RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Federated Learning-based Distributed Control for Heterogeneous Platoons of Connected Autonomous Electric Vehicles' (FEASIBLE), addressing dissemination and exploitation.

assistant: **Impact**

To promote the EU's sustainable development of environment and economy, EU planned to reduce emissions from conventional vehicles in European Green Deal. Heterogeneous platoons of connected autonomous electric vehicles (HPCAEVs) are thought to be the most efficient, viable, and promising solution to reduce both energy consumption and pollutant emissions produced by conventional vehicles and improve road efficiency. However, since HPCAEVs are still in the evolving stage, the secure and energy-saving operation of HPCAEVs in mixed traffic flow is suffering significant challenges. The FEASIBLE project is proposed in the context of addressing these challenges by providing some scientific foundations that enable the secure and energy-saving operation of HPCAEVs in mixed traffic flow, with particular focus on networked modeling, stability analysis, and control design. First, network-level federated learning (FL) models will be set up by incorporating intrinsic characteristics of HPCAEVs, macroscopic traffic flow, surrounding vehicle flow, and their interactions. Second, novel stability analysis criteria for HPCAEVs will be derived with expected dynamic performance by designing a FL-based Lyapunov function with sufficiently small and bounded modeling error. Third, FL-based distributed robust model predictive control methods for HPCAEVs with intervehicle distance constraints will be developed under surrounding road conditions. Finally, advanced simulations and tests of HPCAEVs will be conducted to demonstrate the effectiveness and practicality of the proposed modeling and control methods, and the control performance will be compared with cutting-edge methods.


**Keywords:** Autonomous vehicle platoons; distributed control; secure operation; emission reduction; energy conservati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Mineral Scale formation: from the atomic to the field scale' in the context of a Seventh Framework call.

assistant: **Objectives**

The MINSC Initial Training Network (ITN) is comprised of partners from first-rate universities and high-level industrial partners located in the United Kingdom, France, Denmark, Iceland, Germany, Norway, and Italy. The prime aims of this network is to provide research and training opportunities to a new generation of young fellows in fundamental and collaborative research projects related to the nucleation and growth of a series of relevant scale mineral systems in the absence or presence of inhibitors agents. The training will combine molecular level research with studies linked to clear industrial processes at the field-level. The ultimate goal is to betterunderstand one of the highly relevant problems in oil, geothermal and food industrial processes: pipe clogging and surface corrosion by mineral scale precipitates during production. To achieve this, the network will combine training of early stage and experienced researchers in state-of-the-art techniques of mineral formation and characterization both in laboratory and industrial settings with research objectives that aim at quantifying the nucleation and growth of several mineral systems: carbonates, sulphates/sulphides, oxalates and silicates. Scaling can often be retarded via inhibitors but their role in affecting rates of formation of these minerals in solution, on surfaces as well as in real-world industrial settings (i.e., pipes, cores etc.) are unknown. We will determine these rates in laboratory experiments and implement and test these novelfindings directly in industrial power plant systems. The prime industrially-driven science goal is twofold (a) to better understand what leads to the precipitation of a series of mineral scales causing a massive decrease in efficiency and increased cost for industrial pro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'His-Li mouse, the unique humanized mouse model resembling human liver and immune systems' to be submitted under Horizon 2020.

assistant: **Abstract**

Preclinical toxicology evaluation is the most critical step in pharmaceutical drug development, representing about 21.2% of the total drug development costs. About 70% of drug development programs fail due to toxicity or unexpected issues in Absorption, Distribution, Metabolism, and Excretion (ADME) at Phase 1 validation on humans. The main problem lies on the lack of accurate and reliable pre-clinical mouse models: in fact, current models fail to reflect human liver physiology, and often lead to the development of drugs that are safe in mice, and reveal unpredictably toxic or even deadly in humans. Strikingly, only 13.8% of drugs development programs are finally approved. The development of a single drug requires at least 1,000 iterations, accounting for about €10 M in total, and procedures that can take up to 10 years.TransCure bioServices offers the His-Li-mouse, a humanized mouse model for pre-clinical drug testing, based on the unique combination of the humanized liver and immune systems. His-Li-mouse is the first pre-clinical model that perfectly reflects the human liver physiology and immune response, thus representing a unique tool to perform reliable pre-clinical safety and efficacy tests of drugs. His-Li-mouse enables to reduce the failure rate observed when reaching the clinical trials and to subsequently eliminate unnecessary and costly experimental iterations. This will benefit to the global population, as a more efficient drug development process will potentially save millions of lives or improve its quality by enabling the faster discovery of breakthrough pharmaceuticals.During the phase 1 feasibility study, TransCure will establish a sound go-to-market strategy and supply chain, and will draft further development plans. During the innovation project, Tra
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The role of axonal cell adhesion molecules in optic nerve regeneration' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

To compare TAG-1 expression after optic nerve injury in fish and rodents. To ablate TAG-1 function in fish retinal ganglion cells (RGCs) using antibody and inhibitory protein reagents. To introduce TAG-1 function into regenerating rodent RGCs using transgenic techniques, hormonal induction and injection of purified protein. Use reporter gene constructs in transgenic mice and fish to identify key regulatory elements involved in TAG-1 and F3 expression in RGCs before and after injury. Use sequence analysis, in vitro footprinting techniques and site-directed mutagenesis to identify transcription factor binding sites within the relevant regulatory elements. Use comparisons between fish and rodents to investigate the expression of F3 and other potential candidate axCAMS. The peripheral nervous system (PNS) of mammals, and the central nervous system (CNS) of some lower" vertebrate species, are capable of regeneration. In contrast, the CNS of mammals shows particularly poor regenerative capacity. We will look after CNS injury, in rodents and fish, at the expression of a set of axonal cell adhesion molecules (axCAMs) known to be expressed during embryonic axonogenesis. Regeneration after injury may depend on the ability of the injured neuron to re-express specific embryonic axCAMs. We will exploit the different regenerative capacities of fish versus rodents to identify axCAMs differentially expressed in these species during regeneration. Such molecules are likely to play a role in whether or not axons will regenerate. The major goal of this proposal is to understand the regulation of such axCAMs in response to axon injury, with the objective of manipulating their expression to test whether they contribute to regenerative capacity.  Recent results reveal a marked lack of re-expr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Biodegradable solutions for packaging of liquid dairy products'.

assistant: **Innovation**

This research proposal intends to develop innovative plastic bottles and bags manufactured in biodegradable materials that fulfil the requirements for packaging of different types of dairy products.One of the main drawbacks for the wide application of biodegradable materials currently available on the market in certain applications is their thermal resistance, in comparison with traditional plastics such as high density polyethylene, HDPE or polyethylene terephtalate, PET. Biodegradable materials show a limited range of temperatures of use, up to 50-60ºC depending on their composition.Plastic bottles and bags intended for packaging of dairy products are subjected to medium-high temperature during sterilization and transportation, and therefore thermal stability of the material is a major drawback of biodegradable resins to be introduced into this wide market.To overcome these limitations the use of reactive extrusion is proposed. The process essentially forms chemical bonds between the polymer chains resulting in a dense network of very high molecular weight. This polymer becomes less mobile when subjected to heat or mechanical loads, and with this, properties such as heat distortion, ESCR, creep and abrasion resistance are enhanced.The main challenge in this project will be modifying the chemical structure of the biodegradable materials to increase thermal resistance without decreasing their mechanical resistance and their biodegradability properties for plastic bottles and pouches for the packaging of different types of dairy products.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Improving patient outcomes and reducing cognitive load of clinical staff in intensive care through medical-device interoperability and an open and secure IT ecosystem' in the context of a Horizon Europe call.

assistant: **Objectives**

Over the decades, technical developments have resulted in a variety of different medical devices that dominate today's intensive care work environment. Beside all the clinical capabilities and benefits these technologies provide, devices also contribute to an increasing complexity in care. Using technology stresses the cognitive strain put on healthcare providers in critical care. Combined with a big lack of clinical staff the complexity leads to an enormous workload.To tackle these challenges the consortium consisting of four Universities and their clinics and four industrial partners plans to demonstrate the benefits in clinical outcomes and workflow efficiency through standardized, bi-directional interoperability of medical devices based on the new standard ISO/IEEE11073 SDC. During the project SDC solutions will be provided for different use-cases to reduce the quantity of alarms around the patient bed and securely distribute them to the responsible caregiver, allowing to keep the alarms silent at the bedside. Furthermore, algorithms shall be provided to analyse the root cause and urgency of an alarm. The latter is supposed to support in decision making whether immediate action is necessary. The IT infrastructure and algorithms will be evaluated in four different clinics. In addition, AI-based pattern recognition will used for early detection of patient deterioration in order to prevent negative long-term outcomes and prolonged ICU stay.Key deliverable will be a Targeted Alarm System (TAS) including several IT tools on the industrial side and study reports on the effectiveness of the TAS from the clinical partners. Realising this, a standardised IT-solution for monitoring ICU patients should be the next step after the project. On the long run it is intended to reduc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'A Coordinated and Structured International Post-Doctoral Program to Foster Trans-national Mobility and Independent Career of Scientists in Biomedicine'.

assistant: **Concept**

This program encompasses the coordinated action of three major Biomedicine Research Centers and a Biotech shell in Lombardy, to launch a new Structured International Post-Doctoral program (SIPOD). These research centers operate in conjunction with the Scuola Europea di Medicina Molecolare (SEMM) whose aim is to promote the training and research of young scientists within emerging sectors of biomedicine. SIPOD is designed to attract excellent scientists and to boost their career as post-doctoral fellows towards becoming successful and independent group leaders. SIPOD aims to foster the incoming trans-national mobility and the reintegration of fellows.  SIPOD is characterized by: 1. Trans-national mobility and re-integration of fellows. 2. Freedom of choice for the fellows to select the research topic and destination within the receiving Host Institutions. 3. Equal Opportunities for men and women, and consideration of career breaks. 4. Higher education program based on five training activities: Patenting, Tech transfer and Licensing; Grants scouting, writing and management; Team leading and Group organization; Translational Research and Clinical Trials; Ethical issues in science.  5. Fostering the career development toward successful and independent group leaders. This program stems from internal and external post-doctoral surveys indicating that at present the career transition from postdoctoral fellow to group leader (independent investigator) is not supported by an adequate training/educational support. SIPOD is designed to fill this gap.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Power consumption and CO2 footprint reduction in mobile networks by advanced automated network management approaches' (GreenNets), addressing dissemination and exploitation.

assistant: **Impact**

ICT energy consumption is a growing concern. With an expected exponential growth in data transport, the communications infrastructure alone may soon become one of the largest energy consumers in the world. This trend has long been detected and is addressed at various levels. The first to respond were the equipment manufactures, and modern equipment is considerably more energy efficient than the one deployed a decade ago. Given the growth rates in mobile data traffic, better equipment alone will not suffice to successfully fight exploding energy demand. Its smarter use, exploiting inherent, yet not fully explored intelligence in the networks shall further improve energy efficiency.The objective of the GreenNets proposal is to tackle this challenge for cellular radio networks. This is to be done by developing sophisticated methods and tools in four directions: for analyzing the energy efficiency in existing deployments; for finding measures to improve the efficiency; for implementing those measures in dedicated software platforms; and for establishing the ability to migrate to more energy efficient radio network deployments in face of sharply rising mobile network traffic. The ambitious aims of the project call for R&D activities that will extend and complement the platforms, tools and methodologies already in the possession of the participating SMEs. In a nutshell, the research aims at establishing two complementing functionalities: First, an automated network management that continuously adapts network activity to match the spatial and temporal network traffic variations. This shall leverage better efficiency in the short-to-mid term. Second, the ability to optimize the evolution of network deployments such that they become even more energy efficient in the mid-to-long
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'GENIE:  GeoEngineering and NegatIve Emissions pathways in Europe'.

assistant: **Objectives**

Geoengineering technologies, such as solar radiation management (SRM), and negative emissions technologies, such as greenhouse gas removal (GGR), are emerging options to address climate change. This project will investigate the environmental, technical, social, legal, and policy dimensions of GGR and SRM. We provide an urgently needed interdisciplinary and holistic perspective of these technologies in order to understand conditions under which they might be deployed at scale. Our meta-analytical framework integrates insights from social science, engineering and physical science disciplines to provide a comprehensive view of GGR and SRM in the transition to climate neutrality in Europe and the world. The project will conduct excellent research and generate a robust, scientific assessment for evidence-based policymaking. Our research framework consists of three pillars—techno-economic systems, socio-technical systems, and systems of political action—within which we place six work packages (WPs). These are: (1) Understanding the current state and future potential of GGR and SRM technologies in terms of their technical and economic features; (2) Analysing bottlenecks in transitions to climate neutrality and their implications for deployment; (3) Identifying social acceptance and legitimacy constraints, (4) Learning, diffusion, and adoption; (5) Implications for Sustainable Development Goals of archetypical mitigation pathways; and 6) Policy options and governance. A crosscutting WP7 synthesizes research along three salient, but under-researched themes: A) Socio-technical change; B) Managing transition risks; and C) Political economy and feasibility of deployment. WP8 focuses on stakeholder engagement, entailing scenario co-design, science-policy dialogue formats, and specif
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Network Analysis in Neocortex during Passive and Active Learning' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

How does the brain perform the complicated computations that allow us to learn about and interact with the environment? The rapid advances in new optical imaging, the powerful statistical analysis/machine-learning techniques, and the availability of computational resources, provide a unique opportunity to decipher this fundamental question. NeuronsXnets forms an international, multidisciplinary and intersectoral collaboration network involving leading groups in neuroscience, neuromorphic computing, data science, systems, optical tools/imaging, and hospitals.  It takes advantage of this unique environment to improve the understanding of neural circuit function and integrate its findings in deep learning architectures and in neuromorphic circuits, aiming to develop a new generation of computing technologies based on the organizing principles of the biological nervous system, optimized for higher levels of cognition. NeuronsXnets will perform knowledge transfer through hands-on training and research activities during 196 secondments, courses, 4 international workshops, and seminars, to train a new generation of highly skilled systems neuroscientists and computer scientists/engineers. All partners, especially the SMEs, will benefit from the cross-fertilization, by integrating the findings and systems they have developed in their existing solutions or in new systems, capitalizing on the research results that will be achieved, and creating a long-term link between business, research, higher education & hospitals. Through open access to the developed tools and collected data, NeuronsXnets can make significant impact on the scientific community. We are committed to educate and mentor young students and raise the public knowledge about the fascinating field of neuroscience. We w