RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Responsible Research and Innovation in Business and Industry in the Domain of ICT for, Health, Demographic Change and Wellbeing' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The Responsible-Industry project will design an Exemplar Implementation Plan of RRI in Industry to demonstrate how industry can work productively together with societal actors and integrate principles and methodologies of Responsible Research and Innovation (RRI) into research and innovation processes. To achieve maximum impact where it is most needed, the implementation plan will focus on the grand challenge of health, demographic change and wellbeing. More specifically the project will focus on the role that research and innovation in ICT can play in addressing this challenge.Responsible-Industry will guide interactive discussions between leading industry partners, established RRI experts, policy advisors and civil society organisations to drive the research and innovation process with the principles of RRI in mind. In doing so, Responsible-Industry will achieve the following objectives:- Synthesis of current discourses on RRI in the industrial context, based on an extensive literature review, 30 in-depth interviews with industry thought leaders, 5 bottom-up case studies and 2 Horizon Scanning reports.- Investigation, through practical cases and in depth dialogue with stakeholders (industry, CSOs, policy makers and emerging global stakeholders), of processes, challenges and opportunities leading to responsible innovation along specific value chains of products and applications.- International Delphi Study of RRI in industry involving 130-150 stakeholders and an international Multi-Stakeholder workshop.- Development of a detailed implementation plan to be tested in at least 4 pilot projects.- Reflection on the viability of the implementation plan, supported by least 15 industry-driven focus groups.- Development of models of RRI in industry as a basis of specific recomm
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Machining of next generation packages and silicon wafers' (MAPAS), addressing dissemination and exploitation.

assistant: **Impact**

Within the era of mobile technologies and increasing intelligence of microelectronic devices, there is a heavy demand for higher integration of such components. Especially, the smart card, smart label, and smart fail industry requires for still thinner and smaller chips. However, there exists a strong and world-wide deficit in the back-end processes and machinery for thin silicon dice and wafer-level packages. The MAPAS project challenges this insufficiency by investigating and evaluating new processes like laser dicing. By using very short laser pulses and expanding the wavelength spectrum new phenomena can be exploited to machine silicon with the highest precision. Based on the achieved results a new machining system has to be developed, constructed, and realised. The end-users from the electronics industry will be able to use the machining results to derive optimised design rules for highly integrated packages.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Genome-wide screen for new centrosome position regulators' (CENTROLOC), addressing dissemination and exploitation.

assistant: **Impact**

Centrosomes are the main microtubule-organizing centers in animal cells and their structure and function are extremely well conserved across evolution. Centrosome localization is a dynamic, cell cycle, and cell type regulated process that plays many critical roles in a variety of cell functions and animal development. I have recently published, as part of my work in the lab of Pierre Gönczy, a siRNA genome wide screen that has successfully identified new regulators of centriole duplication. In this work we have used a HeLa cell line stably expressing the centriolar protein Centrin-1 tagged to GFP. We have developed an algorithm to automatically identify GFP positive foci and use it to measure among other features centriole number. Remarkably, there is information that was extracted from the collection of images that remain to be analyzed and that can reveal new features about centrosome biology. One exciting example is the analysis of centriole position within the cell. I aim to use the data to identify new candidates required for proper centrosome localization in a genome-wide scale. The more straightforward way to achieve this goal will be to identify those conditions where centrosome position is not in close proximity to the nucleus. As a proof of principle I have searched in our database for genes previously reported in literature to influence centrosome-nucleus connection. Preliminary visual inspection showed examples where the percentage of cells displaying an increased nucleus-centriole distance was significantly higher than in control conditions (i.e. BICD2, CENP-F, DCTN1, Nesprin-3 and SUN-1). This preliminary data encourage me to embark on a more systematic and quantitative search of candidates in a genome-wide scale. In order to perform this project I will re
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Understanding vaccination hesitancy and evaluating single dose and gender-neutral vaccination for improving uptake of HPV vaccines in West and East Africa.' (IMPROVE-HPV) targeting Horizon Europe.

assistant: **Abstract**

Cervical cancer, caused by human papillomavirus (HPV), is almost entirely preventable through prophylactic HPV vaccination. Many countries have yet to implement HPV vaccination programmes or are struggling to achieve high vaccine coverage. This presents a major challenge for meeting the World Health Organisation (WHO) cervical cancer elimination target, with 90% of 15 year-old girls being vaccinated against HPV by 2030. Originally licenced as multidose vaccines, WHO has recently recommended that countries can offer a single HPV vaccine dose to 9-20 year olds. The IMPROVE-HPV consortium, a partnership of research institutions in Tanzania, Nigeria, UK and Spain, will investigate barriers to HPV vaccine uptake and the impact and acceptability of new HPV vaccine delivery strategies to improve vaccine coverage and effectiveness and reduce hesitancy. The consortium builds on previous successful collaborations in HPV epidemiology and vaccine research and qualitative research on barriers and facilitators to vaccine uptake. Tanzania has a multidose HPV vaccination programme in girls but will change to a single dose regimen in 2024. A gender-neutral HPV vaccination strategy is currently being implemented in Tanzania as part of a large cluster-randomised trial. Nigeria is one of the first countries to introduce national HPV vaccination with a single dose. Using these opportunities, IMPROVE-HPV will evaluate vaccine effectiveness, uptake and the factors affecting acceptability of (1) HPV two-dose vaccination delivery in females, (2) introducing or changing to a single dose vaccine regimen (3) gender-neutral HPV vaccination, and will also (4) investigate factors influencing vaccine hesitancy, community engagement and perceptions of HPV vaccines. The workplan directly addresses effec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Incorporating flexibility into protein-ligand docking' (IFLPD).

assistant: **Innovation**

One of the major goals of current drug discovery methods is the correct treatment of the flexibility of the receptor (i.e., protein) in small ligand docking. Computer-aided drug discovery through ligand docking-based virtual screening is already a key component in the lengthy and costly process of developing new drugs not only for academy but also for the pharmaceutical industries. In this proposal, we want to incorporate flexibility considerations into structure based drug discovery by using theoretical methods such as Molecular Dynamics and Normal Mode Analysis. The approach will be a step toward the integration of dynamics in structure-based of drug discovery.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Mapping dEndritic inforMation prOcessing in behaving mice using simultaneous spatio-tempoRal voltage and calcium Imaging and wholE-cell electrophySiology' (MEMORIES).

assistant: **Concept**

Dendritic information processing is fundamental to how we perceive and interact with the world around us. Spatio-temporal maps of dendritic voltage reveal how information is processed in the brain, but remain unexplored in awake animals, since no recording technique was previously available to study them.I recently developed a novel technique for spatio-temporal mapping of dendritic processing in unparalleled detail (Roome and Kuhn, 2018). My pioneering experiments provided the first observation of spatio-temporal dendritic voltage signalling in vivo. For the first time, I combined simultaneous dendritic voltage and calcium imaging with somatic recording in cerebellar Purkinje neurons of awake mice to reveal complex dendritic processes, including discrete dendritic spikelets, back-propagating action potentials and localized subthreshold signalling. Using my novel technique to record from neocortical Pyramidal neurons, I will now investigate dendritic processing in behaving mice, to explore how memories are formed during learning. I will focus on how back-propagating action potentials contribute to dendritic processing, through modulation of synaptic plasticity. The Laboratory of Sensory Processing (Prof. Carl Petersen) at EPFL, Switzerland, is specialized for investigating synaptic mechanisms of sensory processing and highly experienced in whole-cell recording and optical imaging during animal behaviour and training; all of which are critical for the success of this project. This fellowship will be instrumental in propelling a technique, that I have been committed to developing, towards state-of-the-art research in neuroscience. It will provide an ideal avenue for introducing a new technique to Europe, through a world leading laboratory, and prove invaluable for sharing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Biological Impact of Oil Pollution in Arctic and Deep-sea Environment' in the context of a Horizon 2020 call.

assistant: **Objectives**

The increase demand of oil, associated with the depletion of easily exploitable oil deposits is leading the oil industry to intensify the search for new oil areas and exploit deposits previously considered as economically unprofitable. These new oil research areas are mostly located in Arctic waters and in the ""offshore"" areas in deep waters. However, very few studies have investigated the biological impacts of oil contamination in these very specific areas. Practically, the research actions will estimate the potential synergistic effect of oil, warming and hypoxia on a key Arctic species, polar cod Boreogadus saida (Work package 1, WP1).The project will then will focus on the impacts of the soluble fraction of oil on the metabolism of deep benthic species, in particular Lophelia pertusa and Eurythenes gryllus (WP 2). WP3 will consist of an applied study in order to validate two experimental set-ups which could make possible the assessment of the impact of oil in deep-sea environments. Finally, WP4 will be devoted to provide recommendations to perform a relevant NEBA in Arctic and deep-sea areas. The complementarities between the applicant and the supervisors profiles, associated with partner organizations skills ensure the realization of this innovative project and the dissemination and exploitation of the different results.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Enhancement of the Material Point Method for fluid-structure interaction and erosion' under Seventh Framework.

assistant: **Concept**

In the framework of the proposed cooperation between Deltares and Technical University of Lodz, the material point method will be enhanced to allow for the simulation of fluid-structure interaction and erosion. The dumping of a geocontainer into flowing water and its impact on the seafloor will be investigated with this generalised MPM. Furthermore, simple problems of erosion will be studied with the developed method.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Genetic analysis and engineering of aluminium tolerance in maize and in model plants', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The main objectives are as follows:* The mapping of genes responsible for aluminium tolerance in maize by using genetic and molecular methods.* The identification of genes associated with aluminium tolerance in maize and analysis of their expression.* The identification of Arabidopsis ecotypes tolerant and sensitive to aluminium and analysis of the modification of the rhizosphere.* Production of transgenic plants altered in the expression of genes involved in the biosynthesis of organic acids.* Analysis of specific root epidermis promoters in transgenic tobacco and maize plants.Expected OutcomeThe project intends to provide tools for the analysis of aluminium tolerance in maize such as molecular markers and cDNA clones corresponding to genes induced or repressed in different aluminium conditions. A screening in a model plant, Arabidopsis thaliana, will be carried out in order to obtain tolerant and sensitive ecotypes. Transgenic tobacco and maize plants with altered organic acid biosynthesis will be obtained and they will be analyzed for aluminium tolerance. Transgenic plants will also be used to analyze promoters specific for root epidermis.The key activities envisaged are:* Mapping of maize genes involved in aluminium tolerance using available segregant populations and molecular marker methodology.* Identification of genes involved in aluminium tolerance by differential display and differential screening between tolerant and sensitive maize lines in the presence or absence of aluminium. Analysis of the structure and expression of selected clones.* Production of transgenic and tobacco plants overexpressing bacterial citrate synthase and overexpression of PEPC and MDH. Analysis of variations in organic acid production and secretion in root exudates. Study of the toleran
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Transformative Digital Air Vehicle with IoT Sensors for Safer Urban Skies' (AVATAR), addressing dissemination and exploitation.

assistant: **Impact**

AVATAR is dedicated to developing a digital twin platform to enable continuous monitoring of the vehicle during its service life for the purpose predictive maintenance. AVATARs digital twin model acts in parallel to the real structure and provides, where necessary, an early warning of operational behaviour that deviates from expected (simulated). Additionally, by recording the actual load spectrum that each air vehicle experiences during every flight, it will optimize the individual service life, which contributes towards a sustainable air mobility. AVATARs will contribute to an increase safety of urban skies and has the potential to optimise the design and performance of air vehicles by providing real load data for each vehicle. The IoT sensing skin proposed by AVATAR is a key enabler for real-time critical operational information acquisition and connectivity between the physical aircraft and the digital counterpart through wireless communication. AVATAR DT platform will provide a seamless integration of  IoT, big data and machine learning to collect, compute and predict. AVATAR will conform to the modern approach towards developing a digital twin based on different types of data and advanced analytical methods which eliminates the need for the real air vehicle and the virtual models to be directly connected and builds this connection through ML and AI. AVATAR contributes to the acceleration of digital transformation of air mobility, particularly in urban setting.


**Keywords:** Digital Twin, IoT, Sensing skin, Structural Health Monitoring, Predictive maintenance, Advance Analytics, Cloud base solutions, Big Data, Diagnosis and Prognosis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Perceptual Realities: Optimizing XR through Perceptually-Informed Experiences' under Horizon Europe.

assistant: **Concept**

Extended Reality (XR) technologies—including Virtual Reality (VR), Mixed Reality (MR), and Augmented Reality (AR)—are rapidly evolving, offering immersive experiences that blend the physical and virtual worlds. While progress has been made in understanding basic perceptual and behavioral processes to create high-quality, engaging content, current perceptual models often oversimplify how users experience these environments. To create truly immersive and effective XR experiences, we need a deeper understanding of how users perceive complex, highly realistic immersive scenarios. Whether to optimize visual fidelity, manage attention, or improve system performance, human perception plays a central role in the XR experience.PROXIE aims to address this by studying perception in XR environments that mirror the complexity of real-world XR applications, pursuing ecological validity. Rather than focusing on simplified, constrained scenarios as in existing research, we will explore how perception is shaped by both the environment and the tasks users perform. By understanding how users process multisensory inputs while actively engaging in realistic, interactive tasks such as search or free exploration, we can inform content generation, visualization algorithms, and even hardware design to improve XR experiences.Our goal is to develop computational models of perception that predict how users perceive and respond to immersive environments—whether fully virtual or augmented—based on sensory inputs and tasks. These models will anticipate how users process their surroundings, allowing XR systems to adapt in real time. For example, the models may help optimize visual rendering, sensory feedback, and the overall user experience to match user needs. This will enhance applications such as t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Human-centric Digital Twin Approaches to Trustworthy AI and Robotics for Improved Working Conditions' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

AI4Work will investigate practical methods and tools for optimal sharing of work between humans and AI/robots. AI and robotics are likely to be most powerful means for radical improvement of working conditions in diverse domains, as they can support human operators in diverse tasks starting from difficult and tedious manual labor tasks up to complex decision-making tasks. The vision of the AI4Work project is to improve communication and collaboration between humans, AI and robots, allowing for an improvement of the working conditions within different processes in organisations in several domains in terms of increased efficiency of work, reduction in stress upon employees, increased confidence in decision-making process etc.  Due to the high level of uncertainty in modern organisations an appropriate balance between human and machine activities must be found. The key assumption is that to cope with the required flexibility and dynamics, Sliding Work Sharing (SWS), where this balance varies during the operation depending on the situational context, machine-based confidence levels and human interactions, is likely to be the most appropriate for modern organisations. The key challenge of the project is to develop a set of common methods and tools (methodology framework, digital twin service platform, SW building blocks for SWS) that can be applied in diverse sectors and with different AI/robotics services, allowing for an effective experience exchange. The project will make use of living digital twins of working systems as a mean to increase efficiency and trustworthiness of AI/robotics solutions. By this, the project, aiming at improved quality of jobs and creating more decent work for human operators, will contribute to the acceptance of the AI/robots support of work in d