RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Bioprocess Platform for the A. sojae PGzyme system' (2007-2013).

assistant: **Concept**

PGSYS is an integrated platform for the biosynthesis, tailoring, and final application of the unique pectinase complex from A. sojae, particularly in –but not limited to- the European Food, Beverages, and Environmental industry. PGSYS was born 4 years ago from the pioneering work of Dr. Canan Tari, at Izmir Institute of Technology (Turkey), and further funded by German-Turkish Bodies, and by the EU within the EuroTransBio-3-Scheme. This has resulted in a network of scientist working on the project, including public and private partners, particularly SMEs. In the present project, the partners are proposing joint research and training activities, workshops, and other networking activities with the aim of exploiting complementary expertise with Latin-American and Mediterranean Countries. As a result of such complementarities and synergies, additional benefits in terms of transfer of knowledge and skill are anticipated.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Linking genome variation with haplotype-resolved sequencing' to be submitted under Horizon Europe.

assistant: **Abstract**

DNA sequencing has transformed biological research, and is fast becoming the standard-of-care in medicine. Chances are good that every European person born today may have their genome sequenced at some point in their lifetime (it is already happening in Iceland). The currently prevailing sequencing platform, Illumina short-read sequencing, prioritizes content (DNA basepairs) over preserving long-range haplotype context. This decision has paid off so far, but comes at the cost of complicated analyses and often lead to undetected disease-causing chromosome rearrangements. Alternative long-read technologies, however, have yet to deliver the scale and throughput to truly take over from Illumina sequencing. To meet the grand challenge of sequencing humanity and biodiversity, we need both content and context. As part of our ERC StG action, we have invented haplotagging, a technique that restores haplotype context while integrating seamlessly into Illumina sequencing. We have previously published a small-scale pilot study that haplotagging can deliver superior results at a fraction of existing costs. In doing so our team have solved a series of molecular engineering and computational challenges that have stumped far larger parties. However, our prototype dataset are still not large enough to fully allay concerns from potential licensees regarding robust scalability. Thus, we propose to generate a mid-scale, 2000-sample pilot with direct support from Illumina to provide additional benchmark data, guide scale-up efforts and inform decision-making by industry and academic stakeholders. We expect this proposal will help transition haplotagging from a research concept towards the market.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'A bio-inspired self-dislodging approach of ice' (BSAI) targeting Horizon Europe.

assistant: **Abstract**

Novel and efficient anti-icing/de-icing methods should be continuously explored because ice accumulation has dramatic adverse effects on human activities. Traditional thermal de-icing, as an active technique extensively used in the industry, requires enormous energy input and may deteriorate the functionality of wall material such as epoxies or resins if the temperature is too high. Passive de-icing methods cannot work alone for safety concerns, although they do not require external energy inputs. Therefore, there is an urgent need to integrate the active de-icing method with the passive one, leading to a hybrid anti-icing/de-icing approach. Inspired by natural creatures who usually use their surface structures to realize directional liquid transport for survival, a spontaneous self-dislodging approach of ice is proposed by artificially varying the surface wettability without external energy input. The de-icing performance of this method can be further enhanced by imposing a temperature gradient. Compared with the traditional thermal de-icing method, the required de-icing time can be reduced by more than 90% based on the applicants test cases of this novel hybrid anti-icing/de-icing method that has not previously been proposed. A mathematical model that will be validated by performing Molecular Dynamics (MD) simulations will be built to quantify the effects of wettability and temperature variations on the de-icing performance of this novel method. This work will shed light on the design of intrinsically icephobic materials.


**Keywords:** Anti-icing, de-icing, Molecular dynamics simulation, Hydrodynamics, Thermaldynamics
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project '3D Volumetric Video Capturing and Streaming Software- SPACEPORT' (SPACEPORT) under Horizon 2020.

assistant: **Objectives**

Spaceport is a media server capable of capturing and streaming 3D live media. Streaming media is more popular than ever and video streaming registered the highest growth. Until recently the media content, such as sport matches, concerts, live events, has been delivered is in 2D format but as the improvement in the Virtual Reality technology speeds up, 2D contents will be obsolete very soon.There are 2 main techniques in VR technology: First one is the 360°, the method most commonly used today. Second one, which is a very new technology, is 3D Volumetric Video Capturing technique. Our product Spaceport has been developed with this newest technology and it is the only product-to-be, which is very close to the market, that can capture and stream 3D content based on volumetric video capturing technology.  3D Volumetric capture, is expected to surpass 360° solutions very soon. The main advantage Volumetric video differs from traditional VR or 360° video is that it offers a truly three-dimensional viewing experience. With existing 360° videos today, audience’s view is locked to a single vantage point. There is no depth of field. Unlike real-time rendered VR games, spectator can’t walk around inside the video. In 3D format, a spectator in VR is able to physically look and move through the scene. In 360-degree video, audience is stuck with the location. Everything’s fixed. With volumetric everything’s possible.Although our product can be used for various purposes such as trainings, presentations, communication, medical education, and live events, we chose to enter with the media & entertainment sector as it has the highest potential in terms of growth and profitability. The total size of the video market is USD 30.29 Billion in 2016 and this value is expected to reach USD 70.05
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Multimodal, Efficient Transportation in Airports and Collaborative Decision Making""'.

assistant: **Innovation**

The objectives of META-CDM (Multimodal, Efficient Transportation inAirports and Collaborative Decision Making) are to study theconditions under which Collaborative Decision Making, which has beenso successful at enabling advanced air transportation concepts such asground delay programs and airport departure managers, can help airtransportation stakeholders deal with major disruptive events thataffect civil aviation. Crisis events cause the air transport systemand society huge cost and the passenger bears the practicalconsequences. This project will take an integrated look at theeffectiveness of airside and landside CDM and its effectiveness inminimizing the impact upon the traveler. In this work, the passengerbecomes the center of attention, and the goal is to make his journeyas short and as efficient as possible, beginning when he leaves hisliving or working quarters at his origin location and ending when hedrops his luggage at home or at the hotel. The possible impediments totravel are highly disruptive events, such as strong snow storms,volcano ash clouds or labour unrest. We will examine the coherence andco-ordination of the many systems that are part of delivering thetraveler through an airport and, when crisis hits, how wellcontingency plans can help to minimize penalties to the passenger. Thepassenger-centric approach also looks at how alternative transportmodes and communication can step in during crisis situations tominimize personal disruption.This study will deliver a broad understanding of systems strengths andweaknesses, the areas where co-ordination can be improved and anassessment of the implications of disruptive events from manyperspectives. It will also deliver a comprehensive update onairside-CDM throughout the world. Clear messages in these areas wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Transverse, Intrafascicular Multichannel Electrode system for induction of sensation and treatment of phantom limb pain in amputees' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Amputation of a limb is a surgical intervention used as a last resort to remove irreparably damaged, diseased, or congenitally malformed limbs where retention of the limb is a threat to the well-being of the individual. The procedure traumatically alters the body image, but often leaves sensations that refer to the missing body part, the phantom limb. In 50-80% of cases, these sensations are painful and currently, there are no effective treatment modalities. Given sufficient control over a large number of nerve fibers, a neural interface may be able to artificially evoke sensations of touch, or counteract the phantom limb pain. The application of Micro/nano technologies with functional electrical micro stimulation can not only pave the road towards a treatment, but also also provide amputees a means to sense virtual environments directly. The ultimate aim of this project is to develop this novel Human Machine Interface (HMI). A novel microfabricated neural interface, the Thin-film Intrafascicular Multichannel Electrode array, and implantable multichannel stimulator system will form the key core technological developments in the project. The work is structured in 10 work packages in three phases. The technological development phase will model, design, manufacture and characterize the multi-channel electrode (TIME) and design, manufacture and test an implantable, multi-channel stimulator. In vivo characterization phase will evaluate the TIME electrodes for biocompatibility, stability and chronic safety in animals and develop a psychophysical test platform for system integration. Finally, pre-clinical evaluation will test the system in short-term implants in amputee subjects. The work will provide direct contribution to the next-generation smart systems in the ICT-2007.3.6
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Dynamic protein-DNA interactomes and circadian transcription regulatory networks in mammals' in the context of a Seventh Framework call.

assistant: **Objectives**

The aim of this project is to understand the dynamics of protein-DNA interactomes underlying circadian oscillators in mammals, and how these shape circadian transcriptional output programs. Specifically our goal is to solve a fundamental issue in circadian biology: the phase specificity problem underlying circadian gene expression. We have taken a challenging and original multi-disciplinary approach in which molecular biology experiments will be tightly interlinked with computational analyses and biophysical modeling. The approach will generate time resolved protein-DNA interactomes in mouse liver for several key circadian repressors at unprecedented resolution. These experiments will be complemented with chromosome conformation capture (3C) experiments to monitor how looping interactions and 3D genome structure rearrange during the circadian cycle, which will inform on how circadian transcription networks use long-range gene regulatory mechanisms. Novel computational algorithms based on biophysical principles will be developed and implemented to optimally analyze interactome and 3C datasets. For the latter, statistical models from polymer physics will be used to reconstruct the chromatin networks and interaction maps from the 3C data. At the detailed level of individual cells, we will investigate transcription bursts, and how those are involved in the control of circadian gene expression. In particular we will exploit high temporal resolution bioluminescence reporters using a biophysical model of transcription coupled with a Hidden Markov Model (HMM). Through our innovative approach, we expect that the data generated and state-of-the-art analyses performed will lead novel insight into the role and mechanics of circadian transcription in controlling circadian outputs in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'ZNMF Pulsed Jet-based Active Flow Control of the UHBR-induced Flow through High Fidelity CFD' (X-Pulse) targeting Horizon 2020.

assistant: **Abstract**

The X-Pulse project aims at developing innovative active flow control strategies, based on synthetic pulsed jets, also referred as ZNMF, to mitigate the flow separation induced by UHBR powerplant installation on the suction side of the wing when the aircraft is operated at a relatively high angle of attack and low speed. The proposed technological solutions stand at a TRL4 level. Ultimately, they serve the improvement of the aerodynamic performances of the aircraft during these critical take-off, initial climbing and landing flight phases.This project is divided into seven work packages. Six of them deal with technical tasks, the first one being devoted to the coordination. Each work package is subdivided into specific tasks of increasing complexity. Each task falls within the scope of either the ISAE or HIT09. Thus, ISAE and HIT09 offer to join their different skills to elaborate a work-plan based on well-defined responsibilities.The major tasks are summarized below:1. Determination of a high fidelity predictive CFD methodology able to efficiently and accurately predict the flow field around a complex geometry representative of a UHBR powerplant-equipped aircraft for real flight conditions2. Adaptation of this CFD methodology for the high fidelity prediction of the dynamics of ZNMF pulsed jets and of their impact on the previously predicted flow field, in particular in terms of control of the flow separation.3. determination of the optimal ZNMF-based active flow control strategy to implement on the aircraft, able to suppress the flow separation and to improve the aerodynamics performances of the aircraft during take-off, initial climbing and landing. This optimization relies on a multi-objective optimization function, by analyzing the influence of the following paramet
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'CO-CREATIVE IMPROVED UNDERSTANDING AND AWARENESS OF MULTI-HAZARD RISKS FOR DISASTER RESILIENT SOCIETY' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

There is a lack of data, understanding and awareness in Europe and in the world of compound weather and climate extremes. Insufficient governance function also affect the related vulnerability, risk and resilience of people, communities and places. The C2IMPRESS project aims to bring a radical paradigm shift to disaster and hazard research and innovation by moving away from traditional ‘hazard centric’ approach/ framework to a novel ‘place and people’ centred integrated multi-hazard risk and resilient assessment framework. Guided by this framework, the C2IMPRESS project aims to offer an ensemble of innovative revolutionary models, methods, frameworks, tools and technologies that are holistic and robust enough to provide appropriate fine-grained spatio-temporal qualitative and quantitative data, locally appropriate solutions, better prediction with lower uncertainty on risks of single or multiple hazards stemming from extreme weather events like floods, wildfires etc. under different climate change scenarios. Breakthrough innovations from C2IMPRESS project will be System-of-Systems for Multi-Hazard Risk Intelligence Network (SoS4MHRIN) platform (supported by the robust Earth System Dynamic Intelligence (ESDI) and Information Physical Artificial Intelligence (IPAI)), innovative Agent Based Model, polycentric risk governance, multi-actor decision support microservices and a suite of citizen engagement technologies and tools as  well as novel co-design and co-creation approach for socio-technical innovations, knowledge production and validation to empower citizens and society with climate actions for a sustainable transition to a just risk resilient society. With these social and technical innovations -as novel processes and products- the C2IMPRESS project will provide bett
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'BEhavioural ReplicaTion of Human drivers for CCAM' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Europe must seize the opportunities presented by connected, cooperative, and automated mobility (CCAM).  For its deployment, powerful tools enabling the design and analysis of CCAM components, digitally and with a common language between TIERs an OEMs are needed.The lack of a validated - and scientifically based - Driver Behavioural Model (DBM) to cover the aspects of human driving performance is one of the main shortcomings of CCAM development. It allows to understand and test the interaction of CCAM with other cars in a safer and predictable way from a human perspective. DBM is the cornerstone for the development of CCAM components. It will guarantee its digital validation and, if incorporated in the ECUs software, will generate a more human-like response of autonomous vehicles (at any level) and increase its acceptance. The main objective of BERTHA is to develop a scalable and probabilistic DBM based mostly on Bayesian Belief Network (BBN). The DBM will be implemented on an open-source, HUB (repository) to validate technological and practical feasibility of the solution with industry and become a unique approach for the model worldwide scalability. The resulting DBM will be translated into a simulating platform, CARLA, using diverse demos which allows building new driving models in the platform.BERTHA will also include a methodology which, due to the HUB, will share the model to the scientific community to ease its growth.The project includes a set of interrelated demonstrators to show this DBM approach as a reference to design human-like, easily predictable and acceptable behaviour of automated driving functions in mixed traffic scenarios.BERTHA is expected to go from a TRL 2 a TRL 4. The requested EU contribution is €7,981,801. The consortium, 14 entities from 6 co