RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'High-throughput synthesis and characterisation of metal-organic framework thin films for volatile compound sensing' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Metal-Organic Frameworks (MOFs) offer the possibility to tailor their nano-pore environment and capture only specific molecules, making them an ideal candidate as a receptor in gas sensors. In order to mimic human olfaction, several receptors with different selectivity toward volatile organic compounds (VOCs) are combined in an array of sensors to form a so-called electronic nose (e-nose). High-quality thin films of MOFs are required for their integration in these sensor arrays; however, their synthesis has proven challenging due to a large number of parameters that influence the film quality.In the LibMOF project, a high-throughput (HT) synthesis method will be developed to screen the synthesis conditions for MOF thin films. The HT approach will be about 25-times faster than conventional synthesis and produce about 100-times less chemical waste. In addition, with the developed method, it is possible to deposit multiple different MOF films on a single substrate, which enables the use of HT characterisation of the functional performance (dielectric properties, adsorption isotherm and diffusion measurements of volatile organic compounds, VOCs). The synthesis conditions of the selected MOFs and their functional properties will be gathered in so-called libraries. These libraries will also contain negative results and will be shared publicly to facilitate faster development of MOF-based electronics. Finally, an electronic nose composed of an array of chemically-diverse MOF sensor elements will be fabricated and evaluated for sensing of complex VOC mixtures in real-world applications (targeting indoor air quality monitoring and human breath analysis for disease diagnostics).


**Keywords:** Metal organic frameworks
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Advancing Tools for Human Early Lifecourse Exposome Research and Translation'.

assistant: **Objectives**

ATHLETE aims to develop a toolbox of advanced, next-generation, exposome tools and a prospective exposome cohort, which will be used to systematically quantify the effects of a wide range of community-level and individual-level environmental risk factors on mental, cardiometabolic, and respiratory health outcomes and associated biological pathways during the first 2 decades of life, to implement acceptable and feasible exposome interventions, and to translate the resulting evidence to policy recommendations and prevention strategies.ATHLETE will establish a prospective exposome cohort, including FAIR data infrastructure, building on Europe’s most comprehensive already existing exposome data (18 cohorts in 12 European countries). ATHLETE will systematically characterise the effects of the exposome on early organ development, health trajectories, and biological pathways (metagenomic, metabolomic, epigenetic, ageing, and stress pathways), longitudinally from early pregnancy through adolescence. Innovative tool development will focus on: 1) complete and accurate measurement of multiple environmental risk factors (external/urban, chemical, physical, behavioural, social) through new targeted and untargeted exposure science approaches, 2) development of advanced statistical and toxicological strategies to analyse complex multi-dimensional exposome data, 3) development of interventions to reduce personal exposures, co-produced with the community, and 4) estimation of the societal impact of the exposome by calculating costs and child health impacts.ATHLETE’s strong focus on the vulnerable early stages of the life course, widespread general population exposures and common non-communicable diseases, its use of a large body of existing exposome data and expertise, its strong emphas
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Unsymmetric diborane(4) compounds for small molecule activation and B-B coupling'.

assistant: **Objectives**

Organoboron complexes are ubiquitous in synthesis due to their utility in functional group transformations and the Nobel Prize winning Suzuki-Miyaura reaction. Furthermore, the advent of frustrated Lewis pair chemistry and BB multiple bonds has demonstrated that organoboron compounds can activate small molecules (e.g., CO) and sigma bonds (including H2), reactivity previously thought to be the domain of transition metal catalysts. As part of the renaissance in organoboron chemistry diborane(4) compounds (R2B-BR2) have received considerable interest, particularly that react as boryl anion equivalents.  Recent unpublished work at UNIMAN has developed an efficient, scalable route to a synthetically useful unsymmetric diborane(4) compound, specifically (RO)2B-BCl2(NHC), (1, NHC = N-heterocyclic Carbene). The DIBOR project will exploit this breakthrough using 1 (and new congeners synthesised in this fellowship) as key precursors to;(i) readily synthesised cationic diboranes that are strong electrophiles able to activate small molecules and sigma bonds (C-H) and to diborylate pi nucleophiles; (ii) extended homocatenated boron compounds containing both electron precise B-B and B=B bonds. Advances in (i) will generate new transition metal free routes to diborylated hydrocarbons for use as synthetic intermediates. Whilst the demonstration of H-H and C-H activation will demonstrate that individual steps are viable for future application using diboranes in catalytic sigma bond transformations. Advances in (ii) will generate fundamentally new boron entities, e.g., electron precise B4 chains containing B-B and B=B bonds. The chemistry of electron precise boranes is in its infancy but dramatic differences in reactivity to the isoelectronic hydrocarbons have already been reported. Pre
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Role of NMDA receptor endocytic trafficking in the development of neural circuitry' under Sixth Framework.

assistant: **Concept**

NMDARs play essential roles in the development and refinement of neuronal connections by contributing to the maturation and stabilization of synapses and dendritic spines. A key step regulating synaptic stabilization is the transition from developmental to mature NMDAR subtypes during a critical postnatal period of brain development. However, little is known about the molecular mechanisms for removing or replacing NMDARs at the synapse.This proposal will investigate molecular/cell biological mechanisms that mediate the synaptic exchange of NMDARs, and the role they play in establishing appropriate synaptic connectivity. Our previous studies indicate that a principal regulator of NMDARs at immature synapses is the inhibitory NR3A subunit. Specifically, NR3A d irects for synaptic removal of NMDARs via rapid internalization. NR3A-mediated internalization is tightly regulated as it requires both activity and the recruitment of a neuronal-specific adaptor, PACSIN1/syndapin1. Our working hypothesis is that rapid dow nregulation of NMDARs-containing NR3A from synapses provide a critical signal that allows enhanced localization of mature NMDARs at synapses and thus stabilizes neuronal circuits during development. The experiments in this proposal are designed to test thi s model directly by analyzing how changes in NR3A expression affect the development of correct numbers of synapses and dendritic spines. The proposal represents a three-tiered approach to understand the role of specific pathways of NMDAR endocytic traffic king, starting with the basic characterization of a novel cell biological mechanism in vitro, the manipulation of molecular elements of this pathway to study its importance for the proper development of synaptic connections, and using a complementary genet ic a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Applying silicon solar cell technology to revolutionize the design of thin-film solar cells and enhance their efficiency, cost and stability' (2014-2020).

assistant: **Innovation**

Thin film (TF) photovoltaics (PV) hold high potential for Building Integrated PV, an important market as European buildings require to be nearly zero-energy by 2020. Currently, Cu(In,Ga)(S,Se)2 (= CIGS(e)) TF solar cells have high efficiency, but also a simple one-dimensional cell design with stability and reliability concerns. Furthermore, its present research has been mainly focused on improving the absorber and buffer layers. Scientifically, Uniting PV aims to study the practical boundaries of CIGS(e) TF solar cell efficiency. For that reason, its goal is to revolutionize the design of CIGS(e) solar cells through implementation of advanced three-dimensional silicon (Si) solar cell concepts. This novel design consists of (i) surface passivation layers and (ii) light management methods integrated into ultra-thin (UT) CIGS(e) solar cells: (i) Passivation layers will be studied to reduce charge carrier recombination at CIGS(e) surfaces. The aim is to create new understanding and thus scientific models. (ii) Light management methods will be studied to optimize optical confinement in UT CIGS(e) layers. The aim is to examine the interaction between light management and charge carrier recombination in UT CIGS(e), and to create scientific models. The main reasons to introduce these developments is to reduce charge carrier recombination at the CIGS(e) surfaces and in the CIGS(e) bulk, while maintaining optical confinement. Technologically, the project targets to establish a solar cell with: (1) Increased cell efficiency, at least 23.0 % and up to 26.0 %; (2) improved stability and reliability, due to reduced CIGS(e) thickness and passivation layers hindering alkali metal movement; and (3) reduced cost, due to the use of less Ga and In, and industrially viable materials, method
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Characterisations of wear mechanisms and surface functionalities with regard to lifetime prediction and quality criteria - from micro to the nano range' (WEMESURF), addressing dissemination and exploitation.

assistant: **Impact**

Almost all manufacturing techniques of surface preparing (polishing, lapping, deposition, etc.) have reached precision in nanometre scale. Although it is possible to measure sub micrometer structures of these surfaces (topography, thickness of coatings) there are hardly any information available for their functionality in tribological systems or wear characteristics due to nanometre or even micrometer surface effects.So there is a strong need for capable measuring devices and also for a higher level theoretical parameter model to predict behaviours of tribosystem and quality criteria of work pieces. Many nanometre scale measuring systems used for model tribometre and engine tests will provide the necessary data for the theoretical model. With this combination of different results in the theoretical model the real behaviour of tribosystems should be more predictable.So the objectives of this proposal are:- improved 3D-analysis-methods for determination of wear and chemical changes on advanced function al surfaces and coatings- improved analysis methods to describe chemical and metallurgical interactions between advanced lubricants and functional surfaces- set up a theoretical parameter and criteria model for wear characterisation in sub mi cro-metre and nano-metre scale- development of an improved micro-nano-simulation-model to describe the surface and advanced lubricant relevant interactions and wear mechanisms- economical impact of improved wear mechanisms understanding and ecological impact of wear reduction/preventionWithin this network the researchers will have the chance for linking their experience of one special topic to other institutes in respect to the superior parameter mode.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Advanced Materials and Electric Swing Adsorption Process for CO2 Capture' in the context of a Seventh Framework call.

assistant: **Objectives**

Carbon capture and storage (CCS) is one of the technological solutions to decarbonize the energy market while providing secure energy supply. So far, the cost of CCS is dominated by the CO2 capture, reason why new capture techniques should be developed.Adsorption techniques have already been evaluated for CO2 capture. So far, the main drawbacks of this technique are the energetic demand to regenerate the adsorbent and obtain high purity CO2. However, the utilization of commercially available materials was employed in the former evaluations. New materials with targeted properties to capture CO2 from flue gases can improve the performance of adsorption processes significantly.The vision of MATESA is to develop an innovative post-combustion capture termed as Electric Swing Adsorption (ESA). The utilization of hybrid CO2 honeycomb monoliths with high-loading CO2 materials (zeolites and MOFs) will be targeted. Classical ESA regeneration is done by passing electricity through the adsorbent, releasing adsorbed CO2 that can be recovered at high purity.A game-changing innovation in MATESA is the development of a regeneration protocol where electricity is only used to increase the purity of CO2 in the column and further regeneration is done using available low-grade heat. The predicted energy savings of the developed process may transform this CO2 capture process in a key component to make CCS commercially feasible in fossil fuel power plants going into operation after 2020.In order to realize a proof of concept of the proposed process, a strong component of the project will deal with the development of a hybrid material that is able to selectively adsorb CO2, conduct electricity, result in a low pressure drop and have reduced environmental impact. The development of such a mater
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Predicting the Regeneration of an Infarct by leveraging the Mechanobiology of Angiogenesis'.

assistant: **Objectives**

Acute myocardial infarction (AMI) is a significant global health issue. Current therapies cannot regenerate the hearts of survivors, leading to frequent AMI recurrence and premature death. Crucially, these therapies fail to induce sufficient blood vessel formation, i.e. angiogenesis, which is essential to regenerate the cardiac microvasculature. Without this vasculature, cells repopulating the infarcted tissue cannot survive. A deeper understanding and better control of post-AMI angiogenesis would thus transform patient outcomes. Cells in the infarcted heart experience complex, time-evolving mechanical environments. Despite the proven role of mechanical stimuli in regulating angiogenesis in other tissues, the impact of evolving cardiac mechanical cues on post-AMI angiogenesis is unclear. With PRIMA, I aim to mechanistically understand how these evolving cues affect post-AMI angiogenesis and how to leverage this new understanding to regenerate the microvasculature. I will achieve this aim by developing a revolutionary framework featuring in vitro and in silico models of cardiac angiogenesis. These models will address the evolving mechanical cues of the infarcted heart and the cell memory of past mechanical cues (mechanical memory). The new in vitro models will expose cells to mechanical cues mimicking the cardiac tissue. The resulting insights will inform multiscale computational models to predict angiogenesis and its subcellular mechanisms in response to macroscale changes in cardiac mechanical cues. The multiscale simulations, validated by in vitro models, will finally translate the in vitro findings to the complex in vivo setting and will identify new strategies to restore the microvasculature post-AMI.Building on this unique idea and multidisciplinary approach, PRIMA
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Adstreff expansion'.

assistant: **Concept**

The ADSTREFF network is scheduled to commence in January 1998. ADSTREFF is currently a network of 16 CEU-funded projects all of whom will participate in, and contribute to, the work packages detailed in the technical annex to the contract, which also contains the rationale and reasoning behind the ADSTREFF concept. This proposal is submitted to expand the ADSTREFF network to include a further 8 CEUfunded projects. These projects are currently undergoing contract negotiation and will themselves be commencing in early to mid 1998. The ADSTREFF EXPANSION programme will run from June 1998, for a period of 30 months, to finish at the same time as the ADSTREFF programme in December 2000. The new projects, once incorporated in the ADSTREFF network, will perform the same function and role as the project members. The ADSTREFF Network will provide a forum under which the needs of industry and the opportunities of the market may be analysed and a clear vision of the future defined. It will enable industry and the Commission to generate a clear plan for future research to benefit most from being carried out as a series of collaborative projects with a European dimension. The research will be of non-competitive nature and generally at a scale beyond the resource of individual companies or even member nations working on their own. By clustering current research projects ADSTREFF will be used to provide a tactical review of the present state of the art and develop a strategic way forward. The breadth of the subject implies a high degree of complexity and so a framework in which developments can be collected, reviewed and guided toward an integrated research programme is vital to achieve maximum benefit from current and future research activities.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Drying of complex fluids on soft substrates'.

assistant: **Objectives**

The study of soft materials has received a growing attention in last decades.Broadly speaking, these materials present viscoelastic properties giving them the ability to be highly deformable.Recently, new interests have been found in the wetting of soft deformable surfaces because of the many applications in material science, chemistry and biology for cosmetics, medicine, new printing technologies...On the other side, significant results has been obtained on the drying of complex fluids composed of a volatile solvent and solid particles, like the drying of a coffee drop resulting in a remarkable coffee stain effect.These studies generally involve non-deformable surfaces.Our project aims to bring together, for the first time, these two topics independently studied in the litterature.The proposal consists in an experimental study of the drying of a colloidal drop on deformable gels of different properties: elasticity, viscoelasticity and swelling.The objective is to describe the impact of gel mechanical properties on the drying process, contact line dynamics, resulting deposit shape and crack patterns.The proposed research will provide an overview of expected drying regimes as a function of substrate properties.This study will be completed with a theoretical analysis of the experimental results to provide complementary insights on observed phenomena.Moreover, applications, toward biology in particular, will retain our attention throughout the whole project since the returning host institution is active on this subject.The fellow will benefit from hosts expertise on gel chemistry and theoretical modeling to attain a leading independant position.The outgoing host is an expert in elastocapillarity and the return host in contact line dynamics and coating.""