RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Benefiting from an improved agricultural portfolio in Asia' to be submitted under Sixth Framework.

assistant: **Abstract**

Neglected and Under-utilized Crop Species (NUS) are those grown primarily in their centres of origin or centres of diversity by traditional farmers, where they are still important for the subsistence of local communities, or were once more widely grown but are today falling into disuse for a variety of agronomic, genetic, economic and cultural factors. Some species may be globally distributed, but tend to occupy special niches in the local ecology and in production and consumption systems. While these crops continue to be maintained by socio-cultural preferences and use practices, they remain inadequately characterized and neglected by research and conservation.The aim of the project is to maintain agricultural diversity and to improve the agricultural portfolio, by supporting the use of NUS in Asian countries. Thus the project contributes to agricultural diversification, income generation and food security on a regional and international level. The proposed project will be based on cooperation between researchers working on genetic resources and NUS.The project links European researchers and expertise to their Asian colleagues to investigate the potential sustainable use of NUS, and to explore new opportunities for niche products, both for local and international markets. These goals are reflected in the make up of the project team, coming from European Union member states, Thailand, Cambodia, Vietnam, and P.R. China.The main objective of this project is to elaborate a list of recommendations and strategies for the sustainable use of priority NUS based on a multi-criteria assessment of Asian NUS. By providing an exchange platform for European and Asian experts and other stakeholder - jointly elaborating a list of recommendations for researchers and policy makers - the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Do Synechococcus regulatory networks underpin marine ecological distinctness?', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Cyanobacteria of the genus Synechococcus have a ubiquitous distribution in oceanic waters and are responsible for around a quarter of the primary production. The genus is genetically diverse, with at least ten phylogenetically distinct lineages or clades. The in situ community structure of these organisms is complex, with the specific lineages occupying different niches to populate the world’s oceans. Whilst such molecular ecological studies are effectively mapping the spatial distributions of specific genotypes, but the factors that dictate this global community structure, and the relationship between niche and genetic potential, are still poorly defined. This is important because changes in dominant picocyanobacterial lineages indicate major domain shifts in planktonic ecosystems, allowing us to assess changes in the rates of biogeochemical cycles. We propose here to undertake a molecular approach to assess specifically how regulation of specific gene sets defines the ecological ‘distinctness’ of these lineages. We propose to focus on the key nutrient regulon of iron (Fe) since this limiting element for primary production in many oceanic environments varies both spatially and temporally with obvious ‘differences’ in more stable oligotrophic open ocean systems compared to more unstable coastal waters. Hence, there is strong reasoning to expect that differences in regulatory capacity exist between lineages occupying contrasting niches, and that such regulatory ‘constraints’, or indeed lack of constraints, facilitate occupation of specific niches (specialists) or overlapping niches (opportunists). Thus, this project will be set out to obtain a comprehensive understanding of the Fe regulon facilitating its acquisition in organisms we consider to be either specialist oligo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Somatic control of primordial germ cell proliferation'.

assistant: **Innovation**

Control of cell proliferation is important during normal growth and, when impaired, might cause malignant transformation. While cell-autonomous control of proliferation has been studied extensively, cell proliferation in the context of a growing organ, when different populations of cells have to coordinate their growth is less well understood. We are using the ovary of the fruit fly Drosophila melanogaster as a model system for understanding how cell proliferation is controlled at the level of the developing organ. The ovary of Drosophila forms during embryogenesis. At the larval stages the somatic cells of the ovary proliferate and differentiate. The somatic niches for germ line stem cells (GSCs) form at that stage. Primordial germ cells (PGCs) also proliferate, and once the somatic niches form, a subset of PGCs become the adult GSCs. Control of PGC proliferation is therefore one of the factors that determine the number of GSCs that the organ will contain. We have performed a screen aimed at finding how PGC proliferation is controlled. Such a screen has not been attempted previously and was therefore likely to reveal novel regulators of cell proliferation. The screen uncovered both cell-autonomous and non-cell autonomous regulators of PGC proliferation. Some of the genes are known cell cycle regulators. Others are homologues of known human tumor-suppressors or oncogenes, which were never studied in the fly. Some of the genes were never shown to control cell proliferation. We propose to study the developmental role of the genes uncovered by the screen. To do so, we will first form a priority list of genes to study according to pre-determined criteria. Our highest priority genes will be those that act from somatic cells to control PGC proliferation. Our studies will prov
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Combining Artificial Intelligence and smart sensing TOward better management and improved quality of LIFE in chronic obstructive pulmonary disease' to be submitted under Horizon Europe.

assistant: **Abstract**

Chronic obstructive pulmonary disease (COPD) is a highly prevalent chronic condition. While COPD is a lung disease, it is mainly the exacerbations and extrapulmonary comorbidities which affect the quality of life, health care costs, and prognosis. The optimal COPD treatment needs to focus on both the characteristics and consequences of the lung disease itself and the diagnosis and treatment of comorbidities. While the severity of lung function impairment is routinely assessed, the exacerbations, the associated comorbidities and limitations in daily life are still significantly underestimated. A personalized approach to COPD management is needed to specifically address the disease, prevent exacerbations, and mitigate its comorbidities to obtain a positive impact on patient health and quality of life. TOLIFE will clinically validate an artificial intelligence (AI) solution to process daily life patient data captured by unobtrusive sensors to enable optimised personalised treatment, assessment of health outcomes and improved quality of life in COPD patients. The TOLIFE approach to COPD management, targeted to predict and mitigate exacerbations and continuously assess the health outcomes, has the potential to reduce mortality, improve health related quality of life and reduce the healthcare costs.TOLIFE will develop and clinically validate an AI-based platform for the early prediction of exacerbations and assessment of the health outcomes. Prediction of exacerbations and assessment of health outcomes will be exploited by clinicians through a patient management tool to perform early and personalized treatment. TOLIFE platform will inform through a disease information tool the patient and caregivers about the patient's health status, the specific treatment plan and lifestyle
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'StructURal and Functional dynamics of BrassIca napus polyploid Genome' (SURFInG), addressing dissemination and exploitation.

assistant: **Impact**

Interspecific hybridization and genome doubling (allopolyploidy) are key factors in plant adaptation and speciation. These intriguing genomic processes cause extensive structural rearrangements and reprogramming of functional regulatory pathways inherited from parental species. Furthermore, hybrid species have shown broad phenotypic diversity. However, mechanisms responsible for genome stabilization after allopolyploidy remain poorly understood. The aim of my project is to provide an interdisciplinary overview of the effects of polyploidy on structural and functional dynamics in a major crop, oilseed rape (Brassica napus). This polyploid species is an excellent system to unravel the long-term and immediate evolutionary effects of ancient and recent polyploid events. In my project, I will use a novel approach that combines (epi)genomics and transcriptomics in phenotypically contrasting polyploids to investigate the role of structural and (epi)genetic regulation in genome stabilization. This work includes, amongst others, the transfer of knowledge to the host lab of cutting-edge molecular and in silico DNA methylation analysis methods. More specifically, I will determine the effects of structural and functional dynamics on B. napus (1) meiotic behavior and fertility, (2) gene expression and (3) glucosinolate content. My findings will open new avenues for using standing variation to modify and ultimately enhance agronomic traits. I have become a recognized evolutionary biologist working at the interface of ecology, genomics and molecular biology. From the expertise of the host lab and availability of technical platforms in situ, I will not only get acquainted with cytogenetics and metabolomics, but will increase my expertise in comparative genomics and in high throughput g
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Commercialization of novel Diagnostic Platform with Synaptic adaptation Arc treatment method for tinnitus patients.' (2014-2020) under Horizon 2020.

assistant: **Objectives**

Meeting demand for the first medical device for diagnosis and therapy of tinnitus is set to be a crucial challenge for future audiology and neurology. For that reason Kinetic Center of Advanced Audiology (www.kinetic-cna.pl/) aims to commercialize technologies for the Tinnitus examination and treatment. To do so, co-founders rely on their extensive experience and the interdisciplinary team of: audiologists, laryngologists, medical technicians, neurobiologists, neuroscientists, musical trainers, hearing care professionals, clinicians and nutritionists.Our main objective today is to bring to the global market a novel “Tinnitus Diagnostic Platform” which is a IT platform of multiple test, that can give more information and indicate with more precision the nature of the tinnitus and  “Synaptic adaptation Arc therapy” which is dedicated for tinnitus patients after sudden hearing loss. We have conducted preliminary research studies on a small group of around 200 patients and the promising results encouraged us to demonstrate clinical effectiveness of our solution on n a bigger number of subjects.The key market application of Tinnitus Diagnostic Platform is to differentiate the pathology of hearing and finally to select appropriate treatment. Synaptic adaptation Arc therapy is based on continuous acoustic stimulation which enforces activity of hear cells and nervous system and gives opportunity to release Arc/Arg 3.1 protein that rebuild synapses. The project addresses the problem of lack of medical device for tinnitus diagnosis and very poor research on the course of the condition.Finally, to fully exploit and to commercialize this new and EU-based technology, we want to open new Advanced Audiology Clinics around Europe to propose complex methods on hearing pathologies. The F
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'WATER AND ENERGY EFFICIENT INDUCTION HUMIDIFICATION SYSTEM FOR TEXTILE APPLICATIONS' (IHS) targeting Horizon 2020.

assistant: **Abstract**

The AERIS Group, is located near Bergamo, Italy and specializes in the design, development, manufacturing and commissioning of air technological applications, ranging from air conditioning  through to removal and heat recovery. With more than 50 years of experience and a turnover of over €6 million in 2016, our group is composed of 3 companies: AERIS air technologies, expert in HVAC and filtering, EDENYA for air cooling solutions and MAZZINIICI, our textile division. The technical know-how of our high-specialized professionals, our detailed knowledge of materials, production processes and production methods in the different industrial fields as well as a business strategy turned towards continuous innovation and global presence are the basis of our success and growth.  We listen carefully to customers feedback from the textile sector – which represents 35% of our turnover – and their concerns about product quality, water and energy consumption. This led us to the development of the patented Supra high pressure water technology 20 years ago. We are now developing the next step, the Induction Humidification System (IHS): by integrating a customized air distribution and diffusion system with specific diffusers, we can “move” a volume of air 10 times equal to the primary air, and fully mixed with micronized water for even humidity level without water waste. The IHS reduces drastically water consumption by 65% and energy by up to 80%, while guaranteeing an optimum control of humidity (+/-0.5%) and temperature (+/- 0.5 degrees).  The IHS system will achieve long-term profitability for both our customers and our company, with an increase of sales reaching € 36 millions, profit for € 8.7 millions and 31 new employees by 2024.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Entropically programmable DNA-based bioSensors for personalized medicine' to be submitted under Horizon 2020.

assistant: **Abstract**

My proposed program consists in a 2-year research activity at the forefront of bioengineering, aiming at the development of Entropically programmable DNA-based bioSensors for high-precision medicine (Entropic DNA Sensors). Biosensors have achieved a significant feat in bioanalytical chemistry and translational science: high-frequency, real-time and quantitative measurements of clinically relevant molecules in vitro, and in vivo. Despite their advantages, our ability to precisely control and regulate the binding activity of their bioreceptors (i.e., the recognition element) still represents a highly relevant bioengineering challenge and limitation. Indeed, the fully control of bioreceptor’s binding properties would allow the design of new biosensors with improved and predictable analytical performance. In Entropic DNA Sensors I propose a multidisciplinary, innovative, and versatile approach based on a purely naturally inspired entropic allostery mechanism which allows to finely tune the activity and the response of synthetic bioreceptors. Specifically, my goal is to further explore our ability to rationally design intrinsically disordered domains into classic DNA-based bioreceptors so as to improve their useful dynamic range. Then, I will adapt these intrinsically disordered bioreceptors into an electrochemical read-out modality that supports the real-time, multi-hour, high-frequency, calibration-free measurements of clinically relevant molecules (i.e., doxorubicin, glucose, phenylalanie) directly in complex biological fluids in vitro. Finally, I will test them in simulated clinical scenarios to demonstrate their ability to reach personalized medicine. To achieve this goal I will leverage my experience in In vivo biosensing and Point-of-care (PoC) testing technologies wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Loops and groups: Geodesics, moduli spaces, and infinite discrete groups via string topology and homological stability' (2014-2020) under Horizon 2020.

assistant: **Objectives**

This proposal lies at the intersection of algebra, topology, and geometry, with the scientific goal of answering central questions about homological stability, geodesics on manifolds, and the moduli space of Riemann surfaces. Homological stability is a subject that has seen spectacular progress in recent years, and recent work of the PI has opened up new perspectives on this field, through, among other things, associating a canonical family of spaces to any stability problem. The first two goals of the proposal are to give conditions under which this family of spaces is highly connected, and to use this to prove homological and representation stability theorems, with determination of the stable homology. Particular attention is given to Thompson-like groups, building on a recent breakthrough of the PI with Szymik. The last two goals concern geodesics and moduli spaces via string topology: The third goal seeks a geometric construction of compactified string topology, which we propose to use to address counting problems for geodesics on manifolds. Finally our fourth goal is to use compactified string topology to study the harmonic compactification itself, and give a new approach to finding families of unstable homology classes in the moduli space of Riemann surfaces. The feasibility of the last goals is demonstrated by the PIs earlier algebraic work in this direction; the proposal is to incorporate geometry in a much more fundamental way. The project combines breakthrough methods from homotopy theory with methods from algebraic, differential and geometric topology. Some of the goals are high risk, but we note that in those cases even partial results will be of significant interest. The PI has a proven track record at the international forefront of research, and as a resea
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Development of Innovative Particleboard Panels for a better mechanical performance and a lower environmental impact' under Sixth Framework.

assistant: **Concept**

European furniture industry is largely made by SMEs. In modern furniture industry use of particle-board (chipboard panels) is continuously growing. They are basically composite materials, usually wood chips and a binder (adhesive or resin). During the last decade, especially in countries where forestry resources are scarce, there has been a decay of mechanical performance of chipboard panels; main reason for that is the increased use of recycled materials obtained from old pieces of furniture, made themselves of chipboards, for the preparation of new chipboard panels, instead of natural wood chips. This downgrading of performance is causing serious problems to furniture manufacturers, typically SMEs, across Europe and motivate this Collective Research project proposal, which aims at reinforcing the technological basis of chipboard manufacturing, and at developing innovative chipboards, which meet mechanical performance requirements and have a reduced environmental impact. SMEs involved in this project are coming from the following sectors mostly at the end of the furniture industry value chain:a) SMEs manufacturers of furniture;b) SMEs manufacturers of semi-finished panels for the furniture sector.Recycling in particleboard industry has an increased relevance, also because of environmental impact.The demand from furniture manufacturers is clearly oriented towards innovative particleboards, employing new materials. This project will bring:a) Improved mechanical performance of particleboards in terms of:b) Reduced density;c) Increased stiffnessd) Improved workabilitye) Lower environmental impact.Innovation will concern the following aspects of particleboard composition and manufacturing:a) Innovative binder materials b) Recycling waste materials as filler for particleboar