RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Chemical vapour deposition of Chalcogenide materials for phase-change memories'.

assistant: **Innovation**

Chalcogenide-based phase change materials (which contain at least one element from Group VI in the periodic table: Te, Se,or S) have recently generated strong attention for electronic memory applications, due to their success as optical storage media. Phase-change memories (PCM) are one of the most promising candidates for next-generation non-volatile memories, having the potential to improve the performance compared to Flash memories as well as to be scalable beyond Flash technology.One technological issue is the phase-change layer deposition process, which principally determines the implementation of the material properties. Phase-change films are currently grown by sputtering, a physical vapour deposition technique, which has yielded demonstrator chips. However, for continued down-scaling for high-density nanoelectronic devices and lower programming currents, greater control of film deposition over non-planar structures is than possible with sputtering is necessary. Despite this need, no other deposition routes are available nor widely studied.Overall ObjectivesThe project therefore aims at the development of a film manufacturing process based on a chemical-based technique, metal-organic chemical vapour deposition (MOCVD). MOCVD enables the production of thin films with superior quality compared to those obtained by sputtering, especially in terms of conformality, coverage, and stoichiometry control, and allows implementation of phase-change films in nanoelectronic devices. The main phase-change chalcogenide material system that will be investigated is Ge2Sb2Te5 (GST). Once a suitable process is developed, it will be used to fabricate state-of-the-art memory cells at the 90/65 nm node, and the electrical performance compared with standard devices based on sputtered G
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Why are the Big Two of Agency and Communion so Fundamental to Human Psychology? An Agency-Communion Theory (ACT) of Social Learning and Cultural Activity and Its Novel Account of Social Influence'.

assistant: **Innovation**

The Big Two of agency (influence, resourcefulness, authority) and communion (benevolence, prosociality, honesty) are fundamental to human social cognition, the self-concept, and personality. The Big Two must have a tremendously important function for humans, otherwise they were not that fundamental to human psychology. Yet, what is this function? State-of-the-art answers explain the function of the Big Two either in social cognition or in the self-concept or in personality and those answers contradict each other in critical ways. Here, I propose the first all-encompassing answer to the functional question of the Big Two in social cognition and the self-concept and personality. My answer comes in the form of a novel theory: Agency-Communion Theory (ACT) of Social Learning and Cultural Activity. According to ACT, the Big Two are the chief enablers of high-fidelity social learning. Never before have the Big Two been considered relevant for high-fidelity social learning, but the latter is widely seen as the reason for humans’ capacity to build culture and thrive by cultural activity—humans’ most powerful evolutionary strategy. Thus, ACT considers the Big Two the essential building blocks of human cultural activity and, ultimately, of humans’ extraordinary evolutionary success. ACT’s novel portrayal of the Big Two entails a wide variety of previously unforeseen behavioural consequences, including a novel account of social influence. The state-of-the-art account presupposes the existence of an innate tendency to conform to majority norms. ACT questions the existence of such an innate tendency and offers an alternative with far-reaching implications for many theories across social sciences and urgent societal challenges in the sphere of social influence. My interdisciplinary t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Boronic Acids as a New Strategy to Boost beta-Lactam Antibiotics for the Treatment of Tubercolosis' (BAN-BOOT), addressing dissemination and exploitation.

assistant: **Impact**

Tuberculosis (TB) is a highly infectious disease caused by Mycobacterium tuberculosis (Mtb), one of the most dangerous aerobic bacteria. The need for long-term treatments and the increase in drug resistance mechanisms make it necessary to urgently develop new strategies to combat this potentially lethal pathogen.  beta-Lactam Antibiotics (BLA) are the most widely used and safest antibiotics in the clinic and include several classes such as penicillins, cephalosporins and carbapenems. However, historically these agents have not been used to treat TB. There are two mechanisms of resistance to BLA in Mtb: the cell envelope rich in lipoglycans which acts as a barrier for the penetration of many drugs, including BLA, and the expression of BlaC, a specific beta-lactamase enzyme capable of hydrolyze and inactivate the BLA. Recent studies have shown that the combination of meropenem (a beta-lactam carbapenem), amoxicillin (a beta-lactam penicillin) and clavulanate (a beta-Lactamase inhibitor) markedly reduced the Mtb load in the patients sputum after two weeks, therefore giving new hope to the use of BLA to tackle the tuberculosis epidemic. This proposal aims to develop new compounds that behave as BLA adjuvant for anti-Mtb treatment with a dual mechanism of action. We will design and synthesize novel Boronic Acid Transition State Inhibitors (BATSIs) as inhibitors of BlaC, the beta-lactamase expressed in Mtb, and investigate whether they can be derivatized to become disrupting agents of Mtbs unique outer capsule made of lipoglycans, to promote better penetration of drugs into the cell. This project will also investigate the possibility of improving the penetration of molecules into the necrotic granuloma formed in vivo as part of the disease process, by developing a lipid-based
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Developing a novel methodology to assess ingestion, bioaccumulation, and impacts of micro- and nanoplastics in marine planktonic biota.' (PlaSeatic) under Horizon Europe.

assistant: **Objectives**

Microplastic pollution is an issue of increasing concern for the ecosystems and human health. In the last decade, microplastic ingestion and impact in biota has received significant attention. Despite the extensive research conducted, there is still need for improvements in the methodologies used for sample analysis. PlaSeatic aims to provide a new methodology for quantification and characterization of micro- and nanoplastics (MNPs) ingested by organisms in aquatic systems. This method seeks to surpass traditional techniques by reducing the risk of cross-contamination, lowering the size detection limits, preventing alterations and plastic loss while retaining the biological context of the particles.PlaSeatic will focus on copepods, which play a critical role in marine food webs and global geochemical cycles. However, with some adaptations, this methodology could be applied to other organisms or even human tissues.  Additionally, this improved methodology could be implemented by other research groups, thereby, increasing homogeneity and accuracy in microplastic research— an urgent need recognized  by the scientific community in this field.To achieve the objectives of the project, PlaSeatic rely on the synergy between my expertise in the assessment of ingestion and impact of microplastics in marine food webs and the extensive expertise on chemical engineering, microscopy and spectroscopy of the host (Prof. Roeffaers). This will be further supported by Dr. Pedrotti (supervisor in secondment), whose vast knowledge on plastic pollution and access to historical plankton samples will be invaluable to the project. PlaSeatic will raise public awareness about the impact of plastic pollution. Scientifically, it will enhance our understanding of MNP ingestion, bioaccumulation and i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Strings'04'' (STRINGS04).

assistant: **Concept**

The main goal of String Theory is to supplant the current unified theory of fundamental interactions, the Standard Model, and to include it (as a low energy approximation) in a coherent and complete description of quantum gravity, much as quantum mechanics included classical physics as a limiting case. The area of string theory is certainly one of the most active fields of research in theoretical physics today precisely because it addresses such a fundamental question. String theory has had many important successes in the last ten years but is certainly not a complete theory at the present time. Many important problems remain and it is the aim of this conference tore views them in a thorough way. STRINGS04 will be the most important conference in 2004 devoted to all aspects of strings theory which besides quartering gravity include its relation to particle phenomenology, its applications to cosmology and its interplay with many areas of mathematics. It will gather most of the world leaders in the field in the prestigious and newly renovated setting of the College deFrance. To empower the largest number of young scientists to attend the conference and fully benefit format, a weeklong school, to be held at the Institute des HautesÉtudes Scientifiques, where a series of pedagogical lectures will be delivered by some of the best lecturers, will precede the conference itself. This school is an integral part of the present proposal. The last day of the conference will be devoted to a series of public lectures open to non-specialists. The organizers have a long and successful experience in setting up conferences and training events.'
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'System-wide analysis of intrinsic protein properties affecting proteome homeostasis upon abiotic stress in green algae' (Stress-proteostasis) under Seventh Framework.

assistant: **Objectives**

Abiotic environmental stresses such as extreme temperatures represent serious threats to plants and are a main reason for significant agricultural crop losses every year. Hence, an understanding of the molecular consequences of stress exposure and the underlying principles of plant stress responses are fundamental questions in biology and provide the basis for the genetic engineering of stress resistant crop plants. In particular, high temperature stress leads to an increase in protein unfolding, misfolding, and aggregation and thus challenges proteome homeostasis (proteostasis). As a response, cells increase the expression of molecular chaperones to maintain proteostasis by counteracting protein misfolding and aggregation.The overall goal of this study is to globally identify properties of fragile proteins in plant proteomes challenged by heat-shock exposure. We will use the unicellular green algae Chlamydomonas reinhardtii and Nannochloropsis sp. as model organisms to monitor protein misfolding and aggregation under physiological conditions, mild stress and severe temperature stress. We will apply quantitative proteomics and bioinformatics to reveal physicochemical properties characteristic for proteins prone to misfolding and aggregation. By this, we will further identify proteins that have a high dependence on protection by molecular chaperones. Based on this system-wide analysis individual proteins will be engineered with the goal to optimize their conformational stability for improved stress tolerance.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'A Water-Soluble Packaging to Unlock New Markets' (ECOLACTIFILM), addressing dissemination and exploitation.

assistant: **Impact**

Lactips is an innovative company located in France, founded in 2014. Lactips develops a disruptive thermoplastic material, water-soluble at room temperature and below, for uses in water-soluble or edible packaging. This material is unique on a worldwide scale. Based on milk protein, Lactips’ thermoplastic pellets show besides a full biodegradability in less than three weeks (it can even be thrown away in one’s home compost), is highly printable thus perfect for information and marketing purposes, presents a very good barrier to oxygen and can further be functionalised.Its unique water solubility property allows Lactips to answer chemical manufacturers needs for better single doses packaging in laundries and dishwashing. Moreover, it opens up new market opportunities such as detergent packaging for water treatment (swimming pools) and agrochemicals, where single doses cannot be used currently as current packaging is poorly soluble below 30°C and does not answer requirements. Users (consumers, farmers, employees) will not be in contact anymore with harmful chemicals and will control the amount of chemical they add in water. This will result in a better user safety and a better preservation of our environment.The ECOLACTIFILM is Lactips’ project to remove every barrier and properly address the market. Properties will be improved for our material to resist to liquids, acid and alkaline powders and to be shrinkable.At the project end, every chemical that are to address water trouble could be packaged in a sound and clean, harmless way.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Doctoral Training Network for Quantum Enhanced Optical Communication Network Security' to be submitted under Horizon Europe.

assistant: **Abstract**

The security of data has never been more valuable. Today, cryptography is critical to the safe operation of digital infrastructures. However, yearly advances in quantum computing present new threats. Quantum Key Distribution (QKD) may provide the best protection, an approach designed to ensure privacy using quantum information encoded on photons. In theory, QKD is proven secure. In practice, QKD systems deviate from this theoretical behaviour due to implementation.  Currently, QKD requires a separate dark fibre due to its susceptibility to classical channel effects (e.g., noise, Kerr non-linear interference, and scattering effects). Separating QKD from classical optical signals is costly and impractical, keeping QKD a niche product. Therefore, network providers seek quantum security to coexist in existing classical optical infrastructure. A better understanding of a quantum/classical optical channel is needed to develop improved channel coding, robust error-correcting schemes, digital signal processing, and optoelectronic components for the transceivers. In addition, a study on network topologies and integrating classical to quantum signals on implementation security is needed. The doctoral research network - QuNEST aims to gather diverse industrial and academic partners with strong scientific and technical expertise in QKD technology and optical communications to establish a new, innovative, multi-disciplinary, training network for doctoral researchers (DR). With the high-level objective of training experts to design, develop, and drive the future quantum secure optical infrastructure forward. This doctoral network will train 11 DR fellows, leaning on the expertise of 17 partners: 6 universities, and 11 Industrial partners (i.e., 1 Simulation software provider, 2 Telec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Legume-cereal intercropping for sustainable agriculture across Europe' (LEGUMINOSE) targeting Horizon Europe.

assistant: **Abstract**

As conventional cropping systems face deterioration of soil quality, loss of biodiversity, and declining ecosystem services, there is an urgent need to change practices to more sustainable yet productive systems. Intercropping enhances biodiversity, maximizes land productivity, and optimizes biogeochemical cycles in agroecosystems, but is lacking acceptance from European farmers. Legume-based intercropping takes advantage of biological diversity and synergistic effects between companion plants while reducing external inputs. A major objective of LEGUMINOSE is to identify the obstacles to intercropping and enhance farmers’ acceptance by providing knowledge and demonstrations that promote economic, environmental, and social benefits of legume-cereal intercropping. LEGUMINOSE will assess intercropping potential by focusing on pesticide reduction, plant-microbe mediated element cycling, soil health improvement, and crop quality and health. To overcome barriers to intercropping implementation, we will establish a network of six field trials and farm labs (20 farms in each country; 180 on-farm trials)  in different pedo-climatic zones across Europe (IT, DE, DR, ES, PL, CZ, UK), Egypt, and Pakistan. Furthermore, we will integrate remote sensing and crop modelling to survey fields, upscale the field-scale results, and create a web-based decision support system on intercropping. In collaboration with various stakeholders, legume-intercropping systems' economical, ecological, and social gains will be assessed and disseminated with international outreach from farm-level to policymakers. We will recognize and involve the whole value chain to explore and test innovative marketing strategies for the products of intercropping. LEGUMINOSE will contribute to the ecological intensificati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'KerecisTM Omega3 Wound: the first fish skin substitute in the European Market for chronic wound care' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Chronic wounds in general and diabetic foot ulcers (DFU) in particular are a challenge to wound care specialists and health care systems. With 8.5% of the global population suffering from diabetes, diabetic foot disease results in costs of about €4.1bn yearly in Europe alone. Patients find their quality of life seriously affected and, in many cases, DFU leads to amputation. Standard treatment for chronic wounds today is moist wound healing with standard wound dressings. Lately, efforts have been made to introduce novel, advanced treatment options, such as skin grafts from mammalian tissue and growth factors. However, none of these has been able to provide solid evidence for clinical efficacy and cost-effectiveness, and they are not available through public health care systems in Europe.Kerecis (Iceland), the coordinator of the Kerefish project, has developed KerecisTM Omega3 Wound, a novel skin substitute derived from North Atlantic cod skin. The unique structure of the grafts and their high content of Omega 3 fatty acids promote wound healing, even in severe DFU cases. KerecisTM Omega3 Wound has received the CE mark and FDA approval. However, as it is currently not reimbursed by public health systems in Europe, it is not yet available for the European population.Kerecis has teamed up with CERITD (France), an association for diabetes prevention and treatment and Endospin (Italy), a distributor of wound care products with experience in clinical trial sponsoring, to carry out large-scale clinical trials in 4 European countries and prepare the path to reimbursement and to the European health care market for this disruptive product, which will improve patients quality of life and help solve one of the pressing health problems of today’s societies.The Kerefish project will a