RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Cloud for Holography and Cross Reality'.

assistant: **Concept**

The impact of technology in the world's panorama is at an all-time high. Advanced media applications enabling immersive communication are becoming ubiquitous in our lives, and there is a global trend to adopt virtual solutions to support day-to-day business operations, social events, and general lifestyle. A subset of these innovative media applications includes Virtual Reality, Augmented Reality, and Holography, but they do not come without their share of challenges and requirements. To enable a satisfactory user experience, the requirements for the computing platform and its underlying network can be considered extreme and far from what can be attainable today. Hence, we propose a Cloud for Holography and Cross Reality (CHARITY), which is a complete framework that attempts to overcome the challenges and meet the requirements of such applications. CHARITY leverages an innovative cloud architecture that exploits edge solutions, a computing and network continuum autonomous orchestration, application-driven interfacing, mechanisms for smart, adaptive and efficient resource management, strong community involvement, and overreaching compatibility with all infrastructure vendors. This integrated framework will be put into test in a broad diversity of use cases targeted at advanced media applications, such as holographic events, virtual reality training, and mixed reality entertainment. CHARITY expects to deliver a working prototype, validated by the most demanding applications, capable of being demonstrated at dissemination events and exploited by a large community of users and companies outside the consortium, paving the way to the mass adoption of more advanced media applications in the market.


**Keywords:** Extremely interactive and bandwidth demanding services, orchest
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Development of BMP2 Neurotrophic Therapy for Parkinson’s Disease' (BMPARK).

assistant: **Innovation**

Parkinson’s Disease (PD) is a progressive neurodegenerative disease. PD affects more than 6 million people worldwide while 1.2 million people have PD in Europe. For the European economy PD has a total socioeconomic cost of €13.9 billion per annum. With the aging demographic the number of individuals affects by PD are projected to double by 2030 highlight the need for disease modifying therapies. The neuropathological hallmarks of PD are the progressive loss of dopaminergic neurons in a region of the brain known as the substantia nigra in the midbrain, and the accumulation of intraneuronal inclusions called Lewy bodies and lewy neurite that consist predominantly of a protein called α-synuclein. Despite over half a century of investigation, there is no disease modifying therapy for PD. I propose that a protein called bone morphogenetic protein (BMP)2 can protect midbrain dopaminergic neurons in the PD brain. BMP2 is distinct from other neurotrophic factors used in the clinical trials to date in that it has a different signalling mechanism that can be targeted to protect dopaminergic neurons. Here I will assess the neuroprotective efficacy of viral vectors carrying the BMP2 transgene in the rat α-synuclein model of PD. I will determine if this molecular therapy can protect dopamine neurons and their axons against α-synuclein induced degeneration to maintain brain dopamine levels and improve motor function. To do this, I will use a multidisciplinary approach which will be paralleled by intensive training and career development opportunities to enable me to make a transformative contribution to knowledge and to achieve professional maturity and independence. In this way, this work has direct relevance for the future development of neurotrophic factors for clinical use in PD
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Evaluating the Climate and Air Quality Impacts of Short-Lived Pollutants', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

ECLIPSE aims to develop and assess effective emission abatement strategies for short-lived climate agents in order to provide sound scientific advice on how to mitigate climate change while improving the quality of air. Current climate policy does not consider a range of short-lived gases and aerosols, and their precursors (including nitrogen oxides, volatile organic compounds, sulphate, and black carbon). These nevertheless make a significant contribution to climate change and directly influence air quality.There are fundamental scientific uncertainties in characterizing both the climate and air quality impacts of short-lived species and many aspects (for example, the regional dependence) are quite distinct to those for the longer-lived climate gases already included in the Kyoto Protocol.ECLIPSE will bring together 11 institutes with established and complementary expertise for a closely co-ordinated 3 year programme. It will build on existing knowledge and use state-of-the-art chemistry and climate models to (i) improve understanding of key atmospheric processes (including the impact of  short-lived species on cloud properties) and characterize existing uncertainties; (ii) evaluate model simulations of short-lived species and their long-range transport using ground-based and satellite observations; (iii) perform case studies on key source and receptor regions (focused on Southeastern Europe, China and the Arctic); (iv) quantify the radiative forcing and climate response due to short-lived species, incorporating the dependence on where the species are emitted; (v) refine the calculation of climate metrics, and develop novel metrics which, for example, consider rate of climate warming and go beyond using global-mean quantities; (vi) clarify possible win-win and trade-of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'From immigrants to colonialists? Italians in Egypt and ""the others"": fragments of subaltern agency in a Colonial sea (1861 - 1911).""' (SubColonialMed), addressing dissemination and exploitation.

assistant: **Impact**

What was the shared experience of global cities in the southern and eastern Mediterranean during the second half of the 19th century? How did the subaltern classes experience the processes of modernization and colonialism? The aim of SubColonialMed is to offer new insights into socio-historical questions regarding the link between migrations and colonialism in the late 19th, early 20th centuries. The project is based on the Italian migration to Egypt but seeks to broaden its analysis to encompass the entire Mediterranean Italian diaspora. It examines the hypothesis that Italian ""colonies"" in the Mediterranean region were pivotal to the foreign and colonial policy of the Kingdom of Italy, contributing significantly to the shaping of national identity. I argue that, even before the occupation of Lybia, the communities in territories subject to the Capitulations legal system served as laboratories for the construction of Italians as national and white political subjects. However, it is a mistake to perceive a direct correlation between metropolitan colonial politics and mass migrations. Operating under the assumption that social transformations arise from global and local processes, this research regards migration as a social-historical phenomenon involving specific and autonomous dynamics of appropriation, hybridization, and rejection. Methodologically, it strives to break new ground by proposing a interdisciplinary study with three components: consular archives, judicial documents, and qualitative biographical data, all used to explore these connections. Combining the micro historical approach with post-colonial theories and intersectional method the project want to test how Italian subalterns in Egypt appropriated nationality becoming colonial actors. The goal is to a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Where the wild things were: how the rise of farming changed human-wildlife relationships' to be submitted under Horizon Europe.

assistant: **Abstract**

WILDERFARM explores the significant changes in human-wildlife relationships that occurred with the rise of farming in western Europe between 6000 and 2000 BCE. Up until now, research on this period has focused strongly on the domestication of animals and plants and the emergence of the new relationship between humans and domesticates. WILDERFARM shifts the perspective, examining how farmers renegotiated the age-old relationship with wild animals and how the rise of farming and its activities, such as livestock grazing and crop husbandry, affected wildlife. WILDERFARM addresses three critical gaps in current research: wild animals are under-represented in archaeological research compared to domestic ones, particularly in research on farming societies; there is still much debate on the nature and timing of the Neolithic transition in western Europe; and in light of the current biodiversity crisis, archaeological perspectives on human-wildlife relationships are valuable but under-utilised.To achieve novel, multi-dimensional insights on the human-wildlife relationship, WILDERFARM integrates methods from zooarchaeology, archaeobotany, biomolecular science, and ecological modelling within a conceptual framework encompassing archaeology, multispecies anthropology, and conservation biology. Three case study areas in western Europe form the basis for a comparative, diachronic exploration of human-wildlife relationships: central Germany, the Netherlands, and southern Scandinavia. Through targeted dissemination and outreach, WILDERFARM seeks to generate an alternative perspective on the emergence of farming, increase awareness of the importance of wild animals in the human past, and offer valuable insights for today’s wildlife conservation education.


**Keywords:** Neolithisation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'FosterinG collaboratIon among primAry producers and beyoNd to promoTe Sustainable growth' (2021-2027) targeting Horizon Europe.

assistant: **Abstract**

The GIANTS project aims to enhance collaboration between primary producers, rural actors, and bio-based industries to accelerate Europe's transition to a sustainable bioeconomy. Through the implementation of a robust multi-actor approach (MAA), the project fosters innovative cooperation models and circular bio-based business practices to maximize the use of agricultural, forestry, and agri-food by-products.GIANTS addresses the pressing need to fully integrate primary producers—such as farmers and foresters—into the bioeconomy, shifting their role from being mere biomass suppliers to becoming pivotal stakeholders within the bio-based value chain. The project will engage over 80 primary producers, bringing them closer to innovative cooperative and circular bio-based business models (CCBBMs). To achieve this, GIANTS will offer the community (i) tailored capacity-building programs designed to create wider value networks, (ii) direct financial support via two Open Calls to support the piloting and scaling-up of new bio-based solutions, and (iii) dedicated decision-making tools, including Impact Shift, a well-established environmental self-assessment tool, and Coompy, a tool developed specifically within the GIANTS framework to address governance aspects of these cooperation models.Access to the comprehensive program developed by GIANTS, along with its integrated support tools, will empower stakeholders to effectively design and implement long-term CCBBMs. These resources, working in synergy, will accelerate the introduction of 30+ new bio-based products to the market, contributing up to 20% reduction in life-cycle impacts and generating over 130 direct jobs while driving more than €44M in annual sales. By reducing reliance on fossil resources, GIANTS will play a crucial role
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'High - redshift galaxies', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

It is difficult to find an Astrophysical problem that has experienced stronger progress in recent years than the studies of Galaxies at High Redshift". The new technological developments and the observations made possible by them, such as the deep observations of the Hubble Deep Fields with the Hubble Space Telescope and the impressive follow-up studies with all the largest telescopes available from the ground (Keck, VLT, VLA, etc.) and from Space (ISO) are responsible of the advance in this field."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Mesoscale organisation of tropical convection' to be submitted under Horizon Europe.

assistant: **Abstract**

Recent research has shown that the spatial organisation of convection (and hence clouds) at the mesoscale (20-200km) dramatically affects the Earth’s energy balance and hydrological cycle. This raises the question as to how the organisation of convection will change with warming, and how it will influence the climate. A poor understanding of the physical drivers of the mesoscale organisation of convection, compounded by an inability to simulate and observe such processes, has hampered our ability to articulate this challenging question, let alone answer it. In MAESTRO I propose to develop observational approaches and analysis frameworks specifically designed to test mechanisms hypothesized to control the mesoscale organisation of both shallow and deep convective clouds. Advances in airborne remote sensing will be exploited to map the spatial structures of clouds and water vapor, to interpret their coupling through the analysis of coherent structures within the clear-air environment around clouds, and to understand their dependence on environmental conditions. This will help understand why and how convective clouds organise at the mesoscale, why the organisation co-varies with water vapor, clouds and radiation locally and remotely, and why it co-varies with climate conditions. By connecting observations from the airborne measurements to satellite observations and meteorological analyses, the generality of the insights from the field measurements will be tested and tempered. Finally, observational insights will be used to assess the new and emerging generation of climate models whose resolution is fine enough to represent the mesoscale organisation of convection and its interaction with climate. MAESTRO will lead to new experimental techniques for studying atmospheric pro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The coordination of dendritic spine morphogenesis and function during synaptic plasticity and pathology' (MORPHINGSYNAPSES) under Seventh Framework.

assistant: **Objectives**

Long-term synaptic plasticity is believed to underlie learning and memory and also the tuning of neural circuitry during development.  Plasticity of excitatory synapses involves both changes in the function and morphology of dendritic spines, small actin-rich, dynamic protrusions that are the sites of excitatory neurotransmission.  The coordination of the structure and function of dendritic spines is essential for proper cognitive function, however the molecular mechanisms that link these processes remain elusive.This project will investigate how the remodelling of excitatory synapses in the brain is controlled by members of the small GTPase family of molecular switches and their regulators, and how these signalling pathways are disrupted in mental disorders.  Specifically, I will investigate the regulation of spine structure and function by Epac2, a newly characterised synaptic guanine-nucleotide exchange factor (GEF) that activates the small GTPase, Rap. Recently identified coding mutations in the EPAC2 gene detected in autistic subjects cause functional impairment of this protein, producing abnormal synaptic phenotypes.  Therefore, elucidating the roles of Epac2 signalling in controlling synapse morphology and function will be essential to our understanding of the potential role of this pathway in this mental disorder.To accomplish this, I have developed an exciting multidisciplinary project focused on the role of Epac2 in spine morphology in vivo and how this impacts on synaptic connectivity and behaviour. I will use state-of-the-art in vivo techniques to examine spine morphology in EPAC2-/- knock-out mice and mice expressing autism-associated Epac2 mutants. I will then decipher the molecular mechanisms that link Epac2 function and shrinkage of dendritic spines to r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'DNA Replication and Biomolecular Recognition' in the context of a Seventh Framework call.

assistant: **Objectives**

DNA replication is at the core of life and strongly appeals to the imagination. It is also a textbook example of template directed synthesis, involving enzyme-assisted molecular recognition of incoming bases by the template strand. Yet, in spite of much effort, many fundamental questions about its mechanism are open. In this research line, using a quantumchemical approach, we aim at two main objectives: (1) understanding the electronic nature of molecular recognition in DNA base pairs, in artificial mimics thereof and in larger, macromolecular aggregates of related systems; (2) unravelling the mechanism of the highly accurate, enzyme-assisted DNA replication and, in particular, understanding the role of hydrogen bonding, steric factors and solvent effects in this multistep process. The two subprojects are intimately connected and reinforce each other. We wish to explore the possibilities of rationally designing monomers whose capability to undergo self-organization can be switched on or off chemically (by a third agent) or physically (by radiation). Potential applications are the controlled and selective formation of macromolecules, nanostructures and materials. Furthermore, a better knowledge and so tuning and control of the DNA replication process is envisaged. On the long term, we hope to contribute to the development in general of quantumchemical approaches to biologically relevant problems, i.e., quantumbiology. Our computations are mostly based on density functional theory (DFT) but also on high-level ab initio theory as well as molecular mechanics (MM). Extensive validation studies, by others and us, have shown that DFT is the method of choice, both in terms of efficiency and accuracy, for large biochemically relevant molecules that involve hydrogen bonding. Our