RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Engineering macromolecular self-assembly of hyaluronan (HA)-based glycopolymers with peptides' (HA).

assistant: **Innovation**

Sugars and amino acids are natural building blocks which are used to form precisely regulated sequences in carbohydrates and proteins, respectively. While the field of proteomics has advanced immensely during the last past years, the field of glycomics is much less developed. The advance in synthetic polymer chemistry is allowing the possibility of controlling monomer sequences in synthetic macromolecules with diverse chemical structure providing many scientific and technological applications. “SuprHApolymers” project aims to design and synthesize glycopolymers mimicking the composition and structure of hyaluronan (HA), a linear polysaccharide composed of repeating disaccharide units of N-acetyl-glucosamine (GlcNAc) and glucuronic acid (GlcUA), but with many important biological functions. Linear glycopolymers, made solely of GlcNAc or GlcUA sugars (homopolymers) or containing both sugars (copolymers) will be synthesized to study their interaction with synthetic peptides bearing HA-binding motifs (peptide library). The synthesis of HA-based glycopopymers with branched architecture will be also attempted to explore different polymer configurations and to create optimal interactions with peptides. The self-assembly of HA glycopolymers with peptide amphiphiles containing selected HA-binding sequences will be investigated to form de novo peptide-polymer hybrid supramolecular materials with different molecular and macroscopic properties. Finally, the formed functional assemblies (nanostructures and supramolecular gels or films) will be explored for applications in synthetic biology and biomedicine.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Energy savings from smart operation of electrical, process and mechanical equipment' (ENERGY-SMARTOPS) under Seventh Framework.

assistant: **Objectives**

The drive across the world towards energy efficiency and reduction of CO2 emissions is leading to new industrial processes and new ways of operating existing processes. In particular, the control and operation of processes, rotating machinery and electrical equipment is becoming radically more integrated giving new opportunities for energy saving through equipment management, automation, and optimization.In the light of these challenges, there is a need for new training and research action to address technology gaps at the interfaces between the process, mechanical and electrical domains, and to realize energy savings from integrated operation. The ENERGY-SMARTOPS consortium has detailed plans for cross-disciplinary training of a cohort of Early Stage engineering researchers through personalized programmes which will provide experience of research as an exciting and rewarding career, in-depth training in research projects at the host site and on intersectorial secondments, local and network-wide courses on technical topics, complementary skills training, and participation in workshops and symposia.The research programme is organized into three themes: (i) Equipment and process monitoring integrating multiple measurements from the process, mechanical and electrical sub-systems, (ii) Integrated automation capturing information from all three subsystems, and devising new algorithms that explicitly manage the interfaces and interactions between them, (iii) Optimization to provide energy savings by better integration of operations across the process-mechanical-electrical interfaces.The consortium involves universities and the R and D groups of end-user companies and an industrial technology supplier. Its investigators are experts in electrical machinery and power electronics
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for '3DTV Content Search' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

As 3DTV emerges, 3DTV content started already being accumulated in 3DTV broadcasters and 3D video production houses. Its volume will soon rise tremendously. Such content already started being posted in the web, as already done for 2D audiovisual material. Furthermore, with the advent of 3D mobile devices, such content is expected to be posted soon in social networks or user-fed audiovisual archives (e.g. YouTube). Such 3DTV audiovisual content consists primarily of stereo, video+depth or multiple views video and multichannel 5.1 or 7.1 sound and must be properly archived, searched and retrieved.  However, it cannot be accommodated well within classical audiovisual media archives, because such archives do not exploit depth information, when indexing, searching, retrieving and browsing 3DTV content. Certain tasks, e.g. creation of 3D video summaries and browsing are inherently different in 3D than in 2D content. Therefore, new efficient schemes must be devised for content-based 3DTV audiovisual (AV) content description, indexing, fast search and browsing.The goal of the 3DTVS project is to devise scalable 3DTV AV content description, indexing, search and browsing methods across open platforms, by using mobile and desktop user interfaces and to incorporate such functionalities in 3D audiovisual content archives. The major novelty in 3DTV content indexing/retrieval research will be on how to exploit 3D (depth) information for stereo and multiview video indexing, retrieval and browsing that could address semantic queries of the form 'find stereo videos with shallow depth' or 'find stereo videos, where actor X approaches actor Y'. 3D multichannel audio analysis will perform better audio source (e.g. musical instrument) separation and localization that will be used in 3D audio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Modelling of induction machines for monitoring and diagnostics' under Fourth Framework.

assistant: **Concept**

Research objectives and content The aim of this project is to develop an induction motor model suitable for the simulation of the relevant physical phenomena which may affect the stator current spectrum. To develop this model, the circuit- oriented approach has been chosen in order to modellize the induction motor as a rotating transformer. In this way, the aspects which may be considered suitable for exact modelling are related to the magnetic core, insulating material and winding geometry. Then, electromagnetic theory must be applied to define the most important physical phenomena to be studied. The final model must be tested simulating failures experimentally achieved as winding short-circuits or cut- sets and transient voltage externally produced for the stator, and broken bars or rings, the most common failures for the rotor. Comparison of theoretical and experimental results will indicate the application domain of the model. Then, techniques and methods for monitoring and the diagnosis of induction motor operation may be treated with this model, limiting destructive experimental tests commonly used in this research area. The induction motor model will be developed with the circuit-oriented package EMTP (ElectroMagnetic Transients Program) and a particular simulation methodology proper for this study will be applied. Training content (objective, benefit and expected impact) This project proposes to develop a modelling technique applied to induction motor failure studies. In diagnostics methods using simulation tools, the main faults can be assessed using spectral or time-domain analysis. With this technique, maintenance and operation conditions of electrical equipment can be better observed leading to cost-less operation in industry. Links with industry / industria
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'The impact of HCV diversity on replication fitness and protease inhibitor sensitivity in HIV infected patients with chronic HCV' in the context of a Seventh Framework call.

assistant: **Objectives**

Hepatitis C virus (HCV) is a major cause of premature death due to cirrhosis and hepatocellular carcinoma in a large proportion of the world population (>25 million). Recently, advances in the development of new therapeutic compounds to treat HCV have revealed several potent inhibitors of the HCV serine protease, which have reached clinical trials. However HCV has a high genetic variability, not only between genotypes but also between quasispecies of an infected individual. In HIV coinfected patients the levels of complexity and diversity of the HCV protease gene variants and the resultant impact on HIV coinfection are unknown. The advent of HCV genotype 1b derived replicon systems has enabled measurement of HCV subgenomic RNA replication in a cell-based format and aided the development in the new therapeutic compounds. However these replicons are not representative of the genetic variability within the HCV genotypes, subtypes and quasispecies. In this project proposal we wish to clone HCV NS3 sequences derived from the sera of HIV infected patients with chronic HCV to address the impact of diversity on replication fitness and the drug sensitivity in a transient replication assay. The importance of HIV co-infection will also be investigated. The project will take place in the Center for the Study of Hepatitis C, New York, USA were the state of the art techniques are currently being used. In the returning phase the methodology and experience will be transferred to Europe at the Hospital Carlos III, Madrid, Spain an institute renown for its research in HIV and viral hepatitis co-infection. This project will help understanding the mechanism of HCV drug resistance and will provide relevant information for the design of new anti-HCV drugs
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Spatially-Separated Chirality Inspired Networks' (SCHINES) under Horizon 2020.

assistant: **Objectives**

Creating a brain-inspired technology through neuromorphic engineering could achieve or even surpass the extraordinary ability of the brain to grasp the world, which operates at an extremely low power consumption yet with the most complex interconnectivity known to mankind. The main goal of SCHINES is to set a clear direction to solve one of the biggest technological challenges that hinders this revolution: in existing physical neural network architectures, the desired interconnectivity can hardly be achieved. We will fabricate and design devices to demonstrate radically improved signal routing using topological metals. The design principle is simple: the environment of chiral electrons, electrons with spin locked to its momentum, can be engineered to create rich electronic lensing effect, analogous yet broader to light in-media propagation. Positive and negative effective indices of refraction for electrons, and lossless signal crossing can be engineered while maintaining, selecting or filtering the intrinsic topological protection of chirality, a degree of freedom that can be used for computation. These design principles are the basis for our device goal with scalable interconnectivity and are highly transferrable: they apply to strained materials, magnetic domains and heterostructures. This ambitious goal is realistic due to the interdisciplinary breadth of the SCHINES consortium: it is built out of established and emerging leaders called to shape the future of the field, joined in a public-private collaboration. They comprise an expertise that bridges the gap between the most abstract quantum field theory calculations with microscopic modelling with sample fabrication and measurement finalizing in device assembly


**Keywords:** Electrical engineering, Physics, charg
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Access to research spectroscopic data and associated chemical knowledge (EUROSPEC)' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

The EUROSPEC project will establish the infrastructure necessary to generate high quality reference spectroscopic databases from the scientific literature with links to available associated chemical knowledge. The network will coordinate electronic data submission from peer-reviewed journals and make the data available to the reviewers and finally the scientific community. The consortium consists of experts in the difficult field of spectroscopic data handling and metrology with previous experience in solving similar problems at EU and international level. The consortium also includes international experts in the development of new spectroscopic data standards and the presentation of scientific data in a web based environment.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Exploring and Preventing Cryptographic Hardware Backdoors: Protecting the Internet of Things against Next-Generation Attacks' (EPoCH).

assistant: **Concept**

The digital landscape is currently undergoing an evolution towards the Internet of Things. The IoT comes with a dramatically increased threat potential, as attacks can endanger human life and can lead to a massive loss of privacy of (European) citizens. A particular dangerous class of attacks manipulates the cryptographic algorithms in the underlying hardware. Backdoors in the cryptography of IoT devices can lead to system-wide loss of security.  This proposal has the ambitious goal to comprehensively understand and counter low-level backdoor attacks. The required research consists of two major modules:1) The development of an encompassing understanding of how hardware manipulations of cryptographic functions can actually be performed, and what the consequences are for the system security.  Exploring attacks is fundamental for designing strong countermeasures, analogous to the role of cryptanalysis in cryptology.2) The development of hardware countermeasures that provide systematic protection against malicious manipulations. In contrast to detection-based methods which dominate the literature, our approach will be pro-active. We will develop solutions for instances of important problems, including hardware reverse engineering and hardware hiding. Little is known about the limits of and optimum approaches to both problems in specific settings.Beyond prevention of hardware Trojans, the research will have applications in IP protection and will spark research in the theory of computer science community.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Differentiation between migratory and sedentary bird populations' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

This project will investigate the mechanisms underlying the persistence of morphologically different migratory and sedentary populations of birds despite the winter in sympatry. paying special attention to gene flow and the consequences of co specific interactions in wintering grounds.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Healing Encounters: Reinventing an indigenous medicine in the clinic and beyond' under Horizon 2020.

assistant: **Concept**

What is the difference between healing and curing? What understandings of wellness, illness and bodies underpin different healing practices? How is therapeutic efficacy assessed in a context of competing valuation practices? This project aims to develop a symmetrical, ethnographically grounded theory of what healing entails from the perspective of those who give, receive or evaluate healing. It is designed to break with binary frames that contrast indigenous and biomedical healing, positioning them on a tradition–modernity continuum. To do this, it will study the striking expansion and prolific reinventions of healing practices that make use of the Amazonian herbal brew ayahuasca. The unprecedented globalization of this indigenous medicine provides a unique opportunity to study healing encounters ethnographically.Through participant observation, interviews, ethnography in expert settings, collaborative workshops and the use of digital methods we will study healing across three related sites: Healing in the City will examine the production of neotraditional urban healing forms. Healing in the Laboratory will analyse how ayahuasca is reinvented as a psychiatric tool to treat mental health problems and Healing in the Forest will study the contemporary reconfigurations of indigenous shamanism. These practices are entangled in long histories of postcolonial encounters: they are all – neotraditional, biomedical and indigenous alike – thoroughly modern and mixed. The comparative analysis is structured around three transversal objectives: 1) Material Semiotics: To develop an innovative framework to map the entanglement of biological and symbolic effects. 2) Encounters Beyond-the-Human: To push medical anthropology beyond the human by paying attention to the healing propitiated
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Novel approaches to induce mucosal immunity against tb using the combined adjuvant strategy of cta1-dd and iscoms (ISCOTB)' (ISCOTB).

assistant: **Concept**

This is the continuation of a highly successful EU project that has contributed greatly to our knowledge of how to construct novel adjuvant systems. We achieved proof of principle, showing that a mussel vaccine adjuvant, with greatly augmented potency, can be designed by combining the enzymatic ally active cholera toxin derived CTA1-DD immunoenhancer with immune stimulating complexes, ISCOMS. This technology is now patented and we propose to explore its potential as a mucosal TB vaccine. To this end, we have added a well renowned ISCOMS patenting and producing company and a research group with a strong track record on research on Mycobacterium infections and vaccine construction. For reasons of safety, efficacy and cost, mussel administration of a vaccine is a priority for immunizing against mussel and systemic infections. Recent progress has identified the mussel route as superior to other of TB vaccine administration.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Cell-cell interactions at the neurovascular interface' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The coordinated orchestration of cell movements is a vital process for assembling functional structures. In recent years we have learned a simplifying lesson: organ development is governed by a limited set of conserved cell-to-cell communication signaling pathways repeatedly used in different contexts. Particularly fascinating is the parallelism between the vascular and nervous systems. My lab has been working for more than a decade on the molecular and functional parallelism between nervous and vascular system development and plasticity. Although it is clear that cellular communication between the different cells in the brain is fundamental for brain function, very little is known about the signaling effectors that are used for such trans-cellular signaling. Molecular pathways involved in the crosstalk between vessels and neuronal cells are slowly emerging. How this crosstalk signaling is integrated at the interface of the different cellular players (neurons, endothelial cells, glial cells) for proper brain development and function is still poorly understood. Here I propose to delineate the molecular pathways that govern such communication in order to understand basic mechanisms of brain development, function and dysfunction. Using a combination of state-of-the-art inducible and cell type-specific genetics, both in mouse and zebrafish, together with high-resolution light microscopy and multi-photon live imaging we will examine the cell-context dependent integration of signaling pathways in building up proper neuronal/glial structures and functional networks. We will use advanced ultra-structural analysis using serial block-face electron microscopy (SBEM) to obtain high-resolution maps of cortical structures. Functionally, we will characterize the integration of vascula