RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Integrating Graphene Devices'.

assistant: **Innovation**

Technology requirements for future IC systems include low power computing and communication, sensing capabilities and energy harvesting. These will unlikely be met with silicon technology alone. The proposed research therefore investigates graphene as a potential alternative technology and contributes to bridging the “valley of death” in innovation that is all too present in Europe. In detail, the proposal focuses on the experimental exploration of novel (opto-) electronic devices and systems based on graphene. Strong emphasis is put on integration, defined as an interdisciplinary approach combining graphene manufacturing, graphene process technology, device engineering and -physics as well as system design. This kind of approach is urgently needed in order to open new horizons for graphene, because it enables a transition from fascinating science to a realistic demonstration of graphene’s application potential in electronics and optoelectronics. The first requirement for the applicability of graphene in ICT is a scalable graphene fabrication technology that can be co-integrated with silicon. The second logical aspect to be investigated is the intricate relationship between process technology and graphene device performance. The third aspect to be considered when discussing integration is how devices can be integrated in existing or future systems, including questions of circuit design. Will graphene systems outperform existing solutions and thus replace them? Will new functionalities emerge and generate novel applications? Hence, the key objectives of this proposal are: 1) a scalable, CMOS compatible large area fabrication technology for graphene and graphene devices, 2) demonstration and assessment of performance advantages and new functionalities of RF graphene devic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Shifting political power: the nature and consequences of distributed renewable energy transitions' in the context of a Horizon 2020 call.

assistant: **Objectives**

Global energy transitions are progressing rapidly. Over half of new generation capacity in 2014 came from renewable energy. Individual, community and co-operative decentralized renewable energy (DRE) producers are capturing a growing share of energy markets (e.g. solar, wind, biomass). As their market share increases, DRE producers are becoming increasingly effective political actors. The traditional political privilege enjoyed by incumbent industries is challenged by these DRE actors as they shift control over jobs, economic growth and energy supplies. Political struggles between competing interests are increasing. However, the nature and extent of these power shifts (e.g. changes in access to policy makers, media influence), and their consequences for political systems and their outcomes (e.g. contested carbon targets, renewable energy subsidies) are poorly understood. This project addresses how and why DRE transitions are shifting political power relations, and the consequences of those shifts for political systems and outcomes. Using an interdisciplinary approach grounded in theory on sustainability transitions (i.e. Multi-Level Perspective), power (e.g. Lukes, Foucault) and institutions (i.e. institutional logics) the project will: (1) examine the conditions leading to shifts in political power by analyzing existing political power relations in regimes where DRE transitions are expected, occurring, or stalled; (2) assess the mechanisms by which political power shifts resulting from these DRE transitions are occurring; and, (3) identify the consequences of DRE-related political power shifts for political systems and their outcomes. Objectives will be explored using a global survey of 20 DRE regimes. Survey insights will be expanded in 5 international comparative cas
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Magnetostrophic Flow in Experiments and the Core of the Earth' (MFECE), addressing dissemination and exploitation.

assistant: **Impact**

We describe here an innovative strategy for understanding the so-called magnetostrophic regime of fluid flow in the Earth s core, and thus the mechanisms by which the Earth s magnetic field is sustained over time. The magnetostrophic regime is the state in which Lorentz (magnetic) forces are balanced by Coriolis (rotational) forces and pressure gradients and is thought to be the zeroth order force balance in the core. We propose a series of ground-breaking experiments using liquid sodium contained in a rapidly rotating sphere containing a differentially rotating solid inner sphere. For the first time electric current is injected into the fluid in different configurations in order that the Lorentz force is everywhere significant. Various other magnetic fields can be applied from the exterior and the interior. The influence of turbulence, viscous and magnetic boundary layers will be examined. The presence of instabilities and wave motion will be studied, and the existence of steady solutions will be naturally determined. Diagnostic measurements of magnetic fields and electrical potentials, and Doppler velocimetry will characterise the experiment. These unique experiments are backed by numerical calculations. Complementary studies will analyse the observed magnetic field over the last 400 years in the same magnetostrophic framework. An inverse method will be developed to find the initial state of the field that evolves in a manner compatible with observations. This will elucidate the interior structure of the magnetic field for the first time, determining the amplitude and morphology of the field. The importance of magnetic diffusion (Joule heating) will arise naturally, and fluid motion in the entire core will be found, allowing comparison with geodetic observations.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Airway Disease PRedicting Outcomes through Patient Specific Computational Modelling' to be submitted under Seventh Framework.

assistant: **Abstract**

The airways diseases asthma and chronic obstructive pulmonary disease affect over 400 million people world-wide and cause considerable morbidity and mortality. Airways disease costs the European Union in excess of €56 billion per annum. Current therapies are inadequate and we do not have sufficient tools to predict disease progression or response to current or future therapies. Our consortium, Airway Disease PRedicting Outcomes through Patient Specific Computational Modelling (AirPROM), brings together the exisiting clinical consortia (EvA FP7, U-BIOPRED IMI and BTS Severe Asthma), and expertise in physiology, radiology, image analysis, bioengineering, data harmonization, data security and ethics, computational modeling and systems biology. We shall develop an integrated multi-scale model building upon existing models. This airway model will be comprised of an integrated 'micro-scale' and 'macro-scale' airway model informed and validated by 'omic data and ex vivo models at the genome-transcriptome-cell-tissue scale and by CT and functional MRI imaging coupled to detailed physiology at the tissue-organ scale utilising Europe's largest airway disease cohort. Validation will be undertaken cross-sectionally, following interventions and after longitudinal follow-up to incorporate both spatial and temporal dimensions. AirPROM has a comprehensive data management platform and a well-developed ethico-legal framework. Critically, AirPROM has an extensive exploitation plan, involving at its inception and throughout its evolution those that will 'develop' and 'use' the technologies emerging from this project. AirPROM therefore will bridge the critical gaps in our clinical management of airways disease, by providing validated models to predict disease progression and response to tre
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Redefining language as an emergent function of the connected brain' under Horizon Europe.

assistant: **Concept**

The traditional view of language as relying on isolated brain areas is increasingly challenged by clinical and anatomical evidence suggesting that it emerges from the dynamic interplay of distributed neural networks across cortical, subcortical, and white matter systems. Despite language’s centrality to human cognition, a unified anatomical model integrating structural, functional, and neurochemical foundations remains absent—limiting progress in our fundamental understanding and clinical translation of research results. The overarching goal of EMERGENCE is to uncover the anatomical principles underlying how language emerges in the brain—molecularly, structurally, functionally, computationally, and clinically—while centring the multimodal integration at the heart of the investigation. Using advanced neuroimaging, computational modelling, behavioural analysis, and clinical investigations it will: (1) map multimodal language networks, highlighting subcortical structures and neurotransmitter contributions; (2) construct the language connectome by integrating structural connectivity and cognitive correlations with a data-driven functional analysis; (3) deliver the first functional white matter atlas of language by exploring the structural-functional basis of five experimental linguistic tasks; and (4) investigate underexplored features such as prosody and phenomena like “clicks” and the selective loss of clicks (aclickia) in African languages, integrating them into a unified brain-cognition model.The project will redefine the neurobiology of language, offering actionable insights for diagnostics, neurosurgical precision, and inform novel interventions. By embracing linguistic diversity and bridging fundamental science with clinical applications, it promises to reshape our u
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'MYA, the innovative diagnostics platform for the full mapping of personal allergies' under Horizon 2020.

assistant: **Concept**

Allergies are chronic conditions caused by an extreme immune response to inhalant and food allergens that affect today 500 million (M) individuals worldwide and 150 M in Europe. International institutions all agree in the benefits that early allergy diagnosis and targeted treatment could bring to society. However, only 5% of the population gets a proper diagnosis, either due to limited awareness or scarcity of allergy specialists. Thus, patients try to self-manage their condition and non-specialists prescribe inadequate treatments. Therefore, the patient’s quality of life could be improved if allergy diagnosis were made accessible to the general public. Also, € 30 M/year would be saved in Europe by enhancing the efficiency of our healthcare system.In response, ALLTOX has created MYA (Map Your Allergies), a high quality, cost-effective test for allergy screening. Our 40-plex array-based technology will serve to quantitatively detect the patient’s immunoglobulin IgE, which are produced by the immune system upon contact with a particular allergen. The personal allergy profile can be obtained and thus, facilitate an adequate management.MYA will be offered to the general public at an affordable price through a network of pharmacies and primary care centres, who will collect the sample and ship it to our selected laboratories to run the analysis. In only 3 days, a full report and personalized advice will be conveniently available to the patient through our website, greatly reducing the current time-to-diagnosis (8 weeks).Our product entails a cost-effective diagnostic test that will facilitate detection of allergy risk and provision of adequate management to those patients suffering from this chronic disease. Also, the MYA test will help to relieve the costly impact incurred
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Bacterial host cell death modulators – a genetic approach to identify anti-apoptotic factors of Chlamydia trachomatis and to explore their role during infection' (GENCHLADEATH).

assistant: **Concept**

Chlamydia trachomatis is a leading cause of sexually transmitted disease - with reported prevalence rates of up to 17% among asymptomatic women in Europe - and as such a frequent cause of infertility. While these bacteria have been known for more than a decade to protect infected cells from apoptosis, the lack of tools for genetic manipulation of chlamydiae significantly hampered the investigation of underlying molecular mechanisms and their role during infection. Yet, the research group of Dr. Valdivia (outgoing host) has recently established a unique system to perform forward genetics in chlamydiae, and in course of the proposed project Dr. Sixt (the fellow candidate) will be among the first researchers able to learn and exploit these techniques. In this process, she will first recover mutant C. trachomatis strains that display a reduced potential to block apoptosis. This will subsequently enable her to identify bacterial anti-apoptotic factors and to study the significance of Chlamydia-mediated cell death modulation in a murine infection model. Finally, she will assess the effect of interference with the anti-apoptotic trait on the immunogenic potential of dying host cells, based on the detection of specific cellular “immunogenicity predictors” that were recently identified by the group of Dr. Kroemer (European return host). This multidisciplinary investigation will provide invaluable insights into chlamydial virulence and will help to predict whether the anti-apoptotic trait may be a potential new drug target. The project offers Dr. Sixt extensive training that is highly complementary to her previous research experiences. The acquired skills, international experience, and newly established contacts will place her in an excellent position to take a leading role in th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Transnational Force of Law' (TFL) under Horizon 2020.

assistant: **Objectives**

Global law is changing fundamentally. New forms of law creation, new modes of adjudication, and new enforcement mechanisms in the transnational constellation challenge our understanding of law as a state-based phenomenon. The attending boom in research on transnational law has significantly contributed to our understanding of its structure and functioning. However, existing normative accounts of transnational law often still rely on a conception of legal force that originates in the state or a polity. As a result, a distinctive and compelling normative theory of transnational law has yet to be realized.TFL will fill this gap by developing a normative theory of transnational law based on a novel concept of the transnational force of law. This concept has two dimensions: In a descriptive sense, the transnational force of law accounts for the plurality of societal legal forces in the transnational legal arena, beyond public/private and state/non-state dichotomies. In its normative dimension, it requires a sophisticated normative foundation for all of these societal legal forces that takes into account polycentric claims for legitimacy, efficiency, and justice. This is what our normative theory of transnational law will provide.This theory will be operationalized in three case studies on areas of transnational law where new forms of rulemaking coincide with a broad societal discussion on their normative foundation: financial markets (lex financiaria), internet governance (lex digitalis), and agricultural markets (lex agraria). The analysis will proceed in two steps: (1) descriptively, systemizing the respective transnational legal phenomena in terms of legislative, judicial, executive transnational legal forces, and identifying normative conflicts with human, societal and e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Exploiting vulnerabilities in protein synthesis for cancer diagnosis and therapy', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Tumor growth requires continuous synthesis of proteins, nucleic acids and lipids that are important components of the cell. Demand for amino acids as the building blocks for protein synthesis in rapidly dividing tumor cells is often much higher than that of normal cells. Such increased demand can represent a vulnerability of the tumor. Importantly, this vulnerability is already being exploited for therapy in one instance: Addition of L-asparginase - an enzyme lowering the concentration of the amino acid asparagine in blood - to chemotherapy against acute lymphoblastic leukemia, resulted in a dramatic increase in cure from 5% to 95% of patients treated. Recent scientific publications highlight the fact that tumors are often metabolically rewired, and multiple examples of altered amino acid demand and/or turnover have been demonstrated in different cancer indications. Multiple drugs are under development that target amino acid availability, uptake or biosynthesis.The challenge is to identify the potential sensitivity of individual tumors to such drugs.Recently, we developed diricore, a procedure for determination of restrictions in the availability of particular amino acids for protein synthesis. To demonstrate the potential for diricore’s diagnosis capability in cancer, revealing proline limitations for protein synthesis in kidney cancer.  We also used kidney cancer cell lines to verify sensitivity to proline deprivation, suggesting therapeutic possibilities. We propose here to develop diricore towards a commercial diagnostic platform for determining limiting amino acid availability profiles in cancer patients. This information will guide physicians in taking dietary measures or prescribing drugs that inhibit amino acid uptake or biosynthesis.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The role of the civil society in the EU member states and candidate countries: where does Turkey stand in the general picture?' (TURKEY-EU) under Sixth Framework.

assistant: **Objectives**

The particular differences of political culture in the EU between the member-states and the member and the candidate countries impede the deepening of the European integration.For most of the recent member and current candidate countries the long years of Communist rule resulted in a political culture divergent from that of Western Europe, emphasising institutional control rather than popular participation. Decades of ethnic conflict and religious clashes in the Balkans furthered the different understandings about the individual-state relations in the Southeastern Europe.In the case of Turkey, creating a secular state in an essentially Muslim country posed yet another challenge. Given the plethora of challenges, the rapid inclusion of citizens into the integration process is extremely difficult as the different political cultures of member states and member and candidate countries allow for rapid integration at the elite level.This in turn tends to alienate the masses from the supranational political processes. In this context, this research project intends to shed light on these challenges by exemplifying various examples of civil society development in the EU. Research Objectives: To ascertain to what extent the civil society is active in political life in the selected West and East European countries.Who are the major actors in the development of policies at national and supranational levels? (national or Euro-bureaucracy, political actors or national and supranational NGOs?). To analyse the main activities of the EU with regards to the development of civil society in the member and candidate countries.To investigate the level of civil society development in Turkey. What are the recent developments in the country with regards to the civic initiatives? How does the sp