RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Engineering Bone Marrow Bioreactors for the Infinite Production of Blood Products' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Life-saving blood replacement therapies depend entirely on voluntary donations, but demand surpasses supply. In the EU, 25 million blood donations are collected annually, yet shortages persist with about 20% yearly increase in demand. A promising solution is preservation of hematopoietic stem cells (HSC) in the laboratory to provide a limitless, off-the-shelf source of blood cells. In vivo, these HSC, primarily residing in the bone marrow (BM), continuously regenerate blood. Yet, in vitro attempts to recreate this lead to rapid loss of HSC self-renewal and differentiation capabilities. I hypothesize that this is related to the lack of necessary cues of the BM niche created by its highly vascularized extracellular matrix (ECM) where HSC are maintained during adulthood. In InfiniBlood, I will advance Xolography, a new two-colour volumetric manufacturing technology, into a unique continuous bioprinting process to engineer the first BM-like material bioreactor capable of sustaining HSC self-renewal and differentiation for extended periods (months) in vitro.To achieve this, I will 1)develop BM mini-tissues (organoids) within novel two-colour photoinitiators and viscoelastic hydrogels with functional proteins, thus recapitulating BM ECM properties allowing for guidance of HSC maintenance; 2) engineer perfusion of BM organoids for nutrient and oxygen supply, ensuring long-term HSC maintenance in culture and mature blood cell collection; 3) advance Xolography to continuous bioprinting on a moving belt (roll-to-roll), thus enabling indefinite extension of build volumes, ultimately producing clinically relevant blood cell amounts; and as proof-of-concept, 4) investigate the ability of bioreactor-cultured HSC, to self-renew and differentiate into erythrocytes and thrombocytes. Ove
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Equilibrium methods for Resource Allocations and Dynamic Pricing' (EQUIPRICE) under Horizon 2020.

assistant: **Objectives**

This project seeks to build an innovative economic toolbox (ranging from modelling, computation, inference, and empirical applications) for the study of equilibrium models with gross substitutes, with applications to models of matching with or without transfers, trade flows on networks, multinomial choice models, as well as hedonic and dynamic pricing models. While under-emphasized in general equilibrium theory, equilibrium models with gross substitutes are very relevant to these problems as each of these problems can be recast as such.Thus far, almost any tractable empirical model of these problems typically required making the strong assumption of quasilinear utilities, leading to a predominance of models with transferable utility in applied work. The current project seeks to develop a new paradigm to move beyond the transferable utility framework to the imperfectly transferable utility one, where the agents utilities are no longer quasi-linear. The mathematical structure of gross substitutes will replace the structure of convexity underlying in models with transferable utility.To investigate this class of models, one builds a general framework embedding all the models described above, the equilibrium flow problem. The gross substitute property is properly generalized and properties (existence of an equilibrium, uniqueness, lattice structure) are derived. Computational algorithms that rely on gross substitutability are designed and implemented. The econometrics of the problem is addressed (estimation, inference, model selection). Applications to various fields such as labor economics, family economics, international trade, urban economics, industrial organization, etc. are investigated.The project touches upon other disciplines. It will propose new ideas in applied ma
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Enabling Hydrogen-enriched burner technology for gas turbines through advanced measurement and simulation' (HyBurn) under Horizon 2020.

assistant: **Objectives**

A major impediment to the economic viability of carbon-free renewable energy sources such as wind and solar power is an inability to effectively utilize the power they generate if it is not immediately needed. One option to address this is to use excess generator capacity during off-peak demand periods to produce hydrogen (H2), a high energy-content, carbon-free fuel that can be mixed with natural gas and distributed to end-users via existing natural gas pipeline infrastructure, where its energy content is recovered via combustion in conventional gas-turbine (GT) power plants. H2-enrichment, however, dramatically alters the combustion dynamics of natural-gas and its effect on turbulent flame dynamics, combustion stability and pollutant formation in GT combustors is not well enough understood today for this scenario to be safely implemented with existing power plants.The objective of this study is to facilitate Europe’s transition to a reliable and cost-effective energy system based on carbon-free renewable power generation. It will accomplish this by developing advanced laser measurement techniques for use in high-pressure combustion test facilities and using them to acquire the data necessary to develop robust predictive analysis tools for hydrogen-enriched natural gas combustor technology. This data will analyzed in close collaboration with the simulation and modelling teams and used to rigorously test and validate combustion models and predictive analysis tools currently under development.


**Keywords:** turbulent flame, combustion, laser diagnostics, gas turbine, hydrogen-enriched natural gas, turbulence-flame interaction, thermoacoustics, PIV, PLIF
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'A Breakthrough Biomedical Sensor for the Continuous Real-Time Detection of Ischemia, a Contributor in over 10 million Annual Deaths Globally' (IscAlert), addressing dissemination and exploitation.

assistant: **Impact**

Sensocure is an ambitious Norwegian company, established in 2011, to commercialise IscAlert, the World's first implantable micro sensor for the early detection of ischemia.  Ischemia is a restriction in blood supply to tissues, causing a shortage of oxygen, nutrients and inadequate removal of metabolic waste, eventually leading to cell death.  Ischemia is suffered by 30m people globally every year, 10m of whom unfortunately lose their lives. Ischemia is highly preventable if it can be detected early. Unfortunately existing detection solutions simply cannot provide the early, accurate and real time monitoring required by surgeons and healthcare organisations.  In contrast, IscAlert is a user friendly, fast, robust and cost effective real-time monitoring system. It conforms to current medical practice, improves patient outcomes and substantially reduced healthcare costs e.g. less corrective surgery and need for intensive care.We have made significant progress in the past 18 months. Following the completion of pre-clinical trials of the TRL6sensor in 2018, Sensocure has now completed a TRL7 version of the IscAlert sensor. This design is smaller, cheaper and significantlymore sensitive than the previous version.  We now need to embark upon our next and final steps towards commercialisation; completing clinical trials, gaining Class II CE Marking medical device approval for sale in Europe and scaling up our production processes.Following the EIC Accelerator project, we will seek €3.5million in equity investment from the EC. This will allow us to scaleoperations and undertake FDA approval for sales in US markets. By 2027, we will employ an additional 113 staff, annualsales of 38,000 sensors, and have generated total accrued revenues of €59.92m and profits €16.95m.  Market suc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Novel High Temperature Fluoroplastic Composite Lining Material' to be submitted under Fourth Framework.

assistant: **Abstract**

A large number of varied industrial production processes currently rely on thermally processed fluoroplastic lined containers and pipework to resist corrosion of metallic surfaces. Unfortunately present technology is limited to a maximum operating temperature of 100-120 °C for reasonable lifetime of use. This restriction on operating temperature leads to the chemical industry, in particular, employing high cost non corrosive alloys ( Incalloy, Hastalloy etc. ) or pure titanium in production plant construction. It is the purpose of this proposed project to develop a composite technique for a high temperature stabilised lining material based on the incorporation of high strength materials, ( polyaramid, carbon fibres, glass wool and metals) into a laminated structure of fluoroplastics. These materials will increase the safe maximum operating temperature to in excess of 200 °C and significantly extend the application of fluoroplastic linings throughout the process industries; with major cost and maintenance benefits.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Dynamical Recurrent Visual Perceiver' (DRVis).

assistant: **Innovation**

Real-life applications of computer vision often require high-quality visual sensors. With current technology, such sensors are expensive. Empirical evidence from our ERC-funded research of biological vision suggests that eye motion enhances recognition capabilities beyond what could be expected if the eye was functioning as a static camera. Motivated by these findings, here we aim to perform the major computer vision tasks required for many real-life applications, including segmentation, classification and identification, with low-resolution cameras. The idea is to use a series of low-resolution frames from a moving camera, rather than using a single high-resolution image. This novel algorithm, termed here DRVis, can be implemented in software or hardware. Unlike existing solutions that use multiple frames to reconstruct a high resolution image from low resolution ones, DRVis does not need to learn all the particularities needed for reconstruction; instead, it focuses on extracting the necessary features per the given task. The goals of the PoC project are to scale up and diversify our current software system, implement the system in hardware and demonstrate its performance in field conditions and develop the IPR strategy and explore the commercialization potential of our solution. We expect it will be applicable to a wide spectrum of image processing tasks in settings where sensor quality is low but multiple time samples are available including smart agriculture, drone navigation and visual aid devices.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Pancreatic islet dysfunction and type 2 diabetes – beyond the genome'.

assistant: **Innovation**

The prevalence of type 2 diabetes (T2D) is rapidly increasing worldwide and despite great efforts to prevent and cure the disease, the increase persist. There is an urgent need to develop innovative and effective prevention and treatment strategies for T2D. Recent genome-wide association studies were expected to uncover disease-causing mechanisms in common metabolic disorders. Surprisingly, the identified genetic variants only explain a small proportion of the estimated heritability of T2D. Novel studies, going beyond the genome, are therefore needed to identify key mechanisms causing T2D. These studies should focus on pancreatic islets, the tissue of primary pathogenetic importance for diabetes. Also, mechanisms that allow environmental factors to come into play are likely to be important. Epigenetics fulfill such criteria, and our previous work has pioneered epigenetic discoveries in T2D. PAINTBOX is a multidisciplinary research program through which I will combine advanced sequencing technologies and novel epigenetic methods with mathematical models and clinical medicine to develop new prediction and treatment strategies for T2D. Innovative techniques and access to some of the world´s best patient cohorts permit me to address the role of epigenetics in development of T2D in new ways. The annotation of these discoveries will be done using genome-wide epigenomic and targeted gene-editing tools together with mathematics, whereas the translation of those findings will be achieved using powerful prospective cohorts for T2D and clinical studies.PAINTBOX capitalizes on the largest existing human islet cohort and large prospective cohorts, and expertise that I have built-up over the past twenty years, but also exploits novel epi-genomic and gene-editing technologies that hav
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'European Gravity Service for Improved Emergency Management'.

assistant: **Innovation**

Earth observation (EO) satellites yield a wealth of data for scientific, operational and commercial exploitation. However, the redistribution of environmental mass is not yet part of the EO data products to date. These observations, derived from the Gravity Recovery and Climate Experiment (GRACE) mission and in future by GRACE-FO (Follow-on), deliver fundamental insights into the global water cycle. Changes in continental water storage control the regional water budget and can, in extreme cases, result in floods and droughts that often claim a high toll on infrastructure, economy and human lives. The aim of this proposal is to demonstrate that mass redistribution products open the door for innovative approaches to flood and drought monitoring and forecast.The timeliness and reliability of information is the primary concern for any early-warning system. We aim to increase the temporal resolution from one month, typical for GRACE products, to one day and to provide gravity field information within 5 days (near real-time). Early warning indications derived from these products are expected to improve the timely awareness of potentially evolving hydrological extremes and to help in the scheduling of high-resolution follow-up observations. We will provide adequate data products and indicators for tentative integration into the work of the Center for Satellite Based Crisis Information (ZKI, operated by the German Aerospace Center) and its future use within international initiatives such as the Copernicus Emergency Management Service and the International Charter “Space and Major Disasters”. The performance of our products will be assessed with complementary data and post-processed mass products derived from the combined knowledge of the entire European GRACE community unified
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Tax evasion for market control: Predatory economies in practice' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Tax evasion is an economic justice issue in contemporary Croatia. Corporate tax evasion by massive conglomerates contributes to local financial volatility. Bad financial practices at the top of this chain result in economic precarity at its other end. AnthroTax conceptualizes the various local financial practices of tax evasion with a novel framing of ‘hostage barter’. It employs ethnographic field research methods to study how such practices play out between family winemakers in Istria, Croatia, and a massive agribusiness conglomerate with which they do business.  This interdisciplinary project combines classic anthropological concepts with business studies to show how contemporary predatory market exchanges are constructed and how tax evasion is enacted as an apparent ‘natural’ feature of everyday business. The researcher seeks to understand how the emerging economic system works, how hostage barter has become an inevitability of everyday business, how gender influences its practice, and what hostage barter can teach us about predatory economies in wider post-socialist Europe. AnthroTax will advance theory in critical tax studies by introducing a wholly new concept into the field and bring valuable insight to tax evasion processes that will contribute to both academia and government.  Placing an anthropologist at one of Europe’s best business schools, particularly for interdisciplinary, qualitative research, AnthroTax represents an unparalleled training-through-research opportunity for the scholar to advance her creative and innovative research potential. AnthroTax’s interdisciplinarity, methodological strengths, and integration into targeted CBS research groups will facilitate diversification of her competences via skills acquisition, advanced training, and mobility
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Tailoring nanomagnetism via symmetry-breaking at surfaces'.

assistant: **Objectives**

Nanofabrication is becoming a technological reality for the electronics industry as the road map of the magnetic data storage industry predicts nanometer length magnetic structures within the next 5 years. Breakthroughs in local tailoring of nanomagnetism have been reported via reduced dimensional structures. In this proposal, we aim an innovative extension of this approach by tailoring properties via reduced dimensionality and symmetry breaking at surfaces in order to yield novel magnetic behaviour at the nanoscale.The project will involve:- Utilisation of the Liverpool Surface Science Research Centre's internationally recognised multidisciplinary research to create novel and innovative low symmetry 2-dimensional magnetic nanostructures namely: Chiral structures with loss of mirror symmetry (Raval, Barlow); Nanoclusters with loss of reflectional and translational symmetry (Raval, Barrett) and Quasicrystals with loss of translational symmetry (McGrath).- Technically modify host institution's current STM facility to conduct Spin Polarised Scanning Probe Microscopy to enable the novel magnetic structures to be studied at the nanoscale. This will be the key task of the externally recruited experimental fellow who will work closely with Liverpool researchers in the implementation and transfer of this knowledge.- Carry out high-level theory to model the magnetic behaviour and characteristics of the novel, low symmetry nanostructures.The Liverpool group has international experts working on periodic DFT structure calculations (Hofer), STM image analysis (Hofer) and surface dynamics (Holloway and Darling). However, it is critical to advance from these methods to the full potential codes required for a reliable description of the magnetic behaviour. This will be the key task of