RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Tumor and Lymph Node on Chip for cancer studies' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The lymphatic system and lymph nodes (LNs) are an integral part of our adaptive immune system and many tumors exploit lymphatic vessels to spread and colonize downstream LNs. Tumor-LN-oC aims to offer a comprehensive solution for a robust, automated tumor-lymph node-on-chip platform that will connect primary surgically removed human tumors and LN tissue from the same cancer patient. This will allow us to study the interaction of primary tumors with lymph nodes, identify their chemical signature, and offer personalized treatment relying on molecular characterization of lymph node metastasizing cells. The project will significantly advance the fields of microfluidics, cell biology, cancer biology, physics, and computer programming and software development, by pursuing the following objectives: a) To introduce novel designs and develop robust, automated microfluidic chips optimized for tumor cell and LN culture enabling the study of their crosstalk, b) To integrate Quantum Cascade Laser based mid-IR spectroscopy for specific chemical signatures, c) To molecularly characterize both migrating tumor-derived cells attracted to the LN and the soluble signals driving migration, d) To demonstrate an advanced image analysis and signal processing platform using deep learning algorithms facilitated by a micro-optics module to monitor in real time the cells migration, e) To integrate all Tumor-LN-oC technologies in an automated platform prototype incorporating interfaces compatible with existing laboratory equipment. The Tumor-LN-oC platform, will be developed at TRL5 and will be validated using real patient samples. Regulatory pathways, standards and requirements compliance will be considered in order to facilitate exploitation and early market entry. The consortium encompasses key
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Modelling Nonlinear Aerodynamics of Lifting Surfaces' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The performance-improvement objectives sought in the Clean Sky 2 Joint Undertaking requires a departure from conventional empennage configurations and technologies that constitute the current state of the art in aircraft design. An “Advanced Rear End” component for the forthcoming generation of ultra-efficient aircraft might consist of a very compact rear fuselage and tail surfaces with planforms significantly different from those currently used in terms of aspect ratio, taper ratio and sweep angle.In this project, we aim at developing and validating an innovative, physics-based low-order method to predict the non-linear aerodynamic characteristics of lifting surfaces with controls whose geometry could significantly differ from the usual ones. The development and validation of the method relies on a high-resolution database scanning the extensive space of design parameters required in the call: sweep angle, aspect ratio, taper ratio, dihedral angle, shape of the leading edge and presence of ice. A recently validated approach, based on the most advanced techniques of uncertainty quantification, guarantees the reliability of the database of the aerodynamic characteristics that will drive the development of the method. The aerodynamic database will efficiently mix highly accurate experimental results with state-of-the-art, high-fidelity numerical simulations and lower fidelity simulations.The success of the project is guaranteed by the scientific quality and reliability of the partners in the consortium that have extensive experience in aerospace research projects, by state-of-the-art experimental facilities and aerodynamic-simulation open-source codes, and by a judicious use of subcontracting.


**Keywords:** Advanced Rear End, Low-oerder modelling, Uncertainty Quantifica
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Theory of Stein Spaces in Berkovich Geometry'.

assistant: **Innovation**

Complex Stein spaces may be thought of as analytic analogues of the affine schemes of algebraic geometry. They may be characterized in several manners: using convergence of holomorphic functions, topological properties or potential-theoretic properties, for instance. Especially useful for applications is the fact that their coherent cohomology vanishes. Despite the crucial importance of this theory in complex analytic geometry, its p-adic counterpart has hardly been sketched. In the setting of Berkovich geometry (one among the several notions of p-adic geometry), recent developments have enabled to get a fine understanding of the topology of the spaces (work of Berkovich and Hrushovski-Loeser) and to define the basic tools of potential theory (work of Baker-Rumely, Thuillier, Boucksom-Favre-Jonsson and Chambert-Loir-Ducros). The conditions for a comprehensive study of p-adic Stein spaces are now met; this will be our first goal. The theory will then be used to investigate envelopes of holomorphy and meromorphy. As an application, I plan to derive rationality criteria for power series over function fields. The second part of the project is devoted to the theory of Stein spaces for Berkovich spaces over rings of integers of number fields (where all the places appear on an equal footing). Those spaces have hardly been studied and only a very small part of the usual analytic machinery is available in this setting. Here, my main goal will consist in proving the basic and fundamental fact that relative polydisks are Stein spaces (in the cohomological sense). This will allow a deeper investigation of rings of convergent arithmetic power series (i.e. with integral coefficients) and will lead up to properties related to commutative algebra but also to the inverse Galois problem.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Reconciling gamebird hunting and biodiversity (REGHAB)'.

assistant: **Innovation**

Game bird hunting is an important socio-economic activity in Europe. It can provide benefits to biodiversity through e.g. the maintenance or management of habitats, but may also have negative implications for biodiversity, through e.g. the unsustainable use of resources or the illegal persecution of raptors in order to maximise game numbers. The latter is a key conflict for nature conservation in Europe. The aims of this proposal are: 1) to provide a global review on the costs and benefits of game bird hunting to biodiversity in different hunting regimes throughout Europe; 2) to review the conflicts between predator control and raptor conservation in Europe within the context of predator-prey interactions; 3) to address these conflicts in the context of the socio-economic value of hunting, and evaluate methods of reducing these conflicts; and, 4) to identify critical areas where knowledge is lacking, and propose future research priorities.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'World Year of Physics 2005: Activities in Europe' to be submitted under Sixth Framework.

assistant: **Abstract**

2005 will mark the 100 anniversary of A. Einstein's annus mirabilis, with his three seminal works on the photo-electric effect, the special theory of relativity, Brownian motion, which shaped physics theory and practice in the 20th century. On the eve of the 21st century, the European Physical Society, in Berlin during the 3rd World Congress of Physical Societies introduced a motion to declare 2005 as the World year of Physics that was unanimously adopted. Using Einstein's impact on physics and on society, a series of events marking the importance of his contributions, and the importance of physics to our cultural heritage, and technological and economic development are planned around the world in 2005. The present funding request federates 25 participants, and 33 projects designed to make WYP2005 a success in Europe.With the policy statements contained in the communication Towards a European Research Area, we are confronted with a need to increase awareness of the importance of scientific research in meeting future challenges in many key areas, such as energy production, environmental protection, health and economic development. Physics will play an important role in providing the necessary tools to develop the appropriate responses to these urgent questions. Physics research will also be a key to the development of other sciences, such as biology and medicines.Europe's ability attain the goals in the ERA document requires that it maintain and develop its scientific base.Policy makers, teachers, students and the general public need to be informed and interested in scientific development and its contributions to society. A new generation of scientists needs to be trained, and the importance of physics research needs to be highlighted.A bottom up approach has been taken
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Child health intervention interactions in low-income countries' (CHILIC) targeting Seventh Framework.

assistant: **Abstract**

Vitamin A supplementation (VAS) and vaccines are the most powerful tools to reduce child mortality in low-income countries. However, we may not use these interventions optimally because we disregard that the interventions may have immunomodulatory effects which differ for boys and girls and which may interact with the effects of other interventions. I have proposed the hypothesis that VAS and vaccines interact. This hypothesis is supported by randomised and observational studies showing that the combination of VAS and DTP may be harmful. I have furthermore proposed that VAS has sex-differential effects. VAS seems beneficial for boys but may not carry any benefits for girls. These findings challenge the current understanding that VAS and vaccines have only targeted effects and can be given together without considering interactions. This is of outmost importance for policy makers. The global trend is to combine health interventions for logistic reasons. My research suggests that this may not always be a good idea. Furthermore, the concept of sex-differential response to our common health interventions opens up for a completely new understanding of the immunology of the two sexes and may imply that we need to treat the two sexes differently in order to treat them optimally possibly also in high-income countries. In the present proposal I outline a series of inter-disciplinary epidemiological and immunological studies, which will serve to determine the overall and sex-differential effects of VAS and vaccines, the mechanisms behind these effects, and the basis for the immunological difference between boys and girls. If my hypotheses are true we can use the existing tools in a more optimal way to reduce child mortality without increasing costs. Thus, the results could lead to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Autonomic Service-Component Ensembles' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Future software-intensive systems, such as sensor networks, power grids, satellite and robot swarms, will generally exhibit a number of characteristic features:<br/>* Massive numbers of nodes, nodes with complex behavior, or complex interactions between nodes.* Operation in open and non-deterministic environments with variable network topology.* Need for adaptation, e.g., to changing environments and requirements.<br/>We call this future generation of software-intensive systems ensembles.  The potentially huge impact - both positive and negative - of ensembles means that we need to understand ways to reliably and predictably model, design, and program them.<br/>Although there is a lot of research in this area, so far no theoretically well-founded technique for building ensembles exists. The goal of the ASCENS project is to develop such a method and to demonstrate its feasibility in three important application domains: robot swarms, cloud computing and e-mobility.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Objective home-based EEG prediction of aMCI: Identification of a predictive electrophysiological model of cognitive function in amnesic mild cognitive impairment.' under Horizon 2020.

assistant: **Concept**

Dementia is an umbrella term for age-related brain disease, of which Alzheimer’s Disease (AD) is the most common. Around 5-7% of adults over 60 years suffer dementia worldwide, with approx. 8.7 m people in the EU. A frequent precursor of AD is amnestic mild cognitive impairment (aMCI), a clinical condition characterised by declines in memory skills. By predictingaMCI progression, health-care services will have new opportunities to deliver early interventions that could delay AD onset. This will ultimately promote functional independence in vulnerable adults and meet the societal challenge Health, Demographic Change and Wellbeing of Horizon 2020.Clinical outcomes of aMCI patients are influenced by the severity of cognitive (dys-) function. However, these deficits may occur at an  advanced stage of neurodegeneration. This fellowship aims to identify a predictive model of cognitive function based on brain activity measured with electro-encephalography (EEG). Previous studies suggest that the capacity to learn a new task (practice effects) can help classify a person into healthy, aMCI or AD. Also, cross-sectional studies using EEG have found differences between normal controls, aMCI and AD patients during rest and cognitive tasks. The behavioural and EEG evidence combined shows the potential of using behavioural practice and EEG measures to predict cognitive function. This potential will be investigated and exploited in this fellowship via advanced machine learning methods on a large EEGdata sample. This fellowship will take place in BrainWaveBank (BWB), an innovative company developing the largest database of EEG data in older adults along with cutting-edge analytics. This fellowship will allow the researcher to apply her experience on neural engineering and expand her kno
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Facilitating corporate-wide re-use though internet-based tools'.

assistant: **Innovation**

The SW applications for aerospace systems must satisfy strict quality constraints (in terms of reliability, safety and so on). This implies a high cost of design and development which needs to be compensated by introducing new costless working practices in order to be competitive on the market. The Project aims at:- Introducing a re-use oriented approach in the development of the software within the whole corporate and creating both the re-use culture", mandatory for proficient co-operation among companies, and the necessary organisational infrastructure.- Carrying out a complete Company-wide assessment of which software can be potentially re-usable.- Creating, distributing and maintaining a software catalogue of the re-usable software components identified exploiting the most updated telematic technologies.THE EXPERIMENTA Corporate Re-use Server will be installed, configured and made available to the many departments and companies of the corporate. The Server will be set-up using state-of-the-art and mature technologies and commercially available tools, capable of meeting the necessary strict security requirements, with the aim of supporting classification, storage, search and retrieval, which have been identified as key tasks in the re-use oriented software development process. The following tools/technologies will be used to set-up the server:- Internet, providing the underlying communication infrastructure to link the project teams involved in the Baseline Projects.- A Commercially available WWW Server (Netscape Commerce and Communication Server), i.e. a client-server tools providing the needed remote access facilities (storage and hyper textual navigation) and basic security and encryption mechanisms.- freeWAIS-sf, a public-domain indexing and search engine, specif
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Metal-Organic Cages for Catalysis Applications', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The formation of all carbon-based materials in nature starts with fixation and transformation of carbon dioxide (CO2) into useful chemical compounds. Such reactions are enabled by enzymes which often contain highly active metals as reaction centers that are deeply buried in a protein. In contrast, fine chemical production in industry is nowadays still mainly dependent on fossil fuels as carbon feedstock. Since fossil fuels are a limited resource there is an urgent need for alternative strategies. MOCCA (= Metal Organic Cages for Catalysis Applications) aims for the direct use of CO2 to functionalize olefins and produce higher carbon compounds. Principles from nature will be applied such as incorporation of metal catalysts inside a discrete cavity that allows specific substrate binding and activation. The process is divided into two steps: (1) CO2 reduction and (2) insertion of reaction products into the double bond of olefins, for example by hydroformylation. Both reactions are of high interest in chemical research and industry; several metal complexes have been reported as catalysts. Metal complexes are easily tunable via ligand design and molecular catalysts featuring active site mimics have been prepared. However, the current generation of these systems cannot compete with the efficiency of enzymes. Today it is clear that drastically simplified active site mimics do not fulfill all necessary conditions for keeping up with their natural paradigms, but also the outer shell plays an important role. Thus, the need for wrapping catalytic sites in a tunable chemical environment is evident. The nowadays available toolbox of design-driven supramolecular self-assembly allows the construction of such tailored environments, while investigation of encapsulated catalysts is still
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'The Political Culture of Post-imperial Intervention. The case of Spain and the South American republics of the Pacific (1833-1868).'.

assistant: **Objectives**

The project POST-EMPIRE will analyse the ideas and cultural representations that shaped the interventionist foreign policy deployed by the Spanish Monarchy in the republics of Chile, Peru and Ecuador during the Elizabethan period (1833-1868). I will reconstruct the doctrinal developments of pan-Hispanism, free trade imperialism, (anti)republicanism and navalism to understand how they structured the political culture of post-imperial interventionism, legitimising and guiding Spain's attempts to establish a sphere of influence in its former possessions. By studying a little-considered example of post-imperial interventionism, I aim to stimulate discussions at the academic and media levels that allow comparison with other analogous cases. POST-EMPIRE will achieve the following Research Objectives: RO.1: To explain the geopolitical imaginaries that gave rise to Spanish post-imperial interventionism. RO.2: Assess the weight that the examples of the British Empire, France and the United States had in the strategic culture of informal Spanish imperialism. RO. 3: To gain access to an interdisciplinary training experience that will allow me to enrich my knowledge as a historian of European-American relations with the perspectives of trans-Pacific historiography, political theory and socio-constructivist international relations theory. RO. 4: To contribute to elaborating an interdisciplinary theorisation of the dynamics that have characterised post-imperial conflicts throughout contemporary history. RO. 5: To enrich general social knowledge about the dynamics that govern post-imperial conflicts, seeking to raise awareness among public decision-makers and civil society of their importance for the Strategic Compass for the EU and European Security and foreign policy.


**Keywords:*