RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Collaborative and Sustainable Astronomical Data Infrastructure for Europe'.

assistant: **Concept**

The Collaborative and Sustainable Astronomical Data Infrastructure for Europe (CoSADIE) project will undertake actions aimed at designing a sustainable version of the already successful European Virtual Observatory (Euro-VO). The concept of a Virtual Observatory (VObs or VO) is that all the world's astronomical data should feel like they sit on the astronomer's desktop workspace, analysable with a user selected workbench of tools and made available through standard interfaces across the whole range of astronomical research topics. VObs is embraced as a world-wide community-based initiative with the potential to transform and restructure the way astronomy research is done. The European Virtual Observatory, Euro-VO, is the European implementation of this idea. The astronomical Virtual Observatory has been identified as one of the important infrastructures of astronomy in the recent European strategic exercise performed by the Astronet ERA-NET. The VObs is currently in transition towards operational phase. This proposal is centred on the development of strategies and coordination structures, through a feasibility study for a sustainable European Virtual Observatory giving access to the open, highly diverse, highly distributed data holdings of astronomy. It also aims at disseminating results among and gathering requirements from the scientific community (users) and the data providers. It will co-ordinate European technical activities, and includes the promotion and monitoring of international standards, and their adoption through the International Virtual Observatory Alliance. Co-operation and interface with the grid and cloud will also be assessed, with a particular consideration towards EGI.eu and OGF. Specific care will be taken to consolidate the high impact VObs outrea
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Controlling information flow in multi-layered neuronal networks' (CIFINE) under Seventh Framework.

assistant: **Objectives**

The neural representation of the physical world is an often deliberated concept whose concrete rules still elude our understanding. Behavioral responses must be generated from a myriad of different stimulus combinations, but it is still not clear which factors contribute to the brain’s ability to target small cell populations for distinctive stimuli, and reliably route a signal to its appropriate targets. Previous work has made considerable progress on the sub ject of stable propagation of temporally and rate encoded signals in neuronal networks. However, simple signal propagation does not suffice to explain cortical processing because at any given instant most stimuli are ignored, not propagated, and signal paths have to change dynamically with the task at hand. I have recently shown that rate encoded signals can be turned on or off by a mechanism called detailed balance, making it a very good candidate to control functional connectivity in neuronal networks. I want to implement this mechanism in large networks to unite or separate multiple simultaneous signal streams to filter and propagate task-specific information. The often talked-about cocktail party problem, in which a listener must gather a single multi-faceted signal from a rich and noisy background, is an intuitive example of such a task and should be generally solvable by the networks we will implement. The results will, for the first time, give rise to a canonical, generally applicable yet stimulus specific processing circuit in cortical networks. This will be of tremendous help for the experimentally complex task of observing real signal processing and provide for a platform for the discussion of dynamic cortical processing.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Tools and techniques for integration of workflow with GroupWare and business process reengineering'.

assistant: **Concept**

The objective of INSTRUMENTS is to investigate, design and develop a set of solutions to solve one of the key decisions that companies are facing today about their information systems support for their business processes and the usage and interaction among how to automate, in an optimum way, the cooperative process, that is, how to select and optimally use workflow systems, groupware environments and BPR decision support tools.The problem is present in most medium and large companies. Market movements, such as the acquisition of Lotus by IBM or the Information Exchange by Microsoft, the market studies about workflow growing, the tendency to distributed systems, etc., have led to an uncertain position for many companies who wish to decide on their information systems for their future business processes. The solutions developed in the project will be focused in being used by the market, and they include: - A methodology facilitating decisions concerning which information systems available in the market are optimum for the different aspects for the business process. It will facilitate decisions about when groupware tools or workflow systems should be used, constraints and factors to be taken into account, how to apply them, benefits expected, functionalities to be obtained, etc. The methodology will help to make decisions at the time of designing or reengineering the business processes, as a complementary means to facilitate natural evolution of the BPR process in later implementation. - A set of tools that will facilitate the transfer from the model, optimized and simulated by BPR tools, to the model used by workflow systems. This is one of the key issues for the usage of BPR tools and the workflow and groupware systems. This will eventually lead to a more integrated appr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Rhabdoviruses in wild marine fish in European coastal waters: characterisation and significance for aquaculture' (1994-1998) under Fourth Framework.

assistant: **Objectives**

The proposed research concerns the application of advanced biotechnology for solving a major fish health legislative problem concerning the recent finding of an important viral pathogen, VHS virus, in the marine environment and investigative scientific research on host pathogen relationships of marine VHS at the molecular level. Specific objectives are:I. To determine the distribution of VHS virus in selected stocks of wild fish species in the Eastern Atlantic, North Sea and Baltic Sea.II. To assess by experimental infection the virulence of marine isolates of VHS virus for aquaculture fish species of commercial significance including studies of disease pathogenesis.III. To identify genetic and/or antigenic differences between marine VHSV isolates and other VHSV isolates.IV. To identify genetic and/or antigenic differences between virulent and non-virulent VHSV isolates.STATE OF PROGRESSFor the first two years the results of 17 research vessel cruises are reported. A total of 46,046 fish were sampled (5,634 fish samples remaining to be tested in 1999) comprising 43 species. Numbers of virus isolations were 107 from 12 species namely herring 40; sprat 37; dab 7; cod 7; Norway pout 7; whiting 2; plaice 2; flounder 1; blue whiting 1; rockling 1; lesser argentine 1; poor cod 1. Isolates were from the south Baltic Sea, Skagerrak, Kattegat, south Norwegian coast and the Atlantic, north and west of Scotland. Four isolates were made from cod skin showing lesions, 1 from normal cod skin and the rest were made from internal organs of asymptomatic fish. Using all types of skin lesion material from cod for virus isolation it was shown no correlation existedVirulence testing of the marine isolates against rainbow trout: By bathing 32 isolates of European marine origin were tested in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'How a mutualism evolves: learning, coevolution, and their ecosystem consequences in human-honeyguide interactions'.

assistant: **Objectives**

Species interactions such as mutualism, parasitism and predation underpin much of life’s diversity. We aim to understand the mechanistic role of learnt traits in the origin and maintenance of mutualistic interactions between species, and to test their evolutionary and ecological consequences. To do so, we shall study a remarkable mutualism: the foraging partnership between an African bird species, the greater honeyguide Indicator indicator, and the human honey-hunters whom it guides to bees’ nests. Honeyguides know where bees’ nests are located and like to eat beeswax; humans have the ability to subdue the bees and open the nest, thus exposing beeswax for the honeyguides and honey for the humans. This model system gives us a wonderful opportunity to study mutualisms, because local human and honeyguide populations vary strikingly in whether and how they interact, and because we can readily manipulate these interactions experimentally. We have already demonstrated that it is fully feasible to carry out observational and experimental work at a study site we have established in cooperation with a honey-hunting community in northern Mozambique. Here, and at a series of comparative field sites we have identified in south-eastern Africa, we shall ask: is learning involved in maintaining a geographical mosaic of honeyguide adaptation to local human cultures? How does reciprocal communication between humans and honeyguides mediate their interactions? What are the effects of cultural co-extinctions on each partner and their ecosystems, and how quickly can such cultures be re-ignited following their loss? In so doing we shall test for the first time the hypothesis that reciprocal learning can give rise to matching cultural traits between interacting species. Understanding the role
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Enhancement of the life science interface group capabilities' (ELSIC), addressing dissemination and exploitation.

assistant: **Impact**

There is tremendous potential for development and use of innovative advanced ICT technologies at the interface between information technologies and other disciplines described collectively as life science research. These range from miniaturisation and non lab based versions of well known techniques to the development of new methods and tools allowing for example 'point of care' diagnostics and less invasive implants to be fabricated.This multi disciplinary research integrating life sciences is a growing area of research and merging the skills of ICT technologies and biotechnologies has been identified as an important growing area both for research and commercial developments, of high importance for Ireland by major new initiatives such as Science Foundation Ireland (www.sfi.ie). The Life Science Interface team is a multidisciplinary team in the Tyndall National Institute whose core interest lies in integrating life sciences with micro-electronic derived capabilities.The team is in its infancy and is looking to expand and learn new skills and techniques that will help establish their knowledge and research in this multidisciplinary area and also to establish collaborations with other institutes involved in this area. This will ultimately allow the life science interface team to develop and qualify underlying key technologies to enable interfacing to DNA, proteins and cells for in vitro and later for in vivo applications including the generation of biomedical devices.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Identifying targets of ring finger and scf complex e3 ligase proteins in the plant defence response'.

assistant: **Objectives**

Plant disease resistance (R) genes are key components in pathogen perception; R genes activate a battery of responses, and the recognition by R genes is hypothesized to be upstream of a signal transduction pathway. A cDNA-AFLP analysis resulted in the identification of ~ 150 Avr9/Cf-9 rapidly elicited (ACRE) genes. These ACRE genes became rapidly induced or repressed within 30' upon elicitation of a Cf-9 (R) tobacco cell culture. In addition to known signal transduction components ACRE genes code for putative components of the E3 ligase complexes, such as RING-H2 finger proteins, U box, and F box proteins components of the SCF complexes. E3 ligases complexes play a critical role in the selection of substrates for proteolysis. Selected substrates become 'tagged' with Ubiquitin, which targets them to the 26S proteasome. The specific substrates for each E3 ligase are expected to be negative regulators of the plant defense responses. The aim of this project will be to identify the substrates of the identified F-boxes, which seem to specifically recognise phosporylated substrates. Ubiquitination is a novel aspect in plant defense responses and it probablyplays a larger role in plants than in other organisms. Epitipe-tagged versions of the U boxes will facilitate in the identification of the putative interactors. Subsequently, an in-depth biochemical study will reconfirm the putative interactions. Finally, we will obtain a protein-protein interaction map for the identified E3 ligase complexes. The aim is to unravel the role of ubiquitination in plant defense responses. The proposed technique for the purification of protein complexes will require a substantial biochemical optimization to obtain intact E3 ligase protein complexes. Putative interactors will be identified by mass
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'South East Asia centre on European GNSS for international cooperation And Local development' to be submitted under Seventh Framework.

assistant: **Abstract**

The main objective of the project is the definition of an implementation plan for a European GNSS Collaboration Centre in support of educational, commercial and technical needs in South-East Asia that “will increasingly be one of the most dynamic growth engines of the world economy”. The plan for the creation of the Collaboration Centre foresees also accompanying awareness actions (2 workshops; Centre Opening Ceremony) to facilitate the start-up of the Centre and its visibility as well as to link it to European institutions in order to ease continuing cooperation and sustainability. The Collaboration Centre should be set up within this project and start its operation at the end of the project.Since limited resources do not allow to target all the South-East Asia Countries, and in order to ensure the highest chance of success to the action, the project deeply relays on the commitment, from the Asian side, of two Universities: HUT and AIT. HUT is the leading Vietnamese higher education technical institution with important ties with Ministries and Governmental Bodies as well with specific technical expertise and technical staff trained in GNSS. Therefore, HUT is the ideal recipient for the Cooperation Centre to which it can offer important local and regional links both technical and political. AIT is a well known international higher education institution based in Thailand, but addressing a truly international group of users. Its long lasting cooperation with HUT makes it an ideal partner to direct the actions of the Cooperation Centre also in the whole South-East Asia region.European partners have complementary expertise in important sectors of GNSS with consistent Research and Teaching experience, as the Master on Navigation at Politecnico di Torino, supported by the UN
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Sputtering matter onto storage plates for delayed quantitative investigations, against fraud, of organic and inorganic samples' (1998-2002), addressing dissemination and exploitation.

assistant: **Impact**

This project suggest to develop a new instrument (the Sputtering Storing Matter Instrument, SSMI) and use existing SIMS and XPS instruments for organic and inorganic applications:- organic: the deposition of molecules on Silver substrates in the SSMI will increase the ionisation efficiency of the rnolecules by a factor of 100-1000 Molecules (licit and illicit drugs not yet detectable will be investigated).- inorganic: by diluting the atoms on a clean/reproducible substrate in the SSMI, quantification of complex, layered, materials will be possible and detection limits in the ppm range are achievable.This will allow characterization of surfaces or coatings and hence permit to secure patents and contribute to the fight against fraud.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Antimicrobials by immune stimulation' in the context of a Sixth Framework call.

assistant: **Objectives**

The tremendous success with which antibiotics have been used to combat infectious diseases is under serious threat from the increasing development of antimicrobial resistance. Without new treatment approaches to address antimicrobial resistance, this threa t will continue to rise. To fight infectious diseases effectively in the future we have to broaden the approaches in therapeutic intervention. There are three ways along which the therapeutic intervention of infectious diseases can be broadened. The first is to design drugs that have a smaller chance for resistance-development (to target evolutionary conserved structures is one key element here). The second is to design drugs that are as different in mechanism of action as we can envision. The third is to c ombine drugs. AMIS (Antimicrobials by Immune Stimulation) combines these three strategies in a highly innovative approach. AMIS aims to use the strength of our own innate immune system to design antimicrobial drugs for future generations. Antimicrobial pr oteins in our immune system are often combined with inflammatory signals in one single molecule. AMIS will take that same approach and reshuffle different parts of different molecules to make novel effector molecules that still have these combined function s but are optimally adapted for therapeutic intervention. Within our innate immune system many molecules have been identified over the last years that are involved in direct or indirect clearance of bacteria. The consortium will select the most promising and innovative compounds with this dual mode of action and: - Design proteins with anti-microbial activity in combination with an inflammatory trigger, targeting extra cellular bacteria; - Design proteins with inflammatory priming capacity (without extra anti-mi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Titan's Lakes: Croll-Milankovitch, Seasonal and Hydrologic Cycles' under Seventh Framework.

assistant: **Concept**

A set of liquid hydrocarbon lakes and lake basins has been discovered in Titan's high latitudes. The lakes exhibit a dramatic hemispheric asymmetry; significant area fractions of the northern high latitudes are covered by lakes, while the same southern latitudes are largely devoid of such features. We consider the hypothesis and its consequences that in addition to known seasonal changes, the observed difference in lake distribution may be caused by an asymmetry in the seasons owing to the orbit. Due to Saturn's eccentricity, the instantaneous solar insolation received at Titan is asymmetric. The asymmetry drives a hemispheric difference in evaporation minus precipitation, and hence, in the accumulation of lakes on Titan's northern and southern surfaces. The effect is modulated by, and reverses with, dynamical variations in the orbit. In this picture, much like in Earth's climate and glacial cycles, the resulting vigorous hydrologic cycle has a period of tens of thousands of years. We seek to answer the following fundamental questions:1. To what extent do Titan's varying orbital parameters control the long-term volatile transport and surface reservoirs?2. How do Titan's lakes and seas respond to seasonal forcing?3. What is the relative role of subsurface transport of methane and ethane?4. What constraints and general properties may be derived in order to better understand Titan's overall climatologic and hydrologic evolution?