RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Characterization and Recovery of Bionanoparticles for Vaccine Delivery and Gene Therapy'.

assistant: **Innovation**

The Doctoral Network CAARE - “Characterization and Recovery of Bionanoparticles for Vaccine Delivery and Gene Therapy” focuses on a rapidly emerging field in biopharmaceutical industry and a new class of molecules, the bionanoparticles. Bionanoparticles are currently used as conventional vaccines, mRNA vaccines or gene therapy. These new biopharmaceuticals will satisfy an urgent medical need as they might extend the curability of to-date non-curable diseases and offer treatment for rare diseases. However, the impact of the manufacturing process for such therapies on the final product quality and consequently on product efficacy and patient safety is still not fully understood. There also is a lack of specifically trained personnel in the field of bionanoparticles.In CAARE we will develop new and intensified downstream processes and analytical tools, which are essential to obtain a pure therapeutic product and to ensure the efficacy and safety of the therapy. acib GmbH (AT), Karlsruhe Institute of Technology, University of Hamburg and University of Erlangen (all DE), Institute of Experimental Biology and Technology (PT), Leiden University Medical Centre (NL), and Icosagen (EE), seven associated industry partners, two associated universities and one regulatory agency have formed a consortium to train 14 doctoral candidates with beyond state-of-the art bioprocess and analytical skills directed for bionanoparticle purification. Latest technology of process control and monitoring for advanced bionanoparticle processing, downstream process development and particle characterization of bionanoparticles will be taught. The appropriate skills to communicate the research outcome to the scientific community and to the general public are included in the training program. We will est
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Implementation of an Integrated Care Model for Patients with Multiple Cardiometabolic and Mental Health Conditions in Sub-Saharan Africa', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Addressing multiple long-term conditions including non-communicable diseases (MLTC-NCDs) in fragile health systems in sub-Saharan African(SSA) demands a shift from fragmented models of care, that treat individual health issues separately to a more holistic integrated care  that provides a whole-person focus. However, the feasibility and effectiveness of concurrently implementing evidence-based WHO PEN and mhGAP-IG for integrated care of NCDs and common mental health problems in real primary healthcare settings remain unexplored. In addition, the adoption and implementation of the WHO PEN and mhGAP-IG strategy has been poor in the SSA, where recent analysis found the adoption and implementation to be off-track. M-CARE project therefore aims to improve primary care for patients (aged ≥18 years) with MLTC-cardiometabolic and common mental health conditions in three SSA countries (Ghana, Kenya & Uganda) by designing, deploying, and evaluating strategies for implementing the evidence-based integrated primary care model interventions that map onto WHO PEN and mhGAP-IG for PHC, taking into account diverse socioeconomic environments of these countries.The  intervention delivery will be a pragmatic trial implemented in usual primary care facilities by primary care providers through a parallel arm cluster randomized design. The trial is preceded by codesign of the integrated care with stakeholders.  This  multi-sectoral approach will increase  the capability, opportunity to improve integrated management of patients with MLTC-cardiometabolic disease and common mental health disorders in diverse SSA environments. We anticipate that the M-CARE project will lead to 35% increase in proportion of patients with MLTC-NCDs to be engaged and retained in care for effective management within
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'A Scalable QoS-enabled Business Grid Environment for Multi-User Real-time Online Interactive Applications' (2002-2006), addressing dissemination and exploitation.

assistant: **Impact**

Edutain@Grid is an exciting and ground breaking new project making use of Grid technology. The project will identify and define a new class of applications that are highly significant for Grid computing but have not been studied in the past, which we characterise as Real-Time Online Interactive Applications (ROIA). The distinctive features that make ROIA unique include large user concurrency to a single application instance, ad-hoc connections, competition-oriented Virtual Organisations, real-time interactive response, dynamically changing control and data application flows whilst maintaining high Quality of Service (QoS), user friendly security, and novel Business-to-Consumer market models. In order to overcome these challenges, the project team will develop a new middleware layer that will allow ROIA to exploit Grid computing and validate the system using two pilot applications from online gaming and e-learning domains. Edutain@Grid is expected to be of key interest to game developers and publishing companies by tackling some current key industry challenges: larger user concurrency and high QoS ranging between 64 - 128 players for fast action online games to thousand of players in persistent Massively Multi-user Online Role Playing Games (MMORPG); standard API and scalable networks for cheaper integration and online game hosting. Similarly the benefits to the e-learning community are expected to be significant where large numbers of geographically disparate students can interact with instructors making use of large operational data sets. In particular this will be relevant to online simulations in scientific modelling applications used in the energy, defence, transport and legal market sectors. Furthermore Edutain@Grid is expected to attract new developers and develop
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Transnational care practices of Brazilian Working Class Migrants living in Australia and Portugal: a comparative perspective' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

The aim of this research is to explore and compare the impact of distance on the experiences of Brazilian working class migrants living in Australia and in Portugal who care for ageing, disabled parents in their home countries. Drawing on the results of an ethnographic study of six groups of professional migrants living in Australia, conducted by Baldassar, Baldock and Witling, the research will address the questions of Brazilian migrants, motivation and capacity (ability, opportunity) to contribute to practical, emotional and personal care of their elderly parents back home, and of the structural constraints that shape the forms of this type of care-giving. By focussing on working class migrants, transnational care practices in two different countries, this research will try to shed light on the one hand on the influence that weaker levels of social, economic and cultural capital can have on the capacity and ability to provide transnational care, and on the other hand on the influence of migration and employment policies on this capacity and ability. The objectives are to develop the applicant's scientific and empirical knowledge on transnational care, family dynamics, gender dynamics and care practices; to enhance the applicant's skills of independent thinking and criticism by testing and challenging the existing theories in the field through a focus on working class migrants in two different national contexts; and to be trained to multi-sited ethnographic methods of investigation. These objectives will be achieved through the applicant's integration to the team that developed the notion of transnational care, in a dynamic process of ongoing discussion and debate; and through the transfer and application of the new knowledge and skills acquired by conducting a compara
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'NON-TOXIC AMINOPLASTIC ADHESIVE FOR MEDIUM DENSITY FIBREBOARD AND NEW APPLICATION PANEL PRODUCTS OF IMPROVED WEATHER AND BIOLOGICAL RESISTANCE', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The annual production of particleboard and medium density fibrebroad in the EU amounts to some 26 million m3, mostly bonded with urea-formaldehyde adhesives. As the adhesives cost from 20-30 % of the final product costs, they are crucial in determining profitability in a highly competitive industry. Urea-formaldehyde bonded products emit formaldehyde in service. The health effects of this substance has led to regulations limiting in emission (it must be lower than 6.5 mg/100 of board of Germany). Alternative adhesive-routes proposed were not able to solve the problems of health risk, high production cost and impaired board performance. In parallel, another problem of wood-based panels has always been their poor preservation.The main objective of this project is the development of a low to zero formaldehydeemission aminoplastic resin of improved weather an biological resistance to be used in the production of medium density fibreboard (DMF), particleboard and other wood-based panels. The synthesis route of such an adhesive, the parameters of its manufacture as well as its application conditions in panels production will be determined and optimised.The process of this project addresses all the above problems by using the followingtechniques :- copolymerization of the aminoplastic resin with long chain aliphatic primary diamines/triamines and polyamines (nylons), in order to improve the water resistance and lower the formaldehyde emission of the resin;- resin cross-linking by the use of hexamethylenetetramine in the presence of natural and synthetic colloids to further reduce the formaldehyde emission and;- incorporation in the adhesive of an easily diffusable non-toxic preservative such as boron, to improve board resistance to fungal attack.The combination of these princi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Harvesting energy via aligned porosity pyroelectrics' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Energy harvesting continues to receive increasing amounts of industrial and academic interest since it provides a route for the realisation of autonomous and self-powered low-power electronic devices. Pyroelectric materials, the focus of this proposal, are of interest since under the correct conditions they have the ability to operate with a high thermodynamic efficiency for converting temperature fluctuations into useable electrical power. To improve the power generation capability of these materials, the improvement and optimisation of the pyroelectric properties and relevant figure of merits are imperative for expanding the field of applications. In this proposal we will examine pyroelectric ceramics with tailored porosity since they have the potential to exhibit high mechanical strength and performance figures of merit by maintaining a high pyroelectric coefficient with a reduced permittivity and volume specific heat. To date, reports on the porous pyroelectric ceramics are limited due to poor control of pore size and mechanical properties. This research will focus on the development of aligned porous pyroelectric ceramics with readily adjustable pyroelectric properties. The Fellowship will allow me develop professional maturity in terms of leading knowledge transfer to a new institution, gaining experience of a boarder range of skill sets (modelling, energy, harvesting systems) for thermal energy harvesting applications. In addition, the fellowship will contribute to the strengthening of the European energy harvesting research community to the establishment of a long-term collaboration between the host and the applicant's country. By expanding my research and academic training, supported by Prof. Bowen and University of Bath, this fellowship will be a key step in t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'BioResorbable Ostheosynthesis Implant'.

assistant: **Innovation**

In the EU, 20 % of all hospital treated injuries are bone fractures. If surgical treatment of bone fractures is necessary, it is currently performed with standard metal implants. Conventional gold-standard titanium or steel implants are too stiff, have adverse effects on the patient (feeling of pain during temperature changes) and lead to stress-shielding. Their usage is associated to the risk of infections and bone loss. Often a secondary surgery for removal is needed which is associated with almost 50 % higher healthcare costs. When Mg-based implants are used they are frequently alloyed with rare earth elements, aluminium, silver or zirconium. However, zirconium reduces the healing properties, aluminium and rare earth elements may remain in the organism and can lead to unpredictable effects, while the application of silver might result in a silver-disease.Within the BRI.SCREW project we will introduce to the market revolutionary osteosynthesis implants that do not need surgical removal. We will use our own bioresorbable magnesium alloy which consists merely out of extremely high purified natural materials including Mg, Ca and Zn. BRI.SCREW is 100 % biodegradable, stimulates the healing process of the bone and has no side effects due to the implant's composition. Our orthopaedic implants will prevent the need of a second operation to remove the implant and will therefore minimize patient costs and surgical risks.Our team consists of highly qualified individuals with experience in medicine, engineering and quality assurance. The investment in BRI.SCREW will pay off. We have estimated that after 5 years from launch, we will sell in total 81.900 BRI.SCREWs (sales €13.2M), hire 10 technical employees, and manage 5% of the global market. We will earn €8.7M profit and genera
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Fusogenic-Reactor-Based Lateral Flow Assay for Extraction-free, Multiplexed Viral RNA Detection' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

In this fellowship, I will leverage recent advances in membrane-fusion-based biosensor technologies to develop an extraction-free, multiplexed lateral flow assay (LFA) for rapid, home-based viral RNA detection. The COVID-19 pandemic exposed critical limitations in virus diagnostics, with antigen-based kits lacking sensitivity and specificity, while RT-qPCR tests, though accurate, are slow, resource-intensive, and impractical for widespread deployment—highlighting the urgent need for field-deployable molecular assays that deliver reliable results. Given the coexistence of multiple respiratory viruses, multiplexed detection is also crucial. This project aims to combine my expertise in membrane-fusion-based biosensor design with Professor Dame Molly Stevens' (University of Oxford) expertise in LFA-based biosensors to create a multiplex LFA system for viral RNA detection using membrane fusion approach.  The system will first employ cell-mimetic fusogenic lipid vesicles (FusoLipo) encapsulating CRISPR toolkits, facilitating viral membrane fusion, RNA capture, and CRISPR-mediated detection. By utilizing two types of FusoLipo, the platform can simultaneously detect influenza A (H1N1) and SARS-CoV-2 without the need for complex RNA extraction, minimizing contamination risks. Once the vesicle’s cargo is applied to the LFA, catalytic nanoparticles (Nanozyme) will amplify the signal at the detection bands, increasing sensitivity. This platform ultimately provides a accurate, and user-friendly solution for home-based multiplexed viral RNA detection. Through this fellowship, I will gain access to specialized expertise and cutting-edge facilities in lipid vesicle formulation, molecular technology, LFA development, and inorganic materials synthesis in the Stevens group, alongside adva
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Supporting optimisation of photovoltaic resource efficiency and sustainability' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

With photovoltaics being expected as the main pillar of the future global energy system by 2050, understanding the underlying technological developments, their supply chain material flows, resource requirements, environmental life cycle impact and circular economy potential becomes crucial for the European continent. In the transition to an increasing electrification of the energy system, Photovoltaics gives Europe the opportunity to become independent from importing fossil fuels. With a circular economy approach – as PV technology is to almost 100% recyclable – supported by and eco design strategies, Europe has the opportunity to become less energy dependent from outside and at the same time significantly reduce the environmental impacts in its energy sector.The SOLARIS project has the expertise and is designed to give guidance and support this goal with underlying data on future market and technology development, related resource use and supply chains, environmental impact and recommendations on policy measures to guide European decision makers along this path in the future.Despite clear goals on PV deployment, support for the development of a European industrial supply chain has been minimal.SOLARIS will combine projected technology and market development scenarios from material mining to End of Life including recycling strategies for a deeper understanding of the future required material resources and waste recycling strategies throughout the whole PV value chain and analyse related environmental and social impacts and highlight opportunities for reducing the industry’s environmental impact and reduce resource criticalities.SOLARIS will also develop a database that compiles variables that contribute to GHG/CO2 and EPBT savings, which can be combined to show strategi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Ethical guidance on the use of human embryonic and fetal tissue transplantation' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

OBJECTIVES:- To ethically evaluate the practice of embryonic and fetal tissue transplantation as well as the existing guidelines and regulations of embryonic and fetal tissue tranplantation.- To make an inventory and ethical analysis of the moral issues involved.- To make a comparative analysis of existing guidelines, regulations and debates in a number of European countries.- To study empirical questions concerning the practice of fetal tissue transplantation, more in particular on:- the uses and distribution of abortuses and human fetal tissue;- attitudes and experiences of professionals involved in the handling of fetal tissue for transplantation purposes;- attitudes and experiences of women who where requested to donate fetal tissue for transplantation purposes.- To formulate recommendations, given the importance of refining and supplementing the current guidelines and regulations.BRIEF DESCRIPTION:Ongoing research in the field of human embryonic and fetal tissue transplantation (EFTT) holds promise of the development of new approaches for treatment of a variety of disorders which cause severe suffering. At the same time, however, human EFTT raises ethical questions which need to be addressed. The main goal of this project is to ethically evaluate the practice of EFTT, as well as the existing guidelines and regulations concerning EFTT. Being an interdiciplinary project, experts in the fields of biomedical sciences, law, bioethics, and philosophy participate in the project.In the first part, a comprehensive picture of the scientific state of the art and future developments in EFTT will be developed, as well as an exhaustive overview of the ethical issues raised by EFTT. Then guidelines and regulations in various European countries will be studied, as well as trans-na