RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Smart Embedded Network of Sensing Entities' under Sixth Framework.

assistant: **Concept**

The SENSE project (Smart Embedded Network of Sensing Entities) will develop methods, tools and a test platform for the design, implementation and operation of smart adaptive wireless networks of embedded sensing components. The network is an ambient intelligent system which adapts to its environment, creates ad-hoc networks of heterogeneous components, and delivers reliable information to its component sensors and the user. The sensors cooperate to build and maintain a coherent global view from local information. Newly added nodes automatically calibrate themselves to the environment, and share knowledge with neighbours. The network is scalable due to local information processing and sharing, and self-organizes based on the physical placement of nodes.A test platform for a civil security monitoring system will be developed as a test application, composed of video cameras and microphones. The test platform will be installed in an airport, to yield real data and performance goals from a realistic test environment. Each sensor is a stand-alone system consisting of multiple embedded components: video system, audio system, central processor, power source and wireless networking. The security application will implement object/scenario recognition (e.g. baggage left unattended, people 'lurking' in an area). Nodes will recognize local objects, using a combination of video and audio information, and neighbouring nodes will exchange information about objects in a self-organizing network. The result is a global overview of current objects and events observed by the network.The key innovative aspects are the methods by which the network perceives its environment, fuses these perceptions using local message passing to achieve local and global object recognition, and calibrates itsel
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'An Integrated Computational and Spectroscopic Investigation of the Enzyme Mechanism of Tryptophan Hydroxylase' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Metalloenzymes play crucial role in neurobiology and therefore they are very important target for drug design for treatment neuropathological processes. In order to make new specific and effective drugs it is crucially important to understand the structure and functions of their drug targets. In this Outgoing Marie Curie Fellowship application we propose combined computational/spectroscopic investigation of the enzyme mechanism of tryptophan hydroxylase – a pterin-dependent non-heme containing iron enzyme in crucial importance for the nervous system. Accurate insight in the mechanism of such a complicated enzyme can not be received using solely computational or experimental methods therefore we will apply integrated combination of state-of-the-art computational methods with most modern spectroscopy methods (e.g. K edge X-ray Absorption Spectroscopy, Magnetic Circular Dichroism and variable-temperature variable-field MCD, and EPR). The results will provide understanding of the structure-functions relationships of this enzyme and will be used in drug design.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'PRe-clinicAl studies of a PSA-based human vaccine candidate targeting visceral, cutaneOus and mucocutaneous Leishmaniasis and Development of the associated procedures for further clinical trials'.

assistant: **Objectives**

The global aim of RAPSODI is : · to develop a human vaccine candidate against most or all Leishmania species that cause the most severe leishmaniasis in the world. An unique vaccinal solution will thus be provided to protect against the various clinical phenotypes (namely visceral, cutaneous and mucocutaneaous leishmaniasis, VL, CL and ML respectively). · to establish all the associated procedures required for the subsequent clinical trials, such as the selection of the appropriate patients and assessment of vaccine efficiency. For that purpose, an international consortium constituted of countries from endemic areas (India, Peru, Tunisia, Spain and France) and embracing multi-disciplinary approaches has been set-up. Based on successful results on VL dogs, the best VL animal model to date, RAPSODI will propose a second generation human-compatible vaccine candidate and confirm its activity in pre-clinical studies. As the chosen antigen is common to most, if not all, Leishmania species, an ambitious universal immunoprotective response is being sought.  RAPSODI will also address the question of population selection in order to ascertain relevant and meaningful clinical trials and vaccination campaigns. Indeed, resistant individuals, when involved in either vaccinated or placebo groups, represent important bias to the analysis of the results. RAPSODI will investigate further the parasitological, immunological and genetic features of such clinical status, and will subsequently apply the generated knowledge to the development of assays and field tests, which represent stand-alone results. The package (vaccine candidate + diagnostic/prognostic tools) proposed by RAPSODI represents a global solution, and as such is believed to have a real impact on the worldwide leishmaniasis pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Europe's Asian Centuries: Trading Eurasia 1600-1830' (TRADE), addressing dissemination and exploitation.

assistant: **Impact**

The project brings global perspectives and interdisciplinary methods to bear on histories of industrialization, consumer and material culture. It investigates the key connector that transformed the early modern world: the long-distance trade between Asia and Europe in material goods and culture. That trade stimulated Europe s consumer and industrial revolutions, re-orientating the Asian trading world to European priorities. The twenty-first century sees a new Asian ascendancy: Europe has lost those manufacturing catalysts of textiles, ceramics and metal goods back to Asia. This project seeks to understand Europe s new challenge of Asia by charting the history of that first global shift between the pre-modern and modern worlds. Europe s pursuit of quality goods in the 17th and 18th Centuries turned a pre-modern encounter with precious and exotic ornaments into a modern globally-organized trade in Asian export ware. But ironically the result was Europe s industrialization and China s and India s displacement as the world s manufacturer. The project compares Europe s trade with India in high quality textiles with its trade with China in porcelain using the records of Europe s East India companies and major museum collections of export-ware objects. The PI will research the English East India Company together with a PhD student, and lead three postdoctoral fellows in comparative case studies on other European companies, especially the Dutch, the French and Scandinavian companies. The research is groundbreaking in bringing the study of traded products, material cultures and consumption into economic and global history, and in making economic history relevant to wider cultural history. It has the vision of a history over a long time period and wide European and Asian comparis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Reliable Medical Grade Home-Based Test for Self-Use for people with Sleep DIsorders' (S-trodes).

assistant: **Concept**

Sleep disorders are prevalent in 1/3 of the global population, across various age groups, and considered a public health epidemic. Nevertheless, sleep disorders are often unrecognized and under-reported. These disorders can contribute to other medical problems, and some may also be symptoms for underlying mental health issues. Sleep monitoring is essential for reliable diagnosis and improved management of sleep disorders. Currently, sleep disorders are only measured during an overnight Polysomnography (PSG); however, this method is limited in clinical implication due its unavailability, high cost, unnatural sleep environment and episodic brain patterns. Smart Skin technology enables monitoring treatment efficacy: the platform is designed to replace PSG with home-based accessible technology. The EIC funding will enable X-trodes to optimize its platform and to perform the clinical validation activities necessary to obtain CE Mark and start commercialization in Europe.


**Keywords:** Parkinson's Disease, Sleep disorders, Brain monitoring, electrodes, printed electrodes, brain waves, sleep monitoring, sleep architecture, wellbeing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The role of intestinal microflora in non-alcoholic fatty liver disease (NAFLD)' (NAFLD) targeting Seventh Framework.

assistant: **Abstract**

As worldwide metabolic disease pandemics rise relentlessly with their concomitant clinical complications such as non alcoholic fatty liver disease, FLORINASH proposes an innovative research concept to address the role of intestinal microfloral activity in the pathogenesis of NAFLD. Firstly, to discover novel metabolic markers for the differential diagnosis and prediction of patient risk. Secondly, to identify HITS as targets for new therapeutic or interventional approaches. The strength of the FLORINASH proposal lies in: i) The construction a large bank of tissues and biofluids (liver biopsies, urine, faeces, plasma) from NAFLD patients that have been phenotyped for obesity and for insulin resistance by hyperinsulinemic clamping. ii) The application of coupled bioinformatic and chemometric modelling of phenotypes via advanced system level omics metrics (utilizing metabolomic, proteomic, transcriptomic, and metagenomic platforms). iii) The mechanistic refinement and validation of human markers and target-HITS in complementary animal models and innovative humanized mice. iv) To validate currently available therapeutic candidates for the target-HITS and synthesize new chemical entities to interfere with these target-HITS. v) To elucidate and widely disseminate the systemic and long range metabolic impacts of intestinal microflora modulation on molecular pathways such as ER stress, lipogenic transcription factors and inflammatory agents. Hence, in addition to fundamental scientific advances that can be tranlated to individual healthcare scenarios, the European community will benefit more widely from numerous social, economical, clinical, scientific impacts resulting from the FLORINASH project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Support for the automation of large scale business processes in evolving environments' (SUPREME).

assistant: **Innovation**

This project will provide software support for large scale business process management. Commercially available process management software (such as workflow) has proven to be very efficient in limited contexts (eg. Insurance claims processing, order fulfillment,...) where it is industrially applied today, but lacks fundamental capabilities to manage very large scale business processes, such as those found in manufacturing and process industries. Computer-supported business process management can potentially have a tremendous impact on the economics of large scale business processes, provided that the supporting software masters the following fundamental aspects:- very large number of ongoing activities (several thousands) that need to be coordinated- processes that are highly dependent, not isolated cases- a large number of application services that need to be accommodated, supported either by commercial software packages or tailor-made applications. - changes in business requirements and underlying IT as a rule, not an exception- processes that span organizational units and need support for distributed process management- processes that accommodate complex multimedia information structuresThe results of the SUPREME project - a comprehensive software platform to automate and manage processes of this kind - will be obtained by bringing together existing complementary technologies for:- process modeling and automation- integration of software packages in the context of distributed systems- multimedia- visualization of large information structuresThe first two technologies are today available in commercial product offerings from two of the industrial partners - offerings that will be extended with results of this project. Multimedia is offered as bundled middleware from pl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Definition of Regulatory Issues for Galileo Organisation' to be submitted under Fifth Framework.

assistant: **Abstract**

The first objective of DERIGOR project is be cope with the urgent need for a suitable expertise on all existing regulation constraint that may impact the establishment of or the way to establish the entire GALLEO programme. It will also answer a new necessary regulatory function at European public level, justifying a long term involvement of the public sector in the management of GALILEO. Based on a regulatory and institutional solution, the third objective of the study is to answer to the urgent need for definition of the contractual and therefore organisational models for GALILEO service provision. The fourth objective of the DERIGOR study is to enhance the proposed solutions for GALILEO regulatory, institutional, legal and financial frameworks by ensuring world-wide IPR and patent survey and analysis as well as defining IPR constraints for the GALILEO system.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'AI-Enabled Connectivity in RIS-Assisted NOMA and RSMA-based Low-Mobility Networks'.

assistant: **Objectives**

The evolution of 6G wireless networks relies on advanced multiple-access technologies that improve efficiency and scalability. Reconfigurable Intelligent Surfaces (RIS) are set to transform 6G by enabling dynamic control of signal propagation channels. This project focuses on optimizing User Equipment (UE) pairings with Resource Blocks (RBs) and RISs in RIS-assisted Non-Orthogonal Multiple Access (NOMA) environments, exploring various configurations to maximize system throughput, fairness, and energy efficiency. By integrating active and passive beamforming, our approach not only enhances communication performance but also reduces the carbon footprint by minimizing the need for additional base stations through efficient frequency reuse. With Munster Technological University (MTU) affiliated with ADAPT Centre, and secondment at Dell Technologies, this research is strategically positioned for high-impact outcomes. The project introduces a novel technique for intelligent role switching in low mobility networks (LMNs), enabling dynamic shifts between near and far users to enhance connectivity time. The methodology incorporates optimization algorithms such as Simulated Annealing, Hill Climbing, Genetic Algorithms, and Random Walk for heuristic solutions. For LMNs, we will develop and evaluate models based on stochastic geometry and deep reinforcement learning (DRL) (asynchronous advantage actor-critic) to optimize the angle of reflection (AoR) for RIS elements. Four-month secondment at Dell, Ireland, is a key aspect where industry-grade validation will assess the performance of RO3 and refine the interplay between the edge-cloud continuum for the DRL. These models aim to address challenges in RIS-assisted networks, supporting seamless 6G connectivity in smart and sustainable
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Genesis and impact of tsunamis on the european coasts : Tsunami warning and observations' (GITEC-TWO).

assistant: **Innovation**

The project GITEC-TWO is a cooperative effort involving partners from seven European countries (France, Italy, Greece, Norway, Portugal, Spain and United Kingdom) and addressing the important problem of predicting, monitoring and managing the risks associated with tsunamis produced directly and/or indirectly by earthquakes affecting the European continent. Tsunamis are known to have affected northern and especially southern European coasts, the European countries most severely threatened being Greece, Italy and the atlantic coasts of the Iberian peninsula. The main consideration is that, in spite of the recognition that Europe is exposed to the attack of disastrous tsunamis, no routinely operating system exists today in the European continent to real-time alert the population and to protect the coasts. This constitutes a serious gap with respect to the Pacific Ocean countries, especially USA, Japan and Russia, that have installed national Tsunami Warning Systems (TWSs) since several decades now and that are cooperating together for a Pacific-wide TWS. GITEC-TWO will be centered on designing and/or implementing local Tsunami Warning Systems in some of the European regions that are the most affected by tsunami activity: this will help reducing the gap with the most advanced countries, will contribute to make new substantial scientific and technical progresses, and most importantly will result in mitigating the the risk for all people living in the areas exposed to the tsunami menace. The GITEC-TWO project, concerning the integration and validation of real-time warning systems for earthquake and tsunamis, is structured in the five following main objectives: 1) Tsunami Warning Systems (TWSs); 2) New Techniques to Model Tsunami Genesis; 3) New Techniques to Model Tsunami Pro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'An innovative and versatile Additive Manufacturing Process: Dynamic Molding' (DM), addressing dissemination and exploitation.

assistant: **Impact**

3D printing technology is marred by various challenges including but not limited to longer production time, restricted design, production wastage and also lack of materials compatible with 3D printing device. 3Deus Dynamics is designed to accelerate innovative technology disrupting the 3D printing process to push the limits of manufacturing by combining the advantages of injection molding and 3D. Our Dynamic Molding technology is a new radical concept of Additive Manufacturing (AM) in which the building environment is composed of a controlled granular phase (powder), behaving like a dynamic molding system in which manufacturing materials (inks) are dispensed. Our technology has successfully produced silicones solutions for medical industry, and personal medical equipment’s. The fund from EIC will be utilized to finalize the development for Silicone, extrapolate to other materials and accelerate the commercial development.


**Keywords:** Injection molding,3D printing,Additive manufacturing process,Dynamic molding