RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Protest as a Democracy Test: Protest Culture under Transformation and as a Transformative Power'.

assistant: **Objectives**

There is a steady trend of global democratic decline (de-democratization), transforming political opportunity structures and creating new knowledge gaps about how protest cultures evolve and adapt to changing contexts. Addressing this gap, the project's aim is twofold: First, to reveal whether and how ongoing de-democratization processes affect patterns of protest culture and how these effects vary according to democracy (consolidated, new and developing); second, to trace whether and how affected patterns of protest culture influence the state of democracy in target countries, by focusing on representation as inclusion of citizen preferences in political agendas. Research findings will shed light on two dimensions of protest culture, particularly its internal capacity and its external constraints. This will be done via analyzing historical contexts of variations in protest cultures across different types of democracy, factors intersecting to trigger or shape pro-democratic/anti-democratic protests, political elite manipulation of legal and discursive frames to curtail public discontent, role of traditional and social media creating opportunities or obstacles for actors engaged in contentious politics, generational differences in perceptions of and participation patterns in protest culture, and finally, influence of protest culture itself on the state of democracy through representation as an outcome of civic participation. The interdisciplinary project relies on methodological pluralism and integrates: desk research and legal analysis, biographical narrative interviews and focus groups, quantitative and qualitative content analysis, critical discourse analysis and visual analysis, network analysis for mapping actor-discourse coalitions, and Q methodology. The project r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Antibody mediated clearance of senescent cells for treatment of COPD' (2014-2020) under Horizon 2020.

assistant: **Objectives**

Chronic Obstructive Pulmonary Disease (COPD) is a group of chronic diseases characterized by airflow limitations in the lung.  COPD is a critical international health problem. It is estimated to affect up to 600 million people worldwide and by 2020 it will become the third most frequent cause of death.  In Europe alone, COPD affects up to 10% of people (i.e. more people than breast cancer and diabetes) and it takes the life of around 300,000 Europeans each year. Up to date, COPD has no cure as current treatments fail to halt the long-term decline in lung function. They are only able to delay its progression. Those treatments however, are associated with a variety of side effects some of which can be acute and even life threatening. Thus, COPD remains a disease with a significant unmet medical need.In this project (acronymed AbCURE_COPD) we intend to carry out a set of necessary activities for the evaluation of a potentially groundbreaking approach for treating COPD.  Our approach is focusing on antibody-mediated clearance of senescent cells which accumulate in tissues with age and contribute to multiple age-related diseases, including COPD.  The goal of the PoC project is two-fold. (1) The first goal is to establish the technical feasibility of our idea by testing the effect of senescence-specific antibodies on COPD development and progression by implementing COPD mouse model we developed. (2) The second goal is to establish the business feasibility of our revolutionary approach by taking the necessary steps towards its commercialization, focusing on the creation of strategic alliances with key private sector companies.  We firmly believe that with our approach we can significantly extend the health span and improve the quality of life of COPD patients.  Equally importa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Multi-wavelength study of accretion onto black holes and its evolution during cosmic times', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The beginning of this century can be considered a golden age for X-ray astronomy, with the launch of XMM-Newton, Chandra and Suzaku, three cornerstones of the ESA, NASA and JAXA space programs. These observatories, although more than 10yr old, still deliver excellent science and X-ray astronomy now leads many fields of astronomical investigation. However, only small-medium class X-ray missions are planned to be launched in the next 10-15yr, thus shrinking the space for new discoveries in X-rays alone.The two years at MPE will allow to diversify my scientific expertise by: i) expanding my research field into: a) Optical-Infra Red (IR) bands; b) evolution of Active Galactic Nuclei (AGN) variability through cosmic time; ii) being granted access to Optical-IR facilities and new X-ray missions. The proposed project will allow to:1) measure the evolution of AGN variability over cosmic time using large AGN samples, thus also assessing whether AGN can be used as standard candles;2) measure SgrA*'s duty cycle, its past activity, the Molecular Cloud (MC) Galactic Center (GC) distribution, the level of GC cosmic rays, the irradiation induced MC chemistry;3) if SgrA* will go into outburst (a gas cloud will reach SgrA* in mid 2013) we will lead the X-ray investigation of this major event (e.g. the switching on of an AGN, jet-disc creation) that will remain in astronomy records;4) link (thanks to NuSTAR, the new NASA X-ray mission) the variability properties of the Compton reflection hump, the FeK line and the soft excess in AGN, to finally understand the origin of these components;5) monitoring the evolution of the cross-correlation function and the spectral energy distribution, during an entire Galactic Black Hole (GBH) outburst, to echo-map and determine the transformation of the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Promotion of Public Procurement of Innovation for Resource Efficiency and Waste Treatment' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

PPI4Waste is based on an integrated approach which will permit to define needs, targets, improvement of functional performances, and monitor the complete cycle of preparation activities for PPI process to be implemented in the waste sector, while making know-how on procedures for innovation procurement widely available through the establishment of buyer’s group, making state-of-the-art solutions accessible to other procurers, capacity building and assessment of feasibility plan of uptaking PPI in the waste sector.This 30-month project, whose workplan has a concise structure that supports the workflow to achieve its main aim: The overall objective of the project is to achieve resource efficiency, sustainable waste management and sustainable consumption throughout Europe by increasing the use of innovative public procurement through coordinated a structured and coordination action of networking, capacity building, and dissemination.The cornerstone of the project is how to boost resource efficiency through PPI, on the basis of the waste hierarchy and the establishment of the buyer’s group of public procurers in the first phase of the project will permit to achieve all objectives towards the reinforcement of early deployment of eco-innovative solutions for resource efficiency and waste management through joint or coordinated PPI processes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Improvement of freezing tolerance in baker's yeast by adaptive evolution' (2002-2006).

assistant: **Concept**

Commercial baker's yeasts are domesticated strains of S. cerevisiae that have been selected and optimised for baking applications. Nevertheless, there are still important traits that are far from optimal. In particular, toleranceto freezing is clearly in adequate, being the main factor that limits the expansion and development of frozen-dough technology. In this scenario, our proposal aims to increase our knowledge on the cellular factors that determine the freeze tolerance of baker's yeast and to explore strategies to improve this commercially important trait.In particular, we will focus our attention to the development of freeze-tolerant bakers' yeast by adaptive evolution, as an alternative to the DNA recombinant technology. New strains with improved freezing tolerance will be obtained from commercially available baker's yeast by long-term chemostat cultivation under sub-optimal temperatures.The molecular basis of the freeze-resistance in the new evolved strains will be determined with the use of genomics tools. Finally, the quality of bread and pastry obtained from frozen dough prepared with freeze-tolerant yeast strains will be tested under industrial conditions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'An experimental investigation of the interrelationships between reactivity, deformability and permeability during the serpentinization of olivine'.

assistant: **Objectives**

Research objectives and content  This project draws its attention to the interrelationships between reaction kinetics, mechanical properties and permeability of olivine aggregates undergoing serpentinization. Using high pressure and temperature experiments, the kinetics of chemical reactions, the development of reaction-induced fracturing, and the changes in permeability can be measured 'in situ' for providing a quantitative basis for characterizing the mechanical properties of rocks undergoing a fluid-enhanced metamorphism. The project will be done at the Rock and Ice Physics Laboratory, University College London. The potential for developing feedback relationships between reactivity, deformability and permeability is particularly clear in metamorphic systems involving fluids where the reaction involves a sufficient volume increase to induce fractures. Under such circumstances the fractures provide fresh surfaces on which the reaction can proceed further enhancing the potential for fluids to move through the system modifying the mechanical properties of the reacting system. The research proposed seeks to determine the strength of these feedback relationships by controlling separately, under isostatic conditions the reaction kinetics, reaction-induced fracturing and permeability during the serpentinization of olivine. The results will be used as a basis for monitoring the progress of the reaction and interpreting the accompanying evolution in mechanical properties during deformation experiments at the reaction conditions. Training content (objective, benefit and expected impact) In coming to the Rock and Ice Physics Laboratory at University College London I will very substantially increase the range of my experimental expertise to include the measurement of acoustic pro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Improvement of the quality of supply in distributed generation networks through the integrated application of power electronic techniques (DGFACTS)' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

The aim of the DGFACTS project is to solve the set of quality of supply (QS) problems arising from the integration of Distributed Generation (DG) into the electric Distribution networks. Current power quality, efficiency and reliability, ensured by the utilities and supported by the use of powerful conventional generators, could dramatically decrease because of a more spread responsibility on the Grid Quality Management and the technical shortcomings because of the characteristics of the DG-units and the Distributed Generation Networks themselves. The project will introduce the use of the FACTS concept in distribution systems by designing a set of modular systems (DGFACTS) to optimally improve the stability and QS of each distribution network with high DG+RES penetration. In addition, the project will face the management of QS responsibilities in this new scenario.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'ReproTag - Targeting reproductive traits for more efficient forage grass breeding' to be submitted under Seventh Framework.

assistant: **Abstract**

Grassland is a key component of a diverse but productive European agroecosystem and contributes to sustainable feed and food production worldwide. Novel grass breeding schemes based on a more efficient exploitation of heterosis have the potential to substantially outperform current forage grass varieties in terms of biomass yield, resistance and tolerance to biotic and abiotic stresses. However, current attempts to produce hybrids in forage crops are limited by self-incompatibility (SI), a genetic mechanism that efficiently promotes cross pollination, and the inability to efficiently control pollination for hybrid seed production at commercial quantities.The overall goal of the research is to identify and target grass reproductive traits that can be utilized in hybrid breeding schemes and finally lead to improved productivity of forage and turf grasses. The proposed research will focus on the two-locus SI system, fertility restoring self-compatibility loci (SC), cytoplasmic male sterility (CMS) mechanisms and double haploid (DH) induction in perennial ryegrass (Lolium perenne L.).This goal will be achieved by a unique cross-disciplinary approach combining expertise in hybrid breeding available at the host institution, state of the art genetic and genomic tools available through the collaboration partner from Aarhus University, Denmark, and excellent genetic resources available from Molecular Ecology and Fodder Crop Breeding at Agroscope Reckenholz-Tänikon Research Station (ART).For the host institution, the proposed research will strengthen the research strategy to improve aspects of the “World Food Systems” and complement the teaching portfolio by adding valuable education elements based on molecular breeding strategies. Close interaction of collaborating parties will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Eco-evolutionary dynamics in urban ponds under artificial light at night' (2021-2027) targeting Horizon Europe.

assistant: **Abstract**

Artificial light at night (ALAN) is a ubiquitous feature of urbanization, and increases globally. Recent work, mainly conducted on terrestrial systems, reveals negative biological impacts of ALAN. If experienced in aquatic systems, ALAN may disrupt the delicate food web dynamics in urban ponds, with potentially detrimental consequences such as the occurrence of (toxic) algal blooms, which can cause serious harm to animals, including humans. Zooplankton, key components of freshwater systems, exert strong control over algal growth, but this crucially depends on their diel vertical migration (DVM) patterns (i.e. migrating to the bottom during day, and to the surface during night) – a dynamic known to be disrupted by ALAN. To date, very little is known about potential evolutionary adaptations in response to ALAN, whereas is has never been studied whether such adaptations can shape the ecology of ponds, e.g. top-down control of algae (so-called ‘eco-evolutionary feedbacks’). With the proposed project, I aim to study whether i) ALAN influences trait distributions and DVM of water flea zooplankton communities in urban ponds, ii) water fleas originating from these ponds have evolved genetic adaptations to ALAN in key ecologically relevant traits, and iii) ALAN-driven genetic trait changes influence the ecology of urban ponds (i.e. top-down control of algae). To achieve these aims, I will conduct a comprehensive field study, followed by laboratory common-garden experiments with ALAN-manipulation, and finally a field transplant DVM experiment. By integrating these results within an eco-evolutionary modelling framework, I will test for ecological consequences of evolutionary adaptations in one or multiple water flea species to ALAN. Given the rapid rate of urbanization, findings o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Main Uses of the Grey mullet as Indicator of Littoral environmental changes' (MUGIL) targeting Sixth Framework.

assistant: **Abstract**

The particular status of estuaries, deltas and lagoons in coastal areas, located at the interface between sea and river influences, results in highly variable environmental and ecological conditions that shift over space and time. The combined effects of climatic changes and human activities have tremendous consequences on these ecosystems.The conservation of these environments is one of the biggest challenges for humanity. In order to achieve an integrated management, researchers, ecologists and managers try to select relevant indicators, which could be used as tracers of the state of estuarine areas. These indicators are generally chosen among living species or physicochemical parameters or a combination of both. Among the fish species living in estuarine ecosystems, very few are able to live in a wide diversity of habitats. It is yet the case of one peculiar species, Mugil cephalus (Mugilidae), which is found worldwide and is cosmopolitan in almost all tropical coastal estuarine zones, but also in temperate ones. This species is able to live and reproduce in widely different habitats.The mechanisms, which are involved in this process, are poorly known or are studied separately in each area. Moreover this species and related ones support important fisheries, especially in developing countries. The aim of the MUGIL project is to build an observation network and to coordinate across the world the action of using this species as an indicator of the state of estuarine areas by observing the population genetics, the life history trait variations and the physiological responses to salinity or pollution.The project covers four world areas (Europe, Africa, Asia, America) and involves collaborators from southern Europe (France, Spain, Greece) and tropical countries (Mexico, Se
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Early treatment of Atrial fibrillation for Stroke prevention Trial in acute STROKE' (EAST-STROKE).

assistant: **Concept**

Patients with acute ischemic stroke and atrial fibrillation are at high risk for recurrent stroke and other adverse cardiovascular complications. Usual care comprises oral anticoagulation and rate control. However, it is unclear, whether existing interventions for early rhythm control reduce the risk of adverse cardiovascular outcomes in these vulnerable patients. EAST-STROKE (Early treatment of Atrial fibrillation for Stroke prevention Trial in acute STROKE) is set out to tackle and reduce the individual and societal burden of death and disability by providing evidence for effective secondary prevention using readily available interventions in these patients. To this end, EAST-STROKE is an investigator-initiated, prospective, randomized, open, blinded endpoint assessment (PROBE) multi- trial to test whether early rhythm control therapy prevents adverse cardiovascular outcome in patients with acute ischemic stroke and atrial fibrillation compared to usual care. Up to 1,746 patients will be enrolled. Trial organisation relies on a network of experienced clinical researchers, patient representatives and Health Economics experts. Outcome evaluation will involve a comprehensive array of clinical and safety parameters, health and socio-economic outcomes including patient reported outcome measures. We will also perform cost-effectiveness analyses to address the needs of payers and ease implementation into reimbursement schemes. The project addresses a major health burden and will provide evidence for more effective prevention of adverse outcomes in an area of high public health need. We expect that the results of EAST-STROKE will be implemented rapidly throughout Europe, will support health equity, and will prevent more than 150 thousand recurrent strokes or adverse cardiovas