RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Development of advanced sweet potato (ipomoea batatas) genotypes resistant to the complex of potyviruses infecting sweet potato in china' to be submitted under Fifth Framework.

assistant: **Abstract**

The objective of the project is the development of sweet potato genotypes resistant to the complex to Potyvirusesprevailing in China in order to be fed into national breeding programmes. The project aims at overcoming the scarcity of sources of resistance in the sweet potato germless. It is organised in 3 parts. Detection and characterisation of resistance sources among existing or old varieties of the crop, wild forms of the same species, or closely related species'. Development of engineered resistance by cloning single chain antibodies (scoff) targeting the coat proteins or the polymerise of the sweet potato Pot viruses, and using Agro bacterium and particle gun mediated genetic transformation without resorting to selectable markers. The characterisation of the biological components of virus resistance that could contribute to slow down the polycyclic building up of virus epidemics
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Combinatorial use of cannabidiol and the serine hydrolase inhibitor AKU-005 to enhance endocannabinoids for treatment of migraine', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Migraine is a common multifaceted neurovascular disease. Traditional medications have limitations and even newer CGRP monoclonal antibodies only effectively treat 50% of patients. Instead of using highly addictive painkillers, such as opioids, there is a great need for alternative, effective and safe medications. Despite psychoactive side-effects of cannabis, its derivative compounds (cannabinoids) have emerged as a new class of analgesic and anti-migraine agents. Indeed, the frequency of migraine headaches decreases with medical marijuana. To avoid cannabis psychotropic effects, an alternative is to recruit the anti-nociceptive actions of endogenous cannabinoids (endocannabinoids). The two main endocannabinoids are 2-arachidonoylglycerol (2-AG) and anandamide (AEA). The anti-nociceptive efficiency of 2-AG and AEA is determined by their enzymatic synthesis, activity on receptors CB1 and CB2, and degradation by monoacylglycerol lipase (MAGL) and fatty acid hydrolase (FAAH), respectively. There is recent progress in the development of selective and potent MAGL and FAAH inhibitors, providing excellent starting points for enhancing endocannabinoid activity. A key point is that the enzymes are distinctly active in different migraine pain signaling areas. Therefore, we propose that at least a dual FAAH and MAGL inhibition would be ideal. We have shown that the serine hydrolases inhibitor AKU-005 potently reduces migraine-related nociceptive activation. Of further relevance, the combination of CB1/2 orthosteric delta-9-tetrahydrocannabinol (THC) and allosteric cannabidiol (CBD) agonists can reduce central and peripheral-induced light aversion in CGRP migraine models. Our hypothesis is that enhancement of endocannabinoids by the inhibitor AKU-005 in combination with CBD treatme
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Fire in the land of ice: Climatic drivers and feedbacks' in the context of a Horizon 2020 call.

assistant: **Objectives**

2019 was the largest fire year since at least 1997 within the Arctic Circle, largely driven by Siberian fires. The arctic-boreal region stores about two atmospheres worth of soil carbon with 90 % currently locked in permafrost soils, or perennially frozen ground. Fire releases parts of this carbon stock, which may induce a vigorous climate warming feedback.FireIce will investigate feedbacks between climate warming and arctic-boreal fires by studying direct and longer-term carbon emissions from fires. FireIce will acquire highly needed observations of carbon emissions from Siberian forest and tundra fires. On top of the direct fire emissions, fires accelerate permafrost degradation, which leads to greenhouse gas emissions for several decades. Their sum may be substantially larger than the direct emissions, yet is largely unknown. In addition, FireIce will investigate the relative contribution of CH4 from smoldering fires to fire emissions. CH4 emissions represent a small, yet not well known, fraction of carbon emissions from fires, but CH4 is a more potent greenhouse gas than CO2.FireIce will investigate feedbacks between climate warming and arctic-boreal fires by studying controls on fire size and ignition. Fire growth can be limited because of fuel or fire weather limitations. The fire weather control is sensitive to warming, which may lead to larger future fires. Lightning ignition is the main source of burned area in arctic-boreal regions, and more lightning is expected in the future. By combining contemporary controls on fire size and ignition, and future predictions of climate and lightning, FireIce will assess the vulnerability of arctic-boreal permafrost and soil carbon to increases in fire. FireIce’s results will be relevant to evidence-based policy. FireIce’s i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Research and Innovation in the service of Economy and Society EU Neighbourhood and the Black Sea region' to be submitted under Seventh Framework.

assistant: **Abstract**

In a multi-polar and rapidly changing world the European Union is a world-class player and its policies have an impact at global level. In this respect, policies for International Cooperation/INCO in S & T & I between EU countries (and associated countries) and /or third countries, highlight and enhance the EU role in response to the societal challenges worldwide. In this regard, the proposal suggests the organization of a Conference, namely RInES, under the auspices of the Greek Presidency of the European Council. Its overall objective is to highlight the crucial INCO’s role for the EU by reinforcing its collaboration with the European Neighbourhood and Black Sea region within the framework of the HORIZON2020. Within the framework of the Conference, the EU INCO’s policy will also be demonstrated addressing the new trends and emerging societal challenges, such as Environment/Marine Research and Sustainable Energy, Clean and Decarbonized Economy. Furthermore, the event will promote the role of the industrial sector by bringing together RTD&I participants from the public and private sector, thus mobilizing the service to economy and society. The Conference will take place in Thessaloniki in May 29th-30th 2013. It is also envisaged to result in a Joint Declaration, the “Thessaloniki declaration”, accompanied by a Roadmap presenting the future steps for the EU INCO Policy and external R&I relations in the above-mentioned target countries.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'TECHNOLOGY FOR THE IMPROVEMENT OF SPORTS PERFORMANCE IN NON-PROFESSIONAL CONTEXTS' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Realtrack Systems is a company specialising in the development and commercialisation of sports and health-oriented innovative technological solutions whose goal is to improve performance and well-being by monitoring and analyzing various parameters related to participation in sports activities.The use of technology applied to sports has been a growing trend in the recent years, particularly significant among non-professional athletes who are increasingly interested in using technology to improve their personal performance. These individuals demand products in this line that are adapted to their needs, that is, products with high-tech features that are reasonably priced, easy to use and adapt to any sports discipline.  WIMU Active is the solution developed by Realtrack Systems for this market segment; consists of a small and robust wearable device with associated software, for enhanced data capture and advanced monitoring analysis used in performance improvement of key parameters related to participation in competitive team sports activities, cost effective to specifically fill the elite amateur and sub professional sportsman segment need.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Viscous effects on Wind turbine blades', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Objectives The objective of the project is to analyze and clarify the aerodynamic mechanisms underlying the production of blade forces on rotors of wind turbines. For this state-of-the-art Navier-Stokes solvers with appropriate transition and turbulence modelling will be utilized. Dynamic stall and 3-Dimensional stall will be addressed. A parametrical study will be undertaken in order to elucidate the influence of aspect ratio, twist, chord- and thickness-distribution on the stall characteristics of rotating blades. Technical Approach The Navier-Stokes algorithms will be validated against measurements from the available literature and previous Joule projects. Of particular interest will be the assessment of the influence of turbulence models and transition criteria on the solution. Both conventional airfoil shapes and special-purpose wind turbine blades will be considered. It is expected that this task may form the basis for adapting and improving the algorithms to handle massively separated flow fields. Dynamic stall calculations will be performed using 2D and quasi-3D Navier-Stokes algorithms. The most important parameters influencing dynamic stall characteristics are the mean angle of attack and the reduced frequency. To analyze the effect of rotation on 3-dimensional stall characteristics of wind turbine blades a series of Navier-Stokes calculations will be carried out for various blade geometries. As such calculations are very computing demanding, requiring in the order of 1 million mesh points for one blade, only steady calculations will be performed. Of special interest is to clarify the influence of blade planform, twist and airfoil type. Expected Achievements and Exploitation It is expected that the project will result in useful information from the following a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Flexible Ecological Multipurpose Advanced Generator (FEMAG)'.

assistant: **Concept**

aFEMAG targets an energy generator BOX, closed, of small power, based on the integration of a fuel cell in the range of 0.125 to 1 kW with a battery pack and supercapacitors, for the flexible supply at variable power of small portable non automotive devices. composed of all those companies manufacturing systems potentially suitable to be supplied by fuel cells, but of size and value lower that those presently requested for an ad hoc development of similar systems. The project is targeted at SMEs, and will produce also an advanced expert system for the design of complex generators based on FCs in the range of 0.125 to 1 kW. FEMAG proposes to develop a product which is based on Fuel Cells, but is combined with all the components required to make its application flexible, simple and able to satisfy not only the base power consumption, but also relative peaks of consumption of associated machines, within utilisation profiles prefixed at the design stage. There exists a clear and remarkable target market for such systems, composed of all those companies manufacturing systems potentially suitable to be supplied by fuel cells, but of size and value lower that those presently requested for an ad hoc development of similar systems. The approach proposed by FEMAG is very original and with impressive replication potential, since, further to the development of prototypes optimised by experimental design for the specific target applications of the project, it envisages the application of advanced mathematical methodologies in order to formalise and patrimonialise the knowledge generated by the project into an expert system for virtual design of integrated generators based on FCs.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'ANTIVIRAL, ANTIBACTERIAL & ANTIFUNGAL NANOCOATING PLATFORM' under Horizon Europe.

assistant: **Concept**

The NanoBloc consortium of 4 leading universities & institutes, and 5 companies (3 SMEs & 2 large enterprises) will develop & upscale (from TRL3 to TRL6) new all-European antimicrobial, antifungal & antiviral coatings made by industrially scalable, green technology suitable for application on a variety of substrates- porous filter materials (air filtration units, face masks), textiles (protective clothing, mattress covers, aprons, wallpaper), & on a variety of high-traffic solid surfaces (door knobs, handles, handrails, sanitaryware-taps, etc.). A research line will focus on thin coatings- <200 nanometers- deposited by Physical Vapour Deposition, formed by a glass and/or ceramic matrix (e.g. silica) capable of incorporating silver or other metal nanoparticles, which can be applied on countless substrates. These coatings allow a gradual release of ions without dispersing the nanoparticles in the surrounding environment & have demonstrated their effectiveness toward proliferation of bacteria, fungi & viruses including respiratory syncytial virus, influenza virus A & with demonstrated virucidal effect towards SARS-CoV-2 on face masks. They can withstand temperatures up to 450 degrees celsius without altering their antimicrobial properties, thereby suited for thermal regeneration.In addition, the project will build on previous work in obtaining coatings effective against a range of pathogens using technologies such as UV cured lacquers, sol-gel and electrophoretic deposition. A key strength in our approach is in merging these research lines to obtain innovative products that will be brought to market by our industry participants.New knowledge generated in the project on antiviral mechanisms & coating durability in operating conditions, will be used to select the most suitab
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Photonic Wafer-Level Integration Packaging and Test' (PhotonicLEAP).

assistant: **Innovation**

PhotonicLEAP will develop a disruptive wafer-level PIC module integration, packaging and test technology which can be scaled from low to very large volumes. PhotonicLEAP will use this disruptive technology to produce a revolutionary Surface Mount Technology (SMT) PIC package, which for the first time incorporates multiple optical and electrical connections. SMT is the most widely used, cost-effective and standardised package in the electronics world and PhotonicLEAP’s standardised SMT approach is set to follow, becoming a new global standard for cost-effective PIC packaging and high-throughput PIC testing. PhotonicLEAP will also develop standardised packaging design rules formalised into a Process Design Kit (PDK), providing users with easy access to the project technology through Open Access and commercial PIC design software tools. The project will validate these technologies through two state-of-the-art demonstrators, including a high-speed optical communication module and a portable medical device for cardio-vascular diagnostics. PhotonicLEAP’s approach will reduce the cost of PIC production by over 10 times, revolutionising existing applications and creating completely new markets. The project workplan includes high-quality measures to Exploit and Disseminate PhotonicLEAP’s results, including management of IP and research data, and to Communicate project activities to different target audiences. A key exploitation measure involves technology transfer to the flagship European PIC Packaging Pilot Line, PIXAPP, which has an extensive and growing user-base across multiple markets. PhotonicLEAP will be delivered by a highly experienced consortium with an unmatched record of excellence in developing and delivering many world firsts in PIC packaging, test technologies and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Untangling Ediacaran Paleomagnetism to Contextualize Immense Global Change' (EPIC) under Horizon Europe.

assistant: **Objectives**

The Ediacaran-early Cambrian (~635-520 Ma) was an interval of immense global change with fundamental state shifts occurring in the bio-cryo- and atmosphere. Such changes included the abrupt appearance and rapid diversification of modern metazoan life (the Ediacaran fauna and Cambrian explosion), the end of protracted, global-scale glaciations (Snowball Earth), the rise of atmospheric oxygen to present-day levels, and the perturbation of carbon isotopic records to extremes otherwise unknown to Earth history. Given the immensity and abruptness of those changes, they are clearly essential to an understanding of the development of life, the history of climatic change and the evolution of the oxygen and carbon cycles. Accordingly, great effort has been dedicated to acquiring detailed temporal records to investigate those changes through time, but we still lack a robust paleogeographic framework to study them in space. This is because paleomagnetic datawhich are used to determine the ancient positions of continentsexhibit aberrant behaviour at this time, the meaning of which is unknown. Four alternative hypotheses have been formulated to explain them: 1) rapid rotations of the entire solid Earth (true polar wander), 2) an unstable magnetic field, 3) pervasive data corruption, or 4) ultra-fast plate motion. Each of these hypotheses has far-reaching implications: Hypotheses 1, 2 & 4 reflect dramatic non-uniformitarian processes that would defy our understanding of geodynamics, whereas hypothesis 3 poses grave challenges to the interpretation of paleomagnetic data in Precambrian time. My vision with EPIC is to investigate and identify the origin(s) of the aberrant paleomagnetic data of this age, and to use that knowledge to directly reconstruct Ediacaran-early Cambrian paleogeog
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Sustainable Synthesis of Amides' (SUSAMIDE) targeting Horizon 2020.

assistant: **Abstract**

Despite the ubiquity of the amide group, its synthesis is not always straightforward and the existing methods for amide formation score badly from the perspectives of economy and sustainability.  This proposal aims to develop unprecedented methodology for amide synthesis, allowing one to access “challenging” representatives. Two routes are proposed to mitigate risk and to provide complementarity. The objective of the proposal is twofold: 1) to expand the available chemical space (allowing one to synthesize challenging amides previously considered inaccessible via library synthesis with existing methods) and 2) to substitute existing syntheses with better ones (delivering higher yields without using toxic reagents and minimizing waste). Achieving these two objectives will have an impact on the discovery of new molecular entities and the improvement of production processes in the fine chemicals sector. The power of the new methodology will be demonstrated on the synthesis of selected real-life examples, APIs (Active Pharmaceutical Ingredients).