RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Hydrodynamic Synchronisation in Model and Biological Systems'.

assistant: **Concept**

Cilia and flagella beating in synchronised patterns give rise to metachronal waves, beautiful examples of emergent behaviour in biology. These collective dynamical states are essential in life, transporting nutrients and clearing pathogens; they arise from the mechanical interaction of individual cilia mediated by the viscous fluid.Severe pathologies are associated with cilia malfunction in humans. The current analysis of ciliated tissues in the clinic is focused purely on the frequency of beating: this is insufficient to discriminate between different pathologies. Much more information is present in the cilia dynamics video data that is recorded from patients; it is not being extracted because the correct theoretical framework for analysis is not in place.We will develop our current work on actively driven colloidal systems to selectively test aspects of the biological scenarios, and start a new line of investigation in our lab, with cell culture experiments to validate these findings; we will understand the onset of collective dynamics (new physics), and how cilia waves are robust against fluctuations in cilia beat frequency, spatial arrangement and fluid rheology. New video analysis tools will be developed based on this full understanding of mechanical synchronisation, enabling the collective dynamics to be related back to the behaviour of individual cilia and to the physical properties of the fluid.The team will be of two Post-docs, responsible for the two parts of the project: model and biological systems. A PhD student will contribute to the biological experiments, which present multiple lines of investigation, and will develop the video-analysis code to obtain the full degree of information from biological experiments.The new analysis tool that results from this
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Fatigue Test' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

In reply to the call released by the CleanSky team, named “Fatigue test of sensor integrated CFRP aircraft panels with stiffeners – JTI-CS-2009-2-GRA-01-025”, a consortium has been assembled to perform this project.This consortium encompasses Optimal Structural Solutions Lda (www.optimal.pt) and ISQ – Instituto de Soldadura e Qualidade (www.isq.pt). Acting as as sub-contractor, and to guarantee the specimen will be manufactured to aeronautical standards, OGMA – Industria Aeronautica de Portugal S. A. (www.ogma.pt) will also participate. This team has a wide experience in composite aeronautical structures within their fields of expertise.This project requires 3 core sets of competences, which are covered by each of the involved companies, 1) Engineering of aeronautical composite structures and test campaigns definition and coordination - Optimal Structural Solutions; 2) Testing of composite structures and NDT inspections - ISQ; and 3) Manufacturing composite structures to aeronautical standards - OGMA.These competences have been acquired working in projects for leading aerospace companies. Details on the relevant projects are presented in this document.Together, this consortium is confident it has all the required knowledge and experience to successfully perform the task in hand.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'EXTREME LOADING ANALYSIS OF PETROCHEMICAL PLANTS AND DESIGN OF METAMATERIAL-BASED SHIELDS FOR ENHANCED RESILIENCE' (XP-RESILIENCE).

assistant: **Innovation**

The tremendous impact of natural hazards, such as earthquakes, tsunamis, flooding, etc, which triggered technological accidents, referred to as natural-technological (NaTech) events, was demonstrated by: i) the recent Tohoku earthquake and the following Fukushima disaster in 2011; ii) the UK’s 2015 winter floods which topped £5bn, with thousands of families and businesses that faced financial problems because of inadequate or non-existent insurance. The NaTech problem is quite relevant as up to 10% of industrial accidents, involving the release of Chemical, Biological, Radiological, Nuclear and high-yield Explosives (CBRNE) substances, were triggered by natural hazards. To implement and support the Seveso II Directive 2012/18/EU which regulates the control of major accident hazards involving dangerous substances, XP-RESILIENCE intends to establish a network of individual research projects working towards Advanced Modelling and Protection –via metamaterial-based isolators/layouts- of Complex Engineering Systems for Disaster Reduction and Resilient Communities. In fact, today there is a stronger need than ever to grow researchers that combine a robust academic foundation in reliability/resilience with practical experiences, technological expertise with awareness of the socio-economical context and conviction to furthering research with an entrepreneurial spirit. Hence, the objective of XP-RESILIENCE is to offer innovative research training ground as well as attractive career development and knowledge exchange opportunities for Early Stage Researchers (ESRs) through cross-border and cross-sector mobility for future growth in Europe. XP-RESILIENCE is an inter/multi-disciplinary and intersectoral programme as it includes seven academic partners, one Institute of Applied Scie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Provision of a European Training Infrastructure' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The objective of the EuroTraining proposal is to provide a European Training Infrastructure facilitating the provision of high calibre training across Europe. The structure will support professional advancement training as well as academic training. Professional course providers will get a central place for the presentation of their training offer while academics will get a course material exchange service targeting graduate nanoelectronics schools. The training action will enhance the development of the European knowledge-based society in the field of nanoelectronics. The proposal strongly builds on key building elements from the former EuroTraining project (ICT-211806), however extended with new innovative services, like:- Thematic courses supporting the convergence of advanced More-than-Moore elements with Beyond-CMOS devices- A European platform for multimedia based training- A training material exchange service for graduate schools- A global action offering training support for EU enterprises having operations in Far East- A European wide dissemination of training originating from FP7 projects (IP/NoE/STREPS)- Four new Train-the-Trainers courses for Eastern European universities<br/>All services offered will be gathered in the European Training Infrastructure web site, having 12.000 subscribers and more than 1.2 million annual users.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Self-test2, wine analysis kit for Brettanomyces yeast identification' (2014-2020).

assistant: **Innovation**

The Italian wine market is a cornerstone of the national agri-food sector and is characterized by increasing high-quality wine demand from consumers. Therefore, issues hindering the achievement of wines able to satisfy all market requirements still occur. Brettanomyces spoilage is one of these and it leads to off-flavours and odor formation that highly affect wine quality, causing serious economic losses. The present innovation concerns the setup of a revolutionary device for Brettanomyces self-detection, hereafter referred to as Self-brett®: an easy to use, quick, reliable and cheap new product. Self-brett® enables anyone to carry out self-analysis on Brettanomyces spoilage at any moment of the wine making process, without requiring the involvement of specialized staff, equipments or LAB facilities. Wine-makers, oenologists, oenological product retailers and producers as well as analytical laboratories will embrace Self-brett® because it represents exactly what the wine market is missing now. GRAPE mission is addressed to translate in market services the technical-scientific knowledge acquired by the founders during their academic carriers. Through the development of Self-brett®, already patented, once again GRAPE shows to be innovative and prompt to fulfill customers’ needs, thus offering the first device for wine self-analysis, available at low price, with the potential to reach the entire wine market. Based on an initial investment of 783.180€ (1st and 2nd yr), GRAPE estimates to sell 420K devices by the end of the second year of commercialization (4th yr) and to reach € 4.235.000 of revenues, corresponding at € 1.130.000 net profits and 29,1% ROI, together with a job growth higher than 180%. GRAPE needs to enter the SME Instrument phase 1 to finalize the Self-brett
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Identitying trends in european medical space (contribution of european social and human sciences)' in the context of a Fifth Framework call.

assistant: **Objectives**

- The domain of health and medicine is currently meeting important challenges:1) transformation of biomedical sciences and its impact on care;2) increasing participation of users into medical activities and debates;3) complexification of coordination issues in health organizations;4) multiple articulation of health, social and political questions. On these issues, mixing up social and medical aspects, human and social sciences should add value to public understanding, through analysing and confronting national experiences. ITEMS will synthesize current research and training in human and social sciences, in order to structure a European multi-disciplinary research network, and to prepare the European research area ; to set up the basis for comparing national contexts; to reflect upon the role of human and social sciences as regards policy stakes on health issues, and conceive tools for a large dissemination of research results.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'A Platform for Organisationally Mobile Public Employees' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

The aim of the Pellucid project is to develop a flexible and adaptable platform to assist organisationally mobile employees at middle and higher levels of public sector organisations. Organisational mobility, in which employees move from one department or unit to another, is becoming increasingly common, and brings its own problems and opportunities. The Pellucid platform is a multi-layer, agent-based system to aid these employees in acquiring, reusing and sharing knowledge and experience, benefiting both them and the effectiveness and efficiency of the organisation. The platform will use and integrate technologies such as autonomous cooperating agents; organisational memory; workflow and process modelling; and metadata for accessing document repositories. The platform will be evaluated on pilot sites. It will be customisable to a wide variety of public sector organisations and thus the exploitation prospects are excellent.OBJECTIVESThe overall objective of Pellucid is to develop an adaptable platform for assisting organisationally mobile employees, in effect re-engineering their work in the organisation. This will improve organisation effectiveness and efficiency by formalisation, recording, storage and preservation of experience and knowledge; and supporting workers during integration in a new department or role by giving access to specific knowledge and experience accumulated in the past. At the technical level, the objective is to develop and integrate several advanced technologies in a customisable agent-based architecture. These technologies include autonomous cooperating agents; responsive interaction with the end-users; organisational memory; workflow and process modelling; and metadata for accessing document repositories. The objective is also to obtain experie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Legal feasibility of management of technological risks in the light of the precautionary principle' to be submitted under Sixth Framework.

assistant: **Abstract**

The project is divided in two parts, which are complementary and interactive. The first part of the project (50pc) is focusing on tuition of International environmental law chiefly at Oslo University and supervision of Ph.D. students in Oslo, Bergen and Tromsø Universities in Norway as well as Ph. D. students from other Nordic countries.The second part of the project (50pc) is dealing with a leading edge topic, the compatibility of the implementation of a precautionary principle in order to manage technological risks in accordance with basic legal requirements within International (WTO) law, European Community law and national law (mainly compliance with proportionality principle, free movement of goods principle, non-discrimination principle, principle of coherence, cost-benefit analysis), in particular in the fields of chemicals, waste management and biodiversity.The project involves different universities, different legal disciplines and is of a multi-disciplinary nature.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The Role of Non-Canonical DNA Structures in Insulin Expression' (NC-DNA-INS) targeting Horizon Europe.

assistant: **Abstract**

The insulin-linked polymorphic region (ILPR) resides in the promoter region of the gene coding for insulin (INS). This region consists of a 14-base pair tandem repeat DNA sequence of 5'-ACAGGGGTGTGGGG-3'/3'-TGTCCCCACACCCC-5' and is located 363 base pairs upstream of the transcription start site of insulin. The insulin-linked polymorphic region can form non-canonical DNA secondary structures such as G-quadruplexes, i-motifs and hairpins. Previous work at the UCL School of Pharmacy has shown that different native insulin-linked polymorphic region sequence variants form different DNA structures and these result in differences in insulin gene transcription. This project aims to reveal insights into the relationship between different DNA sequences in the insulin promoter region, the types of non-canonical structures they form, transcription of insulin and how this is influenced by small molecule ligands. The project will use biophysical approaches to determine the structure of different sequences in the insulin promoter, cell and molecular biology to understand the effects of different sequences and structures on insulin expression, including using small molecule ligands as probes. Finally, computational biology and x-ray crystallography will be used to design improved compounds that target the insulin-linked polymorphic region and switch on insulin transcription using structure-based rational design.


**Keywords:** DNA, i-Motif, G-quadruplex, Non-canonical DNA, Gene Expression, Epigenetics, Chemical Biology, Insulin, Diabetes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Scalable & Low-Power Microwave Photonics for Flexible, Terabit Telecom Payloads & High-speed Coherent Inter-satellite Links' (BEACON) targeting Seventh Framework.

assistant: **Abstract**

Telecom satellites are growing like giants employing multiple beams to provide high speed connectivity and broad coverage. Under exploding capacity requirements, vendors admit that a technology and payload architecture switch is mandatory. The new technology has to deliver practical, low-power and scalable components with high performance under harsh environment conditions. BEACON aims to provide this technology and disrupt the transition to multibeam Tb/s satellites. Addressing cost, performance and volume, BEACON invests on the right mix of 3 photonic technologies used in terrestrial telecommunications, i.e. GaAs, Si and doped fibres and combines them to deliver a compact optical beam-forming technology delivering the massive amount of bandwidth. BEACON develops ultra-linear GaAs Mach-Zehnder Modulators (MZM) exhibiting >75dB spurious free dynamic range, 15dB higher than conventional MZMs. MZMs will exhibit: up to 35GHz frequency operation matching Ka-band frequency plans and 1/2 the size of mainstream LiNbO3 MZMs. 6’’ GaAs wafers enable high volume production. BEACON integrates and co-packages 4xMZM arrays with new packaging method. BEACON develops the first scalable multi-core rad-hard erbium doped optical fibre amplifier (EDFA). The EDFA employs new rad-hard doped microstructured fibre and enabling: >50% electrical power consumption reduction than using conventional EDFAs and small form factor packaging. BEACON integrates an innovative photonic beamformer (BFN) using CMOS compatible silicon photonic fabrication together with Ge diodes. The BFN chip consumes <7.5-times less chip area than low-index contrast BFNs. It allows 4 orders of magnitude faster beamsteering. BEACON integrates the system with BFN control and antenna array to demonstrate that the technology can
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Step in a virtual enterprise' (SAVE).

assistant: **Innovation**

Objectives and content The SAVE project aims to enhance the competitiveness of European Industry through the use of standards in support of the Engineering Supply Chain. It will show how data and information can be delivered to the right place at the right time in the right format and with the right CAD-CAM tools and applications being made available at lower cost for SME members of the supply chain. A working prototype will be delivered that will show how a supplier can gain remote access to the lead contractor CAD- CAM/Product Data Model/Enterprise Resource Planning systems to pull the latest data and information relating to a particular task he has been asked to carry out. The technical objectives of the project are: To develop a Virtual Enterprise Data Model - This will take and extend existing information modelling standards (STEP AP 203,AP214, AP232) to create a central model which represents the different contractual relationships and business protocols which govern engineering information exchange in a Virtual Enterprise. To develop tools to support a mapping methodology which will allow members of a Virtual Enterprise to translate their own, proprietary models and ways of working into the Virtual Enterprise Data Model. To implement a Virtual Enterprise Framework based on standards (CORBA, AIT Reference Model, AIT Implementation Platform) which will enable companies at whatever level from prime contractors to 2nd tier suppliers (and beyond), to, at low cost, rapidly join, participate in, and leave a Virtual Enterprise, exchanging and sharing information and applications with high degrees of integrity. The use of Java Applications and remote access to high cost tools through Intranet/Internet technology will be a key element of reaching this goal. Expected benefi