RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Archaeometric Analysis of Maltese Prehistoric Pottery', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Ceramic pots are an enduring and resilient document of ancient culture. Often specific to time and place, they are a valuable record which can enlighten our understanding of ancient chronologies, aesthetics, technologies, trade networks and cultural ties. The Maltese islands have a particularly rich, diverse and dynamic ceramic assemblage covering the entire prehistoric period. While the later ceramic assemblages of Bronze Age Malta have received considerable study over the past decade, little archaeometric research has been conducted on the earlier ceramic phases. MaltaPot will address this by exploring the emergence of the earliest prehistoric ceramic phases (namely Għar Dalam, Skorba and Żebbuġ 5000-3800BC) through a series of multi-disciplinary laboratory-based methods including typological analysis (3D laser scanning and digital classification software) and material studies (optical microscopy, LIBS, XRF and XRD). Findings from this project will dramatically increase understanding of the earliest settlers on the Maltese islands and it will also have wider implications for our understanding of Mediterranean archaeology during this important period of Neolithic colonisation by exploring cultural links through typological, technological and material studies. MaltaPot will develop new methodologies for the archival and analysis of prehistoric ceramic assemblages and also advance new methods of displaying and dissemination of results to both the wider public and academics. The fellowship will contribute to the researcher’s career development through the acquisition of advanced skills in archaeometric approaches to ceramic analysis as well as developing skills within the heritage sector through a series of events designed to disseminate her results to the wider public. T
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'IMAGING FOR PATIENT BENEFIT IN ARTHRITIS' (AutoPiX), addressing dissemination and exploitation.

assistant: **Impact**

Patients at risk or diagnosed with arthritis are constantly assessed by innovative imaging techniques to document the onset or progression of their disease. However, despite their impressive abundance and resolution, these images lack the analysis and interpretation tools necessary to deliver unbiased and precise diagnosis, monitoring and prognosis to the patients. Additionally, some key advanced imaging methodologies such as ultrasound are hardly accessible to most of patients, urging improvements of more accessible imaging methods.The AutoPiX project is an ambitious international multi-stakeholder effort led jointly and synergistically by academic and industry partners to achieve breakthroughs in both the applicability and harnessing of imaging technologies for the benefit of patients by creating new powerful analysis and decision tools.We will first generate tools to transform unstructured images into quantitative biomarkers using artificial intelligence (AI) and machine learning (ML) models, and validate them clinically for their diagnosis, monitoring and prognosis power. This will considerably increase the utility of imaging biomarkers for arthritis and bring them to the same level as laboratory biomarkers.In parallel we will develop accessible imaging strategies such as remote monitoring and robotic-powered point-of-care ultrasound exams for patients to mitigate the often-observed shortage of qualified personnel in real world settings. To achieve this, we will improve the precision and interpretability of these methods and further validate them with clinical, molecular and histological analyses.Our consortium is built on multi-disciplinarity and the constant synergistic interaction of all the actors of arthritis care: rheumatologists, radiologists, patients, resea
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Development of a continuous measuring method for adsordable organically bound halogens AOX in waters'.

assistant: **Innovation**

AOX Adsorbable Organically bound Halogens are considered to be a very dangerous group of materials in that they produce toxic mutagenic and carcinogenic effects and some of them have a strong bioaccumulation property in fat containing tissues. However, to date no fast automatic device for the monitoring of AOX exists in the market. The present project aims to develop a monitoring technology to keep track of the concentration of adsordable AOX present in water streams.Common sources of AOX are industrial processes urban and agricultural activities human activities and even natural phenomena Currently available methods to measure the AOX components in water involve arduous laboratory methods which prove slow and entail difficult and complex procedures Hence such measurement needs to be carried out in specialised laboratories by trained staff rendering any automatic and or continuous measurement of AOX simply unfeasible and drastically reducing the number of analysis performed.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'APPLICATION OF HAMLET TOOLS TO EMBEDDED MEDICAL DESIGN' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

The development of parallel computing environments and parallel algorithms for medical images require a high-level professional software engineering environment supporting each phase of a multi-transputer system design. Such a software environment is the HAMLET tool set, developed within ESPRIT project 6290.The main objective of the AHMED project is to demonstrate the industrial applicability of the HAMLET tool set. HAMLET was developed to support the design of transputer-based embedded systems. Within the current project we intend to assess the applicability of HAMLET in general, as well as in the particular case of the urine analyser Seditron, developed by ASK Ltd., that is a multi-transputer based instrument.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Super-resolution imaging to uncover microRNA control of astrocytes in epilepsy' in the context of a Horizon 2020 call.

assistant: **Objectives**

This Horizon2020 – Marie Sklodowska Curie Actions – Individual Fellowship grant proposal focuses on exploring mechanisms controlling the structure of support cells (astrocytes) in the brain that promote hyper-excitable neuronal networks and underlie common, chronic neurologic disorders such as epilepsy. My research builds on emerging data showing the molecular machinery for microRNAs - short non-coding RNAs that regulate gene expression post-transcriptionally by targeting mRNAs - is present locally, within astrocyte processes. For this purpose, I will employ for the first time super-resolution microscopy to visualise astrocyte processes and microRNAs in rodent and human brain. I will then target candidate microRNAs to influence astrocyte morphology, and increase local translation of neurotransmitter and ion channels in astrocytic processes. In turn, this allows the clearing of excess glutamate and potassium from the synaptic cleft and hence prevents synchronous neuronal discharges that generate seizures. During the fellowship, I will acquire new research skills in modelling epilepsy and through training and secondments, where I will visualise locally produced proteins in astrocyte processes after microRNA targeting. The ground-breaking nature of the project will enhance my creative and innovative potential. With advanced training and international mobility, the fellowship will help me to diversify my scientific and non-scientific skills needed to help me reach my career goal of transitioning into an independent principal investigator in molecular imaging and translational neuroscience focused on astrocyte biology and pathophysiology. These findings will have strong therapeutic relevance, offering a novel strategy for seizure-suppressive or disease-modifying actions via
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The nuclear pore permeability barrier – physical concepts and a biosynthetic approach to understand and exploit the unique selectivity of a natural macromolecular sieve' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Nuclear pore complexes (NPCs) are the exclusive gate of entry/exit of macromolecules into and out of the nucleus of living cells. They exhibit a unique selectivity in transport, with respect to size and molecular species: very small molecules can diffuse efficiently through the pore, while larger objects are delayed/blocked unless they are bound to specialized proteins, so called nuclear transport receptors (NTRs). The permeability barrier and its selectivity arise from an assembly of protein domains that are rich in phenylalanine-glycine repeats (FG repeat domains). These domains are natively unfolded and grafted at high density to the NPC channel walls. NTRs can interact with the FG repeat domains, thereby facilitating translocation of NTR-bound cargo.The supramolecular organization of the nuclear pore permeability barrier and the mechanism behind selective transport remain insufficiently understood. Our goal is to understand the relation between the organizational and dynamic features of FG-nucleoporin assemblies, their physicochemical properties, and the resulting biological functions. Using an approach that combines tailor-made biomimetic in vitro model systems, surface-sensitive in situ analysis techniques, and polymer physics theory, we will quantitatively study these relationships on the supramolecular level, a level that – for this type of assemblies – is hardly accessible with conventional biological and biophysical approaches. The model systems will be well-defined allowing tight control over composition and supramolecular structure. In a second step, we will apply the obtained knowledge and construct a biosynthetic in vitro system that performs active, directed macromolecular transport.If successful, this highly interdisciplinary project will greatly increas
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'MRI analysis tool for early detection of dementia' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Worldwide due to population ageing there will be 75 million patients with Alzheimer's disease by 2030. Alzheimer's is a disease described by accelerated brain ageing which leads to decline in both memory and cognitive skills, thus affecting everyday activities of those suffering. On average over 60% of patients do not receive a diagnosis and average cost of misdiagnosis is estimated to be over 2K €. Existing screening and early diagnostics methods lack speed and accuracy, are not automated enough, and detect only already existing symptoms when it is late for prevention. At Neurosalience we develop a software for assessing brain ageing for early detection of Alzheimer's disease from low-resolution MRI and CT scans. Measuring subject’s brain age and extracting important features for making a prediction are used to assess the risk of Alzheimer's disease. The tool determines whether patient has Alzheimer's along with its stage and type of dementia. We aim at supplying healthcare providers with a more accurate, cheaper and faster early diagnostic tool for Alzheimer's disease. The tool allows decreasing patient-related costs and improving the quality of life of patients. The tool is first in the world to be capable of processing even low-resolution MRI data and providing interpretable results over whole brain. With the support of the Women TechEU programme we will boost the market readiness of the Neurosalience tool by developing the project both from business and regulatory perspectives. For this purpose, we plan to develop a pricing model for the tool, improve deep learning models used in the product and prepare all the documentation along with quality management system required for regulatory approval. We would benefit from the Women TechEU services of mentoring and coachi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Non-Invasive Imaging of Nanoscale Electronic Transport' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Electronic transport in nanostructures and thin films shows a rich variety of physical effects that have been fundamental to the development of modern electronics and communication devices. The standard method for investigating electronic transport – resistance measurements – does not provide any information on the nanoscale current distribution in such structures. The lack of spatial information is unfortunate, because the current distribution plays a key role in many intriguing physical phenomena. Having a technique at hand that could simply look at nanoscale current flow would be immensely valuable.In this project we propose to exploit sensitive magnetic microscopy to directly access the current distribution in nanostructures with ~15nm spatial resolution. Our approach is based on the recent technique of scanning diamond magnetometry (SDM), a scanned-probe method that utilizes a single spin in a diamond tip as a high-resolution sensor of magnetic field. Conceived in 2008 by the PI, SDM exploits quantum metrology to achieve very high sensitivities, and has recently enabled a breakthrough in the passive analysis of magnetic surfaces. Our proposal has three objectives: (i) Lay the instrumental and conceptual groundwork required for imaging tiny (<10nA) current variations in two-dimensional conductors. (ii) Demonstrate imaging of a variety of mesoscopic transport features on a well-established model system: Mono- and bilayer graphene. (iii) Explore the potential of our technique for probing electronic properties beyond transport, like phase transitions and photoexcitation.Together, our experiments are designed to establish a powerful new technology for imaging current distributions non-invasively and with nanometer spatial resolution. This capability will provide the uni
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'The control of ice nucleation (IceControl)' (IceControl).

assistant: **Innovation**

The control of ice nucleation is key to improving the efficacy of a wide range of industrial processes, but effective methods of controlling ice nucleation have been remarkably elusive. In many manufacturing processes, from cryo-storage of stem cells for regenerative medicine, making ice cream or even freeze concentration of alcoholic beverages, the aqueous medium will supercool well below its equilibrium melting point before freezing. Controlling this nucleation processes is critical, for example, in the cryopreservation of cells excessive supercooling usually results in their death. Hence, there is a demand for materials which catalyse ice formation and are compatible with a range of industrial processes.In my ERC Starting grant we made a major new discovery concerning an important class of ice nucleating particles for clouds in the Earth's atmosphere (Atkinson et al., Nature, 2013). We showed that a minor component of many desert soils, feldspars, are very effective ice nucleants; this was surprising since it was previously thought that the clay minerals were the most efficient. This new knowledge offers a new route to controlling ice nucleation in many applications.The initial focus will be on a range of applications in cryopreservation since it is these applications I am well positioned to exploit, but also represent a significant high value and growing market. Many other opportunities exist and during the course of IceControl we will explore the feasibility of the application of this technology in areas such as freeze drying and ice cream production. The specific tasks in IceControl will be optimising delivery of feldspar, manufacture of feldspar, assessing regulatory issues, trials and testing, dissemination of results, technical marketing, assessment of signific
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Dating Plastid Endosymbiosis and Diversification in Eukaryotic Algae'.

assistant: **Innovation**

Eukaryotic algae evolutionary history is still fairly unknown. Thanks to state-of-the-art evolutionary models, next-gen sequencing and high computational capabilities, we are going to shed some light on the matter.Corallinales (red algae) and Dasycladales (green algae) are two extant living groups of calcareous algae with a rich fossil record (~140 and ~500 myr respectively). The lack of sufficient molecular data for these groups makes impossible to use such species in eukaryotic phylogeny and dating studies. This project has been planed to cover 2 objectives or evolutionary questions:The 1st objective aims 1) to generate de novo transcriptomic data for about 10 species corresponding to different Corallinales and Dasycladales lineages in order to perform phylogenomic analyses with 2 established datasets (one of 200 nuclear-coding plastid markers, and the other with 258 non-plastid genes) and the broadest possible eukaryotic taxonomic sampling; and 2) to perform molecular clock analyses using known fossil calibrations and hence provide robust divergence times for the whole eukaryotic tree but focusing on primary and secondary plastid endosymbiotic acquisitions. For both post- phylogenomic analyses (dating and divergence steps), already established collaborations will ensure proper method implementation.Using the results from the first objective, the 2nd one aims 1) to track history of plastid evolution (plastid-based dataset) comparing it with deep eukaryotic speciation events (non-plastid marker tree); and 2) to estimate diversification rates in distinct photosynthetic lineages in order to find if rate shifts correlate among them.AlgDates will allow us to establish the order, timing and correlation of events in such deep evolutionary transitions, but the knowledge acqui
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Growth and Diversification in the Presence of Industry Linkages' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

This project investigates the growth and diversification patterns of countries in the presence of industry linkages in four separate but complementary objectives. In the fırst objective, the consequences of the linkages will be captured through the observed pattern of industries throughout countries and an economic micro-foundation will be provided using trade models. In the second objective, the diversification pattern and speed of countries will be related to the country level and product level quality measures. In the third one, temporal aspect of the trade data will be used and the effects of the spillovers will be analyzed using vector autoregressive models. Finally, in the fourth objective, effects of one specific type of spillover, namely the Input-Output linkages, will be explored both theoretically and empirically.The Experienced Researcher intends to build a successful academic career and impacting the decisions of policymakers within Turkey and Europe. This fellowship will enable Dr. Yildirim to embark on such a journey in a suitable environment provided by Koç University. The fellowship will complement Dr. Yildirim’s interdisciplinary background and he will also have the opportunity to establish himself in the field of economics.