RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Local solutions for future challenges: Community Owned Best practice for sustainable Resource Adaptive management in the Guiana Shield, South America'.

assistant: **Innovation**

Novel funding initiatives are on the cusp of implementation across the developing world. Community owned solutions for the management of ecosystem services have the potential to act as showcases for determining the most effective and efficient use of these emerging funding streams in order to maximise social justice and ecological sustainability. The COBRA project brings together key South American and European CSOs that have extensive experience in enabling and disseminating grassroots solutions to complex problems in the Guiana Shield region of Brazil, Colombia, Venezuela, Guyana, Suriname and French Guiana. The RTDs on the project have scientific expertise to rigorously evaluate these grassroots solutions and determine their impact, while the SME brings with it the business and technical expertise for promoting the financial viability of these initiatives. The CSOs, RTDs and the SME have formed a partnership to help deliver effective community-led sustainable management of ecosystem services and to widely disseminate best practice. We therefore aim to: 1) review the emergence of novel social, economic and environmental challenges facing communities in the Guiana Shield region; 2) engage with established locally owned and developed solutions; 3) analyse and record these solutions in order to investigate their generic transferability; 4) test the approach in a wider range of communities confronting similar challenges; 5) facilitate communication between communities and governments to ensure local needs are addressed and emerging policies benefit local communities; and 6) develop a range of accessible communication and dissemination tools for engaging a wider global constituency. The COBRA project will be in a unique position to study the impact of new funding streams o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Making Sense of Metagenomes'.

assistant: **Innovation**

Microorganisms are the greatest chemists of our planet. Almost every chemical reaction that is thermodynamically feasible is exploited by these organisms to sustain growth and survival. Together, the actions of microbes comprise the biogeochemical element cycles, a vastly complicated metabolic network that is the basis of all life. Since a few years the metagenomic exploration of this network has begun. Ten years from now next-generation massive parallel sequencing technology will enable the cost-effective near-complete molecular characterization of microbial communities. This development has great applied and fundamental potential. So far metagenomes were recorded for natural communities with poorly characterized natural history. Consequently, such metagenomes are very difficult to interpret. To move forward, it is essential to record metagenomes of microbial communities at precisely defined selective pressure. That is the key innovation of my ERC application. It is a simple step forwards, and a very challenging one. It will require a combination of skills in engineering, biochemistry, microbial ecology, physiology and bioinformatics. This combination is exactly what has propelled my previous research. My project focuses on communities involved in nitrate respiration. The turnover of nitrate plays a key role in all geochemical element cycling while its natural abundance is severely affected by human activity. The environmental fate of nitrate is currently unpredictable. My project will deliver fundamental molecular understanding over the workings of natural selection for nitrate respiring communities. It will express this understanding into useful, general metagenomic markers. This is a pioneering effort; it will serve as an example to the field and show how to capital
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Coupled Dynamics and Vibration Control in Integrated Floating Wind and Wave Energy Structures' under Horizon Europe.

assistant: **Concept**

This project focuses on integrating floating offshore wind turbines (FOWT) with wave energy converters (WEC) to simultaneously harness offshore wind and wave energy. The specific objectives are: (1) to gain an understanding of the interactions between the FOWT, WEC, and surrounding flow fields, and to explore the nonlinear vibrations of the FOWT-WEC system; (2) to thoroughly assess the serviceability and safety performances of the FOWT-WEC system under both operational and extreme conditions; and (3) to develop innovative vibration control techniques aimed at effectively reducing responses of the FOWT-WEC system.To achieve these objectives, a multi-body model will be developed and integrated with aerodynamics, hydrodynamics, and structural dynamics computational modules to simulate the coupled dynamics of the FOWT-WEC system. Optimal designs for the WECs in terms of numbers, shapes, and configurations will be conducted to maximize energy generation and reduce wave loads, with a thorough evaluation of the system’s serviceability and safety. Given the space constraints and changes in structural dynamic characteristics, a novel pendulum inerter-based nonlinear energy sink will be designed to mitigate excessive vibrations within the FOWT-WEC system. The project will also incorporate comprehensive outreach and educational initiatives, including tutorials in STEM courses, engaging graduate and undergraduate students in research, and offering seminars and webinars to stakeholders.The research outcomes will contribute significantly to the creation of a new integrated wind and wave energy harvesting paradigm with the consequent reduction of energy costs on both national and global levels. This fellowship will provide substantial support in achieving the researcher’s future acade
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Macaronesia’s Researchers' Night', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Macaronesia is a biogeographical region of five archipelagos in the Atlantic Ocean of which four are inhabited: Azores (Portugal), Canarias (Spain), Madeira (Portugal) and Cape Verde (Cape Verde). These islands share common geographical traits and cultural heritage, and have undergone a similar history since the beginning of the 15th century when they were discovered by Portuguese and Spanish sailors. Once major strategic outposts now they are considered as outermost (ultra-peripherical) regions of the EU (except Cape Verde, which declared its independence from Portugal in 1975). The population of Macaronesia is around 3 million inhabitants, corresponding to the size of a smaller EU country. The overall objective of this project is to organise a shared Researchers’ Night for the Macaronesia Region connecting the population of these islands under the umbrella of the universal language of science. By focusing on the scientific and technology areas identified in the Smart Specialization Strategies for the Canaries, Madeira and the Azores we will aim at raising public awareness for research areas that could be the greatest benefit for the Region. The project will support the public recognition of researchers, creating an understanding of the impact of researchers' work on citizen's daily life. Public recognition will then result in public support that is much needed for the implementation of the smart specialisation strategies themselves.


**Keywords:** Researchers' Night, Outermost Regions, Smart Specialization Strategies
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Mobility and management of cattle in Iron Age and Roman Netherlands' (MoMa).

assistant: **Concept**

This research project aims to study long-term developments in cattle management and mobility in the Netherlands, from the Iron Age to the Roman period (750 BC – AD 450). Cattle have always played a crucial role in this region, in supporting arable farming by traction and manure, in providing food in the form of meat and dairy products, and in providing raw materials for clothing and artefacts. Our understanding of cattle management could be improved enormously by an integrated study of traditional and newer methods of research. The main objectives of the research project are:•to investigate movements of cattle in the Iron Age, indicating exchange and/or raiding;•to investigate movements of cattle in the Roman period, indicating import and/or local supply;•to investigate whether the size increase of cattle in the Roman period was a direct result of the incorporation in the Empire, or whether it should be seen as a continuation of developments that started in the Iron Age;•to provide a comprehensive view of cattle management in the Iron Age and Roman period. The objectives will be achieved through the applied methodology, which consists of three lines. First, through Strontium isotope analysis, the local or non-local origin of cattle can be established. Second, biometrical analysis will be used to investigate developments in shape and size over time. And third, mortality profiles offer insight into how cattle were exploited. Two work packages correlate to the first two methods, while the third combines the results from the other work packages with mortality data to obtain a comprehensive view of cattle management. A fourth work package is concerned with dissemination of the results among an academic and non-academic audience, while the fifth covers training in statistics
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Resilient Oats: Improving Drought Stress Resistance in a Changing Climate'.

assistant: **Concept**

Providing food security in the face of climate change and increasingly frequent extreme heat and drought events is one of the greatest global challenges. Drought is the most influential environmental factor limiting crop yields for a growing world population and leading to significant economic losses. To safeguard agricultural production, it is crucial to develop high-yielding crops with improved water use efficiency. Oat (Avena sativa L.) is an emerging crop that offers significant benefits for human health and provides a nutrient-rich plant-based protein source with a low carbon footprint. However, oats are sensitive to drought and progress in breeding drought-resistant varieties, while urgently needed, is limited. The oat genome is characterised by its enormous size, high repeat content, and complex polyploid structure. Therefore, efforts to investigate complex agricultural traits such as drought stress resistance have long been hampered by the lack of genomics resources. Recently, a fully annotated reference genome sequence of Avena sativa became available, to which I contributed significantly, representing a fundamental breakthrough. RESIST will take on the challenging high-priority task of deciphering the molecular basis of drought stress resistance in oat, providing substantial solutions to secure yields of this emerging, healthy and versatile crop. To this end, RESIST will exploit innovations in plant genomics and in particular oat genetics, employ cutting-edge high-throughput phenotyping methods and establish gene editing protocols that provide an innovative basis for accelerated and targeted breeding of oats. RESIST provides the indispensable foundation for the development of better-performing oat varieties under drought conditions to secure oat yields as a su
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Healthcare by biosensor measurements and networking' (CARE-MAN), addressing dissemination and exploitation.

assistant: **Impact**

Diagnostics at hospitals is based either on large-scale automated equipment or ELISA techniques based on bioassays which are not suitable for bedside and emergency medicine. Therefore CARE-MAN will provide a validated, intelligent, next-generation diagnostic device and system based on biosensor technology with new, radically enhanced detection capabilities and integrated sample-handling to address the most common diagnostic problems in the EU like cardiovascular disease, coagulation disorders, chronic/acute inflammation, cancer, thyroid disorders. The integration of eHealth capabilities is achieved through networking functions and interfaces to current and future medical data systems. To follow the requirements of the variety of serious diseases, modules of sample preparation, fluidics, assay formats and optical and electrochemoluminescent transduction principles will be integrated in a new modular multi-analyte technological system in cooperation with diagnostic and IT companies. The system will reduce sample volumes and improve limit of detection, make the point-of-care diagnostics fast, easy to handle and cost-effective and will provide an anticipating diagnostic help by networking and information technology. Hospitals are involved in the validation process taking into account the differences in healthcare and provide input to improve the instrumentation. Working biosensing systems are modified to allow development of immunoassay strategies from the start and give chance to improve instrumental setups even in the first period. Later, system integration will not only set up a technological modular system for hospitals but also for family doctors and in future, for bedside home surveillance. The involvement of legislatory bodies and representatives of health insurances
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'MALDI-TOF mass spectrometry metabolite screening assays for drug discovery in human disease', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Discovery for drug targets is a key step within the process of drug development, and is the corner stone in the pharmaceutical industry. This is mostly achieved by high-throughput screening (HTS) approaches in which a large number of chemical substances are assayed for a specific effect or activity in diverse areas of biology. Mass spectrometry (MS) has become a widely adopted tool in this field as it offers the possibility to simultaneously track molecules in a label-free manner, provides excellent signal to noise, reproducibility, assay precision, and a significantly reduced reagent cost when compared to fluorescence-based assays. Matrix-assisted laser/desorption ionisation time of flight (MALDI-TOF) is the most validated surface ionisation method for HTS approaches, but reported applications of this technology have been limited to in vitro assays with simple readouts and to peptide/protein-centric activity assays. To date, comprehensive and unbiased metabolomics based HTS approaches for cellular assays with MALDI-TOF have not been explored. The objective of this fellowship is to set up a MALDI-TOF based cellular assay for HTS metabolomics drug discovery in order to identify a set of metabolites to screen which will enable us to unbiasly and comprehensibly measure, in a HT manner, how drugs affect different metabolic pathways while simultaneously mapping the metabolic profile of the cell. First, I will develop a robust protocol for the detection, identification, and quantification of ~50 small metabolites for cellular assays. Then, I will apply this protocol to track metabolites in a pulmonary fibrosis cellular model, as well as in fibrotic lung tissue sections using MS imaging. The goal is to compare a disease model with the control to see how drugs are affecting the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'KNOWLEDGE-BASED ENTREPRENEURSHIP: INNOVATION, NETWORKS ANS SYSTEMS'.

assistant: **Objectives**

KEINS purports to examine the relevance and features of knowledge-based entrepreneurship (KBE) in Europe. KEINS will look at three types of KBE: start-up entrepreneurship, corporate entrepreneurship and academic entrepreneurship. Entrepreneurs are seen as knowledge operators, dedicated to the integration of different knowledge assets and the creation of new ones. They may perform this function either by setting up new companies, or by activating social, financial, and expertise networks from within existing companies, universities or other organizations. KEINS will integrate different methodologies and approaches, ranging from appreciative and formal theorizing to case studies and quantitative empirical work. Special care will devoted to include different industries and countries, with an extensive coverage of Accession Countries. KEINS pursues five objectives: 1. to discuss and refine current concepts of KBE (How is KBE dealt with in the current literature on the firm, entry, national systems of innovation, and technology transfer? How can we improve upon them?) 2. to explore the relationship between KBE and innovation (How much does KBE contribute to innovation? Which technologies do owe their existence/development to corporate or academic initiatives, or to start-ups?) 3. to define the role of networks of alliances, information, finance and social ties (How much does KBE rely on the different kinds of networks? To what extent do those networks overlap?) 4. to assess KBE in different sectoral and national systems of innovation (for example: What are the main differences between Accession Countries and current EU members?) 5. to produce policy recommendations (Is KBE key for European growth and competitiveness? How can KBE be effectively promoted? What steps Accession
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Harnessing bacteria-driven interfacial dynamics for optimised soil drying' in the context of a Horizon Europe call.

assistant: **Objectives**

Bacteria abound in the soil, contributing to major global geocycles and plant growth. Bioaugmentation, the stimulation or tuning of this natural microbiome to optimize its function for human gain, has recently been used with success to manipulate biological interactions. However, we lack the understanding of the impact of bacteria on the physics of soil that would be necessary to direct bioaugmentation toward abiotic goals such as limiting water loss to drying – one fifth of all water deposited on land is rapidly lost back to the atmosphere by this process. Using novel experimental and theoretical approaches, BACTODRY will bring bioaugmentation for reduced drying toward feasibility by harnessing the control bacteria exert on macroscale drying via alteration of the physico-chemistry of the numerous microscopic air–water interfaces in a drying porous soil. We will develop microfluidic devices capturing features of air–water interfaces at the scale of one to a few pores while giving unprecedented access to bacterial and interfacial dynamics at the microscale (WP1–2), and use them to gain quantitative insight into the bio-physico-chemical couplings that set fluid flows and evaporative rate. How these microscale relations upscale will be tested in granular column experiments, shedding light on interface dynamics in complex 3D structures (WP3). We will then develop an in situ selective chip for isolating natural bacteria that impact drying (WP4). Building on the insights gained in WP1–4, we will demonstrate how soil can be bioaugmented with bacteria selected from the environment to achieve reduced evaporative drying in the field (WP5). BACTODRY’s novel methods and insights will have far-reaching impacts on our understanding of natural surface-active molecules, the study of mi