RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Prevention, diagnosis and molecular characterisation of mismatch repair defect-related hereditary cancers of the digestive system' (2002-2006).

assistant: **Innovation**

We focus on hereditary cancers of the digestive system associated with microsatellite instability, hereditary non-polyposis colorectal cancer (HNPCC) and familial gastric cancer (FGC). Microsatellite instability is the result of a defective mismatch repai r (MMR) system. Germline mutations in MMR genes are found in families with HNPCC, characterised by development of colorectal cancer and extracolonic malignancies, particularly cancer of the endometrium. Evidence is accumulating that also a subset of FGC i s MMR-related as families have been identified with tumours showing microsatellite instability. MMR gene mutations have not yet been identified in these families. In HNPCC, identification of MMR gene mutations has helped in identifying individuals at risk when a clear pathogenic mutation was found. Many families, however, in particular those with less penetrant HNPCC, remain genetically unresolved. Furthermore, in a large proportion of families mutations are identified whose pathogenic nature is uncertain (unclassified variants). Although we have made great progress in the genetic delineation of this cancer syndrome, it has hardly improved early diagnosis or treatment of cancer. To improve genetic testing we will (1) determine the role that known MMR genes play in both cancer syndromes and identify new MMR-related genes underlying HNPCC or FGC; (2) set up comprehensive functional assays to determine the role of unclassified variants in MMR related genes; (3) identify tumour cells at very early stages in faec es by enhancing the sensitivity of MSI determination; (4) profile mutations accumulating in tumours as a consequence of MMR deficiency in order to get a better insight in tumour development, which can be instrumental in clinical management/tumour treatment . Our p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'FORALIEN: towards the development of a foraminiferal Non-Indigenous Species index' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

FORALIEN (FORaminifera ALIEN) is a project aiming to fill the lack of knowledge of non-indigenous (i.e. alien) benthic foraminifera (marine protists) observed recently in Europe to make them a reliable indicator of human impacts for a better integration into biomonitoring surveys in the context of the European regulation of the Marine Framework Strategy Directive. To do so, I plan to sample surface sediment and sediment cores of several sites on the West Swedish coast which are composed of understudied harbours, in terms of foraminifera but known places of pollution and introduction, and fjords where some have been recently observed, such asTrochammina hadai and Nonionella sp. T1. Among those NIS, Ammonia confertitesta could also occur there. This species has been recently identified as a pseudo-cryptic species included in the Ammonia tepida morphotype with two other very morphologically similar species, A. aberdoveyensis and A. veneta, that are native species in Europe.  In a first place, I will morphologically identify these NIS by defining easy criteria of identification and apply a recently developped method allowing an easy identification of the three species of the A. tepida morphotype. To complement the morphological method I will apply novel methods, genetic (digital Polymerase Chain Reaction) and deep learning models, to identify NIS foraminifera quickly and reliably assess their efficiency in biomonitoring surveys. Secondly, I will use methods precedingly described and sediment samples to analyse the spatio-temporal distribution and time of arrival of NIS in the region. This would result in the development of a NIS index to asses their impact on native species. Finally, environmental parameters will be measured to define the unknown ecological requirements of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'PieceOfCake: an AI-driven chatbot to manage complex business data' (POC), addressing dissemination and exploitation.

assistant: **Impact**

The complexity of business data (accounting, marketing, etc.) requires technical skills to handle and process it. However, the roles in a company that need this information to operate are usually different from the ones with those technical skills, also known as business analysts. Third-party solutions or in-house IT departments provide dashboards and reports to fill the gap. Nevertheless, this methodology is (1) expensive in terms of IT time devoted to implementation and maintenance, (2) rigid and difficult to adapt to the particular work-flow of each company, (3) slow and tedious to use. These issues can weigh down a company and translate into lost business opportunities.We propose PieceOfCake, a trained Artificial Intelligence (AI) system that allows the use of Natural Language (NL) to access complex data. Questions like “How many users visited our web during last week for the first time?” will be automatically answered in the form of NL and graphs. Our product will change the way data-driven companies operate. Mid-level managers and interdisciplinary roles (e.g. marketing) are examples of positions that will highly benefit from it. PieceOfCake will outperform traditional dashboards in terms of ease of use, agility, and speed. It will disrupt strategic decision-making and drastically reduce IT costs. It will also allow small enterprises and self-employees to keep pace with the AI wave.The feasibility study will identify which vertical (marketing, analytics, etc.) offers a higher market opportunity, what monetisation strategies work better (SaaS, white-labeling, tailored customers, etc.), and what market segment better accept our strategy.Given the expected impact AI will have in global economy, we believe our project is crucial to the competitiveness of Europe agains
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Calculational tools and methods for physics at large hadron collider' (CAMTOPH).

assistant: **Concept**

For the purpose of studying the most fundamental structure of matter and space-time, the European community has invested several billions of euro into the LHC collider located at European Organisation for Nuclear Research (CERN) in Geneva. Thanks to this a nd previous experiments, CERN plays key role in European Particle Physics, winning the competition with US. In order to fully exploit the LHC experiment appropriate precise theoretical calculations derived from Quantum Field Theory are necessary. Our group from H. Niewodniczanski Institute of Nuclear Physics, forming the key scientific staff of the project, has expertise in this class of calculations, involving Monte Carlo simulation techniques, which we have done for the previous CERN experiments, LEP1 and LEP2, in the electroweak sector of particle physics. In this proposal we plan to develop similar Monte Carlo tools and perform calculations for the LHC experiments. This requires extension of our expertise to the QCD sector of the Standard Model. Transfer of knowledge from CERN, which we choose as the partner institutions, is mandatory for successful accomplishment of this project. The existing calculational tools for hadron colliders are, generally, restricted to precision of order of 10%, whereas forthco ming LHC experiments require precision 1%. The goal of the proposal is to provide such precise predictions, mostly in a form of Monte Carlo simulations, for the realistic observables in the true experimental environment employing advanced methods of the so ftware engineering. The topics include: the Drell-Yan-type processes (inclusion of one-loop corrections and better quality parton showers), new methods of simulating spin effects in decays, extension of Drell-Yan-like results to other two body final states (WW,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'A novel 3D Stereoscopic e-learning SolutIon for theoretical Surgical Training' to be submitted under Horizon 2020.

assistant: **Abstract**

The SurgASSIST project aims to improve surgical care by changing the way surgeons are educated. The SurgASSIST project provides an online educational program, the INCISION Academy, that uses 3D visualizations (stereoscopic videos and animations) to teach surgical procedures step-by-step, based on state-of-the-art scientific research and best-practice surgical care. Surgery is a three dimensional trade and the use of 3D stereoscopic techniques creates a unique and realistic online environment in which residents and surgeons can learn, train and be tested on best-practice based surgical procedures and anatomy. With the INCISION Academy prototype, the value of this innovative educational approach has been demonstrated. To reach market introduction of the INCISION Academy, the SurgASSIST consortium will undertake activities to establish a strong value chain from production to distribution: (1) complete the INCISION Academy curriculum, (2) add 3D virtual reality online surgery to increase product value, (3) establish the LMS system for worldwide distribution, and (4) create the commercialisation strategy. Potential users, surgical residents, surgical trainers, and surgeons, cope with an ever increasing workload and need tools to relieve work pressure and improve quality. After this project, the INCISION Academy will be available as worldwide surgical online training tool to train surgical residents with higher quality than before while saving time of surgical trainers. In addition, the INCISION Academy provides a timesaving online alternative for continued medical education of surgeons (CME). The European markets for training of surgical residents and CME amount to € 187,5 and € 158 million respectively. The easy-access, unparalleled high quality, and use of 3D technologies
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Plasticity of thresholds for recruiting and applying synaptic inhibition in vitro and in vivo' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

The project will involve a systematic examination and derivation of thresholds for recruiting and applying inhibition using simultaneous intracellular patch recording in slice and in vivo in the necrotic of rat, as well as computer simulations for prediction and hypothesis testing.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Comprehensive Investigations of Aerosol Droplet Surfaces and Their Climate Impacts' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

By serving as cloud droplet seeds, aerosols represent the largest negative (cooling) and most uncertain climate forcing. Particulate matter is also a major contributor to air pollution, attributed to ~7 million annual deaths. Aerosol surfaces hold the greatest source of uncertainty for atmospheric chemistry and climate impacts. Surfactants are now routinely identified within atmospheric aerosol samples, and surface tension governs the fraction of particles that activate into cloud droplets, significantly impacting aerosol-cloud climate effects. Sunlight-driven interfacial reactions have recently emerged as important modifiers of atmospheric composition and proceed via unique pathways relative to bulk solutions. A complete understanding of aerosol climate and health impacts requires detailed knowledge of aerosol surface composition and reactivity. However, few approaches directly interrogate droplet surfaces, hindering incorporation of surface-mediated processes into climate and air quality models. This project will study directly the droplet-air interface of picolitre droplets in size ranges relevant to growing cloud droplets to develop a comprehensive, molecular level understanding of interfacial composition, reactivity, and climate and health impacts. Aerosol droplet surfaces will be studied with novel, sensitive approaches. The dynamic and equilibrium partitioning of surfactants to aerosol droplet surfaces will be investigated directly for the first time, providing information required for accurate cloud droplet activation predictions. Entirely new approaches to selectively analyse the surface and bulk molecular composition of a levitated micron-sized droplet by mass spectrometry will allow direct investigation of chemistry on aerosol surfaces. Together, these approa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Implementation of a dynamical Pollen Module and the transformations of the pollen including feedbacks in a numerical Weather Forecast Model' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The main goal of the proposed project is to provide an advanced mathematical model (WRF-BioChem) for modelling the emission, dispersion and concentration of bioaerosols at the regional scale. The model will with this development be able to handle feedback mechanisms between biology, chemistry and weather. The model is developed to go beyond state-of-the-art by developing the mathematical model for oak pollen and by doing it at the species level. The project supported by a three companion projects on grass pollen, fungal spores (Alternaria) and pathogens – all at species level. These projects deliver the needed resources for detection. As such the mathematical model will be a validated model that will be generally applicable for bioaerosols including pollen, pathogens and fungal spores. Detection of pollen will be carried out by supporting staff and projects using both traditional methods based on optical detection at the genus level and next generation sequencing at the species level. This proposal requires multidisciplinary approach to the problem as pollen appearance and behaviour in the air is dependent on many factors, including meteorological conditions, chemical composition of the atmosphere or surface properties as well as feedbacks between these elements. WRF-Chem currently used in air quality modelling will therefore be adapted for studying transport of bioaerosols in a way consistent with the transport and transformation of other air pollutants. Until now, no atmospheric model is used for the simulation of pollen at the species level in either Europe or in USA. Also, it will be the first time simulations of oak pollen will be possible in Europe or in USA. Also, it will be the first time simulations of oak pollen will be possible in Europe. Finally, it will be
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Biodiversity, abrupt ecosystem shifts and restoration: understanding their links to sustain drylands under global change' (BIOSHIFT), addressing dissemination and exploitation.

assistant: **Impact**

Global change and desertification drivers, such as climate change and increased fire frequency, make drylands more prone to abrupt shifts that can lead to the emergence of degraded states unable to provide key ecosystem services and to sustain life. However, we still lack an in-depth understanding of the prevalence and triggers of these shifts, and of the identity of those ecosystem attributes and services that are most affected, across global drylands. These uncertainties arise largely from the absence of global monitoring efforts and experiments investigating temporal changes in biodiversity and associated ecosystem services. Furthermore, the lack of a systematic evaluation of the ecological impacts of restoration actions, such as tree planting, hampers our capacity to assess their usefulness to prevent abrupt ecosystem shifts and to combat climate change and desertification. BIOSHIFT will combine global-scale experimentation and temporal field surveys with state-of-the-art Earth observation, mathematical modelling, -omics approaches, and statistical analyses to tackle these key knowledge gaps. Specifically, I will: i) determine the prevalence, drivers and consequences of abrupt ecosystem shifts in drylands, ii) assess whether in situ temporal changes in dryland biodiversity and ecosystem services exhibit threshold-like responses along global aridity gradients, and iii) conduct the first systematic field assessment of the ecological impacts of tree plantations and their capacity to prevent abrupt ecosystem shifts in drylands worldwide. By doing so, BIOSHIFT will make a major leap forward in our understanding of abrupt ecosystem shifts and provide unprecedent insights on how to monitor and manage them. This project will also provide the ecological underpinning to high
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Assimilation of satellite data for regional air pollution forecasting' to be submitted under Sixth Framework.

assistant: **Abstract**

The scientific objective of the proposal is to investigate the added value ofsatellite observation for regional and continental tropospheric air pollutionstudies. Satellite observations of trace gases in the troposphere have become available only recently. Most of our sparse present day knowledge of air pollution is based on routine surface observations at a limited number of sites, and a few aircraft measurement campaigns.The high-resolution CHIMERE Chemistry Transport Model (CTM) will be used in conjunction with GOME, SCIAMACHY, and OMI satellite data, to (1) study if these data sets can contribute to improved surface emission inventories and air pollution forecasts for Europe, (2) identify shortcomings in the transport and chemistry ASSSATAIRPOLs of CHIMERE, and (3) quantify how much realistic tracer profile information from a high-resolution CTM can improve the satellite retrievals.The approach is to develop innovative chemical data assimilation algorithms. These algorithms will be used to assimilate nitrogen dioxide (Nu2) tropospheric columns into CHIMERE in order to constraint nitrogen oxide (NOX) emission used as input in the model. An improved description of NOX sources will have an important positive impact on air pollution forecasts. The project will build on the successful assimilation of ozone surface observations in CHIMERE, as part of my PhD work, and the expertise of the host institute on satellite NO2 retrievals, global-scale atmospheric modelling, and advanced data assimilation techniques.The work will be done in the Atmospheric Composition Division led by Prof.H. M. Kelder, at KNMI, The Netherlands. The project involves my collaboration with this research group with many years of expertise in atmospheric chemistry research on a global scale, which is c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Brazilian European Consortium for DTT Services'.

assistant: **Innovation**

The  main objectives of the Beacon Project are:To perform research on innovative Digital Terrestrial Television (DTT) services addressed to the  tLearning  domain notably customized for the Brazilian specific needs related with social inclusion issuesTo establish a Brazilian -  European Consortium  which will manage the exploitation of the assets and the services implemented by the project activitiesTo disseminate the project results and to provide research results and feedback data analysis of pilot run to the Brazilian Public Administration in order to contribute to the relevant policy making process in the field of deploying the DTT technology and servicesThe main expected outputs and results are the following:Research on innovative DTT eLearning methodology and on the interoperability between the European (DVB) and the Brazilian (SBTVD) respective technologies performedInnovative interoperable (DVB-SBTVD) tLearning pilot services developed (the pilot services are addressed to the Brazilian Public Administration employees and citizens in order to foster the social inclusion)Operating DTT platform implemented and sited in the State of São Paulo (Brazil)DTT Services Centre aimed at  designing, developing  and providing broadcasting of tLearning  services in the state of São Paolo implementedtLearning pilot run services deliveredPilot services data collection and experimentation results gathered and available Evaluation of pilot services and experimentation results performedExploitation model identified and relevant plan developed Brazilian - European Consortium established The project work has been broken down into the following Work Packages: WP1  Needs Analysis and User RequirementsWP2  tLearning services design  and developmentWP3  DTT platform design and deployment