RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Influence of Climate variability on the Gravettian cultural Diversity and Evolution' to be submitted under Horizon Europe.

assistant: **Abstract**

Currently facing major environmental changes due to global warming, a growing concern of modern societies is related to how we will be able to cope with these rapid changes to survive. This kind of preoccupation is probably not new: over the course of its history, the human species has been able to adapt to very different environmental conditions thanks to diversified cultural adaptations. The objective of the project ClimDivE is to understand the role of environmental change in the diversity and evolution of cultural adaptations at large geographic and chronological scales, using the archaeological record of the Gravettian (32-26 000 years before present) as an example framework. At this period, archaeologists have shown that two neighboring regions, Western and Central Europe, exhibit very different cultural trajectories, without being able to understand the large-scale mechanism that influenced this pattern. The ClimDivE project aims to explore the factors composing this mechanism by integrating archaeological data and paleoclimate simulations into a unified approach: Eco-cultural niche modeling. This approach derived from the field of distributional ecology allows one to identify the environmental conditions associated with specific cultural traits. To do so, Dr. Vignoles will gather pertinent archaeological occurrences and environmental variables for the Central European Gravettian. These data will feed a mathematical model that represents the niche. These results will be compared with her previous work on the Western European Gravettian. Based at Lige with shorter stays in Kansas University and Paris-Saclay, the research will be supervised by three internationally recognized researchers specialized in the Gravettian, ecology and paleoclimatology. The proposal will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'A novel role of small RNA pathways in regulating DNA replication in polyploid cells.' (2021-2027), addressing dissemination and exploitation.

assistant: **Impact**

Small RNA-mediated gene regulation and DNA replication are fundamental genome-regulatory pathways essential for cellular life, organismal development, and disease prevention. While small RNA pathways are known to sequence-specifically regulate DNA copy number in some unicellular animals, such connections have yet to be found in multicellular animals. With this project, I will investigate and mechanistically characterize such a potential connection in the Drosophila animal model system. Piwi-interacting RNAs (piRNAs), a class of animal small RNAs, safeguard the germline genome against repetitive DNA proliferation by guiding repressive heterochromatin formation at target loci. In Drosophila melanogaster ovarian nurse cells, heterochromatic (peri)centromeric DNA repeats undergo selective local suppression of DNA replication thus lowering their relative copy number. Interestingly, abundant piRNAs able to target to these 'underreplicated' regions have been found, yet the potential functional interactions between small RNA genome defense and DNA replication remain unexplored. With this project, I will bridge this gap by investigating the role of satellite piRNAs in Drosophila melanogaster, focusing on the interplay between regulated DNA replication and small RNA genome defense. Two interconnected hypotheses will be examined: (1) piRNA-directed heterochromatin formation regulates centromeric DNA copy number, and (2) piRNA-regulated heterochromatin sinks alter epigenetic inheritance. To do so, I will apply advanced sequencing- and imaging-based methods for DNA copy number quantification and leverage the powerful Drosophila genetics to uncover underlying molecular mechanisms.In sum, my investigation of small RNA-based regulation of DNA replication holds the promise to reveal a n
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'High performing batteries for accelerated uptake of hybrid and electric vehicles' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Air pollution derived from transport is a major problem for cities in Europe and worldwide. Traffic congestion already stifles about 2% of the global GDP each year and this negative trend is set to continue due to the exponential growth of urban population. Hybrid and Electric vehicles (H&EVs) are a key component of the overall transport solution. However e-mobility still presents many drawbacks, the main ones being the price and range of electric vehicles which are reliant on optimal battery technologies.The BATTERY+ project aims to bring into the market the next generation of high performing Li-ion battery solutions for e-mobility that goes beyond the existing state-of-the art. This claim is sustained by: its proven energy density (leading to more range and less weight); the most accurate State-of-Charge monitoring system (reducing users’ anxiety for sudden changes in range); and the support of an advanced remote system for remote battery monitoring, diagnosis and driving advice. The batteries will be on average 30% more durable, leading to significant cost-efficiencies for both EV manufacturers as well as end-users. Initially targeting Light Electric Vehicles (LEVs) and Heavy Duty Electric Vehicles (HDEVs), in time, the technology has the potential to be deployed in electric vehicles of all sizes as well as in any battery-powered appliances.The company behind the project is MILLOR, a young SME specialised in the design, development and manufacturing of high added value battery solutions. In just a few years of existence, the company has managed to position itself as a key innovator in battery technology in Spain and has also tied links with key partners in Europe and Asia. The management of the company sees the BATTERY+ project as its springboard to accelerate its gr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'VALIDATION OF A MULTIMEDIA TITLE SERIES PRODUCTION METHODOLOGY' (VALMMETH).

assistant: **Concept**

This project aimed to transfer advanced tools for the production of Multimedia Titles in Series (MULTIS) from the Co-ordinator, the Computer Technology Institute of Greece (CTI), to four publishing companies. A Title Series is a set of multimedia titles with comparable content and structure: a series can consist of titles as similar as quarterly updates of a product catalogue or as diverse as presentations of different companies. All titles in each series come under the generic description of the Titles Series, given as a Model Title Specification. This technology allows software engineers to design systems, which will allow non-specialists to produce multimedia titles" relatively simply. The Model Title Specification initially embodies just the ideas and creativity of its designer - normally the Series Director who is not a computer professional. It is then transformed by Software Engineers using the MULTIS tools, into a computer-based production environment - a title editor and database. In this MULTIS environment, less qualified personnel fill in the content, edit, test and produce the various titles in the series. As a result of the MULTIS methodology, both time and cost can be reduced, expensive and scarce personnel, namely the director and the computer engineers, are only employed where they are needed and the publisher can then set up low-cost high quality production lines for a multitude of titles.The outputs of the project were four MULTIS systems in four publishers operating in the subject areas of foreign language training, web based company presentations, tourism and medical training. Each of these in turn had produced one or more multimedia series. The MULTIS system was shown to be transferrable and by the end of the project in early 1999, CTI intended to s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Investigation for woven fabrics synthesis, weaving and treatment to optimize the resistance to weather conditions and solar radiation' in the context of a Fifth Framework call.

assistant: **Objectives**

Woven textile fabrics are used for tents and summer umbrellas for protection against the sun. It is well known the continuously increased problem of the ozone depletion and the high ultraviolet radiation (UVR), which is extremely harmful for the human health. This project will constitute towards the production of more safe and effective textile products to solar radiation and weather conditions. The wide production of these products will make European Textile and Clothing Companies more competitive and so they will increase their sales. Main goals of these projects are also the institution of a standard method for the creation of an indicator of sun protection and of a proposed Quality Label. So this project will support the sustainable growth of the Textile and Clothing Industry. Especially for the Trade Balance this effort must be continuous with Textile and Clothing products with sophisticated properties and new design and so it will be possible to minimize imports and to increase exports especially in the World Market, which always needs better, smarter and safer textiles.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'MechANIsms and actors of Feasible Energy Transitions'.

assistant: **Innovation**

The technologies needed to decarbonize the electricity system are already commercially available. There are mathematical models of how these technologies can be deployed sufficiently fast and at a large enough scale to displace fossil fuels to meet climate targets. Yet there is no scientific method to evaluate whether these scenarios are feasible given the real world’s socio-political constraints.  MANIFEST develops a new scientific understanding of socio-political feasibility of climate change mitigation that takes into account the context, actors and change over time. Theoretically, MANIFEST combines a definition of socio-political feasibility from political philosophy with the concept of causal mechanisms of energy transitions. Thus, I shift the thinking about the feasibility of climate change mitigation from its current focus on barriers and enablers to a dynamic and context sensitive view with space for actors and agency. Empirically, I focus on transitions in electricity supply including the expansion of low-carbon electricity and coal phase-out. I explore three areas which are critical for the feasibility of decarbonisation of electricity: (i) the role and capacities of international suppliers of electricity technologies, (ii) the competition between electricity technologies at the early stages of their introduction in emerging economies, and (iii) factors shaping the growth of low-carbon technologies and under what conditions they substitute carbon-intensive ones. Methodologically, I develop a new approach to assess the feasibility of climate solutions by constructing dynamic feasibility spaces which are a function of paths, contexts and actors. I test this approach by analysing national low-carbon electricity targets to determine whether states plan to accelera
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Investigating the role of p63 in PROstate STem cells and tUMOR development' (2007-2013) under Seventh Framework.

assistant: **Objectives**

Cancer results from genetic and epigenetic changes that cause uncontrolled proliferation of cells. Central to this process are changes in the expression of tumor suppressor genes or oncogenes. P53 is one of the best-characterized tumor suppressor genes, whose expression is lost or mutated in approximately 50% of human cancers. P63 is a member of the p53 gene family that plays critical roles in epithelial cell proliferation and homeostasis, through regulation of cellular senescence and stem cell renewal. However the role of p63 during tumor development is unclear, with both tumor suppressive and oncogenic roles attributed. The p63 protein is overexpressed in many tumors, particularly squamous cell carcinoma of the skin and lungs. However, p63 expression is lost during the development of adenocarcinoma of the prostate and breast. The work outlined in this proposal aims to determine the role of p63 in the prostate gland, particularly in prostate stem cells, and during development of prostate tumors, using a combination of cell and molecular biology, 3D tissue culture and prostate-specific mouse models. The expression pattern of the six different isoforms of p63 will be determined in the normal prostate gland and in prostate stem cells. Loss-of-function studies will be performed in vivo to address the role of p63 in the prostate gland. Using prostate-specific mouse models, p63 will be ablated in the normal prostate gland and during prostate tumor development. The effects of loss of p63 on prostate stem cell proliferation, prostate tumor initiation, maintenance and metastasis will be examined. High-throughput genomic screens will also be performed to identify novel p63-target genes in the prostate gland and to determine the functions of these genes in stem cell proliferation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'INvention of SCRIpts and their BEginnings' (INSCRIBE) under Horizon 2020.

assistant: **Objectives**

Writing must rank among mankind’s highest achievements. Yet the factors that enabled its invention independently in different parts of the world have never been subject to an analysis from a multidisciplinary and comparative perspective that encompasses both deciphered and undeciphered scripts. INSCRIBE takes such an approach, combining a study of the world’s first instances of writing, including the earliest in Europe, through the lens of archaeology, anthropology, cultural evolution, cognitive studies and decipherment strategies. This methodology involves three strands of research.First, it will consider the original inventions, all of which are image-based, from Mesopotamia, Egypt, Mesoamerica and China, and other debated cases. The objective is to characterize their conception in terms of visual cognition (why are signs shaped as they are?), archaeological setting (what are the contextual preconditions, why does writing emerge when it does, and only four times in history?), application of use (what are its initial purposes?), and language notation (what are the paths to registering sound?).Second, it will explore the earliest scripts in Europe from the second millennium BC Aegean, whose initial phase is highly iconic. The three undeciphered Aegean scripts (Cretan Hieroglyphic, Linear A and Cypro-Minoan) will be analyzed for the first time from a multistranded perspective that will shed unprecedented light on their creation and development. The objective is to analyze the relationship between these scripts and to apply a multi-stepped (and already successfully piloted) decipherment strategy. Third, INSCRIBE proposes to go beyond the traditional standards applied to the corpora of inscriptions by producing the first complete digital corpus of all three Aegean undeciph
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Scaling up Co-creation: Avenues and Limits for Integrating Society in Science and Innovation'.

assistant: **Concept**

Co-creation practice – and co-creation research – are at a crossroads: More than ever, initiatives to boost innovation through collaboration among diverse actors are flourishing across Europe. Yet, this mainstreaming poses new challenges to better understand “co-creation processes and outcomes under various cultural, societal and regulatory backgrounds to allow better-targeted policy support” (SwafS-13-17). To date, no systematic studies exist that detail how co-creation instruments operate under different socio-cultural conditions, i.e. if “best practices” will be effective elsewhere or if the resulting products and services are compatible with new markets.SCALINGS addresses the challenge of mainstreaming co-creation across a diverse Europe head-on: In the first ever rigorous comparative study, we will investigate the implementation, uptake, and outcomes of three co-creation instruments (public procurement of innovation, co-creation facilities, and living labs) in two technical domains (robotics and urban energy) across 10 countries. Using comparative case studies and coordinated cross-country experiments, we explore if and how these instruments can be generalized, transferred, or scaled up to new socio-cultural, economic, or institutional conditions to unleash their innovative power. Based on this unique data set, we will develop two new transformative frameworks – “situated co-creation” and “socially robust scaling” – to guide the wider dissemination of co-creation. We will synthesize our findings into an “EU Policy Roadmap” to support ongoing EU innovation policy efforts. Empirically, SCALINGS is closely integrated with over two dozen European co-creation initiatives that deal with cross-cultural transferability on a daily basis. Together with these partners, we wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'ON BOARD FUNCTIONAL VALIDATION ON THE MADRID-SEVILLA LINE' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

The objective of the EMSET project is to perform the preparatory activities conducive to a full-scale functional validation of the on-board European Rail Traffic Management System (ERTMS) sub-system. Such validation includes the interoperability tests via several external STMs (Specific Transmission Modules) - with some main existing signalling systems used in Europe.The project is organized in several tasks dealing with all the relevant aspects of the functional and interoperability test activities which are to be carried out both in laboratory and on the Madrid-Seville line. The overall workplan consists of five main tasks as follows:Step 1: Elaboration of the test plan and customization of the Users test specifications. Customization of the test track and rolling stock to be used for the tests.Step 2: Development of the tools for the site tests and performance of the sub-system and system integration tests in laboratory Step 3: Functional validation of the ERTMS on-board architecture on full-scale site tests for levels 1 and 2 in the emulation of radio.Step 4: Development of tools (external STMs) for the interoperability test with the national existing systems.Step 5: Performance of interoperability tests via external STMs connected to the on on-board prototypes with different national signalling systems and their evaluation.Only the first three tasks are covered under this research contract subsequent tasks are to be included in an additional contract to be partly funded by the Trans European Network funds. %To fulfil the interoperability requirements for the High-Speed European Rail Network, according with the relevant Directive 96/48/EC.Speedline Madrid-Sevilla %Trans European Network policy Other 4FP projects: ERTMS-EUROSIG, ETCS-VB, MORANE, ERTMS-EEIG Users Dire