RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Integration of Bio-Conversion and Separation Technology for the production and application of platform chemicals from 2nd generation biomass' to be submitted under Seventh Framework.

assistant: **Abstract**

BioConSepT aims to demonstrate the technically feasibility of White Biotech processes for  the conversion of 2nd generation biomass into platform chemicals, which are 30% cheaper and 30% more sustainable than existing chemical routes or 1st generation processes. BioConSepT uses lignocellulose and non-edible oils & fats as cheap, abundantly available feedstocks, which cannot be used as food. The main achievements expected for BioConSepT are: (1) to develop the robust enzymes and micro-organisms suited for the more dirty 2nd generation feedstocks; (2) to reduce equipment costs and the number of process steps by the integration of bioconversion and highly selective separation technologies; (3) to facilitate easy integration in existing production chains by deploying combinations of bio- and chemical conversions and by proving the suitability of the produced platform chemicals for bio-based polymers, resins, plasticizers, solvents and surfactants and (4) by realisation of the 1st demonstration of integrated production chains from 2nd generation feedstocks to platform chemicals at industrially relevant scale. BioConSepT will bring novel technologies from lab to pilot scale by high level applied research. The consortium consists of 15 SMEs (suppliers of equipment, bioconversions, separation technologies and services), 10 large industrial parties (producers, end-users, engineering and consultancy companies) and 5 leading RTOs from 11 different countries. The large industrial parties and SMEs expect new products, processes, services and customers with a potential value of hundreds of M€. BioConSepT will reduce the total processing costs and thus improve the competitiveness of the European agro/food and chemical industries. The use of renewable biomass will lead to a significant
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Proteostasis of aging and stem cells' (2007-2013) targeting Seventh Framework.

assistant: **Abstract**

While it is has long been noted that genome stability is a central function required for survival of stem cells, the role of protein homeostasis (proteostasis) has not been explored. With the asymmetric divisions invoked by stem cells, the passage of damaged proteins to daughter cells can destroy the resulting lineage of cells and possibly accelerate the aging process. Furthermore, the possible retention of damaged proteins by the stem cell can result in diminished stem cell function and possibly premature aging. Therefore, a firm understanding of how stem cells maintain their proteostasis is of central importance. Because experiments with mammalian embryonic stem cells have clearly demonstrated their capacity to replicate continuously in the absence of senescence, we hypothesize that these cells could provide a novel paradigm to study the regulation of proteostasis and its demise in aging. We have recently described that human embryonic stem cells (hESCs) exhibit high proteasome activity compared to their differentiated counterparts. This enhanced proteasome activity is necessary for hESC function. Furthermore, we have uncovered that PSMD11/rpn-6, a key proteasomal subunit, is required for this activity and its mode of regulation and conservation in the aging process of the invertebrate C. elegans. Moreover, ectopic expression of rpn-6 protects from the symptoms associated to Huntington’s disease. We hypothesize that, in addition to its regulation of the proteasome, hESCs must differentially regulate multiple subcellular stress response pathways designed to protect the hESC from disequilibrium in the synthesis, folding, and degradation of its proteome. In this work, we will: 1) define the mechanisms by which enhanced proteasome activity controls hESC function; and 2) d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'MYC Network Proteins in Tumorgenesis', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Objectives?To identify and characterize new members of the Myc Network of Proteins.?To develop new model systems to assess the biological potency of the Myc network of proteins.?To identify upstream regulatory pathways and downstream effector pathways of Myc.?To identify molecular mechanisms of oncogene co-operation.Brief descriptionProteins of the Myc network are central regulators of mammalian cell proliferation and apoptosis; deregulation of their function contributes to tumorigenesis.The aim of this partnership is to characterize the biological potency of new proteins that interact with Myc. Second, the partnership aims to develop tumor-related model systems that allow a precise assessment of the biological potency of proteins of the Myc network.The major focus of the work will lie on the identification of downstream effector pathways of Myc and attempts to understand how Myc synergizes with other oncogenes to deregulate cell cycle progression and contributes to tumorigenesis.Keywords:Myc, Max, Mad, Mxi, Rox, Mnt, cell cycle, Apoptosis, Tumorigenesis, cyclindependent kinases, Neuroblastoma, breast cancer.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Rational design of hydrophobic MOFs for energy applications' (HydroMOF) targeting Horizon Europe.

assistant: **Abstract**

Metal Organic Frameworks (MOFs) represent a class of nanoporous materials that is propelling groundbreaking innovation in fields that include catalysis, gas capture and storage. The success of MOFs hinges on the possibility to tailor, based on technological demand, the properties of their cavities, with a versatility that results from the combinatorial variety of their modular, molecularly-precise structures. Recently hydrophobic MOFs are becoming increasingly popular in energy devices that exploit pressure cycles to force water to intrude and extrude the material’s cavities. Different MOFs display different Intrusion/Extrusion (IE) behaviors enabling a variety of applications that range from mechanical energy storage to vibration damping and impact absorption. IE of liquids, unlike gas adsorption, is a complex phenomenon associated to the cavity-by-cavity motion of a liquid front determined by the metastability of wet and dry cavities, a datum that is only accessible via expensive molecular simulations. This vast complexity has so far prevented a first-principle design of IE materials, with only a handful of MOFs currently being exploited for IE. Addressing these challenges HydroMOF sets to enable the rational design of IE MOFs. This is achieved first via the creation of WetNet, a physically-informed machine learning model able to predict the stability of water inside the cavities of database MOFs. Circumventing the need for case-by-case free energy simulations WetNet enables the screening of thousands of MOFs yielding designs tailored around specific applications. At a later stage molecular insight will inform original lattice models able to simulate actual IE cycles through realistic MOF cavity networks, unprecedentedly encompassing non-equilibrium, finite-size and d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Extracting funding statements from full text research articles in the life sciences'.

assistant: **Objectives**

In support of the ERC open access strategy, it is critical for the ERC to identify published scientific articles that have been based on its funding schemes, in order to assess the impact of the research supported. Currently, the relationship between funding source and article is made only sporadically, years later in end-of-grant reports, or lost altogether, as there is no structured method for recording these associations. Ideally, the funding source should be identified as part of journal manuscript submission processes, however, this idea is currently in its very early stages and will not address the backlog of articles already published. Therefore, we propose to use text-mining methods to identify funding statements in full text articles available in Europe PubMed Central as an accurate and cost-effective solution to linking articles to funding sources. We will assess the outcomes through standard text-mining quality-assessment methods as well as through consultation with ERCEA staff. Anticipating useful outcomes, we will use the methods developed to identify ERC-funded articles in Europe PubMed Central on a routine basis, and make those results available in the search and article browse features on the Europe PubMed Central website. Finally, we will explore the feasibility of extending the approach to other Europe PubMed Central funders.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Development of production unit for innovative patented cardboard packaging' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Nowadays, in Europe millions of plastic packaging trays are used and exposed of daily. Proposers have developed a new tray, which is made of cardboard and can be recycled and is suitable as organic waste. This product is patented. The goal of this project is to develop a production machine for this innovative product. In the development of the box it was taken into account that the eventual production unit has to be able to produce large numbers of these boxes in a short time. One of the main advantages of this production unit is that the production speed will be at least 4 times higher than with the present production methods and that the product can be imprinted online, if desired in full colour. The ink for printing will be water based and approved by the Food Industry. The production unit will be able to produce a whole range of different sizes of boxes. Currently, the cardboard boxes are higher in price than the plastic ones. In optimising the production method the boxes are going to have a much lower price level than initially. Moreover, with no waste disposal fee (as is often the case with plastic trays) prices are expected to become even lower than those of plastic boxes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'TOtal life cycle web-integRatEd contROl'.

assistant: **Innovation**

Current automation technology moves from centralized to distributed architectures, however there are no tools or architectures, which foresee the seamless distribution of control applications on different devices such as sensors or drives. The TORERO project creates a total life cycle web-integrated control design architecture and methodology for distributed control systems in factory automation. The main focus lies on the development of a self-configuring, self-maintaining and automatically distributed control system. TORERO will result in effort reduction and flexibility increase during the entire life cycle of a control system. In TORERO the existing device focused control system design architecture will be replaced by an application focused control system design architecture based on stringent encapsulation of device hardware and device functions and the integration of vendor provided control code modules for device access. In addition the paradigm shift to high-level language control programming is enforced. Within all parts of control design and maintenance the internet will be the main medium for information transfer.Objectives:TORERO aims at creating a total life cycle web-integrated control design architecture and methodology for distributed control systems in factory automation. The main focus lies on the development of a self-configuring, self-maintaining and automatically distributed control system. TORERO will provide the necessary means to fully exploit distributed control systems by incorporating different, distributed, non control platforms such as sensors or drives into the design process of control applications for the first time. This will allow for building a control application based on only sensors and actuators, without using a PLC (programmable l
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Integral and Algebraic Points on Varieties, Diophantine Problems on Number Fields and Function Fields', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Diophantine problems have always been a central topic in Number Theory, and have shown deep links with other basic mathematical topics, like Algebraic and Complex Geometry. Our research plan focuses on some issues in this realm, which are strictly interrelated. In the last years the PI and collaborators obtained several results on integral and algebraic points on varieties, which have inspired much subsequent research by others, and which we plan to develop further. In particular:We plan a further study of integral points on varieties, and applications to Algebraic Dynamics, a possibility which has emerged recently.We plan to study further the so-called `Unlikely intersections'. This theme contains celebrated issues like the Manin-Mumford conjecture. After work of the PI with Bombieri and Masser in the last 10 years, it has been the object of much recent work and also of new conjectures by R. Pink and B. Zilber. Here a new method has recently emerged in work of the PI with Masser and Pila, which also leads (as shown by Pila) to signi_cant new cases of the Andr_e-Oort conjecture. We intend to pursue in this kind of investigation, exploring further the range of the methods.Finally, we plan further study of topics of Diophantine Approximation and Hilbert Irreducibility, connected with the above ones in the contents and in the methodology.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Bridging the gap between Gas Emissions and geophysical observations at active volcanoes' (BRIDGE).

assistant: **Concept**

In spite of their significance in a variety of volcanological aspects, gas observations at volcanoes have lagged behind geophysical studies for a long time. This has primarily reflected the inherent technical limitations met by gas geochemists in capturing volcanic gas properties (chemistry and flux) at high-rate (1 Hz), and using permanent instrumental arrays. The poor temporal resolution of volcanic gas observations has, in addition, precluded the real-time analysis of fast-occurring volcanic processes, as those occurring shortly prior to eruptions, therefore generally limiting the use of gas geochemistry in volcanic hazard assessment. However, the recent progresses made by modern multi-component/high frequency measurement techniques now open the way for decisive step ahead in the current state-of-the-art to be finally attempted.The BRIDGE research proposal has the ambitious goals to bridge the existing technological gap between geochemical and geophysical observations at volcanoes. This will be achieved by designing, setting up, and deploying in the field, innovative instruments for 1 Hz observations of volcanic SO2 and CO2 fluxes. From this, the co-acquired volcanic gas and geophysical information will be then combined within a single interpretative framework, therefore contributing to fill our current gap of knowledge on fast (timescales of seconds/minutes) degassing processes, and to deeper exploration of the role played by gas exsolution from (and migration through) silicate liquids as effective source mechanism of the physical signals (e.g., LP and VLP seismicity, and tremor) measured at volcanoes. Finally, this combined volcanic gas-geophysical approach will be used to yield improved modelling/understanding of a variety of volcanic features, including modes/rat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'High density Interconnection for Space, Avionics and enterprise Mobility Applications' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The aim of this proposal is to provide to a new set of users (satellite systems, avionics systems and business mobility wireless services) the access to the High density Interconnection Printed Circuit Board technology. The consortium Users are mainly involved in low or medium volumes for high performances and high reliability applications. Associated with a well-experienced HDI PCB supplier, in order to guarantee a successful access, they wish to try this high volume technology in their applications. The objective of this proposal is to try this HDI technology as such or with a fine tuning, in the context of more severe environmental and functional requirements within a program described below.- Transfer of the HDI design methodology from the supplier to the Users partners.- Design of the tests vehicles PCBs manufacturing and components assembly.Objectives:The derived objectives are first to implement the HDI technology in a PCB test vehicle derived from reference boards. Then, validate that the HDI technology is compatible regarding the actual environmental requirement for space, avionics and professional wireless applications: at material level, process level and reliability level. Demonstrate that the use of the HDI technology lead to improve the electrical performances of the applications (especially EMI and CEM performances using embedded metallic shielding) and demonstrate that the use of this technology lead to enhance the system integration and reduce the weight size and layers count.Work description:For the users, this program aims at the introduction of HDI PCB technology for the design of new products. For this purpose, the technical approach for this trial program will be as follow.The first step is dedicated to the selection of the HDI technology and the d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on '3D and Speech Interfacing Technologies'.

assistant: **Innovation**

INTERACT will use all three senses: vision, speech and touch, with the aim to overcome existing limitations in the way information is presented and interacted with in the new generation of computer platforms. The emphasis will be placed on 3D information visualization and manipulation based on the fusion of three core technologies: Holographic Displays, Computer Vision based 3D Hands Tracker and Natural Speech Processing. The Holographic Displays will provide, highly realistic, naked eyed, representations of 3D information to multiple simultaneous users, each viewing a different perspective. 3D objects may appear floating behind or in front of the display and users will be able to walk around the screen in a wide field of view seeing objects and shadows moving continuously as in the normal perspective without causing strain to the user. The Hands Tracker will use advanced computer vision techniques to achieve accurate detection of the movements of the hands and fingers of the user in the 3D space with the aim of precise manipulation of virtual objects and advanced gesture interpretation. Finally, the Speech Interface will allow intelligent dialogue exchange with the machine using plain words.The project will produce an advanced information access point where the three mentioned interfacing technologies will be fully integrated for unprecedented levels of realism and interactivity. Within the system virtual representations will be displayed realistically in true 3D and the user will be able to shape or manipulate the virtual objects in real time using his own hands, while he issues gesture commands or dialogues with the context aware natural speech interface for more complex interaction requests with the machine. The new technology will be aimed at either home or profess