RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Unveiling novel metabolite-driven signalling pathways that regulate carbon/nitrogen imbalance associated to plant stress' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Environmental stresses trigger metabolic changes that alter the internal carbon/nitrogen (C/N) balance in plants to promote tolerance at the expense of growth. However, the metabolic and genetic components involved in the precise coordination of the nutritional status remain largely unknown. MetaboSignals aim is elucidating novel signalling mechanisms governing nutrient balance by using C/N stress conditions as a proxy. This 3-year project proposes the integration of molecular genetics and biological chemistry disciplines to identify signalling functions of intermediate metabolites derived from C and N metabolism and characterize new nutritional sensors of C/N balance. Here, several innovative and powerful methods for chemical distribution mapping, proteomics and transcriptomic analyses are integrated in a convergent workflow with gene functional characterization to be carried out in cutting-edge institutions such as University of California San Diego and Universidad Politcnica de Madrid. Implementation of this multidisciplinary proposal will greatly bolster the fellows scientific profile and will uncover novel metabolite-controlled signalling pathways useful for knowledge-based improvements on plant nutrition and crop yield of scientific and societal relevance.


**Keywords:** carbon, nitrogen stress,  nutritional imbalance,  sugar signalling,  intermediate metabolites,  DELLA proteins,  seedling stablishment
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'TreatPolyQ – Industrial Academic Initial Training Network towards treatment of Polyglutamine Diseases' (TREATPOLYQ) targeting Seventh Framework.

assistant: **Abstract**

Protein aggregation is a hallmark of many late onset neurodegenerative disorders including Parkinson’s Disease (PD), Alzheimer’s Disease (AD), amyotrophic lateral sclerosis (ALS), prion diseases as well as the group of polyglutamine diseases (polyQ). The aim of this proposal is to create a network of European partners bridging important basic mechanisms involved in proteinopathies, research of model diseases and treatment approaches. The “TreatPolyQ” network will focus on two main representatives of the polyQ diseases: Huntington’s disease as the most common polyQ disease as well as spinocerebellar ataxia type 3 (SCA3) as the most frequent autosomal-dominantly inherited ataxia. Patients suffer from a multitude of neurological symptoms including movement abnormalities with late onset and in a progressive manner. Up to now, no treatment or cure is available. The network will be consisting of a rare combination of experts from basic and translational research, including a Nobel prize laureate, four industrial partners (two medium, and two small companies, all incorporated as full participants) and academic leaders of the field. The network not only focuses on one special aspect of a disease but spans several important disease-associated mechanism as well as promising treatment strategies for HD and SCA3 (protein transport, protein folding, protein degradation via both the ubiquitin-proteasome system and autophagy), likely to be important across a range of neurodegenerative diseases. In order to implement these research projects, extensive collaborations and temporarily personnel secondments of the involved researchers will take place, enhancing interdisciplinary transfer of knowledge. Beyond the personalized local training plan for each employed researcher within the Netwo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Perceiving the intentions of the weakest link: How attributed individual and collective goals impact reactions to low performers in groups', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Group work has become increasingly important for many tasks and services in organisations, and organisations thus depend on successful team function. The entire group’s performance may depend on the lowest performer (weakest link), but groups’ reactions to low performers are not well understood. We suggest that goal attributions are a neglected but potentially powerful factor: Did the low performer try to outperform others (individual goal) or contribute to the group (collective goal)? In the next step, groups should evaluate whether low performers were trying to succeed (but had insufficient abilities) or were not trying (i.e., had low goal commitment). Failing despite trying will lead to excluding competitive low performers (individual goal) but lead to training cooperative low performers (collective goal). Vice-versa, lack of commitment to the collective goal to cooperate should lead to exclusion, but in attempts to change the individual goal of a competitive low performer (socialisation). These hypotheses will be tested in a series of four experiments to attain the objectives of complementing Dr. Thürmer’s skillset in (1) small group theory, (2) small group laboratory experiments, (3) transformative multilevel statistics, and (4) to advance the translational transfer to organizational settings. Publications in leading peer-reviewed scientific journals will disseminate the research results widely. The proposed action will open up the immediate career opportunity to establish his independent research group, will substantially advance his research program, and is a crucial step towards becoming a full professor in Germany. Acquired start-up funding enables extensive pre-testing and will ensure the success of this action. This trans-disciplinary research project will co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Sex-biased genome and transcriptome evolution in mammals'.

assistant: **Objectives**

Mammalian males and females have many phenotypic differences. These differences, collectively referred to as sexual dimorphism, are the consequence of natural and sexual selection for phenotypic traits that affect the fitness of each sex and are encoded in the genome. Part of the underlying genomic differences between the sexes are found on sex specific (the Y) or sex biased chromosomes (the X), while many sexually dimorphic traits probably result from autosomal gene expression differences in sex specific or somatic tissues. However, the origin and evolution of sex-biased genes in mammals has not been studied in detail. I propose to generate the first detailed qualitative and quantitative transcriptome data using next generation sequencing technologies for a unique collection of germline and somatic tissues from representatives of all major mammalian lineages: placental mammals, marsupials, and the egg-laying monotremes. Together with detailed transcriptome data from birds (the evolutionary sister lineage), complementary experiments (e.g. methylome analyses), and available genomic resources from these species, these unprecedented data will allow an integrated analysis of the origin and functional evolution of mammalian sex chromosomes, the emergence of new sex biased genes, and the evolution of gene expression in germline versus somatic tissues in mammals at large. The proposed work will thus substantially increase our power to understand how mammalian genomes evolved the capacity to produce such pronounced sexually dimorphic traits. Beyond research pertaining to sex biased genome evolution, our data will represent a unique resource for future investigations of mammalian gene functions and serve as a basis for exploring the evolution of other mammal specific phenotypes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Substitution of synthetic sweeteners through stevia rebaudiana bertoni'.

assistant: **Concept**

Stevia rebaudiana is a new promising renewable rawstuff for the southern regions of EU. The plant can be utilised as a source for the production of a natural sweetener (Food), as a source of Chlorophyll (Non-Food: Oral hygiene products, medicine), as a source for Phytosterols (Non-Food: Medicine: raw stuff for the synthesis of oral contraceptives, cholesterol suppressing medicine, antitumor activity against prostata tumors and activity against rheumatism), the sweetener can be converted in gibberellins by fermentation (Non-Food: Agrochemical), the vegetative residue can be used as fodder especially for sheeps and goats (Feed) and the stalks can be used as a source of cellulose (Non-Food: Celluloselndustry). The added value for this new crop and its green chemicals is about 50.000 ECU/ha. The cultivation of Stevia will increase the farmer income and will create employment in rural areas. By its climatic and agronomic characteristics Stevia can be cultivated in tobacco areas and can substitute partly tobacco, a crop in crisis. For the new reformed tobacco sector, Stevia can be a real alternative for the people working in this area. For Non-Food purposes the crop can be cultivated on land of the set aside scheme.  It therefore makes sense, in the economic context of the CAP, to fix as an objective the introduction of Stevia in Europe, a crop with a high added value, and which is perfectly suited to poor land in southern Europe. As an example for the potential of Stevia rebaudiana figures from artificial sweeteners are demonstrated: Worldwide about 62.000 tons of artificial sweeteners are consumed yearly. This demand can be substituted by the cultivation of about 186.000 hectars of Stevia. In the EU the yearly demand of artifical sweeteners is about 10.000 tons which can be
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Superheated Steam-based process for low energy and high quality drying of food and food residues'.

assistant: **Objectives**

The EU market for processed foods is changing: there is now an increasing demand by consumers for foods that have undergone fewer changes during processing, foods that resemble more to the original raw materials with high nutritive values, flavour and a “natural” image.These pressures are especially significant for a SME dominated sector, the dried foods: although it represents more than €8 billion in Europe, the sales of dried foods are currently in stagnation or declining. Indeed, not only the food processing machinery SMEs must improve the drying process to achieve high quality dried food to meet the customer high requirements, but also they must tackle the energy consumption and pollution issues which are typical of such equipment.For the food machinery SMEs, today is the time to respond to these changes and enable the dried food industries to recover their competitiveness. To do so, they need to face 3 main challenges: Low quality of the final dried products, High energy consumption to dry the raw materials, Significant environmental pollution, via CO2/odor emissions.The STEAMDRY project gathers 4 SMEs and 1 association, which aims at developing a new drying plant to allow food producers and food processing SMEs to dry their foods with efficiency, high quality and sustainability, thanks to:-Innovative drying technology, using superheated steam at low pressure, ensuring efficiency through better heat transfer and a better quality of product due to lower temperature-2-step cleaning system to remove the dust/particles from the extra steam and allow its reuse in the upstream process, reducing the energy bill-New optical multi-sensor integrated in the process control, to monitor the food drying quality along with the energy balance of the system.The STEAMDRY process wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Synthesis and characterization of electromechanically active composites of mesogenic elastomers and electrically active nanoparticles' (ELACEM) targeting Sixth Framework.

assistant: **Abstract**

This project focuses on the preparation and chemical/physical characterization of a new kind of composite materials, specifically the composites of liquid crystalline elastomers (LCEs) and electrically active nanoparticles.These materials should retain their original mesomorphic behaviour of pure monodomain liquid crystalline elastomers and in addition exhibit electrical response due to the presence of nanoparticles embedded in the polymer network.We shall seek for the following properties:- The composite should elongate/compress under the effect of external electric field; LCEs known so far can only change their shape thermally. Concurrently the included ferroelectric and dielectric nanoparticles of various shapes and anisotropic properties should reorient. It is the coupling between the orientational order of the particles and the orientation order of polymer segments that should lead to electromechanical response. The orientational redistribution of nanoparticles should determine the elongation of the elastomer and consequently the change in the composites shape.- The composite should change its electrical properties (dielectric constant, permittivity, and/or spontaneous polarization) when exposed to external mechanical strain. A simple elongation should result in the reorientation of nanoparticles and thus induce anisotropic electrical properties. These new composites are expected to carry strong potential for technological and biomedical applications. New synthetic routes preferring high viscosity conditions will be explored.A significant part of the activities within the project will be dedicated to characterization of newly synthesized materials by spectroscopic techniques, in particular with Nuclear Magnetic Resonance.Both the organic and inorganic constituents
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Non-Classical Main Group Chemistry; Supramolecular Chemistry and Catalysis'.

assistant: **Concept**

The classical view of the periodic table suggests, in particular, that there are distinct boundaries between the chemistries of s-block, p-block and d-block elements stemming from the availability and type of valence orbitals present and fundamental properties such as electronegativity. Yet this long-excepted, text-book view can provide a barrier to progress in a number of key chemical areas because it prevents us thinking about the true picture, that there is more commonly a continuum of structural and reactivity properties which overlap large segments of the periodic table. This proposal seeks to move through these barriers by establishing fundamental and practical applications of p-block element chemistry in supramolecular chemistry (the classical domain of carbon chemistry) and catalysis (the classical domain of transition metals).The broad theme of the proposed project is to study non-classical aspects of main group chemistry. This takes the form of two major components which span the non-metallic and metallic areas of the p-block, (i) the development of systematic approaches for the building of macromolecular inorganic systems and their application in host-guest, gas storage and separation, and (ii) the applications of p-block metals in a broad spectrum of stoichiometric and catalytic bond-forming reactions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Membrane trafficking as a link between cell polarity and intestinal absorptive function: from C. elegans to mammalian miniguts' (GUTPOLAR), addressing dissemination and exploitation.

assistant: **Impact**

The GUTPOLAR project aims at sustainably reintegrating an Experience Researcher (ER) who will acquire the necessary knowledge and skills to reinforce European research on rare malabsorption diseases.Food absorption relies on the strong polarity of intestinal epithelial cells and the array of microvilli forming a brush border (BB) at their luminal (apical) pole. Some rare genetic malabsorption disorders, characterized by mispolarized PAR polarity modules and BB structural proteins, are caused by mutations in genes coding for membrane traffic factors (i.e. Myo5B in microvillus inclusion disease/MVID). Despite this functional link, little is known about the genetic, physical and functional interactions between membrane traffic, polarity and BB components in vivo and how they control intestinal absorption.The ER uncovered a new role of the V0 sector of the V-ATPase, a complex that controls membrane traffic through organelle acidification, in both polarity and BB components apical polarity maintenance in C. elegans intestine. Most interestingly, V0-ATPase depletion in C. elegans recapitulates the cellular phenotypes observed in patients with MVID, making this complex a very exciting candidate which mechanism, genetic partners and mammalian function need to be characterized. To this end, the ER will first use genetics and super-resolution imaging to study the trafficking routes and the molecular mechanisms controlled by the V0-ATPase in vivo in C. elegans intestine. Then, he will implement mouse intestinal organoids (thanks to a secondment in H. Farin’s lab, Frankfurt, Germany) and use this model to study the conservation of these mechanisms in mammals.Overall, the GUTPOLAR action will allow to describe evolutionary conserved pathways of polarity maintenance and identify some
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'High voltage, room temperature single-ion polymer electrolyte for safer all solid state lithium metal batteries'.

assistant: **Concept**

The greatest challenges towards the worldwide success of battery-powered electric vehicles revolve around the safety, energy density, and cost of the battery technologies. Solid-state polymer electrolytes and lithium metal anode address these challenges by replacing the flammable and unstable liquid electrolytes and enabling dendrite-free cycling of high-energy lithium metal cells manufactured by sustainable and cost-effective processing. The PSIONIC project advances the development of all-solid-state battery technology by employing amorphous cross-linked Polyethylene oxide (PEO) laminated on the thin lithium foil at the anode and high voltage cathode coated with a single-ion conductive polymer. This will allow to replace the flammable and unstable liquid electrolytes and enabling dendrite-free cycling of high-energy lithium metal cells manufactured by sustainable processing. Special attention will be devoted to the optimization of interfaces between the active material and polymer electrolyte. Materials selection will enable the use of the manufacturing technology available at BlueSolutions, which is readily scalable, based on sustainable processing using solvent-free extrusion. PSIONIC is aiming to develop cells with a safety hazard level 2, since no liquid component will be in the cell at the end of the project. The research and innovation actions carried under the PSIONIC project will not only just contribute to the technological advancements of all-solid-state Li-ion batteries in terms of safety, reliability, performance, cost, and sustainability, but will also enable higher uptake by the electromobility sector and end consumers, paving a pathway towards climate neutrality, and green energy transition.


**Keywords:** Single-ion conductive polymer; All-solid-state