RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Advanced Spectroscopy and Spectrometry for Imaging Metabolism using Isotopically-Labeled Endogenous Substrates' in the context of a Horizon 2020 call.

assistant: **Objectives**

A technological revolution is currently taking place making it possible to noninvasively study metabolism in mammals (incl. humans) in vivo with unprecedented temporal and spatial resolution. Central to these developments is the phenomenon of hyperpolarization, which transiently enhances the magnetic resonance (MR) signals so much that real-time metabolic imaging and spectroscopy becomes possible. The first clinical translation of hyperpolarization MR technology has recently been demonstrated with prostate cancer patients.I have played an active role in these exciting developments, through design and construction of hyperpolarization MR setups that are defining the cutting-edge for in vivo preclinical metabolic studies. However, important obstacles still exist for the technology to fulfill its enormous potential.With this highly interdisciplinary proposal, I will overcome the principal drawbacks of current hyperpolarization technology, namely: 1) A limited time window for hyperpolarized MR detection; 2) The conventional use of potentially toxic polarizing agents; 3) The necessity to use supra-physiological doses of metabolic substrates to reach detectable MR signalI will develop a novel hyperpolarization instrument making use of photoexcited compounds as polarizing agents to produce hyperpolarized solutions containing exclusively endogenous compounds. It will become possible to deliver hyperpolarized solutions in a quasi-continuous manner, permitting infusion of physiological doses and greatly increasing sensitivity. I will also use a complementary isotope imaging technique, the so-called CryoNanoSIMS (developed at my institution over the last year), which can image isotopic distributions in frozen tissue sections and reveal the localization of injected substrates and t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'EeB Cluster Activities Coordination Action' to be submitted under Horizon 2020.

assistant: **Abstract**

EeB-CA2 initiative is to provide the right set of instruments supporting technology-clustering and geo-clustering upon the whole set of EeB PPP EC-funded projects related to energy efficiency in the built environment, with the following primary ambition: to enhance and rationalise coordinated and broader dissemination, technology transfer and future exploitation activities of clustered projects, so as to help them better promoting and marketing their achievements and deliverables.


**Keywords:** clustering technology geographical  energy efficient buildings  transfer dissemination
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'European organic solar cell initiative' (1994-1998).

assistant: **Concept**

Objectives The aim of the project is to develop solar cells using organic materials. The general goal is the determination of both the materials and the device structures that are the best suited for photovoltaic application. An important point is the overall efficiency of solar energy conversion and a particular attention is to be paid to the stability of the device. From the results of the project, technological routes of potential industrial interest for fabrication of organic solar cells will be defined. Technical approach Technical interest for organic semiconductors is motivated by recent significant advances. In particular, Japanese laboratories have published break-through photovoltaic conversion efficiencies of several per cent in multi-layer devices fabricated under ultra-high vacuum conditions. Economically, for low consumption devices, photovoltaic energy appears far less expensive than any remote electric-network connection. A reduction of photovoltaic energy cost with respect to amorphous silicon devices may boost the market. Our approach consists of a comparative evaluation of two competing technologies : solution deposition of polymers and vacuum deposition of low molecular-weight materials. Scientific objectives are the development of an insight into the physics of the device specific to the photovoltaic application, the identification of the overall efficiency as well as stability-limiting processes during all steps of photocurrent and photovoltage generation, the correlation to chemical and physical structure as molecular engineering rules. Technical objectives are the fabrication of stable solar cell devices operating with typically 4% efficiency as a proof of principle to assess the interest in pursuing organic materials further, towards improved de
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Microfluidic assay for rapid multiplexed detection of bacterial urinary tract infections'.

assistant: **Concept**

We propose to develop a microfluidic chip-sized assay for low-cost, sensitive, rapid, and multiplexed detection of bacteria in urine.  We aim to reduce bacterial diagnostic time from the current standard of 1-3 days to several minutes.  The device will have application to both conventional clinical microbiology laboratories and point-of-care settings, and will eliminate dependence on highly trained operators.  We propose to use isotachophoresis (ITP) to extract and concentrate the bacterial signature 16S ribosomal RNA directly from urine samples, and detect and quantify its presence using a set of complementary fluorescent probes (molecular beacons) on a low-cost microfluidic chip.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Static and dynamical properties of electron-phonon systems - one-electron versus many-electron picture'.

assistant: **Innovation**

We propose two complementary approaches in understanding coupled electron-phonon systems. The first one is based on extensive numerical studies of the full time evolution of one or two electrons coupled with a lattice. Our previous results clarify the role of coupling, adiabatic parameter, initial electronic configuration, discreteness, and disorder in the problem of polaron formation and demonstrate the existence of novel, long- lived metastable states. We will extend these studies to include bipolaron formation, higher dimensions, application of external field, quantum and thermal fluctuations. The second approach is based on rigorous mathematical techniques and numerical methods for the many - electron problem in the adiabatic Holstein model with or without magnetic field. They will be applied in the study of bipolaronic - polaronic ground state distributions in any dimension and will be extended to include temperature, orbitar response, anisotropy, and other physical models. The results are expected to have far reaching consequences in the field of transport properties of solids and elucidate a lot of aspects of the mechanism of high critical temperature superconductivity.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Micro-Fat Tissue on Chip'.

assistant: **Objectives**

Human fat tissue has evolved to serve as a major energy reserve. An imbalance between energy intake and expenditure leads to an expansion of adipose tissue. Maintenance of this energy imbalance over longer times leads to obesity and metabolic disorders such as type 2 diabetes, for which clinical cures are not yet available. Adipocytes are the main cell type within the adipose tissue and can be divided into white, beige, and brown subtypes. White adipocytes store and mobilize energy, whereas beige and brown adipocytes store and burn energy during cold exposure to generate heat. An attractive strategy to restore the energy imbalance and treat obesity is to activate or increase the number of beige adipocytes in white adipose tissue. The main research obstacles affecting our ability to induce beige adipocytes is our lack of laboratory test systems recapitulating the microenvironmental conditions of the adipose tissue. Therefore, this research project aims to develop adipose tissue models outside organisms in sizes of micrometers for studying the differentiation of human inducible pluripotent stem cells (hiPSCs) into mature adipocytes. For assembly of the micro-fat tissues, we combine microfluidic and bioprinting technologies. In particular, the integration of micro-fat tissue on microfluidic chip platforms will be exploited to dynamically control the chemical, cell architectural, and mechanical microenvironment of hiPSCs incorporated in the micro-fat tissue. With novel single-cell-resolution in situ detection systems, we will aim to reveal, which microenvironmental stem cell niche factors are required to differentiate hiPSCs into metabolically active beige adipocytes. The acquired experimental data will help to mechanistically understand the role of natural stem cell niches
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Building Intelligent Positive Energy Districts' (BIPED) under Horizon Europe.

assistant: **Objectives**

Positive clean Energy District’s (PED) are a key building block in the future energy paradigm for carbon-neutral cities and communities. With the rise of modern technology, local digital twins – the digital representations of a functional territory combining low- and high-velocity data with dynamic models – play a significant role in PED development and the scaling of it, supporting decision makers and planners in taking informed decisions towards a sustainable future. However, focusing narrowly on energy and mobility topics confined to the traditional sectors, digital twins for PEDs currently lack representation of significant aspects such as social, economic, and environmental properties, and hence, draw only part of the picture of a district or a city. Limited by data availability and lacking awareness of existing data, this shortcoming in digital twin modelling for PEDs leads to suboptimal decisions, impacting negatively ambitious efforts of sustainable development in cities and communities. This becomes even more clear when reflecting on the scalability issues across the 80.000 municipalities in the EU27: As highly complex entities, cities and communities differ in their physical, social, economic and even cultural structures, making it challenging to replicate PEDs in a trivial way across Europe.The BIPED project demonstrates how to overcome these barriers in a simple yet highly efficient manner that works everywhere by answering three key questions to push PEDs to the next level: wide deployment.Three key questions needs to be addressed to push PEDs to the next level:•How can digital twins be extended to refine a district’s profile representation, guiding PED design and demonstrators?•How can the quantitative collection of soft data support the advancement in dig
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Understanding the mass scales in nature' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The experimental results of the first run of the Large Hadron Collider lead to the discovery of the Higgs boson but have not confirmed the dominant theoretical paradigm about the naturalness of the electro-weak scale, according to which the Higgs boson should have been accompanied by supersymmetric particles or by some other new physics able of protecting the Higgs boson mass from quadratically divergent quantum corrections.While the second LHC run is going to explore physics at higher energies in the next years, it is now the right moment to explore and develop new non conventional ideas about the origin of  mass scales in nature and in particular of the electro-weak scale.  Indeed, new theoretical ideas prompted by the fact that the standard paradigm is challenged by experiments, have been emerging in the past 1-2 years and are acquiring interest.  Furthermore, in view of the large backgrounds unavoidably present at the Large Hadron Collider,  unexpected discoveries could be delayed or even missed if experimentalists are not searching in the right direction.The experimental signatures of the new non-conventional models need to be identified now.Research performed by the PI and by the senior team members shows that concrete progress  can be achieved in developing new non-conventional ideas about how the electroweak scale and the gravitational Planck scale can be dynamically generated with a vastly different ratio, as observed in nature. However, dedicated funding is needed for younger researches that want to explore such directions outside the mainstream.  The main goal of this project is developing such new ideas and identifying their experimental signals.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Neural mechanisms of multisensory perceptual binding' to be submitted under Horizon 2020.

assistant: **Abstract**

Sensory perception involves the discrimination and binding of multiple modalities of sensory input. This is especially evident in the somatosensory system where different modalities of sensory input, including thermal and mechanosensory, are combined to generate a unified percept. The neural mechanisms of multisensory binding are unknown, in part because sensory perception is typically studied within a single modality in a single brain region. I propose a multi-level approach to investigate thermo-tactile processing in the mouse forepaw system from the primary sensory afferent neurons to thalamo-cortical circuits and behaviour.The mouse forepaw system is the ideal system to investigate multisensory binding as the sensory afferent neurons are well investigated, cell type-specific lines are available, in vivo optogenetic manipulation is possible both in sensory afferent neurons and central circuits and we have developed high-resolution somatosensory perception behaviours. We have previously shown that mouse primary somatosensory forepaw cortical neurons respond to both tactile and thermal stimuli and are required for non-noxious cooling perception. With multimodal neurons how, then, is it possible to both discriminate and bind thermal and tactile stimuli?I propose 3 objectives to address this question. We will first, perform functional mapping of the thermal and tactile pathways to cortex; second, investigate the neural mechanisms of thermo-tactile discrimination in behaving mice; and third, compare neural processing during two thermo-tactile binding tasks, the first using passively applied stimuli, and the second, active manipulation of thermal objects.At each stage we will perform cell type-specific neural recordings and causal optogenetic manipulations in awake and beh
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Mapping and monitoring coral Reefs using satellite image data and texture analysis methods' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Coral reefs are a globally significant natural and economic resource and are declining in condition throughout the world. Managing such diverse ecosystems is a challenging task.The ability to measure and monitor the health or condition of a coral reef is a fundamental international need both among a variety of government resource management agencies and among user groups such as the fishing and tourism industries and local communities whose livelihood depends on a healthy reef ecosystem.Remote sensing technology allows us to extract biophysical information on coral reefs in a non-intrusive and relatively inexpensive manner. The recent commercial availability of high-resolution remote sensing image data has provided the reef research community with a wealth of information.Up to now, the majority of image processing techniques developed for the purpose of coral reef mapping and monitoring have concentrated on the use of spectral (reflected sunlight) information, without giving much consideration to the spatial context or texture (pattern of reef features) of the pixels.Preliminary studies by the hosts have produced promising results on the use of texture-based methods for extracting biophysical attribute (e.g. coral type and condition) information from high-resolution satellite image data sets of coral reefs.The purpose of this research project is to bring together the digital image processing and texture analysis expertise of the researcher with the extensive environmental remote sensing and management skills of the two hosts.The project will enable the researcher to develop a unique set of skills and contribute to an important global effort to develop an integrated management programme for the mapping and monitoring of coral reefs worldwide.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Cryogenic Hypersonic Advanced Tank Technologies' to be submitted under Seventh Framework.

assistant: **Abstract**

Topic: Cryogenic propellant management and advanced tank design for hypersonic and advanced future aviation systemsIn future aviation and particularly in hypersonic systems new propellants will be used, such as liquid hydrogen, liquid methane and possibly even liquid oxygen. These systems will require complex technology, ultra light-weight, and reusable propellant tank systems. Challenging technological developments are required for such systems. New materials and design concepts are required such as fibre composites in order to reduce the tank weight and to increase the structural performance. Propellant management is imperative for achieving reliable and efficient vehicle operation. The sloshing of cryogenic fluids close to their boiling conditions in tanks of horizontal take-off vehicles is not yet mastered.Proposed work tasks are:• Design, manufacturing, and tests of 4 different scaled cryo-tanks in CFRP material including and w/o liner.• Screening of future cryogenic insulation systems not only lightweight and long lasting but also resistant to the high thermal gradients experienced in hypersonic flight. New cryogenic insulation concepts and materials will be addressed, such as e.g. Aerogels.• The following propellant management technologies will be studied by simulation or experiment: tank pressurization, fuel location/retention, horizontal sloshing, analytical and experimental study of stratification, nucleation, and boiling in cryogenic fuel tanks subject to surface heat transfer.• Design of a small ceramic heat exchanger to assess the safe generation of gaseous propellants used for improved tank pressurization, attitude control and cabin oxygen supply. A prototype Rankine cycle cabin air-conditioning system, utilising a cryogenic working fluid is designed.• All