RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Magnesium Sulphate Administration for Prevention of Eclampsia : Reducing the Human and Health Service Burden Associated With Hypertensive Disorders of Pregnancy' (1994-1998).

assistant: **Innovation**

* To estimate the overall effectiveness and safety (for women and their babies) of magnesium sulphate when administered, within the existing health services, to women with pre-eclampsia.* To contribute to The Cochrane Library by preparing and maintaining systematic reviews of the care of women with severe pre-eclampsia, and by ensuring that the implications for practice within developing countries are discussed in Cochrane reviews relevant to the care of women with hypertension during pregnancy.* To enhance and strengthen existing collaborative networks within developing countries, and to increase the capacity to conduct high quality primary and secondary research and to implement appropriate evidence into practice.Expected Outcome* This trial will provide reliable evidence, of direct clinical and policy relevance, about the effectiveness and safety of magnesium sulphate for women with pre-eclampsia and their children.* If magnesium sulphate is effective, this study will allow economic evaluation to determine cost-effectiveness in a variety of settings.* The results of this trial are likely to suggest hypotheses for the pathophysiology of eclampsia, and the mode of action of magnesium sulphate.* This project will contribute to the mission of the Cochrane Collaboration by making available Cochrane reviews relevant to the care of women with hypertension during pregnancy.* This project will strengthen the capacity within developing countries to design and conduct high-quality multicentre randomised trials.* Develop a common core protocol for a trial to evaluate the administration of magnesium sulphate to women with pre-eclampsia.* Conduct a collaborative randomised trial evaluating magnesium sulphate. Women with pre-eclampsia will be randomised to receive either magnesium
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Novel business model enabled by a patented fermentation technology to produce 100% biodegradable textile fibres from CO2-emissions' (CO2TEXTILE), addressing dissemination and exploitation.

assistant: **Impact**

Our innovation is the creation of a disruptive business model in the textile industry by establishing a new interconnection between two industrial value chains that are typically not connected: CO2-emitting industry such as energy intense sectors, e.g. chemical industry, and the textile industry. The innovation is enabled by our patented fermentation technology which turns harmful industrial CO2-gases into valuable, 100% biodegradable biopolymers. We capture CO2 emissions before their release into the atmosphere and use them as feedstock to produce added-value PHA biopolymers through a highly efficient, high-yield fermentation process. In this process, 2.5 tonnes of CO2 are turned into 1 tonne of PHA biopolymer, from which textile fibres are produced and sold at current market prices (1/kg). The material can be used for several years and fully decomposes within 1 year in industrial or home compost conditions or in the marine environment, thus preventing plastic pollution.


**Keywords:** Bioprocessing technologies,Environmental and Green Technologies,Microplastics,Bioeconomy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Mechanistic analysis of DNA damage signaling and bypass upon replication of damaged DNA template in human cells.' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The genetic information encoded by DNA is under constant attack from both endogenous and exogenous sources of damage. To ensure genome stability and prevent disease, cells use global signaling networks to sense and repair DNA damage. One particularly serious problem is when the replication machinery encounters lesions remaining in the template DNA. In this scenario, cells employ damage bypass mechanisms to complete genome replication and prevent fork breakage. Importantly, these pathways are not restricted to the site of stalling but can also function behind the fork at single-stranded DNA (ssDNA) gaps originated by the re-priming of DNA synthesis downstream of lesions. While it is very well known that ssDNA is the molecular signal that triggers the checkpoint response, it is less clear how and where ssDNA actually arises. Generally, it is assumed to accumulate at stalled replication forks, either by an uncoupling between replicative helicase and polymerase movement or between leading and lagging strand synthesis. However, in a recent study in budding yeast, I found that ssDNA gaps left behind replication forks, and extended by processing factors such as the exonuclease EXO1, constitute the predominant signal that leads to checkpoint activation in response to damaged DNA templates during S phase. Whether this mechanism of checkpoint activation is conserved from yeast to humans remains unexplored. Hence, using a unique set of multidisciplinary approaches, this project aims to address the fundamental question of how DNA damage is sensed during replication in human cells. Interestingly, not only ssDNA gap processing seems important for checkpoint signaling but also for the template switching mechanism of damage bypass. Therefore, this project will also study the function o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'BioMusical Instrument'.

assistant: **Concept**

The BioMusical Instrument project will create a product prototype of a wearable digital musical instrument based on biosignals from the performer’s muscles. It will allow musicians to perform electronic sounds from bodily gestures. Muscle tension will be sensed by innovative new electromyogram sensing hardware packaged in an ergonomic housing and coupled to wireless communication. Sophisticated machine learning methods developed in the ERC MetaGesture Music and H2020 Rapid-Mix projects will track musician gesture and create meaningful relationships with computer-based synthesized sound. The BioMusical Instrument will be marketed to three distinct application areas: First, it will enable “hands-free” performance of electronic music. Second, the visualization of body states will make it a useful training tool in traditional musical instrument pedagogy. Finally, the sonification of physiological signals will allow the instrument to be used in the health sector in physical rehabilitation exercises. The BioMusical Instrument will be the first product to combine EMG sensing, machine learning, and advanced audio signal processing. We have identified partners in the biomedical hardware field, the music technology industry, and rehabilitation research with whom we will benchmark and evaluate the product prototype.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Develop a low cost, positioning and rotating device' (1994-1998) under Fourth Framework.

assistant: **Objectives**

Develop a low cost positioning and rotating device When processing in the fish and food industries large quantities of goods are transported in the factories on conveyor belts. The problems arise when the goods must change direction with exact measures for example to a robot or a machine process. Then the stateof-the-art is to use an expensive and complex electromechanic system. The high cost decreases the use and instead much lifting, turning and sinking movements are done manually. These manual movements in the fish and food industries are often done in chilled rooms or in rooms with low temperature. The low temperature in combination with lifting and turning movements cause a large number of injuries on shoulders, necks and arms. The proposers in this project cooperate in order to develop a new type of low cost, positioning and rotating device which will fulfil the demands of the fish and food industries. The objective is to develop a device - based on a patent of the prime proposer from 1995, see appendix land 3 - which will only cost 1/5 of a electromechanic system with equivalent functions. As the device is of a simple design and requests a minimum of maintenance the mentioned low cost is both a low sales price as a low life-time cost. The overall objective of this research project is to increase the knowledge in this field and solve the technical problems, which impede this developing project. The main problems to solve are - the rotation is not quite smooth, caused by to high retardation and acceleration, when the rotation starts and stops. - the rotation can reverse if a counter force is applied, when the cylinder is in the top or in the bottom position. - how to transmit pressurised air through a swivel with endless movements. The approach to meet the objectiv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'EUROPEAN NUCLEAR DECOMMISSIONNING TRAINING FACILITY (EUNDETRAF II)' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Safety in the nuclear industry at all stages, during the operational activities as well as in decommissioning, is paramount. To maintain high safety standards, sufficient number of qualified and skilled manpower is perpetually required. However, the present situation indicates a rather bleak picture. Due to lack of interests on the part of the young generation and duet somewhat tarnished image, the nuclear industry is not getting sufficient high-grade intake. In addition to that, the existing skill base is gradually eroding due to retirement of the aging workforce. The EUNDETRAF II (European Nuclear Decommissioning Training Facility II), following on the success of the EUNDETRAF I, will address this shortfall in skill base by facilitating transfer of knowledge and skill from the existing and experienced experts to the new generation or new entrants in an accelerated way. EUNDETRAF is a consortium of 11 main European organizations representing educational establishments, nuclear industry operators, R & D organizations and regulatory bodies. The consortium consists of SCK-CEN (Belgium), RWE NUKEM (UK), EWN (Germany), University of Hanover (Germany), Bergamot (Belgium), SOGIN (Italy), CEA (France), NRG (Netherlands), UKAEA (UK), DECOM (Slovak Republic) and INSTN (France). The primary aim of theEUNDETRAF is to pool together knowledge and expertise in the field of nuclear decommissioning from acknowledged European experts and then disseminates them to the wider nuclear industry to improve safety standards and European competitiveness. The mechanism of dissemination of knowledge is by holding training courses. The first training course in 2004 will be held in France, the second one in Italy in 2006. Each training course will be composed of a one-week theoretical and one-week
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'A smile in return' (SMILE).

assistant: **Concept**

The European e-commerce market amounts to ~80 million purchases per day. About 15% of purchased products do not live up to consumers’ expectations and are returned to the vendor. Whether in perfect condition or not, their status as returned product makes items suddenly worth a lot less. What a waste! Not only to e-tailers, who typically lose +80% of the value of returned products, but also to the environment, which is impacted by 4 billion pounds of disposed products and 11 million metric tons of carbon emissions. The problem is expected to grow as ecommerce is gaining market share fast (13.3% growth in 2016).BuyBay helps to solve the problem. The tech-company is developing a data-driven solution that revolutionises the management, processing and resale of returned items. It uses highly innovative pricing software and is unique in its ability to connect inventory management and re-product grading to multiple third party sales channels. The prototype of the Buybay platform is complete and qualified and has recently been tested in in real world settings in the Netherlands and Belgium. Demonstrations have shown that Buybay’s prototype platform has potential for unmatched value recovery (~56% instead of 19.6% of the original retail price currently). Installation of BuyBay’s platform increases re-product revenues for e-tailers, reduces the need to dispose of returned goods and has the potential to reduce re-product selling related carbon emissions of up to 31%. To ensure complete commercial scalability and enable international acceptance by e-tailers of different sizes and in different sectors across Europe, Buybay’s platform requires additional infrastructure development, optimisation through businesses intelligence analysis and scale up testing in operational environments.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Simulation of complex fluids including hydrodynamics: membranes and polymeric systems'.

assistant: **Innovation**

The dynamics of complex fluids, as polymeric or anphiphilic systems, is determined by a subtle interplay between processes in a wide spectrum of time and length scales. These systems, of immense importance in industrial applications and life, are nowadays the subject of active research. Modern computer simulations try to describe their intermediate scales from the underlying atomistic features. Nevertheless, traditional simulation techniques (such as molecular dynamics (MD) for the nanoscale, dissipative particle dynamics (DPD) for the mesoscale, or continuum fluid dynamics (CFD) for larger scales) fail to conform to this task because they were built to separately solve each complexity level. This project will use novel multiscale techniques that link several degrees of complexity. These methods describe the molecular features only at the relevant locations of the system, while using a coarse-grained model to include the hydrodynamic transfers from the bulk flow. This greatly reduces the computational cost , without loss of detail. We shall use two different multiscale techniques: the hybrid particle-continuum scheme derived by the Researcher, Dr. Delgado-Buscalioni, during his Marie Curie period and a new algorithm to cast the entanglements of polymer chain s in DPD simulations.The hybrid model shall be used to study interfacial systems under flow: tethered polymers and membranes. The DPD scheme with entanglements will be used to study star and branched polymers under flow. The local group has a vast experience on membranes and polymeric systems, from both, simulations (via MD, Monte Carlo and DPD techniques) and experiments. Collaborations with other European groups are also planned. The Researcher will be contracted for four years by the UNED with a Resea rch Contrac
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Individual differences in facial expressivity: Social function, facial anatomy and evolutionary origins'.

assistant: **Objectives**

Communicating with others via the face is crucial for navigating our social world. Deficits in facial expression production can have debilitating effects on social interaction, characterising several clinical conditions such as autism spectrum disorder, schizophrenia and Parkinsons disease. Despite this, we know surprisingly little about individual differences in facial expressivity in the typical population, what causes these differences and whether such differences impact on individual lives. In part, this could be due to an historical focus on the universal nature of facial expression, assigning individual difference to random noise, rather than an evolutionarily relevant characteristic. The FACEDIFF project will diverge from this classic approach and test the novel hypothesis that individual differences in facial expressivity equip individuals differentially to engage with their social environment: expressivity has a benefit (social engagement) but also a cost (over-exposure and thus risk of being cheated by others) and is related to the size and quality of an individuals social network. FACEDIFF will combine psychological, anatomical and cross-species methods to provide the first thorough interdisciplinary investigation of individual differences. First, individual variation in production and perception of facial expressions will be measured via laboratory experiments and in relation to social network size and quality. Second, variation in human facial musculature will be documented through cadaveric dissection and existing MRI databases. Third, facial expressivity will be examined in a primate model to determine whether patterns are unique to humans. This project will be the first to provide a comprehensive and interdisciplinary perspective on individual difference
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Preventive and active safety applications contribute to the road safety goals on European roads' (PREVENT) targeting Sixth Framework.

assistant: **Abstract**

The transport policy goals for road safety set by the European Commission for 2010 can only be reached by means of an integrated and holistic approach. Research should focus not only on the crash phase and the post-crash phase, but also on the pre-crash phase, taking passive, active and preventive safety measures into account.The development and rapid dissemination of safety systems can only achieved at competitive costs by defining safety functions, integrating in-vehicle systems and combining them with enhanced telematics into a network of integrated safety systems. PReVENT, as part of the EUCAR Integrated Safety, takes into account the recommendations of the Commission Communication Information and Communications Technologies for Safe and Intelligent Vehicles" COM(2003) 542, Brussels, 15.9.2003. The project supports the Commission actions that aim to promote the development, deployment and use of Intelligent Integrated Safety Systems in Europe. PReVENT will help drivers to avoid accidents Depending on the significance and timing of the danger, the systems will alert the drivers as early as possible, warn them and, if they do not react, actively assist or ultimately intervene.In PReVENT, a number of subprojects are proposed within the clearly complementary function fields: Safe Speed and Safe Following, Lateral Support and Driver Monitoring, Intersection Safety, and Vulnerable Road Users and Collision Mitigation. Additional cross-functional fields have been prioritised regarding the common understanding of functional architectures, validation and impact evaluation principles, sensor data fusion, map related matters and liability issues as well as cohesion of strategies paving the way for early market introduction. After three of the four years of PReVENT, a common Saf
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Walking Old Paths in New Shoes: Individual Trajectories to Retirement and the Welfare State in Austria and Germany' under Seventh Framework.

assistant: **Concept**

This project carries out a comparative investigation of retirement behaviour in Austria and Germany. Drawing on the theoretical concept of ‘pathways to retirement’ (Kohli & Rein 1991) it examines individual trajectories leading to labour market exit both through policy-analysis as well as empirically. The project proposes an interdisciplinary analytical approach and mix of methods. The empirical bases are process-produced work history data spanning over 30 years (linked employer-employee data). A novel sequence-based statistical technique is used to identify empirical typologies of common ‘pathways to retirement’, subsequently used as input in explanatory models of retirement behaviour. The scientific objective is to contribute to our knowledge about the determinants of different retirement behaviours, taking account of a wide, interdisciplinary array of mechanisms through which people allocate to different ‘pathways to retirement’. The project is tailored as to allow the postdoctoral research fellow to reach well-defined objectives in terms of skill acquisition and career advancement. It will allow her to obtain the practical skills necessary for the use of administrative data in applied labour market research and to further advance her skills in econometric evaluation research. Both of these skills have become crucial assets for labour market researchers in public and private institutions.