RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Launching the First 360° Crowdsourced Live Video Platform.' under Horizon 2020.

assistant: **Concept**

Almost everyone is a camera[wo]man today and lots of people share content online. Just on YouTube: 60 hours of video every minute = one hour of video every second, over 4 billion videos are viewed daily, 3 billion hours/month, 70% of traffic comes from outside the US/ localized in 39 countries and across 54 languages  Several technological trends enable the ability to broadcast live video by almost anyone.Our Solution Watchity is a platform for crowdsourced live video content in which an organization can capture videos from a multitude of users recorded with any device. Watchity allows the organization to issue a comined live multicamera video that is able to display multiple views on one single event, event or place. The core of the platform is the patent-pending technology for the capturing, generating, distributing and reproducing of multicamera videos. We call those crowdsourced videos watchits.Our overall objective for the Phase II Project is create more sales for our company by scaling-up the current system with additional features that provide more benefits to users and/or that give us access to more target market segments including platform optimization (scalability, new components and optimize usability), platform debugging (overcoming detects and future technological challenges), adaptation to additional sectors (security, specific features). The goals for Phase I are a technological feasibility study and business plan.Our solution Watchity is completely European. Of course, we are a European company, but also our beta users are all based in Europe, our team consists of Europeans and our aim is to contribute to Europe catching up regarding online video production and consumption. Our revenues are likely to come from within Europe at first but we are eager to e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Highly efficient, High temperature, Hydrogen Production by Water Electrolysis' in the context of a Sixth Framework call.

assistant: **Objectives**

It is proposed to develop a high temperature water electrolyser with very high electrical efficiencies. The Hot Elly project has demonstrated that a breakthrough in water electrolysis efficiencies is possible by going to high temperatures (900-1000°C). The electrical efficiencies demonstrated in the Hot Elly electrolyser was close to 92% compared to 50-60% in traditional alkaline electrolysers. By making use of an external source of heat such as concentrated solar, it is possible to increase the electrical efficiency even further.The project aims to make use of the materials and technological developments that have been made in the last 10 years on planar SOFC technology and to apply to develop and evaluate a planar Solide Oxide Water Electrolyser (SOWE). Two different technologies will be developed using the SOFC cells as a starting point: anode supported cells and metal supported cells. The degradation of the SOWE will be analysed and the main mechanisms identified. Improved metal alloys and coatings as well as anode and cathode materials will be developed to limit any corrosion. The objective the project will be to demonstrate a degradation inferior to 1%/1000 hours on a short 5x5 cm2 stack for a period of 2000 hours.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Cross-platform Open Security Stack for Connected Devices' in the context of a Horizon Europe call.

assistant: **Objectives**

IoT developers face a very fragmented landscape made of very different devices, from bare metal devices with few KB of RAM and limited or no security protection to devices equipped with powerful support for AI and with built-in hardware (HW) to implement Root of Trust (RoT) and Trusted Execution Environments (TEE). Such different devices coexist, and it is an open challenge to guarantee an acceptable level of security across the whole system to avoid “easy” entry points for attackers. The complexity is further exacerbated by the existence of many HW platforms, general purpose but also domain specific, each implementing proprietary instances of RoT and TEE that prevent or make it very difficult for applications and security services to interoperate. CROSSCON aims at addressing all these issues by designing a new open, flexible, highly portable and vendor independent IoT security stack that can run across a variety of different edge devices and multiple HW platforms to offer a consistent security baseline across an entire IoT system. A high-level assurance is guaranteed by the formal verification of the stack specifications. CROSSCON stack offers a unified set of trusted APIs to the layers above. It is modular and among all the security features it offers is possible to configure only the ones needed depending on the underlined HW and firmware. It leverages the security features already implemented in the layers below. In case such security features are missing, like in bare metal devices, the stack offers an entire TEE implementation suitable for such devices. As devices are getting more powerful and use cases more complex, there is the need to add new trusted services as building blocks to implement security at the higher levels, such as protection of the models given i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Pushing the boundaries of general equilibrium theory with asymmetric Information' (PUBOUNGEASIN).

assistant: **Innovation**

In general equilibrium models with time and uncertainty, even if markets are complete the competitive allocation of resources will nonetheless be inefficient in the presence of asymmetric information, especially when some traders have private information concerning future assets payoffs.This inefficiency can in some cases be quite severe, leading even to the vanishing of some financial markets, limiting the scope of risk and uncertainty protection that the individuals in a given society can guarantee for themselves. If we could put aside the standard assumption in almost every general equilibrium model of price taking behaviour by all traders, it would be possible to introduce strategic behaviour, communication, and signalling in these models in such a way that at least part of the private information could be revealed, thus leading to an increase in overall economic efficiency.This is the main objective of this proposal, to develop new economic general equilibrium models that could enlighten us about these problems, and give us (and hopefully some decision makers) clues on how to contribute to improve financial markets efficiency, which is a matter of extreme importance. This type of problem has been the researcher PhD Dissertation fundamental goal, but he intends to pursue this same line of research even further, by visiting two highly rated European economic research departments as a postdoctoral fellow.The type of problems he tries to solve pose very difficult modeling mathematical problems, and for this reason it will be very beneficial the contact that he will have with innumerous mathematicians and mathematical economists that work or collaborate at CERMSEM, as well as the realization of joint research with Piero Gottardi (University of Venice), one of the world'
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Affordable DNA Mapping using Solidstate-Nanopores' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

DNA analysis will become an important clinical tool in identification the composition of microbial species living in the gut. The most dominant technique at the time is based on PCR amplification of the 16s rDNA gene and subsequent sequencing of the variable region in the gene. This method however is limited in the amount of detail it provides and is notoriously susceptible to primer bias. Furthermore, due to the requirement of a PCR machine and sequencer the technique is too expensive and time consuming for a clinical setting. Over the past few years nanopores have been heralded as a cheap alternative for biomolecular analysis. Specifically solid-state nanopores, which consist of a small pore in a solid membrane, have the potential for cost-effective mass-production in cleanroom facilities. Furthermore, since these pores can detect double stranded DNA they can easily be used for analysis of DNA maps.In this proposal I suggest to use DNA mapping with solid state nanopores. The basic idea is to sequence-specifically label DNA molecules using DNA Methyltransferases and synthetic analogues of the natural cofactor S-adenosyl-methionine. The pattern of labels attached to the DNA is unique for the underlying sequence.In my Ph.D. I used this method to transfer fluorescent dyes to the DNA and subsequently extracted the DNA map using super resolution fluorescence microscopy. In this case, the attached label will induce a current-drop when the DNA molecule translocates through the channel. The extracted current-trace will then be converted to a DNA map in basepairs and can be used to match to a real sequence. This proposed method can be used to identify genomic elements and eventually be used to recognize species, for a fraction of the cost of 16s rDNA sequencing.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'tPA-Nanoconstructs for Treating Acute Ischemic Stroke: a Technical and Commercial Analysis' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Acute ischemic strokes result from the occlusion of cerebral vessels by blood clots causing neurological complications, brain damage and death. Based on WHO reports, stroke affects 17M people per year worldwide, with 6M deaths and 5M survivors suffering long-lasting disabilities. Recent statistics estimate an EU direct healthcare cost for stroke of €20B and indirect costs, due to disabilities and lost productivity, of €25B. The two current treatments – thrombolysis and thrombectomy – come with limitations and considerable side effects. Thrombolysis can be safely administered only to a small cohort of patients (about 5%) whereas thrombectomy induces disabilities in 50% of the cases. Moved by the societal, economical, and emotional burden associated with stroke, this proposal aims at developing and validating more effective and less toxic therapies via the combination of the clinically approved molecule tPA and rationally-designed, discoidal polymeric nanoconstructs (DPNs). As compared to tPA, the proposed thrombolytic nano-agents (tPA-DPNs) are expected to provide faster blood clot dissolution; safer administration profile; longer blood circulation and stability. On the technical side, tPA-DPNs will be re-designed to improve their biodegradation and excretion profiles; validated in FDA-recognized stroke models for neurotoxicity and therapeutic efficacy. On the commercial side, a patent portfolio covering the fabrication and utilization of tPA-DPNs will be secured, together with thorough market and business analyses. This will facilitate the interaction with pharmaceutical companies that are investing in the fast growing markets of high-tech drug delivery systems and stroke diagnostics and therapies. tPA-DPNs are expected to alleviate the economic burden on healthcare sys
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Colour vision in the dark: ecological, physiological and structural basis of rod-rod colour opponency in the frog retina' in the context of a Horizon 2020 call.

assistant: **Objectives**

Most vertebrates, including humans, cannot ‘see colour in the dark’ because the retinal rod photoreceptors that mediate vision in dim light usually come in a single spectral flavour (“green”), precluding spectral comparisons. But frogs and some salamanders have an additional ”blue”-rod type, potentially allowing for purely rod-based colour discrimination. Using behaviour, I recently demonstrated that this is indeed the case: frogs do make spectral comparisons down to the absolute visual sensitivity threshold. However, the ecological relevance of nocturnal colour vision and the structure and function of the retinal circuitry underlying rod-rod spectral comparisons, and enabling the simultaneous preservation of sensitivity and spectral resolution, have not been explored.Thus, this proposal seeks to establish the purpose as well as the underlying retinal physiology and circuit implementation of frog colour discrimination near the visual threshold. For this, we will combine natural scene imaging, high-throughput multi-electrode array recordings from 1,000s of retinal ganglion cells and synaptic-resolution serial section electron microscopy of the blue-sensitive rod circuitry. This will enable unraveling which visual information is available to be used, and how it is processed, to reach the low-light limits of colour discrimination performance available to the vertebrate eye. Our research will also provide a link between the more intensely studied retinal circuits of fish and mammals, providing important insights about the evolution of vertebrate retinal networks’ architecture and computations. Finally, the topic of ‘colour vision in the dark’ is one that attracts considerable public interest, so this project will create valuable opportunities for public engagement with the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Zooplankton OPAL and Iron Study (ZOOPALIS) - Investigating the effect of grazing on Si and Fe recycling', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

In the world ocean, flux of biogenic carbon and biogeochemical cycles of carbon and essential elements for primary production (Si, Fe, N) are influenced by complex biological processes and food-web interactions. Determination of key processes and their mechanistic understanding is required for an adequate parameterisation of these interactions in regional and global models that aim at predicting the response of ecosystems and biogeochemical cycles to global change. International research programs like IMBER call for a scientific approach that combines biological and biogeochemical expertise to achieve this goal. Further need for investigation exists especially for food web mediated recycling of elements and whether it takes place at the surface, in the mesopelagic zone or at the sediment.The proposed study ZOOPALIS targets the effect of grazing on the dissolution of biogenic silica (BSi), Fe recycling and bioavailability, and decoupling of C, Fe, Si and N elemental cycles. Core to all experiments are diatom cultures, marked with multiple stable or radioactive isotopes. Special emphasis will be put on determining the speciation of recycled iron, in the light of Fe limitation of primary production in vast oceanic regions. Decoupling and recycling intensities will be assessed for key organisms (copepods, krill, appendicularians) and specialized feeding behaviour like benthic suspension feeding or coprophagic feeding of copepods.Recycling and preservation of BSi embedded in fecal pellets will be studied by means o f batch and flow-through reactor experiments. Results will be integrated in 1D/3D coupled physical-biological models developed within the framework of ongoing studies making the proposed project strongly interdisciplinary in nature by combining, in a concerted eff
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Optical Sequencing inside Live Cells with Biointegrated Nanolasers' (HYPERION) targeting Horizon Europe.

assistant: **Abstract**

Deciphering the code of life has sparked one of the biggest scientific endeavours in human history. Today, 18 years after the completion of the Human Genome Project, databases around the globe host over a million genomes. Surprisingly, one of the most important results that has emerged from this abundance of genetic information is how diverse and complex the processes are that control the constant regeneration, preservation, and adaptation of life. Understanding the relationships between cellular genotype and phenotype is therefore of fundamental importance in developmental biology as well as in the biomedical sciences. Many molecular mechanisms that shape our body during our life are still largely un-known due to the limitations of current sequencing technologies which can only glimpse a single moment in time. In stark contrast, biological cells constantly monitor their function and can, if needed, quickly adjust to changes in their environment by the transfer of information between the nucleus and the cellular protein machinery in form of RNA. Yet despite their essential function no technique can record these highly dynamic profiles of intracellular RNA. Gathering transcriptomic profiles from intact cells and within living organisms therefore represents a major challenge for any existing sequencing and sensing technology.Here, HYPERION introduces an entirely new concept of optical sequencing to detect transcriptomic information in real time and inside living biological cells. It is based on ultra-sensitive plasmonic nanolasers that combine recent advancements in extreme optics with a new concept to spatially confine RNA molecules. These lasers could be adapted to sense other biomolecules and mark the beginning of a new era in intracellular biosensing. Like the titan g
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Metabolic flexibility in drought: Leveraging Portulaca for defining design principles for a combined C4-CAM pathway' in the context of a Horizon Europe call.

assistant: **Objectives**

Rising heatwaves and drought are severely affecting the capacity of crops to retain water and capture CO2 during photosynthesis, resulting in global yield reductions. One of the most promising approaches to enhance crop production in stressful conditions is to synthetically modify the photosynthetic capacity of plants. In nature, some lineages have evolved mechanisms like C4 photosynthesis and the Crassulacean acid metabolism (CAM) to cope with some of these aspects; While C4 species are extremely efficient at CO2 fixation but vulnerable to severe drought, CAM plants are less productive but very capable of coping with significant drought periods. Engineering a joint C4-CAM system that uses CAM features to fight drought, while still relying on the power of C4 can be a game-changer to increase crop resilience. For decades, the coexistence of C4 and CAM was considered incompatible in nature. An exception to the rule is found in the genus Portulaca where C4 species can trigger CAM when droughted. Despite the huge bioengineering potential of Portulaca, the molecular enablers that allow for C4-CAM to exist in this clade remain elusive. Previous phylogenetic and morphological studies across Portulaca indicate the combined C4 (Kranz anatomy) and CAM (succulence) leaf anatomy might be the main facilitator of C4-CAM. By combining anatomical studies, cell specific metabolomics and genomics with synthetic biology, I aim to identify the basic molecular determinants of the C4-CAM switch in Portulaca, and to leverage this knowledge to transfer CAM anatomical features to C4 species outside Portulaca as a proof of principle. This will set the basis for new rounds of engineering to achieve a fully functional C4-CAM switch. METACAM will provide a quantum leap to our understanding on how i