RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'European Clinical trials in Rare Sarcomas within an integrated translational trial network' to be submitted under Seventh Framework.

assistant: **Abstract**

Sarcomas are rare malignant tumors, with an overall incidence of 6/105/year. Bone and soft tissue connective tissue tumours encompass more than 50 different rare histotypes and more than 150 different molecular subtypes. The incidence of individual rare sarcomas subtypes is often less than 0.5/105/year. Given sarcoma rarity as a group, but even more as individual entities, few prospective clinical trials testing local or systemic treatments have been performed in specific subtypes of sarcomas. Clinical trials in specific histological and molecular subtypes of sarcoma can only be performed through integrated clinical networks, centres of clinical excellence, supported by translational analysis.  The drive for EUROSARC comes from the fact that sarcomas should now receive treatment adapted to histological and molecular subtypes and are ideal models to develop rational oncogene-targeted therapies.  Trials based on selected molecular subtypes should now represent the standard approach to delineate novel treatments in individual disease subsets. They are also potential proof of concepts for first-in-class targeted treatment.  EUROSARC aims at validating 1) novel local and systemic  treatment strategies in localized phase, and 2) innovative targeted therapies in advanced phase based on the scientific understanding of molecular alterations driving the tumours thereby developing paradigm changing clinical research.  The consortium builds on the successful co-ordination of scientific excellence of Conticanet and EuroBoNeT FP6 NoEs, where most partners were involved. The objective will be achieved through the development and conduct of  9 (2“Soft tissues” + 7“Bones”, 9 phase I/II and III) investigator-driven clinical trials in rare histological and molecular subtypes of sarcoma, t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Crime Scene Presumptive Sperm Identification Test for Sexual Assault Evidence and DNA Collection' (Sex-Assault-ID).

assistant: **Concept**

Crime Scene Investigation (CSI) requires technology for a rapid, non-destructive, and accurate detection of a wide variety of evidence including invisible stains of bodily fluids. Particularly crucial is the discrimination of semen in stained evidences from sexual assault cases as those evidences have high odds of containing aggressor DNA.This SME Instrument phase 1 project aims at evaluating the feasibility of a new product: Sex-Assault-ID. This product will address Crime Scene Investigation (CSI) concerns following suspicion of sexual assault. Sex-Assault-ID will be a revealing biochemical reagent for semen stains mapping and will be part of the Crime Scene Technician (CST) tool box. It will come as a dissolving tablet to produce a ready to use sprayable solution. After spraying the solution over suspected materials (fabrics, carpets, sofa, bedding, car seat…) a portable UV lamp will specifically reveal semen presence within 3 minutes. The CST will then be able to sample the stains and send them for DNA profiling. Such a technical product does not exist, and the market is worldwide.AXO Science expertise and know-how will be used to transfer Sex-Assault-ID concept directly from lab to market. Current status of innovation is TRL4 (Technology validated in laboratory).The main task will determine chemical formulation to provide a dry, stable tablet, that:1- Allow specific detection of Prostatic Acid Phosphatase contained in human male semen2- Do not affect DNA and sampling.3- Is compatible with dry tablets routine productionThe performances of the Sex-Assault-ID test will be evaluated. But ultimate outcomes of the phase 1 report will be a ""go/no go"" decision on the launching of a phase 2 project involving end user(s) as partner(s) for CSI evaluation.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'IMPACT TB: Implementing proven community-based active case finding interventions in Vietnam and Nepal'.

assistant: **Innovation**

The aim of this project is to assess the facilitators and barriers to scale-up of two proven active TB case finding and comprehensive patient care models in Vietnam and Nepal as examples of these low and lower-middle income country settings. We will use these data to develop an evidence-based framework for scale-up of implementation by the respective National TB Programs in consultation with relevant stakeholders and governments. This will facilitate programmatic adoption of realistic and optimised active case finding strategies by national TB control programmes.We will compare two alternative implementation strategies in each country appropriate to the local level of current service delivery. For Vietnam, we will compare implementation using salaried employees with volunteer counsellors. For Nepal, we will compare two diagnostic testing strategies as a component of active case finding: traditional  smear microscopy or the novel Xpert Omni molecular testing. We will determine the health economic impact of active case detection under the different models and model the long-term epidemiologic impact and cost-effectiveness.The research seeks to achieve the following objectives:1) Implementation of active case finding with comprehensive patient support in 6 districts of Ho Chi Minh City, Vietnam detecting 1,450 additional cases in 2 years.2) Implementation of active case finding with comprehensive patient support in 4 districts of the Central Development Region of Nepal, detecting 1,050 additional cases in 2 years.3) Health economic evaluation of alternative implementation models in low (Nepal) and middle income (Vietnam) scenarios to inform policy.4) Consultation with policy makers, stakeholders and end-users to evaluate facillatators and barriers to scale-up at health sys
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'New organic based ecological surface conversion treatment for general galvanizing' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Eurozinco SpA in Italy and Procoat S.L. in Spain, have recently identified a market opportunity within home and export markets for increasing the use of painted galvanised parts selling to small end-users and to the do-it-yourself market galvanised parts pre-protected during production and ready to be over-painted, i.e. using: a chromium-free passivation/conversion solution; a treatment not producing vapours or moist dangerous for the working environment; a treatment whose maintenance and the eventual disposal of solutions (exhausts and water rinsing) is easy and at low cost. Based on some promising preliminary results, the objective of this project is to develop for HDG (Hot-Dip Galvanised) steel, a passivation solution formula no-rinse, ecological forming a very thin organic film over the galvanised part and being easily paintable either in the galvanising plant either for field constructions. In other words this treatment: 1. should be a simplification of the surface conversion treatment of galvanised parts before painting; 2 should have an improved paint adhesion toward paints and allow a greater number of paint types to be used; 3. should dramatically reduce the so-called ecological impact and the plant dimensions 4. should be in any case a cost reduction of the conventional processes; should have a better corrosion resistance against white-rust occurring in storage and transportation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Consolidating Research and Policy along the Cognitive Computing Continuum'.

assistant: **Innovation**

The transition from H2020 to HE reflects an ongoing mega-trend in ICT: the convergence of Cloud, Edge, and IoT. This tendency has significant impact in Europe at scientific, technological, socio-economic, and geopolitical levels, as these traditionally separated fields are now converging into a much larger ecosystem now sharing a number of common challenges and key priorities. Upcoming RIAs should integrate and capitalise on ongoing efforts, with a vital aspect for Europe in this whole process being to successfully combine and consolidate the technology priorities defined by EU industry through the “European Alliance for Industrial Data, Edge and Cloud” and the advancements that the IPCEI-CIS will provide in the coming years. This transition and the move of the whole community of EC-funded projects and related initiatives towards a closer cooperation with industry is what the NexusForum.EU project aims to support and facilitate by focusing on consolidating research and policy along the Cognitive Computing Continuum, something crucial to effectively expand what the ongoing CSAs (particularly EUCloudEdgeIoT) are working on, thus providing a clear, consistent vision for future research and innovation topics in this EU strategic area. NexusForum.EU, through its unique consortium, will be able to effectively undertake a number of crucial activities, such as producing annual research roadmaps and policy recommendations; fostering collaboration between industry and academia; creating solid links with the IPCEI-CIS and the “European Alliance for Industrial Data, Edge and Cloud”; collaborating with past and present RIAs in order to promote a diverse EU research and innovation community; identifying relevant issues such skills development gaps; analysing the relationship with cru
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'UPscaling GRaphite Electrochemical ExfoliatioN' (UP-GREEN).

assistant: **Innovation**

The possible utilization of graphene as key component in composites, energy storage and conversion devices is heavily hampered by the limited availability of high-quality graphene materials. The current graphene production methods, such as mechanical exfoliation, chemical vapor deposition and chemical oxidation and exfoliation, suffer from extremely low yield of product, limited scalability or a strong chemical oxidation by which a significant number of defects are irreversibly introduced to the graphene. Thereby, it is highly desirable to develop scalable and green preparation protocols for which the oxidation is reduced to a minimum but the production speed of graphene is still high. During the ERC 2DMATER project, we found that the electrochemical exfoliation of graphite is the ideal approach to serve this demand under optimized conditions. Here in this project, we will further develop a lab-scale equipment and process that will be able to produce high quality graphene powders and dispersions on a scale of 1 kg per day, starting from commercially available graphite sources, like graphite foils, rods and papers. We target at producing bulk graphene with electronic properties outperforming those generated by state-of-the-art wet chemistry protocols - but with reduced number of process steps. Moreover, the technologies gained in this project will be transferred towards cheaper raw materials where we aim for direct production of graphene flakes from unprocessed natural resources in cooperation with our industry partner that owns several high grade graphite deposits in Sweden. Eventually, the efficient upscaling of graphite exfoliation developed in this project will bridge the gap between current lab-scale graphene production methods and industry-relevant scales in the mo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Provision of scientific, technical and administrative management of COST' (COST).

assistant: **Concept**

The ESF, as the implementing agent for COST (an intergovernmental system for cooperation and networking of European nationally funded researchers and research activities) and its Committee of Senior Officials (CSO), will provide the scientific, technical and administrative management of COST.This involves establishing a new, free-standing COST Office on a new site. ESF will also staff the Office and ensure its ongoing operations in support of both COST Actions and the scientific governance of COST, especially its Technical Committees. ESF will be responsible for the receipt of proposals for COST Actions, their scientific assessment and their implementation, support and deepening as approved Actions, together with existing COST Actions already agreed for launching or in operation. As well as supporting the Technical Committees, ESF will implement the first of a series of reviews of COST Domains.During this period, ESF will also be proposing a number of reforms of the COST system, including its governance, in accordance with an independent assessment of COST and its own vision of the system. It will also promote synergy between the Technical Committees of COST and its own scientific committees and with other European groups, including the Framework Programme.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'HORTI-PREDICT: A multi-omics framework for accelerating genetic gain in horticultural crops' (Horti-Predict) targeting Horizon Europe.

assistant: **Abstract**

Horticultural crops face the urgent need for climate adaptation and a shift towards a more sustainable production model. Genetic improvement through conventional breeding is one of the most viable and sustainable solutions yet is hampered by its slow pace. Predictive breeding, and the integration of new omics resources, is on the cutting-edge of breeding science and offers a potential solution to accelerate this process. While effective in major cereal crops, predictive breeding has been underutilised in horticulture. This project will harness this opportunity and develop novel predictive breeding methods by uniquely combining multi-omics data and advanced prediction models to speed up the breeding cycle to increase the rate of genetic improvement. To achieve this the applicant will (1) generate high-quality multi-omics data, (2) develop models incorporating multi-omics data and genotype-by-environment interaction terms in order to increase the predictive ability of the model, (3) validate the models and create haplotype catalogues in order to develop practical breeder-friendly tools. Grapevine and apple are two of the most important horticultural species in Europe and will be explored as use cases in the project, however the methodology and tools developed will also be highly relevant for other crops. Specifically, the project will result in three open-access outcomes (1) An end-to-end framework to produce high-quality omics data, (2) Advanced predictive breeding models, and (3) a deployable breeding tool in the form of a haplotype catalogue. All outcomes contribute to scientific advances in either breeding methodology or improved trait knowledge and collectively work towards increased genetic gain for enhanced adaptation of horticultural crops to future environments.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Long-range electrodynamic INteractions between proteinS' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

LINkS will change the paradigm of the self-organization of the intracellular living matter by demonstrating the existence of Long-range ElectroDynamic Interactions (LEDIs) between proteins. LEDIs may act as a long distance protein-protein attractive mechanism expanding above several hundred of Angströms that could explain the high spatial organization and coordination of biomolecular reactions; responsible for the transmission of information in cells. LEDIs result from condensation phenomenon, characterized by the emerging of the mode of lowest frequency; expected in the TeraHertz (THz) frequency band. However, to date, LEDIs have eluded detection, partly because previous theoretical predictions were incorrect, but also because performing THz spectroscopy in aqueous media is a well-known technological roadblock not yet overcome. LINkS will develop a breakthrough lab-on-chip THz biosensor technology to investigate LEDIs between proteins, from in-vitro to in-vivo. No competing or alternative technology exist yet.To this end, LINkS consortium gathers interdisciplinary expertise including theoretical biophysics, cell biology, nanotechnology and microfluidic engineering. Three academic partners and two SMEs, from four European countries will work in strong collaboration, across the traditional boundaries of their disciplines, to develop a disruptive lab-on-chip THz biosensor able to investigate LEDIs in the real complexity of biological systems. LINkS technology will effectively address proteomic analysis and related markets for the benefit of society as a whole. In the long-term, its ramifications will have significant benefits for drug discovery, biomarker identification and associated personalised therapies, and for understanding the influence of electromagnetic fields on
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Protecting Sensitive Data in the Computing Continuum' in the context of a Horizon 2020 call.

assistant: **Objectives**

Cloud computing is transitioning from a few large data centres to a truly decentralized computing paradigm. Computing resources are increasingly provided near the network edge, in a geographically distributed way, in the form of so-called fog nodes. Data produced in end devices like smartphones, sensors or IoT devices can be stored, processed and analysed across a continuum of compute resources, from end devices via fog nodes to cloud services. This decentralized computing paradigm provides huge benefits in terms of reduced latency, increased processing speed and energy savings, but the protection of sensitive data in such a widely decentralized setting becomes a critical concern.FogProtect delivers new and advanced architectures, technologies, and methodologies for ensuring end-to-end data protection across the computing continuum, from cloud data centres through fog nodes to end devices. The FogProtect solutions are generic and can be used in multiple contexts to support many types of applications and services. FogProtect combines four main technology innovations: (1) secure data container technology for data portability and mobility, (2) data-protection-aware adaptive service and resource management, (3) advanced data protection policy management, (4) dynamic data protection risk management models and tools.Three complementary real-world use cases demonstrate the applicability of FogProtect solutions to multiple contexts and the impact of the project’s novel solutions for data protection: smart cities, smart manufacturing and smart media. FogProtect provides the essential building blocks to empower data protection, supporting resilience, trustworthiness and human-centricity in the Next Generation Internet.FogProtect brings together knowledge and solutions of major Eu