RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Haptic, Audio and Visual Interfaces for Maps and Location-Based Services' (HaptiMap), addressing dissemination and exploitation.

assistant: **Impact**

The HAPTIMAP project will deeply embed accessibility into digital mainstream maps and mobile location-based services. Our strategy is twofold: firstly to develop tools that make it easier for developers to add adaptable multimodal components (designed to improve accessibility) to their applications; and secondly, to raise the awareness of these issues via new guidelines and to suggest extensions to existing design practices so that accessibility issues are considered throughout the design process.<br/>The concrete outcomes of the project will be an open, interoperable and standardized adaptable toolkit together with a set of design guidelines that help developers of mainstream applications make maps in general more accessible and easier to use (not only for disabled users but for everyone). We will raise the industrial awareness of accessibility issues by arranging workshops and also by providing an educational module targeted at engineering and design students. Furthermore we will develop design methods and tools that support existing development practices so that it becomes easier to embed 'accessibility' into the design process, making it an integral part of the work instead of being added afterwards as is currently often the case (if the issue is addressed at all). Finally, example applications that illustrate the use of the toolkit and guidelines will be developed and will be evaluated and demonstrated in multiple real life scenarios<br/>In this project we have chosen to focus on digital maps and location based services, since these are  strongly emerging  information services used for a wide range of PC and mobile applications. Our results will be generally applicable, but we have selected this application area as a way of providing our project with a concrete cor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Applied Public-Private Research enabling OsteoArthritis Clinical Headway' (APPROACH) under Seventh Framework.

assistant: **Objectives**

The problem: finding the right patient for the right treatmentDespite a large and growing disease burden in osteoarthritis (OA), many pharmaceutical companies have de-emphasized or even abandoned OA drug development due to perceived hurdles. Crucial in this is the lack of appropriate outcome measures that can robustly identify patient benefit from a specific therapy. The lack of specific and sensitive endpoints to differentiate between responders and non-responders both at the level of pain and tissue structure modification (disease modifying OA drug: DMOAD) has led to trials that included hundreds of patients in each arm with at least 3-years follow-up. Even despite these enormous trials, EMA and FDA have not approved any DMOAD yet. There is a general lack of understanding OA pathogenesis, which appears rather variable and likely reflecting different phenotypes with fundamental differences in disease aetiology, tissue alterations, clinical manifestations (pain/mobility) and disease progression. Although the current mind-set for drug treatment in the field is moving to a more personalized medicine and patient stratification approach, there are no accepted methods or guidelines to classify patients according to their prognosis and differentiate between subsets in terms of diagnosis methodology and treatment plan. The APPROACH consortium brings together a competent and multidisciplinary group of stakeholders that will setup – for the first time – a longitudinal cohort based on highly innovative stratification methods that identifies different OA phenotypes and subsequently develop guidelines for differentially diagnosing the right patient for the right treatment.The stratified medicine APPROACH The APPROACH consortium brings together a unique complimentary set of skills t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'European network to promote research into uncommon cancers in adults and children: Pathology, Biology and Genetics of Bone Tumours' (EUROBONET) targeting Sixth Framework.

assistant: **Abstract**

Primary bone tumours are rare, accounting ~0.2% of the cancer burden. Children and young adolescents are frequently affected. Their aggressiveness has major impact on morbidity and mortality. Though progress has been made in pathological and genetic typing, the aetiology is largely unknown. Though advances in therapeutic approaches increased survival, significant numbers of patients (~40%) still die. Within the EuroBoNeT integration will be achieved by staff exchange and website-based discussion forums to increase and disseminate knowledge of primary bone tumours at the molecular level for development of new tools for patient care and cure and technology. With this integration exchange of material (virtual BioBank), Standard Operating Protocols and the use of technology platforms will enable us to obtain statistical significant datasets, otherwise not achievable due to the rareness and large number of sub entities.A joint programme will contribute in obtaining molecular portraits of tumours, separated in 4 research lines (RL). In each RL the biology of the separate group (RL1: cartilaginous tumours; RL2: osteogenic tumours and related sarcomas; RL3: osteoclastogenesis and Giant cell tumours of bone; and RL4: Ewing family of tumours) will be examined by genome wide expression and genomic aberration studies. More specific hypothesis driven approaches will be investigated by RNA/protein expression and mutation analysis. Knowledge on normal growth and differentiation will be gathered through in vitro studies.This would lead to further understanding and identification of markers for malignant transformation and/or progression, as well as identification of therapeutic targets. Next to research, dissemination of knowledge will be achieved by training courses on bon e and soft
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Green Active Management of Energy in IT Service centres' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The vision of the GAMES project is for a new generation of energy efficient IT Service Centres. With the unprecedented digitisation of business and government processes across Europe, energy efficiency of IT Systems and IT Service Centres is dramatically emerging as one of the most critical environmental challenges to be dealt with. A first yet partial answer to the energy challenges is offered by the emerging IT Service Centre  paradigm, in which the available computing resources are shared by several different users. However, current tools and methods for assessing and managing energy efficiency at the IT Service Centre level were designed to operate in isolation, not taking into account all the interrelations between the different layers (business/applications, infrastructure, facility) and the effect of these interrelations on energy consumption. The GAMES project aims at developing a set of innovative methodologies and Open Source ICT tools for designing and managing energy efficiency in IT Service Centres, by combining all the three above layers. This will be done by: 1) delivering a methodology and a web toolset for the holistic design of green IT service centres, trading-off Quality of Service, performance, virtual and physical resource allocation and overall energy efficiency, 2) enriching the GAMES toolset by implementing advanced algorithms for closely aligning applications' demands for power with the resource availability, and combining these algorithms with data mining technologies; 3) complementing these tools and methodology with a run-time environment for integrated sensing, monitoring and adaptive control, capable of assessing in real time to a what extent the implemented course of actions will improve energy efficiency. The main expected outcome will b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Dual citizenship, governance and education: a challenge to the European nation-state', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

The aim of this project is to clarify, analyse and compare policies and their implementation in the area of citizenship, especially dual citizenship, in Estonia, Finland, France, Germany, Greece, Israel, Portugal, and the United Kingdom. In each participating country, four methodologically identical studies will be conducted focusing on regulations, prevailing practices and the conceptions and experiences of policy-makers, authorities and individual citizens in relation to dual citizenship and its political and educational implications. These studies make use of both quantitative and qualitative research methods. As a result, we will provide a comparative analysis of the ways in which dual citizenship operates in Europe and a set of recommendations for national and international policy-makers, authorities and educators.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Systemic signalling in plant – aphid interactions' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

While the effects of aphid feeding on leaves are well documented, the influence that the presence of aphids has on distant leaves that are not directly subject to attack is poorly documented and associated systemic signalling pathways are not understood. This proposal therefore seeks to characterize systemic signalling pathways that are specific to aphid feeding in Arabidopsis thaliana and potato to determine how they alter aphid fecundity. Local and systemic responses in gene transcription will be compared, with specific focus on reduction-oxidation (redox) signalling networks and responses. Arabidopsis mutants with defects in the accumulation of the antioxidant, vitamin C and in the production of reactive oxygen species (ROS) and redox processes, which have alterations in defence to pathogens will be characterized to assess the roles of antioxidants and antioxidants in the plant – aphid interaction. Potato (Solanum tuberosum) is the third most important food crop in the world but the value of the crop can be greatly decreased as a result of aphid-borne viruses.The aim of the fellowship is to reorient the career path of an experienced researcher in order to broaden her career prospects in line with the needs of the future knowledge-based bio-economy of Europe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Pulmonary hypertension: “aberrant” mimicry of lung vascular morphogenesis?' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

Chronic pulmonary hypertension (PH) is a lethal disease characterized by the accumulation of persistently activated cell types in the pulmonary vasculature, exhibiting aberrant expression of genes driving apoptosis resistance, proliferation, inflammation and matrix remodeling. Current vasodilatory therapies for PH do not normalize these activated phenotypes. I have performed an “integromics” approach – combining epigenetic and transcriptional analyses to comprehensively elucidate the underlying molecular mechanisms. This approach provided evidence for the recapitulation of a “fetal-like” “remodeled” lung vascular phenotype, orchestrated via central lung developmental transcription factor (TF) networks with particular emphasis on TBX4, TBX5 and SOX9. Moreover, in addition to de-novo onset of this “fetal epigenetic programming” in adult PH, postnatal maintenance of such programming may underlie persistent pulmonary hypertension of the newborn (PPHN). Placing TBX4/TBX5/SOX9 at the center, I will probe this hypothesis i.e. will define their contribution to vascular remodeling processes underlying neonatal and adult PH. Studies will be performed in primary vascular cells and viable tissue slices from human/ experimental PH lungs, and various transgenic mouse lines. Furthermore, I will address the relationship among TBX4/TBX5/SOX9 in a transcription network that controls PH development using CRISPR–dCas9-activator mice. In addition, uncovering the TBX4/TBX5/SOX9-epigenetic circuitry by profiling epigenetic landscape ([sc]RNA-, ChIP-, ATAC-, MeD-, histone PTMs- seq) in both “pathological remodeling” and the loss of “physiological reverse remodeling” in PPHN, I aim to harness novel intervention strategies (locus-specific epigenetic modifications) to reverse aberrant remodeling
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Performance Portability of OpenMP', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

In the last years, the industry is adopting OpenMP as a common shared-memory programming standard. Using this standard eases the task of implementing parallel programs for SMPs and makes parallelism more popular in industrial environments. On the other hand, complete OpenMP is currently only available for SMP machines, but no efficient implementation exists for other architectures. Our objective is to build an environment able to generate efficient OpenMP code for any architecture, which will avoid the necessity of using different programming models for different architectures. These architectures will range from shared-memory architectures and multi-threaded architectures to clusters of workstations/SMPs with software distributed shared memory (SDSM). In the last years, the industry is adopting OpenMP as a common shared-memory programming standard. Using this standard eases the task of implementing parallel programs for SMPs and makes parallelism more popular in industrial environments. On the other hand, complete OpenMP is currently only available for SMP machines, but no efficient implementation exists for other architectures. Our objective is to build an environment able to generate efficient OpenMP code for any architecture, which will avoid the necessity of using different programming models for different architectures. These architectures will range from shared-memory architectures and multi-threaded architectures to clusters of workstations/SMPs with software distributed shared memory (SDSM).OBJECTIVES- Design an environment able to generate portable and efficient OpenMP code for any parallel/distributed architecture focusing the following issues:A) Extension of OpenMP:1. Extend OpenMP expressiveness to exploit parallelism in irregular task graphs;2. Improve wor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'The nonlinear high energy regime of Quantum Chromodynamics', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

This proposal concentrates on Quantum Chromodynamics (QCD) in its least well  understood ""final frontier"": the high energy limit. The aim is to treat the formation of quark gluon plasma in relativistic nuclear collisions together with other high energy processes in a consistent QCD framework.  This project is topical now in order to fully understand the results from the maturing LHC heavy ion program. The high energy regime is characterized by a high density of gluons, whose nonlinear interactions are beyond the reach of simple perturbative calculations. High energy particles also propagate nearly on the light cone, unaccessible to Euclidean lattice calculations. The nonlinear interactions at high density lead to the phenomenon of gluon saturation. The emergence of the ""saturation scale"", a semihard typical transverse momentum, enables a weak coupling expansion around a nonperturbatively large color field. This project aims to make progress both in collider phenomenology and in more conceptual aspects of nonabelian gauge field dynamics at high energy density:1. Significant advances towards higher order accuracy will be made in cross section calculations for processes where a dilute probe collides with the strong color field of a high energy nucleus. 2. The quantum fluctuations around the strong color fields in the initial stages of a relativistic heavy ion collision will be analyzed with a new numerical method based on an explicit linearization of the equations of motion, maintaining a well defined weak coupling limit.3. Initial conditions for fluid dynamical descriptions of the quark gluon plasma phase in heavy ion collisions will be obtained from a constrained QCD calculation.We propose to achieve these goals with modern analytical and numerical methods, on which
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Bio-based surfactants from renewable waste streams for the circular economy' in the context of a Horizon Europe call.

assistant: **Objectives**

With climate and environmental concerns topping the global agenda, industries across all sectors are under tremendous pressure to rapidly change their existing fossil-based practices by shifting toward cleaner, greener, more sustainable (in one word: future fit) solutions in business and production, while maintaining economic competitiveness internationally. Surfactants (17 million t/year market globally) are omnipresent in key industrial segments (detergents, personal care, coatings, agrochemicals, pharmaceuticals) and companies are actively looking to shift toward bio-based alternatives while maintaining product performance. Surprisingly, the valorization of renewable waste streams occurring in large quantities for making novel surfactants has not been adequately exploited so far. The reason for this is the lack of fundamentally new technologies in this area.With the credo: Superior performance and clean conscience, PureSurf introduces ground-breaking manufacturing concepts to produce novel high-performance bio-based surfactants from currently underutilized renewable waste streams. In ERC PoC PURE project, novel green surfactants were obtained by green and scalable synthetic pathways, resulting in 2 patent applications. Building on this, the PureSurf validation activities will include: -Upscale at least one gemini anionic and one zwitterionic surfactant structures to 1 kg to validate their properties, using clean starting materials-Upscale (to 5 kg, TRL5-6) at least one selected example using industrial waste streams-Determine properties, ecotoxicity, biodegradability (also anaerobic) as well as performance in industrial applications-Critically compare to existing surfactants, establish a business case and prepare an investor ready technology.The PureSurf team, consis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'INTEGRATED ENERGY SYSTEM - A PATHWAY FOR EUROPE' (IntEnSys4EU) targeting Horizon 2020.

assistant: **Abstract**

INTENSYS4EU aims at addressing the SET-Plan identified novel interacting integration challenges, where- the consumer becomes active and is put at the center of the energy system,- a demand focus that increases energy efficiency across the energy system,- an energy system optimization leading to a secure, cost-effective, clean and competitive energy supply.Energy networks are critical to successfully address the above integration challenges. The project managed by four independent players (ZABALA Innovation Consulting (coordinator), TECHNOFI, RSE and BACHER Energie) involves the technical expertise of the members of four associations (ENTSO-E, EDSO, EASE and EERA) to implement parallel processes in view of defining and implementing a novel approach to the subsequent RD&I strategy for energy networks.The INTENSYS4EU project objectives are :-To provide strategic guidance about the R&I activities (low to high TRL, priorities) raised by the integration issues of the electricity system into the wider European energy system-To interact with the stakeholders of the ETIP  SNET (European Technology and Innovation Platform Smart Networks for Energy Transition) at European level as well as the ETIP stakeholders at national and international level.- Setting several long term energy scenarios at European level- Analyzing the on-going research, development and innovation projects in the EU and, when relevant at Member State levels- Enhancing collaboration between projects through a support to the on-going BRIDGE process initiated by the European Commission for the funded R&I projects of Horizon 2020- Maximizing cross border knowledge sharing about energy system optimization through interaction with national level players- Supporting in fine-tuning the development of an upgraded draft