RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Controlled fusion of liposomes and cells: a new pathway for direct drug delivery' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Inspired by the natural membrane fusion machinery, the aim of this research line is to design a synthetic analogue in order to: 1) Understand the process of the peptide-controlled fusion of two membranes at the atomic, molecular and mesoscopic level. 2) Developing a new generic method for the controlled delivery of any (bio)molecule directly into the cytoplasm of a cell thereby omitting endocytotic pathways. This new paradigm opens many new applications in the fields of functional proteomics, genomics and siRNA-technology. Studying, imitating and dissecting processes from Nature and applying the underlying principles has been highly successful approach for many years and opened up new lines of research and applications which were previously unimagineable. Examples are the aptamer and antibody technology. I will use this learning-from-Nature approach to design synthetic analogues of the membrane fusion machinery to create new functions and/or applications which are currently non-existent. Membrane fusion is a key process in all living cells as it facilitates the transport of molecules between and within cells. A primary mechanism by which molecules are conveyed to the appropriate location is to encapsulate them in liposomes that deliver the cargo by fusing with the lipid membrane of the target cell or compartment. I will use synthetic analogues of the membrane fusion machinery to induce the controlled fusion between 1) specific liposomes and 2) liposome-cell. This approach opens up a new paradigm for the direct introduction of (bio)molecule into the cytoplasm of living cells omitting the endocytotic pathways for which the applications are only limited by one s imagination.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Multidisciplinary approach to multilayer monumental sites studies: the case of the Quirinal Hill in Rome' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The multiplicity of different historical phases can be considered one of the most singular characteristics of cultural heritage. Until today it has been clear that the scientific approach to this issue should use the developmental process as the main tool for both defining the historical phases and understanding the current state of historical heritage. Generally, it is necessary to distinguish between the diachronic and the synchronic studies, but at the same time it is mandatory to evaluate the connection between different historical layers. These opposing needs still represent a big problem that historical sciences are not always able to manage. The desirable multidisciplinary approach often produces mediocre results, while individual research generally lacks the complexity that always characterizes conservation and valorisation issues. Thus, the research project aims to discover a methodological approach that can bridge the gaps that are now often apparent between different studies. The main research goal is to define a specific digital platform for the management and consulting of the outcomes provided from the different scientific fields involved. This structure will allow to share the data collected easily, giving information about the different historical phases of a site as well as a global assessment based on its most significant transformations. The area of the ancient Temple of Serapis on the Quirinal Hill in Rome should be a good case study, that's mainly because of its complex stratigraphy. The research aims at covering the whole development period of the area by means of systematic data collection. The analysis of all different temporal phases will be fundamental for the implementation of a methodological strategy, able to involve different experts. The b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Haploid selection in animals' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Unlike in plants, selection during the haploid (gametic) phase of the life cycle has been assumed to be insignificant in animals. The main reason for this assumption is that gene expression in mature sperm was thought to be absent due to the densely packed nuclear DNA. However, there is increasing evidence that several genes are indeed expressed in mature sperm and hence may be under selection. Importantly, gene expression in mature sperm may lead to antagonistic selection between haploid and diploid phases, if the fitness effects of an allele are divergent in the two phases. The aim of the proposed project is to assess (i) the importance of haploid gene expression for sperm form and function and (ii) the existence of antagonistic selection between haploid and diploid life phases in animals. I will combine two important tools of evolutionary biology, namely experimental evolution and functional genomics to address these two questions. I will use the zebrafish Danio rerio as a study system, which is ideal because its entire genome is sequenced, many genes are annotated and it has external fertilization allowing in vitro fertilization assays. Allelic polymorphism will be estimated by assessing single nucleotide polymorphisms (SNPs) and will be linked with variation in sperm form (morphometry) and function (motility and longevity). The project will be hosted by Professor Göran Arnqvist and will be in collaboration with Professor Hans Ellegren, both at the Centre of Evolutionary Biology (EBC), University of Uppsala, Sweden. The EBC hosts one of the largest accumulations of evolutionary biologists in the world, and it provides an extremely active and simulating research atmosphere. The proposed project will allow me to establish myself as an independent researcher and will b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Future Seaplane Traffic - Transport Technologies for the Future' to be submitted under Seventh Framework.

assistant: **Abstract**

IATA forecasts an annual air traffic growth of at least 5% for the coming years. As a consequence the capacity overload of current airports has considerably grown. The huge shore lines and number of islands in Europe which were increased by the new EC member states offer a great potential for an international air traffic system uisng seaplanes and amphibians. With these vehicles new traffic routes can be developed with the advantage of using natural landing strips. By using amphibians direct connections from shorelines to airports can be realised. The mobility of a large population will be improved. Operators and entrepreneurs interested in starting new seaplane businesses report about missing modern airplanes, international standards and rules and missing expertise of various stakeholders. Based on this preliminary analysis the proposal aims to investigate the today´s seaplane situation and to evaluate the weaknesses and strenghts and to elaborate a set of concepts and requirements for a future seaplane air transportation system for Improving passenger choice in air transportation" including technical requirements for " new vehicles". The elaboration of new concepts shall be based on existing experiences and its evaluation and on research work focussing on future oriented traffic system concepts including the integration into a sea/air/land traffic chain. In order to collect all available experiences and ideas as a basis for effective future traffic concepts workshops shall be organized by bringing together all relevant stakeholders. One workshop shall be arranged in the Mediterreanean (Greece, Italy or Spain) one in Poland and one in GB or France. The workshops will support the dissemination of the SA results and of FP7 and ACARE policies, too. Beside the reqirements
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Safe and efficient hydrocarbon oxidation processes by kinetics and explosion expertise and development of computational process engineering tools: safekinex' in the context of a Fifth Framework call.

assistant: **Objectives**

Process industry is challenged to produce higher product yields at lower costs and less waste while maintaining safety. Sustainable growth requires more partial oxidation of hydrocarbons and biomass. Such developments will increase explosion risk. Risk can be reduced by reliable process design and control tools, which in turn depend on experimental data and models related to extreme process conditions. Presently such data are almost non-existent. SAFEKINEX is an RTD project aiming to fill this gap, through a combination of detailed chemical kinetic insight and a hierarchy of computer models. Experiments up to 500 C and pressures up to 100 bars, will enable development of appropriate explosion safety prediction tools. The end results of the project will include an Expert System for explosion hazards in hydrocarbon-oxygen containing systems and a computational fluid dynamic package to examine the effect of plant environment on these indices.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The impact of bone-marrow derived cells on tumor growth and metastasis after cytotoxic anti-cancer drug treatment' (2007-2013) targeting Seventh Framework.

assistant: **Abstract**

One of the more important recent developments in clinical oncology has been the approval of antiangiogenic drugs for the treatment of various types of cancer. We have found that these drugs not only act locally to inhibit the formation of new blood vessel capillaries in tumors, but also systemically by targeting bone marrow-derived endothelial precursor cells (CEPs). It has been suggested that other bone marrow-derived cell (BMDC) types contribute to tumor angiogenesis and growth by either directly incorporating to the vessel lumen or by residing at preivascular site - promoting angiogenesis by unknown paracrine mechanisms. With respect to CEPs, there is an ongoing controversy about their relative contribution to tumor blood vessel formation, in large due to a number of studies which reported low or even no detectable incorporation of such cells to the lumen of tumor blood vessel capillaries. We have recently shown that there are circumstances, namely, after acute cytotoxic drug therapy using vascular disrupting agents, or chemotherapy drugs including pactliaxel, 5-flourouracil, and docetaxel, where levels of CEPs are acutely mobilized from the bone-marrow niche, and subsequently colonize the drug-treated tumors, where they can make a significant contribution to tumor re-growth. These observations suggest a new perspective as for the role of CEPs in tumor angiogenesis and growth. Here, we propose to evaluate the contribution of different BMDC types to tumor angiogenesis and growth, and their contribution to metastasis seeding after treatment with cytotoxic anti-cancer drug therapies. In addition we will identify the various host factors and cytokines which promote BMDC mobilization and tumor homing. A major emphasis will be placed on new treatment strategies that can in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Tuning Attention during Language Learning' (TUNINGLANG).

assistant: **Concept**

Language is the most amazing skill that humans possess. It allows social interaction, can make us cry, laugh and transmit our most complex thoughts. Comprehending the cognitive processes involved in language learning is of critical importance for our understanding of why under certain conditions language learning is impaired. However, current language learning research has often offered limited explanations bounded within the language domain, ignoring the importance of other cognitive functions. The present project breaks these limits and presents an integrative approach at the edge of different research fields to understand the role of attention during language acquisition. Because speech is a sequence of sounds that unfold in time the present proposal integrates this long ignored temporal dimension. The aim of the project is thus to understand the involvement of the temporal orienting brain networks in language learning and how the attentional system may be tuned to the acquisition of words and rules. Three specific objectives will be fulfilled: (i) delineating the temporal attention mechanisms and brain networks involved in language learning, (ii) uncovering the developmental relationship in infants between these specific attentional mechanisms and word and rule learning, and (iii) understanding how the deficits in temporal orienting and the lesions in its brain networks may lead to similar deficits in language acquisition. This project uses a combination of novel methods allowing linking structural and functional measures (analysis of oscillatory activity following EEG variations during learning, fMRI – structural MRI white matter tractography and TMS) in different populations (brain-damaged patients, infants and healthy adults).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Analysis of the Cost Structures of the main TEN Ports' to be submitted under Fourth Framework.

assistant: **Abstract**

Assessment of the positive and negative impacts resulting from the introduction of new charging and financing principles both on the European port system as a whole and on different types of ports (e.g. ports can be classified in terms of ownership structure, traffic flow diversification, port functions, etc.).A comprehensive state-of-the-art analysis in order to include all impacts that have been identified in the relevant port economics, academic and professional literature.Identification of existing practices and the practical relevance of potential impacts where these practices changed will be explained and assessed by those who implement specific port financing and port charging systems in the European port sector, i.e., the port authorities themselves and the regional/national agencies responsible for administering financing and pricing schemes. The views of these actors as well as those of a number of key organisations such as ESPO, FEPORT and ECSA will be explicitly taken into account when assessing possible impacts.Given the outcomes of the above mentioned a number of simulations will be performed associated with introducing alternative pricing and charging schemes in the European port system. The results of these simulations will then be compared with experiences in countries where such schemes (e.g., cost recovery) have already been implemented. %. %The project's main links are with the Commission's Green Paper on Seaports and Maritime Infrastructure (COM (97) 678 final, 10 December 1997) and with the Commission's policy on extending the TEN-T to include, inter alia, seaports (see, e.g., Proposal for a European Parliament and Council Decision no. 1692/96 EC as regards seaports ...; COM (97), 681 final, 10 December 1997). In a broader sense it is also related
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'A Conceptual History of 'Tradition' in the Modern Arab World: Egypt and Greater Syria in the 19th and 20th Centuries' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Tradition is a key analytical concept in the study of Islam, Muslims, and the Middle East in western academia. In late 19th and early 20th-century  discourses, the concept elicited negative connotations, such as stagnation, backwardness, and irrationality. In recent decades,  scholars revised these earlier conceptions of tradition, foregrounding the ability of a tradition to adapt and change.  This reformulated understanding of tradition undergirds Talal Asad’s theorization of Islam as a “discursive tradition,” an analytical approach that has dominated the field of Islamic studies.  Yet in Arabic, there is no single equivalent to the Anglophone concept “tradition.” Indeed, several distinct Arabic terms, including taqlīd, turāth, sunna, naql, and others, are often equated with “tradition,” even though their usages, histories, political mobilizations, temporalities, counter-concepts and affective valences differ from each other as well as from the Anglophone concept. In this action, I will conduct a diachronic and synchronic analysis of the semantic network of Arabic concepts often equated with the Anglophone concept “tradition” in Egypt and Greater Syria in the 19th and 20th centuries. The methodology for this action includes the close reading of Arabic texts representative of major intellectual and ideological currents in the modern Arab and Muslim world, as well as quantitative analyses that chart the distribution and frequency of these concepts in Arabic periodicals and other salient texts in the same period. The larger aim of the project is to integrate the experiences and worldviews reflected in Arabic concepts into the analytical vocabulary that structures the study of Islam, Muslims, and the Middle East in western academia.


**Keywords:** Conceptual history, mode
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'LaSER MATTER INTERACTION: NON-LINEAR PROCESSES AND HIGH RESOLUTION SPECTROSCOPY IN THE TIME AND FREQUENCY DOMAIN'.

assistant: **Innovation**

LENS, the European Laboratory for non-linear Spectroscopy is associated to the Florence University as an European Facility devised to provide advanced laser and spectroscopic facilities for European researchers and to promote the exchange of ideas, scientific techniques and technical skills. LENS has a permanent administrative, technical and research staff which assist visitors for the execution of their experiments and offers a broad variety of experimental facilities for spectroscopic researches, covering the frequency domain from the far IR to the extreme UV with the highest available resolution, and the time domain with temporal resolution ranging from few femto- up to nano-seconds. LENS is equipped to conduct research in the field of ultrafast processes in condensed matter, in atomic and molecular very high resolution spectroscopy, in standard and time resolved Raman and in the spectroscopy of supersonic jet cooled molecules. LENS is a partner of a cluster of European Large Scale Facilities, including, in addition to LENS, the LIF-ENSTA (Palaiseau, France). the FORTH (Heraklion. Greece), the LLC (Lund, Sweden) and the MBI (Berlin, Germany) laboratories. LENS offers each year 600 man-days of use of its facilities and the necessary scientific and technical assistance and collaboration to European scientists.