RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Next generation breast and colorectal cancer screening through simple and accurate blood testing.', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Current methods of screening for breast and colorectal cancer are limited in availability and associated with a high cost. For example, mammography equipment for breast cancer screening is particularly limited in Eastern Europe due to the expensive equipment and the required skills that a medical professional must possess. Cologaurd’s and colonoscopy’s for colorectal cancer screening are invasive and painful procedures associated with low patient compliance (50% and 37% respectively). Furthermore blood tests that have been developed to date for cancer screening have failed to demonstrate a high level of accuracy.Todos Medical have developed a simple method for cancer screening known as TBIA (Total Biochemical Infrared Analysis). The CE-marked TBIA platform is unique being the first method using blood tests to show high sensitivity (>90%) and high specificity (>80%). It is a more cost effective and less invasive solution that is more accessible to end user and motivates increased compliance by patients. It is capable of producing results rapidly with the complete process “sample to result” taking less than 4 hours.During phase 1, a feasibility study will be carried out, together with the planning of clinical trials in hospitals that will be performed during the innovation project, to gain the validation and bring the product to the commercialization.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'WeNet - The Internet of US' (WeNet).

assistant: **Innovation**

Diversity permeates our everyday life and covers many dimensions, such as competence, culture, gender or economic across humans and social relations.  Technology has evolved to a point where humans from diverse backgrounds, cultures, and experiences have an unprecedented ability to connect with each other. Yet technology does not in-and-by-itself provide support for developing and maintaining the social relationships that transcend geographical and cultural backgrounds. WeNet addresses this gap by providing a diversity-aware, machine-mediated paradigm of social relations. The goal is connecting people that can support each other, and the key is leveraging their diversity. The WeNet paradigm includes a family of computational diversity-aware models supporting human interaction. Learning models construct diversity profiles based on people's past behaviour and interactions. A diversity-aware search builds upon these profiles to connect the ""right"" people together. To support people’s interactions, a diversity alignment mechanism lifts communication barriers to ensure that messages between humans are interpreted correctly,  and a diversity-aware incentive mechanism generates incentives to motivate people to support each other. The entire paradigm is developed taking into consideration ethical guidelines. The WeNet platform provides the technological infrastructure to set out a series of studies that will be carried within universities worldwide with diverse student populations, and with the final goal of improving students' quality of life inside and outside the academic environment. Beyond universities, WeNet's innovative paradigm impacts human interactions in general, especially those that may benefit from a collaborative approach (creative industries, medical diagnosis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Delineation of a brain circuit regulating energy expenditure to impact body weight' under Horizon 2020.

assistant: **Concept**

Obesity is now a global epidemic with a significant and deleterious impact on human health. My career aim is to clarify the neural underpinnings of energy expenditure (EE) given that this makes a significant contribution to body weight. During my early career, I discovered a circuit linking the ventromedial hypothalamus (VMH) to brown adipose tissue (BAT) and inducing thermogenic beige (browning) white adipose tissue (WAT), regulating EE. Moreover, I found that the VMH-BAT axis is utilized by estrogen (Cell Metabolism, 2014) and nicotine (Diabetes, 2012) to increase EE and decrease body weight. My preliminary data indicate that a critical node between the VMH and BAT is the raphe pallidus (RPa), a brain region known to drive sympathetic tone to BAT. My immediate career aim is to clarify the neurochemical communicator receiving the VMH-EE related input and transmitting to BAT and browning. Given that the RPa is rich in the neurotransmitter 5-hydroxytryptamine (5-HT) which plays a role in thermoregulation, I hypothesize that 5-HT is a crucial component of my circuit. I propose to perform a Marie Sklodowska-Curie Fellowship (MSC) under Prof Lora Heisler’s supervision, arguably the global leader in 5-HT obesity research. Her laboratory is in the Rowett Institute of Nutrition and Health, University of Aberdeen, an Institute with more than a century of focused state-of-the-art obesity and nutrition research. This will supply an optimal environment for a MSC providing me with the opportunity to broaden my research interests, and allowing me to construct an international network of obesity researchers. A MSC will also provide the opportunity for me to be trained in transferable next generation engineered genetic technology that will allow me to rigorously and definitively test
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Gene Therapy of Fanconi Anaemia A' (1994-1998).

assistant: **Innovation**

Objectives:Fanconi anaemia, xeroderma pigmentosum and ataxia telangectasia are all representatives of a group of human genetic disorders characterized by hypersensitivity to DNA-damaging agents and increased propensity to development of malignancy. Haematopoietic failure and proneness to AML are the prime lifethreatening symptoms in Fanconi patients.The only efficient treatment to Fanconi Anaemia (FA) to date is bone marrow transplantation (BMT). Gene Therapy represents an alternative of major interest since in addition to innocuousness, this approach addresses a majority of FA-patients. Addition of a functional FA-gene to haematopoietic stem cells should lead to major improvement of patients' condition. The purpose of this research programme is to provide demonstration of efficient recovery of haematologic anomalies. Knowledge derived from this study making use of a novel vector addressing a disorder of the haematopoietic stem cell with a newly cloned gene, will impact on transfer and expression of a variety of genes into the haematopoietic tissue as well as in a broad range of target cells. This will facilitate the development of gene therapy in a wide variety of disorders.Brief description:The normal FAA gene will be transferred into haematopoietic stem cells of FA-A patients. In vivo selective growth advantage of successfully transduced cells is expected. This is likely to help genetically engineered haematopoietic progenitors settle and reconstitute host without prior myeloablation. The retrovirus vector is a novel Friend virus-derived backbone, which harbours high titers and has been optimized for translation/expression features. It is efficient at transducing CD34+ progenitors with marker genes. Pre-clinical studies are designed in such a way that demonstration o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Surface fluxes in climate system' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

The project focuses on parametrization of the sub-grid scale air-sea/air-land turbulent fluxes of heat, momentum and passive scalars for use in climate, weather forecast and other atmospheric models. The overall goal is to fill the gap between modern knowledge on the physical nature of turbulence and the currently employed flux parametrizations. Speed-up of modern computers has inspired rapidly increasing spatial resolution and accuracy of operational methods. Further progress however is impeded by the lack of flux parametrizations that reflect non-local properties of the planetary boundary layer (PBL) turbulence. The conventional surface-layer similarity theory as well as turbulence closures in operational use are both unable to reproduce non-local transport. As a result the surface fluxes are ill-founded in the conditions of strong convection and strong static stability. The key role in this problem is played by large-scale semi-organized structures, disregarded within the traditional concept of a turbulent flow as composed universally of fully organized (mean) and fully chaotic components. Advanced theoretical concepts of the PBL turbulence together wuth recent evidence from field measurements and numerical simulation studies provide sufficient basis for better understanding and realistic parametrization of the effects of semi-organized structures on the vertical transport. Modern generation of the climate and weather forecasting models provide convenient tools for incorporation and testing of new modules. In the scope of this project we propose application and further extension of the above recent achievements to the revision of traditional formulations and development of improved flux parametrizations in the interests of atmospheric modelling. This work includes :
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Post-war trasistions in gendered perspective: the case of the North-Eastern Adricatic Region' to be submitted under Horizon 2020.

assistant: **Abstract**

The EIRENE project’s purpose is to think afresh 20th-century post-war transitions by taking into account a gendered perspective. Namely, the historiographic consideration of gender thoroughly alters the understanding of social dynamics in multi-ethnic areas during the post-war transitions. They will be observed in the North-Eastern Adriatic region, an overlooked European space, marked by border redefinitions, changes of political systems, and high interethnic conflict intensity, but also by genuine cooperation among ethnic groups. The region has all the qualities of a “laboratory environment” for the study of gender positions and interrelations after World Wars I and II and after the Yugoslav wars in the 1990s. The project will differ substantially from previous attempts to analyse post-war transitions in these aspects: a) longitudinal approach, comparing three post-war periods in order to detect their specifics and (dis)continuities; b) transnational approach, by overcoming nation-centric frameworks of analysis; c) by combining conceptual political and social sciences with historiography; and finally, d) by examining post-war transitions through the prism of gender. Focusing on four research-fields (politics, political violence, work, family), the project will validate innovative analytical concepts of the “inclusion-exclusion paradox” of women in post-war transitions, and women as “cross-boundary mediators”. Within the category of gender, focal attention will be given to women as they are often invisible in historical accounts and remain neglected in historicizing. By aggregating empirical sources, the project will approach the proposed subject matter by investigating the processes of identification across the lines of ethnic origin, class, generations, marital status
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Multi-functional hydrogels for promoting bone fracture healing through local induced release of pharmaceutical agents and gradual matrix replacement by the regenerating bone' to be submitted under Horizon Europe.

assistant: **Abstract**

Bone atrophy and fractures, resulting from trauma, infections, osteoporosis, or cancer, are global health concerns. Standard care with cement and bone grafts has limitations. Synthetic polymers like polymethyl methacrylate risk leakage, spinal issues, and poor healing. Donor shortages for allogenic bone grafting and invasive procedures pose risks such as rejection and viral transmission. HYDROHEAL innovates with hydrogel formulations to address bone strength challenges by treating vertebral and alveolar fractures.HYDROHEAL aims to develop safe, sustainable scaling, and cost-effective formulations using renewable biomaterials for targeted drug delivery, aligning closely with the EU Circular Economy Action Plan and Chemicals Strategy for Sustainability. It is ready to introduce a new era in fracture therapy. The proposed self-solidifying hydrogels release active pharmaceutical ingredients locally upon external stimulation, potentially improving treatment efficacy, preventing infections, and speeding up fracture healing.The objectives of the project are:1. Develop novel injectable hydrogel formulations combining natural substance derivates to enhance healing, inhibit bacterial growth, and monitor therapy progress in vivo.2. Simultaneously manufacture carriers as micro- and nano-particles, surface-functionalized to incorporate pharmaceutical agents, releaseable upon external stimuli for tailored drug release.3. Validate safe and optimized hydrogel formulations for treating vertebral and alveolar bone fractures through in vitro and in vivo tests.4. Demonstrate scalable and sustainable biomaterial manufacturing through safe design methods, machine learning, and predictive life cycle assessment.5. Develop machine learning and hybrid digital modeling methods, combining adaptive
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Advanced nonlinear wave analysis for complex experimental data' (NWACOMPLEX).

assistant: **Innovation**

The proposed research program entitled NWACOMPLEX aims at pioneering studies of nonlinear wave processes in optics and hydrodynamics implementing by young talented theoretical researcher Dr. A Gelash in exceptional collaboration with top-level experimental teams of the EU Host Université de Bourgogne and partners organizations. The transfer of the Fellow knowledge to experimental teams will make his theoretical and numerical developments widely used in practice. The project will strongly enhance the expertise and professionalism of the Dr. Gelash by high-quality trainings, new contacts and collaborations leading to a cascading effect on his career development. The Fellow being experienced inverse scattering transform technique, physics of nonlinear coherent structures and various computational methods proposes novel theoretical approaches and numerical tools for advanced analysis of modern experiments on generation, detection and nonlinear propagation of light in optical systems and waves on the surface of water. The innovative idea of the project is to reveal the nature of complex nonlinear phenomena using inverse scattering transform theory employing the most recent numerical advancements. The project will benefit the nonlinear science by fundamental studies of novel mechanisms of coherent structures interactions, statistic of nonlinear waves, dense soliton and breather gases. The Fellow will present theoretical predictions on nonlinear wave dynamics and statistic which will be verified by experimental groups of the host and partner organizations. The developed numerical tools will allow to generate various nonlinear light and water surface waves patterns for experiments on their propagation, as well as provide the opportunity to reliably analyse complex experimental
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Low particle Emissions and lOw Noise Tyres', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

As car and truck engines have become quieter and cleaner over the past decades, particulate and noise emissions from road-tyre interaction have become the dominant source of traffic-generated particulate emission and traffic noise. Both particulates (airborne or as microplastics) and noise are suspected to contribute to negative health outcomes for those living near busy roads.Currently, non-exhaust particulate emissions are not regulated. Tyre noise is subject to labelling for passenger vehicles, but not yet for trucks. Legislation is in preparation but will require a solid body of evidence of the mechanisms of generation, dispersion and potential health effects of both particulate and noise emissions, in order to introduce measures that are effective and widely accepted.LEON-T will contribute to this body of evidence by investigating both particulate and noise emissions from tyres, and in doing so define and propose practical standardised methods for both lab and road testing—of tyre abrasion rate (mostly larger particles) and airborne particulate emissions. We will also further investigate and model the dispersion and environmental fate of these particulate emissions, as they form a sizeable fraction of microplastics found in the environment.The potential effects of tyre noise on cardiovascular health will be investigated using waking tests and sleep studies. Here we will consider not just average sound pressure level, but also sound qualities such as tonality and timbre—as these can be influenced by tyre and road surface design.The insights gained in these investigations will be used to optimise the design, prototyping and demonstration of a novel airless tyre, which we expect will combine reduced noise, wear and emissions with high safety, reliability and comfort.L
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Creative writing as a tool in second language acquisition', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

This programme will investigate the effectiveness of creative writing as a tool for SLA (second language acquisition) teaching in different cultures and linguistic contexts, using the test cultures of Tunisia and Poland. There are five objectives: to advance current knowledge of effective SLA teaching in different linguistic and cultural contexts; to improve SLA teaching at the Jagiellonian University and the Institut Supérieur des Sciences Humaines de Tunis (ISSHT), enabling curriculum reform in the ISSHT as Tunisia expands its SLA provision, and allowing for greater integration between linguistics and literature in SLA teaching; to raise awareness of creative writing teaching methodology at Strathclyde University; to build the base for future research in SLA by creating a corpus of comparable texts written by Polish learners, Tunisian learners and native speakers; to encourage future cooperation between the partner countries and universities.  The scheme involves visits by experts in SLA from the Jagiellonian and experts in teaching creative writing from Strathclyde to the ISSHT in order to transmit specific methods of creative writing teaching and to allow for cooperation between Tunisian and Polish linguists over standardised creative writing tasks which will be suitable for inclusion in an SLA corpus. The later stages of the scheme involve visits by SLA experts from the ISSHT in Tunis to the Jagiellonian and then to Strathclyde to analyse data and share findings respectively.