RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'NTase Products and Cyclic Nucleotide Signalling' to be submitted under Horizon Europe.

assistant: **Abstract**

Survival of a cell depends on its ability to receive and process information coming from the environment. Second messengers are the key transmitters of information that rapidly amplify the signal inside the cell. Cyclic nucleotides (CNs) are the most diversified category of second messengers and are found in all organisms modulating diverse pathways. CNs are best studied in bacteria, where they have a variety of biological functions. In humans, the only described cyclic di-nucleotide is cGAMP, which elicits an antiviral immune response. cGAMP is rapidly emerging as a promising drug candidate in e.g., cancer immunotherapy. I hypothesise that additional CNs contribute to yet uncharacterized pathways in humans and my aim is to discover novel CNs and their signalling pathways. CNs are synthesized by nucleotidyltransferases (NTases) and many human NTases remain uncharacterized by the lack of activity in the absence of the cognate ligand.This project aims to reveal the molecular function of uncharacterized NTases and to discover novel CN signalling pathways in humans in immune and non-immune-related areas of biology. I will focus in Objective  on the activation of as yet uncharacterized NTases and in Objective  I want to identify CN signalling pathways involved in immune responses and beyond. The proposed experiments will provide me with candidates and precedence for CN signalling in humans other than cGAMP. The concept that yet uncharacterized CNs are involved in immune signalling as well as other pathways is highly innovative. Together, the well-studied activities in bacteria and the overall conservation of NTases in humans, further support fundamental involvement of CN signalling in humans. My proposed research will open up conceptually new modes of regulation in human bio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'An innovative screening protocol device for early identification of neonates at high-risk for Autism Spectrum Disorders', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Autism spectrum disorders (ASD) comprise an early-onset neurodevelopmental syndrome primarily characterized by impairments in social perception, cognition and communication, and a restricted pattern of interests and behavior. Without any doubt, infants and children with ASD greatly benefit from early behavioral intervention, therefore an early detection and treatment of ASD has been placed as a major health care priority. Unfortunately, nowadays, ASD diagnosis occurs at 2.5-4 years of age. In my previous ERC AdG Project, I proved that inborn predispositions to visual social stimuli (i.e., face-like patterns, eye-gaze and biological motion) is different between newborns at high-risk for ASD (HR, younger siblings of affected children) and newborns at low-risk (LR). Significant predictors for HR newborns were obtained and an accurate biomarker was identified. Starting from this, the goal of MoViS Project (Mobile Visual Stimulation) will be to develop, for the very first time, a simple and innovative tool for early screening and monitoring of neonates social behaviour by means of visual stimulation. This is an innovative and a promising project because, behind providing an important contribution in expanding our current knowledge about the ontogenesis of the ASD, the possibility of targeting high-risk infants during the first days of their life, via a behavioral marker for social orienting, could allow for a new generation of early therapeutic interventions for rehabilitation, starting in a time when brain plasticity allows reorganization of cortical circuits.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'European Researchers' Night 2021 in Malopolska' (ECOResearchers4Earth).

assistant: **Innovation**

European Researchers' Night (ERN) in Malopolska 2021 (Malopolska Researchers' Night) will be organised for the 15th time in our region. The event will be held in the hybrid formula (online and stationary activities) to response the participants needs and current pandemic situation. Such formula enable to attract larger group of people. Scale of the event is huge to show the wide scientific heritage and achieve project's goals: 8 cities of the Malopolska Region (Krakow, Tarnow, Nowy Sacz, Niepolomice, Oswiecim, Skawina, Chrzanow and Limanowa), approx. 60 locations in ca. 35 partner institutions (both those included in the project consortium and other partners involved in the ERN in Malopolska), approx. 1,800 different activities (including e.g. interactive workshops, demos and experiments, face to face meetings with researchers, science shows etc.) prepared by over 2,000 researchers, R&D employees and students in cooperation with 80 science clubs. ERN 2021 will be organized under the slogan ""Researchers are changing our world"". Particular emphasis will be placed on the role of researchers in the fight against various environmental threats, as well as against air pollution (incl. smog and climate changes) - they will share their discoveries with the ERN participants that aim to save our planet (incl. activities related to European Green Deal). An important distinction of the ERN among other events is that we focus 100% on interactivity. During the ERN, the researchers present their work combining learning with entertainment (edutainment), to make children and young people as passionate about science as possible. But the participants themselves will feel like real researchers performing unusual experiments under the watchful eye of their mentors. The project has European
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Light Night' (2014-2020).

assistant: **Innovation**

The 20th Century was characterised by a tremendous growth in our capability to develop ever more sophisticated electronic devices, which have fundamentally transformed the way society functions. We now sit on the threshold of a similar revolution due to developments in photonics, which seeks to exploit the photon – the elementary particle of light – in the same way that electronics is ultimately concerned with controlling the electron.Photonics has been identified as a “Key Enabling Technology” by the European Commission. Within Europe there are over 5,000 photonics based small companies and the sector employs nearly 300,000 people. In addition to forming the backbone of the Internet, the technology is already starting to revolutionise manufacturing, healthcare, lighting, displays and sensing.This proposed Researcher Night – Light Night - will coincide with the UNESCO Year of Light 2015, it will bring together the Aston Institute of Photonics Technology (AIPT), Aston University, with the Library of Birmingham and Community Arts Group, the Flatpack Film Festival, to deliver an afternoon and evening of public engaging content, informed by EC funded research, to raise the enormous importance of photonics research to local schools, community groups and library visitors.Light Night is designed to engage adults and young people in a programme which enables them to identify the importance of light to their lives, and experiment in light based activities. The Night will end with a performance by international sound electronic music artist Pantha du Prince, who will perform his most recent album Elements of Light at the Birmingham Symphony Hall.


**Keywords:** Photonics, public engagement, research
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'In-depth evaluation and analysis of existing life sciences networks, aiming at developing an internet portal integrating the European bioscience and biobusiness communities needs and resources' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The goal of the initiative is to survey major existing Life Sciences networks, in order to study the needs and feasibility of a global Life Sciences portal. The in-depth analysis of the existing networks will lead to the writing of the specifications of a European portal integrating all the features and requirements most used, in demand or still missing throughout the current regional, national and international networks.The writing of the portal specifications will be completed with a feasibility study indicating whether the European portal can become financially self-supporting. This study will propose technical alternatives vs sources of financing and will be presented in the format of a business plan.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Isis pulsed muon facility' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

Description:ISIS provides the world's most powerful source of pulsed muons and neutrons for condensed matter investigations. It is unique in Europe, and from its inception has attracted visiting researchers from most EC countries. Positively charged 'surface' muons are produced from a thin (5-10mm) graphite target placed in the extracted proton beam. The muons are collected and conducted to three experimental areas using a variety of magnetic and electrostatic beamline components. The complete installation is known as the 'EC Muon Facility' and was completed in 1994 following the award of a contract in the EC's Large Installation Plan (LIP- Framework Programme 2). Muon Spin Rotation or Relaxation (mSR) experiments are carried out on two permanently installed spectrometers, MuSR and EMU, and there is in addition a development beamline, DEVA, used for advancing new techniques. Research applications of pulsed mSR include the study of magnetic, superconducting, metallic, semiconducting, ion-conducting, amorphous and molecular materials.Application:Access to the ISIS Muon Facility is supported financially by the European Community's 'Access to Research Infrastructures Action of the Improving Human Potential Programme'. Applications for this support is available as part of the normal ISIS procedure for beamtime applications and requires the completion of the ISIS Application Form; there are two calls for experimental proposals in April and October each year. Electronic versions of the application form are available on the World Wide Web (http://www.isis.rl.ac.uk). Further information can be provided by Dr. Gavin Williams, Head of ISIS Diffraction and Muon Division, E-mail ßw.g.williams@rl.ac.uk±.Project Manager:Gavin Williams, ISIS Facility, Rutherford Appleton Laboratory, Ch
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'The social network for pilots, to make flying safer and cheaper'.

assistant: **Concept**

Only in Europe, 150 people lose their lives every year on light aircraft accidents. Flying is not a dangerous activity itself but the technology and regulations binominal is not optimal for this type of aviation. A lot can be done to improve safety margins. Over the years, aviation technology introduced in commercial aviation has led to a dramatic reduction of accidents. Tremendous investments in innovation brought traffic avoidance systems, flight data recorders, aircraft tracking... cutting edge tech that unfortunately cannot be transferred to light aviation straight away, just because of one single reason: high costs.Aeroclubs and flying schools are usually low margin businesses, not to mention leisure flying... Commercial aviation equipment costs are too high and regulators, aware of that, cannot impose them as mandatory. However, they are calling for tailored solutions to save lives while maintaining light aviation financially viable.Imagine a cost effective solution for light aircraft operators and regulators to enhance safety and reduce operational costs just by monitoring and analyzing metrics on every flight. Imagine a software, running in the smartphone of the pilot that could make many of the commercial aviation safety features, available to light airplane pilots. Imagine a social approach to it, a network where pilots can share flights, challenge themselves to fly safer and grow as a community. Imagine this is called AVIAZE.Inspired in the successful app Strava for runners, AVIAZE is the social network for pilots that makes flying safer and cheaper. With an addressable market of 5,5 Million pilots. We have registered +2500 flight hours and +1500 pilots so far, it is fully compliant with EU regulations. We’ve started to internationalize and it is supported by
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Two-dimensionAl tRansition-metal dichalcoGEnides-based recTifier for RF harvesting' in the context of a Horizon Europe call.

assistant: **Objectives**

In the present day, electromagnetic (EM) signals operating within the radio frequency (RF) range, including Wi-Fi frequencies of 2.4 GHz and 5.8 GHz, and cellular telecommunication spanning from 700 MHz to 2.7 GHz,  are becoming increasingly pervasive in indoor and outdoor environments. These signals constitute a prolific and continuous source of RF energy. Harnessing this RF energy holds great potential for powering future distributed electronics. However, before reaching the technology readiness level required for commercial utilization of RF harvesting, numerous factors must be taken into account. Among these considerations, the performance of diodes (rectifiers) is of paramount importance. Indeed, in most cases, the efficacy of the harvester heavily relies on the rectifier. This component ultimately enables switching-type conversions, such as  alternating current to direct current (acdc) conversions. The most crucial parameter for assessing the rectification capabilities of a diode technology is the short-circuit current responsivity or the voltage responsivity at zero bias. In this context, graphene-based rectifiers have exhibited remarkable characteristics, including a zero-bias voltage responsivity reaching up to 71 V-1. The TARGET RF project will continue to innovate in emerging materials and device architecture. Specifically, it will concentrate on investigating the responsivity of emerging two-dimensional (2D) technologies for rectifiers, particularly focusing on Rectifiers based on various Two-dimensional transition metal dichalcogenides (TMDs).This pursuit aims to enhance the efficiency of converting RF to DC power, particularly in RF low-power density scenarios. TARGET RF (24 months) will be hosted at the Granada University and will l be supervised by Prof.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Understanding the ph dependent catalytic activity in a model enzyme using protein electrostatics and protein engineering', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Research objectives and content In this project we propose to study the pH dependent electrostatic contribution to the pH-activity profile of a model enzyme, Fusarium solani pisi cutinase, as well as charge mutants thereof, with the goal of understanding in more detail one of the most important effects contributing to the pH-dependency of enzyme activity. We will use rational Protein Engineering to introduce, remove or move charges that we believe contribute to the pH activity profile. In all three cases we will substitute one residue in the native chain with another, and the residue to be changed will either be the charged residue or the neighboring residue. By modifying the latter we can move the charge without changing the nature of the charged residue. For all mutants we will measure the pH-activity profile using a standard lipolytic assay. We will also investigate the activity changes that accompany the changes in the media composition and correlate the observations to shifts in the electrostatic environment, that will be mapped on the molecular surface each protein (native and mutants). The 3D structures of the mutants will be solved in an X-ray laboratory collaborating with the host institution. ITC measurements will allow us to do thermodynamic studies of cutinase interactions (both native and mutated cutinase) with its substrats and inhibitors. DSC will be used in order to study structural transitions in native and mutated cutinase, as a function of time and temperature, in the absence and presence of substrat and inhibitors. Both measurements will be obtained under different media composition, where the electrostatic properties changed These studies will give us valuable novel insight into protein structure-function relationship. Training content (objective, b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Time is (not) on my side: Remembering victims of slow violence in a post-conflict and post-disaster setting (RESLOVI)' (RESLOVI) targeting Horizon Europe.

assistant: **Abstract**

What is happening when nothing is happening? And how can we study events that are ‘uneventful’? As a research field, memory studies has mostly focused on violent events (wars, conflicts and particularly the Holocaust) and their (public) remembrance. However, the proposed project (RESLOVI) attempts to move away from studying public remembrance of conflicts and proposes an innovative approach to viewing the aftermath of violent events. RESLOVI focuses on memories and experiences of displacement, caused by a war and a natural disaster. The project’s main research objective is to rethink memory of suffering and violence in a post-conflict and post-disaster setting by raising awareness of violence that is ‘unspectacular’, happening out of sight, and is not publicly remembered or even acknowledged as violence at all. RESLOVI counters the mainstream theories of memory studies by employing an innovative theory of ‘slow violence’. The project examines how people from a region in a post-conflict and post-disaster country grapple with and remember the experience of displacement, which is considered as a form of ‘slow violence’. The project entails 3 key objectives: (1) To contribute to innovative research on ‘slow violence’ by studying its characteristics in a region of post-war Croatia at the example of slow-moving transformations of the built environment that produced new vulnerabilities (displacements); (2) To introduce the ‘slow memory’ theoretical approach into studying how memories of Croatian population’s displacement are triggered and reframed in the context of new displacements happening due to new crisis situations; (3) To analyse the community response (‘mnemonic solidarity’) to suffering and to contribute to research on political significance of citizens’ mobilization