RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Geophysical Signature of Subsurface Reactive Mixing' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Subsurface reactive processes play a key role in dictating the evolution of subsurface environments, their interaction with surface water bodies and the migration and remediation of transported contaminants. In particular reactive hot spots tend to concentrate in mixing fronts between fluids of different compositions, such as recently infiltrated/injected fluids and resident groundwater, which develop in a range of situations, including CO2 sequestration operations and geothermal systems, contaminant remediation operations, and reactive hyporheic zones beneath rivers. Our understanding of the development and temporal dynamics of these hotspots is currently hampered by the limited sampling offered by boreholes. Recent breakthroughs in geoelectrics may however profoundly change our vision of these phenomena by providing non-invasive techniques with high sensitivity to many geological processes. GeoElectricMixing will hence develop a novel approach to investigate the temporal dynamics of reactive mixing processes from Complex Impedance and Self Potential signals. The coupling of reactive mixing and geoelectrics will be quantified and upscaled by integrating charge transport and polarization phenomena in a new modeling framework, recently developed by the host to predict the spatial distribution of chemical species and reaction rates across mixing fronts (WP1). Dedicated experiments will then be designed by integrating electrodes in a novel millifluidic setup to monitor jointly the temporal evolution of geoelectrical parameters and the spatial distribution of concentrations and reactions rate in a reactive mixing front progressing through the cell (WP2). GeoElectricMixing is thus expected to open a new window on subsurface reactive mixing phenomena, expanding our capacities
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Rheuma Tolerance for Cure' (RTCure).

assistant: **Innovation**

In line with IMI2 goals for improved therapies and precision medicine, the aim of this proposal is to prevent and treat RA or its progression by inhibiting maturation/expansion of pathogenic autoimmune responses through immune tolerising treatments of subjects not only in earlystages of joint inflammation (undifferentiated arthritis and early RA) but also in even earlier defined stages i.e. before onset of joint inflammation, when patients have arthralgia and/or bone loss, or sub-clinical stages of joint inflammation.Today, no drugs are approved for these early phases of RA development, where symptoms such as pain and fatigue cause major loss of life quality and where successful interference would prevent onset of disease. Thus, an important part of our work will be to achieve a better understanding of this as yet unexplored phase of disease. In the proposed project we will develop and validate new methods to identify individuals at high risk for RA, tools to monitor disease progress and expand and further develop cohorts suitable for these purposes.Furthermore we will validate and standardise methods to monitor immune tolerance to be used in clinical trials for tolerising therapies for RA.The aim is thus to interfere with the specific immune reactions that contribute to RA symptoms in such a way that a specific and long-lasting therapeutic effect (ultimately a cure) is accomplished for a major proportion of RA patients and prevention of diseases is accomplished in individuals at high risk for RA.Investigator-initiated as well as company-sponsored clinical trials in well stratified patient groups will be performed in collaboration with SMEs and/or contributing pharma companies and their immune effects studied using the same panel of biomarkers allowing for standardisati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Innovation services and key account management support for Basque SMEs for 2019' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The EU considers SMEs and entrepreneurship as key to ensure economic growth, innovation, job creation and social integration in the European Union. SMEs are the backbone of Europe’s economy since they represent 99% of all businesses in the European Union, employing 93 million people and generating 57 % of value added in the sector. The general macro-economic environment in the EU-28 in 2016 strengthened SME activity in all industries due to the expansion of all categories of final demand. In previous years, the main driver of SME recovery was exports. The year 2016 marked the third consecutive year of steady increases in EU-28 SME employment and EU-28 SME value added. As a result of the recent upturn, EU-28 SME employment has finally recovered from the 2008/2009 economic and financial crisis and even slightly exceeded the 2008 level in 2016. The level of value added generated by EU-28 SMEs showed even greater recovery, at 11 % higher than in 2008. This has also been the trend of Basque SMEs during the same period. Programs supporting SME exports benefit directly only a sub-set of SMEs. However, indirectly, all SMEs benefit to some extent from growth in exports as higher exports raises a) overall income levels, and hence the demand for goods and services sold by domestic demand facing SMEs, and b) the demand for goods and services originating from exporting- oriented enterprises. Some of the main drivers for a high competitiveness score can be linked to the presence of strong skills and innovation capacity and capability, entrepreneurship and easy access to finance. In the Basque Country we are very much aware of this scenario and that is why the Basque Node has designed an implementation plan aiming at contributing to the objectives of COSME. Facilitating access to Euro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Dynamics of Probed, Pulsed, Quenched and Driven Integrable Quantum Systems'.

assistant: **Objectives**

This proposal intends to develop and apply a new-generation theoretical toolbox for understanding the rich dynamics of strongly-interacting many-body quantum sytems subjected to destabilizing manipulations bringing them very far from equilibrium. In atomic systems, condensed matter and nanophysics settings, quantum matter is nowadays routinely pushed beyond the traditional low-energy/linear response/thermal equilibrium paradigms. Some experiments even clearly highlight the need to revise basic fundamental quantum statistical mechanics notions such as ergodicity, relaxation and thermalization in order to explain their behaviour. Theory must thus urgently revise its textbooks and develop new interpretations and capabilities for offering concrete, quantitative phenomenology. This proposal is focused on a set of systems at the very center of this strongly-correlated, experimentally realizable far-from-equilibrium spectacle: integrable models of quantum spin chains, interacting gases confined to one spatial dimension, and quantum dots. Building up on recent theoretical breakthroughs in dynamical correlations and post-quench steady states, this proposal aims to shed a new light on the fundamental principles at the heart of many-body quantum dynamics. It will implement a broad and ambitious research agenda consisting of synergetic projects from mathematically formal thought experiments all the way to phenomenologically applied practical calculations. The types of protocols to be studied include probes creating high-energy excitations, pulses inducing changes beyond linear response, quenches causing sudden global reorganizations, all the way to drivings completely metamorphozing the physical states. The result will be to provide reliable, experimentally relevant and urgently-ne
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Design of motion control chip' (MCC).

assistant: **Concept**

Acquisition of knowledge in VHDL standard language for hardware specification, synthesis and documentation.Reduction of design time from between 6 to 30 weeks down to 2 to 10 weeks.Improved testability reducing failure rate to 25% of current valueImproved reliability and functionality together with 20% reduction in cost.The Application Experiment is TRINAMIC's entry into the field of ASIC design. TRINAMIC's know-how from the development of a range of microcontroller based stepper motor controllers will be used to design an advanced single chip stepper motor controller (MCC). The MCC will be implemented as an ASIC in co-operation with the University of Hamburg using state-of-the-art Cadence DFW-II chip development tool chain which has been in use at the university for several years.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Hybrid Human-AI Decision Support for Enhanced Human Empowerment in Dynamic Situations'.

assistant: **Innovation**

HumAIne will research, develop, validate and promote a novel operating system for Human-AI collaboration, which will enable the development of advanced decision making applications in dynamic, unstructured environments in different industrial sectors. The HumAIne OS will empower AI solution integrators to implement Human-AI collaboration systems that outperform AI systems and humans when working in isolation. HumAIne’s developments will be integrated into a single OS platform, which will coordinate four interwind components offering Active Learning (AL), Neuro-Symbolic Learning, Swarm Learning (SL) as well eXplainable AI (XAI) capabilities. These advanced AI paradigms are ideal for exploiting true Human-AI collaboration since, in each of them, the worker is the key actor with complete control and understanding of the performed operations. AL enables the development of effective Human-in-the-Loop systems that involve humans when AI faces increased uncertainty. Neuro-Symbolic Learning combines DL with semantics and rules to complete highly complex tasks with high accuracy while requiring considerably less training data than current AI models. Advanced XAI models will be made available, providing explanations of models’ predictions while considering the global context instead of just analysing the feature importance of a single AI model. HumAIne’s XAI will provide guidance to humans to  enable the timely optimisation of AL and SL models where human participants provide feedback dynamically as well as fine-tuning of Neuro-Symbolic models. The platform will handle various types of structured and unstructured data, including inputs from humans that will be semantically correlated through ontologies, knowledge graphs, and semantic interoperability. HumAIne will complement its
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'atm-uspacE iNterface and airSpace reconfigURation sErvice'.

assistant: **Innovation**

This project aims to refine and complete the definition of the common ATM U-space interface by identifying new working areas with impact and providing a consolidated interface with a standardized data model, architecture and an operation method to achieve a minimum TRL7. This proposal addresses the topic ATM  U-space Interface and Services which is composed of the following solutions:-Solution 1: ATM - U-space Interface:. Achieve full integration of ATM and U-space systems, by refining and completing the definition of the common ATM U-space interface and identifying new working areas with impact on the already started common interface.-Solution 2: Dynamic Airspace Reconfiguration: Develop the complete service mentioned in U-space regulation and in their respective Guidance Material (GM) and Acceptable Means of Compliance (AMC), necessary to stablish the operating methodology and develop the standard interface to help ATC actors in charge of airspace reconfigurations to maintain traffic segregation and to avoid proximity between manned and unmanned aircraft within the designated U-space airspace.


**Keywords:** This project aims to refine and complete the definition of the common ATM U-space interface by identifying new working areas with impact and providing a consolidated interface with a standardized data
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Minimum environmental impact ultra-efficient cores for aircraft propulsion.' (MINIMAL), addressing dissemination and exploitation.

assistant: **Impact**

Building a sustainable and climate neutral future for aviation is an inevitable requirement for a society with increasing mobility needs. If we are to stabilise the global temperature below the 1.5°C threshold set by the Paris Agreement, rapid action is to be taken. MINIMAL will contribute to a radical transformation in air transport by providing disruptive ultra-efficient and low-emission technologies that will, in combination with the aviation ecosystem, sustainably reduce the climate impact of aviation. The MINIMAL project will, through an unprecedented effort between European engine OEMs, world leading atmospheric physics scientists, and lead researchers in combustion and propulsion, attack the major sources of non-CO2 and CO2 emissions in aeroengines. This will be accomplished with the introduction of climate optimised new propulsion systems based on composite cycle engine technology, that provides unparalleled flexibility with respect to operations, and that has the potential to eliminate the large sources of effective radiative forcing by 2035: 80% reduction from contrails, 52% reduction from net-NOx, and 36% fuel burn reduction resulting in 36% to 100% CO2 reduction, depending on the fuel used.Results will allow assessing the interdependencies between non-CO2 and CO2 effects already during the early stages of aero-thermal-mechanical design and converge into engine options that have minimum climate impact. The findings are supported by numerical (TRL 2) and experimental (TRL 3) proof of concept of Low-NOx opposed-piston constant volume combustion technology with pre-micromixing of hydrogen. In MINIMAL we understand the urgency and aim for maximum impact. Aggressive, but realistic roadmaps will be outlined together with regular exchanges in major industry research
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'On-line Dialysis Sensor Phase2' (OLDIAS2).

assistant: **Innovation**

End-stage renal disease (ESRD) is the most severe form of chronic kidney disease that is an incurable health failure. ESRD is a widespread health issue in developed countries and the patients have only two options: either receive permanent renal replacement therapy or undergo surgery to receive a kidney transplant. There are approximately 3.4 million patients worldwide suffering from ESRD that need artificial methods to replace regular kidney functions in their organism. Currently there are no technologies available that would give adequate feedback in real-time on all the important parameters of treatment quality.Optofluid Technologies (OFT) has set out to introduce an online dialysis monitor that utilizes optical techniques. It has developed a prototype that is able to measure all the important uremic biomarker groups in order to provide detailed feedback on the treatment efficiency. A successful SMEI P1 project has been implemented to carry out a detailed feasibility study and OFT is ready to finalize the development in order to bring the novel device to the market. In order to accomplish this OFT is looking to validate the product performance in clinical setting. To ensure the success of the development EU leading hospitals from 5 different member states have been included to carry out the clinical studies. In addition, the leading experts on uremic biomarkers from the EUTox working group will be involved to ensure effective commercialization and communication activities looking to achieve a fast and widespread market acceptance. The planned project will have a wide-spread economic and social impact by influencing all the key stakeholders – scientific and medical community, patients and dialysis equipment manufacturers. As a result of the development project, OFT wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Tropical forests and climate change: understanding links to predict future responses' (TROFOCLIM) under Seventh Framework.

assistant: **Objectives**

Tropical forests cover just 7% of the Earth s surface, but store 25% of the global terrestrial carbon pool. Since they are so rich in carbon, net loss or uptake of carbon by tropical forests has important implications for atmospheric CO2 levels. Thus, tropical forests can speed up climate change by net emission of CO2 or slow it down by net sequestration. The rise in atmospheric CO2 level since the onset of the Industrial Revolution and the resulting climatic changes have certainly affected tropical forest dynamics. Understanding the impacts of these changes so far is crucial to predict future responses. Recent studies have shown that tropical forests have acted as carbon sinks over the last decades. However, it is unclear whether these forests have accumulated biomass already over the longer periods of time during which CO2 levels have risen and climate has changed. It is also unknown what has caused the observed biomass increase. The proposed study has the objective to detect, explain and predict long-term climate change effects on tropical tree dynamics. To this end, I will apply three techniques which are new to this field: tree ring analysis, stable isotope measurements and tree growth modelling. This is the first pan-tropical study that analyses centennial-scale tree growth. The study will be conducted at three sites (Bolivia, Cameroon, Thailand) and includes 15 tree species. I will test for gradual changes in long-term tree growth using tree ring data. Stable isotopes (C, O) will be measured to reconstruct past climate and detect responses to CO2 rise. The influence of changes in forest dynamics on tree growth will also be assessed. Finally, I will develop and apply physiological tree growth models and population models to unravel the complex interactive effects
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Monitoring cancer heterogeneity based on the dynamic assessment of the Warburg effect under metabolic perturbation' (CHyMERA).

assistant: **Innovation**

Cancer heterogeneity is reflected in the multitude of phenotypes found in the clinic, with different proliferation statuses and metastatic potentials. These features cannot be assessed with the molecular imaging methods commonly available for diagnosis and monitoring. The main goal of this proposal is to develop a molecular imaging methodology based on endogenous contrast – CHyMERA – and demonstrate its feasibility to image hotspot areas of active proliferation and metastatic potential. The approach is based on the concept of cancer metabolic plasticity, does not require contrast agents or radioactive tracers, and should ultimately provide more specificity to cancer diagnosis and treatment planning than other imaging methods currently available. We propose to use animal models of human cancer, a glucose-enhanced imaging method, and an objective analysis of regional metabolic responses to controlled, reversible changes in the tumour microenvironment (perturbations), such as transient hypoxia. Specifically, we will (i) develop and validate CHyMERA at ultra-high magnetic fields, to monitor the metabolic kinetics of glucose and lactate in the tumour microenvironment. This methodology will be (ii) applied in vivo to two immunocompetent mouse model of GBM (allograft and genetically engineered models), to image vascular permeability/perfusion and hotspots of glioma proliferation. Finally, we will (iii) carry out a pilot study with two isogenic mouse models breast of cancer, metastatic and non-metastatic, to generate hotspots maps of proliferation and metastatic potential. All in vivo results will be validated post-mortem by immunohistochemistry. If successful, this methodology has a strong potential for clinical translational, which the host institution is ideally suited to te