RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'NATURE’S FIRST LEAD IN THE FIGHT AGAINST MESOTHELIOMA:THE TOTAL SYNTHESIS AND BIOLOGICAL EVALUATION OF JBIR-23 AND RELATED COMPOUNDS'.

assistant: **Concept**

Human malignant pleural mesothelioma is an aggressive (fatal) lung cancer which is always associated with previous asbestos exposure.  Typically symptoms do not appear until 35-40 years after the original exposure, with life expectancy then 12-18 months.  Given the great use of asbestos during the 20th century (before its long overdue ban in 1985) and this long latency period, it is no surprise that cases of mesothelioma continue to rise. There is no known cure for mesothelioma: traditional chemotherapeutic cancer treatments have had little impact on the disease and radiotherapy or partial pleurectomy have only very limited impact on life expectancy.  However, very little in the way of mesothelioma research is taking place, as it is frequently not considered to be a ‘big enough market’ (<1% of all cancers in the U.K.) and consequently there are currently no drugs in development for this disease.  A second reason for this is that there have been no reported good lead compounds (natural products) as a starting point for the drug discovery process.  Until now.First isolated from Streptomyces sp. AK-AB27 in 2008, JBIR-23 possesses a unique structural architecture, hitherto unobserved in Streptomyces extracts. Furthermore, JBIR-23 is unique, in that it is the first natural product to be isolated to exhibit activity against human malignant pleural mesothelioma. This is an amazing breakthrough: the isolation of the first natural product to be highly active against mesothelioma is crucial, providing a precious lead compound for investigation.The aim of the project, therefore, is to investigate the synthesis and anti-mesothelioma activity of JBIR-23 and to prepare further analogues to commence structure-activity studies. This will be the first study of this kind.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Energy-aware System-on-Chip design of the HIPERLAN/2 standard', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

EASY deals with the implementation of a low power/cost System-on-Chip (SoC) that handles both the baseband modem and critical functionality of the DLC layer of the very promising and emerging HIPERLAN/2 European standard. No such a SoC device exists in the market. The implementation will contain the hardware-software system's mapping, the development of the real-time software for the system's parts that will be executed on the used processors, the design of custom hardware blocks which will implement critical system's parts, the integration of the hardware-software blocks, the board development and the demonstration of the system. During the project, a low-power design methodology for wireless protocol applications, accompanied with prototype tools, will be developed. This methodology contains novel power optimisation techniques related to the system's embedded software, the hardware-software mapping, the data transfer/storage and the memory/bus architecture.Objectives:The main objectives of the EASY project are:- To develop a cost/power efficient heterogeneous System-on-Chip processor, that handles both the baseband modem and critical functionality of the DLC layer of the HIPERLAN/2 protocol stack.- To develop a low-power design methodology for the low-power implementation of wireless protocol applications on heterogeneous System-on-Chip platforms. This methodology will contain novel power optimisation techniques related to the system's embedded software, the hardware-software mapping procedure, the data transfer and storage, and the memory/bus architecture.- To develop prototype tools, based on the developed low-power design methodology.- To exploit and disseminate the results of the project.Work description:The EASY project aims at developing a power/cost efficient S
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Composition Operators on Spaces of Dirichlet Series and Algebrability in Banach Algebras' (CoDSABA).

assistant: **Concept**

This project will investigate timely questions on composition operators acting on Banach spaces of Dirichlet series, and on hypercyclic algebras. These topics are currently the subject of great mathematical interest, however fundamental questions remain unresolved in the respective fields.   The first objective is to advance the theory of Banach spaces of Dirichlet series by employing operator theoretic function theory to understand the topological structure of the set of composition operators acting on these spaces. An effective method of achieving this is to study approximation numbers of differences of composition operators. This project will determine the rates of decay of approximation numbers of differences of composition operators acting on spaces of Dirichlet series, and characterise the linear combinations of composition operators acting on general Banach spaces of Dirichlet series.   The second objective is to investigate the algebraic structure contained in the set of hypercyclic vectors of multiplication operators acting on the Banach algebra of compact operators. Hitherto work in this area has mostly been in the setting of Frchet algebras, so this project will advance the theory for Banach algebras, and ultimately to identify whether every Banach algebra supports a hypercyclic algebra.   Interest among the wider mathematical community in the findings of this project stems from its natural connections to some of the most important open questions in mathematics. In particular the study of Hardy spaces of Dirichlet series is related to the Riemann zeta function, and the investigation of hypercyclic algebras has a natural connection to the Invariant Subspace Problem. The scientific breakthroughs resulting from this project will also impact on a wide scientific
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'IT[t] Simply Works'.

assistant: **Objectives**

The primary goal of the proposed effort is to generate a set of innovative research topics on thenotion of simplicity as a driving paradigm in ICT development, maintenance and use. We believethat the philosophy of simplicity is strategically important, yet poorly understood, and rarelysystematically applied. Instead, design principles attempt to focus on increased functionality withinthinly disguised complexity, often at the expense of life cycle costs and total cost of ownershipissues (e.g., training, system malfunctions, system upgrades). Often designers are unaware of thetradeoffs and impacts. With the increased use of ICT in such socially critical areas such ashealthcare, society can no longer afford systems that do not perform as specified. We believe that an understanding of simplicity is the key. Simplicity is foundational, its essence fundamental to many desired characteristics of ICT systems such as reliability, usability and trust. Thus, we believe that knowledge gained through research on simplicity can provide the EU a sustainable competitive advantage. To gain this knowledge we must ask the right questions, we must develop the proper research directions. To do so, the IT Simply Works team will organise a set of multidisciplinary experts to assist in surveying key research communities about their understandings and vision of the philosophy of simplicity. Only through such a multidisciplinary approach can we hope to achieve a basic and yet thorough understanding of the important issues to be addressed. The results of this effort will be presented in a final report elaborating the vision of simplicity in ICT and proposing topics, initiatives and modalities for future-directed foundational research and its transformation for benefitting Europe's citizens, busin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Laboratory Experiments on Magnetic Phenomena in Geo- and Astrophysics'.

assistant: **Objectives**

Cosmic magnetic fields, including those of planets, stars, and galaxies, are being generated by the homogenous dynamo effect in flowing electrically conducting fluids. Once produced, these fields may play an active role in cosmic structure formation by fostering angular momentum transport and mass accretion onto central objects, like protostars or black holes, by means of the magnetorotational instability (MRI). Complementary to the decades-long theoretical research into both effects, the last years have seen great progress in respective experimental investigations. The dynamo effect had been verified in three liquid sodium experiments in Riga, Karlsruhe and Cadarache. The helical and the azimuthal versions of the MRI, as well as the current-driven Tayler instability (TI), were demonstrated at Helmholtz-Zentrum Dresden - Rossendorf (HZDR). Here, I propose to make three further breakthroughs in this research field. First, I plan to demonstrate dynamo action based on a precession driven flow of liquid sodium in a cylindrical vessel. Besides thermal and compositional buoyancy, precession has been discussed as a complementary power source of the dynamos of the Earth, the ancient Moon, and other cosmic bodies. A second experiment will deal with magnetically triggered flow instabilities of astrophysical importance, with the main focus on attaining standard MRI, and various combinations of MRI and TI. Both experiments will be carried out at the DRESDYN facility at HZDR which has been conceived by me and which will enter into operation in 2019. In contrast to these well-advanced experimental concepts, my third liquid sodium experiment, which aims at showing the magnetic destabilization of rotating flows with radially increasing angular velocity, still requires more numerical si
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Optical Ultrasound Imaging for Real-time Guidance of Intracardiac Procedures' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

This European Research Council Proof of Concept grant is focused on translating a new medical device for interventional cardiology from a proven laboratory prototype to a commercial prototype. The core innovation in this medical device is a new type of ultrasound imaging probe that can be readily integrated into medical devices to guide minimally invasive procedures. Current generation probes, which are based on electrical methods of ultrasound generation, involve complex fabrication processes that make them prohibitively expensive for many applications. The technology platform underlying the new ultrasound imaging probes includes both optical transmission and reception of ultrasound waves. The new probes are fabricated with inexpensive optical fibres, using simple techniques that are highly scalable for large-volume production. With fabrication costs that are approximately 10 times lower than those of current generation probes, they will address large under-served markets in which current generation probes are too expensive to be reimbursed. They can be readily integrated into small diameter needles and catheters, which make them attractive for a wide range of clinical applications. The commercial prototype that will be developed with this ERC POC grant will address a specific clinical application in the field of Cardiac Electrophysiology. As it will be designed to be manufactured as part of a quality system, it will be compelling for commercialization and for obtaining follow-on funding. The POC grant will be undertaken in close collaboration with Cardiac Electrophysiologists at Barts Hospital, and a medical device consultancy in the UK with  expertise in the development of ultrasound imaging probes. Clinician interviews will be conducted at a European clinical congre
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'New Approaches to Network Design'.

assistant: **Concept**

Networks pervade every aspect of nowadays life. This is one of the reasons why their design, management, and analysis is one of the most active areas of theoretical and empirical research in Computer Science and Operations Research. The main goal of this project is to increase our theoretical understanding of networks, with a special focus on faster exact exponential-time algorithms and more accurate polynomial-time approximation algorithms for NP-hard network design problems. We will consider classic, challenging open problems in the literature, as well as new, exciting problems arising from the applications. These problems will be addressed with the most advanced algorithmic and analytical tools, including our recently developed techniques: iterative randomized rounding, core detouring, and randomized dissection.A second, ambitious goal of this project is to stimulate the interaction and cross-fertilization between exact and approximation algorithms. This might open new research horizons.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The Formal Turn - The Emergence of Formalism in Twentieth-Century Thought' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

The philosophy of science and logic underwent a wide-ranging formal turn in the first half of the twentieth century. This shift is characterized by a new emphasis on formal methods and the adoption of a general formalist viewpoint towards the disciplines in question. The project will give a first interdisciplinary and comparative study of early contributions to formalism in twentieth-century thought. This general objective will be addressed in terms of three interrelated subprojects. The first subproject is historical in character and aims at a historical reconstruction of the emergence of formalist thinking in nineteenth-century mathematics and neo-Kantian epistemology. On the mathematical side, the project will retrace several methodological developments in geometry and algebra between 1860 and 1910 that contributed to a formalist conception of these fields. Regarding its philosophical roots, the focus will be on contributions to a formalist notion of scientific objectivity in the work of the Marburg school of neo-Kantianism (Hermann Cohen, Ernst Cassirer, Paul Natorp). The second subproject will give a comparative study of the formal turn in logic and logical empiricism between 1920 and 1940. This includes research on the foundations of mathematics and the formality of logic by members of the Göttingen school (David Hilbert, Paul Bernays, Gerhard Gentzen) as well as central contributions to a scientific formalism in logical empiricism (Rudolf Carnap, Moritz Schlick). The third subproject will analyze the philosophical implications of the formal turn for the subsequent shaping of these fields. The emergence of formalist thinking was closely related to the development of new theories of semantics in logic and philosophy. The aim will therefore be to connect the early c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'MONOMA: B2B Feasibility Study' (Monoma) targeting Horizon 2020.

assistant: **Abstract**

Monoma is a patent-pending cloud-based Software as a service (SaaS) solution integrating (i) modular, sensor based controllers (Hardware) and (ii) a platform with several therapy modules (Software), which (iii) collects and aggregates data insights to train people that have moderate-to-severe cases of Autism and other SEN. Monoma is designed to help users exercise regularly both cognitively and physically by triggering users’ creativity and engagement through games, music making and gamified training exercises. It is the only ergonomically accessible input device that is (i) fully customisable due to its bidirectional communication capacity, enabling new interaction possibilities and also adaptability to each end-user, (ii) that offers interoperability possibilities with other hardware and programmes enabling scalability and affordability, and (iii) collecting data insights to help therapists and educators assess the evolution of users’ capacities. The system has been developed by Filisia Interfaces, a UK-based company incorporated in 2014. Filisia’s customers are Therapist and Educators working in Special Schools, Therapy Centres and Care Homes. The company aims to penetrate its UK home market, scale up, and expand in Germany and the Netherlands, which together count for more than 649,342 educators and occupational, physical and music therapists who work in 160,000 institutions that cater for the needs of 3,441,400 people with SEN. Filisia aspires to become a key service provider, by making Monoma the main solution to cater for neuromuscular and cognitive impairments in the European and US markets, starting off with the UK, German and Dutch markets. By taking an average of only 2 solutions needed per centre, at its current pricing point (€450 for the device and €450 fo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Removal and Recovery of Heavy Metals from Waste Water by Sand Filters Inoculated with Metal Biosorbing or Bioprecipitating Bacteria' (1994-1998) under Fourth Framework.

assistant: **Objectives**

Objectives and content Large and small companies have many problems ensuring that the levels of contaminants in waste water are within regulations. Whether the source of this water is municipal or industrial, the major contaminant is often heavy metals. This is particular true of waste water resulting from the mining, metal processing and surface treatment industries, in which a physico-chemical process is employed to reduce the concentrations of metal in the water to that of a few ppm. To comply with new and future regulations concerning the environment a polishing technique to reduce these concentrations is proposed which will ensure cleaner European production technologies. The principles of such a polishing technique were established in a Brite Basic Research project. These principles, in conjunction with the special regeneration system of DynaSand filters, will be applied to the treatment of high volume wastewater at low cost. The sand filter medium will be inoculated with metal biosorbing and bioprecipitating bacteria which remove the trace metals from the water through a process of precipitation. The biosorption and bioprecipitation events were already studied in a former Basic Research Brite project. This technology will result in a continuously operating sand filter producing a metal containing biosludge. These metal loaded biosludges have the advantage that they are easily handled by the metal recycling industry compared to sludges from conventional technologies. In order to develop clean production technologies where the metals are recycled completely, with minimal production of unwanted by-products and waste, two metal processing companies (Union-Minière and Montanwerke Brixlegg) will study and optimise the recycling of the metal loaded sludge in their pyrom