RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Double Dynamics for design of new responsive polymer networks and gels' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Polymeric gels and networks are ubiquitous in daily life (foodstuff, cosmetics) and high-added value applications (tissue engineering, adhesives, coating, drug release, portable batteries, additive manufacturing). They can be either permanent (covalently crosslinked) and resist flow, or physical (reversible) and easy to process while creeping at long times. The grand challenge is to efficiently combine and control within the same material, distinct features of these two classes of networks, such as large mechanical strength, deformability, swelling and self-healing, in order to create multiply responsive materials for new applications.The objective of DoDyNet is to develop a research roadmap that enhances our understanding of the synergistic effects arising by combining distinct dynamic modes within a polymeric network. These ‘Double Dynamics Networks’ (DDNs) are characterized by a multi-scale viscoelastic response that can be tuned via molar mass, fraction of component and dynamics of (transient or exchangeable) bonds. This will enable us to selectively tailor their macroscopic properties at molecular level.Based on this concept, the integrated research program involves (1) novel synthesis of different DDNs; (2) detailed analysis of structure; (3) rheology and dynamics; (4) modeling and simulations; and (5) mechanical properties relevant to applications. The ESRs will benefit from the close inter-connection among these complementary tasks with the goal to obtain criteria for designing and developing new industrial DDN systems and optimizing existing materials.DoDyNet is a highly interdisciplinary and inter-sectorial project, the groups involved are world-leaders in their fields, and the tasks strategically designed to ensure strong synergies. It offers young researcher
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The impact of collisional dark matter in galaxy formation: Time for a paradigm shift?' to be submitted under Seventh Framework.

assistant: **Abstract**

Discovering the nature of dark matter is one of the most significant challenges for modern astrophysics. The favourite theoretical model, the Cold Dark Matter (CDM) paradigm, assumes that dark matter is made of collisionless particles acting on galactic scales purely through gravitational interactions.Despite that the CDM model is remarkably successful in reproducing the large-scale structure of the Universe, it seems to be in tension with observations of low-mass galaxies. The internal dynamics of these galaxies is governed by the dominant dark matter haloes they live in, and would be expected to show the presence of dark matter density cusps, an imprint of the collisionless nature of CDM, instead, they seem to be consistent with the presence of large central dark matter cores.Although the solution to this challenge might lie in our still incomplete understanding of the physics of galaxy formation, it is equally likely that these observations contradict the fundamental hypotheses of the CDM model, and might give us a clue about the underlying dark matter nature. This proposal aims at studying the formation and evolution of galaxies in the context of Self-Interacting Dark Matter (SIDM) where dark matter is self-collisional. This objective will be pursued by pioneering cosmological simulations that couple the collisional behaviour of dark matter to the physics of gas cooling, star formation and supernova feedback to simulate the formation of realistic low-mass galaxies.The completion of this proposal will possibly establish a paradigm shift in dark matter physics and open a new horizon in galaxy formation where dark matter microphysics plays a primary role.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Development of a new technique of mould cleaning in agrofood industry and reusing' to be submitted under Fifth Framework.

assistant: **Abstract**

The agro food industry that works in sweets and confectionery sector has many processes that use great amounts of water. One of the most significant processes, from the wastewater-produced point of view, is the mould cleaning, either of chocolate or of other products. This problematic implies an important economical cost to the companies, both because the high volume of water consumed and because the amount of organic material waste. The main objective of this project is to minimise the volume and pollutant load of the wastewater from mould cleaning processes in the agro food industry, specifically in sweets and confectionery sector. This problem will be attacked by different fronts:- moulds of new materials and improved properties for turning out leaving less food residues- process parameters optimised- pre-cleaning treatment without water to minimise the stuck residues using new technologies as vibration, nitrogen and others- water-save cleaning technologies that produce less wastewater- recovering and reusing of wasted product The expected results will be:- Reduction in water consumption- Reduction in wastewater discharges- Valorisation of wasted product
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Unveiling the signature of transposable elements-derived transcripts – the transposcriptome – as a biomarker in human acute myeloid leukemia' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Acute myeloid leukemia (AML) is the most common of the acute leukemias among adults. Relapsed AML patients are frequent but difficult to treat since effective therapies are limited. This mediocre outcome can be partially explained by the presence of leukemia stem cells (LSC) that maintain an aberrant hematopoietic process. LSC in AML were traditionally thought to be solely CD34+CD38- cells. However, recent studies demonstrated the presence of LSC in cell fractions thought to be non-tumorigenic. Finding an LSC-specific signature would be decisive for a better categorization of patients and LSC exclusive targeting.This project considers the signature of transposable elements (TEs) as an ideal tool for the identification of LSC. TEs, with important roles in gene regulation, are linked to the reprogramming process to pluripotency and they are associated with tumorigenesis. Since they contribute up to two thirds of the human genome, TEs expression provides much denser coverage of chromosomes than gene-derived transcriptome. TEs signature in cancer has so far been largely unexplored per lack of proper technologies. The advent of high-throughput sequencing and the development of TE-directed analytical pipelines allow now the accomplishment of this project.The present proposal includes a comprehensive characterization of TEs transcriptome in normal and malignant hematopoietic precursors. An expected result is the achievement of a better subclassification of AML samples on the basis of their TEs expression homology to normal progenitors. The project will investigate the existence of TE-derived oncoproteins exclusive for LSC that could be immunotherapeutically targeted.This proposal has impact on the excellence of European science since it will create new collaborations and netwo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Alcohol consumption and alcohol problems among women in european countries'.

assistant: **Concept**

The proposed BIOMED 2 concerted action, Alcohol Consumption and Alcohol Problems among Women in European Countries" will examine the drinking patterns and problems of women in eight European countries. This will be done by comparing alcohol consumption and alcohol problem rates within and between countries and between men and women and among women. In addition, an important methodological component of the proposed concerted action is to make recommendations for much needed standardised measures of alcohol consumption and alcohol problems for use in European alcohol epidemiological research. The proposed project involves the collaboration of alcohol epidemiologists from eight European countries, the Czech Republic, Finland, Germany, Italy, the Netherlands, Scotland (United Kingdom), Sweden, and Switzerland, and will coordinate national efforts on an inter-European level so that trends and patterns within countries may be compared with others and thus may be more readily usable and accessible for European Union policy purposes. The proposed concerted action, "Alcohol Consumption and Alcohol Problems among Women in European Countries" has the following measurable objectives: (1) To standardise drinking measures. (la) With data sets on alcohol consumption which have already been collected by the partner countries, the first objective is to develop standardised units to compare alcohol consumption and alcohol problems across European countries. (lb) Recommendations for standard measures and approaches for future measurement of alcohol consumption and alcohol problems Europe-wide will be developed. (2) To investigate differences in drinking patterns within and between countrie This will be done looking at differences between men and women, and among women. (2a) With available
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Improved Microstructure Measurement Technologies for Marine Surface Flux Studies' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Marine near surface fluxes play a key role in many physical, chemical and biological processes of the surface boundary layer and in this way affect climate and environment In order to establish a meaningful interpretation of air- and spaceborne remotely sensed observations it is essential to deter ine the transfer function linking the subsurface processesto their fingerprint at the surface. An accurate knowledge of near surface small-scale processes requires reliable measurements at the smallest spatial scales. Currently, no suitable sensors and systems are commercially available to carry out these measureoents with the necessary efficiency and precision. The general aim of MITEC i8 to design, develop and build an advanced, efficient, integrated measurement and data handling system and to demonstrate that it is capable of obtaining reliable, high-accuracy information on near surface flux processes in marine waters. In order to achieve this goal within the framework of MITEC the following activities are planned: - Development, adaptation and assessment of methodologies for performingthe near surface microstructure measurements and to evaluate the data. - Development and construction of a free rising system to measure the nearsurface microstructure of density and current fields with a resolutionin the millimetre-range, and to measure bio-aptical properties. The dataacquisition and basic evaluation software will be integFated within thesystem. - Laboratory and field measurements as well as application studies toassess the performance of the developed system and to demonstrate itsapplication potential. The final deliverable will be a complete end-to-end system for the assessment of important physical and biological parameters in the surface boundary layer, from gathering th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Deployable Decision-Making: Embracing Semantics for Robotic Safety in Everyday Scenarios'.

assistant: **Objectives**

Recent breakthroughs in machine learning have opened up opportunities for robots to build a semantic understanding of their operating environment and interact with humans in more natural ways. While machine learning has unlocked new potentials for robot autonomy, as robots venture into the real world, physical interactions with the surrounding environment pose additional challenges. One typical challenge in practical applications is providing safety guarantees in robot decision-making. Much of the safe robot decision-making literature today focuses on explicit safety constraints defined in the robot state and input space. However, in practical applications, robots are often required to infer semantics-grounded safe actions from perception input. While recent machine learning techniques are increasingly capable of distilling semantic information from perception, translating the semantic understanding to explicit safety constraints is non-trivial. In this proposed project, we aim to close the perception-action loop and develop mathematical foundations and algorithmic tools that enable robots to make intelligent and semantically safe decisions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Silicon Carbide Nanowires for Electronic and biosensing applications' under Horizon 2020.

assistant: **Concept**

SiC nanowires (NWs) combine the properties of 1D materials with that of SiC and devices based on SiC NWs would present concrete advantages. The main objective of the project is to develop the technology of SiC nanowire field effect transistors (NWFETs) and demonstrate devices suitable for two areas of application:1) More Moore: Logic applications. SiC NWFETs have the potential of high temperature operation and eventually of efficient power dissipation and thus they can address main issues in semiconductor device scaling.2) More than Moore: Biosensor applications. SiC exhibits superior to Si chemical stability and biocompatibility and SiC NWFET-based biosensors can thus, exhibit challenging performances.Top-down technology approach (lithography and plasma etching) will employed to obtain, suitable material quality (residual doping lower than 1E17 cm-3, same carrier mobility as bulk material and if possible, in-situ doping for channel and contact regions).The targeted performance of the SiC NWFETs is 200ºC operation, an Ion/Ioff ratio above 1E6, a subthreshold swing less than 200mV/decade and an electron channel mobility above 200 cm2V-1s-1. These electrical characteristics address the needs of logic applications while for biosensor applications are largely enough and can be relaxed. The biosensing operation of SiC NWFETs will be shown by detecting different substances (DNA, heavy ions, phenyl groups…). Towards this aim, a large part of the work will be devoted to the study of the relevant functionalization ways for SiC NW surfaces and stability of these surfaces to various aqueous solutions.The main research work will be conducted in INPG while industrialization issues will be investigated in partner organization (CEA-LETI).The fellowship will enhance the professional ma
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'A new cryoprotectant formulation for the next generation of high throughput screening toxicology tests' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

All pharmaceutical, chemical and cosmetic products have to undergo rigorous toxicity testing before going to market. In the past, this was often done through testing with animals, but this approach has been in rapid decline. The alternative is testing of products for toxicity against mammalian cells in multi-well plates. This technique is very important in the pharmaceutical industry where early detection of drug toxicity can reduce the cost of bringing drugs to market. Testing against hepatocytes (liver cells) is critically important, but these cells are difficult to cryopreserve in multi-well plates. At present they have to be shipped globally in a fresh format, presenting major logistical challenges, and then used within days, often with less than ideal results in terms of cell uniformity and test reproducibility.In CryoProtect, I will develop a means of cryopreserving cells within multi-well plates allowing them be shipped to laboratories around the world and thawed only when they are needed. In the absence of ice nucleants, aqueous cell suspensions can supercool well below the ice melting point which often results in cell death. I have already pioneered the use of feldspar as an ice nucleant in cryopreservation. However, feldspar alone is not enough to cryopreserve cells in multi-well plates. In this PoC application I propose to build on a discovery related to our work on ice nucleation by sea spray aerosol, published in Nature. We can substantially improve the ice nucleating ability of feldspar by adding ammonium ions to the solution in which cells are suspended prior to freezing (this solution is called the cryoprotectant solution) leading to enhanced survival rates of hepatocytes. This PoC grant is needed in order to optimise the composition of the new cryoprote
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The Ecology of Crusading: The Environmental Impact of Conquest, Colonisation and Religious Conversion in the Medieval Baltic' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The crusades waged against pagans in the Baltic region from the late-12th century AD proved far more successful than those fought in the Middle East. They had a significant impact on the region   characterised as a cultural frontier which came to be dominated by crusading institutions into the 16th century   and are fundamental to understanding the development and consolidation of a European society, united under Christianity. Recent pilot projects directed by Pluskowski, focusing on castle sites in Poland and Estonia, have suggested the crusading period coincides with an 'ecological watershed' in the exploitation of plant and animal resources, representing a significant human impact on the environment in this region. This project builds on these initial findings, addressing a fundamental gap in our understanding of the process of Europeanisation in the medieval Baltic. It will investigate the extent to which the crusading movement in this frontier region represented a force of ecological transformation. This will be assessed by tracking changes in local environments   the exploitation of animals, plants and landscapes   around castles built by the Teutonic Order, an institution which embodied the crusading movement. An initial survey will evaluate six castles in north Poland, Estonia and Latvia. Following this, two sites will be targeted with a systematic sampling strategy aimed at recovering material culture and a high density of plant and animal remains associated with occupation sequences. Environmental data will also be extracted from the hinterlands of these sites. This will be integrated with written sources in order to assess the full extent of the ecological transformations resulting from the introduction of these European structures into this frontier region.