RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Cell-based regenerative medicine: new challenges for EU legislation and governance' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

This proposal aims at collecting and analysing facts and figures in order to assess the current legislation on the therapeutic use of somatic cells, and to bridge it with the research infrastructure capacity building. Although EU has adopted 3 Directives on Tissues and cells between 2004 and 2006 to harmonise the procurement, storage and use of cells for therapeutic use in Europe, countries have implemented these directives in very different ways. Furthermore, research has been partially covered by the initial regulation, calling into question the match between regulation and practices that will develop in the near future, in particular with the emergence of European research infrastructures. Finally many changes have occurred in the scientific, legal and institutional environment of cell use, leading to a necessary update of this regulation with regards to its implementation in national legislation and its impact on research practice and innovation. Two domains are at stake: research (infrastructures) and medical practice/public health measures (cells). The therapeutic use of cells is regulated by EU law whereas its research counterpart is mainly depending on national laws and regulations. This gap calls for a coordinated action in order to optimize the translational process, since the full pipeline is not coherently taken into account in current legislations. To achieve these objectives, our project relies on a coherent consortium of experts in the fields of cells therapies, cells banks and translational biomedicine, having strong expertise in law and/ or in governance issues. After 36 months the project will deliver evidence about the contemporary practices around cells and will design a picture of the “market” and its distribution between the public and private sect
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Crystallographic analysis of lmra, the bacterial homologue of the human multidrug resistence p-glycoprotein' (1998-2002), addressing dissemination and exploitation.

assistant: **Impact**

LmrA from Lactococcus lactis is integral membrane ABC transporter, responsible for the extrusion of a variety of drugs from the inner leaflet of the cell. Our aim is to determine the crystal structure of LmrA in complex with non-hydrolyzable nucleotides and allosteric modulators. This structure would be the first for a complete ARC multidrug transporter. To perform a structural analysis through X -ray crystallography various subsequent steps must be satisfied: protein over expression and purification in quantities, protein crystallization, phase problem analysis and resolution, model building and refinement. I will take part to all these aspects of the experimental work and will be trained in the methodology and treatment of membrane proteins. This will be of great impact to me, given the scientific value of the project, but also the amount and quality of experimental work that I will have to perform. The impact to the host institution may be also quantified basing on the importance of the project from a scientific and bio-medical point of view. Membrane proteins have been and will continue to be the highest challenging objects of research in Structural Biology and the host laboratory will contribute to the advances in the field.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Battery management by multi-domain digital twins' under Horizon Europe.

assistant: **Concept**

Physics and data-based battery management by multi-domain digital twins (BATMAX) sets out to pave the way for advanced next generation data-based and adaptable battery management systems capable of fulfilling the needs and requirements of various mobile and stationary applications and use cases. The main objective of the project is to contribute to improving battery system performance, safety, reliability, service life, lifetime cost and therefore to maximise the value created by operation of the battery systems in various kinds of end use applications. This is approached by creating a framework for next generation of battery management based on large amounts of data, both experimental, operational and synthetic, adaptable physics-based models, suitable reduced-order models for both physical BMS algorithms and real-time multi-scale digital twins. BATMAX develops a framework to efficiently parameterise physics-based models is essential to reduce the cost of model development and encourage their use in BMSs. Advanced numerical methods accelerate the extraction of relevant parameters from experimental and numerical simulation data. BATMAX develops hardware and sensorisation on cell and system level for collection and communication of battery measurement data and integrates an open source BMS platform to a laboratory scale prototype system. The BATMAX BMS framework (hardware and software) will enable to exploit advanced battery models with integrated digital twin framework that is capable to cope with high amount of measured data, which will enable to monitor the battery aging in depth and to facilitate the key functions of systems. A central output is an extensive multi-purpose and scalable digital twin framework is developed and validated for advanced battery management.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'robusT Risk basEd Screening and alert System for PASSengers and luggage' (TRESSPASS).

assistant: **Innovation**

With regards to modalities, TRESSPASS project includes air, maritime and land (including car and train) border crossing points, and specifically also travel routes that combine different modalities. It excludes border crossings outside of border crossing points, such as happens with boats of refugees on the Mediterranean. With regards to threats, this includes smuggling, irregular immigration, cross border crime, and terrorism, including threats to the transport itself (so, including e.g. aviation security – per the topic text). It excludes other threats such as posed by state-actors. This proposal includes all tiers of the four-tier access model: (1) measures undertaken in, or jointly with third countries or service providers; (2) cooperation with neighbouring countries; (3) border control and counter-smuggling measures, and (4) control measures within the area of free movement.TRESSPASS will (1)develop a single cohesive risk-based border management concept (2)develop three pivoting pilot demonstrators (3)demonstrate the validity of the single cohesive risk-based border management concept by using red teaming and simulations(4)prepare for the further development of this concept beyond this project by linking to other known risk-based border management projects (in- and outside EU, within EU research frameworks and on national levels), and describe how their results contribute to a single cohesive risk-based border management concept


**Keywords:** Risk based screening
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Behavioural Economics in Network Games' (BEING), addressing dissemination and exploitation.

assistant: **Impact**

Three aspects of social interaction shall be combined, namely the diffusion of information in a social network, the formation of social networks, and behavioural (i.e. irrational) aspects in decision making. These three areas are crucially interdependent: 1) unwelcome information and irrational behaviour may lead to a change in a person’s circle of friends and thereby to a change in the social network;2) the network itself and the (potentially irrational) processing of information influences the information diffusion in a society;3) the decisions that have to be made with respect to network formation can be influenced by the disutility of unwelcome information rather than the utility of being correctly informed and thereby lead to irrational behaviour.This shall allow for an integrated approach in the analysis of social dynamics.While the three parts of this project already form an ambitious project that will provide considerable academic impact, they will also lead to interesting follow ups and spin-off research that is highly relevant in the upcoming years, such as the analysis of information diffusion in social networks prior to the European Election in 2019, and to applications outside academia, such as optimising product placement and advertisement in social networks, or the development of measures that prevent vigilantism in social networks.The combination of network formation, innovation diffusion, and behavioural economics is not only a novel approach to these rather young research areas with potential impact in economics, psychology, social sciences, and even computer sciences; it is also a highly relevant topic for modern societies where social media play a crucial role in daily communication and information aggregation. This project will therefore not only ad
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Following the paths of itinerant professionals of the arts in the epigraphic sources of the Hellenistic period' (2014-2020).

assistant: **Concept**

Various reasons can inspire a travel. Travelling for art implies embracing new challenges, being prone to staying in the limelight and to taking risks, chasing glory, rewards, and money. Throughout the Hellenistic period and beyond, itinerant professionals of literacy and music travelled around Greece for all the above. The endeavours, paths, stories of the “poeti vaganti” -so called after the preliminary study by Guarducci (MAL 1927-1929)- are mainly documented by epigraphy, allowing us to envision a cultural and popular phenomenon that run parallel to court literature. Unknown artists and accomplished intellectuals showed off on all the renowned stages of the Hellenistic centres, delivering their performances at festivals, sacred celebrations, and occasions that gathered audience from the territory and abroad. Although the compositions of itinerant artists are sporadically preserved being mainly intended for oral use, epigraphy provides us a large spectrum of valuable elements leading through the reconstruction of the Hellenistic performative life. The study of inscriptions shows three main osmotic levels allowing us to interpret correctly the data and reach out the essence of the “movement” of itinerant professionals of the arts. The central point of this scenario is Travel, as the title of this project indicates: the expression from a Tanagra epigram (IG VII 530) “ptanois posin”, i.e. with winged feet, enshrines the essence of itinerant arts. Travel leads to disclose Performance, studied by typology and nature, and Travellers, traced in their stories and careers. This project, which obtained the Seal of Excellence in MSCA-IF-GF-2016 and also benefits from a digital version (to be developed with the CHS Harvard University partnership), investigates the “poeti vaganti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Functional implications of the remarkable conservation of eukaryotic gene architecture' (FUNCTIONARCHITECTURE).

assistant: **Innovation**

One of the fundamental principles in comparative genomics is that evolutionary conservation implies functional importance. This principle has been used extensively in the life sciences, as a tool to detect biological functionality. In the vast majority of studies, evolutionary conservation has been sought in three biological “entities”: sequence (actual nucleotide or amino-acid sequences, as well as sequence properties like codon usage bias, GC content, and amino-acid bias); structure (like RNA, DNA and protein secondary and tertiary structures); and genome architecture (like synteny, gene order, relative gene orientation). These strategies have worked very well, but evidence is rapidly accumulating that there is a lot of “function without detectable conservation”. Many factors can potentially contribute to such “undetected functionality”, such as functions that do not depend on sequence or structure (for instance, nonsense mediated decay is affected by the mere location of the introns), functions that depend on very short and redundant sequence motifs, co-evolution of factor and target, and migration of functional sequences along the chromosome. We suggest a novel strategy to identify parts of these “undetected functions”. We study how to quantify the conservation in a fourth type of biological “entity”, that we dub gene architecture, and which is derived from the exon-intron structure of the gene. To this end, we are building a eukaryotic gene architecture database, and developing an algorithm to quantitatively evaluate the level of architectonic conservation in the different regions of the gene. Preliminary analysis reveals that conservation of gene architecture is plentiful, and in many cases it can be detected over very long evolutionary times (more than a billion
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Area yield improvement in the fabrication of leather, enhancing leather characteristics and diminishing environmental impact'.

assistant: **Innovation**

In the laether manufacturing the raw material is purchased by weight, whereas the finished product is sold by area; any improvement in the area yield have a considerable commercial importance. The processes in which leather manufacture is involved reduce the area obtained in the product. The methods used to improve the leather area deteriorites its mechanicals characteristics, and yield improvement is lost in the finishing operations or in storage of leather.A thermal treatment made on flat stretched leather immersed in a water saturated medium, before the drying step, will allow:1. To develop a process able to improve the area in leather;2. To improve the fixation of tanning, dyeing and fatliquoring substance, enhancing the overall leather fastness characteristic as well as it thermal resistance, reducing the environmental impact and health risk of leather articles end users;3. To reduce the sensibility of leather to moisture variation that affect negatively the comfort and aesthetic appearance of leather products;4. To accommodate the technology to an feasible industrial process, without deteriorating the characteristics of the tanned hides.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Environmental Turn of Dance: Convergence of Therapeutic Practice, Art Creation with AI and Community Practice' (ETD).

assistant: **Innovation**

“Environmental Turn of Dance: Convergence of Therapeutic Practice, Art Creation with AI and Community Practice” (ETD) is a groundbreaking research endeavor poised at the nexus of dance studies, environmental philosophy, and AI technology. The project seeks to investigate how dance can effectively generate awareness of, and proactive responses to, the challenges posed by climate change. Specifically, the research will evaluate existing initiatives, performances, and collaborations that integrate dance and climate change and identify the ways in which dance can contribute to climate change education, advocacy, and the promotion of sustainable practices in Malta. With urgency stemming from contemporary ecological challenges, ETD aims to redefine the role of dance as a catalyst for ecological consciousness, addressing the why of our environmental crisis in a novel, embodied manner. The current moment demands immediate action in reshaping our relationship with the environment. ETD acknowledges the pressing need to infuse environmental awareness into artistic expression. This urgency aligns with global concerns for climate change and ecological well-being, propelling us to address environmental issues creatively, fostering a sustainable future.Methodologically, this project seeks to unravel the intricate interplay between dance and the natural environment, shedding light on unexplored dimensions. Moreover, ETD pioneers the integration of AI technology into dance research, emphasizing innovation and collaboration. This approach marries creative artistry with cutting-edge tools, enabling dynamic exploration of ecological themes. ETD exemplifies my profound interdisciplinary expertise. My recent international projects have skillfully developed intersectional knowledge, bridging
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Archaeological and Anthropological Unravelling of Chickens using Ancient DNA in Neotropical America' under Horizon 2020.

assistant: **Concept**

With three chickens for every human being at any given time, poultry production is a key agricultural player, providing an efficient source of protein to billions of people regardless of religion or culture. Neotropical America contributes over a fifth to global poultry production, yet chickens only arrived on the continent 500 years ago. Since, they have played a central societal and economic role in local communities and are now well embedded within the continent’s numerous cultures. Though details surrounding their European and Polynesian introductions and spread throughout Neotropical America remain unclear, these birds have adapted to the continent’s diverse environments including diseases, leading them to display a unique genetic pool of phenotypic, productivity, adaptation and disease-resilient traits. Yet with an increasing consumer demand, local populations are being crossbred with commercial stock, and a lack of identification, characterisation and conservation of the indigenous gene pool is leading to the erosion and loss of that unique genetic make-up. Combining archaeology, anthropology, history and ancient population genomics, ARAUCANA aims to document the cultural history of chickens in Neotropical America (such as Argentina, Brazil, Chile, Peru, Uruguay and the Caribbean), as well as begin mapping the evolution of indigenous traits linked to environmental adaptation, disease resistance and productivity by characterising the past genetic diversity of local chicken populations through time. It will also attempt to recover ancient (partial) pathogen genomes in order to trace their evolution and spread through time in relation to specific lifeways and environments. This will enrich our understanding of the biomolecular mechanisms and pathogenesis of infectio