RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Cajal-Retzius cells role in the development of the spatial navigation system' (CaRe-Space).

assistant: **Innovation**

Cajal-Retzius (CR) cells play a pivotal role in the development of cortical areas, by guiding the migration of principal cells. While cortical CR cells disappear soon after birth, these cells are present in the hippocampus for several months of postnatal development. However, the role that CR cells play in hippocampus-dependent memories is still unknown. In fact, thehippocampal-parahippocampal region forms a network responsible for spatial representation, in rodents and in humans. In both species, spatial navigation shows a delayed postnatal maturation, which correlates with the persistence of CR cells. CR cells are indeed located in a key position to control the development of the entorhinal-hippocampal connections, and I have previously showed that CR cells are an active part of the hippocampal circuit. I hypothesize that hippocampal CR cells play afundamental role in the maturation of the circuits of the hippocampal region and in the development of the spatial navigation system. By using specific genetic and molecular tools, I will ablate hippocampal CR cells at early postnatal stages and then analyze alterations of the circuit of the hippocampal region and of the spatial navigation system.The last decade has seen a major global effort in trying to understand how the brain processes information. Indeed, several research groups are investigating how spatial maps are created in the brain. However, few studies have looked at how the involved circuits actually develop and what are the consequences of an improper maturation. My previous researchexperience on the development of neuronal circuits and specifically on CR cells will benefit me tremendously in understanding how these cells are contributing to the creation of spatial memory. The study will also help bridging a g
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Parasites of parasites: LARD retrotransposons and genome dynamics' (RETRONOMICS).

assistant: **Concept**

Transposable elements are the main component of higher genomes. The LTR retro-transposons replicate via RNA intermediates, and resemble to retroviruses in both structure and life cycle. The active ones encode the Gag protein, which packages the elements int o Virus-Like Particles (VLPs, assembled from multiple Gag units), and the Pol poly-protein, which allows reverse transcription and integration. The LARDs are non-autonomous LTR retro-transposons, and do not encode these proteins. They are able to transpose, probably by parasitizing active partners, as do defective interfering particles on retroviruses in animal cells. This project aims to study the mechanism of such hyper-parasitic elements, using the LARD within the large Triticeae genome as a model. The fir st objective is to find the autonomous partners, using four integrated approaches. Bioinformatics and PCR analyses will inform about the potential partners for the reverse transcription, and cellular biology and one-hybrid methods about the potential partn ers for the packaging. The second objective is a functional genomics analysis of the dynamic interactions of LARDs with their active partners, by identifying the keys sequences for the packaging and LARD inhibitive activity regarding their active partners. The final objective is a survey on the abundance and the sequence evolution of the key domains of the LARDs and of their active partners, to shed light the evolution way of the LARD, their generalist vs. specific parasitic activity and the co-evolution of such genomic host-parasite interactions. Fundamental questions on parasitic behaviour in the genome, on host-parasite interactions as on the mechanism of trans-complementation of non-autonomous retro-elements will be addressed. Generic applications include
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Secure management of IoT devices lifecycle through identities, trust and distributed ledgers' under Horizon 2020.

assistant: **Concept**

ERATOSTHENES will devise a novel distributed, automated, auditable, yet privacy-respectful, Trust and Identity Management Framework intended to dynamically and holistically manage the lifecycle of IoT devices, strengthening trust, identities, and resilience in the entire IoT ecosystem, supporting the enforcement of the NIS directive, GDPR and Cybersecurity Act. ERASTOSTHENES will leverage breakthrough solutions: (a) the first-ever enclosure of cybersecurity features in IoT devices through deployment of Trust Agents and continuous trust evaluation within the network in a contextual and social approach; (b) decentralised identity management mechanisms to conciliate requirements of self-sovereignty and privacy preservation in a distributed/transparent trust model along with disposable identities; (c) self-encryption/decryption at device-level with a whole system automated recovery process (incl. software, crypto-key material, identities) after an attack based on a multi-layer recovery model; (d) threat-analysis models based on federated learning and edge execution to continuously monitor devices and detect attacks; (e) collaborative IoT threat intelligence sharing across ledgers to adapt detection/defense mechanism to the evolving security conditions and assist the IoT life-cycle; (f) integration of Physical Unclonable Functions in trust framework and distributed ledgers. Finally, it will support enforcement of the NIS directive with a security information sharing mechanism based on inter-ledger technologies to support exchange of trust and security information among stakeholders, enhancing collaboration, vulnerabilities’ disclosure, and secure management of software updates. The overall vision of ERATOSTHENES is to provide core cybersecurity features to be adopted by manu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Planning and Evaluation Methodologies for Mental Healthcare Buildings' to be submitted under Horizon 2020.

assistant: **Abstract**

The study of psychiatric facilities is major for the care of vulnerable people. It is central to the study of therapeutic environment for mental health, great value for understanding mental illness and the psychosocial impact of the built environment and formulating interdisciplinary relations between architecture and health. In Europe, about 20% of the burden of disease relates to mental illness. With low diagnostic and low medical treatment accuracy factor, environment is key for quality of care and patients’ social re-integration. The key questions of this proposal are: (i) how the mechanisms of the environment influence the personal and social milieu of psychiatric space, and (ii) how the environmental needs of the mentally ill are met by wards. Work in other healthcare settings has shed some light on the first, yet little is known about the second. For these, the researcher aims to exploit the scientific tools of architectural morphology (Space Syntax) and juxtapose them with a patient-focused, model for the evaluation of psychiatric environment (the SCP model), to investigate environment in an integrated way. The research will be comparative of two methodologies and will involve facilities in the community as case studies for its physical locus. Those will be examined for their spatial qualities. The findings could set the framework for a model for evidence-based healthcare architecture to serve as design and evaluation tool, immediately accessible to architects and stakeholders. The final product will be design methods and guidelines for healthcare architecture and in particular for community psychiatric facilities immediately accessible to architects. The research is expandable, when environment is important in prevention and care strengthening the area between
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Earth Observation by Autonomous Solar UAV' under Horizon 2020.

assistant: **Concept**

XSUN develops an innovative autonomous solar drone dedicated to earth observation. Inspired from satellite earthobservation, XSUN aims to offer affordable earth data acquisition performed by unmmaned autonomous vehicules to arange of end users which have all express their support to the SolarXOne project : Linear infrastructure observation (such asrailway, pipeline or electrical grid), environmental & security surveillance issues (forest fire detection, traffic surveillance),Maritime observation (traffic surveillance, fishing surveillance), precision agriculture (monitoring of the health of crops andlivestock). A first autonomous prototype is ready (TRL6). Thanks to a patented double-wing innovative design, theperformances of SolarXOne are disruptive compared to existing solutions: large payload capacity (7kg) enabling to carry awide range of data acquisition sensors, very stable flight enabling precise data acquisition, long flight (>600 km / Day),cheaper price for end user compared to competitors. A world record of autonomous solar flight will be tempted in the nextmonths. SolarXOne project objectives are to industrialise the drone production with enhance performances. Adaptability toHydrogen energy source will be added as well as vertical take-off capability. Market demonstration will be done during theproject for linear infrastructure, fire detection, maritime surveillance and precision agriculture. Two operating centres will beopened in France and Germany. XSun is based on 2 complementary business models: earth data service commercializationoperated from the control centres and complete system commercialization. Market analysis have been performed for eachsegment and the business plan shows promising revenue reaching 30 M€ in 2025. XSUN has been created in 2016, it
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Safe and High Quality Food Production using Poor Quality Waters and Improved Irrigation Systems and Management', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

The present proposal addresses two fundamental problems that over the past decade increasingly have become concerns of the general public: the one problem being the jeopardizing of safety and quality of our food products, while the other being the increasing competition for clean fresh water.The proposed project has a multi-disciplinary approach, which integrate the European as well as the global dimension of the EU-policy on food quality and safety. The main driving force behind the project idea is new research results that demonstrate irrigation pattern can increase the water use efficiency as well as the quality of vegetable crops. Furthermore, have recent innovations in the water treatment and irrigation industry shown potential for the use of low quality water resources, such as rivers and other surface water, for irrigation of vegetable crops without jeopardizing food safety or quality.The proposal includes three components:1) The technological development of water saving irrigation systems and management for use of low quality water resources. Technological advances will be made in the field of cost effective tertiary water treatment technology for on-farm use. Irrigation equipment for sub-surface irrigation systems will be tested in the field and developed to facilitate a new water saving strategy, PRD-irrigation, which improves water use efficiency and the quality of the produce.2) Impact of the technology on product quality and safety, production system and the environment as well as a risk assessment from farm to fork.3) A component concerning the feasibility and application of the system.The financial and economic aspects will be investigated and institutional and consumer barriers will be identified. Decision Support System will be developed for the on-farm
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'STEam And Management Under Pressure'.

assistant: **Concept**

The industrial sector could reduce its energy use by at least 13%. 75% of the potential savings can be found in steam and electric motor systems. Actions to tap the full potential in steam systems have been taken in the past but without success since findings from energy audits were not, or partly, implemented. The following barriers have been identified: There is no business case for steam saving measures for enterprise decision makers; There is a lack of technical (steam) expertise of energy auditors and within enterprises generally; There is no formal organisational structure for dealing with energy efficiency (energy management).The objectives and goals of the STEAM-UP proposal are: • Bridging the gap between audit results and implementation by developing an in-depth steam audit covering: state of the art steam expertise; involvement of all stakeholders in the enterprise; identification of non-energy benefits to strengthen business cases; energy management to secure prolongation.• Reducing the effort for measure implementation by developing an integrated solution for business case reporting  and energy management implementation.• Achieve energy savings during this action of 55,6 GWh/a through piloting 75 of the in-depth steam audits. • Building capacity amongst 400 energy auditors for the use of the in-depth steam audit methodology in their daily practise.• Building capacity amongst stakeholders in 75 enterprises on steam and the business benefits to increase steam efficiency.• Building capacity amongst 40 energy management training providers to enable integration of the in-depth steam audit methodology in regular energy training programmes. • Promote knowledge transfer on steam and the benefits to increase steam efficiency. This project focuses on the large,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Training site in : basic mechanisms of amino acid neurotransmission'.

assistant: **Concept**

For the period 2002 - 2005 a limited number (approximately 8) of short term (3 - 12 months) fellowships are available for student who wish to take a PhD in Neuroscience and related fields, and want to do part of the studies at the Marie Curie Training Site in Basic mechanisms of amino acid neurotransmission, Oslo, Norway. We provide training, inter alias, in the following methodologies: Protein purification and analysis, protein-protein interaction, cell and tissue cultures, mamalian transgenic models / molecular genetics, electro physiology, mathematical models, immunocytochemistry including post embedding immunogold quantification, electron microscopy, confocal laser scanning and multiphoton microscopy, flash photolysis, digital imaging, neuroinformatics, computational neuroscience. The fellows will have the opportunity of using the methods for their own projects, but will be encouraged to link onto ongoing research projects at the Training Site. These include studies on embrane proteins transporting amino acids (glutamate, aspartate, glutamine, GABA, glycine, alanine) and potassium channels. The fellowships are available throughout 2002 - 2005. Equal opportunities for female and male students will be actively pursued. The training site is located at the Institute of Basic Medical Sciences, University of Oslo. The monthly grant is EURO 1200. Enquiries: Dr.J. Storm-Mathisen (coordinator), +47851258, jonsm@pons.uio.no Send applications to BAMAN, POBox 1105 Blindern, N-0317 Oslo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Efficient, Modular and LigthWeight Electromagnetic Induction Based Ice Protection System' (InductICE).

assistant: **Concept**

The general goal of the Project is to reach an efficient, modular and lightweight electromagnetic induction based ice protection system, which uniformly heats the wing leading edge surface. One of the main objectives of the induction based ice-protection system is to achieve at least a 95% heating efficiency. In addition to efficiency, ice-protection system speed is essential in order to act on time and accurately without excessive on-board system consumption. Therefore, another one of the objectives of this project is to improve the speed, while providing a precise and targeted control of the generated heat facing the drawbacks of current on-board ice-protection systems. Finally, the weight of the whole solution must be minimized, essential in on-board aircraft systems. The final objective is to reach an ice-protection system with at least the same weight as current on-board ice-protection systems or on the contrary, the sum of its weight and its impact on on-board resources due to its high heating efficiency must be at least equal to current ice-protection solutions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Set up of a standard method for quantitative depth profile analysis of Zn-based coatings by Direct Current Glow Discharge Optical Emission Spectroscopy' under Fourth Framework.

assistant: **Concept**

For the determination and control of composition, coating weigth and thickness of zinc based coatings on steel, the need of a simple analytical method has been highlighted by ECISS TC20 In answer to this need, the general aim of this project is to develop a new standard method, which can become a European Standard, that permit a rapid multielement depth profile and thickness analysis of Zn-based metallic coatings on steel, based on direct current glow discharge optical emission spectrometry (GD-OES). Furthermore, the aim is to develop guidelines for the use of the new method according to quality assurance criteria. Technically, the method should be capable of fulfilling the following requirements: Maximum penetration depth 100 !lm, Multi-element capability of >10 elements in one measurement, Quantification of major and minor elements (0.1%) with an accuracy better than 10%, Analysis time of typically a few minutes. Recent research by the proposers and others, have led to the establishment of a basic technique for quantitative depth profile analysis by GD-OES using the DC (direct current) source, which has been successfully tested in laboratory scale for several applications, including Zn-based coatings. In the proposed project, this technique will by taken one step further in order to establish a standard method for specific applications, namely Zn-based coatings on steel. In order to accomplish this, it is first necessary to carry out more detailed research and method investigations, particularly with respect to calibration procedures and the influence of various instrument-specific parameters. One reason for this is the fact that a number of different instruments exist on the market, and they are not technically identical. The research work will be carried out by the