RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'CLOck NETwork Services: Strategy and innovation for clock services over optical-fibre networks' under Horizon 2020.

assistant: **Concept**

A scientific and technological paradigm change is taking place, concerning the way that very high performance time and frequency reference signals are distributed, moving from radio signal broadcasting to signal transport over optical fibre networks. The latter technology demonstrates performance improvements by orders of magnitude, over distances up to continental scale. Research infrastructures are developing several related technologies, adapted to specific projects and applications. The present project aims to prepare the transfer of this new generation of technology to industry and to strengthen the coordination between research infrastructures and the research and education telecommunication networks, in order to prepare the deployment of this technology to create a sustainable, pan-European network, providing high-performance ""clock"" services to European research infrastructures. Further this core network will be designed to be compatible with a global European vision of time and frequency distribution over telecommunication networks, enabling it to provide support to a multitude of lower-performance time services, responding to the rapidly growing needs created by developments such as cloud computing, Internet of Things and Industry 4.0.The project aims at partnership building and innovation for high performance time and frequency (clock) services over optical fibre networks and to prepare the implementation of such a European backbone network.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Experimental determination of the paraxial-vectorial limit of light-matter interactions' under Horizon 2020.

assistant: **Concept**

The aim of this proposal is to study the transition between the scalar an vectorial regimes of light-matter interactions and show that its knowledge can be used to create a chirality-discriminating device. For that, the scalar-vectorial transition will be studied for three conceptually different nanostructures. The study will be carried out with a technique developed by the ER: vortex beam-induced circular dichroism. The findings of the study will be given by means of three look-up-tables, one for each kind of nanostructure. These look-up-tables will allow any light-scientist working with similar nanostructures to identify the regime (scalar/vectorial) in which their light-matter interactions are taking place. The results of this project will improve our fundamental understanding of light-matter interactions. This knowledge will add a new dimension into the characterization of complex 2D and 3D nanostructures. To show the potential of this characterization, at the end of the project we will use the look-up-table of a 3D plasmonic vortex to design a device that efficiently discriminates the chirality of molecules.The project has all the ideal elements to fulfill its goals. On one hand, the ER is already a scientific expert in light-matter interactions at the nanoscale. On the other hand, the Plasmon Nanotechnologies group at IIT, with its world-class laboratories and clean rooms provides an extraordinary scientific environment for the ER to develop his career path. In particular, it is expected that the ER learns many different nanofabrication techniques. Thus, thanks to this action, the ER will become a preeminent scientist with a unique set of skills combining nanofabrication, optical manipulation/measurements and simulations/theoretical work. This will place him in an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Galactic cosmic RAy Propagation: an Extensive Study'.

assistant: **Innovation**

Where do Cosmic Rays (CRs) originate? How do CRs interact with the environment during their journey to Earth?GRAPES aims at revealing the origin of galactic CRs, 100 years after their discovery, by achieving the most accurate description of CR propagation in the interstellar medium (ISM). More specifically:1) What is the mechanism of propagation in the Galaxy? Measurements show fine structures in the observed CR spectra, but we have exceedingly simplified transport models. In view of the challenges that recent observations posed to conventional homogeneous CR diffusion models, we will develop the first self-consistent simulation of interstellar CR propagation, including non-linear processes, anisotropic diffusion and galactic winds.2) Where do CR become extra-galactic? Understanding propagation at the end of the galactic CR spectrum is compelling towards the identification of galactic sources. We will provide an innovative approach able to describe at once the CR spectrum and anisotropy up to the knee energy attacking the pending theoretical and observational challenges.These questions are profound, challenging and appealing and can be efficiently pursued only through a new advance in the complex numerical modeling of galactic CR transport and by establishing a tight collaboration between communities involved in CR physics.We live in exciting years, since for the first time experimental techniques allow (or are going to allow) forefront questions to be tackled with the necessary sensitivity. The enormous discovery potential is further witnessed by the fact that the two most advanced experimental projects categorized by the European Astroparticle priority roadmap are specifically tailored to map the high-energy gamma (CTA) and neutrino (KM3NeT) sky with unprecedented lev
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Optimisation and control of the freeze-drying of pharmaceutical proteins' (LYO-PRO).

assistant: **Innovation**

The aim is to optimise the freeze-drying process of pharmaceutical proteins on a scientific basis, using a new technology to control ice nucleation; an innovative piece of equipment will be realised, developing new control and diagnostic tool and new sensors. This will improve the performances and the reproducibility of the process, allowing to control the final quality of the product, increasing competitively of European pharmaceutical industry and producers of freeze-dryers. The production of therapeutic proteins in lyophilised form will be greatly improved, reducing the possibility of antigenic effects. It will be possible to design prolonged-release injectable forms of proteins using an advanced supercritical coating technology, with lower treatment cost and improvement in the patient's comfort. Another objective is the reduction of waste product in the production of serological screening tests.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Microcavity Array Supported Lipid Bilayers; Biomimetic Test Beds for Drug–Membrane Interactions', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The proposed research programme will advance the state of the art in nanostructured array preparation. This will be achieved by utilising microcavity arrays generated via standard nanosphere lithographic approaches and reproducibly introducing additional nanostructures via plasmonically directed growth. The resulting arrays will lead to greater optical signal enhancement due to the additional plasmonic coupling and focusing generated by the extra metallic structures. Importantly, these arrays will not only lead to increased plasmonic activity but will be reproducibly prepared, unlike current approaches used to enhance the activity of microcavity arrays.Nanostructured arrays of this nature can be used to enhance optical signals such as those generated in Raman and fluorescence spectroscopy. Therefore, following their development they will be used in the preparation of a novel drug permeability assay. Biomimetic lipid bilayers, representing natural cell membranes, will be supported on the arrays and the interaction of drug molecules of interest monitored via metal enhanced fluorescence, surface enhanced Raman spectroscopy and electrochemical impedance.The proposed approach will result in the measurement of a dissociation constant for specific drug-membrane combinations. This dissociation constant will be an improved parameter compared to the currently utilised partition coefficient that is measured for drugs between two immiscible liquids. An improved insight into drug-membrane interactions, such as those provided by the proposed novel drug permeability assay, will have significant impacts in the cosmetics and pharmaceutical fields. Product development will be better informed at a much earlier stage and only the most promising targets advanced to the more expensive in vit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Bone Marrow-on-Chip as smart sensor of lung cancer relapse'.

assistant: **Concept**

In the past 40 years the overall survival rate for people affected by tumors has doubled, with about 50% of patients now surviving their disease for 10 years or more. Nonetheless, some cancers (e.g lung cancer) still have poor survival rate. A major cause of lung cancer mortality is represented by disease relapse, occuring when few of the original cancer cells survive the initial treatment and causing primary tumor recurrence. Currently, no options are available to predict the risk of lung cancer relapse, which is only diagnosed late based on radiological evidence. Hence, the ability to early detect lung cancer relapse represents an urgent and unmet need, since a fast and tailored treatment could dramatically increase patients’ survival rate.BuonMarrow lays on the groundbreaking hypothesis, supported by our Consortium preliminary clinical evidence, that bone marrow mesenchymal stromal cells (BM-MSC) may be educated upon cancer mediators exposure, and acquire a long-term memory-like response which is amplified when exposed to a secondary tumor. Owing to breakthrough technologies available in the Consortium (organ-on-chip, innovative optical sensors and biological modeling of the bone marrow niche), BuonMarrow partners will develop an in vitro miniaturized bone marrow device able to harness the amplified BM-MSC response generated by liquid biopsy of lung cancer patients, thus acting as a biological sensor for the early detection of relapse. A combination of retrospective and prospective clinical studies, respectively, will allow to calibrate and validate such sensor, delivering an unprecedented tool to assist the decision-making process on lung cancer patients.We expect to significantly improve oncological treatments, building on a personalized medicine approach to increa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'A Rosetta Stone for Robust Observables of Topological States from Symmetry Group Theory' (TopoRosetta), addressing dissemination and exploitation.

assistant: **Impact**

Solid-state materials hosting topological insulating (TI) states have been intensely studied following predictions that their bulk and surface features may serve as robust platforms for spintronics, quantum computing, and magnetoelectric responses. 3D topological crystalline insulator (TCI) states protected by crystal symmetries have also been predicted, and through first-principles (DFT) calculations, thousands of candidate TIs and TCIs have been identified, including correlated charge-density-wave and magnetic variants. Though topological materials can readily be mathematically classified, we still do not know the bulk experimental signatures and advantageous properties of most topological states, limiting their practical applicability in chemistry, materials science, and quantum devices. To unlock the immense promise of solid-state TIs and TCIs, I propose to leverage the group theory of crystal symmetries to produce a Rosetta Stone to translate the mathematical topological classification into robust and intuitive experimental observables, such as the spin and charge trapped by defects and new electromagnetic responses. First, we will devise theories of topological spin-, orbital- (valley-), and layer-resolved bulk, surface, and crystal defect responses in 3D TCIs and introduce numerical methods for their identification in real materials. Next, we will for the first time construct a position-space, symmetry-based methodology for systematically enumerating and analyzing superconducting (SC) TCIs, which may host excitations advantageous to the storage and manipulation of quantum information. We will introduce the fundamentally new notion of SC symmetry groups to characterize SC TCIs by exploiting tension between their position- and momentum-space descriptions. This will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Late phase source term phenomena' under Fifth Framework.

assistant: **Concept**

A programme is proposed to quantify fission product and core materials released from molten corium. This work will examine the kinetics of release of the key fission products (as simulants), and also allow the importance of key phenomena (e.g. sparging, slag formation, two-phase systems) to be determined. There will be a series of experiments to aid with understanding the chemistry of species released during the late phase of an accident, together with experiments aimed at examining the long-term behaviour of a solidified core immersed in a water pool.The results will be used to develop generic code models for the relevant phenomena. The models and experimental results will be used in plant calculations for Eastern, Western and advanced designs. The programme will aid in the development of accident management strategies and provide data on fission product behaviour in the late phase of an accident.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The natural history museum' (SYS-RESOURCE).

assistant: **Concept**

Description:Description The Infrastructure combines both the preserved and living collections of The Natural History Museum, London (in association with The Linnean Society and Royal Botanic Gardens, Kew), which together represent Europe's leading centre for systematics-related research. 2,250 User days of access are offered to the collections. In addition, state-of-the-art specimen preparation and study facilities are provided. Specifically,225 access days in the Analysis and Imaging Facility, offering chemical analysis (including ICPAES and LA-ICPMS) and microscopy (Microprobe, SEM and TEM) and 540 access days in the Molecular Biology Unit, offering the latest technology to facilitate phylogenetic research; and the Palaeontology Conservation Unit (ca. 25 User Days), which is unique in Europe and undertakes remedial treatment on fossils. All Infrastructure Users are mentored by top-class researchers and curators.Application:Applications should be made on an on-line/Word 6 form available via the web page or in hard copy from the Project Manager. Calls for proposals are published in Cordis Focus, Research Europe, Research Fortnight and ReFund and are circulatedvia the European Association of Research Managers and Administrators (EARMA). The User Selection Panel, is chaired by Dr Rory Post (NHM). Users applications are graded according to the: - scientific excellence of the proposed research - scientific quality of the User Group - strength of the referee's supporting statement - justification given for request for access to the Infrastructure - value of the expected gains to the User and the EU's research community - quality and value of the outputs.Project manager:Vanessa Pike, Science Directorate, Cromwell Road, LondonSW7 5BD, United Kingdom.Tel: +44-207-9425530Fax: +4
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Multi-component Soft Materials Advanced Research Training Network'.

assistant: **Objectives**

MultiSMART, Multi-component Soft Materials Advanced Research Training Network, is a Doctoral Network of six Universities, one private nonprofit Research Institute, two large Companies and an SME, involving training, fundamental research and applications in the field of molecular soft materials. These have substantial societal and economic impact, but require innovation to ensure sustainable development. The primary research objectives are defined as (i) the innovation in soft materials through multi-component self-assemblies; (ii) the application of these materials in the formulation of actives with elevated performance in the large-scale industries of personal care and home care, as well as high-added value regenerative therapies. Multi-component systems based on low molecular weight gelators have considerable potential to achieve these goals with the key advantages of programmability and responsiveness. However, their development hinges upon the formation of an inter-disciplinary network with well-trained researchers. MultiSMART proposes: (1) the training of the future generation of researchers; (2) the tight integration between academic projects and private sector needs; (3) a network-wide, seamless multidisciplinary, international and inter-sectoral training that is not available at any one institution. MultiSMART will be formed around 9 hired researchers who will have the opportunity to become scientists employable in both the industrial and academic sectors. In an integrated approach, they will be trained to bridge the gap between chemistry, physics, biology and formulation technology, as well as to acquire transferable skills through their research and specifically designed network-wide schools and workshops. The participation of three industrial participants in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Virtual Open Air Museum' to be submitted under Fifth Framework.

assistant: **Abstract**

The mission of the VIRMUS project is to narrow the gap between Internet users and the on-line virtual museum displaying 3D cultural heritage content. VIRMUS aims at introducing a novel way of 3D web page development for open-air museums and other institutions displaying architectural objects. The innovative aspect of VIRMUS is the use of commercially available 3DML that enables effective supplier-content-user interaction in cultural heritage applications. 3DML emulates HTML syntax. Therefore, first-time users can create 3D pages alongside their HTML pages using the same authoring techniques, images and sounds they already know and understand. The work of the VIRMUS project will be based on data gathering and processing leading to the 3D presentation of a virtual reality museum, as well as creation of an Internet portal www.eurohistory.net disseminating the experience gained to web users.Objectives:The objective of the proposal is to provide a way for ordinary museum web masters and Internet users with limited or no knowledge of 3D generating tools to create interactive virtual environments in three dimensions.There are two basic tasks to be achieved during the VIRMUS project:1. Create a virtual museum web page interface based on 3 DML modelled spots. Each spot will represent a fraction (courtyard) of museum buildings. Hyperlinks will lead users to other pages containing 2D and 3D information.2. Establish an Internet portal (www.eurohistory.net) displaying a 3DML assembled virtual open-air museum as well as providing users with tools to create their own virtual environments of historic architecture characteristic to particular culture. VRML generated 3D objects, thematic textures.Work description:The work will be divided into three phases:1. Data gathering. The majority