RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'An e-Health expert system for diagnosis and treatment of diabetics to reduce the risk of skin breakdown and co-existing foot diseases' to be submitted under Horizon 2020.

assistant: **Abstract**

VOXELCARE, is a Spanish software/hardware engineering company with 15 years experience in the design, production and marketing of industrial applications ranging from special purpose CAD/CAM systems, contact and non contact 2D and 3D (foot) scanning devices, CAD design software and CAM systems for different kind of machines (e.g milling), for the worldwide footcare and footwear industry. We have been working in the development of a disruptive way to improve the treatment of people with diabetes caused foot problems. To this end we aim to prototype, test and commercialise an eHealth expert system for diagnosis and treatment of diabetics and other added features to reduce the risk of skin breakdown and co-existing foot diseases. According to the World Health Organization, the number of people with diabetes grows worldwide and is projected to become one of the world’s main disablers and killers within the next twenty-five years. In 2014, 422 million people in the world had diabetes and caused at least $612 billion in health expenditure worldwide. The diabetic foot or diabetic foot syndrome (DFS) and diabetic foot ulcers (DFU) is one of the most feared diseases resulting from diabetes mellitus. Ultimately affecting some 25% of those living with the disease. One important preventive measure is to wear therapeutic footwear in the form of diabetic orthotics. The goal of this project is to improve the cloud based tools in the current VOXELCARE online CAD/CAM system so that it is possible to create an e-Health framework for footcare, and allow practitioners in developed countries to help less skilled practitioners in emerging economies that similar levels of treatment quality can be achieved worldwide. On the other end, this technology will also improve the capability of footcar
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Open Innovation – Research Translation and Applied Knowledge Exchange in Practice through University-Industry-Cooperation' under Horizon 2020.

assistant: **Concept**

The overarching objective of OPEN-INNO-Train is to form an international and inter-sectoral network of organisations collaboratively working on the joint research field of Open Innovation, University-Industry Cooperation and Research Translation. To facilitate Knowledge Development and Sharing in four contemporary areas - FinTech, Industry 4.0, CleanTech, FoodTech. For globally interconnected societies, scientific research has the potential to foster yet unrealised economic growth, competitiveness, and wellbeing. The conversion of research outputs into tangible outcomes, and, ultimately, sustainable impact is critically important and needs optimising.The process of converting research findings into economic and social benefits appears increasingly complex at a time when researchers often work in multidisciplinary teams, in a context of Open Innovation when cooperating with industry and other stakeholders. Illuminating it from the perspective of Research Translation, an approach increasingly gaining traction in the specific setting of University-Industry Collaboration, OPEN-INNO-TRAIN aims at opening the black box of knowledge conversion processes to generate and apply new insights from those four industry areas. Furthermore, OPEN-INNO-TRAIN encapsulates the development of robust Research Translation tools capable of facilitating the translation process of multidisciplinary research findings for the generation of impact. Combining scientific excellence from European and international universities, Research and Technology Organisations with hands on expertise from pioneering companies, OPEN-INNO-TRAIN will spearhead this sustainable venture using digital innovation hubs, co-tutelle, industrial PhDs, PPPs and training measures to encourage international cooperation among r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'A natural solution for post-harvest protection of fruits and vegetables' to be submitted under Horizon 2020.

assistant: **Abstract**

45% of fruits and vegetables are lost globally; food waste has massive economic, social, and environmental impacts. Post-harvest losses amount to more than €200 billion globally and has a global carbon footprint of 3.3 GtCO2 eq. per year according to the Food and Agriculture Organization (FAO). If food loss was a country, it would be the third largest emitting country in the world.80% of these losses are due to fungal contaminations. Farmers lack natural solutions to tackle this issue and rely almost exclusively on chemical products that are gradually being banned by regulations since they raise health and environmental concerns.Antoferine, based on a patented disruptive chemical-free extraction process, is a natural vine extract that contains polyphenols, a potent natural fungicide and antioxidant. It presents itself as a very attractive natural solution for post-harvest protection in agriculture.Antofénol is a French biotechnology SME founded in 2014 and dedicated to the development of biocontrol products from natural substances. To date,Antofénol’s highly skilled team consists of 9 engineers, scientists and business executives with a background in biotech engineering, biochemistry, agronomy and business development.On the back of 5 years of R&D, industrial development and successful field-testing results, Antonfénol’s innovation has reached TRL 8.  Over the next 24 months we will 1/ scale-up our extraction process, 2/ optimise Antoferine's marketable formulation and 3/ request the homologation of the active ingredients. The company is therefore soliciting a blended finance package of €3.56m (€2.06m grant/ €1.5m equity) through the EIC Accelerator program.  We project a turnover of €26.7m and an Ebitda of €12.9m by 2025 propelled by Antoférine. Our headcount will incr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Novel Techniques for Describing Shapes in Computer Graphics and Image Processing'.

assistant: **Concept**

Image informatics is a key technology for realising the information society. It comprises both image synthesis (computer graphics) and image analysis (image processing). The common way to describe images and shapes is by means of pixels (for image analysis) and triangles (for image synthesis). These descriptions have their inherent shortcomings. Due to technological developments (Moore's Law) the geometrical models are becoming so large that these shortcomings become inadmissible. Therefore we aim at a significant enhancement of traditional shape description methods based on a semantically higher-level geometric description language. Image informatics is a key technology for realising the information society. It comprises both image synthesis (computer graphics) and image analysis (image processing). The common way to describe images and shapes is by means of pixels (for image analysis) and triangles (for image synthesis). These descriptions have their inherent shortcomings. Due to technological developments (Moore's Law) the geometrical models are becoming so large that these shortcomings become inadmissible. Therefore we aim at a significant enhancement of traditional shape description methods based on a semantically higher-level geometric description language.DESCRIPTION OF WORKMathematical conceptions of homotopy and Morse theory might be useful to overcome the barriers of existing shape description techniques. Preliminary investigations carried out by e.g. T. Kunii in Japan show promising results. We will bring together a number of competent European researchers, we will consult Kunii and get early results (working demonstrators) to assure industrial interest. On basis of the results obtained in this twelve month project, it will be decided whether these new and no
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Full biomechanical characterization of the coronary atherosclerotic plaque: biomechanics meets imaging' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Myocardial infarction is responsible for nearly 40% of the mortality in the western world and is mainly triggered by rupture of vulnerable atherosclerotic plaques in the coronary arteries. Biomechanical parameters play a major role in the generation and rupture of vulnerable plaques. I was the first to show the relationship between shear stress – one of the biomechanical parameters - and plaque formation in human coronary arteries in vivo. This accomplishment was achieved by the development of a new 3D reconstruction technique for (human) coronary arteries in vivo. This reconstruction technique allowed assessment of shear stress by computational fluid dynamics and thereby opened new avenues for serial studies on the role of biomechanical parameters in cardiovascular disease. However, these reconstructions lack information on the vessel wall composition, which is essential for stress computations in the vessel wall. Recent developments in intravascular image technologies allow visualization of one or more of the different plaque components. Therefore, advances in image fusion are required to merge the different plaque components into one single 3D vulnerable plaque reconstruction. I will go beyond the state-of-the art in image based modeling by developing novel technology to 3D reconstruct coronary lumen and vessel wall, including plaque composition and assess biomechanical tissue properties allowing for full biomechanical characterization (shear stress and wall stress) of the coronary plaque. The developed technology will be applied to study 1) vulnerable plaque progression, destabilization and rupture, to improve identification of risk on myocardial infarction and 2) predicting treatment outcome of stent implantation by simulating stent deployment, thereby opening a wh
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Predicting the benefits of landscape restoration - a planning perspective formetapopulation models' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Research objectives and content Metapopulations are assemblages of local populations linked by occasional dispersal, and are widely recognised as important in the long-term persistence of many species. An important application of metapopulation theory is in the conservation of species in fragmenting landscapes. The metapopulation framework, applied at the landscape level, will enable us to investigate the best methods of preserving populations and species diversity in the current agricultural landscape, and to predict the benefits of investments in landscape restoration/rehabilitation. Butterflies are one of the best studied groups regarding the effects of habitat fragmentation, and have been widely used in theoretical metapopulation models. A range of butterfly species will be investigated in this project, using mark-release- recapture studies, distribution/occupancy surveys and experimental manipulation of populations. The results will enable us to look at the ways in which butterflies move through the landscape. Metapopulation models will be linked to movement models and to GIS. The models developed during this project will be valuable in testing the impact of different landscape change scenarios. Training content (objective, benefit and expected impact) The main training component of the project will be in GIS, which is a valuable tool in any study of spatially structured populations. GIS-based models will allow us to identify characteristics of the landscape which increase or obstruct butterfly movements at the landscape scale.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Next-Generation of Interior models of (Exo)planets:Studying the interior structure of giant planets and its effect on their evolution, atmospheres and observations' under Horizon Europe.

assistant: **Concept**

The prevalence of metals in exoplanet atmospheres is considered an important tracer of the formation of gas giants. However, the current theoretical framework is founded on the critical assumption that such planets are composed of a core surrounded by a homogeneous and well-mixed envelope. Recent data from Cassini and Juno show differently, resulting in a paradigm shift in the interiors of Jupiter and Saturn. Jupiter's envelope is now shown to be non-homogeneous, leading to new pathways for studying the interactions between giant planet interiors with their atmospheric constituents. This new knowledge desperately needs to be incorporated in exoplanet studies. This is the aim of N-GINE.We are in a unique time for this study. We have extraordinary data to study the giants in the solar system, and the JWST will provide exceptional data on exoplanets’ atmospheres. Now is the time to gather the stunning amount of exoplanet data and the detailed insights supplied by our solar system and get integrated knowledge coming from all giant planets.I have unique expertise in these fields to fill this gap and lead a team of 3 PhD students and 2 postdocs to work at the frontier of exoplanets and solar system science. We will provide the community with the first open-source retrieval tool for exoplanet interiors based on my state-of-the-art models for Jupiter, use JWST to compile the first database on refractory species in exoplanet atmospheres (indicating the solids accreted during formation), study atmosphere-interior interactions with self-consistent atmospheric radiative transfer and interior models, and go beyond the state-of-the-art with new interior models for Jupiter, Saturn, Uranus and Neptune with non-homogenous interiors and using Neural Networks. The impact of the new interi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'An integrated model of LEAN production concepts, practices, and climate as a tool for improving efficiency and effectiveness in hospitals and R&D units' (LEAN).

assistant: **Innovation**

In order to survive, organizations need to keep high efficiency and effectiveness by targeting the right quantity, at the right quality, at the right time, and in the right place. Lean production seeks to identify and eliminate wasted time, effort, and resources, leaving only streamlined processes that add value at every step. For example, by reducing protective buffer inventories, and improving the organizations’ capacity to ameliorate the potential damaging effects of variability in supply, processing time, or demand. Lean production has been implemented in many industries and has been proved highly successful in improving organizational processes, efficiency, and effectiveness. Recently, Lean has been implemented in two unique contexts; hospitals and Research and Developments departments. Both contexts are characterized by the need to balance on the one side innovation and be creativity, while on the other side, the need to standardize processes to keep high efficiency and effectiveness. Hospitals have started to implement Lean practices in order to improve their efficiency and quality of care. However, there are mixed results regarding their success to improve processes and in some cases, there are even reports of negative effects such as higher costs and more treatment errors. In the context of R&D departments, there is a tension between on the one side the need to innovate and be creative while at the same time adhere to Lean practices as standardization and minimum variation. The proposed network aims to develop better understanding of Lean production implementation in hospitals and R&D units, and specifically, identify conditions that explain why and how Lean production would have a positive effect on hospital and R&D units’ efficiency, quality, and potential fo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Computational Studies of Proton Dynamics in Hydrogen Bonded Systems and Enzymes'.

assistant: **Concept**

The main purpose of this computational research is to improve the understanding of biocatalysis and receptor triggering by studying the quantum nature of nuclear motion in proteins. Specifically, the research will be focused on three particular biological systems: Soybean lipoxygenase (SLO–1), Monoamine oxidase B (MAO B) and histamine H2 receptor (hisH2). The proposed studies will be devoted to the simulation of proton dynamics and proton transfer in systems containing short H–bonds, which are among the crucial factors for the functionality of enzymes, aimed at uncovering the relationship between the structure and the role of mentioned proteins. The work on SLO–1 should help understand and predict temperature dependence of its exceptionally large H/D kinetic isotope effect of about 80, and to clarify effects of point mutations on its activity. The research on MAO B should elucidate mechanisms of its reactive step and inhibition in the catecholamine dopamine metabolism in the central nervous system, related to the pharmacotherapy of Parkinson disease, depression and age–related cognitive disorders. By using receptor deuteration, the work on hisH2 should unlock the secrets of receptor's distinction between agonists and antagonists binding, which is of major relevance for pharmaceutical industry and drug design. Overall, it is intended to generally identify ubiquitous trends and features that are applicable well beyond the scopes of these individual investigations. During the project the researcher will acquire state–of–the–art methods of computational biochemistry. This represents a major career development as he will be able to later carry on with this leading–edge research in many directions, propelling his scientific independence and maturity. This will lay ground for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Regulatory networks underpinning fertility of the lateral florets on the barley inflorescence (spike)' in the context of a Seventh Framework call.

assistant: **Objectives**

The ancestral form of cultivated barley produces two rows of grain along the grain bearing 'spike'.  However, types with six rows of grain emerged soon after the domestication of the species and quickly became the dominant form in primitive agricultural systems.  This morphological and developmental switch is generally accepted to result from recessive mutations in a single gene called SIX-ROWED SPIKE 1 (VRS1).  However alleles at several other SIX-ROWED SPIKE genes have since been identified and shown to interact with VRS1 to enhance the six-row phenotype.  The appearance of six-rowed types provided a major yield enhancement in early agriculture and although the gap between two- vs. six. row types has narrowed through breeding, it is clear that considerable potential remains for exploiting the development of up to three times as many grains per inflorescence as a route towards increasing yield.  In this project I will take a novel approach in a crop plant to understand how this switch is elaborated.  I propose using Laser-Capture Microdissection of the group of cells that initiate the development of fertile lateral florets, coupled with RNA-seq of the resulting tiny RNA samples.  I will compare the obtained transcript profiles over developmental time from a pair of nearly isogenic lines that differ only for VRS1 (i.e. Vrs1/vrs1), thus avoiding any genetic background noise.  I will use the comparative data to identify differentially expressed genes and the time series data to investigate the network of interactions that promote this characteristic switch between infertile and fertile inflorescence.  Finally, I will initiate the production of transgenic knockdown plants to explore the functional effects of some of the identified genes on inflorescence development.  In th