RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'New manufacturing approaches for Hydrogen Electrolysers to provide Reliable AEM technology based solutions while achieving Quality, Circularity, Low LCOH, high Efficiency and Scalability'.

assistant: **Concept**

HERAQCLES stands for New Manufacturing Approaches for Hydrogen Electrolysers To Provide Reliable AEM Technology Based Solutions While Achieving Quality, Circularity, Low LCOH, High Efficiency And Scalability. Project HERAQCLES delivers an operational 25kW electrolyser stack including balance-of-plant based on AEM technology to validate both our novel design-for-manufacturing architecture and innovative components developed for automated production processes.AEM electrolysis offers a more attractive cost/performance ratio compared to state-of-art PEM electrolysis because these is no need to utilise precious group metals in stack components like catalysts, porous transport layers and bipolar plates for generating hydrogen at reasonably high current density. Current stack manufacturing processes face bottlenecks limited by many separate components,  manual assembly and lack of tooling due to low production numbers. The project focusses on increasing Manufacturing Readiness Level from 4 to 5 by collectively advancing all components to comply with automated manufacturing processes at industrial scale: forming of metal plates, 3D-screen printing porous layers, pilot-scale synthesis of membrane polymers and catalyst. Validation occurs in three yearly loops using single cell, short stack and full 25kW stack configurations, where test results are benchmarked against commercially available options to highlight critical improvements of composition, functionality and recyclability.The experienced consortium brings together a unique combination of know-hows acquired in previous projects (e.g. Anione) and manufacturing capabilities provided by strong representation from industrial partners (6 out of 8). If successful, the final qualified stack prototype can be scaled-up quickly.Final
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Environmental Urban Monitoring System' (EnvironmetrY) under Horizon 2020.

assistant: **Objectives**

Environmental monitoring serves a vital industrial and scientific role by revealing long-term trends, leading to new knowledgeand understanding; monitoring is also essential for evaluating environmental planning and policy since without monitoring,they cannot prove their success or identify areas for improvement. Monitoring activities have acquired an increasedrelevance also when considering the Industry 4.0 paradigm. W2W intends to introduce in the market Environ&metrY, as anintegrated, homogeneous, scalable and modular air and environmental monitoring system, for urban and sub-urban areas,deployed through a scalable cloud-based platform for the IoT, developed and owned by the applicant, COIOTE(www.coiote.io), and the new technology for wireless data transmission SigFox, LoRaWAN GPRS as well as NB-IoT or andindoor environments, on the basis of specific users requirements. The innovation is meant to be used in outdoor contexts,but providing also an indoor applicability, since it can be used within close public space environments, such as school,offices, universities, banks, etc. The aim of the project is to develop a complete feasibility study so for: Business strategydefinition and validation; defining market issues; setting technological and organization requirements; developing amultiannual financial overview; defining IPR related issues.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Rituximab in Acute Myocardial Infarction' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Cardiovascular diseases (CVD) represent a major cause of morbidity and mortality. The best current therapy reduces CV risk by only 25-30% and remains ineffective in reducing the excess risk associated with several co-morbidities. Therefore, there is considerable need for new therapies to limit the burden of CVD. Based on a current ERC Starting Grant project, the applicant’s group proposed and validated the concept that mature B lymphocytes are instrumental in the orchestration of the inflammatory response after ischemic myocardial injury, in part through production of CCL7 chemokine and mobilisation/recruitment of inflammatory monocytes to the infarction site (Zouggari Y et al., Nat Med 2013). Our goal now is to translate this ground-breaking discovery and novel therapeutic concept into benefit for patients. The overall objective of the RITA-MI project is to develop a new and cost-effective therapy for patients with acute myocardial infarction (MI) based on selective targeting of the B cell immune response, with the ultimate aim to substantially reduce the high risk of death and major cardiovascular events associated with the disease. Interestingly, the drug, CD20 monoclonal antibody (mAb) rituximab, is readily available for testing in a re-purposing scheme, allowing for rapid initiation of this proof-of-concept clinical trial.Working Hypothesis: A single infusion of rituximab at the acute phase of MI is safe, substantially depletes circulating B cells, and has the potential to limit infarction size and improves myocardial heart function.Overall objective: Does a ‘fire and forget’ approach with rituximab (a single intravenous infusion) reduce infarct size and/or improve heart function in patients with acute STEMI? The overall aim will be pursued through a series of spec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Shakespeare, the Middle East, and Europe' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Shakespeare, through the processes of globalisation, is the only European canonical author who is widely known in the Arab world. He is read in classrooms, occasionally produced on stage, quoted in the press, and alluded to in political speeches. Arab diaspora writers and playwrights have also adapted Shakespeare for performance within Europe and the Arab world. In so doing they confront and explore cultural relationships between East and West in both personal and political contexts. Shakespeare thus provides a common reference point and code of discourse.This study attempts to document and understand the various appropriations of Shakespeare circulating within European diaspora Arab communities and assess their potential for enhancing community relations. It focuses in particular on Suleyman Al-Bayan's groundbreaking reworking of Shakespeare's Hamlet, The Al-Hamlet Summit, which places the work within the context of an unstable Middle Eastern dictatorship wracked by civil war and facing external invasion. Al-Bassan's play, conceived and developed within Europe, proved hugely popular, and controversial, with audiences in Kuwait City, Cairo, London, and Edinburgh. This study examines Al-Bassan's work, and those of other diaspora theatrical practitioners, from the perspectives of both analytic criticism and social analysis. It asks both what such appropriations mean - and whether such appropriations operate to promote social cohesion through the establishment of shared modes of discourse and common cultural understanding.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'European iNitiative for Low cost, Innovative & Green High Thrust ENgine' (ENLIGHTEN).

assistant: **Innovation**

The space sector is a source of economic growth, jobs and exports, participating in all Key Strategic Orientations of the EU strategic plan. Faced with growing competition and technological disruption it is vital to act in support of European space launcher development in order to preserve European independendant access to space. Confronted with smaller market than competitors and lower launch prices, European launchers must improve their competitiveness by halving launch price in the short term. In the long term, Europe will create common building blocks for an integrated and competitive European array of launchers of all scales with reusability functionalities. Europe must thus concentrate efforts on liquid propulsion system which can be half of the launcher cost and is an critical for reusability. In the frame of ENLIGHTEN (European iNitiative for Low cost, Innovative & Green High Thrust Engine), the consortium will strive to increase the competitiveness of european High thrust engine by preparing a demonstrator of Green High Thrust Engine based on Liquid Hydrogen using: • The latest advances in additive manufacturing to reduce the cost and number of engine parts • Edge AI & machine learning algorithm to develop the first space engine Health Monitoring System in Europe necessary to implement reusability • New low cost subsystems in Engine ignition, nozzle extension, valves and integrated flexible linesThis future demonstrator, ENLIGHTEN, will achieve its goal of developing new technologies, would be tested in the frame of a future project in the High Thrust Engine P5 test facilities of DLR. ENLIGHTEN will achieve its goal to lower the cost of launch engines with its consortium mixing aerospace actors like ArianeGroup, AVIO, DLR and ONERA with start ups and SME workin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Enforcement of the environmental regulations on sulphur emissions from ships using drone technology.' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

Explicit I/S is seeking phase 1 funding in order to assess the commercial feasibility of Project Sense ― a drone technology system to monitoring sulphur emissions from ships during cruise.Project Sense is aimed at offering a cost-efficient, highly scalable solution in answer to the urgent demand by enforcement authorities (= customers) for technologies to enforce the international restrictions on ship sulphur emissions in force from 1 January 2015. On this date, the allowed sulphur limits in North European and North American waters will be reduced by 90 % resulting in a dramatic increase in fuel costs for ships operating in these areas. If not effectively enforced, the change threatens to create a devastating competitive disadvantage to those operators - many of them European - who comply with the rules. Creating a difference in market pricing of up to 25-30 % the temptation to keep burning high sulphur fuel will be enormous.But ship emissions are hard to monitor and existing sampling technologies are limited and very costly to deploy. Project Sense solves the enforcement challenge by using smart, self-guided drones programmed to intelligently seek out the ships at sea, sample the plumes using onboard sensors, and transmit the compliance results back in real-time. Based on low-cost hardware components tied together by an advanced software platform proprietary to Explicit I/S, Project Sense presents a highly competitive enforcement alternative to the authorities in Europe and globally.The feasibility study is intended to assess the commercial viability and marketability of the prototype system. In particular: The regulatory requirements needed to operate autonomous drones in the key markets; optimising the software for smart flight and establishing key operational parame
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Detection of Various Cancer Types for Screening and Diagnosis through Blood Samples with Epigenetic Biomarkers Panels' (EPICHECK).

assistant: **Concept**

Nucleix developed a revolutionary platform for the development of Methylation Bio-markers and Bio-Marker panels for screening (early detection of disease) and diagnosis based on epigenetic markers.  The platform identifies changes in specific methylation locations of DNA extracted from body fluids such as – urine, blood, stools and sputum.  A Bio-Markers panel goal is to distinguish between sick and healthy individuals.  The company’s expertise include the identification of the specific loci, comprising a panel of markers that can work in multiplex and generate highly accurate test.  Nucleix technology was proven to be extremely sensitive and specific in its first application. Nucleix focuses initially on the field of cancer detection and screening. Cancer cost the EU €126 billion in 2009, which was 1.07% of EU GDP. 2.45m People in the EU were diagnosed with cancer in 2008, when 1.23 million people in the EU died from cancer in 2008. This is one of the most significant public health issues in the world and in the EU.  Nucleix first product, Bladder EpiCheck is a urine test for the detection of Bladder Cancer. It is aimed for monitoring bladder cancer patients as this is a disease with high recurrence rate and requires tight surveillance. This product will be launched in Q4 of 2015. The test is based on a panel of 15 non-overlapping Methylation markers at loci that were identified, developed and owned by the company.  This product which has better sensitivity and specificity than any other non-invasive test is a proof of the company’s ability to translate its technology to applicable products.   The company plans to develop EPICHECK - diagnostic kits using multi-loci panel of markers, for the detection and screening of lung cancer and colorectal cancer in blood samples –
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Interaction between the exocytotic and endocytotic pathways in polarised cells' (1994-1998) under Fourth Framework.

assistant: **Objectives**

Research objectives and content Through the application of a new electron microcopic procedure, high pressure freezing, we will obtain new detailed information about the structure of polarized MDCK cells. This procedure will give a better represention of the actual situation inside living cells. The combined use of this technique with immuno labelling and tracing procedures, will able us to characterise different types of exocytotic vesicles that pinch of from the trans-Golgi network and that are destined for the basolateral and apical surface of the MDCK cell. With the aid of markers of these vesicles and markers for the endocytotic pathway we will determine whether the exocytotic vesicles intermingle with the endocytotic pathway as they are transported to he surface. Training content (objective, benefit and expected impact) The use of high pressure freezing is a relatively new technique. Since it better represents the situation in living cells, the use and demand for this technique will increase over the next years and will be an important tool for ultrastructural investigations. Techniques from different disciplines such as cell biology, molecular biology and biochemistry will be combined in this project, and such a multidisciplinary approach will be a fruitfull base for research. Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Development of a procedural framework for action plans to reconcile conflicts between the conservation of large vertebrates and the use of biological resources: fisheries and fish-eating vertebrates as a model case' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The objectives of FRAP are: a) the development of a procedural framework for action plans that allow a reconciliation (where conflicts arise) of the conservation of large vertebrates with the use of the same biological resources by humans; b) illustration of the framework using conflicts between the conservation of large fish-eating vertebrates and fisheries as a model. These objectives include an ecological and socio-economic assessment of the positive and negative interactions between fisheries and the conservation of fish-eating vertebrates, the development of efficient ecological and socio-economic mitigation/compensation strategies, and their integration into a framework that allows an effective reconciliation between the vested interests of stakeholders in biodiversity conservation and those in biodiversity use.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Social sensors for secUrity Assessments and Proactive EmeRgencies management' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Social media (SM) statistics during recent disasters (e.g., the 20 million tweets relating to «Sandy» storm and the sharing of related photos in Instagram at a rate of 10/sec) provide tangible evidence that security forces and civil protection agencies could greatly benefit from the effective blending of SM information into their processes. However, despite the widespread use of SM in various domains (e.g., marketing/branding/finance, there is still no easy, structured and effective way to leverage several SM in security/emergency management applications.SUPER is a joint effort of social media experts (incl. social network providers) and security experts (incl. security and civil protection agencies), towards introducing a holistic, integrated and privacy-friendly approach to the use of social media in emergencies and security incidents. The approach will operate at multiple time-scales (before/during/after events), while serving both strategic and tactical level operations. It will be characterized by: a. Intelligent information gathering from SM based on novel algorithms (sentiment analysis, topic tracking, real-time event detection), b. Quantitative assessment of the credibility of SM information towards alleviating manipulation, c. Integrated search over multiple SM towards deriving non-obvious information, d. Gathering/analysis of the citizens’ and the forces’ opinions as part of policy modelling processes, e. Use of SM as an effective way for conveying information to stakeholders, f. Modular integration of the above functionalities within existing processes for strategic planning, management of operations, generation of operational picture and management of policies for emergencies, g. Compliance with privacy laws/regulations. SUPER will be validated in two comple
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'iManageCancer - Empowering patients and strengthening self-management in cancer diseases' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

Chronic cancer treatment places new demands on patients and families to manage their own care. The iManageCancer project will support this challenge and provide a cancer disease self-management platform designed according to the specific needs of patient groups and focusing on the wellbeing of the cancer patient with special emphasis on psycho-emotional evaluation and self-motivated goals. The platform will be centred in a Personal Health Record that will exploit recent advances on Health Avatars for the individual cancer patient surrounded by mHealth applications designed to encourage the patient, enhance clinician-patient communication, maximise compliance to therapy, inform about drug interactions, and contribute to the management of pain and other side-effects of cancer treatment. The Health Avatar PHR will regularly monitor the psycho-emotional status of the patient and will periodically record the everyday life experiences of the cancer patient with respect to the therapy side effects, while different groups of patients and their families will share information through diaries and clinicians are provided with clinical information. The PHR will help assess adherence to therapy, physiological and psychological status while the platform will recommend targeted informative applications and serious games according to the disease type and psycho-emotional status of the patients in order to promote a positive and healthier psycho-emotional state. The disease management platform will be further complemented by an integrated expert system with formal self-management models that will be oriented to decision support, the management of side-effects, adherence to therapy and guidance for patients including drug dose self-adjustments. The iManageCancer platform will be designed