RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Synaptic activity effects on local protein synthesis and spreading in high resolution' in the context of a Seventh Framework call.

assistant: **Objectives**

Understanding how and where our memory is stored is a long sought-after task. It is accepted that proteins at synapses play a role in capturing and maintaining memory. It is now clear that synapses possess the capacity for local protein synthesis, and that dendritic protein synthesis is required for many forms of long-term synaptic potentiation (LTP) and plasticity.It remains unclear over what spatial scale local translation can be regulated and stimulated. Moreover, the location of specific translation sites and the mechanisms by which local dendritic translation is activated are largely unknown.This study aims to determine the effect of single spine activity on local protein synthesis, and to decipher how varying levels of activation of the synapse activity in adjacent spines alters the dynamics and trafficking of newly synthesized proteins and to what extent (spatially and temporally).I will examine the correlation between local translation and the following neurobiological processes: synaptic plasticity, LTP, and the hypothesis of synaptic tagging and capturing. Their activation will be induced using different levels and patterns with high resolution glutamate uncaging, in adjacent or remote spines including on different dendritic branches.I propose to decipher the location of protein synthesis using fluorescent non-canonical amino acid tagging, which allows visualizing the protein synthesis in real time and in its natural site. I will address the translational regulation of exemplar proteins, of which their mRNAs were found to localize in dendrites, that represent neurotransmitter receptors (e.g. GluA1 or 2), scaffolding molecules (e.g. Shank, PSD-95), signaling molecules (e.g. CaMKIIa) and cytoskeletal elements (e.g. b-actin).Understanding the spatial and temporal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'European Medicines Research Training Network'.

assistant: **Innovation**

EMTRAIN is an essential element for the success of the IMI Education & Training (E&T) Call Topics in Europe (current and future). It will establish a pan-European platform of excellence for education and training covering the whole life-cycle of medicines from basic research through clinical development to pharmaco-vigilance. It will underpin the successful delivery of the current and future IMI-funded E&T projects, and by 2013 will have defined the IMI E&T vision.In collaboration with the different IMI E&T projects EMTRAIN will ensure trainingprogrammes are tailored in a coordinated way for current and future professionals involved in biomedical R&D. Flexibility and mobility of scientists is required to take advantage of the variety of opportunities at the pan-European level, and to understand European needs in biomedical and pharmaceutical medicines sciences. This capacity building project will build up the infrastructure for the other E&T projects and in future calls initiated by IMI, and will facilitate mobility between academia, industry, regulators, and other relevant stakeholders/potential employers.Based on extensive mapping of existing resources in Europe and on a gap and overlapanalysis, the consortium will develop and implement a strategy for pan-European expansion,for harmonisation and accreditation of continuing professional development (CPD) programmes in context of life-long learning under the umbrella of the IMI cross-project LifeTrain initiative (WP4/7). The consortium will provide a comprehensive registry of Master level and PhD programmes, as well as of CPD programmes. It will provide an overview of existing innovative learning concepts, tools and methodologies in conjunction with the other IMI E&T projects that will support the content for the IMI ed
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Modeling Erosion of scoria COnes to constrain Morphometry-based Ages.' (MECOMA).

assistant: **Innovation**

The MECOMA project aims to significantly improve hazard assessment of monogenetic volcanic fields (VF) by creating synergies between recent advances in landscape evolution modelling and the current understanding of scoria cones' volcanic structure and evolution. Assessing hazards from VF is more challenging than that of polygenetic volcanoes, as it requires understanding the spatiotemporal distribution of eruptions within the VF. Constraining temporal information is specifically challenging: radiometric dating of scoria cones (SC) provides, until now, the most ""accurate"" estimate of the date of their eruption, but it cannot be systematically applied to the hundreds or even thousands of SC within each of the many VF on Earth.  Morphometry-based dating of SC provides an alternative. Research has shown that following the cone's emplacement, the volcanic edifice's morphology changes due to erosive processes. Parameters measuring the decrease of slope angle, the degree of gully incision, and cone irregularity are key indicators of erosion that can be quantified from Digital Terrain Models (DTM). However, some questions still need to be answered to use morphometric indicators as age estimators, such as the control of SC size and climate conditions on the time evolution of morphometric indicators or the trade-offs between diffusive and advective erosion processes. MECOMA project seeks answers to those questions by implementing numerical models to simulate erosion on cones under controlled erosive conditions and linking the results with an analysis of the morphologies of radiometrically-dated scoria cones from different VF exposed to various climatic conditions. As an outcome, I expect to provide tools and clear guidelines that contribute to implementing morphometry-based dat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'IPv6 Deployment Support' (6DEPLOY).

assistant: **Innovation**

The purpose of the 6DEPLOY project is to support the deployment of IPv6 in (i) e-Infrastructure environments, thereby improving the use of existing research infrastructures for all fields of science and technology, (ii) FP7 projects, (iii) developing countries (Africa, Latin America, Asia and Eastern Europe), and (iv) more-commercial environments in Europe.6DEPLOY exploits the expertise and high quality training material from the 6DISS project, including presentations, the e-learning course and 2 testbeds that can be accessed remotely. Whilst continuing to offer basic training to organisations in Europe and developing countries it focuses on supporting real IPv6 deployments. It will maintain and update the 6DISS material and include new training media, and multiply its training effectiveness through courses which educate other trainers about the basics of IPv6, so that they can teach others (training trainers").The outreach to European industries and researchers and giving practical support for deployments are the 2 key new services offered by 6DEPLOY. Developing regions (in Europe and abroad) are often the early adopters of IPv6, given that they have less legacy IPv4 networks installed. Requests have already been received through contacts made in 6DISS for supporting deployments in a 16-site University campus in Argentina, and in less developed regions such as Colombia and Nigeria. These Case Studies will be used to gain valuable practical experience which will be brought back to support deployments within EC e-Infrastructure projects. The 6DEPLOY team will become the centre of European expertise regarding IPv6 deployment.This expertise will also be used to support more-commercial deployments in Europe, in industry branches such as Emergency Services, Health, Broadcast
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Inflammatory cells and their role in asthma and rheumatoid arthritis' in the context of a Fifth Framework call.

assistant: **Objectives**

Several specialised cell types contribute to the pathology associated with chronic inflammatory processes. The key cellular functions responsible either for the initiation of specific diseases or that contribute to the maintenance of the chronic phase remain obscure.This programme will focus on 4 particular cell types; mast cells, B cells, T cells and dendritic cells and will investigate the role played by specific functional properties of these in disease processes relevant to asthma and rheumatoid arthritis.One fellow will work with human and mouse dendritic cells investigating the regulation of function by cytokines and chemokines and the resulting effect on trafficking.A second fellow will investigate pro-inflammatory effects of chemokines on T cells.A third will focus on the regulation of immunoglobulin production by B cells at the level of regulatory cell surface molecules.A fourth will establish robust in vitro mast cell systems to investigate their potential to regulate functions of other key inflammatory cell types. Facilities available at GSK are state of the art, providing fully equipped labs support services. all the necessary reagents.Further facilities exist to enable unique reagent generation (MAbs, antisense etc). Both GSK and the research staff are fully committed to the training and support of young scientists who will benefit from a lively scientific environment and the structured training courses available to all staff.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Chaos in Parabolic Dynamics: Mixing, Rigidity, Spectra'.

assistant: **Objectives**

The theme of the proposal is the mathematical investigation of chaos (in particular ergodic and spectral properties) in parabolic dynamics, via analytic, geometric and probabilistic techniques. Parabolic dynamical systems are mathematical models of the many phenomena which display a ""slow"" form of chaotic evolution, in the sense that nearby trajectories diverge polynomially in time.  In contrast with the hyperbolic case and with the elliptic case, there is no general theory which describes parabolic dynamical systems. Only few classical examples are well understood.The research plan aims at bridging this gap, by studying new classes of parabolic systems and unexplored properties of classical ones. More precisely, I propose to study parabolic flows beyond the algebraic set-up and infinite measure-preserving parabolic systems, both of which are very virgin fields of research, and to attack open conjectures and questions on fine chaotic properties, such as spectra and rigidity, for area-preserving flows.  Moreover, connections between parabolic dynamics and respectively number theory, mathematical physics and probability will be explored. g New techniques, stemming from some recent breakthroughs in Teichmueller dynamics, spectral theory and infinite ergodic theory, will be developed.The proposed research will bring our knowledge significantly beyond the current state-of-the art, both in breadth and depth and will identify common features and mechanisms for chaos in parabolic systems. Understanding similar features and common geometric mechanisms responsible for mixing, rigidity and spectral properties of parabolic systems will provide important insight towards an universal theory of parabolic dynamics.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'EUropean Technology and Innovation Links - VAlorization of Chip PROcessing Technologies' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

The proposed Accompanying Measure aims at strengthening a restricted group of European SMEs who have developed innovative technologies for electronic chip manufacturing and control. These SMEs are capable of performing adaptive development of such technologies to meet needs outside their core market, in association with other industrial partners (SMEs and/or larger firms). Thus, they will become less sensitive to demand fluctuations within their main sector of activity through proper exploitation links in 6 countries (Belgium, France, Germany, Italy, The Netherlands, U.K.). Six consulting firms, with the help of the national contact points, will provide the support to build at least 12 CRAFT or RTD proposals, yielding new applications in promising sectors of growth, using an audit and project build-up toll based on the Euro-management procedures.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'HPCN integrated optimization strategies for increased engineering design complexity' under Fourth Framework.

assistant: **Concept**

DECISION aims to set up co-operative work on design optimisation problems of increased complexity.The combination of single or hybridised constrained optimisation tools with analysis solvers assembled on a HPCN platform targets innovative multidisciplinary engineering products. DECISION is a decision maker oriented tool for new product design optimisation. It provides an emergent technology for industrial competitiveness by significantly reducing design cycle and cost for new products.Complex design problems coming from three main industrial sectors - Aeronautics, Smart Materials and Forest Machinery - have been chosen to validate the efficiency of the design optimisation system and to provide quality with background of a wide range of optimised results.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Computer Aided Cryptography Engineering' to be submitted under Seventh Framework.

assistant: **Abstract**

Development of hardware devices and software products is facilitated by a design flow, and a set of tools (e.g., compilers and debuggers), which automate tasks normally performed by experienced, highly skilled developers. However, in both hardware and software examples the tools are generic since they seldom provide specific support for a particular domain. The goal of this project is to design, develop and deploy a toolbox that will support the specific domain of cryptographic software engineering. Ordinarily, development of cryptographic software is a huge challenge: security and trust is mission critical and modern applications processing sensitive data typically require the deployment of sophisticated cryptographic techniques. The proposed toolbox will allow non-experts to develop high-level cryptographic applications and business models by means of cryptography-aware high-level programming languages and compilers. The description of such applications in this way will allow automatic analysis and transformation of cryptographic software to detect security critical implementation failures, e.g., software and hardware based side-channel attacks, when realizing low level cryptographic primitives and protocols. Ultimately, the end result will be better quality, more robust software at much lower cost; this provides both a clear economic benefit to the European industry in the short term, and positions it better in dealing with any future roadblocks to ICT development in the longer term.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Showing acts results' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Main Objective The main objective of SHOW is to organise the promotion and dissemination of ACTS results to a large scale non-technical audience, by producing high quality audio-visual programmes and documentary reference information, to be diffused both as broadcast TV programs, through the Internet World Wide Web, at major international events, and through a variety of channels. The project will focus on presenting the key messages emerging from ACTS work in an attractive way for a mass market audience, in order to stimulate awareness of the attractiveness of advanced communications applications and services, and to improve the understanding of their competitiveness, employment and sustainability benefits. The project consortium includes participants from the main ACTS Horizontal Projects (in order to leverage their know-how of the Programme), well-known European TV production companies, and a Panel of Broadcast Advisors from main European Broadcasters providing support and advice. More specifically, the project aims at: 1. Providing the basic content for audio-visual production, by selecting and consolidating ACTS results. This includes defining the key messages to be communicated, producing a list (periodically updated) of draft scripts/story ideas based on the achievements and success stories of ACTS projects on which to build the videos, producing supporting documentation for the videos. 2. Producing high quality audio-visual material structured in the following way: a. 10 to 15 thematic videos of duration between 5 to 10 minutes; b. a longer duration video (approximately 25 minutes) assembled from the shorter videos; c. an audio-visual database from which producers/ journalists can extract images/video-clips to use in their media. 3. To implement an effective dis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Light-controlled bright and stable plexcitonic quantum emitters operating in both single-photon and entangled-photon-pair emission modes' (QESPEM).

assistant: **Innovation**

The emerging field of quantum information offers significant opportunities in quantum key distribution, quantum simulation and computation, metrology, and imaging. However, these applications require the use of quantum emitters that can generate single photons and pairs of entangled photons on demand. Perovskite quantum dots (PQDs), which can produce a highly coherent single-photon emission, are very promising as quantum emitters with a high single-photon purity, indistinguishability, and brightness. A unique property of PQDs is that, in contrast to many other emitters, biexciton states can be effectively generated in PQD. Two-photon photoluminescence (PL) resulting from biexciton recombination is one of effective ways of generating entangled photon pairs. However, the use of the full potential of PQDs as quantum emitters is hindered by the limitations associated with the instability of the PL signal and the low biexciton PL quantum yield.  Nanoscale plasmon–exciton interaction can significantly stabilize and improve the PL properties of PQDs due to the appearance of hybrid plasmon–exciton (plexciton) states serving as quantum emitters, thus overcoming the aforementioned limitations of PQDs. The main goal of the present QESPEM project is to design highly efficient plexcitonic quantum emitters operating as on-demand sources of pure single indistinguishable photons and pairs of entangled photons. To achieve this goal, the following objectives will be fulfilled: (1) to design quantum emitters based on the PQDs and plasmon nanostructures with implemented synergistic combination of plasmon-induces effects; (2) to develop new approaches and methods to control different regimes of plasmon–exciton interaction in the designed structures; (3) to optimize the conditions of light–m