RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'MIcrovascularizED Tumour-on-chip for Cellular ImagiNg of Drug Response and Cell moTility' under Horizon 2020.

assistant: **Concept**

MImETIC INDiRECT aims to develop a standardised, accessible, versatile organ-on-chip toolkit for cancer biology and drug discovery research, compatible with microscopy-based (live imaging and confocal) techniques. The project is expected to facilitate academia and industry adoption of microfluidic 3D cell culture systems for comparable and reproducible results in a complex biomimetic animal free model for cancer drug discovery, toxicology, advanced (pre)clinical as well as personalized medicine. The toolkit components will consist of an integrated temperature controller dual-chamber chip, the Cherry Biotech CubiX system and growth factor optimized collagenous solutions for each chip chamber. The dual chamber chip, with cellular migration lanes, will have two tailored collagen-based formulations, designed per chamber. The CubiX platform is a compact flow and temperature controller, allowing optional sensor (e.g. O2) integration, compatible with single chips or 24-well plates. The cancer(s) sub-types to be used toolkit standardization will be dictated by market needs, where commercial cell lines (cancerous and non-cancerous) will be used to create the microvascularized complex tissue model.  Potential project risks have been identified with appropriate mitigation strategies, where the project promotes adoption of standardized, cost-effective and versatile cancer organ-on-chip platforms in the market, rather than disruptive academic findings.  Access of the aforementioned system to a worldwide growth market will fully exploit the project results, disseminated by direct and indirect marketing and scientific approaches. Project implementation will be an academic-industry collaborative and multidisciplinary manner providing the acquisition of diverse and unconventional comple
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Cooperative and Interconnected Green delivery solutions towards an era of optimized zero emission last-mile Logistics' (GREEN-LOG) under Horizon Europe.

assistant: **Objectives**

GREEN-LOG accelerates systemic changes in last mile delivery ecosystems for economically, environmentally and socially sustainable city logistics. The project establishes city platforms comprising of inclusive stakeholder Urban Living Labs for nurturing social innovation, designing and deploying innovative delivery solutions while allowing the most effective exchange of ideas, the development of robust, harmonized regulatory and policy frameworks, and cooperative business models that build upon effective public/private-sector collaboration and joint investments. The GREEN-LOG approach provides an innovative simulation environment for scenario building combining different solutions that allow the integration of last-mile delivery interventions with the highest possible impact on environmental sustainability and traffic reduction, while considering their financial viability. On the operational level, GREEN-LOG provides cargo-bike based innovations for sustainable micro-consolidation design and deployments, multimodal parcel deliveries integrating public transportation, Logistic as a Service platforms for interconnected city logistics and automated delivery concepts with the use of autonomous vehicles and delivery droids. The solutions are supported by interconnected city logistics dataspaces that feed dynamic services for proactive optimization of the ecosystem, respecting the interests of consumers, businesses and city stakeholders. The approach is deployed and validated in five cities and areas: Athens, Barcelona, Flanders, Oxfordshire and Ispra. Special focus is given on the transferability of the proposed innovation, starting from three follower cities with high interests in tailoring and replicating the GREEN-LOG solutions, and continuing with a pan-European outreach
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Health and the Understanding of Metabolism, Aging and Nutrition' (HUMAN).

assistant: **Concept**

Recently intense research identified around 4,000 single nucleotide polymorphisms (SNPs) associated with human age related diseases such as metabolic disorders. Despite their highly significant association to pathology, the functional role of these genetic variants is, in most cases, yet to be elucidated. The evolutionary distance of most animal models from humans represents a major limitation for the functional validation of these SNPs. To overcome these difficulties, HUMAN will generate mouse models carrying human hepatocytes or pancreatic βcells from either primary cells (hepatocytes) or induced pluripotent stem cells (iPSCs). This innovative approach offers the unique possibility of studying function of genetic risk variants associated with metabolic diseases in an integrated living system (the mouse body), but within human-derived organs, i.e. liver and pancreas. iPSCs used to generate hepatocytes and βcells will derive from extreme phenotypes, i.e. patients affected by severe metabolic diseases such as type 2 diabetes (T2D) or subjects selected for exceptional healthy longevity (subjects over 105 years and offspring of nonagenarian sibships) all fully clinically and metabolically characterised and genotyped; they will be selected according to the best combination of risk and protective alleles. We will test the effect of different nutritional regimes (e.g. high fat diet, caloric restriction), to disentangle the complex molecular mechanisms and circuitry across organs  (e.g. hypothalamus-liver axis) which lead to pathology. HUMAN associates a core of outstanding basic research institutions to leading European biotech SMEs, and has the capability to produce at least 500 humanised mice. HUMAN will generate iPSCs biobanks and comprehensively manage all associated in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Free Information Geometry' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

This project will develop an information geometry for free probability theory.  Free probability is a theory of non-commuting random variables that describes the large-n behavior of many families of n x n random matrices.  Free probability has had applications to data analysis, communication, finance, and many other topics where matrices appear, as well as to the structure of von Neumann algebras, which is a wide-ranging and challenging field of pure mathematics.  Information geometry refers to the synthesis of optimal transport together with measures of information such as entropy, which has shaped much recent work in partial differential equations, optimization, and data analysis.  Information geometry has motivated many corresponding results in free probability theory, but several deep questions remain open concerning the relationship between optimal transport and entropy in free probability, and whether it accurately describes the large-n limit of the classical information geometry for random matrices.  This project aims to show that free entropy is concave along optimal transport geodesics, establish the existence of momentum measures in free probability, give an optimal control formulation of free entropy, and exhibit counterexamples to regularity properties for optimal transport through connections with quantum information.  The project will be supervised by Magdalena Musat in the Department of Mathematical Sciences at the University of Copenhagen, which provides a wealth of training and resources on operator algebras and quantum mathematics.


**Keywords:** free probability, information geometry, Wasserstein distance, random matrix, quantum channel
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Commercializing soft wearable systems from a stretchable electronic material' (SoWe) under Horizon 2020.

assistant: **Objectives**

SoWe represents a unique opportunity for the commercialisation of a unique stretchable electronic system that enables the design and manufacturing of large-area, high performance electronic skins. Prof. Lacour and her team, as part of the ERC project ESKIN, build upon a breakthrough innovation - an intrinsically stretchable metallization compatible with standard circuit fabrication and components assembly. These stretchable circuit boards will unlock the form-factor of existing planar and rigid circuitry and contribute to materialize the ""Internet of Things”. SoWe may be integrated and mounted on the human body, robotic surfaces or passive objects.  Our technology enables active surfaces to conform to and improve the perceptive sense of objects, and facilitate network connectivity. Similar to human skin, SoWe will encode sensory information such as contact, applied pressure or movement and transmit the information. Our innovation provides an enormous untapped potential and can transform human - machine interactions. No alternative technology combining design simplicity with high electromechanical performance is available today on the market.In SoWe we aim to 1) establish proof of concept of a new class of stretchable electronic skin, enabled by biphasic solid-liquid thin metallic conductors at industrial scale and to 2) show the potential commercialization purposes. Our stretchable metallization is unique and can be batch fabricated on a wafer scale. To date, all manufacturing processes have been optimized at lab scale.  Moreover, we will show the commercialization purpose by defining the exact business strategy, model and positioning – and partnering with key enablers (business-related and/or technological) for commercial success. During this project, we will gain tec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Emergency ultra-wideband radio for positioning and communications' (EUROPCOM) targeting Sixth Framework.

assistant: **Abstract**

In emergency situations, particularly within smoke-filled partially or completely collapsed large buildings, communications with rescue personnel can be difficult. Safety and co-ordination of the operations is hampered by a lack of knowledge of the location of emergency staff. The project will investigate and demonstrate the use of UltraWideBand (UWB) radio, to allow the precise location of personnel to be displayed in a control centre and simultaneously improve communications reliability. The feasibility of using UWB to search for survivors buried beneath rubble and to generate simple maps will also be investigated.The main intended outcomes of the project are:- Understanding of the overall application requirements and system issues- Development of UWB technology, understanding issues that need to be addressed prior to product development- Interface requirements with existing systems- Performance measurements of a prototype system in a representative environment (Trials and demonstrations)The approach that will be taken is summarised in the following ordered list of top-level work packages:- Requirements definition and prioritisation, involving discussion with the potential users- System design: An iterative process, involving carrying out experiments for the highest risk areas and potentially modifying design concepts as a result. Competing UWB technologies will be assessed and a choice will be made for the prototype.- Prototype build and laboratory testing- Trials: to provide full information on the system performance.In addition, the project will monitor and provide input to, regulatory authorities (in particular the CEPT and ITU).The project will fit with the following (partial extracts from the workprogramme):- To develop open platforms, integrated systems and com
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Middle-Class Migration Aspirations and Social Media's Impact on (Im)mobility'.

assistant: **Concept**

Why do some skilled middle-class individuals from unstable countries leave, while others with similar profiles stay? How does the constant flow of digital information shape migration aspirations? These questions drive the main objectives of MIDSCAPES: (i) to identify migration and stay patterns among Türkiye's middle class, (ii) to explore the role of digital space in spreading migration related information, and (iii) to measure social media's impact on migration aspirations using innovative methods. This project integrates the aspirations-(cap)abilities framework with digital migration studies, enriching both fields by focusing on stay aspirations, social stratification and social media. Focusing on both the sending and receiving ends of migration MIDSCAPES is empirically innovative. The empirical focus on potential and actual migrants from Türkiye to Canada is both timely and relevant. Türkiye serves as a critical case for understanding how middle-class individuals with globally marketable skills respond to structural uncertainties. Canada, a key global destination for highly skilled migrants, is known for its welcoming yet complex selection and admission mechanisms, utilising immigration as a tool for middle-class nation-building. MIDSCAPES embraces a multi-sited and mixed-method approach employing three main data collection methods. 1. in-depth interviews with recent migrants, potential migrants and stayers, 2. digital ethnography, 3. surveys including survey experiments with potential migrants and stayers. These methods are crafted to unpack the complexity of spatial and social mobility aspirations among potential migrants and stayers from middle-class backgrounds. The findings will have implications for key policy and societal challenges: (1) high income countries
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Ion Cyclotron resonance Fourier transform mass Spectrometry', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

The protein expression by itself and the dynamics during disease are at the moment of major biochemical and medical interest. Mass spectrometry is one of the disciplines, which has allowed the study of proteins in that context. The demand for even more sophisticated and more expensive instrumentation such as the Fourier transform Ion cyclotron resonance mass spectrometers (FTICR) has increased due to the ever growing need to study intact proteins and their interactions with other proteins and ligands. Only a handful of such instruments exist in the European union while a larger number exists in the Unites states of America providing the USA with a leading edge in the study of intact proteins by mass spectrometry.An FTICR instrument with the capacity to detect and isotopicaly resolve intact proteins has been recently purchased by the host institute in the Czech republic with funds allocated by the Czech government who immediately recognised the potential and the benefits such analytical capacity will bring. This is the only instrument that has been purchased by any of the new entrants of the European Union and is expected to increase competitiveness of the EU in relation to other major players such as USA and Japan in biochemistry and drug development.The host institute will serve the research and analytical needs of the Czech republic and the neighbouring countries such as Poland, Slovakia and Hungary. Success to the large task undertaken by the Institute of microbiology in the Czech republic on providing regional mass spectrometry expertise can be ensured if technical know-how on the operation of such instrumentation and managerial expertise on operating facilities of that scale is transferred by another institute, which has fulfilled a similar role in another member s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Charge delocalisation and hopping in an ultra-cold atomic lattice' (2002-2006).

assistant: **Innovation**

The overall aim of this proposal is to use the powerful techniques developed for manipulating ground-state atoms, such as optical lattices, to study ultra-cold Rydberg gases and plasmas. More specifically, this proposal uses strontium atoms in a lattice t o look at two different electron transport effects.The first is delocalisation of electrons along the lattice. A Rydberg atom with principal quantum number n=60 has an orbital radius of 280 nm. In an optical lattice, this orbital radius can exceed the distance between atoms in neighbouring sites, and the electronic wavefunctions of atoms trapped at different sites will begin to overlap.It has been suggested that under these circumstances the Rydberg gas may undergo a Mott-type transition to a state where the electrons become delocalised. Ionizing a single site of the optical lattice provides an ideal way to study a second kind of charge transport that is predicted to occur in ultra-cold mixtures of atoms and ions. At such low temperatures, the cross-section for charge-transfer collisions can be high, and the thermal de Broglie wavelength of the atoms and ions, approaches the inter-particle spacing in the gas.Under these conditions, an electron can hop" from a neutral atom onto an ion, and charge transport occurs via the movement of positively charged "holes". This part of the proposal relies on the unique electronic structure of strontium atoms. In combination with techniques developed in quantum information research, this will allow us to control t he electronic state of the gas at the level of a single particle."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Brain-speech tracking in noisy conditions: towards the identification and remediation of dyslexia.' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Dyslexia is a developmental disorder leading to reading difficulties. It affects 5–12 % of children and young adults. Unfortunately, we still lack efficient and cost effective methods to identify and remedy this disorder. Dyslexia appears to be frequently linked to hindered phonological processing at the cortical level, with drastic consequences in the presence of noise. The overarching goal of this project is to better understand cortical speech processing in the presence of noise, in order to provide novel identification and remediation methods for dyslexia.Magnetoencephalography and electroencephalography studies have uncovered the phenomenon of brain-speech tracking, that is, the tracking of continuous speech sounds by cortical activity. This tracking is suggested to reflect speech sound chunking and parsing mechanisms, and is altered in dyslexic readers. Importantly, it can be used to evaluate brain capacity to track a sound stream of interest in the presence of noise.Given that individuals’ capabilities to discriminate speech in noisy conditions improve until age ~12, we propose, as a first step, to characterize brain-speech tracking in the presence of noise 1) across the normal development and 2) in children with dyslexia. To modulate task difficulty, we will use several types of noise (from white noise to babble), with or without visual information of the speaker’s lip movements. We will then attempt to predict subjects’ reading skills based on their brain-speech tracking parameters (i.e. their fingerprint of brain-speech tracking capabilities).Finally, we will evaluate whether neurofeedback sessions can sustainably boost brain-speech tracking. These developments are instrumental to the realization of future studies intended to restore the integrity of brain-spe