RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'IMPLEMENTATION OF ADVANCED AIRPORT APPROACH PROCEDURES INCLUDING VALIDATION AND ELABORATION' under Fifth Framework.

assistant: **Concept**

The IMPROVE project aims to enable the implementation across Europe of a set of advanced airport approach procedures. This main objective is supported by the following sub-objectives: Identify sets of mature airport approach procedures for implementation that have never been implemented; Elaborate the design criteria needed to create the airport approach procedures; Elaborate specific approach procedures for each one the three airports included in the proposal; Assess -using fast and real time simulation tools - the expected benefits of the proposed airport approach procedures; Assess the safety of the proposed airport approach procedures; Assess the operational aspects of the proposed airport approach procedures -though the use of real time simulation -; Perform a set of flight trials to prove the airworthiness of the procedures and to assess their benefits.This thematic network will provide a focal point for co-ordination and dissemination of results from the various research initiatives directed towards improving the efficient management and utilisation of railway infrastructure. By facilitating a concerted approach to research and exploitation of results the network will ensure that all stakeholders are encouraged to participate and potentially provide a critical mass to dirve further research and implementation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'FAM process improvement experiment' (FAMPIX), addressing dissemination and exploitation.

assistant: **Impact**

Like many small software firms in Europe, FEGS faces the challenge of remaining competitive in a business environment where the competitors are much larger companies with far greater resources. The FAMPIX experiment aims to offset this lack of resources by - focusing the software development process on market requirements, - increasing the functional content productivity of the development cycle, - establishing customer oriented, quality procedures and project management,- introducing improved systems for management information and dissemination,- stimulating a more quality-conscious culture within the company.THE EXPERIMENTThe effectiveness of the software development process will be improved as described above by concentrating on four areas:1. Information systems : create on-line access, with configuration management, to all required information; use FrameMaker as technical authoring tool.2. Quality and organisation : improve QA and operational procedures used in the software development process, and derive better project management methods.3. CASE tools : update development environment and provide a good set of tools, determine new company standards in each programming language.4. Training and dissemination : to bring improved methods into the company and engender a cultural change.Productivity will be increased and the new working procedures promoted by means of a training programme and a company intranet" making information easily navigable by hypertext. This information will include the revised QA manual. The baseline project is a single development cycle for FAM, a Field Analysis Modeller which is the main product marketed by FEGS, and which is upgraded and extended each year. The company has 21 employees of whom all are involved in some way in the baseline proje
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'environmentAL Toxicity chEmical mixtuRes through aN innovative platform based on aged cardiac tissue model' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

ALTERNATIVE will develop an innovative platform able to detect the cardiotoxicity of chemicals and their bio-transformation products. The novel platform will enable regulators and industry to identify, quantify and prevent cardiotoxic co-exposures to industrial chemicals and pharmaceuticals in a cost-effective way. ALTERNATIVE will particularly focus on cardiotoxic effects on older people, which is of high relevance in view of the ageing EU population and the high spread of cardiovascular diseases.The platform will consist of a three-dimensional tissue engineering in-vitro model mimicking the human cardiac tissue, coupled with a reliable, high-throughput monitoring system based on multi-omics analyses, and integrated into a Machine Learning (ML) risk assessment tool. In addition, ALTERNATIVE will modify the tissue model to reproduce the aged myocardial tissue and elucidate the adverse effects of chemicals on older people. ALTERNATIVE?s proof-of-concept validation will be performed on well-known mixtures of pollutants, affecting different environmental compartments, and selected via epidemiological, toxicological and modelling expertise.ALTERNATIVE will also provide systematic reviews of high-quality epidemiological studies to support integrated in vitro and in silico data, giving a more robust basis for regulatory decisions.The ALTERNATIVE platform will be an innovative tool for complying with the current regulation associated with the assessment of chemical compounds. It will be a new instrument to evaluate unpredictable toxicity due to synergistic effects of different chemicals, additionally worsened by the human ageing process.By introducing an in vitro cardiac system and ML models, ALTERNATIVE will provide a platform able to refine, reduce and replace the need for a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Programmable Atomic Large-scale Quantum Simulation 2 - SGA1' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

The project Programmable Atomic Large-scale Quantum Simulation (PASQuanS2.1) is the first decisive step toward the transformation of the European landscape for programmable quantum simulators, finally delivering internationally leading platforms involving over 1000 neutral atoms in optical tweezer arrays and also in optical lattices. In the context of this Specific Grant Agreement, we will bring together partners from academia and industry (including technology enablers, platform developers, and end-users) to address central technological challenges. We will connect technologies across national borders and use our combined expertise and technologies to scale up the system size, reduce noise and temperature, and improve stability. We will test and transfer know-how between trapped ion and neutral atom platforms and integrate the hardware with application-specific software stacks for analogue solutions of relevant real-world problems, including verification and optimal control techniques. We will facilitate the expansion and networking of the supply chain and startup companies delivering platforms, en-route to the delivery of technology readiness level (TRL) 6-7 quantum simulators, including both cloud-based platforms, and quantum simulators linked with existing high-performance computing infrastructure. We will work with the end-user community across academia and industry to identify new specific applications where quantum simulators provide a practical quantum advantage over traditional high-performance computing. We will particularly address potential applications in materials science, quantum chemistry and in optimisation. We deliver a clear plan for dissemination, exploitation, and communication. This includes developing and protecting intellectual property, and to e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Role of Epoxyeicosatrienoic Acids in the Regulation of Blood Pressure, Renal Hemodynamics and Sodium Excretion in Renovascular Model of Hypertension' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

Cytochrome P450 (CYP) metabolites are more frequently recognized as important regulators of cardiovascular and renal functions. CYP epoxygenases produce epoxyeicosatrienoic acids (EETs) that exhibit vasodilatory and natriuretic properties. EETs are degraded by the enzyme soluble epoxide hydrolase (sEH). Inhibition of sEH increases the level of EETs and attenuates blood pressure (BP) and end organ damage in several models of hypertension. We would like to define the role of EETs in BP regulation in the model of renovascular two kidney one clip (2K1C) hypertension. We will examine whether sEH inhibition attenuates BP and improves renal autoregulation and pressure natriuresis in 2K1C hypertension. In addition, we will study the signaling of EETs in isolated renal arterioles to determine the changes in EETs - mediated signal transduction in hypertension. Overall, these studies could elucidate the role of EETs in the regulation of renal functions and BP under physiological conditions and in hypertension. In addition, these studies could provide new evidence supporting the role of sEH inhibitor as the new candidate for antihypertensive therapy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'The here and the hereafter in Islamic traditions'.

assistant: **Concept**

The aim of this project is to write a history of the Muslim paradise and hell. Researchers (PI, RF and two doctoral researchers) will assess the extent to which Islamic traditions favour or reject a view of human existence as directed toward the otherworld. They will do so by examining a variety of intellectual traditions from the inception of Islam in the 7th century CE until today. The focus of investigation will not just be on the ‘high tradition’ of Islamic theology and jurisprudence, but also on mystical, philosophical, artistic and ‘popular’ traditions, thereby avoiding a monolithic, essentialising account of Islam’s attitude toward the hereafter.As has been argued, the relationship between this world (dunya) and the otherworld (akhira) is as important to Islam as the mind/body dualism is to the intellectual history of the West. However, no sustained effort of analysis has been made in modern Islamic Studies to reflect on the dunya/akhira relationship, and on the boundary that separates the two. This project will be the first comprehensive and systematic attempt in this direction. Five axes of research will underlie this endeavor: (1) the eschatological imaginaire, (2) material culture and the arts, (3) theology and law, (4) mysticism and philosophy, and (5) modern and contemporary visions of the hereafter.The project (proposed duration: 48 months), which is to begin on 1 March 2011, will be based at the Utrecht University and led by Dr Christian Lange (PhD Harvard, 2006, 70%), currently Lecturer in Islamic Studies at New College/School of Divinity. The research team will include one research assistant (100%, 45 months) and two doctoral researchers (100%, 36 months). Financial support is solicited to facilitate the survey of manuscripts and manuscript research in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'New concept for classical vertical pianos conclave' (1994-1998) under Fourth Framework.

assistant: **Objectives**

This proposal was presented earlier and evaluated under the number BEST-2847. In the following the proposal has been revised according to the given remarks and recommendations of the experts. The branch of Europe's manufactures of classic pianos consists of SME's exclusively and they are rather traditionally orientated enterprises. The production of these musical instruments is determined mainly by handicraft. These companies and their suppliers have to compete on one hand with products industrial made in the far east in great numbers by large groups like e.g. YAMAHA. On the other hand the market is going to be submerged with electronic instruments mainly also produced in tiger states. The characteristic and main shortcoming of the electronic instruments is the artificial generation of the tone. The way of playing can not be compared to classical instruments. The comprehensive history of European music was nevertheless written for classical instruments. The chance of European producer of pianos to overcome this jeopardy lies in a concentration on their specific knowledge. A piano produced with the use of innovative technologies and an instrument which represent an attractive piece of furniture. For the success of this concept a flexible and qualified structure is useful. Therefore a closer cooperation of the European producers is aimed also.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Reliable AI and Data Optimisation'.

assistant: **Objectives**

RAIDO is a powerful framework solution designed to develop trustworthy and green artificial intelligence (AI). Trustworthy AI focuses on ensuring the reliability, safety, and unbiased optimization and deployment of AI systems, particularly in critical applications such as healthcare, farming, energy, and robotics. On the other hand, Green AI involves the development and deployment of energy-efficient and environmentally sustainable AI technologies, leading to reduced environmental impact and improved resource management.RAIDO provides an array of automated data curation and enrichment methods, including digital twins and diffusion models, to create high-quality, representative, unbiased, and compliant training data. It also offers various data- and compute-efficient models and tools to create energy-efficient Green AI, such as few- and zero-shot learning, dataset and model search, data and model distillation, and continual learning.To ensure the transparency, explainability, and reliability of the optimized AI models and data handling processes, RAIDO uses various XAI methods, decentralized blockchain, feedback-based reinforcement learning, novel KPIs, and visualization techniques. Additionally, the innovative AI orchestrator optimizes related tasks and processes, reducing the overall energy consumption and environmental footprint of the models during both development and deployment.RAIDO emphasizes the development of dynamic interfaces that support the appropriate AI paradigms (central, distributed, dynamic, hybrid) and enable seamless adaptation to the needs of the use situation. Furthermore, RAIDO will be evaluated through four real-life demonstrators in key application domains, such as smart grids, computer vision-based smart farming, healthcare, and robotics, showc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'HEPATIC MICROFLUIDIC BIOREACTOR' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The goal of HeMiBio is to develop a hepatic microfluidic bioreactor from human iPSC-derived hepatocytes, hepatic sinusoidal endothelial cells (HSEC) and stellate cells (HSC), suitable for inclusion in a repeated dose toxicity testing strategy of pharmaceuticals/cosmetic ingredients. The successful creation of such a liver-device requires (a) homotypic and heterotypic interactions between the three cell types to induce and maintain their functional, differentiated state, and  (b) optimisation of the matrix, oxygenation conditions, nutrient transport and physiological shear forces. The objectives are (1) to engineer the cellular components incorporated in the bioreactor to enable specific and spatially defined enrichment of the different cells from iPSC progeny, and, by gene editing, to allow non-invasive monitoring of the cellular state (differentiation and damage). (2) Aside from the molecular sensors, an array of electro-chemical sensors will be embedded in the reactors to assess liver-specific function and cellular health under repeated dose toxicity conditions, dynamically and in a high-throughput way. Cells and sensors will be built into (3) bioreactors that will be sequentially upgraded from 2D to 3D microfluidic reactors to ultimately allow full maintenance of mature functional hepatocytes, HSC and HSEC for >28 days.  (4) As the ultimate goal is to use the device as a human-based alternative to rodent long-term hepatotoxicity studies, it will be of utmost importance to provide proof of concept that the 3D-devices reveal the hepatotoxicity of prototypical hepatotoxic compounds in vivo (5). “-Omics” and cell functionality studies will provide evidence that liver-like cells are present, exposed and affected by the selected toxic compounds. These ambitious objectives
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Trading Platform for Sustainable Carbon Credits' (CARBOMART) targeting Horizon 2020.

assistant: **Abstract**

CARBOMART project is a sustainability comparison tool to create an online carbon trading platform, which allows the carbon credit buyers to evaluate the carbon emission reduction projects according to the social, environmental and economic sustainability criteria. The CARBOMART proposes solutions for the Voluntary Emission Reduction Market, which is an incentive mechanism for disseminating the investments on climate friendly low carbon energy projects.Therefore the outcome of this project will facilitate;-Low-cost, low-carbon electricity supply-Reducing Greenhouse  Gas emissions due to energy consumption-Increase in the forested lands (carbon storage)in a sustainable wayby increasing the income of the renewable energy, energy efficiency and afforestation projects.General objectives Green Consult and Finance (GCF) targets through CARBOMART are;•Developing a reliable sustainability comparison tool for the voluntary emission reduction projects,•Developing a measurable pricing methodology for the Voluntary Carbon Market •Creating an accessible platform for both buyers and sellersIn line with these objectives the expected impacts are;•Facilitating the transparency voluntary carbon market.•Increase in the quality of voluntary emission reduction projects in terms of sustainability,•Increase the investment made in carbon emission reduction projects so that decrease the emission reductions up to 5%, since the effects of the carbon credit income to the IRR of an green energy investment is around 5%.The market volume is expected to be 4.1 billion USD by 2020. It is planned that the CARBOMART would be fully commercialized by 2019 and reach a sales income of 20 million Euros by 2023. To ensure a successful entrance and fast penetration into the European markets, the outcomes of the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Cis-regulatory variation: Using natural genetic variation to dissect cis-regulatory control of embryonic development.' (CISREGVAR).

assistant: **Innovation**

Embryonic development is very robust: In the midst of segregating mutations and fluctuating environments, a fertilized egg has the remarkable capacity to give rise to a precisely patterned embryo. The stereotypic progression of development is driven by tightly regulated programs of gene expression. However, this deterministic view from genetics is at odds with an emerging view of transcription from genomics as a “noisy” process, variable and changing both within and between individuals. How variable transcriptional programs can regulate robust embryonic development remains a long-standing question, which this proposal aims to address. By combining population genetics, genomics, and developmental genetics in Drosophila we will dissect the relationship between DNA sequence variation, transcription factor (TF) occupancy, and the regulatory control of developmental gene expression.The backdrop for this work is extensive information generated by my lab on the location and function of over 12,000 developmental cis-regulatory elements, including accurate, predictive models of their spatio-temporal activity. To understand the impact of variation on transcription and development, we will make use of a powerful experimental resource – 192 sequenced Drosophila strains, collected from a highly genetically diverse wild population. The proposed research has three Specific Aims:   1) Perform the first high-resolution study associating SNPs and structural variants (eQTLs) with gene expression variation during embryonic development, 2) Quantify in vivo the relationship between cis-regulatory variation, TF occupancy, and gene expression, 3) Incorporate these data into an integrated, predictive model of transcription. These Aims, together with our cis-regulatory data, will offer unique, m