RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The first lubrication- and coating-free stoppers for Prefillable Syringes' (LUBRIGONE), addressing dissemination and exploitation.

assistant: **Impact**

With a global value of €4,663 million in 2017, Prefillable syringes (PFS) for administration of medical injections have seen an increased use in recent years, thanks to their advantages over the combined use of empty syringes and vials, such as their ease of use, accurate dosage (with less overfill), improved safety and reduced risk of contamination However, PFS require lubrication (usually liquid or baked-on silicone) to ensure their functionality, and this lubrication (which is in direct contact with the medical dosage in the PFS throughout its entire shelf life) may affect the pharmaceutical compounds, reducing their efficacy and causing health and safety issues for patients. To solve this problem, we developed LUBRIGONE, a new line of PFS stoppers combining a chemically inert Thermoplastic Elastomer (TPE) and unique sealing profile designs, which eliminates the need for lubrication and/or coating of the stopper and container. In this way, LUBRIGONE enables a completely clean injection system, protecting sensitive injectables from pollution, and protecting users against potential damage, while granting an optimal functionality (maintaining an acceptable break loose force and mean forces in PFS). Our company, Injecto A/S was founded in 2014 with the goal to develop safe medical devices with primary focus on safe PFS syringes and their stoppers, to create safe and long-term stable drug injections. As a result, the LUBRIGONE project, will be a cornerstone for us, as it will enable us to exploit the market opportunity derived from its competitive advantages over current silicone-oil coated rubber stoppers, and the lack of feasible cost-effective alternatives, In this way, it will facilitate our growth and international expansion: our forecasts are to sell 21.4 million un
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Innovative cost-effective hybrid system based on integration of a MCFC and a gas turbine for high efficiency dispersed CHP generation' (MOCAMI).

assistant: **Concept**

This European project aims at developing and demonstrating a small-sized hybrid system with the combination of the MCFC technology and of micro gas turbine (MTG). The development of such a small-sized hybrid system will allow lowering the production costs through the development of new and simpler processes with a better quality control and a higher yield for the different components.This hybrid system will be suitable for the development of a dispersed generation system, suitable for CHP supply at high electrical efficiency and very favourable environmental impact. The technology chosen should enable to provide effective solutions in the 100-500kW range, corresponding to a very wide potential market (residential, agricultural, small industries); as a matter of fact, the approach should facilitate the end users and the Energy Services Companies to adopt this solution.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'EStages.UK. Spanish theatre in United Kingdom (1982-2019)' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

“EStages.UK. Spanish theatre in United Kingdom (1982-2019)” rehearses a new approach to the study of theatrical exchange in Europe, pioneering collaboration between scholars and theatre practitioners whilst promoting gender equality. The project pursues three interrelated strands, focusing respectively on research, practice and pedagogy. First, it will provide a history of Spanish plays performed in the UK since the consolidation of democracy in Spain, drawing a map of the circuits through which they have moved. Second, it will foster new strategies for collaboration between academia and practitioners, through close collaboration with the first UK-based company dedicated to the staging of Spanish-language theatre: the Spanish Theatre Company (STC). Third, it will develop new materials to promote the study of Spanish theatre in secondary and tertiary-level education. In order to achieve these three objectives, the project includes a two year training plan at the University of Leeds, and two short visits at the Royal Central School of Speech and Drama. I will act as a conduit for knowledge exchange between these two leading centres for Theatre Studies, with established track records in research excellence, and the STC as well as other professional stakeholders. A paramount concern is to provide a forum for networking opportunities and dialogue between academia, practitioners, and cultural managers thereby reformulating and enhancing theatrical exchange and cultural understanding across borders and between different European nations
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Biomarkers relevant to oil and gas industrial activties in low temperature marine ecosystems' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

Research objectives and content The main objective will be, from an ecotoxicological point of view, to develop some biomarkers that will be relevant to oil and gas industrial activities with some cold marine species. The following questions are adressed in the proposed thesis: 1) How does low temperature influence the uptake and effect of key components of oil, notably polyaromatic hydrocarbons (PAHs) ? 2) Are the responses of well-established biomarkers (the neutral red lysosomal assay, multi-xenobiotic resistance responses, cardiac activity and scope for growth) to PAH exposure in selected crustaceans and molluscs affected when organisms are held at low temperatures ? 3) Does exposure to PAH influence the ability of organisms to produce molecular responses to low temperatures? 4) Do organisms acclimated to low temperatures (i.e. those living normally at low temperatures) exhibit differences in tolerance to PAHs compared to organisms which normally live at higher temperature? 5) Can biomarkers be used to monitor the impact of PAHs associated with discharges by the oil industry Training content (objective, benefit and expected impact) The objective is to carry out this research as a PhD Thesis in order to get specialised in ecotoxicology in low temperature marine environment and provide some scientific data concerning the potential impact of oil and gas industries activities on the fauna of these cold region. Links with industry / industrial relevance (22) The newest frontier areas for oil and gas Exploration and Production in Europe are characterized by cold waters: -either in the arctic environment of the Barents sea, where low temperatures are associated with seasonal sunlight activity -or in the deep waters of the North Western European Atlantic margins where low te
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The Multisensory Brain in a Social World: When, Where, and How Do Multisensory and Social Processes Interact in the Brain?' under Horizon Europe.

assistant: **Concept**

Sensory experiences are a vital aspect of human existence. In everyday life, our senses are flooded with input, constantly picking up multiple unisensory signals at once. In our brain, these incoming signals are either processed separately or integrated into one unitary percept  a process known as ""multisensory integration"". Intriguingly, this integration process can be affected by the social context people find themselves in, for example such that people perceive certain perceptual illusions more intensely when experiencing them jointly with another person. To date, this effect has been observed on a behavioral level yet it is not clear what happens in the human brain  on a neurophysiological and computational level. Thus, in the proposed research I will investigate the interplay between multisensory and social processes from a neuroscientific perspective. I aim to (1) identify when the social context affects multisensory processing, (2) localize where in the brain the social context affects multisensory processing, and (3) model how the social context affects multisensory processing. To this end, I will conduct experimental studies, using a combination of electroencephalography (EEG) and functional magnetic resonance imaging (fMRI), complemented by a cognitive modeling approach. I will use EEG to address the temporal (when) and fMRI to address the spatial processing dimension (where). To address the third objective (how), I will fit a Bayesian causal inference model to the behavioural data. The overarching goal of my research is to extend the current view on multisensory processing by a social component, thereby contributing to a more holistic account of human perceptual processing.""


**Keywords:** Multisensory Perception,  Social Cognition, Joint Action
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Spectral Diversity within Ryugu' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

To understand the history of the chondritic asteroid Ryugu and whether it had a role in delivering volatiles and organic material to early Earth, SDR will constrain the mineral and geochemical variability of sediment samples from Ryugu on a grain and sub-grain scale. Because Ryugu is a rubble-pile asteroid made of re-accreted pieces of the parent body/bodies, near-surface sediment collected by the Hayabusa2 mission represents many depths within the interior of the parent. However, current analyses of collected reflectance spectra are done at the bulk sample scale which can average over interesting features to determine the major components. As individual grains are prepared to be sent out for proposed science, each grain is being documented from multiple viewing angles using the MicrOmega hyperspectral imager (0.99-3.65 micrometers) developed at IAS. This has created an enormous, rich dataset of ~20 hyperspectral images for each of 350 grains analyzed so far, and this dataset will continue to grow over the coming months. By conducting novel statistical analyses of this dataset of >7000 high-resolution image cubes (22 micrometers/pixel), I will identify co-occurring mineral phases, minor phases, and variation in organic phases that have implications for the aqueous alteration conditions within Ryugu and its parent body. Statistical analyses will include: principal component analysis, k-means clustering, distinctiveness measures, pixel-to-pixel correlation, edge detection, and network centrality. My experience publishing on statistical analyses of existing, noisy datasets has prepared me to extract meaningful information from this large, complicated dataset. This work will culminate in an updated model of formation and alteration on Ryugus parent body which relies on the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Defining functional networks of genetic causes for ALS and related neurodegenerative disorders' (ALS-Networks) targeting Horizon 2020.

assistant: **Abstract**

Brain and spinal cord diseases affect 38% of the European population and cost over 800 billion € annually; representing by far the largest health challenge. ALS is a prevalent neurological disease caused by motor neuron death with an invariably fatal outcome. I contributed to ALS research with the groundbreaking discovery of TDP-43 mutations, functionally characterized these mutations in the first vertebrate model and demonstrated a genetic interaction with another major ALS gene FUS. Emerging evidence indicates that four major causative factors in ALS, C9orf72, TDP-43, FUS & SQSTM1, genetically interact and could function in common cellular mechanisms. Here, I will develop zebrafish transgenic lines for all four genes, using state of the art genomic editing tools to combine simultaneous gene knockout and expression of the mutant alleles. Using these innovative disease models I will study the functional interactions amongst these four genes and their converging effect on key ALS pathogenic mechanisms: autophagy degradation, stress granule formation and RNA regulation.  These studies will permit to pinpoint the molecular cascades that underlie ALS-related neurodegeneration. We will further expand the current ALS network by proposing and validating novel genetic interactors, which will be further screened for disease-causing variants and as pathological markers in patient samples. The power of zebrafish as a vertebrate model amenable to high-content phenotype-based screens will enable discovery of bioactive compounds that are neuroprotective in multiple animal models of disease. This project will increase the fundamental understanding of the relevance of C9orf72, TDP-43, FUS and SQSTM1 by developing animal models to characterize common pathophysiological mechanisms. Furth
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Enhanced participation in IST Projects related to eHEALTH and eINCLUSION' (EPIST), addressing dissemination and exploitation.

assistant: **Impact**

The EPIST project has the objective to boost NMS and ACC participation in IST activities related to eHealth and eInclusion through the implementation of two channels: a virtual one in the form of a pilot portal to facilitate the transfer, exchange and sharing of information as well as contacts among NMS and ACC organisations operating in the field of eHealth and eInclusion and a real one in the form of brokerage events, workshops and technical assistance.Raising awareness, disseminating information and training will also play an essential role in achieving this objective. EPIST will establish direct relationships with a large number of industrial and research organisations in these countries, to promote IST opportunities and assist NMS and ACC organisations in their participation in IST projects in the areas of eHealth and eInclusion and prepare them for future participation in FP7.The main activities to be carried in this context are:- Raising the awareness of NMS and ACC organisations of the technological and market state of the art and forecasts in the field of eHealth and eInclusion- Appraisal of the capability of NMS and ACC organisations to successfully operate in this evolving market sector- Identification of the roles that organisations from NMS and ACC can play in IST projects- Identification and contact of NMS and ACC organisations operating in the sector of eHealth and eInclusion- Realisation and maintenance of an interactive database on the project web site allowing to optimise assistance given to NMS and ACC organisations- Awareness and training of NMS and ACC organisations through the organisation of national workshops- Organisation of trans-national brokerage events and other partner-search activities- Technical assistance and help desk for NMS and ACC or
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Direct filament wound rotor carbon resin sleeves by bulk curing and layer-by-layer Electron beam polymerisation' (E-SLEEVE) targeting Seventh Framework.

assistant: **Abstract**

E_SLEEVE activities deal with the design, set-up and demonstration of two distinct processes for the filament winding of the required carbon composite retaining sleeve, to be realized directly integrated onto the high speed motocompressor rotor of air conditioning systems used in aircraft application: the first one will use Cyanate Ester resin and subsequent bulk curing, the second one will use specific resins for high temperature use and for direct layer-by-layer curing to be performed via low energy Electron beam, simultaneously to the filament winding process itself. Each process will be validated by manufacturing the required five sleeves directly on the rotor sub-assembly. Next Technology Tecnotessile has internal expertise and equipment from previous projects and commissions allowing to fulfil the Topic expectations. Two European-level experts in layer-by-layer E-beam curing for aerospace applications, will be involved to advice on resin formulation and provide support to process design and set-up and to validation activities. Further industrial up-scaling scenarios with cost analysis will be produced for both processes and full collaboration with Topic Manager on exploitation and dissemination activities will be provided.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Synthesis of magnetic quantum dots' under Sixth Framework.

assistant: **Concept**

Aqueous dispersions of super-paramagnetic iron oxide nanoparticles capped with QDs with controlled size, surface chemistry and morphology will be synthesized. Development of composite nanoparticles of luminescent QDs and magnetic nanoparticles offers a tremendous opportunity to create multifunctional single entities that can be held&dragged by an external magnetic and simultaneously detectable by their luminescence/magnetics which would impact many technology areas but especially, sensor, separation and diagnostic imaging.Availability of a spectrum of colours controlled by the size of the QDs, combined with decoration of particles with molecular markers allows simultaneous analysis of multiple analytes, binding to multiple receptors, identification of multiple abnormalities, simultaneous imaging and delivery, dual imaging, detection and separation opportunities as well as modes of quantification. Synthesis of QDs (CdS/ZnS) and super-paramagnetic iron oxide nanoparticles in aqueous solutions at low temperatures from soluble salts will be optimised and capping of particles with bifunctional organic molecules to achieve controlled size, stability and affinity between the two types of particles will be investigated.Surface capping molecules will be chosen specifically for the composite formation, with surface binding thiol moieties for CdS/ZnS and trialkoxysilane or carboxylic acid functionality for iron oxide. Finally, one pot synthesis of the composite nanoparticles will be attempted the first time, to the best of our knowledge, by first preparing the iron oxide and then nucleating the QD on the particle without intermediate isolation of the magnetic nanoparticles. Methods are general enough to extent it to different QD compositions and a variety of new composite nanopart
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'A sweet solution: novel antiviral siRNAs to help rescue the sugar beet industry'.

assistant: **Innovation**

Beet Yellows Virus (BYV) is one of the most destructive pathogens, causing Virus Yellows disease that underlies up to 50% yield losses in sugar beet. The recent regulatory ban on the use of neonicotinoid pesticides in EU has worsened the damage to the EU sugar beet industry. Given the urgency of the current problem caused by BYV, we propose to take advantage of a molecular biological approach to employ small molecular inhibitors called “artificial small interfering RNAs” (art-siRNAs), and demonstrate their ability to specifically bind to and deactivate BYVs within the plants. Our proposal substantially builds on fundamental research outputs from ERC Starting Grant GA680324. We aim to design art-siRNAs that are based on in vivo RNA structure features of BYV RNAs in sugar beet plants and demonstrate high efficacy in virus cleavage or degradation. We will comprehensively assess and validate the effectiveness, efficiency and safety of our structure-based designed art-siRNAs (ultraRNAs) within the laboratories, glasshouses and in-field. We envisage that our art-siRNAs will be applied to sugar beet seed pellets and will be taken up by the seedlings as they grow. When BYV infects these treated plants, we anticipate that our art-siRNAs will bind to the BYV RNA strands and deactivate them, preventing disease. We are confident that through this Proof of Concept we will be able to demonstrate the high performance of our ultraRNAs in terms of not only achieving high efficacy of BYV degradation, but also significantly reducing the quantity of art-siRNAs needed, ideal for incorporating into the seed coating. Ultimately, through follow-on work, our ambition is to provide sugar beet growers with an environmentally-friendly, safe, reliable, efficient, sustainable and long-lasting protec