RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Impetus' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

IMPETUS will support and give recognition to citizen science (CS) in Europe. It aims to:* enable more diverse citizen science initiatives (CSIs) to access funding;* bring CS closer to society and policy makers;* acknowledge CS? role in tackling the greatest challenges of our times; and* enable CSIs to contribute to Green Deal (GD) and UN SDG commitments.We will achieve this by:* funding CSIs through 3 open calls, selected on expected impacts, volunteer engagement, EDI, openness and quality data. We will offer 20k? to kick-start 100 CSIs and 10k? to sustain 25 CSIs addressing pressing needs of the European society. Each call will have 2 challenges; we will convene a citizen panel to define one and provide feedback on our work.* setting up an accelerator to provide the funded CSIs with an integrated programme of support, training, mentoring, and resources. The accelerator will facilitate peer learning, enable CSIs to contribute to SDG and GD targets and forge connections with quadruple helix stakeholders.* launching the EU Prize for Citizen Science, awarded to CSIs for outstanding achievements, allowing them to continue and expand their work and showcase it to a wider audience. We will award 3 prize categories for 3 years: outstanding achievements, diversity and innovative grassroots projects. Each time, we will reach out to advisors to identify exceptional nominations and to the citizen panel to vote in the grassroots category.* shaping EU policy in and with CS, through horizon scanning, anticipatory policy and action research, informing policy briefs, webinars and workshops with key policy stakeholders. The aim is to foster more CS data to inform evidence-based policies and identify future directions in CS policy.* developing impact assessment tools and assessing the im
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The role of novel opsins in non-visual light detection in the zebrafish brain' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Light impacts on life by modulating the physiology and behaviour of most living organisms. Both vertebrates andinvertebrates have developed an extensive and diverse range of photoreceptor structures and photopigments, whichmediate these light responses. Clearly light is used for vision, being detected by specialized rod and cone cells in the retinaand processed by the visual centers of the brain. However, light also regulates many non-visual processes, and novel nonvisual photopigments are regularly being discovered. Recent studies have shown a role for non-visual photoreception inseasonal responses, activation of DNA repair mechanisms, entrainment of the circadian clock and sleep-wake regulation,but the mechanisms are far less understood. This phenomenon is particularly extensive in teleosts such as zebrafish, whereall tissues and cells of the adult and larval body are directly light responsive. The purpose of ZNEOPSIN_II is to determine the role that non-visual light detection plays in early development in zebrafish, focusing on neurobiology, the entrainment of the circadian clock and specific aspects of behaviour. I will take advantage of zebrafish, a genetic model organism available at the host lab, a leading zebrafish circadian biology lab at University College London, which is also one of the larger zebrafish research communities in Europe. The latest technical approaches for gene knockdown (CRISPR/Cas genome editing), and luminescent/fluorescent imaging, together with classical molecular biology techniques, will be combined with state of the art behavioural assays developed in zebrafish. The results of ZNEOPSIN_II will provide invaluable insights into the biological significance of non-visual light detection, and the roles played by a range of newly discovered op
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'ICT for Energy Efficient Airports' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

CASCADE will develop facility-specific measurement-based energy action plan for airport energy managers underpinned by systematic Fault Detection Diagnosis (FDD) Methods. CASCADE will develop a framework and methodology to underpin the execution of customised ICT solutions building upon existing ICT infrastructure. A measurement framework and minimal data set will be established that control and benchmark equipment performance, optimise user behaviour, and match client specifications. FDD enables beyond the state of the artenergy management because FDD can be used to detect problems in system design, equipment efficiency, and operational settings. CASCADE will enable transformation of FDD into actionable information by developing an energy action plan that links Actions-Actors-ISO Standards through a web-based management portal. CASCADEwill provide the European Commission with the opportunity to engage the European airport community on the topic of energy efficiency. Airports are politically visible and public hubs that connect Europe. ACI-Europe has committed its support to the proposal providing a direct exploitation channel to 400 of the 500 EU-27 airports. Furthermore, CASCADE embodies what E2B and the PPP is trying to do. It is industry shaped, politically visible, provides near term impact, creates jobs, and meaningfully addresses 20-20-20 targets. Airport managers are under considerable pressure to economise in energy management and need tools to provide adequate support. From CASCADE, they demand solutions that can integrate with existing ICT solutions installed at their facilities. From them, CASCADE can obtain access to their terminals, HVAC systems, renewable energy systems, co-generation plants, parking areas, maintenance hangers, security systems, etc. HVAC
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Innovation Relay Centre Paris Ile-de-France' (2002-2006).

assistant: **Concept**

We want to propose to our clients tailor-made services, so we shall adapt our actions to our market segmentation (see WP1). We shall propose high quality added-value services in order to get long term users of IRC services. We shall capitalise the positi ve results of our pilot action Being successful with TTT in Europe" (see WP1) in which 8 companies are implementing a TTT agreement with the technical support of a private consultant and an IRC consultant, the financial support of Anvar, and the collabo ration of the IRC network. We intend to intensify the strategic and operational collaboration with regional innovation actors such as the technological diffusion network-RDT-, the National Contact Points network, the French Eurêka team, the EIC, the BI C, ESA to get a strategic position in the FP6 for companies willing to transfer, integrate and promote their RTD results and technologies. We plan to organise selected brokerage events corresponding to our SMEs needs. We want to improve the organisation process in order to get high quality technology offers and requests, pre-validated one-to-one meetings and a better participation of companies during the event. So we could improve the rate TTT agreements/number of meetings. We want to continue impleme nting SMEs missions (see WP2) which are one of our best way to get TTT agreements. These missions will take place in Paris or abroad with the close and strong collaboration of 1 to 5 other IRCs, and with a panel of 10 to 15 regional companies and laborat ories. We keep in mind the very necessary and fruitful collaboration with the IRC network and the Central Unit (see WP3) with which we shall transfer and exchange our know-how and tools through the thematic groups, the brokerage events, the company miss ions, and bilateral pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Probing and controlling ultrafast electron and ion dynamics in operating battery electrodes and interfaces' (FemtoCharge) under Horizon Europe.

assistant: **Objectives**

Charge dynamics lie at the crux of electrochemical energy devices, and in-particular batteries, impacting everything from durability to capacity. On mesoscopic time (ns to s) and length scales (nm to mm) we have a good understanding of charge transport related phenomena in batteries. However, when it comes to faster femtosecond/picosecond processes and those at nanoscopic interfaces, our insight remains limited. This is a critical problem. In this regime lie:(a)the individual electronic/structural steps in the redox chain that can cause electrode capacity loss via charge-transfer to inactive/unstable states(b)(de)solvation processes that inhibit fast charging through chemical imbalances at electrode/electrolyte interfaces(c)sluggish ionic hops limiting the use of many solid-electrolyte and electrode materialsIn FemtoCharge, I will take the conceptual leap needed to elucidate ultrafast interfacial dynamics in batteries, by merging femtosecond spectroscopy/microscopy and operando battery science. My novel approach is based on my pioneering work to optically image ultrafast spatio-temporal dynamics, and their coupling to structure, in nanomaterials, and probing in the complex solid/liquid environment of batteries. I will leverage this approach to: 1.uncover optimal electronic/structural pathways for charge-transport in current and developing electrode materials 2.quantitatively reveal potentials and solvation mechanisms at electrode/liquid electrolyte interfaces3.use lattice vibrations to manipulate ion-hopping in solid electrodes/electrolytesI will deliver blueprints for building new electrode/electrolyte battery materials, strategies for external stimuli-based tuning of battery charge-transport and game-changing operando tools for characterising charge-dynamics, particul
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'INTEGRATING GENOMICS-BASED APPLICATIONS TO EXPLOIT ACTINOMYCETES AS A RESOURCE FOR NEW ANTIBIOTICS', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

ActinoGEN is an integrated project aimed at developing novel genomics-based approaches to exploit hitherto overlooked genetic resources for new antibiotics. Drug discovery will focus on (1) accessing new antibiotic biosynthetic pathways from diverse actinomycetes that have yet to be cultured; (2) activating cryptic pathways from well-characterised actinomycetes; and (3) engineering novel hybrid antibiotics by combinatorial biosynthesis. To greatly accelerate the drug discovery process, a parallel strategy will be to engineer generic hosts optimised to produce high antibiotic yields. With the complete genome sequence of the model actinomycete, Streptomyces coelicolor, and mobilization of a pan-European effort to apply newly developed multidisciplinary post-genomic technologies, a holistic understanding of the physiology and regulation of antibiotic biosynthesis is achievable for the first time. This will, in turn, permit rational intervention to engineer generic hosts for high-yield antibiotic production. This synergy of discovery linked to overproduction will place the European biotechnology sector at the forefront of developing much-needed new antibiotics to combat multi-drug resistant pathogens.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Novel etiology of autoimmune disorders: the role of acquired somatic mutations in lymphoid cells' (M-Imm).

assistant: **Innovation**

Molecular pathogenesis of most immune-mediated disorders, such as of autoimmune diseases, is poorly understood. These common maladies carry a heavy burden both on patients and on society. Current therapy is non-targeted and results in significant short- and long-term adverse effects.Large granular lymphocyte (LGL) leukemia is characterized by expansion of cytotoxic T- or NK-cells and represents an intriguing clinical continuum between a neoplastic and an autoimmune disorder. Patients suffer from autoimmune cytopenias and rheumatoid arthritis (RA), which are thought to be mediated by LGL cells targeting host tissues. My group recently discovered that 40-50% of LGL leukemia patients carry in their lymphoid cells acquired, activating mutations in the STAT3 gene – a key regulator of immune and oncogenic processes (Koskela et al, N Engl J Med, 2012). This breakthrough discovery gives insight to the pathogenesis of autoimmune disorders at large. I present here a hypothesis that a strong antigen-induced proliferation is a mutational driver, which causes somatic mutations in lymphoid cells. When mutations hit key activating pathways, autoreactive cells acquire functional advantage and expand. The target antigen of the expanded clone determines the clinical characteristics of the autoimmune disease induced. To prove this hypothesis, we will separate small lymphocyte clones from patients with autoimmune diseases and use sensitive next-generation sequencing methods to characterize the spectrum of somatic mutations in lymphoid cells.  Further, we will study the function of mutated lymphocytes and examine the mechanisms of autocytotoxicity and end-organ/tissue damage. Finally, we aim to understand factors, which induce somatic mutations in lymphoid cells, such as the role of viral i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Human Gonad Developmental Cell Atlas' (HUGODECA), addressing dissemination and exploitation.

assistant: **Impact**

The single ground-breaking goal of the HUGODECA project is to describe the cellular composition and organization of the developing human gonads and to understand how it changes during sex determination into testes in males and ovaries in females.  What are the underlying mechanisms and first molecular and cellular events that accompany the differentiation and divergence of embryonic gonads? How and when do male and female cell lineages diverge and specific traits emerge? HUGODECA focuses on healthy gonad development, but our reference model will be tested using specific ex vixo assays mimicking Differences/Disorders of Sex Development (DSD).To reach this ambitious goal, the HUGODECA consortium brings together leading European academic and industrial experts (from 5 different EU countries). It includes active contributors and executives of the Human Cell Atlas (HCA) which will ensure complementarity with other ongoing HCA efforts. The overall HUGODECA concept is grounded on the integration of multiple synergistic expertise and technologies: Single cell profiling, Spatial transcriptomics, 2D Mass cytometry and cyclic immunofluorescence and 3D imaging of optically cleared gonads. HUGODECA will implement novel tools, analytical and computational methods to process and integrate multidimensional OMICS and image data across different platforms. It will evaluate the accuracy of ex vivo culture models of human gonadal development and assess consequences of altering key signaling pathways.HUGODECA will build the first multiscale developmental cell atlas and unprecedented reference maps of male and female human gonads. It will implement an interactive and multi-dimensional online portal for clinicians, scientists and public including DSD patient associations. HUGODECA shall impro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Innovative Quantum Dot material technology for stunning colours and energy efficiency in QLED televisions' in the context of a Horizon 2020 call.

assistant: **Objectives**

Quantum Dot (QD) displays represent the next generation of TVs with enhanced, brilliant colours, precise visualisations, and greater energy efficiency. However, the materials, cadmium and indium, currently uses to produce these displays have multiple drawbacks. The use of Cadmium in the European area is restricted due to health safety reasons. Indium-based QDs have been highly lacking in performance. They have lower performing quantum yields (QY), measuring at averages of 80%, while also showing poor color performances due to high narrow emission spectrums (FWHM) at more than 40nm. Both technologies have very high production cost due to an extensive production process. We have developed Perovskite-based Quantum Dots that show the highest Quantum Yield and therefore the highest power saving properties. Our Perovskite QDs also show such a narrow FWHM that enables to span the whole colour spectrum as perceivable by the human eye. These features will allow to produce brilliant colours, precise visualisations, and energy savings for the next generation of TV screens. Our high performance QDs, add up to 50% more colours and save up to 30% of currently expended energy for operations compared to QD-enhanced LCD TVs from industry-leader Samsung. We are currently making sales on our R&D scale QDs, as well as sales on other nanomaterials in solution processed OLED and solution processed solar cells. We have currently 15 full-time employees that help us power our operations and support to deliver our sales requests. We have come to the point where our operations would have to significantly ramp-up. The Phase 2 project will allow to set-up the production of Perovskite QDs on an industrial level in order to become a key supplier of optical film manufacturers in the TV screen producti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Advanced integrative solutions to Corrosion problems beyond micro–scale: towards long-term durability of miniaturized Biomedical, Electronic and Energy systems' (2014-2020).

assistant: **Innovation**

mCBEEs Innovative Training Network is a joint venture between academy and industry with a primary goal to train young researchers in the field of corrosion and corrosion protection of micro- and nanodevices. The network focuses on the study of corrosion mechanisms beyond microscale of components in miniaturized systems in different environments using localized techniques, and the development of multifunctional protective coatings to increase the long-term durability of such components. Corrosion phenomena occurring in micro- and nanodimensional components can develop in a completely different path than in their bulk counterparts and corrosion might influence the functional properties of small components in a much more severe manner. Three main strategic fields where corrosion could seriously compromise the performance of micro- or nanodevices have been identified: biotechnology (micro/nano-robotic implants, micro/nano-electrodes for recording and stimulating neuronal activity, or micro-featured prosthesis implants); electronics (micro/nano-components in electronic boards, magnetooptical thin films, multiferroic micro/nano-devices); and energy technology (metallic foam-based micro- and nanostructured electrodes, self-standing nanoarchitectures). Several disciplines (physics, electrochemistry, engineering, biology and robotics) converge to provide a multidisciplinary approach to accomplish mCBEEs goals. The ITN brings together 15 beneficiaries and 3 partners including 4 research institutes and 4 private companies belonging to 9 EU Member states, and to 2 associated states (Switzerland, Turkey). The Consortium complementarity will enable a high-level, multifaceted educational programme, where specials efforts will be done to bridge fundamental research with industrial appl