RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'MiRNAs as therapeutics for neurorepair in Multiple Sclerosis' (MiRepair).

assistant: **Innovation**

I hope to embark my first post-doctoral position, as a MSCA fellow, to identify microRNAs (miRNAs) involved in demyelination/remyelination processes with the final intention of modulating their expression as a therapeutic tool to promote neurorepair in multiple sclerosis (MS). MS is a chronic neurological disease of the central nervous system characterised by primary demyelination. All current disease-modifying therapies are unable to induce neurorepair and to prevent the progressive accumulation of disability from neuronal damage. miRNAs are one epigenetic mechanism involved in the genes-environment interaction that produces the pathology and symptoms in MS. My thesis project consists of describing miRNAs profiles in cerebrospinal fluid and serum of MS patients to exploit their potential role as clinical biomarkers. This project will combine these human miRNA data with robust experimental models in order to identify miRNAs involved in the damage and endogenous repair associated with MS. I will employ ex vivo models to study the biological role of miRNAs during these processes and how their manipulation might enhance neurorepair. The use of hydrogel-scaffolds in combination with miRNA modulators to enhance remyelination will be studied and preclinical MS in vivo models will be used to assess their therapeutic potential. I will work at the “microRNA Inflammation Group” in the Royal College of Surgeons in Ireland (RCSI) under mentorship of Dr Claire McCoy, a leader of MS research in Ireland. Two secondments have been planned in the National University of Ireland, Galway (NUIG) and Queen’s University Belfast (QUB). This fellowship will enable me to upskill in research techniques and expand my transferable skills and competences for a career path for academia or industry in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'A META OPERATING SYSTEM FOR BROKERING HYPER-DISTRIBUTED APPLICATIONS ON CLOUD COMPUTING CONTINUUMS' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

NebulOus will accomplish substantial research contributions in the realms of cloud and fog computing brokerage by introducing advanced methods and tools for enabling secure and optimal application provisioning and reconfiguration over the cloud computing continuum. NebulOus will develop a novel Meta Operating System and platform for enabling transient fog brokerage ecosystems that seamlessly exploit edge and fog nodes, in conjunction with multi-cloud resources, to cope with the requirements posed by low latency applications. The envisaged BRONCO solution includes the following main directions of work: i.Development of appropriate modelling methods and tools for describing the cloud computing continuum, application requirements, and data streams; these methods and tools will be used for assuring the QoS of the provisioned brokered services. ii.Efficient comparison of available offerings, using appropriate multi-criteria decision-making methods that are able to consider all dimensions of consumer requirements. iii.Intelligent applications, workflows and data streams management in the cloud computing continuum.iv.Addressing in a unified manner the security aspects emerging in of transient cloud computing continuums (e.g., access control, secure network overlay etc.). v.Conducting and monitoring smart contracts-based service level agreements.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Green Vehicle Index Project' (GVI), addressing dissemination and exploitation.

assistant: **Impact**

The GVI results will empower the consumer and strengthen the demand side. This will be achieved by informing the consumers through the involved (inter)national consumer organisation and the strong link to Euro NCAP. This GVI project will be the catalyst and initiator for a fully-fledged Green NCAP program, which will help consumers, authorities and all other stakeholders to identify if a vehicle truly is clean and energy efficient.GVI’s vision is:  ‘The highest standard is attributed to a car that maximises the reduction of its own pollutants and greenhouse gasses and, at the same time, operates at minimised fossil fuel consumption and/or maximised energy efficiency under real-world conditions during its life time.’The GVI project will independently assess the full environmental performance of a vehicle in the most comprehensive manner. It is of paramount importance that complex test procedures and results are converted into independent, meaningful and comprehensive information for consumers that can easily be understood. - To develop a holistic assessment methodology of a vehicle’s environmental performance over the vehicle’s useful life - including a complete set of test protocols and test procedures with the aim to independently test vehicles and assess the full environmental performance;- To develop an independent rating system based on developed testing protocols, for the assessment of new vehicles’ performance across multiple criteria (real world fuel consumption, noise, cost );- To validate the overall methodology by conducting real world and laboratory testing and publish results of the 49 most readily available low emitting vehicles in the market;- Improve the administrative and contractual conditions to run the vehicle environmental performance assessment prog
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Stem cells for Biological Assays of Novel drugs and prediCtive toxiCology (StemBANCC)' under Seventh Framework.

assistant: **Concept**

StemBANCC, comprising internationally renowned investigators, is ideally positioned to deliver a unique European biorepository and drug discovery pipeline based upon human induced pluripotent stem cells (hiPSC). This unrivalled opportunity will address the pressing therapeutic need in neurodegeneration, neurodysfunction and diabetes. We have immediate access to richly phenotyped subjects with a wealth of clinical data. Furthermore our cohorts include genetic and genome data, allowing us to carefully select subjects for hiPSC based disease model development. This clinical-genetic stratification is essential to ensure that cellular models display disease and therapy relevant phenotypes. hiPSC reprogramming is undertaken by an internationally respected centre, providing robust, reliable and timely delivery of hiPSCs; ensures the biorepository only houses quality assured hiPSC lines; and reduces unwanted variability in assays. We have leading experts in hiPSC differentiation, providing protocols with over 99% efficiency in producing cortical excitatory neurons and cardiomyocytes, which following up-scaling will meet demands of high throughput assays. StemBANCC will deliver a comprehensive ‘omics’ dataset on over 1500 stem cell lines. This includes cells taken at different lineage stages, after therapeutic challenge, monogenic and complex variants, and with matched isogenic controls. The integration of this network/pathway data will define core etiopathological processes, therapeutic generality, reveal on- and off-target effects, allow candidate therapeutic repositioning and decouple tolerance and toxicity pathways. The large-scale integrated datasets then directly guide the disease specific targeted assays, designed to maximize utility in low and high- through compound scre
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'DEMONSTRATION OF ULTRA-LOW POWER WIRELESS SENSOR NETWORK FOR METERING APPLICATIONS'.

assistant: **Objectives**

The SYNCSEN Demonstration action (DEMOSYNCSEN) is a direct follow-on of the very successful SYNCSEN FP7-SME-2007-1 ‘Research for SME’s’ project (Grant Agreement number: 222322) that came to a successful conclusion in January 2011. The RTD tasks of the SYNCSEN project resulted in an Automatic Metering Reading (AMR) system that included smart meters (Hardware and Software) and a collection system (network protocols and algorithms). The system has been tested in a controlled real case scenario. However, further verifications and minor improvements need to be done before entering the market. The main purpose of this project is to share common resources amongst the consortium partners to validate that the RTD technology created in SYNCSEN can be launched into the water utility market. The project aims to bridge the gap between the research results and the final marketable product; with focus on the specific necessities of the European water utilities sector and adding new business opportunities to this market.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'sustainable HYdrogen powered Shipping' (2021-2027) targeting Horizon Europe.

assistant: **Abstract**

The general objective of sHYpS is to support the decarbonisation of the shipping industry, by leveraging on previous and on-going work and investment made by Viking and some consortium members. It will develop a hydrogen-based solution, which can be adapted to multiple types of vessels and in some cases can already achieve IMO’s target for 2030 and 2050.The project will develop a (i) novel hydrogen storage intermodal 45’ ISO c-type container, (ii) the complete detailed design of  modular containerised  powertrain based on optimised PEM Fuel Cells and  (iii) their dedicated logistics. On one hand the project will define a logistic based on swapping pre-filled containers, on the other hand it will define a perspective scale-up of the storage capacity and the supply applied to the Port of Bergen use-case. This will allow to kick start a supply-chain without waiting for the full infrastructure to be in place. We show how this approach can already support a remarkable part of the vessels in the EU waters. The project will use the window of opportunity of 1 Viking’s newbuilds Ocean Cruise vessel to install the storage system onboard with the complete gas handling and energy management system and test it during the shakedown cruise by 2026, with a limited power Fuel Cell. When the 6MW will be in place (pendent investment decision by Viking) this will allow to cut 50% of emissions in a 14 days fjord cruise. The midterm outcomes are remarkable, since Viking has a building program of 6 Ocean Cruise ships by 2030 and several river ships. With the right logistics in place the ISO container technology can develop in hundreds of units per year. In the meantime, the upscaled design of the container from this project will approach more segments in sea and IWW application and look to hu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for ''Marriage and Cultural Diversity in the German Empire'' in the context of a Horizon 2020 call.

assistant: **Objectives**

How do putatively universalistic norms with global reach relate to politics of diversity and pluralism within national societies? By assessing the legal regulation of marriage and the family, ‘Marriage and Cultural Diversity in the German Empire’ (MARDIV) will advance significantly our understanding of the global diffusion of legal and social norms. The tension between global norms and cultural specificity has come to a head during the first decade of the 21st century. Not only has the presence of Muslim immigrants raised the profile of debates over the diversity of personal status law throughout Europe. The legalisation of same-sex marriage in many European countries has also pointed to a seachange in public views about the family and the role of the state in preserving it. How do legal transplants operate in family law? Can we discern particular patterns of diffusion in specific historical circumstances? And, how do 19th- and early 20th-century developments in family law remain relevant today? MARDIV addresses these questions by scrutinizing the historical roots of recent debates. 19th- and early 20th-century Germany offers a particularly relevant case study because it was a laboratory of both modernity and cultural diversity in which questions of global reach, national identity, regional particularity and local traditions came into especially sharp relief. MARDIV suggests that an understanding of Germany’s past experiences can enable us to better analyse Europe’s present. To this end, the project employs an innovative interdisciplinary methodology linking history and sociology and a novel theoretical framework. The main empirical aims are twofold: to shed light on the historical roots of contemporary European debates about the family, and to reflect on broader proces
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The Making of the Earth – Reading the Geochemical Code from Meteorites and the Earth’s Oldest Rocks' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

It is still an open question how Earth became the rocky habitable planet as we know it today. This is because there is a significant time gap of several 100 million years between Earth’s oldest rock archives (ca. 4 billion years old) and most extraterrestrial samples like meteorites that archive the birth of our solar system ca. 4.5 billion years ago. Within this time gap, three key processes that shaped our planet took place, i.e., Earth’s growth via asteroidal collisions, formation of the metal core and a first solid crust, and the delivery of volatiles such as water. Because rock samples are lacking, these fundamental processes have to be traced indirectly, by using highly sophisticated geochemical tools like isotope or trace element compositions of younger rocks or meteorites. With this proposal, I plan to better unravel Earth’s earliest history and better identify its building blocks, by combining the geochemical record locked in Earth`s oldest rocks and extraterrestrial samples. The ground breaking nature of this work is the development of new geochemical techniques that are way beyond the current state of art, and many of them will be applied at an unprecedented level of sensitivity and precision. I will cover three linked approaches, namely high precision analyses of (i) nucleosynthetic isotope anomalies, (ii) radiogenic isotopes and (iii) trace elements. To better constrain the history of volatile delivery to the nascent Earth, a focus will be on comparing the geochemical record provided by refractory and volatile elements. In their synergy, the results will provide a major advance in unravelling Earth’s earliest history.INFANTEARTH builds on high profile research strengths of our group, where a unique pool of collaborating scientists and analytical equipment a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Seminal Sufism in Motion: The Oldest Extant Arabic Encyclopedia of Islamic Mysticism and its Dissemination' (SEMENSUF) under Horizon Europe.

assistant: **Objectives**

SEMENSUF is an interdisciplinary and collaborative project at the crossroads of philology, intellectual history, and material culture that adopts basic tools of digital humanities for Arabic literary and religious studies. It aims at providing an open-access scholarly edition and lucid, knowledge-sharing English annotated translation of the oldest extant encyclopaedia of Islamic Mysticism, the Book of Flashes in Sufism by Abū Nasr al-Sarrāj (d. 988). Through its innovative method, SEMENSUF aims at laying the foundations for a new historical and textual approach to the editing of early Sufi sources: the philological atomization of the work in textual units, the study of the manuscript transmission and material culture, and the digitization of later related sources are critical for shedding light on channels of knowledge transmission, centers of learning, and scholarly networks in early Sufism and more broadly in Islamic culture.SEMENSUF strongly believes that editing and translating a 1000-year-old work of mysticism can have a major impact on European multicultural and multifaith societies. In fact, the Book of Flashes tackles several intra- and extra Islamic issues that are still very much relevant to today’s Europe: it highlights how mysticism is and should be considered a genuinely component of Islam, invalidating most contemporary Neo-Salafi claims to the contrary; more importantly, the Book of Flashes reflects a strong concern for and appraisal of heterogeneity and pluralism within Islam. It is a hymn to diversity and to coexistence of different practices and sensibilities which collaborate rather than compete, resulting in a shared spirituality. SEMENSUF thus aims at having an impact on European pluralistic society by making available, to a wide audience, a univers
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'HIGHER: “High performance Engine for Light Sport Aircraft' (HIGHER), addressing dissemination and exploitation.

assistant: **Impact**

HIGHER project will launch on the aviation market an innovative engine which will contribute to make small aircrafts and helicopters individual, diffused, sustainable and safe transport vehicles.In order to reach this goal, the new engine conceived by Egimotors will ensure: - higher performance, thanks to the weight containment between 105 and 115 kg (20% lower than the average of the engines of the same power available today) coupled to an output of 200 hp and to a 4 valves-per-cylinder system that delivers high performance;- lower purchase cost, thanks to simple design, limited dimensions and weight, and multiple potential applications with consequent advantages in construction costs that allow a lower retail price;- lower operating costs, thanks to the possibility to use (in addition to AvGas) also MoGas (Automotive fuel) characterized by significantly lower cost. The study of thermodynamics matched to the geometry of the cylinder ducts was also designed to ensure a reduction of fuel consumption;- higher reliability and safety, thanks to high-quality construction component, technical processes choices and careful assembly. EGM 4x4 mechanical components are less stressed and consequently have longer service life. The electronic ignition and injection system, completely redundant and validated by extensive bench tests, also ensures high reliability;- lower environmental impact, thanks to in-depth study of the intake and exhaust gas system, which will be able to reduce fuel consumption and consequently pollution. In terms of business plan, the company strategy aims at selling in 5 years more then 500 engines, at a target price of 16,000 euro, with a turnover of about 3 millions per year since 2021 and a market share of 7%.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Information tools for more efficient forestry-wood chains.' (INFORCHAIN) targeting Fifth Framework.

assistant: **Abstract**

The Forestry Wood Chain consists of forest owners, machine entrepreneurs, wood- procurement organizations, sawmills and pulp paper mills linked together through a complex production and business network. Efficient and market driven operations within this network are vitally important, particularly in the face of increasing international competition. There is a strong demand from the industry for the. Development of fast and accurate information flows between all the actors in the FWC. The rapid advances in information technology (e.g. Internet and wireless telecommunication) offer new opportunities to improve information management and decision support in the FWC. The overall objective of this project is to increase the competitiveness, employment and environmental concerns of the European FWC through application of these new technical opportunities to improve information flows and decision support.