RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Biometric Matching and Authentication System on Card'.

assistant: **Objectives**

The objective of this proposal is to add and integrate biometrics into a standard smartcard for secure and comfortable authentication and identification. Interoperability of the integration will be an important objective in those applications. Biometric smartcard integration will be performed at different levels resulting in a system with higher security and privacy than existing solutions may provide. The proposal will contain all the biometrics and security related mechanisms: Sensor-on-CardWork description:For the realisation of a complete secure biometric smartcard system like Finger_Card we will integrate all the required parts onto a single card:- A one chip silicon fingertip-sensor on the card will act as the biometric sensor.- For integrating this large silicon chip into a smartcard, the adaptation and application of a new thinning technology for large silicon chips shall be used and enhanced.- We will use an advanced, next generation smartcard processor (32Bit) as the kernel because it contains most of the required processing and security features.- Integrated crypto coprocessors allow fast and also secure cryptographic processing of sensitive and critical data. The required biometric algorithms together with the smartcard type security functions will be programmed on the matching processor.The functionality and performance of the developed system will be tested with different applications to get an operational feedback:- e-commerce- health care- access control- data security and encryption.The results of the tests will be collected and published. Special activities will be done for dissemination and distributing the project's information.Milestones:M1: Product and trial definition phaseM2: Pre-test target systemM3-4: Implementation of BioData-on-Card, Matching
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Frontiers in Quantum Technology' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Mission Statement: To deliver an internationally competitive student cohort who will be equipped to be the research and industry leaders of the future through interdisciplinary training at the frontiers of Quantum Technology. The ability to engineer materials at the atomic level has led to the enormously active field of nanotechnology: the analysis, design and fabrication of devices that operate at the leading-edge of optical and electronic technology. This technology has inevitably revealed the true quantum nature of the microscopic world, where particles and waves co-exist and interact in novel exciting ways. The study of quantum information and quantum technology has now been around for some time, and this is the ideal opportunity for the fundamental science to work with industrial researchers to make advancements which the market wants, rather than those which serve only the scientists’ curiosities. Along this line, we have identified two strands of research themes, namely, the generation of extreme light sources and the study of light-matter interactions, with a view to the development of quantum technology. Imperial College has a large team of researchers (17 members of academic staff and 50 postdoctoral fellows: research grants over £30m) working at the leading edge of quantum sciences encompassing surface plasmonics, cold atoms, attosecond lasers and quantum theory. Coupled with newly refurbished postgraduate lecture facilities, a brand new state-of-the-art workshop, and new offices for the quantum theory group this makes Imperial ideal for student training. The associated partners include top academic institutes, government labs and private companies which will be actively involved in student recruitment, research and training. Imperial has been known for attra
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Analysis and Risk Mitigation measures for Induced Seismicity in supercriTICal gEothermal systems'.

assistant: **Objectives**

Combining together carbon capture and storage (CCS) and exploitation of supercritical geothermal systems (SCGS) in volcanic areas, potentially a very large clean energy resource, could open the door to a whole new cutting-edge technology and contribute to the fight against global climate change. CCS-SCGS systems are widely unexplored and constitute a very challenging problem that involves complex coupled processes of multi-phase and multi-component flow in porous media, geomechanics and seismicity. Subsurface fluid injection technologies bear an intrinsic risk of inducing earthquakes by fault re-activation. Predicting injection-induced seismicity is complicated and challenging from a numerical perspective due to the discontinuous nature of faults. ARMISTICE explores for the first time the possibility of safely combining CCS and SCGS technologies by coupling CO2 flow models, developed by the host, to the high-temperature rheology of rock and faults, developed by the ER. Current models of subsurface flow of CO2 and H2O systems are limited to water’s subcritical temperature: in WP1 we address the problem by incorporating the full-range of fluids’ equation of state to determine the optimal conditions for employing CO2 as a geothermal fluid in volcanic areas. We will achieve the objective thanks to the complementary experience of the ER on SCGS and of the host on CCS. Based on the results of flow behavior, in WP2 we will determine the potential for induced seismicity in CCS-SCGS systems and the conditions for safe exploitation. Once again, the decisive advantage to a successful implementation will rely on the complementary nature of the ER past work on fractures and discontinuity modelling, and the one of the host on fluid injection-induced seismicity. ARMISTICE will be stro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Bioprinting with Real-time Imaging and cell-biomaterial Density for Growth Enhancement' (BRIDGE) under Horizon Europe.

assistant: **Objectives**

BRIDGE (Bioprinting with Real-time Imaging and cell-biomaterial Density for Growth Enhancement) wants to elevate 3D bioprinting with an unprecedented microfluidic-assisted approach for developing human skeletal tissue models, addressing gaps in control of the biofabrication deposition process, specifically cell-biomaterial density generation. Human tissues, such as bones, rely on graded cellular arrangements for physiological functions, yet mechanisms like mineralisation remain unclear due to inadequate models. Current 3D bioprinting techniques, typically dispense cells and materials at predefined single densities, but fail to replicate hierarchical, multicellular tissues, significantly hampering clinical advancements.BRIDGE seeks to overcome these limitations by integrating real-time monitoring and tuning of cellular/biomaterial (bioink) density properties during 3D bioprinting. A ground-breaking microfluidic printhead will be engineered to modulate (i) cell density for spatial arrangement control, (ii) biomaterial stirring to guide mineralisation, and (iii) cell-biomaterial imaging for real-time extrusion observation. This system will surpass existing 3D bioprinting technologies by enabling time-resolved imaging and dynamic manipulation of bioinks to prime hierarchical biological processes, such as mineralisation. Advancing the control of bioinks beyond existing approaches, BRIDGE will unveil biological mechanisms in two key studies: (i) the development of a model that recapitulates native mineralisation, cellular differentiation, and vascularisation in skeletal embryogenesis, and (ii) the fabrication of a diseased model to emulate pathological skeletal conditions (e.g., Paget’s disease), serving both regenerative and developmental research. By bridging microfluidics,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Protein structure and function on the genomic scale' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

The research area of the doctoral training concerns the fields of functional and structural genomics, which are the genomic scale enterprises of characterizingthe structural and functional properties of the gene products. The specific projects for the proposed training are:- Development and application of proteomics methods for large scale separation and characterization of proteins involved in specific cellular processes. This involves efficient protocols for measuring CD-IR spectra of separated proteins and the development of novel fold recognition procedures based on a comparative analysis of these spectra;- Developement of theoretical methods for the prediction of protein/gene function. These methods will use state of the art statistical approaches, and will combine sequence information on related proteins and groups of genes, with detailed analysis of available structural information on protein-DNA and protein-protein cognition.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Characterising the interstellar medium of bright, lensed, star-forming galaxies across cosmic time' (COSMICISM), addressing dissemination and exploitation.

assistant: **Impact**

The physical conditions of molecular gas in galaxies, and the impact of star formation and AGN on these conditions and on the emergent stellar IMF, are overarching themes in astrophysics. We are entering an era where numerical simulations of turbulent molecular gas can be informed and constrained by observations of such gas. I propose to investigate, theoretically and observationally, the impact of merger-driven star formation during a vital period in cosmic history, 1 < z < 3, when much of today’s stellar mass was formed. It is here that we must study Larson’s star-formation laws, and turbulence-regulated aspects of star formation, and look for possibly dramatic differences in the initial conditions of star formation, and the different IMF these may impose. These galaxies were significantly more gas-rich and turbulent than local starbursts, with different fragmentation histories and higher star-formation-rate densities (so more cosmic rays). They should yield cleaner signatures of a top-heavy IMF than local starbursts, where periods of ordinary star formation may have diluted such signatures. I will exploit strongly lensed starbursts to study powerful diagnostic rest-frame FIR cooling lines with Herschel's FTS and map velocity fields with JVLA/ALMA, moving beyond studies of integrated galaxy properties to study the activity within starbursts on sub-kpc scales, distinguishing between fueling mechanisms and testing Larson's relations. At this level of sophistication, the analysis of the ISM at z > 1 begins to be comparable to that possible at z ~ 0. Abundances - probed by multi-species, multi-J isotopologues and molecular diagnostics - will reveal the dominant form of nucleosynthesis enriching their ISM, and gravo-turbulent MHD simulations of gas fragmentation in cosmic-
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Catalytic -cyclo - alkylation of aromatic amines', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Research objectives and content To develop a new and clean method for the production of heterocyclic compounds such as piperazines, morpholines and piperidines, that are currently used as building blocks for drugs and agrochemicals. These compounds are produced by the fine-chemical industry using relatively toxic chlorinated intermediates. In addition, a lot of inorganic salts are produced as unwanted side products. The catalytic method to be studied is based on considerably less toxic starting materials and the only side product formed is water. Existing catalysts are ill-defined ruthenium complexes containing monodentate phosphine ligands as well as chloride anions. New well-defined ruthenium catalyst precursors will be synthesed and tested in model N- (cyclo)alkylation reactions of aromatic amines with alkanediols and diethanolamines. A key step in the proposed mechanism is dehydrogenation of alcohols and hydrogenation of imines. Therefore, transferhydrogenation reactions of ketones and imines will also studied. Training content (objective, benefit and expected impact) The host institute has an established tradition of collaboration in a multidisciplinary research environment because of experience in joint projects between academia and industry and frequently hosts students who take part in European exchange programs such as Erasmus and ECTS. It is fully equipped to accommodate post-doctoral as well as graduate students from throughout Europe and to offer them training in research at the forefront of the subject. The candidate will receive research training on a high level in a multi-national research environment that will help him to set-up independent research projects in the area of modern fine-chemicals and materials synthesis. Specific training subjects are the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Framework Architecture Made For Europe - Network' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

FRAME-NET is a thematic network for ITS architecture. It is formed around the European ITS Framework Architecture. It is focused on enhancing the implementation of ITS in Europe, the interoperability of systems and international continuity of services through the use of the Framework Architecture, which is already extending its influence to national and other architecture deployments. The network is centred on dissemination, working groups and clustering activities and will closely co-operate with related activities in Europe. It will give guidance to users and co-ordinate on-going activities involving the Framework. Dissemination includes fora, website, the organisation of workshops including the Eastern European countries. Working Groups will address topics related to the deployment, use and evolution of the Framework Architecture and include validation and impact assessment. A liaison with the USA and Japan will be established. An acceptance group of the member states will be formed for strategic guidance and endorsement. All Member States of the EU can participate, even if they join in later.Objectives:The prime objective of FRAME-NET is to co-ordinate and encourage the wide-scale implementation of ITS in Europe through the deployment of the European ITS Framework Architecture. The aim of this Thematic Network is to provide a focal point for confrontation and co-ordination of ITS architecture-related activities in the whole of Europe. The Framework Architecture was developed by the KAREN project in response to the need for a single reference platform in Europe, which would provide a basis for the development of ITS products and services. A number of national authorities have since started to develop their own national ITS framework architectures, and are adapting KA
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Programming Sensory regulation of Metabolism' (PRiSM) under Horizon 2020.

assistant: **Objectives**

Sensory perception has recently emerged as a master regulator of integrative physiology and behavior, including feeding, by controlling fundamental and pleiotropic regulatory processes of energy and glucose homeostasis. Further, sensory perception is altered in obesity and type 2 diabetes, and childhood obesity correlates with early sensory deficit. Along this line, the discovery of the developmental origins of health and diseases revealed that metabolic diseases have recognized roots in the very early stages of life and can be predisposed to by changes in the perinatal hormonal and nutritional environments, such as occur in cases of maternal obesity and unhealthy diet. In this context, an accumulating body of evidence suggests that maternal health and nutrition could negatively impinge on the development of sensory perception, and subsequently, on the lifelong regulation of sensory-dependent control of metabolic, physiological, and behavioral regulatory processes. This innovative research program consists of four autonomous but complementary projects aimed at (1) deciphering the exact central regulatory processes mediating sensory control of feeding behavior and glucose homeostasis, (2) uncovering the influence of maternal health and nutrition on lifelong sensory regulation of metabolism, and (3) & (4) investigating two independent, yet synergistic, mechanisms that could mediate developmental programming of sensory metabolic regulation. This research program will employ a technology framework of physiological, behavioral, and developmental analyses in mice in concert with state-of-the-art systems neuroscience approaches, including optogenetics, chemogenetics, and in vivo calcium imaging. Collectively, the overarching goals of this research program are to provide new in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Development of a new immunoassay platform based on porous antibody microparticles' (IMPAM), addressing dissemination and exploitation.

assistant: **Impact**

Rapid and sensitive analyte determination in small volumes is one of the main tasks in modern diagnostics for the development of miniaturized in vitro test systems. This is critically important for both health and environmental diagnostics. The traditional approach (ELISA) is a time-consuming multistep process with sensitivity limitations due to usually used planar supports for detection. In this project we intend to develop a new approach for biosensing based on porous antibody microparticles. For this purpose, the combination of a new technique to assemble porous particles at mild conditions (host know-how) and highly sensitive ELISA-based detection system (applicant know-how) will be used. The porous particles will work as a platform with two crucial features: i) specific immunochemical reactions are realized on highly developed particle surface, ii) separation and detection in small volumes (micrometer dimensions). We believe that the proposed approach may open new avenues in future for effective diagnostics.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Allelic Exclusion of Antibody Gene Expression' (2007-2013).

assistant: **Innovation**

Antibody genes in B lymphocytes are assembled from multiple rearranging gene segments, enabling the immune system to protect us from a huge diversity of pathogens. Each B lymphocyte expresses only one antibody specificity on the cell surface (monospecificity), even though there is more than one allele for each antibody chain, a phenomenon termed allelic exclusion. Allelic exclusion requires asynchronous rearrangement of antibody genes combined with feedback inhibition to prevent the assembly of more than one productive allele. This proposal aims to analyze how epigenetic genome modifications influence the asynchronous rearrangements of antibody genes by defining and then altering the precise distribution of histone modifications. Further, to determine the significance of monospecificity to B lymphocyte development and function, this proposal aims to establish a novel gene-targeted mouse that expresses a diverse, but allelically included antibody repertoire. This will provide new insights as to how the immune system reacts specifically against foreign pathogens while maintaining self-tolerance. Hence, this proposal will elucidate the mechanism and importance of allelic exclusion of antibody genes in the immune system. The project will be conducted through a collaboration between the University of Erlangen-Nürnberg, Germany and the University of California, Berkeley, USA. The outcome of this proposal will improve our predictive knowledge of various human diseases including infections, cancer and autoimmune diseases, and thus support sustainable healthcare in the EU.