RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Management policies for priority water pollutants and their effects on foods and human health : general methodology and application to chinese river basins' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

The goal is to identify effective and sustainable policies for the management of surface and ground water pollutants, taking account of their relationships with food production and human health. Based on scientific methods for the evaluation of pollutant input and transport by water, of sanitation techniques, of the use of water for human needs, food production and industrial activities, and on the analysis of relationships between pollutants and human health, fuzzy logics, multicriteria decision and geographical protection zoning approaches will be applied to define priority policies for water pollutant management. The expected result is a comprehensive and rigorous methodology to define water pollution management policies. with a wide range of applicability, i.e. valid for many different river basins.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'In the brain, at the level of a single synapse an individual astrocyte releases several gliotransmitters' to be submitted under Seventh Framework.

assistant: **Abstract**

In the brain, information is transmitted from one neuron to a second one at the level of a specialized structure, the synapse. During a long time, the transmission of information in the brain was only a neuronal story. Indeed, it was considered that the synapse was made of only two neuronal components: a presynaptic terminal that releases neurotransmitters and a postsynaptic element that receives and integrates information. However, since the last two decades, a third protagonist, the astrocyte, has entered this story. This third partner plays crucial role as regulator. To do that, the astrocyte detects the synaptic signal, encodes activity and in turn modulates the transfer of information by releasing active substances name gliotransmitters. By releasing distinct gliotransmitters like purines, D-serine, or glutamate, the astrocyte modulates several levels of synaptic communication in the brain. However, we do not still know if an individual astrocyte releases several gliotransmitters and thus modulates several forms of synaptic communication at the level of synapses it covered. To push further the boundaries understanding of the processing of information in the brain, first, I propose to establish if an individual astrocyte releases several gliotransmitters. Then, in a second time, using state-of-the-art cellular imaging techniques during electrophysiological experiments, I will determine if at the level of a single synapse the astrocyte releases these gliotransmitters and if their respective release depends on distinct calcium dependent mechanisms. This project will have strong consequences on our current vision of the tripartite synapse. Indeed, if several gliotransmitters are released at the level of a single synapse, the third element will modulate appropriately di
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Harvesting Non-Classical Fluctuations with Thermal Machines' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The goal of this action is to contribute towards the development of thermal machines which harvest the thermal as well as quantum fluctuations that are present in nanoscopic devices. To this end, a better understanding of fluctuations in thermal machines is required. The present proposal therefore includes a thorough investigation of fluctuations in quantum thermal machines. A focus lies on the non-classical character of these fluctuations and on the extraction of work from quantum heat engines. The proposal is divided into four work packages. In order to certify non-classical behavior, the first work package develops appropriate witnesses of non-classicality. The fluctuations in thermal machines are then investigated in three complementary work packages. Work package two investigates the fluctuations of heat, work, and efficiency in heat engine models. Non-classical behavior is expected to manifest itself in these fluctuations. A novel, Keldysh type input-output formalism will be developed to go beyond the standard regime of weak coupling between machine and thermal reservoirs. Work package three focuses on fluctuations that arise due to the finite size of thermal reservoirs present in mesoscopic systems. To this end, a novel formalism based on stochastic path integrals and quantum master equations will be developed. Work package four finally focuses on the crossover from a classical to a quantum regime. To this end, thermodynamic processes such as the expansion of a gas are investigated. Explicitly taking into account how work is extracted from the system, back-action effects from the corresponding quantum measurement are investigated. Together, these work packages give a rather complete picture on different types of fluctuations in quantum thermal machines. This is e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Drive your Electric Vehicle with the Power of the sun'.

assistant: **Innovation**

Electric cars will grow at impressive rates until 2030. In this context big investments are being done in the installation of charging points. These only use power from the grid, which presents three key drawbacks: capacity expansions in the power grid operator are needed, expected increasing power prices will make driving expensive and electric mobility will not be carbon free.  Meanwhile, solar photovoltaic has seen a great evolution in the past years where the price of panels has drastically decreased. This offers an opportunity to use solar energy for direct electric vehicle charging at low energy costs. However, solar carports have not been developed at industrial scale because it remains expensive due to engineering efforts to integrate the solar modules in the carport structure, labor to assemble and install the systems and the use of heavy materials like steel to support the structure. We have created e-port, the integrated EV solar carport made as a modular system that can be installed anywhere hence eliminating engineering efforts and allowing to industrialize its production, decreasing assembly cost (by 80%). Furthermore, we offer a plug and play system that drastically reduce installation time (from 10 days down to 1), reduces energy cost by 25% and at last, it is produced with carbon fibre and aluminium instead of heavy materials such as steal. This unique material combination leads to a superior performance at lowest possible weight (45% lower vs. similar solutions).In the very dynamic market of electric vehicles (CAGR2018-2025 of 43.8%) that will reach €40 billion in 2025, we aim to create a very profitable project.  With a total investment of €1.89 million, we expect to generate a R.O.I.2026 of 3.98, achieving payback in <3 years. We will achieve that by
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'How do we keep apart internally generated mental images from externally induced percepts? Dissociating mental imagery, working memory and conscious perception.' (BRAINIMAGES) targeting Seventh Framework.

assistant: **Abstract**

Conscious experiences normally result from the flow of external input into our sensory systems. However, our minds are also able to create conscious percepts in the absence of any sensory stimulation; these internally generated percepts are referred to as mental images, and they have many similarities with real visual percepts; consequently, mental imagery is often referred to as “seeing in the mind’s eye”. Mental imagery is also believed to be closely related to working memory, a mechanism which can maintain “offline” representations of visual stimuli no longer in the observer’s view, as both involve internal representations of previously seen visual attributes. Indeed, visual imagery is often thought of as a conscious window into the content of memory representations. Imagery, working memory, and conscious perception are thus thought to rely on very similar mechanisms. However, in everyday life we are generally able to keep apart the constructs of our imagination from real physical events; this begs the question of how the brain distinguishes internal mental images from externally induced visual percepts. To answer this question, the proposed work aims to isolate the cortical mechanisms associated uniquely with WM and imagery independently of each other and independently of the influence of external conscious percepts. Furthermore, by the use of neuroimaging and brain stimulation, we aim to determine the cortical mechanisms which keep apart internally generated and externally induced percepts, in both health and disease. This is a question of great clinical interest, as the ability to distinguish the perceived from the imagined is impoverished in psychotic disorders. In addition to revealing the mechanisms underlying this confusion, the present project aims to allevia
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Hydrogen For All of Europe (HY4ALL)'.

assistant: **Innovation**

Despite major technological development and the start of commercial deployments of the fuel cells and hydrogen technology, the public awareness of FCH technologies has lagged behind this technical progress so far, restricting the appetite of potential customers and risking a lack of support from policymakers. To address this challenge, a consortium of leading experts has come together, combining communication experts, PR of established manufacturers and technology suppliers and world-class experts on the societal benefits of low carbon technologies. Together, the they will deliver HY4ALL, an ambitious programme to drive a step-change in awareness and excitement around fuel cells and hydrogen and deliver clear and consistent messages that resonate with all audiences, from policymakers to the general public. The project will be active in minimum 11 member states, and will be closely linked to the large numbers of existing hydrogen initiatives and demonstrations, maximising its impact and allowing the communication strategy to influence dissemination work beyond the project for lasting effects.The project aims will be delivered through the following activities:• Development of an overarching communication strategy, that will form the basis for all subsequent project activities and will allow the FCH community to speak with ‘one voice’• Creation of an interactive web portal for FCH technologies, providing a ‘one stop shop’ for visitors seeking information and acting as a single brand and hub for all other dissemination activities• A cross-European ""hydrogen for society"" roadshow with fuel cell vehicles travelling between cities across the EU. The roadshow will form the focal point for a variety of innovative dissemination activities, public debates, co-hosting of national
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Bioenergy for Europe - a comparative analysis for the community', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Within the European Union, agricultural production for the non-food Bector ib discussed intensively under several aspects as employment in agriculture and other economic aspects, rural development, improvement of the landscape, and sustainable land use as well as important environmental issues, especially search for sustainable energy and deminishing the contributions to global warming. Even if economic or social reasons are judged to be more important than others, environmental impacts are an important additional decision criteria and environmental impacts of the production and use should be minimized. Out of all non-food crops, biofuels seem to have one of the highest potentials. Therefore, the main focus should be set on the whole variety of biofuels. Reasonable decisions in the sphere of environment need a lot of highly differentiated information. The knowledge deficits were pointed out in detail by the Concerted Action 'Environmental aspects of biomass production and routes for European energy supply' (AIR 3-CT942455, the final report i8 due in early 1997) and are summarized in a catalogue of demands.  The proposed project will meet this catalogue - by analyzing all relevant biofuels, - by covering the entire life cycle for each type of biofuel, - by covering data for countries from all parts of the Community, biofuels and countries of production, and furthermore cover social, economic, political, and legal aspects.  Therefore the study will provide . Answers on a high scientific level to which types of biofuels are the best fo the different regions of the Community from the viewpoint of the environment and including socio-economic implications and with that . A high quality environmental related decision base which is needed for a rational promotion of biofuels in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Development of a systems approach for the management of late blight in eu organic potato production' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

Potato late blight causes substantial economic losses in organic production systems throughout the EU. The ban on copper fungicides will substantially increase economic losses to farmers, unless suitable alternative blight management strategies are developed. The proposed project aims at developing improved organic production systems in which potato blight can be managed without or with minimum inputs of alternative interceptive treatments. This will be achieved by development of regionally adapted, blight management strategies based on(I) identification of best current practice in different regions of the EU(ii) variety resistance management(iii) within field diversification strategies(iv) preventative agronomy(v) development and improved formulation/application technology for alternative treatments to copper fungicides.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Artificial Intelligence for early detection of non-communicable disease risk in people with breast cancer' under Horizon Europe.

assistant: **Concept**

The ultimate ambition of the ARTILLERY consortium is to enhance long term health of the growing population of breast cancer survivors by making optimal use of routine imaging for timely detection of actionable chronic conditions or their risk factors. ARTILLERY will develop trustworthy AI systems that allow robust and accurate risk prediction of common chronic conditions, including cardiovascular disease, chronic obstructive pulmonary disease, unfavorable body composition and osteoporosis. Implementation of these AI systems in routine care will provide healthcare professionals with objective and quantitative parameters of their patients’ individual chronic disease risks, permitting them to start prompt treatment and implement risk reducing strategies.Unique aspects of ARTILLERY include the continuous and close interaction between renowned computational scientists, influential breast cancer professionals and the largest breast cancer patient advocacy organisation in Europe, as well as direct access to a large and comprehensive Real-World Data infrastructure that includes CT scans and clinical data from >26.000 patients with breast cancer. This partnership will result in trustworthy AI systems for prevalent chronic conditions, relevant to breast cancer patients and physicians, and ready for implementation at radiotherapy workstations across Europe. ARTILLERY-manuals will be developed and made available to multidisciplinary tumour boards and will contain recommendations on how and when (not) to use AI systems in routine breast cancer care, and on optimal management of breast cancer patients identified to be at high risk of chronic conditions.At the end of the project, we will have augmented the understanding and perception of the public towards the use of AI systems in rou
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'In vitro and In-cell characterization of Quadruplex-duplex hybrids: conformation, folding, and recognition by drug-like ligand molecule'.

assistant: **Objectives**

Nucleic acids are intrinsically polymorphic. Apart from the Watson-crick duplex, guanine-rich sequences can form G-quadruplex  (G4) structures, which have become attractive targets for small molecule ligands. It is now proven that G-quadruplexes can form in cells. Today most biophysical and structural/ligand binding studies are carried out in dilute aqueous solutions and the presence of artificial crowding agents/cosolvents. Still, recent works suggest that the folding of G4s may differ in the cellular milieu context due to the agents' limitations. Thus there is an immense need for in-cell-based structural biology approaches. In the proposal, I aim to address critical milestones leading to the bioactive conformation inside the cell and the development of effective/specific G4 targeting drugs using an essential sub-class of G4 structures as a paradigm, namely quadruplexduplex hybrids (QDH-hereafter). We will focus on low- and high-resolution spectroscopic approaches and mass spectrometry-based ligand screening assays characterizing ligand-QDH interaction. On the methodological part, we will develop in-cell NMR  in ""native"" conditions (starting from unfolded conformation: denovo folding) and propose a ligand screening assay inside the cellular system. Our project will contribute to unveil fundamental principles of nucleic acid folding. It will also foster collaboration between two European institutes specialized in complementary biophysical and structural approaches to study biomolecular folding. In a nutshell, the Maria Skodowska Curie fellowship will flourish my scientific excellence and the resilience needed for my original ideas to become a reality and communication and public engagement skills across cultures and disciplines.""


**Keywords:** NMR, In-cell NMR,  Nu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Enhanced Mass Transport in Electrochemical Systems for Renewable Fuels and Clean Water' under Horizon 2020.

assistant: **Concept**

To meet the growing demand for green energy carriers and clean water for the next decades, we can use the increasing supply of harvested solar and wind energy to synthesize fuels (hydrogen, syngas, ammonia, etc.) and clean water via electrochemical methods. Electrochemical methods have the advantage of single-step, energy-efficient and low-temperature conversion of chemicals. However, despite developments in electrocatalysts and system design in the past decade, none of the electrochemical methods has grown to a market-leading technology in the energy or water sector because of limitations in process intensification. A boost in electrical current density, without sacrificing energy efficiency, is required to allow large-scale deployment.This process intensification needs breaking three limitations in mass transport, at three different scales: 1) the diffusion boundary layer (microscale), 2) gas bubble interference (mm-scale) and 3) concentration gradients in the flow compartments bulk. This ERC project will use a multiscale approach to address these three mass transport limitations, and has the objective to understand and enhance mass transport using novel concepts. Diffusion limitations will be addressed via studying suspension electrodes, gas bubbles will be controlled while synergistically disturbing the diffusion boundary layer via pressure swing control, and reactor engineering concepts that are new to the field of electrochemistry are used to mitigate macro-scale concentration gradients. Water electrolysis, CO2 electrolysis and electrodialysis will be used as tool to evaluate these strategies, using fluorescence lifetime imaging (FLIM) and micro particle image velocimetry (μPIV) to observe the local environment at microscale within large-scale systems. This multis