RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'The cap reform, set-aside and the arable crops sector in italy: an integrated evaluation approach' (1998-2002).

assistant: **Innovation**

The project is planned to start in October 2001. M1 - December 2001. Completion of the database. First mapping of Italian regions through MSA.M2 - March 2002. Definition and calibration of the PMP models. M3 - July 2002. Projections and simulations through the PMP models based on territorial farm aggregation. Second passage through the MSA approach and mapping. Convergence analysis on agricultural incomes and marginal prices of land. M4 - September 2002. Final results and analysis.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Quantifying the formation and evolution of the Archaean lithospheric mantle' to be submitted under Horizon Europe.

assistant: **Abstract**

The formation of the Archean lithosphere was a key event in Earth history, resulting in the construction of the first continents, or cratons. The lithosphere formed by extensive mantle melting, however, there are conflicting models for the environment in which melting took place. Efforts to understand the formation of the cratonic lithosphere are hampered by a lack of quantitative information on the depth of mantle melting and the original thickness of the Archean lithosphere. Exsolved orthopyroxenes within peridotite xenoliths and silicate inclusions in diamond hold the key to constraining these critical parameters. We will reconstruct the original compositions of an extensive collection of exsolved orthopyroxenes and use our recently published thermodynamic model to calculate their formation pressures and temperatures. This innovative approach will reveal the depth extent of Archean melting. We will provide the first constraints on the vertical extent of the lithosphere in the Archean using geothermal gradients calculated from dated diamond inclusions. To achieve this, we will perform cutting edge laser ablation U-Pb dating of garnet inclusions, this challenging application has yielded promising results for xenolithic garnet. Observations will be complemented by new experiments using fertile, depleted and silica-enriched compositions, coupled with with thermodynamic modelling, which will lead to a better understanding of phase relations during peridotite melting. The origin and significance of silica enrichment is poorly understood. We will conduct melt-rock reaction experiments to test the hypothesis that silica addition occurred via interaction with ascending komatiite melt. We will thus address several fundamental issues: the depth of Archean mantle melting; the or
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Experience-dependent modifications of developing neural circuits and animal behaviours' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

During development, neuronal connectivity is initially established by genetically determined intrinsic factors, e.g. molecular cues and spontaneous activity, generating networks according to a ""best guess"" strategy.  However, with the appearance of sensory organs, external inputs will refine these connections, allowing adaptation to the environment. In the Xenopus developing visual system, repetitive moving visual stimuli induce long lasting changes in the direction-sensitivity of some tectal neurons, apparently via modification of synaptic strength. However, it is still unknown how this synaptic plasticity contributes to the refinement of neural circuits for precise information processing and adjustment of animal’s behaviours.  Using a multidisciplinary approach combining cutting-edge genetic engineering methods to monitor and manipulate activity of specific neurons or entire circuits, development of novel mathematical and computational methods and kinematic analyses of motor behaviours, I will investigate how sensory visual experience may affect the activity and interaction of the optic tectum neuronal circuit and motor behaviour.  These experiments will contribute to our understanding of the role of sensory experience in shaping the development of neural circuits and animal behaviour. They will also shed light into the mechanisms by which the nervous system self wires, adapts, and learns.  The study of these mechanisms might contribute to the design of new therapeutic treatments for developmental disorders associated with impaired nerve connections.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Structure/function analysis of LRR proteins and their ligands in plant pathogen interactions and engineered resistance' (1994-1998).

assistant: **Concept**

This consortium will carry out structure/function analysis of proteins that play a role, or that may play a role, in plant-pathogen interactions. Proteins carrying leucine-rich repeats (LRRs) and their interaction with other proteins, will be of primary interest. Our main scientific objective is to advance our understanding of plant-pathogen interactions at the level of structural biology and protein/protein interaction. In collaboration with an industrial partner (MOGEN), our applied research objective is to exploit Cf-Avr genetic interactions to deliver durable resistance to potato late blight caused by Phytophthora infestans. Longer term, our investigations will open up the useful possibility of engineering synthetic resistance genes that recognize defined pathogen-derived ligands. We will study three classes of LRR proteins and (where appropriate) their interaction with molecules derived from fungal plant pathogens. (i) Proteins encoded by the tomato resistance genes Cf-4 and Cf-9, which carry 26 or 28 LRRs respectively, and their interaction with the AVR peptides AVR4 and AVR9, produced by the fungal pathogen Cladosporium fulvum. The Cf-gene products enable specific recognition of the AVR products and upon recognition, activate the defence response. We will carry out biochemical and structural analysis of the Cf proteins, and their potential AVR ligands. We will investigate whether the genetic interaction between Cf and Avr genes involves direct physical interaction of their gene products. Analysis of various mutant AVR peptides will help unravel the molecular and physical basis of ligand/receptor interaction. (ii) Plant polygalacturonase inhibiting proteins (PGIPs), which carry 10 LRRs and inhibit fungal polygalacturonases (PGs). PGs have important functions durin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Aero-acoustical and thermo-acoustical coupling in energy processes' (AETHER) under Sixth Framework.

assistant: **Objectives**

The objective of AETHER is the development of a unique and highly qualified training and research environment for fellows motivated to develop their careers into sustainable energy production. The network is composed of universities, research centres and industry partners, covering 8 countries of the ERA, all linked through their excellence in energy processes. The network is multi-sectorial, as three sectors of activity are targeted: gas turbines, combustion systems in manufacturing industry, and domestic/district heating systems.These three sectors constitute key domains in the energy production and consumption landscape, and are linked by a common technological issue: combustion systems are prone to instabilities that are not only detrimental to their performance and lifetime, but also lead to increased emissions of pollutant species, some of which are strong contributors to the greenhouse effect.The research aims at a better control of aero-acoustical and thermo-acoustical coupling issues. State-of-the-art numerical, experimental and modelling techniques will be developed, upgraded and applied under the guidance of top-rank researchers. A particularly innovative aspect of the proposed research regards the thermo-acoustical behaviour of biofuels, as at present little knowledge exists on that topic.Todays engineering challenges are multidisciplinary by nature, and the network will provide a multidisciplinary training through research, a structured course program and well-scheduled secondments. Personal coaching and distributed workshops will constitute the backbone of the training, transfer of knowledge and management activities.The training program will take advantage of the particular multi-sectorial structure of this network. The fellows will be granted a broad kno
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Visualising age- and cataract-related changed within cell membranes of human eye lens using molecular rotors' (Cata-rotors), addressing dissemination and exploitation.

assistant: **Impact**

The lens of a mammalian eye is a unique tissue, which maintains high transparency during an individual lifespan, yet has no protein and lipid turnover. Thus, the eye lens is considered as one of ideal models of human aging. With age the proteins and lipids of the lens accumulate numerous post-translational modifications, leading to defects in the cell membrane structure and, therefore, to impairments of metabolite transport. The retarding of the metabolite exchange predisposes the lens nucleus to oxidative stress – a key factor in the formation of cataracts. Therefore, a study of the normal functioning of the lens, as well as age- and cataract-related changes in metabolite transport through the lens cells may shed light on the general mechanism of the lens aging and cataractogenesis. The present project is aimed at investigating and directly quantifying age- and cataract-related changes in the properties of cell membranes of the human eye lens by Fluorescence Lifetime Imaging Microscopy (FLIM), employing fluorescent viscosity-sensitive probes termed ‘molecular rotors’. We envisage that the results obtained will show the distribution of viscosity within membranes of fibre cells and will allow to directly visualise how the age and the early stages of cataract influence on fluidity of these lipid bilayers, which are of vital importance in maintaining the clarity of our eye lens and our vision. Analysis of age-related changes in the structure of membrane proteins and experiments with animal eye lenses subjected to photo-oxidation and chemical oxidation will provide additional information on the mechanisms of age- and cataract-related changes in viscosity within lens fibre cell membranes. Overall, this project addresses issues of fundamental importance in biophysics, as well
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'ANotec-COmoti Rotorcraft Acoustics initiative for preliminary acoustic flight tests for the tuning of simplified rotorcraft noise models' (ANCORA) targeting Seventh Framework.

assistant: **Abstract**

One of the objectives of GRC5 is to implement a tool for the minimisation of noise impact on the ground, capable of being executed on-board “on-the-fly”, providing flight directives to the FMS of the helicopter. To this end reliable and fast noise predictions will have to be made, based on actual flight conditions. The envisaged semi-emperical model to be used for this purpose requires information to be derived from experimental data.The main objective of  ANCORA is to determine the transfer function between the noise measured on-board the helicopter, close to the noise sources, and the noise received on the ground by a grid of microphones, during a flight test campaign.ANCORA will investigate the application of surface microphones on the helicopter fuselage and will subsequently use this knowledge for the flight test campaign.ANCORA will deliver a robust and reliable mobile noise measurement system, easily scalable and optimised for minimum deployment time and cost.During the test campaign a large number of steady-state conditions and manoeuvres will be flown over a grid consisting of 31 microphones.ANCORA will develop an advanced method for the determination of the transfer functions between on-board and ground microphonesAll results from the flight tests and data analysis (raw data, 1/3 octave spectra, transfer functions) will be made available through a data repository.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Large Area Solid State Intelligent Efficient luminaires' (LASSIE-FP7), addressing dissemination and exploitation.

assistant: **Impact**

According to a recent study, many solid-state lighting (SSL) products do not fulfill the claimed specifications and a deep market penetration of LED modules is at risk. The main problems are decreasing light intensity and varying light chromaticity due to aging and temperature, as well as poor uniformity of large-area luminaires and poor lighting quality. The main objective of the LASSIE-FP7 consortium is to implement large-area and low-cost intelligent SSL modules with high efficiency and high lighting quality, while assessing their environmental impact over the life cycle. LED-based point source luminaires have been already investigated, but market requirements for intelligent, large-area solid-state light sources have not been met yet. In order to achieve luminaires with high intensity, good uniformity and high color rendering performance, significant intelligence has to be added to the LEDs. By integrating light management structures combined with new color-changing coatings containing highly efficient and reliable organic fluorescent dyes with heat management solutions, LED chips and multispectral sensors for intelligent color-sensing feedback by means of an innovative R2R production technology compatible with flexible substrates, the LASSIE-FP7 consortium will achieve progresses beyond the state-of-the-art in terms of size (area and thickness), flexibility, efficiency, lighting quality, beam-shaping, lifetime, added intelligence, production and production/installation costs. Outcome of the project will be a unique integrated SSL module that will represent a break-through in the professional and architectural lighting sectors and an alternative to the OLED technology.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Rapid Identification of Respiratory Tract Infections' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Respiratory Tract Infections (RTIs) are caused by a variety of bacterial, viral, fungal and other pathogens. RTIs are major causes of morbidity and mortality in adults and children worldwide causing millions of deaths each year. RTIs affecting the lung parenchyma (pneumonia) can be classified into three main categories: Community Acquired Pneumonia (CAP); Hospital Acquired Pneumonia (HAP) which includes Ventilator Associated Pneumonia (VAP); and opportunistic pathogens causing pneumonia in immunosuppressed patients (Opportunistic RTIs or ORTIs). RTIs are difficult to diagnose accurately and current standard microbiological culture based tests are laborious and time consuming with a turnaround time to results > 30 hours. Thus, all ill patients presenting with CAP, HAP, VAP or ORTIs are initially treated empirically with antibiotics, without an accurate identification of the causative microorganism and associated antibiotic susceptibility profile. This leads to inappropriate use of antibiotics, which can increase patient morbidity and mortality. Therefore, there is a great need for rapid molecular diagnostics tests capable of identifying a large range of microorganisms and antibiotic resistances rapidly and accurately so that appropriate therapy can be instituted on first consultation. Accurate pathogen identification and resistance profiling is also important for the epidemiological surveillance of pneumonia. The aims of the RiD-RTI project are (through a unique partnership of SMEs, universities and hospitals from 4 countries) to develop and evaluate three diagnostics products for the rapid diagnosis of CAP, HAP/VAP and ORTIs, based on a novel “sample-in, answer-out” diagnostic platform. The diagnostics products will be designed to be ‘near patient’, reliable, cost-effec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Multi-criteria assessment and optimization of geothermal heat pump systems' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The use of shallow geothermal energy is continuously rising and, in particular, the application of vertical ground source heat pump (GHP) systems is expanding. Such applications are attractive for their potential to reduce greenhouse gas emissions while offering economic advantages in comparison to fossil-fuel based space-heating. Single GHP systems are well established for small residencies. Growing interest is directed towards bigger scale applications with galleries of multiple GHPs, for which much less experience exists and little research on appropriate planning and design is available. During the proposed reintegration phase at the Engineering Geology Institute at the ETH Zurich, a three-year project is planned that develops an innovative computer-based assessment/optimization methodology. It benefits from the previous Marie Curie Intra-European Fellowship by setting up a state-of-the-art full environmental assessment procedure according to Life Cycle Assessment (LCA) standards. Further, it contrasts the LCA-based evaluation of GHP systems with respect to different impact categories with technico-economic criteria. The different criteria will be quantified in a flexible manner for a broad range of multiple GHP configurations. By implementation of the assessment procedures into a mathematical optimization problem, optimal GHP gallery design and operation will be computed. The methodology will allow categorising sensitive status, design and control parameters with respect to various, potentially contradicting criteria. In the final phase, demonstration to two prominent real cases is planned in order to show applicability and to examine the potential of the new approach to improve current multiple GHP system planning practice.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Contribution of Compact Neighbourhoods to Social Sustainability'.

assistant: **Concept**

This research investigates how compact urban form can promote the social sustainability of intermediate neighbourhood areas in the major European cities which face socio-cultural challenges such as social segregation and cultural disintegration. Combining the three critical concepts of ‘neighbourhood development’, ‘compact urban form’, and ‘social sustainability’, the study sheds light on their interconnectivity, and thus provides practical recommendations to promote social sustainability for the neighbourhood level. Despite the fact that these concepts have been incorporated into European urban development policy, a remarkable gap in knowledge is observable: interdisciplinary comparative empirical surveys are needed to investigate their multifaceted aspects and discover the commonalities and differences between different contexts.The two cases of London and Berlin are considered as the case studies, due to the progressive initiatives they have developed with regard to the above-mentioned concepts. Employing a combined methodology including literature review, on-site investigations, interviews, and questionnaires, this research consists of four main stages. After studying the state of the art of the central questions, four neighbourhoods (two each) in intermediate urban areas of the case studies will be selected as field study areas (FSAs). A goal-oriented, multidisciplinary quantitative methodology will measure different indicators of ‘urban form’ and ‘social sustainability’ using progressive tools and indicator-indices (questionnaires). The findings will be scored and evaluated through statistical techniques to explore the interconnectivity of the indicators and their strengths and weaknesses. Ultimately, an Urban Form Enhancement Index will be provided for each FSA w