RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Advanced near field optical tools with biochemical functional recognition at the single molecular level' (2002-2006).

assistant: **Concept**

In this proposal we aim at developing truly novel optical scanning probe tools to allow nanometric local probing, interrogation, manipulation and dissection of biological function at the level of single molecules in their native environment: the living cell. Our objectives are two-fold: First, to pioneer the development of a novel multi-parameter scanning probe microscope able to provide for the first time simultaneous topographic, optical and biochemical recognition in one and the same instrument. Second, we will exploit the newly devised technology to unravel the organisation and dynamics of the cell surface receptor landscape at the nanometre scale in relation to cell function.As such, the proposal is fully compatible with the NEST-ADVENTURE objectives since the research is focussed on the development of an entirely new technology which, if successful, will not only open up new avenues for progress in fundamental and applied sciences but also for biotech- and high tech instrumentation- industry. Furthermore, it has a high risk character since we will attempt to enter into an uncharted territory combining areas of nano-instrumentation, nano-photonics and nanometre scale biology. In order to maximise the chances of success we have chosen for an interdisciplinary, trans-national and multi-institutional (research institutions, high education centres and industry) partnership. Thus, our working strategy will rely on the strong cooperation between the different partners, which as added value will also lead to a strengthening of cohesion in European research. In the long term we expect that both, fundamental researchers (material science, surface chemistry) as well as industrial sectors (nano-technology enterprises and the biotechnology and pharmaceutical industries) will b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Teaming to Upgrade Excellence in Environmental Biology, Ecosystem Research and AgroBiodiversity' in the context of a Horizon 2020 call.

assistant: **Objectives**

The overall and long term goal of BIOPOLIS proposal is to upgrade ICETA-CIBIO (Research Centre in Biodiversity and Genetic Resources), a Research Unit in the field of biological sciences from a low-performing Member State (Portugal), to a Centre of Excellence (CoE) for R&D&I in Basic and Environmental Biology, Ecosystem Monitoring and AgroBiodiversity, through the TEAMING with Porto Business School (PBS) and the University of Montpellier (UM), an institution of research and innovation excellence from an advanced performing Member State (France). The proposal builds on the rising performance of ICETA-CIBIO over the last decade, which has been significantly boosted by a FP7 CAPACITIES Project funding the installation of a Next-Gen Sequencing Platform, and the award in 2015 of an H2020 ERA Chair. The proposal also builds on a formal working relationship between ICETA-CIBIO and UM established in 2014 through a Laboratoire International Associé (LIA), supported by FCT (Portugal) and CNRS (France). Based on these previous achievements and collaboration experience, ICETA-CIBIO, PBS and UM produced in this TEAMING phase 1 proposal a consistent and streamlined work program to prepare the operational plans for BIOPOLIS, by (i) establishing the communication, dissemination and exploitation strategies; (ii) strengthening relationships with public and private stakeholders; (iii) establishing a research program; (iv) evaluating needs, costs and funding opportunities; and (iv) developing a business plan. The proposal was designed to harness the unique atmosphere of Excellence Towards Innovation existent in the R&D&I ecosystem of Montpellier. This will be used to effectively promote the upgrading of ICETA-CIBIO and foster the development of cutting-edge research, and its downstream app
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Fundamental Physics at the Low Background Frontier' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The nature of dark matter is one of the fundamental questions in physics today.  Direct signals for dark matter have remained elusive, indicating that multi-tonne scale detectors are needed to measure large numbers of dark matter interactions, while current efforts are at the 100 kg scale.  The foremost challenge is distinguishing dark matter signals from backgrounds, the most uncertain of which are from neutrons.  The research objective of this proposal is a world-leading dark matter search with a novel liquid argon (LAr) detector and a new analysis approach to measuring neutron backgrounds in-situ.The DEAP/CLEAN program of single-phase LAr detectors is a new direction for dark matter searches.  It draws on successful, proven approaches of solar neutrino physics to building low-background detectors that scale simply to multi-tonne target masses.  Demonstration of this approach by the current 100 kg stage (MiniCLEAN) will break new ground for future experiments.  At the 100 tonne scale, such a detector would be a new kind of observatory for fundamental physics at the low background frontier, testing predicted properties of dark matter, neutrinos, supernovae, and stellar evolution.  Success depends critically on demonstrating the required background suppression.This proposal addresses the key challenges of dark matter detection in two new ways, with the novel single-phase effort for multi-tonne scalability, and by developing new methods to overcome neutron backgrounds.  The tasks of this proposal are: (i) to develop a measurement of the in-situ neutron background in LAr; (ii) to develop an active neutron veto for in-situ measurement of the cosmogenic neutron background, beginning with a measurement of the flux and energy spectrum in an existing prototype; and, (iii) to l
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'From hands to concepts: evolutionary and developmental origins of gesture iconicity' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

The GESTICO project will explore the developmental and evolutionary origins of gestural iconicity, by examining the spatial properties of gestures that convey meaning independently of semantic communication. The relevance of different amplitudes and lateralisation of gestures in reference to spatio-numerical and/or emotional magnitudes will be tested in non-human primates (Chimpanzees, Bonobos, Guinea baboons, and Barbary macaques) and preverbal human infants. Observational data from chimpanzees and bonobos will be used to investigate whether the amplitude and laterality of their communicative gestures are meaningful, by testing their correlation with specific social or emotional contexts, and whether they impact the responses of recipients (WP1). Movement analyses, based on newly developed deep learning tools, will be used to enable quantitative measures on gestures. Once the methodology of gesture spatialisation description is established for great apes, similar analyses will be applied to gestures of captive Guinea baboons and Barbary macaques (WP2). Finally, a habituation paradigm measuring looking times will assess the ability of human infants aged 10 to 12 months to spontaneously associate concepts of magnitude (quantities) with metaphorical manual gestures differing in their spatial amplitude (WP3).Collaboration between the host organisation, the Wild Minds Lab (University of St Andrews), the Eco-Anthropology Lab (French National Museum of Natural History), and the Integrative Neuroscience and Cognition Center (Paris Cité University) will facilitate an interdisciplinary approach, enabling cross-species comparisons around common concepts. The complementary use of innovative observational and experimental approaches will contribute to a better understanding of the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Federated cybeR-physical infrastructure for ODD cOntinuity' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

The operational context is the cornerstone to ensure performance and safety of CCAM. The ODD, by design, defines the operating environment for which a system is designed for. On the other hand, Authorities and Road Operators are responsible for operating the PDI with a variety of vehicles and systems with limited knowledge on the diverse ODD specifications. To answer the question of how safe is a CCAM service, one should not only address the ODD used for shaping the functional boundaries of CCAM (top down), but also the infrastructure, system related, safe and secure communications related and conditions (traffic, weather, hazards) related aspects of the road environment these systems will operate (bottom up). The grande challenge is to design broader ODDs that allow for cooperation with the PDI in a safe system design framework; the industry cannot unilaterally develop and operate sustainable and robust ODDs without the feedback from Authorities and Operators. Future ODDs should be designed with many redundancies (fail safe design) to allow for increased tolerance to vehicle- and context-specific capabilities and human errors and cooperate with physical and digital road infrastructure to boost proactive safety; Seamless, safe and secure physical and digital environments must coexist and collaborate to allow for the appropriate levels of data, information and decisions flow. FRODDO’s vision is a future of robust, safe, secure and seamless connectivity and automation that can adapt to physical, technological and social challenges and support user centric mobility and development. FRODDO’s overarching aim is to develop and test a complete suite of methods and tools based on the principles of safe systems design in a federated DT environment leveraging advanced sensing, ML
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'DIagnostic NAnotech and MICrotech Sensors', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

DINAMICS aims to promote the uptake of nano-technological approaches by developing an integrated cost-effective nano-biological sensor for detection of bioterrorism and environmental assays. The prime deliverable is an exploitable lab-on-a-chip device for detection of pathogens in water using on-the-spot recognition and detection based on the nano-technological assembly of unlabelled DNA.DINAMICS will integrate DNA hybridisation sensors with micro-fluidics and signal conditioning/processing both on silicon and polymer substrates avoiding the use of external apparatus for fluid handling, electrical signal generation and processing, based on DNA hybridisation. A sensory breakthrough will be achieved trough two complementary technological solutions: Measurements based on electrical (capacitive) signals. If hybridisation occurs between target and probe the detected change can be functionalised. Detection through UV light absorption. Based on the recognition of different UV absorptions induced by DNA hybridisation.The development of a system where each sensing site in the micro-array contains a UV micro-fabricated sensor is a goal of the project. After DNA hybridisation the whole array is illuminated with UV light and the absorption of each site is measured by the sensor. The project will culminate in an integrated multi-technology product that will be high tech, low cost and time efficient sensing device applicable for use in the water industry via the coordination of nano and bio technologies with new sensory science to deliver a product that will lead to major changes in the way the testing and diagnostics of harmful substances is done. Both methodologies will ensure an additional and reliable source of cost-reduction through a drastic shortening of the sensing pipeline a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The economic, social and political consequences of democratic reforms. A quantitative and qualitative comparative analysis' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The latter part of the twentieth century was a period of rapid democratisation on a global scale. The attention of comparative politics scholars followed the progression of so-called Third Wave democracies, and gradually progressed from the study of the causes of and the transitions to democracy to the problems of democratic consolidation, and then to more recent issues relating to the  quality  of democracy. A further, frontier step may now be added to such research path by focusing on a subject that has remained largely under-researched, if at all, namely the political, social and economic consequences that emerged in countries where real democratic change took place. The question of what democracy has been able to deliver will become ever more relevant to the future prospects of recent democratisation processes and of democracy at large.In the study of the consequences of democratisation, the advent of democracy is thus no longer observed as an endpoint, or a dependent variable to be explained, but as a starting point, or an independent variable that allegedly contributes to the explanation of a wide range of political, economic and social effects. The question of the corollaries of democratisation also has crucial policy implications.The goals of the proposed research are:a) the definition of a theoretical framework that articulates, integrates and interrelates the different existing hypotheses and arguments on the consequences of democratization processesb) the empirical investigation, through a combination and integration of quantitative and qualitative methods, of the validity of three specific such hypotheses, namely:i. democratisation favours the consolidation of the state (as a political effect)ii. democratisation favours economic liberalization (as an economi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Development of a nanotechnology-based innovative assay for the diagnosis of allergy to Betalactams' (ASSERT).

assistant: **Concept**

Betalactams (BL) are the most widely used antibiotics and the first-choice drugs to control several bacterial infections, however, they can lead to serious allergic reactions in up to 10% of the general population. The current diagnosis of allergy to BL includes skin test and/or drug provocation tests, which are invasive and carry a risk of anaphylaxis requiring hospitalisation. Basophil activation test (BAT) is one of the best options for diagnosis of allergy because it is free of risk and at a reduced cost for health care. The ASSERT project will bring a nanotechnology-based BAT assay specific for allergy to BL with higher sensitivity and specificity, which are the main weakness of the current assays. Of importance, the number and conformation of displayed antigens  at the nanoparticle surface will be controlled to assure standardisation and increase precision and reproducibility of the assay. In addition, a complete validation plan is envisaged to fit the standards for clinical diagnostics. The two factors for the success of the project are, one one hand, the solid experience of the host lab in immunology, specially allergy and nanoparticle technology and, on the other hand, the expertise of the candidate in immunology, molecular biology and test validation design for clinical diagnostics. Moreover, the the two way of transfer of knowledge is assured, which will help the candidate to restart her research career in the European Union. Finally, the expected results of the project will contribute to enlarge the basic knowledge about allergen-specific activation of basophils, and will give rise to an optimised BL-BAT assay with the required clinical and analytical validation to be used in diagnostics.


**Keywords:** Betalactams, Allergy, Basophil activation test, Nannop
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Spectral synthesis of multidimensional supernova explosion models' (SNSM).

assistant: **Innovation**

Core-collapse supernovae are the explosive deaths of massive stars. Theyare the main production sites of the heavy elements in the Universe, drive galactic dynamic and chemical evolution, and produce exotic remnants such as black holes and neutron stars. To interpret observations and advance our understanding of the origin of the elements, sophisticated spectralmodels are needed. The main science objective in this proposal is to computethe first spectral models of multi-dimensional core-collapse explosion simulations. These models will then be compared with available high-quality data to derive information on nucleosynthesis yields and supernova structure. The proposed work involves the development of spectral modelling tools from current 1D to multi-D capability, and application of these to recently computed state-of-the-art 3D explosion simulations.This innovative project will allow a milestone in supernova research to be reachedby producing the first light curves and spectra of modern 3D simulations,and will approach us to solving an almost 50 year standing mystery of how supernovae explode and how the elements are produced.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Illes Balears INNOvation Management Services'.

assistant: **Innovation**

The overall IB INNO project objective is the establishment of a feasible and effective service for enhancing the innovation management capacity of SMEs in the Balearic Islands region. This will benefit the smart growth in the European Union by increasing the efficiency and effectiveness of investments in research, development and innovation and by contributing to a better and more efficient connection of stakeholders in the innovationfabric.In order to realize this objective, the core actions are broken down as follows:• Help SMEs to sustainable high growth through innovation.• Achieve tangible managerial transformation.• Improve the commercial potential of SMEs.IB INNO will act as access point to the innovation and internationalization system in the Balearic Islands region, which will be in this new period covered by Balearic Islands Enterprise Network B2EN consortium, embedding the EEN innovation services in the regional innovation ecosystem.


**Keywords:** innovation management, growth, internationalization, capacity building, SME instrument