RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Brain Interchange ONE SR—the implantable neuromodulation technology for stroke rehabilitation'.

assistant: **Innovation**

Electrical brain stimulation has been successfully used since the 1990s to treat neurological illnesses, particularly movement disorders. Most of the devices for this novel approach are based on the old pacemaker technology. Companies are unwilling to take device development risks & rely on established tech, limiting new therapy developments. Many neurological diseases are still treated with pharmaceuticals only, which has limited effectiveness and causes severe side effects. Neuromodulation—electrical stimulation research has increased in recent decades. Additional recording capabilities & closed loop therapy expand therapeutic options. CorTec aims to provide novel  implantable tech to overcome the current limitations: it enables researchers, medical institutions & industry to develop new therapies & devices. We plan to finalise the development of our tech for stroke rehabilitation, conduct clinical trials & get market approval in 2029, generating €250M in sales in 2030.


**Keywords:** therapy development,stroke rehabilitation,rehabilitation,plasticity,personalised treatment,neurological disorder,neurodegenerative diseases,neuromodulation,computational neuroscience,neuroimaging,Micro (system) engineering,Central Nervous System,AI
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The Resilience and Evolution of Economic Activism and the Role of Law' (REVEAL) under Horizon 2020.

assistant: **Objectives**

The global financial crisis put basic tenets of neoliberalism into question. Previous crises on product safety also exemplified the limits of delegating regulatory power. However, in the medium run, private regulatory bodies re-assume their previous powerful status and continue to exert undue influence on the functioning of economic activity.This research project investigates the origins and causes of the dominance of private rule-making bodies, focusing on their mutability and resilience. It does so by addressing the following research question: what enabling conditions, innate traits and mechanics allow for the transformation, adaptability and resilience of private rule-making bodies amid exogenous regulatory shocks and how does the law perpetuates this dominance?This project develops a multidisciplinary conceptual framework to analyse structures, institutional design and adaptive/resilience strategies in 10 non-public regulatory bodies and their public law counterparts. Data are collected via qualitative methods (interviews with key individuals, direct observations, historical institutionalism, process tracing) to identify trajectories of change and causation spanning three decades.This research is groundbreaking in three ways: (1) by delving into the peculiarities of private collective action, it sets the basis for a new theory of creation, evolution and resilience of such action; (2) by integrating multiple disciplines, it innovates methodologically and offers a multidisciplinary and thus more comprehensive theory of private action in the service of future generations of researchers and policymakers; (3) by collecting data and theorizing on a largely unexplored (from an empirical viewpoint) area such as transnational standard-setting, it revisits the promises, flaw
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'European modelling initiative combating complex diseases'.

assistant: **Objectives**

Primary targets of the Sixth Framework programme are activities for the development of advanced genomics and bioinformatics tools, their applications for health and for the combat of multigenic complex diseases. The understanding of biological processes relevant for these diseases and the modelling of these processes in silico is an essential step in the development of new drugs, medical diagnostics and therapies. Analytically, the modelling of disease processes is an integrative and multi disciplinary approach that has to cope with data from diverse functional genomics platforms such as gene expression and protein expression data, functional sequence data, physiological data, environmental factors and many others. The aim of the proposed project is to provide an adequate modelling and data integration platform that is able to manage the complexity and heterogeneity of these underlying data sources, and to generate hypotheses and models for disease processes based on in silico predictions. Ultimately, this platform will enable medical researchers to predict quantitatively clinically relevant parameters. The strategy to achieve these objectives is a platform technology that consists of benchmarking analysis modules including exhaustive data retrieval from databases, experimental data quality control and data integration, network analysis and expansion, kinetic modelling and simulation engines. The proposed project is a consortium approach Involving both key research institutes and SMEs in order to obtain a balanced mixture of scientific and industrial stakeholders. The project will provide an internationally competitive platform for the analysis and modelling of complex disease processes that will meet the requirements of post genomic research. This will ultimately stren
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Functions and evolutionary impact of transcriptomic novelties in the vertebrate brain' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Alternative splicing (AS) is the largest contributor to transcriptomic diversification in metazoans. In particular, mirroring their unparalleled morphological and cellular complexity, vertebrate brains show the highest levels of regulated AS known in nature. However, the functions of most of these alternative transcripts, and the evolutionary impact that the increased transcriptional complexity has had on the evolution of the vertebrate brain are still widely unexplored. In this project, we will investigate the functions and evolutionary impact of neural AS in vertebrates. We will focus on neural-specific alternative exons that are highly conserved across vertebrate groups (suggesting functional importance), but that are not conserved in invertebrates, and are thus vertebrate-specific genomic novelties. We will term these exons Vertebrate- and Neural-specific Alternatively Spliced (VN-AS) exons.Through a combination of bioinformatics, experimental manipulation in models species, and systems-level network analysis, we aim to: (i) Comprehensively identify VN-AS exons, and study their regulation during vertebrate neurogenesis and nervous system development, using RNA-seq and comparative genomics; (ii) Probe the phenotypic impact of VN-AS exons on vertebrate nervous systems, using the CRISPR-Cas technology for genome editing; and (iii) Investigate how VN-AS exons rewire protein-protein interaction networks in vertebrate neurons – an emergent molecular function for AS –, and whether this rewiring underlies novel functions of VN-AS exons in the vertebrate brains.This project will thus deliver fundamental insight into two major unanswered questions: (i) what are the functions of transcriptomic diversification, and (ii) how does transcriptomic diversification impact organismal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Electromagntetic Characterization Of NAnostructured Materials (ECONAM)'.

assistant: **Objectives**

Nanostructured electromagnetic materials are rapidly maturing and become increasingly employed for design of the electronic and optical components, integrated circuits and functional devices. A broad class of applications is based upon the specialised electromagnetic materials that provide the necessary functionality for electronic devices and constitute the physical layer of the technologies dealing with electromagnetic signals. For such applications, the electromagnetic parameters of materials are of the primary concern. Characterisation and metrology of the engineered nanostructured electromagnetic media have become the critical aspects of their development and utilisation in practical applications. The main project objective of this project is to consolidate efforts and bring coordination in the European work towards development, testing, and dissemination of methods and tools for electromagnetic characterisation and metrology of nanostructured composite materials. The main novel characterisation approaches are focused on intrinsically interrelated developments and harmonisation of the material phenomenological models, standardisation of characteristic parameters and measurement techniques for evaluating the specified parameters. The main impact will be in development and dissemination of novel techniques for electromagnetic characterization of nanostructured materials and preparation of standards in the field of nanomaterials characterisation. This will complement the known techniques for characterization in terms of particle and reactivity by developing unified approaches to characterization in terms of permittivity, permeability, chirality parameter, surface impedance, grid impedance and similar.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Innovative in-situ snow parameter sensing system allowing accurate remotely sensed data calibration for improved forecasting of hydro power resources', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

The global goal is improving the energy production from renewable resources. Hydro power facilities fulfil this demand attractively and at the same time help to meet the Kyoto objectives of CO_2 reduction. Efficient energy management of hydro power resources requires accurate forecasting of water capacity from snow melting and run- off. The filling prognoses from snow for hydro power reservoirs is today too inaccurate on the order of 30 to 50 %, as present instruments measure only about half of the snow fall. Because of this the calibration of remotely sensed data e.g. from satellite or aircraft is inaccurate. The prognosis calculations involve snow models which describe the metamorphose, compacting, melting, refreezing, percolation and water saturation, which determine the melting and run-off times.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Euromethodologies x travel assesment' under Fourth Framework.

assistant: **Concept**

The main objective of this project is to develop a common methodology to analyse transport and travel surveys. This is to enable those who design traffic management strategies and policies to get a better understanding of the potential effects on particular socio-economic groups who may lose mobility and access to desired destinations as a result.As travel demand varies across different social groups, regions and time, this project is to investigate the major socio-economic factors affecting behaviour through a comparative analysis of travel demand elasticities in five European countries.An analysis of data available for this purpose is to be performed for several Member States. %
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Molecular architecture of a prototypical trans-synaptic complex: GluD2-Cerebellin1-Neurexin1β', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Chemical synapses in the central nervous system (CNS) employ a multitude of neuronal cell-surface receptors, adhesion proteins, secreted effector molecules, and proteoglycans. Within such vast network of interactions, synapse-spanning protein complexes mediate cell-cell adhesion, align pre- and postsynaptic specializations and exert bidirectional signaling, inducing pre- and postsynaptic differentiation. This proposal focuses on the “Glutamate receptor D2–Cerebellin1–Neurexin1β” trans-synaptic complex, a key component of the excitatory parallel fiber - Purkinje cell (PF-PC) synapse in the cerebellum. This tripartite interaction is essential for bidirectional synaptogenesis, and its specific disruption leads to impairment of cognition and motor coordination. However, the structure of this complex and its implications for synapse organization and modulation of neurotransmission remain unknown.The goal of this proposal is to elucidate the molecular architecture of the GluD2–Cerebellin1–Neurexin1β protein complex, and understand its functional implications. I will use X-ray crystallography to obtain high-resolution structural information on binary and ternary complexes between the soluble, extracellular GluD2, Cerebellin1 and Neurexin1β regions. A range of biophysical methods combined with site-directed mutagenesis will be applied to dissect complex formation with respect to affinity, kinetics, stoichiometry and contribution of functional modules. In parallel, using cryo-electron tomography I aim to visualize and reconstruct the higher-order architecture of GluD2–Cerebellin1, and ultimately the trans-synaptic triad, in model cellular membranes. This integrated approach should reveal general principles of supra-molecular organization and function at neuronal synapses, as str
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Engineering wide band-gap LOW-DImensional systems for advanced perovskite optoelectronics' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Engineering new solutions for powering smart portable devices is key to sustain billion-scale connected objects and to provide a greener alternative to batteries. Indoor Photovoltaics (PVs) - with a projected market of $850 million by 2023 - relying on conversion of visible indoor light- can sustain this challenge, capitalizing on the development of flexible, semi-transparent, colored and easily integrated energy generation devices.Despite the urgency and the large market potential, current PV technologies mostly fail, leveraging on rigid and bulky systems fabricated by energy-intensive processes (i.e. Silicon PVs) or on carbon-based technologies not yet in the market for their insufficient durability. Hybrid perovskites with wide band gap (2eV), with their easy tunability, structural flexibility, and lightweight, hold the potential for a transformative solution in visible PVs. However, lower efficiency compared to low-band gap ones, reliance on toxic elements and insufficient stability hamper their scaling up. ELOW-DI faces this challenge by engineering the perovskite dimensionality as the key variable to unlock device instability while allowing for efficient visible light conversion. This will be obtained i) by developing intrinsically stable low-dimensional perovskites (LDPs) – leveraging on non-toxic elements and stable hydrophobic units and 2) by controlling material nucleation and consequent thin film morphology to obtain vertically oriented crystalline nanopillars, essential to ensure efficient charge extraction in the device while reducing unwanted recombination.Upon the demonstration of the proof of concept on lab-scale, research will be moved to a completely new direction by engineering large area devices while ensuring the scalability of the nanoscale materia
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Competence platform on energy crop and Agroforestry systems for arid and semi-arid ecosystems - Africa'.

assistant: **Objectives**

The objective of this Competence Platform on Energy Crop and Agro-forestry Systems for Arid and Semi-arid Ecosystems is to stimulate bio-energy implementation in arid and semi-arid regions in Africa. COMPETE will establish a platform for policy dialogue and capacity building in the major multi- and bi-lateral funding organisations and key stakeholders throughout the bio-energy provision and supply chains. As global fossil energy resources become constrained, bio-energy is emerging as a major potential resource. The arid and semi-arid regions of Africa and Latin America have, in theory, very large areas of land (and associated water and human resources) available for bio-energy production. However, the production of biomass for energy will result in substantial impacts (pos. and neg.) on ecosystems and cultures of these target regions.  The protection of biodiversity, rural livelihoods and management of scarce water resources are critical considerations in any analysis of the potential for sustainable bio-energy provision in arid and semi-arid regions. Similarly, whilst modern bio-energy could contribute significantly to poverty alleviation in rural areas, the effects of changes to the supplies of natural resources and ownership of those resources must be an integral part of the development options proposed. Therefore, a comprehensive, multi-disciplinary, assessment of current land use, energy demand and technology innovation focused on Africa, will be carried out through COMPETE. COMPETE will link implementation activities, policy development, trade, funding and South-South-EU cooperation. The improved knowledge of national and regional land use and technology options generated will provide the local and international partners with the basis for a complete assessment of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Ultralight and ultrasafe adaptable 3-wheeler' in the context of a Horizon 2020 call.

assistant: **Objectives**

L category vehicles should answer the demands for less energy consumption and affordability and represent an attractive solution in congested cities with scarce parking space. WEEVIL aims to develop a new L category 3-wheeler that is quiet, clean, energy efficient and safe, as well as attractive to the public so that the barriers for adopting it are minimized. The new vehicle concept is an ultralight and ultrasafe adaptable 3-wheeler, with a composite structure using new manufacturing processes for an affordable introduction of these materials in new vehicles. Modularity of elements (including battery packs), system integration and innovative vehicle architecture is considered in the vehicle design. The vehicle has a wheel width varying mechanism in order to allow adaptation to different speeds (wider at high speeds for stability, narrower at low speeds for space optimization and parking). WEEVIL will provide a new electric vehicle concept with innovative design to allow the user to adapt the vehicle to higher speeds or lower speeds and/or parking. Its characteristics will be lightness and safety, with a strong use of composite materials through new and affordable processing methods. A new drive-train with improved energy efficiency will be incorporated, as well as new solutions on system integration such as modular battery packs. WEEVIL solution will break the barriers for extended EV adoption in urban areas, i.e. vehicle capabilities and cost trade-off. A car-like comfort and driving experience in a reduced space (2-3 wheeler vehicle) is pursued. By providing a feasible concept adapted to the users’ expectations, the European EV car pool would be significantly enlarged, providing the pursued benefits on air quality, noise and environmental protection and also bringing