RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Life of Giant Phages' (GIAPHAGE).

assistant: **Innovation**

Bacterial viruses, phages, are ubiquitous and most numerous entities in the biosphere. Development of sequencing techniques has increased our understanding on the diversity of phages that have not been isolated due to lack of cultivable hosts and/or suitable isolation methods. While sequence data enables a better view to the viral diversity, at the same time lack of functional data and biological connection increases. Recently, different studies have found megaphages (mainly phages with a genome over 600 kbp) by assembling metagenomes from various environmental samples. However, no such isolates have been obtained thus far meaning that their characteristics and host interactions are completely unknown. In this ERC project, I will enlighten the life of giant phages, the term I coined for both jumbo and megaphages. I will achieve this by using the first megaphage isolates that I have isolated from boreal freshwaters. During the project, evidence on the megaphage structure, the host interactions and symbiotic relationship with host will be provided. Using a unique set of different phage sizes infecting the same host I will determine the size correlation to different life history traits. I will provide insight to the mutualistic relationship between bacteria and their viruses and reveal new mechanisms behind phage competition. I will also determine the environmental preferences for the megaphage emergence and abundance in boreal freshwaters. In this proposal, I aim to understand How, Where and When megaphages are isolated. Consequently, results will aid in understanding the role of megaphages in other environments such as gut microbiome and potentially provide avenues for developing new genetic tools. This project will open new understanding for microbial ecology and especi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Enabler for next generation service delivery'.

assistant: **Concept**

The MULTINET communication system will be capable of providing the network and application functionalities so that multiple simultaneous networks can be seamlessly handled to optimise communications in multiple dimensions; while sustaining the existing mobile industry and attracting new business revenue. The capabilities provided facilitate mobile broadband multimedia communication services of high quality and functionality with an optimum cost, tailored to the communication offer provided.The project aims at providing the necessary networks and application functionality enhancements for seamless data communication mobility in an scenario where the user can benefit without intervention from simultaneous transparent network connectivity among the available access networks to benefit from ubiquitous access to broadband applications. The goal consists in the development and validation of an evolved communication system that provides mobility to users in the context of mobile and wireless networks (IP based networks), without modifying neither the existing network, nor the user applications, and in a transparent way.To achieve this strategic objective, a harmonized technological RTD approach is implemented by providing:- Tools and protocol for seamless broadband multimedia session delivery across heterogeneous networks.- Middleware techniques for application layer service to adapt to underlying bearer characteristics.- Mechanism for bearer services to adapt to the changing nature of multimedia applications.Two scenarios identified are capable of capturing broadband communication needs at work while on the move. They have also been selected in order to increase the impact of the technology once demonstrated: High-Tech Machinery Maintenance and Utility Companies. Large enterp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Fibre Reinforced thermoplAstics Manufacturing for stiffEned, complex, double curved Structures.' (FRAMES) under Horizon 2020.

assistant: **Objectives**

The fuselage of the next generation of Large Passenger Aircrafts´ (LPA) will be made with thermoplastic (TP) composites. In fact, even if this kind of materials are being increasingly used in aerospace industry, as they contribute to lighter aircrafts and consequently to fuel consumption reduction, there are still some issues to be overcome until this becomes a reality.The manufacturing complex forms of rear end section with continuous fibre-reinforced TP still poses a considerable challenge: higher processing temperatures and raw material costs, need of complex temperature-controlled tooling, etc. Automated fibre placement (AFP) is a workable alternative for more complicated TP Composites (TPC) shapes with varying part thickness (e.g., fuselage shells, wing and stabilizer torsion boxes and stringers), but one of the challenges is void removal, which is more difficult with TP than with thermosets. FRAMES aims to fully define technical and cost performance of an optimized integral TP rear end manufacturing process with critical design features as an alternative to thermoset materials. Thanks to a self-heated tool with process driven heating zones and advanced lay up process simulation, FRAMES will be capable of predicting heating law for efficient TP-AFP, correlated with lay-up trials, mastering TP-stiffeners manufacturing process, optimizing co-consolidation cycle. Its main innovation relies on the co-consolidation of a double curved and thick skin with its entire stiffening structure in one shot.FRAMES will support the spread of alternative heating process for thermoplastic AFP by developing a simulation tool able to predefine processing parameters of the most common aerospace grades thermoplastics. At the end, the advanced rear end (ARE) concept that will allow the sa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Thermoplastically deformable circuits for embedded randomly shaped electronics' (TERASEL).

assistant: **Concept**

The overall aim of the TERASEL project is the development, the industrial implementation and the application in a wide range of domains of large area, cost-effective, randomly shaped electronics and sensor circuit technologies. More specifically the TERASEL objectives are the following :<br/> To develop a basic technology platform for rigid large-area randomly shaped electronic circuits. Key common features of the technologies in this platform are :<br/>1. Electronic circuit fabrication and component assembly on flat substrates, compatible with existing equipment.2. Application and embedding of the flat circuits in thermoplastically deformable polymers.3. Development of high pressure, low temperature thermoforming technologies to deform the polymer embedded flat circuit into its random final functional shape.<br/> To set up a complete multi-competence industrial production chain for such circuits. Indeed, the goal is to achieve mature, near-to-production industrial processes for manufacturing randomly shaped circuits.<br/> To apply the developed technologies in a number of functional demonstrators close to products: a TV set with ambient illumination, a free-form man-machine interface, an intelligent car interior component, a 2.5D lighting device, a household appliance.<br/>This novel technology can be developed successfully only thanks to the synergy and intensive co-operation between partners of the 2 industry sectors involved in TERASEL: the electronics circuit fabrication and assembly industry on one hand, and the polymer processing industry on the other. 6 SME's and 5 large industrial partners are complemented with 4 research institutes, thus forming a well-balanced consortium, fully capable of achieving the ambitious TERASEL goals. The merging of polymer and el
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Mechanism, regulation and functions of genome folding through loop extrusion by cohesin-NIPBL' (LoopMechRegFun) targeting Horizon 2020.

assistant: **Abstract**

Since its discovery 150 years ago, DNA has been intensely studied. As a result, it is understood in some detail how genomic DNA is replicated, repaired and segregated, and entire genomes can be sequenced. However, how DNA is folded in chromosomes has remained a mystery. It has been proposed that this is achieved by a process called loop extrusion. This hypothesis proposes that SMC complexes, multi-subunit ATPases present in all kingdoms of life, reel genomic DNA into loops, thus bringing distant loci into proximity. This process is thought to have important structural and regulatory functions, such as the separation of bacterial genomes and the folding of eukaryotic DNA into loops and topologically associating domains (TADs), facilitating sister chromatid resolution, gene regulation and immunoglobulin gene recombination. We discovered recently that in vitro single molecules of the SMC complex cohesin bound to NIPBL (cohesin-NIPBL) indeed rapidly extrude DNA into loops at up to 2.1 kb/s. These results provided the first direct evidence for the hypothesis that cohesin generates chromatin loops and TADs by extrusion. However, the most fundamental questions relating to this process remain unanswered: What is the mechanism of loop extrusion? How is this process controlled? How does cohesin extrude chromatin fibers in cells, and how does this contribute to the processes mentioned above and to other functions? We are proposing to use our single-molecule loop extrusion assay and other techniques to address these questions. Answering these will be essential for understanding genome architecture and regulation, will provide insights into mechanisms of gene regulation and recombination, will reveal how SMC complexes function as molecular ‘motors’, and may provide insight into the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Innovation in germplasm cryopreservation for improved animal breeding and the conservation of Europe's livestock biodiversity'.

assistant: **Concept**

CryoStore aims to create a lasting research and education network for a new generation of animal husbandry experts with a broad, multidisciplinary approach to the complexity of modern animal production and the conservation of farm animal biodiversity, taking into account economic, societal and environmental needs. A vibrant and effective animal breeding and production industry is essential to meet Europe´s increasing need for sustainable and secure food production. Farm animal and fish breeding are global, highly competitive and knowledge intensive sectors, and currently European breeding organisations are global leaders. If Europe is to maintain its competitive advantage in these strategically important industries innovative research is needed in those reproductive technologies that underpin efficient and profitable animal production. As such, CryoStore will develop innovative technologies for improved cryopreservation of germplasm (gametes, embryos, germ cells) for use in assisted reproductive procedures, leading to increased reproductive efficiency in Europe´s livestock and aquaculture industries. Technological advances in germplasm cryopreservation will also be of key importance to future initiatives aimed at conserving Europe’s livestock biodiversity, through genetic resource banking. Conserving Europe´s numerous and diverse native breeds, many of which are seriously threatened, will be of crucial importance to future sustainable animal production as genetic biodiversity allows the expression of advantageous traits influencing adaptability to harsh environments or disease resistance. It is likely that selecting for naturally occurring traits will help overcome future difficulties in livestock production wrought by climate change. The intensive training of CryoStore
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Towards optogenetic cortical implants for hearing impaired' (HearLight).

assistant: **Concept**

Cochlear implants are the first and currently most successful sensory rehabilitation strategy, and equip thousands of hearing impaired patients. However, they suffer from strong information throughput limitations, making music perception and speech intelligibility in noise impossible, extremely detrimental to implanted patients. In this project, we propose to establish a clear proof of concept for a radically new auditory rehabilitation strategy by direct stimulation of the main sound processing center in the brain, the auditory cortex. The auditory cortex not only offers one order of magnitude more interfacing surface, to boost information throughput, but it is also a plastic structure, adaptable to complex auditory codes, which could benefit from acoustic information preprocessing by modern artificial intelligence algorithms. To demonstrate that cortical implants are feasible and outperform cochlear implants, artificial sound perceptions will be optogenetically generated via an LED display placed over the full extent of auditory cortex in behaving mice. Perceptual precision for a wide range of acoustic features will be precisely benchmarked against cochlear implant thanks to a range of psychophysical assays available in this animal model. The benefits of sound preprocessing by machine learning algorithm s(deep learning networks) will be tested, and we will develop a new generation of ultrathin, flexible, biocompatible LED displays, that could be placed on the convoluted surface of human auditory cortex to activate precise and rich perceptions. Together, these brain-interfacing and bioelectronics innovations will enable a new implant strategy in that promises to be a major changer for hearing restoration quality in deaf patients, and pave the way for improvement of oth
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Evolutionary and variational problems related to nonlinear continuum theories and solid phase transformations' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

Research objectives and content The objectives of this project are to undertake research in nonlinear evolutions equations related to elastodynamics and the analysis of microstructure. Modern approaches relate nonlinear dynamics of to minimisation of certain functionals to which direct methods from the calculus of variations are applied. Young measure solutions are constructed by weak conver- gence methods. I propose the investigation of existence of Young measure solutions for problems in nonlinear elastodynamics (especially systems of mixed-type exhibiting co-existence of phases) and the regularity properties of measure-valued solutions. At the end of the fellowship I expect to have acquired a better understanding of nonlinear continuum theories and familiarity with modern mathematical techniques. These problems share features with physical models of modern materials such as martensitic solids or shape memory materials. Thus their mathematical understanding should benefit industrial developement. Furthermore, a problem from gauge theo- ries is also proposed, namely the Ginzburg-Landau superconducting gradi- ent flow in a bounded domain.  Key Words: Young measures, nonlinear elasticity, weak convergence, calculus of variations, systems of conservation laws.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'A territorialised Agricultural Knowledge and Innovation Systems framework for agroecological transitions' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

European food systems face sustainability challenges related to environmental degradation, nutritious and healthy sustainable food access, and just socio-economic development. Increased organic farming adoption positively influences these systems, especially when framed under a territorialised agroecological approach that emphasises local resource use and ecosystem services. Agricultural Knowledge and Innovation Systems (AKIS) can support this transition. However, mission-oriented AKIS supporting knowledge-intensive farming methods and territorial development are recent and poorly implemented, presenting barriers for specific farming groups, especially agroecology-oriented organic farmers. The proposed project aims to develop a transformative and territorialised AKIS framework for agroecological transitions, using a transdisciplinary and interdisciplinary approach incorporating a hybrid Actor-Network Theory/Social Network Analysis methodology in four Spanish case studies involving theoretical, empirical, and practical validation. The applied methodology will assess the patterns, connections, and gaps between territorial AKIS infrastructure for organic farmers and the support required for agroecological-oriented farming practices and innovation using a robust conceptual and analytical framework and participatory-action research through an advisory team and local collaborator groups. The knowledge obtained in this project will be used to develop strategies to promote the objectives of the European Green Deal and EU Missions concerning sustainable food systems. The Fellow will gain new research skills and build and maintain research networks, advancing her food governance and policy research and consultancy career. Combining prior knowledge with acquired expertise, she wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'FIDELIS: Establishing A European Network of Trustworthy Digital Repositories' (FIDELIS) under Horizon Europe.

assistant: **Objectives**

The European Open Science Cloud (EOSC) aims to develop a web of FAIR (Findable, Accessible, Interoperable, Reusable) data and services for science in Europe. In order to achieve a sustainable EOSC, Trustworthy Digital Repositories (TDRs) providing long-term preservation services are required. The FIDELIS project aims to establish a healthy, vibrant and self-sustaining network of TDRs that will foster a supportive open science environment and guarantee FAIR data sharing also in the future.  Within its three-year lifetime, FIDELIS will set up, develop, and operate a European network of trustworthy repositories that will support the development and growth of TDRs within the EOSC ecosystem; foster harmonisation and interoperability across repositories to enable an EOSC federation of TDRs; and strengthen the upskilling of repositories and expansion of the network through an active training and support programme.The word Fidelis comes from the latin Fides and means trustworthy, faithful, loyal, dependable, true. In Ancient Rome, Fides is everything that is required for honour and credibility, from fidelity in marriage, to contractual arrangements, and the obligation soldiers owed to Rome. It is also the name of the goddess of trust, faithfulness and good faith (bona fides).


**Keywords:** trusted digital repositories, data, data management, data preservation, European open science cloud, FAIR, federation