RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Efficacious vaccine formulation system for prophylactic control of influenza pandemics'.

assistant: **Objectives**

Influenza epidemics remain a burden to both human heath and national economies, as witnessed by the recent advance of pathogenic avian H5N1 influenza virus. While the numbers of human deaths in Europe have remained relatively low, the presence of such cases in Turkey demonstrates the danger posed by this virus. Now that the avian H5N1 has been detected in wild birds in numerous European countries, the PANFLUVAC consortium is committed to creating an efficacious vaccine against this virus, to provide strong protection in a pandemic situation.The overall aim of PANFLUVAC is to construct vaccine delivery systems for intranasal and parenteral vaccines. New H5N1 vaccines are to be based on well-established virosome technology - proven its worth for efficacious interpandemic vaccines - as well as whole virus vaccines. This will permit comparison of the intranasal virosomal vaccine with whole virus vaccine. The vaccine potency will be enhanced by novel adjuvants targeting dendritic cells, offering both antigen spa ring potential and immunopotentiation characteristics. Both ISCOMs and lipopeptide adjuvants are already proven immunopotentiators, biosafe for humans. Certain of these have been employed with experimental influenza vaccines, which allows the new H5N1 vaccines to be fast-tracked in their development. Accordingly, PANFLUVAC will generate the first H5N1 vaccine within the first 18 months of the project.The PANFLUVAC project is also designed to facilitate rapid modification of the vaccine in the face of virus drift. Within the pre-clinical evaluation, the new vaccines will be tested for the degree of heterotypic cross protection they offer. PANFLUVAC offers a generic vaccine development system to provide safe and efficacious vaccines against influenza, fitting with the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Health Care Advanced Networked System Architectures : Three Demonstrators for Eastern Europe' (HANSA-3DEMO), addressing dissemination and exploitation.

assistant: **Impact**

The aim of this project is the transfer of three demonstrators of distributed software technologies for open health care and hospital information systems in three pioneering hospitals.The overall objective is to transfer these technologies to the CEE countries. Five specific objectives will be pursued:  - to identify a strategy for the improvement of health care by the application of open system technologies, - to identify a methodology to migrate legacy systems to an open, modular architecture based on the DHE middleware, - to install DHE middleware in 3 hospitals, - to promote open systems technology, education and training,  - to create a market for HIS (health information systems) vendors, SMEs in general, both in EU and the CEE countries.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Protection of European seas and borders through the intelligent use of surveillance' (PERSEUS) targeting Seventh Framework.

assistant: **Abstract**

PERSEUS contributes to Europe’s efforts to monitor illegal migration and combat related crime and goods smuggling by proposing a large scale demonstration of a EU Maritime surveillance System of Systems, on the basis of existing national systems and platforms, enhancing them with innovative capabilities and moving beyond EUROSUR’s 2013 expectations, addressing key challenges: supporting the network created by National Contact Centres, Frontex and EMSA through increased capabilities, including transnational exchange of useful and available information, and associated procedures and mechanisms, thereby supporting the creation of a common information sharing environment generation of a common situational picture improved detection and identification of non collaborative/suspicious small boats and low flying aircraft enhanced and increasingly automated detection of abnormal vessel behaviours, identification of threats and tracking of reporting and non-reporting vesselsPERSEUS articulates this demonstration through 5 exercises grouped in 2 campaigns, implementing missions of drug trafficking and illegal migration control and delivering surveillance continuity from coastal areas to high seas.PERSEUS delivers a comprehensive set of validated and demonstrated recommendations and proposes standards.PERSEUS has assembled major users and providers, ensuring privileged access to existing surveillance systems and assets for an optimised coverage of the area of interest.  These users will define, assess and validate the alignment of PERSEUS’s recommendations to their needs. PERSEUS also includes an evolution mechanism to enlarge the user base and integrate emerging technologies during its lifetime.PERSEUS will augment the effectiveness of operational capabilities of the existing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Spatiotemporal multimode complex optical systems' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The STEMS project is about exploiting the new concept that has been recently introduced by the PI and his co-workers, namely the self-control of the spatial coherence of optical beams in multimode nonlinear optical fibers. This concept will enable a breakthrough technology, capable of delivering high-energy optical pulses with high-average powers and much higher beam quality from fiber lasers than what is possible today. High-power fiber lasers are largely limited by transverse mode instabilities, and the loss of spatial coherence in delivery fibers. Optical fibers provide the backbone of today’s internet communication networks, and enable compact, low cost light sources for a variety of industrial and biomedical applications. In most of these applications, single-mode fibers are used. Replacing single-mode fibers with multimode fibers leads to a dramatic growth of transmission capacity, and a substantial increase of average power and pulse energy from fiber lasers. However, because of spatial dispersion and resulting mode interference, multimode fibers suffer from an inherent randomization of the spatial transverse beam profile, leading to a loss of spatial coherence. My approach is to exploit the intensity dependent refractive index, or Kerr nonlinearity, of glass fibers to recover the spatial coherence of a multimode wave, and compensate for temporal modal dispersion.First, I propose to develop methods to control fiber nonlinearity, to compensate for temporal and spatial dispersion, thus preventing information spreading in the temporal domain, and coherence loss in the spatial domain. Second, by adding rare-earth dopants to multimode fibers, I will demonstrate self-control of modal dispersion and beam quality in active multimode fibers. Third, via the spatio-temporal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'High voltage network information exchange for planning and analysis' (ELECTRONET).

assistant: **Concept**

The key objectives for the ELECTRO-NET project are:- To establish a neutral data representation for generation and transmission in electric power systems, to be used for planning and operations analysis, to facilitate data exchange between and within organisations in the electricity supply industry.- To create an open system market for power systems software to ease the implementation of specialised applications into existing information systems.There will be four principal, consecutive, phases in the project:- Establishing a detailed user requirements specification for HV network data and information exchange.- Producing an integrated data model based on the requirements for equipment classification and network modelling.- A software development phase, implementing the new data model; this includes supervisory software, software tools and data translators to the neutral form.- The demonstration phase showing the project results in realistic applications.The impact and benefits of the results differ for utilities and software suppliers. Their way of exploitation of the results differs therefore as well. The utilities will incorporate the new standard in their applications. The greater ease of network data exchange between systems and between associated organisations will:- lead to improved efficiency with substantial savings in time and costs (e.g. for inter-connected studies);- improve collaboration between the European utilities and encourage joint ventures:- facilitate benchmark comparisons between different systems.The adoption of the agreed ELECTRO-NET standard will create an open market in electrical network analysis software which will facilitate the integration of specialised planning and analysis software with their own information systems. These advantages wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Deciphering the Recognition, Recruitment and Modification of structured lncRNAs by the methyl-transferase complex METTL3/METTL14 and its cofactors' (RRMs-lncRNA).

assistant: **Innovation**

The human METTL3/METTL14 methyltransferase complex (MTC) is responsible for the m6A methylation of a large set of RNAs, and plays a crucial role in tumorigenesis. It targets numerous long non-coding RNAs (lncRNAs), including Xist and MALAT1. To date, studies have only considered single-stranded RNA motifs, and a critical need for structural information on the complex in interaction with lncRNA has grown over the years. METTL3 and METTL14 form a heterodimer through their catalytic domains (MTDs). Additionally, each monomer comprises flexible regions that are essential to the complex activity but have been truncated because of their dynamics: the METTL3 tandem zinc-finger domains (ZFDs) and the RGG region of METTL14. Moreover, two cofactors of the MTC display a significant importance for its activity in vivo but have never been studied in interaction with lncRNA: the RNA Binding Motif protein 15 (RBM15) and the Zinc Finger CCCH-Type Containing 13 protein (ZC3H13). This project aims at understand how structured regions of lncRNAs are recognized by the functionally active MTC and its cofactors at an atomic level. For that purpose, we will measure the binding and methylation activity of both the ZFDs and RGG region to a set of RNA targets – corresponding to modified region of Xist and MALAT1 – in the context of the whole MTC with or without the cofactors. By using mutated and post-translationally modified protein, we will assess (i) the lncRNA binding cooperativity between ZFD and the MTD, (ii) the role of the RGG region methylation in lncRNA binding structure specificity, (iii) the role of the cofactors in lncRNA recognition. Finally, combining 13C methyl-TROSY experiments, segmental labeling, and paramagnetic relaxation enhancement, we will access the dynamics of the compl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'More electric, advanced hydromechanics propeller control components.', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The project proposal is aimed in category of Business Aviation/Short Range turboprop engines. The baseline core of ARDIDEN3 will be improved with focus, first of all upon combustion chamber for higher altitude operation, specific turbine and propulsive exhaust and specific control system. This way it will better fit with turboprop application. For this purpose the ARDIDEN3 core will be integrated with an innovative gear box, air inlet and advanced more electric propeller control system.Objective of the project proposal is to research, design, manufacture test and verify a new advanced, more electric propeller control system consisting of Propeller Control Unit, Overspeed Governor and Auxiliary Oil Pump, useful for operational conditions of the improved Turboprop engine developed by Turbomeca. The objective will be achieved by the following steps:1. Definition of propeller control system design specifications with respect to the increased level of power influences due to the specific characteristic of the improved Turboprop engine.2. Design of the Propeller Control Unit, Overspeed Governor and Auxiliary Oil Pump.3. Production of the Propeller Control System equipment.4. Testing of the Propeller Control Unit, Overspeed Governor and Auxiliary Oil Pump within internal testing procedures, and validation within environmental external testing and verification directly on the Turboprop engine demonstrator, in order to demonstrate the achievements.Based on the dynamic modeling, research and verification the new technical specifications will be established. Based on them a suitable, advanced more electric propeller control system will be designed, produced and tested.JIHOSTROJ is a company experienced and approved for design and production of propeller governors. VZLU is a resear
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Bacterial Adhesion Control through Surface TArgeted Regulation' (BAC-STAR) targeting Horizon 2020.

assistant: **Abstract**

Fundamental investigations of bacterial adhesion will create the knowledge base to advance surface engineering approaches.Directed mutagenesis of adhesin genes in several oral pathogens will be used to create a library of knockout strains. Recombinant adhesins will also be over-expressed in E.coli. Assays will be developed to test the interaction of the resulting strains (wild-type, knockouts, over-expressing E.coli clones) with a range of materials, covering the entire spectrum of surface properties with defined roughness, hydrophobicity, porosity, charge and composition. Adhesion kinetics will be monitored in real time, using flow cells to mimic the shear stress and nutrient exchange on implants in vivo. This will complement plate-based fluorescence adhesion assays, western blotting, immunofluorescence microscopy, and ELISAs. Adhesion trends will be tested with targeted surface modifications in pure and mixed culture, creating a feedback-loop for assay improvement with gradually specialised surface functionalization. The ultimate goal is to develop surfaces that promote the adhesion of host tissue, such as human osteoblast cells or gingival cells, whilst still preventing pathogen adhesion. Understanding the fundamental interactions of bacteria with surfaces facilitates the transferability of the results from this project to a variety of further applications (e.g. adhesion of electrogens to microbial fuel cell electrodes; antifouling surfaces etc.). My proposal therefore has the potential to be high impact research, and generates the framework for future interdisciplinary projects.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Mild Hybrid cOst effective solutions for a fast Market penetratiON'.

assistant: **Concept**

Mild Hybrid cOst effective solution for a fast Market penetratiON. THOMSON (Mild Hybrid cOst effective solutions for a fast Market penetration) project aims to the development of cost effective solutions, based on 48V architectures, answering the need in reducing the environmental impact of the transportation sector through a clever combination of advanced engines technologies, electrification and wider use of alternative/renewable fuels. The project addresses very precise and consistent objectives to support a quick transition towards high efficient, cleaner and affordable electrified powertrains focusing on the 48V architectures, intended as key element to increase fuel economy and reduce environmental impact and to support a quick penetration on the market of the hybrid powertrains.Approaches developed in the THOMSON project will demonstrate how the right combination of advanced engine downsizing/turbocharging technologies, coupled with a 48V motor-generator system, can provide the most cost effective solution for a rapid electrification through conventional vehicles. The project will provide an exhaustive evaluation of this concept through the development of two different 48V architectures (one integrating the e-machine on the front engine belt drive, the other between the engine and the transmission) on two different engine families: on one side a mid-size 1.6 litre Diesel engine and, on the other one, a small downsized Spark Ignited CNG engine equipped with a Direct Injection system. This twin approach will allow to demonstrate how 48V architecture interacts with Diesel technologies (especially with regard to noxious pollutant reduction) and, on the other side, with Spark Ignited CNG ones, emphasizing the CO2 reduction already achieved through the use of a low car
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Information Sampling in Multiattribute Choice'.

assistant: **Innovation**

Do we prefer a small flat with a short commute or a large house with a long commute? Many real-life decisions require combining information across different attributes. It has been shown that during such multiattribute decisions people serially attend to (or sample) a subset of the available information. The way this process takes place largely influences the final choice: for example, if the “commute” attribute is considered for longer, then the small flat will tend to appear better.Up to date, information sampling has been studied within the social sciences using eye-tracking techniques. However, in the context of choice tasks, the way eye fixations influence the upcoming choice is not precisely known and, thus, this line of research has not yielded any definitive mechanistic conclusions. Recently, theorists have proposed different mechanisms of information sampling but these proposals were not constrained by relevant data.I propose to fill this gap in a data-driven fashion by harnessing tools from sensory neuroscience. Using magnetoencephalography (MEG) we will simultaneously track the locus of attention and the tendency to choose one alternative over the other, during the entire time-course of a single multiattribute decision. This approach will enable us to unravel the computational and neural mechanisms that guide attention towards different aspects of a multiattribute choice problem. This project will yield a neurophysiologically detailed theory of multiattribute choice–from the level of neurotransmitters, to large-scale brain networks, to behaviour– that will ultimately shed light on century-long questions, such as why humans reverse their preferences irrationally, when irrelevant alternatives are added to the choice-set. The emerging framework will be useful to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Stochastic PDEs and Renormalisation' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

The field of stochastic partial differential equations (SPDEs) has been revolutionised in the last decade by breakthrough works of Hairer, Gubinelli-Imkeller-Perkowski, and many others. A new understanding of renormalised solution theories emerged, solving long-standing singular equations arising in various areas of probability and mathematical physics. The purpose of this project is to study a number of important questions in the field, open new directions, and challenge central open problems:(i) Launch the investigation of singular SPDEs that preserve Gibbs measures of distributional Hamiltonians such as the density of self-repellent polymers;(ii) Tackle the question of a quasilinear renormalisation formula, the last remaining component of the quasilinear solution theory;(iii) Develop an efficient quantitative approximation theory of singular SPDEs, removing the criticality barrier from the rate of convergence.