RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Perception in Action: Neural Dynamics of Sensorimotor Interactions in Touch' (SELF-TOUCH) targeting Horizon Europe.

assistant: **Abstract**

Self-touch is perceived as less intense than physically identical touch from an external source. Current computational theories propose that the brain predicts and dampens the sensory consequences of actions, a phenomenon referred to as sensory attenuation. When prediction mechanisms fail, it can have powerful consequences for perception, from mild perceptual disturbances to more extreme hallucinations and delusions that are characteristic of psychosis-spectrum disorders such as schizophrenia. Predicting touch is likely supported by specific patterns of brain oscillations, subserving brain connectivity, yet little is known about these mechanisms. SELF-TOUCH will use cutting-edge methods from magnetoencephalography to study oscillatory dynamics during the prediction, generation and attenuation of self-touch. The objectives are to i) reveal how the brain dynamically predicts touch during the time-course of actions, ii) to study how the brain treats violations of sensory predictions and iii) to examine these predictive mechanisms in individuals with high schizotypy. Understanding the temporal dynamics of sensory prediction could reveal how perceptual disturbances manifest in psychosis and may aid development of biomarkers for early intervention of schizophrenia. The project will result in a synergy between the applicant’s highly interdisciplinary profile and the high quality of the host institution. It will be completed at a world-leading research-led institution (Karolinska Institutet, Department of Neuroscience) within a team led by Dr. Konstantina Kilteni providing theoretical knowledge and practical expertise in sensorimotor neuroscience and sensory attenuation. The applicant brings highly complementary expertise in cognitive neuroscience, psychophysics, and neural tim
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Sugar Mimetics: Multicomponent Inhibitors of Glycosyltransferases' (GLYCOMIGS) targeting Sixth Framework.

assistant: **Abstract**

The Inhibition of Glycosyltransferases as a Potential Therapeutic Target: It has been estimated that 2-3% of mammalian genomes are associated with the production of carbohydrate-processing proteins and enzymes. Of these by far the most widespread class of such proteins are glycosyltransferases (GlyTs). This remarkable but poorly understood class of enzymes are ubiquitous in nature and play a wide range of fundamental biological roles in events as diverse as fertilization, cancer, immunology, cell signalling and protein folding. Importantly, certain types that perform highly specific functions associated with disease states have been identified and offer themselves as potential targets for inhibition. Yet, to date few potent and specific inhibitors of any of the many thousand of potential enzyme targets have been identified. None are in development as drugs. We aim to develop and apply recent chemical discoveries in our laboratory for the construction of sugar mimetics to the creation of a new generation of mu lticomponent inhibitors of GlyTs. By using such a component assembly approach, we will design and optimize mimetic modules that will fit key binding pockets of these enzymes. In this way we will not only develop an improved understanding of this class of e nzymes but will also use this understanding to create potent inhibitors. As directly relevant GlyTs of high potential therapeutic utility, we have chosen to target Mycobacterial GlyTs as model systems in which to explore this novel but general modular meth odology that we believe will allow ready adaptation to other, important GlyT targets, such as e.g., fucosyltransferases. If successful this programme would therefore not only create leads of potential utility in the treatment of tuberculosis but methodolo gy ap
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Linear and cyclic double-strand molecular wires' (Two-Strand).

assistant: **Innovation**

This project will focus on double-strand nanowires and nanorings consisting of butadiyne-linked porphyrin oligomers. One objective is to create double-strand linear conjugated polymers with useful nonlinear optical properties for ultrafast all-optical communication systems. Another objective is to explore a new approach to template-directed synthesis, whereby one nanoring acts as a template to direct the construction of a second complementary nanoring. Double-strand porphyrin nanorings are of high interest because of their resemblance to photosynthetic light-harvesting complexes. They are also expected to have interesting nonlinear optical properties.Professor Anderson is a leading expert in supramolecular chemistry and the engineering of molecular wires. The Department of Chemistry at Oxford is one of the top chemistry departments in Europe with outstanding research facilities.Christiane Knappke recently completed her PhD at the University of Cologne in the field of N-heterocyclic carbene chemistry. During her PhD work, she synthesised some remarkable electron-rich pi-systems. This experience made her eager to learn about the synthesis and characterisation of larger functional pi-systems. Anderson’s group provides an ideal environment for gaining this expertise. This project will provide her with high-level hands-on training in supramolecular chemistry, template-directed synthesis, electrochemistry, photophysical techniques and EPR spectroscopy. She has the necessary expertise to make fast progress with the project, and to rapidly acquire new skills. This fellowship will put her in a very strong position to start an independent research career.The project includes collaborations with physical chemists, physcicists and materials scientists, located in Oxford and other E
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Reconstruction and generic automorphisms' in the context of a Sixth Framework call.

assistant: **Objectives**

The project is on the borderline between model theory (mathematical logic) and permutation group theory (algebra), though ideas from other fields such as set theory and combinatorics are involved. The goal is to investigate the following question for a range of first order structures: if one knows the automorphism group Aut(M) of a countable first order structure M, how much is known about M?The question only makes sense in highly symmetric contexts, such as for omega-categorical structures. Work on reconstruction so far has mainly centred on the small index property, which enables one to recover the topology on Aut(M) from the pure group, and hence to recover M up to bi-interpretability. The proposal is partly to obtain reconstruction results for new classes of structures, by developing new methods for cases where current techniques fail; and partly to prove positive results on a new kind of reconstruction, namely interpretability of a structure in its automorphism group.The main candidates for investigation are a class of combinatorial constructions due to Hrushovski, which are crucial in model-theoretic simplicity theory, and the class of smoothly approximable structures. The latter have a natural algebraic characterization in terms of covers of classical geometries. The intended methods stem from an approach to reconstruction developed by M. Rubin, which has been neglected in the published literature so far. The proposed approach will involve the notion of generic automorphism, which is highly relevant t o reconstruction and has also independent interest. Applications to reconstruction questions in the non omega-categorical case are envisaged.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Development of a robotic maintenance system for wind turbine blades'.

assistant: **Objectives**

The wind energy sector continues growing rapidly even under the pandemic, as an estimated 93GW wind capacity was installed in 2020 globally. After installation, wind turbines are expected to run around 20-25years, during which O&M (operation and maintenance) becomes crucial in maximising the economic and environmental benefits of wind assets. This project aims to develop a complete solution for robotic based inspection and repair of wind turbine blades (WTBs), both onshore and offshore. Firstly, we will integrate thermography and shearography with laser heating, so that advanced lock-in techniques will be achieved for in-situ inspection of both surface and subsurface defects within WTBs. (Current techniques including drone-based are limited to surface defects only). Secondly, a compact and efficient robotic deployment system will be developed which will hold the inspection unit and a robotic repair arm. The robotic system will be operated by engineers working on ground (for onshore wind farms) or on a vessel (for offshore wind farms). When defects are detected and deemed reparable, the repair arm of the whole system will be activated to rapidly repair the faulty area of composite components by resistance welding for joining and/or disassembly. Comparing to the traditional adhesively bonding for repair, the proposed resistance welding with optimised processing would significantly reduce the curing cycles/time with much fewer preparation for surface treatment steps while it will be more easily designed to integrate with robotic arm. The whole system will be operated remotely by engineers working on ground or on a vessel without risking their lives working in the sky on WTBs. Field trials on wind towers will be conducted to validate the system.


**Keywords:** Wind turbine
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'PELVIc Floor Evaluation live TRACKing – Real-time prediction of perineal trauma' to be submitted under Horizon Europe.

assistant: **Abstract**

Pelvic tissues, supporting the pelvic floor, can change in physical properties during lifetime, leading to dysfunctions commonly known as Pelvic Floor Disorders (PFDs). These disorders, encompassing pelvic pain, pelvic organ prolapses, urinary or anal incontinence or dyspareunia, affect 32% females and 16% males worldwide, making it a major health concern. Various factors such as older age, menopause, obesity or intense physical activity are significant contributors. However, the occurrence of PFDs is mainly due to traumatic events. Indeed, perineal tears, taking place in 90% of vaginal deliveries (VDs), have been identified to be a high-risk factor of PFDs. As an answer, PELVITRACK’s ambition is to enable the systematic prevention of PFDs, ensuring earlier diagnosis, more reliable prognosis, and more efficient care. More specifically, the project will design a real-time turnkey lab-scale solution to monitor perineal tearing during VD and minimize pelvic traumas. This revolution in the monitoring of the pelvic floor will be achieved through a hybrid experimental and numerical approach, leveraging ex vivo data and computational modelling on pig perineum to select IDEVs (Investigated DEVices) that will be adapted and validated in vivo on animals (preclinical study) and women (clinical studies). To achieve its ambitious goal, PELVITRACK gathers a unique interdisciplinary consortium of 11 partners including renowned research institutions, universities, hospitals and SMEs to cover all the required scientific expertise and knowledge in mechanics, computer science, electrical and thermal engineering, acoustics, optics and obstetric physics. Exploring new technologies to predict perineal trauma in real time, PELVITRACK delineates a high-risk/high-gain proposal that will signifi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Computational model predictive and adaptive control tools' to be submitted under Horizon Europe.

assistant: **Abstract**

Model predictive control (MPC) is applied with success in industry for automating constrained multivariable dynamical systems in an optimized way. However, some crucial aspects of MPC design largely remain to be addressed to unleash the full potential of MPC in applications: the efforts required to collect experimental data, identify the prediction model, and calibrate the controller, must be reduced considerably; the controller must self-adapt seamlessly to cope with unforeseen changes and not require excessively demanding computer hardware for deployment. This project aims to address methodologically such aspects and establish a theoretical and algorithmic framework for designing the next generation of nonlinear adaptive embedded MPC systems from data. Firstly, to reduce data-collection efforts significantly, we will develop tools that enable the design of experiments based on novel active-learning approaches to nonlinear system identification, coupled with robust MPC schemes to ensure safe data collection. Secondly, to cut calibration efforts down drastically, we will devise innovative preference-based methods that can learn from calibrators' assessments and automatically detect critical closed-loop scenarios. Thirdly, we will develop methods for seemingly adapting the prediction model at runtime to cope with uncertainties and model mismatches not seen during the design, as well as methods for approximating the control law with different tradeoffs between the amount of required online computations and the obtained closed-loop performance. To demonstrate the potential industrial use of the methodologies and algorithms developed in the project, we will formulate and solve laboratory benchmark problems on an experimental robotic platform, a challenging system for data-d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Sustainable Micronutrient Interventions to Control Deficiencies and Improve Nutritional Status and General Health in Asia'.

assistant: **Innovation**

Interventions to improve nutritional status are of critical importance to achieve Millennium Development Goals (MDGs). Micronutrient deficiencies, mainly iron, zinc, vitamin A and iodine deficiencies affect billions of people worldwide, are responsible for more than one  million child deaths per year and prevent a third of the world’s children from reaching their intellectual and physical potential. The SMILING project ""Sustainable Micronutrient Interventions to controL deficiencies and Improved Nutritional status and General health in Asia"" will produce a new, feasible and sustainable nutrition intervention agenda, which will be country-specific and directed to women of reproductive age (non-pregnant women, pregnant and lactating women) and young children under 2 years of age. The project focuses specifically on the South-East Asian region because of the diversity in the extent and severity of malnutrition in that region and on the diversity of political, economic, social and cultural contexts. The SMILING proposal deliberately avoids expressing pre-conceived views on which interventions should be prioritized currently or in the future as the deliverables of the Action will reflect the views and opinions of a wide range of stakeholders in the region who will be consulted during the project.The ultimate objective of the Action is to integrate priorities for appropriate, efficient, feasible and sustainable interventions to improve micronutrient status, health and development of women of reproductive age and young children primarily into the national policies of the five target countries in SE Asia and in the agenda of the civil society, private sector, international organizations and NGOs. The goal is not only protecting people from hunger but also to guaranty food and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Demonstrating innovative pathways addressing water and soil pollution in the Mediterranean Agro-Hydro-System'.

assistant: **Objectives**

Path4Med is a multi-participatory and multidisciplinary project that will pave clear pathways towards zero water and soil pollution in the agro-hydro-system of the Mediterranean sea basin and other European seas through an innovative triple bottom line approach achieving economic, social, and environmental sustainability to ensure human well-being and ecosystems functioning. Path4Med will advance and consolidate agricultural management technologies and solutions within an inclusive and open participatory environment, it will evolve and mainstream novel monitoring technologies and integrated solutions, it will assess the technical feasibility and socioeconomic viability of cascades of solutions through an integrated modelling framework, it will quantify the effectiveness and the net impact of these solutions, and ultimately it will empower Citizens to take action against pollution of soils, waters and the ocean, through clear measurable evidences, increased awareness, and water literacy. Path4Med pathways will be applied and demonstrated in large scale, integrated, Demonstration Sites established in representative Mediterranean areas, in areas representing other European seas and in associated regions. A digital platform and other relevant digital tools will be established to facilitate Path4Med actions, information and knowhow communication, and to support data exchange and data feeding to international Observatories and Knowledge Systems.


**Keywords:** soil and water pollution, excess nutrients, monitoring technologies, Earth Observation, Biobased indicators, agricultural management technologies, Common Agricultural Policy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Astaxanthin Metabolism in Salmon: A Cutting-Edge Multi-Omics Exploration'.

assistant: **Objectives**

Astaxanthin (Ax) is crucial for achieving the pink-red hue in farmed Atlantic salmon, a key quality factor at sale. Since salmon cannot produce Ax naturally, it is added to their feed. Beyond pigmentation, Ax's antioxidant properties may boost salmon growth and health. However, farming challenges have led to a decline in muscle Ax levels, possibly due to rapid growth, welfare challenges, and low retention rates. Despite Ax's high cost and its importance in fish feed, retention in salmon remains low, under 12%. Improving Ax retention and pigmentation is a key challenge in salmon aquaculture, essential for the industry’s growth and salmon health. The SAXOmics project aims to enhance understanding of Ax metabolism, focusing on its absorption, transport, and retention, to improve Ax retention, feed and fish quality, and address pigmentation challenges. Enhancing Ax absorption and retention is crucial, as dietary lipids and other factors promote Ax retention, though the exact molecular mechanisms are not fully understood. Recent research suggests that gut microbiota affect lipid metabolism, pointing to a possible role in the Ax mechanism. By employing a groundbreaking interdisciplinary approach that integrates multi-omics technologies and advanced bioinformatics tools, this project will delve into the molecular mechanisms of Ax metabolism and develop innovative feed formulations to optimize Ax absorption, transport, and retention. The project will include enterocyte and muscle cell culture and salmon pigmentation trials, complemented by thorough training in omics technology, animal ethics, experimental design, and scientific communication. Joint efforts with  Nord University, NTNU, and BioMar will support practical applications and commercialization of the findings. By month