RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'An Integrated Platform for Developing Brain Cancer Diagnostic Techniques', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The mission of AiPBAND is to train a new generation of entrepreneurial and innovative early-stage researchers (ESRs) in the early diagnosis of brain tumours using molecular biomarkers in the blood, meeting the medical and societal challenges of this emerging field. AiPBAND will focus on gliomas, a range of devastating and progressive brain tumours affecting around 25,000 people each year in Europe and responsible for the majority of deaths from primary brain tumours.Fourteen fellows will be trained by experts in 9 academic and 3 non-academic beneficiaries, belonging to 5 EU member states and 6 partner organizations (4 private sectors and 2 international academic), with fields ranging from neuroscience, engineering (including big data science), healthcare to economics. State-of-the-art technologies will be applied in parallel to (i) identify novel blood biomarkers from patients with gliomas, (ii) design three types of multiplex biosensor (plasmonic-based, graphene-based, and digital ELISA assay-based), (iii) develop a big data-empowered intelligent data management infrastructure, and (iv) develop cloud-based diagnostic systems. Proof-of-concept will be evaluated through clinical trials to assess accuracy, sensitivity and specificity. The elaborately designed individual research projects under the Vitae Researcher Development Framework – carefully arranged into local training courses, network wide events, secondments, personalized career development plans, with strong involvement of the private sector – will ensure exploitation of AiPBAND's achievements, and will maximize the ESRs’ abilities in creative & innovative thinking, triple-i knowledge transformation, and encourage a business-orientated mind-set and entrepreneurship.


**Keywords:** Cancer, Biosensing Techniques,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Next generation of information systems to support EU external policies'.

assistant: **Objectives**

The 2016 European Union Global Strategy for Foreign and Security Policy (EUGS) highlights the need to enhance external policies by pursuing better communication, information-sharing, joint reporting, analysis and response planning between member state embassies, EU delegations, Commission services, EU Special Representatives and Common Security and Defence Policy (CSDP) missions. The CIVILnEXt project supports the development of a solution addressing existing “fragmentation” and closing “gaps”. To provide civilian CSDP missions with the next generation of secure and cost-effective information systems: a situational awareness, information exchange and operation control platform (OCP). Fully informed of contributing initiatives in civilian CSDP and EU external action, the project will aim to develop solutions leveraging on the results extracted from projects funded by the EU. The common challenge in CIVILnEXt is to develop, test and validate a cost-effective and interoperable operation control platform (OCP) that will support the conduct of civilian CSDP missions. The OCP will improve coordination in EU external action through better information exchange, situational awareness and operation control in diverse theaters of operation. It will support the EU’s comprehensive approach in complex missions, including the civil-military cooperation within CSDP, facilitate the engagement CSDP actors, creating links EU Delegations, FRONTEX, ECHO and other EU activities, member states, as appropriate, and other partners such as the UN and regional organisations. CIVILnEXt engages the participation of four national competent authorities, active in EU external policies and the UN organisations IOM.  They share the need to become beneficiaries of procurement results that enhance the eff
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Ice-ocean interactions during Heinrich Events in the Labrador Sea' (IceLab) targeting Horizon 2020.

assistant: **Abstract**

Northern hemisphere ice sheets are particularly vulnerable to climate change as the Arctic is warming twice as fast as the rest of the planet. Scenarios of future ice sheet stability, however, are associated with significant uncertainty, due to a lack of understanding of the relevant internal climate feedbacks. These processes involve ocean-ice sheet interactions and the effects of sea ice on the terrestrial cryosphere. With increased societal concerns over rising sea levels, it is more than ever important to understand the implications of climate change for ice sheet stability. The key lies in understanding the response of past ice sheets to climate change. Prominent episodes of past ice-sheet collapse are so-called Heinrich events during the last glacial period, originating in Hudson Strait. While modelling studies have long hinted at the importance of sea ice in the Labrador Sea for subsurface warming and ocean induced melting during Heinrich events, this has not been shown using proxy methods. My project will investigate the links and feedbacks of sea ice, ocean circulation, subsurface warming, and ice-sheet collapse in the Labrador Sea to determine the role of the coupled cryosphere-ocean system for ice sheet stability across. Additionally, the effect of enhanced freshwater discharge on the system will be documented and a spatial-temporal map of North Atlantic sea ice dynamics across Heinrich events will be constructed. I will apply an integrated approach of organic and inorganic geochemistry, using sea-ice biomarkers, foraminiferal isotopes, and foraminiferal trace metals (i.e. Mg/Ca) in combination with state-of-the-art dating and correlation techniques. The new records will provide important clues with respect to a potential oceanic trigger of Hudson Strait iceb
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The chemical exposoMe of pregnAnt womeN with GestatiOnal diabetes mellitus' (MANGO) under Horizon Europe.

assistant: **Objectives**

There is a lack of knowledge on the multitude of chemicals that we are exposed to, and even less is known about the exposure during pregnancy, the most critical window for adverse health effects on both mother and offspring.  In turn, the prevalence of Gestational Diabetes Mellitus (GDM) has incredibly increased during the last decades and it is now diagnosed in up to 18% of the pregnancies. In this context, I propose the project “The Chemical Exposome of Pregnant Women with Gestational Diabetes Mellitus (MANGO)” to be co-supervised by Dr. Navas-Acien and Prof. Gary Miller at Columbia Mailman School of Public Health (USA, Third Country for the outgoing phase), and by Prof. Domingo at Universitat Rovira i Virgili (URV, Spain, beneficiary institution and host for the incoming phase). The main scientific goals of MANGO are: (1) to determine the occurrence of non-target chemicals in biological samples of 400 pregnant women; (2) to evaluate the association between the exposure to chemicals and clinical data, exploring the effect modification by sociodemographic, dietary and lifestyle factors; (3) to implement a pilot prevention programme to minimize the exposure to hazardous chemicals during pregnancy. These objectives will be tackled by integrating last advances in high-resolution mass spectrometry (WP1), mathematical models (WP2) and risk assessment and prevention strategies (WP3). MANGO will leverage biological samples of Diabetes and Pregnancy Cohort from Institut d’Investigació Sanitària Pere Virgili/Hospital Universitari Joan XXIII (IISPV/HJXXIII, associated partner) and will return the knowledge to Europe by implementing the first pilot programme to increase the awareness of the exposure to hazardous chemicals. Through this MSCA-PF-GF, my training in environmental epi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Employing quantitative high-resolution imaging to understand mechanistic principles of ESCRT-mediated membrane fission in dividing cells' (2007-2013) targeting Seventh Framework.

assistant: **Abstract**

The ESCRT machinery is a multi-protein complex involved in membrane constriction and fission in a variety of processes in cells including receptor degradation, viral budding and cytokinesis. The mechanism by which ESCRT proteins drive membrane fission in cells is still largely unknown. Using super resolution fluorescence microscopy and quantitative live cells imaging I have recently mapped the spatiotemporal organization of ESCRTs in cytokinesis. The results identified a sequential recruitment of ESCRT proteins into a series of partially overlapping cortical ring structures and indicated the ESCRT machinery as the driving force for the membrane cleavage event required for cell separation. This work highlighted the advantage of using cytokinesis as a model system for studying ESCRT mediated membrane fission in a physiologically relevant context. In the proposed project I aim to elucidate how ESCRT function is regulated in cytokinesis in order to unravel the mechanism by which ESCRT proteins drive membrane fission in cells. Using super resolution imaging and quantitative live cell imaging of ESCRT proteins in genetically manipulated cells I will identify factors that regulate ESCRT function in cytokinesis and determine their effect on the spatiotemporal organization of ESCRTs in cytokinesis. Unraveling the regulatory basis for ESCRT function will underlie fundamental steps in the ESCRT pathway required for driving membrane fission in cytokinesis and will contribute critical information for understanding the mechanistic basis for ESCRT mediated membrane fission. The results of this work will have great implication to other ESCRT mediated cellular events including receptor degradation and viral budding.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'ENERGY CORRIDOR OPTIMISATION, FOR THE EUROPEAN MARKETS OF GAS, ELECTRICITY AND HYDROGEN'.

assistant: **Objectives**

Successful integration of energy systems in Europe is deeply depending on the opening up of energy markets in EU and neighbouring countries in the next decades. Since the EU is increasingly depending on imports of fossil energy, electricity and (later) hydrogen, it is clear that these network infrastructures depending trade requires a proper technical, economic and environmental assessment of the potential, benefits and barriers of such energy corridor. Key Objectives:- Assessing economically optimal energy corridors (electricity, natural gas and hydrogen) between EU and neighbouring countries.- Identifying barriers and benefits and recommend policy measures for reaching a pan-European energy network.- Scope Secure consensus among scientists, stakeholders and NGO's on these topics, i.e. by organising regularly workshops to discuss findings and results, invite them to discuss work programme at the kick-off and final report with conclusions and recommendations at a final conference.- Analyse and determine the economic, environmental and socio-economic impacts of the optimum configurations of these energy interconnections.- Disseminate conclusions and recommendations to enforce consensus and concrete actions regarding investment in and changing market policies to increase access to transmission corridors between EU and neighbouring countries and cross border trade in electricity and gas and later after 2020 hydrogen.Approach based on recent studies on the energy corridors we identify and analyse potential and required capacities and routing. We quantify for each energy carrier the optimal configurations and capacities and their impact. Finally per energy carrier follows a final assessment of benefits and barriers and optimised configuration of these corridors. Thereafter a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'The Bilingual SEmaNtic SystEm (SENSE): Computational Assessment of Cross-linguistic Meaning Representation Across Cultures' in the context of a Horizon Europe call.

assistant: **Objectives**

Growing evidence suggests lexical semantics is not universal, being shaped by culture, and translation equivalents may bear distinct meanings in each language. If so, how do bilingual brains juggle competing meaning representations for translations? SENSE will investigate the impact knowing a second language has on the native language's semantic system across cultures.   To do so, we will use two recent computational approaches: distributional semantic and word association models (obtained from linguistic corpora and free association data, respectively). Both methods have shown promising results in predicting human performance in semantic tasks, making them ideal candidates to inform psychological theories. Yet, which models better reflect human semantic representation is under debate. Further, few studies in semantic memory research have used these tools. While researchers have stressed the need to adopt these methodologies, these calls almost invariably have a monolingual scope, neglecting the pressing questions bilingualism poses on the nature of the semantic system.  SENSE has three overarching goals. (1) To assess the role of culture in the construction of meaning by examining the conceptual structure of languages from different primary families spoken in culturally distinct societies (Spanish, Turkish, Chinese). English, the invariable second language, will also be studied. (2) To measure bilingualism's impact on semantic representation by investigating how L2 English semantic information integrates into the already established native language's semantic systems. (3) To test which models are better suited to account for meaning representation by comparing their predictability of human performance in a battery of semantic tasks.   Overall, SENSE will make a solid c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'A Modular Framework for Designing and Producing Biohybrid Machines' in the context of a Horizon Europe call.

assistant: **Objectives**

Bio-hybrid machines (BHMs) combine living cell actuators with artificial materials in order to achieve greater autonomy, flexibility, and energy efficiency compared to standard robots. However, BHMs are developed in silos of individual research groups, making their development more of an art relying on individual knowledge, intuition, and skills than on standardized decision-making processes.To push the manufacturing of BHMs towards bio-intelligent paradigm and model-based engineering, we propose to develop a self-monitoring and self-controlling manufacturing pipeline of BHMs. To realize such a pipeline, we would need to (i) Develop a modeling and simulation framework that will streamline the processes of design, quoting, manufacturing, verification, and reporting, thus significantly reducing error-prone manual steps. Also, given that actuators in BHMs are living cells, which greatly expands the parameter space, we believe that the development of BHMs would greatly benefit from AI-guided modeling process to optimize search for the most efficient design; (ii) To experimentally test, optimize, and verify the platform by developing a proof-of-principle reconfigurable modular catheter BHM; (iii) To group all necessary manufacturing equipment into an integrated bio-intelligent manufacturing cell (BIMC) and demonstrate its adaptable operation.As a proof-of-principle, we will use BHM catheter as it is an innovative medical device that would be able to arrive into hard-to-reach regions of the human body and release drugs there.


**Keywords:** biohybrid machine, cell actuators, machine learning, catheter, manufacturing cell
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Sea ice across Dansgaard-Oeschger events in Greenland' (SEADOG), addressing dissemination and exploitation.

assistant: **Impact**

The Last Glacial climate of the Northern Hemisphere was punctuated by abrupt millennial scale changes called Dansgaard-Oeschger (DO) events, clearly recorded by Greenland ice core temperature proxies. The underlying mechanism responsible for the recurring cycles of ~10°C rapid increase, followed by gradual cooling, remains uncertain. Many studies suggest that large changes in sea ice extent played a major role in their causation.  Sea ice is closely linked to climate; changes in sea ice extent feedback positively on Arctic temperature—a phenomenon of great relevance to the future of Arctic sea ice in our changing climate. This project combines Greenland ice core chemistry records with atmospheric chemistry transport modeling in order to constrain Arctic sea ice variability across DO events.  Records of sea salt (Na+), and methane sulphonic acid (MSA), from four ice cores will be analysed for spatial and temporal variability across DO events. The controls on marine aerosol deposition over the Greenland Ice Sheet will be investigated using a atmospheric chemistry transport model, Cambridge p-TOMCAT, which has been successfully deployed for the Antarctic. The relative influence of sea ice and other factors e.g., meteorology, on ice core chemistry variability will be assessed using sensitivity tests that will also provide an indication of the gross sea ice changes in required to reproduce the significant sea salt changes recorded in ice cores. Furthermore, an atmospheric chemistry transport model, that can be interfaced with fully coupled ocean-atmosphere climate model output, will be optimised according to our findings. This model will be run with palaeoclimatic boundary conditions to obtain scenarios of sea ice change consistent with the ice core chemistry data. Separate
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Concepts and tools in molecular spintronics' (COSMICS) under Horizon 2020.

assistant: **Objectives**

Molecular spintronics is an emergent field combining the flexibility of molecular electronics and and molecular magnetism with the advantages of spintronics. Its main goal is the manipulation of the electron spin by a wise combination of ad-hoc molecules and inorganic substrate. Besides the rich magnetic behavior resulting from the interaction between a magnetic molecule and a metal surface, or vice versa, additional functions such as switchability by external parameters (light, voltage) can be integrated. This multi-disciplinary field offers a wide range of routes towards spin-based devices with potential technological applications in information storage and processing However, due to the very large number of possible material combinations there is an urgent need for fundamental understanding, guiding concepts and tools to scale up and systematize the search of new smart functional molecular designs. Our scientific target is to develop a modelling platform around molecular spintronics that is essential to stimulate fundamental as well as applied/technological research and facilitate the emergence of new key enabling technologies. The novelty of our project is to combine and develop the most up to date modelling tools with cutting-edge well-controlled and calibrated experimental methods in order to unravel the fundamental mechanisms governing the magneto-transport properties in molecular spintronic systems. The modelling tools developed will further be integrated as a molecular spintronic toolkit into a user-friendly software proposed by a fast growing small and medium-sized enterprise (SME) specialized in developing digital applications for the atomistic simulations of materials for technology development. Besides the tools implemented in the course of the project we a