RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Rare genetic skin disease: advancing diagnosis, management and awareness through a European network' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

Genetic skin diseases comprise almost 300 rare but often severe and even life-threatening diseases and syndromes. Despite recent identification of causative genes in a number of these disorders, the molecular bases of several others are still unknown, and often the function of the identified disease-gene products remains an unsolved mystery. In addition, disease number and rarity impair proper management, and no curative therapy is available. By bringing together clinicians, researchers and patient associations, GENESKIN aims to generate accessible knowledge and improve health care service structures for affected people. The focus is on five major disease categories: epithelial adhesion disorders, keratinization disorders, ectodermal dysplasias, connective tissue diseases, DNA repair disorders. For each group, a clinical and laboratory network will generate and disseminate: 1) a list of reference centers with services offered, 2) diagnostic questionnaires/protocols 3) gene cards, mutation database, diagnostic reagent lists, and ongoing clinical trial list. The research topics to be co-ordinated in GENESKIN deal with: i) improved early post-natal and pre-natal diagnosis by novel immunohistochemical/biochemical and molecular tests, ii) identification of new genes involved in genetic skin diseases by collecting a sizable number of biological samples iii) definition of genotype-phenotype correlation and characterisation of newly identified gene product functions by creation of a sample Databank. Knowledge dissemination and improved management will also be insured through the organisation of involved personnel training. Finally, pan-European communication among patients' organisations, ethic committees, physicians and scientist will be promoted. The information regarding cli
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Emulsion-templated structuring of liquid oil for future development of saturated fat-free food products'.

assistant: **Innovation**

The dangers of consuming high amounts of saturated fats have been well-documented in the past couple of decades. Surprisingly, even after much negative publicity and consumer concerns, the replacement of saturated fats in manufactured food products has been very slow. Some promising alternative systems have been identified as the future of oil structuring without the presence of saturated fats. However, their potential for food applications are yet to be proven in actual product conditions. Emulsions are the most common colloidal systems that forms basis of many of the edible food products, hence, structuring approaches based on the use of emulsions as the templates can be considered ideal for food application provided we restrict ourselves to the use of food-grade materials. The proposed research is an ambitious project to enhance the fundamental understanding of the complex physico-chemical and colloidal aspects that accompany the process of oil structuring. The specific objectives of the proposed research is to focus on the use of food-grade materials such as proteins and polysaccharides to generate oil continuous and water continuous emulsions and further use these emulsions as templates to change liquid oil into soft, elastic gel-like systems.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'TASK-FORCE IN EUROPE FOR DRUG DEVELOPMENT FOR THE YOUNG' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

The knowledge generated by the sequencing of the human genome will enable the development of more effective strategies for preventing, diagnosing and treating human diseases, and consequently decrease morbidity and mortality. One can therefore anticipate that children should benefit from advances of the genome era.Application of advances in genomics, biotechnology and therapeutics to provide children with more efficacious and safer medicines will require the development of a new research matrix that integrates scientific domains, assesses impact of findings and implements policies. Furthermore, any attempt to integrate genetic information into medical practice ought to consider human development and maturation, from the prenatal period through adolescence.TEDDY project is aimed at optimising the paediatric use of current drugs and promoting the development of new drugs, by incorporating pharmacogenetic applications and implementing guidance/tools to perform paediatric research. Special attention will be paid to variability in response, particularly, the role of gender factors and time-dependencies associated with the development from prenatal period to adolescence. A framework will be developed to characterise adverse drug reactions and optimise dosing regimens, including research projects on pharmacogenetic variants. Harmonised databases and guidelines will be created for marketed medicines. Training programmes on ethics, scientific and clinical skills will be set up to increase research capacity and promote social awareness.The proposed network will include stakeholders in drug development and paediatric clinical practice. European academics, scientists, healthcare specialists and ethics experts will work together with pharmaceutical companies, regulatory agencies and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Feasibility Study for Fleximodo – Smart IoT Sensors with Software for Parking Management'.

assistant: **Concept**

Outdated parking management leads to a range of economic, environmental and infrastructural inefficiencies which affect the quality of life in cities. Adoption of smart parking solutions can optimize the use of existing infrastructure and resources, leading to a better service for end-users and optimized operational costs for parking providers. However, existing solutions have limitations that range from inaccurate measurements, weak battery life, sustainability (lack of control of deployed infrastructure) and its reliance on expensive proprietary protocols with no chance for massive deployment that is possible via cutting edge LPWAN of existing cellular networks with nationwide presence.Furthermore, the smart parking market is growing fast: European market is expected to grow by 9.6% CAGR during 2018-2024, the North American will grow by 18,4% CAGR in the next 3 years. Therefore, GOSPACE utilized its expertise in space research and IoT-networks to develop Fleximodo, a superior IoT parking solution. As a result, compared to competitors, Fleximodo is the only solution with manufacturing and connectivity standards (LPWAN) expected from components used for space satellites. Its detection technology relies on 3-axis magnetic field and unique corrective algorithm detecting occupancy with a nearly 100% success rate. GOSPACE parking detectors are compatible with all major IoT networks and provide seamless firmware updating. The authorization and authentication features, applicable in multiple use-cases, further position GOSPACE to fill the gap in the on-street smart parking market. Lastly, each detector is shielded in a special case which is extremely durable & resistant to any violation and extreme conditions.The main objectives of Phase 1 of SME Instrument are to develop an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'EUROPEAN UNION NETWORK for INVESTIGATION OF DENDRITIC CELL IMMUNOTHERAPY FOR INDUCTION of ANTI-VIRAL AND ANTI-TUMOR IMMUNITY AND TRANSPLANTATION tolerance' under Fourth Framework.

assistant: **Concept**

The proposed Research Network comprises ten Partners who will collaborate in the seven defined Tasks over three years (six periods) for training of long-term goal is to use DC for immunotherapy of human diseases. The eleven postdoctoral Researchers. Ten Researchers will work for three research objectives of this joint research project address the main issues periods with the principal host Partner, and for the remainder with up to that need to be resolved before this goal can be implemented at the three different Partners engaged in similar Tasks. The eleventh Researcher Community level. Seven, interrelated Tasks have been identified. Molecular and cellular techniques will be used to define, for murine and human DC: will be engaged in Network Tasks, working between Partners and liaising lineage and stage-specific genes and proteins (Task 1); conditions for with the Network Coordinator. growth and purification of subsets with specific properties (Task 2); antigen receptors and processing compartments (Task 3); and costimulatory molecules for regulation of T cell activation (Task 4). This knowledge will then be applied in vivo, in both experimental and/or clinical settings, for induction of anti-viral immunity (Task 5), anti-tumor immunity (Task 6) and transplantation tolerance (Task 7).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Alternative splicing in developmental control and stress response in Arabidopsis thaliana' in the context of a Sixth Framework call.

assistant: **Objectives**

Alternative splicing (AS) has recently emerged as one of the most important mechanisms for generating proteome diversity and regulating gene expression. It is becoming clear that the majority of human genes encode transcripts that undergo AS, greatly enhancing the coding potential of the genome. Very few examples of alternatively spliced transcripts have been reported in plants and still fewer are known to generate functionally distinct proteins. However, the recent explosive growth of available expressed sequence data and its alignment with genomic sequences indicates that AS plays a far more important role in plants than previously thought, and further work is necessary to uncover the significance and regulation of this process.The unique developmental plasticity and stress tolerance developed by plants as a result of their sessile growth habit suggests that they offer exceptional opportunities to reveal AS mechanisms, which are likely to play a key role in the adaptation of plants to changes in their environment. This project will investigate both the biological relevance of AS in plant development and stress responses and the regulatory mechanisms of plant pre-mRNA splicing about which virtually nothing is known.The functional significance of different splice variants of specific development- and stress-associated genes will be examined using reverse genetic approaches in Arabidopsis thaliana. Moreover, the function of individual serine/arginine-rich (SR) proteins, which are established key players in mammalian AS, and their stress-specific expression patterns will be analysed. A computational approach will also be employed to identify plant splicing enhancercis-acting elements (ESEs) recognized by SR proteins. This work deals with an exciting area of plant biology
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Thematic network in the field of baking technology and baking equipment.' in the context of a Fifth Framework call.

assistant: **Objectives**

This project will co-ordinate research to meet the needs of the bakery industry and improve processing efficiency. The network will also maintain a training programme on a range of specific topics that are forcing reform and modernisation in the foods industry. In order to disseminate and exploit the network activities and results, a web page will be set up with public access. The European bakery industry is not operating as efficiently or cost effectively as possible due to poor dissemination of novel technologies and processes across the industry sectors. This network will establish better communication and co-operation between all sectors within the bakery industry to lead to a definition of the requirements of modern baking technology for applications, protocol and management philosophy. Steps will be taken to address specific needs in the industry brought about by environmental and safety legislation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Simulation tool development for a composite manufacturing process default prediction integrated into a quality control system'.

assistant: **Concept**

Resin Transfer Moulding (RTM) involves moderate pressure resin injection of a dry preform placed in sealed rigid tooling. Fast and effective processing requires correct placement of the reinforcement to avoid defects and potential race tracking, appropriate selection of inlet and outlet locations, and careful control of flow speeds to minimise porosity and dry regions; furthermore, suitable cure conditions are needed to avoid under-cure, or exothermic effects that generate excessive residual stresses and final part distortions. Today, finite element simulation is regularly used to design injection processes and cure. However, purely predictive simulation suffers from issues related to uncertainty and variability in material state and numerous process variables. Online monitoring of resin flow in tests and stochastic simulations to understand effects of material and model variability on flow processes could be two methods to enhance fidelity of numerical simulation models.The proposed project integrates three approaches to provide a unified integrated simulation tool combining predictive modelling, variability propagation and process monitoring. Input utilises material data and models to be developed with physical resin sensor results, from which process outcomes, conditional on material and process variables, are determined. The proposed work develops this concept for the three stages of RTM processing; namely, preforming, injection and cure. The overall concept will be implemented on a pilot RTM line and then transferred to the Topic Manager’s manufacturing site, where it will be used for trials.The project combines two universities with specialist knowledge in fabric mechanical and permeability modelling, resin test and modelling and numerical simulation of RTM proces
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'COdesign urban REalm & dynamic Spaces management for cognitive & socially connected cities', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Cities are under increasing pressure from rapid urbanization, rising mobility and energy demands, and the need for climate-neutral solutions to efficiently design and manage urban space. COREspaces will transform urban spaces by addressing critical challenges related to space scarcity, mobility and energy efficiency and sustainability. It integrates advanced digital tools (e.g. AI-assisted planning, Digital Twins) to enable cities to manage urban space, optimize mobility infrastructure, increase energy efficiency and enhance urban resilience. The project’s emphasis on citizens’ engagement and inclusive decision-making, leading to equitable and liveable urban environments while contributing to climate-neutral urban spaces, aligning with EU sustainability goals. Based on vast pre-existing mobility and energy innovations specialized in citizens driven co-creation and urban space design, the project introduces COREInnovations, a set of adaptable digital and physical tools that integrate AI, DTs, and participatory planning to optimize urban space use and support climate neutrality. Real-world demonstrations hosted in Living Lab from 9 European cities will pave the way towards data-driven and human-centric urban transformation.The project fosters cross-sectorial collaboration between cities, public authorities, citizens, academy and industry partners to ensure evidence-based decision-making for sustainable urban transitions, aligned with the EU Green Deal and Climate Neutrality goals of cities while supporting the objectives of the Work Programme.  The project addresses challenges by developing practical methodologies and robust solutions and governance frameworks to speed up decision making; innovative strategies for urban space reallocation and dynamic curbside management;
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'OBSERVATION OF ECOSYSTEM CHANGES FOR ACTION' under Horizon Europe.

assistant: **Concept**

The objective and key ambition of OBSGESSION is to monitor and predict biodiversity change and its direct and indirect drivers in terrestrial and freshwater ecosystems through the integration of state-of-the-art multi-sensor Earth Observation (EO) data, innovative in-situ (including citizen science) data, and products, together with next-generation ecological models that account for uncertainty. This aim goes well beyond the current state-of-the-art in combining the various data sources, modern modelling and uncertainty estimation. The methodological principles include firm anchoring into science and policy needs, true interdisciplinarity between terrestrial and freshwater as well as EO and ecosystem modelling disciplines, and FAIR and open science practices, including sharing of research outputs with both the scientific community and the civil society, to study how biodiversity across terrestrial and freshwater domains is changing and the processes and needed innovations leading to efficient science-based solutions towards observation of ecosystem changes for action.


**Keywords:** Biodiversity conservation, Earth and related environmental sciences, Environment, Freshwater ecosystems
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project '“E-static Soft Sensors: A study on applying industrial manufacturing techniques to develop self-powered triboelectric textile sensors for high-accuracy activity recognition in smart homes”' (2021-2027), addressing dissemination and exploitation.

assistant: **Impact**

E-static soft sensors is an investigation into manufacturing self-powered triboelectric textile sensors with regular materials (for e.g. wool, polyester and conductive yarns) for high-accuracy activity recognition in smart home applications. Triboelectricity is generated when materials such as human skin and synthetic fabrics repeatedly rub together. This form of electricity is considered annoying or can even be dangerous. However, when handled safely it can provide unique insights into our everyday interactions with textiles and present an environmentally-friendly solution for sensing different kinds of activities for smart home applications, such as fall detection for elderly care, assistance in indoor navigation or sports tracking and game design.Recent advancements in textile-based triboelectric nano generators(tTENG) have highlighted the rich potential of using this energy for powering low-power devices. However, their sensing capabilities remain limited to a single repetitive movement. Additionally, the current work in tTENG present one-off prototypes and are not at a stage where they can be manufactured on a larger scale.With an aim to tackle these challenges, the project develops an approach for constructing high-performance self-powered triboelectric sensors without the need for specialised materials using industrial production techniques of weaving, tufting, and embroidery. These sensors will be evaluated and optimised for high accuracy self-powered activity and gesture recognition by applying advanced textile construction knowledge to optimise the structures and using AI models to fine tune the sensing analysis. Additionally, their tactile and interactive properties would be evaluated in order to improve their suitability and acceptance of embedding them in e