RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'IFMIF-DONES Preparatory Phase' in the context of a Horizon 2020 call.

assistant: **Objectives**

The International Fusion Materials Irradiation Facility - Demo Oriented NEutron Source (IFMIF-DONES) is a novel Research Infrastructure based on a unique neutron source with energy spectrum and flux tuned to those expected for the first wall in future fusion reactors, to investigate radiation damage phenomena and to characterize materials irradiated under such conditions. It will also develop a unique high-current high duty-cycle accelerator technology, liquid metal target technology and advanced control systems.Since 2007, the original IFMIF project has been pursued by Japan and the European Union under the Broader Approach Agreement in the field of fusion energy research and in December 2017 Fusion for Energy (F4E)positively evaluated the Spain-Croatia joint proposal to site DONES in Granada (Spain) and at this moment a wide international collaboration is being fostered to design and build the facility.The primary goal of the IFMIF-DONES Preparatory Phase project is to elaborate and draft the consortium agreement allowing for the construction of the facility.During the Preparatory Phase, the Project will deal with the financial, legal and organisational issues related to the international character of the facility during its construction and operation phases. The Preparatory Phase is also the ideal framework to attract other partners, also to ensure the operation and exploitation of the project, such as the already confirmed Andalucía Region Authority and the Spanish Government, EUROfusion and F4E that cover about 75 % of construction costs.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Collectivism in the Digital Era: Novel Approaches to Worker Mobilization and Interest Representation' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Throughout Europe, trade unionism is in decline. Membership levels have fallen, the coverage of collective bargaining has contracted, and union influence has decreased in the workplace, the labour market, and the corridors of political power. While the consequences for individuals and societies are contested, a wealth of evidence suggests that this has contributed to a widening of the gap between the wealthiest and the poorest in our societies. Wealth inequalities and economic insecurity have been linked, meanwhile, to resurgent nationalism and the growing popularity of extremist political parties in several European states and elsewhere.  In the last few years, there have been intriguing signs of the beginnings of revitalisation: of new forms of trade unionism and or worker claim articulation, representation and mobilisation, that harness social media and other forms of digital technology to reach and communicate with workers, including young workers. Conscious of the high stakes involved CODE investigates examples in the UK, Spain and Greece. Constructing case studies, it seeks to establish what kinds of worker mobilisation and collective action have been and are likely to be successful in the current digital era. Through contextual analysis and comparison, it aims to identify how interest representation and workers’ empowerment might be enhanced. In particular, it considers what role law and other institutions, both public and private, might play in enabling this process. Which innovative legal solutions can be designed to assist mobilization and interest representation in the digital era? In pursuing these objectives, CODE advances beyond the state of the art by employing and further developing a cutting-edge interdisciplinary approach to the study of labour markets
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'New Anionic Ligands for Base Metal Catalysis' (SilaCoFeCC), addressing dissemination and exploitation.

assistant: **Impact**

The development of catalysts based on cheap and non-toxic first-row transition metals in replacement of the traditional precious metals is broadly recognized as a key challenge for the development of environmentally friendly chemistry. Here, we propose the development of novel silicon-based ligands specifically tailored to support organometallic chemistry at first-row transition metals (Fe and Co) and their application to the mechanistic study and development of C-C bond forming reactions. The applicant has received his undergraduate (EPFL) and graduate (ETHZ) education in Switzerland and then spent 2.5 years as a researcher at the California Institute of Technology (Caltech); he is now returning to Europe to start building up an independent research and teaching career at Utrecht University. The knowledge obtained in this research project will be shared with young European scientists through teaching and mentoring.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The study of prion propagation, pathogenesis and intermammalian species barriers in transgenic and other models of prion disease' (1994-1998) under Fourth Framework.

assistant: **Objectives**

(1) To further our understanding of the fundamental biology of prion propagation, and of the mechanisms and pathways leading to late onset neurodegeneration.(2) To study possible therapeutic strategies for the human prion diseases. (3) To estimate the efficacy of the species barriers limiting transmission of BSE and scrapie to humans to address the risk to public health within the EU posed by BSE and other animal prion diseases. (4) to establish the full phenotypic range and transmission characteristics of the human prion diseases.Prion diseases are transmissible neurodegenerative diseases of humans and animals. They have become an intense area of biomedical research activity for two reasons: Firstly, the transmissible agent or prion appears to be devoid of nucleic acid and consists essentially of a modified form of a host derived protein. Secondly, the epidemic of an apparently new animal prion disease, BSE, in the UK has raised legitimate public concerns of a risk to human health from eating infected tissues. Such concerns have had a major impact on the UK agricultural industry, and cases of BSE are now being reported throughout the EU. In addition, there have been concerns over the safety of pharmaceutical products derived from human or bovine tissues. We will develop and evaluate transgenic mouse, cell culture and in vitro models which, as well as allowing an experimental estimation of the risks of transmission of BSE to humans and a complete assessment of the transmission characteristics and phenotypic range of the human prion diseases, should provide the tools to study the mechanisms and pathways of prion neurodegeneration. These models will be used to evaluate therapeutic strategies and for testing of novel therapeutics. This application links with both current E
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Formate-dependent Regulation of Cancer Metastasis' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Mechanisms underlying cancer metastasis are poorly understood and context dependent. An essential feature of disseminating cancer cells is metabolic plasticity which allows cellular adaptation to changing environmental conditions along the metastatic cascade. I discovered in 2016 the phenomenon of formate overflow, an alternative pathway for serine catabolism via folate-mediated one-carbon (1C) cycle. Instead of using formate for nucleotide synthesis (to support proliferation), formate overflow is characterised by formate excretion from cancer cells. Furthermore, I have convincingly demonstrated that mitochondrial 1C metabolism and increased extracellular formate concentrations promote cancer metastasis in a growth-independent manner. However, it remains unknown which intermediates of 1C metabolism contribute to this phenotype, how formate controls metastasis and how it can be targeted therapeutically.  To cross the current edge of knowledge, I will (1) take advantage of genetic and newly developed analytical methods to dissect how the formate-dependent effects are propagated in cells; (2) describe intrinsic mechanisms to explain how the formate signal is relayed to promote metastasis and (3) exploit formate overflow for cancer cell killing by directly targeting the formate molecule. 4M8 will explain a novel concept of how a mitochondrial metabolic signal drives cancer cells towards a pro-metastatic phenotype and how this knowledge can be translated into a signature to analyse the metabolic state in human tumour samples. Finally, we will develop a novel tool to target formate directly within cancer cells. In sum, our research will shed light on an unexplored field of cancer metabolism providing the foundation to develop novel treatment approaches against metastatic canc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Characterisation, utilisation and maintenance of biological diversity for the diversification and sustainability of catfish culture in South-East Asia' in the context of a Fourth Framework call.

assistant: **Objectives**

The main objectives are as follows:* To characterise species, populations and strains of autochtonous Clariidae and Pangasiidae catfish.* To contribute to the knowledge of their life history.* To implement monitoring tools that could be used subsequently for the characterisation and monitoring of genetic diversity in cultivated fish stocks (ie. development of DNA microsatellite loci).* To assess and compare the aquaculture potential of species, populations and hybrids in the Pangasiidae and Clariidae.* To develop artificial propagation techniques adapted to local conditions in pangasiid species for which captive broodstocks are available.Expected OutcomeThe work carried out in this project should provide new basic information on the biodiversity and zootechnology of the clariids and pangasiids in the SE Asian region. The precise description and characterisation of species, populations and strains represents an important precondition to the sustainable management of their cultivated and natural stocks and to guide conservation efforts of these economically important resources. It will also contribute to a better knowledge of their phylogenetic and zoogeographic relationships. The evaluation of the aquaculture potential of the autochtonous species (diversification) and the optimisation of their rearing cycle (particularly artificial propagation) through technologies adapted to the local conditions are essential elements for a better production in the future.The key activities envisaged are:* Identification and characterisation of species, populations and strains using three complementary disciplines and methods: morphometry, genetics and parasitology (specific Monogenea). The genetic studies will include different techniques adapted to the research goals: Protein electrop
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Precision measurements in molecules with frequency combs', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Precise frequency measurements enable accurate determinations of physical constants, stringent tests of fundamental theories and searches for possible drifts of the fundamental constants. Simple atoms, hydrogen in particular, have long been the dedicated systems for confronting experimental data and accurate quantum electrodynamics theoretical calculations. With continued progress to ab initio calculations, precision measurements in small molecules, such as molecular hydrogen H2, are gaining much relevance and may be envisioned as an independent way to determine fundamental constants and to test quantum-chemistry theory.  In this project, we will develop an instrument of precision molecular spectroscopy, based on frequency combs, broad spectra composed of equidistant narrow lines whose absolute frequency can be known within the accuracy of an atomic clock. Building on our unique know-how, this revolutionary ultraviolet spectrometer will simultaneously combine broad spectral coverage, Doppler-free resolution and extreme accuracy for precise studies of small molecules. Using two-photon excitation and dual-comb spectroscopy with comb lasers of low repetition frequency, we will devise an optical analogue of the Ramsey-fringe method where many molecular transitions will be simultaneously and unambiguously observed and assigned.  While such a spectrometer will enable significant progress in our understanding of the structure of many small molecules, it will first be applied to absolute-frequency measurements of rovibronic transitions in the EF – X  system of H2 around 3000 THz. The measured frequencies can be used to benchmark molecular theory in the involved ground and excited states. They may contribute to an improved determination of the dissociation energy of H2, set new
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Condition monitoring system with controlled repair capabilities for process automation purposes in repair welding services' to be submitted under Fourth Framework.

assistant: **Abstract**

The European industry has to consider an annual lost of several billion of ECU due to wear and corrosion with tremendous economical and environmental impact. Although, many parts affected by wear during operation are worth to be recovered, adequate repair services are often questionable due to economical reasons caused by technical and technological deficits. In order to promote the repair welding business. its competitiveness on the international market, and to overcome existing technical and technological problems, the proposed project intends to improve productivity, working conditions, cost-effectiveness, and product quality as well as life times of the repaired parts by introduction of advanced technologies for process control and automation into the field of repair welding. Focusing in particular to the improvement of controlled repair capabilities combined with mechanised or robotised repair welding, the key research activities will address: the sensor-driven identification of wear conditions with integrated knowledge-based repair planning capabilities the integration of monitoring and online-process control capabilities with special regard to relevant process conditions, quality of the welds, and life-time extension of the recovered parts the introduction of repair welding automation to increase productivity and to guarantee reproducable process conditions, and the design and realisation of a prototype demo platform for practical tests and to provide practical repair options to commercial application. Besides economical benefits directed to the repair service itself, the overall industrial and environmental benefits for the European industry derived from the project results are obvious in terms of reduced repair costs, improved repair quality, extended life cycl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'MOFs as Catalysts and Adsorbents: Discovery and Engineering of Materials for Industrial Applications' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

A major challenge facing European industry involves the development of more specific, energy saving processes with less environmental impact. The recent development of Metal Organic Frameworks (MOFs) may prove a major milestone in achieving these goals. MACADEMIA project is an extension to an FP6 STREP (DeSANNS) which highlighted some MOF materials for CO2 capture and storage. It will expand and continue this work on a much larger scale.                                           The three Total branches will focus on bringing MOFs to key market sectors - gas separation and storage, liquid separation and catalysis. The Total-led consortium, with 11 academic partners from across EU, one leading South Korean partner, among world leaders among their particular domain of MOF science, will be contributing to the project, with a dedicated management partner. MACADEMIA intends to produce new MOFs and optimise those already of promising interest, characterise MOFs using specialised techniques, test MOFs using a three-tiered process, use predictive modelling and demonstrate the use of MOFs in key industrial processes. It will target separation processes in gas / vapour phase (propene/propane, acid gases separation, CO2 and H2 purification), in liquid phase (xylene separations, recovery of N- and/or S-compounds from hydrocarbons), and in catalysis (Lewis-acid MOFs as catalysts for epoxide polymerization, redox-active MOFs as catalysts for hydrocarbon autoxidation). Several of MACADEMIA’s targets are expected to reach pilot scale whereas a blue sky approach will be taken for others giving room for innovation and step change. An attractive project, it is open to young researchers with industrially coordinated research to counterbalance competition from USA and Japan and able to cont
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'European railways optimisation planning environment - transportation railways integrated planning' under Fourth Framework.

assistant: **Concept**

The EUROPE-TRIP (briefly TRIP - Transportation Railways Integrated Planning) is part of a wider initiative referred to as EUROPE (European Railway Optimisation Planning Environment) which is supported within the EU RDT Programme.TRIP addresses the higher part of the rail planning process and aims to assist the management of infrastructure by providing a comprehensive model to represent the short and medium/long term planning of the railway system, taking into account the evolution of the European market and transport policies.TRIP implements the specific transportation facets of the EUROPE programme, in order to:a. define a business planning model of the rail system, focused on the management of infrastructure;b. analyse the market structure and find mechanisms how the infrastructure must co-ordinate with the transport companies in providing access-to-track;c. determine the cost of using the infrastructure;d. evaluate the methods for assessing the capacity of rail lines, with particular reference to European corridors.The project follows an experimental approach so as to engineer the Directive principles and incorporate a marketgame approach to simulate the behaviour of market operators, via management science and game theory algorithms.It provides the basis to determine a standard cost model for the EU Railways, in order to address track pricing and other investment policies. In addition it will use simulation as a leading tool in assessing the rail lines capacity, taking a European corridor as case study (i.e. Italy-France-UK). Finally the project aims to develop a prototype software model in order to demonstrate the research concepts and provide a tool to better disseminate its final results. %