RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Information Frictions, Financing and Growth:  The Impact of Firm Certification'.

assistant: **Innovation**

This project will provide new knowledge on the mechanisms through which finance, and the relaxation of informational frictions for firms can promote economic growth. A big challenge in the field of corporate finance is to establish causality, and cleanly identify the impact of frictions on corporate outcomes. I aim to transform the frontier of knowledge in my field by using state of the art methodology in finance and economics that allows inferring causality.  I will exploit a public policy program of certification (rating) of firms that was introduced in Portugal in 2008 by a governmental agency as a laboratory to estimate the impact of informational and financial frictions on corporate performance. This program has unique features that permit a Multidimensional Regression Discontinuity Design to estimate the causal economic impact of firm certification, and access of firms to financing. I will investigate both in detail, and in a comprehensive approach the channels through which the links between informational frictions, access to financing and corporate growth operate. The richness of the data on Portuguese firms makes it possible to understand the role of productivity, investment, innovation, human capital (employment), and trade. Last, I will study externalities generated by firm certification on a broader network, which includes other firms in their supply chain but also financial institutions.  This research has obvious and relevant policy implications for governments because it will measure the economic effects of relaxing financing constraints, and it will provide a better understanding of the channels through which financing and informational frictions operate to impact firm performance.


**Keywords:** information,  certification,  growth,  financing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'New Approaches to Uncover Dark Matter in the post-WIMP Era' in the context of a Horizon 2020 call.

assistant: **Objectives**

Uncovering the particle nature of dark matter (DM) is one of the primary goals of fundamental physics and cosmology today. DM accounts for 85% of the matter in the Universe, but only its gravitational effects on the motion of celestial objects have been observed. DM research is arguably in a critical state: the long-prevailing WIMP (weakly interacting massive particle) paradigm has not been confirmed experimentally up to now, putting the focus on the electroweak scale under serious pressure. I played a leading role in both identifying and bringing to fall some of the most promising WIMP signal candidates, thanks to new data analysis and modeling techniques that I continuously develop and employ with my group. Furthermore, I am an initiator and lead developer of a powerful new analysis framework for combining a vast range of astrophysical, cosmological, collider and laboratory data, which now forms the core of the most accurate global studies of DM theories.My goal is to discover particle DM in the post-WIMP era, both by introducing new approaches and by adapting methods that I successfully developed for WIMP searches. I will conclusively probe astrophysical hints for sterile neutrino and axion DM, which are the most promising DM candidates next to the WIMP. However, given the hundreds of valid DM models on the market, one should be wary of repeating the fixation on specific energy scales yet again. I will develop an urgently needed 'principled lampposts' approach to identify gaps in searches for a large number of DM models across the scales. I will cover substantial unexplored territory in the axion and sterile neutrino DM parameter space with upcoming radio and X-ray data, study indirect detection signals over a large range of frequencies, and constrain the substructur
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Innovative Methods of Separated Flow Control in Aeronautics' to be submitted under Seventh Framework.

assistant: **Abstract**

The IMESCON network is a high quality training network to produce well qualified researchers in the area of active flow control and new helicopter technology. This training programme of best quality early stage and experienced researchers from industry and academia will combine expertise from fluid dynamics, composite material, Micro Electro Mechanical Systems (MEMS), experimental techniques and numerical modeling of coupled multiple simultaneous physical phenomena.Proposed research project of mutual interest to partners will address key questions in the complex multi physics phenomena research related to active flow control with the application of the novel piezoelectric materials. In energy consuming applications like aircraft operation active flow control is effective method of substantial fuel consumption and thus CO2 emission reduction. Flow control methods influence the flow unsteadiness, thus impact the increased durability of the manufactured elements and noise reduction.Combination of the two cutting-edge technologies, the MEMS and the active flow control will provide an excellent training and career development path for researchers who wish to work on analysis of the combined effects of multiple physical phenomena in environment-friendly modern technologies. Proposed project will foster existing long term collaboration between partners and create new collaborations through recruited researchers. The project outcomes will both serve the designers of the next-generation aircrafts and at the same time strengthen the human potential in R&D in Europe.IMESCON is Marie Curie ITN training programme involving 2 large European helicopter designers and manufacturers, 2 SMEs specialised in MEMS, 3 world class academic research groups and prime engineering innovation partn
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'ADVANCED ANTIGEN-SPECIFIC DENDRITIC CELL-BASED THERAPY TO RE-ESTABLISH TOLERANCE IN IMMUNE-MEDIATED DISEASES' in the context of a Horizon Europe call.

assistant: **Objectives**

Autoimmune diseases are currently treated with immunosuppressive and supportive therapies, which dampen inflammation, but do not stop the cause of the disease and are required life-long. Thus, there is an unmet need for safe and effective therapies for these diseases, which are well-tolerated and targeting the cause of disease. Tolerogenic dendritic (DC) cell-based therapies, offer the possibility of restoring immune regulation leading to long-lasting effects. Vitamin (Vit)D3-modified tolerogenic DC have been recently applied to Multiple Sclerosis (MS) patients in Phase I trials, demonstrating safety, tolerability, feasibility, and preliminary evidence of an effect. Molecular characterization of VitD3DC from MS patients suggests that they own less tolerogenic properties than those from healthy individuals. Thus, correcting these deficiencies through gene transfer could improve their effectiveness. The aim of IMMUTOL is the fast-track development and validation of an advanced therapeutic medicinal product (ATMP) based on VitD3-modified tolerogenic DC for immunotherapy approaches. Through a multidisciplinary approach, IMMUTOL will leverage the power of tolerogenic VitD3DC-based immunotherapy to develop a more potent and durable treatment for MS and, in turn other autoimmune inflammatory diseases with an unmet medical need. In parallel, it will bring information about tolerance mechanisms and patient-specific requirements for manufacturing effective tolDC products. Results will lead to design of a clinical protocol according to the regulatory requirements for the first-in-man application of engineered tolerogenic VitD3DC in MS patients.


**Keywords:** Tolerogenic dendritic cells, tolerance, VitD3, cell therapy, autoimmune diseases, multiple sclerosis, auto inflammation, a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Archéomatériaux composites de l' architecture en mediterranée : verre-terre cuite altération et recréation'.

assistant: **Innovation**

- Le programme ARCHI-MED concerned les matériaux composites verre-terre cuite utilisés pour la décoration architecturale dans les pays méditerranéens. Ils posent aux urbanistes, aux architectes et aux entreprises chargés de réhabiliter certains édifices anciens (maisons privées, palais, mausolées, mosquées...) divers types de problèmes de préservation liés à leur présence sur des murs ou sur des sols : . Comprendre, afin de les contrôler, les processus d' altération de ces matériaux et de leurs supports. . Disposer de données précises sur les caractéristiques physiques (texture, constituants) de ces matériaux, afin de les reproduire.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'MembrAnEs for STationary application with RObust mechanical properties' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Low equivalent weight ionomers are required to reach the membrane conductivity and MEA performance targets for stationary operation and enable stationary PEMFC systems to achieve superior overall system yield to competitive technologies. Perfluorosulfonic acid ionomers (PFSA) demonstrate excellent properties in terms of chemical resistance in a fuel cell environment. In stationary applications, where the situation of deep MEA dehydration and frequent open circuit voltage events can be reasonably avoided, (this is not true in automotive applications) the most relevant failure mode in extended life time operation is associated with membrane mechanical failure. The use of a pre-formed inert support for mechanical stabilisation within the membrane has the drawback of reducing membrane specific conductivity, and this frequently imposes a reduction in membrane thickness to very low values. The objective of this proposal is to improve the mechanical properties of low equivalent weight state of the art perfluorosulfonic acid membranes using chemical, thermal, and processing and filler reinforcement methodologies by maintaining high proton conductivity. The baseline product for further development is the short side chain perfluoroionomer that already shows the best combination between ionic conductivity and mechanical stability. Stabilised membranes will be comprehensively characterised for their ex situ properties and screened and selected membranes will be integrated into MEAs and validation by  evaluating single cell performance and durability under conditions relevant for stationary operation and comparison with those of reference membrane materials and MEAs, including the development and application of accelerated stress testing. In the final phase of the project the most p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Side Channel Analysis Resistant Design Flow' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

The threat of side-channel attacks is of crucial importance when designing systems with cryptographic hardware or software. Especially smart cards and related micro-chip systems have shown considerable vulnerabilities in this respect. Side-channel attacks analyse and exploit the information produced by some system by, for example, measuring its power consumption or the electro-magnetic emanation of this system. From these traces the attacker can potentially make conclusions about the secret data involved in a computation inside the system.Meanwhile, simple power analysis (SPA), differential power analysis (DPA), and their related attacks, simple and differential electro-magnetic emanation analysis (SEMA, DEMA) became known to a broader public, and thus pose the biggest threat. In the following, we will refer to these side-channel analysis methods and related attacks by using the acronym SCA. In SCARD, we propose to enhance the typical micro-chip design flow - from high level system description over register transfer layer description down to gate level net lists, and finally placement and routing of the micro chip - in order to provide a means for designing side-channel resistant circuits and systems.Moreover, we intend to study the whole phenomenon of SCA in a consistent manner, and will also provide appropriate analysis tools and design tools for the designer of secure systems. We consider these additional ingredients of the traditional design flow of micro chips as necessary in order to enable the design of the next generation of secure and dependable devices.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'ISOTOPIC LABELING FOR DRUG INNOVATION' (ISOTOPICS).

assistant: **Innovation**

Excessive attrition rates during clinical trials dramatically impact on Drug Discovery and Development (DDD). Absorption, Distribution, Metabolism and Excretion studies carried out on larger series of drug candidates at an earlier stage of the DDD timeline and evaluation of drug efficacy through better assessment of pharmacokinetic/pharmacodynamic relationships, target engagement and receptor occupancy are critically important approaches for de-risking drug innovation since they facilitate early identification of the candidates that display the best in vivo profile. When successfully implemented, this strategy can accelerate the discovery of new therapeutic solutions to existing and emerging diseases, and enhance European pharmaceutical innovation. For implementation, large sets of isotopically-labeled molecules are required and consequently, a huge revival of labeling techniques is urgently needed. Another crucial issue is the scarcity of expert radiochemists in Europe and the lack of first class training programs in this inter-disciplinary field merging chemistry, radiochemistry and medicinal chemistry. The aims of ISOTOPICS are: i) to train the next generation of European chemists with expertise in isotopic labeling and advanced medicinal chemistry through a first-class taught and research training program combined with a highly interactive secondments plan; ii) to develop innovative and general isotopic labeling chemistry and radiochemistry to streamline the synthesis of labeled small-molecule drugs and biologics; iii) to work closely with the European pharmaceutical industry to apply the new labeling methods to drugs currently in development in order to provide solutions to the most pressing problems in drug innovation. This highly interdisciplinary project is expe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Development of a new plant variety for the Asian market'.

assistant: **Innovation**

Palms are some of the most successfully traded plants, with numerous species sold for indoor, outdoors and as crops. The kentia palm (Howea forsteriana), is one of the most widely exported houseplants in the world and is worth over seven million euros per year in the Dutch horticultural industry alone. Wild kentias are only found on a 12km2 island in the middle of the Tasman Sea, Lord Howe Island (LHI). LHI is a unique ecosystem. It is the focus of the applicant's ERC Advanced Grant, who is using the kentia palms as a model to tackle 'Darwin's mystery of mysteries'. During our expeditions on LHI, we have also discovered a new mutant variety of the kentia palm: instead of having the typical dark green colouration, it has a bright red stem.  Red-stemmed varieties of palms are known, but have had very limited commercialisation due to climatic restrictions: these palms are tropical species, requiring high humidity and temperature. In contrasts, kentias are very hardy and grow well under low light and cool temperatures, hence their immense success as decorative items across innumerable indoor public venues and households. In addition, red is an auspicious colour in Asia – and we know our new red kentia palm has tremendous horticulture potential. Building on our genetic research and experiments with these kentia palms, we propose to disentangle the biological underpinning of the red stem. In parallel, we will conduct a market research. Examining our IPR position and strategy, we will take the necessary steps to protect our variety, including its registration as Ornamental  Crop  to the Community  Plant Variety  Office.  Finally,  we will strengthen  our links  with  various industries and private stakeholders to develop a business plan for commercialisation of red kentias
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Advanced Load Sensing technology for Aerospace Application' (TecALSens) targeting Horizon 2020.

assistant: **Abstract**

The objective of the TecALSens project is the provision of an advanced and validated load sensor for integration in the Smart Integrated Wind Demonstrator and validation in an industrially relevant environment. The project covers the whole process chain taking into consideration specific requirements: from designing of all sensor components through manufacturing of load cell, electronics and sensor body up to validation and verification of its properties and operational behavior. Electronics will be designed and manufactured considering DO-254 specifications; The complete systems will be tested according to DO-160 requirements. In TecALSens a two-step approach will be pursued. After manufacturing, the load sensor will be tested for TRL 4 and TRL 5 compliance. The design phase will support the experimental validation by taking into consideration the environmental conditions. On the basis of these results a critical review and improvement of all steps will be performed. The improved sensor will be tested again following the same procedures. The project will provide a robust and reliable solution based on innovative sensor principle for further application in primary, secondary flight controls and landing gear systems. With this solution  their functional safety can be enhanced. An industrialization path will be defined and verified at each step for further production.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Targeting of host proteins by unrelated pathogen effectors and their surveillance by allelic immune receptors'.

assistant: **Objectives**

Pathogens secrete effectors into host cells to promote virulence and often establish disease by interception of basal defence components. One widespread mechanism of disease resistance in plants requires nucleotide-binding oligomerization (NOD)-like receptor (NLR) genes. Recognition of an effector by a cognate NLR prevents pathogen proliferation. A co-evolutionary arms race between the host barley and the pathogenic powdery mildew fungus Blumeria graminis forma specialis hordei(Bgh) has driven the functional diversification of allelic NLR variants encoded at the MLA disease resistance locus (for Mildew locus A). Recent work revealed that Bgh effectors detected by allelic MLA receptor variants are unexpectedly sequence-unrelated and evolved independently from different ancestors. Additionally, the MLA orthologs in wheat and rye, Sr33 and Sr50, confer isolate-specific resistance to the stem rust pathogen Puccinia graminis forma specialis tritici (Pgt). This is remarkable because rust and mildew fungi belong to different phyla and cannot encode sequence-related effectors. MLA variants can therefore not have diversified to directly bind sequence-related effectors and thus monitor effector-mediated modifications of host targets conserved between different cereals. To reintegrate into the European scientific community, I wish to perform the “TOPPER” project at the Max-Planck Institute for Plant Breeding Research, Cologne, Germany.The “TOPPER” project will clarify whether the sequence-unrelated Bgh effectors target the same host protein or converge on a common signalling pathway/complex consisting of related or unrelated host proteins. I hypothesize that the host protein(s), manipulated by Bgh effectors, is/are also targeted by effectors of other plant-associated microorganism