RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Modeling Stellar Collapse and Explosion: Evolving Progenitor Stars to Supernova Remnants' to be submitted under Seventh Framework.

assistant: **Abstract**

This project intends to make groundbreaking progress towards the solution of one of the most pestering and long-standing riddles of stellar astrophysics, namely the question how massive stars explode as supernovae (SNe).State-of-the-art simulations in two dimensions (2D) now yield neutrino-powered (through underenergetic) explosions for a growing variety of progenitors and thus support the delayed neutrino-heating mechanism. However, sophisticated, fully self-consistent, 3D simulations are still lacking, the spherical symmetry of the progenitor star models is becoming a serious handicap, and better exploitation of observational constraints of the SN mechanism is urgently needed.For these reasons we plan a novel, comprehensive modeling approach, in which 3D hydrodynamics including all relevant microphysics will not only be employed for the launch phase of the SN blast wave by neutrino-energy deposition. Different from previous initiatives, 3D hydrodynamics will also be applied to the final stages of convective shell burning in the progenitor core before collapse in order to derive --for the first time-- self-consistent, multidimensional progenitor data for adopting them as initial conditions in the SN modeling. Moreover, the 3D explosion simulations will be continued consistently through the long-time evolution of the SN outburst into the gaseous remnant phase. This challenging approach promises fundamentally new insights into the processes that trigger and shape SN explosions and will revise our understanding of how SNe depend on the properties of their progenitor stars. Moreover, heading for a direct comparison of the derived theoretical models with nearby young SN remnants like Crab, Cassiopeia A, and SN 1987A, whose 3D morphology and composition are currently unfolde
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Aging vision: Crystallins, visual acuity and cataract' (1994-1998) under Fourth Framework.

assistant: **Objectives**

Objectives:To identify the crystallin protein interaction sites involved in the aggregation that leads to cataract with the aim of designing small molecules or mimetics that block aggregation.One of the hallmarks of aging is disease due cellular instability, the result of damage to macromolecular components. The most common of such diseases is cataract. Cataract is the most frequent cause of blindness in man and occurs inevitably with age, about 50% of the people 70 years of age suffer from significant loss of vision due to cataract. The high incidence of cataract results from one of the unusual properties of the lens: its mature fibre cells are incapable of macromolecular synthesis and damaged components cannot be replaced. For transparency, the lens depends on the short range interaction of its highly abundant structural proteins, making the lens particularly sensitive to protein misassembly. The built-in chaperone of the lens, alpha-crystallin, prevents aggregation of unfolding crystallins. The present theory is that cataract is irreversibly initiated, once the chaperone capacity of alpha-crystallin is exhausted. It is the objective of this RTD-project to determine the interaction sites through which the unfolding bta- and lacet-crystallins aggregate. The definition of such sites then allows the design of compounds that interact with these sites to prevent misassembly and thereby prevent or delay cataract.To that end a combination of molecular biological, biochemical, cell biological and biophysical techniques will be used to determine- the chaperone capacity of alpha-crystallin towards other human crystallins;- the stability of the various human crystallins and the effect of post-translational modification (clipping, oxidation) there on the interaction between huma
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Total synthesis of martinelline and martinellic acid', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Research objectives and content The objectives of the present proposal are the total synthesis of martinelline and martinellic acid, two alkaloids with a triciclic core of pyrrolo(3,2-c)quinolone system that had not been reported previously in any natural product. Both alkaloids were isolated in 1995 from the root of Martinella iquitosensis for Merck laboratory and show bradykinin B 1 and B2 receptor antagonist activity in studies made for a group at Merck. This year the group of Dr. Jones have started the synthesis of both alkaloids and recently has published a short, high-yielding synthesis of the tricyclic pyrroliquinoline core of martinelline. The key step of this synthesis was the radical cyclisation of an aryl radical onto a pyrrole ring. The present proposal calls for extending this radical cyclisation into a total synthesis of these interesting natural products, firstly in a racemic way and secondly in a enantiopure form. The successful completion of this project will represent an important step forward in the use of aryl radical chemistry in natural products synthesis and would open the way to the preparation of analogues of martinelline with enhanced biological activity. Training content (objective, benefit and expected impact) This project will provide excellent training in modern synthetic organic chemistry. It involves radical chemistry, organometallic chemistry and modern heterocyclic chemistry all carried out against the challenge of the synthesis of an unusual and interesting natural product. Chemist with expertise and training in this area are much sought after by the pharmaceutical and agrochemical industries. Links with industry / industrial relevance (22) The synthesis of martinelline and some of their analogues will be of significant interest to pha
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'When bad things happen to good brands. On how to deal with product-harm crisis'.

assistant: **Concept**

Product-harm crises are prevalent in today’s marketplace. Notable examples include contaminated coca-cola in several European countries and salmonella poisoning in Brinta’s breakfast porridge. These crises can have a tremendous impact on society as well as on the affected companies. Moreover, the number of product recalls is on the rise both in the US and Europe. Not surprisingly, the European Union has realised the importance of product-harm crises to public safety and has fairly recently installed information sharing systems to facilitate the rapid diffusion of product safety information amongst its member countries. Although information on hazardous products now fairly quickly reaches the consumers, still little is known about the influence of these negative events on consumer purchases.   In contrast to previous literature on this topic that mainly focused on one particular crisis event, this research proposal consists of the systematic analysis of a unique database, containing purchase data surrounding a large sample of product-harm crises in three European countries. By systematically analyzing this large sample of crisis events, we will be able to create generalizable knowledge on consumer reactions to these negative events, while accounting for the potential moderating impact of different consumer, category and crisis characteristics such as loyalty, the length of the recall period and the amount of negative news. Not only will this research thus lead to an advancement of science on the topic of product-harm crises, it will also allow us to make reliable recommendations for companies on how to effectively deal with a crisis event.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'DESIGN AND MANUFACTURING OF HEELS FOR SHOES, BY COMPUTER' (DITACOR) under Fourth Framework.

assistant: **Objectives**

This project integrates elements of validation and technology transfer within the footwear industry. Footwear is an important industry in a large number of European countries, particularly France, Italy, Spain , Portugal and the UK. The project team included organisations from most of these countries allowing the transfer of knowledge and experience and the practical demonstration of the technology. It was perhaps surprising that there were no partners from Italy which is by far the largest shoe manufacturer, with a very high proportion of women's shoe manufacturers (important for heel design) and a high number of shoe designers.DITACOR is a specific design software for heels and top piece moulds for footwear. Its ultimate aim is to replace the craft form of the work with a new procedure which speeds up the launch processes and allows the systematisation of processes currently carried out on a manual basis.The overall objectives and aims of the project were:- To promote the use of an innovating design-manufacturing tool in the footwear industry in which craft manufacturing procedures are still used (heels and top-pieces), with the aim of improving its competitive position.- To adapt the results of a previous R&D project to the methods used in local industry, so that the working environment is as friendly as possible.- To evaluate the change that the introduction of the new procedure will bring about in the current production systems, especially from the point of view of the human resources and their qualification. Improving the re-qualification of human resources and consolidating the employment in SMEs.The system for using CAD linked to NC production machinery and /or soft prototyping equipment had not been used in the design of heels (for women's shoes). The tradition
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'European Friedreich's Ataxia Consortium for Translational Studies', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

EFACTS (the European Friedreich’s Ataxia Consortium for Translational Studies) assembles a body of expertise to adopt a translational research strategy for the rare autosomal recessive neurological disease, Friedreich’s ataxia (FRDA). FRDA is a severely debilitating disease that leads to loss of the ability to walk and dependency for all activities. Some patients have cardiomyopathy that can cause premature death, visual and auditory loss, kyphoscoliosis, pes cavus, diabetes. Onset is usually in childhood, but it may vary from infancy to adulthood. FRDA involves child health and ageing aspects. FRDA affected individuals and clinical specialists are dispersed. This is a hindrance for patients to receive the care they need, and for clinicians and researchers to make progress. EFACTS has been created to move past this limitation. EFACTS strongly believes that, 12 years after European researchers discovered the FRDA gene, frataxin, when new treatments for FRDA are being developed, the time is ripe to invest in FRDA research in a concerted Europe-wide fashion. EFACTS gathers the critical mass of researchers and clinicians to exploit the patient base, research reagents and knowledge for progress. This comes when IT can act as a crucial support for collaborative work in collecting patient data and material, making it available to leading researchers for advanced analysis, research and drug development. This project proposal has the following scientific and technological objectives: 1. Comprehensively populate a European FRDA database, linked to a bio bank; 2. Define a panel of clinical assessment tools; 3. Build on the knowledge base of frataxin structure and function; 4. Build on the knowledge base of the pathogenic cascade; 5. Build on the knowledge base of epigenetic mechan
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Asean application for the Opet Network' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Objectives: Providing a focal point in the ASEAN region for European collaboration with similar intergovernmental or regional organisation initiatives. Dissemination of documentation and information of RUE and RES technologies in the ASEAN region including information on EU energy policy and technology issues. Assessing RES and RUE potentials with focus on Malaysia and Thailand and encouraging the ASEAN energy market actors to utilise clean and efficient energy. Co-ordinating, promoting and assisting Framework Programme non nuclear energy RTD technology developers and suppliers in identifying new ASEAN markets.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Uncertainty and Industrial Knowledge Management: A Dynamic Capability Perspective', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

The future role of European Manufacturing Industry has been extensively debated among policy makers,practitioners and researchers.This debate highlights the importance of researching the management of industrial knowledge in a holistic manner.Knowledge on this topic however is largely fragmented into different research streams that lack integration and coherence.Previous research also lacks a multidisciplinary perspective and therefore falls short of addressing the multifaceted phenomena that occur in indus trial contexts.This project aims to integrate the deferent strands of theory as well as focusing on new challenges.The knowledge-based theory of the firm will be used as a foundation for the framework,around which insights from strategic management,organis ational cognition and innovation management will be integrated.This integrative framework will be further refined and extended through the adoption of in-depth empirical research within a number of manufacturing companies in order to develop an explanatory process theory for managing industrial knowledge under uncertainty.This research will contribute to scientific knowledge by studying the reciprocal interaction between cognitive mechanisms and industrial knowledge development.The project is innovative in that it takes a longitudinal perspective and will adopt multilevel theorizing that will analytically link the strategic level with the practice of innovation and change.The project aims to increase the scientific competency of an experienced researcher by complementing his industrial experience and operations strategy research expertise with knowledge of organisational cognition.Leeds University is an appropriate institution to provide this scientific guidance and training.Its scientific excellence in inter disci
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Japan, Religious Education And Critical inTerculturalism. Approaches from the Study of Religions and Didactics.' (JREACT).

assistant: **Innovation**

The JREACT Project wants to provide a non-confessional model for teaching about religions in schools, i.e. Religious Education (RE), that eschews ethnocentrism and promotes critically self-reflection, diversity and inclusiveness. It does so by engaging the case-study of RE in Japan from the point of view of the academic Study of Religion (SoR).In the last 20 years debates and developments on RE and Intercultural/Citizenship Education (ICE) have increasingly intersected, especially in Europe. However, the SoR has since long criticized the modern, Christian and ethnocentric biases inherent in the concept of “religion”, thus highlighting an intrinsic intercultural weaknesses in RE. Nonetheless, International/European research aimed at the creation of SoR-based RE didactics still lacks a thorough engagement with non-western contexts. This hinders the creation of a full-fledged intercultural and inclusive RE.JREACT want thus to improve European SoR-based RE through a comparative analysis with the Japanese case. The reasons to choose Japan are its peculiar religious situation (which often eludes Eurocentric views on religions), its long scientific tradition (for and non-European country) in the modern study of religion, and an ongoing debate on the role of  RE in schools. It will contextually compare Japanese and European SoR-based RE theories and methods, looking for unnoticed biases, mutually reinforcing points, uncharted areas and contrasting points. From this it will elaborate innovative concepts and methods for RE and articulate them into guidelines.Its interdisciplinary approach combines SoR, Didactics, Anthropology of Education and ICE. JREACT will establish my position as an expert in intersecting fields: comparative RE; society & religion in contemporary Japan, theor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Does Public Funding Matter? The Effect of State Subsidies to Political Parties on Political Corruption' (PFCorr).

assistant: **Concept**

The chief normative assumption underpinning the provision of public funding to political parties holds that state funding aims to diminish their propensity to engage in corruption-prone exchanges through financing from illicit sources. Yet, the empirical testing of this supposition has received little attention from a comparative perspective. At best, existing comparative studies relied on very crude measures to estimate the effect of subsidies on political corruption. This project will partially address this gap by using better measures of both explanatory and explained variables. Unlike existing research, which employs either composite indexes of various financing regulations or binary measures of public funding (i.e. the lack vs. the availability of state subsidies) to estimate the effect of state subsidies on corruption, this project embarks on a different path. It will use hard data on state funding provided to political parties, which will be standardized to make it comparable cross-nationally and over time. It will also employ alternative measures of political corruption (e.g. experience-based, public perception, text analysis), which do not rely exclusively on expert-based evaluations.  The analysis will be conducted using an original data-set on the de facto level of state funding, operationalised as the annual average of direct budgetary subventions per voter at the national level for 27 post-communist regimes between 1990/1991 until 2018. To estimate the direction and strength of the relationship between public funding and political corruption, as well as to explain the underlying causal mechanism, according to which a higher level of state subsidies is expected to diminish political corruption, this research will employ a mixed-method research design. It wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Development and Testing of Practical Guidelines for the Assessment of Environmental and Resource Costs and Benefits in the WFD'.

assistant: **Objectives**

The concept of environmental and resource costs plays a central role in the economic analysis of the European Water Framework Directive (WFD). However, there are no methodological guidelines regarding their practical assessment. The main objective of this project is to develop and test such practical and policy relevant guidelines. This will be achieved through the development of standard procedures and a protocol for good practice in decision appraisal for the WFD. These guidelines will then be tested via a series of case studies of selected, representative European river basins.Outcomes of these case studies will be used in two ways. First, this information will be used to refine the guidelines for good practice in WFD decision appraisal. Second, the common design of case studies will permit investigation of techniques for transferring economic values of environmental and resource costs and benefits from water body level to national and international river basin level and vice versa. As part of this exercise we will also investigate the use of geographical information systems (GIS) to synthesise data from the case studies with available physical environment and census data so as to generate a Europe-wide map of expected benefits of improved water quality due to WFD implementation.The proposed project is highly policy focussed, being driven from the outset by the direct involvement of a Europe-wide Steering Committee of policy-makers and other stakeholders directly involved in the implementation of the WFD.