RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'from SPArsity to DEep learning'.

assistant: **Concept**

Lately, deep learning (DL) has become one of the most powerful machine learning tools with ground-breaking results in computer vision, signal & image processing, language processing, and many other domains. However, one of its main deficiencies is the lack of theoretical foundation. While some theory has been developed, it is widely agreed that DL is not well-understood yet.A proper understanding of the learning mechanism and architecture is very likely to broaden the great success to new fields and applications. In particular, it has the promise of improving DL performance in the unsupervised regime and on regression tasks, where it is currently lagging behind its otherwise spectacular success demonstrated in massively-supervised classification problems.A somewhat related and popular data model is based on sparse-representations. It led to cutting-edge methods in various fields such as medical imaging, computer vision and signal & image processing. Its success can be largely attributed to its well-established theoretical foundation, which boosted the development of its various ramifications. Recent work suggests a close relationship between this model and DL, although this bridge is not fully clear nor developed.This project revolves around the use of sparsity with DL. It aims at bridging the fundamental gap in the theory of DL using tools applied in sparsity, highlighting the role of structure in data as the foundation for elucidating the success of DL. It also aims at using efficient DL methods to improve the solution of problems using sparse models. Moreover, this project pursues a unified theoretical framework merging sparsity with DL, in particular migrating powerful unsupervised learning concepts from the realm of sparsity to that of DL. A successful marriage bet
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Old anD Young Star clusterS tracing Evolution and assemblY'.

assistant: **Innovation**

In the standard framework of galaxy evolution, galaxies form in a two-phase scenario that comprises a quasi-monolithic formation of an in-situ population, followed by the accretion of of lower-mass galaxies. As these merger processes significantly alter the morphology and kinematic state of a galaxy, reconstructing the assembly history of galaxies is a challenging but fundamental task to understand galaxy evolution. In that context, dense star clusters such as globular clusters, young massive clusters, and nuclear star clusters, that still contain  information of their birthplace and subsequent evolution imprinted in their stellar population are potentially powerful tracers of galaxy assembly. While ancient globular clusters are fossil records of early star formation and galaxy accretion, young massive star clusters trace recent star formation episodes and interactions, and nuclear star clusters provide an unique window into the evolution of a galaxy's central region. The ODYSSEY action aims to fully unlock the potential of these star clusters as tracers of galaxy evolution by employing a comprehensive framework that combines for the first time the insights provided by globular clusters, young massive clusters and nuclear clusters. To achieve this, ODYSSEY has two main objectives: 1) exploring the complex interplay between galaxies and the star clusters they host and b) constructing a flexible semi-analytical model that constrains the assembly history of individual galaxies from their star clusters. The proposed research programme will greatly advance our understanding of the mechanisms that shape star clusters and of how they are connected to the evolution of their host galaxies, while at the same time providing a new methodology of how galaxy evolution can be studied.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Advances in aErosol Retrievals and Impacts on South america' under Horizon Europe.

assistant: **Concept**

AERIS aims to build an international, cross-sectoral network to advance atmospheric sciences by improving vertically-resolved atmospheric characterization techniques, including near-surface regions. The project unites European academic and commercial institutions with North and South American partners (LALINET). AERIS enhances measurement techniques, connects international observation programs, and creates opportunities for early warning systems, business innovation, and job creation. The main objective is to advance retrieval capabilities for biogenic and non-biogenic aerosols over South America, enabling data with applications in health, hydrology, air quality, and climate. This will support a regional early warning system with global implications, benefiting aviation, biodiversity, and space mission validation. Specific goals include: (1) Implementing quality assurance and calibration for vertically resolved and near-surface measurements; (2) Optimizing inversion algorithms for aerosol property retrievals; (3) Enhancing synergies between instruments to improve spatial and temporal data; (4) Developing predictive models linking aerosols to health impacts; and (5) Investigating aerosol-induced cloud nucleation and its effects on the hydrological cycle.South America faces critical atmospheric challenges with global consequences. Limited infrastructure and monitoring networks hinder accurate data collection and climate modeling, weakening public policies and international cooperation. AERIS addresses these challenges by integrating high-quality, vertically resolved atmospheric data with near-surface imagery, advancing aerosol characterization in South America. This unique database will strengthen regional and global atmospheric science. To achieve these goals, AERIS incl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'DNA modules as communicators in tumor immunomodulation' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Our goal is to develop all-DNA structures (protocells) that can act as modulators of the immune system and, in particular, of signaling processes in oncology. Molecular DNA switches that interact with cells via aptamers have been developed and used for drug delivery, cell imaging, and potential therapies. However, there are several advantages of incorporating these swithces into protocells, such as the protection of these circuits against degradation, the ability to create gradients and as a delviery method for in vivo application. DNA protocells that (i) have the ability to recognize proteins and small molecules and (ii) amplify signals and generate output that alters cell physiology have not yet been developed. Realizing these structures requires filling a gap in our knowledge of how of how aptamer reactions network in confinement. We anticipate that by filling these gaps in our knowledge, we will be able to produce a pure DNA protocell that can harbor aptamer-based response networks for modulation of intercelullar communication in the tumor microenvironment.


**Keywords:** DNA protocell, aptamer, tumor microenvironment, self-assembly, DNA computing, nucleic acids, cell communication
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The 20th General Conference of the Condensed Matter Division of European Physical Society' to be submitted under Sixth Framework.

assistant: **Abstract**

The Charles University in Prague will organise the 20th General Conference of the Condensed Matter Division of European Physical Society (CMD 20) in collaboration with the Czech Physical Society and the Institute of Physics ASCR. The CMD20, which will be held in the Prague Congress Center on July 19-23, 2004 (see: cmd.karlov.mff.cuni.cz/CMD/), provides a forum for presentation of research work across the full range of condensed matter physics.The foreseen composition of the audience and the identification of the speakers will guarantee a high Community added value. The CMD20 Program Committee will select excellent speakers able to highlight particular achievements. The key subjects will be chosen, in which is a strong interest to contribute to their uptake in Europe. The format of the meeting will be similar to the most recent ones in the series, held in Brighton, 2002 and in Montreux, 2000, each of which attracted about 1300 participants. The conference program will include plenary talks, up to 32 focused sessions with invited speakers, up to 32 mini-colloquia and ample space for poster sessions. The mini-colloquia offer space for discussing mainly novel topics, while the focused sessions will be devoted to selected important areas of condensed matter physics. The conference will be preceded by a tutorial Student day.Since CMDs have been so far organised predominantly in west European countries we expect that besides the traditional auditorium the CMD20 will attract a considerable number of participants from east European" countries. Particular attention will be paid to receive sufficient audience formed by young scientists and student to enable passing the advances achieved in the EU Member and Associated States, as well as, elsewhere in the World on to researchers in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Reactions That Translate mRNA into Drug-like Molecules' (TRIGGDRUG).

assistant: **Innovation**

How could a molecular cancer therapy look like in 2040? In cancer, gene expression is deregulated due to amplification, mutation and translocation of genes. Next generation RNA sequencing provides us with the opportunity to identify the number and identity of the gene products aberrantly expressed in a patient. But do we have methods that take advantage of the personalized sequence data? In this research project we propose the idea to use the RNA molecules expressed upon disease-type gene expression as instructors for the chemical synthesis of drug-like molecules that cure the disease. Accordingly, drug-like molecules would only be formed in those cells that express the disease-specific RNA molecules. Such a personalized molecular therapy would eliminate side effects caused by unwanted perturbation of healthy cells. The idea to use cellular RNA molecules as triggers for drug synthesis requires methods that couple RNA recognition with a change of chemical reactivity. Reactive molecules must be able to “read” and “translate” the sequence of a RNA molecule into a drug-like output. We will develop mRNA-triggered reactions that i) proceed with turnover in template to cope with low mRNA copy numbers and ii) allow the single-step synthesis of highly active drug-like molecules to address deregulated protein targets inside cancer cells. To achieve this aim, we will advance chemical acyl transfer and alkylidene transfer reactions. The reactions on disease-specific mRNA will form peptides/peptidomimetics/small molecule-based kinase inhibitors which will induce apoptosis in cancer cells. We will target validated drug targets. Synergy between the nucleic acid and protein worlds will be harnessed. Furthermore, we will develop a RNA-promoted reaction with turnover beyond product inhib
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'COMPUTER AIDED ENVIRONMENTAL MANAGMENT INFORMATION SYSTEMS - NEW ENVIRONMENTAL TOOLS AND STANDARDS' (CAEMIS-NETS).

assistant: **Concept**

The CAEMIS-NETS project highlighted the importance of auditable systems based approaches to environmental management, particularly as exemplified in the EU Eco-Managment and Audit Schemes (EMAS). It introduced an innovative computer based tool which supports the design, implementation and development of environmental management systems in industry which could develop into a standardised EU-Wide acknowledged systems standard.The objective of the project was to enhance dissemination of the methodologies, best practice and results emerging from Caemis into key industrial domains and across various regulatory environments and member states. This required materials in different languages and events in different member states in order to disseminate the information widely. The original team members were complemented by a participant from Imperial College.This project provided nearly EURO 200,000 to enable the participants to disseminate information about the previous Caemis project and to extend its implementation into new sectors. A large number of activities were undertaken including conferences, leaflets, CD Roms etc, which were professionally produced. However, there did not appear to be a great demand for this material and although large numbers of items were distributed, it is not clear what impact has been achieved e.g. how many organisations are now making use of the software. Some new knowledge was obtained / exchanged between participants including an assessment of the EMAS and ISO 14001 requirements and the provisions of Caemis.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Historical Small Smart City Protocol for integrated interventions.' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Over the last decade, the urban conservation challenge has grown critical due to rapid urbanization and the resulting growth and transformation of cities worldwide. Conserving historic urban environments is currently one of the most universally urgent and challenging cultural heritage conservation issues. The research project ""Hismacity-pro"" aims to develop a detailed protocol of multidisciplinary integrated interventions targeted at the recovery and revitalization of small historic centers by enabling smart city services, in order to improve the quality of life in these settlements, which are usually confined within marginal areas, far from the biggest cities. The protocol will be able to be replicated in other southern European towns with the same needs. At the moment,  Italian small centers haven’t been rigorously mapped and requalified and local policies aimed at their recovery are quite absent, while the Italian Agency for Territorial Cohesion has recently set up a central policy for their valorisation. The protocol will be adoptable by this strategy and will convey an operative tool of guidance for municipalities in peripheral areas on policy management, in central Italy and Catalonia (Spain). The research will be grounded in an holistic management of sites and their surrounding context and will encourage a considerable increase in the competitiveness of small historic centers, as well as their conservation and economic sustainable growth. The project will assess the state of information available to practitioners and identify unmet needs in the conservation of historic cities and urban settlements. It will also try to find a response to how small historic towns can use local assets to revitalize their economy, and the logic of turning problems into resources wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'European Social Catalyst Fund' (ESCF), addressing dissemination and exploitation.

assistant: **Impact**

As societies evolve and the challenges they face take on old and new form and expression, it is vital that governments and their partners find ways to best serve their citizens. As governments’ management of and impact on the most vulnerable in society is increasingly in the spotlight, innovation in social services delivery is critically needed. This brings into sharp focus why and how a European Social Catalyst Fund (ESCF) can be a key stimulus factor in the delivery of socially innovative initiatives that have the capacity to scale to make a real impact at national and international levels. This proposal intends to establish the ESCF and is based on practical social innovation experience garnered by the Consortium, working with philanthropy and government to bring about sustainable improvements for service users, across a range of social services. The ESCF is designed to bring together public and private resources in a range of collaborations that focuses on the role that philanthropy and social impact finance can play in working with governments to help re-focus public spending in a more cost-effective direction in the interest of EU citizens. Innovations in social services will be identified and supported through the ESCF to develop robust implementation plans to enable scaling. The implementation plans funded from the call will be transferrable across EU countries, subject to tailoring aspects to fit local cultural and operational environments. The Consortium has demonstrated experience of embracing the catalytic role that private finance can play in creating innovations and offers a highly viable route to achieving scale by the public sector. Learnings from this process will be utilised to design a further phase of the ESCF which will focus on supporting the imple
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'REFURBISHMENT AND ADDITIVE MANUFACTURING ACCOMPLISHED BY KINETIC DEPOSITION'.

assistant: **Concept**

Ambitious goals of the European Green Deal call for new sustainable and material-efficient manufacturing technologies that can reduce energy and raw material consumption; this objective can be upheld by extending the product life via optimized production methods, recovering product performance through refurbishing, and even improving its functions beyond design by remanufacturing. These are the overarching objectives of RE-MAKE that considers cold spray (CS), a solid-state metal powder deposition technique, as the key for a new route to additive manufacturing (AM), repair and remanufacturing. Thanks to its exceptional deposition efficiency, high build-up rate, limited energy consumption, and flexibility of material choice, CS is an ideal candidate for the EU Circular Economy Action Plan. However, currently, there are multiple scientific and industrial gaps, paired with poor awareness about CS’s potential due to the lack of qualified engineers and scientists, that impede the full exploitation of CS.  RE-MAKE is planned to establish CS as a unique sustainable and scalable tool for AM, remanufacturing and upcycling, paving the path to a green and efficient sustainable industrial development. This ambitious goal will be achieved by training highly qualified doctoral candidates (DCs) through advanced transversal and inter-sectoral training. The wide-ranging hard and soft skills the DCs will gain enable them to embark on tackling scientific and technological challenges with a practical perspective. Creating a network of leading European research and industrial partners, all working at the cutting edge of CS, will expose DCs to a holistic training with access to a wealth of expertise and a rare multidisciplinary environment. RE-MAKE will endow a first cohort of these essential