RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Rapid evolutionary responses to climate change in natural populations: Integrating molecular genetics, climate predictions and demography into an eco-evolutionary modelling framework' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Intensification and increased frequency of weather extremes is emerging as one of the most dramatic aspects of climate change. Thus, the study of ecological implications of global-scale changes is expanding from a focus on trends (e.g., mean temperatures)  to broader investigations including the effects of extreme events and associated catastrophic disturbances (e.g., floods, fires, droughts). However, investigations  exploring adaptations of individuals and species to altered patterns of extreme events are still rare and overarching studies are greatly needed. Crucially, rapid evolutionary and adaptative processes are highly relevant for understanding and predicting species responses to climate change. I propose to investigate the selective consequences of periodic catastrophic disturbances on genetic diversity and life-history traits, using marble trout (Salmo marmoratus) populations living in Slovenian streams as a model system.  In this system, flash floods and debris flows causing massive fish mortalities are increasing in frequency and intensity.I will use an innovative multidisciplinary and interdisciplinary approach, combining (i) molecular genetics, (ii) demographic analysis and statistical characterization of temporal and spatial patterns of flood events, and (iii) life-history, demographic and eco-evolutionary modelling, to understand and predict the selective consequences of the altered pattern of catastrophic disturbances on the genetic composition and life-history traits of marble trout.Bringing together genetic, climatic, life-history and demographic aspects in this model system will allow the development of an overarching and general modelling and conservation framework for  rapid evolutionary and adaptive processes, and will establish a reference of how
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Developing Innovative Market Orientated Prediction Toolbox to Strengthen the Economic Sustainability and Competitiveness of European Seafood on Local and Global markets' in the context of a Horizon 2020 call.

assistant: **Objectives**

The overall aim of PrimeFish is to improve the economic sustainability of European fisheries and aquaculture sectors. PrimeFish will gather data from individual production companies, industry and sales organisations, consumers and public sources. The data will be related to the competitiveness and economic performance of companies in the sector; this includes data on price development, supply chain relations, markets, consumer behaviour and successful product innovation. The large industry reference group will facilitate access to data on specific case studies. A data repository will be created, and PrimeFish will join the H2020 Open Research Data Pilot to ensure future open access to the data. The effectiveness of demand stimulation through health, label and certification claims will be evaluated and compared with actual consumer behaviour. PrimeFish will assess the non-market value associated with aquaculture and captured fisheries as well as the effectiveness of regulatory systems and thereby provide the basis for improved societal decision making in the future. The collected data will be used to verify models and develop prediction algorithms that will be implemented into a computerized decision support system (PrimeDSS). The PrimeDSS, together with the underlying data, models, algorithms, assumptions and accompanying user instructions will form the PrimeFish Decision Support Framework (PrimeDSF).The lead users, typically fishermen, aquaculture producers and production companies, will be able to use the PrimeDSF to improve understanding of the functioning of their markets and in setting strategic plans for future production and innovation which in turn will strengthen the long term viability of the European fisheries and aquaculture sectors. This will also benefit c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Virtual Centre' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

PJ32-W3-01 Virtual Centre - Complement of PJ10-W2-93 Delegation of airspace amongst Air Traffic Service Units (ATSUs). While PJ10 W2-93 addresses the ATC aspects of airspace delegation amongst ATSUs, this solution will further investigate the Air Traffic Flow and Capacity Management (ATFCM) aspects of such airspace delegation amongst ATSUs. This proposal addresses also the need to develop the technical infrastructure to support the validation activities planned by SESAR2020 Wave 2 solution PJ10-W2-93 on the ATC aspects of airspace delegation amongst ATSUs and the validation activities required on the ATFCM aspects of airspace delegation amongst ATSUs.


**Keywords:** Virtual Centre, Airspace Delegation, Air Traffic Service Unit, ATM Data Service provider, virtualisation, de-fragmentation, digitalisation, intertoperability,  Airspace Architecture Study, SESAR
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Driving agroecological transitions in the humid tropics of Central and Eastern Africa through traNsdisciplinary Agroecology Living LabS (CANALLS)' (CANALLS) targeting Horizon Europe.

assistant: **Abstract**

The humid tropics of Central and Eastern Africa hold much promise for enhancing food and nutritional security within and beyond Africa. With a rich variety of agroecological zones and diverse farming systems, they are home for a great part of the rural population and a large diversity of living organisms, offering vital ecosystem services and potential for sustainable development. Still, if we are to tap into this potential, we need to address the complex environmental, social and economic challenges they face, which in cases are exacerbated by conflict and high vulnerability. In this context, CANALLS aims to drive agroecological transitions in the humid tropics of Central and Eastern Africa via multi-actor transdisciplinary Agroecology Living Labs (ALLs). We start with 8 ALLs in DRC, Burundi, Cameroon and Rwanda, working alongside and enabling over 20,000 farmers and value chain actors to co-create and benefit from optimal combinations of agroecological practices focusing on crops that are vital for subsistence and economic development (cocoa, coffee, cassava, rice, maize). In parallel, we engage in solid multi-actor collaboration with rural communities, advisory services and governments to develop a holistic assessment framework and evaluate the socio-economic and environmental performance of the co-created practices (accounting for trade-offs and synergies). We use the comprehensive evidence generated to build capacity and share knowledge (practice abstracts, replication guidelines, policy recommendations) as well as to deliver fair, inclusive and sustainable business models along with services and tools for facilitating access to markets and enhancing demand for agroecological products. Our vision is to create a growing network of ALLs that leverages EU-AU cooperati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Identifying the Needs for Patients Partnering in Clinical Research' (PATIENTPARTNER) targeting Seventh Framework.

assistant: **Abstract**

The aim of this 3-year Coordination Action will be to identify the patients’ needs for partnership in the clinical trials context. Moreover, this project will lead to both a well-organized and sustainable communication platform and guidelines to enable the mutual beneficial interactions between patients and clinical trials professionals. This aim will be realized through: I) Interviews, addressing patients (-organizations) that will identify preliminary needs in the clinical trials context from a patients’ perspective. These data are complemented with literature reviews and descriptions of best practices. The combined outcomes will be accessable on a centralized webbased database. II) Subsequent workshops addressing patients (and patient organizations), researchers and scientists, biopharmaceutical companies, regulators and other stakeholders in the clinical trials context. In these workshops, the conclusions from the interviews, literature studies and best practices will be challenged to draw ‘European’ viewpoints and consensus. On the specific website, attendees will be able to consult the outcomes from both the investigational phase and previous workshops. III) The establishment of the European Network of Patients partnering for Clinical Research (EN-PCR). Initially, EN-PCR will be responsible for addressing the high priority issues in this project: paediatric clinical trials, patient registries and biobanks, the Innovative Medicines Initiative (IMI) and ethical issues. Later on, EN-PCR will guarantee the sustainability of this project, being a permanent structure with a bi-directional purpose, both empowering patients and functioning as a one-stop shop for academic and biopharmaceutical research. IV) Further dissemination of the project results will be achieved by a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Unravelling environmental exposures  in the core axis of ageing' under Seventh Framework.

assistant: **Concept**

AGEing is a complex phenotype responsive to a plethora of ENVIRONmental inputs (ENVIRONAGE). Age related conditions in adults often find their origin in risk factors operative in early life. The molecular mechanisms behind these phenomena remain largely unknown. Mitochondria are involved in a variety of critical cell functions, including oxidative energy production and programmed cell death. Recently, I established in a study of 175 newborns, a strong association between mitochondrial DNA content and in utero exposure to particulate air pollution. Telomere length is highly heritable and erosion leads to an increasingly vulnerable structural integrity of the chromosomes. It is considered a marker of overall biological age compared with chronological age. In this regard, I demonstrated the heritability of telomere length and the influence of smoking on telomere erosion. These results support the ENVIRONAGE hypothesis, i.e. that environmental inputs influence biomolecular markers of ageing including mitochondrial function, telomere length along with DNA repair and epigenetics as the ‘core axis of ageing’. The aim is to establish prospective epidemiological evidence for molecular mechanisms or early biomarkers, which may underlie the origins or reflect the risk of age-related diseases and to understand its association with other processes and the influence of environmental factors. To this end, I will establish a birth cohort and a cohort in middle-aged and elderly. I measure environmental pollutants, in interaction with parameters that I consider to have an important role in the ageing process (mitochondrial function, telomere length, epigenetics and DNA repair capacity). ENVIRONAGE integrates environmental influences and molecular mechanisms on ageing. The common molecula
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Oxygen Activation in Ribonucleotide Reductase and Multicopper Oxidases Proteins' to be submitted under Seventh Framework.

assistant: **Abstract**

Boundaries among biological, chemical and physical domains are nowadays fading, and the complex phenomena observed in Nature as well as in artificial systems can only be tackled from a broader/interdisciplinary perspective. In this context, the biological activation of the molecular oxygen is a fascinating and yet complex process. The ability to store, transport and utilize this simple molecule gated evolution of life in our planet and led to growth and selection of a variety of organisms. Complex molecules selected by Nature as active in “key metabolic paths” of the oxygen in life often contain copper and/or iron metal ions as reactive centres. A wide variety of experimental results and theoretical investigations show that the metallo-oxygen interactions have dominant states that are not spatially homogeneous (anisotropy). These effects occur when a number of physical interactions such as spin, charge, lattice (crystal-field), and/or orbitals are simultaneously active. The result of these interlocked numbers of factors links biology to chemistry and molecular physic, and allow the oxygen to be used in different ways within metabolism. The research proposal presented herein aims to investigate the red/ox mechanism and the connected energetic of the oxygen activation process in a series of di-iron (Ribonucleotide Reductase, RNR, Class I R2) and copper protein (multicopper oxidases) through the use of spectroscopic methods (EPR X-Q, high field EPR, CD, MCD, rR resonance Raman), structural (X-ray) and kinetic analyses (stopped flow, cryoenzymology). The endeavour is directed towards a better understanding of the geometric and electronic structure of metal-oxygen interactions that contribute to define O2 reactivity. These studies will provide molecular level insight into ox
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Biology of Neuro-degenerative Diseases Research' (BIND) targeting Sixth Framework.

assistant: **Abstract**

The Kuopio University campus in Finland hosts about 20 neuroscience groups and 50 PhD students in 5 graduate schools. The 2 major basic science facilities (A.I. Virtanen Institute for Molecular Sciences and Department of Neuroscience and Neurology) are located near the Department of Neurology in Kuopio University Hospital. Our feature worldwide is a strong continuum between basic and clinical research that takes questions from lab-bench to bedside and back. The major research interests include studies on 3 neuro-degenerative diseases, that is, Alzheimer's disease, epilepsy, and stroke. Kuopio neuroscience community has established an active research collaboration in the biology of neuro-degeneration and training of postdoctoral fellows and PhD-students. In t his project, 5 senior investigators join their expertise to facilitate and capitalize the benefits of synergy in methodology, infrastructure, data sharing, and research training.We have 4 major research goals during 2006-2010 in understanding neuro-degenerative diseases:(1) identification of novel molecular pathways mediating neuro-degeneration and repair(2) development of novel in vitro and in vivo models of human neuro-degenerative diseases,(3) identification of surrogate markers that predict the neurode generative process and its outcome, and(4) identification novel gene mutations linked to human neuro-degenerative diseases and their function in the neuro-degenerative process.We have established training program including 2-3 courses, seminar series, summer schools, international conferences annually, as well as weekly laboratory meetings and day-to-day personal supervising. We aim at continuing scientific excellence and providing first-class training for our PhD students and post-docs, serving as a source of exp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Systematic studies at the ams-facility at Naples for chronological dating with high precision' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Research objectives and content The technique of Accelerator Mass Spectroscopy (AMS) allows dating geological and archaeological materials with high precision (so called C14-method). The AMS-facility at Naples is in operation since many years, particularly for investigations . on the chronology of volcanic eruptions. However, precise data on the chronology of historical volcanic eruptions in . Campania are still needed. Furthermore no investigations on the time needed for the re-establishment of environmental . conditions allowing human re-settlement in sites interested by catastrophic eruptions have been performed up to now, although the AMS-technology allows to extract data with highly improved precision. The investigations mentioned above can not be performed using the AMS-system presently available at Naples: These studies demand for improved precision of the analyses as well as for higher throughput of samples to allow systematic studies. Significant technical improvements, i.e. implementation of a dedicated injection system and a fast cycling system, have to be made at the AMS-facility in order to meet these demands. The operation of the new injection system allows to optimise the AMS-system not only for the C14-method but also for different isotopes, such as 10Be and 26A1. The use of these isotopes in the Naples-AMS-facility may demonstrate the potential of AMS in a wide range of different research fields and applications. The research project aims at the technical improvement of the AMS-system at Naples. The applicant will invest his expertise on high voltage techniques and accelerator technology gained in university and industrial projects to implement these improvements under a definite time schedule and a duration of 1 year. Furthermore, systematic studies on
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'What drives human behavior regarding global coastal migration and adaptation in response to sea level rise and extreme flood events?' (COASTMOVE).

assistant: **Innovation**

Future sea level rise (SLR), extreme flood events, and urbanization pressure will increase coastal flood risk, and in the absence of costly flood protection measures in numerous regions, millions of coastal residents will be forced to migrate to safer locations. This research addresses the significant challenge these trends pose to adaptation and migration policy: Which coastal areas will be protected, and in which regions will coastal migration become the inevitable adaptation option?To tackle this challenge, I propose focusing on the human adaptive and migration behavior of residents and other agents within one global framework by integrating (1) a global coastal flood risk model with (2) an agent-based model (ABM). Current global coastal risk assessment and migration methods do not address individuals dynamic decisions regarding SLR and extreme flood events, and instead assume their adaptive behavior remains constant. However, the drivers that motivate people to migrate and adapt vary over time and space, and to capture these drivers (3) empirical data will be collected across seven surveys to parametrize realistic ranges for the behavioral rules in the ABM. (4) Novel global databases on flood protection, demography and socio-economy will be developed to extrapolate behavioral rules from the cases to other coastal areas. (5) State-of-the-art big-data methods using Twitter, mobile phone and IRS tax-filing data will be used to calibrate and validate migration patterns simulated by the global framework.The framework offers several advantages: high resolution (1x1km2) global migration, adaptation, and risk projections (20202100); novel maps of future migration hotspots; an improved understanding of what drivers (environmental, socio-economic, demographic, etc.) and inter
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Multimedia COntents and Tools for adaptive SCalable Interfaces' (MOTICS).

assistant: **Innovation**

Although Europe as a whole possesses the richest artistic patrimony in the world, business-oriented services based on the most advanced Information Technology and Communication (ITC) are not widely used in this field. This huge amount of information has a straightforward, potential exploitation in the electronic market.The main objective of MOTICS is to bridge the gap between the availability of cultural heritage contents and their exploitation by means of state-of-the-art technological solutions. The basic concept developed in MOTICS is that of adaptive and scalable interfaces, in terms of interactions paradigms, access to the network and multimedia contents. MOTICS will interpret the user's request, select and collect the proper data from the content repositories, and arrange them into a preformatted scenario (the interface) according to the user's profile.