RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'REGIONAL DIFFERENCES IN LIVESTOCK PRODUCTION SYSTEMS : DEVELOPMENT OF PROTOCOLS AND METHODOLOGIES FOR POLICY EVALUATION AND IMPACT ON RURAL DEVELOPMENT' (1994-1998).

assistant: **Innovation**

The objectives of the concerted action are to establish a network ofresearchers throughout the EU to define and agree protocols for describing and characterising livestock production systems across the EU so that the impacts of changes in policy on the livestock industries and on the rural economy can be quantified on a regional basis. The project will a) identify the needs of policy research in evaluating the impact of policy, b) identify sources and types of data needed to construct a spatially explicit regional description of livestock systems, c) devise a protocol and methodology for describing the regional variation in livestock systems, d) promote interaction between researchers from a range of disciplines including policy researchers, animal scientists, socio-economists and geographers and a) promote dialogue between policy makers and researchers. Some progress has been made in developing spatially explicit descriptions of arable farming systems, but no attempt has been made to do so for livestock systems across the EU, although several national initiatives are emerging and it is timely to initiate a concerted action to ensure coordination of these activities. Four sub-groups of researchers (each with approximately 10 members) will be set up, each led by an experienced researcher and under the general direction of the coordinator. The sub-groups will a) identify policy research requirements, b) devise a protocol and methodologies and identify data needed for the future@development of spatially explicit models to assess the effects of policy on livestock systems, c) identify indigenous expert knowledge of livestock systems and d) identify the economic and socioeconomic factors which determine the economic fragility or robustness of livestock.systems. This will be
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Next Generation Solutions for Sustainable, Inclusive, Resource-efficient and Resilient Cultural Heritage'.

assistant: **Concept**

Culture heritage - tangible and intangible - can be understood as a reservoir of creativity, well-being, identity and knowledge that is useful to overcome present and future challenges. The cultural value attributed to our traditional and historic buildings denotes our identity as communities and individuals, playing an important role both in urban and rural domains. The historic building stock is heterogeneous and consists of buildings from different time periods, constructed in different ways with different materials, and also follows different architectural ideals. This situation implies that there is a need for differentiated renovation strategies and targeted policies  along the heritage built environment’s life cycle that promote energy efficiency, sustainability, inclusiveness and resource efficiency, while preserving cultural heritage value.  The overall vision of INHERIT is to create a systematic methodology, accompanied by leading-edge Information and Communication Technologies (ICTs), such as Internet of Things (IoT), Artificial Intelligence (AI) and (big) data analytics, and associated social/behavioural practices, towards sustainable, inclusive and resource-efficient CH solutions. INHERIT will enable socially innovative and economic viable interventions at different urban levels (buildings, city/neighbourhood), covering all relevant aspects of the heritage-built environment’s life cycle: (1) Design and renovation; (2) Monitoring, operation and management; (3) Preservation and maintenance. The solutions will be tested in 8 cultural heritage sites across EU. In addition, INHERIT will create a capacity building programme addressing heritage operators and stakeholders (including large companies, SMEs, public authorities, research organisations and citizens) to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Building blocks of the molecular universe: A coordinated laboratory and theoretical study of elemental C2X (X=N, O, Si, S) molecules' (RL-ASTROPRO) targeting Horizon 2020.

assistant: **Abstract**

Elemental C2X (X=N,O,Si,S) molecules are fascinating examples of the richness and variety of the carbon chemistry impinging our universe. Not by happenstance, they are ubiquitous in the interstellar medium and known to drive the C-chemitry in its colder and denser parts. With the specific goal of supplying key input data for astronomical observations and astrochemical models, this MC proposal aims at providing spectroscopic and kinetics attributes for C2Xs (X=N,O,Si,S) based on joint laboratory and theoretical studies. Special efforts will be put in the computation and analytic representation of their global potential energy surfaces (PESs). Novel theoretical strategies will be particularly devised in order for the PESs provide spectroscopically accurate information near the equilibrium structures (via rovibrational calculations), while behaving in a physically reasonable manner elsewhere to allow for reaction dynamics studies. The quality of the predicted transition frequencies will be judged and validated with high-resolution laboratory IR experiments. As part of this synergy, individual training in (experimental) spectral analysis and astrochemistry will be pursued by me, thus covering all aspects of lab astrophysics and its link to my existing knowledge on theoretical chemistry; this latter being the main facet transferred to the host university. The advances expected in both theoretical and experimental analysis separately will add up to the methodological improvements made by their in-house interplay, thence allowing the use of astronomical spectra with much higher impact. As a result, it is certain that the new data will trigger astronomical observations of such species. Besides offering a unique opportunity to develop my professional maturity, this MC work plan
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Small-Molecule Drug Conjugates for Targeted Delivery in Tumor Therapy' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Despite the continuing development of new and more efficient treatments, cancer remains the second cause of premature death worldwide. Multi-faceted interdisciplinary research efforts in industry and academia on different aspects of cancer have provided a knowledge basis for the development of novel therapeutic approaches. Paul Ehrlich, Nobel laureate in Physiology of 1908, had the early vision that a compound could be made to selectively target a disease-causing organism or tumor. A toxin for the particular tissue could be delivered by an agent of selectivity. Such an ideal therapeutic agent would be a ""magic bullet"" that only kills the target cells. This ETN initiative with the title Magicbullet::reloaded refers to Ehrlich’s bold idea and builds on the previous experience of the highly successful ETN MAGICBULLET (2015-2018, grant agreement No. 642004). As a consequence of the outstanding results, the ETN Magicbullet::reloaded will expand the field of investigation from peptide-drug conjugates (PDCs) to small molecule-drug conjugates (SMDCs) with a special focus on drugs capable to stimulate tumor immune responses and overcome resistance to immuno-therapy. The consortium has been substantially expanded to perfectly address the needs of the new research direction. The planned ETN will design and synthesize an array of SMDCs (including PDCs), also targeting less investigated tumor antigens, investigate their pharmacokinetic behaviour, their implication on the immune system, as well as their tumor selectivity and antitumor activity. The consortium brings together interdisciplinary expert knowledge in Organic Chemistry, Peptide Chemistry, Medicinal Chemistry, Drug Discovery, Biochemistry, Pharmacology and Cell Biology. This high complementarity is required for the differ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Tools for the genetic improvement of sea bass. Construction and preliminary application of a medium density linkage and synteny map' (BASSMAP) targeting Fifth Framework.

assistant: **Abstract**

BASSMAP will prepare a medium density linkage and synteny map to improve the knowledge on inheritance in sea bass.The aims to reach this goal are:1)The breeding of haploid (mitotic), meiotic gynogenetic and F1 crosses of reference families.2)To provide DNA from the reference families to other mapping projects in an attempt to speed up the acquisition of additional markers and genes on the map.3)The development of a partially characterised Bacterial Artificial Chromosome library for the long-term support of mapping and comparative genomic in this species.4)The development and anchoring of a genetic linkage map using a mixed strategy including dominant (Amplified Fragment Length Polymorphisms) and co-dominant DNA microsatellite markers.5)Development of a synteny map on the basis of Expressed Sequence Tags for comparative mapping.6)A pilot study in an industrial environment to draw the attention of end-users in the field of Quantitative Trait Loci.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Optical Camera Communication For SATellites' to be submitted under Horizon Europe.

assistant: **Abstract**

OCC4SAT aims to develop an enabling communications technology for the space industry, providing a solution to some current needs of the space sector, such as the intra-satellite communication links and the reduction of the dry mass of data transfer cables, connectors, and shielding. The project proposes the integration of Optical Camera Communications (OCC) into the intra-satellite environment providing the flexibility of this technology for enabling new unprecedented flexible design opportunities thanks to the inherent spatial multiplexing capabilities of OCC, its cost efficiency, and the possibility of grasping reflections on the inner walls (and objects) of the satellite to establish NLOS links.OCC4SAT addresses Area 2 of the call. The project will provide two main technology demonstrators (which will be discussed in more detail in the Implementation section): (i) an intra-satellite OCC network simulator that could serve as a tool for speeding up satellite design while providing performance estimates and (ii) a physical demonstrator based on a satellite mock-up able to showcase the flexibility, robustness, and performance provided by the OCC technology.The project's main objectives are a link range of around 1 m suitable for the mini satellites, a data rate above 3 kbps enough for the satellite operation, or a mass below 300 g using lightweight COTS cameras and discrete LED devices, to name a few. OCC4SAT will address several relevant challenges related to both the space and communications fields, such as the limited power supply, weight, space, and clearances in smallsats, or the high spatial multiplexation order of the OCC nodes, the increase of the data rate and the developed of links based on reflections on the payload surfaces, among other.


**Keywords:** Optic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Novel treatment of inflammatory diseases' in the context of a Horizon 2020 call.

assistant: **Objectives**

LipUm has discovered a novel treatment of rheumatoid arthritis (RA) and potentially other inflammatory diseases by a uniquetherapeutic antibody directed towards the Bile Salt-Stimulated Lipase, which has been identified as a key target to block andthereby inhibit the inflammatory process and prevent joint destruction.The global prevalence of RA is 0.3-1%, and it is twice as common among woman than men, and the risk to develop thecondition increases by age. Frequently, other serious diseases are co-occurring with RA and according to the World HealthOrganisation 50% of patients in developed countries are unable to hold a full-time job within ten years after disease onset.The societal economic burden due to the disease is thus enormous, while health economic calculations estimate the cost forpharmaceuticals to less than 20% of the total cost. Still, the drug market value growth between 2014 and 2019 is expected toincrease by 55% to 30 billion USD.The introduction and use of biologicals such as the TNF-alfa inhibitors constituted a major achievement in the treatment, butwith time it has also been concluded that 1/3 of patients are not responding and another 1/3 experience only a transientimprovement. As these biologicals suppress the immune system such drugs should not be combined with otherimmunosuppressants, as it may create adverse health effects. Key opinion leaders have therefore pointed out the need fordrugs that have a complementary therapeutic mechanism.This is the gap that LipUm intends to fill and a tentative strategy is to apply for a orphan drug designation for juvenileidiopathic arthritis that affect children, frequently with extreme disability and poor quality of life. As an orphan drug our uniquebiological more rapidly could contribute to improved treatment o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Single pilOt Line Operations' (SOLO) targeting Horizon Europe.

assistant: **Abstract**

SOLO intends to pave the way for the commercial operations of next generation airliners proposing Single Pilot Operations, which are anticipated within the next decade.To this aim, SOLO encompasses one single Operational solution that will produce a TRL 4 ATM Concept of Single Pilot Operations. This will initiated based on previous works initiated by Airbus and ATR with the support of French partners (DSNA, EUROCONTROL, ENAC) and, as well, be based on the technological bricks developed during those previous R&T activities. In support to Airbus and ATR, the maturation and validation of this concept will be done with the formal cooperation of DFS, ENAIRE/CRIDA, EUROCONTROL, DSNA, NATS and INDRA. Indeed, one major constraint for the TRL 4 concept will be to reduce to the minimum necessary the impacts on ATC tools and procedures.Airline functions and tools will need to be enhanced to prepare and execute Single Pilot Operations, in addition to the major evolutions needed at the cockpit side (not the purpose of SOLO). Several airlines had -on an anonymous way- supported Airbus and ATR for several years. It is planned that a similar way of working will be done during the execution of the project.In the end, the TRL 4 Concept of Operations (instantiated by a comprehensive SPR/INTEROP/OSED) will feed further, more specific R&T activities and as well provide solid basis to various standardization and regulatory bodies such as ICAO, EASA, FAA, CAAC.


**Keywords:** Single Pilot ATC ATM
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Mediation of stem cell identity and aging by proteostasis'.

assistant: **Innovation**

By 2050, the global population over the age of 80 will triple. Thus, research for improving the quality of life at older age can be of enormous benefit for our ever-aging society. To address this challenge we propose an innovative approach based on a combination of stem cell research with genetic experiments in C. elegans. Mechanisms that promote protein homeostasis (proteostasis) slow down aging and decrease the incidence of age-related diseases. Since human embryonic stem cells (hESCs) replicate continuously in the absence of senescence, we hypothesize that they can provide a novel paradigm to study proteostasis and its demise in aging. We have found that hESCs exhibit increased proteasome activity. Moreover, we have uncovered that the proteasome subunit RPN-6 is required for this activity and sufficient to extend healtshpan in C. elegans. However, the mechanisms by which the proteasome regulates hESC function remain unknown. Our first aim is to define how the proteasome regulates not only hESC identity but also aging and the onset of age-related diseases. Moreover, one of the next challenges is to define how other proteostasis pathways impinge upon hESC function. We hypothesize that, in addition to the proteasome, hESCs differentially regulate other subcellular stress response pathways designed to protect them from disequilibrium in the folding and degradation of their proteome. We will perform a comprehensive study of proteostasis of hESCs and mimic this network in somatic cells to alleviate age-related diseases. Finally, we will determine whether loss of proteostasis promotes somatic stem cell (SC) exhaustion, which is one of the most obvious characteristics of the aging process and contributes to tissue degeneration. By using mouse models we will examine whether s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Directing Energy Flow in Semiconducting Carbon Nanotubes for Enhanced Optoelectronics' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Semiconducting Single-Walled Carbon Nanotubes (s-SWCNTs) are a unique class of semiconductor.s-SWCNTs hold significant promise for improving next generation optoelectronics because of their chirality dependent band, stability, conductivity and solution-processability. More importantly, unlike the most common bulk semiconductors, s-SWCNT are intrinsically 1D. That means that, films made of aligned tubes can transport energy along a specified direction, allowing potentially to control energy and exciton flow in previously unprecedented ways. However, even if  films of aligned s-SWCNT have been experimentally demonstrated, directional charge flow has not yet been measured nor has the absorbed light energy been converted into electricity. The main aim of this project is to fabricate thin-film and devices of aligned SWCNT to investigate directional energy flow and its conversion into electrical current, by leveraging ultrafast spectroscopies. This work is driven by three primary goals:1) isolating s-SWCNTs, depositing thin-films and incorporating them into photovoltaic devices; 2) exploiting two-dimensional electronic and photocurrent spectroscopy to examine the energy flow channels and kinetics, and 3) to explore ultrafast free-charge generation with sub-15 fs time resolution to understand how to enhance device performance.This research methodology involves the development of innovative s-SWCNT device architectures, consisting of layered films with controlled bandgap gradients and aligned tubes, in order to optimize exciton and energy directionality and efficiency. Cutting-edge spectroscopic techniques will enable comprehensive mapping of the of energy and exciton dynamics. Thought the integration of expertise from the hosting institutions; this project will contribute sign