic plasma membrane compartments of CA1 PCs.  Functional predictions will be generated using detailed, morphologically realistic multicompartmental PC models with experimentally determined ion channel distributions and densities.  Such predictions will be tested by combining in vitro patch-clamp electrophysiology and imaging techniques with correlated light- and electron microscopy.  Our results will pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'intelligent Converged network consolIdating Radio and optical access aRound USer equipment.' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

To meet the high throughput demands envisaged for 5G networks, with increased user densification and bandwidth-hungry applications, while at the same time reducing energy consumption, iCIRRUS proposes an intelligent Cloud-Radio Access Network (C-RAN) that brings together optical fibre technology, low-cost but highly flexible Ethernet networking, wireless resource management for device-to-device (D2D) communication (incl. the use of mm-wave spectrum) and the use of virtual mobiles in the cloud. The iCIRRUS C-RAN introduces the use of Ethernet in the fronthaul/midhaul (for radio signal transport), to minimise cost and make available pluggable and in-device monitoring, and intelligent processing to enable self-optimizing network functions which maximise both network resource utilisation and energy efficiency. To exemplify the attractiveness of the proposition, iCIRRUS focusses on D2D communication in the wireless domain, an important work area in current standardisation, where low latency is known to be a significant factor. The latency and jitter in the iCIRRUS Ethernet-based C-RAN will be an important focus of the research work in the project, with current 5G performance targets in mind; for D2D communications, the task will be to minimise control latency and overhead. A major obstacle for C-RANs is the bit-rate of the digitised radio signals that would be required for 5G – of the order of 100 Gb/s and iCIRRUS will examine the architectural and technological questions surrounding this requirement. Wireless resource management will be investigated, together with mobile device caching and mm-wave D2D mesh networks, to reduce latency as well as load on the infrastructure. Finally, the intelligent network functions in ICIRRUS can interact with mobile cloud processing, and fu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Initial Trajectory Information Sharing'.

assistant: **Objectives**

DIGITS will contribute to reinforce the “Enabling Aviation infrastructure” key feature of SESAR 2020 by demonstrating the ATM benefits that can be realized through the use of downlinked 4D trajectory data in ground systems.The project proposes, in a close to operational environment and in fully representative operational conditions, a set of tightly coordinated development and demonstration actions of key airborne and ground stakeholders in Europe.The airborne industry will develop up to certification the worldwide first airborne unit capable of downlinking ADS-C data according to ATN Baseline 2 standard in compliance with PCP AF#6 (Initial Trajectory Information Sharing).The ANSPs and ground industry will build up pre-operational system platforms capable of receiving and processing ADS-C data including the Extended Projected Profile (EPP). These platforms will e.g. display the shared trajectory data to controllers on their working positions and integrate it in the Flight data Processing systems for the enhancement of the ground Trajectory Prediction.DIGITS plans to have revenue flights becoming available gradually as from mid 2018. These commercial flights will downlink ADS-C data to be processed in ATM ground systems of four participating ANSPs, covering together a substantial part of European airspace and air traffic under a variety of operational conditions. Demonstrations will be done in a shadow mode system set-up, supported by further offline analysis and post-processing. Project partners will make significant efforts to assess together with operational experts the benefits of initial trajectory sharing, its system impacts, potential human performance impacts and opportunities for further ATM performance improvements.DIGITS will bridge the gap between the early v
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Aggression in Children: Unraveling gene-environment interplay to inform Treatment and InterventiON strateg' to be submitted under Seventh Framework.

assistant: **Abstract**

Aggression inflicts a huge personal, psychological and financial burden on affected individuals, their relatives, and society at large. Despite large scientific, preventive, and treatment investments, no decrease in aggressive behavior is seen. This calls for a shift to new approaches. By capitalising on comprehensive longitudinal cohorts, recent advances in genetic, biological, epidemiological, and clinical fields, and combining such interdisciplinary expertise the ACTION consortium will dissect the etiology and pathogenesis of aggression. Based on new insights, ACTION will inform the development of novel diagnostic tools and causative targets and guide the development of treatment and prevention strategies. ACTION is built on interrelated work packages with a focus on a) clinical epidemiology and current classification and treatment problems; b) genetic epidemiology, including Genome Wide Association studies and epigenetics; c) gene-environment correlation and interaction; d) biomarkers and metabolomics. ACTION will deliver an overarching framework that combines a thorough understanding of pathways leading to aggression with a map of current gaps, best practices on clinical, ethical, legal, and social issues. Based on this framework, ACTION will develop novel biomarkers suitable for large-scale applications in children and combine biomarker data with new insights into the effects of gender, age, and comorbidity. ACTION will provide guidance in optimising current intervention programs and deliver new biological targets to pave the way for novel therapeutic interventions. ACTION  will provide a decision tree to guide personalised intervention programmes and will have direct and sustained impact on reducing paediatric aggression. Its overarching aim is to reduce aggressi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'EURO-CHINESE CONFERENCE ON THE INFORMATION SOCIETY' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

The EUROCHINATEL conference will develop information exchanges and industrial cooperation between Europe and China through the promotion of the European industries' know-how in the field of telematics applications. The use of advanced telematics systems for health and education will be demonstrated and commercial, industrial and institutional partnerships between Chinese and European enterprises and institutions will be developed. The conference will contribute to the entry of China in the global information society.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'IMDEA Nanociencia Postdoctoral Training Programme in Nanoscience' (IDEAL).

assistant: **Innovation**

IDEAL is a new fellowship programme promoted by Fundacin IMDEA Nanociencia that over 5 years aims to attract 12 talented postdoctoral researchers to undertake excellent research in any of the scientific areas of research at the Institute:(i) Organic Nanosystems for light harvesting and energy conversion, (ii) Fundamental properties of 2D materials, (iii) Nanomedicine against cancer and infection; (iv) Nanomagnetism and critical raw materials and (v) Solid state Quantum devices for information technologies and the (iv) Technology Transfer Platform.Key objectives:Offer fellows a well-balanced research independence and mentoring from experienced researchers with access to an excellent infrastructure of the highest level for the pursuit of projects in nanoscience and nanotechnology.Provide a full research training and career development programme, with a series of training and career development activities and opportunities. Provide a dynamic research community and a lively international atmosphere focused on interdisciplinary research.Candidates will carry out projects of 30 months choosing a Partner Organization (PO) to develop a secondment (between 2 and 6 months). The candidates have the freedom to choose a PO best suited to their training needs from IMDEAs broad spectrum of collaborators. The intersectoral, international POs (17 have provided letters of support), the majority of which are non-academic, will offer the fellows a chance to build their curriculum, offering experience outside of an academic environment. IMDEA Nano is a non-profit Foundation created in 2006 jointly by the regional government of Madrid and the government of Spain to shorten the distance between research and society; providing new capacity for research, technological development and innovation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Analysis of Free Boundary Problems arising in science', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The aim of this proposal is to investigate several free boundary problems that arise naturally while studying a number of physical phenomena in elasticity, in phase change of materials, in the flow of two liquids in models of jets and cavities as well as in shape optimization. The project consists of four main topics: (1) Stefan-type free boundary problems describing solid-fluid phase transition. The objective is to prove existence and regularity results for those moving-boundary problems in which the moving interface has an active role in the overall process. (2) Thin obstacle type problems describing the behavior of semi-permeable membranes. Mathematically the questions to be investigated include regularity properties of free boundaries and of solutions of systems of equations that model phenomena in elasticity such as the vectorial Signorini problem. (3) Free boundary regularity problems for elliptic measures appearing in optimal design and optimal control problems. The proposed research includes the study of the singular set of the free boundary as well as questions of how the geometry of a domain can be recovered from the regularity of its elliptic measure by applying Geometric Measure Theory techniques. (4) Problems appearing in image processing and optimization problems involving domains with cracks and their origins are present in applications from fracture mechanics. These questions involve the study of the regularity for minimizers for Mumford-Shah type functionals, stability questions of Dirichlet eigenvalues and nonlinear Neumann problems in Reifenberg flat domains.