RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Empowered Participation through Ideating Cultural Worlds and Environments: youth imagining, creating and exchanging cultural values and heritage through game-making' under Horizon Europe.

assistant: **Concept**

EPIC-WE introduces cultural game jams, culture- and value-sensitive game-making and games through and for culture as a novel approach to empower young people as co-creators of European culture and shapers of their own futures in society, cultural institutions (CHIs) and creative industries (CIs). The backbone of the project is the EPIC-WE helix ecosystem - a transferable framework where youth, CHIs, CIs and higher education institutions (HEIs) cooperate as actors in the ecosystem. Together EPIC-WE engage in cultural games jams to create games through and for culture inspired by cultural heritage. The framework explores the potentials of this approach as a method for strengthening European values, belonging and cultural participation. Through game-making activities, EPIC-WE will equip youth with cultural-creative imagination and competencies to face societal challenges with curiosity, creativity, agency and imagination – what we call Empowered Participation. The project is carried out as an ambitious Design-Based Research and Innovation (DBR) action across three European sites, where EPIC-WE ecosystem actors co-create, and through this, develop, implement and evaluate the proposed framework. The validated DBR innovations are presented as accessible resources that enable organisations across Europe to replicate the EPIC-WE ecosystem, formats, and methods. Through extensive research, capacity building and policy advocacy activities, EPIC-WE will ensure that the project’s results reach a wide range of European CHI, CI and HEI actors, including the game industry, civil society organizations and youth. The consortium is in itself a helix ecosystem, bringing together leading research, cultural and creative sector organisations with multidisciplinary excellence in DBR, particip
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Illustrative Visualization of Processes' to be submitted under Seventh Framework.

assistant: **Abstract**

The central focus the research is to understand visual abstraction. Understanding means 1. to identify meaningful visual abstractions, 2. to assess their effectiveness for human perception and cognition and 3. to formalize them to be executable on a computational machinery. The outcome of the investigation is useful for designing visualizations for a given scenario or need, whose effectiveness can be quantified and thus the most understandable visualization design can be effortlessly determined.The science of visualization has already gained some understanding of structural visual abstraction. What has not been given sufficient scientific attention to, is advancing the understanding of procedural visual abstraction, in other words investigating visual means that convey what things do or how things work. This missing piece of knowledge would be very useful for visual depiction of processes and dynamics that are omnipresent in science, technology, but also in our everyday lives.Upcoming project will therefore investigate theoretical foundations for visualization of processes. Physiological processes that describe the complex machinery of biological life will be picked as a target scenario. The reason for this choice is two-fold. Firstly, these processes are immensely complex, are carried-out on various spatial and temporal levels simultaneously, and can be sufficiently understood only if all scales are considered. Secondly, physiological processes have been modeled as a result of intensive research in biology, systems biology, and biochemistry and are available in a form of digital data. The goal will be to visually communicate how physiological processes participate on life by considering the limitations of human perceptual and cognitive capabilities. Solving individual
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Protecting the thymic epithelial cells and thymopoiesis during hematopoietic stem cell transplantation' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Allogeneic hematopoietic stem cell transplantation (alloHSCT) is a common, often last-resort treatment for haematological diseases, but it is plagued by long-term morbidity and high mortality. Direct alloHSCT-induced damage to the thymus and subsequent loss of thymopoiesis, ie the production of new T cells, is considered one of the main reasons for these complications. Our limited understanding of how the thymus is damaged during alloHSCT restricts the development of thymus-protecting protocols. The goal of ProtecTHY is to unravel the intrinsic protective mechanisms of the human thymus and assess how alloHSCT affects them, with the ultimate objective of devising measures to prevent thymic damage. We take advantage of an innovative whole organ culture system for the human thymus developed in my laboratory and our extensive pre-existing collection of human thymus tissue samples spanning a diverse age range. ProtecTHY specifically aims to 1) discover how the thymus protects itself from external insults over the course of the human lifetime, 2) reveal how alloHSCT disrupts the human thymus microanatomy and how that damage can be prevented with a cellular therapy, and 3) examine how thymic damage affects the circulating true naive T cells and if existing clinical treatments for alloHSCT complications can restore the loss of thymopoiesis. We will apply state-of-the-art spatial and single-cell multiomics to dissect these protective layers of the thymus both ex vivo and after alloreactive challenge in vitro. Moreover, by testing the effect of treatments already in clinical use, ProtecTHY can resolve their specific mechanisms of action and impact on the thymus. Our results are thus directly translatable to the human condition and can direct future treatments to enhance outcomes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Vitrification of metallic hydroxyde sludges'.

assistant: **Objectives**

The surface treatment industry produces a large volume of aqueous effluents highly polluant due to an important concentration in heavy metals. In most of the time, in order to clear off their waste water, the companies use coprecipitation processes which give a lot of hydroxide sludges. These sludges are very pollutant and are up to now directly stored in class I or 2 dumps, without any treatment, thereby causing severe pollution problems. So, current European environmental legislation on dump storage will be introduced to collect only stabilized wastes in class I dumps from 1999. Anticipating the legislation, this project aims at converting 100% hydroxide sludges into an inert solid waste meeting at least the European criteria of storage in dumps, and able to be valorised a l raw material in building and motorways construction for instance. In a first step, the sludges will be solubilized by means of selective solvants in order to extract heavy metals. Then the solution containing the pollutant elements will be concentrated and vitrified to confine the toxic wastes in inert glasses able to preserve environment from pollution (resistance to leaching) and thus allowing valorisation. The project aim at achieving an inert solid waste at effective cost, reducing the bulk of this solid waste (5 factor or more) and reducing the water consumption (whole or partial recycling).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Optical properties of MgB2-based superconductors' (EYA).

assistant: **Concept**

The discovery of superconductivity in MgB2 has initiated a frantic activity worldwide both theoretically and experimentally in order to understand its physical properties and their implications to the observed superconductivity, since the compound is very promising for practical applications. However, despite the great progress to understand the properties of MgB2, there are open questions that have to be addressed concerning the temperature and pressure response of the E2g phonon mode, which is responsible for the superconductivity in MgB2.On the other hand, these systems exhibit unique properties and atomic substitutions may influence the basic properties of MgB2 superconductor making it appropriate for potential applications. In analogy with the high Tc cuprates we will use an alternative approach for the understanding of the properties of MgB2 by following the evolution of properties of doped MgB2-systems under external perturbations like temperature or pressure. Therefore, we plan to extensively study b y means of Raman scattering at ambient conditions as well as under high pressure or low temperatures the vibrational and the super-conducting properties of various doped MgB2-based superconductors.These compounds are synthesized and characterized with various experimental techniques during my initial fellowship in Prof. K. Prassides research group (University of Sussex, UK). Also, we intent to synthesize novel mixed alkali/transition metal borides with stoichiometry, (A,TM)xMg1.xB2 where A=Li+, Na+ and TM=Z n2+, AI3+. By employing the Raman spectroscopic technique on selected doped MgB2 compounds as a function of both temperature and pressure a wealth of information can be provided about:(i) the elucidation of the role of the E2g mode in the super-conducting process
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Multi-modal biomedical imaging for research and clinical application' (2002-2006).

assistant: **Concept**

Integrated Early Stage Training is offered in the fast growing field of biomedical imaging for medical research and clinical applications. The integrated use of modern imaging modalities is extremely important for non-invasive studies focusing on elucidation of functional and metabolic processes with high spatial resolution in major diseases (eg, cancer or diabetes).The optimised use of those modern imaging techniques in a clinical environment leads to improved individual diagnosis and improved local treatment strategies, often by image-guided minimally invasive surgery or conformal radiation therapy. The quality of research and clinical use, but also industrial development of new innovative products for the world market are hampered by the tremendous lack of well educated medical physicists with sufficient knowledge in imaging systems and their applications in most European countries (EFOMP survey). Rapidly increasing medical and economical costs will result from insufficient diagnostics.The proposed concept provides excellent theoretical and practical training for early-stage researchers in all important imaging modalities with contributions from research institutions with focus on magnetic resonance imaging/spectroscopy, modern computed tomography combine d with positron emission tomography (2 Research Sections in the Clinic for Radiology), magnetoencephalography (MEG Center) and conformal radiation therapy (Department for Medical Physics). All institutions work closely together and are embedded in the large university hospital of the University of Tubingen allowing insight not only in basic methodical research, but in the organization and realization of patient studies as well.All institutions are well experienced in theoretical and practical training of local physi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'EuroMED Cooperation. Inland and Marine Water Challenges'.

assistant: **Innovation**

The project supports the organization of the Italian Presidency event ‘EuroMED cooperation. Inland and Marine Water Challenges’, strongly emphasizing Mediterranean cooperation on research and innovation. In the framework of the ENP and the UNEP/MAP Barcelona Convention and in line with H2020 work-programme, the event is designed as a two day conference embracing present political debate for the identification of urgent challenges to advance the frontier of science and to foster technological innovation to sustain economic growth and EuroMED cooperation. The event - to be held in Naples in September 2014 - offers the unique opportunity to underline the links between inland and marine waters, with special emphasis to the impacts that such a link has on society and economic growth, particularly in a Region whose relevant economic activities like fishery, agriculture, and coastal and marine tourism are clearly affected by the water management issue. As milestone towards the definition of a roadmap to tackle these objectives, on the first day four parallel workshops will address: (1) Water resources and land management impacts on inland and sea water in the Mediterranean Region; (2) A Mediterranean integrated Ocean observing system to support sustainable coastal and marine tourism; (3) Building Ecosystem based approach to Fishery and Aquaculture in the Mediterranean Sea; (4) Ecosystem-Based Management (EBM) in the Mediterranean Region. On the second day, a plenary session will finally deliver the key output message. In order to guarantee the effectivness of the event, different stakeholders from public and private sector will actively be involved in the organization, including policy makers at Ministry level and private companies. Besides Member States and international orga
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Prevention of Radiotherapy and Chemotherapy Induced Oromucosal Wounds Using an Oral Application Gel: Murnia® Mouth Gel' to be submitted under Horizon Europe.

assistant: **Abstract**

Cancer is a devastating and costly condition expected to increase significantly by 2030. According to the 2018 WHO report, the global cancer burden is estimated at 18.1 million new cases annually . Mucositis is a condition in cancer patients that manifests as severe ulcerations in the mouth and the gastrointestinal tract. Oral mucositis (OM) is cancer treatment's most significant side effect worldwide . Mucositis can be caused by chemotherapy and/or radiotherapy. It occurs in nearly 40% of patients receiving conventional CT, 80% receiving high-dose CT as conditioning for haematopoietic stem cell transplantation, and 100% receiving H&N radiation therapy, with 65% of those progressing to severe grade levels with significant adverse outcomes.The problem with OM is that while current therapies are focussed on dealing with its symptoms like inability to eat or significant pain, there is no real cure or prevention for OM itself. Existing products in the market for OM mainly offer symptom management focusing on pain or, at best, duration reduction claims. The one approved drug for chemotherapy and radiotherapy, Amifostine, has severe side effects and tumour protective properties, making it hard to use as it interferes with the actual cancer treatment. Kepivance, which is only approved for haematological malignancies, is challenging to administer, posing compliance issues and does not solve the more significant need for solid tumours.Umayana has developed a proprietary preventative and curative formulation to combat OM in cancer patients. Global Patent: WO2020072987 USA Patent: 11331360 (B2).


**Keywords:** Oral Mucositis,  Cancer, Head and neck cancer, Wounds
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Marine Renewable Integrated Application Platform', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

MARINA is a European project dedicated to bringing offshore renewable energy applications closer to the market by creating new infrastructures for both offshore wind and ocean energy converters. It addresses the need for creating a cost-efficient technology development basis to kick-start growth of the nascent European marine renewable energy (MRE) industry in the deep offshore – a major future global market. The project combines deep-water engineering experience from European oil & gas developments during the last 40 years, state-of-the-art concepts for offshore wind energy, and the most promising concepts in today’s R&D pipeline on wave energy and other marine renewables. The MARINA project is designed to capitalise on the vast body of proven marine technological knowledge gained in one of the world’s most hostile off-shore operating environments: the Northern European seas. MARINA will bolt this practical technology skill set onto the research base of the emerging – but still marginal – EU MRE industry and ensure its continued world-leading role. The MARINA project is therefore of major strategic significance for Europe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Implementation and integration of advanced Robotic systems and intelligent Environments in real scenarios for the ageing population' (Robot-Era) under Seventh Framework.

assistant: **Objectives**

The objective of the Robot-Era proposal is to develop, implement and demonstrate the general feasibility, scientific/technical effectiveness and social/legal plausibility and acceptability by end-users of a plurality of complete advanced robotic services, integrated in intelligent environments, which will actively work in real conditions and cooperate with real people and between them to favour independent living, improve the quality of life and the efficiency of care for elderly people.The Robot-Era proposal is conceived as an IP project because of its ambition to design, implement and validate a set of robotic services for ageing well", facing fundamental scientific and technological challenges on robotics and ambient intelligence, cognitive-inspired robot learning architectures, elderly user-needs, design for acceptability and legal/insurance regulations and standards for real deployment.The ambition of Robot-Era project is to significantly enhance the performance and acceptability of the current services to a new level of quality. Different already available and commercial robotic systems will be adapted and integrated to cooperate and operate in domestic, condominium and outdoor environments. The level of robotic services will be effectively enhanced thanks to the inclusion of cooperative robots that will be able to  contemporarily act in indoor and outdoor environments, and of the AmI infrastructure, fully integrated in domestic and urban contexts that will facilitate the operations of robots, provide effective tools to supervise the various scenarios and ensure safe operations, and connect end-users, service providers and robots. The Robot-Era proposal aims to implement a fully realistic and real experimental setup in urban and domestic environments and with diff