RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Behavioural Individuality in C. elegans' under Horizon 2020.

assistant: **Concept**

Animal behaviour is shaped by genetic traits, memories of past experiences and current internal states. Even in isogenic animal populations in a controlled environment, individual behaviour can be found. I obtained evidence that unexpectedly, the behaviour of adult C. elegans nematodes is influenced by the age of their mother. Progeny from young mothers explore less and dwell more in the same spot. I will exploit the model to characterise how the physiology of one generation determines the behaviour of the next generation. Second, I will determine additional environmental factors that imprint on C. elegans during development and thus modulate behaviour later in life. To examine the mechanism of maternal-age induced and environmentally induced behavioural variation, I will combine innovative genetic and pharmacological tools with state-of-the animal tracking and quantitative behavioural data analysis. I aim to determine the molecules and cells that sense and transmit the signals during development, and characterise the changes in neuronal wiring affecting behaviour in adult animals. Funding for this project will allow me to describe how 1) transgenerational effects such as maternal age and 2) environmental stimuli modulate behaviour later in life, in an amenable model organism such as C. elegans. Both parts of the project will partially overlap in time to complete the action within a 2-year time frame. As components of the nervous system are largely conserved between the nematodes and mammals, findings are likely to be extrapolated to higher animals.


**Keywords:** Behaviour, Imprinting, C. elegans, Maternal Age, Environmental Stimuli
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Company metrics programme introduction : a quantitative approach to software process understanding and improvement' under Fourth Framework.

assistant: **Concept**

Due to the growing complexity of projects, improving software product quality, product performance, and development team productivity has become a primary priority for almost every organisation. This experiment is a simple approach to improving software quality and productivity by measurement of the product and process. The objective is to quantify the costs and benefits of each major project activity.THE EXPERIMENTThe achievement of the objective above requires the following key actions for improving our products and development process:- to establish a minimum basic set of process measurements to identify the quality and cost parameters of each process step (Process measurement)- to establish a process database with the resources to manage and maintain it (Process database)- to provide sufficient process resources to analyse this data and advice project members on the data's meaning and use (Process analysis)- to assess the relative quality of each product and inform management where quality targets are not being met (Product quality).The goal is to start a company metrics programme in order to drive a software process understanding and improvement. One of the key assets of the improvement program is the metrics initiative. The main goals of the metrics program are:- to provide the quantitative information essential to identify opportunities for improvement;- to verify the advantages of the implemented changes to the development process.The adopted metrication approach is the AMI method (Assess, Analyse, Metricate, Improve). The assessment is the key step:- to understand the status of the company's current software practice and to show strengths and weaknesses- to identify key areas for process and product improvement- to facilitate the initiation of improvement actio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Drug eDesign: Building the next generation of software solutions for drug design'.

assistant: **Objectives**

Computer simulations are taking over in design processes. Nevertheless, complex projects will largely benefit from humanintuition and team-work. We aim to combine computer and human power into the next generation of fully interactivecomputational tools for drug design. The goal of eDRUG is prove the potential of this novel computational solution in thecurrent pipeline of drug development and the prospective interest that it will raise in the pharmaceutical industry.We aim at merging human knowledge with state of the art affordable computational resources to create an interactive and(capable of) intuition-guided software solution. The idea seats on three technological pillars: 1) the PELE software allowingfast biophysical characterization of drug-target interactions, 2) advances in computational hardware providing morecomputational performance in reduced space, requiring lower power consumption and acquisition cost, and 3) bettergraphical devices allowing a richer and faster human(team) data analysis and software interaction.The goal matches with increasing and future needs from pharmaceutical companies to improve rational drug design (inresponse to cell/virus mutations, personalized medicine, etc.). One worldwide leading pharmaceutical company, and a local biotech SME, will be counseling the developing team and testing the prototypes, to meet a product that fulfills industry expectations.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'GOTaM Cities - Geography Of Talents in Metropolitan Cities' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

In the context of a growing knowledge economy the competitiveness of global cities is crucially affected by their ability to nurture and attract talented workers. In this global race the European Union is lagging behind in comparison with the US and other Anglo-Saxon economies. The diffusion of anti-immigration sentiments is also worrisome because the recovery from the Great Recession of 2008 is far from being in sight for many EU regions while the access to a diverse set of skills via high skilled immigrants could boost the innovative sectors needed for economic growth. Therefore it is important to provide robust evidence on the economic effects of High Skilled Immigration (HSI) in order to justify policies for their attraction. GOTaM cities aims at understanding how talents are attracted to cities and how they impact on their innovative performance and prosperity. While building on existing literature the project will make several contributions by addressing some unexplored questions and empirical shortcomings: a. GOTaM will focus on HSI in different geographical contexts (i.e EU, US, China and Brazil): the existing evidence is biased towards the US which leaves a lack of understanding about HSI in other areas;b. It will use individual data and focus on city/region level effects: most empirical literature relies on aggregate data at country level; c. It will investigate the qualitative effects of migration: whether HIS enhances the technological and economic diversification of cities by bringing new knowledge to those places;d. It will build a unique comprehensive dataset (and related methodologies) on migrant inventors and scientists which will help the scholarly community and policy makers to carry out informed empirical analysis: the findings so far are disputed al
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Development of a 3D-map interface for touristinformation on mobile computers' (TELLMARIS) targeting Fifth Framework.

assistant: **Abstract**

TellMaris will focus on tourists and citizens on the move, and their need for tailor made tourism information using mobile terminals and an existing Destination Management System (database) as ambient intelligence environments. The scientific objective is to develop new data structures for representing interactive 3D maps on mobile terminals, combined with mobile location services. The end user objective, using boat tourists in the Baltic Sea Region as a case, is to improve the quality and the easiness of getting land based tourism information.Objectives:The main objective of TellMaris is to develop a generic 3D-map interface for access to tourist information on mobile terminals. To reach the objective of the project the following partial research objectives should be obtained:1. Understand the market preferences and the best solutions through market survey and benchmarking;2. Develop 3D data structure for geodatabase storage capable for storing terrain and city models coupled to geographical features relevant for tourism;3. Develop a 3D-map based local data structure for the mobile computer that is a subset of the geodata stored in the geodatabase;4. Develop necessary middleware technology for data communication and technology for effective network streaming of 3D terrain and city models;5. Develop technology for 3D rendering and visualisation of 3D map data on mobile;6. New means for interface interaction in 3D space;7. Carry out two demonstrations to get feedback on user friendliness.Work description:The innovative aspects of TellMaris are based on an integration of recent technological and scientific advances within telecommunication, geometric modelling, geospatial technology and computer graphics to provide better means for information retrieval on mobile terminal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a FP7 proposal on 'Reinforcing the international cooperation in FP7 FAFB strengthening the CIRCLE of Third Countries BIO NCPs'.

assistant: **Concept**

The main objective of BIO CIRCLE 2 is to foster the knowledge base about FP7 FAFB & the networking capacities of Third Country researchers in order to reinforce their participation in FP7 projects. 3 project goals are distinguished: 1.Disseminate information effectively to Third Country researchers; 2.Organise information days and training for Third Country researchers; 3.Provide Third Country researchers with efficient networking opportunities. 5 European plus 16 Third Country partners (International Cooperation Partner Countries ICPC and Industrialised Countries) will all be involved in the activities. Apart from Kazakhstan and Thailand all involved countries (and the African continent represented by FARA) have signed a bilateral S&T agreement with the EU. The expected impacts are supported by various activities: Enhanced awareness of the Third Country researchers on the FP7 FAFB: WP2 will develop the regional strategies for the Third Country partners. Increased Third Country researchers’ participation in EU projects: WP3 will organise at least 2 trainings for Third Country researchers at national and regional level, 3 trainings of Third Country BIO NCPs and the organisation of 1 Regional Event per World Region. Strengthened collaborations with Third Countries signatories of bilateral S&T agreements with the EU: WP4 will implement networking activities for Third Country researchers, including brokerage events and working visits of Third Country researchers to EU research institutes and vice versa. Finally WP5 on dissemination activities will increase the awareness of European researchers about the international cooperation in FP7 FAFB. The impact of the activities will be further maximised by: 1.involving other countries that are not partners through a regional approa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Dissecting the cellular mechanics of contact inhibition of locomotion'.

assistant: **Concept**

Our aim is to dissect the mechanisms of contact inhibition of locomotion (CIL), a process whereby migrating cells collide and repel each other, as it is now clear that CIL is pivotal to understanding embryogenesis and pathologies such as cancer. We have developed an in vivo model using Drosophila macrophages (hemocytes), along with novel analytical tools, to examine the contact inhibition response in cells during development.  We therefore have an unprecedented opportunity to address CIL in a genetically tractable organism within a physiologically relevant setting. This model has revealed that a precisely controlled CIL response is a significant driving force behind the acquisition of embryonic patterns, and recent data show that this precision requires a series of synchronized changes in cytoskeletal dynamics. Our central hypothesis is that key to this cellular ‘dance’ is mechanosensation of the collision, which integrates subsequent signaling mechanisms to choreograph the steps of the contact inhibition process. The first part of this proposal will elucidate the molecular mechanisms controlling CIL by exploiting our unique ability to live image and genetically dissect this process in Drosophila. We will also take an interdisciplinary approach to elucidate the mechanical aspects of the response, which will allow us to examine the feedback between signaling pathways and the physical forces of the CIL response. We will subsequently extend our detailed understanding of the CIL process, and our novel set of analytical tools, to mammalian cell types and model systems. This will allow us to develop new assays to directly probe the mechanics of CIL and begin to investigate the function of this underexplored process in other cell types. This in depth knowledge of the response
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Cardiovascular determinants of dementia' (1994-1998).

assistant: **Concept**

The general objective is to investigate the short-term and long-term association of cardio-vascular factors to dementia and cognitive impairment.The specific objectives are to:study geographic variation in white matter lesions and cognitive function.study the relation of cardio-vascular factors to white matter lesions, cognitive function, and dementia.study the relation of white matter lesions to cognitive function and dementia. Dementia is a highly prevalent disease affecting more than 5% of those 65 years and older and more than 30% of those 80 years and older. Few preventable risk factors for dementing diseases have been identified. Evidence from different studies suggests that cardio-vascular risk factors and atherosclerosis may contribute to dementing disease and cognitive impairment through brain lesions and atrophy. We propose a collaborative population-based study of: (1) the role of cardio-vascular factors in the occurrence of white matter lesions, cognitive impairment and dementia; (2) the role of white matter lesions in cognitive impairment and dementia. White matter areas of the brain are extremely vulnerable to vascular processes such as ischemia, hypoxia and haemorrhage. White matter lesions can be well measured with magnetic resonance imaging. The presence and severity of white matter lesions have been associated with stroke, peripheral artery disease, hypertension, and carotid artery disease. Furthermore, white matter lesions are present in demented patients as well as clinically normal subjects with cognitive impairment. This collaborative study will be based on two groups of population-based studies that differ by when the risk factors were measured relative to the measurement of brain changes, cognitive function and dementia. The first group initially
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Flexible querying of fuzzy and uncertain object-oriented database managementsystems - a case study' under Fourth Framework.

assistant: **Concept**

Research objectives and content This project concerns both the object-oriented model of databases (which is promised, in the near future, to be referred to as the standard for next generation databases) and the different theories of imprecision. The notion of imprecision can be introduced in a database at two main levels: 1) in the data description (classical approaches allowing only for precise values, the aim is then to extend data management to partially unknown data), 2) in the queries (imprecise or flexible queries which enable database users to express preferences inside elementary conditions and priority between conditions). Some fuzzy object-oriented database models have been defined recently and now work is going on, attempting to define a unifying framework which could encompass these different-models. At the host institution an object-oriented database model, called UFO, has been defined, which allows us to handle fuzziness and uncertainty in data. The mapping of this model onto a relational model has also been described. Training content (objective, benefit and expected impact) The study of appropriate querying techniques for fuzzy and uncertain object-oriented database management systems is the next step; which merely has been addressed by now. This project aims at designing a flexible query language for the fuzzy and uncertain database model UFO (extended if necessary). The applicant being already involved in flexible querying (in the relational model of data), this project gives him the possibility to extend his research and to train himself to object-oriented environment.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Institutions and Individuals in the Distribution of Welfare in Europe' under Seventh Framework.

assistant: **Concept**

The proposed project aims to develop a new approach in welfare state studies using new conceptualization and the state of the art statistical techniques. This fresh approach will be used to analyze the roles of four main welfare institutions—namely the state, the family, the market, and local actors in the distribution of welfare shaped by the intersections of age, class, gender, and race relations in Europe.In order to achieve this overall objective, the following three specific objectives will be important in this project. First, this project aims to develop a new approach in welfare state and social policy studies to understand the distribution of welfare that is shaped by the intersections of age, class, gender, and race relations. Second, by comparing different societies, it is aimed to analyze future social, economic, and demographic challenges to the welfare regimes particularly with reference social inequalities. Third, it aims to reassess welfare regime typology and examine the question of path dependency of welfare policies. The methodology to be used in analyzing the welfare of the old in the various regimes depends on quantitative and qualitative secondary data and previous studies on welfare states and social policies. Since this is a cross-national research, mostly comparative data on social policies, social welfare, and demographic indicators will be used from the EuroStat and other data resources which provide comparative data for researchers.