RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Blocking BAFF signaling to treat Proliferative Kidney Disease (PKD) in trout'.

assistant: **Objectives**

PKDControl is aimed at validating the use of a recombinant protein to reduce the pathology and mortality produced by proliferative kidney disease (PKD) in salmonids. PKD is caused by the myxozoan parasite Tetracapsuloides bryosalmonae that affects both cultured and wild salmonids in North America and Europe. It can eventually lead to mortalities of up to 90%, generating great economic loses every year to the aquaculture industry. This problem may be aggravated by global warming since the incidence and severity of PKD are exacerbated by rising temperatures.During my ERC Consolidator Grant we have demonstrated that the cytokine BAFF (B cell activating factor) mediates the dysregulation of diverse B cell subsets present in the kidney during PKD. We have shown that the intramuscular injection of a plasmid coding for the extracellular domain of BAFF receptor (BAFF-R) led to secretion of this truncated BAFF-R (tBAFF-R) that, in turn sequestered circulating BAFF, blocking BAFF signalling. Preliminary field tests in Spain and USA demonstrated the potential of this approach in reducing the pathology and mortality of the infected stocks. In this project, we will recombinantly produce tBAFF-R in yeast to facilitate its uptake by the industry and test its bioactivity in both lab and field experiments. In parallel to these technical activities, we will reinforce the IPR position (based on a PCT - international - patent application that has received a very positive patentability report by the patent office). We will also design a long-term IPR strategy and develop a knowledge transfer strategy through the recently initiated collaboration with a fish health management company, willing to reach commercialization of tBAFF-R under a license and to contribute with their own funds to the a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Democracy under Threat: How Education can Save it' (DEMED) under Horizon 2020.

assistant: **Objectives**

We are currently witnessing an unprecedented rise of authoritarian leaders, backed by popular support, who defy democracy. Challenging existing paradigms and an elite-focused literature, DEMED will take an individual-level perspective to study the causes of democratic backsliding and identify solutions to build more resilient democratic societies. Thereby, DEMED will have a transformative effect on the study of democracies and autocracies as well as the dynamics between the two.  DEMED is a ground-breaking project that transforms our knowledge about the process of democratisation and backsliding. Work packages (WP) are divided along four objectives: 1) Establish causes of democratic backsliding, focusing on the role of indoctrination; 2) Demonstrate the effects of indoctrination on democratic political cultures and democratic survival; 3) Identify solutions to prevent democratic recessions through innovative online civic education programmes; and 4) provide a new theoretical and empirically validated paradigm to lead to more stable democracies.   WP1 develops the first unifying theoretical framework of societal drivers predicting democratic (in)stability. Based on this theoretical and conceptual work, WP1 creates the first-ever global dataset on strategies of indoctrination by 180 countries from 1900 to today. WP2 uses cutting-edge methods to test for the first time how these educational drivers create democratic and authoritarian political cultures. This quantitative approach will be complemented with original qualitative data. Finally, WP3 uses pioneering online randomised experiments to test the impact of newly developed civic education interventions to promote democracy.   This is an ambitious research agenda, with theoretical and methodological innovations. DEMED r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Twin to twin transfusion syndrome and monochorionic twinning european network'.

assistant: **Concept**

Monochorionic (MC) twins are rare (3/1,000) but have a much higher risk of perinatal death or neurological sequelae than dichorionic twins or singleton pregnancies. Furthermore, 15 % of MC twin gestations complicate with the Twin-to-twin transfusion syndrome (TTS). The cause for this poorer outcome lies in the ever-present vascular connections in the MC placentas. Although MC status can be identified early in pregnancy, this is often not done due to unawareness of its consequences. There are neither data to offer guidance on how to follow up these high-risk pregnancies, nor how to treat TTS. Clinical studies are proposed to improve pathophysiologic insight, such as the determination of the natural history of early-diagnosed MC twins and the exact risk for developing TTS. We will evaluate the incidence and nature of long-term sequelae in survivors of TTS. A prospective study will be conducted to determine which is the best therapy for TTS, neurological morbidity in survivors being the primary variable. In our study patients we will determine the placental angioarchitecture, correlate it to clinical pregnancy outcome and use this information to establish a computer model for the disease. In addition instrumental innovations are proposed to improve therapy of TTS and abnormal MC twin pregnancy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Harmless Respiration for Intensive Care Patients decreasing mortality and shortening stays – including COVID-19 patients' (Jane), addressing dissemination and exploitation.

assistant: **Impact**

The current outbreak of COVID-19 is incisively pointing towards the importance of optimal mechanical ventilation in Intensive Care. Improved mechanical ventilation saves lives. Last year, we have seen multiple cases in which our mechanical ventilator suited only for the Operating Room (OR), was used off-label in ICU to ventilate severely lung-ill patients. Doctors claim patients would have died if our device would not have been used. These case reports are supported by more fundamental evidence published in March 2020: in-vivo studies on pigs having similar lung-illness as with the current COVID-19 outbreak (called Acute Respiratory Distress Syndrome) have shown superior result with our disruptive ventilation method, called FCV®. Half of all patients on higher grade Intensive Care Units need mechanical ventilation. However, current ventilation methods are known to damage the lungs in these vulnerable patients. This significantly prolongs ICU stay and increases mortality. The damages relate to the passive expiratory phase during mechanical respiration, which is fast and uncontrolled resulting in shear stress and collapse of the distal lung parts. Prolonged ventilation then initiates inflammatory responses in the lungs. We have developed a new ventilation method controlling the expiration, preventing lung damage.In 2017 our innovative OR ventilator (Evone) was brought to the market. Having performed over 1,000 OR patient cases and 5 small clinical studies till date, clear superior ventilation and improved lung mechanics has been shown. However, the largest unmet medical need related to ventilation is on ICU. The objective of this proposal is to bring this superior ventilation technology to ICUs in Europe, the Middle East and in 2nd phase the USA and by that, lower ICU mor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Implicit Learning in Specific Developmental Disorders'.

assistant: **Concept**

This project proposes to explore implicit learning among children with developmental disorders. Implicit learning is a process whereby we learn about regularities in our environment, including written text, without conscious awareness or effort to learn. While specific cognitive abilities such as phonology and memory have been extensively explored more global, fundamental learning abilities are rarely studied: there is a significant gap in the study of implicit learning despite suggestions that learning becomes more implicit in nature after explicit instruction takes place. It is argued that impairments in the mechanisms of implicit learning could mediate selective weaknesses in other cognitive processes such as reading and numeracy. The present project puts this argument under test in a series of behavioral and neurobiological studies of implicit learning in typical and atypical young populations, namely children with dyslexia and dyscalculia. This way, the nature of the project becomes twofold: first, it will examine fundamental implicit learning abilities in children with developmental disorders; the exploration of potential implicit learning difficulties coupled with well-studied specific deficits may offer the ground for a better understanding of such disorders. Second, it provides the first neuroimaging data on young children to generate functional phenotypes to predict individual differences in implicit learning. Most importantly, the findings will be used to create innovative, culture-free and language-free interventions that enhance children’s learning potential and improve their experience of schooling across Europe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Resounding Ships: Sound and Music of Sacred Sea Travel between Venice and Jerusalem (c. 1450-1650)', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The maritime route between Venice and Jerusalem testified to an incredible exchange of thousands of people in the fifteenth and sixteenth centuries. Among these were pilgrimages, which gathered transregional, multiethnic and multireligious communities, brought together through sound in spite of their language, cultural and religious differences. Pilgrims’ diaries narrate a sense of community that was initiated and preserved by sound phenomena such as noise and silence, sonic practices such as sounding trumpets or whistles, and various music practices, including chanting. In the current time, marked by intensifying interethnic, intercultural and religious tensions, my project advocates for and fosters multicultural cohesion within modern society.Despite being naturally prominent in general early modern travel, sound’s meaning for the travelling community remains under-researched, and has rarely been considered within in-between, transitional spaces of mobility and cultural exchange. SOUNDSHIP offers a new, far more more nuanced understanding of sound perception in early modern communities, their formation and preservation, and will be the first systematic study of sound and music in early modern travel. It will do so through an innovative application of sound studies, auditory history, historical musicology, religious studies, and performance practice research on pilgrims’ narratives, philosophical, music, medical treatises, and music practices.With a strong track record in assessing music historiographies through sound studies, Dr Cugelj will work with Prof James Mansell, an international expert for sound methodology and innovative practices in sound research at the University of Nottingham. The MSCA will establish Dr Cugelj as an independent sound scholar with internat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Brain Development and Cognition in Human Infants' (1998-2002).

assistant: **Concept**

In the first conference in this series we brought together researchers on brain development with those from infant psychology to discuss the normal functional development of the brain. In this second conference in the series proposed here we will shift attention to the ways in which functional brain development can go wrong. Specially, we will shift attention to the ways in which functional brain development can go wrong. Specifically, we will bring together scientists with a clinical interest in abnormal development and the effects of early brain damage, with theoreticians interested in modelling the processes underlying functional brain development.By bringing these two groups together we hope to interest the theoreticians in modelling process of abnormal, as well as normal development, and to inform those studying developmental disorders about theoretical models that may help us to a deeper understanding of these problems. The following topics will be reviewed: relationships between cortical functional specialisation and regional heterochrony of maturation; interactions between subcortical and cortical development; evidence for pre-specified cortical specialisation; abnormal cortical specialisation and functional brain plasticity; development of frontal cortex functions and of interhemispheric co-ordination (cortical and subcortical pathways), models of cortical functioning.ftp://ftp.cordis.lu/pub/improving/docs/HPCF-1999-00097-1.pdf
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Entrenched: Elite Capture and Social Mobility'.

assistant: **Objectives**

New democracies often inherit entrenched political or economic elites who retain substantial influence over policymaking. This project studies a number of systematic and idiosyncratic shocks to such elites and examines whether these critical junctures affect the persistence and decline of their economic and political power. It is pertinent to economists and political scientists and contributes to ongoing debates regarding social mobility and elite capture.I propose to study these topics within the historical context of Prussia, where the landed nobility formed an entrenched elite wielding enormous power throughout the 19th century. In the 20th century, they faced substantial economic and political disruptions (disempowerment in a revolution, death in two world wars, and displacement from their estates), yet arguably remained highly influential.I will create a novel panel dataset, digitized from primary and secondary sources, documenting ownership and size of the universe of ca. 22,000 large landed estates from 1871 to 1945. This core dataset will be augmented with individual-level data on incumbents in various non-elected offices in the public administration and archival data on social ties among the elite. In combination, these data enable the analysis of the social mobility and political influence of the landed elite with unprecedented detail, using institutional and idiosyncratic shocks to the elite for causal inference.WP1 (disempowerment) studies the impact of democratic transitions, which entail a de facto decline in the political value of land ownership, on the social mobility and political power of the elite. WP 2 (death) studies how individual shocks—the death of a family member in military service—affect the social mobility and ability to shape the political p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Calcification by Marine Organisms'.

assistant: **Innovation**

CalMarO aims at the comprehensive training of twelve young researchers in the field of calcification by marine organisms based on a Network of thirteen research institutions and four SMEs. The Network participants are acknowledged experts with complementary research or commercial approaches in this field.  Calcification is a fundamental physiological process of marine organisms that is largely determined by the characteristics of seawater. Calcifying marine organisms differ in their adaptability to variations in environmental conditions, in particular temperature and seawater pH. If global CO2 emissions continue to rise at current trends seawater pH may decrease to levels that are probably lower than have been experienced for tens of millions of years and, critically, at a rate of change 100 times greater than at any time over this period, with dramatic effects on productivity and marine ecosystems. CalMarO comprises investigation of calcification processes and the sensitivities to changes in environmental conditions at all scales ranging from cellular, organism, population to ecosystem, and regional to global levels. Covering this important topic in a training Network will offer young researchers an integrated perspective on an emerging problem and position their own work within the framework of a concerted effort to better understand the risks and consequences associated with ocean change.  Three pillars support the training programme: personalised programmes, Network activities and dissemination. The principle of co-supervision by at least two senior scientists and SME placement on the basis of an individual mentoring plan represents the core piece of the training programme, with links to joint activities across the Network. These include annual meetings and theme or
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Credits-based, people-centric approach for the adoption of healthy life-styles and balanced Mediterranean diet in the frame of social participation and innovation for health promotion'.

assistant: **Concept**

The CREDITS4HEALTH project’s main goal is to develop a person centric approach based on the “credits for health” concept to reduce sedentary behavior and enhance the level of physical activity and healthy dietary styles in people living in Euro-Mediterranean Countries. The concept of credits is simple and effective: this means that each participant will earn credits from his local, regional or national Health Authority on the basis of his/her participation and involvement in the achievement of an healthy life-style, and his/her attitude to sponsor this philosophy in his community. The CREDITS4HEALTH vision is therefore to have people directly acting for their health and well being, operating on three fundamental levers to enhance the quality of their lives, through the reduction of sedentary behavior, the active participation to the social life and the adoption of an healthier diet. The CREDITS4HEALTH approach is virtuous and straightforward: 1)First, we will define personalised algorithms containing dietary and physical activity prescriptions, taking into account the medical, psychological, social, and economic background of each person; 2) Once screened by the local Credits4Health Committee, the participant receives an electronic card, which enables him to track his compliance to the regime through a dedicated web based platform; 3)With his electronic card, the participant also gets access to a full range of suppliers which offer him goods for fulfilling his health-related objectives;4)Suppliers must be certified by the local authority, according to a specified set of requirements and they must certify the products they intend to commercialise for this initiative;5)Participants gain credits as far as they comply with their daily, weekly and monthly goals; they are als