RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Co-creation of service innovation in Europe' (CoSIE).

assistant: **Concept**

There is growing consensus that public services can be improved through experiments which bring together service providers and their users. This proposal is for H2020-SC6-Co-Creation-2016-217: Applied co-creation to deliver public services. The CoSIE project contributes to democratic dimensions and social inclusion through co-creating public services by engaging diverse citizen groups and stakeholders. Utilizing blended data sources (open data, social media) with innovative deployment of ICT (data-analytics, Living Lab, Community reporting) in nine pilots, the project introduces the culture of experiments that encompasses various stakeholders for co-creating service innovations. The CoSIE project has two overarching aims: i) advance the active shaping of service priorities by end users and their informal support networks, ii) engage citizens, especially groups often called ‘hard to reach’, in the collaborative design of public services. The aims are divided into six objectives: 1) develop practical resources grounded in asset based knowledge to support new ways for public service actors to re-define operational processes, 2) produce and deliver nine real-life pilots to co-create a set of relational public services with various combinations of public sector, civil society and commercial actors, 3) draw together cross-cutting lessons from pilots and utilise innovative visualisation methods to share and validate new ideas and models of good governance, 4) apply innovative approaches appropriate to local contexts and user groups to gather the necessary user insight to co-create services, 5) ensure sustainability by establishing local trainers for animating dialogue and collating user voice, embedded in community networks, 6) mobilise new knowledge from piloting and validati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Characterization of the mechanisms controlling Intestinal Stem Cell specification and positioning. Use of Intestinal Stem Cells for tissue regeneration' (2002-2006) targeting Sixth Framework.

assistant: **Abstract**

The intestinal epithelium represents one of the richest and easy reachable sources of adult Stem Cells. Each of the million crypts that decorate the intestinal mucosa contains a handful of adult Stem Cells with unlimited capacity of self-renewal. Yet its u se has been hampered by the lack of knowledge regarding the programs and pathways controlling their maintenance and specification. Recent data indicate that Wnt signalling might play a general role in Stem Cell specification as that it is essential for Intestinal Stem Cell renewal. Here we propose to study further these questions into three steps or objectives. First, we intend to establish long term intestinal stem cell cultures and to study their potential in the regeneration of other tissues. Second, we propose to identify and characterize the core beta-catenin/Tcf genetic program (effector of Wnt signalling in the nucleus) driving specification or maintenance of diverse types of embryonic and adult Stem Cells including Intestinal Stem Cells. Third, we wi ll characterize the mechanisms of intestinal cell positioning at the bottom of the crypts and the role of cell repulsion mediated by Eph and ephrins - two beta-catenin/Tcf targets - in controlling cell sorting in the intestinal epithelium.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Neighborhood effects on early school leaving in Ireland' in the context of a Sixth Framework call.

assistant: **Objectives**

Few events in the adolescent life course determine subsequent social and economic opportunities more than dropping out of school. Given the importance of education for personal success and social inclusion, it is not surprising that there is a large amount of research examining the causes and consequences of early school leaving. In Ireland, this research has primarily focused on either the role of family or school characteristics without directly addressing the influence of the neighbourhoods in which students live.This research will incorporate a more ecological approach to the examination of early school leaving by incorporating state-of-the-art spatial analysis and multi-level modelling to assess the role of neighbourhood effects on the odds of students dropping out of school. In addition, this research will assess the extent to which the spatial pattern of early school leaving has varied through time and if the effects of neighbourhood are also sensitive to change over time. The value of incorporating an explicitly spatial approach to examining early school leaving in Ireland is twofold. First, it provides important new insights that will help inform future policy to mitigate early school leaving. Second, Ireland's size makes it possible to undertake a national-level study that will allow urban-rural differences in neighbourhood effects to be addressed, which will add greatly to the current research on the role of place in determining social outcomes.This research will also provide a vehicle for co -operation between the National University of Ireland, Galway (NUIG) and other research agencies in the country, including the Economic and Social Research Institute, the Higher Education Authority and the Combat Poverty Agency. In addition, it will provide an important
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Computational study of membrane bound parts of the ATP synthase' (ISISATPSYNTHASE), addressing dissemination and exploitation.

assistant: **Impact**

We will perform a computational study of selected properties of the membrane bound part of ATP synthase, the protein responsible for the synthesis of ATP. The objective of this proposal is to achieve training in the interdisciplinary field of molecular dynamics simulations of proteins through research in a project that is of both fundamental and practical importance. The research plan includes the study of:a) the conformational change of the subunit c;b) the rotation of the subunit c ring;c) the pathway for the proton translocation in the ATP synthase;d) the interaction of the Fo complex with the F1 complex;e) the rotation of subunit gamma driven by Fo.We will use the CHARMM computational framework for the study of biomolecules together with tools developed at the host laboratory and related visualisation programs. We will build models using the published NMR structures of two subunit c conformations and the low-resolution X-ray structure of the subunit c ring, so as to be able to insert the ring into a model membrane. We will analyse the conformational change of the subunit c by means of reaction path techniques and molecular dynamics approaches. We will perform normal mode, electrostatic, and free energy analysis of selected conformations of the individual subunits and the entire ring. We will model the combined Fo F1 complex based on the known structure ofF1 and the model of Fo.The computational study of biomolecules is a new direction of study for the researcher. His background in computational materials science methodologies will need to be complemented with the concepts and methods of protein dynamics. He will become fully engaged in the progress of this multidisciplinary field and will use the latest information from structure determination, mutation, and cross-l
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'inVestigation of distributEd propulsion Noise and its mitigation through wind tUnnel experiments and numerical Simulations' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Distributed Electric Propulsion (DEP), is one of the propulsion configurations that, taking advantage from the Distributed Propulsion concept, is believed to exploit the benefits of electrical engines to drastically reduce fuel consumption and emissions. In the framework of the topic JTI-CS2-2018-CFP10-THT-08, the proposal VENUS will have the objective to understand the physics behind the aeroacoustics of DEP through a deep theoretical, experimental and numerical study. Appropriate numerical procedures for DEP noise assessment will be set-up and experimental data-set obtained in dedicated wind tunnel tests, will be used both as experimental DEP noise validation reference and for providing support to the identification of the main parameters affecting DEP noise. Technologies for DEP noise reduction will be studied as well and tested experimentally. From the technical standpoint, the VENUS consortium will support the model design, manufacturing and integration by realizing a representative test article for WT parametric aeroacoustic tests, able to allow for configuration changes, in terms of engine-wing and engine-engine installation configurations, and to test the selected noise mitigation technologies. The consortium will develop methods and tools enabling a concurrent aerodynamic and aeroacoustic design of DEP configuration aircraft. The final step will consist in the experimental-numerical assessment of the numerical models. As a practical achievement, the study will support the design of a new regional aircraft configuration, in terms of wing and engines’ installation, to target a DEP which is optimized in terms of aerodynamic and aeroacoustic performance. It is pointed out that all the produced models, data and documents will be open access for other institutions, w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Fundamental Understanding of Solar Driven Interfacial Evaporation using 3D hierarchical hybrid structures' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Facing water scarcity that affects two-thirds of the global population, our planet's demand for sustainable solutions has never been more critical. Solar-driven interfacial evaporation (SDIE) is a promising method to produce fresh water using solar energy. Despite many advancements in material development, the fundamentals of interfacial transport have been left untouched. With localized heating proximate to the interface, SDIE departs from conventional evaporation mechanisms by creating pronounced temperature and pressure gradients proximate to the interface, substantially affecting liquid-vapor interactions. This distinction prompts reevaluating traditional models and concepts, highlighting the pressing need for an updated framework. With its primary objective as crafting a transport scheme for accurate interfacial flux predictions, I will examine SDIE using concurrent advanced microscopic thermography, fluorescent, and optical imaging techniques along with computational fluid dynamics (CFD) and theoretical approaches to reveal uncharted dimensions of desalination. SolWator proposes innovative 3D patterned hybrid structures that provide optimum hydrothermal conditions for maximum evaporation from liquid meniscus. This will be accompanied by the formulation of updated CFD and theoretical models to understand the effects of localized intense heating on the coupling of interfacial heat/momentum transport and vapor diffusion in SDIE. With SolWator identifying bottlenecks, it provides optimization guidelines and sustainability studies. The outputs address one of the most pressing challenges of our time, making SDIE highly feasible for clean water shortage challenges and enhancing the socio-economic facets of our global community. The predictive tools and the knowledge gain
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Toward new era of quantum electrical measurements through phase slips' under Horizon 2020.

assistant: **Concept**

We will exploit new macroscopic quantum phenomena realised in superconducting nanowires made from 2D superconductors to trigger a paradigm change in electrical metrology. Our overall objective is to develop a robust and easy-to-use universal electrical quantum standard on a single chip by utilizing the duality of superconductive physics, which will allow direct traceability to the SI with no recourse to long calibration chains. Our main specific objective is to demonstrate a proof-of-concept quantum current standard using coherent quantum phase slips in superconducting nanowires (SNW). This effect is quantum-mechanically dual to the Josephson effect (which can be realised in the same superconductors) but yields quantised current reference rather than voltage. The exact duality suggests that the new current standard can be operated with the same user-friendly infrastructure and reach similar robustness and accuracy as the Josephson voltage standard. Such science-to-technology breakthrough can bring quantum-enabled accuracy directly to the end users. The combination of current and voltage standards - duals of each other - will enable all electrical quantum standards on a single chip.Previous tentative experiments with SNW electronics encountered two general problems: sensitivity to the electromagnetic (EM) environment and SNW fabrication irreproducibility. We will solve these problems by unprecedented control of SNW. In particular, we will demonstrate gate-tuneable quantum phase slips in SNWs based on 2D superconductors and develop a tuneable EM environment for SNWs by using complementary metal-oxide semiconductor (CMOS) technology. These objectives will also lay foundations for future dual superconducting electronics, where SNW becomes a standard circuit element like Jos
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Quantitative Imaging of Liver Fibrosis and Fibrogenesis' under Seventh Framework.

assistant: **Concept**

Chronic liver disease can progress to cirrhosis, with death due to liver failure and cancer. Cirrhosis prevalence in the EU is 0.5%-1%. However, development of therapies that prevent progression to cirrhosis is hampered by the lack of a sensitive, non-invasive method to quantify fibrosis or fibrosis progression (fibrogenesis). Liver biopsy 1) is risky, 2) shows high sampling variability, and 3) is too insensitive to assess fibrosis progression in clinical studies. Conventional radiological imaging, serum markers, and ultrasound- or MR-elastography do neither permit exact fibrosis nor any fibrogenesis measurement.We plan to develop a clinically applicable methodology to quantitate fibrosis and fibrogenesis over the whole liver using imaging agents that target and thus quantify abundant fibrillar collagen or key cells that drive fibrogenesis (activated myofibroblasts and cholangiocytes). We demonstrated the feasibility of this approach using radiolabeled conjugates of high affinity that target integrin alphaVbeta6 and PDGFbeta receptor that are cell surface molecules of activated cholangiocytes and myofibroblasts. i.v. injection of the integrin conjugate allowed quantitative imaging of alphaVbeta6 expression and correlated with whole liver fibrogenesis. We intend to optimize nonpeptide and peptide ligands for integrin alphaVbeta6, PDGF beta receptor and fibrillar collagens using novel linkers and oligomerization, using PET-radioimaging with Ga-68, Sc-44 and F-18. The targeted imaging constructs will be validated in vivo using established rodent models with defined liver fibrosis and fibrogenesis, with and without antifibrotic drug therapy. Translation to phase I and II clinical studies is planned in years 4-5 of the project.The technology will for the first time allow for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'No Sword Bites So Fiercly as an Evil Tongue? Gossip Wrecks Reputation, but Enhances Cooperation' in the context of a Horizon 2020 call.

assistant: **Objectives**

Social norms in general, and norms of cooperation in particular, are the cement of all human societies. For the difficult problems of the maintenance and enforcement of social norms and of cooperation, humans have developed surprisingly complex solutions. Reputation mechanisms and gossip are certainly among the compound informal solutions.According to common wisdom, gossip channels mainly negative and often fictitious information. If it is so, how can dishonest gossip and the resulting biased reputations legitimize social order and promote cooperation? This is the main puzzle we tackle in the proposed project exploiting a wide scale of instruments. We use analytical modeling and agent-based simulation to derive hypotheses. We test simple hypotheses in small group experiments. We develop new methodological tools to appropriately analyze the triadic nature of gossip embedded in network flows of information. We utilize dynamic network datasets from primary and secondary school classes, and we gather qualitative and quantitative information from organizations to test conditional hypotheses about the role that gossip plays in reputation and cooperation in different developmental and social contexts of life. In addition, we apply new communication technologies currently under development to explore the hidden world of gossip and the dynamics of reputations in dormitories and organizations.With the insights gained, we can overcome common stereotypes about gossip and highlight how gossip is related to credible reputational signals, cooperation, and social order. Expected results will help us to outline the conditions that can promote cooperativeness in work groups, and they will help to construct successful prevention strategies of social exclusion and other potentially harmful
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Non-Intrusive Resident Identification Sensor' in the context of a Horizon 2020 call.

assistant: **Objectives**

The goal of Non-Intrusive Resident Identification Sensor (NIRIS) project is to introduce the first affordable NIRIS to the market, which is the key component to enable true intelligence in smart buildings. Currently available smart buildings rely on user input and manual micromanagement to function correctly, which is neither efficient nor user friendly. Our sensor, on the other hand, non-intrusively identifies users passing through a doorway, which enables automatic adaptation and optimization of house appliances management, i.e. true smart buildings.Moreover, an array of NIRIS sensors can monitor users’ room-level location and detect anomalies, increasing safety and security of inhabitants and enabling a range of new applications, e.g. tele-medicine. Artificial intelligence method embedded in our NIRIS (developed in E-doorman project) accurately predicts users’ room-level location based on past behaviour. User-presence prediction can be used to lower household’s running costs by up to 30% and at the same time increase comfort of inhabitants. This means more than €300 in savings for an average European household per year. We intend to sell our sensor for less than €50 per unit, at an average of 3 sensors per house; this means that consumer’s payback period will be less than 6 months.All required intellectual property rights (IPR) are owned by Elgoline or are in public domain; the most important IPR is already protected by a patent filed on July 30th 2014 at the Slovenian patent office. Within the NIRIS project we will analyse opportunities for sensor applications, elaborate on business plan and connect with appropriate partners to bring NIRIS to the masses.