RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Supersymmetric Dark Matter  and Collider Phenomenology' to be submitted under Seventh Framework.

assistant: **Abstract**

The compilation of the recent cosmological data from experiments in cosmology and astrophysics, and in particular of those of the WMAP satellite, confirm with greater accuracy the standard cosmological model.  According to them the current energy density of the Universe is comprised by about 70% of dark energy and 30% of matter,  most of which is in the form of non-baryonic dark matter (DM).  It has been appreciated for some time that the lightest  supersymmetric particle (LSP) is a suitable candidate for this non-baryonic cold dark matter. The LSP is stable in supersymmetric models where R-parity is conserved, and its relic density falls naturally within the favoured range if it weighs less than 1 TeV. In this case the most of the parameter space of the supersymmetric models can be  explored by the future high energy experiments, like these that will be performed at LHC collider at CERN after about two years and at the International Linear Collider some years later. This, in conjunction with  the  upcoming  information from  projects like  the PLANCK satellite and the various neutrinos telescopes, will provide us with the unique opportunity to comprehend the fundamental physics beyond the Standard Model of the particle physics.  We will study the effect of the presence of CP violating phases on direct and indirect DM experiments, in the context of variants  of the Minimal Supersymmetric Standard Model (MSSM), and  we will impose the  cosmological constraints by estimating precisely the neutralino relic density.  In doing so, we will explore the complementarity between the accelerator and DM searches. In addition, we will investigate the possibility of  baryogenesis  through leptogenesis  in this framework. On the other hand, we will study the possibility that the LSP i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Fish Indicatiors of Stress and Health (FISH): Validating the use of embryos and yolk sac larval zebrafish as a model for the study of nociception and veterinary drug testing' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The zebrafish (ZF) is now a widely accepted vertebrate model for research in genetics, neuroscience and development due to its sheer experimental convenience and also its gene, developmental and functional homologies with mammals. ZF are also exploited as a novel model in nociceptive or pain research in a number of laboratories. We are already assessing behavioural and physiological responses in adult ZF to pain but wish to also explore whether embryonic and larval forms offer a useful alternative to adults. This project has three stages. First, using a sophisticated video capture system and automated computational analysis of behaviour, we will compare the behavioural responses to different pain modalities of non-protected larval stages with adults from our current NC3Rs study. This will establish quantifiable behavioural responses to potentially painful stimulation in the larval model. Second, we will characterise the molecular pathways of nociception through a genome-wide analysis of gene expression of the central nervous system (CNS). The screen will be implemented using RNASeq on Illumina and results will be correlated with behaviour. The functional impication of gene responses will be explored by modelling responding genes within a zebrafish regulatory gene network model which will be compared with equivalent mammalian data. We will validate a selection of known and novel candidates by PCR and further in situ hybridisation will determine the precise location of expression in the CNS and adult brain producing a 3D map of brain activity using light sheet microscopy. A third objective is to test a range of analgesic drugs to define which are the most effective in reducing the pain-related behavioural responses and to establish a reliable protocol for wider analgesic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Personalised Access to Local Information and services for tOurists'.

assistant: **Objectives**

Tourism is one of the major European economical, cultural and social enterprises. However, information and services are often inadequate to the user needs and requests. Tourists are usually projected into an unknown environment where it is difficult to identify services points. At the same time, information and service needs are commonly in real time. At present, tourist information is mainly based on paper guide or on information points in relevant tourist positions. Therefore, this is a static source of information. The PALIO project will design an open communication and information architecture to support tourists for an efficient navigation and interaction in a physical space. It aims to permit the implementation and the usability of new services in a transparent way for the user.Objectives:The aim and ambition of this project is to provide new and free tourist services, directly available for tourists and citizens by developing and implementing complex data systems with user friendly and personalised interfaces. The design of the PALIO service is driven by the combination of some new concepts as: personalisation, accessibility anytime, from anywhere and with any communication technology, real-time interactions.These objectives will be achieved through the development of some technological and service innovations and in particular:- Integration of mobile and fixed telecommunication networks;- Methodologies and technologies for the design of scalable and personalised access, information and services;- Tools for service personalisation and for interaction through mobile and portable terminals.Work description:The PALIO system is based on the concurrent adoption of the following concepts:- Integration of different (wireless and wired) telecommunication technologies to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Next-Generation Electrochemical Technology for the Treatment of Hospital Wastewater: Electrogenerated Sulfate Radicals for Complete Destruction of Persistent Pollutants' in the context of a Seventh Framework call.

assistant: **Objectives**

Hospital wastewater effluents have been identified as the primary sources of DNA-damaging compounds, and are considered as the major source of antibiotic resistance in the environment. They exhibit significantly higher pollution, up to 3,500 mg/L of chemical oxygen demand, compared to municipal sewage (i.e., 100-500 mg/L).There is no established technology for the treatment of hospital wastewater. Biological treatment is incapable of degrading more persistent contaminants, e.g., organohalogens, cytostatics, and antibacterial agents. Reverse osmosis membranes are very energy intensive, and generate large amounts of retentate that requires further treatment. The major constraint of chemical oxidation processes is the requirement for high chemical dosages for heavily polluted hospital wastewater.This project proposes a next-generation technology for the treatment of contaminated hospital wastewater, based on the electrochemical generation of sulfate and hydroxyl radicals. Highly oxidizing sulfate and hydroxyl radicals are formed by applying current to an anode at atmospheric temperature and pressure. Excellent preliminary results achieved show an outstanding capacity of the electrochemically generated sulfate radicals in removing persistent organic contaminants at up to 80 times higher rates than with hydroxyl radicals alone. Sulfate radicals react mainly through electron transfer and hence are less subject to scavenging by the background matrix, which allows their accumulation in the solution and drastically enhances the oxidation efficiency.The process offers several important advantages over existing oxidation technologies as it does not generate secondary pollution, has no pH limitations and does not require any external activators (e.g., iron). The project will develo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Toolless Manufacturing of Complex Structures' under Horizon 2020.

assistant: **Concept**

Lithography based additive manufacturing technologies (L-AMT) are capable of fabricating parts with excellent surface quality, good feature resolution and precision. ToMax aims at developing integrated lithography-based additive manufacturing systems for the fabrication of ceramic parts with high shape complexity. The focus of the project is to unite industrial know-how in the field of software development, photopolymers and ceramics, high-performance light-sources, system integration, life cycle analysis, industrial exploitation and rewarding end-user cases.The consortium will provide 3D-printers with high throughput and outstanding materials and energy efficiency. The project is clearly industrially driven, with 8 out of 10 partner being SMEs or industry.Targeted end-use applications include ceramics for aerospace engineering, medical devices and energy efficient lighting applications. The consortium is aiming to exploit disruptive applications of L-AMT by developing process chains beyond the current state of the art, with the dedicated goal to provide manufacturing technologies for European Factories of the Future.By relying on L-AMT,  ToMax the following objectives are targeted: (1) ToMax will provide methods which are 75% more material efficient with respect to traditional manufacturing (2) Are 25% more material efficient with respect to current AMT approaches by using computational modelling to optimize geometries and by providing recyclable wash-away supports.(3) ToMax will provide methods which are 35% more energy efficient that current AMT approaches by developing 50% faster thermal processing procedures.(4) Incorporate recycling for the first time in L-AMT of engineering ceramicsOverall, the consortium will provide innovative, resource efficient manufacturing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The EU-HEALTH INNOVATION MARKETPLACE, the valorization platform for (FP7 Health and H2020 SC1) research results' goes beyond current state-of-the-art under FP7.

assistant: **Innovation**

A recent evaluation of FP7 projects executed by the EC, showed that an estimated 80% of funded Health projects lacks valorisation. The “UTILE” proposal presents the EU-Health Innovation Marketplace, an online tool to better valorise the FP7 Health and Horizon2020 SC1 project results. This marketplace will actively bring together Innovation Providers (i.e. technology push) and the Innovation Developers (i.e. market pull). Moreover, in order to bring technology push and market pull successfully together, all 1200 FP7 Health and Horizon2020 SC1 projects will not only be analysed and defragmented by five high quality TTO’s (including NIH) in a LEAN process. It will also be valued by an elaborate Market & Stakeholder Advisory Committee, existing of Business Developers of 20-35 important pharmaceutical, medtech, biotech companies and Venture Capitalists. Thus here, valorisation of Health results will not be enhanced by just pushing harder, but by defragmenting and presenting these results in a way that the market will better recognize the added value. In addition to the presentation of well valued selected results on the online UTILE Marketplace, technology push and market pull will be actively brought together by a series of offline activities such as specific workshops and roundtables at international and conferences, brokerage events and technology valorisation courses and trainings. Special attention will be given to the participation of SME’s and involvement of Low Performing Countries. UTILE will deliver a self-sustainable platform of functionalities and activities will also enable the valorisation of future Horizon2020 SC1 projects as well as the many more health-related EC-funded health projects (e.g. in the Marie (Skłodowska) Curie actions). The UTILE Marketplace the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Quantum Coherence and Decoherence in Cavity Optomechanics', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Rapid progress in the field of optomechanics has undergone a paradigm shift in the last two years.  It is now possible to use light to prepare and sense the quantum ground state of a nanomechanical oscillator.  Alongside parallel developments in electromechanics, this success marks the emergence of a third wave of quantum technology based on mechanical systems, following in the footsteps of atomic physics in the 1970s and solid state spin ca. 10 years ago.  The new field of quantum optomechanics faces key challenges on several fronts, including execution of protocols for preparation and readout of nontrivial quantum states, mitigation of fundamental sources of mechanical decoherence, and the search for robust and field-distributable architectures. The following proposal takes aim at this new threshold, exploring fundamental and practical aspects of coherence in a mechanical system optomechanically-cooled to near the quantum ground state. We build upon the capabilities of a state-of-the-art optomechanical system developed by the host group of T. J. Kippenberg at EPFL, consisting of a cryogenically-cooled silica microcavity with strongly coupled, high-Q optical and mechanical resonances.  Using the recent development of quantum-coherent optomechanical coupling, we propose to demonstrate, for the first time, quantum-coherent state transfer of a nanomechanical resonator onto an optical field.  Second, exploiting the tools of cryogenic optomechanics, we seek to observe and control *resonant* coupling of a micromechanical resonator to a two-level-fluctuator for the first time.  Third, building upon developments in the integration of ultr-high-Q SiN nanobeams and Silica micro-disk resonators, we propose to realize a robust chipscale optomechanical system suitable for ground-st
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Service-oriented cross-layer infrastructure for distributed smart embedded systems' under Sixth Framework.

assistant: **Concept**

The goal of the SOCRADES project is to create new methodologies, technologies and tools for the modelling, design, implementation and operation of networked hardware/software systems embedded in smart physical objects. The smart embedded system is to be applied in perception and control systems in intelligent environments, in which enhanced system intelligence is achieved by cooperation of smart embedded devices pursuing common goals. These devices with embedded intelligence and sensing/actuating capabilities are expected to be heterogeneous yet they need to interact seamlessly and intensively over a network (wired/wireless).The middleware technologies to be developed in this project will be based on the Service-Oriented Architecture approach, will be generic to any networking technology or transmission medium, and will provide open interfaces that enable interoperability at the semantic level to any 3rd party. A SOCRADES service is considered a software component which encapsulates device-specific functionality. This functionality is advertised to the system in order to be located and invoked by other networked devices.The SOCRADES approach is to create system intelligence by a large population of small and smart networked embedded devices at a high level of granularity, as opposed to the traditional approach of focusing intelligence on a few large and monolithic applications. This increased granularity of intelligence distributed among loosely coupled intelligent physical objects facilitates the adaptability and reconfigurability of the system, allowing it to meet business demands not foreseen at the time of design. Focus from a functional view will be in managing the vastly increased number of intelligent devices and the associated complexity. Focus from a run-time i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'In situ bioremediation of soil contaminated with chlorinated ethenes and nickel, demonstration of cleanup by an aerobic bacteria'.

assistant: **Concept**

Chlorinated aliphatic organics are a group of serious pollutants in most European countries. They eventually end up in sources for drinking water, hence threatening human and animal health.  Microbial bioremediation is currently being proposed as a cost effective, relatively easy to implement and safe technology which potentially may lead to complete removal of such chlorinated compounds. But successful implementation at real world scale in the soil is an absolute requirement to convince environmental authorities and engineering companies that the biotechnological approach is a cost-effective, non-disruptive, low risk, low energy demanding and relatively simple approach to solving a pollution problem which has reached human health threatening dimensions. For this reason demonstration of the practical and economic feasibility of a full-scale in situ bioremediation is necessary now. Only then it may be expected that the enormous market of in situ soil bioremediation, worth billions of ECUs, will be opened up by commercial enterprises and governmental institutions.  The primary goal of this project is to demonstrate that: a onestep anoxic in situ bioremediation is at present the best solution for cleanup of a soil contaminated with chloroethenes together with a high level of metals (i.e. nickel in this case).  To achieve the goal of this demonstration project the following objectives have been set: - To implement and monitor the process of dechlorination and metal immobilization at full scale and, for more detailed analysis of required adjustments, on a large pilot-scale - To adjust and optimize the in si tu conditions and microbial communities to obtain an optimal rate of complete dechlorination and metal immobilization - To evaluate the project and to inform authorities
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Origin of genomic instability: Understanding the biological influence of inflammation in the initiation of pancreatic tumorigenesis'.

assistant: **Innovation**

Inflammation is suspected to be the first step leading to cancer due to alcohol consumption or tobacco smoking between others. Little is known of how inflammation triggers genetic changes leading to tumorigenesis. Recently, I show that TGFb, a cytokine present during inflammation, is able to generate aneuploidy, polyploidy and plausible chromosomal rearrangements in breast cells. Such effects were mediated through the induction of the epigenetic reprogramming EMT. In view to understand how inflammatory signaling can affect the genome integrity, I design the project Onco-Inflammation, to study one of the most lethal cancer, the pancreatic ductal adenocarcinoma (PDAC), where therapeutic options are greatly limited. Using several mice models of pancreatitis, we will follow the establishment of genomic insults, and in particular focusing in whole genome doubling, nuclear envelope disruption and micronuclei. I will evaluate the genetic diversity present under pancreatitis and weigh the roles of the epigenetic re-programming Acinar-Dutual-Metaplasia as well as the oncogene KRAS, using high-resolution 3D imaging, as well as single cell CNV analysis (Aim1). I will also study the common pathways activated in newly aneuploid cells, in view to find some specific therapeutic target. (Aim2). Several pathways will be tested in an attempt to block cancer initiation and progression. Results will be tested and validated using human samples (Aim 3). At the Host Institution, I will greatly benefit and learn from the scientific guidance from my supervisor, expert in pancreas biology as well as experts in mitosis, genetic instability and bioinformatics. MSCA-IF will be instrumental to develop this initial hypothesis into deeper biological understanding the inflammation and cell plasticity’s