RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Decomposition and Discovery of Complex Networks'.

assistant: **Objectives**

In complex systems, individual components interact with each other often in non-linear ways via a non-trivial network of interactions.The structure of such network of interactions affects that system's dynamics and conveys information about the functional needs of thesystem, its evolution, and the role of individual units. For these reasons, network analysis has become a cornerstone of fields as diverse as systems biology, economics and sociology.In these fields, the advance of technology has boosted our capacity to gather increasing amounts of data on large complex systems. Unfortunately, our understanding has not grown proportionally. Two of the main reasons for such disparity are: (i) that we lack a complete set of tools to summarize information and transform it into practical knowledge; (ii) he reliability of network data is often a source of concern and poses serious questions about the validity of the conclusions of network studies.The proposed research addresses these the two issues outlined above based on two premises: (i) that group-based models, or more generally block models, are good descriptors of patterns of interactions between nodes in a network, and (ii) that every observed pattern of interactions is the result of the overlay of several block models.The overarching goal of the proposal is to develop a framework that enables the identification of a set of orthogonal block models, and the discovery of complex networks from sparse/incomplete empirical data sets; and to apply this framework to problems in systems biology.The research I propose is innovative in its ideas and will shed light on the mechanisms that shape network structure. Importantly, because the methodology I will develop is based solely on the topology and  is independent of network context
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Elasticity, capillarity and imbibition in textiles'.

assistant: **Concept**

Fibrous media are ubiquitous in natural and engineered systems, due to their versatility, flexibility and functionality. Nonwovens (i.e. entangled fibrous networks), and especially natural fibre -based materials such as paper or flax mats, are heavily used for a variety of applications, and could be largely developed as a sustainable alternative for plastics. The first limitation of their widespread use is their response to humidity, wetting or drying, which is unavoidable in many applications, and is a key step of their manufacturing processes. The ElCapiTex project aims at characterizing and modelling the specific behaviour and properties of wet non-woven textiles (consolidation, imbibition, mechanical response, deformation) and of their manufacturing processes. In order to characterize the complex interplay between the various physical mechanisms that gives rise to the global properties of textiles (hydrodynamics, capillarity, elasticity, swelling), we will combine different approaches coming from three recent active research areas of fluid-structure interactions: the transport of suspensions of elastic objects, elastocapillarity (i.e. the deformation induced by the capillary forces associated with liquid-air interfaces), and poroelasticity. We will work with a hierarchy of experimental model systems of increasing complexity, in particular by fabricating model nonwoven sheets from gel fibre suspensions. We will further build theoretical models, based on recent statistical approaches used to describe the mechanical properties of dry textiles. Understanding these physical mechanisms is mandatory to develop innovative processes and materials; reconciling fundamental pore-scale mechanisms with network behaviour will allow for the design of tailored fibrous media with spe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Urban vibrations: How physical waves come to matter in contemporary urbanism' (WAVEMATTERS).

assistant: **Innovation**

Cities are critical zones where the intermingling of environmental processes, infrastructural arrangements and human lives is increasingly apparent and disputed. Physical waves, particularly heat radiation, sound waves and radio frequencies, constitute major environmental disturbances that invisibly cross the urban built environment affecting bodies, human and nonhuman, in harmful and uncertain ways. By asking how they come to matter, this project explores how waves become associated to specific bodies and environments, as well as how they become matters of public concern and design intervention. To answer these questions, this project entails extended ethnographic fieldwork at key locations where ur-ban projects aimed at mitigating the urban heat island effect, abating environmental noise and building 5th generation wireless communication networks are currently unfolding. Following techno-scientific researchers, city officials, professional consultants, affected groups and concerned residents, the project will address two major research problems: 1. How bodily exposure is done in practice, paying attention to both knowledge production and controversies concerning wave-related exposure, as well as to how individuals learn to be affected by and bodily attune to physical waves. 2. How waves problematize forms of urban coexistence leading to design interventions that reassemble (and disassemble) urban environments, as well as to practices of imagining other possible urban environments. A unique feature of this project is its emphasis on expanding conventional ethnographic research by means of multimodal collaborations with actors from the field, thus actively engaging in multimedia forms of knowledge pro-duction, prototyping or community building. This is indeed crucial to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Pulsehaler™ - A Breakthrough Treatment  for COPD' (OPEN-LUNGS).

assistant: **Concept**

Chronic Obstructive Pulmonary Disease (COPD) is a progressive, debilitating, disease of the lungs which affects 50M Europeans and kills 160,000 every year, with an annual cost burden of €141B.  Respinova Ltd. has developed a novel device, called Pulsehaler™, to treat COPD in a revolutionary way by re-opening the small airways which are known to collapse in COPD patients thereby making it increasingly difficult to breathe. No other COPD treatment in the market today can effectively open these airways. In a clinical trial, PulseHaler™ was shown to substantially improve exercise capacity (the strongest predictor of morbidity and mortality), breathing ability, and quality of life of COPD sufferers. If Pulsehaler™ can reduce costs by the same magnitude to which it has been demonstrated to improve patients’ exercise capacity, the current cost burden of COPD in Europe could be reduced by up to €21B annually.We intend to complete several actions in this project which will bring Pulsehaler™ to the commercial market, and allow Respinova to scale up into a world leader in treating respiratory diseases. A multicenter international clinical trial will be conducted to further build data on Pulsehaler efficacy and support marketing launch. We will obtain CE Mark regulatory approval, and proceed to launch the Pulsehaler™ in the market, scaling up sales, marketing, and production.  Respinova Ltd. is a SME based in Israel with 12 employees currently. We have a seasoned management team with decades of combined medical device, business and leadership experience. We are a Horizon 2020 SME Phase II SME grant winner, and two-time EIC Seal of Excellence winner, for our Pulsehaler™ technology.


**Keywords:** Chronic Obstructive Pulmonary Disease, Coronavirus, COVID-19, respiratory disease, lun
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Induced pluripotent stem cell seeded active osteochondral nanofibrous scaffolds' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

iP-OSTEO project focuses on development of novel cell-based scaffolds for bone and cartilage repair in patients with poor regenerative capacity. We are proposing technology combining iPSCs with improved regeneration capacity combined with nanostructured scaffolds based on electrospun scaffolds and drug delivery system stimulating cell regeneration based on electrosprayed and spray-dried particles. The system will deliver novel treatment method for older patients, for which the current cellular and cell-free methods are ineffective. iP-OSTEO will reach its goals by creating an international and interdisciplinary training program. 7 companies (SMEs) and 7 academic institutions across European Union will join there forces though dedicated secondments. The activities will involve networking, research/training, workshop and dissemination secondments. The project has in total 239 secondments involving exchange of Early-stage and Experienced researchers. The consortium is bonded by Dr. Eva Filova – young scientist with experience in bone and cartilage tissue engineering. The iP-OSTEO project will help in better integration of academic and industrial stakeholders across Europe and help diseased people by providing novel therapeutic methods. Nevertheless, project has 169 ESR secondment months leading to training of new generation of scientists with international connection and knowledge of intrasectorial enviroment.


**Keywords:** iPSCs, scaffolding system, osteoporosis, osteoarthritis, ageing, musculoskeletal disease, 3D cell culture, bioreactors, personalized medicine, drug delivery, controlled release, nanofibers
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Using real-world big data from eHealth, biobanks and national registries, integrated with clinical trial data to improve outcome of severe mental disorders' (REALMENT) under Horizon 2020.

assistant: **Objectives**

Mental disorders represent one of the largest burdens for the European Health Care system, due to large number of patients and a lack of efficient treatment options. Today, drug treatment of mental disorders is characterized by severe adverse effects and suboptimal response in more than a third of the patients. Optimizing treatment is based on a trial-and-error approach, which combined with frequent multi-morbidities, often leads to polypharmacy and poor outcome. Due to limited understanding of the disease mechanisms that underlie mental disorders, new drugs with novel therapeutic targets are lacking, and existing treatments are ineffective for many people. It is therefore urgent that cutting-edge research approaches are deployed to develop innovative tools to individualize treatments using available psychiatric medication, and thus improve clinical outcomes and reduce costs for health care systems. The main goal of the multidisciplinary REALMENT project is to optimize treatment of mental disorders through novel precision medicine strategies based on current pharmaceutical options. REALMENT includes world leading research institutes and pharmaceutical industry at the very forefront of mental disorder research. REALMENT will achieve its objectives by exploiting population-scale Real-World Data (RWD) in combination with Randomized Clinical Trial (RCT) data available to the partners. Big data from populations (Nordic registries), cohorts (European biobanks), and eHealth samples (medical records), including whole genome genotypes (n=1.9 million), will be analysed in an EU-wide sustainable infrastructure using artificial intelligence and machine learning to develop prediction and stratification tools (precision psychiatry). These algorithms will be validated in large RCT dat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Interoperable Platform Relying On VocaliD Engineering and Deployment' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

i-Proved promotes early exploitation and adoption of VocaliD, a new smart card technology provided with an embedded acoustic interface able to emit encrypted authentication codes. i-Proved establishes and evaluates secure transactional platform with value-added on-line (telephone and Internet) and in stores services in a European context. The VocaliD new generation smart card meets e-commerce security and mobility requirements, and EMV international standard for in-store payment compliance. The e-security model is based on the use of pseudo-random (or encrypted) sound sequences, emitted by the smart card, transmitted online through any telephone set or computer's microphone, with no additional reader required.i-Proved has a three phase approach:(1) conception and establishment of the multi-application transactional platform,(2) production, personalisation and distribution of the card packages, and(3) validation and promotion of the results.Objectives:i-PROVED aims at validating and demonstrating the use and utility of the VocaliD technology in a real world environment;i-PROVED detailed objectives are:- Set up a pan-European VocaliD transactional platform (payment / access control), as a technical reference for integrators and services providers, who want to test and adopt the solution;- Demonstrate VocaliD benefits such as immediate mobility and interoperability of the solution thanks to multiple service access possibilities;- Demonstrate the multi-application potential of a VocaliD based platform, by allowing value-added service providers to easily plug to the platform, personalise and upgrade their services, in a secure online environment;- Demonstrate global convergence online / in-store between: magnetic stripe available and adaptation of a bi-chip module (acoustic/
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Replacing chemical fungicides with innovative, cost-effective plant-based solutions, to cut food waste and carbon emissions and enhance food security' in the context of a Horizon 2020 call.

assistant: **Objectives**

Globally, over 45% of fruit and vegetables  are lost in the supply chain each year. The economic and environmental cost of this avoidable food loss is high. Producers, distributors and retailers report annual losses of €30 bn because of food waste caused by moulds, a subset of fungi, and this food waste ends up in landfill where it generates greenhouse gases. Conventional control of fungal infestation relies on synthetic fungicides, linked to declines in insect populations and increasingly subject to restrictions. There is an unmet need for efficient, natural alternatives. AgroSustain has identified and patented over 60 antifungal plant-derived compounds, to develop a portfolio of highly efficient, cost-effective, natural fungicides. In this project, we will commercialize our product, AgroStore, which has unprecedented fungitoxic efficacy against a broad spectrum of moulds. Our solution provides similar crop protection in the pre-harvest phase to the currently available synthetic fungicides and extends the shelf life of fresh produce post-harvest, by a minimum of 7 days and up to 4 months. This will allow food producers, retailers and distributors using AgroStore to greatly reduce their food loss costs and improve food quality for consumers. By reducing food waste, AgroSustain also cuts the associated carbon emissions in landfill.  Studies have demonstrated that our product has no adverse effects on insect life, soil or water.Following the successful outcome of our Phase 1 H2020 project, this EIC Accelerator project aims to complete the development of the marketable version of AgroStore, secure toxicity certifications, regulatory approval and product registration. We will conduct extensive pilot trials with producers, large retailers, distributors and branded fruit comp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Clean and efficient microCHCP by micro turbine based hybrid systems' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Fit4Micro aims to develop a hybrid microCHP unit running on sustainable liquid biofuels. Application is foreseen at multi-family houses, and more specifically at remote and/or off-grid locations. The innovative system is based on a double shaft micro gas turbine (mGT) combined with a novel humidification unit. This unique combination leads to very high electrical efficiencies (>40%) as well as a very flexible heat:power ratio. Low emissions are achieved by the application of flameless combustion, and a high GHG emission reduction is obtained by using truly advanced, RED2 compliant biofuel.Use of a mGT as core-unit in Fit4Micro is ideal for domestic usage, as the system has very low noise output and is vibration free. Furthermore, rapid response times and fuel-flexible operation make this the ideal base for a highly efficient hybrid CHP system, resilient to changes in (local) fuel and power markets, empowering the consumers through digital solutions. Furthermore, the Fit4Micro unit will be integrated with a compression heat pump, an innovative adsorption and a solar PV system through the DC power system avoiding transmission losses. A smart control system will be developed to enable optimal performance at all times. Efficient fuel distribution and off-grid operation of Fit4Micro is enabled by using sustainable liquid biofuels. These fuels will be produced from biomass residues and organic waste streams, through fast pyrolysis followed by mild hydro-processing yielding a hydrotreated pyrolysis oil (HPO). In Fit4Micro the objective is to widen the feedstock basis and lower the fuel costs by i) using residues as the primary feedstock, and ii) by limiting hydrogen consumption by application of mild processing conditions.Besides technological development work, the Fit4Micro p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'ImmunoPET directed to specific subtypes of GABAA receptors as strategy for molecular mapping of behaviour and mental illness' (GABARPET) under Horizon 2020.

assistant: **Objectives**

Changes in GABA receptors are known hallmarks for numerous neurological diseases including schizophrenia which is a severe psychiatric disorder that has a profound effect on both the individuals affected and society. The diagnosis of schizophrenia is complex because of the loss of high specific biomarkers. Research papers have suggested that the differential expression of GABAA receptors in the brain is associated with this mental disease. The current evidence on GABAergic abnormalities in schizophrenia is mostly based on postmortem studies and, in this sense, in vivo measurements of GABAA receptor subunits can reveal additional insights. This project will develop Positron Emission Tomography (PET) probes which could unveil quantitative information about GABAA receptor expression in schizophrenia patients. However, the lack of imaging tracers with high affinity and specificity do not shed a clear light on the diagnosis in a traditional PET setting. In this sense, the immune-positron emission tomography (immunoPET) is a non-invasive technology based in antibody imaging which reveals a specific and sensitive molecular characterization of the cell surface phenotype in vivo. Nevertheless, its success in neuroimage is limited because of intact antibodies cannot penetrate the Brain Blood Barrier (BBB) in healthy conditions. However, GABARPET will tap into a small recombinant bispecific antibody construct targeting the GABAA receptors as well as the transferrin receptor because it is able to readily transmigrate across the BBB in vivo after peripheral injection.This project wants to develop di-single-chain variable fragment (di-scFv) directed to α1 and α2 subunits of GABAA receptors. Then, they will be labeled with conventional radionuclides produced by cyclotron as 18F and 89