RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Institutions for Knowledge Intensive Development: Economic and Regulatory Aspects in South-East Asian Transition Economies'.

assistant: **Innovation**

The prioritisation and deployment of knowledge within an economy remains a key success factor for long-term economic development, increased productivity and socio-economic sustainability. The achievement of knowledge-driven growth is particularly challenging for emerging market economies that are still seeking to catch up to the frontier knowledge economies. The project seeks to understand the causes and consequences of the differences in the evolution of knowledge intensity of economies, with particular focus on transition countries in South-East Asia. We aim to identify some key micro and macro level institutional incentives for development towards a knowledge economy, and stimuli for capital allocation into knowledge-based investments. Moreover, we seek to study and outline some key channels for efficient regulation that might contribute to knowledge intensification in a transition economy. The project makes use of frontier empirical research methods, including advanced stochastic frontier analysis and dynamic panel data estimation techniques. The conceptual underpinnings of the project are at the intersection of industrial organisation theories, new institutional economics, development economics, and modern concepts in regulatory efficiency and justice. The project will develop lasting excellence oriented cooperation with South-East Asian universities, and contribute to R&D capacity building based on European academic values. Promoting of the project results through intersectoral knowledge transfer will be an important task. We aim to contribute to social innovation through policy suggestions, and to a paradigm shift regarding the role of institutions in transition processes. The project is a joint effort of Swiss and Estonian universities’ economics and law researc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'European alternative splicing network of excellence' (EURASNET) under Sixth Framework.

assistant: **Objectives**

Posttranscriptional events must play a more central role in generating the highly complex proteomes of metazoa than previously believed. This is shown by the large discrepancy between the number of coding sequences of metazoan genomes and the known diversi ty of gene products that they generate. Indeed, alternative pathways for processing the primary transcript of a gene can theoretically generate more transcripts and, ultimately, more protein variants (i.e., isoforms) than the number of classically defined genes in an entire organism. Thus, the process of alternative splicing can greatly expand the information content of genomes. Alternative splicing is an essential component of gene regulation, affecting every aspect of eucaryotic biology, and understanding the mechanisms that lead to alternatively spliced transcripts is essential for the functional interpretation of genomic sequences. In addition, a large number of genetic diseases are caused by defects in the proper processing of primary transcripts, and a lterations in alternative splicing are the basis for multiple human pathologies including cancer, viral infection and inflammatory responses. Despite its prevalence and significance, the molecular mechanisms that regulate alternative splicing are poorly un derstood. The EURASNET consortium employs a wide range of complementary approaches as computational, biochemical, proteomic, genomic, cell and organismal biology to study post-transcriptional gene regulation and its role in disease. The primary purpose of this network will be to develop an integrated approach for the study of alternative splicing that will 1 ) provide durable structures that change the way research in this field is carried out in Europe, 2) establish an innovative and multidisciplinary prog ramm
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'EU-LAC Strategic Partnership for the Implementation of Digital Dialogues in R&I Cooperation' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

SPIDER aims to support the exploitation of the full potential of the newly established BELLA network and the implementation of the outcomes of EU-LAC dialogues in the context of digitalisation and R&I.SPIDER proposes a multi-stakeholder approach to enable the development of an EU-LAC strategic partnership. SPIDER will engage relevant R&I stakeholders from EU and LAC more actively and strategically in supporting dialogues and creating a common and orchestrated vision and strategy for the exploitation of the full potential of BELLA network and the implementation of the outcomes of digital dialogues enhancing EU-LAC cooperation in R&I.SPIDER will adopt a human-centred and participatory approach, combined with an inclusive and intersectional perspective to support the development of strategic partnerships to stimulate the use of digital technologies that can benefit from BELLA and are relevant for EU-LAC R&I cooperation.At the core of this strategy is the EU-LAC Digital Dialogues Implementation Forum (DIF) that is unique of its kind in international cooperation in R&I and will serve as a multi-stakeholder platform to foster dialogues and exchange of best practices to support the implementation of digital dialogues’ commitments. Furthermore, DIF Working Groups will support the adoption of a human-centred approach to technology development, alongside Diversity, Equality and Inclusion (DEI) principles. Coupled with this, SPIDER will assess the use of BELLA and identify pathways for its future exploitation by engaging key actors of the digital ecosystem in project activities. Moreover, SPIDER will implement a Twinning Programme to foster digital partnerships by connecting EU and LAC innovation hubs that can seize the opportunities of BELLA for digital transformation. On top of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Evolutionary genomics of royalty in Messor hybridogenetic ants' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Royalty in social insects is typically environmentally acquired rather than genetically determined. However, this is not the case in an exceptional reproductive system, known as social hybridogenesis. Here, two distinct royal lineages of ants can only produce queens by their own while they need to hybridize to produce workers. Eggs with a pure royal genome are thus genetically fated to become queens while hybrid genomes are fated to become workers. Convergent evolution toward such a baroque reproductive strategy appears common in harvester ant species (four times in Pogonomyrmex and Messor genera), but its origin is still completely mysterious. In this project, I plan to unravel the evolution of this unique system via cutting-edge genomic and molecular approaches.1. Prevalence of social hybridogenesis: I will use genome-wide sequence data to identify novel occurrences of social hybridogenesis across ~500 ant species, in search for potential ecological determinants (e.g. climate or diet) that could favour evolution towards genetic caste determination.2. History of royal lineages: I will use population genomics in three pairs of Messor royal lineages to trace back their evolutionary origin. For this, I will develop a novel ABC method to map introgressions and selective sweeps along royal lineage genomes to detect past hybridization events or fixation of potentially selfish caste-biasing alleles.3. Identifying caste-determining genes: I will use comparative transcriptomics in early ant embryos to identify genes differentially expressed between castes before developmental divergence. Candidate genes will be experimentally validated via i) controlled matings between pure-lineage queens and lab-produced recombinant males and ii) genome editing via the CRISPR-Cas9 technology.I
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'INTEGRITY: empowering students through evidence-based, scaffolded learning of Responsible Conduct in Research (RCR)' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

INTEGRITY’s  innovative approach aims to empower students in responsible research: using RCR INTEGRITY will build a teaching philosophy that underpins comprehensive research integrity training. RCR will incorporate the conventional concerns of FFP (Fraud, Falsification and Plagiarism) and questionable research practices (QRC), yet use a new orientation, namely the empowerment of students. This is vital and innovative because today’s students will encounter dilemmas that current practice cannot yet foresee but need equipment for. INTEGRITY will develop an interactive curriculum with compelling and effective tools that will be co-created with students, using key values, namely Transparency, Honesty and Responsibility. It will include innovative training and mentoring for influencers and will experiment with nudging techniques for effectiveness. INTEGRITY will build capacity in a scaffolded manner, targeting different student group levels, and will deploy training in formal, non-formal and informal contexts and cover the full range of scholarly disciplines, including computer sciences technical studies, social sciences and humanities.


**Keywords:** research integrity,  ethical cultures,  Responsible conduct of research (RCR),  pedagogical innovation,  co-creative design,  scaffolded tools,  mentoring for integrity,  nudging for integrity
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'DIFFUSION OF TOOLS AIMED AT THE SIMULATION OF MOULDING MATERIAL FLOW IN SMES BELONGING TO THE MOULD MAKERS SECTOR IN THE EUROPEAN UNION' (SIM-MOULD) targeting Fourth Framework.

assistant: **Abstract**

The project was concerned with plastic moulding SMEs, i.e. mould-makers and moulders in Europe, and deals with the diffusion of tools aimed at the simulation of moulding material flow. It was implemented by a partnership composed of a leader partner (ASTER - I), three intermediary organisations (ASTER - I, Pole Europeen de Plasturgie - F, ALMI Foretagspartner - SE) and 8 pilot companies (three Italian, three Swedish and two French companies). In addition to the pilot companies, other SMEs also became involved and benefitted from the experience gained through project participation.SMEs in this sector are, in general, experienced in the use of computer systems, mainly oriented to Drafting and Manufacturing. Tools for the computer aided engineering of moulds, able to support the operators in mould design, are available on the market but are not commonly used by SMEs because of cost and application difficulties.By improving the diffusion of such products in SMEs, two important results will be obtained. Firstly, the costs of the software will decrease, and, secondly, the applicability of the software to SMEs will itself be improved, thanks to the broader field experience.The project consisted of the definition of a methodology able to support SMEs from the relevant sectors in their approach to usage of computer aided engineering. The methodology allowed the pilot companies to select the best off-the-shelf mould flow software (this selection was based on the analysis and assessment of the real needs of each company); apply the software and train the employees; test the performances of the selected software integrated with their existing CAD system and in the actual industrial context; compare the obtained results with colleagues in Europe; and customise the software (if appli
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Neuronal Coding of Choice and Action-Selection during Decision-Making in Behaving Mice' (NEUROGOAL), addressing dissemination and exploitation.

assistant: **Impact**

Our daily life is a complex chain of decisions and actions that shapes our behaviors. Individuals tend to choose the best action possible among different alternatives through “goal-directed” decision-making. Given that action-selection is supposed to occur on the basis of the individual subjective evaluation of the relative costs and benefits of each action, two types of information need to be integrated within choice-specific neuronal representations: the causal consequences of an action (outcome) and the value of the outcome. The prefrontal cortex (PFC) appears to be well suited to organize such action-selection. However, despite the growing interest in decision-making over the past few years, the neuronal and synaptic mechanisms underlying goal-directed action-selection in normal and pathological conditions remain elusive. By using two-photon imaging over long-time frames in behaving mice, our project will first determine how alternative choices are encoded by specific neuronal representations in the PFC, and how they are compared during decision-making to select to best action possible. To achieve flexible behaviors in a dynamic environment, individuals must rapidly update these representations according to the difference between the predicted and the obtained outcome. Many cortical and subcortical structures act in coordination to encode and process changes in the outcome value, but the synaptic underpinnings remain unknown. Our proposal will take full advantage of in vivo methods combining electrophysiology, optogenetic and genetically-encoded calcium indicators to address the causal relationship between subcortical population dynamics and prefrontal neuronal processing during decision-making and behavioral flexibility. Finally, given that motivational alterations
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'N2o and ch4 exchange in a temperate coniferous forest in central europe', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

Nitrous oxide (N2O) and methane (CH4) are important greenhouse gases originating from natural and anthropogenic sources. Soils are major natural sources of N2O, but may be both sources and sinks of CH4. My research will add to the current understanding of how different ecosystems in Europe contribute to increasing atmospheric N2O and CH4 concentrations and how carbon and nitrogen dynamics in forest ecosystems interact. I propose to study the magnitude and temporal dynamics of soil-atmosphere fluxes and biosphere-atmosphere gas exchange in a temperate coniferous forest affected by anthropogenic nitrogen deposition in central Germany. I will further develop automated measurement techniques for soil N2O and CH4 fluxes as well as for intra-canopy profiles. I will learn and apply the analyses of stable isotopes in different soil and air compartments as an important part of this proposed fellowship. My measurements will complement ongoing eddy covariance measurements at the EU CarboEurope field site by determining flux origin and partitioning. Data sampled with high temporal resolution enhance the understanding of diurnal and seasonal variation of N2O and CH4 fluxes from forest soils and of the mechanisms controlling ecosystem gas exchange. A process-oriented simulation model will be used to evaluate the carbon-nitrogen interactions in the studied ecosystem and to study effects of nitrogen deposition on soil-atmosphere gas fluxes and ecosystem productivity. The scientific and methodological approach in the proposed project serves as a natural extension of the research I have been involved in during my Ph.D. I will have the opportunity to apply my current scientific knowledge on methane dynamics to a new ecosystem type, to take advantage and to learn new equipment and measurem
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Bottom up biophysics approach to resolve the looping structure of chromosomes' (LoopingDNA), addressing dissemination and exploitation.

assistant: **Impact**

How is DNA spatially organized in our cells? What are the mechanisms that shape chromosomes and how does their 3D architecture direct their function? Recent years have shown that the spatial structure of the genome is of pivotal importance for its biological function. Yet, the basic physics of the formation and regulation of its 3D structure has remained unclear. This proposal aims to understand the fundamental structure of chromosomes using a bottom up biophysics approach, from looping at the single-molecule level to higher levels of complexity.  We focus on so-called SMC protein complexes (SMC = Structural Maintenance of Chromosomes). These ring-shaped proteins are a unique new type of molecular motors that can extrude large loops of DNA that are thought to be the basis of chromosome structure. Our groups recent breakthrough discovery of the looping motor function of condensin SMC paved the way to now answer major open questions, such as the motor mechanism of SMCs; how SMCs handle realistic chromosomal fibers loaded with DNA-binding proteins; how looping relates to gene expression; and whether it is evolutionary conserved from bacteria to man. By answering these questions using single-molecule assays, we will resolve the basic mechanics of the SMC-induced looping of DNA.  We will extend this to even build a chromosome from the bottom up, in a genome-in-a-box approach where we will take genome-length bare DNA and add SMC protein complexes and other DNA-processing proteins. Such a well-controlled bottom-up approach  which to our knowledge is unique  can be expected to generate a radically new understanding of the physical forces and protein systems that shape chromosomes. We are confident that our powerful single-molecule biophysics tools, in collaboration with working
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Nanophotonics to realise molecular-scale technologies'.

assistant: **Innovation**

It is proposed to establish a Network of Excellence in the area of Nanophotonics and Molecular Photonics to address the near- and long term needs of photonic functional components. PHOREMOST builds on the critical mass existing in Europe in this emerging area, rapidly developing as a result of the concomitant progress in nanostructured materials, nanofabrication technologies, nano-scale characterisation techniques, novel concepts linking electromagnetic radiation in electronic and optical systems, recent concepts involving optical properties of non-periodic, fractal and quasi-crystal structures, as well as a better understanding of non-linear properties of molecules. The main driving force behind nanophotonics is the expectation to access the molecular scale dispensing with electrical contacts.PHOREMOST will integrate the activities in the nanophotonics area of 34 pioneering and world- leading partners from universities, research centres and industry to:(a) overcome fragmentation,(b) ensure efficient use of resources,(c) identify future RandD opportunities,(d) guarantee the supply of suitably trained personnel,(e) anticipate future research needs,(f) ensure the excellence in research translates into applications in the life sciences, environment, infotainment and security,(g) benefit from the untapped expertise in accession and third countries and,(h) contribute to the public understanding of science.To achieve its objectives the Network organises its long-lasting impact work, into a synergetic JPA with integrating and spreading excellence activities. Its JPR consists of four strands: gaining functionality by incorporating nanostructures in microsystems, fabricating novel nanostructured materials and functionalising them and, finally, applying this new knowledge to phot