RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Regulatory Logic, Thresholds and Epigenetic Memory:  How cis-regulatory landscapes tune gene activity during mammalian development' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Development of multicellular organisms relies on differential gene activation in a single genome. In response to multiple quantitative signals, cell-type specific transcriptional programs are established that determine cell identify. Their perturbation can result in pathologies such as cancer. Large cis-regulatory landscapes integrate information on cell state, space and time to precisely tune the activity of developmental genes. How cis-regulatory landscapes decode multiple quantitative signals remains poorly understood. CisTune aims at gaining a functional and mechanistic understanding of how regulator levels are sensed, how the input from multiple regulators is integrated and how information is processed by cis-regulatory landscapes.CisTune will use the Xist locus as a model, which controls X-chromosome inactivation, an essential developmental process in mammals. Xist's cis-regulatory landscape integrates multiple quantitative input signals that transmit information on sex and developmental time, to ensure up-regulation from one X chromosome in each female cell. In CisTune we will thus study an essential process in great depth to identify regulatory principles that control activity of the mammalian genome during development.CisTune will use an interdisciplinary approach at the intersection of systems biology, epigenetics and gene regulation, where highly multiplexed perturbation experiments of endogenous genes are interpreted with the help of mathematical models. We will build on recent technological breakthroughs, including single-cell genomics and high-throughput CRISPR screens, which we will complement with a new approach to functionally link sequence elements to their input signals. CisTune has the potential to overcome challenges that have prevented mammalian qu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Exposure To electromAgnetic fIelds and plaNetary health' (ETAIN), addressing dissemination and exploitation.

assistant: **Impact**

The ongoing introduction of new telecommunication technologies (5G now, 6G next) comes with changes in exposure patterns and of biological interaction with humans and ecosystems. E.g., the coming mm-wave technology will lead to higher dose in human skin and eyes and higher absorption in small bodies, like insects. It is unclear if these changes are accompanied by adverse effects and what it means for current exposure limit regulation.ETAIN aims to develop and validate approaches to assess the impact of existing and novel communication technology from a planetary health perspective, while exploring options for exposure reduction and interacting with the public and stakeholders about exposure levels and possible associated risks. Following a citizen science paradigm, we will develop an app able to quantify personal absorbed RF-EMF. The app data allows to calculate realistic personal and population dose distributions including RF-EMF maps; and it will ensure a communication strategy matching knowledge needs of citizens and stakeholders. Insights into own exposure and its major contributors will empower citizens to manage their RF-EMF exposure. Also, ETAIN will develop and validate network architecture approaches for an “ALARA by design” approach.ETAIN will elucidate underlying mechanisms of biological effects in humans and the environment. We will focus on human skin and eyes as relevant biological targets of 5G and beyond, and a systems biology approach to evaluate possible effects. Additional efforts focus on insect biodiversity and fitness, especially pollinators at risk of peak exposures close to strong antennas, such as bees. From a planetary health perspective, RF-EMF effects on insects may also have indirect effects on human health and the economy (e.g. via pollinat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project ''New Images of Man'? Remaking Art in Postwar France, 1944–1968' (REMAKING) under Horizon Europe.

assistant: **Objectives**

This project is designed to address the longstanding masculinist interpretation of visual art in the decades immediately following the WWII in Europe. Since the 1950s, the aesthetics of art in this period  of rough surfaces, violence, and gestural grandeur  has been interpreted in essentially masculine terms as interrogating man. Yet women sculptors and painters were among the most important artistic innovators shaping new directions for European modern art. This project examines how women artists in this period shaped new artistic practices and artistic identities in a transformed postwar environment. By developing new multidisciplinary historical and theoretical frameworks that combine feminist, queer, and ecological approaches, it seeks to forge a new interpretation of postwar art-making that no longer perpetuates the myth of the lone male hero.The project will be undertaken under under the supervision of Elissa Mailnder, at the Sciences Po Centre for History (CHSP), whose connections, experience, and research expertise on gender, violence, and WWII, are acutely relevant. The CHSP will also offer expert interlocutors for the project including world-leading art historian on post-WWII France, Laurence Bertrand Dorlac. Since my aim is to help change widespread cultural perceptions, a key project objective is to communicate results widely. I will produce open-access research articles, an online essay, an exhibition, a major conference open to the public, and an eventual monograph. Building on current public interest in modern women artists, and my proven communication skills, most outputs will be relevant to both public and scientific audiences. The action is also designed to strengthen a range of research and transferable skills, and to reinforce the interdisciplinarity
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'European Lighthouse of AI for Sustainability' under Horizon Europe.

assistant: **Concept**

We live in a crucial historical moment, with tremendous challenges ahead, from climate change to the energy crisis. ELIAS emerges from the belief that AI will be a key discipline to help us tackle these challenges. At the same time, the development of AI entails deep ethical and societal concerns that need to be addressed. As for fundamental research, ELIAS will address key scientific questions about how AI can reduce computational costs, serves to model effects of policy decisions on society, and impacts individuals. ELIAS will strive for a deep integration of the fundamental research that takes place in academia and the more applications-focused research from industry. ELIAS builds on and expands the highly successful and internationally recognized EuropeanLaboratory for Learning and Intelligent Systems (ELLIS). ELIAS will further develop the excellence criteria and the pillars in ELLIS and implement actions that will support AI researchers and young talents at different stages of their careers.  Furthermore, ELIAS will develop a Sciencentrepreneurship track, with the purpose of attracting and empowering talents at the interface of scientific innovation and business and establish original AI solutions that move towards a sustainable long-term future for our planet, contribute to a cohesive society, and respect individual rights. The outcome of ELIAS will be to establish Europe as a leader in AI research in which impact on the environment, society and the individual are integral considerations during development. We will measure the success of this endeavor in terms of key indicators, including the number of new cross-institutional collaborations, the number of cross-disciplinary collaborations, the number of industry-academic partnerships, publications in top conferen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'GoPhoton! - Photonics for everyone'.

assistant: **Innovation**

The mission of this project is to make a significant contribution to raising awareness about the importance of Photonics, aiming at having impact on young minds, entrepreneurs and society as a whole. GoPhoton! aims to transmit a critical message across Europe: Photonics is ubiquitous and pervasive, it is a key enabler of the European economy and job creation, and it offers outstanding career and business opportunities. The project intends to address these challenges through a series of actions that will be developed through a collaborative network, the European Centres for Outreach in Photonics (ECOP), an alliance committed to creating durable long-term partnerships for enhanced engagement in Photonics outreach. The project aims at strongly involving the relevant European stakeholders, seeking synergies with Photonics 21, the industrial clusters and educational networks, and a possible International Year of Light in 2015. The existing tight links of the project partners with the local educational networks (teachers and science museums) will be extensively used and amplified to engage youth. Communication specialists and media will play a critical role as multipliers of the message to make Photonics a household word and to reach out the general public.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Dam-nations? A study on dams, nation-building and transboundary water relations through case-studies from Ethiopia and Tajikistan' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The aim of DAM-NET is to enable the Future Fellow (FF) to carry out a state-of the art research project, investigating how ruling elites can use the symbolic value of a large hydraulic infrastructure to construct and disseminate their particular idea of the nation and legitimize their hold on power. The study will expand on the largely unexplored link between water and social power, bringing new insights into the analysis of transboundary water relations and on the role that discourse and nationalism play in water politics. Throughout a varied set of activities, the project will allow transfer of knowledge and the training of the FF, thus improving his employability and career perspectives.Interdisciplinary in nature, DAM-NET will draw upon insights from International Relations (IR), nationalism studies and political geography to create a framework for the analysis of the politics of mega-dams. Specifically, two case studies – the Grand Ethiopian Renaissance Dam (GERD) in Ethiopia and the Rogun Dam (RD) in Tajikistan – will serve as a platform to analyse the discursive constructions surrounding mega-dams, and to map and unpack stakeholder and elite networks associated with the water sector in both countries.Besides their scholarly relevance, the research findings will provide important policy insights for a better understanding of the new boom in global dam building, and for the explanation of seemingly irreparable regional conflicts triggered by the construction of extremely costly megaprojects.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Embedded systems technologies' (EMTECH).

assistant: **Innovation**

EMTECH aims at improving development and take-up of technologies in the field of embedded systems, in particular by SMEs. EMTECH will specifically groups not currently present in the Framework Programme and focus on topical sub-areas such as the automotive industries. EMTECH will increase our understanding of the SME potential in the area by analysing strengths, weaknesses, opportunities and threats.The EMTECH method is based on dynamically expanding a network of project participants to quickly reach critical mass in Europe. It will base its specific activities on a careful analysis of the situation and on input from additional experts. Thus the project will be acting as a catalyst for improving the co-operation of SMEs with both industry and academia. The project will also create additional visibility and impact for running projects in creating and supporting relevant PR so as to facilitate the dissemination, transfer, and exploitation of past and present programme results.EMTECH will further the participation of SMEs in Embedded Systems research and technology development projects at a European level. It will promote improved tools for partner search in this field and generally increase the understanding of SMEs in this area. As a side effect, EMTECH will improve the visibility of research activities, PR and public understanding of ES RTD together with significant gains in technology diffusion and promotion of research results to a wider audience.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Moulding of wood-based composites' in the context of a Fourth Framework call.

assistant: **Objectives**

The proposed project will develop a material, a manufacturing process, and a prototype equipment to produce consumer articles and industrial products normally made by wood carving or plastic injection moulding. Examples are furniture parts, clog soles and building components. The material developed is a wood-based composite, and one of the challenges in the RTD-work is to develop a composite with only a small content of bonding substance, still maintaining a strong and ductile material. Other challenges are to develop a range of process parameters, a set of tooling and a machine which can form a basis for subsequent industrial production. The proposing partners are a Danish toolmaker and a Swedish designer and manufacturer of plastic parts. The proposers have already identified two potential RTD performers, although they are still conscious that the consortium requires some additional partners in order to be geared ideally for the project. It is suggested that the exploratory phase encompasses both a rather comprehensive research feasibility study to establish a solid project baseline and a proposal expansion.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'GUIDELINES IN HEALTHCARE' to be submitted under Fourth Framework.

assistant: **Abstract**

PRESTIGE is to introduce telematics applications for faster implementation of new standards of best practice in Europe. By these techniques it will assist in the generation, dissemination and routine application of guidelines and bridge the time lag between research and everyday clinical practice. The project will include heart and nervous diseases, diabetes and general practice, mobilising substantial user involvement through national and specialist user groups.There is a wide consensus between healthcare professionals that unacceptable delays occur in the implementation of new standards for 'best practice'. This problem is common to the everyday practice of healthcare professionals throughout Europe and results in poor quality of care and wasted resources. PRESTIGE addresses this problem by the use of clinical guidelines and protocols which have been shown to be effective in improving the healthcare process in terms of quality, efficiency and outcome. The project will use healthcare telematics technology to assist in the generation, dissemination and routine application of guidelines, and thus will bridge the gap between medical research and everyday clinical practice. To support the use of clinical guidelines and protocols, PRESTIGE will verify and pilot a set of integrated technologies that build on experience and expertise gained during the 1991-1994 AIM programme together with other leading European professional, governmental, clinical, industrial and specialist participants.PRESTIGE is structured into several actions addressing major healthcare specialties including cardiothoracic disease, neurological disease, diabetes and general practice. Substantial user involvement has been assured through national and specialist user groups and renowned healthcare centres.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Metabolic regulation of mitochondrial morphology' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The need for mitochondria in the body is ubiquitous yet the shapes these organelles take vary widely across tissues and change rapidly in response to nutrient availability.  How and why this occurs is not well understood.  Therefore, we propose an interdisciplinary research program that will investigate the molecular basis and metabolic regulation of mitochondrial morphology. Mitochondrial morphology is defined by opposing events of fission and fusion, which must be tightly controlled. We discovered that accelerated mitochondrial fission impairs cardiac metabolism and causes heart failure in mice, revealing an intriguing link between mitochondrial dynamics and metabolism.  Seeking to understand how metabolic signals drive mitochondrial fission, we will characterize the inner membrane protein MTP18, whose fission activity is controlled by the PI3K nutrient-signalling pathway.  First, we will define the interactome of MTP18 to discover the molecular components of the inner membrane fission machinery. Second, we will investigate the how mitochondrial fission is regulated by PI3K nutrient-signalling pathway the heart, liver, and kidney.  We will determine whether cardiac dysfunction, liver cancer, and kidney failure caused by over-active PI3K signalling in the mouse can be rescued by blunting the downstream activity of MTP18 and re-balancing mitochondrial dynamics.  Third, we will determine the disease relevance of mitochondrial fission in humans.  For the first time, mitochondrial morphology from patient-derived cells will be evaluated in automated, high content screens to identify human mutations that drive imbalanced mitochondrial dynamics in a truly unbiased manner. Genome-wide RNAi screens in these cells will reveal novel modulators of mitochondrial dynamics.  Taken to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Materials irradiation: from basics to applications' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Quite frequently matter is subject to irradiation. One can think of electronic devices in space, radiotherapies, materials processing by sputtering, nanoparticle modification, materials in the civil nuclear industry, radiation detectors, and many others. There is a common denominator to these scenarios, and is that radiation brings matter out of equilibrium, sometimes quite dramatically as in laser ablation, leading to a variety of physical, chemical, and biological phenomena at all scales, starting at the attosecond and nanometer with electronic excitation, and going up to meters and days or even years at the engineering or biological scale, where macroscopic phenomena like failure, fracture, explosion, or death can occur as a consequence of irradiation. Sometimes the goal is to avoid or mitigate damage, and other times is to harness the effects of radiation to alter the properties of materials. In all these scenarios it is crucial to understand the fundamental mechanisms of material response to intense and fast energy deposition.The research aim of MAMBA is to advance our understanding of material response to irradiation and to apply it to tailor and control the properties of materials exposed, purposedly or involuntarily, to intense radiation environments. We have selected five case studies lying at the frontier of knowledge, and spanning applications in diverse, although connected, fields: space electronics, photovoltaic cells for space applications, radiation-resistant nanostructures for nuclear fusion applications, radiation detectors for clinical studies, proton radiotherapy, and radiolytic hydrogen generation in nuclear decommissioning. These topics will be addressed through a combination of experimental and modelling techniques that, to a large degree, are comm