RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'High brightness and novel waveguide laser diodes for information technology' (TRUE-BLUE).

assistant: **Innovation**

The objective of this project is to develop novel bright light sources for various information technology applications such as optical storage, optical displays, optical amplification and materials processing. High brightness is a key issue for light source suitability in many of these applications - particularly in storage and display - since brightness (or luminance) dictates the optical power density that can be obtained at a focused spot. These sources will utilise a novel type of waveguide to develop, using GaAs technology, a new class of compact waveguide engineered, high power and brightness, short wavelength laser diode -based light source. These enhanced brightness light emitters will benefit applications of high power laser diode technology currently limited by the poor brightness, substantial astigmatism and slow switching speed of existing devices. Such applications include; high brightness, short wavelength light generation for rewriteable optical storage technologies and lithography, and high speed switching and beam-steering for free space optical interconnects.We have discovered a new class of waveguide structure that can enhance the performance of semiconductor lasers and other optical components and sensors. A particularly interesting feature of this waveguide geometry is that energy is extracted from a large area while a well defined small beam profile is maintained. This effect should dramatically increase the optical power that can be extracted from a laser diode at a given power density while ensuring that brightness is not lost. In the first year phase of this project, our approach will concentrate on experimentally demonstrating optical waveguides in GaAs heterostructures which exhibit such guided mode configurations. Fabrication of planar wavegu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Polysaccharide-based membrane for sublingual vaccination' (PolyVac) targeting Horizon 2020.

assistant: **Abstract**

Vaccination has been acknowledged as one of the most effective methods against life-threatening diseases. Vaccines administered by the mucosal route (oral, vaginal…) present the advantage to be needle-free and reduce the risk of pathogen transmission. Among the existing mucosal vaccines, the sublingual ones are an interesting way of immunization since the sublingual mucosa is particularly thin and would allow easy penetration of antigens. Also, this administration allows to bypass the gastrointestinal tract, has better safety record than intranasal vaccines and have better compliance for vaccinating infants and children. Additionally, they have a fast removal by body fluids and enzymes. PolyVac introduces a pioneering system for controlled targeted delivery of bioactive molecules and, for the proof of concept envisages the development of a sublingual vaccine for HIV. This concept comprises the development of a free-standing (FS) multilayer membrane that will present the double specificity to be immunoactive and specifically target the immune cells. To achieve this end, the FS will be loaded with a model antigen for immunotherapy and a chemotactic cytokine to specifically target the antigen presenting cells. Once loaded with the proteins, the FS membrane will become a bioactive patch. This patch will permit to deliver subunit vaccine components both spatially and temporally as dendritic cells will be attracted at the sublingual mucosa/patch interface ensuring efficient immune responses. Preclinical studies will follow in mice, by monitoring their immune response, for clinical translation and commercialisation of the proposed technology. It is expected to have, as final product, an innovative sublingual patch for human immunotherapy that among the advantages presented abo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'C2 Advanced Multi-domain Environment and Live Observation Technologies' (CAMELOT), addressing dissemination and exploitation.

assistant: **Impact**

The creation of the Schengen area has been one of the major achievements of the EU. However, this agreement requires countries to cooperate tightly in order to keep a high level of security at their internal borders, as well as to share the responsibility of managing external borders. Such a variety of borders (land, sea and air) and current challenges requires a consistent approach to border surveillance, based on a plethora of heterogeneous assets. These can be manned or unmanned, ranging from sensors (optical, radar, IR) to unmanned platforms (UAV, UGV, USV or UUV), and need to be combined to offer an integrated situational picture of the area under surveillance and of their location. In order to effectively control their operation and manage the large amounts of data collected by them, new approaches for command and control need to be considered, allowing efficient interaction between the operator and the different assets in the field. CAMELOT proposes to develop and demonstrate different advanced command and control service modules for multiple platform domains, based on a SOA architecture that specifies internal and external interfaces, allowing the development of a modular and scalable command and control station, customisable to the user needs. This architecture can be based on results of previous studies and work or open architectures that may prove more suitable and the interfaces can take advantage of the standardisation work that has been done already. After the definition, CAMELOT partners will prototype service modules according to their expertise, background individual technologies and practitioner needs. These will be integrated progressively in specific testing along the project. This prototype development approach will culminate in 2 final demonstratio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Determination of the sensing and transcription mechanisms of bacterial metal sensors using pulsed EPR' to be submitted under Seventh Framework.

assistant: **Abstract**

In this proposal, Dr. Ruthstein and her new group at the chemistry department in Bar-Ilan University, Israel, will determine the sensing and transcription mechanisms of metal ion sensors in bacteria. Metals are commonly found as natural constituents of proteins; however, many metal ions can be toxic when free in biological fluids. Hence, microorganisms have evolved considerable regulatory machinery to control the intracellular and extracellular concentrations and types of metal ions encountered in their microenvironments. Gene regulatory proteins, called metal sensor proteins mediate this metal traffic control. These proteins have evolved metal coordination sites that “sense” specific metal ion and activate or inhibit DNA binding or transcription activation, thereby controlling the expression of genes that mediate what must be an exquisitely selective adaptive response. In order to understand how the sensor senses a specific metal and by this initiates a biological process, one has to be able to probe strutuctural changes that occur in the protein as a function of binding of the correct and wrong metal ion, and the binding of the DNA. This work will use site-directed spin labeling together with pulsed electron paramagnetic resonance spectroscopy (EPR) to shed light on such processes. EPR is an excellent tool to resolve systems that evolve protein-protein interaction and protein-DNA interaction. Distances up to 80 Å between two paramagnetic spin labels can be measured by pulsed EPR. In some cases, the measurement of one distance (or a few) is sufficient to establish the plausibility of a mechanism or corroborate a proposed structure. This work will initially focus on two Cu+ sensors (CsoR, CueR) from CsoR and MerR families. The first family inhibits DNA binding upon meta
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for '‘GET READY, WORKERS OF SPAIN!’ : THE RUSSIAN REVOLUTION AND ITS INFLUENCE ON THE NATURE OF POST-WORLD WAR I SOCIAL CONFLICT IN SPAIN' in the context of a Seventh Framework call.

assistant: **Objectives**

For this project, Dr. James Matthews will research the effects of the Russian Revolution of 1917 and its aftermath – the Russian Civil War – in the causation and course of post-World War I (WWI) political and revolutionary upheavals in Spain between 1917 and 1923, one of the most bitter social conflicts in post-war Europe. He will analyze the history of transmission of information and ideas with the aim of understanding the links between reported events from Russia and the militancy of Spanish organized labour and peasantry, which was particularly concentrated in Catalonia and Andalusia.Post-WWI social conflict helped shape the course of twentieth-century Spanish history, and its legacies include the Primo dictatorship and violent social warfare in the Spanish Civil War. While the period has attracted significant academic interest, it has lost ground in Spanish historiography over the last 30 years. Nevertheless, crucial questions, such as the international influence on the course and nature of the social conflict, are not yet well understood.The objective of the proposed research is to determine the role of transmission of information from Russia to Spain during this period. Matthews will analyze references to the Russian Revolution in the Spanish press, as well as the image of revolutionary Russia constructed by political and union representatives, political delegates and other transmitters, such as film screenings. He will study militants as well as references to Russia from government and counter-revolutionary groups. The results from this objective will shed new light on the image of revolutionary Russia from Spanish perspective. The project will also significantly expand on the current historiographical interest in studying social movements from the perspective of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Support Action Towards Evaluation, Learning, Local Innovation, Transfer and Excellence' to be submitted under Horizon 2020.

assistant: **Abstract**

SATELLITE will function as anchor for the entire CIVITAS Network, coordinating and supporting ongoing and future CIVITAS2020 projects. SATELLITE will address the MG5.5b call topic by helping cities gain better access to innovative solutions to properly address transport challenges they are facing. SATELLITE will make sure the latest innovations resulting from European urban mobility research reach cities through adequate cross-project coordination and exchange mechanisms. For innovations to be properly scaled up, sufficient information on their actual impact is required. SATELLITE will further elaborate the CIVITAS Impact and Process Evaluation Framework and provide IA projects with support mechanisms to implement and apply this framework. Through capacity-building, SATELLITE will provide city practitioners with the necessary skills to apply innovations in their own context, while additional exchange activities will prepare for the actual transfer and take-up of these solutions through community building approaches where cities can learn from their peers. Moreover, the project enhances the direct exchange and cooperation between the public and private sector, offering a dedicated online marketplace for urban transport innovations. SATELLITE dissemination activities will promote CIVITAS successes and improve access to available solutions through a varied range of communication tools and activities. Structured networking among all CIVITAS Forum members, with the annual conference as main highlight and with strong links to CIVINETs will encourage lasting capitalisation of activities. Unique selling points include: functioning as bridge between past and future of CIVITAS; bringing research tools to a marketplace for improved application and accessibility; gathering leading
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Adaptation to the new environment of the Science Academy Institutes in Russia analysis of the socialist and post-socialist of the Science Academy Institutes in Russia and their mode of adaptation : the case of Akademgorodok' (1994-1998).

assistant: **Concept**

Foreseen ResultsThe proposed working scheme is based upon an effective distribution of tasks, roles and responsibilities between the Russian research units and the European task force. The two Russian institutes will in fact be fully responsible for preparing, organising and carrying out the case studies and research work concerning local authorities and environment. The European teams, on the other hand, will prepare the theoretical basis and framework to bring forward the economic analysis of the institutes and the linked industrial apparatus.The principle of common work on theoretical concepts in which all proposers take part, and on the realisation of case studies in smaller working units, bringing together two or three proposers for each one of the case studies will guarantee homogeneity of the joint research work and full scientific cooperation and exchange between the four organisations.Finally, the publishing and proliferation of the results will be responsibility of the consortium as a whole. Moreover, Novosibirsk State University is intentioned make the case studies topics of its courses in applied and industrial economics.The 1992 economic reforms implied a complete rupture with the past and forced a drastic reorganisation of research in Russia. For units involved in research this rupture means the necessity to take independent internal decisions, replace the old and no more functioning supply channels, find new means to access to capital (equity or debt), ... Previous research work as an activity with a monetary economic value, is the process that many research units and institutes are following to adapt to the new competitive environment. In post-Socialism the Academy institutes are administratively and hierarchically under the Science Academy and can not b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Neuro-Plasmonics' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Research neuronal signaling is the subject of a very large community, but progresses face a dense multi-scale dynamics involving signaling at the molecular, cellular and large neuronal network levels. Whereas the brain capabilities are most likely emerging from large neuronal networks, available electrophysiological methods limit our access to single cells and typically provides only a fragmented observation, on limited spatial/temporal scales. Therefore, broadening the spectrum of scales for observing neuronal signaling within large neuronal networks is a major challenge that can revolutionize our capability of studying the brain and its physio-pathological functions, as well as of deriving bio-inspired concepts to implement artificial system based on neuronal circuits. We propose the development of an innovative electro-plasmonic multifunctional platform that by combining different methodologies emerging from distant fields of Science and Technology will provide a radically new path for real time neurointerfacing at different scale levels:1. The molecular scale: 3D plasmonic nanoantennas will give access to information at molecular level by means of enhanced spectroscopies with particular regard of time resolved Raman scattering.2. The single-neuron scale within neuronal networks: by both in-cell and extra-cell couplings with 3D nanostructures which work at the same time as plasmonic antennas and CMOS 3D nanoelectrodes.3. The scale of large neuronal networks: by CMOS high-density electrode arrays for spatially and temporally resolving neuronal signaling form thousands of measuring sites.This is achieved by exploiting an innovative nanofabrication method able to realize 3D nanostructures which can work at the same time as plasmonic nanoantennas and as nanoelectrodes. T
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Localization and interactions of DNA damage response and cell cycle checkpoint proteins in yeast and chicken cells using fluorescente microscopy'.

assistant: **Concept**

Cancer is a major killer in the western world, second only to heart disease as a cause of mortality. Despite its impact cancer is a poorly understood disease. Fundamental research into both the causes and mechanisms of cancer are required if the outlook for cancer patients is to be improved. Cancer is caused by an accumulation of mutations, a process referred to as tumour progression.This accumulation is required since there are multiple control mechanisms to prevent cells becoming cancerous. Many cancers involve mutations in the DNA repair machinery allowing further mutations, leading to tumour progression and cancer. It is likely that mutations in DNA repair and cell cycle checkpoint are early steps in tumour progression. Significantly, mutations of some proteins in this study cause genetic diseases predisposing humans to cancer.The aim of this project is to study the localisation and interactions of DNA damage repair and cell cycle checkpoint proteins after induction of DNA damage. This will be achieved by tagging selected proteins with fluorescent protein motifs and studying them using fluorescence microscopy. The large amount of conservation in the relevant cellular mechanisms allows the use of model organisms such as yeast and DT40 chicken cells.I will initially exploit the ease of genetic manipulation in the yeast Saccharomyces cerevisiae to replace genomic copies of the proteins of interest with fully functional fusion constructs of the relevant protein with either Yellow or Cyan Fluore scent Protein (YFP or CFP). Initial studies will focus on localisation of single proteins after DNA damage, followed by Co-localisation of protein pairs. Interesting interactions detected in yeast experiments will be further studied in chicken DT40 cells.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Architectures for fLexible Photonic Home and Access networks' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The ALPHA project addresses the challenges of building the future access and all types of in-building networks for home and office environments. The proposal supports the evolution towards a cognitive network by dynamically utilising the resources of an optical network infrastructure to support a heterogeneous environment of wired and wireless technologies.The project investigates innovative architectural and transmission solutions based on the manifold of optical fibres (single-, multi-mode and plastic) as well as wireless technology to support both wired and wireless services in a converged network infrastructure. The focus is on using the newest physical layer achievements and adequate management and control algorithms to reach a yet unprecedented end-to-end provisioned capacity for access and in-building networks at a fraction of the price of today's technologies and to simultaneously include the transport of existing 2G/3G and Beyond 3G (B3G) signals whether they are Internet Protocol (IP) or non-IP-based.<br/>The project starts with analysing the potential future bandwidth and quality-of-service (QoS) requirements which can be posed by future services in the scope of access and in-building networks such as Ultra HD Video, Local Storage Area Network, remote medical applications and others, and mapping those requirements into network specifications. The questions on the best applicable media, necessity for optical layer dynamics, compatibility of network types at the physical layer, foundations for better QoS provisioning and embedding of 2G/3G and B3G signals into the networks are then addressed within the project.<br/>The project pursues experimental validations of close-to-maturity technologies in laboratory tests and field trials by intensively exploiting the th