RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Development of structural DEsign REcommendations for STeel ARches' (DERESTAR) under Seventh Framework.

assistant: **Objectives**

The proposed study is aimed at the investigation of the nonlinear behaviour and the development of design rules and recommendations for steel arches in the form of European Standards for construction. Today, Eurocode 3 considers only straight members. Arches have to be designed according to the same methodology and the same values of parameters as straight members. Some authors have already proposed adjustments of these parameters in order to provide higher safety and economical design of arches. Nevertheless, by using methods developed for straight elements, these authors neglect two specifics features induced by the curvature of the arch. The first one is linked with the production process: usually curved beams are produced by cold bending of straight beams, so that the distribution of locked-in stresses or residual stresses is completely different in arches in comparison to straight beams. The inelastic behaviour of arches will thus be very different. The second one is the out-of-plane bending of the arch cross-section due to the curvature. The transverse stresses that develop in a bent arch reduce the cross-sectional resistance. The proposed study will thus focus on the influence of these two phenomena on the overall inelastic behaviour of arches. This will result in an enhanced fundamental understanding of the behaviour and in the formulation of a design method for steel arches subjected to bending and compression, which may be later included in the building code.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Hippocampal-prefrontal synaptic transmission in cognitive function' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Neural circuitry underlies human behavior in all of its forms. High-level ‘Executive’ regions such as the prefrontal cortex (PFC) are the subject of particular interest as functional imaging, electrophysiological, and post-mortem studies have shown cellular and neurophysiological abnormalities in these regions associated with psychiatric disorders (e.g. schizophrenia, mood disorders, and  addiction). The prefrontal cortex is one of the most highly interconnected regions of the brain, integrating inputs from widespread cortical and subcortical regions and transmitting information to an equally diverse set of targets. Major sources of synaptic input into the PFC include the thalamus and the hippocampus, which convey sensory, contextual and spatial information to be processed in the PFC and guide decision making and goal-directed behavior. A direct synaptic connection between the ventral hippocampus and the prefrontal cortex has been proposed to subserve the synchronization of activity between these two regions in defined behavioral states. Recent studies have indicated that the organization of PFC neurons that receive direct hippocampal input might support the entrainment of PFC activity to hippocampal theta oscillations. The goal of this proposal is to identify the prefrontal neuron population which receives direct hippocampal input and test the contribution of these neurons to cognitive processing and emotional states. Using an innovative combination of imaging approaches, electrophysiology and optogenetic techniques, we will first quantify the functional properties of hippocampal-prefrontal synapses and then examine the effects of neuromodulation on the properties of these synapses. Finally, through trans-synaptic labeling we will directly manipulate the activity of ce
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'European concerted action for the support of the hot dry rock geothermal energy R&D activities 1998-2000' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

The 1998-2000 European HDR research programme at Soultz (France) represents the transition from a scientific underground exploration programme which started in 1987, into the industrially led development phase of a Scientific Pilot Plant (30-50 MW, at 200(C) using a revised HDR concept in a Graben setting. A four months circulation test was performed in the summer of 1997 (using a down-hole pump) which demonstrated that 25 Vs can be circulated continuously through t he stimulated system. Various diagnostic methods including tracers were used to evaluate the performance of the reservoir/heat exchanger which gave outstanding results [> 142(C output temperature, no fluid losses, reservoir impedance 0.2 MPa/l/s with 450 m well separation, 3000-3500 m depth]. Scope of the concerted action In the previous 10 years the EC support was organised within the frame of shaedd cost actions. Presently, it would appear to be more convenient to organise the EC support within a framework of a concerted action because of the following elements: The activities involve 14 academic and industrial teams from France, Germany, Italy, UK and Switzerland covering domains from mud logging to complex mathematical modelling. The overall management of such a wide spectrum of activities requires the continuous support of a co-ordinating body incorporating a permanent multinational European team on site in order to perform the concertation tasks and engineering required as support services for the collective scientific activities drilling and pumping operations, equipment, maintenance of sites and wells,permanent on site support to scientists with heavy operational equipment,...). A central management team is the only way to perform these tasks under reasonably safe, and cost effective conditions while
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Researchers, key drivers of growth in Europe' under Horizon 2020.

assistant: **Concept**

Under the motto Researchers, the key drivers of growth in Europe, the European Researchers’ Night in Madrid aims to highlight the important role researchers play in European citizens welfare not only as the engine of technological innovation but also by their contribution to the advancement of knowledge in Europe and beyond, finding answers to the main challenges facing modern societies.The MadridERN project as a communication and public engagement action is addressed to citizens of the Region of Madrid that aims to bring researchers and their work closer to the public at large and to promote research careers among young people without gender barriers from very early ages. To achieve this goal a wide and strong awareness campaign with a sound communication plan will be launched combining the traditional communication vectors (written press, radio, tv public advertising or street adverts) with the new ones (websites, social networks: YouTube Instagram, Facebook, LinkedIn and Twitter) with the purpose of making known the event and if possible to become “trending topic” for a while.The event aims to attract as much people as possible by transmitting the main messages of the Night, i.e: Science is for all of us; The diversity of Researchers, Researchers are amongst us; Researchers are ordinary people with an extraordinary job; Research is fun; Being researcher is exciting; Researchers improve your everyday life; Play researcher for a night; Discover what researchers do and can do for the welfare of Europe.


**Keywords:** European Researchers´ Night, researcher, society, public recognition, public engagement,  research job, RRI, schools, citizens, entrepreuners, students
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'NANOphotonic DEvice for Multiple therapeutic drug monitoring' (NANODEM).

assistant: **Innovation**

Project aim is the development of a novel therapeutic drug monitoring point-of-care-testing (POCT) device for the measurement of immunosuppressants and related metabolites in transplanted patients. The new device will allow the automatic measurements of therapeutic drugs and metabolites characterized by a narrow therapeutic range and serious potential side effects. Clinical benefit will be an optimized dosage of the respective therapeutical drug. The patient will be connected to the device by an intravenous microdialysis catheter to allow 48-h online measurements. Based on this minimally-invasive approach, the therapeutic drugs and related metabolites will be monitored at short time intervals. The need of mixing the dialysate with the chemical reagents and the necessity of incubation times for the bioassay implementation, unavoidable procedure for bioanalyte detection, implies that a continuous measurement of such analytes is impossible, but the miniaturisation down to micro- and nano-scales will lead to very short time intervals, of the order of a few minutes. Heart of the device will be a multi-parametric optical chip, which will make use of the recent developments in nanotechnology to convert the concentration changes of the analytes in detectable luminescent signals. Essential sections of the device will be also:i) the microfluidic circuit before the chip, where the dialysate is mixed with the reagents necessary for the implementation of the biological assay;ii) the optical detection system which must be characterised by high efficiency and strong compactness;iii) the compact hardware control unit and user interface that allow instrument control and data handling.The integration of all these sections within the POCT stand-alone device requires the convergence of com
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Thyroid hormone and development of cardiomyocytes derived from human embryonic and induced pluripotent stem cells' to be submitted under Seventh Framework.

assistant: **Abstract**

Human embryonic stem cells, and embryonic-like induced pluripotent stem cells made from adult human skin, can differentiate to form beating cardiac muscle cells (cardiomyocytes).  These stem cell-derived cardiomyocytes (SC-CM) are being investigated for use in cardiac repair, but also as a model system for research or drug toxicology. Their human origin, stability in culture and ability to be easily genetically modified in culture makes them far superior to present sources.  Immediately after differentiation, SC-CM have the characteristics of immature foetal or neonatal cells in terms of contraction, growth and intracellular signalling. To realize their full potential, they need to grow towards the adult cardiomyocyte in these respects. We have evidence that this occurs in culture, over time-frames of 3-6 months, and that reproducing the stimuli for maturation can produce or accelerate these changes.  One key maturational stimulus is thyroid hormone, and the first part of the project will apply this to SC-CM. However, the foetus has evolved sophisticated mechanisms to protect itself from maternal thyroid hormone, to prevent premature development.  Intrinsic enzyme systems and receptor expression levels carefully control the intracellular environment with respect to levels of T3, the active agent, to preserve the natural staged differentiation and maturation programme.  Particularly, an enzyme called D3 keeps levels of T3 tonically low.  In the second time we will investigate the synergistic effects of adding T3 and down-regulating D3 on the rate and extent of maturation of the SC-CM.  In the adult, cardiac growth programmes in response to increased load (hypertension for example) have been classified as pathological, while that controlled by thyroid hormone has been def
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Photon-photon and spin-spin Entanglement using Diamond-based impurity Elements: Silicon, Tin And Lead' in the context of a Horizon 2020 call.

assistant: **Objectives**

Quantum technologies promise revolutionary capabilities in processing information and transmitting with security over a network certified by the principles of quantum physics. The key hardware element of a quantum network is the ‘node’, where a stationary qubit cluster perform primitive processes and communicate with other nodes by exchanging flying qubits. The interfacing between the stationary qubit cluster and the flying qubits is realised by a special ‘broker qubit’. Today, the most competitive candidates for flying and stationary qubits are photons and diamond spins, respectively, and this opportunity is being pursued worldwide. A specific emitter in diamond, the Nitrogen Vacancy (NV), has enabled landmark demonstrations of basic quantum building blocks, but faces fundamental challenges on reaching the optical qualities required to scale up. PEDESTAL offers an efficiency boost to the NV while building on key advances in diamond technology. Our goal is to create a quantum node hardware prototype with characteristics required to sustain a multi-purpose quantum network capable of implementing simultaneous quantum communications and computing. PEDESTAL will develop a demonstrator quantum node based on diamond group-4 spins, which offer specifications outperforming others. Benchmarking against the known silicon-vacancy (SiV) centre, our workhorse will be the tin-vacancy (SnV) centre, which we have shown to have outstanding qualities satisfying the requirements for a quantum node. In parallel, we will develop to maturity the less-known but highly promising lead-vacancy (PbV) centre which can operate with more feasible conditions and develop a novel technique to control spins. Our objectives include creating multi-spin and multi-photon entangled states as resource and wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Enforceable Security in the Cloud to Uphold Data Ownership' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Cloud computing is increasingly a necessary strategical ICT infrastructure component for European companies to successfully compete in the world-wide economy. The advantages of renting ICT infrastructures, platforms, and services, with easy access to scalability and elasticity, are driving an ever accelerating transfer toward the cloud of data and applications. Unfortunately, such a convenience comes at the price of the data owners losing control over their own data and any consequent misuse or security threats on them, which often limit the owner's adoption of the cloud's potential capabilities. On one hand, cloud providers can be assumed to employ basic security mechanisms for protecting data in storage, processing, and communication, devoting resources to ensure security that many medium and small companies may not be able to afford. On the other hand, data owners, when relying on the cloud, lose control over data and their processing, hence leaving them potentially exposed. Today data owners have to choose between having security but limited functionality or fully enjoying functionality but compromising on security and privacy guarantees. This situation has a strong detrimental impact on the adoption and acceptability of cloud services. Data owners may refrain from relying on the cloud for certain data, which they consider more sensitive or critical, or they use the cloud but remain exposed to the consequences of improper protection and control. The goal of ESCUDO is to empower data owners as first class citizens of the cloud. ESCUDO provides effective and deployable solutions allowing data owners to maintain control over their data when relying on Cloud Service Providers (CSPs) for data storage, processing, and management, without sacrificing on functionality. ESCU
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Carbon Dioxide Capture and Hydrogen Production with Membranes' (2007-2013) under Seventh Framework.

assistant: **Objectives**

Hydrogen membrane reactors are an attractive technology for pre-combustion carbon dioxide capture in both coal and gas fired power stations because they combine the efficient conversion of syngas into hydrogen fuel with capture of the remaining carbon dioxide in one reactor. The carbon dioxide is produced at high pressure, reducing the compression energy for transport and storage. CACHET II project will develop innovative metallic membranes and modules for high capacity hydrogen production and separation from a number of fuel sources including natural gas and coal. The DICP membrane developed in FP6 project CACHET along with novel seal and substrate technology will be scaled up and undergo long term stability testing. An optimisation design tool will be built to include the relationship of all key operating parameters; this tool will be used to specify an optimised pilot and commercial membrane module design. The project will research novel binary and tertiary palladium alloys for improved durability and permeance for application to solid based fuels derived syngas and high temperature integrated reforming processes. Fundamental research on high temperature sulphur removal systems will enable sulphur tolerant membranes to become an economic possibility.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Privacy - Appraising Challenges to Technologies and Ethics', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The vision that motivates PRACTIS is of a society that is aware of the evolving challenges to privacy posed by emerging technologies and is equipped to respond to them. PRACTIS will assess the potential impacts on privacy from emerging technologies and new scientific knowledge. It will propose ethical frameworks and legal procedures for coping with potential risks to privacy. It will explore novel policy options for addressing individuals’ changing privacy needs in the light of new technologies, as well as exploring new ethical frameworks in law and implementing guidelines for new technology or product development. Specifically, long-range horizon scanning focused on technologies that might impact on privacy will be conducted. Technologies such as nano, bio, info and cognition (NBIC) will be explored and new threats to privacy will be evaluated. In addition, trends in changing perceptions of privacy will be surveyed (including among high school students). These empirical studies will provide the basis for future scenarios of the privacy-technology interface which in turn will lead to the formulation of new ethical frameworks and legal considerations. Research methods will include interviews, expert surveys, focus groups, and brainstorming. PRACTIS will generate deeper knowledge and higher awareness among scholars and relevant stakeholders regarding the early identification of changes in privacy perceptions due to new technologies. An innovative idea to be explored in PRACTIS is the embedding of privacy issues in the development process of new technologies. By bringing leading experts in technology foresight and assessment together with specialists in ethical and legal aspects of privacy, PRACTIS offers a unique combination of disciplines that will produce new knowledge