RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Collective Adaptive Systems Enabler Kit'.

assistant: **Concept**

In 2008 Apple introduced the App Store. It was a watershed moment in the history of digitalization and it made a huge impact on human society. With the App Store, Apple created a sustainable model to leverage the potential of mobile computing by tapping into the creativity of developers at large.  We're currently on the cusp of a new chapter in the history of digitalization: the Internet of Things (IoT). The Internet of Things has been heralded as the Fourth Industrial Revolution and promises creative solutions to pressing business and societal problems. The Cassting project, from which CASEK arises, made important theoretical and methodological contributions to the Internet of Things.  But developments in the IoT have fallen short of expectations, and due to the complicated and fragmented context of the IoT, nobody has been able to do the same for the IoT that the App Store did for mobile computing – until now. The CASEK project sets the stage to dramatically accelerate developments in IoT through its sustainable marketplace model. CASEK will leverage the potential of the Internet of Things by tapping into the creativity of developers at large, powered by the Cassting framework.   During the CASEK project, we will focus on two aspects to support our ambition: business and technology. The business focus has as its objective to solidify a business and marketing plan. The technology focus has as its objective to develop a viable product offering.To best reach these objectives, the CASEK project seeks to galvanize and learn from a community consisting of researchers on the one hand and emerging entrepreneurs on the other, as we see these groups as the vanguard to mainstream commercial adoption, which is our ultimate goal. Both the business and technical focus will be execu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'MultimEDia transport for mobIlE Video AppLications' (MEDIEVAL) under Seventh Framework.

assistant: **Objectives**

Video is a major challenge for the future Internet. This traffic type is foreseen to account for close to 90 percent of consumer traffic already by 2012. However, the current Internet, and in particular the mobile Internet, was not designed with video requirements in mind and, as a consequence, its architecture is very inefficient when handling video traffic. It is the vision of this consortium that, as video is going to represent the majority of the traffic, the future Internet architecture should be tailored to efficiently support the requirements of this traffic type. Specific enhancements for video should be introduced at all layers of the protocol stack where needed, ideally supporting an incremental deployment.Following the above vision, the main goal of the current proposal is to evolve the Internet architecture for efficient video traffic support. The proposed architecture will follow a cross-layer design that, by exploiting the interaction between layers, can raise performance to values unattainable with individual developments. The following key issues will be addressed by the architecture: i) enhanced wireless access support to optimise video performance, ii) novel IP mobility architecture adapted to the requirements of video traffic, iii) transport optimisations for video distribution and iv) network-aware video services that interact with the underlying layers. The technology developed by the project will be designed taking into account the requirements of network operators for commercial deployment, and will aim at improving the Quality of Experience by users as well as reducing the associated costs for operators. Standardization and early incremental testing are considered key success factors for MEDIEVAL.The consortium is well balanced and combines the i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Friendly gamification business model based on intelligent data analysis to enrich consumers personalized e-commerce experiences', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Business Opportunity: within the e-commerce market - specially for SMEs, do not have the knowledge or the resources to use and/or accesses consumers’ data properly due the high investment they need in terms of costly tools & human resources. The best information that the ecommerce can gather comes directly from the consumers, which implies surveying them, which requires a big effort from the participants (to fill) and from the brands (requiring validation and analysis).Friendkhana added value: provides an innovative SaaS solution to make short, intuitive quizzes that can be integrated with a single line of code in our client´s on line stores.  It generates real-time information about the users, - enhanced seamless with their social network data - to enrich user profiles to cluster a new data base, while they are having a more personalized experience. Friendkhana offers a SMEs e-commerce with a competitive customizable solution that provides a richer database of their users to make better ROI-directed marketing campaigns while they benefit for better recommendations and a better customer experience.Phase 1 objectives is to accelerate the market adoption and international penetration of Friendkhana focus on preparing ourselves for the commercialization of at the international level (including route-to-market, marketing strategy, growth strategy, etc.) by evolving the product from TRL6 to TRL9 stageImpact: As a result of this project, Friendkhana will grow considerably, generating 55 new qualified jobs by five years after the project ending and generating a cumulative EBITDA of 58,9 M€
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Targeting RANK receptor as a novel therapeutic strategy in triple negative breast cancer'.

assistant: **Innovation**

Breast cancer is the most common malignancy among females in the western world, resulting in nearly half a million deaths annually, mainly due to metastatic disease. Triple negative breast cancer (TNBC) accounts for almost 15–20% of all breast cancers (300.000 women diagnosed worldwide per year) and is commonly diagnosed in women younger than age 40. TNBC remains a clinical challenge due to high rate of relapse, a propensity to form visceral metastasis and limited targeted therapies. Thus, there is an urgent need to identify novel targeted therapies for the treatment of the TNBC. TargetRANK is based on the innovative idea of generating novel drugs targeting RANK receptor – instead of its ligand RANKL – for the treatment of TNBC, as well as a new panel of anti-RANK human antibodies – for research and diagnostic purposes. Small molecule inhibitors generated during the project could plausibly be positioned as a novel targeted therapy for TNBC and anti-RANK antibodies commercialized for research applications due to the lack of specific antibodies on the market. The most important benefits of TargetRANK are based on the unmet need to improve the treatment of TNBC patients, and the economic burden for public health systems generated by standard non-selected and ineffective cancer treatments. In addition, if drugs against RANK prove to be efficient, TargetRANK derived assets could also clinically benefit most of the patients suffering bone metastasis that are currently treated with bone resorption drugs, denosumab and bisphosphonates. Although our products are aimed for breast cancer, they may be therapeutically relevant for other tumors expressing RANK as non-small cell lung cancer. RANK antibodies will allow to stratify patients that might benefit from RANK blocking molecule
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Multi-agent control: probabilistic reasoning, optimal coordination, stability analysis and controller design for intelligent hybrid systems' (1998-2002).

assistant: **Innovation**

The training objective of the network is to provide a core of European scientists with necessary multi-disciplinary skills for designing multi-agent control system. The primary measure will be the provision of 224 months of research training to four PhD students, and two post-doctoral researchers. The research training will take the form of taught modules, academic research, teaching secondments, and will be supported by the provision of summer schools (with invited external experts), academic staff exchange, and secondment to an industrial mode in the network. Secondary measures provided by the network involve dissemination of results and methods to the wider community. These measures will include publication of research results using open media (internet), incorporation of results into undergraduate programmes, and where appropriate, provision of formal courses to industry. As part of these secondary measures, external participation in the summer schools will be encouraged.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Fundamentals of Combustion Safety Scenarios for Hydrogen' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Hydrogen is a powerful energy vector but its deployment at the scale considered today by governments and companies cannot be achieved if safety associated to combustion hazards is not mastered and regulated. Hydrogen leaks occur and lead to fires and explosions which must be prevented. To do this, regulations are needed but these regulations are based today on an incomplete understanding of the fundamental mechanisms controlling the combustion of hydrogen in air or have to consider new usages of hydrogen such as transportation (aircraft, trains, cars). SAFE-H2 combines theory, high-precision experiments and simulations to provide reliable knowledge on the ignition, propagation, acceleration, mitigation of hydrogen-air flames in three canonical cases: flames stabilized on a hole, flames interacting with a wall, explosions in closed vessels. The proposal gathers (1) IMFT where two experimental sites, dedicated to hydrogen, will be used for low (<40 kW) and high power (300 kW) experiments and (2) CERFACS which provides the High-Performance 3D simulation tools used to compute all IMFT experiments. Experimental diagnostics coming from the aerospace field will be applied to safety scenarios at IMFT to validate simulation tools. SAFE-H2 will focus on generic, simple cases to tackle the fundamentals of hydrogen-air flames so that simulation tools incorporate correct, validated physical models and can replace costly and dangerous experimental tests. All SAFE-H2 experiments will be designed to be used for simulation validations. These detailed comparisons  between simulation - experiment will be used to test models for 1) hydrogen-air chemistry in the gas phase and near walls, 2) autoignition and plate ignition, 3) flame-turbulence and flame-wall interaction, and 4) transition to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Regulation of pneumolysin in the human pathogen Streptococcus pneumoniae: A single cell approach', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Streptococcus pneumoniae is a major pathogen causing invasive (pneumonia, meningitis, bacteraemia) and non-invasive (acute otitis media, sinusitis) disease in young children and in elderly and/or immuno-compromised adults. The molecular mechanisms underlying S. pneumoniae virulence are not fully understood. Single-cell methodologies, including the sub-cellular localization of proteins by fluorescence microscopy, have been instrumental in studying fundamental processes in bacteria and these methodologies are potentially of great use to investigate S. pneumoniae virulence. Recently, we have developed a cell biology toolkit for S. pneumoniae, allowing us to perform gene expression and protein localization studies at the single cell level in live cells. A major S. pneumoniae virulence factor is pneumolysin which is encoded by the ply gene. Pneumolysin is highly immunogenic and binds to cholesterol in the membrane of host cells and its haemolytic activity induces cell lysis. Pneumolysin is one of the best characterized virulence factors of S. pneumoniae, but surprisingly little is known about its transcriptional regulation. Interestingly, pneumolysin is produced in the cytoplasm of S. pneumoniae and can only be released by lysis of the producer. This represents a fascinating paradox: if all cells lyse at the same time, the clonal lineage becomes extinct. Thus, mechanisms must exist to ensure that not all cells release or produce pneumolysin at the same time. This proposal is aimed at unraveling the molecular mechanisms underlying heterogeneous pneumolysin gene regulation and release using single cell analytical techniques. The host institute has excellent knowledge and facilities to perform S. pneumococcus molecular genetics and cell biology, and together with the single cel
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Deep-sea Sponge Grounds Ecosystems of the North Atlantic: an integrated approach towards their preservation and sustainable exploitation', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The objective of SponGES is to develop an integrated ecosystem-based approach to preserve and sustainably use vulnerable sponge ecosystems of the North Atlantic. The SponGES consortium, an international and interdisciplinary collaboration of research institutions, environmental non-governmental and intergovernmental organizations, will focus on one of the most diverse, ecologically and biologically important and vulnerable marine ecosystems of the deep-sea - sponge grounds – that to date have received very little research and conservation attention. Our approach will address the scope and challenges of EC’s Blue Growth Call by strengthening the knowledge base, improving innovation, predicting changes, and providing decision support tools for management and sustainable use of marine resources. SponGES will fill knowledge gaps on vulnerable sponge ecosystems and provide guidelines for their preservation and sustainable exploitation. North Atlantic deep-sea sponge grounds will be mapped and characterized, and a geographical information system on sponge grounds will be developed to determine drivers of past and present distribution. Diversity, biogeographic and connectivity patterns will be investigated through a genomic approach. Function of sponge ecosystems and the goods and services they provide, e.g. in habitat provision, bentho-pelagic coupling and biogeochemical cycling will be identified and quantified. This project will further unlock the potential of sponge grounds for innovative blue biotechnology namely towards drug discovery and tissue engineering. It will improve predictive capacities by quantifying threats related to fishing, climate change, and local disturbances. SponGES outputs will form the basis for modeling and predicting future ecosystem dynamics under
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Burning Behaviour of Curtains and Drapes : Flame Spread Measurement Using a Large Ignition Source' (1994-1998) under Fourth Framework.

assistant: **Objectives**

Curtains and drapes are not always regarded as building materials and are not included in the European standardisation that is going on in the field of reaction to fire of floors, walls, ceilings, etc. in relation to the Construction Products Directive. Nevertheless, they can also play an important role in the spread of fire through buildings and they need to fulfil minimum requirements for fire safety in each European country. Consequently, the harmonisation of testing methods for the burning behaviour of curtains and drapes is necessary on a European level. As far as low risk areas are concerned, two methods for measuring ignitability and flame spread of curtains have already been published, both using a small flame as an ignition source. For high risk areas, however, ignition by means of larger ignition sources may occur. Unfortunately, no test method is actually available.The first aim of the project is to establish a test method for assessing the burning behaviour of curtains and drapes using a large ignition source simulating a waste paper basket. In order to simulate a burning waste paper basket, the ignition source needs to be a combination of radiant heat and flames. One main restriction of the test method is that it needs to be a small scale test method measuring only ignitability and flame spread parameters. Reaction to fire parameters like smoke development, heat release and toxic components are not taken into account.The second aim of the project is to try to provide a harmonised European system that could be used to replace all the different existing national systems, especially those for the contract or public area. To try to reach this objective, the new method developed in this project will be used in combination with the two above mentioned methods tha
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Epidemiology and pathogenesis of porcine post-weaning multisystemic wasting syndrome' (PMWS) under Fourth Framework.

assistant: **Objectives**

Research objectives and content The main objective is to investigate the pathogenesis and epidemiology of PMWS, and to determine the causal link of porcine circovirus (PCV) with this new syndrome. It includes clinicopathological study of natural cases and experimental reproduction of PMWS by inoculation of PCV, the development of techniques for detection of PCV, and collection of epidemiological information in PMWS-affected farms.Technical milestones are standardisation of an immunocytochemical technique for detection of PCV-antigen, and development of a PCR technique for detection of PCV genome. Sequencing of PMWS-related PCV will allow design ofspecific DNA probes to differentiate PCV derived from PK-15 cells and from PMWS cases. A ELISA technique for PCV antibodies will be standardised, and well as immunocytochemical techniques for porcine monocyte-macrophage markers for its use in formalin-fixed, paraffin-embedded tissues. Training content (objective, benefit and expected impact) The candidate will be Doctorate, and could present at the exam for Diplomat of the ECVP. Trained candidate will be able to work as a pathologist, and to conduct research on animal infectious diseases. Links with industry / industrial relevance (22) The design of vaccines to prevent PCV-infection may be of interest for the vaccine-industry. Fort Dodge Veterinaria traces the host institution for collaborative research on this disease.