RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Climate Tipping Points: Uncertainty-aware quantification of Earth system tipping potential from observations and models and assessment of associated climatic, ecological, and socioeconomic impacts', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The likelihood of large-scale Earth system tipping events under ongoing anthropogenic forcing remains uncertain. In view of the possible irreversibility associated with such events and the potentially catastrophic global consequences on climate, ecosystems, and society, the precautionary principle demands thorough investigation of the underlying mechanisms, compound or cascading impacts, and associated risks. ClimTip will substantially advance the process understanding of possible Earth system Tipping Elements (TEs). It will provide the methodological framework for characterising and constraining potential TEs from paleoclimate, observational and model data, for identifying unknown tipping potential from observations and models, and for quantifying resilience and changes thereof in climate and ecosystems, including early-warning of forthcoming transitions. Earth system models (ESMs) are the primary tool for projecting the risk of large-scale tipping events and ClimTip will substantially improve their representation of suggested TEs. This will enable the identification of safe operating spaces for a stable Earth system by characterising key Earth system TEs in terms of their critical thresholds and rates, hysteresis and overshoot potential via empirical data and ESMs, taking into account the associated uncertainties. As a unique climate service, ClimTip will provide global high-resolution bias-corrected climate fields for large-scale tipping events based on storylines of tipping in comprehensive ESMs. The associated impacts on climate, ecosystems, biodiversity, agriculture, society and economy will be assessed globally and put in relation with the Paris Agreement and the EU Biodiversity Strategy 2030. ClimTip will deliver a comprehensive and precise knowledge basis for t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'All-Dielectric Reconfigurable Metasurface with Electrical in-situ Switching Using Phase Change Materials' (DReM-PCM).

assistant: **Innovation**

All-dielectric optical metasurfaces have  recently  attained much attention due to their ability to provide higher efficiencies than the more conventional plasmonic metasurfaces, and for their ability to readily work in both reflection and transmission. However, the functionality of traditional dielectric-based metasurfaces is fixed-by-design, i.e. the optical response is fixed by the size, arrangement and index of the nanoresonators. A far wider range of applications in many important technological/industrial fields, ranging from communications, to sensing, robotics, displays and much more, could be addressed if active/reconfigurable control were possible. One promising all-dielectric reconfigurable metasurface approach arises from the combination of high-index dielectric nanostructure arrays with chalcogenide phase-change materials (e.g. GeSbTe alloys). The latter can be electrically, optically or thermally switched between their crystalline and amorphous states, or to intermediate states between the two, with ultra-low energy consumption in a non-volatile manner and exhibit remarkably different optical properties between phases. It is therefore possible to achieve an all-dielectric reconfigurable metasurface by continuously tuning the phase states of the chalcogenide alloy. However, very few dielectric metasurface designs incorporating phase-change materials have been explored to date, and those that have been reported are switched through ex-situ means, while some form of in-situ switching is definitely required to meet real device applications.To achieve this objective, we will (1) theoretically design and  experimentally fabricate two reconfigurable all-dielectric phase-change metasurfaces whose in-situ switching  is electrically realised by an integrated microhea
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Reliable Integrated On-Line Characterisation Tool for Thermoplastic Compound' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The SME-driven NanoOnSpect project aims to accelerate the commercialisation of innovative polymer nanocomposites (PNCs), combining developments in online sensor technology, artificial intelligence-based signal analysis and real-time process optimisation to create a comprehensive solution to quality problems.NanoOnSpect has 3 development aims:1) Newly-developed online characterisation techniques will be combined in a ""one-box"" characterisation unit. This will be able to determine dispersion, particle size, particle network formation and resulting composite properties online under demanding industrial conditions, with a (factor 2 to 10) higher resolution than conventional online characterisation tools.2) An Artificial Neural Network and Expert System (ES) module will be developed to analyse sensor signals, predict the complex quality of the PNC and calculate new input parameters for the compounding line.3) A breakthrough concept will be developed to adapt the mixing process during composite production, based on feedback from the ES.The characterisation tool and process control technique will allow precise adjustment of the composite properties (e.g. dispersion-dependent properties) during production. This will improve product quality, allow the reliable production of PNCs with tailored functions and reduce waste production. The technology will be validated in existing production lines for two particle types. NanoOnSpect will also deliver in depth understanding of materials and processing, shortening material development cycles and formulation changeovers.The NanoOnSpect consortium, consisting of 8 SMEs, 2 RTD performers and 2 associations, combines competences in measurement technology/automation, polymer processing technology, end use and demonstration, standardisation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The Underbelly of the Indian Boom: Adivasis and Dalits' (UNDERINDIA).

assistant: **Concept**

In recent decades India has experienced exceptionally high economic growth rates, becoming one of the world’s fastest growing major economies. Yet, the redistribution of the fruits of economic growth – the trickle down effects of growth – have been negligible for vast swathes of India’s population, most of who live in the countryside. The demographics of the poor are starkly socially marked. Economists tell us that India’s dalit and adivasi communities, who account for almost 25% of the country’s population and were historically seen as ‘untouchable’ and ‘savage’, suffer from disproportionate levels of poverty, remaining worse off than other groups almost everywhere across the country. But econometric analysis is unable to tell us how and why this is the case. This project uses an innovative anthropological approach to understand the processes by which poverty is reproduced through agrarian relations and the shift from farm-based social and economic hierarchies towards new forms of power and exploitation off the farm which lead to the persistence of dalit and adivasi marginalisation across India. Informed by recent statistical research and policy shifts at the national and state levels, this project will craft a more critical and powerful alternative to poverty measurements by ethnographically exploring the relationship between political and economic transformations in rural-based dalit and adivasi lives, and the transformations taking place at the macro level. It thus establishes a new methodological field which structures ethnography in the framework of political economic theory and brings this combination to the centre of understandings of poverty. It will provide the first historically situated ethnographic studies which are comparative, not only in their regional d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Sarcoma as a model to improve diagnosis and clinical care of rare tumors through a European and Latin American multidisciplinary network' (SELNET), addressing dissemination and exploitation.

assistant: **Impact**

Rare cancersRare cancers are associated with poor survival, accounting for 22% of new cancer diagnoses in Europe, and 30% of cancer deaths. Sarcomas are a heterogeneous group of life-threatening rare solid malignancies affecting soft and bone tissues, representing 10% of rare tumors and around 2% of adult tumors, with an incidence of 5.9/100,000/year in Europe. Appropriate management of sarcoma patients is hindered by the absence of referral policies to reference centers (RCs), incorrect or delayed diagnosis, non-adherence of therapies to clinical practice guidelines (CPGs), and lack of expertise by practitioners, which increases the risk of relapse and death. These problems worsen in the Community of Latin American and Caribbean States (CELAC) due to the scarcity or complete unavailability of RCs, expert pathologists, multidisciplinary tumor boards (MTBs), new cancer drugs, clinical trials, patient registry data, and financial resources. Hence, the SELNET project seeks to create a European and Latin American multidisciplinary network of clinical and translational specialists to improve diagnosis and clinical care in sarcomas, with the aim of validating a collaborative model replicable in other rare tumors and in other countries. Recognized cancer centers and research groups of Spain, Italy, France, Mexico, Brazil, Argentina, Costa Rica, and Peru will contribute to better rare cancer care by fostering RCs, healthcare barrier analysis, CPGs, and medical education as key improvement drivers. The core of the research work focuses on improving diagnosis and prognosis of sarcoma patients through the creation of pathological diagnosis networks, MTBs, the conduct of an international registry-based observational study to assess clinical management quality and prognostic factors
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'COllaborative Management Platform for detection and Analyses of (Re-)emerging and foodborne outbreaks in Europe'.

assistant: **Innovation**

COMPARE aims to harness the rapid advances in molecular technology to improve identification and mitigation of emerging infectious diseases and foodborne outbreaks. To this purpose COMPARE will establish a “One serves all” analytical framework and data exchange platform that will allow real time analysis and interpretation of sequence-based pathogen data in combination with associated data (e.g. clinical, epidemiological data) in an integrated inter-sectorial, interdisciplinary, international, “one health” approach. The framework will link research, clinical and public health organisations  active in human health,  animal health, and food safety  in Europe and beyond, to develop (i) integrated risk assessment and risk based collection of samples and data, (ii) harmonised workflows for generating comparable sequence and associated data, (iii) state-of-the-art analytical workflows and tools for generating actionable information for support of patient diagnosis, treatment, outbreak detection and -investigation and (iv) risk communication tools. The analytical workflows will be linked to a flexible, scalable and open-source data- and information platform supporting rapid sharing, interrogation and analysis of sequence-based pathogen data in combination with other associated data. The system will be linked to existing and future complementary systems, networks and databases such as those used by ECDC, NCBI and EFSA. The functionalities of the system will be tested and fine tuned through underpinning research studies on priority pathogens covering healthcare-associated infections, food-borne disease, and (zoonotic) (re-) emerging diseases with epidemic or pandemic potential. Throughout the project, extensive consultations with future users, studies into the barriers to open d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Preventative OperationaL procedures for space weAtheR threats to CrItical InfraStructure' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Protection of critical infrastructure in particular in the areas of energy/transport and communication grids is now crucial within our highly technical dependent societies. The scope for this project is to focus on the development of a commercial service offering to operators of such critical infrastructure which provides preventative operational procedures tailored to their individual needs. The operational procedures are based upon threat assessments received from external sources and in this proposal we are focusing on the initial threat detection which shall be incorporated into the service which is based upon Space Weather analysis.Space weather can have detrimental, and in some cases catastrophic, effects upon critical infrastructure on which we depend as part our daily lives. Adverse space weather has dramatically different effects on these the services provided by such critical infrastructure based on the underlying technologies in use and there location. For example a power transmission network operator in high latitudes and a traffic flow monitor network operator is low latitudes have completely different preventative operational procedures and space weather concerns. An operator therefore needs to understand the impact for their facility on a threat, an expert analysis and interpretation on a received threat and be informed in terms the operator understands on the steps required to prevent the threat escalating to become a major issue.Currently only global forecasts and information on the type of space weather events are available, missing the vital links between space weather and the operational procedures to mitigate the threat for a particular operator.We therefore propose to develop a system and a service offering titled, POLARIS, that will provide a sing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Acceptance, Safety and Sustainability Recommendations for Efficient Deployment of UAM' under Horizon 2020.

assistant: **Concept**

Rapidly developing technology in recent years, makes the concept of vertical transport over populated areas real and nearly ready for implementation. The vision of additional dimension added to hitherto nearly flat urban/metropolitan transport system own potential to become a mobility revolution for passengers and unprecedented challenge for cities in numerous aspects. ASSURED-UAM (Acceptability, safety and sustainability recommendations for Efficient Deployment of UAM) aiming at assuring outstanding robustness in terms of safety, sustainability and acceptability of UAM by focusing to: propagate and accommodate aviation best practices, standards, recommendations and organizational solutions into city/municipal administrative and legislative structures responsible for deployment Urban Air Mobility services in near future; To assure broad and comprehensive organisational and policy definition support for authorities, policy makers and urban industry organization in complex process of implementation of vertical modes of transport and integration with horizontal dimensions of urban and peri-urban mobility systems; To become first but robust answer on European Green Deal goals contributing to climate neutral urban transport in 2050; To provide recommendations for integration of surface modes under the umbrella of U-Space Air Traffic Management System (X-TEAM D2D Project). Outline: Multidisciplinary study providing organizational and policy framework for process of introduction of  unmanned modes of urban air mobility. In detail: ConOps, Plan for deployment scenarios for 10 use cases within 5, 10 and 15-year’ timeframe, Knowledge base and policy recommendations in 8 languages, standards for products and processes as well as tools for exchange and learning of urban air mobilit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Resistance in Gram-Negative Organisms: Studying Intervention Strategies' (R-GNOSIS), addressing dissemination and exploitation.

assistant: **Impact**

Antibiotics are a mainstay of public health, but their use has increased exponentially leading to the emergence of antibiotic resistance. The R-GNOSIS (Resistance in Gram-Negative Organisms: Studying Intervention Strategies) project combines 5 international clinical studies, all supported by highly innovative microbiology, mathematical modelling and data-management, to determine - in the most relevant patient populations - the efficacy and effectiveness of cutting-edge interventions to reduce carriage, infection and spread of Multi-Drug Resistant Gram-negative Bacteria (MDR-GNB). All work-packages will progress science beyond the state-of-the-art in generating new and translational clinically relevant knowledge, through hypothesis-driven studies focussed on patient-centred outcomes.The 5 clinical studies will investigate the following interventions:•A Point-Of-Care-Testing guided management strategy to improve appropriate antibiotic prescription for uncomplicated UTI in primary care.•Gut decolonization in outpatients with intestinal carriage of MDR-GNB.•A “test and prescribe” strategy, based on rapid diagnostic testing of faeces for MDR-GNB to optimize antibiotic prophylaxis in colo-rectal surgery.•Contact Isolation of patients with ESBL-producing Enterobacteriaceae in general hospital wards.•Three Decolonization strategies in ICUs.Seven laboratories across Europe will perform microbiological analyses, as well as unique quantitative experiments. All information will be integrated by 3 groups of mathematical modellers into highly innovative models to better understand and predict future trends and effects of interventions. The studies and analyses proposed in R-GNOSIS will generate a step-change in identifying evidence-based preventive measures and clinical guidance for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Iessia' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

The outcome of this proposal will be a series of three very high level Euro Summer Schools in Mathematical Analysis. The principal aim of this series is the training of Young Researchers from the EU and Associated States for the beginning of the next century.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Paleo-Evolutionary Medicine: Using ancient DNA to study the origins of common complex diseases'.

assistant: **Innovation**

Common diseases, such as cancer, dementia and heart disease, are the leading causes of death globally. In the UK, it is estimated that 1 in 2 people will develop cancer in their lifetime, 1 in 3 will develop dementia, and 1 in 4 will die from cardiovascular disease. However, the risks of developing common diseases are not shared equally between individuals or populations. Genetic susceptibility to disease is a major contributor to disease prevalence, alongside diet, lifestyle and other environmental factors. Understanding the genetic component of disease risk is a critical issue in epidemiology, as it directly informs public health policy, disease prevention and the development of vaccines and novel therapeutics. Most of the existing research in this area has focused on the underlying genetics of risk, while relatively little is known about the evolutionary origins of common diseases. This is a major omission, as understanding the origins of genetic risk can improve health outcomes in the present.In this ERC Starting Grant, I will use ancient DNA to model the evolutionary origins of genetic susceptibility to the leading causes of death and ill health worldwide, including cancer, dementia, cardiovascular, metabolic, autoimmune, respiratory and infectious diseases. I will build and apply state-of-the-art computational tools to (i) model the effects of natural selection on disease risk in the human genome; to (ii) reconstruct the evolutionary history of human and zoonotic pathogens; and to (iii) model the effects of pathogens, and other environmental factors, on the evolution of human disease susceptibility.


**Keywords:** Evolutionary Medicine; Ancient DNA; Complex Traits; Polygenic Adaptation; Infectious Disease;