RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Hygienic coatings with active ingredient controlled release' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Current applied hygienic coatings are vulnerable to microbial surface colonisation: they may be reservoirs of bacterial and fungal contamination, and being on surfaces in food processing areas and in hospitals, can create danger to health. Moreover, nowadays, a more restrictive legislation is being introduced in the fields related to the safety and health of the sanitary places. Therefore, there is an urgent need for improvement in hygienic surfaces.In this project, it is proposed a novel approach in order to avoid microbial surface colonisation in sanitary places. Thus, a high tech coating will be developed by means of the incorporation of reservoirs containing anti bacterial active ingredients (biocides), which will be released in a controlled way. The successful completion of the objectives of HYCORE project requires a multidisciplinary and open approach comprising the participation of a wide variety of partners with complementary expertise is required: ITECH and ARMINES have a wide experience in the field o f micro-encapsulation, polymer grafting and micro-gels. BARBOT, OIKOS, LIPPENS, URSAN are coatings manufacturers with vast experience in the field of the development and production of coatings for various applications.Their expertise in this field will be complemented with the wide experience that CIDEMCO has on the development and characterization of coatings for the most diverse applications. THOR is a company dedicated to the manufacturing of biocides for several industrial sectors and with a vast knowledge regarding Active Ingredients for the most various applications. AQUA+TECH and ZIMTEC are companies that manufacture HighTech specialty Chemicals and microcapsules, which among other applications, are used for the controlled release of substances. PROTE C is
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Indicators and Quantitative Tools for Improving the Process of Sustainability Impact Assessment' (2002-2006).

assistant: **Concept**

I.Q. Tools aims to give an evaluation of the policy at the initial stage of the proposal: given the policy draft produced by the Commission, with the I.Q. Tools it is possible to assess the potential effects of the policy on the three dimensions of sustainability if these effects lead to the sustainable objectives or not and the significance of these impacts. The objectives of the project can be characterised by the three key outputs. Output 1 is an indicator review and a list of key indicators for priority areas. This includes a review of existing assessment practices that try to integrate more than one dimension of sustainable development. Output 2 provides a decision-support tool for SIA. The specific decision support tools will be a desktop software including-
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Molecular signatures and Modulation of immunity to Adeno-Associated Virus vectors' (MOMAAV) under Seventh Framework.

assistant: **Objectives**

Experience with adeno-associated virus (AAV) vector-mediated gene transfer in human trials has unveiled the therapeutic potential of this approach, with some of the most exciting results coming from clinical studies of gene transfer for hemophilia B, congenital blindness, and the recent market approval of the first AAV-based gene therapy in Europe. Follow-up data of subjects treated with AAV vectors is showing sustained correction of the disease phenotype for several years after gene transfer, and recent data confirmed that AAV vectors can drive expression of a transgene in humans for >10 years. With clinical development, however, some of the limitations of the approach, not entirely identified in preclinical studies, became obvious; in particular it is well established that the host immune system represents an important obstacle to be overcome in terms of both safety and efficacy of gene transfer in vivo with AAV vectors. The overall goal of this proposal is to gain critical, missing knowledge on the interactions between AAV vectors and the immune system in order to develop strategies to achieve safe, effective, and long-lasting gene transfer in humans.In this proposal we will: 1) Define the molecular signatures of the immune system in humans undergoing gene transfer with AAV vectors using cutting-edge, high-content immunophenotyping technologies; 2) Study the role of anti-AAV antibodies as determinants of AAV capsid immunogenicity using both in vitro and in vivo systems; 3) Identify novel pharmacological and cellular approaches to overcome T cell immunity to AAV; 4) Develop novel strategies to overcome pre-existing antibody responses to AAV.This proposal exploits the knowledge and the skills available in our lab to develop new tools and to provide novel, basic insight
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Cooperation between NCPs for Horizon 2020 Societal Challenge 2 on “Food Security, Sustainable Agriculture and Forestry, Marine, Maritime and Inland Water Research and the Bioeconomy” and the Key Enabling Technology - Biotechnology' (BioHorizon).

assistant: **Concept**

The overall idea of the BioHorizon proposal is to establish innovative and mutually learning pan-European platform for transnational activities of NCPs involved in the SC2 and KET-B. The aim is also to create a network of NCPs exploiting the synergies of acquired and distributed knowledge, collective development and trainings, in which all NCPs can learn from each other, thus increasing mutual understanding of different approaches and requirements in the daily work of an NCP. The network will develop novel, high quality services provided to SC2 and KET-B beneficiaries. The excellent assistance provided by BioHorizon will go beyond typical NCP services, since the established network will put an emphasis on complex and multidisciplinary aspects of Horizon 2020, including widening participation of the EU 28. The methodology applied to achieve the objectives includes: trainings, workshops addressed at NCP needs identified during the evaluation of current activities,, networking staff exchange programme, e-mentoring scheme and trans-national brokerage events. Furthermore, based on the results of the previous project, the new BioHorizon will greatly improve and enhance capacity building and networking opportunities by continuing with activities and measures proven to be successful, but also including new elements. BioHorizon will fully cover activities that include innovative and efficient training of NCPs across Europe, thus helping to simplify and increase access to H2020 calls, lowering barriers for newcomers and improving the quality of proposals submitted. Special attention will be given to networking and improved collaboration of the ICPC NCPs, supporting and increasing their integration with the European NCPs. BioHorizon aimes to generate high impact on different level
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Improved and eNhanced  Stakeholders Participation In Reinforcement of Electricity Grid' in the context of a Seventh Framework call.

assistant: **Objectives**

The basic assumption of the project is that the difficult public acceptance of Electric Power System (EPS) infrastructures are due to several  reasons: i) the lack of trustworthiness in the relationship between Transmission System Operators (TSOs) and the stakeholders and general public; ii) the difficulty in comparing the new EPS infrastructures benefits, which are on a global, with the impacts , which are mostly “local”; iii) the perception of risks, threats and problems for the stakeholders, often neglected or scarcely recognized and understood by TSOs; iv) the lack of tools to facilitate the stakeholders and public participation to decision processes; v) the fragility or the complexity of the participatory processes, with the consequent  very low effectiveness. The project idea, therefore, includes:1. the analysis of the needs, concerns, wants and expectations of the stakeholders and general public2. the development or adaptation of methodologies  to assess impacts and benefits3. the development of suitable processes for an effective communication and real participation of the stakeholders and general public4. a series of case studies (taking into account geographical location, size of the infrastructure and stage of completion of the scheme), with a double aim: to give elements to the methodological activities and to allow a proper testing5. a synthesis of the project results and a series of recommendations about the stakeholders and general public engagement6. the dissemination of the project results and outputThe overarching goal of this proposal is to develop a methodology to manage the consultation in order to engage the stakeholders in the decision making process and to improve support of development of future grid infrastructure. Based on multidisciplinary ap
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Seminars preventive conservation and monitoring of the architectural heritage' (SPRECOMAH) under Sixth Framework.

assistant: **Objectives**

There is an increasing interest for preventive conservation strategies and a need is felt to direct research interest towards the need expressed by the practitioners and educators. The preventive conservation approach including the need for monitoring and maintenance is based on a commonly accepted understanding that prevention is more effective than curing. 2 Seminars on PREventive COnservation and Monitoring of the Architectural Heritage will be organised with the input of 9 partners from 6 European Countries, which have a specific professional or research experience with conservation. Each seminar will accept up to 50 participants, for 20 of them a grant is available.The seminars aim at:1. Sharing and analysing, amongst professionals, post-graduate students and researchers from all over Europe and countries at the Mediterranean Sea, the good practices based on many years of professional experience with preventive conservation developed by Monumentenwacht in Flanders and The Netherlands;2. Sharing research results that address issues of which preventive conservation strategies can benefit; vast amount of valuable research results from EC and other research projects can contribute to support the importance but also the development of tools to strengthen this approach (examples: Damage Atlas, Masonry Damage Diagnostic System, RECORDIM initiative).3. Identifying research strategies at the European level through gathering of researchers, practitioners and professionals that will promote preventive conservation and that will strengthen preventive conservation oriented organisations to improve the effectiveness of their work.4. Generating and publishing (on internet and in publications) lasting reference materials for researchers, for professionals and authorities on preven
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'A NOVEL RECONFIGURABLE BY DESIGN HIGHLY DISTRIBUTED APPLICATIONS DEVELOPMENT PARADIGM OVER PROGRAMMABLE INFRASTRUCTURE'.

assistant: **Innovation**

Given the inability of Highly-Distributed-Application-Developers to foresee the changes as well as the heterogeneity on the underlying infrastructure, it is considerable crucial the design and development of novel software paradigms that facilitate application developers to take advantage of the emerging programmability of the underlying infrastructure and therefore develop Reconfigurable-by-Design applications. In parallel, it is crucial to design solutions that are scalable, support high performance, are resilient-to-failure and take into account the conditions of their runtime environment. Towards this direction, the ARCADIA project aims to design and validate a Novel Reconfigurable-By-Design Highly Distributed Applications Development Paradigm over Programmable Infrastructure. The proposed framework will rely on the development of an extensible Context Model which will be used by developers directly at the source-code level. Proper Context-Model will be assisted and validated by IDE-plugins (for many IDEs) in order to re-assure that the generated executable files contain meaningful semantics.  According to ARCADIA’s vision, the generated executables should be on-boarded by a Smart Controller which will undertake the tasks of translating annotations to optimal infrastructural configuration. Such a controller will enforce an optimal configuration to the registered programmable resources and will pro-actively adjust the configuration plan based on the Infrastructural State and the Application State. The Context-Model and the aforementioned ARCADIA toolset will be complemented by a Development Methodology that will assure that developed Highly Distributed Applications are Reconfigurable-By-Design. The framework is planned to be validated and evaluated on three use cases
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Feasibility Study for a Breakthrough Core System to Enable Fault Tolerant Manufacture of High Performances Composites Wind Blades' (KORIDION).

assistant: **Innovation**

KORIDION project is aimed to provide a simple yet effective solution, transferring positive results applied in protective equipments (helmets), to composite materials applied for wind blade structures.  The advantages provided within the system enable to improve the load capacity of the structure, adhesion from skin and core, and more relevant to the end performances, to constitute a system which can be easily automated, contemporarily reducing the potential impacts of errors in manual operation.  Innovative material and processing mechanisms are at the forefront of the project objectives, oriented to revolutionize the way blades are designed and manufactured. The basic KORIDION formula and the processing means have been developed within SmartNets EU project (G.A: 262806) in cooperation with the UK company Tryonic Ltd. Tryonic owns the IPR generated and THURCKON has the rights for use and further exploitation of the five patents developed.The project is expected to generate relevant growth for THURCKON that foresee to reach, in a short-medium term (2-4 years), revenue of about 2.3 M€ (low success scenario) and to hire a minimum of 4 employees.The final objective is to demonstrate the feasibility, also through a reduced scale blade application, that can effectively constitute a basis for a successful Step2 project, oriented to the successful transfer of the overall approach at a full scale wind turbine blade.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Molecular Mechanisms of Dynamic and Spatial Control of Eph Receptors clustering' (DynaSpaCER), addressing dissemination and exploitation.

assistant: **Impact**

There is mounting evidence that the spatial and temporal organization of ligands at cell-cell interfaces modulates signaling. In particular, for Eph receptors and their ligands (ephrins) this phenomenon is widely recognized but poorly understood due to difficulties in controlling and analyzing membrane protein microenvironments at the nanoscale. A combination of different techniques ranging from DNA nanotechnology to high resolution microscopies via standard biochemical techniques and computational tools will be used to provide a molecular understanding of the roles of the spatial and temporal organization of ligands in receptor signaling. Substrates that recreate the intramembrane signalling geometry at cell-cell contacts are designed and produced by employing ligand decorated DNA nanostructures anchored on artificial supported lipid bilayers. This allows an unparalleled control of spatial distribution of the ligands and their dynamics. TIRF/STORM super-resolution microscopy is used to measure size and dynamics of clustering and biochemical assays will quantify the receptor spatial distribution and activation levels. Together with computational simulation and modeling of clustering dynamics, these efforts will lead to a molecular mechanism of spatial organization of ligands and receptors during clustering and how this affects signaling.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Vendian and paleozoic accretionary history of high arctic - polar urals, novaya zemlya, and taimyr' under Fourth Framework.

assistant: **Concept**

Research objectives and content The High Arctic is a key link in the plate tectonic evolution of northern Eurasia. Results from this investigation will lead to i) a model for the tectonic evolution of the High Arctic, and ii) model integration with existing scenarios for the tectonic evolution of northern Eurasia and the northern Atlantic region. These objectives will be achieved with field-work (mapping and structural analysis) and geochemical analysis (elemental and isotopic) in the Polar Urals (to characterize the composition and age of the volcanic and ophiolitic sequences present, correlate them where possible, and characterize their basement), in Taimyr (to determine the time of suturing of the thrust- bounded terranes), and in Novaya Zemlya (to understand the relationship between the Baikalian orogeny and thrusting). The resulting structural, geochemical, and geochronological data will enable me to determine the tectonic provenance of the accreted terranes, reconstruct the tectonic history of the Polar Urals, and compare this evolution with existing models for northern Eurasia and possibly the northern Atlantic region. The geochemical techniques (both conventional and innovative high-resolution ion-probe) to be used include XRF for major and trace elements, IDMS for REEs, and conventional mass spectrometry for Rb/Sr, Pb/Pb, U/Pb, and Sm/Nd. Plagiogranites, xenoliths, and migmatites will be analyzed using the Cameca 1270 ion-probe at LIG. Training content (objective, benefit and expected impact) Objectives: 1) To increase and broaden existing geologic and geochemical skills. 2) To acquire new knowledge of state-of-the-art, high resolution ion-probe technology using the Cameca 1270 (in Stockhom), the only high resolution ion-probe of its kind in Europe. Benefits an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Nutritional enhancement of probiotics and prebiotics: technology aspects on microbial viability, stability, functionality and on prebiotic function'.

assistant: **Concept**

The purpose of the project is to address and to overcome specific scientific and technological hurdles that impact on the performance of functional foods based on probiotic- prebiotic interactions such as lack of strong knowledge on the primary factors for probiotic viability, stability and performance as well as on probiotic- prebiotic interactions. The project will (1) systematically explore effects of processing on functionality of probiotics and on probiotic performance, (2) apply selected processing techniques for prebiotic modification and (3) use the information generated for new process and (probiotic-prebiotic) product options. Expected achievements include the identification of critical process parameters for probiotics and prebiotics, optimisation of probiotic viability and stability at pilot plant scale and processing induced new prebiotics. The project is highly interdisciplinary with strong industrial participation and commitment.