RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Euro-Workshop on Mathematical Views on Architecture, Art and Design'.

assistant: **Objectives**

The MatOmium 2001 is an Euro-Workshop on Mathematical Views on Architecture, Art and Design. It will welcome mathematical ideas inspired by remarkable observations or sensory perceptions and vice versa real and virtual forms" with an original mathematical interpretation. Topics are locations or objects of interest to wandering mathematicians, structure of design objects or (musical) compositions, mathematical views on architectural achievements, artist's interpretations. The contributions selected for MatOmium 2001 will be thematically linked to exceptional locations: the Atomium (Belgium's nine-sphere landmark), an Institute for non-European Art and Sciences (Belgium's history is linked to Africa), and the Horta Drawing Museum (built by the Belgian architect). Participants will experience the impact of adapted locations for acquiring a genuine inspiration. MatOmium 2001 is a regional conference of Nobel Prize Yuval Ne'eman's ISIS.It will encourage an interaction between remote disciplines. Society sometimes seems subdivided in two worlds, with the artistic world on one side, and the scientific at the other. Competition will force them to work towards a mutual understanding, as this subdivision affects the quality of life. Organisations based in the US, Argentina and Australia have similar objectives. However, senior researchers in Europe start to realise that their continent should not stay behind in this worldly movement. Editors of leading mathematics journals paying attention to MatOmium like topics will join forces: The Mathematical Intelligencer, the Eur. Math Soc. Newsletter, the Nexus Journal, Visual Mathematics (electronic journal). Moreover, special "Women in Science" sessions will stress that women scientists play a leading role in this mathematical field.ftp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Meeting of Energy Professional Skills'.

assistant: **Concept**

MENS is a project conceived in order to provide an enhance the NZEB skills of building managers such as engineers and architect through a series of accredited training activities developed by 9 universities and 3 market players. MENS aims: - To increase the knowledre and skills of at least 1800 building managers (engineers, architects) in NZEB design and construction, out of which 50% would be women or unemployed. - To create and implement a new education and training program for such professionals in 10 countries, under the European Qualifications Framework provisions and based on desired and common learning outcomes of Level 7.- To create and implement an innovative, interdisciplinary education and training program with an integrated approach, focusing on real case studies - To accredit courses using the formal procedure in each country and assign ECTS credits.- To enhance and support the development of a professional network in Europe specifically focused on retrofitting of housing stocks towards NZEB. A connection with over 250,000 stakeholders and market players.- To provide working opportunities to unemployed professionals, by bringing them closer to possible employers and improving their qualifications, at a percentage of 30% of those attending.- To continue the education and training courses for at least 5 years after the end of the project based on concrete sustainability plans agreed by University partners.- To result in energy savings and/or increased use of renewables of at least 28,96 GWh/year.MENS is developed through 3 sets of training activities: national accreditation professional courses; e- learning and webinars: and case studies experiences around Europe and it involves involves major universities and stakeholders either directly or as Associated Par
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Realignment: ENHANCING IMPLANT PERFORMANCE THROUGH STRUCTURAL REARRANGEMENTS IN HYDROXYAPATITE'.

assistant: **Innovation**

Hydroxyapatite is used extensively in orthopaedic implants, and has benefited from the known biocompatibility of apatites within teeth and bone. Continual material development is hindered from several factors. One of these is the unknown influence of structural modifications on the properties. The variability of properties is, in part, attributed to the flexibility to permit atom vacancies and accommodate lower hydroxyl contents. This project will assess the impact of dehydroxylation on material properties (mechanical properties, solubility, charge) and cell response. The range of solid solutions from hydroxyapatite to oxyapatite will be studied to show the effect on the properties. Dehydroxylated hydroxyapatite will be studied and the most suitable technique (X-ray diffraction, nuclear magnetic resonance, microRaman spectroscopy, Fourier transform infra red spectroscopy or luminescence) applied as a new quality control technique. This will pave the way for also developing hydroxyapatite as a new heat sensor. The concentration of remaining hydroxyl ions and the positioning will be an indicator of the heat environment and the mixing within the droplet at high temperatures. Attention will be directed to hydroxyl ions in the structure to provide a charged surface. The hydroxyl ions will be oriented to impart a surface charge. A new technique will be generated for providing new in-situ charge generation during coating formation with thermal spraying. This project will introduce a new quality control technique for measuring hydroxyl content and orientation, introduce a new tool for monitoring the high temperature environments and fnally produce a new approach for imparting a charge on coating surfaces.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Identification of Host Determinants for Virus Entry using a Haploid Genetic Approach'.

assistant: **Objectives**

The most powerful and direct way to get insight into complex biological systems is to remove individual components and observe the consequences. Cultured human cells are widely used to model and study aspects of human disease. Although human cells can be analyzed and manipulated in numerous ways, their genome has remained refractory to efficient mutagenesis-based analysis.We have developed an insertional mutagenesis-based approach in haploid and near-haploid human cells.  We have shown that this approach enables the generation of null alleles for most human genes and can be used to pinpoint genes that are involved in phenotypes of interest. We have made use of parallel sequencing approaches to generate high-density genetic overviews of genes that are required for phenotypic cell states. In a variety of genetic screens we have identified host factors required for infection of cells by influenza virus, the first entry receptor for a Clostridium Difficile toxin and a set of host factors that play a role in the entry of Ebola virus. Importantly, we can carry out and analyze a genetic screen in a period of weeks in a cost-effective manner.This application outlines experiments aimed at identification and detailed characterization of host factors that play a role in Filovirus infection. Moreover, we propose a number of experiments to gain mechanistic insight in the role of the Niemann-Pick C1 cholesterol transporter in entry, tropism and the fusion process of Ebola virus. Furthermore we propose to develop refinements in our screening approach. Finally, we will apply our haploid screening platform to generate a “Host Factors Atlas’ for 50 diverse viruses that infect the human population. We foresee that the outlined experiments will provide an detailed and accurate overview of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Unravelling the impact of vortex-induced vibrations for enhanced wind turbine safety' (VIV-WISE), addressing dissemination and exploitation.

assistant: **Impact**

Despite significant advancements in offshore wind turbines (OWTs), effective life cycle assessment remains a critical challenge. An emerging limiting factor in the lifespan of these structures is vortex-induced vibrations (VIV), which may occur during the installation process, before the towers are commissioned in offshore wind farms. Over several weeks, VIV can cause substantial oscillation amplitudes, potentially leading to significant fatigue damage before the OWTs are fully operational. This issue is becoming increasingly crucial as OWTs grow in size and reduce in weight. In this context, the VIV-WISE project aims to develop and verify a new multi-physics numerical framework to address this issue. This tool seeks to (1) surpass the accuracy of current state-of-the-art by integrating novel fluid-structure interaction methodologies with recent advancements in damage mechanics, specifically the Phase Field model for fracture, to provide insights into fatigue damage caused by VIV in metals - particularly cylindrical shells and welds. (2) Establish a guide for identifying cracks induced by VIV in pioneering wind tunnel experiments, and (3) assist in the OWT tower installation process, thereby preventing significant failures before operation. Hence, VIV-WISE addresses a complex, multi-disciplinary phenomenon that encompasses both solid and fluid mechanics. The proposed methodology will not only be valid for OWTs, but also for other industrial sectors where VIV-induced fatigue damage is a concern, such as chimneys, marine risers and bridges.


**Keywords:** Fracture Mechanics, Vortex-induced vibrations, Phase Field, Fluid-structure interaction
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'DevelOpmeNt of Cancer RNA TherapEutics' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Non-codingRNAs (ncRNAs) represent a large class of molecules that in concert regulate the expression of genes involved in the key pathways governing cancer development and progression. They represent ideal targets for personalized cancer therapies and if appropriately designed they can provide specific, non-toxic and effective therapeutic tools. The identification of novel therapeutic ncRNAs and the design of their appropriate formulation is a key aspect for their clinical applicability. RISE- cONCReTE aims to form an international and inter-sectoral network of organizations working on a joint research programme on the development of a safe ncRNA-based drug. RISE- cONCReTE teams up experts in the fields of Molecular Oncology, Epigenetics, Signal transduction, Animal models, Therapeutic delivery and Imaging, business, and education. The participants will exchange skills, knowledge and staff members that will be exposed to synergetic and complementary research environments. RISE- cONCReTE will undertake an integrated approach to reveal novels functional links between ncRNAs and oncogenic pathways. We will: a) characterize novel classes of tumor-associated ncRNAs; b) investigate the impact of ncRNAs on key aspects of tumor cell biology; c) develop cargoes (e.g. aptamers) for delivering therapeutic ncRNA derivatives into specific cancer cell types. By using innovative in vivo imaging tools, we will monitor the accumulation of target ncRNAs in cancer cells and evaluate their biological efficacy in inhibiting the growth and spreading of malignant tumors. The resulting approaches will provide stable and effective tools thus potentially improving the quality of life (QOL) of the cancer patients. Further, the joint research and training programme of RISE- cONCReTE will be perfor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Plasma Etching for desired nano-Feature shape and nano-texture: An Advanced Reactor and Simulation Software for Feedback-Loop Plasma Control' (NANOPLASMA), addressing dissemination and exploitation.

assistant: **Impact**

We propose a step change in the way plasma etching processes are controlled, through understanding, measuring and controlling the key parameters determining the environment experienced by a processed substrate. We will use simulation, experiments and innovative plasma processing concepts to demonstrate robust PLASMA ETCHING OF NANO-SCALE FEATURES as well as CONTROLLED SURFACE NANO-ROUGHNESS and texture. We will use a multi-level nested approach for the understanding and optimisation of plasma processing for nanotechnology: The first level is the plasma tool and the gas phase plasma state, the second level is the surface and the features being etched, while the third level is the nano-texture and nano-roughness of the surfaces and features etched. A feedback loop will be developed to optimise simultaneously all levels of the nano-scale etching This will greatly improve the ability, especially of SMEs, to achieve reliable fabrication of nano-devices in small batch development, and in the scale-up to larger production quantities.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Nice Environment with a Process and Tools Using Norms (UML, XML and XMI) and Examples'.

assistant: **Objectives**

The problems for analysts are:(1) How to use UML notation for analysis and design reusable components in specific domains?(2) How to be sure that the analysis is complete and consistent?(3) How to check the pertinence of the analysis with a specialist who is not comfortable with UML?(4) How to describe reusable components?Our main objective is to solve these problems by providing:(1) a process using the UML notation in three contexts (software, business processes and knowledge engineering);(2) plug-in tools that can check UML diagrams and that can generate different types of documentation in different contexts. These tools will be complementary to existing UML tools and will be usable from Internet. We achieved these objectives with a group of partners, specialist in each theme. The results of this project will be used by an increasing number of UML users in the world.Objectives:The different objectives of the project are:(1) Definition of the process which can be a guideline in different activities (software, business processes and knowledge engineering). This process guide (a book) is a common base for UML users;(2) Definition of one tool that can check the coherence of different UML diagrams according to the context in which the notation is used;(3) Definition of one tool that can generate documentation in different contexts. This tool must provide different points of view on the analysis and design phases, according to the reader of the documentation and his knowledge of UML notation;(4) All of the tools developed in the project must be usable from Internet without specific editing tools. The process guideline (the book) and the tools must make the use of UML notation easier and, will promote this use into several contexts.Work description:The work is organised arou
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Understanding horse speciation and domestication through comparative palaeogenomics' (HORSEDOMESTICATION) targeting Seventh Framework.

assistant: **Abstract**

Horses have played a critical role in human societies, warfare and for facilitating the exploration of novel territories. In addition, the rich fossil record of the horse family over the past 55 million years has made it an icon for the patterns and processes of macroevolution. However, most horses have become extinct in the wild precluding direct comparison of domestic and wild horse genomes to understand the processes of domestication and speciation. Here, I propose to use state-of-the-art ancient DNA methods in combination with 2nd and 3rd generation sequencing technologies to characterize the complete genomes of the modern donkey, the Przewalski's horse and of two Pleistocene horses, dating back to more than 12,000 years ago. Through comparative genomics, these genomes will deliver the sequence of all horse genes before humans started breed selection and will identify the genetic changes that occurred in the course of the domestication process. In addition, direct comparison between the genomes of the Przewalski's horse and those of pre-domestic Pleistocene horses will clarify the conservation status of this highly endangered horse. While promising to supersede 2nd generation approaches, no 3rd generation sequencing technology has been so far used in ancient DNA context. This project is the first exploring the potential of 3rd generation approaches for ancient DNA, which could open access to a whole range of fossils previously considered as devoid of any trace of DNA. At the genetic level, the domestication process has never previously been studied through the merger of ancient and modern genome-wide data. Therefore, this project represents an unprecedented attempt to understand the dynamics of genomic changes over time in relation with animal domestication.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Intelligent systems for autonomous wind power plant operations' to be submitted under Horizon Europe.

assistant: **Abstract**

The IntelliWind Doctoral Network will train the next generation of multidisciplinary researchers who will develop intelligent systems that support autonomous wind power plant (WPP) operations. A team of 16 Doctoral Candidates supported by academic and industrial partners will collaboratively pursue the primary research objective of reducing the role of humans in the decision process, as well as reducing the need for direct human interventions in the operations and maintenance process. This frees up human resources to carry out more elaborate, better planned, and more efficient operations leading to significant improvement in cost efficiency and increased feasibility of wind farm operations. The project will trigger a change in thinking in the skills and tasks that are being used in WPP operations from classical engineering tasks to designing, analysing, and interacting with automatic machine algorithms.IntelliWind aims for maximum impact by training professionals that have the skills to drive transformational change in their organisations, by driving the implementation of novel solutions and efficiently transferring new skills to their colleagues. This is ensured through delivering world-class training focused on ""train the future trainers"" concept where each researcher's impact goes beyond the product of a single person's efforts, as well as providing skills that define the next generation of technical leaders who can deliver transformational changes.""


**Keywords:** Decision modeling, autonomous operations
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Cardiac myosin light chain kinase function in human pluripotent stem cell derived cardiomyocytes'.

assistant: **Concept**

The main hurdle to the effective use of stem cell derived cardiomyocytes (hESC-CMs and hIPSC-CMs) in drug toxicology screening and transplantation therapy is their embryonic nature. It is recognised that hESC-CM and hIPSC-CM are immature and undergo limited maturation in the laboratory. This creates problems as the cells may not display appropriate responses to target drugs in toxicology screening and may not be suitable for transplantation into the damaged heart. The research outlined in this proposal will begin to address these issues.The aim of my proposal is to study the function and regulation of the recently discovered cardiac myosin light chain kinase (MLCK) and its downstream targets, regulatory myosin light chain (MLC) proteins. Evidence suggests that cardiac MLCK is responsible for modulating cardiomyocyte contractility. In studying the function of cardiac MLCK I aim to generate hESC-CM and hIPSC-CM with an increased structural maturity, which will be more suitable for drug toxicology screening.Importantly, the study of cardiac MLCK also has clinical relevance. Expression of cardiac MLCK is downregulated in the hearts of rats that suffered induced myocardial infarction, and when used to treat these animals, upregulation of the gene can improve cardiac output. Investigation of cardiac MLCK function in human cardiomyocytes in this proposal may provide insights into a potential role for cardiac MLCK in the treatment of heart attack patients.Finally, the proposed research will also highlight the potential of hESC-CM and hIPSC-CM as models to study the basic biology of the human heart.