RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Optical interrogation of the claustrum from synapses to behavior', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

How does the brain integrate inputs from the environment to generate perception and drive decisions? An enigmatic brain region called the claustrum has been suggested to play a role by integrating inputs from multiple brain regions. There is strong interconnectivity between claustrum and nearly every neocortical brain region, indicating that it exerts widespread influence on brain function. However, approaches to specifically record from or manipulate activity in the claustrum have been hindered by the inability to target it selectively. This has been difficult due to the anatomy of the claustrum: it is a long, thin bilateral nucleus buried between the neocortex and the striatum. This proposal aims to understand the role of the claustrum in multisensory integration and behaviour by developing new approaches for monitoring and manipulating the activity of the claustrum. We will harness recent advances in electrophysiological, genetic, optical, and behavioural tools to probe its connectivity, activity, and function in a precise manner. Understanding the role of the claustrum in brain function will provide fundamental insight into information processing in the neocortex, which is a major goal in neuroscience. The claustrum is unique because of its dense reciprocal connectivity with neocortex but nearly complete lack of direct subcortical sensory input. This particular anatomical structure indicates the possibility of a unique function, but none has been observed yet. This proposal will rectify the paucity of data on this distinctive structure by applying a battery of modern tools to address the function of the claustrum. Experiments will address the following key questions:1. How are claustrocortical inputs integrated and what is the effect of corticoclaustral feedback?2.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Indian-Atlantic interocean exchange as modulator of global climate' (INDEXCLIMA), addressing dissemination and exploitation.

assistant: **Impact**

Indian-Atlantic interocean exchange (IAIE), occurring through Agulhas current/leakage, is one of the return flows of global thermohaline circulation that contributes to the temperate climate in Europe. Since IAIE affects the transport of heat and salt to the zone of deep water formation, the variability of Atlantic Meridional Overturning Circulation (AMOC) is related to IAIE as shown by instrumental observation and past reconstructions. However, the relationship between the IAIE and AMOC under different climate conditions including distinct atmospheric CO2 concentration is still to be elusive. The INDEXCLIMA (INDian-Atlantic interocean EXchange as modulator of global CLIMAte) project aims to study the deep-water IAIE, Agulhas current/leakage and AMOC evolution over the last 1000 kyr when internal feedback processes have modified climatic cyclicity from 41 kyr to 100 kyr (Mid-Pleistocene transition) and enhanced the amplitude of interglacial periods (Mid-Brunhes event ca. 430 kyr). The study area is the Mozambique Channel (Indian Ocean) and the Cape Basin (SE Atlantic Ocean) where 3 marine sediment cores were drilled and are available at CEREGE, France. The originality of this project resides on the reconstruction of deep water masses (Nd isotopic compositions, benthic foraminifera) and of surface Agulhas current (planktonic foraminifera) from the same cores across an Indian-Atlantic transect. This will allow estimating lead and lag between Agulhas current/leakage and deep water circulation changes. The study period beyond 800 kyr is also in line with the next target of glaciological community. This project is a great opportunity for me to develop new geochemical and technical skills including mastering Nd isotope geochemistry, the application of an innovative instrument
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'The vascular stem cell niche and the neurovascular unit', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Recent evidence suggests that VEGF and the vasculature play multiple roles in organ homeostasis, functions extending far beyond their traditional roles in tissue perfusion.  The proposed study represents  a vascular-centred approach to  the neurovascular unit thriving to gain further insights on the many ways by which  blood vessels may affect proper brain functioning. Major focus is on the vascular stem cell niche, i.e. the contention that blood vessels are a key component of adult stem cell niches, including a niche securing proper function of neuronal stem cells (NSCs). Further insights on the niche are also critical for contemplated implementation of stem-cell based therapy. In this multidisciplinary study combining the fields of vascular biology, neurobiology, stem cell biology, and aging research, we harness unique transgenic methodologies to conditionally manipulate (via VEGF) the vasculature within the stem cell niches. We provide a first compelling proof that blood vessels at the niche indeed control stem cells properties and behaviour, evidenced by showing that mere expansion of the niche vasculature and independently of VEGF) increases dramatically adult hippocampal neurogenesis, a process known to be associated with improved cognitive performance.  We will determine what aspects of stem cell biology are controlled by juxtaposed, directly contacting blood vessels and will identify signalling systems mediating the vascular/stem cell cross-talk.Adult neurogenesis is known to rapidly decline with age and ways to sustain the process are highly desired. We hypothesize and, in fact, provide initial evidence that expanding and 'rejuvenating' the niche vasculature can override the natural age-dependent decline of adult neurogenesis. Proposed experiments will extend t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Automated quality control system for end products in a textile industry', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The proposed system is designed to: check and identify the end products, (application in a textile industry), comparing the under control product with an ideal one, (the characteristics of which will be recorded to the memory of the computer), and, reject the inappropriate products. The system will consist of an image processing system, to check individually each product, and a system that will reject inappropriate products, indicating the failure points According to the defect point, the product will be placed to the corresponding production stage. The innovation proposed, will be based on modern checking colour-tracing developments, like for example high resolution cameras In addition it is planned to be investigated faster and more reliable systems (by means of high capacity computers on the memory of which will be recorded the data of the ideal product and the data of the product under control), as well as newly developed quick algorithms for image processing The implementation of the proposed system, can lead to optimisation of quality control and productivity, as on the other hand to elimination of the human fatigue factor.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Simplicity and Market Design' (Simplicity) under Horizon 2020.

assistant: **Objectives**

Why are actual contracts and market mechanisms often simpler than our theoretical predictions? This is a central puzzle in microeconomics and, in many environments, it constrains our ability to rely on economic models. It raises further fundamental questions: What does it mean that a contract or a mechanism is simple? How to compare the simplicity of various contracts, mechanisms, and games? The proposed research program aims to address these questions and provide a new behaviorally- grounded foundation for market design, contract theory, and the analysis of simplicity. The program has three complementary parts: (i) to address the simplicity puzzle by developing a novel approach to contracting and mechanism design that takes into account perception errors; (ii) to operationalize what simplicity means and how various mechanisms, contracts, and games can be compared in terms of their simplicity; and (iii) to explore the trade-offs between simplicity and welfare-and-revenue criteria and to develop new practical market mechanisms for markets such as school choice, the assignment of medical transplants, and the auctions of commodities and government securities.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Pushing Quantum Chemistry by Advancing Photoswitchable Catalysis' to be submitted under Horizon 2020.

assistant: **Abstract**

This project exploits the synergy between the trending area of artificial molecular machines and cutting edge computational chemistry approaches. Specific emphasis is placed on photoswitchable catalysts, which respond to external stimuli with a conformational or configurational change. These controllable motions allow catalytic function to be turned ON/OFF in a switch type fashion by opening/hindering access of a substrate to a catalytic site. On one hand, the rich morphology and chemistry of these smart catalysts calls for computational insights and design principles that complement experiment and push the field forward. On the other hand, the inherent complexity of these highly fluxional molecules makes them perfect subjects for driving modern quantum chemistry out of its comfort zone. To benefit from this synergy, the latest innovations in quantum chemistry-based machine learning techniques will be combined with methods capable of thoroughly mapping the intricate chemistry of molecular actuators. Overall, we aim to bridge the gap between the current state-of-the-art, which has reached reasonable quantum chemical accuracy for rigid medium size organic molecules, and more challenging fluxional architectures. The proposed methodological toolbox will be applied to the field of smart catalysis where general strategies for improving the efficiencies and enhancing enantioselectivity will be formulated. Thus, this project involves exploiting a wide range of modern computational approaches to chemical tasks that are broadly relevant to flexible/switchable catalytic systems. The anticipated output will furnish the computational chemistry community with a comprehensive array of novel next-generation approaches with applicability beyond the field of molecular machines.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Polish presidency conference: EU Innovation Journey'25' (EUInnovationJourney) targeting Horizon Europe.

assistant: **Abstract**

The EU Innovation Journey’25 conference, organized under the Polish Presidency of the Council of the European Union, aims to foster an integrated and well-connected deep tech innovation ecosystem in Europe. The event will focus on best practices in supporting deep-tech startups, addressing gaps in technology, business, and investment readiness, and strengthening collaboration between key stakeholders to drive innovation-driven growth.Building upon the New European Innovation Agenda, the conference aligns with the Competitiveness Compass for the EU, reinforcing the strategic direction set by the European Commission to enhance Europe's innovation landscape. The Compass outlines a framework for closing innovation gaps, reducing regulatory barriers, and fostering a more integrated Single Market. It emphasizes access to venture capital, regulatory streamlining, and skills development, essential for enabling startups and scale-ups to thrive.The conference will identify and promote best practices in supporting deep-tech startups from innovation ecosystems of varying maturity, addressing critical barriers, including:-Lack of specialized support for deep-tech companies at national and regional levels.-Limited access to investors, peer networks, and potential clients in less developed innovation ecosystems.-Fragmented policy approaches that hinder scaling efforts across Europe.The conference will provide a structured dialogue between technology transfer offices, academia, investors, policymakers, and industry leaders to shape a cohesive deep-tech support framework. Key deliverables will include:-Best practice case studies showcasing successful models of collaboration.-Strategic insights for integrating deep-tech support mechanisms into national and EU-level programs.-A comprehens
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Development of concrete composite material and application process to construct hulls and decks of boats and other engineering shell'.

assistant: **Objectives**

Proposal prepared with the help of an Exploratory Award which included a Research Feasibility study. The Feasibility Study Report is annexed to this Stage 2 Proposal. Kaylite Technology is a new technology for building large scale artefacts such as architectural and civil engineering structures using a newly designed group of ceramic composite materials. It was originally conceived to produce high performance shell structures for use in the hulls of marine craft but the Feasibility Study demonstrated a much wider commercial potential in other, often less demanding, applications. The concept of Kaylite Technology is that complex artefacts can be designed and built by CAD/CAM on a commercial scale more quickly, accurately and cheaply than any other process currently in existence. The process enables sophisticated stress analysis to be performed at the CAD stage which can be incorporated not only into the structural design but into the physical and chemical formulation of the composite materials at the point of manufacture in a structure. The heart of the Kaylite system is a particle projector (roughly analogous to a bubble jet printer) producing very small packets of precisely batched materials which can be placed to an accuracy of +/ 0.3mm onto the structure under manufacture. Unlike conventional sandwich materials there are no shear planes between materials of differing composition; the formulation is phased gradually to produce a (pseudo homogenous) pseud sandwich structure. The theory of structural design using composites is currently unrefined and is preceded by practice; Kaylite technology is able to improve upon practical techniques and, additionally (and very importantly), to provide a powerful analytical tool for research enabling exceptionally detailed analysis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Development of an advanced design and production process of High Temperature Ni-based Alloy Forgings' in the context of a Seventh Framework call.

assistant: **Objectives**

The strong need for higher efficiency, reduced CO2, NOX emissions, weight and noise reduction in aircraft engines leads to a demand of innovative materials with optimized mechanical and physical properties. The special design of new generation geared turbofan aircraft engines with their faster rotating LPT leads to higher temperatures in the turbine, casing and engine mount and thus requires parts with increased high temperature properties. High temperature strength means in most cases bad forgeability and weldability as well as combined with high toughness challenging machinability. Thus, beside of new designs the production processes have to be altered to get high quality parts.The overall goal of this project is an improved understanding of thermomechanical processing and its effect on residual stresses and distortion as well as microstructure and mechanical properties of forgings used for improved temperature exhaust cases.The proposed project consortium has significant experience with regard to nickel base superalloys with higher temperature capability than Inconel718 like Udimet720, Waspaloy, Allvac718Plus, RENE65 and Haynes282. Together with the know-how on residual stress simulation and measurement established in several projects since 2001 a successful realization of this project is possible.Beside project management according IPMA standards six further work packages have been defined. One for radial forging and one for closed die forging will be used to optimise thermomechanical processes based on simulation and to produce demonstrator parts. Open die forgings are used for residual stress and microstructure investigations.  Material data for finite element simulation and residual stress modelling will be generated in on work package and verified together with
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Fitting The World to Minds: Brain Basis of Sharing and Transmitting Representations of the Social World'.

assistant: **Innovation**

Understanding other peoples’ minds is one of the most fundamental human skills but also the most demanding challenge our brains pose every day: To understand each other, we need to share neural representations of the external world across brains. Studying how social information is represented similarly across individual brains and how it flows from brain to brain poses huge conceptual and technical challenges for neuroscientists, who have consequently resorted to experiments using simplistic and impoverished social stimuli. However, recent advances in brain signal analysis enable us to study the brain basis of social interaction under naturalistic settings with unparalleled accuracy. This neuroimaging project aims to bridge the gap between social psychology and cognitive neuroscience by building a comprehensive neurocognitive model of how individuals maintain and communicate shared neural representations of the dynamic social world. The framework relies on testing the assumption that similarities in sensory and higher-order processing across individuals can be quantified by measuring temporal synchronization of their brain activity. We use novel signal analysis methods, experimental techniques and rapid magnetic resonance image acquisition for testing i) whether selective synchronization of brain circuits during social interaction supports interpersonal understanding, ii) whether similarities in cognitive task sets across individuals are associated with increasingly synchronous brain activity, and iii) whether intense emotional experiences enhance synchronization of brain responses and flow of information from brain to brain. The results will significantly improve our understanding of the brain dynamics of social interaction, and the proposed naturalistic neuroscience a