RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Image processing for enhanced cinematography'.

assistant: **Concept**

The objective is to develop image processing algorithms for cinema that allow people watching a movie on a screen to see the same details and colors as people at the shooting location can. It is due to camera and display limitations that the shooting location and the images on the screen are perceived very differently.We want to be able to use common cameras and displays (as opposed to highly expensive hardware systems) and work solely on processing the video so that our perception of the scene and of the images on the screen match, without having to add artifical lights when shooting or to manually correct the colors to adapt to a particular display device.Given that in terms of sensing capabilities cameras are in most regards better than human photoreceptors, the superiority of human vision over camera systems lies in the better processing which is carried out in the retina and visual cortex. Therefore, rather than working on the hardware, improving lenses and sensors, we will instead use, whenever possible, existing knowledge on visual neuroscience and models on visual perception to develop software methods mimicking neural processes in the human visual system, and apply these methods to images captured with a regular camera.From a technological standpoint, reaching our goal will be a remarkable achievement which will impact how movies are made (in less time, with less equipment, with smaller crews, with more artistic freedom) but also which movies are made (since good-visual-quality productions will become more affordable.) We also anticipate a considerable technological impact in the realm of consumer video.From a scientific standpoint, this will imply finding solutions for several challenging open problems in image processing and computer vision, but it also has a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Eco-design and Validation of In-Wheel Concept for Electric Vehicles'.

assistant: **Concept**

Promotion of Electric Vehicles is strategic for the European Community, but nowadays battery performance is still poor and all forecasts for near future transport electrification suggest that A-B class EV cars with limited range are the first step to develop. Even in the actual economic crisis, global demand of A-B class cars is expected to grow by about 5.3% in 2010, with a positive sale scenario in the next years. In-wheel electric motor architecture holds major advantages for these A-B class, allowing high modularisation of the vehicle architecture, increased interior space and improved driveability. However, current existing solutions for in-wheel motor are still in prototype phases, resulting in non-existence of A-B class EV car commercialized and equipped with in-wheel motor, even though the predicted market for this technology is 100K vehicles for 2015.The main objective of this proposal is the design, development and validation of a complete in wheel motor assembly prototype (electric motor, power electronics, reduction gear, structural parts and wheel), based on a McPherson corner suspension topology, to meet the defined car top level specifications. The main technical risks associated with the use of an in-wheel concept are the thermal stress under extreme operation conditions, vehicle dynamics, driveability, safety and durability. The proposed baseline concept will be based on an air cooled motor in wheel concept, with conventional airflow driven by vehicle, and forced airflow provided by an innovative wheel design. Detailed specifications of extreme operation conditions will be defined and validated by the OEM, during the project, including the hot day-cold day conditions, representative of vehicle extreme use. During the assembly and testing phase, the aspe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'High Performance and Embedded Architecture and Compilation' (HiPEAC).

assistant: **Innovation**

HiPEAC is a coordination and support action (CSA) that aims to structure and connect the European academic and industrial research and innovation communities in computing systems (i) by increasing the industrial membership, (ii) by integrating the European innovation community, (iii) by organising activities to connect the research and innovation communities, (iv) by stimulating collaborations, (v) by producing a vision document on the future of computing systems in Europe, and (vi) by professionally disseminating the research outcomes in and beyond the European computing systems community.The HiPEAC CSA is meant to be the continuation of four successful networks with the same name (HiPEAC1-4). HiPEAC will leverage the existing community, the expertise and the set of instruments that were developed since 2004 and work on the following objectives: structuring and connecting the European computing systems community, cross-sectorial industrial platform-building, constituency building and consultations, clustering of related research and innovation projects, and road-mapping for future research and innovation agendas.The overall approach of the HiPEAC CSA is that it wants to bring together all actors and stakeholders in the computing systems community in Europe – especially EU-funded projects, SMEs and the innovation community – in one well-managed structure where they can interact, disseminate/share information, transfer knowledge/technology, exchange human resources, think about future challenges, experiment with ideas to strengthen the community, etc.The HiPEAC CSA will support its members and projects with tasks that are too difficult/complex to carry out individually: vision building, professional communications, recruitment, event management at the European level. By
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'DEVELOPING PRINCIPLES of a EUROPEAN PUBLIC LAW' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

This programme aims also the creation of a new generation of law researchers with new capabilities in comparative analysis in European within a scientific system of European Public Law. The European Court of public law. As the research results will be published, the indirect Justice is developing principles of common European public law through a systematic comparative analysis of national legal orders deducted from training of other researchers will also be guaranteed. general principles, common to all legal orders of member states". This is also the work done by the European Group of Public Law since its foundation. A better capability of reception in all levels of exercise of public powers, within a common scope which can only be a better adaptation to common general principles is needed. First, we will deduct from the whole of European public law converging principles in the vaste area of substantial administrative law in the light of European law, constitutional law and human rights. Then, we will apply those results in one by one all the important areas of application of European public law in order to give the new perspective and dimension of the European Union law. "
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Mediterranean desertification and land use. Project 2: target areas' (1994-1998).

assistant: **Concept**

The objective of this Project is to apply and integrate the existing knowledge, obtained in the different MEDALUS projects in targeted areas along the Northern Mediterranean which are already desertified or threatened by desertification at regional scale.The work will concentrate on the following aspects: (a) Identification and mapping of environmentally sensitive areas (ESAs) to desertification. (b) Definition of ESAs to desertification based on sets of measured attributes such as climate variability, ecosystems, land use changes, land abandonment, and landscape characteristics. (c) Investigation of specific processes involved in land degradation and desertification. (d) Development and improvement of counter measurements and strategies for sustainable management of land resources and protection against desertification. The project involves the detailed study of the issue of desertification mitigation, policy making, and regional level interactions in four areas along the northern Mediterranean and the Atlantic coastline which in particular are located in Alentejo (Portugal), Guadalentin-Segura basins (Spain), Agri valley (Italy), and Lesvos (Greece). The studied sites are on a variety of landscapes and lithological units, and under a number of land-uses representative of the Mediterranean region, such as semi-natural forests and shrubland, abandoned agricultural land or agricultural land. The important results expected from this project are the following: (a) Presentation and documentation ESAs to desertification in the Mediterranean region. (b) Insights into the actions required to meet specific problems which, while arising and set in the context of the individual target areas, have wider regional significance. (d) Development of a methodology for mapping ESAs which
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Mechanical Characterisation of Nucleic Acids using Single Molecule Methods'.

assistant: **Concept**

Nucleic acid (NAs)-based therapies have started to yield major advances in the treatment of human disease. New approaches for understanding NA structure and function are required to extend the boundaries of todays gene editing technologies, cancer therapies, and mRNA vaccines. Single-molecule techniques have revolutionised our understanding of NAs and their interactions with therapeutic oligonucleotides, small molecules, and proteins. However, for Europe to remain competitive in this area, new expertise is urgently required in single-molecule NA analysis, which intersects the fields of physical chemistry, biophysics, NA synthesis, and computation. MeChaNiSM will train the next generation of European scientific leaders in the development and use of single-molecule biophysics techniques where they will investigate critical interrelated question regarding the structure, dynamics, function, and interactions of NAs. To do this, our Doctoral Candidates (DCs) will:- Unravel high-resolution NA structures and intramolecular forces with modified bases- Understand the conformation and dynamics of NAs at the single-molecule level- Develop next-generation therapeutics for treating genetic diseasesMeChaNiSM connects world-leading researchers working in the fields of single-molecule biophysics, NA chemistry, and computational modeling with outstanding industrial partners working in complementary fields. In addition to conducting world-class research, our DCs will understand industrial needs, have know-how in running multidisciplinary research, and will be immersed in a broad collaborative network connecting academia and industry. Our DCs will provide vital future breakthrough applications in NAs and single-molecule analysis to pharmaceutical and biotechnological industries where the d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Asset Bubbles and Economic Policy' (ABEP).

assistant: **Innovation**

Advanced capitalist economies experience large and persistent movements in asset prices that are difficult to justify with economic fundamentals. The internet bubble of the 1990s and the real state market bubble of the 2000s are two recent examples. The predominant view is that these bubbles are a market failure, and are caused by some form of individual irrationality on the part of market participants. This project is based instead on the view that market participants are individually rational, although this does not preclude sometimes collectively sub-optimal outcomes. Bubbles are thus not a source of market failure by themselves but instead arise as a result of a pre-existing market failure, namely, the existence of pockets of dynamically inefficient investments. Under some conditions, bubbles partly solve this problem, increasing market efficiency and welfare. It is also possible however that bubbles do not solve the underlying problem and, in addition, create negative side-effects. The main objective of this project is to develop this view of asset bubbles, and produce an empirically-relevant macroeconomic framework that allows us to address the following questions: (i) What is the relationship between bubbles and financial market frictions? Special emphasis is given to how the globalization of financial markets and the development of new financial products affect the size and effects of bubbles. (ii) What is the relationship between bubbles, economic growth and unemployment? The theory suggests the presence of virtuous and vicious cycles, as economic growth creates the conditions for bubbles to pop up, while bubbles create incentives for economic growth to happen. (iii) What is the optimal policy to manage bubbles? We need to develop the tools that allow policy ma
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Elucidating the Evolution of Endothermy through an Endolymphomics Approach' (ENDOMICS).

assistant: **Innovation**

Endothermy, the ability to maintain a stable internal body temperature, is a key evolutionary steppingstone that allows animals to thrive in diverse environments, sustain high activity levels, and achieve greater reproductive success despite increased energy demands. This thermoregulatory strategy has led to complex behaviors and evolutionary innovations, enabling endothermic animals, like birds and mammals, to dominate ecosystems throughout time. However, the origins of endothermy remain hotly debated. The ENDOMICS project aims to contribute to this debate by exploring the evolution of endothermy through advanced metabolomics and proteomics analyses of endolymph across various species. Endolymph, a fluid in the inner ear that monitors head movements and allows hearing, appears to vary in viscosity between taxa, detrimentally impacting ear biomechanics. By studying the proteins and metabolites in endolymph, we can understand the factors behind these variations. For instance, birds seem to have adapted to higher body temperatures by altering the chemical composition of endolymph, increasing its viscosity. We hypothesize this change to be linked to augmented presence of proteins/metabolites, known to increase biofluids’ viscosity, offering a cornerstone piece of information for understanding the onset and evolution of endothermy. ENDOMICS trailblazes the study of variation in the composition of endolymph across taxa. Our findings will clarify the fossil record, providing a deeper understanding of extinct species' biology by estimating their physicochemical properties from living counterparts. The study's results also have broad implications, including informing climate change adaptation, advancing treatments for hearing/balance disorders, and fostering innovation in synth
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Oncolytic viruses for the treatment of pediatric brain tumors: An integrated clinical and lab approach' (ViroPedTher) targeting Horizon 2020.

assistant: **Abstract**

The overreaching goal of my lab is to improve the prognosis of patients with high-risk pediatric brain tumors. To this end, I propose to integrate clinical and lab-based research to develop tumor-targeted oncolytic adenoviruses with the capacity to elicit a therapeutic immune response in those tumors. Our research will use novel and relevant models to accomplish the experimental aims. We have previously worked with Delta-24-RGD (DNX-2401) a replication-competent adenovirus that has been translated to the clinical scenario. In 2017, the first clinical trial phase I with DNX-2401 for newly diagnosed Diffuse Intrinsic Pontine Gliomas (DIPG; a lethal pediatric brain tumor) opened propelled by my team. Preliminary results from the first trials revealed that the intratumoral injection of the virus instigated an initial phase of oncolysis followed by a delayed inflammatory response that ultimately resulted in complete regression in a subset of the patients without associated toxicities. I hypothesized that enhancement of the immune component of the DNX-2401-based therapy will result in the complete regression of the vast majority of pediatric brain tumors. In our specific approach, we propose to understand the immune microenvironment of DIPGs and the response to viral therapy in the context of the trial. Moreover, that knowledge will leverage the design of Delta-24-based adenoviruses to recruit lymphocytes to the tumor with the competence of different type of ligands to activate the tumor infiltrating lymphocytes. I expect that this combinatorial innovative treatment will efficiently challenge the profound and inherent tumor immunosuppression and, in turn, will elicit a robust anti-tumor immune response resulting in the significant improvement of the prognosis and quality of l
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'INTERSECTIONS'.

assistant: **Concept**

This edition of European Researcher's Night, run independently of all other NIGHTs, will provide a platform from which researchers and publics across Europe can participate to create a truly pan-national series of events showcasing the international and intersectional nature of research as well as the relevance of, and contribution to research that the public can make.  INTERSECTIONS is developed from past success in international delivery of a group of seven NIGHTs across Europe. This experience has shown international delivery can be meaningful and rewarding, and demonstrated the barriers and drivers to a successful international and intersectional delivery. We propose now to expand on this and provide dedicated support for a pan-European delivery.  In 2021 INTERSECTIONS will run a modest group of activities that we are confident are able to run on an international basis with significant impact and meaningful outcomes for all stakeholders from researchers to audiences. This truly pan-European research showcase event, connecting researchers, audiences, and NIGHTs, will showcase research and its relevance to all European citizens.


**Keywords:** Science communication,  Public Engagement,  Intersectionality
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Hyperspectral Fiber Photometry for Flexible, Multiplexed Optical Measurements of Brain Function' (HyFiPhotometry) targeting Horizon Europe.

assistant: **Abstract**

Fiber photometry allows the activity of molecularly defined neuronal populations to be measured in freely behaving animals. The method is based on an implanted optical fiber through which fluorescent genetically encoded indicators of cellular activity, metabolites or signaling molecules can be monitored and is widely used in neuroscience research. However, conventional photometry systems are not flexible and typically limited to a fixed configuration of one or two readout channels. We will develop a new product based on a radically redesigned concept of fiber photometry called Fused Fiber Photometry (FFP). This new design is highly flexible and allows the fiber photometry setup to be easily reconfigured to a large number of spectral configurations at low cost. Furthermore, by combining spectral detection with spectral control of the fluorescence excitation signal, we will realize hyperspectral fiber photometry. Fused fiber photometry and hyperspectral photometry have the potential to gain large attraction in the academic research, industrial R&D and manufacturing processes, and in medical diagnosis. The technique has therefore high commercialization potential and a competitive advantage over existing commercial systems. It allows companies to offer a simple, out-of-the-box, turnkey system that can be easily modified and upgraded to meet user requirements. Our goal is to develop a commercializable hyperspectral fiber photometry system based on FFP. We will work hand in hand with established industrial partners to bring the system to market. By realizing HyFiPhotometry in this PoC project, want to exploit the full potential of hyperspectral photometry and demonstrate the feasibility of the basic idea. In the long term, we aim it to drive inventiveness in the fields of bio