RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'IMaging of Plant Responses to Environmental StresS'.

assistant: **Innovation**

The need to meet the EU’s demand for food and other plant products while preserving natural environments for recreation and conservation of biodiversity in the face of increased population and climatic pressures, has led to an unprecedented demand for an improved understanding of resource capture and utilisation by plants, and of how abiotic stress impacts on plant performance. Imaging techniques are currently being applied in biomedicine to enhance spatial and temporal detection of physiological processes at a range of scales. In plant sciences the potential of imaging techniques in both fundamental and applied research has as yet to be widely exploited. We propose to combine thermal infra-red and chlorophyll fluorescence imaging to investigate the impacts of abiotic stress on photosynthesis and transpiration, at the level of the leaf, plant, and crop. The techniques will be applied to detecting spatial and temporal responses to a range of environmental stresses in photosynthetic reactions and stomatal conductance of leaves of transgenic plants with altered capacity to scavenge reactive oxygen species. Additionally, the techniques will be applied to detection of genotypic variation in rye grass (a model monocot crop) and food crops (wheat, potato) in photosynthetic reactions and stomatal conductance under diverse types, durations, and degrees of environmental stress. Genotypes with different physiological behaviour will be characterised to improve our understanding of stress responses of these crops. Finally, whole crops will be imaged to rapidly determine the impacts of different agronomic practices on carbon dioxide and water fluxes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Ecohydrological interfaces as critical hotspots for transformations of ecosystem exchange fluxes and biogeochemical cycling' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

INTERFACES is a supra-disciplinary training and research network that aims (1) to develop conceptual process understanding of the role of ecohydrological interfaces (i.e. system boundaries) for the transport and transformation of fluxes of heat, energy and water and interlinked biogeochemical cycles (C, N, O) at micro- to landscape-scale; and (2) to create the next generation of supra-disciplinary scientist that are able to work beyond traditional disciplinary boundaries, blend cutting-edge field, laboratory and modelling technologies, and understand the practical relevance of their research.Ecohydrological interfaces connect different environmental (sub-) systems and represent important new cross-disciplinary research domains to extend our knowledge horizons. Moreover, these environmental intersections offer an extremely fertile training ground because exploration of interface process dynamics requires novel linkage between traditionally distinct disciplines, and development of a supra-disciplinary research and training philosophy to foster the evolution of a new generation of scientists.Training and research will span novel distributed sensing technologies, innovative tracer methods and integrated numerical models of heat fluxes, metabolism, biogeochemical turnover and ecological functioning to understand how, when (hot moments) and why ecohydrological interfaces (e.g. aquatic-terrestrial, groundwater-surface water, marine-sediment interfaces) act as critical hotspots for water-dependent environmental processes. The urgently improved mechanistic process understanding developed by INTERFACES will not only provide industries, regulators and decision makers with the capacity to predict the complex, non-linear landscape-wide impacts of ecohydrological interfaces in a chan
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Perivascular cells at the crossroads of inflammation, regeneration and fibrosis' (PERIF) targeting Horizon 2020.

assistant: **Abstract**

The survival of organisms requires the ability to repair tissues upon injury, as well as, after birth, to fight foreign invaders that may have contaminated the wound. This last function is mediated by a complex host response involving immune cells, blood vessels and inflammatory mediators that collectively intend to neutralize the harmful agent and eliminate damaged/necrotic tissue. Initially beneficial, this massive inflammatory response comes with a cost, and adult injured tissues usually heal with a scar, which is an area of fibrous tissue that transiently replaces normal tissue. In chronic settings, scarring can become excessive in a process called fibrosis, to the point of preventing functional recovery of the injured organ and be life threatening. Nearly half of all deaths in industrialized world are due to diseases involving inappropriate, often chronic, inflammatory and fibrotic responses, including lung, kidney and liver diseases, scleroderma, inflammatory bowel diseases, muscular dystrophies, cardiovascular diseases, and tumors. However our current knowledge of the biological processes regulating fibrosis is partial, which has hindered therapeutic advances in the field. Recent data from our team and others drew new attention on a discrete population of mesenchymal cells that wraps around vessels, variously called mural cells, perivascular cells or pericytes, as a major source for profibrotic stromal cells generating scar tissue. Previously known for their vascular protective functions, increasing evidence suggests new and unexpected roles for these cells also in inflammation, repair/regeneration, and cancer. These new findings raise a number of challenging questions relative to their functional diversity, as well as mechanisms of activation/ regulation in dise
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Harnessing the value of tomato genetic resources for now and the future' to be submitted under Horizon 2020.

assistant: **Abstract**

Tomato is a paradigm of crop domestication:  a widely cultivated and consumed vegetable but with reduced genetic diversity and therefore highly vulnerable to emerging diseases and climate change. Fortunately, tomato is rich in genetic resources and information to overcome those difficulties and a coalition of scientists and breeding experts which have generated a large amount of this information have been organized under an effective management structure and a series of objectives to overcome those threats. HARNESSTOM  aims to demonstrate that increasing use of Genetic Resources is key for food safety and security and can lead to innovation and benefit all stakeholders. By capitalizing on the large effort done recently in several EU-funded projects to connect phenotypes/genotypes in a large number of accessions from different germplasm banks and academia, HARNESSTOM will first collect, centralize  and normalize this wealth of information in a way that is easily searchable and displayed in a user-friendly manner adapted to different type of users. Second, HARNESSTOM will develop four prebreeding programs addressing the major challenges of the field: 1) introducing resistances against major emerging diseases, 2) improving tomato tolerance to climate change, 3) improving quality 4) increasing resilience in traditional European tomato by participatory breeding. And additional goal is to increase speed and efficiency in prebreeding what is needed to be able to respond to the emerging challenges in a timely and effective manner. Joint leadership of both academia and industry in each of the WP and the participation of two NGOs  representing different stakeholders guarantees the results of the project will have an impact in industry innovation and also in the society. An effici
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Dietary sources of oxidative stress and their consequences on colon cancer'.

assistant: **Innovation**

Colorectal cancer is a leading cause of cancer in European non-smokers. Dietary changes might reduce the incidence up to 70%, according to epidemiological reports, but the dietary factor initiating them is not known. Researchers in the proposed outgoing organisation have recently found that rats given a diet with reduced thiamin (vitamin B1) for 4 months have small patches in their colons, ACF, that are recognised as precursors to colon cancer (Bruce et al, Cancer Lett. 2003). Furthermore, they have found with studies in tissue culture that the toxic effects of reduced thiamin are markedly worse when the cells are exposed to an oxidative stress (Shangari et al, Biochem. Soc. Trans. 2003).We want to use these preliminary findings as a base to find out whether the combination of reduced thiamin and an oxidative stress from cooked food increases the formation of ACF in the colons of rats at 4 months and whether it will result in colon cancer if extended for a longer period. This will be extended to other natural sources of oxidative stress such as red meat and sucrose. We also want to investigate biochemical measures from blood samples from these animals that can be used as biomarkers of thiamin deficiency and oxidative stress. The final stage would be to correlate biomarkers with the development of colon carcinogenesis in vivo. Our expectation is that these diet changes, reduced thiamin and cooked food, will result in colon cancer in the rat, and that the biochemical measures associated with the development of the tumours can be used to assess this risk in humans.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Using Plasmodium vivax genetic data to estimate the cause of recurrent vivax malaria' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Malaria infects hundreds of millions of people year on year. The WHO is committed to a world ultimately free of malaria. Of the two most important causes of malaria, Plasmodium vivax is the most difficult to eliminate largely because it has the capacity to relapse: causing recurrent malaria via the activation of latent liver-stage parasites. Recurrent malaria can also be caused by the failure to treat a previous blood-stage infection (recrudescence) and, in endemic settings, new infectious mosquito bites (reinfection). Knowing the cause of recurrent malaria is key to understanding malaria epidemiology and to providing efficacious treatment. For example, to evaluate the efficacy of a drug designed to kill P. vivax liver-stage parasites in an endemic setting, reinfections and recrudescence must be separated from relapses. However, there are no direct ways to diagnose the cause of recurrent malaria. To address this problem, I aim to build a tool (Pv3R) that uses Plasmodium vivax genetic data to estimate the probability of Relapse, Recrudescence and Reinfection, and use Pv3R to estimate the burden of relapse and its contribution to transmission, thereby validating Pv3R’s utility. I will achieve my objectives by merging my existing expertise in statistical malaria genetics with the expertise of Dr Michael White and his lab, its ties with field-based P. vivax epidemiology and its capacity to generate P. vivax genetic data. Working with Dr White, I will develop a state-of-the-art statistical inference method to tackle the challenging unsolved problem of differentiating between the causes of recurrent P. vivax. This will generate knowledge that directly improves our understanding of P. vivax epidemiology and, most long-lastingly, a public health resource (Pv3R) that can be used
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Biases in prospective learning and dynamic choice' in the context of a Horizon Europe call.

assistant: **Objectives**

Many important economic decisions are made after individuals have had opportunities to acquire information. For example, investors can do research about the fundamentals of companies to estimate their future stock prices; consumers can read reviews before making purchase decisions; managers can experiment with different organizational structures before settling on one. As information acquisition is costly, decision-makers must evaluate its benefit ex ante by engaging in prospective learning, that is, by trying to predict the amount of information they will receive.PROSPECT aims to investigate experimentally whether individuals are able to correctly assess the benefits of future information acquisition, and to use this information proactively when making dynamic choices. The main objective is to uncover some potential fundamental biases in dynamic decision-making, such as a tendency to acquire too little information and to under-experiment relative to the rational benchmark. In Part 1, I aim to identify biases in prospective learning. The key question is whether individuals are able to correctly forecast the amount of information that a given real-life event reveals. Part 1a will study finance professionals’ ability to prospectively learn from market prices, and Part 1b will investigate whether the general population is able to extract information from past economic events to better predict future economic events.Part 2 studies how individuals take prospective considerations into account when solving dynamic decision problems. In Parts 2a and 2b, I will characterize whether they experiment as much as economic models predict they should, and study two candidate micro-foundations for insufficient experimentation. Part 2c revisits an old idea in behavioral economics, accord
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Speeding collaborations in the life science and health domain of the European research area and beyond' in the context of a Sixth Framework call.

assistant: **Objectives**

The EC currently undertakes most networking through physical meetings (personal, conferences, trade shows etc.). The same is also true for NCPs and IRCs (direct meetings and workshops) and ETI projects, which also facilitate physical networking. Physical networking activities are popular, especially amongst Academia and larger organisations, who normally have the appropriate resources to support these, both in terms of sufficient staff and travel budgets and have a tradition of participation in such activities. However, in the SME world things are quite different, as they have different agendas than Academia (ROI prevails) and often do not have enough resources (both time and money) to perform networking to the desired extent and participate in activities, where academia members attend regularly. It implies that both sides miss out on many collaboration opportunities.The information age has delivered a range of technologies that make effective online collaboration a reality, especially when addressing the needs of SMEs. Broader networking already yields dividends in accelerating the transfer of new technologies from Academia to the SMEs in many aspects and this project aims to effectively leverage stable Internet technologies and methods to take maximum advantage of these tools and approaches, in order to address this strategic objective for the benefit of all parties.SpidERA for LIFE aims at 'bringing together' SMEs and Academia from the life science and health sectors in an innovative, cost effective and highly efficient way. SpidERA for LIFE will utilise the new concept of web-based online networking coupled with social network analysis capability, to facilitate and promote the collaboration between SMEs and Academia with the ultimate objective of improving the healt
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Decolonial Enviromental Justice: from the Middle East and North Africa to North America', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

DEJMENA—Decolonial Environmental Justice: from Middle East and North Africa to North America aims to provide a reading of environmental justice at the crosscut of indigeneity and feminist decoloniality. Drawing on local activists’ and indigenous communities’ struggles with environmental (in)justice, particularly land and water protection, across the Levant (Palestinian farmers in the South of the West Bank), North Africa (Amazigh communities in South-Western Morocco), and North America (Native Americans of the Lacota people in the Midwestern region of the US), this project aims to provide a novel and a much urgent grounding of the locally global impact and value of decolonial feminist environmentalism. DEJ-MENA is—to my knowledge—the first study that combines a decolonial feminist approach to the question of Environmental Justice (EJ) across these multiple locales of indigeneity. By creating a timely comparative understanding of decolonial EJ, DEJMENA will contribute to clarify the way in which evolving global EJ schemes—of which the EU is a major player—are connected to the restoration of indigenous rights in multiple locales. More specifically, it aims to contribute to major areas of EU policy and action (EU Climate action and the European Green New Deal; EU International Action on Climate Change). The ongoing Covid-19 pandemic has proved further the urgent need for more expansive theorising, research and action on EJ with indigenous communities by showing their huge vulnerability,  yet revealing the value of their ecologies. To accomplish this goal, DEJMENA will be undertaken in collaboration with three major academic institutions, Ca’ Foscari University of Venice (UNIVE), Colombia University (CU), and the London School of Economics and Political Science (LSE) and un
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Element-selective impulsive electronic and vibrational spectroscopy of iron-sulfur clusters' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The catalytic activity of metalloproteins and cofactors is at the heart of biological systems’ functioning. Biological reactions occur under physiological conditions in stunning contrast with the extreme temperatures and pressures demanded by industrial processes. The evolutionary “optimal design” of enzymatic reactions led to the ubiquitous presence of key molecular motifs in several metabolic pathways, among which the iron-sulfur (FeS) clusters. Understanding how these multimetallic clusters act in Nature requires mapping their electronic and structural configuration, a challenging task that calls for new investigation methods.In this project, the main issues of conventional spectroscopies for the characterization of FeS clusters are circumvented harnessing the potential of novel atto- and femtosecond sources, implementing element-selective impulsive vibrational spectroscopy (ES-IVS) and element-selective impulsive electronic spectroscopy (ES-IES). The impulsive excitation of FeS clusters with few-cycle pumps in the nearinfrared (for ES-IVS) and visible (for ES-IES) spectral ranges triggers their vibrational and electronic wavepacket dynamics, respectively. Using ultrashort soft X-ray pulses, the clusters’ time-domain response is monitored with element selectivity at the Fe M2,3-edge and S L2,3-edge, retrieving characteristic oscillation frequencies upon Fourier transform of the time traces. ES-IVS will provide direct structural information of FeS clusters measuring Fe and S low-frequency vibrational spectra inaccessible with other approaches. ES-IES will map the Fe electronic states that are at the hearth of FeS catalytic activity and whose experimental observation has proven impractical. This project will establish these techniques as advanced X-ray spectroscopic to