RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Receptor-Focused Interventions Against Orthoflavivirus Neuroinvasion and Entry' (REFINE) under Horizon Europe.

assistant: **Objectives**

REFINE confronts the escalating challenge of mosquito-borne orthoflavivirus infections, focusing on West Nile and Usutu viruses as emergent threats to European public health. The overall goal is to identify novel targets for therapeutics and to deliver a suite of validated models to assess efficacy and safety of novel compounds (antibodies, inhibitors, and vaccine candidate targets) for Phase I clinical trials. In the first of its six experimental objectives, REFINE characterizes genomic diversity of orthoflaviviruses to select representative clinically relevant strains. A unique strength of the proposal is the extensive suite of model assays (objective 2) designed to unravel the complex dynamics of virus-host interactions at each step of the infection pathway. These assays form a basis for receptor and pathway characterisation (objective 3). Objective 4 aims to asses both efficacy and safety of novel intervention strategies targeting these receptors and pathways, based on nanobodies, peptides and monoclonal antibodies. Objective 5 studies the key infection steps and putative receptors in humans, utilizing previously collected patient samples to ensure real-world applicability of developed strategies. Ultimately, objective 6 is to integrate knowledge gained to establish a robust and sustainable platform capable of rapid validation of new therapeutic interventions. The overall mission of REFINE is to significantly enhance Europe's preparedness and response abilities against the expected wave of mosquito-borne viral diseases. The team members share a lifelong commitment to advancing our understanding of the molecular mechanisms underlying various aspects of host-pathogen interactions at the human-animal-environment interface. Together, the REFINE team embodies a comprehen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Multi initiatives for rationalised accessibility and clean, liveable environments' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

There is a need to act locally both to improve urban quality of life and to contribute to resolving global problems of pollution and oil dependence. The MIRACLE sites respond to this challenge with measures that:1. Provide effective co-ordination between the demonstration sites and the networks coming from the accompanying measures for evaluation and dissemination to be established by the Commission;2. Develop and demonstrate the introduction of radical integrated sustainable urban transport policy strategies, supported by innovative technological infrastructures in real urban situations with large-scale application of innovative technology.For this, measures need to be organised into implementable groups of actions (ie: it is neither practical nor innovative to implement 7 measures and then evaluate each one).Goals are investigated by actions for defined demonstrations areas.There are 4 proposed goals:G1. A significant reduction in emissionsG2. Up-take of targeted types of clean vehicles (esp. electric scooters)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Unleashing gaze: Neuro-cognitive processes underlying gaze control and perception across free-viewing eye movements' (FREE-VIEW).

assistant: **Concept**

We constantly move our eyes to explore our surroundings. In between short periods of fixation, saccades cause drastic changes to the visual input – yet, we experience a continuous and stable world from the incessant flow of snapshots. While the perceptual consequences of saccadic eye movements are manifold, experiments to study them are surprisingly similar, and lean towards a paradoxically passive investigation of active visual perception. Instead of isolated, stereotyped eye movements directed by artificial cues, everyday gaze is dynamically driven by scene statistics and internal goals. To genuinely understand active perception across eye movements, we need to study it under natural but still precisely controlled conditions – which so far has been hindered by methodological limitations: the transient nature of peri-saccadic phenomena requires real-time knowledge of the upcoming saccade to tailor the perceptual measurement to its predicted spatial and temporal dynamics.Fortunately, free-viewing saccades are not random, but guided by salient and relevant scene features. My team and I will introduce a methodology that evaluates these factors online, to predict saccades during free exploration on dynamic visual noise. To study active perception through gaze-contingent measures across unconstrained viewing, my approach integrates high-precision yet rigid techniques from classic vision science with more flexible but coarser methods of scene viewing research, where subtle peri-saccadic processes are traditionally not considered.Combining state-of-the-art psychophysical, computational, and neuroscientific expertise, FREE-VIEW will pioneer our understanding of actually active perception and gaze control, assess the validity of inferences drawn from atypical, instructed saccad
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Integrated innovative pilot system for Critical Raw Materials recovery from mines wastes in a circular economy context'.

assistant: **Concept**

RAWMINA will develop and demonstrate an innovative pilot system for the clean and sustainable production of non-energy, non-agricultural raw materials (RMs) in the EU from Mine Waste (MW) resources. RAWMINA will implement and standardize an innovative energy, water- and cost-effective continuous pilot process for producing RMs. It will integrate novel bio-leaching and nano-based materials for Sb, Co, Ge and W selective recovery from MW from “unexploited/underexploited metal containing materials”. RAWMINA will improve EU competitiveness and create added value in RMs processing, refining and equipment manufacturing by developing a new circular business model as an alternative to traditional linear mining economy. RAWMINA will integrate different technologies that will be demonstrated (TRL7) with MW of diverse geological compositions from EU and non-EU mines demonstrating flexibility in processing of the innovative pilot system. The project will perform a techno-economic and sustainability assessment throughout the entire life cycle considering health, safety, socio-economic and environmental impacts; maximizing water/energy efficiency and waste/wastewater reduction. IP, exploitation and business plans will be developed ensuring market penetration, technology export and first exploitation plan. RAWMINA will transform MW into a resource, enabling marketable products recovery to be used in batteries, flame retardants, optical fibers and industrial tools. The project will create a CRM Recovery Helix to maximise clustering and will interact with local communities to gain EU citizens trust. It will increase resource efficiency and sustainability of EU industry, contributing to decrease EU CRM import dependency. Apart from sheltering the EU from possible shortages in CRM supply,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Iran and British Muslims: A Study of State-Sponsored Religious and Political Transnationalism' (2007-2013) under Seventh Framework.

assistant: **Objectives**

This research examines the religious and political ties between 'official' Iran and UK-based Muslim communities. Based on a case study of Iran's institutional presence in the UK that will discuss its multifaceted religious, educational, and political programmes for coreligionists, it seeks to analyse how the Islamic Republic transfers, negotiates, and reformulates its norms and values transnationally. The British scene offers an interesting case study primarily because it is host to many Sunni and Shi‘i Muslims from different ethnic and national backgrounds, communities to which the Islamic Republic of Iran has paid particular attention from the 1980s onwards.Looking specifically at the effect of transnationalism on the state, this research will analyse the Islamic Republic’s use of cross-border activism as a soft power resource. In general terms, Iran’s transnational interactions with Muslim communities have mainly been studied with regard to Islamic political movements in Arab and Central Asian countries, while its reach to coreligionists living away from their country of origin has largely been overlooked in the literature.Yet, Iran’s involvement in the lives of Muslim migrants, refugees, and exiles is characteristic of its quest for religious and political leadership outside the country’s borders and, I argue, has much to say about the use of religion to advance state interests. As such, the benefits of state-sponsored transnationalism cannot only consider the direct ties Iran creates and maintains with Muslim believers, but also its relations with both their country of origin and the state hosting them (namely the UK), as well as with other transnational actors involved in transnational activities on the British scene.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'A Collaborative Mobile Robot Arm that can Learn Impedance Critical Tasks from Humans' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The aim of the proposed research is to develop a mobile manipulator that can effectively learn impedance critical tasks by means of physical interactions with a human, and acquire human’s abilities via human-to-robot skill transfer for subsequent autonomous task execution.  In a factory environment, execution of such tasks, e.g., drilling, screwing, are frequently encountered and can be easily accomplished by human workers. Nevertheless, automating these tasks with robots require expert robotics engineering knowledge, robot-specific arrangements in the factory, and exact model of the environment. Through the integration of human-to-robot skill transfer techniques, these monotonous tasks can be autonomously handled by a mobile manipulator so that human workers can focus on more complicated tasks. To this end, this project aims to develop required technologies to create such a system that can be actively used in a real factory environment for actual scenarios. With the successful completion of the project, a crucial building block will be built for human-centered robotic automation, which is of importance in keeping the manufacturing jobs in EU.Upon the completion of the project, it is anticipated that an invaluable robotic platform that corresponds to Industry 4.0 criteria will be obtained. Due to nature of the project, the system will be a patented end-product for industrial manufacturing tasks. Therefore, it will lead to a strong university-industry collaboration which will be greatly benefited by the host institute, OzU, and the researcher. Moreover, the project will greatly expand the research network for the researcher as he aims to be a leader in the field and expand his research expertise with this multidisciplinary project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Deciphering the machinery involved in stability of the transcription factor HOXA9.' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

Transcription factors are often mutated or aberrantly expressed in cancer and drive carcinogenesis. HOXA9 is a master transcription factor that controls a network of genes critical for hematopoiesis. It shows increased expression levels in more than 50% of patients with acute myeloid leukemia (AML), and is strongly associated with poor clinical outcome. Since the initiation and progression of AML depend on elevated HOXA9 levels, it represents an attractive therapeutic target to combat this aggressive malignancy. However, transcription factors are often not amenable to direct pharmacologic inhibition. To overcome this limitation, an alternative strategy aiming at interference with the transcription factor-specific 'degradome' - the degradation machinery regulates HOXA9 stability. To this end, we aim to elucidate the HOXA9 degradome with the goal of identifying its druggable nodes. Specifically, we plan to (1) identify regulatory proteins involved in the degradation of HOXA9 by performing a FACS-based positive selection screen with a focused CRISPR/Cas9 library as perturbation tool, (2) validate candidate proteins involved in the control of HOXA9 stability, and (3) characterize hits suitable for pharmacologic targeting. For the most promising HOXA9 regulators, we will determine their specificity by assessing global changes of protein abundance by proteomics. The potential of employing hits for pharmaceutical targeting will be evaluated by integrating molecular information with clinical data.In summary, this project aims to establish novel strategies for the dissection of the transcription factor HOXA9 degradome by developing a flexible screening platform. Through this project, I will not only acquire new skills but also establish a scientific network, which is expected to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'IMPLANTATION IN A PILOT SCALE OF A NEW ORGANISATION FOR HOT DIP GALVANIZATION INDUSTRIES' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Today in Europe, a galvanisation workshop can have annual cost of waste treatment from 40 000 to 120 000 Euro depending on the size of the industry and the country. All galvanisation workshops are confronted with the problem of elimination of pickling bath chemicals. The valorisation of these baths presents the most favourable solution.The aim of the project was the pilot scale implementation of a new process in hot dip galvanisation workshops in order to demonstrate its efficiency and technical-economical viability, according to the earlier successful results of a CRAFT project. This project looked at the environmental problems of this industry through waste minimisation and proposed a clean technology compared to the traditional solutions.The objectives of the project were to:- improve the pickling process, introduce new concepts such as stirring and temperature control and optimise the management of the baths.- avoid the cross contamination of Zn and Fe in both the pickling and the etching baths.- produce valorizable wastes with the following characteristics: a bigger concentration of the metals iron and zinc in the bath; and no contamination of iron in the bath of zinc and vice versa.The final result of the project were an optimised process based on existing pickling procedures. Most of the existing facilities and infrastructure in the hot dip galvanisation workshops could be used and some modifications will be needed. The final process will be based mainly on methodology and good practice without interference in the organisation and in the good quality of the galvanised materials being produced.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Cost-Effective Tools for Better Indoor Environment in Retrofitted Energy Efficient Buildings'.

assistant: **Innovation**

The refurbishing to an energy efficient standard leads to tight buildings (whole envelope: windows, walls, etc.) and affects the indoor climate. In case of refurbishing the inhabitants or users are not adapted to this new situation. Therefore the air exchange rates could be lower than required if no mechanical ventilation is installed or the system performance is not optimised. Then, in trying to increase the energy performance of buildings, the indoor environment quality is often degraded due to the lack of exchange with the outdoor environment.People in Europe spend more than 90 % of their time indoors (living, working, and transportation). In more than 40 % of the enclosed spaces, people suffer from health- and comfortable related complains and illness. Already in 1984 the WHO reported an “increased frequency in buildings with indoor climate problems”. The complexity of the problem and the fact of building related symptom clusters were later described as “Sick Building Syndrome”.The main objective of the project is to develop innovative solutions for better monitoring the indoor environment quality and to investigate active and passive systems for improving it. The focus lies on cost-effective solutions to ensure a wide application of the developed systems. The project is based on three main objectives:- Development of monitoring systems (wireless and/or partly wired) to detect insufficient comfort and health parameter. It is foreseen to develop a modular version for allowing normal end users making a quick check of the indoor air quality.- Development of control systems for indoor environments which could be based on passive elements like cost effective photo catalytic materials or PCMs and active systems which control the air flow rates based on the monitoring data
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Non perturbative dynamics of superstring theory' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

In the last year, the strong coupling behaviour of many supersymmetric string theories has been determined. This is very important because for the first time there are concrete indications on how superstring theory should be formulated beyond perturbation theory. However, there are several problems which need to be solved, and this is the aim of this project. In particular, superstring theories contain an infinite tower of stable (BPS) states in the perturbative spectrum, and they must exist nonperturbatively as solitons in the dual theories. Understanding the general class of exact solutions of low-energy supergravity corresponding to these states will have important implications for string dualities and, in addition, it will clarify the statistical origin of the entropy of supersymmetric black holes. The second objective of the project is to investigate the relation of string theory to eleven dimensions. This project is expected to provide results of high relevance for revealing the non-perturbative aspects of superstring dynamics.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Enhanced transnational access to abisko scientific research station (ANS)' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Nabisco Scientific Research Station is located in one of Europe's last remaining wilderness area. The station is operated year-round in a sub arctic environment; it is well equipped with lab- and field equipment for bio- and geo-scientific investigations. The station can accommodate almost 100 scientists in comfortable rooms and apartments in immediate closeness to study areas. From the station a unique possibility to reach a range of environments exists. Nabisco is easily reached throughout the year by air, train, car or bus.The station was established in the beginning of the 20th century and has beside a unique scientific documentation of the surroundings in terms of more then 2500 publications, also an existing long record of several environmental data. This gives the users of the station important background information on the environment surrounding the station. The station is internationally well known, and is visited by approximately 700 visiting scientists yearly. The station will during the suggested 4-year period be able to offer 4100 man-days for 140 scientists.