RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Adaptive Separation using Dynamic Nanofibril Networks' to be submitted under Horizon Europe.

assistant: **Abstract**

This research program will develop materials, methods, and technologies that enable adaptive separation of molecules and particles using dynamic nanofibril networks. The ground-breaking nature is the development of dynamically tunable membranes/gels for next-generation separation technology. Current separation technologies are based primarily on polymeric membranes or gels for membrane filtration or chromatography. Membrane filtration is versatile but lacks selectivity, while chromatography is selective but with limited throughput. As pharmaceutical companies move toward protein or nanoparticle-based therapies, the size limitation of chromatography is a concern. The future separation technology should be adaptive and selective, with high resolution and throughput. It is time to develop next-generation separation technology that enables dynamic adaptability and integration with our electronic infrastructure and AI technology.Hydrated nanofibril networks with unique nanomechanical behavior, a vast dynamic density range, and large pore sizes enable tunability that polymer networks cannot achieve. It is an unexplored class of materials for separation purposes, now available at scale due to recent cellulose and amyloid nanofibrils developments. Nanofibrils assemble in anisotropic hydrogel networks with a uniaxial swelling, ranging from 0 to 1000 g/g water content with pore sizes from a few to 1000 nm. I will study how different pretreatments or stimuli, such as electrochemistry, enable direct control of this 1000-fold change in pore size, which is unachievable for polymers. I will explore different modes of separation: centrifugation, filtration, electro-filtration, and ion-selectivity, using nanofibril networks as an adaptive mesh to sieve/repel molecules and particles of d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Rapid antibiotic detection for illegal and unlicensed substances in animal feedingstuffs' (FEEDSTUFFS-RADIUS).

assistant: **Concept**

In the EU, human health concerns have resulted in the antibiotic growth promoters avoparcin, spraying, tylosin, virginiamycin and zinc backtracking being banned from use in animal feeding stuffs. Existing Community methods of analysis" are microbiologically based, non-specific, susceptible to feed component interference and unsuitable for effective policing of the ban. New screening and confirmatory tests are required. Firstly, immunoassay dipstick tests will be developed. Using the novel idea of antiidiotype monoclonal antis era as surrogate legends, carbon labelled monoclonal antis era, raised to each drug, will be employed in a competitive assay format resulting in robust, reliable & highly specific assays, less susceptible to interference than previous immune- or microbiological assays. Secondly mass spectrometric confirmatory techniques will be developed, allowing unequivocal identification/quantification of each antibiotic. Collaborative testing will establish their usefulness as definitive EUmethods of analysis. This twin-track approach will facilitate the effective implementation of EU policy."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'RNA regulation during viral infection'.

assistant: **Concept**

Viral infections are responsible for significant morbidity and mortality and frequency and impact of epidemics are expected to increase. Thorough understanding of basic virology is critical for informed development of prevention and control. Most systematic studies of virus-host interactions have focused on proteins, however, with recent methodological advances the intersecting fields of viral infection and RNA biology hold great promise for basic and therapeutic exploration. The goal of this application therefore is to discover and dissect RNA-based virus-host interactions and related regulatory mechanisms of gene expression.Micro-RNAs (miRNAs) fine-tune gene expression by repressing mRNA targets. However, cellular miRNAs increase translation and replication of certain viruses. Thus, hepatitis C virus (HCV) critically depends on the liver specific miR-122, which emerged as a therapeutic target. Further, HCV sequesters enough miR-122 to indirectly regulate cellular gene expression. I hypothesize that this RNA-based mechanism contributes to virus induced liver cancer, and aim to address this using our recently developed rodent model for HCV infection (Aim 1). Better understanding of viral RNA (vRNA) interactions could significantly contribute to basic infection biology and novel therapeutics. I therefore aim to systematically identify vRNA interactions with other cellular RNAs and proteins (Aim 2). I expect to identify interactions of value for functional regulation and therapeutic targeting. I finally hypothesize that translation of certain cellular mRNAs – similarly to viruses – increase upon miRNA binding, and aim to systematically screen for such virus-like alternative regulation, with potential to change understanding of post-transcriptional regulation (Aim 3).In co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'The institutional dimensions of global change: from scoping report to science plan' (1994-1998).

assistant: **Innovation**

RTD actions implementing ENRICH are part of accompanying measures of the Environment and Climate Programme, the Marine Science and Technology Programme and the International Cooperation Programme. CORDIS generally does not held information on accompanying measures of RTD programmes. Therefore for further details please contact: Ib Troen, European Commission, DGXII.D.I at ib.troen@ec.europa.eu.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'A mimetic implant for low perturbation, stable stimulation and recording of neural units inside the brain.' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Developing brain implants is crucial to better decipher the neuronal information and intervene in a very thin way on neural networks using microstimulations. This project aims to address two major challenges: to achieve the realization of a highly mechanically stable implant, allowing long term connection between neurons and microelectrodes and to provide neural implants with a high temporal and spatial resolution. To do so, the present project will develop implants with structural and mechanical properties that resemble those of the natural brain environment. According to the literature, using electrodes and electric leads with a size of a few microns allows for a better neural tissue reconstruction around the implant. Also, the mechanical mismatch between the usually stiff implant material and the soft brain tissue affects the adhesion between tissue cells and electrodes. With the objective to implant a highly flexible free-floating microelectrode array in the brain tissue, we will develop a new method using micro-nanotechnology steps as well as a combination of polymers. Moreover, the literature and preliminary studies indicate that some surface chemistries and nanotopographies can promote neurite outgrowth while limiting glial cell proliferation. Implants will be nanostructured so as to help the neural tissue growth and to be provided with a highly adhesive property, which will ensure its stable contact with the brain neural tissue over time. Implants with different microelectrode configurations and number will be tested in vitro and in vivo for their biocompatibility and their ability to record and stimulate neurons with high stability. This project will produce high-performance generic implants that can be used for various fundamental studies and applications, inc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'IRIS.AI: The Artificial Intelligence-powered R&D assistant' under Horizon 2020.

assistant: **Concept**

More than 4000 research papers are published every day. Sadly, our human brains can only process a fraction of this knowledge. As a result, 50% of papers published are read by less than three people and as many as 90% of papers published are never cited. Currently, researchers rely on a lengthy manual process when reviewing scientific literature or trying to find a solution to a complex questions, generally only looking for papers within their expertise area, when the answer may be in an unrelated area.At Iris AI AS, we decided to overcome such challenges by giving birth to Iris.ai, the first Artificial Intelligence-powered researcher. Iris.ai uses a neural network algorithm to understand context and document similarity. It automates the process of finding relevant scientific literature and creating new hypothesis, saving up to 90% time of the research process and increasing accuracy with a 85% precision. As a result, it will accelerate the progression of knowledge and problems solving.Iris.ai is quickly becoming effective thanks to our team of data scientist experts and the invaluable help from our community of AI trainers, who aid Iris.ai make sense of science. Iris.ai is also becoming famous! We have been featured in the $5M IBM Watson AI XPRIZE or the prestigious Science journal and were selected by Fast Company in 2017 as one of the top 10 most innovative companies in AI (sharing ranking with Google, IBM and Baidu). Furthermore, we have big corporate clients such already on board. With Iris.ai, we will be first targeting the materials science R&D market, estimated to be worth €85 billion by 2024 and growing at a 10.4% CAGR (period 2015-2024) although our long-term goal is R&D at large globally valued at €1400 billions per year. By using a freemium business model ap
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Wireless Tissue Engineered Bioelectronics integrating a dual-mechano-electrical Therapy for Volumetric Muscle Loss' in the context of a Horizon Europe call.

assistant: **Objectives**

Volumetric muscle loss (VML), or a frank loss of muscle tissue often results in a permanent loss of muscle tissue and chronic reduction in strength, which can lead to long-term disability. Tissue engineered biomaterial matrix (e.g. hydrogels) offers a promising strategy to restore and improve the function of VML injuries and regeneration. However, muscle regeneration cannot succeed in the absence of biophysical (e.g. mechanical force, topography, and electrical induction) and/or biochemical cues (e.g. integrins) from the extracellular matrix. The matrix design must take into account the functional characteristics of the target tissue. For example, the structural anisotropy in muscle is critical in guiding cell organization and generating powerful muscle contractions. Recently, mechanotherapy has drawn the attention of physical therapists, which is a strategy for tissue repair and remodelling through a conversional process from mechanical signals into biochemical response in cells. Moreover, muscle is responsive to electrical stimulation due to its physiological nature. Bioresorbable wireless bioelectronics as electrical stimulators have been developed for many applications, including neuromuscular regeneration, and cardiac pacemakers etc. Inspired by these, I aim to develop a novel anisotropic matrix with mechano-responsive properties, followed by integration with bioelectronics, which will provide a dual-mechano-electrical therapy for VML. To achieve this, I will carry out the project employing an interdisciplinary approach, including polymer chemistry, physics, electronic engineering, mechanobiology, and regenerative medicine. My experience in polymer chemistry, physics, and mechanobiology will be integrated with the outstanding expertise of the Northwestern Universit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'TalkingHeads: Audiovisual Speech Recognition in-the-wild' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Audio-visual speech recognition refers to the problem of recognizing speech using both audio and video information. Speech is not a purely auditory process but the way that the listener perceives it is also through the recognition of the visual patterns associated with the mouth movement. This correlation of the audio-visual information has been occasionally explored in literature in order to develop more robust automatic speech recognition systems for cases in which the auditory environment is noisy (e.g. background noise, multiple speakers). However, the problem of audio-visual speech recognition has been mainly studied in controlled, laboratory conditions. TalkingHeads proposes, for the first time, the problem of audio-visual speech recognition in unconstrained (in-the-wild) videos collected from real-world multimedia databases and a set of methodologies that will work well under the assumed in-the-wild setting. TalkingHeads brings together a talented but experienced researcher (ER) with expertise in speech analysis (diarization and recognition) and the Supervisor with large research experience in Computer Vision for face analysis in-the-wild (recognition, detection, alignment and tracking, and facial expression analysis). TalkingHeads will establish the ER as an independent and internationally recognized researcher in the area of audio-visual fusion and speech recognition. Through TalkingHeads’ achievable work plan, the ER will attain a high level of research maturity by (a) complementing his expertise on speech analysis through extensive training in Computer Vision, (b) conducting research on a challenging research problem (audio-visual speech recognition in-the-wild) with significant career opportunities in both the academia and the industry, (c) publishing at hig
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Improving the well-being of elderly patients via community pharmacy based pharmaceutical care', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

- To develop a standardised community pharmacy based pharmaceutical care programme (education and monitoring) for the prevention of drug related problems in elderly patients- To evaluate, in a controlled multicentre trial in several EU countries, the outcome of the interventions on the quality of care (including health related quality of life) of a targeted group of at risk" elderly patients and on the costs of their healthcare.Pharmaceutical Care is a new approach to the delivery of pharmaceutical services to patients. It involves the active participation of the pharmacist in the treatment of the patient through involvement in structured education and monitoring activities. The overall aim of "Pharmaceutical Care" is to decrease the number of drug related problems experienced by patients and thereby improve their quality of life. It has been well established that elderly patients (65 years+) are more likely to suffer from chronic illness than their younger counterparts, receive a disproportionate number of medicines and therefore suffer from a greater number of drug related problems. The aim of the present study is to evaluate, in a multicentre international investigation within the EU, the benefits and cost-effectiveness of a harmonised, structured community pharmacy based intervention programme to improve the care of elderly patients. It is hypothesised that improved pharmaceutical care of elderly patients can help prevent serious drug related problems arising and could therefore save considerable sums of money as well as improving the quality of life of these patients. The study will be carried out in seven EU countries and will involve a minimum of 12 pharmacies (half control sites and half intervention sites) per country and a minimum of 40 patients per pharmacy w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Preparation and Distribution of the Clean Coal Technology Newsletter No16, 17 And 18' (1998-2002).

assistant: **Concept**

The aim of this action is to continue as so far successful activity: the publication of the CLEAN COAL TECHNOLOGY NEWSLETTER, to be published in 4.000 copies in English, and widely distributed both by mail and INTERNET. The newsletter will be issued each four month. The newsletter is a form of dissemination which offer relevant information on European Clean Coal Projects and all relevant news about these technologies, to a wide range of decision makers: Utilities managers, technicians and R&D groups; politicians, planners, financiers; specialised and general press. A non excessively technical language will be used so that all targeted groups will grasp the messages conveyed each Newsletter.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'POSTBURNING SYSTEM FOR BOTTOM ASH IN LIGNITE BOILER', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The aim of the action is to increase the boiler efficiency by reducing unburnt content in bottom ash in Unit 3 of Megalopolis Power Plant by installing a dry bottom ash postcombustor to strongly reduce the unburnt material still present : this post combustion will take place directly under the furnace in the stainless steel extraction belt by creating a high reactivity thanks to the high temperature and the oxidizing atmosphere.The high temperature is reached by properly insulating the zone under consideration and controlling the quantity of the incoming air (enough to have a zone reach in oxygen but not too much so as to avoid excessive cooling); at the same time the belt velocity will be controlled to have enough residence time for the ash to burn : the expected result is to reduce the unburnt material in bottom ash to 40% of the present value.The following results are expected from the application of the system :- boiler efficiency improvement of around 1.4% with the consequence of increasing the power generation during full load periods and reducing the fuel consumption during the reduced load periods- strong reduction of the water requirement from the power station, by the complete elimination of any water need from the system- strong reduction in the environmental pollution by complete elimination of any water discharge from the bottom ash system- reduction in the amount of solid byproduct (bottom ash) thanks to the reduction of water content and of the unburned carbon content- increase of the potential of ash reusing in the building industry thanks to the reduction in the unburned carbon- strong improvement of the bottom ash system reliability (presently low in Megalopolis)The project will be implemented in the Unit 3 of Megalopolis Power Station. The bottom ash