RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'A fungi-based biotechnological platform for competitive multi-stream waste revalorization.' (WASTE2WEALTH) targeting Horizon Europe.

assistant: **Abstract**

The EC’s Circular Economy Action Plan targets textiles as one of the sectors to be drastically transformed into a circular economy. However, the recycling of textile waste is severely limited by the need to accurately separate the different types of fibre, as they require separate recycling processes. This results in most of it currently being incinerated or landfilled.At Novobiom, we valorise widely available resources currently under-exploited by harnessing the amazing ability that fungi exhibit in nature to recycle a wide range of materials. Our biorefinery platform implements a tailored solid-state fungal fermentation process, based on our exclusive fungal strain bank and fungal strain selection, development and optimisation process.Our first application focuses on textile waste. By valorising unused textile waste, we offer a cost-effective alternative to recycle mixed waste streams, drastically reducing the textile products incinerated or sent to landfill while producing high-quality products (biosurfactants to substitute chemical-based surfactants, enzymes and biogas) at lower prices. These products are of interest in various industries (cosmetics, cleaning products, etc.).During the project we will build a fungal biorefinery pilot plant (200 t/yr), operated with textile waste. After that, we will engineer and commission a flagship demo plant (12,000t/year). This will de-risk the project enough to open an investment round to finance the scale-up of the technology.Once scaled, our biorefinery can enable the transformation towards circularity of complex waste streams and fulfil the needs of different customers (e.g. textile, cosmetics) with affordable high-quality sustainable biomaterials.


**Keywords:** bio-remediation, fungal strain, waste management, circular ec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Quantifying the spread of P. falciparum malaria', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Background: A major challenge for malaria elimination is its phenomenally efficient spread through sexual stage parasites (gametocytes). Many individuals in endemic settings harbour low but transmissible gametocyte densities. It is currently unclear how gametocyte density translates into the likelihood that an infected mosquito gives rise to secondary infections, who drive malaria transmission at population level and how anti-gametocyte immunity affects gametocyte production and infectivity. I hypothesize that secondary infections can arise from low-density infections but that higher gametocyte densities result in comparatively more infectious mosquitoes and an increased number of secondary infections. I further hypothesize that malaria transmission efficiency and changes therein can only be accurately predicted if anti-gametocyte immunity is thoroughly understood and that the rapid loss of gametocyte immunity during effective control results in increased transmission efficiency.Aims and approach: I will perform the first-ever direct assessment of numbers of malaria parasites ejected by mosquitoes in relation to natural gametocyte densities. Using novel genotyping approaches, longitudinal sampling of infections at unsurpassed resolution and state-of-the art analytical approaches, I will perform the most comprehensive molecular evaluation of malaria transmission in a real community ever performed. Lastly, I will quantify the impact of immune responses that reduce gametocyte density and infectivity by novel immune-profiling approaches and mathematical transmission models.Importance and innovation: this project will profoundly improve understanding of the production and infectivity of gametocytes and the epidemiological impact of human immune responses that influence these
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'PASSERINE BIRD EVOLUTION AND BIOGEOGRAPHY' (BirdEvoBioGeo).

assistant: **Innovation**

Islands and archipelagos have fascinated ecologists and biogeographers for centuries. As natural evolutionary laboratories that have distinct boundaries and come in all sizes, they are ideal for testing theories about evolution, biogeography and ecology. The Indo-Pacific region constitutes the largest concentration of islands and archipelagos on the planet providing an ideal setting for testing such theories. This project will focus on a large radiation of passerine birds, the core Corvoidea (crows and allies). The core Corvoidea originated in the mid-Tertiary in Australia, from where members dispersed into the Indo-Pacific archipelagos and onwards to other continents. Today the core Corvoidea is a very successful group in terms of distribution and species numbers, occurring in the Indo-Pacific as well as on all continents. Until recently, little molecular data was available for the group, hampering ecological, evolutionary and biogeographical analyses and interpretations. However, this has changed dramatically and molecular phylogenies now exist, including roughly about 85% of all the species. With this molecular data in hand there is an unprecedented possibility of actually testing evolutionary and biogeographical ideas and theories about the history of this group and the reasons for its success with state-of-the-art evolutionary and ecological statistical tools and software. Imperial College London has a great tradition of using large datasets and phylogenies to answer questions pertaining to patterns of diversity, evolution, community assembly and biogeography. Thus, the combination of a well resolved and well sampled molecular framework including more than 700 passerine bird species, and an institution with a history of using advanced bioinformatic and statistical
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Overcoming the curse of dimensionality through nonlinear stochastic algorithms'.

assistant: **Objectives**

In a series of relevant real world problems it is of fundamental importance to approximatively compute evaluations of high-dimensional functions. Such high-dimensional approximation problems appear, e.g., in stochastic optimal control problems in operations research, e.g., in supervised learning problems, e.g., in financial engineering where partial differential equations (PDEs) and forward backward stochastic differential equations (FBSDEs) are used to approximatively price financial products, and, e.g., in nonlinear filtering problems where stochastic PDEs are used to approximatively describe the state of a given physical system with only partial information available. Standard approximation methods for such approximation problems suffer from the socalled curse of dimensionality in the sense that the number of computational operations of the approximation method grows at least exponentially in the problem dimension. It is the key objective of this project to design and analyze approximation algorithms which provably overcome the curse of dimensionality in the case of stochastic optimal control problem, nonlinear PDEs, nonlinear FBSDEs, certain SPDEs, and certain supervised learning problems. We intend to solve many of the above named approximation problems by combining different types of multilevel Monte Carlo approximation methods, in particular, multilevel Picard approximation methods, with stochastic gradient descent (SGD) optimization methods. Another chief objective of this project is to prove the conjecture that the SGD optimization method converges in the training of ANNs with ReLU activation. We expect that the outcome of this project will have a significant impact on the way how highdimensional PDEs, FBSDEs, and stochastic optimal control problems are solved
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'A medical device for airflow simulation of the human upper airways' (NASALFLOW).

assistant: **Concept**

Nasal airway obstruction (NAO) can be defined as nasal ventilatory difficulty of a patient that is unable to achieve enough air volume in the upper airways to keep a quiet breathing without perception of obstruction or resistance. From 30% to 40% of population suffer from NAO, 259 million people in Europe alone. Some of the patients suffering nasal diseases need to undergo surgery, a procedure that is potentially hazardous for the patient, but also very expensive for patients and governments. The value of the worldwide medical technology market will reach €458.7bn by 2022, growing at a rate of 5.1% per year between 2016 and 2022. Nowadays, the most used tests by the clinicians are Peak nasal inspiratory flow, Acoustic Rhinometry and Rhinomanometry. These tools are rarely used in clinical practise due to its limitations. Hence, there is an upcoming need for new objective and accurate technologies that provide more detailed information about the airflow patterns inside nasal cavity. The revolutionary NASAL~ FLOW® is an automatized medical device based on the Computer Fluids Dynamics (CFD) analysis of human nasal cavities. A standardised procedure is set to study systematically the flow patterns of each patient and provides a huge amount of medical information that traditional methods are not able to obtain. In addition, it embedded a Virtual Surgery tool (VS), where several surgery methodologies can be assessed computationally without invasive procedures for the patient, saving time and money for health system. This approach will help in diagnosis and surgical planning for nasal diseases.N.A.S.A.L. is a Spanish SME founded in 2008, dealing with the improvement and updating of the medical procedures used in the Ear, Nose and Throat field and the patients’ well-being, throu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Exploring and exploiting the potential of extinct genome sequencing' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Palaeogenomics is the nascent discipline concerned with sequencing and analysis of genome-scale information from historic, ancient, and even extinct samples. While once inconceivable due to the challenges of DNA damage, contamination, and the technical limitations of PCR-based Sanger sequencing, following the dawn of the second-generation sequencing revolution, it has rapidly become a reality. Indeed, so much so, that popular perception has moved away from if extinct species’ genomes can be sequenced, to when it will happen - and even, when will the first extinct animals be regenerated. Unfortunately this view is naïve, and does not account for the financial and technical challenges that face such attempts. I propose an exploration of exactly what the limits on genome reconstruction from extinct or otherwise historic/ancient material are. This will be achieved through new laboratory and bioinformatic developments aimed at decreasing the cost, while concomitantly increasing the quality of genome reconstruction from poor quality materials. In doing so I aim to build a scientifically-grounded framework against which the possibilities and limitations of extinct genome reconstruction can be assessed. Subsequently genomic information will be generated from a range of extinct and near-extinct avian and mammalian species, in order to showcase the potential of reconstructed genomes across research questions spanning at least three different streams of research: De-extinction, Evolutionary Genomics, and Conservation Genomics. Ultimately, achievement of these goals requires formation of a dedicated, closely knit team, focusing on both the methodological challenges as well as their bigger picture application to high-risk high-gain ventures. With ERC funding this can become a realit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Simulating the effects of low-carbon investments in electricity markets' (NextENERGEIA) under Horizon Europe.

assistant: **Objectives**

NextENERGEIA plans to develop and test a proof-of-concept prototype of an analytical tool for simulating the social and private impact on power markets of low-carbon investments (renewable energies, energy storage, electric vehicles, and hydrogen production). The tool would shed light on issues central to the energy transition’s success, making it precious for regulators, policymakers, energy-intensive consumers, and energy firms. In particular, the tool would be instrumental in informing the current policy debate on the electricity market reform. The tool would build on state-of-the-art game-theoretical models developed by the PI through her ERC Consolidator Grant ELECTRIC CHALLENGES, providing the basis to simulate firms’ competitive and strategic behavior in electricity markets with large shares of renewable energies and energy storage. Those models also serve to assess the low-carbon investments’ impact on several metrics reflecting electricity market outcomes (prices, market shares, emissions, etc.) and firms’ financial profitability (pay-back period, NPV, IRR, etc.) The algorithm would be programmed in Python, and an internet-based interface would be developed for ease of use. Data from the Spanish electricity market would be used to test the tool, which would be further extended to other European power markets. Relevant stakeholders in the sector have already shown their support and willingness to participate in the training and testing stages. The team comprises the PI (Natalia Fabra), postdocs at EnergyEcoLab (the research lab she created under her ERC grant), and software programmers who would carry out the programming activities. The team combines a deep knowledge of the power sector and the energy transition policies, a deep understanding of the relevant eco
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Biosafety evaluation of probiotic lactic acid bacteria used for human consumption'.

assistant: **Objectives**

Probiotic bacteria, mainly lactic acid bacteria (LAB) (e.g. lactobacilli, iactococci, enterococci, and bifidobacteria) have been considered safe for human consumption. However, recent reports of clinical infection, the spread of antibiotic resistance genes, and development of new and/or modified probiotic LAB strains, have caused concern of safety. This project aims to assess the biosafe of LAB. Isolates from healthy humans and immunocompromised patients, commercially available and new probiotic LAB will be studied.After polyphasic taxonomic identification, their biosafety will be assessed by:(i) the detection of antibiotic resistance and horizontal transfer of antibiotic resistance genes;(ii) the detection of known and new virulence properties;(iii) evaluation of immunological adverse effects of LAB; and(iv) the survival, colonisation, and genetic stability of probiotic LAB in the human gut.The project will result in recommendations for biosafe and biosafety testing of LAB, which will be presented and discussed at a final conference.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Advanced mipas level-2 data analysis' (AMIL2DA).

assistant: **Innovation**

Problems to be solvedChanges in atmospheric composition are important in the context of stratospheric ozone depletion, global change and related environmental problems. The Michelson Interferometer for Passive Atmospheric Sounding (MIPAS), which is a core instrument of the Envisat polar platform to be launched in 2001 by the European Space Agency (ESA), is a powerful tool to measure vertical profiles of trace species on a global scale. While operational data processing by ESA covers only analysis of pressure, temperature, and the mixing ratios of the species O3, H2O, HNO3, CH4, and N2O, MIPAS infrared spectral limb emission measurements contain information on a bulk of further species relevant to environmental problems mentioned above. The goal of AMIL2DA is to generate data analysis tools for these supplemental species along with thorough validation of these algorithms.Scientific objectives and approachInstead of merging the contributions of all participants to one data analysis algorithm which fits all purposes, the AMIL2DA strategy is to maintain the diversity of different computer codes by each group which are custom-tailored to their specific scientific needs. Generally, data analysis consists of forward modelling of radiance spectra and inversion of measurement data. As a first step, forward radiative transfer algorithms and retrieval processors are adapted to the physical and computational needs of the MIPAS experiment. This includes adaptation to high resolution limb emission measurements, acceleration of numerical methods, and automated provision of input data as well as generation of spectroscopic line data not included in the current databases but presumably important to MIPAS applications. In a second step, these codes are cross-validated by a blind-test int
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Distributed Transmission for Cooperative Multiuser Multiple-Input Multiple-Output (MIMO) Systems' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Multiple-input multiple-output (MIMO) systems have become an important area of research, as they are shown to enable high data rate communications with great reliability over the wireless link. In particular for cellular networks, MIMO techniques are promising for achieving high capacity by exploiting the spatial and multi-user diversities inherent in the channel. In a MIMO cellular system, it is possible to further enhance the system capacity through cooperation.The aim of this work is to investigate the feasibility of and characterize the gains from base station (BS) cooperation and develop cooperative transmission schemes for the downlink of a MIMO cellular system, where the base stations cooperate in the transmission of information to the users in the system. To characterize the gains from BS cooperation, the asymptotic growth rates of the system capacity with the number of users and the number of BS antennas will be derived and compared for systems with and without BS cooperation. In the case of BS cooperation, the system can be modelled as a single cell MIMO broadcast channel. Therefore, recent results in the literature on MIMO broadcast channels (BC) can be utilized. However, the extension of MIMO BC results to cooperative systems requires cooperation of all base stations, which is not feasible for practical cellular systems. Thus, it is of interest to investigate distributed transmission schemes that can be implemented with local information exchange between the neighbouring base stations.In this work, information-theoretic limits of such schemes will be studied and novel distributed transmission algorithms for cooperative MIMO cellular networks will be developed. The performance of these algorithms will be studied through computer simulations. The results of th