RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Assessing the feasibility of MT-011, a first-in-class drug to treat glaucoma and other neurodegenerative diseases via a breakthrough mechanism-of-action' (SA-VOIR) targeting Horizon 2020.

assistant: **Abstract**

Glaucoma is the world's leading cause of irreverisble blindness, affecting 20 million people in Europe and the US. Known as the Alzheimer’s of the eye, glaucoma is a neurodegenerative disorder that causes deterioration in peripheral vision. Affected patients report ‘seeing through a black tunnel’. Treatments to halt vision loss are available however, they are only applicable for the ‘high tension glaucoma’ subtype. For those diagnosed with ‘normal tension', which comprises over 30% of glaucoma patients, no treatments are available, and vision loss is imminent. New drugs that inhibit VASH, a newly elucidated enzyme that is hyperactivated in many neurogenerative diseases, have potential to address this need. We at MT-act are a biotechnological start-up who have identified a family of VASH-inhibiting small molecule drugs. Using an in-house proprietary biochemical assay followed by lead optimization, we have identified MT-011, which inhibits VASH with nanomolar affinity, as our lead candidate. Aside from glaucoma, VASH dysregulation is also implicated in other prominent neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Our assets therefore have an inherently broad applicability. We aim to develop MT-011 up to the stage of Phase 1 clinical trials, upon which we aim to commercialize the drug via a licensing deal with a pharmaceutical partner. We will then receive upfront and milestone payments with a estimated total deal size of €40M. We are currently in discussion with world-leading pharmaceutical companies Pfizer and Santen Pharmaceuticals, who have already indicated interest in our drugs.In SA-VOIR, we aim to strengthen the business case for MT-011 and to outline a detailed technical plan for its continued development. These documents will not only guide us i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Deformed geometry and phenomenology' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Modern physical approach to non(anti)commutative geometry lies on the concept of effective field theory". In the main framework of String Theory, quantum field theories defined on such deformed structures appear in the low energy limits of particular configurations of D-branes, preserving different amount of supersymmetry, according with the deformation involved.Therefore besides the mathematical aspects of these space-time deformations, a phenomenological perspective is needed and powerful algebraic and geometric methods can open new interpretation of physics of Standard Model and beyond that. The proposal is to pursue the study of non(anti)commutative geometry from this point of view, by focusing on the compelling problem of supersymmetry breaking.Since low energy supersymmetry is the first natural step for physics beyond the Standard Model at TeV scale, one of the central questions is to understand the mechanism of its breaking. In particular, most phenomenological issues of these models, like cosmological constant, R-parity violation, leptonic and barionic number conservation, are determined by soft terms, those which avoid new harmful divergences.Supersymmetric models defined on a manifold with deformed geometry have been recently shown to produce such a soft breaking. A deeper study of the different possibilities given by deforming the structure of the space-time is allowed in the natural setup of superspace, where suitable techniques allow for a simpler analysis of both classical and quantum properties."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Predicting recovery in acidified freshwaters by the year 2010 and beyond.' in the context of a Fifth Framework call.

assistant: **Objectives**

Problems to be solvedRECOVER: 2010 is designed to assess the impact of current and future anthropogenic pressures on sensitive European freshwater ecosystems. RECOVER: 2010 will evaluate the present extent of recovery of acidified freshwaters, and identify and quantify the dominant driving processes governing the timing and magnitude of recovery. This Pan-European assessment will use enhanced predictive models to evaluate the degree of compliance with respect to restoration of acidified waters by the year 2010 as specified under the Water Framework Directive. Similarly, agreed and proposed UN-ECE protocols on emissions control will be critically assessed and economic costs and environmental benefits evaluated with respect to the recovery of freshwaters.Scientific objectives and approachEmpirical data from different acidified European ecotypes will be evaluated to provide measures of time lags in response to changes in emissions of acidifying compounds, and indeed to separate out the different contributing processes. Regional controls on sulphur dynamics, and the role of nitrogen in the recovery process will be determined. Current conceptualisation of the recovery process has not considered potential interaction with natural variations such as climate-induced impacts, and RECOVER: 2010 aims to assess the magnitude and spatial extent of these confounding factors. Current dynamic modelling approaches will then be enhanced through improved process representation, and through the linking of hydro chemical changes to biological impacts and time lags in ecosystem recovery. An evaluation of Pan-European existing and proposed emission controls will then be undertaken to determine spatial and temporal patterns of response. Feedback from the modelling evaluation will be central to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Aoi' (AOI).

assistant: **Concept**

The field of Atom Optics and Interferometry has undergone a tremendous growth during the last years. The possibility to guide and store atoms in laser and/or magnetic structure, combined with cooling methods based either on atom-light interaction or evaporation of particles, has led to spectacular developments both in our understanding of the properties of dilute matter at ultra-low temperatures, and in the achievement of new optical elements and sensors using atoms.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Bacterial stress management relevant to infectious disease and biopharmaceuticals' in the context of a Sixth Framework call.

assistant: **Objectives**

While bacteria remain one of the main threats to human health and well-being, particularly in the light of increasing resistance to antimicrobials, they also have the capacity to provide products (e.g. antibiotics, vaccines and biotherapeutics) that have a positive influence on human health. Thus, bacteria are both targets for, and producers of, biopharmaceuticals. BACELL HEALTH is a research and technological development project that aims to address both the negative and positive characteristics of bacterial behaviour by undertaking an integrated and in-depth study of the response of Gram-positive bacteria to stresses encountered by pathogens during infection and by industrial strains during bioprocesses. The ability of bacteria to detect, respond and resist environmental insult is a key element in their survival and productivity. The physical and chemical insults to which bacteria may be subject, range from generic stresses, encountered by most unicellular organisms in the environment, to specific stresses encountered by pathogens during infection or by engineering strains during ndustrial bioprocesses. The main objective of this proposal is to develop a profound understanding of the integrative cell management and associated stress resistance processes that are essential for sustaining bacteria as effective pathogens or as efficient producers of pharmaceutically-active proteins.Studies on relevant generic stress responses will be carried out on the genetically highly amenable model bacterium Bacillus subtilis, but will be extended to pathogens in the same (e.g. B. anthracis, B.cereus) and related genera (e.g.Listeria monocytogenes, Staphylococcus aureus, Streptococcus pneumoniae). The proposal aims to model the regulatory networks that comprise the Cell Stress Manage
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Collective electronic states in nanostructures' (COLLECT).

assistant: **Concept**

Advances in fundamental nanoscience have the potential to create novel technologies in information science and new research directions in modern solid-state physics. This network program is aimed at implementing advanced experimental and theoretical approaches for the production, understanding, and manipulation of collective phases of electrons in low-dimensional systems. The main research topics that will be addressed during the network programme are: coupled multilayer electron systems, frictional drag in coupled bilayers, multicomponent quantum Hall magnets and their soft collective excitations, spin phases and Kondo physics in single and coupled quantum dots, non-Fermi liquids and electron transport in semiconductor quantum wires, molecular wires and carbon nanotubes, Wigner crystallization in ultralow density quantum Hall systems and soft magneto-roton excitations, composite-fermion states, charge-density wave states at high Landau level occupancy, coherent states in hybrid semiconductor/superconductor heterostructures, carrier-mediated ferromagnetic phases in semiconductor materials. The research programme will strongly benefit from the expertise and competence of some of the leading European experimental and theoretical groups in this field and will exploit a broad range of complementary techniques for the investigation of such phenomena together with advanced nanofabrication and growth protocols for the realization of suitable state-of -the-art nanostructures. Two world-leader US-based research teams will take part in the network too and will contribute by expanding the training opportunities offered by this network with their competence in spectroscopy and theoretical studies of quantum Hall liquids. Their involvement will exploit a new funding opportunity that
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Development Of Microfluidic Based Low Cost Industrial Cryo-Ready Devices For Preservation Of Living Cells' (MCRD) targeting Horizon 2020.

assistant: **Abstract**

Innovation in development of cell therapy products are growing rapidly. As per the report of WHO, in the year 2015, total 38 such innovation has been taken place in EU region and other developed countries. Such accelerated growth of the technology leads WHO to configure regulatory issues for the clinical storage and applications of these developed products. Thus, on the basis of current requirements, there is a immediate need to develop systemic research and infrastructure for storage of the developed biological products for longer duration of time. Cryopreservation, lyophilization, and desiccation are the major techniques been used for the preservation of biological products, namely different types of cells. But all above mentioned process are highly toxic while considering cellular viability. At the same time, this processes are bulky and involves substantial cost affair. In current project proposal, ER in collaboration with Eden Microfluidics have proposed development of a microfluidic based cryo-ready device for plug-and-play type cell / biological sample storage, testing, and laboratory usage. The proposed technique is highly inter-disciplinary, and with the experience of ER and his mentors from Eden Microfluidics, they are confident for the development of the product. The development of the product will yield new insight of physical biology in the field of magneto-hydrodynamics, biological thermodynamics, and bio-microfluidics. The proposed project is not only limited to the development of product, but it will extend the work for marketing and production of the product, and dissemination of the acquired field of science to the national and international universities as text contents (in form of book chapters), laboratory tutorials through the collaborations of ER.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'On-vehicle laser microsystem for obstacle detection' in the context of a Fourth Framework call.

assistant: **Objectives**

To demonstrate the feasibility of a miniaturized and integrated obstacle detection system based on laser technology, to be used for automotive applications, particularly Intelligent Cruise Control and Anticollision.To develop and make available the technology of small,eye-safe, solid-state microchip lasers with fast risetime and high peak power.To develop solutions for efficient laser beam scanning, which can withstand vibrations and guarantee long lifetime, integrating microoptics and micromechanics.To support the industrial evaluation of technologies for driver support functions, by a comparative assessment of the developed solution, and a review of application trends.A functional prototype of a compact laser-based system for obstacle detection on-vehicles is to be developed. New microsystem technologies are to be used to address the requirements of reliability, detection performance in adverse visibility, eye safety, and cost effectiveness. The key technologies are an eye-safe microchip laser at 1,5 um wavelength, and a beam-scanning system based on micromachined lenses and flexure structures for actuation. Original signal processing circuits will be developed, where time-of-flight and correlation techniques are integrated, aiming to improve the operation in bad atmospheric conditions. A technical evaluation, including real-field tests, and an overall assessment of the solution will be performed. The system for obstacle detection will be the core component for driver support functions, with an high impact on safety, traffic efficiency and driving comfort. New application areas are also anticipated such as instrumentation, industrial automation and security systems.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Rigidity of groups and higher index theory'.

assistant: **Concept**

The Atiyah-Singer index theorem was one of the most spectacular achievements of mathematics in the XXth century, connecting the analytic and topological properties of manifolds. The Baum-Connes conjecture is a hugely successful approach to generalizing the index theorem to a much broader setting. It has remarkable applications in topology and analysis. For instance, it implies the Novikov conjecture on the homotopy invariance of higher signatures of a closed manifold and the Kaplansky-Kadison conjecture on the existence of non-trivial idempotents in the reduced group C*-algebra of a torsion-free group. At present, the Baum-Connes conjecture is known to hold for a large class of groups, including groups admitting metrically proper isometric actions on Hilbert spaces and Gromov hyperbolic groups. The Baum-Connes conjecture with certain coefficients is known to fail for a class of groups, whose Cayley graphs contain coarsely embedded expander graphs. Nevertheless, the conjecture in full generality remains open and there is a growing need for new examples of groups and group actions, that would be counterexamples to the Baum-Connes conjecture. The main objective of this project is to exhibit such examples. Our approach relies on strengthening Kazhdan’s property (T), a prominent cohomological rigidity property, from its original setting of Hilbert spaces to much larger classes of Banach spaces. Such properties are an emerging direction in the study of cohomological rigidity and are not yet well-understood. They lie at the intersection of geometric group theory, non-commutative geometry and index theory. In their study we will implement novel approaches, combining geometric and analytic techniques with variety of new cohomological constructions.


**Keywords:** Kazhdan's prop
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Leveraging data and AI to empower citizens to make healthier and more sustainable food choices'.

assistant: **Objectives**

WiseFood aims at developing smart digital applications that will empower citizens to make healthier and more sustainable food choices. It will leverage state-of-the-art Artificial Intelligence (AI) techniques and tools, combining the factual knowledge representation capacity of Knowledge Graphs with the natural language understanding, generation, and reasoning abilities of Large Language Models. These will allow us to build novel tools that democratize access to reliable food-related information and go beyond the current levels of personalization and contextualization offered by existing food recommenders. The developed applications will be user-friendly and integrate seamlessly into daily life, not requiring specialized IT skills or devices. Our goal is to bridge the divide between knowledge, intention, and action with end-to-end intelligent solutions. A human-in-the-loop approach with food domain experts, including nutritionists, will be applied to ensure alignment with national policies and guidelines. Living Labs implementing a multi-actor approach are foreseen to co-create the envisioned solutions. These will take place in three different countries, Ireland, Hungary, and Slovenia, with the latter being an already established and operational short food supply chain Living Lab. The outcomes of WiseFood will enhance the overall food ecosystem, by promoting healthier dietary habits, reducing the ecological footprint of food consumption, and fostering a culture of well-informed and eco-conscious citizens.


**Keywords:** food recommender systems, digital recipes, information extraction, living labs
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Indian and European Local Energy CommuniTies for Renewable Integration and the Energy Transition.'.

assistant: **Innovation**

An increasing role is foreseen in Europe for local energy communities (LECs) to speed up the grid integration of RES. To-day, the enabling role of DSOs in support of LECs is hampered by a lack of flexibility when planning cost-efficient LEC connections to their network at MV level, and by a lack of digitalization of the LV networks to make LEC’s smart prosumers benefit economically when serving the DSO flexibility needs. Four European DSOs (E.ON, ENEDIS, E.DIS, Güssing Stadtwerke) and an Indian DSO (TATA) have joined with IT-based, innovative product and solution providers, and technology and research centers, to demonstrate the combined roles of innovative functionalities serving the MV and LV networks, when implemented in 5 different regulatory regimes (Austria, France, Hungary, Germany, India- state of Delhi-).For MV networks, a mobile storage concept at substation level is demonstrated in Hungary, Germany and Austria. It enables DSOs to reduce investment uncertainties, avoid hindering future renewables connection and foster the local use of flexibility with participating non-regulated market solutions (Demand Side Response-DR-).  For LV networks, 3 functional use cases served by ATOS and Schneider are tested simultaneously in Austria and India with prosumer support: i) Forecasting/scheduling of Distributed Energy Resources for the optimized energy management of Local Energy Systems, ii) Customized, human-centric prosumer participation in explicit DR programs using context-aware flexibility profiles, iii) Grid-forming/islanding capabilities in Local Energy Communities to optimize their energy system resilience. The joint work of DSOS aims at accelerating scaling up and replication tested by HEDNO (Greece) and E.ON (Sweden). Dissemination towards players of the energy