RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Building and improving support for RTD policy and public spending' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

The project has as a general goal to build a methodological framework and a learning platform for regional and national RTD policy makers and stakeholders interested in obtaining support arguments for their requests to bring public research spending to the Barcelona target level.In order to develop these tools, the consortium will:- identify and evaluate existing RTD funding models, policies and instruments in participating regions/countries including their communication- identify critical success factors for RTD funding policies resulting in enhanced research and innovation performance- select and present good practice cases assisting policy makers through mutual learning and benchmarking- formulate guidelines for successful target-oriented RTD funding policies and their implementation- offer recommendations to RTD policy makers on communication tools for obtaining funding levels necessary for _competitiveness-minded_ research, leading to new and improved products and services.Continuity of this project is also one of the main objectives of this proposal. It is proposed that the methodology and indicators used to measure the success of RTD funding policies and their communication should be continued, conducting periodical updates of the Regional RTD Policy Scoreboard. The audit process proposed can in the future include additional Member States, to get a larger scope of experiences and to further enable benchmarking and transferability of good practices across other EU Member States.It is also envisioned that the Project Advisory Group (including external auditors), which will be actively involved in contributing to the BIS-RTD project, continues its function after the termination of this project in the capacity of a public RTD funding observatory.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Blood-brain barrier junctions as targets for paracellular drug delivery to the brain' under Seventh Framework.

assistant: **Concept**

To maintain homeostasis of the central nervous system (CNS) the blood-brain barrier (BBB) prevents the free transcellular passage of hydrophilic molecules from the blood into the CNS. Because of this, the BBB is now recognised as the major obstacle to the treatment of most neurological disorders, as it hinders the delivery of many potentially important therapeutic and diagnostic substances to the CNS. Previous approaches in improving drug delivery across the BBB, which have primarily aimed at highjacking the transcellular transport machinery that is dedicated to the selective transport of specific molecules across the BBB, have had limited success, especially with regard to large molecular weight drugs. Lack of knowledge on the molecular composition and function of cerebrovascular cell-to-cell junctions has hampered the development of safe strategies for paracellular drug delivery across the BBB until recently. Members of the JUSTBRAIN consortium have accumulated knowledge on the structure and function of BBB cell-to-cell junctions, identified endothelial signals controlling the expression of individual junctional proteins and have begun to develop approaches, which may either open or close BBB junctions. Using in vitro and in vivo BBB models and animal models of neurological disorders, where BBB opening may be therapeutic, JUSTBRAIN is dedicated to translate this basic knowledge into identifying an entire novel platform of drugable molecular targets that could be functionally modulated thus allowing to bypass the BBB via the paracellular route. By these means JUSTBRAIN expects to improve efficient delivery of large molecules into the CNS and thus to expand on diagnostic and therapeutic possibilities for neurological disorders.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Plastics fate and effects in the human body' (PlasticsFatE).

assistant: **Concept**

The main goal of PlasticsFatE (Plastics Fate and Effects in the Human Body) is to improve our present understanding of the impact of micro- and nano-plastics (MP/NP) and associated additives/adsorbed contaminants (A/C) in the human body. Human exposure to MP/NP may result from the widespread use of plastic products and their release to the environment, where they degrade to MP/NP particles. But plastics particles reach natural systems also as secondary by-products, e.g., from tyre wear or abrasion of textiles. As a consequence, these particles are found in food, drinking water, air and environmental media (food chain, soils). Despite recent efforts to assess the real dimension of human risks associated with MP/NP, our current knowledge is still insufficient. One of the reasons is the lack of reliable and validated methods that are able to generate the science-based data we need. PlasticsFatE will address this challenge and associated uncertainties by implementing a comprehensive measurement and testing program (""test the test""), including inter-laboratory studies, to improve and validate the performance and applicability of available methods and tools to MP/NP. The tested and validated approaches will be used to (1) identify and detect MP/NP and A/C in a variety of complex matrices, such as food (vegetables, fruits, beverages, fish etc.), human tissues and consumer products (tooth paste, beauty products), as well as relevant environmental media (air, drinking water, soils), and to (2) assess their (also long-term) fate and toxicity in the human body by using advanced cell culture and organ models that simulate real exposure to MP/NP in the respiratory and gastro-intestinal tract. The newly developed innovative approaches will be integrated into a novel risk assessment
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Global change and pine processionary moth: a new challenge for integrated pest management' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The pine procession moth (Thaumetopoea pityocampa) is considered among the most important limiting factors for both growth and survival of pine forests in southern Europe and Mediterranean countries. In recent years the species has shown a tendency to expand its range to upper latitude and elevation, probably as a consequence of the global warming effect. In this context it seems necessary to reconsider the pest management strategies, because methods traditionally used in core areas need to be assessed before they can be applied in expansion areas. The new Integrated Pest Management will include:1. The assessment of the risk of outbreaks in new regions by a temperature-based model.2. The study of the genetic structure of populations in core and expansion areas.3. The identification of chemical signals active in host attraction/repellence.4. The assessment of bio-control extension from core to expansion areas.5. A cost-benefit analysis in core and expansion areas.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Enhanced Biomass Valorisation by Engineering of Polyoxometalate Catalysts' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

This project builds on a recent and ground-breaking discovery of the PI in the field of homogeneously catalysed, selective biomass valorisation. Materials technologies that promise improved catalytic performance are of utmost interest for a more sustainable chemical industry. Manipulating molecular catalysts like polyoxometalates (POM) in solution by tuning the solvent properties and gas atmospheres introduces a new paradigm in homogeneous-catalysed biomass valorisation technologies.It has been found that by using methanol as a (co)solvent, POM catalysts can completely suppress undesired total oxidation to CO2 under oxidative conditions. This drastically enhances the carbon efficiency from biomass to close to 100% yield. Remarkably, this manipulating effect could be explained with the formation of a new vanadyl-methanolate-complex in methanol-aqueous solutions having a methanol content of at least 10%.The proposed BioValCat project aims for developing this potentially disruptive technology towards an industrial viable biomass valorisation process by laying the foundations for a scalable, safe and economic process for the oxidation of biomass to valuable carboxylic acid esters. The project is structured according to the key challenges that have to be mastered in order to achieve this ambitious goal: a) Investigations to identify the nature of the POM-solvent interactions; b) Understanding and revealing the key organic mechanisms in solution; c) Development of novel POM catalysts specifically optimised to perform in aqueous-alcoholic solvent mixtures; d) Extension of the substrate and product scope to industrially viable biomass feedstock; e) Process development, with special emphasis on safety aspects, process intensification as well as product isolation and catalyst rec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Integrated and united? a quest for citizenship in an 'ever closer Europe'', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

The major aim of this research is to study the changes in the scope, nature and characteristics of citizenship presently underway as an effect of the process of deepening and enlargement of the European Union. It will focus on how integration and decentral ization processes, at both the national and European level, are affecting three major dimensions of citizenship: identity, representation, and practice of good governance. In a moment in which the EU is facing an important number of challenges, and given t hat its legitimacy and democratic capacities are questioned, it is important to address the issue of if and how is EU citizenship emerging. From this primary question stem three further sets of questions that will be the building-blocks of this research: ( 1) How does a particular kind of political structuring shapes citizenship? In a complex system, how do different identities coexist? (2) What sense of obligation is the EU citizenship developing? How do coexisting identities affect the relationship between elites and mass? (3) What are the citizens expecting from the EU as a level of government? To answer these questions, we will address the problems of citizenship under the threefold approach of identity, representation and evaluation of government perform ance, by looking at the dynamics between elites and public opinion, whose interactions traditionally nurture the dynamics of collective political identity, political legitimacy and representation, and standards of performance. A number of benefits and impa ct can be foreseen in this project. (1) A contribution to both, the empirical testing of existing theories of integration and citizenship, and the development and improvement of those theories. (2) The raising of academic and scientific standards within t he
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Flexible, Fast and Future Production Processes' under Seventh Framework.

assistant: **Concept**

The F3 consortium’s vision is that the EU’s chemical industry’s competitive position would be strongly enhanced if it could operate modular continuous plant (F3 plant) which combines world scale continuous plant efficiency, consistency and scalability with the versatility of batch operation. Our project will deliver such a radically new production mode based on: a)   Plug–and–play modular chemical production technology, capable of widespread implementation throughout the chemical industry. This technology uses generic backbone facilities designed for rapid interfacing with standardized process equipment containers (PEC). The PEC house process equipment assemblies (PEA) composed of intensified process equipment for fast, flexible future chemical production  b)   Holistic process design methodology applying process intensification concepts and innovative decision tools. This will accelerate process development and provides a substantial reduction in energy consumption, raw material usage and plant volumes. Our consortium of leading academic & research institutions and 7 major synthetic chemical producing industrial companies has 3 main goals:  1. To prove the technical feasibility of the F3 mode of manufacturing by building and operating a 0.1 to 30 kg/hr demonstration facility,  2.  To demonstrate that operation of F3 plant will be more economical, ecoefficient and more sustainable than conventional production modes like large scale continuous or small to medium scale batch processing.  3.  To drive a step change in the technology available to EU chemical production and engineering companies by designing intensified equipment for reaction and down stream processing, dissemination of standards for plug and play modular plant and providing open access to the backbone facil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'European Doctorate in the Social History of Europe and the Mediterranean' (2002-2006).

assistant: **Concept**

The European Doctorate in the Social History of Europe and the Mediterranean (ED) provides qualitatively innovative early stage training for doctoral students. It is open to all students enrolled for a doctoral degree in history and related disciplines researching on any period of Europe's history, from its classical origins to the present day. The ED is a consortium of departments of history and related disciplines in ten leading academic institutions in different European countries. Coordinated by the Università Ca'Foscari Venezia (Italy), the network partners are: Università Ca'Foscari Venezia (Italy); National and Kapodistrian University of Athens (Greece); Universität Bielefeld (Germany); Slovak Academy of Sciences, (Slovakia); Rijksuniversiteit Groningen (Netherlands); Instituto de Ciências Sociais da Universidade de Lisboa (Portugal); University College London (United Kingdom); Ecole Normale Supérieure de Paris (France); Universidad Pablo de Olavide de Sevilla (Spain); Södertörns högskola (Sweden).The ED is directed towards doctoral students who can benefit in terms of research for their dissertation from a period of mobility in the doctoral school of one of the consortium universities in another country. Each researcher participates in the regular postgraduate training and research seminars of the host university, where he is guided by an expert supervisor. At the beginning of the year, all researchers who have been awarded a fellowship, together with an academic from each of the ED participant institutions, take part in an introductory seminar; at the end of the academic year, a second seminar is held, in which the ED fellows present the results of their research during their period of mobility and assess its significance in terms of the overall trajectory of t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'A climatic or tectonic control on early primate dispersal? A new approach to investigate species dispersal in deep time' (DISPERSAL).

assistant: **Concept**

Recent studies show that the distribution of many modern terrestrial species can be explained by a handful amount of large-scale dispersals and that these episodes will likely become more numerous under climatic stress. However, the underlying mechanisms governing these dispersals remain nebulous. Long-distance dispersals across marine barriers, often referred to sweepstakes dispersals, have always been assumed to be an unpredictable process in which taxa overcome a geographic barrier in a random manner. Yet, there are many instances of dispersals across marine barriers that appear coordinated and non-random. New paleontological findings show that during a short time period marked by intense climate variations, 40 to 35 million years ago, Asian anthropoid primates and rodents crossed 500 km of Tethys Sea to reach Africa and 800 km of South Atlantic Ocean to reach South America. This proposal aims to build an empirical and theoretical basis for the origins and mechanisms of long-distance dispersals by resolving: how did primates and other mammals disperse across two major seaways? What are the external forcing mechanisms that make transoceanic dispersals non-random? This project proposes a combination of paleoclimatic, paleogeographic, and paleontological approaches to evaluate the mechanisms of species dispersal and diversification in deep time, applied to the early dispersal of anthropoid primates. This research will set the founding steps of a holistic method to evaluate the mechanisms of all dispersal events in deep time, allowing new interpretations about the modern, past and future distribution of species; it will additionally solve one of the biggest mysteries in paleontology, as this episode ranks among the most pivotal events during all of primate evolutionary h
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The Flagship ERA-NET' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

FLAG-ERA, the Flagship ERA-NET, gathers national and regional funding organisation with the goal of supporting, together with the European Commission, the FET Flagship initiatives and more generally the FET Flagship programme. Most funding organisations in Europe participate, either directly or as associated members. FLAG-ERA contributes to the construction of the two Flagship initiatives on Graphene and Human Brain research, through a range of activities such as the launch of joint calls supporting transnational projects in synergy with the Flagships, contribution to the Flagship partnering framework, identification of potential partnering projects, information on funding opportunities for the Flagships, and networking events. The activities in FLAG-ERA are organised around periodic events gathering all stakeholders and structured in sessions dedicated to the various objectives and related tasks of the project. FLAG-ERA II is the second ERA-NET project, implemented as an ERA-NET Cofund, starting in December 2016 for a period of 6 years, following the first FLA-ERA ERA-NET project which lasted from October 2013 to November 2016.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Bringing the field of psychiatry forward: Unraveling heterogeneity of Depression' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Depression is a highly prevalent disorder associated with substantial costs, and predicted to be the leading cause of disability in 2030. Although there has been substantial progress in our understanding of the biological processes and environmental exposures associated with mood disorders, application of newer technologies such as neuroimaging and molecular biology have not resulted in major breakthroughs in our understanding of depression, particularly with respect to treatment. One of the major reasons for this lack in breakthroughs is the substantial heterogeneity of major depression. In-depth characterization of biological correlates of subtypes can inform our understanding of the sources of heterogeneity that may index different etiological pathways. In addition, clinical presentation of depression forms an important component in research on depressive subtypes. Recent evidence suggests that disturbances in activity, sleep, appetite and circadian patterns may be more important than mood changes as core features of depression, but measurement of these domains relies on self-reported, retrospective assessments. Objective ambulatory methodologies, including Actigraphy and ecological momentary assessment (EMA), may be valuable in defining the core features of depression subtypes more accurately. In addition, these technologies are relevant to future research and clinical practice through applications in interventions and continuous patient monitoring.This proposal aims to unravel the heterogeneity of depression by: 1) Systematical characterization of depressive subtypes on a wide range of biological measures to increase insights into the differential etiology of depressive subtypes and bring us one step closer to improved treatments, and 2) Incorporation of accurate,