RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Genetic and immunological studies in HIV+ European and African long term non progressors' (GISHEAL).

assistant: **Concept**

A minority (<5%) of all HIV-1 infected individuals have been defined as long-term nonprogressors (LTNP) in that they maintain exceptionally prolonged survival in the absence of clinical symptoms and without receiving antiretroviral therapy. Several cohorts of LTNP have been identified in Europe and national networks have been formed in France and Italy to better study their particular features. GISHEAL is the first collaborative European consortium focusing on the LTNP condition with particular regard to the host genetic background and gene expression profiling and to the adaptive and innate immunological responses to the infection. A common database will be formed by merging two existing national (French, Italian) databases supplemented with additional data collected from LTNP cohorts currently followed-up in the UK and Uganda. A genome-wide approach based on screening of >100,000 single-nucleotide polymorphisms (SNPs) followed by proper validation steps will lead to the potential discovery of novel genetic polymorphisms linked to LTNP in addition to those already described. Their consequence in terms of gene expression will be studied in different populations of leukocytes (CD4, CD8, monocytes, NK and T cells) by microfluidic cards based on multi-parametric real-time PCR (TaqMan) in selected LTNP and control chronic progressors (CP). The adaptive T lymphocyte (CD4, CD8) immune responses as well as the NK cell and T cell responses to HIV will be studied in LTNP and CP. The functional consequences of the potentially novel genetic and post-genomic correlates of therapy-independent long-term non-progression in HIV infection will be also investigated in these immune cells. A multivariate analysis will allow definition of the best correlates of non-progression that could be
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Dental morphology across the tooth row: Geometric morphometric analysis of multiple tooth positions, reconstruction of missing teeth, and implications for hominin taxonomy.' (TOOTHROW).

assistant: **Innovation**

Our understanding of human evolution depends on reliable taxonomic identification of fossils and an understanding of their phylogenetic relationships. Teeth are a key source of evidence: they are well-preserved in the fossil record and their morphology is under strong genetic control. State-of-the-art methods involve 3D morphological analysis of internal dental structures, but due to statistical challenges and fossils frequently missing teeth, these analyses focus on each tooth position individually. This means that important aspects of variation across the tooth row are not captured, and as a result, key issues in hominin systematics remain unresolved.TOOTHROW will overcome these limitations by developing a novel methodological framework to analyse the morphology of the entire tooth row in a single analysis, even in incomplete specimens. I will use cutting-edge geometric morphometrics and multivariate statistics to estimate the morphology of teeth missing from fossil specimens, providing a powerful reconstruction tool. Morphological analysis of the complete dental arcade will be developed and tested on large extant hominoid samples, before being applied to two fossil hominins: Homo habilis and Homo naledi. Both species are central to our understanding of human evolution, yet the relationship between them and other hominins remains unresolved.The R-based analytical toolkit developed by TOOTHROW will advance applications of geometric morphometrics to include multiple skeletal elements, with applications in fields such as palaeontology, vertebrate morphology and forensics. The University of Vienna, home to a leading competence centre in morphometrics, and embedded in large networks of anthropological and evolutionary research, is the ideal host for this project. Results w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Wind and Turbulence Radar for Offshore wind energy' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The project studies the use of a radar based technology to increase revenues and decrease maintenance costs of offshore wind-farms by providing a technology that help wind parks predict and adapt to the wind. Modern wind turbines are adjustable. The angels of rotors and blades can be changed. This is done by a control system optimizing production on a wind park level, or an even greater level. The wind park operator have several objectives to optimize for with the help of wind data. One is to reduce maintenance costs. Sudden wind bursts damage wind turbines, through identifying such wind bursts from a distance the wind park control system can adjust the angles of the blades to deflect the power of the wind. A second is to be able to predict energy output more accurately. This is important as wind park operators often have energy delivery contracts and are penalized if they deliver more or less than predictions. Predictions become more accurate when wind park operators have data on and understanding of the wind resources. A third objective is to harmonize all wind turbines in the park to get the highest possible stable output. This is also based on data on and understanding of the wind resources. There is substantial economic benefits to be gained through improved operation of wind parks.  The yearly cost improvements from the system in the European offshore marked alone is estimated to 275 M EURO in 2020 and over 1 000 M Euro in 2030. There is also a potentially much larger positive societal impact. Improvements in the cost-efficiency of wind will help it reach a tipping-point where it is driven forward through commercial motivations rather than government aid. The company have recently completed a major (approx. 1,4 M EUR) government funded research project, and tested
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Identifying fingerprints of fragility in complex ecosystems'.

assistant: **Innovation**

Ecosystems are deteriorating at unprecedented rate. Climate change is threatening their functioning and the vital services they provide to human societies, imposing an urgent need to understand how they are coping with and reacting to global change. The complexity of ecosystems, however, makes predicting their fragility a difficult endeavor. FRAGILEPRINTS: Identifying fingerprints of fragility in complex ecosystems focuses on a critical scenario in ecosystem degradation: large and abrupt transitions following gradual environmental changes, observed across ecosystems worldwide. Despite important progresses, key knowledge gaps remain in our understanding of the mechanisms underpinning these transitions, making them notoriously difficult to predict. Current research relates them to the presence of Multiple Stable States (MSS), with small perturbations able to induce large shifts from healthy, species-rich communities towards deteriorated ecosystem states. Understanding of MSS, however, is based on simple models that largely ignore the role of species diversity and interaction complexity, highlighting an extremely relevant gap in our capacity to uncover potential abrupt transitions in species-rich ecosystems. To address this gap, FRAGILEPRINTS will investigate the emergence of MSS in complex ecosystems by combining a novel bottom-up and top-down interdisciplinary approach: increasing complexity in few-species MSS models and adding structure to random high-dimensional complex networks. The combination of the two, each applying mathematical models and numerical simulations confronted with experiments and whole-ecosystem data, will allow the identification of fingerprints of ecosystem fragility: conditions, common across ecosystems, related to the presence of MSS and potential
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Neuronal basis of group cooperation and social ties in monkeys and humans' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

The negative impact on society's mental health by social distancing during the current COVID-19 pandemic highlights the importance of social interactions in maintaining a healthy life. Reputation, cooperation, and an individual's social ties play a crucial role in social interactions. My proposal will examine the interdependence and neural correlates of these psychological processes. I hypothesize that a social tie's strength influences cooperative behavior; similarly, cooperative behavior fosters social ties. Further, I hypothesize that the interplay of neuronal activity in the dorsomedial prefrontal cortex (dmPFC) and insular cortex underpins these processes. My recent studies of human and non-human primate dmPFC showed its involvement in encoding social processes. Yet, its role in cooperation and social tie formation is unclear. To test these hypotheses, we will first characterize the neuronal representations underlying group cooperation. Second, we will identify the neuronal mechanisms underlying fundamental behavioral processes in forming and maintaining social ties during naturalistic interactions in monkeys. Third, we will compare in a new world monkey and humans the association between group cooperation and social ties? formation and maintenance. This new line of investigation will shed light on how elementary social computations during group interactions such as social dilemmas are computed at the single-neuronal and population levels within the primate brain. Overall, this proposal will allow us to study social interactions in a way that has never been done before and will lay the foundation of future work in my independent laboratory. By using an innovative approach, this project aims to identify the brain's mechanisms underlying the formation of non-kin and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Nanostructured waterborne polymer films with outstanding properties'.

assistant: **Concept**

The development of many industrial sectors (coatings, adhesives, cosmetics and additives for paper and textiles) is limited by the inability of existing technology to produce nanostructured polymer films via a sustainable technology. The objective of this industry-led project is to make possible a generation of radically-new products by developing a technology platform to produce films with controlled nanostructure without organic solvent or residual monomer, in compliance with impending European directives on solvent emissions. The breakthrough idea is to use waterborne nanocomposite (polymer-polymer and polymer-inorganic) nanoparticles with carefully controlled structure as building blocks for the films. Nanoparticle production, processing and properties (including biocompatibility) will be studied in an integrated technology platform. Industrialists will ensure the proper scale up and product development. Among the expected breakthrough properties are good adhesion to porous substrates, increased hardness, strength and wear-resistance with low dirt pick-up, higher impermeability to liquids and gases, and greater fire resistance. The technology will offer energy savings in production and transport. To achieve this objective, work programmes will integrate the contributions of 9 EC companies (including 3 SMEs) with that of academics from 12 centres of excellence. To retain and nurture European technological excellence, the project integrates activities in training and education along with programmes to exploit and disseminate the knowledge in the wider communities. As a result of the project, European industry - especially SMEs - will benefit from the introduction of new, value-added products into a competitive world market. As an example, in coatings alone there are 2
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'A Decision Support System incorporating a validated patient-specific, multi-scale Balance Hypermodel towards early diagnostic Evaluation and efficient Management plan formulation of Balance Disorders' (EMBalance), addressing dissemination and exploitation.

assistant: **Impact**

Human balance is achieved and maintained by a complex set of sensorimotor systems that include sensory input from vision, proprioception and the vestibular system (motion, equilibrium, spatial orientation); integration of the sensory input; and motor output to the muscles of the eye and body. Failure at the level of the sensory inputs or at the integration of the sensory information by the central nervous system may lead to a variety of age spanning diseases which affect balance. This complexity leads to undiagnosed or under-treated patients with balance disorders for long periods and results in large socio-economic costs.The EMBalance project aims to extend existing but generic and currently uncoupled balance modelling activities leading to a multi-scale and patient-specific balance Hypermodel, which will be incorporated to a Decision Support System, towards the early diagnosis, prediction and the efficient treatment planning of balance disorders. Various data will feed the intelligent system increasing the dimensionality and personalization of the system. Human Computer Interaction techniques will be utilized in order to develop the required interfaces in a user-intuitive and efficient way, while interoperable web-services will enhance the accessibility and acceptance of the system. The vision extends to the experimental and clinical validation of the project outcomes with existing and newly acquired data (by conducting small scale clinical trials), and includes showcases in balance disorders diagnosis, prediction, treatment and follow-up in normal and micro-gravity environments.The final outcome will be a powerful web-based platform provided to primary and secondary care physicians across specialties, levels of training and geographical boundaries, targeting wider cl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Evaluation and Valorization of Social Services for a Sustainable Transition' to be submitted under Horizon Europe.

assistant: **Abstract**

The EVOSST project aims to improve the efficiency and understanding of social services within the European Union, aligning with the European Pillar of Social Rights and the EU's long-term budget for social inclusion and cohesion. The project focuses on developing advanced models for a comprehensive life-course impact assessment, providing insights into the long-term effects of social services, and covering healthcare, childcare, long-term care, education, and inclusion. This aligns with the EU's ambition for sustainable development and inclusive growth, moving towards a 'beyond GDP perspective'. The integration of well-being metrics reflects the EU's emphasis on improving the quality of life, including health and education, and enhancing societal well-being and social cohesion, along with the development of an integrated policy framework for social services echoes the EU's strategic direction for streamlined and effective social service delivery. EVOSST's integration of technological impact and digital technology in social services is an applied vision aligning with the European Commission's Digital Education Action Plan (2021-2027). The project applies this directive to the broader realm of social services, utilizing technologies to enhance service delivery, assessment, and user experience. The project's ambition is not only to enhance the effectiveness of social services but also to revolutionize the way their impacts are measured and understood, informing more effective policies and practices.


**Keywords:** Social Economy, Social Analytics, Artificial Intelligence, Predictive Analytics, Virtual/Augmented Reality, Cultural Inclusion, Cross border Collaboration
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Satellite Seafloor Survey Suite'.

assistant: **Innovation**

4S will address a current data and solution gaps from coastal and offshore stakeholders, which are the ability to generate and access spatial and recent information on seabed, such as benthic habitat, morphology, depth and change and trends. Digital information on these are crucial to respond to EC maritime directive, environmental impact studies and engineering offshore activities. We will address this gap by developing an online, cloud based software, named 4S – Satellite Seafloor Survey Suite – which empowers the users to benefit from satellite capabilities and specific aquatic EO algorithms. 4S Suite will have APIs allowing to integrate it into hydrographic software and user’s workflows, as will developed and demonstrated. 4S will harness Copernicus data together with US satellite lidar data and – optionally – integrate client airborne (drone) imagery and on-site data. The underlying algorithms, which will reach highest TRL level during the project duration, will address aspects of physical modelling, machine learning and sensor fusion procedures and will introduce breakthroughs of the current state of the art. Both, algorithm innovations and the webapp, will be jointly designed and evaluated with the users, of which some are part of the project team. Other stakeholders, many of which have signed supporting letters, will participate in 7 use cases which cover four countries, the Caribbean and several selected sites globally. With this intense evaluation and co-design we will achieve a reliable evaluation of the process and global outreach to the offshore and coastal stakeholders. The development of a sustainable business based on 4S will be driven by the industry partners, which contribute with 52% of the workload. Based on the existing solution gap we expect a cont
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Decoding spatio-temporal omics in progressive neuroinflammation' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Multiple sclerosis (MS) is a paradigmatic progressive neuroinflammatory disease characterized by multiple lesions across the entire central nervous system including both gray and white matter areas. Deconvoluting the spatio-temporal cellular and molecular landscape is therefore key to understanding underlying disease mechanisms and to develop cell-type specific therapies. The DecOmPress proposal is about integrative human and mouse single-cell genomic strategies to track-down reactive cellular states in compartmentalized progressive neuroinflammation. DecOmPress has two major research tracks (RTs).RT1 is an MS tissue discovery pipeline utilizing single-nucleus RNA and open chromatin sequencing. RT1 is about developing novel integrative computational tools to process sequencing data from different anatomical lesion areas implementing a large multiplex single-nucleus genomic dataset from the anterior visual system. RT1 is also about decoding compartmentalized inflammation in meningeal versus perivascular tissue niches.RT2 is a functional validation pipeline utilizing complex transgenic and disease mouse models as well as human organoids in combination with single-cell physiology and genomics. RT2 is about dissecting glial-intrinsic mechanisms at the chronically inflamed white matter lesion rim focusing on MS-specific oligodendrocyte and microglia subtypes. RT2 is also about decoding neuron subtype specific pathologies focusing on projection neurons and the contribution of local (meningeal) and distant (white matter tracts) inflammation and demyelination to cell-type specific neurodegeneration.In summary, DecOmPress is a highly innovative and fully translational multidisciplinary proposal aiming at identifying novel cell-type specific disease mechanisms and therapeutic tar