RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Complex Fluids in Fractured Geological Media for Enhanced Heat Transfer' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

GEONEAT aims at unraveling the potential of engineered shear-thinning (ST) fluids in enhanced geothermal systems to improve heat recovery efficiency and in heat tracer tests to infer structural parameters of deep hot reservoirs. Cutting-edge interdisciplinary methodologies from applied mathematics and hydrology are merged in a novel framework to achieve two scientific objectives: (1) characterizing quantitatively how using engineered fluids impacts coupled flow and heat transfers in fractured media at all scales; (2) inferring structural information on fractured media from coupling inverse modeling to field measurements of the heat exchange using complex fluids of different rheologies. To this aim, two technical challenges will be tackled: (1) the development of a multiscale model of coupled flow and heat transport in fractured geological formations; (2) the obtention of experimental data in a synthetic analog medium, to validate the model and constrain an inverse model for characterizing the medium’s geometry. GEONEAT relies on the expertise of a top-notch consortium consisting of the University of Bologna (beneficiary, supervisor Prof. Vittorio Di Federico and co-supervisor Prof. Valentina Ciriello, experts in subsurface stochastic modeling), Stanford University (outgoing phase, supervisor Prof. Daniel M. Tartakovsky and co-supervisor Prof. Roland Horne, experts in uncertainty quantification, inverse modeling, and geothermal energy), and the University Rennes 1 (secondment, supervisor Prof. Yves Méheust and co-supervisor Dr. Maria Klepikova, experts in subsurface heat transfers and analog experiments of flow and transport). Dr. Lenci will receive excellent training in the three institutions to pursue outstanding research, propelling his career development towards beco
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Seismic Protection of Historical Buildings by Reversible Mixed Technologies' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

The research project PROHITECH is framed within the INCO thematic areas INCO-B.2, INCO-2002-B2.1 and INCO-2002-B2.2, devoted to Protection and conservation of cultural heritage" in the Mediterranean area. The project tackles the important subject of the seismic protection of historical and monumental buildings, namely of constructions dating back from the ancient age up to the mid of the 20th century. The objective is to develop sustainable methodologies for the use of reversible mixed technologies in the seismic protection of existing constructions, with particular emphasis to buildings of historical and artistic interest. Reversible mixed technologies exploit the peculiarities of innovative materials and special devices, allowing ease of removal if necessary. At the same time, the combined use of different materials and techniques yields an optimisation of the global behaviour under seismic actions. The endpoint of the research is a proposal of codification for the use of such technologies in the seismic protection of existing constructions, which will meet the most up-to-dated codification issues at European level and will comply with layout, language and philosophy of structural Eurocodes. The research program involves 15 academic institutions coming from 12 Countries mostly belonging to the South European and Mediterranean area. The work plan is based on 12 scientific work packages, plus 3 management work packages. A number of 12 scientific workpackage deliverables is foreseen. The scientific activity is broken down into 4 parts, aiming at producing 4 main deliverables in 3 years, which are intended to yield a significant advancement of the state of the art in the field of seismic protection. An intense activity of result dissemination at European level is also env
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Pilot plant for environmentally friendly animal by-products industries' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

A by-product is defined as a secondary product obtained during the manufacture of a principal commodity. Animal by-products (ABPs) are materials of animal origin that people do not consume. Animal by-products represent a significant part of the biowaste stream and disposal options are limited and highly regulated. Over 20 million tons emerge annually from EU from slaughterhouses, plants producing food for human consumption, dairies and as fallen stock from farms. In Europe, there is an increasing requirement for selecting solutions which demonstrate the best available technique for the treatment of animal by-product wastes.The PILOT-ABP project aims at developing new eco-innovative technologies associated to the animal by-products process, which allow on one hand an environmental improvement of the process, thanks to a more efficient consumption of the energy used in the process and a better recovery of raw materials, with a related decreasing in wastes production, and on the other hand an increasing of the added value of the obtained products which leads to a better financial profitability of SMEs.The specific objectives of the project are:Application of new extraction technologies in order to obtain animal oils with higher oleic acid content.Obtaining of biodiesel from animal oils for partial substitution of use crude fuels use and decreasing of pollutant emissions.Application of low temperature pyrolysis techniques to meat and fish protein flour for bio-oil obtaining, as a source of chemical products, and coal for reducing the consumption of natural energy sources.Obtaining of gelatin and collagen for manufacturing functional and biodegradable  biopolymers more ecological and sustainable.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Microbial ecology: the relationships between community diversity, structure and function' to be submitted under Sixth Framework.

assistant: **Abstract**

Microbial activity underpins the functioning of all global biogeochemical cycles. Microbial ecology, the interaction of microorganisms with their environment, is an essential component in understanding the functioning of the global ecosystem. Fundamental to microbial ecology are the principals that determine the structure and function of microbial communities. Only when these principals are understood will the full impact of microbial activity on the global ecosystem be apparent. Microbes play a major role in many scientifically, economically and socially important areas and represent a vital area of research within the EU. However, microbial ecology is a difficult science that at present lacks a strong theoretical basis.This proposal will address fundament al issues related to microbial biodiversity and place these within an ecological context. This will be achieved by two general approaches. The first will link microbial community structure and function by investigating two indigenous microbial genera as mo del generalist and specialist microbes using metagenomics, gene expression analysis, distribution ecology and traditional isolation and characterisation analysis. The second will investigate microbial phenotypic and genotypic stability. This approach will utilise model systems in chemostats and compare these with natural communities.This work will help define the true ecological context of microbial biodiversity and so redefine microbial ecology. The proposed research is novel and ambitious in its aims and will place Europe at the forefront of hypothesis-driven research in microbial ecology. It will produce four highly skilled, multi-disciplinary researchers with excellent international reputations and career prospects. Building a strong European research base in m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'COFUNDing of the CERN Fellowship Programme 2012' in the context of a Seventh Framework call.

assistant: **Objectives**

For many years, CERN has operated a trans-national Fellowship programme, offering scientists and engineers challenging opportunities in particle physics research, and in related fields of physics and technology. CERN secured COFUND grants in 2008, 2010 and 2011. They offer CERN a timely opportunity to enhance the mobility element of this programme without nationality limitations. The 2012 Call comes at a time when the start-up of the Large Hadron Collider has made CERN one of the most exciting places to work for the global physics and technology community.Applicants will propose their own research projects. Selection will be based on the scientific potential of the proposal, and on the demonstrated excellence of the candidate. Working on frontier research and technology projects and profiting from the unique facilities available at CERN, the co-funded Fellows will deepen their knowledge in their own field and acquire international visibility and reputation. They will broaden their skills using the numerous training opportunities and through their exposure to an interdisciplinary and multi-national environment. Inter-sectoral skills will be fostered through CERN’s industrial collaborations and technology transfer projects.Employment conditions will be improved by offering three-year appointments rather than the standard two-year terms of CERN Fellows. At least two of these three years will be spent at CERN. We consider this provision to be justified by the size of the Laboratory, the diversity of the research and training opportunities, and by the uniqueness of CERN’s facilities. However, mobility will be enhanced through the opportunity to spend up to one third of the Fellowship in external institutions, including industrial laboratories, on secondment from CERN under t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Targeting the mutated PI3Kα isoform for the development of novel anti-cancer agents' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

The application of rational drug design is proven to be more efficient than the traditional way of drug discovery since it aims to understand the molecular basis of a disease. The aim of this project is to deactivate the mutated cancerous PI3Kα protein with small molecule inhibitors. It was recently established that PIK3CA, the gene encoding the catalytic p110α subunit of PI3K, is frequently mutated in human malignancies. 80% of these mutations result in amino acid replacements located in either one of two hotspots: (a) in the helical domain the most common replacement is that of Glu by Lys in exon 9 (E545K), (b) in the kinase domain, a His is changed to Arg in exon 20 (H1047R). Both types of these mutations increase the kinase activity of the enzyme, upregulate the downstream AKT pathway and VEGF signaling, and thus stimulate tumorigensesis and angiogenesis. Several PI3Kα inhibitors have been reported in the literature; however, these non-selective antagonists target both the carcinogenic and wild-type PI3Kα proteins, causing undesirable side-effects. Selective inhibition of the mutated carcinogenic PI3Kα isoform is therefore a promising target in cancer research. In this joint computational and experimental study, we propose to selectively inhibit the mutated carcinogenic form of PI3Kα with small-molecule inhibitors through structure-based drug design, synthesis of potential leads, and in vitro/in vivo assaying. Following the assays, potent compounds will be iteratively optimized for both pharmacological and structural properties with computational methods and re-assayed for enhanced activity. Moreover, Molecular Dynamics simulations will be performed in order to gain insight into the dynamics of the mutated protein and the mechanism of oncogenesis. Overall, this stud
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Interacting Photon Bose-Einstein Condensates in Variable Potentials' in the context of a Seventh Framework call.

assistant: **Objectives**

Bose-Einstein condensation, the macroscopic ground state occupation of a system of bosonic particles below a critical temperature, has in the last two decades been observed in cold atomic gases and in solid-state physics quasiparticles. The perhaps most widely known example of a bosonic gas, photons in blackbody radiation, however exhibits no Bose-Einstein condensation, because the particle number is not conserved and at low temperatures the photons disappear in the system’s walls instead of massively occupying the cavity ground mode. This is not the case in a small optical cavity, with a low-frequency cutoff imprinting a spectrum of photon energies restricted to well above the thermal energy. Using a microscopic cavity filled with dye solution at room temperature, my group has recently observed the first Bose-Einstein condensate of photons.Building upon this work, the grant applicant here proposes to study the physics of interacting photon Bose-Einstein condensates in variable potentials. We will study the flow of the light condensate around external perturbations, and exploit signatures for superfluidity of the two-dimensional photon gas. Moreover, the condensate will be loaded into variable potentials induced by optical index changes, forming a periodic array of nanocavities. We plan to investigate the Mott insulating regime, and study thermal equilibrium population of more complex entangled manybody states for the photon gas. Other than in an ultracold atomic gas system, loading and cooling can proceed throughout the lattice manipulation time in our system. We expect to be able to directly condense into a macroscopic occupation of highly entangled quantum states. This is an issue not achievable in present atomic physics Bose-Einstein condensation experiments. In the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Theoretical description of the multifaceted aromaticity and resonance effects in the ground- and excited-state molecular systems' (MulArEffect).

assistant: **Concept**

Aromaticity and bond resonance are the key concepts in chemistry that rationalize the structure and reactivity of countless number of chemical species. Qualitative assessment of aromaticity and the resonance stabilization effects is crucial for understanding different phenomena in photochemistry, catalysis, organic electronics, supramolecular chemistry, molecular biology etc. However, the real predictive power of these concepts is still dramatically understated, since many of the currently used methods of aromaticity quantification suffer from serious methodological flaws, interpretative mistiness, and computational complexity, which cuts back their applicability to relatively simple molecules. Assessment of aromatic stabilization within the large-scale perspective regarding macrocycles, (bio)catalysts, functional materials, etc., is still a challenge for both experimental and computational chemists. The long-term goal of this project is to understand how aromaticity and different resonance effects determine the physicochemical properties in such systems. In the first goal of this proposal, we aim to develop a novel computational method called EDDB that provides both a detailed description of local aromaticity of selected molecular fragments as well as the bird's-eye view on the global aromaticity of nanoscopic-size molecules and assemblies at a reasonable computational cost. The second research goal of the proposal is to use the EDDB method to gain insights into the mechanisms of the resonance-driven phenomena in the multifaceted aromatics that are instrumental in the design of new catalysts, spin-bearing materials, organic field-effect transistors, etc. Applications in the field of enzyme design and drug discovery are also expected in the long-term. After the executio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Sensitive, spatially resolved U-Th dating approach using LA-ICPMS' in the context of a Horizon 2020 call.

assistant: **Objectives**

The U-Th dating system is broadly exploited to determine the timing and process of Earth’s geological, environmental, and biotic evolution for materials as young as few years to over the last 800 thousand years (kyrs). Contemporary solution phase U-Th dating protocol using thermal ionization mass spectrometry (TIMS) or multi collector-inductively coupled plasma mass spectrometric (MC-ICPMS) can provide high precision dates with errors of ±1-4‰ (2σ) on ages from 5 to 100s kyr; however, it still restricted by the discrete milli-domain (mm) sampling strategy and the time-consuming chemical preparation procedure.Laser ablation-inductively coupled plasma mass spectrometric (LA-ICPMS) could serve the strengths of rapid, in-situ, and high lateral scanning to U-Th dating. Until nowadays laser U-Th dating approach is sparsely reported due to its reduced sensitivity and precision. Here the experience researcher (ER) designs and employs methods by means of a solution-based correction strategy with a jet-interface setup. This new configuration could essentially reduce the uncertainties and enhance the sensitivity significantly. Based on the ER's previous training, he has firm knowledge and skills in conducting high precision carbonate U-Th dating protocol using MC-ICPMS (Shen, Wu et al., Geochim. Cosmochim. Acta, 2012), and the anlaysis of rare earth elements using LA-ICPMS (Wu et al., Anal. Chim. Acta, 2018). The expected outputs of this SPATULA project are: 1) improve the resolution of age assignments from the milli-domain (mm) to micro-domain (μm). 2) provide in situ analysis using LA-ICPMS to overcome time-consuming element separation processes requiring hazardous chemicals. 3) apply this μm-domain laser U-Th dating approach to tephra-containing stalagmite samples, to reconstru
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'EEN-Innovation PT' (2014-2020).

assistant: **Innovation**

The objective of this project is to contribute to smart growth in the European Union by increasing the efficiency and effectiveness of investments in RD&I and by contributing to a better and more efficient connection of actors along the innovation chain.  In order to achieve the above objective, 2 main target groups and 2 specific objectives are defined:a) beneficiaries of the SME Instrument  at this level, the specific objectives consist in identifying  bottlenecks to the creation of economic impact in companies benefitting from grants by Horizon 2020 SME Instrument and address these bottlenecks with the help of capable coaches. This service to beneficiaries of the SME Instrument is called 'Key account management'(KAM) and 22 of these services are foreseen.b) selected small and medium-sized enterprises with significant innovation activities and a high potential for internationalisation, which could potentially become beneficiaries of European support in terms of research and innovation but without effective access to consulting services for innovation management. At this level, the specific objective is: to increase the efficiency and effectiveness of innovation processes in those companies. This service, provided independently from a specific innovation project and focused on a company's innovation management system, is called 'Enhancing the innovation management capacity of SME” (EIMC) and 137 of these services are foreseen. In summary, the partners participating in this project (IAPMEI, ADI, CCIPD, CEC and INESC) expect to deliver a total of 159 services covering all the country. The project respects the excellence, 'no wrong door', proximity, subsidiarity and additionally principles as well as the mechanisms of signposting and follow-up of target audience inside th