RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The Dynamical and Structural Basis of Human Mind Complexity: Segregation and Integration of Information and Processing in the Brain' (DYSTRUCTURE), addressing dissemination and exploitation.

assistant: **Impact**

Perceptions, memories, emotions, and everything that makes us human, demand the flexible integration of information represented and computed in a distributed manner. The human brain is structured into a large number of areas in which information and computation are highly segregated. Normal brain functions require the integration of functionally specialized but widely distributed brain areas. Furthermore, human behavior entails a flexible task- dependent interplay between different subsets of these brain areas in order to integrate them according to the corresponding goal-directed requirements. We contend that the functional and encoding roles of diverse neuronal populations across areas are subject to intra- and inter-cortical dynamics. More concretely, we hypothesize that coherent oscillations within frequency-specific large-scale networks and coherent structuring of the underlying fluctuations are crucial mechanisms for the flexible integration of distributed processing and interaction of representations.The project aims to elucidate precisely the interplay and mutual entrainment between local brain area dynamics and global network dynamics and their breakdown in brain diseases. We wish to better understand how segregated distributed information and processing are integrated in a flexible and context-dependent way as required for goal-directed behavior. It will allow us to comprehend the mechanisms underlying brain functions by complementing structural and activation based analyses with dynamics. We expect to gain a full explanation of the mechanisms that mediate the interactions between global and local spatio-temporal patterns of activity revealed at many levels of observations (fMRI, EEG, MEG) in humans under task and resting conditions, complemented and further c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'A novel approach into modeling origin and development of ovarian cancer' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

High grade serous ovarian cancer (HGSOC) is the most common and lethal subtype of ovarian tumors, and is the 5th leading cause of cancer related deaths among women in the western world. Recent studies have pointed at the fimbriae of the fallopian tube (FT) as one of HGSOC’s main origins. The existence of FT stem cells (SCs) has been suggested, however, their isolation and characterization have been so far elusive. Given the potential of SCs to accumulate mutations, these cells may represent one of the cellular origins of HGSOC.This project is aimed at identifying SCs of the FT, evaluating their tumorigenic capacity and establishing a novel in-vitro human model for HGSOC development. Preliminary screening experiments of well-established SC markers have identified Lgr6 and Troy expression in the mouse oviduct. These putative SC populations will be further characterized and their capacity to maintain tissue homeostasis will be analyzed by lineage tracing experiments. Next, mouse and human organoid culture systems of FT and HGSOC will be generated. Mutating normal FT organoids in specific genes, using the CRISPR/Cas9 system, will enable following putative SCs tumorigenic capacity upon their injection to mice. Furthermore, it will generate an innovative in-vitro model of ovarian cancer development. Finally, HGSOC organoids will be used to model and follow chemotherapy resistance acquisition.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Framework of Integrated Technologies for User Centred Products' (FIT4U).

assistant: **Innovation**

Ongoing social and economic globalization processes will offer major challenges on the global market for consumer oriented manufacturing sectors. In particular, the shoes and gloves markets are expected to grow by more than 25% within the next 5 years, and the market niches for high value added shoes and gloves are expected to grow even faster. As a consequence there is today a unique opportunity for the European Footwear and Sport Industries to improve their competitiveness on such market segments. To face such a challenge the present project will develop a new engineering framework for both products & processes integrating: new technologies and devices to integrate the consumer in shoes and gloves conception, specification and design; innovative 3D knowledge based integrated design tools; micro and nano devices providing shoes and gloves with innovative sensing and actuating functionalities; innovative high-performing materials with self-adaptive capabilities; adaptive production processes and technologies; new bio-materials and clean production processes. The expected outcome of the proposed project will be an integrated technology framework for the engineering of fully personalised shoes and gloves based on a 3 to 5 days time-to-market criterion. Such a framework will be validated and assessed on pilot production lines, and new differentiated consumer-centred shoes and gloves will be delivered as fully engineered prototypes. Main objectives of present project proposal are to raise competitiveness of the European Footwear and Sport Industry on the shoes and gloves high value added global market niches, so giving the opportunity to many European companies along the considered value chains to grow by more than 25% in the next 5 years; and to improve consumers satisfact
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'A Neuroscientific Foundation of Program Comprehension' (2021-2027), addressing dissemination and exploitation.

assistant: **Impact**

The pivotal role of software in our modern world mandates strong requirements on quality, correctness, and reliability of software systems. In software development and maintenance, the ability to understand program artifacts plays a key role for programmers to fulfill these requirements. Despite significant progress, research on program comprehension has a fundamental limitation: program comprehension is a cognitive process that cannot be directly observed, which leaves considerable room for misinterpretation, uncertainty, and confounders.    In Brains On Code, we will develop a neuroscientific foundation of program comprehension. Instead of merely observing whether there is a difference regarding program comprehension (e.g., between two programming methods), we aim at precisely and reliably determining the key factors that cause the difference. This is especially challenging as humans are the subjects of study, and inter-personal variance and other confounding factors obfuscate the results. The key idea of Brains On Code is to leverage established methods from cognitive neuroscience to obtain insights into the underlying processes and influential factors of program comprehension. Brains On Code will pursue a multimodal approach that integrates different neuro-physiological measures as well as a cognitive computational modeling approach to establish the theoretical foundation. This way, Brains On Code will lay the foundations of measuring and modeling program comprehension and offer substantial feedback for programming methodology, language design, and education. Addressing longstanding foundational questions such as ""How can we reliably measure program comprehension?"", ""What makes a program hard to understand?"", and ""What skills should programmers have?"" will bec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Tangible Acoustic Interfaces for Computer-Human Interaction'.

assistant: **Concept**

A common problem with existing input tangible interfaces (keypads, mice and touch screens) is their inflexibility in restricting the mobility of users, constraining them to be in certain locations during interaction with the computer. Lack of robustness is another disadvantage, limiting the areas of application. This project explores how physical objects, augmented surfaces and space can be transformed into tangible-acoustic embodiments of natural seamless unrestricted interfaces. The ultimate goal is to design tangible interfaces that employ physical objects and space as media to bridge the gap between the virtual and physical worlds and to make information accessible through touchable objects as well as ambient media.The method to be developed is based on the principle that interacting with a physical object modifies its acoustic pattern. By visualising and characterising such acoustic patterns, it will be possible to transform almost any object into an interactive interface, opening up new modes of computer-user interaction for responsive environments. Because of their numerous advantages over other methods, including the spatial freedom they provide to the user, the robustness with which they can be constructed and the ease of accommodating multiple users simultaneously, acoustic-based interfaces will become a major sensing paradigm in the future, implying enormous potential for the whole computer and information industry. New applications will include wall-size touch panels, three-dimensional interfaces, immersive VR sensors, and robust interactive screens for harsh industrial environments.The Tai-Chi project will target the following specific technology areas: research into acoustic transmission behaviours in various media, development of novel acoustic sensors fo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Theory of Two-Dimensional Materials: Graphene and Beyond' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

This projects aims to explore physics of the new class of materials: atomically thin films of layered crystals. Graphene, because of its extraordinary electronic properties, will be a major focus of this project. In view of application of graphene in electronics, we shall model electronic transport and dynamical properties of devices based upon epitaxial graphene (monolayer and bilayer), graphene deposited on atomically flat substrates, and chemically modified graphene. In the family of graphene, the bilayer allotrope is the less understood, though it has already been discovered to have quite unique electronic properties, and we shall develop theories of the electron-electron correlation effects, quantum transport and quantum Hall effect in bilayer graphene. But beyond graphene, we shall also investigate electronic properties of ultrathin films of hexagonal boron nitride on account of its insulating and optical properties, and on account of their use in hybrid devices such as graphene/h-BN based transistors. In parallel, we shall search for new opportunities in the world of two-dimensional materials beyond graphene. For this, we shall model theoretically electronic properties, correlations effects, optical properties, and electronic transport properties of single layers and bilayers of hexagonal transition-metal dichalcogenides with a broad range of composition and ultrathin films of bismuth-based trichalcogenides.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Borate Free Cleaners for Aluminum Alloys'.

assistant: **Innovation**

The project propose to analyze four new borate-free agents (cleaners), able to remove any grease or solid soils or contaminants adsorbed or chemically bonded to the surface of the parts from previous operations. Different borate-free formulations will be tested and investigated in a pilot line evaluating the cleaning efficiency compared to formulations containing borates and also evaluating the impact in term of corrosion or damage of these new formulations on two of the most critical aluminium alloys utilized in aeronautics. Together with the identification of the optimal cleaner and its processing window the project will provide indications on the analytics to be performed on the bath and the limiting values for selecting bath maintenance or replacement of the full solution. Finally, an evaluation on small and medium size parts of the whole anodizing sequence will be performed with particular reference the major requirements of the processes, like adhesion, corrosion properties and fatigue life.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Study of thin dielectrics films by scanning thermal microscopy and complementary techniques' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

Research objectives and content The question of power dissipation is a challenging issue for ULSI microelectronics power devices. The purpose of the project is to study thermal properties of very thin dielectrics films by a new and promising nanotechnique: scanning thermal microscopy. The study will involve the development of the thermal microscope, focusing on the reliability of measurements and the microscope capability to yield quantitative information on thin layers thermal properties. After testing the microscope on simple and well-known samples, thin layer of dielectrics, chosen for their potential applications in power devices, will be studied. These samples will also be characterised with different techniques: other scanning probe microscopy, nuclear and optical techniques, to obtain a complete knowledge of their physical and chemical properties. Training content (objective, benefit amd expected impact) The project requires experimental skills and leads to the development of a new characterization method of very thin films implying a clear comprehension of the involved physical phenomena. This will greatly extend my competence to the field of nanotechnology as well as deepen my knowledge of thin films. Links with industiy / industrial relevance (22) The project is conducted in close collaboration with the SGS-Thomson site of Agrate Bianza (MI) where the MDM laboratory is located. This special situation favores technological transfert from university research laboratory to microelectronics industry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Nonlinear dynamics of the solar-terrestrial environment' (PLASMADYNAMICS), addressing dissemination and exploitation.

assistant: **Impact**

The objective of this project is to perform modeling and observation of the nonlinear dynamics of the solar-terresrial environment using the innovative complex systems approach to investigate ""How short-term solar variability affects the geospace environment"". This is the challenge of Task Group 3 of CAWSES-II (Climate and Weather of the Sun-Earth System), an international program from 2009 to 2013 sponsored by ICSU (International Council of Scientific Unions) established to significantly enhance our understanding of the space environment and its impacts on life and society. This project will execute two tasks. First, it will build a nonlinear dynamical model of Alfven waves and intermittent turbulence in space plasmas, in the absence and in the presence of noise, based on numerical simulations. Second, it will carry out nonlinear analysis of coherent structures and intermittent turbulence in solar and interplanetary plasmas, based on in-situ and remote observational data and images. Large-amplitude interplanetary Alfven waves are solar wind drivers of geomagnetic activities such as High-Intensity Long-Duration Continuous Auroral Activities (HILDCAAs) events. Coherent structures such as Coronal Mass Ejections (CMEs) and current sheets are manifestations of intermittent turbulence processes operating in the space environment.  This project will make relevant and far-reaching contributions to advance our knowledge of the complex spatiotemporal dynamics of space plasmas, and their applications in solar-terrestrial relation, space weather, and other frontier problems in space physics.  It will enhance the activities of Space Weather developed in LESIA and Paris Observatory, and the ESA SSA (Space Situational Awareness) program which will enable Europe to autonomously dete
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Remote Sanitation – New sustainable sanitation solution for remote areas' in the context of a Horizon 2020 call.

assistant: **Objectives**

Low quality sanitation is a huge global, growing environmental and health problem with large costs to society. Poor hygieneand waste treatment results in lower productivity, spreading of diseases and pollution. There is a lack of efficient and greensolutions addressing specific sanitation needs in remote areas such as: refugee and military camps, remote industrial andhousehold sites.The awareness of the problem is increasing and authorities have begun to act within this area - e.g. the United NationsEnvironment Programme has stated that “every dollar invested in safe water and sanitation has a pay back of US$3 to US$34 depending on the region and the technology deployed”.Aalborg Rørteknik ApS (ART) have invented a new sanitation solution, applicable in remote areas without access to sewageinfrastructure. This turnkey system solution, consisting of 3 main modules (hygiene unit, waste water treatment, sludgehandling), has superior advantages to alternative solutions by being e.g. mobile, reusable, hygienic, environmentally friendlyand affordable. In addition, ART will include services such as camp architecture, installation and maintenance, ensuringmaxmized efficiency of the solution.Red Cross have been an important contributor in the project and also led the way to market introduction targetting aidworkerbase camps. The unique selling points of the new solution are estimated to secure a market share of 15% within 5years, resulting in an enhanced profitability and significant growth for ART.In this phase 1 study, ART will perform a demonstration exercice, as well as conduct extended market studies to develop anappropriate IP strategy, in preparation of a phase 2 project. The outcome of this stage, will be a feasibility report andbusiness plan. This project and requested f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'TOPIC: Targeting Cytotoxic Protein Oligomers' to be submitted under Seventh Framework.

assistant: **Abstract**

Parkinson's disease and Huntington's disease are highly debilitating diseases for which no disease modifying treatment is available. This EID proposal, called TOPIC (Targeting Cytotoxic Protein Oligomers), will train 2 ESRs to target the oligomeric protein aggregate which accumulates in these diseases. These oligomers occur under conditions which eventually lead to the accumulation of fibrillar amyloid deposits. However, there is increasing consensus that the amyloid state is biologically inert and the cytotoxic species is the oligomeric structure. Our approach rests on the working hypothesis that the cytotoxic oligomers engage in a number of unwanted interactions with proteins and membranes. The 2 ESRs will combine proprietary technology to stabilize these oligomers with state-of-the-art mass spectrometry and biophysical techniques to identify, quantitate and rank these interactions within the context of the cellular interactome. The next goal (building directly on the EID outcome but outside its present scope) is to develop small-molecule inhibitors of these interactions as a therapeutic strategy to eliminate cell death and disease progression. This training programme offers a unique opportunity for the 2 ESRs to carry out central parts of translational research in both an academic and SME setting, spanning a multitude of different cellular, biophysical and mass spectrometric techniques of general use in the life sciences.Our target oligomeric proteins are α-synuclein (Parkinson’s Disease) and the N-terminal part of exon 1 of huntingtin (Huntington’s Disease). By analysing two different proteins in parallel projects, we will be able to validate the robustness of our approach and potentially identify generic small molecules to target misfolded protein oligomers in gene