RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Regulation of Cullin based E3 ligases by the ubiquitin-like protein Nedd8/Rub1p' in the context of a Sixth Framework call.

assistant: **Objectives**

Targeted protein degradation has emerged as a major regulator of many essential cellular processes. Consistent with these findings, a wide variety of human diseases have been linked to defects in the cells protein degradation machinery. Ubiquitin-dependent protein degradation has been identified as the major player governing this process. Ubiquitin is a small polypeptide that gets linked to other proteins through the actions of an enzymatic cascade consisting of an E1 activating- and E2 conjugating enzyme, as well as an E3 ubiquitin ligase. Once proteins are tagged with a chain of ubiquitin molecules, they are degraded by the 26S proteasome.The E3 ligases are of significant importance for this process, since they recognize the substrate prior to ubiquitination. Here I propose to study one subclass of E3 enzymes, the multi-subunit SCF E3 ubiquitin ligase complexes. One core component of these complexes are cullin proteins, which serve as a scaffold for the recruitment of E2-bound ubiquitin and the substrate by other ligase subunits. Additionally, positive regulation of E3 ligase activity is achieved by modifying this cullin subunit with the ubiquitin-like molecule Nedd8/Rub1p (neddylation).SCF ubiquitin ligases and Nedd8 modification of the cullin sub unit are highly conserved throughout evolution, including in humans. While the importance of neddylation has been demonstrated across species, the precise molecular mechanisms that regulate this process remain elusive. I have identified a novel and conserved protein required for cullin modification in budding yeast and C. elegans. My preliminary data suggests that this protein is a component of the Nedd8 modification machinery and might possibly act as a ligase for Nedd8. The goal of this proposal is to further characterize
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'PASSAGE'.

assistant: **Objectives**

The PASSAGE project aims to develop a “Capability Management Platform” providing Textile and clothing industrial associations with a set of validated products and services enabling their affiliated SMEs to efficiently manage the existing know-how and skills together with new competences taking the technological evolution into consideration. The objective of the platform is to make knowledge-based web-services available to the SMEs, taking a holistic view on the whole supply chain, to diagnose, forecast and manage know-how and competence needs.  Such a platform will offer a method, tools and related guidelines dedicated to the diagnostic of future critical know-how shortages and the definition of preventive actions to face them based on an anticipative human resource management methodology including: - An integrated methodology and related product-service for anticipating new/future know-how required to master technological evolutions.  - A method and related guidelines dedicated to the diagnostic of the critical know-how detained by SMEs in a given Region/Job/Work position/Competence and enabling the anticipation of possible competence shortages (illness, retirement…).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'A novel, low-pressure, cost-effective system for introducing ozone to industrial water systems.' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

The control of bacteria in industrial water systems is essential for their safe and economic operation. Control is also needed to protect public health where water is used in food preparation , surface cleaning or in public buildings. The use of currently available biocides is being questioned on health and environmental grounds. Ozone is accepted as a 'safe' biocide but cannot be readily used in 'small' systems as current methods of production are both expensive to buy and operate. We propose, through co-operative research, to define the operational parameters of a novel patented ozone generation system which will enable it to be used safely and economically in such systems; to develop a prototype and to assess the effectiveness in a range of applications.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Biological decontamination of surfaces using plasmas discharges' under Sixth Framework.

assistant: **Concept**

The interaction of specific biomolecules like endotoxins or certain proteins with organisms can be a major cause of diseases. Prominent examples are pyrogenes - lipopolysacharides (LPS) and lipoteichoic acids (LTA) -, which cause fever in human body and ar e potentially lethal after injection. In some cases the secondary or tertiary structure of proteins is responsible for their biological properties. Important example is PrP (prion). Some contaminated object such as a surface (e.g. medical devices, accessor ies, work surface or tissue) cannot be decontaminated with current sterilisation practices at all or only with inducing major damage to the substrate or tissue itself. An applicable innovative technology for the inactivation of pathogenic biomolecules is, therefore, urgently desired. It is proposed to exploit the feasibility of plasma discharges as decontamination device for pathogenic biomolecules. Emerging species from the plasma discharge interact individually as well as simultaneously with the biomolecu les. It is expected that this reactive particle flux is able to induce alteration and inactivation of biomolecules. This is addressed in a combined approach using low and high pressure plasma discharges. Different characteristic biomolecules are exposed to the plasmas and the changes induced are monitored. In a second step, the inactivation of resistant bacterial endospores is explored. The potential applications are in the field of surface decontamination of medical objects and surfaces as well as control of a biological environment. The results of the research will have also an important impact in the field of security and protection of citizens in front of bioterrorism. For instance, atmospheric plasma sources will be developed and validated to serve as a deco
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Fuel Cell Ionomers from Durable Aromatic Hydrocarbon Polymers of Intrinsic Microporosity' (PIMIonFuelCell) targeting Horizon Europe.

assistant: **Abstract**

Vehicular transportation is responsible for a third of greenhouse gas emissions globally. Hydrogen fuel cells, comprising of a proton exchange membrane (PEM) coated with catalyst layers (CLs) and sandwiched between gas diffusion layers, generate electrical energy with high efficiency and zero emission. The concern regarding a potential ban by the European Union on the use of per- and polyfluoroalkyl-type forever chemicals that are currently used as PEMs and CL ionomers prompts us to seek sustainable alternatives, such as aromatic hydrocarbons (AH). Significant progress has been made to use AHs as PEMs, due to their excellent thermal stability and eco-friendly synthesis. However, presently the specific adsorption of aromatic constituents on the noble metal catalyst and low gas permeability in the CL causes a performance penalty, thus aggravating the use of AHs as catalyst ionomer.The aim of this project is to address these issues by developing a new class of catalyst ionomers based on AH polymers with intrinsic microporosity (PIMs). AH PIMs are expected to improve FC performance: as highly gas permeable ionomer in the CL, they facilitate chemical reactions and improve interfacial compatibility between CLs and PEM.Using chemically durable polyphenylenes as scaffold we propose to synthesize a range of AH PIMs with enhanced gas permeability and chemical durability (objective 1-2, University of Yamanashi). Catalyst ink formulations will be prepared and coated on both sides of best-in-class AH-based PEMs to obtain catalyst coated membranes (CCMs) with optimized morphology, electrochemical surface area, electrochemical activity and ionic conductivity (objective 3-4). Finally, the performance and durability of the novel CCMs will be evaluated in the single fuel cell at Universi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'RFID-based feeder for giving dairy cows access to additional mineral supplements in a restricted and targeted way during the critical transition period of the lactation cycle' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

MicroFeeder Pitstop PLUS is a market disruptive invention that responds to a huge need in EU and globally for a method for giving dairy cows in the critical transition period of the lactation extra minerals, trace elements, vitamins and other feed additives in a targeted and restricted way. Total Mixed Rations (TMR) has globally become the dominating feeding system, but cows in the critical transition period, starting 2-3 weeks before calving and lasting until around 100 days after calving, are in relation to their nutritive needs not able to eat sufficient amounts of their TMR, which is their sole source of minerals and vitamins. The result is low immune status and increase of incidences of diseases related with legs, cloves and digestion. Cows that do not recover, becomes so-called “loser cows” with a much elevated mortality rate. The described development is not only compromising ethical standards for food production, it also causes increasing economic losses related to suppressed production, fertility and health, which also is an animal welfare issue, furthermore with adverse environment, health and climate effects. The Pitstop PLUS feeder is equipped with electronic components, such as RFID based technology to identify the cows, dosing devices and advanced MESH communication. The feeder is managed through a web interface and designed for mounting on a wall, thus not taking up space in the stable. The project will stimulate the innovation capacity of enAgro and support its long-term strategy to consolidate its position in the market segment of mineral feeders via a wider variety of unique sales products, and in this way promote an organic company growth along with the building up of more specialised expertise through staff with diversified competences. Preliminary b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'European Coordinated Research on Long-term ICT and ICT-based Scientific and Technological Challenges' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

CHIST-ERA is a network of research funding organisations in Europe and beyond with programmes in Information and Communication Science and Technology (ICST), at the intersection of the FET and the ICT and ICT-based domains. CHIST-ERA IV ERA-NET aims at supporting transnational research projects addressing long-term scientific challenges in the domain of ICT or at the interface between ICT and other domains. It also fosters the maturation of the corresponding research topics and the structuration of the corresponding communities. Another goal is to encourage Open Science best practices, raise awarness about responsible Research and Innovation and support the exploitation of the research projects funded by CHIST-ERA by the industry. In the framework of CHIST-ERA IV, 6 joint transnational calls are planned (the Calls 2019, 2020, 2021, 2022, 2023 et ORD). The two topics for the Call 2019 are ""Explainable Machine Learning-based Artificial Intelligence"" and ""Novel Computational Approaches for Environmental Sustainability"".""


**Keywords:** FET, ICT, ERA-NET, Joint Transnational Call, use-inspired research, future and emerging technologies,strategic research agenda, FET Proactive, FET Flagships, Open Science
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Massive star formation with Interferometers: Research with ALMA'.

assistant: **Objectives**

Massive stars – with masses larger than 8Mo – are rare in the Galaxy. However, they dominate the energetics of galaxies, shaping their structure and impacting on their evolution. The formation of massive stars has recently become a hot topic in Astrophysics thanks to the advent of astronomical facilities operating at infrared (IR) wavelengths. These facilities have revealed that massive stars are formed in filamentary structures viewed as shadows against the bright IR Galactic background (Infrared-Dark Clouds or IRDCs). When observed at higher angular resolution with millimeter (mm) interferometers, these structures show dense condensations (clumps) that fragment into smaller cores (IRDC cores and Hot cores). Much progress has been done in the past 10 years to understand the physical processes involved in this empirical evolutionary sequence. However, several questions still remain unanswered. MIRA will observationally cover all stages of early massive star birth to establish the mechanisms that lead to the formation of massive stars. This research will continue the work started by the applicant with the Submillimeter Array interferometer (SMA, USA), and will make extensive use of the new international interferometric facility, the Atacama Large Millimeter Array (ALMA). The SMA, as a pioneer instrument in sub-mm astronomy, has served as a platform for the development of ALMA. At present, it is strategically important for Europe to have highly qualified astronomers with expertise in sub-mm interferometry, who can fully exploit the unprecedented capabilities of ALMA. MIRA will be carried out at the European Southern Observatory (ESO), which leads the European contribution to the construction of ALMA. This fellowship will allow the applicant not only to transfer the knowle
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'INNOVATIVE SCO2-BASED HEAT REMOVAL TECHNOLOGY FOR AN INCREASED LEVEL OF SAFETY OF NUCLEAR POWER PLANTS' to be submitted under Horizon 2020.

assistant: **Abstract**

The main aim of the sCO2-4-NPP is to bring an innovative technology based on supercritical CO2 (sCO2) for heat removal in nuclear power plants (NPPs) closer to the market. sCO2-4-NPP builds on results of the previous H2020 sCO2-HeRo project, where the technology was first developed and brought to TRL3. The sCO2-4-NPP technology will be a backup cooling system, attached to the principal steam-based cooling system, which will considerably delay or eliminate the need for human intervention (>72 hours) in case of accidents such as StationBlackOuts, thus replying to the need for increased safety in NPPs. Thanks to the compact size and modularity of the system, it can be retrofitted into existing NPPs but also included in future NPPs under development. Through a close collaboration between major industrial actors and highly-skilled academic institutions, the sCO2-4-NPP partners will bring the full system to TRL5 and parts of it to TRL7 by carrying out experiments, simulations, design, upscaling and validation of the technology in a real NPP PWR simulator. Regulatory requirements will be considered in the conceptual design of components and the system architecture to increase the chances of acceptance by European nuclear safety authorities and speed up the road to the market. Detailed technical, regulatory, financial and marketing roadmaps will be developed for bringing the technology to industrial use (TRL 9) after the project. The sCO2-4-NPP technology will increase NPP safety, decrease the plant overall environmental footprint and potentially lower costs for energy consumption, thus increasing the competitiveness of European NPP operators.


**Keywords:** NPP safety, LWR, supercritical carbon dioxide, sCO2 heat removal system, decay heat removal, roadmaps to market, validat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Characterisation and manipulation of the microbial ecosystem in minimally processed fruit juices for improved quality and safety' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The ecology of pathogenic and spoilage micro-organisms in minimally processed fruit juices will be studied using classical and molecular tools with the ultimate aim of facilitating the development of novel microbial control measures for ensuring the quality and safety of these products.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Integrated Components for Complexity Control in affordable electrified cars' (3Ccar).

assistant: **Concept**

The 3Ccar project will provide highly integrated ECS Components for Complexity Control in thereby affordable electrified cars. The new semiconductors for Complexity management (Control, reduction) will offer the next level of energy efficiency in transportation systems.3Ccar’s impact is maximizing pragmatic strategy: Use semiconductor technology innovations to manage functionality & complexity increase. This leads also to cheaper, efficient, robust, comfortable, reliable and usable automotive systems. This strengthens Europe as a whole (OEM, Tier1, Semiconductor) generating economic growth and new jobs in Europe.The impact of 3Ccar is driven vertically by innovations and horizontally enabling growth and deployment in the industry based on what we see as European Values. We recognized that European engineers develop for highest efficiency, convergence and manageable complexity. Our society appreciates long life products to avoid waste. 50 partners and 55 Mio€ budget give the mass for innovative products such as functional integrated powertrains, smart battery cells with unique selling features allowing Europe to advance to global leadership. An important feature of the project has been the recognition and exploitation of synergies with other EV projects, enabling fast innovation cycles between such aligned projects.With 55 Mio€ budget and 10 b€ impact the R&D expenditure ratio is 200 which is 10x higher than the semiconductor average and corresponds to very strong innovation potential which will be translated into automotive and semiconductor industry. The technologies developed in 3Ccar will be commercialized all over the world while giving advantages to Europe’s OEMs willing to manufacture in Europe. 3Ccar will be involved in standardization needed to ensure that large