RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Deep-Red/NIR Multi-Resonance Delayed Fluorescence Emitters for Efficient OLEDs'.

assistant: **Innovation**

Multiple-resonance (MR) thermally activated delayed fluorescence (TADF) materials are the current research hotspot in organic light-emitting diodes (OLEDs) due to their ability to deliver remarkable color purity with full-width-at-half maximum (FWHM < 30 nm) and high efficiency. However, emission of the majority of reported MR-TADF emitters fell in the blue/green region because of their intrinsic triangulene geometry and limited scope for structural diversity,  while examples of emitters addressing the other primary colors required for displays are either rarely (red) or not (Near-Infra Red (NIR)) reported. In addition, most MR-TADF OLEDs show severe efficiency roll-off and poor operational stability. Therefore, it is urgent need to make the new molecular designs for producing long-wavelength (> 600 nm) MR-TADF emitters i.e. pure-red/NIR MR-TADF emitters without compromising the emission color purity (FWHM < 25 nm) and efficiency roll-off of OLEDs. These materials are not only applicable in OLEDs, but also useful in night vision displays, sensors and information-secured displays. To this end, here we proposed two new MR-TADF emitter designs to circumvent the aforementioned drawbacks. In the first approach, we have designed linearly π-extended boron (B)/Nitrogen (N)-based polyaromatic hydrocarbon (PAHs) for shifting the emission into deep-red region. In the second approach, we have proposed a simple, yet versatile design for constructing narrowband NIR emitters. The rationality of the proposed designs were validated by the preliminary computational studies. This is a highly interdisciplinary project that covers the fields of organic synthesis, computational modelling, physical and optoelectronic characterization, OLED  fabrication and testing. This proposal exploits the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Architecture, Colonialism and Labour.  The role and legacy of mass labour in the design, planning and construction of Public Works in former African territories under Portuguese colonial rule' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The discipline of architecture, when dealing with Public Works associated with colonialism and territorial occupation, still focuses on the analysis of the constitution of the design teams, of the colonial Public Works offices, of the architects and engineers themselves. This focus on the designing elite misses a critical input to these Public Works, namely the Labour force responsible for realising these structures. As such, critical questions about the labour force engaged in the spatialization of architectural plans are still missing: who were those workers? What ethnic groups did they come from? How did they emerge in contingents that could aggregate a few thousand individuals? What was their recruitment like? What expectations did they have? How were they paid? What training did they receive? What repercussions did these (mostly compulsive) work experiences have? What conflicts did they provoke in colonial societies? How did they resist recruitment? How did they collaborate? How to deal with this legacy? In answer, ArchLabour will develop a new theoretical framework for assessing mass labour in order to shine a spotlight on these invisible workers, thus establishing a connection between historical subalternity and the inequality that still haunts communities inheriting this past. Through the study of the diverse colonial experiences of the African countries that have Portuguese as one of their official languages (Cape Verde, Guinea-Bissau, So Tom and Principe, Angola and Mozambique), and covering a wide period from the modern colonization that begins after the Berlin Conference through the industrial capitalisms exploitation praxis up to the years immediately following African independence, the project will cross the history of colonial architecture and the subject
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Manufacturing systems design and simulation' to be submitted under Fourth Framework.

assistant: **Abstract**

The proposal aims at supporting the establishment of a new department at the University of Patras, named Industrial Manufacturing. The applicant will assist these activities with his theoretical knowledge and practical experience in manufacturing systems design and simulation. Strong links to industry are considered essential for this new department. They will direct research activities and provide real world cases for research and teaching. The applicant will seek to establish such links by offering his expertise as a service to local enterprises. The applicant will: - support the definition of curricula - establish links to industry and to other academic institutions active in related fields - give lectures on manufacturing systems design and simulation - assist in the supervision of students and PhD students. MARION will produce the following results: - recommendations for curricula - a specification of a demonstration centre - - implemented manufacturing systems design and simulation software in this demonstration centre - lecture notes and training material for manufacturing system design and simulation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Spatial non-market VAluation for Biodiversity policy' (SVAB), addressing dissemination and exploitation.

assistant: **Impact**

Biodiversity policy is a fundamental component for sustainable development and actions to mitigate and adapt to climate change. For efficient and effective policy implementation it is crucial to understand where policy interventions can generate greatest ecological and socio-economic benefits. However, accurate spatial information about public good values of biodiversity is missing. The Spatial non-market VAluation for Biodiversity (SVAB) project aims to address this gap through four objectives. It will: 1) develop a novel spatially explicit survey valuation methodology to improve the accuracy of non-market valuation of biodiversity; 2) develop a spatial sampling methodology to improve the efficiency of sampling in spatial valuation surveys; 3) use these methodologies to assess the non-market values associated with nature restoration and extension of the nature protected areas network (Natura 2000) in the Czech Republic; 4) engage with policy-makers and citizens to enhance the relevance of the methods and outcomes and inform decision making in policy and public spheres.  SVAB will develop an individualised choice maps approach for stated preference research that enables testing the impacts of a wide set of spatial factors on public preferences for policy changes, test a spatial sampling strategy that will decrease survey costs in valuation and broader research, and improve the reliability of biodiversity valuation to inform spatial targeting of biodiversity policy. SVAB will enable the applicant to innovate spatial non-market valuation methods, develop new analytical and transferable skills, create new knowledge on societal benefits of nature, and publish the excellent research in leading journals in order to become an independent researcher. The project is highly inter
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'IN-LINE CRACK DETECTION IN SMALL DIAMETER PIPELINES' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

Crack-like defects such as, for example, stress corrosion cracks (SCC) or fatigue cracks represent the most dangerous defects in pipelines which can lead to failures with potentially catastrophic impact on man and environment. In line inspection tools for crack detection are currently not available for pipeline diameters <= 20. The aim of the project is to demonstrate the feasibility of reliable inline crack detection in small diameter pipelines in an operating pipeline using ultrasound-based intelligent pigging. In addition, the proposed technology can be used to replace hydrostatic retesting as a means of integrity testing. This will enable pipeline operators to increase the safety of their lines as well as to reduce the costs of integrity testing.Following the design and development phase a 12" prototype tool will be set up and extensively tested using a test pipeline. After that the performance of the tool will be demonstrated in a real 12" crude oil pipeline. Based on the already available experience with ultrasonic crack detection in large diameter pipelines the following outcomes of the project are expected :- innovation in the field of both ultrasonic electronics and data processing hardware.- Availability of a prototype tool for crack detection in small diameter pipelines (diameters from 10" to 16")- demonstration of reliable in-line crack detection in an operating 12" crude oil pipeline.Pipeline systems are a considerable component of the world energy supply system and usually ensure a safe and, from an environmental point of view, acceptable means of transport for liquid and gaseous hydrocarbons.The integrity of a pipeline, however, can be severly damaged in the course of its design life e.g. by corrosion or cracking. In the event of damage, for example leaka
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'International Fellowship Program on Materials & Matter, Energy & Environment, Human Health & Life-Sciences, and Accelerator Technology' to be submitted under Seventh Framework.

assistant: **Abstract**

Paul Scherrer Institut (PSI) proposes to create a new “bottom-up driven” post-doctoral programme, PSI-FELLOW, to enable individual experienced researchers to pursue their research career at one of our internationally recognized research departments.PSI is active in condensed matter physics, materials sciences, particle physics, life sciences and medicine, nuclear and non-nuclear energy research and energy-related ecology. The fellows will benefit from the outstanding research infrastructures, including access to world-leading large-scale facilities such as the Swiss Light Source (SLS), the Spallation Neutron Source (SINQ), the Swiss Muon Source (SμS) or the proton accelerator, to name the largest facilities. In addition, PSI operates the nationwide only laboratory for handling highly radioactive samples (Hot Laboratory). The fellows will perform science in a multi-disciplinary research center and being supported by world class scientists seeking long-term solutions for central problems of society, economy and industry.PSI-FELLOW will host in total 48 incoming and 12 re-integration fellows over the project period of 60 months. The duration of each individual fellowship will be 24 months. In addition to the highly innovative scientific environment, PSI offers great opportunities for continuous education and training in areas such as project management, presentation-techniques and improvement of language skills, etc. The combination of the scientific qualifications with managerial skills will strengthen the career opportunities of the experienced scientists in academia or the private sector.The broad spectrum of research areas and the outstanding research infrastructures make PSI particularly suitable for the implementation of PSI-FELLOW which will contribute to sustainabl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Nanomaterials in Oncology: Exploiting the Intrinsic Cancer-Specific Toxicity of Nanoparticles.' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

In our current society, therapeutic strategies against cancer suffer from dose-limiting toxicity, lack of specificity and high morbidity. To overcome this, the use of nanomaterials (NMs) is rising, where several NM formulations are undergoing clinical trials or are used in clinics where the NMs are used as drug delivery vehicles or as mediators in physical anticancer methods (e.g. hyperthermia), where to date, the success rate is limited due to low tumor targeting efficacy, lack of specificity and frequent re-use of classical toxicity mechanisms.To overcome these issues, this research program aims to exploit the intrinsic toxicity of certain types of metal-based, degradation-prone NMs (Fe-doped ZnO, Fe-doped CuO and Ag of different sizes and coatings) towards only cancer cells as a novel and generic anti-cancer tool with 1) improved efficacy against difficult to treat cancers such as multidrug-resistant cancer cells, 2) enhanced specificity and selectivity of the treatment by the intrinsic cancer cell-specific toxicity of NMs towards cancer cells. To overcome the issues related to selective delivery of the NMs, tumor-homing cells will be used that have been shown to efficiently home to primary tumors and their metastases. In practice, the NMs used show distinct degradation kinetics that primarily induce cancer-selective toxicity. To obtain efficient tumor targeting, suicide gene-expressing tumor-homing cells will be loaded with the NMs in their cytoplasm, hereby impeding premature NM degradation. The tumor homing efficacy of these cells will be monitored via optical imaging and once at the target site these cells will be chemically destroyed using the suicide gene strategy. This will release the NMs into the tumor site, where they can selectively destroy the cancer cell
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Sustainable soil management to unleash soil biodiversity potential and increase environmental, economic and social wellbeing.' under Horizon 2020.

assistant: **Concept**

SOILGUARD envisages a future where the conservation of soil biodiversity and the environmental, economic and social wellbeing of EU biogeographical regions is guaranteed. Unsustainable management and climate change are increasing land degradation and threatening soil biodiversity. Urgent action is required to mainstream sustainable soil management practices and the perception of soil biodiversity as a key nature-based solution to face land degradation and climate change stressors. The efficacy of this call to action depends on addressing major knowledge gaps related to biodiversity and soil-mediated ecosystem services. Soil biodiversity assessment emerges as a key challenge to be overcome. SOILGUARD will co-create a conceptual and analytical framework with the potential to become the global standard for future assessments of soil biodiversity status and its contribution to soil multifunctionality and human wellbeing. This framework will be validated in an innovative experimental design, combining multiple study sites across biomes and regional land degradation gradients with in-situ climate change simulations. Thus, creating the evidence to fill the gaps of knowledge and quantify the environmental, economic and social consequences of unsustainable soil management. All knowledge co-created will be shared through SOILGUARDIANS, a predictive tool based on the causal links between soil biodiversity, soil multifunctionality and wellbeing to support stakeholders on the transition to sustainable management. The SOILGUARD’s network of knowledge and the connectivity enabled by SOILGUARDIANS app will create an ecosystem of innovation for users to showcase, learn and share experiences. SOILGUARD will co-create evidence-based conservation recommendations for policies and frameworks
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Infrastructure for transnational access and discovery in structural biology' (2014-2020).

assistant: **Concept**

Structural biology reveals the molecular architecture of life; the three-dimensional structure of biomolecules and how they interact to form complex machineries and cells. Structural biology is key to innovations in chemistry, biotechnology and medicine: new drugs, advanced vaccines, novel biomaterials, engineered enzymes for food production, a cleaner environment, and efficient biofuels. iNEXT-Discovery takes on the challenge of proactively supporting the uptake of existing tools, and the innovation of new tools, to promote scientific Discovery and translation in a range of disciplines, building on the success of the H2020 project iNEXT (infrastructure for NMR, EM and X-rays for Translational research).iNEXT-Discovery brings together a strong network of leading structural biology facilities in partnership with regional experts and ESFRI communities in medicinal chemistry, translational medicine, biological imaging, and food research, to disseminate knowledge and services. We aim to stimulate the wider uptake of structural biology across Europe, across scientific disciplines and research sectors. Significant hardware and software advances allow targeting transnational access to advanced instrumentation also to scientists without previous expertise in structural biology: uptake will be facilitated by training and thematic calls focused on new communities. Access to our instrumentation and expertise will ultimately allow European scientists to gain structural insight that can translate into innovations in the biomedical, food, biotechnological and biomaterials sectors. Our joint research activities will roll-out advances in key technologies for translational research: fragment screening for drug development, EM efficiency and capacity, NMR applications to extend structure
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Identification of genes and pathways regulated by the HAT activity of MOZ' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The research programme will comprise the study of the Histone acetyl transferase (HAT) MOZ (Monocytic leukaemia Zinc finger) a critical player in the development and maintenance of the haematopoietic system. In addition, translocations of MOZ are associated with Acute Myeloblastic Leukaemia. Given the importance of this protein in haematopoiesis and leukaemogenesis, it would be essential to further understand the function of MOZ and in particular to identify the genes regulated by its HAT activity of MOZ. A mouse line specifically mutated to abrogate the HAT enzymatic activity of MOZ has been developed in the host laboratory, and represents a powerful and unique tool for the study of MOZ HAT activity. Using Chromatin ImmunoPrecipitation followed by sequencing (ChIP-seq), genome wide targets of MOZ will be determined and the consequences of the deletion of its HAT activity on the epigenetic landscape will be investigated through the survey of several histone modifications and RNA polymerase II recruitment. The non-histone targets of MOZ will be identified through the SILAC technique. Finally a MOZ murine leukaemic model has been developed, based on the transduction of bone marrow cells with a retrovirus encoding MOZ-TIF2, one of the fusion proteins involving MOZ. ChIP-seq will be performed in these leukaemic cells to identify genes targeted by MOZ-TIF2 and changes in epigenetic marks at these loci. Overall, this project will provide a better understanding of MOZ HAT activity in haematopoiesis and leukaemogenesis. Crucially, this project will enable Dr Anne Largeot to obtain and develop a wide range of new and transferable skills through a variety of multidisciplinary training programs. Relying on the knowledge and expertise of her supervisor and the exceptionally high ca