RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Missionary Engagements, Extractive Histories, and Indigenous Land' under Horizon Europe.

assistant: **Concept**

This research project aims to study the entanglements and discrepancies between indigenous understandings of history and colonial narratives created by missionary intervention amongst the Shuar people of lowland Ecuador. It will examine how history, indigenous memory, and cultural transmission have been developed and produced in the context of missionisation and colonial pressure. It aims to understand how colonial history still impacts indigenous politics today, shaping current indigenous engagements with large-scale resource extraction and allowing extractive capital to endure and perpetuate over time. To achieve these objectives, this research reviews the historical archives available in the region from the Salesian and Franciscan missions since the late 19th century, will collect and archive film footage of testimonial memories from indigenous participants on their complex relationship with the missionary endeavours and boarding schools, and will map how missionary presence shaped indigenous land. The use of these three different methodologies will be combined to provide a clear ethnographic study that aims to understand and describe the long-term effects of colonial entanglements on people’s attitudes, thinking, and current political developments. Overall, this research project is concerned with colonial residues and proposes to look at land demarcation, history, and cultural transmission to understand not only the impacts of colonialism in its tangible political ubiquity but also in its pervasive and intangible influence over concepts that help people define their worldview.


**Keywords:** Colonization, Social Change, Boarding Schools, History, Indigenous Memory, Missionary Archives
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Material counting technologies in numerical cognition' under Horizon 2020.

assistant: **Concept**

Material counting technologies (MaCoTech) play a critical role in developing human numerical concepts like numbers, numerical relations, and arithmetical operations. Yet today, our understanding of how these concepts emerge is still very restricted, as the influential effects of prehistoric MaCoTech and Ancient Near Eastern (ANE) mathematics are difficult to assess and have been mostly neglected in modern-day research.The comparison of ANE MaCoTech to its extant counterparts of Oceania will allow investigating the impact of multiple MaCoTech on numerical elaboration, and to gain a deeper understanding of the evolution of numerical concepts in socio-historical contexts. This will include the first-ever generation of a dataset of ANE and Oceanian MaCoTech and the development of innovative strategies for cross-cultural data analysis. The project will apply state-of-the-art paradigms on the nature of human cognition to improve our understanding of how MaCoTech structure numerical concepts, which will generate novel insights into numerical origins and the role of materiality in human cognition. It will also engender new understandings of psychological–behavioral–material interactions with potential utility in cognitive-psychological research.As a cognitive archaeologist with a strong background in the materiality of numbers, I want to be among the first to work at a novel interdisciplinary crossway connecting the fields of archaeology, psychology, anthropology, linguistics, and Assyriology. With a renowned researcher in numerical cognition as my supervisor and my own expertise in ANE number systems, ANE archaeology, and philosophy of mind, this will bring me in the optimal position to foster an international high-level career in numerical cognition research at the interface
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Multi-strain indigenous Yeast and Bacterial starters for ‘Wild-ferment’ Wine production' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Traditionally, wines were produced by the resident grape/winery microbiota, whereas nowadays commercial Saccharomyces cerevisiae and Oenococcus oeni starter cultures are widely used to ensure a manageable process. Despite advantages, this may lead to sensory resemblance of wines from diverse origins. Currently, the competitive nature of global wine market urges for the production of premium wines with regional character. Consumers also call for allergen-free wines made according to natural and organic procedures. To this end, the use of indigenous S. cerevisiae or non-Saccharomyces (wild) yeasts and lactic acid bacteria (LAB) is a tool to create wine complexity and authenticity, while selected LAB may effectively control malolactic fermentation and thereby eliminate biogenic amines (BA). The innovative scope of this project is to combine native S. cerevisiae with wild yeasts and native O. oeni with other LAB in the development of peculiar multi-species yeast and bacterial starter blends, respectively. These formulations will be carefully designed to fulfill all the essential and desirable winemaking properties to serve as starters in induced wild fermentations for the production of specialty organic or conventional wines. For this purpose, the biodiversity of key EU viticultural areas will be thoroughly screened to identify strains of enological importance as per their phenotypic characters and genetic traits. Their eligibility will be validated in plant-scale fermentations and wines will be evaluated by sensory analysis and consumer acceptance testing. Outcomes will enable (a) launching of ‘wild ferment’ technology in winemaking, (b) production of innovative, safe terroir wines and (c) compliance with rules on organic wine production and BA content. By these means, the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Evolution of gene mobility: how mobile elements shape the function and sociality of microbial communities' (EVOMOBILOME).

assistant: **Innovation**

Prokaryotes evolve rapidly new functionalities by horizontal gene transfer delivered by mobile genetic elements (MGE). MGE increase relatedness between individuals and thereby might also promote the establishment of microbial social networks. Many studies have detailed the dynamics of specific systems in specific MGE. Yet, how MGE key and accessory functions evolve as a whole at the face of social dilemmas arising in microbial communities is largely ignored. Here, I aim at an integrative identification and analysis of self-mobilizable elements to unravel an evolutionary framework of MGE contributions to prokaryotic evolution.We will use sequence similarity, phylogeny and population genetics techniques to detail how elements propagate and are maintained in populations. We will investigate how accessory functions work together in relation to interactions between MGE and of MGE with the host. We will then quantify the long-term impact of MGE to the gene repertoires of prokaryotes by analysis of the patterns of their degradation and/or domestication using regulatory networks and population genetics. The analysis of secretion systems and effectors in mobile elements will enlighten the role of gene mobility in promoting social behaviours thorugh production of public goods. The previous results will then be used to query metagenomics datasets about the roles of gene mobility and secretion in the social evolution of natural microbial populations.This work will pioneer the application of theoretical works in population genetics and social evolution to the study of natural microbial communities by way of evolutionary genomics. Its integrative outlook will also provide essential breakthroughs in the understanding of the evolutionary history of mechanisms of gene mobility, e.g. con
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Categorical Interoception Project: How generalization and classification strategies link anxiety and interoception'.

assistant: **Innovation**

Bias in the perception of bodily sensations (interoception) can be dangerous or even fatal; for example, if we do not recognize signs of a stroke or take medication anytime we feel the slightest change in our body. Research consistently reports that anxiety is closely related to interoception and (mis)interpretation of bodily sensations, but little is known about more fundamental processes underlying this relationship. The aim of this project is to test whether categorization as basic perceptual process links anxiety and interoception via generalization and perceptual decision strategies. Bundling the continuous flow of interoceptive information into distinct categories such as “pain” or “pleasure” can facilitate perception and coping. By assigning sensations to interoceptive categories (e.g., symptom groups) we can infer information about causes and consequences and apply coping schemata fast and efficiently. Research on visual perception, however, suggests that anxiety can be related to excessive generalization which may turn into harmful over-generalization, particularly if stimuli are misclassified. We will test whether also in interoception, anxiety is related to excessive category-related generalization. Furthermore, we will test whether individuals higher in anxiety are more prone to take a “better safe than sorry” strategy and misclassify benign sensations (e.g., heartbeat and breathlessness associated with exercise) more often as sign of disease.We will test our hypotheses of categorization linking anxiety and interoception in a newly developed research paradigm. In contrast to traditional paradigms, it allows distinguishing interoceptive accuracy and bias. The project is of theoretical relevance by targeting fundamental processes linking anxiety and interocept
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Supporting Innovation in Healthcare Public Procurement-INNOHSUPPORT' to be submitted under Horizon Europe.

assistant: **Abstract**

InnoHSupport´s main goal is to bridge those gaps that hamper the progress in the definition, implementation, and adoption of innovative solutions in the healthcare ecosystem by offering a portfolio of advisory services for procurers, state-owned enterprises, SMEs and start-ups, research and technological organisations, innovation agencies and other organisations, like investors, responsible for promoting innovation procurement.These advisory services will include, among others, the provision of training materials, executive training interventions, methodologies for innovation procurement, dedicated coaching sessions, innovation showcases, scanning of relevant bidding opportunities, matching with potential bidding partners, acceleration services, etc.Project methodology is based on three pillars:-Pillar I. Capacity building focused on building capacities and skills in the innovation procurement ecosytem.-Pillar II. Inventory of innovation procurement advisory services oriented towards the design and testing of a comprehensive set of advisory services covering the whole innovation process cycle.-Pillar III. Collaboration and Matchmaking to foster the innovation ecosystem building by developing spaces for co-design and matchmaking.InnoHSupport is made by and for innovation actors:-the consortium brings together seven partners + two affiliated entities + one associated partner from six EU countries (ES, NL, IE, BU, BE, UK) including a consultancy firm, a university, a public buyer and several associations with highl expertise within the public procurement of innovation in healthcare systems;-our target groups involve the whole innovation ecosystem actors: public and private procurers, state-owned enterprises, SMEs and start-ups, research and technological organisations, inn
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Terahertz room-temperature integrated parametric source' under Seventh Framework.

assistant: **Concept**

This project will demonstrate an integrated terahertz (THz) emitter at room temperature, based on a parametric optical process in an AlGaAs device, combining strong material nonlinearity and high optical confinement. The approach followed is based on a quasi-phasematching scheme in the whispering-gallery cavity of a microcylinder containing self-assembled quantum-dots. Compared to existing THz sources like photoconductive antennas, photo-mixers, quantum cascade lasers and optical parametric generators, the TREASURE source will bring together several crucial advantages: room-temperature operation, electrical pumping, compactness, THz power above ~0.3 µW from a single emitter (1 µW in an array) , custom emission wavelength, spectral purity, an the perspectives of coherent detection and two-dimensional array schemes. This will be accomplished with the complementary competences of four world-class research groups, plus an industrial partner, leader in the THz technology.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'High Resolution Copernicus-Based Information Services at Sea for Ports and Aquaculture' (HiSea), addressing dissemination and exploitation.

assistant: **Impact**

The Sentinel missions and Copernicus Services provide a global view of environmental parameters of prime importance for climate and environmental research. The accuracy and high spatial resolution of the data play a crucial role in representing physical, chemical and biological processes. Models can develop precise parametrisations of these processes and of their complex interactions. HiSea, combing measurements and models, has an enormous potential to improve the understanding of the coastal environment. HiSea services will deliver information, readily available and with high resolution to fit seamlessly user‘s operation and management requirements. HiSea will provide a co-designed service that offers high resolution water quality data at sea answering to specific questions from the targeted port and the aquaculture sectors. HiSea will develop, in operational mode, novel Copernicus-based downstream services that will incorporate Copernicus Marine, Land and Climate Services Products, local monitoring data, and advanced modelling in the service integrated representing an added value for the potential Copernicus data users. The downstream service includes among others early warning alerts, alarms to potential risks for the daily activities; real time crisis management to simulate mitigation actions to adverse effects; automatic reporting on the key performance indicators; standard datasets; and building knowledge data base of cause-effect relations (business intelligence). From the data storage to the processing using Docker containers, the HiSea platform will be fully compliant to cloud deployment, prepared to DIAS infrastructure. The immediate market uptake of the HiSea services by the targeted ports and aquaculture users is guaranteed. Linking to the market and experie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'A multi-parametric Regulatory T cell Atlas in cancer to predict immunotherapy response, adverse autoimmune events and to identify novel therapeutic targets' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The advent of immune checkpoint inhibitors (ICI), that target regulatory pathways in T cells to unleash antitumor immune responses, has revolutionized cancer immunotherapy. However, despite the enormous success of ICI in the treatment of cancer, a significant proportion of patients do not respond, while responses are frequently accompanied by life-threatening autoimmune related adverse events (irAEs). Predictive biomarkers of clinical responses and new therapeutic strategies to harness anti-tumor immunity, while keeping autoimmunity in check represent a currently unmet need. Tregs, are an ideal candidate, since they are physiologically engaged in maintenance of self-tolerance, are the dominant suppressive population in the tumor microenvironment (TME), promote tumor growth, correlate with poor prognosis and importantly, represent a fundamental impediment of cancer immunotherapy success. Building upon my extensive expertise on Tregs in autoimmunity and cancer, the abundance of circulating Tregs in cancer patients, and preliminary data demonstrating a robust transcriptomic and metabolic reprogramming of circulating Tregs in advanced melanoma patients experiencing irAEs, RegSign proposes: 1) to integrate single cell mass-cytometric, transcriptomic, metabolic and stability analysis of circulating Tregs to create a “liquid biopsy” for prediction of ICI efficacy and irAEs development, 2) to identify novel Treg-based therapeutic targets via innovative humanized patient derived xenograft models and 3) to modulate Treg metabolic checkpoints for the management of irAEs. Decoding Tregs signatures in cancer will empower the discovery of personalized predictive biomarkers and novel targets for cancer immunotherapy.


**Keywords:** Biomarkers, cancer immunotherapy, therapeutic target
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'EU-China co-operation for strategic planning of Beijing digital Olympics programme' (ECOSPLAN), addressing dissemination and exploitation.

assistant: **Impact**

The strategic objectives of ECOSPLAN are to carry out joint EU-China strategic planning of the Beijing Digital Olympics Programme (DOP) towards a successful organisation of the 2008 Beijing Olympic Games and a long-term and strong EU-China industry co-operation in the IST field.The main activities of ECOSPLAN include:- Establishing the EU-China Olympic Cities Forum to strengthen exchange of experience and know-how related to development of the DOP;- Developing the strategic plan framework for the DOP and specifying the strategies and visions for the various sub-plans;- Defining a long-term strategy for speeding up the building of Digital Beijing;- Defining the technological platform for the DOP with a number of integrated and complementary information systems and services that comply with good international practices and embody Chinese characteristics;- Disseminating and exploiting ECOSPLAN results.Through the planned activities ECOSPLAN is clearly complementary to the initiative of the ongoing EU-China Working Group on Digital Olympics aiming to foster EU-China co-operation in the DOP. and it is expected to make significant contributions to the general and strategic objectives of the IST Priority, and particularly to the objectives of the Action Line 2.3.6 General Accompanying Actions. In fact, the joint EU-China strategic planning of the DOP is an effective approach to ensure a strong participation of European industry in this important international business case and to support a rapid adoption and transfer of a number of European IST technologies for applications in China for strong mutual interest and benefit. ECOSPLAN will thus provide a sound basis for a long-term and strong co-operation between the European and Chinese IST communities. It will in turn greatly in