RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Super-Resolving Quantum Imaging and Detection' under Horizon 2020.

assistant: **Concept**

Imaging and remote sensing protocols in the classical domain are fundamentally limited by the diffraction limit and detection noise. To move beyond these boundaries photonic quantum technologies provide new paradigms for achieving unprecedented sensing performance. The SURQUID project will achieve both super-resolution below the Rayleigh diffraction limit and super-sensitivity below the shot noise limit for light detection and ranging (lidar) applications. Using quantum homodyne detection (QHD) combined with non-classical illumination using entangled coherent states (ECS) we will realize a quantum lidar system for multi-scale quantum imaging with unparalleled accuracy and precision. We will implement a long-term stable QHD system by integrating multiple superconducting single photon detectors (SNSPDs) in nanophotonic circuits. Operation in the telecommunication spectral window, where atmospheric transparency is high, will enable  remote quantum imaging on a logarithmic length scale from 100 mm to 100 km distances. Waveguide-integrated SNSPDs excel in performance in the telecom wavelength range and provide a scalable route towards multi-wavelength and multi-detector architectures. We will implement a two-color quantum lidar system where time-of-flight (TOF) detection with ultralow timing jitter below 10 ps on one wavelength will give information about target distance with 2 mm accuracy, while QHD combined with ECS illumination on a second wavelength will provide quantum-enhanced local spatial resolution. Through beam scanning and synchronized QHD we will realize super-resolved surface profiling. Our consortium is uniquely placed to tackle these challenges by joining leading experts in ultrafast single photon detection, nanophotonic circuit design and quantum light genera
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'MOde-localized mass Sensors with Thermal Actuation and Piezoresistive DEtection'.

assistant: **Objectives**

Micro/nano-electromechanical system (M/NEMS) resonant mass sensors have attracted utmost interest over the past two decades. This is due to their wide range of applications, especially in biochemistry, for instance weighing single molecules, nanoparticles, and even monitoring the growth of living cells. However, their performance is significantly decreased when operated at ambient air and measurements take a considerable time. Therefore, there are two main challenges for MEMS resonant mass sensors: (i) the improvement of the quality factor at ambient atmospheric pressure; (ii) the realization of real-time monitoring with a closed-loop control and interface circuit system. Additionally, higher sensitivity is always a desirable property to further increase the performance of mass sensors.    In this project, entitled “MOde-localized mass Sensors with Thermal Actuation and Piezoresistive DEtection (MOSTAPDE)”, I aim addressing aforementioned challenges by combing thermal actuation and piezoresistive detection for MEMS resonators. With this approach a quality factor of several thousand at ambient pressure can be achieved. As a further novel approach, it is proposed to weakly couple two resonators and exploit the phenomenon of mode localization; by using the amplitude ratio as readout metric compared to the commonly used frequency modulation method; in this way the sensitivity can be enhanced by 2-3 orders of magnitude. Furthermore, the inherent common mode rejection property of mode-localized sensors can be exploited for higher robustness. Finally, particle contamination and blockage are avoided as the proposed sensors do not require small electrode-gaps as conventional capacitive sensors. For the microfabricated sensors, a closed-loop control circuit will be constructed to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Rewriting Rights: Feminist Legal Narra(c)tors, from Arendt to Women’s Courts', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The scene of the trial has always been at the core of feminist theories and practices of law, since it has often been identified as the space in which womens voices and bodies could break into the legal scene in order to claim for justice. The project aims to broaden our gaze of the legal scene adopting a new perspective: those of women who, even if they are not the main legal actors (judges, lawyers, plaintiffs), engage with the language of rights in order to re-tell, re-write or re-stage a trial from their situated position. Their voices do not limit to narrate the event of the trial, but actually perform a retrial with the dual aim of highlighting the failure of the legal language in doing justice, and offering alternative possibilities to regenerate and re-signify it. From Arendts pioneering report on the Eichmann trial to the experiences of Womens Courts, these both critical and creative practices are disseminated in the feminist field, but they have never been studied together. Through the newly defined concept of Legal Narra(c)tors, this ambitious and timely project aims to produce the first study of these narrative and performative practices of retrial, which have the merit of promoting a critical but not fatalistic approach to justice using as starting point of the reasoning  in line with the feminist situated knowledge  the story of a case rather than a theoretical abstraction. The main objective of the project is threefold: (1) empirically, to build an archive of feminist narrative and performative practices of retrial; (2) conceptually, to provide a definition and a theoretical framework for the new expression Legal Narra(c)tors; (3) normatively, to explore how main legal categories such as equality, difference, recognition, gender, subject (of rights), vict
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Pttis' under Fifth Framework.

assistant: **Concept**

The PTTIS (Physics Teacher Training in an information Society) Conference has been proposed to contribute to the diffusion of recent scientific achievements in the field of Physics Education, and it is mainly focused in the research on Physics teacher's implementations when dealing with new technologies. A block of the researches presented have the aim to diffuse the results of a project funded by DGXII, STTIS, Science teacher Training in an information Society (contract ERB-SOE2-CT-2020). It is the objective of the coordinator and the partners of the project to establish a forum where the problems of physics Teachers training related to the implementation of innovations that come together with the information society can be discussed.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Delivery of PULmonary Therapeutics through TARgetted Delivery using Phononics' to be submitted under Horizon 2020.

assistant: **Abstract**

According to the WHO 235 million people suffer from asthma and 64M people have chronic obstructive pulmonary disease, leading to 3M deaths per year worldwide. The cost of treating patients with all forms of lung disease is ~ €380B p.a., leading to the loss of >50M DALYS. Generally, patients with such respiratory diseases are treated by inhalation of medicines within aerosols, where the therapy (including medicine or biologics used in gene therapy) can be targeted directly to the lung. The accepted wisdom is that such pulmonary delivery requires aerosol droplet sizes of between 1 and 5 μm.  We have now shown that by using a new ultrasonic technology, we can create monodisperse aerosol droplets, which could be used for therapeutic delivery of medicines, genes and RNA to specific regions in the lungs. In one strand of the work we aim to demonstrate that this precise nebulisation technology improves the efficacy of treatment through enhanced drug uptake. In a second strand, we will demonstrate selective targeting of different tissue types in the lungs. For example, the epithelium in cystic fibrosis patients is currently extremely difficult to access leading to limitations in the amount and quality of data obtained for pre-clinical and clinical gene therapies. Similarly, targeting vascular cells is an appealing treatment for patients with pulmonary arterial hypertension, although, again, effective delivery necessitates that the therapeutic system transits defined and substantial anatomical barriers. The overall aim is to demonstrate that this new technology can define routes to new therapies, improve clinical outcomes and reduce healthcare costs. To achieve this we will develop a prototype nebuliser based upon proprietary technology and show that different medicines and gene
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Factories of the Future Resources, Technology, Infrastructure and Services for Simulation and Modelling 2' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Fortissimo 2 will drive the uptake of advanced modelling, simulation and data analytics by European engineering and manufacturing SMEs and mid-caps. Such an uptake will deliver improved design processes, better products and services, and improved competitiveness. For the European Union as a whole this means improved employment opportunities and economic growth.The importance of advanced ICT to the competitiveness of both large and small companies in the engineering and manufacturing domain is well established. Despite early successes in this area, there are still many barriers to the uptake of such solutions, not least of which are the initial cost and complexity of adoption, particularly in the context of challenging trading conditions. This proposal targets the ICT Innovation for Manufacturing SMEs (I4MS) action line (Phase 2) and builds on Phase 1 of that initiative.Phase 2 addresses the adoption of next generation ICT advances in the manufacturing domain. At the core of Fortissimo 2 are three tranches of Application Experiments (~35 in total). An initial set is included in this proposal and two further sets will be obtained through Open Calls for proposals. These experiments will be driven by the requirements of first-time users (predominately SMEs) and will bring together actors from across the value chain, from cycle providers to domain experts via the Fortissimo Marketplace. This will enable innovative solutions to manufacturing challenges, leading to new and improved design processes, products and services. A key feature of Fortissimo 2 will be the adaption of the Marketplace to meet the needs of end-users. It will offer a responsive and reliable service to companies which want to access HPC and Big resources and expertise.Fortissimo 2 initially involves 732 mon
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Boosting the Exploitation of Standardisation Inputs from European Projects' to be submitted under Horizon Europe.

assistant: **Abstract**

Contributions from industry, research and end-users, involving experts that represent diverse stakeholders are crucial for the standardisation development. However, the standards-making process and rules are sometimes at odds with the culture and practice of research. STAND4EU aims to strengthen the links between research, innovation and standardisation ensuring that standardisation is an integral part of the European research and innovation landscape. STAND4EU will map and identify key stakeholders and actors involved in standardisation activities at national, regional (EU) and international level to allow a proper identification of the obstacles hampering the standardisation efforts within the scope of 4 main technological domains: Additive Manufacturing, Welding, Smart manufacturing/Industry 4.0/Digitalization/ Artificial Intelligence & Circular Economy.The key bottlenecks in the standards development lifecycle will be identified and to overcome the obstacles on the standards setting process a plan will be develop with recommendations and solutions to make the standards development process more efficient between the stakeholders from research, innovation and standardisation. A STAND4EU interface will be created to facilitate the collection and the sharing of information about the obstacles and associated remedies and best practices towards the industrial and research & innovation community, the standards developing organisations, the public authorities and other relevant stakeholders.  This will include pointers to available supporting services, networking services, herewith acting as a one-stop-shop for all related standardisation research and innovation mattersAll the proposed solutions will be validated with the relevant actors and stakeholders to transfer the met
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Analysis, Verification, and Synthesis for Infinite-State Systems', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The central objective of this project is to investigate key algorithmic verification questions concerning two fundamental mathematical structures used to model and analyse infinite-state systems, namely discrete linear dynamical systems and counter automata, in both ordinary and parametric form. Motivated especially by applications to software model checking (more specifically the termination of linear loops and predicate abstraction computations), as well as parametric real-time reasoning and the verification of Markov chains, we will focus on model-checking, module-checking, and synthesis problems for linear dynamical systems and one-counter automata against various fragments and extensions of Linear Temporal Logic (LTL) specifications. The key deliverables will be novel verification algorithms along with a map of the complexity landscape. A second objective is then to transfer algorithmic insights into practical verification methodologies and tools, in collaboration with colleagues in academia and industrial research laboratories.We will build on a series of recent advances and breakthroughs in these areas (some of which from the PI’s team) to attack a range of specific algorithmic problems. We believe that this line of research will not only result in fundamental theoretical contributions and insights in their own right—potentially answering mathematical questions that have been open for years or even decades—but will also impact the practice of formal verification and lead to new and more powerful methods and tools for the use of engineers and programmers.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Modified Gravity on Trial' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The main goal of this project is to study the fundamental properties of field theories of space-time, their cosmological consequences and observational signatures. My approach aims to use the next generation of cosmological and astrophysical observations to test the validity of General Relativity on scales where it has not been fully tested yet and its resilience against alternative theories with modifications on cosmological scales. I will first study the implications of the quantum aspects of modified gravity theories beyond the tree level analyses for their viability, consistency and predictability. This will reduce the allowed alternative theories significantly. I will then investigate the physical consequences of these theoretically promising theories for cosmological and astrophysical scenarios. As part of my approach, I will use large galaxy surveys to constrain effects on the dynamics of cosmic structure formation from these modifications of gravity. In addition, I will confront modified theoretical predictions with Planck measurements of the Cosmic Microwave Background, type-Ia supernova data, measurements of the Baryon Acoustic Oscillations and gravitational lensing. Along the way, my group and I will crucially contribute to the development of the necessary analytical and numerical tools to exhaustively analyse such data in the search for modifications of gravity. In addition, the recent detection of gravitational waves by the LIGO team has paved an exciting new avenue for testing gravitational theories. These new observations will put even more stringent constraints on alternative theories. As part of the proposed research, I will also extensively exploit this new observational channel to test the validity of General Relativity and put new effects of modified
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Understanding of ORMDL3 biology will provide novel insight into the pathogenesis of asthma' in the context of a Seventh Framework call.

assistant: **Objectives**

Asthma affects up to 30 million children and adults in Europe and many more around the world. Today, asthma can be treated but not cured. Major efforts to understand the mechanisms leading to the disease are needed to better intervene and potentially prevent asthma.Genetic susceptibility and environmental factors are thought to cause the disease. However, until recently systematic approaches to identify major genetic susceptibility factors were not feasible. Within the GABRIEL Consortium we lately identified a novel and major susceptibility locus specifically for childhood asthma on chromosome 17q21 by genome wide association studies. ORDML3, a gene in that locus seems to contribute significantly to the association with asthma. ORMDL3 is coding for a protein with so far unknown function located in the endoplasmic reticulum.With this project we aim to increase our understanding of ORMDL3 function and its role in asthma pathogenesis. Collaborating with the National Jewish Hospital in Denver, we will use transgenic mice to determine the biological profile of ORMDL3 in different cells and tissues and to identify interaction partners and pathways that involve ORMDL3. We will study the role of ORMDL3 in asthma genesis using asthma mouse models and explore the potential of ORMDL3 as a therapeutic target.This project will provide the opportunity to increase our knowledge on asthma considerably and at the same time, give the opportunity to acquire new research skills at the post doc level exactly as outlined by the aims of the “Marie Curie Outgoing Fellowship”. It will allow a substantial transfer of knowledge and establish close ties with one of the top 5 immunology centers in the US. Upon return from the US, the applicant will be integrated in a highly active and supportive re
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'MKlp2 - a mitotic kinesin and a prime target for cancer therapy', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Mklp2, a mitotic kinesin and a prime target for cancer therapyMKlp2 belongs to kinesin 6 family and was first identified as an effector protein of small G protein Rab6A, involving in the retrograde transport between Golgi and ER. While its function in Golgi-ER trafficking awaits further study, MKlp2 has been shown to play crucial role in mitosis. It is essential to relocate chromosomal passenger protein Aurora B and the mitotic regulator Plk1 to the central spindle during anaphase. Depletion of MKlp2 results in failure of cytokinesis. In addition, MKlp2 is overexpressed in several human tumor cells and inhibition of MKlp2 reduces the tumor cell growth. Those properties make MKlp2 a prime target for developing anti cancer drugs.MKlp2 has been shown to interact directly to Plk1 and Mad2, the mitotic checkpoint complex protein. However, the mechanism of MKlp2 motor protein and how those interactions may regulate its function is unknown. In addition, MKlp2 possess unique sequences in its motor domain compared to other kinesins which may render its mechanism of nucleotide/microtubule binding. To understand how MKlp2 functions and how it’s regulated during mitosis, we propose a thorough functional and structural characterization of this interesting motor protein.Aim1.Functional and structural characterization of the motor domain of MKlp2, the kinesin involves in cytokinesis and a potential target for anti-cancer drugsAim2.To study in detail the interaction between MKlp2 and Plk1, its regulation of the function of MKlp2, and to determine the structure of the complexAim3.To characterize the interaction between MKlp2 tail domain and Mad2, the structure of the complex, and the role of the interaction in cytokinesisOur results from this multidisciplinary proposal will provide valu