RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'SENSITIVE TECHNOLOGIES AND EUROPEAN PUBLIC ETHICS'.

assistant: **Objectives**

This proposal is to establish a Consortium to provide academic input into the planned Eurobarometer Survey on the Life Sciences and Sensitive Technologies in 2008. It is also intended to add value to the survey and thereby enhance its impact and policy relevance with extensions of a conceptual, contextual and a methodological nature. First, we introduce the concept ‘public ethics’, moving beyond public perceptions to acknowledge that ideas of equity, nature, and responsibility contribute to the public’s assessment of technological innovation. Second, and to maximize policy relevant, the survey findings will be interpreted in the context of national policies on technological innovation and the ways in which national initiatives have, or have not, taken account of public ethics. Third, the consortium will develop tools for valid cross national comparisons, going beyond much current research that merely compares means differences and percentages. Better tools for such comparisons will make it possible to extract much more relevant information from survey research. The EB survey in 2008 will be the seventh in a triennial series that has run since 1991. The EB surveys on Biotechnology are internationally recognised as an authoritative, systematic and dispassionate assessment of the contours of public opinion. The data from these surveys provide both contemporary insights into public perceptions about sensitive technologies and time series data on the evolution and change in public opinion. The past surveys have made important contributions to the informed debates on many developments in biotechnology, most recently seen in a contribution to the European Parliament’s decision on human embryonic stem cell research in 2005. The understanding of the role of public ethics in rela
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Biological Factors in Fleas: Determinants of Physiology and Pathogen Transmission' (FACTORS) targeting Horizon Europe.

assistant: **Abstract**

Vector-borne diseases are caused by pathogens transmitted by hematophagous arthropods (vectors) and affect millions of people worldwide. The rat flea, Xenopsylla cheopis, is a major vector for several pathogens, including Yersinia pestis, the causative agent of bubonic plague. Despite periodic outbreaks of this and other flea-borne diseases, research on flea biology remains neglected. Understanding the biological processes underlying flea physiology and their ability to transmit human pathogens is crucial for comprehending the dynamics of flea-borne diseases and implementing sustainable control strategies. This project aims to uncover the biological FACTORS in fleas that contribute to pathogen transmission, with a specific focus on the plague agent.Under identical experimental conditions, different rat flea strains exhibit variations in blood feeding, colony development, and Y. pestis infection, leading to the hypothesis that strain-specific biological factors in fleas impact their physiology and the transmission of the plague agent. Through comparative studies between flea strains from regions with high or low plague prevalence, FACTORS aims to uncover the role of (1) genes expressed in the gut, (2) flea-associated microbiota, and (3) immune cells in flea feeding, development, and Y. pestis infection, all of which dictate pathogen transmission.FACTORS will address a largely neglected area of flea biology, generating profound insights into the biological processes contributing to the dynamics of plague, while also identifying new targets for the development of innovative vector control strategies. This aligns with the UN Sustainable Development Goal of promoting health and well-being. Additionally, the training in soft skills, expanded networks, and the excellence of sc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Killer plasmids as drivers of genetic code changes during yeast evolution'.

assistant: **Concept**

The genetic code was established at a very early stage during the evolution of life on Earth and is nearly universal. In eukaryotic nuclear genes, the only known examples of a sense codon that underwent an evolutionary change of meaning, from one amino acid to another, occur in yeast species. The codon CUG is translated as Leu in the universal genetic code, but it has long been known to be translated as Ser in some Candida species. In recent work, we discovered that this switch is one of three parallel reassignments of CUG that occurred in three closely related clades of yeasts. CUG was reassigned once from Leu to Ala, and twice from Leu to Ser, in three separate events. The meaning of sense codons in the nuclear genetic code has otherwise remained completely stable during all of eukaryotic evolution, so why was CUG so unstable in yeasts? CODEKILLER will test a radical new hypothesis that the genetic code changes were caused by a killer toxin that specifically attacked the tRNA that translated CUG as Leu. The hypothesis implies that the reassignments of CUG were not driven by selection in favor of their effects on the proteome, as commonly assumed, but by selection against the existence of a particular tRNA. As well as searching for this killer toxin, we will study the detailed mechanism of genetic code change by engineering a reversal of a CUG-Ser species back to CUG-Leu translation, and investigate translation in some species that naturally contain both tRNA-Leu and tRNA-Ser molecules capable of decoding CUG.


**Keywords:** tRNAs,  selfish genetic elements,  genetic code,  translation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Cutting of food products by ultrasounds' (1994-1998).

assistant: **Concept**

Food products are more and more proposed to the consumers already cut. Many technologies are used like cutting with skip-tooth saw blade, laser cutting or high pressure water cutting. But, all of these technologies present many inconveniences and more particularly when products are soft, sticky, crumbly, heterogeneous, such as: high level of raw material losses (sometimes near of 6%), bacteriological contamination of one product by another one, food products are sometimes burnt (laser cutting), they don't propose safety guarantee for working personnel. Cutting products by ultrasound is a new technology which can solve all of these problems. It is able to cut very small portion of soft products with no contamination and no danger for workers. Commercial opportunities are very large and the proposers have already identified many companies (bakery, pastry industry, pastry cooked delicatessen,...) which are interested in developing such technology. Some trials have been made in laboratory and are very optimistic.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Dynamics and stability of ionization waves in an external electric field' (1994-1998).

assistant: **Innovation**

Research objectives and content The objectives of this research is to investigate theoretically the time evolution and stability of ionization waves (IW) that propagate in an external electric field and result in electrical breakdown of gases. The planar IW will be considered within the framework of the system of equations containing the rate equations for electrons and ions taking account of the Townsend mechanism of ionization and the Poisson equation for the self -consistent electric field. For 1D case this system can be reduced to the first-order nonlinear partial differential equation for the electric field, which can be solved analytically for some particular dependencies of the ionization frequency on the local electric field and numerically in the general case. These tools will allow the investigation of the interactions of various IW and the events resulted from the collisions of two IW. For stationary moving planar IW the analysis of their stability will be carried out on the basis of the dispersion equation for the complex eigenfrequencies which will be obtained for the linearized system of partial differential equations describing small 2D perturbations superimposed on nonlinear 1D solutions respresenting stationary moving IW. Both asymptotic and numerical methods will be employed for studying the stability. This analysis is intended for explanation of instabilities of the IW and streamers observed in discharge gaps with planar electrode walls. Training content (objective, benefit and expected impact) This scientific visit will extend the knowledge of the scientific group at the Physics Department of the University of Madeira supervised by Prof. Benilov in the field of kinetics of non-equilibrium plasma. physics of gaseous discharge and the general theory of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Mapping of research in european social sciences and humanities'.

assistant: **Objectives**

MORESS aims to support the development of the European Research Area through improving information on pan-European research in social sciences and humanities. The extensive geographical coverage available to the European University Association through its individual and collective members (higher education institutions and rectors conferences ) will be exploited to catalogue and build links between existing national information sources, and to expand the information base on a restricted number of themes. Two objectives will guide the project : (1) to improve the accessibility and use of information sources across Europe through developing innovative means of linking nationally available data sources, and (2) to expand the information base in a small number of pluridisciplinary areas in response to specific public policy challenges. MORESS thus has the objective of making a significant contribution to promoting European social science research.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Development of new environment friendly industrial ceramics' (1998-2002), addressing dissemination and exploitation.

assistant: **Impact**

Materials science knowledge and preliminary laboratory tests revealed that a ceramic like material, mullite, can be produced by solid state transformation under the effect of pressure, temperature and time silica (from slate powder) reacting with alumina produced by thermal decomposition of aluminum hydroxide (major constituent of aluminum sludges) The main general objective of this project is to produce a new industrial ceramic material using aluminum sludges from anodizing industries and slate powders from slate quarries and transformers as raw materials. Different types of products will be investigated with improved performances, like roofing and flooring tiles (using the high surface adherence observed) to high resistance technical components, in a clear multisectoral application for products.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Nonlinear magneto-optical studies of thin magnetic films' in the context of a Fourth Framework call.

assistant: **Objectives**

We propose to study the properties of magnetic (multilayer) films using the recently discovered technique of Magnetisation-induced Second-Harmonic Generation (MSHG). This nonlinear Magneto-Optical Kerr Effect (MOKE) is not only interface specific but is 10 3 times larger compared to its linear counterpart. Magnetic multilayers show exciting new properties like Giant Magneto Resistance and Quantum Well States, which have a large potential for practical applications. The interfaces between the various metallic films play an important role in these systems. Unfortunately, the buried interfaces are experimentally very difficult to investigate by standard magnetic probes. By comparing both the nonlinear (interface) and lin- ear (bulk) MOKE signals, one shall be able to discriminate between bulk and interface contributions to the magnetic properties of the thin multilayer films. We want to particularly investigate the (Magnetic) Quantum Well States as recent experiments have shown that MSHG is an extremely effective technique for this purpose.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Development of quantum computer hardware based on rare-earth-ion-doped inorganic crystals' (1998-2002) under Fifth Framework.

assistant: **Objectives**

We propose to experimentally demonstrate that reliable quantum computer (QC) hardware can be built with rare-earth-ion-doped inorganic crystals (RE crystals). We claim that RE crystals at liquid helium temperatures have exceptionally favourable properties as quantum computer hardware and present a scheme for controlled logic and quantum computations in liquid helium cooled RE crystals. Specifically we wish to use RE crystals to successfully demonstrate initial steps towards performing the first CONTROL-NOT quantum gate in a solid-state material.Our intention with this FET-Open assessment project proposal is to demonstrate that the proposed scheme works and thereby establish RE crystals as a highly competitive candidate for quantum hardware. When this has been done we foresee the formation of a large-scale project with participating groups in theory, material science and laser development to develop more versatile QC hardware based on RE crystals.We propose to experimentally demonstrate that reliable quantum computer (QC) hardware can be built with rare-earth-ion-doped inorganic crystals (RE crystals). We claim that RE crystals at liquid helium temperatures have exceptionally favourable properties as quantum computer hardware and present a scheme for controlled logic and quantum computations in liquid helium cooled RE crystals. Specifically we wish to use RE crystals to successfully demonstrate initial steps towards performing the first CONTROL-NOT quantum gate in a solid-state material.Our intention with this FET-Open assessment project proposal is to demonstrate that the proposed scheme works and thereby establish RE crystals as a highly competitive candidate for quantum hardware. When this has been done we foresee the formation of a large-scale project with participat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Eldercare Policy Implications on the Time Use Patterns and Quality of Life of the Elderly and Elder Caregivers in Europe, UK, US, and Japan', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The demographic trends in the ageing population suggest that the elderly will represent a substantial proportion of the population in most industrialised societies within the next 50 years. These trends indicate that countries will have to face tough social welfare decisions to make regarding the development of further strategies on how to ensure safe and dignified ageing of its growing population of the elderly. Many countries introduce a variety of strategies in their policies of support and quality of life for their elderly. There is a range of long-term care policies as well as formal care provision services available in the industrialised countries. However, the efficacy and sustainability of these strategies remain unclear. This research will analyse the effects of different policies and elderly care strategies in the select European, North American, and East Asian countries, focusing on the UK, US, and Japan. Using sequence analysis, multiple correspondence analysis, and multilevel models with access to supercomputer facilities at the University of Oxford, I plan to define the main typologies arising in the different countries, the effects of long-term care policy interventions and formal care services in these countries, and the demographic and resource-based antecedents of why such patterns and typologies arise. I will also analyse the strain in paid and unpaid work among elder caregivers as the result of different policy trajectories, as well as the effects on gender equality of the political choices. I have access to 6 different datasets to analyse for this project: ELSA (UK), UKTUS (UK), HRS (USA), ATUS (US), SHARE (Europe), and MTUS (Europe). The project will result in at least two peer-reviewed journal articles, two reports published as discussion papers,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Multidisciplinary Training in Chronic Kidney Disease: from genetic modifiers to drug discovery', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Chronic kidney disease (CKD) is recognized as an increasing global health problem. It currently affects 10-15% of the worldwide population, is associated with impaired quality of life and reduced life expectancy, and represents a significant burden for health care budgets.CKD is characterized by the progressive decline of renal function. Little is known about the mechanisms underlying this progression and the genetic factors that predispose patients to different rate of progression. Even worse, there is no reliable biomarkers capable to identify patients at risk of fast progression and treatments able to halt CKD progression.Understanding the physiopathology of CKD is therefore a prerequisite for the development of efficient preventive strategies and diagnostic tools.With this goal in mind, TrainCKDis will provide an innovative, multidisciplinary, and intersectoral training programme, able to prepare top-level young scientists to develop creative solutions for CKD. The proposed 15 research projects will address key challenges: i) the identification of genetic and epigenetic modifiers that predispose patients to CKD progression, ii) the identification of pathways and biomarkers for monitoring CKD progression and iii) the identification of novel therapeutic targets to improve the limited treatments for CKD.TrainCKDis gathers top European laboratories, companies, hospitals, and associations involved in the treatment of CKD.Early Stage Researchers (ESRs) will thus benefit from an outstanding interdisciplinary platform integrating nephrology, epidemiology, genetics, cell biology, high-throughput screening, system biology, and metabolomics experts, as well as experimental animal models and unique human biobanks. Moreover, ESRs will be trained in disseminating results through