RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Development and Manufacturing of an All-Oxide Inter Turbine Duct for Aeroengines' under Horizon 2020.

assistant: **Concept**

The objective of the proposal is the development of an all-oxide Ceramic Matrix Composites (CMC) inter turbine duct for testing of the component in a demonstrator engine. The development steps include:- Designing the parts including the attachment to the metallic support structure- Defining design rules how to work with oxide CMCs for engine parts- Simulation of the parts behavior under engine loads- Assessment of the lifetime and reliability of the material in operation to translate the specimen behavior onto the component level- Optimizing the performance of the parts w.r.t. manufacturing parameters e.g. fiber orientation- Characterizing the material properties needed for the design process on specimen level. This includes the material development for example to improve the matrix system for prepreg technology- Manufacturing of the demonstrator parts- Develop a concept for fining qualification steps- Develop a concept for non-destructive testing- Validating simulation results with engine data resulting from engine testsFor manufacturing oxide CMCs specimen and parts the following manufacturing techniques are included in the proposed project:- Winding- Prepreg technology (as automated as possible)- BraidingThe path to final manufacture and validation will be documented and coordinated in close collaboration with the consortium partners and the topic manager.This proposal answers the CfP in “Work Package 4 – Advanced Geared Engine Configuration (HPC-LPT)” of the Engine Integrated Technology Demonstrators in Clean Sky 2. It utilizes the low specific weight of oxide CMCs to save weight and its inherent oxidation and temperature resistant nature to save cooling air. It therefore, contributes to the key objectives of the work package: improvement of efficiencies and innovat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'ATMOSPHERIC IMPACT CALCULATOR ENGINE FOR AIR TRAFFIC MANAGEMENT (ICE4ATM)'.

assistant: **Objectives**

Atmospheric dispersion of hazardous substances (mainly volcanic ash, but also mineral dust or SO2) influences manyeconomic markets, and poses a variety of problems to the aviation industry. For example, the presence of airborne volcanicash at low and jet-cruise atmospheric levels compromises the safety of aircraft operations and forces delays, cancelationsand/or re-routing of aircraft to prevent encounters with volcanic ash clouds. Volcanic eruptions are recurrent events withmore that 500 active volcanoes and an average of 80 eruptions a day affecting the aviation industry. Despite the existingdemand for solutions capable to evaluate and manage these natural hazards, and to provide credible operational expertiseto improve risk management across multiple industries, to date, no commercial product is available in the market to solvethese problems.MITIGA Solutions (www.mitigasolutions.com) is a firm specialized in evaluating and mitigating the impacts of volcaniceruptions for the aviation industry. MITIGA develops and commercializes, amongst others, products to quantify volcanic risksin order to improve air traffic management, insurability and urban resilience. In particular, MITIGA specializes in thedevelopment of the first operational system (ICE4ATM: Solutions on Real Time for Air Traffic Management) to forecast andmitigate the impact of volcanic ash across different aviation stakeholders in real-time. MITIGA’s core members have a wideexperience and expertise in developing and implementing local and regional modeling systems for quantifying impacts ofvolcanic hazards and provide support to volcanic risk reduction and disaster management. MITIGA Solutions is a spin-off ofthe Barcelona Supercomputing Center (www.bsc.es), a world renamed institution with over two decades o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Magnesium and fetal metabolic programming: an approach to preventing a life-cycle of metabolic diseases' to be submitted under Horizon Europe.

assistant: **Abstract**

Obesity prevalence is increasing as well as the related metabolic alterations. Obesity and T2D increase the risk of pregnancy complication and affect offspring health through developmental programming effects. Obese patients with T2D frequently present Mg2+ deficiency. During pregnancy, Mg2+ needs increases, and its insufficiency may affect the mother and fetus, interfering with pregnancy development and offspring growth. Although it is known the relevance of Mg2+, its role in pregnancy is often overlooked and the underlying mechanisms that causes disturbances on Mg2+ homeostasis are unelucidated. Mg2+ homeostasis is carefully regulated. Among the channels are the cyclin M 1-4 (CNNM1-4), highly conserved molecules. Although it has been suggested that Mg2+ transport and homeostasis plays a key role in development, its regulation during development and in maternal-fetal communication is not fully understood. Fetal growth is closely related to the placenta capacity to transport nutrients and ions. At birth, the fetus makes a transition from using placental nutrient supply to utilize the liver. Thus, changes in maternal liver metabolism related to Mg2+ levels and signalling could affect the maternal metabolic state and negatively impact the developing fetus. This project aims to assess the role of Mg2+ homeostasis and transport through the CNNMs in programming effects in the context of maternal T2D and obesity. We will focus on the role of Mg2+ on fetal programming effects in a context of altered maternal metabolism and to evaluate the impact on offspring liver. In addition, we will evaluate the potential dietary intervention with Mg2+ supplementation for ameliorating offspring-derived effects. We hypothesize that maternal obesity leads to an altered environment that involv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Geometric study of Wasserstein spaces and free probability'.

assistant: **Innovation**

The proposed research is divided into two main work packages. The first one is the study of spaces of measures equipped with the optimal transport distance (Wasserstein distance) with a special emphasis on the structure of isometries (surjective distance-preserving maps) and isometric embeddings (not necessarily surjective transformations that preserve the distance) of these spaces. The second work package is devoted to the investigation of measures from the viewpoint of free probability theory. This work package covers three subtopics: the qualitative behaviour of the free convolution, new random matrix ensembles arising from tensor networks, and the study of free Wasserstein spaces.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Large-scale renewable energy grid integration with redox energy storage ('REI-STORE')' (REI-STORE) under Fifth Framework.

assistant: **Objectives**

This combined RTD and Demonstration project will aid the integration of a 140 MW offshore wind farm through the provision of regulating power. The project provides a technology solution to the barriers limiting the value and future prospects of variable renewable generation. An innovative electromechanical energy storage technology, with a performance and cost structure better than that of pumped hydro, will be developed. Research will lead to a variety of innovations that will allow a 200MWh plant to be built for 90 EURO/kWh with a substantially improved efficiency and footprint compared to the pilot plant. The commercial and technical drivers for energy storage, as well as the expected dynamic performance, will be fully examined to determine the optimum configuration.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Computation Systems Based on Hybrid Spin-wave–CMOS Integrated Architectures' (SPIDER), addressing dissemination and exploitation.

assistant: **Impact**

In the future, the miniaturisation of electronic devices– epitomised by Moore’s law – will be progressively limited by increasing power densities and the associated chip heating. Moreover, autonomous microelectronic applications, for example for the Internet of Things, demand high performance at ultralow power. Therefore, much research has recently focused on disruptive computing technologies that limit power consumption and optimise performance per circuit area. Spin wave computing is a disruptive spintronic technology that uses the interference of spin waves for computation and has considerable potential for power and area reduction per computing throughput. Despite much recent progress in the realisation of spin wave logic gates, no concept for a complete computing system exists today that is based only on spin waves. Thus, to advance from devices to systems, spin wave devices need to be complemented by CMOS in a hybrid spin wave–CMOS system. Using an interdisciplinary approach joining partners with expertise in materials science, physics, device manufacturing, electrical engineering, circuit design, and packaging, SPIDER targets the demonstration of a complete operational hybrid spin wave–CMOS computing system. To date, complex spin wave circuits are yet to be realised. SPIDER targets to fill this gap by developing spin wave logic circuits based on majority gates. To embed these circuits into a CMOS environment, SPIDER will design mixed signal CMOS chips that can drive spin wave circuits and read out computation results. The spin wave and CMOS chips will then be combined on an interposer to obtain the final hybrid system. This work will pave the way towards viable spin wave chips and provide a first benchmark of spin wave computing at the system level. Based on the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Reactor neutronic investigations on lr-0 reactor' (RENION).

assistant: **Innovation**

Zero power reactor LR-0 available at Nuclear Research Institute Rez is an unique experimental tool which allows to model VVER and also PWR cores in 1:1 scale, to use lattices of hexagonal and square geometry, to measure the basic neutronic core parameters. It is eminently suitable for the verification of neutronic codes, measurements of pin-wise fission density distribution, experiments connected with compact fuel storage (VVER-440 and VVER-1000), investigations of burnable absorber influence on neutronflux distribution, gamma-fields.Examples of LR-0 capabilities:- Extension of experimental database and modelling capability with respect to control rod influence on power peaking. A special advantage (already available VVER cores) is expected for VVER-440 modified fuel designs with different absorber and fuel materials;- Experiments for the purposes of verification and validation of computer codes used for computations of cores with burnable absorber.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Smart Crystal Nucleation near Interface Dynamics in Active Pharmaceutical Ingredients', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

One of the most important challenges that drug development researchers face today is the low aqueous solubility of the active pharmaceutical ingredients (APIs). Most of the drug molecules under investigation exhibit poor water solubility and additional efforts are required to improve their solubility feature. Thus, the development of amorphous drugs is the most effective way how to improve the bioavailability of the APIs, and huge amount of effort is directed towards this smart approach. The aim of this project is to develop a reliable and universally applicable dynamic physio-chemical procedure for the description of the interconnection between the microscopic and macroscopic description of the triggered phase transformation – a task that would lay fundamental principles for the prediction of the macroscopic manifestation of the sub & near-Tg crystal growth in the class III amorphous drugs. This proposal is ‘SMART’ as this is first case of designing the unique green, dynamic and advanced molecular crystal nucleation near interface. In addition, the SMART project also aims to develop the combined experimental and mathematical procedural approach for fast, reliable, and accurate projections of the sub & near-Tg amorphous-to-crystalline dynamic transformation in amorphous APIs.


**Keywords:** Amorphous solid dispersions,  smart solid-state properties,  phase transformation,  amorphous drug molecules
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Demonstration of a High Definition Low Light Sensor (Starlight) for use in the Surveillance and Protection of Urban Soft Targets and Critical Infrastructures.' in the context of a Horizon 2020 call.

assistant: **Objectives**

The security market and owners of urban soft targets and critical infrastructure, require high definition surveillance systemsto monitor safety and security. Our innovative solution meets these needs by providing a value for money, light sensitivesensor that produces high definition images of non-illuminated areas at night and in low light conditions.Current technology suffers from poor light conversion and sensitivity therefore, to see at night and in low light conditions, thescene needs to be illuminated. Our proposal is to improve sensitivity by using sensors with organic compounds that aresensitive to background sky radiation (1.5 micron). We will also develop Application Specific Integrated Circuits to processthe sensor output. The novelty in our innovation is the integration of new technologies and the processing of data producedby a 1.5 micron organic sensor. This will deliver high resolution images at night and in low light conditions.Our solution will reduce the energy required to illuminate urban soft targets and critical infrastructure. Added benefits includea reduction in light pollution and that surveillance can be carried out in areas which have lighting restrictions. Thedevelopment of a proven, production ready system is the ultimate aim of the project. In Phase 1 we will carry out a feasibilitystudy to verify the technological, practical and economic viability of our proposal. Our feasibility study will consider the resultsof relevant European and International research.We plan to further develop our prototype and carry out a small-scale demonstration of our innovative solution. The results ofPhase1 will inform the direction of our future development activity in Phase 2. Our plan for full commercialisation of theproject will be to market the product init
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Human-centred collaboratIVE MultI-ageNt framework for accelerating software Development and maintenance' (HIVEMIND) under Horizon Europe.

assistant: **Objectives**

HIVEMIND is an ambitious project aiming to advance responsible and human-centric software engineering methods, tools and best practices leveraging AI and data technologies to accelerate the whole software development lifecycle. To this end, the project introduces an adaptive LLM-based multi-agent framework that enables collaboration between human actors and multiple AI agents tailored to mirror and provide specialised support for the various roles within a traditional software development team. Each of the agents will be clearly defined and specialised through multiple modalities of model customisation encompassing i) Fine-tuning with organisational data, ii) Prompt-engineering, iii) Retrieval Augmented Generation, and iv) Human-in-the-loop Machine Learning. These agents will be crucial for the development of mechanisms that support smart system specification, allowing to automatically derive complex requirements and facilitating agile modelling while considering inconsistencies and ambiguities, reducing the number of modifications needed in later stages of the software development lifecycle. Furthermore, HIVEMIND is positioned to support design-by-contract programming at all levels of integration by increasing the context awareness of AI agents that assist code development, analysis, verification and testing, allowing them to access relevant documentation during the development process. Moreover, HIVEMIND extends beyond the development phase, providing comprehensive support for the entire software lifecycle, covering software maintenance, including for multi-architecture systems. It represents a synergistic effort, merging the expertise of leading EU software engineering academics, AI researchers and industry representatives into a unified open-source framework targete
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Characterisation of PI3K isoform roles in pancreatic cancerogenesis' (2007-2013).

assistant: **Concept**

PI 3-kinases (PI3Ks) are key signal transduction enzymes which are generally considered to be excellent new targets for therapeutic interference. Mammals have multiple PI3K isoforms.During my UK post-doctoral training funded by EIF, I have created and characterized new mouse models targeting one isoform of PI3K, p110beta, which physiological role was unknown. Isoform-specificity of p110beta in cell signalling, and in physiology, in particular in angiogenesis, was investigated using these gene-targeted mice. These results led to a revisited classification of PI3Ks.PI3K signalling is altered (constitutively active) and correlated with a poor pronostic in pancreatic adenocarcinoma. Pancreatic adenocarcinoma is one of the most lethal cancers and no chemotherapeutic treatment is currently available for this type of cancer. In this proposal, I will study the isoform-specific role of the signalling enzymes PI3Ks using new unique mouse models created and characterised during my post-doc in which each isoform of PI3K is genetically inactivated. While PI3K inhibitors are already tested in clinical trials for cancer applications, the implication of the different isoforms of PI3K in cancer is still unclear and intensely debated. This project targets to increase the understanding of the complex relationship within the different isoforms of PI3K in cancer cell signalling in vivo, in order to better target and prevent secondary effects in this clinical context.This re-integration period in Toulouse, France, will allow me to be familiarized with mouse pancreatic models used by the Host Group. Having secured a permanent position as a junior scientist in the Host team, I aim to integrate myself in this new cancer research environment and to develop my independence inside this group by im