RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Gestalts Relate Aesthetic Preferences to Perceptual Analysis' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

"De gustibus et coloribus non disputandum est."" With this slogan philosophers and lay people alike have dismissed all attempts to understand taste, color perception, or aesthetic preferences. Sense of beauty may just be too individual and too complex to qualify as target of scientific inquiry. Yet, since Fechner (1876), empirical aesthetics has studied the factors determining people’s aesthetic responses to art works and objects, scenes or events encountered in everyday life. Most accounts focus either on high-level concepts such as style, meaning and personal associations, or on low-level statistical properties. While the latter are supposed to be universal and biologically determined, the former are subject to cultural influences, art expertise and individual experiences. Progress in this tradition has reached its limits, which this project overcomes by investigating how Gestalts Relate Aesthetic Preferences to Perceptual Analysis (GRAPPA). Its pioneering working hypothesis is that the way perceivers organize their sensory inputs into meaningful entities (Gestalts) provides the missing link between the two traditional sets of explanations. This hypothesis is fleshed out and tested in a coherent research program linking aesthetic preferences for images of paintings and everyday photographs to general principles of perceptual organization as well as to specific aesthetic concepts like composition, balance and visual rightness. New data from online studies with large samples of images and participants will be analyzed with state-of-the-art computational methods (machine learning) to reveal the critical mid-level factors. This will yield a model to predict aesthetic preference, which will be tested in well-controlled psychophysical and behavioral experiments (e.g., eye-m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Nucleases in homologous recombination: from basic principles to genome editing', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Homologous recombination plays a crucial role to repair DNA strand breaks that may occur spontaneously upon replication fork collapse, during the course of radio- or chemotherapy or in a programmed manner during meiosis. Understanding the molecular mechanisms of re-combinational repair is thus very important not only from a basic research viewpoint, but it is also highly relevant for human health. Here, we will define the function of nucleases in homol-ogous recombination. First, we will study the initial steps in this pathway. We could show previously that the S. cerevisiae Sae2 protein promotes the endonuclease activity of the Mre11-Rad50-Xrs2 (MRX) complex near protein blocked DNA ends. This initiates nucleolytic resection of DNA breaks and activates homologous recombination. Our biochemical setup will be instrumental to define how is the activity of Sae2 regulated by phosphorylation on a mech-anistic level and how physiological protein blocks direct the Mre11 endonuclease. We will ex-tend the study to the human system, and attempt to apply the gained knowledge to improve the efficiency of genome editing by activating recombination in conjunction with the CRISPR-Cas9 nuclease system. Second, we will study how homologous recombination promotes gen-eration of genetic diversity during sexual reproduction. DNA strand breaks are introduced in-tentionally during the prophase of the first meiotic division. They are then processed by the recombination machinery into Holliday junction intermediates. These joint molecules are preferentially converted into crossovers in meiosis, resulting in exchange of genetic infor-mation between the maternal and paternal DNA molecules. This is dependent on the Mlh1-Mlh3 nuclease through a yet unknown mechanism. We will study how Mlh1-Mlh3 in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Public policies, law and bioethics: a framework for producing public health policy across the European Union by examining concepts of European and universal ethical guidelines'.

assistant: **Concept**

Under the Treaty on European Union, the European Community was given a competence in public health. Article 3(o) establishes a broad aim of making a contribution to the attainment of a high level of health protection". EuroPHEN aims to assist European Institutions in the development of public health by producing an explicit ethical framework for public health. The project will compare and contrast approaches in public health in Member States and document specific public health priorities and priorities. Various ethical theories, concepts and traditions will be applied to the practice of public health. Empirical research will collect the values of European Citizens assessing attitudes to public versus private interest and on public health interventions at a National and European level. Six focus groups will be held in each Member States within the European Union plus Poland. Groups will be classified according to the age, life stage, gender and socio-economic groups of participants."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Predictive and Accelerated Metabolic Engineering Network' (PAcMEN) under Horizon 2020.

assistant: **Objectives**

The world economy is dependent on fossil resources: oil, gas and coal. The fossil resources are finite and their consumptioncauses catastrophic environmental changes. Therefore we need to move towards sustainable economy using renewableresources for energy and chemicals production. Via metabolic engineering approach, novel microbial cells can be createdthat can convert biomass and waste into fuels and chemicals. Metabolic engineering however distinguishes itself from otherengineering disciplines by low predictability of the design and long turnover times for the cell factory construction and screening. Therefore there is a need for scientists, who can address these challenges.European Training Network on Predictable and Accelerated Metabolic Engineering Networks (PAcMEN) will be establishedat 5 renowned European universities and 2 SMEs with participation of 5 industrial and 1 academic partner organizations. In this program 16 PhD students (of which 15 funded by EU contribution) will learn to conduct state-of-the-art research on metabolic engineering of microbial cell factories and learn to commercialize innovations. This will be achieved via collaborative research projects under supervision of top scientists from academia and industry, network training, secondments with network partners, training on innovation and entrepreneurship, and individual career coaching. Altogether, PAcMEN training programme will provide young scientists with the ideal combination of scientific, technological, industrial and management skills to prepare them for their role as breakthrough pioneers in the establishment of tomorrow’s biorefineries.The PAcMEN project will have an overall positive impact by strengthening the research networks in the area of metabolicengineering, establishing long-t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'POLICY ADDRESSING CLIMATE CHANGE AND LEARNING ABOUT CONSUMER BEHAVIOUR AND EVERYDAY LIFE' (PACHELBEL).

assistant: **Concept**

At the heart of this project lies the development, trialling and operationalisation of a tool (STAVE), designed to support the work of policy-making for sustainability in real-world settings. The tool will support processes of knowledge brokerage, promoting the appropriate application of existing research findings, and the generation of new knowledge which is focused on specific policy objectives. In substantive terms, the project responds to recent work on sustainable consumption, which has provided compelling arguments about the difficulties entailed in seeking to address anthropogenic climate change by attempting to shift patterns of consumer behaviour. The project will take the form of a series of collaborative problem-focused interventions with policy-makers which will engage with their current work in these areas. STAVE will allow these policy-makers to examine the nature and validity of assumptions about human sensibilities, reasoning and action that are incorporated into the development of policy. The project will yield detailed guidance on how best to utilise STAVE across a variety of organisational and policy-specific environments. It will also generate important insights into the mechanisms by which different sources of knowledge are utilised in the practical activity of policymaking; and into the nature of lay citizens’ practical reasoning and everyday activities, as they relate to the sustainability of their patterns of consumption.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'ARTIFICIAL INTELLIGENCE ENHANCEMENT OF SURGICAL TECHNOLOGY FOR THE REDUCTION OF HUMAN BEHAVIOUR-RELATED SURGICAL ACCIDENTS'.

assistant: **Concept**

BESAFE seeks to support the exploitation of the results from the IBSEN FET project and capture a market opportunity as well as address a poignant societal need, the reduction of intra-operative accidents and surgery costs by means of clinical decision support software.IBSEN has led to the development of a general-purpose novel artificial intelligence tool based on unsupervised machine learning algorithms. The software learns from the behaviour of individuals and their outcomes. It can be adapted for automated early detection and correction of high-risk actions by members of surgical teams.The coordinator of the BESAFE consortium, Afferent Technologies, has expertise in prevention of accidental surgical nerve-damage, a costly and dramatic event, by means of electrophysiological technology. The BESAFE software, endowed with artificial intelligence from the ISEB project, has the potential for a quantum leap in the market.The key deliverables of BESAFE are a) the business plan, with detailed financials and market analysis, as well as an estimate of remaining technical milestones, as required to progress from the IBSEN deliverables to the final certifiable software, b) a demonstration of the use of the Artificial Intelligence IBSEN algorithms to recognise patterns of behaviour (high risk vs low risk) by analysis of machine-user interaction patterns.The final aim of BESAFE is to produce a well-studied investable opportunity for Venture Capital coinciding with an increased interest of these stakeholders in the Artificial Intelligence and Medical Technology spaces.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Pathways towards a 'restorative' Anthropocene: a comparative study of three marginalised land practices, their narratives and regenerative potential across local-global dimensions' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

We are experiencing unprecedented environmental and societal changes at a global scale that affect all living beings on earth at a local scale. The epoch of humanity's impact on the biosphere with its irreversible degradation of ecosystems, devistating pandemics, economic and governance failures, unequal development, social and environmental injustice and discrimination, has a name - the Anthropocene. It is synonymous with destruction, inequality and increased vulnerability driven and accelerated by many factors but primarily by the enduring impacts of colonisation, the industrial revolution and the spread of capitalism. A ‘restorative’ Anthropocene instead sees human activity give back more than it takes.  Such activity can be seen in place-based land practices that regenerate land and ecosystems. However, many of those practices are marginalised or silenced as they emerge from diverse worldviews and narratives that are perceived as incompatible with contemporary scientific natural resource management approaches.This study aims to compare marginalised land practices, their associated narratives, and regenerative potential for land and biodiversity across the local-global dimension, by investigating three cases from the Celtic parts of the UK, Bhutan and Australia using a place-based approach within the framing of a ‘restorative’ Anthropocene. The practices to be compared include fire management techniques of Australian indigenous communities known as ‘cultural-burning’ of the landscape, the Bhutanese cultural practice of Reedum [closing of mountains] and the transition from degraded landscapes to 'rewilding' woodlands in the Celtic parts of the UK. The findings from this research will suggest pathways for how we can apply knowledge from culturally, geographically, onto
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Repurposing manufacturing lines for providing medical and other products and services in case of spiking demand times' in the context of a Horizon 2020 call.

assistant: **Objectives**

RESERVIST aims to establish ‘reservist cells’ that in times of crises can be activated within 48hrs to switch to manufacturing medical products and services that are spiking in demand. Such a ‘reservist cell’ will consist of (i) a backbone network of core companies for manufacturing and testing; (ii) an extended network for further capacities (eg local provision, packaging, distribution, customization,…); (iii) a digital coordination platform and (iv) a pool of experts from the companies of the network. These cells will become operational in case of an emergency/pandemic but to make economic sense, the same approach of rapid flexibility and adaptability will be used to deal with surging demand in ‘normal circumstances’.To realise this concept, we will first work on three levels individually: network level, connected manufacturing/digital manufacturing level and technical level, the latter referring to tweaking manufacturing lines, developing required materials and establishing links with testing/certification. Next, we will demonstrate the repurposing of 5 existing manufacturing lines within 48hrs towards manufacturing of ‘textile PPE’ (surgical and respiratory face masks, medical aprons) and ‘respiratory ventilators’ (invasive and non invasive) that comply with necessary testing and certification and proceed with the embedment of the reservist cells at the partners in the network. We will develop blueprints for further take-up and replication of the concept to other sectors. Within the project we will develop two replication demos: ‘disinfection equipment’ and ‘emergency medical equipement’. To support the Cells we will tap into the worldwide maker community and into relevant OITBs and networks.The consortium is strongly industry-driven, including 4 LE and 7 SMEs comin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Synthesis of Targeted Organometallic Anticancer Drugs and their mode of Action', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The project is designed to study a new class of ruthenium antimetastasis compounds, which provides a flexible scaffold onto which various groups of known biological function can be grafted, in order to identify the mechanism of antimetastasis action and obtain superior compounds. In addition, targets will be identified from these compounds using an innovative bio-analytical method. The generic compound which will be used for the study are based on the general structure, Ru(η6-arene)Cl2(pta), and biologically active groups with known therapeutic function, e.g. that induce cell cycle arrest, will be tethered to the arene ring or attached via the ruthenium centre. Key protein targets will then be identified by laser ablation inductively coupled plasma mass spectrometry (ICP-MS). The influence of the inhibitors will be studied and the effect on drug efficacy explored. Drug binding sites will be identified using a mass spectrometric bottom-up or top-down methods which will be very much useful in directing future drug design.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for '3DCOMPASS: Revolutionizing Solid-State Lithium Battery Manufacturing through Xolography Volumetric 3D Printing' to be submitted under Horizon Europe.

assistant: **Abstract**

3DCOMPASS aims to revolutionize the production of complex shaped all-solid-state lithium batteries (ASSLB) using Xolography volumetric 3D printing, a technology that offers superior speed, resolution, and freedom of shape compared to traditional manufacturing techniques including conventional 3D printing methods. The project focuses on the development of Xolography 3D printing for solid state electrolytes, both polymeric and ceramic, enabling the efficient fabrication of solid-state electrolytes with unexplored architectures. 3DCOMPASS will firstly develop containing Li-conductors and suitable for Xolography process with low optical density (<0.22 for 1cm of path at 405 nm), high viscosity (10-60 Pa s) and high polymerization rates. In a second step the printing process will be optimized in relation to resins formulations to obtain the desired speed (55 mm3/h) and resolution (5-20 µm) impossible to achieve with traditional 3D printing techniques. Finally complex shaped electrolytes will be fabricated by Xolography with tailored architectures to: i) enhance the interfacial area with the electrodes, ii) allow high cathode loadings, iii) increase the critical current density vs. Li-metal. The produced electrolytes will be used to assemble half and full cells with Li-metal as anode and Mn-doped LFP as cathode with the following expected performances: ionic conductivity of the electrolytes >10-4 S cm-1 at room temperature, capacity >400Wh/kg, high resistance to dendrite growth with a critical current density > 0.5 mA/cm2. 3DCOMPASS will provide a new class of materials printable by Xolography and at the same time open the door to a new generation of ASSLB with superior performances allowed by micrometric scale architectures possible to produce in a fast and scalable way. Fur
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Responsive and Flexible: Living and learning researcher career development framework' in the context of a Seventh Framework call.

assistant: **Objectives**

Systematic and focused career development is becoming increasingly important for both researchers and their employers. Variety of career management tools is currently available to help them with this challenge. Although many of these tools are very effective in certain contexts they are not simply transferable to another. REFLEX project will try to address this problem through bottom-up approach based on direct involvement of researchers, HR departments, EURAXESS Service Centres and other relevant stakeholders in the design and implementation of flexible, living and learning career development framework adaptable to variety of national and institutional backgrounds. The pool of different career development tools and practices will be collected and analysed. Scenario workshops with researchers and other local stakeholders reflecting on identified factors influencing researcher’s career will be organised in every project country to learn about the country specific situations. A set of modules will be defined describing the particular practices, procedures and skills, which will be combined into the common framework and its country specific mutations. Pilot implementation process will be carried out within the project partners’ institutions/countries. National training models focusing on the development of career management skills for researchers as well as potential future coaches/facilitators will be created and pilot tested. Mutual learning and feedback activities will be carried out to ensure the coherence and continuous improvement of all project outcomes. In order to increase the transferability of the framework to other national and institutional contexts, European level workshop will also be organised before the end of the project. Special EURAXESS training model s