RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Thermal and compositional state of the Earth's inner core from seismic free oscillations' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The core, comprising the innermost parts of the Earth, is one of the most dynamic regions of our planet. The inner core is solid, surrounded by a liquid iron alloy. Inner core solidification combined with motions in the fluid outer core drive the geodynamo which generates Earth's magnetic field. Solidification of the inner core also supplies some of the heat that drives mantle convection and subsequently plate tectonics at the surface of the Earth. The thermal and compositional structure of the inner core is thus key to understanding the inner workings of our planet. No direct samples can be taken of the core and our knowledge of the thermal and compositional state of the Earth's outer and inner core relies on seismology. Ray theoretical studies using short period body waves are the most commonly used seismological data; these have led to observations of a large range of anomalous structures in the Earth's inner core, including anistropy, layers and hemispherical variations. However, due to uneven station and earthquake distribution, the robustness and global distribution of these features is still controversial. Long period seismic free oscillations, on the other hand, are able to provide global constraints, but lack of appropriate theory has prevented more complicated structures from being studied using normal modes. Thus, many fundamental questions regarding the thermal history of the core and geodynamo remain unanswered. Here, I propose to develop a comprehensive seismic inner core model, employing fully-coupled normal mode theory for the first time and using data from large earthquakes such as the Sumatra-Andaman event of 26 December 2006. This will dramatically change our current ideas of structure in the inner core. Using a novel combination of fluid dynamics and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Knowledge Yielding Ontologies for Transition-based Organization' to be submitted under Seventh Framework.

assistant: **Abstract**

With the globalization of markets and communication, we are experiencing globalization of problems in the world and of the solutions to these problems. An actual example is global warming and other environmental problems related to rapid growth and economic developments. Globalization of problems and their solutions require that information and communication is supported across a wide range of languages and cultures. This requires a system that can collect distributed information that is structured differently and expressed differently in languages and represent it in a uniform way. It also means that people can access this information in their language and without cultural background knowledge, as experts or laymen. Environmental problems can be acute, requiring immediate support and information available elsewhere. However, knowledge sharing and transitions is also essential for sustainable growth and development on a longer term. In both cases, it is important that distributed information and experience can be re-used on a global scale.<br/>The goal of Kyoto is to develop a content enabling system that provides semantic search and information access to large quantities of distributed multimedia data for both experts and the general public, over a variety of data from wide-spread sources in a range of culturally diverse languages. This is enabled through an ontology linked to wordnets for a variety of languages. Concept extraction and data mining is applied through a chain of semantic processors. The shared ontology guarantees a uniform interpretation for the diverse information from different sources and languages. The system can be maintained by field-specialists using a Wiki platform. Kyoto is a generic system offering knowledge transition across different target g
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Innovation Relay Centre of Slovenia' (SI-IRC-04-08).

assistant: **Innovation**

IRC Slovenia will serve as the competent and reliable national centre for transnational technology transfer (TTT) and the promotion of innovation through support given to their clients. IRC Slovenia possesses a profound knowledge of local companies and t heir technology needs. Its main clientele are SMEs and industry with innovation potential interested in modernising their technological base, and RTD centres interested in exploiting their knowledge. All services needed to support and accomplish TTT, suc h as identifying the technology needs or offers, preparing high quality technology offers and requests, assuring immediate contacts with interested partners and providing assistance with the preparation of supporting agreements and financial schemes, etc ., will be provided, individually tailored to each IRC client. IRC Slovenia will be an active member of the IRC network and ensure wide diffusion of information. In order to accomplish its mission, it will look intensively for synergistic effects with ot her key public and private players in Slovenia that work with companies for their technological modernisation and innovation. Special attention will be given to cooperation with the Regional Innovation Transfer of Technology Strategy of Slovenia (SLORIT TS) team. It will link also with other European networks and organisations dealing with company support. In the period following accession to EU (1st May 2004) IRC Slovenia will also support the proposers of structural and cohesion projects with EU partn ers in TTT. Last, but not least, the IRC Slovenia team will continue its effort for the establishment of a National System of Innovation, especially for the establishment of national funds for TTT.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Modeling International Cooperation Between States' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

A project in Political Philosophy, utilizing Experimental Economics. Aimed at understanding and predicting international cooperation between states, and outlining the conditions under which international cooperation between states is made more and less likely. In order to model states as potential cooperators, we must understand whether and to what extent states possess the agency necessary to cooperative action. The first task of this project will be to investigate the largest group of persons possessing collective agency within the legal / political territory of the state. We generally talk as though the state is something of which we are members; I hope to be able to accommodate our ordinary talk by locating agency in a collective at least roughly similar to what we think of as 'the state'. In the best case, this will be the maximal group of those meeting a certain criterion, for example possessing citizenship or residency, identifying as a national of that state, being regularly engaged in voting and paying taxes. In the worst case, this will be the minimal group of those meeting a more restrictive condition, for example holding an official role within the executive of the state, or occupying the position of Head of State. Once it has been established where exactly agency lies in the group we commonly refer to as 'the state', it will be possible to start thinking about cooperative interactions between such agents, and to start theorizing about states responsibilities in the context of these cooperative interactions, and their members' roles and responsibilities as the constituents of states in these cooperative interactions. This will involve delineating what states' obligations mean for members (citizens, nationals), which is to say, what the 'translation' is betwe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Boosting the Impact of Social Innovation in Europe through Economic Underpinnings' to be submitted under Seventh Framework.

assistant: **Abstract**

SIMPACT advances understanding of social innovation’s economic dimensions, creating new concepts, models and instruments for policy makers, innovators, investors and intermediaries. It systematically investigates how social innovations can enable the most vulnerable in society to become economic assets, integrating critical analysis of current and previous work with future-oriented methodologies, new actionable knowledge and continual stakeholder participation.SIMPACT’s multidisciplinary mixed-method approach advances knowledge and the state of the art by (i) elaborating a theoretical model of the economic dimensions of social innovation throughout its lifecycle; (ii) generating new empirical knowledge on the economic dimensions through rich, theoretically informed analysis of successful and less successful cases; (iii) analysing drivers and barriers shaping the economic impact of social innovations, and levers for their scaling and diffusion; (iv) developing indicators to measure social innovations and tailored methods to evaluate social and economic impact; (v) enhancing modes of public policy production, instruments and guidelines; (vi) generating foresight knowledge through agent-based modelling and scenario building.SIMPACT integrates theoretical, empirical and actionable knowledge to create evidence-based approaches to business development, public policy and research. A participatory research approach actively engages policy makers, innovators, investors and intermediaries of vulnerable groups. Action learning, indicator labs and stakeholder experiments facilitate processes of co-creation, stimulating shared learning, strengthening practitioner knowledge and enhancing conceptualisation of the economic base. Partners' understanding of welfare regime diversity, incl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Novel Drug Therapy with Potential to Cure Neuro-Degenerative Diseases' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Over 10M Europeans suffer from neurodegenerative diseases such as Alzheimer’s Disease (AD), Parkinson’s Disease (PD) and Amyotrophic Lateral Sclerosis (ALS). Whilst there are many drugs that treat symptoms of these diseases, there are no therapies that can reverse or cure them.Our novel compound NeuroProtect has the potential to be a game changer by healing damaged neurons. NeuroProtect is a natural herb-derived compound with remarkable neuroprotective, neuro-rescuing, anti-apoptotic, and axon-outgrowth effects in mouse primary neuronal and human neuronal models. We have proven the compound’s efficiency in preliminary in-vitro tests. To take NeuroProtect to market fastest, we will focus on ALS that where we can use the orphan drug route and get clinical approval faster. This gives us an immediate target market of €300M per year in Europe, the US, Japan and Switzerland alone. Although ALS is relatively rare, the socioeconomic significance of the disease is extensive:  a recent study showed that total lifetime costs for ALS were €1.15M per patient. NeuroProtect can therefore contribute to reduce the global economic burden of ALS. We are planning to take the standard route for commercialization in pharma industry: take the compound through pre-clinical studies, Phase I and Phase II clinical trials and then outlicense to a large pharma company who will refund our cost until they finish the Phase III trials and then pay us royalties.  Our team is led by two experienced co-founders: Dr. Yuhong Dong, who has worked for a multinational pharmaceutical company for over 10 years as well as a physician for 4 years, and David Guan, who has over 10 years of management positions at multinational companies (HP, Honeywell). We are also supported by experienced advisors and investors to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Biomarker for Cardiovascular Risk Assessment in Europe' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Biomarkers are considered as tools to enhance cardiovascular risk estimation. However, the value of biomarkers on risk estimation beyond European risk scores, their comparative impact among different European regions and their role in the drive towards personalised medicine remains uncertain.Based on harmonised and standardised European population cohorts we have built significant research collaboration, expertise and infrastructure in the EU. We will apply highly innovative SME-driven technologies and perform large-scale biomarker determination to assess the predictive value of existing and emerging biomarkers.Selection of emerging biomarkers will be based on integrated cutting-edge quantitative proteomic, transcriptomic, metabolomic, and miRNomic datasets established by private and public consortium members that will be disclosed to this consortium. Existing biomarkers will be selected based on non-redundancy and their association with cardiovascular risk and phenotypes. After SME-guided development of innovative assay systems biomarkers will be tested and validated in a stepwise fashion among European populations in primary and secondary prevention. In addition to their impact on risk prediction, their association with lifestyle determinants and cardiovascular phenotypes assessed by ultrasound and MRI technique will be evaluated.We will establish a BiomarCaRE panel which leads to improved disease prediction among different European populations. International collaborations with world-class clinical trial investigators will add data on the interaction of the BiomarCaRE panel with risk-lowering medication and lifestyle changes. The outcome of SME-driven technology development and clinical validation will undergo a medical technology assessment. The determination of cos
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Diagnostic and epidemiological markers for tracking of endemic and resurgent european leishmaniasis' (1998-2002).

assistant: **Concept**

Visceral leishmaniasis is one of the most important vector-borne zoonosis in Southern Europe and lacks reliable, rapid, simple and sensitive typing methods. The current reference typing method, allozyme electrophoresis, is demanding and has low-resolution power for genetic diversity and species taxonomy. We propose to develop new alternative molecular typing methods, based on clade-specific markers determined through DNA-based phylogenetic reconstructions. Phylogenies will be built from DNA sequences of genomic loci exhibiting a range of genetic variation from conserved to highly variable (microsatellites), and will be compared with allozyme-based phylogenies. Molecular typing procedures will be designed to fill the above-mentioned typing requirements. Applicability of the new markers will be evaluated for clinical typing of endemic and imported human and canine infections and for pilot studies of sympatric and allopatric populations, therefore addressing fundamental epidemiological and clinical questions. An electronic database for Leishmania typing data and strain information will be generated, and will be available through the Internet.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Real-time study of pattern formation dynamics  in nonvariant eutectic solidification microstructures' in the context of a Seventh Framework call.

assistant: **Objectives**

The present proposal concerns a multidisciplinary experimental research program in the field of solidification science with various impacts in nonlinear physics, metallurgy, materials science, and engineering. The problem studied is the formation dynamics of multiphase microstructures in eutectics, which are naturally grown composites that are generally solidification-processed. These microstructures basically consist of nearly periodic arrangements of different crystal phases on the micrometer scale. Because of their low and constant melting temperatures, and the remarkable mechanical, optical, and electrical properties that they owe to their fine microstructures, eutectics are extensively used in metallurgical industries including casting and soldering. However, a substantial challenge for eutectic materials is to control the variability of the microstructure on a scale larger than a few tens of a micrometer. If the microstructures were perfectly periodic on a macroscopic scale, the solid would present extraordinary properties. However, for as yet unknown reasons, eutectic microstructures always exhibit a large density of “defects”, which destroy the long-range periodicity and reduce the quality of the material.This proposal addresses this problem using real-time experiments and numerical simulations to examine the formation dynamics of Nonvariant EUtectic SOLidification (NEUSOL) microstructures with an emphasis on dynamics of three-phased eutectic patterns and anisotropy effects.Control of the microstructure is essential to obtain a homogeneous structure, which is needed to yield consistent properties and reproducible materials. This project will provide a clear improvement of our fundamental understanding of solidification pattern formation in ternary eutectics and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Foundations for Software Evolution' to be submitted under Seventh Framework.

assistant: **Abstract**

Software evolution refers to changes made to a software system after its deployment. These changes may be caused by changing requirements, domain assumptions, or computing infrastructure, and may affect the system’s implementation, architecture and/or requirements. Evolution may be automatic (aka self-adaptation), or manual, or something in-between. This project aims to develop principles that underlie, and concepts, tools and techniques that support evolution. The project will focus on software-intensive systems. Such systems consist of software, human and organizational elements that work together to fulfill organizational and human objectives. Our proposed research is founded on ideas and research results from Requirements Engineering (RE). Evolution is to be supported by design-time models that are made available at run-time. These models capture system requirements and domain assumptions, augmented with design and implementation details. When evolution is automatic, supported by monitor-diagnose-compensate-execute feedback loops, these models determine (i) what is to be monitored, (ii) whether the system is operating according to its intended purpose, (iii) what are possible compensations for deviations from intended behaviour, (iv) how to evolve the system. When evolution is manual, these models support evolution activities, carried out by humans, by offering a comprehensive picture of the requirements and assumptions under which the system operates, along with traceability links between elements of these models and code. This means that design-time models need to capture stakeholder intentions and commitments, social interactions, business processes, and organizational goals that ultimately determine system requirements. Expected results from the project include