RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Reconstruction Algorithms for Biological Networks' (BIONETRECON) targeting Seventh Framework.

assistant: **Abstract**

We propose to develop reconstruction algorithms forbiological networks. Biological networks such as Phylogenies andPedigrees are key components in the mathematical analysis of evolutionand population genetics. Cellular and Metabolic networks areextensively studied in molecular genetics. We will develop algorithmsfor reconstruction of networks from data and study cases wherenetworks cannot be reconstructed. Our approach is rigorous: we specifymodels exactly and give explicit running time, sampling complexity and correctness guarantees thus laying foundations for more applied work in theseareas.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'European Virtual Environment for Research - Earth Science Themes' to be submitted under Horizon 2020.

assistant: **Abstract**

The EVER-EST project will enhance Research and Capacity Building in the Earth Science (ES) domain,  by providing a generic Service Oriented-based Architecture Virtual Research Environment (VRE) tailored to the needs of the ES community. The full range of both generic and ES data management specific services provided by EVER-EST will facilitate the dynamic approach to collaborative working and research. Scientist will be able to discover, access, process, share and interoperate heterogeneous data, algorithms, results and experiences within and across their communities, including those in domains beyond Earth Science. Data providers will be able to monitor users experience and collect feedback through the VRE, improving their capacity to adapt to end-user needs offering solutions to unlock scientist potentials and creativity. EVER-EST e-infrastructure will be validated by four Virtual Research Communities (VRC) covering different multidisciplinary working ES domains: ranging from Sea Monitoring, to Natural Hazards (floods, weather, wildfires), Land Monitoring and Risk Management (volcanoes and seismic). Each of these VRC will use the VRE according to its own specific requirements for data, software, best practices and community engagement. The VRE will leverage on the results of several FP7 projects which have produced state-of-the-art technologies for scientific data management and curation. Such capabilities will be enriched during the EVER-EST project using the output of a second group of FP7 initiatives providing models, techniques and tools for the preservation of scientific methods and their implementation in computational forms such as scientific workflows. EVER-EST will implement solutions for data publication, citation and trust. EVER-EST will provide the means t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Turning non-recyclable aluminum waste into metal foams with multiple applications' to be submitted under Horizon 2020.

assistant: **Abstract**

Aluminum is becoming even more important raw material used in various industries and applications (e.g. lightweight electric vehicles). Over 50% of it produced out of collected waste such as aluminium scrap saving natural resources (bauxites) and energy. Since it requires only 5% of the energy required to produce the primary aluminum. Unfortunately, there is still large amount of aluminum waste (app 5.343 million tons p.a.)  going to landfill each year which is neither cost efficient nor neutral to our environment. Createc developed a breaking technology in the form of a recycling process which allows to bring the non-recyclable aluminum waste back into the market thus closing the production cycle. We show how to produce an aluminum foam to make aluminum foam panels. The panels are in the interest of vehicle parts manufacturers, designers, and architects. The foam panels are perfect as energy or noise absorbers and at the same time lightweight with an attractive look. Our technology is environmentally friendly, meaning that we eliminate any chemicals in the production process and we use only 1% of the energy required to produce the primary aluminum. Our panels will be offered in B2B model as two product types: 1) the standard of- the-shelf panels for e.g. architects available at retail shops, 2) as highly customized and specialized products for the hi-tech industry (automotive, aerospace).  The aluminum foam market is quickly growing at 7% CAGR and is worth at least €200M in the automotive and decorative markets. The market demand for our foams has been initially confirmed with big manufacturers of car parts, potential customers for energy/noise absorbing panels and architects. Within the Phase 1 project we aim at extending our knowledge of the business environment in o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'IOD service mISsions PortfoLio' (IODISPlay) targeting Horizon 2020.

assistant: **Abstract**

Current IOD/IOV possibilities are restricted to either the identification of carriers of opportunity or to dedicated missions where a satellite is designed as a compromise among the needs of a number of identified technologies to be demonstrated in orbit.In order to actually bring a significant added value in the identification of a portfolio of European IOD/IOV solutions, the consortium believes that a clear, independent and extensive assessment exercise must be carried out of the current European IOD/IOV situation, both in terms of needs (technologies in need of flight heritage) and capabilities (carriers and launchers). Moreover, in selecting which mission concepts to co-finance within H2020 among all COMPET-5 generated ones, we believe that the commission should be in position to select (based on the output of this activity) the ones that have the real potential of maturing into a recurrent IOD/IOV service.In this view, IODISPLay has the following objectives:• To identify a portfolio of IOD/IOV missions and concepts achievable and affordable within H2020 timeframe and to down-select a number of optimum IOD/IOV missions and to carry out a preliminary design of those missions, including programmatic aspects• To provide a specific methodology for mission portfolio identification, through an IOD/IOV missionization tool which can intelligently analyze a database of carriers and technologies in order to consistently provide a number of IOD/IOV missionsThe IODISPLay consortium of GMV, VVA, INTA and GAUSS combines the experience in mission studies and IOD with proven flight-record backed system engineering as well as deep knowledge of launcher segment, including a business exploitation facet. The consortium composition and nature guarantees objective independence in the tre
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Exploring new technologies for the next generation pulse tube cryocooler below 2K' to be submitted under Horizon 2020.

assistant: **Abstract**

With the development of physics and new technologies, it has proposed some new challenges for the traditional 4K pulse tube cryocooler (PTC). The next generation 4K PTC with smaller size, lower power consumption, higher efficiency and lower temperature is anticipated. This project aims to develop a new type 2K PTC with 3He-4He mixtures as working fluid. This work will not only explore its internal new cooling mechanism, but also break up the limit temperature of Stirling type PTC, which would extend the application areas for the next generation PTC, especially for the areas of space exploration and quantum computing.The proposed new type PTC will use the unique properties of 3He–4He mixtures to improve its performance. To implement this project, it need first to clarify the underlying working mechanism of mixture gas in PTC, which will provide theoretical foundations for designing this kind of PTC. And then to develop experimental system to valid theoretical model and explore its limit temperature. Specifically, the Fellow will (a) develop a full temperature range thermal-properties database of 3He-4He mixtures, to be used to CFD simulation; (b) develop a theoretical and simulation model to clarify the mechanism of cooling effect in this PTC; (c) experimental verification the numerical results and optimization of its performance. The new results of this project will help us to shape the emerging research area of next generation PTC. The Fellow is currently at forefront of international advances in 4K PTC. With support from the hosting institutions LNE/Cnam, a timely award of the Marie Skłodowska-Curie Fellowship will provide the applicant the necessary resources and access to expertise to make rapid progress in this emerging research area and become an independent resea
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Development of a system to control theair flow and the conditions of the fabrics inside stenters and backcoating machines' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Background Drying, setting and back-coating operations represent crucial stages in the production of textile floor coverings. These processes have a major influence on the quality of the final product and on the production costs. However, for the purposes of objective reproducible machine adjustment and obtaining optimum energy economy and environmentally friendly process control, there has been no data due to the fact that no suitable measuring system exists for obtaining this information up to now . Objectives The objective of this project is to develop a method of measurement which is necessary for production and quality assurance. The aim of the system is the on line (concomitant with the product) determination and evaluation of the flow status within the machine and the condition of the fabric during production (nature and direction of flow, temperature, humidity). The data obtained continuously in this way across the width and along the length of the machines are a prerequisite for reproducible machine operation are the basis for optimisation of the entire process in question. The measuring system will be used in stenters and dryers with a range of production speed up to 30 m/sec, working width up to 6 meters and temperatures up to 200 C. Work programme To learn about the basic air flow effects inside the machinery a mobile premeasuring system will be developed in cooperation of both research partners to evaluate the in time working machinery under realistic conditions. With the help of all consortium members a job profile will be evaluated so that the measurement system will fit on the different kinds of machinery. Following a theoretical calculation of the probes and the probe development itself can be done. An extensive test programme for the evaluation of the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Targeting the ""untargetable"" by merging biological and chemical compound libraries""' (TARGET) under Horizon 2020.

assistant: **Objectives**

Genome sequencing combined with powerful new research technologies has greatly expanded the number of potential drug targets, offering enormous opportunities to address unmet medical needs. However, for proteins with flat, featureless surfaces or for protein-protein interactions, it has been difficult to impossible to generate ligands based on classical small molecules, hindering their evaluation as targets and the development of drugs.Herein, we propose a new method and its application for targeting the so-called ""undruggable"" proteins by tapping into a new chemical space, generated by ""merging"" biological and chemical compound libraries. In brief, millions of short cyclic peptides (46 amino acids) genetically encoded by phage display (generated with methods we established previously) will be expanded by combinatorially attaching via lateral groups > 1000 different chemical fragments in separate wells of microwell plates. We will develop a strategy that combines the elements of i) automation, ii) liquid transfer by acoustic dispensing, iii) single-round phage display panning, iv) ""phage PCR"" and a primer coding strategy, v) next-generation sequencing (NGS) and vi) computational sequence analysis to perform phage display selections with a library comprising > 1000 non-natural building blocks.We expect that this technology will deliver ligands to challenging proteins and facilitate their evaluation as drug targets. The ligands are kept small on purpose, below one kDa, and the polarity is limited so that they are more likely to be cell permeable and so they may directly serve as leads for the generation of oral drugs.""


**Keywords:** drug development, undruggable targets, combinatorial libraries, cyclic peptides, phage display, high-throughput screening, macrocycl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Decoding Monocyte Metabolism in Myocardial Infarction: A Time-Sensitive Approach to Limiting Heart Failure'.

assistant: **Concept**

Cardiovascular diseases (CVD), particularly myocardial infarction (MI), are partly driven by chronic inflammation, in which myeloid cells, such as monocytes and macrophages, play a central role. This project aims to elucidate the metabolic mechanisms regulating monocyte function and their impact on post-MI recovery. Emerging evidence suggests that the metabolic state of myeloid progenitor cells and their descendants critically influences their pro- or anti-inflammatory functions. While glycolysis dominates early after MI, fatty acid oxidation takes over later stages, indicating that metabolic reprogramming is essential for monocyte and macrophage function.In this project, we will investigate the metabolic signatures of monocytes at different time points post-MI using a preclinical mouse model and the human HIBISCUS STEMI cohort. We aim to identify key metabolic pathways that can be targeted to modulate inflammation by employing single-cell RNA sequencing and single-cell metabolic assays. In mouse models, we will further test the effects of transiently inhibiting glycolysis or fatty acid oxidation in monocytes, using genetically modified mice, to determine whether this approach improves cardiac function and limits heart failure.Additionally, the fellowship will provide essential soft skills training in project management, mentoring, and grant writing, which are crucial for my transition to an independent research position. These skills will enhance my leadership abilities and prepare me for future academic and industrial opportunities. This research will provide new insights into the role of metabolism in myelopoiesis and inflammation and could lead to novel therapeutic strategies to improve outcomes in CVD patients.


**Keywords:** Myocardial infarction, heart failure,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Development of advenced hybrid heat pipe receivers in dish/stirling systems for decentralized power production' in the context of a Fourth Framework call.

assistant: **Objectives**

Project Objectives The objective of the project is to contribute to a commercialization of the dish Stirling technology that can provide the decentralized power demand of small communities in Mediterranean countries utilizing concentrated solar radiation. Key component is the solar receiver which will have to be improved with respect to lifetime and economy, and will have to be hybridized, in order to increase the availability of electric power supply. Therefore, the following three goals are pursued: To develop heat pipe receivers with specially adapted combustion systems (natural, biogas) for a possible 24 h / d operation, to considerably decrease the investment costs by a new manufacturing method for the wick structure of the heat pipes and to demonstrate technical maturity by a one year's routine operation in two dish Stirling systems. Technical Approach A low emission, high efficiency and high density combustion system, based on proved burners used in small co-generation units, will be developed. This work includes heat transfer calculations for the development of a new preheater, investigations of appropriate high temperature materials, the adaption of the air and fuel systems and finally the construction of two burners. Parallel to the construction of two heat pipe receivers with conventional wick structure, a new production method using the high frequency plasma spraying (HF-PS) technique will be developed. After investigating the influence of HF-PS parameters on produced coatings (porosity, grain size, etc.), various samples with respect to permeability, wettability (heat transfer medium Sodium), capillary height, thermal conductivity, etc., will be tested. Based on the results, a prototype heat pipe will be manufactured and bench scale tests will be carried ou
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Enhancing public awareness on the results of European Health research actions through television media' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The strategic objective of HEALTH-TV is to contribute to the development of public awareness on European Health research in all European countries through television media. This objective will be reached through the exploitation and the customisation of a highly innovative TV media communication model, successfully implemented by the HEALTH-TV partnership over the past 5 years.  The project will: • Fill the existing communication gap between the technical content vehiculed by the Health research and the understanding skills of the general public • Identify the key results of the Health Theme, through the permanent consultation of its relevant constituencies (including the Commission Services) and an in-depth punctual research towards individual Health projects.  • Create a series of 12 high-quality free-of-rights Video News Releases (VNRs) for the general public on the basis of the key results of the research. HEALTH-TV audiovisuals will be conceived in such a way to be easily adaptable to the needs of a wide spectrum of European TV channels, either for news or features usage. The audiovisuals will mostly focus on publicly available Health projects’ results.  • Include HEALTH-TV audiovisual productions into the scientific and news TV broadcasting mainstreams of major national TV channels Europe-wide by targeting broadcast media from the 27 EU Member States.  • Collect actual broadcasts made by European TV stations and include them on a DVD at the end of the project, for future use and exploitation. • Monitor the progress of the project and assess its achievements and success. • Measure the media impact of the project. The project expects to have each of its audiovisual production broadcast by at least 8 major national TV stations throughout Europe and to reach an overal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Relaxation to equilibrium for a disordered particle system' (PARTYMIX).

assistant: **Innovation**

A fundamental result in probability theory states that the distribution of an irreducible, time continuous Markov chain on a finite state space converges to an equilibrium as time tends to infinity.  The study of Markov chain mixing time is a branch of Probability Theory that tries to understand the characteristic of this convergence and answer questions such as: How much time is needed to converge to equilibrium? Is the convergence regular or abrupt?Within this field only little effort have been made to understand how random inhomogeneities can affect the pattern of convergence to equilibrium. The objective of our research project is to develop the mathematical understanding of relaxation to equilibrium of disordered systems.  To do so, we will explore in depth the case of a specific disordered model - the Simple Exclusion Process (SEP) in a random environment -  with the hindsight of developing robust methods which contribute to the understanding of disordered Markov processes.Our project defines a handful of precise scientific questions on which our efforts should be focused. These concern the asymptotic behavior, as the system size go to infinity, of the spectral gap and of the mixing time for disordered Simple Exclusion Process on one dimensional graphs as well as the possible occurrence of the cutoff phenomenon for the process.


**Keywords:** Mixing time, Spectral Gap, Random Environment, Simple exclusion Process, Cutoff.