RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'SMART BONE REGENERATION' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The management and reconstruction of bone defects is a significant global healthcare challenge. While autografts offer ideal compatibility, they are often not suitable for large bone defects, and allografts suffer from potential immunorejection.The limited efficacy of conventional treatment strategies for large bone defects and the increasing aged population, has inspired the consortium to propose a SMART RESORBABLE BONE (SRB) IMPLANT embedding stem cells and bioactive agents with the aim of a controllable and fast restoration. The proposed solution includes 3D printed medical grade polymers enriched with electrospun fibers (for increased mechanical properties) that can be customized for patient physiology, pathology, and gender. The scaffold design will ensure easy and minimal Injury placement,  and will embed different sensors for monitoring e.g. pressure, pH value and temperature based on biocompatible conductive inks. The smart implant will thus be able to provide vital information of implant performance in terms of bone growth and infection/inflammation. The proposed method is unique because it includes a customized smart implant (3D printed parts with adjustable sensors and communication electronic system), together with tissue engineering methods i.e. in-vitro programming of stem cells for embedding into the smart implant. The proposed solution introduces an innovative regenerative chain, from early testing and characterization (identification/adjustement of the proper specifications) and embedding regenerative stem cells and particulate bioactive agents into the smart implant in preclinical research (in-vitro). The in vivo proof of concept of SBR solution will be tested in (large animal model) preclinical studies within the scope of the project. Finally the regu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The role of knowledge in the construction and regulation of health and education policy in Europe : convergences and specificities among nations and sectors' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

In Europe, information and expertise are now more widely available and distributed than ever before. At the same time, expectations of transparency and public accountability have increased. In turn, the legitimacy of political processes depends on the legitimacy of the knowledge on which they draw. Both social cohesion and effective government depend on integrating knowledge as well as interests.Responding to this new reality, the research is organized around three complementary orientations. Orientation 1 seeks to map the knowledge potentially available to decision makers, and trace the relationships between those who hold or produce such knowledge and those who take policy decisions. Orientation 2 analyses decision-making processes as such, paying special attention to the way information and understanding are deployed and learning takes place at different stages.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Statistical analyses and composite indicators in research and innovation' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The study has FIVE foci of interest:1)to better understand the sectoral and cross-country differences in fast-growing enterprises in Europe2)To investigate the role of research mobility in steering research excellence, by analyzing the impact of researchers’ inflows, outflows, and “turbulence” (inflows + outflows) on the citation impact or research excellence of universities and other research organizations3)to explore the location determinants of foreign direct investments in R&D at the regional level in EU-28 countries4)to provide support in the improvement and refinement of existing indicators to measure research excellence and innovation output5)to investigate the impact of EU research funding initiatives on the production of excellent research.


**Keywords:** Indicators, Composite indicators, Innovation, econometrics, fast-growing firms, research excellence, mobility, EU funding
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Deciphering the logic of representational drift and its conversion to stable readouts.' under Horizon Europe.

assistant: **Concept**

We perceive the world around us as constant. When we engage in the same action over days and weeks, for instance when we walk down a familiar road, it feels the same every day. Neurons build a model (or representation) of the external world that is thought to guide behaviour. However, neural representations change over time, leading to a restructured model of the world. This phenomenon, called representational drift, has been identified across a range of brain regions and behaviours, and poses a conceptual challenge: How can changing neural correlates of external variables be reconciled with perceptual stability? This proposal aims to decipher this discrepancy. We recently showed that the medial prefrontal cortex (mPFC) displays little representational drift when mice are engaged in an olfaction-guided memory task. Interestingly, upstream sensory regions relaying olfactory information to the mPFC show prominent drift. These results suggest that drifting codes early in signal processing are converted to a more stable code in the mPFC. Using the primary olfactory cortex to mPFC signal chain as model system, DRIFT-rules aims to systematically map out the extent of representational drift in the mPFC and its upstream partners under conditions of varying computational demands for the mPFC circuitry. Using 1- and 2-photon calcium imaging and chronic electrophysiological recordings with Neuropixels probes in awake mice, we will determine drift during different behaviours, in which the animals rely on olfactory cues to solve distinct cognitive problems. Combining large-scale neuronal activity measurements with novel computational techniques, we will reveal how mechanisms on the level of single cells, microcircuits and neuronal populations contribute to the conversion of drifting
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Catalytic Asymmetric Reductive Amination of Ketones' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The need for direct catalytic transformations with economy of matter, solvent and catalyst is a challenge for modern chemistry towards clean and environmentally friendly processes. The objective of this project is to perform the enantioselective reductive amination of ketones in one pot without isolation of intermediates by using multi-functional catalysts, which should be able to promote condensation of an amine with a ketone, and catalyse the enantioselective reduction (hydrogenation) of prochiral unsaturated intermediates to give optically pure amines. This type of compounds would find immediate applications as ligands for other catalysed reactions, and as intermediates for fine chemistry.   R1R2C=O   + H2NR3   +   H2   ________________>   R1R2C*H-NHR3   + H2O  This innovative procedure presents tremendous advantages over the strategy, which is most often used at the moment and involves at least three independent steps (ketone transformation into enamine derivative, enantioselective hydrogenation, deprotection). This will be attempted by using transition metal catalysts (Ru, Rh, Ir) associated to optically pure ligands and eventually additives. Metal complexes containing bidentate ligands should be tested under specific conditions. The innovation will be in the design and preparation of new precursors of catalysts bearing less traditional ligands and specially monodentate phosphorus ligands such as phosphites, phosphoramidites, diaminophosphites. The expertise in molecular catalysis including asymmetric catalysis and the equipment in the host laboratory, that is participant in a European NoE,  provide all the favourable conditions for the achievement of this goal, and good training of the Marie Curie fellow.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Highly efficient, solar-powered irrigation pump'.

assistant: **Innovation**

Ennos is a Swiss company founded in 2006 as a spin-off of Berne University of Applied Sciences under the lead of Prof Dr. Andrea Vezzini, who has a long track record in solar energy and motor drive systems. We are an interdisciplinary team of experienced engineers and marketing experts, who have dedicated our efforts to develop and demonstrate sunlight2.0, a second generation of highly efficient, portable solar-powered irrigation pumps targeted for smallholders in isolated rural areas. There are more than 570 million farms in the world, most of them being located in distant rural areas. Out of those farms, about 84% are smaller than 2 ha. Nowadays, bigger crop areas have to be put under irrigation to increase productivity due to a growing population that has to be fed. This implies a growing need for energy and water resources. Besides, 16% of the global population did not have access to electricity in 2016, mainly in rural areas where the majority of smallholders are located. Therefore, smallholder farmers need competitive solutions, economically affordable and efficient and that enable them to increase their profits. sunlight2.0 is a portable and user friendly pump which is highly efficient and affordable to smallholders. sunlight2.0 has almost no maintenance costs and allows farmers to save the cost of diesel or electricity producing zero emissions. During Phase 2 project we expect to increase the efficiency of the pump, reduce weight and optimize production costs compared to our previous sunlight1.0 product. Completion of Phase 2 project and will require €1 million investment, that will provide an estimated ROI of 5.7 by 2025.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Transnational Book Diplomacy beyond the Cultural Cold War: Towards a Socio-Cultural History of the Tamizdat'.

assistant: **Concept**

The transnational production, circulation and reception of Soviet and East European literature in the West during the Cold War challenges the dominant two-bloc narrative and tells us a different story about the cross-border flow of knowledge and ideas. Focusing on the intense cultural exchanges of the time across and beyond the ‘Nylon Curtain’ –an ideological and geopolitical border extremely permeable to cultural objects– this research project aims to challenge: 1) the traditional representation of Western and Eastern cultures as divided into two isolated blocs and 2) the representation of tamizdat as a mere ideological weapon of the ‘Cultural Cold War’. The term TAMIZDAT (‘published abroad’) refers to Soviet and Eastern European texts, unpublished in the Eastern bloc and clandestinely smuggled and published in the West. As an alternative transnational publishing practice with a specific socio-cultural value, tamizdat highlights «cooperation across apparent ideological division and cross-border interaction instead of hostility» (Mikkonen, Scott-Smith et al. 2019).  The «emphasis on smaller national and transnational actors instead of governments» (ibidem) demonstrates the crucial role of book diplomacy in preventing the cultural isolation of the two blocs.  Following O. Sanchez-Sibony, who questiones from a socio-economic perspective the representation of the Cold War as a bipolar contest between superpowers (2014),  I will address the socio-cultural dimension of this narrative. Treating tamizdat as the result of socially and culturally regulated activities, I will consider the agency of social (activists of social movements, dissidents, Soviet and East European émigrés, diplomats etc.) and cultural actors (writers, editors, translators, literary agents, critics, journ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'PainDynamics: Research on the dynamics of attention bias for pain in daily life.' to be submitted under Horizon 2020.

assistant: **Abstract**

Chronic pain is a major health care problem in Europe which results in huge economic costs. Available cognitive-affective accounts of pain, distress and disability suggest that attention plays a pivotal role in the development and maintenance of pain problems. In particular the presence of an attentional bias towards pain-related information (AB) is thought to initiate or exacerbate pain problems in chronic pain patients. Despite the intuitive appeal of this idea, findings are inconsistent. In the current project I argue that inconsistent findings in AB research are due to both conceptual and methodological limitations of previous research. From a conceptual standpoint, I argue that the presence of inconsistent findings is owe to the conceptualization of AB as a stable trait-like or habit-like process. Instead, I propose to conceptualize AB as a temporally dynamic, fluctuating and enfolding phenomenon that varies over time and across contexts. From a methodological standpoint, I furthermore argue that varying empirical support may also be due to limited ecological validity in AB research. I propose that the ecological validity could be increased by using somatosensory stimuli instead of linguistic stimuli and by investigating AB for pain-related information and key variables in everyday situations instead of in a single laboratory session. In the current proposal, I will address these conceptual and methodological challenges via (1) the development and validation of a novel ecologically valid paradigm to assess AB, and (2) an investigation of key hypotheses concerning the role of AB in chronic pain using a novel ecologically valid approach. Increased understanding of the occurrence, dynamics and implications of AB in varying daily life contexts represents an important s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'UnRAVElling the dynamics of many-body open systems: Collective dynamics of quantum trajectories' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

With the flourishing of quantum information processing, the study of open quantum system dynamics has become of paramount importance for the ultimate success of quantum technologies. The phenomenology becomes increasingly rich when decoherence and dissipation arise in quantum systems with many degrees of freedom, leading to a flurry of different phases of matter. RAVE is devoted to the study of collective phenomena in synthetic, many-body open quantum systems through investigation of the dynamics of quantum trajectories. Following the dynamics at the level of its trajectories will capture features that are washed out by looking at averaged observables, i.e. in the density matrix.   RAVE will show that there are collective phenomena visible only in the dynamics of single trajectories, and propose experimental schemes to observe them. This will lead to a new classification of phases in quantum many-body open systems and help clarify the relations between entanglement, correlations and non-equilibrium thermodynamics. In those cases where the steady-state phase breaks time-translational invariance, RAVE will contribute to unify apparently different concepts such as synchronisation and time-crystals.    The statistics associated with the behaviour of quantum jumps in many-body systems is also important for characterizing the quality and performance of quantum information processing protocols.  To address the key questions posed by the project, RAVE will develop a promising new methodology based on replicas and use it to design open system quantum simulators able to provide information at the level of single trajectories. RAVE is a highly interdisciplinary programme which will have significant impact in the fields of condensed matter, statistical physics, quantum information
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Molecular mechanism of empathy' (MOLEMPATHY).

assistant: **Innovation**

Empathy plays a fundamental social role, allowing the sharing of experiences, needs, and goals across individuals.  Anxiety, posttraumatic stress disorder, autism, Asperger's syndrome and some cerebral damage are often characterised by an inability to empathise with others. Some studies of animal behaviour claim that empathy is not restricted to humans, and even rodents have been shown to demonstrate empathy for cagemates in pain. It is very likely that pro-social behaviour has neurological and neurochemical basis. Although recent fMRI studies on humans revealed that experience of empathy connected with activity of several regions in cerebral cortex, the molecular mechanism of empathy is still poorly understood. The current project is aimed to study the signal transduction pathways in brain involved in empathy. Given the intrinsic difficulties associated with such studies in human beings, here it is proposed to use an animal model, namely mice acutely treated with low dose of empathogens-entactogens, pharmacological agents that able to increase empathy, emotional sensitivity, loss of social inhibitions, reduced anxiety and an increased sense of closeness with other. Alteration in gene/protein expression profile of mouse cerebral cortex after single administration of widely used empathogen 1-(1,3-benzodioxol-5-yl)-N-methylpropan-2-amine will be investigated by methods of differential transcriptomics and proteomics. The co-administration of selective antagonists for 5-HT1a and oxytocin receptors, have been reported to regulate pro-social behaviour, will allow to distinguish between empathogenic and adverse effect of 1-(1,3-benzodioxol-5-yl)-N-methylpropan-2-amine. This study will further improve our knowledge about molecular mechanisms of empathy, and, possibly, may assis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Prague centre of mathematical geophysics, meteorology, and their applications' under Fifth Framework.

assistant: **Concept**

The proposal aims at increasing international recognition of geophysics and meteorology at the Charles University in Prague, and to finalise integration into the European Research Area. The proposing team has long tradition in research and education of the solid Earth and atmospheric dynamics. The innovation will consist in networking European researchers by means of organizing workshops, inviting lecturers, and hosting PhD students and post-docs. The research will be applied to environmental problems, such as climate change, pollution transport, earthquake hazard, and the energy problems, such as the oil exploration. The Centre will be based on strong existing international co-operation (including EC and NATO projects, and third-party projects with major oil companies). The national socio-economic impact will be mainly in the air-pollution studies. The Centre will increase attraction of the Earth's science studies for Czech students.