RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'The basis of inaccessibility induced in cereal epidermal cells'.

assistant: **Innovation**

The terms induced accessibility" (IA ) and "induced inaccessibility" (ll) have been adopted to describe situations where early attacks increase susceptibility or resistance, respectively , to later attacks. II is extremely effective, race non-specific and persistent. However the molecular basis of IIis unknown. If we can understand the basis of induced changes, we may be able to modify the plants intrinsic ability to resist disease by enhancing constitutive expression of factors that are normally expressed only after induction of inaccessibility, The current proposal aims to identity the basis ofII in relation to powdery mildew, one of the most damaging diseases of temperate cereals. The primary objective will be to understand the biochemical basis of II to B. graminis by using chemical inhibitors to disrupt host metabolic pathways known to influence resistance (AOA,OH-PAS, DDG, Mannose, Cicloheximide and Cytochalasin. Additional experiments will examine whether oat crown rust attack (on mespophlly cells) induces changes in epidermal cell response to powdery mildew attack. This will explore the possibility of cross-talk inducing changes between different plant leaf tissues. The applicant will benefit directly from acquiring a detailed understanding of the biology of host resistance and Jeaming biochemical and histological analytical procedures to elucidate complex interactions using light and electron microscopy. Whatever the outcome of individual experiments using inhibitory chemicals, the results will definitely provide valuable information on the basis of induced inaccessibility. The host look forward to applicant bring her skills to help our research. The problem she wishes to study is of great interest to the Group. The proposed study will further our understanding
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Health Equity and its Economic Determinants (HEED): A Pan-European Microsimulation model for Health impacts of Income and Social Security Policies' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Economic determinants, such as income and employment, are key drivers of population health and health inequalities, but have rarely been included in modelling studies to inform policy. This innovative project will develop the Health Equity and its Economic Determinants (HEED) model to investigate the impacts of taxation and social security policies on population health and mortality across Europe. There are 4 phases: 1) creating effect estimates for model inputs, 2) developing the model, 3) trialling policy simulations in one European country (UK), and 4) Europe-wide policy simulations. In phase 1, we will use causal approaches to analyse longitudinal data (the UK Household Longitudinal Study and Swedish registers), to estimate effects of changes in household income and employment status on health status (SF-12), mental health (GHQ-12 and psychotropic medications), life satisfaction and all-cause mortality. In phase 2, we will build a microsimulation policy model based on a representative synthetic UK population. We will develop projections for one, five and 10-year time periods, accounting for pre-existing demographic, epidemiological and economic trends. We will validate HEED by comparing projections with data not used in model construction. In phase 3, we will model the health equity impacts of alternative income tax and social security policies, developed with policymakers. Probabilistic sensitivity analyses will test key model assumptions and uncertainties. In phase 4, we will adapt the microsimulation model for implementation across a further 23 European Union countries. We will populate the model using available survey and demographic data to study impacts on levels of and inequalities in all-cause mortality, self-rated health, depression (PHQ-9) and life satisfa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'TWINNING FOR EXCELLENCE TO STRATEGICALLY ADVANCE RESEARCH IN CARCINOGENESIS AND CANCER' (CutCancer), addressing dissemination and exploitation.

assistant: **Impact**

The CutCancer project aims to strengthen and increase the research and innovation capacity and excellence of the National institute of Biology (NIB) in Slovenia. This will be achieved through targeted twinning activities with three internationally renowned institutions; Swansea University from the UK, Stockholm University from Sweden and VU Medical Center Amsterdam from the Netherlands, all of which poses specific, unique and complementary knowledge and expertise that is highly desired and needed at NIB. Together with ongoing substantial infrastructural improvements and significant research equipment upgrades, CutCancer will enable implementation of cutting-edge approaches and methodologies (including advanced in vitro 3D cell models, spatial and single-cell analyses), facilitating frontier research in the field of preclinical 3D cancer research. CutCancer will encompass the development of synergies between research institutions, fostering networking and participation in future Research and Innovation processes. CutCancer aims to go beyond the purely scientific aspects and raise the management and administrative capacity of NIB to reach top level. Twinning activities will include specific hands-on training, expert visits, webinars, workshops and summer schools, job shadowing and exchange of best practices, targeting strategically selected research and administrative areas. Results will be disseminated at international and regional conferences and targeted events for relevant stakeholders ranging from the scientific community to the health sector, professional networks, students and general public. The CutCancer´s strategic action plan will ensure that the project leads to long-term collaborations within the consortium and beyond. This will include future research projec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Institutional foundations of economic and political developments in post-communist countries', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

The project will explore the process of institutional change in transition economies, analyze the determinants of this process, and in particular the mutual interactions between institutional change, economic performance, and political developments during transition.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'An Intersectional Analysis of Ancient Jewish Travel Narratives' (ANINAN).

assistant: **Innovation**

ANINAN investigates literary and cultural representations of travel and mobility  the often temporary move of a person from her or his home to another location  in ancient Israelite/Jewish narratives, including selected texts of the Hebrew Bible and other Jewish writings from the Hellenistic and early Roman eras (ca. 300 BCE  100 CE). The sources, which originate from different parts of the Mediterranean region, are written or preserved in Hebrew, Aramaic, Greek, Latin, and Geez.The aim is to understand how human mobility was perceived and/or imagined in Jewish antiquity, including its agents, motives, and outcomes. The main objectives are: (1) to produce a series of case-studies that illustrate the portrayal of human mobility and its social confines in Israelite/Jewish literature; and (2) to compare and theorize the cultural representations of travel in an intersectional frame and, as a result, to provide a ground-breaking interpretative framework for the study of mobility in texts from the human past. The selected intersectional approach is novel and specifically unearths questions of power and social stratification that evidently pertain to (in)voluntary forms of mobility, including the individual profile of the traveller and the social realities that prompted, enabled, or compelled her or his travel in the first place.The challenge is that we know nothing about the power dynamics of ancient Israelite/Jewish travel accounts. They are expected to reveal striking intersectional concerns, highlighting the complexity of human phenomena such as mobility. While multiple categories of difference characterize the travelling agents, mobility also affects and shapes these categories, e.g., by leading the agent to negotiate, refine, or recreate aspects of her or his identity. T
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'full harvEst of solar radiatioN using a quantum-dot-in-perovskite absorber and LIGHT managemENt structures' in the context of a Horizon 2020 call.

assistant: **Objectives**

Europe has set the energy transition to renewable sources as one of its priority policies to minimise the effects of climate change. Photovoltaic energy is called to play a major role in the world’s electricity production in the mid-term. The present market-dominant technology, crystalline silicon, has reached its practical efficiency record of 26% and the energy cost of this technology seems to be stagnating now. For these reasons, research on new ways of increasing the conversion efficiency of solar cells is still extensive. Among the proposed novel concepts for high-efficiency solar cells, the intermediate band solar cell (IBSC) has received great attention by the scientific community. In conventional single-gap solar cells, photons with energy lower than the bandgap of the absorber material are wasted. The IBSC concept allows harvesting below-bandgap photons without voltage loss, which increases the limiting efficiency from 33% to 50%. So far, IBSCs have been realized with epitaxially-grown quantum dot (QD) superlattices of III-V semiconductors. However, no pronounced efficiency enhancement has been yet reported, since this technological approach is unable to produce nanostructured materials with the properties required theoretically. In particular, epitaxial QDs exhibit low absorbance, leading to low photocurrent, and weak quantum confinement, which degrades the voltage of the cell. Recently, a new type of solution-processed semiconductor materials, quantum dots in a perovskite host (CQDs@Perovskite), has been demonstrated. The intrinsic opto-electronic properties of CQDs@Perovskite (high absorbance & strong quantum confinement) make them perfect candidates as absorber material in IBSCs. ENLIGHTEN will exploit CQDs@Perovskite materials combined with microstructure-
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Physico-chemical development of amphiphilic cyclodextrins' to be submitted under Fourth Framework.

assistant: **Abstract**

Cyclodextrins are cyclic oligosaccharides consisting of ct(1,4)-linked D-glucopyranosyl units. These macrocycles possess a hydrophobic cavity which can encapsulate molecules such as drugs, and can be chemically modified with relative ease. We propose to develop a range of novel water-soluble amphiphilic and dendrimeric cyclodextrins, which can potentially form different types of molecular assemblies, such as monolayers, nanospheres, polar heterodimers, micelles and liposomes. The most interesting possibility raised by these self-assembling host molecules is the formation of host-guest complexes within the supramolecular assemblies, applied to drug-delivery.These properties will be assessed by physico-chemical methods. Liquid crystalline properties will be investigated by DSC and X-ray diffraction. Micellisation (effects of structure, solvent) will be measured by light scattering and fluorescent probes. Liposome formation will be sought using electron microscopy and atomic force microscopy. Polar heterodimer formation between charged cyclodextrins will be measured by potentiometric titrations. The supramolecular assemblies confirmed above will be applied to inclusion of guests: inclusion of phosphonucleotides by cationic compounds will be studied by potentiometry; inclusion of fluorescent probes by micellar and liposomal systems will be followed by fluorescence spectroscopy; inclusion of peptide drugs such as Somatuline (Biomeasure Inc.) will be evaluated by NMR and UV spectroscopies. Training content (objective, benefit and expected impact) The Dublin Project will enable me to extend my experience of metal complexation to the complementary area of organic guest molecules complexes. It will widen my knowledge of physico-chemical methods and give me an interdisciplinary e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'An RNA-based mechanism for the nutritional control of bacterial DNA replication initiation' to be submitted under Horizon 2020.

assistant: **Abstract**

DNA replication is a fundamental biological process enabling the transmission of genetic information to progeny. In bacteria, its initiation involves a set of genes whose regulation is critical to ensure genome stability, both under optimal conditions and in response to environmental cues, including changes in nutrient availability. The highly conserved bacterial initiator protein DnaA has been proposed as a primary target for the nutritional control of DNA replication. Nevertheless, surprisingly little is known about the molecular mechanisms modulating its activity in response to nutrient limitation. Previous work showed that the synthesis and degradation of DnaA are both subject to control mechanisms that respond to environmental changes in the model organism Caulobacter crescentus. The 5’-UTR of dnaA mRNA was discovered to be required for the downregulation of the protein and the block of DNA replication initiation in response to nutrient depletions by a so far unknown post-transcriptional mechanism. Based on my preliminary in silico analysis I hypothesize that the 5’-UTR of dnaA can assume distinct conformations with different ribosome binding site accessibilities. Switching between these conformations is likely triggered by a trans-acting factor, either a small RNA, an RNA-binding protein or a metabolite, that is produced in response to nutrient availability. The present project proposal aims to elucidate the precise molecular mechanism underlying the post-transcriptional control of dnaA and to determine its consequences on DNA replication and cellular survival by combining classical biochemistry and genetics with cutting-edge molecular biology techniques. I expect that this work will contribute to the development of new strategies for bacterial growth control in i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Enzymatic Piezoelectric Composites To Regenerate Redox-Cofactors Driven By Mechanical Sources.' under Horizon Europe.

assistant: **Concept**

The cost-efficient production of sustainably derived biochemicals and biofuels is a critical goal of modern biotechnology. Redox-biosynthetic pathways are fundamental in chemical manufacturing for establishing a bio-based economy. The sustainable regeneration and recycling of redox cofactors is a pre-requisite for the viable industrial exploitation of many described redox-biosynthetic pathways. These boundaries hamper the employment of cofactor-dependent biotransformations at large-scale production processes. To overcome these limitations, the main objective of this project, PIEZOZYMES, pushes the forefront of technology, pursuing novel biotechnological tools aimed at the efficient regeneration of redox cofactors powered by mechanical sources. Such progress will bring several advantages over the current cofactor-regeneration systems, where the traditionally employed biochemical, electrochemical and photonic sources will be replaced by mechanical ones. The resulting technology of this project will have valuable social impact, paving new pathways for the cost-efficient exploitation of cofactor-dependent enzymes as economically suitable biocatalysts in a plethora of industrial catalytic biotransformations.


**Keywords:** Piezoelectric materials, enzyme immobilization, biocatalysis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'BLUE-Enterprise and Trade Statistics'.

assistant: **Innovation**

BLUE-ETS is a project on official business statistics and, specifically, on one of EU NSIs key challenges; that is, providing high quality and robust statistical information, for better policy and socio-economic research, and to support the renewed Lisbon Strategy, while: (1) reducing the response burden; (2) simplifying and setting priorities; (3) cutting costs on enterprises, that stem from red-tape, over-regulation and duplications; (4) modernizing and re-engineering the methods for the production of statistics; (5) making data collection less burdensome and providing more information . Along with the principles of subsidiarity and proportionality, BLUE-ETS key aim is to support and contribute to the success of the EU Commission Communications MEETS Decision including Better Regulation for Growth and Jobs in the European Union; Action Programme for Reducing Administrative Burdens in the European Union; and the Reduction of the response burden, simplification and priority setting in the field of Community statistics. Accordingly, BLUE-ETS is expected to contribute to the success of the EU MEETS Decision. Accordingly, the project is tailored on MEETS objectives, especially to “better and more-cost-effective statistics”, by (1) Distilling and spreading “EU-wide” frontier knowledge, stemming from different EU NSIs’ lessons from experience, on how to address common issues, which would allow to share problems, which are akin and involve applying knowledge in both collecting, producing and making available business statistics to governments and the public at large; (2) Learning from each other as to how “chart best” a common strategy and a road to cost-effectively and successfully address the MEETS challenges, without repeating mistakes; (3) Converging towards a coherent, c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'CPC collector for high temperatures'.

assistant: **Innovation**

Solar production of process heat in the temperature range of up to 150 C holds a very high potential to substitute high amounts of fossil energy. Many projects in solar building climatisation or solar water desalination are currently under evaluation. In these projects, the up to now only available solar collectors suitable for the desired high temperatures are vacuum tube collectors. However, there is a range of possibilities to improve the efficiency of flat plate collectors, avoiding the expensive vacuum technology: - concentration of the radiation using CPC mirrors - convection barriers - highly selective coatings - inert gas filling - low pressure filling First approximations show that a combination of these technics yields efficiencies for non-vacuum solar collectors higher than 50 % for temperatures up to 150 C. In the proposed project, the effects of these improvements will be evaluated. The aim is to develop a high temperature solar collector that allows lower production costs than evacuated solar collectors. Solar production of process heat in the temperature range of up to 150 C holds a very high potential to substitute high amounts of fossil energy. Many projects in solar building climatisation or solar water desalination are currently under evaluation. In these projects, the up to now only available solar collectors suitable for the desired high temperatures are vacuum tube collectors. However, there is a range of possibilities to improve the efficiency of flat plate collectors, avoiding the expensive vacuum technology: - concentration of the radiation using CPC mirrors - convection barriers - highly selective coatings - inert gas filling - low pressure filling First approximations show that a combination of these technics yields efficiencies for non-vacuum