RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Technology and hardware for neuromorphic computing' (TEMPO) targeting Horizon 2020.

assistant: **Abstract**

Massive adoption of computing in all aspects of human activity has led to unprecedented growth in the amount of data generated. Machine learning has been employed to classify and infer patterns from this abundance of raw data, at various levels of abstraction. Among the algorithms used, brain-inspired, or “neuromorphic”, computation provides a wide range of classification and/or prediction tools. Additionally, certain implementations come about with a significant promise of energy efficiency: highly optimized Deep Neural Network (DNN) engines, ranging up to the efficiency promise of exploratory Spiking Neural Networks (SNN). Given the slowdown of silicon-only scaling, it is important to extend the roadmap of neuromorphic implementations by leveraging fitting technology innovations. Along these lines, the current project aims to sweep technology options, covering emerging memories and 3D integration, and attempt to pair them with contemporary (DNN) and exploratory (SNN) neuromorphic computing paradigms. The process- and design-compatibility of each technology option will be assessed with respect to established integration practices. Core computational kernels of such DNN/SNN algorithms (e.g. dot-product/integrate-and-fire engines) will be reduced to practice in representative demonstrators.


**Keywords:** Application-Specific Integrated Circuit (ASIC),  Classification,  Deep Neural Networks,  Interference,  MRAM,  Non-Volatile Memory,  OxRAM,  Spiking Neural Networks
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Pinpoint-NMR: A sequence-specific labeling technique to accelerate NMR investigation of large proteins' under Horizon Europe.

assistant: **Concept**

The cell is an ensemble of dynamic molecular machines. NMR spectroscopy is the method of choice to observe complex conformational changes, transient interactions, and dynamics of proteins at atomic resolution. The introduction of methyl-specific labeling has made it possible to study protein assemblies of several hundred kDa by solution NMR. However, the high number of overlapping signals and the labor-intensive process of site specific analysis hamper NMR investigation of large hetero-oligomeric assemblies at room temperature. While segmental labeling or site-specific labeling offer opportunities to simplify 2D NMR spectra, the complexity of sample preparation or the characteristic low expression yield drastically limit its subsequent applications. Therefore, efficient, widely applicable, and straightforward labeling strategies are necessary to integrate solution NMR analysis of large proteins (such as monoclonal antibodies) into R&D pipelines for biomedical industry. I propose to harness the natural (anti)codon code for multi-site, sequence-specific isotope labeling. The resulting method would simplify the spectral congestion typical of 2D NMR spectra of large proteins, allowing targeted investigation of sites of interest (e.g. catalytic centers) and streamlining residue assignment. This method will reduce the time required for residue specific analysis of NMR data from months to days, thus expanding our ability to study large, medically-relevant complexes and address current biological challenges.


**Keywords:** Protein, NMR, nuclear magnetic resonance, isotopic labeling, methyl, cell-free, tRNA, assignment
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Abstract semantic frameworks for implicit complexity' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Implicit computational complexity studies theory and applications of machine-independent approaches to computational complexity, with particular emphasis on approaches based on mathematical logic. Although related one to the other, all the proposed systems have been studied with different, often unrelated methodologies, and few results are known about relative intentional expressive power. For example, it is not clear at all whether combining different systems into one language would break the correspondence to complexity classes. Similarly, it is not usually the case that a system can be extended with new features preserving its quantitative properties. What is needed, are some unifying semantic frameworks for the analysis of resource consumptions of programming languages and proof systems. Such frameworks should be powerful enough to capture a wide amount of systems and programming language, but simple enough to be useful in studying quantitative properties of programs and proofs.Abstract semantic framework s for implicit computational complexity will be investigated. Particular emphasis will be placed on approaches based on game semantics, geometry of interaction and coherence semantics. The major expected result is the definition of an abstract mathematical structure in which heterogeneous systems inside implicit computational complexity can be interpreted. Crucially, the model must be sufficiently rich to reflect the quantitative behaviour of the interpreted object, in contrast to usual denotational semantics. The investigation will proceed in two steps. First of all, game models and geometry of interaction models will be developed in such a way that a large class of subsystems of linear logic (including the so called light logics) can be interpreted, studied and c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Decision Support on Security Investment' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The DESSI project will develop a highly structured and versatile method for Decision Support on Security Investment, which provides a participatory assessment process, which takes into account the many and complex societal dimensions of security investment decisions.The method will be developed through a combination of foresight and technology assessment methodologies, threat, security and criminology research, and praxis in multi-criteria assessment methods in fields such as cost-benefit analysis, risk assessment and impact assessment. The user will be able to compare alternative ways of counteracting a specific threat. The comparison will be made on a set of dimensions in security investment decisions, such as security gain, privacy impact, social implications, political significance, and economy. The assessment will be future-oriented by testing the investments against a set of future scenarios on possible changes in the societal context, thereby checking the robustness of decisions. DESSI will include participatory procedures, in which users, stakeholders, experts, decision-makers and/or citizens contribute to the structured consultation process, and thereby ensuring a balanced and broadly accepted assessment. It includes an internet-based work-flow tool.The method provides for overview and insight into the pros and cons of a certain investment, as compared to a set of alternatives, and leave the final decision up to the user. A strong dissemination strategy ensures effective diffusion of the method.The DESSI consortium contains expertise in: High-level decision support and advice; Conflict and national security research; Criminology and inner security; Impact assessment procedures; Foresight praxis; Participatory methodologies; Cost-benefit analysis and innovation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Innovative numerical methods for non-Newtonian flows and porous media' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The InNoPor project focuses on developing and analyzing innovative numerical methods to solve complex problems in engineering and science involving non-Newtonian flows and porous media. The project will address realistic applications such as volcanology and chromatographic filtering. The network includes eight universities and research centers from Spain, the UK, Germany, and Chile, fostering long-term collaboration. Advanced modeling of non-Newtonian flows in porous media plays a crucial role in soil remediation, water purification, and the development of sustainable technologies for agriculture, energy, and environmental management. InNoPor aligns with several UN Sustainable Development Goals (6, 7, 9, and 13) and aims to contribute to European sustainability and technological innovation priorities. The project seeks to create impactful solutions for academia and industry by leveraging cutting-edge numerical techniques and interdisciplinary collaboration.


**Keywords:** Applications of Mathematics in Science,  Porous media,  Geophysics,  Inverse problems
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Multifunctional facades of reduced thickness for fast and cost-effective retrofitting' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The project aims to deal with the numerous requirements of facade panel retrofitting by developing a light-weight, durable, cost effective and high performance panel. Its layered structure allows for separate but also synergistic function regarding high thermal and acoustic insulation, excellent mechanical properties, up to standards flame retardancy and photocatalytic activity. Employing nanofillers such as CNTs, TiO2 and perlite nanoparticles and cellular nanofibers, will lead to reduction of facade panel weight and thickness by at least 40%. Furthermore, individual components have a definite environmental orientation, taking advantage of recycled materials and biomass foams, low energy and low toxicity processes. Finally, project viability and sustainability will be ensured by performing a Life Cycle Analysis in order to optimize individual processes. Hygrothermal behaviour and thermodynamics will also be simulated and modelled to ensure the high performance of the panel.The project’s advancements will be1. Customization possibilities: Apart from panel thickness which can be easily tuned, integrated encapsulated nano-PCMs will be tailored along the customer needs regarding temperature of phase change.2. Easy and fast to install: It is calculated that 10m2 can be installed in less than 3 hours by 2 workers3. High acoustic and thermal insulation: The three internal layers offer varying degrees of insulation, with an ultra-light aerogel middle layer boasting thermal coefficients lower than 0.012 W/mK, thus allowing insulating layers 3 to 4 times thinner than conventional ones.4. Photocatalytic activity offering self cleaning and antimicrobial behaviour, virtue of the surface coating. In addition, the surface coating will also contribute to flame retardancy due to nanofi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Real-time optimal control of wind-farm atmosphere interaction' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Current Wind-Farm flow Control (WFC) focuses on the interaction of wind turbines through their wakes, and relies on fast heuristic wake models that are mostly considered in an open-loop control framework. However, modern wind farms interact with the atmosphere at much larger scales, such, e.g., as their excitation of atmospheric gravity waves. WFC response is thereby not only governed by intra-farm turbine wakes, but possibly even more by the interaction between the larger atmospheric mesoscales and the farm operation. The only models that realistically capture these aspects down to the wake scale are large-eddy simulations (LES), which are generally run on high-performance computers, yet considered orders of magnitude too slow for use in real-time model predictive control.Recently however, we have shown that coarse-grid LES integrated in a time-decoupled model predictive control (TDMPC) framework, is about a factor three too slow only for real-time use, while potentially still being effective at realizing the WFC objective. With wind turbines being the largest manmade “flow actuators” existing today, and smaller-sized systems exhibiting faster time scales, the wind farm will be the first turbulent flow system in which LES can be used as a real-time control model.We aim at inducing a paradigm shift in the use of LES, by developing a first fully integrated LES-based TDMPC and demonstrate it in a high-fidelity emulator environment, as well as, in part, using field data. This raises following fundamental research challenges: diverging sensitivities of perturbations in turbulent flows (chaotic systems) over long time horizons, the sparse nature of measurements in the atmosphere required for state estimation in the control loop, the limited understanding of wind-farm atmosph
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Structure based design and development of inhibitors of the protein tyrosine phosphatase and its role towards the insulin receptor kinase' (1994-1998).

assistant: **Concept**

Protein Tyrosine Phosphatases (PTPs) are enzymes that remove phosphate from tyrosine residues of cellular proteins. They are believed to play an active role in such diverse pathological events as diabetes, cancer and immune deficiency. Rational design of inhibitors which can act with a high specificity and selectivity towards certain PTPs will be the aim of our project which will be carried out at Dr. S. Toxvaerd's laboratory in close collaboration with Novo Nordisk's computational group. Drug design computational techniques such as LUDI, HOOK, Leapfrog, etc. will be used to generate the drug candidates. Ligand /protein affinity will be evaluated using different computational techniques. Molecular dynamics simulations will provide relevant information on the binding affinity and selectivity of the designed inhibitors. Ab initio methods will be used to parametrize the force fields used in the system minimizations and dynamics simulations.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Ultimate Paleo-Ocean Records from Biogenic Calcites' to be submitted under Horizon 2020.

assistant: **Abstract**

The ambition with this proposal is to create ultimate paleo-environmental records for the oceans. This is a fundamental scientific challenge and the motivation is simple: The oceans take up 70% of the Earth’s surface area and represent an immense sink/source of, e.g., heat and CO2, which makes them key to the evolution of Earth’s climate. Assessing and understanding anthropogenic global climate change requires that role of the oceans is understood in detail. Proxies are needed to establish past ocean conditions with high accuracy.    Calcite has played a fundamental role in these efforts because isotopic and trace element compositions of limestone and calcitic fossils are related to ocean conditions at the time of their formation. Geochemical studies of calcite in the ocean sediment record have therefore contributed enormously to the understanding of Earth’s climatic evolution over the last several hundred million years.     However, our recent work (Bernard et al., Nature Communications, 2017) identifies a fundamental problem: Visually imperceptible, ultrastructure-level processes that occur during sediment diagenesis can introduce a very strong bias in these records, in particular those based on biogenic calcite; i.e., structures produced by living organisms such as foraminifera and brachiopods. Previously not investigated or taken into account, such ultrastructure-level diagenesis will (and does) create large errors in ocean paleo-environmental reconstructions, even under the close-to-ambient pressure and temperature conditions characterizing shallow sediment burial. This proposal offers a solution: An entirely new, interdisciplinary approach, including ultra-high-resolution isotopic imaging (NanoSIMS), is developed here to quantify these effects in a broad range of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Innovative diagnostic and eHealth monitoring system for diabetic foot complications' (FeetWell), addressing dissemination and exploitation.

assistant: **Impact**

In 2014 422 million adults in the world suffered from diabetes, and the increasingly sedentary ways of life will contribute to the “growth” of this disease. Diabetic foot ulcers (DFUs) are one of the most common complications of diabetes, accounting for most of diabetic patients’ hospitalization, and being the direct cause for 50% of all non-traumatic amputations. This also implies substantial healthcare costs: compared with “healthy” diabetic patients, the cost of care for patients with a foot ulcer is 5.4 times higher, and across the EU, ulcer complications’ care adds 7- 10 € billion to direct yearly costs. Early diagnosis can have a significant impact on decreasing the impact of DFUs. However, this is not a simple task, as current methods for the diagnosis of DFUs rely only on foot inspection by doctors and decades-old microbiological techniques. Therefore, there is an urgent need for technologies that enable early diagnosis of DFUs so as to minimise their consequences. FeetWell™ is the response to this need: a user-friendly device based on the merging of different monitoring technologies (IR Thermography, Ultrasonography and Dermatoscopy) to facilitate early detection of microvascular and macrovascular foot complications. Moreover, as it is a simple to use device, it will empower patients, making them less reliant on doctor visits and increasing their engagement into their self-care. Feetwell is a strategic project for our company, Metis Baltic, as it will enable us to bridge the gap between previous R&D projects and launch ourselves into the medical diagnostic tools’ market as the developers of the 1st automated diabetic foot inspection device on the market, by 2020 reaching revenues of €16.5 million by 2022, with a ROI of 2.2, and multiplying by 10 our staff. But
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Novel device for simple and effective prevention of post-surgical adhesion build up.' in the context of a Horizon 2020 call.

assistant: **Objectives**

Surgical adhesions are a consequence of abdominal trauma during surgery. Although there are a multitude of available barriers on the market today, the efficacy of these solutions is still in question and can lead to adverse side effects. If untreated, these surgical adhesions can solidify and grow, potentially leading to infertility, chronic pain, and difficulties in repeat operations. To address adhesions, patients must undergo additional abdominal surgery, putting unnecessary stress on existing healthcare systems. On average, 35% of patients who undergo  open abdominal or pelvic surgery are readmitted twice in the following 10 years  due to complications. EIO Biomedical has developed a revolutionary anti-adhesion system in order to eliminate initial formation of surgical adhesions. The FuseX system, delivers a mixture of donor blood plasma with a concentrated mix of natural coagulation factors found in the blood. This results in  less post-surgical adhesions, and related complications, and translates to an estimated 6-12 B€ in saved expenses per year. Preliminary testing of the material demonstrated a 60-90% reduction of adhesions, depending on the severity, whilst the non-invasive laparoscopic application also reduced open wound size and extent of trauma. During the phase 1 project, a go-to-market strategy and a supply chain will be established, as well as further development plan will be drafted. Within the overall innovation project, EIO Biomedical is set to initiate safety and efficiency trials in Lithuania and Spain, where they will initially market their product. After initial testing,  device function and efficiency will be further improved to enable a more rapid procedure for scale up to commercialization. Post-commercialization, CEO Dr. Yair Pilpel hopes to i