RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'A Nanoscale Artificial Nose to easily detect Volatile Biomarkers at Early stages of Lung Cancer and Related Genetic Mutations' to be submitted under Seventh Framework.

assistant: **Abstract**

The LCAOS project will develop and test a new diagnostic tool, able to detect:(i) the presence of lung cancer (LC), and(ii) an increased risk of a patient developing LC in the future.Diagnostic tests currently available are unsuitable for widespread screening because they are costly, occasionally miss tumours, are not time-efficient, nor free of complications.LCAOS will overcome these problems by using an approach based on volatile biomarkers emitted from cell membranes. A multidisciplinary effort, incorporating nanotechnology, biomedical engineering, medical oncology, and computation strategies, will develop a highly-sensitive, inexpensive, and fast-response, non-invasive, artificial nose (known as, NaNose), building on the coordinator’s earlier success in this area. The NaNose will be able to detect pre-neoplastic volatile biomarkers that indicate an increased genetic risk of LC, and the presence of LC. It has already been established that these biomarkers can be detected either directly from the headspace of the cancer cells or via exhaled breath.LCAOS will:(i) develop arrays of chemically-sensitive field effect transistors (FETs) of non-oxidized, molecule-terminated silicon nanowires (Si NWs);(ii) test the ability of these devices to sense volatile LC biomarkers from in-vitro tissue, and exhaled human breath;(iii) study the signal transduction mechanism of the volatile biomarkers, using pattern recognition;(iv) improve systems to enable the NaNose to distinguish the targeted biomarkers from environmental clutter, using methylation, expression profiling, and genome-wide sequencing; and(v) perform clinical-related studies to assess LC conditions in actual patients & tissues, and in the presence of real-world confounding signals.Validation will be carried out by clinic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Novel Hydrogen Storage System' (H2STORES).

assistant: **Innovation**

In the project H2StoreS, standing for novel Hydrogen Storage System, a proof of concept (PoC) of novel liquid-organic hydrogen carrier (LOHC) technology will be conducted. The aim of this PoC is to create and document the technical and business environment analysis- based evidence of near term commercial potential of this novel hydrogen storage system. Moreover, another important goal of this project is to find the right post-PoC phase technology development, commercialisation and funding partners, and to convince them in investing funds and effort in this technology.Molecular hydrogen (H2) is a very attractive clean, renewable fuel, which can also be used for energy storage and heating systems. H2 is currently stored in high-pressure or cryogenic tanks. However, these solutions are not suitable for most commercial applications because of their low energy density, high price and safety issues. All these problems can be avoided using LOHC systems and consequently, there have been a lot of research and development efforts in this field during recent years.The ability to store and transport H2 within a liquid carrier at standard temperatures and pressures provides many advantages over current H2 storage methods; the need for large storage tanks is eliminated, major changes in the fuelling infrastructure are avoided and the risk of explosion is minimised. However, although significantly more cost efficient than high-pressure or cryogenic tanks, current state-of-the-art LOHC systems remain too expensive for a large-scale consumer use of H2.Within the preceding ERC project, a liquid-organic hydrogen storage system was discovered, which provides significant technical and commercial advantages and has the potential to enable the large-scale use of H2 as an energy storage vector
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Error-correcting codes and their applications in Science and Engineering' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Error correcting codes are combinatorial objects which have traditionally been used to enhance the transmission of data on unreliable media. They have experienced a phenomenal growth since their birth some fifty years ago. Today, everyday tasks such as listening to a CD, accessing the hard disk of an electronic device, talking on a wireless phone, or downloading files from the Internet are impossible without the use of error-correcting codes. Though traditional communication still occupies centerstage in the realm of applied coding theory, emerging applications are changing the rules of the game, and calling for a new type of coding theory capable of addressing future needs. These are not limited to physical applications, however. In fact, coding theory is an integral part of solutions offered by researchers outside traditional physical communication to solve fundamental problems of interest, such as the complexity of computation, reliable transfer of bulk data, cryptographic protocols, self correcting software, signal processing, or even computational biology.While research in the past fifty years has put traditional coding theory on firm theoretical grounds, emerging applications are in need of new tools and methods to design, analyze, and implement coding technologies capable of dealing with future needs. This is the main concern of the present proposal. To strike the right balance between length and impact we have identified five areas of research that span the full spectrum of coding theory ranging from fundamental theoretical aspects to practical applications. We set out to develop new theoretical and practical models for the design and analysis of codes, and explore new application areas hitherto untouched. A unique feature of this proposal is our choice of the t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Mobile Application for Hybrid Internet' in the context of a Horizon 2020 call.

assistant: **Objectives**

Internet is a significant driver for the economy nowadays. The impact of improved connectivity will increase mainly since the predictions for 2020 show a number of 80Bn-connected devices. Mobile Internet will play a key role in bringing the users online, as the number of smartphones has notably grown. A global perspective on Internet usage highlights critical infrastructure deployment, expansive technology, declining prices and worldwide access. The Internet Service Providers (ISP) are struggling to improve their services in terms of speed, reach and reliability, handling the variety of smartphones. The main challenges refer to the abilities of current TCP-based protocols to handle simultaneous Internet connections to different networks, limiting the resilience of mobile devicesIETF, with the support of Tessares’ team, introduced Multipath TCP (MPTCP), a standard protocol more fit for the wireless environment to enable greater speed and increased resilience. Current deployments of MPTCP have required the software to be deeply integrated into the kernel of the device’s operating system, which is a lengthy and complex process, limiting its use to just a few devices. Tessares proposes a smartphone Multipath App (MPA) that simultaneously combines broadband and Wi-Fi networks for better speed, reliability and on-the-move consistency. Based on a MPTCP protocol running in the user space, not in the kernel, MPA will assist smart bonding of the most widely used smartphone access network technologies. MPA will streamline over the ISPs access network, leveraging their infrastructure by enabling flexible bonding, periodic upgrades, constraints free for every smartphone and operator-branded application. Easy to deploy on most current and future smartphones, MPA is expected to be in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Petrographic and vOlatile SignaturEs of prImitive and Differentiated achONdrites' in the context of a Horizon 2020 call.

assistant: **Objectives**

The “Petrographic and vOlatile SignaturEs of prImitive and Differentiated achONdrites” proposal aims to determine the water content and its hydrogen isotopic composition in nominally anhydrous minerals (NAMs), from a range of achondrite meteorites, using a combination of three techniques, namely transmission infrared spectroscopy, reflectance spectroscopy and nano secondary ion mass spectrometry. The leading goal is to estimate bulk-parent body volatile abundances of achondrites, which were among the first planetesimals formed in the Solar System, to develop a robust understanding of the distribution and source(s) of water in the inner Solar System. This project also aims at developing reflectance spectroscopy as a possible tool for direct/indirect estimation of water content by cross-calibration of multi-techniques. Four tasks have been elaborated to perform this proposal: 1) petrographic characterization of achondrites, 2) transmission and reflectance spectroscopy of achondrites, 3) secondary ion mass spectrometry of achondrites, 4) dissemination of results. The proposed study will be the first comprehensive study of its kind, combining a new approach using multi-techniques methodology for measuring volatile abundances and isotopic composition in NAMs, exploiting recent improvements in analytical techniques, developing new protocols for reflectance spectroscopy, and studying a range of planetary materials never studied before. The results from our work would make timely key contributions towards the ongoing debate of ‘wet’ vs. ‘dry’ scenario for accretion of volatiles in the inner Solar System as well as implications for the timing of water accretion into planetesimals, which is essential for developing dynamical models of Solar System formation. As such, this study i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Urban Sensing through User Generated Contents' in the context of a Seventh Framework call.

assistant: **Objectives**

The project aims at bringing a new product to the urban design, city planning and urban management market: a platform extracting patterns of use and citizens' perceptions related or concerning city spaces, through robust analysis of User Generated Content (UGC) shared by the city users and inhabitants over social networks and digital media.Traditional data collection methods - such as surveys, interviews and ethnographic observations –have some limitations: high cost in terms of time and resources and limited size of the samples they can generally cover. More recently, methods based on real-time data and web harvesting have been adopted, but a focus on their spatial and temporal dimension is still lacking.Now it is time to experiment with new methods, which are made possible by the fact that an increasingly high number of citizens can produce and share geolocalized information about their everyday life experience on searchable social platforms such as Twitter, Facebook, Foursquare etc.Applying text mining and conversation analysis to geolocalized UGC Urban Sensing will provide meaningful indexes and dynamic maps depicting citizens' shared perceptions, emotions, hints and opinions regarding public services, urban spaces, time-based events, and the city as a whole. A set of visualisation tools, targeting the needs of the involved SMEs, provide interaction with this maps and indexes.Based on the specific needs of the SMEs, a wide range of indicators will be defined and validated through iterative tests to be performed in 3 different countries.It will provide an insight into understanding how public policies, spatial interventions, events and transformations are perceived within a city, and at the same time it will give hints to designers, developers and entrepreneurs adopt
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Tools and a methodology for acquiring high level knowledge from domain experts in the context of medical problem solving' under Fourth Framework.

assistant: **Concept**

Research objectives and content This project aims at investigating the potential for the dynamic acquisition of background knowledge in the context of semi automated systems which build or refine knowledge-bases. The principal idea to be explored is that the necessary expert knowledge is best acquired dynamically, at the time it is useful. This need appears during the system's operation, when a disagreement appears between the system's hypotheses and the user. It is through the justification by the expert of its previous judgments that we can incrementally narrow the gap between the system's knowledge and the expert's knowledge. This approach can be adopted to enhance an interactive machine learning algorithm designed as an aid to scientific discovery like PASTEUR (developed by the applicant), or to enhance a system for the refinement of existing knowledge bases like REFINER (developed at the host laboratory). The resulting systems will be evaluated on medical problems in collaboration with Aberdeen's Medical School. Training content (objective, benefit and expected impact) Benefit from internationally recognized excellence of Aberdeen Computer Science laboratory on both Knowledge Base Systems and computational research on scientific discovery. Apply and develop further the method developed during doctoral studies in the framework of the host's collaboration with the medical school. Links with industry / industrial relevance (22) The project will hopefully lead to the production of an operational system (such as a knowledge-base patient monitoring system) that could be used within the hospital in Aberdeen or elsewhere.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'High performance ceramics by near-net-shape forming processes (HYPERCER)' (HYPERCER), addressing dissemination and exploitation.

assistant: **Impact**

The project is directed to the development of new ceramic forming processes for complex and highly reliable ceramic parts used in several applications. Especially in biomedical applications, i.e. complex joints, there is no satisfying solution available up to date. Therefore the problem solving approach is related to the development of an ankle joint prosthesis system with a ceramic/ceramic wear couple . This extremely complex joint system has been selected since extremely high strength ceramics with more than 1000 MPa are required. The results can be transferred to other joints, like knee, finger and foot. Furthermore the results obtained in this project may be transferred to other industrial sectors like automative industry, either to be used as wear parts or even as cutting tools under dry operations, taking into account the environmental aspect and to avoid lubricants.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Optoelectrical Dynamics of Ion channel Activation in Calcium Nanodomains' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

In neurons, sites of Ca2+ influx and Ca2+ sensors are located within 20-50 nm, in subcellular “Ca2+ nanodomains”. Such tight coupling is crucial for the functional properties of synapses and neuronal excitability. Two key players act together in nanodomains, coupling Ca2+ signal to membrane potential: the voltage-dependent Ca2+ channels (VDCC) and the large conductance Ca2+ and voltage-gated K+ channels (BK). BK channels are characterized by synergistic activation by Ca2+ and membrane depolarization, but the complex molecular mechanism underlying channel function is not adequately understood. Information about the pore region, voltage sensing domain or isolated intracellular domains has been obtained separately using electrophysiology, biochemistry and crystallography. Nevertheless, the specialized behavior of this channel must be studied in the whole protein complex at the membrane in order to determine the complete range of structures and movements critical to its in vivo function. Using a combination of genetics, electrophysiology and spectroscopy, our group has measured for the first time the structural rearrangements accompanying whole BK channel activation at the membrane. From this unique position, our first goal is to fully determine the real time structural dynamics underlying the molecular coupling of Ca2+, voltage and activation of BK channels in the membrane environment, its regulation by accessory subunits and channel effectors.BK subcellular localization and role in Ca2+ nanodomains make these channels perfect candidates as reporters of local changes in [Ca2+] restricted to specific nanodomains close to the neuronal membrane. In our laboratory we have created fluorescent variants of the channel that report BK activity induced by Ca2+ binding, or Ca2+ bindi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Yeasts for the Sustainability in Viticulture and Oenology' (YESVITE).

assistant: **Innovation**

Modern viticulture and oenology were born in the last century responding to the need to innovate in traditional technologies. However, current economic, ecological and social changes require new strategies for wine production that take an integrated view of the entire wine production chain to ensure sustainability. Current management systems of vineyards and fermentations are indeed not economically or environmentally sustainable. The present proposal will approach this topic from both an environmental, focusing on the theme of biodiversity and its protection, and from an economic/social point of view. Optimization will promote the use of yeasts to reduce pests in pre/post-harvesting and to produce low-alcoholic and/or sulphite wines. In particular, the identification of fermentative yeasts isolated from ancient (Italy, Georgia, and Slovenia) and new (Sweden, Canada, and South Africa) vine-growing areas will allow the selection of species/strains that could be useful to evaluate both the possible interaction between genomes and phenotypes and the interplay of wine-related organisms in the oenological environment. Finally, the network aims to produce non-GMO yeasts for the participative selection of strains by the wineries. The consortium research units possess complementary competencies and are all working with success in wine research; partners have consolidated expertise in chemistry, biochemistry, microbiology, physiology, genetics, bioinformatics, and taxonomy. The level of quality of the involved institutions and the appropriate staff exchange scheme (early and experienced researches) will allow an efficient transfer of knowledge during three years and for long-term collaborations. The expected impact of the consortium will be to contribute to the wine research fie