RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Demonstration of innovative integrated biomass logistics centres for the Agro-industry sector in Europe' (AGROinLOG).

assistant: **Concept**

The main goal of AGROinLOG is the demonstration of Integrated Biomass Logistic Centres (IBLC) for food and non-food products, evaluating their technical, environmental and economic feasibility. The project is based on three agro-industries in the fodder (Spain), olive oil production (Greece) and cereal processing (Sweden) sectors that are willing to deploy new business lines in their facilities to open new markets in bio-commodities (energy, transport and manufacturing purposes) and intermediate bio-products (transport and biochemicals). These sectors represent over 10% turnover of agro-food industries and 30% of those with inherent synergies to integrate food and non-food business taking advantage of their existing equipment, seasonality and established food logistics. The synergies of applying IBLCs business in existing agro-industries can have a positive impact over 18% in final product price, giving a clear competitive strength to a wide segment of agro-industries, which can exploit this privileged situation compared to a new biomass supply business built from scratch.The project is built on these agro-industries that will achieve a TRL7-8 in their facilities, guaranteeing operation under real conditions and with big amounts of production compared to the current activity, ensuring proximity to real market at the end of the project. Main challenges are based on being able to integrate logistics, harvesting and equipment in food and non-food applications, where the project is focused; ensuring marketability of the final bio-commodities. Besides, AGROinLOG will apply a multi-actor approach to attain experiences and knowledge of the sectors and agro-industries, enhancing the accuracy of the business models and developing effective and friendly guidelines of best practic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Connectionist methods for preprocessing and analysis of remote sensing data.'.

assistant: **Innovation**

This is a concerted action on the theme of connectionist (neural network) computing methods in satellite remote sensing. It concerns the roles of connectionist computing both in routine operations concerned with preprocessing remotely sensed data and ancillary data sets, and in subsequent data analysis which is more application-specific. The primary objectives of the activity are to: (a) assess progress to date throughout the European Union (and elsewhere) on the application of neural or connectionist computing in remote sensing (b) evaluate the potential benefits to be derived from pursuing further researc and development on this theme in a coordinated manner (c) to draw up an appropriate research agenda for the future taking into accoun the results and conclusions of (a) and (b). These objectives will be met by carrying out two principal activities: (i) holding an open European workshop on connectionist computing in remote sensing (ii) holding a concertation meeting to evaluate the results of the workshop and to set future research priorities and to draw up an appropriate research agenda. In order to ensure that all relevant national activities are taken into consideration, a national point of contact" will be used in each member state of the European Union to identify existing national projects and experts. KEYWORDS(maxlO): REMOTESENSING, NEURAL NETWORKS"
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'DYnamical drivers, predictability and trends  of compound CLimate EXtremes' in the context of a Horizon Europe call.

assistant: **Objectives**

Different climate extremes often interact and the resulting events, termed compound extremes, can lead to amplified socioeconomic impacts. Gaining a deep understanding of compound extremes is highly societally relevant and of key scientific importance for understanding climate risks. However, compound extremes are inherently multivariate and rare, which poses a daunting challenge to current scientific approaches.My aim in DYCLEX is to provide a radically new perspective on the drivers, predictability and trends of compound climate extremes. I will ground this in a physical and statistical understanding of how the large-scale atmospheric circulation modulates compound extremes. My focus will be on the co-occurrence, at the same or at remote locations, of mid-latitude surface temperature, precipitation and wind extremes.To achieve this ambitious aim, DYCLEX builds on key contributions from my own research and that of my research group, partly issued from my previous ERC project. Specifically, DYCLEX exploits my cutting-edge work on atmospheric dynamics, dynamical systems theory, statistical analyses and machine learning for the study of extreme events. I will use this interdisciplinary knowledge base to detect and quantify compound climate extremes and elucidate their link to different large-scale atmospheric circulation features. I will then leverage this to identify new predictability pathways for the compound extremes and to explain their long-term occurrence trends. The analysis framework I will develop is a flexible tool, applicable to a wide range of multivariate extremes in the Earth system and beyond.DYCLEX is timely: Climate risks and extremes feature prominently in two Lighthouse Activities of the World Climate Research Programme, as well as in the EU’s strategy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Gain by Strain: Precise Cuts of Cyclopropanes as Key to Molecular Complexity' (GAINBYSTRAIN) under Horizon 2020.

assistant: **Objectives**

A central discipline of chemistry is the design und creation of molecules with defined structural and chemical properties. Stretching synthetic horizons is a never-ending endeavor to inspirit the chemist’ s creativity in preparing compounds and materials yet to be discovered. Relying on their high strain energy cyclopropanes, as carriers of the most fundamental ring geometry, offer a unique reactivity which allows for a multitude of transformations being grouped in ring-opening reactions, cycloadditions and rearrangements. Major advantage of all these processes is the cyclopropane-derived intrinsic atom-economy.In this research project, we propose a number of uncommon and challenging reactions making use of donor-acceptor cyclopropanes. Introducing a distinctively controlled bond cleavage we seek to develop novel modes of 1,3-bifunctionalization by σ-bond metathesis, by using hypervalent iodine reagents and by merging organocatalysis with photoredox catalysis. Unprecedented ring-enlargements to four-membered rings by [3+1]-cycloadditions employing isonitriles, carbenes and nitrenes are envisioned, aryne insertions into the three-membered ring leading to indane systems are planned and a general concept for [3+3]-cycloadditions with 1,3-dipoles is presented paving the way to unusual syntheses of heterocycles.A distinct class of compounds obtainable by our methodology will set the stage to access completely unexplored heterocyclic π-systems being of interest for material science and molecular electronics.Besides our central goals of advancing organic methodology and to demonstrating the synthetic utility of these novel reactions, we anticipate that mechanistic insights gained by experimental and computational means will be of high impact for the chemistry of this fundament
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'NEUROMOPHIC SYSTEMS BASED ON MEMRISTOR AND FERROELECTRIC DEVICES FOR COMPUTING APPLICATIONS' under Horizon Europe.

assistant: **Concept**

Artificial neural networks (ANNs) are simplified models and hardware that simulate how the brain of living beings, especially humans, process information. ANNs are inspired by the nervous system and biological behavior, creating a layered interconnection system of artificial neurons that collaborate to process input data and generate output. ANNs differ from other AI models in having the ability to learn automatically (machine learning). This technology has enormous current impact and potential for future applications, just to mention a few ones: autonomous vehicles, renewable energy, economy and financial predictions, computer visions, and disruptive medicine and health care services. In the last decade, ANNs have become a very popular topic, but the technology itself has been around for many decades with several problems yet to be solved. For example, current computer systems are highly inadequate in terms of data processing, storage and transmission. Aspects related to energy consumption are also an unsolved problem, where the rational use of energy and natural resources is a fundamental objective of global sustainability. NEMERFEC aims to realize novel ANNs through the development of hardware based on memristive and ferroelectric material systems. Such thin films of binary and complex oxides are to be deposited by physical ablation methods, such as PLD and sputtering, with a high degree of control during deposition. Advanced characterization techniques, microfabrication and nanofabrication of devices will be performed at the clean room facilities of the Aragon Nanoscience and Materials Institute (INMA-CSIC) to obtain ANNs at nanometric scales and with an ultra-fast response time. The final ANNs will be implemented in the analysis of thermal images in hyperthermia pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Power Dynamics in Transformative Social Innovation' in the context of a Horizon Europe call.

assistant: **Objectives**

Initiatives around the world are addressiInitiatives around the world are addressing societal challenges by experimenting with social innovations (SI), i.e., new ways of doing, thinking and organising. Examples include sharing economy, eco-communities, participatory democracy and many more. Such SIs can contribute to societal transformation if/when they challenge, alter and/or replace dominant structures and institutions that underly the root causes of societal challenges. To have such a transformative impact, SIs must undergo some form of diffusion, scaling or mainstreaming. In this process, they lose (some of) their novelty and risk reproducing or even aggravating the structures/problems that they meant to challenge in the first place, thereby possibly contradicting their original intentions. This project tackles this innovation paradox from a power perspective by studying how power relations are changed and/or reproduced in processes of transformative social innovation (TSI) and asking how/to what extent SIs are/can be mainstreamed and gain power while upholding transformative potential. We develop a novel power framework that synthesises major power contestations in social and political theory to analyse how actors across different institutional logics (state, market, community, non-profit) gain/lose/exercise/undergo power in TSI. We conduct embedded case studies of 4 SI-trends (sharing economy, eco-communities, decentralised energy, and participatory democracy) at multiple scales, including 12 translocal networks and 12 local initiatives in 3 geographical contexts (United Kingdom, the Netherlands, Portugal), using interviews, participant observation, document reviews and Transformative Power Arena sessions. We design a Critical Power Moments methodology for retrosp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Cortical Microcircuits: Parvalbumin neurons Orchestrate Stress Eating' (CoMPOSE), addressing dissemination and exploitation.

assistant: **Impact**

Stress leads to enhanced food intake and a shift in dietary choices towards more high-caloric and unhealthy food. While this serves an adaptive purpose to replenish energy stores after a physical challenge, in modern society where continuous psychological stressors are present and cheap unhealthy food easily accessible, this leads to an alarming situation where many people overeat. As a consequence, obesity levels are rising with severe consequences for our health. Especially people with an eating disorder, like binge-eating disorder, are vulnerable to this situation. Human and animal studies both point to a critical role of the prefrontal cortex (PFC) in coordinating stress-induced food intake. The prefrontal cortex is a highly heterogenous structure sending coordinated neuronal output to many brain regions with opposing roles in food regulation. This indicates that these circuits are under tight regulation of local interneurons. However how interneurons coordinate circuits for stress-induced feeding behavior is not known. In this project I aim to understand how Inhibitory interneurons shape output patterns of prefrontal cortical pyramidal neurons in a projection-specific manner to drive stress-induced food intake. To this aim I will use a combination of viral tracing techniques and in vivo electrophysiological recordings of identified PFC interneurons and pyramidal neurons in mice. Moreover I will use chemogenetic approaches to manipulate specific PFC pyramidal neural circuits to understand their role in stress eating responses. This will yield important insight into the circuit mechanisms underlying this maladaptive behavior. Studying how this phenomenon arises at the level of neuronal circuits will provide evidence-based targets for prevention strategies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The role of the Drosophila tumor suppressor gene p53 in apoptosis and adhesion' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Apoptosis is a form of cell death ubiquitously used in animals, which participates in development and in the adult in defense against potentially dangerous cells. Not surprisingly, deregulation of cell death has severe consequences for the developing organism and adult. Inappropriate cell death is associated with many disorders including degenerative neurological diseases (excess of cell death) and cancer (loss of cell death). One of the important components of the cell death machinery is the p53 transcription factor. p53 is often described as the 'guardian of the genome' because it is a critical component of the cellular mechanisms that respond to genotoxic stresses like DNA damage and hypoxia to maintain the genomic integrity in part by arresting cell-cycle progression or by inducing apoptosis. In Drosophila, p53 is also involved in genome integrity maintenance and also in development. In mammals, emerging evidence shows that the contribution of the tumour suppressor p53 to the control of tumorigenesis is not restricted to its well-known anti-proliferative activities, but is extended to other stages of cancer development, i.e. the modulation of cell migration. In drosophila, several evidences are suggesting that p53 could also have additional roles and also participate in cell adhesion and/or polarity maintenance control. Our goal is to extend the investigation on p53 function in drosophila during development. We propose to follow two recent results that have been proposed in mammals: first to understand the function of p53 in the control of cell adhesion and also to study the alternative splicing of p53 in drosophila taking into consideration the recent discovery of two p53-related genes, p63 and p73 and their different isoforms. Finally we would like to address if a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Integral formulae and extrinsic geometry of foliations' (EXTGEOMFOL).

assistant: **Concept**

The project concerns investigations of the extrinsic geometry (expressed by the 2nd fundamental form of leaves) and its relations with mixed curvature, topology and dynamics of foliations on compact (or of finite volume) manifolds.      The research objectives are to go deeply in studying foliations using the methods of Riemannian geometry, theory of submanifolds, topology and dynamics, computer simulations. Among the (hoped for) results are new integral formulae for foliations on Riemannian manifolds, connectedness properties of (k, ε)-saddle (saddle, totally geodesic) foliations, and applications of them to the following problems:    – Walczak problem: to recover a metric on a foliated manifold by higher mean curvatures of a foliation or its orthogonal distribution;    – Gluck-Ziller problem: minimizing certain functions like volume and energy defined for plane fields on Riemannian manifolds, considered as maps into the (co)tangent Grassmann bundles equipped with Cheeger-Gromoll type metrics;    – Toponogov problem: to generalize Ferus’s theorem for the case of foliations with non-negative (positive) mixed curvature.  The topic belongs to differential geometry and topology, subjects of pure mathematics.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'A code of practice for the dosimetry of boron neutron capture therapy (BNCT) in Europe'.

assistant: **Concept**

The objective of the proposal is to prepare detailed guidelines for the dosimetry of epithermal neutrons to be used for the treatment of cancer patients by boron neutron capture therapy (BNCT), currently in advanced state of development at many European research reactors and accelerators. BNCT is a new form of radiotherapy which is expected, on solid grounds, to present major benefits in the treatment of very severe forms of cancer, as for instance braintumours of the type glioma. For the dosimetric measurements, whether in pre-clinical research or in clinical trials on human patients, these guidelines will ensure the level of accuracy, reliability and reproducibility, which is generally required in radiotherapy and which will be of crucial importance for the success and optimization of the BNCT treatments. The final outcome of the project will be a published code of practice for use by all European BNCT centres. In order to meet the objectives the work is divided into four work packages, in which the basic characteristics of the neutron beam (beam geometry, neutron and photon spectra, absorbed dose and fluence distributions) will be determined in a coherent and reproducible way. The scientific justification of the project is the necessity to ensure the comparability and critical appraisal of the results from various pre-clinical radiobiological experiments as well as the clinical trials on human patients. It is essential and feasible to introduce European uniformity of BNCT dosimetryat the present state of development of BNCT in Europe.The existing international recommendations on radiotherapy dosimetry are not applicable to BNCT due to the complexity of the mixed neutron- and gamma-fields. Hence, guidance on acceptable dosimetric procedures on a European level is urge
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Development of high durability and performance concrete by using pozzolans and optimum material synthesis'.

assistant: **Innovation**

The objective of the proposed project is the investigation, the industrial production and the reliability control of an improved concrete type of high durability, as well as of high performance to all other conventional requirements (HDPC). This product arises by using artificial or natural pozzolans, simultaneously with rational design of relating proportions of its rest constituents (cement, aggregates, water, additives), as preliminary investigations by Papadakis et al., and DTI have shown. The most important aims of the project are: Theoretical and experimental investigation of the pozzolanic activity and its effects on the properties of fresh and hardened concrete, development of HDPC, formulation of use specifications, transfer to the construction reality and performance control. The project will be carried out at the DTI- Division of Building Technology; the Denmark's largest organization on concrete technology research, from Dr. V. G. Papadakis, who has developed part of the-basic research, in cooperation with the well specialized on concrete optimization subjects, local research team.