RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Engineering perennial barley' (PERLIFE).

assistant: **Concept**

Today, annual crops account for more than 85% of the worldwide calorie consumption. Annual crops are sown and harvested within one growing season and therefore require annual tillage, and application of herbicides and fertilizers that cause land and water degradation. In contrast, perennial crops grow over many seasons, require low agricultural input and thereby hold great potential for sustainable production systems and climate change adaptation. However, current efforts to breed perennial cereals are hindered by hybridization barriers between annual crops and wild perennial relatives and the trade-off between longevity and seed yield.PERLIFE pioneers the knowledge-based engineering of perennial traits in annual crops using the important annual crop barley as study system. This project will thus open entirely novel avenues for breeding perennial crops. PERLIFE capitalizes on 1) recent technical advances in high-throughput genome sequencing for the identification of genetic variants and 2) the novel genome-editing technology Crispr/CAS9 for the targeted transfer of genes between species. PERLIFE will isolate genetic variants promoting perennial growth using comparative genomics in annual and perennial wild relatives of barley. In interspecific crosses, we will dissect the interrelationship of longevity and seed yield and identify linked coding and regulatory variation. Based on this information, we will design and implement strategies for the targeted modification of longevity in barley using transgenic approaches and genome editing. The engineered genotypes will be trialled in environmental simulation chambers for longevity, stable seed yield and stress resistance to select the most successful engineering strategy. This ground-breaking work will provide a highly effici
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Virtual enterprise using groupware tools and distributed architecture'.

assistant: **Concept**

The VEGA project aims to establish an information infrastructure which will support the technical and business operations of Virtual Enterprises. Groupware tools and distributed architectures will be developed in compliance with product data technology standardisation activities in line with the current trends adopted by international industrial groupware specifications coming for example from the Object Management Group.The VEGA project will develop a methodology for the distribution of systems and achieve the integration expected by end users by following two complementary routes. The approaches and developments resulting from a number of ESPRIT projects will be extended and the strategy for application integration by the distribution of a concurrent access to STEP databases will be explored to its ultimate limits. The second route will involve designing a COrba Access to STep models (COAST) infrastructure to support, as a natural mechanism, the distribution of product data by means of an updated object broker technology.VEGA will focus on a business case where these technologies could bring more benefits than in the manufacturing sectors. The Large Scale Engineering industry (20% of the GNP of EC nations) is a fragmented industry where the business relationships last only for the duration of the projects. This is a typical case of Virtual Enterprise with an increased world-wide competition and special threats coming from low wages areas. VEGA will establish a generic backbone for a new communication era based on the distribution of product model data.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'European Science Festival: Itinerant Exhibitions'.

assistant: **Concept**

At the light of the big success of the first three editions, the Genova Science Festival has become an annual event. In the second edition, the network ESCIENTIAL, granted by the EU Commission, significantly enhanced the European dimension of the Festival, with the contribution of qualified EU organizations. The new project ESCIENTIAL I.E. aims at further improve the European spin-off of this event, contributing to the integration of science in society at a European level", with the following tasks andfeatures:- Expert and "apprentice" science "guides" coming from EU Museums. Science Centres and from the Science Festivals members of EUSCEA network will participate to a series of social-cultural events aimed at the launching of the European Academy for Science Explainers (EASE). The main initiative inside EASE will be the second edition of the International Workshop on Science Communication. During the Workshop EASE participants will contribute with their knowledge at the training phase of the guides of the Genova Science Festival (over 500), sharing experiences and discussing on how to communicate science and promote people's interest in science. - The consortium will bring in Genova, during the Science. Festival, exhibits and laboratories to enrich the programme of the Festival. It is fundamental to underline that ESCIENTIAL I.E. project involves now new EU member States, with the objective of sharing experiences and facing the intercultural differences and the different role of educational systems.- The project shares the same objective as ESCIENTIAL, but with a new strategy aimed at turning the events presented at the Festival into itinerant exhibitions. Thus the Genova Science Festival can be seen as a showcase to present, illustrate and test events, the most succes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Dendritic integration by nanoscale neuroanatomy' (DNA) under Horizon 2020.

assistant: **Objectives**

Understanding how single neurons integrate and process incoming synaptic signals to generate a physiologically meaningful output remains a fundamental question in neuroscience. While much is known about how the integration of synaptic inputs is governed by overall dendritic geometry and ionic conductances along the dendritic membrane, the role of the micro-anatomical structure is yet to be deciphered. Although theoretical work suggests that structural details of dendritic spines might play a major role for synaptic function and dendritic integration, it has been experimentally difficult to address this long-standing hypothesis. While electron microscopy allows the visualisation of spine ultrastructure, it is incompatible with studying spine function in live brain tissue. I propose to combine state-of-the-art STED microscopy with holographic photolysis to examine the influence of spine morphology on dendritic integration of CA1 pyramidal neurons. STED microscopy will reveal spine morphology, while holographic photolysis will be used to stimulate multiple synapses at the same time with high spatio-temporal precision. This novel approach, relying also on electrophysiology and compartmental modelling, will make it possible to study the influence of nanoscale morphology on dendritic integration of multiple synaptic inputs. The project builds on my expertise in cell biology and neuroanatomy, and will give me the opportunity to master advanced opto-physiological methods in a host environment that is well known for bio-imaging and neuroscience. Given my strong background in neurodevelopmental disorders, the project will push the knowledge frontier on neuronal processing and will provide a framework for research into basic mechanisms of neurological disorders.


**Keywords:** De
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Directed Evolution in Femtolitre Microreactors - Exploring 'Promiscuity Space'' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The ‘vastness of sequence space’, i.e. the extremely large number of possible permutations in even the smallest catalytic proteins, requires evolutionary shortcuts. In this project the candidate will interconvert members of a promiscuous catalytic superfamily into one anotehr and differentiate a multi-specific enzyme into mono-specific mutants.  Ultimately it is hoped that directed evolution experiments will have implications for the definition of ‘phylogenetic relationships’ for catalysis.  To this end the candidate will set up biochemical assays for hydrolytic reactions in small emulsion droplets (diameter: 2-20 um) and explore whether (i) these assays can be carried out in such in vitro compartemnts , (ii) whether it is possible to measure kinetics in these droplets oand (iii) carry out directed evolutino experiments with a sreening system of unprecedented capacity. In addition to tehse technical aspects, the candidate will also charcterise the mechanism of the wild type enzyme and its mutants.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Codes And Methods Improvements for VVER comprehensive safety assessment' (CAMIVVER).

assistant: **Concept**

VVER reactors constitute a significant and dynamic part of the European energy market. The safe LTO of VVER (maintenance, refuelling, safety-upgrade, revamping) is based on the industrial use of neutronics and thermal-hydraulics codes and methods that allow studying the behaviour of the plant in normal and accidental conditions. The objective of CAMIVVER project is to develop and improve codes and methods for VVER comprehensive safety assessment.  Such development is strongly required for the following reasons:  1) Current codes and methods used for VVER safety assessment are subjected to international export controls from outside EU. Export controls from major countries have increase in the last years, threatening the EU sovereignty and security in terms of energy supply. 2) A new generation of innovative codes and methods are being developed within Europe. These new codes and methods are improving 3D-multiphysics modelling capabilities, and uncertainty quantification capabilities. These codes and methods are worth being transferred from lab to industry as they will substantially improve the physics comprehension of PWR and VVER behaviour. 3) European codes and methods development for VVER safety assessment will open the VVER market to the European nuclear industry and will support a free and fair competition on this market. To achieve this objective, CAMIVVER will perform developments required for the new generation codes to be fully applied on VVER scope (and to PWR scope too), CAMIVVER will generalise 3D-multiphysics coupling, CAMIVVER will perform experimental validation and benchmark against current industrial codes used for VVER safety assessment, and CAMIVVER will demonstrate CFD utility and compatibility with uncertainty propagation in the frame of a safety ass
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'AdaptAIR: Climate Adaptation through Artificial Ice Reservoirs (AIRs) in the Himalayas', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Shrinking glaciers and more frequent extreme weather events threaten the water security of 55 million people living in the Himalayan Mountain range. Artificial ice reservoirs (AIRs) – annually created stores of ice formed each winter through diverting streams or pumping groundwater into the air – are being rapidly implemented across the northern-most Indian Union Territory of Ladakh. However, the construction of AIRs has been conducted without consideration of the social and environmental context of which they are being placed. This limits the efficacy of AIRs, and mirrors a wider impasse in climate adaptation: critiques provide crucial insights into the limitations and potential harms of new technologies, but lack the required solutions. AdaptAIR combines experts in science and technology studies, critical agrarian studies, anthropology and physical geography to develop a novel framework for implementing AIRs across the Himalayas. This will be achieved through a programme of cross-disciplinary research into the environmental, social, economic and cultural conditions that effect the viability of AIRs in Ladakh. Specifically, we will: (i) understand and contextualise regional climate change in relation to AIRs and livelihoods; (ii) situate AIRs within the cultural and environmental context of glacier recession; (iii) research the hydrological and social impacts of AIRs; (iv) develop and implement a participatory and grounded approach to constructing AIRs. Together, this approach will be used to develop a framework for constructing AIRs across the Himalayas, based on novel theoretical approaches to climate adaptation.


**Keywords:** Agrarian political economy, critical physical geography, historical climatology
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Photogenerated Hydrogen by Organic Catalytic Systems', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Aim of the project “Photogenerated Hydrogen by Organic Catalytic Systems (PHOCS)” is the realization of a new-concept,photoelectrochemical system for hydrogen production, based on the hybrid organic/inorganic and organic/liquid interfaces. PHOCS takes the move from the recent demonstration of reduction/oxidation reactions taking place, under visible light and at zero bias, at the interface of an organic semiconductor and an aqueous electrolyte, obtained by the coordinator’s group.PHOCS intends to combine the visible-light absorption properties of organics, together with the enhanced charge transport capabilities of inorganic semiconductors, in order to build a hybrid photoelectrode for hydrogen generation. New organic donor and acceptor materials (conjugated polymers and fullerenes derivatives) will be synthesized, properly tuning HOMO-LUMO levels position and energy gap extent for semi-water splitting purposes. In order to build properly-working photo-electrochemical cells, issues such as stability, wettability, catalytic functionality, electron transfer processes at the polymer/electrolyte interface will also be faced during the synthesis step. Multifunctional, high surface area, inorganic electrodes will be moreover developed, in order to increase surface area, provide ohmic contact to the organic active layer, 3D control of the donor-acceptor junction and advanced light management. Spectro-electrochemical characterization of organic/inorganic and organic/electrolytic solution interfaces will be continuously performed, in order to deep characterize charge transfer phenomena and improve the device performances. Final aim of PHOCS project is the realization of a scaled-up, 10x10 cm2, 1% solar-to-hydrogen energy conversion efficient device, as a tangible first step towa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Single Metal Atom catalysts electrochemical Reduction of CO2-To-CO (SMART-CO)'.

assistant: **Innovation**

Achieving net zero CO2 emissions requires replacing fossil fuel-derived precursors in the chemical industry, driving the rise of the Power-to-X electrochemical sector. CO2 can be electrochemically reduced into valuable products at cost-competitive prices. Earth abundant single metal atoms coordinated to N-doped C (M-N-C, M = Fe, Ni) can selectively reduce CO2 to CO (an important precursor to Fischer-Tropsch and fermentation), with the same activity and efficiency as current commercially used thick Ag and Au electrode. M-N-C therefore present a cheaper, accessible, and sustainable alternative. However, their practical implementation is restricted by their synthesis bottlenecks, poorly understood CO2 reduction mechanism and long term (≥100 h) degradation at practical current densities (≥200 mA cm-2). To solve these problems, I will introduce automated M-N-C synthesis innovatively adapted from the food industry. State-of-the-art operando NMR will uniquely resolve the metal cation solvation and impact on CO2 reduction, while emerging electrochemical techniques and in-situ X-ray absorption spectroscopy will probe the active site density. I will calculate catalyst lifetimes for the first time, based on the rate of active site loss, and establish catalyst properties limiting stability. I will use these insights to develop an accelerated stress test for M-N-Cs in CO2 electrolysers, facilitating faster screening and establishing a benchmarking tool for academia and industry. Thus, the proposed project will solve the three major challenges of catalyst scalability, selectivity, and stability and would equip me with scientific, technical and managerial skills to become a leading independent researcher in electrochemical technologies. The world-leading M-N-C synthesis, reaction mech
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Molecular interactions during infection' (MIDITRAIN), addressing dissemination and exploitation.

assistant: **Impact**

The global spreading of infectious diseases has become again a major public health problem within and outside of the European region. High quality research aimed at the identification of critical components of host-pathogen interaction is one prerequisite for future development of new efficient tools for the diagnosis, prevention, therapy and control of infectious diseases. Recently, novel technologies and new methods have become available that can be used to address fundamental processes of infection. This has resulted in higher demands on the training and education of early-stage researchers who now have to master classical as well as novel disciplines to be successful in the future. MIDITRAIN is an integrated PhD program that offers highly interdisciplinary training of the early-stage researcher in all areas of infection biology.Training is provided throughi) cutting-edge research projects focussing on molecular interactions of host and pathogen during infection;ii) comprehensive education and intensive tutoring via special practical courses, lecture series and seminars as well as summer schools covering latest concepts, discoveries and methodological approaches within the field;iii) complementary training designed to acquire all skills required for future independent research and leadership in academic research or industry. The training will take place at the National Centre for Biotechnology (GBF) in Braunschweig (Germany) were a unique environment of specialized research groups will provide a combination of expertise in infection biology, genomic, cell biology, biochemistry, structural biology, microbial pathogenesis and bio informatics. The institution has in addition an extensive technological infrastructure with state-of-the-art platform technologies and core f