RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'FERBOPO – FOSTERING EXCELLENCE IN RESEARCH ON STATE-CHURCH-BODY POLITICS' (FERBOPO).

assistant: **Concept**

The FERBOPO proposal aims at building a new research group at Lucian Blaga University of Sibiu (LBUS) focused on the complex relationship between State, Church and Body Politics that would foster excellence in social sciences and better integrate LBUS in the European Research Area (ERA). To this end, LBUS will create a CHAIR position for Professor Lavinia STAN from St. Francis Xavier University (Canada), whose outstanding academic profile and thorough expertise in the cross-cutting fields of government, religion, economics and epistemology that foster (de)colonial feminist thinking (Lugones, 2010; Manning, 2021) and the institutionalisation of Gender Studies in Romania (Turcescu and Stan, 2005; Stan, 2010) will help increase the number of excellent research staff and improve their capability to attract competitive research funding with significant spill-over effects at societal level, while also assisting LBUS to implement institutional reforms that both align with ERA priorities and facilitate the implementation of the Gender Equality Plan (GEP). The main objective of this FERBOPO is to create a ‘pocket of excellence’ in LBUS by attracting outstanding scientists with internationally mobile academic careers so as to improve the host institution’s organizational culture and the academic outputs of LBUS scholars. Romanian higher education institutions continue to lag behind their Western counterparts in their governance effectiveness and academic performance indicators (Dobbins, 2017). An acute scientific production deficit is related to Gender Studies (Vlase and Terian, 2023). By creating the new chair and research group, the proposed ERA Chair will help LBUS to near European standards of academic performance and institutionalisation of Gender Studies. Through the employ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'ADVANCED (700°C") PF POWER PLANT"' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

In accordance with the energy, environmental, and social policy stated by the EU Commission and the national Parliaments in the participating countries there will be a need for further development of the technologies for power and heat generation in an environmentally balanced way for example by developing clean technologies for utilising solid fuels.This project will result in the demonstration of an advanced PF technology for power generation with efficiency greater than 55%. This improved level of efficiency will give economic and environmental advantages over current power generation technologies. The technology will be primarily based on coal but will be applicable to other fuels such as biomass. During the conceptual feasibility work one or more process designs will be completed. Feed-back from the demonstration phase will produce valuable information about construction, commissioning and operation of a USC plant.The demonstration programme has the overall objective to end up with a fully developed and demonstrated pulverised coal-fired power plant with very high efficiency. To achieve this goal, the project has been divided into the following phases :phase 1 : Designphase 2 : Manufacturingphase 3 : Erectionphase 4 : Commissioningphase 5 : MonitoringThis application covers the first part of Phase 1 (6 years). The total duration of phase 1 is 9 years.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Payoff-Based Decision-Making'.

assistant: **Concept**

This project investigates the effects of personal payoff experiences on subsequent decisions in repeated settings under uncertainty with feedback. The project will first build a theoretical framework integrating the effects of experienced payoffs on both risk attitudes and beliefs. In the model, payoffs influence risk preferences, relaxing the assumption that preferences are stable; payoffs also distort information processing, causing belief biases. I will model this as an individual investor’s portfolio choice problem, and generate implications for behavior and for asset price dynamics. The theoretical results will be tested experimentally and empirically. I will use one experiment to establish the validity of theoretical predictions in a controlled setting where payoff experiences vary across treatments, with all other things equal. The other experiment complements the first by disentangling the competing preference and belief mechanisms with the help of brain scanning technology. Finally, the external validity will be checked in an empirical study using individual investors’ trading and pension choices data. The data contain survey results of investors’ beliefs towards own investments and the market, providing a natural ground for a test of my theory. Understanding of the payoff-based decision-making mechanism in finance can potentially shed light on other behavioral patterns in financial decision-making, such as herding and style investing. This project will thus generate important policy implications for individual investors to improve their welfare, for financial firms to make profits, and for policy makers to enhance market efficiency.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Towards more accessIble and iNCLUSIve mObility solutions for EuropeaN prioritised areas'.

assistant: **Concept**

The main objective of the INCLUSION project is to understand, assess and evaluate the accessibility and inclusiveness of transport solutions in European prioritised areas, identify gaps and unmet needs, propose and experiment with a range of innovative and transferable solutions, including ICT-enabled elements, ensuring accessible, inclusive and equitable conditions for all and especially vulnerable user categories.INCLUSION will address a large set of case studies (at least 50) involving different forms of geographical areas and transport contexts, demographic categories, population groups and mobility solutions, providing concrete experiences from various European sites and pilot initiatives involving a variety of regulatory and business frameworks, supporting technologies, organisational and operational conditions.  Complementary to this, a number of innovative solutions will be concretely tried out and validated through real-life experiments (Innovation Pilot Labs) in a mix of urban, peri-/sub-urban and rural target areas in Belgium, Germany, Hungary, Italy, Spain and the UK, offering a variety of different transport environments, socio-economic contexts, cultural and geographical conditions.Expected results include: an understanding of the main challenges affecting transport provision and accessibility in the different type of prioritised areas; a structured view highlighting the dependencies among spatial and environmental characteristics, populations segments and their mobility needs; in-depth examination of 10 innovative PT approaches and a wider catalogue of at least 40 promising cases contributing to more accessible, inclusive and equitable transport solutions, complemented by innovative solution components validated in real-life experiments; a set of recommen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'PErvasive Computing in Embedded Systems' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The overarching goal of the PECES project is the creation of a comprehensive software layer to enable the seamless cooperation of embedded devices across various smart spaces on a global scale in a context-dependent, secure and trustworthy manner.<br/>The increasing number of devices that is invisibly embedded into our surrounding environment as well as the proliferation of wireless communication and sensing technologies are the basis for visions like ambient intelligence, ubiquitous and pervasive computing. The benefits of these visions and their undeniable impact on the economy and society have led to a number of research and development efforts. These include various European projects such as EMMA or AMIGO that develop specialized middleware abstractions for different application areas such as automotive and traffic control systems or home automation. These efforts have enabled smart spaces that integrate embedded devices in such a way that they interact with a user as a coherent system. However, they fall short of addressing the cooperation of devices across different environments. This results in isolated 'islands of integration' with clearly defined boundaries such as the smart home or office.<br/>For many future applications, the integration of embedded systems from multiple smart spaces is a primary key to providing a truly seamless user experience. Nomadic users that move through different environments will need to access information provided by systems embedded in their surroundings as well as systems embedded in other smart spaces. Depending on their context and on the targeted application, this can be smart spaces in their vicinity such as 'smart stores' or distant places with a specific meaning such as their home or their office or dynamically changing plac
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'The design and development of efficient biocatalytic cascades and biosynthetic pathways for the sustainable production of amines' (BIOSUSAMIN).

assistant: **Innovation**

The objective of this project is to design and develop biocatalytic cascades, using purified enzymes in vitro, as well as biosynthetic pathways in whole cell microbial organisms. These biocatalytic cascades and biosynthetic pathways will be developed for the synthesis of chiral and achiral amines that are of particular interest for the chemical industry. The amine functionality will be introduced using amine dehydrogenases (AmDHs) as biocatalysts in the pivotal core enzymatic step. AmDHs are a new class of enzymes that have recently been obtained by protein engineering of wild-type amino acid dehydrogenases. However, only two AmDHs have been generated so far and, moreover, they show a limited substrate scope. Therefore protein engineering will be undertaken in order to expand the substrate scope of the already existing AmDHs. In addition, novel AmDHs will be generated starting from different wild-type amino acid dehydrogenases as scaffolds, whose amino acid and DNA sequences are available in databases, literature, libraries, etc. In particular, protein engineering will be focused on the specific chemical targets that are the objectives of the designed biocatalytic cascades and in addition, screening for more diverse substrates will also be carried out. Finally, the AmDHs will be used in combination with other enzymes such as alcohol dehydrogenases, oxidases, alkane monooxygenases, etc., to deliver variously functionalised amines and derivatives as final products with elevated yields, perfect chemo- regio- and stereoselectivity, enhanced atom efficiency and minimum environmental impact. Such an approach will be realised through the design of new pathways that will convert inexpensive starting materials from renewable resources, encompassing the internal recycling of redo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Flywheel energy storage for wind power generation'.

assistant: **Concept**

With the ongoing attempt of the European Commission to reduce CO2 emission and protection of the environment, renewable energies will become more and more important. It is not unlikely that renewables will supply 20 - 50% of the global energy demand in the middle of the next century. Integration of such a large amount of renewable energy in the current grid will however cause several problems due to the irregular output. The more remote the point of connection is from the source to the low voltage grid, the greater the disturbance in the network caused by these fluctuations. Modern turbines use the flywheel effect of the rotor to avoid the sudden large step-changes in output to the local network. More efficient use of the generated power can be made if an energy storage device is used. Photovoltaic cells present an even larger problem due to the larger and more frequent fluctuations in output. A recent study showed that increasing the share of photovoltaic energy above 2.2% would present problems to the Dutch grid. Energy storage combined with renewables would increase the firmness" of the renewables supply and would decrease the need to connect them to a strong high voltage grid. The energy storage device could act as a power quality improvement device, importing power of whatever quality and exporting power of assured quality into the grid. Electromechanical energy storage in flywheels is a very good option for short term storage of renewable energies such as mentioned above. The benefits of flywheels over batteries are that flywheels are more compact (higher energy storage density) and they can be discharged totally on a regular duty cycle without causing damage to the system or foreshortening of the useful life. Flywheels furthermore require little maintenance offer
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Protease‐guided tumor targeting tools to revolutionize cancer diagnosis and treatment.'.

assistant: **Concept**

Europe has a high cancer burden: in 2020, 2.7 million EU citizens were diagnosed with the disease and 1.3 million lost their lives to it. This toll is expected to increase further, mainly because Europe's population is ageing: by 2035, cancer will be the leading cause of death in the EU. In 2021, the EC published its ‘Europe's Beating Cancer Plan’ (EBCP), calling for a big push in cancer research. Cancer diagnostics and therapeutics should rapidly become more effective and selective, patient-friendly and personalized.All these goals are directly addressed by developing better tumor targeting strategies. Typically, they consist of equipping diagnostics and therapeutics with a vector unit. The vector unit binds to a protein that is overexpressed on cancer cells or in the Tumor Micro-Environment (TME), causing the diagnostic or therapeutic payload to accumulate in the tumor. Over the last decades, huge effort has gone in approaches that use antibodies as vectors, but return-on-investment has overall been rather poor. Exciting, recent innovations rely on small molecule vectors that target TME proteases. Proteases are ideal candidates for tumor targeting: they are often strongly overexpressed in the TME and possess an active site that allows high-affinity anchoring of vectors. Members of this consortium have played a leading role in these developments.OncoProTools wants to force breakthroughs in cancer diagnosis and therapy by:1) Exploring innovative venues for protease targeting in CAR T cell therapy. 2) Discovering novel vectors that bind to other TME proteases: cathepsins S, B, L and granzyme B3) Personalize applications of protease targeting: deliver innovative diagnostics through deeper understanding of TME biology.At the same time, OncoProTools will deliver a training
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Epithelial-mesenchymal crosstalk in the pathology of influenza virus infection', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Influenza virus infects the airway epithelium. The connective tissue underneath the epithelium consists of extracellular matrix (ECM) produced mainly by fibroblasts. Small airway fibrosis, characterized by fibroblast activation and excessive deposition of ECM, is emerging as the key driver of the progression of chronic obstructive pulmonary disease (COPD), a very common and life-threatening lung disease for which no cure exists. Irreversible progression of COPD is often triggered by influenza virus infection. However, causative mechanisms between influenza virus infection and small airway fibrosis have not been explored. In this project, the fellow will infect an advanced co-culture model of patient-derived airway epithelial cells and fibroblasts from the human lung to mimic the microenvironment of the airway. Cellular and molecular profiling of the fibroblasts will be performed by an unbiased approach using integrated and interdisciplinary methods. Especially, a unique mass spectrometry and bioinformatics workflow for deep molecular profiling of the ECM will be combined with state-of-the art single cell RNA-sequence analysis to discover profibrotic readouts. Then, she will use cells from COPD patients to translate the findings to the clinic. Finally, she will establish a host-gene specific knockdown co-culture model to elucidate the role of a specific protein that interacts with the ECM and assess the druggability of this potential target. The fellow is a pathologist from Japan with extensive experience in infection with animal models. Her expertise and knowledge in disease pathology will be integrated with the host's prestigious scientific environment. Establishment of international connections will facilitate her to become an academic leader with a unique and multidi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Development of new nanocomposites using materials from mining industry', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Silver nanoparticles  and silver based nanostructured composites  are being frequently used in a variety of biomedical and  industrial applications, such as an antimicrobial agents,   lead-free solders, electric contact materials, gas-sensitive sensor, etc. The most complicated Silver using problems are related to: i) recovery of silver from ore waste materials; ii) the controlled synthesis of metal nanoparticles of well-defined size, shape and composition; iii) nanoparticles incorporation to desired implant surfaces; iv) synthesis of Silver based nanostructured composites for industrial purposes. The main goal of the Project is to develop:1. Clean and efficient procedure of silver recovery from waste: Combined Mechanical Activation – Thermal Oxidation Processing jarosite type residues to alleviate and accelerate the following precious metal leaching;2. Combined  nanotechnology of biological synthesis (use of plants for the nanoparticles synthesis) of Ag nanoparticles and its deposition on implant surfaces by electrophoretic and plasma spraying deposition;3. Nanostructuring technology of Silver based nanocomposites manufacturing for electrical contact applications.Pilot production and trials of developed Ag nanoparticle modified implants and Ag based nanostructured composites:1. TiO2 and Hydroxyapatite Ca10(PO4)6(OH)2) coated implants which are widely used in orthopaedic surgery because of their good biocompatibility related to the osteoconductive properties of calcium phosphate coating;2.  Ag-SnO contacts for electrical systems; these composites combine high resistance to welding and to electric arch erosion of the refractory phases with the high electric and thermal conductivities.