RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Development of a cost-effective, durable coating system with low fungicide content for wood surfaces using Plasma Discharge' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

For wood to compete with other materials and be attractive to customers, a durability of treated wood facades of at least 5-8 years renovation-free should be guaranteed. New EC legislation (2004/42/EC) requires the replacement of solvent-borne coating systems with water-borne coatings for outdoor wood preservation purposes. Wooden facades treated with water-borne coatings are more susceptible to discolouring and damage by mould and blue stain fungi. Mould fungi grow mainly on the surface of the paint film and harm the appearance of wood surfaces via their pigmented spores. Blue-stain fungi are capable of colonising the surface as well as the wood and wood-coating interface. They can penetrate the coating film enzymatically and mechanically, thereby damaging its protective functioning against the elements, leading to costly repair work after only a few years of service life. In order to sustain the use of wood in the face of growing competition from other materials, a need exists for cost-effective wood protection methods free from toxic preservatives, but which are capable of offering comparing durability.   This project will develop a cost-effective, ecological, high performance wood coating system, offering low fungicide content. It is long known that the interaction of wood with water can lead to dimensional instability and accelerated bio, and weathering degradation. A variety of techniques have been investigated to achieve water repellent characteristics of wood surfaces, from liquid reagents, to thermal and chemical applications. A very promising technique to hydrophobize wood surfaces is the use of electrical gas discharges (plasma). This project will build on past research in this area to arrive at a DURAWOOD system that meets market needs in terms of price, dur
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Ecofriendly synergists for insecticide formulations' (ECOSYN).

assistant: **Concept**

Insect pests cause significant damage to agricultural crops and transmit several important diseases of humans and animals. Chemical insecticides have been used to control insect pests for many decades and remain essential to ensure a supply of affordable food and as part of disease vector control for the foreseeable future. Unfortunately, the world-wide use of synthetic insecticides over many years has led to increased resistance to insecticides and contributed to environmental contamination. One way to reduce insecticide use without compromising control is to use a synergist in combination with an insecticide. Synergists are themselves nontoxic but act by increasing the effectiveness of the insecticides they are used with. They do this by inhibiting the metabolic systems in insects that detoxify insecticides. The goal of this project is to develop ecofriendly synergists for use in formulations with insecticides, both in agriculture and in Public Health, enabling a reduction in the amount of insecticidal active applied, and thereby reducing the adverse effects of these insecticides on beneficial insects such as bees. On the basis of in-depth experimental analyses of the interactions of the known synergist piperonyl butoxide with metabolic enzymes in pest insects, new molecular structures will be designed, synthesized and evaluated on pest and beneficial species using laboratory bioassays and field trials. In addition, the synthesis process to manufacture these synergists will be evaluated with the aim of achieving an industrially and economically feasible process. Finally strategies will be developed that use the novel synergists to enhance the control of insect pests while preserving beneficial insects. As such this research has significant scientific, economic, and so
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Modern and recent sediment gravity flows offshore eastern Sicily, western Ionian Basin' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Submarine sediment gravity flows are some of the most important sediment transport processes globally. They pose a hazard to offshore infrastructure and may contribute to tsunami generation. The behaviour of these sediment flows, however, is still not fully understood. The Ionian Basin offshore eastern Sicily is characterised by high seismicity, tsunamis and gravity flows. The 1908 Messina earthquake, which caused >60,000 casualties, triggered an extensive turbidity current. The geohazard implication of gravity flows is poorly constrained for this densely populated and economically important region. The objectives of MARGRAF are to: 1) reconstruct the behaviour and evolution of the 1908 turbidity current; 2)evaluate the role of this turbidity current in the 1908 Messina tsunami; 3) test the effectiveness of using a submarine telecommunication cable to detect modern gravity flows; and 4) determine present-day probability of new turbidity currents being generated along the eastern Sicilian margin. Addressing these objectives will help to understand key processes involved in submarine gravity flows. The objectives will be fulfilled via a multidisciplinary and multi-scale analysis comprising geophysical and sedimentological data interpretation, numerical modelling, and laser interferometry. The researcher’s expertise in analysing submarine sediment failures will be crucial to implement the project’s objectives. Results will be disseminated to target audiences via different measures (e.g., newspapers). MARGRAF will be carried out at the Department of Geosciences of the University of Malta. Secondments in France and in Germany will provide data and training of relevant skills. By the end of the fellowship the researcher will have new technical skills (e.g., numerical modellin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'TEStis or OVAry: Identifying the molecular and cellular processes controlling sex determination.', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Sex determination is the process that allows the bipotential gonad to develop into a testis or an ovary, thus initiating the sex fate of the individual. In mammals, the supporting cells are the first to adopt a sexual identity and then direct the differentiation of the other gonadal cell types. Despite their key role, we still do not know how these important cells acquire their identity. To address this question, we will use spatial transcriptomics and lineage tracing analysis in combination with mouse models deficient for the RSPO1/WNT/ß-catenin signaling pathway as a we found that absence of Rspo1 impairs supporting cell differentiation. Ovarian determinants are still unknown in most vertebrates, but we have recently identified that an isoform of WT1 is the ovarian determinant, in mice. We will use genetic engineering in chicken and zebrafish to test whether this conserved isoform has a similar function in other sex determination systems. Notably, WT1 also interacts with WTAP, a factor involved in m6A methylation of RNA, a mechanism that regulates sex determination in drosophila. Our preliminary results suggest that m6A methylation plays a key role in the sex differentiation of supporting cells. To address how this mechanism regulates sex determination, we will determine the kinetics of RNA methylation during gonadal development followed by a functional analysis using mouse models deficient in Wtap and Mettl3, the catalytic unit of m6A methylation. Using transcriptomic analysis of methylated RNA, we will determine how the male and female programs are affected by lack of m6A methylation. We will then use genetic engineering to prevent methylation of critical genes to demonstrate the role of this mechanism in regulating sex determination in mice. This work will reveal u
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Artificial Compartment for Coenzyme Regeneration' (ARC-for-CORE) targeting Horizon 2020.

assistant: **Abstract**

This project is to build an artificial compartment for coenzyme regeneration, urgently demanded by industry and scientific research to enhance the stoichiometric use of coenzyme in biosynthetic pathways. The fellow will investigate all-round aspects of the bio-inspired system, including compartmentalization process, mass transfer and biological reactivity. A new mechanism for selective bidirectional transport and structure-reinforced composite shell will be proposed. Capitalizing upon his expertise in biomimetic controlled delivery system, carbon nanomaterial, emulsion and scanning electrochemistry, the fellowship makes him a unique asset to EU for the brand-new exploration of bio-inspired selective transport system and coenzyme regeneration compartment. The fellow has proven track record with multi- and interdisciplinary background and his achievement has been outstanding as demonstrated in CV. The skills he will gain allow him to diversify his capability significantly, including interfacial polymerization and molecular imprinting technique, visualized delivery dynamics, capsule manipulation and stability test, enzymatic integrity and activity test, compartmentalized enzymatic reaction, microfluidic multiple emulsification and techniques for SECM set-ups and analysis. The output will be the knowledge obtained from the formation of the artificial compartment through bulk and microfluidic interfacial polymerization, the compartmentalized enzymatic reactions and new set-ups for SECM. In addition, the fellowship will allow him to transfer his existing knowledge and the one emerged from the research to the hosts and a variety of audience, via complementary activities. The effective and reliable coenzyme regeneration system will address the challenge of coenzyme utilization
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Antidepressant discontinuation during pregnancy and relapse risk in the perinatal period' to be submitted under Horizon 2020.

assistant: **Abstract**

Antidepressants are the mainstay of pharmacological treatment for depressive and anxiety disorders in the perinatal period, and up to one in ten pregnant women take them. Among these women, over 50% discontinue antidepressants during pregnancy due to fear of possible adverse fetal effects. However, discontinuation may increase the risk of relapse, which can also have profound negative impacts. Evidence on perinatal relapse risk following antidepressant discontinuation during pregnancy is sparse and limited to highly selected populations. Moreover, the only factors considered in studies so far have been simple demographics and clinical features, while genetic profiling is conspicuously absent.  The project aims to address knowledge gaps which urgently need to be understood in order for clinical care to provide personalized antidepressant treatment recommendations around pregnancy. This overarching objective will identify women at low or high relapse risk after discontinuing antidepressants during pregnancy and determine risk factors of relapse to enable personal risk estimates for the first time, in a large representative population, combining demographics, clinical features and genetic data retrieved from Danish national registers and the Integrative Psychiatric Research (iPSYCH) cohort. The project will provide a unique opportunity due to its multidisciplinary nature and innovative combinations of genetics and epidemiology. The proposed research will benefit from the expertise in genetics, genomics, and psychiatric epidemiology of the supervisors, and the fellow’s multidisciplinary skills in epidemiology and biostatistics applied on large, highly complicated datasets. The fellow will acquire state-of-the-art skills in the analysis of genetic data, planning, and managem
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Improving nutritional properties of foodproducts: development of novel technologies to yield fresh and processed products extracted from pomegranate fruits.', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

The pomegranate fruit possesses unique characteristics both of nutritional and medical value. Despite its many advantages, it is currently a minor crop with limited marketability. The major obstacles to the realisation of the full potential of this unique fruit are the difficulties in mechanically retrieving the internal edible seeds. The current crude manual process of extracting the seeds is laborious and costly, and discourages potential consumers from buying the fruit. It is aimed by this project to develop:- a mechanical system producing 500 kg/hour of clean and undamaged seeds. - a suitable Modified Atmosphere Packaging for the seeds, maintaining original quality for at least 6 weeks. and investigate:- the application of pomegranate seeds in different foodstuffs. To reach this goals it will be necessary to work on the following aspects:- automation and robotics for fruit sorting systems - investigation of the post-harvest physiology of pomegranates - identification of optimum package - study of the effect of inactivating the micro-organism and enzymes in pomegranate seeds - investigation of new approaches for utilising edible coatings
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The World’s First Browser-based and Automated High-end Virtual Reality Content Management System' (HEGIAS) under Horizon 2020.

assistant: **Objectives**

90% of all construction projects are subjected to budget overruns and time delays causing hundreds of billions of euros in annual losses, in fact, €472 billion was spent on construction errors in 2018. These continuous failures occur as direct result of workflow errors during constructions projects (miscommunication between stakeholders, long decision-making processes, misinterpretations of construction elements and insufficient colapse detection). Thus, AEC companies are seeking for a cost-effective, automated, collaborative and easy-to-use productivity-enhancing technology to optimize the projects lifecycle. This demand is boosting the growth of the High-end Virtual-Reality VR data visualisation (€131,1 billion as expected market value by 2021).We, at HEGIAS AG, are developing the world’s first browser-based and automated Virtual Reality Content Management System, HEGIAS VR, that will not only democratize Virtual Reality for the first time, but will also enhance available digital 3D-models (CAD, BIM) making them fully exploitable and collaborative with the aim to streamline the workflow of construction projects.We target private construction companies. We have successful implemented current HEGIAS VR version in 10 real-life projects with ground-breaking results establishing customer-relationships with leading Swiss companies. Outcomes from our real-life projects showed workflow optimization and decision-making process improvement by 90%, and cost reduction by 45%. HEGIAS VR not only creates added-value to our customers, but also to the citizens and the urban environment – real-time meetings at remote locations avoid extensive business travels, thus contributing to reduction of the carbon footprint.Through the completion of our project we expect to generate revenues of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Italian Women Writing Across Languages. Translingual Literature and Female Cosmopolitan Identities' to be submitted under Horizon Europe.

assistant: **Abstract**

TranslingWOL investigates the literary production of Italian women writers involved in long-lasting mobility abroad who express themselves in languages other than Italian, between the 19th and 21st centuries. From a transnational perspective, using an interdisciplinary set of methodological tools (literary theory and criticism, multilingual studies, women’s studies, sociology of literature, archival research, and digital humanities), it provides the first extensive academic study dedicated to Italian translingual women’s literature, which has been excluded from canonisation processes in both Italian and foreign literary histories, and largely overlooked by scholars, on account of its heterodox nature as compared to the traditional identity between language, literature, and nation.Through close-readings of representative case studies, the project shows the existence of common traits within this panorama – at the textual level (motives and forms) and the contextual level (publication and reception) – and leads to the creation of an interpretative framework useful for the study of such production, an alternative to post- and inter- colonial paradigms to which this and analogous translinguistic phenomena are not merely assimilable. Through a distant reading of the overall panorama, all bio-bibliographical traces of each writer are collected and inserted in a specifically designed database, in order to consolidate the importance of the corpus, geo-map the areas of distribution of texts, and highlight the networks between authors.The goal is not only to rediscover a neglected female literary corpus, but also to provide an innovative gendered and multilingual perspective to interrogate literature. In step with EU policies promoting gender equality and multilingualism, Translin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Vertical cavity laser technology for interconnection and access links' (VERTICAL).

assistant: **Concept**

Thanks to their intrinsic properties, Vertical Cavity Surface Emitting Lasers (VCSELs) have a wide variety of potential use and represent the new generation of laser sources for Tele or Data communication. The main objective of VERTICAL is to realise a Long Wavelength (LW) 1.3 / 1.55 um VCSELs operating CW at room temperature, through the optimisation of electrical, optical and thermal properties of the structure and to test them in a system environment.The project addresses a very important issue : to succeed in the realisation of a 1.3 / 1.55 um VCSEL operating in continuous mode at room temperature. The intrinsic properties of VCSELs lead to specific characteristics of these devices.The volume of the active layer is around 10 times lower than in edge-emitting lasers. A reduction in the power consumption is therefore expected as well as the possibility of operation over a wide range of temperature.The output beam has intrinsically low and circular divergence, unlike in edge-emitters which have fan-shaped highly divergent astigmatic beams. In consequence, efficient coupling and simplified pig-tailing will contribute to the increase of positioning tolerances. This advantage, combined with the on-wafer testing capability, are key factors towards a sharp cost reduction of modules, since testing, mounting and assembly time represent more than half the cost of an optical source.Expected ImpactAll the arguments developed in the previous paragraph make VCSELs very good candidates for low-cost system in the access area. Such applications, which are generally Short Haul trunks (10 - 20 km) do not require high output power at the emission side. This relaxed tolerance is very well adapted to the limited output power we can expect for long wavelength VCSELs (10 to 100uW for curren