RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Signal Transduction in Organic Materials' (STORM).

assistant: **Innovation**

It is the overall aim of this project to use responsive catalysts to introduce signal transduction cascades in soft materials, enabling autonomous, programmable and amplified response of soft materials to chemical signals from their environment. 'Smart' soft materials could find many important applications ranging from personalized therapeutics to soft robotics. However, as most molecular materials are unable to communicate, or even respond to, changes in their environment, truly smart materials are still far out of reach. Signal transduction is one of the primary processes used by living cells to react to events taking place in their environment, often involving a signal triggering enzymatic activity, leading to a cellular response. Such rudimentary communication is entirely non-existent in synthetic materials. I here propose the introduction of catalysis-based signal transduction between chemical systems to enable synthetic materials to respond autonomously to events taking place in their environment. Key to achieving this objective will be the development of switchable catalysts, using signals originating from chemical events to change catalytic activity, and coupling changes in catalytic activity to responses in soft materials. In achieving these objectives, I will develop new design strategies for responsive soft materials, enabling control over material formation and response in time and space, through autonomous reaction to chemical signals. This will allow the development of new actuators, self-healing materials, sensors, therapeutics and self-regulation and self-correction of material assembly. It will also constitute an entirely new role for catalysis, as catalysis will be engaged to constitute a first step towards achieving communication between artificial ch
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Democratic Innovations and Citizens in the EU'.

assistant: **Innovation**

Representative democracies are currently challenged by an increasing decline of political satisfaction and trust. Many European governments have tested diverse democratic innovations with the aim of enhancing political contentment as well as increasing citizens’ understanding of political matters. However, do democratic innovations, for example direct democracy or deliberative procedures, fulfil the hopes? This question remains unanswered, because currently no comprehensive data pool, no theoretical framework, and no systematic evaluation of democratic innovations in Europe exist. The applying fellow, Brigitte Geissel, and the applying institution, the Interdisciplinary Centre of Excellence “Democracy: A Citizen Perspective” at Åbo Akademi University (Finland), will address this gap and meet the demand of political scientists and politicians alike for valid expertise regarding the advantages and disadvantages of democratic innovations.  The objectives of the research project are, in short, (1) to pool the theoretical and empirical knowledge on different innovations, (2) to develop a theoretical framework with criteria for the evaluation of democratic innovations, and (3) to explore the advantages and disadvantages of democratic innovations by secondary analysis in comparative perspective. The project will focus on democratic innovations in European states, with an emphasis on the Nordic countries, which are especially advanced in that field.  The objectives of the applicant are to develop further professional, methodological and management skills, to establish international research networks, especially with the Nordic countries, and to open up as well as to establish a new research topic.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Decentralizing Conceptual Art's Internationalism: Latin American artists in Western Europe, 1968-1979' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

My proposed project problematizes Conceptual art’s internationalism and its historicization with an innovative study on transnational artists who expatriated from Latin American repressive political regimes to Europe, establishing themselves in Belgium, England and the Netherlands between 1968-1979. The objective is to assert these artists as agents of transcultural processes and their conceptual practices as operating within a dynamic matrix that is at once local and international, deterritorialized and rooted. Through an analysis of unique data collection, oral history and artworks this research aims to fundamentally revise the art historical canon by de-centering the major narrative of Conceptual art of the 1960s and 70s to comprehensively address the prominent roles these artists had on their adopted localities, a Latin American diasporic art world and the formulation of internationalism. By focusing on the interstitial spatial regimes these artists occupied and created, this research effectively redraws the discipline’s original topography and conventional analyses fixed within national paradigms towards a logic of transnationalism fueled by the mobility of agents, objects and practices. In the example of this project, a transnational methodology reassesses regional art histories — Belgian, Dutch, English and Latin American — to capture interregional flows and networks of production. Furthermore, it underscores a present condition in which geographical and cultural borders are increasingly more connected. The topic is timely in regards to the evolving understanding of Conceptual art. More specifically, the issues of exile, mobility, internationalism and localism that figure into this work offer a unique case study into Conceptual art’s role in driving and defining
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Twinning European and third countries river basins for development of integrated water resources management methods' (TWINBAS).

assistant: **Concept**

Strategic objectives. To fill gaps in knowledge and methods in order to enable implementation of a harm sided IWRM approach that addresses the European Water Initiative, in five river basins. To enable and perform assessment of vulnerability to climate change and anthropogenic development, and produce integrated river basin management plans, that includes optimal combinations of actions. To reach the strategic objectives of TWINBAS, a number of research tasks on hydrology, modelling of pollution flow, impact assessment, socio-economics, scenario analyses and action efficiency have to be carried through. For all these activity areas, the goal is to bring knowledge to a level where IWRM can be implemented for the five twinned river basins; Katanga (Botswana), Nora (Kazakhstan), Bio (Chile) Thames (UK) and Nordstrom (Sweden). TWINBAS will have an important strategic impact by creating the practical means for implementing the EU Water Initiative 'Water for Life'. The nature and width of the gaps in knowledge vary between the different case study rivers, and therefore the research required differs between the river basins. The research and the IWRM components of TWINBAS are organised according to the EU Water Framework Directive (WFD) so that the FWD guideline documents can be utilised. The proposal also addresses the EU Water Initiative, which promotes development that is demand led from the less developed countries. The strong component of public participation and stakeholder involvement will ensure that each component has local ownership and addresses priorities identified within the region. The river basins selected represent a wide variety of water use problems, and a variety of political and societal systems.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Targeting DNA repair pathways, sparking anti cancer immunity'.

assistant: **Objectives**

This project will test for the first time the hypothesis that therapeutic inactivation of DNA repair pathways in cancer cells can be exploited for patient benefit by reawakening an anti-tumor immune response.Genomic instability and molecular heterogeneity, which occur in cancer cells with DNA repair deficiencies, fuel tumour progression and are associated with poor outcome. An exception is represented by Mismatch repair (MMR) deficient cancers as these tumours are exceedingly genetically heterogeneous but show favourable prognosis and remarkable response to immunotherapy.The molecular basis for the clinical outcome of MMR deficient cancers has long remained a mystery. Only recently it has become apparent that their biological properties are associated with increased levels of mutations, which unleash adaptive immunity and trigger immunosurveillance.We have reported that when MMR is impaired, cancers cells grow in immune-deficient mice but are unable to do so in immune competent animals. MMR inactivation increased the mutational burden and led to dynamic mutational profiles, resulting in persistent renewal of neoantigens and engagements of antigen-specific T cells.These data suggest an unprecedented high risk-high gain approach: the pharmacological blockade of proteins involved in DNA-repair as an anticancer therapy. This unconventional strategy builds on the concept that the immune system can identify and selectively target tumor cells carrying DNA alterations.Using in vitro and in vivo functional assays we will systematically assess whether and how inactivation of DNA repair genes provokes an immune response and restrict cancer growth. Notably, TARGET will discover and develop inhibitors of MMR and other DNA repair proteins that induce tumor immunity.The identification
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Characterization of the cytokine network accompanying tumor development and its influence on nitrogen metabolism in the tumor bearing mice' under Fourth Framework.

assistant: **Concept**

The Project is involved in the characterisation of the cytokine network accompanying tumor development, and its influence on the nitrogen metabolism of the tumor-host system. Ehrlich ascites tumor cells will be used as a tumor model growing in the peritoneal cavity of mice and in 'in vitro' cultures. Glutamine and the main enzyme involved in its degradation, glutaminase, will be the target of the studies relating nitrogen metabolism. Cytokine production will be measured using the technique of intracellular staining and further evaluation by FACS and fluorescence microscopy. T cells and antigen presenting cells will be analyse for cytokine production as well as the tumor cells. Monoclonals antibodies against tumor glutaminase are pretended to be obtained and used to stain glutaminase intracellularly and correlate its expression with cytokine production. IL-1, IL-2, IL-4, IL-6, IFN-g and TNF-beta will be the main cytokines involved in the study.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Curved Applications for Rotorcraft Environmental enhancement'.

assistant: **Objectives**

The CARE project – Curved Applications for Rotorcraft Environmental enhancement – will support the definition of new rotorcraft IFR curved operations benefiting from SBAS guidance. In this project, on top of the innovative character of those procedures, the consortium will really CARE about minimizing noise impact. Concrete milestones will be implemented to address various types of operational and regulatory issues that rotorcraft operators will have to tackle. The CARE project will bring state-of-the-art expertise in Air Traffic Management to meet the CleanSky JU objectives. A major Air Navigation Service Provider supported by the National Regulator, two specialized engineering companies and, procedure designers, have teamed up to ensure:•The definition of tailored criteria for designing low noise optimised curved procedures for rotorcraft,•The safety assessment of the new procedures,•The identification of the benefits brought by those specific curved applications,•The promotion of these new types of operations through the implementation of a concrete procedure,•The appropriate dissemination of CARE results encompassing the organization of a dedicated user forum with the different Stakeholders.Involved in GNSS projects and Air Traffic Management for many years, the Egis Avia Company will lead the consortium to help making the required breakthrough a reality.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'GO4IT! - Grasping opportunities for Internet and electronic commerce technologies development' (1998-2002), addressing dissemination and exploitation.

assistant: **Impact**

The objective of GO4IT! is to support European SMEs in implementing their business and innovation plans that involve a closer approach to Internet and electronic commerce technologies. Partners and NCPs from Italy France, The Netherlands, Portugal and Norway are involved in the action and will support SMEs in the participation to IST Programme, Key Action 2 and 4, through awareness actions, technology audits, market and technology trends analysis, proposals definition assistance and partner search. GO4IT! results will be disseminated through multipliers that replicate the experience and outcomes of GO4IT!. A selection of IST RTD results in the area of Electronic Commerce and Essential Technologies will be made on the basis of the identified SMEs technology needs and will be proposed as technological solutions to be further exploited within new IST projects.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Nanowire based Tandem Solar Cells' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Silicon based photovoltaic cells are the dominant technology for terrestrial solar energy conversion. After many decades of research and development, efficiencies are today flat with the best devices measuring 25 % in the laboratory. Significantly higher conversion efficiencies up to 38.8 % are so far only reached with multi-junction cells based on III-V semiconductors. However, these materials are too expensive for the use in flat-plat modules. Nanowires allow to significantly reduce material needs without compromising absorption or performance. The consortium has already shown InP single-junction nanowire solar cells on InP substrate, reaching world-record efficiencies of 13.8 % and using only 12 % of the volume of a conventional bulk solar cell. Combining III-V nanowires with today’s silicon photovoltaic technology offers the potential to reach at the same time very high performance devices, efficient use of materials and low cost. In this project we are aiming to demonstrate time an experimental proof of a tandem solar cell composed of a top pn-junction formed in III V nanowires and series connected to a bottom pn-junction formed in silicon.Such solar cell devices are either fabricated by direct growth of the nanowires on Si or by transferring a film of nanowires embedded in a polymer onto a Si bottom cell. Besides developing the best process to demonstrate such tandem solar cells with > 25 % efficiency, we are also addressing the important aspect of scaling up the technology to large areas. To reach this objective, we are developing technologies for large area III V nanowire arrays (> 10 cm²) based on nano-imprint technology and epitaxial growth or on a new vapour phase growth method of nanowire aerotaxy. The wide-spread application of nano-materials and III-V comp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'BIOsens – cutting-edge portable device for precise and rapid analysis of crops' in the context of a Horizon 2020 call.

assistant: **Objectives**

Every year, companies involved in agriculture businesses experience significant financial losses because of mycotoxins – invisible and dangerous for human health foodborne toxins, which contaminates 25% of the global supply. Farmers, grain elevator owners, and food processing companies suffer the most from this issue and crave for the solution that will allow them easily, swiftly and accurately detect mycotoxins on-site. Timely detection of mycotoxins will prevent them from unsuccessful trade or border rejections, and will lead to revenue increase.BIOsens provides cutting-edge solution that successfully tackles the problem of agriculture companies by creating an easy-to-use portable device for mycotoxin analysis. The mycotoxins testing market is expected to grow to USD 1.75 billion in 2023, and BIOsens is the first solution on the market which combines the accuracy of laboratory testing and the speed of onsite devices.BIOsens team comprises of experts in Biochemistry, Biotechnology, IT and Business which ensure the high quality of the developed solution and successful market entry. According to Financial Times, company’s CEO Andrii Karpiuk is one of 100 eastern Europe’s emerging technology stars and the team has already won numerous start-up competitions, including Intercontinental Startup Battle in San-Francisco.BIOsens aims for global commercialization to ensure that people all over the world consume safe food. SME Instrument Phase 1 funding will enable the company to validate customer needs, conduct thorough analysis of target markets and validate priority countries for market entry, research regulatory requirement and develop an IRP strategy, validate business model and as a result create an elaborated business plan for the successful commercialization of the device
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The Asian Origins of Global Capitalism: European Factories in the Indian Ocean, 1500-1800' (CAPASIA).

assistant: **Concept**

In the present age of de-industrialisation of the West, the origins and evolution of global capitalism matters. CAPASIA locates the origins of modern industrial capitalism in the space of Asian ports in the Indian Ocean, where the Portuguese, as well as the Dutch, English, French, and other European East India companies operated in the early modern period (1500-1800). Well before the rise of 20th-century Special Economic Zones and world financial centres, the ports of maritime Asia (‘factories’) were areas of global trade and hubs of economic dynamism. Today ‘factories’ are places of industrial production, but they owe their name to these pre-modern Asian trading ports, European-controlled trade hubs headed by company servants called ‘factors’. Factories were places where commodities for intercontinental trade were assembled, stored and shipped.  This project investigates the genesis, evolution, activities, and connections of over 150 small and large such factories as the foundation for a new spatial theory of capitalist development — complementing and challenging the current Atlantic plantation-based explanations proposed by the New History of Capitalism. CAPASIA’s integration of the large archival repositories of the different European East India companies and Asian archives will also be the basis for the ‘decolonization’ of the history of capitalism. Over its five-year duration, this project will ask: what kind of economic activities were carried out in these imperial trading centres? What were the interactive roles of European and local merchants? It will map the intercontinental movement of goods, people and information across an ‘archipelago’ of Asian ports. Working with collaborators from across the globe, CAPASIA’s overarching ambition is to recast the narrative