RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'A novel touchless method and eHealth system for automated urine monitoring' to be submitted under Horizon 2020.

assistant: **Abstract**

Medipee is a young and innovative SME who aims to improve life quality of its customers through automated health care and monitoring.  Classical urine tests are tedious and normally mean a visit to a doctor combined with a waiting period for the results. The Medipee project aims to optimize, industrialize and commercialize a unique automated urine testing device which can be used by patients at their homes and eliminates the need to go to the doctor for this procedure. To reach this goal, our team combines years of experience in the field of product development, engineering science, medical engineering and marketing.  In the period from 2019 to 2023, we expect to grow in terms of internationalization with+80% larger commercial network, to enter new markets. We also envisage a 60% increase in investment in R&D and generation of new IP to extend the product life-cycle. In terms of business volume, we aim at increased revenue (NPV=€5.0 million, ROI=0.26), from sales generated by Medipee and the creation of 9 new permanent job positions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Health.E Lighthouse Support Initiative' under Horizon 2020.

assistant: **Concept**

The objective of the HELoS CSA is to support the Health.E Lighthouse Initiative Advisory Service (LIASE) in its ambition to accelerate innovation in medical devices (“Moore for Medical”).Health.E will accelerate the innovation in medical devices and systems by stimulating the development of open technology platforms and standards , thereby moving away from the inflexible and costly point solutions that presently dominate electronic medical device manufacturing. Open technology platforms, supported by roadmaps, will generate the production volumes needed for sustained technology development, resulting in new and better solutions in the healthcare domain.Health.E will:•Translate the needs of medtech and pharma into ECS opportunities;•Build on the ECS Strategic Research Agenda and identify the gaps;•Stimulate initiatives: towards open technology platforms and standards for medical devices;   to anticipate the requirements for regulatory, Notified Bodies, clinical trials and market access; to better apply to the current care practices, necessary conditions for market access.•Connect to European initiatives and relevant communities including PPPs such as ECSEL, IMI, Eureka, and relevant industry associationsIn the HELoS CSA, three main components are identified that need to be connected in order to address the complex issue of innovation in the medical industry: •Connecting existing networks: ECSEL projects, (inter)national and regional projects and initiatives;•Addressing and connecting scientific/technical issues and non-technical aspects e.g. legal, regulatory, standardization, ethical, economic (cross-cutting issues);•Extending the network of stakeholders and markets across Europe (spreading excellence, facilitating international collaboration, new applications);•The dis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Energy-aware Factory Analytics for Process Industries' in the context of a Horizon 2020 call.

assistant: **Objectives**

It becomes apparent particularly in process industries that cognition can improve the behaviour of a complex process system. One of the main expectations of the use of digital twins is to give us the capability to observe and monitor the behaviour of their respective physical twins. In order to make it happen, we need to combine digital twins, which are driven by domain models (i.e. knowledge), with the models derived from data (i.e. experience). In order to realize it, we need a real-time processing layer where observations (i.e. events), knowledge and experience interoperate to understand and control the behaviour of a complex system (i.e. cognition). FACTLOG offers such a layer and aims at deploying and adjusting it to several process industries.By incorporating different pipelines of machine learning and analytical tools at different levels (from machines to process steps and from processes to the whole production plant), FACTLOG enables the realization of the Cognitive Factory as an ensemble of independent but intertwined ECTs, that are (i) able to self-learn, and thus to effectively detect and react to anomalies and disruptions but also to opportunities that may arise, (ii) enjoy a local or global view of operations and (iii) are capable for short-, mid- and long-term reasoning and optimization.FACTLOG is driven by several specific, yet indicative, business cases in the process industry and focuses its innovation regarding analytics, AI and optimization on the deployment and assessment of coherent Enhanced Cognitive Twins for the specific sectors represented in FACTLOG and even for the plants in which it will be pilot tested and evaluated. It will be implemented by a just right consortium of twenty partners, five of which are manufacturers and a further three repr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Statistical and dynamical analysis of collective behaviour in a three-dimensional motion: Empirical studies and modelling' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Collective behaviour is ubiquitous in living systems such as flocks of birds, swarms of insects or schools of fishes. It occurs for several reasons which go from predator protection to mating. To better understand those living systems it is therefore important to understand how collective behaviour emerges and its features. For large flocks of birds and swarms of insects little work has been made from the perspective of empirical and statistical analysis towards modelling of different types. This proposal aims to make a comprehensive data acquisition of three-dimensional data of position and trajectories of elements in groups of flying animals for posterior statistical, dynamical and non-linear analysis characterisation and consequent modelling. It corresponds to the first broad approach to collective phenomena starting from measuring real features in order to reproduce them. After this study it will be possible to understand to fundamental principles of aggregation of birds and some species of insects and to appraise whether those mechanisms are common in flocking and swarming. To that, a interdisciplinary approach involving the fields of Biology (Animal Behaviour),
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Countering Jihadi Insurgencies in Africa:  Repress, Resist & Reorder' (COUNTERRR).

assistant: **Innovation**

Many African countries, including Libya, Nigeria, Mali, DR Congo, Somalia, and Mozambique, have been affected by violence of jihadist armed groups. These groups pose a distinct threat to social, political, and economic orders across Africa as they violently reject the nation-state and can rely on support from the transnational violent networks of the Islamic State and al-Qaeda. Research has primarily focused on international responses to “violent extremism” in Africa, but international actors do not operate in a vacuum and interact with responses on the ground. If we want to understand and effectively tackle this violent threat, we need to know more about how domestic actors—governments, security forces, and affected communities—counter jihadist armed groups in Africa. Why do some governments repress these groups through domestic security operations, while others invite foreign countries to militarily intervene? Why do some governments respond immediately, while others delay a response to a new jihadist threat? Why do some communities decide to cooperate with jihadist groups, while others opt to resist them? Why do some communities attempt to resist these groups non-violently, while others form self-defence militias to protect themselves? And finally, how do domestic responses to jihadist armed groups reorder security in the region and shape conflict stabilization or escalation? COUNTERRR will deliver crucial analyses of when, how, and why domestic actors repress and resist jihadist armed groups and reorder security. It will adopt an innovative multi-level and multi-method comparative approach focused on variation within and across three countries (Mali, Nigeria, and Mozambique). Understanding how African countries and affected communities respond to jihadist insurgenci
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'New Sustainable Fiber Production Technology' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Textiles industry is one of the largest consumers industries globally, generating €1.5 trillion annually. The overall consumption of apparel is on the rise, promising further growth to the industry. However, textiles industry is also one of the most polluting industries producing 1.2 billion tonnes of CO2 equivalent per year. Thus, the industry is under immense legislative pressure. In addition, there is a shortage of supply of raw materials.Natural fibers like cotton require massive amounts of water, whereas viscose production utilises hazardous chemicals. Oil-based alternatives, like polyester, are the largest contributors of plastic microfibers in oceans.These trends are forcing the textiles industry to actively look for alternative raw materials. If they cannot find one, their profits will drop significantly in the next decades.Finnish SME Infinited Fiber Company (IFC) has developed low-cost process for producing cellulose based fiber from textiles waste. The fiber product – called Infinited Fiber – is sustainable, affordable, and available in unlimited quantities. Unlike viscose and polyester, Infinited Fiber has the touch and feel of cotton, which is preferred by consumers. It is the only fiber that meets the industry needs.IFC has already built an industrial pilot for producing 50 tons of Infinited Fiber annually. The whole capacity of the pilot has been acquired by some of the biggest fashion brands in the world. More than 15 brands have tested the fiber product with extremely positive feedback. They are now looking forward to launching Infinited Fiber based consumer products.The NewNormal project will support the scale-up of Infinited Fiber production. As a result of the project, we will reach the commercialisation phase of Infinited Fiber.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Quantum chaos in low dimensional systems - 2 and higher dimensional cat maps'.

assistant: **Concept**

This proposal concerns the quantization of cat maps, a family of completely chaotic dynamical systems. The most important applications are to atomic and molecular physics/chemistry and to disordered mesoscopic systems. This topic is related to current European Community research programmes concerning nonlinear phenomena and complex systems. The aim of the project is to develop the investigations of these systems in two directions. The first one is to try to prove an analogue of the Sarnak conjecture for cat maps. This essentially means to verify that the maximum value taken by quantum eigenfunctions is O(h -E) as h to 0 for any positive E. The second direction will be to quantize linear maps on 2n-dimensional tori with n > I and to study the semiclassical properties of their Anosov perturbations. The study of higher-order systems is only now being contemplated, and the cat maps and their perturbations provide the simplest models to work with.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Identification and targeting of metabolic pathways in dendritic cells that regulate their immune polarizing function' in the context of a Seventh Framework call.

assistant: **Objectives**

Dendritic cells (DCs) are key regulators of both immunity and tolerance by controlling activation and polarization of effector T helper cells (Th) and regulatory T cell responses (Treg). Therefore, there is a major focus on developing approaches to manipulate DC function for immunotherapy. It is well known that changes in cellular activation are coupled to changes in cellular metabolism. However, only recently, based on studies with T cells and macrophages, the picture is emerging that manipulation of cellular metabolism can be used to shape immune responses. This field of immunometabolism is rapidly evolving as one of the new frontiers in science. Nonetheless, little is known about the metabolic processes that support DC activation or about the metabolic requirements for DCs to drive Th1, Th2 or Treg responses. My proposal aims to fill this gap and focuses on the novel concept that cellular metabolism regulates the immune-polarizing properties of DCs.Based on my recently published work and preliminary data, I hypothesize (1) that DCs priming Th1 responses are metabolically characterized by a switch to glycolytic metabolism, whereas Th2- or Treg-polarizing DCs, have a catabolic kind of metabolism that is dependent on mitochondrial fatty acid oxidation and oxidative phosphorylation and (2) that these states of metabolism are required for their immune-polarizing capacity.To address this, my project aims (a) to characterize and compare the metabolic profiles of Th1-, Th2- and Treg-polarizing DCs and (b) to determine whether their metabolic programs underpin their T cell-polarizing capacity. (c) Based on these findings I aim to determine whether deliberate modulation of glycolytic or mitochondrial metabolism can alter the immune-polarizing capacity of DCs in such a way that
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Intuitive decision making and bias: Examination of their role in the initial mental-health intake with ethnically and racially diverse populations'.

assistant: **Concept**

The proposed project investigates the complexity of provider decision-making process during the initial mental-health interview (intake) with ethnically and racially diverse populations. We focus on examining intuitive decisions and explore the effect of explicit and implicit bias on decisions related to patient care, including, diagnosis, treatment recommendations, and assessment of rapport. Making medical decision during the mental health intake is the foundation for the proper patient care, but can be a challenging goal given the high level of uncertainty it involves. Such uncertainty is more pronounced in making intuitive decisions with diverse populations. However, little is know about the mechanisms contributing to clinical uncertainty and particularly to intuitive decisions.The current proposal aims to bridge this gap and reduce mental health service disparities by improving intuitive clinical decisions and reducing bias with ethnically and racially diverse populations. It builds on the Institute of Medicine’s (2002) analysis highlighting the role of biases, stereotyping and uncertainty in the patient provider interaction as contributors to service disparities. The specific aims of the study are: Aim 1: investigate the effect of explicit and implicit bias on intuitive decision making through a quantitative experimental design with a on-clinical sample. Aim 2: investigate the effect of explicit and implicit bias on intuitive decision making through a mixed methods experimental design with mental health clinicians providing services to ethnically and racially diverse population. Aim 3: assess clinician reactions to the recommended improvements to the decisions making process developed in Aims 1 and 2, using consensus groups. At the end of this project we hope to ma
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Impact of climate change on carbon flux in freshwater ecosystems'.

assistant: **Concept**

The overall aim is to understand the impact of rising CO2 and temperature on the structure and dynamics of lake ecosystems. This project will be the first undertaken where a rigorous understanding of the response of freshwater ecosystems to climate change is addressed in a holistic way, including response patterns at different functional levels integrated up to a manipulated ecosystem study. A model will be produced to improve generality and prediction capability of the effects of climatic change and for use as a tool for water managers Freshwaters are very comlex systems, whose functioning is controlled by feedback processes between physics, chemistry and biology. In order to assess the impact of climate change on freshwaters it is therefore necessary to understand the mechanisms of response at a physiological level and scale this up through community structure to an ecosystem level. In order to achieve this we have chosen a hierarchical approach culminating in ecosystem manipulation experiments to test the predictions gained at lover levels of study. - Laboratory studies to determine the response of individual organisms or functional groups to changes in environmental variables. The responses measured will include photosynthesis, growth rate, metabolic rate, chemical composition and extent of acclimation. - Field studies to assess the sensitivity of the different groups of primary producers, phytoplankton, submerged and emergent macrophytes, to increases in CO2 concentrations in lakes from a range of trophic types and varying in thei water hardness and hence background concentrations of inorganic carbon. - Ecosystem manipulations to assess interactions between subprocesses and their effect on community structure and organic carbon flow and whole-system response to inc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Analysis of nmda receptor function in chimaeric mice' (1994-1998).

assistant: **Innovation**

The NMDA subtype of glutamate receptors plays a critical role in neuronal development and function, and has been identified as an essential component in LTP, an intensely studied cellular correlate of learning and memory. The gene for the major subunit NR1 was deleted in mice through homologous recombination techniques, but mutant mice die on the day of birth. The current project aims at rescuing the phenotype of cells lacking NMDA receptor function by a chimaera approach: ES cells containing the double NR1 knockout are used to generate chimaeric mice. Double knockout cells in the brain can be identified by virtue of a marker gene (lacZ. These cells can be analysed by morphological criteria, antigen expression patterns, in situ hybridisation techniques, and whole cell and single channel recordings to better understand the consequences of lacking NMDA function in important parts of the brain, like hippocampus, striatum, cortex and cerebellum.