RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Advanced RF Transceivers for 5G base stations based on GaN Technology.' under Horizon 2020.

assistant: **Concept**

TA new generation of communications infrastructure is currently in development. The fifth generation (5G) communications technologies will provide internet access to a wide range of applications: from billions of low data rate sensors to high resolution video streaming. The 5G network is designed to scale across these different use cases and will use different radio access technologies for each use case.To support very high data rates 5G will use wide bandwidth spectrum allocation at mm-wave frequencies. The offered bandwidth at the mm-wave frequencies (above 24 GHz) is more than 10 times as large as that in the lower bands (sub 6 GHz). However, the move to mm-waves comes at a cost – increased path loss. This makes it extremely challenging to provide coverage at mm-wave frequencies.A partial remedy is to use beamforming to direct the radio energy to a specific user. For some deployment scenarios beamforming is not enough and the output power must also be increased. A major challenge is to bring affordable, high-performance mm-wave active antenna arrays into production. There is currently a market pull for this systems.The main objectives of the “5G_GaN2” proposal are substantial lowering the cost, power consumption and increase the output power of mm-wave active antenna systems. Advanced Gallium Nitride (GaN) technology will be used to get maximum output power and energy efficiency. High-volume and low-cost packaging and integration techniques developed for digital applications (CMOS) will be used.The capabilities of the developed technology will be shown in a set demonstrators. The application driven demonstrators will be used to guide the technology development towards maximum impact and exploitation in the post project phase. The consortium spans the complete value c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Execution of c-myc programed cell death, study in a cell-free system' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Research objectives and content Using a new approach to study apoptosis induced by the proto-oncogene c-Myc, we hope to prove that this process is under the control of non nuclear events. Our work should provide evidence that cytokines and the proto-oncogene Bcl-2 protect against these effects by modulating these non nuclear events. Focussed on the involvement of ICE-like proteases and their regulation during c-Myc induced apoptosis, _ll-free studies could provide numerous information concerning a pivotal role for these proteases in the cell death program . This study should precise the sequence of c-Myc induced cell death pathway. Our cell-free study could determine how Bcl-2 family and ICE/CED-3 family members interact. Training content (objective, benefit and expected impact) The interaction between c-Myc and Bcl-2 represent a novel type of oncogene cooperation of potential importance both in carcinogenesis and in the evolution of resistance in tumors. The availability of a cell-free system reproducing apoptotic events in vitro is a powerful tool to study biochemical events controlling programmed cell death. Unravelling of the molecular mechanisms involved in c-Myc induced proliferation and cell death pathways is important in the understanding of carninogenesis and in the development of their pharmacological control. Links with industry / industrial relevance (22) This project is open to collaboration with Tom Cittenden'group (Apoptosis Tech. Inc., Cambridge, MA, USA)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Innovative Track Systems'.

assistant: **Innovation**

InnoTrack is a unique opportunity to bring together rail infrastructure managers (IM) and industry suppliers, the two major players in the rail industry, and to concentrate on the research issues that will contribute to the reduction of rail infrastructure Life Cycle Cost (LCC). The EC White paper on Sustainable Transport calls for rail operators to: -Double passenger traffic and triple freight traffic by 2020 -Reduce LCC by 30% The Railway Business Scenario 2020 also calls for railways to capture 15% of freight and 12% of the passenger market. To achieve these objectives, investment alone is not sufficient, significant innovation and technology transfer is essential. This can only be achieved with very close cooperation between IMs and industry suppliers. It is essential that the IMs, as the end users, set out their priorities and needs, at a European Level, to solve the necessary problems for achieving the white paper objectives. This will be done by performing research on four key topics: -Track support structure -Switches and Crossings -Rails -Logistics for track maintenance and renewal To ensure that cost reductions can be consistently evaluated across Europe, InnoTrack will also devise an innovative generic methodology for LCC calculation, based on best LCC practices at EU level, to be used by all IMs across Europe. For each of the research topics, InnoTrack will: - Analyse the root causes of identified issues on a European scale taking into account the effect of different duty conditions whilst providing product and service solutions for cheaper and longer lasting tracks - Draw together common European specifications regarding Reliability, Availability, Maintainability and Safety (RAMS) combined with LCC - Provide innovative solutions to reduce failure rates and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Private Machine Learning' under Horizon 2020.

assistant: **Concept**

Machine learning algorithms are data-hungry, and perform better when exposed to more and more data. Such data is being collected in massive amounts by internet giants, and is often sensitive and private. Examples include the purchases and browsing history of users, their health data and exercise activity, locations they travel to and messages they type into their mobile phone. The amount of data being collected can be significantly reduced using cryptographic techniques, in particular, using secure multiparty computation. Secure computation enables mutually distrustful parties to compute a joint function of their inputs without revealing the inputs to one another. In this research, we will address secure computation techniques of machine learning tasks. The first task is private classification: One party holds a model trained on a sensitive dataset, and another party holds a sample and wishes to evaluate the model on that private sample. Our objective is to fulfill this task while achieving significantly stronger security notion than previous works, that is, security even if one of the parties deviates from the protocol specifications (malicious security). The second task is federated learning, a techniques that enables thousands of participants to train a neural network on their joint data but without revealing the data to one another. However, a recent work showed that such task is susceptible to injection of backdoors, and a user can manipulate the joint model to his/her own benefit, significantly reducing the usefulness of federated learning in practice. Our objective is to guarantee immunity to such injections. The two objectives will be achieved by improving specific cryptographic building blocks, and applying them for these applications. PRIMAL will speed up secu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Autonomous Trust, Security and Privacy Management Framework for IoT' (ARCADIAN-IoT), addressing dissemination and exploitation.

assistant: **Impact**

The deployment of IoT systems are increasing worldwide, but so does security incidents like ransomware and cyber-extortion, which are not sufficiently covered by current cybersecurity practices and will proliferate with upcoming technologies like 5G. At the same pace, attacks are becoming more sophisticated, requiring reinforced cybersecurity competencies, as well as more effective mechanisms for detection and mitigation of attacks. ARCADIAN-IoT established the goal to develop and make available an innovative, advanced framework for trust, security and privacy management in IoT systems to promote trustworthy IoT systems. ARCADIAN-IoT will accelerate the development towards decentralized, transparent and user controllable privacy in three real use cases: Emergency and vigilance using drones and IoT; Monitoring of grid infrastructure; and medical IoT devices for telemonitoring and follow-up of cancer patients. ARCADIAN-IoT aims to fill a gap in the IoT threat intelligence landscape by providing a novel IoT- specific Cyber Threat Intelligence (CTI) approach, which supports integrated, automated and privacy- preserved IoT threat information sharing. ARCADIAN-IoT will research distributed ledger technologies to enable decentralized trust management and will leverage on federated AI for effective cybersecurity solutions complying with privacy regulations. ARCADIAN-IoT will act as an enabler of IoT systems in future networks by including eSIM technology with over the air management support for devices, and to enhance identity management through trusted hardware – Root of Trust (RoT). ARCADIAN-IoT will enable a Chain of Trust (CoT) to address identity, trust and recovery considering the multiple entities in IoT systems: persons, IoT devices/objects and Apps/services. At last, A
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Prosumer Flexibility Services for Smart Grid Management' (Flex4Grid).

assistant: **Concept**

The advent of distributed power sources, such as photovoltaics and windmill plants, gave rise to energy prosumers (producers-consumers), which generate and consume electrical energy. Energy demand and energy generation by prosumers are volatile and can impact the grid infrastructure and stakeholders, but they can be flexibly adapted to thwart those impacts.Flex4Grid aims at creating an open data and service framework that enables a novel concept of managing flexibility of prosumer demand and generation, utilising cloud computing for power grid management and, opening DSO infrastructure for aggregator services. The system will be built up from existing ICT components developed by the consortium partners over many years in research projects on IoT and Cloud computing. This high maturity allows Flex4Grid to aim for a system prototype of TRL 7 which guarantees a maximum impact and competitiveness in the area of the smart grid challenge.The Flex4Grid system will include a) a data cloud service with anonymised interface and advanced security and privacy mechanisms for data exchange and service management, b) prosumer generation and demand flexibility, and c) a more viable business model to accelerate the deployment. The major innovations are a) opening the market for new entrants by secure and privacy enabling third party cloud data and energy management services, b) actionable common and multilevel data management and analytics services for Smart Grids, and c) the use of co-creation to bring end users into the value creation process.System validation will be carried out in real-world pilots in three live electricity networks with different scenarios ranging from deployment during smart meter rollout and retrofitting to large scale operation and federated demonstration of mul
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'European Macromolecular Crystallography Infrastructure Network 2' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Macromolecular X-ray crystallography can only flourish in Europe if the means and methods that are being developed at our centres of excellence, are disseminated efficiently. We propose to promote this process, and to facilitate access to research infrastructures, by organising three different types of activities in an EU spanning Network. (1) Method based schools aimed at bringing together young scientists will be an excellent instrument for spreading expert knowledge and creating new, informal networks between institutes throughout the EU. (2) Teaching workshops will allow young scientists to be coached by specialists in the latest techniques and methods in a hands-on environment, and form a vital addition to the larger-scale schools. This will spread good practice, common protocols and collaboration. (3) Integration workshops will promote the development of new ideas and procedures by bringing together experts in the field. Further collaborations between these expert groups will be promoted by travel-funds for short time visits. All these activities will be organised and directed in co-ordination meetings of participants of the proposed Network.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Camelina & crambe Oil crops as Sources for Medium-chain Oils for Specialty oleochemicals'.

assistant: **Innovation**

The COSMOS proposal aims to reduce Europe’s dependence on imported coconut and palm kernel oils and fatty acids and castor oil as sources for medium-chain fatty acids (MCFA, C10–C14) and medium-chain polymer building blocks. These are needed by the oleochemical industry for the production of plastics, surfactants, detergents, lubricants, plasticisers and other products. In COSMOS, camelina and crambe will be turned into profitable, sustainable, multipurpose, non-GMO European oil crops for the production of oleochemicals. Seed properties will be screened and optimised through genetic techniques aiming at high yield, low resource inputs, optimization of the value generated from vegetative tissues and fatty acid profiles adapted to industrial needs. Large-scale field trials will be performed at different locations in Europe to assess the potential of the crops in terms of cultivation practices, seed yield, oil content, ease of harvesting, and resource inputs. Extracted oils will be fractionated into various fatty acid types (monounsaturated versus polyunsaturated) by selective enzyme technologies and extraction processes. The monounsaturated long-chain fatty acids so obtained will be converted to MCFA and high-value building blocks for bio-plastics and flavour and fragrance ingredients through chemical and enzymatic chain cleavage processes. The ω3-rich PUFA fraction will be purified for use in food and feed ingredients. Vegetative tissues such as straw, leaves and press cake will be fed to insects producing high-value proteins, chitin and fats. Insect fats and proteins will be isolated and prepared for use in food and feed products. The overall economic, social and environmental sustainability as well as life cycle of the whole value chain will be assessed. The impact of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Diversity and ecological function of benthic nitrate reducing populations along an estuarine nitrate gradient' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

Eutrophication of estuarine and coastal ecosystems due to increased anthropogenic inputs of nitrogen is an increasing problem. Benthic microbial processes influence nitrogen loads particularly by denitrification removing up to 50% of the load. However, a product of nitrate reduction is the greenhouse gas nitrous oxide. Understanding the benthic processes involved in the removal of nitrogen, or the formation of nitrous oxide, is important for the management and reduction of nutrient load to coastal waters and greenhouse gases emissions. Nitrate reduction in estuarine sediments is mediated by two main functional groups of bacteria.Bacterial denitrifiers reduce nitrate or nitrite to gases subsequently lost from the aquatic environment, while nitrate ammonifier s reduce nitrate to ammonium that remains in the system. The first step in both processes is identical (nitrate reduction to nitrite) and is catalysed by one of the two types of nitrate reductase enzyme (NAR and NAP) that show different physiological roles depending on the bacterial functional group involved and environmental conditions.Aim is to study the spatial distribution and seasonal changes of genes coding for NAR and NAP, and their expression level, in the benthic nitrate reducing community along an estuarine nitrate concentration gradient and relate these to process rates. To accomplish this, the researcher will apply modern molecular (eg. real time PCR) and biogeochemical (eg. stable isotopes) techniques in an inter-disciplinary way that will strengthen his scientific skills. The results will allow to test the hypotheses that changes in the concentrations of electron acceptors result in differences in the distribution of functional genes and groups of nitrate reducers along an estuary and that differences i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Revolutionising peptide-based drug discovery with high-throughput mimotope mapping' (PepVerse).

assistant: **Innovation**

Peptide-based drugs offer distinct advantages over existing molecular therapeutics, such as their ability to engage targets that have proven challenging for small molecules, and their capability to penetrate cells and modulate intracellular targets, which conventional biologics cannot achieve. However, despite this potential, the development of peptide-based medicines has lagged due to the lack of high-quality, large-scale protein-peptide interaction datasets essential for rational AI-driven peptide design. During the ERC Consolidator Grant DiProPhys, we developed a platform that can profile protein/peptide interactions at scale. As part of the PepVerse project, we will leverage this platform to generate proof-of-concept data for commercial exploitation. Specifically, we will generate binding data for three high-value therapeutic targets that currently lack orally available drugs due to difficulties in identifying non-peptidomimetic small molecule binders. These data will not only validate the platform’s ability to discover binders but will also provide specific starting points for high-value drug discovery programmes. Moreover, the data will showcase the platform’s potential to create the world’s largest protein/peptide mimotope dataset foundational for advancing any peptide-based drug discovery programme --- a goal we aim to achieve with the help of private capital. In addition to generating these validation data, which are key for fundraising and translating the technology to a commercial entity, our other critical objectives for the project include establishing solid IP protection for the technology and building relationships with key stakeholders, such as advanced library providers and pharma partners. By the end of the project, we aim to have generated robust vali