RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'New spectroscopic detection principles for chiral compounds in capillary electrophoretic separations' (1998-2002) under Fifth Framework.

assistant: **Objectives**

The accurate determination of chiral (non-symmetrical) compounds in complex mixtures is becoming increasingly important. For instance, in the world of pharmaceuticals it is well known that one enantiomer can have therapeutic properties, whereas its mirror-image compound may be highly toxic.In recent years, chiral separation methods based on capillary electrophoresis ( CE) have been developed, but appropriate detection systems are currently lacking. We propose to study the applicability of a recently developed phosphorescence technique to improve concentration detection limits. For enantioselective detection we propose to make use of chiral phosphorophores that will be custom-synthesized. Finally, we will build a circular dichroism absorption detector to be combined with chiral separations in CE, both in single-wavelength and in spectrally resolved mode. A well-equipped mechanical, glass and electronics workshop, and an experienced optics technician are available for technical assistance. The work is expected to shed light on the potential of enantiospecific detection in CE for the sensitive and selective determination of chiral compounds, with the main emphasis on measuring one enantiomer in the presence of a large excess of the other, as is needed for enantiomeric purity assessment. At VU-ACAS the fellow will be introduced to novel spectroscopic principles and analytical applications. After a basic training in lasers and optics a CE instrument will be adapted and optimised for sensitive detection. Using the optical expertise acquired during the first year, the fellow will then proceed to construct a CE detection system based on circular dichroism. VU-ACAS participates in the multidisciplinary Laser Centre Vrije Universiteit (an EU large-scale research facility and Mari
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Trial application of voice processing in automated banking services'.

assistant: **Objectives**

The technical objective of this project is concerned with assessing the usability of voice processing software in automated banking using the telephone ('direct banking').The purpose of OVID is to bring together international banking partners and technology providers for a trial application of a European automated telephone banking using voice processing. The specific application will comprise a telephone banking service that allows customers to telephone the automated service and enquire about their bank balance and recent activity on their account, to pay bills and transfer funds. The trial application will allow the banks to assess the levels of increased sales and improved productivity that would be possible from the full software implementation. In addition the trial will support assessment of improvements in the ease of use from such automated services, and finally the problems of cross-border operation. The partners intend to approach the work via a series of controlled usability trials of the software in a realistic banking service with real bank customers. The results will be an assessment of how bank customers are able to use the automated service without training and how to design an optimal user interface dialogue which can accommodate the untrained user. In addition, the results will enable the banks to report on the potential added service benefits from such applications. The expected impact of the trial application will be to make automated banking more user friendly and easier to use since voice is one of the most natural interface modes for public access to any service.At present, the question to be answered by the banks is the extent to which recent leading edge advances in the capabilities of speech recognition and understanding are ready to solve the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Deciphering the molecular mechanism of Eleos, a conserved immune system across the tree of life' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Sensing viral infections and mounting a response is crucial for all domains of life. Many immune mechanisms in higher eukaryotes were thought to be evolutionary innovations, but recent research reveals that some components of the innate immune system have evolved from bacterial genes. Eleos, a novel anti-viral system in prokaryotes, shares similarities with eukaryotic GIMAPs (GTPase immunity-associated proteins), yet their evolutionary history and anti-viral mechanisms remain unknown.ECoToL's objectives are threefold:1.Identify Eleos systems, study their architecture, and determine their distribution in bacteria.2.Explore the molecular mechanism by which bacterial Eleos confers resistance against phages.3.Investigate when and how Eleos was acquired in eukaryotes, assess its distribution, and examine the conservation of the mechanism in eukaryotes.We will analyze large genome datasets to trace Eleos system evolution across different life domains. Additionally, we will identify phages Eleos defends against and the mechanisms by which phages evade this defense. Biochemical, biophysical, and structural biology methods will illuminate the molecular mechanisms in bacterial Eleos. Further genomic analysis and experimental methods will answer whether this mechanism is conserved in higher eukaryotes.ECoToL is a multidisciplinary project pioneering comparative immunology between prokaryotes and eukaryotes. This innovative concept aims to enhance our understanding of immune systems, which is critical for staying ahead of viral threats, improving viral infection treatments, reducing viral resistance, and enhancing global health security.


**Keywords:** Antiviral defense, anti-phage systems
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Water Network Sensors for Widespread Use'.

assistant: **Concept**

Widesens aims to design and develop a prototype analytical drinking water probe and its complementary applications for in-pipe water quality measurement with ideal specifications for a wide deployment. These sensors will be based on microelectronic technologies (ISFET, IDEs and microelectrodes). As a first approach they will measure pH, conductivity, bio-fouling, oxidative reduction potential (ORP) and chlorine. Also special mechanics and electronics will be fabricated to achieve self-calibration and maintenance procedures, long lifetimes and remote monitoring. Finally, leak-detection will also be enabled through pressure sensors.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'European carotid stenting network (ECSN)' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Stroke is a major cause of disability in the ageing population. Atherosclerotic carotid artery stenos is an important cause of stroke, which can be prevented by carotid endarterectomy. However, endarterectomy requires an incision in the neck and carries a small risk of operative stroke. Stinting, a new end vascular method of treating carotid stenos is, avoids some of the discomforts and complications of surgery. However, stinting also risks procedural stroke and may have unacceptable incidence of rest enosis. Evidence is required to inform patients, doctors and providers in the EU when choosing between these treatments. We have therefore started an international randomised trial to compare the risks and benefits of stinting with endarterectomy. A European network of centres will harmonise stinting techniques, safeguard the safety of EU patients thus treated and ensure the trial results are general sable throughout the EU.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Combustion diagnostics' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

PROJECT OBJECTIVES The project involves the development and demonstration of a new instrument suitable for combined measurement of furnace gas conditions in the high temperature zones during biomass combustion. An new improved High Temperature Anemometer (HTA) suitable for accurate measurement of gas velocity and direction will be developed and calibrated against known measuring techniques in a pulverized coal fired test facility and then combined with an oxygen probe and thermocouple to provide accurate simultaneous measurements during operation in a 5 MW grate fired biomass furnace. TECHNICAL APPROACH The project consists of three phases, Phase 1 will be to investigate the gas flow and particle tracking across the instrument using computational fluid dynamics (CFD). This will assist in determining the requirements for the instrument head profile and vane wheel angle to provide maximum cooling for higher temperature operation in the harsh environment. Phase 2 will be the manufacture, evaluation and calibration testing of the components which form the fundamental part of the instrument. Based on the CFD analysis several instrument heads and vane wheel geometry's will be manufactured and tested in a 88MW thermally rated test facility in the UK firing pulverized coal. The final arrangement will be selected and calibrated under controlled firing conditions against measurements taken using a Laser Doppler Anemometer (LDA). During this phase consideration will be given to combining the HTA with the oxygen and temperature probes which will be employed during the testing. The final phase of the project is to apply the new instrument in a biomass fired boiler and demonstrate its capability to withstand the harsh operating environment and evaluate its capability and effectivenes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Pushing a last cost integration of green electricity into the European grid' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

The core objective of this proposal is to enhance the proportion of electricity from renewable energy sources (RES-E) in the EU by applying a least-cost approach. A derived objective is to consider the costs of and the interactions between all important supply-side and demand-side options.These options are:(i) the technical constraints of the grid for access, transmission, and storage for RES-E;(ii) the cost of an upgrade and/or extension of the grid to integrate an increased amount of new RES-E;(iii) the costs and technical opportunities of advanced storage technologies;(iv) the cost of reducing electricity consumption or load by means of DSM.Another objective is to consider various scenarios of electricity supply and demand as well electricity prices in liberalised markets. This analysis will be conducted in a dynamic framework. Considering all these options it will be ensured that a certain quota of RES-E will be met with lowest costs for society.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Fronts and Atlantic Storm Track Experiment' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

FASTEX is a field experiment designed for providing understanding of the structure, dynamics, formation and decay of the cloud systems constituent of the North-Atlantic storm track. The unique feature of FASTEX is the desire to provide a bridge, for the first time, between the large-scale dynamics of cyclogenesis and the consequent mesoscale and cloud-scale processes within the storms. This holistic approach is very demanding in requiring a description of features such as the upper jet stream on synoptic scales at the same time as detailed radiative, dynamical and cloud structures. This has not been attempted before but it is crucial if the phenomenon is to be described in a complete enough way for inclusion in, and verification of predictions from, large-scale climate models. This goal will be achieved by means of a two-months field experiment. The observing system is multilocated and mobile. Among other things, it has an Upstream Component based on ships and aircraft in mid-Atlantic and a Multiscale Sampling Area of Ireland and based on instrumented aircraft flying in a coordinated way. The present proposal is concerned with the field experiment itself, the delivery of the FASTEX data base and the first steps towards derivation of scientific understanding. The objectives of this proposal are:  to conduct a field experiment, FASTEX, concerning cloud systems within extra-tropical cyclones. The observing system is such that it will provide a unique data set: (i) relating to the initiation of storms in the mid-Atlantic storm-track, (ii) relating to the structure of the developing cloud-cyclone system near western Europe.  to exploit and analyse the data emphasizing two areas:  - the development and validation of a set of parameterizations of cloud-related processes within
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Enhancement of Customer-Supplier Relationship' (ECSR), addressing dissemination and exploitation.

assistant: **Impact**

The goal of this Best Practice Take-Up Action Project is enhancement of CAD-UL's (CAD-UL AG, CAD-UL Ltd., CAD-UL AB. and CAD-UL Inc. as associated partner) customer-supplier relationship by considerable improvement of our Customer-Supplier-System (CSS). The main service goals for this are:- Improvement/Extending of customer and partner integration in the life-cycle management of projects and services- Providing news, changes and additional information about our products- Enhancement of maintenance service- Simplifying the upgrade and update process and service- Simplification of trading- Integration of an embedded project management for partners in hard- and software- Integration of a customer feedback by continual customer surveys
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Protective Composite Gloves for Health Care'.

assistant: **Objectives**

Accidently, needlesticks and syringes puncture gloves and injure the skin. Millions of cases are counted in European health care and worldwide, each year. When perforated, medical gloves loose it's barrier function. Health care professionals are no longer protected from body fluids, potentially carrying blood-borne diseases including hepatitis B/C and HIV. Studies estimate the economic costs due to needlestick injuries to amount to more than 1 bn. € per year. Polymer-ceramic composites can reinforce polymers. Similar to bullet-proof vests, the materials provide protection against mechanical impact. Accordingly, thin gloves from polymer-ceramic composites maintain the users tactile sense. Gloves from these new materials provide unrivaled donning and wearing comfort. The patent-pending invention builds on large-scale available substances for tailor-made material components. Protective composite gloves undercut competition in price and surpass in function.The predicted world market volume for disposable gloves is 10 bn. $ in 2023; the segment of surgical gloves is 2 bn. $, the servicable market about 1 bn. €. Considering the immense potential of our solution, the application creates in an innovative and productive manner a business opportunity to introduce puncture-resistant gloves to a broad market.By pursuing the present feasibility study, the management team aims to improve its understanding of the global market conditions. The associated risks and a more detailed business plan are scheduled for rolling out and scaling up a first product as a marketable innovative solution. SME Instrument Phase-1 and Phase-2 would be extremely beneficial in helping the company accelerate the development and market penetration in the target segment, boosting the company’s growth to over
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Deciphering host-gut microbiota spatio-functional plasticity in inflammation', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Over the past two decades, gut bacteria have emerged as major regulators of human health. The focus in the field thus far has been on bacterial taxonomy, with their spatial organization and functionality largely overlooked. Crohn’s disease (CD) vividly portrays this spatiofunctional dimension, as it features patches of gut inflammation (skip lesions) surrounded by uninflamed regions—in the same host—with a clear demarcation but unknown cause. Our preliminary data demonstrate host-microbe functional feedback loops in which bacterial strains can adapt and modify their immunomodulatory functions in response to the host. Moreover, we find functional alterations in gut bacteria of IBD patients. Thus, we hypothesize that bacterial spatio-functionality can be largely affected by host physiology, and, in turn, modulate the pathophysiological state, creating a functional feedback loop.We propose to study bacterial spatiofunctional plasticity and mechanisms of host-microbe interactions in CD, and their potential causal effects on inflammation, combining microbiology, immunology and systems biology approaches. We intend to focus on three independent yet complementary aims: (1) Characterize host-microbe spatio-functional alterations in skip lesions and assess their potential causal effects on inflammation; (2) Decipher the functional and molecular mechanisms of host-microbe feedback loops in healthy and inflamed intestines; and (3) Develop a toolbox for high-resolution functional analyses of gut bacteria directly in their natural environments.This study will address, for the first time, bacterial functional plasticity in response to host inflammation, unveiling the phenomena, its mechanism of action, and potential causal effects on gut inflammation. Such understanding can shift our
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Affective Vélomobilities of Care: a Gender-Sensitive Approach to Sustainable Mobility'.

assistant: **Concept**

Within Europe, women spend up to twice as much time on unpaid care work as men do and mobility related to care tasks represents a significant part of womens daily travel. Escorting children tends to be unequally distributed amongst parents and they are much more likely to travel with their mothers than with their fathers. By introducing the novel concept of affective vlomobilities of care that focuses on the use of bicycle for accompanying children to their everyday activities, VELOCARE addresses a critical research question that is often ignored in most cities: how does the urban environment either contribute to or exacerbate gender disparities by facilitating or impeding the mobility of women who escort their children? Through the implementation of a policy-oriented interdisciplinary approach and innovative methodology that builds on sensory data, the research examines the broader implications of these dynamics on the emotional bonding of the mother and child, and on womens choice to adapt cycling as an environmentally sustainable mode of transportation in Tallinn, Estonia. Putting emphasis on the soft aspects of everyday travel, the research will advance knowledge that will help put affect and care at the centre of mobilities planning and make cities more inclusive of the needs of women and children.


**Keywords:** mobility of care, affective atmospheres, gender-sensitive planning