RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Statistical Tools for Reaction Efficacy AssessMent: Prediction and Understanding in Organocatalyst Discovery' in the context of a Horizon 2020 call.

assistant: **Objectives**

This proposal seeks to further develop Statistical Tools for Reaction Efficacy AssessMent (STREAM). The goal is to build small ligand sets to screen for statistical training of correlations, identify the parameters that are most likely to describe selectivity trends for particular catalysts, and develop a virtual screening deck that allows for rapid identification of improved performers. For this proposal we will evaluate peptide-based catalysts and N-heterocyclic carbenes (NHC) on various mechanistically distinct catalytic processes, to predict and understand reaction performance. The proposed STREAM methodology not only allows for effective prediction, and thus the design of better performing catalysts, but also is a contemporary approach to mechanistic study. These modern tools are general and applicable in principle to any chemical system, thus, directly relevant to each research group developing asymmetric or site-selective reactions. The experienced researcher proposes to undertake the outgoing phase within Professor Matthew Sigman’s research laboratory (University of Utah, USA) and undertake the incoming phase within Professor Frank Glorius’ research laboratory (Westfälische Wilhelms-Universität – Münster, Germany); both proposed supervisors are experts in the mechanistic study of asymmetric catalysis (with complementary skill sets) and highly prominent figures in the field of catalyst design.


**Keywords:** Catalyst design, Organocatalysis, Multidimensional reaction analysis tools, Data-driven reaction optimisation, Computationally derived parameters
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'c-GMP compliance of C-stem, an IPSc based cell therapies production technology'.

assistant: **Innovation**

Scaling-up cell therapy manufacturing provides many benefits: the capacity to replace failing tissues in patients suffering from incurable chronic or degenerative diseases, affordable treatments and the economic viability of the development of cell therapies for rare diseases. The baseline of TreeFrog Therapeutics (TFT), “Cell Therapy for All”, encapsulates this vision.TFT has already obtained outstanding results with its C-StemTM stem cell culture technology, fully scalable and allowing a high cell multiplication factor.The cell therapy market has boomed since 2012. In 2018, 1,028 clinical trials were underway according to the Alliance for Regenerative Medicine and big pharmas invested €6.2bn in cell therapy programs. The FDA anticipates to approve « 10 to 20 cell and gene therapy products a year » by 2025.A critical bottleneck remains for the cell therapies that will reach the market within 5 to 10 years: the industrial production of human induced pluripotent stem cells, the raw material for cell therapies. Current manufacturing models do not meet the standards of regulatory authorities and healthcare systems in terms of safety, cost, volume and lead time. With C-StemTM, TFT is in the best position to become the global supplier of stem cells for cell therapy’s industry.Tailored for cost-killing mass-production of stem cells, while defining a new quality standard for cellular products, C-StemTM needs to be certified for “Good Manufacturing Practices” (GMP) to be used in clinical settings and capture its market. This project requires, within 24 months, to develop a GMP encapsulation device, to replace non-compliant materials, while developing relations with EU/US regulatory agencies and clients from the pharmaceutical industry.TFT has a “go-global” strategy and aims at
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'EMbedded MONitoring', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The vision of smart locations is of significant societal interest today. For example, a smart city can monitor its levels and distribution of air pollution and give recommendation to European citizen about where to walk and where to drive. This helps to improve sustainability of urban life. This societal vision requires however that monitoring of huge geographical extensions is performed in real time. The EMMON project aims to allow such monitoring using Wireless Sensor Network (WSN) devices – small communicating & cooperative nodes with sensors.In order to achieve this ambition, EMMON will perform technological research at the level of devices, in new, efficient, and low power consumption communication protocols, embedded software with better overall energy efficiency, secure, fault-tolerant and reliable middleware for large scale monitoring and remote command & control operational systems for end-users. The project will deliver results in all these fields.All research and development efforts are targeted to allow the use of thousands of devices in distributed large scale networks.The objective is to accomplish that these embedded devices can be placed in the environment to perform continuous monitoring and situation analysis, targeted at specific scenarios (water pipelines, urban quality of life, forest and marine environments, civil protection) detecting abnormal variations and broadcast rapidly alarms and alerts.The quantified goal of the project is to create technologies that allow effective monitoring with 10,000 to 100,000 devices, monitoring an area of 50 square km in a real world scenarios. This would advance WSN deployment size by one order of magnitude. The consortium will use simulation to test if advancements of two orders of magnitude are possible with the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Cybersecurity Protection for Cyber-Physical Systems Against Integrity Cyberattacks'.

assistant: **Objectives**

Dr Kangkang Zhang will carry out a project to concern cybersecurity protection for cyber-physical systems against integrity cyberattacks (CSP-CPS-A-ICA) by revealing the stealthiness of integrity attacks and then developing detection and distinction methodologies and schemes from control perspectives. This research aims to provide effective, efficient and reliable cybersecurity protections for industrial control systems (ICSs). The project will be carried out in the Control and Power (CAP) research group, within the Department of Electrical and Electronic Engineering (EEE), at the Imperial College London (Imperial), under the supervision of Prof. Thomas Parisini. As a part of the project, I will carry out two 3-month secondments in the KIOS Research and Innovation Center of Excellence (KIOS CoE), at the University of Cyprus (UCY). The expected benefits of this project are to achieve the above research aims and enable me to make a leap in my career as well as to create a close collaboration between Imperial and UCY in the cybersecurity-related research areas.


**Keywords:** Cybersecurity, Cyber-physical Systems, Attack Detection, Risk Distinguishing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Video analysis for Investigation of Criminal and TerrORIst Activities'.

assistant: **Innovation**

Video recordings have become a major resource for legal investigations. Since no mature video investigation tools are available and trusted by LEAs, investigators still need to carry out the analysis of videos  almost exclusively manually. Current practices are too resource intensive to handle the yet huge and steadily increasing volume of videos that need to be analysed after crimes and terrorist acts. The consequence is that LEAs cannot analyse all available videos because of the huge effort needed, and the extraction of first clues from videos after a terrorist attack takes more time.VICTORIA will address this need and deliver a Video Analysis Platform (VAP) that will accelerate video analysis tasks by a factor of 15 to 100 (depending on the use case), while providing very reliable results. To achieve this, VICTORIA will 1) develop a set of TRL-6 video analytics selected for their relevance in video investigation related to crimes and terrorist acts, 2) increase significantly the usability of delivered tools by involving LEAs directly in all stages of the development process, from specifications, over assessment of several VAP prototype versions, up to field trials in LEA operational conditions, 3) create an ecosystem around an open VAP concept, that will facilitate sustainable innovation and market growth for video investigation products, 4) train LEA investigators in the use of the VAP, 5) ensure that VICTORIA activities and results meet EU Legal-Ethical-Privacy rules. The VAP will have a scalable architecture based on big data technologies, feature new user interface paradigms allowing complex semantic  investigation queries and 4D crime scene reconstruction, be adaptable to specific user needs,  and be future proof thanks to an open analytics plug-in feature, bas
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'COordination MEchanism for Cohorts and Trials' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

The overall goal of COMECT is to coordinate activities across Europe’s strategic adaptive platform trials (APTs) and cohort studies (CS) on infectious diseases (IDs) with epidemic or pandemic potential, by overseeing and facilitating dialogue, sharing of good practices, promoting collaboration and coordination across studies and providing updated information on initiatives and innovation in ID clinical research.COMECT will build on and strengthen existing networks and infrastructure. These include EU-funded coordination mechanisms and networks, namely the Trial Coordination Board (TCB), Joint Access Advisory Mechanism (JAAM), the Cohort Coordination Board (CCB), and the ECRAID Coordinating Comittee. COMECT will develop a visible, well-defined coordination mechanism to highlight Europe's capacity and competence as an attractive base for clinical research.COMECT will deliver:1) an expanded, combined  European coordination mechanism that will work on harmonizing research initiatives, exchange of good practices, and stakeholder engagement across ID clinical studies in outbreaks and during inter-epidemic phases;2) a strengthened JAAM to support coordination through independent scientific assessment of compounds/vaccines and recommendations for APTs to evaluate the new compound in new or adapted platform trials;3) the mapping of stakeholders and their respective activities relevant to APTs and CS;4) a harmonised approach cross-study identification, assessment, and reuse of participant-level data from European APTs and CS;5) coherent communications and stakeholder engagement across all activities;6) a sustainability plan for the continuation of activities beyond the funding period.COMECT will quickly adapt coordination efforts to a changing research landscape and to new ID thr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Geometry of groups and manifolds' (GEOMGROUPSMFLD).

assistant: **Innovation**

The project falls within the framework of research in geometric group theory, a new research field that combines the techniques and results of classical fields as geometry and group theory. This bridge between these fields gave rise to a quick and fruitful development of group theory, providing techniques to solve classical problems and opening new borders and horizons of research.In particular, many computational problems that seemed quite hard using traditional viewpoints, have been solved via a geometric approach. Moreover, the very active moment of low-dimensional geometry (e.g. solution of Poincare, Geometrisation and Ending laminations conjectures) is now reflecting in geometric group theory, which is now under the spotlight of the whole international mathematical community.During his Marie Curie Intra-European Fellowship, the researcher had the occasion to collaborate with the most important scientist in geometry and group theory, and the skills he acquired in that period permitted him to give important contributes to European research in geometric group theory.The main purpose of the project GEOMGROUPSMFLD is to consolidate and increase the connections and contacts of Francaviglia with his international collaborators, and to create an active research group in geometric group theory in Pisa, Italy - the country of provenience of the researcher - where strong research groups in geometry and group theory are already active.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Dielectric and magnetic properties of magnetic liquids, as two-phase dispersions' (1994-1998).

assistant: **Innovation**

Research objectives and content Magnetic fluids are dispersions of magnetic nanoparticles in a carrier liquid. They consist an important novel class of materials, which finds a wide variety of industrial and biomedical applications and is of increasing technological interest. Aim of the project is to study the dependance on the microstructure (chain-formation, agglomeration) of the magnetic and dielectric properties of dispersions. Ferrofluids are unique in offering the possibility to alter the topology in a continuous way through an external macroscopic parameter (magnetic field). The results of broadband dielectric and magnetic spectroscopy (DC to 2GHz) at temperatures down to -100rC will be compared with numerical simulations, morphological studies (X-ray diffractometry) and effective medium theories. We expect to enhance the theoretical unterstanding of the correlation between topology and effective properties of ferrofluids and two-phase suspensions in general. Training content (objective, benefit and expected impact) Both the experimental and the theoretical/numerical part of the project will be conducted by me, as a part of the requirements for a doctorate. I consider this as a unique opportunity to train in many aspects of basic and applied research. I will have the opportunity to work with state-of -the-art equipment and techniques in the field of spectroscopy and novel-material science. The benefit from the excellent experience of the host group should be underlined. Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project '“Enhancing Safety and security aspects in Transport rEsearch in the EuroMediterranean region”' (ESTEEM) under Seventh Framework.

assistant: **Objectives**

ESTEEM aims at contributing to the coordination of research activities and policies between the EU and the Neighbouring Countries on transport issues. More specifically, its aim is to strengthen and enhance the links between Maghreb and the neighbouring EU countries – namely Italy, France and Spain - in order to identify strategic priorities and topics for high quality researches on safety and security in transport system and infrastructure.  The project has been outlined by a consortium consisting of seven organizations with different but complementary field of expertise related to transportation. Each partner represents a country of the selected area of intervention, which means a well-balanced geographical distribution and a consequent higher number and range of potential beneficiaries to be reached.  The proposal is structured according to the following method: • the state of the art on safety and security related research in the selected region will be analyzed;  • specific sub-areas will be identified according to the main needs in the domain of transport system safety and security; • surveys will be conducted on each sub-area in order to identify priority research actions to be undertaken; • a series of workshops will be organized in order to validate the surveys’ results, with the aim of identifying specific topics and defining potential guidelines and roadmaps for future research;  • an ad hoc network will be set up with the aim of fostering collaboration among the participant and disseminating the project’s results to an as wide as possible range of stakeholders.   Relevant stakeholders and other interested entities will be invited to join the network, hence improving collaborations at all levels. Co-ordination of research activities and policies on transport
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Cellular Analysis with Multi-Sample MRI Platform' (CAMP), addressing dissemination and exploitation.

assistant: **Impact**

CAMP project seeks to translate the hyperpolarisation-enhanced magnetic resonance metabolic imaging platform, developed under the ERC-funded project Lifetime Metabolomics for Paediatric Liver Cancer Detection and Therapy Assessment Using Organ-on-Chip Platforms (LIFETIME), into a commercially viable solution for multi-sample metabolic analysis. This Proof of Concept (PoC) grant will focus on validating the platform's commercial viability, technical feasibility and IP positioning, with the ultimate goal of moving towards commercialisation in research and clinical environments, particularly for rare disease applications. The platform integrates microfluidic chips capable of cell media recirculation and hyperpolarised substrate injection with multi-channel MRI technology, enabling the simultaneous analysis of up to 30 samples. This integration will significantly improve signal-to-noise ratio and throughput, reducing the number of cells required per sample by over 50%, which is crucial for rare diseases like hepatoblastoma where patient material is limited. We will refine and test the system in both preclinical and clinical settings, validating its performance and scalability. In parallel, we will explore commercialisation pathways and establish an intellectual property strategy to ensure protection and enable future licensing or partnerships. By enabling high-throughput, high-sensitivity metabolic profiling, this project has the potential to provide deeper insights into disease mechanisms and treatment response, paving the way for personalised medicine and more informed drug administration strategies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Fluorescence lifetime optical biopsy system' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The ultimate goal of this Fellowship is to train a talented researcher through a research project focused on the development of novel tools for the in vivo real-time assessment of the respiratory chain activity (NADH/FAD ratio) and mitochondrial dysfunction in tissues. This will be achieved by means of both laser fluorescence spectra and lifetime fluorescence data analysis, supplemented with additional optical measurements (laser Doppler flowmetry, tissue reflectance spectroscopy) in order to correct the impact of affecting factors (changes in blood perfusion, blood volume, blood oxygenation). The Fellow – Dr. Evgeny Zherebtsov – will be trained in biomedical optics, a fast growing field of science and medical application.He will receive access to a unique training experience at the host – Aston Institute of Photonics Technologies (AIPT), Aston University (Prof. E. Rafailov), and at academic and industrial secondment partners: University College London (Prof. Andrey Abramov), University of Bari, Italy (Prof. Annamaria De Luca), Axxam S.p.A., Italy (Dr Jean-Francois Rolland). The FORECAST outputs will be relevant to the EU life sciences sector by offering new cost-efficient technologies for real-time in vivo screening studies of metabolic activity in application of testing of new chemicals for efficacy and safety in small animals and test tubes during drug discovery and epithelium cancer diagnostics. The products transformed from the FORECAST outputs will contribute to the enhancement of EU scientific excellence. The project brings together a talented young Fellow with a strong biomedical science and engineering background, and an internationally growing group of researchers at Aston University with expertise in the area of developing laser-based photonic devices for bio