RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'New generation single-shot LiDARs with the PicoAD monolithic detector'.

assistant: **Concept**

Light Detection and Ranging (LiDAR) is a remote sensing technology that measures object distances by analyzing the time-of-flight of photons. LiDARs emit short laser pulses, detect their reflections, and precisely measure travel time. Using a pixel matrix sensor, they can generate detailed 3D images, used for e.g. autonomous vehicles, industrial automation, robotics, and augmented reality.Despite being a rapidly growing emerging market, current LiDAR technology is still far from being fully developed. In particular, next-generation LiDAR sensors must achieve greater background light rejection to operate in complex conditions as well as reduced latency to enable real-time detection capabilities.This project will build upon the patented Picosecond Avalanche Detector (PicoAD), developed within the MONOLITH ERC_AdG project. It will design and validate a proof-of-concept PicoAD version specifically tailored for LiDAR applications. This version will enable fast analog signal filtering at the pixel level and precise time gating to detect only photons from the laser pulse. Thereby it will suppress background light noise far more effectively than current methods and improve reliability in adverse ambient conditions.Unlike conventional LiDAR sensors that rely on multi-shot measurements, our PicoAD will enable single-shot photon detection, dramatically enhancing acquisition speed. This will provide significant advantages for applications requiring real-time decision making such as collision avoidance in autonomous vehicles. Robust circuits will be designed to function across a wide temperature range from -40°C to 125°C.In addition, the high-speed electronics will incorporate multiple-return processing, enabling the detection of multiple reflections from a single laser pulse. This
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Mass Produced Optical Diagnostic Labcards Based on Micro and Nano SU8 Layers' under Sixth Framework.

assistant: **Concept**

The emergence of new pathogens or variations has created recently severe threats to human health (E.coli O157:H7, SARS, the avian-flu disease). The gravity of the problem resides on the fact that their impact and spreading is growing dramatically due to the ongoing increase in worldwide human mobility in combination with trade in livestock, and food products. However, detecting the source of infection through conventional analytical methods requires complicated and time-consuming protocols. The project aims the development of a quick and low-cost diagnostic device (Lab on a Card) that develops and integrates technology advances in optoelectronics, microfluidic and microbiology, capable to detect, in-situ, DNA pathogens in 15 minutes.The device consists of a hand held base unit and a cartridge or labcard that will carry out a Real Time Polymerase Chain Reaction automatically, from sample preparation to an optical detection. The labcard, made of a photo resist called SU-8, on a plastic film, contains all the disposable components, whereas the base unit includes all the standard electronics and optics. The range of applications is limitless (infectious diseases, flu, tuberculosis, hepatitis, AIDS, cancer, etc) and it will be validated on Salmonellosis and Campylobacter detection.The scenario where this diagnostic device is used covers hospitals, food factories and private homes. Its impact will be enormous, reducing the incidence of infectious illness, and providing EU governments with a certificated tool to quickly monitor and survey the sources of pathogen contamination. An especial emphasis will be applied to develop and use micro fabrication processes that are compatible with mass production and low cost of the devices offering a protected and disruptive technology to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Polarons in doped dielectrics and the metal-insulator transition' (1994-1998).

assistant: **Innovation**

Polarons have been observed in many insulating oxides, and also in the insulating phase of High Temperature Superconductors materials (HTSC). The latter are highly polarizable and can be strongly doped, leading to the Metal-Insulator Transition (MIT). The formation of polarons and their mutual interactions cannot be forgotten as an essential feature of the MIT. Due to strong coupling, polarons still form at rather high doping levels in the insulating phase and, due to their high effective mass, may cristallize in a polaron Wigner lattice. The aim of the project is to investigate different theoretical scenarii for the MIT, depending on the electron effective mass, polarizability and phonon frequencies. On may obtain a gas of polarons, or a quasi-free carrier gas, possibly coexisting with localized polarons. This is aimed to clarifiy the nature of the metallic phase and the relevance of polaron formation in the superconductivity mechanism.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Advanced control of renewable energy generation systems based on fuel cells\wind power', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The European Union is conscious about the fundamental problems arisen from the current energy system, based mainly on hydrocarbons and has a firm commitment to encourage renewable energy technologies research. Among experts in energy there is a growing trend to promote Decentralised Electrical Generation Systems (DEGS) with modular efficient non polluting generation plants. DEGS that incorporate hydrogen as an energetic vector are of particular interest. Hydrogen can be easily produced, stored and efficiently converted into electricity by means of fuel cells, adding great flexibility to DEGS. However, fuel cells based DEGS exhibit complex non linear behaviour, have inaccessible variables and withstand severe disturbances, so special controllers are required. A wide range of linear controllers have been already proposed, but the validity of the results cannot be extrapolated. The development of advanced control systems for fuel cell based DEGS that incorporate renewable energy sources is then not merely a challenging area of research, but is also a field of great interest for environmental, social, economic and strategic reasons.The key aim of this project is the development of advanced controllers capable to improve the efficiency of fuel cells\wind power based DEGS. They will be implemented and tested in the ACES labs in Barcelona. The results of this implementation will be used to assess the theoretical developments and will also provide a technology demonstrator to aid technology transfer to industry. The main objectives of the proposed project are threefold:- Scientific. Advanced controllers will be developed to improve the efficiency of DEGS- Knowledge transfer. The Visiting Professor will instruct and train the host group in new control techniques, particularly hi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'TECHNEAU: technology enabled universal access to safe water' (TECHNEAU).

assistant: **Innovation**

Many of the numerous small supply systems in rural areas in Europe and developing countries do not comply with regulations. Large centralised supply systems in industrialized regions are struggling to meet the challenge of a reliable, uninterrupted supply of water with a high level of compliance with standards and of minimal risk to human health, including the risk from deliberate contamination of water, whilst being accepted and trusted by consumers.It is the vision of TECHNEAU that, in order to cope with present and future challenges, water supply systems should consider a transformation from mono-scale to flexible multi-scale systems i.e. interlinked centralised and decentralised satellite treatment, monitoring and control systems. TECHNEAU will develop and demonstrate adaptive supply system options and new and improved supply and monitoring technologies and management practices. Treatment strategies will be based on robust multi-barrier schemes and control methodologies, providing safety against a broad spectrum of chemical and microbiological contaminants and avoiding organoleptic problems at the tap. Monitoring technologies will provide on-line and at the site information on water quality including parameters that relate to malicious contamination. Practices for risk assessment/risk management, operation and maintenance, and models for consumer acceptance will constitute the framework for these technologies.These technologies and management practices will enable end-users to make informed choices, appropriate to their own circumstances and constraints, for cost-effective and sustainable source-to-tap solutions for the provision of safe high quality drinking water that has the trust of the consumer. This step-change will be achieved by a critical mass of researcher
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Photopolymer based customized additive manufacturing technologies' under Seventh Framework.

assistant: **Concept**

Lithography based additive manufacturing technologies (AMT) are capable of fabricating parts with excellent surface quality, good feature resolution and precision. With recent developments in the field of ultra-short-pulse lasers and light engines based on light emitting diodes, robust and economical light sources have become available. This project aims at developing integrated lithography-based additive manufacturing systems which will, for the first time, facilitate the processing of photopolymer-based materials for the factory of the future. The focus of the project is to unite industrial know-how in the field of supply chain management, software development, photopolymers and ceramics, high-performance light-sources, system integration and end-users in order to provide a fully integrated process chain at the end of the project. The consortium will rely on two core-technologies: (1) Digital light processing (DLP) based processes will be used to process ceramic-filled photopolymers, leading to fully dense ceramic parts at the end of the process chain. (2) Two photon polymerization (2PP) will be used to fabricate high-resolution structures with features in the range of 100-200nm. Both processes will be tuned to reduce system cost, and significantly increase throughput and reliability at the same time. Goal is to deliver 'first-time-right' strategies for the involved end-users. This necessitates the development of supply chains with integrated quality sensors. Targeted applications include thread guides for textile machinery, ceramic moulds for the fabrication of high-performance turbine blades and microstructures for computer tomography equipment.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Study of g1 cyclin degradation in scerevisiae', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Objectives and content of the project Cell cycle progression in eukaryotes is controlled by the p34cdc2/CDC28 protein kinase and its short-lived, phase-specific regulatory subunits called cyclins. In budding yeast, Start is the major checkpoint that coordinates progress of the cell cycle engine with cell growth, nutrient availability and signals from other cells. Three redundant, unstable Gl cyclins (Clnl, Cln2 and Cln3), through their assosiation with Cdc28, allow budding yeast cells to pass Start. The aim of this project is to understand the molecular mechanisms involved in Gl cyclin degradation and their relationship to the cell cycle regulatory network using both genetic and biochemical approaches. We plan to: 1. screen for suppressors of the grrl mutant, in which Clnl is stabilized 2. test Gl cyclin stabilization in different ubc mutants 3. reconstitute active Cdc281Cln complexes for use in an in vitro degradation system Training content (objective, benefit and expected impact) The reconstitution of active Cdc28-Cln complexes will be extremely important in biochemically dissecting the Gl cyclin degradation pathway. In fact, this approach will allow us to test the direct involvement of genes, isolated by standard genetic techniques, in Gl cyclin proteolysis. The results obtained with this work can yield substancial information on the mechanism and biological role of Gl cyclin degradation in relation to the cell division cycle. Links with industry/ industrial relevance This is an industrially relevant proposal since the understanding of protein degradation (and in particular of G I cyclin degradation) might be crucial for the isolation of anti-tumor drugs. In fact it has been shown that cyclins (such as cyclin D I, a human G l cyclin) are directly involved in some hu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Electric Two-Wheelers on Urban Roads' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

Mission Statement: To demonstrate, evaluate and promote the advantages of electric two-wheelers as a substantial contribution to sustainable mobility in urban areas. Based on:- Introducing and testing of over 1.000 electric two-wheelers in 8 European cities, in order to obtain a modal shift towards two-wheelers, by promoting these new mobility means;- Promoting and dissemination of the results, as a contribution in preparing large-scale introduction of these vehicles in the market;- Use of electric bicycles is aimed at increasing driven range of bicycle use and range of user groups;- Use of electric scooters is aimed at replacing scooters and cars with internal combustion engines;- To develop, install and test devices facilitating the use of these means;- To investigate new technologies for alternative two-wheelers and the physiological/bio-ùechanical aspects of power assisted bicycles in relation to lowering the threshold for a relevant part of the citizens (including ageing).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Validation of Innovative Lipopeptide Antibiotics' (VOILA), addressing dissemination and exploitation.

assistant: **Impact**

Antibiotic resistance presents a growing threat to global health. The emergence of the superbugs is alarming: at current rates of increase, and without new intervention strategies, antibiotic resistance could cause a staggering 10 million deaths/year worldwide by 2050. Therefore, new approaches need to be developed to combat antibiotic resistance, particularly for the WHO’s priority pathogens which include the so-called ESKAPE family of dangerous drug-resistant bacteria.Recently, we developed a novel technology platform comprising a set of methodologies to semisynthetically modify the natural antibiotic nisin. In doing so we generated novel lipopeptide antibiotics with a much higher in vivo stability than the parent compound. These semisynthetic antibiotics possess a lipid II-mediated mode of action similar to nisin, which sets them apart from any current clinically-used antibiotic. During my ERC CoG, we have significantly improved these compounds, i.e. increased their antimicrobial activity and eliminated undesired haemolytic effects. Importantly, preliminary data shows that these antibiotics have a lower propensity to lose their potency due to antibiotic resistance development. I propose that these innovative lipopeptide antibiotics present a significant step forward in addressing the alarming threat of antibiotic resistance. However, to establish their commercial viability and broad applicability, the efficacy and preliminary safety of the new compounds need to be addressed. This can best be achieved via a PK/PD proof of concept study in appropriate animal models along with with a detailed evaluation of the business opportunity.The main objective of VOILA is therefore to establish both the technical feasibility and commercial viability of an entirely new class of lip
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Audiovisual Speech Segmentation and Oscillations' (AVISSO) targeting Horizon 2020.

assistant: **Abstract**

Daily social tasks (e.g. meetings, shopping) rely on human communication with speech. Auditory only studies established that continuous speech segmentation relies on the temporal integration of rhythmic acoustic features occurring at delta-theta rates in the signal, via a possible mechanism of entrainment coupled with beta activity. In terms of neural correlates, the timing network (including the basal ganglia, supplementary motor area and cerebellum) may actively contribute to the temporal integration of auditory signal during continuous speech segmentation. However, speech is often multimodal and listeners need to integrate speaker’s body movements aligned to rhythmic acoustic features. Consequently, AV speech may generate different rhythmic patterns than auditory only speech. How the brain translates naturally concomitant AV rhythms to facilitate speech segmentation clearly remains to be addressed. The goal of this project is to investigate the oscillatory patterns and neural correlates of AV rhythms resulting from the temporal integration of body movements and salient acoustic features in speech. In a first EEG experiment, I will compare the modulations of delta-theta entrainment and coupling with beta activity, depending on the relationship between visual and auditory information (congruent, incongruent and auditory only). Secondly, in an fMRI version of the experiment, I will explore the contribution of the timing network during AV speech segmentation, and its different patterns of activations across speech conditions. Finally, to test whether the brain areas revealed by fMRI have a necessary role for the successful AV speech segmentation, I will run the same fMRI experiment with Parkinson’s disease patients with dysfunctional basal ganglia. Looking at the timing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Improvement of eels microanalysis in materials science', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Electron Energy Loss Spectrometry (EELS) is a powerful method for micro-analysis in the Transmission Electron Microscope (TEM). It excels with a high spatial resolution, higher sensitivity than X-ray techniques and provides information on binding state and crystalline environment of the sample. Previous attempts to solve one great remaining problem, the intermingling of elastic and inelastic electron scattering, are theoretically and computationally highly demanding and did not lead to generally applicable results. After one year's research I think having found a practicable way to include dynamical diffraction effects in the modelling of inner-shell excitations. I intend to create a software package for simulation of doubly differential scattering cross sections for various crystals and compare these simulations to experiments. During my work I shall profit from my superviser's B. Jouffrey expertise, the experience and infrastructure accumulated at Ecole Centrale Paris (ECP) and other research laboratories situated in the Ile de France.