RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Improved Methods for the Assessment of the Generic Impact of Noise in the Environment' under Sixth Framework.

assistant: **Concept**

For the production of strategic noise maps as required under the EU Directive 2002/49/EC, improved assessment methods for environmental noise will be required. Noise from any major source, be it major roads, railways, airports or industrial activities in agglomerations, needs to be included in the noise mapping. For road and rail, improved methods will be developed in the 5th framework Harmonise project. These methods will be adopted to develop methods for aircraft and industrial noise in the IMAGINE project proposed here. Noise source databases to be developed in IMAGINE for road and rail sources will allow a quick and easy implementation of the methods in all member states. Measured noise levels can add to the quality of noise maps because they tend to have better credibility than computed levels. In the project proposed here, guidelines for monitoring and measuring noise levels will be developed, that can contribute to a combined product (measurement and computation) that has high quality and high credibility. Noise action plans shall be based on strategic noise maps. The IMAGINE project will develop guidelines for noise mapping that will make it easy and straightforward to assess the efficiency of such action plans. Traffic flow management will be a key element of such action plans, both on a national and a regional level. Noise mapping will be developed into a dynamic process rather than a static presentation of the situation. IMAGINE will provide the link between Harmonise and the practical process of producing noise maps and action plans. It will establish a platform where experts and end users can exchange their experience and views. This platform should continue after the project and provide a basis for exploitation to the IMAGINE results.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'photonic system for Adaptable muLtiple-analyte monitoring of fOod-quality' (2014-2020) under Horizon 2020.

assistant: **Objectives**

h-ALO aims to develop and demonstrate in real-setting a new photonic-based sensor which will allow local food producers and retailers to control food quality and safety, therefore increasing competitiveness in the whole food production value chain. The sensor will provide:• Unprecedented high sensitivity, low limit-of-detection and large dynamic range compared to previously developed portable systems through the combination of an analyte pre-concentration and a multi-modal detection scheme;• Miniaturization and integration of optoelectronic and plasmonic components allowing portability in optical detection;• Multiplex-analyte recognition, allowing the unprecedented detection of both microbiological and chemical contaminants such as pesticides/antiparasitic, heavy metals, micro-organisms;• Easy and fast sample preparation protocols which are adaptable for a wide range of food samples;• Measurement automation and fast response, making the sensor reliable for on-site use by farmers, retailers and non-expert operators;• Mobile-phone connectivity and cloud-based data management allowing a distributed, anonymous food monitoring along the farm-to-fork chain.The innovative technologies at the basis of the h-ALO sensor are:i) highly integrated organic/hybrid photonic components as light-source and photodetector;ii) nanoplasmonic biofunctionalized surface assessing innovative multimodal optical transduction;iii) innovative aptamer- and immunoassay-based bio-recognition elements for multiplexing; iv) a smart microsieve membrane for analyte pre-concentration.The h-ALO prototype will be validated in lab by quantitative comparison with benchmark commercially available methods and demonstrated on-site in small selected agri-food chains such as aquaponics, craft beer, raw milk and orga
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Myelin Membrane in Molecular Detail' (MyeMembrane) under Horizon Europe.

assistant: **Objectives**

Myelin plays a critical role in rapid action potential propagation and support of neuronal metabolism. Disruptions of its formation lead to severe neurodegenerative conditions, with multiple sclerosis (MS) ranking as the most prevalent demyelination disorder in the central nervous system (CNS). The Multiple Sclerosis International Federation estimates that around 2.9 million individuals worldwide are affected by MS in 2023, and its prevalence is increasing yearly. It is well established that myelin-specific membrane-embedded and membrane-associated proteins are essential for wrapping the oligodendrocyte membrane around the axons, forming the tightly packed membrane multilayers, constituting the myelin sheath. While the molecular identity of these proteins is known, there is no high-resolution structural information for any of the full-length CNS myelin proteins, and it is unknown how these proteins interact among themselves and with the surrounding membrane to form the myelin sheath. MyeMembrane seeks to throw structural insight on the myelin sheath assembly by visualizing principal CNS myelin membrane proteins in a lipid environment at high resolution, and to investigate the interplay between myelin proteins and the surrounding membrane using cutting-edge biophysical techniques. Unravelling the structural basis of myelin sheath formation is crucial for understanding myelin disorders, and for exploring new research avenues including the development of new treatments, endowing MyeMembrane with far-reaching scientific and societal impact.


**Keywords:** myelin structure, cryo electron microscopy, membrane protein structure, neurobiology
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Fluently - the essence of human-robot interaction' (Fluently).

assistant: **Concept**

Fluently leverages the latest advancements in AI-driven decision-making process to achieve true social collaboration between humans and machines while matching extremely dynamic manufacturing contexts.The project results will be: 1) Fluently Smart Interface unit and 2) the Robo-Gym.The Fluently Smart Interface unit features: 1) interpretation of speech content, speech tone and gestures, automatically translated into robot instructions, making industrial robots accessible to any skill profile; 2) assessment of the operator’s state through a dedicated sensors’ infrastructure that complements a persistent context awareness to enrich an AI-based behavioural framework in charge of triggering the generation of specific robot strategies; 3) modelling products and production changes in a way they could be recognized, interpreted and matched by robots in cooperation with humans. Robots equipped with Fluently will constantly embrace humans’ physical and cognitive loads, but will also learn and build experience with their human teammates to establish a manufacturing practise relying upon quality and wellbeing. The bond between human and robot is personalized, and it is established during a preliminary training at the Robo-Gym, the first European hub for human-robot interactive training, where human and robot learn from each other a common work practice. Fluently will be validated by demonstration on three full scale pilots characterized by various level of automation, production dynamism and complexity of the manufacturing decision making process.The total project value required to commercialize the Fluently device and Robo-Gym concept is 18.8 M EUR. Forecast for EBITDA in 2028 is 16.3 M EUR, payback in 2028, with 13% gross profit and ROI 91% in line with sectorial performances. T
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Single-molecule magnets based on the orbitally-degenerate spin centers and stable organic radicals complexes'.

assistant: **Concept**

The finding some polynuclear complexes can behave like magnets on the molecular level attracted much attention, opening perspectives for their applications in processing devices or for high density information storage carriers. To manifest single-molecule magnet (SMM) behaviour a polynuclear complex should have a high-spin ground-state and strong negative anisotropy (D). The energy barrier, U, separating two spin orientations (up-down) is proportional to the product of │D│ and square of spin, S. Therefore the larger the D and S values are the higher the U barriers should be and the longer the magnetization might be blocked. However, such single-molecule magnetization is so far only observed at temperatures too low to allow an application.The project aims to rise the blocking temperature by increasing the U. Our approach is based on heterospin polynuclear complexes assembling involving orbitally-degenerated 4d, 5d metal centres (Os, Ru) and 3d metal ions or/and nitroxide radicals. If the utilisation of the first guaranties the strong anisotropy, the use of the stable radicals as ligands and bridges assures well isolated high spin ground-state owing to the strong exchange interactions between spin carriers. The synthesis work will be complemented with structural analysis and magnetic studies of these systems to elucidate the magnetic interactions as well the magnetic anisotropy in conjunction with theoretical magneto-structural analysis. A major goal of the project is to discover some rules for the rational design of polynuclear cluster systems with elevated blocking temperatures. The project results will document the coordination chemistry of 4d and 5d ions with nitroxides, a field lacking of fundamental results. The complexes will bring experimental opportunity to test
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Genetics, functional genomics, and bioinformatic approaches to disease gene discovery in the metabolic overlap syndromes in insulin resistance, type 2 diabetes, visceral obesity and dyslipidemia' in the context of a Fifth Framework call.

assistant: **Objectives**

I propose to combine sequence data and analytical tools from the human and other genome projects with results from differential gene expression studies and genetic linkage to identify a susceptibility gene for a complex genetic trait, combined hyperlipidemia, and to determine the role of the normal gene product in lipid transport and metabolism.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Gamification and Datafication towards Learning Forecasting' (GANDALF).

assistant: **Innovation**

A full 90% of all the data in the world has been produced over the last two years and the challenge of our society is to turn a world full of data into a data-driven world. Whereas the impressive progress in predictive analytics let us have insight on everything, our motivational resources are limited to learn and understand our reality. Today, gamification is regarded as a promising technique to improve motivational affordance in domains where people have difficulty of engagement such as data analytics and forecasting education.In this regard, the GANDALF project proposes the design of gamification and datafication solutions, which aims at improvement of learning outcomes in the context of forecasting course and demonstrate a world view based on facts. GANDALF aims to experimentally investigate gamification effects on educational process of a forecasting techniques’ course by addressing three novel objectives: (1) Design, implement and use a web-based, modular, educational platform in order to teach exploratory data analytics (module 1) and forecasting time series methods (module 2); (2) Investigate behavioural and psychological effects of individual affordances on learning exploratory analysis and promote fact-based world-view; (3) Examine behavioural and psychological outcomes in the context of a forecasting time series methods course. GANDALF employs controlled experimental research methods, with pre-, post-test design and forecasting problems to gain knowledge on the gamification effect on learning, user-experience and users’ forecasting accuracy based on their characteristics as well.GANDALF, along with its innovative points, contributes not only to civic understanding of data, but also to investigate how to effectively motivate users to explore data insights. In
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Identification of Novel Proteins Involved in Neuronal Polarization', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

Carrying out this project will give me the opportunity to acquire new knowledge in Molecular Biology and Neuroscience in a high quality group with publications in the best international journals. It will also give the opportunity to learn new techniques on molecular biology, immunocyto chemistry, microscopy) from expert people working during that period at the EMBL. One of the main interests of the Cell Biology and Biophysics Program at EMBL is to understand the mechanisms that generate and maintain cellular organization. In particular, the work at Dr. Dotti's focuses in understanding polarized sorting and trafficking during neuronal development. My work will contribute, with the identification and characterization of new proteins targeted to the axonal growth cone while axon formation occurs, or involved to axonal or dendritic protein transport in fully mature neurons, to understand the mechanisms leading to morphological and functional polarization in neurons.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Frankfurt university large scale facility for biomolecular mr' under Fifth Framework.

assistant: **Concept**

Description:The Frankfurt University Centre for Biomolecular NMR which is operated by the Institute of Biophysical Chemistry and the Institute of Organic Chemistry was opened on 1 February 1996. The main purpose of the facility with respect to structural genomics is the determination of solution structures of proteins and nucleic acids using multidimensional NMR and EPR spectroscopy. Within the facility access is available to the following installations:- Avance 900 MHz,- DRX 800 MHz- Avance 800 MHz with cryoprobe- Avance 700 MHz,- DMX 600 MHz with cryoprobe- DRX 600 MHz- DRX 600 MHz- DRX 600 MHz- Avance 600 MHz WB for solid-state NMR- DRX 500 MHz- DMX 500 MHz- Avance 400 MHz WB for solid-state NMR- DRX 400 MHz- 3 GHz pulsed EPR- 9 GHz pulsed EPR/ENDOR- 9 GHz CW EPR/ENDOR- 180 GHz pulsed EPR- 35 GHZ pulsed EPR/ENDOR- 180 GHZ CW EPR spectrometer.- Available are also workstations and other computer facilities,- fermentation and biochemical installations for stable isotope enrichment including the cell-free protein production. The minimum of access offered will be 195 NMR and EPR spectrometer days for a period of 2 years. This access will be provided free of all charge to the user groups given access to the facility and will include all infrastructural, logistical, technical and scientific support (including training courses) that is normally provided to external users of the facility.Application:Formal proposals are required for alloting the measurement time on the NMR and EPR spectrometers and provide the computational, technical and personal support needed. The proposal has to be sent together with a formal letter of application and the completed form for the pre-screening committee to Prof. Heinz Rueterjans (forms may be reproduced from the homepage). The preselection
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Computational Multiscale Neuron Mechanics' (COMUNEM).

assistant: **Innovation**

The last few years have seen a growing interest for computational cell mechanics. This field encompasses different scales ranging from individual monomers, cytoskeleton constituents, up to the full cell. Its focus, fueled by the development of interdisciplinary collaborative efforts between engineering, computer science and biology, until recently relatively isolated, has allowed for important breakthroughs in biomedicine, bioengineering or even neurology. However, the natural “knowledge barrier” between fields often leads to the use of one numerical tool for one bioengineering application with a limited understanding of either the tool or the field of application itself. Few groups, to date, have the knowledge and expertise to properly avoid both pits. Within the computational mechanics realm, new methods aim at bridging scale and modeling techniques ranging from density functional theory up to continuum modeling on very large scale parallel supercomputers. To the best of the knowledge of the author, a thorough and comprehensive research campaign aiming at bridging scales from proteins to the cell level while including its interaction with its surrounding media/stimulus is yet to be done. Among all cells, neurons are at the heart of tremendous medical challenges (TBI, Alzheimer, etc.). In nearly all of these challenges, the intrinsic coupling between mechanical and chemical mechanisms in neuron is of drastic relevance. I thus propose here the development of a neuron model constituted of length-scale dedicated numerical techniques, adequately bridged together. As an illustration of its usability, the model will be used for two specific applications: neurite growth and electrical-chemical-mechanical coupling in neurons. This multiscale computational framework will ultima
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Creating a Sustainable Functional Food Chain: A Pathway to EU Climate Neutrality and Improved Health' under Horizon Europe.

assistant: **Concept**

PATHFOOD aims to revolutionise the field of selenium-enriched functional food, aligning with the European Union's strategic objectives for sustainable development, public health improvement, and socioeconomic growth, thereby strengthening the University of Warsaw's (UW) standing as a leading institution in this research domain. It is a conduit for knowledge transfer and capacity building with internationally leading partners.The project integrates multiple facets, from selenium sourcing with robust traceability systems to innovative crop cultivation methods that enhance selenium content while minimising environmental impact. Additionally, the project focuses on optimising food processing techniques to preserve selenium content and develop consumer-tailored functional food products. Advanced analytical methods such as high-performance liquid chromatography (HPLC) and high-performance thin-layer chromatography (HPTLC) will be utilised to scrutinise selenium content and its speciation. Regulatory compliance forms a cornerstone, ensuring consumer health and instilling confidence in selenium-enriched food products.Adding to these dimensions, PATHFOOD is committed to achieving gender and diversity balance within the consortium throughout the project's activities. All participating partners established policies (GEP) designed to foster gender equality, diversity, and inclusion amongst employees, enriching the project's social impact.Furthermore, the project espouses an Open Science approach, aiming to make the research process more transparent and collaborative. This will facilitate the sharing of methods, data, and findings with the broader scientific community, thereby accelerating the pace of discovery and ensuring that the research benefits are distributed more widely. The