RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Design of Immune Modulating Dendritic Networks for future treatment of Diabetic Foot Ulcers' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Diabetic foot ulcers (DFU) are one of the most severe and costly long-term diabetic complications, causing a considerable financial burden to patients and healthcare sectors globally. Most commercial wound dressing materials are based on linear natural or synthetic polymers, and they are not capable of treating DFU efficiently. Innovative material design and therapeutic methodologies are critical to provide improved treatments for DFU. Hyperbranched dendritic polymers show advantages of having multiple terminal groups for multivalent interactions, low viscosity, cost-effectiveness and large-scale production in high yield, which are important features in practical biomedical applications. The aim of this proposal is to develop advanced cationic dendritic networks (CDNs) which are designed to eliminate infections and stimulate favorable immune modulation during the DFU healing process. In this context, a library of cationic heterofunctional hyperbranched dendritic-linear-dendritic copolymers (HBDLDs) based on polyethylene glycol (PEG) and 2,2-bismethylol propionic acid (bis-MPA) will be synthesized and hybridized with collagen to fabricate well-defined CDNs to deliver insulin locally for improving DFU treatment. The cations will provide long-term antibacterial activity; collagen, insulin and the dendritic structures and cationic charges are envisioned to provide the immune modulation during DFU healing process. I will study the effects of the CDNs on skin cells at molecular level, and identify functional groups and structures of materials that can actively promote DFU healing. Proof-of concept wound dressings will be designed based on the material properties and gelation mechanism, and methods for large scale production of the optimized hydrogels will be explored. It is p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project '(C)ombinatorial (O)ptimisation for (V)ersatile Applications to (E)merging u(R)ban problems' (COVER) targeting Horizon Europe.

assistant: **Abstract**

In addressing urbanization and sustainable development challenges, this project proposes a collaborative effort to harness the power of combinatorial optimization methods and operations research. Focusing on graph theory applications such as graph coloring and domination, as well as broader optimization techniques like integer programming, our interdisciplinary team seeks to address urban problems across European and Third-Country partners. By integrating expertise from academia, local communities, and industry, we aim to develop tailored solutions that enhance quality of life while promoting sustainable development principles.The project's objectives include identifying local urban challenges, creating theoretical models for optimization, and implementing innovative solutions. Through workshops, trainings, and collaborative research, we will engage stakeholders to define and prioritize urban problems, laying the groundwork for practical applications of combinatorial optimization techniques. Key initiatives include exploring the “15-minute city” concept to improve accessibility and mobility, proposing optimization models for post-disaster management, optimizing the placement of semi-mobile clinics for healthcare accessibility, and developing solutions for public transport networks.The project's innovative program encompasses various activities, including problem definition, theoretical modeling, empirical research, and knowledge exchange. Through a structured work plan, we aim to foster collaboration, knowledge sharing, and capacity building among project partners. By leveraging the expertise and diversity of our international consortium, we seek to create sustainable solutions with lasting impacts on urban communities beyond the project duration.Overall, this project p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Farming economically, a new path to sustainable rural development in Galicia, Spain', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

Research on Galician agriculture so far emphasised the need of scale enlargement and modernisation. As a result, social and environmental aspects of development were ignored. This research aims at supplying an alternative approach to rural development applying a tri-dimensional (ecological, economic and social) concept of sustainability within a regional context. It integrates multiple disciplines - ecological economics, agroecology and rural sociology- in order to assess the sustainability of different sty les of farming and the potentials of farming economically. Farming economically is a promising farming style as it is based on low-external-input agriculture that fits well into the concept of sustainable development.Gender-specific aspects are taken into account as women's and men's possibility to profit from rural development differs. The research project will result in the development of methodological tools that allow for a multidisciplinary analysis of agriculture and rural development. Moreover, the research project will construct a multidisciplinary theoretical framework that combines economic, natural and social sciences, focusing on the so far separately developed ecological, social and economic domains of sustainability. Taking into account that t his project does empirical research in an Objective 1 region (Galicia), the research activities can be of high importance for other disadvantaged regions in Southern, Central and Eastern Europe.It delivers information that policymakers need for developing and implementing region-specific policy measures and are capable of efficiently promoting lasting local development. With the 6th framework this project as an EIF Marie Curie fellowship advances the knowledge and expertise of the candidate on matters of European
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Synthetic Jet flow Control CFD and Characterization'.

assistant: **Innovation**

The objective of the project is is to develop scale models for the Synthetic Jet Actuator (SJA), that shall be used to enable the design of next generation SJA’s, compared to state of the art. The development of this scale model is intented for improvement of performance predictions, and modelling accuracy of SJA actuators, for future applications. A demonstration rationale is therefore targeted, in order to enable accurate theoretical performance estimations, for given actuator configurations, calculated from geometrical input parameters, and transducer elements parameters.   In order to achieve such an objective, the project activities will focus first on analyses and tests of existing SJA’s designs, provided by the topic manager, in order to derive accurate numerical models, and achieve lessons learings, before designing, manufacturing, and testing of a third scale model.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'ArcInTex ETN' (2014-2020).

assistant: **Innovation**

A fundamental challenge in design research today is to define the design programs that suggest how we can turn our days scientific knowledge and technical development into design for new forms of living that will provide foundations for a more sustainable way of life. Through a cross-disciplinary and cross-national network in architecture, textiles and interaction design the consortium will build and train a new research community to take on this challenge in practice based design research from a broader perspective, incollaboration between academia and the private sector, combining areas of design where Europe by tradition have a very strong position. The proposed ArcInTex ETN aims to strengthen the foundations of design for new forms of more sustainable ways of living by connecting architecture, textiles and interaction design in a training network for Early stage researchers. Deepening connections between textile,  architectural and interaction design will open up for new reflective foundations of the design for living in an age of technological innovations, designing for adaptive and responsive environments connecting the scales of the body, the interior and the building. By a combination of in depth specialization, collaborative project work training and company internship, the ESRs of the network will form a highly trained avant-garde ready to take on fundamental challenges both in academia and in the private sector building their work practice on new ideas of material thinking and design thinking with emphasis on sensitive design expressions for reflective living. By strong focus on practice based design research the ETN will contribute to further establish design research at a level similar to that of engineering science in areas of special importance for the de
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Surface improvement of metal implants: new preparation methods and new materials' (SIMI) under Fifth Framework.

assistant: **Objectives**

Transmucosal metal implants are mainly employed in orthopedic and dental surgery. The economical impact of these treatments will largely increase due to the ageing of European people. The main objective is to develop new surface treatments on titanium implants able to trigger and to control cell differentiation with the ability of different biological functions to be fulfilled simultaneously in different loci of the implant. Two different and complementary ways are proposed to reach these goals: (i)titanium surfaces modifications based on nanometric multilayered polyelectrolyte films; (ii)improvement of pulsed laser deposition with highly bioactive calcium phosphates.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Realistic supercomputer simulations for gravitational wave asteroseismology' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

With several gravitational wave (GW) detectors already operating, the first signal detection is anticipated shortly. The challenge for data analysis is to extract signals from ambient noise, thus predictions of expected waveforms are essential.We will per form the up-to-date most realistic numerical simulations of rotational stellar core collapse to a proto-neutron star (PNS) in general relativity. We will use a sophisticated equation of state, include a modern approximation scheme for neutrino effects, and take latest results from stellar evolution as initial models.We will employ a fast and stable novel 3d evolution code, enabling us to surmount severe previous limitations, like symmetry restrictions, a crude matter model, Newtonian gravity, or numerical instabilities.We will particularly focus on analyzing frequencies and energy content of various pulsations in the nascent PNS, as these are a source of potentially detectable GWs. A new formulation of the spacetime equations will enable us to extract GWs directly from the spacetime metric.Our results will provide essential input for the emerging field of GW asteroseismology (GWA). GWA is concerned with interpreting measured signals from detectors and constraining still uncertain properties of matter in compact stars predicted by nuclear physics. Our project will extend GWA to include the significant effects of rotation and high temperatures.In addition, we will investigate other promising phenomena for GW emission in rotating PNSs such as the appearance of instabilities. If confirmed, these may prove to be even more important for GW astronomy than direct excitation of pulsations during core bounce.As this project will use methods and resources of supercomputing, it will support and benefit from EU RTD activities on 'G
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Stray Light Suppression Coating for Additively Manufactured Aerospace Components' (SolCoat) under Horizon 2020.

assistant: **Objectives**

Thermo-optical coatings with high optical absorptance and high thermal emittance are a critical technology for a range of different space applications, including stray light suppression, and also passive thermal control of the internal surfaces of satellites. Development of new space coatings with high thermal emittance have also been highlighted as important for accurate absolute temperature calibration (Section 4.9.2 N28b of the European Commision/ESA/EDA Draft Critical Space Technologies for European Strategic Non-Dependence).In the past few years, the use of additive manufacturing for satellite components (both structural and functional elements) has increased rapidly. This has fuelled a shift towards topologically optimised hardware. Although topological optimisation reduces component mass, it typically results in very complex geometries, which are difficult to coat by conventional means.The applicant company is seeking to develop a thermo-optical coating for space applications with suitable optical properties for use as a stray light suppression coating, which is conducive to deposition on complex shaped geometries produced by additive manufacture (AM). Specifically, the coating would require high optical absorptance (≥ 0.96) and high thermal emittance (≥ 0.90), along with suitable rheological properties. A coating with these optical properties could additionally be used for coating the internal surfaces of satellites in order to maximise heat dissipation from high power density payloads.


**Keywords:** thermo-optical, coating, stray light, protection, satellites, earth observation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Utilising the upgraded T2K near detector and developing water-based liquid scintillator technology towards a CP violation measurement in neutrinos' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

The dominance of matter over antimatter in our universe is an unresolved question in our Standard Model of particle physics. Measuring Charge-Parity violation in neutrino oscillations at long-baseline neutrino experiments is crucial for understanding this phenomenon. The T2K experiment, which is currently operational, and its successor HyperKamiokande, beginning in 2027, are the most sensitive probes for measuring CP violation in neutrinos, and early hints of maximal violation have been published by T2K. There is a discovery potential with the data that will be taken in T2K over the course of this fellowship period if CP violation is indeed maximal, or with precision measurements to be performed using high statistics at HyperK. To achieve this in T2K its recently upgraded near detector, ND280, must be fully utilised, and for the high-statistics precision era in HyperK, further upgrades to ND280 will be needed. This project aims to characterise and maximise the performance of the upgraded ND280, using the state of the art Super Fine Grain detector and high-angle Time Projection Chambers that were installed with the final goal of reducing systematic uncertainties in neutrino measurements from ~6% to ~4%. The new detectors will be used to perform a measurement of the electron-neutrino cross-section to reduce this as a large systematic uncertainty contribution in CP violation measurements. This measurement will maximise CPV discovery potential in T2K, while the characterisation and methodology will be critical in HyperK to achieve a precision measurement faster. To reach systematic uncertainties below 3% in HyperK, research into using a large scale water-based liquid scintillator detector in ND280 will be undertaken, including building and characterising prototypes to then
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Constructing and Representing the Past in the Ottoman Royal Atelier: A Synthetic Treatment of Sixteenth-Century Historiography and Illustrated Manuscript Production', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

This project is a synthetic treatment of sixteenth-century Ottoman historiography and the production of illustrated manuscripts in the Ottoman royal atelier. It focuses on the drafting and editing stages of production, and the relations between patrons, historians and artists.Two sets of manuscripts will be examined in detail: (1) The corpus of the historian Nasuh-i Matraki from the 1520s-1550s and (2) manuscripts containing the narratives of Caucasian campaigns written in the 1580s and 1590s. In each case, questions of intended messages and readership/audience will be addressed with careful consideration of the final illustrated products against their drafts and the annotations on them. The production of illustrated histories will be further examined in social context with the help of archival documents.The project proposal includes extensive training of the researcher in handling Ottoman illustrated manuscripts and analyzing them in terms of physical qualities (paper, binding, ink etc) and artistic style.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Small RNA-guided complex machinery for epigenetic silencing' under Seventh Framework.

assistant: **Concept**

Transposons are parasitic DNA elements that when activated can insert into new genomic locations, leading to genomeinstability. Animal germlines express a special class of small RNAs called piwi-interacting RNAs (piRNAs) which areimplicated in transposon silencing. In mammals, they are believed to promote DNA methylation of transposon-rich genomicregions. Mechanisms of piRNA biogenesis and function are only beginning to be understood. Sequence analysis of piRNAsfrom a variety of organisms has given rise to working models for piRNA biogenesis and how piRNAs might act as guidesfor nuclear silencing complexes. However, key components of the pathway, especially those for biogenesis and function,remain to be discovered. Our aim is to identify and characterize new components using a combination of biochemistry, mousegenetics and small RNA bioinformatics. The regulatory potential of posttranslational modification of piwi proteins and theirrecognition by tudor proteins will be examined. Mouse mutants will be used to study the in vivo role of catalytic activity ofpiwi proteins in piRNA biogenesis and identify putative targets by transcriptomics approaches. Integrated biochemical anddeep-sequencing methods will be applied to understand how small RNAs might guide nulcear silencing machinery to targetlocations. Finally, in a field that is dependent on model organisms, we propose to develop a cell culture system to study thepiRNA pathway and carry out a high-throughput functional RNAi screen for component discovery. This proposal aims touse interdisciplinary approaches in uncovering the biochemical framework in which germline small RNAs function to protecteukaryotic genomes.