RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Stimulating Performance of Ecosystems in Creative Territories and Regional Actors' (SPECTRA).

assistant: **Innovation**

The SPECTRA proposal embodies the collaborative vision of 8 partners (including 3 associate partners) representing 4 regional ecosystems – an emerging innovator region in Bulgaria (North-Central-BG), moderate innovator region in Ireland (Northern and Western), together with lead innovator regions in Denmark (Hovedstaden) and Germany (Berlin). SPECTRA will put in place key ingredients required to equip the emerging innovator and moderate innovator regions with a more responsive, resilient ecosystem, capable of growing and developing coordinated responses to many challenges creative industries are facing to achieve the National and European goals. This will be based on interaction with 2 successful initiatives - Media Deals Investment Network and Creative Business Network. SPECTRA will harness and multiply the power of individual ecosystem initiatives to enhance participation of financiers/investors and women innovators - resulting in enhanced, more inter-connected, diverse, gender-responsive, competitive, and sustainable ecosystems. Additionally, SPECTRA will include activities that will encourage development of joint strategies and amplify collaboration. Stakeholders will benefit extensively from the advanced business support models developed to fast-track start-ups, produce scale-ups, avail of best practice, new systems, structures and tools, as well as data-driven & carbon-reducing challenge-based innovation methods, case studies, role models, cross-sectoral and intra-territorial learning - engaging over 1000 stakeholders over 30 workshops, experiments/challenges, huddles and roundtables, supporting over 100 start-ups and SMEs and creating an excess of 300 new linkages. SPECTRA measures will be integrated within the context of policy, economic, societal framework and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'ERA-Net on INtesTInal MICrobiomics, diet and health, implementing JPI HDHL objectives' under Horizon 2020.

assistant: **Concept**

HDHL-INTIMIC (INtesTInal MICrobiomics) is a proposal for an ERA-NET Cofund in the field of food, nutrition and health to support the Joint Programming Initiative ""A Healthy Diet for a Healthy Life"" (JPI HDHL).There is a high burden of non-communicable diseases due to unhealthy diet and lifestyle patterns.  The intestine and in particular the intestinal microbiota have an influence on metabolic processes, thereby contributing to the development of lifestyle-related diseases.  The 26 members of the JPI HDHL are working together to develop means to (1) motivate people to adopt healthier lifestyles including dietary choices and physical activity, (2) develop and produce healthy, high-quality, safe and sustainable foods and (3) prevent diet-related diseases. Since 2012, JPI HDHL has implemented seven Joint Funding Actions (JFAs) with around 45 M€ national funding. In addition, the first ERA-NET Cofund under the umbrella of JPI HDHL, ERA-HDHL, has recently started, implementing an EC cofunded call on Biomarkers on Nutrition and Health with a committed budget of around 12 M€.Building on these achievements, HDHL-INTIMIC will now further enhance the collaboration between JPI member countries and between the JPI and the EC by providing a platform for implementing further JFAs  that address the needs identified in the JPI HDHL Strategic Research Agenda. In particular, a transnational Knowledge Platform on the interrelation of diet, intestinal microbiomics and health will be implemented via an EC cofunded call and an additional JFA. For this, the JPI HDHL members countries have increased their financial commitments comparing to a previous JFA on a similar topic, including also new partners in these activities. Moreover, HDHL-INTIMIC will launch 1-2 other additional JFAs in line t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Marker/reporter genes in microbial ecology', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Genetically modified microorganisms (GMMs) are being designed for use in the environment. The deliberate release of GMMs (eg biofertilisers and bio-pesticide) is regulated to ensure that the risk of hazardous consequences is kept to a minimum. Specific genes can be used as markers for monitoring of bacterial survival or as reporters for montitoring gene expression (activity). There are a variety of specific marker and reporter genes being developed; each with particular advantages and disadvantages. Marker techniques provide significant advantages for risk assessment studies in comparison with traditional methodologies and, when used in combination with other approaches, provide information which is essential for risk assessment of GMMs. This information arises directly from tracking of GMMS in dedicated risk assessment studies but also through more fundamental studies designed to increase our understanding of microbial ecology. It is necessary to have closer harmony of European Community efforts with national efforts regarding the rational basis of regulation of GMMs intended for release into nature; especially since marker genes and monitoring methods vary widely between different countries and even between different laboratories within the same country. Proper risk assessment of GMMs is dependent on the methodologies available for monitoring of released strains. A concerted evaluation of current and upcoming detection systems will provide the basis for development of standardised tests for assessment of the risk to humans and to the environment upon release. The goal of this concerted action is to enable key players within the European Union to interact within a common framework of proposal actions, for symposia and workshops concerning the use of marker genes and re
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Touch and design' under Sixth Framework.

assistant: **Concept**

The project aims at developing a novel system for shape generation and modification based on novel haptic interaction and intelligent shape manipulation operators in order to exploit existing manual skill of designers. Haptic technology will be integrated together with modeling operators for providing a working environment offering high degree of usability and acceptance, comfort of usage, flexibility for any kind of user, including inexperienced users. The system will capture the design intent, inferring commands to apply from designers haptic gestures. Designers will be able to manipulate generative constraints using their hands, and not mathematical equations and formula.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Point-of-care blood device for fast and reliable prediction of drug response in non- small-cell lung carcinoma patients from blood samples'.

assistant: **Concept**

Chemotherapy is the standard care for the treatment of non-small cell lung carcinoma (NSCLC) patients, however most of non-small cell lung cancer tumours are not sensitive to this treatment. As an alternative to chemoterapy, target therapy with gefitinib (epidermal growth factor receptor-tyrosine kinase inhibitor) has been used in clinical practice in patients with tumours harbouring mutations in EGFR gene, improving their treatment effectiveness. For that reason EGFR mutations analysis should be perform to support the treatment decision for a patient with NSCLC. Despite all the foreseen benefits of EGFR genotyping, the current PCR-based methods used have been shown some associated bottlenecks: i) use of complex samples (tumour biopsy embedded in Formalin Fixed Paraffin, FFPE), ii) require a better understanding from the clinical geneticist to accurately interpret the information provided and to setup the best line of therapy and treatment and iii) the assays are quite expensive and time-consuming. New age diagnostic tools, such as microfluidic platforms and nanodiagnostics are emerging technologies for DNA analysis requiring lower sample volumes and providing comparable sensitivity and specificity at lower costs. Nonetheless, sample preparation and detection of the result of a chemical analysis on-chip are still weak points in many lab-on-a-chip devices. The current proposal, aiming the integration of “all laboratory-based process steps” in one single step, is both challenging and feasible: development of a microfluidic chip that combines blood sample processing (DNA extraction/purification, multiplex amplification) and detection of EGFR mutations in tumour DNA by means of gold and silver-nanoparticles (Ag and Au-nanoprobes). Furthermore a microfluidic chip analyser wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Evaluation of the Efficiency of Artificial Reefs by Advanced Numerical Simulations - Towards Environmentally Friendly Coastal Protection' (EVERANS).

assistant: **Innovation**

The strategic objective of the project is to develop tools and methods to facilitate appropriate design of artificial reefs / reef breakwaters, applied in conjunction with or without beach nourishment, towards an environmentally friendly coastal protection. The specific targeted research objectives include: -  Verification and improvement of a RANSE/VOF CFD wave model (developed within the Marie Curie Fellowship) with available data from physical model test  -  Development of an ‘Extreme Wave Numerical Flume’ for evaluation the impact of extreme waves in coastal waters (numerical study on interaction of reef structures with tsunamis and coastal ‘freak’ waves) -  2D/3D Numerical study on ‘wave-pumping effects’, wave-driven currents, local scour and sediment transport around an artificial reef (using Hydrodynamics and Boussinesq Wave models, as well as a Sand transport model) -  Application to practical design of reef breakwaters with respect to protection of coasts against erosion and impact of extreme waves. Work will include: collect/process/analyse data; write software codes (numerical models); perform numerical simulations, write technical reports. Expected results are: -  An improved RANSE/VOF CFD model of wave environment (including simulations of solitary waves; regular (monochromatic) waves; irregular waves / group waves / freak waves; breaking waves) -   New knowledge on the mechanism of breaking of waves passing artificial reefs -  New knowledge on the mechanism of ‘wave-pumping effect’ and wave-driven currents in the vicinity of artificial reefs - New knowledge on the propagation and impact of extreme waves on coastal beaches and protection facilities -   Recommendations on practical design of reef breakwaters: optimizing geometry & other reef parameters; prev
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Sustainable Urban Consolidation CentrES for conStruction'.

assistant: **Objectives**

Currently freight transport represents 40% of the total transport emission and 32% in urban area. Many initiatives are under development to reduce costs and negative impact of freight and service trip in urban area. Some of them concern supply chain improvements and more specifically consolidation centre projects. Few study cases are dedicated to construction industry.However, urban population tends to grow, increasing the need to develop and reconstruct urban centres. Construction material logistic impact in urban area will intensify in terms of costs and negative impacts in urban area. Yet, only few experiences of Construction Consolidation Centres can be found.Among these initiatives, four are construction site specific (Stockholm, Utrecht, Berlin, London Heathrow) and only one is dedicated to several construction projects (London CC). Theses pilots studies have demonstrated reduced transportation impacts, positive effects on transportation efficiency and construction site productivity.Several limitations to the transferability of this concept are identified: one on hand the demonstrators were implemented in specific contexts (regulatory incentives, cities investment contribution, and specifics transport and logistics infrastructure issues) which are not the same in France, Spain, Italy and Luxembourg. On the other hand, economic viability has not been demonstrated.The project addresses the different requirements for transferability of supply chain optimization concepts as well as CCCs and new ways of working between supply chain stakeholders. The approach is to identify an integrated collaborative approach and business model among construction supply chain actors. Three main steps will be performed: analyse the current issues along the construction supply chain, pro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Aligning Research & Innovation for Connected and Automated Driving in Europe' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The mission of ARCADE is to coordinate consensus-building across stakeholders for sound and harmonised deployment of Connected, Cooperative and Automated Driving (CAD) in Europe and beyond. ARCADE supports the commitment of the European Commission, the European Member States and the industry to develop a common approach to development, testing, validation and deployment of CAD in Europe and beyond.ARCADE involves 23 partners, 43 associated partners and over 500 subscribers, jointly forming the CAD network of European experts and stakeholders from the public, industry and research sectors, with international outreach. ARCADE uses a dual approach to identify and overcome bottlenecks and in parallel maximise consensus and synergy between stakeholders. Using a road metaphor, ARCADE focusses on “removing road blocks, paving the road, prevent traffic jams and providing navigation to a common destination”. In an annual cycle, ARCADE positions the CAD Network (WP2) centrally which brings together the CAD community at national, European and International levels. The Thematic Areas (WP3) work on content creation leading to consensus-based positions, needs and scenarios. The Knowledge Base (WP4) consolidates the CAD knowhow baseline and serves as public one-stop shop overview of CAD.The main results of ARCADE will be:· Knowledge Base on CAD regulations and policy, on organisations & projects, on standards, on testing methodologies & data and lessons learned· Scenarios, positions, gap analysis and recommendations on 12 thematic CAD areas· Updates of CAD roadmaps· Common Research & Innovation approaches across EU, US, Japan and other countries involved· Web and news flash promotion of national, European and international CAD activities


**Keywords:** Network, knowledge sharing, exc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Synthesis of Systematic Resources' in the context of a Seventh Framework call.

assistant: **Objectives**

SYNTHESYS IA will aid in the evolution of a European resource through the creation an accessible, integrated infrastructure for researchers in the natural sciences in Europe and globally. By focusing the JRA on DNA extraction, SYNTHESYS IA will increase the opportunities for Users to exploit a largely untapped facet of the 337 million strong collections.  Users will be able to play an active role in generating new knowledge based on molecular and morphological studies. A range of new services and improved access – both physical and digital – will be provided to a broad range of scientific Users (from biological and geological related disciplines) in a consistent and more easily accessible way.   The new tools to be developed and disseminated will give Users the chance to pursue new avenues for independent studies at the leading edge of biodiversity and environmental research.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Eukaryotic unicellular organism biology – systems biology of the control of cell growth and proliferation', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The overall objective of UNICELLSYS is a quantitative understanding of fundamental characteristics of eukaryotic unicellular organism biology: how cell growth and proliferation are controlled and coordinated by extracellular and intrinsic stimuli. Achieving an understanding of the principles with which bio-molecular systems function requires integrating quantitative experimentation with simulations of dynamic mathematical models. UNICELLSYS bring together a consortium of leading European experimental and computational systems biologists that will study cell growth and proliferation at the levels of cell population, single cell, cellular network, large-scale dynamic systems and functional module. Building computational reconstructions and dynamic models will involve different precise quantitative measurements as well as complementary approaches of mathematical modelling. A major challenge will be the generation of comprehensive dynamic models of the entire control system of cell growth and proliferation, which will require integration of smaller sub-models and reduction of complexity. Implementation of the models will allow observing responses to altered growth conditions zooming in seamlessly from populations consisting of cells of different replicative age and cell cycle stage via genome-wide molecular networks, large dynamic systems to detailed functional modules. Employing computational simulations combined with experimentation will allow discovering new and emerging principles of bio-molecular organisation and analysing the control mechanisms of cell growth and proliferation. The project will deliver new knowledge on fundamental eukaryotic biology as well as tools for quantitative experimentation and modelling. Detailed plans for dissemination and exploitation will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Improving quality and safety of hen eggs in new production system by reinforcing the antimicrobial natural defence and by developing tools for grading eggs.' under Fifth Framework.

assistant: **Concept**

An egg is a pre-packed food that is vulnerable to external microbiological loads. Eggs are the major cause of Salmonella food poisoning in man. The mechanical protection afforded by the eggshell barrier and the antibacterial properties of membranes and egg white are influenced by several factors. These include physiology, genetics, and housing systems of the hen and storage conditions of the egg. Together they determine the potential infectious risk for humans. It is proposed(1) to analyse and measure the variation in these factors(2) to develop a mathematical model to predict the microbiological risks due to these factors(3) to genetically improve the egg's defence systems (eggshell/albumen)(4) to develop novel, real time, non-invasive grading systems and eliminate unsafe eggs(5) to define the optimal egg laying and egg storage conditions for alternative systems, which legally must replace battery cages in Europe by 2012.This project aims to guarantee the safety and quality of eggs to consumers in new production system respective of hen welfare and to improve UE competitiveness favouring employment.