RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Agenda for Research on Chernobyl Health (ARCH): to develop of a Strategic Plan for Research on the Health Consequences of Radiation from the Chernobyl Accident' (ARCH).

assistant: **Innovation**

The Chernobyl accident led to the most serious exposure of a normal human population to ionising radiation, apart from the atomic bombings in Japan. Unlike the bombing, the health impact of Chernobyl has not been comprehensively studied. In some areas (eg thyroid cancer), research has been intensive and informative; in others, little work has been conducted. The validity of extrapolating radiation risk estimates mainly based on atomic bomb studies to exposures of public health concern is controversial. Questions relate to the choice of models for transport of risk between populations; projection of risk over time; extrapolation of risks from external high dose-rate exposure to low dose and low dose-rate exposures from internal radiation. Questions also concern non-cancer risks and the importance of non-targeted effects following low levels of radiation. Chernobyl has an iconic status in the public eye, and the accident provides a unique opportunity to answer these questions, to provide the authoritative studies needed to inform the nuclear debate, and to test novel hypotheses about radiation effects and biology/genetics in general. Because the range of potential studies is so vast, this proposal is for the development of a strategic research agenda on the health consequences of radiation exposure from the Chernobyl accident. The modus operandi will be the assembly of a multidisciplinary group of experts, from within and outside the most affected states, who have considerable experience in the follow-up of the health consequences of the accident. The group will identify and prioritise (short and longer-term) the potential studies, assess their feasibility, cost effectiveness and likelihood of success, and provide a reasoned and comprehensive strategic agenda for future r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Unraveling the interplay between food intake with endocrine factors in brown adipose tissue activation (FoodBAT)'.

assistant: **Objectives**

The last five decades have been characterized by an increase in obesity and cardiometabolic diseases. Recent predictions indicate that more than 1 billion people will be obese by 2030 worldwide. Contrary to white adipose tissue, brown adipose tissue (BAT) dissipates energy as heat and has been considered an important target for treating obesity and cardiometabolic diseases. Nevertheless, little is known about the interaction between diet, of the most important modifiable risk factors for cardiometabolic diseases, with BAT function. To develop new weight-loss strategies, it is essential to understand how food intake modulates BAT function by interacting with endocrine factors and how this interaction affects diet-induced thermogenesis in lean individuals and those with obesity.Recent data indicate that DIT is associated with BAT function and that gut hormones play an important part in the activation of BAT during the postprandial phase. Yet, the mechanism remains to be elucidated. Moreover, it is unclear whether DIT and cold-induced thermogenesis (CIT) share similar metabolic pathways and how the manipulation of food intake can affect BAT and, thus, energy expenditure.The main aims of FoodBAT are to investigate how the acute intake of a mixed meal modulates gut hormones to stimulate diet-induced thermogenesis (DIT) and BAT oxidative metabolism and to understand how this interplay differs between lean and obese individuals. Also, we will investigate how a cold acclimation protocol affects this interaction to modulate DIT in individuals with obesity. Finally, FoodBAT will unravel the connections and differences between DIT and CIT by comparing the gene expression and mitochondrial respiration of brown adipocytes stimulated with either nutrient overload, isoproterenol, or a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Decision support and knowledge driven collaborative practices in Palliative care' under Sixth Framework.

assistant: **Concept**

PALLIANET objective is to support knowledge driven collaborative practices in order to minimise risks in the context of palliative care. The project aims at conceiving an advanced solution supporting the needs of city professionals by combining a Community and Knowledge Management service, Advanced human-computer interaction features that makes access for caregivers easy and natural, and Coordination Facilities that would enable to maintain the quality and relevance of knowledge and in particular to analyse the way in which patients cases have been handled in order to measure the risks associated to palliative care; assess their costs; make explicit new Best Practices that can be disseminated through Best Practice Guides" and possibly revise the semantics to improve knowledge accessibility.This raises a number of Technological Research Objectives: Reference Ontology, EHR Contextualisation, Natural language for Ontology filtering, Knowledge Management and Community of Practice and Knowledge Generation. By support Health Professionals in implementing knowledge driven collaborative practice and providing them with relevant Knowledge and Advice, PALLIANET is in line with the IST prioriority objective of supporting health professionals in taking promptly the best possible decision for prevention, diagnosis and treatment. The consortium constituency has been set up to ensure visibility through user organisations well known in the palliative care area. Moreover, OIS and Airial have already a strong presence in the IT healthcare market and have the ability to reach a pan-European market.This approach is also supplemented by clear plans for IP protection in order to enable licensing the developed technologies through commercial variants. Pilot Actions will be conducted in France
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The role of ciliary tip organization in hedgehog signaling' (CiliaryTip) under Horizon 2020.

assistant: **Objectives**

Cilia are microtubule-based organelles with essential motile, sensory and signaling functions. The cilium structure is important for its function however the mechanisms underlying the structure-function relationship are not well understood. The proposed study will address the role of the cilium structure in hedgehog signaling, one of the main cilia-based signaling pathways, essential for embryonic development and implicated in disease. In mammals, cilia are required for hedgehog signaling and the localization of signaling proteins at the distal end of cilia, the ciliary tip, is important for pathway activation. Structural defects at the ciliary tip affect the localization of signaling proteins and pathway activation and cause a subset of cases of Joubert Syndrome. We propose an unbiased and comprehensive approach to elucidate how the ciliary tip organization supports the localization and dynamics of hedgehog signaling proteins at this compartment. This work will impact how we address hedgehog related diseases in the future and will generate insights with broader implications with respect to the signaling and sensory roles of cilia. The fellow will conduct this work in the laboratory of Dr. Skourides at the University of Cyprus, a group with a consistent record of high quality publications, including important findings related to cilia. The Fellow’s experience in studying the ciliary tip in motile cilia and the expertise of the host in cellular and developmental biology ensure the successful implementation of the proposed work. The Fellow has demonstrated great potential in becoming an independent scientist by securing funding for her PhD work and receiving the Seal of Excellence on an MSCA-IF submitted in 2018. Through this fellowship the researcher will acquire both th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'New Quality and Design Standards for Aluminium Alloys Cast Products'.

assistant: **Objectives**

To exploit the enormous potential of Aluminium Alloys EU Foundry Industry (more than 2000 Companies, mostly SMEs), a coordinated set of Support Actions, is strongly needed. The challenge of StaCast proposal is to promote the transformation of this field in a quality/efficiency-driven and integration-oriented sector, thanks to the development and introduction of two new and advanced Tecnhical Reports, covering aspects which are not approached in current norms: Casting Defects Classification and Aluminium Foundry Alloys Mechanical Properties.In view of this target, StaCast Consortium, in which 4 European Countries are represented, is highly complementary and constituted by: one University Dept (DTG, Co-ordinator), well used at cooperating with SMEs, special in the field of Aluminium alloys;  two other University Depts, with a relevant background on gravity (NTNU) and high pressure (GTA) casting technologies;  one National Association of Metallurgical Companies (AIM), with more than 2000 members; one EU Association of Aluminium Consumers (FACE); one member of Italian National Standardisation body (ASSO).StaCast project will convert in specific CEN Technical Reports the results of previous EU-funded research projects (e.g. IDEAL in the 5th FP and NADIA, IP-SMEs, in the 6th FP) as well as of other National and International technological developments programmes. The consistent set of activities of StaCast, whose duration is 18 months, is articulated into 6 WPs, logically organised to focus the standardisation needs (WP 1), to support the development of new CEN Technical Reports on Al alloy casting defects (WP 2) and on Al foundry alloys mechanical properties (WP3), to elaborate new guidelines for using such Technical Reports in mechanical design (WP4), to disseminate the kno
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Understanding Latin American Challenges in the 21st Century' (LAC-EU), addressing dissemination and exploitation.

assistant: **Impact**

Social, political, and cultural transformation, a fast-changing global economy, geopolitical tensions and global uncertainties have created a markedly different context from the previous era of European Union (EU) policies towards Latin America and the Caribbean (LAC). The doctoral network LAC-EU will establish a novel, comprehensive and interdisciplinary framework to understand LAC and its relationship with the EU, fostering respectful, non-Eurocentric research and engagement. It will enable a better understanding of current challenges in Latin American governance and support sustainable, equitable and successful relations between the EU and LAC.LAC-EU offers doctoral candidates an outstanding, integrated four-year PhD programme and provides world class, interdisciplinary research and training in social and political sciences, law and the humanities, as well as research exchanges and policy-relevant secondments at associated partners in the EU and LAC. Research themes within LAC-EU include the rise of populism, democracy, gender rights, trade, migration, health, global cities, sustainability and green finance and cultural learning. The LAC-EU doctoral programme comprises an interdisciplinary, multi-sectoral network composed of four leading European universities, an outstanding LAC higher education institution and key, highly relevant civil society and policy partners from a range of European and LAC countries. It offers an exceptional combination of academic and research-related training and transferable skills to deliver scientific excellence, occupational mobility and preparation for lifelong, policy-relevant learning for a new generation of researchers. Furthermore, it provides the EU with the vital inputs needed to design coherent, sustainable, equitable and compre
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Efficient decommissioning, repurposing and recycling to increase the circularity of end-of-life wind energy systems.' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

REWIND aims at developing critical technologies for dismantling end-of-life (EoL) wind turbine blades (WTB) (evaluation, advanced cutting, etc.) and implementing new methodologies for composites repurposing and recycling (catalytic pyrolysis and solvolysis) to increase the circularity of WTB, increasing the industrial applications of the EoL composites, and avoiding the current landfilling or incineration. The main composition of the composite waste is expected to be epoxy resin/carbon fibre (CF), epoxy resin/glass fibre (GF) and polyester resin/GF. The new methodologies will address the following challenges: 1) Study and development of suitable disassembly, quality inspection and characterisation of the composite waste, to be able to understand composite waste properties. As a result, it will be possible to decide if composite parts from EoL products should be repurposed or recycled depending on their value. 2) Show potential high-value applications for composite end-of-life: repurposing will be demonstrated through manufacturing 2 demonstrators (for construction and automotive sector). This will be done by matching specified requirements with dismantled materials using software and hardware tools to facilitate the fragmentation processes. 3) New innovative pyrolysis and solvolysis methods for recycling will be developed and tested to significantly reduce the processing temperature and time for those parts that cannot be used in repurposing. This will allow to save energy, and together with the post-treatments, improving the quality of the materials recovered (e.g., weaved fibres, sized fibres, recycled polyester resin, recycled epoxy resin and epoxy vitrimer resins based on recycled monomers). Secondary raw materials obtained will be used to manufacture 2 demonstrator
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Research and training network: language and brain' (2002-2006) targeting Sixth Framework.

assistant: **Abstract**

Objectives The Research and Training Network: Language and Brain (RTN:LAB) is composed of researchers dedicated to solving the mysteries of language organization in the brain. Our objectives are: * to integrate and expand current knowledge of brain process es that lead to word recognition; * to form a better understanding of how biological, perceptual, cognitive and environmental effects interact to form language systems in the brain; * to establish an active long-lasting network of collaborations and person nel exchange between leading institutions in cognitive neuroscience and cognitive psychology; * to overcome inter-disciplinary barriers by exchanging complementary skills between different groups. Work plan We propose four complementary research themes tha t eventually will merge to suggest a multi-factorial explanation of language development. First, we will study biological factors underlying the development of language. Second, we will focus on perceptual and cognitive aspects of word recognition. Third, we will evaluate environmental factors on language development. Finally, we will look at lifelong language development. These four research themes will each involve four projects each, where we will use state-of-the-art experimental paradigms borrowed fro m psychology, neuropsychology, and neuroscience. Relevance to the FP6 Marie Curie Research Training Networks objectives Mobility: RTN:LAB will provide students and more experienced researchers with opportunities for collaboration across laboratories, betwe en disciplines and between European states. Gender: 33% of the RTN:LAB are women scientists, and we offer an attitude-change tutorial in gender and science issues as part of the training. Less-favoured-areas (LFA): one research team is from LFA (Oviedo) an d t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Subsea Tools Application Research' to be submitted under Fourth Framework.

assistant: **Abstract**

The project consists of a consortium of companies and research organisations working together to research, design and develop tools for subsea use in diverless operation. Prototypes will be developed that will demontrate the practicality of the engineering principles which result from the project. The tools will attach to the robot arm of ROV's and AUV's engaged in subsea exploration and exploitation, particularly in the transition toward deepsea working. This will increase the range of tasks able to be perfomed by the submersibles and in doing so will reduce costs of subsea activity, speed up operations, reduce risk to the environment and provide EU SME's with world class products.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Analysis of fiber type-specific regulation of muscle genes by gene transfer in regenerating muscle'.

assistant: **Concept**

1) Identify the regulatory sequences responsible for the fiber type-specific expression of muscle genes by progressive deletions and site directed mutagenesis. Constructs containing portions of the 5' flanking regions of a gene expressed in slow muscle fibers, (the myosin light chain 2 slow/ventricular gene), and a gene expressed in fast fibers (the MyHC-2X gene), will be linked to reporter genes and used for direct injection of plasmid DNA into fast and slow regenerating skeletal muscles that will be subsequently analyzed. 2)Determine the capacity of skeletal muscle to produce and deliver systemically recombinant serum factors. Appropriate promoter/enhancer combinations are essential for a successful gene therapy. The information obtained from 1) will be used to determine the role of muscle-specific regulatory sequences (alone or with viral promoters/enhancers), in driving the expression of the rat growth hormone gene. This gene will be transfered into muscles of hypophysectomized rats and blood levels of GH and its effects on body growth will be determined.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'European access to the facilities of the Berlin Neutron Scattering Center (BENSC)' in the context of a Fourth Framework call.

assistant: **Objectives**

The Berlin Neutron Scattering Center at the upgraded reactor BER II is Germany's most modern facility for cold and thermal neutrons. The neutron beam time is mainly available to external users, with 50% of the beam time being allocated for short-term research proposals of external users, 20% to long-term cooperations. Inclusion of new projects and priorities are decided upon by an international scientific panel. Neutron scattering provides important and unique information about structural, dynamical and magnetic properties of condensed matter, which in many cases cannot be gained by other methods. BENSC offers access to a great variety of new or upgraded neutron scattering instruments. There is special emphasis on sample environment under extreme conditions (e.g. high fields, high pressure, high, low and ultra low temperatures - and combinations of these special conditions). During the first 2 years operation, research at BENSC has been carried out in many fields of science, e.g. solid state physics, biology, crystallography and structural chemistry, and fundamental and applied material science. The access for numerous European groups has been funded under the HCM programme. It is the aim of the present proposal to continue these successful European collaborations and to open BENSC to new users. Moreover, BENSC offers possibilities for novel spectacular experiments with the new device for experiments at extreme ultra low temperatures.