RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Advancing Phage Therapy through Synergistic Strategies: Phage-Mediated Killing and Competitive Exclusion using Engineered Prophages', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Amid the antibiotic resistance crisis, the century-old practice of phage therapy, the use of bacterial viruses to treat bacterial infections, has gained renewed attention. Despite extensive research and clear-cut advantages over antibiotics, phage therapy has yet to gain momentum. This is primarily due to remaining limitations, e.g., the time-consuming process of identifying suitable phages and limited in vivo efficacy. With PHAGE-PRO I propose a new technology to overcome the shortcomings of traditional phage therapy. Unlike the conventional use of lytic phages, I will capitalize on prophages – viruses that integrate into bacterial genomes capable of excision and replication. By integrating prophages into safe carrier strains, originating from probiotics, I will unlock two pivotal benefits, (1) rapid identification of suitable phages using advanced machine learning, (2) sustained in-vivo efficacy. Yet, the core advantage of PHAGE-PRO lies in its unparalleled synergy of phage killing and pathogen competitive exclusion imposed by the probiotic.To realize this concept, the development of predictive tools is essential to quickly identify the most promising prophages and probiotic combinations for each pathogen (WP1). Prophage engineering (WP2), followed by rigorous in vitro testing will ensure a high safety and efficacy. High-throughput in vivo experiments using wax moth larvae will reveal the most promising candidate which I will subsequently validate through a proof of principle experiment using a poultry model (WP3).Although I initially tailored PHAGE-PRO to treat Salmonella infections in poultry, its impact extends far beyond: This new technology holds the potential for transformative changes in phage therapy, not only advancing infection management in livestock farmin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Anisotropic deformation of nickel based superalloys modelling and validation'.

assistant: **Innovation**

Research objectives and content The project is to expand and finish the assessment of an existing modelling program of the mechanical anisotropic behaviour of nickel based single crystal superalloys under creep. Expansion of the use of the model concerns the type of simulated tests (work already started) and targets the simulation of constant strain rate tests. That point needs now complementary validations and will be extended taking temperature as another parameter. The expansion of the model will laso include adaptation to another alloy. Two versions of the current program exist: one for UNIX systems in C language, one in PASCAL for PC. A choice will be made in which one is the best to be adapted for further work. Training content (objective, benefit and expected impact) The final aim is to create a basis for engineering design that can be included in a finite element approach in the future. This post doctoral period will help me to deepen my knowledge in superalloys, will make me acquainted with modelling the mechanical behaviour of materials. I will learn the Electron Back Scaterring Diffraction technique and will reinforce my knowledge on UNIX, and on C and PASCAL language. Links with industry / industrial relevance (22) DRA and EGT are the industrial partners, they are largely involved in this proposal. Regular contacts will occur with both. Some experimental tests will be regularly performed by DRA.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Safely Optimized Runway Throughput' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The expected rapid growth in air traffic will lead to an increasing number of capacity constrained airports. Therefore airports have to improve significantly the runway and airport throughput while maintaining or increasing runway safety levels. In SESAR 2020 WAVE-1 this was mainly addressed by PJ02 with the four solutions:      PJ.02-01: Wake turbulence separation optimisation    PJ.02-02: Enhanced arrival procedures   PJ.02-03: Minimum Pair Separations based on required surveillance performance      PJ.02-08: Traffic optimisation on single and multiple runway airportsThis VLD covers four solutions:The use of aircraft type-specific pairwise separation will be used at Heathrow Airport, focusing on the runway occupancy time part of the overall TBS concept. At Vienna, the use of a wake decay enhancing device is intended to be demonstrated. There will be a demonstration at Zurich Airport of a concept known as ROCAT, which enables a reduction in the surveillance separation minimum for in-trail pairs on final approach, including a revised runway occupancy time aircraft classification. The benefits of an integrated AMAN-DMAN runway sequencer will be demonstrated at Stockholm Arlanda in shadow mode. Together these demonstrations will collect evidence of the concept(s) within the overall time-based separation concept. As such the proposed large scale demo VLD3-W2 SORT closes the gap between the actual concept development and the deployment (or pre-industrialization) phases by demonstrating the operational and technical readiness. And by doing so de-risking the later deployment phases of  these four solutions, either in real life trials and/or shadow modes trials at major European airports, this will ensure trust in the SESAR results.


**Keywords:** Pair-Wise Separation,Weather
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'In vivo Imaging Genesis and Circuit Integration of Interneurons Engineered from Glia' (IMAGINE).

assistant: **Concept**

Direct lineage reprogramming of cell identity in the nervous system offers the prospect of remodelling diseased brain circuits. Recent years have provided evidence for the possibility of converting brain glia into neurons in vivo. Yet, the process by which glial cells give up their original identity and adopt a neuronal fate remains by large enigmatic. Moreover, it is unclear how neurons induced from glia may integrate into the pre-existing circuits of non-neurogenic brain regions such as the cerebral cortex. Finally, can they participate in cortical information processing and even restore dysfunctional cortical circuits? We have discovered a specific cocktail of reprogramming factors that gives rise to induced neurons with hallmark features of fast-spiking, parvalbumin-expressing interneurons, a neuronal subtype that is highly vulnerable in neuropsychiatric and neurological disorders.  Here, we aim at visualising the conversion of glia into these induced interneurons in real time by in vivo imaging. This will not only unambiguously demonstrate the genuineness of the identity switch, but also unveil cellular intermediates along the reprogramming process. By measuring single cell gene expression during conversion, we will be able to relate intermediate states to their molecular underpinnings. Moreover, in vivo imaging will allow us to follow structural remodelling of dendrites as induced interneurons integrate into pre-existing cortical circuitry. By using in vivo calcium imaging in primary visual cortex, we will examine whether induced interneurons become recruited into sensory information processing circuits. Finally, we will scrutinise induced interneurons for their ability to rescue excitation-to-inhibition balance in a mouse model of endogenous interneuron dysfuncti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The role of water vapor in midlatitude storm track dynamics' under Seventh Framework.

assistant: **Concept**

Atmospheric circulation in the midlatitudes is dominated by regions of strong eddy activity known as storm tracks. These storm tracks transport the bulk of the heat, momentum and moisture in the extratropics. Despite their importance to midlatitude climate much of the mechanisms governing the storm tracks remain poorly understood. Particularly the role of water vapor and latent heat release has received little attention, though the energy release due to latent heating over storm track formation regions is comparable to that of baroclinic processes. This work will investigate the mechanisms controlling the energy budget of storm tracks focusing on the role of water vapor. A hierarchy of models ranging from idealized dry and moist general circulation models (GCMs) to full comprehensive atmospheric GCMs will be used through systematic studies in order to isolate the mechanisms governing the dynamics.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Sea level fluctuations in the Mediterranean: Interactions with climate processes and vertical crustal movements' in the context of a Fourth Framework call.

assistant: **Objectives**

The SELF II project is a follow on project to SELF. The overall aim of the SELF II project is to determine the absolute sea level and its variations and to use them in a comprehensive way to study the present interactions as well as those of the recent past among the ocean, the atmosphere and the Earth's crust and to develop appropriate models to predict future aspects. To improve the long-term monitoring of sea-level variability by applying the most advanced geodetic techniques,  including satellite altimetry and airborne laser; to provide additional sea-level related constraints for the  validation of climate models; to study past sea levels in the Mediterranean in order to further our understanding  of the current processes; to assess the potential hazards in coastal areas in the Mediterranean and to provide  a basis for developing strategies to mitigate these hazards.  To reach the stated objectives a complex of different techniques will be adopted which includes the Global  Positioning System, Water Vapor Radiometry, Absolute Gravimetry, Satellite Altimetry, Airborne Laser  Altimetry and Geological Observations of markers of former sea levels.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Asymptotic properties of moment polytopes of tensors' in the context of a Horizon Europe call.

assistant: **Objectives**

In AsympTensorPolytope I will study the behavior of moment polytopes of families of tensors, as well as their ability to prove bounds on (asymptotic) tensor rank and subrank. I aim to determine properties of the moment polytopes of the unit tensors of varying ranks, as well as matrix multiplication tensors, in particular whether they are distinct from the generic polytopes of their respective format.To achieve this, I will use a combination of the various different descriptions of moment polytopes, which come in representation-theoretic, symplectic-geometric, intersection-theoretic, or more combinatorial forms. In particular, I will study the behavior of moment polytopes under taking direct sums and Kronecker products of tensors, as well as recently obtained computational results.The project has the potential of proving new bounds on the complexity of various tensors, as well as furthering our understanding of Strassen's asymptotic spectrum of tensors. The techniques here can also be extended to understand other settings, such as symmetric or antisymmetric tensors (bosonic or fermionic systems), algebras and quiver representations. As a result, AsympTensorPolytope will have an impact in other contexts such as the complexity of matrix multiplication, quantum information theory and combinatorics.


**Keywords:** Tensor Rank, Moment Polytopes, Representation Theory
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Unraveling the biosynthesis of fatty acid-based lipid polymers in plants', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Cutin and suberin are plant-specific extracellular lipid polymers that are involved in critical water and pathogen barrier functions at the interface between plants and their environment. The biosynthesis of these glycerol- and fatty acid-based polymers remains largely unknown. Understanding how plant cells oxidize, activate, transfer and polymerize acyl chains in the pathway of biosynthesis of cutin and suberin would be helpful to manipulate the composition of plant hydrophobic barriers and obtain crops with higher resistance to pathogens or desiccation. In addition, the reactions of lipid polyester biosynthesis involving oxidized fatty acids are likely to be highly relevant to the bottlenecks that are currently limiting the production in plants of high amounts of omega-hydroxy fatty acids and dicarboxylic acids, which are biomolecules with potential to replace petroleum for the synthesis of polymers and specialty chemicals. The applicant and his colleagues at Michigan State University have identified the first mutant affected in suberin synthesis, characterized a family of glycerol acyltransferases involved in polyester biosynthesis in the model plant Arabidopsis thaliana and shown that these acyltransferases are key partners of P450 fatty acid oxidases for the production of oxidized fatty acids in plant cuticles. In order to further understand the acyl activation, acyl oxidation and acyltransfer reactions required for the biosynthesis of lipid polymers in plants and to identify more players in this pathway, the applicant proposes to: 1) Pursue a knock-out/overexpression approach in Arabidopsis on a larger scale. 2) Co-overexpress various combinations of these Arabidopsis enzymes in yeast in an attempt to characterize their activity and determine the minimal number of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Semidefinite Programming with Applications in Statistical Learning'.

assistant: **Objectives**

Interior point algorithms and a dramatic growth in computing power have revolutionized optimization inthe last two decades. Highly nonlinear problems which were previously thought intractable are nowroutinely solved at reasonable scales. Semidefinite programs (i.e. linear programs on the cone of positivesemidefinite matrices) are a perfect example of this trend: reasonably large, highly nonlinear but convexeigenvalue optimization problems are now solved efficiently by reliable numerical packages. This in turnmeans that a wide array of new applications for semidefinite programming have been discovered,mimicking the early development of linear programming. To cite only a few examples, semidefiniteprograms have been used to solve collaborative filtering problems (e.g. make personalized movierecommendations), approximate the solution of combinatorial programs, optimize the mixing rate ofMarkov chains over networks, infer dependence patterns from multivariate time series or produce optimalkernels in classification problems.These new applications also come with radically different algorithmic requirements. While interior pointmethods solve relatively small problems with a high precision, most recent applications of semidefiniteprogramming in statistical learning for example form very large-scale problems with comparatively lowprecision targets, programs for which current algorithms cannot form even a single iteration. Thisproposal seeks to break this limit on problem size by deriving reliable first-order algorithms for solvinglarge-scale semidefinite programs with a significantly lower cost per iteration, using for examplesubsampling techniques to considerably reduce the cost of forming gradients.Beyond these algorithmic challenges, the proposed research will focus heavily on
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Spectroscopy of Altermagnetic Magnons' in the context of a Horizon Europe call.

assistant: **Objectives**

The magnetic properties of solids form the basis of many modern technologies, ranging from permanent magnets in motors to data storage. Among emerging applications, spintronics is a promising approach to classical computing at THz frequencies, offering miniaturization and improved energy efficiency. Altermagnets, a recently discovered third type of magnetic ordering, are a particularly promising platform for spintronics because altermagnetic magnons combine the key advantages of ferromagnetic and antiferromagnetic magnons. However, due to their only very recent experimental observation, our knowledge of altermagnetic magnons — and altermagnets more broadly — is limited. For instance, theoretically predicted magnon splitting has only been confirmed via inelastic neutron scattering (INS) in one material to date.To address this knowledge gap, I propose ALMAG – a systematic study of magnons in altermagnetic candidate systems using INS and resonant inelastic X-ray scattering (RIXS). These complementary techniques allow for the observation of magnon splitting via INS and the investigation of magnon chirality via polarization analysis on small samples or single magnetic domains using RIXS. ALMAG will leverage the new multiplexing neutron spectrometer BIFROST at the European Spallation Source (ESS), designed for small samples and complex environments, offering superior resolution and flux. As part of BIFROST’s early science program starting in fall 2026, ALMAG will contribute to its optimization and effective use.In the second phase, ALMAG will further expand our knowledge of altermagnets by exploring the tunability of altermagnetic magnons through the combination of high magnetic fields, hydrostatic and uniaxial pressure with INS and RIXS. Overall, ALMAG will confirm or rule o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Interoperability of Interactive and Hybrid TV systems - A new advanced scheme for future services and applications in a global environment' (2007-2013).

assistant: **Innovation**

Parallel to the switchover from analog to digital Television, various interactive digital television systems have developed in various places of the world - some only recently, some already more than a decade ago. The driving idea was to offer consumers additional novative features and multimedia services. As a result of the broadcast-broadband convergence, most TV sets sold today are so-called Smart TVs or Connected TVs that support the current trend of integration of the Internet into modern television sets and set-top boxes.\nHowever, every iDTV and Smart TV system has grown on its own technologies, needs and country laws. Applications written for one system are generally not compatible with another system.\nThe World Broadcasting Union has expressed formally (Declaration on Hybrid and Internet Television, November 2011), the advantages of a common platform, although the Union recognizes that the current situation makes very difficult the creation of such a platform by the normal market rules.\nThe scope of GLOBAL ITV project is now to develop an interoperability scheme that allows several iDTV and Smart TV systems to work together, exchanging and using the information (be it general or personal). The ultimate aim is to lay the foundation for a global interoperable platform.\nMajor Brazilian and European companies, organisations and research establishments have decided to join forces. The consortium is convinced to have at its disposal all means to define and showcase a reliable migration path and a coexistence scenario towards a next-generation hybrid TV platform based on established standards. The extensive experience of all partners, and the advice of the international GLOBAL ITV Council, will ensure the definition of viable solutions with direct traction on the m