RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Elucidating the enigmatic role of nuclear actin in genomic stability'.

assistant: **Concept**

Nuclear actin-related proteins (ARPs) are stoichiometric subunits of chromatin remodelers and specifically recognize and bind to (modified) histone proteins. In the case of the chromatin modifiers INO80, SWR1 and NuA4, canonical monomeric actin is also an important constituent of these large macromolecular complexes and actively takes part in the remodeling reaction. The main characteristic of actin, however, is its dynamic nature and its capacity to form polymeric actin filaments, which is tightly regulated by a plethora of actin binding proteins amongst them also nuclear ARPs. Interestingly, alteration of actin levels strongly sensitize cells to DNA damage in an enigmatic process and the chromatin-binding nuclear ARPs are obviously strong candidates that possibly couple actin homeostasis in the nucleus with a putative role in genomic integrity. Missing from the field is a genetic approach to specifically mutate actin in the chromatin modifier context and to analyse the impact of polymerization mutants in genomic integrity. The central hypothesis in this research proposal is that nuclear ARP/chromatin remodeler associated actin is a key mediator in genomic maintenance. This assumption is based on the very recent finding in the Gasser laboratory that interference with actin homeostasis renders cells to be hypersensitive to genomic insult as chromosomes are rapidly fragmented in presence of actin depolymerizing agent Latrunculin A and DNA damaging agent zeocin. The major challenge in this project is to bypass the paramount role of actin in the cytoskeleton and to focus on the fraction of nuclear ARP associated actin.This will be achieved by genetically replacing nuclear ARPs with ARP-actin fusion constructs in the budding yeast S. cerevisiae, which will allow me to intro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Hydromechanical coupling in tectonic faults and the origin of aseismic slip, quasi-dynamic transients and earthquake rupture' (HYQUAKE), addressing dissemination and exploitation.

assistant: **Impact**

Earthquakes and tectonic fault slip are among the most hazardous and unpredictable natural phenomena. Fluids play a key role in tectonic faulting and recent research suggests that fluids are central in both human induced seismicity and the mode of fault slip, ranging from episodic tremor and slip to slow earthquakes. However, the lack of accessibility to earthquake faults and the complexity of physical processes has limited our ability to develop holistic models for hydromechanical coupling in fault zones. Geophysical observations have the potential for illuminating precursors to failure for the spectrum of tectonic faulting, however we lack key laboratory data to connect these observations with predictive, physics-based models. The ambitious goal of HYQUAKE is to build a physically based framework to understand and predict fluid pressure induced fault slip for a range of fault motion, from aseismic creep to destructive earthquakes. The HYQUAKE approach is interdisciplinary and at the frontier of laboratory earthquake physics, seismology and data/computer science, with the goal of providing unprecedented quantitative constraints on the key physical processes that couple fault friction, the dynamics of strain localization and fluid flow controlling earthquakes and fault slip behavior. Specifically, I will build a research program around unusually well controlled rock deformation experiments tightly connected to numerical models of faulting. HYQUAKE will integrate lab data on fault zone elastic properties, frictional rheology, and hydromechanical parameters using state-of-the-art experimental equipment built within the project with machine learning to forecast labquake. Details of deformation processes, fluid flow, and fault failure will be imaged using novel acoustic tec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'High-efficiency low-cost solar cells'.

assistant: **Innovation**

Photovoltaic is still the most expensive electric energy due to the solar cell production costs. Many RTD efforts are directed towards making PV panels cheaper and towards other materials with better cell efficiency. Significant changes can be expected only by introducing new technological principles and new materials. Artificial systems self-formation theory applications can be promising solution for changes in solar cell technology. Significant decrease in manufacturing costs for solar cell can be expected from this new approach. The methods of self-formation shows possibilities to produce high quality solar cells with one or two patterning processes instead of four or five. The main aim of the proposal is to introduce high- efficiency (~20%) low cost solar cell manufacturing technology suitable to mass production.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Combating and prevention of concrete cancer in metal reinforced concrete'.

assistant: **Innovation**

Decay of concrete in floors, bridge spans, columns, etc. is a serious problem. It is caused by chlorides and penetration of water in metal reinforced concrete. The long term effects are very serious, since the construction looses its strength. Reparation is expensive. So prevention of decay of concrete is very important. A method to prevent decay of concrete is cathodic prevention (cp). For cpit is necessary to connect all the parts of the metal reinforcement in order to generate a potential difference between the reinforcement (cathode) and a metal anode bar. This process charges the environment by delivery of metal-ions. The objective of the project is to set-up Co-operative Research for the development of a new technique by means of the combination of cp and electro-osmosis, which effects fluid movement in concrete, it is to expect that this new technique will improve highly the present technique of cp: the use of energy will be reduced considerably, the costs of installation are lower, the constructional aspects are rather simple, there is no charge of the environment, less disturbance during repair ands reduction of concrete cover in tunnels, walls etc.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Commercialisation of a robotic platform enabling high-precision force control in multi-dimensional applications' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Current robotic technologies show severe limitations in multi-dimensional applications requiring force control, both from the accuracy and safety perspective. Although combined hardware and control concepts have been developed that enable accurate force control in a single degree of freedom, the majority of tasks necessitates superior force control capabilities in multiple degrees of freedom.Within our ERC grant, we have developed a robotic platform that enables high-precision force control in multi-dimensional applications. This system meets the requirements for safe and high-fidelity body-weight supported gait training of rodents. Our system consists of exchangeable and adaptable elastic force sensing modules that can be attached to state-of-the-art macrostructure robots and enable, combined with specific control laws, highly accurate force control along 4 independent degrees of freedom. The interface consists of a compact entity that is relatively light and can be produced at low costs.Within the ERC PoC ‘Robomed’ the goal is to develop a proposition package for potential investors. On the technical side we will create a novel prototype to validate our robotic technology, which will result in a technical report. In consultation with regulatory specialists a roadmap will be developed to obtain regulatory approval based on the norms and procedures for robotics. A patent protects our robot-assisted training and additional patentability of our findings is currently evaluated. A strategy to overcome any obstacles identified is developed. Market opportunities for our technology include translational research, restoring fine locomotor and manual tasks in humans and industrial applications. These market segments will be extensively analysed and subsequently prioritised withi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Towards a chemically accurate description of reactions on metal surfaces'.

assistant: **Innovation**

This proposal attacks the four major challenges facing theorists who aim to make accurate predictions for reactions of molecules on metal surfaces. The research is curiosity driven, but also of practical importance to an accurate description of heterogeneous catalysis, which enables the production of > 90% of man made chemicals. The central goal is to enable the ab initio computation of chemically accurate barrier heights for reactions with metal surfaces of catalytic interest.In the first challenge addressed, to establish the accuracy of a new electronic structure method we will test whether specific reaction parameter density functional theory (SRP-DFT) can describe reactions like dissociation of N2 on Ru(0001), CH4 on Pt(111), and H2 on Pt containing surfaces of catalytic interest with chemical accuracy. We will try to put SRP-DFT on a ab initio basis by fitting SRP density functionals to single point Quantum Monte-Carlo calculations. Second, we aim to achieve an accurate description of the effect of surface phonons on reaction through implementing Ab Initio Molecular Dynamics calculations on systems like CHD3 + Pt(111), CH4 + Pt(533), and N2 + Ru(0001). Third, we additionally aim to achieve an accurate description of the effect of electron-hole pair excitation on reaction in systems like N2 + Ru(0001) by implementing a new method called Ab Initio Molecular Dynamics with Electronic Friction, using a novel and efficient way to accurately compute the required friction coefficients. The fourth goal is to achieve an accurate quantum dynamical description of the reaction of hydrogen containing polyatomic molecules at surfaces at incidence energies of catalytic interest (in the quantum regime). The quantum dynamics calculations will treat all molecular degrees of freedom a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Wide-Impact cyber SEcurity Risk framework' to be submitted under Horizon 2020.

assistant: **Abstract**

WISER delivers a cyber-risk management framework able to assess, monitor and mitigate the risks in real time, in multiple industries. WISER incorporates socio-economic impact aspects, building on current state of the art methodologies and tools, and leveraging best practices from multiple industries and international initiatives (e.g: NIS). WISER aims at implementing an impressive series of 9 short experiments, in the form of Early Assessment Pilots (EAPs) to test the resilience of different risk management frameworks (taken from different industries and intended broadly) with regards to both traditional and advanced cybersecurity threats. The EAPs allow taking elements that work best in cybersecurity risk management from different frameworks, to then build and implement an advanced risk management system that will be tested & validated in 3 Full- Scale Pilots (FSPs) – with different, high-impact instantiations in the financial services and insurance industry and in the energy field – to demonstrate market acceptance, as well as scalability of a risk management framework for cybersecurity.The WISER framework will ensure cyber risk management becomes an integral part to good business practice in both critical infrastructure & process owners and ICT-intensive SMEs by offering two delivery modes: a pre-packaged solution for addressing basic cyber risk management needs (i.e. SMEs), and a Risk Platform as a Service (RPaaS) mode of operation of the platform, intended for critical infrastructures or highly complex cyber systems requiring the implementation of special controls within the ICT system to be monitored. Ultimately, WISER implements on-demand service composition and ignites innovative assurance models, also from the point of view of premiums determination targeting.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The Maoist Legacy: Party Dictatorship, Transitional Justice, and the Politics of Truth' (MaoLegacy) under Seventh Framework.

assistant: **Objectives**

The proposed research project breaks important new ground by analyzing and documenting how the Chinese Communist Party (CCP) dealt with the legacy of mass atrocities committed under Maoist rule. Most accounts of the period mention the trial against the “Gang of Four” and the accompanying resolution on party history from 1981, which held former party chairman Mao Zedong accountable for grave political errors but not for criminal deeds. However, as yet there has been no in-depth analysis of the roughly five million cases and the over ten million petitions handled by courts and party committees between 1978 and 1987 in order to right previous injustices. Despite its enormous scale and relevance to societal stability, this so-called “revision of unjust, wrong, and false verdicts” has been virtually left unattended to by scholarly research. The project aims at diminishing this gap by studying the CCP’s strategies and the societal consequences of this major policy change. It proposes to analyze the partial break from the Maoist legacy as an important, yet by and large overlooked example of transitional justice, albeit confined by the party dictatorship’s overarching aim to stay in power. By way of relying on a wide array of recently available official and non-official sources, the project analyzes and documents how the CCP selectively dealt with the towering injustices of the past. The project will significantly contribute to current research on China’s transformation process and the Maoist legacy in at least four different areas: First, it will detail the CCP’s standards, institutions, and processes of administrating historical justice; second, it will show the great regional variances in implementing these policies between center and periphery; third, it will offer new expl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Human frontal lobe contributions to executive function and executive dysfunction' (2007-2013).

assistant: **Innovation**

Adaptability is a defining characteristic of the human species. Our ability to solve logical problems, to plan ahead, to focus despite distraction and to adapt when circumstances change far exceeds that of even our closest relatives. These abilities are closely associated with the most developed structure in the human brain: the frontal lobes. When the frontal lobes are damaged, the consequence is can be a debilitating impairment referred to as ‘dysexecutive syndrome’. Dysexecutive syndrome is one of the most commonly documented cognitive impairments across psychiatric and neurological populations. Whilst in many ways, dysexecutive patients may be unimpaired, with normal speech, perception and motor control, they are often unable to lead normal lives, because their behaviour becomes disorganised, disinhibited, maladaptive, and socially inappropriate. The long-term outlook for such patients can be particularly poor as they cannot adapt to their environments or maintain normal relationships. Despite this clinical importance, even the most rudimentary questions regarding how the frontal lobes support executive cognition remain controversial. For example, it is unknown how many specialised circuits exist within the frontal lobes or relatedly what the different forms of executive process are that those circuits support. Consequently, the questions of how dysexecutive patients should most appropriately be categorised and how they may most effectively be treated remain altogether unclear. The overarching aim of the current proposal is to impact on these issues by applying a multidisciplinary research program to: 1) advance our understanding of the neural mechanisms by which the frontal lobes support executive cognition; 2) leverage that understanding in order to provide novel
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Greenhouse Robotic Worker - The first high-performance robotic system for automated harvesting of vegetables in greenhouses' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The goal of current project is to realize the technological scale-up of the first ever efficient and cost-effective robotic harvesting system applied to greenhouse farming of tomatoes. In fact, to date, no commercial product for automated operations ontomatoes is available because of several technological constraints linked with the unstable environment of the indoor farming, as well as with the difficulty to grasp malleable and easily damageable fruits. Metomotion has found solutions to all the challenging technical steps, thereby enabling profitable harvesting of tomatoes and making it possible to growers to harvest the fruits throughout the year and not beingexposed to the labor shortage. By doing so, the harvesting costs are halved and labor reduced by 80%. In the context of thePrecision Farming approach, automation in the agricultural sector is particularly solicited and Metomotion is offering aproduct capable to satisfy the most compelling needs of the growers. The core innovations brought by Metomotion consist of: - Advanced 3D vision system to clearly identify ripe fruits among leaves and stems - Extensible multiple robotic arms to increase harvest speed - Touch sensitive terminals to avoid damage and loos of fruits - Fully autonomous vehicle embedding boxing system for the automated packing of collected fruits. The activities of the Phase 2 projects are related with the enhancement of the prototype performance through optimization of both hardware parts like robotic arm and AGV, as wells  as related SW and User Interface. Interactions with users occurred during Phase 1 project have shown immense interest toward GRoW product from all over the world (about100 expressions of interest collected), thus paving the basis for the successful commercialization of the pro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The role of saponins and saponin-detoxifying enzymes in plant-pathogen interactions' under Fourth Framework.

assistant: **Concept**

Plants have constitutive resistance to infection by several fungi due to the presence of saponins (glycosylated steroidal or triterpenoid compounds) in the cells. Several fungi have developed a way to overcome this resistance by expressing an enzyme able to break down the corresponding saponin. Avenacin A1 and oc-tomatin are two saponins which can be hydrolysed by the enzymes avenacinase and tomatinase, respectively, which are produced by plant pathogenic fungi. Using a phage displaying antibodies library, I will isolate antibodies against these two enzymes able to block their action. I will use the genes encoding these antibodies to transform oat and tomato embryogenic cells to produce transgenic plants resistant to their infecting fungi that can also be used to study more precisely the mechanisms of resistance. To improve the understanding of these mechanisms, I will also generate antibodies against oc-tomatine that can serve for the screening of mutant plants after mutagenesis to obtain tomatin-deficient mutants.