RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Modelling brain aneurysm to elucidate the role of platelets'.

assistant: **Innovation**

In the European Union, 15 million people have an unruptured intracranial aneurysm (IA) that may rupture one day and lead to subarachnoid haemorrhage (SAH). The IA rupture event is ominous and lingers as a clinical quandary. No safe and effective non-invasive therapies have, as of yet, been identified and implemented in clinical practice mainly because of a lack of knowledge of the underlying mechanisms. Increasing evidence points to inflammation as one of the leading factors in the pathogenesis of IA. Intrasaccular clot formation is a common feature of IA occurring unruptured and ruptured IA. In addition to forming clots, activated platelets support leukocyte recruitment. Interestingly, platelets also prevent local hemorrhage in inflammatory situations independently of their ability to form a platelet plug. We hypothesize that the role of platelet may evolve throughout the development of IA: initially playing a protective role of in the maintenance of vascular integrity in response to inflammation and contributing later to intrasaccular thrombus formation. What are the platelet signaling pathways and responses involved and to what extent do they contribute to the disease and the rupture event?To answer these questions, we designed an interdisciplinary proposal, which gathers biophysical, pharmacological, and in-vivo approaches, with the following objectives: I) To investigate platelet functions from patients diagnosed with intracranial aneurysm at the sites of aneurysm sac. II) To delineate platelet mechanisms and responses in a cutting-edge technology of a 3D reconstruction of IA that will take into account the hemodynamic shear stress. III) To test in a preclinical mouse model of IA efficient anti-platelet therapies and define a therapeutic window to intervene on plat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Affordable photonic-chip based optical nanoscopy'.

assistant: **Objectives**

The invention of super-resolution optical microscopy, commonly referred to as optical nanoscopy, has provided a glimpse of future impacts on cell-biology and health. Imagine the possibilities of scientific discoveries if every research and clinical lab is equipped with an optical nanoscope that is capable of imaging with resolution of sub-50 nm. Even though nanoscopy offers unprecedented opportunities, the widespread adoption of present nanoscopy is limited due to its present limitations, mainly system complexity and high ownership cost, next to technical limitations such as low throughput, slow-imaging speeds and lack of multi-modality.In the ERC PoC project, I will develop user-friendly photonic chip-based nanoscopy, to be used in a standard microscope, where sample is placed on top of a photonic chip capable of both holding and illuminating the sample, enabling to acquire super resolved images. Photonic-chips together with coupling unit can be retrofitted to any existing standard microscope converting it to high-resolution optical nanoscope.


**Keywords:** Super-resolution microscopy, bio-imaging, integrated optics
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'How Play Shaped the United States from New Media to Politics: Worlding America, 1503-2028' (WORLDING-AMERICA), addressing dissemination and exploitation.

assistant: **Impact**

WORLDING AMERICA researches how “play” has been a key force in the past and present process of creating America as a coherent and hegemonic “world,” from 1503 to the present. Play is an activity linked to change, serious even when frivolous, potentially transgressive even when rule-bound. Play intersects with the process of worlding (bringing a new world into existence) in liminal moments. In such unstable phases, when new worlds take shape, but are not yet consolidated, play comes to the fore as a way to probe possibilities.I seek out such historical moments of disruptive play when a new visual medium was introduced that contributed directly to tangible political change. I study four pivotal cases: Worlding Colonial America through Engravings, 1590-1776; Worlding the Nation through Newspaper Cartoons, 1870-1924; Worlding the Body Politic through Television, 1972-2022; Worlding Colonial Mars through Twitter/X, 2006-2028. Tracing specific elements of play, in particular imagination, invitation, participation, and improvisation, across cases, I demonstrate how forms of play have been essential to American worlding in ever evolving mediascapes. I hypothesize that play has intensified through the rise of social media, to such an extent that current forms of worlding driven by play have overridden traditional rules of politics, thus changing the game while playing it.I employ source-based qualitative methods from cultural history, media studies, and American studies to synthesize these cases of hegemonic playful worlding, into a comparative transhistorical framework. I move beyond American grand narratives so as to understand the role of play in their construction and implementation, thus contributing an innovative dimension to the composite field of American Studies. Additi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Intersectional Analyses of Welfare Chauvinism in Europe' (INWELCHAV), addressing dissemination and exploitation.

assistant: **Impact**

In the European context of ongoing crises (economical, political and humanitarian), populist radical right parties have consolidated their presence in mainstream politics. These parties sharpened the debate concerning the future of the welfare state, arguing for a separation between the “natives” of the ethnic majority, as self-evident targets for full welfare provision, and those belonging to a generic “other”–wherein migrants, ethnic minorities, racialized groups, people with alternative lifestyles are lumped together. However, both studies of the populist radical right and welfare studies are missing an intersectional awareness to how such conceptual distinction is operated. Taking a decidedly interdisciplinary approach, the present project aims to explore and scrutinize in a comparative framework the populist radical right’s discursive (re)construction of cultural identities and the terms of national belonging at times of economic, political and societal crises across Europe, from an intersectional perspective. The project will combine political sociology, with a focus on welfare and populism studies, intersectionality, and critical discourse analysis. The project focuses on three cases: the Finns Party (PS/SF) in Finland, the Greater Romania Party (PRM) in Romania, and the Sweden Democrats in Sweden. The objectives are to provide an account of the communalities and differences in articulating national identity and welfare chauvinism in the chosen countries, and to map out how these are expressed within the common European institutional framework, namely in the European Parliament.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Reproductive isolation and competitive ability between native and non-native ranges of invasive weeds' (REPROWEED).

assistant: **Concept**

Over the last three centuries many species have been dispersed beyond their natural geographic limits by humans, but to our knowledge no reproductive isolation has been demonstrated for such neo-allopatric species. Centaurea solstitialis and C. sulphurea have overlapping distributions in their native and non-native ranges. Our preliminary results show that seed production of Californian inflorescences of both species, treated with pollen from Spanish populations of the same species, was 52% and 44% lower, respectively, than inflorescences pollinated with Californian pollen, suggesting that rapid reproductive isolation may have occurred between native and non-native ranges.  Reproductive isolation between Californian and Spanish populations of C. solstitialis was 68% of the reproductive isolation for interspecific hybridization among these three species.  Considering the large numbers of neo-allopatric species our results are unlikely to be unique. We already have seeds from Turkey and Georgia, the geographical speciation origin of the species; Spain, the last native range before the colonization of the Americas; Chile, the first American country to be colonized; and California, where the species present the most agressive invasive behavior and higher densities. With these seeds, we plan to obtain an F1 free of maternal effects and to cross-pollinate them to detect levels of reproductive isolation either pre-existing or newly developed in the non-native ranges. We will study the type of incompatibility by means of the study of pollen growth. We also plan to conduct reciprocal transplant experiments in Spain and California to study plant behavior in natural conditions (biomass, pollinator attraction, flower and seed production, herbivory) and to calculate phenotypic plast
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Critical transitions and self-organization in sleep micro-architecture' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Humans and animals exhibit brief awakenings from sleep (arousals), which are traditionally viewed as random disruptions of sleep caused by external stimuli or pathologic perturbations. However, our recent findings show that arousals represent previously unrecognized intrinsic aspects of sleep, and exhibit complex temporal organization and scale-invariant behavior characterized by a power-law probability distribution for their durations. In contrast, sleep-stage durations exhibit exponential behavior. The co-existence of these two very different processes in the sleep regulatory mechanism has not been observed in any other physiological system, and resembles a special class of non-equilibrium physical systems exhibiting self-organized criticality (SOC). Such organization of arousals makes it unlikely that they are merely a response to random stimuli, however, the role arousals play in healthy sleep and in sleep disorders remains unknown.Since our preliminary analyses show that SOC-type dynamics persist throughout the sleep period in humans and across several mammalian species with different sleep architecture, we hypothesize that arousals are an integral part of healthy sleep and relate to basic neuronal interactions. To address this hypothesis we will combine human sleep data and bio-molecular/genetic animal experiments with modern approaches from statistical physics of non-equilibrium systems and the theory of complex networks. Our objective is to uncover basic principles of self-organization in sleep that would elucidate the interrelation between sleep-stage dynamics and arousals, and to derive novel and more sensitive diagnostic markers of sleep disorders.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Safety of Innovative Reactors Designs' to be submitted under Sixth Framework.

assistant: **Abstract**

Specific Objectives:1. To test the integrity and fission gas release of HTR fuel compacts provided by General Atomics;2. To test the integrity and fission gas release of HTR fuel pebbles provided by FZJ during irradiation in the HFR; to irradiate these pebbles to a high burn-up (for enabling subsequent accidental fission gas release tests in the KÜFA facility at JRC-ITU); to allow for simultaneous piggy-back testing of graphite specimens;3.1. To design, build, commission and test a new facility to carburise and decarburise test coupons; 3.2. To modify an existing facility for measuring the impact, tensile, creep, and fracture mechanics properties of: - surface-treated Ni superalloys (and possibly Ti or Mo base alloys or CFC or SiC/SiC composites) for HTR He turbines - HTR reactor pressure vessel material including thick welds on commercial P91 steel - carbon fiber composites (CFC) for HTR control rod clads;4. To pursue with HTR-TN partners the coordinated definition and execution of R&D;5. To review existing HFR fuel test reports and to develop a user- friendly interface for facilitating data entry in the fuel database;6. To contribute to the final definition of selection criteria for innovative reactors and fuel cycles in IAEA/INPRO;7. To modify certain computer codes (EAC2, STAR-CD) to make them suitable for use with the coolants lead and helium. To prepare reactivity worth curves with the neutronic code HEXNODYN. Accident initiators that will be investigated are unprotected Loss-of-Flow, Loss-of-Heat Sink, depressurisation- and reactivity-accidents as well as emergency decay heat removal; 8. To perform a feasibility study for a small-scale out-of-pile experiment to verify whether Pb or Pb-Bi will absorb Cs and I vapours. Anticipated milestones and schedule M1.1 HFR-E
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'EUROPEAN OPPORTUNITY MAPPING', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

EUROMAP is designed to conduct an analysis of national priorities and opportunities for future LE research and applications. The project brings together organisations acting as national 'focal points' from all EU/EEA countries. It will undertake to promote awareness about the potential of LE within industrial and government circles, improve synergy between LE and related national programmes, and to assess, and where possible bring closer together, national policies and frameworks in the LE area. As a result of the fieldwork to be undertaken in the participating countries, EUROMAP is expected to yield an informed view on relevant national research strands, industrial plans and expectations, and government initiatives. From this base of information, scenarios and 'opportunity maps' will be made, facilitating trans-national co-operation to the benefit of research, industry and public services. Awareness will be greatly enhanced through a series of 'national seminars' bringing together representatives from the sectors and groups targeted by the project.Europe currently faces a double challenge: how to maintain its rich linguistic diversity, and at the same time ensure that its businesses and citizens can participate fully in the information revolution. The EU Council, in its role as representative of the member states, has been especially forthcoming in support of the importance of language in this new context. The long-standing support of linguistic research by the European Commission, through a series of research initiatives culminating in the language research and engineering segments of the Third and Fourth Framework Programmes, have begun to yield results with practical, valuable potential for a multi-lingual European information society. Due to its linguistic diversit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Creating Knowledge'.

assistant: **Objectives**

In this project I want to unravel how we build-up and update our knowledge networks depending on the amount of previous experience we have by testing my new theory on experience dependent learning. Current theory postulates memories to be stored initially as sets of neural representations spanning the hippocampus and weakly interacting neocortical modules. The spontaneous reactivation of new memories during a consolidation phase, would lead to strengthening of the neocortical memory trace. Consequently, pre-existing knowledge is proposed to be coded in the brain as a cortical network of neurons that allows for more efficient consolidation of new information. I recently developed a new theory, proposing that the existence of previous knowledge and therefore the extent of the cortical memory network, is a gradient of experience instead of being either present or not. The size and complexity of the knowledge network would influence where in the brain memories are encoded and how fast they are consolidated. I propose combining my innovative behavioural paradigm  the HexMaze - that enables investigatory access to various levels of experience, with different techniques in three species to test this theory. In mice, with immediate early gene expression techniques to visualize and manipulate the brain-wide memory network with the resolution of individual neurons. In rats, with electrophysiology to measure and manipulate memory reactivations during sleep as the mechanisms to enable consolidation. In humans, with targeted memory reactivation and magnetic resonance imaging to follow the evolution of learning over one year. The combination of species with their respective methods enables to observe effects as well as test for causality. The unique combination of meaningful behaviou
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Engineering Apps for advanced Manufacturing Engineering' in the context of a Seventh Framework call.

assistant: **Objectives**

Manufacturing is being shaped by the paradigm shift from mass production to on demand dictated, personalised, customer-driven and knowledge-based proactive production. Thus, shorter product life cycles, an increased number of product varieties, high performance processes and flexible production systems result in an increased complexity in the product design, process development, factory and production planning and factory operation. To handle this complexity, new knowledge-based methods, technologies and tools to model, simulate, optimise and monitor planned and existing manufacturing systems are required.Apps4aME aims at the comprehensive consideration of ICT-based support of Manufacturing Engineering in all the above mentioned domains, called advanced Manufacturing Engineering (aME). The different life cycles will be aligned by the development of a reference model that provides a detailed overview of all relevant domain specific and inter-domain interdependencies. This life cycle-oriented model enables an integrated product design, process development, factory planning as well as production planning and factory operation. All stakeholders in these activities will be supported by Engineering Apps (eApps) that will be conceived, developed and validated with two industry-driven scenarios, implemented in three demonstrators: automotive, machining and food industry. These solution-oriented and service-based software components, systems or digital tools will enable a holistic planning and optimisation of products, processes and factories along their aligned life cycles without creating an overloaded, hardly manageable system. The realization of Apps4aME will increase the productivity in all Manufacturing Engineering activities with creating more reliable and efficient manuf
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Thematic Network for ETIS Development' to be submitted under Fifth Framework.

assistant: **Abstract**

The primary objective of ETIS-LINK is to provide centralised, clear co-ordination of ETIS development in order to help ensure the quality and usefulness of ETIS, smooth and swift consensus among the involved parties, and an effective up-take of the results by the Commission, Member States and other users. Sub-objectives are to: Integrate relevant 4th and 5th FP research outcomes (models and data) into ETIS; Provide strategic direction for and assessment of the ETIS interface and database; Co-ordinate ETIS development efforts, facilitate the dissemination of its results, and provide technical and administrative support; Bring together experts (within the disciplines of database and software development, transport policy, and sustainable mobility) and users (e.g., policy-makers, analysts, and authorities) for discussions to create consensus and generate support.