RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Arylpyrrole-based Transmembrane Transporters for Induced Chloride Regulation in Cystic Fibrosis Epithelial Cells'.

assistant: **Innovation**

The regulation of cellular ion concentrations is critical for a range of physiological processes. Malfunction of transmembrane Cl-/HCO3- antiport has been associated with cystic fibrosis and other channelopathies. Changes in pH via H+/Cl- symport cause deacidification of acidic organelles leading to cytoplasmic acidification, an early event in apoptosis. Synthetic anion transporters have been studied mainly in artificial vesicles for their ability to facilitate Cl-/HCO3- antiport and H+/Cl- symport. However, just recently it was shown that the most efficient transporters in liposome assays not always correlate to the most efficient conductors in live cell studies, most likely due to the differences between the model membrane used for the vesicle studies and the biological membranes present in cells. Therefore, a need has arisen for a systematic methodology to quantify the ability of synthetic compounds to facilitate transmembrane chloride transport in live cells. A set of prodigiosin-inspired transporter agents will be synthesized applying a newly discovered route towards 2,5-diarylpyrrole moieties. Their transmembrane anion conductor properties and pH dependency will be investigated first in unilamellar vesicle assays, to determine the transport mechanism. Further, the Ussing technique will be applied to quantify the transport efficiency in cystic fibrosis epithelial cells and to set up a systematic method for high throughput screening towards potential lead compounds in the quest against channel replacing therapies. Fluorescence in vitro cytotoxicity assays for a range of cancer cell lines will be performed and the compounds potency to introduce apoptosis will be determined.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Thermal utilization of virgin and residual biomass in Brianza (Italy) for district heating and electric co-generation' to be submitted under Sixth Framework.

assistant: **Abstract**

Thermal utilization of biomass in distributed power plants, both for heat generation and possibly for heat and power co-generation, feeding district heating networks, represents a priority action with respects to the objectives of the European Community energy policy, in terms of reduction of CO emissions, energy supply security, energy efficiency, environmental improvement at local level in highly polluted residential areas and social acceptability. Properly selected projects may represent the least cost investment towards these objectives. The proposed study aims to reduce the barriers relevant to knowledge of the biomass market, development of new technologies and identification of effective investment opportunities and intends to verify the financial sustainability of the best projects and the possible requirement for public support.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Synchronised neuro-Memristive Architecture for Reinforced learning Technology'.

assistant: **Innovation**

Rapid progress in the regime of Artificial Intelligence and Internet-of-Things has enthused the development of fast and energy-efficient hardware to support future computing needs. One of the most prominent solutions is the deployment of cross-disciplinary resources for mimicking the performance of a Human Brain, also known as neuromorphic computing. It relies on electronic components that could replicate the functioning of neurons and synapses. Designing such novel electronics needs the development of cost-effective, fast and reliable materials with tunable functionality. A fundamental understanding of these materials will pave the foundation of innovative device designs and strategies for their large-scale integration for neuromorphic architectures. In this context, the proposed project intends to deliver artificial neurons by developing thin-films of a novel material (TbMnO3) that is capable of demonstrating a Negative Differential Resistance (NDR). The idea is to utilise the fundamental understanding of multi-dimensional (electrical, optical, mechanical and magnetic) control of NDR which is not explored yet and is possible in TbMnO3. NDR enables a two-terminal device to display self-oscillations due to applied electrical spikes. The spiking electrical currents could be used to govern the behaviour of these oscillations and emulating the leaky, integrate, and fire behaviour of biological neurons. Once such a performance is achieved, the device will further be integrated into oscillatory neural networks array for demonstration of complex computing tasks such as image recognition and imitating human behaviour.    The project will unite the applicant’s expertise in synaptic devices and materials engineering with the extensive experience of the host-labs in thin-film and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'A multi-arm, multi-stage trial for cutaneous leishmaniasis - MAMS4CL', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Cutaneous leishmaniasis (CL) is a neglected tropical disease affecting more than  one million people globally each year. In Ethiopia alone more than 40,000 people are thought to be affected annually. Infection results in stigmatising, visible, chronic, scarring skin lesions which cause permanent morbidity and significantly affect mental health, household financial stability and life chances.There is a major need for new therapeutics for CL. The current first line therapy is intramuscular sodium stibogluconate. Treatment is often ineffective, painful, and associated with adverse effects. The complexities of administration mean treatment is restricted to a small number of centralised facilities. As a result the majority of patients receive no treatment. There are a number of promising alternative and novel therapeutics for cutaneous leishmaniasis which may be more effective, more tolerable and more suitable for widespread scale up. However the evidence for these therapies is lacking and this vacuum means that policy cannot be easily changed.Our consortium of leading European and African research institutions proposes a step-change in the evidence base for CL. We will use a  multi-arm, multi-stage randomised trial – MAMS4CL - to simultaneously evaluate multiple novel therapeutic interventions. This approach will reduce the time required to identify optimal treatment strategies for CL and transform the therapeutic landscape. We will identify and test five candidate interventions and assess their safety, efficacy, cost-effectiveness, and acceptability. The interventions have been selected as they offer: more tolerable administration, shorter treatment duration or home-based therapy. We will embed within MAMS4CL detailed pharmacokinetic, health economic and social science stu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The Drums' Many Lives: Stories of a Mapuche Shamanic Being in European Collections' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Stories, like kulxug (drums), can bring newen (vital energy) back. This idea, of shamanic origin, is what guides this project's aims. Collaboratively conceived, this research engages with twenty-five Mapuche drums under European Museums' custody, aiming to retell their stories and, in so doing, reclaim their vital energy back home while reconceiving what repatriation may look like from the Mapuche perspective. In conversation with this perspective, this project will gather and analyze data about the drums, the most relevant mogen (living beings) in Mapuche shamanism. The objectives are (1) to trace the drums' provenance; (2) characterize the drums' musealization process; (3) document the drums' material identities; (4) collaboratively produce storytelling about the drums' lives, emphasizing the Mapuche traditional knowledge; and (5) re-conceptualize repatriation considering the stories' ability to reclaim vital energy.This project was designed collaboratively with Mapuche communities and representatives engaged with repatriation. Its methodology combines social sciences and humanities methods with gvxan (conversation), a Mapuche discursive and analytical genre based on storytelling. First, archives, legislation, museum practices, and the drums' materiality will be studied using material culture, legal, anthropology, history, and archaeology methods. Then, all data will be collectively analyzed with Mapuche communities during territorial meetings in Southern Chile. This will result in the storytelling of the drums' lives and rethinking what repatriation might be in this case. The research brings non-Western peoples' ontological self-determination to the fore, querying how repatriation has been practiced. As a result, while it deals with a priority issue for the Mapuche c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Advanced - Techniques for Evaluation of Sustainability Assessment Tools' (SUSTAINABILITYA-TEST).

assistant: **Concept**

To realize progress towards the ambitions on Sustainable Development (SD) the EU and others should set wise objectives and ensure effective implementation. This requires proper policies and a consistent implementation process. To make equitable and ambitious decisions on which policies to develop and to review the progress made towards the SD goals, tools (i.e.methods, models, approaches and appraisals) are needed that support strategy development, ex ante sustainability impact assessments (Seas) as well as policy reviews. This project will assist in improving both Seas and the SD strategy definition, by high-level validation of the tools using consistent and comprehensive evaluation framework. First, a draft evaluation framework and key aspects of SD will be formulated. Then a catalogue of state of the art tools will be made and a preliminary evaluation of the tools in the context of different policy questions will be carried out based on literature reviews. In this phase the project will focus on water, climate and agriculture & land-use policy questions. Then an array of tools will be tested in one case study on agriculture& land-use. This will lead to a final evaluation framework that indicates how the tools relate, the merits of each tool, the circumstances under which they can be used, the pros and cons and the extent to which they integrate externalities of policies. Moreover, the evaluation framework will show which tools are useful for answering which key aspects of SD and will identify the trade-offs of using the different tools for addressing the three pillars of Dafter this project there will be a better insight for policy-makers and those carrying out Seas, what tools they can best use in decision-making or assessment processes, given the available resource
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'The Role of Binary-Stripped Stars: from Atomic Scales to Cosmic Dawn'.

assistant: **Concept**

A third of all massive stars are predicted to lose their hydrogen-rich envelopes through interaction with a binary companion star, leaving the helium core exposed. These stripped stars are thought to be the main progenitors of hydrogen-poor core collapse supernovae, to constitute two necessary steps in the formation of merging neutron stars, and to provide so copious amounts of hard ionizing radiation that they contributed to cosmic reionization. Despite their importance, it took over half a century until we last year confirmed their predicted existence with observations. This means that theoretical models that previously had few to no observational benchmarks now face reality. 2SStars is designed to challenge theory with observation, while adressing the questions (1) What is the role of stripped stars in binary star evolution? and (2) How can stripped stars be used to understand different parts of astrophysics? We will study the stripped star binaries in detail to obtain measures for example for stellar winds, mass transfer efficiency and X-ray emission. We will also venture beyond binary evolution and use stripped stars as laboratories to investigate both how magnetism and rotation operate in stellar interiors and what the source of the enigmatic He II emission observed in galaxies across redshifts is. To fully exploit the new discovery, 2SStars is constructed as a symbiosis of observations and theory, for which we will use and develop modern codes of binary stellar evolution, hot star atmospheres, nebular spectra, and stellar populations.   With upcoming space missions in both the ultraviolet (UVEX) and milli-Hz gravitational wave regime (LISA), and new survey telescopes (VRO/LSST, WFIRST, 4MOST) and ongoing gravitational wave detections (LIGO/Virgo/KAGRA), a large f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Emerging Nanopatterning Methods' (NAPA).

assistant: **Innovation**

The growing importance of nanotechnology for the European Research Area is reflected in theFP6 Thematic Priorities. It is foreseen that most of the projects submitted to the Priority Area 3 (NMP) will need and develop nanopatterning techniques in one way or another. The Emerging Nanopatterning Methods (NaPa) consortium integrates the new patterning methods into one project, both anticipating and responding to the increasing need for technologies, standards and metrology required to harness the new application-relevant properties of engineered structures with nm-scale features. The NaPa consortium complements the deep UV technology by providing low-cost scalable processes and tools to cover the needs of nanopatterning from CMOS back-end processes through photonics to biotechnology. To achieve this, research in three technology strands is proposed: nanoimprint lithography, soft lithography & self-assembly and MEMS-based nanopatterning. While the former is at a crucial embryonic stage, requiring prompt consolidation to yield its first products in one or two years, the other two will result in applications towards the end of the project. Research in three overarching themes required by all strands: Materials, Tools and Simulation will be undertaken. NaPa brings together 35 leading academic and industrial European institutions with a vast amount of recent know-how on nanofabrication, partly developed within FP5. In total, 3500 person months will be contributed by the partners to the project. Complementing R&D, the consortium will design exciting nanoscience and nanoengineering courses to advance the training of the next generation of scientists and engineers and to create a positive attitude towards science among young people. Dissemination activities towards the lay public
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Decontamination and valorisation of tannery sludges with chromium recovery' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The actual treatment in the WWTP involves the production in the thickener of a suspension with a low solid content that is filtered producing sledges with more than 60% of humidity. This project is intended to study the concentration of thickened sledges, the teaching of chromium contained in the sledges, the filtration stage in order to produce sludge with no more than 15% of humidity and the recovery of chromium from the leaching solutions. The leaching stage will involve a selective acid leaching of chromium, filtration of the leached suspension in a specially designed diaphragm plate filter press, with cake washing and cake drying. This technology has to be studied in detail in order to achieve the production of sledges with no more than 15% of water. The final destination of these dry sledges (landfill, agriculture, construction materials etc.) and the recovered chromium is going to be studied.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'COating for SMArt GREENhouses' to be submitted under Horizon 2020.

assistant: **Abstract**

Plants do not harvest the whole solar spectrum equally at the different wavelengths. They indeed reflect green, absorbs red and blue, so that we see them green. The consequence of that is that the solar spectrum is actually not optimised for energy conversion. However, incoming solar spectrum can be modified in order to shift less efficient wavelengths to more efficient one (like green to red) using fluorescent pigments or phosphors. In this way, photosynthesis efficiency can be increased. Meanwhile, when one uses standard fluorescent pigments implemented in a coating at the top of a greenhouse, half of the converted sunlight is emitted back to space due to their isotropic emission, thus lowering the conversion efficiency. To overcome this limit, we propose to use the properties of nano antennas for which it has been shown that they can change the emitting direction of pigments when they are placed in their vicinity. We will design a greenhouse coating that enhance photosynthesis by increasing the effective light inside greenhouses using coatings having nano-antenna phosphor pairs. Firstly, we will perform numerical calculations considering near field radiation and fluorescence, in order to find an optimum design in terms of antenna and phosphor size. Then, the coating will be produced in collaboration with a deposition facility using corresponding parameters from the numerical study. Finally, the actual design will be characterised using spectroscopy to determine the discrepancy between numerical and experimental study. Further actions like changing numerical solver and/or fabrication methods will be considered after a feedback from the two studies.


**Keywords:** Photosynthesis, fluorescence, near field radiation, greenhouse, coating
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Design Study for a Large Scale Underground Research Facility on Safety and Security' (L-SURF), addressing dissemination and exploitation.

assistant: **Impact**

Research on safety and security in enclosed underground spaces is of outstanding importance as current incidents (tunnel fires, terror attacks in metros etc) have shown. However currently the EU competence related to safety and security is largely unstru ctured, fragmented and mostly national oriented. Especially missing is a large scale research facility. The necessity for a European wide initiative in these respects also was identified and clearly expressed during the 1. International Symposium on safe and reliable tunnels, held in Prague in February 2004. Within the Design Study for L-SURF all relevant aspects for such a facility will be elaborated to a level that the facility could be established at least as a legal entity with the necessary struct ures and activities and that preliminary concepts and plans for the physical construction are laid out. The Study: describes the constructional lay-out of the facility, based - if applicable - on an entirely new concept for easily creating any contours , shapes and sizes of enclosed spaces needed, but also all other aspects like installations, environmental impacts etc. The concept will allow novel approaches to R&D work describes innovative measuring sensors, based on the latest technologies (e.g . nanotechnology) available evaluates the research needs and outlines the R&D - activities develops an integration process for the existing and projected national facilities with their competences and researchers, thus restructuring and improving the relevant EU competence while simultaneously showing ways for using R&D funds more economically shows ways and means to raise the necessary funds for the different stages in the setting up of the facility includes a business plan for a new legal entity dedicated to the establishing o