RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Therapeutic TriMix / mRNA based Vaccine in Chronic HIV-1 Infected Patients Receiving Antiretroviral Therapy', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

To find a therapy alternative to cART for life is one of the hot topics of investigation in HIV field. Therapeutic vaccination seems to be the best option. We have reported in a double-blind placebo controlled study some of the best, most solid data showing that HIV-1 specific immune responses elicited by therapeutic dendritic cell (DC) vaccines pulsed ex vivo with inactivated autologous whole virus could significantly change pVL set-point (mean peak drop of -1.2 log10 copies/ml). Similar efficacy has been found in a preliminary non controlled clinical trial using DC electroporated with mRNA encoding autologous HIV-1 antigens. However, the logistics of developing a specific vaccine by ex vivo manipulating autologous DC for each patient may be prohibitive. Therefore, we propose that in vivo targeting of DC by direct administration of a rational designed HIV mRNA encoding immunomodulating proteins might be an attractive alternative to target DCs in situ. Our candidate is highly innovative: 1. It is a mRNA based immunogen: it is expected to have a good safety profile, it is classified as nongene therapy by the American and German authorities, is easier to produce and to store regardless of the encoded antigen and is not restricted to a defined HLA type of individuals. 2. The HIV antigen encoded by mRNA has been selected with a rational design: based on our previous works selecting viral targets of protective HIV-1 specific T cell responses in 3 large cohorts of HIV infected individuals. 3. The candidate includes TriMix to target DC in vivo: our data suggest that mRNA encoding a mixture of antigen presenting cells activation molecules (CD40L, a constitutive active variant of TLR4 and CD70) significantly enhanced the induction of antigen-specific T cells. If this candidate w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Biology-Inspired techniques for Self-Organization in dynamic Networks' (BISON).

assistant: **Concept**

BISON will explore the use of ideas derived from complex adaptive systems (CAS) to enable the construction of robust and self-organizing information systems for deployment in highly dynamic network environments. BISON will cast solutions to important problems arising in Ad-Hoc and Virtual networks, P2P and Grid computing systems as desirable global properties that systems should exhibit. We will then search for CAS, which can bring about these global properties. Yet BISON will seek to go even further by working to systematize this process to develop a coherent set of heuristics that can guide the search for CAS giving a desired global behaviour. Progress in this direction will give us a systematic framework for constructing solutions to the original problem that inherit the attributes of CAS, including self-repair and self-organization. We expect to achieve this goal by restricting the class of problems and by drawing inspiration from natural systems like insect colonies and immune networks.DESCRIPTION OF WORKThe complexity of modern Network Information Systems (NIS) has reached a level that puts them beyond our ability to deploy, manage and keep functioning correctly through traditional techniques. Part of the problem is due to the sheer size that these systems may reach with millions of users and millions of interconnected devices. The other aspect of the problem is due to the extremely complex interactions that may result among components even when their numbers are modest. Our current understanding of these systems is such that minor perturbations in some remote corner of the system will often have unforeseen, and at times catastrophic, global repercussions. In addition to being fragile, many situations arising from the highly dynamic environment in which they are d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Evidence-based treatment in mental health: optimised use of databases' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

Mental health problems are common and costly. Treatment is often not based on existing scientific evidence on effectiveness. The aim of this proposal is to widely disseminate trial-derived evidence of mental health treatment, thereby improving rationality of treatment decisions and quality of life for the psychiatric patients and their families. This goal will be achieved by pooling existing European registers of published and unpublished trial evidence to create a unique, multi-lingual, evidence-based, widely disseminated electronic database. In addition, existing evidence will be actively disseminated by compiling a comprehensive electronic EU-PSI Mental Health Library, summing up available systematic reviews, mental health treatment assessments, and evidence-based guidelines.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Multimedia technology main-interest users network' (MEDIANET) targeting Fourth Framework.

assistant: **Abstract**

Standards in multimedia technology are not available in a world-wide accepted form. Existing standards of methodologies used in traditional software development are either inefficient to cover multimedia technology users' specific needs or not easily applicable to multimedia software development. Standards in multimedia software development tools have not been sufficiently developed to cope with the rapid development in multimedia technology and the continuous increase in users' demands and requirements. The lack of appropriate standards in multimedia software development methodologies and tools concerns the development and use of multimedia software and interests all multimedia technology community, especially multimedia software developers, producers and users. The main objective of the MediaNet Project is to mobilise multimedia technology users in a wide geographical area in and outside Europe to pursue the lack of appropriate standards in multimedia software development methodologies and tools. Specifically, the project will produce a mid-term and a final report which summarise the results obtained from users communication and include proposed solutions to alleviate or overcome the specific problem. At the end, the consortium will investigate possibilities and initiate actions to preserve the users network after the completion of the project.ACTIONSThe members of the Network are multimedia technology users, either organisations, associations or individuals, composed of main-interest and special-interest users. Main-interest users are those who use multimedia software development tools to develop multimedia software, whereas special-interest users are those who are involved in specific phases of multimedia production or directly use the results of multimedia software
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The Four Freedoms of the EU Internal Market: Is the Free Movement of Persons More Basic?' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

EUFREEDOMS examines the philosophical underpinnings of the four fundamental freedoms of the EU single market (the free movement of goods, persons, services, and capital). While the legal literature on the four freedoms is huge, much less effort has been made to analyse the freedoms in philosophical terms. Philosophical debates have focused predominantly on the free movement of natural persons. Yet, there are many interesting questions about all the freedoms. How can we best interpret the rights protected by the freedoms? Which kind of justifications should be given of the four freedoms? How are EU citizens benefited by having each of the freedoms? How should we understand the relationships between the freedoms? is there a hierarchy between the freedoms? Is the free movement of persons worthier of protection than the free movement of capital? How should we handle conflicts between the freedoms and other values (e.g. social rights)?  EUFREEDOMS is an interdisciplinary project that contributes to the political theory literature of the EU with an analysis of the philosophical foundations of the four freedoms, which will contribute to shed light on the nature of the rights protected by the freedoms, and hence also on the possibility of establishing a hierarchy between the freedoms, arguing that the free movement of persons is more fundamental than the other freedoms: indeed, that it should be considered a basic right. EUFREEDOMS aims to shed light also on the way in which the four freedoms should be balanced with other considerations (e.g. social rights). There are many areas where EUFREEDOMS can have considerable impact: for example, it can contribute to a better understanding of the shape that EU integration should take in the future, and to better legitimising the four fr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The Roots of the European Intellectual Lexicon through Ramon Llull's Multilingual Vocabulary' under Horizon Europe.

assistant: **Concept**

The dissemination of the intellectual lexicon in Europe occurred thanks to the development of universities and the vulgarisation of knowledge. The LEXLlull project aims to analyse the origin and relationship between these two phenomena through the extraordinary production of the Catalan writer Ramon Llull (1232-1316), who was in contact with the academic world of his time and aspired to spread the epistemological system he had created (i.e. the Art) to all strata of society.The project envisages the creation of a multilingual (Catalan, Latin, French and Occitan) online dictionary based on the works and translations that circulated when the author was alive, and a monographic study of the scientific vocabulary used in the different languages in relation to the study centres he frequented and the different audiences he addressed. In this way, it is possible to obtain a synchronic source of the medieval European scientific lexicon in the main Romance languages and to understand how laymen could acquire this knowledge.


**Keywords:** Ramon Llull, Translation Studies, Lexicography, European Intellectual Lexicon
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'JOINT CONFERENCE ON TELEMATICS FOR HEALTH EUROPEAN UNION - SOUTH AFRICA 1996'.

assistant: **Concept**

HEAL SA has centred on a joint EU/South Africa user type, diffusion conference (Johannesburg, May 1996) to see how telematics may alleviate complex health problems in South Africa, including difficulties faced by the elderly and disabled. Since specialised healthcare is concentrated in urban areas, an improved access to these services via the vehicle of telemedicine could make a major impact on improving equity and quality of healthcare. The conference provided also a forum for discussion and exhibition of telematics products and services. It should be an important first milestone in the context of an emerging and mutually beneficial collaboration.A joint European Union/South Africa diffusion conference on Telematics for Health will be held in South Africa between 18 and 20 April 1996, near Johannesburg. This will examine the manner in which state of the art" telematics (telecommunication and information technologies) can provide solutions to the complex health problems of South Africa and of the region and improve the quality of life of disabled and elderly people. The key to rational health service provision at district, provincial and national levels is ready access to reliable data. Thus the creation of a national health information system is one of the highest priorities of the South African Department of Health. The socio-economic integration and independent living of disabled and elderly persons through the use of appropriate technology is also an important objective. The conference, with an expected attendance of 200 people from numerous European and African countries, provides a vehicle for a productive exchange of experiences between Europe and South Africa on matters ranging from standardised and integrated electronic patient health care records through to ha
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Combining catalysts design and reactor engineering to enhance the electrochemical synthesis of ammonia' (Eelctro-Ammonia), addressing dissemination and exploitation.

assistant: **Impact**

In 2020, the total global production of ammonia is up to 144 million metric tons via the Haber-Bosch process that is energy-intensive in that it requires a substantial driving force (e.g. 500 oC and 200 atm) to break the highly inert N-N triple bond, which consumes 1-2% of the worlds annual energy output and generates over 1% of global carbon dioxide emissions. The electrochemical nitrogen (N2) reduction reaction (NRR) has attracted much attention to circumvent the carbon-intensive Haber-Bosch process because of the decreasing renewable electricity prices. In contrast to the Haber-Bosch process that produces ammonia in large and centralized factories, the electrocatalytic route can achieve on-site ammonia synthesis in small-scale devices with the expectation to reduce the price of fertilizer and realize a neutral carbon footprint. However, electrochemical ammonia synthesis suffers from extremely low partial current density and Faradaic efficiency towards ammonia in aqueous conditions due to the competition of the hydrogen evolution reaction (HER). There are two challenges to NRR in aqueous conditions: (1) the HER competitive reaction is much faster than NRR in kinetics and the activation of N2 is therefore difficult, (2) low solubility of N2 in aqueous electrolytes. To overcome the challenges mentioned above, in this project, I aim to combine electrocatalysts design (i.e. suppress the HER and activate N2) and electrochemical reactor engineering (i.e. overcome the mass transport limits of N2) to improve the ammonia yield rates and current efficiency. Theory-guided preparation of singe-atom catalysts and diluted surface alloy will be performed in flow-cell/MEA electrolyzers (i.e. designed three different setups) to obtain a clear structure-activity relationship with the a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Energy efficient COmmunity STimulation by use and Integration of Local Energy Resources' (ECOSTILER) under Sixth Framework.

assistant: **Objectives**

ECOSTILER is all about a coordinated approach in achieving energy efficient communities. The common and main element is the use of biogas and district heating systems, successful tools in reduction of primary fuel consumption and CO2 reduction. The interesting complementarity is the size of the community, ranging from large to small. Amsterdam New West, a community of about 50000 dwellings, is going to reduce its CO2 emission by 50% upon completion of the redevelopment in 2015.Demand-side reduction, PV and innovative urban-bound wind energy systems count for about 30%, 20% is achieved by district heating. A new aspect here is the use of biogas coming from sewage treatment in the waste-to-energy plant. By integration of the two, energy efficiency of the biogas is increased from 50% to over 90%. The housing corporations are committed to a building standard that goes significantly beyond legal requirements. Energy efficiency in all activities is stimulated by the city council.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Immunological mechanisms of t cell activation by dendritic cells: a novel strategy for immune intervention'.

assistant: **Concept**

The use of dendrite cells (DC) as natural adjuvant has been proposed. Aim of this project is the delivery of new therapeutic treatments of human papillomavirus (HPV) injection. The proposed strategy torn immune cell therapy is based on the use of dendrite cells (DC), which are known to be the most powerful professional antigen presenting cells of the immune system, able to prime and activate antigen-specific immune responses. The most relevant objectives are:1) the generation of vectors for appropriable delivery of viral antigens to DC;2) the generation of modified DC;3) the evaluation of safety and efficacy of modified DC therapy in pre-clinical model of virally-inducedtumors;4) Pilot clinical trial of HPV patients with antilogous DC loaded with HPV antigens. This project aims to generate a novel therapeutically strategy which requires a broad interdisciplinary approach. The proposed DC-based therapy demands the generation and validation of new therapeutic tools. One SME will contribute to the pre-clinical studies in order to be in a favourable position to exploit the results of the project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The Internet Of Historical Things And Building New 3D Cultural Worlds' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

DigiArt seeks to provide a new, cost efficient solution to the capture, processing and display of cultural artefacts. It offers innovative 3D capture systems and methodologies, including aerial capture via drones, automatic registration and modelling techniques to speed up post-capture processing (which is a major bottleneck), semantic image analysis to extract features from digital 3D representations, a “story telling engine” offering a pathway to a deeper understanding of art, and also augmented/virtual reality technologies offering advanced abilities for viewing, or interacting with the 3D models. The 3D data captured by the scanners and drones, using techniques such as laser detection and ranging (LIDAR), are processed through robust features that cope with imperfect data. Semantic analysis by automatic feature extraction is used to form hyper-links between artefacts. These links are employed to connect the artefacts in what the project terms “the internet of historical things”, available anywhere, at any time, on any web-enabled device. The contextual view of art is very much enhanced by the “story telling engine” that is developed within the project.  The system presents the artefact, linked to its context, in an immersive display with virtual and/or with augmented reality. Linkages and information are superimposed over the view of the item itself. The major output of the project is the toolset that will be used by museums to create such a revolutionary way of viewing and experiencing artefacts. These tools leverage the interdisciplinary skill sets of the partners to cover the complete process, namely data capture, data processing, story building, 3D visualization and 3D interaction, offering new pathways to deeper understanding of European culture. Via its three