RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Hybrid Electric Regional Wing Integration Novel Green Technologies - HERWINGT' in the context of a Horizon Europe call.

assistant: **Objectives**

Development of key technologies to address a new wing design for a HER aircraft maturing up to TRL5: manufacturing, assembly, structural concepts and processes, concept studies, configuration and architecture trade offs for a full wing component are part of the activity. As a physical demonstration concept, the detail design and manufacturing of the relevant components of a centre wing section of a HER Aircraft will be addressed.Conceptual wing studies: configuration and architecture (structural arrangement, Systems allocation and disposition, flight control system) trade offs for a full wing. Full wing structural arrangement mock up for innovative wing concepts, Structural and Multidisciplinary Optimization studies for definition of the optimal structural configuration of wing.Demonstration platform: wingbox, high lift devices, control surfaces, load alleviation devices focusing on the centre section as a demonstration platform:- Integrated Centre section wing box structure with the inner Propulsion stage: Full span (pylon to pylon) torsion box concept representative of more ambitious tip 2 tip concept. Multispar concept, Access manholes and panels, Sustainable aviation fuel and Integrated Fuel vent systems.- Inner section Leading Edges, Integrated Inductive ice protection system integration, Multifunctionality: erosion, impact, Lightning, ice protection, Morphing concepts, Functional tests, Bird strike tests (virtual or real)- Inner section Flap and high lift solutions: Integrated flap solutions. Multifunctionality application to flap.Key processing technologies: Low cost-high integrated out of autoclave technologies. Dry fiber placement and liquid resin infusion for integrated multispar torsion box. Thermoplastic composites processing: In situ consolidation for integ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Coupled-cluster methods for theoretical X-ray spectroscopies' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

To complement the current rapid developments in experimental x-ray spectroscopy, exemplified by a number of new synchrotron installations both in Europe and outside Europe, a strategy for high-accuracy calculations of the relevant physical observables obtained in various modern x-ray spectroscopies is proposed. Specifically, new coupled cluster methods will be developed that allow the theoretical determination of such data with unprecedented accuracy. This will be accomplished by combining the recent developments in general coupled cluster methods with that damped response theory that allows for simulation of finite life-times.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for '3C-SiC Hetero-epitaxiALLy grown on silicon compliancE substrates and 3C-SiC substrates for sustaiNable wide-band-Gap powEr devices' under Horizon 2020.

assistant: **Concept**

Silicon carbide presents a high breakdown field (2-4 MV/cm) and a high energy band gap (2.3–3.2 eV), largely higher than for silicon. Within this frame, the cubic polytype of SiC (3C-SiC) is the only one that can be grown on a host substrate with the huge opportunity to grow only the silicon carbide thickness required for the targeted application. The possible growth on silicon substrate has remained for long period a real advantage in terms of scalability regarding the reduced diameter of hexagonal SiC wafer commercially available. Even the relatively narrow band-gap of 3C-SiC (2.3eV), which is often regarded as detrimental in comparison with other polytypes, can in fact be an advantage. The lowering of the conduction band minimum brings about a reduced density of states at the SiO2/3C-SiC interface and MOSFET on 3C-SiC has demonstrated the highest channel mobility of above 300 cm2/(Vxs) ever achieved on SiC crystals, prompting a remarkable reduction in the power consumption of these power switching devices.The electrical activity of extended defects in 3C SiC is a major concern for electronic device functioning. To achieve viable commercial yields the mechanisms of defects must be understood and methods for their reduction developed..In this project new approaches for the reduction of defects will be used, working on new compliance substrates that can help to reduce the stress and the defect density at the same time.  This growth process will be driven by numerical simulations of the growth and simulations of the stress reduction. The structure of the final devices will be simulated using the appropriated numerical tools where new numerical model will be introduced to take into account the properties of the new material. Thanks to these simulations tools and the new m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Ultra-Efficient Highly-Integrated 1200V Powertrains for Electric Vehicles Enabling Next-Gen Charging Speeds and Compatibility Across Charger Generations' (GEN1200).

assistant: **Concept**

Current mass-market electric vehicles (EVs) commonly operate at a voltage level of 400V. There is however a clear trend to increase the voltage level towards 800V and beyond, as these higher voltages allow for faster charging and lower thermal loads in the system. GEN1200 will focus on modular and scalable 1700V SiC-based power electronics solutions for highly-integrated 1200V powertrains, encompassing technologies for ultra-fast charging while ensuring compatibility with existing charging infrastructure, maximally exploiting the opportunities enabled by higher voltages. The project activities will particularly result in: (i) innovative 1700V SiC power electronics systems with multiple use of components, e.g., the traction inverter will also embed the functionality of backwards compatibility with 400V or 800V DC charging and on-board AC charging; (ii) 1200V electric axle solutions with electrical, thermal and mechanical integration of the power electronics, electric machine, mechanical transmission, and a selection of auxiliaries; (iii) ultra-fast 350 kW charging of novel 10C battery modules with integrated electronics and a modular wireless battery management system for 1200V battery packs. Innovations will be tailored to C-segment vehicles but extrapolation towards other segments will be considered. All activities will be supported by the development of digital twins, as well as control solutions tailored to 1200V systems and for reducing power losses in partial load, and life cycle analysis. Innovative testing methodologies, combining classical component and system characterisation, x-in-the-loop, and experimental vehicle assessment, will cover the wide range of relevant aspects, including efficiency, durability, electromagnetic compatibility and interference, as wel
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Integrated System for driver TRaining and Assessment using Interactive education tools and New training curricula for ALL modes of road transport'.

assistant: **Objectives**

About 40,000 people are killed and 1,700,000 injured each year in accidents in the European Union. A significant part of these accidents involves particular driver cohorts. Scientific studies have shown that a good percentage of these accidents may be attributed to insufficient/inappropriate training, of higher order skills and risk awareness. CBT tools, such as training videos and CD's, multimedia training s/w, static, dynamic VR and AR driving simulators, Ambient Intelligence, cooperative driving-based simulation systems, mobile units and in-vehicle tools have been proposed and used to train relevant skills in small scale projects so far. TRAIN-ALL aims to develop a computer-based training system for different land-based drivers cohorts that integrates multimedia s/w, driving simulator, virtual driving simulator and on-board vehicle sensors into a single modular platform. The new system will be adequate for training and assessment. The core developments will focus on driving simulators, with several prototypes development. New simulation tools will be developed for motorcycle riding, passenger car (novices and emergency drivers) and truck driving. The new tools include also VR-based immersive simulation tools, as well as a common architecture (ontologies-based) and a modular simulator design process for multi-user groups. The new simulation tools will have many innovative features, such as AmI-based traffic participants, virtual instructor guidance, ADAS/IVICS training modules and will support co-driving, cooperative and group training, remote networking, dynamic scenario management, enhanced reality representation and adaptive training. The developed tools will be tested and optimised in 11 pilots Europewide, aiming at products, guidelines, standards, certification a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Towards a self sustaining European Technology Platform (NERIS-TP) on Preparedness for Nuclear and Radiological Emergency Response and Recovery' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

This project aims on the one hand to keep the momentum gained through the European Project EURANOS in establishing a platform where the operational and research community can meet and discuss with all the relevant stakeholders the topics related to emergency response and recovery preparedness and on the other hand to tackle urgent research topics in the area of nuclear emergency response and recovery preparedness. It addresses the call Fission-2010-3.3.1: European platform on emergency and post-accident preparedness and management. Through a collaboration of industry, research and governmental organisations in Europe, methodological aspects and computational models will be developed to be consistent with recent recommendations from international bodies such as the ICRP (International Commission of Radiation Protection) and improve Europe’s response by coupling the decision support systems with an early notification system such as ECURIE. Within this project, a platform will be established that will be a unique place for combined meeting of the research and the operational community.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Mapping the Controllosphere'.

assistant: **Concept**

The sensation of cognitive effort is integral to everyday human experience, is a core construct in psychological theories of behavior, and contributes to multiple psychiatric disorders like ADHD and depression. However, despite decades of study the neural origin and functional purpose of cognitive effort remain poorly understood. This constitutes one of the most important outstanding questions in cognitive neuroscience and a major challenge to mental health research. Recently, I proposed a new, mathematically formal theory of cognitive effort that draws together concepts from dynamical systems analysis, linear control theory (LCT), artificial neural networks (ANNs), cognitive psychology and neurophysiology. The theory relates cognitive effort to the fact that brain neuroanatomy and neurophysiology render some neural states more energy-efficient than others. In particular, I introduced the concept of the ""controllosphere,"" an energy-inefficient region of neural state space associated with high cognitive control, and proposed that cognitive effort serves to move the system state out of this high-energy region.The goal of this project is to test the controllosphere theory. I will use ANNs to simulate human behavioral and neural data collected in tasks that require mental effort, and apply LCT to these models to make formal predictions about which neural representations are more or less effortful. I will then test these predictions using a wide variety of empirical techniques in a series of experiments with human participants. The establishment of a verified formal theory of cognitive effort will fill an important gap in the cognitive neuroscience of cognitive control, strongly impact clinical practice, and provide important insights for the development of novel artificia
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Highly efficient and eco-innovative probiotic food supplement for antibiotic-associated disorders prevention' in the context of a Horizon 2020 call.

assistant: **Objectives**

Development of novel probiotic solutions for specific illnesses and health problems, ex: Obesity, Depression, Crohn or Colitis diseases.The solutions proposed by MyBiotics will use Mycrobe TM a delivery technology to overpass the biologic barriers :gastric acid, pancreatic juice and bile salts, and deliver sufficient quantity of living probiotic directly to colonize the gastro intestinal tract were they are therapeutically efficient.MyBiotics will design for each targeted disease a set of specific bacteria and validate their selection by using MycrobeTM as leverage to provide unreached comfort and easy variation during the selection and test of the probiotics.The ambition is to provide pharmabiotic solutions for specific diseases and provide robust clinical results for lobbying activities with the EMA, EFSA and FDA for the regulation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Cultural Heritage Analysis for New GEnerations', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Cultural heritage (CH) objects have been constantly undergoing changes/degradations over time. In order to pass the legacy of these objects to future generations, it is important to monitor, estimate and understand these changes as accurately as possible. These investigations will support the conservators to plan necessary treatments in advance or to slow down the specific deterioration processes. The dynamic characteristics of materials vary from one object to another and are influenced by several factors. To detect and predict their changes, accurate documentation and analysis are necessary. Over the years, CH digitization using scientific imaging techniques has become more widespread and has created a massive amount of datasets of different forms in 2D and 3D. Several past projects focused on different aspects of technological developments for better digitization methods. There has been less focus on the processing and analysis of these datasets to make the greatest use of them and to their further exploration for monitoring ‘changes’ in CH artefacts for conservation purposes. The lack of adequate digital tools for monitoring these changes is related to material behavior and stability, which still need to be addressed. The proposed project will take cultural heritage digitization to a new level by exploring digital datasets for deeper analysis and interpretation. The main idea is to develop methodologies for the assessment of changes in CH objects by comparing and combining digital datasets captured at different time periods. The validity of the methods has to be evaluated through case studies conducted in collaboration with CH experts and stakeholders. The project is an interdisciplinary approach combining expertise on imaging techniques, computing, CH, and conserva
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'European vaccine effort against HIV/AIDS - III' (EUROVAC-III).

assistant: **Innovation**

A vaccine against HIV-1/AIDS is urgently needed to slow down the current epidemic in both Africa and Asia. The predominant subtype of HIV-1 causing the AIDS epidemic in Africa and Asia is subtype C. Clinical lots of priming agents - Gemlike Forest virus (SFV) and naked DNA -, as well as a boosting agent - the attenuated poxvirus strain NYV AC -, are prepared; all vaccine components are derived from HIV-1 subtype C and include the gag, poll, net and envy genes. The objective of the Euro Vac-III demonstration project is to identify the best priming agent, DNA vs. SFV, that allows for reduction of the NYVAC dose without significant loss of immunogenicity. This demonstration project aims for the establishment of the most immunogenic vaccine that is suitable for mass vaccination and forms the last step towards moving into phase IIb and III efficacy trials.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'P53-mediated apoptosis - the contribution of p53-mediated transcriptional repression' (1994-1998).

assistant: **Innovation**

Inactivation of the P53 gene plays an important role in cancer. One of the main functions of p53 protein is to elicit apoptosis in cells which have sustained genomic damage or that have undergone other | alterations which predispose them to become cancerous. There is an ample evidence that p53-mediates apoptosis is central to the function of p53 as a tumor suppressor in vivo. The mechanisms involved in the p53 mediated apoptosis are yet unknown, but p53 has recently been shown to transactivate the bax gene, whose product promotes apoptosis when present in excess. Furthermore, the wild type p53 protein can act also as a transcriptional repressor, and recent studies suggest a relationship between the p53-mediated transcriptional repression and apoptosis, opening a new way to better understanding the mechanisms involved in programmed cell death. The present project aims to determine the contribution of p53-mediate, transcriptional repression to apoptosis. Among the main methodologies used will be: use of differential display to clone genes selectively repressed by p53 in cells wich undergo apoptosis; attempts to reverse apoptosis by upregulating the levels of p53-repressed genes, in transient transfection assays as well as through generation of stable cell lines with inducible expression. It is espected that the findings will provide a better understanding of the molecular biology of p53-depende apoptosis. The impact in an area wich is the focus of much extensive research is espected to be real important. The present project also provides an excellent opportunity for high quality training in advance research methodologies.