RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Flexible chemical looping combustion for combined heat and power production from biogenic residues with negative emission'.

assistant: **Innovation**

CHP plants are burdened with significant economic risks when investing in Carbon Capture and Storage (CCS), due to the high cost and energy penalty of CCS. Switching the feedstock from fossil fuels to biomass can significantly reduce the overall CO2 emission; however, it is essential to develop CHP technologies that can utilize low-value biogenic residues and wastes to avoid an increase in the cost of utility. In addition, coupling a bio-CHP plant with CCS results in negative CO2 emissions which is fundamental to many scenarios to reach the net zero emission targets.The Bio-FlexCLC project develops and demonstrates a novel flexible technology for CHP plants at TRL 5 to utilize low-value biogenic residues as feedstock for heat and power production with negative CO2 emissions. Bio-FlexCLC combines the break-through chemical-looping combustion (CLC) technology with conventional circulating fluidized bed (CFB) boilers. The concept is flexible to switch between CLC-CFB modes. Bio-FlexCLC operating in CLC mode has inherent CO2 capture at a low cost and without energy penalty. Bio-FlexCLC utilizes biogenic residues and wastes, improves conversion efficiencies, achieves negative CO2 emissions, reduces SOx and NOx emissions, enhances CO2 capture efficiency at a considerably reduced cost, has flexibility towards load demand fluctuations, and the capacity to switch to CFB combustion if market conditions are not amiable for carbon capture or if there is difficulty in the operation to decreases the risk of implement.  Bio-FlexCLC is supported by an expert consortium to ensure the quality of research and appropriate exploitation. The academic partners in the consortium are leading institutions in the areas of CLC and CFB boilers. The industrial partners are technology providers of bo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Safe, sustainable, lIghtwEight and high-perfoRmance Ni-Rich NMC battery pack with Advanced cell-to-pack monitoring for decarbonising heavy-duty vehicles'.

assistant: **Concept**

In the HDV market, the main considerations for battery packs are safety, durability and mass energy density. High-energy NMC cells are very appealing for achieving the target for future battery packs. However, further developments are needed for high-energy NMC battery packs to meet the stringent safety and durability standards of the HDV market. Additional factor to achieve high mass energy density is reducing the weight of the battery pack, but lightweight structures are less common in HDV due to safety and durability constraints. To respond to these challenges, SIERRA project will develop a safe, sustainable, lightweight and high-performance Ni-rich NMC battery pack with advanced cell-to-pack monitoring for decarbonising HDV. SIERRA project will propose several innovations: 1 - Multiscale modelling of the battery pack to propose compact pack design and to simulate its thermal and mechanical behaviour; 2 - One-shot manufacturing of lightweight multimaterials casings with low environment impact; 3 - Mutli-scale advanced monitoring (SHM, thermal mapping, SoC, SoH) and reduction of the complexity of BMS architecture; 4 - Full integrated cooling system and printed busbars to respond to fast charging requirements and increase performance over the complete operational conditions. The specific use case targeted by the project is the bus market, and SIERRA battery pack will be validated at TRL6 for this market. The integration into the vehicle will be simulated using a digital twin. All SIERRA activities will follow the methodology defined by the SSbD framework. SIERRA consortium is composed of 11 partners (+60% industrials), all with exceptional R&D platforms and proven track records. SIERRA battery pack sales are projected to generate a total cash flow of €87 million betwee
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Enabling an Intelligent Natural Language Based Hub for the Deployment of Advanced Semantically Enriched Multi-channel Mass-scale Online Public Services'.

assistant: **Innovation**

HOPS is a three-year project focused on the deployment of advanced ICT voice-enabled front-end public platforms" in Europe permitting access for European citizens to their nearest Public Administration.The main objective is to address the mass-scale deployment of new online public services support and accessible by voice channels (basically phone, both fixed and mobile), the most accessible a communication means used by European Citizens. This will only be possible by the addition of new fully functional advanced technologies enabling to deliver automated services without losing a quality and even more enhancing the current functionalities even more.In this respect, the project is based on the integration of voice technologies (ASR, Automatic Speech Recognition - TTS, Text to Speech) with Natural Language Process technologies, complemented by Public Administration sector-specific implementation of Semantic Web Technologies.The overall approach follows a systemic structure, aimed to produce fully functional prototypes, which will be tested and validated by the three Local Authorities involved in the project. As a natural extension, the overall architecture will also be able to support additional non-voice channels, having access to the Natural Language Processing and Semantic Web dimensions.The proposal aims to be funded within the Sixth Framework Programme's 'Networked businesses an governments' thematic priority (point 2.3.1.9 in the work programme) and 'Semantic-enabled system and services' (point 2.3.1.7 in the work programme).The proposal is based on previous experiences and partial implementations as executed by the partners involved, and intends to cross-fertilize this already gathered experience by the use of be practices sharing mechanisms suited to deliver and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Integrative Analysis of Gene Functions in Cellular and Animal Models of Pancreatic Cancer', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Cancers are genetic disease arising from the accumulation of multiple molecular alterations in affected cells. Large-scale genomic, transcriptomic and proteomic analyses have established comprehensive catalogues of molecules which are altered in their structure and/or abundance in malignant tumors as compared to healthy tissues. Far less developed are concepts and methods to integrate data from different sources and to directly interrogate gene functions on a large scale in order to differentiate “driver” alterations, which directly contribute to tumor progression, from indolent “passenger” alterations. As a consequence, examples of successful translation of knowledge generated from “omics” approaches into novel clinical concepts and applications are scarce.Pancreatic cancer is a prime example of this dilemma. Representing the 4th to 5th most common cause of cancer related deaths, it is a disease with a major socioeconomic impact. Despite enormous advances in the identification of molecular changes associated with the disease, new treatment options have not emerged. Thus, 5-year survival rates remain unchanged at a dismal 6%, the lowest for all solid tumors.Using pancreatic cancer as a model disease, the goal of this integrative project is to develop novel cellular and animal models, as well as novel strategies to generate, analyze and integrate large scale metabolic and transcriptomic data from these models, in order to systematically characterize and validate novel targets for therapeutic intervention. In addition to the general tumor cell population, special consideration will be given to sub-populations of tumor-initiating cells, a.k.a. tumor stem cells.To this end, the consortium comprises i) SMEs with strong focus on technology development, ii) clinical and academ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Understanding degradation mechanisms of metallic materials in extreme environments using element-resolved electrochemistry' under Horizon Europe.

assistant: **Concept**

Evaluating and fabricating sustainable materials for the energy sector is crucial in addressing the current energy crisis and climate change. Despite safety and sustainability concerns, especially as the early generations of nuclear power plants (NPP) near the end of their operational lifespans, NPPs produce almost one-fifth of the world’s electrical energy. However, controlling material degradation and reprocessing issues in NPPs remains surprisingly understudied due to the extreme operating conditions. Up to 95% of uranium from spent nuclear fuel can be recycled through reprocessing in concentrated nitric acid at temperatures exceeding 100°C, although the underlying mechanisms and the role of alloying elements in the fuel container are not yet well understood.Electrochemical methods have been applied in these extreme electrolytes to investigate materials degradation mechanisms providing in situ global responses. However, these methods are limited as they rely on assumptions developed in aqueous media and do not provide direct, element-specific information, necessitating complementary ex situ surface characterizations. To bridge the gap, the URANUS project will develop a novel element-resolved electrochemistry setup for extreme electrolytes, leveraging the unique expertise of the PI in this field.Element-by-element degradation mechanisms of metallic materials in concentrated nitric acid will be elucidated for the first time, tracking the fate of each alloying element. Other non-aqueous electrolytes including molten salt systems will also be investigated with this approach. This will open new avenues for controlling the corrosion of materials in the energy sector. The unique element-resolved database generated from this project will serve as input parameters for trainin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Dynamic mapping of epigenetic regulation during embryogenesis using in vitro stem cell model', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

This proposal aims to decipher the dynamic regulatory landscapes of chromatin modifiers during embryogenesis. In particular, I envision to unravel their mechanism of action at unprecedented resolution using single-cell based techniques, and provide novel insights on the molecular deregulation that leads to diseases such as cancer. The originality of this approach is to simultaneously address the function of hundreds of chromatin modifiers in early development by using a higher throughput, stem cells-based in vitro screen. In order to achieve this, we will take advantage of a recently established culture system that faithfully recapitulates embryonic development up to somitogenesis in the dish. The combination of various cutting-edge techniques with this model (Cas9-based screening, targeted protein degradation, low input CUT&RUN and single cell RNA-seq) and our sophisticated computational strategies will allow a precise understanding of how various chromatin regulators act on specific targets in individual cell. In particular, we will resolve gaps of how two essential, global modifiers, Polycomb repressive complex 1 and 2, cooperate to regulate distinct cell identity decisions. Ultimately, we will hope to reconstruct the hierarchal dynamics of chromatin regulators at a temporal and spatial resolution of single cells through embryogenesis. The result of this action will be shared with scientific community by open-access peer-reviewed journals, conferences, analytic codes and sequencing data; and with general public through Open Science Days. The Meissner laboratory will provide the ideal environment not only to carry out this project, but also expand my scientific expertise and train my skills to better prepare me to become an independent group leader in the future.


**
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'PAST & FUTURE MILLET FOODWAYS' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Crop diversification critically mitigates agricultural risk for humanity. Identifying the environmental and cultural factors influencing the adoption and abandonment of staple foods through time is essential to an informed discussion about present-day food security and adaptation to a changing global climate. Past studies on ancient agriculture have identified the routes and timing of primary crop dispersals, but we possess a remarkably narrow understanding on how and why new foods were integrated and later abandoned by societies, and why certain crops remained restricted to distinct geographical regions.The MILWAYS project is perfectly poised to fill this alarming gap in knowledge, though a multi-faceted investigation of a specific crop - broomcorn millet (Panicum miliaceum) - which, due to its unique biochemical properties, is traceable across space and time. Making use of multi-disciplinary cutting edge research methodologies, MILWAYS will bridge a large geographic territory and track the earliest millet dispersals across eastern-central Europe from the mid. 2nd mill. BCE onwards all the way to past millet cultivation limit. MILWAYS will utilize the high carbon isotope values of millet, resulting from its C4-photosynthetic pathway in conjunction with the distinct miliacin biomarker in order to identify its consumption, with respect to shifting climates, human mobility, demographic categories of sex, age and changes of plant use across historical times. Along with transforming the approaches on how we study past agriculture, MILWAYS will: a) Identify the interplay of cultural versus climatic factors in past staple food adoption and abandonment; b) Develop novel methodologies to the study of past diets and climates that are highly transferable to the study of other cro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Relativistic calculation of electric and magnetic properties of molecules'.

assistant: **Concept**

The proposed research concerns the development of relativistic quantum mechanical methods for the calculation of electric and magnetic properties of molecules. A relativistic approach is of crucial importance in treatment of molecules that contain heavy atoms. The electrons will obtain very high kinetic energies due to the steep Coulomb potential near these nuclei and their motion should either be described in a relativistic framework or the results should be confected for so-called relativistic effects. We plan to set up a novel method that does the former, using relativistic theory from the outset. This is done by defining the second-quantized electronic Hamiltonian in tenns of relativistic Dirac-Fock (MC)SCF spinors. In this project we will first focus on the formulation and implementation of a 4-component relativistic second-order polarization propagator method. Extension of our methods for relativistic configuration interaction and coupled cluster calculations is also planned.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Dissection of the metabolic grid of IAOx, a precursor for natural plant products and the plant hormone auxin' under Sixth Framework.

assistant: **Concept**

Cruciferous plants, which include the economically important Brassica vegetables and the model plant Arabidopsis, produce indole glucosinolates and indole alkaloids. These bioactive natural products are known to confer specific pest resistance to crucifer plants. For humans, the compounds are known as flavour compounds, cancer-preventive compounds, and biopesticides. Indole-3-acetaldoxime (IAOx) is an intermediate in biosynthesis of indole glucosinolates and indole alkaloids, and is a precursor for the plant hormone indole-3-acetic acid (IAA), that is essential in many aspects of plant growth and development, although its biosynthesis remains elusive, despite substantial efforts.   Recently, it was shown that camalexin (the indole alkaloid of Arabidopsis) was synthesized directly from IAOx, and that several aUhigh-auxina mutants in Arabidopsis obtained their phenotype due to blockage of the glucosinolate pathway downstream from IAOx. The emerging knowledge of IAOx metabolism has unravelled a new exciting area on the borderline between primary and secondary metabolism.   This project will combine bioinformatics with state-of-the-art technologies for gene discovery in the biosynthesis of IAA and camalexin, areas where Europe traditionally has been at the forefront. The inter- and multidisciplinary project is expected to generate biotechnological tools for improving plant resistance and performance, nutritional quality of plant-derived products, as well as for producing high-value compounds in microorganisms.   The project involves attraction of a top-class young Chinese scientist to an internationally leading Community lab, followed by a reintegration phase where the acquired high level scientific and managerial competence will be implemented to advance research in natura
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Safe Data Enabled Economic Development' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

As privacy and trust remain key in the data sharing debate, Privacy enhancing technologies (PET) will play a prominent role by 2025. Safe-DEED takes a highly interdisciplinary approach, bringing together partners from cryptography, data science, business innovation, and legal domain to  focus on improving Security technologies, improving trust as well as on the diffusion of Privacy enhancing technologies to keep up pace with global macrotrends and the data economy, to enable the fastest possible growth. Furthermore, as it has been recently shown that even among large companies, many have no data valuation process in place, Safe-DEED provides a set of tools to facilitate the assessment of data value, thus incentivising data owners to make use of the scalable cryptographic protocols developed in Safe-DEED to create value for their companies and their clients.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'From one closed door to another: Cumulative discrimination and prejudice against marginalised groups in Europe' (EQUALSTRENGTH).

assistant: **Innovation**

The main contribution of EqualStrength is to investigate cumulative and structural forms of discrimination, outgroup prejudice and hate crimes against ethnic, racial and religious minorities from a cross-setting and intersectional perspective. We deploy innovative, targetted and effective methods, which include field experiments, population-level secondary survey data, meso-level policy analysis and targeted data collection to include the perspective of minority groups who directly confront discrimination. Our approach allows us to meet five interrelated research objectives: First, we reveal structural and cumulative forms of ethnic and racial discrimination in Europe, focusing on the experience of Muslim, Roma and Black minorities. Second, we assess the systemic nature of prejudice across life domains, targetting anti-Muslim, anti-Black and anti-Roma attitudes. Third, we analyse policy and institutional factors that contribute to structural discrimination and prejudices. Fourth, we document the lived experiences and coping strategies adopted to confront everyday discrimination. And finally, we highlight the intersection of race, ethnicity and religion with other dimensions of inequality such as gender, sexual orientation, and socioeconomic position. In meeting these objectives, we promise three key contributions: First, we shift the paradigm, moving from a focus on individuals at risk to a family perspective. Second, we reveal cumulative, structural and intersectional disadvantage, pushing beyond setting-specific and single-group discrimination. Third, we provide a multi-actor and multi-level perspective that simultaneously considers multiple actors (i.e. gatekeepers; ethnic, racial and religious minorities; majority groups) and levels of analysis (i.e. the micro-level