RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Service Assurance for Large Social Acceptance of Photovoltaic Stand Alone and Grid Connected Systems' (PV-SALSA), addressing dissemination and exploitation.

assistant: **Impact**

The main objectives of the project is to improve social acceptance of RES by:-Cost reduction of PV systems thanks to wholesale orders , standardisations and cost effective monitoring through a transnational pool of resource;- Taking in account the point of view of final users small size stand - alone or grid - connected PV systems as a major issue for final users q-small size stand alob-ne or grid connected pv system as major issue for mass development of pv in two European countries with very different legal and economical framework , Spain and France;- Promoting energy efficiency and demand side management anong PV final users;- Improvement of economic and -social conditions in ruralm areas by rural electrification -Reduction of co2 emission by PV generation connected to the grid;- Improvement reduction of deforestation by grid extension in Mediterranean fragile forests.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Optical fibre biomimetic sensors based on Lossy Mode Resonances with Molecularly Imprinted Polymers' (OFBioSens-MIP).

assistant: **Concept**

This project aims to design and test a low-cost, highly sensitive and selective optical fibre sensor for testosterone, based on testosterone-recognising molecularly imprinted polymers (MIPs) combined with lossy mode resonance (LMR) structures.Optical fibre (OF) sensing has attracted great attention in the last years due to the benefits that it offers compared to traditional electronic sensors. Some of these benefits are small size, biocompatibility and immunity to electromagnetic fields. Among all OF sensors topologies, those based on spectral techniques are the most sensitive and robust. Specifically, OF sensors based on electromagnetic resonances - i. e., surface plasmon resonance (SPR) or LMR - have become a standard in the last years due to their high performance.The exciting potential of LMR-based sensors is combined in this proposal with bio-mimetic polymer technology in order to develop a new generation of sensors with defined chemical specificity. With this aim, the following specific objectives have been established:- To design and optimise the MIP formulations for the binding of testosterone while supporting and enhancing LMRs.- To characterise the properties of the MIPs regarding their structure, orientation and physical and chemical stability.- To study and optimise different deposition methods to coat the OF device with the selected polymer in order to obtain a testosterone sensor.- To model the OF sensor in order to predict its features and the optimum configuration.- To study the sensors’ response to different concentrations of testosterone in samples, evaluating its sensitivity, stability and selectivity.- To develop a small, light and low-cost system for the sensor in order to explore its commercial potential.The methodology and results obtained from th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'The genetic basis of division of labor: testing the “reproductive groundplan hypothesis” in ants'.

assistant: **Innovation**

The evolution and maintenance of cooperation in the face of inevitable conflicts, is regarded as one of the major questions in biology today. Answering this question requires understanding both the proximate basis of cooperative behavior and its comparative biology, but studies integrating experimental and comparative approaches are rare. Social insects are one of the pinnacles of sociality, with societies characterized by reproductive division of labour, one of the major evolutionary transitions in biological organization. While most of the research in the last century has focused on the ultimate reasons favoring cooperation, the methodological advances during the last decade has provided the tools necessary to study the genetic basis of cooperation directly. The “reproductive groundplan hypothesis” (RPGH) has emerged as one potentially powerful explanation for the proximate mechanisms for the evolution of eusociality. It postulates that conserved gene networks, which underlie the reproductive physiology and behavior of solitary insects, were co-opted and modified during the evolution of eusocial insects to generate worker division of labor. This hypothesis is potentially of fundamental and far-reaching importance for our understanding of the mechanistic basis by which eusociality evolved, but empirical evidence in support of the hypothesis is still limited to only a few species. This project will combine large scale phylogenetic tests of the RPGH, with endocrinology, state of the art molecular techniques (RNA interference) and classic behavioral analysis, to investigate if the RPGH applies to ants and therefore represents a general explanatory framework for the evolution of division of labour in social insects. The training in three cutting-edge sets of techniques wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Evaluation of the application of neural networks to distributed optical fibre sensors'.

assistant: **Innovation**

Research objectives and content The proposed project is a feasibility study into the application of neural networks to novel multi-point on distributed optical fibre sensors. Distributed optical fibre sensors produce complex signals at the point of signal detection. This complexity is cross modulation due to interference from parameters other than those being measured. A classical example of this is pressure changes affecting shifts in wavelength of the detected light in distributed optical fibre temperature sensors. Such effects can be minimised using wavelength referencing, but this is not always the optimum solution and can be expensive when used in conjunction with optical time domain reflectometry (OTDR). It is the intention of this project to investigate data from a previously developed sensor of relatively simple construction. Such an example is is one to detect the presence contamination of water supplies at multiple points in a system and requires the e application of OTDR techniques to detect the point on a long loop of fibre at which the contamination has occurred Effects other than fouling at a single point will then be modelled into the system e.g. change in coloration of the water (which itself is possibly a source of contamination), damage to the fibre e.g. microcracking, ageing effects of sources and detectors. It is envisaged that such extraneous effects will give rise to optical signals with characteristic temporal signatures and that the neural network may be trained to recognise these characteristic changes. The inclusion of neural network software requires relatively modest computing power and thus may easily be adapted to existing sensor systems which utilise PCs or dedicated computers or microcontrollers for the complex signal processing involved
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Anchored Muscle cELls for IncontinencE' (AMELIE).

assistant: **Innovation**

Faecal incontinence (FI) is a common condition affecting ~67 million people in Europe, seriously impairing living and productivity of affected individuals and their families. Women with FI arising from childbirth injury may benefit from regenerative medicine using autologous skeletal muscle derived cells (ASMDC) to restore function of damaged sphincter muscle. However, progress is hindered by sub-optimal manufacturing and delivery techniques contributing to inconsistent results. AMELIE proposes an innovative approach that uses ASMDC attached to implantable microcarriers that will enable delivery of a higher number of viable ASMDC into the damaged sphincter muscle, increasing the likelihood of cell engraftment, regeneration of muscle and improved continence. To achieve this, AMELIE will develop bespoke implantable microcarriers suitable for clinical use; establish robust bioprocessing for manufacture of the cell-microcarrier combination; and for the first time, robustly test, in a clinical study, the principle that delivery of ASMDC in an anchored, natural state, are safe and provide more effective and consistent treatment. AMELIE comprises a highly interdisciplinary, gender balanced, consortium of internationally recognised experts and key-opinion leaders with relevant experience from academia and industry across Europe in the fields of engineering (IST, UCL, NHSBT), biological sciences (NHSBT, UCL, IISFJD), and translational regenerative medicine (QMUL, MUG, AUH, AU, RUH, UHE, IISFJD, CVBF). BCR will lead dissemination activity and stakeholder interaction with patients and the public, healthcare professionals, industry and third party FI charities across Europe to establish reciprocal dialogue with people that will interact with the new technology throughout the lifeti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Earth Observation Value Adding Services – Earth Observation Design and Publishing Service'.

assistant: **Objectives**

The proposed project (hereafter: EO-VAS project) will RESHAPE Earth Observation Value Chain by BREAKING “DOWNSTREAM” component and significantly SIMPLIFYING development and delivery of Earth Observation Adding Value Services (hereafter: EO VAS).Project foundation is built around SINERGISE’s award-winning (2016 Copernicus Masters Award) Sentinel Hub Operational Prototype (world-first engine for archiving, processing and distribution of Sentinel data) and GEOVILLE’s extensive set of processing algorithms (applied in over 100 existent EO VAS).Main project delivery, EO-Toolset has an ambition to become:- First virtual market place for EO VAS, introducing completely NEW BUSSINESS MODEL in the area of EO services = model, benefiting all participants in EO value chain - from data providers, through service providers to end-users.- EO VAS innovation hub: fostering development of EO services, becoming a virtual meeting place for the exchange of new ideas and encouraging EO VAS experimenting - Virtual business incubator for emerging earth-observation oriented start-ups, that lack the means to commercialise their EO services by themselves. - Pre-processing engine for other EO domain services, helping them to reduce pre-processing costs and to turn their attention into domain expertise and higher quality of their products.EO-VAS will focus on the agriculture and non-life insurance as high revenue entry markets, with the entire optical EO space industry application domain field as revenue market. Conservative investment ROI turning point is 2022 with project’s 15-year’s Net present value of almost € 11,2 MIO, Internal rate of return of 46%. Importantly, due to the setup of EO-VAS enabling customer processing capacities, an significant economic benefit is expected to the entire EO ap
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Trancriptional control of dendritic arbors morphology in pathogeny and therapy of neuropsychiatric diseases' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Neuropsychiatric disorders affect 25% of the population sometime during their life. Aberrant dendritic arbors appear in mental disorders. Although the psychopathological mechanisms are not completely understood, it has been suggested that changes in gene expression contribute to the development and therapy. Several evidences, including the applicant own studies, suggest that misregulation of Sp4 transcription factor could be involved in the pathogenesis and therapy of affective disorders by controlling dendritic patterning. The applicant will explore the possibility that Sp4 and other transcriptional regulators might be altered in postmortem human brains of patients with mental disorders. This research pretends also to investigate the capability to regulate dendritic development by altered novel factors and psychotropic treatment.  This project we will test the hypothesis that mood stabilizer and antipsychotic drug leads to a physiological dendritic patterning, in part, through the stabilization/activation of Sp4 transcription factor which leads to changes in expression of genes important for the pathogenesis and therapy of neuropsichiatric disorders.  To address that hypothesis (a) we will study whether the levels of Sp4 transcription factor protein or other factors are altered in postmortem brain tissue from patients with schizophrenia or affective disorders. (b) We will perform a novel quantitative proteomic approach (SILAC) and gene expression arrays in postmortem brain of neuropsychiatric patients and whether the new hits module dendritic patterning. (c) And also, we will study the effect of mood stabilizers and antipsychotics on dendritic morphology by Sp4-dependent mechanism. These studies will give a new insight in the transcriptional programs controlled by lith
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Sheltered load at the MHC'.

assistant: **Innovation**

The accumulation of deleterious mutations and their subsequent effects on fitness play an important role in genome evolution. The mutational load is, however, not distributed evenly across the genome. In particular, genomic regions under strong balancing selection, as well as areas with little recombination are prone to accumulate mutations. In such genomic regions natural selection cannot easily purge the recessive deleterious mutations because they become rarely expressed in homozygote condition, and hence, this mutational load has been dubbed a “sheltered load”. Both the Major Histocompatibility Complex (MHC) of vertebrates and S-locus of plants are thought to carry a large sheltered load which can have important implications for the evolution of both these gene families. However, these research communities have developed their research programmes and theories independently of one another. This proposal brings together both fields for the first time in a truly synergistic collaboration that will investigate several fundamental, and yet unaddressed questions in evolutionary genetics of multigene families. It combines the expertise of the Marie Curie Fellowship applicant (Dr Llaurens) on the evolution of self incompatibility in plants and that of Dr van Oosterhout (University of Hull, UK) on MHC evolution in guppies (Poecilia reticulata). This project aims to empirically characterise the sheltered load in the MHC of guppies by using high-throughput sequencing techniques in collaboration with Prof. Dreyer (Max Planck Institute, Germany). We will furthermore investigate the evolutionary and ecological implications of this MHC-linked sheltered load by using laboratory crosses and field experiments. The comparison between MHC and S-locus evolution will help us to elucidate
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'ULTRA-SOUND COMBINED WITH BIA AND GRAPHENE FET-ENHANCED WEARABLE SENSING FOR DECENTRAL HEALTH-MONITORING'.

assistant: **Innovation**

The prevalence of overweight among the European population is estimated to be near 50% and the prevalence of obesity around 16%. Monitoring obesity and overweight prevalence is important for assessing interventions aimed at preventing or reducing the burden of obesity and related medical risks and providing the tools for maintaining a healthier lifestyle. UltraSense project introduces the concept of a stretchable multi-sensing platform, as a wearable tool for body composition analysis and overall decentral health monitoring, fostering a sustainable and healthier lifestyle.The platform will comprise smart features, AI signal processing and advanced stretchable materials, enabling the efficient synergy of three compartments of sensors relying on different technologies:A. Ultra-sound compartment: delivering precise information about body composition and tissue thicknessB. Bioimpedance compartment: fast and reliable measuring of the percentage of fat, water and muscleC. G-FET biosensor compartment: Biomarker retrieval via sweating at atto-Molar sensitivity in miniaturized footprintThe wearable device will be validate in two use cases:1. The effect of sport on a healthier lifestyle: monitoring the overall health of people who exercise2. Early detection and continuous monitoring of metabolic syndrome.Ultra-Sense's data will be displayed to the user with consistency and reliability, so that medical advice can be sought.The green and circular material synthesis approaches of the project will reduce the related CO2 emissions by more than 70% from solvent processing. UltraSense will have a huge societal and economic impact: 700k devices will be sold annually already by 2032 for 105M€ of revenues reaching a 10% market share and associated with 20 new jobs. Millions of people will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Monitoring of fatigue damage in fibre-reinforced composites' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

Although being used for a longer time for fatigue resistant applications, the fatigue behavior of composites in fact is not well understood yet. Major differences with metals for example are: the early onset and growth of more or less widespread damage (from the first cycles on), as well as the associated gradual degradation of the stiffness properties (up to 30% and more). Simulation of damage growth and stiffness reduction is therefore quite different than for metals and adequate numerical tools are non-existent.The proposed project aims at studying the feasibility of monitoring the mechanical behavior in fatigue of composite materials by two non- destructive means: first, thanks to ultrasonic polar scans; the images resulting of these latter kinds of fingerprint of the elastic properties of the material, different for each orthotropic composite material.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for '(RE)Using Empty Buildings: Adaptive Architectural Types as an Instrument of Social Inclusion for Youth Homeless' in the context of a Horizon Europe call.

assistant: **Objectives**

In 2020, the OECD estimated that circa 38 million buildings in Europe were empty, exposing underlying governance weaknesses for adapting and reusing empty buildings. This needs to be put into perspective with circa 700,000 homeless youth living rough or in emergency lodging each night in Europe. An obvious societal paradox, therefore, exists between the high availability of empty buildings and youth homelessness, calling for a more inclusive and cohesive social dwelling model. These challenges are not new, and architecture has long attempted to solve them through, for example, segregated clustering of architectural types-buildings such as Montagu Burgoyne youth pastoral colony (1829, Potton, UK). My research project, however, aims to critically compare successful contemporary architectural types-buildings of So Stay Hotel (2016, Gdańsk, Poland), Intersectional City House (2016, Wien, Austria), Rukkila (2008, Helsinki, Finland) and Pieter de Raadtstraat 35 & 37 (2014, Rotterdam, Netherlands), their morphologies, programmes of activities, design processes, experiences, ownership structures, governances offering novel socially inclusive collective dwelling-work-trainings models for homeless youth through the use of empty buildings. Through a 2-year fellowship at Polimi - under the supervision of Prof Carolina Pacchi, a leading expert in European cities’ development, a 3-month secondment at TU Delft and a 4-month non-academic placement with ‘Avanzi’ - involving on-site archival research, post-occupancy, semi-structured qualitative interview and co-design methods, I intend to conceive a theoretical framework on ‘ReYouth Types’ and to implement ‘ReYouth Types toolkit’, a new set of design principles. Thus, I will provide European educators, urban and architectural designers,