RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Macrocycles for Drug Discovery'.

assistant: **Objectives**

Better drugs are one of the most efficient and sustainable ways to improve health care, a key strategic orientation in Horizon Europe.New drug modalities such as macrocycles are expected to be a key enabling technology for this strategic perspective. The goal of MC4DD is to train the next generation of European medicinal chemists in a multidisciplinary environment to promote European drug discovery competitiveness, directly by advancing knowhow on macrocycles and long-term via the skills carried on by the researchers trained in the doctoral network.


**Keywords:** Pharmacology, drug modalities, drug discovery and design
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Joint affordance perception' (JAP), addressing dissemination and exploitation.

assistant: **Impact**

When acting on the environment with another, it is critical that we understand the actions made possible by not only the properties of the environment, but by the capacity of the dyad. How we perceive these action possibilities, or affordances, for the dyad is a fundamental question in understanding joint action. The proposed project, JAP, aims to provide one of the first systematic and interdisciplinary – combining behavioural and neurophysiological data – investigations into the conditions under which affordances for the dyad (or joint affordances) are perceived, as well as the processes that underpin them. The present project will use object-based stimulus-response compatibility paradigms, which produce response time and error data that can be used to measure affordance-elicited motor activation. Additionally, eye-tracking and electroencephalogram (EEG) data will be collected during these tasks to answer questions about the processes by which joint affordances are perceived. This data will be used to study: (1) the role of attention in joint affordances, (2) how perceiving others’ actions informs one’s own affordance perception, and (3) how social bonds modulate affordance perception. Results from the proposed studies will provide novel insight into how we can rapidly and efficiently form joint action plans that account for action-relevant properties of the dyad and environment.


**Keywords:** joint action, affordances, object-based compatibility
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Fabrication of microlenses and microreaction vessels from polymers' (1998-2002), addressing dissemination and exploitation.

assistant: **Impact**

A novel method for the fabrication of micro reaction vessels and micro lenses will be explored. In this method a droplet of solvent (diameter between 50 and 500 µm) is sprayed onto a flat polymer substrate. After evaporation of the solvent a lenticular cavity is formed. This can also be employed as a template for a lens.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Integrated formal approaches for embedded real-time systems', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The objective of the INFORMA project is to satisfy the urgent needs of integrating currently used standard technologies among them and with formal methods within a common framework. In the resulting environment, current standard methods and tools will cooperate with each other and benefit from the use of formal methods to improve the whole development cycle and increase the quality of the final product. In this way, it will be possible to reduce development costs as well as to increase the reliability of the final product.Standard techniques will be fully integrated in a common framework and enhanced with animation and analysis capabilities. Animation, and analysis of ISO-PLC models will be based on a formal model, namely high-level timed Petri nets (HLTPNs) and HLTPNs will be derived automatically from ISO-PLC specifications. Integration with the specifications of the analogue embedding given by Matlab/Simulink will be provided by interfacing the kernel formal model with Matlab/Simulink externals". VDM++ will be suitably connected to ISO-PLC by means of the HLTPN kernel model. C++ and C code will be automatically generated from both VDM++ and the HLTPNs derived from ISO-PLC. The VDM++ tool-set will be based on technology developed within the AFRODITE project. Technology from the IDERS project will be used to provide animation and verification capabilities based on the HLTPN formal kernel. Model checking technology will be applied to HLTPNs for formal proof of critical time-dependent properties.The environments will be validated on two industrial applications:- Ansaldo Industria will validate the INFORMA technology on an electrical drive controller that regulate the motor speed by injecting with high precision the current in motor coils through an electronic converter.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Research, development and evaluation of environmentally friendly in-mould coatings for thermo-composites'.

assistant: **Innovation**

European legislation related to styrene emissions is having far reaching effects in the fibre-reinforced plastics (FRP) industry. This has driven the development of zero emission, environmentally friendly Thermo-composites, a combination of polypropylene and glass fibre, as a replacement for traditional resin based materials. A limitation to market acceptance of these materials has become apparent in the lack of a suitable zero emission in-mould surface finish, an equivalent to the gel coat. It is in the coating process that peak emissions occur and therefore styrene emissions still exist in the process. The overall objective of this project is to develop and evaluate a completely new solvent free in-mould coating addressing areas of application, bonding, long term environmental performance, surface finish and potential for recycling. This coating will have a thermo setting application but behave in a Thermo plastic way and will compliment the development of Thermo-composites to assist in a broader market acceptance of the material.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Synthesis of Liquid-filled Micro-particles as Icy Cosmic Dust Analogues' (SLIMPICODA), addressing dissemination and exploitation.

assistant: **Impact**

Shock processes involving volatile-bearing bodies are of extreme interest in planetary science and astrobiology, due to the role volatiles - in particular water - are suspected to play in the formation and evolution of life. This project concerns the synthesis and characterisation of liquid-filled nanometre and micrometre sized particles for the simulation of cosmic dust in hypervelocity (km/s) impact experiments. The goal is to construct thin silica and/or polymer shells around a water, or volatile organic, core. These particles will then be used in hypervelocity impact experiments, simulating the interaction of surfaces and atmospheres with icy and volatile-rich cosmic dust particles. Particles will be accelerated using the only Light Gas Gun in Europe (located at the University of Kent, UK) capable of firing icy particles, as well as the most advanced Van de Graff dust accelerator facility in Europe (Heidelberg, Germany). The project is a collaboration between UK and German researchers, based in Canterbury and Sheffield (UK), Heidelberg, Stuttgart and Leipzig (Germany). It is envisaged that the particles produced by this project will be available for use by researchers from across Europe, as well as international collaborators. The project will build a framework for a pan-European network of researchers in cosmic dust impact science, including partners in Germany and the UK. The researcher will move from Germany to the UK, receiving training in research and analytical techniques (e.g. research management, light gas gun usage, microscopy, spectroscopy and particle characterisation). Further quantitative training will be provided in the form of a postgraduate level qualification in university teaching and research supervision (PGCHE), a transferable skill which will si
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Vacuum Medical Device for Safe and Gentle Cervix Grasping Gynecological Applications' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

For years, gynecologist practices related to Intra-Uterine Contraceptive Device (IUD) insertions, curettage and several other common indications, have featured poor care and low attention to female patients.The use of the Tenaculum, grasping and pulling on the cervix, inside the vaginal cavity, proved to be painful and traumatic for 84% of the women, and eventually to trigger lesions and bleeding in 29% of the patients, as well as cross-contamination in 5-10% of the women. These disadvantages refrain the use of IUD contraceptive which exacerbates the unintended pregnancies, sized yearly in 85 mills and representing billions of euros in social costs worldwide.In response, we have developed Aspivix, a new disruptive gynecological device that reduces the pain and eradicates the bleeding during the exploration procedure. Our patented device will replace the Tenaculum forceps, unchanged for over 100 years, to provide gynecologists an easy-to-use device where gentle and firm cervix uterus grasping and traction is needed. Thus, our device will facilitate the adoption of IUD, which could avoid up to 8% of unintended pregnancies and reduce derived social costs. Besides, Aspivix is intended for a single use which prevents the risk of contamination and cross-infection. Overall, Aspivix has the potential to shorten the intervention procedure (2 steps instead 7), which will represent for the physician a 28% economic benefit. As result, Aspivix will fulfill the needs of more than 64 M of women worldwide/year, a market that is projected to grow at a CAGR2016-2021 of ~6.5% due to the high demand of IUD insertions and is valued in more than €385M.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'PRODUCTION AND DISTRIBUTION OF THERMAL ENERGY ON UNIVERSAL EXHIBITION SITE LISBON 1998' to be submitted under Fourth Framework.

assistant: **Abstract**

The project for the Production and Distribution of Thermal Energy at the EXPO'98 area is involved on a global strategy for the rational use of energy. Its purpose is to satisfy the needs of thermal comfort of the building inhabitants and other consumers. The feasibility of the system, the comfort use, the reduction of primary energy consumption and the environmental impact are purposes to be reached.The central production will enable to satisfy :* at first, the needs of two buildings (OCEANARIO" and "VILA EXPO" - May 1997),* afterwards, the needs of EXPO'98 and all the buildings, in accordance with the connections, and at latest, by the end of March 1998,* finally, after the exhibition, the other needs of EXPO'98 area, foreseen until the end of the concession.The high energy performance expected and the reduction of the maintenance costs are also a major aim, the spreading of this system to other large European cities are an important advantage.L%The expected main results are quantitative and qualitative:QUANTITATIVE : * Primary energy saving : 1st year (1999) 6.037 equivalent metric tons of oil/year * CO2 emissions reduction : 7,5 Mt/year (49%) * SOx emissions reduction : 0,86 Mt/year (99%)(which are the difference of values between a classical air conditioning system and the CLIMAESPACO proposed centralized way).QUALITATIVE: * Suppression of both smoke and steam plumes, * Suppression of CFC and HCFC, * Safeguarding of building aesthetics, * Service reliability and technical assistance 24 h per day 365 days per year.Beyond the event, PARQUE EXPO'98 is planning to build around the site an advanced business district as a showcase of new technologies and to renovate East LISBON and make a contribution to development in PORTUGAL. To this end PARQUE EXPO'98 suggests an over
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Development of A Method for Analysis of Creep Behaviour of Welded Rotating Components of High Temperature Applications Based on Eigenstrain Theory' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The need for high-quality joints in the aerospace industry has fostered the use of inertia friction welding for nickel-based super-alloy components. This technique provides improvements in the joint quality when compared to the fusion welding techniques, but understanding on the effect of residual stress on creep deformation of welded components is limited. The proposed research aims to develop new computational and numerical tools to reproduce the residual stress field in inertia welded components in the as-welded and post-weld heat treated conditions. This innovative approach will meet experimental data with the eigenstrain theory to reconstruct stress fields in large scales and provide a realistic model to understand creep behavior of materials under complex loading and high-temperature conditions. To achieve this target, the eigenstrain theory will be used with experimental measurements. This will allow modeling of complex geometries with high accuracy. The study will be composed of three stages which are data collection for eigenstrain reconstruction method, creating a model for eigenstrain reconstruction process and development of a visco-plastic model for investigating creep behavior of post weld heat treated samples. Results and data created in the first two stages will be used to create the visco-plastic model. Experiments will be performed using diffraction and contour methods and numerical models will be created using ABAQUS commercial finite element software. All research, management, training, dissemination, public engagement, and communication activities are scheduled into a 2 years work plan. The developed methodology is expected to provide a better understanding of creep behavior, to be used by other researcher and be beneficial for industry on the devel
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'NANOSCALE ANALYSIS OF PROTEIN ISLANDS ON LYMPHOCYTES' (NANO-ISLANDS) under Seventh Framework.

assistant: **Objectives**

To detect foreign invaders and to communicate with other cells of the immune system, B lymphocytes carry a multitude of receptor proteins on their surface. In the past, it was thought that most of these receptors are randomly distributed on the cell surface and only become organized upon lymphocyte activation. Recent studies showed, however, that many of these surface proteins are pre-organized in nanoscale protein islands (here called nano-islands) with a size of 50-150 nanometer (nm). We have developed a Fab-proximity ligation assay (Fab-PLA) which allows us to study the organization of membrane proteins at 10-20 nm distances. With this method, we discovered that the B cell antigen receptor (BCR) of the classes IgM and IgD are located in different class-specific nano-islands.Due to the technical limitations of classical biochemistry (detergent lysis), light microscopy (diffraction limit of 250 nm) and electron microscopy (fixation artifacts), the nanoscale organization of membrane proteins is not well studied. With the Fab-PLA method, we can, for the first time, explore this unknown 200-20 nm space and analyze the composition and stability of the different nano-islands on the B cell surface. We also will develop new methods such as proximity biotinylation and proximity proteomics to better study these nanostructures and learn more about their role in B lymphocyte activation and human diseases such as lymphomas and autoimmune diseases.Although more than 50% of all drugs target membrane proteins, the nanoscale organization of these proteins is poorly characterized. To learn more about the nano-islands organization of membrane proteins is thus of utmost importance for a better understanding of the action of these drug treatments and to improve them. Our study may also pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Pattern analysis, statistical modelling and computational Learning', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

The objective is to build a Europe-wide Distributed Institute which will pioneer principled methods of pattern analysis, statistical modelling, and computational learning as core enabling technologies for multi-modal interfaces that are capable of natural and seamless interaction with and among individual human users.At each stage in the process, machine learning has a crucial role to play. It is proving an increasingly important tool in Machine Vision, Speech, Haptics, Brain Computer Interfaces Information Extraction and Natural Language Processing; it provides a uniform methodology for multi-modal integration; it is an invaluable tool in information extraction; while on-line learning provides the techniques needed for adaptively modelling the requirements of individual users.Though machine learning has such potential to improve the quality of multi-modal interfaces, significant advances are needed, in both the fundamental techniques and their tailoring to the various aspects of the applications, before this vision can become a reality. We therefore propose to establish an inter-disciplinary Europe-wide Distributed Institute of Pattern Analysis, Statistical Modelling, and Computational Learning. The Institute will foster interaction between groups working on fundamental analysis including statisticians and learning theorists; algorithms groups including members of the non-linear programming community; and groups in machine vision, speech, haptics, brain-computer interfaces, natural language processing, information-retrieval, textual information processing and user modelling for computer-human interaction, groups that will act as bridges to the application domains and end users.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Novel Materials and Processing Strategy for Oesophageal Stents'.

assistant: **Innovation**

There is a need for addressing the condition and symptoms associated with oesophageal cancer in Europe and Worldwide. Around 5-10 in every 1000 men and around 1 in every 1000 women will develop oesophageal cancer during their lifetime, with care being mainly palliative via oesophageal stents, rather than therapeutic. This form of cancer has been demonstrated to be on the increase in Europe due to the growth in cases of adenocarcinomas, which in turn can be linked to the increase in alcohol consumption and obesity in western countries.There are problems associated with the current palliative treatments available for oesophageal cancer. Namely, tumour ingrowth into the stent, hyperplasic tissue formation and migration of the device. In the past few years, the scientific development of oesophageal stents has been on an increase However, the creation of a therapeutic device rather than merely a palliative one is still unavailable. Such an advancement would cause a major shift in the treatment of oesophageal cancer, allowing the state of the art to be pushed into new realms.This proposal will address the ultimate goal of treating the condition of oesophageal cancer with the aim of restoring oesophageal function and returning the lives of sufferers to near-normal states. This will be achieved by the creation of a novel drug-eluting, shape memory, degradable composite stent using the experience of the researcher (Dr Judith Juhasz) and supervisor (Professor Aldo Boccaccini) at the Institute of Biomaterials in the University of Erlangen-Nuremberg, Germany. Creation of this novel material within this Marie Curie Intra-European Fellowship will advance the understanding of stent design for the treatment of oesophageal cancer and will put Europe in a leading position as a competitor