RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Tackling Idleness and Under-utilization of Heavy-Machinery with a new fully Automated and Versatile Docking System' (DOCKNROLL).

assistant: **Innovation**

30-40% of all heavy machinery is standing idle while the motor is running which is a major waste and health hazard, but there are currently no solutions to address this problem. Major causes of idling are 1)specialized machines not being utilized due to seasonality: besides having to cope with the maintenance of these machines, users may have to look for others when needing a different application;2)the driver having to leave the cabin and dock the vehicle to attach components manually (time & cost-intensive, unsafe process), while the engine is running. We, SYN TRAC GmbH are an Austrian start-up company founded with the aim to bring to the market a solution that would tackle both problems described - DOCK’N’ROLL. DOCK’N’ROLL is a heavy machinery vehicle which can be indefinitely augmented with customized attachments (crane, snow plower, etc.) through our innovative docking system (patented). Heavy machinery operator companies can finally have access to a fully transformable vehicle, which can rapidly couple with attachments depending on the desired application, at the same time it provides safety to drivers. Also, it is built to provide the highest performance and reduced emissions and is the only vehicle that provides full docking automation. We have now finished producing our first prototype and signed our first customer deal. Through this project we seek to finalize DOCK’N’ROLL’s development, to prepare the scale-up of our production from 20 to 50 units/year to meet our confirmed demand in European countries, as well as to consolidate our supplier and distributor network. In November 2017 we made our first appearance at the World’s leading International Fair of the Sector – Agritechnica – rendering 360 contacts and +150 leads from European companies. This confirmed
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Towards Excellent Robotics and Artificial Intelligence at a Slovak university', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The TERAIS project aims at transforming the Department of Applied Informatics (DAI) at COMENIUS UNIVERSITY in Bratislava (UKBA) to a workplace of international academic excellence and an outstanding example for other HEIs in Slovakia. To achieve this, the project aims to: (1) prepare conditions for systematic development of human capital and research capacity of DAI UKBA, (2) establish sustainable networking and collaboration links with partner institutions/within UKBA, (3) boost scientific profile of DAI towards mitigating the research and innovation gap, (4) establish institutional research support structures at UKBA. The partnership will comprise, in addition to DAI UKBA, the Knowledge Technology team at UNIVERSITÄT HAMBURG in Germany - with exceptional expertise in neural networks, deep learning and crossmodal learning for developmental robotics - and two units at ISTITUTO ITALIANO DI TECNOLOGIA in Italy - with excellent experience in humanoid robotics, control using physical and simulated robots and human-robot interaction. The project will be based on 4 pillars: (1) PEOPLE - aiming at creating a life-long career development system at UKBA; (2) NETWORKING - focusing on strengthening collaboration links with international partners and the business community; (3) RESEARCH - focusing on cognitive robotics, a part of embodied artificial intelligence, in which all project partners have outstanding expertise; and (4) SUPPORT - directed towards building the necessary research support structures at UKBA. The project will leverage a broad range of channels, such as staff/student exchanges, joint events/proposals/publications and specific dissemination/communication tools. The project is expected to contribute to promoting research excellence at different levels (UKBA: DAI,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Biological micro analysis of bacterial pollution for real time analysis of surfaces' under Fifth Framework.

assistant: **Concept**

The project will endeavour to advance the technology of microbiological assessment by using advanced biotechnology coupled with new manufacturing techniques to greatly increase the speed of testing for bacterial pollution. The device will consist of an adhesive biopolymer-sampling element for swabbing the surface, which will be assessed for bacterial loading very rapidly. A risk assessment will then determine if a bioassay needs to be completed. The bioassay will determine the type of pollution, by species such E.coli0157 or Ps.aeruginosa, and the viability and total bacterial loading. The device will consist of a micro-fluidic based biochip with optical and electronic components, which measure m-RNA, phosphataseactivity and total protein. Hence the project will deliver a device that assess, biological assurance by 4 processes; bacterial loading, viability of cells, identificatlon of species and bacterial pollution risk factor.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Tilt Rotor Heat Exchanger' (TiltHex) under Horizon 2020.

assistant: **Objectives**

The overall objective of the project is to design, develop; manufacture and flight qualify a novel heat exchanger for oil cooling in the transmission system of a civil Tilt Rotor aircraft.  The proposed solution will outperform a conventional plate-fin heat exchanger in terms of efficiency, volume, weight, robustness, reliability and will fully integrate into the transmission systems architecture. The concept underpinning this project is to build upon Marston Aerospace’s long history of innovation within heat transfer and fluids management systems by forming an integrated project team.  The team will consist of thermal modellers, mechanical design, manufacturing, experimentalists and R&D experts in order to propose three initial air cooled oil cooler designs based on different manufacturing technologies.  These will be conventional plate and fin corrugated heat exchanger; chemically etched plate and pin and an additive layer manufacturing solution utilising a novel architecture.  An assumption would be that the material which would be most appropriate, in terms of technology readiness and for each proposed manufacturing process the suitability would be aluminium and that the new designs will be directly compared to each other in order to select the most viable design to take forward through to prototype manufacture towards flight demonstration testing.


**Keywords:** Heat Exchanger, chemical etching, additive layer manufacturing, air cooled liquid cooler
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Evolution of LNA Aptamers' (EVOLNA).

assistant: **Innovation**

Aptamers are single-stranded oligonucleotides which are able to target peptides, proteins, small molecules or live cells by virtue of their well-defined three-dimensional shapes. Aptamers are typically generated by evolution of specific sequences against a given target by in vitro evolution using the process known as SELEX. Progress of this field with respect to drug development has so far been hampered by the relative large size and poor biostability of evolved aptamers composed of unmodified nucleotides, necessitating tedious and extensive post-SELEX truncation and modification approaches. LNA (locked nucleic acid) is a prominent nucleotide modification which is in the process of revolutionizing gene silencing and RNA detection. LNA however has never been included in de novo aptamer evolution. EVOLNA is an ambitious but coherent research program with the objective of transforming the field of aptamer technology. The vision is to enable evolution of aptamers that per se possess most of the desired properties, thereby alleviating the need for extensive post-SELEX procedures. This will be realized by combining the unique properties of LNA with innovative methods for LNA aptamer evolution. LNA aptamer technology is envisioned to enable evolution of aptamers displaying maximum chemical diversity, minimum size and high biostability. The developed strategies will be applicable not only towards evolution of therapeutic aptamers, which will be the main subject of this program, but also towards evolution of aptamers for biosensing, diagnostic and imaging applications. The program is at the very frontier of biotechnology research and spans the areas of chemistry, molecular biology and drug research.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Evolution equations for composite operators and AdS/CFT integrability' (IEET2).

assistant: **Concept**

Quantum field theory gives the excellent description for the electromagnetic, weak and strong fundamental interactions by means of perturbative expansion in the coupling constant. It allows to obtain results, which can be compared with experiments. In some cases the large logarithms are appeared in perturbative calculations and they should be sum exactly, i.e. in all orders of perturbative theory. Arising evolution equations are widely used for the theoretical description of the high energy scattering processes, which extensively studied at LHC and other experiments at colliders. During forty years of investigations a lot of remarkable properties related with these evolution equations were found. In particular, as the most important, the connection between high-energy scattering and the exactly solvable two-dimensional field-theoretical models was discovered. The similar integrability was discovered under investigation of composite operators in the planar limit of the famous AdS/CFT-correspondence. In this project we are going to extend the investigations of integrability for other evolution equations in the framework of planar gauge/string duality and beyond planar limit within the collaboration between Applicant as expert in considered evolution equations and the Research Group from Host Institute as experts in AdS/CFT integrability. We shall calculate the higher-loop anomalous dimensions of composite operators and study their properties. Obtained results will used for the test of available and the development of new methods.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'COATING - slippery wires: revolutionizing COronAry sTentING' (COATING) targeting Horizon 2020.

assistant: **Abstract**

COATING aims at developing cutting-edge technology for the reduction of stent thrombosis and restenosis events, based on a multidisciplinary approach linking fluid mechanics and biomedical engineering. Principles of fluid mechanics will be combined with nanotechnology to advance our understanding of the physics of drag reduction and exploit this to establish a novel biomedical engineering application. The nanotechnology is based on magnetorheological fluids, also called ferrofluids (FFs). Specifically, FFs will be used as a lubricant for the reduction of harmful wall shear stresses generated at the coronary stent surface. The objectives are, firstly, to evaluate the performance in terms of magnetoviscous effects of various biocompatible FFs varying shear and magnetic field strength. Secondly, we will evaluate the FF-based drag reduction by performing extensive FF-coated pipe flow experiments. Finally, we will evaluate the efficiency of the novel drag reduction technique in stents in vitro. The project will be hosted at WSL, Switzerland, which is part of the ETH domain, a world leading and closely cooperating network of research institutes, and will be integrated in a young and dynamic research group, offering a cutting-edge laboratory and excellent opportunities for career development.The proposed technology strives to complement or even replace adjunctive pharmacological treatments usually adopted after stent implantation, which often have significant harmful side effects. It has the potential to improve the quality of life of the millions of patients worldwide that undergo coronary stenting each year, and to provide a new solution for patients in which pharmacological therapies cannot be prescribed. Finally, the project results are also expected to foster other applic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Protein degraders for targeting galectin-8' (PROTAG-8).

assistant: **Innovation**

In the PROTAG-8 project, we aim to target galectin-8 by protein degradation using proteolysis targeting chimeras or shortly, PROTACs. Galectin-8 is a galactoside-binding lectin that exists as a soluble intracellular and extracellular receptor, with an extensive exchange between the membrane-bound and cytosolic forms. Its inhibitors are potential new anticancer drugs, but the affinity of classical galectin-8 inhibitors is in the low micromolar range, hardly sufficient for their use as drug molecules. The overarching aim of PROTAG-8 is to explore whether the PROTAC method can be implemented for galectin-8 and to answer the question of whether PROTACs offer advantages over classical selective galectin-8 ligands. Since PROTACs need only bind their targets with high selectivity and with an affinity high enough to stabilize the ternary complex between the protein of interest and the E3 ligase, the affinity in the micromolar range could be sufficient for their activity, unlike conventional ligands. The current state-of-the-art in the development of PROTACs focuses only on intracellular proteins, but galectin-8 exists as both an intracellular and extracellular protein. Based on this fact, we want to find out whether such a receptor, which occurs both in the cytosol and in the extracellular matrix, can be effectively targeted with PROTACS and its activity modulated. This scientific question will be tackled by a highly-qualified PhD Nives Hribernik with international experience in glycochemistry, medicinal chemistry and chemical biology, and is expected to be an excellent springboard to her independent scientific career. The project proposal includes renowned principal investigators from two academic institutions: Prof. Dr. Marko Anderluh from the University of Ljubljana (Sloveni
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Data-driven Reduction Of Pesticide Spread in high volume orchard treatments with smart sprayers.' (DROPS).

assistant: **Concept**

In fruit tree crops, which are vital to EU agriculture, efficient pesticide use is crucial for maintaining high yields and assuring market quality. However, traditional spraying methods often result in significant pesticide losses through drift and runoff, posing environmental and health risks. Although new smart sprayers equipped with pulse width modulation (PWM) valves are designed to control flow rates and minimise off-target losses, the droplet size variations caused by pressure fluctuations when spraying high volumes to control pests and diseases are still poorly understood, and often lead to uncontrolled pesticide dispersion to the environment. The DROPS project will optimise pesticide application in orchards by developing a novel methodology for predicting pesticide dispersion and improving spraying practices. Specifically, DROPS will directly measure droplet size in orchards and integrate computational fluid dynamics (CFD) models with machine learning to create a Decision Support System (DSS) that guides farmers in optimising pesticide applications. The project will adapt and validate droplet size measurement techniques for dynamic outdoor orchard conditions, using PWM-based sprayers. This will provide accurate data on droplet behaviour under varying environmental conditions and sprayer settings. The data will inform predictive models of droplet size variation, enhanced by machine learning algorithms for greater accuracy. These models will then be integrated into CFD simulations to predict pesticide dispersion in different orchard environments. In the final phase, the DSS will be developed and field-validated to provide real-time recommendations for minimising off-target pesticide dispersion. The system will be implemented in smart sprayers and tested with an in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Microscopic, Mesoscopic, and Macroscopic Approaches to Mitigate Micro- and Nano-plastics in the Food and Environment', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The proposal, Microscopic, Mesoscopic, and Macroscopic Approaches to Mitigate Micro- and Nano-plastics in the Food and Environment (3M-2MNP-FE) is an MSCA PF proposal to be hosted by the University of Malta for 24 months, wherein Dr. Floirendo Flores will be supervised by Dr. Sophie Marie Briffa. Following the 24-month fellowship, a non-academic placement (NAP) has been secured with commitment from Dr. Adrian C. Love (ACL) from AquaBioTech Group (ABT). Dr. Flores conducts research on microencapsulation of bioactive compounds and simulated digestion, whereas Dr. Briffa specializes on nanoparticles chemistry, synthesis, characterization, and environmental behavior. The co-mentor, Dr. Melissa Marie Formosa, has in vivo studies involving zebrafish larvae and currently has supply agreement with ABT. Plastic packaging polymers are a necessary component of food products that are often discarded in municipal solid waste treatment plants and landfills resulting in varying levels of degradation products. The degradation products are usually recalcitrant micro- and nanoparticles (MNPs) that enter aquatic environments and contaminate biota with potentially adverse health outcomes. In view of the pressing need to mitigate the environmental risks upon exposure to MNPs, an interdisciplinary approach combining polymer chemistry, food, nutritional, and animal sciences is being proposed to develop an environmentally sound enzymatic technology to treat MNPs. Enzymatic treatment can change MNP size and enhance biodegradability. New knowledge will be generated on in vitro and in vivo changes on enzyme-based gastrointestinal and antioxidant systems following exposure to enzymatically treated MNPs. Implementation of the work packages will help answer the research question: Does exposure to en
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Top down regulation of motivated behaviors by lateral septal integration of cortico-hippocampal inputs'.

assistant: **Innovation**

How does cognition regulate innate “low-level” behaviors? While the cognitive functions of the prefrontal cortex (PFC) and hippocampus have been extensively studied, we know much less about their ability to regulate the activity of the various hypothalamic nuclei controlling motivated behaviors (sociability, aggression, mating, feeding). Living in society nonetheless requires that our past experiences and decision-making exert some degree of control over our “basic” behaviors. The lateral septum (LS) -receiving inputs from PFC and hippocampus and projecting primarily to the hypothalamus- is ideally positioned to integrate cognitive information and, in turn, regulate motivated behaviors. Thus I characterized in mice a novel circuit by which hippocampal CA2 projections to LS result in disinhibition of an aggression-promoting nucleus of the hypothalamus. I also showed that vasopressin enhances aggression through presynaptic facilitation of CA2 inputs to LS. Using this study as a blueprint, I will determine the logic by which LS integrates and compute cognitive inputs to regulate other motivated behaviors. As motivated behaviors depend on internal states, I will also explore how modulatory inputs (vasopressin, dopamine, serotonin) from subcortical brain regions to LS can regulate its function. Finally, since hippocampus, PFC and LS are implicated in several psychiatric disorders associated with altered social behaviors (schizophrenia, autism or bipolar disorder), insights into how these regions regulate motivated behaviors are critical for understanding both basic neural mechanisms as well as how disease processes lead to altered social interactions. This project therefore also aims to unravel potential changes occurring in disorders associated with social behavioral defici