RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Advanced LINUX-Based pRoducts for Embedded telecommunication solutions' (LIBRE).

assistant: **Concept**

The main objective of the LIBRE project is to integrate and evaluate the open source embedded LINUX Operating System (OS) in the development lifecycle of Embedded Software Products. The project addresses the area of embedded telecommunication applications and will perform a Best Practice Experiment in the scope of a broader project in order to assess the suitable use of LINUX in terms of development effort, reusability, reliability and performance. The LIBRE project will perform a specific experiment which is a part of a larger industrial project, namely the development of an advanced inter-working unit (IWU) between the UMTS UTRAN and the GSM MSC for the migration to 3rd generation mobile communications.Objectives:1. To assess the suitability of the LINUX Open Source Embedded OS for time critical applications such as UMTS / RNC-GSM/ MSC inter-working over the E1 / T1 2Mbps interface;2. To evaluate the efficiency of the embedded LINUX Open Source OS and assess features such as portability, scalability and reusability especially for telecommunications applications;3. To propose potential changes or enhancements on the embedded LINUX Open Source OS in order to enhance performance and efficiency;4. To perform a risk analysis on the usage of the LINUX embedded OS, as a platform for the development of networking embedded applications, focussing mainly in the areas of UMTS and GSM networks;5. Use the sophisticated services of a standard time-shared OS while still permitting real-time functions in a predictable and low-latency environment.Work description:The LIBRE project is organised in 6 workpackages.WP1 deals with the management of the project and the smooth execution of the project tasks.WP2 collects the LIBRE experiment requirements regarding real time in the engineering
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'New operational steps towards an alliance of European research fleets' under Seventh Framework.

assistant: **Concept**

EUROFLEETS2 is the enhancement of EUROFLEETS1, with the aim of developing a new pan-European distributed infrastructure with common strategic vision and coordinated access to Research Vessels (RVs) and marine equipment. EUROFLEETS2 will furthermore undertake specific actions to consolidate research fleets’ organization, methodology and tools through operational initiatives (like virtual fleets) leading to more interoperable and cost effective European research fleets.EUROFLEETS2 main objectives are:* Promotion of operational coordination and integration of RVs. Modern European RVs are made accessible under EUROFLEETS2 (8 of Ocean/Global class and 14 of Regional class) plus 6 mobile pieces of equipment. Further integration is proposed within an innovative multi-platform experiment. The corresponding call aims to identify a flagship proposal, with a proven scientific excellence;* Completion of strategic perspectives for the European research fleets with a polar component;* Promotion of exchanges of mobile equipment on board European RVs to foster interoperability;* Enhancing the impact of research fleets on innovation by fostering the involvement of industry in specific activities, both as end user (e.g. development and testing of new equipment or deep-sea exploration for new resources) or as supplier;* Development of new training actions including a pilot floating university, and of new technological innovations to be widely used on board European RVs;* Making a new step towards a long term sustainable group of European Regional RVs with a view to applying for its insertion into the ESFRI roadmap.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Urban Data Spaces for Green dEal' in the context of a Horizon Europe call.

assistant: **Objectives**

USAGE (Urban Data Space for Green Deal) aims to provide solutions and mechanisms for making city-level environmental and climate data available to everyone based on FAIR principles. USAGE will support the implementation of the European strategy for data and various European Green Deal priority actions at the level where climate change is mostly felt: cities and towns.USAGE will provide innovative governance mechanisms, consolidated arrangements, AI-based tools and data analytics to share, access and use city-level data from Earth Observation (EO), Internet of Things (IoT), authoritative and crowd sources, leveraging on standards for data and service interoperability.USAGE wants to become a decentralized infrastructure for trustworthy data collection, processing and exchange based on commonly agreed principles, facilitating the combination of heterogeneous data for policy analysis.USAGE will validate its solutions in four diverse pilot areas located in four different countries, focusing also on the reusability of the solutions in other urban areas.The consortium consists of 11 interdisciplinary partners from 5 European countries and, within the 3 years of activities, will also realize a long-term sustainability and growth strategy plan of project solutions.


**Keywords:** urban data space, local green data space
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'EUROPEAN NETWORK for CANCER research in CHILDREN and ADOLESCENTS' (ENCCA).

assistant: **Innovation**

ENCCA aims to establish a durable, European Virtual Institute clinical and translational research in childhood and adolescent cancers that will define and implement an integrated research strategy and will facilitate the necessary investigator-driven clinical trials to introduce the new generation of biologically targeted drugs into standard of care for children and adolescents with cancer. This will lead to more efficacious and less toxic therapies that will maximise the quality of life of the increasing number of survivors of cancer at a young age in Europe and allow them to assume their proper place in society. This biologically-driven research agenda will improve training of the clinical investigators and translational scientists of the future to spread excellence, increase capacity to participate in research and monitor outcomes across Europe. Patients and their families will be full partners and will be better informed about the need for and processes of clinical research. They will be in a better situation to care from their long term health risks for children. Drug development will be accelerated in partnership with industry through improved access to young patients with cancer, to academic expertise in care, clinical and biological research. All of this will be achieved with respect for the highest ethical and patient safety standards. ENCCA will bring all stakeholders to the table in a timely and efficacious manner. It will address the needs of all the current multinational clinical trial groups for the benefit of children with cancer. It will provide them with common tools and approaches to solve the bottlenecks in testing new therapeutic strategies for those rare diseases in a vulnerable age group and in running a competitive clinical research agenda. Ongoin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Processing of biomolecular targets for interferometric quantum experiments'.

assistant: **Concept**

Recent studies in Vienna have shown that surprising quantum phenomena, such as matter-wave interferometry with molecules composed of hundreds of covalently bound atoms, are actually feasible.PROBIOTIQUS will now be the first project world-wide to develop experimental tools for matter-wave physics with large biomolecules from amino acid clusters up to proteins and self-replicating molecules.First, we shall exploit the full potential of coherent molecule metrology for biomolecules, and molecules in a biomimetic environment.  This research connects quantum physics with chemistry and biophysics, since already a restricted number of precisely determined geometrical, electrical, magnetic or optical properties may provide tell-tale analytical information. Embedding the biomolecules in a hydrate layer will allow us to study their properties in a context that approaches the ‘natural’ environment.Second, we will develop molecular beam methods, optical manipulation tools and detection schemes to prepare proteins and other large biomolecules for advanced quantum experiments. This includes new laser-assisted acoustic and thermal volatilization methods, slowing and focusing in optical forces, diffraction at ionization and neutralization gratings as well as tagging of proteins with ionizable small biomolecules.Third, we will prepare a cryogenic biomolecular sample in a buffer-gas loaded ion trap, where optical ionization and neutralization will be optimized in order to enable optical diffraction gratings. The target temperature of 10 K will be the starting point for interference experiments with proteins and self-replicating RNA, on the way towards full viruses.Quantum interference with large biomolecules at the edge to life has remained an outstanding challenge throughout the last tw
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'A multi-layered -omics study to understand the dynamics leading to morphological progression in pulmonary fibrosis' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The aim of this research project is to understand the dynamics within the progressing fibrotic lung to identify biologically meaningly interactions which could serve as treatable targets in the future.  Therefore, we will use a spatially resolved study set-up involving multiple layers of cutting-edge -omics technologies wherein the inherent variability will be used as a surrogate for disease progression by in-depth quantification of disease extent using microCT and different staining techniques.


**Keywords:** pulmonary fibrosis, -omics, systems biology
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Why do transcription factors bind what they bind when they bind?'.

assistant: **Innovation**

Transcription factor binding is orchestrated by a complex interplay between DNA sequence, chromatin composition, protein interactions, and transcription factor concentration. These regulatory features determine the binding kinetics: how long it takes for a certain amount of transcription factor to associate, and subsequently dissociate from specific binding sites. These kinetics are in turn determined by the thermodynamic properties of each interaction.It is currently not possible to measure the biochemical kinetics of transcription factor binding across the chromatinized genome inside the nucleus of a cell. To understand why a transcription factor binds to a specific chromatin:DNA-sequence context in a specific cellular state at a specific time, we need to measure how chromatin and DNA influence the biochemical parameters that underpin transcription factor binding. This gap in knowledge limits our functional understanding of why a binding event occurs, and it hampers accurate predictions of transcription factor binding.Here, I will establish a novel proteomics and genomics toolkit to decipher the regulation of transcription factor binding kinetics to the chromatinized genome. I will resolve interactome- and genome-wide binding kinetics of three lung-cancer-associated transcription factors. By delineating association and dissociation rates, and changes in disorder and binding energy, of all binding events across the genome, I aim to obtain a quantitative understanding of how the proteome composition, epigenetic landscape, and genetic code dictate transcription factor binding. Finally, I will build predictive binding models to engineer cell-state-specific transcription factor binding profiles.Together, this will transform our knowledge about transcription factor binding
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Molecular Life of Plants ERA Chair' to be submitted under Horizon Europe.

assistant: **Abstract**

Biology Centre of the Czech Academy of Sciences (BC) together with Prof. Jiří Friml (Institute of Science and Technology Austria, ISTA) are proposing the project “MOLIPEC: Molecular Life of Plants ERA Chair” to create a research centre of excellence in plant molecular biology to increase research quality and capacity at BC, in the Czech Republic and within ERA. Plant research has repeatedly provided key breakthroughs such as discovery of cells, genes or transposons. Modern plant biology has pioneered many major discoveries in all areas of biology. Further molecular insights are essential for developing sustainable agriculture and plant-based industry, all critical to human survival. Plant research has a long-standing tradition in Czechia, however, modern molecular biology remains underdeveloped because of an anti-genetics past legacy in Eastern Europe. Plant research at BC currently undergoes major structural changes providing an excellent and timely opportunity to restructure BC to achieve efficiency and excellence. The ERA Chair will be instrumental in this endeavour. The project comprehensively addresses five most important areas for improvement: (1) The International Advisory Board under ERA Chair direction will strengthen research and leadership at BC from an international perspective. (2) Centralised facilities will provide professional research and administrative support, improving efficiency and economical savings. (3) Outstanding talents will be recruited to establish two new independent research groups complementing current plant research topics. (4) Mentorship program and career development plan will improve R&I knowledge and skills, free circulation of knowledge, and cooperation with business. (5) Targeted communication and dissemination of research results
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'IMPROVING THE AIRCRAFT SAFETY BY SELF HEALING STRUCTURE AND PROTECTING NANOFILLERS' (IASS).

assistant: **Innovation**

Inspection and Maintenance are important aspects when considering the availability of aircraft for revenue flights. Modern airframe design is exploiting new exciting developments in materials and structures to construct ever more efficient air vehicle able to enable ‘smart’ maintenance including self-repair capabilities. The improvement in the aircraft safety by self-healing structures and protecting nanofillers is a revolutionary approach that should lead to the creation of novel generation of multifunctional aircraft materials with strongly desired properties and design flexibilities. In recent years, the development of new nanostructured materials has enabled an evolving shift from single purpose materials to multifunctional systems that can provide greater value than the base materials alone; these materials possess attributes beyond the basic strength and stiffness that typically drive the science and engineering of the material for structural systems. Structural materials can be designed to have integrated electrical, electromagnetic, flame resistance, regenerative ability and possibly other functionalities that work in synergy to provide advantages that reach beyond that of the sum of the individual capabilities. Materials of this kind have tremendous potential to impact future structural performance by reducing size, weight, cost, power consumption and complexity while improving efficiency, safety and versatility. Actually, also a very advanced design of an aircraft has to take required inspection intervals into account. An aircraft with inherent protective and smart abilities could help to significantly extend the inspection intervals, thereby increasing aircraft availability. The main objective of this EASN endorsed proposal is to develop and apply a multifunc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Effect of structure upon the reactivity of catalytic nanoparticles' (ESRCN).

assistant: **Concept**

Heterogeneous catalysis is an area where nanotechnology is present in people's everyday lives. Catalytic processes are found in diverse applications such as fuel-refining, the petrochemical industry, fertiliser production, automotive catalytic converters, biochemistry etc. They also provide a pathway to renewable, clean energy in the form of hydrogen fuel cell technology. Most modern catalysts take the form of catalytically active nanoparticles dispersed over some highly porous support medium. It is expected that the activity of these particles is largely determined by the density of catalytically active sites on the particle surface.  The proposed research will establish a new methodology in nanocatalyst research by using high-resolution experimental techniques to establish a close and unambiguous correlation between the morphology and reactivity of individual nanoparticles. The principal tools will be scanning tunneling microscopy (STM), which offers atomic-scale structural resolution, combined with scanning Auger microscopy (SAM), offering nanometer-scale chemical information. These techniques will be used to measure the surface structure and composition of catalytic nanoparticles before, after and perhaps even during a reaction and to correlate this data with the reactivity of the nanoparticles measured by temperature programmed desorption (TPD). By measuring the surface structure of individual nanoparticles it will then be possible to make a direct comparison with the results of computational modeling. This will open the possibility to optimize the nanoparticle size and shape in order to maximize the number of catalytically active surface sites, while minimizing the unused volume, thereby improving the efficiency of the catalyst while reducing the material cost.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Development of Biological Dosimetry systems for monitoring the impact of solar UVB radiation on the biosphere and human health'.

assistant: **Objectives**

It is the aim of the project, to develop and calibrate reliable field dosimetry systems for monitoring environmental UV radiation based on complementary biological UV dosimeters. The first objective is to characterise existing biological UV dosimeters according to a standard protocol. The second objective is to improve available biological UV dosimeters to better fulfil the requirements for field measurements of the biologically effective irradiance, Eeff, for different key targets. The third objective is to develop biological field dosimetry systems based on the most suitable and complementary biological dosimeters. Special attention will be placed upon the dosimetric quantity for Eeff which should be based on the SI system and allow comparison of predicted data with those that have been biologically determined. In field and laboratory intercomparison campaigns the biological dosimetry systems will be compared and calibrated with spectroradiometric-based measurements. Adaptations of the biological dosimetry systems for the special requirements of personal dosimetry, underwater dosimetry, and field measurements in deserts or high mountains will be developed. First field measurements will be conducted and standard protocols will be elaborated for the different field uses of the biological dosimetry systems.The biological dosimeters will be prepared, exposed and analysed according to standard biological and  dosimetric protocols. For their characterisation, action spectroscopy will be applied using monochromatic and  polychromatic UV-radiation. The quality of the biological dosimeters will be assessed during two field  intercomparisons in combination with spectroradiometers. Expected values, obtained from the multiplication of  the spectral data with the relevant action s