RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Deciphering the dynamics and molecular mechanisms of APC/C activity in vitro and in live cells' (APCACTIVATION).

assistant: **Innovation**

The spindle assembly checkpoint (SAC) inhibits chromosome segregation and mitotic exit prior to biorientation of all chromosomes on the mitotic spindle by restraining the activity of the anaphase promoting complex or cyclosome (APC/C) towards Cyclin B1 and Securin. In contrast, other APC/C substrates like Cyclin A2 bypass this inhibition and are degraded in the presence of an active SAC. Despite its central role in mitotic progression, the molecular mechanisms activating the APC/C towards different substrates are poorly defined. Here, I present a research plan that aims to decipher the dynamics and molecular mechanisms of APC/C activity in live cells and in vitro. Specifically, I will establish an assay to quantify the spatial and temporal dynamics of APC/C-dependent ubiquitylation in live human cells by Foerster resonance energy transfer (FRET) between endogenously tagged Cyclin B1 and ubiquitin. In parallel, I will reconstitute the APC/C in vitro from recombinant proteins and quantify ubiquitylation activity of the reconstituted complex using fluorescently labelled substrates to assess the function of individual APC/C subunits, cofactors and posttranslational modifications. Together, the results obtained in live cells and in vitro will substantially advance our understanding of the molecular mechanisms that govern mitotic progression in human cells.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Industrialisation of High-Order Methods – A Top-Down Approach' (IDIHOM).

assistant: **Concept**

The proposed IDIHOM project is motivated by the increasing demand of the European aerospace industries to advance their CFD-aided design procedure and analysis by using accurate and fast numerical methods, so-called high-order methods. They will be assessed and improved in a top-down approach by utilising industrially relevant complex test cases, so-called application challenges in the general area of turbulent steady and unsteady aerodynamic flows, covering external and internal aerodynamics as well as aeroelastic and aeroacoustic applications. Thus, the major aim is to support the European aeronautics industry with proven-track method(s) delivering an increased predictive accuracy for complex flows and (by same accuracy) an alleviation of computational costs which will secure their global leadership. An enhancement of the complete “high-order methods’ suite” is envisaged, including the most relevant methods, Discontinuous Galerkin and Continuous Residual-Based methods, in combination with underlying technologies as high-order grid generation and adaptation, visualisation, and parallelisation. The IDIHOM project is a key-enabler for meeting the ACARE goals, as higher-order methods offer the potential of more accurate prediction and at the same time faster simulations.Main objectives: 1. Advance current high-order methods and apply them to complex industrial flows. 2. Demonstrate capabilities of high-order approaches in solving industrially relevant (challenging) applications and achieving synergy effects by applications to external and internal aerodynamics. 3. Demonstrate that high-order methods can be well applied to multi-disciplinary topics as there are aeroacoustics (noise reduction) and aeroelastics (reduced A/C weight, improved A/C safety). 4. Advance the Techno
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Top-quark physics with the atlas-muon spectrometer at lhc andcontribution to the construction and test of the first muon chamber - mdt - at the university of thessaloniki' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Research objectives and content The proposed project on one hand will exhaust physics topics for the start up of LHC, like Top-quark physics with the ATLAS-Muon Spectrometer and on the other will be a contribution to the construction and test of a prototype MDT chamber -Module zero- at the Nuclear Physics Laboratory of the University of Thessaloniki. It aims to do all the preparatory study on aspects of Top-quark physics so that with the start of run of LHC to be able to have results concerning the properties of the Top-quark and investigate aspects which need large statistics, like rare decays, CP violation etc. At the same time will be a contribution to the assembly and test of a prototype high precision muon tracking chamber (MDT), which will take place at the University of Thessaloniki in Greece. A temperature and humidity controlled laboratory will be set up at the University of Thessaloniki, and the complete procedure for assembling chambers of typical size lx2 m2, with mechanical precision in construction of the order of 10 microns will be established. The assembly method should be adequate for a serial production of over 100 chambers in the next few years. Finally, a test facility will be set up in order to verify the mechanical accuracy of the chambers, while their performance will be tested with cosmic ray muons. Training content (objective, benefit and expected impact) The proposed project will give the opportunity to the applicant, Dr. I.Vichou, to apply her knowledge and experience on | hardware and data acquisition and in particular on physics analysis with ATLAS specific software, in her country of origin. I The project at the University of Thessaloniki, in particular, will be a continuation of her project abroad. She will continue her | research on the s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'A precise and versatile nanotechnology with seed bio-stimulant microbial molecules to potentiate crop growth and immunization' in the context of a Horizon Europe call.

assistant: **Objectives**

Seed germination is the first step of a sequence of events that promote the transit of seeds from dormancy to vegetative growth. Therefore, it is a tightly regulated program that ensures further plant growth and survival in a supportive environment. The emergency provoked by continuous deterioration of the environment due to non-respectful crop management strategies and potentiated with climate change has increased the focus on this primordial stage of the plant growth as a primary target of strategies that help mitigating unsustainable issues. Beneficial microbes live in association with all plants, and we know how to take advantage of this benefit for the wealth of adult plants; however, little is known on their contribution to seed resilience and adaptation to a changing environment. This lack of knowledge may lead to unfeasible and weak bio-stimulant results undermining their credibility and entry into the market. Supported by findings of our deep investigation on the mutualistic interaction microbe-seed, we propose a proof of concept for a precise and customizable strategy based on the use of fengycin, a molecule produced by Bacillus cells in the interaction with seeds, and a fine-tuned nanotechnology platform to improve and increase the mobilization of nutrients of oil bodies containing seeds. We do expect a better adaptation of plantlets to the environment, major adult plant growth and immunization against microbial pathogens, and an average 50% reduction in the use of fertilizers and pesticides. Altogether our methodology should serve to improve the credibility of biological solutions as potent bio-stimulant of seed growth and thus potentiate their inclusion in sustainable programs of crop production and protection.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Galileo MEOSAR RLS Improvement for Better Civil Aviation Security', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Recent drama in civil aviation leading to losses of several aircrafts (AF447, MH370, etc…) have shown first an incapacity of quickly dispatching rescue means for potential survivals, and second, a surprising incapacity of determining the position of the aircrafts wreck, generating major researches expenses.This situation led to the creation of a joint RTCA/Eurocae working area in SC229/WG98 group; Its objective: define new solutions to cope with the current situation. It mirrors the ICAO recommendations from the Second High-Level Safety Conference (HLSC 2015) in Montreal. The conference raised key improvement areas and paved the way for the development of an integrated Global Aeronautical Distress and Safety System (GADSS) addressing all the flight phases. Based on these initiatives, a regulation will impose in-flight activations of aircraft S&R beacons for 2021.Aligned with GADSS perspectives and H2020 Galileo Topic 1, GRICAS proposes to develop a safety concept based on an innovative use of Galileo SAR service for a maximum rescue effectiveness. It includes the development of NG Beacons, innovative MEOLUT that optimizes the position accuracy even for high dynamic beacons, a new RLS employment concept, and associated  In-flight beacon activations triggers when detecting abnormal flight situations. Based on key regulation S&R players within the consortium (CNES, BEA, DGAC), GRICAS is a unique opportunity to bring to the fore one of the essential Galileo differentiator compared to other GNSS, e.g. a rich S&R service with a unique Return link service, decisively contributing to the aviation safety. The technological developments are supported by rich In-flight experimentations and demonstrations, relayed by a strategic dissemination plan irrigating the aeronautical regula
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Dynamics and structural rearrangements of colloidal suspensions under oscillatory shear strain by diffusing wave spectroscopy' (1994-1998).

assistant: **Concept**

Research objectives and content In this project we will investigate the dynamics and structural rearrangements of glassy colloidal suspensions subjected to a periodic shear strain. The motion of the colloidal particles will be studied for low oscillatory shear strains, where an elastic response of the suspension is expected, as well as for high shear strains, where the suspension is expected to yield. The question of the reversibility of the colloidal motion, and thus the degree of rearrangement of the suspension below and above the yield stress, will be addressed. Probing the colloidal motion under these conditions will enhance our understanding of the mechanisms of yielding in such amorphous systems. The main experimental technique to be employed is Diffusing Wave Spectroscopy (DWS) which, in highly turbid samples, can probe much more local scale dynamics than conventional Dynamic Light Scattering (DLS). DWS will be used to probe the motion of the particles induced by the strain and to detect the reversibility of the motion through echoes in the intensity correlation function of multiply scattered light (see, e.g., Hebraud et al., Phys. Rev. Lett. 78, 4657, 1997). As supplementary techniques we will use DLS under oscillatory shear strain for single scattering systems, as well as Two Colour Dynamic Ligh Scattering (TCDLS) and DWS of quiescent multiply scattering colloidal suspensions. Training content (objective, benefit and expected impact) Training will be received in the properties of colloidal systems and in several specialized and modern light scattering methods. As part of a large group pursuing theory and simulation as well as experiment, the applicant will also be exposed a broad range of other topics in the general area of soft condensed matter. As noted under
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Establishing of support network for promotion of innovative SMEs development of ELectronic and INformation technology branches in the REGions of LATvia.'.

assistant: **Objectives**

The goal of project is to create a strong support network for development of innovative SME sector of Electronic industry in Latvia regions in order to provide of information and advance on Community RTD activities and to promote the new technologies as well as industrial co-operation on a base of existing potential of regional universities and Enterprise support centres (ESC) network in Latvia. The BIC Noord-Nederland and ASTER agency (Italy) together with BIC of Latvian electronic Industry will create informative tools (data bases) and set-up a transnational support network in electronic and IT branches as well as will provide for selected regional innovative SMEs following services: identification of their technological needs, partner search, training for business development and international co-operation, organising of study tours to the European BICs.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Climate Impact Research & Response Coordination for a Larger Europe - 2nd Generation ERA-Net -Science meets Policy' (CIRCLE-2) targeting Seventh Framework.

assistant: **Abstract**

Climate Change is one of the most important issues facing the world in the 21st century and challenges all four (ecological, economical, social and cultural) dimensions of sustainable development. Europe takes a leading role in the necessary response to these challenges. Severe impacts are unavoidable and European adaptation strategies must be supported by a coherent base of knowledge on its key vulnerabilities and response options. Such a base can only be generated by European, national and regional policy-relevant research. It is CIRCLE-2 ERA-Net prime objective to contribute to those efforts by aligning and networking national and regional research funding and managing organisations as well as their respective programmes. CIRCLE-2 will support a common research agenda and share good practices on adaptation with national and European decision makers, thus contributing to the envisaged EU Clearing House on Climate Change Impacts Vulnerability and Adaptation (CCIVA). CIRCLE-2 (CSA-CA) builds on the experience of previous coordinating and support actions (i.e. CIRCLE CA and SSA) and will develop its activities through a now enlarged network of 23 countries and 3 regions. A flexible work plan will LEAD the consortium to identify common policy-relevant CCIVA research needs. Those needs will serve to DESIGN a joint research agenda and deepen the networking and cooperation activities of the consortium. CIRCLE-2 will FUND transnational joint research initiatives including joint calls for projects on CCIVA. The outcomes of these initiatives and projects will provide the consortium with an updated knowledge base on European, National and Regional CCIVA research and CIRCLE-2 will SHARE this knowledge base with decision-makers at all relevant scales. CIRCLE-2 will thus contribute
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Water use and carbon budget associated with adaptation and competition of C3 and C4 grasses during drought stress' under Seventh Framework.

assistant: **Concept**

Water availability is a major abiotic factor limiting plant growth and productivity. Grasses are major contributors to global primary productivity. Many C3 and C4 grass species are intolerant to drought stress and are often limited by water availability in terms of their distribution and productivity. However, Some C3 and C4 grass species, such as Festuca arundinaccea (C3) and Cynodon dactylon (C4) are adapted to a wide range of climatic zones in Israel, with an annual rainfall of 30 to 1000 mm.  The overall goal of the proposed research is to examine mechanisms of adaptation to drought stress of dryland C3 and C4 grasses. The specific objectives of the study are: 1) to compare drought tolerance between ecotypes of C3 and C4 grass species collected from different climatic zones; 2) to determine mechanisms regulating drought survival of dryland perennial C3, C4 and C3-C4 intermediate grasses in terms of water use and carbon budget and to link between water and carbon relations;3) to create a wide germplasm bank of drought-tolerant grasses for future research and breeding;.  C3, C4 and C3-C4 intermediate grasses will be collected from a wide range of climatic zones and studied for drought tolerance. A number of physiological parameters, including growth rate and photosynthetic rate, will be measured and compared for the evaluation of drought adaptability. Carbon metabolism and water use characteristics will be examined to determine drought tolerance strategies of dryland C3 and C4 grass species. Carbon benefits and costs associated with water relations will be assessed for different grass species adapted to different climatic conditions.  Examination of C3 and C4 mechanisms that link water use and carbon expenditure will provide further insights into plant adaptation to l
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Nonsmooth Contact Dynamics' under Horizon 2020.

assistant: **Concept**

The overall aim of the project is to develop a joint training and cutting-edge research program based on state-of-the-art technologies that will strengthen the research partnership among ten institutions in eight countries on five continents: Poland, France, Romania, Spain, Argentina, Australia, P.R. China, USA in the areas of common research interest, nonsmooth contact mechanics, inclusions in Banach spaces, optimal control, and computational algorithms for nonsmooth problems. The estimated duration of the project is 48 months. The aim will be achieved through short- and long-term periods of staff exchange between partners in Europe, United States, South America, Australia and China, and networking activities between the institutions. The ultimate goal of the project is to achieve more rapid progress in advancing current knowledge and concepts through combined endeavour leading to two book monographs and joint-author high citation index publications. In this way, we will establish a long-term research cooperation among ten institutions based on active technology and scientific knowledge application and transfer. The scientific aim of the research exchange is to develop new and non-standard mathematical and numerical tools directly motivated by the needs of the analysis of various classes of contact problems which are of fundamental importance in technology, industry and real engineering applications. A throughout research of contact processes will not only allow to gain an improved fundamental understanding of contact mechanics but also advance current knowledge that can ultimately be used for the improvement of industrial applications of economic benefits. Trainings, meeting, seminars, workshop and conference are being planned for this research proposal in order to sh
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Completion of the Arbre Plant with the Typhoon Gas Turbine' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

The primary objective of the project is to demonstrate that BIGCC Technology has reached industrial reliability and can therefore be scaled up and replicated internationally. This will be achieved by demonstrating conclusively that:- short rotation forestry (SFR) can be successfully established in the EU under market conditions to produce the renewable fuel resource for power plants;- fluidizes BED gasification of biomass followed by catalytic cracking of tars has been scaled up to industrial size operations successfully;- The typhoon gas turbine has been successfully modified to burn low calorific value fuel gases and now commercial guarantees can be provided and the integration of the combined cycle with the gasification plant offers the possibility of CHP operation. The project also aims to demonstrate operational reliability and economic viability with very high overall efficiency and very low environmental impact.