RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Campus projekt dortmund' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

The action aims to install a focal point for the development of managerial and enterprise talent and would create an establishment uniquely adapted to the exploitation of ideas, theories and manufacturing technology to contribute to Europe's pursuit of industrial efficiency and effectiveness in the face of global competition. IT which underlies so much of business and manufacturing efficiency would have found a vehicle for the rapid dissemination and exploitation of research results within a very dynamic environment. A further step towards the development of the Information Society would have been taken by instituting a facility where research and experimentation into the application of all facets of IT can be performed, whilst the skills needed by the working public can be examined and improved through the provision of short, practical training.The action will bring about an installation where small and medium sized enterprises would operate in great physical proximity to first class academic and professional resources with access to the latest developments in product and process technology. The interaction of the resources is expected to provide high levels of synergy both in problem solving for immediate applications and training 'seeding' experts who would be able to carry know-how into other areas.By integrating into one location production capacity, research laboratories, management faculties and retraining facilities with access to the latest technologies, it is planned to confront problems of industrial competitivity and hence unemployment through deriving and implementing strategies for life long learning in an appropriate environment. This approach may lead to a model which could be applied elsewhere in Europe.CAMPUS, the Centre for Advanced Management, Projec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Integrating Rural Migrants in Cities - A Field Experiment in Mozambique'.

assistant: **Objectives**

Sub-Saharan Africa is the world’s fastest-urbanizing region. The movement of people from the countryside to denser cities will likely create progress toward some of the Sustainable Development Goals in the medium term, especially SDGs 11 (Sustainable Cities and Communities), 13 (Climate Action), 8 (Decent Work and Economic Growth) and 5 (Gender Equality). However, rural-urban migration can also cause disruption and conflict in the short term. Furthermore, many autocratic national governments oppose urbanization because it increases the cost and difficulty of controlling citizens through patronage and intimidation. Therefore, the responsibility often falls on city-level governments in the developing world to peacefully integrate new migrants with existing residents, and there is an urgent need for evidence on how to do so. This project will help meet this need in the context of the Mozambican city of Quelimane (pop. 350,000). Quelimane has created a program for rural migrant integration that includes job matching, training and education, financial services, and tax incentives. The government of Quelimane has invited me and my supervisor at NovaSBE, Pedro Vicente, to conduct a randomized controlled trial (RCT) to rigorously measure the causal impact the program, by selecting randomly which blocks in the city will be eligible for the program first. To measure both the direct effect of the program and its externalities, we will survey 500 long-term residents in treatment and control blocks as well as 1000 recent migrants and their still-rural connections. We plan to study not just how the program affects livelihoods, but attitudes, prejudices, political attribution, and further migration. Understanding how Quelimane can improve the urban integration of rural – and which par
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'CIRCULATING TUMOR DNA AS AN EPIGENETIC BIOMARKER FOR TUMOR RESPONSE' (INITIATOR) under Horizon 2020.

assistant: **Objectives**

Tumors are characterized by a disorganized vasculature, leading to profound levels of hypoxia. Normalizing the blood vessel formation (angiogenesis) in tumors has therefore become an attractive therapeutic strategy, leading to the development of approved drugs that inhibit major angiogenic pathways. Resistance however restricts the success of these anti-angiogenic drugs in some patients. There is thus a great clinical need for readily accessible markers that serve as reliably predictive biomarkers of anti-angiogenic therapies. However, all markers discovered to date have a limited predictive power. In the ERC Consolidator Grant CHAMELEON, we discovered how tumor hypoxia causes DNA hypermethylation and how changes in DNA methylation underlie resistance to anti-angiogenesis. Here, we propose to validate how methylation patterns detectable in plasma circulating free DNA from a prospective collection of patients with metastatic colorectal cancer can be used to predict an early response to anti-angiogenic therapies by using our in-house developed cfDNA co-methylation test, referred as the ‘INITIATOR’ test. If successful, we anticipate that this project will overcome many of the issues that are currently associated with anti-angiogenic drugs: cfDNA is readily accessible and can be serially sampled during treatment or follow-up, cfDNA also mirrors the entire tumor and not just the biopsied site, while the epigenetic changes detectable in cfDNA may be a dynamic representation of the tumor in response to treatment.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Entangled Interfaith Identities and Relations from the Mediterranean to the United States: The St James Association and Its Transnational Christian-Jewish Network in the Israeli-Palestinian Conflict' in the context of a Horizon 2020 call.

assistant: **Objectives**

Mixed religious identities and interfaith relations represent one of the most crucial and debated phenomena in the 21st century. The revival of the religious dimension in the world is evident in the growing religious implications in modern and contemporary wars. The REL-NET project tackles these global issues through the analysis of a significant case study that has been overlooked in the historiography: the history of Christian–Jewish transnational networks between Israel, Palestine, the Middle East, Europe and the United States after the establishment of the State of Israel in 1948. In particular, I will focus on the history of the St James Association (SJA) since the end of the 1940s. The SJA is a community formed by Holocaust survivors who converted to Christianity, moved to Israel and settled in the mainly Arab Jerusalem Church. Some SJA members became well-known intellectuals who developed an international network that influenced Christian–Jewish–Muslim relations during the Israeli–Palestinian conflict and on a global scale. Using multiple and interdisciplinary methodologies and an unprecedented mass of unpublished archival documentation disseminated all over the world will lead me to retrace the strands that contributed to the new relations between Jews and Christians while also engaging Muslim communities. Involving an extensive programme of teaching, language, digital and project management training at Fordham and Ca’ Foscari universities and under the supervision of two leading scholars in these fields, the MSCA-GF will give me the extraordinary opportunity to outline a new framework for the historical appraisal of religious relationships in the contemporary world, delivering innovative outputs in terms of academic products and in disseminating them to a large
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Neutron data measurements at IRMM' (NUDAME), addressing dissemination and exploitation.

assistant: **Impact**

The Joint Research Centre has as one of its key objectives in FP6, the full opening of its infrastructure to European scientists and industry. The Reference Laboratory for Neutron Measurements of the IRMM (Geel, Belgium) is equipped with a unique scientific infrastructure of European relevance. Therefore it is ideally suited to fulfil this objective. The research infrastructure is centred around two accelerator facilities: GELINA is a 150 MeV electron accelerator serving as strong white neutron source for high-resolution neutron time-of-flight measurements.The facility covers the energy range from thermal to 15 MeV, has unsurpassed time resolution of less than 1 ns FWHM and serves an array of flight paths up to 400 m long on which as many as 12experiments can be carried out simultaneously. The 7 MV van de Graaff facility is an electrostatic accelerator for the production of continuous and pulsed proton-,deuteron- and helium ion beams. Six beam lines and experimental set-ups are attached to the accelerator. Quasimono-energetic neutrons in the energy region 0-24 MeV are produced by using lithium, deuterium or tritium targets. Both facilities are typically operated on a 3000 to 4000 hours per year basis. We have already a longstanding tradition of international collaborations with access to our facilities for researchers from the EU, the Associated States and abroad.Within the framework of the Euratom Transnational Access programme, we have the intention to increase the available beam time offered to outside users. Any type of experiment in the areas of radioactive waste management, radiation protection and other activities in the field of nuclear technologies and safety can be proposed provided our experimental infrastructure can offer a significant added value to the pro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Polymer Biotechnological Metallization' in the context of a Horizon 2020 call.

assistant: **Objectives**

Injection moulding industry in Europe is in recession and there is a clear need to take actions in order to allow the recovery of this industry. Surface treatment of injected products offers the opportunity to add value to products and to enter in new industries. The automotive market is the most valuable injection moulding sector where surface treated (metallized) objects are used for functional parts (headlights) and aesthetic parts (decorative finishing). The current technology for the metallization process is usually vacuum deposition. The limitations of vacuum deposition are well known, where high investment in the technology, negative environmental impact and high-energy demands are the most prominent.  A biotechnological solution for polymers metallization is a novel solution, where algae are used to deposit metals on selected surfaces. There are no similar solutions worldwide and the implementation of this technology will address several EU directives and guidelines with benefits in the industry and environmental protection. POLYBIOMETAL project will allow the commercialization of a disruptive green technology that will allow cost efficient, fast, simple and environmentally friendly metallization of polymers. POLYBIOMETAL is a novel and disruptive technology that uses algae for the metallization of polymers. This process will allow a sustainable and more competitive metallization process.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Vertebrate isotopes and the environment' (VISE), addressing dissemination and exploitation.

assistant: **Impact**

Predictions of the impact of future climate change have to be grounded in a firm understanding of environmental change in the geological past. Proxies for the isotopic composition of past oceans are widely used to give an insight into their water chemistry and, by extension, the surface temperature of these oceans. Variations in the ratio of Oxygen 16:Oxygen 18 (δ18O) are the most widely utilized proxy for water temperature, and are typically derived from fossil hard tissues, with the δ18O of biogenic apatites such as that of fish teeth being considered to be the most robust. Nevertheless, the isotopic behaviour of fossil biogenic apatites in general, including the effects of diagenesis and other postmortem artefacts, is still not fully understood, which ultimately reflects a lack of primary and systematic study. This project tests the reliability of biogenic apatite δ18O in a controlled modern environment, utilizing the regularly shed teeth of sharks living in a contained body of water from which we can directly monitor variations in isotopic composition and also assess compositional variation due to species fractionation. This will also provide the basis for rigorous testing of the proposition that the isotopic geochemistry of marine vertebrate biogenic apatites are influenced by standard laboratory processing methods of fossil materials. Using evidence derived from these experimental studies, taxonomic variations in isotopic composition within phylogenetically distinct fossil vertebrates through documented intervals of palaeoclimatic change in the Palaeozoic will be evaluated. The results of this project will provide a critical and timely test of the use and limitations of vertebrate biogenic apatite proxies in the reconstruction of past climates. Our project will pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Proteomics v3.0: Development, Implementation and Dissemination of a Third Generation Proteomics Technology' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Quantitative proteomics is a key technology for the life sciences in general and for systems biology in particular. So far, however, technical limitations have made it impossible to analyze the complete proteome of any species.  It is the general goal of this proposal to develop, implement, apply and disseminate a new proteomic strategy that has the potential to generate quantitative proteomic datasets at an unprecedented depth, throughput, accuracy and robustness. Specifically, the new technology will identify and quantify every protein in a proteome. The title of the project Proteomics v3.0 was chosen to indicate the transformation of proteomics into its third phase, after 2D gel electrophoresis and LC-MS/MS based shotgun proteomics. Proteomics v3.0 is based on two sequential steps, emulating the strategy that has been immensely successful in the genomic sciences. In the first step the proteomic space is completely mapped out to generate a proteomic resource that is akin to the genomic sequence database. In the second step rapid and accurate assays will be developed to unambiguously identify and quantify any protein of the respective proteome in a multitude of samples. These assays will be made publicly accessible to support quantitative proteomic studies in the respective species.  The strategy will first be implemented and tested in the yeast S. cerevisiae. In a later stage of the project it will be extended to the more complicated human proteome and include the development of assays that also probe the state of modification, splice forms and other types of protein variants generated by a specific open reading frame. Overall, the project will transform quantitative proteomics from a highly specialized technology practiced at a high level in a few laboratories worldw
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Lupinus mutabilis for Increased Biomass from marginal lands and value for BIOrefineries' (LIBBIO).

assistant: **Innovation**

The Andes Lupin (Lupinus mutabilis, tarwi) grows excellently in marginal lands due to it´s excellent foraging characteristics having the ability to fix nitrogen, mobilise soil phosphate and have low nutritional requirements for cultivation. For the increased biomass needed in Europe in coming years and decades we cannot rely on the most fertile lands, which is currently allocated to food production, we need to increase the yield from marginal lands. There the lupin varieties are preponderant, the one providing highest yield (up to 80 ton/ha) is Lupinus mutabilis. Varieties can be chosen for giving this high yield of green silage or high yield of seeds contain more than 20% oil, more than 40% protein and the remainder carbohydrates are mainly oligosaccharides characterized as “prebiotics”. Andes lupin can be grown as a summer crop in N-central Europe conditions and as winter crop in Mediterranean conditions.  Breeding and cropping research is performed in the LIBBIO project for maximizing the yield and value of lupin agriculture in different European marginal lands conditions, with respect to both the farmers and biorefineries. Pre-industrial processing is developed and optimized for the lupin, properties of the different fractions analysed, their advantage for different industrial use evaluated, and a few products developed as an example. With respect to environmental impact the lupin is expected to be superior. It does not need much fertilizer, it enriches the soil with nitrogen and phosphate and is therefore expected to be excellent for crop rotation and soil regeneration. These properties will be evaluated further in the project along with techno-economic and agricultural viability and effect on farm and biorefinery income.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The evolutionary consequences of inbreeding in natural populations: Genotypic-phenotypic interactions and implications for genetic diversity and evolutionary potential' under Seventh Framework.

assistant: **Concept**

Studies of processes that maintain genetic variation for fitness are fundamental for understanding evolutionary forces shaping the life histories and phenotypic characteristics of animals. Such processes include evolutionary interactions between population genetic structure and mating system, dispersal patterns and social organization. The interplay between genetic diversity and adaptive evolution ultimately provides the necessary understanding for predicting evolutionary response to environmental change. My research proposal seeks to understand the selective forces underlying the evolution of cooperation and the evolutionary consequences of evolving inbreeding mating systems by merging ecological, genetic and genomic methodologies in a highly integrative and interdisciplinary approach.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Evolution of the Cochlea and Hearing in Odontocetes', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Toothed whales (Odontoceti) are a spectacular example of evolutionary adaptation, highly specialised apex predators and a key component of modern ocean ecosystems. The key innovation that has facilitated their evolutionary success is echolocation. Research into odontocete hearing has so far been biased towards physiological experiments and auditory pathway identification; quantitative studies on the cochlea are lacking, despite its critical role in audition. I will fill this gap in knowledge of the cochlea in cetaceans by: (1) quantifying differences in the morphology of odontocete cochlea through the application of cutting-edge scanning, visualisation and quantitative analytical techniques (e.g. 3D geometric morphometrics) to gather in depth data of all features of a fully representative  range of odontocete cochlea; (2) testing through statistical analysis whether these differences correlate with, or are driven by, factors such as diet, behaviour or auditory sensitivity; (3) incorporating fossil taxa to pinpoint the timing of the evolution of echolocation; and (4) identifying convergent evolution of specialised high frequency hearing in river dolphins using novel methods for testing and quantifying morphological convergence. This project will create the most comprehensive data set of odontocete inner ear models ever compiled and will mark a major advance in the understanding of cetacean sensory evolution, providing profound insights into how this enigmatic group of marine mammals came to dominate the oceans - making sense of a sixth sense. The data gathered will be made openly available to other researchers.