RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Design for all for eInclusion' in the context of a Sixth Framework call.

assistant: **Objectives**

The CA aims to support networking for Design for All in Europe, in order to promote inclusion by advancing DfA practices in the Information Society, and in particular though contribution to the efforts of EDeAN towards the implementation of the eInclusion priorities and the eEurope 2005 - 2010 Action Plans. On the basis of the creation and development of innovative Design for All communities, like EDeAN, it is now uniquely possible to establish thoroughly those aspects that work best and those which can be either refined or replaced, better to achieve the EU's goals of eInclusion through DfA.Therefore, the core of this CA is to explore and evaluate the EDeAN environment in order to create enhanced coordination actions to achieve new levels of eInclusion, coherence, effectiveness and efficiency to boost the role of the EU in eInclusion. From a technological perspective, the main aim of CA DfA@eInclusion is to support and enhance the networking and cooperation activities of the European Design for All (DfA) community, emphasizing the overall target of eInclusion, which is to ensure that future technological developments are user-based and, therefore, take into account the needs and requirements of all citizens, including people with disabilities and elderly people. Towards this end, the proposed CA builds upon, supports and extends past, and ongoing initiatives, such as the European Design for All e-accessibility Network" - EdeAN, as well as and some IST funded projects that have been realized in the context of the EC FP 5 (e.g.,IST-2001-38833 D4ALLnet, IST- 2001-38786 IDCnet)."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Transition to safe & sustainable food systems through new & innovative detection methods & digital solutions for plant-based products derived from new genomic techniques, under a co-creation approach' (DARWIN).

assistant: **Concept**

DARWIN aims to contribute to a fair, healthy, safe and environmentally friendly food system by co-developing an innovative detection strategy by integrating targeted analytical PCR-based methods, untargeted sequencing methods, and digital solutions. A new generation of innovative and reliable DNA-based analytical detection methods, ranging from enhanced PCR methods for NGT detection, identification and quantification in single and multi-target systems, to untargeted sequencing methods related to whole-genome sequencing, laser capture microdissection-based sequencing and high throughput metagenomics sequencing for NGT screening and characterization. DARWIN will bring a cutting-edge approach developing genetic fingerprints using artificial intelligence to overcome challenges related to event-specific targeted methods, unambiguously identifying specific NGT lines. DARWIN also brings innovation in the new application of digital solutions such as data spaces and documentation-based screening to increase the data evidence to NGTs; blockchains to enable transparent and traceable detection along the food chain; AI models; and a Decision Support System to improve accuracy and support the selection of the best fit for purpose detection methods. DARWIN will reach TRL4-5 though validation including in-house, transferability and full trials, and presenting 3 cases representative of real situations relevant for NGT products in the EU agri-food market. After methods validation and the definition of a clear oriented detection strategy, DARWIN will theoretically extrapolate its finding to more complex scenarios encountering the diversity of NGT lines and food products that might reach EU markets. All this, under an interdisciplinary co-creation ecosystem based on Responsible Research an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Melt Spun and Sintered Metal Fibre Networks for Lead-Acid Battery Advancement' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Climate change is one of the largest threats facing the world today. At the forefront of combating this issue are low carbon technologies. Recently, HEV (Hybrid Electric Vehicles) have come forward as the most achievable solution of the moment. At present, HEV use expensive Lithium ion and NiM batteries due to their high power to weight ratio. Lead-acid batteries are a cheaper option, but due to their lower power to weight ratio they are not used.The MEMLAB project aims to solve this through the development of lightweight electrodes for use in lead-acid batteries. The project will use state-of-the-art fibre production technology to create titanium and aluminium fibre networks. These will be coated in lead and lead oxide. The objective is to achieve a greater than 50% reduction in the overall weight of a lead-acid battery thereby significantly increasing their power to weight ratio making them a realistic alternative for application in hybrid electric vehicles.In addition to application in the hybrid electric vehicle market, the replacement of standard lead-acid batteries, containing large and heavy quantities of lead, by lightweight lead-acid batteries will also lead to a significant reduction in the polluting effect of road-going vehicles due to the large quantity of vehicles in use. The number of lead-acid batteries currently manufactured in Europe is approximately 70 million per year.The project consortium has been specifically constructed so that the research partners deliver the technical research required by the SME consortium partners. Successful completion of project MEMLAB will significantly strengthen the competitive position of the participating SMEs by both opening new markets, hybrid electric vehicles, and expanding opportunities in existing markets, lead-a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Light-induced synthesis of protein-drug conjugates for imaging and therapy', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The ability to functionalise a biologically active protein with a range of different cargo molecules is crucial to accessing new tools for use in fundamental science and clinical medicine. For instance, antibody-conjugates that graft reporter molecules including fluorescent tags or radioactive metal ion chelates play vital roles in diagnostic imaging with optical and nuclear medicine techniques like positron emission tomography (PET). State-of-the-art advances in chemotherapy also take advantage of the biophysical properties of antibodies in the design of highly potent antibody-drug conjugates (ADCs) that facilitate specific delivery and uptake of cytotoxic or radiotoxic payloads to disease lesions. Surprisingly, almost all existing methods to produce protein-conjugates rely on thermally-mediated coupling chemistries. In PhotoPHARMA, the goal is to break away from the convention of using heat to drive protein functionalisation by designing new photochemical reagents that are activated by the absorption of light. Light-induced activation has the potential to solve many of the practical issues encountered in the synthesis of radiolabelled antibodies and other protein-conjugates. The work encompasses 4 main Objectives:  Objective 1. Explore the biochemical scope of light-induced reactions for bimolecular protein-ligation  Objective 2. Synthesis, characterisation and biological studies of photo(radio)labelled antibodies for use in diagnostic imaging and therapy  Objective 3. Develop automated technologies for photoradiochemical synthesis of 89Zr-antibodies  Objective 4. Establish the GLP-synthesis and Chemistry, Manufacturing and Controls (CMC) for future translation of photoradiolabelled 89Zr-antibodies to the clinic  The long-term goals are to facilitate the synthesis and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Feasibility assessment on the GreenFlux Service  Operations Platform for Smart Charging (GSOP-SC)'.

assistant: **Concept**

The objective of this proposal is to explore the business cases for the implementation of GreenFlux’s Service & Operations Platform for  Smart Charging (GSOP-SC) in several European urban areas. This will contribute to the introduction of a full service and independent software solution, connectable with any (PH)EV charge protocol, that enables any EV to plug into any electricity grid in Europe, and provide an efficient platform for EV transaction and energy management. Such a platform will facilitate a complete chain optimization, from EV user to network operator, offering excellent commercial prospects.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'PRECISION-RA: Precision Immunotherapy for Rheumatoid Arthritis' (PRECISION-RA), addressing dissemination and exploitation.

assistant: **Impact**

Rheumatoid arthritis (RA) causes chronic pain and inflammation when the human immune system erroneously attacks healthy joint tissue. In over 70% of cases, B cells secrete anti-citrullinated protein antibodies (ACPAs), which are disease-causing autoreactive antibodies. Current treatments are focussed on dampening the whole immune system. These therapies can suppress or kill all B cells, not only the ACPA-secreting, autoreactive ones, leading to a compromised immune system, increased risk of infection and numerous severe side effects. These treatments are also not curative. We have developed a method to target and kill only the ACPA-specific autoreactive B cells, leaving the rest of the B cell population, and human immune system, intact. This represents an exciting new treatment method for RA. By capitalising on our deep understanding of human complement immunobiology and expertise in synthetic biology, we have developed a C1-activating bispecific (CAB). CAB comprises an engineered antibody fragment that binds to the first complement component, C1, which can induce cell killing when targeted to cell surfaces. We have conjugated CAB to a targeting moiety that directs complement to kill only B cells that secrete the autoreactive antibodies. Our preliminary data demonstrates remarkable cell specificity, as CAB destroys only the ACPA-specific autoreactive B cells in a large population of diverse cell types. Here, we will apply our established protocols and expertise to generate important preclinical data, which includes humanised animal models to exemplify when and how CAB can be used to treat RA. This data will be used to strengthen our IP position, engage with clinical, industrial and patient stakeholders, and develop a robust business case to take CAB forward into clinica
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Signaturit - The smartest e-Signature solution to send and sign documents on the go' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Signaturit - The smartest e-Signature solution to send and sign documents on the go.Electronic signatures have been regulated in most of the developed countries, including the European Union and the United States of America, to permite their legal use. Signature is a service that allows to the user handwriting signature of documents through any mobil device in a digitized format. It allows the receiver to sign an attached document received by email.After the session logout, the service automatically converts the attachments to a PDF document that is signad with an electronic signature, sealed and with time stamping.It is a multiplatform application, meaning that it does not requiere any specific device for its use (it only requires a device with a touchscreen). Just a valid email adress and Internet connection on the mobile device are needed for working. It is completely independent from email management software, Wen browsers, etc. We identify the signer in a unique way and certify the electronic evidences generated during the signing process.The purpose of Signaturit is to leader the online world in term of the digital signature of documents, providing the highest possible legal validity to the process and providing to the service the consideration of advanced electronic signatgure according to the definition established by the Act 59/2003 on electronic signature and providing legally valid probative evidence in the process.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Control of vibration from underground rail traffic', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

Electrified underground rail systems provide the apparent solution to mass transport of people in cities but their future success and growth require a high degree of eco-efficiency. Metro rail systems cause vibrations, which create noise disturbance in adjacent habitation. CONVURT is aimed at creating the innovative tools where ground borne vibrations can be predicted and minimised. The proposal is to create a validated computer based prediction model as well as prototype innovative vibration reducing products, both able to be applied to world-wide sales. CONVURT will also develop novel monitoring and maintenance techniques that will prevent deterioration of vibration performance with time. The project will make unique, invaluable input to the development of ISO rail noise standards and produce 'Best Practice Guidelines'.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Odour-GPCRs based technology for detection and stratification of cancer: Prostate Cancer Smell Print as first vertical market'.

assistant: **Concept**

PCSP project is born out of the unique expertise developed after years of R&D at Canvax Biotech, and aims at transferring a technology to cover an unmet clinical need, accurate diagnosis of prostate cancer (PCa). Canvax owns a unique set of patented technologies: i) high expression of olfactory receptors (oGPCRs) in heterologous cells, ii) coupling to a signalling cascade and iii) readable fluorescent assays to quantify oGPCR activation. Canvax is producing an array of cells expressing oGPCRs that could be used to detect several types of cancer, including PCa, by detecting cancer-associated volatile organic compounds in urine. The technology is currently being tested in a PCa clinical trial. PCa detection has been widely carried out using the prostate specific antigen test. However, its low accuracy resulted in a high percentage of false positives and a still appreciable amount of false negatives. Several recent studies showed that trained dogs could detect PCa from urine samples with the higher accuracy. However, the use of dogs in clinic is difficult and non-scalable. Canvax PCSP test resembles a dog nose that pretends to be a universal screening method for PCa-type discrimination identifying, in simple urine test, patients in need of further, more invasive diagnostic procedures with higher accuracy than current standard of care, saving stress, anxiety and unnecessary risky procedures. The easy use and low cost of this technology makes it ideal for broad adoption. Different scenarios have been described for market penetration and would be subject of the feasibility study during phase I: Smell print definition, regulatory and market permits acquisition, clinical trial design, identification of best-selling points, EU extension and financial costs will be analysed. The
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Action for advanced Drivers assistance and Vehicle control system Implementation, Standardisation, Optimum use of the Road network and Safety' (ADVISORS) under Fifth Framework.

assistant: **Objectives**

Research and development have created a range of advanced driver assistance systems (ADAS) that may facilitate the tasks of drivers in the growing complexity of traffic conditions. Appropriate ADAS will be selected from a problem-focussed angle and analysed in a multidisciplinary approach, in order to gain new policy insights. All the stages for a potential breakthrough of ADAS will be investigated: the market conditions, the impacts on driving behaviour, road safety and environment, role of the public regulator, public acceptance, implementation strategies etc. Assessment methodologies will be developed and applied in order to deliver empirical evidence. This evidence together with questionnaire surveys will fit into a developed division scheme. This approach leads to an integrated framework suited for designing road safety policies to help realise suitable ADAS. Policy recommendations and guidelines are put forward in the last stage.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Advancing Research and Training on Ageing, Place and Home' under Horizon Europe.

assistant: **Concept**

Ageing in place is critical to the future of ageing societies in Europe. Older people’s places are recognised as fundamental to long-term health and wellbeing outcomes - a fact that has been magnified during the Covid-19 pandemic. Yet, critically, almost a third of older people in Europe experience neighbourhood deprivation, a fifth encounter a lack of cohesion, a growing number are homeless, and approximately 3 million people continue to reside in institutional settings. There are significant concerns that efforts are failing to support ageing in place. With its development as a field fragmented across disciplines and sectors, and with few researchers equipped to tackle this fragmentation, innovation in research and policy risks stagnation. This is despite the renewed interest and urgency arising from the pandemic in de-institutionalizing later life residential experiences. HOMeAGE will institute an interdisciplinary, intersectoral and international programme of doctoral training and research that drives the development of new leaders in excellence for the advancement of evidence-based innovation on ageing in place. In tackling the three interconnected challenges of (1) needs and systems, (2) home and belonging and (3) rights and voice, HOMeAGE delivers a unique employability and skills development process for doctoral researchers (DRs) ensuring that they can lead the response to current research and policy deficits. HOMeAGE addresses significant demand for DRs who possess essential competencies to overcome challenges concerning Europe’s demographic transition, and ‘sticking points’ in its developing Silver Economy. HOMeAGE directly addresses the critical priority of enabling ‘older people to age in a place that is right for them’ within the WHO’s Global Strategy and A