RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'How Can “Images Drive Out Images”? The Use and Function of Devotional Imagery in Heinrich Seuse’s Exemplar: A Reassessment' in the context of a Seventh Framework call.

assistant: **Objectives**

The aim of this research and training programme is to provide new answers to art historical questions on the use and function of images in the meditative practices of the Late Middle Ages. I will do this by focusing on the highly problematic case of Heinrich Seuse’s Exemplar in an interdisciplinary way, combining Visual and Textual studies. For this reason I am applying to Leiden University Institute for Cultural Disciplines, which hosts a research group working on the mystical tradition of the Rhineland an the Low Countries (the Initial Training Network ""Mobility of Ideas and Transmission of Texts"") and where, as an art historian, I will gain training in the fields of Medieval Textual studies and Manuscripts studies.Heinrich Seuse (†1366) was one of the most influential mystic writers in the Rhineland during the Middle Ages. In the Exemplar (a compilation of his texts accompanied by drawings he designed) Seuse offers a complex example of the relationship between text and images in the spiritual realm and a theory of devotional imagery based on a key phrase: “Drive out images with images”. Oft-quoted, but generally misunderstood, this concept needs to be reassessed in order to fully understand Seuse’s conception of devotional imagery. Scholars often state that for medieval mystics, images were important at the beginning of the meditative process but that they were simply tools to be left behind in order to move beyond the sensory world. Yet, with this phrase, Seuse offers a more subtle vision of this process: images should not be dispensed with entirely, instead each image must be replaced by another so that they complete and correct each other. This idea of continual interchanging modifies our understanding of the contemplative theory of the Exemplar. During this fel
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'System for AcceleroMeter-Based Assessment of cardiac FUNction' (SAMBAfun) under Horizon 2020.

assistant: **Objectives**

In patients undergoing open-heart surgeries, perioperative cardiac monitoring is used to track the functioning of the heart and identify complications. However, myocardial failure and other severe complications can escape detection using current monitoring technologies, given the trade-offs between invasiveness, real time measurements, accessibility and accuracy of data. Given the high-risk profile of these surgeries, failure to timely detect complications leads to increased mortality and morbidity, which in turn results in increased hospitalization costs and lower quality of life for the affected patients. For effective cardiac monitoring, surgeons need real time data, 24h continuous monitoring during and post-surgery, and an accurate biosignal marker that can be trusted for immediate detection and assessment of cardiac events. No current technology enables this with low invasiveness and risk.Cardiaccs (SME) and Osypka (SME) will bring to market a patented solution that involves adding a 3-axis accelerometer to a standard epicardial pace lead, which is routinely used for most cardiac surgical patients, to assess cardiac motion and contractility in real time, both during and after surgery – and up to 7 days. Data from CardiSense will appear on a monitor and an alert function will let surgeons and nurses know as soon as a complication is picked-up on the continuously analysed data.SAMBAfun brings together 2 SMEs with complementary know-how, IPR and value chain positions. Cardiaccs patented the concept, whereas Osypka has 40 years of experience in developing cardiac pace leads. Osypka dominates the German market and has extensive ties to global distributors. Three leading research hospitals (Oslo, Aarhus and Berlin) will demonstrate the latest advances in this device, pro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Construction companies processes re-engineering' (CORE) under Fourth Framework.

assistant: **Objectives**

The CORE project aims to carry out comprehensive transformations of important business processes within two European construction companies (one large, one small) and to derive generic structures that can be used throughout the industry.The process redesign will include all levels, from a strategic planning level to the tactical process management level and to the details of carrying out the process steps, including the process implementation. CORE will develop goals, metrics and assessment procedures for construction-industry business processes. A prototype of the IT structure to support the business processes will be developed. The project will show how to implement the new processes and how to manage and gradually improve them. It will disseminate the results and experiences to enable other companies to carry out similar projects.The project concentrates on four specific business processes, namely tendering, technical planning, purchasing and economical planning and control. The results of the project will be used directly in the two end-users, thus making it possible to validate that the results of the project are applicable in different countries and in different types of company.CORE will be carried out according to a procedural model that includes the stages of detailed process understanding, process structuring and process changing. The project will use state-of-the-art process re-engineering tools and methods. The improved processes will be used for creating reference models containing generic structures for use within the entire industry.These computer-based reference-models and the process-oriented adaptations of information systems for the construction industry will be marketed by the software vendors in the Consortium.CORE brings together two leading constr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Antiseptics and disinfectants - evaluation of standardized procedures aimed at activity testing'.

assistant: **Concept**

Chemical disinfectants and antiseptics are used as aids in the prevention of cross-infection in a wide variety of areas and for a broad range of applications. In the project of European Directive on Biocidal Products, efficacy data of disinfectants are required for placing these products on the market. The annex Vl of this project of Directive specifies that these efficacy data can be established by using European Standards. However the present standards (EN 1275, EN 1276 and Pr EN 1657) dealing with test methods for the evaluation of anti-microbial activity of disinfectants and antiseptics prepared by CEN/TC 216 << Chemical disinfectants and antiseptics )) are the result of compromises between the different experiences gained by some European countries through their national standardization and require some research and validation in order to make sure that they can really serve as reference documents for application of the Directive. Indeed, for example: - EN 1275, EN 1276 and Pr EN 1657 propose two alternative methods: thedilution-neutralization method and the membrane filtration method while noextensive comparison between the alternative methods, when used in theconditions stated by the standards, exist. In addition, an alternativemethod combining neutralization and membrane filtration has recently beenproposed and may be suitable in order to avoid some limits of the membranefiltration method as described in the current standards, - In Pr EN 1657, two alternative counting techniques are proposed (the pourplate technique and the spread plate technique) and again no comparisonexists between them in the condition stated in the standard, - In the three standards a range for the initial count of extensive strainsis given but its method of determination is left open. This
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Advanced Research and eXploration for Interoperable Value in European Heritage' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

ARXIVE revolutionizes the documentation, analysis, and dissemination of cultural heritage objects by developing cutting-edge tools and methodologies integrated into the European Collaborative Cloud for Cultural Heritage. Addressing fragmented on-site workflows and the challenges of preserving both tangible and intangible cultural assets, ARXIVE introduces a semantic archival system that provides advanced solutions for annotating evolving digital twins. These tools empower cultural heritage professionals to create semantically rich, context-aware documentation while streamlining processes for research, preservation, and dissemination. The project enhances the accessibility, organization, and contextualization of cultural heritage objects by integrating high-fidelity 3D reconstructions, granular annotations, AI-powered annotated bibliography tools, and narrative-building applications. It ensures interoperability with established standards principles, fostering seamless collaboration and long-term sustainability. Through two Use-Case Pilots (Greece and Portugal) the tools will be tested and validated in real-world environment, a through  a comprehensive Financial Support to Third Parties program to funding and accelerating at least twenty projects via two diverse Open Calls, ARXIVE will engage different stakeholders, promote knowledge sharing and capacity building, and foster the scalability and wider adoption of ECCCH tools. Leveraging the expertise of a multidisciplinary consortium of nine partners from five countries, ARXIVE establishes strong synergies with ECCCH initiatives to amplify the impact of European cultural heritage. By advancing cutting-edge methodologies and fostering collaboration, ARXIVE positions European heritage at the forefront of innovation, ensuring
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Elucidation of intratumoral heterogeneity in Kras-driven cancers' in the context of a Horizon 2020 call.

assistant: **Objectives**

The considerable variability within tissue microenvironments as well as the multiclonality of cancers leads to intratumoral heterogeneity. This increases the probablility of cellular states that promote resistance to therapy and eventually lead to reconstitution of the tumor by treatment-resistant cancer cells, which in some cases have properties of normal tissue stem cells. Wnt signals are important in the maintenance of stem cells in various epithelial tissues, including in lung development and regeneration. We hypothesized that Wnt signals contribute to tumor heterogeneity in genetically engineered KrasG12D; Tp53Δ/Δ (”KP”) mouse lung adenocarcinomas (LUAD). We observed that a subpopulation of LUAD cells exhibited high Wnt reporter activity and had increased tumor forming ability, which could be suppressed by silencing of Wnt signaling pathway components or by small molecule Wnt inhibitors in vitro and in vivo. KP LUAD cells show hierarchical features with two distinct populations, one with increased Wnt reporter activity and another forming a niche that provides the Wnt signal. Lineage-tracing experiments in the autochthonous KP tumors demonstrated that Wnt responder cells have increased tumor propagation ability in vivo. Strikingly, selective ablation of the Wnt responder cells resulted in tumor stasis. CRISPR-based targeting or small molecules targeting Wnt signaling reduced tumor growth and prolonged survival in the autochthonous KP mouse lung cancer model. These results indicate that maintenance of heterogeneity within tumors may be advantageous for the tumor cell population collectively. We propose to elucidate the molecular and cellullar mechanisms that control stem-like and niche cell phenotypes using a combination of novel lentiviral vectors and genetically m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Runtime Exploitation of Application Dynamism for Energy-efficient eXascale computing' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

High Performance Computing (HPC) has become a major instrument for many scientific and industrial fields to generate new insights and product developments. There is a continuous demand for growing compute power, leading to a constant increase in system size and complexity. Efficiently utilizing the resources provided on Exascale systems will be a challenging task, potentially causing a large amount of underutilized resources and wasted energy. Parameters for adjusting the system to application requirements exist both on the hardware and on the system software level but are mostly unused today. Moreover, accelerators and co-processors offer a significant performance improvement at the cost of increased overhead, e.g., for data-transfers.While HPC applications are usually highly compute intensive, they also exhibit a large degree of dynamic behaviour, e.g., the alternation between communication phases and compute kernels. Manually detecting and leveraging this dynamism to improve energy-efficiency is a tedious task that is commonly neglected by developers. However, using an automatic optimization approach, application dynamism can be detected at design-time and used to generate optimized system configurations. A light-weight run-time system will then detect this dynamic behaviour in production and switch parameter configurations if beneficial for the performance and energy-efficiency of the application. The READEX project will develop an integrated tool-suite and the READEX Programming Paradigm to exploit application domain knowledge, together achieving an improvement in energy-efficiency of up to 22.5%.Driven by a consortium of European experts from academia, HPC resource providers, and industry, the READEX project will develop a tools-aided methodology to exploit the dy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how '"BioCP-3DInk: Advancing Biocompatible 3D Printing Inks for Next-Generation Applications""""' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The BioCP-3DInk project aspires to bolster the European Research Area (ERA) by creating an innovative breed of conductive ink. This biodegradable, biocompatible, and entirely organic ink uniquely boasts inherent auto-crosslinking capabilityan unparalleled trait in its category. This breakthrough engenders synergistic attributes by amalgamating hydrogel and conjugated polymers (CP), paving the way for developing novel soft and disposable sensors printed electronics.  BioCP-3DInk offers a fresh perspective on this issue by crafting a conjugated polymer that combines thiophene and lactams through imine bonds, enhanced with acrylate functionalization. Distinguishing itself from existing inks, BioCP-3DInk stands out as the first ink i) based on biocompatible and biodegradable CP (undergoing lactam and imine hydrolysis) and ii) capable of self-crosslinking via DLP 3D printing, utilizing acrylic groups, thereby heralding an innovative breakthrough in the field.This objective delves into innovative avenues to address a paramount challenge of our era: the creation of fully bioabsorbable implantable devices and the mitigation of e-waste pollution. In doing so, we aim to enhance quality of life and advance sustainability globally.


**Keywords:** Conjugated polymer, biodegradable and biocompatible ink, 3D printer, self crosslinker conjugated polymer, soft electronics, sensors
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'NOVEL, SUSTAINABLE MARINE BIO-SURFACTANT / BIO-EMULSIFIERS FOR COMMERCIAL EXPLOITATION' (MARISURF) targeting Horizon 2020.

assistant: **Abstract**

Surfactants and emulsifiers constitute an important class of chemical agents that are widely used in almost every sector of modern industry. The huge market demand is currently met almost exclusively by synthetic, mainly petroleum-based, chemical products, which are usually non-biodegradable and mostly toxic or GM plant based products (used in foods), which are undesirable by some end-users. Their biologically produced counterparts (i.e. bio-surfactants and bio-emulsifiers) offer more green sustainable alternatives. This has led to a number of manufactures, looking for ways to increase competitiveness through searching for underexploited sources such as the marine environment. Our objectives are to develop (1) innovative approaches in discovering, characterizing and producing novel marine-derived bio-surfactants from a large bacterial collection (greater than 500 strains) housed at Heriot Watt University, originally isolated from various coastal and open ocean waters around the world, (2) novel, economic, and eco-friendly end-products with commercial applications in order to replace synthetic counterparts, and (3) to demonstrate the functionality of new product development for commercial exploitation. Our collection consists of novel bacterial species, originally isolated for their ability to degrade oils, with proven promise in this respect. For this reason, our consortium (consisting of academic institutions, industrial companies and end-users) offering a wide range of expertise, will address the technical bottlenecks for meeting our objectives, namely those of marine resource identification, sustainable supply, discovery pipeline and efficient production in biological systems. The relevance of our proposal to the work programme is underlined by its expected impact in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Constellation optimization for continuous variable QKD' to be submitted under Horizon Europe.

assistant: **Abstract**

In today's highly interconnected world, secure communication between distant parties is paramount. Quantum Key Distribution (QKD) protocols, rooted in quantum mechanics, offer a promising solution to this challenge by ensuring the generation of secure keys with high data exchange rates. This project objectives seek to advance the state of secure data exchange by optimizing quantum state transmission within QKD protocols. Focusing on Continuous Variable QKD (CV-QKD), we aim to pioneer novel algorithms that not only bolster security but also enhance cryptographic system efficiency. By shaping constellations and fortifying security proofs, COCoVaQ provides imperative contributions for secure communication, safeguarding sensitive digital information.Currently, state-of-the-art CV-QKD protocols lack the sophisticated tools developed within the scope of optical communication systems, such as adaptive methods for optimal constellation optimization, which enable the transmission of secret keys at a high rate. Additionally, existing security analyses of CV QKD protocols with practical, discrete modulation often overlook critical symmetry aspects of the transmission algorithms that are imperative to establish security against arbitrary attacks.In response, our project endeavors to devise groundbreaking algorithms for constellation shaping and introduce symmetry properties to CV-QKD protocols employing discrete modulation with provable security. Notably, discrete modulation typically results in a substantial penalty on the resilience against attacks. With the aid of constellation optimization, this project aims at mitigating this penalty by between 10 and 20 orders of magnitude, ensuring a theoretically secure exchange of secret keys of high rate at long distances. Finally, COCoVa