RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'New tools for forest planning'.

assistant: **Objectives**

The forest management plans are usually paid by the forest owner itself or, in some cases, by the government .A serious problem of the forest management planning is a high price of the plans given mostly by an enormous share of labour in the field on the work. The expenses paid by the owners lead to a lobbying for lowering a quality and content reduction of the plans. Such a trends are dangerous because they can cause difficulties in the sustainability of forest ecosystems development in the future. A solution can be found in searching for new ways haw to elaborate the forest management plans using modern digital technologies. An objective of the prepared project is to find and propose a new technology for a cost and productivity effective elaboration of forest management plans based on combination of digitised data from previous forest management plans, digitised data from the forest management records, growth models, new technology data from the remote sensing of the Earth.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Gender-related differences in expression of microRNAs in cystic fibrosis', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Cystic fibrosis (CF) is a hereditary disease involving a defective ion channel, resulting in altered epithelial cell function and consequent infective/inflammatory airway exacerbations. Progressive loss of lung function is the leading cause of death in CF patients. It is statistically noted that females have a disadvantage in survival and morbidity; this is commonly referred to as the CF gender gap. Recent studies have implicated the female sex hormone, estrogen, in this gender gap. CF patients show altered microRNA expression and some of the affected miRNAs are predicted to target genes encoding key inflammatory mediators such as Toll-like receptor 4 (TLR4) and tumour necrosis factor a receptor associated factor-6 (TRAF6). This highly innovative proposal, to be implemented at the Royal College of Surgeons Ireland (RCSI), aims to study the regulation of key miRNAs by estrogen and investigate if this plays a role in the CF gender gap. I will combine my own expertise in pulmonary innate immunity with the host PI’s world-class knowledge of CF and miRNA research. The research will further our understanding of inflammation in CF to aid development of better therapies. I will develop professionally as I: a) diversify my competencies through the acquisition of new laboratory skills (e.g. qPCR, flow cytometry), b) strengthen my transferable skills (e.g. project management, public engagement, data dissemination) and c) expand my collaborative network through secondments to other world-renowned research teams in Leiden University Medical Centre, Netherlands and University of Heidelberg, Germany. I will contribute richly to research at RCSI as I am already equipped with skills applicable to ongoing work in the team and am keen to take an active role in student supervision. The opp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Biomolecular integration with composite electroactive polymer structures' under Fourth Framework.

assistant: **Concept**

This research proposal addresses a fundamental issue that exists in current techniques for interfacing biomolecules with (opto)electronic devices, namely the design of tailored artificial interfaces that are inherently capable of molecular recognition. Our primary aim is to develop novel strategies that will provide methods for precise control of the spatial distribution and the orientation of complex biological macromolecules immobilised on surfaces, thus creating a fundamental basic skill set for future applications in bioelectronics. In order to address these issues of molecular engineering at interfaces, we have assemblled a consortium of scientists with expertise in nano-fabrication, protein engineering, surface analysis, physical chemistry, and polymer science. Our approach to the subject is therefore multi-disciplinary and convergent", in which we will seek to precisely control the nature of the biological material (through molecular engineering), whilst at the same time, structuring the underlying materials using nano-technology. Necessarily we will also have to bridge the interface between the biological and electronic environments, using tailored thin biocompatible conducting matrices. In this latter respect, we will use functionalised polymers derived from pyrrole, which will be electrochemically deposited on metal surfaces. It is important to note that these polymeric materials have three distinct advantages over other strategies for modifying interfaces (e.g. self-assemblled monolayers). - They are physically robust, giving structural rigour and flexibility tote interface. - The films can be used to modify a wide range of electrode materials,including C, Pd, Au and Pt. - Finally, since the polymer's gross structure is controlled both by the applied electroc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Mechanisms and Treatment of Migraine and its Chronification' (EUROHEADPAIN), addressing dissemination and exploitation.

assistant: **Impact**

Migraine is a common brain disorder, typically characterised by recurring, incapacitating attacks of 1-3 days of severe headache, autonomic dysfunction, and sometimes aura symptoms. The disease affects 15% of all European citizens including children, ranks among the WHO top 12 of most disabling and undertreated disorders, and is responsible for the highest socio-economic burden of any brain ailment in Europe.Migraine attacks typically strike bi-monthly, and in 25% of patients once a week or more. Many patients may progress to “chronic migraine” with near-daily headaches and high disability (chronification). There is desperate need of effective prophylactic treatments to prevent attacks and chronification. Current medications are only moderately effective and often poorly tolerated, mainly due to lack of understanding of how attacks are triggered and why their frequency may increase so dramatically. Overuse of painkillers and triptans, are recognised risk factors for chronification, as are comorbid depression, stress, and obesity. Central sensitisation of pain signalling pathways appears to be pivotal to the chronification proces.EUROHEADPAIN will use established and evolving human and translational animal models to: (a) identify pathways and biomarkers for the triggering and chronification of migraine attacks; (b) decipher the modulatory effects of (hypothalamic) brain circuitries on trigeminal processing, sensitisation, and chronification; (c) assess the effects and mode of action of migraine-provoking molecules; and (d) evaluate the efficacy and mode of action of neuromodulation (in collaboration with an SME) and second messenger-blocking drugs in the treatment of chronic migraine. We expect important spin-offs to the understanding of other chronic pain disorders. The
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Effective reagents to detect and prevent HD, SCA1 and SBMA in presymptomatic humans and to stop progress in afflicted people' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Antiobodies directed against proteins encoded by genes complementary to the regions which encode the (CAG) repeat on the huntington gene, the ataxin 1 gene and the androgen receptor gene will be prepared and humanised. Each antisense protein contains an unstable, expandable polyleucine tract within a plasma membrane spanning helix and is a putative causative factor of the biochemical characteristics of Huntington's disease, spinocerebellar ataxia type 1 and spino bulbar muscular atrophy. The antibodies will be evaluated for use as accurate diagnostic reagents to detect initiation of the disease before clinical symptoms are discernible, to confer passive immunity to the disease and to prevent further progressive neurodegeneration in people afflicted with these diseases.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Automated monitoring in horticulture through spectral analysis with quantum dot detectors and high-resolution optical filters', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The HortiQD project aims to develop an affordable and easy-to-use machine vision system for precision farming. The objective is to build a hyperspectral Short-Wave Infra Red camera working in the wavelength range of 1 - 2 µm with integrated point detection at smaller wavelengths, specifically suitable for orchard monitoring. To reach this goal we propose a novel detector type based on QD technology, based on lead- and mercury-free QDs in compliance with EU regulations and reducing the component cost by approximately 99%. The optical filter will allow for high spectral and spatial resolution, tunable to specific application requirements by design. The hyperspectral images, recorded in-vivo, will be analyzed by deep-learning algorithms in order to identify diseases in an early state and assess the plant health, starting with apples. A data management and correlation system will be set up and present the derived diagnoses and measures directly to the farmer in real-time. The system will be mounted on an already existing autonomous tractor, customized for horticulture, in order to verify the feasibility and targeted TRLs under realistic conditions in several orchard types. HortiQD will help to reduce or avoid the usage of pesticides in European orchards, paving the way towards sustainable farming and increasing food quality. It will scale up the intensity of monitoring by automation, hence, ensure the reliability of European food production. It will help analyze and address the impacts of climate change.The project aims for a fully integrated solution, consisting of several innovative sub components. Each of the developments brings benefit to the industry it addresses and opens up new markets, beyond agriculture and food.


**Keywords:** Hyperspectral Imaging, Colloidal qua
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Fictionalist Mathematical Structuralism' (FICTSTRUCT) under Horizon 2020.

assistant: **Objectives**

Mathematics is ubiquitous throughout the sciences and in everyday language and thought. Its applications across all disciplines - science, economics, engineering, computing and more - are central to the future development of a robust, creative, and driven society. The abstract character of mathematics raises difficult philosophical questions about the nature of mathematical entities (such as numbers, functions, and sets), how we have knowledge of such entities, and how they can be applied in the real world. This research project tackles such questions by integrating two perspectives in the philosophy of mathematics, viz. ""mathematical structuralism"" and ""mathematical fictionalism"". Both structuralism and fictionalism capture important aspects of how many working mathematicians approach their practice. But in contemporary philosophy of mathematics, structuralism and fictionalism are widely thought of as presenting competing views of the nature of mathematics. In contrast, this project will develop a new theory of mathematical structure that unifies structuralism and fictionalism, thereby shifting the debate and promoting new and fruitful lines of research in the philosophy of mathematics and mathematical practice. Crucially, this research will be informed and supported by interdisciplinary discussions of mathematical practice with mathematicians, mathematical scientists, linguists who work on meaning and reference, and psychologists whose research focuses on mathematical cognition. Drawing on aspects of their research, this project will build a new and distinctive positive theory of the nature of mathematics. With this comprehensive theory established, the project will show how it can be deployed to make progress on long-standing problems in the philosophy of mathema
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Development of Microalgae-based novel high added-value products for the Cosmetic and Aquaculture industry' (ALGAE4A-B).

assistant: **Innovation**

Microalgae were always an exciting target for Aquaculture and Biotechnology, as they represent a largely untapped reservoir of novel and valuable bioactive compounds. ALGAE4A-B (ALGAE For Aquaculture and Beauty) project seeks to exploit the microalgae diversity, as a source for state-of-the art high-added-value biomolecules in aquaculture and cosmetics. The diversification of microalgae biomass production towards two independent applications will allow the microalgae industry to gain access to alternative markets in an uncertain, highly competitive and fast changing commercial environment. The project will combine both basic and applied multidisciplinary research in the fields of –omics technologies, biochemistry and applied biotechnology in order to: a) Develop and optimize of low input and application-based microalgae culture systems, b) Develop of “-omic” resources for both microalgae and fishes, c) Develop of downstream processing of high value added products from microalgae, with an emphasis in polysaccharides, proteins, enzymes, antioxidants, d) Develop, formulate and in vitro evaluate a new range of cosmetic and nutraceutical products for aquaculture. The implementation of the project will offer the industrial partners the opportunity to translate scientific research into well defined knowledge-based end products and analytical tools. Apart from scientific objectives the ALGAE4A-B will provide a platform for an efficient dissemination, transfer of knowledge and training between academic, commercial partners and society. Overall, ALGAE4A-B aspires to foster both the European capacity building and the strategic objectives of EU Blue Growth and Marine Biotechnology to harness the untapped potential of Europe's seas and coasts for training and sustainable growth.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'TWO-Dimensional nanomaterial-based metasurfaces for enhanced Plasmonic Sensing' (TWODPS), addressing dissemination and exploitation.

assistant: **Impact**

In the past decade, biosensors have provided an effective way for the physical and chemical science to improve the quality of the life in the modern society. The biosensors are usually based on systems that can detect electronic or optical signals in terms of the concentrations of biological molecules. Thus, it allows the monitoring of molecular interactions from the signal change. Useful applications so far include DNA analysis, glucose concentration test in human blood, sensing of toxins in the water, food and atmosphere. Current challenges for the biosensors are to improve their detection sensitivity and efficiency while with reduced size and operation cost. My research aims to achieve simple, fast and sensitive detection through label-free biosensing technology. For this aim, I will develop a novel plasmonic sensor based on optimized 2D nanostructures with magneto-optic materials for achieving ultra-high sensitivity for the hard-to-identify small biomolecules and explore new physics on the magneto-plasmonic effects generated by the coupling between the 2D nanomaterials and gold/magnetic materials metasurfaces. Miniaturization for commercially portable products embedding those highly sensitive nanostructures will be studied. The proposed research will significantly improve my knowledge in exploiting the optical/magnetic properties of novel plasmonic nanomaterials for enhanced light matter interactions. This project will play a pivotal role for my personal development as an independent researcher and provide me with the unique opportunity to work with experts in the field of materials, electromagnetics and sensing. I will benefit from ideas and inputs from renowned researchers from various scientific disciplines to compliment my background. Moreover, I aim to deliver
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'NOISE IN SPIN ELECTRONICS DEVICES' (MAGNOISE) targeting Fifth Framework.

assistant: **Abstract**

The emerging science of < spin electronics > offers a new exciting way of meeting the need for high-speed sensitive detection of densely stored data. An example of a new generation of electronic devices is the GMR read-head, now commercially available. In common with all electronic systems, noise is expected to limit the performance of this technology, but has not been investigated so far. In magnetic materials noise can be generated by current-related events and magnetic fluctuations whose respective weights strongly depend on the nature of the magnetic systems (e.g. all-metal spin devices, tunnel spin valves or oxide-based spin systems). In addition, the geometry and shape of the devices can greatly influence noise levels because magnetic fluctuations can be of a different nature in very small elements while electronic transport is modified by ballistic effects. The aim of this project is to quantify and understand the different sources of noise in various spin systems (model and commercial) and propose ways of optimising spin devices.OBJECTIVESWe propose to quantify and understand noise sources of magnetic and electronic origins in spin electronic devices and squids used as field sensors by addressing the following issues:- Characterise and understand electronic noise in small magnetic structures including GMR and TMR sensors, patterned perovkites oxide films and multi-layers with high-Tc superconductors and manganites, in a spectral range between DC and several hundred MHz;- Modelling of the noise. Separation of the different sources electrical noise, magnetic domain wall fluctuations. Include the effect of the temperature (phonons, spin waves);- Development of high-Tc squids systems optimised for magneto-encephalography;- Fabrication of high-Tc microsquids for micr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Interdisciplinary school on imaging, modelling and manipulating gene expression regulatory networks (IMMAGENE)', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

Gene expression profiling techniques & detection of molecular events in living cells allowed a first step towards a global & dynamic description of transcriptional regulatory networks. However, in order to exploit the huge datasets & the increasingly complex diagrams resulting from these experiments, a pluralistic approach to modelling & a constant dialogue between in silicon & ex vivo studies is required. We expect new therapeutic strategies to emerge from manipulation &design of regulatory networks involved in multifactorial diseases. This School provides interdisciplinary atmosphere to explore questions such as: What are the dynamic properties of transcriptional regulatory networks? How is the expression of genes involved in the same physiological process coordinated?" How is a robust behaviour achieved in cells despite the variations of individual components? How do the different levels of regulation intermingle?"