RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Agile Exploration and Geo-modelling for European Critical Raw materials' (AGEMERA) targeting Horizon Europe.

assistant: **Abstract**

New environmental, economic and societal requirements in the EUs transition to a low-carbon and digital economy call for innovative methods, technologies and techniques to be developed and applied in mineral exploration. To unlock the CRM potential in Europe, AGEMERA will conduct local state-of-art geological and geophysical surveys over a total of ~4,700 km2 in order to detailly map CRM resources in 6 EU countries and 1 third country (Zambia). The geophysical field trial surveys will demonstrate three novel non-invasive survey methods (at up to a TRL5) based on remote sensing and related data analysis: 1) passive seismic methods, 2) multi-sensing drone system combining magnetic, radiometric and electromagnetic sensing, and 3) muon-based multidetector density detection system. The project will use data from open-access databases (e.g., European Geological Data Infrastructure, EGDI), the data collected from the field by project geoscientists, and various geophysical survey methods to refine and improve the genetic mineral system models of the various deposit types known to contain lithium, cobalt, molybdenum, vanadium, PGMs, niobium, tantalum, bauxite and REE. The project will introduce the existing guidance for the application of UNFC for mineral resources to the partner countries through stakeholders, courses and public events. The project will survey citizens in the project countries, create a CRM educational package targeting schools and universities, publish an online CRM serious game, organise public events, as well as online news flashes, with the aim to reach 5,000,000 citizens by 2030. The project will create an open-access SoftGIS analysis and database on peoples social, cultural, environmental and economic concerns related to mining and mineral exploration. Th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Microalgae as cell factories for chemical and biochemical products' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

There is increasing interest throughout Europe in alternative methods of obtaining chemical and biochemical products. Scientists are increasingly turning to micro algae as a natural source of many useful products. They also have many other useful properties, e.g. as a food source for humans and animals. There has been considerable research performed throughout Europe into micro algae, but good results have been limited, due to poor co-ordination and duplication of research. The uptake rate of new technology has also been less than impressive. This network will support European research into micro algae and make recommendations for its future direction. It will aid technology transfer between cutting edge research companies and Sees and also lay the groundwork for a micro algal 'virtual institute'.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Development of functional dairy products based on goat milk' (1998-2002) under Fifth Framework.

assistant: **Objectives**

At the European level Greece and France account for 60 % of the goat milk production. Although the breeding systems are quite different in these countries, most of the goat milk is dedicated to the manufacture of traditional products. However, in order to respond to emerging consumers needs and dietary trends, Sees involved in the transformation of goat milk have to diversify their products. The aim of the exploratory phase is to prepare a Cooperative Research Project (CRAFT) that will allow this diversification. Goat milk functionality will be exploited in order to develop innovative products that bring either health benefits or improved convenience for the consumers. The exploratory phase comprises three additional objectives: a feasibility study to evaluate the state of the art in the field of goat milk products, an evaluation of the market potentialities and a novelty verification. Additional partners will be also recruited during the exploratory phase in order to add value to the project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Combined genetic and functional genomic approaches for stress and disease resistance marker assisted selection in fish and shellfish' (AQUAFIRST) targeting Sixth Framework.

assistant: **Abstract**

The overall aim of this project is to identify genes associated with stress and disease resitance in oyster, trout, sea bream, and sea bass in order to provide a physiological and genetic basis for marker-assisted selection. These studies will be carried o ut for fish using stress and pathogen challenges directly relevant to aquaculture and for oyster using environmental conditions that are known to lead to significant summer mortalities. In Part 1 of the project the genes involved in the functional response to stress or pathogen exposure will be identified. This will be carried out in the four species by (i) constructing relevant EST collections using SSH cDNA libraries which will be spotted on microarrays, followed by (ii) analysis of gene expression profil es in various tissues of animals exposed to stressors or pathogens. This analysis will be also carried out in families that are divergent for stress response or disease resistance (fish) or for summer survival (oyster). In order to investigate relationship between potential candidate genes and QTL for these traits, Part 2 of the project will identify Single Nucleotide Polymorphisms (SNP) in these candidate genes in oyster and trout. This polymorphism will be analysed both in the EST sequences and in the pro moter region. In Part 3 of the project QTL analysis will be used to identify genes that are associated with stress specific traits and disease resistance traits using previously characterized SNP and also microsatellites markers. We will also carry out map ping of these genes in linkage and gene maps.Part 4 is devoted to outline operational genetic protocols incorporating identified QTL and traditional breeding approaches in oyster, sea bream and sea bass. This knowledge will be transferred to the industry t hro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Development of high corrosion resistant high strength single crystal superalloys for industrial gas turbine blades' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Objectives and content The aim of this project is to develop new superalloy compositions specifically designed for casting of large single crystal gas turbine blades for power generation. Replacement of conventionally cast blades by single crystal blades would permit an increase of the firing temperature, and consequently a better efficiency of the gas turbine. Other important consequences will be a reduction in fuel consumption and a decrease of the pollutant emission level. The specific working conditions of industrial gas turbines using low-grade fuels require materials with a high corrosion resistance in severe environment, in addition to a good stress-rupture strength with lives up to 50,000 hours, which is different from the conditions encountered in aeronautical gas turbines. Two sets of objectives will be persued corresponding to alloys satisfying the following requirements :i) corrosion resistance in synthetic ash at 700-800°C comparable to IN738LC and creep strength at 750-950°C comparable to IN792, ii) sulfidation resistance at 900-1000°C comparable to IN738LC and a typical stress-rupture life of 3,500 hours at 950°C and 140 MPa. Moreover, the alloys will have to show: i) a good castability as large single crystal components up to 50 cm height, ii) a good long term microstructural stability, iii) cost effectiveness. Needless to say that none of the currently available materials possess this overall combination of properties and therefore there is a strong need expressed by the European gas turbine industry to develop such new superalloys. The first phase of the work programme will include the definition of a set of experimental alloys using alloy design procedures, directional casting of single crystal test-pieces and components, corrosion, mechanical and mic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'ICT in traditional manufacturing industries ERA-Net', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

eTRANET will enable national governments and agencies from 13 countries to increase the national and European impact of their investment in RTD within the domain of 'ICT for Traditional Manufacturing Industries'. Itwill also provide the opportunity for par tners to collaborate on next generation futuristic R&D themes through exchanging best practice, carrying out joint studies/activities, exploiting synergies between programmes and pioneering new approaches to pan-European collaboration. A high-level Net work Policy Group of senior representatives from national government ministries/agencies will meet annually to steer the coordination actions and develop a common agenda for trans-national research. This common agenda will be articulated as a Joint Action Plan by the end of the third year and will be underpinned by pilot projects during the first three years. In addition, members of the Policy Group will prepare for trans-national activities by exploring possibilities for collaboration on specific thematic areas for futuristic RTD. eTRANET aims to launch at least one Joint Call for a trans-national research programme at a European Conference for domain researchers in year three. The consortium has a strong commitment to trans-national collaboration having or iginated from the Synergy Group of the EUREKA FACTORY Umbrella Programme and the TAFTIE Network (The Association For Technology Implementation in Europe). ERA-NET objectives of 'networking of research activities at a national level' and 'mutual opening of national research programmes' are clearly encompassed by eTRANET's five main objectives: 1. Information exchange, sharing best practice 2. Strategic activities between programmes, preparing for eTRANET expansion 3. Joint activities between partners 4. Tran s-nation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Regulation of dopamine transporter function by the PDZ domain protein PICK1' under Seventh Framework.

assistant: **Concept**

The dopamine transporter (DAT) belongs to the family of Na+/Cl- dependent neurotransmitter transporters and is responsible for rapid termination of dopaminergic signaling by mediating reuptake of dopamine (DA) from the synaptic cleft. The DAT is target for widely abused psychostimulants, such as amphetamine and cocaine, as well as modification in DAT activity has been associated with severe brain disorders like Parkinson’s disease, schizophrenia and attention deficit hyperactivity disorder (ADHD). An increasing number of proteins have been identified as interaction partners of the DAT but the functional implications of the interactions are poorly understood. Here we propose to investigate the molecular significance of the interaction between DAT and the PDZ domain protein PICK1. Based on a series of preliminary data we propose that binding of PICK1 via its PDZ domain to the DAT C-terminus operate to regulate uncoupled DAT mediated currents. Notably, these currents are likely to modulate the excitability of dopaminergic neurons and thereby the overall activity of the dopamine system. We hypothesize that PICK1 mediated regulation of these currents either involves enhanced DAT phosphorylation due to PICK1 mediated recruitment of protein kinase Ca or modulation of intramolecular interactions in the transporter molecule. We will test our hypotheses by employing an interdisciplinary strategy that combines the expertise of the applicants with those of the host laboratory and involves a broad spectrum of methods including patch clamp measurements, bioimaging and molecular biological procedures.  We expect that the project will lead to significant improvement of our understanding of DAT regulation and thereby provide an important framework for future discovery of novel therapeut
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Asymmetric Csp3 – Csp3 Suzuki−Miyaura Coupling Employing 1,1-Bisboryl Alkanes' under Horizon 2020.

assistant: **Concept**

Suzuki−Miyaura coupling (SMC) has emerged as a powerful strategy in the field of cross-coupling reactions and is widely used in synthetic organic chemistry and drug development. Asymmetric SMC reactions employing aryl/alkenyl boronic acid is well developed; however, no general Csp3 – Csp3 Suzuki-Miyaura coupling is currently available. Furthermore, the asymmetric addition of benzylic nucleophile or 1,1-difunctionalized reagents as a nucleophile is quite rare. This proposal aims to develop a general cross-coupling procedure that will effectively allow the use of 1,1-bisboryl alkanes in asymmetric SMC reactions. We intend to utilise the rhodium and copper catalysed dynamic kinetic asymmetric transformations (DYKAT) protocol developed in the Fletcher group to achieve this transformation. The corresponding enantioenriched product would feature boronic ester moiety equipped for further modification. Furthermore, the transformation would serve as an alternative protocol for the addition of difficult to install benzylic group. The method would provide a significant advancement in asymmetric cross-coupling reactions and would fortify the broad applicability of DYKATs in SMC reactions in the field of synthesis, medicinal and materials chemistry.


**Keywords:** Asymmetric Catalysis, Suzuki-Miyaura Coupling, DYKAT, Organoborones
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Selection efficacy at intraspecific and interspecific scales: insights from haplo-diplontic plants'.

assistant: **Concept**

Natural selection is a pillar of evssNatural selection is a pillar of evolutionary biology: it tends to fix beneficial mutations and remove deleterious ones. But the factors that determine selection efficacy are yet poorly understood. A proposed factor is the interaction between mutations? dominance and ploidy level: recessivity should reduce selection efficacy in diploids but not in haploids. Methodological limits make this challenging to test in species with a diploid-dominant life cycle. Yet, a whole phylogenetic clade under-explored in genomics gathers all the attributes to tackle this question: Bryophytes. Their life cycle is characterized by alternating a long haploid phase (gametophyte) with a short diploid phase (sporophyte), both phases being macroscopic. It is ideal for shedding light on what drives selection efficacy within and between species; thus, improving our understanding of adaptation and speciation.1 How ploidy affects the efficacy of adaptive and purifying selections within species? Using comparative genomics, I will empirically test i) if selection is more efficient for haploid-biased genes (i.e., expressed primarily in the gametophyte) than diploid-biased genes, and ii) if that difference is reinforced in species with a more complex sporophyte.2 How ploidy affects the efficacy of selection against hybridization between species? With theoretical developments, I will quantify the extent to which the length of gametophytic and sporophytic phases influences the rate of accumulation of reproductive barriers against interspecies introgression. These predictions will be confronted with genomic estimates by developing a statistical inference method.3 How efficient is selection in non-recombining genomes? I will take advantage of the Bryophytes? U/V sexual
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Consequences of out-group conflict' to be submitted under Horizon 2020.

assistant: **Abstract**

The aim of this project is to determine the proximate and ultimate consequences of a fundamental but neglected aspect of sociality: out-group conflict. In a wide range of social species, from ants to humans, group members invest considerable defensive effort against individual intruders and rival groups. The lasting impacts of these conflicts with conspecifics are poorly understood. I will integrate empirical and theoretical approaches to uncover the effect of out-group conflict on: (i) individual behaviour, within-group interactions and group decision-making; (ii) steroid hormones that underlie stress, social behaviour and reproduction; (iii) variation in reproductive success arising from maternal investment and offspring care; and (iv) the evolution of societal structure, cooperation and punishment among group-mates, and weaponry and fortification. I will achieve these ambitious objectives using proven experimental paradigms, innovative non-invasive sampling, long-term monitoring, and state-of-the-art analytical methods to collect data from two highly tractable model systems that I have established over the last 4 years: a captive-breeding population of the cichlid fish Neolamprologus pulcher and a habituated wild population of dwarf mongooses (Helogale parvula). I will use some of the same data to inform the assumptions of mathematical models and evolutionary simulations in the development of a rigorous, predictive framework on out-group conflict, which I will test using both my model systems and phylogenetically controlled meta-analyses across species. The management and consequences of conflict are of major importance to science, human society and global politics. My novel and inter-disciplinary proposal will not only significantly advance our understanding of the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Science Transformation in EuroPe through Citizens involvement in HeAlth, coNservation and enerGy rEsearch' (2014-2020) under Horizon 2020.

assistant: **Objectives**

STEP CHANGE (Science Transformation in EuroPe through Citizens involvement in HeAlth, coNservation and enerGy rEsearch) replies to the H2020 Topic SwafS 27 on “Hands-on citizen science and frugal innovation”, Sub-topic A, citizen science. The project, coordinated by the University of Primorska,  is based on the assumption that citizen science (CS) can play an even broader societal and scientific role than it is generally acknowledged, particularly in those critical fields of research (like Energy, Health and the Environment) where human and non-human factors are deeply entangled.  In these areas, a set of highly-contested, socially relevant research fields is emerging where CS can play a pivotal role by making science more socially robust, inclusive and democratic while strengthening the capacity of scientific investigation over emerging phenomena that cannot be easily caught within narrow disciplinary boundaries. Then, STEP CHANGE was designed to contribute to making the most of CS potentialities, while at the same time identifying, analysing, and tackling such limitations and risks. In this regard, STEP-CHANGE is based on the implementation of five Citizen Science Initiatives (CSIs) in the areas of Energy, Environment, Health and Infectious Diseases, through the participatory and self-reflexive analysis and evaluation of their collaborative research processes, scientific outcomes and societal impacts. The CSIs regard: 1) wildlife conservation in Slovenia (UP); 2) non-alcoholic fatty liver disease in the UK (TGI, NIHR and OUXF); 3); energy communities in Germany (WECF);  4) infectious disease outbreak preparedness in Italy (UNITOV); 5) off-grid renewable energy in agriculture in Uganda (ARUWE). Horizontal activities are also foreseen: Scoping process (SfC), Participato