RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Sixth european symposium on stratospheric ozone'.

assistant: **Concept**

The Sixth European Symposium on Stratospheric Ozone will take place from September 2 to 6 2002. Its aims are to promote discussion of the scientific results of groups from across Europe; to foster collaborations between research groups in Europe; to enhance integration of EC and nationally funded research; to discuss the issues of future scientific and societal concern; and to further the training of young scientists.This proposal will provide support for the efficient preparation and organisation of this Symposium to be achieved through making the local arrangements (meeting rooms, materials for the symposium, block bookings at hotels, etc.) and by assisting the symposium's organising committee (drafting of announcements, collation of submitted abstracts, etc.). A further aim will be to provide travel support for young scientists and for scientists from accession countries.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Vaccination against Shigella and ETEC: novel antigens, novel approaches' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

To contribute to the development of vaccines against Shigella and ETEC for children of the developing world, STOPENTERICS will provide novel solutions by imposing a two-fold paradigm switch: (i) to break the dogma of serotype-specificity by inducing a cross-protective immunity (ii) to improve the immunogenicity of Shigella glycoconjugates by using synthetic oligosacharides mimicking the lipopolysaccharide O-antigen. The possibilities offered by genomics/proteomics and bacterial outer membrane blebs (OMB) will be exploited to identify virulence proteins conserved throughout Shigella or ETEC isolates. For ETEC, the development of a safe, immunogenic ST (heat stable) toxoid is a priority. State-of-the-art glycochemistry and sugar-protein carrier conjugation will allow engineering optimal Shigella glycoconjugates with focus on the five most prevalent serotypes. The ultimate aim is to optimize chances for the best coverage by combining cross-protective and serotype-specific antigens, thus ensuring the development of efficient multivalent vaccines that will help reduce the burden of diarrheal diseases. At all stages of the R & D process, candidate antigens will be considered in light of immunomonitoring data obtained in naturally-infected individuals, and volunteers undergoing vaccine trials. Regarding the latter, Phase-1 clinical trials with two vaccine candidates are planned as proofs–of-concept of (i) a synthetic oligosaccharides approach mimicking Shigella O-antigens, and (ii) a Shigella OMB-based vaccines to be tested after validation of preclinical studies. STOPENTERICS is a unique combination of laboratories, platforms, vaccinology centres from academia and industry in the North and the South, integrated to successfully develop new vaccines, from R&D toward clinical tr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Non-local mesoscopic cat states and quantum information' (CATINFO).

assistant: **Innovation**

We plan to build a new cavity QED self-up for fundamental tests of quantum effects and for the demonstration of quantum information processing functions. We will use circular Ryder atoms and super conducting cavities in the millimetre-wave domain. Both the atomic levels and the cavity modes have very long lifetimes. Their coherent coupling overwhelms dissipation. This makes it possible to realize complex entanglement sequences and to manipulate macroscopic quantum superpositions. This domain has already provided interesting experimental insights into quantum information techniques. We plan to extend the realm of these experiments much farther by entangling two separate cavities with a single atomic beam. The two independent field modes will be used for new and quantitative tests of the lecherous processes. They make it possible to realize unprecedented quantum states, entangled pairs of macroscopic objects (non local Schrödinger cat states). The study of these quantum states will lead to a deeper understanding of quantum on-locality, which is at the heart of the power of quantum information transmission (particularly with continuous variable approaches). We will also study the lecherous process for these macroscopic quantum superpositions. The lecherous dynamics will be investigated, for instance, through the determination of the complete two-mode Wagner distribution. This detailed understanding of lecherous is an essential point to assess the limits set by relaxation on quantum information processing and to learn how to fight it. This cavity QED set-up will also be used for quantum information processing. The two cavities and the ability to manipulate four or five atomic samples in an experiment allow realizing rather complex sequences. We will study the teleportation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'A New Foundation for Computer Graphics with Inherent Uncertainty' (FUNGRAPH).

assistant: **Innovation**

The use of Computer Graphics (CG) is constantly expanding, e.g., in Virtual and Augmented Reality, requiring realistic interactive renderings of complex virtual environments at a much wider scale than available today. CG has many limitations we must overcome to satisfy these demands. High-quality accurate rendering needs expensive simulation, while fast approximate rendering algorithms have no guarantee on accuracy; both need manually-designed expensive-to-create content. Capture (e.g., reconstruction from photos) can provide content, but it is uncertain (i.e., inaccurate and incomplete). Image-based rendering (IBR) can display such content, but lacks flexibility to modify the scene. These different rendering algorithms have incompatible but complementary tradeoffs in quality, speed and flexibility; they cannot currently be used together, and only IBR can directly use captured content. To address these problemsFunGraph will revisit the foundations of Computer Graphics, so these disparate methods can be used together, introducing the treatment of uncertainty to achieve this goal.FunGraph introduces estimation of rendering uncertainty, quantifying the expected error of rendering components, and propagation of input uncertainty of captured content to the renderer. The ultimate goal is to define a unified renderer exploiting the advantages of each approach in a single algorithm. Our methodology builds on the use of extensive synthetic (and captured) “ground truth” data, the domain of Uncertainty Quantification adapted to our problems and recent advances in machine learning – Bayesian Deep Learning in particular.FunGraph will fundamentally transform computer graphics, and rendering in particular, by proposing a principled methodology based on uncertainty to develop a new gen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Active reduction of noise transmitted into and from enclosures through encapsulated structures' (IN-NOVA) targeting Horizon Europe.

assistant: **Abstract**

To better reduce exposure of people to noise and increase their acoustic comfort, innovative noise barriers should be developed. The overarching aim of IN-NOVA is to provide a top-level training for 10 Doctoral Candidates (DC) - MSCA Fellows plus 3 DCs funded by UK (supervised by UCL - 1 DC and UOS - 2DCs), in a wide variety of cutting-edge noise control technologies, developing a new generation of creative and entrepreneurial innovators. The DCs will benefit from a unique soft-skills training programme that will kick-start their careers as highly employable professionals. To reach these goals, IN-NOVA has pooled the interdisciplinary, complementary and multisectoral expertise of leading research universities and innovative global companies in the fields of acoustics, vibration, materials engineering, signal processing, and control sciences, represented by outstanding researchers and practitioners. All SRs will get strong intertwining academic and non-academic supervision to jointly develop novel, complete concepts for innovative barriers to reduce noise transmitted into and from enclosures through encapsulated structures (dual problems), thus creating a more pleasant and healthier local soundscape in workplaces and leisure areas as well as in car and aircraft cabins. They will use structural design, destructive interference of waves, holistic approaches to soundscape forming, metamaterials, and employ advanced combined active, novel passive and semi-active technologies. The IN-NOVA research, training and outreach activities will have an important and lasting impact on the DCs, members of the consortium, individual people, society, environment, international scientific community, industry, policy makers, and on the EU as a whole. It will propose first standards and labe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'From the earliest modern humans to the onset of farming (45,000-4,500 BP): the role of climate, life-style, health, migration and selection in shaping European population history' to be submitted under Seventh Framework.

assistant: **Abstract**

The colonisation of Europe by anatomically modern humans (AMHs) ca. 45,000 years before present (BP) and the transition to farming ca. 8,000 BP are two major events in human prehistory. Both events involved certain cultural and biological adaptations, technological innovations, and behavioural plasticity which are unique to our species. The reconstruction of these processes and the causality between them has so far remained elusive due to technological, methodological and logistical complexities. Major developments in our understanding of the anthropology of the Upper Palaeolithic, Mesolithic and Neolithic, and advances in ancient DNA (aDNA) technology and chronometric methods now allow us to assess in sufficient resolution the interface between these evolutionary processes, and changes in human culture and behaviour.The proposed research will investigate the complex interface between the morphological, genetic, behavioural, and cultural factors that shaped the population history of European AMHs. The PI s interdisciplinary expertise in these areas, his access to and experience of relevant skeletal collections, and his ongoing European collaborations will allow significant progress in addressing these fundamental questions. The approach taken will include (a) the collection of bioarchaeological, aDNA, stable isotope (for the analysis of ancient diet) and radiometric data on 500 skeletons from key sites/phases in Europe and western Anatolia, and (b) the application of existing and novel aDNA, bioarchaeological and simulation methodologies. This research will yield results that transform our current understanding of major demographic and evolutionary processes and will place Europe at the forefront of anthropological   biological and genetic   research.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Inossia Cement Softener - a new and unique additive to bone cements to revolutionise the treatment of vertebral fractures in osteoporotic patients' (SMART-SOFT).

assistant: **Concept**

The Inossia Cement Softener is an additive (a softener) for bone cements that lowers their stiffness by 50-75% and adjusts it to that of the bone it is injected into. This does not alter the spinal biomechanics to the extent that the currently used cements do which in turn  reduces the risk of new unnecessary vertebral fractures by 75%.The Inossia Cement Softener has the potential to become a true game-changer and revolutionise the outcome of vertebral augmentation treatments in osteoporotic patients:the patients will experience immediate pain relief, allowing them to go back to everyday life without the risk of rehospitalization, the clinicians will be able to offer an efficient treatmentthe healthcare payers will save money previously unnecessary spent on the retreatment of already treated patients  Our innovation is designed to revolutionise the treatment of osteoporosis, ensuring a healthy and active ageing.


**Keywords:** vertebral augmentation,osteoporosis,vertebral fractures,bone cement softener
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Medical Complicity: A New Normative Account and Its Implications for Three Study Cases' (MedCom).

assistant: **Innovation**

Traditionally, discussions in medical ethics have focused on ways in which medical professionals may do wrong by directly  harming or wronging patients or research subjects. However, medical professionals may also act wrongly in indirect ways, by being accomplices to others' wrongdoing (e.g. by taking part in torture, a doctor may become complicit in torture). Moreover, the effects of medical complicity can aggregate to produce substantial wrongs, such as gross human right violations (e.g. the complicity of doctors in Nazi eugenics facilitated genocide). But medical complicity is also ubiquitous in everyday medicine (e.g. nurses assisting in wrongful end-of-life practices may become complicit in these practices). Professional guidelines frequently give no clear guidance on how to deal with medical complicity. They either do not address the issue, or give conflicting advice (e.g. the same codes that condemn complicity in torture also state that the physician should act in the best interest of the patient, but these professional obligations could conflict when the patient is a torture victim).Though medical complicity can have significant effects and is presenting medical professionals with unresolved ethical dilemmas, problems of medical complicity have received little sustained theoretical treatment in medical ethics. Most existing discussions either remain at the level of complex philosophical theory, or at the level of practical decision-making with little philosophical basis. This project aims to bridge this gap. It will do so by developing a clear account of medical complicity, and by deploying this account to yield concrete guidance for medical professionals and policymakers confronted with dilemmas of medical complicity. To achieve these aims, I will draw on novel
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'An integrated experimental and mathematical approach to investigating endothelial barrier integrity in health and cerebral malaria' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The integrity of the endothelial barrier is vital for maintaining healthy brain function and is especially compromised in pathological conditions such as cerebral malaria. Despite its significance, the current understanding of the mechano-chemical mechanisms operating at sub-cellular, inter-cellular, and tissue scales within endothelial barriers during cerebral malaria remains limited. This project aims to close this knowledge gap by integrating advanced in vitro experimental methods with multi-scale mathematical models. Through a multi-tiered methodologyincluding single-cell assays, 2D endothelial monolayer cultures, and 3D brain microfluidic deviceswe plan to assemble a comprehensive dataset that captures the complex mechano-chemical processes underlying endothelial function and dysfunction. This rich dataset will facilitate the data-driven development, calibration, and validation of a new multi-scale mathematical model, along with a high-performance computational framework for its solution. The validated models will subsequently be used to design targeted experiments aimed at dissecting the molecular mechanisms regulating endothelial integrity. Our interdisciplinary approach is uniquely poised to cultivate a dynamic interplay between experimental data and mathematical modelling, leading to a more holistic understanding of the mechanisms responsible for endothelial integrity in healthy states and how they are compromised in the cerebral malaria condition. Ultimately, this strategy aims to provide an in-depth understanding of the endothelium, which could, in the long term, aid in the development of therapeutic interventions for cerebral malaria.


**Keywords:** Endothelial Cell, Parasite, Cerebral Malaria, Microfluids, Mathematical modelling, Finite element
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'EIT Cross-KIC Shared Services' (2021-2027), addressing dissemination and exploitation.

assistant: **Impact**

The Shared Services Cross-KIC’s objective is to identify and create opportunities for KICs to achieve synergies across different common area of concern. EIT KICs by design have a specific status that requires them to adhere to requirements set by EIT and the EC in order to be eligible to receive funding. The Shared Services Cross-KIC tackles these requirements (largely specified in the Call document) through different activities: (1) CLC Consolidation to achieve efficiency and impact in building the required KICs’s presence in Europe while enabling facilitate collaborations; (2) Communicate and Disseminate the results of KICs activities and engage with the EU policy debate through EIT Community common events (InnovEIT, CLC Open days) as well as flagship premises to engage with specific ecosystems (EIT House Brussels, EIT Hub Budapest), and (3) comply to operational requirements with an efficient and common approach, such as joint procurement of Audits for CFS, verification on New Partners, and a common IT tooling to manage the EIT Grant and related reporting.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Probabilistic modelling of electronic health records' to be submitted under Horizon 2020.

assistant: **Abstract**

The growing worldwide adoption of Electronic Health Records (EHR) enables new research opportunities to analyse massive amounts of medical information, motivated by the promise of improving health systems while providing significant budget savings. Biomedical research increasingly uses machine learning methods as a data-driven approach to learn complex comorbidity patterns of diseases, study drug interactions, and form predictions. The analysis of EHRs may not only lead to knowledge discovery, but it also facilitates personalised medical treatment and early diagnosis of the diseases through the design of clinical support systems.However, current approaches for the analysis of EHRs are still in their early stages. The two main technical challenges that need to be addressed are integration of heterogeneous data and scalability to massive datasets. Most of the existing methods are tailored to homogeneous data and, therefore, to a single source of information, and hence they cannot handle EHR datasets. Scalability also represents a difficulty for most of the current machine learning techniques, which are limited to the analysis to moderate-sized datasets.In this project, we will develop novel tools for the analysis of heterogeneous EHR data. Our approach will be based on probabilistic modelling techniques, since they are an effective approach for understanding real-world data in many areas of science. We will make use of Bayesian nonparametric modelling techniques, coupled with stochastic variational inference to allow for scalable inference. Probabilistic models, including BNPs, are amenable to both descriptive and predictive analysis at the same time. We will collaborate with the Department of Biomedical Informatics, who will provide their knowledge about the problem, all