RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Mapping, monitoring and modelling land use and land cover change in the Mediterranean region using remote sensing and ancillary data in a GIS framework' (2002-2006).

assistant: **Concept**

Alterations in the Earth's surface hold major implications for the global radiation balance and energy fluxes, contribute to changes in biogeochemical cycles, alter hydrological cycles, and influence ecological balances and complexity. It is widely recognized that an understanding of land use and land cover (LULC) changes is central to the debate of sustainability. In terms of the Mediterranean region, it has been widely documented that, over the last decades, the area has been subjected to a large number o f changes. These have often been linked to the increase in erosion, desertification and land degradation observed in large parts of the region and a need for continuous observation and monitoring has been identified.However, for all its importance to scientists and policy-makers confronting the complexities of environmental change, LULC change is still poorly understood. Remote sensing (RS) provides cost-effective multi-spectral and multi-temporal data, valuable for understanding and monitoring land development patterns and processes and for building LULC data sets in a GIS framework which provides a flexible environment for storing, analysing, and displaying digital data necessary for change detection and database development. Nevertheless, although the linkage between RS and GIS techniques has become mature over the last years, only a few LULC change studies have attempted to link RS and GIS to modelling methods, such as Markov chains, cellular automata, neural networks or statistical logistic regression.This missing linkage has hindered modelling and assessing the dynamics of LULC change, and significantly impeded progress towards understanding of earth' atmosphere interactions, biodiversity loss, and global environmental change. This project will seek to develop
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Search for novel molecules cross-talking between muscle and cancerwith therapeutic potential against cachexia and cancer' (MUSCLEANDCANCER) under Seventh Framework.

assistant: **Objectives**

Cancer cachexia is a life-threatening syndrome characterized by severe body weight loss, due to depletion of adipose tissue and skeletal muscle, and affects up to 80% of patients with advanced cancers. The rapid loss of muscle mass is the main cause of function impairment, fatigue and respiratory complications, leading to death in 20-48% of cases. To date, no effective treatment is available. By using Ingenuity Pathways Analysis software, I have analyzed the cancer cachexia-specific genes, found previously by others, and discovered a specific signaling pathway altered in muscles of cachectic rats. By over-expressing and repressing genes of this pathway in in vitro (adenoviral infection of myotubes) and in vivo (muscle electroporation of plasmids in mice) approaches, I will dissect the role of this signaling cascade during cachexia. Since agonists and antagonists for this pathway are already available, they will be also tested for their possible protective effects against cancer cachexia. Physical activity extends life span of cancer patients and correlates with lower incidence of many cancers but its modes of action are still unclear. The concept that muscle is an endocrine organ able to release molecules (myokines) is quiet new and opens exciting fields to explore. Interestingly, the unique resistance of muscle to cancer and metastasis makes reasonable that anti-cancer myokines may exist. Their secretion especially during physical activity could explain why exercise protects from cancers and retards its progression. So, I propose to search for novel anti-cancer molecules from exercised muscles by taking advantage of adenoviral infection of myotubes to express molecules able to mimic some of the effects of (strength or endurance) exercise. The isolation of anti-cancer m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Potential-dependent Second-Harmonic Generation  in Optical Antennas measured Time-resolved' (PoSHGOAT) under Horizon 2020.

assistant: **Objectives**

Second-harmonic generation (SHG) is a nonlinear optical effect, with promising applications in background-free spectroscopy, ultrafast optical switching, and optical information processing. What is missing is the integration of these effects at the nanoscale, to be sensitive down to the singe molecule level and competitive in size with silicon electronics.Metallic nanoparticles, called optical antennas (OAs), show resonances in the infrared and optical wavelength regime. They exhibit plasmons, coupled states of photons and electron density waves, which allow concentrating light much better than conventional optics, down to 10 nm³. OAs enable SHG in nanometer-sized volumes, but until now only with low efficiency. This is due to the complex task of: (i) a resonance to receive light with wavelength A, (ii) routing the energy to the OA surface (efficient SHG due to symmetry breaking), (iii) exploiting a second antenna resonance which can gather the SHG at wavelength B=A/2, and finally (iv) emitting the wavelength B to the far field.In the proposed project PoSHGOAT I will control and optimize SHG in OAs. To this aim, I will introduce four novelties to SHG research:(1) Fabrication of electrically-contacted nanoantennas with ultra-fine tips (r = 3 nm) and ultra-narrow gaps (g = 3 nm) by a subsequent Ga-ion and He-ion milling procedure.(2) Modulation of the surface charges in metallic nanoparticles by applying an external potential.(3) Time-resolved pump-probe spectroscopy of SHG with an applied voltage, eventually even with induced tunnelling of electrons in a highly asymmetric antenna gap. This will establish ultrafast control over the OA surface charge density and, thus, SHG.(4) Numerical modelling of SHG and evolutionary optimization of nanoparticle geometries to maximize S
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Continuous Annular Electro-Chromatography', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Capillary electrochromatography (CEC) combines the high separation efficiency of capillary electrophoresis with high performance liquid chromatography (HPLC) and provides a powerful tool for the separation of a wide range of both neutral and charged components. The proposed integration of this technology and the rotating system of annular chromatography into a continuous annular electrochromatography (CAEC) would increase the throughput up to 20,000 times whilst maintaining an efficiency of more than 100,000 theoretical separation stages per meter. This extends the range of applicability from analytical purposes towards safe and flexible ultra small-scale production of extremely high-value-added products early on in the development stages. The project is thus expected to significantly enhance the sustainability of pharmaceutical and chemical production by providing equipment for highly intensified purification processes.  The development of CAEC units as a new generation of extremely flexible high-performance process equipment requires specialised engineering skills and high-precision manufacturing techniques. A wide range of applications will be offered by the development of tailored stationary phases while an improved understanding of the complex processes occurring at different scales is used to model the performance of the CAEC system. An elaborated prototype including on-line sensors and a sophisticated process control concept will be developed and validated under industrial conditions during a demonstration phase. This will guarantee a fast uptake of the projects results and allow for an approved industrial production of the new process equipment within 1 to 2 years after the end of the project. The consortium includes an end user from pharmaceutical industry to e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Embodied and communicating agents' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

The project proposes visionary and high risk research that will provide better understanding of the role of communication in collections of embodied and situated agents using the methodological and theoretical tools of complex systems science and computer science. We aim at studying how communication arises, what different types of communication systems there are or can be, what the different pre-conditions are that must be satisfied for the emergence of different types of communication systems, what kind of new performances at the collective level are made possible by different communication systems, what is the role of the communication network topology in such performances.The project will investigate basic properties of different communication systems, from simple communication systems in animals to human language and technology supported human communication, to clarify the nature of existing communication systems and to provide ideas for designing new technologies based on collections of embodied and communicating devices. The aim of the project is the development of a new generation of embodied agents that are able to interact directly (i.e., without human intervention) with the physical world and to communicate between them and with other agents (including humans). This will be achieved through the development of new design principles, algorithms, and mechanisms that can extend the functionality of existing technological artefacts (mobile phones, Wi-Fi devices, robots and robot-like artefacts, etc.) and can lead to the development of new artefacts exploiting the characteristics of ECA gents.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Printable polypeptide hydrogels with antimicrobial properties' (GelPrint) under Horizon 2020.

assistant: **Objectives**

Biomaterials with antimicrobial properties which can be used for wound healing and tissue engineering applications offer high application potential due to the global increase of antimicrobial resistance. While polypeptides own this potential, their integration into a materials platform has not been realised to date. The overall objective of this project is to develop 3D printable antimicrobial or bacteriostatic polypeptide hydrogel materials, which can be employed in tissue regeneration applications to prevent bacterial growth. In particular, the goals include synthesis of sets of cross-linked polypeptide hydrogels based on lysine (Lys) and investigation of their hydrogel properties and 3D printability. Moreover, evaluation, validation and quantification of the antimicrobial properties of the hydrogels as well as the proof of concept demonstration for their feasibility in tissue regeneration will be addressed. The synthesis of these particular copolypeptides hydrogels is highly novel and their exploitation as a printable tissue regenerating platform is timely, of high fundamental as well as clinical impact and considered a new approach. The proposed project is broadly interdisciplinary, as disciplines of polymer chemistry, biomaterials science and engineering, microbiology and in vitro assessment techniques will be combined. The high-level science combined with complementary training will significantly advance the career opportunities of the applicant. Moreover, the excellent match of the applicant`s expertise with the project and the host organisation will ensure a strong transfer of knowledge between all participants. The potential of the proposed project is further highlighted by the possible commercial exploitation of the scientific findings and developments. Finall
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Participatory Designing with Sound' (PaDS), addressing dissemination and exploitation.

assistant: **Impact**

Today’s sonic displays play a significant role in threatening the quality of our everyday lives, personal and professional.Consequently, the interest to design sound is shifting from crafting the sound towards collaboratively understanding the role ofsound and its position in complex environments, such as healthcare and autonomous driving, in which humans and technologymust co-exist. Accordingly, the design process requires more inclusive, human-centered and technology-driven approaches todesign sonic experiences. Yet the field of industrial design lacks systematic design methods and tools to empower design teamswhen they collaboratively express creativity through sound and discover sound-driven engineering solutions. Thus, with the PaDS(Participatory Designing with Sound) project, I aim at advancing the knowledge on sound-driven design thinking in which soniccommunication (speaking about sound and experiences, imagining and representing them) is especially required within multistakeholder design teams that consist of expert (sound) designers as well as non-experts (e.g., users, manufacturers, policy makers).The main goal of PaDS is opening sound design practices to participatory approaches, in which stakeholders are involved in thedesign process as partners. The core of this project is the development of methods and representational tools to empower designersand other stakeholders to collaboratively conceptualise, express, and communicate sound-driven designs. To reach its goal, thePaDS project is based on a mixture of interdisciplinary approaches, including sonic interaction design, design cognition studies, andexperimental psychology: Applied research and contextual inquiry of sound issues in complex, socio-technological environments provide relevant case studies of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Microbial sulfonolipid biosynthesis and degradation in the human gut' (SLIDES) under Horizon Europe.

assistant: **Objectives**

Sulfobacins are sulfonated lipids that are bacterially synthesized in the gut and modulate the immune system and dampen intestinal inflammation. Therefore, they are considered as potential therapeutics for targeted microbiome-oriented interventions in the increasing number of cases of inflammatory bowel disease. However, the effects of sulfobacins on the gut microbiota, the degradation processes, and the key enzymes of the microbial biosynthetic pathway are unknown. The complex human gut microbiota directly affects host health by influencing the abundance of metabolites, aiding in nutrient digestion, protecting against enteropathogens, and enhancing immune system activity. Dysbiosis is usually associated with disease and intestinal inflammation. It is a crucial prerequisite for microbiome-oriented interventions to elucidate the ecophysiology of the species that drive these pathways. The existence of sulfobacin decomposition has not been shown yet in any habitat but sulfonated lipid degradation is usually correlated with increased availability of reduced sulfur compounds, which can also act as signaling molecules. Thus, project SLIDES aims to discover the species and that drive the degradation in the human gut and the biosynthesis pathway. This will be accomplished by a combination of molecular biology and functional microbiome analysis methods. This will result in: (1) the elucidation of the sulfobacin biosynthesis pathway and its genes by reverse genetics, (2) the discovery of sulfobacin degraders and the impact of sulfobacins on the gut microbiota by monitoring the temporal dynamics of responsive taxa, metabolic activity, and metabolite changes in sulfobacin-stimulated human fecal microcosms, and (3) the description of ecophysiology of sulfobacin degrading species, th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Development of high entropy ceramic-polymer composite by ultra-low temperature sintering for high-frequency related applications' (HECPC) under Horizon Europe.

assistant: **Objectives**

The search for microwave materials with tailored dielectric properties in millimeter-wave frequencies has been the objective of a significant number of manuscripts reported in the literature. Dielectric ceramics with low-loss dielectric, thermally stable and low permittivity have received extensive attention owing to their significant application prospects in microwave communication systems. It is therefore desirable to introduced new production techniques, new compositions or improves the properties. The proposed research will intellectually contribute to the scientific literature through the preparation and characterization of new dielectric materials belonging to the diopside CaMgSi2O6 based ceramics. This proposal seeks to achieve the following specific objectives: (1) Consideration of the impact of different types and concentrations of dopant such as Sr and Ba for large divalent cation (Ca) and Zn, Co, Mn and Ni for small divalent cation (Mg) via high entropy strategy on the structural, microstructural and microwave dielectric characteristics of CaMgSi2O6 based ceramics. (2) Evaluation of the effect of thermal annealing time and temperature on the final performance of high entropy CaMgSi2O6 based ceramics. (3) To explore the relationship between high entropy design and microwave dielectric properties. (4) Fabrication of CaMgSi2O6  Polyethylene (PE) composites using cold sintering process and investigation of the pressure, temperature and transient solvent type on densification, microstructure and microwave dielectric properties. State of the art and new experimental techniques and methods will be used in order to achieve the goals of this proposal.


**Keywords:** Electroceramics, Ceramic Processing, Structural and Microstructural Properties, Dielectric Properties
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Lifting Methods for Global Matching Problems'.

assistant: **Concept**

This proposal presents a research program aimed at breaking new ground in theoretical, algorithmic and practical aspects of the notoriously difficult matching problems. The main goal is developing a unified algorithmic framework for matching problems that enjoys theoretical guarantees and high practical value for ``real-life'' applications.The core methodological aspect is the modelling of matching problems as high-dimensional, lifted convex problems that can be efficiently approximated. We present several case-studies of this methodology, constructing efficient algorithms for approximating the solutions of important instances of the matching problem. The results already demonstrate state of the art performance and are backed-up with novel theoretical analysis proving tightness and correctness of the suggested convexifications for certain classes of non-trivial input.This proposal has ``high risk - high impact'' profile: The ``high-risk"" aspect of this proposal comes from the hardness of general matching problems which, when faithfully represented, are NP-hard. However, as we demonstrate, combining convex optimization tools in a careful way, that takes into account computational complexity, is likely to push forward the limits of current algorithmic solutions. The ``High-impact"" will be immediate: As matching problems exist in almost every aspect of scientific research, practical generic algorithms for matching problems are likely to have a significant influence.We believe that the inroads and preliminary results presented in this proposal already provide strong evidence for the potential success of the suggested research program.""


**Keywords:** Shape matching, non-rigid matching, geometry processing, shape analysis