RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Fully Optimized Root of Trust for Robust Embedded Secure Systems'.

assistant: **Innovation**

The foundation of modern cybersecurity lies in the secure boot process, ensuring only trusted and authenticated software runs on a device. By validating code integrity through cryptographic signatures, secure boot upholds the Confidentiality, Integrity, and Availability triad, acting as the first line of defense against tampering, malware, and unauthorized changes.Currently, secure boot relies on traditional cryptographic algorithms like RSA. However, the advent of quantum computing threatens these systems, as quantum algorithms like Shor’s could break them, necessitating a transition to Post-Quantum Cryptography. The European Union and relevant agencies, such as ANSSI and BSI, advocate for a Post-Quantum/Traditional (PQ/T) hybrid cryptographic model, combining quantum-resistant algorithms with traditional cryptography for added resilience. Implementing quantum-safe secure boot remains challenging due to the performance, scalability, and compliance trade-offs of PQ/T solutions. However, to date there seems no significant progress has been made in this domain.FORTRESS aims to address these challenges by developing a scalable and efficient hybrid secure boot architecture. It will design a flexible Root of Trust, integrating both traditional and post-quantum algorithms while exploring trade-offs between security, performance, and cost. The project will focus on hardware-software co-design principles, enabling diverse platforms - embedded systems, edge devices, and Critical National Infrastructure - to transition to quantum-resistant architectures seamlessly. Additionally, the project will engage industry stakeholders to align with regulatory and standardization efforts, ensuring practical deployment and maximum impact.By developing a critical building block for a wide rang
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Design of targeted gene pharmaceutics using self-assembling functional entities' in the context of a Sixth Framework call.

assistant: **Objectives**

During the last years, developments in genomics have enabled an unprecedented acquisition of new knowledge with relevance for human disease. In parallel, the biotech industry has invented novel ways of generating drugs in order to meet the demands from the healthcare sector. Here, we outline the development of a novel Gene Pharmaceutics prototype through translational research. This can be accomplished by the combined efforts of three research-intensive biotech companies together with two academic groups, representing state-of-the-art skills and proprietary technologies in complementary areas. These include nucleic acid analogue chemistry, short interfering RNA (siRNA) technology, gene transfer and gene therapy, as well as imaging instrument manufacturing, and methods for self-assembling supramolecular complexes. This will lead to the design of new self-assembling Gene Pharmaceutics and bringing them to the stage of clinical grade. The aim is to develop plasmid and siRNA-based drugs that target the liver, since this organ is affected in many disorders involving a genetic component. Three diseases have been selected for this purpose, hepatitis B and C infections and an inherited form of bleeding disorder, haemophilia A (FactorVIII deficiency). Moreover, many aspects of this platform technology are likely to be applicable to essentially any liver disorder and may also be transferable to other organs systems. Fully developed this technology could result in new, safer and more rational drugs. The objectives of the project: 1. Generation of new forms of DNA-binding synthetic compounds, which will serve as genetic glues 2. Enhancing linking chemistry for biologically active entities coupled to DNA binding compounds 3. Optimising the assembly of Gene Pharmaceutics by in vivo e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Health certification of rosaceous species based on disease-indexing of in vitro plants : validation of diagnostics and diagnostic strategies' (1994-1998).

assistant: **Innovation**

In vitro culture techniques are used for mass clonal propagation and disease elimination from germplasm of fruit tree and strawberry cultivars. However disease-indexing is carried out on the donor plants prior to culture or is based on the field progeny. On the one hand this situation results from the fact that many diseases affecting rosaceous species are of unknown etiology, thus are only detectable in lengthy and cumbersome field tests using indicator plants. On the other hand even for better investigated pathogens (viruses, phytoplasma) there exists a lack of rapid, reliable, sensitive and user-friendly laboratory methods for routine large-scale application to detect the harmful organisms. It is within the objectives of the proposed project to develop and assess broad spectrum and specific assays for detection of filamentous, bacilliform and nematode-transmitted viruses. Broad spectrum assays, which means a single test, that is able to check for the presence of a range of pathogens, including previously uncharacterized ones, are an ultimate request in certification programmes, as the primary testing purpose is to check for freedom from pathogens. Phytoplasma detection is largely based on universal and group specific primer thus the aim is to optimize and simplify existing diagnostic techniques. The methodology to be used (RT-PCR, PCR-ELISA, NASBA) is based on the amplification of the pathogen genome. Research is necessary to validate the application of diagnostics developed for plant application in vivo to in vitro material. An important aspect of this validation is to determine the influence of in vitro media and culture environment on pathogen titre in in vitro tissues. In vitro plant growth conditions that maximise titre to facilitate detection and to avoid patho
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Evolution and growth in networks of technology-based small and medium- sized enterprises (SMES) and large firms'.

assistant: **Objectives**

RESEARCH OB JECTIVES physiological traits and diseases. In contrast to its central role in physiology, biochemistry, toxicology, transplantation research, cancer research, neurobiology and other fields, the rat has lagged behind the mouse as a genetic model organism. Molecular biology has catalysed the convergence of physiology and genetics, and consequently there is an increasing need for genetic studies in the rat. In the past few years there has been very significant progress in rat genome analysis. While almost no reliable gene assignment was available in the early 80'es, some 600 rat genes have now been assigned to specific chromosomes, and a genetic map with some 650 markers is also available. Teams participating in the present project have been intimately involved in this development, contributing about half of the chromosome assignments and also to the construction of the linkage maps. Furthermore, the participating teams have developed the only existing international rat genetic database (RATMAP). Thus European teams have a strong tradition in rat gene mapping, and our proposal is to generate mapping resources and information necessary to take advantage of the rat for the identification of genes underlying traits relevant to mammalian physiology, behaviour and complex disease, such as diabetes, hypertension, susceptibility to cancer or stress, drug addiction etc. The genetic basis of such traits could be understood if the rat genome was better known. The proposed project contains two parts: mapping the rat genome on the one hand and analysis of multifactorial traits on the other. The mapping work will include: - genetic linkage work of transcribed genes,especially anchored reference loci" for comparative mapping, and of anonymous markers, using molecular method
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Quantum chemical and combined quantum mechanical/molecular mechanical (QM/MM) modelling of oestrogen biosynthesis and metabolism' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The aim of the research proposal is to study the biosynthesis and metabolism of oestrogen derivatives with state-of-the-art quantum mechanical (QM) and combined quantum mechanics molecular mechanics (QM/MM) calculations. Oestrogens play a manifold role in the correct functioning of the human body, which is especially pronounced in the case of women. Prolonged exposure to oestrogen has been shown to increase the risk of developing breast cancer due to the cumulative effect of toxic metabolites formed from oestrogens. State-of-the-art treatment of breast cancer involves inhibition of aromatase, the enzyme responsible for the last step of oestrogen biosynthesis. We intend to perform QM calculations to elucidate the factors that play a role in the cytochrome P450-dependant metabolism of oestrogens, and to rationalize the possible toxicity of oestrogen metabolites by assessing their proneness to autoxidation. Our second objective is to investigate the mechanism of the aromatization step of oestrogen biosynthesis. In order to do this we plan to carry out QM/MM calculations on the recently crystallized structure of aromatase and to investigate the feasibility of various reaction mechanisms. We expect that our results could significantly contribute to our present understanding to the functioning of this enzyme and could help in the development of the new generation of aromatase inhibitors to treat breast cancer. The research work is planned to be carried out at the HAS-BME Materials Structure and Modelling Research Group of the host institute (HAS-ORG). The European Reintegration Grant would aid the professional reintegration of Dr. Oláh to Hungary by allowing her to work independently. The grant would ensure (1) the transfer of knowledge that Dr. Oláh gained as a Marie Curie R
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'INTERCONNECTING 4 HELIX INNOVATION ECOSYSTEMS IN EUROPEAN REGIONS' (INTEGER).

assistant: **Innovation**

Focused on challenge-driven promotion of healthy living, INTEGER will bring forward three important innovations for the development of more robust, sustainable, inclusive and integrative EU innovation ecosystems: 1.The INTEGER 4 Helix Collaboratory model to implement the next generation of living labs, the ‘Collaboratories’, 2.A EU Healthy Living Collaboratory, a true network of networks’ community with capacity to work on real social, tech and business-driven projects, and 3. A new professional profile, the ‘collaber’ or ‘collaboratory manager’ as a multiplying  agent of change of these integrated innovation ecosystems. The 3 INTEGER reinforcing innovations will push fivefold breakthrough capacities for the integration of social innovation in EU innovation ecosystems: 1)Boost win-win games between business and social oriented innovations addressing common challenges. 2)Transform co-creation dynamics into disruptive and tangible new products, services or competencies. 3)Co-design jointly public innovation policies. 4)Develop capacity building of the new generation of socio-digital entrepreneurs and ecosystems’ enablers, the collabers, and 5)Devise funding and investment mechanisms for social innovation start-ups and SMEs to develop and scale up game changing innovations. Collaboratories and collabers aim to embrace economic and social-driven innovation communities across EU. As novel 3H and 4H social-business innovation integration structures, these “labs without walls”, are becoming the common open house of all kinds of innovators and entrepreneurs interested in producing new products and services that come from business or social oriented innovation. Based on a peer-to-peer approach between business-driven and social-driven innovations, INTEGER seeks to accelerate tra
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Towards reliable and safe GFR' (TREASURE) under Horizon Europe.

assistant: **Objectives**

Gas-cooled fast reactor (GFR) is considered as one of the six most promising advanced nuclear reactor technologies, supported worldwide by the Generation IV International Forum and ESNII in Europe, with concepts under development in Europe and the USA. It excels in versatility, combining very high core outlet temperatures and the possibility to close the fuel cycle, allowing for very efficient and sustainable electricity and industrial heat production, replacing burning fossil fuels. The TREASURE proposal presents a Research and Innovation Action aiming at connecting European developers of GFR demonstrator ALLEGRO (V4G4 Centre of Excellence) with expert organizations with experience in GFR and HTR research, who will utilize their unique expertise and knowledge and bring fresh ideas to the GFR development. It is divided into 6 Work Packages, four of them dealing with open research and development problems of GFRs, namely the Core operation and safety optimization (WP1), Experimental validation of the DHR concept (WP2), GFR as industrial heat and power source (WP3), Enhancing GFR safety (WP4). Dissemination and outreach activities are included in WP5, alongside with communication activities with regulators and relevant international organizations, and education and training activities. WP6 ensures smooth management and execution of the project.The main objectives of the TREASURE project are:•Further optimization of the GFR fuel design and fuel cycle.•Exploring possibilities to further reduce produced waste and to further enhance proliferation resistance in GFRs.•ALLEGRO safety concept demonstration, including large-scale experimental verification.•Optimization of operation flexibility and performance of GFRs, using intermediate heat storage system, cogeneration, and hydro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'non-structural landing gear parts made of composite' (NSLGP).

assistant: **Innovation**

The objective of this proposal is to develop, manufacture and test non-structural landing gear parts for helicopter and aircrafts based on advance carbon fiber material system, the proposal introduce the methods, capabilities and resources of IAI and CirComp to fulfill the proposal requirements such as weight reduction, low cost production, and capability of the parts to sustain in harsh environmental, This proposal include activities of improving of the automated manufacture process, weight reduction by design optimization, assembly simplification and describe the certification process, innovation activities and common aims of IAI and CirComp are also introduce .The proposal describes also the expected impact during those activities, project structure, implementation and communication activities in this project
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Imagination and Religious Credence', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Many philosophers and cognitive scientists have a habit of using the word “belief” as though it refers to a single, simple sort of cognitive attitude. But if we take empirical evidence from cognitive science of religion seriously, we will see that this habit is a source of confusion. Just as it is a mistake in astronomy to assume that Venus and the North Star are the same kind of entity because they are both “stars,” so too it is a mistake in theorizing the nature of belief to treat what I call religious credence and what I call factual belief as the same type of attitude. I have already argued in my paper “Religious Credence is not Factual Belief” (forthcoming, Cognition) that our best psychological theory of cognitive attitudes, in conjunction with psychological and anthropological evidence, will treat these two attitudes differently. The research aim of the project proposed here is to elaborate on my theoretical apparatus to produce a book-length monograph that will serve philosophers and cognitive scientists interested in religious “belief,"" and the corresponding aim for public dissemination is to make this research popularly available through essays, blogs, radio, and public debate.     I propose to write _Imagination and Religious Credence_ while in residence at the Centre for Philosophical Psychology at the University of Antwerp. This will be an important step in my career development. My career aim is to achieve a level of distinction in research that will justify (1) mentoring PhD and postdoctoral researchers and (2) directing a research group similar in structure to the Centre for Philosophical Psychology. Advancing my own research and being embedded in the Centre, which has a stellar history of developing research careers, will both be critical steps toward
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'An Optimised Genetic Algorithm to Computationally Predict a Metal-Organic Framework to Separate Helium from Methane' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Metal-Organic Frameworks (MOFs) are a class of inorganic-organic crystalline material with extremely high porosity, making them ideal substrates for the separation of gas mixtures by selective adsorption. The most significant barrier to the bottom-up design of a MOF for a given application is the combinatorial explosion of possible MOFs as the sheer number of chemical environments it is possible to create makes it highly unlikely that any naïve approach will locate a suitable one in any reasonable timeframe. The overall aim of this project is to develop a method to efficiently search the space of possible metal-organic framework structures and to use this to design a framework structure with user specified properties.To this end, we propose an optimised genetic algorithm for the guided computational design of a metal-organic framework to separate helium from methane.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'The BLOSSOM Innovative Approach based on Bankable Transformative Climate Solutions in order to Improve Sustainable Climate Adaptation and Mitigation Measures'.

assistant: **Objectives**

BLOSSOM introduces a systemic approach that links public authorities (cities-regions) with private partners (e.g., banks, insurance companies and venture capitals) to cope with the disconnections and gaps related to the adoption of bankable transformative adaptation and mitigation measures. Starting from the Communities of Practice, we will set up Living Labs, i.e. collaborative environments in which citizens, experts and other stakeholders will have the possibility to test and hone the methodology and the technologies. Innovative financing and investing schemes will be tested and assessed for the adoption of the most promising bankable solutions. BLOSSOM will follow already proven co-creation/design processes (including local communities), as well as the adoption and further adjustment of technologies that use data and collective intelligence to perform ex-ante simulation on-going and ex-post assessment in collaborative environments (digital twins and dashboards). By using AI-based tools a draft business model including a visual chart with elements describing the value proposition, infrastructure, customers, and financial elements of each investing scheme will be generated, also identifying the best exploitation form based on the nature of the results and ownership structure (e.g., creation of spin-offs, products producing and selling, licensing of products/services, patenting, etc.). Once the best business model has been selected, a preliminary Business Plan will be developed with the industrial partners being the main contributors. The bankable solutions will be demonstrated in our Front Runner Cities (Birmingham, Lisbon and Kielce), which will test the methodology and make it available for replication up to the planning stage in the Replicating case studies (Regions