RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Commercialising a novel glioblastoma targeted therapy and a companion diagnostic compound' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Glioblastoma (GBM), is the most aggressive form of primary brain cancer and is diagnosed in 22,000 people per year in the EU. GBM is the most aggressive primary brain cancer and, by annual incidence, the most common type of malignant brain tumour. Despite aggressive treatment, the cancer always recurs. The average survival after diagnosis is 12 to 15 months, with less than 3% to 5% of patients surviving longer than 5 years. The current standard of care extends overall survival to ~14 -16 months. Current valuation of the global GBM treatment market is estimated to be €615 million per year, and it is predicted to increase to over €3.08 billion by 2024 (compound annual growth rate of 17%), based on the projected approval of new therapies including Opdivo and Optune. The main aim of this ERC PoC proposal is to probe the commercial viability of two types of tumour-targeted payload hybrids, one as an improved chemotherapeutic treatment, and the other as a precision-guided imaging agent for PET/MRI-based diagnosis. Our goal is for the former to become the clinician’s chemotherapy of choice in the adjuvant phase of GBM treatment; and for the latter to be incorporated into PET and MR-imaging procedures as a method for identifying and diagnosing GBM, as well as a companion test for stratification of patients for therapy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Photorhabdus Action for Grapevine Protection' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

The fanleaf virus nematode, Xiphinema index, is the Grapevine Fanleaf Virus (GFLV) vector, the leading cause of the most severe viral disease in grapevines worldwide. By feeding on the root tips of actively growing grapevines, nematodes can cause a 40% root mass loss, facilitating the acquisition and transmission of GFLV and significantly reducing crop yield —up to 80%— and grape quality. Currently, no direct control methods are available for these intracellular pathogens, so management efforts focus on monitoring and controlling the fanleaf virus nematode using hazardous chemical pesticides. There is an urgent need for innovative control strategies that enhance vector management, mitigate the impact of intracellular pathogens, and improve viticultural sustainability worldwide. The cosmopolitan endosymbiont Photorhabdus (Morganellaceae) bacteria produces a wide range of natural compounds with multiple functions in the soil. PhotorActVine hypothesized that Photorhabdus strains might potentially protect grapevine plants against the fanleaf virus nematode and its global damage while also being capable of colonizing grapevine roots and enhancing the plants' growth and defence mechanisms. PhotorActVine proposes an innovative, ambitious, and feasible project, which includes i) identifying Photorhabdus strains with the highest nematicidal ability, ii) training these bacteria to adapt to grapevine rhizosphere conditions, iii) reducing the damage caused by fanleaf virus nematode and its damage through the application of evolving Photorhabdus strains in the grapevine roots, and iv) identifying the mechanisms involved in the interaction between Photorhabdus and grapevine plants. This multidisciplinary approach will enhance and integrate our understanding of the efficacy and mechan
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Towards lossless electrical energy converters' under Horizon Europe.

assistant: **Concept**

Electrical energy is typically converted four times between source and load, by over 100.000 GW installed converters. Over 99% efficiency is already reality, e.g., in PV inverters, however in a trade-off with power-density and complexity. Thus, most converters stay below the technical performance limits. Incremental advances in semiconductor technology will continuously push these limits’ values, but does not fundamentally change it.This project takes a disruptive approach, investigating partial-power-processing (PPP): Recently, we operated a 99%-efficient 2-level half-bridge in a multilevel topology, increasing the external capacitive-load charging voltage and power 6-times, while keeping the inner losses almost constant. From 2 to 7 level operation monotonically improved the system efficiency from 99% to over 99.7%. A global maximum was not yet reached. PPP theoretically reduces the losses by a factor of N, if only 1/N of the power is converted by a lossy converter while most power is delivered directly to the load by almost-lossless bypass switches from energy buffers.The question is: ""How can electrical conversion efficiency be further increased with partial-power-processing, targeting 99.9% for selected loads?”To approach this “lossless” energy conversion, we will (1) theoretically further investigate PPP and many-level converter topologies, semiconductor devices, and operation parameters, (2) design and characterize converters with two cascaded stages of internally already PPP converter-submodules in a novel way to further improve the system efficiency 3 times (to 99.9%). We will investigate (3) low-voltage (< 100 V), medium-voltage (< 1000 V) and high-voltage (< 10 kV) PPP converters, and cascade them to multiply their benefits. (4) Application to selected, init
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Humanitarianism and Mediterranean Europe: A Transnational and Comparative History (1945-1990)', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

In recent years, international humanitarianism has increasingly attracted the interest of historians. A great deal of research has reconstructed aid programmes for those who are victims of war, natural disaster or economic disadvantage. These studies have mainly examined the experience of donor countries in northern Europe, as well as the United States, while the countries of southern Europe have largely been overlooked. HumanEuroMed challenges this unbalance. It puts the countries of Mediterranean Europe at the centre, and it explores the experience of different actors (institutions, administrators, experts, non-governmental organisations) in a comparative and transnational perspective. This project seeks to reframe the history of international aid in the second half of the 20th century by restoring to view the contributions of Mediterranean Europe to shaping the contemporary humanitarian regime. It will achieve this objective by addressing three thematic axes which are able to capture the specific humanitarian undertakings of the countries under investigation (Portugal, Spain, Italy, Yugoslavia and Greece) and make them comparable: 1.the entanglements between international aid, decolonisation and the complex configuration of the post-colonial world;2.humanitarian diplomacy and the transnational networks (both formal and informal networks, between institutions, non-governmental organisations, professionals and experts) that interconnected the countries of Mediterranean Europe between themselves and to the Global South;3.the linkages between international relief and national welfare, with a focus on the intertwining of policies, practices and cultures of social care on a national level and those of international relief programmes.HumanEuroMed will contribute to paving t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Pledge Limits Evaluation for Decarbonization: Goals of the EU27 Strategy' under Horizon 2020.

assistant: **Concept**

This research aims to develop a new climate policy modelling tool - PLEDGES - which manages, for the first time, carbon budget targets for EU-27 countries. Each EU country has different barriers and opportunities for decarbonization. However, these potentialities are not exploited nor explored by the EU Green Deal or by the long-term mitigation targets established under the United Nations Conference of the Parties Agreements, which pledged to keep the temperature increase below 2°C. Current EU policies mainly focus on emission reduction targets and do not take into account cumulative emissions or the speed at which the transition to lower carbon can be achieved. Considering these factors is critical to the success of policies that can achieve the temperature goal. PLEDGES model will fill this gap, providing EU policy-makers with a tool able to downscale EU and world climate mitigation policy to national levels. It will set a European carbon budget and allocate an allowance of carbon emissions to each EU region, country, or even person according to a set of eligibility criteria based on an effort-sharing approach. Once a potential carbon budget for each member state is calculated, the PLEDGES tool will be able to simulate necessary deviations from the assumed national quotas and to evaluate how those deviations impact on the other member states. PLEDGES will help policy-makers evaluate accurately the shared effort needed to mitigate climate change; it configures as a high interdisciplinary tool, helping in designing mitigation actions under a holistic view that considers topics in scientific, economic and social spheres, including the role of gender.


**Keywords:** Carbon budget, decarbonization, climate change, climate mitigation, EU Policy, COP21, greenhouse, gases, e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Neuronal implementation of cognitive maps for navigation' (COGNECTOMICS) under Horizon Europe.

assistant: **Objectives**

Intelligent behavior is based on internal models of the world that enable mental simulations and strategic planning. A leading model to study such “cognitive maps” are networks of place cells and grid cells in the mammalian hippocampal-entorhinal system. These neurons are active at defined locations and collectively represent a physical environment as a low-dimensional topographic map in neural activity space. However, a mechanistic understanding of the underlying computations and their biological implementation remains elusive. Using new methods for brain-wide activity imaging during behavior, members of our team discovered an abundance of place cells in the telencephalon of zebrafish. We will combine this approach with volume electron microscopy to reconstruct large-scale connectivity in the same brains at synaptic resolution and with transcriptomic profiling to identify molecular cell types, taking advantage of small brain size. The joint analysis of network connectivity and population dynamics will allow us to determine how functional properties of place cells are established by interactions between specific subsets of neurons across brain areas, and how network structure constrains population activity to topographically organized attractor manifolds. The results will disambiguate computational models that make conflicting assumptions about network connectivity. We will further explore the emergence of cell types during development and the concomitant structural and functional maturation of neuronal circuits. The relevance of cognitive maps for neuronal computations and behaviors involving internally generated predictions will be explored by activity measurements in a virtual reality and by functional manipulations of genetically targeted neurons. Capitalizing on th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Uav civilian application workshop: environment/communication/safety'.

assistant: **Concept**

This proposal is a request for funding a workshop regarding the subject of Civilian Applications of Unmanned Airborne Vehicles (UAV' s). The emphasis of the workshop is to increase the awareness in the European community regarding the rationale and the benefits of potential civilian missions using UAV's. The importance of safety and certification will be stressed and the relevance to the fields of communication and environment will be discussed. Invited lecturers will complement panel discussions and brainstorming sessions" to insure maximum success of the workshop.The workshop is related to Measure 2 of the Accompanying Measures:"Studies in preparation for future activities" and Measure 4: "Awareness, assistance and information exchange actions"."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Re-deployable solar boilers based on concentrating solar collecotors for ESCO type sale of thermal energy to industrial processes.'.

assistant: **Innovation**

Our SME project addresses the vast and under-served market for solar process heat, defined as the provision of solar-generated heat to industrial thermal processes up to 250°C. This market is worth more than 26 billion €/year, with a current penetration rate of traditional solar thermal technologies of less than 0.02%.Our business idea eliminates any risk for the end user thanks to a first-of-its-kind business model which can be implemented only by exploiting our company’s unique set of achieved and planned technical developments on concentrated solar thermal systems.We will develop cost competitive re-deployable solar boilers, i.e. turn-key and easy-to-install concentrating solar thermal systems of at least 1MWt which can be used to sell heat (as opposed to equipment) to our target customers. Industrial users rarely want to commit to long term heat purchase contracts. Re-deployability and competitive cost enable us to offer minimal initial commitment (only 3 years) for the purchase of solar heat. Afterwards, if the client is happy he will continue to buy the energy, otherwise we can take the system back and re-deploy it (i.e. use it again at a different user’s site). This highly innovative commercial approach, made possible by the technological breakthrough of the system’s re-deployability, will boost market penetration.We will demonstrate the soundness of the proposed business concept by implementing - at real industrial sites in target geographic segments - two distinct pilot installations of approx. 2’500 m2 of net collecting surface (i.e. more than 1MWt) each, one with Fresnel and one with parabolic collectors.Market replication will be pursued by means of active communication to other potential users, and also to institutional and financial stakeholders. These com
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Integrated Standard Imager for Earth Observation Microsatellites' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The project brings to the market iSIM: A compact high-performance camera for Earth Observation satellites that is at least 3 times smaller (8 Kg), more affordable, and with 3 times shorter delivery times (90 days) than equivalent solutions, combining a straightforward design (patents pending), with advanced electronics and software, and serial manufacturing standards from its conception.ISIM, provides the best multispectral spatial resolution of the market (0,55 m GSD) in a small payload that fits in a microsatellite (10-100 kg) reducing in an order of magnitude the Earth Observation total mission costs. This innovative product has generated an outstanding interest among leading prime contractors, like Airbus Defence & Space, emerging Microsatellite Manufacturers, like Berlin Space Technologies and GomSpace, space systems integrators, like Deimos Space and Everis, and Earth Observation data users, like Telefonica. More than 2100 small Earth Observation satellites will be launched in the next decade, 8 times more than between 2006-2015. SATLANTIS aims to capture 28% of the 20-100 kg micro satellite segment in the next 8 years. To do so it will offer ISIM in two sizes (ISIM-90 and ISIM-170) tailored for two micro satellite market segments (20-50 and 50-100 kg mass). SATLANTIS is a young technology SME, promoted by a group of high calibre engineers and scientists, that connects the three vertices of the “triangle of knowledge” –universities, industries, and government– to become the leader in Earth Observation payloads for small satellites. The Spanish company, has recently closed a 2.35 M€ funding round with four industrial investors and venture capitalists. Combining this round with the SME-2 project, SATLANTIS can validate its product early in Space and achieve break-ev
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The evolution of the Grassland biome: exploring past events to predict future scenarios' (GRASSLANDS), addressing dissemination and exploitation.

assistant: **Impact**

Knowledge of the evolution of the grassland biome throughout the Earth's environmental history is important for the reconstruction of links between diversification/extinctions events and climate. Biomes are now being impacted by anthropogenic environmental change on an unprecedented scale, and one mean of understanding how component species will react is to study the effects of past environmental changes. Hence, understanding the evolutionary history of grassland ecosystems in the context of past biotic and abiotic changes is relevant to the way we will manage them under future environmental change. A new perspective on the history of the grassland biome is beginning to emerge from key developments in palaeontology and molecular phylogenetics that will be integrated interdisciplinary and multidisciplinary in the present project for the first time. GRASSLANDS aimed at understanding the timing and nature of grasslands' most important components, the grass (Poaceae) and daisy (Asteraceae) families, through the combination of fossil data, molecular phylogenetics and computational approaches. The potential contribution of GRASSLANDS to our understanding of the evolutionary history of these families and grassland ecosystems in general is significant and will certainly provide new insights into the rise of flowering plants as the dominant components of almost every terrestrial ecosystems.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Valorising magnetometry in cells' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Magnetic resonance spectroscopy (NMR or ESR) and magnetic resonance imaging (MRI) are widely used. However, magnetic resonance signals are low in energy and thus difficult to detect.  These techniques are expensive and  typically only offer millimeter down to micrometer resolution. Diamond magnetometry potentially offers a solution. The technique is based on a quantum effect and allows even the detection of single electron spins. While the technique is already used for a few years in physics, during my ERC project this powerful tool was utilised for the first time to measure metabolic activity in living cells.The aim of this project is to explore the commercial potential of these results and - if it is deemed feasible - found a start-up company for exploitation. As a first application we will investigate free radical generation. These molecules play a key role in many biological processes including cell communication, immune responses or ageing. Additionally, they are an indicator for stress and thus play a role in many diseases including cancer, cardiovascular diseases or viral and bacterial infections. Despite their relevance and the fact that free radical generation is often an early sign of disease, they are rarely used as biomarkers since they are notoriously difficult to measure. In this project we will build a prototype (to be patented) that can be used for demonstrations to customers. This will be done on close collaboration with a user committee in order to meet the customer expectations. To demonstrate the usefulness to customers for diagnosis we will conduct test measurements . Further, we will assess whether a business model based on a product or based on services or a hybrid business model containing both is most promising.