RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'European Research on Cord Blood Banking and Use for Transplantation'.

assistant: **Innovation**

The principal limitations of allegoric bone marrow transplantation (ABMT) are the lack of suitable HLA-matched donors for the majority of patients and the complication of graft-versus-host disease (GvHD). The lack of sibling donors in some cases has been overcome through the establishment of large panels of potential marrow donors but these panels are restricted in terms of HLA polymorphism and of their ethnic diversity. This is most marked in Europe where each nation has its own ethnic diversity. Limitation is also related to the fact that results of allegoric bone marrow transplantation from normal bone marrow donor are dependent of HLA-A, B, C, DR, DP, DQ identity between donor and recipient. Umbilical cords from full-term pregnancies have been shown to be a source of haematopoetic progenitors (1,2,3,5,6). Banks of cord blood samples are being established in a number of EU member states (47). A number of cord blood transplants have been performed with encouraging results (3,39,40,41,42,43,44). Preliminary evidence suggests that these transplants are associated with less GvHD than comparable unrelated BMT. The purpose of the research is to advance our understanding of cord blood transplantation and to establish common criteria and protocols for the handling of cord blood samples. 1. Objectives - to standardise the methods of collection, testing and cryopreservation of cord blood- to study the properties of haematopoietic progenitors present in cord blood- to study the immune function of cord blood lymphocytes- to co-ordinate and facilitate the exchange of sera and cells from regional cord blood depositories held in member states- to establish a European Registry of patients treated by cord blood transplantation and design protocols comparing cord blood transplants wit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Integrated system for real-time TRACKing and collective intelligence in civilian humanitarian missions' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The enduring humanitarian crisis in the Middle East, the unrelenting high levels of violence in Afghanistan and new outbursts of violence in South-Sudan have made 2014 another record-breaking year for acts of violence against humanitarian aid workers. In 2000 41 significant attacks on aid workers were recorded across the globe. By 2014, that number had risen to 190. In this 15-year period, over 3,000 aid workers have been killed, injured or kidnapped. Despite the increasing availability of tracking and monitoring technologies, the number of humanitarian workers that fall victim to attacks continues to rise. Clearly, a novel and innovative approach to tracking and decision-making is needed.  Information systems for fleet management, GPS for navigation and location or RFID tags for inventory management are just a few of the technologies that have changed the humanitarian operations. Until now, however, there is no integrated decision support system that provides real-time analyses from the data streams that are generated by these technologies.  This lack of integrated real-time information prevents an understanding of potentially threatening situations, increases response times and creates insecure communications, all leading to inadequate protection and hampered efficiency and effectiveness.The aim of better protection and more efficient and effective operations can only be achieved by devel-oping technologies along with the policies for their use. GPS, for example, notwithstanding its capability to provide live tracking of vehicles for recovery, cannot prevent an ambush or kidnapping. Technologies therefore need to go hand in hand with procedures and policies in order to provide useful early warnings to decision-makers on the ground as well as decision support for sched
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Residue Management in the Olive Oil industry: Valorisation and Environmental protection' in the context of a Horizon Europe call.

assistant: **Objectives**

The main objective of ReMOOVE is to study existing and novel opportunities for an integral valorisation of alperujo, a residue from the extraction of olive oil that creates significant environmental impacts. The aim of the valorisation is to obtain compounds and materials of high interest and minimise the environmental impacts associated with alperujo management. The following valorisation routes will be investigated: use of clay and fresh alperujo to manufacture ?green roofs?, recovery of compounds of interest from the liquid fraction of degreased alperujo by thermal hydrolysis, production of low-cost adsorbent materials from the solid fraction resulting from the hydrolysis process of degreased alperujo for the removal of contaminants from wastewater, and production of fuel gas by gasification of the solid fraction obtained from thermal hydrolysis of the degreased alperujo. Once the valorisation processes are defined and have been tested in a laboratory scale, a thorough environmental impact study will be carried out to ensure that the sustainability performance of the proposed alternative is superior than that of the current waste management strategy. For this, the Life-Cycle Assessment methodology will be used to evaluate environmental impacts for all relevant impact categories, from the moment alperujo is obtained until alperujo and all its by-products are managed. A socio-economic assessment and resilience & risk analysis will also be performed in the last stages of the project to ensure the solutions proposed are viable at an industrial scale. It is expected to integrate the alperujo valorisation processes into the olive oil industry, upgrading existing manufacturing plants to olive oil biorefineries and therefore supporting the circularity in this key sector in t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'A sophisticated multi-parametric system for the continuous-effective assessment and monitoring of motor status in parkinson's disease and other neurodegenerative diseases' (PERFORM), addressing dissemination and exploitation.

assistant: **Impact**

The PERFORM project aims to tackle problems associated with the efficient remote health status monitoring, the qualitative and quantitative assessment and the treatment personalisation for people suffering from neurodegenerative diseases and movement disorders, such as Parkinson's disease (PD). The PERFORM project aspires to research and develop an innovative, intelligent system for monitoring neurodegenerative disease evolution through the employment of a wide range of wearable micro-sensors, advanced knowledge processing and fusion algorithms. Advanced sensors, attached to everyday personal gadgets (e.g. cloths, accessories) will be able to 'sense' the user's behaviour and motor status and store the recorded data in a local portable/handheld computer. These data are then processed and seamlessly transmitted to the centralised system for further fusion, monitoring and evaluation. The system will be modular and extensible, to enable different combinations of measurements. An indicative list of measurements includes: tremor through accelerometers or gyroscopes and possibly ElectroMyoGram (EMG), skin conductivity and sweating through appropriate Galvanic Skin Response (GSR) sensors, SPO2 and pulse rate through a pulse oximeter sensor, bradykinesia, through the finger tapping, other similar tests using devices to detect finger pressure such as piezo-electric and eye blinking rate through ElectroOculoGram (EOG) measurements. All monitoring gadgets will be wirelessly connected and seamlessly integrated to produce a user-friendly and patient-customised monitoring tool. The recorded signals will be pre-processed and stored at the patient site. At the point of care (hospital centre), the supervisor health professionals will be able to remotely monitor their patients, personalis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Formally based object oriented development environments' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Research objectives and content Objectives: a i)establish the technical basis of collaboration in regards to the development of an object oriented development environment based on formal underpinnings. ii)establish technical details of the formalisms involved and begin to develop the formal relationships between them. b) The proposed VF has asked to use our previous work on formal methods in the building of an environment intended for real industrial use. This is an important step forward for us in the industrialisation of our work. A significant portion of software engineering activities consist of the construction of real time systems, which have widespread industrial application. The advent of object oriented methods opened up new possibilities for the development of high quality software systems. Currently available object oriented methods fail to adequately reflect the nature of real time systems. Moreover, they lack a formal base - a fundamental feature in safe, modern software development methods. They do not go beyond helping, often in a very efficient way, with the development and understanding of methodologies do not provide the appropriate mechanisms to make inferences about the behaviour of the system under development, or to enable the user to prove the validity of certain assertions or the invariance of particular properties.  Constructing a development system with appropriate inference and proof facilities is a fundamental step in the evolution from craftsmanship to software engineering. Our main goal is the definition of a new methodology, as well as a prototype of its support system, for the development of concurrent real time systems based on (and normally hiding from the users' view) a formal level which provides software engineers with better control
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Medical and social risk factors and magnitude of first and second trimester obstetrical complications (abortion,miscarriages,ectopic pregnancy) in six developing West African countries' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

The general objective is to deploy an African network for research and analysis of human reproduction and maternal health in six West African countries.The specific objectives are to:* Assess the magnitude of abortion complications in several maternities of the following six West African countries: Benin, Burkina Faso, Cameroon, Ivory Coast, Guinea and Senegal.* Describe the type of abortion complications and the health consequences in terms of maternal morbidity and mortality.* Identify specific determinants of women seeking care for abortion complications.Project methodologyThe methodology will include a descriptive (demo-epidemiological) survey with a complementary qualitative (sociological) approach.Expected OutcomeAt the end of this project we expect to know the incidence of first trimester obstetrical complications (abortion, miscarriage, ectopic pregnancy), and be able to describe the main causes of abortion complications for women admitted to maternities in different sites in the six African countries. The project will give a better understanding of the reproductive knowledge, attitudes and behaviour of women in several sites (urban and rural) of West and Central Africa. EU-African networking will be further developed and will be made available in the field.Point 1: - reception of the administrative and scientist agreement to participate - reception of the names of the coordinators and of the field workers - obtention of a first version of the registerPoint 2: - results of the pre-test; obtention and print of the final version of the register - obtention of a brief description of each site (medical and para medical personnel, number of admissions, number of births per year, etc.)Point 3: - obtention of a first data set after two months of data collectionPoint 4:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Twinning for excellence in biophysics of protein interactions and self-assembly' (TWIN2PIPSA) under Horizon Europe.

assistant: **Objectives**

TWIN2PIPSA will improve R&I capacities of FC.ID/ULisboa (Portugal) in the field of protein folding biophysics and conformational diseases by partnering in joint Twinning activities with three world-leading research and technological development performers: the University of Cambridge (UCAM), the University of Copenhagen (UCPH), and Tel Aviv University (TAU). The folding and misfolding of proteins, their interactions and self-assembly in cells is central to biology and has implications in diseases that affect millions of people worldwide. The so-called conformational diseases include cataracts, metabolic disorders and neurodegenerative pathologies such as Alzheimer’s Disease. Knowledge on the ability to modulate protein interactions and self-assembly is critical to develop applications of protein-based biomaterials like bioadhesive glues or to design therapeutic antibody biologics. TWIN2PIPSA fulfils local needs and will generate outstanding contributions through investigations of pathological self-assembly in vitro and in living cells, nanoscale characterization of protein-based materials and implementation of integrative biomolecular simulations that will raise the international profile and scientific standing of FC.ID/ULisboa. This will enable a local cluster of excellence whose scientific and technological breakthroughs will empower both project partners and the industry sector in their regional innovation ecosystems. The partnership and network will significantly reinforce the R&I capabilities of the widening institution and Portugal’s innovation performance. TWIN2PIPSA comprises several Twinning activities: staff exchanges, secondments to partners, expert visits, meetings, training schools and a joint exploratory project that will translate into biomedical and biot
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Open ContEnt Aware Networks' in the context of a Seventh Framework call.

assistant: **Objectives**

OCEAN will design a new open content delivery framework that optimizes the overall quality of experience to end-users by caching content closer to the user than traditional CDNs do and by deploying network-controlled, scalable and adaptive content delivery techniques. The OCEAN architecture will clearly define light-weight signalling protocols and public interfaces between its major building blocks (Request routing", "Server selection", "Content population and delivery", "Content storage and caching", "Content, user, network and end-devices context description and signaling", "Content, user, network and end-devices context awareness and adaptation") in order to foster multi-vendor solutions and contribute to cut down content delivery cost. OCEAN will elaborate business strategies providing better investment incentives to the different types of players in the value chain (content providers, Internet service providers, CDN service providers and industrials). OCEAN will build innovative self-learning caching algorithms that meet the specifics of the highly unpredictable location and time-dependent consumption patterns and dynamically adapt to the rising popularity of future delivery services. New media-aware congestion control mechanisms based on slight, but controlled quality degradation will provide a better alternative than mere blocking of user requests. The validity and performance of these algorithms and mechanisms will be assessed through simulations, large-scale emulations and a trial in a real ISP network.To reach these objectives OCEAN combines complementary business and technical expert partners representing the whole online multimedia content delivery chain.The OCEAN partners are committed to leverage their strong position in standardization and influence on th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'MINAPATH: A novel and unique method to diagnose and prevent diseases that are caused by exposure and accumulation of inorganic mineral dusts.' (MINAPATH).

assistant: **Innovation**

Today healthcare faces critical challenges coming from an ageing population and the rise of chronic diseases. With a population expected to reach 9 billion people by 2050, healthcare expenditure is at risk of becoming unsustainable. Sustainability requires diagnostic methods to become more efficient, fast and accurate, to facilitate the use of adequate therapy. Despite the effort being made, there are still many diseases that get categorized as idiopathic (unknown cause). Specially in the lung, many inflammatory conditions fall under idiopathic category and stay undiagnosed, while slowly progressing, deteriorating the patient’s quality of life. However, many idiopathic conditions do have a common factor: exposure to mineral dusts such as asbestos, silica or metals (nickel, cadmium & cobalt). We are all at risk of exposure to these minerals, from the environment and workplace, being an occupational hazard in industrial settings and construction sites. Importantly, many of these mineral dusts are carcinogenic, contributing to the increasing prevalence of cancer globally. Despite their impact, today there are no dedicated diagnostic tests to assess mineral exposure, and diagnosis is mostly based on exclusion. In response, we at Minapath have developed a unique method that combines qualitative & quantitative analysis to diagnose the patient’s mineral exposome, serving to identify the underlying cause behind many cases of inflammatory & cancer conditions. After demonstrating the diagnostic relationship between mineral deposits and idiopathic pulmonary diseases, our goal with this project is to finalise the development of our technology and reach market maturity. To achieve these goals, in Phase 1 we aim to carry a Feasibility Study that help us prepare for the main technical
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Advance Challenging Statistical Analysis for Massive High-Dimensional Nonlinear Spatial Time Series' under Seventh Framework.

assistant: **Concept**

Modern society, including Europe, faces a variety of global issues, such as global environmental (including climate) changes, global economic and financial crises as well as global energy and sustainable development. Many of these global challenges facing humanity are geo-spatial in nature, with big spatio-temporal data from location-based events or services that are complexly connected and interdependent, requiring advanced, more accurate and effective statistical and econometric techniques in modeling and forecasting of various risks associated with these global challenges.This project aims to develop the cutting-edge methodologies to advance the challenging theoretical and practical issues in statistical inference and econometric analysis of massive high-dimensional nonlinear spatial time series. It will explore some fundamental and difficult issues and establish a unifying novel theory for a framework of non-parametric and semi-parametric approaches to modeling and forecasting of massive nonlinear spatial time series data that involve complex structures and information both from temporal and spatial dimensions arising in such important applications as predicting environmental and climate as well as socioeconomic risks. The developed new generation of statistical and econometric technologies will empower the practitioners and policy-makers to produce more accurate quantitative forecasts that help to generate more informed countermeasures with regard to various risks that our modern society faces.As one of the international pioneering researchers in nonlinear spatial and spatio-temporal data analysis, a new subject in the discipline of Statistics, this project, if supported, will greatly enhance and integrate the principal investigator (PI)’s research and career into