RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Is there a limit to yield?'.

assistant: **Innovation**

Plant breeders are challenged with sustaining global crop improvements. Is there a limit to crop yield? This project will address this central question using processing tomatoes as a model for a mechanized crop. By integrating in a single web-based platform of ‘Phenom Networks’ a broad germplasm base, deep phenotypes, and multiple genome sequences of tomato species, we will identify the genes and mechanisms that dictate crop productivity and implement them in the creation of next generation F1 hybrids. Our work is founded on our years of efforts to establish the following integrated genetic pillars: 1) The tomato genome revealed SNPs for broader marker-assisted selection between cultivated parents and untapped diversity from closely-related red-fruited ancestors. We will develop new elite parental lines into which all discovered traits will be introduced. 2) We will enrich the narrow genetic base of modern processing tomato by pyramiding recessive, additive, dominant and overdominant QTL from six wild species introgression lines (ILs) and field-test them in diverse environments. 3) By producing hybrids with ‘recessive’ deleterious mutants we have identified heterosis genes that increase yield by ~50%; these will be combined with the IL QTL. 4) Finally, we will focus on newly discovered “stability QTL” that significantly improve the reproducibility of yield effects by canalizing this phenotype in spite of environmental perturbations. This multi-faceted integrated tomato breeding effort will unite classical and genomics assisted methods with statistical genetics to demonstrate that yield barriers of the leading commercial hybrids are only there to be broken. We will clone the genes responsible for yield, domestication, heterosis, epistasis and canalization and explore the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Modular avionics for light aircraft'.

assistant: **Innovation**

The scientific and technical objectives of this research proposal concern the definition of a modular avionics system including ergonomic instrument panels displays for light single engine aircraft, light twins and gliders. Research is required to define an efficient, flexible, open and reliable communication architecture between avionics and instrument panel control and display functions. The research addresses ergonomics of the plane operations. Breadboarding, integration and tests in a light aircraft will be performed.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Engineered nanocarriers for simultaneous anticancer immune response and “switching” of tumor-associated macrophages for intranasal glioblastoma treatment' (BraINstorm), addressing dissemination and exploitation.

assistant: **Impact**

Glioblastoma (GBM) remains a non-curable disease due to its high complexity and its position beyond the blood-brain barrier, which precludes access by conventional therapies. The current standard of care includes tumor resection surgery followed by radiotherapy or chemotherapy; an invasive process with a survival rate after five years is less than 5%. Tumor-associated macrophages (TAM) type 2 (M2 macrophages) comprise 30-50% of the infiltrated cells in GBM microenvironment and support tumor expansion. Immunotherapy represents an appealing strategy to treat several cancer types by turning the immune system against tumor cells; tumor antigen peptides (TAAs) recently emerged as an immunotherapeutic approach that can provide for a long-lasting immune response. Immunomodulatory oligonucleotides can “switch” M2 macrophages into M1 macrophages that produce an anti-tumoral effect. The BraINstorm (Brain INtranasal storm) project aims to engineer a hyaluronic acid (HA)-based combination conjugates that tackle GBM by the stimulation of the immune system via the delivery of TAAs and an immunomodulatory oligonucleotide (CpG) that promotes M2 macrophage “re-education” generating an “anticancer storm”. In parallel, taking advantage of the intrinsic muco-adhesivity of HA, BraINstorm will explore the nose-to-brain drug delivery, a more patient-friendly route that reduces the invasiveness. Novel combination immunoconjugates will be fully chemical-physical characterized and preliminary in vitro studies will be performed assessing the biocompatibility, drug release, and nasal mucosa barrier crossing in an ex-vivo model. Finally, the prophylactic and therapeutic activity of the HA-based conjugates will be in vivo explored in a clinically relevant GBM in vivo model through intranasal (IN) an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Going Deep and Blind with Internal Statistics' (DeepInternal) targeting Horizon 2020.

assistant: **Abstract**

Unsupervised visual inference can often be performed by exploiting the internal redundancy inside a single visual datum (an image or a video). The strong repetition of patches inside a single image/video provides a powerful data-specific prior for solving a variety of vision tasks in a “blind” manner: (i) Blind in the sense that sophisticated unsupervised inferences can be made with no prior examples or training; (ii) Blind in the sense that complex ill-posed Inverse-Problems can be solved, even when the forward degradation is unknown.While the above fully unsupervised approach achieved impressive results, it relies on internal data alone, hence cannot enjoy the “wisdom of the crowd” which Deep-Learning (DL) so wisely extracts from external collections of images, yielding state-of-the-art (SOTA) results.  Nevertheless, DL requires huge amounts of training data, which restricts its applicability. Moreover, some internal image-specific information, which is clearly visible, remains unexploited by today's DL methods. One such example is shown in Fig.1.We propose to combine the power of these two complementary approaches – unsupervised Internal Data Recurrence, with Deep Learning, to obtain the best of both worlds. If successful, this will have several important outcomes including:• A wide range of low-level & high-level inferences (image & video).• A continuum between Internal & External training – a platform to explore theoretical and practical tradeoffs between amount of available training data and optimal Internal-vs-External training.• Enable totally unsupervised DL when no training data are available.• Enable supervised DL with modest amounts of training data.• New applications, disciplines and domains, which are enabled by the unified approach.• A platform for substa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Integration of Renewable Energy Sources and Distributed Generation into the European Electricity Grid (IRED)'.

assistant: **Innovation**

Background: There are seven projects running which are supported by the European Commission under FP5 dealing with the integration of Renewable Energy Sources (RES) and Distributed Generation (DG). This cluster represents a total budget of about 35 million? More than 100 participating institutions from research, industry and the utility sector are contributing. Proposed Actions: The subject of the proposed CA is to extend the existing cluster activities in such a way that a real European added value by mobilising research will be obtained as a major contribution to the ERA. This extension will be realized by the inclusion of forthcoming projects supported by FP6 by national and regional activities.1. A systematic exchange of information by improving links to relevant research, to regulatory bodies and to policies and schemes on the European, the national, the regional and the international level.2. Set-up of strategic actions such as trans-national co-operation, the organization and a co-ordination of common initiatives on standards, testing procedures and the establishment of common education.3. Identification of the highest priority research topics in the field of integration and formation of appropriate realization schemes.a) The establishment of an expert-group covering important cross-cutting areas such as power-quality, ICT/IST, laboratory experiments est.)The formation of a group of contact persons to national, regional and international policy).Set-up of a full data- and information-exchange system with links to national, regional and international information systems)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Disrupting Logistics in Smart Cities and Regions through an Advanced Logistics Platform.'.

assistant: **Concept**

Urban logistics are growing every year, pressed by new eCommerce business, namely in the retail sector and requiring high service levels for logistics, and at the same time, public authorities strive to ensure the sustainability of urban mobility.LOOP is a disruptive new way of planning and managing last-mile logistics in smart cities, bringing Suppliers, Logistic Service Providers and Public Authorities together in the same platform, by de-coupling goods from last-mile logistic service providers. LOOP creates a multi-brand Logistic Service Provider federation based on Pick up and Drop off Delivery Points (PUDOs), Aggregation Boxes (AB) and pre-determined urban ring circuits that can be dynamically changed in real-time to address logistic requests on the fly and physical or regulatory constraints (traffic, municipal restrictions, etc.).Our objective is to demonstrate LOOP in European smart cities, and prove that this is a new, disruptive way to reduce operation costs for logistic operators, while increasing service level for Suppliers and Shoppers, while respecting municipal regulations. By paying a small transaction fee per delivery, Logistic Service Providers can tap in a federated client pool based on their fleet availability and location.We estimate that in 2020 this new market will be worth 250M € in Europe alone, and our clients are they logistic operators, that will pay a fee per delivery/pick-up service. By being a multi-brand platform, LOOP allows local SMEs to be part of the last-mile logistics, mitigating risks (large client base from LOOP) and increasing their fleet in a commercially sustainable way (no need for critical mass fleet size).Logistema has developed LOOP as the results of over 20 years of consultancy experience on logistics for public and private
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Lc2003' to be submitted under Fifth Framework.

assistant: **Abstract**

Logic Colloquium 2003 is the most important event in the area of logic in the world in 2003. It is the European Summer Meeting of the Association for Symbolic Logic, the international head organization of logicians, and these meetings have become the main annual conference of top logicians, young researchers and students from all over the world. The event has tutorials aimed at students, contributed papers- and poster sessions for young researchers, high level plenary lectures and special sessions reporting on new cutting-edge research in logic.The goal is to advance mathematical logic as a multi-disciplinary branch of mathematics, philosophy, computer science and linguistics with outstanding importance for the present day society marked by information technology. The impact of logic ranges at present from theoretical mathematical study, with mainly foundational importance, to sophisticated applications in computer science, philosophy and linguistics.In all the main areas of mathematical logic there will be keynote speakers reporting on cutting-edge new results for the wider audience of logicians and specialists alike. There will be also special sessions highlighting the most recent innovations of each area. The most dynamic topics at the moment are:l) Set theory: potential cofinality theory (speaker: Saharon Shelah, Jerusalem) and descriptive set theory (Matthew Foreman, Irvine). 2) Model theory: stability theory (Boris Zilber, Oxford) and finite model theory, with close links to computer science (Martin Grohe, Edinburgh). 3) Recursion theory: degrees of unsolvability (Leo Harrington, Berkeley) and effective model theory with relevance to computer science (Richard Shore, Cornell). 4) Proof theory; reductive proof theory and the higher infinity (Michael Rathjen, Leeds).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Bringing Human Neuromotor Intelligence to Robots' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The H2R project will bring a solid theoretical understanding of human neuromotor control, and develop novel control methods for robots interacting with environments and with humans, based on  human control strategies for interactions. The biomimetic motor behaviour for robots will perform better than the existing robotic controllers, and closer to human performance in terms of compliant interaction with the environment and adaptation to its dynamic characteristics, intrinsic safety and reliability, and energy efficiency. This novel controller will be implemented and demonstrated on rehabilitation and cooperative robots, in collaboration with European partners. This project may deeply impact applications where successful task completion requires people and robots to collaborate directly in a shared workspace.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Intramer-mediated multi-parallel mapping of signalling pathways' (IntraMAP).

assistant: **Innovation**

Cellular behaviour is methodically studied using systems biology approaches that analyse the presence, absence, or oscillation of biomolecules. To this end, exogenous perturbations, among others, are used to alter protein expression and study their effects on cellular homeostasis. However, proteomes are inherently versatile and diversified by alternative splicing, protein cleavage, and post-translational modifications (PTM). Similarly, the spatiotemporal formation of multicomponent complexes plays an important but less well understood role in cellular homoeostasis and disorders. Specific recognition of these complexes by ligands is a difficult task to solve. Therefore, deciphering signalling cascades at the proteome and complex levels requires technologies that enable the identification of protein-binding and -inhibiting compounds that are sensitive or tolerant to PTMs and can recognize protein complexes. Intracellularly expressed aptamers, known as intramers, offer a solution to this challenge. The IntraMAP project will develop generally applicable paradigms for the automated evolution of intramers and combine them with cellular screening methods. In this way, intramers will be identified that are optimally adapted to cellular environments and effectively disrupt signalling cascades. These intramers will be used to identify signalling components and protein complexes associated with these cascades. They will be applied to various cells, organoids and in vivo to uncover fundamental principles of complex signalling events. The project has a strong interdisciplinary focus and will open novel avenues for the analysis of biomolecules. It has implications ranging from life sciences to systems biology, and will not only establish intramers as a broadly applicable discovery te
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'ECO2Clouds: Experimental Awareness of CO2 in Federated Cloud Sourcing' under Seventh Framework.

assistant: **Concept**

Ecological implications of the rapid proliferation of cloud-based IT infrastructures form an important gap in the current state of the art in both research and practice. Addressing this gap is vital for sustainable future developments in cloud computing. ECO2Clouds will investigate strategies that can ensure not only effective application deployment on the cloud infrastructure but also reduce the resultant energy consumption and CO2 emissions.The need for novel deployment strategies becomes more evident when an application spans multiple clouds. Cloud providers operate under different regulatory frameworks and cost structures in relation to environmental policies and energy value-chains. In addition,  optimising the way key assets such as application logic and databases are deployed is constrained by a set of non-functional requirements such as quality, privacy and cross-platform, service-level agreements.To date, little is known about how to incorporate carbon emissions and energy consumption into application development and deployment decision models. ECO2Clouds will provide a timely, challenging and highly innovative approach to cloud computing service delivery, which will tackle the following issues:-Develop cloud application programming interface extensions and mechanisms to collect eco-metrics at infrastructure and VM level, and quantify the environmental impact of execution at infrastructure and application level-Investigate the key environment, quality and cost parameters needed so as to underpin a holistic approach to multi-cloud application deployment-Develop evaluation mechanisms and optimization algorithms to assess different parameter configurations and their influence in energy-efficient cloud sourcing and application-deployment strategies-Integrate the ca
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'High performance multi-fuel Cfb with advanced steam cycle' (1998-2002).

assistant: **Concept**

The major object of the proposed work is to achieve a breakthrough in utility solid fuel power generation by high efficiency Circulating Fluidised Bed (CFB) technology with supercritical (SC) steam parameters. An essential basis in reaching the goal is to adapt and develop existing and new innovations and advancements in CFB boiler technology.These innovations are the necessary premise when integrating and optimizing once through OT sliding pressure steam cycle and large scale CFB boiler. Development of OTSC steam cycle for CFB technology will raise the efficiency up to 43-45% depending on the condenser conditions and thus, it will increase power production efficiency by 10 to 15% in CFB's. Use of renewables together with other fuels and the high power production efficiency with OTSC CFB will make it possible to decrease CO2 as well as other emissions by 15 to 25% compared to conventional technologies.