RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Quantifying Atrial Fibrillation Burden to inform Screening, Treatment, and hEalth Policy' in the context of a Horizon Europe call.

assistant: **Objectives**

Atrial fibrillation (AF) affects every 3rd 55 year-old and causes severe death and severe morbidity, especially stroke and heart failure. AF consumes 2-3% of total healthcare cost in Europe. AF is currently diagnosed in a binary (yes/no) fashion. This has critical limitations, illustrated by low event rates in AF screening trials and in device-detected AF. This creates avoidable uncertainty and anxiety when implanted devices and consumer electronics detect short and rare episodes of AF in real-time. Quantification of AF burden and knowledge on its relation to outcomes can resolve this and harness the health opportunities of consumer-led AF detection. AF-B-STEP will define which AF burden affects health outcomes in patients with AF for implanted devices and intermittent rhythm monitors. This will improve clinical care and facilitate AF innovations.In AF-B-STEP, a public-private partnership, academia, industry, patients and payors work hand-in-glove with device, drug, and m-health industry. Integration of patient voices, health economics, an international external steering committee and of the European Medicines Agency and the FDA ensure high impact and rapid implementation. Multiple large, well-phenotyped, data sets containing AF burden and health outcomes from over 100,000 patients will be combined. This data set will be used to quantify AF burden and to define which AF burden contributes to stroke, heart failure, cardiovascular death and to patient-reported outcomes, cardiac and cognitive function. AF burden-reducing randomized trials will be analysed to validate these effects and to estimate actionable AF burden thresholds. We will define universally applicable standards for the reporting of AF burden by implanted devices and by consumer electronics. Key markers for l
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Design of polyPEPTIdes diblock copolymers as emulsifiers to produce safe, controlled and reliable novel stimuli-responsive nanoCAPSules for skin care applications', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

PeptiCaps aims at producing and validating a new family of stimuli-responsive nanocapsules able to encapsulate efficiently and protect specific active ingredients for skin care application. Those nanocapsules will be assembled by nanoemulsion technique using amphiphilic and biocompatible polypeptides diblock copolymers with one hydrophilic poly(ethylene glycol) block and one hydrophobic polypeptide block. Adjustment of the length of each block to finely tune the hydrophilic/Lipophilic balance of the macroemulsifier will allow the encapsulation of either hydrophobic or hydrophilic active ingredients. In addition, polypeptides block will be specifically designed to respond to changes in pH and the presence of enzyme occurring for the skin conditions targeted to allow a triggered release of the active ingredient. After scaling-up selected macroemulsifiers under GMP-like process, two manufacturing processes will be used for the production of the nanocapsules, i.e. high-pressure homogenizer and tubular flow contactor. The most promising process will be selected to produce selected nanocapsules. Physico-chemical properties and (eco)toxicity of the nanocapsules will be extensively characterised using techniques and protocols recommended by the EU Cosmetic regulation to establish their risk and safety assessment. The advantages of safe nanocapsules from PeptiCaps will be demonstrated on validated relevant skin models for each application. All results obtained will be gathered to constitute a Dossier for the validation of the nanocapsules as cosmetic product by the authorities. In addition, PeptiCaps will actively participate to the standardization for nano-safety by developing software to predict the toxicity of nanomaterials (CORAL). Finally, a business plan will be elaborated
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Developing a European Framework for the generation of guarantees of origin for green hydrogen' (CertifHy), addressing dissemination and exploitation.

assistant: **Impact**

The development of hydrogen as an energy carrier will be dependent upon the capacity of the market to offer low-carbon or carbon-free hydrogen to end-users and consumers. However, the production of green hydrogen and its consumption will most likely be unbundled in order to optimize its transportation and distribution, while enabling cost adequate pricing for green hydrogen. This implies that a robust system of Guarantee of Origin for green hydrogen will be needed, in order for final customers to buy low-carbon hydrogen in full transparency. The objectives of the CertifHy project are to assess the necessary market and regulatory conditions, develop the complete design and initiate a unique European framework for green hydrogen guarantees of origin. The project will be carried out in consultation with a broad range of relevant stakeholders from all over Europe, including hydrogen producers, traders and customers. Ultimately the CertifHy guarantee of origin scheme will facilitate the penetration of green hydrogen throughout Europe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'New directions in market design' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Recent years have seen an increasing use of theoretically grounded market designs to solve important real-life matching problems. A key factor for these practical accomplishments is that matching theory has been successful in developing centralized mechanisms that are (1) stable, that is, give agents no incentive to contract outside the mechanism, and (2) strategy-proof for a significant subset of participants, that is, provide these economic agents with strong incentives to reveal their true preferences over available matching opportunities to the mechanism. This project aims to make significant progress towards solving two of the most important open questions in this research area.First, several high-profile practical applications have shown that there is scope for designing stable and strategy-proof mechanisms even when the weakest known sufficient conditions for the existence of such a mechanism are not satisfied. I aim to provide a complete characterization of the circumstances under which stability and strategy-proofness can be achieved by means of a centralized matching mechanism. Apart from providing a unifying explanation for all existing applications, the hoped for results can help to identify new real-world problems to which matching theory can be applied.Second, full centralization is not feasible for many important real-life matching markets. Decentralized markets often suffer from congestion, which induces strong incentives for participants to condition their behavior on available statistics about past market conditions. In the second part of this project, I plan to study the dynamic consequences of individual learning in decentralized matching markets using theoretical, empirical, and experimental methods. The key motivating application is a decentralized
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Taming dynamic complex media for imaging, communications and photonic computing' (ModeMixer) targeting Horizon Europe.

assistant: **Abstract**

The turbulent atmosphere, flexible optical fibres, and living tissue, are all examples of opaque materials that change in time. Light propagating through these moving complex media is subject to intricate dynamic scattering effects: transmitted optical fields are unrecognisably distorted in space and time. Such phenomena permeate real-world imaging and communications technologies. They prevent microscopy deep into living tissue and hinder both free-space and fibre-optic data transmission.My vision is the realisation of optical technology that automatically configures itself to dynamically cloak unwanted scattering effects of any opaque medium it is coupled to  making it possible to look through to an unobstructed view of scenes on the other side. The multimodal nature of this challenge calls for a raft of new sensing and light control techniques. The aim of this proposal is to develop these technologies.I have begun to take some of the first experimental steps to achieve these goals: I have developed a new form of adaptive optics that suppresses temporal rather than spatial light distortion. I have also implemented prototype adaptive optical inverters, capable of all-optically unscrambling light propagation through multimode optical fibres (MMFs) supporting ~30 modes. My project builds on these concepts, and is delivered through 3 overarching objectives:1. Real-time monitoring of spatio-temporal scattering in dynamic complex media: Creating dynamic digital twins of complex media that evolve in real-time.2. All-optically unscrambling dynamically scattered light: Building new types of programmable optical circuit driven by our digital twins to cloak spatio-temporal scattering effects.3. Applications: reversing the scattering effects of MMFs and atmospheric turbulence; ena
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Risks associated with tilletia indica, the newlylisted eu quarantine pathogen, the cause of karnal bunt of wheat' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

This project will determine risks posed to eu wheat by tilletia indica, the cause of karnal bunt. T. Indica does not occur in europe but is intercepted on wheat imports. It threatens wheat quality, yield and exports. Legislation to protect eu wheat was enforced by the ec in 1997 based on a theoretical pest risk analysis (pra). International debate has questioned the justification for legislation, implying such policies are trade-restrictive. Research will be undertaken to develop a more accurate pra for t. Indica. Modelling & geographical information systems will determine areas at risk; a socio-economic model will determine the risks this & related pathogens pose. A pra based on scientific experimentation will be produced which can be used internationally by policy makers to reevaluate legislation for t. Indica. A risk management plan will be developed for europe. The international pra process will be developed for plant pathogens.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Behavioral and Policy Implications of Rational Inattention' (INATTENTION) under Horizon 2020.

assistant: **Objectives**

This proposal outlines agenda which aims to improve our understanding of policies in environments with cognitively limited agents. It seeks to extend and apply the theory of rational inattention developed in macroeconomics. Citizens are inattentive to details of tax codes, government bureaucrats cannot inspect all data about people in need, and voters are highly uninformed about politicians’ campaign platforms. The agenda is specifically targeted at applications where human inability to digest all available information has strong implications for public policy formation. It falls into three broad parts.First (macroeconomics), the proposed research will develop a new model of risk-sharing in a typical modern-macro setting with heterogeneous agents.  Instead of incentive constraints, the imperfections will be driven by the government’s or citizens’ inability to process all available information. What are the properties of the resulting system of redistribution? Why do taxes often take a simple form? Can minorities be left behind because they attract less of the government’s attention? Second (behavioral economics), it will extend the rational inattention theory to model how agents simplify multidimensional features of the environment. Among many applications, the theory is likely to provide an alternative explanation for mental accounting, when people have separate budgets for different types of expenditures (critical to consumption decisions, especially of the poor), and for salience of different elements of the tax code.         Third (political economy), it will develop a unified framework to study implications of voters’ rational inattention (selective ignorance) for the outcomes of political processes, such as for popular demand for misguided policies, public good pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Terahertz Antennas with Self-amplified Spontaneous Emission'.

assistant: **Concept**

The project aims at studying the feasibility of Terahertz range emitters, with two main objectives:OB.1 – to investigate novel principles for nanoantennas, based on quantum effects enabling self-amplified emission in the THz range;OB.2 – to create a network of competencies on quantum and nanoelectronics, which includes academic and non-academic players, sharing knowledge and expertise retained by the partners. Several types of nanostructured materials will be investigated, such as graphene nanoribbons and graphene/polymer sandwiches, with embedded mesoscopic structures, or atomic chains (e.g., transition metals dichalcogenides and graphene dots and their chains) with interatomic coupling. First, new promising physical mechanisms will be studied, enabling the excitation of mesoscopic structures via shot noise, Rabi and Rabi-Bloch oscillations, and direct interband THz transitions induced by optical excitation. Then, new effective methods for mesoscopic systems will be developed, based on integral formulations that overcome the limits of the methods available so far. Finally, the project will design and implement specific experiments with the aim of observing and demonstrating the proposed physical mechanisms, and of providing proof-of-concept of the proposed THz devices. The final goal is that of bringing these novel solutions from Basic principles and Technology concept (TRL1-2) to experimental critical function and characteristic proof of concept (TRL3). A strong training and dissemination activity will be carried out, aimed at sharing competencies and expertise. Special emphasis is to be given to the interactions between theoretical and experimentalist Academic partners. The partners will transfer each others competencies and know-how in fields such as nanotechnology
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Natural killer cell-mediated anti-viral and anti-tumour defence and therapy: Integrated research training in molecular medicine, bioinformatics and issues of patent application and the SME biotech business', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

The development of novel technologies of immuno-therapies holds great promise for potential future treatment of hitherto difficult to cure viral diseases and tumours. It is to be anticipated that such technologies will provide the physician with potent novel therapies and will be the basis for the establishment and growth of new biotech SMEs. This proposal suggests therefore to combine research work on natural killer (NK) cell immune defences and therapies, with training in bio-informatics and issues of patent applications and management of the biotech business.The research part will deal with mechanisms of the innate immune defence used to control viral infections and tumours. It will focus on receptors used by NK and some myeloid cells to interact with surf ace structures exposed by virally infected and/or tumour cells. Firstly, it will investigate the mechanisms developed by viruses and tumours to avoid or subvert immune defences. In this respect viruses have evolved a large number of genes, which function to interfere with the expression of ligands that could be used by NK cells to trace infected cells. Similarly, many of the same or related target molecules can be found down regulated in tumour cells. Secondly, we will use the molecules recognized by receptors on NK and myeloid cells to develop technologies to boost immune reactions.This will be done by:i) by specific reagents directing immune cells to the infected/malignant target cells andii) by genetically engineering NK cells to provide them with increased activities.We intend to train the students of this RTN in all techniques of immuno-technology including wider aspects of molecular medicine by enrolling them in the established MD/PhD programs of the respective Universities. An exchange of students between th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Modeling and controlling traffic congestion and propagation in large-scale urban multimodal networks' (METAFERW).

assistant: **Concept**

As cities grow rapidly and more people through different modes compete for limited urban road infrastructure to travel, it is important to manage traffic space to improve accessibility for travelers. This project tackles the problem of modeling and optimization in large-scale congested traffic networks with an aggregated realistic representation of dynamics and route choice and multiple modes of transport. This is a highly motivating problem both because of the socio-economic influence of congestion and the challenges embedded in the optimization framework and the modeling aspects. Currently most optimization methods for transport networks (i) are suited for toy networks with simplified dynamics that are far from real-sized networks,  (ii) apply decentralized control, which is not appropriate for heterogeneously loaded networks, (iii) investigate engineering solutions through micro-simulation models and scenario analysis that make the problem intractable in real time, (iv) are not considering interactions and conflicts between transport modes (car, bus, delivery vehicle). This problem is even more challenging if one considers that transportation networks have a hierarchical structure with freeways and urban roads with mixed or separated traffic (e.g. bus-only lanes), that have dissimilar traffic flow dynamics. Lack of coordination among the jurisdictions during traffic operations or limited means of traffic data monitoring and communication can impede such mixed traffic network ideal goal. Traditionally, choices of people in transportation networks are based on equilibrium conditions with small variations.The huge amount of datasets (including thousands of GPS data from taxis, cars and buses and road detector data from heavily populated cities worldwide) can provide a u