RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Role of nef protein in cell biology of hiv-1 infection' (1994-1998).

assistant: **Innovation**

Research objectives and content A functional Nef gene is critical for the capacity of primate lentiviruses (HIV-1, HIV-2, and SlVs) to cause AIDS, but the relevant cellular functions and the molecular mechanisms of action of Nef are still unclear. Recent evidence, in particular the physical and functional SH3 domain-mediated binding of Nef to host cell protein tyrosine kinases, indicate that Nef functions by modulating cellular signal transduction pathways. The Src-family tyrosine kinases Hck and Lyn bind tightly to Nef, and in the case of Hck this interaction has been shown to result in induction of the catalytic activity of this tyrosine kinase leading to cellular activation and malignant transformation. Since Hck and Lyn are highly expressed in myeloid cells, these observations suggest that these proteins may be important mediators of the pathogenic function of Nef in HlV-infected monocyte/ macrophages in vivo. Functional studies on Nef-mutants which lack a functional SH3-binding site also suggest an important role for Nef/SH3-interactions in other cell types, including T cells, the principal target cells of HIV infection. However, despite a number of host cell proteins suggested to interact with Nef, a protein expressed in T-cells and showing Hck-like high-affinity SH3-mediated binding to Nef remains to be identified. Discovery of such a protein would be a major advance in understanding the biology of Nef and pathogenesis of HIV infection. Training content (objective, benefit and expected impact) We have developed and successfully validated a system based on screening of gt11 lambda phage cDNA expression libraries with radiolabeled recombinant GST-Nef fusion protein. The aim of this postdoctoral project and the subject of this proposal is to utilize this system to i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'European project for the development of HTR technology - materials for HTR' (HTR-M) targeting Fifth Framework.

assistant: **Abstract**

The development of Advanced High Temperature Reactor (HTR) concepts requires material data information and an understanding of material behaviour under reactor operating conditions and environment. For components important to the safety and feasibility of designs such as the main steel structures (vessel, internal structures, turbine) and the graphite structures (core), investigation of the different materials to be used and their behaviour in the reactor environment is an important and necessary requirement. This work identifies and investigates the most promising materials and provides an HTR database of information for the materials of the key components that can be used by designers for feasibility investigations of the most promising options for future application.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Making Energy Efficiency First principle operational' (ENEFIRST) targeting Horizon 2020.

assistant: **Abstract**

"Efficiency First"" (E1st) is a fundamental principle applied to policymaking, planning and investment in the energy sector, which is gaining visibility in European energy and climate policy. ENEFIRST will help making the E1st principle more concrete and operational, better understand its relevance for energy demand and supply and its broader impacts across sectors and markets, focussing on the buildings sector. Its main objectives are to define the principle of E1st in practical terms, assess how it has been applied internationally and how it applies to the EU context, to assess the value of applying E1st across different policy areas for buildings’ end-use energy efficiency and to quantify the impacts of increased building energy efficiency for the future energy system in the EU, and to identify key policy areas for the application of E1st and develop policy proposals for its implementation in the EU Buildings Sector. The methodology of ENEFIRST has been designed in light of the novelty of the approach informed by a deep understanding of the current energy policy landscape and the existing practices of energy efficiency policy making and is based in three pillars a) identification of the most relevant policy areas where the E1st principle can be applied to achieve the highest impact in terms of energy system benefits, through screening 5 areas of potential application, modelling three scenarios and five modelling case studies and applying the E1st in three regions in the EU, b) application of the E1st in policy instruments, through assessing the applicability and transferability of international E1st approaches and quantifying the impacts of E1st (through modelling and multi-criteria analysis), and c) application of E1st through the design of policy instruments and th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'TURN ON THE LIGHT ON SCIENCE' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

LIGHT’09 is a “cultural transformation event” bridging the gap between contemporary researchers and people who will ultimately benefit from their work. LIGHT’09 conducts visitors on a journey into today’s science and technology, giving them reasons to get excited about the future and changing the image they have of scientists and science. The main objective of LIGHT’09 thus consists of changing the image of scientists and science through bringing researchers and public at large closer to one another.Moreover, LIGHT’09 is a fun yet informative festival throwing the spotlight on science and the “human face” of scientists. It also encourages younger people to get into science, engineering and technology and turn it into a “cool” career.While last year the focus was on the five senses, LIGHT’09 relies on the four elements, namely: air, water, fire and earth.The main location will be the Rome Planetarium. LIGHT’09 intends to sensitise the participants to the existence of gender stereotypes reducing the access and permanence of women to scientific careers. This sensitisation will be illustrated through the establishment of two different and separated entrances for men and women.  As a consequence of this specific objective, gender balance will be considered in selecting the researchers who will be protagonists of the RN.The event will last from 3 pm on 25th September to 2 am of the following day. The LIGHT’09 project will last seven months.A purposely designed communication strategy will support LIGHT’09 so to ensure its success.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Copepod mate-finding behaviour - mechanisms and ecological implications', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

The few existing studies on mate finding in copepods indicate that both chemical and hydro mechanical signals are involved in the remote detection, identification, and pursuit of mates. The objective of the proposed project is to describe mate-finding behavior in the copepods Acartia tonsa, Pseudocalanus sp., Centropages typicus, Centropages hamatus, Oithona similis, and others. These species are abundant in the ocean and therefore of strong ecological interest. We will describe the spatial and temporal swimming patterns during mate finding, and investigate the type of signals (chemical or hydro mechanical) used. We shall conduct experiments testing male reactions to artificial signals, and test signal persistence. Moreover, theoretical analyses of signal generation, propagation, and perception will be made. The results obtained from the descriptive studies, the signal experiments, and the theoretical analyses of signals, will be used to model encounter-rates and examine population-dynamic implications in natural populations. A brief summary of the specific project-activities and methods includes:a) Describe and visualize mate-finding behavior in a series of marine copepods by use of 3D video-filming andimage/motion-analysis.b) Identify the types of signals used for mate-finding by video-analysis of spatial and temporal swimming patterns.c) Perform experiments testing effects of artificial chemical and hydromantic signals.d) Test signal persistence in differing environments e) Make theoretical analyses of signal generation, propagation and perception.f) Use the results of the previous activities to model encounter -rates, and examine population-dynamic implications in natural populations. Training content: The proposed project will provide training in use of 3D video-an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Three Phase Cable Tester' (1994-1998) under Fourth Framework.

assistant: **Objectives**

To develop an advanced design CL automated Cable Tester incorporating a high degree of novelty in its approach to performing tests to the requisite British and International standards. Aimed at the Cable Manufacturer, the tester will make Large cost savings on time and by reducing energy consumption. The proposed project meets the RTD goals relevant to the Standard Measurements and Testing Programme. The Research will be a collaboration between RTD performers and industrial SME's to transform the theory into a practical solution. In addition to the proposer companies it is planned to involve a European transformer manufacturer, software development company and a major cable manufacturer.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Strengthening the Research and Technological Capacity in the Field of Nanostructured Thin Films, Hard and Superhard Coatings' (RTCNANOHARD) targeting Sixth Framework.

assistant: **Abstract**

The project is aimed to afford an opportunity for the scientists from the Institute of Applied Physics (IAP) in consolidating of the knowledge on the nanostructured thin films, hard and superhard coatings and to improve the related technological capacity. Nanostructures have been successfully applied in the new device generation of the modern microelectronics, whereas superhard coatings based on nanostructured films are widely used in many areas of the advanced industry. Hence the understanding of the growt h mechanisms and the properties of nanostrucred films are of great importance. IAP has wide experience in the technology and characterisation of thin films for semiconductor devices. This work is well known between the European researches and gives an appr oved position of IAP in the power semiconductor device community. The project will strengthen the established collaborations and the further progress in this field.Last two years the scientists from IAP have been working intensively on hard coatings for cu tting tools developing technology and PVD equipment in replay to the needs of Bulgarian industry and orders received outside the country. The further progress of these activities needs close collaboration with the leading research groups in that area. The goal of the project will be achieved by exchange visits of scientists from IAP and leading European groups during which lectures and joint experiments will be realised. International workshops and a conference will be organised forward the dissemination of the knowledge on nanostructured thin films, hard and superhard coatings. The renewal of the equipment will improve the technological capacity in accordance to the new requirements. The project realization will create beneficial relations with the European scie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'SUstainable Real Estate 2050' in the context of a Horizon 2020 call.

assistant: **Objectives**

Sustainable Public Real Estate Management (SPREM) is almost non-existent in Flanders (BE). SPREM can be defined as the management – i.e. acquisition, holding, using and disposing - of real estate assets in such a way that it realises ambitious sustainability goals, minimises the total costs of ownership and life cycle costs and maximises the benefits of real estate for the community. The absence of SPREM is a major barrier for large scale sustainable energy investments in public buildings in the short, medium and long term in Flanders. This barrier has consistently been identified by SURE2050 consortium partners supporting public clients with energy efficiency services as well as by municipalities themselves, including the more than 95 municipalities that indicated their strong interest in SURE2050 via a Letter of Support.  SURE2050 will remove this barrier by providing SPREM-training, SPREM tools and coaching to municipalities and to regional governmental organisations in Flanders. SPREM will generate critical information for strategic decision making, such as reliable quantitative and qualitative data on buildings, energy renovation potential and the use of resources. Thanks to the long-term SPREM vision, shorter term energy efficiency investments can be made without causing any lock-in effect for the future. A broad consortium of public and private partners has been created to maximise the involvement of these public organisations in the programme and to support them with the implementation of SPREM in their organisation, as well as with the concrete sustainable investment projects with a minimum value of 20 million EUR.As the absence of SPREM is not limited to public organisations in Flanders, the SURE2050 proposed project will also have a high added value for most
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Illuminating every sound with lasers, coding words and complex sounds with light.' (LIGHTCODESWORDS) targeting Horizon 2020.

assistant: **Abstract**

An estimated 360 million people worldwide are living with disabling hearing impairment. This number is rising mainly due to a growing global population and longer life expectancies and increasing noise exposure. Unaddressed hearing loss poses an annual global cost of 750 billion international dollars. Interventions to prevent, identify and compensate or cure hearing loss are cost-effective and can bring great benefit to individuals. Currently available auditory prostheses based on mechanical or electrical energy are not sufficiently supplying the hearing impaired population. The main reasons are insufficient frequency specificity, feedback and discomfort due to occlusion effect and/or recurrent auditory canal inflammations. Light is a form of energy that can be very well focused, can be applied without the need of direct contact and may be the alternative energy for the stimulation of the hearing organ. With our LaserHearingAids Starting Grant we have developed a novel activation strategy of each individual frequency of the hearing spectrum using monochrome laser pulses. It has the advantage of a non-contact, very precise energy transfer in vibratory structures and shall be used to improve hearing and further auditory pathologies. In preparation for the prototype of the optoacoustic auditory prostheses we will continue testing the market, build up the started cooperation with industry partners and ask for ethical approvals for the first clinical studies. In parallel we will work on to coding speech and more complex sounds like e.g. music using the optoacoustic vibrations and improve loudness modulation within the biocompatibility margins. Our laser based coding strategy will revolutionize the auditory prostheses by replacing the speaker or the sound transducer with lase
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Optimal use of healthcare resources through AI-guided support of healthcare professionals' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

MedicalExpress (ME) is an AI-based innovation that optimises patient flow processes. It is a B2B solution for healthcare providers, developed to generate added value for patients and caregivers alike. ME is the result of 10 years of R&D together with clinicians, nurses and input from collaborators from academia, IT and pharma (e.g. Yale, Johns Hopkins, UCLA, ETH Zurich, Novo Nordisk and Sigma).electoME is currently implemented in 30% of Sweden’s public primary care, where is has proven to allow each general practitioner (GP) to see 50% more patients/day, generating cost savings on the order of €100 000 per GP/year. By increasing efficiency, ME increases access to care, improves patient safety and generates cost savings not only for payers, but also by decreasing work absenteeism.  Our offer is completely unique and the only CE-marked solution of its kind in Europe. ME is a comprehensive modular platform, which seamlessly integrates into existing IT structures and EHR (electronic health records). Being modular, ME can be fully customised to meet specific client needs. ME doesn’t replace jobs and retains diagnostic decision-making with experienced healthcare professionals. Our AI augments personnel in compiling and analysing data, creating reports and supporting decision-making in a way that liberates vital time that can be spent on tending after the patients. Having won several public tenders in competitions with international e-Health providers, we have demonstrated ME to be a great market fit as well as the most attractive solution to the prevailing resource management problem.  In the project, we will roll out the solution for several new market segments and launch or product throughout Europe and the US. The project will take our market-validated solution through a r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'A direct route to produce solar grade silicon at low cost ('SOLSILC')' (SOLSILC) targeting Fifth Framework.

assistant: **Abstract**

Objectives and problems to be solved: General objective of the project is to research and develop the new two-step high temperature plasma-process for solar grade silicon (sog-Si) production, to test the processing and efficiency of SOLSILC cells, to evaluate an approach for scale-up and to investigate relevant technical, environmental and economical aspects. After the SOLSILC project a pilot demonstration on scale (2 years) is anticipated, in order to achieve a market price of 10 Euro/kg sog-Si in a full-scale plant of 5.000 tm/y in 2005. The new sog-Si process was developed and studied by the Norwegian and Swedish partners and evaluated by the Dutch partners. The perspective of this process (low-energy, high yield, low impurities, experience with other metallurgical processes, direct route) is a low cost sog-Si of constant quality in sufficient quantities. The project relies on expertise of Si, Sic, metallurgical and PV cell processing of the R&D partners, in combination with the exploitation expertise of the market partner. Description of work: The work consists of process optimisation, product evaluation (PV cell efficiencies) and technical, economical and environmental evaluations of a follow-up approach. The work has been divided in technical work packages (at 3 R&D locations) and supportive work packages. Development of low-purity Si-process facility, including raw materials selection and supply and development of a Si refinement process for the removal of carbon.2. Testing of low-purity Si-process. A test facility will be built to test and optimise the two- step Si production process. The work includes modification of a specific plasma torch.3. Production of artificial solar grade silicon for preliminary testing of the process with respect to its performance in