RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Multi-layered biomimetics of lytic polysaccharide monooxygenases' to be submitted under Horizon 2020.

assistant: **Abstract**

The high stability of components like cellulose limit the efficiency and cost effectiveness of biofuel or chemical production from lignocellulosic biomass. Thus, the ability of the recently discovered class of metalloenzymes, lytic polysaccharide monooxygenases (LPMO), to enhance the efficiency of recalcitrant polysaccharide degradation makes understanding these enzymes invaluable for carbon friendly sustainable  chemical and energy development as prioritized under the Horizon2020 program. The current project seeks to develop multi-layered biomimetics of the LPMO active site that can offer unprecedented replication first and second coordination sphere groups, in order to be able to rationally study the collection of interactions that contribute to enzyme activity.  The research involves the design and chemical synthesis of aromatic oligoamide scaffolds that incorporate a specific copper binding site. Through synthetic modification of the scaffold to alter the second coordination sphere, and combined spectroscopic and electrochemical methods, changes in the properties and reactivity of the metal site will be studied with a goal of developing a structure- function relationship that can assist in guiding enzyme modification, as well as, new synthetic catalyst development.The applicant has a strong background in synthetic chemistry and mechanistic studies that will be crucial to the success of the project. Through joining the host lab in Belgium that specializes in coordination and supramolecular chemistry, she will greatly increase her own knowledge base, while transferring her knowledge of synthetic organic chemistry to the host. Additionally, during proposed secondments to work with a collaborator in Germany for the electrochemical studies, the applicant will further exp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Monitoring the immune response mediated by cd4+ t cells in vaccinated cancer patients.'.

assistant: **Concept**

There is no sensitive and reliable method to monitor the immune response in the cancer patients vaccinated with a protein or with peptides presented by HLA class II molecules. We will therefore analyse in responding patients if we find a difference in terms of number, specificity, or diversity between anti-MAGE-3 CD4+ T cells before and after vaccination.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Innovative technologies and concepts for fine particle flotation: unlocking future fine-grained deposits and Critical Raw Materials resources for the EU' (FineFuture) under Horizon 2020.

assistant: **Objectives**

Froth flotation is arguably the most important mineral separation technique. By making use of differences in surface properties between  minerals, valuable particles are concentrated in large tanks by attaching to bubbles, which form a froth phase that overflows as a mineral-rich concentrate. However, current flotation technologies do not work adequately for fine particles, below 20 µm in size. This is a serious challenge at present limiting the exploitation of deposits and proper recycling of end of life products containing Critical Raw Materials (CRM). This FineFuture project will advance the fundamental understanding of fine particle flotation phenomena, which will lead to the development of ground-breaking technological solutions. This will not only help unlock new CRM deposits but also contribute to increase the resource and energy efficiency of current operations where the fines are lost to tailings. FineFuture will also enable proper reprocessing of old tailings deposits and be technology-transferred to other raw material particle-based processes within the circular economy, thus leading the way in the sustainable use of resources. For the EU industry the ability to float fine particles will be fundamental in securing access to raw materials in the future, yet to date there is no large scale collaborative effort to achieve this. The FineFuture consortium brings together an industry- and user-driven multidisciplinary team with the skills and experience required to tackle the challenging objectives set up for this project. Through a first of its kind research approach, the consortium’s combined expertise in science, engineering and industrial practice will allow a robust and knowledge-based development of innovative fine particle flotation technologies. This projec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Computing Veracity Across Media, Languages, and Social Networks' (PHEME).

assistant: **Concept**

Social media poses three major computational challenges, dubbed by Gartner the 3Vs of big data: volume, velocity, and variety. Content analytics methods have faced additional difficulties, arising from the short, noisy, and strongly contextualised nature of social media. In order to address the 3Vs of social media, new language technologies have emerged, e.g. using locality sensitive hashing to detect breaking news stories from media streams  (volume), predicting stock market movements from microblog sentiment (velocity), and recommending blogs and news articles based on user content (variety).<br/>PHEME will  focus on a fourth crucial, but hitherto largely unstudied, challenge: veracity. It will model, identify, and verify phemes (internet memes with added truthfulness or deception), as they spread across media, languages, and social networks.<br/>PHEME will achieve this by developing novel cross-disciplinary social semantic methods, combining document semantics, a priori large-scale world knowledge (e.g. Linked Open Data) and a posteriori knowledge and context from social networks, cross-media links and spatio-temporal metadata. Key novel contributions are dealing with multiple truths, reasoning about rumour and the temporal validity of facts, and building longitudinal models of users, influence, and trust.<br/>Results will be validated in two high-profile case studies: healthcare and digital journalism. The techniques will be generic with many business applications, e.g. brand and reputation management, customer relationship management, semantic search and knowledge management. In addition to its high commercial relevance, PHEME will also benefit society and citizens by enabling government organisations to keep track of and react to rumours spreading online.<br/>PHEM
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'PICSOHF, A minimally invasive cardiac intervention medical device to regenerate a damaged heart and extend the life of patients with Heart Failure' (PICSOHF) targeting Horizon 2020.

assistant: **Abstract**

Worldwide 26 million people live with HF (Heart Failure) which is a major burden, not only for the patient, but one that also threatens the sustainability of national healthcare systems. Despite advances in treatment solutions over the last 30 years, improvements have not met the expectations for cardiac recovery and prognosis following heart attack. Current treatments are only partial solutions as they cannot regenerate the damaged heart tissue, and are thus unable to stop the progressive loss of heart function, low short- and medium-term life expectancy, and impoverished quality of life due to co-morbidities and/or frequent and continuous re-hospitalisations. Regenerative concepts, such as cellular therapies to regain cardiac function, once of the greatest hope for heart failure patients, have been recently discredited as they have been unable to show scientific proof of efficacy. Miracor, developed and clinically tested PiCSO, a breakthrough cardiac intervention triggering myocardial regeneration. Our therapy consists of a percutaneous right heart catheter intervention using proprietary software for feedback control that temporarily elevates the pressure in cardiac veins reactivating innate regeneration pathways. We have tested PiCSO in chronic HF patients (8 patients versus 22 controls) and demonstrated that 30 minutes of intervention changed the pattern of regenerative biomarkers in cardiac veins that resulted in significantly improved survival at 10 years follow up. Our patented technology (PiCSOHF ) is changing the market in HF, as no similar device is currently available. Our strategic goal is to become Europe´s leading reference in treating HF. After full technological, clinical and commercial development, PICSOHF profits will increase by +€66M within 5 years a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Cloud-based Building Information Modelling' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Building Information Modelling (BIM) as a product and process enables stakeholders across the built environment sector to create digital versions of real world assets (such as buildings, bridges and tunnels). The digital versions are commonly called 'digital twins'. When placed on the cloud, the digital twins can serve as a resilient and integrated repository of all asset data throughout their life-cycle. Such a repository is  a key enabler in this sector of all upcoming IT waves, such as cloud computing, data analytics, participatory sensing, and smart infrastructure. The potential benefits have attracted interest from a wide array of end-users whose interests span from early design phases to operation and asset management, and from roads and bridges to industrial off-shore facilities. This has led to aggressive market penetration in the last decade. However, the full potential of BIM is currently exploited only in a fairly narrow range of applications. This is mainly due to the lack of trained scientific personnel capable of understanding the value of BIM and creating the link between digital twins and possible applications. The ambition of CBIM is therefore to educate researchers in the development of a set of novel and disruptive BIM technologies that will automate the generation and enrichment of digital twins, improve the management, security and resilience of BIM-enabled processes, and boost the industrial uptake of BIM across sectors and disciplines by training these researchers to valorise and exploit their work. This new generation of researchers can play a key role in the widespread implementation of BIM products and processes dedicated to digitising our built infrastructure and managing our assets better to yield massive gains in sustainability, productivity
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Reconstructing fragmented bones, reconstructing fragmented lives' (RECONSTRUCT) under Horizon Europe.

assistant: **Objectives**

Human skeletal remains can offer key information on diverse aspects of past life but, like all archaeological materials, they only give a glimpse into the life of past individuals; hence, a fragmented perspective into our ancestors’ lives. Their interpretative potential is greatly inhibited by the fact that such remains are often found fragmented due to several anthropogenic and natural taphonomic agents, such as funerary treatment, animal activity, soil pressure and others. This fragmentation severely limits the information that may be extracted from human bones in terms of metric analysis, geometry and morphology. RECONSTRUCT aims at producing 3D morphable models for the main elements of the lower and upper limbs of the human skeleton, which will be then used to infer the missing morphology of fragmented or incomplete bones. In order to achieve this aim and address a major current limitation in human skeletal analysis, RECONSTRUCT will integrate approaches from osteoarchaeology, forensic anthropology, biology, engineering, and data science. The results of the project will maximize the information that may be extracted from bioarchaeological research, contributing to a more comprehensive assessment of past life parameters. RECONSTRUCT will also have major implications in forensic anthropology since the study of modern skeletal remains suffers from similar limitations in terms of partial preservation as those witnessed in archaeological bones. Finally, the source code and raw data emanating from RECONSTRUCT will be made open access, greatly enhancing the extension of this approach to zooarchaeology, palaeoanthropology, and the prosthetic implants industry.


**Keywords:** Bioarchaeology,  Forensic Anthropology,  Human Osteology
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Advance co-packaged optics enabling high-efficiency cloud computing'.

assistant: **Objectives**

ADOPTION works toward the goal of proving a low power and low cost solution for intra-data centre networks employing co-packaging of the optical (CPO) transceivers with the packed switch chip. Hyperscale data centres are a fundamental and inextricable part of our digital society. However, data centre power consumption represents a huge global problem accounting for 1% of the global power consumption. Scaling the capacity of the current architectures for intra-data centre networks is also becoming more and more challenging due to the increasing power consumption of the electrical interconnects between electrical packet switches and pluggable optical transceivers.ADOPTION aims at addressing switch capacities scaling beyond 204.8Tb/s with port speeds of 6.4Tb/s by reducing the electrical interconnect lengths using silicon photonics CPO transceiver engines with high power efficiency targeting around 3pJ/bit. ADOPTION will also develop innovative packaging solutions using a two-part assembly separating the electrical and optical layers to simplify processes and increase yield. An advanced active optical alignment for fibre arrays will also be integrated in the assembly process with the aim of reducing assembly time and improving coupling efficiency. With these solutions ADOPTION is targeting the challenging goal of reducing the cost of the optical interfaces to below 50 cents per Gb/s. ADOPTION will also demonstrate disruptive new network architectures for hyper-scale data centres and AI computing clusters utilising optical switching and routing to increase efficiency and reduce latency.ADOPTION is aiming to create a new ecosystem of research and innovation, building on the complementary expertise of 3 SMEs, 3 large companies and 4 research institutions in the consortium, an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Magnetic imaging of individual nanomagnets' (NANOMAG-SQ).

assistant: **Innovation**

Magnetic nanoparticles have a number of present and proposed applications in biology and medicine, such as bio-separation, drug delivery, magnetic resonance imaging and hyperthermia cancer treatment, as well as important role in future high density data storage and spintronic devices. Therefore, there is high interest and strong need to characterize them properly. So far the common characterization method has been to measure a large number of them together in order to accumulate sufficient signal. This is problematic because the magnetic properties of nanomagnets are inherently sensitive to small variations in volume, shape and structure, and this strong variability is averaged in the bulk. It is therefore vital to characterize nanomagnets individually. Successful experiments are rare and required extensive efforts to characterize one single particle. I propose to use a scanning SQUID with sufficient sensitivity and spatial resolution to detect an individual nanomagnet and use the scanning capability to sample many individuals to gain statistics about the variability of their physical properties. In addition to establishing a breakthrough characterization tool, I plan to address physical questions of interest such as the nature of the interactions between small numbers of particles, the dynamics of these particles and the distribution of physical properties. To accomplish this we need an extremely high moment sensitivity, sufficient spatial resolution, minimal magnetic influence of the probe on the particle, and access to various temperatures. These requirements point to the SQUID as an ideal candidate for this task. In the framework of this grant I plan to investigate two types of nanomagnets: FePt particles, which are candidates for biomedical applications; and CoFe d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'A joint music making game augmenting social skills in autistic individuals' (AUTISMUS).

assistant: **Innovation**

Autism Spectrum Disorder (ASD) is a condition marked by communication difficulties, but some individuals with ASD excel in understanding and responding to music. Joint musical activities have shown promise in improving social behavior among people with ASD. However, existing music-based interventions have limitations: they lack precise control, flexibility, and accessibility, often requiring training or therapist presence. To address these issues, the AUTISMUS project aims to create technology that allows ASD individuals to easily access engaging and interactive musical activities, even from home. This project leverages a pillar of my ERC StG – the eMusic Box (eMB) – a device developed to enable non-musicians to make music together, mutually adapting to each other’s performance. We will assess if individuals with ASD can use the eMB effectively and whether it enhances their social functioning. If successful, we plan to bring this technology to market, considering insights from end-users. The eMB's impact spans various stakeholders, including individuals with ASD, caregivers, educational institutions, healthcare professionals, therapy centers, research organizations, and autism support groups. Its versatility suits ASD individuals of different ages and abilities. Compared to existing technologies, the eMB offers superior accessibility, flexibility, and interactivity. Our exploitation route involves patenting the technology and licensing it to a market leader for broad distribution to both B2B and B2C customers, fostering innovation and enhancing global products and services.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Automated Diagnosis for Helicopter Engines and Rotating parts' in the context of a Sixth Framework call.

assistant: **Objectives**

Helicopters availability, in-flight reliability and low cost maintenance are major concerns for helicopters operators. HUMS (sensor based health monitoring) is an enabling technology seeking to provide a Condition-Based Maintenance (CBM)  relying on automated diagnosis / prognosis for aircraft components health. Challenges for HUMS are to implement automated low cost CBM systems, as an alternative to periodic physical inspections. Existing  HUMS technologies tend to generate  high rates of false alarms due to use of fixed alarm thresholds. Automated software analysis of fleet operating data recorded by on board sensors is a major scientific direction to reach adaptive , reliable, and low cost HUMS systems.   The ADHER R and D project will improve HUMS performances in 3 directions :  1) Include simultaneous Oil Debris Monitoring (ODM) and Vibrations monitoring, using available ODM and Vibrations sensors 2) Analyze new physical models for ODM and Vibrations characteristics of helicopter rotating parts (gearboxes, bearings, etc.) to calibrate ageing effects and progressive emergence of failures 3) Conceive and validate innovative softwares dedicated to Auto-Adaptive Diagnosis / Prognosis of rotating parts potential failures for helicopters. Based on Self-Learning Algorithms, these softwares will analyze helicopters fleet data and their time evolution.  New physical models and  Automatically Learned functional relationships will improve links between sensor recorded features, helicopter usage,and regime characteristics.  The project main goal is to enable fleet scale" health monitoring, with robust failure diagnosis / prognosis, relying on multi-sensors monitoring , and automated software analysis of sensor recorded data.  This will reduce false alarms rates and maintenance