RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Movement restoration with Adaptive EEG And Immersive Neurofeedback' (MoveAGAIN) under Horizon 2020.

assistant: **Objectives**

Despite very extensive efforts to help millions of people in the EU alone who seek therapy to improve motor function after a stroke, most stroke patients are left with lifelong motor disability. Recent work from our group and others has shown that new methods and devices that can noninvasively monitor and stimulate brain activity could substantially improve recovery. EEG data collected from portable electrode caps can detect each patient’s motor imagery and thereby influence multimodal feedback in real-time. This feedback may include virtual reality avatars, rewarding music or tones, functional electrical stimulation, and potentially even magnetic or electrical stimulation of motor areas of the cortex. This promising new research direction requires extensive collaboration across disciplines and sectors, and experienced researchers (ERs) with relevant experience. The MoveAGAIN project will explore new classifiers, experimental paradigms, and software in tandem with an existing commercial system to create a new system that will be used to collect data with stroke patients in two real-world settings. We will analyze the resulting data to develop new knowledge and contribute to improved tools that therapists and physicians can use with patients. MoveAGAIN includes extensive dissemination and communication activities to convey our project results to numerous audiences. The varied training activities will supplement the ER’s training-by-research to help prepare him for a high-impact career working across industrial, academic, and medical sectors.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Multiphoton imaging with computational specificity' in the context of a Horizon Europe call.

assistant: **Objectives**

Digital staining based on machine learning models can provide cellular specificity to label-free optical imaging. This concept is particularly interesting for in vivo applications in fundamental research of auto-immune diseases as well as for future clinical translations. In this project “MICS – Multiphoton imaging with computational specificity”, I will develop and implement computational specificity for label-free multiphoton microscopy (MPM) using artificial intelligence (AI). The direct outcome of this project will be two AI modules to perform (i) automated classification of mucosal inflammation based on 3D images from colon tissue and (ii) digital staining of un-stained immune cells. This integration of computational specificity to label-free multiphoton microscopy will allow direct investigation of global tissue alteration as well as specific immune cell localization during inflammatory tissue remodelling. Digital staining is an emerging concept in the field of computational microscopy but has not yet been implemented for immune cells based on label-free MPM images. Building on my previous expertise in label-free in vivo imaging via endomicroscopy, future implementations of multiphoton endomicroscopy would profit from tools for computational specificity, developed during this project.


**Keywords:** Label-free multiphoton microscopy, autofluorescence, machine learning, image classification, digital staining
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Boosting Societal Adaptation and Mental Health in a Rapidly Digitalizing, Post-Pandemic Europe' to be submitted under Horizon Europe.

assistant: **Abstract**

BACKGROUND:Adolescents are at particularly high risk for digital technology overuse, including in response to the COVID pandemic, and are therefore vulnerable for its potential harmful effects on mental health. Problematic usage of the internet (PUI) is thought to represent a marker of disrupted self-management, with major consequences for individual and societal health and wellbeing.AIM: Bootstrap brings together a multidisciplinary consortium aiming to initiate health and social policy and practice change designed to reduce the harmful effects of digitalization on mental health, particularly for young people. APPROACH: We will co-create a digital screening and assessment platform to understand which individuals are at-risk for developing PUI. Algorithm-based models will be used to predict which individual will benefit from which type of self-management intervention, and these preventative behavioral interventions will be tested for their (cost)effectiveness. Finally, we will develop a policy toolkit in co-design with stakeholders, to promote human digital rights accountability at the local, national, and European level.IMPACT:Bootstrap will provide unprecedented scientific knowledge on the psychological mechanisms underlying (risk for) PUI and potential interventions. Improved self-management and tools to optimize healthy internet usage will promote mental health and prevent mental ill health in adolescents, and contribute to reducing stigma. In addition, our policy toolkit will empower policy makers and private companies to (self)regulate with the intent to protect vulnerable groups. In the long run, Bootstrap will thus contribute to improving mental wellbeing across Europe and beyond.


**Keywords:** Problematic usage of the internet; risk assessment; self-managemen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Moduli spaces of local G-shtukas' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

This project provides a novel approach to the local Langlands programme via a comprehensive investigation of local G-shtukas and their moduli spaces and the exploitation of their relations to Shimura varieties.Local G-shtukas are generalisations to arbitrary reductive groups of the local analogue of Drinfeld shtukas. They also are the function field counterpart of p-divisible groups. Hence moduli spaces of local G-shtukas are of great interest, in particular for the geometric realisation of local Langlands correspondences. Compared to p-divisible groups local G-shtukas have several advantages. They can be defined and studied for any reductive group, enabling a systematic use of group theoretic methods and promising unified results. Furthermore, their local description by elements of loop groups makes them more accessible than the description of p-divisible groups by Cartier theory or displays. Comparison theorems to p-divisible groups then provide a novel way to insight into their moduli spaces.The research plan of this project is subdivided into three strands which mutually benefit from each other: Firstly we want to understand the representations realised in the cohomology of moduli spaces of local G-shtukas in connection with the geometric local Langlands programme. Secondly, we study the geometry of the moduli spaces and investigate several natural stratifications.  Finally, we build the bridge to Shimura varieties. On the one hand we explore the source of new results obtained by transferring methods developed for one of the two sides (Shimura varieties resp. moduli spaces of local G-shtukas) to prove similar assertions for the other. On the other hand we establish closer ties by proving direct comparison theorems.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Molecular Simulation: modeling, algorithms and mathematical analysis' in the context of a Seventh Framework call.

assistant: **Objectives**

Many models for materials rely on a microscopic description. In a classical regime and for a fixed temperature, atoms are described by particles that interact through a force field and evolve according to Newton’s equations of motion, with additional stochastic terms to model thermostating. This simulation technique is called molecular dynamics. Applications are ubiquitous, ranging from biology to materials science.The direct numerical simulation of these models is extremely computationally expensive, since the typical timescale at the microscopic level is orders of magnitude smaller than the macroscopic timescales of interest. Many algorithms used by practitioners have not yet been investigated by applied mathematicians. The aim of this proposal is to further develop the mathematical analysis of these methods and to build new and more efficient algorithms, validated by precise error estimates.The underlying theoretical questions are related to the mathematical definition and quantification of metastability for stochastic processes. Metastability refers to the fact that the stochastic process remains trapped in some regions of the configuration space for very long times. Using naive simulations, transitions between these states are very rarely observed, whereas these transition events are actually those which matter at the macroscopic level. Metastability is one of the major bottlenecks in making molecular simulations predictive for real life test cases.The main challenges motivating this proposal are: the design of efficient techniques to sample high-dimensional multimodal measures, the development and analysis of algorithms to sample metastable dynamics and the construction of coarse-graining techniques for high-dimensional problems.This project relies on strong colla
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Long-term performance of candidate materials for HLW / spent fuel disposal containers'.

assistant: **Objectives**

The proposal addresses the qualification of corrosion resistant materials for long- lived HLW/Spent Fuel disposal containers. Such containers as a component of the multi-barrier system will improve the safety in the disposal in geological formations. Based on the findings and recommendations of the previous EU-project the corrosion studies will be concentrated on the most promising container materials such as carbon steel, stainless steels, Ti99.8-Pd, Hastelloy and Cu-Ni alloys.The project will include corrosion studies in rock salt, granite and clay environments. The work will consist of:(i) long-term immersion tests to determine the final corrosion rate of the materials and their susceptibility to local corrosion;(ii) electrochemical studies to examine the corrosion mechanisms and the influence of various parameters on corrosion;(iii) slow strain rate tests to examine the stability of the materials to stress corrosion cracking.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Strengthening the European Research Area in Mediterranean Countries' (ERA-MED).

assistant: **Concept**

It is envisaged that the proposed project will capitalise the investment of EU on the recently establish InPs and achieve the following aims - To realise a mapping exercise of the R Amp D national Programmes in order EC to have a view of national priorities and their possible matching with the participation in FPs. The mapping will to result in a model/prototype database containing the profiles of the key players/organisations involved in the national priorities.- To produce an assessment report on social, cultural and scientific support across the Med. Countries. The InPs will ensure the verification of the data.- To achieve the integration and coherence of InPs into the European networks dedicate to FP7 and to ERA- To establish and implement a promotion/dissemination mechanism in order to keep the Scientists, Researchers and stakeholders of the EU and MPC aware of the possibilities of identifying their counterparts for collaboration in the Research Projects and activities of FP7- To inform and create awareness among EU Scientific communities of the potential added value to be gained by collaborating with their counter parts in Med. Countries.- To prepare the Scientific and Researchers communities in Med. Countries through Thematic workshops which will be well-focused on specific Thematic areas of FP7 according to their needs and priorities. Short updating training seminars to InPs will also be provided.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'NanoTIMER - Nano-technology in mechanical-electrical resonators' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Mechanical resonance is widely applied in high-precision oscillators for a multitude of time-keeping and frequency reference applications. In all such cases, the high-precision resonating element consists of an off-chip passive component, such as a quartz crystal. Major drawback of these off-chip resonator technologies is that they are bulky and must interface with transistor chips at the boards, posing a bottleneck against the ultimate miniaturization of e.g. wireless devices. The extraordinary small size and high level of integration that can be achieved with silicon MEMS resonators appear to open exceptional possibilities for creating miniature-scale precision oscillators to be used in e.g. mobile communication and navigation devices. The aim of the NanoTIMER project is to develop an oscillator with high-accuracy incorporating a silicon MEMS resonator generating frequencies in the 10 to 1500 MHz range.Within the NanoTIMER project, MEMS based oscillators will be realized according to concrete specifications derived from existing applications. The MEMS oscillator will be encapsulated using a wafer-level vacuum package technology that is compatible to the oscillator manufacturing flow. An important feature of the proposed resonator manufacturing process is the realization of nanometre size (100 nm) transduction gaps, which is of prime importance for the realization of MEMS resonators functioning in the GHz range. Reliability and drift of assembled oscillators and its constituent components (resonator and package) will be assessed.The NanoTIMER initiative is a first step towards the realization of 'vibrating' nano-electro- mechanical processors that, combined with traditional CMOS, could open new alternatives for signal processing in VLSI.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Cell mechanics of megakaryocytes in 3D tissues - deciphering mechanobiology of platelet formation', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Homeostatic platelet counts are crucial for vascular integrity and vital to life. Megakaryocytes (MEKs) are giant hematopoietic cells forming large protrusions that fragment to constantly replenish the circulating platelet pool. Nevertheless, severe blood loss, sepsis and aggressive cancer therapies, often cause critically low platelet levels - a major public health problem in Europe's aging population. Despite the unmet clinical need to control platelet production, there is a major lack of knowledge about the mechanistic cell biology of MEKs, hampering the development of innovative therapies.  MEKanics will go beyond the state of the art and proposes a combined cell biological and biophysical approach to study MEKs in physiological tissue environments to uncover the mechanical principles that drive platelet formation. I will use quantitative microscopy to characterize cytoskeletal dynamics of MEKs confined in 3D environments of controlled adhesiveness, geometry and stiffness to reveal the mechanisms of force generation and transmission critical for MEK protrusion formation. Further, I will explore how protrusion mechanics affect cytoplasmic transport and partitioning of organelles required for functional platelets. Using super-resolution intravital imaging, I will investigate these processes in their physiological bone marrow niche. By integrating scRNAseq and live-cell microscopy, I will map morpho-dynamics with transcriptomics to identify the gene signature initiating protrusion formation of MEKs in response to mechanical stimuli. A novel MEK cell-system with optimized access to genetic manipulations will allow high-throughput screening of candidate genes.  Together, the unique combination of genetics, engineering, quantitative microscopy and intravital tools will pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Expansion of Media Content Use Cases: Exploiting Content-Technologies in Multimedia Products' (ExpaMeco) under Seventh Framework.

assistant: **Objectives**

The project ExpaMeco will transfer technologies, platforms, infrastructure and business perspectives of the ongoing FI-PPP ecosystem to the SME and web entrepreneur scene in the area of media. The take-up activities will address at least 25 new players, which will join the FI-PPP activities through three Open Calls. Each of the SMEs will be selected, supported, mentored and controlled by the partners of the consortium under the guidance of etventure which is responsible to manage the funds for the SMEs. etventure is a business development and venture company and will act as project agency, specialized to identify and accompany promising SMEs and web entrepreneurs. etventure is a driving force in the European start-up capital Berlin and provides extensive experience for launching and building start-ups in the online- and mobile sector. etventure will be supported by three companies (Thoughtbox, Weblify, F-Secure) to cover growing economies in Europe (Ireland/UK, Finland/Scandinavia, Poland/Eastern Europe). Additionally, Fraunhofer will bring in their extensive expertise in FI-PPP/content technologies and will connect the activities with the FI-PPP ecosystem. In particular, ExpaMeco has the following objectives:1) Strengthen the European web entrepreneur and SMEs in media, education and online services in order to shape its competitive position and growth2) Identify the most promising 25 web entrepreneurs and/or SMEs from at least 5 European countries through the execution of 3 European-wide, fully trans-parent Open Calls3) Leverage at least 15 Specific Enablers and 10 Generic Enablers in order to build innovative, scalable Minimum Viable Products for media-related market domains4) Ensure the large scale testing of the products developed by providing a mini-mum of 2.500 u
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Final state interactions in heavy flavour decays', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The precision study of complex multibody decays of bottom and charm hadrons has unique sensitivity to new fundamental particles and interactions that could give rise to the matter-antimatter asymmetry of the universe, or dark matter. New, vast datasets allow for these studies to be performed with unprecedented experimental precision. However, theoretical uncertainties limit the sensitivity of this approach. The proposed research overcomes this limitation by developing novel theoretical tools to describe multibody hadron decays, and applying them to the latest datasets in a unique collaboration between theory and experiment.In particularly, this research program focus on improving particles strong interaction description in the final states ofmultibody decays (B-->KKK, B--> Kππ, B-->K*μμ and Bc-->KKπ), including both low-energy two-body full amplitudes,with rescattering and coupled channels; and hight-energy charm mesons as intermediate states of the process.