RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'X-chromosome biology and immune health in females' in the context of a Horizon Europe call.

assistant: **Objectives**

Females have a higher risk for autoimmune disease and lower risk of mortality from infectious disease than males, reflecting a more robust immune response in females against both self-antigens (autoimmunity) and non-self-antigens (infections). Genes that escape the process of X-inactivation (XCI) are present in a higher dose in female cells and many play key roles in T-cell biology. XX-Health will reveal the role of escape genes in mediating sex-differences in T-cell response.  Different cells in a tissue can inactivate the maternal (Xm) or paternal X-chromosome (Xp) (mosaicism). In addition, different ratios of Xm and Xp may become silenced in cells of a given tissue resulting in skewed X-inactivation (sXCI), rendering functional dissection of XCI very challenging. Rare females (~1:300) inactivate the same parental X-chromosome in all cells (cXCI), removing the confounding effect of mosaicism, and offering a powerful genetic system in which to dissect XCI in T-cell biology. We will develop a novel methodology, TriX-Seq, allowing high-resolution screening of sXCI and cXCI in a large (N~8,000) unselected cohort of females. Using T-cells isolated from identified cXCI females, we will (i) generate a unique multi-omic map of XCI during human T-cell differentiation at a resolution well beyond the state-of-the-art and (ii), directly test the function of alleles specifically expressed from the inactive X-chromosome (Xi) in T-cell biology. With sXCI data in hand, we will also reveal the associations, if any, of sXCI with disease risk and use the unique availability of parental and grand-parental DNA to assess the genetic origin of cXCI.  Sex-bias in COVID-19 mortality has highlighted the importance of sex as a contributor to disease risk. The technical and conceptual advances d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Spatial super-resolution of electrophysiological measurements' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Electroencephalography (EEG) is the non-invasive recording of electrical brain activity, and is an indispensable diagnostic and research tool. A significant advantage of EEG compared to other brain imaging modalities is its high temporal resolution. The downside of EEG is, however, its poor spatial resolution, which is one of the reasons for its gradual replacement by costlier alternatives. It results mainly from the sharp discontinuity in the electric conductivity of the skull bones acting as a strong low-pass filter and limiting the amount meaningful information that can be extracted from EEG signals. We propose a novel concept of EEG measurement hardware which, in combination with signal processing techniques, will increase the spatial resolution of EEG by as much as an order of magnitude. Our idea is based on the observation that by connecting a dynamic network of controllable impedances between pairs of measurement electrodes, one can alter the shape of the spatial filter constituted by the skull. Since EEG is a relatively narrow-band signal (about 100Hz, limited by the time constants of basics units of neural activity), we expect to be able to measure tens or hundreds of different configurations of the network, either directly or by using a compressed sampling scheme, without compromising the temporal resolution. This will introduce many independent equations to the EEG inverse problem and improve source estimation, having critical impact on the diagnostic capabilities of EEG as well as on its use in emerging applications such as neuro-feedback and brain-computer interface (BCI).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'INtegrating Social Evolution and Metabolic Ecology' (INSEAME), addressing dissemination and exploitation.

assistant: **Impact**

Over 3.5 billion years, life has evolved towards ever-greater size and complexity. At critical transitions, this occurred when entities formed collectives (e.g. cells into multicellular bodies, individuals into eusocial societies, species into obligate mutualisms). Towards explaining this trend, I will integrate two emerging perspectives—social evolution and metabolic ecology—using scaling laws to explore energy efficiencies gained as organisms crossed these major transitions. Extending my research on the physiology of fungus-growing ant societies, I will use a metabolic currency to study the evolutionary trend towards ever-larger agricultural systems. Ants (tribe Attini) began cultivating fungi 50 million ago and have since evolved into over 230 species common across the new world tropics. My research has suggested that these farming ant societies, like those of humans, face efficiency constraints related to metabolism. I found that species with larger colony-farms tend to become increasingly efficient, producing larger fungus crops while losing relatively less energy to metabolic respiration. I will extend advanced techniques I pioneered, using a cutting edge respirometry system to link performance and operational size at each level of organization, from newly-mated queens that found colonies, to societies of sterile workers cultivating fungus, and then whole colony-farms that use public health strategies to protect fungal symbionts. Decades of research by my host, Prof. Boomsma, have made fungus-growing ants a model system in biology, rivaling the honeybee, and I will use this system to ask fundamental integrative questions in biology. I will also transfer knowledge by organizing and teaching three courses—a respirometry course (2014) and a tropical field course in P
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Ultrasonic Inspection Solution for railway crossing points.' under Horizon 2020.

assistant: **Concept**

SAFT Inspect is an ultrasonic inspection solution for railway crossing points. Our technology facilitates for the first time full volume inspection of railway crossings. Rail crossing, known as “frogs” are mechanical installations that enable a train to switch from one track to another.  Frogs are subjected to repetitive impact from the rolling stock, causing fatigue cracking. For this reason, frogs are manufactured from manganese steel with work-hardening properties to be highly resistance to fatigue cracking. Unfortunately, this hardening property makes frogs extremely challenging to inspect. The huge problem is, once frogs are broken, causes train derailment.Current inspection techniques are limited to visual inspection, only inspecting frog surface, which is extremely risky. If a crack has not yet propagated trough the surface, will go undetected. However, when a crack has reached the surface, it needs to be immediately replaced.  Unscheduled maintenance of frogs can lead to multiple train delays blocking the entire railway for more than 6 hours causing heavy losses of €288,000 in penalties per day. Full volumetric inspection is essential as can be used to detect a crack before it has reached the surface to plan maintenance in advance. Ultrasonic inspection raises a candidate solution for full volume inspection due to ultrasound penetration. This technique is well established for rail track inspection, however when applied to frogs becomes ineffective. Manganese grain structure is very course. This makes the material highly attenuative to ultrasound resulting in poor penetration depth and low signal to noise ratio (SNR). We have overcome these technical barriers by applying an ultrasonic Inspection technique called Synthetic Aperture Focusing Technique (SAFT) combin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'An effective and environmentally friendly solution to control fire blight disease caused by Erwinia amylovora in pome fruit crops' under Horizon 2020.

assistant: **Concept**

The PhageFire project is devised to satisfy the unmet need for a secure and reliable solution to control fire blight (FB) disease in pome fruits caused by the bacterium Erwinia amylovora (Ea). The Spanish pome fruit producer, Peras de Rincón de Soto has partnered with Enviroinvest (Hungary) consultancy company expert in production, authorization and commercialization of phage-based pesticides, ZHAW (Switzerland) – a top research centre in phage therapy and Kimitec Group specialist in the design, development and commercialization of natural solutions for the plant protection sector. Together, PhageFire Consortium members aim to further develop an integrated phage-based solution enabling pome fruit farmers to effectively control Ea infections, reducing both production and economic losses. In addition, this will also result on reduced reliance on harmful chemicals (mainly copper-based products) and antibiotics. Based on our advanced current development of phages cocktails and their successful results on the safety and benefits of phages, our goal is to develop and commercialise PhageFire as the first-in-class phage-based biopesticide in Europe providing effective prevention and treatment against Ea infections. In order to take the project forward and reach product commercialization, a next estimated investment of €3.9 M is needed. The successful consecution of the FTI funding will help to cover the 70% (€2.97 M) while the Consortium partners will assume the 30% (€0.93 M) with own funds and the potential economic help from private investors. Considering the increasing demand for FB protection methods, PhageFire biopesticide will represent a great business opportunity (€22.12 M net profit between 2023-2027, ROI 4.66) by filling a highly profitable niche in the growing biopes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Spirits of Displacement and Diaspora', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Spirit possession cults puzzle Western observers, particularly when they appear in supposedly secular urban environments. Muslim migrants from North Africa, seeking to establish new lives in Southern Europe, have to negotiate the continuity of such ritual practices with the constraints and expectations imposed on them by their new social contexts. But the legitimacy of these cults is contested also in their homeland, where they face increasing pressures by religious fundamentalism. Space and its organization, especially in urban settings, play an important part in these disputes. In Morocco, spirits are thought to reside in particular places, such as tombs, sanctuaries, or street corners. How do possession cults continue to be practiced when spirits’ spaces of residence have to be abandoned or undergo demolition? This research compares the continuities and ruptures in cult performances as the spaces that host them are affected by both forced displacement and voluntary diasporic migration. I will observe the resettlement of a slum in Casablanca, and compare it with two Southern European neighborhoods where Moroccan practitioners of spirit cults struggle to maintain their specific version of Islam in multicultural, post-colonial and post-secular urban settings, exposed to disruptive processes such as gentrification. By applying an ethnographic methodology to comparative urbanism, I aim to shed light on how different spatial transformations affect ritual performances that are meant to protect communities from social disintegration. I argue that different urban policies on both sides of the Mediterranean mutually reinforce, resulting in an overall transformation of cultural practices in transnational communities. Examining how migrants adapt localized ritual practices such
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'NGI Zero Discovery' (NGI0-Discovery), addressing dissemination and exploitation.

assistant: **Impact**

The NGI vision clearly identifies major social and economic challenges that need to be addressed urgently, and articulates a powerful vision for a new phase of the internet. It tries to create an Internet of Human Values, that is resilient, trustworthy and sustainable. The overall mission of the Next Generation Internet initiative is to re-imagine and re-engineer the Internet for the third millennium and beyond.   NGI Zero Discovery aims to provide an agile, effective and low-threshold funding mechanism to enable individual researchers and developers as well as small teams to research and develop important new ideas that contribute to the establishment of the Next Generation Internet. We build on decades of experience to allow clueful and committed people to focus on delivering solutions to important problems.  Unique to our project is that - built on that experience - we will provide a greenhouse environment for the projects and teams that are funded within NGI. Researchers and developers are human too, and the grasp of all relevant best practises they bring along initially is necessarily limited. The demands on technology that should actually run at scale on the modern internet today are huge, and continuously changing. Having the right idea does not automatically mean that you know how to make your solution accessible to blind people, how to set up continuous integration and reproducible builds, how to orchestrate a responsible disclosure procedure, how to make sure that your application can be used with different languages and properly localised, how to engineer secure software and what state of the art attack vectors you would have deal with, how to engage with standards setting organisations, how to nurture and grow a developer community, how to write end user doc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'low Energy COnsumption NETworks' (ECONET).

assistant: **Concept**

Nowadays, it is widely recognised that the sole introduction of low consumption silicon elements will not be sufficient to effectively curb tomorrow's network energy requirements. Based on this assumption, the ECONET project will investigate, develop and test new capabilities for the Future Internet devices enabling the efficient management of power consumption so to strongly reduce the current energy waste.The ECONET project will be devoted at re-thinking and re-designing network equipment towards more energy-sustainable and eco-friendly technologies and perspectives. The overall idea is to introduce novel green network-specific paradigms and concepts enabling the reduction of energy requirements of wired network equipment by 50% in the short/mid-term (and by 80% in the long run) with respect to the business-as-usual scenario.To this end, the main challenge is to design, develop and test novel technologies, integrated control criteria and mechanisms for network equipment allowing energy saving by dynamically adapting the device capacities and consumptions to current traffic loads and user requirements.The ECONET project will focus its research and development efforts in three main research axes:- In the first axis, novel network-specific HW/FW technologies will be developed to optimise the power management features.- The second axis will be devoted to develop local and distributed frameworks for dynamic optimization of the trade-off between energy consumption and network performance.- The last axis will focus on the design of a Green Abstraction Layer for interfacing the novel low-level green capabilities with OAM frameworks in a common and standard way.The ECONET project will deliver novel energy-aware device prototypes on which large-scale demonstration tests will be
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Microbial services addressing climate change risks for biodiversity and for agricultural and forestry ecosystems: enabling curiosity-driven research and advancing frontier knowledge'.

assistant: **Concept**

Terrestrial biodiversity and ecosystems are being challenged by global changes, and threats to agricultural and forestry ecosystems represent some of the most serious environmental and socio-economic menaces that the planet and humanity are facing. Climate change (CG) is widely recognised as one of the most impactful global changes, and since it goes hand-by-hand with biodiversity and services loss in terrestrial ecosystems, they should be tackled together. Microbes constitute the life support system of the biosphere, but they are its most overlooked fraction and are not considered in the context of CG. The overall understanding of the impact of CG on the assembly and functions of microbiomes is still very limited. How the complex microbes-plants-soil interactions and its consequences on plant performance and productivity are impacted by CG is still largely unknown. Additional knowledge also needs to be obtained on the overall ecosystem functioning, and to what extent microbiomes may mitigate stress conditions due to CG. The project MICROBES-4-CLIMATE will provide a wider community of users/researchers, irrespective of location, efficient access to a cluster of complementary world-class Research Infrastructures and their integrated, advanced services along with training and scientific and/or technical support, to address such need. An excellence-driven programme of Transnational Access, which is at the core of the project, will enable users to conduct curiosity-driven research addressing terrestrial biodiversity and ecosystems, in light of the abovementioned multidimensional and still poorly understood microbiomes-plants-soil-environment interactions, and its roles in CG responses, resilience, and mitigation. This will foster the advancement of frontier knowledge and al
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Edible, Medicinal and Aromatic Plants' in the context of a Seventh Framework call.

assistant: **Objectives**

The project is finalized to establish long-term research co-operations through a coordinated joint program of research staff exchanges for short periods on the following topics: selection of plant species according to ethnobotanical and ethnopharmacological approaches; breeding to preserve biodiversity and gene reservation of food, medicinal and aromatic plants; cultivation of food, medicinal and aromatic plant species to improve the quality of the starting material for industrial use (using good agrotechnological guidelines); biotechnological protocols for the production of standardized plant material or for the maintainance of plant species; identification of rural areas which have to be examined as mapped sites and official knowledge degree of the nutraceuticals field; extraction, isolation and structural elucidation of secondary metabolites from plants in order to evaluate biological properties of plant extracts and their bioactive constituents as nutraceutical ingredients with innovative techniques and facilities; development of extraction and quali-quantitative evaluation of plant constituents with medicinal, food, agronomic and industrial interest (bioactive compounds, essential oils, natural aroma, flavour, fragrances, natural dyes); chemical profile of essential oils and volatile fractions for the selection of essential oil from different plant families; development and validation of bio-analytical methods devoted to biomarkers and active compounds in plant extracts; evaluation of antibacterial, antioxidant, cytotoxic, genotoxic, mutagen and antimutagen, apoptotic activity of plant extracts and derivatives; structure-activity relationship studies on standardized extracts or new bioactive compounds isolated from the selected plant material; Emi- or total synthes