RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Stereo and enantioselective synthesis of an anti-cancer agent modelled after the neocarzinostatin pharmacophore' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

The natural products neocarzinostatin, esperamicin, calichemicin, dynemicin, and Research objectives and content kedarcidin represent so of the most promising leads for the development of potent anti-cancer agents. However, none of these compounds can be administered as such because they are strong cell poisons. Therefore, a challenging task in medicinal chemistry today is to synthesize analogs of these compounds which conserve their striking antitumor activity but are free from adverse side effects. The project proposed by Prof. Bruckner will contribute to solving this task by developing a synthetic route to a bioactive structural analog 1 of the least investigated member of these natural products, i.e. to the pharmacophore 2 of neocarzinostatin. Me> OMe Ring strain is decreased and hence stability increased in 1 vs. 2. Almost all other structural features of 2 are preserved in 1, except the sugar moiety. It is therefore expected that thiols react with compound 1 initially in very much the same way as very recently discovered in the case of 2. But importantly, other than 2 compound I should subsequently deliver - as specified in the detailed description of this work biradicals which cleave DNA andy destroy cancerous cells thereb. In-vivo and invitro DNA-cleavage essays will be performed in collaboration with specialists. Training content objective, benefit and expected impact) The goal of my postdoctoral stay is to synthesize the designed pharmacophor 1. The intended work will therefore deepen my acquaintance with modern synthetic methodology. This work will also expose myself for the first time to the particular difficulties of performing a true multistep synthesis. The prospect to synthesize with my own hands a compound which might even become an antitumor antibiotic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'One-Stop-Shop Open Access to  Photonics Innovation Support for a Digital Europe' under Horizon 2020.

assistant: **Concept**

PhotonHub Europe will establish a single pan-EU Photonics Innovation Hub which integrates the best-in-class photonics technologies, facilities, expertise and experience of 53 partners from all over Europe, including the coordinators of EU pilot lines and local photonics hubs representing 18 regions, as a one-stop-shop solution offering a comprehensive range of supports to industry for the accelerated uptake and deployment of photonics. PhotonHub will provide European companies, in particular “non-photonics” SMEs and mid-caps that are first users and early adopters of photonics, with open access and guided orienteering to the following key support services: training and upskilling opportunities within PhotonHub’s Demo and Experience Centres throughout Europe and enhanced by digital tools for online learning; “test before invest” innovation support capabilities to engage with companies on highly collaborative Innovation Projects aimed at TRL acceleration from prototyping (TRL3-4) to upscaling (TRL5-6) to manufacturing (TRL7-8), and complemented by targeted business and IP advisory supports; and support to find investment through investment-readiness coaching and investor match-making organised in collaboration with major regional and European venture fora and deep tech Investor Days. PhotonHub will uniquely support cross-border innovation activities of European companies, while simultaneously working closely with the local photonics hubs to develop and roll out best practices of the “lighthouse” regions for ongoing regional financial support of SME innovation activities and to support the creation of new innovation hubs covering most regions of Europe. Finally, PhotonHub will fine-tune and implement its business plan for long-term sustainability in the form of the PhotonH
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Cavity Quantum Optomechanics: Exploring mechanical oscillators in the quantum regime'.

assistant: **Concept**

In recent years the development of cavity otomechanical coupling has enabled to achieve the quantum regime of mechanical systems in an experimental setting. The present proposal building on these developments and demonstrate mechanical oscillators ability as a quantum technology. It seeks to investigate and utilize coherent coupling of ground state cooled mechanical oscillators for storage of single photons in mechanical oscillators, explore backaction evading measurements, explore quantum dissipation due to two level systems, demonstrate novel transducers and explore an microwave to optical quantum link based on effective optomechanical interactions. The applicant has laid the basis for these objectives within the framework of an ERC Starting Grant (call 2007) that demonstated the methods to achieve the quantum regime of mechanical oscillator. The present proposal seeks to use the ERC Advanced Grant to directly build on the advances of this project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Innovative Low-Mass Tanks for a Low-Cost, Low-Carbon European Micro-Launch Vehicle'.

assistant: **Concept**

Small satellites (smallsats) are playing an increasingly significant role in space. Smallsats currently fly to space via ridesharing – taking spare capacity on a large launcher. Rideshare has numerous issues, including lack of availability, severe launch delays, and unsuitable orbits. Orbex is developing an EU-based orbital micro-launch vehicle with a uniquely innovative advantage that eliminates the issues of rideshare and mitigates the cost of a dedicated launch for smallsat operators. The vehicle exploits the properties of dual-cryogenic propellants to create an innovative, lightweight, low-cost tankingarrangement that reduces the inert mass of the launch vehicle by as much at 30% over traditional designs, and enable the world’s first environmentally-friendly rocket fuel strategy, with a 90% reduction in environmental impact. The small satellite launch market is well established and growing rapidly. The market for smallsat launch services is projected to grow US$2.52B p.a, by 2022, a CAGR 23.2%. The benefits of developing this tanking system for a European micro-launch vehicle include:- • Lowering cost of space access, including logistics/integration• Reduced delay in time-to-market• Enabling faster revenue generation for smallsat business modelsOrbex staff have designed & realized a prototype tank, and subsequently drafted patents for the technology. The tank was instrumented, hydrostatically pressure-tested and then used to prove the concept in cryogenic conditions. The objective of this SME Instrument Phase 2 project is to build on a prior SME Instrument Phase 1 feasibility study of the materials, suppliers and production processes required to implement this novel fuel tank concept using European materials and techniques at full scale. This Phase 2 project allow a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'TErrestrial Resilience and RestorAtion Strategies for (semi) Arid and Fragile Ecosystems through a multi-actor approach' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

TERRASAFE is a pioneering initiative envisaging to empower local communities in southern Europe and northern Africa to successfully face the escalating challenges of desertification through the adoption of nature-based, social and technological innovations. TERRASAFE’s vision will be operationalized in 5 pilot areas that share a high vulnerability to desertification but, simultaneously, represent the 4 main types of desertification (vegetation decline, soil degradation, water scarcity, and depopulation) and strongly contrast in socio–cultural-ecological circumstances. This vision is supported by a transdisciplinary consortium, ranging from universities to SMEs commercially exploiting innovations.TERRASAFE’s vision is implemented through a multi-actor approach covering all WPs, in particular by setting up 5 partnerships in the 5 pilot areas. In a co-creation process, these partnerships will then (i) define their visions on building desertification resilience and plan their ensuing TERRASAFE work; (ii) map and analyze past and ongoing desertification, identifying hotspots; (iii) evaluate and demonstrate innovations at these hotspots, comparing them with current and traditional/organic practices; (iv) elaborate policy recommendation for the wider uptake of the TERRASAFE-certified innovations, both within and beyond the pilot areas, taking into account lessons learnt from past and ongoing policies against desertification; (v) share their TERRASAFE’s experience with the other areas, other desertification-prone communities and the general public. The consortium will support the partnerships by providing not only harmonized frameworks for each activity but also advice on adapting these frameworks to their specific needs. Finally, the SMEs will provide a wide offer of innovatio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Study of high frequency vibration induced steady wetting and of high frequency vibration induced nanoparticle assembly for molecular electronics' (SBL).

assistant: **Concept**

One of the main goals of scientific research nowadays is to develop methods to prompt and control natural processes at nanometre and micrometre resolutions for advancing technological capabilities at such length resolutions. Many corresponding examples exist, from which we bring the field of molecular electronics; although advanced remarkably in recent years, this field lacks cheap and efficient integration methods for fabricating nano- and micro-scale complex and inter- and intra-connected artificial structures made of large quantities of electronic building-blocks such as gold nano-particles, carbon nano-tubes, polymeric semiconductor wires, and other molecules of electronic viability 2-5. The PI is proposing to study the physics associated with translating complex electronic signals, comprising MHz to GHz frequencies, to uniquely determined micron and submicron non linear flow patterns, capable of integrating particulate suspensions into structures at related resolutions; flow is invoked through the intermediate step of translating electronic signals to packets of Rayleigh surface acoustic waves (SAWs) atop a piezoelectric SAW device in contact with particle suspensions that undergoes attachment/detachment processes according with the spatial strength and directionality of the flow and attraction/repulsion DLVO forces between the particles themselves. The PI will, foremost, elucidate the physics of SAW induced complex micron and submicron stable and unstable stagnant flow patterns in microchannels, and will further study stability of multiple particle suspensions, crumbed into patterns by flow, using principles of colloid science and the physics of particle interactions. This proposed study thus suggests a new approach for managing and controlling natural processes i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'INDUSTRIAL PRODUCTION OF ELECTRIC POWER BY UTILISATION OF PURIFIED LOW ENERGY GAS COMING FROM REFUSE DERIVED FUEL', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The aim of the project is to demonstrate the economic and technical viability of the production of electricity via the gasification of Refuse Derived Fuel (RDF). A 3.5 MWe power station was built by the municipalities in the Chianti region to be fuelled by RDF produced locally. In the plant, the RDF is gasified to produce a Low Energy Gas (LEG) which is used to fire a boiler and raise steam to drive a turbine. Although the plant has been operated with some success, unexpected fouling of the boiler has occured. This has caused a significant reduction in the expected operating hours of the power station and the resultant loss of electricity production has had a negative impact on the economics of the project. It is proposed to design, construct and operate a second combustion line between one of the existing two gasifiers and the steam turbine. The new line will incorporate a novel combination that the new clean-up system for the gas will improve the availability of the power plant and thus restore the economic viability of the power station.The results of the project will be evaluated in the following ways :- performance of the steam production process, in terms of the reliability and availability of the boiler, including internal inspections to check for signs of fouling corrosion.- reliability and availability of the de-dusting and filter equipment.- measurement of the quality of the gas before and after cleaning.- measurement of the quality of the flue gas to check to effect of gas clean-up on stack emissions.- economic performance of the new gas clean-up system in terms of operation and maintenance costs.- economic perfromance of the power generation plant in terms of the increase in electricity production.The results of the project will be disseminated via the publi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Development of a durable and energy-efficient baking plate' (Thermoback), addressing dissemination and exploitation.

assistant: **Impact**

In average Europeans consume 650kg of bread per person per year. To answer the increasing demand in term of variety and quality, both industrial and craft bakers need to improve qualitative, economic and energetic process efficiency. The current baking plates in the ovens are made from concrete  and are energetic inefficient, having a low life expectancy and reduce the quality of the products.  Conrad Liphard & Söhne has developed a new and innovative baking plate from ceramic with outstanding baking characteristics, Thermoback. This development has demonstrated energy-efficient, durable, and heat conduction improvement. The plate is made of a mixture of calcium oxide, aluminum oxide, as well as various additives as silicon carbide which helps to reach optimal heating values. Thermoback demonstrated: about 30% of energy savings, high stability of the plates (firm, unbreakable plates), time savings up to 25%, and a higher product quality.  Liphard & Söhne wants to introduce thermoback technology into the market, and  therefore, with the requested fund, a feasibility study as well as a market research will facilitate the product’s entry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Helically-Locked π-Conjugated Oligomers and Polymers with Tunable Twist' (PolyHelix) under Horizon 2020.

assistant: **Objectives**

The performance of organic electronic materials is strongly dependent on their conformation. Twisting these materials out of planarity induces chirality and thus results in new electronic, magnetic, and optical properties with increasing numbers of applications as non-liner optical devices, spin filters, and magneto-optical devices. However, the effect of twisting is poorly understood, as it is difficult to isolate from other factors. Moreover, twisting often comes at the expense of π-conjugation, resulting in inferior device performance.Using a novel approach, I propose to address this challenge by introducing a new family of helically-locked organic electronic materials, oligomers and polymers, in which the twist of the π-conjugated backbone can be finely tuned. This will allow us to monitor and understand the effects of twisting on the electronic, optical, and magnetic properties of organic electronic materials. Unlike most chiral conjugated materials, the proposed approach allows the formation of polymers with a tunable twist, helical backbone chirality and strong π-conjugation, a combination often difficult to obtain.Following our preliminary findings, which successfully demonstrated the helical locking of small acene units to a specific twist angle, my team will focus on five ambitious projects: 1) Synthesis of extendable twistacene units. 2) Synthesis of helically-chiral oligomers polymers with tuneable twist. 3) Study of the effect of twisting on the charge and energy transfer processes. 4) Synthesis of open shell twisted acenes. 5) Understanding the effect of twisting on the magneto-optical properties and chiral-induced spin selectivity. The successful introduction of the abovementioned twisted backbones will allow us to understand the influence of molecular st
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Detection Technologies, Terrorism, Ethics and Human Rights' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

DETECTER  aims at increasing the compliance of counter-terrorism with human rights and ethical standards in the rapidly changing field of detection technologies. The project addresses the increasingly international character of counter-terrorism, the increasing use of informal mechanisms for altering law-enforcement practice to meet the threat of terrorism, and the great variety of detection technologies and their uses. The partners agree on the need for human rights standards to be informed by dialogue with both manufacturers of detection technology and law-enforcement officials directly involved with counter-terrorism who use this technology and influence the development of products. The project combines applied ethical and legal research with this dialogue in order to affect the design and use of products, to make ethical and legal research better informed, and to innovate conceptually in a field that is developing with great speed.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Building Next-Generation Computational Tools for High Resolution Neuroimaging Studies' (BUNGEE-TOOLS) targeting Horizon 2020.

assistant: **Abstract**

Recent advances in magnetic resonance (MR) acquisition technology are providing us with images of the human brain of increasing detail and resolution. While these images hold promise to greatly increase our understanding of such a complex organ, the neuroimaging community relies on tools (e.g. SPM, FSL, FreeSurfer) which, being over a decade old, were designed to work at much lower resolutions. These tools do not consider brain substructures that are visible in present-day scans, and this inability to capitalize on the vast improvement of MR is hampering progress in the neuroimaging field.In this ambitious project, which lies at the nexus of medical histology, neuroscience, biomedical imaging, computer vision and statistics, we propose to build a set of next-generation computational tools that will enable neuroimaging studies to take full advantage of the increased resolution of modern MR technology. The core of the tools will be an ultra-high resolution probabilistic atlas of the human brain, built upon multimodal data combining from histology and ex vivo MR. The resulting atlas will be used to analyze in vivo brain MR scans, which will require the development of Bayesian segmentation methods beyond the state of the art.The developed tools, which will be made freely available to the scientific community, will enable the analysis of MR data at a superior level of structural detail, opening completely new opportunities of research in neuroscience. Therefore, we expect the tools to have a tremendous impact on the quest to understand the human brain (in health and in disease), and ultimately on public health and the economy.