RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Development of DIALIVE, a novel Liver Dialysis Device for the treatment of patients with Acute on Chronic Liver Failure (ACLF)' under Horizon 2020.

assistant: **Concept**

Liver disease incidence is increasing and about 170K patients die from liver failure each year in Europe. In liver failure, the accumulation of protein bound toxins and increased susceptibility to infection cause multiorgan failure and death. Liver transplantation is the only treatment known to prolong the life but is limited by availability of organs. A clinically efficacious ‘liver dialysis device’ is an unmet clinical need. The ALIVER Consortium has developed and optimised a novel ‘liver dialysis device’, DIALIVE. The DIALIVE device is protected by world-wide patents and is based upon our discovery that (i) albumin, a circulating protein involved in detoxification is reduced irreversibly in function and (ii) endotoxemia contributes to increased risk of infection in liver failure. DIALIVE incorporates albumin removal and replacement and, endotoxin removal and is a TRL5. In animal models of liver failure, DIALIVE was shown to be easy to use, safe, reduced endotoxemia and, improved albumin and immune function and, prolonged survival. The ALIVER Consortium, which is comprised of experts in liver failure, SMEs and charities proposes to perform clinical trials of DIALIVE in patients with acute on chronic liver failure (ACLF). During the grant period a CE-mark will be obtained and the device will progress to a TRL7/8. Consultation with Regulatory bodies confirms that if the trials are successful, a CE-mark is highly likely. Grifols, a large plasma proteins company is a potential licensee of the technology if the studies proposed by the ALIVER Consortium are positive. We plan to take the project through regulatory and ethics approval and perform a study to define its safety in ACLF patients in 18 European hospitals; define health economic benefits to the EU and define a reim
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'TRANSPARENT ARTIFICIAL INTELLIGENCE AND AUTOMATION TO AIR TRAFFIC MANAGEMENT SYSTEMS'.

assistant: **Objectives**

Recently, Artificial intelligence (AI) algorithms have shown increasable interest in various application domains including in Air Transportation Management (ATM). Different AI in particular Machine Learning (ML) algorithms are used to provide decision support in autonomous decision-making tasks in the ATM domain e.g. predicting air transportation traffic and optimizing traffic flows. However, most of the time these automated systems are not accepted or trusted by the intended users as the decisions provided by AI are often opaque, non-intuitive and not understandable by human operators. Safety is the major pillar to air traffic management, and no black box process can be inserted in a decision-making process when human life is involved. In order to address this challenge related to transparency of the automated system in the ATM domain, ARTIMATION focuses on investigating AI methods in predicting air transportation traffic and optimizing traffic flows based on the domain of Explainable Artificial Intelligence (XAI). Here, AI models’ explainability in terms of understanding a decision i.e., post hoc interpretability and understanding how the model works i.e., transparency can be provided in the air traffic management. In predicting air transportation traffic and optimizing traffic flows systems, ARTIMATION will provide a proof-of-concept of transparent AI models that includes visualization, explanation, generalization with adaptability over time to ensure safe and reliable decision support.


**Keywords:** ARTIFICIAL INTELLIGENCE, TRANSPARENT, AIR TRAFFIC MANAGEMENT, Explainable
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'MULTI-PHYSICS METHODOLOGY FOR PHASE CHANGE DUE TO RAPIDLY DEPRESSURISED TWO-PHASE FLOWS'.

assistant: **Innovation**

A multi-physics methodology is proposed to couple CFD calculations with models for phase change of rapidly depressurised mist of a fire suppression system. The methodology combines existing models with newly developed ideas with considers the coupling between large and small scales. The new models aim to describe the penetration of a two-phase flow and phase transitions into the confounding space and will be implemented as a user defined function in a tool chain and coupled with the nearfield CFD calculation. Both, a Lagragian and a Eulerian formulation will be followed using existing commercial tools and “in-house” multiphase solvers. Finally, one experiment is proposed to validate the numerical results in one relevant case.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Low cost precision micro-engineered components for microelectronic applications' (MEOPEC) under Fourth Framework.

assistant: **Objectives**

The industrial objective is the provision of a European advanced product capability for precision micro-engineered components, used in optoelectronic systems and applications. The existing materials and manufacturing processes used will also be considered to identify possible improvements in product functionality or areas of application, with a further target of unit cost reduction. Such a facility would enable users of these components to purchase them within the EC, in response to the current position whereby virtually all components are sourced from Japan.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Systematic and orchestrated deployment of safety solutions in complex urban environments for ageing and vulnerable societies' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

The emergence of complex urban mobility environments where unknown interactions between different types of vulnerable road users (VRUs) and between VRUs and motorised vehicles poses the need for a clear understanding of user behaviours, fair and optimised use of public spaces as well as age friendly urban safety action plans and assessments, capitalising on the benefits that technological innovations and the plethora of available data can offer in advanced accident analysis, towards achieving EU’s ‘Vision Zero’ for zero fatalities in road transport by 2050. SOTERIA aims to accelerate the attainment of this Vision for VRUs through a holistic framework of innovative models, tools and services that enable data driven urban safety intelligence, facilitate safe travelling of VRUs and foster the safe integration of micro-mobility services in complex environments. At the operational level SOTERIA uncovers unexplored behavioural characteristics of VRUs and engages Living Lab communities in social innovation activities for the co-creation of urban safety solutions and infrastructure designs. Simulation models and explainable AI driven analytics are developed for supporting policy decisions and informing interconnected services that support VRUs in safe and clean travelling. On-vehicle sensors and connectivity are fostered enabling minimisation of risky situations and behaviours. The approach is validated in four thematic demonstrations and through the SOTERIA network of eight cities, addressing different types of VRUs.


**Keywords:** behavioural modeling, social innovation, explainable AI, mobility demand prediction, C-ITS, micro-vehicle telematics, Safe Routing, behavioural change systems, space modelling, accident analysis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Microbial Expression Platform for Membrane Integrated Enzymes' (2007-2013) targeting Seventh Framework.

assistant: **Abstract**

We wish to explore how and why the architecture of the DNA code for membrane proteins vary between kingdoms and affect protein production under different growth conditions - with an unprecedented systematic approach. At the core of biotechnology is heterologous expression of proteins, i.e. to transfer genes into foreign hosts like microorganisms for protein production. One of the key challenges in protein production relates to the degeneracy of the genetic code. Genetic information flows from DNA via RNA into proteins, but the code is degenerate because different DNA/RNA-nucleotide sequences can be translated into the same protein sequence. In the DNA and RNA code, three nucleotides (a codon) are translated into one amino acid residue, and amino acids can be encoded by up to six different “synonymous” codons. Substantial evidence, from studies of soluble proteins, points to a role for this “deeper layer” of the genetic code in the proper timing of co-translational protein folding. For example, regions rich in rare codons may slow down translation to allow time for folding of specific secondary structures. However, since codon usage is not conserved like the universal genetic code, protein-folding information hidden in the DNA code is difficult to transfer from one organism to another. As a result, heterologous expression often leads to misfolded, non-functional proteins. Very limited experimental evidence exist on the connection between codon usage and production of functionally active proteins and in the case of membrane-integrated protein, no such systematic studies have been performed. The knowledge gained will be exploited to engineer new scaffolds for microbial factories. Successful designs will be a novel, invaluable tool in molecular biology and may spawn future
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Excitatory synapses in the neocortex: a calcium study imagining of pre and post synaptic elements with a molecular characterization by single cell rt-multiplexpcr' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

In contrast to the wealth of information gathered in neuropsychology since the advent of imaging technologies, the cellular physiology of the neocortex is yet underdeveloped. The aim of this work is specifically to understand what determines the functions and the characteristics of excitatory synapses between pyramidal neurons and the different types of interneurons of the neocortex. This will be achieved by combining electrophysiological recordings of pairs of neurons with calcium imaging at the single synapse level using multiphoton microscopy, single RT-multiplexPCR and anatomical reconstruction of the connected neurons. The calcium imaging will detect transients in both pre- and postsynaptic elements and involve the development of new multiphoton laser scanning microscope hard- and software. The single cell RT-multiplexPCR will be expanded using DNA microchip technology to detect the expression of 100 genes relevant to cell-type identification and synaptic transmission.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Netherlandish Paintings in Ledreborg Palace: A Multi-Disciplinary Research of circa 600 Paintings' (NePLeP).

assistant: **Concept**

More than 600 Netherlandish seventeenth century paintings decorate the walls of Ledreborg Palace (Lejre, Denmark). The painting collection, of which a large share presumably was brought together in the first half of the eighteenth-century, consists mostly of mass-produced paintings, a novel commodity of the seventeenth century. Fascinatingly, Ledreborg Palace is not the only collection in Denmark which displays a strong emphasis on Netherlandish paintings: at least 2 other (also not disclosed) collections are known. However, the question why the Danish seem to have had a strong interest in Netherlandish paintings remains unanswered. This research will contribute to understanding the strong interest in Netherlandish paintings in Denmark during the seventeenth through eighteenth centuries by focusing on the collection of Ledreborg Palace. All the paintings will be thoroughly examined from an art historical viewpoint, however, also technical studies such as infrared and X-ray images will be carried out in order to understand also the artists working methods in their mass-production endavours to supply the entire European continent with affordable paintings. The overall result will be an improved understanding of the spread of Netherlandish art and the means by which this could be done. All the achieved data will be accessible for researchers and the public through an open-access database with 600 annotated paintings including an art historical and technical study of a carefully selected part of these hitherto undocumented and unstudied paintings. Simultaneously the latest expertise in socio economic art history will be employed to situate the paintings in a European framework of the seventeenth century and their importance to the society of today. The project will provide
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Fast-ignitor physics with high irradiance lasers'.

assistant: **Concept**

Research objectives and content The objectives and content of this project are: 1) to perform an experiment to investigate hot electrons generation and transport (when an intense laser beam interacts with plasma) by using the technique of Ka x-ray spectroscopy. Moreover we plan to measure the temperature of hot electron heated region by taking advantage from time resolved K-shell spectroscopy. 2) to perform an experiment with the aim of obtaining scaling laws giving the suprathermal temperature as a function of laser intensity, plasma density and gradient lenght. The electron temperature will be measured directly with a magnetic spectrometer. The plasma parameters will be modified by varying the time duration between the creation pulse and the interaction pulse and the energy of the first one. 3) to realise news models for hot electron transport. This work will be based around the using of hydrodynamic codes. Training content (objective, benefit and expected impact) The priority objective is to give an important contribution for fast ignitor field and consequently a big benefit for Inertial Confinement Fusion research.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Cinephilia, Urban Spaces and Affective Memories: Mapping cinephilic places in 1950s-1980s Lisbon' in the context of a Horizon Europe call.

assistant: **Objectives**

CineTopos explores the intersection of cinephilia and topophilia. The first refers to the love for cinema, a love composed of moments, rituals, and artifacts; while the second refers to the ‘love of place’, the emotional connection that individuals have with specific places. In effect, the concept of ‘topos’ includes both a physical and a mental space. I argue that both concepts can be connected, and I will address cinephilia as a ‘site-specific’ phenomenon, deeply connected to a specific location and geography. My approach will contribute to an underexplored area, as current discourse generally focuses on the relationship between cinema and urbanism. Unlike studies that examine how films depict cities or how cities are shaped by the evolution of movie theatres, my research will delve into the social spaces linked to cinephilia that extend beyond cinemas or film clubs. Indeed, cinephilia was shaped by cinephilic places par excellence - cinemas, ciné-clubs, video rental stores – but also 'cinephilic para-spaces' – such as cafés and restaurants where cinema was discussed, and neighborhoods frequented by cinephiles. As a case study, I will focus on Lisbon from the 1950s to the 1980s. Lisbon is a peripheral and often overlooked capital within Western European film studies. However, within Lisbon, one can find many ‘cinephilias’, with their variations, communities and subcultures. Distinctions can be made based on social class and wealth, as well as on cinematic ‘schools of thought’. I aim to map the spaces and places that were significant for cinephile and film culture over time (1950-1980), including key social and political changes like the Carnation Revolution, and to identify which elements persist in contemporary Lisbon. This topic lends itself not only to academic dis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Sustainability tools and targets for the urban thematic strategy'.

assistant: **Innovation**

The Urban Thematic Strategy (UTS) is one of 7 Thematic Strategies of the 6th Environment Action Programme. This is a new way of developing environmental policy for complex priority problems that require a holistic approach. The key organising principle for the UTS is sustainable development underpinning . The preparatory work to ensure effective implementation of the UTS in 2005 needs to be undertaken in the next 15 months. In particular, appropriate mechanisms must be put in place to monitor and assess pro gress during the Strategy, and to provide clear, realistic and appropriate medium term targets for the Priority Themes. The STATUS Project follows the central objective of the relevant SSP, Task 1, in aiming principally to develop locally-relevant targets for local authorities (LAs) across the EU to self-assess progress with urban sustainable development. To do this, a user-friendly on-line tool will be designed onto which will be entered a range of targets and related indicators. These targets will be dev eloped, through building on the synergies between the UTS themes, the Aalborg Commitments, Urban Audit, and European Common Indicators, and through intensive involvement of LAs at key stages of the Project. The tool will use the Lasala On-line approach as a starting point for its development. With this tool, LAs will be able to consult all the targets, and receive useful information on them. They can then select targets relating to the local context and enter relevant baseline data against these. It is a nticipated that a more refined version of the Prototype Tool would need to be developed (subsequent to the STATUS project) to permit LAs to regularly input data showing progress on the selected targets, and then receive feedback on this. The Prototype too l will be
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Novel AI-based system for orthopedic surgery to help surgeons fully automate the pre-operative planning of knee osteotomy' (PeekMedAuto), addressing dissemination and exploitation.

assistant: **Impact**

Peek Health S.A.’s overall mission is to develop innovative technological solutions for pre-operative planning of orthopedic surgeries; increasing the quality of healthcare services, decreasing the overall cost of care, and providing added value to surgeons, patients, and partners. Based on a successful manual version with significant market traction -PeekMed®- Peek Health introduces the innovative AI-based PeekMed-Auto, the first system that fully automates pre-operative planning for osteotomies around the knee (correcting bowlegs or knock knees); a surgery allowing patients to postpone knee replacement for several years, or avoid it altogether. The need for this innovation became apparent by the reported difficulty of planning osteotomies by surgeons due to its complexity and limitations of tools available. Through significant and disruptive impact, PeekMed-Auto will establish Peek Health’s position in the market, generating >€40M in revenue by 2026, and a cumulative profit of ~€40M.


**Keywords:** Machine learning, statistical data processing and,Data analysis,Deep learning,Automation,Software tools,Surgery,AI-system,Orthopedics,System integration,Preoperative planning