RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'A modular sensing and imaging toolkit for the early diagnosis of prostate cancer employing lab-on-the-chip methodologies'.

assistant: **Innovation**

This Proof-of-concept project will focus on the innovative exploitation of new diagnostic sensor prototypes which will tackle the early diagnosis of prostate cancer (PCa), one of the greatest concerns for ageing men worldwide. The development of fast and reliable methods for detecting PCa by electrochemical or optical biosensing will address the unmet need for an early diagnosis and for monitoring non-invasively the PCa evolution post-diagnosis. Current PCa screening methods detect the prostate-specific antigen (PSA) by enzyme-linked immunosorbent assays (ELISA), but struggle to achieve detection limits below 1 ng/ml. This level of sensitivity is insufficient for the detection of circulating cancerous cells before symptoms of the disease appear: low levels of cellular cancer biomarkers such as PSMA (Prostate-specific membrane antigen) are present in blood up to 5 years before diagnosis. More accurate sensors interfaced with an actuator in sensing devices using lab-on-the-chip and applicable in ‘real-time’ will be devised hereby. The innovative prototypes of Tools-To-Sense will incorporate the chemical sensors already available through the underlining ERC Consolidator Grant O2Sense, which are tailored to target PCa cells for molecular imaging applications. These will be able to estimate the concentration of circulating PCa cells as the complex analyte under interrogation. We will focus on target identification and validation, bioassay development and quality control for early detection of PCa using nanotechnology. Biosensors incorporating peptides-functionalised graphene substrates will be assembled since field-effect transistors can achieve high sensitivity for the detection of a panel of PCa biomarkers. New biosensors incorporating dedicated molecular species that prov
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Acoustic Black Holes for Silent SYstemS'.

assistant: **Concept**

The ABHSSYS project ambitions to disrupt noise reduction technologies while addressing the need for industrial decarbonization through a ground-breaking approach: Acoustic Black Holes (ABH). Unlike conventional noise reduction solutions, which often increase mass and carbon footprint, ABH offer significant noise reduction without adding weight. Across EU, 40% of the population is exposed to noise levels exceeding 55 dB(A), leading to health and social costs reaching 40 B€. Reducing noise pollution is therefore a central issue for the EU citizens well-being, and is associated with strong technological challenges in the field of vibroacoustics, particularly in the mechanical industry, one of the main source of noise pollution. ABH is a radically new technology and has strong scientific and industrial potentials, as it is intrinsically i) parsimonious and environmentally friendly: its use reduces the mass and volume of acoustic treatments by around 20%; ii) tunable: ABH enable considerable noise and vibration reduction with only minor or local modifications of the structuring, and are compatible with usual industrial processes; iii) multifunctional: ABH can be applied to many industrial fields without requiring new designs. Moreover, on top of all that, ABHSSYS is a green transition catalyst in terms of noise and vibration reduction. ABHSSYS's ambition is to train a new generation of 11 expert researchers in the field of vibro-acoustic engineering through an innovative interdisciplinary training programme. The consortium of ABHSSYS includes 7 academics, all specialists of ABH, building an exceptional team and 6 companies representing a wide range of fields of activity concerned with noise reduction under environmental constraint: Aeronautics (AIRBUS, BOMBARDIER), Aerospace
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Current and future shifts of snow regimes in extreme environments' under Horizon Europe.

assistant: **Concept**

The UN Decade of Action on Cryospheric Sciences aims to reduce uncertainties regarding the causes and effects of changes in snow, ice, and permafrost. Snow is a major contributor to these uncertainties due to the incomplete understanding and representation of snow processes in climate models. SnowShifts seeks to significantly enhance our comprehension of snow volume and mass, their non-linear dynamics and properties and, specifically, snow regime shifts within the Earth and climate systems. This will be achieved through a novel combination of in-situ and remote sensing observations, along with high-end numeric model developments. Innovative technologies such as photon-counting space-borne laser altimeters, terrestrial superconducting gravimeters, and novel scale-bridging approaches and downscaling of satellite gravimetry in extreme snow environments will be integrated with the latest multi-sensor satellite data and modelling. This will enable the retrieval of snow volume, mass, extent, and other properties, such as snow albedo, at unprecedented spatio-temporal resolutions. The combined observational and modelling advancements will define and describe trends and shifts in snow climates ranging from high-latitude polar regions to mid-latitude high-mountain ranges. This project will provide future snow scenarios for at least three socio-economic pathways refining current global and regional climate models, exploring and defining potential non-linearities in snow changes. SnowShifts will not only demonstrate the accuracy of our new models in reproducing snow quantities and dynamics, but will also generate extensive datasets characterising snow in remote and understudied regions. The new representations of snow processes will be a major outcome permitting the scientific comm
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Low-cost semiconducting polymers for manufacturing 2D-digital X-Ray detectors' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

This project is about launching a next generation of DEXA bone densiometes incorporating 2D digital X-ray detectors with a lower and affordable price. DEXscAn project proposes to both modify current materials used in DEXA bone densitometers detector, together with a novel manufacturing process for large-array areas: 1. Improve the sensitivity of the devices by substitution of amorphous silicon (aSi:H) FET by cheaper and highly efficient organic materials as photo-detectors. These organic semiconductors are easier to process than Si-detectors, allowing different shapes and sizes, including curved surfaces otherwise impossible to achieve. 2. Substantial reductions in manufacture costs of large-area arrays (2D-digital panel detectors in DEXA scans), by using organic semiconductors P3HT:PCBM, PTAA:TIPS-Pentacene or F8T2, offering the possibility to obtain solution-processable inks, and therefore printing large areas using simple techniques like inkjet printing or screen printing. Our company L´Accessorio Nucleare manufactures first generation bone densitometers since the 70s and since then, we have developed and successfully placed in the market 7 different bone densitometer products, being one of the leader suppliers of high-tech bone densitometers worldwide. With this product and the EC support our company seeks to become the first company worldwide implementing Digital Imaging in DEXA Bone Densitometers and to reduce the final price for DEXA bone densisometers. The aimed prouct will have advantages not only for our current clients (public and private big hospitals that nowdays purchase these devices for replacement of old ones) but also for new clients (smaller hospitals, clinics and ambulatories) where DEXA scans can be used as a regular preventive diagnosis service.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Nanomaterials Ecological Risk Assessment: A study of the long-term effects and risks of nanoscale Iron Oxide used in plastic composites in the aquatic environment' (NanoERA).

assistant: **Innovation**

The nanoform of Iron Oxide (n-Fe2O3) is a large-volume substance used in pigments. Nanoscale Fe2O3 pigments are used to a significant extent in consumer products such as household appliances made of coloured plastic composites. This application implies high probability of n-Fe2O3 release into the aquatic environment (especially during end-of-life processing of the plastics), where n-Fe2O3 may pose risks to freshwater and sediment organisms. Presently, very little is known about the biological interactions and the ecological risks of n-Fe2O3, as the available information addresses only short-term effects of pristine n-Fe2O3. Therefore, the goal of NanoERA is to develop concepts and methods, and to generate data to predict the long-term ecological effects and risks of n-Fe2O3 (fragments) released from end-of-life processing of a coloured plastic composite into the aquatic environment and to compare them to the pristine n-Fe2O3 used to produce the composite. In order to achieve this, the fellow will analyse how the physicochemical properties of the n-Fe2O3 (fragments) change in environmental (i.e. freshwater and sediment) and biological (cell culture) media and how these changes affect the biological interactions of these materials in aquatic organisms. The generated ecotoxicological effects data will be used to derive dose-response relationships and to quantitatively estimate the long-term ecological risks of the n-Fe2O3 (fragments). In the process of achieving the NanoERA scientific objectives the Marie Curie fellow will obtain training in transferable and technical skills. The fellow’s qualification match very well to the research programme, which promises that NanoERA will produce excellent scientific results, which will be broadly disseminated to achieve significant a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'United by diversity - Management policies of cultural and linguistic diversity in Switzerland and Canada : Two reference laboratories for European Union?' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

This project is a continuation of my previous doctoral research into multiculturalism and national identity in Canada, Quebec and France using a comparative perspective. The project goal will be the acquisition of additional skills in the field of political anthropology, and the continuation of my research in order to prepare an Accreditation to supervise research. The implementation of this project requires a period of mobility at the University of Freiburg and my integration within the Department of Political Anthropology where Professor Christian Giordano is committed to supervise my research.Canada and Switzerland are two federations characterized by cultural and linguistic diversity. In both cases, the recognition of this diversity is one of the cornerstones of collective identity. Their respective Constitutions state that one of the primary objectives is the promotion of diversity on their territories. I have chosen to use the phrase: ""united in diversity"" in order to describe these countries which share the same institutional paradigm: the diversity of cultures and languages is an asset to be preserved.The objective of this research is to compare the political management of cultural and linguistic diversity in Canada and Switzerland at the federal and local levels. To do this, we will rely on an analysis of constitutional provisions in legislation and jurisprudence, published sociological and historical analyzes on this subject, as well as some targeted interviews. The term ""consociation"" (Walzer, 1997) used to describe these political regimes characterized by the coexistence of different cultural and linguistic communities within a territory will be preferred to that of a multinational federation, the use of which is more controversial. This comparative anal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Design, synthesis and optimization of Fe(III) based porphyrins for use as next-generation MRI probes'.

assistant: **Innovation**

Magnetic resonance imaging (MRI) plays a pivotal role in early diagnosis and therapy follow-up of many diseases. The substitution of current Gd-based MRI contrast agents (CA), which raise both safety and environmental concerns, is one of todays most important challenges in imaging-related chemistry. High complex stabilities and inertness attainable with Fe(III) make it a high potential alternative to Gd. Porphyrins have met great clinical success, exhibit biocompatibility, stable metal complexes and easy structural modulation., but formation of -oxo-dimers in Fe(III) porphyrins (FePo) reduces their relaxation efficacy. PorphIRON will tackle these limitations and develop new families of biocompatible FePo fine-tuned for MRI use. PorphIRON will focus on structural optimization to i) maintain the oxidation and the high spin state of Fe(III), yielding relaxation effect comparable to clinical CA, and ii) adjust physicochemical properties to preserve biocompatibility. To achieve this, PorphIRON will rely on a synergic combination of the ERs experience in porphyrin chemistry and computational studies with that of the supervisor in MRI CA development, and an iterative approach with: i) initial synthesis of newly designed FePo, followed by their physicochemical and biological evaluation; ii) computational rationalization of the experimental results and prediction of new optimized structures; iii) second-round optimized FePo synthesis and characterization. PorphIRON will deliver fully characterized, stable, biocompatible and high efficacy FePos with preliminary preclinical in vivo MRI validation, thereby actively contributing to the implementation of next-generation non-toxic CA in clinic. PorphIRON will strengthen ERs experience in organic synthesis, computational chemistry, whi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Neural prostheses' (1998-2002), addressing dissemination and exploitation.

assistant: **Impact**

Young researchers attached to the neural PRO project will have the opportunity of performing independent, high quality research with acknowledged experts active in the engineering, biological, medical, and industrial spheres. Not only will they attain a deeper understanding of their own discipline but also, through visits and secondments to other groups in the network, they will broaden their knowledge of, and competence in, all the related activities. They will be exposed to a custom-designed training programme that includes special courses and workshops. They will have the chance to discuss their research in a multidisciplinary context at the regular network meetings, and will be encouraged to participate in international conferences and to publish their findings in international peer-reviewed journals. They will emerge from the programme able to communicate and to cooperate efficiently with researchers from other engineering disciplines, medical sciences and industry. The value of such a training is not restricted to the biomedical field, but will enhance the ability of these individuals to benefit from career opportunities throughout research and industry. (TEXT MISSING)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Structuring of the building energy innovation offer and the technology transfer in the Midi-pyrenees region' in the context of a Seventh Framework call.

assistant: **Objectives**

According to the European Commission expertise, the building sector accounts for nearly 40% of the EU total energy consumption. In this context the implementation of new technologies in the building industry is crucial as far as the energy efficiency objective is concerned.   The InCITE project aims to establish a regional cluster in the field of building energy. It will constitute the innovation, construction, industry and environmental technology center (InCITE). The project will be based on the public-private partnership between ARMINES research entity, the AGATE local economic development agency and the TBC private company specialized in the construction innovation. The project management will be assured by the AGATE agency on behalf of the General Council – the local authority. The project partners aim to set up a cluster that will correspond to the local market profile and that will cover all necessary competences from generating ideas into the industrialization of products in the domains of renewable energies, building intelligent management, dynamic isolation, thermal isolation, natural insulation, new building materials and new construction methods.  The cluster will be open for any other institutions and enterprises interested in the building energy efficiency issues. Therefore one of the most important project tasks will consist of communication and creation of a regional network.   InCITE Project will become a regional development tool that will contribute to the growth of employment and entrepreneurship. By promoting the sustainable development in the energy sector and innovation, the project will also have a positive impact on the European level. The project web site will be available in English version so that it could be consulted by actors from other Eu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Static and Dynamical Description of Correlated Nuclear Systems' (SDDCNS).

assistant: **Innovation**

Our knowledge of nuclear physics is widening thanks to the availability of radioactive ion beams (RIB). These give access to previously unknown regions of the nuclear chart and unveil new properties of atomic nuclei and their constituents, the nucleons (neutrons and protons). RIB experiments have found previously unknown nuclear phenomena, providing exciting challenges for theoretical nuclear physics. Among these, one should make an effort in understanding how the properties of nucleons are modified inside exotic nuclei. This can only be assessed with a proper treatment of nuclear correlations beyond the mean-field approach. In this proposal we focus on two particular subjects of relevance in the context of nuclear theory for RIB facilities. On the one hand, we would like to develop a time-dependent formalism for the description of central low-energy reactions including the effects of correlations. To this end, we will study the Kadanoff-Baym equations, which account for the time-evolution of nucleon propagators in the nuclear medium. These equations are quantal and offer a consistent theoretical framework to include different processes in the description of reactions. In spite of their potential applications (even for nuclear structure properties), they have been applied scarcely to finite nuclear systems. On the other hand, we plan to perform realistic many-body calculations to understand how correlations change with the increasing isospin asymmetry of nuclear media. In contrast to the somewhat phenomenological extrapolations inherent in mean-field theories, microscopic many-body approaches have a good handle on isospin asymmetry. The Self-Consistent Green’s Functions theory can, in particular, describe isospin asymmetric correlated nuclear systems and offers a unique