RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Transport System with Artificial Intelligence for Safety and Fare Evasion' (TRAINSFARE) targeting Horizon 2020.

assistant: **Abstract**

Our project’s main objective is to develop a decentralized, interoperable and flexible system to reduce some operational problems at mass transport systems and to increase their safety. One of the concerns of Mass Transportation Operators (MTO) worldwide is the significant amount of users that avoid paying (fare dodging), amount that is increasing nowadays (estimated value of €600 million/year).In the case of rail and metro, the installation of mechanical fare gates activated with magnetic cards helps reducing fare dodging but some users take advantage of the gate closing delay (necessary for safety reasons) and pass right behind the previous user, without validating any ticket whatsoever (tailgating). There is currently no effective solution for this problem except permanent human surveillance at the gates or the frequent deployment of mass controls: a group of inspectors checks every passing user. These mass controls are cumbersome, inconvenient for the paying user and easily avoidable by the fare dodger.HAL has developed an artificial vision system that automatically detects tailgating and allows the selective interception of the suspected wrong-doer even before they reach the platform.The system is being developed in collaboration with a globally respected MTO active in Barcelona, FGC (Ferrocarrils de la Generalitat de Catalunya), within their Smart Train program. A pilot under regular operating environment has proven the effectiveness of the system.With this proposal, we plan to elaborate a detailed feasibility study (Phase 1) that will possibly recommend to opt for Phase 2 funding later on, necessary for extended R&D and for a rapid worldwide dissemination of our solution.  We expect to further expand our artificial vision technology (combined with mobile technolo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Max-born-institute for nonlinear optics and short pulse spectroscopy (MBI)' (MBI).

assistant: **Concept**

Description:The Max Born Institute for Nonlinear Optics and Short Pulse Spectroscopy (MBI) in Berlin, Germany, is a state- and nationally funded large-scale research facility, maintaining a scientific profile with three principal topics:1) Research to advance the state of the art in short-pulse and high-intensity lasers;2) Interdisciplinary applications in basic research and in emerging key technologies;3) Active encouragement of collaborations by offering access to the research facilities ( MBI Application Laboratories).Besides topic (1). occupying about one third of the institute's projects, research concentrates on short-pulse light-matter-interaction at the atomic and molecular level (2). MBI maintains a competitive status with unique research possibilities and instrumentation in each of these topics, but derives its particular strength from their synergetic combination. This speciality is offered to European visitors through active encouragement of collaborative research, and access to specialized instrumentation (3). In particular, MBI operates two dedicated Application Laboratories", containing advanced femtosecond and high-intensity lasers, and the joint MBI-BESSY II Beam-line, combining advanced short-pulse laser systems with 3rd generation synchrotron radiation in the neighbouring BESSY II facility.Application:Interested researchers are recommended to consult the www-server http://limans3.mbi-berlin.de for complete guidance through the application procedure, or to contact the facility directly under mbi-berlin.de. Applications will be reviewed and selected by an external panel of referees.Project Manager:Joern Kaendler, Max-Born-Institute for Nonlinear Optics and Short-Pulse Spectroscopy(MBI), Max-Born-Strasse 2A, Berlin 12489, GermanyTel: +49-30-63921500Fax:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Innovating dialogue and problems appraisal for a safer Africa' (SaferAfrica) targeting Horizon 2020.

assistant: **Abstract**

SaferAfrica project aims at establishing a Dialogue Platform between Africa and Europe focused on road safety and traffic management issues. It will represent a high-level body with the main objective of providing recommendations to update the African Road Safety Action Plan and the African Road Safety Charter, as well as fostering the adoption of specific initiatives, properly funded. The involvement of Development Banks will ensure the identification of available resources and the definition of suitable schemes of funding. The activity of the Platform will also focus on the reinforcement of the endogenous African capabilities through the dissemination of the EU know-how. Twinning Programs will be set up, besides the conduction of different training activities. Local contexts will be duly taken into account and studies on specific risk factors as well as transferability analysis of measures already tested elsewhere will be conducted. The project activities will be oriented to the “Safe System” approach and grouped in four pillars: Road Safety Knowledge and Data; Road Safety and Traffic management Capacity Review; Capacity Building and Training; Sharing of Good Practices. The platform will work at two levels. A decision making level, run by a Management Board basing its actions on information provided and activities carried out by a technical level, with established Working Groups addressing specific topics. The Management Board will be constituted by prominent institutions like EC, the African Union Commission, Financial Institutions, Regional Economic Communities (UN). The technical level will involve government and research institutions, international and stakeholders organizations (e.g. NGOs), with a fair balance between African and EU partners, even for what concer
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Contextual Radio Cues for Enhancing Decision Making in Networks of Autonomous Agents' (CUE-GO).

assistant: **Concept**

The CUE-GO project aims to conceive a novel methodological framework for enhancing the decision-making capabilities of autonomous agents through the exploitation of contextual radio cues of the environment. Radio cues represent a quantum leap from the traditional concept of features, usually retrieved by vision-based systems, as they contain electromagnetic information with semantic meanings (contextual) enabled by radio-frequency sensors, like those at TeraHertz bands. The elaboration of contextual radio cues allows a far-reaching prediction of the outcomes of agents behaviors and ultimately yields a more efficient navigation in social environments, more accurate localization of people and objects, and enhanced cooperation toward a common mission goal. In interpreting contextual radio cues, agents exchange their sensed information in a way that considers other agents expertise, i.e., their abilities to process environmental stimuli.To achieve this vision, I will: (1) develop a general framework for the decision-making of autonomous agents that emulates the human capability of interpreting cues for anticipating an actions course; (2) conceive and design methods for extrapolating contextual radio cues based on high-resolution semantic mapping of the environment; (3) conceive and design cue-guided localization and navigation algorithms that will boost ambient awareness; (4) conceive new methods and metrics to assess the agents skills in associating contextual radio cues with statistical models that accurately predict future rewards or punishments; (5) develop collaboration schemes accounting for the assessment of agents expertise.Thanks to a multidisciplinary approach, combining diverse knowledge from behavioral neuroscience to engineering, this project will lead to a sig
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Training in Modern Quantitative Methods and High-Performance Computing for Finance' (HPCFINANCE) targeting Seventh Framework.

assistant: **Abstract**

HPCFinance, a 4-year multi-site Marie Curie Initial Training Network in modern quantitative methods and High-Performance Computing for Finance, provides solutions to managing financial risks by high-performance computing. HPCFinance will help improve the financial strength of banks, pension funds, insurance companies, other financial institutions and households in Europe. The main goal of the network is to enhance the career development of 12 early-stage researchers and 2 experienced ones in finance-related sectors.Currently, while recovering from the financial crisis, the European financial world and academic researchers are facing major challenges to create and apply more reliable quantitative models and methods to manage risks. Simultaneously, computationally challenging new hybrid products combining traditional financial investments with insurance policies are gaining popularity. Consequently, demand for experts in finance with superior computing skills is growing rapidly.HPCFinance consists of 7 universities and 8 companies, representing investment and insurance companies, banks, consultants, and high-performance computing solution providers. The network’s US partners provide invaluable experience for benchmarking and knowledge transfer into Europe. This world-class network provides training in robust financial models and numerical methods on high-performance computing platforms with emphasis on variable annuities and asset and liability management. The intended research is not only academically but also practically relevant as the program is built around real life challenges identified together by the academic and private sector partners. To bridge research and practice, all researchers contribute to the private sector via secondments. The major societal impacts o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Reconstitution of Chromosome Replication and Epigenetic Inheritance' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

A PubMed search for ‘epigenetic’ identifies nearly 35,000 entries, yet the molecular mechanisms by which chromatin modification and gene expression patterns are actually inherited during chromosome replication — mechanisms which lie at the heart of epigenetic inheritance of gene expression — are still largely uncharacterised.   Understanding these mechanisms would be greatly aided if we could reconstitute the replication of chromosomes with purified proteins.  The past few years have seen great progress in understanding eukaryotic DNA replication through the use of cell-free replication systems and reconstitution of individual steps in replication with purified proteins and naked DNA. We will use these in vitro replication systems together with both established and novel chromatin assembly systems to understand: a) how chromatin influences replication origin choice and timing, b) how nucleosomes on parental chromosomes are disrupted during replication and are distributed to daughter chromatids, and c) how chromatin states and gene expression patterns are re-established after passage of the replication fork.  We will begin with simple, defined templates to learn basic principles, and we will use this knowledge to reconstitute genome-wide replication patterns.  The experimental plan will exploit our well-characterised yeast systems, and where feasible explore these questions with human proteins.  Our work will help explain how epigenetic inheritance works at a molecular level, and will complement work in vivo by many others.  It will also underpin our long-term research goals aimed at making functional chromosomes from purified, defined components to understand how DNA replication interacts with gene expression, DNA repair and chromosome segregation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Molecular mechanisms of persistent antigenic stimulation in cytomegalovirus infection' (CMVAGSTIMULUS), addressing dissemination and exploitation.

assistant: **Impact**

Cytomegalovirus (CMV) is a ubiquitous herpesvirus, latently persisting in the majority of the adult population worldwide. In these hosts, CMV-specific memory cells dominate the immune memory compartment. It follows that CMV-specific T-cells dominate the memory compartment of the majority of the human population worldwide.I propose to define within this project the molecular mechanisms driving the inflation of CMV-specific T-cells. My central hypothesis is that expression levels of CMV peptides during latency, along with the avidity of T-cell receptors for peptide MHC complexes, define the amplitude of T-cell responses. A corollary hypothesis is that vigorous T-cell responses in CMV infection are defined by factors that drive CMV gene expression during latency, such as inflammatory stimuli.This hypothesis will be verified in a model of in vivo CMV latency and immune monitoring. We will benefit from state-of-the-art inducible genetic systems, where recombinant mouse CMV will be deployed in transgenic mice. In latently infected mice, we will induce or suppress the expression of immunodominant CMV genes, and define downstream effects on T-cell response kinetics. In parallel, we will define the T-cell responses to high and low avidity peptides.Understanding the mechanisms driving the strong T-cell response to CMV is of outstanding biological and clinical relevance. If strong T-cell responses may be redirected to target heterologous antigens of interest, CMV-based vaccine vectors might potentially allow the development of HIV or tumor vaccines. On the other hand, it is speculated that the control of latent CMV may overcommit the aging immune system and exhaust the T-cell repertoire. Given the CMV pervasiveness, discerning the mechanisms of its T-cell induction may define nove
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The structural biology of TrkB-BDNF signalling' to be submitted under Horizon 2020.

assistant: **Abstract**

Neuronal circuit development involves multiple stages that are regulated by neurotrophic factors. One of the key players, the brain-derived neurotrophic factor (BDNF), is involved in the development and functional modulation of circuits by promoting neuronal survival, synaptogenesis, synaptic transmission and synaptic plasticity. BDNF acts by binding to the tropomyosin-related kinase receptor B (TrkB), a type-I membrane protein, to trigger downstream signaling. However, the molecular architecture of this complex and the mechanism of signal propagation across the membrane remain unknownThe key aim of this project is to define in structural and mechanistic terms the steps leading to TrkB activation upon BDNF binding. I will use X-ray crystallography to determine the structure of the extracellular TrkB-BDNF complex, and validate this model by mutagenesis and biophysical techniques. Single particle cryo-electron microscopy will be used to solve the full-length TrkB-BDNF complex structure. To validate and relate these structures to signaling, structure-based hypotheses will be tested in live cells by fluorescence imaging.Furthermore, to exploit the structural information gained above, I will engineer BDNF molecules with improved physico-chemical properties as well as generate nanobodies against the TrkB extracellular region. These will be  screened by biophysical, structural and cellular approaches to evaluate their (i) binding mode and affinity and (ii) ability of promote TrkB activation. Subsequently, collaborative studies in mouse models will test whether these molecules behave as efficient BDNF mimetics in vivo.This multidisciplinary approach will enable me to define determinants of the TrkB-BDNF complex formation, its activation mechanism, and to use this information to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The return of the heirs' under Horizon 2020.

assistant: **Concept**

This project aims at carrying out a comparative, multi-generational and interdisciplinary analysis of European emigrants’ descendants’ “return” from Chile to Spain and Italy. Italian and Spanish legislation and return programmes give a preferential right to entry and to nationality acquisition to foreign citizens of emigrant descent. These legal frameworks generate massive migrations that can be called the “return of the heirs” - as those who “come back” have inherited a privileged legal status, based on the “legal myth” of ethnically motivated return migration. Almost invisible in research and in the public sphere, these migrations raise urgent issues regarding European identity, citizenship, belonging and family heritage. Indeed, an unquestioned gap between the right to enter and the right to return to European countries informs present-day policies, as more and more countries base their nationality laws on jus sanguinis, giving family inheritance a central role in access to citizenship rights.This programme aims to answer this research question: how is belonging transmitted and re-created in families of emigrant descent and how is it linked to the changing nationality and return laws of the countries their ancestors came from? Its objective is to identify and compare different patterns of belonging production and transmission in families of emigrant descent, with regard to gender, nationhood, ethnicity, regional identity and law. To pursue this goal, the research will be based on a six months ethnographic regional fieldwork in Chile, Italy and Spain and on a qualitative analysis of data conducted with an interdisciplinary approach.The research project will be carried out at the Dipartimento Culture, Politica e Società of UniTo, an interdisciplinary department which w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Political Teratology. The Monster as political concept in the Early Modern Age' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

In this research I intend to focus on the phenomenon of the monster within European political philosophy between the half of 16th century up to the end of 17th century. The primary objective of the research is the construction of the concept of political teratology.My purpose is to reconstruct the debate on monsters on the specific field of political philosophy. On one hand, 'conservative' authors, who employ the metaphor of monster to blame the 'others'. On the other hand the authors who raise the question of a positive concept of 'free monstruosity' which depart from the norm of representation and its judgment.We move in this way from the study of the game of metaphors towards the construction of a theoretical concept from which it will be probably possible to think about history of political modernity and its foundations.The first stage of the research is a theoretical construction of a model to be used to interpret the different functions of the metaphor of the monster through:- The analytical construction of a set of concrete political metaphores as well as the critical study of the concept of metaphor in political philosophy;- A reading of the literature in the various philosophical domains dealing with the metaphor and the concept of monsters;- The theoretical definition of the use of metaphors and concept of the monster. The results to be obtained with this research could be used as useful theoretical instruments for a new problematics concerning the relationship between social institution s and political logic of affects.The expected outcomes could lead to a revival of the classic problem of the relationship between individual and community, towards a new conception of singularity.This project is a research in history of philosophy as much as a conceptual melti