RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Patterned optical activation of retinal ganglion cells' to be submitted under Seventh Framework.

assistant: **Abstract**

Direct activation of retinal ganglion cells is a promising approach for treating blindness resulting from degenerative diseases of the outer retina. Current neuro-retinal stimulation interfaces being developed use electrical currents from micro-electrode arrays, but future systems could use light patterns to create spatio-temporally complex activity patterns. We will develop, optimize and test different concepts allowing patterned optical stimulation of large populations of retinal ganglion cells based on emerging methods for light-based neuro-stimulation, including glutamate uncaging and ectopic expression of the light-sensitive ion channel Channelrhodopsin II. A series of in vitro and in vivo experiments will examine basic questions regarding the efficacy and safety of this general approach. Our experiments will define the major engineering requirements and constraints towards the development of a light-based approach for restoring vision in individuals with outer-retinal degenerative diseases.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Polymathy and Interdisciplinarity in Premodern Islamic Epistemic Cultures' (KNOW) under Horizon Europe.

assistant: **Objectives**

KNOW is the first comprehensive study of polymathy and interdisciplinarity in premodern Islam. The project sets out to write a history of knowledge that takes the interaction between disciplines as its primary subject. The project’s historical framework is the post-formative period, 1200-1800 CE, which saw the rise of new institutions of learning, the proliferation of libraries, the formation and integration of disciplines and curricular texts, and an increase in academic travel, facilitating interdisciplinary cooperation, competition and conflict. Despite its significance, our knowledge of this period remains rudimentary. The project promises to transform our understanding of the intellectual dynamics of this period by applying the lens of polymathy and interdisciplinarity. Previous scholarship has focused on intellectual products (i.e., doctrines and texts) and has tended to project our contemporary disciplinary divisions onto the premodern period (e.g., humanities v. sciences; religious v. secular). This project departs from these approaches by focusing on epistemic processes and practices rather than products and artefacts. To do so, the project tests three research hypotheses: (1) cultural and intellectual vibrancy of the premodern period is evident in the interaction between disciplines, (2) madrasa education and hospital culture produced an interdisciplinary space, (3) interdisciplinary practices created a common scholarly language. The project’s interdisciplinary methodology draws on the history of science, interdisciplinary studies and polymathy studies. The PI will be supported by an interdisciplinary team of three postdoctoral researchers covering, together, the intersections between philology, theology, exegesis, law, medicine, logic, algebra, and geometry i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Remotely Operated CBRNe Scene Assessment  Forensic Examination'.

assistant: **Objectives**

The overall goal of ROCSAFE is to fundamentally change how CBRNe events are assessed, in order to and ensure the safety of crime scene investigators by reducing the need for them to enter high-risk scenes when they have to determine the nature of threats and gather forensics. For this, ROCSAFE will make use of cost-effective modern remotely-controlled robotic air and ground vehicles (RAVs/RGVs) that are designed for use in rain, wind, and challenging ground surfaces and obstacles. First, RAVs will assess the scene. These will have cameras and can carry an array of innovative new high-performance and rugged miniaturised sensor systems for RN, chemical and biological threats.To reduce the scene commander’s cognitive load, ROCSAFE will include new Central Decision Management software and a Command Centre. All images and data will be streamed to this, where it will be analysed and displayed on a sophisticated and intuitive interface with maps and video, showing results of analytics and giving readings geographical context. This will enable the scene commander to assess the nature of threats, develop an Action Plan and an Evidence Plan, supported as needed by the Central Decision Management. It will also assist in coordinating sensors and mobile units. Its data analytics will provide fusion of multiple sensor data sources, to allow probabilistic reasoning about the most likely threats and likely locations of epicentres.After the scene is assessed, RGVs will be dispatched to collect forensic material/evidence, with automatically-optimised routes to avoid hazards. They will have innovative new equipment for forensics collection that will automate best practices. Forensic material will be collected, bagged, tagged, documented, and stored by the RGV.Thus, ROCSAFE will ensure tha
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Requirement/Benefit Definition Study leading to 4-D Meteorological Data Bases linked across Europe' (4MIDABLE).

assistant: **Concept**

The objective of the 4MIDABLE project is to specify the requirements for the meteorological aspects of operational prediction of future aircraft position in four dimensions. Both the short term prediction (20 minutes ahead) and the longer term (including air traffic flow management issues) will be addressed. In the former wind is the prime issue with effects of anti-icing as a secondary issue. In the latter fog and severe convective clouds (commonly, but not exclusively, cumulonimbus) are major considerations. In addition other hazardous meteorological phenomena have to be addressed. In a European context all these mechanisms for causing low level wind shear will be given comparable priority.The project will therefore concentrate on better quantifying the state of the art of forecasting these various phenomena and evaluate the expected improvements, obtaining a better specification for the requirements for these forecasts, obtaining a specification of the sensors required to facilitate forecasts of the required accuracy, quantifying the effect of wind variability on 4-dimensional navigation, exploiting complementary characteristics of different sensors for improved cumulonimbus detection and nowcasting, defining new lines of action for RTD in this area. %
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'A low emission spray drying and microencapsulation process for improved environmental performance.' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Spray drying is used to remove moisture and turn the product into a powder for storage or convenience. It is also used for micro encapsulation to give controlled release and other functions. In the usual open cycle configuration, spray dryers vent extracted water vapour directly to the open air, often with odours and particles, creating air pollution in the locality. Closed cycle spray dryers are operated in specialist applications but a general, low cost closed cycle spray drying technology is not in use. This project will develop a closed cycle spray dryer and demonstrate it in general drying and micro encapsulation applications. Novel technologies for dehumidification, heat recovery and removal of volatiles will be investigated to meet the objective of a low cost process, to replace existing open cycle spray dryers. This will have important benefits for Sees and larger end users in terms of reduced emissions, giving greater flexibility in the sitting of their operations.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Genotoxicity prediction by means of QSAR methods for regulatory purposes', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The concern to protect human health and the environment has prompted significant changes in EU regulation on chemicalsubstances. The European Chemicals Agency (ECHA) plays the role in implementing the Registration, Evaluation,Authorization and Restriction of Chemicals (REACH) legislation, that requires industry to evaluate the toxicity of chemicalsubstances that are in use but have never been subjected to regulatory testing.REACH regulation has also raised strong criticism and concern from society and industrials because of ethical and economicreasons. The toxicity evaluation of chemicals requires costly, time-consuming and ethically questionable animalexperiments. As consequence, this European regulation promotes scientific innovation and encourages the use of resultsgenerated by alternative methods, including especially non-testing methods (NTMs), also referred to as in silico tools.Among them, “Quantitative Structure-Activity Relationships” (QSAR) methods are one of the most recognized machinelearning methods in drug design, toxicology, industrial and environmental chemistry. Nowadays, they can be included inintegrated testing strategies (ITS), to provide information for hazard and risk assessment, classification and labelling.We propose the development of an ensemble of QSAR predictive models for several parameters related with the differentkinds of genotoxicity damage. These chemoinformatic will be implemented on a proprietary computational technologicalplatform. Particular attention will be also payed to the generation of models for nanomaterials, taking into account their highand growing impact nowadays on industry in general.The QSAR models and integration algorithms will be characterized bytheir reliability, and will be developed according to the rules set out
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'A molecular approach to treat diabetes mellitus onset dependent coronaropathy' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

In Europe, 59 million patients suffer from diabetes mellitus with health costs of 142 billion Euros per year. As one of the most challenging consequences, diabetes inflicts cardiovascular disease leading to cardiomyopathy and cardiac death. A global, current aim lies in preventing cardiac complications in patients with diabetes mellitus.In pathogenesis of diabetic cardiomyopathy, the role of microvascular processes remains largely elusive; my proposal aims at solving this key question – an impossible mission so far. As attractive therapeutic concept and overall objective, the present proposal aims at exploiting microvascular mechanisms for preventing and treating diabetic cardiomyopathy.I will study a novel, unique transgenic pig model of diabetes mellitus combined with advanced, patient compatible molecular imaging. We pioneered distinct genetic manipulations in pigs, including adeno-associated viral vectors (AAV) for microvessel stabilization as well as AAV-based CrispR/Cas9 transduction for in vivo genome editing. Using this cutting edge technology, I could decipher an important role for microvascular capillary rarefaction in the development of diabetic cardiomyopathy in my previous work. In the present proposal, I aim at determining1.novel, microvascular-focused therapeutic targets for diabetic cardiomyopathy2.the effect of reduced microvascular damage on myocardial function in diabetes, both in the absence and presence of ischemia.My approach will implement targeting microvessels as new paradigm for treating diabetic cardiomyopathy. I will identify novel therapeutic targets for tailored drug development by industry and academia. My planned work will improve the success rate of clinical trials for the benefit of patients suffering diabetic cardiomyopathy and putativ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'OpenLab: extending FIRE testbeds and tools' (OpenLab).

assistant: **Concept**

Experimentally-driven research is key to success in exploring the possible futures of the Internet. An open, general-purpose, shared experimental facility, both large-scale and sustainable, is essential for European industry and academia to innovate today and assess the performance of their solutions. OpenLab brings together the essential ingredients for such a facility. We extend early prototypes of testbeds, middleware, and measurement tools so as to provide more efficient and flexible support for a diverse set of experimental applications and protocols. The prototypes include a set of demonstrably successful testbeds:  PlanetLab Europe, with its 153 partner/user institutions across Europe; the NITOS and w-iLab.t wireless testbeds; two IMS (IP Multimedia Subsystem) telco testbeds for exploring merged media distribution; a green networking testbed; the ETOMIC high precision network measurement testbed; and the HEN emulation testbed. Associated with these testbeds are similarly successful control- and experimental-plane software. OpenLab advances these prototypes with key enhancements in the areas of mobility, wireless, monitoring, domain interconnections, and the integration of new technologies such as OpenFlow. These enhancements will be transparent to existing users of each testbed, while opening up a diversity of new experiments that users can perform, extending from wired and wireless media distribution to distributed and autonomous management of new social interactions and localized services, going far beyond what can be tested on the current Internet. OpenLab results will advance the goal of a unified Future Internet Research and Experimentation (FIRE) facility. In addition, OpenLab can provide models for the Future Internet Public Private Partnership (FI-PPP). F
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Deployment And engagement of Resources and citizens for European Emergency Response' under Horizon Europe.

assistant: **Concept**

The DARE (Deployment And engagement of Resources and citizens for European Emergency Response) project aims to enhance Europe’s capability to respond to large-scale cross-country disasters, focusing on interoperability and information sharing. By addressing the challenges posed by varied national response systems, equipment, training, and procedures, DARE targets four main gaps: operational standardization, command structure interoperability, digital tool integration, and citizen engagement.The project seeks to harmonize emergency response across European countries by creating guidelines for both technical and command-level procedures. This involves comparing and mapping Standard Operating Procedures (SOPs) to identify commonalities and improve interoperability. DARE will develop an open-source Dashboard that integrates real-time data from diverse sources, including hazard monitoring systems, local authorities, and citizen inputs. This platform will support situational awareness, enhance communication between command centers and field responders, and provide a public-facing layer for citizen engagement, including tasking volunteers.To achieve these goals, DARE involves numerous European partners, including research institutions, emergency services, NGOs, and universities, collaborating to test harmonized procedures and training modules through workshops and field exercises. The Dashboard will support standardized information exchange, enhancing cross-country deployments and assisting local commanders with up-to-date hazard and resource information. By leveraging artificial intelligence, it will facilitate multilingual communication and engage citizens, enabling real-time volunteer mobilization and feedback loops with communities during crises. Through structured trainin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Multifunctional Graphene by means of a Chemical Approach' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The aim of MultiGRAPHCHEM is to undertake an extensive scientific program on the synthesis and characterization of a broad range of Multifunctional Graphene Systems. The multifunctionality will arise from the combination of -and the interplay between- the outstanding Graphene properties with those arising from the functionalization, which will be magnetic, optical, electrochemical and/or catalytic.The main objectives of the project are: i) the synthesis and characterization of several high-quality soluble functionalized graphene materials, having different organic functional molecules; ii) the tuning of the magnetoresistance by means of chemical design, introducing electronically active molecules and controlling the surface functionalization; iii) the photoswitching of the electronic properties such as electrical conductivity by covalent azobenzene derivatization; iv) the development and characterization of thin films of defective-free graphene through molecular recognition of functionalized graphenes; and v) the synthesis of magnetic nanoparticles/magnetic clusters-graphene hybrids for the room temperature tuning of magnetic properties on surfaces.In this sense, the project will require a multidisciplinary work, involving Organic and Supramolecular chemistry, essential for the succesful derivatization of the ubiquitous 2D material, and Physics, which will be employed in the study of the properties exhibited by these systems. As a final result, the project target will allow for an advanced chemical functionalization of G, an understanding of its physical properties and of the mechanisms underlying the proposed switching phenomena, which would lead toward the development of more advanced G-based devices.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Fully Electrically Controlled Ultra-fast Chiral Light Handedness Switching in Organic Light-Emitting Devices' (FastE-Chiral).

assistant: **Innovation**

Chiral light, with a rotating electromagnetic field, is revolutionizing optoelectronics, quantum optics, and spintronics. This unique light delivers either 'left' or 'right' optical information based on its polarization, similar to how alternating electrical signals transfer sound and images. Despite centuries since the discovery of chiral light, achieving electrical modulation of its handedness in light-emitting devices remains a significant challenge.Traditional methods of switching chiral emission handedness, e.g., inverting material stereochemistry or mechanically rotating optical filters, encounter practical limitations: complicated fabrication and slow switching speeds. However, electrical modulation of light handedness simplifies manufacturing processes, and enable in-situ controllability. This allows for not only the switching of handedness but also capability to do so at high frequencies.My approach departs from prior research. Instead of focusing on emitters, I will investigate the largely overlooked molecular environment of these emitters—the host materials. These materials account for ~90% of host-emitter blends and significantly influence the transport properties of organic light-emitting devices, but their role has been surprisingly neglected in previous research.My objective is to create a chiral environment for emitters using chiral host materials, thereby manipulating electron behavior. Such transport behavior will ‘polarize’ the entire recombination processes, making the chiral emission handedness dependent on current flows. Integrating these materials into a new chiral organic light-emitting transistor, the goal is to achieve ultra-fast handedness switching of highly polarized chiral emission within a single device.Despite notable challenges, creating