RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Enhancing production efficiency through ultra-light high performances machine tools', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

The project aims at solving this problem of Europ. Machine tools (MT) builders: reduce the weight of machine structures while maintaining the same cost (compare to conventional ones) and increasing their performances in terms of speed, accel, accuracy The goals will be reached by using innovative high stiffness, light weight materials, not only considering their inherent structural properties but also their space location, joint interfaces, related process technique. The innovative aspects of ULMAT are related to comprehensive and integrated material-product-process approach considering the optimal use of available material (Al-alloy, steel sandwich, High Strain Steel) together with the optimal application and low-cost processing of innovative materials(Al -honeycomb, fibres-polymer matrix composite, ultra-light alloy) .The results are:3 ultra-light machine tools demonstrators.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Vibronic control of organic electronic devices' (VIBCONTROL).

assistant: **Concept**

Organic electronics (OE) is an expanding research field that exploits the electronic functionalities of organic molecules to make them robust and cost-efficient building blocks for future electronic devices. Due to the ‘soft’ character of organic materials, their electronic properties are defined by vibronic coupling (VC) phenomena which are a result of the interaction between electron and nuclear dynamics of the molecule.This research program aims to unlock a new direction of experimental studies investigating and exploiting VC in OE devices by using optical control of nuclear motion.The growing awareness that VC underlies diverse phenomena from physics to biology stimulates a broad interdisciplinary effort to address this issue. However, in the field of OE, the lack of synergy between device and optical studies holds the potential functionality offered by VC effects from being attained. In 2012, I proposed a direct route to control the performance of OE devices by optically switching the vibronic states of the molecules. Though this work came specifically in connection with organic photovoltaics, it provides the starting point for a more fundamental and broad reaching of VC phenomena. The proposed research program will use this opportunity. I will apply state-of-the-art developments in infrared light shaping to create a well-defined coherent superposition of molecular vibrational motions inside devices and study their influence on electron dynamics with device-specific spectroscopic techniques.This approach combines recent advances in ultrafast spectroscopy and OE to extend our fundamental understanding of molecular charge transport. Our methodology will become a tool for elucidating current pathways in organic nanodevices and offer access to non-equilibrium phenomena
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Small Air Transport - Roadmap' (SAT-RDMP), addressing dissemination and exploitation.

assistant: **Impact**

The Small Air Transport (SAT) focuses on the new mode affordable, accessible, energy effective component of Air Transport System. It fills niche between Surface and Scheduled Air Transport.This future SAT system will provide a wide choice of transportation  mode - and the wider use of small aircraft, served by small airports, to create access to more communities in less time.The goal of the proposal is to demonstrate contributing to an improved understanding of the role that small-size aircraft operating on scheduled or non-scheduled flights can play as a component of the Air Transport System to satisfy the needs of transportation in regions where transport networks are underdeveloped.Main issues of the SAT-Rdmp Study (CSA-SA) proposal are:• Definition of a common vision of the small aircraft transport system for inter-regional mobility through the identification of the corresponding requirements. The requirements will identify the technology needs and regulatory issues to be addressed.• Definition of a business case compliant to the identified requirements which describes the relations among all the system’s components.• Assessment of current capabilities versus the ATS demand, collection of previous results  and involvement of  the stakeholders in Europe among all actors (manufacturers, research establishment, EASA, airspace users, infrastructure providers, airport managers, small aircraft service providers).• Definition of a roadmap to fill the technology/regulatory/operative gaps in order to fulfill the requirements considering the current capabilities. Identification of dissemination actions and establishment of a network of stakeholders.• Assessment of risks and benefits of the identified new system’s concept.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Forgotten Dreams of Mao’s Ousted Class: An Intimate Ethnography on how the Chinese Intelligentsia Survived the Mao Zedong Era' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

This project combines history, anthropology and politics to complicate official representations of Chinese history told by the current regime of power. Starting from my own family history, which sits at the core of this research, Forgotten Dreams of Mao’s Ousted Class is guided by the stories of my Chinese grandfather and Finnish grandmother as a mixed-racial couple of the intelligentsia class at a time of political transformation when an imagined socialist future seemed within grasp. In a novel enquiry to re-conceptualize how collective memory is transmitted, this first ever state-of-the-art ethnographic project documents and analyses silenced stories of grievous loss and trauma of the Chinese educated elite to reconsider what lurks beneath the nation’s autocratically monitored socialist dream that holds post-Mao Chinese society together. My three-year postdoctoral project is an intimate ethnography that bridges ethnography and biography to offer a new methodological approach to studying the transmission of loss by state violence in contemporary history. Professor Alisse Waterston, the supervisor for the outgoing phase at City University of New York (CUNY), and Professor Maarit Forde, the supervisor for the return phase at the University of Helsinki (UH), will support my work and mentor me to deliver an innovative and novel intimate ethnography monograph that combines methodology and theory; politics and ethnography; the personal and the historic.


**Keywords:** intimate ethnography, ethnography, social history, Mao Zedong rule, intelligentsia, China, political violence, memory, recollection
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Small molecule stabilizers of 14-3-3 Protein-Protein Interactions as novel drugs in cancer and neurodegenerative diseases'.

assistant: **Concept**

The objective of the application is the development and characterization of small molecule stabilizers of protein-protein interactions (“Molecular Glues”) as a novel class of biological tool compounds and potential therapeutic drugs for the treatment of cancer as well as Alzheimer’s and Parkinson’s Disease, respectively. As biological targets we work on 14-3-3 proteins, an important class of adapter proteins that regulate a multitude of enzymes and proteins involved in the development of cancer and neurodegenerative diseases. 14-3-3 protein-protein interactions relevant in different cancers are Raf1 and YAP/TAZ. In Alzheimer’s and Parkinson’s Disease the interaction of 14-3-3 proteins with AICD and α-Synuclein are of potential therapeutic interest.The proposed project is based on the innovative approach to develop small molecules that bind selectively to the interaction surface of specific disease-related protein complexes thereby stabilizing their interaction which might lead to a beneficial therapeutic effect. This approach is complementary to today’s strategy of developing inhibitors that target the active site of single enzymes and opens new possibilities to address “undrugable targets”. In fact, small molecule stabilizers of protein-protein-interactions have the potential to deliver a target-specific, target-oriented and more efficient modulation of the protein function than “classical” inhibitors. In this application, we propose two projects identifying and optimizing small molecules stabilizing 14-3-3 interactions with:1.The cancer-relevant proteins Raf and YAP/TAZ2.The Alzheimer’s and Parkinson’s disease-relevant proteins AICD and α-Synuclein.By stabilizing these protein-protein interactions the biological functions and biochemical properties like biochemical ac
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'European Sustainable Electricity; Comprehensive Analysis of Future European Demand and Generation of European Electricity and its Security of Supply' (EUSUSTEL) under Sixth Framework.

assistant: **Objectives**

The proposed project aims at providing a fully consistent framework for a secure electricity provision, that is at the same time environmentally friendly and affordable. The conclusions of the project must result in policy recommendations for the member states and the Commission. The methodology used mixes two directions of analysis. In a first (horizontal) one, the existing electricity systems of the 25 EU countries are analysed and national policy choices and future projections are studied. Next, vertically then, a subject-wise treatment is considered, whereby both the demand side as well as the supply side technologies and system integration are treated.Furthermore, the regulatory and liberalised market framework for an integrated European electricity market is carefully examined and appraised. Based on these analyses, it is then in a combined approach attempted to summarise the 'static' overall social cost (private cost plus external cost) for electricity generation. Subsequently, these cost figures are used as input in carefully screened simulation models in order to perform some well-defined and contrasting scenarios, but in line with the regulatory framework of the energy market. From these results, it must be possible to obtain the 'most optimal solution' (from an economic-effectiveness point of view -including environmental burdens) for the electricity provision in Europe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The Molecular Mechanisms of Heart Regeneration' (CARDIOGEN) targeting Seventh Framework.

assistant: **Abstract**

Adult zebrafish are capable of completely regenerating their heart after an extensive insult. Previously, we determined that the regenerated myocardium was produced by the proliferation of existing cardiomyocytes and not, as had previously been reported, by stem/progenitor cells. Analysis of regenerating hearts shows that soon after injury cardiomyocytes detach from one another and dedifferentiate, disassembling their sarcomeric structure in the process. In situ and microarray analysis indicate that dynamic changes in gene expression are also associated with heart regeneration. At present only handful of genes have been directly linked to heart regeneration in zebrafish. Our main objective is to expand this small list and thus provide candidates which can subsequently be manipulated in mammals. To determine suitable target genes, we will make use of the substantial microarray data generated from studying heart regeneration in zebrafish. Importantly, this data has revealed that certain genes shown to be up-regulated during zebrafish heart regeneration have previously been shown to positively regulate cardiomyocyte proliferation in mammalian models.  These findings not only indicate that zebrafish and mammals share similar genetic mechanisms as far as regulating cardiomyocyte proliferation but also verify that the data represented in the microarrays contains positive candidate genes. Once candidates have been selected and confirmed in our zebrafish model system, we will begin testing these in vitro in mammalian cardiomyocytes before creating transgenic mouse models to determine whether they are capable of inducing myocardial regeneration following cardiac ischemia.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'InnOvative ArtiFicial IntelligencE methodologIes for monitoRing and maintaining large scale complex infrastrUctures and obtaining greener, more Resilient and smart societies' under Horizon Europe.

assistant: **Concept**

Over the past 2 decades, the use of artificial intelligence (AI) has exponentially increased toward complete automation of structural inspection and assessment tasks. This trend will continue to rise in image processing as unmanned aerial systems (UAS) and the internet of things (IoT) markets are expected to expand at a compound annual growth rate of 57.5% and 26%, respectively, from 2021 to 2028.  It is generally accepted that AI will drive the next revolution in autonomous inspection and health monitoring of civil infrastructure. The possibility of complete automation of the inspection process resulted in a lot of attention from the scientific community leading to a plethora of research in this area.  FOURIER intends to establish a network of individual research projects working towards breaking through and innovative system state monitoring (stm) techniques – via the use of AI for large-scale autonomous systemic monitoring, inspection and proactive testing including respective explicit identification of information gaps and uncertainties (information quality) of Complex Engineering Systems to improve their resilience against failures, accidents, sabotage, disruptions and disasters.  The objective of FOURIER is to offer innovative research training as well as knowledge exchange opportunities for Doctoral Candidates (DCs) through cross-border and cross-sector mobility for future growth in Europe. FOURIER is an inter/multi-disciplinary and intersectoral programme as it includes seven academic partners, three research centers and seven private companies and two end users from seven different European countries.


**Keywords:** Resilience; Structural Health monitoring; Artificial Intelligence; Augmented reality; damage detection;
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Optimisation of Tidal energy Converter Arrays' (OpTiCA) targeting Horizon 2020.

assistant: **Abstract**

As technology readiness level of Tidal Energy Converters (TECs) increases, moving from prototype demonstration to commercialisation, research efforts are focusing on TEC arrays layout optimisation to reduce costs and become competitive in comparison with other energy systems. Even though there are several prototypes of different scales that have been tested on the last years (mostly under controlled conditions) there is limited data on deployments in real conditions which negatively affects the accurate formulation of constrained problems on array schemes resulting on incomplete layout optimisation models. This project aims to provide a significant contribution towards the understanding of (a) the effects of TECs interactions with the environment; (b) the capabilities and limitations of common strategies used for the numerical modelling of TECs; and (c) how to mathematically formulate optimisation models to solve the TEC array layout problem considering technical, socio-economic and environmental constraints. From the methodology point of view, constraint optimisation models will be mathematically formulated considering ocean energy protocols, data collected from in-field measurements of prototypes tested in real environments and with surrogates built from validated numerical simulations. The outcomes of the project will contribute to improve common guidelines and standards for licensing tidal energy projects and de-risk financial investment. The Experienced Researcher (ER) will emerge from the project with an in-depth knowledge of tidal stream energy, training in mathematical optimisation and on new skills in data collection, increased competence on numerical modelling, and strong skills in research project management and coordination. This will grant him the capacity
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Decipher how mRNAs are captured at specific subcellular locations to support local translation in neurons' (2021-2027).

assistant: **Innovation**

Brain function requires precise regulation of the neuronal proteome which involves localizing thousands of mRNAs to neurites, where specific subsets are translated at the required subcellular locations. Although local translation is well-established, the mechanisms that ensure the capture and translation of specific mRNAs at the correct subcellular location remain elusive. A better understanding of this process is urgent since dysregulation of mRNA localization and translation is emerging as a key pathological event in neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS).In RNA.ORG, I aim to define, at a molecular level, how the coordination between mRNA transport, capture and local translation occurs to support neuronal function.Recent work from my lab and others has shown that multiple organelles interact with mRNA and translational machinery. This raises the exciting possibility that organelle interactions coordinate mRNA distribution, local capture and selective translation. I have developed tools to visualize and manipulate organelle position and contacts at nanoscale resolution. Here, I will leverage these tools and directly control mRNA positioning to elucidate the importance of mRNA capture in neuronal function and intervene in its dysregulation in ALS.In combination with live-cell and super-resolution imaging, RNA-sequencing and proteomics, this project will address the following key objectives:1) Resolve the subcellular distribution and dynamics of neuronal organelle-mRNA contacts2) Unravel the functions of organelle-mediated mRNA capture at specific subcellular locations3) Determine the role of dysregulated mRNA capture in amyotrophic lateral sclerosisRNA.ORG will elucidate novel mechanisms on the subcellular capture and translation of speci
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Combination of Supercritical Carbon Dioxide and Water for foaming of polymers' to be submitted under Horizon 2020.

assistant: **Abstract**

Siphony is a disruptive project created from a Breakthrough Materials Coalition between CellMat Laboratories and Dr. Danilo Cantero. This is a multidisciplinary venture involving the Physics and Chemistry of polymers and the Thermodynamics and Process Engineering of Supercritical Fluids. Sub and Supercritical water will be annex to the use of carbon dioxide in the foaming of Polymethyl methacrylate. The innovative and never seen before addition of sub and supercritical water will create benefits in the chemical swelling of the polymer and the addition of thermodynamic energy of explosion, approximately 5-6 times more than carbon dioxide itself. With this, it is expected to achieve the extra hit of power and material softening to reach an outstanding nano cellular polymer of very low density (10 times density reduction compared to initial polymer) and high pores density (>1013 pores/cm3). This kind of materials has outstanding properties as insulators (thermal and acoustic) in many fields of the industry. This proposed invention by employing Siphony process will create an exceptional rated polymer that will revolutionize the insulation industry by dropping insulators weight and increasing the heat transference resistant. Siphony also involves the application of the revolutionary concept invented by Danilo Cantero: the Continuous Sudden Expansion Reactor. The application of this technology to the foaming process of PMMA will bring unconventional properties to the product as well as to the process of foaming. This technology has demonstrated accurate control of residence time and temperature in a continuous mode. In this project, the technology will be redesigned to maximize the water/carbon dioxide dissolution in PMMA and the water/carbon dioxide expansion by sudden decom