RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'ß-cell Dysfunction in Diabetes: Elucidating the Role of Islet-Associated Mesenchymal Cells' in the context of a Seventh Framework call.

assistant: **Objectives**

Glucose homeostasis relies on tightly controlled release of insulin by pancreatic beta-cells. Diabetes, characterized by increased blood glucose levels, is a chronic disease now reaching epidemic proportions. The most common form of this disease is Type 2 diabetes (T2D), which was previously regarded as a disease of insulin resistance. However, work over the past decadehad shifted this paradigm by implicating beta-cell failure as a key factor in this disease. Despite major progress, the cellular and molecular basis of this T2D is far from being elucidated. Here, I present a novel pancreatic cell population, islet-associated mesenchymal cells (isMCs), which are with close contact to beta-cells in both human and mouse pancreata. My preliminary findings revealed that isMCs function to maintain beta-cells maturity and functionality. I therefore hypothesize that impaired isMCs function serve as an underlying cause for diabetes. To test this hypothesis, we will characterize the continuous requirement of isMCs for glucose homeostasis by their specific depletion in vivo. Next, we will link genes associated with T2D to isMCs function, by manipulating their expression and elucidating the effect on beta-cell function. Finally, we will investigate the source of diabetes prevalence found in pancreatic cancer and pancreatitis patients, by identifying how isMCs ability to maintain beta-cell function is affected in these diseases. To this end, we will use transgenic mouse models and culture systems to specifically manipulate cells and genes, and to study the resultant effect on beta-cell phenotype and glucose homeostasis. The implications of this work are far reaching as they will point to isMCs as a new player in glucose regulation, and as a contributor to beta-cell dysfunction in dia
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The Rediscovery of Catacombs between the 16th and 20th Century in the Mediterranean Basin' (UndergroundMed).

assistant: **Concept**

This project will trace the history of the rediscovery of ancient catacombs between the 16th and 20th centuries across the Mediterranean from a broad European perspective, through studies conducted on travel influx, exploration, archive and museum collections. Catacombs are a valuable and cultural evidence of the transition from Antiquity to the Middle Ages in the Mediterranean basin. However, there are currently no systematic analyses on their rediscovery, since in-depth investigations have only been carried out on a local scale. The study will fill this gap and maintain a strong interest in museum and collection history, which so far has been greatly underrepresented in research. No studies have focused on the role played by catacomb archaeology from a perspective that will assist in building a European common culture. UndergroundMed will trace the history of the rediscovery of catacombs by a vast number of scholars, explorers and others during the aforementioned periods. The research will focus on various countries, using a multi-disciplinary approach combining archaeological surveys, museum studies and archival investigations to highlight the impact of these rediscoveries in European culture and its scientific excellence. The project will open the door to debate in regard to the historical definition of a shared European identity in a borderless Europe. Moreover, it will define the roles that European scholars had on the creation of an international and multicultural research-network while travelling across the shores of the Mediterranean, in search for catacombs. Ultimately, the fellowship will greatly contribute towards the researchers academic career, through networks, research experience and dissemination activities within the host institution together with the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'SECURE AND SUSTAINABLE SUPPLY OF RAW MATERIALS FOR EU INDUSTRY' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

S34I will research and innovate new data-driven methods to analyse Earth Observation (EO) data, supporting systematic mineral exploration and continuous monitoring of extraction, closure and post-closure activities with the aim to increase European knowledge and autonomy on raw materials resources. S34I uses EO not only for the management of technical and environmental issues for a green transition but also to support mining's social acceptance (SLO) and better legislation. Innovative EO-based products/services will provide new or more accurate RM mineral mapping/exploration, environmental and mine monitoring and mine safety, at different phases of the mine life cycle.S34I will exploit Copernicus and other satellite sensors (optical and radar), while other platforms as airborne, low-altitude platforms, ground-based, in-situ techniques/methods, and fieldwork will serve either for calibration, validation or to complement Copernicus data especially at the very high scale spatial or spectral resolution.S34I will provide 6 new open high added value datasets, 14 new methods to analyze EO data using Artificial Intelligence being utilized at different phases of the mining life cycle, 3 new prototyped EO based services for mining stakeholders, 1 research and innovation agenda on EO for mining, a set of recommendations for better policy, and guidelines for EO uptake by the mining industry. S34I results will be validated at six different locations in different phases of the mining life-cycle: (i) land exploration in Spain; (ii) coastal exploration at the Iberian Peninsula Atlantic coast; iii) extraction phase in Austria and; iv) closure/post-closure phase in Finland and Germany.S34I is an EU wide interdisciplinary and complementary team embracing partners from 11 countries and wit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Linknovate – Connect with Emerging Technologies and the Key-Players Behind Them' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The main publishing groups (e.g. Elsevier) perform business intelligence over scientific and technology-based content for which corporations globally pay top dollar (>50k€/license year), leaving SMEs and independent professionals ‘in the dark’. They have to rely on complex patent analysis tools and scientific search engines to make sense of data, and to detect trends and emerging technologies.LINKNOVATE (LKN) brings a disruptive solution, harvesting metadata from multiple sources, not just publications and patents but also more up-to-date sources (e.g. conferences, grants, news), and addressing the opportunity to attract user generated content. These are the foundations of our ‘Discovery engine’.LKN provides business intelligence software tools for our clients to identify emerging technologies and markets, and the key-players behind them.Our mission is to build a tool able:1) equip with a basic understanding of emerging technologies in one-click2) help them understand the emerging verticals inside their topic of interest and keep track of them3) identify forces disrupting that topic, key-players in it and the relationships between themRegarding our value for Europe, we are an SME friendly tool (Freemium model) and aligned with the ‘quadruple helix model’ and the industry 4.0 principles to have a less linear and more open innovation process. Our aim is to become the go-to tool for business intelligence, for technologists and strategists.LKN will be commercialized under a freemium subscription model. With LKN as our growth axis, we expect to reach 9,5M€ in revenue and 55 employees by 2020. Instrument for SMEs is a unique opportunity for us to gain momentum, and reinforce our competitive advantage. During Phase 2 we will focus on the scale-up and the high growth of the com
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Virtual Innovative Learning Laboratories for Global Engineering Education (VILLAGE)' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The aim of VILLAGE is to re-examine the post-pandemic teaching processes and needs of engineering instructors and students for laboratory practice in a multidimensional, multicultural and multidisciplinary context, and to determine roadmaps for new instructional design models in line with the opinions of the stakeholders, to create effective and sustainable instructional models, while developing a pilot virtual lab and its learning materials to test the proposed model.VILLAGE is a joint research and innovation (R&I) project in the context of generating a sustainable learning model for laboratory engineering education considering the new normal and the needs of the instructors with the exchange of staff within partnerships of universities, research infrastructures and SMEs in Europe and beyond, which aims to strengthen inter-sectoral and international collaboration. In general, the existence of some virtual laboratories for engineering education is known, and some variables are effectively used. Beyond the state of the art, this project aims not only to design another virtual lab, but to design a sustainable model for engineering laboratories education based on a multidimensional, multicultural and multidisciplinary analysis.


**Keywords:** engineering education, instructional design, virtual laboratories
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on ''If immortality unveil…'– development of the novel types of energy storage systems with excellent long-term performance'.

assistant: **Innovation**

The major goal of the project is to develop a novel type of an electrochemical capacitor with high specific power (up to 5 kW/kg) and energy (up to 20 Wh/kg) preserved along at least 50 000 cycles. Thus, completion of the project will result in remarkable enhancement of specific energy, power and life time of modern electrochemical capacitors. Advanced electrochemical testing (galvanostatic cycling with constant power loads, electrochemical impedance spectroscopy, accelerated aging and kinetic tests) will be accompanied by materials design and detailed characterization. Moreover, the project aims at the implementation of novel concepts of the electrolytes and designing of new operando technique for capacitor characterization. All these efforts aim at the development of sustainable and efficient energy conversion and storage system.


**Keywords:** electrochemical capacitors, energy conversion and storage, highly porous carbon materials
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'IRREGULAR MIGRANTS IN TIMES OF HEIGHTENED PRECARITY. COMPARATIVE DYNAMICS OF LIVED EXPERIENCE AND AGENCY AMONG DOMESTIC AND FOOD SERVICE WORKERS IN MILAN AND NEW YORK CITY.', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

UNDERPRECAR analyses how deportability-induced precarity influences the lived experience and agency of irregular migrants under shifting and increasingly contrasting migration regimes. Through a comparative ethnography in Milan (Italy) and New York City (USA), it focuses on domestic work and food service—sectors marked by informality and a high reliance on migrant labour—and adopts a gender-sensitive lens. The objectives are: (1) to trace legislative, administrative, and enforcement trajectories at national and urban levels and assess their consequences for deportability-induced precarity; (2) to document how this condition is experienced in everyday life—namely, how it intersects with other forms of precarity, its implications for vulnerability and well-being, and how it is interpreted and conceptualised by migrants themselves; (3) to map individual and collective repertoires of agency, through which migrants navigate deportability-induced precarity, accounting for variation across migration regimes, economic sectors, and gender. The methodology combines document analysis; 30 interviews with civil-society actors, officials and experts; 80 in-depth interviews with migrants (40 per city, split across sectors); participatory diaries and photo-voice with 20 co-researchers; and sustained participant observation. Triangulated analysis will generate open-access datasets and publications, policy briefs and co-produced public outputs. Aligned with the priorities of the MSCA Work Programme, the project will deliver socially engaged research, while equipping the fellow with advanced methodological, open-science and ethics training through international mobility across the City University of New York, Toronto Metropolitan University and the University of Milan.


**Keywords:** reg
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Zeolite modification and application study for nuclear waste water treatment' to be submitted under Fifth Framework.

assistant: **Abstract**

The aim of the present Project is to study the main properties of zeolites: physical, chemical and liquid absorption in order to elucidate the microstructure and ion exchange mechanisms of natural zeolites. Electron irradiation will be carried out to enhance the mentioned properties for a more effective elution of radioisotopes from industrial wastes of atomic stations, which are blown to have a great impact on the environmental conditions of metropolitan areas. The main goals of the Project can be defined as follows: Identification and modification of natural zeolites for their use in Science and Economy; application of zeolites with enhanced absorption properties to elaborate a model cleaning system with high technological efficiency for nuclear waste water treatment.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Ionospheric Climate: development of the Global Reference Ionosphere' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The ionosphere, a layer of plasma in the Earth’s upper atmosphere, has traditionally been modelled by the International Standards Organization (ISO)-recognized International Reference Ionosphere (IRI); however, this model is made up of several sub-models, many of which have not been updated since the 50s and 70s. Since the creation of those models, our understanding of the ionosphere has evolved considerably, more diverse observations have become available, and many of the drivers, upon which these models rely, are no longer available, forcing the use of stopgap drivers whose temporary application has become more than just temporary. Here we propose to redevelop the IRI using novel empirical methods that can make use of nonlinear and indirect measurements that could not be incorporated in the IRI’s present form. We will, furthermore, include a parameterization of the climate change impacts on the ionosphere, which are now expected to have considerable impacts on the future structure of the ionosphere, and will avoid the explicit dependence of the model on driving indices that are no longer being updated. Using this model, we will here also assess the impacts of lower atmospheric forcing and climate change on the ionosphere on a global scale and characterize the implications of these results for radio and navigation systems that propagate signals through the ionospheric medium.As a member of the IRI Working Group, the PI is well positioned to ensure that the model developed here will have a clear pathway to impact. To further ensure take-up of the model, an advisory committee, made up of leading members of the IRI Working Group, ionospheric lower atmospheric coupling, and ionospheric instrument experts, has been assembled and has agreed to support the project. Furthermor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Labour market behaviour and migration: a cross-national comparison of the relationship between occupational and geographical mobility in late-modern societies' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The proposed project will address the link between geographical and social mobility by examining the relationship of individuals’ occupational mobility and their geographical mobility behaviour in the life course. The investigation of the patterns of occupational mobility in connection with geographical mobility will provide insights into career pathways in late-modern societies and so will add to the understanding of the labour market behaviour of people and households. In a broader sense the research seeks to give answer to the question whether there is a rationale for geographical mobility (in order to experience upward occupational mobility) in late-modern societies. Research on the dynamics of employment instability, job mobility and geographical mobility also add to our understanding of social inequality structures. To accomplish this aim, firstly, longitudinal information will be obtained as traditional cross-sectional approaches to longitudinal research cannot capture trajectories of individual life histories and dynamic processes that underlie social change. Secondly, nation-specific structural and institutional contexts with regard to labour markets and related markets such as the housing market and the educational system need to be considered as they shape opportunities and constraints, and in this way influence the choices people make. For that purpose, Germany and Great Britain are chosen for comparison as both countries belong to different welfare regimes. Accordingly, the mobility regimes also differ in both countries. Given the longitudinal requirements of the research objective panel datasets will be used that cover a broad range of social science including employment, residential mobility and housing conditions. For that reason, the German Socio-Econom
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Role of adam 12 in muscle regeneration' (1998-2002).

assistant: **Innovation**

We have previously found that ADAM 12 (A Disintegrin And Metalloprotease) can provoke myogenesis and is upregulated during muscle regeneration, but the mechanisms involved are unknown. We have generated transgenic mice over expressing ADAM 12 and bred them to mdx mice, which are the animal model for Duchenne muscular dystrophy. Interestingly, we found a significantly decreased degree of muscle cell necrosis and a decreased level of serum creatine kinase in these ADAM 12/mdx mice compared to mdx mice. Based on these striking results / we are interested in identifying molecular pathways by which ADAM 12 is implicated in myogenesis and muscle regeneration. For this purpose we will use the microarray technology to study the expression profile of 12000 genes in normal, ADAM 12 transgeneic, mdx, and mdx/ADAM 12 transgenic mice. Genes which expression is significantly modulated will be classified in functional clusters, which should give rise to different hypotheses concerning the molecular pathways of ADAM 12 action in muscle regeneration. We will then use different functional assays to test these hypotheses. Based on our preliminary results, we hypothesize that ADAM12 might contribute to muscle cell survival by playing an anti-apoptotic role. To test this hypothesis we will first focus on the analysis of calcium signaling which is known to be implicated in anti-apoptotic signals. As the analysis of the modulated genes goes on, other hypotheses might rise and will be tested.