RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Transgenic and somatic gene therapy studies of the role of the vascular endothelial growth factor (VEGF gene family) in normal and pathological blood vessel formation' (1994-1998).

assistant: **Innovation**

OBJECTIVES* Molecular & genetic analysis of the role of the vascular endotheli al growth factor system in blood vessel formation during embryonic vascular deve lopment and pathological neovascularization.* Viral and non-viral gene transfe r of vascular endothelial growth factor to improve ischemic heart disease.Development of new blood vessels is essential for embryonic development and during pathological disorders such as ischemic heart and tissue disease, atherosclerosis, cancer, diabetes, wound healing and inflammation. A novel family of angiogenic growth factors, related to the vascular endothelial growth factor (VEGF) has been identified. These factors are unique and different from most other angiogenic factors by their secretion, potency and endothelial cell specific action. To date, their role in vivo during pathological vascular development is, however, largely elusive and indirectly deduced from gene expression studies. Despite its incompletely understood role in vivo, VEGF is currently being developed for (gene)therapy. Therefore, better insights in the in vivo role of VEGF and its family members is mandatory. This will allow more rational design of treatments for disorders resulting from either reduced blood vessel growth (tissue ischemia) by promoting neovascularization, or from excessive blood vessel growth (cancer, diabetic retinopathy) by preventing neovascularization.The objectives of this proposal are to generate transgenic animal models with over- or under-expression of wild type or mutant family members of VEGF, or with a genetically defined alteration in their expression pattern (tisse-specific inactivation and conditionally induced VEGF expression). Blood vessel formation, and the impact of its abnormalities as a consequence of the genetic manipulat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Rates of Mortality Improvement', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Project ROMI aims answer three questions in demography:1) What is the formal relationship between of mortality improvement, below replacement fertility and population and population growth?2) Are period cohort effects more important for the steep increase in life expectancy, lasting now for more than one century?3) Can we develop a better method to forecast mortality and life expectancy since standard approaches are typically not able to model the age-shift in mortality improvements over time?Project Romi approaches these questions from an innovative perspective: the analysis of rates of mortality improvement. A by-product of this research will be the development of new methods such as smoothed surface maps over age and time of the pace of mortality improvements and an alternative procedure to forecast mortality.The importance of project Romi is that providing answers to any of the questions will have permanent impact not only for demographers but also for scientists in other disciplines as well as for public-policy makers.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Globalisation and the Education of Adults'.

assistant: **Innovation**

The proposal’s objective is to identify and examine how globalisation processes are redefining the nature and scope of adult education in response to global challenges by asking the following research questions:1. How do political entities, interest groups and other actors influence the transnational policy development process and how, in turn, do they respond to transnational policies in adult education?2.How does international cooperation affect state policies concerning adult education, planned and implemented, in three socio-economic and political systems that are representative of the North-South division?GLOBE-A challenges traditional categorisations applied to studying adult education in Western societies or in transition and less developed countries and attempts to reconceptualise existing relations between adult education, policy analysis, and political and social science.The study adopts a mixed-method design, were new empirical data will be of qualitative nature, while existing quantitative data will play a supportive role, and it follows a comparative approach that combines a vertical and a horizontal perspectives. The vertical perspective explores how the global and the local mutually shape each other by looking at the flow of policies between transnational entities, regional organizations and local governments. The horizontal perspective examines interactions and disjunctions across sites in Europe, Northern and Latin America by exploring how changes in transnational, regional and local policies influence educational practices in multiple sites.GLOBE-A is expected to generate knowledge specific to a sample of world regions, while developing a new perspective. This perspective could be applied to study adult education in contrasting socio-economic, cultural
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'WeCount: Citizens Observing UrbaN Transport' (WeCount), addressing dissemination and exploitation.

assistant: **Impact**

WeCount aims to empower citizens to take a leading role in the production of data, evidence and knowledge around mobility in their own neighborhoods, and at street level. The project will follow participatory citizen science methods to co-create and use innovative low cost, automated, road traffic counting sensors (i.e. Telraam) and multi-stakeholder engagement mechanisms in 5 pilots in Madrid, Ljubljana, Dublin, Cardiff and Leuven. Following this approach, we will be able to quantify local road transport (cars, Heavy Goods Vehicles, active travel modes and speed), produce scientific knowledge in the field of mobility and environmental pollution, and co-design informed solutions to tackle a variety of road transport challenges. Moreover, the project will provide cost-effective data for local authorities, at a far greater temporal and spatial scale than what would be possible in classic traffic counting campaigns, thereby opening up new opportunities for transportation policy making and research. In WeCount, we empower citizens to develop evidence-led interventions into the political discourse on civic and environmental issues. By putting citizens at the heart of the innovation process, the project seeks to overcome existing technological and societal silos so that citizens can champion a new perspective on road transport that take into account their own concerns in pursuit of better quality of life and more equitable, healthy futures.


**Keywords:** data production,  traffic counting,  transport impacts
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Construction of realistic initial data coalescing binary black holes in circular orbits'.

assistant: **Innovation**

The beginning of the activities of ground-based interferometric gravitational observatories for detecting gravitational waves, urgently demands the existence of realistic and detailed theoretical predictions for the expected gravitational radiation.This proves to be essential both for the analysis of the received signals (physical information plus noise) and for their interpretation. Black hole coalescence is the astrophysical source which stands as the most promising candidate for early detection. The detailed theoretical description of this phenomenon and its corresponding gravitational waves demand the use of numerical techniques.The first step in such a numerical study is the determination of the so-called initial data. In the context of quasi-circular inspiraling binary black holes, the match of these numerical techniques with recently developed analytical methods can be crucial in order to identify the relevant initial data. This defines the fundamental objective of this project: constructing a set of astrophysically realistic initial data for highly detailed numerical evolutions.In order to achieve this goal, the work is structured in two parts:- setting of a well-posed system of elliptic partial differential equations which constrain the physical data; and- numerically solving this system of equations by applying spectral methods in which the Meudon group represents a world-leading team.The two parts will be carried out consecutively and will demand the use of very different strategies. For the first one, the employed methods will be basically analytical, while the second one will consist in the construction of a C++ code. The Meudon group represents a perfect environment to develop both stages.The final outcome of the project will provide the necessary input fo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'COmmunity heavy-PAyload Long endurance Instrumented Aircraft for Tropospheric Research in Environmental and Geo-Sciences'.

assistant: **Objectives**

COPAL has the objective of providing the European scientific community with an unique research aircraft platform, capable of reaching and operating in any remote area in the world and offering a heavy-payload for integration of a large panoply of instruments for research in environmental and Geo-sciences. It will offer an unprecedented opportunity to countries that are not yet operating research aircraft to develop expertise in airborne measurements and participate to international multidisciplinary experiments. The Consortium includes a SME and 10 national research funding institutions, among which 6 are research councils, 3 are meteorological services supporting research, and one is a national aerospace research institution. 7 participants are members of the EUFAR network of European aircraft operators for research in Geo-sciences. User requirements will be refined and translated into specifications for aircraft performance and modifications for research. The acquisition, modification, maintenance and operation costs will be precisely quoted. Procedures will be defined for the selection of the aircraft and data management operators. A network of academic centres of excellence and SMEs will be constituted for the development and airborne certification of innovative instruments for the community aircraft. New governance schemes will be elaborated for evaluation of access proposals and allocation of time slots, which reconcile the Pan-European use of the aircraft, with national authority in term of scientific programming. These activities will be coordinated with EUFAR, with the operator of community research aircraft in the USA, and with the other Preparatory Phase studies, especially those with points of similarity with COPAL, such as the research vessels. They will su
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'A Real-time imaging and classification system for low-grade glioma detection during brain surgery' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Brain tumors remain one of the most incurable illnesses we know; patients have poor prognosis and less than a decade of life expectancy. The oncologist’s toolkit is rather limited as chemotherapy agents have limited access to the brain due to the blood brain barrier selective permeability and radiotherapy results in extensive damage to tissue well beyond the targeted area; leaving surgical removal of the tumor as the most effective approach. It has now become clear that the completeness of the surgical removal of the tumor is the most important factor determining recurrency of the illness. As such, tools that enable neurosurgeons to effectively remove the tumor are of fundamental importance in the surgical theater. Recent advances in intraoperative fluorescent labeling of common brain tumors has proven to dramatically improve surgical outcome. Unfortunately, no such labeling or intraoperative aid exists for the highly infiltrative low-grade glioma (LGG), making it the deadliest type. This PoC project aims to tackle this urgent unmet need and develop an intraoperative, real-time imaging and tissue classification tool for precise on-site identification of LGG tissue. The core technology emanates from the multiphoton ultrafast volumetric imaging we developed (now able to run in real-time) to study the link between neuronal activity and blood flow. Here we harness this unique technology and extended it to perform real-time label-free multimodal acquisition and image processing using the latest deep-learning tools. Our tool will provide surgeons with the ability to discern, while operating, healthy vs tumor tissue. Together with neurosurgeons, a technological hardware partner and an expert in artificial intelligence, we are positioned to generate the first-of-its kind protot
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Towards Unification of Algorithmic Tools' in the context of a Horizon 2020 call.

assistant: **Objectives**

Over last 50 years, extensive algorithmic research gave rise to a plethora of fundamental results. These results equipped us with increasingly better solutions to a number of core problems. However, many of these solutions are incomparable. The main reason for that is the fact that many cutting-edge algorithmic results are very specialized in their applicability. Often, they are limited to particular parameter range or require different assumptions. A natural question arises: is it possible to get “one to rule them all” algorithm for some core problems such as matchings and maximum flow? In other words, can we unify our algorithms? That is, can we develop an algorithmic framework that enables us to combine a number of existing, only “conditionally” optimal, algorithms into a single all-around optimal solution? Such results would unify the landscape of algorithmic theory but would also greatly enhance the impact of these cutting-edge developments on the real world. After all, algorithms and data structures are the basic building blocks of every computer program. However, currently using cutting-edge algorithms in an optimal way requires extensive expertise and thorough understanding of both the underlying implementation and the characteristics of the input data. Hence, the need for such unified solutions seems to be critical from both theoretical and practical perspective. However, obtaining such algorithmic unification poses serious theoretical challenges. We believe that some of the recent advances in algorithms provide us with an opportunity to make serious progress towards solving these challenges in the context of several fundamental algorithmic problems. This project should be seen as the start of such a systematic study of unification of algorithmic tools with the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Mathematical Methods for Robust Financial Risk Management'.

assistant: **Objectives**

Reliable techniques in finance should take into account the unavoidable modelling error. This is the main focus of this project that we intend to address from two viewpoints raising new questions in applied mathematics.Our first research direction is to device robust risk management methods which use the market observations and the no-arbitrage principle. A classical result in financial mathematics essentially states that, in idealized frictionless financial markets, the price processes of tradable securities must be a martingale under some equivalent probability measure. We propose to adopt a conservative viewpoint by deriving the bounds over all possible choices of martingales. By accounting for the rich information corresponding to the prices of European call options, we arrive naturally to a new optimal transportation problem. We intend to analyze several questions: clarify the connection with the Skorohod embedding problem, understand better the duality, develop the corresponding numerical techniques, explore the robust portfolio optimization problems under such constraints, and understand their impact on the risk measurement.The second direction of research proposed in this project concerns the recent theory of Mean Field Games, recently introduced by Lasry and Lions. Our intention is to address this theory from the probabilistic point of view. The main observation is that the MFG equations, consisting of a coupled system of a Fokker-Planck equation and a semilinear Hamilton-Jacobi-Bellman equation, can be viewed as an extension of the theory of forward-backward stochastic differential equations (FBSDE) with mean-field dependence. This theory provides a simple modelling of the interactions which may be used to explain important phenomena on financial markets as th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Friends with benefits – the role of endophytic bacteria in legume nodules containing nitrogen-fixing rhizobia' (FITTER).

assistant: **Innovation**

From shoot to root plants are exposed to a diverse range of microorganisms, which can play a major role in plant health, growth and development. A small fraction of bacteria can cause disease, the vast majority of bacteria has no known effect on the host, but there are bacteria that are beneficial to the plant. These microbes are able to protect plants from pathogens, modulate immune responses or assist in nutrient uptake. The best studied beneficial relationship for both plant and bacteria, is the long-term biological interaction (symbiosis) between legumes and nitrogen-fixing bacteria. These bacteria called rhizobia, are hosted in root nodules of legumes such as clover or alfalfa, where they fix atmospheric nitrogen. However, rhizobia are not the sole occupants of nodules and despite early findings of the presence of other nodule associated bacteria (NAB), the diversity and role of NAB in symbiosis and plant growth has remained neglected.  Legumes are important crop in agriculture worldwide and as such, the potential of plant growth promoting bacteria and increase of nitrogen-fixation abilities is a major topic of research aiming to enhance agricultural productivity. Investigating the genetic material of all the microbes, the so-called microbiome, of legume root nodules, will allow investigation of genetic features of those bacteria, which contribute to increased plant growth and nutrient availability. Here, I will use a holistic sequencing approach to (i) unravel the diversity and metabolic properties of NAB in legume nodules and (ii) gain insights into the environmental factors affecting NAB community composition, (iii) determine to what extent the bacterial community in the soil (rhizosphere) drives nodule community composition. The proposed research will provide a