RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Mechanisms of Microglia Synapse Communication' (MicroSynCom) targeting Horizon 2020.

assistant: **Abstract**

Microglia are the resident tissue macrophages of the brain and represent cells of the innate immune system. Looking at microglia from the immunological perspective, much is known about their role during inflammatory processes, factors that activate them and how they response e.g by releasing cytokines to mount an inflammatory response. This response has been shown to be detrimental during disease processes and lead to pruning/loss of synapses, a task microglia carry out also during development. Although microglia obviously play an important role in synaptic pruning and loss, it remains an open question, whether microglia are involved in the process of synapse formation under physiologic conditions. Therefore, the main hypothesis of MicroSynCom is that microglia represent the mediator of synapse formation or linker between pre- and post-synapse: sensing neurotransmitter release at highly active pre-synaptic sites and actively orchestrating the formation of new spines from the dendrite. I propose to investigate and reveal the underlying mechanisms of this tripartite microglia synapse communication process. Therefore, we will use two-photon stimulated emission depletion microscopy (2P-STED), novel viral and genetically encoded sensors for neurotransmitters, as well as optogenetic and chemogenetic manipulation tools. These methods will be combined with behavior test in freely moving, but also head-fixed mice to visualize microglia mediated synapse formation in awake mice. This will allow us for the first time to visualize, investigate and reveal the mechanisms establishing this novel role of microglia as the mediator of synapse formation in life animals and relate it to physiologically relevant neuronal network rewiring.


**Keywords:** microglia, synapse formation, dendrit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Pan-European Photonics Task Force: Integrating Europe's Expertise on Photonic Subsystems'.

assistant: **Innovation**

EURO-FOS aims at creating a powerful pan-European network on photonic subsystems by clustering top European systems groups with proven track record in the design, development and evaluation of photonic subsystems. EURO-FOS aims at bridging the gap between research on device-level physics and new architectures from the network-level. The first objective of the project is the integration of researchers through exchange and mobility, allowing for innovation and reinforcing common research thrusts. The second objective is the access to expensive infrastructure creating economies of scale in the development and testing of photonic subsystems. The third objective is the strengthening of European research by creating a mechanism for partners to access devices developed in complementary European projects on photonic components. Functional integration of devices will create new ideas through the design and development of new subsystems within the project. EURO-FOS fourth objective is to complement European Commission efforts for combating Europes difficulty to turn scientific know-how developed in universities into exploitable technology. This will be achieved through the creation of an academic pan-European laboratory with strong industrial links. The creation of this lab can bridge the gap created by the shutdown or downsizing of major R&D industrial labs and help innovative SMEs that find it increasingly difficult to allocate R&D expenditure for basic research and expensive testing facilities. EURO-FOS is expected to have a high impact on Europes research through integration of people and clustering of research groups under the guidance of European industry. The creation of a unified and coherent European network of researchers with excellence in this field will ensure th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Metal Complexes for Hydrogen Activation' in the context of a Sixth Framework call.

assistant: **Objectives**

Hui-Fang Zhu is a multi-award-winning scientist of enormous promise and potential. She has an excellent record of achievement in coordination chemistry, and her work is certainly of the highest international quality. She now wishes to build upon and apply her impressive array of scientific skills to an ambitious and innovative project to develop new ecomaterials as catalysts for the binding and activation of hydrogen using designed metal thiolate complexes that will mimic hydrogenase enzymes that activate hydrogen in vivo. The Fellowship will give invaluable research training and knowledge transfer, and will afford further collaborations with industry and other research groups in the UK and Germany. The scientific and technological imperative for this research is derived from the urgent societal, environmental and economic need to develop new methodologies and technologies to control the use of hydrogen as a clean and efficient fuel, and to understand the molecular and red-ox chemistry taking place at hydrogenase bio-sites, which are highly efficient biocatalysts for hydrogen activation. The work programme meets the priorities under the FP6 Call on Knowledge-based Multifunctional Materials, NMP-2002-3.4.2.3-1 and on Sustainable Development, SUSTDEV-1.2.2. State-of-the-art facilities at Nottingham will underpin the Fellowship both scientifically and intellectually in a stimulating and multi-disciplinary environment (Marie Curie Host Fellowship Centre COSMIC MCFH-2001-00448). The Fellowship will also exploit the wider University of Nottingham Career Development programme and the Royal Society of Chemistry 1-year formal assessment programme, which provide a range of invaluable managerial and leadership skills for young scientists. The potential impact of the project is ver
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Production of hydrogen and methane during the anaerobic bio-treatment of olive pulp' (1998-2002).

assistant: **Concept**

This is an assessment of the work performed by Hariklia Gavala in my group at the Technical University of Denmark. Her work concerns biodegradation studies of pollutants in waste material such as sewage sludge and has been done over the last one and a half year. During this period Hariklia Gavala has proven herself to be a hard working scientist who works devoted on achieving her goals. She has recently obtained a number of new results and is currently working on several publications. I can therefore recommend that her for a continuation of her fellowship.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Osteoarchaeology of the Dutch Middenbeemster Post-Medieval Cemetery: Lifeways of a Colonizing Farming Community during the Little Ice Age'.

assistant: **Objectives**

The Dutch town of Middenbeemster was established in the early 17th century upon land reclaimed after a series of lakes were drained. In 1623 the colonizing farming community built a church and graveyard that was used until 1868. Excavation has revealed over 400 burials of all age groups. Osteoarchaeology, the scientific study of human skeletal remains uncovered in an archaeological context, contributes a vast amount to our understandings of past peoples. A full complement of osteoarchaeological methods can answer questions about the mobility, demography, diet, activity, and health of this colonizing community – thus, reconstructing their lifeways. The osteoarchaeological analysis of Middenbeemster inhabitants will be central to examining the effects of the Little Ice Age in the Netherlands, a cold period between 1550AD to 1850AD. In Europe, the Little Ice Age caused shortened and less reliable growing seasons and increased flooding, which resulted in many years of dearth and famine. Episodes of starvation and illness are detectable via the macroscopic analysis of human skeletal remains, as are estimates of sex, age, stature, and activity-patterns, all of which will permit a refined picture of factors related to morbidity and mortality. Furthermore, chemical analyses of small tissue samples to determine diet and mobility will permit consideration of where settlers were coming from, and dietary variation related to crop selection and yield. The interpretation of results will be aided by archival materials about immigration, paleoenvironmental reconstructions, epidemiological patterns, and archaeological data about the socioeconomic status of Middenbeemster farmers. It will be particularly interesting to examine if and how these patterns changed in the over 250 years of ce
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'A novel dual fuel system for diesel locomotive modernisation to CNG or LNG operation' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Company is developing proprietary state-of-the-art dual fuel technology and has designed low-cost, scalable,  installable at minimum cost and lead time dual fuel system tailored for locomotive sector. The project will accelerate diesel locomotive market transition from oil based diesel fuel to cheaper, cleaner and much more sustainable alternative and bio fuel - methane either in form of Liquefied (LNG) or Compressed (CNG) methane. Switching the fuel enables locomotive sector to strengthen the advantage railroads hold over trucks in long-haul shipping, comply with tougher environmental and exhaust standards and decrease fuel costs in the same time.In recent years methane is getting a high attention from transport companies, investors, and government in rail sector with US leading the market development. Opportunity is being seized by GE, CAT, EMD and few smaller companies by piloting and testing their dual fuel products. EU is clearly lagging the rest of the world in the adoption of methane as the next gen fuel for locomotive applications. Being European company DiGas is bringing to market dual fuel product dedicated for locomotive sector out competing all similar products on a global scale. With today’s average cost of locomotive dual fuel retrofit  500k EUR, the proprietary game changing innovation enables multiple times decrease of locomotive retrofit costs combined with high diesel fuel substitution rate (60-80%) of the system allowing for commercially attractive payback periods (4 y for shunter and 2 y for main-lines) for rail operators.In project Phase 1 DiGas strives to investigate project risks and potential hurdles of the product commercialization kick-off in Phase 2, for example certification and homologation routes, rail rolling stock and customer for various
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Wind turbine blade aerodynamics and aeroelastics: closing knowledge gaps know-blade""' to be submitted under Fifth Framework.

assistant: **Abstract**

Objectives and problems to be solved:The objectives of the project are to fill in important knowledge gaps connected to the wind turbine blade design process and develop the necessary design tools. Traditional tools used in the wind turbine industry are unable to handle various fundamental flow problems. It is believed that one feasible path to obtain the missing knowledge is through development and application of tools based on Navier-Stokes solvers (NS solvers). The goals are to provide industry with applicable knowledge and methods based on NS solvers that will allow manufacturing of more optimal, stable and cost effective wind turbine blades. There is a strong confidence within the consortium, based upon recent verification studies that a series of unsolved aerodynamic and aero elastic problems within the wind energy community can be addressed successfully using NS solvers.Description of work:Four very important issues will be treated in the present project, with activities split in five technical work packages.The topics are the following:- Improving the power prediction capability of existing state of the art 3D Navier-Stokes solvers, by including models for the laminar/turbulent transition process, and using advanced turbulence models. Especially for stall controlled wind turbines, this will allow for a much more optimised blade design, because the power production, blade loading and the stall behaviour can be predicted more accurately.- Models for aerodynamic accessories used by wind turbine industry, as vortex generators, stall-strips, zigzag tape etc will be developed, and implemented in the existing Navier-Stokes solvers. Additionally numerical simulations of active flow control concepts, such as pulsating jets, will be carried out. This will allow wind turbi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Differential effects of dietary potassium intake on blood pressure' (HyperK).

assistant: **Concept**

As the primary risk factor for the onset of cardiovascular disease, hypertension is a major contributor to premature death and disability. High dietary sodium (Na+) consumption is often considered a primary culprit for hypertension, but evidence exists that increasing dietary potassium (K+) consumption may lower blood pressure (BP). However, a number of studies in humans indicate that higher K+ intake is not always beneficial for blood pressure  effects that the host lab recently confirmed in rodents. Reducing and maintaining a lower BP based on dietary intervention requires understanding of the long term and/or accumulated effects of the intervention and the underlying molecular basis. This project will increase our understanding of the differential effects of dietary K+ on BP, the role of the kidney and potentially the vasculature. The project objectives are to: 1) determine the optimum dietary K+ intake that reduces and sustains lower BP; 2) identify factors in the kidney that drive K+ sensitivity of BP; 3) assess if sustained high dietary K+ intake changes vascular function; 4) investigate the molecular basis of any vascular remodelling that promotes, or is consequential, to increased BP during prolonged high dietary K+ intake. To address these questions I will apply a broad range of interdisciplinary skills and methods: telemetric monitoring of BP, in vivo assessment of kidney and vascular function in animal models and gene modified mice, RNA sequencing (including single-cell) and bioinformatics, optical clearing and innovative 3D multiplex imaging of tissues. Successful completion of the research in this proposal provides an excellent opportunity to uncover new targets and strategies for the management of hypertension. From a personal perspective it represents a m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Aviation Noise Research Network and Coordination' (2007-2013).

assistant: **Innovation**

The X-NOISE EV Coordination Action, through its network structure and comprehensive workplan involving experts groups, scientific workshops, international cooperation seminars and a common information system, addresses the noise challenges faced by Aviation. To this end, it will more specifically:- Evaluate EU-funded projects results and assess their contribution to the state-of-the-art.- Formulate, through development of common strategies and complementarity with national activities, priorities and key topics for future projects aimed at noise reduction at source, low noise operations, and improved understanding and modelling of the impact of aircraft noise in the community, including environmental interdependencies.-  Ensure dissemination and exploitation of research findings, including technical information aimed at Regulatory  Bodies and Policymaking Agencies.- Contribute to an improved integration of the European Aviation Noise Research Community through a network of National Focal Points covering all countries with such technical interest- Identify potential reinforcement of future projects partnership through extended international networking and dedicated processes to foster new collaborations and promote novel ideas.The project scope is fully consistent with the FP7 Transport workprogramme (Aeronautics),  significantly contributing to the objectives of reducing Aircraft Noise by 10 dB per operation as set by the ACARE 2020 Vision,.while addressing key factors associated with Airport Noise issues.Over 4 years, the project will involve 29 partners from 21 countries (FR, UK, ES, NL, BE, DE, SE, IT, PL, HE, HU, CZ, LT, IE, PT, RO, CH, RU, UKR, EG, BR), combining the complementary skills and expertise of industry partners, SMEs, universities and research establishme
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Delivering affordable and sustainable housing in Europe' (RE-DWELL) under Horizon 2020.

assistant: **Objectives**

RE-DWELL will train a new generation of professionals with the transdisciplinary skills which are needed to address the urgent need of affordable and sustainable housing, a major challenge for European societies. To date, affordability and sustainability of housing have been addressed separately, from various disciplinary perspectives (e.g. architecture and planning, economics, sociology) and realms (e.g. policy-making, sustainable development, urban planning, green building). However, recent research indicate that it is necessary to consider the affordability and the sustainability of housing as complementary and interrelated aspects which need to be addressed with a transdisciplinary approach, by combining academic disciplines and engaging non-academic sectors in a common production of knowledge. Ten academic beneficiaries and twelve non-academic partner organisations will jointly contribute to creating a transdisciplinary research environment which encompasses the various disciplines, sectors and stakeholders involved in the provision of A&S housing. Fifteen ESRs research works will interlink three key areas underpinning affordable and sustainable housing: 1. Design, planning and building; 2. Community participation; and 3. Policy and financing. ESRs trained in this programme will be able to develop a capacity to operate across fields and sectors, to provide innovative solutions to the growing housing problem affecting our societies.


**Keywords:** sustainable housing, affordable housing, sustainable development, urban regeneration, cohousing, building energy efficiency, industrialized construction, right to the city, housing financing