RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Be Better Informed About Fertility. Giving voice to citizens towards improving assisted reproduction technologies for society'.

assistant: **Innovation**

Assisted Reproduction Technology (ART) plays a significant role in the reproductive health of European society and is a fast growing part of the health industry. In this context, B2-InF will seek to answer two questions: (1) How do young people perceive and think about ART? (2) How can ART clinics better align their research, services, and information with the views, concerns and expectations of citizens? By answering these questions, B2-InF aims to promote public participation in the science and provision of ART so that these become more responsive to the needs and concerns of society.  The project will be carried out in three stages. In the first stage, data is collected about perceptions and awareness of ART in young populations and the information offered by clinics to their clients. In the second stage, this data is analysed from sociocultural, legal and gender perspectives in order to detect misalignments and other weak points and to determine ways of improving the information offered by clinics. Based on this analysis, the project will produce a set of national and international recommendation guidelines. In the third stage, these guidelines along with policy briefs and other results will be disseminated to clinics, policymakers, and other key stakeholders in scientific fields, the health industry, and the general public.B2-InF proposes an integrated research methodology to be carried out in eight European countries, including several underrepresented countries of Eastern Europe: Belgium, Switzerland, Italy, Spain and Macedonia, Albania, Slovenia and Kosovo. The project is designed to work bottom-up, moving from citizens to scientists and policymakers, and will provide much-needed empirical data about the representation of ART in society, allowing for a better fi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Tools for the Large Hadron Collider - from the Lagrangian to the experimental analysis' (LHC-Tools-Phys) targeting Seventh Framework.

assistant: **Abstract**

This collaborative project is in the area of Elementary Particle Physics Phenomenology, with focus on some extensions of the Standard Model (SM) of Particle Physics and top quark physics. It brings together theoretical and experimental particle physicists. The proposed collaboration is a research programme where the applicant's expertise on the theoretical aspects of nonstandardHiggs production and the search of new physics in top quark production and decay in proton-proton collisions is matched with the expertise at the host institution as a part of the European network the applicant is building.We are especially interested in the search for the Higgs boson, the last particle (or particles) of the SM, that still remains to be experimentally discovered. The Higgs boson is potentially the key to answer the fundamental mystery of why elementary particles have mass. Its search is therefore the primary goal for CERN's Large Hadron Collider. New physics can also be hidden in the top quark, the heaviest of all known fermions. Our main goal is to contribute to a better understanding of the world of particle physics, by proposing theoretical models in the above area and developing and optimizing tools and data analysis techniques to experimentally detect their signatures.The expertise and skills of the the parties in this proposed collaboration (where not only the host institution takes part but also other institutions in Portugal and in the UK) match and complement each other extremely well. Exploring this synergy will produce a very fruitful collaboration, mutually advantageous to both parties. This application is ideally timed, as the data taking phase of ATLAS and the LHC has started at a centre-of-mass energy of 7 TeV and it will resume operation in 2013 with the planned 1
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Biogenic volatile organic compound (bvoc) emission of european forests under future co2 levels: influence on compound composition and source strength' (FUTURE-VOC).

assistant: **Innovation**

Problems to be solvedThe role of forests in preserving the environment is undeniable and ranges from ecological buffer for nutrient and CO2 cycles, to being a key controlling factor of the hydrological cycle, and to being source of biodiversity stabilising ecosystems. Forests are also a major source of volatile organic compounds (VOC). Plant species differ in VOC emission and emissions are strongly co-determined by concurrent climate. BiogenicVOC are formed and emitted with estimated 1.1 Pg C per year on global scale. Although this emission accounts for approximately 2% of the total C-exchange of 69 Pg between the biota and the atmosphere, it has not been considered in global C-cycling so far. Biogenic VOC play also an important role in the oxidation processes of the lower troposphere leading to high ozone and photochemical smog during periods of high radiation and temperature at low wind speeds when BVOC emissions are usually high. Therefore, there is a pressing need to understand the effect of plant diversity and the effect of global change factors such as elevated CO2 on the source strength and pattern of VOC emission of European forests for establishing effective photooxidant reduction strategies and for correctly assessing the carbon sinks in the biosphere.Scientific objectives and approach:To correctly assess the impact of elevated CO2 on plant ecophysiology, and hence VOC emission on European scale both long term fumigation experiments in the natural environment and mechanistic studies in controlled environment chambers are necessary. The projects benefits from already existing infrastructure and from databases available for the field sites in Switzerland (Swiss canopy crane project SSC near Basel) and Italy (CO2 springs in Tuscany) and from controlled environmen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Optimising forest operations for sustainable forest management and high-value applications' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Forestry is a potential pathway to strengthening European competitiveness, reducing dependence on non-renewable, unsustainable resources, enhancing the circular bioeconomy, and understanding the bioeconomy’s ecological boundaries. Europe’s forests and their value chains, however, face diverse challenges, including increasing global wood demand, biodiversity loss, and increasing biotic and abiotic threats to forest health and economic revenue caused by climate change. OptiForValue’s ultimate goal is to foster transition to more sustainable and resilient forest-based value chains, by using a unique, interconnected modelling framework involving strong participative engagement and novel scientific approaches, including early warning indicators of biotic and abiotic risks, adaptive forest management strategies, remote sensing and artificial intelligence for agile forest operations, and integrated value-chain optimisation and life cycle assessments. The expected outcomes include increased value addition, competitiveness, sustainability, and resilience of European forest-based value chains, particularly in regions already or forecast to be impacted by climate change over the coming decades. OptiForValue will accelerate this transition by enhancing the sustainability, resilience, and profitability of regional value chains in Central European, Mediterranean and boreal, via case studies in Austria, Spain, Sweden, Finland. Significant long-term impacts are expected to be achieved, including a 10% reduction in wood damage, with a subsequent increase in wood harvesting (€240 M annually), 3% value addition from better quality control (€350 M annually), 5% increase in the forestry workforce in areas affected by climate change, and 5–10% reduction in fossil fuel consumption and greenho
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'The Langlands Correspondence' in the context of a Horizon Europe call.

assistant: **Objectives**

R. Langlands conjectured the existence of a correspondence between automorphic spectrums of Hecke algebras and representations of Galois groups of global fields. The existence of such correspondence is one of the main conjectures in mathematics. Even if not known in full generality it leads to proofs of Ferma and Sato-Tate conjectures. This project is on three aspects of the Langlands correspondence. The first part of this project is a description of the spectrum of Hecke algebras on the space generated by pseudo Eisenstein series of cuspidal automorphic forms of Levi subgroups. In the simplest non-trivial case, the precise description is a conjecture of Langlands. This conjecture is proven in my work with A. Okounkov, by an unexpected topological interpretation. I expect this approach to work in a number of other cases. The second part of this project is an extension of the Langlands correspondence to a completely new area of fields of rational functions on curves over local fields. This extension of the Langlands correspondence to a new area could lead to new interplays between Representation Theory and Number Theory.The third part of the project is on a categorification of the Langlands correspondence necessary for establishing the strong form of this correspondence.


**Keywords:** Langlands, Representations, Categorification, G-equivariant bordism, local fields, automorphic forms, 1, 2- forms, Hecke correspondence, Hecke operators, categorical trace, symmetric infinity categories, nilpotent singular support, Eisenstein series, the Springer stack, Opers, reductive group, global and local fields, dual group, curves, global differential operators on the stack of $G$-bundles, cohomologically proper quotient stack
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Environmentally benign, energy and structural materials saving solid lubricants for machine- building industry' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The absence of technologies for sufficient (2-3 times) improvement of material swear resistance under severe operation conditions limits a reliability of modern machines and mechanisms. The main Proposal objective is the development of environmentally benign innovative technology of synthesis of solid lubricants allowing to: increase in 2-3 times the durability of slipper pad bearings (rolling mills) and bushings (large scale presses and metal forming machines); increase in times the durability of rolling tools and dies for cold metal forming; increase in 2-3 times the durability of conic-roll bearings (cars and industrial vehicles);decrease of oil lubricants consumption of 720 000 tonnes per year and greases consumption of 10 000 tonnes per year; decrease in 2 times of carcinogens components in working environment in machine building and steel industry; decrease of 12% electricity consumption of large scale presses and rolling mills.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'MERGING SUSTAINABLE AND DIGITAL CHEMICAL TECHNOLOGIES FOR THE DEVELOPMENT OF GREENER-BY-DESIGN PHARMACEUTICALS' to be submitted under Horizon Europe.

assistant: **Abstract**

Safe- and green-by-design are pre-market design approaches whereby the objectives of minimizing the use of hazardous chemicals, reducing greenhouse gas emissions, and fostering the reuse and recycling of materials in a circular economy are built into product design. SUSPHARMA fits the European need for sustainable development in modern industry and will develop during the action greener routes to prepare molecules, such as therapeutics and diagnostics.The breakthrough innovation will involve:- use of renewable (bio-based) carbon for the building block of scaffolds and motifs for drug synthesis;- cleaner synthetic methodologies for C-X bond formation (that is, C-H functionalization to obtain C-C, C-F, and C-I bond formation);- development of new benchtop continuous purification methods, to remove impurity and recycle synthetic solvents;- integration of digitalization methods.- LCA and TEA assessment for sensibly reducing the impact of pharmaceutical production.The project will thus benefit from an interdisciplinary domain, involving:- recent advances in biomass conversion for drug synthesis;- new developments in heterogeneous catalysis;- cutting-edge flow chemistry technologies (including synthesis and purification);- automation and machine learning.To address the challenge of green and digital transition and proper supply of health technologies and products, SUSPHARMA will focus on research and innovation activities that aim at integrating five breakthrough concepts: CAT-to-PHARMA, WASTE-to-PHARMA, FLOW-to-PHARMA, PUR-to-PHARMA, and DIGITAL to PHARMA. This will deliver results that are directed to pharmaceutical industries, researchers, and innovators, prompting them to develop and produce greener pharmaceuticals that are either greener by design, intrinsically less har
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Peptide-drug conjugates for weight loss maintenance' in the context of a Horizon Europe call.

assistant: **Objectives**

The worldwide rise in obesity rates is causing significant harm to human health. While effective weight loss therapies are emerging, the challenge of maintaining weight loss remains unresolved. With this project, we will leverage expertise in drug development to engineer novel peptide-drug conjugates designed to obstruct homeostatic weight regain in a cell specific fashion. In the food deprived state, a subset of hunger promoting neurons undergo structural changes that increases excitability and thus drives homeostatic weight regain. Capitalizing on our knowledge of G protein-coupled receptors (GPCRs) expressed in hypothalamic cell populations we will develop GPCR-targeting peptide-drug conjugates specifically designed to obstruct weight recidivism. To evaluate this drug-targeting approach, neurobiological methods including fiber photometry will be employed to confirm target engagement. Preclinical models are used to investigate the translational potential for treatment of weight loss maintenance following dietary and pharmacological weight loss interventions. The molecular mechanisms of action and receptor-target selectivity of the conjugates will be determined using loss-of-function mouse models. Pharmacokinetic properties of lead candidates will be optimized by incorporating chemical half-life extenders. This bridging between medicinal chemistry, neuroscience and pharmacology will give rise to new multimodal molecules targeting homeostatic weight regain mechanisms to address a vastly growing unmet medical need for weight loss maintenance pharmacotherapies.


**Keywords:** Obesity, weight loss, pharmacology, weight loss maintenance, body weight, appetite, hunger, satiety, hypothalamus, AgRP, peptide-drug conjugates, drug design, medicinal chemistry, peptide chemistry,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Allergenicity Prediction Toolbox for novel foods'.

assistant: **Innovation**

Introduction of novel foods, such as insects, will strongly contribute to the security and sustainability of our food supply. However, these novels foods need to be safe (EU regulation 2015/2283). Allergenicity assessment is an essential part of the safety assessment of novel foods. Unfortunately, current methods to assess de novo allergenicity lack predictive power and are not validated. Consequently, food producers and risk assessors struggle with allergenicity assessment, slowing down the introduction of novel foods in our food supply. Enabling the safe introduction of novel foods, while protecting humans from unacceptable food allergy risks, calls for a multidisciplinary approach. The ALLPreT consortium is a highly multidisciplinary group of experts from universities, research institutes, hospitals, patient organisations and industry arising from the EU COST Action ImpARAS (Improved Allergenicity Risk Assessment Strategy). This puts them in an ideal position to consolidate their previous collaboration and set up an innovative doctoral training network in this area. The overall goal of ALLPreT is to train the next generation of scientists who can tackle the shortcomings in the current food allergy assessment of novel food products. ALLPreT will train early stage researchers (ESRs) in the core aspects of food allergy risk assessment, immunology, protein chemistry, bioinformatics, in vitro/in vivo/in silico model development and complementary “soft” skills to deliver well educated young scientists, with a unique position within the EU labour market. The ESRs will explore the new field of research on de novo sensitisation by novel foods and develop a toolbox of in vitro/in vivo/in silico allergenicity prediction tools that are scientifically sound, validated and easily
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Development of an environmentally-friendly protection for sweet pepper and strawberry' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

Pesticides used in agriculture to maintain healthy crops have many side effects on environment and health. One of the objectives of the CAP reform is to reduce the use of pesticides in agriculture and encourage biological control. The biological control consists in the utilisation of specific parasites and their predators in order to control the population of major pests. The present project will concentrate on strawberry and sweet pepper that are exported on a large scale every winter from producers in the Mediterranean basin to consumers in North Western Europe. They are grown under protection, i.e. greenhouses or screen houses, under intensive regime of agrochemicals. The aim is to develop new biological management strategy for pest control and improve procedures for natural enemies' production and delivery in the culture of strawberry and sweet pepper. We plan to: -develop a new natural enemy for bio control of the sweet potato whitefly-improve the decision-making tools to control the western flower thistle expected results are to reduce the use of pesticides, preserve the environment and assurance to the consumer regarding t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'INTEGRATE - Interdisciplinary Network for Training, Education, and Growing Research into Applications of and Therapeutic Expertise around Psychedelics' (INTEGRATE) under Horizon Europe.

assistant: **Objectives**

Late-stage clinical trials show that psychedelic therapy (PT) has the potential to revolutionize mental disorder treatments, answering a huge and increasing unmet need. INTEGRATE is a multidisciplinary, multi-sectoral Doctoral Network (DN) for training and educating future leaders/experts in implementation of PT in society and healthcare. Four key challenges are identified: 1) The mechanisms of action of PT remain elusive, 2) Lack of clinical gold standards, 3)  Legal, financial, and regulatory obstacles for PT access, and 4) Hype, hope, and ethical challenges. Through interdisciplinary research, training, and collaboration, INTEGRATE aims to advance psychedelic science, optimize treatment protocols, and address ethical and regulatory challenges to improve mental healthcare. It addresses the urgent need for well-trained experts to navigate the complex landscape of PT in healthcare. The project will train 16 Doctoral Candidates (DCs) to become T-shaped professionals, equipped with deep disciplinary knowledge and broad interdisciplinary skills. Through collaborative research, innovative training, and strategic secondments, INTEGRATE will tackle the key challenges in PT research with matching research and innovation objectives. The network brings together leading academic institutions, industry partners, and non-profit organizations across Europe, fostering a collaborative environment for advancing psychedelic science and improving mental healthcare.


**Keywords:** Psychedelic therapy