RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'TRANSLATIONAL RESEARCH AND PATIENT SAFETY IN EUROPE'.

assistant: **Objectives**

TRANSFoRm will develop rigorous, generic methods for the integration of Primary Care clinical and research activities, to support patient safety and clinical research via:1.\tRich capture of clinical data, including symptoms and signs rather than just a single diagnosis. A generic, dynamic interface, integrated with electronic health records (EHR), will facilitate both diagnostic decision support and identification of patients eligible for research, thus enhancing patient safety.2.\tDistributed interoperability of EHR data and other data sources that maintains provenance, confidentiality and security. This will enable large-scale phenotype-genotype association studies and follow up of trials.3.\tSoftware tools and services to enable use of controlled vocabulary and standardised data elements in clinical research. This will enable integration and reuse of clinical data.Why this is important? Whilst diagnostic error is the commonest cause of litigation in Primary Care, EHR systems do not provide for easy collection of the data required for decision support. At the same time, clinical research is becoming uneconomic due to the costs of recruiting and following study participants, tasks that could be supported by the use of data from EHRs.Who will conduct the work? A multi-disciplinary consortium of ICT and clinical researchers from across Europe. These include experts in ontology, integration, distributed systems, security, data mining, user-facing design, evaluation and clinical research domains. Clinical participants include The European Clinical Research Infrastructures Network (where the systems will be deployed), The European General Practice Research Network, and a major Contract Research Organisation.What is the anticipated impact? Improved patient safety by speedin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Ultrafast dual-comb multidimensional lidar' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Since its inception in 2000, the femtosecond frequency comb has revolutionized the field of optical synthesis and metrology, leading to an expanding range of applications. However, the ideal characteristics of an optical frequency comb are application dependent.The scientific goal of this project is to realize a distance-resolved laser ranging system by combining frequency comb technology operating at high (> 10 GHz) repetition rates with techniques formerly developed for coherent fiber-optic communications. This original synergy shall provide a laser radar instrument (LIDAR) operating at unprecedented speeds (1 MHz refresh rate), capable to retrieve information from a target in multiple dimensions (amplitude, phase and polarization) simultaneously. These advances represent a three orders-of-magnitude improvement with respect to state-of-the-art LIDAR systems.This ambitious project shall be developed at Chalmers University of Technology, Sweden, in the group of Prof. Peter A. Andrekson, a world-recognized expert with long tradition in the field of fiber-optic communications and related applications. This project will help to broaden the candidate’s expertise in non-conventional imaging systems and get hands-on training in fiber-optic communication instrumentation. Most importantly, this project offers a unique opportunity for the candidate to dedicate full-time to scientific research for the first time in ten years. The high-quality scientific skills and complementary competences to be acquired within this project will undoubtedly become a leap forward in the candidate’s professional career.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Hybrid Electric Energy Integrated Cluster concerning Renewable Fuels' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The targeted breakthrough of the HELENIC-REF project refers to the establishment of a new sustainable methodology for the water thermolysis at temperatures below 300oC and the immediate corresponding production of energy or fuels. The method is based on our preliminary experimental evidence of water thermolysis at 286oC in the presence of Fe3O4 nanoporous catalytic thick films, with the sustainable maintenance of the catalyst due to a new reduction method based on Lorentz force electrons generated by a magnetic field in the vicinity of the electric current heating the semiconducting catalyst. The method is used for the production of hydrogen and oxygen, as well as of fuels in the presence of CO2 in order to reduce CO2 to CO or even to hydrocarbons, (like Synthetic Natural Gas – SNG) via methanation.


**Keywords:** Catalysis, ferrites, semiconductors, hydrolysis, water thermolysis, chemical processes, phase transformation, renewable fuels
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Production Logistics and Sustainability Cockpit' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Today, numerous methods, systems, and tools exist to facilitate production management, optimize resource utilization, and process efficiency. However, current ERP (Enterprise Resource Planning) systems, MES (Manufacturing Execution Systems), SCADA, and special-purpose solutions are rarely integrated with each other and typically provide no more than point-to-point interfaces between selected functionalities. These sporadic point-to-point integrations do not fulfil the requirements of today's dynamic markets where enterprises have to quickly judge complex situations, react to unexpected events, and make far-reaching decisions.With the growing focus on sustainability, complexity grows even further as production supervisors have to manage energy and material consumption, carbon footprint, and waste output in addition to classical Key Performance Indicators (KPIs) like process efficiency, asset utilization, quality, scrap rate, and costs.  Efforts to find the optimum for yield, quality, speed, or energy consumption individually often result in local optima, far from the ideal solution. Optimization must start at global bottlenecks within the plant or supply network, which can only be identified if overall process transparency is given. Only a tight integration of all systems will provide the visibility and process integration needed to truly recognize the potentials and optimize intra-logistics processes – be it with respect to yield, quality, energy consumption, or waste.Our vision is to offer to manufacturing communities the Production Logistics and Sustainability Cockpit" (PLANTCockpit) as the central environment for monitoring and control of all intra-logistical processes. The PLANTCockpit will give production supervisors, foremen, and line managers the required visibil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Mathematical Problems in General Relativity' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

This proposal deals with mathematical aspects of the problem of gravitational collapse and the formation of black holes. Analytically speaking, this is the study of the initial value problem for appropriate Einstein-matter systems for asymptotically flat initial data. The central questions in the subject are the celebrated cosmic censorship conjectures of Penrose. In previous work, the author was able to resolve the issue of strong cosmic censorship in the setting of a preliminary model, confirming a heuristic picture that had been the subject of debate in the physics community.   A central goal of the present proposal is the development of a complete theory for gravitational collapse in spherical symmetry, which at the same time takes into account the physics of angular momentum. In view of the constraint of spherical symmetry, angular momentum is simulated through charge. Mathematically, a rigorous formulation is given by the initial value problem in the large for a charged self-gravitating scalar field, i.e. for the Einstein-Maxwell-charged scalar field system.   The study can be divided roughly into three analytically distinct families of problems: the study of the formation of trapped surfaces, the study of the decay of fields on the event horizon (Price's law), and the study of the instability of the Cauchy horizon. In parallel with this model, other self-gravitating systems will be studied, motivated in part by current research interests in the numerical relativity and high energy physics communities. All problems require methods which go well beyond standard techniques of the theory of quasilinear hyperbolic p.d.e.'s in two dimensions. In particular, the interaction between geometric features characteristic of black holes with non-linear wave equations will cert
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Development of a new mechanical method to open section galleries in the ornamental stone sector' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

The extraction, preparation and commercialisation of ornamental stone is one of the sectors in which the European Union is unquestionable the world leader, with 50% of world production. The severe environmental impact and low profirability of these exploitations in Europe implies inevitably a change to underground mining specifically developed for this type of mine. It is intended to develop new technology to provide basic tools which allow for more efficient underground mining of ornamental stone deposits, developing a system to open circular section galleries which could be excavated in every type of material.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Green Fast Ferry - the world’s first 30 knots battery powered Air Supported commuter ferry' under Horizon 2020.

assistant: **Concept**

The Green Fast Ferry (GFF) is a full-electric, high speed passenger craft, which will be the only zero emission ferry on the market to meet performances of high speed diesel commuters: 30 knots (55 km/h) speed, large autonomy (26 km routes in 30 min) and fast recharge at port < 20 min. GFF is based on a the patented technology Air Supported Vessel (ASV), that thanks to a pressurized air cushion underneath the hull, reduces energy consumption of > 40%. GFF is suitable for substitution of existing diesel commuters and introduction in sheltered waters and inland where conventional fast ferries are not allowed due to cost erosions, due to strongly reduce wake wash. GFF has a huge market potential in Emission Control Areas in EU (Baltic and North Sea). Objective of the project is to engineer, validate and demonstrate the GFF with potential customers and prepare it for the commercialization. In particular the prototype, developed within an EC funded European project and already tested in real scale, will be demonstrated through logged endurance tests (> 500 hours of operation) to get the technical documentation and engineer the components and manufacturing. The prototype will be demonstrated to the target stakeholders under real-life conditions through a “roadshow” in Sweden: one existing route and two potential high speed city commuting routes subject to speed restrictions due to wake wash problems. The operation of GFF will result in economical advantage of about 300 k€ per year to alternative diesel ferries, with a pay-back-time of 3 years, even less under financial supports. Each vessel will avoid consumption and emissions corresponding to 500 diesel cars each driving 15.000 km per year. The value chain is covered by the 3 partners, providing the key technologies and know
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Mobility Innovations for a New Dawn in Sustainable (European) Transport Systems'.

assistant: **Concept**

The Mind-sets project (MS) will make a major contribution to our understanding of mobility in Europe:• How to better understand mobility (to better influence and change it)• How to predict the likely future attitudes to, and patterns of, mobility• What forms of mobility policies, products and services will best meet these future mobility needs The project provides a new approach to understanding mobility as part of the overall changing lifestyles of different population groups across Europe. A multi-disciplinary coordination of intelligence provides a strong platform for the reinterpretation of our understanding of the ‘mobility mind-sets’ of Europeans; based on engagement with other leading experts in the field in Europe. The approach will be validated against key behavioural issues facing mobility decision-makers: increasing automation, door to door seamless smart mobility, sustainable and energy efficient fuels and mobility and social inclusion.  This enhanced understanding is developed into decision support guidelines (to be called ‘Mind-sets’) with a ‘Think Tank’ of practising mobility stakeholders (decision-makers, operators, developers and mobility system suppliers) to fine tune the guidelines to directly meet market needs. In turn, this will support decisions, create innovation future mobility policy and assist the design and marketing of new products and services. The project is strongly supported by an active exploitation and dissemination strategy, based on a ‘Mind-Sets Knowledge Centre’. Mind-Sets applies a new approach that brings mainstream sociologists, environmental psychologists, health and lifestyle specialists and economists together with sustainable mobility and travel behaviour specialists, plus experts in social media , technological and ITC trend
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Discovery and functional significance of post-translational N-terminal acetylation' to be submitted under Horizon 2020.

assistant: **Abstract**

In mammalian cells, N-terminal (Nt) acetylation is one of the most abundant protein modifications. It is catalysed by N-terminal acetyltransferases (NATs) and mostly occurs co-translationally. However, in contrast to the defined co-translational NATs, post-translational NATs which have crucial regulatory roles are mostly unexplored. Distinct peptide hormones regulate appetite, metabolism, sexual behaviour and pain, and their biological activity is critically modulated by post-translational Nt-acetylation. However, the identity of the NAT responsible for this modification, ‘HormNat’, is unknown, thus the molecular and physiological ramifications of this regulatory circuit remain elusive. Another example is actin, a key regulator of cell motility and cell division. The actin N-terminus is crucial for actin function and in mammals actin is modified by an unknown post-translational NAT, ‘ActNat’. Hence, the objectives of this project are to identify these human NATs acting post-translationally, and to investigate their molecular mechanisms, regulation and impact.We will identify the novel NATs by a combination of classical and newly developed in-house tools like in vitro acetylation assays, unique bisubstrate analogues, Nt-acetylation specific antibodies, and targeted mass spectrometry. Interestingly, Nt-acetylation is considered irreversible, but there is reason to believe that specific substrates are Nt-deacetylated. Elucidation of post-translational NATs and the reversible nature of Nt-acetylation would represent a new era in the field of protein and peptide regulation and identify key cellular and organismal switches.


**Keywords:** acetylation, acetyltransferase, peptide hormone, cytoskeleton, actin, POMC, NAT
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Translation and Commercialization of a QSOX1-inhibitory Antibody Targeting the Tumor Microenvironment in Breast Cancer', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The high number of cancer cases worldwide points to the large global demand for therapeutics for adenocarcinomas (the majority of lung, breast, and pancreatic cancers). Cancer metastases cause more than 90% of cancer patient deaths. There is thus great need to develop more targeted cancer therapies, as well as therapies that enhance the delivery and penetration of chemotherapies to reduce side effects and increase efficacy. A specific societal need is improved therapies for triple-negative breast cancer (TNBC), to which the targeted therapies developed for other breast cancers are not applicable. TNBC treatment, particularly for women with BRCA1 gene mutations, typically involves aggressive chemotherapy, mastectomy, and radiation treatment, with preventive oophorectomy also recommended. The physical and psychological impact of this regimen on young mothers and their families is unquantifiable, and the risk of relapse imposes continuing psychological stress.We have made a revolutionizing discovery that significantly controlled cancer cell adhesion, cell migration, primary tumor growth, and metastasis. We found that inhibition of the secreted enzyme QSOX1 by a monoclonal antibody inhibitor counteracts extracellular matrix ECM matrix stiffening and prevents tumor cell adhesion and migration. The QSOX1 inhibitor showed an added benefit in controlling primary tumor growth and metastasis when provided together with standard chemotherapy in a TNBC model in mice. The antibody drug we are developing based on these exciting discoveries has great promise for commercialization as a new therapeutic agent for TNBC and for other oncology indications.The goal of the CONQR project is to perform key preclinical experiments and explore market entering opportunities for commercialization o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Global Horizons in Pre-Modern Art', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The horizon is the line that seems to separate earth from sky, the line that divides all visible categories into two categories: those that intersect the earth’s surface and those that do not. The horizon is key to the experience of space; it defines our perspective on the visible world. The GLOBAL HORIZONS project will investigate the historical meanings and functions of the horizon in visual and intellectual cultures of the pre-Modern world on a global scale. Examining how pre-Modern cultures conceived of the horizon opens a crucial line of inquiry into understanding the many different ways in which humans have conceived of the relationship between an invisible cosmos and the visible world. Non-western art history is rarely taught at European institutions although countless important works of Non-Western art are kept in museum collections all across Europe. Including non-western concepts of pictorial space is key to the project, however, for Eurocentric models of art history have generally privileged the rise of the linear perspective. This framing has limited our understanding of the horizon’s complex rhetorical, visual and epistemological roles. The project’s specific question connects a variety of objects and epistemological categories, such as panel painting, manuscript illumination, profane und religious objects, cartography, travel accounts, and cosmological treaties. The applied methodological approaches will range from art history, visual studies and cultural anthropology. They will also draw upon interdisciplinary expertise, such as technologies of art production, history of science and philosophy.  The project thus makes an important contribution to global art history, a highly innovative area in which only very few pre-modern topics have been addressed. It