RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Training on Advanced Stem Cell Technologies in Neurology' in the context of a Horizon 2020 call.

assistant: **Objectives**

Neuronal disorders (NDs) are associated with behavioural and cognitive impairments and have a high prevalence. As such they are a high emotional, financial and social burden on the patients and their social network. To reduce the impact of NDs new scientific technologies and disease models must be developed, and specialized professionals are needed. The primary aim of ASCTN-Training is to provide the appropriate training for the participating ESRs, so that each individual ESR will complete a PhD degree based on their research work, while at the same time equipping them with the necessary tools to collaborate and develop innovative technologies for the modeling of NDs and the development of novel therapiesASCTN-Training consists of six closely interlinked Work Packages (WPs), the central theme – techniques for modeling neuronal disorders - will be executed through scientific WPs 1-3 – biotechnology, molecular neurobiology and preclinical studies - where individual ESRs will be trained together across multiple scientific disciplines. Training will be achieved using the different didactic methods in WP4 – education and training - to enable efficient work on each ESR project as well as in joint efforts with other ESRs both within and across WPs1-3. Each ESR project is directly or indirectly linked to other ESR projects and contributes various parts to the different scientific WPs, which in turn will make a large contribution to the completion of the scientific deliverables. The education, training and industrial secondments will provide ESRs with training in both individual scientific disciplines and inter-disciplinary fields. This approach will provide ESRs with the transferrable inter-sectorial skills and tools that will prepare them for innovative thinking and true inter
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Non-Invasive Technology for Intracranial Pressure (ICP) Measurement' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Elevated IntraCranial Pressure (ICP) is a critical condition derived from diseases or brain trauma. If not treat promptlyelevated ICP can cause severe damage on the brain or even death. The gold-standard method to monitor ICP is an invasiveand highly complex procedure, which requires drilling a hole in the cranium and proper insertion of catheters in the brainventricles, exposing the patients to high risk of complications, such as infections and haemorrhage. Due to the highcomplexity of the procedure and need of expertise, it is very often applied too late, hampering early diagnosis and successfultreatments. StatuManu has developed the first non-invasive method to measure variations of ICP with adequate accuracyand precision to be accepted in clinical practices. It is a very user-friendly procedure, consisting of recording a video of theeye fundus by off-the-shelf fundus cameras and further analysis by our software (cloud-based) hosting our unique algorithmcapable to deliver a result in less than 1min.StatuManu software will greatly benefit: 1) Healthcare professionals (end-users) by having a decision support tool based onearly and accurate assessment of ICP variations, 2) healthcare institutions (customers) by improving services workflow andphysicians decision making, saving costs and offering higher quality care; 3) patients by having access to a faster, accurateand non-invasive assessment (anytime, anywhere, whenever needed), and consequently early treatments.ICPstatu project will enable the development of a comprehensive business plan, including a business model compatible withmarket expansion and growth. We are supported by clinical development partners and our team has the right combination ofexpertise in image analysis, deep learning, software development and bus
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how '“The Emergence of Autonomist Politics: European Radicalism after the Extreme Left, 1976-1985” (AutPo)' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

“The Emergence of Autonomist Politics: European Radicalism after the Extreme Left, 1976-1985” (AutPo)AbstractThis project will produce an original, comparative, and transnational study of the European autonomist movements of the late 1970s and 1980s, the most significant youth movement in the contemporary history of Western Europe after that of 1968. The study will focus on autonomist currents in the major metropolitan centers of Paris, Milan, Rome, Zurich, Frankfurt, and West Berlin, focusing particularly on autonomist ideologies and practices and the response of institutions, including the far left, radical feminist movements, and the state, and on examining issues of protest and political violence. The objectives of the project will be achieved by archival research in both state and social movement archives in France, West Germany, Switzerland, and Italy, including a secondment in Rome, but will also be amplified by the constitution of an oral history interview base and the use of questionnaires informed by the most recent sociological methods. The study is relevant to the MSC-IF program because of the enduring impact of autonomism on radical political culture in Europe and because it will examine dynamics of political violence in protest movements, moving beyond the typical focus of studies of violence in the 1970s on terrorism and armed movements. In so doing, it will facilitate better understanding of the dynamics of violence in contemporary protest by helping to identify the historical transformations of protest cultures and the interactions between protest movements and state institutions in a comparative and transnational lens focused on recent European history.


**Keywords:** Autonomism, political radicalization, protest, violence, governance, 1977, transnati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'PHA production from sugar cane derivatives' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

The main objectives are defined as follows :* To develop a fermentation process for the production of biodegradable PHAs (polyhydroxyalkanoates) from cheap renewable substrates employing a previously isolated bacterial strain and agroindustrial products.* To initiate a screening program to detect and isolate new bacterial strains with the capabilities to produce PHAs with different properties for future applications from renewable substrates.* To conduct basic studies on the biochemistry and genetics of PHA granules associated proteins in the bacterial strains mentioned above.Expected OutcomeThis project should reveal a process for production of PHA at low costs. The proposed research will also enhance the research level and the training of human resources in the participating developing countries. This will be achieved not only by an extended exchange of information and knowledge between the participating laboratories, and by the provision of strains and genes, but also and in particular by increasing the mobility of researchers of all participating laboratories as a result of giving researchers (PostDocs) or Ph. D. students of the laboratories of the developing countries the possibility to visit the laboratories of the other partners and to learn sophisticated methods. Vice versa, researchers from the latter laboratories will visit the participating laboratories of the developing countries for training courses and for laboratory research.The key activities involve:* Employ batch cultures in stirred tank reactors for growth of bacterial cells on sucrose to high cell densities with maximum PHA content. The feeding regime, temperature, agitation, aeration rate, pH, medium components, dissolved oxygen concentration will be optimized for this purpose.* Proteins associated
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'A pharmacogenomic approach to coumarin anticoagulant therapy'.

assistant: **Innovation**

The effectiveness of treatment with oral anticoagulants in the prevention of thrombotic disorders is well established, but these drugs are potentially dangerous because of their narrow therapeutic index. In Europe three coumarins are used: warfarin, acenocoumarol, and phenprocoumon. Genetic factors that have been recently demonstrated to change the pharmacokinetics and pharmacodynamics of coumarins are the presence of polymorphisms in the genes encoding for CYP2C9  and VKOR (vitamin K epoxide reductase complex). Polymorphisms in these genes are associated with increased risk for severe overanticoagulation and bleedings. A clinical trial will be performed in seven European countries to determine whether knowledge of the genotype of patients at the start of coumarin treatment will increase the safety of use of these compounds and whether such gene testing is cost-effective. Patients will be randomized to receive treatment with a coumarin either dosed with an algorithm that does not include information on their genotype, or with an algorithm that does contain this information. The primary outcome will be time within therapeutic INR range. Secondary outcomes include INR>4 and bleedings.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Coenzyme A – Launch of In Vivo Experiments' in the context of a Horizon 2020 call.

assistant: **Objectives**

Acies Bio is looking to hire an expert on disease model development – particularly whole organism models in fruit flies – to join our drug discovery team developing 4-phosphopantetheine-related compounds for treating a range of Coenzyme A (CoA) metabolism related pathologies. Acies Bio’s lead compound is able to directly manipulate cellular CoA levels, which addresses the common underlying cause of this class of diseases. High therapeutic potential of this innovative treatment has been demonstrated for pantothenate-kinase-associated neurodegeneration (PKAN) and has resulted in the European Medicines Agency granting our lead compound orphan medicinal product designation. Application of this class of compounds to related diseases forms a core part of our Innovation Strategy, and could have far reaching implications in diverse areas such as numerous rare metabolic diseases, Alzheimer's disease and diabetes. This would not only make treatment available to a wider population of patients, suffering from currently untreatable conditions, but also open new opportunities for Acies Bio. Despite being world leaders in the field of CoA metabolism, as evidenced by our contribution to the TIRCON consortium, prior recruitment of relevant expertise has been hindered by obstacles within the national labour market. Hence, this call affords a valuable opportunity to recruit an Innovation Associate, to evaluate existing models in fruit flies, develop new disease models, implement novel phenotypic assays, and lead a dedicated facility. Acies Bio will provide outstanding coordination and support facilities, state-of-the-art chemical synthesis and analytics laboratory and a research-driven, commercial environment. Successful completion of this crucial step for proof-of-concept in alternative
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Warwick Economics Marie Curie Host Fellowships' under Sixth Framework.

assistant: **Concept**

The proposal is to support SEVEN students to undertake Research training in Economics at the University of Warwick. Each student will undertake a 3-year programme of coursework and supervisedresearch. The Department of Economics at the University of Warwick is one of the very largest research training centres for Economics in the UK. We have approximately 40 full-time academic teaching staff and around 50 PhD students at any one time. We take on about 12 new PhD students every year. In addition we have a significant number of purely research staff- mostly young research fellows and research assistants attached to specific projects. The Department is part of a large Social Science faculty, whichs also of high quality and we also have strong links with the Warwick Business School and cognate departments such as Mathematics and Psychology outside of the faculty. The department is strongly embedded in a multidisciplinary environment that our students benefit from considerably. The Department has an outstanding international reputation for research in several areas of economics, including microeconomic theory, macroeconomics, industrial economics, labour economics, public economics, applied and theoretical econometrics and economic history. It is one of only four UK economics departments to achieve the maximum 5 rating in the most recent (2001) national Research Assessment Exercise. Only 3 other departments in the UK have thisdistinction. The department offers a number of undergraduate degree programmes, and taught Masters programmes in Economics, Economic Analysis and Policy, and Economics and Finance. It also has a thriving PhD programme with around 50 research students. It was awarded the maximum possible rating of 24/24 in the recent national Q Subject Review (2001). Th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Templates for engineered nano-objects for use in microwave, electronic devices and biomedical sensing applications' (NANOTEMPLATES).

assistant: **Innovation**

NanoTemplates STREPS project will push the Frontiers of Science of a unique range of nano- objects made by further extending nanotechnology developed in two EU RTD projects [NanoPTMS & GMR - BE95-1761 & NanoPTT - G5RD -CT1999-00135]. It will seek a dvantageous property discontinuities arising from the nano-regime and explore these through a range of novel nano-systems to identify promising areas for further development. The project will be underpinned by IPR from previous EC projects employing UCL te chnology based on heavy ion bombardment and track etching of polymers for nano-object fabrication. Fundamental studies of the track etching and patterning processes will be made. Nanoporous substrates (pores down to 10nm), polymeric and metallic nanowires and nanotubes in various forms (Nano-objects), including particulate and embedded within coatings and self-supporting films, will be developed (UCL, Epigem, CNRS). Alternative route to nanoporous arrays will also be investigated by using AFM tip generation of pores (CNRS) in spin-coated films. The characterisation of the nano-objects will be performed and specific properties will be measured. It is intended to screen optical, magnetic and chemical properties. The response of magnetic metallic nanowire array s to high frequency fields will be investigated (Thales, UCL), whilst CRF and Thales will explore the magnetic properties of the nano-structures. Spin dependent phenomena in magnetic nano-objects will be investigated by UCL and CNRS to explore ultimate lim its of magnetoresistive effects and potential long- term applications to quantum computing. UNEW and Epigem will integrate nano-objects in microfluid nanosystems and measure biomedical properties. CRF and Durham will explore nano-objects in the form of li ght sources
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'THE INTERMODAL BIKE - Multi-modal integration of cycling mobility through product and process innovations in bicycle design'.

assistant: **Objectives**

Goals • Object of this work is to provide -by means of product and process innovations- an advanced compactable bicycle, making it practical to carry along a bicycle aboard public transportation, easily, safely and for a large number of passengers. The ultimate goal is a synergic, intermodal integration of public transport and cycling, expanding the share of both modalities in the urban mobility. Drivers • Bicycling, very efficient in the short range, but not so on longer distances, could be re-introduced into daily travel to handle the trip’s end portions, enhancing the effectiveness of other modalities through an additive effect, re-balancing in a cost-effective way the modal mix in favor of micro-mobility and public transport. The state of the art doesn’t allow a collective, pervasive use of the folding bikes in “intermodal duty”, because of excessive weight and volume when collapsed -often exceeding the baggage limits of city bus and metros- discouraging their use out of practicality and safety on board. • The proposed research aims at providing a solution developing a fully engineered, production-ready, new bike typology, based on an innovative concept for a bike frame already tested on mock-ups and working models. The advantage over the state of the art is an unprecedented compactness (factor 6 over common folders) and low weight (factor 3) obtained combining a collapsible, pre-tensioned space-frame with a modern industrial process centered on the use of contemporary engineering plastics. The process innovation will also allow low cost, quality control, opening-closing automation, electric power assistance and last, but not least in a design-conscious world, aestethic value. The work program will develop a new supply-chain, assembling several application-specific
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'City Logistics in Living Laboratories' in the context of a Horizon 2020 call.

assistant: **Objectives**

Goods, waste and service trips in urban areas impose negative traffic and environmental impacts, and there is a need for further roll-out of cost-effective and sustainable solutions. The CITYLAB objective is to develop knowledge and solutions that result in roll-out, up-scaling and further implementation of cost effective strategies, measures and tools for emission free city logistics in urban centres by 2030. The project focuses on four axes for intervention due to their present and future relevance and impact related to topic MG-5.2 objectives: 1) Highly fragmented last-mile deliveries in city centres; 2) Large freight attractors and public administrations; 3) Urban waste, return trips and recycling; 4) Logistics facilities and warehouses. CITYLAB will i) improve basic knowledge and understanding on areas of freight distribution and service trips in urban areas that have received too little attention; ii) test and implement 7 innovative solutions that are promising in terms of impact on traffic, externalities and business profitability and have a high potential for future growth; and iii) provide a platform for replication and spreading supported solutions. The core of CITYLAB is a set of living laboratories, where cities work as contexts for innovation and implementation processes for public and private measures contributing to increased efficiency and sustainable urban logistics. Linkages will be established between the different living labs for exchange of experiences and to develop methodologies for transfer of implementations between cities and between companies. This process will be supported by a strong research team. The outputs from the living labs will include best practice guidance on innovative approaches and how to replicate them. CITYLAB will lay the gro