RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Sustainable exploitation and management of living marine resources: a holistic approach' under Fifth Framework.

assistant: **Concept**

Training is offered in a broad range of skills in fisheries and fishery biology, aquaculture and fish diseases, marine ecology and environmental science. The emphasis is on a holistic approach, drawing on local expertise in the biological and physical sciences, economics statistics and social sciences.Training programmes tailored to individual needs are offered, including training in specialised research skills and access to a range of taught courses within a thriving postgraduate school. The host research groups based at the University of Aberdeen and Marine Laboratory Aberdeen have strong track records in research and in research training and are active in many European collaborative research programmes.Specialised facilities available include well-equipped laboratories. For studies in molecular genetics, immunology and diseases, growth and nutrition of marine animals, electron microscopy and a full range of computing facilities.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'MOdel-Driven Approach for design and execution of applications on multiple Clouds', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Current Cloud's offer is becoming day by day wider providing a vibrant technical environment, where SMEs can create innovative solutions and evolve their services. Cloud promises cheap and flexible services to end-users at a much larger scale than before. However, Cloud business models and technologies are still in their initial hype and characterized by critical early stage issues, which pose specific challenges and require advanced software engineering methods.The main goal of MODAClouds is to provide methods, a decision support system, an open source IDE and run-time environment for the high-level design, early prototyping, semi-automatic code generation, and automatic deployment of applications on multi-Clouds with guaranteed QoS.Model-driven development combined with novel model-driven risk analysis and quality prediction will enable developers to specify Cloud-provider independent models enriched with quality parameters, implement these, perform quality prediction, monitor applications at run-time and optimize them based on the feedback, thus filling the gap between design and run-time. Additionally, MODAClouds provides techniques for data mapping and synchronization among multiple Clouds.MODAClouds innovations thus are: (i)simplify Cloud provider selection favoring the emergence of European Clouds, (ii) avoid vendor lock-in problems supporting the development of Cloud enabled Future Internet applications, (iii) provide quality assurance during the application life-cycle and support migration from Cloud to Cloud when needed.The research is multi-disciplinary and will be grounded on expertise from several research areas. MODAClouds consortium consists of highly recognized Universities and research institutions that will assure a sound scientific progress, SME partn
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Sistema basico para patronaje de calzado'.

assistant: **Objectives**

The objective of SIPECO is promote best practice in IT use related to product design and manufacture in small companies in the footwear sector.The main aims of SIPECO are to, - Improve the level of use of IT in the consortium and to demonstrate the advantages of these technologies in the whole sector; - Assess IT needs of footwear SMEs, proposing action towards business improvement through advanced technologies; - Apply a new system of pattern design and manufacturing in order to increase the competitiveness and productivity of the companies; - Improve time-to-market of companies that today work in a very traditional way by the use of IT. This is a critical factor in an industrial sector that is very fashion oriented and whose success depends in many cases on supplying products within heavy time constraints. The expected results and benefits are as follows, - Ten installed systems; - New applied operational procedure for design, manufacturing, costing, sampling, management; - Documentation regarding best practice; - Seminars and courses; - Improvement in time of launching new models (expected 45%); - Economic savings in pattern development and manufacturing (expected 30%); - Increased consolidation in employment (expected 1 labour post per company); - Improvement in employee skills.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Transatlantic crossroads Lab'.

assistant: **Objectives**

TransatlanticLab reexamines colonial and post-colonial interactions within the transatlantic space, using the Atlantic as a historical laboratory to explore colonial domination and racialist ideologies. The project focuses on how these dynamics, emerging from the plantation economy in the greater Caribbean, were maximised on both sides of the ocean. It addresses how race was constructed through economic practices, becoming an instrument of social oppression embedded in thought and language. Beyond traditional European mechanisms like slavery, forced labour, and racialism, the analysis includes their impacts on European territories. It rethinks colonial regimes, historicises European domination languages, and examines intermediaries' roles in maintaining colonial power. TransatlanticLab aims to surpass current decolonial theories and simplistic understandings of racism as merely a system of prejudiced morality that can be corrected through education. The hypothesis posits that racialism and racism evolved tied to the plantation economy, flourishing in the Americas and the Caribbean, and later used in European colonialism in Africa. Our argument is multifold: 1-Colonialism roots in Africa and racism link to Americas' plantation systems. 2-Enslavement created ""Black"" and ""White"" hierarchical systems. 3-Pseudo-scientific racialism naturalised this system. 4-This ideology supported European racist politics by the ""Scramble for Africa."" 5-African colonialism depended on Caribbean plantation economies. 6-European scientific exploration and tropical determinism led to environmental racism. TransatlanticLab will provide new insights into the long-term transformations of the tools of imperialism and colonialism. In order to comprehend the impact of these instruments of powe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Hyaluronic acid as a potential mediator of the inflammatory responses associated with atherosclerosis'.

assistant: **Innovation**

The processes involved in the formation of atherosclerotic lesions include: i) the proliferation of vascular smooth muscle cells (VSMC), macrophages and possibly Iymphocytes; ii) the formation by VSMC of a connective tissue matrix comprising elastic fibre proteins, collagen and proteoglycans; and iii) the accumulation of lipid and mostly free and esterified cholesterol in the surrounding matrix and the associated cells. Among several growth factors and cytokines platelet-derived growth factor (PDGF) has been shown to be essentially involved in atherosclerosis. It is generally not expressed in the normal artery, whereas it is upregulated in lesions of atherosclerosis. We have recently shown that PDGF stimulates human VSMC, in culture, to secrete a specific form of hyaluronic acid (HA), with molecular mass of 340 kDa, which has a potent antiproliferative activity on VSMC. These results suggest that VSMC in response to PDGF are capable of controlling their own growth by the synthesis of this specific 340-kDa HA molecule which may be involved in the regulation of the local inflammatory processes associated with atherosclerosis. In the present study we are going to investigate: a) The molecular mechanism by which the 340-kDa HA inhibits VSMC proliferation. b) The effect of the 340kDa HA on VSMC migration and c) The presence of this molecule in the different layers of human atheromatic arterial walls as compared with normal arteries. Such information will highlight a further fascinating facet of the complex regulatory network controlling VSMC growth and migration in vessels and will have farreaching implications for our understanding of the pathophysiological mechanisms contributing to the formation of atherosclerotic lesions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'How the human thalamus guides navigation and memory: a common coding framework built on direct thalamic recordings' (DirectThalamus).

assistant: **Innovation**

The thalamus is the major gateway for sensory input to the brain, and, as such, has long been thought of as a mere sensory relay station. But accumulating evidence suggests that it is crucially involved in higher cognitive functions like memory formation and navigation. However, methodological obstacles still impede full understanding of the specific role of thalamus in human cognition.The core objective of DirectThalamus is to provide an advanced oscillatory model of subcortical processing as the neuronal basis of core cognitive functions. To this end, the project will address several key questions with the aim to identify and understand neuronal processing in the thalamus involved in human cognition: How does the human thalamus code and communicate information? And how does this contribute to spatial navigation and the formation and consolidation of memories?Using my unique expertise in innovative methodologies, I will exploit the rare opportunity to record and modulate intracranial electrophysiological activity in the human anterior thalamus. Together with intracranial recordings from the human hippocampus and comparative fMRI data from healthy subjects, these data will be used to test and establish a common coding framework for memory and navigation, highlighting contextual information processing as fundamental thalamic function.By directly recording and stimulating intracranial thalamic activity, DirectThalamus will provide novel and causal insight into thalamic mechanisms underlying core cognitive functions. The project will thereby push the boundaries of the state of the art in cognitive neuroscience towards a comprehensive understanding of cognition. Expanding the prevalent corticocentric focus on cognition to subcortical contributions will inspire new lines of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Solar Thermochemical Compact Storage System' in the context of a Seventh Framework call.

assistant: **Objectives**

SoTherCo’s major objective is to install, monitor and assess an innovative modular, compact and seasonal thermo-chemical solar heat-storage system, namely the SoTherCo HSS (Heat-Storage System). The modular design, based on the proper arrangement of ~1000L heat-storage modules, is intended to offer the needed flexibility and adaptation to answer the space-heating demand of low-energy buildings, from a single family dwelling up to communities and district heating.The Demonstration WP5&WP6 will be performed semi-virtually over long periods of time and at two different locations i.e. Arlon (ULg-Belgium) and Bourget-du-Lac (CEA-INES, France)) for regional climatic particularities. The testing periods will be shifted in time (6 months) for permitting to integrate the learning from the first demonstrator into the other one.To this end, RTD activities are also scheduled according to a progressive and controlled integration of the best-in-class knowledge and improvements in the field.WP1 will select and optimize at least 3 thermo-chemical working pairs referred to as SMG (Salt-in-Matrix composites + water-vapour (G)).WP2 will test the SMGs performance in laboratory-scale heat-storage units (the mini-Modules, m-M) operating in simulated real-life conditions. At least 3 m-M will be designed, modelled, constructed, tested and iteratively improved with respect to each of the selected SMGsWP3 will up-size (model, build and test) several real-scale (rs-M) to understand their complete behaviour in terms of power response and energy balance.WP4 will design, model and engineer the complete Heat-Storage Systems (HSS) comprising several properly connected rs-M as well as all the needed additional devices (energy inlets outlets, pumps, control, ..) ready to be integrated at the demonstrati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Biomimetic Lipid Structures on Nano- and Microfluidic Platforms', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The projects aim at the formation, manipulation, and analysis of three-dimensional lipid membrane structures on micro- and nano-structured platforms. The goal is to develop a novel methodology to design and create simple artificial cells and cell organelles, bio-hybrid cells, and bio-mimicking membrane networks, which could be an entirely novel tool for cell analysis, and promises fascinating prospects for cell manipulation, biotechnology, pharmacy and material sciences. The basis of the projects is formed by an unconventional concept that involves two current cutting-edge fabrication technologies, i.e. the so-called top-down and bottom-up approaches. The combination of the two approaches, with respect to both engineering methods and biological applications, opens the door to overcome current limitations in the creation of complex soft matter objects in micro- and nanometre dimension. The key method is a recently developed micro-extrusion process. It relies, on the one hand, on the ability of the lipid molecules to self-assemble (“bottom-up”). On the other hand, photolithography processes (“top-down”) are utilized to fabricate microchips, in which shape transformation, handling and analysis of the lipid structures are performed. The proposed engineering process will enable, for the first time, to precisely design composition, size and morphology of complex membrane structures. It will provide the requirements to design an artificial cell of reasonable complexity (“bottom-up”). One main emphasis is the creation of unique bio-hybrid systems, in which artificial membrane structures are connected to living cells, or in which natural membranes of cells are integrated within artificial systems (“top-down”). This highly interdisciplinary study will further include fundamental
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Innovative nanoparticle formulation for a miR-133 based treatment of cardiac hypertrophy' in the context of a Horizon 2020 call.

assistant: **Objectives**

Innovative nanoparticle formulation for a miR-133 based treatment of cardiac hypertrophyCardiovascular diseases (CDs) are growing problems worldwide, affecting as much as 1% of the population. The causes include ischemic, toxic, genetic, post-inflammatory and structural defects; often multiple etiologies are present within an individual patient germane to the contraction failing, resulting in a mortality of ca. 50% within 5 years from diagnosis. Unexpected roles have been unveiled for microRNAs, important key-players in such pathogenesis, able to regulate levels of genes that govern cell remodeling. In line with this, development of microRNA-based drugs aimed at preventing stress-induced dysregulations of microRNA levels has attracted remarkable attention as potential candidates for therapeutic applications. Particular attention is paid to the miR-133, a muscle-specific microRNA, which has been found inversely related to pathological cardiac hypertrophy. However, a key challenge of microRNA-based drugs relies on delivery efficiency, toxicity and specificity. Here, we propose to generate innovative and effective therapeutic strategies based on the development of novel biocompatible and bioresorbable calcium phosphate nanoparticles (CaP-NP) for carrying miR-133 selectively to the heart. Our aim is to functionalize CaP-NPs for a selective delivery of the therapeutic miR133 to the pathological heart. The development of a novel approach based on CaP-NPs might be an efficient cardiac drug-delivery system for a specific release of miR-133. The successful outcome of this proposal will provide a relevant preclinical proof-of-concept necessary for 1) the development of additional Intellectual Properties, 2) the translation into a commercial strategy and business case, and 3) the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Cohort Network To be Activated Globally In Outbreaks'.

assistant: **Innovation**

CONTAGIO is a consortium of investigators from Europe, North America, Latin America, Asia, and Africa, that aims to create coordination mechanisms to rapidly react to infectious disease (re-)emergence in low- and middle-income countries (LMICs). The Consortium builds on the experience acquired through the EC-funded projects ReCoDiD, ORCHESTRA, ZIKAlliance, and IDAMS.We believe that observational cohorts are essential instruments as they provide much needed information on the natural history of the disease, including transmission routes, vulnerability factors, the proportion of, and risk factors for, severe disease outcomes and therefore lay the ground for intervention studies.CONTAGIO will convene cohort investigators and data/specimen sharing specialists by a) generating a preparedness and interoperability platform (WP1/2); b) enabling a suite of tools and key pathways for data sharing (WP2/3); and c) developing governance for sharing of biological material in the event of emerging infections (WP4). A key step on this path is the investigation of how ongoing cohorts ‘repurpose’ their focus from one infectious disease to another in the event of epidemics (e.g. from dengue to Zika to COVID-19). The open science foreseen in CONTAGIO will create a coordination mechanism and framework for the role of sustainable cohorts in preparedness for (re-)emerging infectious diseases during interepidemic periods, which will be vital for the joint progress towards a better tackling of disease emergence aimed at the protection of citizens in LMICs, Europe and the rest of the world.


**Keywords:** Preparedness, Harmonization, Data sharing, Biorepository
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'The Afterlives of Development Interventions in Eastern Africa (Kenya, Tanzania, Mozambique)'.

assistant: **Concept**

International development involves ideologies and activities ostensibly directed towards the improvement of well-being of populations in the Global South. Mainstream development interventions emphasize forward-looking ideas of progress and advocate for novelty. In so doing, however, the sector is often myopic, as evidenced by countless unintended consequences that stretch beyond interventions' official life cycle. Whether deemed success or failure, such interventions leave behind a long trail of tangible and intangible traces.Project AfDevLives explores how development interventions' representational and material remains are experienced, employed, and re-appropriated by local actors over time, and how such active immanence of the past affects people's life-worlds. It weaves together three temporal gazes: prospective (development's blueprints); retrospective (sediments of the past, shorthanded as interventions' 'afterlives'); and present-time lived experience. Consciously de-centering formal development discourse and temporalities, the project develops and applies a phenomenological framework oriented around embodiment and intertwinement of people, objects, and space.Using an interdisciplinary approach centered on social anthropology, research will be conducted in Kenya, Tanzania, and Mozambique, neighbouring Eastern African countries that are among the highest recipients of development aid and whose past and present balance continuities and ruptures. The project will unfold via an iterative process involving four complementary work packages: Movement, Image, Storytelling, and Synthesis. Working across work packages, countries, and case studies, the project will pursue three categories of objectives: conceptual (methodological toolkit), empirical (based on extensive ethn