RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Body Interact - Training skills environment to improve patient safety and medical education'.

assistant: **Concept**

Body InteractTM is an immersive medical “flight” simulator that allows healthcare professionals (HCPs) to experience responsive real clinical cases in virtual environments. HCPs will see its skills and competences improved, as this multi-platform displays a great diversity of real scenarios, based on a scientific algorithm, providing better training and thus reducing costly and sometimes fatal errors. Simulation training is essential to de-risking complex interventions with lives at stake. Every year in Europe, an estimated 8 to 12% of patients admitted in hospital suffer from adverse events whilst receiving healthcare . Body Interact provides better training than conventional training solutions, such CAE Healthcare and Laerdal, that are focused only on physical non-responsive tools and do not provide enough accurate simulation. Body Interact Software provides to HCPs a simulation tool with a scientific algorithm that creates a virtual responsive patient, based on the real physicochemical reactions of the human body, enabling users to download specific clinical cases to solve, based on real life scientific documented pathologies. The main objectives of Phase 1 are to develop relevant business cases in healthcare sector with big players, such as pharmaceutical companies, University Hospitals, Hospitals and Healthcare Associations, to install pilots at medical schools and training facilities in strategic countries (Europe, Canada and U.S.A), to develop first trauma, paediatrics and chronical diseases clinical cases, and new clinical cases with the support of its scientific and endorsement partners to follow international guidelines.The vision of Take the Wind for Body Interact Platform is to improve both patient care and the efficiency of healthcare delivery, by empower H
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'In situ analysis of chaperone mediated protein folding and stability' under Horizon Europe.

assistant: **Concept**

Molecular chaperones mediate protein folding and conformational maintenance. Failure of these fundamental cellular functions results in a breakdown of protein homeostasis (proteostasis) and facilitates the manifestation of diseases associated with protein aggregation. Much progress has been made in understanding the mechanisms of individual chaperone systems, such as the Hsp70s and the chaperonins, based on analyses in vitro. How these machineries function in the intact cell is not well understood, however. The goal of this proposal is to observe and characterize the dynamic action of the major chaperone systems and their interplay in intact cells in real time.Using live cell single molecule imaging combined with biochemical analyses, proteomic profiling, and genetic screening, we will address the following questions:i) How does the chaperone machinery assist protein chains during and after translation to achieve folding and assembly? We will develop single particle tracking to monitor the chaperone engagement of nascent chains in situ in mammalian cells.ii) How is the conformational stability of chaperone clients assessed, maintained and triaged in healthy cells and in cells burdened with pathological aggregates? We will track the interactions of metastable proteins with chaperones and proteolytic machinery.iii) What is the efficiency of protein folding across the proteome under normal conditions and in chaperone-deficient cells? Pulse proteolysis/mass spectrometry will be developed to analyze the folding of nascent polypeptides and will be scaled to analyze the entire proteome of different cell types. By depleting specific proteostasis components we will explore the capacity of the chaperone network for compensatory rewiring and identify vulnerable proteins with an ob
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'High resolution X-ray imaging for improved detection and diagnosis of breast cancer' under Sixth Framework.

assistant: **Concept**

Breast cancer is currently the most common cause of death for women below seventy years of age and currently over 100 million European women are screened every year for early detection through mammography.The objective of the proposal is to increase the efficiency in detection and diagnosis of breast cancer and thus to decrease the mortality in breast cancer. To achieve this we will develop a novel imaging method based on recent results in the research fields of nano-technology, x-ray optics, detector technology and integrated electronics. The new modality will be designed by leading European industry and SMEs in these areas and develop the only commercially available European detector platform for digital mammography today into a leading technology platform for tomorrow. The novel method will provide significantly increased contrast and spatial resolution compared to current state-of-the art breast imaging through elimination of noise from electronics as well as from overlapping tissue and by way of utilizing the signal more efficiently through fast single photon counting parallel processing integrated circuits.To make sure that the project target the right issues in breast imaging experienced mammography doctors from several European breast imaging centres are involved in the project and they will also test and evaluate the new imaging system and compare it to current state-of-art mammography as well as ultrasound and MR imaging of the breast. The clinical trials will involve an enriched population of symptomatic women and the potential impact on European screening for and diagnosis of breast cancer will be estimated from the results. In summary the project will have significant impact on European healthcare and make European industry a leader in the area of breast im
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'High-resolution image-based computational inner ear modelling for surgical planning of cochlear implantation' (HEAR-EU) targeting Seventh Framework.

assistant: **Abstract**

Cochlear implantation is a surgical procedure that aims to overcome hearing loss by direct electrical stimulation of the spiral ganglion cells in the cochlea of the inner ear. The surgical scenario of implantation surgery is very complex. It requires high clinical expertise in order to 1) efficiently access the surgical site, the cochlea, localize nearby critical structures (e.g. facial nerve) and 2) optimize the position of the implantable device (electrode array) inside the cochlea. Furthermore, there is a vast anatomical variability amongst patients. This makes individual optimal fitting an extremely difficult task and strongly influences the success of the surgery and subsequently hearing restoration.We hypothesize that a comprehensive understanding of the shape variability of the middle and inner ear among patients will enable the design improvement of hearing implants, and will be of assistance during surgical planning. Consequently, the aim of this project is: 1) to develop a novel high-resolution high-energy microCT device to obtain detailed images of the middle and inner ear, even in the presence of metallic implants, 2) to build a model of the shape variability of the middle and inner ear from high-resolution images, also incorporating functional information, 3) to build a computer-assisted patient-specific preoperative planning system, and 4) to improve the design of cochlear implant (CI) electrode arrays and associated insertion tools using a population-based optimization framework. All objectives revolve around the criteria of minimizing invasiveness, insertion-induced trauma and enhanced functional outcome through patient-specific frequency mapping.The consortium is composed of two research-intensive SMEs, one university hospital, two universities, and a l
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'FUNCTIONING OF THE LOCAL PRODUCTION SYSTEMS IN THE CONDITIONS OF ECONOMIC CRISIS (COMPARATIVE ANALYSIS AND BENCHMARKING FOR THE EU AND BEYOND)' (FOLPSEC), addressing dissemination and exploitation.

assistant: **Impact**

Local Production Systems (LPS) could be characterized in different ways, thus their definition is neither simple, nor unified task. One of the most popular definitions is the one given by Local Production & Innovation Systems Research Network – “territorial union of economic, political and social actors, whose efforts are focused on a specific group of interrelated activities”. LPS have strong impact on regional development. To this end, LPS establishment and functioning in the EU member states and in third countries are subject to intensive research and discussed in different strategic documents. As of the ‘90s of the last century LPS in EU(15) are in a process of constant development while in the new EU MS and in third countries they are still in the initial phase. The world economic and financial crisis further attracted the attention of the researchers to LPS establishment and functioning. FOLPSEC aims at deepening the theoretical studies on LPS and to encourage their practical implementation as an approach for world crisis overcoming. It has the following objectives:1. To exchange knowledge on research approaches in studying LPS and to make recommendations for EU good practices implementation in the conditions of economic crisis;2. To share partners’ results on LPS functioning concerning economical and social regional acceleration and regional disparities relative overcoming;3. To make use of knowledge gained and good practices identified for research and teaching purposes at all partner institutions;4. To establish long-term research cooperation between EU and Third countries and to strengthen research partnerships.In order to achieve our goal we created a network of partner institutions located in EU(27) member states (Bulgaria, Poland and Slovakia) and in Eligib
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'A test of Bayesian decision analysis and the implications for conservation' under Seventh Framework.

assistant: **Concept**

Conservation biologists work hard to prevent species extinction and rely on robust quantitative methods to achieve these ends. Decision frameworks allow assessment of alternate management strategies for threatened species, and may rely on simulated population models where data are unavailable or unreliable. Bayesian inference can be used to inform decision frameworks, and has come to the attention of many biologists because the Baye’s approach allows expert opinion or informed priors to update models where data are otherwise unavailable. These require further testing, and this is often difficult where data for long-lived species are difficult to collect. Here I will use short-lived soil mite (Sancassania berlesei) populations in a laboratory environment to replicate subpopulations critically endangered black rhino (Diceros bicornis). By confronting Bayesian models with real data, I hope to test the robustness of priors in Bayesian models, compare this approach to more traditional frequentist approaches and gain insight into the usefulness of Bayesian in decision-making. I propose to take this further and use the knowledge gained to develop and configure a decision making framework for the management of black rhino populations across southern Africa.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Liverpool mathematics international training site' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

The Department of Mathematical Sciences of the University of Liverpool invites applications for short-term postgraduate fellowships (between 3 and 12 months) to be held at the Marie Curie Training Site Liverpool Mathematics International Training Site". During the period 2002-2005 approximately 12 such fellowships will be awarded. Training will be provided in the following areas: Algebraic geometry, especially birational geometry, K3 surfaces and Calabi- Yau manifolds, module of vector bundles and arithmetic geometry. Kac-Moody algebras. Singularity theory, especially geometry and topology of singularities, symplectic and contact geometry, finite-type invariants and applications to computer vision. Knot theory, especially braids, knot invariants and associated algebras. Every candidate must be a citizen of a EU country (other than the UK) or an associated state, or be able to provide proof of having resided in a member state for at least the last five years. A candidate must also be registered for a Ph.D.-level degree in a country other than the UK and in a subject similar to those of the Site. Each fellow will receive a grant of 1200 euros per month for the duration of his/her stay in Liverpool and the costs of one return trip between his/her present country of activity and Liverpool Further information may be obtained from the coordinator, Dr. Peter Newstead (e-mail: newstead@liv.ac.uk, tel.: +44151 794 4040) or from the webpage: http://www.liv.ac.uk/Maths/"
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Infrastructure for Protein Production Platforms' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The most important prerequisite and challenge in structural biology research at the atomic level by any method is the availability of sufficiently large amounts of highly purified functional proteins due to the increasing size and complexity of target proteins or protein complexes to be analyzed. Heterologous expression in bacteria, yeast, insect, or mammalian cells combined with many attempts involving different DNA constructs that result in a large variety of protein variants is instrumental to obtain sufficiently high yields. This means high-throughput methods employing robotics and specialized infrastructure are essential to efficiently reach the state of obtaining functional protein and/or crystals for X-ray structure determination. PCUBE ('protein production platform') combines existing infrastructures and know-how of leading European laboratories in bacterial, eukaryotic expression of proteins, in high-throughput crystallization and in libraries design for the effective production and crystallization of macromolecules. The program aims at offering these various state-of-the-art platforms to research groups from EC member and associated states for the efficient production of proteins for their structural studies. Each infrastructure will offer defined procedures for applying for transnational access. Scientific selection committees will give priorities to applications by scientific criteria of excellence only. Researchers from the different sites offering infrastructure are combining efforts to improve the methods in the various areas by collaborating by joint research activities. These include the improvement of the automation for synthesising DNA constructs, for parallel expression, for improved libraries, for the efficient selection of affinity molecules from l
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Colloidal Quantum Dot Quantum Optics' in the context of a Horizon 2020 call.

assistant: **Objectives**

Colloidal semiconductor nanocrystals have already found significant use in various arenas, including bioimaging, displays, lighting, photovoltaics and catalysis. Here we aim to harness the extremely broad synthetic toolbox of colloidal semiconductor quantum dots in order to utilize them as unique sources of quantum states of light, extending well beyond the present attempts to use them as single photon sources. By tailoring the shape, size, composition and the organic ligand layer of quantum dots, rods and platelets, we propose their use as sources exhibiting a deterministic number of emitted photons upon saturated excitation and as tunable sources of correlated and entangled photon pairs. The versatility afforded in their fabrication by colloidal synthesis, rather than by epitaxial growth, presents a potential pathway to overcome some of the significant limitations of present-day solid state sources of nonclassical light, including color tunability, fidelity and ease of assembly into devices.This program is a concerted effort both on colloidal synthesis of complex multicomponent semiconductor nanocrystals and on cutting edge photophysical studies at the single nanocrystal level. This should enable new types of emitters of nonclassical light, as well as provide a platform for the implementation of recently suggested schemes in quantum optics which have never been experimentally demonstrated. These include room temperature sources of exactly two (or more) photons, correlated photon pairs from quantum dot molecules and entanglement based on time reordering. Fulfilling the optical and material requirements from this type of system, including photostability, control of carrier-carrier interactions, and a large quantum yield, will inevitably reveal some of the fundamental pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Monolithic integration of light emitting devices with SI ICS using conformal epitaxy', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The global objectives and anticipated results of the project are:1 To prove the efficiency of the conformal growth technique to integrate monolithically high quality GaAs-based light emitting devices on silicon.2 To examine and improve the compatibility between the conformal growth technique and the standard silicon CMOS processing, the conservation of performances of the silicon ICs being a main goal.3 In case of partial compatibility, to evaluate accurately the required modifications on silicon ICs design and technology in order to decide on further industrial development of this integration technique.This project deals principally with the realisation of the building block of future optically interconnected systems, i.e. GaAs light emitting devices integrated with their silicon drivers. A monolithic integration method, based on the use of the new conformal epitaxy technique, will be developed.In a first two-year step, the monolithic integration will be studied and validated through the completion of three works, leading to a LED + driver demonstrator:- Silicon drivers compatible with the requirements of conformal epitaxy (specific geometry, eventually misoriented substrates, aluminium metallisations postponed after III-V growth) will be designed, processed, and their performances accurately evaluated before and after the integration process.- High quality GaAs layers will be grown on these drivers using conformal epitaxy. The conformal procedure will be improved in order to increase its compatibility with the technology and high performances of silicon ICs. Special efforts will be devoted to decrease the presently used substrate misorientation and temperatures of substrate preparation and growth.- These layers will then be used as substrates on which the subsequent g
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Transport Research Arena 2026: Budapest' to be submitted under Horizon Europe.

assistant: **Abstract**

The TRA2026 project aims to support the organisation of the TRA conference in Budapest in 2026 and deliver the related competitions. This proposal aligns with the specified criteria of the call, namely:•It addresses the expected outcomes, including enhanced visibility of the transport sector, contributions to advancing knowledge, improved cooperation opportunities, as well as increased attractiveness of transport-related studies, as well as recognition of outstanding achievements in this field.•It features a partnership representing the host country and city authorities, as well as the academic and professional realm, with a strong international reach. The proposal involves partners with experience across all transport modes and cross-modal themes, as well as in organising past TRA conferences and researcher competitions. A member state responsible for the Council of the European Union in 2026 is also represented in the consortium.•The partners will work together and with relevant stakeholders, drawing on the traditions of previous TRA editions to bring together key actors in the transport sector to find joint solutions for current and upcoming transport-related challenges.


**Keywords:** Transport Research Arena, Budapest