RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Low Emissions Intensity Lime and Cement', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

LEILAC, Low Emissions Intensity Lime And Cement, will successfully pilot a breakthrough technology that will enable both Europe’s cement and lime industries to reduce their emissions dramatically while retaining, or even increasing, international competitiveness. LEILAC will develop, build and operate a 240 tonne per day pilot plant demonstrating Direct Separation calcining technology which will capture over 95% of the process CO2 emissions (which is 60 % of total CO2 emissions) from both industries without significant energy or capital penalty.Direct Separation technology uses indirect heating in which the process CO2 and furnace combustion gases do not mix, resulting in the simple capture of high quality CO2. This innovation requires minimal changes to the conventional processes for cement, replacing the calciner in the Preheater-Calciner Tower. For lime there is no product contamination from the combustion gas. The technology can be used with alternative fuels and other capture technologies to achieve negative CO2 emissions. The project will also enable research into novel building materials with a reduced CO2 footprint, as well the upgrade of low value limestone fines and dust to high value lime applications.The high potential of the project is complemented by high deliverability. The requested grant will secure €8.8m of in-kind funding and support from the LEILAC consortium members, which include world leading engineering, cement, lime and R&D organisations. To accelerate further development, LEILAC will deliver a techno-economic roadmap, and comprehensive knowledge sharing activities including a visitor centre at the pilot site near Brussels. In order to reach the required 80% emissions reductions by 2050, CCS will need to be applied to 85% of European clinker pro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Intestine-on-a-chip for investigating microbioal-epithelail interaction'.

assistant: **Concept**

The small intestine forms a barrier that protects us against the outer world. Here commensal bacteria are tolerated while pathogens are effectively fought off. Occasionally, however, pathogenic bacteria colonize the intestine causing different diseases, which constitute a huge burden worldwide. The ability to study interactions of pathogenic bacteria with the intestine will provide new insights into the disease mechanisms, and new therapeutic targets and ways to prevent disease occurrence. Current animal and 2D models based on tumor cell lines both have shortcomings as they react differently to pathogenic bacteria when compared to healthy human tissues.Primary intestinal epithelial cells can now be cultured as intestinal mini-guts, 3D mini organs. This has partly overcome some of these shortcomings with mouse models and tumor cell lines. These mini-guts are, however, challenged topologically as the intestinal lumen is facing towards the inside of the structures. This makes it difficult to access the luminal surface and study microbial interactions with the epithelium. Furthermore, the static culture conditions do not mimic the in vivo conditions closely enough.I will use microfluidics and microengineering to develop an intestine-on-a-chip device based on primary human intestinal epithelial cells expanded as mini-guts but assayed on mimics of the natural villi structures found in the small intestine. Additionally, the model will allow the fluidic (sheer stress) and mechanic (peristalsis) microenvironment to be closely controlled in order to generate in vivo-like conditions. This is important to study as e.g. Crohn’s disease, that induces suppressed peristalsis, is associated with intestinal inflammation and bacterial overgrowth. Altogether, this intestine-on-a-chip devic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'SOLUTIONS FOR CIRCULAR WATER AND DECENTRALISATION'.

assistant: **Innovation**

SOLUCIR addresses the need for more widespread uptake and deployment of circular and decentralized water management solutions in the face of expanding urban populations and inadequate infrastructure, particularly in peri-urban areas. The project aims to address key challenges across technical, financial, regulatory, and societal domains that hinder widespread adoption of these solutions, that could offer effective alternatives for, but also resilient upgrades to, existing centralized water systems (where available). The project learns from 23 Inspirational Pilots (IPLs) where novel technologies already exist on the ground and leverages insights and lessons learned to develop 5+1 Pathfinding Studies (PFSs) in collaboration with utilities and local stakeholders to demonstrate the effectiveness, scalability, and benefits of decentralized solutions and directly address barriers for large scale deployment. This process is supported by novel tools and methods for integrating decentralized solutions with centralized systems and by enhancing the operations of decentralised systems through digital innovations. Critical to SOLUCIR is the development of comprehensive risk assessment tools encompassing health, operational, and environmental risks, complemented by targeted policy recommendations and societal interventions. SOLUCIR emphasizes financial sustainability, proposing innovative financial mechanisms and circular business models. The project places a strong focus on capacity building and upskilling at key decision levels (utility, local and regional authorities) and ensures the widespread dissemination of its findings and experiences. To realize its ambitions, SOLUCIR unites a strategic alliance of top universities, advanced research institutions, forward-looking water utili
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Stem cells in epithelial cancer initiation and growth' (CANCERSTEM).

assistant: **Concept**

Cancer is the result of a multi-step process requiring the accumulation of mutations in several genes. For most cancers, the target cells of oncogenic mutations are unknown. Adult stem cells (SCs) might be the initial target cells as they self-renew for extended periods of time, providing increased opportunity to accumulate the mutations required for cancer formation. Certain cancers contain cells characteristics of SC with high self-renewal capacities and the ability to reform the parental tumor upon transplantation. However, whether the initial oncogenic mutations arise in normal stem cells or in more differentiated cells that re-acquire stem cell-like properties remains to be determined. The demonstration that SCs are the target cells of the initial transforming events and that cancers contain cells with SC characteristics await the development of tools allowing for the isolation and characterization of normal adult SCs. In most epithelia from which cancers naturally arise, such tools are not yet available. We have recently developed novel methods to specifically mark and isolate multipotent epidermal slow-cycling SCs, making it now possible to determine the role of SC during epithelial cancer formation. In this project, we will use mice epidermis as a model to define the role of SC in epithelial cancer initiation and growth. Specifically, we will determine whether epithelial SCs are the initial target cells of oncogenic mutations during skin cancer formation, whether oncogenic mutations lead preferentially to skin cancer when they arise in SC rather than in more committed cells and whether cancer stem cells contribute to epithelial tumor growth and relapse after therapy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Enginomics in food quality design: the case of shelf-stable fruit-, vegetable- and legume-based foods' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The overarching objective of FOODENGINE is to provide, for the first time, a research-based training programme to a new generation of young food scientists and technologists by introducing an enginomics approach in food quality design. It connects an omics approach to instrumentally quantify food quality with an advanced engineering approach using multi-response kinetics to model food quality changes during processing and storage. At the same time, FOODENGINE will develop models linking the enginomics-based instrumental food quality design with sensory properties, consumer acceptability and consumer preferences to create new products appealing to consumers. FOODENGINE provides unique interdisciplinary, international and intersectoral training opportunities to 13 ESRs, each for 36 months. This extensive international (5 countries), intersectoral (2 universities, 1 research institute and 6 food (ingredient) companies) and interdisciplinary (food engineering, food chemistry, food nutrition and sensory/consumer research) training should lead for all ESRs to a PhD degree. FOODENGINE will boost the career perspectives of the FOODENGINE fellows to the top level. In addition, it has the ambition to become a best-practise example for structuring PhD research training in food science and technology at the European level. Although FOODENGINE specifically focusses on sustainable commodities which are essential parts of a healthy lifestyle (fruit-, vegetable-, legume-based food ingredients and foods), the skills and new ways of thinking the fellows will acquire are generic and can be extrapolated beyond the specific application area (diverse range of food systems or food processes) in their future careers.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Transcending the Boundaries of Holography' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

In this project, I will develop new and timely methods for studying gravity in asymptotically flat spacetime and in the region near black hole singularities, along with their possible holographic interpretations. The thermodynamics associated to black hole event horizons suggests a holographic description in terms of a quantum theory without gravity in fewer dimensions. From string theory, such holographic dualities have been constructed and were tested to amazing precision, but all currently-known examples rely crucially on a negative cosmological constant, which prevents us from using them to make predictions for black holes in our universe. On the other hand, approximating gravity near spacelike singularities has long been known to lead to rich and chaotic dynamics, which therefore appears to be a fundamental property of black holes. However, its relation to known holographic descriptions of black holes is still mysterious.Very recently, I established a new and systematic method of approximating gravity near singularities using dynamical Carroll geometry. By implementing the ultra-local limit of such approximations off shell, my method leads to tractable models in settings previously only accessible with supercomputer simulations, including spatial inhomogeneity and subleading corrections. It is also connected to several recent developments identifying near-singularity chaotic dynamics in AdS/CFT holography. Additionally, using related techniques, I will work towards more realistic holographic models with zero cosmological constant. Here, I will address key roadblocks by establishing how asymptotically flat spacetime metrics are determined by a general null boundary metric, energy-momentum tensor and radiation, which will also allow me to derive consistent ways of qu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The BV Construction: a Geometric Approach' (BVCGA) targeting Horizon 2020.

assistant: **Abstract**

The BRST (Becchi-Rouet-Stora-Tyutin) cohomology plays a very important role in facing the problem of quantizing non-abelian gauge theories via the path integral approach. Indeed, this quantization procedure fails when applied to gauge theories, due to the presence of local symmetries in the action. This problem is overcome by introducing extra (non-physical) fields, defining a so-called BRST cohomology complex. It is precisely this cohomology that allows the recovery of important information on the theory, such as its set of observables or its renormalizability. Despite of its relevance in the context of quantum fields theory, this cohomology still deserves to be fully understood from a mathematical/geometrical point of view. As I discovered in my PhD thesis, a very promising approach to reach this goal is to try to insert the BRST cohomology (constructed following the Batalin-Vilkovisky (BV) approach) in the framework given by Noncommutative Geometry (NCG). In this project I will continue along this line of research by focusing on the case of finite-dimensional gauge theories. Indeed, this context has shown to be surprisingly rich for the analysis of the BV formalism, due to the emergence of a peculiar phenomenon, not appearing in the infinite-dimensional case: the infinite ghosts-for-ghosts. Even though since the discovery of NCG it is known its strong connection with gauge theories, the idea of using NCG as a mathematical framework to formalize the BV construction and the BRST cohomology is still an unexplored territory. The credibility of this approach has been proved by some preliminary results I obtained for U(2)-gauge theories. Moreover, since NCG gives a common tool (the notion of spectral triple) to study both finite and infinite-dimensional gauge theories, the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Multifunctional Satellite Radiator' (MSR) targeting Horizon 2020.

assistant: **Abstract**

Multifunctional Satellite RadiatorSecuring space assets against man-made space debris present at frequently used orbits became integral part of space mission definition and overall spacecraft design. Radiator panels as part of the outer shell of spacecraft already provide some degree of protection to the instruments behind them. Overall project objective is to develop a new class of multifunctional structural radiators for small and medium satellite missions where high mechanical and thermal performance shall be combined with improved space debris and cosmic radiation protection characteristics.Radiator panels manufactured from aluminum foam sandwich (AFS) are able to fill the gap between conventional honeycomb and integrally milled structural radiators. Due to the lightweight core they offer high stiffness-to-weight ratio like honeycombs while the metallic bond between facesheet and core ensures superior load bearing capability and thermal conductance provided by integrally milled radiators. AFS radiators are capable to provide mechanical support for heavy electronic boxes, offer good thermal performance combined with enhanced radiation and debris protection for the hardware located behind the radiator panel. Main advantages of AFS radiators compared to existing honeycomb based radiators are:• high in plane thermal conductance without heat pipes due to isotropic core structure,• higher insert strength,• better debris protection,• better radiation protection,• originally thick face sheets can be manufactured according to mechanical and thermal needs,• improved outgassing parameters due to lack of adhesives,• easier grounding implementation due to metallic contact between core and face sheet.As the result of this development Europe will be the leader provider of satellit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Bacteria Intrinsically Orchestrated with Designed Enzymes for sinerGistic Rate-Accelerated plastic Degradation Efficiency'.

assistant: **Objectives**

Plastics are one of the most widely used materials, with a wide variety of applications across all sectors of the economy. Its production is estimated to be around 360 million tonnes, and thus synthetic polymer is poorly biodegradable. Plastic life cycle is responsible for greenhouse gas emissions, contributing to climate change, plastic waste has been found in every ecosystem, are broken down into small pieces, microplastics, which can have a negative impact on organisms, and altogether causing an unprecedented ecological crisis. We aim to tackle this problem through Bacteria Intrinsically Orchestrated with Designed Enzymes for sinerGistic Rate-Accelerated plastic Degradation Efficiency (BIO DEGRADE) project, using a novel application of biotechnological-based approaches to synergistically increase the efficiency limits of multi-enzymatic solutions. The project will perform genomic modification of microorganisms with their own evolved collection of computationally-engineered proteins for (micro)plastic degradation. We are not engineering single enzymes to enhance their catalytic activities, as it will computationally design multitude (hundreds) of proteins from the microorganism, and boost them with extra catalytic sites making them into plurizymes. The additional active sites able to degrade plastics will designed into the proteins employing advanced molecular simulation techniques such Protein Energy Landscape Exploration (PELE) together with machine learning methods. In this way, the proteins will not be from other microbial origin (heterologous), but their homologous proteins, to which an extra active-site capable of hydrolysing microplastics will be designed and genetically added, not altering the gene expression pattern of the microorganisms. These organisms will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'A Unified Route to Polycyclic Terpenes' (Route2polyTepr).

assistant: **Innovation**

In this proposal we would like to demonstrate the strategic role that xanthates could play in providing a unified approach to a multitude of polycyclic terpenes and in shortening considerably the synthetic routes. By enabling the strategic intermolecular creation of new carbon-carbon bonds on unactivated alkenes and the formation of rings not readily accessible by other methods, the degenerative radical exchange of xanthates opens numerous synthetic avenues not hitherto available. Unusual retrosynthetic disconnections will now be envisaged, and it is hoped that a unified, short, and practical route to numerous classes of polycyclic terpenes and terpene alkaloids can be implemented. Demonstration of the advantage of using xanthate transfer to the synthesis of polycyclic terpenes will bring the academic’s attention to novel applications of radical reactions, promoting the development in the area.


**Keywords:** Total synthesis, Terpenes, Radical chemistry, Xanthate transfer
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Fuel Cell Testing, Safety, Quality Assurance' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

The compilation of pre-existing, and further development of harmonised, test procedures applicable to fuel cells, stacks, and systems constitute the objectives addressed within FCTESTNET. The subsequent development step is the necessary validation and benchmarking of the findings of FCTESTNET.The currently proposed STREP project is, Fuel Cell Systems Testing, Safety and Quality Assurance (FCTESQA). The proposal especially addresses the aspects of pre-normative research, benchmarking, and validation through round robin testing of harmonised, industry-wide test protocols and testing methodologies. This activity will provide support for the essential pre-normative research efforts towards standardisation, thereby contributing to the early and market-oriented development of specifications and pre-standards. The progress beyond the state-of-the-art is that for the first time within the EU the internationally agreed harmonised test procedures (FCTESTNET results) will be validated through experimental campaigns.Test protocols will undergo benchmarking and round robin testing in different laboratories. FCTESQA results will be discussed, debated and agreed in co-operative progress meetings and dedicated international workshops under the IPHE auspices. In addressing the above-mentioned issues an International consortium from EU and INCO members has been established, based on the FCTESTNET structure.