RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Harnessing comparative genomics for trait specific synthetic plant symbionts - SYNBIONT' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Climate change is undermining global food security through intensifying droughts, heat waves, and plant diseases. Microbial symbionts are increasingly recognized as key allies for climate-resilient agriculture, yet current approaches based on synthetic communities (SynComs) often fail under field conditions due to ecological instability. In parallel, comparative genomics has generated vast datasets linking host- and trait-associations for tens of thousands of bacterial genes, resources that remain largely untapped for rational symbiont design.The SYNBIONT project will harness these datasets to identify “trait cassettes”, gene clusters enriched in plant-associated bacteria and correlated with enhanced resilience to (a)biotic stresses. These cassettes will be integrated into Pseudomonas putida KT2440 (P. putida), followed by controlled Arabidopsis thaliana (A. thaliana) experiments under defined stress regimes. Validated resilience-associated genes will be combined into P. putida carrying 3-5 cassettes, engineered to cope with multiple simultaneous stresses, and benchmarked against traditional SynComs.Integrated phenotypic, transcriptional, metabolic, and physiological analyses will establish causal links between trait cassettes and plant resilience. This approach shifts the field from correlative observations to mechanism-driven, programmable symbionts. Key deliverables include: (i) a validated “PlantFit” atlas of trait-specific genes for stress resilience, (ii) a library of modular, ready-to-use cassettes for rapid deployment, and (iii) engineered P. putida chassis strains for mechanistic studies and translational agriculture.My expertise in synthetic biology and functional genomics, combined with the host lab’s strengths in comparative genomics and plant-microbe experi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Platform for Automatic, Normalized Annotation and Cost-Effective Acquisition of Language Resources for Human Language Technologies'.

assistant: **Concept**

A strategic challenge for Europe in today's globalised economy is to overcome language barriers through technological means. In particular, Machine Translation systems are expected to have a significant impact in the managing of multilingualism in Europe.PANACEA is facing the most critical aspect for Machine Translation to produce this expected impact in Europe: the called resources bottleneck. MT technologies are in themselves language independent, but they are inherently tied to the availability of language dependent resources.PANACEA will be an integrated machinery for the production of Language Resources (LR) designed in line with new paradigms of software development that rely on a future internet made as a global and open service delivery platform.  PANACEA is designed as a dedicated workflow manager for the composition of an open number of systems based on combinations of different webservices. While webservices considered by the project will be limited in number, the proposed way of assembling them in workflow chains using metadata and standards will make of PANACEA and open and interoperable platform also capable of integrating new components as needed for the production of new LR.PANACEA is to shape a LR factory that step by step covers the automation of all the stages involved in the acquisition, production, updating and maintenance of LR required by MT systems and in the time required. Automation will significantly cut down the economic and temporal costs of the supply of LR. This reduction of costs and time are the only way to guarantee the massive supply of LR that Machine Translation and other Language Technologies will be demanding in the multilingual Europe. Evaluation in an industrial scenario will be the proof of concept of the benefits offered by PAN
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Effector discovery and validation of Puccinia striiformis sp. f. tritici, a wheat pathogen""' (RUST-SAFE).

assistant: **Concept**

Effectors are used by pathogens as weapons against their hosts. Puccunia striiformis f. sp. tritici (PST) the causal agent of yellow rust, is able to produce and secrete these proteins inside its host, wheat. This disease is responsible of epidemics around the world, including Europe. Even more, two new and aggressive strains of this pathogen may constitute the most expansive and accelerated spread ever of a wheat disease. The discovery and characterization of new effectors of yellow rust will open the door to new and sustainable resistance strategies, which is in accordance to European Union objective of sustainable management of crop pest diseases, that has been founded through the 6th and 7th framework programmes.I propose the use of state-of-the-art sequencing technology to obtain putative fungal sequences from wheat infected tissues with four PST isolates, and a bioinformatics approach to search, identify, classify and select from these sequences which correspond to putative effectors. Afterwards I propose an innovative and elegant experiment to test whether they are real effectors, monitoring the collapse of effector-transfected protoplasts as a result of gene-for-gene recognition resistance mechanism.The John Innes Centre, where this project will be carried out, and the nearby The Sainsbury’s Laboratory and Norwich Research Park compose a cluster of excellence and expertise in plant biology and microbiology that have been awarded by these EU programmes. I will take advantage of the multidisciplinary approach of the proposal and of the scientific expertise and training experience of the host to expand my knowledge and boost my career to reach a position of independent researcher.Finally, the proposed IEF would make a significant contribution to ERA, sharing knowle
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Brain controlled aircraft flight using multiple feedback mechanisms' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Several studies have revealed that the activity of neurons is sufficiently capable of providing enough data to enable the control of an electronic device using solely signals provided by the brain. Project BRAINFLIGHT proposes the application of this kind of control in the world of aircraft, to enable people to control aircraft using only neural signals emitted from their brain. This kind of approach constitutes a novel concept for the control of these platforms, and was until recently only conceived as science fiction.The goal of project BRAINFLIGHT is to create a novel approach to aircraft control, and to assess the performance of this concept. This project is mainly focused on investigating what are the best approaches that allow fast learning to control an aircraft using brain signals, while allowing pilots to multitask. Project BRAINFLIGHT will test an innovative approach for brain control of flight, which takes advantage of the amazing ability that the brain has of learning to use novel tools using operant conditioning. The project will test how the use of this approach, as well as different feedback mechanisms for the pilot (visual and/or tactile), will affect learning and performance compared to conventional control. The project will also test the ability of pilots to multi-task using brain control by performing experiments where integration and interference between multimodal signals are investigated. In addition, if the control described above does not allow control of many degrees of freedom or allow for multitasking, we will test an alternative approach in which pilots will use their neural activity to select particular tactile sensory stimuli in order to control the aircraft.Finally, after the best approach and parameters are selected, the functionality of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'VISIT - Vertically Integrated Systems for Information Transfer' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The proposed STREP focuses on strategic, high-value photonic components and subsystems for scalable economic broadband access and local area networks. The central objective is research on, development, test and exploitation of system-enabling optical transmitters having a completely novel design and/or largely improved functionality as compared to the state of the art.Three key design and performance advancements will overcome limitations of present devices to become future-proof drivers of the European photonics industry:A novel nanophotonic approach of vertical integration of an electro-optic reflectance modulator and a laser implemented into:a)\tVertically Cavity Surface Emitting Lasers based on  Electro-Optically Modulated Bragg Reflector andb)\tEdge emitters based on Electro-Optically Modulated Tilted Wave Lasersconstituting the basis for future access, local (LAN) and storage area (SAN) networks capable to speeds well beyond 40Gb/s.c)\tFor applications at 16-40 Gb/s (Fibre Channel, InfiniBand standards) a new generation of directly-modulated VCSELs will be developed to bridge the intermediate bandwidth demand in the fastest possible time frame.Epitaxial growth of these structures, processing and design of high-frequency modules will be challenging and demand detailed modelling. The wavelength ranges to be covered are 850 nm, 980 nm, and 1.3 µm. While 850 nm (LAN, SAN) and 1300 nm (LAN, Access Networks) ranges are standard for applications, 980 nm devices may play an important role for very short links.Low power driver circuitry, as well as system integration and performance requirements will be also dealt with within this project. Upon completion a full supply chain from production of epitaxial wafers to test beds for measurements and prototype systems will be est
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Empowering Citizens to TrAnsform European PubLic Administrations', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

High quality public services constitute the backbone of citizens’ social welfare and are also essential to a region’s competitiveness and business entrepreneurship. Delivery of high quality public services is instrumental so that society and its economy can function. Despite this, the future provision of public services faces significant social challenges, as stated in H2020 “Understanding Europe - Promoting The European Public And Cultural Space”. Key challenges include those due to demographic change and others, related to the EU´s continued search for a model of advanced economic and social development compatible with demands for competition in a globalized economy. All of these longer-term challenges mean that public service provision must be reinforced on the basis of more and better innovation, and greater efficiency and productivity.CITADEL will create an ecosystem of best practices, tools and recommendations to transform Public Administrations (PAs) via an inclusive approach in order to provide stakeholders with more efficient, inclusive and citizen-centric services. The CITADEL ecosystem will allow PAs to use what they already know and new data to implement what really matters to citizens in order to shape and co-create more efficient and inclusive public services. CITADEL innovates by using ICTs to find out why citizens stop using public services, and use this information to readjust provision to bring them back in. Also, it identifies why citizens are not using a given public service (due to affordability, accessibility, lack of knowledge, embarrassment, lack of interest, etc.) and, where appropriate, use this information to make public services more attractive, so they start using the services. CITADEL will be implemented and validated in four use cases in L
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'MUltiscale, Multimodal and Multidimensional imaging for EngineeRING' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The overarching goal of MUMMERING is to create a research tool that encompasses the wealth of new 3D imaging mo-dalities that are surging forward for applications in materials engineering, and to create a doctoral programme that trains 15 early stage researchers (ESRs) in this tool. This is urgently needed to prevent that massive amounts of valuable tomogra-phy data ends on a virtual scrapheap. The challenge of handling and analysing terabytes of 3D data is already limiting the level of scientific insight that is extracted from many data sets. With faster acquisition times and multidimensional modali-ties, these challenges will soon scale to the petabyte regime. To meet this challenge, we will create an open access, open source platform that transparently and efficiently handles the complete workflow from data acquisition, over reconstruction and segmentation to physical modelling, including temporal models, i.e. 3D “movies”. We consider it essential to reach this final step without compromising scientific standards if 3D imaging is to become a pervasive research tool in the visions for Industry 4.0.The 15 ESRs will be enrolled in an intensive network-wide doctoral training programme that covers all aspects of 3D imag-ing and will benefit from a varied track of intersectoral secondments that will challenge and broaden their scope and ap-proach to research. The ESRs will exit the MUMMERING network as highly attractive and employable PhDs with a practical and qualified take on industrial research.


**Keywords:** Tomography, 3D, 4D Imaging,  High Performance Computing, Electron Microscopy, Synchrotron Radiation, X-rays, CT
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Micro-RNAs of neutrophils in renal ANCA-associated vasculitis' under Horizon 2020.

assistant: **Concept**

Activation of neutrophils by ANCA (“Anti-Neutrophil Cytoplasm Antibodies”) and subsequent endothelial cell (EC) damage is the main feature of ANCA-associated vasculitis (AAV). There is no specific treatment for AAV to date and 25% of patients evolve towards end-stage renal disease requiring dialysis and renal transplantation. While accumulating data indicate that miRNAs control major biological responses in various cell types including EC and neutrophils and are involved in the pathophysiology of several diseases, their role in AAV has been virtually unexplored. In addition, recent studies have shown that ANCA-activated neutrophils can induce EC damage through the release of microparticles, but while many studies have revealed a critical role for miRNAs secreted within microparticles in intracellular crosstalks, there is no data so far on the role of miRNAs in this process. Here, we propose to identify miRNAs deregulated in neutrophils exposed to ANCA and released in microparticles that promote EC damage in AAV. These miRNAs will be identified using TaqMan Low Density Arrays in ANCA-stimulated neutrophils in vitro and in the microparticles they release, as well as in neutrophils from patients with AAV. To assess whether these miRNAs could be used as biomarkers, their expression will also be analyzed in plasma and urine samples from AAV patients, and correlated with severity and outcome of the disease. The transfer of neutrophil-secreted miRNAs to EC will be assessed in vitro, and the function of these miRNAs in the regulation of EC responses (activation, angiogenesis) will be studied in various functional assays. While miRNAs are emerging as new therapeutic tools for several diseases, this translational study will provide the first data regarding the expression and func
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Nature-inspired Cryopreservation Systems using Natural Deep Eutectic Systems' (CryoDES) under Horizon Europe.

assistant: **Objectives**

Cell therapies are foreseen as the next generation therapeutics for some of the chronic diseases with highest global economic and social burden. The market for human cell therapies has been estimated to be 8 B€ in 2021 with an expected annual growth rate of 26% until 2028. The key aspect for the success of a cell therapy is the preservation of cells. Currently, cells must be cryopreserved using a cryoprotectant agent (CPA) at -196ºC, in a liquid nitrogen tank. The gold standard CPA is a chemical organic compound, dimethyl sulfoxide (DMSO) highly toxic. Despite this it has high success rates and continues to be the industry gold standard CPA. Inspired by Nature, CryoDES was developed. CryoDES is a cryoprotectant agent, non-toxic and composed of generally regarded as safe components. These systems have proven to be able to replace the gold standard CPA, presenting the same or better performance indicators. One of the major advantages of these systems is the fact that it allows the storage of cells at -20 ºC, in a conventional freezer, vastly outperforming DMSO. The CryoDES team is composed of researchers and entrepreneurs who are passionate about science. Together, the CryoDES team has been working on this technology for the four years and envisage now to bring it to the next level towards a commercialization strategy. To achieve this, in this PoC the team intends to perform technical feasibility studies of the product; evaluate the commercial value of the product; perform a market assessment study and draft the plan for commercialization.. Albeit projects and results related to Life Sciences and Biopharmaceuticals require time to become a reality due to the need of the respective pre-clinical and clinical trials, this PoC Action will have as immediate outcome the creatio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Study of the Impacts of the Transport RTD Programme' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

DGVII has commissioned almost 300 Transport RTD projects under the auspices of the Fourth Framework Programme. In order to assist in the synthesis and transition from FPIV to FPV, DGVII wishes to commission a focused programme of research that will:* develop an assessment method to qualify and, as far as possible, quantify the benefits of research;* appraise the value and benefits of the programme; and, through this* draw conclusions on the broad level of effectiveness of the research tasks.From this it will be possible to refine the FPV programme and tasks, by identification of those areas where significant developments and break throughs have been made and those where further preliminary development work is required. In some aspects the study appraisal will be carried out at the strategic programme level, particularly in regard to the opinions of policy makers and policy implementers. However, in certain respects, especially regarding technical issues, the appraisal will only be informative at a detailed project level. It is not feasible to examine the whole Programme at this level of detail, and therefore Programme sampling will be carried out. Working within the constraints of this study, the sample of projects cannot strictly be considered a representative sample of projects within the Programme. Instead, the findings of the more detailed study will be used to enhance the understanding of the findings Programme wide.The projects will be selected bearing in mind that they are part of a Programme, and have inter-dependent relationships with other projects. It is not meaningful to consider a project in total isolation. Instead it may be considered in the context of adding value to impacts of a group of associated projects. %