RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Non-semisimple differential graded modular functors' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

Non-semisimple differential graded modular functors: While semisimple modular categories can be entirely understood in terms of three-dimensional topological field theory, an equally satisfactory topological understanding of non-semisimple modular categories is not available. The proposed project will solve concrete problems related to the topological understanding of non-semisimple modular categories by unraveling within a homotopy coherent framework the relation between the homological algebra of a modular category (in particular, its Hochschild complex) and low-dimensional topology. The backbone of this approach is the differential graded modular functor associated to any modular category (a consistent system of projective mapping class group representations on chain complexes satisfying excision) that I have recently established in joint work with Schweigert. Among the concrete objectives is a generalization of the Verlinde formula to a statement about two compatible E_2-structures on the differential graded conformal block for the torus. This will naturally link the Verlinde formula to the Deligne conjecture. Moreover, rigidity requirements for categories that can be extracted from a modular functor will be studied systematically using cyclic and modular operads and results of Costello and Giansiracusa. This will lead to a vast generalization of existing string-net techniques, namely string-net complexes for any pivotal Grothendieck-Verdier category in the sense of Boyarchenko-Drinfeld. These string-net complexes can be used to compute differential graded conformal blocks for modular categories which are the Drinfeld center of a spherical pivotal finite tensor category and to create a link to Morrison-Walker blob homology.The key techniques that I will learn during
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Cytoplasmic sensing of Toxoplasma gondii infection and host cell programmed necrosis' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

My goal is to understand how cell-autonomous immunity (CAI) can detect intracellular parasites such as Toxoplasma gondii in their membrane-bounded intracellular niches, how recognition induces necrosis of the host cell, and how host death signalling pathways contribute to inflammatory disorders. Although adaptive immunity ultimately contributes to host survival, the initial response is controlled by innate mechanisms. Mice rely primarily on IFNγ-induced CAI effectors virtually absent in humans, the immunity-related GTPases (IRGs). Parasitophorous vacuole (PV) membrane attack by IRGs results in parasite eviction and elimination, swiftly followed by regulated necrosis of the host cell. Preciously little is known about how parasite sensing drives cell death, particularly in (mouse and human) non-haematopoietic cells (NHCs) lacking the full antimicrobial arsenal of immune cells. Yet necrosis is key to limiting infection and driving parasite chronicity, while potentially eliciting immunopathology. I have 2 objectives: 1) the identification of the intracellular sensor(s) of T. gondii ligands and/or vacuole damage and 2) the dissection of the signalling pathway(s) leading to parasite/cell demise. Using a combination of genetic screens and cell biology tools, I will pinpoint PRR/necrosis genes involved. Elucidating these signalling pathways will help direct therapeutic interventions relevant for toxoplasmosis and inflammatory diseases. This proposal and accompanying career development plan, to be supervised by Prof. Jonathan C. Howard and hosted by the IGC, will be fostered by a dynamic research environment and crucial collaborations that will enable me to receive the necessary training and transferrable skills to establish my own lab. In turn, my extensive training in host-pat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Using Fault-Tolerance techniques to combat Electrical Aspects in deep sub micron IC technology' in the context of a Fifth Framework call.

assistant: **Objectives**

Future IC technology poses challenges to the design community, mainly due to the increased integration density, power supply, and noise and error susceptibility. For the last problem, methods for fault-tolerance are being embedded. These methods are based on known error-correction codes. Initial investigations have now shown that some of the applied codes may have a potentially very advantageous effect on power consumption and noise behaviour. In view of the high benefit/cost ratio, we want to investigate these effects in a structured manner.OBJECTIVESInvestigate a recently discovered non-linear error correction technique on integrated circuit (IC) level. Particular attention will be given to expected associated benefits for chip dimensions, power consumption, simultaneous switching and signal reflections.DESCRIPTION OF WORKOur ambition is to achieve a Fault Tolerance coding/decoding scheme for error correction in integrated circuits, which not only corrects the errors on the chip but is also capable of tackling important issues in bus communication such as power consumption and noise. We will analyse the different electrical issues one by one to finally arrive at a complete insight and a unified approach. First we investigate the benefits of fault-tolerant coding to reduce energy consumption. Next, cross talk-effects will be investigated. Finally the effects on simultaneously switching outputs (ground bounce) will be investigated. For the latter we will focus on memories and microprocessors. This result might be applicable for worldwide standardisation. The University of Bologna is mainly doing the research to combine fault-tolerance and electrical aspects. Philips will perform modelling for the electrical aspects and provide expertise on novel fault tolerant codes. iR
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Soft-Bioelectrochemistry for Artificial Respiratory Chain' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

All cells contain tiny molecular motors made from a large family of proteins including enzymes and antibodies that help the cell produce energy, move, and move material inside the cell. While several biomolecular motors have been identified, the remaining challenges are determining how these species transfer information from one region of a motor to another and how the malfunctioning of these can lead to the development of several diseases. One timely example is the detrimental effect that a disrupted mitochondrial electron transport chain (ETC) can produce in human beings (e.g., cancer, neurodegeneration, heart failure). The SoftBioArt project will explore a new paradigm in ETC by achieving an efficient inter-protein electron transfer at electrified soft-interfaces and to using this platform to pinpoint any weak points for possible electron leakage during the ETC. The SoftBioArt program will result in a new platform bringing biomimetic modified soft-interfaces to a new level, to demystify one of the most relevant living machines within mitochondria (respiratory ETC) where any malfunctioning is linked to the development of several chronic human diseases. Thus, the SofBioArt program will develop model membrane systems that will serve as scaffolds harbouring protein and enzymes of the ETC at soft-interfaces maximizing the electron transfer efficiency at an electrified soft-interface. The SoftBioArt project pushes the boundaries of the current state-of-the-art of bioelectrochemistry at soft-interfaces to determine if this unexplored system can bridge the gap between solid electrode bioelectrochemistry and living systems.


**Keywords:** Bioelectrochemistry, Soft-electrochemistry, Electrochemistry at liquid-liquid interfaces, Electron transport Chain, Membrane proteins, Can
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Bite Ecology from Avian Kinematics and Shape' (BEAKS) targeting Horizon Europe.

assistant: **Abstract**

Bite Ecology from Avian Kinematics and Shape (BEAKS) aims to answer the question, “What factors drive bird beaks to converge in shape and function?” Answering this question will not only deepen our understanding of evolutionary processes, but also provide practical guidance in conserving birds and their key functions in modern ecosystems. BEAKS will combine geometric morphometrics, finite element analysis, and phylogeneBite Ecology from Avian Kinematics and Shape (BEAKS) aims to answer the question, “What factors drive bird beaks to converge inshape and function?” Answering this question will not only deepen our understanding of evolutionary processes, but also provide practical guidance in conserving birds and their key functions in modern ecosystems. BEAKS will combine geometric morphometrics, finite element analysis, and phylogenetic modelling to map patterns of beak form and function evolution and their relationship with aspects like environment, body size, diet, and ectoparasite load. Dr. Miller, the candidate and an expert in avian ecology, and Dr. Marcé-Nogué, the supervisor and an expert in biomechanics, are an ideal pair to head this project and to enrich each other’sknowledge base while doing so. BEAKS will then use these established trends to predict future evolutionary trajectories in response toanthropogenic climate change and identify species whose ecological roles are most likely to be lost without intervention. This type ofmodelling is a specialty of Dr. Püschel, the secondment supervisor, and will be a valuable new skill for the candidate to learn. The hostinstitution, The Universitat Rovira i Virgili, has established connections with educational institutions, news media, and policy makersto ensure the findings of BEAKS are communicated broadly and diss
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Late medieval notions and ideas of work', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The main objective of the project “Late medieval notions and ideas of work” (LABOR OPUS ARS) is to examine historical ideas and concepts of work in the late medieval period and origins of work ethics. The research will concern the 13th-15th century sources, and will make part of social history. However, as it will base in a great extent on analysis of scholastic texts, so it will be related to history of philosophy. The project will continue the previous research of the applicant in the framework of the Marie Curie project, concerning origins of management and enterprise ethics. The research will be focused on examining: a) development of the notion of work and its meaning in the medieval language; b) interconnection between the historical evolution of views on labour and the economic and social changes (taking into consideration long time economic cycles); c) inter-civilisation differences in ideas of labour, especially between Medieval-Latin, Byzantine, and Arabic civilisation; d) influence of ethical appreciation of work on the analytic concept of labour as the source of value and wealth. The research will also include scrutiny in collection of manuscripts and ancient book, with particular emphasis on Central European libraries resources (Cracow, Erfurt, Kórnik, Lublin, Olomouc, Pelplin, Prague, and Wien). The name of the project refers to Latin terms: labor; opus which signifies not only certain output of labour, but was also refers to notion of economic value (opus-indigentia); and ars considered largely as a specialised activity. The project presents first of all historical interest, but also searches into foundations of contemporary concepts of work and work ethics, referring to influence of the idea of work on the economic mentality of society in different civil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Polymeric catalysts and supports: A new paradigm for biomass processing' (POLYCAT), addressing dissemination and exploitation.

assistant: **Impact**

Transforming part of the feedstock base of the chemical industry from fossil feedstocks to biomass, as expected by many researchers and companies, requires fundamental changes in the technologies for processing. While fossil feedstocks are non-polar and processed at high temperatures in the gas phase, most biomass derived feedstocks are polar molecules, which are present in aqueous solution and are typically processed at relatively low temperatures in defunctionalization reactions. Yet, most approaches rely on the conventional wisdom of using catalysts developed for fossil feed processing where the conditions almost always exclude the use of polymeric catalysts. However, for the conditions of biomass processing, adapted polymeric catalysts could be ideally suited. This defines the goals of the proposed research program: known and newly designed polymeric catalysts will be explored with respect to their potential in biomass conversion reactions, which could lead to a new paradigm in catalytic biofeedstock processing. In order to achieve this objective, it will be attempted to produce four selected, exemplary classes of polymers in porous form with adjustable porosity. The porous polymer types will then be post-treated with different methods to introduce catalytic functionality (acid/base and redox functionality). The target processes in biomass conversion are prototypical examples which are representative for whole classes of reactions. These include the depolymerisation of the major components of lignocellulose (cellulose, hemicellulose and lignin) and the targeted synthesis of selected platform molecules starting from glucose as the depolymerisation product of cellulose. Successful completion would provide more efficient access to many novel value chains and establish
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'New Frontiers for Computational Solid Mechanics based on eXtended Level Set representation. Applications to damage mechanics, contact mechanics and stress analysis.""', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The present project intends to introduce new uses of the level set representation of surfaces in order to develop simulation methods able to solve problem currently unsatisfactorily addressed. Three main applications are targeted: localisation phenomena and very complex cracking patterns, precise determination of stresses around contact zones and, finally, introduction in reasonably coarse meshes of the mechanical influence of geometrically small but vitally important reinforcement for the structure safety (weld points,  cables, fillets, …). We plan to address them with a unified technology, parts of which are already being incorporated in codes worldwide because of the contribution of the PI and colleagues in the past ten years.The PI is a specialist in the field of computational mechanics and has been the founder and among the major promoters of the eXtended Finite Element Method (X-FEM), now widely used for crack growth and material interfaces modelling. With the X-FEM, internal or external mechanical boundaries do not need to be explicitly meshed and may conveniently be stored as level sets.The project proposes new algorithm based  an original and extended use of the level set concept in conjunction with the X-FEM :*Thick Level Set (TLS):   We consider that the mechanical variable responsible for the localization of deformation in a softening behaviour (say damage for instance) is not local but tied to the movement of a degradation front located by a level set.*Inequality Level Set (ILS):  We rephrase variational inequality formulation (such as contact) as shape optimization. The shape of the active contact zone is sought and represented by a level set. For any given level set location, a variational equality is solved and a sensitivity analysis is performed to upda
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Puberty onset - influence of environmental and endogenous regulators' (PIONEER).

assistant: **Innovation**

In this STREP we will study the multifaceted interactions between genetic and nutritional factors that may influence sexual maturationThe major objectives of PIONEER are to: 1) obtain updated scientific data on the age of puberty onset in the different regions of Europe.2) identify some genetic and nutritional factors involved in the regulation of the onset of puberty, with special reference to their interactions.3) develop novel experimental test models, including in vivo animal models, optimized for the investigation of genetic and nutritional factors regulating onset of puberty.4)define if specific actions are necessary within EU, to avoid children from maturing too early sexually.The factors that induce early sexual maturation in children are largely unknown. Multiple etiological factors are involved, including both genetic, and environmental and life-style factors, and their complex interactions. Genetic background plays a major role in determining the timing of puberty. Therefore, for understanding role of nutritional factors, it is of paramount importance to know, which individuals have the genetic susceptibility to environmental factors, which may cause early maturation. Clearly, a multidisciplinary approach is required toachieve these objectives. A consortium with a wide range of expertise in clinical and experimental sciences has been established. With regard to the nutritional influences, we will focus on two major questions: i) the impact of nutritional excess and obesity on puberty onset, and ii) the influence of selected endocrine disrupting compounds. Furthermore, we will give emphasis to the development of novel in vivo test models that, because of the complexity of the phenomenon, are clearly needed. With this approach PIONEER will help to identify gene
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Integrated Design of the Components of the Energy System to Plan the Uptake of Renewable Energy Sources: An Open Source Toolbox' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Gathering 22 partners from the EU, Norway, Switzerland and Ukraine, iDesignRES aims to provide public authorities and network operators with open-source toolboxes allowing to plan and to optimise the uptake of low and zero emission energy sources at regional, national and European scales. With these open-source tools, iDesignRES provides latest multi-physics component energy models, comprehensive energy system modelling (in particular assembling of component models), long-term multi-carrier grid planning and optimisation of investment and operation. iDesignRES embraces a new degree of openness, transparency and accessibility to use energy system models and their components. It delivers a harmonized data structure compatible with all modelling approaches (i.e., standardized in a common modelling language). iDesignRES relies on an already built database compliant with these standardized data formats. Based on this modelling and data infrastructure, iDesignRES will develop a unique and innovative cloud-hub platform to run any energy system model online. This will facilitate research collaboration (easier software testing and version control), and increase computational performance (open licenses, cloud services and supercomputing) for average users. To demonstrate and validate the tools, iDesignRES has five real-life cases: two macro region cases (North Sea area and South East Europe), two industrial clusters (Basque and Lombardy regions), and one expansion case in Ukraine. The models and scenario results are combined in the final iDesignRES visualisation tools aimed to inform policy makers and grid operators. The outcome is that the public and relevant authorities can design a renewable energy system entirely online with easily accessible suite of tools, capable to: model