RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'An integrated framework for climate-resilient earthen cultural heritage.' (INTERRA) under Horizon Europe.

assistant: **Objectives**

Earthen cultural heritage (ECH) sites, representing millennia of construction traditions, are increasingly vulnerable to the adverse impacts of climate change, including extreme weather events and environmental degradation. Without addressing the growing vulnerabilities of these structures to environmental stressors, the risk of losing not only their material essence but also their cultural resonance increases. Despite recent advances in conservation science, current methods lack the predictive capabilities necessary to address climate-specific threats to ECH. The INTERRA project (An Integrated Framework for Climate-Resilient Earthen Cultural Heritage) addresses this gap by combining hygro-thermo-mechanical (HTM) monitoring with Historical Building Information Modelling (HBIM) to create a comprehensive framework for assessing and mitigating climate risks. The project will be hosted during the outgoing phase at Université de Sherbrooke (Canada), with a secondment at ETH Zürich (Switzerland), and return phase at University of Minho (Portugal). Through collaboration with these three world-class hosting institutions, the researcher will acquire advanced skills in multiphysics modelling and conservation technologies. The development of innovative tools through INTERRA will provide real-time data on the structural behaviour of earthen buildings and establish benchmarks for future conservation efforts. This methodology aims to preserve both the physical integrity and the cultural significance of ECH structures, extending their lifespan, reducing long-term maintenance costs, and ensuring the continuity of these cultural practices for future generations. This approach will foster sustainable conservation actions, enhancing the resilience of ECH in the face of increasing environm
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'The intelligent system for net shape forming of sheet metal products' in the context of a Fifth Framework call.

assistant: **Objectives**

The present project concerns compensation of the shape and size of tools for 3D sheet metal forming processes considering the residual stresses and spring back of the material after forming as well as after trimming, punching and parting of the draw pieces. Tool compensation method using the FEM simulation incorporating into professional programmes will make it possible to obtain products with high accuracy, which is essential in assembling of complex products like car body. The benefit of practical application of the tool shape compensations method is significant. The important problem of the dimensional quality of draw pieces will be solved, which could be done so far only by expensive experiments in technical scale. Wide known scientists and design engineers from universities, research institute and industry create the consortium. The elaborated system for net shape forming of sheet metal products will bring economical and technical advantages.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Carbon nanotube structures as innovative electrode materials for more efficient energy storage devices' (2007-2013).

assistant: **Innovation**

Efficient capture, storage, and controlled release of energy are major global challenges for the twenty-first century. Dramatic improvement in the performance of energy storage & conversion devices is needed to meet future energy demands of our society, mainly in electrical propulsion (full electric vehicle) and to overcome the inevitable future shortage in fossil fuels, especially in gasoline. By combining Professor Aurbach (Bar Ilan University) expertise of electrochemistry, especially of Li and Mg, with Dr. Gilbert Nessim (MIT) capabilities in synthesizing dense arrays of crystalline carbon nanotubes (CNTs) on metallic layers, we propose to investigate the development of more efficient batteries that use composite metal-CNTs as electrodes. The main novelty of our approach is to use functionalized carbon structures on various nanotube electrode materials to improve ion insertion and storage, safety, and performance of Li ion based batteries in ionic liquid and in electrolyte solution with wide electrochemical window. The technical plan includes the investigation of multiple electrode materials and geometries upon which CNTs will be grown and functionalized to optimize electrode performance and cycling. Additional aspects of this project include applying the techniques and materials developed to lead acid batteries and to design more efficient supercapacitors. Extensive collaboration with MIT and with other academic and industrial institutions in Europe and the USA is a key aspect of this multi-disciplinary project. The goal of the project is to reintegrate Dr. Nessim at Bar Ilan as a faculty in the department of chemistry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Electromagnetic Interactions with Nucleons and Nuclei' in the context of a Fifth Framework call.

assistant: **Objectives**

Electromagnetic Interactions with Nucleons and Nuclei are an important tool to study the structure and the strong interaction of extended hadronic systems. It is the aim of the proposed conference series to provide a forum for a community which originally was separated into three groups:- nuclear physicists, who traditionally were used to argue in terms of nucleons and mesons as basic building blocks of matter and meson exchange as origin of the nuclear force;- 'medium energy' particle physicists, who study mainly ground state properties of hadrons and the spectrum of their excited states in terms of 'constituent' quarks, and;- 'high energy' particle physicists who deal with quark and gluon degrees of freedom in the regime where the strong force can be described perturbatively by the underlying field theory -Quantum Chromo Dynamics (QCD).The ultimate goal of today's hadronic physics with electromagnetic probes is to understand the strong interaction in the transition region where quarks and gluons become 'confined' into the observed subnuclear particles and where perturbative methods no longer work. This calls for a coherent effort and essentially a merging of the three groups and also tight collaborations between experimentalists and theorists.A strong and active community is performing experiments at various European Facilities as well as leading collaborations at Facilities in North America. Many second-generation experiments have been started which in the coming years will produce high statistics data of unprecedented quality. Also on the theoretical side there are recent promising developments which are hoped to help clarifying the physics of confinement.The present programmes at the different facilities cover at least the next five years, upgrades are being discus
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Power Conversion Units for LifeRCraft demonstrator' (POCOL) under Horizon 2020.

assistant: **Objectives**

The growth of Power Electronics has been driven by the demand for more electrical solutions in a very diverse range of application sectors, including transport electrification, energy generation, transmission and distribution, consumer electronics and lighting, industrial motor drives. This range of applications has brought increasing demands on the performance, reliability and cost of power electronics and the associated power conversion techniques, leading to a rapid and dynamic improvement in a range of essential technologies.In this context, two leading institutions in the field of power electronics, Techniques et Fabrications Electroniques (TFE) and the University of Nottingham (UNOTT) are combining their forces in order to propose a project (POCOL) that will enable a step change in the development of high specification power converters for modern aircraft application such as for the lifeRcraft helicopter.The two partners of the project will be organized as to get the best of their specificity. Being a University well known for its strong research activity allows UNOTT to lead the project at the beginning for the three first work packages, setting up the bases of the design. As an equipment designer and manufacturer working in the aeronautic area, TFE will be the leader of the rest of the project and will be able to propose an industrialization of the product made under the POCOL project.TFE and UNOTT will work together to:•Develop models and design the required power converter and inverter to meet the functional and operational performance and reliability requirements set out in the CfP. •Manufacture B1 prototypes that meet the design criteria up to TRL5•Test the B1 demonstrators under relevant environmental and operational conditions•Re-iterate knowledge gained f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Workshop estuarine systems on the mediterranean and black sea regions"' under Fifth Framework.

assistant: **Concept**

Many R&D projects are being carried out worldwide and within the European Union on the long-term stability of vitrified nuclear waste.The objectives of this topical workshop are to(1) discuss the actual status of the understanding of the behaviour of nuclear waste glasses in their anticipated disposal environment,(2) reach a consensus on the issues proposed in the workshop, and(3) improve the focus of the future projects on nuclear waste glass. A topical workshop bringing together the international experts is an excellent approach for achieving these objectives. The results of the workshop should be an enhanced consensus, a better focus in future programmes, and Proceedings with all oral papers and poster presentations.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Process of manufacturing brake linings (but not limited to) by the use of ultrasonic energy input' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Compaction processes for composite materials are widely used in the industry for the production of highly filled composites. Moulding of e.g. friction materials using heat and pressure in the traditional manner becomes increasingly inefficient. The energy used in the process is excessive. The above mentioned problems could be solved by using ultrasonic energy, leading the energy direct into the centre of the composite materials. In conventional processes the energy dissipated in heating the mould is grossly excessive as heavy press tools, supported on press platens of considerable mass, have to be maintained at temperature which can enable the composite moulding compound to flow and fill the mould. Subsequently process control is only possible within relatively large tolerances. This is a problem to maintain constant product quality. Waste, resulting of bad products produced, is a consequence. By using the new technology (compacting powderous materials by means of energy input via ultrasonics), big savings in production costs (typically for large products like e.g. heavy duty drum brake linings- could be reduced down to 50% or even more). The main reasons for the savings can be found in material savings due to exact controllable process allowing for having no rejects and also in the fact that equipment costs for manufacturing are cheaper, as it can be built in light duty version. Another big saving can be found in the fact, that by the 'moulding in-shape' process, many operations after press cure can be eliminated compared to existing technologies. All over this new technology opens a wide range of applications, if the equipment can be built for industrial usage. Typical examples are friction pads, heat shields, electrical insulations and connectors, machinery parts and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Miniaturised optically accessible bioreactor for drug discovery and biological research' (MOAB) targeting Horizon 2020.

assistant: **Abstract**

The problem that we address is that the pharmaceutical companies do not develop radically new drugs anymore, because the development process lasts ten years and costs around one billion euro. Development of a new drug is subjected to regulatory approvals following three demonstrations: lab discovery in vitro, animal testing in vivo and clinical trial on patients. This process has 99.9% overall failure, of which 96.4% because the drug efficacy measured in vitro is not confirmed in animals. In fact, the most widespread technology used to test therapeutic agents in vitro, a flat culture dish in which single cell populations are cultured and the drug to be tested is added to the culture, is obsolete. In many pathologies such as cancer and neurodegeneration, in vivo response to drugs is based on complex interactions, occurring in three-dimensions (3D) between several cell populations. To solve this problem, in the context of an ERC consolidator grant (CoG) that I currently lead, I integrated a novel nano-patterned 3D substrate for stem cell culture, called the “nichoid”, into an existing miniaturised optically accessible bioreactor (MOAB). The MOAB allows to culture 3D organoids of few millimetres in size, under continuous perfusion of the culture medium, infusion of the drug to be tested and diagnostics of cell response both in real time and also post-cultivation. Both the original inventions (the nichoid and the MOAB) are covered by Italian patents originated in the frame of the CoG project and already extended as PCT. The goal of this PoC proposal is to perform a technical and commercial feasibility to move to  the market the MOAB device integrating the nichoid-patterned substrate. I will characterize the fluid-dynamics of the bioreactor chamber that has been modified to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'A new vision on nanocatalysts' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

In recent years it has been recognized that small metal nanoparticles hold the promise that their catalytic properties may be completely different from those of their bulk analogs or their monometallic complexes. Entirely new chemical conversions may be expected because of their shape and thermodynamic properties. So far, this promise has not led to important breakthroughs, as most findings can be categorized, mostly, as typical of homogeneous catalysis, or mimics of heterogeneous catalysts, especially hydrogenation. Nanoparticles need stabilizating reagents; polymers, dendrimers, ionic liquids, detergents, solid surfaces, and small ligands, have been discovered and used by trial and error. In this project we propose the use of concave, large organic molecules that will be developed and used to stabilize small nanoparticles by covering part of the vertices and apices, thereby controlling the size and the shape, leaving edges next to the molecular wings and uncovered surface available for interactions leading to catalysis. The controlling wings contain two or three strongly binding phosphines to prevent dissociation of the controlling agent and to modify, simultaneously the electronic properties of part of the metal atoms. The organic platforms have the advantage that additional groups can be connected to them which can serve as chiral modifiers, as recognition sites for larger molecules, as additional organic catalysts, or as ligands to hold a homogeneous co-catalyst. Three high-risk reactions will be investigated, (enantio)selective hydrogenation of aromatics, conversion of glycerol to high added value products and the selective conversion of syn gas by using devices derived from homogeneous and supramolecular catalysis.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Genetic correction of glycogen debranching enzyme deficiency in Glycogen Storage disease III: a proof of concept study'.

assistant: **Objectives**

Glycogen storage disease III (GSD III) is a rare (1:100,000) autosomal recessive disorder that results from the deficiency of the glycogen debranching enzyme (GDE). The major cause of morbidity is associated with the muscle accumulation of glycogen, which leads to progressive myopathy. A dietary treatment with frequent meals high in carbohydrates, slows the progression of the pathology that is however inevitable. There is no cure for GSD III, the recent development of a mouse model lacking GDE activity, which recapitulates the human condition, represents a unique opportunity to develop and test novel therapies for the disease. Here, we propose to perform a proof-of-concept study of an adeno-associated virus (AAV) vector-mediated gene therapy for the treatment of GSD III. AAV gene therapy has been successfully used for the correction of several genetic diseases in animal models and humans. One of the main limitations of AAV vectors is that they cannot package vector genomes significantly larger than 5kb. Due to the length of the sequence of the GDE enzyme (4596 bp), we engineered a dual-vector system with a recombinogenic sequence to drive reconstitution of the full-length GDE sequence. In alternative to this strategy, we engineered also a truncated GDE that can fit in a single AAV. Because GSD III is both a liver and muscle diseases, and because the liver is involved in glycogen metabolism and, ultimately, in the supply of glucose to the muscle, we will test two main therapeutic strategies to treat GSD III, consisting of constitutive or liver-specific expression of the transgene. The rescue of the GDE enzyme deficiency will be carried out in vivo in a GDE KO mouse, and in vitro in human iPS cells-derived hepatocytes and myocites. We will generate fibroblast-derived iPS
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Organising, Classifying, Evangelising. Production and Circulation of Knowledge in Rural and Independent Catholic Action (Belgium-France, 1931-1986)' (2021-2027).

assistant: **Concept**

The ORa.CL.E project aims to shed light on overlooked producers of knowledge about society  specialised Catholic Action (CA)  and explore the hypothesis of the circulation of religious militant-based knowledge to academic sociology. Social classifications were the essence of the project of the so-called specialised CA movements, which proposed selective pastoral approaches according to life milieus. This segmentation was not simply a strategy imposed by the episcopates from above, but was a continuous process of differentiation and identification by class and by gender at all levels. Assuming that CA specific forms of organisation produced social categories and knowledge that might have circulated to the field of academic sociology, ORa.CL.E offers an innovative reinterpretation of the history of specialised Catholic Action, from a sociology of science perspective. The project transcends the traditional monographic historical studies of CA, by developing an original comparative methodology based on the analysis of five understudied CA movements for adults from rural and independent backgrounds in France and Belgium from 1931 to 1986. ORa.CL.E provides new insight on the role of religion in social distinction and offers new perspective on the relationship between science, religion and civil society. Such a renewal is essential in the current European context, where experts and the media often present religious experience as an individual phenomenon, autonomous from social structures. In consultation with actors from present-day CA education movements, the project will provide tools to better understand the circulations between religious ground knowledge and academic knowledge, which will help in the future to make better use of the former and improve the social relevance