RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Water resources : influence of climate change in Europe', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

RATIONALE. There are well recognised shortcomings in the communication of theoretical knowledge from climate and hydrology experts into the field of practical engineering hydrology and water resources planning. WRINCLE addresses these shortcomings by combining understanding of the underlying physical processes with an easily accessible format of 'digital atlases', custom-made for the end-user in water industries, environment agencies and government. WRINCLE aims to close the gap between the theoretical and practical aspects and to provide the sound scientific basis for regional impact assessment which to date has largely been absent. WRINCLE has the following main objectives: (a) To assess the impacts of climate change on Europe-wide water resources; (b) To use the latest atmospheric model outputs to generate climate change scenarios; (c) To present impact assessments in easily accessible 'digital atlases' for end users. Hydrological impact assessments demand a consistent methodology combining; the latest climate change scenarios, sound downscaling methods for precipitation, validated hydrological models, effective snowmelt modelling and accessible presentation of results. WRINCLE gives each area careful attention, as they are links in a chain. DELIVERABLES. The results will be produced as Europe-wide digital atlases on a 50km grid, for standard future climate projections, and will be published in hard copy, common GIS formats/ and on a World Wide Web site. The following deliverables will be produced as digital atlases; (a) Precipitation: monthly mean and number of rain days, for both regions and sites (b) River discharge and grid square runoff: monthly mean and flow duration curves (c) Water Resource impacts: drought risk, Q95, low flow statistics and HEP yields WORK C
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Non classical rarefaction shock-waves in molecularly complex vapours' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The expansion of a dilute gas through a gasdynamics convergent-divergent nozzle can occur in three different regimes, depending on the inlet and discharge conditions and on the gas: via a fully subsonic expansion, via a subsonic-supersonic or via a subsonic-supersonic-subsonic expansion embedding a compression shock wave within the divergent portion of the nozzle. I devised an exact solution procedure for computing nozzle flows of real gases, which allowed me to discover that in molecularly complex fluids eighteen additional different flow configurations are possible, each including multiple compression classical shocks as well as non classical rarefaction ones. Modern thermodynamic models indicate that these exotic regimes can possibly occur in nozzle flows of molecularly complex fluids such as hydrocarbons, siloxanes or perfluorocarbons operating close to the liquid-vapour saturation curve and critical point. The experimental observation of one only of these eighteen flow configurations would be sufficient to prove for the first time that non classical gasdynamics phenomena are indeed possible in the vapour region of a fluid with high molecular complexityTo this purpose, a modification to the blow-down wind tunnel for dense gases at Politecnico di Milano is proposed to use mixtures of siloxane fluids. Measurements are complemented by numerical simulations of the expected flow field and by state-of-the-art uncertainty quantification techniques. The distinctive feature of the proposed experiment is the adoption of mixture of siloxanes as working fluids. Mixtures of siloxanes are well known to exhibit an higher stability limit than their pure components, due to the redistribution process occurring at high temperature.The increased understanding of real-gas dynamics will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'EuroPean Training NetwoRks to TArget DAMPs and NETs: novel apprOaches in pRecision SepsIs pAtieNt care'.

assistant: **Objectives**

Sepsis remains one of the major challenges for societies worldwide, causing an estimated 7-9 million deaths every year. It is the leading cause of death at intensive care units in the EU. This high mortality persists because at present methods for timely diagnosis are lacking and no effective therapy is available. Therefore, there is a clear and urgent medical need to provide novel diagnostics and therapeutics for use in sepsis. The PRAETORIAN Doctoral Network has created a doctorate programme to deliver innovative training on preclinical and clinical science, business- and entrepreneurial aspects, intellectual properties and more, covering multiple aspects of the drug discovery and development process. This programme is unique as it will deliver a new generation of young scientists, each Doctoral Candidates (DCs), who will collaboratively work to develop novel approaches in precision sepsis patient care providing new diagnostics and therapeutics to answer to an urgent unmet clinical need. Recent insights have indicated a pivotal role for neutrophil activation and so-called damage associated patterns in the initiation and propagation of sepsis. However a comprehensive view on how these processes cause the onset of sepsis remains elusive and there is an urgent need to translate experimental findings into adequate diagnostic and therapeutic solutions. PRAETORIAN was designed to address this urgent need by bringing together specialists from academia and industry to shape a new generation of entrepreneurial scientists who have skills, expertise and knowhow to further our understanding of sepsis pathophysiology into tangible and effective solutions for novel diagnosis and therapy.


**Keywords:** Sepsis, septic shock, organ failure, NETosis, neutrophil activation, DAMPS, cli
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Measurement of haematogenous micrometastases associated with prostate cancer by RT/PCR and DNA probe detection of prostate specific antigen(PSA) mRNA' in the context of a Fourth Framework call.

assistant: **Objectives**

The aim of this research and development project is to establish a reliable, reproducible, semi-quantitative, precise and sensitive RT/PCR PSA assay, in conjunction with a state-of-the-art detection method of amplified target mRNA. PSA mRNA is exclusively transcribed by prostatic epithelial cells. The presence of such cells in the blood and/or in tissues other than the prostate gland is abnormal and can only be attributed to the spreading of prostate cancer. Hematogenous metastasis are suspected to be the carrier of prostate tumor cells to bone metastasis. The RT/PCR PSA assay will be used as a reference method to study metastasis in human prostate cancer, by evaluating the presence of circulating prostate cancer cells in peripheral blood. After RNA isolation from the specimen, the assay utilizes a reverse transcription (RT) reaction to produce PSA cDNA which will be subsequently amplified by a polymerase chain reaction (PCR). The amplified target DNA will then be captured and its presence visualized by means of an immunoassay-like detection procedure featuring homogeneous hybridization, magnetic beads separation and a chromogenic enzymatic reaction. An innovative and commercially viable RT/PCR PSA assay that can be used for 'in vitro' diagnostic tests will be developed. The final product will be a DNA-probe kit which includes the critical reagents required to perform the assay, as has been accomplished with other widely used immunodiagnostic kits. The procedure will be optimized in terms of sensitivity, specificity, practicability, cost effectiveness, total assay time, reagent presentation, negative and positive controls. The detection procedure of the amplified target DNA will offer researchers and clinicians major advantages over the currently used methods in molecul
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Formal Safety Assessment (FSA) of High Speed Craft (HSC) - Propulsion and Manoeuvring System Reliability' (FSA).

assistant: **Innovation**

Objectives and content Shipping is currently evolving from the traditional safety concept, based on compliance with prescriptive requirements, towards the so-called Formal Safety Assessment (FSA): the experience gained in other industrial fields confirms the effectiveness of this more flexible and committing risk-based approach. The objective of this proposal is to adapt and develop the methodology for application to High Speed Craft (HSC) given the particular characteristics and rapidly changing technology of this type of craft. This will include: - development of reliability, availability and vulnerability analyses specific to the specialised propulsion and manoeuvring systems; - design and creation of a quantitative database covering reliability of relevant systems, operational experience, accident/hazardous occurrence information, for risk and cost/benefit assessment purposes; - identication of impact of FSA on the existing design practice and safety regulations. The partnership involved will combine expertise of specialists in ship safety and risk assessment (BV, MSA, CETENA) with the industrial experience of a propulsion system supplier (MTU), a shipbuilder (BAZAN) and a shipoperator (DSB), all experienced in High Speed Craft and representing various maritime areas in Europe. The FSA gives a consistent framework which enables to address all the potential hazards on the whole ship Iife-cycle, in a systematic process including consideration of the human element. It is expected that through harmonized implementation of FSA and the resulting improvements in safety and reliability, competitiveness of transport by HSC will be significantly increased in terms of: - prevention of accidents, increase of commercial - availability, optimization of production and - operation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'implementAtion anD OPeration of the gateway for healTh into BBMRI-ERIC' (2014-2020).

assistant: **Concept**

BBMRI-ERIC: the Biobanking and BioMolecular resources Research Infrastructure - European Research Infrastructure Consortium, aims to establish, operate and develop a Pan-European distributed research infrastructure in order to facilitate the access to biological resources as well as facilities and to support high quality biomolecular and biomedical research. The ADOPT BBMRI-ERIC proposal aims at boosting and accelerating implementation of BBMRI-ERIC and its services.  Its main deliverables are designed to complete or launch the construction of key Common Services of the Research Infrastructure as required for ESFRI-projects ""under implementation"", reflecting the targets of the European Research Area (ERA).  One of the challenges in the post-genomic era is the research on common complex diseases, such as cancer, diabetes and Alzheimer’s disease. Revealing these diseases will depend critically on the study of human biological samples and data from large numbers of patients and healthy individuals. The EU’s ageing population is will result in an increase in many of those diseases and consequently an increased healthcare expenditure for senior citizens. BBMRI-ERIC is a specific European asset having become a fundamental component in addressing the ongoing and future requirements particularly of Europe's health service frameworks, including competitiveness and innovativeness of health-related industries. Its implementation is essential for the understanding of the diversity of human diseases, biological samples and corresponding data, which are required for the development of any new drug or diagnostic assay and are, therefore, critical for the advancement in health research, ultimately leading to personalised medicine. BBMRI-ERIC will provide a gateway access to the colle
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'European nuclear structure integrated infrastructure initiative (EURONS)' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

EURONS is the Integrated Infrastructure Initiative of the European nuclear structure scientists. Institutions from 27 countries represent the community at large and within an equal opportunity structure. It proposes a coherent and complementary ensemble of networking, transnational access and joint research project activities underpinning new European large-scale projects and commitments. Moreover, it represents a quantum leap in European Integration, where in practice the coordination level is expected to surpass those of comparable communities and sister facilities in the United States and Japan. In this spirit, EURONS builds on a successful and rich tradition of interplay between theory and experiment, and universities and large-scale infrastructures and continues collaborative European research actions which already were initiated and recognised during preceding framework programs. This optimisation of European resources will not only maintain, but even enhance the historical lead of the European nuclear structure scientists. The access to the world-class facilities UCL-CRC (B), ECT* (EUR), GANIL (F), GSI (D), CERN -ISOLDE (EUR), JYU-JYFL (FIN), RUG-KVI (NL), INFN-LNL (I) constitute the backbone of EURONS. The highly successful FP5 Infrastructure Cooperat ion Network FINUPHY will thus be intensified in order to reach a further level of quality and quantity of access. Further improvements and extensions of these facilities are the objectives of the 11 Joint Research Proposals of EURONS. The Networking Acti vities of EURONS have a more prospective character with an emphasis on fostering future cooperations, pooling of resources (including human capital), stimulating complementarity and ensuring broad dissemination of results. This includes also the activities for the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Formal Ontological foundations for Information Systems' (FOFIS) targeting Sixth Framework.

assistant: **Abstract**

Since the eighties information science has embraced the methods of philosophical ontology to represent and reason in the heterogeneous world of intelligent systems. The need for a reliable and flexible way to describe these systems has pushed toward ontological methods that guarantee a result as general as possible while remaining faithful to the things one wants to represent. Nowadays, ontologies are a crucial concept in this area and are employed at different modelling stages although, we must add, a principled methodology is still lacking. This situation is particularly evident in large domain areas where the right level of generality is hard to reach and it is the cause of many unsolved modelling problems.A typical example is the class of and quot, artefacts and quot, that is, entities ranging from concrete objects like bolts and nuts to objects characterized by their content like books, files or programs. In the case of artefacts, interoperability is of utmost importance. For that reason, a reliable and general way to make functionality explicit and to represent physical and computational features is crucial. The aim of this project is the development an ontology of artefacts that captures their functional and material aspects.The underlying view is based on the assumption that functionality is closely related to the shared context in which artefacts are used. Also, it is believed that a unifying theory concerning both works of art and technical artefacts is possible and that this approach can put it forward. In the second part of the project, the proponent aims at verifying the results of his theory by applying it to the domain of and quot; information objects and quot: books, computers files, catalogues, and so on. Indeed, information objects are at the core of i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'TASTE THE  RESEARCHERS’ LIFE' to be submitted under Seventh Framework.

assistant: **Abstract**

The main idea of TRAiL (Taste the ReseArchers’ Life) is to show that researchers are human beings belonging to one big research family integrated in the European society. The project is a trip of imagination and scientific rigor to understand what attracts to pursue a scientific career and why a young should choose to be a researcher through events that show how researchers feel the world around them. TRAiL would like to be a path to tackle the stereotypes about researchers via a variety of events in direct contact with the general public, showing their real face and enhancing the researchers’ role inside society.The project is articulated in harmonically and well-equilibrated informal, pleasant, enjoyable and attractive activities linked with science. Several edutainment activities and events addressed to the public at large will be organized with researchers being actively involved and directly in contact with the visitors in order to: promote the European dimension of researchers, valorise the job researcher, enhance researchers’ integration, reinforce the link between researchers and citizens and promote scientific careers among young people.The TRAiL project is organized by researchers and citizen of Frascati Scienza association, and is hosted in the largest research area in Italy where more than 3000 international researchers live and work. The event will be performed and hosted in the laboratories of the most important Italian institutions ASI, CNR, ENEA, ESA-ESRIN, INAF, INFN and INGV located in the south of Rome, the three Universities of Rome Sapienza, Tor Vergata and Roma Tre, the European Gravitational Observatory in Pisa and the Gran Sasso Laboratory of INFN.Frascati Scienza is supported in the project from many local, regional and national institutions and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Descriptive Complexity of Infinite Domain Constraint Satisfaction Problems' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The constraint satisfaction problem (CSP) is a computational problem where the instance consists of a finite set of variables and a finite set of constraints, and the goal is to decide if there is a mapping from the variables to elements of some fixed domain of values satisfying all the constraints. Such problems are ubiquitous in different areas of computer science, including artificial intelligence, scheduling, computational linguistics, computational biology, and combinatorial optimisation. InfCSP will use mathematical tools to study the descriptive complexity of infinite domain constraint satisfaction problems.The main purpose of InfCSP is to understand the power of generic logic-based algorithms for CSPs with infinite domains of values. More precisely, we will analyse the class of CSPs parametrised by the type of constraints allowed in the instance in order to determine for which problems in this class the set of YES instances can be captured by a logical formula. The logics of interest will be Datalog and the first-order logic extended by a fixed-point operator, widely studied in the context of constraint satisfaction. The classifications will be obtained using methods from descriptive complexity, universal algebra and model theory. InfCSP will constitute a major step forward in understanding which infinite domain CSPs can be solved in polynomial time and developing new universal-algebraic tools for infinite domain CSP.


**Keywords:** Infinite Domain Constraint Satisfaction Problem, Descriptive Complexity, Datalog, Fixed Point Logic, Universal Algebra