RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Smart Textiles made from Agriculture and Natural Waste Materials' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

The main objective of the SMARTWASTE MSCA SE project is to form a world class international and inter-sectoral network of organizations, working on a joint research programme in the field of novel Sustainable Smart Textile Materials, by replacing conventional and high costs textile materials with sustainable, environmentally friendly, cheaper and novel materials such as cellulose fibres from tomato stems waste and creating nonwovens from unconventional poplar seed fibers. This can only be achieved by bringing together world-class experts in materials, polymers, environmentalists, chemists, software engineers, and designers with state-of-the-art innovations and processes in their respective fields of expertise. The participants will exchange skills and knowledge to create sustainable textile materials, strengthening collaborative research between different countries and sectors. SMARTWASTE will also refine and produce potential commercial market opportunities for non-academic participants in the project (WP7). Our goal is to train next generation of researchers and innovators in sustainable textiles through cross-sectoral and training modules. The staff members will develop new skills, be exposed to new research and innovation environments, international networks, new industrial processes and techniques whilst widening and enriching career development through cross-sectoral knowledge transfer and international mobility.


**Keywords:** tomato fibre, sustainability, metal coating, conductive textiles
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Biomedical Research and the Future of Property Rights', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

This research project investigates the dynamics of private and public property in contemporary biomedical research. It will develop an analytical framework combining insights from science and technology studies, economic sociology, and legal and political philosophy, and pursues a social scientific investigation of the evolution of intellectual property rights in three fields of bioscientific research: 1) the use of transgenic research mice; 2) the legal status of totipotent and pluripotent stem cell lines; and 3) modes of collaboration for research and development on neglected diseases. These three domains, and their attendant modes of appropriation, will be compared across three general research themes: a) the production of public scientific goods; b) categories of appropriation; and c) the moral economy of research. The project rests on close observation of research practices in these three domains. The BioProperty research programme will track the trajectories of property rights and property objects in each of the three fields of biomedical research.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Brainstem circuit ensembles for movement flexibility' in the context of a Horizon Europe call.

assistant: **Objectives**

Movement is the shared language of behavior across the animal kingdom, orchestrated by dedicated circuits throughout the central nervous system. To survive, animals must move with a high degree of flexibility, requiring precise and rapid changes in speed and trajectory. This flexibility of locomotion depends on the brain's ability to select appropriate motor programs and coordinate body and appendage muscles to match the locomotor movement parameters to the behavioral context. In particular, the brainstem has been identified as the major site for shaping motor commands to provide this flexibility. A key, unsolved question is how the final brainstem commands are generated and adjusted. In this project, we will test a new hypothesis that challenges current views in motor control, namely that the final motor commands driving the flexibility of locomotion movements are the combined product of precise interactions between circuit ensembles in the brainstem and real-time feedback from the spinal circuits. Our approach harnesses the powerful combination of all-optical techniques, scRNAseq, and electrophysiology at single-neuron resolution to determine the principles of circuit integration within and across brainstem circuits in adult zebrafish. This innovative approach will allow us to uncover circuit function, at a level of resolution that has never been achieved before, in a behaving vertebrate animal. By performing a system-wide analysis at single-cell resolution, we expect to gain unique insights that will transform existing views in the field of motor control. This project will chart a novel, system-wide circuit blueprint for movement control and flexibility in vertebrates.


**Keywords:** Brainstem, spinal cord, locomotion, motoneurons, motor control
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'A Cinematic Archive for the Future: Women's films in Italy 1965-2015' under Horizon 2020.

assistant: **Concept**

Despite rising institutional concern for the gender gap in the European job market in general (EU Gender Action Plan 2016-2020) and the film industry in particular, the Italian market share of films directed by women in the period 2006-2013 was 2.7%, while that by male directors was 97.3%. The Italian film industry is sealed shut even tighter for creators whose identities intersect womanhood with a non-white or migrant background. This action redresses the persistence of this staggering imbalance by addressing the near-absenting of women’s and accented voices, both in the discourse around and practice of Italian filmmaking. The aim is to provide a critical record of the contribution of women, and especially women of colour, in the period 1965-2015, as a tool for launching the rebirth of Italian cinema.  Research by the European Women’s Audiovisual network has found access to funding to be the most problematic aspect hindering gender equality in the Italian cinema sector. This 50-year period is marked by two crucial moments in the regulation of funding for audiovisual production in Italy (the 1965 “Legge Corona” and the most recent reform, voted into parliament in 2016). The project will accomplish two objectives at once: the obviation of encrusted film historiography canons, and the creation of an alternative archive of cinematic creativity with the capacity to reinvent the category of Italian cinema. Through the creation of an open-access collaborative online database, CineAF will provide a set of tools to create visibility and awareness of the gender inequality in the film industry; a change of script for the way we narrate Italian cinema to ourselves and to the world; and a roadmap for the innovation of the sector. CineAF will showcase the persistence of women's crea
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Female Prophecy in Early Modern European Religion', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

This project is the first attempt to create a theoretical account of female prophecy in sixteenth century Italy, Spain and England as a key to understanding crucial political concepts such as authority, discipline, spirituality, agency and expectation. It identifies sixteenth-century Italian ‘living saints’ and humanists; Spanish beatas and conversas; and English visionaries as privileged actors of prophetic charisma and challenges assumptions that prophecy responds just to national or local interests and debates. A transnational approach is needed to demonstrate the close parallels and exchanges in Italy, England and Spain in this era of extensive religious mobility. Without neglecting the differences, this project explores the circulation of female prophecy in Italy, England and Spain before the Universal Church was completely divided. The analysis will concentrate on a corpus of women prophets, i.e. the texts written by women prophets and their male counterparts (confessors, hagiographers and devotees), as well as by secular women (such as humanists) in order to identify interconnections and models of female prophecy in early modern religion. This corpus includes sermons, visions, spiritual letters and poems, hagiographies and inquisitorial trials. The project’s supervision by Unn Falkeid, historian of ideas at the University of Oslo, and by Nicholas Terpstra, social-cultural historian at the University of Toronto, as well as the excellent research environment of the host institutions, will ensure the project’s success. The University of Oslo hosts a growing research team on Renaissance and early modern women and religion, and so is the most fitting environment to carry out my project during the return phase. The University of Toronto (outgoing phase) is the perfect
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'MEET RESEARCHERS TONIGHT!' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

In the context of one of the most powerful and rich economic areas of Europe, Milan and Lombardy Region, MEETmeTONIGHT was born as an initiative of Politecnico di Milano together with the main city universities and for the first time is extended to the entire Regional territory. The project will involve 3 full partners and, as associated partners, a long and various list of public and private entities (all main Milan universities, Lombardy Region Government, Province of Milan, Municipality of Milan, foundations, associations and media partners).The concept of the overall project is to enhance the awareness among the citizens that universities, science and research represent nowadays the future of the whole society and its main actors, that is to say the Researchers, will impact with their job on competitiveness, economic growth, employment, environmental protection and in general on citizens’ daily life.Therefore it aims at: a) showing to common people the normality of the daily Researchers’ life; b) amplifying the social image of Researchers; c) opening up consciousness about the importance of a scientific career in the local, national and European context; d) launching the first Lombardy Researchers Night as a distinctive date to be attended every year, so to foster the liaison between Researchers and citizens.The practical aim of the project is to organise an outstanding evening where people will have the opportunity to meet and know the Researchers directly. MEETmeTONIGHT wants to communicate the message: “Researchers are people like you! Meet me and see what I do everyday”.The central locations of the event (in the Milan city centre) will encourage the involvement of a large number of people. Simultaneously  on all Lombardy campuses of the University partners and o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Regional turboprop loads control through active and passive technologies' (RELOAD).

assistant: **Concept**

A number of active and passive Loads Control and Alleviation concepts and technologies will be proposed, developed and evaluated. Aerodynamic design of an innovative spoiler will be undertaken, followed by a detailed aerodynamic characterisation of the spoiler and aileron capability for active loads control alleviation, conducted by means of CFD simulations and Wind Tunnel Tests. Novel passive loads alleviation concepts, such as passively morphing aerofoils using thickness and stiffness tailored skins or memory polymer skins and passively floating flaps, are going to be investigated and evaluated. A structural concept for an aeroelastic winglet for passive loads alleviation in manoeuvres and gusts will be developed.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'PalaeoEcology and OPen-LandscapE adaptations of Pleistocene humans in South Africa' under Horizon Europe.

assistant: **Concept**

Homo sapiens emerged in Africa in the Middle Pleistocene, and their appearance broadly overlaps with the onset of the Middle Stone Age (MSA). This period saw a persistent population expansion into a wide range of ecosystems, including deserts, rainforests, and mountains. To develop such ecological flexibility, early humans had to adapt their subsistence strategies to markedly different and dynamic environments that dramatically affected their lifeways. However, we know surprisingly little about the timing and modes of H. sapiens dispersal within Africa. To address this issue at subcontinental scale, PEOPLE will look at South African ecosystems that offer ways of assessing human response to climate change. One key factor affecting this response is freshwater availability. Water played a crucial role in human adaptation since it determined the foraging activities of people across the open landscape and thus had pervasive influence over their expansion on the continent. In the interior of South Africa, which features a mosaic of diverse grasslands and arid shrublands dissected by sporadic rivers, ancient water courses and wetlands provided early humans with favourable conditions and possible dispersal routes. To understand how and when humans settled on the subcontinent, PEOPLE will search geological deposits at rivers, springs, and dry lakes in the interior of South Africa, which offer long records of climate change. The aim is twofold: determine the role of changing environments in the adaptive strategies of MSA people, and establish a chronology for human palaeoecology based on absolute dating of palaeoenvironments and technological organisation. To achieve these goals, PEOPLE will adopt a multi-scalar geoarchaeological approach led by an interdisciplinary research team
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Complex analysis and statistical physics'.

assistant: **Objectives**

The goal of this project is to achieve breakthroughs in a few fundamental questions in 2D statistical physics, using techniques from complex analysis, probability, dynamical systems, geometric measure theory and theoretical physics.Over the last decade, we significantly expanded our understanding of 2D lattice models of statistical physics, their conformally invariant scaling limits and related random geometries. However, there seem to be serious obstacles, preventing further development and requiring novel ideas. We plan to attack those, in particular we intend to:(A) Describe new scaling limits by Schramm’s SLE curves and their generalizations,(B) Study discrete complex structures and use them to describe more 2D models,(C) Describe the scaling limits of random planar graphs by the Liouville Quantum Gravity,(D) Understand universality and lay framework for the Renormalization Group Formalism,(E) Go beyond the current setup of spin models and SLEs.These problems are known to be very difficult, but fundamental questions, which have the potential to lead to significant breakthroughs in our understanding of phase transitions, allowing for further progresses.  In resolving them, we plan to exploit interactions of different subjects, and recent advances are encouraging.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Applications of graph transformation' (APPLIGRAPH).

assistant: **Innovation**

The principal objective of this Working Group is to promote applied graph transformation as a rule-based framework for the specification and development of systems, languages, and tools and to improve the awareness of its industrial relevance.The aims of this Working Group are- to co-ordinate and promote research activities in applied graph transformation,- to improve the systematic exchange and dissemination of information on graph transformation and its applications,- to provide formal graph transformation methods and modelling tools supporting the software development process including visualisation, prototyping, and safety issues, and- to provide formal graph transformation methods and modelling tools supporting the specification and implementation of concurrent and distributed systems.By considering graph transformation as a formal approach to system development, three lines of research will be pursued:Language issues. Investigation of features in graph transformation based languages, like typing, modularity, refinement, parallelism, concurrency, distribution, optimisation, and correctness.Tool issues. Conception and design of support tools for graph transformation based languages including editors, parsers, interpreters, compilers, optimisers, verifiers, and graphical user interfaces.Application domains. Demonstration of the usefulness of graph transformation by case studies in various areas like definition of visual languages, database models, concurrent and distributed systems, software process modelling, implementation of programming languages.Among the main activities, the Working Group will organise workshops and meetings and will disseminate information on applied graph transformation by publishing proceedings and handbooks. The goal is to enhance the visibi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Selective Inhibition of NOTCH by novel γ-Secretase Inhibitors in Tumours' under Horizon 2020.

assistant: **Concept**

Cancer remains one of the deadliest diseases and most deaths are due to treatment failure and metastasis. Tumor resistance and patient outcome are strongly associated with tumor heterogeneity, which is promoted by the self-renewing and multipotent cancer stem cells (CSC) and by limitations in oxygen availability generating hypoxic areas within the tumor microenvironment. The NOTCH signaling pathway is one CSC pathways frequently deregulated in human cancers but also essential in many normal tissues. Given the widespread involvement in human cancers, many attempts have been made to target NOTCH (e.g. γ-secretase inhibitors, GSIs) and the hypoxic regions in the tumor (e.g. hypoxia-activated prodrugs, HAPs) in patients. However, to date, GSIs and HAPs have not been successful in clinical studies due to limited anti-tumor responses and dose-limiting side-effects in healthy tissues. As part of the ERC project DIRECT, I have leveraged our newfound knowledge on NOTCH signaling and hypoxia in tumors to develop two classes of novel NOTCH /g-secretase inhibitors (GSI) that enable tumor cell-specific inactivation of the NOTCH pathway (PSEN2-inhibitor) or by generating a dual-specificity NOTCH-inhibitor that is only released and active in hypoxic tumor regions (HyGSI) without affecting normal tissues. This ERC PoC INGSIGHT will assess the technical and commercial feasibility of these two novel inhibitors of the NOTCH pathway with the potential to radically improve cancer therapy outcomes. We will demonstrate the maximum tolerated dose in normal tissues and the therapeutic effects using five different tumor models. We will solidify our IP position and we will conduct a market, competitor, and stakeholder analysis to ensure the selection of the most optimal business strategy. As a re