RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Poverty, Child Protection and Parents' Participation' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The proposed project aims to promote innovative, poverty-aware forms of parents' participation and family inclusion practices in child protection policy and practice. More specifically, it intends to strengthen the connection between three bodies of knowledge—poverty, child protection, and parent participation. Parent advocacy programmes, that are gradually developed to support family inclusion and parents' participation at the practice and policy levels, are demonstrating positive outcomes, both in terms of proximal and distal outcomes. Even though, current programmes are mainly based outside of Europe and tend to lack a firm theoretical and ethical base that informs practice in ways that address poverty, other social inequalities, and child protection practice. Given the increasing numbers of children living in socio-economic hardship in more than two thirds of the OECD countries, alongside rising numbers of children involved in the child protection and court systems in various EU countries, developing such practices is a necessity for promoting the well-being and rights of children and Therefore the study aims are:(1) To map, describe, and conceptualize the development and application of parent advocacy programmes in England. (2) To explore the experiences and perspectives of all stakeholders who participate in parent advocacy programmes (3) To examine and theorize the relevance of poverty-aware approaches to parent advocacy programmes. (4) To empirically enrich and further develop the complex relationship between poverty and maltreatment. The research project will employ a qualitative in-depth case study approach that will involve a preliminary survey of all existing advocacy initiatives in England and in-depth inquiry of 4-6 parent advocacy programs. The case studi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Design and prototype production of a windturbine rotorblade for the 46-50 m diameter class' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

Project objectives The project concerns the design, prototype production, laboratory testing and field testing of a windturbine rotor in the 46-50 m diameter range or even bigger. The special design features are a low weight blade, reduced tower trust and minimized noise emission. A test blade will be built to be laboratory tested, static as well as in fatigue at RISØ. A test set will be built to do a field test on a commercial Nordtank windturbine. During the field test loads, noise and power will be measured. Technical approach A new Delft University DU95-W-180 cross section will be chosen together with the well known DU25 sections. These cross sections combine a desired thick cross section with aerodynamic desirable properties such as high lift to drag ratio and reduced sensitivity for nose roughness. The special airfoil was designed and windtunnel tested for lift over drag ratios of at least 130 at the design Reynolds number of 3.0 * 106. To reduce peak loads the maximum lift coefficient is around 1.25. With the ECN computer code Bladeopt, the blade geometry will be generated. This code optimizes the blade geometry for maximum annual yield and lowest tower trust. With the FOCUS computer codes the structural blade design will be made. The structure and materials will be based on the standard Rotorline production method with fibre-glass polyester. One blade will be built for laboratory strength testing at RISØ. Successively a field test on a turbine will be performed to measure the power curve, loads and noise emission. Expected achievement and exploitation The blade should have an annual output of a least 1250 Wh/m2 aerodynamically in a wind class II climate. For a 50 m diameter rotor this gives an aerodynamic annual yield of 2.45 Gwh. The structural rotorblade weigh
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Microscopically designed environments for cold atoms' under Seventh Framework.

assistant: **Concept**

The field of ultracold atom research has grown into a mature area of physics very quickly after its initial successes of laser cooling and the seminal achievement of Bose-Einstein condensation in dilute atomic vapors only a few years later. Today, the state of the art in the field is such that applications in a numerous directions are being pursued and/or within reach in many domains. On the one hand, very general questions in physics can be addressed, such as controlled preparation and studies of dynamics of single or few particle quantum systems. On the other hand, technological applications of cold atom systems are being developed, for example in the development of precision measurements based on atomic clocks or atom interferometers.This project will be focused on the use of microscopic traps based on atom chips for precise and spatially highly resolved control of ultracold degenerate and near degenerate quantum gases. The scope of the experimental proposal includes two main research directions that will be closely intertwined from the technical point of view, while aiming at quite different physical goals. The first set of planned experiments will address fundamental questions in general many body physics where the unique possibilities of microscopic trapping and controlling fields near the surface of microchips will be exploited to create specific non-trivial confinement geometries and topologies as well as spatially and temporally varying inter-atomic interactions. The second line of experiments will also be based on the precise and flexible control of cold atoms that is possible near surfaces. However, in this case rather than studying the properties of the atomic systems themselves, the roles will be reversed here, and the atoms will be used to measure processe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Novel MS-based strategies to Discover and Evaluate Cancer Biomarkers in urine: Application to Diagnosis of Bladder Cancer' in the context of a Seventh Framework call.

assistant: **Objectives**

In clinical studies, proteomics and transcriptomics allow the comparison of samples from different patients and hold special promise for the discovery of novel biomarkers and the development of “personalized medicine” approaches. Yet, translating recent discoveries into daily medical practice takes time and despite intensified researchers’ interest and investments, the rate of introduction of novel biomarkers in clinical practice is extremely disappointing. The main aim of DECanBio is to implement a strategy for protein biomarker discovery and validation relying on the use of “state of the art” mass spectrometry instrumentation for quantitative analysis of proteins. For the first time, the potential of MRM-Mass Spectrometry (MRM-MS) will be tested in the scope of a large scale validation protocol of cancer protein biomarkers. This analysis will be performed in parallel to the application of miniaturized high-throughput ELISA tests for protein quantification. DECanBio strategy will be applied to issues related to bladder cancer. Specifically, a restricted number of urinary protein biomarkers enabling the detection of recurrences during the monitoring period of patients treated for bladder tumour will be validated.  The work will be performed in priority for the follow-up of low-grade superficial bladder tumours (Ta stage), which, after initial resection (without BCG therapy), are likely to evolve towards remission, recurrence, or progression to a high-grade tumor. The MRM and ELISA tests developed herein aim at the high-throughput quantification of these markers in urine.  Collectively, the project has the ambition to settle a whole experimental pipe-line, from the search for new bladder cancer biomarker candidates, to their thorough evaluation and validation in clinical
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Tool technology for high accuracy micro Part Stamping' in the context of a Fourth Framework call.

assistant: **Objectives**

Objectives and content Miniaturisation of technical products is an item, which is aimed in many industrial areas. A major criteria for this progress is the availability of cheap and high quality manufacturing methods for the mass production of metal micro parts. The presently applied technologies for the production of micro parts (e.g. etching) are expensive, time-consuming and have a high environmental load. Fast, flexible and cheap technologies for the mass production of micro parts should be improved or developed so that Europe can keep up with other high industrialised countries, especially Japan, and to make it competitive with low wage countries. The aim of the Consortium is to develop new techniques and to integrate them into the stamping process to enable this method as a fast and low costs industrial process for the production of metal micro parts. The target is to achieve dimensions and accuracies of micro parts, which today can only be reached by very expensive processes, such as LIGA. The resulting micro-parts can be applied to a range of products, such as:  all kind of connectors for Electronic applications (e.g. lead frames).  watch parts.  parts for consumers, (e.g. razors with thin membranes).  parts for medical applications (e.g. tools for minimal invasive therapy).  parts for micro-systems. The method is applicable in every sector of industrial production where less expensive and metal micro-parts with structure sizes down to 100 mm and accuracies less than 5 mm are necessary. To obtain the desired accuracy in an industrial production process, all influencing parameters of the stamping process have to be investigated. Those are:  tool technology, esp. hybrid tools.  process conditions with flexible tool set up.  new and improved materials for tools and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Wave flume canal de investigacion y experimentacion maritima ii' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

The CIEM flume of LIM/UPC is one of the largest wave flumes in the world for experimentation in the field of maritime and coastal engineering. Its dimensions (100 m length, 3 m width and 5 m depth) and performance make it a very suitable tool for experimental analyses close to the full-scale. The wave flume is indoors and can, thus, be operational independently of weather conditions. The wave generation system is based on a wedge-type wave generator, capable to reproduce waves with heights up to 1.5 m. The control software allows the generation of regular, irregular and solitary waves, and the absorption of waves reflected inside the flume. The measuring equipment available comprises twin-wire resistance wave gauges, pressure transmitters, electromagnetic S-type 2-component current meters, PC-controlled bottom profiler, video image analysis, ADCP and PIV.Researchers interested in apply for access should submit a proposal, including: Objectives / Motivation of the research project /Work programme / Name and nationalities of the proposers (User Group) / An estimation of required days of use o f the facility. The proposals will peer reviewed by a joint independent Users Se lection Panel. During the contractual period, 48 days of access to the facility are offered. Project manager: Prof. Agustín Sánchez-Arcilla Laboratorio d'Ingenieria Maritima C/Jordi Girona 1-3 Campus Nord-UPC, Mòdul D-1 08034 Barcelona Spain Tel: +34-93-4016468 Fax: +34-93-4011861 E-mail: agustin.arcilla@upc.es
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'A Novel Level for the Regulation of Eukaryotic Gene Expression: Coupling Transcription to Translation' in the context of a Seventh Framework call.

assistant: **Objectives**

Eukaryotic gene expression is a highly regulated, fundamental cellular process encompassing distinct steps such as transcription, mRNA processing and nuclear export, translation and degradation of the mRNA. In this project a novel level in the regulation of gene expression will be analyzed. We propose that transcription and the correct processing as well as packaging of the newly synthesized mRNA into an mRNP control the translation of this mRNA in the cytoplasm thus coupling intranuclear events in mRNA biogenesis to translation. Recently, we showed that the transcription elongation factor Ctk1 functions as a positive factor in translation elongation by phosphorylating the ribosomal protein Rps2. According to our model, Ctk1 enhances the translation fidelity of mRNAs that have been correctly processed and assembled into mRNPs in the nucleus. In the project proposed here we will analyze how the function of Ctk1 couples transcription to translation and how Ctk1 functions in translation initiation, in support of which we have already obtained evidence. Importantly, we will identify additional players in coupling intranuclear mRNA biogenesis events to translation and unravel their molecular function. In addition, we will determine phosphorylated residues on ribosomal proteins and translation factors, identify their kinases and phosphatases, and analyze the biological significance of these phosphorylation events in translation. Moreover, the conservation in higher eukaryotes of the biological principles obtained with our model organism S. cerevisiae will be assessed. All these experiments are performed under the aspect that the cell uses phosphorylation of ribosomal proteins and translation factors to control the efficient and correct translation of a correctly processed mRN
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Structural studies of mammalian Cys-loop receptors' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

In the brain, Cys-loop receptors mediate fast neurotransmission. They function as allosteric signal transducers across the plasma membrane: upon binding of one or more neurotransmitter molecules to an extracellular site, the receptors undergo complex conformational transitions that result in transient opening of an intrinsic ion channel. The Cys-loop family comprises receptors activated by serotonin, acetylcholine, glycine and GABA. Mammalian receptors are also the targets of a legion of psycho-active and therapeutic compounds (including nicotine, benzodiazepines, anti-emetics, general anaesthetics). Our structural knowledge is currently limited to invertebrate homologues. Atomic structures mammalian receptors are therefore acutely missing in order to understand their physiological role in molecular terms, and to be able to develop new drugs targeting them. The project proposes to decipher the operation mechanism, the pharmacology and conformational transitions of mammalian Cys-loop receptors. Starting with a solid body of preliminary results, we will obtain new high-resolution structures, taking advantage of antibody-based crystallization chaperones. We will try and record for the first time a ‘molecular movie’ of the gating conformational transition in cristallo. On the way, we will also investigate the potential of antibody-based modulators of Cys-loop receptors for biomedical applications.The applicant has solved in the past the structures of a bacterial Cys-loop receptor and of the mouse serotonin receptor. The proposed research will take place at the CNRS in Grenoble, France, in a very favourable environment for structural biology.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The origin of the Galactic magnetic field' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Magnetic fields lie at the heart of essentially all the outstanding problems in galactic evolution. However, the measurement of interstellar magnetic fields is very challenging.  We can either measure the strength or the direction of the magnetic field vector in different regions of the Milky Way.  Clearly, in order to assess the impact of the magnetic field in the core processes of galactic evolution, such as star formation and stellar feedback, we need to complement the observations with simulations of the magnetic field evolution.The most successful simulations of the galactic magnetic field evolution show that tiny magnetic seeds of cosmic origin were amplified to their current values through a dynamo process. In a dynamo, large-scale galactic processes such as differential rotation and turbulence twist magnetic field lines, and small-scale processes like Ohmic diffusion reconnect them.  However, simulations of this process so far lack the simultaneous modeling of the processes that generate turbulence and the realistic small-scale diffusion that drives the dynamo.This ambitious project will develop the first simulations that will include all the core processes of galactic evolution, such as a multi-phase interstellar medium, time-dependent star formation and stellar feedback, and the realistic non-ideal MHD terms necessary for modeling a dynamo.  The simulations will be performed with the RAMSES code, a throughly tested tool for galaxy evolution simulations.  The Adaptive Mesh Refinement technique employed in the code will allow capturing the self-consistent generation of turbulence by stellar feedback, and its zoom-in capabilities will allow re-simulating regions of interest with enough resolution to model the magnetic field diffusion.The outcome will be the first
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Nanoparticle Enhanced Molten Salts for Solar Energy Storage'.

assistant: **Innovation**

Thermal energy storage is a useful method to adjust temporal mismatch between the demand and supply of solar energy systems, and latent thermal energy storage (LTES) using phase change material (PCM) has drawn increasing attentions for its high energy storage density and small temperature variation. Molten salt is a promising candidate for solar energy storage media at middle temperature range (140~300 oC). However, the low thermal conductivity of pure salt hampers the development of this technology. This proposal aims to introduce high conductive nanoparticles (NP) to improve the stability and thermo-physical properties of conventional PCMs for solar energy storage, termed as NPMSSES. Molten salts will be used as the matrix, and NPs (i.e., nickel, graphite platelet nanofibers and graphene) or expanded graphite (EG) will be introduced. It is a highly challenging yet exciting project that unites and advances the boundaries of three state-of-the-art disciplines: functional nanoparticles / nanocomposite, solar energy storage, and multiscale modelling. This work will address four main tasks: i) synthesis and characterization of NP-PCMs with good stability ii) identification thermo-physical properties of NP-PCMs under high temperature; iii) investigating their operational and heat transfer characteristics in a LTES system, including shell-tube and fluidized bed types, and iv) multiscale modeling thermo-physical properties of composite PCMs. My strong experience in experimentation with PCM and heat transfer and the vast knowledge on advanced nanomaterials synthesis and characterisation, and multiscale modelling of the host university will create the optimal environment to deliver the objectives of NPMSSES. The fellowship will be highly beneficial to establish myself as an ind