RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Personalized disease prediction and prevention in chronic inflammatory disorders' under Horizon Europe.

assistant: **Concept**

Background: Chronic inflammatory diseases (CID) are a group of non-communicable disorders of the immune system with a lifetime prevalence of over 10% in the EU. Rheumatoid arthritis (RA) and inflammatory bowel diseases (IBD) are two archetypal CIDs with a particularly high unmet medical need and impact on European health care systems. Objectives: The PerPrev-CID consortium aims to set up new standards for decision support tool development for preventive and early therapeutic interventions in RA and IBD. Selected main aims are: (i) To define actionable predictors from longitudinal multi-level Omics and clinical data integration In RA and IBD. We will identify markers indicating progression from pre-symptomatic to manifest disease and signatures predicting early disease relapse (ii) To develop new tools for home-based and continuous assessment of patient-related data dimensions using digital health apps/wearables, including more innovative, objective parameters, such as movement patterns, physical activity, and sleep. (iii) To assess the health-promoting effects of interfering with the tryptophan pathway in a proof-of-concept nutritional study in early RA and IBD. (iv) To study ethical, legal and economic consequences of risk assessment and early low-threshold preventive interventions. Important aspects are the communication of the risk concept, economic implications of broad testing and interventions as well as patients´ perception of the concept of risk prediction. Expected impact: We will develop prototype solutions for privacy-preserving AI-based data analysis for research and clinical application and will test a first proof-of-concept low threshold intervention in RA and IBD. Our approaches will provide a clear health benefit to the citizens of the EU by improving he
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Catholyte-free flow cell enables high efficiency electroreduction of CO2 to C2 fuels'.

assistant: **Objectives**

In the light of rising levels of atmospheric CO2 and associated climate change, the development of advanced techniques for CO2 conversion is of foremost importance. Particularly, many efforts have been made recently to synthesize efficient electrocatalysts for CO2 reduction to carbon fuels using renewable electricity. Nevertheless, to meet the requirement of industrial implementation, even the best performance of these recently developed electrocatalysts must be increased by one order of magnitude. Currently, energy efficiency of CO2 electroreduction is limited by energy-loss in catholyte and transport of CO2 to the cathode surface. The importance of transport limitations will grow as currents approach the higher levels required for industry. The vision for this work is the design of an efficient catholyte-free electrode structure and reactor, in combination with state-of-the-art photovoltaic, that can provide for the industry-ready artificial photosynthesis of carbon fuels. To achieve this goal, we will be dedicated to develop a membrane electrode assembly cell with the design of a catholyte-free flow-through-porous electrode which will allow the incorporation of newly types of nanostructured electrocatalysts and efficient CO2 transfer and conversion into specific carbon fuels such as ethylene or ethanol. Particularly, the proposed research aims include: (i) Development of efficient electrocatalysts that allow the formation of ideal products (ethylene/ethanol); (ii) Enhancement of electrocatalytic activity and stability via system engineering; (iii) Understanding the fundamentals of CO2 electroreduction and cell mechanics to accelerate the development of catholyte-free flow-through-porous electrode for the design of a scalable, high-performance CO2 electroconversion ce
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Ionization dynamics - coincidence studies of electron and positron impact' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Research objectives and content To study the role of polarization, correlation and exchange effects in electron impact ionization of neutral targets. To study the role of non-local potentials, exchange and poistronium formation, on electron and positron impact ionization of atomic hydrogen. To consider spin asymmetry measurements on Li and Xe and determine the influence of exchange and relativistic effects. To explore the possibility of using Density Functional Theory to treat exchange- correlation effects in electron and positron impact ionization. Developing a Distorted Wave Born approximation where exchange is treated exactly in the incident and final channels Exploiting Density Functional Theory to create local exchange-correlation potentials. Implementing the computer codes on the latest generation of parallel processors. Training content (objective, benefit and expected impact) Advanced Training will be given in research in Atomic Collision theory Density Functional Theory and the use of the latest computer technology. I hope to be able to interact with the aim (e,2e) experimental groups in Europe who will benefit from my work. Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Detecting Document frauD and iDentity on the fly'.

assistant: **Concept**

The D4FLY project will augment the current capabilities and capacities of border authorities in countering emerging threats in document and identity verification (e.g., forged documents, impostor fraud, morphed faces) at manual and highly automated border control points and in the issuance process of genuine documents. The confluence of D4FLY set of tools and systems will improve the quality of verification and reduce major time sinks in the processes thus enabling real on-the-move border crossing experience for travelers. Novel sensor hardware based on advanced lightfield cameras and novel algorithms developed in the project will enhance verification accuracy and robustness via the combined usage of 2D+thermal face, 3D face, iris and somatotype biometrics. Analytical means to identify known criminals based on somatotype and 3D face data generated from mugshots and observation data will be developed. Various operational needs of end-users with different threat landscapes constitute the backbone of D4FLY development efforts. D4FLY will create a resilient document verification system that can verify a multitude of physical and electronic security features (e.g. Kinegrams®, MLIs, CLIs), detect complex forms of electronic fraud and advanced morphing, and identify fraud in breeder documents. The potential benefit of blockchain technology in identity verification will also be investigated. The D4FLY solution will consist of a border control kiosk geared with enhanced enrolment, verification and detection capabilities; smartphones applications for improved performance and verification capabilities; and a non-stop on-the-move system for biometric verification. The innovation will be validated against European societal values, fundamental rights, privacy, data protection and app
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Mechanism of vertebrate sperm-egg recognition and fusion'.

assistant: **Concept**

The life of every sexually reproducing being can be traced back to a singular event: the fusion of sperm and egg. Gamete fusion is perhaps the most critical step in the process of fertilization. However, the mechanisms underlying vertebrate sperm-egg fusion and the events that precede it (sperm-egg recognition) are largely unknown. Uncovering the molecular machinery and biophysical mechanisms mediating sperm-egg recognition and membrane fusion in vertebrates is therefore one of the biggest challenges in fertilization research. In this project we aim to uncover the mechanistic principles of vertebrate fertilization by exploiting the unique advantages of zebrafish as a vertebrate model in combination with in vitro reconstitution assays. We will focus on two main questions:1)What is the molecular mechanism of sperm-egg recognition?2)What are the molecular and biophysical principles underlying sperm-egg fusion?To identify new essential components of the sperm-egg recognition and fusion machineries, we will develop candidate and unbiased screening approaches. We will combine functional studies in vivo, using phenotypic, genetic, biochemical, and advanced high-resolution imaging approaches, with mechanistic studies in vitro, using structural and reconstitution assays, to rigorously determine requirement and sufficiency, causal relationships, spatiotemporal dynamics and mechanisms. Our recently discovered fertility factors Bouncer (sperm-egg recognition) and Dcst1/2 (sperm-egg fusion) provide precise entry points for screens and for functional and mechanistic studies.Overall, our goal is to mechanistically understand how sperm and egg recognize and bind to each other, and how their membranes subsequently fuse. The insights gained will form the basis for our ultimate vision, to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The male-female health-mortality paradox' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

From the 1960s to the 1980s a common wisdom about differences between males and females in health and mortality emerged which was summarised by the well-known phrase ""women are sicker, but men die quicker"". Recently this wisdom has been increasingly questioned. Nevertheless, the general idea of a paradoxical relationship between health and mortality among women and men persists until today. The purpose of this project is to decisively advance the understanding of the paradox by demonstrating that the reverse relationship between sex on the one side and health and mortality on the other is not as paradoxical as it seems. We hypothesise that two factors are mainly responsible for causing this intuitive contradiction. First, the overall reversal in sex morbidity and sex mortality differentials occurs because conditions that figure importantly in morbidity are not very important in mortality, and vice versa. Second, it is very likely that longevity is directly related to the absolute number of life years in ill health. Thus, women show higher morbidity rates not because they are female but because they are the sex with higher life expectancy. We will test these hypotheses in a ""natural experiment"" by analysing the relationship between health and mortality among Catholic nuns and monks from Austria and Germany in comparison to women and men of the general population. Cloister studies have a long scientific tradition and provided path-breaking knowledge for human medicine and demography, including the applicant s research during the last decade. This project follows the line of this tradition and will investigate the male-female health-mortality paradox in a longitudinal setting that is as close as one can get to an ideal long-term experiment in humans.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Greater RAIL Safety using the Smart Washer Ecosystem' (GRAILS-SWE), addressing dissemination and exploitation.

assistant: **Impact**

9% of all EU freight (280 billion tonne-kilos) & 381 billion passenger km were travelled on EU rail networks in 2014. A railroad switch & crossing (point) is a mechanical installation enabling trains to be guided from one track to another. Point integrity is vital; there are on average 31 critical fastenings at each switch. Across the EU, SCF was responsible for 21 derailments between 2005-2010. Globally, SCF is responsible for 5.77% of all derailments (6th largest cause of derailments). SCF is a leading cause of signalling failure, leading to delays; 9.5 million minutes of passenger delays due to SCF occurred during the 2015/2016 audit period on the UK rail network alone.   EU rail infrastructure owners are implementing ‘intelligent infrastructure’ solutions across their rail networks that enable remote condition monitoring (RCM) & condition based maintenance (CBM) as a way of monitoring assets, such as points, to increase reliability & capacity of rail networks. To enable RCM & CBM, Smart Component Technologies (SCT) have developed their proprietary ‘Smart Washer’ platform technology. Smart Washer 3 (SW3) is a washer containing a multitude of sensors that is deployed at critical fastenings at points to measure parameters (including clamp force & movement) from directly within the fastening. Through a connected Data Controller Unit (DCU), the measurements are fed in real-time to a cloud based server that interfaces with RCM software used by those responsible for the maintenance of rail tracks to remotely monitor the entire switch asset, as well as track bed stability (including voids & track geometry/inclination).Combined, the SW3 & DCU comprise the ‘Smart Washer Ecosystem', which offers a full ‘end-to-end’ solution for RCM & CBM; this will service the Rail infrastruct
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Health and Wellness on the Beat' under Seventh Framework.

assistant: **Concept**

There is a tight link between the rhythm of external information (e.g., auditory) and movement. It can be seen when we spontaneously or deliberately move on the beat of music (e.g., in dance), or when we enjoy performing physical and sport activities (e.g., running or cycling) together with music. This propensity to match movement to rhythm is natural, develops very precociously, and is likely hard-wired in humans, as shown by cognitive sciences and neurosciences. In this proposal, we exploit this compelling link between music and movement for boosting individual performance and enhancing health and wellness. This goal will be achieved by creating an intelligent technological architecture - BeatHealth. Our architecture will deliver embodied, flexible, and efficient rhythmical stimulation adapted to the individual's skills with the goal of enhancing or recovering features of movement performance (i.e., kinematics and physiological performance). This endeavour is highly multidisciplinary. It involves (i) fundamental research aimed at improving information parameters, for maximizing the beneficial effects of rhythmic stimulation on movement kinematics and physiology, (ii) technological development to achieve state-of-the-art system reliability, flexibility, and portability of the BeatHealth architecture, and (iii) the creation of a new IT service in the form of a network-based application for collecting on the fly kinematic data and sharing them with online with others (e.g., medical doctors, family, coach, etc). The beneficial effects of BeatHealth will be evaluated in patients with movement disorders (i.e., Parkinson's disease), and in healthy citizens of various ages with moderate physical activity.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'IBEX QDR: A Ground-breaking Technological Upgrade based on Quantitative Digital Radiography to Exploit the Full Diagnostic Potential of Standard Digital X-Ray' in the context of a Horizon 2020 call.

assistant: **Objectives**

Bone density loss is a natural process that affects us all as we age. As the loss advances, so does the risk of fracture. The lack of warning symptoms or routine tests results in a late detection of severe density loss (osteoporosis), often when the first fracture occurs. Besides being a major social burden, in the EU it entails costs of €37 bn/year in treatment, disability or productivity loss, which could be alleviated if population-wide bone health screening methods were available. Today, measurement of bone mineral density (BMD) is only available through scarce and expensive DEXA scans, limiting testing to referred individuals grouped as high risk of osteoporosis. In response, we at IBEX Innovations have developed and patented IBEX-Quantitative Digital Radiography (IBEX-QDR). Conceived as a cost-efficient upgrade for standard digital radiography systems, it enhances the quality of digital X-ray images and enables these systems to measure BMD. All while reducing by 2-fold the X-ray dose needed to obtain the image. Altogether, IBEX QDR will unleash the diagnostic potential of digital radiology, enabling routine screening of bone density with any standard X-ray examination. In a Phase 1 project we confirmed the market opportunities for IBEX-QDR, outlined technical optimisations and achieved high-level engagement with X-ray detector and system manufacturers and healthcare providers. Now in Phase 2 we aim to reach market readiness by finalising the technological development, completing its clinical validation and securing the business aspects of the project. Once in the market, IBEX QDR will bring significant benefits for healthcare systems (early diagnosis and lower impact of ageing diseases), professionals (safer and simplified work-flows) and public health (lower radi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'A predective design method for machining advanced ceramics' in the context of a Fourth Framework call.

assistant: **Objectives**

The research will be carried out with the aim of realising an advancedmachining technique for glass and tough structural ceramics capable of reducingthe machining time with 10% and better controlling of the surface roughness. Toutilize the machined parts in several products a cheaper metal-joiningtechnique is developed. There is a growing demand for structural ceramics andglass in Europe and the rest of the world. They are used in valves, turbines,opto-electronical devices and in equipment for the semiconductor technology. Uptill now, machining is responsible for 80% of the cost of high precisionstructural ceramic products. The structural ceramics market is growing in Japanand USA mainly due to the lowering of the machining cost of ceramics. TheEuropean growth of advanced ceramic market lacks behind because of the poorunderstanding of machining parameters. Improving this technique would give >European competitive advantage to fill an already developing industrial demand.Research will be carried out by a multi disciplinary team concentrating onimproved machining conditions, lubricants and diamond tools, and on producing apredictive design method for machining ceramic preforms and tough advancedceramics, as function of their composition. The potential reduction of cost of machining advanced ceramics (European market) is 40 MECU/year.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Implementation of the measuring instruments directives (mid) with regards to software of measuring instruments (mid-software)', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

The Network aims at harmonising MID implementations with respect to software of measuring instruments. It includes the development of category-specific software requirements, the recommendation of test methods, the establishment of compliance with relevant international standards of IT security and software quality, and the identification of future needs with regard to upcoming information technologies. The Network is motivated by software requirements so far not uniquely interpreted. Requirements and test procedures shall be harmonised in order to achieve a technical interface agreed between manufacturer and Notified Bodies and thus to form the basis for comparable assessments in various European member states. The main deliverables are guidance materials for both, manufacturers and Notified Bodies. Great importance is given to information distribution and training activities at regional level.