RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Urinary bladder bioprinting for fully autologous transplantation' under Horizon 2020.

assistant: **Concept**

A number of conditions, including trauma, inflammation, incontinence, overactive bladder, renal impairments, neurological disorders (like spinal cord injury or spina bifida) and cancer, require bladder augmentation. For almost a century now, the majority of cystoplasties utilize bowel segments (enterocystoplasty). This, almost a century years old, gold standard practice bears numerous risks and complications affecting the majority of patients, thus compromising the quality of life while burdening the health care systems. This has fuelled efforts towards the development of engineered bladder tissue. Advancements in bioprinting technologies are increasingly employed in regenerative medicine but mostly in smaller and less complicated tissues. UroPrint proposes the use of Laser Induced Forward Transfer (LIFT) to generate bladder tissue for autologous transplantation that would meet the biological, mechanical and functional properties of human bladder. To this end, primary urothelial and smooth muscle cells will be obtained from healthy donors and expanded in fully Good Medical Practice compliant methodologies. These will be combined with novel natural autologous scaffold material obtained from platelet lysates. Then, a novel approach in the generation of bladder transplant will be utilized, combining intestine denudation and in vivo printing during surgery using a novel prototype LIFT printer that achieved high spatial resolution (<10 μm), high cell viability (>95%) single-urothelial cells.


**Keywords:** Urinary bladder engineering, autologous biometarials, Laser InducedForward Transfer of cells, laser bioprinting, in vivo laser bioprinting
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'BOTFIND:  Finding Bots, Detect Harassing Automation, and Restoring Trust in Social Media Civic Engagement' (BOTFIND) under Horizon 2020.

assistant: **Objectives**

Social media platforms have become tools for manipulating public opinion during elections. In particular, “bots” are algorithms that automate rapid, widespread interactions with citizens, often with deleterious effects on public knowledge of science, social inequality, and public policy options. Through the ERC COMPROP Consolidator award, researchers have demonstrated that even simple bots (i) effectively keep negative messages and fake news in circulation longer (ii) target journalists and civil society groups and (iii) operate with little oversight from social media firms. Such algorithms have negative consequences both for public trust in technology innovation and for the quality of public deliberation in Europe’s democracies. ERC researchers have been able to identify highly automated, politically-manipulative social media accounts post hoc. This project will allow researchers to take what we have learned and produce an online tool that allows people to evaluate suspicious social media accounts. Most social media platforms are slow to address troll and bot activity, so this innovative tool will put ERC research into public service in Europe—and around the world.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Forest Carbon Flux and Storage Mapping Service' (ForestFlux).

assistant: **Innovation**

Forest Flux will revolutionize forestry value added services in Earth Observation (EO) by creating and piloting a cloud-based service for committed users on forest carbon assimilation and structural variable prediction using Copernicus data. The revolution is driven by sustainable forest management and anticipated by EU forest strategy, the Bioeconomy Action Pan, and the demands of environmentally aware end-users of wood industry products. Until recently, detailed information on forest carbon cycle has not been available due to a lack of scientific understanding, spatial data availability, limited processing capacity, and the complexity of implementing this information in business processes. Forest Flux will use the explosive increase in high-resolution EO data by Copernicus program and developments of cloud computing technology. It will implement world-first service platform for high-resolution maps of traditional forestry variables together with forest carbon fluxes using a holistic approach in a single processing chain. By the end of the project, forestry and carbon data will be completely integrated into the decision-making processes of selected core users and establish the leadership of European industry in sustainable utilization of forest resources. The relevant algorithms have been recently demonstrated by consortium partners. The computing infrastructure is specifically targeted for EO data and forestry users, and will be fully functional by the end of the project. The web-based human and machine interfaces will allow market access unrestricted by country boundaries and facilitate easy commercial interactions of players of different sizes and backgrounds. Dedicated user involvement, strong commercial interests, rapidly developing online markets, and demonstrate
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Next level real-time characterisation of Li- and Na-ion batteries by – Automatic Tuning Matching Cycler (plus Goniometer) – ATMC(+G) in situ NMR' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Concerns about finite energy resources and the need to decrease greenhouse gas emissions have increased the use of intermittent renewable energies on the electric grid. This is not without its challenges requiring more efficient ways to store electrical energy to balance demand with supply. Li-ion batteries (LIBs) are the most desirable form of energy storage (high energy / power densities) but an increasing demand of Li commodity chemicals combined with geographically-constrained reserves will drive up prices in the future. Due to the high abundance, low costs and very suitable redox potential, Na-ion batteries (NIBs) should open new avenues of research and engineering as complementary alternatives to LIBs. This shift has to be accompanied with a deeper understanding of the chemical reactions involving the multiple cell components.The proposed project focuses on a next step of in situ NMR spectroscopy, offering the unique possibility of non-invasive real-time studies of batteries under operating conditions – to track the formation of intermediate phases and investigate electrolyte decomposition during cycling of LIBs and NIBs. Significantly different shifts of the multi-component samples, resonance broadening as well as interferences of the NMR and external battery cycler (EBC) circuit impair the experiments. Hence, we will set up a novel NMR probe system allowing “on-the-fly” adjustment of the NMR circuit during the measurement and sample orientation changes via an automated goniometer. Moreover, an entirely new NMR-EBC-connection design will benefit the real-time experiments. This next level Automatic Tuning Matching Cycler (plus Goniometer) – ATMC(+G) – in situ NMR approach will be established in a comparative study on lithium vs. sodium iron phosphate cathodes in L
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Developing smart polymer compositions for highly sensitive multiplex PCR assays' (Smartpolymer), addressing dissemination and exploitation.

assistant: **Impact**

The project aims at designing, synthesizing and optimizing thermothickening polymer compositions that would behave as liquid miscible with water, exhibit a low viscosity at room temperature and turn into a homogeneous hydrogel during PCR with MCT assay, with the limited diffusion of the DNA target and PCR products and high enough diffusion of PCR reagents to permit efficient DNA amplification. For this purpose copolymers consisting of a water-soluble backbone with side chains exhibiting LCST will be the topic of choice. The proposal is very innovative because in the first time thermothickening polymers will be applied in MCT PCR assays allowing fast, sensitive and selective quantifying multiple targets within the single reaction. The contribution of the project will be in digitalizing assays and making multiple target quantification straightforward, making them high sensitive and readily incorporative into a rapid Point of Care device. This project will meet the best of the competences of the Experienced Researcher (ER) in all aspects of Organic Chemistry (high level expertize in classical Target Oriented Organic Synthesis and state-of-the-art synthetic methodologies including Diversity Oriented Synthesis, modern methods for activation of chemical processes, physicochemical methods of elucidation of the compounds structure) and BforCure expertise in the FASTGENE technology, Polymerase Chain Reaction and the microfluidic techniques. Through the present project, the ER will reach a level of maturity on several technological aspects but also on managerial and industrial aspects that will provide her new career perspectives. Following this new experience, the ER will be one step closer to act as a leader or manager of a research team.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Transatlantic fluxes of Saharan dust: changing climate through fertilising the ocean?' (DustTraffic).

assistant: **Concept**

Massive amounts of dust (~1 Billion Ton) are blown from the Sahara into and over the Atlantic Ocean every year. This dust strongly alters the atmosphere through blocking incoming solar radiation [cooling the atmosphere] and trapping outgoing heat that was reflected at the earth’s surface [warming the atmosphere]. In addition, aerosols carry huge amounts of metals and nutrients that can boost marine life, but also vast amounts of microbes, spores, and pathogens that are harmful for both marine- and terrestrial (including human!) life. The net effect of cooling/warming and ocean fertilisation/poisoning is presently far from understood as it depends on a complex set of parameters related to dust emission, dispersal, and deposition. In order to quantify these parameters, I propose to develop and apply a novel approach to study the transatlantic flux of Saharan dust and its environmental effect on the ocean by deploying a transect of seven ocean moorings with a dust-collecting surface buoy below the Saharan dust plume from NW Africa to the Caribbean. Sampling dust in air as well as under water at a biweekly resolution for initially one complete year will for the first time allow to: 1) quantify the seasonal variability in Saharan dust export into the Atlantic, 2) distinguish between high-altitude summer plumes versus low-level winter trade-wind transport, 3) quantify source-to-sink changes in particle size and the related (metal, nutrient, and biological-) composition of the dust, and 4) determine the in situ bio-availability of the associated nutrients and their potential fertilisation of the photic zone. These unique, seasonally and spatially resolved data will bridge the gap between the bi-weekly sediment-trap record off Cape Blanc (NW Africa, since '85) and the daily dus
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Knowledge intensive entrepreneurship in networks'.

assistant: **Concept**

University of Twente (UT) is profiling itself as the entrepreneurial University. From early 80's there is an active support of entrepreneurship for graduates entering the entrepreneurial path; start-up companies using UT-knowledge; and innovating regional, national and international operating companies (small and large) operating in networks. To guide research in this area we offer coaching and training to (Ph-D) students in a setting in which this broad view on high tech entrepreneurship in networks can be studied in theory and in practice. In the Dutch Institute for Knowledge Intensive Entrepreneurship we combine in a synergetic way four functions: research, teaching, consulting and training, and business development support. The mission is to combine thorough academic work with practical relevant work on entrepreneurship in network perspective. The academic research programme is leading in determining the scope of the work being done in the institute, but practical relevant projects add to the research by offering opportunities to gather empirical data. Our academic teaching programs are offered to university students as well as to practioners and researchers. Student enterprises and networks between students and entrepreneurs are stimulated. Entrepreneurial spin offs of academic research are encouraged, as University industry interaction is one of the main mechanisms for high tech entrepreneurship. The Dutch Institute for Knowledge Intensive Entrepreneurship offers fellowships to researchers interested in knowledge intensive entrepreneurship in networks. In our research we look at micro interaction patterns in networks of entrepreneurs and other actors leading to innovation and consequently change in economic structure on micro-meso and macro level.Our special inter
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Effect of a program of short bouts of exercise on bone health in adolescents involved in different sports' (PRO-BONE) under Seventh Framework.

assistant: **Objectives**

Osteoporosis is a common health problem associated with high morbidity, mortality and economic costs in older people, and prevention remains the most effective approach. Exercise is an evidence-based approach because of its impact on bone development, maintenance and strength but not all forms of exercise appear to strengthen bone. Further research is therefore needed to explore the role of short bouts of weight bearing exercise, that are acceptable to and feasible for adolescents, to supplement involvement in non-osteogenic activities. Plyometric jump training has been suggested as such exercise but the effects on adolescent bone health and associated metabolic processes have not been rigorously assessed.The aim of project PRO-BONE is to therefore longitudinally assess bone health and its metabolism in adolescents engaged in osteogenic (football) and non-osteogenic (cycling and swimming) sports and then examine the effect of a short and inexpensive plyometric jump training programme on these outcomes.Eighty-four male adolescents (12-14 yr) will be recruited as follows: footballers (n=24), cyclists (n=24), swimmers (n=24) and controls (n=12). Footballers, cyclists and swimmers will be randomly assigned in 2 subgroups (e.g.: intervention cyclists and control cyclists). Only intervention groups will perform the plyometric jump training [9 months, ~10 min/day, 3 to 4 times/ week (depending on progression)]. Body composition, fitness, nutrition, physical activity, anthropometry and serum bone turnover will be measured.The benefits are associated with PRO-BONE are: early detection of poor bone health, improved bone mineralization development during growth and contribution to Gracia-Marco’s development and integration at Exeter.Research will be hosted at the research-intensiv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Polymer Solvation with COSMO-RS', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

SCM is a scientific software company with a track record of over two decades of translating scientific advances into commercial success. The company’s strength has traditionally lied in electronic structure methods, its flagship product being the well-known ADF package. In recent years SCM has been broadening its scope to add approximate, faster methods. One of such methods is the COnductor-like Screening MOdel for Realistic Solvation, COSMO-RS, a powerful continuum solvation model.COSMO-RS is able to predict thermodynamic properties in solutions in an efficient and general way, and has proven to be one of the modules with the fastest-growing demand within SCM’s portfolio – the company’s revenues from COSMO-RS have increased almost 130% over the last two years. COSMO-RS is therefore a key component of SCM’s growth strategy.However, our COSMO-RS implementation has one important limitation, as it cannot deal with molecular models above a certain size. And the ability to predict thermodynamic properties in larger molecules, and in particular polymers, is of great relevance in many areas (e.g. food packaging, coating technology, membrane separation and drug development). SCM therefore plans to extend its COSMO-RS implementation to allow for molecular models of any size, in order to increase our market share in the field of polymer chemistry.There are several possible routes to accomplish that (such as fragment-based methods or equations of state (EOS) approaches) but they all require a level of expertise in thermodynamics and continuum models currently lacking within SCM. This is highly specialized work, which falls outside SCM’s strengths in electronic structure methods, and the company needs to recruit skills combining expertise in continuum solvation models as well as mo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Morphological responses and interactions of clonal marine macrophytes with their nutrient environment' (CLONMACMORPH) targeting Sixth Framework.

assistant: **Abstract**

Sea-grasses and meadow forming macro-algae are renowned for their high productivity. Knowledge of the dynamics and of these systems and what drives these is therefore crucial in understanding them. Sea-grass species all share a common architecture of clonal growth. Many seaweeds also possess this clonal integration, however, are usually ignored in this context. By differential or changing investments in below- or aboveground plant parts clonal plants are able to escape adverse conditions and rapidly colonise a new environment. In the marine realm, this strategy as a way to explore sediment nutrient resources is not clear.To more understand the dynamics of sea-grass and clonal macro-algal meadows this project aims to elucidate the influence of sediment and water nutrient resources on the architecture, ecophysiology and colonising potential of intertidal and sub-tidal sea-grasses and clonal seaweeds. Investigation will take place at two levels: a population level and a plant organismal level. The first level will include effects of sediment fertilisation on population structure and colonising capacity of species. Studies on the second level will include development and evaluation of indicators of plant stress (nutrient limitation, adverse temperature, etc.). This stud y can be of special importance in trying to understand and predict the recent clonal algal proliferations in the Mediterranean caused by species of the genus Caulerpa. Results of this study may indeed be used to develop and fine-tune management plans for coastal nature conservation.