RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Molecularly Imprinted Materials for Integrated Chemical Sensors'.

assistant: **Objectives**

Objectives and content Whilst there are a number of sensor technologies that are suitable for the detection of inorganic chemicals such as metal ions, anions and inorganic gases, there is a need for specific sensors capable of measuring the wide range of organic molecules and biomolecules that are important in industrial. environmental and health surveillance monitoring. Bio-sensing techniques, in particular those based on antibodies, have shown some promise, but in general suffer from poor stability and high production costs. In the bulk phase it has been shown that Molecularly Imprinted Materials (MIMs) recognize and bind their target molecule with high affinity and high specificity. They also show significantly higher chemical and thermal stability than comparable bio-sensing species. and can he prepared at low cost. In principle, therefore, they are well-suited for use in a sensor. The purpose of this proposal is thus to develop an innovative chemical sensor technology based on novel MIMs for the real-time measurement of specific target organic chemicals and biomolecules, such as drugs, toxins, pollutants and food constituents. To achieve this end, the proposed work will include: - the synthesis of MIMs for selected representative target molecules, - the development of methods for producing thin films of MIMs as sensor coatings, - the determination of the optimum transducer configuration(s) for the MIM-based sensors (acoustic, field effect and optical technologies will be assessed), - the design and development of the sensor electronics and software (using a 'smart sensor' approach), - the evaluation of the performance of the optimum MIM sensor design(s) in terms of sensitivity and selectivity. The main expected achievements are: - successful synthesis of thin films
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Polyelectrolyte nanocomplexes' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The major goal of the proposed project is to facilitate the applicant’s reintegration to his home institute after a successful Marie Curie training period at the Surface Chemistry, Dept. of Chemistry, KTH, Stockholm. To reach this goal the host (Eötvös Lorand University, Budapest) offers a permanent position for him and provides the infrastructure necessary to implement the proposed research project. The proposed research project consists of two independent work packages. The first work package aims at developing and applying a nanoprobe technique to determine the optimal structure of DNA-polyelectrolyte complexes, which is an important step required to increase the efficiency of current non-viral gene delivery systems. The second work package will map the effect of multivalent ions on the interaction of a flexible polyelectrolyte and an oppositely charged surfactant, which will provide information how the strong ion-ion correlations, introduced by the multivalent ions, affect surfactant/polyelectrolyte self-assembly. Finally, the reintegration grant will allow the researcher to transfer his new competences (related to modern surface characterization techniques, e.g. DPI, AFM, QCM-D, ellipsometry) to the host institution of the reintegration period and to the wider audience of its students.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Multi-instrumental research on waves in the polar atmosphere' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Atmospheric gravity waves have a clear impact on the dynamics of the mesosphere. In particular breaking gravity waves are always accompanied by a negative momentum flux divergence, which is essentially a momentum flux convergence. This leads to an accele ration of the background flow and consequently to an adiabatic cooling of the polar summer mesopause. In the MINERWA project for the first time coordinated momentum flux measurements will be carried out by the use of different lidar and radar instruments. Using the ALOMAR sodium lidar will provide us with wind and temperature profiles in the altitude range from 80 - 100 km. Together with the ALOMAR ozone lidar the temperature profile from 10 - 70 km can be determined by Rayleigh scattering in the cloud-fr ee part of the atmosphere. This data set will be extended by the use of the EISCAT VHF and UHF radars by the means of additional wind measurements in the mesopause region. This comprehensive data set will allow to calculate momentum flux in the mesospau se region and to determine the source altitude of the observed gravity waves. Measurement campaigns during summer as well as during winter will show the seasonal variability of atmospheric gravity wave activity and momentum flux. In this project I like t o work at the Norwegian host institute for two years in order to expand my scientific horizon, scientific experience, and network of scientists. This work will contribute to continued use and further development of an advanced U.S. lidar instrument at a N orth-European Research Observatory and thus strengthen the European scientific excellence. In addition to exchange of expertise with the host institute, collaboration with international research groups at ALOMAR and at EISCAT is possible and desired.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The compact LIBS module for advanced materials analysis' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Anteryon BV has a track record of more than 30 years in the R&D, manufacturing and marketing of refractive optical components and modules for a variety of niche market applications. Since 2010, Anteryon has been expanding in providing customized optical solutions for compact optical encoders and spectrometers. As a next step in this roadmap Anteryon envisages to accomplish a breakthrough in user access, size and cost reduction of a fast growing spectroscopic materials analysis technique, namely Laser-Induced Breakdown Spectroscopy (LIBS). The name Colibri stands for compact LIBS module for advanced materials. The novel Colibri module is carrier for a breakthrough in LIBS and will enable a more efficient, affordable, and more wide-spread use this spectroscopic technology for the analysis of materials. In this way, the increased use of LIBS will also contribute to the social themes and to the efficiency in executing European programs in the field of waste management, environmental protection, ecological footprint reduction, food safety control and health care. The Colibri module is a novel architecture and manufacturing platform that will be available as a standard plug-in module for compact, cost-effective, robust reconfigurable and user accessible spectrometers.The  proposed Colibri  module  satisfies spectrometer users  needs to measure in real-time and in-line without compromising the LIBS spectral accuracy and at affordable costs (at least 4 times lower than the state of the art).  The Colibri module allows reconfiguration of the spectrometer for different applications  by adapting software only. These features will boost the user accessibility and market  size  of affordable LIBS technology.  The feasibility assessment under Phase 1 will include a business plan incl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'The genetic basis of the convergent evolution of fungal multicellularity' (Multicellularity).

assistant: **Innovation**

The evolution of multicellularity (MC) has been one of the major transitions in the history of life. Despite immense interest in its evolutionary origins, the genomic changes leading to the emergence of MC, especially that of complex MC (differentiated 3-dimensional structures) are poorly known. Previous comparative genomics projects aiming to understand the genetic bases of MC in one way or another relied on gene content-based analyses. However, a pattern emerging from these studies is that gene content provides only an incomplete explanation for the evolution of MC even at ancient timescales. We hypothesize that besides gene duplications, changes to cis-regulatory elements and gene expression patterns (including protein isoforms) have significantly contributed to the evolution of MC. To test this hypothesis, we will deploy a combination of computational methods, phylogenomics, comparative transcriptomics and genome-wide assays of regulatory elements. Our research focuses on fungi as a model system, where complex MC evolved convergently and in subsequent two steps. Fungi are ideal models to tackle this question for several reasons: a) multicellularity in fungi evolved multiple times, b) there are rich genomic resources (>500 complete genomes), c) complex multicellular structures can be routinely grown in the lab and d) genetic manipulations are feasible for several cornerstone species. We set out to examine which genes participate in the building of simple and complex multicellular structures and whether the evolution of regulome complexity and gene expression patterns can explain the evolution of MC better than can traditionally assayed sources of genetic innovations (e.g. gene duplications). Ultimately, our goal is to reach a general synthesis on the genetic bases of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Insect-plant relationships: insights into biodiversity and new applications' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

FlyHigh studies underexplored phytophagous and saprophagous flies and geophyte plants aiming to obtaining ecological and evolutionary data that will be used to elucidate ecological features of fly species that could be exploited for artificial mass production of flies. Artificial mass rearing of flies produces beneficial end products, the flies themselves or their larval stages, that could be applied for different services in agriculture, ecological farming or as bio-agents for e.g. complementary pollination services in natural or greenhouse environments. The main aim is to facilitate cross-sectorial transfer of knowledge and training of researchers as well as technical staff in bridging the gap between scientific results and their application into novel business ideas.The excellence of the project lies in the synergy of basic and applied ecology for exploring and developing new protocols and end products. FlyHigh brings together experts with well documented scientific achievements of the focal organismal groups and on evolutionary analyses with early stage researchers with the same research focus, with experts on insect mass rearing techniques. The relevance of FlyHigh results from integration of project aims that may result in innovative results of broader impact that will benefit the ERA institutions as well as the TC partner. The results could be advantageous in developing new ideas for future use e.g. flies could complement or even replace the presently used managed pollinators in greenhouse productions of many greenhouse products.  The obtained data will also allow us to estimate the possible biogeographic events that can help explain the evolutionary history, current distributions and future biogeographic patterns of some bulb plant and fly groups  in South Afric
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Dynamic nuclear polarization - enhanced high resolution solid-state NMR spectroscopy for atomic 3D structure determination of functionalized nanotubes and other nano-sized objects' in the context of a Seventh Framework call.

assistant: **Objectives**

This project aims at developing the instrumentation and methodology required to perform solid-state sub-nanometer scale structural studies by Nuclear Magnetic Resonance (NMR). In the last decades NMR has proven to be a priceless tool to probe structure and dynamics of systems as diverse as glasses, metal surfaces, polymers and proteins, etc. However, the low sensitivity of the technique currently limits its outreach in material science, chemistry and biology. In order to overcome this limitation, we plan to use a technique called Dynamic Nuclear polarization (DNP) which is able to hyperpolarize nuclear spins. The DNP phenomenon, discovered at low magnetic fields (< 0.3 T), is far from being new but its usage at high magnetic fields (5 to 20 T and more) constitutes an exciting ongoing challenge. Compared to traditional NMR where the signal originates from thermal polarization, DNP enables us to enhance the NMR signal to noise by 1 to 4 orders of magnitude (depending on the nuclei) by transferring the magnetization of unpaired electron spins (polarizing agents) to the surrounding nuclear spins. Utilizing emerging high frequency microwave technologies, optimized polarizing agents together with state of the high resolution solid-state NMR instrumentation and methods, we plan to develop original magnetic resonance experiments at high magnetic fields. This technique should allow bringing down the NMR detection threshold to micro/nano-molar concentration, studying larger molecular systems and performing multidimensional experiments orders of magnitude faster. The project will lead to numerous interdisciplinary applications to illustrate the potential of DNP-enhanced NMR to characterize new materials for the nanotechnologies (functionalized nanotubes, molecular wires, etc.), ne
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Fully Networked, Digital Components for Photon-starved Biomedical Imaging Systems' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

SPADnet aims to develop a new generation of smart, CMOS-based large area networked image sensors for photon-starved biomedical applications, build ring-assembly modules for Positron Emission Tomography (PET) imaging, and carry out performance tests in a PET system evaluation testbed.<br/>While suited to applications offering repetitive measurement techniques, existing sensors are not well adapted to single-shot, rare events often occurring in diagnostic tools based on specific radiation detection, PET, SPECT, gamma cameras, and other minimally-invasive / point of care tools. In addition, the relatively small field-of-view of existing sensors is a limiting factor.<br/>SPADnet's prime objective is to develop a scalable photonic component for large format, rare-event imaging. The core of the component will be a SPAD array implemented in CMOS. Large formats will be achieved by tessellating several tens of dies in abutment style using innovative packaging techniques based on through silicon vias (TSVs).<br/>The ability to stamp the time and position of each photon impingement in a burst event offers a second key advance. The concept of spatial oversampling is introduced, where a single measurement is partitioned into a myriad of sub-measurements, occurring simultaneously. The difference is that in space oversampling many SPADs will detect the same event independently, thus reducing the dead time on average by the number of detectors involved.<br/>The decomposition of the large format imager to a network of independent arrays is key to managing massive data streams. In conventional PMTs or SiPMs, the sensitive device produces a stream of analog electrical pulses. The photonic component proposed in this project on the contrary generates streams of precomputed digital data.<br/
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Catalysis for Cancer Treatment.' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The increased incidence and mortality of tumors that do not respond to standard of care or other targeted therapies is a major challenge in clinical management of these cancer patients. In order to provide innovative therapeutic avenues for treatment refractory patients, it is urgent to develop novel mechanisms of anticancer drugs mode of action that will overcome the drawbacks of current therapies. In Cat4CanCenter, we will merge the research fields of metal-based catalysis for drug development and innovative delivery routes with cancer biology and immunology, applied to one of the deadliest cancers, glioblastoma (GBM), a fatal primary brain tumor for which no curing therapy exists, due to its location within the brain parenchyma and complex tumor microenvironment. Many potential drugs failed in the clinic due to their inherent toxicity and off-target side-effects, which add up to the challenges in reaching the protected brain site. Recently, innovative catalyst design enabled synthetic transformations in the presence of biological molecules. In Cat4CanCenter we will develop four innovative approaches to treat GBM. This new methodology requires the design of cage protected catalysts that will be delivered to targeted cell types using advanced lipid nanoparticle technology. Next, the catalysts will convert nontoxic prodrugs into active drugs within the GBM bulk. Our groundbreaking strategy aims for successful therapies to treat glioblastoma, by developing complementary approaches to therapeutically tackle the complexity of this disease. The new strategies, catalysts and prodrIn this project we explore a new avenue to treat glioblastoma, which is the most difficult cancer to target. In a collaborative program we develop biomimetic transition metal catalysts (key expertis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Full scale innovative composite windows frames for Regional Aircraft fuselage barrel on-ground demonstrators' (2014-2020) under Horizon 2020.

assistant: **Objectives**

Validation at full size level of CFRP windows frame manufacturing process (Thermoplastic) and fabrication of 2 shipsets for Regional Aircraft Fuselage barrel on-ground demonstrators. Moreover, an industrial and cost evaluation based on a pre-defined production business case is requested including hypotheses of high volume automated solutions
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Bright High Spin Molecular Semiconductors' (BRIGHTS).

assistant: **Concept**

BRIGHTS builds on the proposer’s discovery of high photoluminescence quantum efficiency, PLQE, from high spin states excitons (S = 1, 3/2, 2) in molecular semiconductors. This is underpinned by their recent development of spin doublet molecular semiconductors where bright spin doublet excitons support efficient OLED operation, particularly for red and near-IR.  High spin molecular systems have previously been developed for their quantum properties but have been non-luminescent, preventing optical readout.  The luminescent systems developed in BRIGHTS open up new spin-exciton science and new opportunities for optical writing, manipulation and reading of spin states.  The core of the project is the development of new materials systems with high spin excitons that have high PLQE. These materials developments include: (a) high PLQE in spin doublet systems, with electron acceptor substitutions and designs for near-IR emitters, used to construct: (b) systems where photogeneration evolves from spin doublet to quartet, with optimisation of intersystem and reverse intersystem crossing via engineering of charge transfer states, and new designs using TADF emitters; (c) conjugatively coupled di- and poly-radicals.  For diradicals this will focus on exploring the inter-radical coupling to engineer PL in both triplet and singlet manifolds.  This builds on the proposer’s discovery of red-shifted singlet exciton PL from zwitteronic charge-transfer character singlet excitons.These materials systems will be explored for applications in:  (d) spin-optical applications for sensing.  Optical spin pumping and optically-detected magnetic resonance, ODMR, will be explored and developed for sensing, at high and low B fields, and for possible biomedical sensing;  (e) spin-controlled charge trans