RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Enhancing collaboration in research for  Livestock' (RTD2FARM).

assistant: **Innovation**

RTD2Farm has a simple, yet effective strategy to increase the uptake of RTD Results by livestock farmers.RTD2Farm will be involving the three main players of the process; RTD providers (Research centres, Universities, Industry, etc), Technology Transfer experts (Networking and Training Organisations) and Farmers (End Users).RTD2Farm will analyse methods for knowledge and technology transfer, define Best Practice, and spread these. RTD2Farm has concentrated on pig farms, as they are the main animal for meat production in the EU. The process to optimise Knowledge and Technology Transfer should be transferable to other species, as the main Technologies are similar: Feed, Genetics/Breeding and Farm Management. Obviously there will be differences in the technologies, but the Knowledge and technology Transfer methods will be similar.Three regions have been selected to represent the diversity of Livestock farming Regions in the EU. Benelux has a similar “farm landscape” (farm size and production techniques), covers a small area and has a high uptake of new knowledge and technologies (K&T). Austria has a very diverse farming landscape; with a very diverse uptake of K&T. Italy has more small farms where dissemination of K&T is especially challenging.These three landscapes are a representative majority of the EU wide situation.  Industry Partners will be especially keen to take these new K&T Transfer methods into their most important developing markets in the Newer Member States and beyond.  A main goal of RTD2Farm is to develop Best Practice methods for a variety of K&T Transfer scenarios..K&T Transfer from Universities has the air of being inefficient. Of course K&T Transfer by Industry is more efficient, as the research itself is very consumers oriented. The difference in the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Plastic Degradation by Genetic Engineered Black Soldier Fly using Chitosan Nanocapsules'.

assistant: **Innovation**

The management of plastics, a persistent environmental challenge due to their durability, necessitates innovative solutions. While Black Soldier Fly (BSF) larvae demonstrate potential as a bioremediation agent for organic waste, their capacity for plastic degradation remains limited. This study proposes enhancing the plasticolytic capabilities of BSF larvae through genetic engineering, specifically by introducing plastic-degrading enzymes using CRISPR/Cas9 technology. To overcome the challenges associated with low gene delivery efficiency in insects, we propose employing chitosan-based nanocarriers. These carriers offer biocompatibility, biodegradability, and protection for genetic material. Integrating magnetic nanoparticles into these carriers enables magnetofection, improving gene delivery precision and efficacy. By genetically modifying BSF larvae to degrade plastics, we aim to develop a sustainable, eco-friendly approach to plastic waste management, reducing reliance on harmful chemicals and minimizing environmental impact. This research has the potential to expand beyond conventional plastics, contributing to comprehensive waste management strategies.


**Keywords:** Chitosan nanoparticles, Plastic degradation, Black Soldier Fly
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Advanced study of the atmospheric flow Integrating REal climate conditions to enhance wind farm and wind turbine power production and increase components durability' in the context of a Horizon Europe call.

assistant: **Objectives**

To deliver the future needed renewable energy capacity, wind farm developers will have to use larger turbines, at higher altitudes, explore novel geographical regions and offshore sites. Currently, wind turbines and wind farms are designed and operated considering “just” wind conditions. Consequently, the models do not take into account the physics and aerodynamics of atmospheric wind flows at high altitudes, neither how this is affected by the location, the effect of precipitation and/or sand. This reduces the expected efficiency of wind energy production, and makes hard to estimate the energy outputs, operating costs and lifespan of blades and turbines, increasing variability and the risk to investors and project developers when designing wind farms, reducing the total potential investment. Unless new sites can be identified and designed optimally, the LCOEs will start to rise as developers have to design wind farms that cannot be well predicted with conventional models.The AIRE consortium foresees precipitation and other events (clouds, sand, shear, inflow) that wind brings into the state of play to be the new key parameters for siting of wind turbines, wind farm design, component design and O&M strategies planning. AIRE will investigate solution to assess the potential impact of REAL climate conditions in different terrains, and different altitudes both onshore and offshore, gathering information from 4 experimental sites and 4 commercial wind farms.Specially AIRE will bring together researchers, blade manufacturers and utilities to create an open access knowledge hub of experimental data, develop new numerical models, build tools to design and control wind turbines and wind farms. The effectiveness of the developed tools and models will be validated using data from
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Creating an Agenda for Research ON Transportation sEcuity' to be submitted under Seventh Framework.

assistant: **Abstract**

Easy, efficient, safe and secure transportation is a core factor for European growth, collaboration and employment and therefor an item in the Europe 2020 strategy. Land transportation has two main challenges concerning security: avoiding interrupts of transport itself to assure the flow of freight and passengers to guarantee supply of the population and avoiding that transportation modes themselves become a mean for attacks. The future research agenda for security in land transport which CARONTE will provide, focuses on core relevant gaps caused by emerging risks and will avoid doubling in research. For this CARONTE will provide answers to the question of what type of security related projects should be planned in the future, considering the current state of the art and existing research projects. It will cover all threats (including cyber-crime) and security aspects for all land transportation modes, respecting fundamental human rights and privacy.  The step by step method includes analyzing the state of the art and emerging risks, identification of gaps, analyses and assessments of potential solutions and the research agenda.The CARONTE consortium consists of universities and research institutes, providing well experiences (research and consultancy) in transportation, logistics, infrastructure management and security. The partners are aware of practical needs and frames in land transport, and security as well as ethic, social and privacy aspects. As the partners come from neutral organizations, remaining neutrality concerning the project findings is guaranteed. Results which may mainly cover private interests are prohibited. This leads to a balanced  and efficient research agenda. To ensure practical use and acceptance of the final recommendations, end-users (transpo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'A Novel Understanding of Pandemic Disease in Preindustrial Europe (1300-1800): Combining History, Machine Learning and Natural Sciences' under Horizon Europe.

assistant: **Concept**

Born from years of interdisciplinary collaboration, EUROpest aims to articulate the complex ways in which social-ecological systems  shape epidemics. It builds on resilience and actor-network theories to advance its own eco-bio-social paradigm that embraces a multi-causal understanding of disease transmission and disease impacts on human societies and ecosystems. While striving to develop and validate a general theoretical model, it takes the well-documented and highly diverse world of late medieval and early modern Europe as its laboratory – investigating its interconnected climatic, cultural, demographic, economic, ecological, and pathogenic history. With regard to the latter, EUROpest assumes malaria, smallpox, tuberculosis and enteric diseases were major components of a disease baseline over which the most devastating disease, plague (Y. pestis), occurred. EUROpest will carry out regional case studies – from Spain to Lithuania, Greece to England – selected on the basis of available and procurable written, scientific and archaeological data. It will holistically consider the contexts of plague outbreaks identified in those regions, to understand how context both facilitated outbreaks and also shaped them, and their short- and medium-term impacts. EUROpest combines archival source analysis with archaeology, archaeogenetics, paleoecology and paleoclimatology, and subjects case studies to novel human-supervised machine-learning to identify the causal role of factors influencing regional outbreaks. As the contemporary imagination is guided in its understanding of epidemic disease by the outbreaks of the past, EUROpest’s contribution will be critical to developing more nuanced and realistic scenarios of future pandemics, academic as well as popular. With EUROpest PIs alre
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'New Digital Twins for Biological Innovation' in the context of a Horizon Europe call.

assistant: **Objectives**

Computational analysis of experimental measurements is crucial for advancing fields ranging from basic biotechnology to applied biomedicine. However, the rapid generation of increasingly complex data by laboratory equipment has outpaced the development of computational tools, leading to significant loss of valuable information. NEWTON addresses this challenge by developing Digital Twins (DTs) for (i) laboratory equipment and (ii) experimental procedures. These DTs will serve as computational mirrors, replicating the equipment used for sample characterization and the protocols employed in experiments. By capturing the intrinsic features of the equipment, how it derives experimental values from living cells, and the impact of protocols on samples, DTs will unlock unprecedented insights from experimental data. Existing computational tools could be integrated with DTs to enhance their analytical capabilities. Importantly, DTs are not intended to replace existing tools but to augment them, enabling comparisons and predictions that are currently unattainable, thus overcoming current bottlenecks. A preliminary test using a DT of a flow cytometer has already demonstrated its potential within our laboratory, allowing us to investigate bacterial phenotypes in novel ways and revolutionizing our approach to cytometry data analysis. Building on this success, NEWTON will advance initial conceptual studies to practical validation in small- and large-scale setups. Use cases during this validation phase will span biomedical applications, industrial cytometry fabrication, and bioengineering research. Looking ahead, NEWTON will assess the scalability of this technology, with a long-term vision of creating a modular DT of an entire molecular biology laboratory—where NEWTON DTs serve as fou
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Platform independent and inter-platform multimedia reference applications' in the context of a Fourth Framework call.

assistant: **Objectives**

The project aim is to prove the viability of developing multimedia reference applications on the principles of separate data and viewing components and inter-platform access. This is thought of a first step in the creation of a tool-set for the development of platform independent, inter-platform applications. The project will demonstrate that through the use of the REFEREED approach, very good quality, multimedia reference applications can be created. To the end-user it will mean better user interaction, more hardware and software choices, up-to-the-minute time-sensitive data, in a media-rich environment using existing infrastructure and technologies. To the developer it will mean less time and effort to produce state-of-the-art applications. To the publisher it will mean less costly products, that have a larger potential market, and that are more appealing than their competitors. Therefore, the major results of the project will be an approach for improved large scale multimedia reference applications and a major application using this approach. The pilot data will come from the Greek Basketball championship in order to prove real world regularly changing data and have a large audience on which to test the application. It will also provide a basis for an exploitable commercial product that can prove the virtues of the REFEREED approach in the marketplace. It will be accompanied by an extensive evaluation of both the approach and the resulting application by end-users, by publishers and by domain experts. By multimedia reference applications we mean such products as electronic encyclopaedias, lexicons, reference books, textbooks, product catalogues etc. We make this distinction to exclude at the present stage multimedia games, presentations and CBT. By inter-platform app
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'JOINT URBAN PROJECT IN TRANSPORT ENERGY REDUCTION 2 [PHASE 1]' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

The specific objectives of JUPITER 2 are :- to implement large scale projects in eight European cities, each integrating aspects of city planning and infrastructure provision, optimisation of use of transport infrastructure, innovative vehicle technologies and clean fuels, with the aim of demonstrating viable strategies for energy-saving and environmental improvement.- to achieve the minimum standards of a 20% reduction in energy consumption and pollutant emissions, at each demonstration site.- To evaluate the impacts of the demonstration projects using common methods and tools, and to advance the state of the art in this field.- To use the experiences of implementing the demonstration projects and the expertise within the consortium to develop practical guidelines to encourage the implementation of energy-efficient transport and land-use policies, which could be used by other cities.- to promote the concept of the energy-efficient city and the role of the Jupiter initiative.Each project incorporates a range of new vehicles and clean fuels integrated with innovative transport management measures to optimise the use of the infrastructure. Each city project will take place within the context of strategies to increase the use of environmentally-friendly transport modes at the expense of private motorised transport.During the course of the project, the consortium will invest in a minimum of 100 new buses and 20 vehicles of other types, powered by a range of alternative fuels. This investment will be accompanied by measures designed to influence the modal split in favour of public transport, walking and cycling, including telematics technologies, traffic regulation schemes, integration of residential/commercial/business functions and promotion of intermodality. The main tech
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The Neuronal Code of Inheritance' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Little is known about non-DNA mediated transgenerational inheritance of parental responses. If inheritance of non-genetic materials is prevalent, it could challenge our conceptions regarding the rules and limits of heredity. We are in particularly intrigued by the possibility that the nervous system can produce heritable changes. Mechanisms for propagation of responses from the soma to the germline are known. Until very recently, the possibility that any type of environmental response could become heritable, let alone somatic responses, was considered blasphemous. In C. elegans nematodes, exogenously-supplied artificial dsRNA transfers from the soma to the germline, triggering transgenerational small RNA-mediated RNA interference. It is unknown whether endogenous small RNAs can transmit specific information about the environment to the progeny. We will investigate if endogenous siRNAs, which are naturally made in somatic tissues, and in particular in neurons, produce transgenerational responses. Specifically, we will test which RNA molecules act transgenerationally, how do they mediate non-cell autonomous gene regulation, and which responses can be communicated to the progeny. What is the code that transforms particular environmental responses to specific arsenals of heritable RNA molecules? We will answer these questions, and moreover study the implications that this completely new form of hereditary has for the offspring’s survival. Can heritable small RNAs retain adaptive memory? Not only will we elucidate natural transmission of the parents’ activity from generation-to-generation, we will moreover devise means to control these mechanisms. We will engineer tools to diagnose, erase, maintain, and modulate the heritable effects, which would be important for basic resea
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Code-engineered new-to-nature microbial cell factories for novel and safety enhanced bio-production' to be submitted under Seventh Framework.

assistant: **Abstract**

The concept of METACODE is to preform genetic code engineering in microbial strains with parallel recruitment of novel bio-orthogonal chemistries for mass production of desired protein/peptide based products. In combination with computational and classical chemical synthetic approaches as well as chemo-informatics, enzyme guided evolution, synthetic metabolism, and directed evolution of microbial strains, artificial industrial microbial strains will be designed. This will enable the access to genetically robust and safe strains with added/novel functionalities and topologies from renewable resources.  These strains will be characterized with alternative reading of the genetic code (genetic firewall) and with predetermined chemistries (metathesis), as well as necessary robustness for efficient industrial use.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Sleep and episodic memory consolidation:  ‘No-report’ paradigms, brain mechanisms, and dementia' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Episodic memory is a core element of the human mind, but how experiencing an episode consolidates into long-term memory remains a central unsolved question in cognitive science. We will test the hypothesis that hippocampal-cortical dialogue (HCD) during sleep promotes memory consolidation, a hypothesis that has been largely beyond direct testing in humans to date. Moreover, transcending report is essential, since it remains unclear if sleep improves memory per-se, or the ability to access and report memories. Conventional paradigms do not facilitate sleep and memory research in dementia, where it is vital. Based on my expertise, ongoing studies, and preliminary results, I propose a unique approach to address these gaps by combining novel approaches to recording and stimulating brain activity in human sleep with novel ‘no-report’ memory paradigms. We will go beyond the state-of-the-art in three synergistic domains: (1) Develop an ecological ‘no-report’ paradigm to study episodic memory, and its consolidation during sleep. (2) Test the role of sleep HCD in mediating human memory consolidation. (3) In dementia and aging, we will investigate to what extent disrupted HCD during sleep impairs memory consolidation, and whether noninvasive neuromodulation can improve memory in dementia. The proposed research has the potential to elucidate fundamental principles and transform conceptual insights of how sleep promotes episodic memory consolidation.