RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Fever. Global Histories of (a) Disease, 1750–1840' in the context of a Horizon Europe call.

assistant: **Objectives**

Fever is one of the most basic and pervasive of human experiences. Even before the current COVID-19 pandemic took this to new extremes, fever and the attendant sensations  of burning up, or having ones temperature taken  had long been familiar to men, women and, indeed, children. While fever is a universal feature of humans material existence, however, its relevance and meaning differed from one historical context to another. The proposed ERC project studies fever globally, particularly in societies within or tied to the Atlantic world, in the century spanning from the 1750s to the 1840s  a time when fever was not only considered the most common ailment that afflicted mankind, but also its most fatal one; more persons died of fever than of all other ailments combined, as contemporaries saw it. Given that fever was a threatening, ubiquitous presence for men and women around 1800, we know surprisingly little about it; as one medical historian recently put it, fever has been the invisible elephant in the china shop of the medical past. Premised upon archival research in countries across the world, the various subprojects expose and explain the unusual prevalence of fever in the periods medical record; its persistent association with particular, insalubrious environments rather than contagion; the unceasing relevance of vernacular, folk and indigenous fever remedies in many Atlantic societies; and fevers resonance and relation with similar disease concepts in other, non-European empires. The project also breaks new ground methodologically in its global, new materialist and interdisciplinary approach  its dialogue with the medical sciences, history and philosophy of science, and environmental studies. It poses questions fundamental to our understanding of both the past and t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Rethinking China’s Model of Urban Governance' under Horizon 2020.

assistant: **Concept**

China’s phenomenal urbanisation is of world-historical significance and imposes profound theoretical and policy challenges. This ground-breaking project will rethink China’s model of urban governance through grounded and multi-scalar investigations ranging from neighbourhoods and cities to regions. For neighbourhoods, it unravels the interface between state and society in everyday living space, migrant social agencies and the self-governance of homeowners’ associations under urbanisation and housing marketization. For cities, it interrogates the development strategies and governance of migrant and ecological urbanism as well as the implementation of projects through financial instruments and the land market. For regions, it uncovers entangled state–market relations which redistribute population and economic activities across cities and produce the city-region. The research will be conducted through six cases: Shanghai, Wuhan, Dali, Xiongan, Jing-Jin-Ji (Beijing-Tianjin-Hebei), and the Guangdong–Hong Kong–Macau Greater Bay Area, based upon grounded ethnographic observations, in-depth interviews and close engagement with Chinese researchers and policy makers across different types of neighbourhoods and cities of varying sizes in coastal, central and western regions, and recent national strategic projects. The project is timely for China to implement a UN-endorsed new urban agenda and rethink its model in the face of trade tensions. It will change how we think of China and its governance and be the first of its kind to explicitly consider indigenous perspectives on Chinese urban transformation. This innovative and contextually sensitive research will contribute to entrepreneurial urban governance theories and will offer a theoretically nuanced and grounded explanation of s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'DEaling with conflicts related to MIgration: NEgotiating social cohesion through communication' (DEMINE) targeting Horizon Europe.

assistant: **Abstract**

The DEMINE (Dealing with conflicts related to Migration: Negotiating social cohesion through communication) European Joint Doctorate (DN-JD) network addresses a critical challenge facing Europe: the increasing prevalence of radicalisation and extremism, which threaten social cohesion, particularly in the context of migration. DEMINE's primary aim is to develop an interdisciplinary research and training programme that examines the complex relationships between mediated (conventional and social media) and interpersonal comThe DEMINE (Dealing with conflicts related to Migration: Negotiating social cohesion through communication) European Joint Doctorate (DN-JD) network is a collaborative initiative that spans multiple fields of study. Its main objective is to strengthen Europe's ability to confront a significant challenge: the increasing prevalence of various forms of radicalisation and extremism, which pose a threat to social unity. DEMINE accomplishes this by combining cross-sectoral mobility and a well-rounded mix of research-oriented and transferable skills development. The network aims to establish a much-needed framework for understanding the role and interaction of interpersonal and mediated communication in relations between different groups and conflicts related to migration and globalisation, ultimately contributing to social cohesion. DEMINE has designed a comprehensive research and training programme that delves into the intricate connections between various forms of communication, such as traditional media, social media, and face-to-face interactions. This programme seeks to unravel how different communication channels influence individuals' attitudes and beliefs regarding migration, as well as their impact on intergroup dynamics (social cohesion). This cross-
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'European security and defence policy and the emergence of a shared normative self-understanding' in the context of a Sixth Framework call.

assistant: **Objectives**

The European Union is moving towards a closer political union and envisions future projects of epochal dimensions. Among these projects are the Common Security and Foreign Policy and the European Security and Defence Policy (CSFP/ESDP). But these policy fields are very likely to interfere with national sovereignty and traditions. That is why some people hold that without shared values European governance is condemned to be ineffective, chaotic and irresponsible: Europe doesn't speak with one voice". The issue of European identity formation is therefore of high relevance for political action. The first part of the proposed project will contribute to an innovative theoretical model of collective identity formation.It develops three ideas:1. Collective identities become objects of reflection in situations of crisis, intense social change or when people try to cope with traumatic collective experiences, which challenge their shared normative self-understanding.2. It will be distinguished between numerical identification (categorisation) and qualitative (self-) identification, which may involve collectively shared ethical convictions.3. Questioning positions that claim different languages and cultures were obstacles to political integration that could not be overcome it will be argued that community building proceeds by co-operative problem-solving. In the second part a comparative case study on discourses about the CSFP/ESDP will be realised on the basis of extended literature surveys and on a series of expert interviews in twelve countries including old and new member states and non-EU member states as control group.The study is focussed on characterising the problem-solving situations, the social carrier groups, the normative arguments, and the reorganisation of collectiv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Method for integrated evaluation of benefits, costs and effects of programmes for promoting energy conservation' in the context of a Fourth Framework call.

assistant: **Objectives**

Objectives 1. To review existing studies on energy conservation potentials and barriers; 2. To review in-depth the major national and EU programmes and other policy instruments for energy conservation promotion; 3. To conduct case studies in 6 countries for 2 sectors, and review conservation policies and test the design of the methodology; 4. To formulate recommendations for the EU conservation policies as well as for national governments on policies and programmes to promote energy conservation. Technical Approach An international review of energy conservation studies and policy instruments on their application and effectiveness will be conducted. The modification and evaluation of a dynamic market penetration concept for energy conservation options will be executed. The model takes into account economic, social and behavioral aspects of penetration of energy conservation technology in different market niches and the effects of policy measures upon the penetration. Competition and interaction of options is endogenously included in the model. The resulting (saving of) energy end-use is calculated as well as the CO2 emissions (reduction). The model will be tested to select most effective energy conservation instruments in different energy market environments (different countries, regulations etc.). The link between behavioral market responses and changing incentives/market conditions due to policy measures will be based on a survey technique recently developed and applied in the Netherlands. Expected Achievements and Exploitation The project team will provide: - A review of national conservation studies and programmes on potentials, realisations, incentives, barriers and benefits and costs. Particular attention will be paid to the role of liberalisation of energy markets
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Experimental Evolution of Aging: the genetic link between lifespan, nutrient sensing and fat metabolism' to be submitted under Horizon 2020.

assistant: **Abstract**

Reproduction and diet are the two main factors that affect aging in a wide range of animal species, including humans. Recent studies suggest that the link between these factors and aging is controlled by genes related to fat metabolism and nutrient sensing, but the exact role of these genes in lifespan and late-life health remains to be elucidated. In addition, most of the known 'aging' genes were identified with laboratory-generated mutants or transgenic manipulations. The genetic mechanisms that control natural variation in lifespan, which may depend on subtle changes to known 'aging' genes or completely different genes, are still unknown, whereas these natural alleles are responsible for aging phenotypes observed in natural populations, including in humans.In this project, I propose to study a unique set of experimentally evolved (EE) Drosophila melanogaster lines that have developed an extended lifespan in response to (1) selection on postponed reproduction and/or (2) resistance to developmental undernutrition. We have sequenced the genomes of these lines and identified natural alleles that may underlie variation in lifespan and now plan to (1) compare our genome data to datasets of other long-lived Drosophila lines to identify the most promising candidate genes/alleles for functional testing. (2) I will characterize fat metabolism in the EE lines to investigate the correlation between fat metabolism and aging. (3) I will use the powerful and innovative combination of transgenic RNAi and a 'synthetic recombinant inbred population' approach to test if and how my candidate genes/alleles have an effect on lifespan and fat metabolism.I expect that my results, which may reveal natural alleles that affect aging and how metabolism is involved in this process, will provide
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Mountain Sustainability: Transforming Research into Practice, regional development, new communication tools' (2007-2013).

assistant: **Concept**

The goal of mountain.TRIP is to provide stakeholders, end-users and practitioners with readily accessible and understandable forms of research-based information relevant to sustainable development in mountain regions.Mountain.TRIP will start where other EU projects have finished, translating research findings into useful information and developing relationships between users and researchers. EU research projects generally focus on elucidating truths, not on communicating these truths to practitioners or the interested public. Research projects often produce valuable results, methods, tools and instruments, but at the end of the project neither time nor money remains to disseminate these results among practitioners and to the interested public. Furthermore, research results usually exist in forms recognized by the research community but not easily or quickly assimilated by communities of practice.Mountain.TRIP will close the gap that currently exists between EU project findings and the needs of policy- and decision-makers, stakeholders in economy and environment, planners and administrators, non governmental organisations, end-users, and other members of groups representing the interests of citizens and industry of the most important mountain regions of Europe, hereafter referred to in this proposal as ""practitioners"".Mountain.TRIP will not just disseminate research results but will rather synthesize results from multiple EU projects while adapting the format of that synthesis through continuous interaction with practitioners to meet their needs. The project uses multiple innovative mechanisms to ensure effective interaction with practitioners.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Role of VAP-1/SSAO in arterial wall physiology' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Because changes in the organization and composition of extra-cellular matrix can have consequences on mechanical properties of the arterial wall, understand mechanisms of maturation of the elastin and collagen, (maines extra-cellular proteins) is important.Vascular smooth muscle cells highly express vascular adhesion protein 1 (VAP-1), which display a semicarbazide-amine oxidase (SSAO) activity. Studies using pharmacological inhibitors of SSAO have been previously suggested that SSAO could be important for the arterial wall organization, without excluding that a part of the affects was due to lysyl oxidase inhibition. Lysyl oxydase is the main enzyme establishing cross-links in or between elastin and collagan until now.So I will study tha SSAO role in arterial wall, comparing arteries from wild type, VAP-1 knockout mice (establishment by the host) and VAP-1 knouckhout mice over-expressing VAP-1 in smooth muscles (will established during this project).Histomorphometry and immunohistochemistry will be used to evaluate the arterial morphology and organization, content in elastin and collagen will also be measured. Arterial mechanical properties will be evaluated in vivo with eckotracking and mechanical resistance will be tested in vitro with the collaboration of Lacolley's laboratory. Moreover, because endogenous substrate of VAP-1/SSAO are not known, I will search whether SSAO from vascular smooth muscle cells is able to oxidize directly amine moiety in elastin and collagen to cross-link these molecules.Then, I will verify whether SSAO activity can regulate vascular smooth muscle cells phenotype and expression of extra-cellular matrix proteins. VAP-1/SSAO expression will be measured in function of quality and quantity of extra-cellular matric
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Wonderlogix STUDIO: Towards Seamless Industrial Control' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Automatic Industrial Control Systems rely on obsolete PLC code, causing downtime and revenue losses. At the root lies the gap between design and programming that are performed by specialists with divergent knowledge. WONDERLOGIX STUDIO completely disrupts the balance of power between engineering companies and control system integrators, impacting the design and implementation of control systems. We bring the most cost-effective, robust and developer-friendly tool going beyond traditional IDEs to program PLCs with top-quality code. We shift PLC programming from using primitive language to an extremely high-level language, making it possible to program PLCs without writing a single line of code. Instead, sentences in human language are used to define the logic of operation and are automatically converted to top-quality PLC code. A universal, hardware-independent solution, WONDERLOGIX STUDIO will impact globally the industrial production cycles and performances, fostering revenue increase for European and global markets. Huge benefits of WONDERLOGIX STUDIO are: reduced commissioning time, optimal production, elimination of systems’ downtimes due to SW, minimization of damages and risk to facilities. Highly experienced both technically and commercially, we have a main objective: to bring our solution (in which we have already invested 400k€) to full maturity by integrating functionalities we identified during pilot testing in industrial environments and during demonstrations for prospective clients. Commercially, we tackle a huge market of PLC manufacturers (mostly EU, USA and Asia) and production industries. The Phase I feasibility assessment will include studies to assess technical barriers, evaluate risks, resources and strategies for technological developments and elabo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Characterisation of GABAergic interneurons in the amygdala of GAD65-GFP transgenic mice' (2002-2006).

assistant: **Concept**

Understanding the neuronal mechanisms mediating emotional information processing in the amygdala will require identification of its main cell types and knowledge of their participation in the intrinsic circuitry of this region. Amygdala pyramidal neurons a re spiny projection neurons that use glutamate as an excitatory neurotransmitter.In contrast, most non-pyramidal neurons in the amygdala are aspiny interneurons that use GABA as an inhibitory neurotransmitter. Very few studies linking physiological and morphological properties of the various cell types of the amygdala have been done. The precise identification of the main cell types in the amygdala and knowledge of their participation in the intrinsic circuitry of this region is an essential pre-requisite to understand the neuronal mechanisms mediating the diverse roles of the amygdala subsystems.The aim of this project is to characterise some electrophysiological and pharmacological properties of neurochemically and morphologically identified interneurones in the amygdala. This will be a multidisciplinary study in which intracellular recordings followed by intracellular filling will be combined with immunocytochemical characterisation and cellular reconstruction.For this purpose, a transgenic mouse line expressing a green fluorecescent protein (GFP) under the control of the GAD65 (GAD: glutamate decarboxilase enzyme involved in the synthesis of GABA) promoter will be used. After the single, double or triple intracellular recordings, sections will be fixed and re-sectioned. Immunoreactivity for neurotransmitter receptors, calcium binding proteins and neuropeptides will be visualized by immunocytochemistry and the sections will be processed.The axonal and dendritic patterns of each neurone will be then analysed at high