RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Strong light-matter coupled ultra-fast and non-linear quantum semiconductor devices'.

assistant: **Objectives**

This project will combine for the first time strong light-matter coupling in quantum-confined electronic systems with the optical and electronic non-linearities of semiconductor heterostructures: we will develop device concepts with unique ultra-fast, non-linear and quantum functionalities. The key ingredient is an unconventional use of the strong light-matter coupling regime (SCR), a fascinating concept that is recently transitioning from basic physics to quantum devices.We will first address fundamental physics problems, then well turn to device applications. A key conceptual building block is that the nature of optical non-linearities is radically modified when operating in the SCR. This has profound consequences. We will study few-photon non-linearities, in particular the ultimate case of devices that can sense virtual photons. This will lead us to device concepts whose behavior is enabled by vacuum-field photons, bringing us radically beyond the state of art.  We will then move to the case of many photons. We will focus on absorption saturation, that explored only in the weak coupling regime, where it is difficult to engineer. We have discovered that in the SCR instead it becomes tailorable and previously unavailable functionalities can be envisioned. This has profound consequences: we will demonstrate semiconductor saturable absorber mirrors (SESAM) for the mid-IR spectral range, a technology that revolutionized ultra-fast lasers in the near-IR, but is missing at longer wavelengths. We will apply them to fiber and interband cascade lasers, radically advancing the potential of those sources. These are ground-breaking demonstrations for mid-IR science and technology. SMART-QDEV is a project rooted in fundamental physics research, able to open up new horizons and res
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Proteome-wide Functional Interrogation and Modulation of Gut Microbiome Species' in the context of a Horizon Europe call.

assistant: **Objectives**

The gut microbiome plays a key role in human health. Genomics approaches excel at cataloguing species composition, and associating imbalances with disease. Yet, as we are oblivious to the function of a large proportion of proteins of these organisms, we are limited in our understanding of the molecular mechanisms that drive disease or promote health. In this groundbreaking project we will systematically identify the function and interactions of proteins of microbiome species, deliver compounds to modulate them, and develop strategies to rationally manipulate microbiome composition.We will use a scalable systems biology approach based on high-throughput proteomics, using more than 100 drugs to perturb the proteome of a panel of 38 prevalent and phylogenetically diverse bacterial species that colonize the human gut. Proteins involved in the same biological process have coordinated changes in their levels across perturbations, allowing us to infer function based on annotated proteins. We will further assess which proteins are likely to physically interact as they co-aggregate upon heat-induced denaturation, leading to a map of the functional protein network of these species. We will then identify the mechanisms of action and resistance of the used drugs by using thermal proteome profiling, and by measuring intracellular drug concentrations. This will allow us to identify species that encode the target, but no resistance elements, so we can use the information to specifically deplete disease-associated species from microbial communities. These strategies extend beyond the strains studied in this project, as homologs of these proteins can be identified solely from genome sequences.Overall, this project paves the way for the microbiome field to move from associations to targe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Development of new Non-Toxic Methodology for the Synthesis of Important Pharmaceuticals Using Free Radicals' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

Research objectives and contentThe application of the vast array of excellent synthetic procedures using triorganotin hydrides to pharmaceutical synthesis is precluded by the toxicity of organ tin. An increasing number of synthetic processes in thepharmaceutical industry use tributyltin hydride because the alternative methodology is lengthy, time consuming and costly. In these syntheses the removal of the toxic organotin residues to required non-toxic levels is also costly and time consuming. The essence of our project is to replace triorganotin hydrides with their non-toxic I germanium analogues for industrial generation of free-radicals in chain reactions. These germanium hydrides have similar reactivity to the corresponding tin hydrides and cantherefore act as substitutes in radical reactions. This will allow exploitation of the vast array of synthetic procedures, which require triorganotin hydrides as the free-radical generating reagent. New synthetic methods will be developed for the economic synthesis of the required triorganogermanium hydrides using the relatively cheap germanium oxide as the starting material.The objectives of the project are:- Development of the catalytic application of triorganogermanes for generation of free radicals.- Synthesis of novel pharmaceuticals to test the methodology.Training content (objective, benefit and expected impact)Dr Bowman's research group is internationally known for free radical research and provides an excellent environment for furthering research training in radical chemistry and synthetic methodology related to pharmaceuticals to further the biological chemistry background of Dr Alcaraz.Expected impact and benefit: We already have considerable industrial interest in the planned methodology and it will provide a facile
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Training System on New Safety Technologies for Road Transport Addressed to Professional Bodies of the Automotive Sector' (SAFETY-TECHNOPRO) targeting Sixth Framework.

assistant: **Abstract**

A general objective of the eSafety initiative is to build up a European strategy for accelerating the research and development, and the deployment of existing and new road transport safety technologies. In the Specific Support Action SAFETY-TECHNOPRO, the definition and development of a Training System addressed to professional bodies of the automotive sector is conceived to achieve maximum acceptance and awareness on road transport new safety technologies by the end users.The project partners are: CENTRO ZARAGOZA, IDIADA AUTOMOTIVE TECHNOLOGY, REAL AUTOMOVIL CLUB DE CATALUÑA, UNIVERSITY OF MAGDEBURG, and DEKRA.The addressed professional collectives involved are: Sales persons working in dealerships, Repairing personnel working in garages and Vehicle inspectors working in technical vehicle inspection workshops.These professional bodies are represented in the project by the international organisation DEKRA, through DEKRA QUALIFICATION GMBH.It is essential to know and analyse the opinions, habits and perceptions of the users (both end users and professionals) gathering information directly from them through an Internet tool used in the frame of EuroTEST, managed by associated members to FIA, throughout 12 European countries (Belgium, United Kingdom, Spain, Netherlands, Germany, Italy, France, Portugal, Finland, Croatia, Norway and Slovenia).The most important technical work is the definition and elaboration of the training system prototype, constituted by 6 modules adapted to the specific professional bodies, and also characterised by a technological updating module, that will allow integrate on-line the most recently commercialised safety technologies. The prototype will be tested in 400 workshops and dealerships.The project results diffusion will be based on a European
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Smart and flexible heat and power from biomass derived liquids for small-scale CHP application' to be submitted under Horizon 2020.

assistant: **Abstract**

The objective of SmartCHP is the realization of a cost-effective and flexible energy system by using a liquid bio-energy carrier to fuel an efficient diesel-engine based CHP. It will develop a smart and flexible, small-scale CHP unit (100-1,000 kWe) fueled with fast pyrolysis bio-oil originating from different types of biomasses and/or residues. Fast pyrolysis converts biomass into a uniform liquid intermediate called FPBO, and the process is characterized by a high feedstock flexibility. Nowadays, FPBO is produced on commercial scale in Europe. For small scale biomass CHP systems a standardized fuel, enabling optimization of the conversion units and thus creating a cost competitive value chain, is highly preferred. Moreover, to achieve high resource efficiencies at all times a highly flexible ratio between heat and power generation is desired. A smart, demand driven unit should be capable of dealing with the fluctuating energy demand and/or varying availability of wind/solar power. The SmartCHP system combines a FPBO fueled engine and flue gas boiler to produce electricity and heat at a high efficiency over the whole load range. A dedicated flue gas treatment guarantees low emissions. Moreover, a wide, adjustable heat-to-power ratio is covered which enables to respond directly to actual energy demands. The final result of SmartCHP is an integrated system consisting of an engine, boiler and flue gas treatment system adapted and optimized to run on FPBO (TRL 5). A real-time, predictive, dynamic model will be developed to find the optimal operation point at all energy demands. Techno-economic, socio-economic and environmental assessments will be performed to identify real market opportunities. The SmartCHP unit will be based on standard diesel engines, and specific invest
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Influence of biological and physical processes on intertidal sediment dynamics and on the release of pollutants trapped in sediments and the toxicity of these pollutants' (BIO-ENGINEERS).

assistant: **Innovation**

Estuaries and coasts in the SW of England contain historically contaminated sediments. These contaminants include heavy metals Paths and organic compounds. They accumulate in the sediment, which can then act as a contamination source. Bottom-dwelling organisms, like shellfish, can accumulate these chemicals making them a potential risk to human health when consumed. Several processes can lead to pollutant release into the water column: diffusion, physical processes (climate change - tidal currents, storms & rainfall) and biological processes (perturbation). The aim of this multidisciplinary project is to improve understanding of biological and physical processes influencing sediment readability and pollutant mobilisation. We will focus on the impact of various biotas as bio-engineers and their influence on sediment dynamics, the release of pollutant trapped in sediments and the toxicity of these pollutants. There is no similar study devoted to the interactions between chemical, biological and physical processes. This subject is a new approach coupling physical and biological processes to gain insights into the combined actions, which influence sediment stability, readability and deposition in estuaries and finally pollutant fluxes. The research project includes both field and laboratory studies. It is based on several novel methods and techniques presently available at Plymouth Marine Laboratory (host institution) or developed and used by the researcher at the Marine Biological Station in Aeration (France): microcosms, annular flumes, micro-acoustic Doppler velocipede, fluorescent particulate tracers, pollutant analyses, sensitive measurements of sub lethal stress. This proposal is submitted jointly by Professor John Widows from the Plymouth Marine Laboratory and by the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Precipitate Elastic Stress States', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

I am a Professor in the Department of Physics at the University of Oslo, and I am currently 1 of 6 full time professors at the Norwegian Research Centre of Excellence on the Physics of Geological Processes (PGP), where I am responsible for all its experimental activities. Although there is a wide range of expertise in PGP, there are still limitations to our knowledge, tools and research techniques which must be overcome. The Grenoble complex, where very strong university research teams work alongside leading CNRS laboratories, has most of the capabilities that we lack. I propose to launch an original research project that probes fundamental questions in Gibbs' thermodynamics and is interdisciplinary in it's application to Physics, Earth Science and Materials Science. Recent experimental results from my group contradict theoretical results from the group of Chaouqi Misbah (of Laboratoire de Spectrometrie Physique (LSP) of the University of Joseph Fourier (UJF) in Grenoble) and afford an original and innovative angle on 140 years of theoretical discussions on the thermodynamic theory of non-hydrostatically stressed solids. I propose a 12 month integrated theoretical and experimental project in Grenoble which will use state of the art continuum modeling techniques and high resolution optical and synchrotron X-ray techniques to test 5 bold hypotheses. The goal of the proposed project will be to combine the theoretical and experimental excellence in the Grenoble region with the unique physics/geoscience research at PGP in order to 1) publish two original research papers in top rated physics and geoscience journals, 2) train me in state of the art continuum mechanics modeling methods and high resolution optical and sychrotron X-ray methods, 3) enhance my ability to mange rese
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Analyzing and Preventiving Extremism Via Participation' to be submitted under Horizon 2020.

assistant: **Abstract**

Main PurposeThe project primary purpose is to prevent extremism, radicalisation and polarisation that can lead to violence through more effective social and education policies and interventions that target at risk groups to be performed through the establishment of a holistic framework and the engagement\involvment of  social actors, local communities, civil society, and policymakers.Objectives and expected impact- to develop an holistic multidimensional model based on a participatory fieldwork and a mixed method approach,- analysing and discussing through an action research strategy involving young people in different side of Europe, the socio psychologic mechanisms that lead to extremism, radicalisation and polarisation,- to identify future perspectives and trends of hate speech, extremism and radicalisation,- developing communicative tools, education approaches and community-based strategies,- to improve the awareness of young people and communities as well as the society at whole,- to realize databases and a systematic set of indexes and early-warnings,- developing a set of policies recommendations with the participation of stakeholders, policy-makers and targets,MethodologiesPARTICIPATION project starts to the assumption that broken a top-down approach in research and in preventive design is needed. In fact, an holistic approach leads to consider vulnerable people as protagonists of the research processes and as producers of knowledge on themselves, included the way and the strategies for preventing extremism and radicalisation. So, if a mixed method approach that combine qualitative and quantitative data is a fundamental methodological way in order to catch all the complexity of processes at micro, meso and macro levels, it will be linked to an action research app
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The Evolution of Competition and Cooperation: how polymorphisms in microbial populations optimise virulence and mediate drug resistance' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Microbes form intricate communities where multiple strains and species communicate cooperate and compete, they can cause life-threatening diseases and destroy our food sources. Metabolism is key to these interactions, yet the way microbes acquire and utilise nutrients is often overlooked in evolutionary studies of pathogenicity, virulence and antibiotic resistance. I will address this by quantifying how microbial community composition is determined by the metabolism, genetics and physiology of individual players, establishing principles by which microbial composition affects virulence and antimicrobial resistance. Competition for resources is the most basic of ecological interactions, fundamental because one cell directly impacts the fitness of others. It is only by incorporating nutrient acquisition and utilisation into studies of virulence and antibiotic resistance that we can predict, and ultimately control, the evolutionary response of microbes to resource stresses, antimicrobials and host defences. I will address two outstanding problems:Challenge one: Pathogens must acquire nutrients from their hosts, but what combination of different resource acquisition and utilisation strategies maximise population success and, therefore, virulence?Challenge two: Antibiotics can perturb the composition of polymicrobial communities from susceptible to resistant species but how is this shift mediated by resource utilisation strategies?Fully integrating empirical data and theory, concepts from ecology and evolutionary dynamics will be key. We will formulate new theoretical tools that allow us to make predictions that will be fully challenged by data, both in vitro and in vivo.  This research will exploit advances in the molecular genetics of important plant and human pathogens and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Mechanisms underlying lateral polarity establishment in plant cells' in the context of a Seventh Framework call.

assistant: **Objectives**

Higher plants and animals establish elaborate body plans with one end of the organism being different from another. Polar organisation is also of fundamental importance at the single-cell level, because mutations affecting cell polarity may cause severe body deformations. Hence, cell polarity is a central theme of biological research and much progress has been made towards our understanding of cellular polarisation along the shoot-root (apical-basal) axis of plants. By contrast, how polarity is established towards inner and outer lateral membranes of plant cells remains unresolved. Here, I propose to identify components controlling lateral cell polarity, employing the root epidermis of the genetic model plant Arabidopsis as an excellent system readily accessible for cell biological analyses. Root epidermal cells display polar nuclear movement towards the inner lateral membrane and proteins located at the outer lateral membrane. We will employ tools for visualization of these polar events that will enable us to A) perform forward genetic screens to discover signals and requirements for polar nuclear movement and outer lateral membrane polarity, B) apply forward and reverse genetics to unravel cytoskeletal requirements of lateral polarisation, C) employ live-cell imaging to reveal the dynamics of polarising events and D) combine genetic and cellular analyses with regulators of apical-basal polarity. Our work will uncover how a single cell separates and integrates polarising events along diverse axes. The proposed research is groundbreaking, as it will lay foundations for an understanding of lateral polarity establishment in plants. Finally, it will aid our understanding of how mechanisms underlying polarising events evolved differently in diverse multicellular organisms.