RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Imagining the Rural in a Globalizing World' to be submitted under Horizon 2020.

assistant: **Abstract**

With globalization primarily considered an urban phenomenon, its impact on rural areas tends to be neglected. Tackling this blind spot is urgent as rural-urban divides persist and rural communities, notably in the 2016 Brexit vote and US election, claim their concerns about globalization’s effects are being ignored. RURALIMAGINATIONS focuses on the crucial role played by cultural imaginations in determining what aspects of contemporary rural life do and do not become visible nationally and globally, which, in turn, affects how the rural can be mobilized politically. Using a distinctive humanities approach, it examines prominent cultural imaginations of the rural in film, television and literature in the UK, US, Netherlands, China and South Africa, asking: 1) to what extent do these imaginations render globalization’s effects on the rural (in)visible? 2) what role do traditional rural genres and the feelings or desires they attach to the rural play in this making (in)visible? 3) how can new aesthetic repertoires highlighting the rural as a site of globalization and addressing rural-urban divides and inequalities be developed? The five subprojects conduct, in their national contexts, a narrative, visual and discursive analysis of post-2000 rural imaginations, guided by an innovative theoretical framework combining three concepts: the chronotope reveals what the imagined rural time-space renders visible and how it relates to urban and global time-space; spectrality gives access to what rural imaginations render invisible and to their haunting by traditional genres; and affect exposes how these imaginations attach feelings and desires to the rural, impacting its evaluation and political mobilization. The project synthesis compares the five contexts and examines how rural im
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'A Novel Nanocontainer drug carrier for targeted treatment of cancer' in the context of a Seventh Framework call.

assistant: **Objectives**

The clinical use and effect of most conventional therapies (e.g. for cancer) are limited, either due to insufficient accumulation of the drug in the target tissue or its severe toxic effects on healthy tissues. Consequently, many treatments are not achieving their full effect and many other highly promising compounds never make it to the market. A promising approach to address this issue of bioavailability is the design and development of nanocarriers. These nanocarriers need to provide stable protection of the compound in the blood stream while they should release the compound at the targeted tissue. Currently, there are no nanocarriers available that effectively address this challenging trade-off.We have constructed nanocontainers (NCs) that show high promise to address this issue. Our NCs are engineered from biocompatible and biodegradable polymers and are unique in their stability and resistance to drug leakage in the circulation, while they exert conformational changes under specific conditions  targeting at the pathological tissue, inducing localised drug release. This technology leverages the fact that tumours (as well as other types of diseased tissue) are known to have specific extracellular environments with lower pH, higher temperature and enhanced glutathione levels compared to healthy tissues. Our NCs integrate four stimuli, namely pH, temperature (T), reducing environments (glutathione) and alternating magnetic fields. With the PoC grant we aim at obtaining in vivo evidence of the functional added value of our proprietary NCs for the delivery of anti-tumour and antibacterial drugs. Furthermore, we aim to strengthen our IP position and develop a business plan thatdescribes theoptimal route-to-market for our technology.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Epidemiology and new generation vaccines for Ehrlichia and anaplasma infections of ruminants' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Heartwater or cowdriosis is a rickettsial disease of wild and domestic ruminants caused by Ehrlichia ruminantium. It occurs in sub-saharan Africa,Madagascar and the surrounding islands where the Amblyomma vectors are distributed. The disease is established in the Caribbean region where it threatens the American mainland. Anaplasma marginale,the agent of livestock anaplasmosis has a wider distribution. It has been identified on all continents where it is transmitted by ticks and biting flies. Both diseases are classified in list B of Office International des Epizooties. Their presence in a country is an obstacle to international trade of animals and losses induced constitute a major constraint to increased productivity of livestock. The objective of the project is to contribute to increased productivity of livestock by controlling the diseases in a context of sustainable production systems and environmental safety. To do so, integrated control is necessary where specific diagnostic and efficient vaccines are essential to reduce the use of acaricides which raise environment and food safety issues. This aim of the project is to deliver improved vaccines, diagnostic tests, risk mapping and economic analysis of vaccine control. Resuts will be obtained by extensive use of modern genomics: annotation, comparative and functional genomics of vector-pathogen interaction aiming to identify genes candidates. After refinement of the protective immune responses analysis, these candidates will be analysed in vitro and on ruminants for their ability to provide protection. New delivery systems and formulations will be applied to these candidates and evaluated for their ability to provide the best protection in a potential field vaccine. Meanwhile, molecular diagnostic (detection and gen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'A program for high throughput molecular diagnostics of the mutation negative syndromic and nonsyndromic craniosynostoses' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Objectives:  To identify the genetic basis of FGFR and TWIST1 mutation negative syndromic and nonsyndromic craniosynostosis  Research Plan: Patient cells from the sutures of FGFR and TWIST1 mutation negative syndromic and nonsyndromic craniosynostosis will be screened for mutations using two genetic approaches.  Firstly genomic DNA from the patient cells will be hybridised to Affymetrix snp microarrays to determine copy number variation.  Secondly the transcriptome of cranial suture cells will be sequenced using the ABI SOLiD technology to identify high quality snps.  If successful this project will identify cryptic cytogenetic or point mutations in critical genes that regulate the morphogenesis of cranial sutures.  Relevance to work program:  This project is intended to be coordinated with an application from a consortium of European molecular genetics diagnostic laboratories for innovative approaches to mutation identification in genetic disorders.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Mechanisms and predictability of decadal fluctuations in atlantic-european climate' in the context of a Fifth Framework call.

assistant: **Objectives**

Problems to be solvedThere is a need of climate-sensitive business and governmental bodies for improved understanding and prediction of fluctuations over decades of Atlantic-European climate. Also, better quantification of natural" climate variability over decades is needed in detection and attribution of anthropogenic climate change.Scientific objectives and approachThe project aims to improve understanding, simulation and prediction of the decadal fluctuations that result from interactions between the ocean and atmosphere. These aims will be achieved through a coordinated programme of numerical experimentation, evaluation against observations, and development of prediction systems. The predictability of decade time scale fluctuations in climate will be quantified and work will be done with targeted user groups in the insurance, utilities and fisheries sectors to assess the potential benefits of decadal forecasts. Output from a series of multi-decadal ensemble integrations from four atmospheric GCM's forced with observed twentieth century Sea Surface Temperature (SST) and Sea Ice Extent (SIE) will be used to assess the potential predictability of decadal fluctuations in the North Atlantic Oscillation (NAO) and other facets of Atlantic-European climate. It will be investigated how the predictability of the atmospheric response to SST anomalies varies with season, atmospheric state and model and how the atmospheric response could feed back to force the ocean. Five ocean GCM's will be used for multidecadal ocean modelling. The models will be forced with observed atmospheric data (NCEP reanalyses), and the skill of the models to simulate major observed dynamic and thermodynamic decadal scale anomalies will be assessed in a common diagnostic framework. Particular emphasis w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'COoperation and NEtworking between Europe and Latin America and the Caribbean to Coordinate Research Opportunities around ICT and Horizon 2020 challenges via Technology PlAtforms' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The CONECTA 2020 project embraces the collaboration between Europe and Latin American/Caribbean Countries around Information and Communication Technologies (ICT) and Horizon 2020. CONECTA 2020 proposes to create new mechanisms of collaboration and networking between Latin American Technology Platforms (LATPs) and ETPs in the form of innovative match-making tools around ICT and Future Internet areas, taking into account issues such as most relevant knowledge and most appropriate user targets depending on specific contexts of their Strategic Research Agendas (e.g., software and services, networked electronic media and ICT for energy) and the roles, social attributes and priorities of each target regional community.<br/>Following the SSA FIRST that successfully created 5 (LATPs) in Argentina, Brazil, Chile, Colombia and Mexico, CONECTA 2020 proposes the creation of 3 new ICT-based Technology Platforms (TPs) in three countries of Latin America: Costa Rica, Peru and Uruguay. CONECTA 2020 will produce organizational documents (governance, structure, etc.) and technical documents (Vision, Strategic Research Agenda), as tools to set up sustainable scientific cooperation between these new LATs and Europe. CONECTA 2020 also proposes the creation of new Working Groups (WGs) within existing LATPs such as the Mexican Technology Platform (MTP): how ICT can support societal challenges such as Secure, clean and efficient energy. CONECTA 2020 will analyze potential areas of cooperation between ETPs and these new Latin American TPs and Working Groups around thematic areas of ICT and applications of ICT sectors, identifying key stakeholders to launch and run TPs in LatAm countries including representatives from industrial (large companies and SMEs) and academic sectors, as well as produci
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Parallel Grid-aware Library for Neural Networks Training'.

assistant: **Concept**

The proposed research is focused on the software library development for parallel neural networks training on computational Grids. The main scientific reason of the proposed research is to develop enhanced parallel neural network training algorithms which provide better parallelization efficiency on heterogeneous computational Grids in the contrast to existing algorithms. The objectives of the proposed research are: 1. to adapt the computational cost model of parallel neural network training algorithms within single pattern, batch pattern and modular approaches to heterogeneous computational Grid resources of host institution; 2. to develop enhanced single pattern and batch pattern parallel neural network training algorithms based on improved communication and barrier functions; 3. to develop a method of automatic matching of parallelization strategy to architecture of appropriate parallel computing system; 4. to develop parallel Grid-aware library for neural networks training capable to use heterogeneous computational resources; 5. to test experimentally parallel Grid-aware library for neural networks training on heterogeneous computational Grid system of host institution within the tasks of one of its active projects; 6. to deploy parallel Grid-aware library for neural networks training on the computational Grid of return host; 7. to test experimentally parallel Grid-aware library on computational systems of both host institution and return host. The cost models of the algorithms will be developed using computational complexity approaches, improved barrier and reducing function will be adapted to neural network parallelization schemes, optimization strategies will be used to find best matching “architecture of parallel system – neural network parallelization scheme”,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'SME Innovation: From research Innovation to commercialisation – the bridge to Horizon 2020 Organizing the European SME Conference under the Irish Presidency of the EU 2013' (EuroSME2013) under Horizon 2020.

assistant: **Objectives**

Concept: to hold the European SME Conference (EURO-SME 2013) conference in Dublin, Ireland during Ireland’s Presidency of the European Union in 2013Objectives:•To contribute substantially to SME-specific policy development and learning•Position enterprise and other research actors for effective commercialisation of research,•Bring Innovation to the market and facilitating SMEs capabilities for growth and jobs•Build on the outcomes of previous conferences in this SME series.The Research for the Benefit of SMEs programme is now recognised as a key element in facilitation of the European SME agenda. The previous conferences have succeeded in bringing together regional, national and European stakeholders including policymakers, enterprises, enterprise development agencies and research communities to address, develop and progress key topics of interest to the community.This two day conference will seek to promote innovation as a means to facilitate growth and jobs for SMEs.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Development of an innovative algae based tertiary wastewater treatment and value recovery system'.

assistant: **Objectives**

Industrial Phycology (IPHYC) has developed a wastewater treatment (WWT) process to meet tightening discharge consents for the concentration of nitrogen (N), phosphorus (P) and other materials in wastewater (WW) effluents. These nutrients & materials are linked to adverse environmental events e.g. eutrophication. WWT operators require a sustainable treatment process to remove / recover these materials to meet legislation.IPHYC's novel patented WWT process uses microalgae (MA) to remove nutrients from WW) effluents. MA reproduce rapidly when sufficient nutrients, light & C02 are supplied. The MA consume nutrients in the WW until depleted cleaning the effluent to the legislated discharge consent concentrations, allowing the operator to meet its statutory commitments & not risk financial penalties. The biomass is retained for reactor seeding or harvested for valorisation e.g. use for anaerobic digestion, animal feed, feedstock for bio-based industries.The process has been validated by I-PHYC in a recent field trial at Wessex Water’s Avonmouth WWT plant & a supporting feasibility study carried out though SME instrument phase 1 support. Through the phase 1 project, IPHYC engaged with the UK water industry to understand the market & end-user needs. From this IPHYC has worked with industry partners to identify the work required to prove its technology & develop its process to commercial readiness. IPHYC is applying for funding to enable it to achieve this by; building a commercial demonstrator of its process for the treatment of municipal wastewaters; optimising its process for the treatment of industrial effluents (e.g. mines); develop methods of recovering value from the algal biomass; further engage with key industry companies, decision makers and potential future customers;
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Inheritance, Demographics, and Economic Development' (IDED) targeting Horizon 2020.

assistant: **Abstract**

Economists study inheritance and demographics in isolation, overlooking the feedback effects between the two. This is surprising given that other social scientists have typically related inheritance schemes to family structures. The general objective of this proposal is to understand the implications of these interconnections for the process of economic development. First, I will create new databases for European countries between the seventeenth and the nineteenth centuries and for Sub-Saharan African countries during the past century until today. These will allow to cover demographic transitions, a crucial stage in the development process in which drastic demographic changes occur, and the period before. These databases will allow establishing facts relating inheritance schemes, family structures and demographic variables. Second, I will propose structural models of inheritance, family structures, marriage and fertility in order to rationalize these facts. These models will assess the importance of the relationship between inheritance and demographics when studying the effect of inheritance on economic outcomes. The databases and structural models will provide answers to specific applied research questions: (i) The Demographic Transition: Was the French Revolution responsible for the demographic transition? What were the relevant channels (partible inheritance and inclusion of women)? How did the abolition  of primogeniture affect the elites’ demographic transition? (ii) The European Marriage Pattern: how did its characteristics; late marriages and high life-long celibacy, vary across inheritance systems? Which one of these was most beneficial for gender empowerment? (iii) Sub-Saharan Africa’s demographic transitions: Can the harmonization of inheritance practices rea
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Ex vivo gene delivery for stem cells of clinical interests using synthetic processes of cellular and nuclear import and targeted chromosomal integration' (SYNTHEGENEDELIVERY) targeting Sixth Framework.

assistant: **Abstract**

Our aim is to develop SyntheGeneTransfer (SGT), a new ex-vivo gene delivery protocol to provide stable long-term expression of integrated transgenes. Our clinical objective is to provide gene therapy solutions for some genetic diseases of the neuromuscul ar and skeletal systems as well as circulating-polypeptide deficiencies that together afflict over 35,000,000 patients in Europe. We have therefore selected mesenchymal and muscle stem cells as model systems in which to develop the SGT protocol.The SGT p rotocol is designed to overcome three key barriers: transgene internalization in stem cells, transport within the nucleus and integration at a predefined safe" genomic locus that will permit transgene expression. To achieve these goals and fully develop the technology, this application draws together a multi-disciplinary European team from four public laboratories and two SMEs. To overcome serious problems with current transfection methods, the teams will develop protocols for internalization and nucle ar membrane transport based on Lipoplex, block copolymers and Bioplex. To overcome serious problems with current integration systems, a new targeted transposition system will be developed using a Mos1 transposon.Our main technical objective is to enginee r SGT to provide a method for the integration of large transgenes that will be highly efficient and maintain a stringent safety by preventing the oncogenic transformation of the target cells. Optimization of the cellular internalization and nuclear impor t steps will allow the cells to be treated with a minimal amount of the transgene. This will minimize the probability of illegitimate integration events at unexpected genomic loci. To optimize the integration step of the process, the Mos1 transposon will be engineered to