RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'European Joint Programme on Radioactive Waste Management'.

assistant: **Innovation**

Following decades of RD&D in support of the safe management and disposal of radioactive waste, and building on the preparatory work of the recent EC JOPRAD project, a European Joint Programme on Radioactive Waste Management (EURAD) is now proposed to coordinate activities on agreed priorities of common interest between European Waste Management Organisations (WMOs), Technical Support Organisations (TSOs) and Research Entities (REs). Such Joint Programming will complement National RD&D Programmes, by jointly establishing and carrying out activities jointly where there is added value at the European level. It is the logical next step in deepening collaboration between European actors in the field of radioactive waste management (RWM). It builds on existing and emerging networks of European actors (IGD-TP, SITEX and REs network), preceding coordination and support actions (in particular, SecIGD2, SITEX-II project and JOPRAD). The Joint Programme will generate and manage knowledge to support EU Member States with their implementation of the Directive 2011/70/Euratom (Waste Directive), taking into account the different magnitudes and stages of advancement of Member State National Programmes. This will encompass:• Supporting Member-States in developing and implementing their national RD&D programmes for the safe long-term management of their full range of different types of radioactive waste through participation in the RWM Joint Programme; in particular:• Consolidating existing knowledge for the safe start of operation of the first geological disposal facilities for spent fuel, high-level waste, and other long-lived radioactive waste, and supporting optimization linked with the stepwise implementation of geological disposal; and• Enhancing knowledge management and transfer b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Creating a solid configuration-and test-management infrastructure to improve the team development of critical software systems' (CONFITEST).

assistant: **Concept**

The main business of TeSSA is giving extensive and unlimited support for building business solutions". A great part of these solutions are IT solutions. The core activities in TeSSA are developing AND implementing quality software systems.We are aware that testing procedures, completed with version and configuration management are a real need to deliver quality software products in time. Another important reason to implement these procedures is teamwork. More and more people are working together on the same product. Working as a team on the same project, means introducing more procedures for testing and configuration management, otherwise the existing problems will escalate. More control and confidence in the development environment results in a more stable atmosphere to work in. This reflects on all levels, from programmer to management. The people TeSSA invested in are very important for the continued existence of TeSSA.THE EXPERIMENTThe experiment aim at a stepwise process improvement towards a fully controlled process with standard built in test procedures and configuration (version) control management on different levels.The experiment will start by appointing 1 person, responsible for testing and quality improvement. He will be the driving force behind the experiment. Workgroups consisting of analysts and programmers will think of the best possible plan to implement the control management.The status of the baseline is well known and registered, so the results of this improvement can be measured very well and disseminated to other organisations developing the same kind of software. EXPECTED IMPACT AND EXPERIENCEOrganisational procedures in the domain of configuration and test-management will help the project leader to control the development process. The following
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'General-Purpose Programmable Evolution Machine on a Chip' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Despite recent advances in in vivo directed evolution techniques and the interest they have attracted so far, their impact in applied biotechnology is limited because of their limitations in programmability, selective drivers, cost and scalability. Here, we propose to construct a general-purpose programmable evolution machine able to quickly evolve new biomolecules or phenotypes in bacterial cells. The proposed device will use existing phage technology and synthetic regulation to engineer a programmable directed evolution machine able to produce biomolecules or biocomputational functionality two orders of magnitude faster than conventional techniques, while consuming fewer consumables. In its core, living matter will be subject to combinatorial search algorithms that will exploit large numbers of small, separate, bacterial populations. Each one will contain phage that evolve under different custom fitness selections. The different phage will then be recombined according to combinatorial optimization strategies. The software and hardware design of our device is inspired by microprocessor manufacturing practice. Hence, in addition to the genetic devices for phage engineering, mutation, recombination and selection, we will develop: i) fluidic modules for cell and phage growth, ii) their hardware primitives, iii) a custom instruction set architecture, and iv) a high-level language with its compiler. We will demonstrate the operation of our device by engineering site-specific ribonucleases and nucleases with real-world applications, such as anti-HIV activity. We will also develop applications for new type of distributed bacterial computing using phage communication. We will thus put in place the foundations and approaches for this radical living technology that will impact I
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'LARGE-SCALE SOLAR THERMAL SCHEME IN AN URBAN ECOLOGICAL HOUSING AREA' (EKOVIIKKI).

assistant: **Concept**

The project aims to demonstrate for the first time the usefulness of large-scale solar heating in Finland. Also, the applicability of large-scale active solar integrated into a sustainable urban city-planning scheme (Helsinki-Ekoviikki) will be demonstrated. Eight solar systems with a total area of 1246 m² will be installed. Main innovation lies in the following aspects: strong integration of solar to all levels of the process (technical, building/architecture, construction), building integration optimized solar collector technology, a low-flow operating strategy with strong storage stratification increasing collector output. Energy savings 540 MWh/a and cost of heat produced 90-100 ECU/MWh. This project strives to demonstrate a major reduction in the solar price compared to existing practices in Finland.The main innovation lies in three aspects:- multi-level integration of a large solar scheme into an urban ecological (low-energy) housing area.- improved storage concept based on low-flow strategy and vertical stratifiers.- building integrated optimized solar collector design.Solar aspects and the requirements will be integrated to each phase of the building project to enable optimum system interfacing. The improved storage concept is based on increasing the level of stratification of the water tank through a novel vertical plastic header pipe with membrane valves that open on very small pressure differences. The big module collector (10 m² each) is designed for larger collector areas to be mounted on building structures.The solar heating project will be realized in Helsinki Ekoviikki area (60°N). The housing site has a built area of 64000 m² and in half of this subject to solar heating to be realized in this project.Ekoviikki is an urban ecological housing area to be b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Euroconference on 'Molecular Motors'' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

Support is requested for a Euroconference on Molecular Motors, to be held at Alpbach, Austria, in April 2001. This conference will follow the highly successful one, which we held there in 1998. The title 'Molecular Motors' refers to those molecules in the living cell, which use chemical energy (for example, from the splitting of ATP) to produce work. The best-known such motor is the protein myosin, which powers muscle contraction. However, it has become apparent in the last 10-15 years that the cell contains a huge variety of such molecular machines, with diverse and essential functions. The field of molecular motors aims to understand both their common principles of operation and the specializations of individual motors. This research lies at the intersection of many fields biochemistry, biophysics, cell biology, physics) and the results have major implications for medicine and for industrial applications.The conference will be for the presentation of the most recent, still unpublished research on motorsSessions will be structured so as to maximise interdisciplinary group discussion of new results, clarification of controversial issues and the development of new concepts and research directions. These sessions will be complemented by organized poster sessions for detailed presentation of experimental work. The meeting will have an informal character, favourable also for private discussion and for promoting international collaboration. The participants will be active researchers in the area of molecular motors fom European and non-European countries; they will be selected on the basis of their ability to contribute actively to the meeting. Keynote speakers will be internationally known experts, the leaders in their respective areas of specialization. Financial support i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Data-driven Inference of Models from Embodied Neural Systems In Vertebrate Experiments'.

assistant: **Innovation**

A major challenge in cognitive neuroscience is to understand how behaviour arises from the dynamical interaction of an organism’s nervous system, its body, and its environment. Understanding embodied neural activity involves the resolution of various conceptual, technical and methodological issues in explaining how living organisms self-organize at many levels (from neural bio-chemistry to behaviour and learning). Currently, two important obstacles hinder this endeavour: the difficulties in recording neural activity in behaving animals, and the lack of mathematical tools to characterize the complex brain-body-environment interactions in living organisms. In this project we will address current limits by implementing an interdisciplinary combination of novel animal behaviour neuroimaging setups and large-scale statistical methods, with the goal of recording and modelling whole-brain activity of locomoting vertebrates. We will study fictively swimming larval zebrafish during active behaviour in a pioneering experimental setup, recording neural activity utilizing light-sheet microscopy for calcium imaging in different virtual reality scenarios involving sensorimotor manipulations. In this setup, we will collect data from the distributed neural circuits that integrate sensory signals from the environment (exafferent input) and their own movements (reafferent input), as well as plastic processes of habituation to new sensorimotor contingencies. From this data, we will infer large-scale generative models (i.e. models capable of yielding synthetic data resembling the studied phenomena) of embodied neural circuits by complementing dynamical models and techniques from statistical mechanics with innovative information theoretic and Bayesian inference methods and approximations fo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Why casein is a major food allergen?' (CASALL) under Sixth Framework.

assistant: **Objectives**

Food allergy is a major health concern in Europe since 6 to 8% of children are suffering from it. Furthermore, the prevalence of this pathology has significantly increased during recent years. Among the foods responsible for allergy, milk is one of the most important especially in infants and young children. The proteins involved in milk allergy are the whey proteins and the caseins. During the recent years, sensitivity to casein has increased in terms of both frequency and intensity of IgE response, which is quite surprising since caseins are known to be rapidly and extensively degraded by proteolytic enzyme during digestion, limiting their allergenicity. The objective of the present project is therefore to understand why casein is a major food allergen.Several hypotheses may explain this phenomenon and will be investigated during this project:(1) role of casein phosphorylated sequences resistant to digestion,(2) protection of caseins from digestion by lipids,(3) impact of technological processes on case in digestibility.This 3-year project will be realized thanks to a close cooperation between the Institute of Food Research (IFR) in Norwich UK (Drs Mackie and Mills) and the National Institute for Agricultural Research (INRA) in Poligny France (Dr Dupont). Most of the technical work will be done by Dr. Dupont during a one year stay at IFR where the applicant will deepen his knowledge and expertise in the food allergy area and will acquire technical skills, in particular proteomic techniques, he will need for his future scientific projects. He will use an in vitro digestion gut model previously developed at IFR that he will be able to transfer to INRA after his stay at IFR.Finally, he will learn about EU project management, as well as networking with other centres invol
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Holistic Approach for Driver Role Integration and Automation Allocation for European Mobility Needs'.

assistant: **Innovation**

The HADRIAN project represents a human-centered revolution in the definition of driver roles in automated driving (AD) that starts with human mobility needs within the larger framework of European future mobility visions in the areas of shared, individual, and freight mobility. Holistic driving system solutions are conceptualized based on realistic arrangements of vehicle and infrastructure capabilities matched with human capabilities to achieve safe, acceptable, and trustworthy use of AD functionality and transitions between AD levels.The HADRIAN project focuses on the utility of dynamically adjusting (fluid) human machine interfaces (HMI) that take environmental and driver conditions into account to provide adaptive signals, information, or transfer authority that the driver needs to safely transition between AD levels. For this fluid HMI (f-HMI), real-time driver status models, novel sensor and information fusion methods & algorithms, as well as decision logic algorithms for contextually sensitive interventions and information offerings will be developed. A (fluid) tutoring system will provide a step-wise training of the driver and enable calibrated levels of trust.The HADRIAN project aims to increase the safety of AD level transitions by 85 % compared to traditional, non-adaptive HMIs, and achieve acceptability of 95%. Nineteen human participant studies, covering a broad range of driver demographic and cultural factors, will explore and evaluate f-HMI concepts and driver monitoring methods in driving simulators and field demonstrations. Field demonstrations will be performed using the full range from light to larger passenger vehicles and freight vehicles/trucks (L, M, and N class).Eventually, the HADRIAN demonstrators and effectiveness metrics will be translated in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Formalisation of Constructive Univalent Type Theory', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

There has been in the past 15 years remarkable achievements in the field of interactive theorem proving, both forchecking complex software and checking non trivial mathematical proofs.For software correctness, X. Leroy  (INRIA and College de France)has been leading since 2006 the CompCert project, with a fully verified C compiler.For mathematical proofs, these systems could handle complex arguments,such as the proof of the 4 color theorem or the formal proof of Feit-Thompson TheoremMore recently, the Xena project, lead by K. Buzzard, is developing a large library of mathematical facts, andhas been able to help the mathematician P. Scholze (field medalist 2018) to check a highly non trivial proof.All these examples have been carried out in systems based on the formalism of dependent type theory, andon early work of the PI. In parallel to these works, also around 15 years ago,a remarkable and unexpected correspondance was discovered between this formalismand the abstract study of homotopy theory and higher categorical structures.A special year 2012-2013 at the Institute of Advance Study (Princeton) was organised bythe late V. Voevodsky (field medalist 2002, Princeton), S. Awodey (CMU) and the PI.Preliminary results indicate that this research direction is productive,both for the understanding of dependent type systems and higher category theory, and suggest several crucialopen questions. The objective of this proposal is to analyse these questions, with the ultimate goalof formulating a new way to look at mathematical objects and  potentially a new foundation of mathematics.This could in turn be crucial for the design of future proof systems able to handle complex highly modularsoftware systems and mathematical proofs.


**Keywords:** Type Theory, Interactive Theorem Proo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Energy-Use Minimization in Residuals Management in the Personal Care Product Industry'.

assistant: **Innovation**

All industries produce residuals during normal operation, and the handling of such materials is a regular component of business activity. Traditionally, such residuals are treated prior to disposal; however, most residual processing methods are designed to reduce residual mass rather than minimize energy use, which is a growing problem as the cost of energy continues to rise. As an example up to 10% of the energy cost of a personal care product manufacturing plant (PCP) is used in residual management. Given this high cost, residual handling methods must be re-evaluated and made more energy efficient both to reduce costs, but also to make these processes more environmentally friendly. The purpose of ENERMIN is to develop alternate residuals management technologies for the PCP industry that will broadly reduce energy use. Although this is valuable technical goal, the second major intention of this work is to stimulate interactions between a world-leading academic group (Newcastle University; United Kingdom), a large corporation (L’Oreal Industries; France), and a SME (ACS-Umwelttechnik; Germany) while generating technologies that can be translated broadly to small and large operations inside and outside of the PCP industry. Specific technical approaches for energy minimization will include retrofitting existing aerobic systems to lower air needs; source separation of carbon-rich residual streams for pre-processing prior to aeration, and a new focus on waste-to-energy technologies (i.e., anaerobic systems). The broad goal here is to develop residual management systems that convert residuals into “resources” that produce rather than use energy, possibly by enhanced methane generation as a biofuel. Finally, this project will permit the extension of ECOSERV, a current FP6 pro