RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Wild grapevines endophytic microbiome: ecology, epigenetics and application in the biological control of wood pathogens, a synthetic microbiome approach.' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

In recent years, a general decline has been documented in several agriculturally relevant woody plants, and numerousreports point towards a possible role of the plant-associated microbiome. This especially applies to grapevines (Vitis viniferaL.) and to the recent outbreak of grapevine trunk diseases (GTD). This cluster of fungal diseases is considered the greatestchallenge in modern viticulture, due to the complexity of the different pathosystems and the lack of reliable control strategies.During the last >100 years, vineyards have been routinely treated with fungicides, insecticides, herbicides and fertilizers.Recent research have demonstrated that such treatments and other anthropic intervention (e.g., domestication, grafting,training) affect the plant-associated microbiome. These human-driven alterations, exacerbated by grapevines clonalpropagation process, are believed to have led to an imbalance in grapevines endophytic microbiome, which may be a keyexplanation for the recent success of GTD-associated pathogens. The best candidates to investigate the composition of abalanced wood microbiome, unaffected by anthropic activities, are wild populations of V. vinifera subsp. sylvestris (VVS).In this multidisciplinary project, I will join the fields of plant pathology, epigenetics and microbial ecology to (1) unravel the endophyticmicrobiome diversity of wild populations of VVS, using DNA metabarcoding and in vitro isolation techniques; (2) re-introduceendophytes isolated from VVS in cultivated grapevines, by means of a synthetic microbiome transfer; (3) assess the efficacyof the synthetic microbiome in antagonizing GTD-associated pathogens, a next-generation approach to biological control.The outcomes of this project will not only contribute to advance our understanding
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Kondo effect in systems of reduced dimensionality' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Research objectives and content Kondo impurities strongly affect many mesoscopic phenomena. In recent experiments it has been shown that properties of the impurities themselves change in restricted geometries. In this project a theoretical study of the Kondo effect in a disorderd metal of finite size is planned. In the first part of the project, effects of finite system size will be investigated starting from high temperature perturbation theory. In the next step, investigations at low temperatures, i.e. temperatures of the order of the Kondo temperature and below, will be carried out. Of special interest is the situation where typical mesoscopic energy scales, e.g. the Thouless energy, are comparable to the typical energy scale for the magnetic moment, i.e. the Kondo temperature. The objective is to understand a specific model of interacting electrons in a disordered system, and to clarify the relevance of magnetic impurities for mesoscopic phenomena like the persistent current in normal metals. Training content (objective, benefit and expected impact) Within the planned project, I will benefit from the large experience of the Rome group in the theoretical description of mesoscopic systems, disorder, and strongly correlated electrons. My research visit in Prof. Castellani's group will intensify the existing contacts between the Rome and Augsburg group. Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Biogeochemical and physical drivers of deep European margin ecosystems' (BIODEM), addressing dissemination and exploitation.

assistant: **Impact**

Ocean margins are areas of special interest in the field of biogeochemical processes governing exchanges between the continent and the open ocean, and specially those of the carbon cycle. Also, owing to their high biodiversity, ocean margin biota represents an enormous genetic resource, which we are only just beginning to appreciate.The present application, named BIODEM (BIOgeochemical and physical Drivers of deep European Margin ecosystems), aims to understand the biogeochemical (sediment transport, seabed composition, organic matter input) and physical (water column and near-bed current regime) drivers of two margin ecosystems: canyon systems and cold-water coral systems. Canyons are deep incisions of the continental shelf and slope, known as hotspots of bio diversity, major pathways for transportation and burial of organic carbon, and fast-track corridors for material transported from the land to the deep sea. BIODEM will focus on two canyons in the western Mediterranean Sea, the Lacaze-Duthiers and Cap de Creus Canyons (Gulf of Lions).Cold-water corals are suspension feeders, and therefore they are commonly found along bathymetric highs such as seamounts and ridges where currents tend to increase food availability. Even cold-water corals are widely distribute d in the Mediterranean Sea, living cold-water corals are only reported near the Cap de Creus and at the Strait of Gibraltar, and only in the Strait of Gibraltar an active living reef has been observed. BIODEM will focus on these two coral systems in the western Mediterranean Sea. The integrated study of environmental constraints upon which these deep-ocean ecosystems and communities rely will improve the scientific knowledge and will support policy decisions concerning the sustainable management of natural reso
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'A Rydberg-Decorated Atomic Array for the quantum simulation of Gauge theories' (RyDAG) under Horizon Europe.

assistant: **Objectives**

Gauge theories form a cornerstone of modern physics, underpinning the Standard Model of particle interactions and providing effective low-energy descriptions of strongly correlated condensed matter systems, such as spin liquids and high-temperature superconductors. Their broad applicability, particularly in two and three dimensions, makes them a central topic of current research. Yet, analytical approaches are notoriously difficult, and numerical methods remain restricted to low-dimensional systems and short timescales.Quantum simulators, with their high degree of controllability, offer a powerful path to overcome these limitations and explore higher-dimensional gauge theories. Rydberg atom arrays are especially promising: the configurability of optical tweezers combined with the Rydberg blockade can naturally enforce gauge constraints. Yet, on a 2D lattice, realising gauge invariance and magnetic (plaquette) interactions requires (at least) three-body interactions, which remain a significant challenge. RyDAG addresses this by building a strontium-88 Rydberg tweezer platform, which combines a dual approach with the superatom framework developed by our theory collaborators to simulate, for the first time, plaquette dynamics. The project will particularly focus on the study of equilibrium and dynamical properties of a U(1) 2D lattice gauge theory known as the Rokhsar–Kivelson model. Beyond gauge theory simulation, the project will also establish the superatom framework as a versatile toolbox for investigating complex spin systems.


**Keywords:** Quantum Simulation, Rydberg physics, Lattice gauge theory, Spin systems
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Mobile Eukaryotic Chromosomes in Fungal Pathogens'.

assistant: **Innovation**

Horizontal gene transfer (HGT) has significantly shaped the evolution and biology of prokaryotes. In eukaryotes, however, the dynamics, mechanisms and consequences of HGT are less well understood, mostly due to its comparatively low frequency and especially the lack of experimental model systems. Recently, I described a model system for studying eukaryotic HGT, consisting of entomopathogenic fungi of the Metarhizium genus. In this taxon, HGT occurs frequently for entire accessory chromosomes. This massive transfer of genetic material is highly specific, always involving the same chromosome, and is likely regulated by the chromosome itself. Using this unique model system, the MobiChrom project addresses key knowledge gaps of HGT in general and horizontal chromosome transfer specifically: What are the evolutionary dynamics of horizontal chromosome transfer? What are the consequences for the recipient fungus's interaction with the insect host? And what are the mechanisms mediating this specific horizontal transfer? First, I will evaluate the distribution of accessory chromosomes across five co-existing Metarhizium species to understand their transfer frequencies and the involved evolutionary dynamics, while identifying candidate genes involved in HGT or host interactions. Next, I will examine how these acquired accessory chromosomes influence the recipient fungus's interaction with the host, functionally analysing how genes on these mobile chromosomes affect pathogenicity. Finally, I will investigate the genetic mechanisms underlying horizontal transfer, identifying the signals responsible for the specific transfer of the mobile chromosome and the genes that regulate this process. Through these complementary study approaches, the MobiChrom project will advance our understa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Gender for Excellence in Research'.

assistant: **Objectives**

Gender for Excellence in Research (GenderEX) is a three-year project designed to build networks, exchange knowledge and engage best practices to stimulate the integration of the Sex and Gender Dimension in Research Content (SGDRC) in the widening country of Turkey assisted by internationally-leading counterparts in Ireland, Italy, and Sweden. Gender dimension has all too often been overlooked in many scientific areas, sex/gender analysis is an indispensable means to innovate and drive excellence in research and tackle societal challenges. Research that ignores gender interactions is often incomplete and/or biased research, which leads to the formulation of inadequate policies, programs, theories, and outcomes.Gender studies, as a field, is not yet well established in Turkey and a sex and gender dimension is not often integrated into research content. As such for Early Stage Researchers (ESRs) interested in gender studies and gender methodologies, there are few opportunities in Turkey to develop their research skills and capacity.  According to the World Economic Forum’s Global Gender Gap Report (2018), Turkey ranks 130 out of 149 and is in urgent need of advancing gender equality. Researchers’ can play a vital role in identifying the structures and producing solutions that will enhance Turkey's advancement toward gender equality.  The project seeks to build upon and further develop Kadir Has University (KHAS) with its Gender and Women’s Studies Research Center (GWSRC-KHAS) as a site of research excellence in the field of gender research. The overall aim of GenderEX is to further the adoption of SGDRC across multiple scientific disciplines in Turkey and beyond by enhancing the capacity of GWSRC-KHAS for training and engaging more researchers into this field.


**Keywords
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'BEYOND THE CODE: SUSTAINABILITY IN OPEN SOURCE' (BEYOND-CODE).

assistant: **Concept**

Open Source (OS) software is particular in that it can be accessed and modified openly. Originating from technological labs, OS is now ubiquitous and a major part of the EU's economy. Some estimate it to be 450 billions per year (EUR). The increasing ubiquity of OS has turned it into a configuration of social and societal elements such as the decentralised ownership of projects or meeting needs that traditional markets cannot. The socio-technical configurations of OS are not evident, perhaps not even intended. The various meanings of sustainability enact how OS ideas are created and travel beyond their original birthing place, but have, as yet, mainly received a rational/economic focus. This project proposes to explore OS as it travels beyond its designing communities and, in so doing, re-functions the meaning of sociological sustainability that hold it in place. This proposal follows the ER's natural career progression, having studied the development processes of OS projects. In collaboration with the supervisor, the ER has designed a proposal fuses their multi-disciplinary expertise to study sustainability in a new light, along with a tailored training plan that gives the ER key competencies and expertise to secure future career objectives. The CSIC has been chosen as an ideal host for this project, with its large, multi-disciplinary social science department holding some of Spain's most renown OS scholars.Alternative views of sustainability open new research avenues that recognise the importance of other criteria (e.g. inclusive participation), providing novel debate within the academic world. Such articulations will be immediately useful to EU projects that depend on open forms of participation (e.g. EU's CAPS project call), and the EU's agenda on ethical knowledge
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Bimanual Rehabilitation System for Distal Upper Extremity Therapy' (REHAB-DUET).

assistant: **Concept**

Assistance of repetitive and physically involved rehabilitation exercises through use of robotic devices not only helps eliminate the physical burden of movement therapy for the therapists, but also decreases application related costs. Moreover, robot mediated rehabilitation therapy allows quantitative measurements of patient progress and can be used to realize new treatment protocols. In the literature, beneficial effects of robot assisted rehabilitation over conventional therapy have been shown through clinical trials.  In this project, development and testing of a robot assisted rehabilitation system for treatment of upper extremity motor dysfunction secondary to neurological problems is proposed. The project involves a) design and manufacturing of powered exoskeletons to assist  forearm and wrist rotations, b) derivation and implementation of bilateral control techniques, c) synthesis of bilateral and tele-operated control/assistance methods that will allow users to practice self-induced therapy through use of their healthy arms, and d) design of human subject experiments to test efficacy of the developed assistance methodologies.  The primal novelty of the proposed project comes form the system design that allows bilateral and teleoperated assistance schemes. The design is aimed to serve as an investigation and development platform for new treatment and assessment techniques while also being capable of implementing conventional treatments. A self-assisted therapy concept is proposed that has the potential to have a profound and lasting influence the way  rehabilitation therapies are delivered. Targeting the distal parts of upper extremities, the proposed bilateral system is first of its kind in the literature. Moreover, the proposed exoskeleton has a novel parallel
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Prostate cancer: profiling and evaluation of ncRNA' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Annually, over 200 000 new prostate cancer cases are diagnosed in Europe. This number is expected to further increase due to widespread use of prostate specific antigen (PSA) tests on asymptomatic men and an aging population. This leads to high rate of over-detection, where most cases will never experience cancer symptoms during their lifetime. Hence, our current lack of means to predict prostate cancer prognosis will have devastating impact on both life-quality and health care expenditures. Molecular mechanisms of the development of prostate cancer are largely unknown apart from the recognized role of androgens. Lack of knowledge on mechanisms leading to the development and progression of this cancer hampers development of efficacious prevention, specific diagnostics, prognostic, and therapeutic tools. Based on the emerging knowledge on the function of non-coding RNAs (ncRNAs) as regulators of key cellular mechanisms and our own preliminary data on expression of ncRNAs in prostate cancer, it is very likely that ncRNAs are involved in the tumorigenesis and progression of prostate cancer. Our planned studies of ncRNAs can contribute major breakthroughs to optimize individualized prostate cancer treatment by providing both novel biomarkers and drug targets. In this project, we will pursue two major clinical problems: 1) early identification of cases requiring aggressive curative treatment, and 2) develop efficient therapies against hormone-refractory prostate cancer. The project will cover all phases of translational research, from discovery to validation and implementation. We will identify novel ncRNAs, investigate their expression, genetic/epigenetic alterations, and function. We will develop diagnostic tools, identify and validate therapeutic targets. To assure the su
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Hypothesis generation, evaluation and testing: An organic, developmental perspective' in the context of a Seventh Framework call.

assistant: **Objectives**

Hypothesis generation, evaluation and testing are crucial components of many everyday tasks. They are fundamental processes not only for experts, such as clinicians, who are responsible of generating possible hypothesis explaining a cluster of symptoms, prior to evaluate them and finally issue diagnosis. We are continuously asked to generate hypothesis about alternative causes (e.g., ""Why is my baby crying?""), and very likely the composition of this set – sometimes not generated but externally given – critically influence the chosen course of action (e.g., ""Shall I feed him? Is she sick?""). However, hypothesis generation, hypothesis evaluation and hypothesis testing have never been thoroughly analyzed as three building blocks of a same process. In particular, only little attention has been paid to how the initial set of alternative generated/given hypotheses, together with their judged probability, influences the hypothesis testing strategies, in terms of search for information and inquiring strategies. Analyzing this complex process from a developmental perspective will help us disentangling the knowledge and the cognitive components of the process. This insight, together with an attempt to design both a descriptive and a prescriptive model of the organic process from the hypothesis generation phase to the solution, will allow us to develop interventions, especially in education.""