RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'New deep-tech technology to help industrial, maritime, Oil & Gas companies comply with Agenda 2050 by reducing 99% of PM, VOC, and GHG emissions combined with x6-8 times lower expenses.'.

assistant: **Innovation**

Solumar is the brand name of a startup developing new deep-tech industrial solutions for air and gas purification and emissions-cutting with a strong and experienced team of Aviation, Software, and Maritime engineers, and young Key Account and Business development experts. We are an impact-driven team on a mission to help Industrial business owners, Construction companies, Maritime (ship owners and port operators), and Oil & Gas companies reduce pollutants and emissions by 98-99% in an efficient and sustainable way, without compromising their business needs.  Our journey started working with the R&D departments of AIRBUS Biz Lab and Liebherr Aerospace, then proved the technology on a smaller scale in non-aviation sectors - today we are selling to metal, wood processing, and pharmaceutical manufacturers in Europe.  We plan to expand in the Maritime and Oil & Gas industries because of the huge Climate change impact and the multi-billion market opportunity - in maritime only, the market size reaches $300bn by selling equipment and up to $200m annual recurring revenue by selling byproducts (Carbon black), also providing shipowners and port operators with an opportunity to comply with the net zero Agenda 2050, and help stop Global Warming and the Climate change. Interest has already been demonstrated by Greek ship owners, local Bulgarian Maritime cluster, both KAUST deep-tech Accelerator and Aramco in Saudi Arabia, and Norwegian companies, and the first demo prototype designed for Maritime integration is supported by Innovation Norway RD Grants (project started in August 2022). The technology borrows know-how from Aviation and embodies a unique working principle, deep-tech modular approach, and a design allowing to collect of particles, also Black Carbon and ash, VOC, and Ga
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Neonatal estimation of brain damage risk and identification of Neuroprotectants' under Sixth Framework.

assistant: **Concept**

NEOBRAIN is a project that brings together SMEs, industry and academic groups devoted to the diagnosis, management, and neuroprotection in newborns with perinatal brain damage. The focus of the project is the prevention of hypoxic-ischemic and inflammation-associated brain damage mainly observed in preterm newborns.The objectives of the project are 1. to generate marker profiles of damage in multiple animal models and in human preterm infants using genomic/genetic, proteomic, and metabolomic approaches, as well as imaging and electrophysiologic modalities; 2. to develop neuroprotective strategies by identifying candidate molecules for intervention using such markers and molecules in animals; 3. to implement a clinical platform for an observational clinical epidemiologic study in human infants designed to contribute to objective #1 above and to transfer insights gained in objectives #1 and #2 from the animal to the human level;  4. to prepare for drug testing by using the project structure as a clinical platform for initial steps in clinical testing of interventions discovered.We further envision developing the clinical platform in a fashion so it can serve as the basis for a subsequent large scale pan-European perinatal neuroprotective research initiative (Euro-Neo-Net, EURAIBI) that will enable us in the future to conduct additional clinical studies building upon the knowledge gained in NEOBRAIN.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Implementation of superior treatment regimen and improved patient pathway for neurocysticercosis in Sub-Saharan Africa' in the context of a Horizon Europe call.

assistant: **Objectives**

Neurocysticercosis (NCC) is a fatal zoonotic disease following ingestion of eggs of the pork tapeworm, Taenia solium. The eggs develop to larval forms (cysticerci) in various tissues, including those of the central nervous system, leading to NCC, mainly characterized by epileptic seizures. NCC management guidelines have been published by the WHO, however, their uptake in national policies is very limited. In NeuroSolve, we will demonstrate and promote a methodological approach for conducting health research that leads to improved adoption into policy and clinical practise. We will validate the approach by investigating evaluation- and implementation of an antiparasitic combination treatment and a serological test. Two health innovations that can make a major positive contribution to NCC management. The proposed approach includes (1) strengthening of clinical and research capacity through training and mentoring of early career researchers, clinicians and frontline healthcare workers as well as upgrading infrastructure for surveillance and control, (2) demonstrating the improved pragmatic effectiveness of the combined treatment on quality of life (3) evaluating the potential impact of serological testing on the patient outcomes and the wider health system through a simulation study, (4) demonstrating the cost-effectiveness and cost-benefit of the proposed health technologies, (5) developing and validating an implementation strategy that addresses identified barriers for uptake using the robust implementation frameworks and 6) enhance research results uptake into national and international guidelines and health policy through engagement of relevant policy makers throughout the project period and beyond. If the intended impacts are reached, NeuroSolve will improve health ou
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Decision support tools and methods for management and measurement of intellectual assets across cooperative networks' in the context of a Fifth Framework call.

assistant: **Objectives**

SME's are the backbone of the European industry. However, they face an increasing global competition and a fast changing economic and technological environment. Hence they start to cluster their core competencies in virtual networks in order to gain a competitive edge. Whenever it comes to concrete talks to form a co-operative network a key issue is the value, which is brought in by a single partner and the corresponding share of (future-) profits. But innovative products or innovation potential as such, intellectual assets of the human resources from the company, services with a high dependence on experience, novel approaches, research etc. are hard to evaluate in terms of values that a company contributes to the network. Therefore overall objective of the project is the assessment of the intellectual assets, which are inherently given in networking organisations. SME's are the backbone of the European industry. However, they face an increasing global competition and a fast changing economic and technological environment. Hence they start to cluster their core competencies in virtual networks in order to gain a competitive edge. Whenever it comes to concrete talks to form a co-operative network a key issue is the value, which is brought in by a single partner and the corresponding share of (future-) profits. But innovative products or innovation potential as such, intellectual assets of the human resources from the company, services with a high dependence on experience, novel approaches, research etc. are hard to evaluate in terms of values that a company contributes to the network. Therefore overall objective of the project is the assessment of the intellectual assets, which are inherently given in networking organisations.OBJECTIVESThe overall objective of the projec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Integrated next-generation flow cytometry and sequencing to uncover the pathway of curability in multiple myeloma' (MYELOMANEXT).

assistant: **Innovation**

Multiple myeloma (MM) represents a unique model to investigate cancer stem cells (CSCs), circulating tumour cells (CTCs), and the mechanisms of malignant transformation and chemoresistance. Despite the substantial improvement in MM patients’ outcome, the vast majority of patients eventually relapse and the disease remains largely incurable. For those patients failing to achieve deep remissions, biologically targeted research on the ultra-chemoresistant minimal residual disease (MRD) clone may allow us to understand the cellular mechanisms driving chemoresistance, and design novel therapeutic to overcome; importantly, such effort should be equally performed on two additional key players: CSCs and CTCs. On the opposite side, it is unquestionable that a selected group of patients does experience long-term survival irrespectively of the depth of response achieved, but we fail to understand the mechanisms driving sustained disease control. Is it because of persistent residual benign clones? Is it because of immune surveillance? Here, we will integrate next-generation flow cytometry and sequencing to define i) the signature of CTCs and ultra-chemoresistant MRD cells, ii) the hierarchical place of putative CSCs, iii) the genomic landscape of benign vs. malignant clones; and iv) the role of immune surveillance to achieve functional cures. Hence, we will characterize for the first-time-ever the highly-professional subclones responsible for malignant transformation, disease dissemination, and dramatic relapses after optimal response to therapy. Noteworthy, the innovative approach of this scientific proposal strongly relies on the use and expertise of highly-sensitive next-generation flow cytometry, coupled with optimized DNA- and RNA-sequencing for low-cell-numbers, and prospecti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Operation of Cavity Optomechanics in Fluids for Ultrasensitive Mass Detection' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

In cavity nanomechanics, researchers are racing towards the mechanical quantum ground states, however, it remains unclear how these interesting system could be usable in real applications. This project proposes that the cavity nanomechanics could find important use  in a broad range of applications in chemical and biological detection. The use of cavity nanomechanics as sensitive mass detection could potentially replace mass spectrometers in portable detection systems. These devices are light based force devices. They use recirculating  light to enhance the interaction of light and mechanical structure achieving an improvement of orders of magnitude in the intrinsic  sensitivity compared with the commonly used free-space interferometer.   The high displacement sensitivity translates to high mass sensistivity if the devices are employed in a sensing environment. The nanomechanical component of the cavity optomechanics provide extremely high mass sensitivity in mass sensing due to their excellent combination of small mass, high frequency and high mechanical quality factor. Zeptogram mass sensing has been achieved at low  temperature and in vacuum, however, the mass sensitivity in ambient air is much lower due to air damping.  In this project, the active oscillation resulting from regenerative cavity back-action brings about a new concept for ultrasensitive  mass detection. In contrast to passive resonators, these active oscillators do not require external ac stimulation and can be self-sustained.  With the proposed resonator (2GHz), the theoretical mass sensitivity in vacuum is predicted to be 10-24g, close to the mass of a H atom. Under ambient conditions, the practical sensitivity will be compromised by air damping of the mechanical oscillator, the readout noise of  the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Innovative Network for Next Generation Training and Sequencing of Virome' to be submitted under Horizon 2020.

assistant: **Abstract**

INEXTVIR is an innovative training and research programme that aims at providing to the next generation of young researchers unparalleled professional experiences and core competencies to resolve significant challenges across multiple disciplines in the academic, industrial and regulatory sectors. INEXTVIR proposes the use of cutting-edge Next Generation Sequencing (NGS) technologies for studying at an unprecedented depth the virome of selected agricultural crops and ecosystems across Europe and evaluating the impact and benefits it provides at the agricultural, socio-economic and policy levels. This is a timely and exciting research field suited to and benefiting from a trans-disciplinary pan European network approach. The work will cover virus discovery, characterization and the identification of ecological factors determining the structure and dynamics of virus populations in agricultural and wild ecosystems. This is critical to understand the epidemiology of disease and will enable informed risk assessment and decision making by the scientific and regulatory communities. In addition, the different stakeholders’ risk/benefit perceptions will be assessed enabling the development of effective communication strategies. Finally, the bioinformatics work (including data classification and presentation) and NGS method development and validation will facilitate the transfer, adoption and exploitation of innovations in plant protection and routine diagnostic settings. In summary, INEXTVIR will enable the fellows to understand the wider context behind their research, which will maximize the impact of their work in contrast to conventional PhDs. Furthermore, they will receive training in transferable skills including project, people, quality and IP management, communication and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'SYMBIOSIS and DEFENCE IN THE INTERACTION OF PLANTS with MICROORGANI SMS'.

assistant: **Innovation**

Symbiosis and defence are two basic principles in the interaction of microorganisms with plants. The major objective of the network is to pool more than 60 young scientists from other European countries, most of them from EU member countries (see Appendis I). Several of the participating the expertise of nine laboratories in the fields of microbiology, plant network laboratories have joint publications. The postdocs of the network sciences, cell biology, molecular genetics and molecular phytopathology to study these two phenomena together at a molecular level. So far these two will have the chance to be trained in modern methods as molecular ecology (Finland, Ireland, Spain), immunological methods (UK), cell biological phenomena have been studied mainly in different departments and disciplines: symbiosis in biology department, defence reactions in methods (France, Germany, UK) and molecular genetics (The Netherlands, phytopathology departments. Greece). The network includes laboratories with main-interests in basic research as well as those with a strong emphasis on application. The model organisms studied are Rhizobium/ Bradyrhizobium, arbuscular mycorrhiza fungi and Pseudomonasfluorescens (as antagonist) in the interaction with legumes and other plant families.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Mechanistic Integration of vascular aND endocrine pathways for Subtyping Hypertension: an Innovative network approach for Future generation research Training'.

assistant: **Concept**

Hypertension is the key determinant of cardiovascular disease and the No.1 ‘silent killer’ of humans worldwide. Despite progress in understanding the causes of hypertension and improvements in clinical management, >85 million people in Europe suffer from cardiovascular disease, costing the EU €210 billion/year. Currently, there is a crucial gap in understanding the dynamic interactions between vascular and endocrine pathways in hypertension. Such knowledge would facilitate redefinition of hypertension subtypes to improve current prevention and treatment. MINDSHIFT will offer a top-level interdisciplinary research programme to bridge this gap, using an integrative framework approach fed by new data and insights from cutting-edge experimental and clinical studies. To enable this advance, MINDSHIFT will implement and run an innovative EJD-programme, combining first-class scientific research with in-depth professional and transferable competence-skills trainings. ESRs will develop the integrative and entrepreneurial capacities that hypertension research demands by nature. Above and beyond, the programme will challenge the ESRs to build their capacity for self-directed learning, career development and personal-professional leadership. The highly capable academic and non-academic partners in MINDSHIFT have co-designed an extraordinary high-quality programme of research projects and network-wide training elements, to achieve the required and sustainable impacts on the ESR careers, scientific results and ITN-wide learning and innovation. Based on the excellent synergies and shared commitments, the MINDSHIFT consortium seeks to establish a European School for Hypertension Research, to propel future health science and industry towards more effective prevention of and cure for thi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'From Health Research to Market – Advanced Services and Training Actions for the IPR Management and Business Exploitation of the EU-funded Research Results in Health/life sciences' to be submitted under Seventh Framework.

assistant: **Abstract**

Health-2-Market is an ambitious project aiming to boost the economic exploitation of EU-funded research results in the area of Health/life science. The project focuses on the actual Health/life science knowledge generators, namely the researchers,  involved in EU-funded research in Health with a view to cultivate to them an enhanced innovation and entrepreneurial culture. More specifically, Health-2-Market will aim at providing Health researchers with the necessary knowledge and skills for more viable IPR management as well as market exploitation of their results through the setting up of new business ventures in health/life science sectors or in a more broad sense through their more active involvement in interdisciplinary cooperation actions. More specifically, Health-2-Market is expected to offer a set of high-level services including advanced training courses,ad-hoc and on demand counselling as well as specific coaching (both through web as well as face-2-face) addressing innovation issues such as: IPR and asset management, formulation of business and exploitation plans, preparation for the launch of start-ups in health/life science as well as on demand knowledge transfers. Health-2-Market services will be offered by a pool of experienced internal specialists as well as external ones coming from leading academic and industrial organisations. The provided services will be escalating to address the needs of the potential target groups: Web (e-learning) courses for broader audience, two-day seminars on specific topics, advanced training courses (intensive training academies), hands-on support and ad-hoc counselling services either through face-to-face meetings, or distance ones, etc.  The project will cover all EU MS and AC through its broad partnership as well as throu