RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Shaping Interdisciplinary Practices in Europe' (SHAPE-ID).

assistant: **Innovation**

A multitude of existing reports and assessments of AHSS (Arts, Humanities and Social Science) integration have made recommendations as to how best to encourage interdisciplinarity. However despite the existence of these reports much of their individual advice and recommendations have not been fully taken up.It is the overall aim of this project to provide concrete guidance and practical recommendations (in the form of a toolkit) for shaping future action, moving beyond expressions of intent or encouragement and into a framework for efficiently achieving the best value from activities in the interdisciplinary space. These recommendations will cover aspects such as the structure of IDR practices at the level of a research institution, the role of networks and consortia at an international level and the enabling structures such as programmes operated by research funders including national, pan-European and private research foundations. The toolkit will be an aid to the stakeholder groups being targeted by this project in achieving successful pathways to integration. These stakeholders have been grouped under 4 broad headings:1.European Research Area (ERA) -Policy Makers and Funders (both national research funding agencies but also non governmental funders such as the Wellcome Trust, Leverhulme Foundation, the The Andrew W. Mellon Foundation)2.Researchers (from across the AHSS and STEM disciplines both those engaging in IDR projects and those working in monodisciplinary cultures)3.Research Performing Organisations (i.e. Universities, Academies of Sciences, Enterprise)4.Research Users (Enterprise, Civil Society, the cultural sector and the citizen) The project will enable comparisons of IDR practices and results with reference to enhancing approaches to scholarship and to el
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'HARD TO ABATE INDUSTRIES REPOWEREURING DIGITAL & DEEP-TECH STARTUPS TO SCALE IN EUROPE THROUGH CROSS-BORDER ACCELERATION IN LEADING ECOSYSTEMS' (HARD2SCALE) targeting Horizon Europe.

assistant: **Abstract**

HARD2SCALE aims to initiate a cross-fertilization process as the foundation of a cross border accelerator leveraging the  disruptive potential of digital and deep-tech solutions from promising startups to enable green transformation pathways for Energy Intensive and Hard to Abate Industries (EEIs and HtA). HARD2SCALE is a joint effort of 8 expert organizations (4 from emerging/moderate ecosystems and 4 counterparts from leading/strong innovator ones) offering a complete set of services as a gateway to funding and markets. The HARD2SCALE cross border accelerator integrates the specific needs and challenges of emerging EU ecosystems by engaging local quadruple helix stakeholders in a consultation and co-design process leading to long-term, mutually beneficial collaborations. Building on the expertise, assets and networks of the consortium partners (including the EIC Community & BAS and Startup Europe), the HARD2SCALE support services aim to holistically enable startups align their technology development and IPR roadmap with the market deployment and funding needs. By drawing inspiration from the growth journeys of “hyperscalers” (startups with significant fundraising or commercial achievements in a short time period) from the consortium partners’ portfolios, the HARD2SCALE accelerator aims to enhance the investor and market readiness of 40 digital and deep-tech startups targeting 4 EEIs and HtA sectors before introducing them to relevant contacts. HARD2SCALE offers the 40 startups the possibility to join 2 leading ecosystems – Finland and France – where they will be introduced to relevant corporate business partners and investors. HARD2SCALE initiates an open innovation process where the connection between emerging and leading ecosystems will bring forward collaboration o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Efficient Stable Multilevel Ferroelectric Tunnel Junctions Enabled by Layered 2D van der Waals Heterostructures' (ESTRELLA).

assistant: **Concept**

Through ESTRELLA I aim to develop energy efficient (i.e. field-driven), stable (retention time > 10 years), multilevel (16 state/4-bit) two-terminal devices based on 2D ferroelectric CuInP2S6 (CIPS).  The project will provide a comprehensive investigation of CIPS material properties both as an exfoliated film and when integrated in ferroelectric tunnel junction (FTJ) devices through multilayer vdW epitaxy. The final devices aim to exploit the atomically sharp interfaces of vdW heterostructures, small domain wall energy and slow but stable switching of CIPS in order to produce a ferroelectric memory suitable for neuromorphic applications. Furthermore, I will investigate the impact of different electrodes on tunnelling electroresistance (TER) and switching voltages in order to design an optimal CIPS-based FTJ. This draws together my experience in the fields of ferroelectric devices and materials characterisation with that of the supervisor (Prof. Luis Hueso, CIC nanoGUNE), who is an expert on 2D materials and van der Waals (vdW) heterointegration. ESTRELLA will target areas of materials science - heterointegration techniques, 2D film characterisation; physics - understanding of domain dynamics and 2D material interfacial interactions; and electrical engineering - targeting FTJ devices as building blocks for neuromorphic computing. Parallel to my scientific work, with ESTRELLA I will develop skills as an independent researcher through publication and dissemination of my work, supervision, collaboration and project organisation.


**Keywords:** ferroelectrics, 2D materials, van der Waals heterostructures, neuromorphic, nanodevices
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Strategic Risk Assessment and Contingency Planning in Interconnected Transport Networks' (STAR-TRANS).

assistant: **Concept**

STAR-TRANS aspires to develop a holistic risk assessment methodology for Critical Infrastructure and apply it to a wide panel of international transportation infrastructures to analyse and assess common issues for risks, threats and vulnerabilities and identify possible interdependencies assessing the impact of failures on interconnected transportation infrastructures. The successful project outcome will offer important aids for decision-makers to determine priorities among multiple contingency alternatives by evaluating the consequences (cost, timing, resources, etc) of proposed actions. The improvement of the response and management capabilities regarding assessment of incidences / failures in critical transport infrastructures will be achieved through the identification and closure of relevant knowledge gaps and through the development, validation and usage of computational modelling tools. STAR-TRANS aims at developing a modelling formalism in which specification of the structure and associated assets of European transportation networks as well as the specification of the dependency types between the assets of interconnected and interdependent transportation networks is facilitated. This modelling formalism will consider a transportation ‘network of networks’ as consisting of nodes and links. In so doing, tools from network and graph theory and the systems area will be employed. A specialised software system will be developed that will support the end users, and network operators needs. The software tool will provide the technology to link together any relevant assets of interconnected and interdependent transport networks, such that risk managers, policy makers and others can, subsequently, be provided with the impact that a risk incident on an asset of a specific
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Joining ecophysiological Understanding and global ecosystem modelling for improved simulation of Land surface Interactions with the Atmosphere'.

assistant: **Innovation**

A thorough understanding of feedbacks between the terrestrial biosphere and the climate system is pivotal for any climate change mitigation strategy. Such feedbacks could significantly affect and potentially accelerate climate change. Terrestrial biosphere models are increasingly coupled interactively to ocean and atmosphere models with the goal to quantify these feedbacks. However, state-of-the-art terrestrial biosphere models fall short of the current understanding of important ecophysiological controls of land surface processes, as evidenced by the increasing amount of ecosystem observations that have become available recently. This project aims at bridging the gap between observational science and large scale biosphere modelling by developing representations of relevant ecophysiological processes at a level of detail suitable for an Earth system model. Two of the most important fields that urgently need to be better represented will be addressed, namely the biological control of canopy conductance and plant-soil interactions. Both substantially influence land surface fluxes, ecosystem productivity and long-term carbon sequestration. The project will use innovative techniques to develop novel process representations of canopy conductance by combining different types of ecosystem observations such as eddy-covariance based flux observations and plant trait data collected by the IGBP fast track initiative on plant functional types. Novel representations of soil organic matter dynamics, including a substrate control, and plant nutrient uptake pathways will be developed and evaluated based on recent laboratory and ecosystem manipulation experiments. The improved model will be used to revise predictions of state-of-the-art terrestrial biosphere models for present-day and f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Proneural mechanisms coupling cell cycle exit and differentiation', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Understanding how a neuron develops is one the most challenging enterprises of modern biology, with obvious impacts in developmental biology and biomedicine. Proneural factors regulate many of the steps involved in the generation of new neurons and their functions have been thoroughly characterised at the cellular level. However, little is known of the mechanisms they use to evoke such diverse effects throughout neurogenesis. Therefore, the characterisation of molecular pathways activated by a proneural protein will be particularly instructive to cast light on the multistep process driving progenitor cells into assorted neuronal fates. My main goal will be to examine the implication of the bHLH proneural proteins in coupling cell cycle exit and differentiation within the developing mouse telencephalon and in cultured neural stem cells. To this aim four recently identified Mash1 targets, presumably involved in cell cycle control, will be functionally approached by electroporating overexpression constructs or small interfering RNAs in the neural stem cell line NS5. Subsequently, various parameters of neurogenesis will be analysed, with special emphasis in cell cycle arrest and neuronal differentiation. The results will be contrasted in vivo by in utero and/or ex vivo electroporation of mouse embryonic brains. Both dorsal (Mash1+/Ngn2-) and ventral (Mash1-/Ngn2+) telencephalon will be targeted to analyse Mash1 and Ngn2 control over the four genes, which are naturally expressed in both domains. Overall, this project seeks to fill the gap that presently exists between the cellular effects evoked by proneural proteins and the mechanisms they use to shape the complex vertebrate nervous system, giving insights into effective methodologies to manipulate neural stem cells for the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Physical modelling of stellar activity effects to discover and measure exoearths' in the context of a Horizon Europe call.

assistant: **Objectives**

Exoplanet research has experienced enormous growth and is now pushing instrumental limits to find temperate terrestrial planets and precisely characterise their atmospheres. Extreme-precision radial velocity (RV) instruments (e.g. ESPRESSO), offering 10 cm/s stability, and space telescopes (e.g. JWST, Ariel), attaining relative flux uncertainties of 10 ppm are becoming a reality. But there is a shadow of concern hovering over such fantastic performances. The intrinsic variability of the stellar hosts can overwhelm the instrument error to become the dominant uncertainty. Recent results with ESPRESSO and JWST data provide vivid illustrations of the daunting effects of such limiting factor. An ambitious, ground-breaking, and comprehensive effort to model and correct out stellar activity effects shall therefore be undertaken. Our pioneering results show that the unique combination of a physical model and contemporaneous multi-technique monitoring can disentangle the effects of stellar activity from RV time-series and transit spectroscopy. The SPOTLESS project will implement this methodology by building a realistic stellar activity simulator and develop correction strategies using, e.g., machine learning algorithms and direct inversion. This is more reliable than purely data-driven methods, which often suffer from overfitting due to the lack of a physical context. Four main objectives will be pursued: 1) A physical model of the active solar surface to explain Sun-as-a-star observables, 2) Generalise to other spectral types & parameters, 3) Physically-motivated RV activity corrections at 10 cm/s, and 4) Physically-motivated transit activity corrections at 10 ppm. From available and future observations, SPOTLESS will deliver new challenging exoplanet RV discoveries and unbiase
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Bio-Stabilized Multiphase Materials as Carriers for Biopesticides' (BIOMAC-BP) targeting Horizon Europe.

assistant: **Abstract**

Current agricultural pest control is highly dependent on synthetic pesticides. These pose significant risks to the environment and human health. Microbial pesticides offer promising alternatives with greater specificity and reduced risk. However, their use is often hampered by ineffective formulations containing synthetic additives which pose an environment risk themselves. We propose to solve both problems by developing formulations that use only bio-sourced materials to stabilize the interface between two fluid media. The 2-Phase High Interface Materials (BIO2PHIMs) that form in this manner are ideal carries for a bacterial cargo, and have superior stability and application features as formulations.The project’s main objectives are fourfold: (i) Improve bacterial fitness in biopesticide formulations using BIO2PHIMs as carriers. These materials not only resist destabilization, but also allow for the inclusion of nutrient-supplying mediums. (ii) Enable rational formulation design by developing models with predictive capabilities for the correlations between the physicochemical properties of BIO2PHIM, the viability of enclosed bacteria, and their post-deposition performance. (iii) enhancing the benefits of BIO2PHIM by identifying bacteria with high pesticide potential, improving application methods and monitoring the environmental impact of the formulations. (iv) Training a cohort of young scientist equipped with the necessary interdisciplinary knowledge to tackle the synthetic pesticide emission problem, and implement solutions.To achieve these goals, we will implement a truly multidisciplinary approach, bringing together expertise from microbiology, soft matter physics, physical chemistry, chemical and materials engineering and agricultural science.Realizing BIO2PHIM p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Paragon Novel Vaccine (PNV) an effective protection against all serotypes of five deadly bacteria to eradicate Antimicrobial Resistance (AMR)' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Immunethep has developed, patented (WO/2015/189422), and successfully undergone preclinical trials for a new breakthrough vaccine (PNV-Paragon Novel Vaccine). It protects against bacterial infections caused by 5 different bacteria: S. aureus, S. pneumoniae, K. pneumoniae, E. coli and GBS. Our innovation relies on the discovery of a virulence and immunosuppressive mechanism common to these pathogens. The bacteria excrete a highly immunosuppressive protein designated as glyceraldehyde-3-phosphate dehydrogenase (GAPDH), which disables the host immune response to infection. PNV works by blocking bacterial GAPDH, while not reacting to human GAPDH, allowing the host immune system to fight infection and eliminate the bacteria. Preclinical trials demonstrated high levels of efficacy against any of the 5 bacteria with an excellent safety profile. PNV is the world’s first vaccine not only to prevent multiple bacterial infections but for all invasive serotypes, including multi-resistant strains.


**Keywords:** Multivalent vaccine for five bacteria (1st worldwide),Preventive immunotherapy for infectious diseases,Antimicrobial Resistance (AMR),Effective against all serotypes (full coverage) ,GAPDH immunosuppressive protein
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Degradation of Biomaterials' in the context of a Fifth Framework call.

assistant: **Objectives**

We are proposing to launch a series of two meetings on the subject of the Degradation of Biomaterials. At this stage only funding for the first meeting is being requested. However, reference is made to the second event in order to provide assessors with an overview of the project. The objectives of the proposed events are to determine, assess and understand by multi- and inter-disciplinary collaboration the processes of degradation of medical devices. Released degradation products and their metabolites are the most important reasons of biological reactions and health hazards. On the other hand, this behaviour can positively be exploited by the development of specific materials to be replaced by normal soft or hard tissue during a specific degradation period and/or to release during this period active components, such as active molecules, enzymes, biotica or growth factors. The assessments and understanding of the accidental or wanted degradation processes are necessary to improve by physical, chemical alld biological technology existing materials to prevent accidental degradation and to develop new materials with activating compounds and tailored for drug delivery. Single-component medical devices become less frequent, contact between different materials is mostly unavoidable and there is a significant increase of the use of multi-material and composite devices with improved biofunctionality.The relation between the individual events is subsequently respected by the need of multi-and interdisciplinary co-operation and the requirement of multiple material families. In this way, the proposed series will have an evolutive character starting from basic materials and evolving via modern but nevertheless still problematic materials such as ceramics and polymers and their comb