RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Molecular robots for catalytic processes', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The aim of the proposal is to try and develop a new catalytic cycle for the asymmetric synthesis of epoxides and aziridines from electron deficient alkenes. This class of epoxides/aziridines is important because the products are versatile synthetic intermediates in the synthesis of agrochemicals and pharmaceuticals and because of the growing demand to produce enantiomerically pure compounds. The key to our strategy involves designing a catalysts that acts as a molecular robot: one arm picks up the alkene and the other picks up the oxidant. Once both components are attached to the catalyst a pseudo intramolecular reaction occurs to give the epoxide/aziridine and decomplexation gives back the catalyst. As only one arm can pick up the alkene and only one can pick up the oxidant and because the reaction can only occur on the robot template, high enantioselectivity should result.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'A Peer learning based pilot scheme for using the H2020 Seal of Excellence at national level' (SME-SEALING) targeting Horizon 2020.

assistant: **Abstract**

The Seal of Excellence (SoE) is a new initiative launched at European level in October 2015 that aims to foster synergies between H2020 and other funding resources, mainly at regional and national level. The idea behind this SoE is to offer a gateway to companies and organizations across Europe that apply to the Horizon 2020 Programme and despite of meeting all the stringent thresholds of the calls, they can not be funded due to the lack of available budget.The first instrument where the Seal of Excellence has been implanted is the H2020 SME instrument. In that context, this Seal of Excellence linked to the SME instrument proposers offers a clear added value to national and regional authorities as a reliable filter of promising companies with international ambition, meriting an European funding but unable to achieve it, but still worth to be supported.For the phase 1, during 2015, a number of countries and regions have already been able to launch at national or regional level support mechanism for the Seal of Excellence phase 1 holders, mainly channelled through the “de minimis” regime.For the phase 2, the paths are not so direct considering Technology Readiness Level of 6 as starting point.This is the rationale of this proposal: to use the peer learning advanced methodology, proposed by the topic, together with the current tools from the lean start-up methodologies to develop and test different approaches to the valorisation of the Seal of Excellence for the SME instrument phase 2 within a small consortium of national innovation agencies (CDTI (ES), Enterprise Ireland (IE) and TEKES (FI) with a long tradition of collaboration among them, a strong know-how on the SME instrument and in charge of national programmes in support of SMEs through grants, loans and/or equity.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Assess implementations in the frame of the cities-of-tomorrow programme' (ASI) under Fifth Framework.

assistant: **Objectives**

One goal in connection with implementation of policies and measures in the frame of the Key Action Cities of Tomorrow (CoT) is to improve life quality (LQ) in the cities. ASI will help to improve assessment and appropriate consideration of LQ assessment results in connection with urban transport and mobility policies. The focus of the project will be on the subjective part of LQ. Many measures have been implemented so far in the frame of this key action. In ASI, we want to select five CoT implementation-sites in different parts of Europe and to find out how LQ aspects are assessed and taken care in these areas. Based upon the results of the evaluation of these sites we will develop a toolbox to assess the LQ effects of proposed and implemented policies and measures which will be tested in a pilot- study. Moreover, the concept for a data bank for the storage of qualitative data of LQ assessments and measures based upon them will be developed.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'INTEGRATION OF MANUFACTURING SYSTEMS FOR MASS-MANUFACTURE OF MINIATURE/MICRO-PRODUCTS'.

assistant: **Innovation**

The overall objective of the project is to develop an integrated solution for European miniature/micro- manufacturing and related industries - an integrated manufacturing facility for mass-manufacture of miniature/micro-products, and a technology transfer/training package for transforming EU industries. A multi- discipline (horizontally) and integration (vertically) approach will be used for the implementation of the project, based on the mobilisation of the sufficient critical mass of resources. Research will be conducted to resolve fundamental and technological issues concerning the mass-manufacture of miniature/micro-products with a scale of manufacture, which has not been achieved, so far, by any organisations. Demonstration of the mass- manufacturing facility to be developed will be subjected to validation trials and production applications; knowledge and technologies generated will directly be transferred to the targeted groups, which will be effected by organising three demonstrations, four training-programmes and two major public events.The project will result in significant numbers of innovations, which will represent breakthroughs - innovative, flexible and intelligent tools, machines, and handling-devices concepts and designs for miniature/micro- forming and machining; first, integrated manufacturing facility for mass-manufacture of miniature/micro-products which incorporates high-rate material-conversion technologies into the systems. The development addresses the objectives of the call FP62002-NMP-1" which gives emphasis on the "New production concepts, supporting new products, processes and services", "Industrial systems of the future", "Transformation of the European industry towards a more knowledge-based and added value industry" and "Improved competiti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Epigenetic regulation of gene expression: transgenic mouse model systems of variable expressivity in genetic disease' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Epigenetic control of gene expression by DNA methylation and chromatin mechanisms plays a crucial role in normal development, genetic disease, and cancer. It is therefore important to identify genetic factors that control methylation and chromatin structure, as these factors are likely to contribute to cancer susceptibility and to predisposition and expression of many genetic diseases, and are likely to play an important role in multifactorial causes of disease. The centres that are involved in this proposed Epigenetics Network have previously developed transgenic model systems in the mouse that show variable transgene expression and repression associated with DNA methylation and chromatin compaction which is controlled by genotype-specific modifier genes in the genome. Here it is proposed to use three different transgenic systems as well as endogenous gene targets of epigenetic control, to genetically characterise and map modifier genes which are responsible for this variable expression and methylation. The genetic fine mapping of these modifier genes will eventually lead to their isolation by positional cloning. The developmental and lineage-specific action of modifier genes will be analyzed, and embryonic stem (ES) cells will be isolated that carry transgenic targets. This will eventually establish a test system for candidate modifier genes. The sequence targets of modifier action will be defined using the already established transgenic mouse strains. Endogenous target sequences of modifier action will be isolated using RDA (Representational Difference Analysis). Mapping and characterisation of modifier genes will lead to a better understanding of the epigenetic mechanisms of gene regulation. Since these genes are likely to play a major role in multifactorial disease
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Tracing Bright and Dark Matter with the New Generation of Large-Scale Surveys' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

'Tracing matter' in astrophysics is about finding the very ingredients and recipe of the Universe: how did the chunks of matter we see (stars, galaxies, quasars, etc) and don't see (the so-called 'dark' matter) come to form and evolve into today's sky?Observational cosmology - the field of astrophysics we propose to cover in this High-Level Scientific Conference - has become a prominent area of European scientific research in recent years. Observational cosmology has indeed undergone a spectacular expansion in the last 10 years, due to the great technological progress in astronomical instrumentation. New sensitive, wide-field detectors and multi-object spectrographs on large telescopes now provide astronomers with a wealth of data at all wavelengths of the electro-magnetic spectrum. After decades of mostly theoretical research, due to the sparsity of the data, cosmologists are now flooded with truly astronomical amounts of images and spectra, allowing them to reconstruct three-dimensional pictures of increasing volumes of the Universe.In the 90's, spectroscopic surveys of a few thousand objects unveiled, for the first time, a patch of the distant Universe. A new generation of surveys, sampling millions of galaxies, is now underway, currently tracing the baryonic content of the Universe to unprecedented distances, allowing us to probe the very origin of the Cosmos. Results from these surveys will become available next year. We are thus planning to organize a High-Level Scientific Conference in Marseille (France) in June 2001, to bring together the leading experts and the many up-and-coming young researchers in the field. The proposed meeting aims at offering the community the opportunity to present these exciting new discoveries, to discuss their theoretical interpretati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Rna-based anti-hiv strategies - exploiting the hiv codon bias' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Research objectives and content The project in general aims at the development of some novel anti-HIV strategies. In particular, the extreme codon bias that HIV exhibits will be exploited for the first time and appropriately engineered tRNAs will be used to induce multiple amino acid mutations to HIV proteins in HIV infected cells without affecting the cellular proteins. In addition, a library of ribozymes targeted against several parts of the HIV genome will be generated and in vivo selection for optimal ribozymes will be carried out. These ribozymes will then be used in the context of HIV-based vectors, whose genes have been codon optimised, in order to provide a powerful anti-HIV gene therapy strategy. The use of HIV vectors has the advantages of targeting to HIV succeptible cells and of inhibition of viral spread as well. Furthermore, this strategy ensures efficient delivery of the vectors through the CD4+ population. The above two strategies exploit the codon bias that HIV exhibits to produce some entirely novel anti-HIV therapeutics. This is the first time that this unusual feature of HIV has been exploited for therapeutic purposes. Furthermore, these studies could also add to our knowledge on HIV gene expression and replication. Training content (objective, benefit and expected impact) The training will include a great variety of modern molecular biology methods ( eg DNA manipulations, virus production and mammalian cell transduction, RT-PCR e.t.c. ). The benefits from it are expected to be many, since the field in which I will be trained is expected to become a major component of the biotechnology and pharmaceutical industries. The overall work is also expected to have a significant impact on gene therapy technology. Links with industry / industrial relevance (2
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Atmospheric Gas-to-Particle conversion' (ATM-GTP) targeting Horizon 2020.

assistant: **Abstract**

Atmospheric Gas-to-Particle conversion (ATM-GTP) is a 5-year project focusing on one of the most critical atmospheric processes relevant to global climate and air quality: the first steps of atmospheric aerosol particle formation and growth. The project will concentrate on the currently lacking environmentally-specific knowledge about the interacting, non-linear, physical and chemical atmospheric processes associated with nano-scale gas-to-particle conversion (GTP). The main scientific objective of ATM-GTP is to create a deep understanding on atmospheric GTP taking place at the sub-5 nm size range, particularly in heavily-polluted Chinese mega cities like Beijing and in pristine environments like Siberia and Nordic high-latitude regions. We also aim to find out how nano-GTM is associated with air quality-climate interactions and feedbacks. We are interested in quantifying the effect of nano-GTP on the COBACC (Continental Biosphere-Aerosol-Cloud-Climate) feedback loop that is important in Arctic and boreal regions. Our approach enables to point out the effective reduction mechanisms of the secondary air pollution by a factor of 5-10 and to make reliable estimates of the global and regional aerosol loads, including anthropogenic and biogenic contributions to these loads. We can estimate the future role of Northern Hemispheric biosphere in reducing the global radiative forcing via the quantified feedbacks. The project is carried out by the world-leading scientist in atmospheric aerosol science, being also one of the founders of terrestrial ecosystem meteorology, together with his research team. The project uses novel infrastructures including SMEAR (Stations Measuring Ecosystem Atmospheric Relations) stations, related modelling platforms and regional data from Russia and C
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Laser vibrometry network : systems and applications' (LAVINYA).

assistant: **Innovation**

LAVINYA aims at improving and disseminating the knowledge on laser techniques for vibration measurement with reference to both laser Doppler vibrometers and full field techniques. The partnership, composed of universities, research centres, instrument manufacturers and end-users, involves some entities of worldwide relevance. LAVINYA will achieve its objectives by means of 7 work packages. The activities will consist in short courses organisations, presentation, and workshops, each devoted to a particular subject. The planned activities aim at disseminating scientific know-how, training and innovative education of young researchers and end-users and finally at the enhancement of the highly quality technology and to its application to innovative areas. As a result the interaction between different actors, which complement each other and are transversally linked by the same interest laser vibrometry, will enforce the scientific and technological leadership of Europe in this field.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Quantum Optics for Quantum Information Processing', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

We propose a theoretical investigation of the practical use of quantum optical systems for the implementation of quantum information processing. Employing a range of techniques and approaches, we will pursue the general scientific objective of identifying and characterizing optimized procedures for high-fidelity, robust and efficient quantum memories and gates involving atomic and condensed-matter systems. The main focus will be on coherent control of individual atoms in microscopic potentials. Existing gat e proposals will be improved and new schemes will be proposed, relying on one hand on interaction mechanisms (e.g., molecular couplings) not yet fully exploited for enhancing entangling operations, and on the other hand on quantum optimal control methods t o increase gate fidelities. Particular attention will be paid to the choice of qubit degrees of freedom and of manipulation procedures intrinsically less sensitive to decoherence sources and to imperfections in the control of the system, in order to relax experimental constraints for effective quantum computing. Innovative qubit manipulation and interfacing mechanisms in the context of mesoscopic condensed matter will be explored, in the sense of coupling to nanofabricated structures like quantum dots, supe rconducting devices and nanotubes. The training objectives concern on one hand deepening and broadening the applicant¿s core competence in quantum optics and atomic physics applied to quantum information processing, and on the other hand complementing it w ith new knowledge in the field of condensed-matter mesoscopic systems and with new skills in the management of international scientific collaboration at the extra-European level, in view of consolidating prospects for independent research in the context of the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'SEMANTIC AND COGNITIVE DESCRIPTIONS OF SCENES FOR REASONING AND LEARNING IN AMBIENT INTELLIGENCE' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

A challenging goal in cognitive vision research deals with integrating quantitative and qualitative modes of representation; in particular, quantitative computer vision techniques for object recognition, tracking and motion analysis etc., and qualitative spatio-temporal representations to abstract away from unnecessary details, noise, error and uncertainty.This project is aimed at developing a semantic and cognitive description of real-world scenes captured at the intelligent building where the Spatial Cognition Research Centre at Universität Bremen is located. From the cameras and other sensors integrated in the building, the most efficient computer vision techniques will be applied for recognition of objects and human pose. A qualitative model for describing scenes and spatio-temporal changes will be defined in order to manage uncertainty and to apply qualitative reasoning models for inferring further information. Then, the qualitative descriptions obtained will be provided with ontological meaning for symbol grounding in order to provide ‘scenario understanding’ to software or robotic agents. To enhance human machine communication, the qualitative and semantic descriptions obtained will be translated to natural language for human understanding and a narrative description will be provided to the end-user for reading or for listening to by means of a speech synthesizer program. Finally, as a truly cognitive system must have the ability to learn from models built from sensor inputs, a framework for high-level (symbolic) learning of human-object interaction in temporal events will be designed.