RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'European network on methodology and application of economic evaluation techniques' (1994-1998).

assistant: **Innovation**

* To review past and current efforts to evaluate health services* To review existing guidelines for economic evaluation of medical services in Europe* To discuss and implement measures for quality insurance of economic evaluation  studies in medical care* To develop guidelines that should be valid throughout the European UnionThere is growing concern in all industrialised countries over the rising costs in medical care. In most European countries there is an extensive debate over how one can contain costs in medical care. The debate extends to the search to develop and apply techniques and processes to select health services which should be paid for by the national health service or social health insurance. In the past few years economists have applied models of cost benefit analysis to medical services. In addition, public health researchers have discussed the question of evaluating health services according to their medical, epidemiological, economic and societal benefits. The outcomes of these economic evaluation studies are necessary, either to set prices, to place pharmaceutical products on positive lists or to influence prescription decisions and to enable registration on the reimbursement schedule of social health service suppliers.It is extremely important for health policy in Europe and the European countries to develop mutual methodologies and standardised techniques in evaluating health services with regard to their economic costs and benefits. The establishment of the European market and the fulfilment of the Maastricht-Treaty requires that health policy in all countries use similar tools, speak the same language" and enable the exchange of information on the economic aspects of health services. Therefore, a group of university-based economists was founded t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Multidisciplinary Adjoint Design Optimisation of Gasturbines' (MADDOG) under Horizon 2020.

assistant: **Objectives**

Adjoint based design optimization techniques are widely recognized as having a large potential to revolutionize the design process of modern gasturbines. By applying such techniques, the optimization of the entire gasturbine system with million degrees of freedom is within reach of the current available computational power. Such simulations include inherently all interactions between the different components avoiding sub-optimal designs. However, today’s reality is far from this prospect. Current adjoint design optimization techniques only consider aerodynamic performance, preventing the optimization of complete systems, as they are by their very nature multidisciplinary. This project will develop an adjoint optimization methodology that goes beyond only aerodynamic considerations and includes other disciplines such as structural mechanics and vibration dynamics concurrently for the first time, such that in the longer term optimization of complete systems will be achievable. The key to achieving a true multidisciplinary adjoint design optimization is to work with a master CAD geometry that is shared between all the different disciplines. This differs significantly from the current practice in adjoint techniques, which mainly considers parameterisations that are suitable for only aerodynamic optimizations. The involvement of a master CAD geometry requires the differentiation of a CAD system, until now this has not been performed as CAD systems are invariably proprietary and as such not accessible. In addition, the extension of the methodology to multiple disciplines requires for a highly skilled researcher with a background in aerodynamics as well as structural mechanics. The fellow of this proposal is a research leader at the Von Karman Institute, which has gained signi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Rational design of novel heterometallic MOFs for their use in heterogeneous catalysis for cascade reactions' (2014-2020).

assistant: **Concept**

The field of metal-organic frameworks (MOFs) is currently among the most extensively studied topics in chemistry given the large number of fascinating applications associated with the chemical versatility of MOFs. In particular, the use of MOFs as heterogeneous catalysts is an area that has attracted considerable attention since, in principle, the ideally suited architectures of MOFs can present catalytically active sites spatially arranged. With the expansion of this area, a new emergent class of heterometallic metal-organic frameworks (hetero-MOFs) has recently been considered for the study of an important type of reactions from an industrial point of view in which two or more individual reactions are carried out in a single step (""tandem"" or ""cascade"" reactions). However, the synthetic approach for the preparation of these hetero-MOFs has been mainly conducted by post-synthetic replacement of ions with the same oxidation state, with lack of control over the final composition.The project herein described focus on the design and preparation of novel hetero-MOFs with enhanced stability to perform as superior heterogeneous catalysts. With this purpose, a reasonable straightforward method is proposed, consisting in the low temperature synthesis of hetero-MOFs using pre-designed heterometallic secondary building units (SBUs) as starting materials. The main challenge lies in the control of the metal stoichiometry based on cations with different oxidation states and therefore very different chemical reactivities. The catalytic performance of the novel hetero-MOF materials will be tested during a secondment of excellence already established in the hetero-MOF project.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'GENE THERAPY FOR INHERITED SEVERE PHOTORECEPTOR DISEASES'.

assistant: **Innovation**

The retina represents the visual sensory receptor of the nervous system (CNS).  Inherited diseases like Retintitis Pigmentosa (RP) and Leber Congenital Amaurosis (LCA), for which no therapies are available, are due to mutations in genes preferentially expressed in the photoreceptor cells of the retina. Vectors derived from the adeno-associated virus (AAV) efficiently transduce the retina of animal models. AAV-mediated gene transfer reverts retinal pigment epithelium (RPE) defects and the safety of this strategy is being tested for the first time in humans by an AAVEYE partner.  However, approaches to correct photoreceptor-specific diseases are inefficient. The objective of the AAVEYE consortium is to develop state-of-the art gene transfer to photoreceptors in the retina, and to provide pre-clinical proof-of-concept of gene therapy for severe blinding retinal photoreceptor diseases to be transferred from bench to bedside.  AAVEYE, which uniquely combines leading European scientists in the fields of: AAV-mediated gene transfer to the retina, elucidation of the pathogenesis of photoreceptor degeneration and design of molecular diagnostics for inherited retinal diseases, will accomplish this through:   1) development of AAV-based long-term and safe  gene transfer to photoreceptors through combinations of endogenous promoters and AAV serotypes. 2) assessment of the impact of AAV-mediated photoreceptor transduction on rescue of visual function in animal models of severe RP and LCA. 3) evaluation of the efficacy of combination of gene replacement with adjuvant molecules on photoreceptor survival. 4) characterization of patients with severe inherited photoreceptor diseases to move from bench to bedside the gene therapies strategies tested. The results of this proposal will prov
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Development of In situ Nitric Oxide Sensor' (DINOS).

assistant: **Innovation**

Nitric oxide (NO) is a critical yet understudied component of the marine nitrogen cycle and atmospheric chemistry, with its concentration, dynamics, and sources in the ocean poorly constrained due to limitations in current measurement methods. Existing techniques often underestimate in situ NO concentrations and fail to capture short-lived events, diurnal cycles, and fine-scale spatial heterogeneity, as NO's high reactivity and short lifetime lead to rapid degradation/loss during sampling. The DINOS project addresses these challenges by developing the first reliable, user-friendly underwater sensor for dissolved NO, offering picomolar (pM) sensitivity and second-scale response. By advancing in situ sensor technology, DINOS minimizes sample loss and handling artifacts, building on the success of WHOI’s ROS instruments (DISCO and SOLARIS). This innovation enables the capture of transient biogeochemical processes, enhancing our understanding of NO’s complex dynamics in marine systems. During the 24-month outgoing phase at Woods Hole Oceanographic Institution (WHOI), the sensor will be developed in collaboration with Dr. Scott Wankel and Dr. Colleen Hansel, leveraging their expertise in ocean sensor design and engineering. The prototype will undergo laboratory testing and calibration at WHOI, followed by field validation. In the 12-month return phase, the sensor will be deployed at the Boknis Eck Time Series Station in Eckernförde Bay (southwestern Baltic Sea), coordinated by Prof. Dr. Hermann Bange at GEOMAR. These advancements will provide unprecedented insights into the role of NO in marine biogeochemical cycles.


**Keywords:** chemical oceanography, marine chemistry, marine biogeochemistry, trace gases, ocean sensor, nitrogen cycle, nutrients, nitric oxide, climate cha
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'BIOLOGICAL AMMONIA REMEDIATION IN LIVESTOCK FARMING'.

assistant: **Concept**

94% of all ammonia emissions in the EU result from agriculture, with livestock responsible for 80%. Ammonia is found in the animals’ excreta and rapidly volatilises to the environment. Atmospheric ammonia (NH3) has great environmental implications due to its important role in ecosystem and global nitrogen cycle, as well as contribution to secondary particle formation. Particulate ammonium species contribute to the degradation of air quality and visibility, as well as to the atmospheric radiative balance. NH3 emissions are also a primary cause of welfare problems in livestock farming. Up to 30% productivity losses have been reported in farms, associated to animals’ disease, mortality and lower quality of the meat or milk.To date, no solutions exist that eliminate NH3 from its source, but only solutions that reduce it once released, not eliminating the problem. We have developed the first solution designed to work directly on the source of NH3 emissions and do it with an efficiency or nearly 100%. Our solution consists of a microbial-enzymatic mix that is applied directly to the manure to accelerate the natural transformation processes. Once NH3 is transformed, its emission stops. The approach is based on enhancing the natural process occurring in the manure. It is 100% natural based and is specific to each farm type, as each animal’s manure differs, ensuring maximum efficiency and minimal dose. The composition has recently been patent granted in Europe and Asia. So far, we have completed development of our solution for bovine and pigs, however, their entry is limited by the absence of a validation form a recognised research institute. We now aim to obtain this validation as well as continue development to extent the formulation to all other types of farms. Our product ha
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'PLANAFFHO - PLANning for AFFordable HOusing' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

PLANAFFHO - PLANning for AFFordable HOusing, aims to examine how land-use planning has contributed to the provision of affordable housing for low-income people and has promoted a mix of housing tenures within new developments in three capital cities - Copenhagen, Lisbon, and London, over the last ten years. The first aim and principal focus of the research is therefore investigating planning and housing activities in three cities (Copenhagen, Lisbon and London) that seek to address problems of housing shortage, affordability, and segregation of housing tenures. The research aims to provide practical knowledge and innovative advice to decision-makers on what can be done regarding these huge societal challenges. The second aim of the research, underpinning and informing the former, is to make a contribution to the theoretical and methodological advancement of international comparative research on housing and land-use planning. In order to meet these aims, the theoretical and methodological skills of the candidate will be strengthened at the Cambridge Centre for Housing and Planning Research, located within the Department of Land Economy, University of Cambridge, and led by Professor Michael Oxley. With over 25 years of experience and a proven track record of providing evidence and analysis to influence and support better policy and practice in several areas, the Centre is well-placed to broaden her practical experience of housing and planning matters, from both an interdisciplinary and a comparative perspective. The research will involve short-term visits to planning departments and non-profit housing associations in Copenhagen, Lisbon, and London, aiming to contribute to a mutual exchange of knowledge. During the visits, the candidate will collect data and conduct fieldw
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'New electrotechnical measurement equipment for the application of reflectometric impulse measurement technique' (RIMT-SYSTEM).

assistant: **Innovation**

The European construction industry is confronted with a major problem concerning the safety of large and massive concrete structures: the unexpected deterioration, due to corrosion, of the steel stressing-tendons used in concrete structures (pre-stressed concrete structures), causing these structures to break or reducing their load carrying capacity. Present non-destructive analysis methods (NDA-methods) to measure defects, damage and degradation (anomaly) of pre-stressed concrete structures due to corrosion have been researched without much success. However with knowledge gained in a successful feasibility project executed by NEBEST B.V. in the Netherlands, a new NDA method to locate and measure corrosion of pre-stressed concrete structures has betn tested: Reflectometric Impulse Measurement Technique (RIMT). The principle of RIMT is as follows. Series of high frequency-low voltage electrical pulses are sent through a steel-stressing tendon in pre-stressed concrete structures at one end of the tendon (anchor). The reflection signals are stored and analysed in a recently developed, complex mathematical model. The impedance variations of the standard characteristics are used to calculate the location of the anomaly. Physical and di-electrical anatomies cause different types of impedance variations, which can be recognised in the reflection signals. Therefore it is also possible to reveal the type of anomaly. The objective of this research project is to execute RTD into new electrotechnical measurement equipment (RlMT-Svstem) for the application of the RIMT technology as a NDA-method to locate and measure corrosion of pre-stressed concrete structures. The new RlMT-System will consist of sensors, hardware and software. With the RlMT-System it will be possible to determine
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Heritage for the future, Science for heritage' (CH4F), addressing dissemination and exploitation.

assistant: **Impact**

The proposal consists in organising a European conference on heritage science entitled 'Heritage for the future / Science for heritage, a European adventure for research and innovation'. It is organised by the Fondation des Sciences du Patrimoine (FSP), in partnership with the French Ministry of Culture and the French National Centre for Scientific Research (CNRS) as part of the French Presidency of the Council of the European Union that will take place during the first semester of 2022.The Conference aims to bring heritage science to the forefront to highlight its diversity and gain recognition of its central role to address major contemporary challenges at national and European level, as well as its articulation with the main European initiatives. In line with this mission, the Conference will illustrate how cultural heritage research can concretely support a more inclusive, innovative, and sustainable Europe (i). It also aims to increase the visibility and promote the efficiency of the various disciplines and ecosystems involved in better identification, understanding, preservation, restoration, and transmission of cultural heritage, may it be tangible, intangible, digital or natural (ii). Finally, it will identify challenges and discuss prospects for heritage science in the face of current societal changes (iii).These objectives will be achieved through an ambitious conference programme and various presentation and discussion formats bringing together different stakeholders involved in the production, valorisation, dissemination, and implementation of heritage science knowledge. The conference will also produce a wide range of outputs that will contribute to spread the content and key messages of the discussions towards a wide European and international audience.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Textile extended enterprise resource management system (TEXTERM)' (TEXTERM).

assistant: **Innovation**

The textile and clothing companies in Europe - within the regions and increasingly also between them - are traditionally cultivating a co-operative management style which is very similar to the Virtually Extended Enterprise paradigm. They are forced to put into practice the concept of Dynamically Networked and Virtual Organizations on the actual state of the art. The Textile EXTended Enterprise Resource Management (TEXTERM) project will provide them with new work organization concepts, with knowledge management methods and with tools for co- operative planning and scheduling of their resources. In particular procedures to generate, to code and to share organisational, procedural and operational knowledge for flexible network configuration and co-ordination will be developed and implemented in existing industrial partnerships. A virtual demonstration center will support the dissemination of the results.During the 36 month project, three typical European Extended Enterprise networks representing three textile networks in Germany, Italy and Spain have been analysed and redesigned. Appropriate methods and technologies to meet with the demands for co-ordination and communication, according to the organisational, procedural and operational knowledge sources existing in the networks, have been designed and developed. After having tested the first system prototypes-developed in close co-operation with industrial partners during the TEXTERM project-the systems have been implemented and integrated to the environment of the industrial networks' information systems. All of the networks by now continue their transformation process to become fully dynamically networked.The benefits measured so far mainly concern-reduction of throughput times (-30%),-reduction of stock levels (-20%),-