RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'FOSTERING TALENT ECOSYSTEMS FOR EARLY-STAGE RESEARCHERS IN DEEP TECH' (DeepTechSeeds) targeting Horizon Europe.

assistant: **Abstract**

DeepTechSeeds addresses the critical need for a highly skilled and adaptable research workforce in Europe's deep tech sectors. As global competition intensifies in fields such as artificial intelligence, quantum computing, robotics, and advanced materials, the project aims to create a dynamic and interconnected talent ecosystem that seamlessly bridges academia, industry, and the public sector.The project's core objective is to reshape the landscape of early research careers in deep tech fields by implementing a comprehensive framework based on the new Charter for Researchers. This framework will guide participating organizations through a process of structural change, creating more attractive and sustainable career pathways for Early Career Researchers (ECRs).DeepTechSeeds will:1.Develop and implement a tailored DeepTech Framework for applying the Charter for Researchers in deep tech sectors.2.Enhance ECR competencies through targeted training modules and open innovation programs, training at least 500 researchers.3.Facilitate balanced talent circulation across sectors and regions, establishing at least 10 new cross-sector collaborations.4.Create a digital DeepTech Talent Ecosystem Platform to facilitate networking, knowledge exchange, and career opportunities.5.Organize open innovation challenges to foster collaboration between ECRs and industry partners.6.Provide evidence-based policy recommendations for scaling the talent ecosystem model across the European Research Area.DeepTechSeeds serves as a comprehensive effort to create a self-sustaining ecosystem that nurtures talent, drives innovation, and strengthens Europe's position in critical deep tech fields. By addressing the challenges faced by ECRs holistically – from working conditions and skills development to cro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Unlocking the potential of cryo-electron tomography by simplification of the sample preparation workflow' (Cryo-SECOM) under Horizon 2020.

assistant: **Objectives**

Cryo-electron tomography (cryo-ET) is a powerful technique that can faithfully image the native cellular environment at nanometer resolution and enables the acquisition of 3D images of large and pleomorphic objects, such as cells and organelles, with unprecedented resolution. The main problem in the current cryo tomography workflow is the multiple critical steps needed to make the sample suitable for analysis. Current labs use a workflow that involves at least 22 steps, limiting the throughput to the creation of only one sample a day, and with a low yield of the analysis due to contamination of the sample during the transfer steps.Delmic has completely reimagined the cryo-ET workflow, with the ultimate vision of completely automating sample preparation. Central to this workflow is the cryo-SECOM, which integrates a correlated cryo light microscope with a FIB/SEM system. Additionally, a unified carrier simplifies the placing and carrying samples around and the sample handling and loading/unloading procedures are automatized. We will tie all workstations together, basically creating a ‘cryo-ET sample prep robot’. This fully integrated workflow approach reduces the switching between many workstations, gives higher yield, and offers unprecedented precision in targeting the area of interest. By simplifying the workflow and reducing the preparation time, cryo-SECOM will allow researchers to innovate faster, decreasing the sample preparation time by 87% and improving the yield by 8-fold. The cost per sample will be greatly reduced by 90%. Cryo-SECOM will be key in unlocking the full potential cryo-ET, opening new horizons in structural biology research that will have broad application to address fundamental questions in microbiology.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project '2nd International Symposium on Obesity and Hypertension Genetics and Molecular Mechanisms 25. - 27. October 2001, Berlin' (1998-2002) under Fifth Framework.

assistant: **Objectives**

Overweight and obesity currently affect 40-60 % of the adult population in the EU. Obesity is a prime risk factor for the development of hypertension and other cardiovascular abnormalities and, therefore, directly contributes to a large proportion of cardiovascular morbidity and mortality. However, the mechanisms underlying the relationship between increased body mass and hypertension remain poorly understood. Recent years have seen a remarkable advance in our understanding of the molecular biology of adipose tissue. Adipocytes are now recognised as an important source of a variety of molecules that have a direct impact on cardiovascular and renal function. Understanding these factors can be expected to lead to new preventive and therapeutic strategies towards managing obesity and its cardiovascular sequelae.Currently, interaction between the scientific community involved in the fields of cardiovascular medicine and obesity are rudimentary at best. Consequently, the vast majority of cardiovascular researchers know little about the biology or pathophysiological significance of adipose tissue. Furthermore, few European centres are actively involved in obesity research. Academic courses on obesity are virtually non-existent at most academic institutions across the EU.The aim of ISOH '01 is to bring together a distinguished faculty of leading researchers and opinion leaders from the fields of obesity and cardiovascular research to discuss and exchange ideas and findings relevant to both fields. This high-level meeting should also provide a state-of-the-art overview of recent developments in the two fields, both as training experience and a stimulus for further research in the areas uniting these disciplines.The need for such a meeting is also reflected by the official endor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Indium-Phosphide Pilot Line for up-scaled, low-barrier, self-sustained, PIC ecosystem' (InPulse), addressing dissemination and exploitation.

assistant: **Impact**

InP photonic integrated circuits (PICs) offer game changing performance capabilities across multiple market sectors. Alas, the possibilities have so far been restricted to a small number of vertically-integrated technology businesses. Europe boasts tens of innovative businesses who are positioned to develop PIC-enabled technologies , but – alas again – they do not have access to mature,  fast-turnaround predictable, high performance production. InPulse is a manufacturing pilot line for InP PICs which will transform the PIC industry from a vertically integrated model with all skills in-house within a small number of specialized businesses, to an open-access horizontal model accessible to all European innovators. InPulse puts in place the technological and operational processes to: 1)Accelerate the uptake of PIC technology in new markets: enabling SMEs to create tens of products in markets where PICs have not be used before.2)Enable sustainable production in Europe creating aligned, scalable and inter-locking services and value chains3)Accelerate time to market from years to under 24 months with predictive design for fewer and faster product design cycles4)Qualify foundry processes, to TRL7, sharing process optimization across productsInPulse combines low entrance-threshold, mature-manufacturing to enable tens of European PIC innovators. InPulse is validated by:•A “Pilot Line Validation Program” with two Participants stretching performance •A “Demonstrator Open Call” program enabling external users to take thirty designs to pre-production •High frequency open access calls, sustainable beyond the end of the project InPulse partners have played a pioneering role in open access InP PICs, creating an infrastructure for research and early stage development. We are very well po
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'EUROPEAN EVENT ON INDUSTRIAL TECHNOLOGIES - INDTECH 2022' (2021-2027) under Horizon Europe.

assistant: **Objectives**

The European Industry is currently facing growing number of challenges and the status quo is not acceptable as a sustainable solution. The two main trends of Green and Digital transformation is a strategic call for action for all individual companies, but more and more also between them. The trends of shortening of value chains not only from technological and data-use point of view, but also from de-internationalization perspective became very urgent as recovery measures after the Covid-19 pandemics and will be considered as a potential driver for future resilience building strategies. At the same time, the existing workforce will need to accept and adopt the proposed changes as a new opportunity for sustainable growth, which shall be supported by development of new skills and largely available re-skilling. These and other aspects will be promoted and opinions from industrial leaders collected at the next pan-European conference on Industrial Technologies in Grenoble 2022, France. The feedback will be provided for further policy work on European, national and regional level.


**Keywords:** Industrial technologies, event, green transition, resilience
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Characterization and quantitative modeling of DNA mismatch repair and its role in the maintenance of genomic stability and cancer avoidance' (MISMATCH2MODEL) under Seventh Framework.

assistant: **Objectives**

Mismatch2model: Characterization and quantitative modeling of DNA mismatch repair and its role in the maintenance of genomic stability and cancer avoidance  DNA mismatch repair (MMR) plays a crucial role in the maintenance of genomic stability. In both bacteria and eukaryotes, the loss of mismatch repair gives rise to a mutator phenotype. In hereditary non-polyposis colon cancer (HNPCC) families, germline mutations in one MSH2, MSH6 or MLH1 allele predispose to cancer of the colon, endometrium, ovary and other organs. HNPCC is the most frequent form of familiar cancer.  In the mismatch2model project we adopt and exploit a systems biology approach in which we combine Europe’s expertise in DNA mismatch repair with sophisticated multidisciplinary technology and expertise in quantitative modeling in order to describe this DNA repair process at different levels of complexity. The multidisciplinary consortium will have the following tasks that relate directly to the topics raised in Call HEALTH 2.1.2.5: - Gather quantitative and structural data sets describing the principal steps of DNA mismatch repair - Integrate and analyze structural and functional data obtained from single molecule and bulk studies - Develop mathematical models for single and/or multiple steps of the MMR pathway - Perform analyses at different levels of complexity: from recognition of the mismatch through repairosome assembly to in vivo function - Combine the well-understood MMR E.coli model system with the cancer-protective human system The combination of the individual strengths of the multidisciplinary groups involved in this program ensures that significant progress will be made towards the understanding of this complex process.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Approximations to dynamic density functional theory - phase field simulations on atomic scales' (PHASEFIELD).

assistant: **Innovation**

A recent innovation in materials modeling has been the phase field crystal model. Instead of a phenomenological phase field variable the quantity of interest is the atomic number density. This formulation has made it possible to incorporate the kinetics of phase transformations with properties of solids that arise due to their periodic structure. This includes elastic strain, topological defects, vacancy diffusion and polycrystalline grain boundary interactions. The appealing feature of the phase field crystal model is its connection with classical density functional theory, which allows material specific simulations on diffusive time scales, orders of magnitude larger than classical molecular dynamics.Our mission is to foster international cooperation in phase field crystal modeling and serve as a platform for addressing global challenges in materials science by using the phase field crystal approach. Applications of interest are self-assembly of quantum dots in thin film growth and fluid-structure interactions in microfluidics.We involve participants from diverse sectors, regions and science and engineering disciplines which have already proven to be able to work together efficiently.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Toward Precision Toxicology: New Approach Methodologies for Chemical Safety' (PrecisionTox).

assistant: **Innovation**

The goal of PrecisionTox is to advance safety assessment of chemicals without the use of animal testing by establishing a new, 3Rs-compliant, cost-effective testing paradigm for chemical safety assessment — Precision Toxicology — that identifies molecular key event (KE) biomarkers predictive of chemically induced adverse health effects in humans and facilitates their uptake into regulatory and industry practice. This goal is supported by three core concepts: PhyloToxicology, which replaces mammal models with an evolutionarily diverse suite of non-sentient animal species from across the tree of life; Quantitative Susceptibility, which determines safety factors based on genetic variability; and Embedded Translation, which engages key stakeholders in project planning, selection of chemicals for investigation, and case studies for regulatory application. We accomplish this goal through six objectives: ● Stakeholder Integration, embedding the Stakeholder Advisory Group in project management (WP1); ● Comparative Toxicology, utilising high-throughput testing methods across five non-sentient species and human cell lines to observe toxic response (WP2); ● Molecular Data Production, applying metabolomics and transcriptomics to comparative toxicology samples to trace adverse outcomes via the molecular key events preceding them (WP3); ● Quantitative Susceptibility, applying quantitative genetics and gene expression profiling to understand variation in individual susceptibility and develop empirical exposure thresholds (WP4); ● Biomarker Discovery, PrecisionTox Data Commons, and NAM Toolbox, using machine learning to identify biomarkers for molecular key events and creating the dissemination and translation products for their use (WP5); and ● Regulatory Analysis and Application, par
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Parameterization of the aerosol indirect climatic effect', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

Problems to be solvedReliable predictions of climatic change are impossible unless the magnitude and distribution of the anthropogenic perturbations of the climate can be quantified. The radiative effects of greenhouse gases are well understood; but the indirect effects of anthropogenic aerosols, that operate by altering cloud properties, are potentially significant and are very uncertain. Scientific objectives and approach The project aims to address these problems directly, using the unrivalled data sets of co-located observations of aerosols, in cloud properties and radiative fluxes obtained during the ACE-2 field campaign. The measurements will be compared with cloud properties and radiative fluxes simulated by several climate models, with the objective of rigorously assessing the models and developing and testing more realistic schemes for representing aerosol-cloud-radiation interactions in climate models. The results of the ACE-2 Cloudy-column experiment will be examined and extended to the scales that are significant for GCM parameterisations, namely 100 km in space and 1/2 hour in time. The quality of the closure, that has been evaluated at the scale of the physical processes, will be evaluated at the GCM scale. The assessment will be focused on the four processes which are identified as the most important for the aerosol indirect effect (AIE), namely aerosol activation, microphysics/radiation interaction, drizzle formation and feedback, and cloud dynamics and homogeneity. The variables used for describing the physical processes will be examined in term of large-scale statistics and the corresponding large-scale variables will be defined. Special attention will be given to non-linear processes, which cannot be parameterised with the mean value and the standard
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Revealing the neurocognitive mechanisms underlying the visual perception of social interactions' (POINTS) targeting Horizon 2020.

assistant: **Abstract**

“Social perception” has emerged as an umbrella term to describe research addressing the visual perception of others. To date, this discipline has focused on the perception of individuals; for example, researchers have examined the visual processing of faces and facial expressions, body shapes and postures, actions and kinematics. The resulting body of research suggests that social stimuli are detected by specialised mechanisms, recruit dedicated perceptual models, and are processed by particular neural substrates. However, while social perception research has made considerable progress elucidating the visual perception of individuals, virtually nothing is known about the visual perception of social interactions; how we detect, encode, and interpret visual displays of social interactions viewed from third-person perspectives. Given the adaptive value of accurate interaction interpretation, this paucity of knowledge represents a remarkable gap in our understanding of social perception. POINTS will develop a battery of original behavioural and neuroimaging paradigms to reveal the neurocognitive mechanisms that mediate this essential form of social perception. The overarching objective of POINTS will be achieved by addressing five research questions: 1) Do observers exhibit evidence of interaction detection mechanisms? 2) How do we process fleeting visual displays of social interactions? 3) How do we represent dynamic interaction change? 4) Do specialised neural substrates mediate interaction perception? 5) Do some observers exhibit impaired interaction perception? The POINTS project represents a significant step-change in social perception research. Understanding the mechanisms of interaction perception will provide new insights into the organisation of the human visual sy