RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Disruptive Technologies Supporting Labour Market Decision Making' (HECAT).

assistant: **Concept**

Hecat aims to investigate, demonstrate and pilot a disruptive technology to support labour market decision making byunemployed citizens and those seeking to help them. At one stage or another, almost half of all EU citizens will rely on aPublic Employment Services (PES), and so this is a key touchpoint of a contemporary state and has impacts on citizen’sthinking about social cohesion, care and existential wellbeing. The ambition of the project is to improve citizen’s experienceand outcomes of unemployment by offering real-time evidence-based insight into their personal position in the labourmarket. Hecat builds on the experience and learning of existing basic algorithmic techniques used by some European PESadministrations to: - deliver labour market insight directly to unemployed citizen and so is built on European values of opendata, collaboration, transparency and citizen-participation - broaden out the focus on quantity of jobs drawn from the‘economic imagination’ to add a focus on job quality and sustainable employment - go beyond profiling the ‘stock’unemployed people, to incorporate measures of labour demand, and so take a labour market approach - go beyond theprofiling of ‘problem categories’ of citizens that current survey-data based systems use, to exploit emerging big-dataprocessing and analytics to treat each individual as a unique complex subject in a real-time and near limitless database thatleverages the insight trapped inside statistical agencies - frame the development in deep contextual insight into the originand transformation of the experience of unemployment and its administration based on anthropological inquiry - bring thisinsight into the hands of decision makers with a a platform-UX that exploits novel artificial intelligence with learningcapabil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Access to chiral pyridine derivatives via catalytic asymmetric synthesis'.

assistant: **Concept**

Pyridine and its derivatives are abundant structural motives in nature and widely used in medicinal chemistry. In this research program we propose to develop catalytic enantioselective methods for the synthesis of chiral pyridines with tertiary and quaternary stereocenters through the catalytic addition of readily available and highly reactive organometallics to conjugated alkenyl pyridines. Furthermore, the proposed methodology will be used for the generation of contiguous stereocenters via sequential conjugate addition/Mg-aza-enolate trapping strategies. The synthesis of this kind of chiral compounds will permit further functionalization of pyridine products through the partial or total hydrogenation reactions of aromatic pyridine rings, or the introduction of different electrophiles in various positions of the aromatic ring.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Enhanced chitin-based biosorbents for drinking water purification' under Seventh Framework.

assistant: **Concept**

The project represents a technical and technological contribution to purification of polluted drinking waters by selective biodegradable sorbent derived from biowastes.ChitoClean will implement a holistic approach taking into account all necessary steps of a novel drinking water treatment process. This approach is centred on chitin-based biosorbents, which are already used in different applications and known for their excellent adsorption capacities. Natural materials made from carcasses of shrimps and crabs are to be physically and chemically enhanced to be suitable for the use in drinking water purification applications. The characteristics that the Enhanced Chitin-based Materials (ECM) will ideally present are improved stability, adaptability to different forms of filters and maximal adsorption rates and capacities.ECMs are to be implemented in prototypes of filtering units. Different kinds of prototypes will be generated in order for the new technology to be applicable for different use: household filters, on-site water treatment in wells, big-scale treatment and integration into central water supply systems of small towns. In parallel products and processes will be tested in order to regenerate charged filters and extend their lifetime of the latter. As – despite material regeneration - ECM will eventually lose its absorption capacity and be ‘spent’ needing replacement, the project also investigates on methods to recycle and/or dispose of the ‘old’ filter material. In addition, the health aspect will be taken into account by evaluating the effect of the treatment by ECM on the mineral content/balance of the purified water.First discussions towards validation of results by potential customers are supposed to take place within the External Advisory Board regrouping r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Training on optical devices, configurations and techniques applied in biomedical optics' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

The Applied Optics Group in the School of Physical Sciences, University of Kent at Canterbury (UKC) has a number of Marie Curie postgraduate training fellowships within the EU Framework 5 Program. The program is intended for young researchers pursuing their doctoral studies in a country different than that of the host and willing to receive high-level research training in a specialized area of research. Research training is offered in the following subjects: optical scanning, optical coherence tomography, interferometry, sensing, optical sources and optical devices for non-invasive imaging of tissue. The experimental work is performed in an academic setting, where research and teaching are integrated. The fellow will spend >75% on her/his research project under daily guidance of two permanent staff members. The additional time is available for specialized theoretical courses and studies on various subjects of interest. Eligibility criteria are specified under cordis.europa.eu/improving. Fellows must be doctoral students of an university in a Member State of the EU or in an Associated State to the EU. The applicants must have a good background in theoretical and experimental optics and expected to have graduated in Physics, Medical Physics or Electronic engineering. We are looking for highly imaginative and self-motivated individuals. Allowance: 1200 Euros/month subsistence + travel expenses, duration10 months, age: 35 or less. Fellowships will be based in Canterbury. UKC, located in the southeast of England, thrives on its European links while at the same time is a 80 minute drive from London. UKC is an equal opportunity employer and female candidates are especially encouraged to apply. The group could host 2 fellows/year for four consecutive years starting Jan. 2002. T
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Pedagogies of Educational Transitions', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The project - Pedagogies of Educational Transition (POET) - brings together experienced and early career researchers from universities in five countries to build expertise and skills, and strengthen international research partnerships in the area of researching young children's educational transitions. The proposal outlines staff exchanges and networking activities which will build sustainable research collaborations and provide the basis for the establishment of a European research centre of excellence. Working from the concept of the ""knowledge triangle"" in which education, research and innovation are stimulated through international collaboration on a shared topic, POET is as collaboration between three European nations, Sweden, Scotland (UK), Iceland and two international partner countries: New Zealand and Australia, each with an S&T agreement with the EU.The POET project is based on the premise that positive early educational transition experiences are a key element of the sustained educational engagement of children and families over time. The project will work with five themes of pedagogical transitions: pedagogies of inclusion, indigenous pedagogies of transition, pedagogies of continuity, pedagogies of transition over time, pedagogical beliefs and practices with the aim of reconceptualising educational transitions cross nationally. These themes will be addressed through the following questions:1. What are the dominant and emerging pedagogies of educational transition2. What research models and approaches exist to describe and explain educational transitions3. How are these transitions theorised4. What evidence-based recommendations for national and international action (research, policy and practice) can be made as a consequence of POETThe project aims to map
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Prospect for vaccine immunomodulation through dendritic cells at mucosal membranes', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

Dubravca Grdic is a devoted and very talented young scientist. She trained with me for her PhD and I have had a close and rewarding collaboration with her for over 4 years. Her particular strength is her commitment to science and her persistence in pursuing her research tasks. Dubravka is well qualified to establish her own research group and she has shown excellent qualifications in organizing her and other peoples work. She is technically skilled and masters many techniques currently on demand in biomedical science, especially techniques used in cellular immunology. Her research has focused around the mucosal membranes and her main goal has been to dissect regulatory factors that control induction of mucosal immune responses. She took an imaginative approach to resolve the mechanisms that control why some encounters with intestinal antigen result in tolerance, while others result in active IgA immunity: The principle was to use antigen conjugated to cholera toxin or its B subunit and administer these orally to IL-4 gene targeted mice. Since the only difference between these conjugates is the ADP-ribosylating ability of cholera toxin, missing in Ihe B.subunit, it was clear that cells targeted by conjugates carrying antigen, respond to ADP-ribosylation by enhancing immune responses. In the course of these studies it became evident that a major target population for cholera toxin at mucosal membranes is the dendritic cells. She undertook elegant experiments at the cellular and molecular level that described the interactions between cholera toxin and dendritic cells. Dubravka is now seeking financial support to continue her studies in the well renowned laboratory of Prof. Paola Ricciardi-Castagnoli in Milan. The decision to enter into a collaborative project with Prof. Ca
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Face Off. Understanding Ancient Masks' in the context of a Horizon 2020 call.

assistant: **Objectives**

“Face Off” is designed as an interdisciplinary project, whose main goal is the first comprehensive investigation and comparison of masking phenomena in the Iron Age Mediterranean (c. 12th-2nd centuries BC), aiming to explain why humans need masks and understand the connection between masks and ancient societies. Apart from focusing on the examination of the Aegean, Cypriot and Phoenician/Punic corpora of masks, this project will use scientific methods (i.e. 3D modelling, pXRF, Face Expression Recognition; Machine Learning) to investigate the transmission of mask models and the impact of ancient masks on the spectators, and to understand the age and gender of the characters represented in these faces, of the persons wearing the masks and of those attending the masked activities. A project on this chronological and geographical coverage and based on such multidisciplinary methodology is unprecedented. Investigating this complexity will provide insights into the role that masks played in some Iron Age communities across the Mediterranean basin. This project is designed to take place at Universitat Pompeu Fabra, which has the expertise, facilities and resources necessary to support such research. By viewing the ancient masks of the Iron Age Mediterranean through the lens of various disciplines and scientific methods, the proposed project entails a significant component of an exchange of knowledge, together with training through research. With its dissemination (seminar, publications) and public engagement activities (articles, lectures, exhibition), this project constitutes an innovative way of doing archaeology and intends to bring together different traditions within the European schools of Mediterranean archaeology.


**Keywords:** Ancient Masks, Iron Age Mediterranean,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'A unIfied framework for multimodal content SEARCH' to be submitted under Seventh Framework.

assistant: **Abstract**

I-SEARCH aims to create a novel unified framework for multimedia and multimodal content indexing, sharing, search and retrieval. I-SEARCH will be the first search engine able to handle specific types of multimedia (text, 2D image, sketch, video, 3D objects, audio and combination of the above) and multimodal content (gestures, face expressions, eye movements) along with real world information (GPS, temperature, time, weather sensors, RFID objects,), which can be used as queries and retrieve any available relevant content of any of the aforementioned types and from any end-user access device. Towards this aim, I-SEARCH proposes the research and development of an innovative Rich Unified Content Description (RUCoD). RUCoD will consist of a multi-layered structure, which will integrate descriptors of all of the above types of content, real-world information, even non-verbal yet implicit, emotional cues and social descriptors, in order to better express what the user wants to retrieve. Another objective of I-SEARCH is the development of intelligent content interaction mechanisms, including personal, social-based and recommendation-based relevance feedback and novel interoperable multimodal interfaces. This will result in a highly user-centric search engine, able to deliver to the end-users only the content of interest, satisfying their information needs and preferences, which is expected to dramatically improve end-user experience and offer new market opportunities. Furthermore, I-SEARCH introduces the use of advanced visual analytic technologies for search results presentation in order to facilitate their fast and easy interpretation and also to support optimal results presentation under various contexts (i.e. user profile, end-user terminal, available network bandwidth, int
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Effects of sleep deprivation and adrenergic inhibition on glymphatic flow in humans' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

Sufficient sleep is a key determinant of health, and sleep loss is associated with severe health risks. Nevertheless, the reason for why we sleep is not yet understood. Recently, a molecular function of sleep was described in rodents. The ‘glymphatic system’ (GS) is a sleep dependent macroscopic pathway of the brain that facilitates the removal of metabolites, including amyloid-beta. This project will for the first time reveal a sleep-driven human GS and show whether glymphatic flow (GF) can be linked to cognitive impairments associated with sleep loss. Secondly, I will promote GF with the adrenergic antagonist Carvedilol. This manipulation of glymphatic clearance may define new approaches for treating sleep-disorders and Alzheimer’s disease, or reduce or delay our need for sleep. I will investigate the human GS by applying state of the art, 5-10 Hz, ultra-fast MR sequences across sleep and wakefulness. Preliminary data show that these sequences enable the detection of cardiac, respiration, and slow pulsations, previously considered noise in fMRI imaging and distorted by aliasing effects. These pulsations are now believed to drive GF. The project will be a major step forward for sleep and neuroscience research, but also provide a key step in my career, demonstrating independent work and allowing me to learn advanced data-analysis skills and develop a novel imaging method, which I can apply in future studies. The chosen host institution is perfectly situated for the project, as they have established expertise and an exceptional skill-set in analyzing novel neuroimaging data including ultra-fast MRI. Secondly, my host provides unique infrastructure that allows for completion of the study, with key personnel in neuropsychology and data-analysis, as well as the world leadin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Uncovering Enteric GLIA-MACrophage communication in the intestinal homeostasis and inflammation'.

assistant: **Innovation**

Uncovering Enteric GLIA-MACrophage communication in the intestinal homeostasis and inflammation.The enteric nervous system (ENS) is a network of neurons and enteric glial cells (EGCs) organized in ganglia essential to control gastrointestinal physiology. Although EGCs have historically been described as supporting cells for enteric neurons, recent data from my previous work and from my host group demonstrated that enteric glia is “communicating” with innate immune cells via the secretion of immune-active molecules. Interestingly, alterations in the morphology and function of EGCs have been reported in patients affected by chronic intestinal inflammation such as inflammatory bowel disease (IBD). Thus, I hypothesise that factors released by enteric GLIA may directly modulate MACrophage phenotype and function in the gut, making EGC a novel overlooked player in the pathophysiology of IBD. In the first part of GLIAMAC, the molecules and the molecular mechanisms involved in the enteric glia-macrophage crosstalk will be screened in vitro using co-culture experiments and assessed in vivo using novel EGC-specific mouse models of intestinal inflammation. Finally, I aim to translate our findings to the clinical setting using tissue samples from IBD patients. To this end, the immunomodulatory properties of EGCs isolated from healthy individuals and IBD patients will be compared using cellular, genomic and proteomic system-wide approaches. Identification of new molecules and pathways involved in enteric glia-immune cell crosstalk will represent a major breakthrough in elucidating the pathogenesis of intestinal immune-mediated diseases. Thus, GLIAMAC will potentially give rise to a new class of molecules to treat and favour remission in patients affected by IBD.


**Keywords:** Infla