RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Intelligent MIcrorobot POweRed by Ultrasound' under Horizon 2020.

assistant: **Concept**

Microrobots with the ability of sensing physiologically important signals and respond by autonomously accumulating at target sites may revolutionize minimally invasive medicine. Miniaturizing electronic sensors, actuators and batteries to microscale is not feasible with the state-of-the-art technology. A promising alternative for instantiating on-board sensing and computation for remotely powered micromachines is exploiting structure and material properties. Recent studies show that micromachines can transform acoustic waves into controllable motion and powering can be realized using off-the-shelf medical ultrasound transducers. The objective of IMIPORU project is to develop the first truly autonomous microrobots powered by acoustic streaming (acoustically generated steady flow) that can perform taxis behaviour. To achieve this task, I will systematically study fluid-structure interaction (FSI) at the microscale numerically, experimentally and analytically. This analysis will lead to the design of novel mechanisms that respond to varying hydrodynamic loads. By manifesting mechanical instabilities, robots will mimic flagellated bacteria that exploits the buckling of the hook to change direction. Furthermore, understanding FSI is instrumental for optimizing the acoustic propulsion machinery. State-of-the-art, high-resolution two-photon polymerization technique for photocurable polymers will be used to manufacture multi-material structures with complex geometries. Since acoustic actuation does not depend on material choice, integrating responsive soft hydrogels into the structure will add another dimension for interacting with the environmental via chemical and temperature signals. Incorporating intelligent mechanical design along with responsive materials will enable micr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on '“EPIgenetic impacts on early-stage SPECiation and adaptive radiation”'.

assistant: **Concept**

Phenotypic plasticity plays a key role at the onset of the speciation process, facilitating diversification though the induction of novel phenotypes in response to distinct environments. Via genetic accommodation and genetic assimilation, this influence may extend throughout the speciation process and beyond, into subsequent speciation events. While the epigenetic regulation of gene expression that mediates phenotypic plasticity has been extensively studied in lab-based model organisms, very little is known about epigenetic variation in natural populations. This project will be the first epigenetic study explicitly focused on the speciation process. Using cutting-edge techniques, the applicant will characterize DNA methylation variation within and among the sympatric species of a recently discovered endemic cichlid fish radiation in Lake Massoko, Tanzania. Specifically the applicant will test: if 1) newly formed species differ in the distributions of epigenetic marks across the genome, 2) genomic variants linked to phenotypic divergence among species are in genomic regions unusually high in DNA methylation, as expected under a hypothesis of epigenetic differences preceding fixed nucleotide differences during adaptive divergence, 3) genomic regions diverging in patterns of methylation among incipient species are also exhibiting high levels of methylation in populations of Astatotilapia calliptera, the ancestral, colonizing species. The results of this pioneering project will provide the first empirical evidence of the importance of epigenetic variation during the emergence of new species.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Tropical Differential Geometry'.

assistant: **Objectives**

The all-pervading utility of differential equations, and therefore of methods for their solution, in mathematics and the physical sciences, especially in mechanical and electronic engineering, is undisputable.  The heat and wave equations are star examples. The subject has a long history, including its interactions with modern algebra since it was brought into that framework by Ritt in the late 1930s.Tropical geometry, introduced two decades ago, is a rapidly developing area of mathematics offering a new approach to algebraic and geometric problems, for instance, counting solutions to equations. ""Tropicalising"" these problems turns them into new problems stated only in terms of ensuring that collections of linear functions are tied for the greatest value, which have the same answers as the originals but can often be easier to solve.In 2015, the Fellow and others introduced an application of tropical tools to differential algebra. Inspired by the initial successes of these methods, we are here proposing to extend them to classes of differential equation not yet handled,to bring more algebro-geometric machinery to bear, to transfer further aspects of the theory of tropicalisation of algebraic varieties to differential algebra, and to extend the computational algebra which motivated Grigoriev's interest to our new settings.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Paediatric Medical Trust' (PMT) under Seventh Framework.

assistant: **Objectives**

The Paediatric Medical Trust fellowship is a multidisciplinary collaboration between a post-doctorate student from Italy (Dr. Petrocchi) in Clinical Child/Developmental Psychology and academics/practitioners from the UK in Psychology (Professor Rotenberg, Dr. Sargeant), Paediatric Medicine (Professor Lenny), Health and Rehabilitation (Dr. Rimmington), and the Asthma UK Health Organization (Ms. Versnel). The academics/practitioners have expertise in interpersonal trust, paediatric illnesses, and research methods. The purpose is to: (a) provide paediatric medical psychology training to the post-doctoral student to establish her career in that field, (b) obtain qualitative and quantitative research findings regarding the effects of interpersonal trust and other psychosocial factors on the treatment of children with serious illnesses, (c) redress the scarcity of professionals in Paediatric Medical Psychology, (d) establish guidelines for establishing and maintaining trust in the treatment of children with serious illnesses, and (e) redress the problem of non-adherence to prescribed medical regimes by children with serious illnesses. The fellowship is the first comprehensive and quantitative examination of the role that interpersonal trust plays in the treatment of children with serious illnesses and to develop evidence-based guidelines for establishing that trust. The qualitative study will comprise interviews or focus groups with children with asthma, children with diabetes, their parents and their paediatricians/physicians. The quantitative study will comprise an 8-month longitudinal study of 135 children with asthma. It will examine the extent to which children’s and parents trust beliefs in physicians and other psychosocial factors predict children’s adherence to prescr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Origami inspired thermoelectric generators by printing and folding' (ORTHOGONAL) under Horizon Europe.

assistant: **Objectives**

The transition towards an energy-sustainable society is the key challenge for the engineering sciences in the 21st century. This proposal addresses the energy supply for the future trillion sensor devices that form the backbone of our digitized society and it addresses the possibility to recover huge amounts of low-temperature waste heat in industry. Energy-harvesting from low-temperature environmental heat via thermoelectric generators (TEG) is a versatile and maintenance-free solution for both challenges. A prerequisite, however, is a cost-effective and scalable materials and manufacturing strategy for such TEGs. ORTHOGONAL will explore the devices using novel printable thermoelectric nanocomposite materials and it will tackle the fabrication challenges of printed TEGs based on ultrathin (< 2 µm) polymeric foils. We will explore n-type and p-type inorganic printable nanomaterials with high efficiencies and will use them for large area 2D printing on ultrathin substrates. By using photonic sintering, we will nano-solder the thin TEG films. The TEGs will then subsequently be fabricated by an origami-inspired folding process. A customized machine will be designed and constructed to allow for an automated folding of the 2D foil into the desired 3D geometry. As demonstrators, the project will realize TEG powered autonomous sensor nodes and a heat exchanger including a large area TEG. The work will build on my more than 30 years of experience in solid state semiconductor devices, several key patents from my group, and our recent proof-of-concepts for the thermoelectric materials and the device design. The design and fabrication principles of ORTHOGONAL will also be of use of other large-area electronic devices, e.g., X-ray detectors, THz-metamaterials, and piezoelectric tra
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Carbonitride Metal Navigator'.

assistant: **Objectives**

The CarMeN (Carbonitride Metal Navigator) project aims to revolutionize the discovery of functional materials by combining machine learning (ML) with crystal structure prediction (CSP) to accelerate exploration of the vast and underexplored space of metal carbonitrides (MCNs). MCNs, composed of earth-abundant metals with carbon and nitrogen, exhibit exceptional mechanical, electronic, catalytic, and superconducting properties, making them highly relevant for sustainable energy, catalysis, quantum technologies, and advanced manufacturing. Despite this promise, only a small fraction of MCN compounds has been studied due to the limitations of conventional density functional theory (DFT) methods.The project overcomes these bottlenecks by developing machine-learned potentials (MLPs) trained on high-quality DFT data, achieving near-DFT accuracy at orders-of-magnitude lower cost. These MLPs will enable high-throughput CSP, systematically mapping stable and metastable MCN phases while incorporating multi-objective optimization to identify compounds with technologically desirable properties. Predicted structures will be rigorously validated through phonon stability checks, property calculations (mechanical, electronic, catalytic, and energetic), and synthetic pathway analysis, ensuring experimental feasibility.The methodology is structured across five work packages: (i) project and data management under FAIR principles, (ii) MLP development, (iii) ML-accelerated CSP, (iv) property evaluation and synthesis-informed validation, and (v) dissemination and open science practices. By uniting interdisciplinary advances in machine learning, computational chemistry, and materials science, CarMeN will establish a scalable discovery paradigm that bridges theoretical prediction and practica
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Networking and Integration of National Programmes in the Area of Wood Material Science and Engineering' (WOODWISDOM-NET) targeting Sixth Framework.

assistant: **Abstract**

The development of sustained cooperation between the national research activities in the area of wood material science will enable the development of new innovative, eco-efficient, cost-competitive prod-ucts, processes and services and thus promote the competitiveness and sustainability of European for-estry and forest-based industry. At present, European research resources in the area of wood material science are scattered in the form of a number of uncoordinated activities. There are highly specialised research groups in wood material science especially in wood rich countries, but the coordination at European level is missing. Since re-search priorities are set independently by the involved actors there is no systematic approach to achieve complementarity. Sustained collaboration between key research funding and managing organisations is needed to enable broader strategic analyses as a basis for management decisions, and could also for-ward a more efficient implementation of research results. The main activities of the WOODWISDOM-NET are: Building an information exchange system (research programmes) "Benchmarking and dissemination of good practices "Identification of complementary research activities "Identification of practical networking and opening mechanisms for future cooperation "Implementation of joint evaluation and foresight activities "Implementation of transnational research programme to improve competitiveness and sustainability of the forest cluster. In the WOODWISDOM-NET consortium are participating 18 partners from 8 countries."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Dynamic Peptide-Phosphate-based Hydrogels for Modelling Diseases and Therapeutic Interventions' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Supramolecular biomaterials represent a promising solution to address complex challenges in advanced therapies and disease modelling platforms. D-PhosMate’s overarching aim is to explore different formulation strategies and molecular designs based on enzymes, natural phosphate-containing units, and peptide amphiphile building blocks, to generate self-assembling hydrogels with time-dependent mechanical and degradation properties as vehicles for the delivery of living therapeutics (generated in situ) and in vitro extracellular matrix models along disease progression. These biocompatible hydrogels will exhibit enzyme-instructed biomechanical and chemical tuneability, which represent versatile platforms that will be leveraged for two applications. First, for the post-operative treatment of glioblastoma multiforme (the most aggressive malignant brain tumour), and second, for understating the molecular mechanisms responsible for ectopic calcifications (the mineralisation of the extracellular matrix of soft tissues like kidneys, joints, heart valves, and arteries, among others).Outcomes from the project will benefit several communities, including peptide and supramolecular chemistry, biomaterials science, bioengineering, cancer, and cardiovascular medicine, among others. All of this, while providing advanced training and career development opportunities for a young researcher at the intersection of advanced biomaterials design, peptide nanotechnology, and precision medicine. Molecular tools provided by D-PhosMate will increase available cancer therapeutic choices and will contribute to improving the translation of preclinical research, enhancing success rates of clinical trials (with a consequent multibillion-dollar impact) and the life quality improvement of patients in need
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Marie-Curie grant on primary Immuno-deficiencies and Auto-Immune diseases' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Primary immunodeficiency diseases are rare congenital conditions. They represent an experiment of nature, demonstrating the importance of specific genes and proteins in the host defence against pathogens. In primary immuno deficiencies the susceptibility to infections often goes along with the development of autoimmune conditions. In the most prevalent human primary immunodeficiency requiring medical attention, termed Common Variable ImmunoDeficiency (CVID), the prevalence of autoimmunity is approximately 25%. Mutations in the TNF-like B cell receptor TACI, which is expressed in the germinal centre in secondary lymphoid organs, account for up to 10% of the CVID cases.In TACI deficiency, lymphoproliferation is observed in 2/3 of the patients and autoimmune conditions in approximately 1/3 of the patients. The ligand of TACI, termed BAFF, has been shown to take a centre stage in common human autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus. In addition to TACI, BAFF binds also to BCMA and BAFF receptor. Which of these receptors however, contribute to the development of autoimmunity has not yet been studied.This Marie-Curie application now would like to extend the applicant's findings in TACI deficiency in CVID to other disease entities and would like to address the role of TACI in autoimmunity and ultimately address the hypothesis that some patients with an antibody deficiency syndrome may in fact suffer from an autoimmune condition in which the antibody producing cells ar e the target of autoimmunity.This hypothesis is supported by following observations:1. TACI-knockout mice suffer from an SLE-like autoimmune condition2. Lymphoproliferation is observed in two thirds of patients with TACI and one third have an overt autoimmune disease3. Au
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Micro- Multi-Material Manufacture to Enable Multifunctional Miniaturised Devices' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

For some decades the world has been able to see the ultimate impact of device miniaturisation which has led to dramatic growth in national and global revenues alongside the huge benefits that have been brought to human activities, in the healthcare/medical, energy, space, transport, communication and defence sectors. Evolving initially from silicon based manufacturing technologies thanks to the huge investment and established infrastructure, current state-of-the-art play in moving further according to the “More than Moore” has substantially extended the global capacity in achieving complex microsystem integration using hybrid processes, multi-materials that are significantly confined in an ever small space or dimensions. The challenges in the endeavour of continuous miniaturisation therefore exist in the fundamental understanding of the phonemes behind all the play,in order to underpin a paradigm of future generation miniaturised device. With significant developments for some decades the various capabilities and expertise bridging the EU and Asia are now available to readily forge a tangible strong consortium targeting such an important field. Given its inter-disciplinary nature, the project will cover a wide breadth of research topics as demanded through collaborations and researchers’ mobility provided by International Research Staff Exchange Scheme as one of the Marie Curie Actions to draw the strength from the representative institutions in Germany, Japan, China and UK. The project will focus on the potential challenges and potential issues encountered in the integration of miniaturised devices in terms of novel materials and processes, characterisation and testing, demonstrating the manufacturability and reliability. Both experimental and computational approaches w