RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Classification of Forest Structural Types with LiDAR Remote Sensing Applied to Study Tree Size-Density Scaling Theories' under Horizon 2020.

assistant: **Concept**

The main goal of this research is to develop an objective methodology for monitoring forest structural complexity by airborne laser scanning (ALS) remote sensing. Most European countries are currently acquiring low-density national ALS data, by scanning with LiDAR sensors onboard airborne platforms, in the process to obtain full-country coverage and making it publicly available. These datasets are taken in relatively homogeneous conditions, therefore providing with a chance to develop Pan-European indicators and automated unsupervised methods not requiring field data. With the intention of producing a methodology that could be replicated in practice by any forest practitioner, publicly available ALS data from national land surveys of Member States will be used, and unsupervised methods not requiring field data will be developed. The laser partly penetrates the forest canopy, therefore providing an opportunity to study the establishment of natural regeneration in the understory layers. The analysis will be based on the study of the Lorenz curve, a method for which the applicant has obtained promising preliminary results and which the present proposal plans to generalize for more forest ecosystem types and low-density National laser datasets. The diameter distributions will be evaluated with regard to their agreement to metabolic ecology and demographic equilibrium theories. The development of a mathematical framework linking Lorenz ordering to diameter-density scaling relationships will provide with a method for authomated ecological evaluation of forests by means of ALS remote sensing. In practice this means that competition and forest disturbance conditions are different at different forest areas, and we suggest that the Lorenz method for ALS can provide indicators for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Research infrastructure to promote primate molecular biology' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

In the postgenomic era, a better functional understanding of the human genome will only be achieved by comparing our genes to those of other species. Animal models (e.g. mouse) are too evolutionarily distinct to understand many gene functions that characterise humans. The dearth of primate resources for molecular analyses is especially worrying in Europe. We propose to establish a consortium of leading teams to provide the European scientific community with the resources needed to boost primate molecular biology. The resources include non-human primate collections, STRs markers, cell lines, BAC libraries and microarrays and have been selected for biomedical and conservation purposes and to cover the whole range of primate infraorders. The project has broad scientific, political and social implications, such as promoting the role of zoos and museums in education and conservation, and placing Europe in a leading position in this promising field.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Connecting Science with Society'.

assistant: **Objectives**

The rapid changes occurring in the Polar Regions are significantly influencing global climate with consequences for global society. European polar research has contributed critical knowledge to identifying the processes behind these rapid changes but, in contrast to lower latitudes, datasets from the Polar Regions are still insufficient to fully understand and more effectively predict the effects of change on our climate and society. This situation can only be improved by a more holistic integrated scientific approach, a higher degree of coordination of polar research and closer cooperation with all relevant actors on an international level as requested in the Horizon 2020 work programme. The objectives of EU-PolarNet are to establish an ongoing dialogue between policymakers, business and industry leaders, local communities and scientists to increase mutual understanding and identify new ways of working that will deliver economic and societal benefits. The results of this dialogue will be brought together in a plan for an Integrated European Research Programme that will be co-designed with all relevant stakeholders and coordinated with the activities of many other polar research nations beyond Europe, including Canada and the United States, with which consortium partners already have productive links.This consortium brings together well-established, world-class, multi-disciplinary research institutions whose science programmes are internationally recognised for excellence. Alongside these scientific capabilities, the national programmes represented in this proposal possess a unique array of infrastructure and operational expertise to support science in both Polar Regions. The consortium is uniquely well positioned to significantly enhance Europe’s capabilities to undert
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The Culture of Gender-Based Violence in Early Modern Urban Society: Male-to-Female Spousal Abuse in Eighteenth-Century Madrid in a Global Context' under Horizon Europe.

assistant: **Concept**

Gender-based violence is now recognized as a global social problem. Worldwide figures on the number of women killed by male spouses reflect the magnitude of the phenomenon. However, its impact was greater in the past, as academic research in early modern Europe and America shows. Such was the case in Madrid. GENVIOMADRID examines the prevalence and evolution of gender-based violence in eighteenth-century Madrid to assess its impact, noting shifts and continuities in the way it was viewed and condemned by the courts and society. Violence against women in eighteenth-century Madrid remains an under-researched topic that requires further analysis. Based on extensive archival research and an interdisciplinary and comparative approach, GENVIOMADRID aims to fill this gap focusing on the study of marital violence against women and examining the case of Madrid in a wider European and global context. It favours a comparison between Madrid and major colonial cities in Spanish America to identify the social and cultural factors that influence changes in the incidence of, and responses to, gender-based violence in societies that, while very different, shared certain legal frameworks, judicial institutions and penal practices. By addressing key contemporary issues and placing gender-based violence in a historical context, it offers an empirical and theoretical background for tackling this social problem today. The action will be carried out at Harvard University in the outgoing phase, supervised by Prof. Tamar Herzog, and at the University of Cantabria during the return phase, under the supervision of Prof. Tomás A. Mantecón Movellán. It will provide interdisciplinary research training in early modern gendered legal and judicial history, colonial Latin American history, and global an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The neurobiological and computational origins of behavioral variability' (2014-2020) under Horizon 2020.

assistant: **Objectives**

Human behavior is inherently variable. Even when faced with the same exact choice options, we often take different actions. The causes for this inconsistency are unknown, but economic and cognitive theories assume this is due to noise that is injected when making a decision. However, I have recently demonstrated that noise might not just arise during the decision process, but that the learning process itself (i.e update of internal representations based on feedback) is subject to substantial and meaningful noise. Concretely, I have shown that noise during learning accounts for the majority of what is traditionally reported as ‘decision noise’. However, the neural mechanisms underlying this learning noise remains unknown. In this fellowship, I will examine the contributions of the locus coeruleus-noradrenaline (LC-NA) system to this learning noise. NA has previously been associated with decision noise and here I will test whether activity in the LC is the driving factor behind learning noise. I will use a cutting-edge real-time fMRI framework that allows to causally test whether ongoing LC activity directly influences learning noise. Moreover, I will examine whether this learning noise is relevant to impulsivity, which has previously been implicated in decision noise. This fellowship has the potential to overthrown the traditional view on behavioral variability in decision making and will provide a novel neurobiological, computational and psychiatric grounding for understanding why humans are consistently inconsistent.


**Keywords:** behavioral variability, locus coeruleus, learning imprecision, computational modeling, real-time fMRI, computational psychiatry
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Prediction and control of combustion instabilities for industrial gas turbines (PRECCINSTA)'.

assistant: **Concept**

Objectives and Problems to be Solved:The objectives of this project are to understand, predict and control the causes for combustion instabilities in lean premixed combustion, featured in modern, high efficiency industrial gas turbines with low emission levels. This includes the development of databases, validated numerical predictive tools and design rules to avoid such instabilities. The results will enable manufacturers to design new combustion chambers for gas turbines with improved reliability, improved efficiency, the ability to burn a wider range of fuels and reduced pollutant emission in comparison to today's engines. The end users will be able to monitor and operate their plants in a cost optimal way without sacrificing safety. Description of Work: In order to achieve the objectives, research and development is carried out comprising activities in the following areas:· basic instability mechanisms of lean premixed gas flames on a laboratory scale· interaction of aerodynamics, combustion and acoustic pressure waves leading to instability on tubular and annular rig scale combustion chambers· active and passive damping of combustion instabilities on tubular and annular rig scale combustion chambers· transition of methods and tools from rig scale combustion chambers to real engines with tubular/annular combustion chambers Expected results and Exploitation Plans: Major results are expected in the following areas:· Theory about the root causes of the onset of instability· Databases for stability limits of premixed lean gas flames· Analytical predictive tools for design· Knowledge about transferability of rig data into engine design· Design criteria for combustor dimensioning for high reliability The implementation of results in the development processes within the ma
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Homotopy Theory of Algebraic Varieties and Wild Ramification' to be submitted under Horizon 2020.

assistant: **Abstract**

The aim of the proposed research is to study the homotopy theory of algebraic varieties and other algebraically defined geometric objects, especially over fields other than the complex numbers. A noticeable emphasis will be put on fundamental groups and on K(pi, 1) spaces, which serve as building blocks for more complicated objects. The most important source of both motivation and methodology is my recent discovery of the K(pi, 1) property of affine schemes in positive characteristic and its relation to wild ramification phenomena. The central goal is the study of etale homotopy types in positive characteristic, where we hope to use the aforementioned discovery to yield new results beyond the affine case and a better understanding of the fundamental group of affine schemes. The latter goal is closely tied to Grothendieck's anabelian geometry program, which we would like to extend beyond its usual scope of hyperbolic curves.There are two bridges going out of this central point. The first is the analogy between wild ramification and irregular singularities of algebraic integrable connections, which prompts us to translate our results to the latter setting, and to define a wild homotopy type whose fundamental group encodes the category of connections.The second bridge is the theory of perfectoid spaces, allowing one to pass between characteristic p and p-adic geometry, which we plan to use to shed some new light on the homotopy theory of adic spaces. At the same time, we address the related question: when is the universal cover of a p-adic variety a perfectoid space? We expect a connection between this question and the Shafarevich conjecture and varieties with large fundamental group.The last part of the project deals with varieties over the field of formal Laurent series
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Applying state of the art smart sensor technology and Structure from Motion (SfM) photogrammetry for quantification of large wood (LW) movement processes and accumulation assessment in fluvial systems' (SfM).

assistant: **Innovation**

Large wood (LW) plays an important role in fluvial systems as it moderates stream power, regulates sediment transport and provides habitat for fish and other living organisms. Besides the beneficial effects of a balanced wood budget in rivers, challenges arise for abundant quantities of accessible LW. Large quantities of wood show negative effects on stream ecology, river-crossing infrastructure and flood mitigation. The sudden and disastrous occurrence of LW during floods regularly affects communities and stream systems all over the world. Due to a lack of applicable methodologies in LW research little is known about transport dynamics of wood in rivers to date. In order to expand the current understanding of flow-sediment-wood interaction processes, especially at higher flow rates, specific and profound research is required. This project aims to utilise state of the art technologies for the application in nature sciences. Nine-degree of freedom (9-DoF) smart sensors are implanted into wood logs ‘SmartWood’, to capture complex movement processes in-situ. Furthermore, Structure from Motion photogrammetry is applied for the generation of 3D LW accumulation models, on a basis of 2D images, for precise volume, porosity and surface texture evaluation. The innovative methodologies allow for novel insights into LW movement behaviour and for quantification of wood deposits, which are often obstructing and diverting the flow. An improved understanding of LW movement processes is essential to better predict arising impacts on channel morphology, river-crossing infrastructure and environment. Gained results will contribute in a more reliable risk assessment for wood prone stream systems, advanced river and forestry management strategies under consideration of LW conveyance and fi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'European Research Infrastructures for Nuclear Data Applications', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Different concepts involving critical (fast) reactors or subcritical accelerator-driven systems are being studied in view of their transmutation capabilities. These design studies imply high demands on the underlying nuclear database. The need for improved nuclear data has been expressed in the Strategic Research Agenda of the SNE-TP ( Sustainable Nuclear Energy Technology Platform).The accurate knowledge of neutron and proton induced nuclear reactions in the fast, intermediate- and high- energy domains (En = 1keV to 500 MeV) is of crucial importance for predicting the capabilities of reducing the inventory of plutonium, minor actinides, and long-lived fission products. In the past, this energy domain was not investigated with high priority because of minor importance for conventional light-water reactors. An additional challenge is the tightening demand on the accuracy of the data, especially for assessing criticality safety aspects and designing fuels for very high burn-up.The ERINDA project aims for a coordination of European efforts to exploit up-to-date neutron beam technology for novel research on advanced concepts for nuclear fission reactors and the transmutation of radioactive waste. Such waste is already existing in appreciable quantity due to the year-long operation of existing nuclear reactors and it will eventually also be generated during the running of new reactor types – albeit they can be optimized to produce much less of it. Research to the aim of finding techniques optimized for a strong reduction of nuclear waste can already be performed at existing nuclear facilities from the consortium proposed in this proposal.The main objective is to provide adequate transnational access to the infrastructures. The consortium will also provide funding for scienti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Motif in T cells for the Prediction of INTeractions' (MT-PoINT).

assistant: **Innovation**

T cells are a key element of the human immune system. Upon binding to antigenic peptides (called T cell epitopes), T cells can induce the death of infected cells or prime and regulate other immune cells. In cancer immunotherapy treatments, T cells are genetically re-engineered to recognize cancer epitopes and destroy malignant cells. Unfortunately, it still remains challenging to determine which T cells can target a specific epitope, both from a computational and experimental point of view. This limits mechanistic understanding of T-cell-mediated immunity and translational applications for disease treatments.Thanks to advances in high-throughput sequencing technologies, sequence data of T cells coupled with their cognate epitopes are accumulating at an unprecedented pace, offering unique opportunities to develop data-driven T cell-epitope interaction predictors.The goal of the MT-PoINT project (Motif in T cells for the Prediction of INTeractions) is to identify patterns in T cells sequences that underlie the binding specificity, interpret them at the structural level, and to develop sequence-based predictors of T cell-epitope interactions (Aim1) with a special focus on T cells targeting cancer epitopes (Aim2). My project will capitalize on a unique dataset of publicly available and in-house generated data that was not available in previous studies, and T cell sequence data from cancer patients of Lausanne University Hospital will allow me to benchmark the in-silico predictors in a clinically relevant setting. Accurate predictions of TCR-epitope interactions can narrow down the list of T cell candidates for personalized cancer immunotherapies, and significantly accelerate cancer immunotherapy clinical developments.


**Keywords:** computational immunology,  computational