RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Towards faster super-resolution DNA optical mapping using plasmon-enhanced fluorescence' (2021-2027).

assistant: **Innovation**

Human microbiome science is advancing, showing promise of having important impacts on human health with new insights into disease etiology and general human biology. Accordingly, DNA sequencing platforms have been developed rapidly, expanding the scope in microbiome research. Among others, optical mapping technique, capable of imaging single DNA molecules provides access to genetic information on single molecules up to ~1 Mbp in length. It uses fluorescence imaging of linearly stretched DNA molecules labelled at specific sites to probe information patterns along the molecules. The precision of the method is further improved by resolving single molecules below the diffraction limit through super-resolution imaging. However, requirement of large photon budget slows down the speed of imaging, as long acquisitions are required to build up sufficient photons for precise localization. This affects the throughput of DNA optical mapping which involves imaging large areas, thereby limiting its capabilities in providing real-time information of the microbiome on daily basis. Enhancing the emission rates from single molecules can overcome this limitation to permit faster image acquisition. Here we propose to use plasmon-enhanced fluorescence by employing substrate made out of wet-chemically synthesized gold nanotriangles for optical mapping of human gut microbiome. Plasmonic nanostructures can confine incident electromagnetic field into small area near their surface leading to strong light absorption and higher emission rates from fluorophores in their vicinity. The use of wet-chemical plasmonic substrate exhibiting strong plasmon resonance can significantly increase the number of photons released from the labelled DNA, allowing faster image acquisition. With the improved speed, t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Reconstitution of the basic molecular mechanism of phagocytosis – a bottom-up synthetic biology approach'.

assistant: **Concept**

The ability of cells to engulf large objects, such as invading microorganisms or apoptotic cells, is crucial to innate immunity and tissue remodelling. The molecular basis of this process - phagocytosis - is complex, involving numerous receptors and signalling pathways. Nevertheless, the biophysical process is always the same: the cell membrane deforms and reshapes to wrap around the particle, and upon closure and abscission of the resultant cup, the particle is internalised. Although the key molecular players in individual phagocytic pathways have been identified, we still know very little about the basic biophysics common to all phagocytic pathways. I propose to fill this gap in our knowledge by creating a “minimal phagocyte”: I aim to reconstitute a minimal, dynamic actin cytoskeleton and artificial phagocytic receptors in giant unilamellar vesicles (GUVs), thereby identifying the molecular components that are not only necessary but also sufficient for phagocytosis. Using synthetic biology to build a bottom-up model of phagocytosis should answer many open questions, including: are spatial cues resulting from particle binding required for membrane wrapping around the particle? Is directed initiation of actin polymerisation sufficient to render GUVs capable of phagocytosis? What is the role of the membrane-supporting actin cortex and how does the affinity of the receptors affect the engulfment process? Beyond phagocytosis, the minimal-model approach I propose will also be useful to study other cellular functions requiring actin-driven membrane reorganisation, such as cell mobility. In line with the objectives set by ERA-NET ERASynBio and the Horizon 2020 work programme (which identified synthetic biology as one of the “cutting-edge biotechnologies as future innovation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Digital Flows: Analysing Digital-Native Hip-Hop Culture' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

DIGITAL-FLOWS is a groundbreaking investigation of digital-native hip-hop culture, imparting new insights to European policy areas concerning Internet use, education, social equality, the creative economies, and connected communities. The overarching aim is to uncover and analyse the dynamic cultural politics of hip-hop music and community on the Internet, with three specific objectives: to design and apply a groundbreaking web-oriented, two-part methodology of data-driven and case-study research into online cultural networks; to apply musical, thematic, and political/feminist/critical race analysis to digital data objects (music, video, text) as expressions of hip-hop culture, politics, and aesthetics; and to generate conclusions on European priorities concerning online cultural expression, engagement, and education for sharing with policymakers. Among hip-hop's vast international listener base are many young and/or marginalised individuals, with unanswered questions about safety and security, communal opportunities, and wellbeing benefits of interaction with hip-hop's diverse and dynamic cultural expressions online. DIGITAL-FLOWS pioneers new approaches to these questions, generating high-impact outputs for academic and target audiences and policy recommendations concerning Internet use, education, and integration. The project will set a new benchmark in interdisciplinary studies of digital-native culture and provide a transferable model for web-oriented studies of popular culture more broadly. The research takes place in association with the CIPHER: Hip-Hop Interpellation initiative at University College Cork, an ERC funded team working in intersectoral collaboration with the Insight Centre for Data Analytics. Utilising UCC's CIPHER research network, DIGITAL-FLOWS' i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Gap Waveguides for Point-To-Point Wireless Links at 60 GHz and beyond' (GAP60PTP) targeting Horizon 2020.

assistant: **Abstract**

Our idea is to enable the next generation of mobile network infrastructure for high speed data communication through theuse of a new technology platform called gap waveguides. The demand for mobile data is growing rapidly and operators seetheir costs for mobile infrastructure rising. To meet the demand, and at the same time manage costs, the industry is lookingat an increased adoption of smaller, more cost-efficient mobile base stations (small cells) closer to the end-user. These areexpected to be connected wirelessly through high bandwidth point-to-point (PTP) solutions operating at 60 GHz and above.To be used at scale, these PTP solutions must fit into the city landscape, be cost-efficient, and easy to install. However,current radio frequency (RF) technology at 60 GHz leads to bulky and expensive products with poor performance as lossesincrease dramatically with frequency. Gap waveguides is a newly invented technology platform for constructing microwavecircuits, which has been shown to have inherently low losses.Our concept is to apply the gap waveguide technology to RF front-ends in PTP solutions. The objective with the proof-of-concept study is to understand the market need for an integrated 60 GHz RF front-end in more detail, and evaluatepotential mass production methods to verify the concept’s commercial viability. The study will be performed in four phases:(1) A pre-study capturing the current research status and detailing the project plan; (2) A market verification includingmarket, customer competitive analyses; (3) A mass production method evaluation to identify and evaluate potentialmethods for machining and assembly of gap waveguide based components; and (4) A definition of the way forwardsummarizing key findings, conclusions, drafting of plans for market ent
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Impact of Mental Training of Attention and Emotion Regulation on Brain and Behavior: Implications for Neuroplasticity, Well-Being and Mindfulness Psychotherapy Research.'.

assistant: **Innovation**

Mindfulness-based therapy has become an increasingly popular treatment to reduce stress, increase well-being and prevent relapse in depression. A key component of these therapies includes mindfulness practice that intends to train attention to detect and regulate afflictive cognitive and emotional patterns. Beyond its therapeutic application, the empirical study of mindfulness practice also represents a promising tool to understand practices that intentionally cultivate present-centeredness and openness to experience. Despite its clinical efficacy, little remains known about its means of action. Antithetic to this mode of experiential self-focus are states akin to depression, that are conducive of biased attention toward negativity, biased thoughts and rumination, and dysfunctional self schemas. The proposed research aims at implementing an innovative framework to scientifically investigate the experiential, cognitive, and neural processes underlining mindfulness practice building on the current neurocognitive understanding of the functional and anatomical architecture of cognitive control, and depression. To identify these mechanisms, this project aims to use paradigms from cognitive, and affective neuroscience (MEG, intracortical EEG, fMRI) to measure the training and plasticity of emotion regulation and cognitive control, and their effect on automatic, self-related affective processes. Using a cross-sectional design, this project aims to compare participants with trait differences in experiential self-focus mode. Using a longitudinal design, this project aims to explore mindfulness-practice training’s effect using a standard mindfulness-based intervention and an active control intervention. The PI has pioneered the neuroscientific investigation of mindfulness in the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Geochemical study of hydrated and dehydrated ultramafic rocks from the Cerro del Almirez (southern Spain): implications for element mobilization in subduction zones and the composition of arc magmas' (EMAS).

assistant: **Innovation**

In subduction zones, chemical elements are transferred between different reservoirs of the Earth (i.e., the atmosphere, the hydrosphere, the lithosphere and the asthenosphere) and important amounts of magmas are generated. Reactions involving volatiles are fundamental in mobilizing elements in subduction zones and they significantly influence the composition of the associated arc magmas, which show a characteristic enrichment in Large-Ion Lithophile Elements relative to the High-Field Strength Elements.There is an increasing agreement that one of the most important reactions that generates fluids in subduction zones and triggers the arc magmatism is the dehydration of antigorite serpentinite to prograde chlorite harzburgite.Here, I propose to carry out a detailed geochemical study of the ultramafic rocks from the Cerro del Almirez (southern Spain), which is the only natural example worldwide preserving the high-pressure dehydration of antigorite-serpentinite into prograde peridotite. Major, trace element and radiogenic isotopic analyses of whole-rocks and minerals from samples located across the serpentinite-harzburgite transition will be performed. This study will provide new insight into how lithophile and siderophile elements behave during the dehydration of serpentinite, how they are transferred between the different components of the subduction zone and how they influence the composition of the slab-derived fluids and arc magmas. This project will contribute to the transfer of knowledge of cutting-edge techniques on isotope analysis and to increase the international leadership of the host in the geochemistry of subduction zones, concurrently strengthening its cooperation with internationally-reputed European centres in Earth Sciences. The award of this reintegratio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Global ATM security management' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The GAMMA project stems from the recognition that while the SESAR initiative is effectively addressing some security issues in the new global ATM scenarios, there is a need to extend this scope to ensure a comprehensive assessment of the full set of security threats and vulnerabilities affecting ATM, considered as a system of systems and covering operational as well as technological aspects. In addition, there is a need, not completely met by SESAR, to establish a comprehensive framework for managing ATM security once SESAR deployment is engaged to minimise the effects of ATM crises brought about by security incidents.The GAMMA vision is to adopt a holistic approach for assessing ATM security, maintaining alignment with SESAR and reaching the following main objectives:- Extend the scope of threat assessment performed within SESAR to a more comprehensive system of systems level, inclusive of all ATM assets and all forms of threats.- Develop a Global ATM Security Management framework, representing a concrete proposal for the day-to-day operation of ATM Security and the management of crises at European level.- Define the architecture of an ATM security solution, suitable to support the security management of the global ATM system.- Design and implement prototype components of the ATM solution so as to demonstrate the functionalities and operations proposed for the future European ATM.- Set up a realistic validation environment, representative of the target ATM solution, through which to perform validation exercises aimed at validating the feasibility and assessing the adequateness of the procedures, technologies, and human resources issues proposed.GAMMA is strongly driven by the End Users present in the consortium supporting the project activities from the threat and vuln
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Analysing quarantine risks of alien agricultural pests: a case study' under Fifth Framework.

assistant: **Concept**

The quarantined maize pest Diacritical verifier will be used to investigate invasiveness of alien insects and key factors influencing establishment, spread and economic or environmental impact in European sustainable agriculture. This new information will be used in decision - making processes for containment and quarantine measures.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'On-shell renormalization of composite operators in o (a) improved lattice qcd' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

Research objectives and content It is proposed to apply recently developed non-perturbative techniques to the renormalization of composite operators which appear in effective Hamiltonians of the weak interactions. This project can be viewed as part of a general approach to the non-perturbative renormalization problem of QCD, based on numerical simulations and finite size techniques. As a result one may be able to determine various non-leptonic weak matrix elements to a good numerical precision and with controlled systematic errors. This is required for a better understanding of CP violation and to determine some of the fundamental parameters of the Standard Model of elementary particle physics. Training content (objective, benefit and expected impact) I expect to acquire or deepen my knowledge and technical skills in the following areas: 1) Perturbation theory, operator product expansions, renormalization group considerations 2) Monte Carlo algorithms for lattice QCD 3) Programming techniques on parallel computers 4) Finite size scaling techniques 5) Low energy phenomenology of weak interactions Links with industry / industrial relevance (22) The host institution is part of the APE1000 project in collaboration with Alenia Industry aiming at the construction of a 5 1 Teraflop parallel computer of the APE series.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Surface characterization of nano-particle embedded organic ionic plastic crystals and ionic liquid using advance 3D high resolution optical and electrochemical imaging' under Horizon 2020.

assistant: **Concept**

Soft, flexible electrode materials are needed for a variety of health and energy applications, e.g. nano-electrodes for bio-implantation and light weight electrodes for solar energy capture. Organic ionic plastic crystals (OIPCs), similar to ionic liquids (ILs), embedded with nano-particles (NPs) as reactive sites offer highly tunable solutions. OIPCs are also advantageous owing to a plastic phase that allows the conductive nano-plastic material to be molded at high temperature. However, the OIPC/NP field is in its infancy and little is understood regarding NPs stability/reactivity.By combining high resolution 3D optical imaging with electrochemistry, this project aims at mapping the NP reactivity and simultaneously correlate it to surface and chemical data based on NP density, from single NPs to collective or percolated films. New insights will be gained in the inherent chemical properties of composite materials as well as NP size, localization, etc. The synergistic interactions between NPs and ILs/OIPCs will be explored and exploited and will open new fields of research in materials science and optical imaging. Breakthroughs will include i) development of advanced plastic nanoelectrodes; ii) multiscale imaging (nm-µm) of innovative nanostructured electrodes.The experienced researcher (ER) will be trained in high resolution imaging techniques, while he is highly qualified to introduce the topics of IL/OIPC to the host laboratory. This new experience in optics, within the provided multidisciplinary scientific environment, will be an opportunity for him to complement to his current experience of chemistry. Dr. F. Kanoufi (supervisor) will also mentor the ER in course preparation and strategies through a teaching tribune. The ER will also conduct outreach events to the pu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Osteoporotic Virtual Physiological Human' (VPHOP) targeting Seventh Framework.

assistant: **Abstract**

Nearly four million osteoporotic bone fractures cost the European health system more than 30 billion Euro per year.  This figure could double by 2050. After the first fracture, the chances of having another one increase by 86%.  We need to prevent osteoporotic fractures.  The first step is an accurate prediction of the patient-specific risk of fracture that considers not only the skeletal determinants but also the neuromuscular condition. The aim of VPHOP is to develop a multiscale modelling technology based on conventional diagnostic imaging methods that makes it possible, in a clinical setting, to predict for each patient the strength of his/her bones, how this strength is likely to change over time, and the probability that the he/she will overload his/her bones during daily life.  With these three predictions, the evaluation of the absolute risk of bone fracture will be much more accurate than any prediction based on external and indirect determinants, as it is current clinical practice.  These predictions will be used to: i) improve the diagnostic accuracy of the current clinical standards; ii) to provide the basis for an evidence-based prognosis with respect to the natural evolution of the disease, to pharmacological treatments, and/or to preventive interventional treatments aimed to selectively strengthen particularly weak regions of the skeleton.  For patients at high risk of fracture, and for which the pharmacological treatment appears insufficient, the VPHOP system will also assist the interventional radiologist in planning the augmentation procedure. The various modelling technologies developed during the project will be validated not only in vitro, on animal models, or against retrospective clinical outcomes, but will also be assessed in term of clinical imp