RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'European Network In Geometry, Mathematical Physics, and Applications' (ENIGMA).

assistant: **Concept**

Geometry traditionally played a central role in the mathematical formalism of physics. The relationships between geometry and mathematical physics received a great impetus from the discovery of the integrability phenomenon. This conceptual breakthrough produced many exciting new ideas in mathematics and physics during the last 35 years. Geometry and mathematical physics grew even closer after the discovery that the Korteweg - de Vries equation plays a fundamental role in the matrix and topological models of two-dimensional quantum gravity and the geometry of the moduli spaces of stable algebraic curves. Moreover the genus expansion of the partition functions of 2D topological field theories is intimately related to the weak dispersion expansion in the theory of nonlinear waves. The study of the geometric structure of asymptotic solutions of classical and quantum systems, both discrete and continuous, will lead to applications to physical problems. Matrix integrals, introduced in the statistics of nuclear energy levels, proved to be connected with quantum gravity, conformal field theory, solutions of soliton equations, moduli spaces of algebraic curves and vector bundles, singularity theory, Gromow-Witten invariants. Random matrices and random permutation problems, including certain stochastic processes, have also appeared on the scene in relation with sorting problems in combinatorics, multivariate statistics and growth models. European scientists, so far scattered all over Europe, have played and continue to play a leading role in this research. The main scope of the ENIGMA Programme is to establish a European Network on Integrability, Geometry, Matrix models and Applied mathematics, to provide a fruitful training ground for students and young researchers, by unifying
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Genetic Strategies for an HIV Vaccine Evaluated in the Macaque Model' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

Biological containment space capable of housing HIV- and SIV-infected macaques in European Primate Centres is a key restricting factor in the use of the macaque model for the development of a preventive vaccine against HIV-infection and subsequent progression to the human acquired immunodeficiency syndrome (AIDS). A EU-Concerted Action (CA) Genetic strategies for an HIV-vaccine evaluated in the macaque model" shall be established to ensure their effective use, and reduce their overall numbers in combination with an improvement of their wellfare.Within the proposed Concerted Action we intend to explore the use of specific vaccinia vectors, which are apathogenic in humans, as a means of reproducing the protective effect of live-attenuated SIV without the safety problems connected therewith. The vectors are derived from the highly attenuated vaccinia virus strain Modified Vaccinia Ankara (MVA). The partial protection achieved with MVA-vectors expressing only the gag, pol, and env genes of SIV- or HIV-1 strains (what has been demonstrated by Hirsch et al. 1994) can possibly be enhanced by vectors expressing regulatory genes of SIV or HIV or by an immunisation schedule including boosting with alternative replicating vaccine vectors.Monkeys will be immunised, and their immune system will be monitored before and during the vaccination period. Depending on the outcome of the vaccinations and also on the state of knowledge at that time, a challenge exposure will possibly be performed. For this challenge experiment the construction of new SIV/HIV-chimeric viruses might be necessary and is included as a further aim of the project."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Provizio Accident Prevention Technology™ Platform' (P-APT).

assistant: **Innovation**

Provizio is radically transforming vehicle safety with our proprietary Accident Prevention Technology (APT) platform.Human error is the fault in 90% of car accidents. Over 1.35 million people are killed every year on the road (equivalent to 20airplane crashes every single day) + 50 million injuries [World Health Organisation] = a cost USD $24 trillion (2%+ ofworldwide GDP) [International Road Assessment Programme, iRAP] . More than $80 billion has been invested in ADAS overthe last 5 years [Brookings Institute]…with zero impact on road deaths.Provizio was founded by a team of automotive and aerospace industry veterans with a mission to use advanced technologyto reduce the devastation caused by road accidents. Our skill sets include entrepreneurship, scaling start-ups to exit, VCfund raising, building strong defensible IP portfolios as well as an enviable track record in developing the most advancedtechnology in automotive radar.This proposal outlines the further development of the APT Platform. APT combines proprietary vision sensors and machinelearning to see further, wider and through obstacles, detecting danger in all-weather conditions and applying predictiveanalytics in real time to augment driver behaviour…and prevent accidents.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The Interactive Vision between Architecture and Photography' (INVISA) under Seventh Framework.

assistant: **Objectives**

In schools of architecture students often rely on images; rarely do they have hands-on experience with the actual building. We may say that our first idea of an architectural work comes from looking at a picture, normally a photograph. Yet photography invariably involves a mode of beholding which preconditions not only our perception of an object but also our conception of it and our idea of our relationship to it and with it. The research we propose to undertake aims at studying architecture and photography during the historically decisive period of the Modern Movement, the epoch that has so influenced and inspired contemporary architectural design. The main aim is to create a groundbreaking catalogue (in print and online) that crucially will help to fill a major scholarly gap: that between the three-dimensional work of architecture and its two-dimensional representation (the real object and its simulacrum). The catalogue will be achieved by cross-referencing the published material in major European architectural reviews with photographs preserved in the archives and connecting the images of each building with its plan. The process will generate an active tool of knowledge for the architectural work in question, with a rationale similar to that achieved by Dr François Penz in 6th FP project New Millennium-New Media; the applicant will also benefit from the internationally recognized background of Cambridge University, the foremost school of architecture in Europe. The proposal fully corresponds to the objectives of the IEF: with the European institutions involved it will develop the first network of architectural resources to promote a stimulating dialogue between academic communities across the Continent; making the historical heritage available in a way that will be
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Sustainable Drop-In Transport fuels from Hydrothermal Liquefaction of Low Value Urban Feedstocks' (NextGenRoadFuels) under Horizon 2020.

assistant: **Objectives**

The objective of the NextGenRoadFuels project is to apply advanced HTL technology and subsequent upgrading to a selected range of low value/cost, concentrated biogenic residues from urban activity, in order to obtain cost competitive, sustainable drop-in quality synthetic gasoline and diesel fuels. From a highly efficient and validated baseline HTL process chain designed for lignocellulosics, new innovative process steps will be designed and existing steps optimized to address the additional challenges encompassed by such feedstocks, exemplified by sewage sludge, food waste and construction wood waste (termed urban feedstocks), with the objective to reach similar performance as for lignocellulosics.  The main optimization targets are - To establish fundamental pretreatment process and parameters to provide highest possible organic dry matter content in feedstock slurry and efficiently remove valuable inorganics that can have added value as organic fertilizers and/or soil improvers.  - To establish HTL processing parameters giving highest possible carbon and energy yields to oil phase - To establish efficient upgrading schemes to bring the HTL intermediate bio-crude to drop-in gasoline and diesel fuels - To close material and energy streams to and from the individual process steps in order to obtain maximum internal utilization and minimal environmental impact - To establish MFSP scenarios demonstrating cost-competitiveness, socio-economic benefits and superior LCA and GHG reduction effects in a pan-European as well as global perspective.  Specific targets of the NextGenRoadFuels project are to demonstrate the potential to convert more than 100 M tons urban feedstock per year into almost 500,000 barrels per day of drop-in diesel and gasoline fuels (more than 10 % of the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'New uses for X-ray Tomography in natural building stones: characterization, pathologies and restoration of historical and recent roofing slates' (TOMOSLATE), addressing dissemination and exploitation.

assistant: **Impact**

Europe is nowadays the world’s leading producer and consumer of roofing slate. Slate quarries are found in most European countries. However, despite their importance as a building stone, roofing slates are a relatively unexamined material. In comparison with other building stones, there is a lack of research and scientific publications on roofing slates.Applying expertise in X-ray micro-Computed Tomography (MCT) for the study of roofing slates will make it possible to determine several unresolved issues concerning these rocks:Evolution of mechanical behaviour during freeze-thaw cycles of slate tiles. From an engineering perspective, this fact is crucial when deciding which type of slate should be used in a building, especially in areas with high temperature oscillation.Loss of fissility of slate blocks during the production process under dry conditions. This phenomenon forces the blocks to be submerged in water during the production process, severely inconveniencing producers.Evolution of mineral changes during weathering cycles. Observing the evolution of these minerals during weathering cycles will provide a clear understanding of how they really affect the integrity of the slate, and which concentrations should be considered dangerous.Technological characterization of roofing slate and other rocks suitable for roofing. By characterizing slates with MCT it will be possible to obtain a 3D representation of the optimum microscopic structure of a roofing slate.Development of a methodology to determine the origin of historical slate tiles, and, should they need to be replaced, for selecting the most appropriate type of replacement slate. This is very important, since frequently the original quarries are exhausted, forcing restorers to use foreign slates.From an economic a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The role of c-myc in the process of keratinocyte differentiation' to be submitted under Fourth Framework.

assistant: **Abstract**

Research objectives and content The epidermis forms the outer covering of the skin. Keratinocytes, the major cell type of the epidermis, are organized into four distinct types of cell layers: basal, spinous, granular and cornified. The proliferative compartment, the basal layer, contains at least two types of keratinocyte: stem cells with an unlimited capacity for self-renewal, and transit amplifying cells which withdraw from the cell cycle and differentiate after a few rounds of division. Stem cells express two fold higher surface levels of betel integrins than transit amplifying cells. The transcription factor c-Myc stimulates terminal differentiation by driving entry of stem cell progeny into the transit amplifying cell compartment. The objectives of this project are first to study the in vivo effects of overexpressing c-Myc in keratinocytes using transgenic mice, and second, to find out whether in keratinocytes integrin genes are directly regulated by c-Myc. Training content (objective, benefit and expected impact)  The project will allow me to join the field of differentiation processes and to be trained in mammalian molecular biology, mammalian cell culture and histological techniques.  Links with industry / industrial relevance (22) l
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Assessment of LIquid Salts for innovative applications' under Sixth Framework.

assistant: **Concept**

Among other fluids like water, sodium and gases, liquid salts score high in terms of heat transport and heat transfer properties (large heat capacity, high boiling point, good conductivity).In the Generation IV programme built on behalf of the MSR (Molten Salt Reactors) Steering Committee, more attention is given to:- Heat transport between a heat source and specific processes (hydrogen production,...);- Liquid salts as efficient coolants for solid fuel reactors, in alternative to sodium and helium in fast or thermal reactors;- Molten salts acting both as fuel and coolant in MSR concepts operated either as breeders in thorium cycle, or as actinide burners for LWR spent fuel recycling.Liquid salts also present a generic interest as solvents in pyrochemical techniques. Molten salts were investigated in USA in the 60's and 70's in the frame of programmes dedicated to the development of MSR breeders. The ORNL considerable amount of results forms a reference set of data on liquid salts properties and behaviour.The MOST project, supported by the Euratom 5th FWP, revisited the potential of MSR technology. Since the termination of the project in 2004, the collaborative effort conducted by the MOST partners has remained vivid. This network involves today 15 partners in 9 countries and includes Russia, therefore keeping a tight link with the ISTC-1606 project.The ISTC-1606 training programme is provided to Russian experts by scientists belonging to the European network on molten salts. The main objective of the ALISIA action is to strengthen, within an official European framework, the existing network on molten salts technologies, and to prepare future activities in the 7th FWP.Planned for 12 months, ALISIA will produce a review report making recommendations on the best adequate
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Digital Ontology-based Modelling Environment for Simulation of materials', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

SimDOME aims to develop an industry-ready software framework for materials modelling interoperability, based on EU/EMMC standards on materials modelling, by combining, further developing and adapting existing software developed within previous EU FP7-NMP projects SimPhoNy and MoDeNa, the H2020-NMBP project NanoDome and the FP7 ERC-AdG STRATUS. SimDOME achieves the highest level of interoperability through the standardization of the material users case (i.e. the material/process to be simulated, according to EMMC definitions) that are provided within the SimDOME framework by means of the European Materials Modelling Ontology (EMMO). User case standardization will allow data communications between software by translating the concept of each specific implementation to the standard unified concepts and interfaces provided by the ontology.The framework will provide also ready-to-use modules that cover different industrial applications and materials modelling fields spanning through multiple scales. The demonstration of the exploitation potential of the framework will be done within project by testing the SimDOME framework prototype and each integrated modelling software in their respective industrial operational environments (TRL 7) in the fields of gas and liquid phase material synthesis, molecule characterization and chemical kinetics.SimDome will integrate and provide the upscaled software and services for maintenance and support via the existing and future European Materials Modelling Marketplace (EMMM), the network of modelling translation environments and the Open Innovation modelling test beds.A strong relation with the EMMC, EMMM and existing projects is guaranteed by the fact that most of the SimDOME proponents are active members of the EMMC, leading the EMMO develo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'EPIGEN: A New Predictive Response Test for Non Small Cells Lung Cancer Treatment' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

EPIGEN test is a ready-to-use tool capable to lead the oncologist to the best Non Smal Cell Lung Cancer treatment, the most common subtype of lung cancer (80% of cases). The standar treatments to combat NSCLC are both chemo- and radiotherapy, but many patients (up to 65%) presents resistance, and currently there is not any tool available for the clinician to predict it. The EPIGEN test will allow the clinician a patient stratification in terms of the patient susceptibility to radio- and chemotherapy, and therefore lead for a personalyzed prescription. The EPIGEN test tecnology is based on the determination of the methylation percentage of the epigenetic biomarker IGFBP-3 in the patient tumor samples. The methylation percentage of IGFBP-3 is determined by using qMS-PCR (quantitative methylation specific polymerase chain) tecnique, a well known and extended biochemistry tecnique. The methylation percentage provided by using the EPIGEN test protocol and reagents in the qMS-PCR tecnique will lead the clinician for the optimal NSCLC treatment, avoiding the possible patient resistance to chemo and radiotharapy, and therefore unnecesary side effects and costly therapies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Enhanced Light Solution for Sustainable Cropping' (ENLIGHT), addressing dissemination and exploitation.

assistant: **Impact**

The need for food continuously increases as the world population is growing (estimated to reach nearly 10 billion by 2050 (>30% higher than today)). To meet their food needs, 56% more crop calories will be needed in 2050. Farmers are in dire need for innovative sustainable technologies to boost crop yields without increasing production costs and energy use. There is no silver bullet to achieve food security, hence adopting sustainable solutions and integrating technologies that sustainably enable climate resilient crop production has become a current priority.CASCADE, a French SME, has developed a game-changing disruptive solution in the form of masterbatches using its LIGHT CASCADES® technology to shift a portion of the sunlight spectrum, little used by plants, into wavelengths most efficiently used for photosynthesis and plant development. This LIGHT CASCADES® technology can be incorporated into greenhouse film covering high-tunnels, low-tunnels, and glass houses ultimately benefiting growers. In addition to boosting yields, our technology makes growing food sustainable by significantly reducing water, fertilizer, and pesticide use. CASCADE aims to capture 2.5% of this market by 2024 (revenue 19 M€) with 11 customers (large greenhouse film manufacturers) and estimates a serviceable obtainable market of 800 M€. With the EIC Accelerator funding the company will be able to test its multi-season LIGHT CASCADES® technology in operational conditions for enabling commercialization. Upon successful commercialization, LIGHT CASCADES® technology with its conservative estimate of 10% yield increase potential, will result in more than 1 million metric tons of additional horticultural produce (fruits and vegetables) in the EU region alone. This additional yield contributes to redu