RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Are species distributions constrained by biological timing mechanisms and the photic environment?' (PhoticEdge), addressing dissemination and exploitation.

assistant: **Impact**

Biotic and abiotic factors determine species distributions, and organisms use abiotic cues, such as the diel and annual changes in available light, to synchronize their biology to the environment. Temperature is a dominant factor determining species distributions, and under global climate change, global temperature gradients are shifting polewards, away from the equator. In contrast, the photic environment is fixed by latitude and date, and is a dominant factor in determining ecological interactions and physiology. We, however, know little about whether these static photic cues determine species distributions. I aim to elucidate the relationship between species distributions and the photic environment by studying four species of migratory flycatchers (songbirds) breeding along a latitudinal gradient spanning from 56 degrees North latitude to above the northern polar circle (66.6 °N) in Sweden. Migratory flycatchers are excellent models to test hypotheses regarding the interaction between species distributions and the photic environment, because they use photic cues for determining breeding, migration, and compass bearings. The selected species also have different breeding and migratory ranges that span the polar circle and cross the equator, thus providing an excellent comparative system for understanding constraints on the northern and southern edges of their distributions. I will bring individuals into captivity to investigate experimentally how the photic environment associated with their breeding and wintering ranges affect their ability to track the diel and annual cycles. This project will provide novel insight into the interaction among species distributions and photic environment, insight required to predict properly whether species could successfully track thei
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The Once Only Principle Project' (TOOP) targeting Horizon 2020.

assistant: **Abstract**

The “Once-Only” Principle Project (TOOP) explores and demonstrates the “once-only” principle through multiple sustainable pilots, using a federated architecture on a cross-border collaborative pan-European scale in order to identify drivers and barriers and to provide a basis for future implementations and wider use. Three pilots are implemented: (1) Cross-border e-Services for Business Mobility, (2) Updating Connected Company Data and (3) Online Ship and Crew Certificates. TOOP has the ambition to connect 59 information systems from 21 countries. The methodological approach of TOOP is based on an exploratory and agile pilot life-cycle approach to cross-border pilots, the planning and implementation of which is supported by the development of a generic federated architecture and building blocks, the identification and mitigation of barriers, including legal issues, and the evaluation of the results, with pro-active dissemination and sustainable exploitation of the results throughout the project. TOOP’s main technological innovation is a generic federated OOP architecture that supports the interconnection and interoperability of national registries at the EU level. The pilots planned are ambitious as they contain innovations and provide a basis for recommendations for future implementations and the wider use of the OOP. The project is an important learning environment for OOP in particular and European e-Government in general. The pilots are scalable and can be extended to all Member States in subsequent years. TOOP’s consortium of 51 organisations consists of 19 national administrations (or authorized thereby) from 19 different EU Member States and 2 Associated Countries. The public administrations provide effective piloting, research partners make sure that the key pre
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Smooth Ergodic Theory and Partially Hyperbolic Diffeomorphisms' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The project deals with the interplay between some local and global aspects of discrete dynamical systems. In the first part we consider several problems related to the Entropy Conjecture. For any map f on a compact manifold M there are some invariants measuring the dynamical complexity at the ‘global’ level (homological or homotopical), like the spectral radius of the map induced on homology, the fundamental-group entropy, etc. In some situations these global invariants give a lower bound for some other ‘local’ invariants, which are in general harder to compute, like the topological entropy or the volume growth. We are interested in studying the relationship between the global and local invariants for different classes of maps, in particular the relationship between the volume growth and the invariants related to the fundamental group of M. On the second part of the proposal we consider partially hyperbolic diffeomorphisms (PHDs). One can associate to the stable and unstable foliations some closed currents or transversal measures, and consequently homology classes. In some situations one can relate the action induced by f on these homology classes with the volume growth of disks inside the leaves of the foliations, and consequently with the topological entropy of the map. For Anosov systems this was done by Shub-Williams and Ruelle-Sullivan, and for PHDs this was done in some cases by Saghin-Xia. We want to investigate when one can establish such relationships, and what are the possible applications of them.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Advanced NeTwork radio Identification equipment for Universal Mobile communications' under Fifth Framework.

assistant: **Concept**

The ANTIUM project proposes to develop innovative radio measurement system concerning the planning of mobile radio networks. In particular, the aims will be to provide identification based on radio analysis of co-channels users of the network. The operator or the regulator will use such system to improve the performance and qualify the regulation of their networks. The project will study adequate signal processing algorithms for UMTS (FDD and TDD) and DVB-T systems. A demonstrator will also developed in order to qualify the algorithms and principles developed in a real environment. This demonstrator will focus on verification of equivalence between user needs and resulting elements given by the equipment.OBJECTIVESFor the deployment of multimedia mobile radio networks, the capacity of identifying base stations in the field will be necessary, and the classical trace mobile will not be sufficient. The ANTIUM project will focus on UMTS (FDD and TDD) and DVB-T future networks and will have the following objectives:1 Define the requirements of an advanced radio monitoring equipment;2 Develop or adapt signal processing techniques compatible with the requirements of this equipment;3 Develop a demonstrator implementing the selected techniques;4 Realise field tests with the demonstrator;5 Disseminate project results.DESCRIPTION OF WORKThe work will be divided in six workpackages:- WP1 : project co-ordination tasks, allowing technical and financial management, assessment and evaluation of the project, and reporting to the EC;WP2: analysis of the future radio network planning rules, for the requirement concerning co-network identification. These elements will allow selecting specific operational scenarios for UMTS (FDD and TDD) and DVB-T systems, and associated targeted performanc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'TRophic state Interactions with drivers of Aquatic greenhouse Gas Emissions' (TRIAGE).

assistant: **Innovation**

Inland waters are an integral component of the carbon cycle as they process, store, transport, and emit significant amounts of carbon. Freshwaters emit carbon in the form of carbon dioxide (CO2) and methane (CH4), both important greenhouse gases (GHG). Lakes subject to a high nutrient load in a process called eutrophication are typically characterized by enhanced primary production and depleted oxygen, variables directly related to GHG production. Therefore, with increasing nutrient load (i.e., trophic state), lakes have the potential to substantially impact GHG emission, but the relationship is poorly constrained. Climate change-induced variations in variables such as temperature and precipitation could alter nutrient loading, primary production and oxygen, which in turn could change the GHG balance of a system. Evidence suggests that lake eutrophication and climate change impacts interact and alter the lake GHG budget in non-linear ways. Moreover, eutrophication may shift the balance toward higher emissions of CH4, a more potent GHG. To date, very few studies have used a systematic approach to understanding the interaction between GHG emissions and eutrophication, which is essential for efficient management of inland waters, particularly in the face of global change. The overall goal of the project is determine how the GHG balance of aquatic systems shift along a trophic gradient and what some of the drivers of these shifts may be. The project will consist of a multi-lake survey throughout central Europe across a large trophic gradient, followed by modeling of the full GHG balance of those lakes and testing of the strength of relevant drivers. Constraining the variables that dictate the GHG balance will help to inform better management practices for mitigating climati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'New Strategies for Bond Activation and Catalysis with subvalent Main Group Complexes' in the context of a Horizon 2020 call.

assistant: **Objectives**

This proposal aims to explore the feasibility and scope of thermal and light-driven bond activation and catalysis by sub-valent group 14 Main Group (MG) systems stabilized by highly σ-donating cAAC (cyclic (alkyl)amino carbene) ligands, exploiting their reduced HOMO-LUMO energy gaps, including MG-cAAC complexes, directly bonded MG/TM ( TM = transition metal) species and unprecedented hybrid MG/TM systems.We will initially target exotic cationic MG-cAAC complexes to investigate their capacity towards the activation of common E—H bonds (e.g. silanes, boranes or amines,including ammonia), including reversibility studies. This will be followed by exploring the activation of more challenging substrates, particularly the oxidative cleavage of C—H bonds.  To enhance the capacity of activating less reactive bonds (e.g. intermolecular C—H, C—X…), as well as to enable more accessible reversibility routes (e.g. reversible H2 activation), we will target a variety of cooperative systems that will rely on the synergistic action of a MG element and a TM in close proximity. Investigating these synergistic effects will set the basis for designing more efficient systems in the search for innovative cooperative catalysis. In particular, this approach will permit the low-valent MG element to act as the activator, while the TM in close proximity may provide additional mechanistic routes for further functionalization. In the long term, we expect that our novel strategy will provide solid grounds for further developments in the vivid areas of low-valent MG chemistry and in particular in their use as catalysts for challenging transformations.


**Keywords:** Main Group, Cooperative Catalysis, Germanium
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Tri-dimensional electromagnetic modelling of melting sourves in the mantle - examples of a fast spreading center and a hot-spot'.

assistant: **Objectives**

Research objectives and content Interest in marine electromagnetic experiments measuring the electrical conductivity in the earth islarge in tile scientific community and in industry. Industry is interested in using marine EM as a l complimentary method to seismics in the search of oil and gas. Scientific interest focuses on using EM to investigate the mantle upwelling and mantle melting underneath mid-occan ridges and hot-spots. Mantle upwelling is not understood due to the lack of data on the thermal state and the degree of melting of the mantle, parameters to which the electrical conductivity is particularly sensitive to.During my Ph.D. I derived the first indications of a 2D melt distribution underneath a mid-ocean ridge. Sufficient data to allow 3D imaging are now within reach. A large data set was collected on the East Pacific mid-ocean ridge in a international effort in which the host institution participated. Furthermore the host institution collected data above a hot-spot close to the Society Islands. We plan to derive and compare first AD conductivity images of the mantle upwelling zone underneath a hot spot and a mid ocean ridge based on the data sets provided by the institution which also supplies and develops 3D modelling and inversion software. Training content (objective, benefit and expected impact) Universite de Bretagne is currently the only institution capable of performing deep penetrating EM experiments. The TMR progranm would allow me to work on a unique set of data and learn about 3D modelling of marine EM data. Deriving 3D images with the help of data and software supplied by the host institution would yield first observational 3D information on the mantle upwelling which is of fundamental interest for earth sciences. Performing the research at t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Genetic polymorphisms and biomonltorlng of styrene', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

So far, biological monitoring methods and biological limit values applied in occupation- tonal and environmental medicine have been developed on the assumption that individuals do not differ in their biotransformation capacities. It has become clear, however, that this is not the case but wide inter-individual differences exist in the metabolism of xenobiotics. Integration of the data on individual biotransformation capacity in bolo- goal monitoring studies is anticipated to represent a significant refinement of the currently used methods. Consequently, the main goal of the present project is to clarity the potential role of the polymorphisms in CYP2EI, EPHX, GSTM1, GSTP1, and GSTT1 genes in modifying individual responses to styrene, as measured by urine metabolites, adducts in blood macromolecules, and cytogenesis alterations in lymphocytes. It also aims to de- flop alternative methods to assess CYP2E1 phenotype and to clarify the still unclear correlation between peroxide hydrolyse genotypes and phenotypes.The results achieved so far clearly indicate that GSTM1 genotype is an important modifier of urinary PHEMAs excretion, and that the mechanism by which GSTs catalyze GSH-conjugation of SO in humans is regio- and stereo-selective. The [R,R]-M1 is the main mercapturate affected by the GSTM1 genotype and it accounts, in the GSTM1 positive subjects, for 56% of total PHEMAs excreted during 24 hours following styrene exposure. Although less significant than that of GSTM1, an involvement of GSTT1 in the formation of PHEMAs is also possible. The influence of this genotype was specifically noted for the [R,R]-M2 metabolite, further illustrating the regio- and stereo-selectivity of GST activity on SO. A modifying role of GSTM1 and GSTT1 was also found regarding the induction o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'An in vitro 3D microfluidic human NeuroVascular Unit model for identifying the cell-type-specific responses to diverse inflammatory stimuli in the brain capillaries', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Neurological disorders affect many people's life, contributing to significant mortality and morbidity in the modern world, with 16.5% of global deaths and are the leading cause of disability, affecting 276 million people's daily lives. Many of these diseases, including Alzheimer’s and Multiple Sclerosis, are related with the impaired blood-brain barrier (BBB) function. Unfortunately, neither animal models of the neurovascular unit (NVU) nor in vitro cultures of primary or immortalized human brain microvascular endothelial cells (BMVECs) alone effectively mimic the barrier, and transporter functions of the BBB observed in humans. Thus, there is a great need for human NVU models to recapitulate in vivo human physiology in health and disease conditions and understand the cellular mechanisms and changes in disease conditions. This project aims to develop a 3D NVU model to identify the cell-type-specific responses to diverse inflammatory stimuli in the NVU.The NVU-Chip project will the first model providing such a complex cellular environment in a unique microfluidic device to fully recapitulating human NVU in vitro utilizing relevant mechanobiological forces. Additionally, The NVU-Chip will improve the state-of-the-art by incorporating cyclic mechanical strain in a BBB model for the first time. This project will combine and amend the state-of-the-art stem cell technologies to differentiate all brain cells, and advanced microfabrication approaches to design and fabricate the microfluidic chips using the most appropriate materials ECM coatings for co-culturing all cell types in the same device. The human-based NVU-Chip model will also give a new approach for studying cellular responses to diverse inflammatory stimuli, identifying key inflammatory factors of CNS related diseas
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Systems biology of liver cancer: an integrative genomic-epigenomic approach' (MODHEP) targeting Seventh Framework.

assistant: **Abstract**

Cancer is a complex disease involving multiple genetic and epigenetic events occurring, and influencing each other, over a long period of time. Understanding cancer, and ultimately developing effective targeted therapies, will therefore require that mutations and epigenetic alterations be systematically investigated during the multiple stages of disease development, from identifiable pre-neoplastic phases to overt cancer. Until now, no systematic effort has been undertaken to investigate these multiple layers of genome organization and function during cancer development. MODHEP aims at providing a 360° understanding of liver cancer, one of the most common types of tumors and, because of the homogeneity of the hepatic tissue, the most experimentally tractable one. The consortium brings together elite European scientists in the fields of genetics, chromatin regulation, genomics, liver cancer, computational and systems biology. This combination of skills will allow us to investigate and model at unprecedented resolution the chain of events leading from environmental perturbations and the occurrence of driver mutations to preneoplastic disease and cancer. Our experimental plan reflects some grounded assumptions: 1. cancer cannot be modeled without detailed information on the preneoplastic stages of disease; 2. genetic heterogeneity in humans would make systems-level modeling non realistic from a practical point of view. Both of these limitations are bypassed by the use of well-defined mouse models, followed by evaluation of the main conclusions in clinical samples; 3. many early stage driving events in cancer represent epigenetic alterations, which are invisible to classical genetic analysis, and are confounded by secondary and tertiary events in established tumors. Our app