RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Walking the tightrope between life and death: Oxygen homeostasis regulation in the nematode Caenorhabditis elegans' (WTBLDOHRNCE).

assistant: **Innovation**

Oxygen (O2) is vital for the life of all aerobic animals. However, fine-tuned regulation of O2 levels is crucial since both shortage (hypoxia) and excess (via the production of reactive oxygen species, ROS) may be harmful. Indeed, both hypoxia and ROS may underlie the pathophysiology of many diseases such as atherosclerosis and Alzheimer’s. To understand how this fine-tuned O2 regulation is achieved at both the molecular and organismal levels my research proposal aims to explore the following integrated questions, using the nematode C. elegans as a model organism.1)How do animal sense O2? What are the molecular sensors and how do they act together to fine-tune O2 responses?2)How does O2 regulate food intake, and repress appetite in hypoxia?3)How do animals survive and behaviorally adapt to hypoxia without HIF-1?4)How hydrogen sulfide (H2S) regulates O2 responses and aging?5)How do animals protect against mRNA oxidation damage?I have focused my research on the globins. GLB-5 is a C. elegans hexacoordinated globin that regulates foraging behavior in response to subtle changes in O2 concentration. Like neuroglobin and cytoglobin in our brain, GLB-5 is expressed in neurons. Recently I discovered that GLB-5 regulates the re-adaptation of animals to 21% O2 after hypoxia. To understand how GLB-5 regulates hypoxia-reoxygenation responses I made a mutagenesis screen and isolated four classes of GLB-5 suppressors, and mapped them using single-nucleotide polymorphisms (SNP’s) to about a 1 Mbp genomic interval. Using a novel non-PCR based libraries preparation and Next Generation whole-genome sequencing, I have already sequenced four independent mutations and cloned one of the GLB-5 suppressors. In the future, I intend to clone more suppressor genes, and use this methodology in oth
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Supporting the development of a European solar thermal technology roadmap'.

assistant: **Innovation**

The SecESTTP project is a Specific Support Action (SSA), which will set up a supporting structure called Secretariat" for the European Solar Thermal Technology Platform (ESTTP). The aim of the Secretariat (SecESTTP) is to support the different entities of the ESTTP by providing organisational support and information to the steering committee and working groups and ensure a smooth functioning of, and between these groups.The ESTTP aims at bringing together relevant stakeholders, mainly from R&D, solar thermal industry and the buildings sector, but also from policy, finance and other interested groups in order to develop the European Solar Thermal Technology Roadmap. This roadmap will comprise of:- European Solar Thermal Outlook 2030- Strategic Research Agenda for the solar thermal sector - Reports on the solar thermal sector"s needs in terms of market deployment and framework conditions: - Research infrastructure - Skills and training - Raw materials and components"
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Targeting leukaemia by modulating hematopoietic stem cell competitiveness' (Hemstem), addressing dissemination and exploitation.

assistant: **Impact**

Human acute myeloid leukemia (AML) remains a devastating disease with less than 30% of patients surviving five years after diagnosis. Despite decades of research and detailed mo-lecular insights provided by mutational profiling, curative treatment still requires high-intensity chemotherapy and the crude approach of allogeneic stem cell transplantation – an effective, yet non-specific immunotherapy that is costly to the patient because of its severe side effects. One reason why the wealth of molecular and experimental knowledge has so far been unable to revolutionize treatments is the fact that AML is driven by small subpopulations of so-called leukemic stem cells (LSCs), which survive chemotherapy and immune surveillance. LSCs have growth advantages induced by oncogenic mutations, but are in many ways similar to healthy hematopoietic stem cells (HSCs). This similarity makes it difficult to target LSCs without simultaneously eradicating HSCs and healthy hematopoiesis derived from these cells. Like HSCs, LSCs home to protective bone marrow (BM) niches promoting stemness and therapy resistance and modify them to displace HSCs and promote their own expansion. This proposal explores strategies to target LSCs based on understanding these interactions. In Aim 1 we investigate how WNT signaling, an evolutionary conserved pathway governing stem cell self-renewal, regulates interactions between leukemic and healthy hematopoietic (stem) cells. In Aim 2, we propose to inhibit the in vivo expansion of LSCs by enhancing self-renewal and niche affinity in their natural competitors, the healthy stem cells with inborn BM homing ability. Aim 3 uses zebrafish to visualize LSC-HSC interactions and screens for molecules supporting healthy instead of (pre-) malignant hematopoiesis. Our studi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Interactive and Accessible Sign Language Translation - AccessibleTranslation' to be submitted under Horizon 2020.

assistant: **Abstract**

Deafness  and hearing impairment are conditions in which an individual has very little or no hearing or the inability to hear as well as someone with normal hearing. It is estimated that over 5% of the global population , suffers from disabling hearing impairment. Moreover, nearly 15% of the global adult population is affected by some degree of hearing loss. Majority of which is found in the less developed nations. The most used way of communication  is the sign language that comes in many forms, there are over +200 sign languages (ASL, BSL, FSL, etc.) in use around the world today, three categories of sign languages: 1) Deaf sign languages – the main language of deaf communities; 2) Auxiliary sign languages; 3) Signed modes of oral languages (known as manually coded languages). Another way of communication is to use an interpreter (Or remote VRS interpreter) to communicate with a hearing person, whichis not instantaneous as you have to book the service online or you have to hire one.Our innovative solution: AccessibleTranslation aims to permanently solve the communication problem of deaf and hearing-impaired people in their daily life. They will be able to handle their work without the need of an interpreter, a sign language speaker or trained staff in sign language. Our platform provides a real-time captioning, it captures and translates sign language into audio, it also transforms audio into sign languages, and it also translates text into sign language. It can be easily integrated in different platforms. We now aim to introduce our patent-pending solution to the assistive technologies market across Europe as initial target market and worldwide seeing how our solution offers significant communication performance and improvements and is market disrupting in its potent
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'European Concept of operations for Higher airspace  Operations' to be submitted under Horizon 2020.

assistant: **Abstract**

The Higher Airspace region is located between the airspace normally used by aircraft and the beginning of space. Higher airspace is no longer an exclusive transition zone, but an area where operations will be significantly expanded as a result of the emergence of a complete new aviation domain, business and technical opportunities and more, representing business values in the order billions per year. The anticipated operations in the Higher Airspace represent an emerging market like for the early days of aviation where providing rules, including structural procedures regarding traffic and operations management, is now considered as the key enabler of this international healthy business of  $900b/y which worldwide connect people and civilisations.The ECHO (European Concept of Higher airspace Operations) Project will deliver a comprehensive demand analysis and a comprehensive, innovative and feasible Concept of Operations enabling near term and future Higher Airspace operations in a safe and orderly manner.  The Higher Airspace including the operators forms a new, almost legacy free environment enabling an expeditions uptake of innovations or, extrapolated SESAR solutions. In this way the Higher Airspace could become an incubator environment for future ATM. The ECHO project deliverables will also be instrumental in developing a Global performance based framework and will be the basis for the European Regulatory Framework.  For this the project includes all the key European actors and includes extensive coordination and consultation activities, such as three large Thematic Work Shops, to ensure wide European Stakeholder buy-in and alignment with evolving European policies.The project will pave the way for the economic development of various commercial concepts that will on
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The politics of anti-racism in Europe and Latin America: knowledge production, decision-making and collective struggles' (POLITICS), addressing dissemination and exploitation.

assistant: **Impact**

The main objective of POLITICS is to innovate knowledge on anti-racism that brings about a greater understanding of how historically rooted injustices are being challenged by institutions and grassroots movements. Considering the centrality and mutual influence of Europe and Latin America in the global processes of racial formation, POLITICS will develop an inter-disciplinary and comprehensive approach towards two core goals: (a) the analysis of processes of knowledge production about ‘race’ and (anti-)racism in the spheres of (inter)national governmental politics, State universities and grassroots movements; (b) the examination of diverse paths of denunciation and collective mobilisation against everyday racism concerning police practice and representations in the mass media. POLITICS embraces a multilevel analysis and information-oriented selection of case-studies in three interrelated research streams: (i) Global, regional and state-sponsored political frameworks and public policies; (ii) Cultures of scholarship and the study of racism and (post)colonialism at State universities; (iii) Tackling everyday racism: processes of denunciation, political mobilisation and case-law concerning police practice, and racist representations in the media and mass media. The research challenges the shortcomings of evaluative comparisons and the selection of research contexts enables interrogating the relations between the global, national and local levels. They include the Organisation of American States, the European Union and national and local politics in Brazil, Peru, Portugal and Spain. Qualitative research and data collection engage with race critical theories, critical discourse analysis and participatory methods that consider power/knowledge at their core. POLITICS will unra
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'African small mammal symposium: international workshop on ecologically based field rodent pest management.'.

assistant: **Objectives**

In the frame of the STAPLERAT project (ICA4-CT2000-30029), research is carried out on Protecting staple crops in eastern Africa: integrated approaches for ecologically based field rodent pest management". This project combines basic scientific research in rodent biology with the study of new technologies for rodent control. Due to the regional scale, a wide relevance of the obtained results is obvious. Towards the end of the project, in July 2003, an international workshop will be organised in Tanzania, to present the results of this project and link up with similar work elsewhere. This workshop will be integrated with the African Small Mammal Symposium, guaranteeing a wide international interest and attendance. This proposal will financially assist scientists from other developing countries to attend the workshop and allow publication of workshop proceedings."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Olefin metathesis - application to synthesis of bioactive medium and macrocycles natural products' (1994-1998).

assistant: **Innovation**

Research objectives and content Applications of ring closing metathesis methodologies for the synthesis of important moisture macrocycles. The Prof. Dr. Furstner's group has the experience in Olefin Methatesis chemistry, as well as in organometallic chemistry to use a good tool for the development of this project. Training content (objective, benefit and expected impact) My research will involve catalytic organometallic chemistry, as an useful tool to the synthesis of medium and macrocyclic compounds with industrial or pharmacological activities, adquiring a good formation in the area of catalytic synthetic chemistry. Therefore, this can have an important impact in my potential future in research in Spain. Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Euroreg', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

This EuroConference will focus on the impact of European integration on regional convergence, location of industrial activity and labour markets adjustment in both EU member states and accession countries. The overall objective is to bring together established and young researchers as well as policy makers and discuss issues of actual importance in both current and future European Union member states such as:a) Patterns of regional specification, regional disparities and regional convergence/divergence at European and national levels;b) European integration, location and re-location of industrial activity; c) Regional labour markets adjustments; d) Regional policy in the context of EU enlargement. This conference will contribute to a better understanding of the structural changes at regional level in Europe and regional implications of the European Union's eastward enlargement. In particular, this conference will foster the creation of a network of researchers in the area of regional development from current EU member states and accession countries.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'MOORING SYSTEM INTEGRITY MANAGEMENT THROUGH MONITORING, DIGITAL TWIN AND CONTROL TECHNOLOGIES FOR COST REDUCTION AND INCREASED EFFICIENCY' (MooringSense).

assistant: **Innovation**

The project MooringSense aims at reducing operational costs and increasing efficiency through the development of an efficient risk-based integrity management strategy for mooring systems based on an affordable and reliable on-line monitoring technology. The proposed solution will be enabled by the development of a low-cost smart sensor for FOWT motion monitoring, a Mooring System Digital Twin (DT) model, Structural Health Monitoring (SHM) techniques, as well as control strategies for mooring condition management tolerance at turbine and farm levels.The monitoring technology proposed will replace the existing unreliable and expensive monitoring systems based on load cells in the mooring lines by a combination of a robust motion sensor and numerical models. In addition, measurements will enable the development of more efficient operation and maintenance strategies, including optimized control.MooringSense’s consortium strength covers the full value chain, with a proven track record in the Offshore Wind and Oil and Gas Industries, and supported by experienced research institutions, the project will start from current partner’s technology to develop an innovative cost-efficient mooring integrity management enabled by Global Navigation Satellite System technology, coupled numerical modelling, control engineering and machine learning, with both increased efficiency of the overall resulting system as well as reduced operational expenditures, when compared with known incumbent alternatives.


**Keywords:** Offshore wind energy, OPEX, Mooring System Digital Twin, Digital Twin modelling, Structural Health Monitoring, Smart Sensors, Global Navigation Satellite System, SHM Algorithms
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'DEVELOPMENT OF NOVEL AND ROBUST MOLECULAR IMPRINT-BASED TECHNOLOGY FOR THE REAL-TIME ANALYSIS OF FOOD CONTAMINANTS AND COMPONENTS' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Highly selective and robust MIPs have been developed for ß-lactam antibiotics and clenbuterol. The results of the study indicate that MIPs can be used to prepare both selective and general recognition matrices for either individual analytes (e.g. penicillin) or groups of compounds (e.g. the ß-lactam antibiotic group). The MIPs developed have shown very good reproducibility and stability.Practical protocols for the use of the MIPs as solid phase selective absorbents for the analysis of food samples have been developed and briefly evaluated. Specific MIP-based separation of clenbuterol from meat and kidney, and of a ß-lactam antibiotic (oxacillin) from milk, has been shown. Independent evaluation of the clenbuterol MIPs by the European MICA Network Group also demonstrated good reproducible performance.The MIP developed for clenbuterol has been successfully used to prepare a novel sensor comprising MIP as the selective element and amperometric detection as the transducer. The responses from several such sensors were measured to be reproducible within a variability of 10%. The feasibility for an oxacillin MIP-based sensor has also been shown in a limited investigation, promising results have also been achieved in the bulk polymerisation studies which has the scope for progress towards commercial production of MIPs. This is important, as the classical laboratory-based techniques are wholly unsuitable for large-scale production of MIPs.Two patent applications (e.g. concept for microbial MIP production and the scale-up procedure mentioned previously) are under active consideration and a wide dissemination of all the non-proprietary information in papers and presentations has been made.Measurement of the type and concentration of viable microorganisms in foodstuffs is currently