RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'PRInted Symbiotic Materials as a dynamic platform for Living Tissues production' in the context of a Horizon Europe call.

assistant: **Objectives**

The PRISM-LT aims at creating a flexible platform for next generation living tissue manufacturing based on Hybrid Living Materials. We plan to design a novel bio-ink where stem cells are integrated in a support matrix enriched with engineered helper cells (either bacteria or yeasts, depending on the application and requirements). Tuning the operational parameters of the bioprinting process, we will cast down the material controlling the mechanical properties of each “voxel”, to get to a 3D patterned structure where stem cells are locally induced to initiate their differentiation towards different lineages. As far as stem cells proliferate, the helpers remain in a quiescent state. However, when the stem cells get stimulated by the local (printed) mechanics and enter a differentiation pathway, they start secreting a pool of lineage-specific metabolites. The helper cells are designed to sense these early markers of differentiation, and to respond by producing in-situ the corresponding growth factors, providing the relevant chemical guidance. Helper cells within the platform amplify the initial lineage commitment in each area and dynamically sustain differentiation on a longer term. During the project we will implement this strategy and develop two independent symbiotic materials, targeting biomedical and food applications, respectively.


**Keywords:** bioprinting
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'An e-Night to Remember' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Researchers’ Night events have been organised in Cyprus by the Research Promotion Foundation since 2006. With the e-Night project, the Research Promotion Foundation and its partners aim to organise yet another successful event in Cyprus that will contribute towards the public recognition of researchers and the development of a positive attitude from the younger generations regarding the researchers’ profession and its contribution to society. Cyprus participation in European research and especially the FP7 Thematic Priority 'Information and Communication Technologies' (ICT) has been traditionally the most popular amongst the Cyprus research community. In contrast, Cyprus population is lacking behind when it comes to usage of ICT compared to the rest of Europe’s population. In order to promote the ICT culture among the Cyprus public and especially young people, this years’ Researchers’ Night event in Cyprus will be dedicated to research in the ICT fields. The public will be given the opportunity to meet researchers, interact in a personal level and share experiences with them, in order to realise that researchers are ordinary people. Furthermore the visitors will get a grasp of the researchers’ job concerning ICT through a number of on-site and hands-on interactive activities and presentations. The activities will also include an award ceremony and be addressed to the large public, whichever their gender, age, social status or level of scientific training – politicians, public authorities, policy makers, enterprises, associations,  students. Activities will offer a broad range of diversity, adapted to each particular target, and they will be organised in a relaxed and festive context.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'High-speed timE Resolved fluorescence iMaging with no pilE-up diStortion', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The overarching goal of HÈRMES is to establish a new methodology for time-resolved imaging by means of Time-Correlated Single Photon Counting(TCSPC). Since its debut in the literature, the potential of TCSPC as non-invasive, ultra-sensitive and extremely precise imaging tool was manifest. Numerous applications have benefited from it so far, but a key limitation still prevents its wide use in many other crucial applications: the speed of a TCSPC acquisition chain must be kept low(few Mcount/s in the best case) to avoid distortion due to pile-up of events. Up to now researchers in this field have tried to work around this limit mainly by posing multiple channels in parallel, but still facing severe limitations mainly due to efficiency, fill factor, precision, linearity and readout complexity.I propose an innovative methodology for removing all constraints on TCSPC, promising a change in the paradigm of how TCSPC systems are conceived and how time-resolved measurements are carried out. To achieve such an ambitious goal, a radical change is necessary. I expect to develop a comprehensive mathematical model showing that pile-up distortion can be avoided with any combination of single photon detector and laser excitation power if additional picosecond-precision information on the status of system in each time bin is acquired at run-time. I will develop ultrafast electronics for Single Photon Avalanche Diodes to move from theory to the real experimental world. Moreover, I will empower the new constraint-less TCSPC by developing an innovative computational imaging framework, opening the way to the real-time acquisition of 4D images. Next-generation TCSPC systems based on the HÈRMES methodology will allow the exploitation of this powerful tool in crucial applications such as, for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Rare Earth Magnet Recovery for Environmental and Resource Protection'.

assistant: **Innovation**

The REMANENCE concept is to develop new and innovative processes for the recovery and recycling of rare earth (RE) containing neodymium iron boron magnets (NdFeB) from a range of waste electronic and electrical equipment (WEEE). Advanced sensing and mechanical separation techniques combined with innovative processes based on hydrogen decrepitation will recover the rare earth magnets in the WEEE. Significantly with the REMANENCE concept, the aim will be to recover material in a form that can easily re-enter the primary magnet manufacturing production route, so providing large energy savings and production costs.There is no existing process for the recovery of NdFeB magnets from waste streams and this highly valuable material is lost to land fill with no prospect of commercial recovery. The material recovered in the REMANENCE concept will have a substantial economic value, which considering current virgin material costs, is estimated to be €80-120 per kg. If fully implemented REMANENCE will provide a secondary source of materials for the EU, large enough to supply the entire EU bonded magnet manufacturing industry and a significant proportion of the EU’s high value sintered magnet production.REMANENCE brings together Europe’s leading experts in; sensing, disassembly, recycling technology and materials processing with a group of innovative SMEs in a multi-disciplinary project able to deliver significant technical advances. The key technical roles of the SMEs as either equipment manufacturers (CTECH, OPTI, ABI) or direct end users of the recovered materials (MAG) will focus the project towards commercial outputs that will result in excellent exploitation opportunities for the developed processes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Innovation in small capacity ammonia refrigeration plants' in the context of a Fifth Framework call.

assistant: **Objectives**

Proposed project will improve possibilities using ammonia as refrigerant in small refrigeration plants (cooling capacities below 75 kW). Phase out of HFC and (H) CFC's, according to the Kyoto protocol (1997) in European world wide, leads to a search for alternative refrigerants. Ammonia could be such an alternative, because it neither contributes to the Ozone Depleting Potential (ODP) nor to the Global Wimbling Potential (GWP). SME project partners Dresden Kühlanlagenbau, Compact and Silk Borg Varmepumpe go Koeleindustri, which are installers of small refrigeration plants, and therefore have close contact to this market. Want to be on the forefront of this process and therefore together with Red's demonstrate that ammonia is applicable in small refrigeration plants. Proposed project will give the She's the ability to design, manufacture, install and run small ammonia refrigeration plants, and thereby keep their market shares and secure the conditions on which the She's arebased. A number of prototypes for different applications will be installed in the market demonstrating that a co-operation of She's and Red's can give She's new markets shares and prepare them for the future with natural refrigerants.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Supramolecular Chemical Biology Modulation of Protein-Protein Interactions' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

This proposal aims to explore the combination of supramolecular chemistry with chemical biology. Supramolecular architectures are proposed for the modulation of protein-protein interactions. Two general themes are outlined; 1) supramolecular chemistry in the cell and 2) supramolecular multivalency. Supramolecular architectures are brought forward as excellent tools to control protein-protein interactions at the cellular level. Supramolecular elements, selectively attached to proteins, are outlined to control protein dimerization and localization. The introduction of different supramolecular elements, either in vitro or in vivo via specific labeling techniques, is part of the plan, including the introduction of supramolecular elements, whose interactions can be reversibly switched with light. With these systems, the temporal control over protein-protein interactions and protein localization can be addressed. Self-assembling multivalent architectures are proposed as optimal scaffolds and flexible systems for recognition and binding of cells. The assembly process of the supramolecular architecture will be steered via interplay with the characteristics of the cellular target and the environment, controlling size, shape and composition. This self-assembling multivalent platform will be applied to control or initiate interactions between different types of surfaces, such as cells, antigens and chips. The self-assembling scaffolds additionally provide an ideal platform to be combined with proteins, allowing the generation of ordered protein wires, with control over orientation and distances between proteins. The combination of supramolecular chemistry with chemical biology is envisioned to enable the modulation of protein-protein interactions and thus provide entries to this l
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Assembly and Self -Assembly at the Interface of Biology, Chemistry and Physics' to be submitted under Fifth Framework.

assistant: **Abstract**

Recent developments in nanoscience and the inspiration derived from molecular biology give rise to visions of nanoengineering aimed at manufacturing complex, heterogeneous nano-sized structures of well-controlled architecture and function. The attainment of this technological goal requires a better understanding of Assembly and Self Assembly (ASA) as encountered in biology, supramolecular chemistry and soft matter physics. Certain areas of ASA are by now well established as domains for interdisciplinary research. The well-recognized ASA topics include soluble amphiphiles and block copolymers, membranes and proteins. However, the scope of the field is much broader, ranging from virology to petroleum engineering. The development of interdisciplinary research concerning the full range of ASA problems was hampered by the weak overlap between the communities involved. The proposed conference aims to help overcome this obstacle by gathering leading representatives of the diverse communities involved in order to discuss the broader aspects of ASA.In particular, the conference will emphasize biological and biologically inspired systems. It will bring together molecular biologists, soft matter physicists and supramolecular chemists to discuss ASA topics varying from viral assembly to the use of ASA to control water flow in oil reservoirs. Sessions will be devoted to silk and fibers, the extracellular matrix and the cytoskeleton of living cells, pattern formation by cells, physics of DNA and gene therapy, biomineralization, assembly of neurons and nanomanipulation techniques. Both the program and the participants are carefully chosen to promote future developments in ASA. The invited speakers are world leaders in their respective domains, capable of presenting talks to a mixed au
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Les nouvelles formes de gestion publique de la deviance en Europe' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

L'objectif gÏnÏral de la recherche est d'apprÏhender les rÏponses auxbouleversements Ïconomiques et sociaux que l'Europe connat depuis prÍs devingt-cinq ans et qui ont pris la forme de nouveaux modes de gestion de laprÏcaritÏ et de la dÏviance. Une enqute comparative sera menÏe dans six paysde la CommunautÏ europÏenne (Allemagne, Belgique, France, Grande-Bretagne,Grce, Pays Bas). En un premier temps, il conviendra de repÏrer, dans chacund'entre eux, les nouvelles formes de dÏviances, les conditions de leurÏmergence, les traits propres ¹ chaque tradition nationale et les populationsqui leur correspondent. En un second temps, on observera les diffÏrents modesde gestion mis en oeuvre pour freiner les causes et obvier les effets. Ils'agira d'observer si les nouvelles formes de gestion de la prÏcaritÏ et de ladÏviance ne gÏnÏrent pas un glissement d'une gestion sociale ¹ une gestionpÏnale, si cette Ïvolution ne s'opre pas au sein mme des tchestraditionnellement dÏvolues aux travailleurs sociaux et si elles n'incombentpas ¹ des professions qui jusqu'alors n'Ïtaient pas censÏes les assumer. Enfin,¹ partir de problmes qui se posent dans chaque pays de manire quasi identiquemais dans des contextes sociaux et culturels diffÏrents, on voudrait contribuer¹ dÏfinir les conditions grce aux quelles les mesures administratives etpolitiques, en particulier celles qui Ïmaneraient des CommunautÏs europÏennes,peuvent produire tous leurs effets. A cet Ïgard, seule une enqute comparativeportant sur des terrains ou se donnent ¹ voir concrÏtement les nouvelles formesde gestion de la dÏviance peut permettre d'Ïtablir les conditionsdiffÏrentielles, sociales et nationales, pour que les politiques en ce domainepuissent avoir quelques chances de succÏs.Pour mener ¹ bien ce travail compara
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Strategic Energy Technology for Industry in Europe' to be submitted under Horizon Europe.

assistant: **Abstract**

The CSA Strategic Energy Technology for Industry in Europe (SET-IndEU) is responding to the call HORIZON-CL5-2022-D4-02-06, to propose a structured Secretariat for supporting and strengthening the activities and outcomes of the IWG6 on Energy Efficiency in Industry. The consortium will support the IWG6 to advance the monitoring and revision of the Action 6 Implementation Plan (IP) with the aim of reaching technology targets collectively across SET Plan countries making EU industry less energy, resource and emissions intensive and more competitive. For that purpose, the future needs of the process industry, the R&I targets, and the emerging policy priorities will all be taken into consideration by engaging the IWG6 stakeholders in key activities with industrial and research associations and fora, specifically strengthening the relations, dialogue and exchange with the other SET Plan IWGs and the ETIPs.


**Keywords:** SET Plan, Process Industry, Energy Efficiency, Energy Intensive, IWG6, Secretariat, Electrification
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Tracer Raman-Driven Mass Spectrometry Imaging (TRaMaSI): a new platform for on-tissue Tracing of Nutritional and Biochemical Trajectories' (TRaMaSI).

assistant: **Innovation**

Unlocking the mysteries surrounding nutrient fate within the human body has remained an enigmatic pursuit. Our organs and tissues crave specific nutrients, especially in physiological and pathological conditions. Yet, the intricate journey these nutrients embark upon within our bodies remains largely unclear. The aim of my ambitious project is thus to create an innovative chemical-spatial workflow capable of (1) providing the anatomical coordinates of nutrients of interest across tissues (and organs) and (2) understanding the biochemical route these nutrients undergo in the respective tissue areas of the target organ. For this, I will use a complementary approach relying on advanced techniques such as tracer metabolomics, mass spectrometry imaging (MSI) and Stimulated Raman spectroscopy (SRS). I will benchmark this technological platform onto a model of acute kidney injury (AKI) to identify and localize the predominant biochemical pathways. The amalgamation of SRS and MSI with tracer metabolomics is groundbreaking given the current technological landscape and provides an innovative and feasible solution to the posed challenge.


**Keywords:** tracer metabolomics, nutrient mapping, kidney
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Asymmetric Brønsted Acid Catalysed Cyclisation Reactions'.

assistant: **Concept**

We wish to develop new asymmetric Brønsted acid catalysed cyclisation reactions that will allow the efficient and highly enantioselective construction of azabicyclic structures from readily available starting materials. This will constitute a new, powerful and broadly applicable organocatalytic asymmetric strategy to such target molecules. Conceptually our proposal is to exploit the high reactivity of N-acyl iminium ions in cyclisation reactions within the asymmetric environment of an associated conjugate base of a chiral Brønsted acid (HA*). For enantioselective N-acyl iminium ion cyclisations, a keto amide starting material with a suitable pi-nucleophile attached to the nitrogen atom of the amide is required. The reaction is technically trivial to perform; a solution of the keto amide starting material is treated with a catalytic quantity of an ‘effective’ chiral Brønsted acid. Loss of water should result in the formation of an N-acyl iminium ion, which, in a low polarity solvent, should be (tight) ion paired with the chiral conjugate base of the Brønsted acid. Provided there is sufficient ordering and effective facial differentiation in the ion pair, attack of the pendant pi-nucleophile will give rise to enantioselectivity in the (irreversible) cyclisation step. During the course of the Fellowship, through physical organic chemistry techniques and molecular modelling calculations we would like to elucidate the mechanistic pathway and origins of stereocontrol in the new catalytic asymmetric methods we are developing. Finally we wish to apply the developed chemistry as a key carbon-carbon bond forming step in the total asymmetric synthesis of an indole alkaloid natural product. Therefore this multidisciplinary Fellowship project will involve the development of innovati