RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Application of solar waste water detoxification and disinfection systems in the mediterranean and developing countries' (1994-1998) under Fourth Framework.

assistant: **Objectives**

Research objectives and content The general objective of the joint research training is to assess the market situation of developed solar photochemical technologies for water detoxification and disinfection. Options to improve the water situation of arid zones will be worked out. The formerly achieved research results will be transformed from a model character into the handling of real waste water and the feasibility of solar purification for specific industries and greenhouse companies. The waste water tests will be carried out using the existing small scale facilities at the Plataforma Solar. In case of promising results there will be initiated the planning and construction of first industrial scale solar purification plants in cooperation with the relevant industries and engineering and supplying companies. The applicability will be shown for the region of Almeria as a representative area for the Mediterranean and developing countries. Training content (objective, benefit and expected impact) Practical experience in acquiring industrial contacts for research establishments and coordination between | industry and research will be trained. Further experience in the operation of solar photochemical facilities and the evaluation and dissemination of the results of degradation tests is expected. Links with industry / industrial relevance (22) This proposal aims at proving the feasibility for solar purification in close cooperation with industries. | The build up of first purification plants will be initiated.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Attracting Postdoctoral Researchers in any Research Field to the Basque Country' (WOLFRAM2).

assistant: **Innovation**

Europe is in need of highly skilled researchers: an adequate supply of skilled human resources is vital for the European Research Area (ERA) development. More specifically, the COVID-19 pandemic has particularly damaged the career of early career researchers in Europe since job opportunities for them are rapidly diminishing during the pandemic. We cannot afford to lose a generation of early career researchers since they are the future of European science and technology-intensive economic sectors. WOLFRAM2 will recruit excellent junior researchers and equip them with the skillset to: i) answer to the need of the ERA, ii) fulfill the UN Sustainable Development Goals, and iii) contribute to the RIS3 strategy of the Basque Country.WOLFRAM2, which will run for 60 months, is framed around an already well and successfully established postdoctoral fellowship programme in the Basque region. Within the programme, the beneficiary, Ikerbasque, will offer 36 fellowship positions for incoming postdoctoral fellows of any nationality. Each fellowship/contract will last for 60 months, being implemented in the framework of WOLFRAM2 36 months. The remaining fellowship duration not covered by WOLFRAM2 (24 months) will be fully taken over by the hosting institutions and Ikerbasque on all terms (financial, training and supervision). The fellowship will be carried out at the 23 partner organisations which recruit and host the fellows. Each fellowship will be complemented by a secondment of up to 6 months at institutions outside of Spain, from a different sector, and of the fellows’ choice in line with their career development plan. WOLFRAM2 offers unique features regarding working and employment conditions, neither provided by other research private foundations or the Spanish government: 5 ye
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Elucidating the phenotypic determinants of hybrid vigour' (PHENOVIGOUR) under Horizon 2020.

assistant: **Objectives**

How organismal traits are inherited in offspring is a long-standing, open question. Hybrids between unrelated individuals of plants or animals often show greater vigour, disease resistance, and fertility. The genetic mechanisms behind the deviation of hybrids from the parental phenotype have been widely studied. However, hybrid vigour remains difficult to predict qualitatively and quantitatively. A key bottleneck is that it remains difficult to explain why different traits are inherited differently. I will overcome this bottleneck to explain trait inheritance and predict hybrid vigour in crop plants from a phenotypic stand point. I will do this by bridging old evolutionary principles with modern models of ecological theory, via the following three objectives: 1. Determining whether in hybrids the degree of trait deviation from the parental phenotype increases with the degree of trait integration; 2. Testing whether modelling relationships between traits can quantitatively explain hybrid vigour; and 3. Building a predictive model of hybrid performance in the field. My project will build on a combination of comparative, experimental and modelling approaches, and a large collection of available phenotypic data in crop plants. In addition, I will use cutting-edge phenotyping facilities to test underlying hypotheses on two experimental species: maize (Zea mays) and sorghum (Sorghum bicolor). The novel hypothesis is that deviation of a trait in a hybrid is the geometric result of the nonlinear effects of traits at lower levels of integration. The objectives are designed to provide a timely breakthrough in the fundamental understanding of variation in trait inheritance. Further, my approach will also enable predictive models of hybrid performance in crop plants to be developed
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Brain Imaging Return to Health' under Seventh Framework.

assistant: **Concept**

Extended lifespan is a new and permanent feature of human life globally. The demographic for population growth of persons over 60 years is predicted to expand by 70% and 400% respectively in developed and less developed regions during the coming decades. Ageing, is accompanied by cognitive decline and greater risk of depression and anxiety. Major drug companies have recently cutback significantly on development of drugs against brain disorders due to lack of new avenues of research. Thus the responsibility falls on academic labs to make breakthroughs to improve brain health.This consortium gathers experts on molecular mechanisms of age-associated pathologies including depressive disorders and anxiety, and neurodegeneration. Specifically, they focus on identification of stress-regulated molecules provoking neuronal death and hindering neurogenesis, and monitoring the consequences of these processes in human brain.The groups combine biological and medical imaging techniques with behavioral studies and proteomics to define molecular mechanisms of ageing and neurogenesis. Using biotechnology, they will create new tools to isolate neurogenic cells from aged brain, thus aiding research strategies an early stage. Four leading imaging infrastructures from across Europe selected from the ESFRI Eurobioimaging Proof-of Concept list have been selected as partners to facilitate this training and research program. Confocal and high-content imaging is used to define ageing pathways, proteomics and genomics to visualize effectors of pathological ageing, transgenic mice to study neurogenesis and MRI/MRS to identify and localize new depression-related parameters in select patient populations. This multi-faceted approach aims to (i) identify druggable targets and identify reagents to inte
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Enhancing the interoperability of cyber-physical systems within their digital supply chains', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Cyber-physical systems (CPS) combine physical and cyber components, enabling dynamic interactions essential for process operation. CPS enhances adaptability of the supply chains capturing, analyzing, and feeding data back into the system. Supply chain adaptability aligns with the efforts defined as a strategic plan according to the Horizon Europe Strategic Plan (2021- 2024) by the European Commission, underscoring the importance of leveraging CPS to meet evolving challenges and opportunities within supply chain management. Interoperability of CPS in their digital supply chain is critical for optimizing operations and ensuring seamless data exchange, enabling efficient coordination and resource utilization throughout the supply chain network. Due to CPS characteristics where heterogeneous components are integrated, achieving seamless interoperability poses significant challenges, including data silos, incompatible protocols, and disparate communication standards. Enriching the modeling of CPS along with the benefits of emerging systems such as AI (Artificial Intelligence) and IoT (Internet of Things) offers a promising avenue to address these challenges. By leveraging advanced modeling techniques and integrating cutting-edge technologies, we aim to develop robust solutions that enhance interoperability of CPS and streamline digital supply chain operations. Simulating interoperability scenarios that include CPS interaction within digital supply chains will provide valuable insights into the effectiveness and scalability of proposed solutions. Through rigorous validation exercises, we will assess the performance, reliability, and scalability of our approach, ensuring its practicality and suitability for real-world deployment.


**Keywords:** Digital supply chain, Interoper
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Development of a1 and fe-based nanophase composites in order to improve mechanical and magnetic properties', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Research objectives and content The aim of this project will be to develop nanophase composites based on two system (Al-Ni-Sn and Fe-Nb-B)obtained by two different process (rapid solidification and mechanical alloying). for two important industrial application of nanoscale materials: mechanical and magnetic properties. The structure and the thermal stability of these alloys produced by melt-spinning and by ball-milling will be investigated by XRD,TEM,DSC and TGA. The technological objective will be to optimise and control the nanostructure to improve hardness and wear resistance (Al-based alloys), and to obtain the best soft magnetic properties (Fe-based alloys). The Fundamental objective will be to understand the behaviour of nanophase composites by a comparative approach to these two systems. Training content (objective, benefit and expected impact) This project is a very good opportunity to investigate the ball-milling method, magnetic materials and magnetic measurements such as TMG and VSM. It will be well suited to improve my knowledge of the possibilities of nanophase composites for industrial applications, building on the experience recently gained in processing these materials. Links with industry / industrial relevance (22) This project is concerned with the development of magnetic and mechanical nanophase composites for application in industry and particulary with Igenierisa Magnetica Aplicada S.L. in Spain and Oxford Instruments in England.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Fuzzy switching strategies for multiple model-based adaptive control' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

Research objectives and content An area of particular industrial interest is the control of complex systems, operating in mulaple environments. In these cases the need for multiple models arises naturally, since a different mathematical model may be needed to represent the behavior of the plant in each environment. I propose the implementation of a fuzzy logic controller for performing the switching and tuning between the available controllers associated to the models. The fuzzy logic controller evaluates the inputs using the fuzzy logic rules and decides which model reflects the current state of the system, and then selects the corresponding controller at each instant. If none of the models is able to provide a satisfactory representation of the current state of the system, the fuzzy switching system may combine, and tune, the output of more than one controller in order to generate the control signal. The approach is extremely useful for single input single output systems, but it is likely to show all its potential in the case of complex multivariable processes, allowing the decomposition of the control problem in manageable subproblems. Thus the proposed research will provide new, alternative methods for studying, analyzing and controlling multivariable systems, which will be integrated in the FAMIMO LTR European Project coordinated by IRIDIA. Expected results of this project include the the development of a novel approach for controller which will enable efficient exploitation of the principle of hybridization, and facilitate simpler, more robust, plant controllers. This will result in a reduction of the complexity of the system allowing the efficient control of a large class of dynamical systems operating in rapidly time-varying environments. Training content (objec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Cerebellar mechanisms for governing goal-directed and social behaviours' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

One of the fundamental goals of neuroscience is to understand how the organization and the dynamics of the neural circuits underly their ability to drive adaptive behaviour. The cerebellar cortex provides a unique system to define such structure-function relationships due to its accessibility, well-defined architecture, and involvement in pervasive brain disorders as autism. Recent evidence suggests that the cerebellum may generate predictions to facilitate a variety of motor and non-motor behaviours, including cognitive processes. The question is how such a diversity of function emerges from such a homogenous structure.   The aim of this project is to characterize the activity of the different cerebellar neurons during a wide range of states to underly their shared and diverging roles in different behavioural paradigms. First, I aim to develop a machine-learning based classifier for identifying cerebellar cell types from Neuropixels recordings. Then, I will use the classifier to characterize the activity of different cerebellar neurons in reward prediction and social interaction tasks. A direct projection from the deep cerebellar nuclei to the ventral tegmental area is believed to modulate both reward circuity and social interaction. However, the cerebellar mechanism underlying these two behaviours is unknown. I will measure and compare the activity of identified classes of cerebellar neurons in these behaviours. Finally, since autism is characterized by having both impaired social behaviour and impaired reward processing, I will also record from autism model mice in the social task. Understanding the computations implemented by the cerebellum in a variety of behavioural states will reveal general principles about how neurons process information and underlie brain func
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Strongly interacting electrons in synthetic superlattices'.

assistant: **Innovation**

Recent experiments on a class of atomically-thin two-dimensional materials, called moiré superlattice systems, have uncovered an entirely new and fascinating world of enigmatic strong-correlation physics and superconductivity. This project will develop theoretical models to explain these intriguing experimental observations. Numerical simulations will play an important role in guiding the theoretical models. An overarching goal is also to explore what lessons we can learn from moiré materials that advance our understanding of other paradigmatic strongly-correlated electron materials such as e.g. the copper-oxide superconductors.The particular objectives of this project are to understand1) the nature of the broken-symmetry orders which appear in different moiré materials,2) the origin of superconductivity observed in carbon-based moiré materials, and the role of the repulsive Coulomb interaction in the electron pairing mechanism,3) whether exotic fractionalized metals are realized in moiré materials, and their potential role in explaining to the ‘pseudo-gap’ regime,4) the Mott insulating ground states of twisted transition-metal dichalcogenides, and the parameter regimes where these correspond to long-range-entangled spin liquids.These objectives address some of the most important and long-standing problems in condensed matter physics, such as e.g. developing a theoretical understanding of electron pairing in the presence of strong repulsive interactions, and the nature of the pseudo-gap phase – which seems to be ubiquitous in strongly-correlated materials. The results obtained in this project will guide future experiments, and enhance the possibility of realizing exotic phases of quantum matter, such as spin liquids, in the lab. The experimental observation of spin liqu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Arthroscopic Regenerative Medicine for Early-Stage Treatment of OA' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Osteoarthritis (OA) affects about 10% of the global population. It has a major impact on a patient’s quality of life; with pain and physical function being worse than chronic obstructive pulmonary disease or even cardiovascular disease. Its prevalence is increasing, by 2020 it will be the 4th leading cause of disability. OA is caused by ‘wear and tear’ and currently only symptoms are treated using pain killers until major surgery is needed, then the joint is replaced. Although joint replacements have improved and often last over 30 years, they do fail with about 10% of all joint replacement operations being to fix a failed implant. In this project JRI is working with University Medical Center Utrecht (UMCU), The Netherlands and the Cell and Gene Therapy Catapult (CGT), UK, to develop a new treatment of OA in the hip and take it to market. This involves catching the disease early when it appears as a distinct lesion. JRI has developed Hummingbird, a system that can get into the complex anatomy of the hip and precisely cut out patches of diseased tissue. Then treating these patches with a cell-based treatment developed by UMCU and successfully used to treat OA in the knee.JRI believes that this treatment can be provided at a competitive price and at a scale to meet the global market. However, to do this they will need to build a robust business case and define in detail the regulatory pathways to the markets in Europe and USA. They will do this by working with CGT.This Feasibility Study is the first phase of this work. With CGT, JRI will define: the regulatory pathway, the cost of providing the treatment, the reimbursement methods and the likely market share. The second phase will be in the first-in-human study and a critical step in both meeting the regulations and defin