RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Laser Induced Synthesis of Biocompatible Multifunctional Inorganic Nanoparticles: A Novel Route to Produce Multifunctional Contrast Agents for Early Diagnosis of Breast Cancer' (NIMBLIS) under Horizon 2020.

assistant: **Objectives**

The main goal of this IF research proposal is to produce novel nanoparticle-based multimodal contrast agents for their use in breast cancer diagnosis by combining Magnetic Resonance Imaging, Digital Mammography, X-ray Computed Tomography and Ultrasonography. In doing so, we will develop a new high-productivity strategy to synthesize multimodal hybrid nanoparticles, which consists in femtosecond-laser-induced-ablation of a metal plate immersed into a solvent containing chemicals, in combination with direct nanosecond-laser photolysis in solution of these chemicals. This research will be coupled to an in situ study of the high-productivity laser fabrication process and the analysis of the underlying mechanisms which allows the nucleation and growth of these hybrid nanoparticles. Moreover, we will analyze the structure, composition, physical and colloidal properties of the as-synthesized hybrid nanoparticles, as well as the in vitro performance of these nanoparticles as contrast agents in Magnetic Resonance Imaging, Ultrasonography and X-ray imaging techniques. We will also evaluate the citotoxicity of the as synthesized hybrid nanoparticles in normal cells and tumor breast cells lines. Finally, we will target these nanoparticles toward the human epidermal growth factor receptor 2 (HER2) which is overexpressed in breast cancers with a poor prognosis and higher disease recurrence, and we will evaluated in vitro the targeting ability of the obtained anti-HER2-nanoparticles conjugates for HER2+ breast cancer cells.


**Keywords:** ultra-short pulse laser ablation in liquids, laser solution photolysis, synthesis of multimodal nanoparticles, colloidal dispersions, MRI, Ultrasonography, Digital Mammography, X-ray CT
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'The Entertainization of Childhood: An Etiology of Risks and Opportunities' (ENTCHILD).

assistant: **Innovation**

Never before has media entertainment been so abundantly accessible to children. In this project, I propose an entirely new theoretical model to understand entertainment processing and effects. The model enables us to simultaneously investigate: (a) how and why certain types of media entertainment may influence certain children, (b) which children are particularly susceptible to positive, which to negative, and which to both positive and negative entertainment effects, and (c) how children s social environment can maximize positive and minimize negative entertainment effects on children. The project involves a longitudinal panel study among 900 Dutch families. To measure the variables in the model, we will use some well-established survey instruments and neuropsychological tests. We will also employ two less conventional methods (coded media-use diaries and experience sampling methods) that may enhance serendipity in the development of our theory-advancing insights. We will use state-of-the art data-analytic techniques (e.g., multi-level and latent-growth curve modelling) to analyse the data. Although adventurous, this transdisciplinary project, the first in its kind, has great theoretical significance. If the assumptions of my model are supported, it may lead to a fundamental re-evaluation of earlier media-effects theories and research on children. The project will also have tremendous social relevance, not only for parents, but also for programme makers, educators, and the society as a whole. After all, only if we truly understand why, how, and which children are influenced by certain types of media entertainment, are we able to adequately target prevention and intervention strategies at these children.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'FabLab as Entrepreneurship supporting tool for innovation agencies' in the context of a Horizon 2020 call.

assistant: **Objectives**

Fablabs – digital fabrication laboratory – enable creation of new enterprises, offers an environment supporting innovation, and makes prototyping more available and affordable. Nowadays, FabLabs are increasingly being adopted by schools, universities and museums as platforms for project-based, hands-on STEM education. Despite the fact FabLab is great tool supporting technological prototyping and fostering entrepreneurship and innovations, there are only a few innovation agencies in Europe which included this platform in its services for SMEs. Therefore the main aim of the proposed project FABLABIA – Fablab as entrepreneurship supporting tool for innovation agencies is to gather the experiences of innovation agencies who use FabLab as an innovation tool for the benefit of SMEs and to turn it into a codified good practice manual (DOP). The proposed project will have a direct positive impact on SMEs’ capacity in rapid prototyping and product testing. Innovation agencies will help these individuals with market research for their solutions. On the other hand, project will have impact on innovation agencies too. It will lead to improvement in the design and quality of delivered innovation support services. In the process, the FabLab business model and its adaptation to the local conditions, will be explored. This approach will facilitate the uptake of FabLab-based services for SMEs by any interested innovation support agency beyond the consortium members. In this way the project will contribute to raising the level of innovation support provided to SMEs throughout the EU.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Application-level Swarm-based Orchestration Across the Cloud-to-Edge Continuum' to be submitted under Horizon Europe.

assistant: **Abstract**

Collecting and analysing large amounts of data in the Cloud-to-Edge computing continuum raises novel challenges. Processing all this data centrally in cloud data centres is not feasible anymore as transferring large amounts of data to the cloud is time-consuming, expensive, degrade performance and may raise security concerns. Therefore, novel distributed computing paradigms, such as edge and fog computing emerged to support processing data closer to its origin. However, such hyper-distributed systems require fundamentally new methods.  To overcome the limitation of current centralised application management approaches, Swarmhestrate will develop a completely novel decentralised application-level orchestrator, based on the notion of self-organised interdependent Swarms. Application microservices are managed in a dynamic Orchestration Space by decentralised Orchestration Agents, governed by distributed intelligence that provides matchmaking between application requirements and resources, and supports the dynamic self-organisation of Swarms. Knowledge and trust, essential for the operation of the Orchestration Space, will be managed through blockchain-based trusted solutions using methods of Self-Sovereign Identities (SSI) and Distributed Identifiers (DID). End-to-end security of the overall system will be assured by utilising state-of-the-art cryptographic algorithms and privacy preserving data analytics.  Due to the imminent complexity of the decentralised system, novel simulation approaches will be developed to test and optimise system behaviour (e.g., energy efficiency) in the early stages of development. Additionally, the simulator will be further extended into a digital twin running in parallel to the physical system and improving its behaviour with predictive feedba
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Characterisation and distribution of the CEPH bacterial artificial chromosome (BAC) library, a European resource for preparing sequence-ready physical maps' (BAC).

assistant: **Innovation**

- To prepare replicates of the CEPH bacterial artificial chromosome (BAC) genomic library and send these to partners in Italy, Germany and the United Kingdom. - To place about 4,000 sequence tagged sites (STS) and other markers on BAC clones of this library. - To assemble at CEPH a public physical mapping database that contains data concerning these clones featuring the STSs/other markers that they contain.The overall objective of this project is to provide a mapping resource for constructing sequence-ready physical maps by characterising in the European Union the genomic human BAC library developed at the Fondation Jean Dausset- CEPH. The CEPH BAC library contains approximately 200,000 clones obtained by cloning partial BamHI or HindIII partial digests into BAC vector pBeloBAC. The mean insert size of the BAC clones is 126 kb (15% of clones without inserts not included for the estimate), and the mean genome redundancy is estimated at 7.9. The BAC library will be maintained and managed at CEPH. A copy of the library will be sent to each of the partners for characterisation of clones. Four partners will characterise the library by testing the BAC clones for already known and new STS and hybridization based markers with a total of approximately 4,000 markers/STSs. The partners will coordinate efforts to minimise overlap of STSs used to characterise the BAC library. All data accruing from this project will be deposited in a database that CEPH will make publicly available in a timely fashion. This project will deliver a valuable mapping resource, for positional cloning activities and, especially, for sequencing the human genome.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Spray analysis by avanced numerical and experimental techniques' in the context of a Fifth Framework call.

assistant: **Objectives**

Temporal postgraduate position in engineering available Topic: Droplet and Spray Analysis In the chemical engineering research team at the University of Bremen in Germany, a EC funded temporal research position (Marie Curie program fellowship) is available for a postgraduate researcher from the EC or an Associated Member State. The funding duration is one year. The applicant must be 35 years in age or younger. The stay is intended to support the students Ph.D. project at her or his home university. The applicant has the opportunity to participate in a tailored training program in the engineering faculty in agreement with their home university ph.D. Project. The program consists of courses e.g. in multiphase flow, simulation and particle measurement techniques and individually conducted research projects. The research program will allow participation in experimental or numerical spray investigations in a wide area of liquid atomization applications, ranging from water via paint and fuel to molten metal atomization. Fellows will have access to sophisticated laser measurement techniques and high-end computer systems. Main aim of the program is the study of droplet interaction phenomena in sprays. Models will be derived and validated for binary droplet and particle collisions in sprays. Progress in this field is needed for economical and ecological optimization of atomization processes in several application areas, like in automotive and aerospace industry, chemical and materials engineering. Applicants must have a sound background in engineering, specialized in fluid mechanics or chemical engineering. A focus must be on atomization and sprays, either from numerical modeling and simulation or within experimental techniques in dispersed multiphase flows. Further informations
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Digital Forensics in the Historical Humanities: Hanif Kureishi, The Mass Observation Archive, Glyn Moody' (DFitHH) under Horizon 2020.

assistant: **Objectives**

The use of personal computers has fundamentally changed the historical record. “Born digital” documents – private digital archives, legal and public digital repositories, websites and social media content, digital art – have entered the historical record and become part of our shared cultural heritage. Yet few scholars in the historical humanities can preserve, process and analyse these primary sources with the digital forensic methodologies required to maintain evidential integrity, fixity, and authenticity, to recover data, and to draw historically valid conclusions from the digital materiality of the evidence and its preserved technological context. There is a clear need for this situation to change. My project will make that happen.To effect change I will draw on my expertise in born-digital philology and digital forensics to undertake exemplary analysis of born-digital corpora in three distinct UK-based archives that have not been subjected to digital forensic analysis: the archive of the celebrated author Hanif Kureishi at the British Library (BL), the internationally renowned Mass Observation Project Archive (MOPA) based at the University of Sussex (UoS), and the private digital archive of the technology writer and journalist Glyn Moody.Working across these three archives will demonstrate the innovative potential of digital forensic methodologies in the historical humanities and set forensic standards for future research using born-digital archives.This fellowship is, therefore, timely. It will effect real and long lasting change in the historical humanities. It will evolve the state of the art in archive science, philology and historical scholarship. It will create a significant change in engagement with the digital historical record in the historical humanities
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The acquisition of new meanings through novel word learning' (BraveNewWord) under Horizon Europe.

assistant: **Objectives**

We learn new words almost on a daily basis: as adults, a new element is introduced in our vocabulary every other day. With new words, we also learn about new objects and ideas - in most cases new words are not simply additional labels to be applied to familiar objects: they connote meanings that are unknown to the speaker of a language. However, when we experience, as adults, an unfamiliar word, typically its referent is not immediately available in the same context. How then can language, by itself, constitute such a reliable instrument for the acquisition of novel meanings? What do we exploit to induce new meanings on the basis of an unfamiliar sequence of sounds or graphical elements? BraveNewWord addresses these questions in an innovative multidisciplinary perspective, combining cutting-edge proposals from computational linguistics and empirical investigation techniques from experimental psychology and cognitive neuroscience. BraveNewWord posits three main sources for lexically-driven meaning acquisition: linguistic context, word structure, form-meaning mapping. The project advances a computational framework that models these mechanisms through data-driven, psychologically plausible distributional systems trained on examples of natural language usage. The quantitative characterizations and algorithmic definitions offered by these models constitute, in turn, the basis for BraveNewWord large-scale empirical investigation, involving both behavioral (reaction times, mouse-tracking trajectories, diachronic language changes) and neuroscience data (event-related potentials, neuroimaging). With its innovative perspective and advanced computational and empirical approach, BraveNewWord will constitute a non-incremental contribution to understanding how human speakers use new
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Fish value added food chain'.

assistant: **Innovation**

Fish stocks and catches are decreasing and fish is a limited resource. This gives us two main challenges. The first is to get the maximum quantity and quality out of the catch of high value added raw material. The second is to upgrade low value added raw material. The only way to do this is to understand the different processes going on in the raw material at all steps in the food chain from the fish is caught and till it is consumed. This is a cross-boundary research area, combining chemistry, and biochemistry and food technology/engineering with fishing technology and catch handling. The Value fish-training site contains the Department of Biotechnology at NTNU and SINTEF Fisheries and Aquaculture, and the training site offers the possibility to work in a group engaged both in academic research and contract research for the industry. The main area of research in the group is fish chemistry, processing and quality: marine lipids - characterization, stabilization, processing, and fish proteins - solubility, enzymatic activity, functional properties, lipid-protein interactions and changes of the fish raw material during processing. A wide range of methods have been adapted and developed and is currently being used in this work. The laboratories are well equipped with access to advanced analytical instruments such as NMR, Fellows should have basic education in biochemistry as well as experimental skills. A background in physics and mechanical engineering/food technology will also be of interest. Fellows will be able to follow a wide range of courses and be trained in a wide range of analytical methods. Trondheim is rated as the best student town in Norway with cultural events, sports and student societies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Ethical governance of biological and biomedical Research: Chinese-European Co-operation' (BIONET) targeting Sixth Framework.

assistant: **Abstract**

Biological and biomedical research focussing upon the genetic modification of organisms, the genomics of disease susceptibility and on stem cells, and on therapeutic potential of genomic medicine and stem cells technologies, is a national, commercial and scientific priority in China and EU. Such research raises many challenges for ethical governance of scientific and medical practice, many of which have particular relevance to ensuring best practice in EU-China scientific collaborations.BIONETS will set up a sustainable network within and between China and Europe that can map the rationales for and practices of ethical governance of advanced biological and biomedical research in China, provide a platform for the development of comparative research on ethical governance in China and the EU, advance social scientific understanding of key bioethical issues, undertake training of researchers and practitioners in key issues, and inform policy and practice in the ethics of biomedical research in China and the EU with particular relevance for scientific collaboration. Workshops within China will bring together researchers, practitioners, ethicists, social scientists and policy makers to compile and evaluate research and evidence on contemporary policies and practices for the ethical governance of advanced biomedical research, and to explore key issues of the ethical regulation of contemporary biomedical research and to build capacity among participants.A Europe-China database on the ethical governance of research will be created. A European Chinese Expert Group on ethical governance of contemporary biomedical research will be established. The network will facilitate exchanges of personnel, research findings between Europe and China. Capacity building in both Europe and China i