RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'BIOphotonic SPECialists for Novel Raman Spectrometer Development'.

assistant: **Concept**

Almost from its discovery there have been grand hopes for Raman spectroscopy to be an ubiquitous tool for chemical analysis. It has the potential to identify substances easily and distinctly from fingerprint-like spectra. This can be done with simple photonic architecture, allowing for potential portable and miniaturised form factors. Unfortunately the overwhelming fluorescence background common to all analytes obscures the weak Raman signal and thus makes this dream unrealised. Finally wavelength modulated Raman spectroscopy (WMRS) represents an innovative solution that delivers fast, fluorescence-free Raman spectra. WMRS has a wide range of potential applications in the healthcare industry from discriminating between cancerous and healthy tissue, to determining drug concentrations in biological liquids and identifying the presence of inflammation and infection. To realise this innovative development MSL require a ‘biophotonics engineer’ that has the correct specialised skills to carry out this development which are not currently available at MSL.MSL is looking to develop WMRS into a novel biophotonics tool capable of revolutionising Raman spectroscopic analysis. The aim of this project is to develop an innovation programme centred on WMRS for biological analysis. However, to realise this innovative development MSL require a ‘biophotonics engineer’ that has the correct specialised skills to carry out this development which are not currently available at MSL. This includes experience and knowledge across photonics development, biological analysis, Raman spectroscopy and programming. To meet this innovation opportunity MSL needs to overcome barriers to recruitment by widening its recruitment pool from UK to EU and increasing visibility. This project provides the framewor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Energy Systems in Transition' (ENSYSTRA).

assistant: **Concept**

To facilitate the necessary energy transition, there is an urgent need for highly trained professionals with the scientific knowledge and professional skills to analyse, understand and design relevant (new) energy systems and governance in different sectors and administration. The proposed project Energy Systems in Transition (ENSYSTRA) aims to train 15 ESRs in this field. The objectives of ENSYSTRA are 1) to develop state-of-the-art science of energy systems transition, scenario analysis and energy modelling tools with emphasis on interdisciplinary model collaboration, 2) to provide ESRs with interdisciplinary, inter-sectoral and applied perspectives on the energy transition, 3) to provide new skills and competences for interdisciplinary analysis, 3) to establish collaboration between key universities and their networks, 4) to create and increase linkages between different academic disciplines, applied research, industry and the public sector, 5) develop links and synergies between relevant scientific arenas, and 6) to contribute to accessible energy science based on open source work environments. By focussing on a prominent ‘’living lab’’ of the energy transition, the North Sea region, the project will bring together a strong network and analytical capacity to understand energy system & scenario modeling; new energy technologies & infrastructures; actor behavior & interactions; and policy & market design, linking the regional to the international scale. Through a carefully designed training programme, ESRs are trained in both scientific and transferable skills with ample opportunity to collaborate between different projects and partners. The total effort will result in major progress in the field of energy system analysis and transition modelling. By the combined use
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'SUPramolEculaR functional nanoscale archItectures for Organic electronics: a host-driven network' in the context of a Seventh Framework call.

assistant: **Objectives**

SUPERIOR aims at providing top-quality cross-disciplinary and supra-sectoral training to a pool of promising young researchers, in an area at the interface between Supramolecular Chemistry, Materials- and Nano-Science, Physics and Electrical Engineering. SUPERIOR appointees will be formally trained in lecture courses, dedicated schools and workshops, and through an ambitious and carefully planned research activity that benefits both from the expertise of world-leading senior investigators and of younger and energetic PIs with remarkable track records in both training and research. SUPERIOR is designed to generate new scientific and technological knowledge by combining supramolecularly-engineered nanostructured materials (SENMs), mostly based on organic semiconductors, with tailor-made interfaces to solid substrates and electrodes, for fabricating prototypes of optoelectronic devices. We are particularly interested in developing multiscale SENMs for transistors (FETs), in-plane diodes single-photon emitters, and especially solar cells (PVDs) and organic light-emitting diodes, OLEDs. The specific training and research objectives are: 1. Supramolecular synthetic chemistry of electrically/optically 1D and 2D (macro)molecules 2. Hierarchical self-organisation of multifunctional SENMs at surfaces. Multiscale SPMs studies of physico-chemical properties 3. Time-resolved photophysical studies of single-molecules and SENMs 4. Time-resolved spectroscopy of materials and devices 5. Modelling the geometric and electronic structures and the optical properties of SENMs 6. Advanced devices processing/(nano)fabrication 7. Formation of controlled interfaces of SENMs with substrate and electrodes 8. Devices I: FETs: Measurement of charge mobility in stacks, also upon photodoping. 9. Devic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Beyond Colours and Flavours on Supercomputers' (BCFS) under Horizon 2020.

assistant: **Objectives**

We propose precision lattice QCD computations aiding the search for new physics beyond the Standard Model. In particular, we will address currently observed anomalies such as those displayed in the anomalous magnetic moment of the muon and lepton flavour universality tests in semi-leptonic B meson decays. We will further supplement searches for new physics through the computation of hadronic inputs, which combined with experimental results allow the determination of elements of the Cabibbo-Kobayashi-Maskawa matrix, thereby providing precision tests of the standard model.We will compute a large set of hadronic form factors of semi-leptonic B(s) and D(s) meson decays including pseudo-scalar and vector finalstates. State-of-the-art computations of these have two major shortcomings: the use of effective theories for the b-quark, and the treatment of vector final states as QCD-stable particles. We will eliminate the former of these by utilising very fine lattices which allow for the direct simulation of the b-quark near its physical mass. The latter will be addressed by merging specialist expertise in the computation of such form factors with that of hadronic scattering processes. This will result in the first calculation that takes the unstable nature of the vector final states in QCD into account. This is of paramount importance in order to address the observed anomalies in the B to D* and B to K* decays. We will compute the full basis of possible currents thereby providing standard model predictions as well as inputs for tests of beyond the standard model theories. Further, we will use the approach of massive QED in lattice QCD computations to provide an independent cross check of the electromagnetic corrections to the hadronic vacuum polarisation.  This work will provide
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Invisible Protein States in Bacterial Chemotaxis: a relaxation dispersion NMR study', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The process by which bacteria bias their motility, enabling them to move towards favourable chemical stimuli and away from unfavourable ones, is called chemotaxis. Motility and chemotaxis are essential for the virulence of many medically important bacteria, including Helicobacter pylori, and also play a role in agriculturally important bacteria, such as the nitrogen-fixing Azospirillum brasilense. The chemotaxis signalling network of E. coli has been extensively studied. The small 14kD protein CheY is an important response regulator in this chemotaxis signalling network, and conserved across all systems. It undergoes a conformational change when activated by phosphorylation which increases its affinity for the FliM component of the flagellar motor switch complex. This results in a change in the direction of the flagellar motor rotation. Most bacteria have much more complex chemosensory systems than those of E. coli. Rhodobacter sphaeroides, the subject of this proposal, has multiple homologues of the E. coli chemosensory proteins. For example, it produces six homologues of the response regulator CheY. These CheY’s, CheY1/2/3/4/5/6, are localized to and are regulated by different clusters of chemosensory proteins in the cell and, while they all bind the motor switch, they have different effects on chemotaxis. The aim of this project is to understand, at the level of individual amino acids, how these six highly homologous CheY proteins are fine-tuned to carry out their specific roles.  State-of-the-art NMR methods will be used to study the structure and dynamics of several CheY’s in their inactive and active states. Low populations of ‘active-like’ conformations that exist in unphosphorylated, inactive CheY’s will be characterized using NMR relaxation dispersion methods.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Spatial spikes: bridging geography and economics to study distance, agglomeration, and policy' to be submitted under Seventh Framework.

assistant: **Abstract**

Economic geographers and geographical economists have been using different methods in order to analyse the location of economic activity. These different approaches to the same topic have, paradoxically, resulted in very similar geographical configurations: a ‘spiky’ world dominated by large metropoli, where intermediate and peripheral locations tend to matter less and less. This apparent similarity in outcomes hides, however, different explanations and policy recommendations. On the explanation side, economists have focused on understanding how the interaction of economic agents in reduced geographical spaces gives rise to large urban agglomerations. Geographers, in contrast, have increasingly concentrated on relative conceptions of space which highlight the importance of the interaction among often far-away places. On the policy side, economists have favoured spatially-blind policies, while geographers are strong advocates of place-based policies.This interdisciplinary proposal will aim at bridging the gap between these two contrasting approaches, by combining concepts and methods developed by economic geographers and geographical economists in order to better understand how economic agglomeration emerges and how the interaction among distant agglomerations contributes to reinforce, rather than weaken, their importance. It will also elaborate on the adequate policy-mix which could be applied in order to optimize policy intervention in diverse geographical context and time settings.In addition to bridging approaches, the proposal will advance knowledge at the frontier of both disciplines with a combination of theoretical and empirical papers revolving around three key sets of questions where new research is particularly needed:1. Origins and microeconomic dynamics of s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'ROLE OF CYCLOPHILIN A IN BONE MARROW VASCULAR PROGENITOR CELL MOBILIZATION AND RECRUITMENT IN THE ANGIOGENIC RESPONSE TO ISCHEMIA'.

assistant: **Concept**

Critical limb ischemia (CLI) is a major health problem; it affects approximately three million people in Western Europe, its prevalence is increasing, adequate medical treatment is not available, and patients with advanced disease are usually unsuitable for revascularization procedures. Since CLI is characterized by inadequate tissue vascularization, much effort has been focused on strategies aimed at promoting neoangiogenesis. Emerging data suggest the clinical potential of vascular progenitor cells (PCs) to restore blood flow to the ischemic limb. Several factors have been shown to influence PC mobilization and homing to ischemic tissue. However, follow-up studies have yet to show long-term benefit. Therefore, the identification of novel molecules represents a major and clinically relevant task. One factor that mediates the cross-talk between PCs and a variety of cell types, including vascular cells, is stromal-derived factor 1 (SDF-1), which, through interaction with its receptor CXCR4 expressed on PCs, modulates PC role in angiogenesis. A key mediator of SDF-1/CXCR4 axis is Cyclophilin A (CyPA). Specifically, CyPA binds to CXCR4 and modulates SDF-1-mediated chemotactic cell migration. Further, CyPA has been shown to enhance endothelial cell (EC) proliferation as well as capillary-like structure development and migration.  Importantly, our published data show that CyPA is crucial for the mobilization and recruitment of bone marrow (BM)-derived cells in the diseased aorta of ApoE-/- mice. However, CyPA role in PC function is unknown. Based on experimental evidences underlying the importance of CyPA in SDF-1/CXCR4 axis, ability to modulate EC function in vitro, and BM cell mobilization or recruitment, this proposal aims at evaluating the role of CyPA in new blood vesse
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Humidity-Tolerant Adsorbents for CO2 Capture without Gas Pre-Drying' to be submitted under Horizon Europe.

assistant: **Abstract**

WETCAP builds on a recent breakthrough: the discovery of MUV-92, a pyrazolate-based ultramicroporous Metal-Organic Framework that efficiently captures CO2 even under very humid conditions, where existing sorbents typically fail. This Proof of Concept project aims to turn MUV-92 from a laboratory discovery into a market-ready solution for decentralized applications such as biogas upgrading, fermentation off-gases, and small-scale industrial flue gas treatment.The project will secure intellectual property and define an exploitation pathway by combining licensing to industrial partners with early-stage commercialization mechanisms. MUV-92 will be scaled up to kilogram production and shaped into mechanically robust beads compatible with industrial Pressure/Vacuum Swing Adsorption (PSA/VSA) systems, and its performance validated under demanding high-humidity and contaminant-rich gas streams, including long-term stability testing.To ensure market relevance, technical validation will be complemented with cost benchmarking, external market studies, and close interaction with industrial partners providing pilot plants in Spain for future demonstrations. Strategic mentorship from specialized consultancy firms will reinforce the commercial vision and exploitation plans.By bridging advanced materials research with real industrial needs, WETCAP will demonstrate the feasibility of MUV-92 as a competitive CO2 capture solution and lay the foundations for larger-scale initiatives, including a follow-up EIC Transition towards pilot deployment and early market adoption.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Cellular pathways determining growth and human brain size' (HUMGENSIZE).

assistant: **Innovation**

The greatest differences between mammals are size. As well, the large evolutionary expansion of the cerebral cortex is a defining feature humans. Despite this, much remains to be learnt about the developmental and evolutionary factors controlling organ and organism size. This is in marked contrast to the exquisite detail in which developmental patterning has been defined in model organisms.  The identification of genes for human disorders of extreme growth failure (microcephalic primordial dwarfism) provides a means to gain new insights into the regulation of human brain and body size. I have identified eight genes regulating cerebral cortex volume and organism size, all of which encode fundamental components of cell machinery regulating cell division. This proposal aims to ascertain the genes causing the other 85% of primordial dwarfism, and define their cellular and developmental functions.  The central hypothesis for the proposed work is that such primordial dwarfism and microcephaly genes are components of common cellular pathway(s) relevant to organ and organism growth. I propose to pursue complementary approaches involving human disease gene identification, cell biology studies, and model organisms, to address this hypothesis and further define the pathogenesis of these conditions.  These cross-disciplinary studies will contribute to our understanding of vertebrate growth regulation and help us understand how the human brain evolved. They may provide insights into neural stem cell division relevant to brain repair. Finally and not least, regulation of DNA replication, centrosome function and DNA damage response signalling are key cellular processes perturbed in many important human diseases, from developmental disorders to cancer.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Coordination of International Research Cooperation on soil CArbon Sequestration in Agriculture' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Targeting ambitious changes in agricultural practices that would preserve restore and enhance soil carbon and soil health requires an increased coordination of international research cooperation. The specific challenge lies in the identification, implementation and verification of agricultural soil management practices  which create a positive soil/ecosystem carbon budget at the farm and landscape levels, sequester carbon, improve soil structure and soil quality and provide climate change adaptation while contributing to sustainable development. In this context, the CSA CIRCASA has an overarching goal to develop synergies on research in this field at European Union and global level, targeting four realistic and highly complementary objectives:O1. Strengthen the international research community on agricultural soil carbon sequestration;O2. Provide an improved understanding of agricultural soil carbon sequestration and its potential for climate change mitigation and adaptation and for demands of increased food production;O3. Synthesizing stakeholder’s views and knowledge needs on agricultural soil carbon sequestration and climate changeO4. Favor a more structured approach, by preparing an International Research Consortium (IRC)These four objectives will produce measurable outputs during the time frame of the project and create significant outcomes for the implementation of the UN Sustainable Development Goals (SDGs) and of the Paris agreement (COP21, 4 per 1000 voluntary initiative) of the UN Framework Convention on Climate Change (UNFCCC). CIRCASA will benefit from the participation of three major initiatives: the Global Research Alliance on agricultural greenhouse gases (GRA), the Joint Programming Initiative on Sustainable Agriculture, Food Security and Climate Change
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'dynamic FEATure sensing in Self-Educating Neural Signal Entities' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

FEATSENSE intends to bring a conceptually novel AI-technology platform based on the results of the FET Open project ph-coding into a commercial environment. To achieve this goal, the FEATSENSE project will work to; (1) understand the current AI market structure, (2) identify the potentially most fruitful developmental adaptations of our technology, (3) develop a company business strategy and plan, (4) establish benchmarks and develop demonstrators showing the strength of our technology, and (5) establish and identify key partnerships and customers within the industry.


**Keywords:** Artificial intelligence, computational architecture, neuroscience, sensing, information processing, autonomous systems