RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Targeting dendritic cell plasticity to modulate antigen-specific T cell recall responses in human' (2014-2020).

assistant: **Concept**

The human immune system has the ability to fight various infectious diseases or self-cells turning malignant. Dendritic cells (DCs) are innate immune sensors and professional antigen presenting cells that initiate the development of adaptive immune responses towards the formation of memory cells. Very important studies deciphered the various signals in DCs to effectively polarize naïve T cells. However, a significant gap of knowledge remains on how DCs can mediate and influence antigen-specific T cell recall responses.In this program, we aim to investigate how the different human DC subsets can modulate antigen-specific T cell recall responses directed against influenza (Flu) epitopes. To this end, we have designed a set of highly integrated work packages:WP1: Using a systematic experimental approach of challenging co-cultures of pure DCs (6 different subsets) and Flu-specific T cells from healthy subjects, we will generate a functional atlas revealing the impact of the different DC subsets on antigen-specific T cell recall responses. T cell response status will be assessed at the protein level using phenotypic and functional approaches on multimer positive T cells.WP2: Using CITE-seq technology together with cutting-edge system biology platforms, we will interrogate the transcriptomic programs and molecular pathways associated with antigen-specific T cell recall responses following stimulation with the various DC subsets.WP3: As a complementary analysis of the data generated in WP2, we will perform TCR repertoire analysis to compare the clonal composition of the responding antigen-specific T cells.This program represents an ambitious and promising project that will generate novel biological insights into fundamental immunological mechanisms of human DC-T cell communic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Research in new biomass-based composites from renewable resources with improved properties for vehicle parts moulding' (ECOPLAST) targeting Seventh Framework.

assistant: **Abstract**

The main objective of the project is the development of new biomass-based composites validated for the automotive industry by means of the adaptation of base biopolymers and the generation of new ones, using innovative treatments for fibre reinforcements and the additivation of the base polymer with novel fillers and nanofillers. The principal research line will be focused on the adaptation of available biopolymers (PLA, PHB) and the creation of a new protein-based biopolymer (SELP) for its use as the base matrix to be able to meet automotive standard requirements. To achieve that advance, it is indispensable to improve the thermal characteristics of these polymers, the hydrolysis resistance, the dimensional stability and the volatile emission. Therefore, this project will develop several new reinforcements and novel additives like nanofillers, mineral fillers and treated natural fibres (nanocellulose) to be compounded with these base polymers in order to create new biocomposites. Accordingly, it will be used: a. Nanofillers to increase the thermal resistance. b. Natural fibres and nanocellulose to enhance the dimensional stability and the mechanical resistance. c. Mineral fillers to reduce the moisture absorbency. Another important goal in this project is the adaptation of conventional processing techniques (polymers compounding, injection moulding and thermoforming), widely used in the automotive industry, and the design of new ones tailored to these biocomposites. The challenge here will be to overcome the problem of degradation because of the extreme thermal conditions and the moisture absorbency.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The energy-converting mechanism of a modular biomachine: Uniting structure and function to establish the engineering principles of respiratory complex I' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Complex I (NADH:ubiquinone oxidoreductase), one of the largest membrane-bound enzymes in the mammalian cell, uses the reducing potential of NADH to drive protons across the inner mitochondrial membrane and power ATP synthesis. It is a keystone of metabolism, crucial for survival of human cells, and a primary site of mitochondrial dysfunctions and clinical disease. Complex I is also an efficient energy-converting biomachine, which shares conserved subunits, a molecular architecture, and modular design with prokaryotic type-4 hydrogenases, such as formate hydrogenlyase (FHL), that contribute to microbial H2 metabolism and geochemical cycles. Detailed cryo-electron microscopy (cryoEM) structures have defined the physical framework of the catalytic machinery in complex I, but there are wide knowledge gaps in central aspects of how it works, and no firm foundation of functional data to distinguish competing mechanistic proposals. ModularBioMachine will combine advanced strategies for structure, nanoassembly, function and genetics to transform knowledge of the reversible energy-transducing mechanism of complex I and FHL, exploiting their similarities and differences for enhanced insights and impact. It will exploit two powerful complex I platforms, complex I-containing proteoliposomes, which enable cryoEM under precisely defined conditions during energy-linked catalysis, and complex I from Paracoccus denitrificans, which combines cryoEM, genetics and advanced functional analyses in a single system – and extend both to study FHL. Focussing on three crucial knowledge gaps, the power stroke at the heart of energy conversion, the clockwork mechanism that defines the moving parts, and the proton wiring diagrams, ModularBioMachine will deliver a coherent, integrated understanding o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Mediterranean Cities in Conflict: Urban Wars, Inter-Ethnic Coalitions and the Prospects for Peaceful Coexistence in Lebanon and Israel/Palestine, 1918 to the present""' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

This research aims at mapping inter-ethnic relations in contested cities in the Eastern Mediterranean by comparing urban dynamics in Lebanon, Israel and Palestine. While most of the geopolitical scholarship on ethnonational conflicts in the region has focused on the territorial struggles between rival nation-states and other regional actors, this project proposes a historical anthropology of intra-urban borderlands consisting of ethnic groups sharing the same city. Political adversaries, Lebanon and Israel share nevertheless a fundamental commonality: they both politicized the Ottoman legacy of communal autonomy and religious sectarianism. Rescaling ethnic conflicts from the regional to the urban arena, this project proposes a “bottom up” analysis of the political mobilization of territoriality, identity, religion and nation. To this end, the research examines how urban space, violent conflict and national identities have been both represented and produced in contested cities since the collapse of the Ottoman Empire. Against the background of a century-long conflict between the Jewish and Palestinian national movements in Israel/Palestine and the sectarian struggles over political power between Christians and Muslims in Lebanon, this project studies the relations between opposing community-building efforts in war-torn urban settings. Focusing on cities like Beirut, Sidon, Jerusalem, Jaffa and Haifa, I historicize the problematic place they occupy in the popular, political and sociological imagination. Through ethnographic and historical analysis I show how Jewish, Muslim and Christian citizens, implicated in relations of interdependence, strive to define their respective collective identity in relation to the nation. These processes serve as a lens through which the res
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'EMBL Interdisciplinary, International and Intersectorial Postdocs' in the context of a Horizon 2020 call.

assistant: **Objectives**

The EIPOD programme was developed in 2007 with the objective of making use of the excellent scientific environment available at EMBL to support an innovative fellowship programme focused on interdisciplinary research training for postdoctoral fellows. EI3POD is designed to enrich and significantly build upon the very successful EIPOD programme and bears a significant number of novel features for scientific collaboration as well as vocational skills training and career development. The I3 in EI3POD stands for:1.    Interdisciplinary2.    International/inter-institutional3.    IntersectorialIt offers three different modules each focusing on one of the three “I’s” as an expansion and significant enrichment of the original EIPOD scheme. All postdoctoral candidates applying under the EI3POD scheme will be offered the choice from among these three specializations. The specialization process will be supported by a career development advisor and accompanied by a set of training requirements to prepare candidates for making informed decisions about their project direction and career goals.


**Keywords:** Interdisciplinary, International, Intersectorial. Postdoc, Training, Career Development, Industry, Entrepreneurship, Outreach, Ethics
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The Biodiversity, Systematics and Guide to the Identification of Marine Benthic Ciliates' to be submitted under Seventh Framework.

assistant: **Abstract**

Ciliated protozoa (ciliates) are important in terms of their diversity, ecology, pathogenesis and as indicators of environmental quality. Marine benthic ciliates, however, are rather poorly known due to a lack of modern treatments and taxonomic expertise. The objectives of this project are: (1) to increase knowledge of local and global species diversity. A faunistic study of benthic ciliates from UK coastal waters will be carried out using classical microscopy and modern molecular methods. The data for selected UK and Chinese species will be compared in order to assess their geographical distributions. (2) To increase understanding of phylogenetic relationships among ciliates and thus help stabilise the Tree of Life. For this, morphogenetic and molecular data for selected taxa will be used in phylogenetic analyses. (3) To develop a web-based guide to the identification of marine benthic ciliates. This will be constructed within a Scratchpad (http:// scratchpads.eu/) which is a tool developed at the NHM that allows for species descriptions to be made available on the web. The present project will extend this functionality by adding an interactive key based around structured descriptive data. New taxa in the correct format will automatically add them to the key without further intervention. Dr Hu is a top-class researcher from China who specialises in marine benthic ciliates. Expertise in this field is increasingly rare in Europe and has led to a lack of understanding of the importance of benthic ciliates in marine microbial ecology and their contribution to species diversity. This project will help to: enhance Dr Hu&apos;s reputation as a leading authority on marine benthic ciliates; increase his network of European contacts; by developing the open-access web-based guide
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Design & Manufacture of a ground based structural/systems demonstrator (Phase 2)' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

The Natural Laminar Flow airfoil is considered to be one of the key technologies to reduce drag and thus improve the performance of an aircraft, therefore reducing emissions. The Natural Laminar Flow Wing is recognized as a potential key technology for the next generation of aircraft.The requirements of a Natural laminar flow wing differ significantly from a conventional turbulent wing, requiring changes to both the architecture of the wing, the aerofoil definition and the detailed design and manufacturing concepts.The performance of a natural laminar flow wing requires very tight surface roughness and waviness tolerances and contamination free surfaces in the areas where laminar flow is to be maintained.  Alternative leading edge moveable concepts and novel leading edge/wingbox attachment concepts, and extremely slender LE sections also have to be addressed in the design.In Phase 1 of the programme, the problem of how to achieve an aerodynamic surface of sufficient quality to support natural laminar flow has been addressed by GKN.  In particular a number of mechanical joint concepts have been evaluated against a very tight set of criteria including steps and gaps, surface finish, aerofoil profile, waviness and fastening techniques.Phase 2 (this project) will form the basis for the further development of the concepts for a ground-based demonstrator.  The work on LE design is focused into five specific development activities:  Innovative Wing Leading Edge Ribs and Integrated Leading Edge Cover solutions;  Kruger flap integration into the D-Nose; Continued Investigations on potential Wing Ice Protection (WIPS) solutions; Lightning Strike protection for the Leading Edge zone; Bird strike risk assessment.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Innovative COoling system for embedded Power Electronics' (ICOPE) targeting Horizon 2020.

assistant: **Abstract**

The main goal of this project is the design of innovative and efficient air cooled heat sinks to cool the power electronics modules that are a key component of the more electrical aircraft power management centre design. The new design is expected to be developed in two stages. The first one should be covered by the implementation of Annealed Pyrolytic Graphite (APG) and folded brazed fins, while in the second the integration of Metal Matrix Composites (MMC) is expected. The final target of the development is the reduction of weight of the whole power management system (bay integrating four heat sinks), while maintaining an efficient and reliable cooling.Coming from advances in the power semiconductors field, by the use of high-temperature and more efficient materials such as Silicon Carbide (SiC) and Gallium Nitride (GAN), the thermal management strategy could take into consideration the implementation of air cooled solutions, which are expected to reduce the overall weight comparing to liquid or two-phase flow solutions, while also adding some benefits in terms of reliability and maintenance aspects.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'VERTICILLIUM WILT IN TREE SPECIES; A CONCERTED ACTION FOR DEVELOPING INNOVATIVE AND ENVIRONMENTALLY SOUND CONTROL STRATEGIES' to be submitted under Fourth Framework.

assistant: **Abstract**

This Concerted Action contributes to the Objectives addressed by concertation(area 6) by coordinating research in area 4 (Agriculture, forestry and rural development) of the programme. It concerns mainly the topic areas Plant health" (441) and 'Agriculture-environment interactions' (412), although the research is also related to areas 432 (Biomass production) and 453 (Forest conservation and protection).The proposal involves 8 research groups from 5 EU-member countries. The general objectives are: A. Coordination of European research on verticillium wilt in tree species B. Developing innovative and environmentally sound control strategies C. Preparation of a compendium on verticillium wilt in tree species D. Compiling a proposal for shared cost research.The structural philosophy of the project is to bring together the eight participatin groups, currently working on several aspects of Verticillium Wilt in different member countries, aiming at interchanging ideas and scientific knowledge, standardization of methods and promoting future cooperation on the basis of a SC project. During the three meetings which have been planned within a 2-year period a Compendium on Verticillium Wilt in trees and also a RTD-proposal will be prepared.The research activities, that will be coordinated, include three main research areas1. Identification of resistant germplasm2. Improving pre-planting risk assessment procedures3. Epidemiological aspects related to biological control.Within these three research areas twelve research tasks have been identified. Integration of the results from the three research areas with present information will prepare the basis for developing innovative and environmentally sound control strategies."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Precursors of logical reasoning in human infants' (PreLog).

assistant: **Concept**

There is no other field that is more controversial in psychology than that of human reasoning. This project advances a novel theoretical framework focused on the nature and the origins of rationality and could potentially resolve some of these controversies. Theories targeting the mechanisms that allow rational inferences have defined rationality as a function of how much reasoning adheres to formal rules of probability calculus and logic. Classical research with adults and older children collected a large amount of data both in favor and against human rationality, suggesting that reasoning abilities follow a slow maturation. Recent findings on infants’ probabilistic reasoning, including my own earlier research, however, do not support this view. Already preverbal infants seem to form expectations about probabilistic events in accordance with Bayesian rules of inference (Téglás et al, 2011). Here I argue for a similar paradigm change in a related domain, that of deductive reasoning.In contrast to earlier accounts, I propose that even preverbal infants may possess a core set of logical operations that empower them with sophisticated inferential abilities. First, I focus on the representational precursors of this competence. I argue that infants recruit specific abilities to exploit the conceptual structure of specific event categories that enable them to form logical representations. Thus, information could be stored in a format that can potentially serve as input for subsequent inferences. Further, I will investigate infants’ core logical operations and test how they integrate multiple steps of inferences. This system - indispensable for integrating different bits of knowledge - helps infants to discover information that was not actually present in the input. Such inves
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Monitoring for pulsed plasma processing - new plasma probes for advanced manufacturing (MPPP)' (MPPP) targeting Fifth Framework.

assistant: **Abstract**

For many of the processing steps in the manufacture of thin film microelectronic devices, plasma is the only way to generate the required active chemical species. In the processing of ultra-thin layers with steady-state plasma there are problems associated with charging and breakdown of dielectric layers. Pulsed plasmas offer a way to overcome these problems, but new methods are required for the monitoring and control of such plasmas. The aim of this proposal is to develop and test the new diagnostic instrumentation required for pulsed plasma processing. Time-resolving Langmuir probes and optical spectrometry will be developed to diagnose the plasma, and optical reflectrometry will be used to monitor the film growth. The test bed for the validation of these new techniques will be a pulsed laser deposition facility for the manufacture of SQUID magnetometers. However, this new instrumentation will find application in a wide variety of pulsed plasma processes.