RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Deciphering the evolution and roles of cytosine DNA methylation across eukaryotes' (METHYLEVOL), addressing dissemination and exploitation.

assistant: **Impact**

Cytosine DNA methylation is a major component of eukaryotic chromatin, yet extensive variation of methylation patterns occurs throughout eukaryotes. So far, the roles of DNA methylation have been mostly characterized in vertebrates, plants and fungi, where two common patterns have emerged as potentially ancestral within eukaryotes: methylation of silent transposable elements and methylation of constitutively transcribed genes (gene body methylation). However, the genes responsible for depositing methylation are not always orthologous across divergent lineages, so these common patterns could instead be the product of convergent evolution. To discern between these alternatives, we first need to correct the taxon sampling bias that hampers our understanding about the evolution of DNA methylation.In this project we will determine the roles of DNA methylation across vastly underexplored eukaryotic diversity. We will use state-of-the-art genomic techniques, experimental manipulations and computational analyses to trace the evolutionary conservation of methylation-dependent transposable element silencing across a wide range of unicellular eukaryotes, using methylation-depleting drugs and bisulfite sequencing. We will then assess the roles of gene body methylation in an invertebrate to unveil similarities with plants and shed light on why vertebrates transitioned to hypermethylated genomes. Finally, we will study the evolution of proteins able to bind and interpret DNA methylation across disparate eukaryotes, since ultimately these proteins link DNA methylation and its regulatory functions.Through linking experimental epigenomics to macro-evolutionary comparative genomics this project will reveal how different functions of DNA methylation assembled throughout evolution. In turn
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'ADDitively manufactured limited angle torque MOTor for Smart Active Inceptors' to be submitted under Horizon 2020.

assistant: **Abstract**

The main objective of ADDIMOT project is to investigate additive manufacturing (AM) technologies to design, and manufacture a new generation of electrical torque motors for their application in Smart Active Inceptors (SAIs). This new generation of motors shall demonstrate better performance than the traditional solution in terms of weight, power consumption, torque density, cost and compactness of the design.For this purpose, this main objective splits into the following technical objectives:•Investigation on the most suitable materials for additive manufacturing of electric motors, attending to soft and hard magnetic, electrical, mechanical and thermal properties.•Electromagnetic and mechanical design of the active parts of electric motors for smart active inceptors, mixing different materials and looking into new 3D geometries enabled by AM technology.•Comparison of new concepts of active components enabled by AM with traditionally manufactured parts. Evaluation of electric motor concepts using fully AMed parts, fully traditional manufacturing and hybrid (AM + traditional) manufacturing.•Electromagnetic and mechanical topology optimization of the evaluated electric motor concepts, in terms of weight, power consumption, torque density, cost and compactness of the design.•Development of manufacturing criteria for the AM of electric motor components.•Design and manufacture of three electric motor demonstrators using AM technology
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Compact SOI nanophotonic Raman Laser and modulator and detector based on circular grating resonator devices'.

assistant: **Concept**

The present project aims at the development of very advanced all-silicon based nanophotonic devices clearly beyond state of the art in terms of functionality, size, speed, cost and functionality. Common component of the envisaged devices are silicon-on-insulator (SOI) technology based circular Bragg resonators with very high quality factors for a concomitant increase of integration density and device efficiency. In particular, the project will realize an approach for a highly compact silicon Raman laser source, a high-speed silicon electro-optic modulator and a novel approach for resonant signal sensing in SOI waveguides. A further increase of packing densities is aimed by the integration of a multi layer SOI waveguide development.To reach the ambitious goals of the project, the focussed effort will be guided by substantial design and modelling activities, optimizing the electro-optic response functions of each sub-component. For an improvement of device performance compared to the state-of-the-art, precise control of free carrier lifetimes in these devices is envisaged by the implantation of ultra-fast recombination centres. Device fabrication strongly relies on low-cost, mass fabrication compatible nanolithography technology based on high-precision UV-Nanoimprint.A possible route to monolithically integrated silicon photonic will be demonstrated to enable new device concepts for communication, automotive, infotainment and biomedical system in the future. Therefore, the project activities are expected to have a profound impact on IST-related technologies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Towards TOPological insulator-based electronic devices for ROOm Temperature operation' (TopRooT), addressing dissemination and exploitation.

assistant: **Impact**

The proposal TopRooT (Towards TOPological insulator-based electronic devices for ROOm Temperature operation) aims at providing a route to novel electronic devices based on topological insulators. Nowadays, most of the research on topological insulators is for cryogenic (quantum)-electronics, but they also show huge potential for room temperature applications. To this end, a crucial technology is the integration of topological insulators (TIs) with topologically-trivial materials, such as ferromagnets (FM), enabling applications in spintronics and beyond. The proposal focuses on the study and optimization of TI/FM heterostructures and their application in spin-orbit torque magnetoresistive random access memories (SOT-MRAM). SOT-MRAM is at the forefront of the emerging technologies that enable a new generation of brain-inspired and energy-efficient computing, extremely relevant to drastically decrease the energy consumption of information and communication technologies, as stated in the European Commissions strategy on Shaping Europes digital future.State-of-the-art implementation of SOT in TI/FM heterostructures is achieved at the microscale, which is not enough to achieve the needed high density of devices. Therefore, the proposal will specifically target the fabrication of nanoscale TI/FM heterostructures and pursue their implementation in full nanoscale magnetic tunnel junction (MTJ) devices for SOT-MRAM, addressing the integration and efficiency challenges that arise. This will be achieved by growing Bi2Se3 (the chosen TI system) by molecular beam epitaxy and by sputtering the FM and MgO layers for the MTJs. Nanoscale fabrication will be achieved by electron beam lithography and auxiliary techniques. The efficiency of the SOT in TI/FM heterostructures will be accurat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Identification and targeting of somatic changes initiating sporadic cancers'.

assistant: **Objectives**

Cancer drugs are extremely ineffective, generally because current therapies do not address cellular heterogeneity. While hypothesis-driven research and functional genomics identify ever more novel putative therapeutic targets, the scientific community lacks rationales to attack the cellular heterogeneity in cancer, to select among the targets the most promising, and to design combination therapies. In particular, these all fail to provide successful adjuvant therapy settings after curative resection of the primary tumour before the onset of manifest metastasis.Here I propose a novel way to address cancer cell heterogeneity and to develop a rationale for the design of adjuvant therapies. The proposal rests upon the premises that (i) cancer initiation is causally associated with genetic changes, (ii) early, functionally relevant genetic changes -particularly involving DNA loss- have the highest probability to be shared among the progeny of a monoclonal, yet genetically unstable, cancer, and (iii) subsequent, cumulative genetic changes must either add to the fitness of the cell or at least be neutral to enable progression. The proposal is then built upon our observation that a subgroup of disseminated cancer cells (DCCs) displays normal karyotypes and DNA changes smaller than 10 Mb whilst primary tumours and more advanced DCCs harbour multiple additional chromosomal changes at the time of analysis. I suggest that although these karyotypically normal DCCs are the putative “loser cells” in cancer progression - since they are arrested in bone marrow - they are central to uncovering the early genetic changes of an individual cancer. With these cells we will identify for the first time the catalogue of initiating changes of sporadic cancers in a systematic way. We will then tes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Internet of Thing for Smart Water Innovative Networks' (IoT4Win).

assistant: **Innovation**

The IoT4Win will establish a European Industrial Doctorates (EID) training program and extend the traditional academic research training setting, equipping researchers with right combination of research-related and transferable competences, joint research training programme combines an interdisciplinary expertise of European research group, industry partners and user organisations, bring together all required knowledge, skills, and stakeholders to offer a comprehensive set of transferable skills and a training programme on ICT, data science and water engineering, including industry practice and longer-term benefit in further industrial partner collaborations and further knowledge transfer. IoT4Win will respond to well defined and interdisciplinary scientific questions and challenges on IoTs for Smart Water Network (SWN) technological area cooperating  to recruit 3 ESRs to undertake research in the context of a joint research training on concepts and methodologies of IoT enabled SWN towards the PhD. IoT4Win designs 3 individual and personalised research projects covering the core SWN research areas, i.e. smart sensing and trusted communication within energy limited heterogeneous devices in IoT enabled urban water environment;  dynamic sensor web and interoperable open platform with Integrated Knowledge Management for smart water networks; data security and  intelligence in IoT enabled SWN. The interdisciplinary collaborations and cross industrial interactions between ICT and water sector, will expose researchers to the academic, non-academic sectors. By combining three projects, an interoperable, secure and intelligent underlying technology leading to an open platform for IoT enabled SWN applications will be developed. This platform will then be applied to and evaluated
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Discrete topological and conformal quantum field theory through combinatorial factorisation algebras' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

This project will contribute to our understanding of mathematical Quantum Field Theory (QFT) by formulating a discrete version of Factorisation Algebras (FAs). This will be used to solve an open conjecture about Topological QFT (TQFT), describe and establish dualities between QFTs, and form a bridge between discrete and category-theoretic techniques for Conformal Field Theory (CFT). FAs are among the most flexible approaches to mathematical QFT, but no description as FAs of discretised QFT is known. This project's combinatorial FAs (cFAs) fill this gap. They have many applications, three of which will be covered in this project.The first is to prove that the discrete state-sum models for Topological QFT (TQFT) give rise to Functorial Field Theories by fitting state-sum models into the sFA formalism and establishing a continuum limit result for topological sFA. Functorial Field Theory (cf. Atiyah, Lurie and many others) is a formalism for QFT that is particularly popular for TQFT. While this conjecture has been around for over 20 years and is believed to be true no proof exists. Secondly, I will use techniques from duality for sheaves and cosheaves on simplicial complexes to prove a duality result for sFA analogous to Poincaré-Koszul-Verdier duality. Lattice models are a source of interesting dualities between QFTs, such as the Kramers-Wanier self-duality of the Ising model. These dualities will be shown to be an instance of sFA duality, and this description will be used to find new dualities for physically relevant QFTs. Associated to these dualities are defects which are intensively studied in theoretical physics.Thirdly, cFAs will be used to give a FA description of the discrete QFT known as the Ising model. This will be linked with Discrete Holomorphicity techniques
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'A New Concept For A Fully Integrated Wound Assessment And Monitoring System' to be submitted under Fifth Framework.

assistant: **Abstract**

The objective of our work is to produce an integrated system for the measurement, interpretation and recording of chronic wounds with which to improve the targeting and management of their treatment. This will reduce patient suffering and healthcare cost.Work description:The Work will incorporate the following processes: Innovative development of a vision system with built in co-ordinate management system for reliable automatic discrimination and measurement of the major wound physical features such as depth and granularity.Milestones:The key milestones are Build the Neural Net system - month 6;Novel E-nose operational by month 11;Vision system working by month 12;With a fully functioning prototype system starting final validation trials month 19.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Welfare on the Move: Female Mobility and Social Care Across the Early Modern Adriatic' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

The WelMovFem project explores the interrelation between human mobility and access to pre-modern welfare within the Republic of Venice (from the 16th to the 18th century). The overall objective is to highlight the role of migrant women as both providers and recipients of social protection, focusing on their translocal networks and possessions. Could their geographical mobility influence their capacity to demand certain rights, or otherwise affect the institutions’ abilities to verify the legitimacy of their claim? To answer this question, the research will not be limited to urban charity institutions, but will encompass various forms of aid that moved between Venice and its Eastern Adriatic domains (e.g., financial aid, inherited possessions, dowries, and slave ransoms). Intertwining a quantitative analysis and an in-depth study of the sources will be essential to uncovering the significance of women’s material resources in empowering kinship, family, and community ties even across great distances. Through the adoption of an interdisciplinary approach, which combines gender history with mobility studies and digital humanities, the WelMovFem project will result in an innovative and ambitious vision of social care in a region that connects various facets of European culture. The research data will be accessible to scholars and the wider public through a web digital platform for the humanities, which will provide a starting point for future research. The project’s ultimate aim is to enrich ongoing discussions about migrants’ rights from a historical perspective, enabling EU policymakers to have a long-term view of the current migratory phenomena and raising EU citizens’ awareness of these global issues. The researcher’s mobility between various academic settings (the US, I
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Elaboration of a strategy for the transition from eatchip phase iii to the European air traffic management system.'.

assistant: **Objectives**

The main objective of this work is to produce a transition strategy which enables the evolutionary development from the EATCHIP Phase III ATM systems to the future European ATM system. A good transition strategy means that the transition over time can be effected efficiently in terms of investment, required man-power and through life costs of future ATM systems.Our proposal starts with the definition of a set of principles, or transition concepts. These principles will define how transition concerns are to be handled; for example concerns about geographical area, consistency between states and standards and refulations. Dimensioning points are the constraints that impact the performance of transitions, for example, human factors and validation processes, and these will be developed alongside the transition concepts.With the transition concepts and dimensioning points in place, a further pbjective of this work is to initiate the transition process through the provision of transition actions. This objective derives from the acknowledgement that on the one hand EATCHIP Phase III issues are well know and understood, yet on the other hand the options for EATMS are many and far from being understood fully. Therefore, initiating the transition process and making it iterative provides an appropriate basis for the development of a realistic transition strategy, this being the consolidation of the transition actions, their sequencing, prioritisation and consistency across parallel system evolutions. %
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'New Insights on Micrometeorites' (MICROMET) under Seventh Framework.

assistant: **Objectives**

Micrometeorites are extraterrestrial dust particles that reach the Earth’s surface. They largely originate from comets and asteroids, the small bodies of our solar system believed to contain primordial solar system materials in a range of states of preservation. The mineralogy of these materials provides a record of their formation environment (e.g. temperatures and materials available) and/or subsequent parent body processing they experienced since accretion (e.g. exposure to water or heat). Therefore, the study of micrometeorites can provide valuable information regarding conditions in the early solar system and evolution of the small solar system bodies from which they originate. Micrometeorites constitute more incoming mass of material and sample more parent bodies than the larger meteorites, yet much less research has been done on them as their small size has made analyzing and collecting them difficult until relatively recently.We propose to systematically characterize and compare new micrometeorites from the South Pole and a unique collection from Kwajalein with the aim of gaining new insights into the formation, evolution and current state of small solar system bodies. We will use state of the art facilities to prepare and analyze these particles in order to identify and interpret rare or unusual micrometeorites that represent previously unsampled parent bodies, understand atmospheric entry alteration and terrestrial weathering effects, and determine the sources (asteroid or comet) and flux of micrometeorite types with time.The proposed work will transfer the Fellow’s expertise in small sample preparation and analysis to the Natural History Museum and expand its repertoire of extraterrestrial material studies.  This will reinforce Natural History Museum’s reputa