RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Read the fine print: Zooming into paleoenvironmental and biogeochemical processes through molecular imaging of biomarker distributions in sediments' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Lipid biomarkers provide unique information to disciplines such as paleoceanography, paleoecology and biogeochemistry. Factors limiting their scope include high sample demand and analytical complexity, constraining resolution of time and space to decadal and centimeter scales, respectively. However, dynamic interactions between physical, chemical and biological processes are recorded within sedimentary matrices at finer scales; lipid biomarkers could decode this sedimentary fine print if the limitations of resolution could be overcome. In a recent PNAS paper, we have demonstrated that this can be done and shown that µm-scale molecular images of paleoenvironmental and geobiological processes can be obtained directly on surfaces of cut sediment cores via laser desorption ionization coupled to mass spectrometry. The project ZOOMecular will build on this innovation by interrogating laminated sediment archives of Late Quaternary climate change and dissecting the complex environmental and ecological responses at subannual resolution. Through analysis of spatial associations of lipid biomarkers with the sedimentary matrix, we will provide a new view of the mechanisms underlying delivery to and preservation of molecular signals in sedimentary records. ZOOMecular will seek to examine the microbial habitat niches at sedimentary interfaces that are home to globally important biogeochemical processes but that are largely known from studies of cm3-scale samples. To enable these pioneering studies, we will develop innovative analytical protocols for a suite of informative biomarkers and for the acquisition of congruent molecular and elemental maps of geological samples. ZOOMecular will unlock otherwise inaccessible information of broad geoscientific relevance; its goals go far beyond
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Active and Passive MIcrowaves for Security and Subsurface imaging' under Seventh Framework.

assistant: **Concept**

AMISS proposal aims at establishing a collaborative network that will be able to acquire international visibility by providing theoretical and applicative advancements in the field of the active and passive microwave imaging systems. The proposal involves three EU Members  and Associate Countries (Italy, The Netherlands, Turkey) and 4 partners from Third countries (Russia, Ukraine, Brazil) whose expertise is complementary in achieving the objective of the proposal and in ensuring a significant transfer of knowledge.Two main lines of activities will be developed during the project.The first line of research is concerned with the development, characterization and performance evaluation of new systems, sensors and configurations able to mitigate the clutter, and increase information content and redundancy, for both passive and active microwave imaging.The second line of research is concerned with the development, implementation and performance evaluation of processing tools. State-of-the-Art processing tools will be adapted to the novel instrumentation developed in the first line and to work in electromagnetically complex scenarios encountered in emerging application domains.The effectiveness of the research and exchange activities, and of the related results will be tested by considering two specific application fields. The first one is concerned with the Ground Penetrating Radar for subsurface sensing and critical infrastructure diagnostics,while the other one regards passive and active microwave imaging systems for security applications.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Higher-Order Rewriting for Intensional Properties of Programs and Circuits' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The HORIP project will employ higher-order term rewriting to characterise intensional program properties: properties concerned with ""how"" rather than ""what"" a program computes, such as complexity, compressibility and safety.Term rewriting is a formal system which can be used to specify algorithms. Unlike common programming languages, term rewriting has a simple, formal definition which admits non-determinism. Higher-order term rewriting is an extension therof, which shares these advantages but has greater expressivity.To analyse program properties, we may either use dedicated techniques, or translate queries into different fields, with term rewriting as a powerful option. In doing so, methods from widely different areas can be applied.HORIP aims to analyse intensional properties using higher-order term rewriting. The first phase will attack two lines of research ripe for success: implicit complexity and compiler correctness. For the former, the supervisor is an expert in complexity and the fellow in higher-order term rewriting. For the latter, we will work together with industry collaborator Dr. Rose, who develops the CRSX framework which seeks to describe compilers using a special form of higher-order term rewriting. Leveraging the expertise of all three parties and potential local collaborators, strong results are expected, especially since the higher-order setting avoids many intrinsic limitations of previous work. In the second phase, we extend these ideas to complexity and compressibility of logical circuits. This builds on the first year's experience with implicit complexity, and the expertise of the scientist-in-charge.HORIP is basic research, building on very recent advances from several international research groups. There are potential future business appl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Electronic and Ionic Transport in Functional Oxides' under Seventh Framework.

assistant: **Concept**

Two of the main drivers of worldwide economic growth and scientific development are the semiconductor/IC industry and the need for new energy resources. The need for alternate renewable sources of energy such as sunlight and wind power which are inherently discontinuous, poses new challenges for energy transport and storage. Although many of the materials used in the IC industry and in energy storage are similar, the research in their properties has been separated in two fields with very little interdisciplinary interaction. This proposal aims to cross this barrier and evaluate physical and electrical properties of transition metal oxides in their nanostructured form for non-volatile memory and energy storage applications. For this we will investigate how material production and physical properties influence electronic and ionic transport properties in these oxides. We propose to evaluate transition metal oxides, starting with simple binary oxides such as vanadium oxides and assess how material production and physical properties influence electrical and/or ionic transport properties. A first objective is to identify materials where resistive switching can be ascribed to correlated electron effects rather than oxygen or oxygen vacancy rearrangement. It is interesting to determine how these effects are influenced by size and confinement. This is done keeping in mind possible applications as switch/ memory elements. Some oxides are expected to show relatively high ionic mobility making them good candidates for alternate battery materials. For this, screening of ionic mobility of the intrinsic oxide and of Li in the oxide is to be investigated. Correlating oxygen mobility in the lattice with Li mobility can help better engineer materials for highly performing batteries.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Imaging device for electrophysiological activity monitoring of neuronal cell cultures' (IDEA).

assistant: **Innovation**

Extra-cellular recordings from excitable cell cultures using microelectrode arrays (MEAs) are now a well-accepted technique in both fundamental neuroscience research and applied electrophysiology. Nevertheless the current technological limitations restrict the mapping of spatio-temporal patterns capabilities of MEAs. In order to gain access to more detailed information on distributed processing, synaptic plasticity and spatially propagating activity patterns, the capabilities of recording the electrophysiological activity of increasingly complex electrogenic cell networks (i.e the MEAs mapping features) have to be upgraded. This requires the development of new high-resolution experimental tools. The aim of this project is to develop an enabling technology platform, based on an Active Pixel Sensor (APS) concept and signal and data processing algorithms for high spatial and temporal resolution recording and analysis of the electrophysiological activity of neuronal networks. The APS technology is used in CMOS cameras for example for fluorescence measurements. Our approach is based on changing the light-sensitivity pixel functionality to create a high-density array of metallic microelectrodes on a large active surface area. The APS-MEAs technology allows the integration of in-pixel and on-chip electronic circuits for signal amplification and high-speed addressing. The proposed technological platform together with the appropriate development of advanced signal and data processing algorithms will provide the scientific community a new validated experimental tool allowing to correlate local and intrinsic features at single cell and small neuronal network levels with global dynamic features of large assemblies of neurons.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The development of a UV/ozone surface cleaning technology for high quality adhesion applications' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

Reliable and sustainable adhesive bonding, coating or soldering for instance. in the assembly of optical. electrical and computer components primarily depends on the achievement of an ultimale clean surface. UV/ozone cleaning is capable in removing the final atomic layers of organic surface contaminants. The combination of UV-light and ozone decompose organic molecules into carbon dioxide and water. The UV-ozone technique is an easily accessible, fast, reliable, safe and ecologically sound cleaning method for ultimate surrace treatment, and an alternative for many acid/base and organic solvent based cleaning methods (CFCs, hydrocarbons, etc.). The objective of the project is to optimize the UV/ozone surface cleaning technique.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Animal Models of Human Diseases: Practical Issues' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

In recent years, animal models have become crucial to the development of basic and therapy-oriented biomedical research and tremendous methodological and technological progress has been achieved in the field of the genetic engineering and phenotypic analyses of animal models of human pathologies.Transgenic animals offer new opportunities to analyse the physiopathological consequences of defined molecular lesions, notably important to a better understanding of cancer, and of immune-mediated and age-related diseases, and to devise new therapeutic strategies. These animals constitute a new biological resource which should shed light on the basic mechanisms governing these diseases of considerable and rapidly growing socio-economic importance to European society.There exists a strong, transdisciplinary need and a similar demand, in the academic and industrial settings, for scientists trained in the principles and practice of phenotypical analysis of animal models.The present proposal for a series of 3 annual Eurolab Courses on animal models of human diseases will respectively address the practical issues related to animal models for research on cancer, on immune-mediated diseases and on age-related diseases. They will focus on new, cutting-edge techniques for the engineering of animal models and on the methods used to harvest and interpret the data they allow to collect.This proposal for a series of 3 Eurolabs is presented in tandem with an application for 3 annual Euroconferences which will address the scientific, ethical and legal issues related to research with animal models as applied to cancer, immune-mediated diseases and age-related diseases.ftp://ftp.cordis.lu/pub/improving/docs/HPCF-2000-00394-1.pdf
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Exploring Anti-GentrificAtion PracticEs and policies in Southern European Cities', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The overall aim of AGAPE is to explore and improve our knowledge of anti-gentrification practices as performed in the urban space of Southern European cities (SECs), specifically Rome, Madrid and Athens, with a particular focus on their incorporation into - and capabilities to inform - local policy makings. In SECs the effects of gentrification are now being exacerbated by the debt crisis and the consequential austerity behaviors of nation states. For this reason, SECs offer an opportune setting in which to study the relationship between gentrification and policy, as well as forms of resistance and alternative responses to gentrification. Empirical evidence suggests that there are emerging practices of reaction, and alternative solutions, to the hegemonic narrative of the “commodified city” in SECs that are directly addressing the broader issue of the habitability of the city. However, these practices appear to be fragmented and we lack systematic understanding of their potential and their capabilities in countering urban inequalities. As such anti-gentrification practices and policies performed in these three SECs will be investigated and compared in order to construct a model of territorial capacities: capacities to counter the hegemony of gentrification at this particular ‘political’ moment in time, by incorporating far sighted and socially just policies for the re-use of the material assets of these cities. Such an exploration will provide much needed theoretical and empirical material for a post-crisis urban agenda aimed at  achieving social justice and equity. The findings of the research will inform an academic narrative of resistance that will highlight ‘alternative narratives’ based on counter-gentrification practices in these three cities. The research finding
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Plug&plAy eneRgy ManagEmeNt for hybrID Energy Storage'.

assistant: **Innovation**

The ongoing transition of the energy system is accompanied by digitalization activities, enabling new applica-tions. This results in a fragmentation of existing platforms, protocols, and standards. Therefore, interoperability among various platforms as well as cross-domain interoperability must be ensured. The usage of ontologies provides an opportunity to address cross-platform and cross-domain interoperability. PARMENIDES aims to develop a new ontology by extending existing ontologies to provide a knowledge base, with a focus on the elec-tricity and heating domain for buildings, customers, and energy communities. It will support different use cases, focusing on the utilization of Hybrid Energy Storage Systems (HESS). Besides the representation of storage technologies, information about energy community customers, their behaviours, and components including their relation will be part of the ontology, providing a standardized vocabulary of the domain of energy communities. This further includes technical, economic, regulatory, behavioural, and social constraints to be considered in operation. To support a number of use cases, a new generation of innovative Energy Management Systems (EMS) will be developed. This system will be capable of using ontology as a knowledge base. This will enable a very generic software design and ensures the scalability and replicability of the solution. As a framework for the integration of the EMS, PARMENIDES will define an information and communication architecture, enabling an interoperable, reliable, and secure exchange of data and instructions. The developed EMS will be demonstrated in very diverse pilots in Austria and Sweden. The Austrian pilot will address energy communities with different storage technologies, the Swedish pilot will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'DAta and Voice Integration over DWDM' (DAVID) under Fifth Framework.

assistant: **Objectives**

Main objective is to propose a Packet-over-WDM network solution, including traffic properties and management, based on optical packets and asynchronous transmission over metro and backbone distances. The project will capitalise on both optics and electronics to find out the optimum combination to reach multi-Tb/s capacity. To cope with the on-going convergence in the transport of voice, data and multimedia applications, the project will also define several classes of service, adapted to optical layer specifics. On the metro side, the project will consider a buffer-less network using a medium access control protocol. The backbone will be based on 10 Tb/s multi-layer (wavelength and packet) opto-electronic medium access control protocol with opto-electronic packet routers, incorporating core and edge functions. Finally, the project will demonstrate highly integrated optical and electronic devices, included in a sub-equipped experimental platform.Work description:A first task will be to tackle the network issues:- Define network requirements and functional specifications of the network elements;- identify a migration path from short-term approaches;- Carry out traffic studies to analyse IP traffic behaviour when transported over WDM, and propose optimised buffering schemes, access control protocols and routing algorithms taking into account a multi-QoS environment;- Investigate network management issues, such as interoperability between packet and WDM levels.A second task will be to investigate and implement the required network elements:- A network testbed will be implemented with its associated access control protocol to show a buffer-less multi-QoS optical packet metro network of capacity beyond 1Tb/s (2.5Gb/s line-rate);- A 10-Tb/s opto-electronic optical packet router
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Novel Metabolic Pathways in Cancer'.

assistant: **Concept**

Metabolic adaptations in central carbon metabolism play a key role in cancer. Yet, the success of therapeutic interventions in major pathways has been limited, although some of the changes have been known to exist for almost 100 years. Biochemical textbooks present intermediary metabolism as something canonical, and the molecular identity of most enzymes required for the production of known intermediary metabolites is indeed known. Yet, the function of many putative enzymes is still unknown, indicating that novel metabolic pathways containing so far unknown metabolites exist. We have recently discovered a novel metabolic pathway containing two metabolites that have never been described before. Preliminary data indicate that this pathway might play an important role in a group of cancers sharing specific mutations. Furthermore, genetic inactivation of a component of this pathway in mice is compatible with normal development, indicating that pharmacological inhibition should be well tolerated.In the present project, we will use a multi-dimensional approach combining biochemical, genetic and pharmacological techniques, to identify missing components of this metabolic pathway and assess its role in cellular metabolism and cancer development. In the process of this, we will develop tools that will allow us to test whether this pathway can be targeted in vivo. Thus, our work will lead to the description of a novel metabolic pathway, should reveal novel regulatory circuits and might open novel therapeutic avenues in cancer and beyond.


**Keywords:** cancer metabolism