RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Co-existence between auction markets and dealership markets' (1994-1998).

assistant: **Concept**

Research objectives and content The project will investigate the co-existence between auction- and dealershipmarkets. The driving force to offer both trading systems at one exchange is to regain the market share lost to London. The question whether exchanges should organize both trading systems is important from a policy viewpoint. In particular, is it optimal for traders to have one big financial dealershipmarket (e.g. in London) or should different financial markets co-exist. We expect two forces to determine the outcome. The first is fragmentation. The more markets co-exist, the more trade becomes fragmented, lowering liquidity. The second force is competition. Co-existence of financial markets generates competitive forces enhancing liquidity and reducing the cost of capital. We will discuss the effects of co-existence on transparency, liquidity, cost of capital and trading volume. Training content (objective, benefit and expected impact) CentER at Tilburg University has a tradition in game theory and econometrics. In addition, it is well known for its expertise on the organization of financial markets. Professrs de Jong, Nijman and Roell affiliated at Tilburg University are experts in the analysis of competition between financial markets. Their expertise concerns theoretical as well as empirical work. Interaction with them is a guarantee for a successful project. The data for the empirical analysis are available at CentER. Links with industry / industrial relevance (22) The project has links with financial markets. In particular, it is relevant for the continental exchanges as well as the London stock exchange.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'HYDROPOWER-EUROPE' (HYDROPOWER-EUROPE).

assistant: **Concept**

The transformation of Europe’s energy system creates both challenges and opportunities for the hydropower sector. Hydropower needs to seek out value within the electricity market aligned with other sources of renewable and sustainable energy, whilst operating and building plants in environmentally sensitive and acceptable ways. The call H2020 LC-SC3-CC-4-2018: “Support to sectorial fora”, item 2: “bringing together stakeholders of the hydropower sector in a forum” provides a unique opportunity to bring together the hydropower community and to develop a Research and Innovation Agenda, and a Technology Roadmap mapping implementation of that agenda. These will support implementation of research and innovation for new hydropower technologies and innovative mitigation measures.The HYDROPOWER-EUROPE project delivers these objectives through an extensive programme of stakeholder consultation.  The consortium brings together six different associations and networks spanning the whole research and industry value chain.  These networks, along with representatives of civil society and European and national authorities, will form the initial stakeholder consultation base.  Through an extensive, cyclic programme of consultation – both online and through various regional, European and International workshops – research needs and priorities will be established supporting development of the Hydropower Research and Innovation Agenda.  The consultation process also facilitates discussion around issues and perceptions affecting the implementation of hydropower in Europe.  Conclusions from this will underpin development of the Technology Roadmap, addressing any issues affecting uptake of the research and innovation agenda.Finally, the HYDROPOWER-EUROPE project will also consider ways in whi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The development of an automated system for the cutting and planting of rose cuttings' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

The propagation of roses by cuttings is one of the most applied (propagation) methods. At present the cutting and planting of pot roses is a manual process/procedures. The rnajor (technical) limitations are the low productivity and the variations in quality. Moreover, it is a boring job. Therfore, the objective ofthe intended R&D-project is to develop an automated system for the cutting and planting of rose cuttings which has the following specifications: 1) a high productivity (2 7200 cuttings/h), 2) a high and uniform quality, and 3) a short through-put time (reduction of the chance of infection). The proposed system will be composed of a number of innovative techniques, such as a recognition (vision) system, a robotic system and a handling clip system. Preliminary estimates show that the potential benefits (industrial impact) of such a system are favourable compared to the (development) costs. A prototype will be built whicch will provides the data for the design of a commercial automated system for the cutting and planting of rose cuttings. The consortium consists of developers and endusers ofthe proposed system. The propagation of roses by cuttings is one of the most applied (propagation) methods. At present the cutting and planting of pot roses is a manual process/procedures. The major (technical) limitations are the low productivity and the variations in quality. Moreover, it is a boring job. Therefore, the objective of the intended R&D-project is to develop an automated system for the cutting and planting of rose cuttings which has the following specifications: 1) a high productivity (2 7200 cuttings/h), 2) a high and uniform quality, and 3) a short through-put time (reduction of the chance of infection). The proposed system will be composed of a number of innov
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Unravelling the eukaryotic post-transcriptional regulatory code' to be submitted under Horizon Europe.

assistant: **Abstract**

Genomes encode instructions for cells to regulate gene activity in response to their environment. However, and despite its importance for biology, medicine and biotechnology, the underpinning regulatory code remains undeciphered. Gene regulation consists of two major steps. First, genes are transcribed into mRNA. Second, post-transcriptional mechanisms regulate mRNA stability and the rate at which it is translated into proteins. This second step of gene regulation is still poorly understood because relevant parameters such as mRNA half-life, mRNA protein binding and subcellular localization are difficult to assay. The lack of understanding of post-transcriptional regulation implies that we still do not have a complete picture of the regulatory code. In EPIC, we exploit the advantages of the model eukaryote Saccharomyces cerevisiae and other species covering a broad evolutionary range to derive the first comprehensive sequence-based model of eukaryotic gene regulation. EPIC integrates the complementary expertise of 3 teams. It combines innovative high-throughput technologies (Pelechano) to probe post-transcriptional regulation at an unprecedented scale across a broad range of species and conditions with synthetic biology to massively test regulatory sequences (Verstrepen). Deep learning on these data allows us to build predictive models and unravel complex regulatory instructions (Gagneur). Ultimately, EPIC will enable us to decipher the actual language of gene regulation and facilitate (re)writing genomes. EPIC will enable understanding and predicting regulation, and ultimately phenotype, from DNA, closing a major gap in basic biology, while also opening exciting avenues for applications in biotechnology and medicine, from pinpointing disease-causing mutations to ration
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The value of mothers to society: responses to motherhood and child rearing practices in prehistoric Europe' under Horizon 2020.

assistant: **Concept**

Analysing the link between reproduction and women’s social status, this project explores social responses to pregnancy, birth and childrearing from the late Neolithic to the late Iron Age (c.3000-15 BC) through case studies in central Europe. Motherhood and childrearing, often seen as natural, mundane and inevitable parts of women’s lives, are also cultural and historically contingent practices that build the foundations of societies. Exploring the value of mothers to society will aid in understanding important long-term developments such as social stratification, increasing population density and the entrenching of gender roles during the three millennia under investigation. Bringing together the latest developments in archaeological science, including palaeo-pathology, ancient DNA and isotope analyses, with innovative interpretative approaches, this project will explore if all women were expected to become mothers, highlight alternative lifeways, evaluate risks and consequences of becoming a mother and analyse the social value of reproductive success.It is the first study that aims to systematically predict the probability of whether or not a woman has given birth using palaeo-pathological markers combined with individual age information and population-specific demographic data. It will contextualize the findings with an in-depth status analysis of women’s graves. Graves of pregnant women, double burials of women and children as well as infant burials will provide further data. The study extends to childrearing (care, feeding, but also abuse, neglect and infanticide) and explores how children were treated after death for insights into their significance. Current political discourses about mothers in society and workforce frequently refer to ‘natural’ and ‘ancient’ chi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Viable Wagonload production Schemes'.

assistant: **Concept**

Single wagonload (SWL) transport is still a major component in numerous European states transport systems and in the logistics of different economic sectors such as steel, chemical industry and automotive. However changing framework conditions and increasingly demanding market requirements have led to dramatic market losses and even to complete shutdown of SWL business in some countries. As this business segment has been evaluated as important for specific transports in a European co-modal transport system also in the future, significant improvements are needed. The ViWaS partners believe that for the success of SWL the following two issues might be crucial: (1) A viable SWL system is highly dependent on the critical mass. Thereby all options have to be considered to secure a high utilisation of the trains operated on the trunk lines, including a combined production with intermodal loads. (2) Only comprehensive and complementary measures are able to sustainably improve and preserve the European SWL systems in accordance with increasingly demanding market requirements. The ViWaS project will follow such a comprehensive approach; therefore aiming at the development ofMarket driven business models and production systems to secure the critical mass needed for SWL operations,New ways for “Last mile” infrastructure design and organisation to raise cost efficiency,Adapted SWL technologies to improve flexibility and equipment utilisation,Advanced SWL management procedures & ICT to raise quality, reliability and cost efficiencyThe applicability of these solutions and their effects will be proved on the basis of pilot business cases (by demonstrations).Thereby important findings will be gained for a European wide implementation of developed solutions.The ViWaS consortium includes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Spin and Orbital Physics : Research of Advanced New Oxides' under Seventh Framework.

assistant: **Concept**

The remarkable physical properties of transition metal oxides result from the strong interactions between orbitals, charges, spins and lattice. The discovery and the understanding of these properties – superconductivity, thermoelectricity, magnetoresistance – is based on a close relationship between solid-state chemists, able to design new crystallographic structures in which the ligand field stabilizes different types of cations, and solid-state physicists and specialists of spectroscopic techniques, such as absorption at the transition-metals and oxygen edges or local probes, who are able to extract the characteristic electronic and magnetic features of these cations. In the scope of this network, the search for new compounds will be made by standard solid state chemistry in Caen (CRISMAT) and Bordeaux (ICMB) laboratories, also in charge of the structural and physical property characterizations, by high pressure techniques in Liverpool and Madrid, and by hydrothermal synthesis in Timisoara. The origin of physical properties will be studied in close relationship by different spectroscopy techniques (XANES, dichroïsm: Köln University; Raman, IR conductivity, inelastic neutron scattering: MPI Stuttgart). The collaboration between new oxides discoverers and specialists of the orbital/spin physics will allow the creation of a unique training and research potential on metal-transition oxides. Furthermore, the involvement of the industrial partner (NXP) will provide strong benefit to all members of the network by demonstrating how to iterate fundamental science advances into technology and process development. The proposed investigation, being at the spearhead of the modern condensed matter physics and solid state chemistry, will give an excellent opportunity to teach and tr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Hydrogen Industrial Inland Valley' under Horizon Europe.

assistant: **Concept**

The HI2 Valley project will establish a large-scale renewable hydrogen (H2) economy in the Austrian industrial regions of Upper Austria, Styria and Carinthia, directly contributing to the goals outlined in the European Green Deal, REPower EU and Hydrogen Strategy. The project will achieve this by decarbonising key sectors through H2, drastically reducing emissions in the steel, chemical, and cement industries as well as in energy and mobility via displacement of fossil fuels – including reducing the reliance on natural gas which Austria overwhelmingly imports from Russia. With 13,000 tons of green hydrogen being needed in the regions by 2028, over 10,000 tpy of green hydrogen will be produced within this HI2 Valley.   By introducing strategically placed, decentralised H2 production facilities, the project will strengthen the country's energy resilience and flexibility and create a robust domestic market for green H2. The HI2 Valley will play a crucial role in bridging the gap between Southern and Eastern European hydrogen supply corridors. Being embedded on the European Hydrogen Backbone and TEN-T network and future pipeline connections (PCIs) with Southern Europe and North Africa, the HI2 Valley will seamlessly connect Austria's multi-user H2 ecosystem with neighbouring countries like Germany, Italy and Slovakia, fostering a truly interconnected Central European hydrogen network. This role model helps to secure industrial jobs, and through standardisation and integration brings costs of hydrogen down, creating a green industrial future for Europe. Going beyond its immediate neighbours, the HI2 Valley will also foster knowledge sharing and wider adoption of green hydrogen through the active collaboration with five other emerging Hydrogen Valleys in Eastern Europe in Pol
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Strengthening the European Chain of sUpply for next generation medical RadionuclidEs' (SECURE).

assistant: **Innovation**

SECURE project aims to make a major contribution to the sustainability of medical isotope production and its safe application in Europe. It is focusing on promising developments in the design of irradiation targets, production routes for existing and new isotopes in nuclear therapy and diagnostics. Isotopes critical in the success of nuclear medicine are selected and research activities are identified to address some of the major challenges in securing its future availability, with the objectives:1.to remove critical barriers along the production of its selected alpha and beta emitting isotopes that restrict a sustainable production, 2.to develop a framework of guidance and recommendations that enables exploring the full clinical potential of alpha and beta particle therapy and its safe application 3.to provide important lessons learned that act as a demonstration case for addressing issues in upscaling and sustained isotope production.At present, Ra-223 is the only radiopharmaceutical which has been granted marketing authorization to treat adults with prostate cancer. This has paved the way for a wider use of other alpha emitters such as Ac-225 or Bi-213. The expected demand of nuclear medicine for novel alpha emitters and beta- emitters requires re-evaluation of their production methods and inventories of target materials and parent radionuclides.  The ambition of SECURE consortium is to identify and efficiently use the current resources for new radionuclides, in particular for alpha emitters and the relevant beta emitting theranostic radionuclides.  The development of alternative technologies for production of such therapeutic radionuclides for improved patient treatment requires multidisciplinary scientific and technological knowledge including physics, chemistry, m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Clinical development of Rift Valley fever vaccines in endemic regions' (RIFTVAX), addressing dissemination and exploitation.

assistant: **Impact**

Initial funding was provided to the Coalition for Epidemic Preparedness Innovations (CEPI) in 2019 which was used to support preclinical and clinical development of Rift Valley fever (RVF) and Chikungunya (Chik) vaccines respectively. This funding was provided to applicants as a joint effort between CEPI and the Horizon 2020 programme, under the CEPI Call for Proposals CfP3i. Whilst previous funding has led to the development of pre-licensure Chik vaccines, development of RVF vaccines is at a much earlier stage. Hence, this current application seeks to leverage a further 35M from Horizon Europe, which will be supplemented with 15M from CEPI, making a pool of 50M, which will be used to fund clinical development of RVF vaccine projects under the CEPI follow-up Call for Proposals CfP3ii.It is envisaged that applicants for the CfP3ii funding will have already developed a manufacturing plan and that all preclinical studies have been completed (with the possible exception of Development and Reproductive Toxicology (DART) studies). Applicants will propose Phase I/II trials in endemic regions for vaccines which are in accordance with the WHO Target Product Profile (https://www.who.int/docs/default-source/blue-print/call-for-comments/tpp-rift-valley-fever-vaccines-draft3-0pc.pdf?sfvrsn=f2f3b314_2) for RVF vaccines.Awards will usually have a 36-month duration and will be administered by the CEPI secretariat.


**Keywords:** Vaccine, Rift, Clinical