RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Development and prevalidation of predictive models for catechol drug conjugation and their evaluation for rational drug design' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

- To establish relevant human recombinant enzyme expression systems for enzymes conjugating catechols to be used in drug metabolism studies- To develop and prevalidate models which predict the competitive conjugation of catechols for assessing safety and for the rational design of the catechol class of drugs.Metabolic interactions between catechol drugs and neurotransmitters and their competitive conjugation are highly relevant to new drug development, especially for the treatment of neurological and mental illnesses. Three reactions, glucuronidation, sulphation and O-methylation, compete for conjugation of catechol-derived compounds. Participants have expression systems for most cloned human isoforms of UDP-glucuronosyltransferase, sulphotransferase and catechol O-methyltransferase enzymes. Enzyme forms relevant for conjugation of catechols are identified and appropriate recombinant expression systems are selected. Enzyme assays which are suitable for determination kinetic constants for structurally diverse set of catechol substrates are developed, standardised and validated. Kinetic parameters will be determined for a set of catechols. The substrate set includes endogenous catechols, catechols drugs and other catechols selected to complement the set for optimal structural diversity. Computational chemistry and statistical modelling will be used to develop models, which predict the affinity of a given catechol to certain enzyme isoform and rate of conjugation catalysed by the respective enzyme form. The predictive ability of in vitro tests on individual enzymes and of empirical models based on their kinetic properties is evaluated by studying the conjugate profile produced by more complex systems like liver cells. Conjugates are quantitated and identified by means of c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'REDOX SIGNALING AND METABOLIC STATES IN ANGIOGENESIS IN HEALTH AND DISEASE' (2014-2020).

assistant: **Concept**

Endothelial cells (ECs) exhibit a remarkable and unique plasticity in terms of redox biology and metabolism. They can quickly adapt to oxygen, nitric oxide and metabolic variations. Therefore, EC must be equipped with a selective and unique repertoire of redox and metabolic mechanisms, that play a crucial role to preserve redox balance, and adjust metabolic conditions in both normal and pathological angiogenesis. The identification of such redox signaling and metabolic pathways is crucial to the gaining of better insights in endothelial biology and dysfunction. More importantly, these insights could be used to establish innovative therapeutic approaches for the treatment of those conditions where aberrant or excessive angiogenesis is the underlying cause of the disease itself. However, the formation, actions, key molecular interactions, and physiological and pathological relevance of redox signals in ECs remain unclear. Here, by using cutting-edge real-time redox imaging platforms, and innovative molecular and genetic approaches in different in vivo animal models, we will (1) reveal the working of redox signaling in EC in health and disease, (2) shed light on the novel role for the mevalonate metabolic pathway in angiogenesis and (3) provide solid evidence, that manipulation of endothelial redox and metabolic state by genetic alteration of the redox rheostat UBIAD1, is a valuable strategy by which to block pathological angiogenesis in vivo. The ultimate objective is to open the way for the development of innovative (cancer) therapeutic strategies and complement the existing ones based on genetic or pharmacological manipulation of redox rheostats to balance oxidative or reductive stress in angiogenic processes. The success of this project is built upon our major expertis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'The Degradation of Complex Modern Polymeric Objects in Heritage Collections: A System Dynamics Approach' in the context of a Horizon 2020 call.

assistant: **Objectives**

By viewing a scientific problem through the lens of heritage, COMPLEX will create an entirely new cross-disciplinary vision for understanding and modelling polymer degradation and build a world leading research team studying the degradation of modern polymeric objects in collections.  Rather than focussing on specific chemical or physical processes, as has been done in the past, COMPLEX will consider polymeric objects as almost akin to living organisms, and by using a system dynamics approach will model objects in their environments in a way that reflects their real complexity, with multiple, inter-connecting interactions between material properties and environmental parameters.As a polymer chemist, this project has been inspired by my 4 years of experience in the field of heritage, in particular by experiencing the problems raised by the conservation of modern polymeric objects such as plastics.  The development of modern polymers during the 19th and 20th centuries has changed history and society and they are a part of our material heritage that it is essential to conserve for future generations.  However, these objects are at risk due to their instability and a lack of knowledge within the museum sector as to their degradation behaviour.System dynamics models will be developed incorporating multiple chemical and physical interactions between the components of polymeric objects and environmental parameters such as relative humidity or light.  These will be used to predict the degradation behaviour of objects over time, to identify key parameters that are correlated to object change and provide practical solutions for heritage professionals.  Above all, COMPLEX will provide a new way of looking at polymer degradation, that can be applied across a wide range of fields, i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Integrity of repair welds in high temperature plant operating under steady and cyclic load conditions (INTEGRITY)' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The project is an effort to understand behavior and predict performance of repair welds in high temperature plants. A methodology for assessing high temperature components containing repair welds is being developed on the base of a scientific foundation for understanding and predicting creep/fatigue crack behavior in repair welded components and finite element models for relating microstructure and properties of the repair weld region to the behavior of components. Various situations of repair welds and four materials (ferritic, austenitic and martensitic steels) are being studied. Sophisticated FE modeling techniques encapsulating the complexities of repair welds and a number of lab and feature tests to validate FE models are used to produce an integrated remaining life assessment methodology and guidelines for the use of crack assessment procedures. This includes relations to NDT findings and consideration of residual stresses.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Conceptual approach for new routes in eHealth:Movement practices of elderly care' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Linked with the ‘demographic challenge’ of a rapidly aging population, there is an increasing move of healthcare practices into the home. At the same time ‘smart home’ technologies and other assistive devices are transforming homes into clinics. With these movements a range of new and alternative healthcare practices have emerged.The CareMoves project proposes to explore how formal and informal elderly care is reconstituted with an analytical focus on movement practices. The aim of the project is to understand what this focus might imply for new conceptualizations of healthcare and healthcare technologies. This will be done through the following three main research objectives:1.) Generate empirical knowledge of movement practices of elderly care in different healthcare settings, based on exploratory ethnographic research in the United States and Scandinavia;2.) Devise an alternative conceptual approach of elderly care formulated on this new empirical knowledge;3.) Enable knowledge transfer, exchange, and public dissemination with internal and external stakeholders.We anticipate that the CareMoves project will have immediate implications for new innovative routes in eHealth, mainly for assisting the lives of older people. Furthermore, we believe that the project will influence future public policies including the design of eHealth information and communication technologies (ICTs) for older people.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Rapid 90Sr determination using laser ablation ICP-QQQ-MS'.

assistant: **Concept**

As the Fukushima nuclear accident proved, the analytical laboratories cannot provide a rapid response for 90Sr contamination using the classic radiometric measurement methods resulting in poor public information which significantly decreases the trust towards governmental institutes. However, the monitoring of 90Sr is important since it is a “bone-seeker” element and is easily accumulated in bone tissues causing long term radiation exposure among the population. As a pure beta particle emitter radionuclide, the determination of 90Sr is a complex and time-consuming task (min. 1 day) due to the necessity of sample preparation and chemical separation of Sr.The scientific aim of this research project is to maximize the merit of mass spectrometry to fulfil the request of society for prompt and reliable information in case of a nuclear event. For this purpose, the latest state-of-the-art instruments, Agilent 8800 ICP-QQQ-MS and Cetac Teledyne Excite Excimer Laser ablation system will be used in an interdisciplinary approach to shorten the analysis time (<2 hours) and minimise the sample intake (<1 g). The new method will have a positive impact on environment protection because of the reduction of corrosive chemical usage. There will be further opportunities to determine radionuclides, such as U, Pu, I, and Cs isotopes giving benefit to the industrial application.To diversify the applicant’s competence and mend his shortcomings, training will be provided in student supervision, leadership, research funding and networking. The host and his institute will benefit from experiences related to the Fukushima accident, 90Sr analysis with mass spectrometry and explore new cooperation opportunities with Japanese and Hungarian researchers. With the help of this action, the applicant wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'New-generation bifacial solar tracker with integrated wind protection system for large scale photovoltaic arrays', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

With a turnover of €12 million, ESAsolar designs, develops, installs and operates large scale photovoltaic plants, focusing on panel structures and motorized solar trackers. We have completed over 40 successful projects in Europe and America, totaling over 500MW. The market for solar trackers is growing at a CAGR of 18.6% and will reach €25 billion by 2024. Solar trackers improve energy output by 25% over fixed structures. However, these structures also increase installation and maintenance costs, as well as structural risks. Wind damage is the main source of structural risk for trackers. It significantly shortens the lifespan of tracker arrays. Since PV plants need to resist over 20 years of service to be viable, the risk of systemic failures represents a considerable barrier for the growth of the tracker industry.Over the last years, we have been developing a line of solar trackers, with great commercial success. We have introduced advanced features, positioning ourselves as a technological reference. These features include self-powered motors, a computerized backtracking system, an innovative installation procedure and a bifacial system to catch both direct and reflected sunlight, thus improving efficiency by 5%. We will now upgrade our latest prototype with a unique system, called SecureTracker, that will stabilize trackers to avoid wind-induced structural damage. SecureTracker will provide an outstanding solution against structural risks in large scale arrays, extending average lifetime in 10 years. It will reduce overall Levelized Cost of Energy by 30% for utility-scale solar arrays. At a lower cost than alternatives, SecureTracker will give us a decisive competitive advantage, allowing us to increase yearly installations by 300% by 2026, resulting in over €25 mil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Stand-alone Photoelectrochemical Tandem Devices for Solar-driven Overall Water Splitting'.

assistant: **Innovation**

The project proposes to convert solar energy into hydrogen fuel by utilizing a thermoelectric integrated tandem photoelectrochemical (PEC) system with the main goal of generating a robust, scalable, and competitive solution of solar energy technologies. The project will focus on materials development, rigorous characterization, cell development, and prototyping. We will utilize solution-based techniques to address the urgent need for efficient absorbers for PEC systems via transferable methods for large scale production. We will target cost-effective and abundant materials for all required components without sacrificing their performance. Our proposed system will be the first work on solar driven-overall water splitting utilizing solution processing routes with benign molecular ink for photoabsorber synthesis coupled with earth-abundant and low-cost material cocatalysts. Furthermore, rigorous in-situ characterization will provide an overview of the overall processes involved in PEC reactions which will further guide system design. Finally, a prototype of an efficient and durable PEC cell will be realized.


**Keywords:** water splitting, tandem, PEC, kesterites, photovoltaics, photochemistry, photocatalysis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Harmonised Building Information Speedway for Energy-Efficient Renovation' under Horizon 2020.

assistant: **Concept**

‘BIM for renovation of existing residential building stock’ has been proven viable in innovative pilot projects by the members of BIM-SPEED consortium, among others in H2020 Smart Cities. The mission of BIM-SPEED is to take ‘BIM for renovation’ to a deep renovation level for at least 60% energy saving, and to accelerate the market uptake across the EU. In line with its mission, BIM-SPEED aims to enable all stakeholders to adopt BIM to reduce the time of deep renovation projects by at least 30% by providing them with: 1) an affordable BIM cloud platform, 2) a set of inter-operable BIM tools, and 3) standardised procedures for As-Built data acquisition, modelling, simulation, implementation and maintenance of renovation solutions. BIM-SPEED relies on a trans-disciplinary approach comprising (i) process, (ii) ICT, and (iii) social innovation with a special attention to the stakeholders as a key success factor for BIM adoption. The interoperability of a full range of BIM tools for renovation will be accommodated on an innovative BIM cloud platform, which will be launched and available free-of-charge for all stakeholders immediately from the beginning of the BIM-SPEED project. BIM-SPEED will engineer the seamless integration and quick installation of building and HVAC products for renovation into the existing buildings. Such Plug-and-Play solutions are crucial for the overall time reduction. BIM-SPEED consortium represents all players in the renovation market. Throughout a 4-year project duration, BIM-SPEED will demonstrate the holistic solution in 12 real demonstration cases. An EU-wide BIM Competition will be jointly organised by the European umbrella organisations in all disciplines (architects, HVAC engineers and construction firms) to kick-off the first market replicati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'What to do With the Wi-Fi Wild West' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The last few years have witnessed a significant increase in the use of portable devices, especially smartphones and tablets thanks to their functionality, user-friendly interface, and affordable price. Most of these devices use Wi-Fi Access Points (AP) where possible, in addition to 3G/4G, to connect to the Internet due to its speed, maturity and efficiency. Given this demand, Wi-Fi is facing mounting issues of spectrum efficiency due to its utilisation of non-licensed frequency bands, so improvements continue to be added to standards in order to improve performance and adapt it to new demands. For example, as Wi-Fi saturation increases in areas, such as business centres, malls, campuses or even whole European cities, interference between these competing APs can begin to negatively impact users’ experience. At the same time, real-time interactive services have grown in popularity and are now used across a range of mobile devices. These share the same connection with “traditional” applications, such as e-mail and Web browsing, but are far more bandwidth intensive and require consistent network capacity to meet user Quality of Experience demands. In this context, Wi-5 Project (What to do With the Wi-Fi Wild West) proposes an architecture based on an integrated and coordinated set of smart solutions able to efficiently reduce interference between neighbouring APs and provide optimised connectivity for new and emerging services. Cooperating mechanisms will be integrated into Wi-Fi equipment at different layers of the protocol stack with the aim of meeting a demanding set of goals:• Support seamless hand-over to improve user experience with real-time interactive services• Develop new business models to optimise available Wi-Fi spectrum in urban areas, public spaces, and offi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Reinvented through Crises: The Political Economy of the Western European Left within European Integration' (CrisEU) targeting Horizon Europe.

assistant: **Abstract**

Due to recurring economic and political shocks, the past decade has consolidated crisis-management and resilience as a key priority of the European Union (EU).  Academic research has long interrogated the ways in which crises are dealt with at the European level. Yet, the excessive emphasis on electoral trends or elite-led processes has failed to capture the long-term quiet politics  of support towards European integration. The role of European progressives, a key source for the European ideals of solidarity and internationalism, has received little attention. This is surprising given the fact that progressive politics  and European integration  have both experienced a long series of mutations and adaptations shaped by recurring crises. While these processes have been studied separately, little attention has been given to their intersection. As a result, progressive politics has been conceptualised as a passive victim of increasing integration  and the EU is often seen as squeezed in the middle between populism and technocratic decision making. CrisEU will build a theoretically informed and impact-oriented study to investigate the ideas and group characteristics that through critical junctures create long-lasting support to integration. The main hypothesis I will investigate is that progressive politics is ‘reinvented’ at different stages in relation to three interrelated factors: 1) The changes in the composition of left-wing social networks (in relation to gender, age, education, etc.); 2) The evolving memories of past crises; 3) The shifting understanding of what is needed to ensure Euorpean integration. Beyond academia, the proposed research will help political parties and trade unions identify the factors that drive (dis)integration within the EU, the ways in which