RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Energy-efficient Heterogeneous COmputing at exaSCALE' under Horizon 2020.

assistant: **Concept**

In order to reach exascale performance current HPC servers need to be improved. Simple scaling is not a feasible solution due to the increasing utility costs and power consumption limitations. Apart from improvements in implementation technology, what is needed is to refine the HPC application development as well as the  architecture of the future HPC systems.ECOSCALE tackles this challenge by proposing a scalable programming environment and hardware architecture tailored to the characteristics and trends of current and future HPC applications, reducing significantly the data traffic as well as the energy consumption and delays. We first propose a novel heterogeneous energy-efficient hierarchical architecture and a hybrid MPI+OpenCL programming environment and runtime system. The proposed architecture, programming model and runtime system follows a hierarchical approach where the system is partitioned into multiple autonomous Workers (i.e. compute nodes). Workers are interconnected in a tree-like structure in order to form larger Partitioned  Global Address Space (PGAS) partitions, which are further hierarchically interconnected via an MPI protocol. Secondly, to further increase the energy efficiency of the system as well as its resilience, the Workers will employ reconfigurable accelerators that can perform coherent memory accesses in the virtual address space utilizing an IOMMU. The ECOSCALE architecture will support shared partitioned reconfigurable resources accessed by any Worker in a PGAS partition, and, more importantly, automated hardware synthesis of these resources from an OpenCL-based programming model.We follow a co-design approach that spans a scalable HPC hardware platform, a middleware layer, a programming and a runtime environment as well as a high-level
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The Euro-African Migration, Development, Security Nexus in West Africa: Negotiating Mobility in Mali and Burkina Faso' to be submitted under Horizon 2020.

assistant: **Abstract**

For about a decade, the EU experiments what it perceives as an unprecedented “migration crisis”. Moreover, since the mid-2000, the US-European agenda has integrated West Africa into the ‘Global War on Terror’ and uses its development cooperation to promote its policy. This migration-development-security nexus became a major political problem, prompting discourses, policies and dispositifs of crisis impacting African mobility. Based on a qualitative, empirical and comprehensive perspective, NEGOMOBI will investigate this nexus via the Malian and the Burkinabe case studies, in a comparative perspective. NEGOMOBI has 3 main objectives. The first one is to conduct a retrospective of the career of this Euro-African nexus as a public problem, through the design of both case studies. This will involve a work of historicization of migration and security policies promoted by Western countries in Mali and Burkina in a postcolonial setting. The second one is to study the actual policy-making process promoting this nexus and the negotiations between the EU and Mali and Burkina Faso on cooperation agreements as an attempt to solve this migration-security crisis. Finally, based on an ethnography of bus stations in Bamako and Ouagadougou, the third objective is to describe the implementation ‘from below’ of this nexus, its effects and counter-effects on West-African mobility, and the tactics and strategies developed by local actors, with a specific focus on gender issues on one hand, and on materiality on the other hand. It examines how border management and controls through technical and technological infrastructure are shaping human experience, masculinity and femininity, mobility and security in bus stations. By following the chains of actors, NEGOMOBI investigates how scales are c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'APPLICATION OF PHEROMONES AND OTHER SEMIOCHEMICALS FOR PEST CONTROL IN MAIZE' (PHEROMAIZE).

assistant: **Innovation**

This proposal brings together two private firms from two European countries and six RD&T public institutions from four European countries. All of them have a great deal of experience working an pheromones and MCB and in the last few years they have obtained significant results in the research and application of heromones for the control of MCB and other pests (see patents and publications in partnership description). The composition of the research teams (industrial and laboratory chemists, insect ecologists and physiologists, basic and applied researchers, extensionists, field workers) guarantee a multidisciplinary and realistic approach and the practical application of the results.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Fate, activity and threat of ralstonia solanacearum, the causal agent of potato brownrot, in european soils,rhizospheres and water systems' (FATE) targeting Fourth Framework.

assistant: **Abstract**

Potato brownrot, the disease caused by Ralstonia solanacearum, is a serious emerging problem in European agriculture, with severe losses recorded in recent years in potato cropping. Several recent reports have indicated that the causal agent, R. solanacearum race 3, may have established in European soil, plant and water systems in various countries of the Union. This proposal by 5 European expert laboratories aims to assess the severity of infestation by the pathogen, as well as the effects of simple non-chemical practical methods taken against it. The project will first fine-tune available methods for the detection, identification and ecological monitoring of the brownrot bacterium. Partners will subsequently perform a European transect study aimed at investigating the prevalence as well as load of R. solanacearum in several European ecosystems. This study will provide information as to pathogen incidence, as well as generate strains which will serve as target organisms for subsequent ecological assessments of fate and persistence. Such strains will also be characterized for their aggressiveness versus a broad selection of potential host plants. In a third phase, the experiments will focus on the fate of R. solanacearum strains selected in the transect study, following a release from diseased potato tubers in soil, its fate should it enter waterways and the potential for a diversity of plants to serve as reservoirs of the bacterium. The capability of the bacterium to enter a viable-nonculturable state, which would escape current certified detection methods will be assessed. Furthermore, the response of R. solanacearum to stressful conditions encountered in soil and water systems, potentially leading to a multiply-stress resistant physiological state, will be determined
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Symplectic Measurements and Hamiltonian Dynamics' (SYMPLECTIC) targeting Horizon 2020.

assistant: **Abstract**

Symplectic geometry combines a broad spectrum of interrelated disciplines lying in the mainstream of modern mathematics. The past two decades have given rise to several exciting developments in this field, which introduced new mathematical tools and opened challenging new questions. Nowadays symplectic geometry reaches out to an amazingly wide range of areas, such as differential and algebraic geometry, complex analysis, dynamical systems, as well as quantum mechanics, and string theory. Moreover, symplectic geometry serves as a basis for Hamiltonian dynamics, a discipline providing efficient tools for modeling a variety of physical and technological processes, such as orbital motion of satellites (telecommunication and GPS navigation), and propagation of light in optical fibers (with significant applications to medicine).The proposed research is composed of several innovative studies in the frontier of symplectic geometry and Hamiltonian dynamics, which are of highly significant interest in both fields. These studies have strong interactions on a variety of topics that lie at the heart of contemporary symplectic geometry, such as symplectic embedding questions, the geometry of Hofer’s metric, Lagrangianintersection problems, and the theory of symplectic capacities. My research objectives are twofold. First, to solve the open research questions described below, which I consider to be pivotal in the field. Some of these questions have already been studied intensively, and progress toward solving them would be of considerable significance. Second, some of the studies in this proposal are interdisciplinary by nature, and use symplectic tools in order to address major open questions in other fields, such as the famous Mahler conjecture in convex geometry. My goal is to deep
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Optimisation of a non-antibody based technology to improve the efficiency of genome-wide analysis of DNA binding sites' (2002-2006).

assistant: **Innovation**

Development of genome wide tools to study regulatory elements is particularly important to understand how gene expression is controlled in the human genome. The rational study of transcription factors and DNA-binding proteins in sequenced human genome is critical for making the genome sequences maximally useful.Chromatin Immuno-Precipitation (ChIP) materials analysed on microarrays for specific interactions (ChIP-chip) is a rapidly emerging technology in the study of DNA binding regulation proteins. A major current limitation of this technology is the lack of high quality antibodies proven to work.Therefore, the use of an appropriate approach to produce high specific functional binding agents for high throughput functional genomic studies by ChIP-chip is crucial. The present proposal implements an approach for single-step purification of transcription factor and DNA-binding protein complexes based on specific in vivo biotinylation.For this purpose the humanized (codon optimized) bacterial BirA biotin ligase and the target proteins of interest tagged with a biotin acceptor domain of 13 amino acid residue will be co-expressed in mammalian cells. This will provide the high-specific immuno-precipitation of in vivo biotinylated proteins with their DNA binding sites by strong biotinstreptavidin interaction.This approach can be scaled up and can serve as the basis for successful genome wide studies. Through the use of this powerful assay important biological questions will find response. By accelerating the ChIP-c hip studies, this approach will help to better understand the gene regulation.By identifying the DNA sequences reacting with regulatory proteins this approach will help to make the genome sequences maximally useful for further studies and classification, which will a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Intelligent Portable Border Control System' under Horizon 2020.

assistant: **Concept**

iCROSS envisages to enable faster thorough border control for third country nationals crossing the borders of EU, with technologies that adopt the future development of the Schengen Border Management. The project will present an optimal mixture of an enhanced, voluntary form of a Registered Traveller Programme and an auxiliary solution for the Entry/Exit System based on involving bona fide travellers. iCROSS designs and implements a system that adopts mobility concepts and consists of a two-stage procedure, designed to reduce cost/time spent per traveller at the crossing station. It leverages software and hardware technologies ranging from portable readers/scanners, various emerging and novel subsystems for automatic controls, wireless networking for mobile controls, and secure backend storage and processing. The two-stage procedure includes: (A) the registration before the travel to gather initial personal, travel document and vehicle data, perform a short, automated, non-invasive interview with an avatar, subject to lie detection and link the traveller to any pre-existing authority data. Utilizing multifactor analytics and risk-based approach, the data registered is processed and correlated with publicly open data or external systems such as the SIS II. Processing will need the travellers consent as set in EU legislation and national law. (B) the actual control at the border that complements pre-registered information with results of security controls that are performed with a portable, wireless connected iCROSS unit that can be used inside buses/trains or any point. Multiple technologies check validity and authenticity of parameters (e.g. travel documents, visa, face recognition of traveller using passport picture, real-time automated non-invasive lie detection in in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Functional roles of astroglial connexins in the generation of sharp wave ripples' under Seventh Framework.

assistant: **Concept**

It is believed that sleep plays an important role in memory consolidation. In rodents, hippocampal neurons (place cells) selectively discharge when the animal is in a specific location in space. During subsequent sleep, they are reactivated in the same order at 200Hz network oscillations known as ripples. This timescale is optimal for synaptic plasticity underlying memory. The host team (Rouach) has recently shown that connexin 30 (Cx30), a main gap-junction subunit in astrocytes, regulates excitatory synaptic transmission and is upregulated in mice raised in enriched environments known to enhance learning and memory. In addition, the lack of Cx30 impairs behaviour and responsiveness to novelty implying an important role for Cx30 in behavioral, cognitive processes, and physiological network activity. However, the mechanisms involved in this role are still unclear since Cx functions extend beyond intercellular communication and include hemichannel-mediated and channel-independent functions. This project aims to investigate the role of astroglial Cx30 in ripples activity and the physiological and molecular mechanisms involved. The researcher (Cheung) has ~8 years of experience and success in research on both neurons and glia from labs in Germany and UK. After a career break, she is determined to resume her research career by leading this project in France at the host team, which is internationally recognised in the field of neuroglial and Cx physiology. In collaboration with a team of experts in electrophysiology in freely behaving animals (Zugaro), a unique multidisciplinary approach combining in vivo and in vitro electrophysiology, pharmacology and molecular biology will be taken. The Marie Curie Intra-European Fellowships for Career Development will provide an ideal pl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Deciphering sex differences in the human immune system'.

assistant: **Objectives**

Women face a four-fold higher risk of developing an autoimmune disease compared to men. Sex differences in immune-mediated disorders are well-documented, but have remained poorly understood and are not taken into account in current therapies. To improve treatment of sex-biased autoimmune disorders I believe it will be essential to gain a much deeper understanding of fundamental factors controlling sex differences in the human immune system. The present proposal applies two uniquely informative human model systems to determine the separate roles of sex hormones and sex chromosomes in immune regulation. First we will investigate how the immune system is transformed during female-to-male and male-to-female sex change, utilizing samples collected in a multicenter study that I am coordinating. A combination of broad-scale technologies will be applied to follow dynamics provoked by sex hormone transition in peripheral blood immune cells, autoimmune reactivity, plasma proteins, and gut microbiota. As a complementary model to capture effects mediated by sex chromosomes, we will study mosaic individuals harboring immune cells with both female and male karyotypes in peripheral blood. Single cell transcriptomic analysis will be used to compare these cell populations, thereby revealing the influence of chromosomal sex in an otherwise fixed genetic and hormonal background. These model systems will be combined with population-based studies - taking advantage of new data on sex hormone levels and sex chromosome karyotypes in 500,000 women and men (UK Biobank), which will allow us to determine how these factors ultimately influence the risk of autoimmune disease.  I believe this novel approach will offer groundbreaking insights into the biology of sex differences of human immune system
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Innovative Fault-free Wood Wool Cement Board from Superior Wood Wool Produced by Operator-friendly, Environmentally Friendly and Cost Saving Methods' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Boards of various width and thickness can be produced using the wood wool from the new rotating wood wool shredding machine which gives excellent results. Boards for acoustic ceilings with wood wool of 0.75mm wide can be attained with the complete omission of any chip or irregularity in the wood wool due to the slightly sidewise curved strands. These strands make it extremely unlikely that two strands line up parallel to each other as occasionally happens with straight strands. The development of the rotating wood wool machine has brought about more advantages than just the savings of labour as originally aimed for. It is well known in the industry that the job of wood wool shredding is dangerous and dust and noise may harm the operator's health. As the rotating wood wool shredding machine operates fully automatically, no operators are needed, thus solving the problems concerning the operators health and dangerous working conditions. In some countries in Europe, for reasons of safety, the traditional wood wool machines are not allowed to be serviced by hand while running and are now fully encaged. The machines have to be stopped before wood can be added, turned or removed, and can only be started again when the doors of the cage have been closed. With the rotating wood wool shredding machine several interesting developments have been realized such as a quick snap-lock system for changing the knives in the disc, a continuously variable disc rotation speed and two shredding positions with each an advanced system to firmly hold the feed and wood blocks down to the disc. The main properties of the rotating wood wool shredding machine are: completely safe working environment; due to the high capacity the machine, it replaces 8 to 10 traditional machines giving significant sa