RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Advanced Dynamic Validations using Integrated Simulation and Experimentation' (ADVISE) under Seventh Framework.

assistant: **Objectives**

ADVISE is a prenormative project for experimental validation of simulations of dynamic events using full-field optical methods of deformation measurement. These powerful tools are used in evaluating the performance, reliability, and safety of primary structures and for validating their computational design.   Optimised design of primary structures leads to lighter and more energy efficient products that cost less, are more reliable and safer. Whilst in engineering modelling the analysis of homogeneous materials subject to impact has become fairly routine, recent advances have been made in modelling the impact of two-dimensional composites.  ADVISE brings together advances in optical techniques with the developments in modelling composites in order to establish high levels of confidence through rigorous validation.  Such an approach would represent a step change in the subject.   The innovative aspects and objectives of the project are: • development of reference materials that allow traceability and calibration of full-field optical methods of deformation measurement in cyclic, transient and non-linear dynamic events; • optimisation of methodologies for both optical measurement and computational modelling and simulation of non-linear, transient dynamic events; • contributions to standardisation activity for experimental validation of dynamic simulations. This represents the first attempt to provide a unified approach to experimental validation of engineering simulations of primary structures subject to dynamic processes, the development of reference materials for optical dynamic deformation measurement. The major contribution to standardisation through VAMAS TWA 26 ensures that the reference materials can become quickly accepted globally, thus providing worldwide tracea
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Determination of the absorption and metabolism of dietary flavonoids using human cell models.' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Measuring the rates of absorption of purified dietary flavorous (common glycosides and newly isolated structurally novel flavorous) and their subsequent metabolism using human cell models. In addition their effects on cell growth and viability will be measured using standard assays.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Vibrating microengines for power generation and microsystems actuation'.

assistant: **Concept**

The goal of VIMPA is to develop a new class of high energy and high power density generators to be embedded in portable or autonomous devices. The addressed domain is the one of Power MEMS, i.e. Micro Electro-Mechanical Systems able to exploit combustion f or mechanical and electrical power generation. Output densities are projected to reach many W/cc for power, while energy densities up to many KJ/cc are expected: both values are several times higher than the respective upper values of traditional batteries . Few attempts have been and are being conducted worldwide (mainly in the USA and in Japan) in the field, but no usable products have been developed, despite the strong need for miniature high performance power supplies and in spite of dedicated research programs and funding. The main reason of this delay is the adopted approach which consists of scaling down traditional engines, by developing micro turbomachinery or microengines inspired by already existing concepts. VIMPA aims at introducing a discontin uity in the Power MEMS technology by developing vibrating frictionless structures associated with repeated combustions. The first core idea is to focus on positive displacement machines instead of turbomachinery, where dissipation due to drag forces causes large inefficiencies in the micro domain. The second paradigm is to avoid any rotary or sliding joint in the engine mechanism, thus reducing friction, and to use elastic storing of energy instead of inertial, flywheels-like means, which become ineffective when scaling down machine's size. The enabling paradigm for the success of VIMPA is a real multidisciplinary consortium in which state of the art teams in combustion research, microengineering design and MEMS fabrication are included. VIMPA's goal will a llow EU
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'System for Environmental and Agricultural Modelling; Linking European Science and Society' (SEAMLESS) under Sixth Framework.

assistant: **Objectives**

The project will develop an integrated framework (SEAMLESS-IF) which integrates approaches from economic, environmental and social sciences to enable assessment of the impact of policy and behavioural changes and innovations in agriculture and agroforestry. Contributions of agriculture to sustainable development and multifunctionality will be assessed at different spatial scales from farm to global, allowing consideration of both top-down and bottom-up approaches to land management change. Innovative software architecture will be used to facilitate the use of quantitative biophysical and economic models and databases in combination, and to ensure re-usability of these tools well beyond the lifetime of the project. Indicators will be operationalised to communicate key information to users and between scales or disciplines, and methods for establishing threshold values for these indicators will be clarified. Qualitative tools will also be integrated into SEAMLESS-IF, to take into account institutional and social contexts. SEAMLESS-IF will be developed reflexively, using selected test cases to evaluate and improve the tools and assess utility. The development of SEAMLESS-IF will use participatory approaches to user involvement and dissemination, and to ensure applicability for prime users (EC DGs Research, Agriculture and Environment) and other users. SEAMLESS-IF will allow ex-ante analyses of the impacts of policy and behavioural changes, through clarification of the benefits, costs, and externalities associated with farming system management. Interactions between the EU, associated candidate countries and the rest of the world will be assessed by incorporating appropriate models. SEAMLESS-IF will rapidly become essential for integrated assessment of agricultural systems
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Arabidopsis genomic RNA interference knock-out line analysis' (AGRIKOLA).

assistant: **Innovation**

The AGRIKOLA project aims to create a set of 50000 plasmids for performing constitutive or inducible targeted gene-silencing using RNA interference (RNAi) on almost every Arabidopsis gene. At least 6000 of these plasmids will be used to transform Arabidopsis plants to obtain lines in which specific genes (covering the whole of chromosome 3) have been Post transcriptionally silenced. Several hundred of these silenced lines will be analysed in detail to prove the usefulness of this approach and to gain information on the function of important Arabidopsis genes. The plasmids and mutant lines generated during the course of research projects. Such silenced lines will be an invaluable resource for determining the function of Arabidopsis genes, and by extrapolation, the function of homologous genes in other organisms.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Translation of the direct-on-blood PCR-NALFIA system into an innovative near point-of-care diagnostic for malaria' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Accurate diagnosis of malaria is essential to timely install proper treatment. Current diagnostic methods for malaria have limitations, such as detection limit and problems with antigen persistence after successful treatment (rapid diagnostic tests) or may require technical expertise and equipment (microscopy). Treatment on the basis of clinical symptoms only (fever = malaria) must be abandoned.Molecular diagnostic tests (MDx) could circumvent some of the mentioned limitations, but tests are incompatable with the Point of Care concept as they require sample processing, have a contamination risk and complicated read-out systems. Although Real-Time PCR assays have overcome some of these problems, the need of large and expensive equipment and the inability to perform it directly on blood shows the need to further improvement and simplification of MDx.Building on the successful outcomes of EU FP7 project  “MALACTRES”, the current proposal aims to further built on the concept of a direct on blood PCR system combined with a simple read-out system. This concept has the following advantages:-Direct on blood: no DNA extraction or sample processing;-Simple read-out system (black/white), no need for gel electrophoresis or computer.The proof of concept was delivered in laboratory ring trials and field evaluations in Thailand and Burkina Faso. The proposed diagnostic will have the following additional features:-Direct on blood and simple read-out-Closed system: reduced risk of contamination-Stabilizing reagents included: increased shelf life, no cold storage-Cheap, quick, sensitive and specific.It is envisaged that a full marketable product will be available in 36 months. During development the consortium (dominated by SMEs) will also look into possibilities to adapt the developed s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Development of new chemical imaging techniques to understand the function of water in biocompatibility, biodegradation and biofouling' (BioWater), addressing dissemination and exploitation.

assistant: **Impact**

Water is the first molecule to come into contact with biomaterials in biological systems and thus essential to the processes of biodegradation, biocompatibility and biofouling. Despite this fact, little is currently known about how biomaterials interact with water. This knowledge is crucial for the development and optimisation of novel functional biomaterials for human health (e.g. biosensing devices, erodible biomaterials, drug release carriers, wound dressings). BioWater will develop near and mid infrared chemical imaging (NIR-MIR-CI) techniques to investigate the fundamental interaction between biomaterials and water in order to understand the key processes of biodegradation, biocompatibility and biofouling. This ambitious yet achievable project will focus on two major categories of biomaterials relevant to human health: extracellular collagens and synthetic biopolymers. Initially, interactions between these biomaterials and water will be investigated; subsequently interactions with more complicated matrices (e.g. protein solutions and cellular systems) will be studied. CI data will be correlated with standard surface characterization, biocompatibility and biodegradation measurements. Molecular dynamic simulations will complement this work to identify the most probable molecular structures of water at different biomaterial interfaces.Advanced understanding of the role of water in biocompatibility, biofouling and biodegradation processes will facilitate the optimization of biomaterials tailored to specific cellular environments with a broad range of therapeutic applications (e.g. drug eluting stents, tissue engineering, wound healing). The new NIR-MIR-CI/chemometric methodologies developed in BioWater will allow for the rapid characterization and monitoring of novel b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Flexible and resilient integrated biofuel processes for competitive production of green renewable jet and shipping fuels'.

assistant: **Concept**

The FLEXI-GREEN FUEL project will advance the production of next generation biofuels for shipping and aviation by developing and improving integrated technologies for a complete conversion of #1 lignocellulosic residue biomass (LIGN) and #2 the organic fraction of municipal waste (OFMSW). Project targets are to significantly reduce the cost by improving the performance of the produced biofuels regarding the efficiency, the environment and society. Semi-continuous organosolv pretreatment is used for the separation of cellulose and hemicellulose fractions from lignin, aiming at optimal conversion of each stream. As lipids are far superior bio-crudes towards hydrocarbon fuels, this project we will develop and optimize three efficient methods to convert sugars to lipids (fungal fermentation, algae dark fermentation and lipid rich larva production), which will be further converted via advanced hydrotreatment (HDO/isomerization) to diesel range (C16-C18) alkanes. We will combine this with the utilization of furans (from pentose/hexose sugars) via condensation (C-C coupling) and hydrodeoxygenation routes to allow production of drop-in aviation fuels. And with utilization of lignin fast pyrolysis via selective fractionation, hydrodeoxygenation and alkylation towards aviation fuels (C8-C17) and/or bunker type fuels (>C18). Whole system analysis assess economic (TEA) and environmental (LCA) performance indicators and benchmark against conventional aviation and shipping fuels.""


**Keywords:** Lignocellulosic residue, Organic fraction of municipal solid waste, jet-like aviation bio-fuels, bunker-like shipping bio-fuel, integrated conversion processes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Mitochondrial efficiency as a mechanism for local adaptation in a changing climate' to be submitted under Horizon 2020.

assistant: **Abstract**

The world is undergoing rapid environmental change, and organisms are growing up in environments very different to those in which they evolved. Predicting how organisms will cope with this unprecedented scale of change is a key priority of biological research. The proposed work will be a significant advance to the field by measuring the evolutionary potential of developmental thermal physiology across natural populations, testing an underlying mechanism mediating adaptation to a warmer climate: namely the thermal sensitivity of mitochondrial efficiency (ATP/O). Outcomes will advance both basic biological knowledge, and applied climate change responses which are of importance to EU citizens, by testing individual- and population- level variation to predict species-level responses to climate change, and identifying a potentially general mechanism for thermal adaptation that can focus conservation efforts. I will use a combination of field work with laboratory measurements and techniques on natural populations of a widely distributed freshwater fish, and meta-analytical techniques, to target the following novel objectives: Objective 1) Test for divergence in mitochondrial efficiency (ATP/O) and developmental thermal physiology across locally adapted populations spanning a wide latitudinal gradient; Objective 2) Identify how developmental temperature affects ATP/O; Objective 3) Determine how selection and heritability of developmental thermal physiology varies across populations, and how ATP/O may mediate temperature-dependent selection; Objective 4) Summarise the generality of patterns between ATP/O and environment across species using meta-analysis. This project will draw from and expand upon the combined research track-records and strengths of my work in early-life histo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Twin-model based virtual manufacturing for machine tool-process simulation and control' (TWIN-CONTROL).

assistant: **Concept**

Europe is the world’s largest manufacturer of machine tools but this position is threatened due to the emergence of Asian countries. However, Europe has world-class capabilities in the manufacture of high-value parts for such competitive sectors like aerospace & automotive and this has led to the creation of a high-technology, high-skill industry. European machine tool builders, part manufacturers and other agents have to work together to increase the competitiveness of European manufacturing industry.Simulation tools are currently a key complement to European machine tool industry expertise but new integrated approaches are needed. The main objective of Twin-Control is the development of a simulation and control system that integrates the different aspects that affect machine tool and machining performance. This holistic approach will allow a better estimation of machining performance than single featured simulation packages, including lifecycle concepts like energy consumption and end-life of components. This integrated concept will also enhance the necessary collaboration between machine tool builders and part manufacturers.The specific industrial objectives are:•         Getting machines that work as designed faster (10% reduction)•         Getting production processes that work as planned faster (20% reduction)•         To get a first-time-right part manufacturing (75%)•         To increase production time trough model-based control (increase of 1-2%)•         To reduce energy consumption (25-50%)•         Improve machine reliability and increase machine up-time due to a proactive maintenance (2-4.5%)All these will contribute to reduce machine tool life cycle costs (15 %) with a reduction of O&M costs in the range of 25%.The project considers the validation and dem
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Data-Efficient Scalable Reinforcement Learning for Practical Robotic Environments' in the context of a Horizon 2020 call.

assistant: **Objectives**

The robotics industry is in the process of greater adoption of machine learning. Recent reinforcement learning (RL) and AI breakthroughs, such as AlphaGo, rely on collecting large amounts of data. Such methods are unsuitable for real robots which often can only afford a few trials. Moreover, some states are unsafe to explore, e.g. running over a cliff. Conversely, works such as PILCO combine Bayesian models with model-based RL to improve data efficiency. Those frameworks typically thrive in small data regimes. The goal of this project is to develop RL algorithms that scale to high dimensions while learning with less data. The main pillars of our methodology are RL, recurrent networks, Bayesian methods, embodied exploration, and optimization. To tackle the data efficiency, we adopt model-based RL approaches. We plan to combine representation learning and dynamics in a single model, leading to high predictive power and low-dimensional internal state spaces. Notably, we use methods that can learn disentangled representations, e.g. infoGAN. In practical robots, effective exploration is a real problem in current approaches. We want to leverage recent works in embodied exploration by the host group which allows various real-world robots to explore their capabilities in minutes of interaction. I received my Ph.D. for work in optimization with Dr. William Hager. I also conducted postdoctoral research in machine learning. The Autonomous Learning group is led by Dr. Georg Martius, who has previously studied artificial intrinsic motivation, the self-organized exploration of sensorimotor coordination via information theory, and internal model learning. He also developed the robotics environment LPZRobots. I will gain extensive experience in practical robotics, embodied exploration,