RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Decompression and fragmentation of andesitic magmas during explosive events at open-vent volcanoes' (DFAM), addressing dissemination and exploitation.

assistant: **Impact**

Some andesitic volcanoes at subduction plate margins experience periods of sub-continuous eruption during years, decades, or centuries (open-vent activity periods). Such long-lived periods typically include outgassing events, extrusion of viscous lava flows and domes, and explosive activity of low to moderate intensity. This background activity can be disrupted by violent explosive events of short duration (violent strombolian to subplinian in style), with potential generation of pyroclastic flows. In populated areas these explosions may be highly hazardous because they take place with little or no warning during ongoing open-vent activity. The conditions of magma transfer and controls on fragmentation associated with both the background explosive phases and the paroxysmal events are poorly constrained. To address these questions we propose to combine (1) morphological studies of particles from tephra fall deposits of background and paroxysmal explosive eruptions of Tungurahua volcano (Ecuador) which have known an open-vent activity period since 1999 with (2) analogue decompression experiments of 3-phase flows. Quantitative analyses of the shape and surface structure of pyroclastic material will be performed using innovative tools for morphological analyses (Malvern Morphologi G3 instrument for the study of the shape, and MeX metrology software for the 3D analysis of the surface roughness). The decompression experiments will be set up using a viscous solution of acetone, gum-rosin and particles to simulate the ascent of an expanding 3-phase flow. The morphology data and the analogue experiments will allow us to decipher the fragmentation mechanisms and to investigate the physical conditions of magma ascent in the conduit to the surface. This work will inform not only ha
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Monitoring fish manufacturing process with Advanced Miniaturised subsystem and radio frequency Apparatus' (MAMA).

assistant: **Concept**

MAMA aims to adapt, introduce and evaluate the leading edge electronic technology of miniaturised subsystem, combined with passive contactless radio frequency identification, into the process of manufacturing, packaging and distribution of refrigerated fish. The subsystem will embed in one single component, using high-density packaging, a thermal sensor and an Application Specific Integrated Circuit as sensor interface and RF transponder. The user will use it to implement quality control by identifying fails in refrigeration-chain preservation and to integrate and store goods' time-temperature profile; the supplier will gain an unique smart subsystem, open to various communication protocols and different sensors interfacing, reusable for many applications. No similar product is now available on the market. Dissemination will be carried out to companies where quality control and temperature preservation are major issues (food, chemical, pharmaceutical), or where joint product ID and sensing are needed.Objectives:MAMA technical objective is to develop and evaluate a miniaturised, low cost battery-free RF data logger to analyse thermal history of refreshed food and to implement an enhanced and reliable product identification. This electronic subsystem will be based on transponder ASIC and High Density Packaging technology.MAMA business objectives are:-To provide the user with the benefits of improved accuracy and efficiency of manufacturing and improved quality control processes, with better tracking of products, and complete, error free reporting on its thermal history, thus meeting regulations and controls in food preservation;- To provide the supplier with a miniaturised, low cost, passive subsystem, equipped with a general purpose communication interface and a thermal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Airspace User support to the development of Network Collaborative Management' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The future ATM system concerns the entire ATM community. ATM is seen as a critical element in the air transport value chain and key to connecting Europe’s regions while making it a global hub for mobility and prosperity. The focus of ATM modernisation needs therefore to reflect a greater focus towards increased efficiency and effectiveness while sustaining or even improving the levels of safety and security. At the same time, it must also recognise the need to provide solutions to address critical capacity bottlenecks. ATM modernisation should continue to look at the flight as a whole, e.g. end to end, within a flow and network context, and not in segmented portions of its trajectory, as is still the case today. With this in mind, the vision will be realised across the entire ATM system, offering improvements at every phase of a flight from early planning to complete execution. This vision is building on the notion of “Trajectory Based Operations” and relies on the provision of Air Navigation Services in support of the execution of the business or mission trajectory - meaning that Airspace Users can fly their preferred trajectories without being constrained by airspace configurations. This vision is enabled by a progressive increase of the level of automation support, the implementation of virtualisation technologies and the use of standardised and interoperable systems.The solutions resulting from SESAR 1 and common projects, as well as further R&D under SESAR 2020, will contribute to the above mentioned improvements and benefits to be realised through the gradual implementation and deployment of the SESAR Target Concept. The SESAR Target Concept aims to achieve high performing ATM by enabling airspace users to fly their optimum trajectories. This concept relies on the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'From Geometry to Motion: inverse modeling of complex mechanical structures'.

assistant: **Concept**

With the considerable advance of automatic image-based capture in Computer Vision and Computer Graphics these latest years, it becomes now affordable to acquire quickly and precisely the full 3D geometry of many mechanical objects featuring intricate shapes. Yet, while more and more geometrical data get collected and shared among the communities, there is currently very little study about how to infer the underlying mechanical properties of the captured objects merely from their geometrical configurations.The GEM challenge consists in developing a non-invasive method for inferring the mechanical properties of complex objects from a minimal set of geometrical poses, in order to predict their dynamics. In contrast to classical inverse reconstruction methods, my proposal is built upon the claim that 1/ the mere geometrical shape of physical objects reveals a lot about their underlying mechanical properties and 2/ this property can be fully leveraged for a wide range of objects featuring rich geometrical configurations, such as slender structures subject to frictional contact (e.g., folded cloth or twined filaments).To achieve this goal, we shall develop an original inverse modeling strategy based upon a/ the design of reduced and high-order discrete models for slender mechanical structures including rods, plates and shells, b/ a compact and well-posed mathematical formulation of our nonsmooth inverse problems, both in the static and dynamic cases, c/ the design of robust and efficient numerical tools for solving such complex problems, and d/ a thorough experimental validation of our methods relying on the most recent capturing tools.In addition to significant advances in fast image-based measurement of diverse mechanical materials stemming from physics, biology, or manufac
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Support for transport approximation, zilina, slovakia' (1998-2002) under Fifth Framework.

assistant: **Objectives**

The director, secretary and advisory board consisting ofeight members head SHORT PROFILE OF CENTREOur CeTra. Divisions: Transport Technical Equipment, Transport Infrastructure, Transport Technology, Modelling and Optimalization of Transport Processes, Information Technologies in Transport, Safety of Transport, Quality and Efficiency of Transport, Environmental, Social and Human Aspects = Total yearly research capacity 566 000 hours.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Additive Manufacturing using Metal Pilot Line' (MANUELA).

assistant: **Innovation**

Metal additive manufacturing (AM) allows, by enabling use of advanced design, production of high added value components, at levels that cannot be reached with conventional manufacturing technique. Still, the AM-based manufacturing sequence implies large amounts of critical steps – design for AM, AM fabrication, post processing, etc. – compared to conventional production sequences. Presently, the key competencies related to these steps are either not fully implemented at industrial level (process quality monitoring) or dispersed geographically with poor connection between different steps.  Relying on two major AM technologies (LPBF: Laser Powder Bed Fusion and EBM Electron Beam Melting), MANUELA aims at deploying an open-access pilot line facility, covering the whole production sequence, to show full potential of metal AM for industrial AM production.At first, careful instrumentation and adaptation of LPBF & EBM machines will allow increased process reliability and speed. Secondly, the pilot line – including the adapted processes – will be deployed. The hardware layer will integrate novel process quality control monitoring and automated post-AM handling and processing. The line will be fed by design/optimization and AM process simulation workshops. Those workshops will collect continuous feedback from the physical parts of the pilot lines, to increase process reliability and robustness.MANUELA relies on a consortium composed of industrial end user’s, suppliers, (material/powder, AM hardware, quality monitoring system, software, automation and post-AM treatment) as well as top research institutes in powder-bed metal-AM, covering full range of AM technology chain for pilot line deployment.The deployed pilot line will be validated for use cases, covering wide span of applic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Comparing and Analyzing Collections of Surfaces'.

assistant: **Objectives**

The proposed research program intends to cover all aspects of the problem of learning and analyzing collections of surfaces and apply the developed methods and algorithms to a wide range of scientific data.The proposal has two parts:In the first part of the proposal, we concentrate on developing the most basic operators comparing automatically pairs of surfaces. Although this problem has receiveda lot of attention in recent years,and significant progress has been made, there is still a great need for algorithms that are both efficient/tractable and come with guaranteesof convergence or accuracy. The main difficulty in most approaches so faris that they work in a huge and non-linear search space to compare surfaces; most algorithms resort to gradient descent from an initial guess, risking to find only local optimal solution.We offer a few research directions to tackle this problem based on the idea of identifying EFFICIENT search spaces that APPROXIMATE the desired optimal correspondence.In the second part of the proposal we propose to make use of the methods developed in the first part to perform global analysis of, or learn, collections of surfaces. Weput special emphasis on ``real-world'' applications and intend to validate our algorithm on a significant collection, including data-sets such as biological anatomic data-sets and computer graphics' benchmark collections of surfaces. We propose to formulate and construct geometric structures on these collections and investigate their domain specific implications.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Mechanisms of human mRNA packaging and export'.

assistant: **Innovation**

The export of mRNA from the nucleus to the cytoplasm is an essential step in eukaryotic gene expression. This process requires that only fully processed mRNAs are exported, while undesirable RNAs are degraded in the nucleus. This selectivity is proposed to be mediated by the packaging of mature mRNA by export factors, protecting mRNA from nuclear degradation and licensing it for export to the cytoplasm. However, this model has not been directly and thoroughly tested. Furthermore, the full range of factors that promote the selective packaging and export of mRNA is not yet known.In this proposal, I propose an interdisciplinary and collaborative project that addresses these two major outstanding topics in gene expression. To address the role of mRNA packaging as a key driver of nuclear export versus degradation, I propose to employ a time-resolved transcriptomics and modeling approach to simultaneously measure nuclear mRNA export and degradation rates, modulating mRNA compaction state with rapid protein degradation. Next, I will employ ORF-tag, a novel genome-wide gain-of-function screening method that will determine the full list of proteins sufficient to drive nuclear mRNA export. I will then characterize promising novel export factors using transcriptomic and biochemical approaches to integrate these proteins into our structural understanding of nuclear mRNA packaging. The diverse methodology of this project, the technical support both within the host labs and the facilities on campus, and the high quality of training resources and supervision available will facilitate my own development as a scientist and prepare me perfectly to establish my own independent research group. Through my relocation from the UK to Austria, I will expand the European RNA biology network, for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Biomimetic model of the cell cytoskeleton: polymer networks cross-linked with DNA strands' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The mechanics of cellular processes are determined by the cytoskeleton, a biopolymer network which spans the cell and provides it with mechanical strength. Cells have the capability to autonomously adapt structure and mechanical properties of their cytoskeletal network to changes in physical properties of the surrounding tissue, for which mechanosensing processes play an important role, allowing cells to sense those changes through their focal adhesions. The active adaptability of cellular mechanics has in part its origin in cytoskeletal protein motors (myosin II). An important part of the effort to elucidate how motor activity controls cell mechanics has focused on the rheology of in vitro actin cross-linked networks.The key to understand the mechanical adaptability of the actin cytoskeleton appears to be the poorly understood interplay between the activity of molecular motors and the mechanical properties, dictated to a large extent by cross-linkers. This proposal aims to fill that gap by adopting a unique experimental approach: a model system based on actin filaments grafted with DNA strands that form cross-links by specific base-pairing. The use of DNA strands as cross-linkers will give me unprecedented control over both strength and compliance of cross-links between actin filaments. A bottom-up approach will allow me to study, combining microscopy and rheology techniques, how cytoskeletal self-organization and mechanical properties depend on cross-linker compliance and motor activity, and to explore the formation of cell-substrate adhesions using a biomimetic model of a mechanosensing cell.This approach will provide for the first time a molecular understanding of cytoskeletal network mechanics, and allow for the development of quantitative theoretical models. My pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Pilot for electronic marketing and trading in European small and medium enterprises' in the context of a Fourth Framework call.

assistant: **Objectives**

PETER will set up a pilot to demonstrate how European SMEs - sellers and customers - as well as banks can benefit from the introduction of electronic marketing and trading facilities, saving time, money and resources of work and material. It will be unique in that all aspects of commerce will be addressed, including advertising, ordering and payment, involving ISDN and the Internet. Within the wide area of electronic commerce, PETER will focus especially on the trading of Intellectual Property Rights (IPR) concerned electronic products, and will have a close relation to the IMPRIMATUR project (ESPRIT no 20676), which seeks to build consensus for a unified copyright management infrastructure for future electronic markets. Therefore, the products traded in PETER will basically consist of software solutions, training courseware, multimedia content and consultancy documents.PETER aims to address the individual and specific needs of SMEs in different industrial sectors by making use of today's technologies and building on today's networks. For this, 24 SMEs will participate in PETER as users. The industrial sectors represented by the partners are basically the information technology, business and management consultancy and multimedia productions. The partners will integrate their respective products into the electronic commerce process of PETER, and three of them will also act as customers. The SMEs will be customers of the respective partners, and may represent all possible kind of industry.After an introducing training on electronic commerce and related IPR issues, the user requirements for electronic commerce will be determined and specified. Based on that analysis, a demonstrator will be designed, customised and set up at the partners' and SMEs' premises. This demonstrat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Mitochondrial diseases: From bedside to genome to bedside' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

The aim of MITOCIRCLE is to optimise efficient and accurate diagnosis throughout the EU and thereby establish best practice for the clinical investigation and management of patients and families with mitochondrial disease. Mitochondrial disorders are often fatal multisystem disorders, associated with abnormalities of the terminal component of mitochondrial energy metabolism, i.e. oxidative phosphorylation (OXPHOS). Defects of the respiratory chain are the biochemical hallmarks of human mitochondrial disease. Because of its dual genetic control, defects in OXPHOS can be due to mutations in either the mitochondrial or nuclear DNA. Although OXPHOS disorders have comon characteristics as a group there is considerable clinical variability among patients, even in those having the same genetic defect. As a result each centre has acces to only relatively small numbers of patients in each disease category, making it difficult for individual centres to develop consensus guidelines for the investigation of mitochondrial diseases. There are currently no clinical or laboratory guidelines for the investigation of suspected mitochondrial disease, resulting in considerable variability in the standard and accuracy of investigation throughout the EU. Developing consensus guidelines with a broad relevance for all suspected patients is a matter of some urgency to ensure rapid and accurate diagnosis of mitochondrial disorders in each member state. This will only be possible through the concerted action of the principal European centres with expertise in both clinical and laboratory aspects. This forms the focus of this proposal - to take advances made in the laboratory back to the clinic and thereby improve the management of patient and families with mitochondrial disease. This will pave th