RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Repair of tissue and organ damage in refractory chronic graft versus host disease after hematopoietic stem cell transplantation by the infusion of purified allogeneic donor regulatory T lymphocytes' (TREGeneration) under Horizon 2020.

assistant: **Objectives**

Our proposal encompasses parallel clinical trials addressing the feasibility and the effectiveness of donor-derived regulatory T cells (Treg) as a therapeutic agent in the treatment and prevention of tissue and organ damage resulting from graft versus host disease (GVHD) after hematopoietic stem cell transplantation (HSCT).We propose a collaborative clinical study in which Treg therapy for GHVD is the common dominator. However, by bringing together several clinical centers with expertise in this area, we are also having the opportunity to simultaneously address other issues that would not otherwise be addressable by each clinical center on its own. Firstly, by using different Treg preparation strategies, we will be able to determine whether ex vivo isolated Treg are sufficient or whether in vitro expansion and subsequently higher dosages are required. Secondly, we will investigate if sole Treg infusion is effective or if rather co-administration of therapeutic agents that are likely to induce Treg survival and expansion in vivo (rapamycin; IL-2) is required for a successful response to Treg therapy.The studies on GVHD treatment outcome will be pursued together with a detailed analysis of immune monitoring, comprising T cell receptor clonotype tracking and tissue regeneration markers, in order to further understand the mechanisms underlying the therapeutic and regenerative potential of Treg cells.   Our consortium has developed a concerted approach to the topic of Treg therapy in GVHD. This is a unique opportunity to determine the validity of this cellular immunotherapy approach in GVHD prevention and treatment, with potential for a significant impact on patient quality of life, survival rate and ultimately on the quality of health care provided.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Increasing the impact of Central-Eastern European environment research results through more effective dissemination and exploitation' (ENVIMPACT) under Seventh Framework.

assistant: **Objectives**

Based on indications from EC and FP7 statistics, the Central and Eastern European (CEE) countries participate at low rate in the FP7 Environment theme. On the other hand air pollution, chemical pollution and environmental risks should be handled with expressed interest in this region, due to severe environmental damages caused by decades of negligence and mishandling. CEE researchers have been conducting research in the mentioned fields since the middle of the 20th century, however, their results did not reach – and influence - either the policy makers of their own country, or their academic counterparts in EU-15.The main objective of ENVIMPACT is to enrich the EU knowledge base with the environment-related results of the CEE researchers, thus inducing new collaborations under FP7/FP8 which may lead to innovative solutions for the lasting protection of our environment.Using local contacts, knowledge and the insight of expert groups consisting of relevant academic, industrial/ETP and policy representatives, the innovative environmental research practices and results originating from Central and Eastern Europe will be identified, mapped and made available for the governmental, academic and industrial stakeholders all over Europe. After analysing the presently applied dissemination and exploitation practices of CEE research results (by SWOT analysis), good and bad practices will be presented in an online catalogue. Recommendations will be prepared for the development a taylor-made toolkit. To close the communication gap, CEE researchers will be offered trainings and online mentoring services, based on the recommendations for communication and exploitation of research results.Partners from 7 NMSs will ensure the availability of local research results, while representatives
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Development of an innovative welding process for the rapid assembly of thermoplastic brackets to thermoset-matrix composite structures' to be submitted under Horizon 2020.

assistant: **Abstract**

The general objective of the BRACKETWELD project is to contribute to the green and cost-efficient integration of system and aircraft structure by the development of an innovative technology for the rapid assembly of thermoplastic brackets in general, and in particular PEI brackets, to thermosetting composite components currently used in aircraft structures.This innovative assembly technology is based on the idea of using the fast and efficient ultrasonic welding technology to assemble thermoplastic brackets to thermosetting composite structural components. As thermosetting materials cannot be welded, a thermoplastic surface media will be strongly attached to the thermosetting composite structure by a co-curing process, being this surface media used as an anchor interface for the latterly welding of the thermoplastic brackets by any fusion bonding technique, and especially by the ultrasonic welding. The key challenge for the development of this innovative technology will be the development of the appropriate surface media that must be compatible with the typical thermoplastic materials used for the injection of brackets, while at the same time achieving a high adhesion strength to the thermosetting composite laminate during the curing of the structural components. The integration of brackets into the structure of the aircraft will lead to significant weight, manufacturing costs and energy reductions compared to the current adhesive bonding methods, since is that there is no need for surface preparation, adhesives, and curing time nor expensive quality control procedures. The project is launched under the Platform 2 of the Large Passenger Aircraft IADP (LPA), “Innovative Physical Integration Cabin–System–Structure”, orientated to the development, assessment and selection
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'New Classes of Engineering Composite Materials from Renewable Resources', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

Future product design requires sustainable processes in material development. A break-through approach will use new engineering materials-biocomposites completely made from natural resources-and their manufacturing being knowledge -based. Resource saving, variability in properties, functionality, low costs and eco-efficiency concern the product life cycle. Driving forces are SMEs from less RTD intensive branches producing raw materials of biomass, fibres, wood constituents and biopolymers to supply broad industrial branches in the future. A sustainable breakthrough will be gained if high tech materials are made in contrast to current existing low grade wood plastics and packaging materials to provide substantial profits to raw material supplier and material developer. The objective is to obtain innovations on engineering thermoplastic and thermosetting materials mainly from natural resources, like lignin from the paper industry and a Hydrothermolysis, other biopolymers Polylactide,Polyhydroxy-butyrate,Starch,Furan resins, fibres and fibre mats. The RTD includes the path from raw materials to final top quality engineering composite materials and model products (covers for electronic equipment, car front end, glass frames etc.). Demonstration by prototypes will support dissemination and exploitation of results and will show the benefits of the materials. A concept of sustained skill and training for staff and students will provide work routines and material data access. Such a programme can only be achieved by SMEs if sharing knowledge and equipment being assisted by research centres. The collaborating SMEs expect to increase their capacity and employment by the order of 10% to capitalise on the project. Dissemination and exploitation will enable transfer to plastic and b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'The European Network of HE Cluster 4 Industry National Contact Points', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The mission of the NCP4Industry - Cluster 4 Industry NCP Network is to set the basis of equal and consistent National Contact Points' services on the industry sector, by facilitating trans-national co-operation between NCPs within the Cl4 Industry and by fostering the circulation of knowledge, good practices and available opportunities among industrial research and innovation communities. The Cluster 4 Industry NCP Network is the main source of practical information and assistance in participation in the Cluster 4 Industry related Destionations and Topic Calls of the Horizon Europe Framework Programme. The network will support the Cluster 4 Industry National Contact Points (NCPs) and the European R&I community.The new consortium consists of 17 officially nominated NCP organizations and has an excellent representation from Member States,  Associated Countries and Widening Countries. Nevertheless, the entire network of CL4 Industry NCPs goes beyond these 17 project beneficiaries: NCP4Industry counts with all CL4 Industry NCPs not only by offering tailored support, but also by including them in the planning of activities in order to meet their needs and the needs of their clients.The R&I community will benefit from NCP4Industry, accessing relevant background information about HE Industry related calls for proposals, benefiting of matchmaking events, mentoring and training activities, and enhaning the access to funding opportunities thankful to knowledge transfer and communication measures. The NCP4Industry project outcomes will therefore lowering accessing barriers to European funding, through a consistent level of European and National services provided by the National Contact Points across Europe and beyond.


**Keywords:** National Contact Points, capacity building, tra
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Renewal, Innovation and Change: Heritage and European Society'.

assistant: **Objectives**

For many in 21st century Europe, Cultural Heritage (CH) is more about what it is than who we are:  though enormously rich, this treasure is often locked away, or crumbling, or in a foreign language, or about a past which to many people - young , old, newcomers to Europe and settled inhabitants - seems of little relevance. But this is changing. As digital technologies permeate all of society, compelling us to rethink how we do everything, we ask questions: how can CH institutions renew and remake themselves? How should an increasingly diverse society use our CH? How may the move from analogue to digital represent a shift from traditional hierarchies of CH to more fluid, decentred practices?  How, then, can the EU citizen, alone or as part of a community,  play a vital co-creative role? What are the limitations of new technologies in representing and promoting CH? How can CH become closer to its audiences of innovators, skilled makers, curators, artists, economic actors? How can CH be a force in the new EU economy?RICHES will research answers to these questions by drawing together 10 partners from 6 EU countries and Turkey, experts from cultural institutions, public and national administrations, SMEs, the humanities and social sciences. Its interdisciplinary team will research the context of change in which European CH is transmitted, its implications for future CH practices, and the frameworks - cultural, legal, financial, educational, technical - to be put in place for the benefit of all audiences and communities in the digital age.RICHES will employ traditional and innovative research methods and tools; case studies will focus on copyright/IPR, the commoditisation of CH, performance-based CH;  evidence-based reports, recommendations and guidelines will be produced for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Nutritional influence of vitamin A on the expression of genes involved in the morphological development of sea bass larvae' (NIOVOTE) targeting Fifth Framework.

assistant: **Abstract**

The rate of malformed fish larvae varies depending on the nature and level of some dietary nutrients, in particular peptides and phospholipids. Some authors have shown the influence of retinoic acid on the skeletal formation process by acting on the expression of some developmental genes.In this sense, among the possible developmental genes, the present project is focused on two families:1) the Hox gene family, which controls the growth of cartilage precursor cells (some of these genes are modulated by retinoic acid in marine fish larvae during the first after hatching) and2) the hh gene family, coding for signal molecules and for growth factors, controlling different steps of the morphogenesis and cell regeneration (these genes code in particular for proteins involved in the cell-cell interactions, and play an important role in the skeletal formation).Consequently, the possible involvement of Hox and hh genes in malformation processes induced by nutrition is worth to be investigated.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'MOLecular Materials for Passivation in large Area Perovskite Solar modules' (MOLMAPS) targeting Horizon Europe.

assistant: **Abstract**

Perovskite solar cells (PSCs) have emerged as highly promising next-generation photovoltaic technologies, distinguished by their exceptional combination of superior photovoltaic performance and cost-effective manufacturing. Despite their remarkable potential, the commercialization of large-area PSCs remains a formidable challenge, presenting a critical obstacle in the field of perovskite photovoltaics. The core objective of this project is to spearhead the development of efficient and durable perovskite solar modules (PSMs) that are pertinent to industrially relevant scale. We aim to demonstrate power conversion efficiencies of 23% and 20% on 100 cm2 and 800 cm2 modules, respectively. To achieve this ambitious goal, we will adopt an interdisciplinary approach, to devise a novel strategy for absorber and interface engineering on a large scale. This breakthrough method will enable uniform crystal growth on a large scale, resulting in perovskite films with high homogeneity and creating interfaces with nanoscale uniformity and robust interfacial adhesion in large-scale modules. The stability of these modules will undergo rigorous testing in accordance with IEC and ISOS protocols. Simultaneously, alongside the device/module fabrication and stability testing phases, we will embark on fundamental investigations utilizing advanced techniques to gain a comprehensive understanding of the material's operational mechanisms within the modules. This project capitalizes on the host lab's extensive proficiency in perovskite module fabrication, which is complemented by the applicants strong background in material design and synthesis. This project will not only significantly enrich the fellow's skill set but also instill invaluable leadership qualities and management skills poised to sh
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'LARGE MULTIPURPOSE PLATFORMS FOR EXPLOITING RENEWABLE ENERGY IN OPEN SEAS' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The PLENOSE project aims at establishing a multi-disciplinary network between European, North American and Indian institutes. From the perspective of an exchange of competencies, the objective of PLENOSE is to share the expertise of the partners in the fields of Marine Engineering, Structural Dynamics, Reliability Assessment, Random Processes and the necessary skills for performing experiments in artificial and in natural basins. The scientific goal of the PLENOSE project is to define and validate a technique for the design of artificial islands consisting of floating or fixed structures, with the well-defined purpose of exploiting renewable energies in open seas. The multipurpose ‘energy island’ may produce energy from sun, wind and waves, with several advantages. For example, the global downtime is reduced if different sources of renewable energy are considered: if wind does not blow, electrical power may be produced from waves (with swells) and/or sun, and so on. At this purpose, pertinent dynamical models and adequate experimental models are exploited in order to disseminate the problems occurring at the design stage. Novel methodologies in the field of stochastic dynamics (e.g. Wiener Path Integrals, Wavelets based statistical linearization) are analysed for performing random vibration analysis. Moreover, innovative wave energy converters, based on the principle of the Oscillating Water Column, are investigated for maximizing the harvesting capability of the plant.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Gene therapy of inherited and acquired hearing loss', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

To address the substantial financial and social burden caused by hearing loss in 360 million people world-wide, I aim to improve hearing via gene therapy to correct inherited and protect from acquired hearing loss. In vitro experiments will establish the best vector configurations for transfer of therapeutic genes and miRNAs into inner ear hair cells (HC) and spiral ganglion neurons (SGN). The efficiency of the best-performing vector designs will then be explored in vivo using fluorescent marker proteins. Cell-type specific and inducible promoters as well as receptor-targeted vectors will be employed as a safety measure and to ensure transgene expression in HC and SGN target cells. Once efficient transduction of appropriate target cells and proper expression of therapeutic proteins are demonstrated, I will perform proof-of-concept studies in hearing loss models, incl. established mouse models, to correct (WP1) or protect (WP2) from impaired hearing. To ensure translatability of these findings, I will generate human induced pluripotent stem cells (iPSC) from patients with hearing loss (WP3), so that I can test optimized constructs in human otic cells. Moreover, I have access to a collection of well-characterized samples from over 600 hearing loss patients, including children with congenital hearing loss in whom many novel monogenetic alterations were identified. These resources provide the unique opportunity to generate a novel toolbox for the treatment of hearing loss. In addition to lentiviral and adeno-associated viral (AAV) vector delivery of corrective or protective genes to treat hearing loss, I will apply state-of-the-art genome editing tools to model and correct mutations causative for hearing loss in cell lines, primary cells from murine models, human patients a