RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Pilot line for micro-transfer-printing of functional components on wafer level' (MICROPRINCE) targeting Horizon 2020.

assistant: **Abstract**

The “Pilot Line for Micro-Transfer-Printing of Functional Components on Wafer Level” project (MICROPRINCE) is focused on creation of a pilot line for heterogeneous integration of smart systems by micro-transfer-printing (µTP) in a semiconductor foundry manufacturing environment. Functional components like processed III/V devices, optical filters, and special sensors will be transfer printed to demonstrate the capabilities of the technology and pilot line. Based on several EU and national research activities demonstrating successfully the feasibility of µTP technology in a scientific and laboratory environment, the MICROPRINCE consortium has the goal to setup the first worldwide open access foundry pilot line for heterogeneous integration by µTP and to demonstrate its capability on five defined target application scenarios. For this purpose, the consortium consisting of 13 partners from four different countries combine their expertise along the value chain from materials and equipment, technology and semiconductor processing, integrated circuit and system design, test and application. The partners are industrial companies incl. SME’s, accompanied by leading research institutes with a clear focus on production and application in Europe. The working principle of the micro-transfer-printing technology is to use a micro-structured elastomer stamp to transfer microscale functional components from their native substrates onto non-native substrates. The lateral dimensions of the functional components can range from a few microns to a few hundreds of microns with thicknesses of only a few microns. The native substrate contains the functional components to be printed and is flexible in size and material. The MICROPRINCE pilot line is acting as a regional and nationwide competence
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'One-step switchable fluorescent probe assay for direct virus detection.' (1-SWITCH) targeting Horizon 2020.

assistant: **Abstract**

Since March 2020, the world is facing the Covid-19 pandemic. As of September 2020, over 900 000 people have died of the disease, caused by the SARS-CoV-2 virus. The WHO recommendations in order to limit the spread of the virus are to “test, trace and isolate”. To be successful, this strategy requires fast and massive testing. Today, tests are performed using PCR, a resource-intensive process requiring extraction of the viral RNA before nucleic acid amplification. PCR tests are slow (several hours) and require an army of advanced laboratory equipment or automated diagnostic workflow setups for the various steps, and thus prevalent in centralized facilities testing samples in large batches. Consequently, the turn-around time for these tests has proven to be 24-48 hours globally. Here, we propose to develop a new Covid-19 test, 1-SWITCH, consisting of a single step switchable fluorescent probe assay. The 1-SWITCH technology will use low cost reagents, and therefore will be cheaper than current available Covid-19 tests. The sensitivity of the test will be superior to the one of antigen tests and comparable to the one of PCR tests. This 1-step, 1-tube method will detect the virus directly within minutes and eliminates the assay complexity, thus facilitating smoother workflows in laboratory diagnostics as well as point of care screening. This will consist of a major breakthrough in clinical diagnostics. Plans for bringing our research finding to a commercial innovation are presented.


**Keywords:** virus detection, SARS-Cov-2, direct detection, high sensitivity, low cost
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'The Plurality of Fontenelle's Worlds. Translations, Transfers of Knowledge and Natural Philosophy in Europe (1687-1788)' (1687-1788).

assistant: **Innovation**

PLURIFONT focuses on the single greatest astronomical bestseller of the eighteenth century: Bernard de Fontenelle’s Entretiens sur la pluralité des mondes (1686), and its Italian, German and English translations as one interconnected case study, to be addressed from a transnational European perspective. I seek to appraise the several versions of the Entretiens over a timespan going from 1686 to circa 1780 as interventions in cross-linguistic and cross-cultural conversations on natural philosophy, while recovering the agency and voices of translators mostly unknown to present historiography. By addressing the wider topic of the production of translations as means of transmission of knowledge in the long eighteenth century, my main purpose is to examine some of the debates on natural philosophy at the core of the Enlightenment period in an innovative way: by reconsidering the traditional approaches employed within the interdisciplinary field of translation studies. My working hypothesis contends that the Entretiens constituted an open, flexible and porous ‘site of knowledge’ that travelled temporally and geographically across Europe, providing fertile ground for its many translators to revise the scientific ideas of the ‘source’ text through a wide range of paratextual devices and to adapt them to the debates of their times. As a result, these translations became conflictual sites of knowledge, conceptually removed from the original work, while remaining the vehicles of heterogeneous scientific discourses usually dismissed by the simplified narratives of ‘progress’ associated with Enlightenment’s historiographies.


**Keywords:** Translation studies, natural philosophy, circulation of knowledge, Enlightenment studies
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Elucidating the networks of immune stromal connections by Perturbation of Immunity in Cancer - towards developing novel therapeutic strategies' (EPIC).

assistant: **Innovation**

Immune cells monitor and eliminate cancer cells, and thus keep tumors in check along the lifespan of an organism. However, tumors have evolved various mechanisms to avoid immune surveillance. Therefore, understanding these mechanisms and interfering with them to facilitate immune cell eradication of tumor cells is the focus of many successful immunotherapies. However, the efficacy of immunotherapy is limited to only a small fraction of patients and only certain types of cancers. Therefore, it is crucial to understand the immune-tumor interactions to develop new treatments. Moreover, tumor evasion mechanisms interfere with such treatments, as compensatory programs ensue soon after therapeutic intervention. These compensatory programs are not limited to tumor cells, but also occur in the stromal compartment of the tumor microenvironment (TME), which provides indispensable support to the tumor, and is often overlooked as potential target for intervention. Here we aim to gain a fundamental understanding of all cellular networks within the TME, to elucidate the roles and programs carried out by each cellular element participating in the complex, multilevel interactions that occur before therapeutic intervention and afterward. Toward this goal, we will map the entire spectrum of immune and stromal cell interactions in the TME. We will identify negative- and positive-tumor-regulator dependent programs, primary and compensatory, unique and shared-across pathogenic conditions, and cell-intrinsic and extrinsic programs (Aim 1). Additionally, we aim to identify conserved mouse and human pathways using a parallel mouse and human tumor slice culture system (Aim 2). Based on Aims 1 and 2, we will test and validate new candidates for targeted rational combination therapy in-vivo (Aim
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'TRANSFORMING ACCESS TO EXCELLENCE WITH SUCCESSFUL ALLIANCES OF HIGHER EDUCATION IN DIGITAL AGRICULTURE', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Widening countries lag behind the European average in Research & Innovation investment and scientific excellence; the domain of Digital Agriculture (DA) is one prominent example. Higher Education Institutes (HEIs) of Widening countries, like Greece and Serbia, can play a central role in addressing this issue, but need support for achieving excellence in research and education in the DA domain. HEIs in Belgium have gained significant experience by establishing an ecosystem that fosters close collaboration among HEIs, competence centers, Digital Innovation Hubs, and industry, leveraging advanced digital technologies for the benefit of citizens, business, and scientific advancement. In this light, TALLHEDA will build a new long-term Alliance for DA between agricultural HEIs from Widening countries with leading non-widening agricultural universities, and local and international stakeholders. TALLHEDA Alliance will contribute to raising the critical mass of highly skilled scientists and to establishing liaisons with surrounding ecosystems, in order to foster the Quadruple Helix of innovation in Widening countries.The path to excellence will be paved with a portfolio of multi-actor, inter-sector and international complementary actions to support students, early-stage and experienced researchers, and academic staff of the Widening HEIs. This will be achieved through collaboration, complementary top-level expertise of all partners, access to cutting-edge infrastructure, staff mobility, and joint educational and research activities. The partners have an established scientific reputation in DA and are committed to making TALLHEDA a success.In the long term, Widening HEIs will be one step closer to reforming their institutions in terms of content and quality of educational courses
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'CONSTRUCTION AND OPTIMIZATION OF A NOVEL, ULTRA-COMPACT, ULTRA-FAST HARD X-RAY COHERENT SOURCE' (NOVELXSOURCE).

assistant: **Concept**

Laser Wakefield Acceleration (LWFA) of relativistic electron beams, and High Harmonic Generation (HHG) are two of the driving applications of high-power, short-pulse laser interactions with matter.Quasi-monoenergetic relativistic electron beams can be produced when short laser pulses are focused at intensities exceeding 10^18 W/cm^2 on usually low-Z gas targets. The gas is instantly ionised and a non-linear plasma wave is created. For sufficiently large amplitude plasma waves, the wave breaks, injecting electrons inside the plasma wave where they are accelerated, so far up to energies > 1 GeV within ~ cm. However, high-Z trace elements can be further ionised at close to the peak of the laser pulse, thus releasing more electrons into the plasma wave. These ionisation-injected electrons are accelerated due to the open trapped Hamiltonian curves they lie on. This can significantly reduce the laser requirements for injection and so acceleration can proceed in a more controlled fashion.HHG occurs when a ~1mJ, ~10 fsec laser is focused on a neutral high-Z gas jet. The bound electrons of the atoms move in response to the ultrafast oscillation of the laser’s electric field. Harmonic photons up to keV energies, are produced through the recollision of the accelerated (but not ionised) electrons with the parent atoms. Novel experiments using multiple gas jets and a combination of different Z gases, has shown an increase in the conversion to high harmonic as well as the control of their coherence.This research proposal will focus on optimising ionisation induced LWFA production of electron beams, producing high harmonic photon beams from novel gas targets, and finally counter-propagating the two beams, so as to produce a novel, ultra compact, ultrafast, high-energy, hard x-ray cohe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Ciliates as monitors for environmental safety of gmo' (CIMES).

assistant: **Innovation**

One of the major concerns limiting the potential usage of genetically modified crops and organisms in agriculture is the potential risk for lateral gene transfer in the environment. While numerous studies have considered lateral gene transfer into gut bacteria, the transfer into unicellular eukaroytes has been ignored until now. Here we propose that the unique genome organisation of ciliated protozoa, i.e. the presence of an asexual macronucleus with gene-sized mini-chromosomes, makes them ideal bio-monitors for gene transfer events in the gut of farm animals and insects. The telomeric sequences of gut ciliates plus signature sequences in GMO-derived DNA should allow primers to be developed for bulk DNA analysis by PCR and high throughput screening using fluorescence in situ hybridisation and flow cytometry. These transfer events will be compared to historical gene transfer event evaluated by bioinformatical techniques.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'CROR Engine Debris Impact SHielding. Design, manufacturing, simulation and Impact test preparation' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

New, eco-efficient aircrafts are challenged by a demand to significantly reduce the CO2 and NOx emission. To achieve these goals, the topic manager is exploring new configurations for integrating advanced engines and propulsion concepts to the aircraft. Most of such promising concepts as the CROR-engine, Boundary Ingestion Layer (BIL), Ultra High Bypass Ratio engines (UHBR), multiple fan cannot be targeted simply by replacing engines of the current generation, but require a substantial change of the principle aircraft configuration.In case of un-ducted engine architecture as the CROR, the rearward shift of the engines away from the wing provides additional advantages in cabin noise and passenger comfort and safety improvement.Regarding the safety, main issue is the CROR engine debris that can be release with high energy when there is a failure. It is mandatory to develop innovative solutions for panels and shielding able to shield and reduce damage at impact, to secure the airframe integrity, so that aircraft can make safe continuation of flight and landing after engine burst event.The goal of REDISH is the development and maturation of innovative shielding able to sustain impacts from high and low energy debris caused by CROR engine burst. A coupled experimental-numerical development approach at two structural scales (laminate/panel and component) is proposed that starts from a large pool of possible configurations that will be downselected in successive analysis steps of increasing detail. Virtual testing by means of high-fidelity simulation tools developed by the consortium will be used to decrease the need for costly physical testing as much as possible and accelerate the shielding development process. The specimens to be manufactured and tested are the ones strictl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'A second metagenomics generation to better understand plant virus ecology and evolution' (GEOMETAGENOMICS) targeting Seventh Framework.

assistant: **Abstract**

Understanding the dynamics of viral diversity at interfaces between preserved and cultivated areas is a necessary major step towards understanding the molecular evolutionary processes underlying the emergence of plant viruses as agricultural pathogens. This project is likely to yield large volumes of novel information both on natural viral diversity associated with threatened ecosystems, and on the impact of human mediated disturbances on this diversity. Our first objective is to decipher contemporary plant viral dynamics within a defined spatiotemporal framework located in the fynbos biome of South Africa, and to assess the impact of fire and agriculture upon fynbos plant viral biodiversity. Our second objective is to retrieve virus sequences from preserved herbarium specimens to analyze past viral diversity. Our third objective is to specifically target an entire virus family (Geminiviridae) in order to understand the evolutionary processes by which geminivirus have emerged over the past two centuries to become important crop pathogens. During the colonization era these viruses jumped from their indigenous African hosts into the exotic crop species introduced by Europeans. Following adaptation to these hosts some of these newly emergent virus strains spread across the continent to become what are today among the most important biotic threats to African food security. During the outgoing phase, I will be joining Dr Martin’s group (Univ. of Cape Town), who has an extensive track record in both the experimental and computational analysis of virus evolution and genetic diversity. I firmly believe that this project will be the first step in my development as a world-leader in the field of virus evolutionary-ecology research that could credibly apply for and obtain ERC Adva
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Luminescent liquid crystalline materials based on metal clusters'.

assistant: **Concept**

The “MESOCLUST” project, which predominantly addresses fundamental research but also aims to take the benefit of further industrial applications, explores a completely new concept regarding the liquid-crystalline materials, namely CLUSTOMESOGENS, reported for the first time in 2010 (Angew. Chem. Int. Ed. 2010, 49, 3351).The main objective of this proposal is the design of new hybrid materials showing liquid crystalline properties as well as bright luminescence in the red-NIR range by coupling metallic clusters with mesogenic units. The metal atom cluster has two important roles: on one hand, can control the self-organization process of the material, and, on the other hand, add its intrinsic properties (luminescence, magnetism, redox) to the final material.  Among the different families of metal clusters, octahedral clusters (Mo6 and Re6) were retained for this proposal because of their wide range of physical and chemical properties and, in particular, for their luminescence properties.The novelty of this work consists in compensating the lack of processability of M6 clusters synthesized by solid state chemistry (essentially due to their ceramic-like behaviour in the solid state) by designing nanohybrid inorganic-organic materials that subsequently show liquid crystal properties. It allows therefore their self organization at the molecular scale by a simple heating-cooling process. This project will give more opportunities to the host group to stay the leader in the field at the international level. Although at a first glance, the work is of peculiar interest to academics from a range of backgrounds, in particular to supramolecular, coordination, solid state and material chemists as well as physicists, there is a considerable industrial and commercial potential in the me