RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Saving Cardiac Arrest Patients with Hypothermic Lung Conservative Liquid Ventilation' (Luncolive).

assistant: **Innovation**

Orixha offers a major clinical breakthrough in Critical Care with its unique LUNg COnservative LIquid VEntilation (hence LuncoLive) technology. It powers the Vent2Cool medical device to induce ultra-rapid protective cooling of heart and brain of resuscitated cardiac arrest patients.  Vent2Cool will increase their survival rate by tackling the reperfusion injury of Post Cardiac Arrest Syndrome .LuncoLive project will enable clinical validation of Vent2Cool as a new gold standard for post-resuscitation care. Orixha will industrialize and miniaturize the technology to increase usability as well as reduce costs and environmental impact, in particular through recycling of the Liquid2Breathe breathable liquid. Its success will enable Orixha to market the first Vent2Cool devices in the EU by 2028 and reach profitability by 2030. It will also strengthen Orixha's ability to develop future applications for respiratory support and pre-hospital emergency care.


**Keywords:** Medico-economics,Clinical trial,Recycling consumables,Intensive care,Breathable liquid,Respiratory support,Respiratory distress,Temperature management,Therapeutic hypothermia,Quality of life,Ventilators,Resuscitation,Cardiac arrest,Liquid ventilation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Evolution of Physiology: The link between Earth and Life' in the context of a Horizon 2020 call.

assistant: **Objectives**

The history of life is a subject that attracts the interest from both researchers and the society in general - it is in the human nature to wonder about our own history. Our only sources of information about microbial evolution reside in genomic data and geological records. Major advances in sequencing techniques are overwhelming databases with rich and novel insights into microbial taxonomic diversity, in particular about new uncultured lineages. Through metagenomics we now know that they are there but we still do not understand what they are doing.The key to that understanding is not genomics, it is physiology.Our main impediment to understand environmental microbial life is our lack of insights into the physiology of newly discovered lineages, how they harness and conserve energy.While phylogenetic trees based on universal genes can be generated for thousands of lineages at a time, they do not represent the genome as a whole and, most importantly, due to lateral gene transfer, branching patterns in the tree of life have never correlated well with key physiological traits.The goal of this proposal, whose focus is physiology, is to better understand how microbes harness energy from available environmental sources, how they learned to use new ones, and how this process unfolded during microbial evolution.This will involve i) large-scale comparative phylogenetic analysis of genes involved in and genomically associated with physiology combined with ii) experimental data, using as evolutionary constraints geochemical records of available environmental energy sources.With a top-down approach this work will successively eliminate among extant biological traits ones that cannot be ancient, constraining the physiological space of older microbial solutions.This proposal will le
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'An Integrated Network on Climate Change REsearch Activities on Shrubland Ecosystems' (INCREASE) targeting Seventh Framework.

assistant: **Abstract**

The network INCREASE consists of 6 infrastructures (large-scale field sites) with experimental manipulation of climate e.g night time warming and extended summer drought. Within INCREASE we will improve the technology and methodology for studies of climate change effects on European shrublands. The main objectives of INCREASE are: 1. To optimize technologies and methodologies for non-intrusive field manipulation of climate change in shrubland ecosystems by development, testing and application of new technology and methods i) to optimize the field manipulations of warming to 3-4 °C (in agreement with the newest predictions of global warming by the IPCC (2007)), ii) to develop, test and apply the combination of warming and drought and the combination with CO2. 2. To improve and develop non-destructive techniques and methods for measurements of physical, chemical and biological effects of climate. 3. To stimulate collaboration within the scientific community around climate manipulation experiments i) within the infrastructure by means of e.g. common research, common protocols, test of equipment, data syntheses, ii) between the infrastructure and related infrastructures beyond the proposal, and iii) scientists within relevant fields 4. To provide access to a unique set of large scale climate change experiment for European scientists. 5. To develop and provide access to a comprehensive data base of experimental data. 6. To develop and provide access to a dynamic ecosystem model for scrubland ecosystems 7. To test and apply non-destructive methods for ecosystem carbon assessment and important underlying processes of root dynamics and carbon transformations in the soil.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'End-to-end Reconfigurability E¿R' (E2R) targeting Sixth Framework.

assistant: **Abstract**

The End-to-End Reconfigurability (E2R) project aims at bringing full benefits of the valuable diversity within the Radio Eco-Space, composed of wide range of systems such as Cellular, Wireless Local Area and Broadcast. The key objective of the E2R project is to devise, develop and trial architectural design of reconfigurable devices and supporting system functions to offer an expanded set of operational choices to the users, applications and service providers, operators, regulators in the context of heterogeneous mobile radio systems.Innovative Research, development and proof of concept will be sought in end-to-end aspect, stretching from user device all the way up to Internet protocol, and services, and in reconfigurability support, intrinsic functionalities such as management and control, download support, spectrum, regulatory framework and business models. End-to-End reconfigurability systems will provide common platforms and associated execution environment for multiple air interfaces, protocols and applications, which would yield to scalable and reconfigurable infrastructure that optimise resource usage, increased network and equipment capability and versatility by software modifications.The users will be benefiting from these capabilities by reaching required service at times and places when and where needed at affordable cost. Furthermore, E2R proposes also to serve niche markets and provide users with special peculiar services via customised solutions that are open, flexible and programmable at all layers. E2R will thus contribute to the realisation of the Ambient Space through which a modern society interacts and communicates with key capabilities of the Radio Eco-System and finally actively influence European industrial and economic competitiveness. Standardis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Quantitative Genetics of Caste in Social Insects' in the context of a Seventh Framework call.

assistant: **Objectives**

The social insects are established model systems for the study of social evolution and are emerging model systems for studying the evolution of behaviour, aging, and complex social phenotypes. However, we know very little of the genetic basis of social insect phenotypes. This is a major limitation because the genetic architecture underlying traits determines how traits respond to selection. The purpose of the proposed research is to develop and implement novel approaches to study the evolution of social insect phenotypes. The two main research objectives are to compare the genetic architecture of two fungus growing ant species that differ in social complexity and to use artificial selection to study how different components of pharaoh ant phenotypes independently respond to selection. While Europe has emerged as a centre of social insect research, it has lagged behind the United States in the field of quantitative genetics, the study of the genetic basis of phenotypes. The researcher (Dr. Linksvayer) has been trained in quantitative genetics at leading institutions in the United States and has pioneered the application of quantitative genetic approaches to social insect systems. The host institution, the Centre for Social Evolution at the University of Copenhagen, is a leading European institution for the study of social insect evolution and has unique facilities, personnel, and experience with the two proposed study systems; the host (Prof. Boomsma) is one of the leading scholars in the field. The proposed research is an ideal match of the unique attributes of the host institution and researcher, and thus provides a perfect opportunity for the transfer of knowledge between Europe and the United States. The study of the genetic and molecular bases of traits is rapidly e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Establishing services enhancing the innovation management capacity of the Slovak SMEs in the Enterprise Europe Network in 2017-2018' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Main objective of the action is improving the innovation management capacity of two SME target groups: (1) Beneficiaries ofthe SME Instrument by provision of the specialised Key Account Management services, and (2) SMEs with significantinnovation activities and a high potential for internationalisation through the targeted Enhancing the innovation managementservices. The proposed action will implement 54 seven-day service packages during the pilot action in 2017-2018.


**Keywords:** KAM, EIMC, innovation management, Enterprise Europe Network, SME Instrument
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Multi-level Embedded Closed-Loop Control System for Fluidic Active Flow Control Actuation Applied in High-Lift and High-Speed Aircraft Operations' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

ESTERA project objective is to develop and deliver prototype of Closed-Loop Control System optimized for Active Flow Control actuation applied at the wing’s trailing edge or wing’s body and used for drag reduction / buffeting control in high-lift and high-speed aircraft operations. The project objective shall be achieved by: acquiring requirements imposed on CLC-System (particularly in terms of working conditions, wing geometry and sensors / actuators location), numerical simulations of air flow speed and pressure at wing surface (without and with working actuators) to define regulation goals (pressure values that shall be achieved) and to select the best control strategy, building system-under-control mathematical model, selection of control techniques to be tested (PID, LQR, adaptive, hybrid, others), definition of test cases and scope of tests, construction CLC-System Mock-up from already available parts, testing of selected control techniques on wing model in wind tunnel provided by Consortium and their iterative improvement / efficiency optimization due to test results with support of MATLAB tool (applying stochastic and evolutionary algorithms) and finally production and delivery of CLC-System prototype to SFWA. Multi–level distributed CLC-System is proposed, constructed of signal conditioning units embedded in sensors, sub-controllers embedded in actuators and main controller, connected in digital communication network (e.g. ARINC 429). This construction shall improve CLC-System efficiency by separation of tasks performed at high and low level as well as improve CLC-System reliability by independency of local sub-controllers. CLC-System Prototype shall be miniaturized using FPGA/CPLD technologies to be embedded in AFC actuators and sensors. CLC-System prototype s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Optical mammography: imaging and characterisation of breast lesions by pulsed near-infrared laser light'.

assistant: **Objectives**

Breast cancer is the most frequent cause of death of women under 50 years and x-ray mammography suffers from a large number of false positive results. Near-infrared laser pulse mammography is a novel non-invasive imaging technique to improve detection and characterisation of breast cancer, supplementing conventional mammography. Multinational clinical trials will be performed at four European sites on 450patients using improved prototypes of laser-pulse mammographs. For analysis of optical mammograms refined semi-empirical and rigorous mathematical methods will be developed. Through a concerted effort of all clinical and technical partners, scattering and absorption coefficients of normal breast tissue and lesions will be determined to improve the scientific basis of optical mammography. From the results of clinical trials the diagnostic accuracy of laser-pulse mammography will be assessed and compared to conventional mammography techniques.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Sonoelectrochemical Technology of Manufacturing a Bioactive Hydroxypatite Coating on Carbon/Carbon Composites', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

Bone replacement is often required in humans suffering from bone degeneration. Currently the major complication of bone replacement is poor biocompatibility of the implants.Carbon/carbon composites (C/C) have excellent biocompatibility, good endurance in physiological environment and porosity coupled with a modulus that can be tailored to that of a bone, making it an attractive material in the biomedical applications.However, the bioinert C/C composites cannot directly produce or induce the bone tissue regeneration. In this case, introduction of some bioactive coating is an effective and convenient way to make these composites bioactive. Calcium phosphate ceramics, such as hydroxyapatite (HA), have been demonstrated to have good biocompatibility and osteo-conductivity.When the bone implants are used with calcium phosphate coatings, they can combine the mechanical properties of the substrate with the bioactive character of the coating. The main objective of the project is to develop a novel sonoelectrochemic al technology of preparing a bioactive HA coating on the surface of C/C composites.The technology will be developed using the ultrasonic cavitation effect, which generates instantaneous high temperature and high pressure. The mechanism of HA coating format ion will be studied and the biocompatibility of HA coated carbon/carbon composites will be assessed in vitro.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Photo-activated voltage-sensing domain in voltage-sensing proteins' in the context of a Seventh Framework call.

assistant: **Objectives**

Eukaryotic cells have voltage-gated ion channels that are directly activated by voltage but never by light. Voltage-gated ion channels contain a voltage-sensing domain (VSD) that responds to changes in membrane potential by gating the pore domain. VSD are functionally independent domains within canonical voltage-activated ion channels, but are also components of voltage-sensing enzymes and can also form ion channels. Several strategies have been used to enable light regulation of ion channels that are not intrinsically light sensitive and these channels have been successfully used to control neuronal activity (Gorostiza & Isacoff 2007). In the case of voltage-gated potassium (Kv) channels, photoswitchable molecules have been described but they specifically act as covalently tethered channel blockers (Horn et al., 2000). To date, photo-regulation of VSDs has not been reported. Photoswitchable VSD would constitute an exclusive independent structure to remotely control voltage-sensing proteins. We expect voltage-sensing proteins will be rapidly and reversibly activated by light, which has potential use as a noninvasive method to study motion charging shape of VSD in vitro and in vivo. This project aims to develop a new photoswitchable light-activated VSD by incorporating an azobenzene chromophore into the VSD of Shaker Kv channel. Although the X-ray crystallographic structures of prokaryotic and same as eukaryotic potassium channels were recently published, the position and the molecular movement of the voltage sensor in the activated or deactivated state are still controversial. As a long term aim of this project, this approach could be extended to the recently cloned and described VSD proteins such as Ci-VSP and Hv1 (Murata el al., 2005; Sasaki et al., 2006; Ramsey et al
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'ESTABLISHING A COMPREHENSIVE UNDERSTANDING AND TAXONOMY OF CHILDREN'S DIGITAL MATURITY' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The overall goal of DIGYMATEX is to provide evidence-based tools that will assist in understanding and measuring children’s digital maturity. These tools are intended to be used e.g. by families, schools, and policy stakeholders. The first tool is the development of an innovative and market-ready instrument - the Digital Youth Maturity Index (DYMI) – as a cloud-based open-access tool in order to establish and implement a comprehensive understanding and taxonomy of children’s digital maturity leading to the prediction and explanation of benefits and risks regarding children’s ICT-related behaviour. The Digital Youth Maturity Index will act as a measurement tool for classification and segmentation of user groups as well as a behavioural prediction tool based on machine-learning techniques. The second tool is the development and application of the DiGYou-program - a technology-related solution and recommendation program, which is based on as well as supports the application of the DYMI. The two innovative tools will directly target the main impact goals associated with the call. With the Digital Youth Maturity Index (DMYI), the project will be able to develop and implement a comprehensive taxonomy, which will inform relevant stakeholders and practitioners on the long-term effects of ICT on child behaviour. Furthermore, with the DMYI in combination with the DigYou3-program, we will develop concrete solutions in order to contribute to a safer and more beneficial use of digital technologies by children and we will be able to formulate recommendations in support of national and European policies in the field. DYGIMATEX - builds on an inter-disciplinary, multi-method approach by integrating expertise, methods and knowledge from different research areas like business management,