RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Towards the establishment of a permanent European Virtual Institute dedicated to Malaria Research (EVIMalaR).' (EVIMalaR) under Seventh Framework.

assistant: **Objectives**

This is a proposal from 55 partners from 36 institutes to form a NoE that will seek to integrate European malaria research that is directed towards a better understanding of the basic biology of the parasite, its vector and of the biology of the interactions between the parasite and both its mammalian host and vectors. All the member institutes and researchers have demonstrated both their excellence and their ability to contribute to a successful network. The structure of the proposed network significantly evolves prior concepts of network structure introducing new modes of research that have recently emerged. Comprising of 4 research clusters the core activities will include molecular cell biology of the parasite, host immunity, vector biology, population biology and systems biology. One arm of the network activities will be concerned with the timely and effective translation of research respecting the IP rights of partner institutes. The network will also contribute significantly to the production of the next generation of malaria researchers through the operation of an expanded European PhD School for malaria research based at EMBL, students enjoying two supervisors based in different member states. Bespoke training courses for PhD students and network personnel will be offered throughout the duration of the network to maximise individual potential. To create a long term benefit from network activities a limited programme of post-doctoral fellowships within the network will be established. Furthermore, individual career mentoring facilities and an alumni association will continue to guide and engage network graduates. New members will be affiliated annually on a competitive basis with an emphasis on young, emerging Principle Investigators. Through the establishment o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'ENabling SafE Multi-Brand pLatooning for Europe' in the context of a Horizon 2020 call.

assistant: **Objectives**

The main goal of the ENSEMBLE project is to pave the way for the adoption of multi-brand truck platooning in Europe to improve fuel economy, traffic safety and throughput. This will be demonstrated by driving six differently branded trucks in one (or more) platoon(s) under real world traffic conditions across national borders. Following objectives are defined:-Achieve safe platooning for trucks of different brands. Relevant authorities will be approached to jointly define road approval requirements including V2I communication.-Work towards the standardization of different aspects of platooning: manoeuvres for forming and dissolving of platoons, operational conditions, communication protocols, message sets, and safety mechanisms. Platooning Levels will be defined to guide the design of different platooning functionalities and strategies, reflecting the full diversity of trucks with platooning functionality. Stakeholder groups will be set up to ensure that the pre-standards are taken up by the respective organisations and working groups to form the actual standards. If necessary a multi-brand platooning working group will be initiated.-Real-life platooning: The intended practical tests on test tracks and in real life serve a three-fold purpose: 1) “learning by doing” testing across a C-ITS corridor in Europe, 2) assess the impact on traffic, infrastructure and logistics, while gathering relevant data of critical scenarios and 3) promote multi-brand platooning through a final event.ENSEMBLE brings the key actors for deployment together: six major truck OEMs will form the core of the project consortium, supported by CLEPA that will act as an umbrella organisation to involve all relevant suppliers. In addition, a limited number of expert organizations will be involved to cov
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Empowerment and awareness building in river basin management through focus groups and citizens juries'.

assistant: **Innovation**

The project is aimed at bridging the gap between the scientists, decision makers involved in managing European waters, and the public in understanding the challenges of water use and protection. The project will include organization of focus groups in three European river basins - in the Motala Stroem in Sweden, the Emajogi River in Estonia, IJsselmeer basin in Netherlands. Citizens' juries will be organized to test and develop the approach, and to practically increase public participation. Guidelines and policy recommendations for using focus groups and citizen juries in preparation and implementation of river basin management plans will be prepared. Guidelines will be published as training kit, on an interactive website for the distance learning and on CD.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'High-throughput, large area and cost-effective OLED production technologies' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Organic electroluminescence (OLED) holds the promise to deliver flexible, thin, lightweight and power-efficient light sources. Research up until now has been mainly motivated by work on glass-based displays, where the aspects of increased contrast, high viewing angle and response speed are critical. However, intelligent lighting applications are becoming increasingly relevant; here, the unique properties of OLED for high power-efficiency, uniform large-area light emission, and flexibility can give rise to a range of products that can transform the world we live in.<br/>The overall objective of Fast2Light is to develop novel, cost-effective, high-throughput, roll-to-roll, large area deposition processes for fabricating light-emitting polymer-OLED foils for intelligent lighting applications.<br/>The scope of the project comprises all of the layers that are part of an OLED lighting foil. It will start with the substrate choice, and introduce high-throughput deposition and patterning methods for all of the materials necessary to fabricate the final lighting foil. In doing so, it will become clear what device architectures and designs are best suited to integrate these new deposition and patterning methods. The interplay between the choice of device architecture and processing methods will be unravelled and a set of design rules for a manufacturable product will be determined, together with a final process flow. Results will be measurable in the form of demonstrators that prove the performance of the technologies and the design rules.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Management at a distance' (MANDIST).

assistant: **Concept**

Multinationals (MNCs) are key drivers of economic growth, accounting for 33% of global output (OECD 2018). However, within MNCs, the economic performance of foreign affiliates declines markedly with distance from headquarters (HQ). This pattern implies the existence of frictions that restrict how much economic growth foreign direct investment (FDI) can generate in host countries. Understanding the underlying mechanisms has important implications for the economic benefits of FDI and FDI policy. Yet, they remain little understood. In this project, I propose a novel explanation: management problems at a distance. Management problems can be severe even in purely local settings (e.g., Gibbons and Roberts 2013). It is plausible that principal-agent (PA) problems between HQ and the foreign subsidiary manager rise disproportionately when different countries, cultures, languages, and institutions are involved. As previous research has been severely restricted by the scarcity of global organizational data on MNCs, so far, there exists no systematic evidence on PA problems within MNCs and how they can be resolved.I will focus on two solutions: the employment of foreign subsidiary managers that have a certain connection to HQ, and the use of information and communication technology (ICT) to improve monitoring problems. I have been able to identify several novel data sources that can be combined to create the first comprehensive datasets on managers and ICT use within multi-location firms in three historical and contemporaneous settings. Combined with innovative empirical approaches, this allows me to provide the first tests for the existence of PA problems within MNCs and study several channels through which PA problems can affect economic growth: managerial compensation, changes i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'In vitro 3D cell models of healthy and OSTEOpathological ageing bone tissue for implantation and drug testing in a multidisciplinary NETwork' (OSTEONET), addressing dissemination and exploitation.

assistant: **Impact**

OSTEONET aims to (i) build a multidisciplinary research network involving experts of technical and medical disciplines to merge their expertise and exploit possible synergies for the development of reliable and sustainable 3D in vitro cell models of healthy and aged bone tissue and (ii) train a cohort of scientists and technologists in exploiting the model features to increase knowledge on the effects of ageing on bone biology and mechanobiology, and on bone response to drugs, to leverage the use of 3D cell models in clinics and basic/industrial research labs.Bone ageing reduces the quality of life of the elderly and puts social and economic burden on society. Ageing bones fail more easily when challenged mechanically or with toxicants or pollutants, and respond differently to drugs than healthy bone. To personalize therapies and enable better preventive care for the elderly it is essential to develop reliable and sustainable in vitro models of aged bone tissue alternative to animal tests which often fail to capture human-specific features. Several scientific studies support the idea that in vitro models of bone tissue are an outstanding resource for (i) the comprehension of bone physiology, (ii) a better understanding of pathological pathways in most bone dysfunctions, (iii) testing new or repurposed drugs for bone treatment before preclinical trials with animal models.The networking activities planned in OSTEONET will unravel and share knowledge on the mechanisms driving the information transfer from the biochemical and biomechanical levels, which drive osteosynthesis and osseointegration, to the cascade of molecular and cellular events emerging as an elaborated and physiological bone, and on the mechanisms of the different response of healthy and aged bone tissue to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Collaborative Environment for Design of AmI enhanced Product-Services Integrating Highly Personalised Innovative Functions with Minimal Ecological Footprint along Life Cycle and of Their Production P' (PROSECO), addressing dissemination and exploitation.

assistant: **Impact**

The objective is to provide a novel methodology and a comprehensive ICT solution for collaborative design of product-services (Meta Products) and their production processes. The effective extension of products with new services in different sectors (automotive, home appliances, automation equipment etc.) will be achieved by means of Ambient Intelligence (AmI) technology, Lean and Eco-design principles and applying Life Cycle Assessment techniques. New Meta Products, using AmI, will be capable of acquiring knowledge in order to add highly personalized innovative functions, and thus enabling new business models. A Cloud Manufacturing approach will be applied for effective collaborative design of product-services and their production processes, and the effective implementation of innovative services. It will involve all the actors of a value chain, within a product ecosystem, allowing manufacturers to strengthen their competitiveness at the global market. As a result new eco-innovative Meta Products will be offered, which integrate highly personalised innovative functions with minimal environmental footprint along the overall Life Cycle. The Meta Product/process development platform will be provided, including a set of new engineering tools to support collaborative work (simulation, configuration etc.) on new product-services, enhancing existing tools for product/process design.The project will be driven by 4 industrial application scenarios addressing different aspects of service and business building as well as product/process development (complex internal and external supply chains), in order to assure that the means for collaborative service generation and product-service and production process design to be developed in the project will be relevant for industry. The so
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Predicting and monitoring the long-term behavior of CO2 injected in deep geological formations' to be submitted under Seventh Framework.

assistant: **Abstract**

PANACEA aims at developing methods and tools for improved prediction and validation of the long-term behavior of sequestered CO2. The objectives are to: 1) Identify and quantify the factors responsible for the long-term stability of the stored CO2, thus requiring a clear understanding of the dynamics of the injected CO2, chemical interactions with the host rock, and the evolution in time of its partitioning as a free phase (residual or continuous), dissolved or mineralized; 2) Provide measures for the assessment of the integrity and vulnerability of the reservoir (storage formation and cap-rock) and wells that penetrate it, to leakage of the stored CO2, through the cap-rock, faults and or wells;  3) Quantify the impact of the stored CO2 on adjacent subsurface reservoirs, such as changes in the reservoir parameters (pressure increase, pH changes or other chemical reactions) that may lead to unwanted migration of brines, or the release on pollutants trapped in the rock (such as heavy metals), into adjacent freshwater reservoirs; 4) Identify and/or suggest reliable monitoring, measurement and verification (MMV) technologies having the capability to capture relevant information on the long-term behavior of the stored CO2 both at the near and far field; and 5) Achieve an adequate degree of cooperation with other projects in order to allow the collection of data necessary for validating the investigations, including data from large injection sites (Sleipner, Norway), medium size (the future EEPR partially funded Hontomin project, Spain) and small projects (the MUSTANG Heletz, Israel). International cooperation has been arranged with high-profile institutions from the USA, Canada and Australia that have crucial expertise in geological storage of CO2. The combination of extensi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Forward Acquisition of Soil and Terrain for Exploration Rover' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The goal of the FASTER project is to address three key technology developments for planetary exploration: forward looking surface properties characterisation, innovative locomotion system for a scout type rover, and collaborative operation of a mother/scout pair. 1.) The project will develop methods and instrumentation to characterise the properties of planetary surfaces in which robotic rover vehicles operate  to be able to anticipate hazards in advance of locomotion and navigation over that surface. By assessing the soil trafficability for a rover, decisions affecting rover safety (avoiding becoming stuck) can be reliably taken and hazards avoided. 2.) The project will look at what innovation can be applied to ensure that the scout rover is able to operate with minimal risk of encountering hazardous situations from which it must recover. 3.) FASTER will explore the feasibility and performance of a mother/scout rover pair combination and develop methods to achieve successful collaborative and autonomous robot operation. The forward looking scout rover will be equipped with a special combination of sensor technologies to acquire soil and terrain information. This information will allow a risk model to be constructed that indicates the potential hazards that the terrain represents to the following mother rover.  Reducing the locomotion and traverse risks using the proposed advances in autonomous mother / scout collaboration will allow mission operators to explore planetary surfaces with increased safety. It will make possible new levels of autonomous operations by significantly reducing the greatest uncertainty factor – namely properties of the surface material on which the rover must operate. This will lead to increased operational efficiency and, when coupled with the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Promoting inter-european networks of collaborating extended enterprises' in the context of a Fifth Framework call.

assistant: **Objectives**

Many European SMEs within extended enterprises (EE) producing complex products have strong relations/networks with suppliers from countries of the eastern part of Europe. Concerned EEs face enormous challenges during their daily international project work. The all-important factor that will set EEs apart from their competitors is time. Anything that stops the flow of information, materials and money within a project between suppliers, partners, customers and employees will reduce their effectiveness and at the end their market share. The aim of this project is to develop a low-cost and pragmatic information communication technology (ICT) to support EEs. Thereby the objective of PROMINENCE is to give potential support to manage above mentioned challenge by a project managing software tool in connection with e-business application (PRO-MAT), reachable and traceable via internet/intranet by all involved parties within an EE.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Dissecting the role of the ubiquitin proteasome system in the pathogenesis and therapy of B-cell malignancies' to be submitted under Horizon 2020.

assistant: **Abstract**

B-cell malignancies are characterized by high levels of genomic instability, which critically contribute to their pathogenesis and evolution. Recently, the fundamental role of the ubiquitin proteasome system (UPS) in maintaining genome integrity has been appreciated. Two major new therapeutic modalities in B-cell malignancies, proteasome inhibitors and imunomodulatory drugs (IMiDs), target the UPS and demonstrate particular efficacy in multiple myeloma (MM) and mantle cell lymphoma (MCL), two incurable entities with poor prognosis. This suggests the presence of aberrant ubiquitylation events, whose identities have however remained mostly elusive. Our recent studies identify fundamental roles of orphan ubiquitin ligases of the Cullin Ring ligase family (CRLs) and their counterparts, the deubiquitylating enzymes (DUBs) in the cellular DNA damage response machinery, and characterize these candidates as novel oncogenes or tumour suppressors in MM and MCL. These findings provide the foundation for our hypothesis that deregulated ubiquitylation events involving CRLs and DUBs have a far reaching impact on the pathogenesis of B-cell malignancies and can serve as new therapeutic targets and biomarkers. We therefore propose a multistep strategy in which we will (1) characterize previously orphan CRLs and DUBs, which we have distinguished as candidate oncogenes and tumour suppressors in MM (FBXO3, USP24), MCL (FBXO25), or MM and MCL (CRBN), respectively; (2) decipher the global role of CRLs and DUBs in MM and MCL using defined genetic screens; (3) identify relevant substrates of CRLs/DUBs discovered in (2) using mass spectrometry; and (4) validate CRL/DUB candidates in preclinical mouse models and defined patient cohorts as to their disease relevance.We expect that our interdiscip