RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Intermodal Portal Task 2.3.2/2 innovative Waterborne Transport Concepts'.

assistant: **Objectives**

The IP Project will improve the integration of ports into intermodal transport chains by harmonising administrational procedures and offering a set of information and communication (ICT) tools and services for easing the mandatory data supply as well as the data delivery to other partners in the chain. This will be done by integrating results of previously successful RTD projects and industrial strength solutions into a large scale demonstration covering 20 of the major seaports all over Europe (from Finland to Greece). IP is a combined RTD/Demonstration project for the Task 2.3.2/2 ""Innovative Waterborne Transport Concepts"" of the 1st Call for the 5th Framework Programme, Thematic Programme ""Competivite and Sustainable Growth"", Key Action ""Suistainable Mobility and Intermodality""."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Smart Ordering Plan as a Service', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Knowing how much to order and when is a longstanding industrial problem called order planning.  The 2 main approaches are:1. Upfront ordering. Allows capturing quantity discounts and simplifying operations, but causes high inventory costs (e.g. space, amortisation).2. Just-in-time ordering. Minimises inventory costs, but requires a higher quality control, increases order fees and reduces discounts on quantities.However, the right solution lays in the grey area in-between. Sometimes part of the inventory might go bad after a certain time and forces frequent ordering, storage space might be limited, suppliers might impose minimal order amounts, may be some material has long lead times. In summary, a myriad of real-world considerations that current solutions ignore, achieving only partial optimisations.GenLots’ SOPaaS is a Software-as-a-Service (SaaS) solution that untapped savings in the ordering plan (OP) elaboration stage of Supply Chain Management (SCM) process thanks to our machine learning based algorithms. In short, SOPaaS optimally answers the question: “When do I need to order and how much raw material?”Our proprietary machine-learning algorithms unlocks untapped savings of 5-10% of total purchasing cost on average. This translates in millions of euros saved for our clients, a unique value proposition that guarantees their willingness to pay. SOPaaS solves the theoretical problem of obtaining the ordering plan, while also considering real-world factors in various dimensions, e.g. cost (e.g. lots’ shelf life, associated storage cost), sustainability (e.g. prefer eco-friendly shipments) or responsibility (e.g. fair trade considerations) among others.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Catalytic Dual-Function Devices Against Cancer', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Despite intense research efforts in almost every branch of the natural sciences, cancer continues to be one of the leading causes of death worldwide. It is thus remarkable that little or no therapeutic use has been made of a whole discipline, heterogeneous catalysis, which is noted for its specificity and for enabling chemical reactions in otherwise passive environments. At least in part, this could be attributed to practical difficulties: the selective delivery of a catalyst to a tumour and the remote activation of its catalytic function only after it has reached its target are highly challenging objectives. Only recently, the necessary tools to overcome these problems seem within reach.CADENCE aims for a breakthrough in cancer therapy by developing a new therapeutic concept. The central hypothesis is that a growing tumour can be treated as a special type of reactor in which reaction conditions can be tailored to achieve two objectives: i) molecules essential to tumour growth are locally depleted and ii) toxic, short-lived products are generated in situ.To implement this novel approach we will make use of core concepts of reactor engineering (kinetics, heat and mass transfer, catalyst design), as well as of ideas borrowed from other areas, mainly those of bio-orthogonal chemistry and controlled drug delivery. We will explore two different strategies (classical EPR effect and stem cells as Trojan Horses) to deliver optimized catalysts to the tumour. Once the catalysts have reached the tumour they will be remotely activated using near-infrared (NIR) light, that affords the highest penetration into body tissues. This is an ambitious project, addressing all the key steps from catalyst design to in vivo studies. Given the novel perspective provided by CADENCE, even partial
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Identifying Clinical, Demographic, and Genomic Risk Factors for Treatment-Resistant Psychiatric Disorders' (ClinGen-PsychTx) targeting Horizon 2020.

assistant: **Abstract**

Identifying factors contributing to treatment-resistance in psychiatric disorders could uncover shared aetiology or used to develop predictive tests to identify patients at risk of poor outcomes. Severe psychiatric disorders–here schizophrenia, bipolar disorder, major depressive disorder, and anorexia nervosa–have an enormous impact on morbidity. Up to 60% have poor outcomes despite adequate treatment. Those with treatment-resistant psychiatric disorders have high rates of mortality, higher health care costs, and are hospitalized longer. Further knowledge on how clinical, demographic, and genomic factors effect treatment-resistance in psychiatry is urgently needed. To date, I am unaware of any systematic assessment of genetic, clinical, and demographic factors associated with treatment-resistance across the 4 previously mentioned disorders simultaneously. Previous genomic studies investigating these disorders evaluated treatment-resistance for one disorder, were limited by small sample sizes, and did not consider a range of risk factors. First, I will investigate whether clinical and demographic factors are associated with treatment-resistant psychiatric disorders using Swedish National register data and whether they differ between disorders (N=20K). Second, I will examine whether different forms of genetic variation are associated with treatment-resistance, using existing samples (N=20K) with genome-wide genotyping, copy number variant, and exome data. Here, I will uncover knowledge about how genetic variation effects treatment-resistance, including shared genetic correlation. Third, I will examine the confounding effects of genetics on clinical and demographic factors for treatment-resistance. Completion of the proposed work could highly impact our understanding of tr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Politics of Welfare in Emerging Market Economies' (WELFAREPOLITICS).

assistant: **Concept**

The research aims at explaining contemporary welfare system transformations in emerging market economies during the last four decades, by considering grassroots political factors. Through a comparative and historical analysis of welfare systems in Brazil, South Korea and Turkey, this project will examine to what extent grassroots politics have shaped welfare policies, focusing on government efforts to contain social unrest and mobilize popular support with the use of social welfare provision. There are two specific hypotheses: Despite similar structural transformations, (i) since the 1990s, Brazilian and Turkish governments have prioritized social assistance programs for the poor over social security programs for employees as a political response to a shift in grassroots politics from the formal to the informal proletariat, (ii) In South Korea, social security programs have remained as the central form of welfare provision because the formal proletariat has continued to act as the fundamental grassroots power. The informal proletariat has become the main source of threat and support for governments under the influence of Islamic and Kurdish movements in Turkey and under the influence of drug traffic in Brazil that controls the Afro-Brazilian dominated favelas. In South Korea, the formal proletariat has still been mobilized largely by powerful trade unions in. Thus, Brazilian state has to deal with criminal organizations and Turkish state with radical political organizations that both radicalize the informal proletariat while South Korean State with labour organizations. Welfare provision has been a critical instrument for government efforts in all cases and the type of grassroots political force that states mainly have to deal with has determined the central type of wel
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Assessment methodologies for forward looking Integrated Pedestrian and further extension to Cyclists Safety Systems' (ASPECSS) targeting Seventh Framework.

assistant: **Abstract**

According to the World Health Organisation Global status report on road safety 2009, pedestrians account for more than 19% of road fatalities in the EU-27. It is well known that most accidents with pedestrians are caused by the driver being in alert or misinterpretation of the situation. For that reason advanced forward looking integration safety systems have a high potential to improve safety for this group of road users. These systems combine reduction of impact speed by driver warning and/or autonomous braking with protective devices upon impact.Previous EU research projects resulted in systems which are gradually entering the market. However, such new systems have to be widely deployed in the marketplace to realise their potential benefits.The objective of the AsPeCSS  project is to contribute towards improving the protection of vulnerable road users, in particular pedestrians and cyclists by developing harmonized test and assessment procedures for forward looking integrated pedestrian safety systems. The outcome of the project will be a suite of tests and assessment methods as input to future regulatory procedures and consumer rating protocols. Implementation of such procedures / protocols will enforce widespread introduction of such systems in the vehicle fleet, resulting in a significant reduction of fatalities (30% pedestrians; 20% cyclists) and seriously injured (50% pedestrians; 20% cyclists) among these vulnerable road users.Activities are in line with objectives set in the Communication from the Commission to the European Parliament, the Council, the European Economic and Social Committee and the Committee of the Regions: “Towards a European road safety area: policy orientations on road safety 2011-2020”. In this communication the Commission proposes to targ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'For a sustainable and european value chain of PHA-based materials for high-volume consumer products' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Plastic is one of the preferred materials for manufacturing high volume consumer products and more particularly packaging thanks to its physical, mechanical, thermal or barrier properties. However, existing global plastic industry is mainly a petrochemical-based industry, bringing bad environmental footprint. Polyhydroxyalkanoates (PHAs) are a group of biopolymers that are now widely recognized as attractive substitutes to fossil fuel derived plastics in a wide range of applications. Unfortunately, no sustainable value chain exists in Europe, and production schemes developed elsewhere in the world appear highly questionable from an environmental and ethical standpoint.The NENU2PHAR project aims at bridging this crucial gap in the EU industry, within an inclusive approach that will address the whole PHA-based plastic value chain, targeting high volume consumer products. The NENU2PHAR project gathers 17 partners (5 large industrials, 6 SMEs, 5 RTOs and 1 cluster), leaders in the different fields of research, from biomass development to formulation of biopolymer up to plastic processes. First, bio-source will be tackled by developing and optimised production of PHA biopolymer thanks to the optimisation of carbon feedstock from micro-algae biomass and selection of bacteria strains. Then, innovative polymer processing options will generate different structures with various bulk-surface properties, and various end of life properties. Market uptake of this new PHA will be supported by a competitive cost (5/kg for PHA compounds), high purity product and processes optimised for PHA bioplastic to tackle functional properties of high volume consumer product better than fossil-based counterparts.8 PHA-based products will be developed and benchmarked to their fossil-based counterpar
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Early market introduction of new energy technologies in liaison with science and industry' (EMINENT) targeting Sixth Framework.

assistant: **Abstract**

The strategic objective of EMINENT is to strengthen the European industry and policy institutions by establishing and operating a network that assesses results from science and technology research for the purpose of enhancing and accelerating the market introduction of energy technologies.This objective of EMINENT will be met through:-Promotion and dissemination of results of research and demonstration projects in energy technologies relevant to different regions;-Complement and strengthen dissemination activities carried out within individual FP5 and FP6 projects;-Combination of results from different projects and make (objective and unbiased) assessments of the technologies with the highest market potential as a basis for a thematic approach to promotion and dissemination;-Cutting lead-time for enabling technologies by securing the right means and measures when needed;-Bridging the gap between European R&D centres and the European energy technology industry;
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'COntrolling and progressively Minimizing the Burden of Animal Trypanosomosis' under Horizon 2020.

assistant: **Concept**

Animal trypanosomosis (AT) is caused by parasites transmitted by tsetse and other blood-sucking flies. The disease is a scourge for livestock keepers in Africa , affects humans  and could spread to Europe . COMBAT aims to reduce the AT burden in Africa using the concept of progressive control pathway (PCP) . The PCP is an innovative, risk-based approach to disease reduction or elimination through successive, achievable steps. A consortium of excellence, with European and African research institutes, national veterinary authorities from across Africa, and leading international organizations guarantees successful project implementation and maximal impact on the SDGs. COMBAT will 1) improve basic knowledge on AT; 2) develop innovative control tools; 3) improve surveillance and control strategies; and 4) build capacity and raise awareness. Knowledge gaps on epidemiology, chemical ecology, vector competence, and immune and metabolic aspects of tolerant livestock will be filled. Innovative tools include environmentally friendly vector control technologies and electronic antigen capture tests. Surveillance will be enhanced by establishing information systems, strengthening reporting, and modelling risk in Africa and Europe. The socio-economic burden of AT will be assessed. Guidelines for national control strategies will be developed and implemented. COMBAT will draw on the extensive partners’ experience in other EU projects and strengthen existing partnerships in the field of AT control.


**Keywords:** Animal Trypanosomosis, tsetse fly, livestock, susceptibility, eco-epidemiology, surveillance, diagnosis, vector control, risk cartography, host-parasite interaction, socio-economic, vector competence
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'MARINE ENVIRONMENT TESTS AND RESEARCH INFRASTRUCTURE - 2' to be submitted under Sixth Framework.

assistant: **Abstract**

Under this contract, access for user groups will be provided to the Infrastructure entitled Marine Environment Test and Research Infrastructure (METRI). This Infrastructure, located at Brest and Boulogne-sur-mer in France is owned and operated by IFREMER, the French Research Institute for Sustainable Sea Exploitation.Within the Infrastructure, access will be made available to the five following installations.- the deep wave testing basin,- the water circulation testing basin,- the hyperbaric testing tank laboratory,- the material behaviour testing laboratory - the marine sensor evaluation laboratory.During the contract duration, it is expected that 20 short-term projects will be selected and that a minimum of 40 users will benefit from access to this Infrastructure. The total number of experimental days to be provided is 200 for the five installations. This access will be provided free of charge to the user groups given access to the Infrastructure under this contract and will include all logistical, technical and scientific support that is normally provided to external users of the Infrastructure.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Deciphering type 2 innate lymphoid cell/epithelial progenitor cell crosstalk in pancreas regeneration and neoplasia' (PanILC).

assistant: **Innovation**

Regulation of the epithelial stem cell compartment is critical for tissue homeostasis and regeneration. Consequently, imbalance in this process, through acquisition of somatic mutations for instance, may give rise to tumorigenesis. Emerging reports reveal that regulatory T cells (Tregs) can modulate epithelial stem cell dynamics in the skin, while type 2 innate lymphoid cells (ILC2s) are known to influence tissue-regeneration. Recent work in our laboratory has elucidated that ILC2s crosstalk is essential for local Tregs expansion. We hypothesize that tissue-resident ILC2s influence the stem cell niche by recruiting and regulating Tregs, and that such a mechanism could be key to tissue regeneration as well as tumor development.Preliminary data in the lab suggest that the intraperitoneal injection of the potent ILC2 inducer IL-33 in mice activates ILC2 in the pancreas, and that a concomitant increase in Treg numbers is observed in this organ. This raises the possibility of the existence of a crosstalk between ILC2s and Tregs in the pancreas upon inflammation, such as in the case of pancreatitis. Given the considerable attention brought lately on the ability of Tregs to develop tissue-promoting capacities, we postulate that regeneration of the exocrine pancreas following pancreatitis may be driven by such pancreatic Tregs upon their “priming” by ILC2.The present project will therefore focus on understanding the role of ILC2 and Tregs and their possible crosstalk in pancreatitis development, as well as in the regeneration process that follows, i.e. the interaction of these immune cells with epithelial progenitors. As pancreatitis is a major risk factor for the development of pancreatic cancer, the resulting observations will then be extended to the analysis of the role of I