RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Development and preclinical testing of cord blood-derived cell therapy products' under Sixth Framework.

assistant: **Concept**

Cord blood is a widely recognized source of hematopoietic progenitor cells for human transplantation in pediatric and, to a lesser extent, also adult patients affected by different hematological disorders. The therapeutic perspectives of cord blood has been recently widened by the discovery that it contains pluripotent stem cells, capable to give rise, in vitro and in vivo, to other than hematopoietic cells. The present project is aimed at investigating the potential of cord blood stem cells for differentiation and tissue repair, with the final goal to develop novel technologies for pre-clinical testing of cord blood-derived cell therapy products.Therefore, the main part of this project will be dedicated to set up and validate innovative technologies for the isolation, amplification and differentiation of pluripotent cells from cord blood, including immunological assays for the evaluation of their immunoreactivity and animal models of human diseases to test their safety and efficacy. Moreover, the presence of a SME in the Consortium is specifically aimed at translate the results obtained from the basic science into GMP procedures to be used in phase I/II clinical protocols.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Parents and Technology in Cyberbullying: Intervention and Prevention for Future Experts.'.

assistant: **Objectives**

Cyberbullying is a significant social, health and behavioural concern throughout the EU and worldwide, yet crucial areas in its prevention and intervention have largely been side-lined, namely the key role of parents, as well as the role of gender, disability, ethnicity and sexuality. PARTICIPATE will address this research and action gap, by delivering a world-class multi-sectoral, multi-disciplinary doctoral training program incorporating plans for substantial networking and exchange of information, expertise and action potential regarding the nature and extent of cyberbullying across Europe. By focusing on parents, as well as on gender, disability, ethnicity and sexuality, the project aims to empower both parents and young people, creating a safer space online for our youth, while placing Europe firmly at the forefront of cyberbullying research and practice. This DN brings together many of the foremost world leaders and cutting-edge researchers in the areas of cyberbullying prevention, and is grounded in scientific excellence provided by academic partners across Europe (N=6) with extensive previous experience of collaborating together. This partnership, in conjunction with a strong and diverse range of non-academic partners, including NGOs, youth foundations and internet safety organisations (N=8), will provide a robust multi-disciplinary and inter-sectoral approach to finding solutions to cyberbullying. The objectives will be achieved through a unique combination of individual and collaborative research work, non-academic secondments and workshops on scientific and applied skills facilitated by the academic/non-academic composition of the consortium. The findings generated will produce both practical, research-based programs, and European guidelines on cyberbullying
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Development and validation of a powder HIP route for high temperature Astroloy to manufacture Ultrafan® IP Turbine Casings' under Horizon 2020.

assistant: **Concept**

This is a response to the Call for Proposal under Clean Sky 2 and JU to manufacture IP Turbine casings for the new generation Ultrafan® engine from Astroloy using Net Shape Hot Isostatic Pressing of powder (NSHIP). Astroloy with high γ’ volume fraction have the required high temperature properties but it is unforgeable. Thus, Powder-HIP is the most promising process route for this alloy though this technique presents several challenges such as presence of PPBs in the HIPped microstructure, the high cost of powder and HIP-tooling. HUC, making usage of the background technology will face and overcome these challenges and will take a step further tackling technology gaps alongside the material capability, basic mechanical behaviour and impact in the presence of the exposure with the ultimate goal for this technology to be fully tested in the relevant UltraFan® Demonstrator engine environment.The main objective of HUC is to improve the buy to fly ratio from the typically achieved 9 through the conventional cast and wrought route to less than 3 through NNSHIP being the material developed able to withstand engine relevant conditions with and without exposure guaranteeing its ability to contain. The work plan includes the following main activities:1. Development and Optimisation of a powder HIP processing for Astroloy2. Characterisation of mechanical properties to generate a database which supports the component design3. Development of experiments and numerical simulations to assess the material´s behaviour under dynamic and ballistic conditions4. Characterisation and understanding of mechanical properties with exposure at high temperatures5. Development of low cost tooling for HIPping high temperature superalloy casings6. Development and validation of process modelling capabi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Establishment of cortical polarity in the one-cell C. elegans embryo', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Throughout biology, from a single-celled bacterium developing into a mother cell and endospore, to the differentiation of gut epithelium in higher eukaryotes and even the morphological changes required in the generation of neurons within the human brain, the ability of a cell to generate intrinsic asymmetry plays a crucial role in development.  In higher eukaryotes, this ability to polarize requires the establishment within the cell cortex of domains, which acquire distinct molecular and functional identities. One of the best-studied examples of cortical polarity is the one-celled C.elegans embryo, which undergoes an asymmetric division critical for sequestering the germ cell lineage.  Prior to cytokinesis, a complex of conserved polarity proteins (PAR-3, PAR-6 and atypical protein kinase C - aPKC) is segregated to the anterior half of the embryo, while at the same time, a posterior domain containing PAR-1 and PAR-2 forms in the complementary posterior region.  While it is believed that mutual antagonism between these anterior and posterior polarity complexes is critical to the formation and maintenance of these domains, the mechanisms underlying this process are poorly resolved and no coherent model has been achieved.  This proposal takes a multi-disciplinary approach in order to explore how specific kinetic properties of PAR proteins give rise to discrete and robust cortical domains.  To this end I will a) Use confocal microscopy to measure in vivo protein dynamics including cortical diffusion and cortical exchange rates and to quantify boundary gradients; b) Analyze how these parameters are affected by depletion or mutation of specific PAR components, and c) Develop and test quantitative models for maintenance of discrete cortical domains.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Growth and Shaping of Soft Tissue' (SOFTGROWTH) under Seventh Framework.

assistant: **Objectives**

Many natural structures are made of soft tissue that undergoes complicated continuous shape transformations that accurately and reliably serve specific elaborate tasks. Such processes can be slow, as in growth of a tissue, leading from an initial, featureless, shape to the desired elaborate structure of the adult organ. In other cases continuous shape transformations of soft tissue are rapid and are used for the production of mechanical work, as in the case of the action of the hart. Our understanding of natural growth is limited and our ability to produce controlled motions of soft tissue is poor. A central problem in both cases is how to incorporate all local changes in the tissue in order to determine the mechanical state of the entire body. In addition, there are problems regarding how to measure a deforming body and how to characterize the deformation. Finally, there is a problem of how to control motion and growth in artificial and natural soft tissues. I propose a multi disciplinary study, based on an approach I have started developing. According to it there is an underlying common mathematical way to describe continuous large shape transformations of stretchable tissues. This approach clearly defines the way to determine the mechanical state of a deformed tissue and to measure its local growth/deformation. The project will involve a theoretical study within mechanics and differential geometry, an experimental-physics work, which will be focused on the construction of responsive deformable tissue elements and measurements of their shape evolution, and a biophysical work, in which the natural growth and motion of leaves will be measured and will be correlated with biological activities. Such an integrative study has the potential of advancing our understanding of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'A groundbreaking smartlock system to increase security and control of entry points'.

assistant: **Objectives**

LEAPIN has developed a new type of access control and unlocking system. Digital Keys is a Software Development Kit that utilises apps and web-based software to set, send, receive and revoke time sensitive one-time use passwords (keys) to provide access anytime anywhere. A secure encrypted technology is used to overcome concern related to fear of hacking and security. The traditional magnetic stripe technology is outdated and the system is subject to regular failures. The installation of innovative smartlocks delivers a more reliable and secure system. LEAPIN’s patented technology allows Digital Keys users to open doors with their smartphones, to self check-in to accommodation/assets with their smartphones, to web check-in to their accommodation/assets, to continue to use keycards linked with Near Field Communications and enable complete self-management of accommodation without human interaction. Digital Keys require no supporting network infrastructure through the use of a one-time password cloud based software. The flexibility of remotely controlling and managing access to properties provides convenient accessibility and does not restrict operating hours. Within the overall project, LEAPIN aims to: implement Near Field Communication technology and Bluetooth Low Energy technology features into the LEAPIN Software Development Kit; undertake at least three pilot trials of the smart lock in hotels in 3 EU countries; undertake a market replicability test of the software platform and its functionality; and establish a sound marketing and commercialization strategy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Recovery and Return-To-Base European Reusable Micro-Launcher Project' (RRTB).

assistant: **Innovation**

The rise of small satellites and large constellations is changing the satellite industry. Due to the growth of the small satellite market, launch has become the bottleneck of the industry. According to MT Aerospace the micro-launcher market will grow as much as four to seven times in the next decade, with a full market potential of up to €7B. The RRTB consortium believes that a tailored service for access to space for small satellites is required. However, micro-launchers regularly have higher launch costs per kilogram than bigger launchers. Today, the cornerstone of this emerging market is the economic viability of launching small payloads at high frequencies to dedicated orbits. According to the RRTB consortium, technological development and vehicle reuse are fundamental steps to bring down the cost of launch and access-to-space. This project investigates the recovery and return to base system (RRTB) for the first stage of the MESO launch vehicle. The recovery and return to base system is divided into two parts:1.Passive atmospheric reentry: The atmospheric reentry of the first stage of the vehicle will be a passive reentry. During the project this phase, together with its required hardware, will be investigated and defined during the project by Pangea Aerospace together with Deimos Space and VKI. 2.Horizontal landing: Landing of the first stage of the vehicle is intended to be performed using a novel patent pending horizontal landing technology that uses electric ducted fans situated in both sides of the first stage of the launch vehicle to brake the fall of first stage, control it and perform a safe landing. This phase will be studied by TUM and Pangea Aerospace.Furthermore during the project the structural design and analysis of the MESO launch vehicle, as well as
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on '‘Right’ Futures: the Liminal Political Timespace of the ‘Real Right’ in Chile and Italy'.

assistant: **Concept**

RightFutures inquires into the ways future-oriented activities shape the political experiences of youths (18-35 yo) who identify with the self-defined ‘Real Right’ in Italy and Chile. RightFutures research question (RQ) asks: “how and why do Youths who identify with the self-defined ‘Real Right’ in Italy and Chile engage with multiple futural orientations through political performances, events, activities, and materialities?”. RightFutures investigates the RQ through three specific objectives, focusing on security and defence, the (dictatorial) past, and the nation. It uses the method of comparative ethnography (data will be collected through participant observation, extended interviews, participatory mapping, and secondary sources). RightFutures will focus on Youths who identify with groups that have inherited the countries’ dictatorial legacies, acknowledging that the existence and practices of these groups become pivotal points used to renew the dictatorial past’s rightfulness. These groups thus preserve, perpetuate, and renew the dictatorial past’s contemporary relevance and permanency within democratic structures. Its innovative contributions are: i) investigating the ‘Real Right’ using a novel analytical focus through a futural temporal perspective; ii) proposing a novel ethnographic comparison between Italy and Chile to explore the global relevance of this topic; and iii) producing novel understandings of the ‘Real Right’ in Italy and Chile.


**Keywords:** Fascism, Far-Right, Youths' Political Experiences, Chile, Italy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Exploring the combined role of genetic and non-genetic factors for developing Age-Related Macular Degeneration: A systems level analysis of disease subgroups, risk factors, and pathways', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Age-related macular degeneration (AMD) is the world’s most important age-related blinding disorder. The current proposal utilises epidemiological data describing clinical phenotype, molecular genetics, lifestyle, nutrition, and in-depth retinal imaging derived from existing longitudinal European epidemiological cohorts and biobanks to provide three major insights needed for long-lasting prevention and therapy for AMD: (a) the development of robust algorithms utilising genetic and non-genetic risk factors to identify personalised risks of developing advanced wet and dry AMD; (b) the identification of novel biomarkers for further stratification of disease risks.New insights from (a)+(b) will be used to elaborate preventive medical recommendations for highrisk subgroups of AMD patients; and (c) the identification of molecular drivers/biological pathways relevant for onset and progression of advanced AMD that will be used to identify and validate new therapeutic targets.Key deliverables are:1. Determination of AMD frequency in Europe, and assessment of AMD risk for phenotypical, genetic, environmental, and biochemical risk factors and their interaction. (WP1-3)2. Development of a web-based prediction model for personalised risk assessment of AMD based on integration of risk profiles derived from retinal imaging, molecular genetics, assessment of lifestyle, and biochemical testing. (WP4)3. Modelling and functional characterisation of pathophysiological pathways identified from integrated analysis of current knowledge and the above risk profiles. (WP5)4. Experimental testing and interpretation of pathophysiological consequences of risks at the molecular level. (WP6)5. An extension and refinement of the prediction model (WP4) based on work in WP5 and WP6 to generate clinical g
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Designing, Managing and Debugging Quantum Networks', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

QUESTING is a groundbreaking Doctoral Network (DN) initiative aimed at revolutionizing the field of Quantum Technology by addressing critical gaps in interdisciplinary education and training. This program will cultivate a new generation of ""Q-System Innovators,"" equipping 15 doctoral candidates with expertise in quantum networks, hybrid classical-quantum systems, and interoperable cultural co-design. By integrating mathematics, physics, computing, and communications engineering with socio-cultural and ethical perspectives, QUESTING pioneers an innovative approach to building scalable, robust, and adaptive quantum systems.QUESTING tackles foundational challenges in quantum networking, including entanglement optimization, fault-tolerant design, and resource-efficient hybrid systems. By leveraging advanced methodologies such as small-world network modeling, Bayesian optimization, and quantum game theory, it addresses issues like the fragility of entanglement, network scalability, and adaptive fault detection. The program’s innovative approach encompasses the development of key performance indicators, physical models for noise and decoherence, and algorithms for resource management, ensuring seamless integration of quantum technologies with existing classical systems.The program's holistic methodology spans from theoretical advancements to real-world applications, including secure quantum communication, distributed resource management, and sustainable network topologies. Through its unique blend of participatory research, co-design processes, and industry-academic collaboration, QUESTING ensures alignment with global challenges such as cybersecurity, digital transformation, and equitable access to emerging technologies. This initiative is instrumental in advancing the Eur