RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Modelling and simulation environment for systems medicine\n(Chronic obstructive pulmonary disease -COPD- as a use case)' (SYNERGY-COPD) targeting Seventh Framework.

assistant: **Abstract**

Synergy will develop a simulation environment and a decision-support system aiming at enabling deployment of systems medicine. The three core elements are a knowledge base (KB), an inference engine (IE), and a graphical visualisation environment (GVE). The project focuses on patients with chronic obstructive pulmonary disease (COPD).<br/>The KB will include five well established physiological models addressing: 1) Central and peripheral O2 transport and utilization, 2) Pulmonary gas exchange, 3) Regional-lung heterogeneities in ventilation and perfusion, 4) Skeletal muscle bioenergetics, and 5) Mitochondrial reactive oxygen species (ROS) generation. These models will be written in systems biology markup language (SBML) and vertically integrated. Ontologies will be used as the default knowledge-representation system. The KB will include multi-level data from experimental studies (BioBridge), data from a multicentre longitudinal study on COPD phenotyping (PAC-COPD) and public datasets.<br/>The IE will enable to explore associations over the KB, perform transversal multi-scale model integration and related simulations including interactions among O2-availability/O2-utilization, ROS generation, systemic inflammation and abnormal tissue remodelling.<br/>The Web-based GVE will facilitate relevant simulations in a more intuitive way with respect to the state of the art, addressing two main user profiles: bio-researchers and clinicians.The focus will be on underlying mechanisms of COPD phenotypes associated with poor prognosis. Disease model validation and refinement will be done using a well-established, large dataset (ECLIPSE) together with experimental studies designed to test in silico" generated hypotheses. Besides the use of the simulation environment by bio-researchers f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Nanostructured Photoelectrodes for Energy Conversion' in the context of a Seventh Framework call.

assistant: **Objectives**

To address the challenges of photon capture and energy conversion, we will investigate solar-driven hydrogen production via photoelectrochemical water splitting.  Although the concept is extremely attractive as a method of sustainable fuel production, no single material with acceptable performance, stability, and cost has been found, despite decades of investigation.  To address this significant challenge, we will use new concepts and methods, afforded by nanotechnology, to design innovative composite nanostructures in which each component performs specialized functions.  These novel nanocomposites will decrease the number of criteria that any single component must meet, thus overcoming the basic materials limitations that have hindered development.  Computational studies will be used to assist in the selection of optimal material pairings and a wealth of advanced analytical techniques will be employed to improve the understanding of structure-composition-property relationships.  As a final objective, we will use NanoPEC’s innovations to develop a 1 square-centimeter test device that converts solar energy to hydrogen energy with a sustained 10% efficiency and a maximum performance decay of 10% over the first 5,000 hours of operation and a 100 square-centimeter test device with a sustained 7% efficiency and similar stability, representing a performance standard that goes well beyond the state-of-the-art.  NanoPEC’s innovative research will redefine the field of photoelectrochemistry and place Europe at the forefront of nanoscience and nanotechnology research by contributing to leadership in this strategically important area.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Innovative Software Configurator for the Insurance sector' (2014-2020) under Horizon 2020.

assistant: **Objectives**

Insurance companies are locked into old complex technology. The insurance market has been disrupted by new technologies, devices and infra-structures that create new products, like usage based insurance, new distribution models like Internet aggregators and new interactions with customers through mobile devices. The insurance industry needs to rid itself of the legacy platform problem, but this is neither easy nor fast, and increasingly alternative solutions that leap frog the problem are gaining traction such as modernizing the peripheral applications around existing systems. While this approach provides a fast solution to pressing commercial problems it does not address the residual risk: that one day the core system, a burning platform, must be replaced. The i2S solution presents a disruptive approach to this problem that is to address change in two stages: first extracting from the existing system the key core knowledge about insurance products, commercial structures, process configuration while core systems and experts that know them are available; and second, having made this knowledge independent of core system, it can now be applied to any new solution or used to keep the existing solution working with a lower risk, even when the original builders are no longer around. This solution is the i2S Insurance Configurator (i2S-IC), an innovative one stop shop for configuration, allowing safe, quick, centralized, consistent and guided configuration, strategically enabling the capture and reuse of the business knowledge that is at the core of any insurance company.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'GATE2BRAIN TOWARDS SME DESIGNATION AND PAEDIATRIC INVESTIGATIONAL PLAN' (G2B-002) targeting Horizon Europe.

assistant: **Abstract**

Gate2Brain (G2B) is a biotech company focused on the development of therapeutics that efficiently cross biological barriers such as the blood-brain barrier (BBB). Using this radically innovative peptide-based patented technology platform, G2B has developed a novel therapy, G2B-002, for pediatric brain tumors such as Diffuse Intrinsic Pontine Glioma (DIPG) and Glioblastoma, currently without a cure or poor prognosis. Small and medium-size enterprises (SMEs) represent 99% of all business in the EU. G2B will apply to obtain SME designation to have access to finance and EU support programs which include research, competitiveness, and innovation funding. Another potential benefit that G2B could obtain is the fewer requirements or reduced fees for EU administrative compliance. G2B is mainly focused on pediatric brain cancer, a rare but mostly lethal Central Nervous System disease. After obtaining SME designation, G2B will develop the Paediatric Investigational Plan (PIP) included in the EU Paediatric Regulation. Thus, G2B expects also to benefit from: (i) reduction of registration taxes; (ii) tax deductions; (iii) access to financial support; (iv) assistance in the drafting of clinical trial protocols; (v) ease of access to procedures to accelerate marketing in Europe; (vi) right to marketing exclusivity for 10 years in Europe; and (vii) 6-month extension patent protection initiative of medicines for children.The Health Economics & Market Access Outcomes Strategy that G2B will also perform will include a willingness-to-pay and product-market fit analysis, between others. The final report will help to estimate the economic value of the company considering relevant alternatives for both the healthcare system and pharmaceutical industry.The R&D strategy of G2B is focused on the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'High Magnetic Field Investigation of Transport and Thermodynamic Properties of Metallic Oxide Hetrointerfaces' in the context of a Seventh Framework call.

assistant: **Objectives**

Artificial, layered heterostructures of transition metal oxides provide an opportunity to tune and couple electronic charge and spin properties on an atomic scale. Strong correlations between electrons can then lead to the formation of exotic new phases at the interfaces which are impossible to stabilise in the bulk materials. This proposal describes an experimental project to investigate the LaAlO3-SrTiO3 heterostructure, where a 2-D electron gas (2DEG) is formed at the LaO:TiO2 interface. The project will employ state of the art magnetotransport and magnetometry techniques in high magnetic fields, at low temperatures and at high pressure. By tuning these thermodynamic parameters we will be able to map a comprehensive phase diagram for the interface, and determine many important aspects of the 2DEG behaviour. Further measurement as a function of sample orientation in a magnetic field will allow us to examine the extent and influence of 2-dimensionality in this system, and by varying the sample growth conditions we will study the effects of disorder, and the relevance of the surface to the properties of the interface.  Our measurements aim to fully characterise the magnetic and conducting properties of the metallic interface in the LaAlO3-SrTiO3 heterostructure, provide new insight into why and how these remarkable interface phases arise, and identify promising directions for the growth of new structures of fundamental and technological interest. The project will involve collaboration between the Nijmegen High Field Magnet Laboratory (HFML), MESA+ at the University of Twente, and the Physics Department of the University of Toronto. As work proceeds, some advancement and development of measurement techniques and procedures will be necessary. This will extend the capabili
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'International accident dosimetry intercomparison exercise at silene' (INTERCOMPSILENE) under Fifth Framework.

assistant: **Objectives**

The OECD NEA and IPSN have agreed to jointly organize, from 10 to 21 June 2002,an international accident dosimetry inter-comparison exercise, using a unique facility of this type in Europe: the IPSN research reactor SILENE.The main objectives are:a) to validate the performance of accident dosimetry systems through controlled irradiation in a characterised mixed neutron and gamma rays field andb) to provide the opportunity to validate criticality and particle transport codes used, for example, to assess the dose in the case of an accident and to size facility shields.The SILENE facility is an experimental reactor built by the IPSN at Valduc, France. It was designed for criticality accidents studies (physics and radiobiology). Runs using 3 different configurations (various neutrons spectra and gamma/neutron ratios) are proposed for the two-week-inter-comparison, furthermore, 2 weeks are needed for the preparation. More than 50 laboratories plan to participate to this inter-comparison.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Therapeutic Applications of Light-Regulated Drugs'.

assistant: **Concept**

One of the major drawbacks of pharmacological therapies is the difficulty to control drug kinetics and restrict drug action to the target organ. This in turn limits the efficacy of drugs and triggers undesired side effects for patients. We have developed an innovative approach to control the activity of drugs with light in cell culture systems. The PoC grant will allow going a step further by testing these new methods on important pharmacological target receptors and assay them in vivo. These tests should lead to the first clinical trials and to present the biomedical applications of his project to pharmaceutical companies. The combination of drugs with external illumination devices could create a more personalised medicine where therapies could be tuned to adapt each individual patient.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Migration of Image Generation and Registration Authoring Tools to the Open Resources of JPEG2000', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

Interoperability and the goals defined by the European Commission make it essential that content creation Authoring Tools comply with the new standards. For still pictures, JPEG 2000 will be soon adopted to replace the popular current JPEG. Its new features reflect the most recent user's requirements.MIGRATOR 2000 addresses image bank content creation, in terms of management and personalisation, taking advantage of JPEG 2000 functionalities, with a new line of Authoring Tools - new compression algorithm based on wavelets - image resolution and/or quality scalability - static and dynamic region of interest coding and decoding - error resilience method for wireless transmission - content protection through registration and watermarking.Objectives:The objectives of MIGRATOR 2000 are many, but the convergence is toward defining and developing all the tools that integrators need to build applications. Each of the JPEG 2000 new functionalities need new software modules and user interface: such is the case for ROI, the access to Region Of Interest, which can address both the user when deciding on a detail to be displayed (e.g. art work examination) or the creator of the digital image who wants to put the emphasis on certain areas in the image (e.g. medical applications).While keeping in mind the necessary protection of IPR, MIGRATOR 2000 aims at the largest dissemination of contents of the created image banks, through the internet for example. Metadata, the associated data to the image, will also be classified and registered together with the essence", which is the image data, into a single file format.Work description:The MIGRATOR 2000 consortium is made of major actors in the definition and the development of JPEG 2000, bringing a background of many years of experience in de
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Sustainable Chemical Alternatives for Re-use in the Circular Economy' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

This proposal seeks to develop a novel non-invasive, real-time direct observation methodology to provide new knowledge on the mechanisms underpinning crystal growth and harvesting within membrane crystallisation reactor technology. Crystallisation represents one of the most important separation processes in the chemical industry and will play a critical role in the circular economy through enabling the recovery of resources from wastewater to yield an array of sustainable low cost chemicals for use in European industries. Existing crystallisation reactor designs suffer from imperfect mixing and inhomogeneous solvent removal which makes control of crystal quality and consistency problematic and can limit application of the final product. Membrane crystallisation reactor technology is a disruptive innovation that combines process intensification with the capability to achieve significant control over the crystallisation process at a fraction of the scale thus ameliorating many of the problems associated with existing crystallisers. However, before this disruptive membrane based technology can be realised at full scale, there is a critical need to understand the role of shear forces in mediating the growth and harvesting of crystals at the solvent-membrane boundary which has to date received little attention. With no reliable and accurate description of the shear force behaviour within the boundary layer, there is considerable risk incurred in the scaling up of membrane crystallisation reactor design which could lead to inconsistent and inefficient performance. Development of the novel non-invasive, real-time direct observation methodology will enable direct measurement of these discrete forces. The arising new knowledge will be challenged at various process sizes to evolv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The application of laser, thermal imaging and infrared technologies to the on-line monitoring and control of industrial freeze-drying processes.' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

A long-standing problem in freeze-drying is the inability to monitor the process quantitatively and reproducibly, and in the determination of the end-point of drying for any given product. Processing conditions have historically been arrived at on an arbitrary basis due to a widespread lack of understanding in the user industries (including pharmaceutical, biotech, vaccines, diagnostics, foods) about the process itself. The partners propose the development of an intelligent process monitoring and control system based on the use of laser-, thermal imaging- and infrared-technologies to provide sensor devices that can be integrated into freeze-drying apparatus. This will enable the process to be more precisely monitored, and controlled on-line on the basis of the information gained. Success of the proposed RTD project will result in significant economic and environmental benefits throughout the EU.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Create a Symbiosis where PV and agriculture can have a mutually beneficial relationship', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The decarbonisation of the energy sector is one of the top priorities at various political levels including at the European level. Photovoltaics (PV) is widely seen as one of the key technologies to drive the energy transition. The difficulties arise when the targets for PV (usually set at national level) needs to be put into practice at regional / local level. Although the PV rooftop potential is extremely large and could potentially contribute to the ambitious targets, the rate of installation of PV rooftop systems will not be fast enough to support a rapid transition. On the other hand, large utility-scale PV installations in open fields are not an option in many regions. It is in this context that the concept of Agrivoltaics is emerging. What several decades of efforts developing Building Integrated PV (BIPV) products and systems for rooftops and facades have taught us is that there are multiple levels of integration and various stakeholders across the value chain which can all generate significant barriers to widespread adoption . Agrivoltaics is in fact in the unique position to learn from the past mistakes made with BIPV which delayed the development of cost-effective BIPV solutions and market acceptance. In SYMBIOSYST we will not develop solutions that are highly customized as this would drive the costs up. We will rather innovate by adapting standardized cost-effective solutions in terms of PV modules, mounting structures and Operation and Maintenance (O&M) practices to the specific needs of various crops in different climates and landscapes. We will also find aesthetically pleasing solutions that can be mass manufactured and integrated with the agricultural land in a harmonious way while maintaining the primary goal of farming. The interdisciplinary consortium