RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Photoelectrocatalytic device for SUN-driven CO2 conversion into green CHEMicals' (SunCoChem) under Horizon 2020.

assistant: **Objectives**

SunCoChem will have an important impact in reduction of the dependence of the European Chemical Industry (ECI) on carbon feedstock by producing a competitive and integrated solution enabling the carbon-netural production of high valuable chemicals from solar energy, H20 and CO2.SunCoChem will provide a solution based on a competitive tandem photoelectrocatalytic reactor (TPER) to efficiently produce oxo-products from CO2, water and sunlight. This will be achieved by process intensification coupling a sun-driven carbon dioxide reduction to CO/water oxidation to O2 with C-C bond carbonylation reaction catalysed by novel multifunctional hybrid photoelectrocatalysts (PEcats)SunCoChem is focused on the production of 3 main oxo-products of interest for three important chemical industries in Europe: i) Glycolic Acid, used as polymers building block and of interest to AVANTIUM CHEMICALS BV; ii) Valeraldheyde, a flavor ingredient of interest to and produced by DOW CHEMICALS; and iii) LimoxalTM a fragrance ingredient of interest to and produced by IFF.The TPER will be demonstrated at a TRL5 scale of 1m2 and validated by a set of 3 case studies corresponding to the 3 selected products, representing real chemical industry needs from the 3 mentioned industrial partners. The sustainable and efficient technology for oxo-products production will be demonstrated by addressing the recycling CO2 flue gas and by-products from Dow Chemicals and IFF, with an improved chemical energy conversion efficiency (≥10%) and CO2 emissions reduction (≥50%). The advantages of the SunCoChem technology in terms of social and environment impact will be analyzed with respect to conventional production routes of the same target products.Maximum impact will be ensured through the involvement of the mentioned
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Astronomy Fellowships in Italy' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Astrophysics research has typically an international dimension, since most of the projects require large collaborations. Many scientific projects are conducted by international teams. It is therefore essential that young researchers have the opportunity to work with teams in different countries.INAF – the Italian Institute for Astrophysics- intends to launch a programme of incoming mobility for researchers non-resident in Italy.  The AstroFIt programme here proposed will allow INAF  to set up for the first time such a programme.The fellowships will be carried out at INAF structures,  that include 19 Institutes broadly distributed in Italy and the Telescopio Nazionale Galileo (TNG) in the Canary Island.Two mobility types will be implemented: a) Incoming Mobility and b) Re-integration fellowships. Both types are of utmost importance for INAF, considering the so-called  “brain drain” phenomenon, not counterbalanced by an adequate attractiveness of Italian research centres for foreign scientists. Both the proposed types of fellowship try to invert this tendency.The limited number of fellowships foreseen is due to the fact that AstroFIt Programme is an integration of other international scientific collaborations, schemes and initiatives in which INAF is already involved. Nevertheless, Astrofit is important because unrelated to a single scientific programme but is devised to the strenghthening of the fellows capabilities in working in an environment different from the environment where initial training was achieved.The program will be 4-year long. Fourteen (14) fellowships will be offered, with two calls, each one including 3 Incoming mobility fellowships and 4 Re-integration fellowships. Every fellowship will last two years.  All the fellowships will be easily completed with
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'What can island isostasy tell us about hotspot dynamics?' (2007-2013) under Seventh Framework.

assistant: **Objectives**

Hotspots are enigmatic structures on Earth's surface that are not explained in the framework of plate tectonics. One of the characteristic features of oceanic hotspots is anomalously shallow seafloor, or hotspot swell, on which the volcanic islands associated with hotspots rest. The study of isostatic movements of oceanic volcanoes is a key discriminant among different theories of hotspot swell development. The Cape Verde islands, a hotspot archipelago located in a stationary plate environment, is a particularly good study area because the archipelago is stationary with respect to its melting source, it lies on the largest hotspot bathymetric swell on Earth, and because the archipelago is rich in uplift features. Quaternary wavecut surfaces and marine terraces are ubiquitous in the archipelago and can be found up to ~130 m asl, well above the relevant sea-level maxima. To date, these morphologies remain largely undated but our knowledge on their age is crucial to resolve the mechanisms behind hotspot dynamics. If they are synchronous on different islands they reflect a regional pulse in hotspot swell growth that has not been reported previously. If, conversely, they are not synchronous between islands, they require local uplift mechanisms (e.g. basal intrusions), also not previously documented. We propose an innovative multi-disciplinary approach to date the Quaternary uplift features of Cape Verde using state-of-the-art multi-nuclide surface exposure dating of wavecut surfaces in combination with U/Th Disequilibrium geochronology of marine terraces. The information will provide an uplift chronology that will be used to test competing hotspot swell development models and hotspot theories
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Low power spintronics wireless autonomous node (SWAN) integrated circuits developed via spintronics technology accelerator platform'.

assistant: **Innovation**

One of the central keystones of the digital transformation of society is the Internet of Things (IoT) paradigm, however recent focus has turned to the energy consumption of the billions of IoT sensor nodes. In order for the realisation of a ‘Green IoT’, low-power sensor nodes are essential, to extend node lifetime, reduce carbon footprint and reduce costs. Spintronics is an emerging technology which has been demonstrated for several key functionalities associated with wireless sensor networks, including sensing, energy harvesting, communication, memories and novel processing paradigms.In SWAN-on-chip a spintronics wireless autonomous node (SWAN) is proposed for low-power edge computing. Three homogeneously CMOS integrated spin-chip modules will be developed and benchmarked in the context of low power IoT nodes (namely magnetic field sensor, wireless power transfer, wake-up receiver) (Objective 1), and these spin-chip modules will be brought together into a SWAN prototype functional demonstrator capable of real world data capture and used for specific end user test cases (i.e. electric vehicles and smart metering) (Objective 2).As well as developing individual spin-chips, a system-on-chip style SWAN-on-chip concept will be validated, with different spintronic functionalities being interconnected via CMOS, either by using multi-functional spintronic stacks or masking techniques to allow multiple spintronics technologies to be processed on a single CMOS wafer (Objective 3).In addition, the SWAN-on-chip concept will be used to validate the ‘spintronics technology accelerator’ platform, where the spintronics equivalent circuit models (Spin-EC) and spintronics multi-project wafer (Spin-MPW) will create a European-level pathway for the fabrication of monolithically integrated
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Kinetic Investigation of Simulated Magnetosheath Electron Trajectories and Spacecraft Potential Accumulation RisK'.

assistant: **Objectives**

Satellites in space are subjected to charged particles in the ambient environment. Specifically, the fast-moving electrons of the space plasma can rapidly accumulate on satellite surfaces. These surfaces may then suddenly discharge in electrical arcs that damage the onboard electronics, which may even result in total loss of the spacecraft. The project KISMET-SPARK will be the first dedicated study of surface charging during rare but impactful events known as ""Geosynchronous Magnetopause Crossings"" (GMCs). During a GMC, the solar wind compresses the Earth's magnetic field. This ends up placing satellites in Geosynchronous Earth Orbit (GEO) within a region known as the magnetosheath, where the ambient electron fluxes and resulting surface charging can be intense.In KISMET-SPARK, the Applicant Konstantinos Horaites will address the kinetic physics of electrons in Earth's magnetosheath and their space weather impacts. In two Work Packages, he will 1) describe the processes that shape the energized ""flat-top"" electron velocity distribution (eVDF), and 2) evaluate how these electrons contribute to the costly GEO satellite failures that are correlated with GMCs. The project will be supervised by Daniel Verscharen, who is an Associate Professor at the Host institution, the University of College London's Mullard Space Science Laboratory. The Applicant will simulate the magnetosheath environment using state-of-the-art kinetic ""eVlasiator"" simulations of Earth's magnetosheath. He will employ the Supervisor's ""ALPS"" code to assess the kinetic stability of the eVDF, which will explain the origin of the flat-top population. This project will combine the Applicant's experience with simulations together with the Supervisor's knowledge of space-plasma instabilities, to answer l
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Targeting Inflammation and Neurogenesis using cannabinoids to delay the onset of Alzheimer’s disease' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Alzheimer’s disease (AD) is the most common neurodegenerative disease and accounts for the majority of diagnosed dementia after age 60. It is estimated to currently affect between 20 and 30 million people worldwide, with 4 millions in the U.S. alone. As life expectancy increases in developed countries, the prevalence of AD, and its burden on healthcare, is very likely to increase dramatically in the next few decades. While waiting for a cure for AD as its prevalence will increase drastically over the years, a medication approach that would delay the onset of the disease would have a major impact of the disease incidence and prevalence, and thus on its burden on the economy of industrialized countries. Our main hypothesis is that excessive inflammatory processes (and its subsequent effect on protein function like MMPs and neurogenesis) are part of the early events triggering deleterious processes observed in AD later on. We do hypothesize that a diminution (but not complete inhibition) of those inflammatory processes, notably using the EC system, could benefit brain functions (neurogenesis, memory processes, APP processing to non-toxic amyloid forms…) and thus decrease the incidence of AD by delaying/reducing the appearance of hallmarks of AD. This proposal will then clarify the possible influence in vivo of chronic inflammation and its pharmacological modulation (and inflammatory-related proteases as MMPS), as well as neurogenic processes and behavior in a well-established transgenic model of AD. This study will thus provide valuable mechanistic information underlying the possible modulating role of the inflammation, MMPs and EC in the development of the AD pathology. Overall, those experiments could pave the way to a possible active treatment aiming at lowering the inc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Optical Microscope for Imaging High-Speed Precision Surface Processes'.

assistant: **Objectives**

SURFLIGHT is at the forefront of optical microscopy innovation, aiming to bring an exceptional microscope to the market. We have developed a high-resolution microscope (up to 2 nm) capable of monitoring ultrafast surface processes (s-scale) on non-transparent materials under real operational conditions. This innovation holds promise for industries like semiconductors, batteries, and green energy, where it is critical to visualize surface phenomena label-free and in real-time. SURFLIGHT's microscope excels in identifying active sites on surfaces and nanomaterials, essential for catalytic reactions or solar energy conversion. This technology streamlines catalysis R&D by offering real-time visualizations, cutting costs, and optimizing catalyst utilization. Moreover, it minimizes the need for repetitive tests, conserving time and resources, while enhancing catalyst lifespans and reducing replacements through real-time monitoring of catalyst degradation under real-world conditions. Most importantly, it safeguards against large-scale process failures, resulting in substantial cost savings in materials and reduced downtime. A thorough market analysis within SURFLIGHT will allow us to step up our dialogue with academic as well as industrial partners and thoroughly characterize the industrys demands and needs for the microscope. This will allow us to undertake a final optimization of the microscope once identified the initial targeted customer sector. This ERC PoC will be central for pursuing these goals. We envision SURFLIGHT in the market rapidly and attracting commercial interest from a wide range of industrial sectors.


**Keywords:** Microscopy, Surface Science, Energy, Optics
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Probing CD28 as checkpoint for T cell co-stimulation in cancer and infection' in the context of a Horizon 2020 call.

assistant: **Objectives**

Regulation of T cells has been a cornerstone in the development of therapeutics for fighting a wide plethora of pathologies, including cancer, chronic infections and disease. The mechanisms governing activation or repression of T cells depend on several receptors which provide “second signals” following the initial interaction with APCs presenting MHC complexes. Among these receptors, CD28 constitutes the main interest for this project. Its role as co-stimulator of T cell activity is known for so long. However, the particular mechanisms underlying its effective interaction with its cognate ligands (CD80/CD86) remain unclear yet. In particular, the present project is aimed at exploring the possible role of sialic acid in regulation of CD28 co-stimulatory activity (via inhibition), which could provide a novel explanation for the so-called “neuraminidase effect” described for decades. This effect leads to enhanced antigen-mediated T cell activation when sialic acids are enzymatically removed, but its origin is uncertain. Additionally, the structural basis for CD28 regulation will be explored, putting an special emphasis on its exploitation for the design of molecular platforms which may serve for reactivation of exhausted T cells in tumor models. The proposed project will be jointly undertaken by two renowned groups with large and solid experience in the field of glycomics, at CIC bioGUNE (J. Jiménez-Barbero) and Scripps (J.C. Paulson). The applicant, under their guidance, will develop the project from a very wide and cross-disciplinar perspective, covering all unknown aspects related to CD28 so far as well as proposing a novel methodology to translate this knowledge into valuable goods for society. The success of the project will likewise have a remarkable impact in the f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Semi-Classical Analysis and Partial Differential Equations' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Semi-classical  analysis  started to be developed about 50 years ago by the works of Sato and Hormander on micro-local analysis.Nowadays, it has reached great achievement with many applications to different topics in analysis including spectral theory, scattering theory, control theory, and some aspects in non linear equations, by the use of dispersive estimates and paraproduct techniques .The objective of our proposal is to develop new tools and applications in two directions : boundary value problems and connections between probability and semi-classical analysis. We expect to solve  basic remaining open problems in the analysis of boundary problems, and to make  contributions to develop new links between probability and analysis of partial differential equations.We will focus on four topics :- 1) Dispersive and Strichartz estimates for wave or Schrödinger equations in domains. Applications to the Cauchy problem for non linear waves in domains.- 2) Theoretical analysis of the optimal control operator in control theory.- 3) Analysis of  Markov Chain Monte Carlo algorithm of Metropolis type via PDE's tools.- 4) Applications of  probabilistic tools to  the analysis of  PDE.Topics 1) and 2) are strongly connected to progress in the analysis of boundary value problems.Topic 3) involves a generalization of the classical pseudo-differential calculus. The purpose of topic 4) is to develop a new field of research for deterministic PDE's (and therefore is not in the area of stochastic PDE's).All topics involve geometric analysis in the phase space.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Development of a virtual process planning system'.

assistant: **Innovation**

DEVELOPMENT OF A VIRTUAL PROCESS PLANNING SYSTEM .There more than 5500 manufacturers of special purpose plant, covering virtually all industrial sectors and including equipment for applications as diverse as food & drink production, plastics processing, assembly and work placeventilation. Whist some examples are huge in cost and size, such as oil and petro-chemical plant, more than 95% of special purpose equipment sold in Europe is below the 100kECU price mark. In this market area SMEs dominate, and account for almost 70% of the total population of suppliers. Many of the key market segments for special purpose plant are represented by the five SME end users in the core group. Because of their relatively small size they tend to be more flexible in offering bespoke equipment solutions than European LEs However, they are often disadvantaged when competing with companies from lower labour base economies such as those in the Pacific Rim. These competitors are often LEs, as they require fairly powerful sales and maintenance support structures to overcome the disadvantage of the large geographic distance between customer and manufacturer. In response, European SMEs concentrate on differentiating their offering by providing higher added value through building a partnership approach to the equipment solution they hope to supply In this manner they can also help clients to adopt lean manufacturing techniques and accommodate increasingly frequent reconfiguration of manufacturing processes using computer aided simulation techniques. The key to this is better communication of solution concepts and plant configuration / reconfiguration, enabling them to work, closely with client, as an integrated team, initially when selling the plant and in the longer term when helping the customer