RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Transferring Activomics into the Clinical Setting' (TACTICS).

assistant: **Concept**

Transferring Activomics into the Clinical Setting (TACTICS). Advancing our proprietary biomarker discovery tool, Activomics, into the clinical laboratory represents an exciting milestone in the introduction of this disruptive technology to the global diagnostics market. Unlike current protein-concentration focussed diagnostics, such as ELISA and MS proteomics, our approach switches the emphasis towards the enzymatic activities of a subset of these proteins, vital cell-signalling enzymes inextricably linked to disease and its progression. We have developed highly sensitive methods to detect Activomic biomarkers in blood. Screening of sera obtained from large patient cohorts led us to identify a novel Activomic biomarker that can differentiate IBD (Inflammatory Bowel Disease) patients from healthy and unhealthy controls with high accuracy (86%) and sensitivity (86%). This first effective serological marker for IBD promises to be a major breakthrough in the diagnostics and/or prognostics of this debilitating disease that counts millions of sufferers worldwide. In Europe alone, over 1 million people currently have the disease, bringing with it a major toll on public health and a concomitant heavy economic burden for the healthcare system and taxpayer. Better diagnosis and targeted therapy of IBD would reduce suffering and costs alike. We participate in this call in order to achieve this goal, allowing us to devise a comprehensive business plan that will act as a roadmap to bring our biomarker into clinical diagnostic laboratories. SME-phase 2 funding and/or further private investment will be sought using the detailed business plan in order to fully validate clinical utility.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Vulnerable consumer empowerment in a smart meter world' (SMART-UP), addressing dissemination and exploitation.

assistant: **Impact**

The overarching aim of SMART-UP is to encourage the active use of Smart Meters and In-House Displays by vulnerable customers, in those Member States where the roll-out of Smart Meters has been embarked upon. Indeed, previous studies have shown that Smart Meters do not lead to energy savings in the residential sector unless households actively use them and are encouraged to modify their everyday practices. Our project intends to fill in this gap, while also raising awareness on demand response services. The way we intend to do so is by developing a training program for installers, social workers and other frontline staff in contact with vulnerable people, so that they can inform vulnerable consumers about the benefits brought about by smart metering and advise them on how to use their Smart Meter and In Home Display (IHD) units (where fitted) to best effect, each time they are in contact with them. Indeed, most vulnerable and low-income householders require a one-to-one and on-going support. The training packages will be tested and improved before getting disseminated towards the major actors involved in smart meters deployment (DSOs, energy utilities, installers…). From 50 to 100 installers or other frontline staff will be trained in each project partner’s country. Each of them will deliver face-to-face advise to 10 to 20 households, so as to reach 1,000 households in each country. DSO and energy utilities (depending on the national context) will be involved to provide the necessary support for this experiment and to ensure further dissemination of the training packages.Besides empowering vulnerable consumers, the project will serve to get some feedback on their specific needs and on the ways to appropriately communicate with them and help them take profit of smart mete
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Contrasting Neanderthal and modern human subsistence practices across Europe 50,000-40,000 years ago: an interdisciplinary approach to micro-scale taphonomy and BACterial bioerosion on BONE.'.

assistant: **Objectives**

The role of behavioural differences in the replacement of Neanderthals by modern humans remains a fundamental issue in human evolution. While recent archaeological and genetic studies have challenged ideas of Neanderthal behavioural inferiority, up-to-date assessments of differences in subsistence behaviour are still sparse. BACBONE fills this gap with a unique, interdisciplinary approach to bone taphonomy and subsistence practices 50,000-40,000 years ago, a time when both Neanderthals and modern humans were present in Europe.Subsistence reconstructions typically focus on larger, identifiable animal bone fragments and visible surface modifications. BACBONE combines, for the first time, a focus on the small bone fraction, now identifiable through Zooarchaeology by Mass Spectrometry (ZooMS), with the microscopic study of alterations to bone inner structures (histotaphonomy). This approach provides unique insights into patterns of carcass deposition and processing and has three objectives. First, forensic experiments and a reference database will provide essential background on micro-scale taphonomy. Second, histotaphonomic alterations will be mapped across key Neanderthal and early modern human assemblages from France and Bulgaria, combining the high through-put capacity of microtomography (micro-CT, virtual histology) with hard tissue histology. Third, interdisciplinary dataset integration will test for differences in Neanderthal and modern human subsistence practices at an assemblage and broader European scale. BACBONE will significantly advance methods in Palaeolithic archaeology and form the core of a new research programme at the interface between archaeology, biological anthropology and forensic science. Necessary training and expertise are exclusively available at
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Realigning British Romanticism: White Settler and Indigenous Writing in the British-Controlled Southern Hemisphere, 1783-1870'.

assistant: **Innovation**

SouthHem is a five-year research project designed to rethink and realign the nature and scope of British Romanticism by giving settler and indigenous literatures produced in the British-controlled Southern Hemisphere a more central role in defining the literary culture of the period 1783-1870. The project will carry out, for the first time, a detailed comparative analysis of these literatures and their interactions with British Romantic writing by focusing on case studies of encounter and transculturation in three transnational zones: “Zone 1” (Oceania): Australia and New Zealand; “Zone 2” (Southern Africa): the Cape Colony and Natal; and “Zone 3” (South-East Asia): Singapore, Java, and Malacca. The project has three inter-related aims: first, to consider the reciprocal transformations of literary themes, genres, standards, and forms in the British-controlled Southern Hemisphere and Britain; second, to rethink the ways in which nationhood, nationalism, and, in particular, national literature emerged in Britain and elsewhere by considering the global origins of nationalism; and third to problematise traditional periodisations of British Romanticism as beginning in the 1790s and ending in the 1830s. By radically expanding the type, provenance, and sample size of texts typically considered in studies of British Romanticism, this project will not only result in an important geographic, temporal, and conceptual rethinking of the field, but it will also provide a better understanding of how literary modernity emerged and developed outside of Europe and the Northern Hemisphere. As such, the project will facilitate larger cross-imperial and synthetic studies of the indigenous and settler literatures of the period.


**Keywords:** British Romanticism, Southern Hemisphere, transn
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Chemical biology of sphingolipids: fundamental studies and clinical applications' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Sphingolipids are major components of the human cell and are involved in human pathologies ranging from lysosomal storage disorders to type 2 diabetes. Here, we propose to establish an integrated research program for the study of sphingolipid metabolism, in health and disease. We will combine state-of-the-art synthetic organic chemistry, bioorganic chemistry, analytical chemistry, molecular biology and biochemistry techniques and concepts and apply these in an integrated chemical biology approach to study and manipulate sphingolipid metabolism in vivo and in vitro, using human cells and animal models. The program is subdivided in three individual research lines that are interconnected both in terms of technology development and in their biological context. 1) We will develop modified sphinganine derivatives and apply these to study sphingolipid homeostasis in cells derived from healthy and diseased (Gaucher, Fabry, Niemann-Pick A/B disease) individuals/animal models. This question will be addressed in a chemical metabolomics/lipidomics approach. 2) We will develop activity-based probes aimed at monitoring enzyme activity levels of glycosidases involved in (glyco)sphingolipid metabolism, in particular the enzymes that - when mutated and thereby reduced in activity- are responsible for the lysosomal storage disorders Gaucher disease and Fabry disease. 3) We will develop well-defined enzymes and chaperone proteins for directed correction of sphingolipid homeostasis in Gaucher, Fabry and Niemann-Pick A/B patients, via a newly designed semi-synthetic approach that combines sortase-mediated ligation with synthetic chemistry. Deliverables are a better understanding of the composition of the sphingolipid pool that are at the basis of lysosomal storage disorders, effective ways
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'POWERING THE WIRELESS REVOLUTION' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Wireless power transmission is slowly gaining popularity owing to Qi-based solutions embedded in our smartphones. However, this technology is far from having its momentum – users still complain about longer charging time compared to traditional chargers, heat being generated by devices, and the need for precise alignment. The limited efficiency of power transmission reaching app. 65%, and constrained power output (10W) highly reduces the scope of potential applications. What if we could increase the efficiency above 95% and raise transmitted power bar beyond 10 000 W? We could then easily address various application in multiple sectors such as consumer electronics, smart homes, automotive and even industrial domain. Such solution could become a leader at the wireless power transmission market expected to be worth USD 11.27 billion by 2020 and  growing at average CAGR of 23%. All this is possible with the breaking MePower solution from Meredot which already raised interest from global players. We developed a method for improving performance of magnetic resonant coupling which can be used to wirelessly supply power to any electric device with minimum power loss. By improving user experience and saving energy lost today by imperfect wireless charging solutions we aim to make life without cables truly possible. We have already demonstrated this with our IPR protected prototype charger capable of supplying power to consumer electronics surpassing all known standard based and proprietary solutions. Within the Phase 1 project we aim to evaluate technical and economic feasibility of matching our solution to the needs of mobile device end users, provide automotive sector with wireless EV charging, as well as industrial markets e.g. with ability to charge autonomous robots and dr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Process improvement object oriented software and reusable components'.

assistant: **Objectives**

Demand of reasonably prised high quality software sets rising demands for the productivity and quality assurance of the software production. Software projects tend to produce over and over again closely related individual software components. Software production by connecting components from multiple software houses tend to require excessive adjustment effort and produce heterogeneous software products.The objective is to improve the productivity and quality by using object oriented technology and thoroughly tested reusable components as well as introducing processes to support this in multivendor environment.THE EXPERIMENTTo achieve the objectives a reuse library and processes to produce, store and deliver reusable components are established. This is done in a two company environment to develop the capability for multi vendor software projects.The project will define the structure of the reuse library, standards for the components and practices for the production and exploitation of the components. The tools to be used are Select OMT case-tool, PVCS configuration management and Lotus Notes.The baseline application is a comprehensive building maintenance software product with a graphical features (drawings, GIS).KT-Datacenter employs 800 people, 100 of which work in the software development department. Opti Inter-Consult employs 25 people. Building maintenance project team is 16 people.EXPECTED IMPACT AND EXPERIENCEKT-Datacenter and Opti Inter-Consult expect to get better productivity and more effective procedures for joint ventures.KT-Datacenter and Opti Inter-Consult expect to get know-how on the factors that affect the productivity and preconditions of successful multivendor software production.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Photochemistry and radiation chemistry of environmentally and biologically relevant nitrogenated compounds - n-c1-amino acids'.

assistant: **Objectives**

Research objectives and content The main objectives of the project will be: i) Identification of the intermediates photochemically and radiation chemical generated from appropriate amino acids or from their N-derivatives (N-halo, N-nitroso etc.) ii) Study of the rectivity of the different intermediates generated under diffe- rent physicochemical conditions. iii) Identification of the reaction products for both the photochemical and radiation chemical processes. The accomplishment of these objectives will allow us to draw a detailed picture of reactivity of amino acids and their N-derivatives under UV irradiation or under the effect of ionizing radiation. Emphasis will be placed on the studies in aqueous solution, due to the importance c this medium both from the biochemical and from the environmental point of view. Experiments in media other than water are also planned if necessary to explain the observed reactivity. Training content (objective, benefit and expected impact) The main training objective is to acquire experience in the fields of flash photolysis and radiation chemistry. Provided the excellence of the host institution, this is expected to be a complete success. A second, very important, objective is to get enough experience in this kind of studies as to be able to continue with them in the future in the place of origin of the applicant (Galicia, Spain), which, as a less developed European region would benefit a lot from a new high-quality scientific team. Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Near Memory Computing'.

assistant: **Concept**

Near Memory Computing: Major bottlenecks for future computation is the slow communication over slow interconnects between big data memories and big data processing and also the slow overhead of data memory accesses. The NeMeCo EID network aims at solving this problem by proposing fundamentally different architectures, integrating computation and memory, and using reconfigurable accelerators. Research topics of this project are: new, non-Von-Neumann architectures,  automated design of reconfigurable accelerators, advanced memory hierarchy based on both volatile and non-volatile memory components, and corresponding compiler, algorithmic optimization and mapping techniques.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Greenhouse Gas Mitigation through Advanced Nitrogen Removal Technology' under Horizon 2020.

assistant: **Concept**

Human activities have severe impacts on the biological carbon and nitrogen cycles. The most important consequences of these are global warming and water pollution. Wastewater treatment technology, in particular nitrogen removal systems, improved considerably in the last decade. The application of anaerobic ammonium oxidizing (anammox) bacteria in oxygen-limited granules has the potential to turn wastewater treatment plants into energy-efficient systems with minimal greenhouse gas emissions of carbon dioxide, nitrous oxide and methane. Recently, microorganisms that couple the anaerobic oxidation of methane to denitrification were discovered. An innovative integration of these microorganisms into partial nitritation-anammox systems for wastewater treatment offers an elegant and efficient solution to combat greenhouse gas emissions from wastewater treatment plants. The aim of the GREENT project is to determine nitrous oxide emissions from partial nitritation-anammox bioreactors and the parameters that govern these emissions, and to investigate the responsible pathways in molecular detail. Furthermore, I will explore the feasibility of an innovative bioreactor, which will remove ammonium and methane simultaneously through anammox and anaerobic methane-oxidizing microorganisms. This approach will turn the otherwise harmful methane into a resource for efficient nitrogen removal. These fundamental insights and technological advances will be achieved by a complimentary array of state-of-the-art methodology such as continuous culturing, stable isotope tracing and a combination of  -omics methods together with physiological experiments and detailed measurements at full-scale installations. The results of this proposal will be of paramount importance for the wastewater treatment s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Cryptography and Complexity', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Modern cryptography has deeply rooted connections with computational complexity theory and other areas of computer science. This proposal suggests to explore several {\em new connections} between questions in cryptography and questions from other domains, including computational complexity, coding theory, and even the natural sciences. The project is expected to broaden the impact of ideas from cryptography on other domains, and on the other hand to benefit cryptography by applying tools from other domains towards better solutions for central problems in cryptography.