RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Europe under Dictatorship: Economic Control and Law' (1998-2002).

assistant: **Concept**

The proposed conference is based upon a research project on the legal history of the 20th century, which is being undertaken by the Max-Planck-Institut für europäische Rechtsgeschichte in the period 1999-2004 in collaboration with various European partners. Adopting the perspective of the legal regulation and control of the economy, the project is devoted to an important aspect of the government of those European societies, which in the course of the century were affected by various forms of the dictatorial state. Apart from a further development of the very diverse states of research in the individual European countries, the project seeks in particular to make progress in a comparative direction. The manifest differences between the various dictatorial forms in many important respects argue against any simplistic pan-European generalisation, but not against the academic necessity of a comparative analysis. It is precisely in the area of the legally supported control of the economy that such an approach seems particularly appropriate.The European dictatorships have their roots in the fundamental crisis into which the economically liberal model of society had fallen by the end of the 19th century. The dictatorships, as control-oriented forms of political domination, can be understood as secular answers" to this crisis. The conference has the objective of analysing the scope and relevance of these "answers" in the context of selected areas of study. Insights can thereby be anticipated concerning the well-attested failure of these attempts at control, and thus also about the internal weaknesses of the dictatorships."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'An Advanced Circular and Agile Manufacturing Ecosystem based on rapid reconfigurable manufacturing process and individualized consumer preferences' in the context of a Horizon 2020 call.

assistant: **Objectives**

KYKLOS 4.0 will demonstrate, in a realistic, measurable, and replicable way the transformative effects that CPS, PLM, LCA, AR and AI technologies and methodologies will have to the Circular Manufacturing  (CM)Framework. To this end, KYKLOS 4.0 will (1) perform large-scale piloting in 7 pilots to demonstrate the technical, environmental and economic viability of KYKLOS 4.0 Ecosystem to reshape intra-factory processes and services, (2) show KYKLOS 4.0 value in terms of operational efficiency improvements by at least 15%, (3) deliver resources reusable solutions (second use of material, part and components reuse) for the whole manufacturing sectors, (4) ensure scalability for future scale of novel CM technologies and services at least at the level of year 2024, (5) engage over 100 key European industry actors, (through open calls and workshops) (6) transfer knowledge and technology to increase use of KYKLOS 4.0 Ecosystem to at least 50%, (7) strengthen the position of EU CM technologies providers and sector fostering a market share of up to 12% (8) pursue a strong plan for sustainability by incubating at least 3 post-project replication sites, (9) mobilize additional sector investments of at least 6 times the EC contribution.Bringing together knowledge and solutions of major European CPS, PLM, LCA and AI technology providers together with the competence and experience of key European industry players in the CM domain, KYKLOS 4.0 will demonstrate a measurable increase of KYKLOS 4.0 Ecosystem penetration in CM market, reduction of environmental impact due to the reduce of the use of fossil fuels and raw materials and impact in seven pilot domains, which cover areas of major importance for the CM sector in EuropeA unique characteristic of KYKLOS 4.0 is that all CM related tec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'OPTIMIZING THE IMPLEMENTATION AND SCALE-UP OF THE WHO TB TREATMENT DECISION ALGORITHMS FOR CHILDREN WITH PULMONARY TUBERCULOSIS IN SUB-SAHARAN AFRICA'.

assistant: **Concept**

Every year, about a million children under 15 years are diagnosed with Tuberculosis (TB) worldwide, and about a quarter die. However, over 60% of children with TB remain undiagnosed, particularly in sub-Saharan Africa, which accounts for about 20% of the global burden of paediatric TB cases. In 2022, WHO issued an interim general recommendation to use integrated Treatment-Decision Algorithms (TDAs) to diagnose TB in children under 10 years. However, this recommendation was based on very low certainty of evidence. Therefore, we are seeking funding to address four objectives: 1) To compare the effectiveness of TDAs and the Standard of Care in routine clinical settings 2) To identify processes and contextual factors that influence the effectiveness and fidelity in the implementation of TDAs 3) To compare the costs, cost-effectiveness, and the population level impact of the TDA strategies on the burden of TB and 4) To validate the diagnostic performance (sensitivity, specificity, negative and positive predictive values) of the TDAs in various health system settings and clinical context. A four-year pragmatic open-label cluster randomized controlled trial will be conducted in 120 primary health facilities in Tanzania, Uganda, and DR Congo. The primary outcome is the proportion of children detected and initiated on TB treatment. About 60,000 children with presumptive TB will be screened. We anticipate that this project will yield results that address the issue of low detection rates of paediatric TB in sub-Saharan Africa and beyond, build research capacity in conducting implementation research in low-income countries, and foster networking and collaboration between the partner institutions.


**Keywords:** Cluster randomized controlled trial
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'South American Permo-Triassic Fish Fauna Turnover and its Bearing on the Mass Extinction Scenario' (2002-2006).

assistant: **Innovation**

Global extinctions, their causes, duration and recovery phases are still disputed on the basis of localized palaeontological and geochemical evidence. The greatest mass extinction allegedly affected 70-90 per cent of animal and plant species worldwide at t he P-T boundary (PTB), approximately 250 million years before present, but has been poorly studied in South America.This multidisciplinary project seeks to investigate key strata from that continent in order to gather palaeontological and geochemical data on fishes, subsidiary taxa and stable isotopes, focusing on the presumed turnover of fish faunas and drastic environmental changes near this boundary in that region.In particular, the evidence and implications of distinctive palaeoenvironments in association with bone-beds such as large, shallow epicontinental Gondwanan seas and the sediments in the vicinity of the PTB Araguainha impact crater in Brazil will be investigated in detail. Published records on fauna and environment from the Northern and Southern Hemisphere will be re-assessed, compared with the newly available South American data and evaluated with respect to the purported global extinction event.The project will be based at the Natural History Museum (London), which houses most of the sample s and expertise. Together with the partners in this project, all analytical facilities necessary for its successful completion, will be in place. The Applicant will develop collection management skills by databasing newly collected materials. He will investigate PTB fish faunas and perform faunal studies using detrended correspondence and cluster analyses.In order to diversify his career in research, he will be introduced to methodology and techniques in Scanning Electron Microscopy, stable isotope geochemistry and b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Developments in finsler geometry dynamical and metric aspects' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

My research project will be carried out at the department of mathematic at Manchester University in the group of Ergodic Theory and Dynamical Systems, and is centered on the three following points:  - the problem of minimal topological and volume growth entropies for Finsler metrics on a Riemannian hyperbolic compact manifold M with both normalisations by the volume of M and by Liouville's volume of the sphere bundle;  - the problem of minimal topological entropy for Finsler metrics on a locally symmetric Riemannian compact manifold of the non compact type with rank>l;  - the study on a compact manifold, from the Finslerian point of view, o the negatively curved Riemannian metrics for which Bowen-Margulis and Liouville measures coincide.  These questions, which run straight on from my Ph. D. thesis, will brin to me a wider competence in my own area (Finsler geometry) together with a fresh knowledge in the field of dynamical systems.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Virtual Anthropology of Prehistoric Portugal' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The VAPP Project will examine prehistoric human population dynamics and microevolution in Portugal through the analysis of dental morphological variation. Variation in external dental morphology (e.g., size, shape, and discrete characteristics) provides reliable data on biological affinity and relatedness within and between human populations, as well as signatures of selection on dental functional morphology related to different diets and masticatory regimes. Advances in non-invasive, virtual imaging technology provide complimentary, high-resolution data on internal dental morphology (e.g., enamel thickness, tissue proportions, enamel dentin junction shape) that address key aspects of dental morphological variation and evolution. Nevertheless, few studies have focused on how internal dental morphology varies among human populations during the Holocene, and only one Homo sapiens dentition from Portugal has been virtually analyzed to date. The prehistory of Late Pleistocene to Mid-Holocene Portugal is characterized by complex environmental, climatic, and demographic changes that significantly altered socioeconomic organization, thus making it an ideal regional case study to address human biocultural evolution through an integrated approach to internal and external dental morphology. The VAPP Project will include Upper Paleolithic humans, the last foraging populations (Mesolithic), early food-producing peoples (Neolithic), and groups associated with the emergence of social complexity and the intensification of food processing (Late Neolithic, Chalcolithic, and Bronze Age). The sampling strategy provides a nuanced perspective on dental microevolution corresponding to changing diets, socioeconomic strategies, and spatiotemporal population dynamics (e.g., migration, integrati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Integrated development and operations management framework for cyber-physical systems of systems under the paradigm of swarm intelligence' (1-SWARM).

assistant: **Concept**

Recent years have seen the widespread diffusion of low-cost computational systems, triggering the transition towards even further decentralization towards the Edge of autonomic intelligence. While in the consumer domain this transformation is happening very fast, industrial applications are inevitably more conservative and require solid methodological and technological grounds to guarantee this transition to be dependable.1-SWARM project focuses on the design-operations for CPSoS with the specific focus on industrial sector of large-scale distribution and logistics. The project aims at achieving industrially acceptable level of robustness of CPSoS whose operation emerges as “Swarm Intelligence”. 1-SWARM’s solution will span across different steps of the value chain, connecting intelligence through the digital domain to maximize their effectiveness and reliability. The objective is to provide a methodological and technological framework, modular and re-usable (“Swarm Intelligence DevOps Framework”), for the engineering of the three major aspects of CPSoS: i) The HW/SW runtime platform that sustains their operations; ii) The distributed and orchestrated Intelligence that guarantees their autonomic behavior; iii) The extension of their “existence” into the cyber-domain for a full life-cycle approach.Key to the exploitability of 1-SWARM’s result is the demonstration of its potentialities for 4 different application scenarios, whose requirements come from cross-domain use-cases, whose variability allows extensive validation of the project technologies: 1) Manufacturing CPSoS for food packaging; 2) Logistics CPSoS for reconfigurable material handling; 3) Fleets of intelligent AGVs in complex dynamic environment; 4) Aerial drones flock for extensive monitoring of retails shops
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Noise control trims for liquid and gas flow in pipe lines within existing or close to control valves' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

Valves for high velocity fluid pipelines are used extensively throughout the process and power industries. However, when utilising them to implement flow control, the intrinsic pressure differentials created between the valve inlet and outlet can cause cavitation(in liquid systems) and high flow turbulence(in gas systems). Cavitation not only leads to serious boundary erosion but also vibration and objectional noise is observed. The energy used to throttle the flow in gas systems dissipates to form the aforementioned turbulence which is subsequently converted ill acoustic energy. This propagates down the length of the pipe and results in high levels of noise and vibration. The project seeks to research the basis for the development of a variable noise suppression system for high velocity fluid valves that, by adjusting the configuration ot the valve during operation, can deliver the requisite levels of attenuation in noise and vibration for a range of upstream pipe velocities and pressure differentials. Achieving this will help to substantially reduce the risk of premature failure. The project can be split into the following areas; a) advanced fluid dynamic techniques and comprehensive experimental testing, research into novel valve and baffle configurations to establish the requirements necessary to create a system capable of delivering the proposed variable noise suppression. b) Confirmation of the valves performan through extensive field testing under a range of valve velocity and pressure differential conditions. The main problems will lie in developing a valve geometry that is capable of delivering the same noise compensation over a large range of flow and pressure conditions. The research must show that the new development can improve on existing v alve designs by
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Multiscale Integrative Approach for Corneal Biomechanics to Assess Corneal Crosslinking' under Horizon 2020.

assistant: **Concept**

Approximately 250 million people worldwide are visually impaired, and this has great economic and social impact. One of the pathologies of vision loss is keratoconus, in which the mechanical balance of the cornea depending on intraocular pressure and internal stresses in corneal tissue becomes imbalanced, which can result in a corneal protrusion.Corneal crosslinking (CXL) is a clinical treatment that increases the overall mechanical stiffness of the cornea by inducing chemical bounding between collagen molecules. CXL is the present of halting corneal ectasias, and the future of noninvasive refractive surgery. However, its micro/nano-mechanisms are not completely understood. Moreover, CXL is usually applied uniformly in corneal treatments, which can result in over-stiffening and unexpected postsurgical outcomes.Ophthalmology can benefit from in silico modeling to plan and improve such interventions. However, current computational models are mainly macroscopic and cannot simulate complex phenomena involved in CXL. Multiscale computational models could improve clinical strategies by including information at different scales.MIMetiCO’s goal is to combine experiments and modelling at different scales to provide a multiscale characterization of corneal biomechanics before and after CXL. This characterization will rely on both ground-breaking and well-established technologies that include confocal microscopy, biochemical assessment, and mechanical inflation tests to determine morphological (orientation and density of fibrils), biochemical (amount of intermolecular crosslinks), and mechanical features of the cornea.MIMetiCO will use this information to calibrate the first in silico model of the cornea using a multiscale structural approach to build a virtual framework to simula
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Etox10'.

assistant: **Objectives**

The aim of this project is to organize a European Workshop devoted to the comprehension of the mechanisms underlying the activities of bacterial protein toxins that are main virulence factors in bacterial associated-diseases. The workshop organized in 2001 is the 10th edition of a series of workshops organized on that topic every two years. The questions that will be addressed in this workshop are closely related to challenges that we will have to face in the near future: the high cost of infectious diseases both in terms in mortality and public health and the need for alternative strategies of treatment because of the rapid increase of of multi drugs resistant bacterial strains.This meeting will bring together scientists working in different fields (from biophysics to cell biology) of fundamental research with scientists working in industry and in international health organization. The structure of this meeting is intended to create many fruitful interfaces between leading scientists and young researchers. The main area that will be covered at this meeting are as follows: Regulation and Genomics, Rafts and Receptors, Structure-Function of Toxins, Cell Biology of Toxins, New issues and Applications of Toxins, Complex delivery systems.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Empowering and participatory adaptation of factory automation to fit for workers' to be submitted under Horizon 2020.

assistant: **Abstract**

Smart factories are characterized by increasing automation and increasing customization. In these dynamic environments flexible and adaptive work organization is crucial both for productivity and work satisfaction. Factory2Fit project will support this development by developing adaptation solutions with which people with different skills, capabilities and preferences can be engaged, motivated and productive members of the work community in manufacturing industries. The core idea in Factory2Fit project is that the worker is an expert of his/her own work and thus (s)he shall have an active role in designing his/her work. The proposed adaptive automation solutions are based on a dynamic user model that includes physical and cognitive abilities. The worker him/herself gets feedback of his performance and skills, which supports continuous learning and competence development. Virtual factory models will be used as engaging platforms for participatory design of work practices, knowledge sharing and training, involving all the relevant stakeholders in contributing the organizational development. Contextual guidance and knowledge sharing is supported by augmented reality based tools. The adaptation solutions will be developed within three industrial pilots in actual manufacturing environments. The solutions will be generalized and disseminated widely to the manufacturing industry.  Adaptive automation solutions to be developed in Factory2Fit will support fluent human-automation cooperation and will have impacts in work satisfaction, less occupational health issues, less stress, better ergonomics, better quality, less errors and better productivity. Adaptive automation supports current and forthcoming workers to develop their competences towards knowledge workers of smart factori