RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'EuropeaN Energy balance Research to prevent excessive weight Gain among Youth' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Objective: The ENERGY proposal addresses HEALTH-2007-3.3-1: Promoting healthy behaviour in children and adolescents. It will be specifically focussed on promoting health behaviours that contribute to prevention of overweight and obesity among children and adolescents.  Strategy: The project will use a multidisciplinary analysis of determinants and intervention schemes on extrinsic and intrinsic factors determining specific nutrition and physical activity behaviours in children and adolescents in different populations and regions. This in order to develop an evidence and theory-based new scheme to prevent unnecessary weight gain among youth in transition from childhood to adolescence. The new intervention scheme will be school-based and family-involved, thus combining a key intervention setting (schools) with a key behavioural determining environment (family). This new scheme will be validated for improved capacity to encourage and sustain healthful eating and physical activity behaviours, and the results will be disseminated among key stakeholders including researchers, policy makers and the general population.  Methods: In 10 work packages systematic reviews, secondary analyses of existing and accessible data sets, focus group research, survey and community-trial evaluation research among schoolchildren, parents and school staff will be conducted according to state-of-the art methodology guided by an established and approved research quality handbook. Consortium: The ENERGY project consortium spans the necessary multidisciplinary variety of experts such as public health experts, epidemiologists, nutritionists, physical activity experts, health promotion experts, paediatricians, psychologists, economists, totalling 14 partners, from 11 countries representing all regions
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Technology roadmap of processes and materials for organic electronics' under Seventh Framework.

assistant: **Concept**

The overall objective of PolyMap is to strengthen the position of Europe as the leading force in organic electronics (o.e.) worldwide. For that purpose, PolyMap undertakes 3 actions:1)      Mapping public funding in o.e. and setting up an ERA-NET (WP1).This task will be coordinated with the European stakeholder working group 1.Following to an analysis of public funding in national and regional programmes throughout Europe, we will launch a series of round tables between the involved regional and national bodies to identify opportunities for trans-national cooperation. We will culminate in setting up an ERA-NET of o.e.2)      Open source database.PolyMap will set up an open database with regard to Large Area and Organic Electronics, containing information regarding materials, key technology bricks, devices, standardisation and applications. This is closely coordinated with other EU projects (Opera, Prodi, Polynet) and with the oe-a.3)     Supporting SMEs: SMEs are essential in the European research and industry area. In WP3 we propose to support SMEs, in coordination with the Opera project. We will analyse their specific needs, prepare a service and consultancy package and propose these services to SMEs.PolyMap is an essential member of the European house of o.e. imagined by the EC. Together with three other European projects Polynet, Prodi and Opera, it forms the quadriga" which, led by the EC, will help Europe to build its advance in organic electronics."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Intersectional Contract. Understanding the Intersection of Gender and “Race”/Ethnic Inequalities in the Care-Domestic Sector in the UK by Means of Racial-Sexual Contract Analysis' (INTERSECTINGCONTRACT) under Seventh Framework.

assistant: **Objectives**

The 2007 EC Report “Tackling Multiple Discrimination” addressed for the first time at the EU level the issue of intersectionality, an approach that seeks to understand several forms of discrimination (based on gender, “race”/ethnicity, class and so forth) as the results of intersecting biases rather than of single sources of inequality. This represents a significant step towards increasing awareness of the interrelation of different types of discrimination, enabling policy makers to tackle it in a more effective manner. This research project, using an interdisciplinary approach that combines intersectionality theory and “racial-sexual contract” analysis, aims to contribute to this debate by focusing on gender and “race”/ethnicity biases in the care-domestic labour sector in the UK. It is of the greatest importance to consider the combined impact of gender and “racial”/ethnic factors on a labour market that has witnessed dramatic growth in the participation of women of ethnic minority background across all EU Member States in recent years. The study of the care-domestic sector in the UK is of particular interest due to the more advanced and articulated character of this phenomenon in the UK, and the responses it has elicited on both the policy and theoretical level. The research project introduces the new concept of “intersectional contract” and operationalizes it for empirical research. A mixed-method approach is employed, including the gathering of quantitative data, qualitative in-depth interviews with key actors (domestic placement agencies’ owners, employers, employees and policy makers), and critical discourse analysis of regulations and policy documents. This research project will consolidate the researcher’s profile as an expert sociologist of gender and migratio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Nanoscience Foundries and Fine Analysis - Europe|PILOT'.

assistant: **Concept**

NFFA-EUROPE PILOT (NEP) aims at expanding and consolidating the operation of a Interoperable Distributed Research Infrastructure for Nanoscience (IDRIN) supporting research on materials and functional systems at the nanoscale and at the microscale. NEP provides a unique overarching offer of experimental and theoretical facilities to be combined to suit user needs ranging from materials synthesis, growth, nanofabrication to nanocharacterization, microscopy and spectroscopies also with fine analysis methods at large scale X and neutron radiation sources, and to numerical simulation. The model IDRIN fostered by NEP builds on the four-year experience of transnational access provision of NFFA-Europe that delivered combined scientific services to over one thousand European users. NEP expands the catalogue of facilities with new offer of cleanroom services, high-end electron microscopy, unique 50-100 fs sources for optical and electron spectroscopies, Free Electron Laser beamlines and chemistry based mesoscale material science. An overarching metadata and data management tool (Metastore) will realize the interoperability of the NEP results and a unique open access archive of FAIR nanoscience data to merge with the EOSC. The multi-technique character of the NEP user proposals leads to advanced reproducibility of results, research goals and effectiveness in multi-disciplinary research for curiosity driven, mission-oriented and application-oriented projects by academic or industrial users. The transnational access is proposed in modalities that help coping with the post COVID-19 conditions of restricted user mobility: interactive remote access (IRA) will be available from the beginning in some TA facilities and will be further generalized through the Joint Activities along with i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'The Picture Pile Platform', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

There has been tremendous progress in artificial intelligence (AI) in many different fields due to improved machine learning algorithms, advances in computing power and the availability of big data. With machine learning platforms like TensorFlow (Google), PyTorch (Facebook), Azure (Microsoft) or CoreML (Apple), researchers and application developers can now use AI for applications such as computer vision. While there are many image databases available such as Imagenet, which can be used to train machine learning algorithms to recognize a set of generic categories, e.g., cats, there is still a lack of image databases containing more specific features of interest, e.g., crop types. Moreover, there is currently no platform that offers a streamlined, standardized approach to setting up and running an image classification campaign to ingest the millions of photographs currently collected by many people around the world. The value proposition of the ERC PoC Picture Pile Platform (PPP) is to develop an innovative, commercially self-sustaining platform that uses the crowdsourcing game Picture Pile to rapidly classify images for machine learning purposes. After a pile of images has been sorted, the image classifications will be made publicly available. A number of premium services will be added to the Picture Pile Platform, which will make the platform self-sustaining. Campaign creators will be able to pay the crowd (with a small share paid to the Picture Pile Platform) for sorting the images. Paid advertisements will be possible through our social media channels as well as paid for space on the main Picture Pile page to attract more users. For a small fee, users will be able to use the Picture Pile Cloud for specific computer vision tasks using the machine learning models that
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Deciphering cellular and viral determinants of lytic HSV-1 infection, latency and reactivation' in the context of a Horizon Europe call.

assistant: **Objectives**

Herpes simplex virus 1 (HSV-1) is an important human pathogen which infects the majority of the world`s population and inflicts a substantial burden of disease. Over the past 10 years, systems biology approaches, to which my lab has provided seminal contributions, have substantially broadened our understanding of the complex interaction of this common pathogen with its human host. However, the underlying molecular mechanisms remain poorly understood and their importance for virus latency and reactivation remain elusive. Furthermore, currently available technology lacks the temporospatial resolution to decipher the cellular and viral determinants that govern the virus life cycle. The main goal of DecipherHSV is to close these knowledge and technology gaps and decipher novel mechanisms and their functional interplay by which HSV-1 manipulates its host cells throughout the virus life cycle. Accordingly, the three primary objectives of DecipherHSV are to: (i) decipher the full complement of viral elements that govern productive infection; (ii) decipher how and why HSV-1 manipulates pervasive transcription within the host and viral genome; and (iii) decipher the cellular and viral determinants of HSV-1 latency and reactivation. Alongside, I will develop new computational approaches and integrative analysis tools, and employ artificial intelligence to exploit the wealth of information that is provided by the novel single cell RNA sequencing approaches, which I will pioneer (Heterogeneity-seq and Perturb-scSLAM-seq). Thereby, I will deliver new leads for novel therapeutic approaches targeting HSV-1 latency and reactivation. This will provide a paradigm for the study of other herpesviruses and their complex host-pathogen interactions.


**Keywords:** Herpes simplex virus 1,  la
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'What determines the hierarchy of VSG antigen switching in T. brucei?' to be submitted under Horizon Europe.

assistant: **Abstract**

Pathogens use antigenic variation to evade host antibodies and cause diseases in humans. Interestingly, in many species antigen switching occurs non-randomly in a hierarchical manner, with specific antigen genes selected in succession. Trypanosoma brucei is a key model organism for the study of antigenic variation in which antigen switching hierarchies of its Variant Surface Glycoprotein (VSG) genes operate. However, how exactly this hierarchy is determined is unknown. Studies in T. brucei have indicated that the spatial positioning of VSG genes within the nucleus is important for controlling their activation. However, to date no systematic investigation of VSG gene nuclear positioning and antigen switching hierarchies has been performed. In this project, I would test the hypothesis that antigen switching hierarchies in trypanosomes are mediated by the spatial positioning of VSG genes in the nucleus.  Using T. brucei cell lines in which different antigen switching pathways can be induced, I will determine whether silent VSGs in close spatial proximity to the active VSG before switch induction are selected next in the antigen switching pathway. This will be investigated by integrating a combination of Micro-C to monitor VSG nuclear positioning before and after switching followed by scRNA-seq. I will also develop a dCas9 artificial tethering system to tether silent VSGs either towards or away from the active VSG before switch induction to create a synthetic VSG switching hierarchy. These experiments will generate important insights into the mechanisms which control antigen switching and provide valuable tools for studying nuclear organisation in kinetoplastid parasites.


**Keywords:** Antigen switching, NGS technologies, CRISPR, Cas9
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'European Design Innovation Tool'.

assistant: **Concept**

To strengthen the knowledge of design management in SMEs and provide with a common approach to create the necessary awareness among SMEs and design promotion agencies at European level.The work programme has the following tasks:- Elaboration of a common methodology, and identification of selected design best practices.- Training workshop.- Evaluation of results and refinement of the methodology for dissemination.- Creation of dissemination tool and material. Three types of media will be designed as a base for the dissemination phase: a seminar / workshop concept, written material and Internet Web site. A periodical newsletter called EDIT-News will be launched at European level with main project results and events of design management. - Dissemination at the national and European level. results and methodology will be disseminated through more than 35 seminars. Two major events will be organized: a presentation to design centres and promoters (Eindhoven) and a Design Conference in Stockholm.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'PUBLISHERS ON INFORMATION HIGHWAYS' (POLLEN).

assistant: **Concept**

The aim of POLLEN is to support European publishers of interactive educational materials in developing and testing production methods for the design of multimedia materials in the sciences for large public audiences. The materials will be delivered via off-line (CD-ROM) and on-line (interactive TV) channels. The choice of production and delivery methods will take into account the numerous constraints of time, quality and cost. The research-based collaborative production will be tested and validated with two prototypes in the science domain. Both of which will be designed for on-line and off-line delivery and will be demonstrated in real life situations in France and Germany.The overall aim of the POLLEN project is to support European publishers of interactive learning materials to develop and test production methods for designing multimedia educational materials, in the domain of science, for large public audience, that can be delivered through off-line and on-line channels, taking into account the numerous constraints of time, quality and costs imposed by commercial publishing.A methodology for the collaborative design and the production of specification will be developed based on results coming from didactic research. The method will be tested and validated thanks to the prototyping of two products in the domain of science, each of them being implemented for on-line and off-line delivery.The project will have two demonstrations in real-life situation in the region of Stuttgart, and in the region of Ile-de-France.The main anticipated results are: a practical method to create and specify interactive learning materials; two pieces of educational multimedia software, in three languages, which could be exploited as elements of CD-ROMs to be commercialized; quantitative and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Multi-Robot Cognitive Systems Operating in Hospitals' (MOnarCH), addressing dissemination and exploitation.

assistant: **Impact**

MOnarCH targets (i) the development of a novel framework to model mixed human-robot societies, and (ii) its demonstration using a network of heterogeneous robots and sensors, in the pediatric area of an oncological hospital. It will handle uncertainties introduced by people and robots, generate natural interactions, and engage in edutainment activities.The expected outcomes are (i) an operational system able to interact with people in a natural way, (ii) novel results on key properties of networked robot systems, and (iii) guidelines to translate the system to applications in hospital environments, and further scenarios sharing similarities with them, e.g., kindergarten, and personal assistance to elderly at home.Innovation is expected mainly in (i) the modeling and analysis of the dynamics of social organizations, and social individuals, (ii) the mapping between such models and implementable systems, (iii) the integration between models related to social and asocial behaviors, (iv) the introduction of creative methods of interaction between people and robots, based on models of the dynamics of social organizations and individuals, and (v) the adaptation of robots to individuals and groups of people. This framework will map concepts in social sciences into social skills, group behaviors, and human-robot interaction, using learning methodologies and decision-theoretic principles.Functional tests will be executed using the networked robotics environment at IST and other partners. Technologies such as a network of fixed cameras, RFID tags, teleoperation devices, voice generation, both isolated and combined as augmented reality interfaces, will be used. Specific tests will be carried out in a real hospital, at IPOL.The Consortium is formed by research institutions, SMEs, an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Transgenic animal models to study diabets mellitus' in the context of a Fourth Framework call.

assistant: **Objectives**

All forms of diabetes are characterized by hyperglycemia, development o diabetes-specific microvascular pathology and macrovascular complications. For example, as a consequence of the microvascular pathology, diabetes is now the leading cause of adult blindness. Until now, a clear understanding of the basic pathogenic mechanisms of diabetes has not yet emerged, but the generation of transgenic animal models may give the key to curing the disease.  Fatima Bosch's group has recently obtained transgenic mice that express IGF-I in pancreatic beta-cells. Preliminary results indicate that these animals are diabetic. In addition, these mice develop the long-term complications of the disease (cataracts, glaucoma, retinopathy). These mice constitute the first animal model that naturally develops ocular complications of diabetes mellitus.  In this project, using these transgenic mice, I will study the role of IGF-I in the pathogenesis of diabetes mellitus and the mechanisms leading to development of secondary complications. Furthermore, it has been described that IGF-II, like IGF-I, is able to suppress insulin release. I will obtain another transgenic animal model, overexpressing IGF-II in beta-cells, to study if this factor is also able to alter insulin secretion in vivo and lead to diabetic complications.  In conclusion these mice will be used to investigate the mechanisms leading to development of secondary complications and they will also be used to design new therapies to abolish the serious long-term complications of diabetes mellitus.