RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Salan Ti(IV) Complexes as Novel Anti-Cancer Chemotherapeutics' (IV) under Seventh Framework.

assistant: **Objectives**

Cisplatin is a platinum-based complex used widely as a chemotherapeutic drug. However, due to its limitations, including narrow activity range and severe side effects, other transition metal complexes are investigated as antitumorur agents. Titanium complexes that previously reached clinical trials showed fair activity, and were mainly limited by rapid decomposition in water, within minutes. Titanium complexes of diamino bis(phenolato) (""salan"") ligands studied in our laboratory under the ERC grant demonstrate extremely high stability for up to weeks in water solutions. Importantly, they have shown great potency as anti-tumour agents towards a number of cells in vitro. Their activity exceeds that of cisplatin by up to two orders of magnitude. In particular, halogenated compounds at specific positions demonstrate a combination of exceptional hydrolytic stability and particularly high cytotoxicity, and are covered in a patent application. In addition, minor effect on regular cells was observed. As the titanium has been previously shown based on in vivo testing to be significantly less toxic than platinum, (and is commonly found in food and cosmetics), several pharmaceutical companies expressed interest in our compounds. However, in vivo activity and some mechanistic insights (required for FDA approval) are fundamental for allowing commercialization. Therefore, we propose to conduct a series of experiments that will bring this research to a more ""mature"" level suitable to be undertaken by pharmaceutical companies. These include in vivo testing on mice to establish safety and activity towards different cells and by different administration techniques, including IV. Additionally, as solubility is an issue, different formulations will be assessed. Basic mechanistic studie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Cognitive Electronics' to be submitted under Horizon 2020.

assistant: **Abstract**

Tackling the various societal, economic and environmental challenges faced by the EU can be supported by ICT-based solutions such as Wireless Sensor Networks, RFID, Internet of Things… R&D in so-called smart embedded and energy efficient electronics is increasingly important so that such solutions perform adequately, reliably and securely, adapt to changing conditions, and be energetically less visible as their number grows; i.e., future electronics should have cognitive functions deeply embedded into them.Establishing an ERA Chair at T.J. Seebeck Department of Electronics, Tallinn University of Technology, will help it keeping abreast with the above research specialization by increasing its research capacity in cognitive electronics related topics such as new architectures, methods and tools for energy-efficient sensor signal processing, new sensor technologies with improved yield, and efficient communication techniques for autonomous systems and RFID solutions. Promising applications include pervasive ambient medical/health monitoring, inspection of the structural health of materials and constructs, smart transportation and smart energy distribution. The main task of the ERA Chair will be to breathe new competences, federate resources, and increase the integration of existing research activities by building a coherent research framework in the department. The increased research capacity initiated by the ERA Chair will not only result in significant contributions to the above scientific topics, but will also increase the department visibility at the European and international levels. While much attention will be paid to cooperation with the industry, the key target is coordination of the research in the area of cognitive electronics, including with other academic and t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Mrc human movement and balance unit'.

assistant: **Concept**

Description:With effect from 31.3.2001 the Medical Research Council Human Movement and Balance Unit ceased to exist and the Neuro-Otology Section of that group moved its staff and large scale facilities to new premises at Imperial College of Science, Technology and Medicine, London. The new Balance and Spatial Orientation Group continues to be funded by the Medical Research Council under the leadership of Professor Adolfo Bronstein.The group's remit is to conduct research into human movement and balance in the widest sense of the term including the initiation and execution of movement and the control of movement and balance by visual, vestibular, and proprioceptive signals. Recent additions include research programmes and technical facilities for the study of the autonomic nervous system component in movement and disorientation. The group has special emphasis on understanding disorders which arise from neurological, oto-ophthalmological, and psychological disease and conducts a substantial part of its research on patients. The group's manpower comprises permanent clinically trained scientists and non-clinical scientists supported by technical and administrative staff.Its uniqueness lies in the fact that the group possess many heavy duty, whole body, motion devices for the assessment of posture and balance, and that these facilities are located within a neurological environment.Application:Applications for access can be by post, or email at our new address: Academic Department of Neuro-Otology, Division of Neuroscience and Psychological Medicine, Imperial College Faculty of Medicine, Charing Cross Hospital, Fulham Palace Road, London W6 8RF, UK Tel: +44-208-8467285Fax: +44-208-8467577Email: neuro-otology@ic.ac.ukInternet:http://www.med.ic.ac.uk/divisions/template_divisio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'All Aqueous, continuous, Solid-Liquid SYNergisticEXTRACTion of rare earth elements' (SYNEXTRACT) targeting Horizon 2020.

assistant: **Abstract**

It is a matter of strategic independence for Europe to urgently find processes taking into account environmental and economic issues, when mining and recycling rare earth elements (REE). As of 2015, only 1% of used REE were recycled in the EU and 80% of the mining operations were performed in China, hence representing a major Sword of Damoclès for the rest of the world’s economy. With SYNEXTRACT, we propose to leverage on discoveries made (and patented) within ERC-Adv REE-CYCLE, related to new extracting liquid-liquid process. Hence, SYNEXTRACT will try to implement these discoveries in a Solid-liquid extraction process based on Simulated Moving Bed Chromatography. Such process would complement nicely the liquid-liquid one. Indeed, in case of success, it would not only represent a new approach in chromatography, but it would also enable highly flexible purification  processes for REEs containing waste streams, that can easily be adapted to various waste stream lixiviates. Due to the high selectivity, it could even be applied to low REE concentration lixiviates. The process flexibility is one of the main bottleneck to enable their recycling as the research and development cost currently necessary to adapt current liquid-liquid extraction processes prohibits it. It should also be mentioned that SYNEXTRACT process would be all aqueous, therefore avoid the use of organic solvent and would drastically reduce process wastes and running costs.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'REINFORCING FAMILY BONDING: INTERNATIONAL TRAINING OF BEHAVIOURAL AND AFFECTIVE EVIDENCE BASED INTERVENTION AGAINST EARLY ADOLESCENTS RISK BEHAVIORS' under Seventh Framework.

assistant: **Concept**

The present proposal is aimed at increasing the expertise of the researcher in the field of prevention against drug use and problem behaviours in adolescence. For this purpose, the researcher is supposed to go to the Orebro (Sweden) University to learn about two kinds of prevention programs against problem behaviours in adolescence. Both of them are tested to be effective in preventing youth’s internalizing and externalizing problems. They are focused on family, even though they are based on different theoretical principles. As they are tested prevalently in North Europe and US countries, this proposal will allow to transfer this knowledge to the South Europe and find out what are the best way to implement them in different countries. Indeed, one of the goal is to learn about those programs in order to implement them in the origin country of the researcher (Italy). Specifically, the training in the host country will include a phase of learning and a phase of supervision of the results obtained in Italy. In the first phase, the researcher will be taught about the content of the programs. Moreover, it will be discussed together with Orebro staff the best way to implement such programs in a different country such as Italy. In the second phase, the researcher will be taught about new techniques to analyse data. This knowledge will allow to evaluate what program is more effective in decreasing problem behaviors. Particularly, it will be possible to know what components of these programs are more effective. The goal is to find a way to integrate these kinds of programs in order to augment their effectiveness. This proposal is of relevance for Europe as it will allow to experiment new kinds of prevention programs in European areas that are not reached by this knowledge. Moreov
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Quantum-mechanical simulations for the nanoscale'.

assistant: **Concept**

A leading scientific software company and a renowned university research group will jointly develop new, quantum-theory based methods and concepts to allow quantum-mechanical computer simulations of systems in the 100,000 atoms range, and apply them to study challenging applications. As a result, a new chapter of atomistic computer simulation will be opened, as quantum-mechanical simulations will become feasible to study systems and processes in nanotechnology, biochemistry, supramolecular and inorganic chemistry, and in particular interfaces between these domains. SCM N.V. is an SME founded in 1998 as a spin-off of the VU University in Amsterdam, and has developed since then into one of the market leaders for quantum chemical software. The Computational Materials Science group of Prof. Heine at Jacobs University has a long experience in nanomolecular sciences, including organic and inorganic nanomaterials, spectroscopy, dynamic effects etc. The project is based on recent developments of the Heine group, which rely on an approximate DFT (A-DFT) method which is applicable throughout the periodic table, and which is capable of dealing with systems in the 100,000 atoms range. For highly accurate simulations and spectroscopy, a related hybrid method between DFT and A-DFT (AxDFT) will be developed. The methods will be brought through secondments to SCM where they will be implemented into its software product ADF and brought into the market. The resulting software will be used for challenging applications in the fields of nanoelectromechanics, supramolecular and inorganic chemistry, and nanoporous materials. With this initiative ADF will become significantly more competitive and SCM will strengthen its position on the market of quantum-theory based computer software, which is
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Multiple Representations-Multiple Resolutions'.

assistant: **Innovation**

The project aims at the specification of a new data management technology explicitly supporting multiple representations and multiple resolutions of spatio-temporal data. This includes the definition of an appropriate data model, a query language, and associated data services. The multi-representation requirements to be addressed by the project will be based on the analysis of two existing applications, a cartographic application and a risk management application. The proposed solutions will be materialised by the development of a software layer (middleware) on top of an existing GIS/DBMS that will be tested and validated against the applications. Objectives:Successful information management implies the ability to design accurate representations of the real world of interest to targeted applications. Current systems do not provide representation schemes supporting the diversity of user needs. In the context of interoperability, as in Web access to heterogeneous data sources, they cannot properly integrate the diversity of stored representations. The objective of this proposal is to enhance GIS (or DBMS) functionality so that, relying on more flexible representation schemes, users may easily manage information using multiple representations. The added functionality will support multiple coexisting representations of the same real-word phenomena (semantic flexibility), including representations of geographic data at multiple resolutions (cartographic flexibility). This will in particular make possible a semantically meaningful management of multi-scale, integrated, and temporal geo-databasesWork description:While MurMur aims at developing a new generic scheme for multiple representations in data modelling, it focuses in particular on the needs related to geographic data m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The development of a social, industrial and economic method for the disposal and recycling of truck and car scrap tyres' under Fourth Framework.

assistant: **Concept**

THE SCIENTIFIC & TECHNICAL OBJECTIVES OF THIS RESEARCH PROPOSAL CONCERN THE INNOVATIVE HOLISTIC APPROACH TO THE PROBLEM IN THE DISPOSAL AND RECYCLING OF TRUCK AND CAR SCRAP TYRES. THE RESEARCH IS REQUIRED TO ASSESS SHEAROGRAPHY TECHNOLOGY TO INCREASE THE RETREADING OF EXTENDIBLE LIFE CASINGS, IMPROVING THE DISMEMBERING AND RECYCLING OF SCRAP CASINGS, DEVELOP BONDING POLYMERS TO PROVIDE AN IMPROVED MEANS OF INJECTION MOULDING RECOVERED RUBBER GRANULATE AND ASSESS THE FEASIBILITY OF USING PRE-CURED RUBBER CRUMB IN THE PRODUCTION OF RUN FLAT AGRICULTURAL TYRES, FOR-WHICH A EUROPEAN PATENT HAS BEEN GRANTED
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Land-Climate Interactions: Constraints for Droughts and Heatwaves in a Changing Climate' (DROUGHT-HEAT), addressing dissemination and exploitation.

assistant: **Impact**

Land-climate interactions mediated through soil moisture and vegetation play a critical role in the climate system, in particular for the occurrence of extreme events such as droughts and heatwaves. They are, however, poorly constrained in current Earth System Models (ESMs), leading to large uncertainties in climate projections. These uncertainties affect the quality and accuracy of projections of temperature, water availability, and carbon concentrations, as well as that of projected impacts on agriculture, ecosystems, and health.In the past years, in-situ and remote sensing-based datasets of soil moisture, evapotranspiration, and energy and carbon fluxes have become increasingly available, providing untapped potential for reducing associated uncertainties in current climate models. The DROUGHT-HEAT project aims at innovatively exploiting these new information sources in order to 1) derive observations-based diagnostics to quantify and isolate the role of land-climate interactions in past extreme events (""Diagnostic Atlas""), 2) evaluate and improve current ESMs and constrain climate-change projections using the derived diagnostics, and 3) apply the newly gained knowledge to frontier developments in the attribution of climate extremes to land processes and their mitigation through ""land geoengineering"".The DROUGHT-HEAT project integrates the newest land observational datasets with the latest stream of ESMs. Novel methodologies will be applied to extract functional relationships from the data, and identify key gaps in the ESMs' representation of underlying processes. These will build on physically-based relationships, machine learning tools, and model calibration. In addition, they will encompass the mapping and merging of derived diagnostics in space and time to red
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Modeling the past climates of planet Mars to understand its geology, its habitability and its evolution' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

Over the past decades, the robotic exploration of the planet Mars has produced a wealth of geological observations. They show that Mars has not always been the desert planet of today. It has seen eras conducive to rivers and lakes, ice ages, and even periods with a collapsed atmosphere. These different epochs are the reason why Mars remains the objective of space agencies, as they evoke the possibility of past habitability and spectacular climate changes.Yet, in spite of all the data, the climatic processes that have shaped Mars’ surface through time remain largely unknown. What happened on Mars? Was the Red Planet suitable for life? What explains its evolution?The objective of this project is to develop numerical models to simulate the past environments of Mars.A completely new “Mars Evolution Model” will be created by asynchronously coupling hydrology, glacial flows and ground ice models with a new generation 3D Global Climate Model (GCM). This GCM will be derived from the one that we have previously designed to simulate present day Mars. We will radically update it using new technologies to represent the details of the surface as well as all the processes that affected Mars when its environment evolved because of the oscillations of its orbit and obliquity, during changes in the atmospheric composition, or through events like meteoritic impacts or volcanic eruptions. Notably, we will highlight the last ten millions years that have been recorded in the polar layered deposits, whose formation will be simulated for the first time realistically.These new tools will address numerous enigmas found in Mars sciences. They will also offer a new platform to study specific processes such as the atmospheric escape through time or the chemical alteration of the soil. Furthermore,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Development of a Secure, Modular, Cash Checking Machine""' (EUROTHENTIC).

assistant: **Concept**

The euro represents the largest currency in circulation in the world and therefore an attractive target for counterfeiters with both the number and sophistication of counterfeits increasing since the euro’s introduction in 2002. To fight counterfeiting, the European Central Bank has implemented strict requirements under the Banknote Recycling Framework which require that no counterfeit notes are re-circulated by cash handling devices. In Northern Europe, today approx 15 000 point of sales systems are already equipped with both coin and note recycler systems and market in Europe is at a tipping point where self-service and self-checkout systems are gradually gaining in acceptance as a mainstream retail technology. These systems, integrated with the proposed EUROTHENTIC Cash Checking Machine system, will enable efficient and secure recycling of money. The advantages for the stores are secure and lower cost for cash handling due to amount of cash in store is reduced and also back-office work and CIT will be minimized. This will also enable cash back function - consumers to be able to withdraw cash directly at checkouts. While automated systems for validating bank notes are currently available, they have yet to find wide acceptance in the retail sector due to high capital costs and in particular performance considered slow by the sectors standards. The EUROTHENTIC project aims to overcome the current technical barriers to wide scale adoption of cash authentication technology by creating a low-cost, retrofitable cash validating module. The module will have the capability for high performance note processing and image recording, intelligent image analysis utilising a neural network approach and secure networking to provide remote system updates and a database facility for the