RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Innovation and opportunity in the evolution of life' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The aim is to produce a complete evolutionary tree of tetrapods and use this to explore two core questions in macroevolution: the balance between innovation and external processes in driving the evolution of life; and, identifying the best model for morphological evolution. Biodiversity today is unbalanced, with a small number of highly successful groups, like birds and beetles, and many others of equal antiquity but with far fewer species. Why are those groups so successful – was it chance or do they have some remarkable adaptation(s)? The core of the project is to construct a complete evolutionary tree of all 30,000 living species of tetrapods (amphibians, reptiles, birds, mammals) and add the 10,000 fossil species; this will generate a database of key characters, the homologies, shared by major groups. The probability of different drivers of diversification will be tested, focusing on those key, highly successful groups (e.g. lizards, birds, neornithines, passerines, rodents) that show explosive evolution to very high species diversity. The proposal goes to the roots of macroevolutionary understanding, and encompasses key questions about origins and modern biodiversity. The project is ambitious, but is possible because of advances in knowledge of relationships of all key tetrapod groups based on phylogenomic and morphological data, increasing precision of geological dating, and the availability of a range of computational methods to construct large phylogenetic trees, to assess likelihood of trees, to explore innovation and evolutionary rates and models, and Bayesian modelling techniques that can map trait data onto large trees and evaluate multiple models of drivers and bias. A unique outcome will be the chance to explore waiting time between major morphological cha
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Creating the technology for safe, long-term carbon storage in the subsurface', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

CarbFix is a combined industrial/academic research program created to 1) increase measurably our understanding of the long-term fate of CO2 injected into the subsurface, 2) develop new technology to facility the safe and permanent of geologic carbon storage, and 3) publicise the results of this research allowing them to be applied internationally.  Unique to CarbFix its running of the Hellisheidi CO2 injection pilot plant, the world’s first CO2 storage project aimed at optimizing CO2 mineral carbonation in the subsurface. This pilot plant allows CarbFix to develop, test and demonstrate to the public novel injection and mentoring methods illuminating the fate of injected CO2.  The CarbFix research program combines observations from the Hellisheidi power plant and the Compostilla EEPR site with laboratory based experiments, study of natural analogs, predictive model development, numerical modelling, and model validation to improve our understanding of the long-term fate of geologically stored CO2.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'EMPOWERING a reduction in use of conventionally fueled vehicles using Positive Policy Measures.' in the context of a Horizon 2020 call.

assistant: **Objectives**

The main objective of EMPOWER is to substantially reduce the use of conventionally fueled vehicles (CFV) in cities by influencing the mobility behaviour of CFV drivers and users towards fundamental change. To achieve this objective EMPOWER will create a set of tools for industry, policy makers and employers. These will empower them beyond the lifespan of this project to understand, help choose and successfully implement ‘positive’ evidence-based and cost-effective policy interventions, based on new and innovative mobility services, and in the context of already existing infrastructure, policy and measures. EMPOWER will reduce the use of CFV by: shifting trips to other modes/other vehicle types, promoting sharing and self-organisation and reducing demand overall e.g. through remote access to services. Undesirable impacts from CFV use will be reduced by: shifting CFV use to outside peak times and diversions to avoid particular areas/routes. The research will be multidisciplinary and involve: social science research with the public, 4 living lab experiments and 7 City demonstrators which will be chosen through an open 'bidding' process. The EMPOWER concept will be used in practice by: City stakeholders being able (through a software tool) to choose positive policy options based on their expected impacts and deliver incentives and social network sharing schemes to individuals using software. The innovation outputs of EMPOWER include an EMPOWER Toolkit to support industry, policy makers and employers to understand, choose and implement positive policy interventions. The Toolkit includes: new mobility services to provide innovative positive policy measures, new evidence on behavioural responses and impacts from positive incentives, improved organisational models for successfu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Science, technology and research for ethical engagement translated in society' (2021-2027).

assistant: **Concept**

The present version of the project S.T.R.E.E.T.S. (Science, Technology, and Research for Ethical Engagement Translated into Society) 2024-2025 marks a significant shift from the previous proposal: the most evident change is the shift of our focus from the streets to the squares as the focal point for the initiatives. This transition, defined as ""S.T.R.E.E.T.S. to (the) square"", also represents an elevation to the next level of engagement and an enhancement of the results of the previous project. The objectives remain consistent, emphasizing in all the initiatives the promotion of scientific understanding, opposing to misinformation, engaging the public, fostering public participation, advocacy for ethical research, and promoting innovation and social development.The project will continue to engage the entire Campania region and southern Lazio, potentially encompassing approximately 10% of Italy's population.The collaboration among all the prominent public universities of the Campania region, the network of more than 26 CNR Institutes, private companies, and various new third parties is confirmed. This result gives an idea of the positive impact of the first two years of implementation.Furthermore, the project addresses key themes on Europe's developmental agenda notably through the EU Missions. A specific attention is dedicated to the relationship with schools: researchers will engage with teachers, educators and pupils on challenges related, for instance, to climate change, sustainable development, health. Schools' initiative will also promote gender balance, diversity and inclusiveness in science in terms of planned activities and researchers involved.In this dynamic, the transition to squares as a meeting point represents a dynamic response to the evolving needs of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'SILICON FRIENDLY MATERIALS AND DEVICE SOLUTIONS FOR MICROENERGY APPLICATIONS' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

This proposal selects a series of relevant examples of power microgeneration and storage (thermoelectric generators, vibrational harvesters and microstructrured batteries) and pushes them further into their development and performance maturity. With that goal in mind the emphasis is put on the materials themselves and their integration route into a technology able to bring the eventual solutions closer to an exploitable phase. For this reason we consider novel silicon technology compatible materials as our starting point. The combination of those materials with device-making silicon micro and nanotechnologies is especially well positioned to make breakthrough developments in the microdomain regarding energy harvesting and storage. This approach enables (a) nanostructuration of the materials themselves, (b) dense device architectures by means of 3D high aspect ratio microstructures -which increase the resulting energy density, and (c) open the path for miniaturized complete systems through the compact assembly of the different elements involved (e.g. harvesters, batteries, power control electronics, devices to be powered) by means of hybrid or monolithic integration strategies. Wafer level processes will be favored to assure an easier transferability of the results to a fabrication stage. The high density architectures and system manufacturability provided by silicon micro and nanotechnologies endorse the use of silicon friendly materials even when their intrinsic properties may lag behind other technologically exotic material alternatives. Two application scenarios, engine/machinery fault prevention and tire pressure monitoring systems, relying on self-powered wireless sensor networks, have been chosen as frame of reference for our microenergy developments since they of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Children and Transnational Popular Print, 1700-1900' in the context of a Horizon 2020 call.

assistant: **Objectives**

Both popular and children’s literature have increasingly been understood as important elements of the pre-modern history of print. Exciting research is being undertaken in both fields. Yet systematic research on the crossover between these two forms of cultural production has not been undertaken. The extent, diversity and significance of children’s popular print remains largely unknown.CaTPoP will be the first project to methodically examine European children’s popular print, 1700-1900. An ambitious programme of fieldwork will provide the first overview of cheap, ephemeral print that was either produced specifically for children and young people, or that was used predominantly by them. The aim is to establish the extent to which popular print reached young people, and to give a full account of the different forms that were produced with children as a target audience. These will include educational books (eg. ABCs, almanacs, catechisms...), and more imaginative, and attractively illustrated works, including penny prints, ballads, chapbooks and romances. Despite linguistic, cultural and confessional differences, it is clear that some formats and titles appeared across Europe, and CaTPoP will take a transnational approach, tracing geographical (and temporal) continuities, and fractures. The aim is to assess whether a shared print culture existed for children across Europe. CaTPoP will not only advance scholarly understandings (print history; children’s literature), but will support the curation of cultural heritage. Secondments in different countries and sectors (a museum, a library, a university) will raise awareness and expertise among professionals, and support the communication of findings to a general audience, both online and through events and a touring exhibition.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Molecular Imaging of Brain Pathophysiology' in the context of a Seventh Framework call.

assistant: **Objectives**

BRAINPATH aims to build upon current developments in molecular imaging by creating an academic-industrial training and mobility network for the next revolution of imaging technology. Molecular in vivo imaging is a fertile area which combines expertise, state-of-art equipment and many disciplines and inter-sector work environments. Our goal is to better understand brain diseases and develop new preclinical imaging strategies. We believe optical imaging in particular represents a technology that has the potential to exploit further our knowledge in this area. Our main objective is to train a new generation of medical imaging scientists who, within the next 10-15 years, will bring optical brain imaging to the clinic. Indeed, it is envisaged that in the future optical imaging will be implemented as the fourth clinical modality in conjunction with the three already established clinical imaging techniques of Magnetic Resonance Imaging (MRI), X-ray Computed Tomography (CT) and Positron Emission Tomography (PET). Molecular in vivo neuro-imaging is rather underdeveloped, with its challenges specific to working on the brain, compared with other organs. Optical imaging can potentially play an important role in the multimodal orchestra together with MRI, PET and CT. Light can be used to measure functional aspects of the brain by either intrinsic monitoring of physiological changes, e.g. fluorescence, absorption, or by external contrast such as the use of fluorescence probes. Importantly, optical imaging is generally non-invasive and the equipment needed for such measurements are of low cost. A final unmet need is to integrate the different imaging modalities so that complementary information can be obtained from each modality. BRAINPATH will address this need and provide novel oppo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Three-Dimensional Sensory and Motor Space'.

assistant: **Concept**

Over the last years there have been more and more hints that the perception of motor actions might be supported by mechanisms that are very similar to those in control of these actions. This would make sence as both the perceptual and the control tasks share a large part of their computational problems.This series of meetings concerns the progress in the field of spatial coding, especially as it refers to our sense of motion and orientation, and as it leads to specific voluntary or reflex motor actions. We live in a three- dimensional world. Sensory inputs define our position in space and that of objects. Motor output is used for self- motion as well as for manipulation of objects. We experience one unique sensory space, which requires the fusion of visual, acoustic, somatosensory, vestibular, and other inputs. This is computationally a highly non- rivial process, as the sensory systems utilise different coding formats and co-ordinate frames.The first meeting will address the role of the cortex and the cerebellum in the generation of eye movements. Eye movements have been studied extensively as a model for sensory-motor transformations, because they are relatively simple movements, e.g. pure rotations, with a constant mass, and without intervening obstacles. The primary pathways for the generation of eye movements are within the brainstem and the midbrain. However, the role of cortical and cerebellar areas in the control of eye movements has recently received increasing attention. Their role in the plasticity and performance of eye movement generation is currently investigated at behavioural, electrophysiological and molecular level. The second meeting will focus on the computational mechanisms and strategies that allow us to generate and perceive movement and action in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Drugging the Undruggable: Discovery of Protein-Protein Interaction Modulators Using Diversity-Oriented Synthesis'.

assistant: **Objectives**

This proposal aims to exploit diversity-oriented synthesis in order to lay the scientific and technological foundations for the development of enzyme inhibition by protein-protein interaction (PPI) modulation as a tool for chemical biology and molecular therapeutics. We will deploy diversity-oriented synthesis lead discovery to explore concepts for PPI modulation in important enzyme families. This work will yield new chemical entities with a spectrum of properties directed against candidate macromolecular interactions important in the regulation of enzymes that mediate key biological pathways. The proposed work has the potential to transform current approaches to drug discovery, and to radically extend the repertoire of tools available for chemical biology. It will help to address the problem of identifying small-molecule inhibitors of PPIs, widely accepted to be of major fundamental and practical significance to biomedical science.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'NOVEL GRAM-NEGATIVE ANTIBIOTIC NOW' (2014-2020).

assistant: **Innovation**

AntiMicrobial Resistance (AMR) is a global and serious threat to human health. Gram-negative bacteria are widely regarded as the culprit representing one of the gravest dangers. Indeed, there is a dearth of new agents able to address AMR in Gram-negative bacteria, especially compounds with novel modes of action. Finding and developing such compounds represents a huge scientific challenge, one that requires the collaboration of stakeholders bringing many different kinds of expertise. The world is coming together to tackle this issue and public-private partnerships represent an attractive way to hasten the pace and increase the probability of successfully identifying and developing novel antibiotics. Under the global umbrella of the AMR Accelerator, the Gram-Negative Antibacterials-NOW (GNA NOW) consortium pledges to a 6-years commitment to bring together key European academic and private experts in antibiotic discovery and development in order to support and manage a portfolio of novel mode of action drugs against Gram-negative bacteria. Starting with three initial compounds/series, dedicated project teams will work together to define and execute the most efficient project plans. The consortium will put in place robust governance and management structures to ensure that the most promising compounds are pursued diligently. Ultimately, the goal of GNA NOW is to progress one compound through completion of phase I studies plus one compound reaching Investigational New Drug (IND) stage and/or up to two compounds reaching clinical development candidate stage.


**Keywords:** Gram-Negative Antibiotics, clinical development candidates
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Hydrothermal fluxes and biological production in the Aegean'.

assistant: **Concept**

Overall objectives To assess the effect of hydrothermalism on the chemistry, production and biodiversity of the oligotrophic Sea of Crete. Specific objectives 1. To determine the extent of submarine venting, measure bacterial production and export, quantify geochemical fluxe and their modification by bacterial growth. Establish periodicity of venting, the role of episodic events due to storms and seismicity. 2. Measure the effects of naturally occurring excess nutrients anc CO2 on the photosynthetic rate of phytoplankton, benthic diatoms and cyanobacteria and on chemosynthesis by sulphur-oxidising bacteria. 3. Compare the diversity of bacteria and epifauna in venting and nonventing areas, estimate the importance of chemosynthesis compared wit photosynthesis in the food web. 4. To isolate, identify and characterise hyperthomophiles and halophiles with bioproduct potential. State of the Art Hydrothermal areas around Milos were examined as' part of previous MAST projects on production in areas of high sulphide, and methane concentrations. These studies showed that 35 km of seabed around this one island were hydrothermally active. Free CO2 flux was 1-4% of the global mid-ocean ridge flux. Areas of seabed were influenced by hydrothermal brine, of similar composition to that in the reservoir 1 km below. Mats of sulphur-oxidising bacteria, >lOOm across, overlay the seeps. Bacterial H2S oxidation lowered the pH to 2 and released high concentrations of phosphate. Additional phosphate, ammonia, silicate, and other nutrients were released by the venting of hydrothermal fluids and gases. Episodic events were noted, including earthquakes, white smoker activity and release of brines resulting in a bottom-hugging, submarine 'fog'. We propose to study the processess controlling fluxes