RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'E-awareness for europe: digital awareness and security for the citizen in europe' (EAWARE).

assistant: **Innovation**

eAWARe addresses the growing need to raise awareness of the security issues relating to information communication technologies at the European level. Given the technological. developments associated with new technologies and the risks posed to information network B, European citizens need to understand the benefits and limitations of such technologies in their day- to-day lives . eAWARe will establish a network of technical , policy and communications special is to devise and implement an awareness raising campaign, spanning all sectors of European society. By addressing this issue, eAWARe supports the calls made by European institutions to launch education and awareness campaigns in this area. Extracting best practice and developing common materials and distribution methods, eAWARe will. add value to existing national initiatives by increasing citizenry trust and confidence, uptake and safer usage of new technologies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Campylobacter control - novel approaches in primary poultry production' (CAMCON).

assistant: **Concept**

CamCon aims to improve the control of Campylobacter in primary poultry production in various parts of Europe and thereby enable the production of “low-risk broilers”. The project places great emphasis on ensuring rapid and effective dissemination of scientific achievements to end-users, in particular the EU poultry industry. The consortium consists of 10 participants from seven countries representing various parts of Europe. The participating institutions include national diagnostic laboratories, institutions providing research and advisory services and universities. The scientists involved have a strong background in Campylobacter research and have published many original publications in the field. CamCon will be a 4-year project with a total budget of €4.17 million where the scientific work is organized in five Work Packages: • WP1 will study the epidemiology of Campylobacter in broilers in selected regions and climates of the EU and compare the sub-types found in chickens; • WP2 will investigate the effectiveness and efficacy of pre-harvest interventions; • WP3 will implement on-site, telecommunication-based, hands-free detection methods and develop quantitative screening methods; • WP4 will develop “second-generation” farm-to-fork contamination models for more precise quantitative risk assessments; and • WP5 will prepare guidelines, educational videos, Internet-based tools, and propose EU standards for producers, regulators and consumers, which are based on the results of the research carried out in the other Work Packages.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Computer-Aided Design of Ionic Liquids as Active Pharmaceutical Ingredients' under Horizon Europe.

assistant: **Concept**

The drug discovery and development process is lengthy, costly, and fraught with high risks, often leading to a low success rate for new chemical entities (NCEs) from discovery through to market approval. A major challenge in advancing many NCEs is their poor bioavailability, primarily dictated by solubility and dissolution rates. Additionally, the solid-state nature of many drugs introduces the risk of polymorphism, which can adversely affect both development costs and therapeutic efficacy. An innovative solution to these challenges is the transformation of solid-state active pharmaceutical ingredients (APIs) into liquid salt forms, known as ionic liquids (API-ILs). While API-ILs show great promise for improving bioavailability and mitigating polymorphism, current design approaches are heavily reliant on expert guidelines and checklists, which limits exploration to a narrow chemical space. To overcome these limitations, the CADAPIL project proposes developing novel models for the computer-aided design (CAD) of API-ILs, resulting in a software package, openAPI-ILDesign, that will enable comprehensive exploration of the chemical space of API-ILs. These models and the corresponding software aim to identify new formulations with optimal thermodynamic and physicochemical properties, addressing the bioavailability challenges of NCEs and revolutionizing the design of next-generation drug formulations.


**Keywords:** Computer-aided Molecular Design,  Thermodynamics of Charged Fluids,  Active Pharmaceutical Ingredients Ionic Liquids,  Statistical Association Fluid Theory,  Mixed-Integer Nonlinear Programming
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Evidence Management for Continuous Certification as a Service in the Cloud', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Cloud-based services have grown from basic computing services to complex ecosystems, comprising (virtual) infrastructure, business processes and application code. These advanced services also increasingly leverage the usage of Artificial Intelligence, including Machine Learning or Natural Language Processing techniques, raising the complexity even higher. Due to the cascade of dependencies among the different products and services, the need arose to bring more agility to the certification process of cloud-based services, e.g., using continuous monitoring and assessment, as evidenced by references to it in the certifications of the EU Cybersecurity Act (EU CSA). To transform the continuous assessment and certification concept into the complete realization of a Certification-as-a-Service (CaaS), several challenges need to be solved: 1) current proposed proofs of concepts for continuous monitoring lack interoperability at technology level, 2) the adoption of cloud and edge computing and the incorporation of regulations on specific topics or domains, such as AI, put significant strain on companies to comply with a multitude of different security schemes, 3) existing market fragmentation for continuous certification (scope, methodologies), hinder transparency and accountability in the provision of European cloud services, 4),smart tools and models need to be adopted to ease the agile application and implementation of the CaaS concept reducing complexity in the whole cloud certification value chain easing the adoption of CaaS by the different stakeholders. To overcome these challenges, the design and implementation of the EMERALD CaaS solution leverages the H2020 project MEDINA’s outcomes and advances them to TRL 7 in the EMERALD core. Two PoCs will be provided; one for compo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Delivering a new, efficient and biobased plant oil and protein extraction system' to be submitted under Horizon 2020.

assistant: **Abstract**

The vegetable oil and related protein sectors use petroleum-based hexane to extract oil from plant materials. Hexane-based extraction is an old technology that is harmful to health and to the environment. Our ambition is to bring a new biobased solvent called EcoXtract® to the market for processing of oil- and protein-rich crops. This will replace hexane in a million tonne/year market leading to transformation of this global agri-food sector. The project will enable us to construct the world’s first large-scale and first small-scale EcoXtract-based oil extraction plants in Europe. This will be followed by world-wide transformation beyond the consortium enabled by our patented solvent technology: EcoXtract.We will use an open innovation approach between five complementary European businesses. Agroprotein is a developer of agri-food plant protein- and oil-based value chains. Pennakem is a global leader in green solvent systems. It developed and now owns the EcoXtract solvent technology. De Wit is a world leader in extracting and marketing high-value oilseed products. NHE is a leader in operating and scaling up extraction systems. An extensive programme of industrial-scale system testing, validation and optimisation followed by product prototying driven by the needs of two value chains lies at the heart of the project. Supported also by co-creative prototyping with clients, we will develop three new mutually supporting business lines within the EcoXtract® framework pioneering global transition of the sector to this new technology. Oilseeds account for about one-fifth of global crop production. This project will revolutionise processing by introducing a biobased alternative to hexane in both low and high volume markets. The commercial-scale optimization of EcoXtract® will b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Identification and characterization of primate-specific duplications and an assessment of intra-specific patterns of selection and copy-number variation' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Segmental Duplications (SDs) can be defined as blocks of DNA ranging from 1-400kb in length with copies found in multiple sites and typically share high sequence similarity (>90%). Studies based in both experimental and computational analyses show that ~5% of the human genome is composed of duplicated sequences. More generally, primate genomes have been found enriched for this complex patterns of interspersed segmental duplications.This 5% of euchromatin differs in structure and content between closely related primates and is not easily resolved by whole-genome shotgun sequence assembly methods.This proposal focuses on this 5% of the genome that historically has been the most difficult for sequence and assembly.The aim of this research is to reconstruct the evolutionary history of all primate segmental duplications in 6 species of primates (Human, Chimpanzee, Orangutan, Gibbon and Macaque and Marmoset) and to understand gene innovations that have emerged within these dynamic genomic regions.   The Main goals of the proposal are: 1.SDs detection and analysis of non-human primate genomes.  2.SDs validation (by means of FISH and CGH arrays hybridizations) 3.Analyze species-specific functional elements and their polymorphism and divergence patterns  The proposed work not only can assist/direct efforts in these regions but serve as a benchmark of the quality of the final sequenced genomes, and, as such, benefit the genomics/evolutionary/genetics community as a whole. The long-term goal is to create an integrated view of the evolution of primate segmental duplications by studying changes in the composition, frequency, size and location at the major branchpoints in the primate phylogeny.  This work has the ancillary benefit that it will provide inssight the origin of SD struct
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'New Materials for Extreme Environments'.

assistant: **Concept**

The goal of this Integrated Project is to provide and to industrialize knowledge-based materials and their compounds for top-end and new applications in extreme environments that are beyond reach with incremental materials development only. The resulting radical multi-sartorial innovations will span-efficiency and lifetime enhancement of energy generation systems; -safe and reusable space components (protection, thrusters); -compact 3-d mustachio devices with optimum thermal management; -long lifetime, low-waste components in new neutron-based systems, e.g. spoliation, ADS, Voters; -and the harnessing of fusion as inexhaustible energy source. To realize these ambitious goals a set of radically new materials capable of withstanding extremely aggressive environments are required. The Project therefore contains four subprojects dedicated to the required extreme fictionalisation of the materials and to the integration of these materials into multi-functional compounds.1.Self-passivating protection materials: (no erosion under oxygen, hydrogen up to 2000°C) 2.E. heat sink materials: (remove heat fluxes of 20 MW/m at up to 1000°C)3.Radiation-resistant materials: (withstand 150 dap at 750°C; low radio activation)4.ExtreMat compounds: (technology for functionalised compounds with very high durability)For the first time this project assembles the critical mass needed for these breakthrough developments by joining the expertise, facilities and forces which are presently scattered into the incremental improvement work for singular applications without connection to the underlying needs and common materials science issues. Besides the creation of the necessary know-how, knowledge dissemination among the partners involved and the potential user community is the common denominator, t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Engineering Combined Sensing and Telecommunications ​Architectures for Tectonic and Infrastructure Characterisation.' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

The 5+ Bn km of currently installed data communications optical fibre cable provides an opportunity to create a globe-spanning network of fibre sensors, without laying any new fibres. These traverse the seas and oceans, where conventional sensors are practically non-extent, and major infrastructures, offering potential for smart structural health monitoring.ECSTATIC will develop novel interferometry and polarisation-based sensing approaches for vibration and acoustic fibre-optic sensing technologies. New possibilities will be defined for sensitivity, distance range and localization, offering a range of solutions for different use cases, while ensuring the coexistence of the sensing signal with live data traffic.A new compact photonic chip-based dual-microcomb engine will enable enhanced range, resolution, and bandwidth of distributed acoustic sensing together with fundamental new knowledge on the physics of physical stimuli in relation to state-of-polarisation sensing. Simultaneous interrogation of multiple transmitted comb lines in the microwave domain with multi-wavelength interferometry and novel state-of-polarisation millisecond field programmable gate array-based transceivers will be developed and characterised to improve the sensitivity, spatial resolution, and dynamic range of distributed fiber sensors.To address the limited data storage and processing capabilities of communication networks new digital signal processing algorithms based on edge devices and artificial intelligence/machine learning will be developed and used to extract information via data-compression techniques. Solutions will aim to minimise algorithm complexity while realising real-time sensing of events and network condition with high classification accuracy.These technologies and algorithms wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'A theoretical and experimental study of bond activation by gas-phase complexation of amino acids with metal cations' (1994-1998).

assistant: **Concept**

Objectives:  1) Determination in polydentate amino acids of highest activation cente reactivity tc metal cations.  2) Accurate determination of binding energies.  3) Structural analysis of ion-amino acid complexes formed with comparative study of differences created by cation nature.  We propose important amino acids (serine, cisteine, lysine) present in cellular exchanges, with the peculiarity of having amino and acid groups and a third functional group that can be attacked by the ion. We shall study reactions with alkaline cations present in this media (Li+, Na+, K+) and will extend to transition metal cations (Fe+, Co+, Ni+) which besides adduct complexation also present insertion and elimination reactions, and other (Cu+, Ag+, Au+) that present dissociative mechanisms.  The project will be carried out from both experimental (using mass spectroscopy with magnetic quadrupolar section) and theoretical points of view, by using ab-initio methods with density functional theory and multiconfigurational methods when needed.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Improved Coherence Fast Swept Source Lasers for Optical Imaging Applications' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Optical coherence tomography (OCT) is an exciting new technique capable of high-resolution, three-dimensional imaging to depths of a few millimeters. The technology has unique advantages as non-invasive, being an imaging method for a variety of imaging applications such as medical diagnostics and industrial testing in manufacturing lines. The tunable laser sources used in OCT are required to have wide spectral range (to improve resolution), fast tuning speeds (to improve imaging times) and narrow instantaneous linewidth (to enhance imaged depth). The preferred wavelength for OCT is 850nm due to better resolution and less attenuation at this wavelength and compatibility with cheap Si detection, but have been hampered by the quality of the laser sources for this region and have tended instead to be developed at the telecom wavelengths of 1300nm and 1550nm. To meet the need for fast speed imaging of deeper structures, we will 1) investigate novel approaches to reach mode-hop free operation for swept sources at 1550nm and 2) develop an optical source around 850nm with a wide band (>70nm), high sweep rate (1MHz) and narrow instantaneous linewidth due to mode-hop free operation. The ICOFAS project targets (a) the training of a young researcher in the field of photonic devices, optical imaging and research commercialisation; (b) the development of novel optical sources with advanced coherence properties and fast sweeping rate; and (c) the industrial validation and commercialising of the developed technology. The training program for the researcher includes new skills in the design and fabrication of multi-section semiconductor fast sweeping lasers, characterisation and optimisation of the laser performance, and implementation of the advanced sources to optical imaging systems.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Circuit mechanisms for behavioral choice from complete CNS activity and connectivity maps' (BICE).

assistant: **Innovation**

Behavioral choice is essential for an animal's survival, but the underlying neuronal mechanisms are poorly understood. A main obstacle is that the circuits involve many brain regions. Hence investigation necessitates the study of whole-brain connectivity and dynamics. Although the connectome structurally links all potential circuits, it is insufficient for constraining functional models and must be complemented by neuronal recordings during behavioral tasks. Furthermore to test models it is necessary to manipulate identified circuit elements. Recent advances in microscopy facilitate the acquisition of complete connectomes for small animals and support neuronal activity monitoring across entire brains. The challenge remains to directly combine these techniques in the same organism. We have developed a method for observing and identifying neurons with interesting activity patterns, whereby the same sample undergoes whole-brain functional imaging and subsequent electron microscopy imaging. We propose utilizing this approach to study the neuronal mechanisms of behavioral choice in Drosophila melanogaster larvae, an ideal model system for this work. We developed a paradigm to study the choice between one of five possible exclusive actions that occur in response to the same stimulus. The aim is to identify circuit mechanisms that promote one action while suppressing all others. Based on function, structure, and neurotransmitters, we will develop models for these competing circuit motifs. Specifically, we will correlate neuronal activity with each action and combine this information with connectomic data. We assume that the competing circuits interact by inhibition, which were described before in literature. These will be tested by genetic manipulation of specific circuit elem