RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Architecture of Peripheral Neuroimmune Circuits and Synapses'.

assistant: **Innovation**

Maintenance of health requires the coordination of multiple cellular networks. For example, the immune and nervous systems cooperate to regulate tissue homeostasis. In agreement, our recent work demonstrates that innate lymphoid cells (ILC) integrate neuronal signals to control tissue health and immunity. These findings are provoking a paradigm shift in our understanding of the immune response, neuroimmune crosstalk and its potential therapeutic value. Nevertheless, the dynamics of neuroimmune modalities remain elusive, and progress in the field has been hindered by the lack of approaches to explore the identity and plasticity of neuroimmune interactions in vivo.Here, we hypothesise that dynamic circuitry codes orchestrate neuro-ILC2 interactions and disease outcomes. To test this hypothesis, we have developed a set of disruptive intercellular labelling neuroimmune toolboxes that we termed KISS and LIPSTIC, and which can probe the dynamics of neuro-ILC2 axes in vivo, with cellular specificity and single-cell resolution. Using these innovative platforms, we plan to unravel the architecture of pulmonary neuro-ILC2 circuits and to define cellular identities, outcomes, and plasticity at the neuroimmune interface. Sequentially, we propose to unravel unappreciated neuro-ILC2 synaptic communication and to define the ultrastructure of theses intercellular entities using high-resolution imaging. Finally, by conditionally harnessing the activity of synaptic neuronal partners during airway inflammation and infection, we will investigate their impact on ILC2, their environment, and on disease progression.Together, these experiments will tackle multiple facets of pioneer, frontier questions, bringing to bear an array of cutting-edge technologies to address and advance, with unpreced
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Corals and global warming: The Mediterranean versus the Red Sea', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

CoralWarm will generate for the first time projections of temperate and subtropical coral survival by integrating sublethal temperature increase effects on metabolic and skeletal processes in Mediterranean and Red Sea key species. CoralWarm unique approach is from the nano- to the macro-scale, correlating molecular events to environmental processes. This will show new pathways to future investigations on cellular mechanisms linking environmental factors to final phenotype, potentially improving prediction powers and paleoclimatological interpretation. Biological and chemical expertise will merge, producing new interdisciplinary approaches for ecophysiology and biomineralization. Field transplantations will be combined with controlled experiments under IPCC scenarios. Corals will be grown in aquaria, exposing the Mediterranean species native to cooler waters to higher temperatures, and the Red Sea ones to gradually increasing above ambient warming seawater. Virtually all state-of-the-art methods will be used, by uniquely combining the investigators expertise. Expected results include responses of algal symbionts photosynthesis, host, symbiont and holobiont respiration, biomineralization rates and patterns, including colony architecture, and reproduction to temperature and pH gradients and combinations. Integration of molecular aspects of potential replacement of symbiont clades, changes in skeletal crystallography, with biochemical and physiological aspects of temperature response, will lead to a novel mechanistic model predicting changes in coral ecology and survival prospect. High-temperature tolerant clades and species will be revealed, allowing future bioremediation actions and establishment of coral refuges, saving corals and coral reefs for future generations.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'NEXT-GEN OF SUSTAINABLE BIOBASED CHEMICAL PLATFORMS AND POLYMERS: ENHANCING SUSTAINABILITY IN EUROPEAN INDUSTRY', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Successfully scaling up the sustainable and biodegradable materials is essential for the future growth of European industry. To compete with well-established fossil-based chemicals, biobased alternatives need to solve the triple equation of environmental, safe, economic and societal performance. At the same time it must be economically viable on an industrial scale and possess properties akin or superior to existing petroleum-derived analogues. Few biobased polymers have met this challenge. NEXT-STEP will build on the H2020 BioCatPolymers project to demonstrate a sustainable, safe and economically viable production process for a new chemical platform with large scale applications, notably in the bio-based polymer market. NEXT-STEP will use Harwdood sugars produced from sustainably managed forest at the flagship plant of the project partner Fibenol. NEXT-STEP has defined ambitious KPIs for its process regarding its economic performances as well as its Biomass and Energy efficiency. The new chemical platform, the 3-methyl-d-valerolactone (3MdVL) will improve the sustainability and recyclability of polyurethane (PU) products and unlock new engineering plastic applications for Polylactic acid (PLA) co-polymers. Together with its derivate 3-methyl 1,5-pentanediol (3MPD), the 3MdvL can also be used as a biobased polyol component in the traditional PU and other plastic production processes.NEXT-STEP will demonstrate the applicability of its chemical platform by demonstrating its use as a feedstock for the production of (i) Polylactic acid (PLA) co-polymers for shoe outsole, and of (ii) recyclable Non Isocyanate Polyurethane foams for shoe mid-sole and insulation materials applications. Five other applications will be selected for demonstration together with the polymer industr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Multimodal Immersive Motion Rehabilitation with Interactive Cognitive Systems' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The main hypothesis of this project is that movement training for neurorehabilitation can be substantially improved through immersive and multimodal sensory feedback. The approach is real-time acquisition of behavioural and physiological data from patients and the use of this to adaptively and dynamically change the displays of an immersive virtual reality system, with the goal of maximising patient motivation. This will result in complex systems that are natural, user-friendly and easy to use.<br/>In this project two exemplary systems will be developed for robot-assisted rehabilitation of upper and lower extremities. The systems will be able to record multi-sensory data (motion, forces, voice, muscle activity, heart rate, skin conductance etc.) and process this data in real-time to infer the intention of the patient and the overall psycho-physiological state. The computed information will be used to drive the therapy robots in combination with immersive virtual reality systems including 3D graphics and 3D sound. Several individually adjustable scenarios will be set up and the patient will be immersed into the corresponding virtual environments. Experimental tests on humans will evaluate to which such systems can increase the motivation of the patients and, thus, the therapeutic outcome of the training.  <br/>New basic insights will be obtained about presence and motivation in humans. Furthermore, MIMICS technology will enter clinical routine so that large patient populations (e.g. stroke, spinal cord injury) can benefit. Motor rehabilitation will become more efficient and may reduce costs of the European health care systems. A multi-national network is required to better compensate regional differences and increase international acceptance. The MIMICS consortium is cha
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'City-zen, a balanced approach to the city of the future""' in the context of a Seventh Framework call.

assistant: **Objectives**

City-zen deals with the development of the city of the future. The project has three major goals, 1- to realize more effective collaboration models and a methodology for development of smart cities, 2- to connect with industry, and have them develop technology to the benefit of smart cities and 3- to showcase to society ambitious pilot projects. Main idea for this project is that after successful implementations in topics such as district heating, energy grids, local energy generation, energy efficiency for housing, now it is time for the next big step:  integrated flexible open infrastructures.The approach  taken is the set-up of stakeholder teams in the demonstrator cities, to accelerate the realization of energy-efficient city development. This effort is supported by technology teams including industrial parties. Workshops aiming at decreasing the gap between innovation and implementation will be organized and knowledge-disclosing material will be developed by specialized working groups in retrofitting, smart grids, and heating and cooling. This approach holds for both technology and process improvement.The demonstrators in Amsterdam and Grenoble include retrofitting 105000 m2 of housing to levels down to 53 kWh/m2, showing average savings of the order of 80%. Furthermore they include fully-functional smart grid development, electricity storage demonstrators, free cooling schemes and district heating efficiency improvements.The City-zen project recognizes the key position of citizens, so ample attention is paid to dissemination and education of this group. Serious gaming is included as part of the work, as well as a roadshow bringing the results of the project right at the doorsteps of decision makers in other cities.Extensive monitoring of all buildings and installa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Distributed Ledger Technology: Innovation & Ecosystem Management' to be submitted under Horizon Europe.

assistant: **Abstract**

Early evidence suggests that participants in Blockchain ecosystems have to resolve technological, innovation, governance and stakeholder management tensions at different levels: organizational (internal innovation development and management), ecosystem (alliances, platform emergence) and individual level (consumer, user adoption). Industry, Government and research bodies must join forces and share expertise to properly investigate the phenomenon and maximize the societal and economic impact of Blockchain technology for EU and global entities. Given that Blockchain technology exists at the intersection of these three different levels of analysis (organizational, ecosystem, societal) it is impossible to study the phenomenon without taking into consideration the dynamics that are created at the intersection of these levels. DIEM consortium brings together academic, government and industry expertise to holistically investigate the managerial, economic and societal implications of Blockchain technology. DIEM is a Doctoral Network (Industrial Doctorates) that creates a platform for researchers to engage in the co-production of knowledge by investigating state-of-the-art challenges and societal implications of Blockchain technology across actors and industry boundaries. It has a significant potential for creating an impact on careers of PHDs, as transforming Europe into a society capable of building its competitiveness on digital technology requires developing a new generation of responsible researchers with the competency to understand how fundamental shifts in digital technology impact across businesses, industries and society.


**Keywords:** ecosystems, emerging technologies, strategy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'The first European daggers: Function, meaning, and social significance'.

assistant: **Innovation**

The researcher is moving from Italy to Newcastle University (United Kingdom) to carry out EuroDag, the first ever comparative study of the function of early European stone and copper/bronze daggers, c. 3800-1500 BC. The EuroDag project aims to understand how early daggers were used, for what purposes, and in which social contexts, while also exploring whether meaningful functional differences could be discerned amongst this broad class of objects based on manufacturing technology, chronology, typology, or regional distribution. The research problem will be addressed through an original combination of museum- and lab-based microwear analysis (to be conducted on 300 prehistoric flint and copper/bronze daggers from Italy, central Europe and Iberia) and wide-ranging functional experiments with purpose-built replica daggers. The importance of the project is threefold: (1) this is the first comprehensive functional analysis of a class of objects that, though widespread in Neolithic and Early Bronze Age Europe, is still poorly understood; (2) it is the first attempt ever made to examine both flint and metal daggers as a coherent set of artefacts; and (3) it is the first time that a researcher tries to develop a unified experimental and analytical methodology for the investigation of both stone and metal objects from world prehistory. The research will dramatically reshape the agenda of European prehistory by revealing the functional basis of the social significance and fortune of early daggers. Whilst working on the project, the researcher will acquire new skills in prehistoric metallurgy, experimental archaeology, and metalwork wear analysis; she will also develop valuable experience in teaching and lecturing, academic writing, and public outreach. In turn, she will transfer
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'AI on-demand platform for regional interoperable Digital Innovation Hubs Network', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

In 2019, SMEs accounted for 99.8% of all enterprises in the EU-28 non-financial business sector and accounted for the majority of the increase in value added (60%) – EU Annual Report on SMEs, (November 2019). In the last years, the EC acknowledged that a number of areas require immediate action at EU level to ensure that: (1) SMEs will increase Europe’s competitiveness in the AI landscape leaving no SME behind (2) New technologies and AI-based product, processes and services are based on European ethical values (3) SMEs get fast, trusted and secure links to data assets, AI methods and tools that can be used expediently and build on digital sovereignty. DIHs (Digital Innovation Hubs) are a fundamental European instrument that has emerged over the last decade to address these limitations and encourage the uptake of AI across the economy.We simply need to establish the most needed link between the DIH engine and the AI4EU service platform power to ignite a virtuous cross-sectorial European economy of intelligence for SMEs at scale; precisely the SME-friendly AI vision that DIH4AI aims at fulfilling.The DIH4AI project aims at building a network of AI-on-demand innovation and collaboration platforms, supporting joint development and provision of ecosystem-business-technology-transformation services through a sustainable network of regional DIHs specialized in AI and targeting local SMEs and local tech governmental agencies. The DIH4AI regional platforms are by design interoperable with the pan-EU AI4EU platform thanks to an interoperability framework operating at Portal, Data and Cloud levels, allowing SME-DIH-EU virtuous bi-directional collaborations at the level of shared AI resources, AI-oriented standard data models and ontologies, AI ready FAIR datasets, AI-driven user
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Extracytoplasmic Function (ECF) Sigma Factors: From Regulatory Specificity to Synthetic Switches' under Seventh Framework.

assistant: **Concept**

Bacillus subtilis is a model organism for basic and applied research that has been intensively studied for more than two decades in the course of EU-funded research consortia and – with the FP7-project BaSynthec – has recently entered the age of Synthetic Biology (SynBio). This emerging interdisciplinary research area has a huge potential for biotechnological applications and is a major focus of upcoming EU-funded research initiatives, as reflected by the first transnational ERASynBio call this year and the focus of the EU-program Horizon 2020 on innovation and biotechnology. Based on the comprehensive knowledge of B. subtilis biology, its potential as an important chassis for future SynBio applications is unquestioned. But the lack of standardized tools for designing and implementing in vivo expression programs for metabolic engineering currently limits its use. It is the aim of this project to contribute to such a genetic toolbox by exploiting the enormous potential of Extracytoplasmic Function σ factors (ECFs). These transcriptional regulators provide a huge reservoir for developing SynBio switches. But since their diversity, specificity and ubiquitous distribution has only recently been discovered by the host group, ECFs have so far not been used for SynBio purposes. Using the comprehensive knowledge of the host group on B. subtilis genetics, ECF biology, and SynBio rationales, this project aims at developing innovative orthogonal ECF-based switches and devices for controlling complex expression programs in B. subtilis, based on novel actinobacterial ECF groups. The success of this project, set at the interface between basic molecular research and SynBio application, furthermore builds on the applicant’s strong expertise in bacterial genetics, the superb infrastruct
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Inclusive and Interconnected Ecosystem to Boost Paediatric Innovation in Europe-i4KIDS-EUROPE' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Innovation in paediatric health is critical to ensure that children, regardless of their age, health condition, socio-economic situation or place of birth, have access to the life-changing healthcare solutions they need to grow-up stronger and contribute to a better society. Children are not just small adults and they need targeted innovative solutions. However, paediatric innovation is still elusive. There are two main causes for this:i) Stakeholders perceive paediatric innovation as risky and they just try to adapt adult solutions to children.ii)  Paediatric experts, innovators and other relevant stakeholders are scattered in a fragmented ecosystem across Europe failing to identify opportunities or deliver effective and harmonized action.Thus, the unexploited innovation potential is large, particularly in emerging and moderate innovator countries. To reduce barriers and exploit these opportunities, while ensuring equality across different countries, the establishment of a European Paediatric Innovation Ecosystem is of paramount importance.The i4KIDS-EUROPE project builds on an existing successful initiative (i4KIDS), and it will expand its activities towards Europe in order to enlarge the participation of diverse European paediatric stakeholders and territories.  The project will allow synergies, avoid duplications, reduce differences between strong and emerging/moderate innovator territories and strengthen competitiveness to optimise the innovation potential of the European paediatric sector. To achieve this, we will analyse the landscape of paediatric innovation in Europe as well as the barriers that emerging/moderate innovator countries face. i4KIDS-EUROPE will offer an interconnected paediatric innovation ecosystem that will capacitate its underrepresented actors