RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Groundwater risk assessment at contaminated sites' in the context of a Fifth Framework call.

assistant: **Objectives**

Problems to be solvedContaminated land in Europe poses a serious problem with respect to soil quality and the risk of spreading of pollutants into other compartments of the environment. The major concern at most contaminated sites is the risk of groundwater pollution by organic and inorganic compounds. Since, the remediation of all of the contaminated sites in Europe is economically not feasible, groundwater risk assessment procedures are needed for the ranking of sites, decision making on further use and remedial actions. In contrast to existing procedures this project concentrates on the development of methodologies for the assessment of the mobile contaminant fraction in contaminated soil and waste material. (i.e. the contaminant fraction that would reach the aquifer). It will allow the determination of the long-term contaminant release rates and the overall emission of pollutants into the groundwater at contaminated sites. The most important innovations expected will be more harmonized and integrated guidelines for groundwater risk assessment in Europe and beyond.Scientific objectives and approachThe procedures to be developed take the form of a scenario approach, as it is intended to be generally applicable to different situations in terms of classes/combination of pollutants and site-specific conditions, such as climatic conditions, permeability and distance between contamination and groundwater table. Such a scenario approach will allow the determination a priori whether; under given site conditions (subsurface permeability, distance to groundwater table, type of material) and contaminant properties (volatile / non-volatile / water soluble etc.), a minor, medium or high risk of groundwater pollution exists. The validation of these new risk assessment procedures w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Microfabricated hydrogel-based complex patch with time dependent controlled multiple-release of biomolecules for improved healing of skin wounds' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Skin wounds represent a significant economic and social burden, associated with a long-lasting nature and need of care. Most of the commercially available patches for wound healing have been proved very useful in wound management but are yet to demonstrate a direct effect on the progression of the healing. This has significant implications in the quality of the clinical results obtained so far. Skin patches can be substantially improved in terms of the healing time, with clear benefits in the patient’s quality of life and in reducing health care systems costs, as well as on the quality of the new skin. The use of hydrogel-based patches has clear advantages in maintaining the moist environment required for improved healing but those devices are not yet designed to actively aid the healing process. Because the healing cascade is a complex and step wise process, PATCHED proposes to proof the feasibility and efficacy of a hydrogel-based patch designed to address that complexity and time dependence. PATCHED relies on the versatility of a technology developed under the scope of ComplexiTE ERC AdG that will allow extending its outputs towards a concurrent biomedical application. Therefore PATCHED will produce a prototype of an innovative multi-component hydrogel-based patch that contains selected biomolecules that will have different actions according to different microenvironments of the wound. By tailoring the composition, size and shape of the components, a time-dependent release of the biomolecules will be achieved according to the different healing microenvironments. This should result in a dynamic and cooperative effect that will address the complexity of the wound process resulting in improved healing. Overall PATCHED represents the proof of concept of a commercializati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Single molecule reconstruction for high-throughput, short-read sequencing technologies' (FuseSeq).

assistant: **Innovation**

Current advanced short-read sequencing technologies and third generation long-read sequencing technologies are still not capable of full molecule reconstruction in a high throughput manner due to their limited read length and throughput respectively.This project aims at bridging the gap between long reads and high throughput by developing a fragment labelling system compatible to high-throughput short-read Illumina sequencing technology. The labelling system consist of tags that can be incorporated into the target nucleic acid sequences using Tn5-transposase and can be subsequently used to create fragments from the target molecule, allowing the generated fragments to retain information of their original position in the target molecule, thus the reconstruction of the sequence of the original, individual target molecules from them.This technology has considerable market potential due to its relatively high ease of market entry as it can be incorporated in existing library preparation techniques for next generation sequencing since many of them readily use Tn5 transposase for fragment generation. Additionally, the ability to be able to link the short, high accuracy reads generated by high throughput next generation sequencing technologies can have a large interest in the field of genomics, by allowing the complete reconstruction of diploid human genomes by tackling more difficult, highly repetitive genomic segments, in the field metagenomics, by enabling the assembly of more complete genomes from clinical samples, and also in the field of transcriptomics, by providing information about isoform- and allelic-specific expression through the reconstruction of full length transcripts.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Automatic Decision making and JUSTice: artificial intelligence, court actors and the right to a fair trial' (ADJUST).

assistant: **Concept**

ADJUST investigaADJUST investigates the integration of Artificial Intelligence (AI) and Automated Decision-Making (ADM) in judicial systems, focusing on their impact on fair trials. There are almost 100 such systems in use in Europe alone, conducting tasks from menial transcriptions to complex matters such as suggesting relevant precedent or estimating the risk of recidivism. While AI promises to enhance the efficiency and coherence of adjudication, its use also raises concerns about bias, transparency, and the potential erosion of judicial discretion. Much existing research overlooks either the specific training and design of each system, or the role of court actors beyond judges, such as clerks and registrars, who interact directly with the systems and whose tasks are prone to automation. Overlooking these two dimensions risks oversimplifying the analysis of AI’s benefits and drawbacks. ADJUST fills this gap by pursuing three objectives: 1) Mapping existing ADM applied in courts, 2) Investigating why court actors do or do not trust and implement ADM, and 3) Understanding how ADM technology impacts the right to a fair trial.The project employs an interdisciplinary approach, bridging human rights law and computer science. It does so by 1) mapping existing ADM applied in courts worldwide, and 2) conducting an in-depth comparative study of three legal systems: the European Court of Human Rights, and two Danish and two Italian courts. These case-studies are selected for their heterogeneity in legal systems and adjudicative procedure, use of precedent, and division of labour between court staff.My publication record on AI, courts and judicial discretion, my current involvement in a technical Horizon project developing human right compliant AI, as well as the leading role of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Platform for European CMOS Imagers - EUROCIS' under Seventh Framework.

assistant: **Concept**

The main goal of this project is the creation of a European supply chain for state-of-the art CMOS imagers.  As identified by both ESA and the EC, there is a need for such a supply chain for CMOS imagers for space applications which uses solely European (and hence ITAR-free) sources. This goal will be realized using the proposed consortium as all partners have excellent know-how and track record in the expertise fields required.A second goal of the project is to push the performance of CMOS imagers and match the requirements for the (typically very demanding) space applications.  Hence large area (much larger than commercial imagers) high sensitivity imagers will be developed using stitching technology and backside thinning.  A key element here is the backside passivation process using laser annealing.The outcome of this project is a CMOS imager design and manufacturing platform that can be used by the space industry (ESA, CNES, satellite manufacturers, ... ) for their future space imager needs.  However, it will as well serve (and will be open for) other high-end imager needs in e.g. medical or security applications.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'European Molecular Biology Laboratory, Hamburg Outstation' (1994-1998) under Fourth Framework.

assistant: **Objectives**

Principal characteristics of the facility and of the support offered to users: The EMBL Hamburg Outstation is situated at the DESY site and is provided with synchrotron radiation (SR) from the DORIS storage ring of DESY. The Hamburg Outstation has research interests in molecular structural biology, using synchrotron radiation. It operates seven SR beam lines available to external users: four for protein crystallography, two for small angle scattering from non-crystalline systems and one for X ray absorption spectroscopy. These beam lines have been built and are maintained by the EMBL Hamburg Outstation. SR is currently available for 31 weeks per year, of which on average 150 days per beam line are offered to external research groups. The projects of external research groups are selected and scheduled according to peer review results from an international Priorities Committee. Each external project is supervised by a staff member of the EMBL Hamburg Outstation. The Outstation provides ancillary equipment and its scientific infrastructure to external users to obtain optimal experimental results, but it cannot offer travel and subsistence support for external users. The Outstation is visited by about 500 external users per year from most of the European countries, in part supported by the current HCM contract (CHGE-CT93-0040). The beam lines of the Hamburg Outstation are recognised as leading and unique facilities in Europe. Under this proposal, the Outstation's scientific experience and infrastructure, centred on its beam lines, is offered for training in the structural biology methods applied at the Hamburg Outstation, thereby increasing the mobility of new European scientists from countries where comparable facilities do not exist. Quantity of access being offered and n
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Elucidating novel post-transcriptional regulatory mechanisms in neural development' under Horizon 2020.

assistant: **Concept**

During brain development, neural stem cells (neuroblasts) divide asymmetrically to produce a neuroblast and a neural progenitor cell, the ganglion mother cell (GMC), which will later divide to produce two neurons or glia. Asymmetric protein localization and transcriptional activation are two well-established mechanisms that influence cell fate decisions during this process. I hypothesize that a relatively unexplored regulatory component—mRNA stability—also plays a major role in neural differentiation. mRNA stability is regulated to achieve high temporal and spatial control of gene expression and may therefore provide a powerful way to establish or reinforce cell fate decisions in the nervous system. However, little is known about the functions of regulated mRNA stabilization or decay during development of the brain (or any other complex tissue). Our lab recently discovered that the mRNA encoding a key conserved neural differentiation-promoting transcription factor, Prospero, is unstable in Drosophila neuroblasts, but is stabilized in the more differentiated GMCs. This proposal seeks to expand upon this finding and to determine the extent of mRNA stability regulation and its functional significance in the developing brain. I aim to develop a novel genome-wide technique that will allow quantitative comparison of mRNA decay rates between neuroblasts and GMCs. I will then use this technique to query the function of conserved RNA-binding proteins in the regulation of neural mRNA stability. Finally, I will use our state-of-the-art live brain imaging assays to determine the functional requirement for specific regulatory events in brain development at the cellular and molecular levels. The experiments described in this proposal have the potential to uncover a major new class of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Photo-switchable ultra-thin membranes for molecular separation' to be submitted under Horizon Europe.

assistant: **Abstract**

The separation of molecules and ions by membranes is essential for the separation of gases, purification of water, energy conversion and storage, and many other applications, and is therefore of crucial technological importance for achieving the sustainable development goals ""clean water and sanitation"", ""affordable and clean energy"", and ""climate action"" defined by the UN. The membranes established to date suffer either from a poor compromise between permeability and selectivity or from fouling. Innovative concepts to extend the lifetime of membranes and to improve their separation performance are urgently needed to achieve the aforementioned goals as quickly as possible.PhotoBrane will train a new generation of leading experts in a completely new approach to membrane technology to take separation performance and longevity to a new level. Our research will be built on the most modern membrane materials, investigated by PhotoBrane’s PIs. In our new research approach, we are exploring how to use photochemistry methods to develop photo-switching regimes of the membrane’s wettability to prevent their fouling. To achieve unprecedented separation performance, we take the photo-switching a step further and investigate the influence of photo-tuning the structure, porosity, and polarity of dye-loaded membranes on their function in gaseous and liquid media. Through this research, the doctoral researchers receive interdisciplinary training and, through secondments to industrial partners, gain insights into various topics of photo- and material chemistry as well as membrane technology. The excellent research is carried out at renowned European centers of membrane research and photochemistry. The mobility within the network, combined with excellent research and training, crea
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Commoning Education: Lessons from Latin American Popular Education in Buenos Aires – Argentina' (EduCommon), addressing dissemination and exploitation.

assistant: **Impact**

Democratic education is a condition for the construction and preservation of democracies. On this basis, UNESCO purposed in 2015 to rethink education as a common good to reverse the privatised views of education, dominant since the 1990s, which diluted the key role of education in the construction of democratic citizenship. This interdisciplinary action aims to reinforce a conception of education as a common good by foregrounding experiences that stretch beyond the traditional school model and actively engage civil society actors in an education for transformation and social justice. To this end, EduCommon will develop knowledge exchange through an intercultural dialogue between two educational/social trends recently developed in crises contexts: Commons Paradigm (CP) and Popular Education (PE). CP has gained strength in Europe after the 2008 crisis in several social domains, including education; however, so far has not provided relevant applications in education. PE is a long tradition in Latin America that offers numerous experiences organising education as a common good, as show the current projects in Buenos Aires emerged after the 2001 crisis. Although PE experiences have not been connected to CP and had barely gained visibility in Europe, they  both share key points with CP; both are based on the premise that an education for democracy must be democratically organised, and therefore promote the active participation of civil society through grassroot democracy and participatory citizenship models. Thus, EduCommon would bring out mutual synergies: CP would strengthen the theoretical framework of PE, whilst PE would provide CP with experiences to follow. To set up this intercultural dialogue, the fellow will bring to Argentina her previous knowledge on CP, whilst wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Upward Social Mobility under Socialism in Eastern Europe 1945-1989' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

CLASS-UP proposes a qualitative comparative study of upward mobility (UM) under socialism, comparing Poland, Romania, and Yugoslavia. UM was a crucial social battleground in postwar Europe. Yet, we don’t understand how UM worked in socialist states, which differed from the West because of the historical post-feudal and post-imperial trajectory, the upheaval of WWII, and the geopolitical changes after 1945. The latter resulted in a dramatic redistribution of welfare and socialist visions of UM which promised the collective advancement of the working classes and a new egalitarian society.First, (RQ1) how was UM defined, and what were its indicators? How was it presented in official discourses and the press, and how did these shape people’s horizons of expectations? CLASS-UP traces diverse layers of social reality to propose a socialist understanding of UM. It also critically revises sociological research from the period, which diagnosed and defined UM. After building context and a localized understanding of UM, CLASS-UP examines (RQ2) how UM shaped biographies and family histories. An innovative method of intergenerational class biographies follows advancing citizens and traces transfers of social, cultural, economic, and political privileges, along with the costs of mobility over generations. While new divisions based on welfare stratification, politics, and education shaped postwar socialist societies, persistent prewar distinctions remained: advancement and reproduction collided. Sensitive to gender, rural-urban divide, and ethnic diversity, CLASS-UP also includes provincial socialism, moving beyond the industrial hubs and cities. It reexamines postwar history focusing on those who experienced UM thanks to authoritarian regimes. With most of today’s population coming f