RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Impact of maternal nutritional status and microbiota on child anthropometric and metabolic development' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Both overnutrition and undernutrition shape the capacities of the body to process food (double burden of malnutrition), and are thus important determinants of metabolic syndrome, a cluster of conditions including high blood sugar or excess body fat, and diet-related diseases such as type 2 diabetes or heart diseases. The first 1000 years of life (from conception to second birthday) are considered a key period of life where the metabolic capacities are adjusted. We hypothesize that during this period, exposures such as the nutritional and metabolic status of the pregnant mother, her gut and vaginal microbiota, the child’s gut microbiota and other clinical parameters linked to pregnancy, delivery and early life, have an impact on how the metabolism develops. The objective of the proposed research is to study the contribution of prenatal/early life exposures on the anthropometric and metabolic development of the child, and whether these effects could be mediated by epigenetic changes. For this, I will spend 24 months in the University of Lausanne, Switzerland, for the outgoing phase (Prof. Pascale Vonaesch) followed by a returning phase of 12 months in FISABIO, Spain (Dr. Pilar Francino). This collaboration gives me the unique opportunity to work on samples and data from two birth cohorts of under-, normally and over-nourished pregnant mothers and their offspring, both in a low and a high-income country (Lao PDR and Spain). I will bring my expertise in epidemiology and clinical research, as well as specific knowledge and skills in analysing vaginal microbiota data, to the host and associated partner. In return, I will dig into new concepts and acquire advanced skills in genomics (from bench work to bioinformatics), community analysis, epigenetics, nutrition-related disease
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'beSCIENCEd - Bringing science and research directly to the young people' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

The main goal of beSCIENCEd is to bring the general public and especially young people closer to the exciting world of research and to show that science is fun and accessible for everyone. Scientists from almost all significant research institutions in Vienna are going to participate in the event and present their recent research results in order to generate enthusiasm among young people for science and research. A focus is laid on the fields science, technology, engineering and mathematics (STEM) and the exiting topics cover informatics, mobility, energy, construction, biology, chemistry, mathematics, and automation. Thus, it is shown how broad research can be. Every topic can and will be looked at and interpreted in a different ways and our program is going to cover all these aspects. The beSCIENCEd program will integrate researcher talks, hands-on workshops as well as a range of ongoing activities by the exhibitors and social activities like science cafes where visitors can get in direct touch with scientists and their research. To increase the interest of more young people in research careers, also the opportunities of research during the school time will be shown by the presented projects of the Austrian Sparkling Science initiative as well as by the projects of student researchers active in various research projects. Moreover, to encourage entrepreneurial thinking of young people, a few Viennese innovative start-up companies are going to present their innovation and business cases. To grasp technology with own hands, a series of workshops is provided for different age groups. The social events are aimed at showing that researchers are ordinary people with extraordinary jobs and that research is also much about communication and international cooperation. As the ev
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Mechanisms by which interfacial layers control lipolysis on digestion' (LIPOGEST) targeting Seventh Framework.

assistant: **Abstract**

Obesity is a major health problem in the EU and levels are currently increasing. A strong correlation exists between dietary fat intake and obesity, contributing to increased incidences of cardiovascular disease, diabetes and some cancers. These related conditions have a hugely detrimental impact on the quality of life of the sufferers and also on national health care resources, currently estimated at 5% of the EU’s total healthcare budget.  There is a need to better understand the effect of the complex interfacial structures that stabilise emulsions on the mechanisms involved in the breakdown of fat by lipases (Lipolysis). Lipase and its cofactor colipase have to adsorb on to the surface of fat droplets, in order to access and hydrolyse fats into their constituent components, so that they can be absorbed by the body. Processed food emulsions are stabilised by complex interfaces composed of proteins, emulsifiers and lipids. Lipase action is very sensitive to interfacial composition. We have shown that bile salts can displace the protein networks, but the extent to which interfacial structures are degraded during digestion will determine how quickly lipid is broken down and digested. By slowing down lipid digestion is thought that we can induce feelings of satiety and reduce subsequent dietary fat intake by reducing appetite.  The intention is to determine how the physiological conditions in the stomach and the duodenum change the structure of these interfacial layers, including synergistic/cumulative effects. Then to correlate these interfacial structures with rates of breakdown of fats by lipases. This information will be obtained using state-of-the-art interfacial biophysics methods and unique probe microscopy techniques for imaging interfacial structure. The improved
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The chickpea protein revolution – a novel plant-based food ingredient' (CHICKPRO70).

assistant: **Concept**

InnovoPro has developed a new protocol enabling the commercialisation of chickpea protein as a new food ingredient (patent US 2013-0196028). We expect this product to take a relevant share of the growing plant-based protein market which is expected to reach a market size of USD 7.14b by 2021. The chickpea protein provides the food industry with a unique protein source which can easily be integrated in food products, reduces or removes for the need for various emulsifier and other artificial ingredients and is highly environmental friendly. This makes the chickpea protein an alternative for artificial emulsifiers and alternative for the heavily used soy protein which, amongst others is a GMO crop. InnovoPro can also compete with pea protein which is becoming more popular but has drawbacks which make integration in food more difficult. We expect the commercialization phase of the InnovoPro chickpea protein to start in 2019, when the product will be launched as a premium ingredient. We have the attention of leading European food producers several of which are currently testing our samples and developing prototypes of food products with “InnovoPro inside"".  Our operational team is highly experienced as is our board and circle of external advisors and we aim to use this SME Phase 1 project to further organize the work with our existing test-clients, develop a detailed scale-up plan, professionalize our market research and lead identification and, last but not least, organized our (financial) business planning to support our expected market entrance and growth from 2018 through 2023. ""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The Causal Effect of Public Policy and Income on Child Health and Human Capital' under Horizon 2020.

assistant: **Concept**

A recent literature in economics on the “fetal origins hypothesis” has documented that a range of early (prenatal and postnatal) shocks and interventions can have substantial effects on long-term human capital formation (e.g. adult health, wages). However, we still know little about the years in between early infancy and adulthood, referred to as the “missing middle”. How do early shocks affect health and human capital formation during childhood? How do the effects of different types of interventions, or shocks at different ages, compare? What are the most cost-effective ways of improving young children’s future outcomes?I aim to fill this gap in the literature by taking advantage of a range of natural experiments in a country, Spain, for which high quality administrative data are available for the past 35 years. State of the art econometric techniques, combined with large sample sizes, will allow me to evaluate credibly and precisely the causal effects of a number of different public policies and shocks on child development. I will consider five different “shocks” in early childhood (at different ages), affecting: i) Household material resources (an unconditional mother’s allowance); ii) Parental time (subsidized paternity leave); iii) Medical treatments around birth (elective delivery); iv) The availability of family planning services (access to abortion); and v) Aggregate demand shocks to different sectors of the economy.I will evaluate their impact on health and cognitive development at ages 0-15, as measured in hospital and primary health care records, school grades, and standardized test scores, among other data sources. I will also study the potential channels linking treatments to child outcomes, including family size (fertility), parental time use and labor mar
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Creative Activisms towards Material Intersectionality in Water Conflicts: Expanding the Visual Field' under Horizon Europe.

assistant: **Concept**

Legibility is at the center of intersectionality. It is common to find phrases such as “to make visible” certain forms of oppression as the main objective of intersectional studies. Its legal roots and inclusive potential lead to an increasing presence of the term and percolated human rights instruments. However, its use remains discursive and the attempts to operationalize the concept still replicate the “rights-bearing-subject” paradigm and hold on to identitarian categories. MATERIALITIES will contribute to materialize the “intersectional exposure” approaching visibility debates creatively by following a different strategy than that of creating the legal category of a subject in order to see them. Through new materialisms framings and using ethnographic approaches and vibrant audio-visual methods on four case studies from Argentina (1) and Spain (3), MATERIALITIES will consolidate a novel theoretical and operative framework about intersectionality in rights-based interventions in water conflicts. The trainings and transfers of knowledge focus on advocacy using creative activisms, innovative qualitative research methods, experiential or clinical teaching, networking and novel synergies, leadership and science communication skills. In addition, the guidance of Beatriz Rodriguez-Labajos, a leading scholar on the matter, at UPF, and Laia Forné Aguirre during a secondment at IDRA -a think-tank known for its strong links with grassroots organizations and experience in network practices- they all contribute to a project tailored for merging human rights advocacy and creative activism that will lead to an intersectional legal framework grounded on empirical approaches to water related conflicts and expanded by creative activisms. MATERIALITIES impact stands out for promoting
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Remote Home Monitoring of Patients' under Fifth Framework.

assistant: **Concept**

The @HOME project aims to enhance patient welfare and quality of life across the EU. The project introduces next-generation, user-friendly, cost-effective and interoperable general-interest health services by ensuring hospitals make best use of state of the art technology in communications (UMTS, Bluetooth, data privacy and secure connections) and ubiquitous medical sensors. The @HOME system is primarily addressed to European hospitals and their patients. It is envisaged as a post-stationary application, i.e. it will come into play once the patient has received hospital treatment and is recovering. During the recovery phase, the patient is often hospitalised in order to monitor critical, but often simple to measure, parameters, such as temperature, blood pressure, pulse rate etc. Another parameter which is of interest and which will be investigated is treatment compliance. The objective of the project is to equip clinics with state of the art infrastructure, which will allow for continuity in patient treatment at home and, often, a faster dispatch of patients. By the end of the project, the @HOME platform will enable hospitals to perform remote regular and reliable health monitoring of patients residing and recovering at their homes and will promptly advise the clinic staff in case of an emergency. Reciprocally, @HOME will provide information services regarding the recovery of the patients to the patients themselves and their carers/ relatives. Finally, the system will be validated via clinical trials on two pilot projects.Objectives:The @HOME project will produce a robust platform for real-time remote monitoring of patients at their home by their doctors at the hospital. @HOME will be addressed to two patient groups and their doctors: patients recovering after hospital
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Aberrant Splicing of CFTR Exon 9' (ASCE), addressing dissemination and exploitation.

assistant: **Impact**

Alternative splicing of pre-mRNAs is tightly regulated and any imbalance can change the outcome of gene expression which often leads to disease. Despite the importance of alternative splicing regulation our knowledge at the molecular level is still in its infancy hampering development of effective therapies. We plan to study the regulatory RNA-protein and protein-protein interaction networks leading to skipping of CFTR exon 9 associated with severe forms of cystic fibrosis. Structure determination of regulatory complexes by NMR spectroscopy in combination with biochemical and functional in vivo studies will be used to deepen our molecular understanding of the regulatory networks governing the proper assembly of mRNAs. With this, we want to reveal the molecular basis of aberrant CFTR exon 9 splicing and lay a rational, structure-function-based foundation for novel approaches to cure diseases.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Imitation of movements as a step towards the development of artificial social intelligence for autonomous robots' to be submitted under Fourth Framework.

assistant: **Abstract**

The project's main objective is investigating the development of artificial social intelligence for autonomous robots. The scenario consists of an imitating robot, copying other robots' movements. This should enable the robot (1) to identify other individuals in the group in order to allow specific complex social interactions, and (2) to learn new movement patterns. The project should elicit the basic requirements and constraints which are necessary for implementing imitation capabilities in a group of robots. This covers the whole range from theoretical investigations to technical work (design of the robots and of the environment), conceptual work (developing control architectures) up to implementation, test, and documentation of the experiments. The 'artificial social intelligence approach' to developing intelligent artifacts is a new and highly interdisciplinary research direction which contrasts mainstream approaches in artificial intelligence, artificial life and robotics. The results should point out a new direction towards building intelligent artifacts.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The Neural Underpinnings of Childhood Adversity' (NUCA).

assistant: **Concept**

Experiences of childhood adversity are major risk factors for subsequent vulnerability to psychopathology. Although research suggests that specific brain regions are particularly sensitive to childhood adversity, the mechanisms that underlie these associations are yet to be elucidated and it is unclear how widespread connectivity networks contribute to this vulnerability phenotype. This project aims to determine the functional connectivity networks in the brain that bare the signatures of negative experiences and the neuroendocrine mechanisms that facilitate such alterations. To achieve this, we propose two studies utilizing data from the UK Biobank. Study 1 will investigate the resting state networks associated with early adversity. This study will benefit from the statistical advantages of ""big data"". It will be the first analysis of this magnitude looking at the interplay between early life events and neural networks. Study 2 will characterize the inter-individual variations in adversity-related functional changes, by addressing the moderating effects of glucocorticoid-related genetic variants that increase biological vulnerability. This study will contribute innovatively to the state-of-the-art in the emerging field of imaging genetics. This research uses advanced statistical strategies for neuroimaging analysis of an unprecedented number of scans and use of innovative analysis infrastructures under the FAIR principles. Furthermore, it is strongly multidisciplinary, involving a combination of psychological theory, neuropsychology, neuroimaging, machine learning and genetics. This action will involve end-users in all implementation stages, with the aim to engage the public in science education, raise awareness of stress-related consequences and the need for widespr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Hypertext/hypermedia, interactions and learning - analysing the effects of hypertext/hypermedia on social inter-actions in learning situations' (1994-1998) under Fourth Framework.

assistant: **Objectives**

This request fits into the frame of a thesis of an ongoing doctorate. The aim of this piece of work is to light up the links between the new communication technologies and learning, or else, between the communication on in its technological view and the communication in its pedagogical view. The concrete aim of this research is focused on hypertexts and hypermedia. The central question of this research can be defined as followed: What significant difference, what specific change can a communication technology as hypertext or hypermedia induce in social interactions between subjects involved in learning situations ? In other words, how can this type of technology affect the communication between the actors concerned by its use in learning situation ? And by the way, how can it affect the building up of knowledge itself ? In this frame, the specific objective of the research planned at the University of Paris Vlll is double: - first, to strengthen the theoretical and methodological frame of the project, in connection with the researchers and teachers of this University working in the fields of educational technologies and hypermedia; - second, to participate with them to the observation, analysis and evaluation of concrete hypermedia systems, concerning their effects on social interactions in learning situations.