RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Control strategies for visceral leishmaniasis (VL) and mucocutaneous leishmaniasis (MCL) in South America: applications of molecular epidemiology.' under Sixth Framework.

assistant: **Concept**

A full and detailed understanding of the transmission cycles and epidemiology of visceral leishmaniasis (VL) and mucocutaneous leishmaniasis (MCL) is necessary to develop disease control and surveillance. Molecular epidemiology and population genetics can resolve the diversity and structure of Leishmania populations, for ex. the intricate relationships between clinical forms of human infection and mammal reservoirs. Research will involve comparative investigations between endemic areas for VL and MCL in Par aguay, Peru, Brazil and Venezuela and will strengthen local capacities for research and for Latin Am-European collaborations. The technical aim is to develop a full range of microsatellite markers and multi-locus sequencing typing (MLST) of housekeeping ge nes for the Leishmania braziliensis complex and for L guyanensis. We will also establish in South America the procedures for microsatellite and MLST analysis for L infantum, which have been developed and proven as epidemiological tools by a European networ k. The practical aims are to encourage the application of these and other molecular epidemiological methods in S. America for 1. elucidating parasite-vector-host relationships 2. assessing the epidemiological impact of VL-HIV co-infection (Brazil) 3. asses sing the epidemiological importance of recombinant Leishmania genotypes and 4. assessing the spread of resistance against 1st line treatment (SbV). In addition we will compare genotypes of a) Leishmania isolated from diverse clinical cases of leishmaniasis and b) drug susceptible and drug-resistant strains. The project will be undertaken in the context of an investigation of present understanding and intervention strategies among health professionals, defining how best to introduce project outputs into impr ove
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Improved high speed steel cutting tools for higher machining productivity and reduced tool wear' (1994-1998).

assistant: **Concept**

The engineering industry is increasingly required to machine higher performance alloys designed for high temperature, abrasion resistant, high strength and corrosion resistant applications. Furthermore, the in-house workshop capacity of large manufacturing industries such as automotive and aerospace is being reduced, and globally the outsourcing of key machining operations is increasing. This presents a significant opportunity for the subcontract machining sector, which in the main consists of SMEs. However, these high performance alloys are considerably more diffcult to machine than conventional alloys, and for SMEs to take advantage of this opportunity, they must make significant improvements in their productivity. This can be achieved by utilising cutting tools in advanced materials but this can only be done in conjunction with large investments in more rigid machine tools. The objective of this proposal is to increase the hot hardness capability and wear resistance of the inherently tougher high speed steels using advanced powder metallurgy techniques, thus allowing SMEs to address these opportunities using their existing machine tools.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Intelligent URBAn eNergy tool', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

iURBAN proposes to develop and validate a software platform that will integrate different ICT energy management systems (H/W and S/W) in two European cities.This intelligent URBAn eNergy tool will provide useful data to a novel decision support system that will make available the necessary parameters for the generation and further operation of new business models. These business models will contribute at a global level to efficiently manage and distribute the energy produced and consumed at a local level (city or neighbourhood), incorporating behavioural aspects of the users into the software platform and in general prosumers (entity that consumes and produces energy).To create such a tool, iURBAN will develop a SMART urban Decision Support System (smartDSS), i.e. a customized energy management and control platform in the framework of a city. The smartDSS will allow for scalability and incorporate a two-level Decision Support System: Local Decision Support System (LDSS). It will engage consumers and prosumers by capturing near real-time data related to their energy consumption, as well as production from their installed Distributed Energy Resources (DER), and displaying it on a user-friendly interface via smart phones, tablets, PCs, etc. Centralized Decision Support System (CDSS). It will aggregate data from all LDSSs to provide city-level decision support to authorities and energy service providers.  The CDSS will generate a number of parameters, including city-wide energy production and consumption forecasts.A methodology for the validation and evaluation of the impacts resulting from the deployment of the iURBAN smartDSS will be developed. This methodology will be based on widely used IPMVP protocols and will include a Social Cost-Benefit Analysis using social and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Enhancement of an advanced clinical trial recruitment platform for Europe to ensure maximum intake of eligible consenting patients for participation' (CliniTrial).

assistant: **Innovation**

Many patients can’t effectively be treated with the standard of care today. They suffer from their diseases that can’t be managed or cured. Newly developed therapies represent their only hope.Unfortunately, it takes ever more time and money to bring innovative therapies to market. A major challenge in clinical development is finding the right patients to participate in clinical trials. The problem is that patients lack access to trials.The online platform viomedo supports patients with finding the right clinical trial for them, while helping the organizations that run trials, such as pharmaceutical companies, recruit patients more efficiently. The disruptive solution provides access to over 2.000 up-to-date clinical trials that are recruiting patients in Germany. Patients, care givers or doctors can easily search for a trial by disease, confirm their eligibility and contact the investigator. Patients want to be increasingly involved in deciding which therapy to choose. 75% of them are interested in learning about clinical trial opportunities. Most turn mainly to the internet for health-related information. However, a patient-centric online platform for clinical trials is missing. Viomedo empowers patients by providing this platform.Important milestones – such as the development of a public beta version of the platform, collaboration with leading patient advocacy groups, acquisition of six large pilots with pharmaceutical companies – have been reached. The goal of phase 1 is to complete the pilot projects and develop an EU-wide rollout strategy. After the business case is ready and validated, viomedo will be rolled out to major European markets in phase 2. Once viomedo is rolled out to all European patients, it will help more patients benefit from the research earlier. I
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Dissemination, implementation and evaluation of educational materials on biotechnology' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

The European Initiative for Biotechnology Education (EIBE) seeks to promote skills, enhance understanding and facilitate public debate through improved biotechnology education in schools and colleges throughout the EU. Founded in 1991, EIBE has become ar active European multidisciplinary network of experts in biotechnology education drawn from 20 centres in 12 countries. In the proposed new Concerted Action 28 centres from 17 countries will be involved. In the past EIBE activities have been centred around the development of EIBE units for in-service teacher training (INSET) and initial teacher training using scientific anc technological subjects in association with relevant economic and societal issues, anc a range of teaching media and materials. The main feature of the proposed new Concerted Action will be dissemination, implementation and evaluation of existing EIBE materials and involvement of a wider target audience in a broader range of actions than hitherto possible. Dissemination activities to be addressed include: extending procedures for wider distribution of EIBE material, e.g. improving accessibility of the EIBE web site, improving ways of duplication and distribution of an EIBE CD ROM; extending co-operation with other organisations through wider networking; broadening the national representation among EIBE membership, especially with countries from Southern and Eastern Europe; greater involvement with teachers of non-science based subjects (e.g. to expand the range of school subjects and disciplines which are exposed to biotechnology by adaptation of EIBE materials for the humanities, languages and drama); to broaden both the present target audience (science teachers) and other groups (especially nonscience teachers, colleges involved in teacher training,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'SUstainable Network for Japan-Europe aerospace research and Technology cooperation II' (2014-2020) under Horizon 2020.

assistant: **Objectives**

SUNJET II proposal responds to the H2020-MG-2014 Topic 1.8 International Cooperation in Aeronautics of the work programme. Its main objectives are:• Recommendations and guidance for future EU-Japan cooperation in the field of aviationBuilding on the SUNJET project, SUNJET II will produce consolidated roadmaps in the fields of Aircraft, Systems and Equipment, with the support of R&T institutions, Academics and Clusters. The roadmaps’ consistency as well as their level of granularity will be checked, key topics for future EU-Japan R&T cooperation in the field of aviation will be selected, with an assessment of the funding and time required, and concrete recommendations for future EU-Japan Calls will be produced, taking into consideration the EU and Japanese R&T mechanisms. A Guidance Desk will make available relevant guidance material, including recommendations and best practices to a wide community interested in building a joint research project between Europe and Japan in the future.• Promote communication and networking between EU and Japan in the field of aviationA Forum of exchanges between European and Japanese stakeholders will be created. It will be comprised of four physical meeting sessions in Europe and in Japan. A virtual platform will also be set up to maintain communication and develop new contacts remotely between the meetings. Furthermore, a collaboration (web based) platform will be created, designed to host social and semantic functionalities in order to boost the communication between European and Japanese stakeholders. Ensuring that the interested stakeholders will continue benefiting from the services and tools developed by SUNJET II even after the end of the project, the collaborative platform as well as the technical database connecting all roadmaps
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Bioenergetic Remodeling in the Pathophysiology and Treatment of Non-Alcoholic Fatty Liver Disease'.

assistant: **Concept**

FOIE GRAS provides innovative training for 13 early stage researchers (ESRs) to answer two critical and unanswered questions: a) Is hepatic bioenergetic remodelling involved in NAFLD pathogenesis, and target for stratification or therapeutic/lifestyle interventions? and b) Is the disruption of the gut-liver axis involved in NAFLD progression? In Western Societies, there has been a recent surge of non-alcoholic fatty liver disease (NAFLD).  Its progression to nonalcoholic steatohepatitis (NASH) is a leading risk factor for development of Type 2 diabetes, cirrhosis, and hepatocellular carcinoma. FOIE GRAS is first in supporting a cohesive and synergistic intersection of complementary and interdisciplinary training skills from academic and non-academic partners. FOIE GRAS combines strong scientific expertise with integrated and complementary training in translational research, clinical practice, technology commercialization, and public outreach, the combination of which in targeting NAFLD is lacking in the EU. Industrial partners CETICS, Mediagnost and Seahorse Biosciences provide experience on technology commercialization alongside scientific contributions while the affiliated patient organization will contribute with important training in societal awareness topics.  ESRs training will utilize network-wide workshops and secondments to foster translation of basic research to clinical applications and SME creation. This diverse yet integrated skill set enhances the employment prospects of the trained researchers in both academic and non-academic sectors. Researchers will be endowed with excellent basic scientific knowledge and timely technology transfer know-how for developing novel therapeutic approaches for reversing the burden of NAFLD, thereby advancing both health and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Innovative Multi-disciPlinary European Research training netwOrk on VolcanoEs' (IMPROVE).

assistant: **Innovation**

Based on previous and current international projects and initiatives, IMPROVE aims at training the new generation of volcano scientists who manage inter-disciplinary understanding and knowledge, pursue innovation, and cooperate in an inter-sectorial, Open Science environment. IMPROVE ESRs are trained to grow as independent scientists with broad overviews and top level expertise, able to convert their knowledge, ideas and skills into scientific advance as well as economic and social benefits. The consortium involves nine academic Beneficiaries, and three Partners constituted by one Energy State Company and two technology-developing SMEs. The underlying research aims at the definition of the underground structure and dynamics of volcanic and geothermal systems, with innovative objectives expected to impact significantly volcano science as well as science-industry relationships; and involves exploration and monitoring methods, disciplines like geology, geophysics, geochemistry, engineering, informatics, and theoretical and experimental approaches. The program includes two multi-disciplinary Field Experiments, four Network Schools, five Specialized Short Courses, three ESRs’ Workshops, one Network Workshop on science-business relationships, nine Digital Training Modules, and a Final Conference. Multidisciplinary data will be managed through a Data management Plan, and organized in a database fully available to the consortium and, after project closure, accessible by the broadest scientific community. ESRs’ training-through-research develops under multi-disciplinary team work and multiple tutorships, and includes as major training elements a variety of transferable and soft skills aimed at growing a generation of young scientists who are highly attractive for science as well
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Zouj: Dynamic Jewish-Muslim Interaction in Popular Maghribi Comedic Performance Culture since the 1920s' (DJMI), addressing dissemination and exploitation.

assistant: **Impact**

DJMI will provide the first systematic study into the dynamics of Muslim-Jewish interactions in popular comedic performance culture from the 1920s in the Maghrib and France, until the present day. The project’s hook is the word Zouj because of its shared meaning in Arabic and Hebrew: a couple, or two. While there is recognition that such ‘Mediterranean culture’ existed, there has been all too little analysis of how it functioned in the past, what its current state is, and what the implications of such change are. In its venture to explore the dynamics of these dialogical interactions through popular culture, DJMI will begin by investigating the satirical sketches of early popular comedic theatrical production in Morocco and Algeria as the crucible for the North African performing arts scene to come. These sketches were sui generis and cross-genre, adapting elements of local halqa—circle-based qu’ranic recitation—commedia del’arte-style street theatre, local musics, and the telling of folk tales and everyday-vignettes in local Arabic in the public square. DJMI traces the dynamics of Jewish-Muslim interactions through the production and texts of these sketches to Maghribi chaâbi (popular) music, and on to stand-up comedy in the present day connecting to a renewal of interest in Muslim-Jewish interactions among new generations across northern Africa in reception to a recent wave of literature, film, and music that seeks to depict or reimagine these interactions and relations. DJMI thus connects the historical to the anthropological proto-nostalgia of this reception to focus on the debates and interconnections that this renewal of interest produces and where this emanates from. These perspectives and their historical basis are of the uttermost importance in light of the per
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Role of Id4 in the adult subventricular zone of normal and injured brain' to be submitted under Horizon 2020.

assistant: **Abstract**

The aim of this proposal is to propose a scientific research project and a training plan for Dr. Brenda Rocamonde. The scientific research project aims to understand the function of the transcriptional regulator Id4 in the adult subventricular zone (SVZ) under physiological and pathological conditions. The SVZ is one of the largest neurogenic niches of the adult brain, generating new neurons from neural stem and progenitor cells, throughout adulthood. This region is activated after brain injury, such as ischemic stroke. Inhibitor of DNA binding 4 (Id4) is a transcriptional regulator that acts by antagonizing transcription factors. In the developing brain, Id4 is required for neural progenitor cell proliferation and differentiation. However, the function of Id4 in the adult SVZ has not been reported. We have observed that Id4 is expressed in neural stem cells and cells of the neuronal lineage in the adult SVZ. We propose to use in vivo approaches to (i) determine Id4 function in the SVZ by loss and gain of function approaches, and (ii) evaluate its role in the response of the SVZ to ischemic stroke, a major cause of disability in Europe. This project, undertaken in an international research center and carried out by a talented fellow will provide insights into the mechanisms underlying the regulation of adult neurogenesis in the normal and injured brain. In addition, we are proposing a career development plan for Dr. Rocamonde that includes training on scientific and transferable skills. This plan will widen Dr. Rocamonde’s competences and provide her with the tools to become a leading independent researcher.