RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Climate change and migration narratives through culture and policy'.

assistant: **Innovation**

This project examines two key aspects of the international discourse on climate change and migration: culture and policy. This discourse has become increasingly urgent during the 21st century as governments, institutions and the media fiercely debate climate change on the one hand and migration and borders on the other. Dominated by the Global North, the discourse has promoted alarmist assertions of climate change and migration as inextricably connected and destined to provoke conflict and scarcity, assertions often underpinned by a racialised military-security rhetoric. This discourse also routinely overlooks the real economic, political and social needs of those most affected by climate change and the discriminatory mobility regimes that govern them. To date research on the role played by narrative has been limited, nor have the intersections between culture and policy been studied. Recognising that climate change and migration are made known through different forms of narration and storytelling, through which certain interpretations or potential policy responses are favoured while others are discounted, CLIMINAR addresses the following question:What role do cultural and institutional narratives play in either challenging or upholding the dominant alarmist discourse on climate change and migration?The overarching research objectives are to: (1) analyse cultural narratives, in particular fiction and film; (2) examine institutional narratives, specifically policy material produced by NGOs and international governmental organisations, as forms of culture; and (3) comparatively assess all texts by developing and implementing a methodology that ascertains the ethical dimensions of narrative and its ability to incorporate both climate justice and mobility justice. This inte
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Atmospheric Exchange of Persistent Chemicals in Bothnian Bay, Northern Baltic Sea'.

assistant: **Innovation**

Atmospheric deposition and air-sea exchange of persistent chemicals in Bothnian Bay are investigated with goals of understanding current atmospheric loadings and how future loadings will respond to changes in ice cover and air concentrations. Substances examined are organochlorine pesticides (OCPs), current-use pesticides (CUPs) and brominated flame retardants (BFRs), substances which have been shown to undergo long-range transport and deposition in the Arctic and other remote locations. The CUP endosulfan and the BFRs polybrominated diphenyl ethers (PBDEs) are listed among the eight “hazardous substances of specific concern to the Baltic Sea” by the Helsinki Commission (HELCOM). PBDEs were recently added to the Stockholm Convention, and endosulfan and trifluralin are candidate substances. Concentrations of target chemicals are measured in air, Bay water, Bay snowpack, and rain. Seasonal and annual atmospheric loadings to the Bay are estimated from: a) air-water gas exchange, b) winter deposition in the snowpack, and c) rain deposition. Chemical “markers” (enantiomers of chiral compounds, natural bromoanisoles) are employed to trace air-water gas exchange, with emphasis on the effects of ice cover loss and the spring phytoplankton bloom. Enantiomer proportions are also used to follow microbially mediated diagenesis of chiral chemicals in water and soils. The project brings benefits to Sweden and the European community by making the first atmospheric deposition estimates for these substances in the northern Baltic, providing the first data on two HELCOM hazardous substances in Bay air and water, complimenting air measurements made at European Monitoring and Evaluation Program (EMEP) stations in southern Sweden and arctic Finland, and linking with the EU project ARCRISK a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Opto-Biomechanical Eye Research Network' to be submitted under Horizon 2020.

assistant: **Abstract**

The eye is a biological tissue with optical and biomedical properties that govern the way the eye refracts light, focuses thatlight onto the retina and can dynamically alter that focus over a range of distances. This impressive flexibility results from thedelicate way in which the mechanical properties of the eye very precisely affect its optics. These properties varyconsiderably between individuals and can alter over time in response to visual demands, as well as with eye growth, ageingand pathology. The origins of these biomechanical changes over time are very poorly understood, however, and point at aneed for answers, given the increase in life expectancy and in societal demands for high quality vision. To address theseissues, we present the first European collaboration that brings together a group of scientists that work on the optics andbiomechanics of the eye, cover a broad range of disciplines and skills. This highly interdisciplinary consortium will alsocreate a training network to give young researchers the opportunity to learn from renowned experts on ocular optomechanics,share their learning experiences and take advantage of placements in Universities, hospitals and industry. Thiswill give them a wide and novel skill set to translate their research to scientific, industrial, or clinical applications, such as anew generation intraocular implants for cataract surgery, biologically relevant eye models that mimic the eye at any age, andnovel treatment therapies that can control, reduce or ultimately prevent refractive error from occurring. These anticipatedinnovations will lead to wide-reaching and pioneering advances to enhance our understanding of the interrelationshipbetween ocular optics and biomechanics. From this, the young researchers will emerge with mult
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Hyperaccumulator-grass-derived Antibacterial Boron-functionalized Carbon Dots: Synthesis and Cytotoxicological Evaluation' to be submitted under Horizon Europe.

assistant: **Abstract**

The antibiotics’ overuse exerts selective evolutionary pressure on microbial pathogens, leading to the emergence of resistant strains. To reduce the likelihood of future epi/pandemics of bacterial origin, it is, thus, essential to put alternatives in action and consume antibiotics more sparingly. While the heavy metal-based antimicrobial agents are convenient for some uses, they bring human and environmental toxicity issues and suffer from microbial resistance. With their potentially low risk of resistance development, carbon-based nanomaterials seem like promising substitutes. Carbon dots (CDs) are particularly interesting owing to their small size, good solubility, and relative affordability, and boron-doped CDs (BCDs) deserve even greater attention as they typically show high antimicrobial activity. However, our current understanding of the toxicity profile of BCDs is fragmented and limited to materials synthesized by small molecular synthetic precursors as carbon and boron sources. In the project HyperABCD, we will first show the hydrothermal conversion of a boron-hyperaccumulator plant (biomass) into BCDs. Then, we will explore the antibacterial activity of BCDs on Gram-negative and Gram-positive species using various bacterial susceptibility tests. Next, we will undertake toxicological evaluations at different levels. To this end, we will perform standard viability tests with various human cell lines as well as a mutagenicity test. The assembled research team is fully competent to realize the ambitious goals of the proposed cross-European effort. I am a multidisciplinary researcher specializing in antimicrobial nanocarbons. The primary host (Dr. Alberto Bianco, CNRS, Institute of Molecular and Cell Biology) is among the pioneers of biomedical nanocarbon research,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Bioactive materials for enhanced preventative and restorative dental solutions' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

This project proposes three PhD studies to address the problems of (i) Caries and (ii) enamel erosion by acidic foods (leading to sensitive teeth). In both cases, encouraging re-mineralisation (the formation of new calcium phosphate) can help avoid these problems. Where restorative work is required, re-mineralisation has potential to enhance the lifetime of restorations and so further reduce the number of visits to dentists. The PhD studies will represent a big challenge to the students selected, since knowledge of both materials chemistry and biology will be required. It is proposed that the students will spend 18 months at LUCIDEON developing novel powder materials in three generic areas:bioglass, sol-gel, and ceramics. In all cases, compositions will be based on calcium and phosphate, since it is release of these elements over time that will assist re-mineralisation. During the second half of their PhDs at the University of Lyon (UCBL), the students will assess the performance of these powders (both mechanically and biologically) is in specific formulations (for example as part of a novel glass-ionomer cement restoration).It is accepted that the nominal 18 months at LUCIDEON and 18 months at UCBL may, in reality, feature iterations in which (for example) an initial 6 months at LUCIDEON is followed by a period at UCBL to check for cytotoxicity or powder compatibility in composites.The success of the collaboration will depend on strong day-to- day mentoring by technical experts, attendance at seminars covering powder processing, in-vitro testing and biological testing) and the material devices regulation, as well as students gaining an appreciation of the practicalities of material supply and dentistry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Biobased food packaging quality assurance and food safety' (1994-1998).

assistant: **Innovation**

The biopolymer market is emerging fast and is anticipated to grow rapidly within the next ten years. Commercialization has been devoted mainly to short duration applications like disposables and waste bags. Little attention has been devoted to biopackaging of food products, irrespective of the fact that food packaging might entail a wide range of new business opportunities based on consumers demands for non-synthetic packaging materials. An understanding of the interactions between foods and packaging materials is essential to ensure optimal quality of food products. Consequently, development of the optimal food packaging materials demands contributions both from food scientists and polymer chemists. Based on a collaboration between scientists with different backgrounds, this Concerted Action will contribute to form a clear picture of the state of the art of manufacturing and application of biobased food packaging, defining the prospects for European biobased food packaging and future research needs.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Isolation of regulatory genes of alkaloid biosynthesis in cataranthus roseus.' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

Our objective is to isolate regulatory genes of the TIA biosynthesis via T-DNA tagging. Some tagged-lines have been isolated for their resistance to 4mT and high mRNA level of TDC and STRL. We propose to analyse T-DNA flanking sequences from this lines and from newly generated tagged lines.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'European Paediatric Oncology Off-Patent Medicines Consortium', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Cancer chemotherapy has a key role in the successful treatment of a number of childhood cancers. Nevertheless, at least 20% of patients are not cured by current therapies and a significant number experience debilitating toxicities. Given the high cure rates and potential life-span of survivors of childhood cancer, it is particularly important to minimize the impact of potential chronic toxicities. For several of the most widely-used drugs, little is known about their pharmacokinetics and metabolism in children, particularly very young children (<3 years). There are many examples where such knowledge has been used to optimize the use of chemotherapeutic drugs, both to avoid toxicity and to maximize the therapeutic effect. The need for further research to investigate these drugs in children is acknowledged in the Priority List for Studies into Paediatric Medicinal Products, issued by the EMEA. Doxorubicin is on this list and is one of the most important drugs used in the treatment of childhood cancers. Several national groups have been successful in studying the pharmacology of drugs used in paediatric oncology. However, in order to recruit sufficient patient numbers for meaningful studies it is necessary to establish a wider group, bringing together the successful elements of established national organizations. The EPOC group combines leading pharmacologists, paediatric oncologists, regulatory organizations and a management structure which will successfully deliver data of appropriate quality on which to base future clinical use of this drug and to meet the demands of the EMEA priority list. Such data will form the basis of future applications for Paediatric Usage Marketing Authorization for doxorubicin. The overall aim of the consortium is to provide data that will guid
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'From wrecks of ancient life to natural laboratories: Cave organisms as a testing ground for studying repeatability and predictability in evolution.' in the context of a Horizon 2020 call.

assistant: **Objectives**

Predicting evolution is one of the major aims of evolutionary biologists. Convergent evolution—the independent outcome of similar traits in distinct lineages—occurs frequently in nature at every level of biological organization in distinct evolutionary lineages. In this context, convergence has been considered to play contrasting roles in shaping biodiversity patterns. The success of colonizing and thriving in a new environment strongly depends on the existence, or lack, of specialized traits that ensure survival in it, a phenomenon referred to as environmental filtering. Thus, organisms adapted to extreme environmental conditions provide an ideal framework to study repeatability in evolution and, ultimately, to test for predictability, the ability to match a priori specialized traits to specific environmental conditions. Subterranean extreme environmental conditions exert strong selective pressure on strict cave-dwelling organisms which, respond by evolving a similar suit of phenotypic and physiological traits. The main aim of this project is to investigate whether environmental selective pressures, determine patterns of genomic convergent evolution in obligate cave-dwelling organisms. I will use an interdisciplinary approach, integrating field research, available ecological and phenotypic data, and newly generated genomic information to investigate the genomic bases of convergent evolution in cave-dwelling organisms. For this, I propose to investigate i) the genomic basis of adaptation to different subterranean microhabitats, ii) the speciation mechanisms in subterranean species, and iii) the causes of phylogenetic constrain on microhabitat preference. This project will give an unprecedented understanding of repeated evolution. Additionally, the results obtained may h
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Application of Solar Thermal Energy to Processes' in the context of a Horizon 2020 call.

assistant: **Objectives**

Application of Solar Thermal Energy to Processes (ASTEP) will create a new innovative Solar Heating for Industrial Processes (SHIP) concept focused on overcoming the current limitations of these systems. This solution is based on modular and flexible integration of two innovative designs for the solar collector (SunDial) and the Thermal Energy Storage (TES, based on Phase Change Materials, PCM) integrated via a control system which will allow flexible operation to maintain continuous service against the unpredictable nature of the solar source and partially during night operation. ASTEP will demonstrate its capability to cover a substantial part of the heat demand of the process industry at temperatures above 150 ºC and for latitudes where current designs are not able to supply it. Its modularity and compactness will also enable easy installation and repair with reduced space requirements, while most of components can be sourced locally. The ASTEP`s process integration will allow full compatibility with the existing systems of potential end-users of SHIP. These aspects will provide a very competitive solution to substitute fossil fuel consumption. The developed solar concept will be tested at two industrial sites to prove the objective’s target of TRL5. Life Cycle Analysis will be included to validate and demonstrate the efficiency of the proposed technologies. The first Industrial Site of the proposal is the world’s leading steel company, ArcelorMittal, with a heating demand above 220 ºC for a factory located at a latitude of 47.1 N (Iasi, Romania). The second site is the dairy company MANDREKAS, located at a latitude of 37.93 N (Corinth, Greece) with a heating demand for steam at 175 ºC and a cooling demand at 5 ºC. These test locations will validate the ASTEP solutio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Synthetic Molecules that Walk Down Tracks: The First Small-Molecule Linear Motors'.

assistant: **Concept**

The goal of this research project is to make the first synthetic small-molecule structures that can walk down tracks, mimicking the types of movement exhibited by the biological motor proteins myosin, kinesin and dynein. We propose to construct the first synthetic, mechanically processive, chemical systems from first principles; i.e. to design, synthesize, operate and characterize wholly synthetic small molecule structures that progressively advance directionally along a molecular  track  in response to stimuli. Different principles ( passing leg  and  inchworm  mechanisms) for processive mechanical molecular-level motion will be developed and experimentally explored. With some designs it is envisaged that the  walker  units will be able to change direction or switch between pathways as a result of external signaling or the nature of the environment and, ultimately, be able to transport a cargo from one place to another on a surface.  Sequential processive movement is unprecedented for wholly synthetic molecular structures and is the key requirement for making translational/linear motors that can perform tasks (transport cargoes from place to place or progressively exert a force) at the molecular level. Its successful demonstration would be a landmark accomplishment and mark a major new direction for synthetic supramolecular chemistry and molecular nanotechnology.