RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Providing dependable and adaptive service technology for pervasive information and communication'.

assistant: **Concept**

Ubiquitous networking provides mobile users with unique features for seamlessly accessing networked services. However, service provisioning for B3G distributed computing platforms faces numerous challenges, among which are: developing services that can be easily deployed on a wide range of evolving infrastructures, from networks of devices to standalone wireless resource-constrained handheld devices; making services resource-aware so that they can benefit from networked resources and related services; and ensuring that users always experience the best Quality of Service (QoS) possible according to their specific situation. In addition, services must be provisioned in a way that guarantees their dependability.The PLASTIC project will develop a comprehensive provisioning platform for software services deployed over B3G networks. The project will build upon both Web services and more standard component-based technologies. The PLASTIC platform will specifically integrate innovative methods and tools for service development, from design to validation, and a supporting middleware for service provisioning in B3G networks. The platform will enable dynamic adaptation of services to the environment with respect to resource availability and delivered QoS, via a development paradigm based on Service Level Agreements and resource-aware programming. The middleware will be service oriented, to enable integration and composition of heterogeneous software services from both infrastructure-based and ad hoc networks.The middleware will integrate key functions for supporting the management of adaptive services in the open wireless environment, dealing with resource awareness and dependability. The project will assess the PLASTIC platform through representative and challenging mobile e-serv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Targeting the metabolism-immune system connections in Cancer'.

assistant: **Innovation**

Cancer cells show common features of profound metabolic changes and escape from the immune system, independently of their tissue of origin. These metabolic adaptations are not limited to glucose metabolism (the ""Warburg effect"") but are more general and affect several metabolic pathways in cancer cells as well as in the stroma, including immune cells. This network will explore how nutrients and hypoxia regulate the tumor-immune system interplay, and how this communication is controlled by oncogenes, metabolic regulators and current or potential drugs targeting metabolism. Understanding how metabolism can affect tumor cells and the anti-cancer immune response represents a potential therapeutic intervention point that can be exploited to develop novel therapies and new diagnostic and prognostic markers. The development of therapies targeting cancer metabolism is hampered by: 1) the complexity of the regulation that metabolism exerts on many different tumor layers, which requires multidisciplinary collaborations, and 2) the shortage of scientists that can navigate with ease between academic, industrial and clinical sectors and have the scientific and complementary skills to convert research findings into commercial and clinical applications. This network provides a pan-European interdisciplinary and intersectoral training program of excellence bringing young researchers together with World leading academics, clinicians, pharma industry members, corporate research and dissemination and outreach specialists. As part of the research training, the consortium will conduct a coherent and integrated set of hypothesis-driven research projects that are aimed at discovering, describing and exploiting how metabolism at the cell and the whole body levels is integrated with modulatio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Vicariance and speciation - a molecular phylogenetic test using ithomiine butterflies'.

assistant: **Concept**

The forest nymphalid butterfly subfamily Ithomiinae has been and still is instrumental to understand mimicry development, one of the best examples of natural selection driving colour patterns. Their differentiation across the Amazonian lowlands has been used to support allopatric speciation theory by fragmentation of rain forest during the glacial period. To test whether the extant patterns of two ithomiine genera (Hypothyris and Melinaea) reflect historical or ecological origins, we plan to collect population samples of the main species included in the two genera and examine the phylogenetic hypothesis of unrelated, co-mimetic groups. Because of the similarity due to mimicry between species, we will use a molecular approach to shed light on alpha-taxonomy as well as species relationships, leading to a better understanding of the evolution of mimicry in both these genera. The choice of nuclear and mitochondrial genes would improve the phylogenetic resolution at both intra- and inter-specific levels, between as many species and taxonomically distinctive populations as possible. If cladograms of unrelated groups of sympatric species are concordant, we will confirm the refugial hypothesis (speciation by isolation between forest fragmented regions) and, using a molecular clock, we will test of vicariant origins through analysis of divergence times for concordant clades.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The evolutionary significance of synonymous variations: Can codon usage preferences drive the propagation of antibiotic resistance?' (HGTCODONUSE), addressing dissemination and exploitation.

assistant: **Impact**

The intensive use of antibiotics provided an unprecedented improvement in infectious disease treatments but at the expense of creating ideal conditions for the selection of widespread resistance. Propagation of antibiotic resistances is favoured by horizontal gene transfer and by bacterial life in multispecies community. However, compositions of resistome and bacterial communities are often correlated, suggesting that propagation of resistances does not occur at random. This project will test the hypothesis that mismatch in codon preferences between the transferred genes and the receiving genome is a fundamental factor shaping resistome structure and evolution. Such central role of codon preferences may have been hitherto overlooked. The project combines mutant collection characterization, experimental evolution approaches –one in a multispecies context and one in a variable environment context-, full genome sequencing of evolved populations, phylogenomics and mathematical modelling integrating the experimental results of the other approaches, and generating a predictive tool about the evolutionary outcome of various real-life situations.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Electrospray-Mediated Delivery of Biological Molecules into Mammalian Cells' in the context of a Seventh Framework call.

assistant: **Objectives**

This partnership has been created to address the critically poor efficacy of existing treatment strategies to treat lung disease, a major health problem in the EU. The project will research and develop a novel process involving electrospray to deliver biomolecule-based drugs into cells. The action requires intersectorial collaboration between partners with complementary expertise in biological drug delivery, mechanical and manufacturing engineering and microfluidics technologies. The problem will be tackled by researching the parameters that influence electrospray generation and its ability to successfully deliver active biomolecules into cells. The term ‘electrospray’ refers to the process where electrical charges are provided to a fluid in order to generate a very fine spray of the fluid. Applications of electrospray technology include mass spectrometry, chemical deposition and colloid thrusters. Recently, the process has been applied to areas of biology such as protein mass spectrometry, depositing biological material during tissue engineering and the production of protein microarrays. However, the fundamental parameters underlying electrospray formation are poorly understood, limiting full exploitation of the potential of this phenomenon. We have developed a novel electrospray system which we have successfully used to demonstrate a novel application of delivering biological molecules into cells such that they remain functional within the cell. This technology holds substantial potential as a novel drug delivery method. In this interdisciplinary action, we aim to increase understanding of the physical processes involved in electrospray generation, to develop the technology and to determine its potential to deliver of a wide range of biological molecules into cells. T
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Aviation Noise Impact Management through Novel Approaches' (ANIMA), addressing dissemination and exploitation.

assistant: **Impact**

Aircraft noise continues to cause adverse effects on quality of life and public health in airports’ neighbourhood. To address this challenge and ensure airports will have the capability to respond to the growing traffic demand, ANIMA aims to develop new methodologies and tools to manage and mitigate the impact of aviation noise, improving the quality of life near airports while facilitating airports growth and competitiveness of the EU aviation sector within the environmental limits, also considering 24/7 operations. Hence, ANIMA carries out critical review and assessment of noise impacts and existing management practices to establish best practices’ guidelines for an effective management of annoyance beyond ICAO Balanced Approach (WP2); develops a better understanding to address community annoyance, sleep disturbance and improve quality of life through pilot studies and surveys, assessing new methodologies reducing annoyance, testing novel and cost-effective solutions for land-use planning, using also mobile applications, the whole to derive new indicators (WP3); develops a 24/7 Noise Management Toolset to empower non-specialists with decision support capability and a 24/7 Design Toolset for researchers (WP4); tests and validates with end-users (airports and community) an “Aviation noise community platform”, gathering tools and best practices, facilitating consensus building and engaging communities in the mitigation process, ensuring exploitation of the results (WP5); supports the coordination of national and EU research activities, establishing a common strategic research roadmap for aviation noise reduction through the involvement of a pan-European network of experts and project leaders, also addressing international collaboration opportunities (WP6). ANIMA, a 4-yea
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Studying very high redshift Galaxies through Gravitational Telescopes' (HIGHZLENS).

assistant: **Innovation**

This program aims to study the formation and evolution of high redshift galaxies strongly lensed by a  massive cluster acting as a gravitational lens.   I plan to study the assembly history of galaxies at 2 < z < 5 through very detailed analysis of highly magnified arcs with Integral Field Spectroscopy, in order to compare the local star formation rate and spectrophotometric properties at a spatial resolution of 0.1-0.2 kpc, allowed by the gravitational lensing effect which stretches the observed physical scales. I will use the new PanSTARRS survey to look for more examples of highly magnified arcs in galaxy-galaxy events.   I will perform a large survey for very high redshift lensed galaxies (6<z<12) identified as near-infrared dropouts and undertake the spectroscopic follow-up using the forthcoming multi-object spectrographs at high resolution. By comparing the number counts, luminosity functions and spectroscopic results with theoretical expectations from semi-analytical models, I will build a complete picture of the star formation history in the early Universe, well ahead of the commissioning of the next generation of large-diameter (30m) telescopes such as the ELTs, or the JWST.  All this research will be performed using the latest instruments on large-diameter telescopes accessible to the Durham group (Gemini, ESO observatories, Magellan), including the available Integral Field Units, and the space telescope. The programme includes technical training on reduction and analysis of 3D datasets, project management, collaboration with different groups and presentation/publication of scientific results.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Aerodynamic Design Optimisation of a Helicopter Fuselage including a Rotating Rotor Head' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The project is aimed on reducing the aerodynamic drag of light weight class helicopters by shape optimization of components which typically produce a large amount of aerodynamic drag. Both experimental and numerical simulations are conducted on a helicopter fuselage configuration with rotating rotor head. The main effort is on three wind tunnel campaigns analyzing the aerodynamic characteristics of the baseline configuration and of three modified configurations. The design modifications concentrate on the landing skids and on the rotor head to reduce the aerodynamic drag associated with these components. Effects of spoilers, strakes and vortex generators are addressed as well to influence the fuselage wake for further drag reduction. In order to create a detailed data base, the wind tunnel experiments include force measurements to obtain aerodynamic forces and moments, pressure measurements to capture steady and unsteady surface pressure distributions and field measurements of mean and fluctuating velocity components for wake analysis. A new wind tunnel model consisting of fuselage, tailboom segment and rotating rotor head will be designed, manufactured and instrumented to conduct the wind tunnel tests. The model will provide high modularity of its components to exchange them easily for shape modification with respect to drag reduction. The experimental tasks are supplemented by computational fluid dynamics work to numerically cross-check the wind tunnel data for selected cases.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Virginia Woolf and Italian Readers' in the context of a Horizon 2020 call.

assistant: **Objectives**

This project examines the reception of Virginia Woolf in Italy and it will lead to the first multi-media comprehensive study of her reception in Italian culture. Employing an archive-based interdisciplinary approach drawing on reception studies, periodical studies, publishing history, the project will trace the waves of her reception, from Fascism to the present. To do so, it will examine the key stages of Woolf’s reception in relation to the political, cultural and institutional factors that influenced publishers and translators over the years and it will map out the publishers, translators, and cultural gate-keepers that patronised Woolf’s works in the Italian context. The project will focus on the censorship mechanisms put in place by Fascism and how Woolf translators challenged them; the circulation of Woolf works in the post-war Neorealist phase; the role her work played in the rise of the Italian feminist movements in the 1970s; and finally how, since the late 1990s, the reception of the transmedial adaptations of her work consolidated Woolf as a cultural icon in Italy. In addition to traditional scholarly outputs, this project will create a digital open-access database which will serve as a research tool for scholars, students and the lay public. Woolf’s work will be considered a litmus test for key moments of change in the Italian cultural industry. The study of Woolf’s Italian reception will, in turn, contribute to the growing scholarly interest in the reception of Anglophone Modernist writers in European literary marketplaces by embracing the recent calls to globalise the reach of Anglophone modernism and by affirming how peripheral and context-specific concerns help to reconsider the adaptability of modernist innovations and to question the idea that transfer
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The power of grape extracts: antimicrobial and antioxidant properties to prevent the use of antibiotics in farmed animals' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

NeoGiANT  is an innovative action coordinated by the University of Santiago de Compostela (Spain). NeoGiANT aims at developing a new set of products (animal feed, treatment products, sperm extenders) able to decrease the use of antibiotics on farmed animals and substitute synthetic preservatives. These new products, based on natural extracts, using an advanced isolation technique, will not only avoid the growth of microorganisms but also improve the health and welfare of the animals increasing profitability.The proposal is based on the use of biomass sources that can provide cost-effective, efficient and green solutions to obtain functional ingredients in sustainable circular economy production systems. The new products  developed will be based on one extract of natural origin called e-Vitis (obtained from Vitis vinifera). e-Vitis is isolated using as raw material grape marc from the production of high quality white wines, that preserves, after the winemaking process, a significant load of bioactive compounds originally present in the grape. In order to obtain a multicomponent ready-to-use extract using green solvent extraction approaches NeoGiANT is going to apply an alternative methodology to conventional extraction, to disrupt the grape marc and extract the bioactive compounds. This innovative green technology is simple, the conditions required are mild (energy savings), and can be easily scaled-up.The advanced properties of the natural extract will provide antimicrobial and antioxidant protection to the animals improving their performance and serving as a prophylactic treatment. The target products to be developed will be designed to control a large number of infectious diseases of paramount importance in animal production, both in livestock and aquaculture.Moreover
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Development of flywheel motor generator unit for peak power application in electrically propelled vehicles'.

assistant: **Concept**

Objectives The objective of the research is to design, manufacture, test on bench and on vehicle a flywheel motor/generator unit. This will demonstrate the technical feasibility, test the operational features, evaluate the advantages in terms of energy saving for electric vehicles, and enable the assessment of the economical benefits as well as the impact in terms of global energy conservation. The solution will be developed according to the specifications that will be defined in the first part of the research. In principle these are expected to be:  rotational speed = 50.000 to 60.000 rpm  total weight of the unit = 35 kg Technical Approach The objectives will be addressed (according to the work plan outlined in the following section) following a systems engineering approach based on the integration of available technological means, supported by appropriate simulations in the design phases and complemented by extensive testing on separate components and on complete flywheel units on the bench and on a vehicle. Special care and priority will be given to the following aspects: Safety:  this aspect will be considered throughout the development process, from the calculation of rim, dimensions, containment ring with impact analysis, to dynamic analysis and bench tests, up to burst test; fatigue behaviour of components will also be taken into account.  Energy efficiency:  this issue will be tackled mainly by a new design for a low loss electrical machine and power electronics, as well as with appropriate definition of magnetic bearings system. Expected Achievements and Exploitation The key achievements of the envisaged solution will be:  high input/output energy efficiency over the range of the flywheel operating conditions  high specific power (over 1 kW/kg referred to the