RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'VAD-Patient interaction: from rest to exercise' in the context of a Seventh Framework call.

assistant: **Objectives**

Heart failure is the first cause of death in industrialized countries. Despite the use of medical therapy a certain percentage of patients (PTs) will progress to end stage heart failure. In this case the ventricular assist device (VAD) is a viable therapy that nowadays is used increasingly not only as a bridge to transplantation, but also as destination therapy and as a bridge to recovery. Therefore, there is a clinical need to understand how to estimate and modulate the optimal level of support (VAD rotational speed) to be provided according to PTs’ activity (resting, standing up, bicycle riding etc).This project is aimed at studying the effects of VAD speed modulation on PTs’ hemodynamics during physical activity (PA) and to compare them with a fixed VAD speed. To this aim clinical data will be acquired before and during VAD implantation surgery. Then two follow-ups will be organized to acquire data on VAD PTs performing different levels of PA at constant vs. manually increased VAD speed. Besides, due to the complexity of the issue involving both cardiovascular and respiratory variables, a computational  cardio–respiratory simulator will be developed. It will be able to reproduce beat-to-beat PTs’ specific hemodynamic and respiratory condition (in terms of heart rate, flows, pressures, O2 and CO2 saturations, vascular resistances etc), at rest and during PA including the effects of VAD support.The present clinical study may contribute to improve VAD therapy with benefits on both PTs’ quality of life and on possible PTs’ improvements/recovery. Besides, the simulator will be a user friendly tool exploitable as a clinical support for VAD therapy optimization and  PTs clinical management improvement.  Moreover the simulator will be exploitable as a training tool for clini
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Robotic embodiment of a meta-learning neural model of human decision-making' under Horizon 2020.

assistant: **Concept**

The combination of empirical testing with computational modeling is the most promising path in neuroscience of decision-making. Nonetheless, neuro-computational models of decision-making are still affected by two main limitations. First, computer simulations, typically used for testing neural models, represent the environment in a very simplistic way, exposing the computational models to “toy problems”. Second, computational neuroscience often neglects that bodily processes do not simply “execute” what is decided centrally, but are part of cognitive processing itself (embodied cognition). The main goal of this project is to solve these two limitations and to open a new path in cognitive and computational neuroscience of decision-making. We plan the embodiment in a humanoid robotic platform (iCub) of a novel neuro-computational model, representing the state of the art in modeling neurobiology of decision-making. This neural model, the Reinforcement Meta-Learner (RML), generates emergent (i.e., homunculus-free) cognitive control signals and supports learning to solve complex decision problems by self-regulating its internal parameters (meta-learning). In simplified and disembodied computer simulations, the RML already revealed to be exceptionally successful in explaining many different experimental data sets (both neural and behavioural) from different domains. The RML embodiment would represent one of the few cases where a neural model, born completely in the domain of cognitive neuroscience, would be embodied in a humanoid robot. The fusion of cognitive neuroscience and humanoid robotics will allow to investigate the role of embodiment in decision-making in real world problems (contribution to neuroscience), and it also would represent a unique opportunity to test the e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'a rapid and efficient method for generation of iPSC' to be submitted under Horizon 2020.

assistant: **Abstract**

The discovery of induced pluripotent stem cells (iPSC) has provided a major advance in biomedical research as they are able to offer meaningful models to investigate human diseases and biology. A growing number of research laboratory are using iPSC for studying a wide variety of human diseases. iPSC have also tremendous potential for regenerative medicine because they can be virtually differentiated in any type of cell. Through the support of the ERC grant IEMTx, we built-up an in-house protocol for generation of iPSC from patients’ cell lines that is efficient and has an extremely low cost compared to other available methods with the highest clinical safety. Therefore, we can offer a superior system to produce iPSC based on a simpler, more efficient, highly reproducible, cost effective and customizable process. Moreover, HDAd have potential also for cell trans-differentiation that is the reprogramming of one somatic cell type into another cell type without passing through the pluripotent state. In summary, the goal of this proposal is to pave the way towards commercialization of our novel products for generating iPSC and trans-differentiated cell lines based on HDAd vectors as non-integrating, high-cloning capacity, inexpensive and easy to use vectors. We believe this method will become a relevant opportunity for biomedical research and might find applications in regenerative medicine as well.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Novel antigen-adjuvant vehicle as an effective influenza vaccine' in the context of a Sixth Framework call.

assistant: **Objectives**

Influenza is a recurrent global threat and affects millions of people in Europe and the world every year. The Universal Vaccine project is highly original and brings together European state-of-the-art scientists in order to develop a powerful new mucosal vaccine for humans providing life-long protection against influenza. In the longer perspective, the project may contribute to the objective of reducing or even eradicating influenza disease in humans.The Universal Vaccine project combines European SMEs and RTD performers that have pioneered the development of new vaccines and vaccine formulations, and which possess unique IPR related to new components and procedures that can be used for safer and more effective vaccination strategies. Arexis (SE) is the IPR holder of CTA1-DD, which is a new highly potent mucosal adjuvant. Pepscan (NL) has unique knowledge and IPR related to peptides and peptidomimetics while Proxima Concepts (UK) has the exclusive IPR related to a proprietary delivery technology. The unique collaboration between these SMEs and VIB/University of Ghent (BE), the IP holder of M2e-based influenza vaccines, Eurogentec (BE) and Göteborg University (SE) has the potential of resulting in important breakthroughs in European vaccine development research.The unique combination of the three SMEs for the rational design of a mucosal influenza vaccine is unprecedented in European vaccine research. A successful novel mucosal vaccine against influenza would have significant impact on the global market and secure the growth and development of the European vaccine industry. If successful, Arexis, Pepscan and Proxima will establish themselves firmly on the market for mucosal vaccines, and their extended and potentially stronger IP would allow for an expansion of their res
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Environmentally adapted pretreatment before powder coating' in the context of a Fourth Framework call.

assistant: **Objectives**

In Europe the building industry (architectural applications) is still dominated by using yellow and green chromating as pretreatment methods of aluminium before powder painting for outdoor use. This is strongly dependent upon the robust processes and a relatively broad process window. Another reason is that the two European organisations GSB (Gtegemeinschaft fur die Stckbeschichtung von Bauteilen) and Qualicoat thus far only has approved chromating, anodisation and recently preliminarily approved two alternatives on architectural details for outdoor use. Chromating accounts for approximately 300 MECU a year in the European building industry and the painted and chromated surface is evaluated to 350 400 Mm/year. However, yellow as well as green chromating contain hexavalent chromium (Cr 6+) both in the baths and in the coatings and this hexavalent state is declared to be very toxic, carcinogen 111 and sensitizing , i e frequent and/or prolonged exposure can lead to allergies. Furthermore Cr 6+ requires heavy waste tretament steps, depending on for instance the reduction to the trivalent chromium state before disposing it. The reduction and disposal costs are about 65 % of the costs of the chromating chemicals. The available chromium free treatments have limited application because of limited long term bath stability and scale up problems (5 months bath life for zirconium based bath, compared with 5 years bath life for a standard chromate bath) and because an objective comparison with standard technology on real products is not available. Moreover the use of rinsing steps results in waste water. The feasibility study in stage 1, with 4 investigated main alternatives, showed promising results in outdoor and accelerated corrosion testing . The main objective of this resear
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'DYNAMIC GUIDANCE SYSTEM', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

This project intends to demonstrate that drillstring and motor steerability can be achieved without the need to stop drillstring rotation (ie. Steerability is not dependent on mud motors but motor performance can be enhanced by this technology).To show also that current downhole technology can be applied in a different and significantly more efficient manner.Consequently, greater advantage still can be achieved in the form of automated and interactive control systems for downhole drilling equipment.All ongoing objectives have been met.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Belgian researchers initiative to heat that Night' under Sixth Framework.

assistant: **Concept**

On the 22nd of September 2006, five big events will be organised in four Belgian cities in the Frame of the European Researchers' night. 7 partners have joined their forces in a consortium coordinated by the Belgian Federal Science Policy (belspo), including 4 of the biggest Belgian Universities, 4 Federal scientific Institute merged for the occasion in a unique Space Pole and one High School.All partners agreed on a common publicity campaign, a common communication and last but not least; a common basic activity consisting of a photographies exhibition completed with an original audiovisual show. Next to this; freedom has been given to the partners, so the Belgian researchers' night will be the unique opportunity to see men feeding sharks, a science fiction movies in Kortrijk; a Jazz concert in Louvain la neuve, a unique base ball game at the Planetarium, and a unique event in the centre of the Brussels' night life.The main message that the organisers intend to communicate is that researchers are people like you and me, and it is in this way that all the audiovisual supports will be directed. After that evening, researchers will be considered much closer from the audience, having as consequence that research and science can be envisageable for a future career.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Rehabilitation and revegetation of mining waste-dumps by the use of industrial and domestic sewage sludges from waste-water purification plants' (1994-1998).

assistant: **Concept**

Objectives and content:The utilisation of waste as secondary raw material is a fundamental principle of the so called sustainable development, world-wide. Prerequisite for the usage of pollutant bearing materials is that a negative impact on the environment can be excluded. Waste dumps resulting from open-cast and underground mining operations constitute a serious environmental problem if they are not properly rehabilitated and regenerated, because untreated dump-sites form a source of continuous emission of dust, fumes and a source of possible ground-water pollution. One significant cost-factor of the rehabilitation results from the necessity of purchasing soils, if in situ soil is not available. This cost-factor could be substantially reduced by using the positive physical, chemical and biological properties of mixtures based upon industrial residues (fly ash from power stations, red mud from alumina production, flotationtailings) and sewage sludges as a fertile component. Capping the waste dumps and at the same time create a fertile substratum for revegetation can contribute to the solution of safe disposal/utilisation of industrial residues and rehabilitation of waste dumps resulting from the mining industry. Additionally the usages of these residues as secondary raw material save natural resources and avoid the demand of disposal-site volume.Sludges, especially sewage sludges and industrial waste contain a large number of different potential contaminants, which causes environmental problems. This requires a methodology to deposit the artificial topsoil in place and mix it with the upper most layer of the waste dump and to prevent the toxic components of the mixture from being leached out of the soil. As a basic research project, the research aims at developing the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Futuring Peace: the Politics of Water Conflict in a Post-truth Age' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The international peace and security architecture is undergoing urgent change to accommodate a conflict environment that will be increasingly shaped by the quality of environmental governance in a context of climate change. Water problems  with its associated drought, wild fires and flooding  are at the centre of changing conflict dynamics. The 2021 Report of the Independent Panel on Climate Change (IPCC) devoted 200 pages to this issue alone, highlighting the vulnerability of weak states and agricultural communities within them to water conflict stemming from poor regulation of access to scarce resources. In addition to a rise in water conflict, peace and security policy and practice is also adjusting to a global context of rapid technological, geo-political and normative change. Climate change and advances in techno-science are intricately linked in the UNs Futuring Peace initiative, which explores the possibility of using big data, machine learning and social media to inform climate conflict prevention activities . The digital expansion of public space has also facilitated post-truth politics, which denotes the use of digital technologies by rising illiberal authoritarian and populist powers to question or fabricate scientific facts about global issues, including both climate change and military conflict . Climate conflict narratives have placed peacebuilding practice between the objective truth claims of big data and the ontological condition of ambiguity  or multitude of truths regarding climate-conflict risk. This project will focus on how the inter-related issues of climate change, technology, rising illiberal global powers and post-truth politics cohere around water resources to influence conflict dynamics and the norms that underpin international peace and secu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Evolution in Security and Privacy for 6G networks' in the context of a Horizon Europe call.

assistant: **Objectives**

ENSURE-6G project will develop robust solutions to provide resilient 6G telecommunication infrastructure in the presence of both cyber and physical attacks in 6G networks. The rationale for the ENSURE-6G project is well justified due to the need for advanced and intelligent security and privacy-enhancing mechanisms deployed in practice within current mobile networks and the necessity of novel efficient mechanisms for future networks. ENSURE-6G will have a strong impact on the careers of all participating staff involved. It will equip them with cutting-edge technical and practical knowledge in the security and privacy of 6G technologies. It will create an opportunity to build a strong professional network and bond with industry partners beyond the project’s completion date. The ENSURE-6G will aim to ensure that the EU is at the forefront of security and privacy requirements of 6G networks and that new security measures are designed to mitigate the risks associated with new 6G end user devices and users.


**Keywords:** 6G, Security, Privacy, Federated Learning, Ethics, Future Networks, Mobile Networks
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Personalised Image-based Computational Modelling Framework to Forecast Prostate Cancer' (PICModForPCa), addressing dissemination and exploitation.

assistant: **Impact**

Prostate cancer (PCa) is a major health problem among ageing men worldwide, especially in Europe. However, the medical management of PCa only offers limited individualisation and has led to significant overtreatment and undertreatment, which may compromise patient quality of life and survival respectively. Active surveillance is a clinical strategy in which patients with life-threatening PCa are directed to treatment while those with indolent tumours remain closely monitored via regular clinical tests and medical imaging. Multiparametric magnetic resonance imaging (mpMRI) provides high-quality data on PCa and is increasingly used in its diagnosis and surveillance, but computationally exploiting the wealth of data in these images to obtain precise information on tumour evolution to guide clinical management is an unresolved challenge. To address this timely issue, this project proposes to derive a personalised predictive mathematical model of PCa based on mpMRI to run organ-scale simulations that improve diagnosis and forecast the patient’s tumour evolution. The model will rely on robust biological and mechanical phenomena described via differential equations whose parameters are identified voxel-wise by solving an inverse problem using the patient’s clinical and mpMRI data at two dates. The model will then be validated by comparing simulation and actual data at a posterior date. The resulting predictive technology offers an unparalleled advance to personalise and optimise active surveillance for PCa, hence meeting many European Commission priorities for research in cancer.The candidate has previously developed computational models and methods to study PCa growth in clinical scenarios. Building on this ideal background, this project will provide him with crucial scientif