RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Identification, homing and monitoring of therapeutic cells for regenerative medicine – Identify, Enrich, Accelerate', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Regenerative medicine focuses on repairing or replacing tissue or organ function lost due to damage or congenital defects using appropriate cells for therapy that have healing capacities like stem cells or progenitor cells. Although regenerative medicine has the potential for more effective therapeutic interventions major improvement in three areas are still needed for a wider establishment of such new concepts in clinical practise: identification of the appropriate cells with healing capacity for the use in therapy, homing of these cells to the damaged tissue, and monitoring of the therapeutic intervention and effect.  Thus, a multidisciplinary consortium has set up IDEA, a 60 month collaborative project to develop and establish:•  Photonic methods that allow a contact and marker-free identification and selection of cells with healing capacity for vascular, musculoskeletal and neuronal tissue defects;•  Magnetic cell select devices that capture and transport cells with healing potential through the circulatory system to damaged tissue and organs improving homing;•  Tracer and imaging technologies to monitor the therapeutic effects of interventional regenerative medicine by showing anatomic structure AND demonstrating cellular function using magnetic resonance imaging (MRI) and a new imaging technology known as magnetic particle imaging (MPI).The IDEA project is intended to provide collaboration between scientists and clinicians from Karolinska Institute (Stockholm, Sweden), Kings College (London, UK), Paracelsus Medical University (Salzburg, Austria) and Julius-Maximilians-University (Würzburg, Germany) together with experts from SMEs specialized in photonic technologies for tissue engineering, medical device manufacturing with extensive experience in regulatory approv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Hybrid Knowledge Society'.

assistant: **Innovation**

Hybrid Knowledge Society (HYB-KNOW) is a two-year postdoctoral project situated at the intersection of philosophy, history, and cultural studies. The projects overarching purpose is to overhaul the concept of the knowledge society in light of pressing contemporary concerns, such as the existential risks associated with the Anthropocene and the hybrid demands of the 21st-century knowledge ecosystem.The knowledge society was supposed to have initiated a technology-driven, science-based, and expert-governed way of life, but recent developments indicate that massive technology corporations exert significant influence over the public sphere, scientific institutions are challenged by resurgent extremisms, and expert knowledge is devalued in favor of conspiracy discourse. Moreover, researchers have shown that anthropogenic activity has a significantly negative impact on the Earth system, with potentially devastating consequences for long-term human survival.In these highly complex circumstances, the development of effective solutions will largely depend on the integration of the diverse, multiple elements that comprise the global knowledge ecosystem. Therefore, by drawing on the methodology of political-historical epistemology to design an innovative research framework that combines conceptual research with historical case studies, I will construct the concept of the hybrid knowledge society geared to integrate a wide range of disciplines and actors while avoiding the twin risks of neopositivism and postmodern relativism.The HYB-KNOW project will open up new research avenues, address multiple existing research gaps, and generate change-oriented knowledge to facilitate inclusive knowledge-making practices. In addition, HYB-KNOW will provide me with an opportunity to boost my re
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Novel drug delivery system produced by centrifugal technologies – composed to minimize adverse immune reactions and designed for optimised therapeutic effects'.

assistant: **Concept**

Drug delivery systems are a matter of intensive scientific investigation and technological developments. They are necessary since many active pharmaceutical ingredients to be employed in therapy, diagnostics or vaccination cause serious side effects when distributed non-specifically. Without a drug delivery system, the active pharmaceutical ingredients may accumulate in healthy and sensitive tissue, provoke adverse immune reactions, have poor solubility, low bioavailability and inefficient targeting.To meet these challenges, the key objectives of the proposed project are the development and testing of an innovative production technology for nanocapsules as a drug delivery system using centrifugation, colloidal and fluid mechanical techniques. These novel nanocapsules should be especially suited for proteins and other sensitive biomolecules which are vulnerable to degradation by existing encapsulation technologies. An immune protection consisting of a suitable polymer cover of the nanocapsules has to be developed to enable long circulation in human blood without provoking innate immune reactions by the complement, the coagulation and the phagocytic systems. Other than established polymer protection systems, the novel polymer protection should not be immunogenic to avoid accelerated blood clearance upon repeated administration. The nanocapsules have to prove to be sufficiently stable in human blood ex vivo. In vitro and in vivo tests in cancer models will be performed to compare drug efficiency, immune reactions and organ distribution of encapsulated and non encapsulated active pharmaceutical ingredients. Multidisciplinary research and innovation for nanomedicine is aimed for by collaboration in an intersectoral research team comprising mechanical and process engineering,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Proactive biobased cheese packaging'.

assistant: **Concept**

BIOPACK is a new concept in food packaging. This will involve new approaches to these of oxygen scavengers, preservatives encapsulated in cyclodextrins (CDs) incorporated into PLA (polylactic acid) and PHB (poly 3-hydroxybutyrate) as active protective agents in this bio based system. In the first instance, this new proactive packaging will be targeted at the problem of considerably improving quality and safety of cheeses. The objective is to extend the shelf life of cheeses from 2-3 months up to 9 month. BIOPACK will aim to be cost-competitive and successful concept could help to expand the market for hard and very hard cheeses considerably, especially through providing a new packaging, which makes increased exports from Europe possible. This could be of major economic benefit to cheese producers directly and farmers indirectly in many regions of Europe. The BIOPACKprinciples will also be exploitable for the packaging of other foods.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'The design of active packaging for food applications with oxygen scavenging or antioxidant capacity' (ANTIOXIPACK).

assistant: **Innovation**

This project wants to propose innovative Active Food Packaging, with oxygen scavenger or antioxidant capacity. Active Packaging has increased strongly during recent years and innovative modified atmosphere packaging (MAP) or other active packaging systems are being developed around the world. These new packaging concepts will be easily commercialized in Europe after being recently included in the European Directive for food contacting materials. The best known and most widely used active packaging technologies for food today are those engineered to scavenge oxygen. In this case, active compounds can be either contained in individual sachets put into the package or included within the plastic packaging materials. The main goal is to reduce the oxygen level which is responsible for oxidation of food constituents. Other possibilities to overcome oxidation is the use of antioxidant substances which instead of reducing the oxygen concentration, limit the presence of radicals and catalyst metals to promote competing catalysed oxidative reactions. The overall aim of this project is to develop packaging materials which actively decrease the food oxidation. This objective includes the development and the characterization of films with oxygen scavenging capacity and the inclusion of antioxidant compounds in the packaging system. The latter task will be attempted by addition of the agent in biopolymeric matrices which alternatively could be used as self supported film or as coating on other packaging materials or the product (if the coating is edible). The efficiency and potential use of these films will be studied in the case of meat and meat product storage as meat represents one of the most consumed food product across the EU whose quality is strongly sensitive to oxidation pro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Pushing back the MARGINS: investigating the PPNC-Late Neolithic conquest of near-eastern arid lands through settlement pattern analyses and landscape studies' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

At the end of the Near Eastern neolithization process (PPNC-Late Neolithic, 7th-6th millennium), a wide conquest of arid margins occurred while large villages collapsed in the Fertile Crescent. Early hypotheses posited that population movements reflected demographic pressure and took place from the western greener valleys to eastern steppes. Despite a nowadays agreement on more dynamic processes of multi-directional cultural interchanges, the complexity of this wide phenomenon remains to be understood. To achieve this goal and thanks to an integrative approach, MARGINS aims to propose renewed scenarios of ‘conquest’ and to clarify its factors of influence, in particular the respective impacts of environmental components and socio-economic choices. To do so, the project will investigate settlement patterns and land use through subsistence activities and their adaptations to constraints of arid contexts. As an impetus for the project, I question in particular the role of the pastoral nomadism, later considered as a marginal way of life, as a central driving force for this sustainable occupation of arid lands, and the status of the Syrian steppes as a cradle for the conquest towards the south, in Jordan. The project will rely for the first time for the period and region under study on a multi-scalar and diachronic approach of socio-economic mechanisms implemented thanks to quantitative and spatial analyses with the help of statistics, GIS and remote sensing technics. MARGINS will break through barriers that have prevented a “big picture approach” of the Neolithic ‘conquest’ of near eastern arid lands by bringing together an unprecedented combination of methods, interdisciplinary specialists and renown international institutions – the CNRS research unit CEPAM in France and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Open Source Software Reuse Service for SMEs' under Seventh Framework.

assistant: **Concept**

The proposed project aims to develop a set of methodologies, associated tools, and business models centred on SME Associations, which will enable software SMEs to effectively introduce Open Source Software Reuse practises in their production processes. In this scope, software reuse is regarded as the sharing of software modules across different development teams, organisations, and diverse application domains. The potential benefits from the adoption of Software Reuse practises by software SMEs could provide substantial competitive advantages against large players by improving productivity, increasing competitiveness (offer more competitive prices), and facilitating entrance to new markets. The main reasons prohibiting the adoption of Software Reuse solutions by software SMEs are the following: (1) The large initial investments in technology know-how and tools required for a successful software reuse program are inhibiting reuse for SMEs, since their budget is limited. (2) Effective accumulation of modules requires multiple products in different application domains. Software development SMEs typically develop only a limited number of products or just a single system that evolves in different versions. (3) The market presently lacks services that would allow the effective identification, cataloguing, reshaping and utilisation of open source software components. This significantly prohibits the reuse of code concerning application functionality, which is common to a limited set of domains. The OPEN-SME project aims to provide a viable solution to the aforementioned SME problems, by developing appropriate methodologies and tools, and defining adequate business models that will allow SME Associations to effectively provide Open Source Software Reuse services to their member
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Characterization of the localisation and function of cell-cycle regulators using gfp'.

assistant: **Concept**

Research objectives and content This proposal concerns the regulation of mitosis. The activity of the mitotic kinase cdc2 is tightly controlled by different regulatory proteins. An important aspect is where these factors are in the cell. Cyclins, cdks and cdc25s all comprise multigene families where one major difference between the family members is their subcellular localization. We are using Green Fluorescent Protein (GFP) as a marker to follow the localization of cell cycle proteins in living cells. We have made chimeras of GFP and different cell cycle regulators. Single cells expressing the chimeras are being followed through the cell cycle by time-lapse video-microscopy. Using this technique, I wish to investigate further the activation of cdc2 by cyclin B 1 binding and cdc25 phophatase activity. This also involves the use of mutants that are deficient in localization and/or function. Training content (objective, benefit and expected impact) In Jonathon Pines' laboratory, advanced new technology is used to study protein dynamics in living cells. I would like to become familiar with these techniques i.e. fluorescence-video microscopy, confocal microscopy and image processing. I will also use microinjection, in vitro mutagenesis and antisense technology. These methods, together with the use of GFP as fluorescent marker has numerous applications in cell biology and will potentially be very useful in my future career.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Explainable AI-Empowered Post-Disaster Network Outage Detection and Recovery in O-RAN-Enabled 6G Networks' (X-AIDRON-6G) targeting Horizon Europe.

assistant: **Abstract**

The X-AIDRON-6G project aims to develop an innovative, autonomous framework for outage detection and network recovery in disaster-affected areas using a combination of Non-Terrestrial Networks (NTNs), Open Radio Access Network (O-RAN) architecture, Terahertz (THz) communications, and advanced 6G technologies. The primary goal is to ensure resilient communication systems by leveraging NTNs, including satellites and unmanned aerial vehicles (UAVs), which will complement cellular networks in the event of network failure. X-AIDRON-6G’s approach involves the integration of NTNs with cellular networks through O-RAN architecture, allowing for seamless interoperability. This integration will enable rapid detection of network outages and dynamic recovery, ensuring connectivity in disaster scenarios. Additionally, the project will utilize explainable artificial intelligence (XAI) and machine learning (ML) algorithms to detect outages in an explainable and reliable manner. Data collected from O-RAN interfaces and packet core will be used to train these AI models, enabling rapid response to network disruptions. Upon detection of a network outage, X-AIDRON-6G will optimally deploy UAVs and utilize existing satellites to restore connectivity. These UAVs will act as temporary access points, while satellites provide high-speed and capacity midhaul/backhaul to the ground stations through THz links. The combination of AI-driven outage detection and THz-enabled NTNs will ensure fast, scalable, and cost-effective network recovery. Moreover, zero-touch network automation vision of X-AIDRON-6G will enable rapid recovery in dynamic network conditions. X-AIDRON-6G is highly relevant to the objectives of 6G, contributing to more resilient, autonomous, and sustainable networks. X-AIDRON-6G’s out
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Instability of superfluid flow in dilute Bose-Einstein condensates' (2002-2006) targeting Sixth Framework.

assistant: **Abstract**

We propose to investigate the instability of superfluid flow in a dilute Bose-Einstein condensate with repulsive interactions. Landau proposed that the primary mechanism for superfluid flow instability is the excitation of quasiparticles.While this is t he traditionally accepted explanation, the critical velocity, i.e. the velocity at which the superfluid flow becomes unstable, that Landau predicted based on quasiparticle excitation is generally known to be significantly higher than the experimentally ascertained critical velocity. Preliminary calculations show that using the breakdown of thermodynamic equilibrium as the primary mechanism for instability leads to a theorized critical velocity that is much lower than the Landau critical velocity.We thus plan to tackle the problem of superfluid flow instability by developing a kinetic theory consistent with the new critical velocity arising from the breakdown of the thermodynamic equilibrium, using this kinetic theory to develop a new two-fluid model, numerically simulating this model, and working closely with experimenters to verify our results.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Moteur thermique hybride suralimenté' (1998-2002) under Fifth Framework.

assistant: **Objectives**

L'objectif est de préparer une proposition RDT CRAFT qui permettra de développer un moteur hybride suralimenté (MOTHYS) innovant qui aura pour application le générateur électrique à haute puissance massique et a faible consommation pour l'entraînement de petits engins autonomes qui utilisent actuellement l'énergie thermique (moteur essence ou diesel) ou électrique. L'originalité de ce nouveau concept consiste à disposer dans le même compartiment tout les éléments constitutifs du MOTHYS, à savoir: un moteur thermique (de cycle 2 Temps à pistons opposés intégrant l'injection directe HPI) couplé à 2 alternateurs à haute vitesse, un moteur électrique à aimants permanents, des batteries tampons spécifiques. Le travail consite à adapter ces éléments, qui fonctionnent bien lorsqu'ils sont considérés séparément, au concept MOTHYS qui devra être une alternative aux générateurs existants de faible puissance massique.