RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Papyri and LAtin Texts: INsights and Updated Methodologies. Towards a philological, literary, and historical approach to Latin papyri' (PLATINUM), addressing dissemination and exploitation.

assistant: **Impact**

The aim of PLATINUM is to scrutinize Latin texts on papyrus from several points of view in order to highlight their substantial contribution to our knowledge of innovations in ancient Roman literature, language, history, and society, especially in the multilingual and multicultural contexts of the Eastern part of the Empire between the 1st century B.C. and 8th century A.D. The first phase of the project will consist in assembling, updating and publishing critical editions, in order to present a new and more accurate corpus of Latin papyri on an easily accessible online platform. The second phase will be focused on providing the texts with a specific, pluridisciplinary commentary that gives new insights on Roman culture.Coming mainly from Egypt and other Roman provinces (as well as Herculaneum and Ravenna), Latin papyri deserve more scholarly attention not only from papyrologists and paleographers, but also from scholars of Latin language, as well as intellectual and cultural historians of Rome. Latin papyri, tablets, and ostraka (potsherds) are constantly increasing in number through archaeological discoveries. Because they are so rare, they are even more valuable than the Greek papyri, which have garnered much attention. The Latin papyri have hitherto represented a border-line field of study that has not been fully exploited either by papyrologists or by scholars of Latin literature. Moreover, the obsolete bibliography and the considerable number of unpublished texts make the study of Latin papyri (and bilingual Latin-Greek, Latin-Coptic, Latin-Punic texts) - whether literary (e.g. Cicero, Vergil, law), paraliterary (grammar, medicine, magic), or documentary (letters, official registers, receipts) – a pioneering and challenging task. A more through study will reveal th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Use of reverse genetics to study insecticide resistance in the malaria vector, Anopheles gambiae' (2002-2006).

assistant: **Innovation**

Malaria is a devastating parasitic disease transmitted by Anopheles mosquitoes. All national malaria control programmes rely extensively on a limited number of insecticides to reduce transmission of this disease but the efficacy of these control measures is being reduced by insecticide resistance in the mosquito vectors.The applicant has identified strong candidate genes in Anopheles gambiae, the major malaria vector in Africa, that are predicted to confer resistance to two of the most widely used classes of insecticides. These genes are over-expressed in resistant mosquits and encode enzymes that detoxify the insecticides. Techniques to both over-express and silence genes in Anopheles mosquitoes have been developed by members of the host laboratory.By using these methods we will determine whether over-expression of our candidate genes is both necessary and sufficient to cause insecticide resistance in laboratory strains of A. gambiae. Definitive proof of the role of a particular enzyme in conferring insecticide resistance has never been obtained for medically important insects and yet such information is vital if plans to reverse resistance by developing novel insecticide formulations that block resistance mechanisms are to succeed.The generation of transgencic Anopheles mosquitoes is technically challenging and have only been achieved by a handful of laboratories worldwide. Dr. Catteruccia and her colleagues are pioneers in this field and hence undertaking this project in the proposed host laboratory will maximise the chances of success.The applicant is extremely well qualified to pursue this ambitious proposal having over 10 years of practical experience in the molecular biology of insecticide resistance. The training in transgenic technology that she w ill receive w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Development of Integrated Web-Based Land Decision Support System Aiming Towards the Implementation of Policies for Agriculture and Environment'.

assistant: **Concept**

The objective of LANDSUPPORT is the construction of a web-based smart geoSpatial Decision Support System (S-DSS), which shall provide a powerful set of tools devoted to (i) support sustainable agriculture/forestry, (ii) evaluate trade-off between land uses (including spatial planning) and (iii) contribute to implementation, impact and delivery of about 20 European land policies and also selected 2030 UN Sustainable Development Goals including climate change resilience goals and the key SDG 15.3 “achieving a land degradation-neutral world”. This objective is achieved by the integration of already existing databases (interoperability) at different scales with the development of high performance modelling engines simulating agriculture & forestry (e.g.crop growth), land degradation and environmental issues (e.g.fate of pollutants, ecosystem services). All the above, including their validation by remote sensed data will be ensured by a technology at the state of art for the developing environment (i.e.COMPSs), high-performing computing (e.g.GPU) and massive raster data management (e.g.RASDAMAN). LANDSUPPORT will be applied at four geographic scales: EU; 3 Nations (Italy, Hungary, Austria); 2 European Regions in IT and HU; 3 pilot sites in AU, IT, HU; and 2 pilot sites in Tunisia and Malaysia. By doing that, LANDSUPPORT will reconcile grand agriculture/environmental sustainability policy ambitions with operational reality as required by RUR-03-2017 call such as the evaluation of “land use trade-offs” and “incentivizing real actions/behaviour/investments”; all requiring activities at detailed spatial scale. LANDSUPPORT fits with the priorities of this work programme, as LANDSUPPORT S-DSS is (i) scientific and technology innovation as driver for rural development, (ii) a frame
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Through the eye of a mosquito: theoretical modelling of vector-borne zoonotic pathogens', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The spillover of wildlife diseases into humans is increasing, and represents one of the biggest global health challenges we are facing today. Many zoonoses are transmitted by vectors (i.e. mosquitos) and had a large number of vertebrates as reservoirs. Thus, to reduce its impact on humans, it is essential to understand the factors that promote or inhibite spillover into human populations. Thus, it is necessary to consider the epidemiology of the pathogens both in vertebrate and vector communities. Technically, this requires an integration of community and disease ecology into a single mathematical framework, which explicitly considers vectors and hosts as distinct species, with different potential for pathogen amplification and contact rates. While mechanistic models exploring vector population dynamics have a long history, multihost-multivector model have not adequately integrated heterogeneity in host-vector interactions, despite their obvious importance. Here, I will study the role of vector species with distinct behaviour and ecological requirements in shaping the complex pathogen transmission dynamics, and ultimately determining the spillover, persistance or extinction of pathogens. My objectives are at the interface of theoretical and empirical research: 1) I use a rich data set to characterize the web of interactions between vectors and hosts, 2) I extend existing theory to explicitly consider vectors as distinct species and 3) I then study the role that behavioural heterogeneity has in shaping the larder web, and ultimately determining the risk of spilling over vs. disease extinction. Because of there is an urgent need to combine theory with data, I will also create an open source webpage where all the details of my work will be regularly updated in order to set
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Programmable bacterial catalysts' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

The project aims at constructing of a functioning, streamlined bacterial cell devoid of most of its genome and endowed with a series of highly coordinated, newly assembled genetic circuits for the biotransformation of a range of chloroaromatics into high added value compounds and that would include (although not necessarily in this order or all together) circuits for synchronized behaviour, noise minimisation and/or low-temperature biocatalysis and, in addition, amenable to directed, accelerated evolution so that the function of each or some of the individual circuits can be optimised. This will be tested for the production of high added value compounds from chloroaromatics in bioreactors. By achieving such constructs as a proof-of-principle, it is aimed at establishing a solid, rational framework for the engineering of cells performing effectively and efficiently specific functions of biotechnological, environmental or medical interest. This encompasses the production of series of different, versatile circuits and corresponding components that can be used as building blocks in circuit engineering. The proposed workflow includes several work packages, each of which intertwining mathematical modelling with wet-lab experimental work as an integral module. PROBACTYS is a pioneering, concerted European effort towards the development of a Synthetic Biology framework and with a strong focus on the translation of emerging knowledge in biology, engineering and information technology to the development of new processes of biotechnological relevance.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Development of an improved vaccine against contagious bovine pleuropneumonia' to be submitted under Fifth Framework.

assistant: **Abstract**

Contagious bovine pleuropneumonia (CBPP) represents a major constraint to cattle rising in Africa. Its eradication is hampered by the low efficacy of the available vaccines. Therefore, development of an improved vaccine is the objective of this project. To achieve this aim, the protective immune response elicited in CBPP-recovered cattle and the pathogen components involved, will be characterised. The mechanisms and virulence factors responsible for pathogen/host cell interactions will be assessed. In vitro models for testing the safety of the selected immunogens will be developed. This study will define the cell subsets, cytokines and immunoglobulins involved in protection and, safe and efficient immunogens as vaccine candidates. These data will determine the appropriate vaccine strategies against CBPP.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Digital AV Media Damage Prevention and Repair' in the context of a Seventh Framework call.

assistant: **Objectives**

Digital audiovisual (AV) content is everywhere: film, television and online media; personal content from cameras and phones; and content from environmental monitoring, corporate training, surveillance and call recording to name but a few. Retention includes content reuse, regulatory compliance, and archive monetisation – each with differing needs for content quality, safety, storage, access and budget. But there is a common challenge: how to keep AV content usable in the face of adversity: obsolescence, media degradation, and failures in the very people, processes and systems designed to keep this content safe.We will research how to structure, store, monitor, repair and improve digital AV content in a way that balances long-term costs, risks of loss, and content quality. We target digital video tape, which for many remains the de-facto form of born-digital content, as well as the rapid adoption of AV as files in IT systems. A risk management approach is taken for analysing the causes of loss, not just from storage technology, but also from the systems that surround storage, and how this loss impacts the ability to use digital AV now and in the future. Scalable tools for damage detection, repair, and quality improvement are then added to deliver complete digital AV quality assurance over time. Calibration, testing, evaluation and demonstration by archive and industrial partners using real-world data ensures high quality project results.The consortium includes: a broadcaster and national audiovisual archive, both with experience of R&D in digital preservation; two industrials on the supply-side providing media migration, digital restoration, and quality analysis; and two research partners with long histories in digital audiovisual content analysis, risk management, and s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Novel mesoscale magnetic arrays and devices' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Heavy ion irradiation of suitable thin films has recently been demonstrated to be a very promising technique for engineeling mesoscopic magnetic systems. The aims of the research project are: a) to engineer novel mesoscopic magnetic systems by ion beam irradiation, b) to study their magnetic properties (anisotropy, coercivity mechanisms, magnetoresistance). The mesoscopic systems will be fablicated by irradiating multilayers of Al/Mn prepared by sputter deposition. Subsequent ion irradiation will induce interdiffusion of A1 and Mn leading to the formation, along the ion paths, ol AlMn fenomagnetic nanocolumns embedded in the non-magnetic metallic matrix constituted by the Al/Mn multilayers. The morphology of the magnetic nanoparticles will be controlled by varying irradiation parameters.The inter-particle distance and hence the magnetostatic interactions can be controlled by varying the ion beam flux. Subsequent magnetic and structural characterization will be performed in order to study the influence of the obtained microstructures on the magnetostatic interactions and then to understand the influence of magnetostatic interactions on anisotropy, magnetization reversal processes and magnetoresistance. The production of microstructure controlled samples is a first step towards the production of new magnetic materials with engineered extrinsic magnetic properties which may ultimately be harnessed in the form of technological devices.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Production of superior meat analogues by bridging the benefits of plant proteins and mycelium protein biomass produced from circular substrates' in the context of a Horizon Europe call.

assistant: **Objectives**

PLANTOMYC is a transformative initiative aiming to reshape the landscape of the alternative protein sector. It aims to bridge the versatile benefits of plant-based proteins with the functional and organoleptic (taste, aroma, texture) advantages of mycelial protein biomass (MPB) and develop innovative minimally processed hybrid meat analogues that are both healthy, and tasty. The project promotes sustainability by upcycling underutilized circular substrates such as starch rich pea protein by-product, and brewers spent grains to produce MPB by submerged fermentation (SmF) and solid-state fermentation (SSF), respectively. Envisioning a near-zero waste process design, PLANTOMYC proposes converting the broth from SmF into a Gamma-aminobutyric acid (GABA) enriched beverage and / or a flavorful bouillon. Adopting a multi-actor approach, the project addresses challenges related to consumer preferences, technological scaling, and regulatory requirements. Notably, the impact of PLANTOMYC’s product prototypes on nutritional, functional (gut health & metabolic syndrome), techno-functional, and sensory properties will be assessed thoroughly. Moreover, to advance PLANTOMYC’s TRL, we perform a comprehensive impact assessment for the adoption of these products, utilizing our consortium’s industrial end-users. PLANTOMYC will significantly increase the competitiveness of European alternative protein initiatives. It will accelerate the sector by offering an open-access knowledge platform, introducing new production concepts for hybrid meat analogues, increasing resource independence and efficiency, providing new market opportunities for industrial partners like Millow, BRØL, and Lantmännen, increasing the affordability of alternative proteins, and reducing the environmental footprint of p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'New tools for controlling human nk cells functions and cd40-cd40l interaction in nk-tumor cell recognition' (1994-1998).

assistant: **Innovation**

Research objectives ant content Our recent finding indicate that CD40-CD40L represent an important NK cytotoxicity activation pathway. One of the objectives of this proposal is to investigate the possibility that CD40 can be expressed on tumor cells and whether it can be recognized by autologous NK cells. The second objective is to generate new monoclonal antibodies panel to NK cells (NKmAbs) able to tune NK cell programs not only related to cytotoxicity function but also cytokine production. Training content (objective. benefit and expected impact) The benefit for the proponent is to improve capability to develop new monoclonal antibodies, and strenghted his knowledge in tumor immunology. The expected impact is to make available, a complete reagent panel able to give selective tuning of NK function, moreover the importance of the CD40-CD40L activatory pathway will be determined in a tumor cell system. Links with industry / industrial relevance (22) The project will be carried out in collaboration with the MABTECH AB (Stockholm), the specific NK mAbs can be patented.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Towards a social neuroscience of health-related decision-making' (SOCIALCRAVING) under Horizon Europe.

assistant: **Objectives**

Social relationships have important effects on health and disease. Our interactions with others, feelings of social isolation versus connection, and perceived social norms influence behavior, physiology, and even mortality. Yet, an ongoing challenge is to understand the brain mechanisms underlying social context effects on human health, which could ultimately enable us to use neuroimaging to predict psychosocial risk factors and individual vulnerability to unhealthy lifestyle. I propose to address this challenge, by testing how social norms and social relationships influence food and alcohol craving and health-related decision-making. Paralleling my recently developed brain signature of food and drug craving, I predict that I can develop a brain signature of social craving—our unfulfilled need for social contact—using fMRI and machine learning, and that responses of this signature are associated with increased susceptibility to social context effects on decision-making and health. Work package (WP)1 will test the effects of social influence on food craving, drink craving, and delay discounting, and whether social influence effects generalize across tasks. WP2 will test whether and how social rejection versus connection increases food and drink craving, delay discounting, and social craving. WP3 will use machine-learning to develop a new neurophysiological signature of social craving and use data from all WPs to investigate whether responses of this social craving signature are associated with 1) susceptibility to social influence, 2) social rejection effects on decision-making, and 3) aggregate measures of lifestyle, mental, and physical health. By uncovering the brain bases of social context effects, the SOCIALCRAVING project will transform our understanding of the neu