RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Surface engineered InGaN heterostructures on N-polar and nonpolar GaN-substrates for green light emitters'.

assistant: **Innovation**

The goal of this project is to develop the potential of molecular beam epitaxy on nearly dislocation free GaN single crystals for semiconductor lasers in the green spectral range (520-550nm). The active structure will consist of In-rich InGaN layers. Our goal is to push the internal quantum efficiencies of green emitting InGaN devices at 520 nm beyond 30% and to obtain stimulated emission beyond 500 nm. This will be done by (i) engineering the active structure of the device to reduce the effects of piezeolectric fields that reduce the efficiency of these devices (ii) exploring molecular beam epitaxy on non-polar, semi polar and N-polar surfaces to obtain maximum In incorporation and by (iii) improving the structural perfection of the active layers by applying surfactants. It must be understood though that there is no fully established know-how, in terms of growth, optical and structural properties of In-rich InGaN/GaN heterostructures Spinodal decomposition, In-segregation and misfit dislocation formation are still major issues. Structural degradation caused by the specific growth conditions necessary for high In-content layers dramatically reduces the internal quantum efficiency. Piezoelectric fields, due to the high strain of In-rich structures contribute to further reduction in efficiency of devices. Realisation of nonpolar or semipolar devices can reduce the piezoelectric fields. However, high levels of In incorporation, a prerequisite for green emitters, is a challenge that has not been solved till now. Our project combines molecular-beam epitaxy with unique dislocation free GaN substrates, advanced structural analysis and state of the art modelling and simulation to overcome these limitations. The project will take full advantage of the know-how acquired at TopGaN
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Get organised our dissemination of die in Europe - network'.

assistant: **Innovation**

- Create a network with an open membership list.- Set up a programme of meetings, seminars, etc. for information exchange.- Give presentations at other conferences, seminars, etc. on KGD information.- Make contacts with other MCM and electronic packaging groups, e.g. EUROPRACTICE-MCM, NETPACK, JESSI, MCC etc.- Issue a newsletter on KGD and associated topics.- Create contacts made with standards groups to maintain continuity.- Exploit the need for KGD and the use of the databases.The current acceleration of MCM development is led by the need in electronics packaging for increased integration, reduced size and weight, increased reliability, reduced cost and increased performance. One of the major factors in MCM design is the use of new technology and very high I/O ICs such as microprocessors and ASICs with many thousands of gates. For memories and other devices, the technology is shrinking to 0.5, 0.35 and even 0.25 micron. The use of these new technologies affects the device yield; the higher the number of die per MCM, the greater the risk of low first time yield and the need to rework. In order that the manufacture of these high density MCM electronic modules be cost-competitive with current electronic manufacturing technology, Known Good Die, KGD sourcing must be possible.If the KGD concept is accepted internationally, it will also reduce the costs of single die packaging due to the higher yield of the die. To assist in achieving these requirements, this project is set up to create an information exchange network open to all semiconductor manufacturers, systems designers, MCM manufacturers and users, CAD vendors, standards organisations, etc. for the exchange of information on KGD. This will be based at a technical organisation who will assist in the organisation of se
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Cytoplasmic terminal polymerases: small molecule opportunities to target the microRNA pathway', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

MicroRNAs (miRNAs) are a novel class of human disease genes that are key to a number of therapeutic areas in particular cancer, and also heart disease, infectious disease and ageing. Specifically, some miRNAs are known to regulate cancer therapeutic targets acting as tumour suppressors and some are prognostic and diagnostic markers of human disease. The requirement for targeted anti-cancer therapies to effect specific disease treatment is well established and considered a primary goal for moving cancer towards a treatable, controllable chronic condition.miRNA-based therapeutics is a well-occupied space.  However, existing commercial efforts and IP is focused on the use of oligonucleotides and oligonucleotide derivatives to inhibit or modulate the expression of miRNAs. Such efforts have been largely limited by the challenges associated with poor delivery.Instead we have identified novel opportunities to target miRNA pathways using small molecules. Specifically, we discovered a novel class of enzymes (TUTases) that regulate miRNAs by terminal polyuridylation. We found that a specific member of this family (Tut4) acts to inhibit the tumour suppressor miRNA let-7 in a model organism and human cancer cells. TUTases likely provide multiple novel anti-cancer targets. For example, the Tutase Gld2 was recently shown to regulate the p53 tumour suppressor pathway by modifying the miR-122 miRNA.We have developed an efficient in vitro assay of Tut4 activity. Here, we want to develop this assay into a high-throughput screening platform to identify small molecule inhibitors of Tutases. Such small molecules are proof-of-concept molecules for a novel anti-cancer strategy.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Emergency response made easy. Expansion to EU.' to be submitted under Horizon 2020.

assistant: **Abstract**

Pilotech has an ambition to expand its Emergency Response business into EU. In order to do this, it needs to gather market knowledge and product requirements in EU. Pilotech is seeking to partly finance a feasibility study covering market intelligence and product insight through SME instrument – phase 1 (€ 50 000 )Our mission: Runaway Tiger, Chemical leakage, Aircraft accident. It is not the fact that you have an operation with risk that matters, but how you handle it if it happens. InCaseIT from Pilotech is an operational crisis management system delivered as a Software as a service (SaaS). It will enable large corporations and smaller businesses to document preparedness, mitigate risk and respond adequately if unwanted incidents should happen. How to approach the international market (EU), where to focus, finance requirements and aligning the value proposition to the customer profiles. These are the key points for the feasibility study. We expect the identified system changes to be within reach as some of our present customers are international corporations. Hence the main learning points will be on the business side of the study. Pilotech has developed InCaseIT and sold InCaseIT to 35 customers covering branches like airlines, chemistry factories, property owners, hotel operators, amusement parks, Red Cross, ship builders mainly in Norway. Given our go to market strategy proves valid, Pilotech will reach a revenue in 2022 of € 7MM (30% profit margin).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'DuoLipo-TNP: Dual-Responsive Liposome Platform for Selective Delivery of Triphosphate Nucleotide Prodrugs in Triple-Negative Breast Cancer' to be submitted under Horizon Europe.

assistant: **Abstract**

Breast cancer is the most frequently diagnosed cancer in women worldwide and a leading cause of cancer mortality in Europe, with triple-negative breast cancer (TNBC) representing the most aggressive and therapy-resistant subtype. Driven by tumor heterogeneity, poor vascularization, and a hostile microenvironment, TNBC urgently requires new therapeutic strategies, an unmet clinical need directly aligned with the EU Mission on Cancer. DuoLipo-TNP seeks to address these challenges by developing dual-responsive liposomal nanocarriers for the selective delivery of γ-masked triphosphate nucleotide prodrugs (TNPs). The platform combines tumor-penetrating iRGD peptides for αvβ3/αvβ5 integrin-mediated vascular targeting with lipid components responsive to hypoxia and acidic pH, two hallmark features of TNBC. This dual-triggered strategy enables site-specific release of active antimetabolites, bypasses kinase-dependent activation, and minimizes systemic toxicity. The project applies a multidisciplinary approach spanning prodrug synthesis, advanced liposomal formulation and characterization, and comprehensive pharmacological validation in 2D and 3D TNBC models, including patient-derived spheroids. Ultimately, DuoLipo-TNP aims to establish a platform for intratumoral delivery of nucleotide analogues, advancing precision nanomedicine and contributing to the EU Mission on Cancer by improving outcomes in drug-resistant solid tumors.


**Keywords:** Triple-negative breast cancer, Triphosphate nucleoside prodrugs, Smart liposome, Drug delivery
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Advanced Cryptography from Lattices' (ACryL) targeting Horizon Europe.

assistant: **Abstract**

As organizations increasingly rely on cloud services and shared infrastructures to store data and delegate resource-intensive computations, it is essential for maintaining privacy, security, and compliance with regulations to i) protect data while ensuring that only authorized individuals or systems can decrypt and use it, and ii) guarantee the correctness of the computation performed by cloud services. Advanced cryptographic primitives tackle both of these challenges: on the one hand, attribute-based encryption (ABE) effectively addresses the problem of selective data sharing while preserving confidentiality of unauthorized messages, on the other hand, succinct arguments (SNARKs) enable end users to verify efficiently that outsourced computation was performed correctly by cloud providers.In recent years, both ABE and SNARKs have seen tremendous research progress, especially in the context of lattice-based cryptography, where both constructions often rely on shared techniques, underscoring the deep synergy between these two cryptographic primitives.Leveraging lattice-based assumption offers several key advantages in this context, which are essential to the proposed project, in particular, enabling the construction of ABE for general circuits, and providing post-quantum security, meaning these constructions are believed to remain secure even in the presence of quantum computers.By exploring and developing new techniques that leverage these synergies, this project aims to advance theory and practice in both domains and construct robust, quantum-secure cryptographic systems that address the complex security and privacy challenges of the digital age.


**Keywords:** cryptography, advanced encryption, proof systems, post-quantum, lattice-based cryptography
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Disappearing Act: Reconstructing the Crime of Disappearances in Times of Political Violence' (DISACT) targeting Horizon Europe.

assistant: **Abstract**

DISACT will investigate the logic of the crime of disappearances in repressive and (post)conflict settings. Even though combatants have always gone missing on the battlefield, the purposeful disappearance of people is a relatively recent phenomenon. Around 1,000 people now disappear daily, with high levels of public attention to the phenomenon, yet we know relatively little about the historical origins of the crime, the rationale for violent (state and non-state) actors to deploy it, or the processes underpinning its international diffusion. In answering these questions, the project will draw on in-depth analysis of six carefully selected cases, each geared towards documenting a different stage or thematic manifestation in the historical evolution of disappearances. First, DISACT will use archival sources to examine how disappearances emerged in the context of the French colonial counterinsurgency in Algeria (1954-1962). It will then draw on rich ethnographic evidence of violence in Cyprus (1955-1974) to shed light on the logic of the crime in conflict settings. Next, DISACT will investigate the hitherto unexplored role of illiberal intergovernmental organizations in facilitating regional diffusion by analysing the Shanghai Cooperation Organization (SCO) in Eurasia (2005-2020). Finally, the project will innovate methodologically by using forensic evidence to uncover the strategic logic of selective removal of remains of victims from original grave sites, comparing the experiences of Cyprus, Chile, and Bosnia. This comparative, interdisciplinary, and multimethod project will blend ethnographic, forensic, legal, and archival evidence to enrich the understanding of one of the most complex human rights violations of our time. Understanding the motives driving disappearances
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Socially-Acceptable and Trustworthy Human-Robot Teaming for Agile Industries' (SOPRANO) under Horizon Europe.

assistant: **Objectives**

Manufacturing, construction, and agriculture are major driving forces for the European economy and prosperity. Maintaining its competitiveness in these sectors demands highly efficient and flexible processes, and this can be achieved through digitization. Novel intelligent robotic capabilities that can be deployed side-by-side with humans and can operate and adapt to dynamic environments can accelerate this process. However, existing robotic systems cannot fit well into such settings as they are not versatile and flexible enough to automate certain tasks, cannot collaborate safely with humans in open and dynamic environments, nor are they easily and economically adaptable to process changes. The SOPRANO project coalesces multidisciplinary research and innovation in human-robot collaboration and intelligent multi-agent systems, aspiring to design the next generation of manufacturing floors, construction sites, and agri-food production, where humans and intelligent machines will seamlessly work together. It proposes to scale collaboration from the single human-agent dyad to a peer-based synergy between multiple interconnected robotic systems featuring different physical and cognitive properties, supporting various tasks in collaboration with human workers, robotics and other agents. SOPRANO will validate the technological offering in three novel and open-access use cases addressing both large-scale industries and small to medium enterprises, adding value to EU key sectors and instrumenting community building surrounding the open-source technologies in the EU industrial ecosystem. During the project, we will also enable external SMEs and start-ups to benefit from the project technologies via an open call, which will enable the building of demonstrators using SOPRANO techno
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Polymer Informatics Tools for Sustainable 3D printing' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Polymer informatics supports sustainable development goals by implementing versatile computational tools which allow users to move the polymer design from the laboratory to the digital world.To connect the links between the structure, properties and performance of the polymer materials, many pieces of puzzle need to be collected over a wide range of time and length scales, starting from the quantum and progressing hierarchically towards continuous methods. Due to their relative novelty, systematic bottom-up approaches for biodegradable polymers are in short supply. Owing to their rich structure stemming from the natural origin, they need to be simulated with a great detail, what leads to an increased computational complexity and researchers’ frustration. Consequently, the computational studies struggle to keep pace with the emerging applications and technologies such as additive manufacturing. PITS3D project aims to speed up the progress in the field by proposing a systematic bottom-up study of two biodegradable polymers widely used in 3D printing techniques. The atomistic description of the local processes of the selected samples represents the first pillar of the approach. In the second stage, the computational study is extended to longer time and length scales, while going beyond the state-of-the-art by mimicking the characteristics of commercially-produced biodegradable polymers. By providing the simulation input files as open-source starting packs, PITS3D aims to encourage the further development of these computational tools. Another objective is to bridge a gap between the theoretically studied systems and those used for the 3D printing, by establishing an iterative passage of properties between the computational and experimental techniques. The combination of bot
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'New modes of governance'.

assistant: **Objectives**

This Integrated Project aims to produce a deeper conceptual, empirical and normative understanding of all aspects of governance within, and beyond, Europe, emphasizing the emergence, execution, evaluation and evolution of new and innovative modes of govern ance. Our pan-European and multi-disciplinary research Consortium engages political scientists, economists, lawyers, sociologists, and practitioners to collect data on,and to map and analyze, innovations in the instruments, modes, and systems of governance operating at the multiple levels and arenas of the evolving and enlarging Euro-polity and economy. Of particular interest are the ways in which these innovative mechanisms and practices relate to each other (both horizontally and vertically);how they rela te to 'old methods' of governance;and the implications they hold both for the effectiveness and efficiency of policy making, and for the normative and democratic nature (accountability, participation and citizenship - and thus legitimacy) of the European U nion. In terms of instruments and modes of governance, we investigate new forms of multi-level partnership, deliberation and networks, as well as innovations in systems of socio-economic governance, producing new knowledge on their emergence and developmen t in different policy sectors and arenas;how their implementation and use differ across existing and future Member States; and how they are articulated at the local, regional, national, European, and global levels. Ethical and gender issues are addressed w here relevant. Thus the NEWGOV Consortium contributes to the creation of a European Research Area in the social sciences and humanities by shaping a new European-level research agenda;by integrating previously dispersed researchers within a coherent, pan-E ur
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Optimilizing public understanding of science and technology in europe' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The pervasiveness of science and technology's influence in every aspect of modern life implies a necessity for citizens to understand and appreciate the contributions, but also the limits, of what research and technological development can/should provide for human society and the natural environment. However, there seems to be a general lack of public awareness of European-level research activities and their impact on the economy, the quality of life, employment and environment. The OPUS thematic network which brings together leading experts and practitioners in field of Public Understanding of Science aims at reviewing the different national practices/activities to raise public awareness, at comparing them in order to understand the influence of particular contexts and at studying the transferability of best practice initiatives across national boundaries and to the European level. The result will be policy recommendations for improving public visibility of science and technology in Europe as well as a Handbook bringing together both theoretical synthesis of discussions and the empirical material.