RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'A new standard for integrating polygraphic sleep recordings into a comprehensive model of human sleep and its validation in sleep disorders' to be submitted under Fourth Framework.

assistant: **Abstract**

- To develop an enhanced computer-based system for analyzing polysomnographies, which is reliable, reproducible, does not rely on rules to be interpreted by humans, describes sleep on a smaller temporal resolution and goes beyond the classical discrete status.- To obtain an increased understanding of the contribution of particular variables to sleep analysis, which previously have not been considered extensively for sleep scoring.- To arrive at an improved description of sleep for subjects which do not fall into the categories of R&K - e.g. elderly persons, sleep disturbed patients, and so on.This project aims at extensive novel research on the architecture of nocturnal human sleep, as well as the development and evaluation of advanced methods for sleep analysis, based on polygraphic measurements, most prominently electroencephalography (EEG). The main need for a novel standard of modelling sleep comes from the limits of the only widely accepted standard -- a sleep manual according to Rechtschaffen & Kales -- and the increasing dissatisfaction with it among clinicians.SIESTA aims at a computerized system for analyzing sleep that:- has a higher temporal resolution - describes major parts of sleep as a continuum - does not depend on subjective rules - incorporates a great variety of biosignals - is validated on a large corpus of data (normals + patients with sleep disturbances)Sleep analysis is of vital importance for the diagnosis and treatment of various kinds of sleep disturbances and psychiatric or neurological disorders. Chronic disturbed sleep has a decisive influence on health. If sleep is not able to fulfil its functions of alleviating tiredness, this can influence behavior and mood during the day, causing inefficiency at work, absenteeism, or even accidents. Furt
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Functional analysis of orphan cytochrome P450 genes in A. thaliana: P450s and flower development'.

assistant: **Concept**

Reproduction is one of the most important events in an organism. In crops, it governs seed yields, viability and organoleptic properties. The regulation of reproduction happens in plants at the flowering stage.Thus understanding of the whole process, including as initiation, signalling, growth and induction of second metabolites biosynthesis during flower development is necessary to clarify the mechanism of plant reproduction. Cytochrome P450 (P450) is one of the largest enzyme families in higher plant. P 450s are involved in the biosynthesis of various secondary metabolites related to defence responses or developmental events, as key monooxygenases.In my host institution, a global P450 transcriptome analysis demonstrated that more than 120 P450 genes are expressed during flower development in Arabidopsis thaliana. Among them, five genes are expressed in the tapetum during the early stages of the pollen development. Three of these genes are activated upon insect attack. Thus their products might be involved in signalling and regulation of pollen development, or synthesis of physical barriers in higher plant.My goal is to figure out 1) what is their biochemical substrate, and 2) what is the biological role of their products in plant development and defence. This will be achieved using existing silenced and over-expressing mutants of the genes of interest for metabolic profiling, analysis of the pollen structure and biology (viability, germination), and testing for insect resistance.Completely successful work shouldestablish a correlation between P450 expression, metabolic activity, pollen composition and properties, and variable defence response. It should therefore help understanding co-evolution of development and defence.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Empowering the Service Economy with SLA-aware Infrastructures' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The ongoing transformation of a product-oriented economy towards a service-oriented economy has come to a critical point. IT-supported service provisioning is of major relevance in all industries and domains. However, the nature of these setups is typically quite static because it requires significant effort to create service offers, to negotiate provisioning details with customers and to manage and control provided services.<br/>The research project SLA@SOI will provide a major milestone for the further evolution towards a service-oriented economy, where IT-based services can be flexibly traded as economic good, i.e. under well defined and dependable conditions and with clearly associated costs. Eventually, this will allow for dynamic value networks that can be flexibly instantiated thus driving innovation and competitiveness<br/>The technical approach of SLA@SOI is to define a holistic view for the management of service level agreements (SLAs) and to implement an SLA management framework that can be easily integrated into a service-oriented infrastructure (SOI). The main innovative features of the project are (1) an automated e-contracting framework, (2) systematic grounding of SLAs from the business level down to the infrastructure, (3) exploitation of virtualization technologies at infrastructure level for SLA enforcement, and (4) advanced engineering methodologies for creation of predictable and manageable services.<br/>SLA@SOI will provide its results in 2 complementing ways. First, an open source based SLA management framework will allow for realizing the benefits of predictability, transparency and automation in an arbitrary service-oriented infrastructure. Second, in-depth guidance for industrial stakeholders will be given explaining the best practise on how to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Blue-Cloud: Piloting innovative services for Marine Research & the Blue Economy' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Blue-Cloud addresses the IA ‘The Future of Seas and Oceans Flagship Initiative’ (BG-07-2019-2020) for the following topic: [A] 2019 - Blue Cloud services. The project implements a practical approach to address the potential of cloud based open science to achieve a set of services identifying also longer term challenges to build and demonstrate the Pilot Blue Cloud as a thematic EOSC cloud to support research to better understand & manage the many aspects of ocean sustainability, through a set of five pilot Blue-Cloud demonstrators. It seeks to capitalise on what exists already and to develop and deploy, through a pragmatic workplan, the pilot Blue Cloud as a cyber platform bringing together and providing access to: 1) multidisciplinary data from observations and models, 2) analytical tools, & 3) computing facilities essential for key blue science use cases. Outputs include: a Blue Cloud Framework, Data Discovery & Access Service (approx. 400 users) & VRE (approx. 1,000 users) from 25 countries, Blue Cloud Service Catalogue including 50+ services deployed through 5 compelling pilot demonstrators, A Blue Cloud 2030 implementation Policy Roadmap, Whitepaper on outcomes of the Food/Blue-Cloud Pilots to support the implementation of thematic EOSC, 4 focused Roadmap events & Workshops, 1 hackathon, 10 webinars, 1 Final results conference, engaged community with all stakeholder groups represented. Led by a consortium bringing together leading European marine data management infrastructures, EOSC horizontal e-infrastructures, and excellent marine researchers. Coordinated by a neutral ICT intensive SME with over 15 years’ experience, technically coordinated by a community leading marine & ocean data specialist, and supported by 17 experienced partners, from research, academia &
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Social protection in europe. convergence? integration, accession and the free movement of labour.'.

assistant: **Concept**

This Thematic Network is about providing access to existing data in the EU and the Accession Countries (AC) that is necessary to qualify and quantify the impact of enlargement on the free movement of labour in all its social aspects (Health, Pensions and Unemployment, HPU). We will go further to include monitoring information on the status of social protection reform in the AC, including their introducing of the acquis communautaire. We carry out specific research activities, using our data and information to forecast future developments in HPU that have a major impact on socio-economic development and on policy making in the EU. We want to know and work on the question to what extent Europeanisation leads to a further convergence of the different social protection systems in the MS and the AC?
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Anthropogenic Aerosols Triggering and Invigorating Severe Storms', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

Recent studies of cloud interactions with particulate air pollution, performed mostly on a conceptual level, show that pollution aerosols can invigorate convection into severe storms. The convective storms are defined as severe when they produce at least one of the following phenomena: strong local winds, downbursts, frequent lightning, large hail and tornados. The pollution aerosols can slow the conversion of cloud drops into precipitation, allowing the convective energy to accumulate and eventually tri gger violent storms. The new METEOSAT Second Generation (MSG) geostationary satellite, commissioned in January 2004 by the European Organization for the Exploitation of Meteorological Satellites (EUMETSAT), can significantly help identifying in real tim e the impacts of pollution aerosols on cloud structure, and thus potentially provide advanced warning of such events. We propose to use the satellite and ground based observations in conjunction with computer models to distinguish the meteorological and pollution aerosols effects on triggering and invigorating severe convective storms, and hence causing man-made natural disasters". Such events and their mitigation are not covered by FP6. In addition to fundamental understanding of the anthropogenic role in influencing severe storms, the project will provide the scientific basis to improve the skill of numerical weather prediction (NWP) models to predict such storms. The ultimate challenge may be to develop a method by which severe storm development can b e mitigated, for example by reducing aerosol pollution, or even reverse the effect of the small pollution aerosols by introducing large hygroscopic aerosols that accelerate the early onset of rain. The scientific basis of such a possibility will be evalua ted."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Evaluating Aerobic Microbial Methane Cycling under Archaean-Proterozoic Environmental Conditions' in the context of a Seventh Framework call.

assistant: **Objectives**

Earth’s surficial chemistry evolved in close association with life, exemplified by the incorporation of trace metals into the active sites of many enzymes involved in major biogeochemical processes and as structural components of proteins. Consequently, trace metal bioavailability has likely exerted a major influence upon rates of specific microbial processes throughout Earth history. Changes in the bioavailability of trace metals would have had a significant impact on microbial processes and biogeochemical elemental cycling across Earth’s first Great Oxidation Event (GOE) ca. 2.3 billion years ago (Ga), when atmospheric O2 rose from essentially nothing to ca. 1-5% of present atmospheric levels (PAL). At this time, ocean chemistry evolved from anoxic and Fe-rich to the widespread occurrence of deeper water sulphidic conditions. During this early oxygenation period, dominant microbial pathways would have shifted considerably. For example, microaerophilic CH4 oxidation predicted to have evolved by 2.7 Ga, may have become more important as surface waters became oxygenated, and could have reduced CH4 emissions into the Precambrian atmosphere by up to 90%. This could have potentially contributed to the development of widespread glaciations by 2.3 Ga, and to the depletion of a significant sink for O2, thereby facilitating the rise of atmospheric O2. However, rates of microbial activity and the interaction of various key microorganisms under the chemical conditions existing at that time remain poorly constrained. In this proposal, microbial experiments will be combined with Cu (regulates the synthesis, expression and activity of CH4 monooxygenases)  isotopic analyses of key late Archaean to mid-Proterozoic geologic successions, to test hypotheses pertinent to aerobic biologica
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Harmonic Analysis and l-adic sheaves' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

In  recent years there has been impressive development of the higher category theory and in particular development of the categorical counterpart of the Langlands conjecture over fields of finite characteristic. But until now, this development has had little bearing on the classical problems which deal with spaces of functions. The main goal of this proposal is to build the technique to apply the category theory  to classical problems. Of course on the way I will have to deal with problems in the categorical realm.The first part of the proposal deals with construction of characters of irreducible representations of reductive groups over local nonarchimedian fields F in terms of traces of the Frobenious endomorphisms which should lead to the proof of the ""Stable center conjecture"" at least for representations of depth zero.The second part is on the extension of the definition of L-functions of representations of reductive F-groups  corresponding to an arbitrary representation of the dual groups. As it is now, the definition is known only for very special representations of the dual group and only in the case of classical groups.The third part is on the extension of the classical theory to representations of Kac-Moody groups over local fields.""


**Keywords:** Representation theory, Infinity categories, l-adic sheaves
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Lab-on-chip based protein profiling for Cancer diagnosis', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

The human plasma proteome holds the promise of a revolution in disease diagnosis and therapy. One major breakthrough should come from the detection of multiprotein disease markers including isoforms. We propose to integrate a full proteomics analysis chain, from blood sample to the diagnosis information, combining bio-, nano, and information-related technologies. It includes an innovative patented lab-on-chip developed at CEA. The clinical application is early pancreatic cancer diagnosis.The project is based on a panel of 3 identified proteins, a protein isolation protocol, an optimised chromatographic-electrospray lab-on-chip, an Integrated Clinico-Proteomics Environment including a Proteomic Information Management System, a Clinical Information System, and modules for preprocessing, reconstruction, visualisation, protein identification, data mining and knowledge discovery. The clinical validation is applied to a cohort of 92 patients. Our targeted performance is to get at least the sensitivity of an orthogonal ELISA approach, to operate the analysis chain in less than 12 hours, and to demonstrate the interest of multiprotein marker.The main research outcomes will be an optimised chromatographic-electrospray lab-on-chip, a software environment supporting the integrated device, a proof-of-concept of their application to protein profiling for cancer diagnosis and an exploitation plan. The roadmap of this 36 months project is defined according to three main milestones: 1) at month 12, a first protein profile using a first version of the lab-on-chip on artificial samples is available, 2) at month 24, all the final versions of the sub-systems are ready for integration and validation, 3) at month 33, the validation on clinical samples is completed.The consortium partnership
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Treble-CLEF: Evaluation, Best Practices and Collaboration for Multilingual Information Access' (Treble-CLEF) under Seventh Framework.

assistant: **Objectives**

The popularity of Internet and the consequent global availability of networked information sources and digital libraries has led to a strong demand for multilingual access and communication technologies. Such technologies should support the timely and cost-effective provision of knowledge-intensive services for all members of linguistically and culturally diverse communities. This is particularly true in the multilingual setting of Europe. However, despite recent research advances, there are still very few operational systems in existence, and these are limited to the most widely used languages. The challenge that must now be faced is how to best transfer the research results to the wider market place. The objective of the Treble-CLEF proposal is to build on and extend the results already achieved by the existing Cross Language Evaluation Forum. The aim is not only  to support the development and consolidation of expertise in the multidisciplinary research area of multilingual information access but also to disseminate this knowhow to the application communities. The specific target would be the European digital library context. Treble-CLEF would thus:<br/><br/>- support the annual CLEF system evaluation campaigns with tracks designed to meet the specific requirements of the user and application communities, and particular focus on user modeling, language-specific experimentation, and results presentation<br/><br/>- launch a concerted action of technology transfer and dissemination of knowhow, tools, resources and best practice guidelines through the organisation of workshops,  tutorials and training sessions <br/><br/>- encourage community-building and collaboration around this topic by providing a forum for the discussion of results and making the scientific data, exp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The Human Behavioral Immune System: Consequences for Health and Innovation' under Horizon 2020.

assistant: **Concept**

Modern innovations such as soap, condoms, and indoor plumbing have allowed billions of people to reduce their contact with viruses and bacteria and, as a result, dramatically increase length and quality of life. But how did members of the genus homo avoid pathogens for the two million years that preceded these technological innovations and, more broadly, discoveries that infectious disease is caused by microbes? And, importantly, how do any natural behavioral defenses against pathogens impact our behavior in the modern world? Recent research and theory in the field of evolutionary psychology suggests that natural selection has shaped a human behavioral immune system (HBIS)—a suite of psychological mechanisms, ranging from aspects of our olfactory systems (e.g., that detect specific chemical compounds) to our emotion systems (e.g., the emotion disgust) and our learning systems (e.g., conditioned aversions to foods) that are coordinated for a common function: to detect and motivate the avoidance of pathogens. Given that myriad universal human behaviors connote some pathogen risk—including interpersonal contact, mating, and eating—gaining a holistic understanding of the HBIS has the potential to offer critical new insights into multiple fundamental aspects of human nature. Here, I utilize an interdisciplinary approach to answer three foundational, yet currently opaque questions concerning the nature of the HBIS, including: (1) Where does trait variation in HBIS activation come from? (2) What effect does the HBIS have on behavior when cues to pathogens are detected? and (3) How does the HBIS facilitate learning of avoidance and rejection? To answer these questions, I propose an array of methodologically diverse studies to investigate how trait HBIS activation shapes rejecti