RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'SYstem for Digitization and Diagnosis in ART Applications' (SYDDARTA) under Seventh Framework.

assistant: **Objectives**

Cultural heritage monitoring comprehends a sum of technologies, protocols and studies which need to be modernized and automated to reduce costs and process time. Current spectroscopy permits the study and characterisation of the surface of artworks by the inspection of specific spectral bands, by means of different techniques. As a consequence, the sets of results are often difficult or slow to link, compare or process in order to generate global information about the piece-in-study. In this way, a set of analysis processes must be performed over the artwork, involving piece moving, manipulation, transportation, etc, and therefore putting the artwork at risk of deterioration. The main target of SYDDARTA is to develop a pre-industrial prototype for diagnosing the deterioration on movable assets by the acquisition of 3D-hyperspectral imaging through scanning non-destructive techniques. Such images contain spectroscopic information of the piece to be analysed in different bands of the spectrum, giving chemical composition information of the different materials and layers in the actual 3D surface by means of a very narrow screening bandwidth and the use of volumetric digitisation. These analyses are carried out combining mapping, spectroscopic and image processing techniques, based on tunable filters and customised light sources. The expected prototype will be a new portable type of equipment to use in the preventive conservation and monitoring of movable cultural assets and will provide enormous data sets by non-destructive characterisation techniques. Moreover, the equipment will make use a specific database of materials and pigments monitoring that will be exploited as well. The merging of the technologies involved will be suitable for fast authentication and traceabilit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'SME-led antibody glyco-engineering' (SAGE).

assistant: **Innovation**

The aim of the SAGE project is to establish an improved plant production platform for pharmaceutical glycoproteins. Plant systems are inexpensive, scalable and safe, providing unique advantages for the production of pharmaceutical proteins, including therapeutic antibodies that are normally too expensive to produce through conventional means. This applies particularly to antibodies that are required in large amounts for use as diagnostics or in the treatment of certain types of cancer. However, the glycan structures added by plants are different to those found in humans, and the glycoform of an antibody is strongly influenced by the plant species, tissue, cell type and age. Using different plant-based expression systems and mammalian cells as a control, we intend to produce a therapeutic antibody that recognizes the well-characterized carcinoembryonic antigen (CEA). The antibody will thus be produced as a panel of different glycoforms, which we will test these systematically for stability, efficacy (e.g. in Fc-receptor binding assays, tumour cell binding assays and tumour grafting) and pharmacokinetic properties such as serum half life and ADCC (antibody-dependent cellular cytotoxicity). These results will be exploited to develop safer and more active glycoform varieties for therapeutic applications. The SAGE project will be carried out by an international consortium of laboratories including one SME, four research organizations and two companies (Bayer BioScience, which is not requesting EU funding, and Icon Genetics). These participants are recognized as leaders in plant-based production technology and immunology, so approximately equal weighting will be given to the plant genetics and antibody characterization work within the project. The consortium is strengthened b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Robotic Automation Modules for Production' (RAMPup).

assistant: **Concept**

RAMPup aims to improve European SME production competitiveness by effectively decreasing the integration effort needed for automating small production lines. A framework and infrastructure for modular industrial automation systems will be developed and applied to eight use-cases from four European end users, carefully selected to require a broad range of processes. Technologies for automating these processes exist, but are too inflexible and expensive for the business case for automation to be viable, certainly in SME contexts. Four demonstrators will be realized and brought to TRL7 proving their performance in real operational environments at end user sites.The methodology involves creating manufacturer-independent process modules which are self-contained: hardware, software and process functionality; wrapped to be “plug-n-play” with all other modules in the set and with the framework platform. We anticipate that many modules will be based on existing technologies, completed and wrapped to become RAMPup modules. A repository of process modules at this level, accepted as usable by SIs, will greatly reduce the customization needed for new automation installations, thus reducing the cost to end-users. Modularisation also allows physical reconfiguration of the workcell and re-use of component modules across very different product variants.Beyond the technical realization of the modular automation framework, RAMPup aims to open a new market allowing developers of automation solutions to deploy, distribute and commercialize their products. RAMPup will demonstrate the business perspectives within the project and thus convince module developers and system integrators to enter the new market.The ambition in RAMPup is thus not only to create eight functioning robot workcells at
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Symmetry and shape' in the context of a Sixth Framework call.

assistant: **Objectives**

The increasingly demanding challenges in our society and environment constantly require the development of new innovative ideas. These ideas often originate from mathematical models of phenomena in natural and life sciences, in medicine and business, in technology and engineering, in manufacturing and design, and in other areas. Many of these models lead to geometric structures describing the phenomena precisely or, in most cases, approximately. Innovation and scientific development depends upon a thorough understanding of these geometric structures.The major aim of this research project is to investigate geometric structures from the viewpoint of their symmetries, and to characterize them by some distinguished features. More precisely, we plan to investigate the shape of submanifolds of spaces equipped with a Riemannian structure that are invariant under a subgroup of the isometry group of the space. A particular objective is to study cohomogeneity one actions on symmetric spaces and characterize their orbits by geometric data. This will be achieved by using techniques recently developed by the host group and by implementing a computer program of symbolic calculus, a matter in which the applicant is experienced.This proposal suits the objectives of this action: it promotes interdisciplinary relations (cohomogeneity one actions have successfully been used for the construction and investigation of special structures which have substantial interest in physics; we use programming techniques to handle symbolic calculations), reinforces international relations (the candidate comes from a less-favoured region and is hosted by a group with many international research collaborators) and improves the expertise of the applicant ensuring a position of professional maturity (the ap
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Characterising field emergence in cultivated herbaceous vegetation' (2002-2006) targeting Sixth Framework.

assistant: **Abstract**

Over the past 10 years, multi-disciplinary research in the Department of Landscape, University of Sheffield, has pioneered the establishment of decorative herbaceous vegetation in urban parks and greenspace by sowing seed in-situ. This eliminates the need for heated glasshouses, fertilisers, pesticides, irrigation water, plastic pots, peat, plus the energy consumed in the transportation of these materials associated with vegetation established by planting container grown nursery stock.The resulting vegetation is taxonomically and spatially complex, provides a rich habitat for wildlife and is highly attractive to urban people. For these reasons it is desirable to establish more urban vegetation by sowing, but to do so, landscape architects must be confident that this emerging technology works and is reliable in terms of establishing the target species at appropriate densities. The proposed TOK will lead to the commercialization of these techniques through a partnership with an SME, Jelitto Seeds, who is the major producer and supplier of seeds of these species in Europe.To achieve this successful commercialization a number of scientific questions must first be resolved;- develop an easily undertaken, standardized screening technique to predict field emergence of non-agricultural herbaceous plants,- characterize the field emergence of 1000 species of the herbaceous taxa sold by Jelitto,- Test the reliability of the screening process in practice through field scale sowing experiments using formulated seed mix products.The project involves 2 fellows; a seed industry person based at University of Sheffield, and the other a germination ecologist post doc based at Jelitto Seeds. The outcome of the research and training will be communicated to other researchers in the field and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Using milling balls as catalysts –  Understanding the novel concept of direct mechanocatalysis' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

I propose a novel concept of catalysis neither utilizing light, thermal heating nor an electric potential as in conventional catalysis, but simply mechanical energy. In this mechanochemical approach, mechanical energy is provided by the collision of milling balls inside a ball mill. The catalyst is neither dissolved (as in homogenous catalysis), nor a powder or bed of shaped bodies (as in heterogeneous catalysis), but the milling ball itself. I want to study how even in the absence of any solvent, solid reactants can be brought into reactions mechanocatalytically - only using milling balls that refresh their catalytically active surface constantly during their continuous collisions. I want to showcase this concept for a type of reactions that is commonly in the hand of homogeneous catalysis  C-C-cross coupling reactions catalysed by Pd, Cu or Ni. Understanding this novel concept involves 1) identifying reactions and reactants that can be applied to direct mechanocatalysis, 2) elaborating how mechanochemical reaction parameters such as milling speed, ball size and ball roughness replace common reaction parameters such as concentration or type of solvent and 3) elucidating the underlying mechanisms by employing in situ characterization techniques that allow for the monitoring of the reaction directly inside the moving milling vessels. I believe direct mechanocatalysis to be ground-breaking as it involves reactants that can hardly be brought into reaction via conventional approaches because of low solubility or limited stability in solution. The proposed solid-state approach will be fundamentally different from the conventional solution-based procedures, and I foresee new reactions to be possible. This approach is highly sustainable as it makes the use of any solvent obsol
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Study of the therapeutic potential of an Akkermansia muciniphila-based products in subjects with an increased cardio-metabolic risk.' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Overweight and obesity have reached worldwide epidemic level. Both overweight and obesity are characterized by comorbidities such as cardio-metabolic risk factors (i.e., insulin resistance, type 2 diabetes, hypertension, dyslipidemia, low-grade inflammation) representing a major public health problem. Therefore, it is urgent to find a therapeutic solution to target all these metabolic disorders.Among the environmental factors able to influence the individual susceptibility to gain weight and to develop metabolic disorders associated with obesity, we have contributed to the demonstration that gut bacteria (i.e, gut microbiota) influence host metabolism. We recently discovered a putative interesting microbial candidate, namely Akkermansia muciniphila. More exactly, we found that the administration of Akkermansia muciniphila reduced body weight gain, fat mass gain, glycemia, cholesterolemia and inflammatory markers in diet-induced obese mice. Moreover, in overweight/obese patients subjected to a calorie restriction diet, the higher abundance of Akkermansia muciniphila was associated with a better cardio-metabolic status. These observations suggested that the administration of Akkermansia muciniphila in overweight or obese people could be a very interesting therapeutic solution. Currently, no human study have investigated the beneficial effects of Akkermansia muciniphila administration on obesity and metabolic disorders. Thus, the main objective of this ERC POC project “Microbes4U” is to get the proof of concept in humans of the safety and efficacy of Akkermansia muciniphila administration in the treatment of overweight, obesity and metabolic disorders associated such as insulin resistance, type-2 diabetes and dyslipidemia.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Design HEALS: Investigating Design Guidelines for Healthy Assisted Living Settings' (2007-2013).

assistant: **Concept**

Recent European Commission (2008) report on “Long-term care in the European Union” announced that demands for quality and quantity of long-term care services bound to rise. As current models for healthy ageing define institutional care as the last resort, assisted living settings fill a big gap between home and institutions. Varying in scale and design, the overall concept of assisted living facilities is to provide home-like physical environment and social support for those who require help in performing their activities of daily living. The aim of this research is to study the link between environmental qualities of assisted living facilities and well being of cognitively intact elderly. Multiple case study methodology will be followed by selecting facilities varying in size and plan layout configurations. The size of facility, plan layout configuration, walking distances between resident’s room and common areas, accessibility and presence of neighborhood amenities will be the independent variables of this study. Well-being outcomes (dependent variables) will be collected by structured observation of resident’s use of common spaces and their social interactions. Personal digital assistants that run geographical information software will be used to record location and behaviors of residents in social areas. Residents will be asked about their perceptions of facility and neighborhood in an interview. Caregivers will be asked to provide non-medical information and make behavioral assessments about each resident. Research findings will be transformed into design guidelines and an assessment tool for assisted living settings. Currently, no tool exists that links well-being of elderly and physical environment of assisted living, with the potential of affecting policy. Resul
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The first indoor grow light control solution to optimise photosynthetic processes in plants by dramatically cutting energy costs' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

At Laava Tech, we are determined to make vertical farming a profitable and sustainable business to feed the increasing population in growing urban areas. It is crucial for vertical farmers to save energy and cut down on lighting costs, since the vast majority of their revenues are used to pay the electricity bill. As a result, only very few vertical farms are profitable today. Our solution, FarMind is an entirely new LED Grow Light System based on AI, capable of adjusting the light emitted by each LED light of a farm to match the exact needs of the plant lit underneath. FarMind reduces the lighting energy bill of vertical farms by up to 75% (vs LED grow lights), whilst increasing crop yields by up to 20%. Unlike other LED grow light technologies, which focus on light efficiency and crop optimisation, FarMind focuses on the real photosynthetic need of the plant. FarMind will revolutionise the vertical farming industry by vastly increasing its profitability. We will provide a drop-in solution, compatible with the existing infrastructure for our customers, indoor farmers. Our main revenue model will be based on providing FarMind as a service to leading farms. Our model will not only allow farmers continued access to the best technology, but also give them an immediate return on investment. Thanks to FarMind, vertical farming will be able to overcome its final growing pain to transition from niche solution to leading urban supplier of sustainably produced fruit and vegetables.


**Keywords:** Indoor Farming
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'European Research Infrastructure for Marine Bioprospecting' (EUREMAP).

assistant: **Concept**

The main objective of the EUREMAP consortium is to optimise the marine bioprospecting pipeline in Europe to enable state-of-the-art research and capacity for both academia and industry. The ambition is to leverage strengths available within European Research Infrastructures (RIs) and to align capacities and resources of the multidisciplinary field of marine bioprospecting. Hence, to increase the competitiveness of marine natural products in the field of drug discovery and to strengthen the blue bioeconomy in Europe, we will assemble a new pipeline that aligns and integrates the existing technical capacities and multidisciplinary expertise of the three European RIs - EU-OPENSCREEN (EU-OS), EMBRC and ELIXIR - in the field of marine natural products discovery. EUREMAP will develop a unique trans-RI integrated service in an European priority area, the blue economy. The pipeline will be an important part of the European blue growth strategy to stimulate economic growth through innovations in marine biotechnology. The potential for innovations and value creation in the blue biotechnology sector is high, and the sector is characterised by being multidisciplinary, knowledge-intensive and built on technology. Building a new European transnational RI service platform to support the competitiveness of an academic and industrial community in all aspects of this multidisciplinary field. EUREMAP will bring together an experienced, multidisciplinary consortium across three RIs to support and enable the discovery of novel bioactive natural products from marine organisms by utilizing novel technology to improve the capacity of European RIs.


**Keywords:** Marine bioprospecting, blue bioeconomy, drug discovery, bioinformatics, marine organisms, bioactivity screening, biotechnology, RI,