RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Personalised In-Silico Cardiology' (PIC) targeting Horizon 2020.

assistant: **Abstract**

Improving healthcare systems mandates a shift towards personalised and preventive management of disease. Specifically, the management of cardiovascular diseases has a huge impact on European society in terms of mortality, morbidity and healthcare costs, being responsible for 1.9 million deaths in the EU annually (42% of all deaths) with a total cost of €169 billion.Advances in computational and simulation technologies now provide us with unparalleled capacity to analyse clinical data in-silico, rendering the vision of an early detection of disease through model-based diagnostic biomarkers, and the design of personalised therapies through predictive models. In-silico methodologies enable the optimization of clinical protocols, from data acquisition to device parameters and intervention choices. In-silico tools also enable the reduction of animal use in the development of novel cardiac therapies and drugs. PIC is the European ITN that will train the cohort of 15 of the future innovation leaders able to articulate and materialise the vision of a Personalised In-silico Cardiology (PIC). It will address specific challenges originated by cultural and structural barriers between sectors and disciplines, articulating a fluent dialogue and work between clinicians and engineers. Fellows will be exposed to the generation of novel academic ideas, the design of practical solutions that meet actual clinical needs, the translation into industrial products, and the compliance with safety and regulation requirements. This will be achieved by pooling the expertise of leading experts from 4 academic, 3 industrial and 3 clinical beneficiaries. A highly inter-disciplinary program will be delivered in 4 research work packages, with companies leading two of them. New talent and innovation wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Science, Etchics and Technological Responsibility in Developing and Emerging Countries' (SET-DEV).

assistant: **Concept**

The project general aim is to support the research systems of two countries, India (an emerging economy/EE) and Kenya (a Developing Country/DC), by assisting them in developing their own research ethics perspective within the context of an initiative in favour of research activity and in the sharing of responsibility on scientific and technological research (STR). The promoters intend to contribute to achieving the objective of developing actions of capacity building in DC and EE, by means of an international dialogue, in the field of ethics and science. The specific objectives to be achieved through initiatives of coordination, capacity building, training and awareness raising, are: to strengthen the levels of information and awareness on ethical issues connected with ST by fostering a dialogue among scientists from different parts of the planet; to integrate ethical issues to the wider issue of enhancing the socialisation of research (this notion refers to the dynamics and processes of a social nature that are incorporated in scientific and technological research.), in view of the strengthening of local research systems (with particular attention to the factors that can facilitate or hinder the development of STR systems; to activate processes of building institutional capacities and skills on these themes; to develop ethical guidelines and standards that refer to international instruments and codes on ethics but which are also sensitive to and compatible with the local values, STR levels and needs; to define perspectives of socialisation of science and technology that take into consideration local needs and are in compliance with EU standards in ethics. The project will have an overall duration of 36 months and include 12 WP.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'HINDERING DENDRITE GROWTH IN LITHIUM METAL BATTERIES' (HIDDEN), addressing dissemination and exploitation.

assistant: **Impact**

The HIDDEN project develops self-healing processes to enhance the lifetime and to increase the energy density of Li-metal batteries 50 % above the current level achievable with current Li-ion batteries. The HIDDEN consortium develops materials and their processes to functional battery layers as scalable, industry compatible, manufacturing technologies enabling sustainable energy storage technology with longer battery lifetime and higher energy storage capacity for more efficient utilization of sustainable, carbon free energy production technologies. HIDDEN will develop novel self-healing thermotropic liquid crystalline electrolytes and piezoelectric separator technologies, investigate both technologies with protective additives, and apply multiscale modelling means for electrolyte design and analysis algorithm to monitor the dendrite growth. Technologies will be upscaled from laboratory to industrial manufacturing processes, tested and finally demonstrated by assembling battery cells with battery layers and the temperature control system.  The project brings together a strong interdisciplinary consortium of seven partners, industry and research balanced, with state-of-the-art background in battery chemistry and physics, materials modelling and analysis, upscaling of novel technologies by printing and coating, as well as in industrial assembling of battery cells. This is complemented by external advisory board with representation of key industry end-users.


**Keywords:** Lithium metal battery, self-healing, dendrite, liquid crystal, machine learning, piezoelectric separator
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'E2E-aware Optimizations and advancements for the Network Edge of 5G New Radio', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

ONE5G commits to provide technical investigations and recommendations to evolve ‘5G’ towards ‘5G advanced’ as requested by the work program. Release 15 from 3GPP is about to set up a valuable initial specification for paving the way to reach the ultimate goals for 5G. However, we see major aspects not yet reasonably covered, requiring more research activities to happen: - Means ensuring 5G to be consistently rolled-out not only in agglomerations, but also in less densely populated areas, to  avoid the digital divide to occur as in earlier generations.- Means ensuring 5G to support all foreseen services efficiently and concurrently in a generic way, to avoid the emergence of a set of specialised solutions lacking synergy effects such as economy of scale and multiplexing gains.- Means ensuring 5G to efficiently handle all degrees of heterogeneity stemming from the multiplicity of services and environments, network nodes and devices, spectrum bands and access types (licensed, unlicensed and lightly licensed).In ONE5G, 14 experienced European players of wireless research are gathering to jointly drive forward the vision of 5G by - delivering advanced link enhancements beyond Release 15, including efficient multi-service access schemes, advanced massive MIMO enablers and link management mechanisms- researching and proposing highly generic performance optimization schemes for 5G, to achieve successful deployment and operation, including optimizations for both the network operator and the E2E user-experienced performance- identifying the cost driving elements for the roll-out and operation and to propose adaptations to allow sustainable provision of wireless services everywhere- validating the developed extensions and modifications through different approaches: analytically, b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'InnovaTivE in situ 4D biopriNTing for regenerAtion of CoLorEctal mucosa and submucosa' (TENTACLE) under Horizon Europe.

assistant: **Objectives**

Colorectal diseases are a cohort of pathologies that affect the mucosa and submucosa layers of the anus, rectum, and colon of more than 2 million individual in the EU. Among them, familiar adenomatous polyposis (FAP) and ulcerative colitis (UC) seriously compromise the patients’ quality of life. These pathologies could benefit from the removal of the intestinal mucosa and submucosa, however no strategies exist nowadays for their replacement. Then, when their removal is necessary, the patients undergo a proctocolectomy (i.e., surgical removal of the rectum and all or part of the colon) with a subsequent ileal pouch. Although preserving the patient's continence, the procedure is burdened by significant complications.In this scenario, TENTACLE pioneers a radically new strategy for the surgical treatment of UC and FAP, providing an innovative in situ 4D bioprinting strategy, for the regeneration of colorectal mucosa and submucosa. The TENTACLE in situ 4D bioprinting suite include: i) a colonoscopic bioprinter, featuring an extrusion-based bioprinting unit, an valvejet printhead, a mesh delivery system and a photocrosslinking device; ii) in silico tools for personalizing the bioprinting procedure; iii) two novel bespoken bioink formulations containing patients’ cells, including suitable functionalization strategies. The mucosal formulation will feature a 4D shape morphing behavior to recreate the colorectal mucosal crypts. Within TENTACLE, the entire procedure will be validated ex vivo and in vivo, thus paving the way for translating the bioprinting suite toward the clinics, by: i) identifying a GMP-compliant cell expansion protocol, ii) scaling up of the manufacturing routes, iii) promoting involvement and acceptance of surgeons and patients, iv) aligning with the EU regula
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'X-Chromosome Inactivation and Plasticity in pre-implantation mouse embryo'.

assistant: **Innovation**

In mammals, one of the two X chromosomes is inactivated in females to enable dosage compensation for X-linked gene products. In mice, the first changes associated with X-inactivation occur during early pre-implantation embryogenesis. At the morula-blastocyst transition, paternal and maternal X chromosomes are differentially reprogrammed in the three cell lineages constitutive of the late blastocyst. In order to characterise the factors and epigenetic marks involved in this reprogramming process, we propose to compare the X chromatin structures in model cell lines derived from blastocysts where the paternal and maternal X chromosomes can be distinguished. To do this, we will analyse chromatin modifications and chromatin compaction using a polymorphic tiling array covering 3,5Mb around the X-inactivation centre – a genomic region on the X chromosome controlling initiation of X-inactivation. We will also study the nuclear organisation of the two X chromosomes using three-dimensional Fluorescence In Situ Hybridisation (3D FISH) techniques. These experiments will be repeated in pre-implantation embryos per se. This project addresses important early developmental decisions in mammalian embryology and should help to characterise the molecular principles involved in epigenetic reprogramming and genome plasticity during early embryogenesis.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'COMBINED USE OF HOT DEEP-WATER AT THE COCATION OF BLUMEAU/STEIERMARK-AT' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

The primary aim of the project is the reduction of the ejection of pollutants and protect of the environment. This reduction of pollutant ejections should be achieved by the substitution of the existing oil heating plant and because the municipality of Blumau wants to supply several buildings with geothermal heat also.Besides a great amount of the current-consumption of the hotel and the thermal spa should be met by the own generation of current planed in this project. The energy coming from the temperature of the thermal water on the lowest level should be used for agriculture applications.Especially in this region with structural problems the use of renewable energies with its great public acceptance shall be the basic for the creation of a lasting tourism industry.By the combined use of this thermal water with a lot of gas in it which is similar to the hot ground water you find in the south of europe the dissemination of this technology in other countries of the EU should be realized.In general the economic and social cohesion of the European Community should be strengthened by participation of several companies from different countries in the project.The first and main important estimated result of this project is the reduction of the ejection of pollutants (CO2 , SO2 and NOx) because of the substitution of fossil fuels.This installation should demonstrate a non-polluting method of power generation with the help of another renewable energy which could be used in addition to solar energy. By using this special kind of deep water in a geothermal plant a possibility of multiple using of heat water which normally only exist in the southern part of Europe can be shown.For the region of Blumau it is a very important chance that with the help of this project the structure
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Morphological Impacts and COastal Risks induced by Extreme storm events'.

assistant: **Innovation**

The project is specifically targeted to contribute to the development of a probabilistic mapping of the morphological impact of marine storms and to the production of early warning and information systems to support long-term disaster reduction.  A review of historical storms that had a significant impact on a representative number of sensitive European sites will be undertaken. The nine sites are selected according to wave exposure, tidal regime and socio-economical pressures. They include outmost regions of the European Union at the border with surrounding states (e.g. the area of the Gibraltar Strait, the Baltic and Black Sea).  All data will be compiled into in a homogeneous database of occurrence and related socio-economic damages, including the following information on the characteristics of the storms, on their morphological impacts, on the damages caused on society, on the Civil Protection schemes implemented after the events.  Monitoring of selected sites will take place for a period of one year to collect new data sets of bathymetry and topography using state-of-the-arts technology (Lidar, ARGUS, Radar, DGPS). The impact of the storms on living and non-living resources will be done using low-cost portable GIS methods.   Numerical models of storm-induced morphological changes will be tested and developed, using both commercial packages and developing a new open-source morphological model. The models will be linked to wave and surge forecasting models to set-up a real-time warning system and to implement its usage within Civil Protection agencies. The most important product of the project will be the conception of Storm Impact Indicators (SIIs) with defined threshold for the identification of major morphological changes and flooding associated risks. Finally, th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Genomic fine-mapping of malaria susceptibility loci', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

Malaria due to Plasmodium falciparum kills over a million African children each year. We need to get a better understanding of natural mechanisms of host defence against the parasite, to help in the search for better ways of treating severe malaria and for an effective malaria vaccine. This proposal aims to understand the association between severe malaria and polymorphisms of TNF, the gene encoding tumour necrosis factor. Several different associations have been observed between TNF and severe malaria, but it has not yet been conclusively shown that that the causative polymorphisms are in TNF itself, as opposed to neighbouring genes that are in linkage disequilibrium. The genomic region where TNF is located contains a rich variety of immune genes as well as several poorly understood genes that are suspected to have animmunological function. My goal is to carry out genomic fine-mapping of the region of the human genome around TNF, to determine the causal basis of associations between TNF polymorphisms and susceptibility to severe malaria in African children. I will address two fundamental questions: (1) Considering a total of 24 genes distributed over a 320kBinterval (from MICA to CLICI) what is the full range of genes that are associated with severe malaria? (2) Can we narrow down the functional polymorphism(s) responsible for the disease association by a combination of detailed haplotypic analysis and large-scale epidemiological studies in different populations? To address this problem I will begin by defining the haplotypic structure of the 320kb region around TNF in a West African population, and then use the most informative polymorphisms to fine-mapping disease association in large case-control and family-based studied of African children with severe malaria. This
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Controlling chirality in atomically thin quantum electronic materials' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Chirality is a foundational and unifying topic in science. It relates properties of elementary particles, to those of molecules in chemistry and biology (e.g. sugars), as well as the electromagnetic responses of artificial systems with non-superimposable mirror images. Besides, chirality bears an extraordinary potential for modern engineering, despite of the current lack of large, robust and actively controlled chiral signals needed to develop new applications.  The emergence of atomically thin quantum electronic materials with handedness has marked the ultimate twist in chirality. A wide variety of exotic and gigantic chiral phenomena are predicted to occur in these novel quantum systems.  Moreover, these effects are expected to be actively controlled by local fields, and therefore useful for applications. Nonetheless, such responses have yet to be detected, are puzzling and bring in new conundrums that demand investigation.  The purpose of CHIROTRONICS is two-fold. Firstly, the study aims to experimentally observe these striking chiral responses predicted to occur in chiral, atomically thin quantum electronic materials. Intriguingly, the exploration of these interdisciplinary effects will also contribute to shed light on central questions existing in many areas of knowledge where chirality is involved. Secondly, the project will demonstrate how chiral signals arising in these quantum materials can be actively controlled and enhanced by local fields, as well as harnessed to engineer a range of basic enantioselective and non-reciprocal optical and electronic devices. As such, CHIROTRONICS will pave the way to develop ultra-compact and disruptive 'chiral technologies', hardware components to be used in a myriad of novel applications including biochemical sensing or quant