RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'A novel multi-functional elastin-like recombinant hydrogel for the prevention of scar tissue formation following a myocardial infarction: ""ELR-SCAR""""' (ELR-SCAR) targeting Horizon Europe.

assistant: **Abstract**

The ELR SCAR project aims to complete preclinical validation of a novel biomaterial, an elastin-like recombinant (ELR) hydrogel, to prevent scar tissue formation in the heart following myocardial infarction (MI), commonly called a heart attack. MI is the endpoint of ischaemic heart disease (IHD). In Europe, the highest rates of IHD worldwide equal ~26.5 million patients. Standards of care interventions after MI have serious limitations in treatment efficacy (many patients are still at risk of developing heart failure) and patient safety. There is a clear medical need for new treatment solutions that prevent scar tissue formation and irreversible cardiac remodelling. Our robust preclinical dataset so far indicates that the ELR hydrogel has this promising functionality via multiple unique characteristics: it provides selective cell adhesion to the endocardium, providing a barrier to scar tissue formation; it offers high biospecificity to the ischaemic microenvironment, and it has an enhanced biodegradability, allowing for safe disintegration in the body. To facilitate endocardial delivery of the ELR hydrogel, we will develop a minimally invasive endocardial catheter in this project. Both components (hydrogel + catheter) will be advanced to the preparedness level for a first-in-human (FIH) validation study for the application as therapeutic intervention post-MI (to be performed after the project). In addition, we will develop the regulatory and IPR strategies in preparation for this clinical validation step. Considering the high societal impact of ischaemic heart disease (IHD) and MI, we will also develop a solid health economic evaluation of possible savings and patient benefits. ELR-SCAR will transform and fundamentally improve clinical practice, resulting in reducing th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'European Arthurs, Medieval To Modern' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

European Arthurs, Medieval to Modern’ (EUARTHURS) examines, for the first time, in cross-cultural synchronic and diachronic ways, the conceptualisation and the transmission of Arthurian matter in its move from its origins in early medieval narratives from Wales into other geographical and linguistic areas in Europe in the Middle Ages, into other genres and art forms that endure to the present day. Starting from the dichotomy that used to be perceived, in modern scholarship, between ‘centres’ of cultural power and diverse regional ‘peripheries’,  EUARTHURS problematises both medieval and modern academic definitions of where the centre or centres were (and are) of this best-selling tradition in the Middle Ages, and explores their constant re-invention in traditions seen for far too long as ‘peripheral’ in European medieval writing and art, then in post-medieval forms. Supported by a team of non-academic partners, including repository libraries, archives, museums, and publishers, as well as creative environments, EUARTHURS aims to demonstrate that the culturally- and politically-specific environment which framed the appearance and then the dissemination of Arthurian legends across Europe shaped the key elements in these stories that led to the endurance of this global cultural export from then on and to the present day. The very academic tradition functions as an obstacle when it comes to examining how texts travelled across linguistic borders and what happened/still happens to them when they do. This is why we need EUARTHURS, as a ground-breaking cross-linguistic, comparative, cross-period project that trains the next generation of researchers to understand global movements of cultural texts and artefacts and how some texts go ‘viral’ while others are marginalised. EUARTH
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Observation-based system for monitoring and verification of greenhouse gases' to be submitted under Horizon 2020.

assistant: **Abstract**

As the negative impacts of rising global temperatures become increasingly evident, national governments, regional authorities and private stakeholders are enhancing efforts to curve down the emissions the greenhouse gases (GHG) responsible for global warming. Measuring the effectiveness of GHG emission reduction policies against agreed-upon international targets require accurate and precise estimates of emissions and their trends. These estimates need to be established and regularly updated using transparent methods, tracable to international standards. VERIFY proposes to quantify more accurately carbon stocks and the fluxes of carbon dioxide (CO2), methane (CH4), and nitrous oxide (N2O) across the EU based on independent observations in support of inventories that rely only on statistical data.  The same approach will also be tested for US, China and Indonesia, in collaboration with foreign partnes. Accurate characterization of the space-time variations of GHG fluxes, separating their anthropogenic and natural components and their drivers, will be based on advanced modelling approaches using atmospheric GHG measurements, tracer transport inversions and various arrays of land observations, in-situ and from space. The improved knowledge of GHG budgets from VERIFY will be used to improve national inventories, in collaboration with national inventory agencies, and to deliver policy-relevant information to track progress of the EU mitigation efforts to meet the targets of the Paris Agreement on Climate, in line with international cooperation mechanisms promoted by the WMO, the IPCC and the UNFCCC.


**Keywords:** greenhouse gas emissions,  monitoring, reporting and verification (MRV),  national inventories,  ecosystem and atmospheric modelling,  assessment,  tracer transpor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Applications of lightweight sandwich sheets (APOLISS)' (APOLISS) under Fifth Framework.

assistant: **Objectives**

Lightweight materials are a key means to reduce fuel consumption & CO2 emissions. One of the most promising materials are lightweight sandwich sheets which have not been extensively used in vehicle industry, because sufficient methods for mass production have not been developed. Expected results of the project research are advanced lightweight body concepts utilising the potential of sandwich sheets and the related manufacturing and joining technologies applicable for mass production. With an expected weight reduction of 50% in replaced parts major vehicle components can be downsized and this leads to further weight reduction. It is expected to introduce sandwich sheets into production vehicles 1-3 years after the project. The findings will also extend the application of lightweight sandwich sheets in other areas.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'High Integrity Distributed Object-Oriented Realtime Systems' (HIDOORS) under Fifth Framework.

assistant: **Objectives**

Plummeting hardware cost and continued rapid development of integrated circuit technology are leading to an explosion of interest in new applications of distributed, real time, and embedded systems, while the technologies to build reliable and secure software are still inadequate. Java, with its increased development productivity, better code quality, inherent security, and support for distributed computing, would be ideal for this application domain. HIDOORS seeks to overcome the technical difficulties and bring Java to the distributed, real time system domain. These difficulties are predictable automatic memory management and multi-threading, limited system resources(CPU power, memory, etc.), and the lack of adequate development environments and analysis tools.OBJECTIVESThe HIDOORS project aims to enable the use of Java for distributed realtime systems by developing:1) a deterministic implementation of the full Java language;2) a fast deterministic remote access technique for distributed realtime programming;3) modeling tools that facilitate the construction and automatic verification of distributed, realtime, safety-critical systems;4) improving the memory and run-time performance of Java, and;5) integrating the new tools for software analysis and development into an existing common software development environment.DESCRIPTION OF WORKThe work to be performed consists of these main packages1) requirements analysis for time-critical applications for different target domains;2) development of UML modeling tools for distributed, realtime systems to analyse security conditions of the model;3) implementation of a Java runtime system with distributed event management and optimizing compiler for deterministic execution of Java code;4) development of a tool for automatic wors
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'LIght-responsive GrapHene-based inTerfaces for Electrical STimulation' (LIGHTEST) targeting Horizon 2020.

assistant: **Abstract**

Neurological disorders are a global leading medical and societal challenge, affecting particularly the aged population. Because of the lack of efficiency of pharmacological options, alternatives such as electrical stimulation using implanted electrodes has gained popularity. However, this strategy lacks spatiotemporal control over the stimulation of specific neural circuits, of which no biochemical information can be acquired. Recent breakthroughs in non-genetic, light-mediated electrical stimulation have shown promising results towards minimally invasive devices with controllable performance following exposure to near infrared (NIR) light. The LIGHTEST project proposes an innovative neural interface constituted by electrodes combining graphene with upconversion nanoparticles (UCNP), which will convert NIR light into electricity with spatiotemporal control. We will use novel tools to screen formulated graphene-UCNP complexes and evaluate their biological interactions in the presence of NIR light (e.g. high-throughput screening, RNA sequencing). This project counts on the applicant’s knowledge in synthesis, characterisation and biological evaluation of graphene-based materials, alongside the expertise of Dr Lino Ferreira in the formulation of light-responsive nanomaterials and their in vivo interactions, in combination with the experience in optogenetic engineering and mechanistic understanding of light-mediated stimulation in the brain from Dr João Peça at the Host institute. This project will contribute to the establishment of the applicant in Portugal as an independent researcher in nanomedicine, which is a strategic field that will boost European competitiveness in the development of novel therapies and inspire new generations for a better healthcare.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'CHEmically-mediated MICRobial Interactions maintained by the toxic dinoflagellate OStreopsis cf. ovata' (CHEMICROS).

assistant: **Concept**

Important proliferation of microalgae, the so-called Harmful Algal Blooms (HABs), affects aquatic ecosystems. Extensive repercussions of HABs on human health, aquatic species, and aquaculture are yearly recorded worldwide and related economic losses can be measured in millions of dollars. Given their impacts, the increasing occurrence of HABs worldwide constitutes a major ecological issue for the coming decades. The proposed research project CHEMICROS (CHEmically-mediated MICRobial Interactions maintained by OStreopsis) aims to investigate the three essential aspects of the microbial control of Ostreopsis blooms: (i) influence on the specialized metabolism, (ii) commitment with toxins degradation, and (iii) potentiality as bio-agents for blooms control. The proposed research will benefit from the training offered by two renowned institutions, the Center for Marine Biotechnology and Biomedicine at Scripps Institution of Oceanography (USA, outgoing phase) and the Laboratory of Oceanography of Villefranche-sur-mer (France, incoming phase), whose research activities focus on natural products chemistry and plankton ecology, respectively. A large part of this project relies on the use of cutting-edge techniques in analytical chemistry, for which I will be trained during the outgoing phase. This knowledge will be transferred to the European host by organizing a technical workshop. The multidisciplinary skillset and knowledge developed through the fellowship will help me gain European and international visibility in the field of microbial ecology and will increase my competitiveness and attractiveness for potential collaborations with researchers in academy or industry, as well as with European managers of aquatic environments. The methodologies developed during the fellowship
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Piloting Multi MW Ammonia Ship Fuel Cells', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

ShipFC’s main mission is to prove and show the case for large-scale zero-emission shipping. We do this through developing, piloting and replicating a modular 2MW fuel cell technology using ammonia as fuel. The project will first adapt and scale-up existing fuel cell solutions to a 2MW system, develop ship and land fuel systems for ammonia and integrate the full system onboard a large offshore construction vessel. Then the solution will be validated through commercial operation for at least 3000 hours during a one-year period. Moreover, socio-technical models and analysis will be performed and a full feasibility study on a series of additional vessels will be conducted.


**Keywords:** ammonia zero-emission shipping pilot
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Molecular by-pass therapy for mitochondrial dysfunction' (2007-2013) targeting Seventh Framework.

assistant: **Abstract**

Many eukaryotes, but not the higher metazoans such as vertebrates or arthropods, possess intrinsic by-pass systems that provide alternative routes for electron flow from NADH to oxygen. Whereas the standard mitochondrial OXPHOS system couples electron transport to proton pumping across the inner mitochondrial membrane, creating the proton gradient which is used to drive ATP synthesis and other energy-requiring processes, the by-pass enzymes are non-proton-pumping, and their activity is redox-regulated rather than subject to ATP requirements. My laboratory has engineered two of these by-pass enzymes, the single-subunit NADH dehydrogenase Ndi1p from yeast, and the alternative oxidase AOX from Ciona intestinalis, for expression in Drosophila and mammalian cells. Their expression is benign, and the enzymes appear to be almost inert, except under conditions of redox stress induced by OXPHOS toxins or mutations. The research set out in this proposal will explore the utility of these by-passes for alleviating metabolic stress in the whole organism and in specific tissues, arising from mitochondrial OXPHOS dysfunction. Specifically, I will test the ability of Ndi1p and AOX in Drosophila and in mammalian models to compensate for the toxicity of OXPHOS poisons, to complement disease-equivalent mutations impairing the assembly or function of the OXPHOS system, and to diminish the pathological excess production of reactive oxygen species seen in many neurodegenerative disorders associated with OXPHOS impairment, and under conditions of ischemia-reperfusion. The attenuation of endogenous mitochondrial ROS production by deployment of these by-pass enzymes also offers a novel route to testing the mitochondrial (oxyradical) theory of ageing.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'ORigin and evolutION of biodiversity at the microevolutionary and macroevolutionary scales in swallowtail butterflies', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Patterns of species distribution across space, time, and taxonomic groups have long fascinated scientists. The origins of species diversity lie in speciation events, and uneven species richness is evidence of different rates of speciation. Understanding the drivers of biodiversity has taken two approaches: either focusing on allelic frequency variation and quantitative trait evolution within species (microevolution) or examining speciation rates and phenotypic evolution across species (macroevolution). However, a conceptual gap persists between these fields that questions the ability of microevolutionary processes to explain macroevolutionary rates. The concept of speciation is a critical link between these scales, with population-level processes theoretically influencing macroevolutionary rates. Reconciling micro- and macroevolution has produced conflicting evidence on the relationship between population-level processes and macroevolutionary rates, highlighting the need for further investigation. In this context, the ORION project will bridge the gap between micro- and macroevolution to address a pressing question in biodiversity research: can microevolutionary processes reliably predict macroevolutionary rates? Using a multidisciplinary approach focused on swallowtail butterflies (Papilionidae) – an iconic insect family with well-understood systematics and taxonomy of 640 globally distributed species – we will collect and integrate genomic, phenotypic, and ecological data at both species and subspecies levels. We will test whether population isolation, reproductive isolation, ecological and phenotypic differentiation, and population persistence (microevolutionary processes) play a role in controlling speciation rate and rates of phenotypic and niche evolution (macroev
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Bergen advanced training site in marine ecology' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

Fellows will benefit from an interdisciplinary but coherent scientific environment, and:- World-class expertise in ecological modelling and many of the sub-disciplines involved;- The wide range of the environmental and ecological expertise gives a unique opportunity to study the complexity of marine environmental science, of high value for the doctoral candidate irrespective of whether the future career is in science, management, industry or education - Continued supervision afterwards to ensure high quality of the publications(s) - State-of-the-art installations for laboratory, field work and modelling. Access to all facilities (experimental, vessels, supercomputers) on equal terms with local staff - Own lab-site and a desk with a networking computer - Flexible degree of integration of thesis work to ongoing projects at UoB - Easy to combine experimental, field and modelling approaches - Wide range of courses in marine sciences - Office for Foreign Students helps with accommodation in one of the students hotels - Friendly-sized town of 230.000 inhabitants, 8% study or work at UoB - Close co-operation with Bergen Marine (IHP-Research Infrastructure) .