RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Go with the continuous flow: Asymmetric Synthesis of Bioactive Alkaloids by Multistep Continuous-Flow Processes'.

assistant: **Concept**

In the Realm of Chemistry, asymmetric synthesis has a prime importance as it allows creation of optically pure chemical entities. The synthesis of preferred enantiomer is highly desirable when seeking for specific biological activities owing to the importance of chirality. AsymmFlow delineates synthesis, characterization and application of novel asymmetric supported organocatalysts for enantioselective Pictet-Splengler cyclization in continuous flow/batch to produce tetrahydro-β-carboline (THβC) derivatives. The proposed immobilization strategy gives access to synthesize reusable, robust and stable catalytic systems for asymmetric continuous-flow processes. We aim to develop a sustainable and selective protocol which would give easy access to bioactive substituted-THβC moieties and thus fulfils the demand aiming at lowering their prices in global markets. In particular, the synthesis of the drug Tadalafil usually suffers for poor enantioselectivity, prolonged reaction times, and scale-up issues. It is expected that the development of an alternative protocol for the synthesis of Taladafil will solve those common synthetic challenges and thus, will be highly useful to bring down the market price of this drug all over the world.


**Keywords:** Continuous Flow, Asymmetric Organic Synthesis, supported organocatalysts,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Advanced Reasoning in Arithmetic Theories'.

assistant: **Concept**

Arithmetic theories are logical theories for reasoning about number  systems, such as the integers and reals.  Such theories find a  plethora of applications across computer science, including in  algorithmic verification, artificial intelligence, and compiler  optimisation. The appeal of arithmetic theories is their generality:  once a problem has been formalised in a decidable such theory, a  dedicated solver can in principle be used in a push-button fashion  to obtain a solution. Arithmetic theories are also of great  importance for showing decidability and complexity results in a  variety of domains.  Decision procedures for quantifier-free and linear fragments of  arithmetic theories have been among the most intensively studied and  impactful topics in theoretical computer science.  However, emerging  applications require more expressive theories, including support for  quantifiers, counting, and non-linear functions. Unfortunately, the  lack of understanding of the computational properties of such  extensions means that existing decision procedures are not  applicable or do not scale.  The overall goal of this proposal is to advance the state-of-the-art  in decision procedures for expressive arithmetic theories. To this  end, starting with a recent breakthrough made by the PI, we will  develop novel and optimal quantifier-elimination procedures for  linear arithmetic theories, which we plan to eventually integrate  into mainstream SMT solvers. Furthermore, we aim to improve  complexity bounds and push the decidability frontier of extensions  of arithmetic theories with counting and non-linear operations. The  proposed research requires to tackle long-standing open  problems---some of them being decades old. In short, the project  will lay algorithmic foundations o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Iridium Catalyzed Reductive Cyclization Cascades' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The aim of this fellowship is to develop new reductive cyclization cascades of lactams and amides that establish these feedstock chemicals as important chemical precursors to reactive iminium ions which can be intercepted by pendant nucleophiles and exploited in carbon-carbon bond formation. A range of indole nucleophiles linked to amide and lactam functionality will be investigated for performance in the iridium catalyzed reductive cyclization cascades, and, based on successful proof of concept studies already performed in the Dixon group, a range of semi-saturated nitrogen-containing polycyclic structures possessing one or more stereocentres distributed over an architecturally complex framework should result. As well as studying diastereocontrol in the cascades, catalytic enantioselective variants will also be investigated. Finally, the application of the indole (spiro)cyclization reaction to the total synthesis of aspidospermidine will showcase the utility of the developed chemistry. This multidisciplinary Fellowship, based on high-quality and novel research at the University of Oxford, one of the top-research centres worldwide, will complement Dr Xie’s skills and knowledge to improve his career possibilities and at the same time, Dr Xie’s experience in creating catalytically active transition metal complexes will be critical for developing chiral versions of the iridium catalyst during the development of a catalytic asymmetric version of the reductive cyclization cascade.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'A scientific approach to nature' (SCINATFEAST) under Sixth Framework.

assistant: **Objectives**

Tempus Public Foundation as coordinator, Mindentudás Egyeteme Tudományos Kht., Eötvös Loránd University, the Budapest University of Technology and Economics and Széchenyi István University, Gyor as participants undertake the organisation of the Hungarian Researchers' Night. The event is part of a pan-European initiative which takes place all over the continent on 22 September, 2006.The Europe-wide festival series aims at emphasizing that researchers live 'among us'. The Hungarian event will focus on science and researchers' career specifically in the fields of natural sciences and environment protection. We aim to raise a deeper awareness in environment protection issues as well as to bring science and scientists closer to the society by presenting science in a user-friendly way and providing easy access to the 'habitat' of science.To obtain our objectives we wish to involve the public in a wide range of various activities. These include hands-on experiments at different HEI sites; scientific lectures and demonstrations; laboratory and cave visits; geophysical experimentation and astronomical observation on the Danube; the challenge of an on-line quiz series; creative competitions for students; inventions of very young scientists; exhibitions of 'green' organisations; researchers' show and a researchers' pub The professional background of each organiser (a national bureau for EU grants, a science media actor, 3 HEIs) ensures that the activities will be efficiently co-ordinated and both the 'serious' and 'fun' activities will display a high standard of quality. We foresee that though the activities will take place in Budapest and Gyor the outreach of the event will be way wider as via the Internet and the television most of Hungary will be covered.We expect an increased
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Towards Game-changer Service Operation Vessels for Offshore Windfarms' (NEXUS).

assistant: **Innovation**

NEXUS will develop and demonstrate novel, beyond state of the art, specialised vessel and logistics for safe and sustainable servicing of offshore wind farms. NEXUS includes: simulation, model testing, consideration of the most suitable construction and production principles for small series or one off vessels of this type. Key aspects of NEXUS include environmental impact assessment, cost estimation as well as both the marketability (technology push), and the cost effectiveness of the offshore operations concerned (demand pull). The project will develop the concepts and validate on a demonstrator at a technology readiness level (TRL) 5 with the overall aim to reduce the marine logistics cost of offshore wind turbine maintenance by 20% compared to current practices. In addition NEXUS will enable the increase the professional skills of workers and the capability of European industry and in particular SMEs within the marine and maritime sectors to develop and commercialise specialised vessels and related technology, and will support European growth and employment through development of a blue economy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'The Epistemic Role of Scientific Idealization'.

assistant: **Objectives**

In the contemporary philosophy of science, attention has been increasingly paid to the role of idealization in providing objective and genuine knowledge about natural phenomena, that is, knowledge that ascertains their mind-independent reality and also helps us to understand why they occur in the way they do. The main objectives of the present project are (1) the critical evaluation of the current views about scientific idealization that attempt to account for this role, and (2) the proposal of a new position about the ways in which idealization serves objectivity and understanding in physics, a position that overcomes the shortcomings of the current views.With regard to (1),  I focus on two recent influential attempts to accommodate idealization within a causal account of scientific explanation, by Michael Strevens and James Woodward, as well as on one equally recent and influential attempt, by James Ladyman and Steven French, to justify the view that objective knowledge requires that the structure of a theory be invariant.With regard to (2), I build on the work of David Hilbert in the foundations of mathematics and physics. My goal is to explain in what sense idealization may be considered capable of providing objective and genuine scientific knowledge, without revealing the causes of natural phenomena, and without adverting to the notion of structural invariance.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Material Science Innovation for Accelerated, Sustainable and Safe Implementation of Carbon Capture and Storage' (MISSION-CCS), addressing dissemination and exploitation.

assistant: **Impact**

MISSION-CCS presents a timely and unique doctoral network designed to deliver the next generation of highly trained researchers and entrepreneurs in the field of material science, specifically focused towards accelerating implementation of carbon capture and storage CCS technologies worldwide and ensuring the sustainable and safe operation of existing and future CCS systems.The training network combines unique experimental system design and modelling approaches, state-of-the-art analytical technologies and techno-economic analysis to deliver a new generation of researchers and entrepreneurs. The programme of research training centres of delivering Doctoral Candidate Researchers (DCRs) with world-leading technical expertise in material science and engineering relevant to the entire CCS process. MISSION-CCS ensures that the subject-specific technical knowledge of each DCRs is under-pinned by inter-sectorial knowledge whilst also promoting wider innovation skills and relevant training on the techno-economics of CCS, developing experts with breadth of knowledge.A central aim of the network is to forge a strong cohort culture, by ensuring that peer-to-peer learning and mutual support become the norm, in order to enhance experience. Research-led training activities are strengthened through a dynamic and interactive education based programme delivered by an internationally renowned consortium of academics and industrialists with complementary skills. As part of the training programme, subsequent to an introduction to CCS systems and the specific material science challenges, DCRs will gain knowledge of system design and optimisation, state-of-the-art analytical methods, theoretical modelling, techno-economics, and understand the challenges of exploiting their research. They wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'The equilibrium exchange rate', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The concepts of currency overvaluation and undervaluation imply a willingness to make judgments about where an equilibrium exchange rate lies.  The main objective of the project is an evaluation of equilibrium exchange rates. This will involve an extension of Williamson's concept of the Fundamental Equilibrium Exchange Rate. This concept will be extended in two directions. First, statistical analysis of the long-run properties of the economies of interest will be undertaken. Second, an analysis of the objectives of the authorities and the targets of the private sector will be undertaken. The former extension will use multivariable cointegration analysis, while the later will involve a study of the effects of governments debt stocks and private sector wealth accumulation on the equilibrium current account and exchange rate.  Being able to make sensible estimates of equilibrium exchange rates is the key importance to rational, outwarded-oriented macroeconomic management.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'ColorSensing Tracking true colors' (2021-2027).

assistant: **Concept**

Reducing food waste is an issue that concerns us all; the ColorSensing company was born to contribute to this urgent global call by developing an affordable smart packaging solution to help packaged food manufacturers and retailers reduce waste and ensure the quality and safety of their products. Thanks to its CEO Mª  Eugenia Martín, what began as an idea in the research laboratory of the University of Barcelona has already transcended into a minimally viable product, which consists of the use of a QR label (Smart label) with integrated Smart inks that are capable of to determine the actual state and conditions of packaged foods. Users can read these smart labels simply by taking a photo, and with our Smart reading program developed with our algorithm, they will receive quantified information about the real state of the food they intend to consume. All the elements that this innovation includes were created and developed by our company, offering an easy-to-use solution for the food packaging industry, which does not have the necessary technology to receive information about the quality and real state of conservation of food packaged throughout its useful life. As a result, we can improve the efficiency of the supply chain and reduce the costs involved in not having constant control of the real state of the food. Our product has already been tested with excellent results thanks to our participation in the Vegalsa project, where we monitor the condition of the meat with our QR labels and through an App developed by us in a supermarket chain. We offer a solution framed within the EU standards regarding the food packaging industry, where a medium-sized manufacturer can save more than €300,000/year by using our product. Furthermore, consuming packaged food with our integrate
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Advanced genomics instruments, technology and methods for determination of transcription factor binding specificities; applications for identification of genes predisposing to colorectal cancer' in the context of a Sixth Framework call.

assistant: **Objectives**

Determination of the sequence of the human genome, and knowledge of the genetic code through which mRNA is translated have allowed rapid progress in identification of mammalian proteins. However, less is known about the molecular mechanisms that control expression of human genes, and about the variations in gene expression that underlie many pathological states, including cancer. This is caused in part by lack of information about the 'second genetic code' - binding specificities of transcription factors (TFs).Deciphering this regulatory code is critical for cancer research, as little is known about the mechanisms by which the known genetic defects induce the transcriptional programs that control cell proliferation, survival and angiogenesis. In addition, changes in binding of transcription factors caused by single nucleotide polymorphisms (SNPs) are likely to be a major factor in many quantitative trait conditions, including familial predisposition to cancer. We aim to develop novel genomics tools and methods for determination of transcription factor binding specificity. These tools will be used for identification of regulatory SNPs that predispose to colorectal cancer, and for characterization of downstream target genes that are common to multiple oncogenic TFs. Specific aims: 1. To develop novel high throughput multiwell-plate and DNA-chip based methods for determining TF binding specificity 2. To experimentally determine the binding specificities of known cancer-associated TFs 3. To computationally predict and experimentally verify elements regulated by these TFs in genes essential for cell proliferation. 4. To develop a SNP genotyping chip composed of SNPs that affect the function of TF-binding sites conserved in mammalian species. 5. To use this chip for genotypin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Innovative operational UAV integration'.

assistant: **Concept**

The driving force behind creating the INOUI project and to answer the above call is stemming from the fact that no ongoing European project focuses on the crucial matter of Unmanned Aerial Vehicles (UAVs). Regardless of the fact that i.e. drones are already furrowing the skies, albeit either at a very low altitude, or in segregated airspace due to their mostly military nature, the integration in the non-restricted airspace is left aside. In particular, the topic UAV is almost totally absent from SESAME and its high-level Definition Phase (Phase I) which, given the size of the project and the impact it is going to have on the ATM community in the years to come. INOUI aims at complementing SESAME to compensate for this flaw of leaving out UAVs. This will be achieved by developing documents providing a roadmap to the future of UAVs in the context of the ever changing ATM environment.