RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Unveiling dynamics and substrate interactions of large protein complexes by NMR spectroscopy' (NMRofLargeComplexes), addressing dissemination and exploitation.

assistant: **Impact**

Dynamic properties of proteins are essential for their function. NMR can reveal protein dynamics in solution on a broad range of timescales and at atomic resolution. However, NMR studies of large proteins remain challenging since conventional NMR methods are constrained to small proteins. The aim of this project is to extend the NMR size limit to large protein complexes by combining recent developments in site-specific labeling schemes with novel NMR methods employing state-of-the-art spectrometers. This will facilitate the study of functionally essential but so far uncharacterized dynamics and substrate interactions of two large protein complexes, providing unprecedented insight into the relationship between dynamics, structure and function. Since most proteins are dynamic, extending the scope of protein complexes that are amenable to NMR study is of great interest to many areas of molecular biology. Studies will be conducted on the eukaryotic exosome, a 370 kDa soluble, asymmetric decamer involved in RNA degradation and processing, and the 80 kDa Na+/H+ antiporter NapA, an integral membrane dimer involved in ion transport. For the exosome, individual subunits will be 13C-methyl labeled; the employment of sophisticated NMR methods will then permit the detection of functionally essential dynamics and RNA-substrate binding patterns of the exosome. As NapA is a low-yield membrane protein, an inexpensive 19F-labeling approach will be employed to reveal global transport dynamics and local gating motions. Exosome production and all NMR experiments are to be conducted in Remco Spranger’s lab at the University of Regensburg, Germany. NapA will be produced during a secondment in David Drew’s lab at Stockholm University, Sweden. This newly established international collaboration
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Embracing Immigrant Knowledges for Just Climate Health Adaptation' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Climate change, human health and immigration are arguably the most prominent, enduring, and challenging issues of our times, with important implications for justice. Studies on the nexus of these issues have largely focused on climate change as posing challenges to health and thus acting as a push-factor for migration. However, our understanding of how climate is impacting the health of immigrants in places of migration destination is still poor. Further limiting our understanding of potential climate and health injustices, immigrant communities in Europe are far from homogenous, and are often racialized groups of great ethnic diversity. With IMBRACE, I examine what shapes immigrants’ climate health vulnerability and how their situated knowledges and practices can inform both their own response capacities and urban climate adaptation more broadly, towards more effective and just approaches. I focus on two types of climate impacts, chosen as most relevant for urban areas in Europe and with important implications for health: (a) increased and prolonged heat, and (b) intense rainfall and flooding. I employ a pioneering feminist political ecology approach that combines participatory ethnography, critical discourse and policy analysis, and transdisciplinary knowledge production. Focusing on 6 case-study cities in Europe– I systematically explore tangible and intangible factors and structural drivers of immigrants’ climate health vulnerability, centering and engaging with immigrants as expert knowledge-holders. Mobilizing knowledge that comes with and through immigration, I offer an intersectional justice perspective that considers class, gender, race, ethnicity, and other axes of power and oppression when designing and assessing urban climate and health adaptation policy. Th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Three-Dimensional Perovskite Oxides as Working ElectRochemical devices' (3D-POWER), addressing dissemination and exploitation.

assistant: **Impact**

Three-Dimensional Perovskite Oxides as Working ElectRochemical devices (3D-POWER) will focus on utilization of perovskite oxides in combination with functional metallic materials to address the specific demands of sustainable energy sector. The so formed 3D structures will serve as promising electrodes for the development of electrochemical devices such as solid oxide fuel cells, electrolyzers, batteries and supercapacitors. Specifically, within this project atomically layered perovskites including La1-xSrxCo1-yFeyO3 (LSCF) and La1-xSrxMnO3 (LSM) will be synthesized through pulsed laser deposition and/or molecular beam epitaxy on pre-designed 3D substrates of Copper or Iron depending on growth conditions of perovskites and eventual applications of the electrodes. These substrates will be uniquely fabricated by nanoscribe printing of metals to cast a 3D scaffold like support for the growth of perovskites and later will be chemically etched off. Further, the performance of these perovskite constructs will be enhanced by depositing highly functional transition metal dichalcogenides (TMDs). This will serve as interconnects due to their excellent electrical, chemical and physical properties and overall enhance device’s catalytic activity.The custom designed formation of electrodes proposed in 3D-POWER will address the critical issues like reproducibility, low gravimetric density, and long range conduction. Innovative combination of perovskites in 3D scaffold architecture with the functional TMDs will propel new pathways for high performance electrochemical devices for energy storage and conversion. Through 3D-POWER I will utilize Imperial’s advanced cutting edge technology and develop relevant applications with Prof. Skinner’s multidisciplinary team that have an excellent tr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Demonstration of a biologically sustainable and environmentally hgh precision thermal seed treatment method'.

assistant: **Objectives**

The overall purpose is to present a new, innovative seed treatment method, partly build on the old way of seed treatment by hot water, for diseases sanitation of seeds. The new, successful idea can be described as heat treatment by high precision without any need of drying the seeds after the process. It is competitive to ordinary chemical seed treatments in terms of both efficacy and commercial potential as showed in pilot tests. The idea presented is regarded as promising for successful commercialisation, but before private investments will be done, there is a great need to demonstrate the efficiency of this new technology in field experiments in different countries to receive international acceptance. There is also a need to evaluate some biological parameters more sharply and to test and validate the effect of the method on a varying plant material and in different climate zones of Europe. The project, a co-operation between biological, engineering and commercial partners, is aimed at conducting the experiments needed and to bring this new technology to the market (farmers, cooperatives, seed companies etc.). The objectives of this demonstration project are: 1. to demonstrate a new environmental friendly and economically sustainable seed treatment method for controlling seed borne diseases of cereals and rice. 2. to support the European agriculture in reducing the use of pesticides. 3. to rise the knowledge about, and to speed up the adoption of the new treatment method in Europe. 4. to encourage EC industry, by disseminating deliverables and results, to develop prototypes and to commercialise the technical systems to make them available for practical use. 5. to increase the scientific knowledge about seed sanitation by heat treatment, which will be the basis for an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Neurocognitive comparison of speech and music processing' (1998-2002).

assistant: **Innovation**

As the supervisor of Dr. Tervaniemi's doctoral thesis and as the head of the Cognitive Brain Research unit, I would like to state the following: Dr. Tervaniemi has worked at the Cognitive Brain Research Unit of the University of Helsinki since June 1990 as a research secretary, graduate student, research fellow, and coordinative researcher of an EU-project. During these years, she has investigated the neural basis of auditory sensory memory by using electroencephalography (EEG) and magneto encephalography (MEG). In addition, she has been actively involved in positron emission topographic (PET) studies. Her research topics cover the fine-grained temporal discriminative functions and temporal integration of auditory information, musical pitch and timbre, elements underlying speech perception, and the different levels and type of musical training and aptitude. In addition, she has contributed to the development of several clinical applications based on the event-related potential (ERP) called the mismatch negativity (MMN). These efforts have resulted in more than 30 publications in international peer-reviewed journals and several talks in international seminars and congresses (including 4 invited talks). In her research, she has successfully transferred and integrated knowledge from several scientific fields into meaningful research questions and, by using optimal paradigms and methods, then experimentally approached them in a highly productive manner. Besides being active in research, Dr. Tervaniemi has taken responsibility in the financial administration, congress organization, and supervision of master's and doctoral theses at the Cognitive Brain Research Unit. Also in these tasks she has been open-minded, creative, and persistent in achieving the predetermined goals. T
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Efficient Grid Connected Buildings: A Distributed Control Framework for Managing Flexible Loads' (BuildingControls).

assistant: **Concept**

The renewable energy penetration targets set by EU  and US  necessitate a radical change in the way we operate the electric power grid. Conventional power grid was designed around dispatchable central power plants at a transmission level providing services down to industrial, commercial and residential end-users at a distribution level. Increased penetration of the intermittent and uncertain renewable energy sources effectively implies additional load and generation flexibility is required at multiple time-scales to ensure safe and stable operation of the electric grid. Since conventional generation is increasingly displaced by renewables, this additional flexibility can no longer be sourced solely from conventional plants. According to the International Energy Agency, buildings are responsible for about 40% of the global energy consumption, and about 50% of the energy used in a building is accounted for by the heating, ventilation and air conditioning (HVAC) system. Thus, improving operational efficiency of HVAC systems will results in large savings in the energy consumption. Moreover, buildings present a unique opportunity as flexible loads that can be controlled to provide ancillary services to the electric power grid, and thus enable high penetration of renewables.  High thermal capacity of large commercial buildings allow real-time control of their HVAC systems to regulate electricity demand as required for grid stability, without effecting the quality of service in the building significantly.In this project, our objective is to develop (1) novel scalable optimal control algorithms that reduce building peak load and energy consumption, (2) a distributed control framework for coordinating multiple buildings as flexible energy resources for ancillary services, and (3
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Investigating the role of oxidative stress or diet on prion disease susceptibility' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

PrPc binds copper and has antioxidant activity enhancing the survival of cells in culture, suggesting that PrPSc accumulation may lead to an aberrant copper metabolism altering the cellular redox state. This proposal centres on understanding to what extend PrPc expression, and susceptibility to prion can be influenced by oxidative stress. In vitro studies with murine neuroblastoma N2a and Schwann MSC80A cells, and in vivo studies with transgenic mice over expressing either mice, human or bovine PrPc, under normal conditions or after various treatments (irradiation, hypoxia, Cu depletion and Mn feeding, ingestion of phosmet) known to cause oxidative stress, will show if and to what extent these stress situations may enhance PrPc expression and the susceptibility to prion infection. The work will also contribute to the basic understanding of PrP and may give information or cellular tools (new chronically infected non neuronal cell model) that could benefit treatment.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Efficient System for Flow Control Actuation' (FLOCOSYS) targeting Seventh Framework.

assistant: **Abstract**

Flap systems are highly efficient lift providing elements in low speed flight. A potential measure to shift the stall onset to higher limits can be found in an Active Flow Control (AFC) approach by pulsed blowing. The majority of corresponding research aims at understanding the aerodynamic phenomenon allowing broad bandwidth investigations to find optimum configurations. In this proposal the systems aspects are addressed with respect to the active flow control actuator system. The overall system integration will be performed by the SFWA partner EADS-IW with support provided by TUB through this project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'From Real-world Identities to Privacy-preserving and Attribute-based CREDentials for Device-centric Access Control'.

assistant: **Objectives**

ReCRED’s ultimate goal is to promote the user’s personal mobile device to the role of a unified authentication and authorization proxy towards the digital world. ReCRED adopts an incrementally deployable strategy in two complementary directions: extensibility in the type and nature of supported stakeholders and services (from local access control to online service access), as well as flexibility and extensibility in the set of supported authentication and access control techniques; from widely established and traditional ones to emerging authentication and authorization protocols as well as cryptographically advanced attribute-based access control approaches. Simplicity, usability, and users privacy is accomplished by: i) hiding inside the device all the complexity involved in the aggregation and management of multiple digital identifiers and access control attribute credentials, as well as the relevant interaction with the network infrastructure and with identity consolidation services; ii) integrating in the device support for widespread identity management standards and their necessary extensions; and iii) controlling the exposure of user credentials to third party service providers. ReCRED addresses key security and privacy issues such as resilience to device loss, theft and impersonation, via a combination of: i) local user-to-device and remote device-to-service secure authentication mechanisms; ii) multi-factor authentication mechanisms based on behavioral and physiological user signatures not bound to the device; iii) usable identity management and privacy awareness tools; iv) usable tools that offer the ability for complex reasoning of authorization policies through advanced learning techniques. ReCRED’s viability will be assessed via four large-scale realistic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Regulation and function of non-coding RNAs in epigenetic processes: the paradigm of X-chromosome inactivation'.

assistant: **Innovation**

Some 150 years after the emergence of genetics, epigenetic mechanisms are increasingly understood to be fundamental players in phenotype transmission and development. In addition, epigenetic alterations are now linked to several human diseases including cancers. A common feature of many epigenetic phenomena, for which X-chromosome inactivation (XCI) is the paradigm, is the implication of non-coding RNAs (ncRNAs). Regulatory ncRNAs belong to 2 major classes: (i) long ncRNAs, which can be transcribed from a single strand as well as in the opposite orientation when they may overlap with either protein-coding or non-coding genes. Both sense (Xist) and antisense (Tsix) ncRNAs control the initiation of XCI; and (ii) short ncRNAs, such as si- or miRNAs, which interfere, through different pathways, with gene function. The aim of this project is to gain insights into the regulation and function of ncRNAs in the control of gene expression program, using XCI as a model system. We propose to combine molecular genetics, embryology and cell biology to (1) decipher the transcriptional control of Xist and the coordinate regulation of the Xist/Tsix sense/antisense tandem in relation to developmental programs; (2) functionally characterise a novel ncRNA on the X chromosome which nests several miRNAs and for which preliminary data suggest a role in XCI and (3) develop a system to extend our knowledge of the regulatory stages of XCI in human through the use of human embryonic stem cells. Our comprehensive analysis of the function and regulation of ncRNAs in XCI has important implications for our understanding of the numerous diseases associated with abnormal patterns of inactivation and is a critical prerequisite to any subsequent therapeutic approaches. This project is in absolute adequac
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Optimal design of multi-functional ventilated facades' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

A Multi-Functional Ventilated Facade (MFVF) is an assembly of modules, of about I to 3 meters width and one or two storeys high, with two layers of different materials separated by a vertical air channel. They can be uniform but they usually have different zones, like a transparent zone and an opaque zone. They are pre-fabricated and then assembled in the same building. l-Goal of the project The goal of the project is to design and test optimal MFVF, conceived for different climates in Europe (southern, central and northern) in order to improve the buildings in two aspects: -Better passive behaviour (reduction of the cooling / heating / lighting energy -Better indoor living and working conditions In order to permit the construction of facades tailored to different applications of the buildings, spatial orientations and climate areas, as well as to the refurbishment of existing buildings, different modules will be investigated. 2-Results of the project -A set of optimal MFVF prototypes conceived for specific climates (southern, central and northern) in Europe -A detailed study of the optimal modules -Prototypes with experimental results (in test cells and in real buildings) -Detailed numerical simulations of the modules -A description of the facades for different architectural requirements and types of construction -Experimental facilities and extensively validated numerical models that will allow the design of optimal MFVF modules in situations not foreseen in this project. 3-Overview of the project The project is divided in to 13 Tasks and will be carried out in 30 months. The tasks can be classified in two stages: Stage A-Enhancement / validation of numerical models The partners have already developed codes for the detailed numerical simulation of MFVF. Before their a