RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Innovative nanotech-based detection equipment in the area of homeland security', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Following the January and November 2015 terror attacks in Paris, the need of Governments for identification and securitychecking systems to provide safety and control to critical infrastructure and people have increased dramatically. It isexpected in next years that nations will invest billions of dollars in security systems to upgrade and improve the safety andsecurity of the country (European ETD market will be worth $4.2 billion with a CAGR of 14% during 2015-2020).NTA strategic intent is to develop, manufacture and sell sophisticated systems for the security, safety and defenseindustries.NTA has developed proprietary technologies used in explosives and narcotics trace detection (“ETD” and “NTD”,respectively) applications. These systems are used by private companies and government agencies to screen baggage,cargo, other objects and people for the detection of trace amounts of explosives and narcotics.More specifically, NTA aims at launching on the market a new generation of universal instruments for pressure and chemicalmeasurements providing at the same time huge system simplification and high effectiveness.NTA Value Proposition is to provide its customers with instruments for selective and sensitive detection of explosives thatare characterized by significant design simplification and high cost efficiency.The proposed feasibility study has the aim to evaluate the technological, economic and financial sustainability of the project.In particular, the specific objectives of the feasibility study are:- complete final layout and product design, prototype experimental set up and select key suppliers;- define the certification phases;- enhance all measures to protect company’s knowledge;- fine tune the executive dissemination and exploitation plan;- elaborate the executiv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Feeding ecology of clupeoids larvae in upwelling ecosystems'.

assistant: **Innovation**

Clupeoid fisheries in coastal upwelling areas account for more than 30 % of total world catch. In these highly productive systems, populations of clupeoids are the main trophic link between the plankton system and higher trophic levels. Population size of clupeoids in these areas has presented dramatic variability in the past, with important economic and social consequences. Pelagic fish recruitment variability has been shown to depend on survival of larval stages, and food availability has been proposed as a critical factor to the survival of early life stages.Objective of the FECLUP (Feeding Ecology of Clupeoids Larvae in Upwelling ecosystems) project lies in studying the feeding ecology of cupleoids:(1) to determine the potential impact of food limitation, taking into account different prey types and sizes and the increase in larval size during ontogenetic development;(2) to relate the impact of food availability on recruitment, to other factors such as adult reproductive strategy, food web dynamics and larval transport during larval development.The project will be focused on cupleoid fish in the Canary and Humboldt Currents upwelling systems. The methodological approach will be based on the coupling of laboratory or field experiments (analysis of gut contents, analysis of stable isotopes) and simulations of the recruitment process with an Individual Based Model coupled to a biogeochemical and a hydrodynamic model. The approach allows hierarchizing the principal processes relating food availability and larval behaviour under different scenarios, such as global change, or high fishing pressure. It has been set up during previous researches of the proposing research unit. The present project is proposed under a framework of an Ecosystem Approach to Fisheries.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Ruthenium Based Protein-Protein Interaction Inhibitor’s'.

assistant: **Concept**

In this research, the fellow (Jayapal Reddy Mallareddy) will synthesize novel cell permeable fluorescent ruthenium complexes and demonstrate their utility for perturbing biological processes. This fellowship will build on the fellows expertise in synthetic chemistry (particularly peptide synthesis) applied at the biological interface, together with Leeds’ expertise in the design and synthesis of cell permeable inhibitors of protein-protein interactions. The project will ultimately furnish cell permeable fluorescent small molecules designed to act as inhibitors of key protein-protein interactions involved in disease development and progression. Such inhibitors can be used as tool molecules to understand biological processes, as sensors for malfunctioning proteins and as the starting point for development of new molecular therapeutics thus impacting the competitiveness of the EU, and the quality of life of its citizens, by facilitating new strategies for diagnosing and treating disease.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Ageing Trajectories of Health: Longitudinal Opportunities and Synergies' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The objective of the ATHLOS Project is to achieve a better understanding of ageing by identifying patterns of healthy ageing pathways or trajectories, the determinants of those patterns, the critical points in time when changes in trajectories are produced, and to propose timely clinical and public health interventions to optimise healthy ageing. Moreover, a new definition of ‘old age’ based on many characteristics rather than just the classical chronological definition of age will be used for calculating projections in each specific population and guide policy recommendations. To do so, the Consortium will create a harmonised dataset with over 341,000 individuals collated from existing longitudinal studies of ageing and including information on physical and mental health, biomarkers, life style habits, social environment and participation, among others. A single metric of healthy ageing using Item Response Theory (IRT) methods with individual items from the surveys will be used. Diverse statistical methods will be employed to define the trajectories (Generalised Estimating Equations, Structural Equation Modelling, Growth Curve Mixture Modelling, the TRAJ method and classification algorithms). Age Period Cohort will be used in the analysis to understand age cohort effects. Specific interventions both at the clinical and population level will be designed based on project’s results and will be disseminated. Additionally, the impact of those interventions on healthy ageing will be assessed with the micro-simulation method. Stakeholders will participate in the definition of outcomes, the creation of interventions and dissemination of results. ATHLOS will make available to scientists and stakeholders its resources by providing access to the methodology of harmonisation and t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Metastasis-associated altered molecular patterns in the brain' (ALTER-brain).

assistant: **Innovation**

Organ colonization is the most inefficient step of metastasis. However, once a few cancer cells manage to re-initiate their growth in the brain, the initial naïve microenvironment, which was not favouring and even actively limiting the number of potential metastasis initiating cells, is slowly rewired into a different ecosystem with pro-metastatic properties. In this project (ALTER-brain), we will study the biology of microenvironment reprogramming to explore innovative ways of treating metastasis.Microenvironment reprogramming relies on altered molecular patterns that emerge in specific brain cell types simultaneously to the outgrowth of metastases. Dissecting the biology of these emerging patterns and their functional consequences could provide the basis to prevent metastasis but also to treat advances lesions. A key objective of ALTER-brain is the identification of newly established functional networks among previously non-connected components of the microenvironment that are critical to nurture tumour growth.This research proposal focuses on metastasis in the brain given its rising incidence, poor therapeutic options and short survival rates upon diagnosis. ALTER-brain will use novel (i.e. spontaneous metastasis) and clinically relevant (i.e. relapse after therapy) experimental mouse models of brain metastasis combined with genetically engineered mice in which we will target specific components of the microenvironment. In addition, we will apply novel lineage tracing technologies to understand the origin and emerging heterogeneity of the reprogrammed microenvironment. Given the clinical relevance of our research, human brain metastasis provided by our clinical network will be used to validate key findings. ALTER-brain will identify key principles underlying the unkn
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Enhance environmental awareness through social information technologies' under Seventh Framework.

assistant: **Concept**

There is now overwhelming evidence that the current organisation ofour economies and societies is seriously damaging biologicalecosystems and human living conditions in the very short term, withpotentially catastrophic effects in the long term. The enforcement ofnovel policies may be triggered by a grassroot approach, with a keycontribution from information and communication technologies (ICT).Nowadays low-cost sensing technologies allow the citizens to directlyassess the state of the environment; social networking tools alloweffective data and opinion collection and real-time informationspreading processes. In addition, theoretical and modeling toolsdeveloped by physicists, computer scientists and sociologists havereached the maturity to analyse, interpret and visualize complex datasets. The proposed project intends to integrate all crucial phases(environmental monitoring, awareness enhancement, behavioural change)in the management of the environment in a unified framework, bycreating a new technological platform combining sensing technologies,networking applications and data-processing tools; the Internet andthe existing mobile communication networks will provide theinfrastructure hosting such a platform, allowing its replication indifferent times and places. Case studies concerning different numbersof participants will test the scalability of the platform, aiming atinvolving as many citizens as possible leveraging on the low cost andhigh usability of the sensing devices. The integration ofparticipatory sensing with the monitoring of subjective opinions isnovel and crucial, as it exposes the mechanisms by which the localperception of an environmental issue, corroborated by quantitativedata, evolves into socially-shared opinions, eventually drivingbehavioural changes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Fusion diagnostics' under Fifth Framework.

assistant: **Concept**

The conference will focus on future diagnostic requirements for fusion energy research and will emphasise advanced diagnostics, new techniques and areas where further progress is required. A principle aim will be to bring together experts from the magnetic and inertial confinement programs to stimulate ideas and establish links between researchers in both fields. This will provide an additional multi-disciplinary character to the conference. Plasma diagnostics play a crucial role in the process of optimisation of plasma production, heating and confinement. In Magnetically Confined Fusion (MCF), the use of advanced diagnostics for plasma control is becoming more extensive and will be essential for the envisaged long pulse operation of next step fusion burning experiments. In Inertially Confined Fusion (ICF) significant diagnostic advancements haye been made in areas such as core mix diagnostics and ultrafast imaging of the imploded plasma. The most recent advancements and state of the art in both MCF and ICF diagnostics will be represented at the conference through a number of keynote and topical lectures. The core of the conference programme will address a few selected topics where i) a significant link between MCF and ICF can be established and/or ii) significant progress has been made or is expected. The topics for the main sessions are:1) Next steps in ICF and MCF experiments,2) Diagnostic requirements for future experiments in ICF and MCF,3) Neutron measurements,4) Optical and X-ray diagnostics. One or two sessions on contributed papers on miscellaneous topics are also planned to encourage a broad conference attendance, especially from young researchers. A book of proceedings (collecting all papers presented at the conference) will be published through a commercial
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Foresight study for the development of an European NeuroImage Repository'.

assistant: **Concept**

The ENIR project aims to carry out a foresight study to investigate the scientific needs in relation to the development of a large and shared European multidimensional repository of high resolution magnetic resonance (MR) images of normal brains and brains with different neurodegenerative disorders (Alzheimer's, amyotrophic lateral sclerosis, Parkinson's disease, etc.) completed by clinical, genetic and neuropsychological data.The huge variability of brain morphology affects the judgement of what constitutes normality or the comparison among different brain groups. In order to model and manage this variability, a wide amount of brain images and information on the sources of variability is needed. To reach meaningful numbers, such a repository cannot be collected in a single centre, but requires that brain images taken from many centres be pooled. A European repository of this kind does not exist at the present time due to the lack of a structured communication network among centres and of the huge heterogeneity of acquisition protocols and clinical information collected from the patients.The ENIR project will investigate the needed standardization topics and practical implications in acquisition, processing and storage of neuroimages by means of a co-ordinated approach to the setting up of a devoted research infrastructure, making the best use of those already existing. Consensus will be achieved on a number of currently discordant theoretical and practical issues that have so far hindered the setting up of a large European brain image repository. The proposed study will also identify standardized procedures in order to make the best use of existing repositories, in view of their increased integration towards the development of the future European infrastructure.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Inside the mind of a voter - Memory, Identity, and Electoral Psychology'.

assistant: **Innovation**

In many ways, social scientists still face an almost complete mystery when it comes to understanding what happens in a voter s mind while (s)he stands in the polling booth, form in hand, ready to accomplish his or her civic duty. What are the deep images, beliefs, and memories that may be activated when they finally have to make up their electoral mind? This project precisely targets this 'hidden part' of the voter's mind, particularly focusing on electoral memory, identity, and psychology and their impact on voters' behaviour in the context of both elections and referenda. The project uses a four-fold methodology with 2 series of interviews, experiments, and a survey component. It will shed unprecedented light on the entire notion of long term coherence of a voter s behaviour, regardless of whether they remain faithful to one political party or switch over time. In particular, our findings will help us to capture the logic of the vote of the 20-30% of the electorate who claim to be undecided hours before an election or a referendum and that of the up to 10% who claim to change their minds in the same period. The project will additionally enlighten us on electoral psychology in referendum voting, the elusive 'd term' (expressive value of the vote), the logic of participation, etc. The project comes with a pledge to publish a minimum of 4 books, 5 articles in major journals, several other articles and chapters, and, mostly, a genuine breakthrough in our understanding of electoral behaviour in a context of dealignment. It will also result in the creation of Europe's only Centre for Research in Electoral Psychology, which will become a focal point for political psychology and electoral research in Europe, and organise regular workshops, seminars, and a large conference.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Investigation into the Molecular Mechanisms Underlying NEmatode recognition by the Ma resistance protein in perennial plum roots' under Horizon 2020.

assistant: **Concept**

Plant-parasitic nematodes are major root pathogens that affect drastically plant development and growth. Predominant species, such as the root-knot nematodes (RKNs) Meloidogyne spp., represent a global threat for annual and perennial crops causing huge crop losses worldwide. In Europe, RKNs were mainly controlled by toxic pesticides that are getting banned. One of the most promising alternative to pesticides is to rely on biological control and on the plant innate immunity for disease resistance in crops. The plant immune system is a multi-layered network that enables the detection of pathogens using different classes of receptors. The presence/absence of such receptor can determine whether or not the plant will be resistant/susceptible to a particular disease. At INRA Sophia Agrobiotech Institute (ISA), an immune receptor gene Ma, from the toll/interleukin-1 receptor, nucleotide-binding and leucine-rich repeat (TIR-NB-LRR or TNL) family, has been cloned from the plum tree Prunus cerasifera where it provides a broad resistance against numerous RKN species. A unique feature of Ma resides in five repeated exons encoding a large C-terminal extention. Interestingly, each of those exons carries a recently characterized post-LRR (PL) domain which is found in a single copy in many other TNLs from different plant species. The PL domain’s function remains unknown but its conservation suggests an important role in TNLs. The peculiar architecture of Ma provides a great opportunity to decipher the involvement of the PL domain in TNL–mediated immunity. Combining complementary approaches, the proposed IMMUNE project aims to describe how Ma triggers immunity in response to RKNs in plant roots and how the PL domain participates in the recognition and signalling. This project, undertake