RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Efficient and Light Electrical Compressor for Tilt-Rotor Aircraft', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The main objectives of the proposed ELECTRA project are:1.The development of an optimal architecture for a bleedless cabin pressurization system (CPS)2.The development, manufacturing, test and qualification of CPS hardware suitable for flight testing on the next-generation tiltrotor technology demonstratorTo achieve the objectives, ELECTRA will:1.Set up a simulation platform2.Perform system-level and equipment-level trade-off analyses3.Develop equipment hardware: cabin pressure management system, electrical compressor, electronic control unit and its firmware, outflow valve and several other system components4.Develop a test rig for hardware testing, emulating the cabin pressurization system, and test the developed hardware5.Develop a prototype qualification unit and perform environmental qualification tests6.Develop a prototype flight unit, cleared for flight on the next-generation tiltrotor technology demonstratorELECTRA contributes to task 1.6.3 of the Joint Technology Programme, “Pressurization and Environmental Control System Components Design, Manufacturing and Testing”, by contributing to these JTP objectives:•Reduction of carbon emissions through improved energy efficiency•Reduced cost of ownership•European industrial leadership on ‘Smart, Green and Integrated Transport’•Improving mobility through new mobility concepts (more flexible, resilient, effective and affordable)•Spin-off from research innovation activities to other aircraft


**Keywords:** Aircraft compressor, Cabin compressor, Electric compressor, Cabin pressure control system, More-electric aircraft
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Aqua Research Infrastructure Services for the health and protection of our unique, oceans, seas and freshwater ecosystems' (AQUARIUS).

assistant: **Innovation**

AQUARIUS will provide a highly comprehensive suite of integrated research infrastructures appropriate to addressing significant challenges for the long-term sustainability of our unique oceans, seas and freshwater ecosystems. For the first time, diverse research infrastructures will be combined to facilitate the work of researchers and key stakeholders focused on challenges and opportunities for both marine and freshwater systems. An impressive range of 57 research infrastructure services will be made available to include research vessels, mobile marine observation platforms, aircraft,  drones, satellite, sensors, fixed freshwater and marine observatories and test sites, experimental facilities, and sophisticated data infrastructures. AQUARIUS will support the development phase of the EU Mission to Restore our Ocean and waters by 2030, the Sustainable Blue Economy Partnership, the European Green Deal, and international climate initiatives. It will also be an essential component in achieving the European Digital Twin of the Ocean and the UN Decade for Ocean Sciences. The needs of researchers will be met through a robust and transparent system of transnational access funding Calls, facilitated by centralised user-friendly access portal. The Call programme will be informed through stakeholder engagement and brokerage events. Projects to be selected for Access must convincingly integrate multiple infrastructures and contribute to the core policy objectives of Mission Ocean, that is, to protect and restore marine and freshwater ecosystems and biodiversity; to prevent and eliminate pollution of our oceans, seas and waters; and to ensure a sustainable, carbon-neutral and circular blue economy. A thematic and geographic focus will be the hallmark of the proposed transnational C
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Joint Doctorate in Geoinformatics - Enabling Open Cities' (GEO-C) under Horizon 2020.

assistant: **Objectives**

Urbanisation has been a key trend for centuries and is expected to continue throughout the 21st century as well. Cities have to continuously strive to provide a sustainable, safe and liveable environment for their ever-increasing populations. In recent years, the term ‘smart cities’ has been coined for initiatives that monitor and analyse different aspects of urban life, and manage service provision intelligently. A key gap in this area relates to how people can understand the processes driving smart cities and their services, and how they can gain a sense of control rather than being controlled by the services provided by a smart city. GEO-C aims to contribute methods and tools to realise smart and open cities, in which all groups of society can participate on all levels and benefit in many ways. The complementary strands of research in GEO-C will lead to an improved understanding of how to build open cities and will produce a prototypical open city toolkit. The toolkit will contain software, libraries, apps and frameworks that enable cities to easily set up or adapt key services, processes and analyses. This research area provides challenging and rewarding topics for early-stage researchers to carry out a PhD. These topics include, for example, participation across all ages and groups of society, the assessment of the quality of life, and fundamental urban services. As the 15 PhD researchers will become experts in the toolkit, their career perspectives will benefit greatly from the toolkits’ public and open release. To further increase the impact of GEO-C and to also optimise career perspectives of the PhD researchers, the city councils of Münster, Castellón, and Lisbon and several companies across Europe will be closely involved as associated partners. They provide i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Microscale Dynamics and Non-Maxwellian Equilibria: Decoding Collisionless Processes in the Space Plasmas' in the context of a Horizon Europe call.

assistant: **Objectives**

Plasma is the most common state of matter in the Universe. In most plasma environments, such as accretion disks, intracluster medium, and the heliosphere, the interparticle collision frequency is much smaller than the characteristic particle time scale, so the plasma is effectively collisionless. As a result, the velocity distribution function of charged particles, such as electrons, is not bound to the Maxwell-Boltzmann thermodynamic equilibrium. Nevertheless, stable non-Maxwellian equilibria can exist in collisionless plasma. In particular, recent advances using Lynden-Bell statistical mechanics theory and kinetic Vlasov theory of electrostatic turbulence suggest that non-Maxwellian equilibria are universal. This project aims to understand the varieties of such equilibria and their universality in the heliospheric plasma. To this end, we will propose an innovative data-driven approach, combining in situ observations from state-of-the-art spacecraft, theory, and numerical simulations, to characterise the non-Maxwellian equilibria. Using in situ spacecraft observations, we will statistically describe the different non-Maxwellian equilibria in the heliosphere. In addition, we will use kinetic Vlasov theory and numerical simulations to show how microscale turbulence shapes these equilibria through the interaction between electrons and electromagnetic fields. Together, these steps are designed to help us understand and conceptualise the statistical thermodynamics of a collisionless, turbulent plasma at a new level.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Dissecting the Functional and Therapeutic Impact of Somatic Copy Number Alterations (SCNAs)' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

In 1914 Theodor Boveri described abnormal chromosome counts in cancer cells and speculated that these alterations are the driving force of cancer. Almost 100 years later it became clear that somatic copy number alterations (SCNAs) are one of the most striking characteristics of cancer genomes. SCNAs comprise deletions and amplifications of whole chromosome arms and therefore alter the expression patterns of several hundred genes simultaneously. These alterations show defined patterns suggesting selective pressure, and thus likely contain multiple driver genes, which can shape several tumorigenic properties. Therefore, studying how these events contribute to tumor development will be fundamental to understand cancer biology and develop targeted cancer therapies. However, whereas the function of recurrently mutated driver genes can be readily assessed, studying SCNAs remains challenging so far. This project will overcome these limitations by combining our unique ability to model liver cancer in vivo and in vitro with innovative CRISPR-based genomic engineering technologies. First, we will generate large chromosomal deletions in murine livers and human-derived liver organoids by CRISPR technologies and assess their functional role in cancer development. Furthermore, synthetic lethal interactions generated by these deletions will be evaluated on their therapeutic potential. Additionally, driver genes and driver gene-combinations of amplified chromosomal regions will be investigated using a novel CRISPR/Cas9-based mouse model for endogenous gene activation and chromosome engineering. Finally, we will exploit a novel concept for targeting cancer cells with specific amplifications. Our unique approach will for the first time systematically investigate the functional role of SC
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Evolving drugs- with a new proprietary technology- to fit the therapeutic needs of the european pharmaceutical industry' in the context of a Fifth Framework call.

assistant: **Objectives**

Evolve intends to redesign the entire process of discovering and optimising drugs. It aims to replace the traditional" methods used throughout the pharmacy industry with a technology platform (Watchmaker TM) based on genetic constructs that generate and then evolve small molecules until compounds that "fit" the desired therapeutic characteristics have been obtained. Evolve will provide access for European pharmacy companies to produce new complex molecules for therapeutic use in a hitherto unknown short time span, at higher efficiency and lower price. Applications of Watchmaker TM include:1.Provision of novel genes and proteins,2.Provision of novel functional molecules,3.Development of candidate drugs4.Production in scale of high value compounds. Evolve holds the potential to transform the entire process through which the European pharmacy industry will discover novel candidate drugs and greatly improve both the economics of the process and the diversity of structures. Evolve holds four patent applications to protect its technology. Further patent applications to be prepared. Evolve management has held top positions in leading European biotech companies."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Soft Matter Nanotechnology to Create Life-Like Machines' to be submitted under Seventh Framework.

assistant: **Abstract**

We propose several new soft-matter nanotechnology-bases where the underlying principles of operation as well as the materials used are derived or inspired by biological systems. Specifically, in one aspect we wish to develop nanoscale biomimetic components, some of them with complex capacities (such as memory functions) that can perform a task in a useful device setup and that are mainly KT-driven (thermal energy-no external power source needed). A central issue relates to remote control of nanoscale soft-matter devices using microfluidics integration. Specifically, control of reactor shape, volume, connectivity, reactant concentrations etc are proposed. In another aspect, we wish to address central questions in biochemistry, biophysics and cell biology pertaining to among other things nanotube-mediated transport in cell-and cell-hybrid networks, and reaction dynamics in geometrically fluctuating nanoenvironments.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Genetic variation exposes regulators of blood cell formation in vivo in humans' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The human hematopoietic system is a paradigmatic, stem cell-maintained organ with enormous cell turnover. Hundreds of billions of new blood cells are produced each day. The process is tightly regulated, and susceptible to perturbation due to genetic variation. In this project, we will explore an innovative, population-genetic approach to find regulators of blood cell formation. Unlike traditional studies on hematopoiesis in vitro or in animal models, we will exploit natural genetic variation to identify DNA sequence variants and genes that influence blood cell formation in vivo in humans. Instead of inserting artificial mutations in mice, we will read out ripples from the experiments that nature has performed during evolution. Building on our previous work, unique population-based materials, mathematical modeling, and the latest genomics and genome editing techniques, we will:1. Develop high-resolution association data and analysis methods to find DNA sequence variants influencing human hematopoiesis, including stem- and progenitor stages. 2. Identify sequence variants and genes influencing specific stages of adult and fetal/perinatal hematopoiesis.3. Define the function, and disease associations, of identified variants and genes. Led by the applicant, the project will involve researchers at Lund University, Royal Institute of Technology and deCODE Genetics, and will be carried out in strong environments. It has been preceded by significant preparatory work. It will provide a first detailed analysis of how genetic variation influences human hematopoiesis, potentially increasing our understanding, and abilities to control, diseases marked by abnormal blood cell formation (e.g., leukemia).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Hydrogen separation from reformate produced by an on-board methanol reformerfor SPFC vehicles : development and evaluation of Metal Membrane Unit'.

assistant: **Concept**

Within the EC Joule programme the integrated development of SPFC vehicles is identified as an important approach to reducing harmful gaseous emissions into the atmosphere in the transport sector. Such systems will be basically using liquid fuels as methanol which must be reformed to obtain hydrogen to fuel the SPFC unit. During reforming always some carbon monoxide is formed which will poison the SPFC and a feasible gas clean up unit will be critical to the future SPFC vehicle technology development. Currently membrane separation with Pd/Ag membranes is considered to be the only simple and one step clean up technique to produce hydrogen with a carbon monoxide level < lOppm. The objective of the project is the development and evaluation of a prototype hydrogen separalion unit based on composite ceramic-Pd/Ag membranes. The unit is performance-effective, sizeeffective and cost-effective as gas clean up unit by means of separation of hydrogen from reformate produced by an on-board methanol reformer for 20 kW SPFC vehicles. The project concerns the development of the module as well as- the membrane material itself based on the requirements for this particular application. For a compact module design it is important to have a high membrane surface area to volume rate, a reliable sealing technique and a geometry which ensures minimal concentration polarisation. The membrane manufacturing procedure has to give low cost membranes whereas their durability (start-up/shut-down cycles) and longevity (life-time) must be sufficient. In their performance the membranes must have negligible surface catalytic effect, high flux and a good response to transient behaviour. All above mentioned issues will be investigated experimentally in order to guide the research to an advanced state of t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Nanoscience Foundries and Fine Analysis' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

We intend to study the feasibility of an European cluster of nanoscience facilities, which will consist of 3-6 Centres closely attached to a number of selected Large Scale Facilities located within Europe (synchrotron radiation sources, neutron scattering sources, high power lasers including free electron lasers and high performance computing, etc). This cluster of nanoscience facilities will enable users to conduct fine analysis experiments and modelling at the nanoscale by offering access to state-of-the-art synthesis, nanofabrication and analysis to a wide research community. Hence, by providing innovative cutting edge preparation and characterization technologies to European scientists, this delocalized institution will raise the standards of nanoscience experiments in the European Research Area and allow full exploitation of the affiliated Large Scale Facilities. The NFFA design study will develop the Emerging Proposals, named NANOSCIENCE, in synergy with the ESFRI roadmap 2006. NFFA is a structuring project for the ERA that requires to be started with support by the EC under FP7, in order to reach the maturity to be validated as a potential RI by ESFRI. The NFFA Centres for users will share a common technical platform for advanced nanofabrication and characterization of nanostructures, complemented by specialised methods for synthesis of materials, specific analysis, computational methods of simulation, according to a coordinated science plan. The NFFA design study will analyse the full spectrum of Research infrastructures relevant for nanoscience that are currently in operation OR in the preparatory phase of FP7.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Coherent Microcomb-enabled Integrated Photonic Convolution Engine for Energy-Efficient AI' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

With rapid advances of artificial intelligence (AI), conventional electronic processors are constrained by bandwidth and energy efficiency in the post-Moore era, increasingly struggle to serve large-scale, high-concurrency AI tasks within the existing von Neumann-based framework. Leveraging the inherently high bandwidth, multiple dimensions, low latency, and superior energy-efficiency of light, photonic integrated circuits (PICs), on the other hand, are promising to provide a compelling pathway for advanced AI models. To achieve this goal, the main objective of the CoMiPCE research action is to realize a fully integrated photonic convolution engine (PCE) on a scalable silicon platform by combining best‑in‑class devices and processes through hybrid and heterogeneous integration. The CoMiPCE heterogeneously integrates a diverse set of photonic devices on silicon substrates, and co-integrates them with silicon PICs through hybrid packaging to build a fully integrated PCE system, targeting remarkable throughput and energy-efficiency for AI workloads, in which the convolution operator is implemented via composite time-phase-frequency-polarization encoding based on high-speed coherent microcomb modulation. The CoMiPCE addresses the bandwidth and energy efficiency of electronic accelerators by consolidating hybrid integrated silicon nitride self-injection-locking (SIL) microcomb, programmable silicon nitride weight spectral shaping, ultrafast coherent heterogeneous lithium tantalate modulation, erbium-doped silicon nitride waveguide dispersive delay with amplification, as well as coherent silicon PIC accumulation detection, into the full-chain hybrid integrated system. Collectively, the CoMiPCE will introduce coherent SIL microcomb source, hyper-dimensional encoding, high-spee