RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Titles of the New Testament: A New Approach to Manuscripts and the History of Interpretation'.

assistant: **Innovation**

The problem this project addresses is that operative modes for interpreting the Greek New Testament (NT) rely upon critical editions, not manuscripts. NT editions are scholarly abstractions that focus on reconstructing an “original” text, and that fail to account for a rich manuscript tradition that preserves evidence for key disciplinary questions. Instead of asking how manuscripts help reconstruct a text, this project examines what manuscripts say about the ways the NT was interpreted by the communities that produced them. This is accomplished by comprehensively analysing the forms and wordings of the title preserved in all non-lectionary NT manuscripts (c. 3500). Titles are malleable paratexts that provide a substantive vector to rethink approaches to the NT by seriously considering contexts of production and interpretation ranging from 2rd century Egypt to modern Mt. Athos, moving beyond the 1st century Roman world. Titles demonstrate that material and paratextual variance in form and design are constitutive aspects of the NT. Adopting New Philology as a methodology, the project critiques dominant approaches by taking each manuscript seriously as evidence for specific reading events, using titles as primary evidence. Titular analysis informs a range of topics, including authorship, locales of production, contexts of use, bibliography, and literary interpretation. The NT is best understood as an omnibus of manuscripts that constitute specific reading events, reflecting the interpretations of the communities that used them. The NT has never been a single reconstructed text, but a collection of texts in specific material and paratextual contexts. Despite the value inherent in the manuscripts, scholarship has focused almost exclusively on the NT’s original context of co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Application of capillary electrophoresis for isolating bacteria and assessing ectoenzymes diversity and kinetics' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

A newly developed method is available now for routine use to fractionate alive complex bacterial communities from a diverse range of habitats to the species level (BAC-PACE). It is therefore the first and only method available at the moment, which allows the live isolation of single bacterioplankton populations, which can then be used for metabolic and physiological measurements and for biotechnological and pharmaceutical screening. The diversity and kinetics of bacterial ectoenzymes can be assessed by capillary electrophoresis (CERES) with an unsurpassed sensitivity. Thus isolation of bacteria and enzymes and their characterization can be directly done on environmental samples without the need of cultivating them first. Ultimately, sequencing will provide information on the phylogeny of the isolated bacterial species on which the various measurements were performed. All these mentioned techniques would be introduced both theoretically and by extensive hands-on instructions. Good background in microbiology and basic knowledge in chemistry is required.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Renormalisation, dynamics, and hyperbolic symmetry' (SPINRG), addressing dissemination and exploitation.

assistant: **Impact**

The objective of this proposal is to develop effective methods for the analysis of classical continuous spin systems, with focus on their stochastic dynamics and on spin systems with hyperbolic symmetry. The latter are related to reinforced random walks and to random operators. In particular, I propose to develop mathematical methods for renormalisation group analysis of such systems. Renormalisation is a central concept in theoretical physics, explaining a vast range of phenomena heuristically. While its rigorous implementation is difficult, when a renormalisation group approach to a problem is available, it provides very detailed control and also explains universality.Both, in stochastic dynamics of large scale systems and in random matrix theory, great progress has been achieved recently. In stochastic dynamics, this applies in particular to the problem of existence of solutions to SPDEs and their regularity (ultraviolet problem). This proposal focuses on the complementary regime of long time asymptotics (infrared problem), where important results have been obtained via exact solutions but robust methods remain scarce. In random matrix theory, very general classes of random matrices have been understood, yet those with finite dimensional structure like the Anderson model remain out of reach. Spin systems with hyperbolic symmetry and supersymmetry arise in the descriptions of such random matrices, and their simplified versions are prototypes for the understanding of the original models. They also describe linearly reinforced random walks which are of independent interest, and allow for some of the quantum phenomena to be reinterpreted probabilistically.I will build on methods that I developed in previous work, including renormalisation group analysis for static system
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Nitric oxide-driven anaerobic oxidation of lignocellulose' (NOD-AOL).

assistant: **Innovation**

In the riparian zone of eutrophic lakes and in field denitrification beds, microbial communities degrade lignocellulose, in anoxia, while maintaining a denitrifying lifestyle. During this process nitrate is converted to nitrogen gases via a series of reactions and intermediate products, fueled by the degradation of lignocellulosic biomass. The microbial interactions, metabolic pathways, and enzymatic mechanisms, underlining this remarkable process remain largely unknown. Intriguingly, in these anoxic habitats, enzymes involved in O2-driven oxidative lignocellulose conversion are found and expressed, yet their source of O2, their potential use of other oxidants, and their catalytic mechanism in anoxia remain unknown. Exploring this knowledge gap is a high-risk endeavor with potential to discover yet undescribed enzymes or enzyme systems capable of anaerobic oxidation of lignocellulose (AOL).I hypothesize that oxidative cleavage of lignocellulose under denitrifying conditions follows aerobic routes including lytic polysaccharide monooxygenases (LPMOs) and lignin-active oxidases, and further, that the activity of nitric oxide dismutases (NODs) provides a source of O2 for LPMOs and lignin-active enzymes. This is conceptually high risk, linking together biological processes in a new way. Herein I will scrutinize my key hypotheses by in-depth characterization of both LPMOs, lignin-active enzymes and NODs to a depth never done before. I will study whether LPMOs can employ relevant non-conventional denitrification-linked electron acceptors and use novel approaches for characterizing the enigmatic NODs.NOD-AOL is highly interdisciplinary and addresses questions central for understanding the global carbon and nitrogen cycles, which may ultimately help counteracting climate change
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Ultra-melt - innovative energy saving development for the injection moulding sector' in the context of a Fifth Framework call.

assistant: **Objectives**

The objective is to develop a prototype low cost, retro-fittable, ultrasonic melt system for the promotion of piastic flow in polymer processing, and an associated rheology calibration system. This will enable the EU polymer processors to reduce the energy consumption of the melt phase of polymer processing by up to 30%, allowing them the opportunity to produce thinner walled, performance products with standard melt flow index materials. This reduction in raw material consumption & energy, and improvement to product design, will lead to reduced cycle times and reductions in part cost of 23%. Together the proposers anticipate halting the alarming trend in out-sourcing outside of the EU, and recover 6% of the Euro 6 bn lost polymer GDP pa of imported polymer components & products (Euro 360 m/pa). It expected that the technology will be licensed to 1,910 SMEs each increasing their annual revenue by Euro 200k and generating additional emolcyment in the sector by 2,250 jobs. It is proposed than annual user license fee of Euro 2k will provide not-for-profit revenue for the IAG proposers to litigate against patent infringements and continue a programme of publication & dissemination - therefore providing a sustainable framework to support the SME exploitation after the RTD project. Furthermore, licences will be sold for sales networks, and for manufacturers of the system at Euro 25k/annum. The penetration of 10% of the injection moulding sector over 3 years will require a total of 1,910 systems, generating 538 new jobs and additional revenue of Euro 86 million. This will be serviced by 36 sales & manufacturing licensees in UK, Denmark, Spain, Italy, Germany and extended regions.%lWork description-To co-ordinate all project activity & act as the administrative interface to the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Research, development and demonstration of a novel non-invasive continence management system (NICMS)'.

assistant: **Innovation**

This proposal aims to develop practical non-invasive continence management system for people, particularly women, with severe continence difficulties. Research will build on the earlier work on the Active Urine Collection Device (AUCD). The success of this device relies on its unique ability to remove urine as rapidly as it is produced whilst using a very small battery operated pump. Research will be focussed on developing three types of user/device interfaces. European wide testing and improvement will ensure a significant breakthrough in continence management in the community.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Baltic Summer School 2003: Neurodegenerative diseases: mechanisms and principles of rational treatment'.

assistant: **Innovation**

Advanced training of young researchers is a most important factor for the future development of biomedical science and this is particularly true for clinical neurosciences with their rapid expanding approaches in diagnosis and treatment with molecular strategies. Based on regional links, collaboration and expertise in science and education the Medical Faculties of the Universities of Copenhagen, Kiel and Lund have established the Baltic Summer School (BSS) to combine their efforts in training of young researchers. BSS_2003 realizes the ambitious aim to bridge from bench to bedside. The conferences takes into account the urging necessity to shape the neurobiological research for the clinical demands, and inversely, to provide clinicians with the molecular details underlying the behavioural-neurological deficits.In consequence the BSS develops a well structured teaching platfom which guides the participants from: (1) pathological functions and signals of neurons and glia, and the corresponding regenerative-plastic adaptation to (2) the genetic burden of neurological disorder and the clinical relevance of neurobiological findings, and (3) culminates in the extensive molecular-neurological presentation of the major degenerative diseases such as Parkinson's, Alzheimer's and Huntington's disease, ALS and the neurodegeneration underlying psychiatric diseases.These fields have dramatically expanded because of the rapid scientific development and the need to cope with progressive neurodegenerative diseases, which are an economic burden to Society. BSS_2003 is thus timely from a scientific, technological and socio-economic point of view. The project is important for understanding basic mechanisms, but at the same time highly relevant for the development of new therapeutic strateg
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Power Amplifier Design Through Behavioural Modelling', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

5G base-stations will make use of large antenna arrays (hundreds of elements), potentially with each radiating element fed independently, meaning 1 power amplifier (PA) per element. This situation, combined with the trend of removing the circulator from the PA output for cost and size reasons, the design of the PA needs to take into account for the interaction with the other array elements. As a consequence, the simulation in CAD using traditional transistor models with a large number of internal nodes could become inconvenient, and the use of a behavioral model for the transistor could be an interesting choice.The project objective is to design 5G RF Doherty PAs for the 5G sub- 6 GHz band using transistor behavioral model. The Cardiff Model will be applied for the first time in a Doherty design, guiding the necessary model changes not only to adapt the model to this application, but also exploiting the advantages that the model can give. Moreover, thanks to his knowledge of Doherty, Jorge will identify a procedure to minimize the number of measurements needed to extract the model. In this way, Jorge will enhance his knowledge by working on behavioral modelling (model extraction, implementation in CAD, and modifications) and waveform measurements. CHFE will improve his range of expertise by hosting a design expert and developing the model for a timely and actual application.This research program is framed in one of the EU2020 targets, which is the efficient use of energy, as an important issue related to the climate change and energy sustainability of the world.  The expansion and increasing pervasiveness of wireless networks has significantly increased the impact of their power consumption.  By delivering a method to design efficient 5G PAs, PABLO will contribute to gr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Continuous Social Learning in Knowledge Networks'.

assistant: **Concept**

The agility of organizations has become the critical success factor for competitiveness and requires that companies and their employees together and mutually dependently learn and develop their competencies efficiently. Failures of organisation-driven approaches to technology-enhanced learning and the success of community-driven approaches in the spirit of Web 2.0 have shown that for that agility we need to leverage the intrinsic motivation of employees to engage in collaborative learning activities, and combine it with a new form of organisational guidance. For that purpose, MATURE conceives individual learning processes to be interlinked (the output of one learning process is input to the other) in a knowledge-maturing process in which knowledge changes in nature. This knowledge can take the form of classical content in varying degrees of maturity, but also involves tasks and processes or semantic structures. The goal of MATURE is to understand this maturing process better, and to build tools and services to reduce maturing barriers.MATURE's outcome will be1) an empirical analysis of real-world maturing practices, resulting in a sound conceptual model of the knowledge maturing process and ways to overcome barriers to it (particularly including motivational and social factors)2) a Personal Learning and Maturing Environment (PLME), embedded into the working environment, enabling and encouraging the individual to engage in maturing activities3) an Organisational Learning and Maturing Environment (OLME), enabling the organisation to analyze and to take up community activities, to reseed innovation processes and to apply breeding strategies4) reusable Maturing Services for seeding and reseeding, and creating awareness of relevant activities<br/>
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Hybrid atom-ion Quantum Systems'.

assistant: **Objectives**

This project focusses on realizing and studying a new hybrid ultra-cold atom-ion system for studying quantum many-body physics. It combines state-of-the-art technologies in quantum optics and quantum gases. The proposed system of cold (fermionic) atoms interacting with ion crystals has surprising  analogies  with  natural  solid  state  systems  and  molecules,  with  now  by fermionic 6Li atoms in place of electrons and heavy  174Yb+  ions in place of ionic cores. In particular, an atomic band structure may arise with tunable atom-phonon interactions. The proposed experimental approach is inspired by advances in pioneering experiments with hybrid atom-ion systems. By using a new atom-ion combination that has the highest experimentally feasible mass ratio of 29 (Li and Yb+), heating due to the dynamical trapping potential of the ions is suppressed. This eliminates an important road block in existing hybrid atom-ion experiments towards reaching deep into the quantum regime. I will use optical micro-traps in conjunction with segmented ion traps to study the system in a regime with a small number of atoms (1-100) and ions. This offers unprecedented control over the quantum states of atoms and ions. Engineering non-classical states in the ions will allow for quantum enhanced measurements of the combined atom-ion system, with single atom and single collision resolution. State-dependence in the atom-ion interactions can be employed to engineer quantum potentials for the atoms, leading to large scale ion-atomic Schrödinger cat-type entanglement.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Single Molecule Mechanisms of Spatio-Temporal Chromatin Architecture' (ChromArch).

assistant: **Concept**

Chromatin packaging into the nucleus of eukaryotic cells is highly sophisticated. It not only serves to condense the genomic content into restricted space, but mainly to encode epigenetic traits ensuring temporally controlled and balanced transcription of genes and coordinated DNA replication and repair. The non-random three-dimensional chromatin architecture including looped structures between genomic control elements relies on the action of architectural proteins. However, despite increasing interest in spatio-temporal chromatin organization, mechanistic details of their contributions are not well understood.With this proposal I aim at unveiling molecular mechanisms of protein–mediated chromatin organization by in vivo single molecule tracking and quantitative super-resolution imaging of architectural proteins using reflected light sheet microscopy (RLSM). I will measure the interaction dynamics, the spatial distribution and the stoichiometry of architectural proteins throughout the nucleus and at specific chromatin loci within single cells. In complement single molecule force spectroscopy experiments using magnetic tweezers (MT), I will study mechanisms of DNA loop formation in vitro by structure-mediating proteins. Integrating these spatio-temporal and mechanical single molecule information, I will in the third sup-project measure the dynamics of relative end-to-end movements and the forces acting within a looped chromatin structure in living cells.Taken together, my experiments will greatly enhance our mechanistic understanding of three-dimensional chromatin architecture and inspire future experiments on its regulatory effects on nuclear functions and potential therapeutic utility upon controlled modification.