RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Terminology as a Service', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The aim of the TaaS project is to create a cloud-based platform for acquiring, cleaning up, sharing, and reusing multilingual terminological data, one of the most important language resources for industry, academia, and society in general. The motivation of the TaaS project is to address an evident need for instant access to the most recent terms and direct user involvement in the creation and sharing of terminology data. Such a platform will provide a variety of online services for key terminology tasks becoming an integral part of the multifaceted global cloud-based service infrastructure. TaaS services will perform term identification in the user provided documents. The platform will perform terminology extraction and return a list of term candidates. The TaaS infrastructure will ensure an automatic acquisition of translation equivalents for the obtained term candidates in the required target languages. Besides querying major terminology databases, term candidates will be extracted from the huge array of multilingual texts on the web. Users will clean up the obtained data and store it in the shared terminology repository. TaaS will cover all EU official languages and address the terminology needs for both human and machine users. Open access to data, API access to services, reliance on terminology data exchange standards opens a variety of application possibilities. The TaaS project will develop an innovative cloud-based data collection model combining both the latest techniques for automated data extraction and user involvement in data clean-up and sharing. Public terminology resources will be shared via well-established channels for sharing of language resources. Thus, the more users the platform will have the larger volumes of multilingual terminological data will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Validation of α-synuclein Modifications in Parkinson’s dIsoRder Evolution' in the context of a Horizon Europe call.

assistant: **Objectives**

Parkinson's disease (PD) presents a complex challenge due to its progressive neurodegenerative nature, affecting various body systems. Despite decades of research, understanding its onset and progression remains unclear, complicating early diagnosis and treatment. Recent advancements in PD physiopathology suggest promising treatments to slow disease progression, yet reversing cellular degeneration remains elusive. With novel therapies emerging, the need for early detection tools is urgent. However, validated biomarkers for PD diagnosis are lacking, relying on subjective scales like Hoehn and Yahr or costly medical imaging techniques. The accumulation of misfolded α-Synuclein (α-Syn) proteins in PD pathology has sparked interest, but defining diagnostic roles requires further investigation. Recent findings of α-Syn in neuronal-derived extracellular vesicles (NDEVs) from PD patients suggest a potential for novel diagnostic methods. Our proposed project, VαMPiRE, aims to conduct a longitudinal study involving 600 PD patients and 600 healthy subjects to explore α-Syn isoforms and related biomarkers in NDEVs for early PD detection.We plan to develop and validate an innovative in-vitro diagnostic (IVD) test capable of detecting PD's earliest stages and estimating disease prognosis and progression. Utilizing AI models to generate data analysis algorithms and collaboration with leading analytical laboratories and IVD manufacturers, we aim to ensure the reliability and feasibility of the developed prototype. Through consortium efforts, we envision licensing the generated intellectual property to drive the commercialization of our results. This can improve early screening of 270,000 new cases of PD could be detected early and improve the disease management of 9.4 M people current
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Early Stage Research Training on Biomimetic Systems'.

assistant: **Objectives**

The Early Stage Research Training Network proposed here addresses the pressing need for multidisciplinary training programmes, which enable graduate students and young scientists to pursue interdisciplinary research projects. This proposal is about the new research field of Biomimetic Systems which is at the borderline of physics, chemistry, biology, and materials research, and which has a very high potential for future applications in bioengineering, pharmacology, and biomedicine. Biomimetic Systems are model systems in the nano- and micro-regime, which mimic or imitate certain aspects of the complex self-organisation in biological systems. Research on Biomimetic Systems combines experimental and theoretical strategies such as: synthesis of biomimetic nanostructures; construction of experimental model systems; experimental characterisation; manipulation of nanostructures; external perturbations and structural transformations; construction and analysis of theoretical models; computer simulations and molecular modelling; identification of basic mechanisms and general principles.In order to prepare graduate students and young scientists for such interdisciplinary research, we need a new culture of multidisciplinary training programmes which complement the traditional university education. The EST activity proposed here provides such a programme, which integrates the knowledge bases of physics, chemistry, biology, and materials science. This EST should also be effective in order to attract excellent students from all around the world and to counter the brain drain towards the US. In this way, Europe will become the international leader in the training of students and young researchers for this timely and fast growing research field. The EST activity proposed here extends t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Multifunctional Polymeric Nanomicelles Combat Tumor Evasion in Antiangiogenic Cancer Therapy' (2007-2013).

assistant: **Innovation**

Angiogenesis a major contributor to tumor development and metastases. Formation of new blood vessels supports tumor proliferation and disease progression and is often associated with poor clinical prognosis. Recent advances targeting angiogenesis and inhibition of tumor neovascularization has led to the approval of several new antiangiogenic drugs for clinical use in many types of cancers.  Yet despite promising potential, the efficacy of these treatments has been relatively limited. Additionally, as with chemotherapeutics, over time these therapies are associated with tumor resistance and escape. Antiangiogenic therapy (target-specific or broad spectrum) aims to eradicate the tumor by damaging its blood supply; as a result tumor tissue becomes hypoxic and, consequently, necrotic. By current clinical measure, this tissue death is considered a positive outcome; however it is recently discovered that the necrotic tissue in turn releases signals contributing to inflammation and angiogenesis, eventually initiating aggressive revascularization, overriding the foreseen beneficial effects of the antiangiogenic drug. For this grant, we propose to design a novel drug-delivery system based on multifunctional polymer nanomicelles which combine two small molecule drugs: one a potent antiangiogenic drug, and second which is an antagonist of these necrotic signals, combating the feed-back loop which can undermine the positive effects of therapy. Using this innovative approach, we intend to significantly improve cancer treatment by minimizing resistance to antiangiogenic drugs. This technology is based on our previous development of the PEG-PLA polymer conjugate of a small molecule angiostatic compound, TNP-470, which form nanomicelle with improved pharmacological properties compared
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'HYBRID PHOTOVOLTAICS FOR EFFICIENCY RECORD USING INTEGRATED OPTICAL TECHNOLOGY'.

assistant: **Innovation**

The HIPERION consortium has been assembled to answer the call LC-SC3-RES-15-2019: Increase the competitiveness of the EU PV manufacturing industry. The goal of the project is to bring to fruition at the industrial scale a validated high efficiency module-level innovation, based on a disruptive planar optical micro-tracking technology, which concentrates sunlight on multijunction solar cells, mounted on top of a conventional silicon backplate. The resulting high efficiency solar modules (>30% STC under direct sunlight) with a standard flat panel form factor can be mounted on any standard racks or rooftops. The technology has been extensively demonstrated with outdoor tests and pilot installations. It must be now industrialized for mass production, to enable its integration by manufacturers in their existing production lines. The project will demonstrate at pilot-line level the assembly of these high efficiency modules, while several commercial pilot sites across Europe and qualification tests will further validate the performance and reliability.To achieve successfully this 48-month, 13 M€ valued action, a consortium of 16 members representing 9 European countries has been gathered. It includes several industrial players with the key expertise to develop the assembly processes, and some of the most renown European PV centers with strong know-how on design and qualification. A solar manufacturer will do a detailed economical evaluation on the integration of the technology in the production line, while several solar installers will represent both the rooftop and utility end markets. With its novel module architecture and innovative manufacturing processes, HIPERION has the potential to drastically reduce solar electricity costs by significantly boosting the efficiency. It
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Cellular biology of virus infection' to be submitted under Seventh Framework.

assistant: **Abstract**

Viruses are simple, obligatory, intracellular parasites that depend on the host cell for most of the steps in the replication cycle. Not only do they rely on the cells biosynthetic machinery, they exploit cellular processes for signaling, membrane trafficking, intra-cellular transport, nuclear import and export, molecular sorting, transcriptional regulation, etc. To access the full spectrum of host cell functions in the infection of three different viruses in an unbiased and systematic fashion, we will identify the critical host cell proteins needed by monitoring infection in human tissue culture cells after silencing individual genes using genome-wide siRNA libraries and large sub-libraries based on the human genome.   The three viruses are vaccinia virus (a poxvirus), human papilloma virus 16, and Uukuniemi virus (a bunyavirus). They are members of important but poorly analyzed pathogen families representing enveloped and nonenveloped viruses, RNA and DNA viruses, viruses that replicate in the nucleus and in the cytosol. The infection assays to be used are fully automated, and make use of high-content microscopic read-outs for infection and virus production. Identification of the viral  infectomes , in this way, offers a valuable, new perspective into the complexities of the infection process, and opens wide new areas of basic and applied research.   After validation of  hits , extensive biochemical and cell biological analysis will be performed on a selected set of host proteins and pathways identified through the infectome analysis. We will determine which steps in the replication cycle are affected, which mechanisms are involved, and which cellular pathways play a role. For detailed analysis, we will focus on mechanisms in entry, uncoating, and early intracellular
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'HARMONISE' (HARMONISE), addressing dissemination and exploitation.

assistant: **Impact**

In today's Internet based economy, several major actors and an enormous number of small and medium operators are acting in the tourism environment, working separately but using few large standardised platforms provided by few key actors. One bottleneck of the whole system is that the taxonomy identification of the tourism domains and their semantic description are not able to relate the existing architectures in a unique robust structure. On the other side, the Web with its huge possibilities for newcomers creates new standards where it is nearly impossible to impose standardized communication protocols on a semantic level. Following the past initiatives, it seems clear that it is impossible trying to solve this situation creating a meta standard of the tourism, by standardising the main protocols and ontology. Our strategy is to operate a semantic reconciliation able to harmonize the semantic and technological differences existing among the structures, developing an ontology-based solution. The tourism services will be able to cope with different existing standards thanks to the created mapping among each of them.Objectives:The aim of Harmonise is to develop:a consensus process that will compose an enlarged task force on Tourism Standards;identification of a minimal set of concept as a starting point for a mediating tourism standard;a reconciliation that allows the different partners to keep their specific ontologies and proprietary data formats, and carry on effective interactions.This solution appears in opposition to previous attempts to gather all these diverse systems under a unique new standard. The central point of the project is the use of a tourism mapping tool representing core concepts of the tourism domain as well as free software mapping algorithms and sof
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'German Arithmetical Treatises in Manuscripts of the Late Middle Ages (1400-1522). A Study on Philology, History and Culture based on a Digital Edition of the Treatises.'.

assistant: **Concept**

How was the practice of arithmetic developed and spread during the transition between the Middle Ages and the Modern Period? We know a lot about the evolution of mathematical theory and its diffusion in Latin, but little about the way in which arithmetic knowledge spread in the vernaculars in the 15th and early 16th centuries. Translation and adaptation of arithmetic treatises and manuals provided access to mathematical knowledge for new groups of people, shaped the practices of reckoning, and opened new ways of teaching arithmetic skills to persons without higher education. These efforts also endowed European vernaculars with new linguistic forms of abstraction and thus enhanced their potential to serve as a tool in the modern scientific revolution. ARITHMETIC will study handwritten German arithmetic treatises from their first appearance around 1400 until the time when printed reckoning-books became easily available at the beginning of the 16th century. These texts have not been studied before, although they are important witnesses of the vernacularization of mathematical knowledge, of the interdependence of vernacular and Latin pragmatic literacy and of the links between mathematics, sciences, and commerce. The treatises will be transcribed, digitally edited, and analyzed from a historic, literary, and linguistic perspective. An ?Assertive Edition? relying on Semantic Enrichment will be one product of ARITHMETIC. A detailed linguistic analysis focusing on semantics, syntax, the vocabulary, and the transmission context will lead to the reconstruction of an arithmetic discourse, give information on the orality underlying didactic texts and allow tracing writers/compilers and users and their educational and social background. This research aims at a new understanding of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'ERA Chair for Computational Imaging and Processing in High Resolution' under Horizon 2020.

assistant: **Concept**

The aim of the CIPHR project is to establish the Center of Photonics and Computational Imaging (CPCI), a research unit within the University of Tartu (UTARTU) that will become a world leader in Computational Imaging, a sub field of photonics. We will establish this center by recruiting a leading expert in the field to serve as ERA Chair in Computational Imaging and Processing in High Resolution, who will in turn create a top-level research team capable of conducting cutting edge research that combines photonics with the computational power of computer science and optoelectronics. Computational Imaging is a vastly interdisciplinary field; therefore, it has the potential to become one of the most important industries in the future, offering a multitude of applications in 3D imaging, remote sensing, image compression, consumer electronics, security and defense, microscopy and healthcare diagnostics. To account for interdisciplinarity of Computational Imaging, the ERA Chair will build bridges between several fields that UTARTU is already strong at: optics and spectroscopy, machine vision, remote sensing, electronics and informatics. The ERA Chair will also establish strong links with the industrial actors, improve the quality of UTARTU's curricula and work to raise awareness about photonics and the benefits it can offer to society. As a result of ERA Chair's activities, UTARTU will achieve excellence in the field of photonics, develop an efficient system for research exploitation, improve knowledge and skills of future researchers by providing better education to them and raise UTARTU's profile among Estonian and international audiences.


**Keywords:** computational imaging, photonics, Key Enabling Technologies, 3D imaging
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Stacks in Representation Theory, Relative Trace Formula and analysis of  Automorphic Periods' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

One of the central problems in number theory is to prove somereasonably sharp bounds for values of $L$-functions and ofcorresponding automorphic periods (they are usually called ""subconvexitybounds""). In this project I propose to study two  new toolsin representation theory of reductive groups over local fields-- Densities on Stcks and Mirolocalization of representtions.I am going to use these tools  to obtain very strong subconvexity boundsfor periods of automorphic representations. This is an extensionof my recent work with A. Reznikov where we established thesebounds in some special case.These tools will also have many other applications to  problemsin Representation theory and the theory of automorphic forms(e.g. Langlands' functoriality conjecture).""