RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Home care and remote monitoring system for the population with special needs allowing expert advice to be generated ex situ based on the collected data.', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

Our goal is to enhance the effectiveness and efficiency of management of home care patients with chronic disease and facilitate overall control over the disease by introduction of a newly developed concept and technology. Introduced low cost, easy to use and simply understandable interactive monitoring will teach the patients how to regulate themselves. This will give the patient a sense of control and allow medical personnel to stay ahead of acute heart failure or other critical conditions. Doc@HOME will provide means for integrating the elderly and disabled into society by introducing remote care essentials quickly and effortlessly to those in need, reducing the overall cost of the patient care and will increase the life quality of the community with diverse health related predicaments. Furthermore, the concept foresees an intuitive work environment for the doctor and care provider establishment.DESCRIPTION OF WORKThe project is organized into five main phases, each of which ends with a specific milestone. An incremental approach is used for each phase allowing the research results to be exploited independently and the progress to be assessed prior to project completion. To some extent this will enable to reduce the research risks and minimize plan disruption. The presented phases have been defined carefully to build upon each other and to ensure that the research deliverables are fully adopted into the development activities. For the reasons of quality control a number of intermediate and minor milestones and process control variables are defined and will be continuously traced by Project Coordinator. For the case of deviation from the preset goals alternative strategies for process management have been defined. As a main goal a service configuration and provisioning
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Air Quality and Health' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Specific Objectives:1. Harmonisation and standardisation of air quality measurements (ERLAP sector) 1.1 Development of reference methods and measurement strategies in support to new directives and validation/standardisation of measurement methods for new pollutants in collaboration with CEN and ISO. 1.2 QA/QC programmes for a harmonised implementation of air quality directives. Particular emphasis on training of laboratories in EU and CC. Activity conducted trough networking with national air quality reference laboratories in the framework of AQUILA. 1.3 Validation and QA/QC of diffusive samplers for the assessment of air quality in urban, rural and forest areas, for indoor and personal exposure measurements. Activity conducted trough networking with air quality research laboratories and in the framework of CEN standardisation activities. 1.4 Provision of guidance to MS for the implementation of air quality directives. Particular emphasis on training of laboratories in CC and Balkan Countries. 1.5 Setting-up of Association of European Air Quality Reference Laboratories (AQUILA). Networking with national air quality reference laboratories. 1.6 Study on the development of certified low concentration reference materials for benzene, NO2, SO2, and CO in gas cylinders, and for benzene, SO2 and NO2 by diffusive samplers (CERMATAIR project). 1.7 Calibration of satellite data on formaldehyde as a tracer for photo-smog in the atmosphere. 1.8 Measurement of air pollutants deposition over different surfaces (agricultural and forest ecosystems). QA/QC protocols and harmonisation of methods of evaluation of environmental deposition in collaboration with UN/ECE in the frame of LRTAP Convention. Support to modelling and mapping of environmental deposition at European scale;2. Air qual
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Hardware Development of Wireless Sensor Network Nodes for Operation in Airborne Environment'.

assistant: **Concept**

Today, wired sensors are used for monitoring the condition of aircraft engines, structures, gear boxes, and so on. Wireless Sensor Network (WSN), i.e., smart sensors with radio interfaces, promise unprecedented operational benefits; such as, reduced airplane sensor wiring costs and weight as cabling is limited to specific scenarios and the flexibility to be deployed on-board aircraft without requiring a redesign of the data wiring layout. Such benefits are also important arguments for programs such as Green Regional Aircraft which aims at developing and installing sensors to continuously control accidental damage, environment effects, and consequently in service structural degradation, targeting a 9% reduction of the empty weight of the aircraft. To this end, AirWISE is developed in response to the requirements described in the Clean Sky call for proposals referenced under JTI-CS-2009-GRA-01-019 and named “Miniaturized Sensors”. AirWISE is focused on developing a generic hardware platform for airborne WSN nodes leveraging an existing low-power 2.4 GHz CSEM wireless module known as ZorgWave. The technical strategy is to evaluate, re-design and re-qualify the existing module to adapt it to the limitations and constraints imposed by operation in airborne environments in accordance with FAA regulations. The design and development of the WSN hardware will be performed by CSEM in accordance with the requirements described in the call for proposals. In order to fulfill these requirements, in particular those related to the aeronautics environment and regulations, CSEM will collaborate with RUAG Aerospace which will be working in this project as aeronautics advisors. RUAG Aerospace will also advise on the quality assurance of the project CSEM will bring to AirWISE its long trac
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Solving Conformal Field Theories with the Functional Bootstrap' under Horizon Europe.

assistant: **Concept**

Conformal Field Theories (CFTs) have a wide range of experimental and theoretical applications: describing classical andquantum critical phenomena, where they determine critical exponents; as low (or high) energy limits of ordinary quantumfield theories; and as theories of quantum gravity in disguise via the AdS/CFT correspondence.Unfortunately, most interesting CFTs are strongly interacting and difficult to analyse. On the one hand, perturbative andrenormalization group methods usually involve approximations that are hard to control and which require difficultresummations. On the other hand, numerical simulations of the underlying systems are difficult near the critical point and canaccess only a limited set of observables.The conformal bootstrap program is a new approach. It exploits basic consistency conditions which are encoded into aformidable set of bootstrap equations, to map out and determine the space of CFTs. A longstanding conjecture states thatthese equations actually provide a fully non-perturbative definition of CFTs. In this project we will develop a groundbreakingset of tools ? analytic extremal functionals ? to extract information from the bootstrap equations. This Functional Bootstraphas the potential to greatly deepen our understanding of CFTs as well as to determine incredibly precise bounds on thespace of theories. Our main goals are A) to fully develop the functional bootstrap for the simpler and mostly unexplored one-dimensional setting, relevant for critical systems such as spin models with long-range interactions and line defects inconformal gauge theories, leading to analytic insights and effective numerical solutions of these systems; and B) to establishfunctionals as the default technique for higher dimensional applications by developing the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Personalised Treatment For Cystic Fibrosis Patients With Ultra-rare CFTR Mutations (and beyond)' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

In our HIT-CF project, we aim to bring personalised disease modifying therapies to cystic fibrosis (CF) patients with ultra-rare CFTR mutations, who could otherwise never get access to such treatment. Once we have proven our unique concept, the CF community can easily extend our state-of-the-art methodology to all CF patients such that HIT-CF will impact the entire CF field. We will achieve our goals by means of a randomised, double-blind, placebo-controlled, repeated-crossover, three-armed platform trial with prospectively defined meta-analysis to evaluate efficacy at group and individual level. HIT-CF is designed to enable access to the most relevant global drug products, and each trial arm will test a drug product candidate (a single compound or a compound combination) from one of our pharmaceutical consortium partners. The patients will be assigned to the specific trial based on the effect of the drug product candidates on cultured intestinal miniature organs (termed organoids) grown from rectal biopsies, instead of based on typical genotyping only. In parallel with this H2020 project, our pharmaceutical partners will obtain market approval of their drug product candidates for common (F508del or gating) mutations in the CFTR gene. Ultimately, our project will enable ‘managed’ off-label access to these therapies towards patient groups or individuals who show response to the therapy in a prospective intestinal organoid test. One of the major impacts of this project will be the innovative methodologies to acquire reimbursement for current and future off-label treatments of people with CFTR mutations. This will represent a real paradigm shift in CF treatment as it implements a new type of personalized medicine paradigm based on organoids, by shifting therapeutic trials
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'New connections in low-dimensional topology: Relating Heegaard Floer homology and the fundamental group' to be submitted under Seventh Framework.

assistant: **Abstract**

Low-dimensional topology is a central and exciting area of 21st century research mathematics that has enjoyed a period of intense activity in recent years. On the one hand, steady progress in understanding the deep connections between group theory and three-manifold topology has led to the resolution of long-standing conjectures; on the other, the introduction of modern homological invariants (e.g. Heegaard Floer homology, Khovanov homology) have contributed new insight and perspective on old problems in low-dimensional topology while establishing a vibrant and active field of research exhibiting new ties to physics (e.g. recent work of Witten).  This project will treat a major open problem, raised by Ozsvath and Szabo, that is positioned at the nexus of these two areas:PROBLEM: Establish a relationship between the fundamental group of a three-manifold and its Heegaard Floer theory.Heegaard Floer homology presents a new tool -- with origins in physics and gauge theory -- for investigating orientable three-manifolds that is both extremely powerful and inherently different from the fundamental group.  While there are certainly hints that some aspects of the fundamental group might be captured by Heegaard Floer homology, perhaps the most surprising potential connection is formulated in joint work with Boyer and Gordon:CONJECTURE: An irreducible three-manifold is an L-space if and only if its fundamental group is not left-orderable.L-spaces are rational homology spheres with simplest-possible Heegaard Floer homology while left-ordersare auxiliary structures on a group. This project will make major progress on the PROBLEM above by approaching this CONJECTURE from a range of perspectives. It will employ and draw on techniques from representation theory and foliations, and mak
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Testamentary practices in the periphery of the ius commune tradition: freedom and oppression (c. 1420-1620)' (TESTAMENT).

assistant: **Innovation**

TESTAMENT, an interdisciplinary consortium of social and legal historians from the universities of Leuven, Kraków, Jena, Prague andWarsaw, will study dynamics of freedom and 'unfreedom', of power and oppression, through the lens of testamentary law andpractice in Western and Central Europe (c. 1450-1620), with a particular focus on the regions in the 'periphery' of the late medievaland early modern academic tradition. The project members will develop a language to transcend the traditional dichotomy between'freedom' and 'unfreedom' and will single out criteria that can be used to situate specific cases on this continuum. On the basis ofthorough archival and doctrinal-historical research, the project will single out the family, policy, jurisdictional and jurisprudentialdynamics that determined the extent to which people could dispose of their goods post-mortally.To this end, the consortium will train promising junior scholars into professional, critically-minded, communicative, cooperative anddigitally competent social and legal historians. The Ph.D. students will be integrated in a unique international network of scholarsfrom both law and social history. They will be trained in both disciplinary and transferable skills at summer and winter schools, atmonthly online seminars, through a secondment at another academic partner abroad and also through meaningful experiences incollaboration with non-academic actors (especially archives and musea).This project will open new scientific perspectives for research by using digital methods (especially HTR-tools) and will add newunedited material to existing open access databases for further research. Through social media, blogposts, (online) exhibitions, course materials for secondary school teachers, interdisciplinary university s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Linking Transcription Factor Binding Dynamics to Promoter Output' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Transcription is a stepwise process that is inherently dynamic. Different types of transcription factors are continuously interacting off and onto DNA, ""searching"" for appropriate interactions - each bringing different functions into play. The rates with which these factors interact with chromatin, their association and dissociation rates, dictate the outcome of ""steady-state"", developmental and rapidly responsive regulatory programs. Given the central role of transcription factors in biology and disease, it is remarkable that we know next to nothing about the dynamics of transcription factor-chromatin interactions.The objective of DynaMech is to implement technologies that will allow us to measure transcription factor binding dynamics (on- and off-rates) genome-wide, at binding site resolution. This will be applied to gain a systematic understanding of how these dynamics effect the function of transcription factors. Analyses will encompass components of the RNA polymerase II pre-initiation complex in yeast, as well as a comprehensive set of gene-specific transcription factors. For each of these factors we will determine the on- and off-rates genome-wide as well as the degree to which the mRNA synthesis rates from all promoters are dependent on the factor. This data will all be analysed in the context of nucleosome binding dynamics to understand the general principles of how chromatin-transcripton factor binding dynamics shape regulatory mechanisms.  Through modelling promoter output and by additional perturbations, these principles will be explored to understand which properties of regulatory DNA determine differential transcription factor dynamics thereby causing differential promoter behaviour.We are as yet far from predicting regulatory outcome from regulatory s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Nano Voltage Sensors' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

To understand how the brain works, tools need to be developed that will allow neuroscientists to investigate how interactions between individual neurons lead to emergent networks. Towards this goal, we will develop targetable voltage sensing nanorods that self-insert into the cell membrane and optically and non-invasively record action potentials at the single particle and nanoscale level, at multiple sites and across a large field-of-view. In semiconductors, absorption and emission band edges are modulated by an external electric field, even more so when optically excited electron-hole pairs are confined, giving rise to the quantum confined Stark effect. The physical origin of this effect is in the separation of photoexcited charges, creating a dipole that opposes the external field. The proposed sensors will optically record action potential with unique advantages not offered by other methods: much larger voltage sensitivity, high brightness, and hence single-particle voltage sensitivity, large spectral shift (affording noise-immune ratiometric measurements), fast temporal response, minimal photobleaching, large Stokes shifts, large two-photon excitation cross sections, excellent performance in the NIR, and compatibility with lifetime imaging. The proposed sensors could afford, for example, the recording of pre- and post-synaptic membrane potentials, sub-threshold events, ultrafast spiking, individual ion channel activity, or a release of ions from single Ca+2 stores. In addition, deep tissue imaging could be afforded by two photon microscopy and far-field non-linear temporal focusing combined with lifetime imaging. Here we seek to optimize all aspects of the sensors’ synthesis, functionalization, delivery, targeting and detection, in order to provide neuroscientists
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Best Training for Green and Silent Mobility (GRESIMO)' (GRESIMO) under Seventh Framework.

assistant: **Objectives**

Engineering for future mobility must be inspired by ecology and economy to enable green and silent vehicles. Current university based education is focusing on classical fields like mechanical engineering on one side with some aspects of Noise, Vibration & Harshness (NVH) and Light Weight Design (LWD) or like electrical engineering covering aspects of “Electrification” & “Hybridisation” on the other side.The proposed GRESIMO project (Best Training for Green and Silent Mobility) aims to bring together early stage researchers and experienced specialists from across industry and academia in Europe covering NVH, LWD and H/E disciplines to form a broad range of professional background. Recent research underlines the strong interaction and shows the often conflicting demands of these 3 topics. Consequently, an optimum for future vehicle development requires an interdisciplinary education in this triangle of topics.GRESIMO focus is to motivate and encourage early stage researchers for scientific work in the new interdisciplinary research fields NVH+LWD, LDW+H/E and H/E+NVH. The fellows will be trained and supported in their phase of doctoral thesis to find innovative PhD topics as well as to receive specific education in theoretical and practical trainings. The education will comprise existing lectures in the partner network as well as training specifically developed for the interdisciplinary needs.GRESIMO is formed by a group of participating hosts, combining leading education and research institutions as well as industrial enterprises in 6 countries of the EC. Thus the engineers will participate in both the scientific research work and the practical application of new methods of testing and simulation. They will profit from extended international knowledge after their academi