RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Heat and mass transfer in micro-channels' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

For the instruction of young researchers from various European countries the most advanced experimental and numerical methods and procedures will be used. The appropriate means are available at the universities and research institutes of the project partners. The experimental and numerical work will cover various topics, e.g. single-phase flow, flow boiling, convective condensation, two-phase flow patterns with transitions, void fractions, onset of nuclear boiling in laminar flow, two-phase flow structures and numerical work on modeling the two-phase flow phenomena. Different parameters will be varied during the experiments, e.g. fluids, channel geometries and sizes, surface roughness, etc. to obtain information about basic phenomena of heat transfer in narrow spaces. Workshops, seminars and at the end of the project an international seminar will be hold to exchange and publish the obtained results.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Role of Retinoic Acid signaling in cDC1 and cDC2 on intestinal immune homeostasis and disease'.

assistant: **Innovation**

For the past years, it has become undeniable that environmental signals have a great impact on the intestinal immune system. Among them, the Vitamin A (Vit A) has a central role in intestinal immunity. Consequently, the Vit A deficiency (VAD) is associated with an increase of infectious diseases and the supplementation of Vit A to pregnant mothers and children is a protocol defined by the World Health Organization. The vit A is mostly absorbed in the small intestine and derived into Retinoic Acid (RA), especially by conventional dendritic cells (cDC). Studies on the impact of RA on intestinal immunity, including in the host laboratory, have highlighted a major impact of RA produced by cDC on the homing and the polarization of effectors cells, although the effect of the RA on specific cDC subsets remains unknown. The understanding of this effect is an essential step for manipulating the system while avoiding secondary effects, usually triggered by impacting such central metabolites as RA. We propose to define this specific action of the RA on cDC using cutting edge technologies and state of art techniques both developed in the laboratory and brought by the candidate. These techniques will allow the investigation of the RA effect on specific intestinal cDC subsets at transcriptomic and phenotypic levels under homeostatic and pathologic states. The host laboratory will develop the professional skills of the candidate by reinforcing his individual competences, including laboratory techniques, writing, critical and innovative thinking, and communication abilities. Those will be further enhanced by the participation to many national and international collaborations enabled by Dr. Agace’s strong network. The high-quality infrastructure provided to the candidate and his complem
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'k-NOW-casting'.

assistant: **Innovation**

Environmental monitoring is a key element of the EU agenda and its market is estimated to grow at a CAGR of 5.4% by 2018. Artys offers a disruptive Decision Support Service - DSS, to manage emergencies caused by extreme weather events, based on the analysis of Smart Rainfall System – SRS’ measurements. SRS is the only nowcasting system (IT patented, EU pending; Artys uniquely owes its rights) providing real-time spatial rainfall maps on a detailed scale, by means of the analysis of satellite television’s signals, received by commercial parabolic antennas.Artys provides real-time evidences on hydrological risks related to intense rainfall, integrating SRS with other real-time sensor networks (monitoring e.g. rivers’ level and landslides), allowing timely alert validations and communications to citizens.Artys’ services are a new dynamic risk evaluation tool for public and private entities; our business model is focused on value added services (loan for use for the HW and multiannual subscription for services). That’s a disruptive market approach, because we make customers spread their investments, breaking market barriers.Artys has the ambition to become a reference EU service centre for nowcasting & alert validation. The feasibility study will analyse public (e.g. Civil Protection and Municipalities) and private (e.g. agriculture, industry, transports, aqueducts and waterways, mines and dumps, insurances) sectors, identify different classes of target customers, define marketing & communication strategy and market potentials.The good business models to face all the identified market segments will be identified, as well as a long-term strategy, insisting on the following issues: commercial plan, IPR, strategic partnerships, distribution channels, hiring policies.An operati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Development and demonstration of new systems for gas distribution inside the buildings'.

assistant: **Objectives**

At present, throughout the world, interior gas pipework is practically always made of metal. These materials cause no specific technical problems. However, their purchase and installation costs (fitting and assembly) are high and technologies used are not modern. On the other hand for other application (water, industrial gas) innovative systems, including new material for pipes and their associated assembly techniques, are available on the market. For domestic gas distribution several technical research were already engaged. These new techniques could reduce global cost of the installation, achieve a high level of safety, (at least comparable to conventional pipes) and allow the development of new user friendly applications. Then, the objective is to demonstrate that these innovative, techniques could be used and allowed by legislation (it is not this case today) for domestic gas distribution inside the building.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Within and across countries heterogeneity in international finance' to be submitted under Seventh Framework.

assistant: **Abstract**

Financial globalization has led to a large increase in capital flows together with increasing global imbalances. Understanding how investors structure their international portfolios and how such decisions interact with the real side of the economy has become a critical macro issue. Recently, policy makers have been advocating the understanding of capital flows and global imbalances as a necessary step to analyze the roots of the last financial crisis and its international transmission. Another important evolution is the larger role played by fast growing emerging markets. The world is getting more asymmetric as they feature very different characteristics compared to developed countries.INFINHET aims at developing new dynamic multi-country macro-models to better account for the heterogeneity across agents and across countries in order to answer age-old questions in international macro such as the benefits from financial integration, the adjustment of global imbalances, the dynamics of exchange rates and asset prices, international financial contagion, the international dimension of tax policies.The first part of INFINHET deals with new methods for dynamic stochastic models with heterogeneous agents/countries. Applications include normative questions regarding the welfare impact of policies in open economies and positive questions regarding the dynamics of asset prices and capital flows. The second part focuses on long-term issues in multi-country overlapping generations models. It analyzes the importance of asymmetries between countries on macroeconomic outcomes in a globalized world. Besides differences in growth and demographics, asymmetries in financial institutions, insurance mechanisms and welfare states are emphasized, with a particular focus on the specificities o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'European Laser Research Infrastructures serving Science and Industry' (Lasers4EU).

assistant: **Concept**

Lasers4EU is incorporating the major laser research infrastructures, in a large number of European member states, into a comprehensive virtual distributed laser research infrastructure that is offering to a broad user community, from academia and industry, access to an exceptional portfolio of technical and scientific capabilities.This unique set of instruments together with the specific scientific expertise at the host facilities allows Lasers4EU users to carry out high-level research in an extremely wide range of high-impact topics in life sciences, materials nano-processing, etc. Laser technology has experienced remarkable advances and breakthroughs and is now a key innovation driver for highly diversified societal applications and products, thereby substantially contributing to economic growth and to solving challenges in the areas of health, environment and energy. Through its strategic approach, Lasers4EU aims to strengthen Europe’s leading position and competitiveness. It facilitates long-term coordination of the laser research activities within the European Research Area and provides concerted and efficient services to scientific, industrial and medical researchers.The main objectives of Lasers4EU are to:•provide coordinated access to high-quality services based on a coherent and comprehensive consortium of 27 leading European laser installations offering to users from academia as well as from industry cutting-edge performances at the forefront of the laser technologies,•structure the European landscape of laser Research Infrastructure through enhanced access, extended geographical coverage, novel science diplomacy activities, improved synergies with other European networks and projects,•increase European human resources in the field of laser science by implemen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Support to the Chair and Vice-Chairs of the ERC Scientific Council 2011'.

assistant: **Concept**

The proposed Action will provide the necessary support to the Chair and Vice-Chairs of the European Research Council Scientific Council (ERC ScC) to achieve key milestones and deliverables of the ScC, which are required in the fifth year of implementation of the Ideas specific programme.Under the Seventh Research Framework Programme (FP7) and the Ideas specific programme, the Commission has established the European Research Council providing a competitive funding mechanism for investigator-driven frontier research on European level. One of the key structural components of the ERC is the Scientific Council consisting of 22 researchers at the highest level, representative of a large range of disciplines and institutional backgrounds and acting independently. The ERC ScC establishes and oversees the ERC's scientific management and the implementation of the Work Programme, including the peer review and the selection of peer reviewers.The potential impact of the project will be to ensure an efficient and well-managed operation of the ERC ScC. By providing high-level local support for the EcC Chair and Vice-Chairs who are based at their respective host institutions, the project will complement the activities of and allow efficient interfacing with the ERCEA. The proposed support is required as the ScC Chair’s duties amount to a full-time commitment and the corresponding duties of the Vice-Chairs demand a considerable part of their time. Their activities are diverse and intensive, ranging from preparing chairing, and following-up on the ScC and Board meetings, interfacing between the ScC and the ERCEA, liaising with the European institutions, and representing ERC in the media and at national, European and international meetings. Overall, the project is expected to contribute s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Forschung begreifen (Understanding Science and Research)' to be submitted under Horizon 2020.

assistant: **Abstract**

As the world is confronted with climate change it is of vital importance to show the impact of global warming and to promote sustainability. Due to this reason, one of three key focuses of the European Researchers’ Night in Austria will be to enhance the understanding and promote current research in the fields of climate and sustainability. The second key focus is citizen science, which is an efficient way to democratise science and to bring the public and science closer together for enhancing both public knowledge as well as understanding of science. Moreover, in order to open up new perspectives of seeing the world, it is more than necessary to understand arts and show the diversity of research in this area. In this context, the third focus of the European Researchers’ Night event “Forschung begreifen” (Understanding Science & Research) in Vienna will be Arts & Research. All three key focuses will be promoted in several pre-event activities such as trainings, workshops, challenges and conferences as well as in a broad spectrum of innovative activities at the actual European Researchers’ Night. This event will incorporate formats such as Science Slams and Science Cafes, more than 60 scientific booths and 16 workshops, as well as social activities to bring public and science closer together, but also to encourage young people to pursue a career in the STEM domains. Researchers from more than 25 domains and almost all significant research institutions in Austria committed to be part of the European Researchers’ Night activities. Moreover, support for the event and its promotion was stated by Austrian ministries (including also financial support), other public stakeholders, funding agencies and initiatives. The project “Forschung begreifen” integrates 5 partners with diff
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The ARM-B skin-allergy diagnostics patch is a compact, easy to apply, low-cost allergy testing product.' (ARM-B), addressing dissemination and exploitation.

assistant: **Impact**

Allogen Biotech is innovating the ARM-B allergy diagnostics patch technology for use in the healthcare sector and home-test markets. The company’s advanced biosensor concept draws on the simplicity and reliability of traditional skin-prick procedures, yet provides improved clinical outcomes and patient experience. The Allogen innovation is engineered as 50 mm stick-on disc-shaped patch, composed of a microarray device, which identify panels of allergic reactions. Each type of allergic response is interpreted as electrical impedance changes at individual biosensors. The allergy specialist acquires the test results in 5 minutes on a wide panel of common or specific allergens. The sensors register the degree of severity of an allergic reaction and may provide further information on specific testing. The ARM-B system offers unique advantages for the allergy therapist and patients alike. The patch device is non-intrusive – no need to pen-mark or prick large areas of skin: ARM-B microarray extends only 30 mm. The tine-microelectrode structure of the biosensor component ensures ultra-low invasiveness, penetrating only a few hundred microns of epidermis, not millimetre skin-prick depths. Therefore the ARM-B test offers a pain free consultation. The in vivo patch uses only picomole/nL, of a purified allergen microgel, minimising the risk of adverse side effects prevalent with skin-pricks – viz. nausea, raining, malaise. The device offers a large allergy dataset, a consequence of the microarray concept. The sensors are quantitative, so data on degree of allergic response or severity is collated. The solution to skin-oriented allergy diagnostics is applicable to several alternative market segments, not only accredited clinics and general practice with specialist allergy practition
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Cell-permeable peptides: physiological significance and biotechnological applications'.

assistant: **Concept**

At present, most bioactive drugs internalized by live cells are hydrophobic organic molecules that successfully cross lipid barriers but often lack the fine specificity that could be obtained from polypeptides or oligonucleotides. A first goal of this application is therefore to understand the mechanism of internalization of recently discovered cell-permeable peptides and to improve their efficacy. A second goal is to modify the latter peptides in such a way that their internalization by the cells will be followed by their entry into a secretion pathway with the objective to develop compounds that might translocate across the blood brain barrier. The proposal is primarily focused on two families of peptides that have been shown to translocate across the cell membrane. The Penetratin family is derived from the third helix of the DNA-binding domain of homeoprotein transcription factors and the Transportan family is derived from the fusion of galanin and mastoparan, two peptides involved in cell signalling. Penetratins and Transportans are internalized through a mechanism that differs from classical endocytosis and have been used by several groups to address biologically active hydrophilic cargoes into the cytoplasm and nucleus of live cells. We now want to better understand the mechanism of internalization of these peptides, to develop new vectors and to analyse the structural (size and structure) and biological (secondary effects) limitations of the cargoes that can be internalized. Starting from established peptidic sequences we shall use a combination of theoretical (molecular modelization) and experimental approaches to analyse how discrete modifications in peptide structure and lipid composition might affect lipid/peptide interactions and modify the internalization a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Heterologous expression of wood-rotting and litter-decomposing fungal genes involved in lignin degradation' under Seventh Framework.

assistant: **Concept**

Lignin is a highly recalcitrant integral polymer in higher plants and the second most abundant organic polymer in nature. Lignin degradation by white-rot fungi has been studied intensively in relation to highly important biotechnological applications such as biopulping, biobleaching and treating of pulp mill effluents. Indeed, lignin-selective fungi that degrade lignin in preference to cellulose are considered the most promising fungi for alternative energy saving applications in pulp and paper industry. Other important biotechnological applications of these fungi or their selected enzymes include biofuel generation and bioremediation, i.e. removal of toxic pollutants from soil and effluents. To make industrial applications feasible, an efficient production system for these enzymes would be needed Litter-decomposing fungi possess a similar lignin modifying enzyme system as wood-decaying white-rot fungi but relatively little is known about their potential and significance in the degradation of lignin, humus and organopollutants in soil. In this project ligninolytic enzymes of the litter-decomposing fungi and fungal oxalate decarboxylase, an essential part of effective lignin degradation, will be heterologously produced and characterised. The production of heterologously produced proteins will be scaled up to reach high levels of recombinant enzymes that will improve the utilization of these fungi in commercial biotechnological applications. The structural and functional properties of recombinant enzymes will be characterized at the University of Nottingham as well as within joint projects in EU and Europe. Importantly, to significantly strengthen her career the applicant will learn several novel and valuable techniques including gene array methodology, associated bioinfo