RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Multitasking Nanoparticles for Intracellular Bioimaging and Biosensing' in the context of a Horizon 2020 call.

assistant: **Objectives**

The development of specifically designed nanomaterials for advanced medical applications such as theranostics has become a major technical challenge with great potential societal and economic outcomes. Nanomedicine and related techniques hold great promises for improved diagnostic and treatment of widely spread diseases such as cancer. This project, entitled NanoIntra, aims at developing novel multitasking nanoparticles as advanced tools for highly localized and ultrasensitive intracellular imaging and biosensing. These nanoprobes should provide new insights in the spatial and temporal processes at play in live cells and therefore reveal part of their mystery. Such functional objects are achieved through the design of a complex architecture which involves quantum dots as bright and stable luminescent markers encapsulated in a protective silica matrix. These nanoparticles are combined with plasmonic nanocrystals, which offer new strategies for their photothermally induced intracellular delivery. The targeting and imaging of specific subcellular structures is then achieved thanks to proper surface functionalization of the nanoparticles. In addition, the plasmonic nanocrystals also allow these nanoparticles to be used as Surface Enhanced Raman Scattering (SERS) biosensors. Finally, for a higher control on the use of such nano-biosensors, optical tweezers are used to purposefully manipulate and position the nanoparticles inside the cells at the region of interest. Besides their application in cell labeling and biosensing, these functional nanoparticles have tremendous potential applications in the fields of theranostics, nanomedicine and nanobiophotonics, and NanoIntra constitutes a first step toward the development of a full lab-on-a-particle. Thus, through the synthesis a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Aerodynamic Lift force of Trains subjected to cross winds—get it right!' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

A European-wide move to standardize the criteria for certification of railway vehicles has lead to the development of regulations for rail operators regarding velocities and pressures generated by trains and on train in cross winds. There are two approved methodologies currently used in these regulations; physical modeling using the wind tunnel experiments and numerical modeling using computational fluid dynamics (CFD) techniques. Although there are different types of CFD techniques, yet all of them suffer the lake of accuracy in predicting the values of the experimental lift force resulting on either overestimation or underestimation of the rolling moment coefficient. The aim of this innovative Fellowship is to develop an accurate numerical technique based on the steady Reynolds Average Navier Stocks (RANS) capable of accurately predict the aerodynamic forces. The methodology will be based on wind tunnel experiments, moving model testing and different types of steady and unsteady CFD techniques. In this project we will investigate for the first time the effect of surface roughness on the lift force prediction of a train subjected to cross wind. Building on the complementary skills of the Experienced Researcher (ER) (numerical modeling) and the Beneficiary (CFD & physical modeling), we will extend significantly the existing knowledge of modeling trains on smooth surface to include a novel numerical technique to simulate the surface roughness and hence better estimate the lift force coefficient. Our work will be validated using wind tunnel experiment at POLIMI, ITALY and underpinned with those at our industrial collaborator, Interfleet and academic partner Chalmers, Sweden. Success will define improvements to prediction of the lift force coefficient in both physical expe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Establishing services enhancing the innovation management capacity of SME's in the Enterprise Europe Network' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Main task is to deliver Key Account Management services to SME beneficiaries of the EIC pilots under H2020, in addition to offering  Enhancing the innovation management capacity of SMEs, focusing on particularly promising SMEs in enhancing their innovation management capacities. The services are aimed at SMEs in Iceland with a great potential for international growth, but lack knowledge, skills or ability to manage innovation activities. Highly qualified staff of Enterprise Europe Network at the Innovation Center Iceland possesses the skills required and in-depth knowledge of the support required to enable companies to reach their potential.


**Keywords:** SME Instruments, FET-Open, FTI, Key Account Management, Innovation Analysis, Innovation Management,  Innovation GAP Analysis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Religion and Its Others in South Asia and the World: Communities, Debates, Freedoms'.

assistant: **Objectives**

Those who question or do not conform to dominant local religious tradition(s) and/or religion as such have, of course, faced serious problems and difficulties in a number of different historical periods and locations. This project examines the forms in which individuals and communities raise, in the open or in more hidden transcripts, questions over the dominant religious norms in South Asia. This project is also interested in how such people are being targeted as distinct minorities by various religious and political groups. However, the effects of these encounters extend beyond this region: a significant number of community members now seek asylum in European countries. In consequence, these countries are now debating whether, or to what extent, varieties of religious non-conformism can be legitimate reasons for granting asylum.While much recent academic work has focused on religious revivalism and reformist movements, critical engagement and sceptical attitudes towards dominant religious norms in South Asia are so far under-researched. A key aim of this study is to correct this absence and thereby to transform our understanding of the kinds of positions, individuals and communities that flourish but also, and critically, face challenges and provoke social contentions in South Asia. It will provide three national ‘deep contextualisations’ of debates and criticism faced by secularists and religious sceptics in South Asia, asking: What are the specific circumstances in which criticism targeting these communities and positions evolve? This study also investigates the assumptions that inform European countries’ responses to cases in which asylum is sought on the basis of claimants’ religious nonconformism, and also those informing advocacy work performed by global secular
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Biomaterials for Tracheal Replacement in Age-related Cancer via a Humanly Engineered Airway' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Age-related cancers, especially of the trachea, are neoplastic lesions that significantly impact upon the lives of thousands of European patients each year. Unfortunately, most present with inoperable lesions for which median survival is less than 12 months. Based on our previous clinically successful experiences with in vivo completely tissue engineered tracheal replacement in benign tracheal diseases, we recently applied this technology in 2 patients with otherwise inoperable primary tracheal cancers. The successful observed outcome confirms the unique opportunity to scale-up an effective therapeutic approach into a widely accessible clinical technology, which could enhance not only the quality of life but even cure otherwise untreatable patients. However, a limitation of our current technology is the time it takes to re-populate the decellularized trachea. This may prove critical in the case of cancer patients. Further, the size of the transplant is currently limited due to the fact that the transplanted tissue needs to be efficiently and rapidly vascularised to prevent necrosis in vivo. To surmount these limitations, we aim to: i) improve our current technique of in vivo tissue engineering human tracheae in a small number of patients and subsequently begin a formal clinical trial, ii) develop pharmacological approaches to activate endogenous stem cells, stimulate tissue regeneration and vascularisation in situ, iii) develop a synthetic tracheal scaffold using a novel nanocomposite polymer as alternatives to natural human scaffolds and iv) develop good medical practice manufacturing process for safe, efficient and cost effective commercial production. This research project is aimed to define a robust airway implantation technique assuring a better outcome for thousan
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'LAboratory and Modelling studies to UNderstand Isoprene Oxidation' in the context of a Seventh Framework call.

assistant: **Objectives**

Recent field and laboratory evidence points towards a significant failure in our understanding of the atmospheric chemistry of isoprene in low NOx conditions and notably its impact on OH, significantly inhibiting our understanding of the atmosphere-biosphere-climate system. The multidisciplinary LAMUNIO proposal, including technique development, laboratory and chamber studies and modelling evaluation, will be a major step forward to innovatively investigate isoprene chemistry.  LAMUNIO contains three workpackages looking at interferences in the FAGE technique for OH observation, particularly in environments dominated by biogenic emissions; studies of isoprene oxidation focusing particularly on OH and carbonyl measurement to validate proposed mechanisms; new techniques to study HO2 reactions relevant for low NOx chemistry. This proposal is timely and will provide underpinning laboratory studies to validate both measurement techniques and the proposed mechanisms that seek to explain the unexpected observations of high OH concentrations in environments dominated by the oxidation of isoprene in low NOx conditions. OH concentrations control the oxidative capacity of the atmosphere influencing important local (air quality) and global (methane concentrations and hence radiative forcing) issues. LAMUNIO will provide world class research and training opportunities and the proposed work is facilitated by the unique breadth of knowledge and infrastructure available at the University of Leeds.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Revealing enhancer-derived RNA (eRNA) transcriptome: eRNA processing and biogenesis during neuronal stimuli-activated transcription' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Enhancers are short distal cis-regulatory DNA regions that drive expression of a gene. However, enhancers do not function exclusively as DNA entities. Activated enhancers are transcribed by RNA polymerase II (RNAPII), which produces enhancer-derived RNAs (eRNAs). Production of eRNA creates additional trans-regulatory mechanisms facilitated by DNA-RNA, RNA-RNA, or protein-RNA interactions. Due to eRNAs fast degradation rates, and lack of robust and standardized sequencing methods, reports about the molecular nature of eRNA molecules and their processing are conflicting, making mechanisms of gene regulation by eRNA controversial. Even less is known about co- and post-transcriptional processing of eRNA. This project aims to overcome the controversy and fill the knowledge gap by studying a well-defined experimental system, cultured rat cortical neurons, and activation of immediate-early gene (IEG) response, perturbing the core eRNA endonuclease and combining this with eRNA-tailored sequencing, computational and biochemical methods. The developed integrative approach will reveal molecular features of eRNA molecules and their precursors genome-wide, opening the opportunity to study eRNA biogenesis to further understand molecular mechanisms behind the eRNA-mediated gene regulation.


**Keywords:** RNA polymerase II, enhancer-derived RNA, eukaryotic transcription, enhancer
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Metal-Foldamer Porous Frameworks' (MFPFs).

assistant: **Innovation**

The design and precise construction of protein-inspired nanostructures through folding and metal-directed self-assembly is a challenging yet potentially rewarding endeavor for the development of new classes of functional materials. Peptides have been well established as flexible starting points for the construction of bioinspired architectures with a high level of sophistication and precise control over morphologies and functions. Concurrently, the power of metal coordination to drive assembly has been extensively explored to design functionally versatile metal-organic frameworks (MOFs). Yet, the synthesis of such coordination networks by a process that would combine folding, self-assembly and metal coordination in aqueous media is still partially unaccomplished. Foldamers - artificial synthetic folded oligomers - possess the advantages of structural robustness and high programmability which bodes well for their use in the construction of well-defined higher-order nanostructures. The project will move a step forward towards the design, synthesis and structural characterization of metal-foldamer porous frameworks and will focus on foldamer sequence evolution and metal variation to influence the main features of the assembly (shape and catalytic property). The applicant has been trained in peptide synthesis and has acquired a high level of expertise in the design and structural characterization of peptide-based assemblies and advanced materials. He will join and bring his expertise to a host laboratory that has pioneered the design of oligourea-based foldamers as peptide mimics. Secondment in an internationally renowned group in the chemistry of metalloenzyme active sites and the design of bio-inspired catalysts will provide the appropriate combination of knowledge requir
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'A holistic design of secure vehicular networks: communications, data caching and blockchain services'.

assistant: **Objectives**

With the rapid development of future connected vehicles, Cyber Security has been gaining increasing importance to the connected systems that are fundamental to our society, health and welfare. It will be given priority to the upcoming areas, including autonomous systems and cyber-physical systems, etc. The SEEDS project sets an ambitious research agenda to fully exploit the potentials of V2X communications, data caching and blockchain services for revolutionizing the security and privacy of vehicular networks. Particularly the overall aim of SEEDS is to accelerate the transfer and deployment of research knowledge between European countries and third-country (TC) partners in order to realize a cross-layer design of reliable and robust security for V2X networks, and meet the challenging security requirements, that is confidentiality, integrity, privacy-preserving, trust and scalability. The technical approach is seeking is two-fold. One is to pursue a new design of spectrum efficient and decentralized approaches to address security challenges in physical layer communications and upper layer content disseminations by fully exploring the practical and theoretical analysis, dynamic nature of channels/traffic patterns and self-learning techniques, which provides the theoretic aspect of the project. Then, the second step is from the practical aspect, where the proposed security methods and their performance will be validated using large scale simulations and testbed provided by the TC partners. The proposed vehicular mechanisms are expected to facilitate an increasing number of vehicular applications with flexible availability, high confidentiality and robust integrity.


**Keywords:** vehicular communications and networks, cyber security, data centric networks, blockchain
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Open system for collaborative design' to be submitted under Fourth Framework.

assistant: **Abstract**

The project is concerned with multi-partner collaborative design optimisation. This is a key area for future European industrial competitiveness, requiring leading-edge capabilities to improve designs whilst significantly reducing costs and time-to-market. The project will develop a system for product optimisation based on multiple objectives. The most important feature will be flexibility and the ability to accommodate the many diverse techniques currently in use across European industry. Design problems from five major industrial sectors will define the requirements of the system and will validate its effectiveness for diverse industrial applications. The optimisation of a design is highly computationally intensive. The project will use existing HPCN technology and parallel solvers. The system will be developed in three distinct phases, synchronised with user trials in the aerospace, shipbuilding, domestic appliance, heating and diesel engine sectors.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Developing Computer Vision and Artificial Intelligence for best-quality and cost-effective live sports production and distribution' (OZeye).

assistant: **Concept**

OZ Sports has pioneered a production and broadcasting platform called OZeye, by using cutting-edge software technologies to remotely control camera robotics, and to enable unmanned production of football games to convert them into multi-formatted video streams for various platforms. Our automated solution results in 90% cost savings while providing 4K/UHD video quality that exceeds state-of-the-art. Our broadcasting ecosystem incorporates an experience-rich environment, where football fans connect using their mobile devices. This experience-rich ecosystem will generate fan engagement and adherence to the platform, powered by Augmented Reality technology to recreate a realistic atmosphere of attending a live football game. Today’s production and broadcasting solutions are a perfect fit for the best sponsored and monied football leagues and clubs of Europe - less than 1% off all the football played on the continent.  This leaves at least 11,900 European clubs without an opportunity to grow their fan base and earn revenues to auto fund their development. OZeye gives these local clubs the means to produce and broadcast their football matches to a worldwide audience. Our broadcasting platform opens the doors for any fan anywhere to watch their team at their leisure and convenience for the first time ever.Recently, we have seen the rise of digital broadcasters, though they still target the same segment of footballing leagues as the traditional linear TV networks had done before them for the past decades. If some of them incorporate automation in their production, they still do not provide a better-quality result for the viewing public, which we do, by addressing the whole value chain is what makes OZeye different.By the fourth commercialization year, we expect to install OZey