RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Solidification of Peritectic Alloys: a Computational Exploration' to be submitted under Horizon Europe.

assistant: **Abstract**

Advanced metallic alloys produced from recycled scrap can significantly reduce emissions, waste, and energy consumption. However, technological alloys with extreme chemical complexities impede the development of high-performance sustainable alloys. Microstructure-oriented alloy design opens promising avenues to guide the development of sustainable (i.e. leaner and less complex) alloys via tailoring the desired microstructure during solidification. Yet, while the development of dendritic and eutectic microstructures is relatively well understood, the comprehension of growth mechanisms of peritectic solidification (common to a broad range of alloy families) remains incomplete. The SPACE project will develop a quantitative phase-field model to investigate the emergence of complex growth patterns during peritectic solidification. To do so, we will (i) develop a quantitative multi-phase and multi-component nondiagonal phase field (MP-MC-NPF) model based on Onsager's relation, (ii) validate the model against sharp interface calculations and experimental observations, (iii) explore three-dimensional peritectic growth mechanisms at experimentally- relevant length and time scales (via GPU code acceleration), and (iv) study the effect of minor element addition (e.g. impurities from recycling) on microstructure growth and selection. We will focus, primarily, on binary Fe-Ni and ternary Fe-Ni-X alloys with high impact potential. The resulting MP-MC-NPF framework will shed light on the fundamental mechanisms of complex growth patterns and morphology transitions during peritectic solidification (for the first time in three dimensions and transient conditions) and thus contribute to the transition toward microstructure-oriented design of impurity-tolerant sustainable alloys.


**Keywo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The genetic basis for glial differentiation in the developing zebrafish retina.' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

Glia far out number neurons in the brain and their defects are now known to be associated with many neurological diseases. Glial specification and physiological function are very well studied however, remarkably little is known about they way in which glia are positioned or shaped in order to perform their critical support functions.  The goal of the present study is to broaden the field of glial development by using new techniques to ask previously unattainable questions.  This central goal of this research project is carried out through an in-depth morphological, genetic and transcritpomic analyses of differentiating Müller Glia in the Zebrafish (Danio rerio) eye.  Results from these studies will provide and the first extensive profiling of a differentiating glial population.  Furthermore, the extensive data that will be generated in this proposal will provide a basis for many future studies on glial biology for both in the host laboratory and  for the experienced researcher during his career development. Ultimately, these and future studies will provide a foundation for identifying the molecular networks that underlie glial patterning in the brain that will no doubt be informative in the study of glial related neurological disease.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Development of human primordial germ cells towards the onset of sperm and egg differentiation in a novel model culture system' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Human primordial germ cells (hPGCs), the precursors of sperm and eggs, originate in early pre-gastrulation post-implantation embryos (~wk2). Thereafter, hPGCs undergo wide epigenetic reprogramming during their migration to the primitive gonads (~wk3–7). While technical and ethical constraints preclude direct studies on early human embryos, recent development of 2D models using human pluripotent stem cells (hPSC), which simulate early post-implantation development, have been used to investigate the specification of hPGC-like cells (PGCLCs) equivalent to wk2 hPGCs. These models however cannot support extended maturation of hPGCLCs beyond this early stage. Here, we propose a novel 3D in vitro system to advance development of hPGCLCs up to the onset of gametogenesis, extending our knowledge of the key events of early human germline development. This project will benefit from the cell culture capabilities of the three-layer gradient system (3-LGS), a 3D cell culture method that I invented during my PhD, combined with the expertise of Prof. Surani’s lab in generating hPGCLCs from hPSCs. The 3-LGS will be used to create gonadal organoids from human fetal primary cells, which we call “germinoids”, in order to support further development of hPGCLCs beyond the in vivo equivalent 2-wk stage. During this innovative project, we intend to achieve our objectives to create firstly, the novel co-culture germinoid conditions, and secondly to use the model to advance hPGCLCs differentiation. The generation and characterization of germinoids will be conducted in a collaborative team of experienced scientists and students, under renowned supervision and within a supportive and available work environment and infrastructure. This project will extend my expertise and contribute to the host’s w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Vibrational intensity processing by full-field laser multi-pulse technique' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

In many industrial sectors there is a strong demand for measuring, modelling and optimising noise and vibration properties of parts and products at the prototype stage, under controlled excitation or in operating conditions. The aim of the VIP project is to develop an efficient and easy to use tool to meet these requirements. New equipment and evaluation tools for holographic recordings will provide new kinds of integral information about the vibration behaviour of structures: * full field amplitude and phase of vibrations under operating conditions; * eigenmodes of vibration; * vibrational intensity vector maps and its divergence, giving flow, sources, and sinks of vibrational energy; * acoustic radiation and stress fields in the structure. The objective of the project is to give complete and global information, as above, for any kind of object and geometry under arbitrary excitation conditions. To reach this goal, 3 D cineholographic and pulsed TV holographic methods will be developed, associated with new types of data processing that allow direct links to existing CAD and FEM software. FEM models will be updated based on the new, integral experimental recording. They can then be used to predict and optimise noise and vibration of structures and their modifications, thus leading to speedy prototype design cycles and reduced time tomarket. Major innovations of this project include the on site visualisation of vibroacoustic properties of arbitrary structures, geometries, and deflections, and the integration of these data into new and existing modelling tools.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Understanding the Consequences of Major Health Crises for Education: Learning from the COVID-19 Pandemic (LEARN)' in the context of a Horizon Europe call.

assistant: **Objectives**

Health crises, natural disasters, and violent conflicts pose global threats to children’s educational development. The frequency and severity of such disruptive events is intensifying due to climate change and the growing instability of the global security architecture. Yet, we lack a systematic understanding of how major disruptive events affect children’s educational development, largely because such events tend to also disrupt the collection of high-quality data on children’s education.Due to the global scale of the COVID-19 pandemic and extensive data collection efforts as it unfolded, the COVID-19 pandemic offers a unique opportunity to advance our understanding of the consequences of major health crises for children’s educational development. LEARN will leverage this opportunity to reveal the principal pathways through which the pandemic has affected the educational development of children in different world regions, as well as the key factors that reduce or exacerbate its adverse consequences.LEARN will generate and apply high-quality, cross-national data and advanced quantitative and meta-analytical techniques to achieve five core objectives:(1) Trace children’s recovery of COVID-19 learning deficits using a living meta-dataset and online tracker(2) Assess COVID-19 effects on children’s early-life trajectories(3) Map the processes through which the pandemic affected children’s educational development(4) Reveal the factors that reduce or exacerbate COVID-19 effects(5) Identify the most effective remedial education interventions to promote children’s learning recoveryThis ambitious and innovative research programme will substantially advance our understanding of how major health crises affect children’s educational development, generate several new data resources,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'AALIANCE2 - Next Generation European Ambient Assisted Living Innovation Alliance', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Subject of the Coordination Action AALIANCE2 will be Ambient Assisted Living (AAL) solutions based on advanced ICT technologies for ageing and wellbeing of older persons in Europe. AALIANCE2 will built upon the successful work and the wide network already established in the AALIANCE Innovation platform (2008-2010).AALIANCE2 willTransform the existing AALIANCE Community in a long-term sustainable network- to create the central entity for all AAL-related issues and stakeholder in Europe- to form an European Technology Platform focusing not solely on technology but on integrated solutions for a societal challenge- to provide a central node for global interaction<br/>Find solutions for major challenges in AAL which consist of- coordinating the various activities of European industry and research institutions in the field of Ambient Assisted Living by building consenus upon research priorities in a AAL roadmap and Strategic Research Agenda for the upcoming decades- standardisation requirements in the field of ICT and Wellbeing (incl. care and healthcare standards)- providing recommendations for a overcoming market barriers and effective regulations in AAL markets- investigating the the current state-of-the-art and market developments in AAL in North America and Asia<br/>Support the implementation of coherent strategies of the public and private sector.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Leading Utility-scale RES Market Expansion towards Next-generation Energy Systems' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Although decentralized and utility-scale renewable energy sources have grown, the EU must speed up their deployment to meet decarbonisation targets. Outdated grid infrastructure, limited system flexibility, complex regulatory frameworks, and rising NIMBY attitudes hinder the full market integration of these plants, affecting their business models and service monetization. Addressing these issues is essential for both facilitating the deploying of new utility-scale RES plants and maintaining previously existing ones and its viability.To achieve this, LUMENS will implement a comprehensive strategy built on three key pillars: (1) Establishing a multi-actor engagement framework to ensure a strong stakeholder dialogue and capacity building, providing the project with valuable feedback from the sector. (2) Creating a dynamic repository of knowledge transfer materials (KTM), including success stories and recommendations based on a portfolio of cases that will be studied throughout the development of LUMENS, as well as an open-source toolkit composed by analytical and decision-support tools that will aid in a variety of aspects, such as location, sizing, hybridization or market performance prediction of a RES plant. (3) Executing a continuous knowledge transfer strategy that promotes direct interaction with key international market players. With a consortium of nine partners from seven EU countries, including market operators, power system operators, RES promoters, and multidisciplinary research experts, LUMENS is well backed up to develop actionable insights for optimizing key factors including the planning, location, operation, and monetization of utility-scale RES plants among others. Ultimately, LUMENS seeks to enhance the competitiveness of RES plants in the EU energy mark
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'The Cog in the Ratchet: Illuminating the Cognitive Mechanisms Generating Human Cumulative Culture', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

In human populations, skills and knowledge accumulate over generations, giving rise to behaviours and technologies far more complex than any single individual could achieve alone. This ratchet-like property of human culture appears absent in nonhuman species, as socially transmitted behaviours in animal populations are generally no more complex than those that can be acquired by trial and error. Scientists from a wide range of disciplines have offered high-profile speculative theories about the underlying differences that might be responsible for this striking evolutionary discontinuity, but adequate empirical evidence is still lacking. In the RATCHETCOG project, Dr Caldwell and her team will, for the first time, implement a comprehensive systematic investigation into cumulative cultural evolution, using an experimental method that offers sufficient flexibility to generate valid comparisons across three critical research domains: species differences across the primate family tree; age differences over human development; and learning condition differences in groups of adult human participants. The methods devised for the project will make it possible to both measure and manipulate the complexity of the behaviours learned, thus offering a tool for analysing the extent of ratcheting under different conditions and across different populations. Each of the three research strands provides a vital source of evidence. Studies of nonhuman primates will reveal the limits on learning in these species, and studies with children will provide key opportunities to determine which cognitive abilities predict the development of capacities for cumulative culture. Finally, comparing different learning conditions in groups of adults is critical, as these experiments will allow clear causal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Lightweight In-situ Tracer Experiment in the Stratosphere', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The main objective of the project is the development of a balloon borne Lightweight In-situ Tracer Experiment in the Stratosphere (LITES) for simultaneous profile observations of ozone and the long-lived trace gases sulphur hexafluoride (SF6) and the chlorofluorocarbon CFC 12 (CF2Cl2) in the stratosphere. The LITES - package is designed to make measurements up to altitudes of about 30 km (< 10 hPa) if launched on small research balloons with volumes of 10000 m3 or less. The instruments are fully automated. Measurements of the mixing ratios of CFC-12 and SF6 will be made at least every 2 minutes. For data transmission a digital lightweight telemetry system will be developed that is based on standard ozonesonde components that are presently used for routine operations at various radiosonde and ozonesonde stations. The chlorofluorocarbon CFC-12 is a long-lived trace gas, that represents the most abundant source gas of total reactive chlorine, Cly, in the stratosphere and is a good tracer for dynamic transport processes. SF6, is an inert tracer, that provides information about the age of the stratospheric air. In combination with the digital ozonesonde these instruments form a lightweight balloon payload to study the vertical distribution of total reactive chlorine in the stratosphere and quantitatively investigate the corresponding ozone depletion potential in the probed airmass.Two lightweight automated in-situ gas-chromatographs will be developed for the measurement of the long-lived  trace gases CFC-12 and SF6 with a time resolution of 1 to 2 minutes onboard stratospheric research balloons.  Both instruments will use electron capture detectors (ECD) for identification of the measured species. The radio  transmitter of the standard Vaisala radiosonde will be modified for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Effect of zinc and vitamin a supplementation on diarrhea, physical growth and immune response in malnourished children'.

assistant: **Innovation**

To measure the impact of supplementation with zinc alone and a combination of zinc and vitamin A on:* the outcome of acute diarrhoea, particularly the risk of persistence.* moderately malnourished children of 6-23 months of age.Expected OutcomeThe study will assess whether daily supplementation with zinc alone or zinc combined with vitamin A substantially reduces the severity and duration of acute diarrhoea and the nutritional insult of, particularly prolonged, diarrhoeal illness. If so, it is desirable and feasible to implement this reasonable intervention in national programmes, an intervention which will be particularly relevant to the 20% of children who experience recurrent diarrhoea and impaired physical growth.Demonstrating the postulated benefits of micronutrient supplementation has other important programmatic implications, for example in influencing which foods should be promoted during nutritional counselling, the choice of diets to be offered in supplementation schemes and strategies for micronutrient food fortification, e.g. of domestic salt, wheat flour and animal milk.The efficacy of micronutrient supplementation will be assessed in a two-centre placebo-controlled community-based trial where project staff will administer a single large dose of vitamin A upon enrolment and zinc 5 days per week until 12 weeks following recovery.The study will enrol a total of 1,600 children who will be followed up twice weekly to measure the impact on:* enrolment diarrhoeal episode (duration of diarrhoea, number of diarrhoeal stools during the episode, proportion of episodes that become persistent, and change in weight during the episode)* subsequent diarrhoeal morbidity over 12 weeks (incidence of acute diarrhoea and persistent diarrhoea, and daily diarrhoea prevalence)* g