RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Fighting against obesity in Europe”: The role of health related-claim labels in food products' (OBESCLAIM) targeting Seventh Framework.

assistant: **Abstract**

The aim of this project is to investigate whether and how health-related claim labels in food products lead consumers to choose healthier food diet and therefore, nutritional and health labeling could be considered a valid tool to fight against obesity in Europe taken into account also consumers’ personal characteristics (socio-demographic, economic, nutritional and health status etc) and psychological and emotional factors. Therefore, different aspects will be investigated using a multidisciplinary approach: 1) The prevalence of the health-related claims labels in the food market; 2) The consumers’ understanding, use, perception and attitudes towards health-related claim labels; 3) How health-related claim labels in food products lead consumers to choose healthier food diet  and, therefore, these claim labels potentially help to reduce obesity prevalence in Europe; and 4) The consumers’ preferences for health-related claim labels and the role of economics, social, psychological and emotional factors. The current work seeks to contribute to this cross-disciplinary stream by further examining food carrying on health-related claims as symbols perceived by European society, focusing on consumers´ emotions, and psychological and behavioural aspects, by using concepts of economics, behavioural economics and social psychology  and by the implementation of focus groups, interview experts and field experiments
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Novel biocontrol agents for insect pests from neuroendocrinology' to be submitted under Horizon 2020.

assistant: **Abstract**

Insects are the most diverse Class of life on earth, and different insects can be essential for, or highly damaging to, agriculture, horticulture and forestry. There is a pressing need, not just for new insecticides to combat resistance, but more specific, “greener” insecticides that target deleterious insects while sparing beneficial ones. This proposal aims to identify such insecticides by turning the insects’ own hormones against them, both by designing artificial neuropeptide “mimetic” analogs as candidate compounds, and by generating transgenic insects that carry deleterious neuropeptide payloads within them, that can propagate through a population and impact on survival at times of stress.We have assembled an international multi-actor consortium from EU member and associated member states, as well as a third country partner, with unparalleled experience in insect functional genomics, neuropeptide physiology, synthetic chemistry and synthetic biology, and in field-testing of candidates. Established links to agricultural, horticultural and forestry end-users, agencies/advisors and our SME partners ensure relevance to user need; and set out a pathway to exploitation and implementation of our results, for impact across three major economic sectors in the EU and globally.We will deliver novel, ‘green’ neuropeptide-based insect pest biocontrol tools by:• utilising ‘beyond the State-of-the-Art’ technologies based on two approaches: rational design of neuropeptide hormone analogues; and development of genetically-encoded neuropeptides for translational insect synthetic biology in genetic pest management. • bridging outstanding research and technology in neuroendocrinology and genetics to end user need, to ultimately produce neuropeptide hormone analogues and genetic pest
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'NUTRIENT FLUCTUATIONS AND THE INTEGRATIVE STRESS RESPONSE AS METABOLIC CELL FATE DETERMINANTS IN B CELL LYMPHOMA' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Metabolic reprogramming enables cells to adopt different phenotypes, providing flexibility in response to environmental stress, of particular relevance during tumour development. I recently demonstrated that the transcription factor MITF, known regulator of cell transitions in melanoma, controls the expression of the fatty acid (FA) desaturase SCD1. The MITF/SCD1 axis maintains cell differentiation, while its suppression by starvation-induced Integrative Stress Response (ISR) originates dedifferentiation and melanoma progression. Our findings support that metabolic rewiring and phenotype switching are interconnected events that govern tumour progression.As in melanoma, B-cell differentiation depends on MITF activity, FA metabolism and a dynamic modulation of ISR, but weather an interplay among these factors dictates B-cell fate is still unknown. Importantly, MITF is regulated by mTORC1/RagGTPase signalling, pathway frequently mutated in B-cell lymphomas. I hypothesize that the ISR/MITF axis and FA metabolism enable normal and pathological B cells to adapt to stress, and critically licenses switches in phenotypic identity and B-cell behaviour. Thus, I will establish if and how MITF and FA composition control B-cell transitions and impact lymphomagenesis, along with its regulation by the ISR. We propose that abnormal ISR and MITF/SCD1 deregulation corrupts B-cell differentiation process, contributing to lymphomagenesis. This proposal aims at shedding light on the interplay between nutritional signals and stress-related cellular responses that precipitate cancer cell transitions through the regulation of specific transcriptional programs controlling metabolic rewiring.


**Keywords:** MITF, MiT family members, ISR, fatty acids, nutrients, RAGC mutations, B cell, cell fate,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'OPtimisation for low Environmental Noise impact AIRcraft' under Seventh Framework.

assistant: **Concept**

Reducing noise from aircraft operations perceived by airport neighbouring communities is a major challenge facing the aircraft manufacturing industry, social society and the air transport business. By adopting a whole aircraft approach based on the latest developments in active / adaptive technologies, flow control techniques and advances in computational aero-acoustics applied to the major causes of noise at source, OPENAIR aims to deliver a step change in noise reduction, beyond the SILENCE(R) achievements. The workplan clearly supports realistic exploitation of promising design concepts driven by noise reduction and will result in the development and validation up to TRL 5 of “2nd Generation” technology solutions. OPENAIR’s multidisciplinary approach and composition is suited to the projected integrated, lightweight solutions. The process includes a down-selection in mid project. The selected technologies will be subjected to scaled rig tests, and the resulting data will support assessment of the noise reduction solutions on powerplant and airframe configurations across the current and future European range of products. The project exploitation plan will include detailed proposals for further demonstration in the Clean Sky JTI. The verification of the technologies applicability will be assured by addressing identified integration and environmental tradeoffs (performance, weight, emissions). In this way OPENAIR will develop solutions that can play a significant role, in continuity with the previous Generation 1 effort, enabling future products to meet the ACARE noise goals and improving current fleet noise levels through retrofitting. This capability is key to providing the flexibility needed to simultaneously accommodate market requirements in all segments, global tr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Semantic Indexing of French Biomedical Data Resources - mobility' (SIFRm) under Horizon 2020.

assistant: **Objectives**

The Semantic Indexing of French Biomedical Data Resources (SIFR - www.lirmm.fr/sifr) project investigates the scientific and technical challenges in building ontology-based services to leverage biomedical ontologies and terminologies in indexing, mining and retrieval of biomedical data. We will build and improve an ontology-based indexing workflow (Annotator) similar to what exists for English but specialized for other EU languages, starting with French. This will be the first step in offering semantic and multilingual search and mining of biomedical data resources. Our main goal is to enable straightforward use of ontologies freeing health researchers to deal with knowledge engineering or multilingualism issues and to concentrate on biological/medical challenges. SIFR (2013-2017) is a collaborative action between LIRMM & BMIR currently mainly funded by the French National Research Agency (ANR) Young Researcher program. This proposal (SIFRm) aims to fund the mobility of Dr. Clement Jonquet, SIFR’s principal investigator, assistant professor at LIRMM, to Stanford University. Stanford BMIR, head by Pr. Musen, is a worldwide leader providing (English-)ontology-based services to assist health professionals in the design of biomedical knowledge-based systems. BMIR is the birthplace of tools such as Protégé or BioPortal and scientific methodologies such as data driven medicine that Dr. Jonquet will acquire and reuse in a multilingual (e.g., French) and multidisciplinary (e.g., agronomy) context. During the return phase, a secondment is planned within INRIA ZENITH team, head by Dr. Valudriez, renown for distributed big data management. SIFRm will enable development of innovating scientific services to make annotation goes beyond English and reach another level in terms of vari
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Self-assembly of confined colloidal objects for the study of nano-optic phenomena' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

We have demonstrated the presence of attractive interactions arising in low ionic strength solution between charged soft-matter objects and highly curved regions of like-charged confining surfaces. These unexpected interactions result in stretching of DNA and trapping of colloidal particles in solution in a nanofluidic slit. This proposal seeks to further understand the attractive interactions arising between colloidal objects and like-charged confining walls in low-ionic-strength solution, in order to better control the underlying self-assembly process. The controlled self-assembly of arrays or arbitrary arrangements of discrete charged metal or dielectric nano-objects will permit the investigation of plasmonic and photonic phenomena in two dimensions, e.g., plasmonic coupling of resonantly excited metal nanoparticles, modification of fluorescence emission of single emitters diffusing in solution very close to discrete metal nano-objects, realization of novel ordered and disordered arrangements of nano-objects (e.g. dielectric particles like TiO2) for studying light scattering phenomena in two dimensions. One of the chief advantages of the self-assembly technique described here over conventional fabrication techniques is that the substrate surface structure which directs self-assembly of the optically active element acts as a “rewritable surface” enabling the investigation of the plasmonic and photonic properties of ensembles of particles of similar surface charge but variable dielectric properties.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Building Outstanding Opportunities for Science and Talent' (BOOST), addressing dissemination and exploitation.

assistant: **Impact**

The BOOST project addresses the significant disparities in innovation capacity among the EU Widening Countries, primarily in Eastern Europe. Although these nations excel in academic research, they struggle to translate their achievements into commercially viable products and services. This gap negatively affects the social, financial, and environmental sustainability of these regions, limits economic growth, and exacerbates issues like brain drain and low career opportunities for researchers and innovators.BOOST aims to strengthen the R&I capabilities of Widening Countries by fostering collaboration between academic and non-academic sectors. It focuses on enhancing career opportunities and entrepreneurship by providing researchers with the skills needed to succeed in both academic and industrial settings. A key element is the creation of the BOOST Learning Environment, which will facilitate knowledge exchange and collaboration among organizations across Europe, giving access to a rich database of tools, resources, and learning modules.Central to the project is the implementation of the BOOST ERA Talents Scheme, which provides 12-month mobility opportunities for 60 researchers, improving their practical skills through placements in industry settings. The scheme also includes five tailored learning modules, and each participant will receive a Personal Career Development Plan to support long-term career advancement.The project ensures that at least 30% of mobility participants will be women or individuals from underrepresented groups, addressing the imbalance that persists in R&I fields. BOOST provides broad sectoral expertise through its consortium partners. By focusing on skill development, practical training, and cross-sector collaboration, the project will create a sus
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Textile-Based Wearable Soft Robotics with Integrated Sensing, Actuating and Self Powering Properties' to be submitted under Horizon Europe.

assistant: **Abstract**

Wearable soft robotic devices for rehabilitation and motion assistance have emerged in the past decade as promising robotic systems owing to their adaptable morphologies. Soft robotics allow safer human-robot interactions, as opposed to rigid exoskeletons made of metals. Elastomers and textiles have become attractive low-cost and flexible material solutions to build wearable soft robots. Despite their high potential, the demonstrated solutions of previous studies are bulky, unreliable, non-scalable, and have limited portability and mobility. All those drawbacks do not allow practical applications of soft robotic devices for at home assistance and rehabilitation during activities of daily living, where they are intended and most needed. The core objective of TEXWEAROTS is to develop untethered knitted soft robotic assistive devices to overcome current drawbacks related to the wearable soft-robotic system reliability, mobility, sustainability, and integration. TEXWEAROTS focuses on the development of a knitted robotic glove free from bulky components with seamlessly integrated actuation, sensing, and self-powering functionalities. With my solid experience in textile manufacturing, soft sensors, and soft robotics, I will leverage the latest advances in digital machine knitting to manufacture 3D actuator shells with the integrated functionalities in a monolithic manner. This will lead to garment-like customizable textile-based robotic devices which are highly scalable and reliable. Furthermore, I will enable thermally powered fluidic actuation mechanism through integration of soft Peltier cooling functionality which enhances the actuator response time needed for motion assistance applications. TEXWEAROTS combines textile and material science, physiotherapy, robotics, electr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Chromatin re-organization in response to replication stress' under Horizon Europe.

assistant: **Concept**

Background and unmet need: The mammalian genome is a highly organized structure where distinctchromosomal domains occupy discrete territories and position in a non-random fashion. Genomeorganization also determines the proper functioning of various biological processes, including DNAreplication. Genome organization has been widely studied in the context of gene regulation, whilerecently the role of genome organization in mediating DNA damage repair at DSB sites has also cometo light. However, there is scarce information on how newly replicating region is organized in responseto replication stress.Hypothesis to be tested: My hypothesis is that stalled replication forks, especially at the regions proneto acquire breaks, undergo compartmentalization/re-organization within the 3-D nuclear space inresponse to replication stress to allow efficient fork protection and fork restart ability.Objectives: This unique multidisciplinary project will yield critical information to reveal hiddenconnections of chromatin organization, replication fork stability and chemoresistance. With this ERCproject, I will determine for the first time i) the mechanistic insights of chromatin organization changesmediated by chromatin remodeling activity in response to replication stress, ii) identify novel chromatinmobilizers associated with replication forks and iii) determine the significance of chromatin reorganizationto cope with replication stress for establishing resistance towards chemotherapeutic drugsin cancer cells and patient samples.Expected Outcomes: My project will not only advance our fundamental knowledge on spatial &temporal reorganization of chromatin architecture containing stressed replication forks, but it also has ahigh potential to contribute to identifying novel targets aimed at
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'EFFECT-SME  Enhancing and Facilitating Funding Evaluation and data Collection Techniques focused on start-up/SME support programmes'.

assistant: **Objectives**

The EFFECT-SME project’s main objective is to enhance the quality of start-ups’/SMEs’ innovation support programmes through the development of an efficient and effective methodology assessing the impact of the support programmes on start-ups/SMEs.   Assessment of the effectiveness of start-ups’/SMEs’ supporting measures and adaptation of lessons learned into the modification of current start-up/SME support programmes is the key aspect to continuous improvement of support and the policy itself.  The aim of the project is to achieve improved, targeted and more efficient support to start-ups and SMEs. The project partners will share own approaches to complete them with relevant desk research outputs, developing new topics and approaches to more effective monitoring and evaluation and to put the new impact methodology into practice. The project consortium will apply Twinning+ methodology via 3 peer learning interactive workshops focused on impact evaluation of start-up/SME support programmes from different perspectives of 3 partners – combining different levels of experience, methodology approaches and balanced geographic scope: Czechia (MSIC), Germany (S2i) and Spain (Madri+d). The desk research on available methodologies will complete the peer-learning of the partners. The Design Option Paper (DOP) on efficient impact evaluation will stand for the key deliverable of the project. The innovative methodology will be disseminated through numerous business support networks for further exploitation by innovation agencies (IA) in Europe.Project duration: 3/2021 – 2/2022 Budget: 50 000 Euro


**Keywords:** peer learning, support programmes, evaluation, SME, start-ups, assesment, twinning +