RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Improvement of prevention, diagnosis and treatment of sarcoidosis and crohn 's disease.', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

Acidosis and Cohn 's disease are degenerative diseases of unknownetiology, receiving less attention. Lack of conclusive evidence on the implication of mycobacterium to the aetiology of both diseases, lack of a standard method frothier diagnosis and lack of evidence connecting test results, treatment and follow-up, are causing serious problems in prevention, diagnosis and treatment resulting in several thousand cases of deaths and deficiencies all over the world. The central objective of this project is to exploit the etui- pathology of acidosis and Cohn 's disease under the light of mycobacterium implication and improve prevention, diagnosis and treatment. These will be achieved by producing standard procedure for the diagnostic and epidemiological investigation of both diseases, by establishing in a conclusive manner the role of mycobacterium in their pathogenesis, and by combining patient test-result patterns to treatment response.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Smart Coordination Polymers with Compartmentalized Pockets for Adaptive Guest Entrance' (S-CAGE).

assistant: **Innovation**

The S-CAGE project aims to develop a new generation of crystalline solids with periodically-organized discrete voids, or compartments, that would benefit from the combination of the high stability and robustness of dense materials with the structural diversity and versatility (and therefore large applicability) of open frameworks. These coordination polymers (CPs) will be capable of interacting with guest species in the absence of large channels or permanent pores due to the presence of dynamic entrances. This could open new horizons towards the design of unprecedented materials as an enhanced interplay between the guests and the frameworks will be achieved resulting from the confined space of the compartmentalized pockets.The main goals of S-CAGE will be:i) Chemical design of compartmentalized 1D, 2D and 3D coordination polymers. These materials will be designed in such a way that they will provide ideal room to accommodate different guest molecules, which can be easily tuned depending on the target guest.ii) Advanced structural characterization, including modern diffraction studies under pressure of gas and volatile guests. This strategy will provide unequivocal prove of the location of the guest molecules in the internal voids and gain insights of the mechanism of entrance. The direct visualization of the modes of interactions of different gases will permit a deep comprehension of the nature of their interaction.iii) Gas separation studies. My goal will be the development of materials that could specially serve for gas separation and improve the performances of zeolites and MOFs by implementation of dynamic entities into the framework.iv) Sensing capabilities through changes in magnetic properties. The chemical design followed in S-CAGE will result in magnetic CPs wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Emerging communities for collective innovation: ICT Operational tool and supporting methodologies for SME Associations' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The pace of technological change is accelerating. Radical discontinuities seem to happen more frequently. This means that the useful lifespan of knowledge and capability is becoming shorter and that the obsolescence of knowledge/capability is increasingly the norm in innovation. For incremental innovation, specialisation is a winning strategy, but radical innovation requires an interdisciplinary approach and a diversity of knowledge base that in general SMEs struggle to access. COLLECTIVE aims at solving the major constraints of SMEs innovation (to achieve successful, repeated organizational innovation; access to learning and knowledge processing; access to cognitive diversity; have the possibility to be connected to foster collaborative projects) by feeding the innovation ecosystem, basing on 3 key-concepts: (a)communities become the new organisational unit of the innovation process and define the ecosystem of innovation; (b) generation of innovative ideas, new product development and diffusion of innovations are carried out in parallel by self-organising communities of different actors (i.e.: customers, suppliers, users, experts, social stakeholders); (c) the key aspect that will define success or failure in discontinuous innovation projects will be the amount of cognitive diversity that firms (or groups of) will be able to gather and manage. iCOMMUNITY ICT operational platform will be the backbone of this innovation ecosystem and will let SMEs and SMEAGs: (1) identify future emergent technological and economic trends/discontinuities by developing network-based approaches to early detect ‘weak signals’; (2) manage distributed intelligence and creativity in the process of new product development in order to individuate new product ideas and related business models; (3)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Interactive Media with Personal Networked Devices' to be submitted under Sixth Framework.

assistant: **Abstract**

There have been considerable efforts to have Audio Video systems and applications converge, in particular in home environments with homes as spaces of convergence, and for nomadic users with advanced mobile devices as points of convergence. These trends are important but also have limitations that we seek to address and overcome: home-centric systems fail to account for increased mobility and the desire to provide continuous service across spatial boundaries such as the home; device-centric convergence, e.g. in 3G phones, supports nomadic use but provides a very limited user experience as no single device and interface will fit many different applications well. In this NoE we seek to progress beyond home- and device-centric convergence toward truly user-centric convergence of multimedia. Our vision is The User as Multimedia Central: the user as the point at which services (multimedia applications) and the means for interacting with them (devices and interfaces) converge. Key to our vision is that users are provided with a personalised interface and with personalised content independently of the particular set of physical devices they have available for interaction (on the body, or in their environment), and independently of the physical space in which they are situated. Our approach to this vision is to investigate a flexible wearable platform that supports dynamic composition of wearable devices, ad hoc connection to devices in the environment, continuous access to multimedia networks, as well as adaptation of content to devices and user context.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Iconographic Networks: Unveiling Exchanges and Connections between Illuminated Manuscripts in Late Medieval Italy (1260-1510)', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Brunetto Latini’s Tresor and Tesoretto, Francesco da Barberino’s Documenti d’Amore, Dante Alighieri’s Commedia, and Francesco Petrarca’s Trionfi are four closely interconnected literary works composed in, or strictly related to, Tuscany between the 13th and 14th centuries. These texts share a central focus on visual component, inspirational sources, and historical and material contexts. While these interconnections have received notable scholarly attention from a literary perspective, a comprehensive and detailed examination of their convergences in terms of material and illustrated traditions has never been conducted. To address this gap, IcoNet will systematically compare the full range of iconographic representations produced for each work, from their composition to their latest figurative transpositions in manuscript books (ca. 1260 to ca. 1510). IcoNet will operate on two complementary levels: (1) examining each manuscript tradition individually, focusing on internal iconographic links; and (2) analyzing each tradition in relation to every other one, particularly through common iconographic choices for shared subjects or figurative modules. The primary objective is to map and delineate the unexplored iconographic network that deeply connects these works. By introducing an innovative highly interdisciplinary methodology, that integrates traditional stylistic and geographical classification criteria with extensive analysis of iconographies and compositional modules, IcoNet aims to reconstruct one of the most significant and intricate networks of cultural exchanges spanning two centuries of Italian and European civilization. This foundational iconographic network case study, crucial for its role in the Italian vernacular literature, will establish a new, robust system
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Production of biogas and fertilisers out of wood and straw' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

The proposed project is based on a modular biogas reactor for cellulose-rich materials which provides energy from the use of biogas and fertilisers from the use of the digestate. Biomass can be considered as a strategic resource because not only is it renewable, but it is also available everywhere and can provide products of vital interest to sectors of strong external dependence (i.e. fuel for transportation, electricity, chemicals etc.), and also because it may raise benefits for the environment and for socio-economic development, (particularly in a rural areas). Retention of the rurallandscape Improved operation of biogas plants Use of lignin-containing materials (straw, wood, grass) 7 extension of input materials for anaerobic digestion Closed nutrient cycle by bringing the produced fertilisers back on the fields Less environmental impact by fertilisers Increased use of renewable materials 7 no net gain in carbon dioxide emissions and negligible S02 and N0x emissions compared to fossil fuels Creation of an alternative use for straw since buring of straw is banned in some European countries Reduce reliance upon finite fossil fuels Environmental sustainable production of energy Reduction of soil erosion as ploughing in straw is expensive and very energy intensive and does not always improve soil structure Reduced capital and operation costs Strengthening of farmers 7 sale of products (e.g.fertilisers) can generate an extra income Competitiveness of agricultural sector especially in the accessing countries Creation of employment possibilities especially in rural areas
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Generation of Position Specific organoids to study human neuromuscular system development and disease' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Locomotion results from the interaction between muscles and the nervous system. Dysfunction of such cells results in deadly diseases such as spinal muscular atrophy (SMA) and amyotrophic lateral sclerosis (ALS). These diseases often show regional selectivity but the underlying reasons remain obscure due to the lack of a suitable model system.  In previous work of my laboratory, we established a 3D neuromuscular organoid (NMO) model that allows the simultaneous generation of spinal cord neurons and skeletal muscle cells from human pluripotent stem cells (hPSCs) through a bipotent neuromesodermal progenitor (NMP). NMPs, located in the posterior part of the embryo, are driving axial elongation and coordinated growth of the trunk neuromuscular system. We coaxed hPSC derived NMPs to develop into neuromuscular organoids that form functional neuromuscular junctions supported by the presence of terminal Schwann cells and central pattern generator-like circuits. Thus, we are in the unique position to study in an organoid model the regulatory mechanisms involved in the formation and maintenance of the human neuromuscular system, and the disruption of these mechanisms in diseases. We will (i) identify the molecular requirements for the Generation of Position Specific (GPS) organoids representing distinct spinal cord segments, (ii) use NMOs to model and study ALS and SMA including the establishment of a drug screening platform and (iii) assemble hPSC-derived cerebral organoids and NMOs to include in the model human corticospinal tracts. In the long term, the information gained will have important implications for understanding and eventually treating neuromuscular diseases.


**Keywords:** Neuromuscular Organoids, NMOs, Neuromuscular System Development, HOX genes, Neuromuscular Dis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'European Birds of Passage - An Empirical Legal Theory of Temporary Labour Migration in Europe' (E-BoP) targeting Horizon Europe.

assistant: **Abstract**

The E-BoP project is an innovative study of the legal framework for temporary labour migration in the European Union (EU).  While unevenly researched, the subject is hotly debated and in continuous expansion. Temporary labour migration increasingly represents the compromise between calls to ""take back control"" of borders, and the demands from employers of access to migrant workforce. The legal regulation of this phenomenon is grounded on concepts, such as ""temporariness"" and ""labour market"", which are either not defined by the law or in conflict with their socio-economic reality. E-BoP explores these concepts through an empirical legal analysis to address the foundations of the legal framework for temporary labour migration in the EU. In doing so, it covers forms of temporary labour migration which legal doctrine has never analysed together, namely posting of workers, seasonal work, and intra-corporate transfers. The project aims to answer a set of questions concerning this legal framework:  what is the implicit definition of ""labour market"" accepted by legislation and courts, and what are its boundaries? What does the law mean when it classifies certain migrant workers as ""temporary""? What would be the legal and socio-economic consequences of conceiving temporary labour migrants as fully integrated in the Member State where they perform their work? The E-BoP project triangulates the results of a systematic analysis of legal documents with quantitative analysis of the phenomena at stake to explore the real world meaning of concepts upon which the legal regulation of temporary labour migration in the EU is construed. As such, the ambition of E-BoP extends beyond the field of labour and social rights, and into other legal disciplines and branches of social scien
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Integration of Capacitor, Thermoelectric and PhotoVoltaic thin films for efficient energy conversion and storage' in the context of a Horizon 2020 call.

assistant: **Objectives**

The possibility of having a unique device that converts thermal and photonics energy into electrical energy and simultaneously stores it, is something dreamed by the PI since the beginning of her research career. To achieve that goal, this project aims to gather, in a single substrate, solar cells with up-conversion nanoparticles, thermoelectrics and graphene super-capacitor, all made of thin films. These three main components will be developed separately and integrated sequentially. The innovation proposed is not limited to the integration of components, but rely in ground-breaking concepts: 1) thermoelectric elements based on thin film (TE-TF) oxides; 2) plasmonic nanoparticles for up conversion of near infrared radiation to visible emission in solar cells; 3) graphene super-capacitors; 4) integration and optimization of all components in a single CapTherPV device. This ambitious project will bring new insights at large area, low cost and flexible energy harvesting and comes from an old idea of combining energy conversion and storage that has been pursued by the PI. She started her career in amorphous silicon thin film solar cells, later she started the development of thin film batteries and more recently started a research line in thermoelectric films. If approved, this project will give financial support to consolidate the research being carried out and will give independence to the PI in terms of resources and creative think. More importantly, will facilitate the concretization of the dream that has been pursued with hard work.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Post-glacial recolonisation and Holocene anthropization impact on populations of shrews and hedgehogs from Western Europe inferred from zooarchaeology, historical biogeography and ecological modeling'.

assistant: **Innovation**

At the end of last glaciation, ca. 15 000 cal. yrs ago, small mammals which had receded in the glacial refuges of southern Europe during the last pleniglacial started to spread again northward. This movement, which lasted several millenia -and which is still operating in a few cases- has been investigated through a number of phylogeographic works relying chiefly on molecular grounds so far. Comparatively few has been done on the basis of actual zooarchaeological data, especially for insectivores, often neglected in palaeoenvironmental and palaeoclimatic reconstructions. Moreover, phylogeographical hypotheses derived from molecular data are strongly limited by human perturbations (e.g. anthropisation of the landscape, introduction of alien species, isolation of ecosystems) which have remodelled the phylogenetic patterns of many European taxa since the appearance of agriculture ca 7500 yrs ago. What we intend to do here is to reconstruct the process of post-glacial recolonisation in several species of shrews and of the European hedgehog in Western Europe on the basis of geo-referenced and well dated occurences. For this we will rely on 1) the I2AF databases, hosted at the MNHN and which holds several thousands of bioarchaeological records,  2) data derived from the literature, 3) the production of new data by the identification of insectivores in key series in Spain, France, Belgium, Ireland and Britain. These data will be modelled using ecological niche modelling and integrating data on climate, vegetal environment and coastlines, which significantly evolved during this period. Thus, we hope to produce a dynamic model contributing 1) to understand how small mammal communites have formed at the beginning of the Holocene, and 2) to reconstruct how was the distribution of i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Multi-scale biomechanical modelling and simulation of the intervertebral disc' (DiscSim).

assistant: **Concept**

Computational mechanics techniques have revolutionised the design and analysis of engineered structures. The emerging field of Computational Biomechanics (CB) applies these techniques to study biological structures and systems. A key advantage of CB is the ability to predict physical quantities (such as flow and deformation) over a range of length and timescales in biological tissues, whereas such quantities are difficult or impossible to measure experimentally in living organisms.This project will develop multiscale CB approaches to analyse the largest avascular structure in the human body, the intervertebral disc. The intervertebral disc is subjected to large deformations during spinal motion, withstands transient loads of up to 9 times body weight during rigorous physical activity, and due to its lack of blood supply, its nutrient supply is provided by fluid-borne diffusion through the disc tissues from the adjacent vertebral bodies. A multiscale model of the intervertebral disc will substantially advance the study of disc mechanics by linking whole disc loading and deformation to the mechanical microenvironment experienced by cells embedded within the disc tissue. This approach promises new insights into tissue repair and remodelling in healthy discs, into tissue damage and cell death in degenerate discs, and in predicting disc response to emerging treatments such as annular repair and nucleus replacement.