RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Integration of Innovative Ice Protection Systems' under Horizon 2020.

assistant: **Concept**

This proposal fits within the framework of aircraft effectiveness constant improvement by reducing fuel and power consumptions. Its ultimate goal is to economically remove ice accreting on aircraft structure critical parts and thus increase reliability and mass saving on the global function. By comparison with the present existing solutions which are based on active pneumatic and electro-thermal means the targeted solutions will enable electrical power consumption, cost and mass reductions and ease the overall integration process.The subject of this proposal is to integrate and test two innovative ice protection systems in aircraft structures. The first system is based on two-phase heat transport and will be tested in a turboprop metallic air intake. The second system is based on electromagnetic induction and will be tested on a wing fixed leading edge and on a flap leading edge.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Virtual Reality Intervention for Stroke Rehabilitation' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Stroke has been recognized by the Israeli Health-Care policy planners as a top priority disease.  Individuals who have sustained a stroke constitute a large population with significant needs for rehabilitation.  The most common symptom following stroke is paresis or paralysis to half of the body, contralateral to the side of brain lesion. These individuals experience difficulties performing basic activities of daily life such as dressing and walking, in addition to instrumental activities of daily life such as shopping and cooking. Participation in regular physical activity is strongly recommended for individuals with stroke to maintain their functional level and prevent secondary conditions and a recurrent stroke. However, recent findings suggest that people with stroke do not perform enough physical activity.Virtual Reality (VR) enables the interaction with virtual objects in virtual environments which encourages movement and motivates the participant. The use of VR for rehabilitation has been reported to have potential for individuals with stroke.The aim of this proposed study is to assess the effectiveness of VR therapy to promote the participation in daily physical activity of individuals with stroke. A Randomized Controlled Trial (RCT) comparing VR therapy to traditional therapy will be applied for Step 1 (Community) and Step 2 (Home). Eligible participants will be randomly allocated to the experimental or the control group. Blind assessors will assess their ability pre and post a 3-month intervention and at 3-month follow-up. Novel instrumentation of VR systems and video-game consoles will be applied for the intervention of the experimental group and accelerometers (that measure the intensity and duration of movement) will be utilized for assessing ‘free-living’
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Hybrid Innovative Boundary Operators for Noise Treatment Evolution: application to duct acoustics' to be submitted under Horizon Europe.

assistant: **Abstract**

Aircraft noise has huge health and economic impacts, and the EU targets 65% of noise reduction by 2050. Meanwhile, restrictions in fuel consumption led to the Ultra-High-Bypass-Ratio turbofans, whose low-frequency noise signature challenges the scientific community. HiBONTE takes up this challenge, by designing innovative boundary noise control combining the most advanced know-hows on active and passive approaches. HiBONTE is the natural evolution of SmartAnswer MSCA-ITN (ESR12 task) and SALUTE H2020, both directed by the Ecole Centrale de Lyon (ECL), and the national project DAMA directed by the Università degli Studi di Napoli (UNINA). In ECL, an acoustic liner made of Electroacoustic Resonators (ERs) has been validated against turbofan noise. However, while efficient and tunable at low frequencies, high-frequencies are prevented by stability issues. Meanwhile, in UNINA, several passive concepts have been investigated, arriving at the conclusion that multistructured acoustic metamaterials (AM) hybridizing different noise control concepts, can improve global performances. However, AM, as all passive approaches, cannot escape the integral constraint requiring larger thickness at low frequencies. The need of hybridizing ERs and AM for broadband and tunable noise control, is evident, and times are mature to face this unprecedented challenge. HiBONTE will conceive an innovative boundary operator to be synthesized, for the first time, by a hybrid liner, which will be tested on highly representative testbenches in UNINA and ECL. Training activities will support each stage, and a unique multimodal flow-duct facility will be created in UNINA. The outcomes of HiBONTE are expected to be exploited by industrial stakeholders of both aircraft engines and Heating and Ventilation Air
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Interfacial Phenomena at Atomic Resolution and Multiscale Properties of Novel III-V Semiconductors' (PARSEM).

assistant: **Innovation**

The ultimate goal of this project is to provide a profound knowledge on III-V semiconductor heterostructures-nanostructures. The project will lead to extensive comprehension of growth mechanisms, microstructures and interfacial phenomena, as well as of the interrelation of structural and physical properties in order to control the atomic level the synthesis, the growth, processing and properties of novel III-V semiconductors such as III-nitrideternary and quaternary alloys, InN, and â-dilute nitrideâ- alloys. Such materials are extremely promising for the realization of devices for optoelectronic applications in UV to near IR wavelengths (e.g. light emittingdiodes, laser diodes, UV detectors), and high temperature, high frequency and power electronics like highelectron mobility transistors.In particular, quantum confinement of carriers in quantum wells and dots is anticipated to yield high performance for example by increasing the radiation efficiency of optoelectronic devices. The collaboration in this network of leading European experts in fields ranging from reactor design to electronic properties will revolutionize research in the field. An important objective is a contribution to the advancement and defragmentation of competitive European research in materials science and technology for device applications.The consortium combines the innovative multi-scale theoretical analysis of structures and properties with experimental characterisation by a unique collection of state-of-the-art techniques. The most important outcome from this multidisciplinary research effort is that a number of young researchers will be trained under expert supervision. Through mobility among the partners and a series of activities such as workshops and e-learning, they will become capable to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Online and automated E. coli monitoring for 100% safe drinking water' in the context of a Horizon 2020 call.

assistant: **Objectives**

Drinking water is the most essential resource for life. Access to safe drinking water can prevent disease outbreaks, and lower diarrheal and other disease burdens. According to the World Health Organisation around 330,000 cases of water-related disease such as E. coli are reported yearly in Europe. Just in 2016, 6,378 confirmed cases of Shiga toxin‐producing Escherichia coli infections were reported in the EU. Symptoms include diarrhoea, vomiting, stomach pains, nausea, headache, and fever. With the current technologies it can take two or more days to identify infectious risks in drinking water and by then the affected water is likely to have been consumed.ColiSense will bring to industrial production stage a quick (60 min), inexpensive (€1 per analysis) and accurate analyzer capable of detecting and quantifying E. coli cells in drinking water below the regulation threshold limits (1 cell per /100ml). ColiSense can be applied in a wide variety of industries, including the ones with the highest quality water demands in Europe (e.g. waterworks, food and beverage, pharma, cosmetic, etc.), and reach very high levels of efficiency. Our solution makes monitoring low-cost and easy to use with an enabled cloud dashboard (for remote monitoring) and analytic tools. The ultimate goal of ColiSense is to eliminate the large problem of E. coli contaminated drinking water distribution in EU (preventing people becoming sick by preventing them from drinking contaminated water).bNovate Technologies AG (bNovate) is a company that offers solutions to waterworks and food and beverage industries for automated monitoring of microbiological parameters and fast detection of bacterial contaminations in water. The bNovate staff is composed of experts and professionals who have extensive knowledge
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Deciphering RAdio NOn-thermal Emission on the Largest scales', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

This proposal aims to understand  the origin of the radio emission detected in the most massive objects in our Universe: galaxy clusters.The extreme physical conditions in the intra-cluster medium of galaxy clusters are beyond anything achievable in any laboratory on Earth. The space in between the galaxies is filled with an extremely hot and diluted gas that hosts the largest-scale magnetic fields known so far. A big challenge of modern astrophysics is understanding the origin of radio emission spread over huge swathes in some clusters. This emission is a mystery because it requires relativistic electrons moving around magnetic field lines, but both the origin of the magnetic fields and of the electrons are unknown. Absolutely fundamental to the understanding of the radio emission are a detailed knowledge of the magnetic fields and of the energy spectrum of the emitting particles.We are stepping into a new era of observational astronomy, in which surveys will be conducted rather than single pointed observations. This survey era is changing our approach to observational data. It enables to perform all-sky studies but calls for numerical and technological efforts for the data handling.Taking advantage of the advent of new radio and X-ray facilities, such as LOFAR, the JVLA, ASKAP, and  eROSITA, this project wants to understand the origin of the radio emission, its evolution and its connections with the cluster dynamics.We have today the unprecedented opportunity to discover the physical processes at work in these unique environments, that link the micro-physical processes at work in galaxy clusters with the clusters' macro-physics. The proposed  study will address fundamental questions not restricted to the physics of galaxy clusters but having impact on several inter-co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Precision oncology of spatial immune escape mechanisms in ovarian cancer' to be submitted under Horizon Europe.

assistant: **Abstract**

Tumor progression is dependent on the ability of malignant cells to escape the recognition and attack by the host immune system. The development of more efficient cancer immunotherapies has been hampered by the perplexity of immune escape mechanisms. I hypothesize that tumor genetic drivers dictate the immune escape mechanisms, and that these mechanisms can be exploited to develop more effective immunotherapeutic strategies for patients with high-grade serous ovarian cancer (HGSC), the most common and lethal ovarian cancer.My group has developed an optimized algorithm based on homologous recombination (HR) DNA repair deficiency to enable clinically meaningful stratification of the complex HGSC genotypes. We will define the immunogenicity of the HGSC genotypes via profiling tumor somatic mutations and neoantigens, the cell-type specific gene expressions, and T/B cell receptor diversities using altogether >600 HGSC samples. Using a cutting-edge highly multiplexed technology and advanced image analysis, we will reveal the single-cell spatial landscapes of the tumor microenvironment in 200 immunogenetically-defined HGSCs. We will apply pioneering spatial analyses on the single-cell data and use artificial intelligence to uncover clinically relevant spatial biology of HGSCs. Via transcriptomic profiling of 384 spatial microregions, we will discover the detailed immune-escape mechanisms of the HGSC genotypes. For functional testing, we have developed a groundbreaking method to establish immune-competent patient-derived organoids (iPDOs), which faithfully recapitulate the patients' tumors. Using our high-throughput iPDO functional platform, we will test mechanism-specific immunotherapeutic approaches and capture the treatment responses at single-cell resolution. The discovery
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Partial reprogramming for hematopoietic system rejuvenation: Impact on systemic hallmarks of aging and health span', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Aging is a complex process, encompassing the decline numerous cell types and organs. In this regard, recent progress suggests that the hematopoietic system is particularly influential; as we age, hematopoietic stem cells (HSCs) preferentially differentiate toward the myeloid lineage, thus losing their ability to regenerate fully functional blood tissue. Furthermore, a decline in the effector capacity of immune cells accounts for insufficient immunosurveillance of senescent cells, leading to their accumulation throughout the body.From a therapeutic perspective, the hematopoietic system is particularly malleable to rejuvenating interventions. In recent years, strategies of epigenetic reprogramming achieved through the transient expression of the Yamanaka factors Oct4-Sox2-Klf4 (OSK) and the facultative expression of c-Myc -referred to as partial reprogramming- has progressively garnered attention for its potential application in regenerative medicine. Their capacity to transiently push fate-committed cells back to their developmental program and to remove epigenetic marks of damage enhances the capacity of tissues to regenerate after injury in several preclinical models. However, it is poorly understood whether single-organ partial reprogramming affects other tissues and health span, without risks for secondary transformation, undermining the translational potential for humans.Across the REJUVIMMUNE project, I leverage on these limitations to develop unique tools –mRNA therapeutics and partial reprogramming mimicking cocktails (PRMCs)– for targeting partial reprogramming on HSCs (Objective 1) and elucidate cell intrinsic and extrinsic effects of OSK-rejuvenation on blood cells -including immune cells- and systemic aging, respectively (Objective 2).In summary, the strategi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Evolution of plant-animal interactions: a comparison of mainland-island fleshy-fruits characteristics' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

The principal aim of the proposed study will be to know the micro and macro evolutionary role of frugivorous vertebrates species as potential selective agents promoting changes in the fleshy-fruit characteristics in a comparative context (island-mainland), rarely take into account in previous studies. Ecological conditions acting in each situation (basically related to species number and taxonomie composition) determine strong differences in the structure of the frugivorous network in each site. These well differentiated ecological situations would help us to clarify the evolutionary consequences of the change in the principal mutualistics agents (mammals, birds or lizards) acting in the seed dispersal process (aspect that present some controversy, possibly related with the magnitude and scale of the study). Besides, to include information about the phenotypic selection pattern exerted by frugivorous vertebrates in these well contrasted situations, this controversy could be clarified. The plant species and po pulations inhabiting the Mediterranean Basin and Canary Island offers us a ideal framework to test general hypothesis (micro and macroevolutionary) about the role of seed dispersers species in the evolution of some fruits traits allowing similitude (or dif ferences) in the patterns of phenotypic selection exerted by frugivorous species. Besides, to use this comparative context, we gain in advantage because will be possible to study determined couples of plant species characterized by differences in the degre e and magnitude of the frugivore communities. This mean, plant species groups (or populations) without any substantial differences in the frugivorous guild in both places, others comparisons where the endemic laurel pigeons inhabiting the Canary Islands ac ts a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Adapting the feed, the animal and the feeding techniques to improve the efficiency and sustainability of monogastric livestock production systems' (Feed-a-Gene), addressing dissemination and exploitation.

assistant: **Impact**

Feed-a-Gene aims to better adapt different components of monogastric livestock production systems (i.e., pigs, poultry and rabbits) to improve the overall efficiency and to reduce the environmental impact. This involves the development of new and alternative feed resources and feed technologies, the identification and selection of robust animals that are better adapted to fluctuating conditions, and the development of feeding techniques that allow optimizing the potential of the feed and the animal.To reach this overall objective, the project will:- Develop new and alternative feeds and feed technologies to make better use of local feed resources, green biomass and by-products of the food and biofuel industry.- Develop methods for the real-time characterization of the nutritional value of feeds to better use and adapt diets to animal requirements.- Develop new traits of feed efficiency and robustness allowing identification of individual variability to select animals that are more adapted to changes in feed and environmental conditions.- Develop biological models of livestock functioning to better understand and predict nutrient and energy utilization of animals along their productive trajectory.- Develop new management systems for precision feeding and precision farming combining data and knowledge from the feed, the animal, and the environment using innovative monitoring systems, feeders, and decision support tools.- Evaluate the overall sustainability of new management systems developed by the project.- Demonstrate the innovative technologies developed by the project in collaboration with partners from the feed industry, breeding companies, equipment manufacturers, and farmers’ organisations to promote the practical implementation of project results.- Disseminate new
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Pressurisation of Ip-sofc technology for second generation hybrid application - target action A' (PIP-SOFC) under Fifth Framework.

assistant: **Objectives**

In the course of Framework 5, the European Commission has undertaken the major projects MF-SOFC and IM-SOFC-GT to develop key technology for SOFC stacks and SOFC/GT hybrids respectively. This project aims to build further on these initiatives and extend MF-SOFC technology to operation on hydrocarbon fuels (principally natural gas) within pressurised hybrid configurations. Advances in stack and system modelling achieved in part within IM-SOFC-GT will underpin this work. It is intended that reduced dimension support tubes and low cost high lateral conductivity current collector materials will be provided by a US DOE funded SECA project in return for this project making available 10kW stack blocks.The project aims to:- Develop 10 kW stack building blocks with integral internal reforming- Demonstrate operation of the 10kW block at pressure with hydrocarbon fuel representative of operation on natural gas