RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'WIRE - Widening Innovation+Research Excellence in FilmEU)' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

WIRE  is promoted by all eight HEIs currently members or soon to be members in the FilmEU Alliance. FilmEU fully represents Europe’s geographical, cultural, and linguistic differences, combined with the diversity and richness of its European Higher Education Area (EHEA) and its Research Area (ERA). WIRE integrates five out of eight academic partners each coming from widening countries, a majority of less research-intensive institutions and is led by an institution from a widening country. All WIRE activities are centered in widening countries, and it is these countries and less research-intensive HEIs that are beneficiaries of the of the project. WIRE’s main objective is to catalyse a step change in the excellence and innovation of the science and value creation activities carried out by and across the FilmEU Alliance via its capacity building and the promotion of several reforms across the HEIs in widening countries participating in the Alliance. WIRE will capacitate the FilmEU Alliance Research and Innovation R&I dimensions, notably by focusing on management and administrative competencies, for the benefit of its members in widening countries, and through that increase the overall competitiveness of the Alliance. WIRE will achieve this through deeper and more geographically inclusive cooperation between all members of the Alliance. WIRE will contribute significantly to the expected outcomes of the call via the consolidation of an inclusive Alliance of HEIs which mostly (5 of 8) come from widening countries. Through collaboration between themselves and with other actors in local ecosystems, they will promote institutional and country-level reforms and upgrades, facilitate an embedded culture of excellence and value creation driven by artistic research, and focus on the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Hierarchical classification, mining and semantic retrieval in remote sensing image archives'.

assistant: **Innovation**

Remotely sensed imagery has become an invaluable tool for scientists, governments and the general public to understand the world and its surrounding environment. Automatic content extraction and efficient access to this content have become highly desired goals for developing intelligent systems for effective processing of these images. This project aims to research automatic techniques for semantic processing of remotely sensed images, extraction of the relationships between them, efficient storage of these relationships in databases, improved access to the stored information, and comparisons between new information and past cases. The proposed work includes methods from computer vision, pattern recognition, machine learning, database systems and data mining areas.Semantic processing of images will be done using a hierarchical decomposition. First, clustering and density estimation will be performed on pixel data and these pixels will be classified using a fusion of the estimated densities for different features. Next, segmentation techniques will be used to group the pixels and divide images into spatially contiguous and meaningful regions. Then, relative arrangements of these regions will be modeled using attributed relational graph structures that encode perimeter-based, distance-based and orientation-based spatial relationships between regions. Data mining methods will be developed to find interesting patterns in image databases and track their evolution in time. Content-based retrieval techniques will be developed to enable semantic searches by finding matches between conceptually similar scenes. This work will enable us to analyze large image databases by their high-level semantic content instead of the limited representation supported by low-level feature vectors
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Wireless Stent-like Soft Millirobots (STENTBOT) for  Minimally Invasive Brain Vasculature Disease Treatments'.

assistant: **Concept**

Diseases in the brain vasculature, such as acute ischemic stroke, aneurysm and brain tumors, are fatal and require medical devices to treat them with minimal invasion. However, current tethered devices have limited safe access into the distal or tortuous vascular routes, which prevent saving lives of some patients. Therefore, we propose a wireless stent-shaped magnetic soft millirobot, stentbot, which would have the capability of safe access to such routes. Also, the stentbot will be able to be repositioned afterwards without repeating the same procedure fully again if the disease location changes or if the initial position of the device is observed to be not optimal. Such robot concept was originated in the ERC-AdG project of the PI. After reaching its target location safely and precisely under medical imaging and external magnetic actuation guidance, the robot will deliver the tissue plasminogen activator drugs on-demand locally to treat the acute ischemic stroke. Moreover, the robot will be used to treat aneurysms minimally invasively by becoming a flow diverter to regulate flow into the aneurysm sites.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'PReterm Enteroids to determine the Mechanism of Necrotising EnteroColitis', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Necrotising enterocolitis (NEC) is an inflammatory mediated bowel disease that causes more deaths after the first week of life in extremely preterm infants than any other single pathology, with prematurity and abnormal bacterial colonisation regarded as the most significant risk factors. However, 40 years of research have yielded few advances in treatment and the mechanisms of disease remain poorly understood. A major reason for this lack of progress relates to challenges in translating findings from non-invasive samples (e.g., stool) and the inability to robustly model bacterial-host crosstalk. To overcome this longstanding hurdle, the proposed PREMNEC (PReterm Enteroids to determine the Mechanisms of Necrotising EnteroColitis) fellowship will utilise a novel ex vivo preterm human intestinal enteroid (PHIE) co-culture model to systematically explore the gut microbiome and host functioning in preterm infants. The fellowship is divided in three distinct work packages (WPs). In WP1, surgically resected intestinal tissue (otherwise discarded) from NEC and non-NEC infants will undergo characterisation utilising metagenomics, transcriptomics, proteomics, and cellular imaging directly on the fresh tissue. Concurrently, WP 2 will isolate crypt cells from the tissue to establish PHIEs that permit accurate and reproducible ex vixo co-culture of bacterial-host interaction. In WP 3, bacterial species isolated from preterm infants will be systematically added to the ex vixo co-culture model and comparable technologies utilised in WP 1 will be applied to determine the pathobiology of disease. Newcastle University will provide expertise in state-of-the-art transcriptomics and cellular imaging technologies.Upon completion of this 24-month fellowship, I will have pioneered significant
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Development of Biocatalytic Strategies for the Synthesis of Chiral Thiols and Thioethers' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Active pharmaceutical ingredients (APIs) are crucial for public health. However, their synthesis is often challenging due to the high complexity of modern drug molecules. In particular, APIs need to have well-defined chirality as opposite enantiomers can have dramatically different biological effects. Yet, the synthesis of chiral centres is often challenging and toxic metals as well as harsh reaction conditions are often required. Enzymes on the other hand can often achieve unmatched enantioselectivities while also avoiding such environmentally unfavourable conditions. While several biocatalytic strategies for the synthesis of chiral alcohols and amines, have been developed few such strategies exist for the synthesis of chiral thiols and thioethers, despite 20% of all APIs containing sulfur. In the project described herein, I will be developing biocatalytic approaches for the synthesis of thiols and thioethers by exploring promiscuous activities of classes of enzymes widely used in industry. This will expand the tools available for their synthesis and open up new routes and new chemical space for the synthesis of APIs, and improve the sustainability. While working with Dr Caroline Paul in the Biocatalysis group at TU Delft, I will receive training in handling nicotinamide- and flavin-dependent oxidoreductase enzymes as well as specialist computational tools for enzyme engineering, while providing my experience in high-throughput screening and chemical synthesis. I will have the opportunity to co-supervise Bachelor, Master, and PhD students, and attend several key conferences. This will allow me to further develop the necessary scientific and teaching skills that are required for leading my own research group.


**Keywords:** Biocatalysis, asymmetric synthesis, chiral th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'SIADE SaaS: Spatial Decision Support System for Transportation Planning'.

assistant: **Objectives**

The demand for passenger transport will grow 51% by 2050, triggering a market growth to €100.6 billion by 2019. Smart Mobility enabled by Smart Public transport is key for cities’ economy and development. Worldwide transport operators are implementing AFCs (Automated Fare Collection) for a better urban transportation experience, generating Big Data, but lacking passenger destination information. However, turning these data into knowledge is challenged by the difficulty to accurately describe transport network states and computational burden coming from processing Big Spatial Data to derive metrics of capacity utilization, punctuality, passenger volumes at stops, or travel patterns of different user groups. SIADE SaaS is a spatial decision support system for bus transportation planning and other transportation systems where user destination is unknown. It delivers the most complete and accurate OD matrix in the transport industry using GIS and AFCs data. Our current SW has already attracted the attention of several Transport Operators in 7 countries. We are making a strategic transition from offering consultancy services to software product commercialization on global scale, using a user driven improvement of SIADE based on an incremental methodology. The evaluation of the transportation network and the potential information provided by SIADE SaaS is multidimensional: social equity, service quality, network structure and environmental impact. It helps transit agencies plan per the actual demand, enabling economic and sustainable operations, while providing the population a service more adapted to its needs. For Terrain Technologies, innovation is a key point for growth. The company devotes an average of at least 50% of its resources to RD activities in an annual basis Ou
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Unobtrusive Health Monitoring System for the Early Detection of Heart- and Micturition-Related Diseases' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

EarlyCare project aims at developing and implementing cutting-edge sensing technologies and advanced Artificial Intelligence (AI) techniques to create a Health Monitoring System enabling early prediction of Diabetes Mellitus (DM) and Congestive Heart Failure (CHF), through the continuous monitoring of vital signs of older adults’ living alone related to micturition and cardiac activities as well as their warning signs. The innovative aspect of EarlyCare solution is the efficient deployment of completely nonwearable, unobtrusive, and privacy-friendly devices such as gas sensors and wireless physiological sensors which are coupled with explainable AI to detect and analyse the underestimated warning signs (i.e., nocturia and pollakiuria as abnormal micturition activity, arrhythmia and breathlessness). The AI-powered systems will be trained using publicly accessible sets and refined during the first phase of piloting. EarlyCare will be integrated into an interoperable IoT platform (enSenior) and validated on voluntary patients. The successful conclusion of this project will contribute to promote healthy ageing and reduce burden of formal and informal caregivers of older adults by advancing in development of eHealth tools and smart devices. The proposed multidisciplinary research activities, training, transferable skills and secondments will grant the improvement and acquisition of the most appropriate skills for his future career development.


**Keywords:** Health Monitoring System, Gas sensors, Physiological data analysis, Machine Learning, Explainable Artificial Intelligence
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'An international network of 50 CubeSats for multi-point, in-situ measurements in the lower thermosphere and re-entry research'.

assistant: **Innovation**

The QB50 Project will demonstrate the possibility of launching a network of 50 CubeSats built by CubeSat teams from all over the world to perform first-class science and in-orbit demonstration in the largely unexplored middle and lower thermosphere. Space agencies are currently not pursuing a multi-spacecraft network for in-situ measurements in the middle and lower thermosphere because the cost of a network of 50 satellites built to industrial standards would be very high and not justifiable in view of the limited orbital lifetime. No atmospheric network mission for in-situ measurements has been carried out in the past or is planned for the future. A network of satellites for in-situ measurements in the middle and lower thermosphere can only be realised by using very low-cost satellites, and CubeSats are the only realistic option. The Project will demonstrate the sustained availability of low-cost launch opportunities, for launching small payloads into low-Earth orbit; these could be microsatellites or networks of CubeSats or nanosats or many individual small satellites for scientific or technological research. The Project will include the development of a deployment system for the deployment into orbit of a large number of single, double or triple CubeSats. Once, the system is developed for QB50 it can be easily adapted to other missions. QB50 will also provide a launch opportunity for key technology demonstration on IOD CubeSats such as propulsion systems and aerobrakes. Up to 50 CubeSats will be launched together to low earth orbit.  Due to atmospheric drag, the orbits of the CubeSats will decay and progressively lower and lower layers  of the thermosphere will be explored without the need for on-board propulsion, perhaps down to 200 km. QB50 will be among the first
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Photonic Integrated Circuits on InP technology plAtform enaBling low cost metro netwOrks and next generation PONs' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Cloud applications, 5G and IoT are pushing modern networks over the edge to satisfy the stringent high capacity and low latency demands. Photonic integration is a key enabling technology to tackle the new challenges and to bring new products and services to the market. PICaboo will develop novel building blocks on the InP PIC platform of TUe and III-V Lab based on the generic foundry model aiming to enhance PIC performances and reduce development costs. It will develop compact models of the building blocks and will compile them in PDK-compatible libraries allowing designers to explore their use in a wide range of applications hence maximizing their exploitation potential. PICaboo PIC demonstrators will transform the optical metro and access networks in terms of speed, footprint, power consumption and cost. The high speed EAM-based transmitters will employ all-optical equalization functionality on-chip which will scale PON line rate to 50/100Gb/s reducing the electronic signal pre-processing required for meeting the 29dB power budget of the optical distribution network within the expected dispersion limit. Both single EAM-MZM and coherent EAM-IQM transmitter PICs will leverage power consumption benefits of 50 and 65% respectively compared to 50G EML solutions and overall cost reduction by almost 20%. The dual polarization coherent receiver PIC employs integrated reset-free phase and polarization control allowing for complex DSP functions to be performed directly at the optical domain. In this case, power consumption reduction of more than 30% with concurrent cost benefits 3.6x will be achieved compared to standard coherent transceivers stemming from the use of simplified direct detection DSPs and low-cost tunable lasers, making PICaboo an attractive technology within the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Disrupting fine chemicals manufacturing with catalyst-coated tube reactors' to be submitted under Horizon 2020.

assistant: **Abstract**

Stoli Catalysts Ltd is an innovative UK award-winning innovative SME, a spin-out of University ofWarwick (UoW). Our team comprises of leading academics in the field of reaction engineering andcatalysis led by CEO with significant commercial experience and supported by two industrial experts.Stoli Catalysts patented catalyst coating technology has the potential to halve the manufacturing costsacross the Fine Chemicals industry. It delivers high mass and heat transfer rates in reactions providinghigher reactor utilization and efficiency promising to disrupt this industry.Stoli Catalysts’s coating technology can be applied to a wide range of catalysts covering more than 90%of the needs of fine chemicals industry. The initial addressable market of €317 M comprisesmanufacturers of fine chemicals (nutraceuticals, agrochemicals & speciality chemicals).Professor Evgeny Rebrov (founder) was awarded with 2 ERC grants, totalling €1,400,000, to develop,validate, perform the feasibility study and demonstrate the market potential of his ground-breakingtechnology: ERC Starting Grant 279867–RFMiFiCS “RF-enhanced micro processing for the fine chemicalssynthesis using catalysts supported on magnetic nanoparticles” and ERC Proof of Concept693739–MiCARF “Multi-tubular Catalytic Reactor for Flexible Production of Fine Chemicals”.Stoli Catalysts was supported to date by the Business Ready program of the UoW Science Park andfunding from Innovate UK, Warwick Ventures, Mercia Technologies PLC as well as from direct productsales, in-kind contribution from industrial partners (DSM and Vapourtec) and consultancy projects.The two ERC projects brought the innovation to TRL 7, and after obtaining promising results from thefeasibility study, we are applying for the SME Instrument PH2 funding to scale
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Xenopus axis determination - control of the spatial expression of the siamoishomeobox gene' to be submitted under Fourth Framework.

assistant: **Abstract**

The aim of this project is to elucidate some of the molecular mechanisms that underlie the early definition of dorso-ventral axis in vertebrates, using Xenopus as a model system. The Nieuwkoop Center (NC), located in the dorsal-vegetal cells of blastulae, constitutes the first organizing center during embryogenesis and it is defined by the relocation of maternal of dorsal determinants. It acts by inducing Spemann's organizer in the overlying mesodermal cells. In spite of its central role in dorso-ventral axis formation, the mechanisms involved in the definition of the NC are unclear. This project proposes to tackle this issue by studying the spatial regulation of Siamois, a homebox gene expressed in the NC. After cloning the genomic sequences of Siamois, we will define the cis regulatory elements present that are important for its spatial expression. Once determined, it will be possible to purify the maternal determinants that bind these sequences.