RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Predicting the future: How our brain predicts future events for successful navigation through our dynamic environment.'.

assistant: **Concept**

To successfully navigate our dynamic environment, our brain needs to continuously update its representation of external information. This poses a fundamental problem: how does the brain cope with a stream of dynamic input? It takes time to transmit and process information along the hierarchy of the visual system. Our capacity to interact with dynamic stimuli in a timely manner (e.g., catch a ball) suggests that our brain generates predictions of unfolding dynamics. While predictive processing theories assume an internal representation of future external states, empirical research typically employs neural measures that capture an indirect consequence of prediction. The representational nature of predictions remains largely unexplored. One approach for investigating neural representations is representational similarity analysis (RSA), which typically uses models of static stimulus features at different hierarchical levels of complexity (e.g., color, shape, category, concept) to investigate how these features are represented in the brain. I have recently developed a novel dynamic extension to RSA that uses temporally variable models to capture neural representations of dynamic stimuli. A proof-of-concept MEG study unveiled predictive neural representations of naturalistic dynamic input. These promising initial results open the door for addressing important outstanding questions on how our brain represents and predicts the dynamics of the world. In this project I aim to answer these questions. I will execute the project at the prestigious Donders Institute in the lab of Floris de Lange, a leading expert in the field of predictive processing. The proposed project is unique as it tackles the rich dynamics of predictive processing in terms of neural representations. It will al
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'PN6047 - a breakthrough treatment of neuropathic pain' under Horizon Europe.

assistant: **Concept**

PharmNovo aims to develop novel drugs with superior clinical properties to treat patients suffering from chronic pain using knowledge and experience in drug design and G protein-coupled receptor pharmacology.Pharmnovos lead drug candidate is PN6047 - a completely new type of opioid drug for neuropathic pain, with a first-in-class market potential. Unlike the currently available opioid drugs which activate all opioid receptors, PN6047 is a very selective delta opioid receptor agonist (activator). Due to its unique molecular structure, PN6047 selectively activates the G protein signalling pathway while avoiding those leading to unwanted side effects such as the arrestin protein signalling pathway that mediates receptor desensitization and analgesic tolerance and possibly proconvulsant activity. PN6047 can be the first of a new drug class for neuropathic pain treatment - delta opioid-biased receptor agonists (DOBRAs). Preclinical studies have shown that PN6047 is safe, tolerable and effective in treating neuropathic pain and also other pain-related indications such as opioid withdrawal and chronic cough. The clinical Phase I study has confirmed that PN6047 is safe and tolerable at doses predicted to be efficacious.Now the drug is ready to proceed into a Phase IIa PoC study, which is the focus of the proposed Accelerator project. The confirmation of the clinical efficacy of PN6047 will enable us to enter an out-licensing agreement with one of the major players in the chronic pain market. Alternatively, it would allow us to attract significant equity investments and finance subsequent Phase IIb and III clinical trials, scale up manufacturing, market approval and product launch.This project is of strategic health-economic importance for Europe. About 149 million people in Eur
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Numerical Investigation of Two-Phase flows for ORC applications' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

With this proposal I aim to develop an accurate and robust numerical tool for the simulation of compressible two-phase flows for Organic Rankine Cycle (ORC) applications. Recent studies have shown that the power output of ORC systems may be increased up to 30% by implementing a wet-to-dry turbine expansion, which starts in the two-phase regime and ends in the dry vapor. Advanced numerical tools are required to confirm these predictions, and to investigate more accurately these flows. To ensure an adequate level of reliability, I propose to develop a numerical tool based on the non-equilibrium Baer and Nunziato (BN)-type model. The suggested model naturally takes into account non-instantaneous mass and heat transfer. By using an adaptive strategy based on non-standard criteria to predict the local flow topology, the model will also be able to deal with the different flow topologies that occur in a wet-to-dry expansion. Finally, the effects of the finite relaxation scales will be investigated through a parametric study, and specific empirical indications for two-phase ORC systems will be delivered to the community involved in their optimization and design.The developed simulation software will be released under an open-source policy within the SU2 simulation toolkit, a choice that will help engineers solve transient two-phase fluid dynamics problems. The ensuing availability of an adaptive diffuse interface method will also contribute to answer the need for advanced numerical methods able to effectively deal with the multiscale nature of two-phase flows.The inter-disciplinary character of the NI2PhORC project, which blends techniques of fluid dynamics, applied mathematics, and scientific computing, represents an invaluable opportunity for me to develop a solid and compreh
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'The role of layer-specific population receptive field properties in visual recurrent processing' (FFvsFB-UHF-fMRI).

assistant: **Innovation**

Visual perception has long been cast as an inference process, in which feedforward sensory signals are integrated with expectation-related feedback. For every feedforward sensory pathway, there is a reciprocal feedback projection, yet standard models continue to represent vision as a feedforward hierarchical network. Such models fail, however, when confronted with cases in which global spatial context, expectations, or other higher-order cognitive functions affect local processing. The characterization of the distinct roles and mechanisms of feedforward and feedback processing is thus crucial for better models of vision. Based on the theory of predictive coding, a proposed implementation of visual inference, we propose the receptive field (RF) as the mechanism by which feedforward and feedback processes interact. We present three projects that harness recent advances in neuroimaging techniques, allowing in vivo imaging of recurrent processing in humans. Ultra-high field (UHF) functional magnetic resonance imaging (fMRI) enables a hitherto impossible investigation of layer-specific cortical processing, with different cortical layers receiving input from either feedforward or feedback channels. We will leverage the sub-millimeter spatial resolution of UHF fMRI, together with population receptive field (pRF) mapping, to target feedforward and feedback RF properties in two behavioral paradigms - visual crowding and Mooney image disambiguation. Crowding is dependent on global spatial context, recruiting recurrent processing between early and mid-level visual areas, whereas the prior object knowledge manipulation involved in Mooney image disambiguation targets early to high visual areas. The investigation of the contextual modulation of layer-specific pRF properties will help
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Malopolska Researchers’ Night 2011' in the context of a Seventh Framework call.

assistant: **Objectives**

Malopolska Researchers’ Night 2011, an event hosted by the region’s four cities and towns: Krakow, Tarnow, Nowy Sacz and Niepolomice. On this special Night you will be able to feel like Harry Potter on a journey to meet incredible researchers. On 23 September 2011 Malopolska will go science mad for the fifth year running! The fifth anniversary of Malopolska Researchers’ Night will not be the only reason to celebrate. The year 2011 will also mark the 500th anniversary of the arrival of the first guinea pig in Europe and the 100th anniversary of Marie Curie’s Nobel Prize in chemistry. This will be the only night of the year when researchers will turn into excellent actors, directors, musicians, guides to the nooks and crannies of research laboratories, contestants and, above all, incredibly fascinating individuals. Attractions will range from experiments with public participation through innovative demonstrations, experiments, do-it yourself workshops to fascinating discussions, shows, concerts and games. Everybody will find something interesting for themselves. The project attracts huge public interest in the region and beyond (ca. 3,500 participants in 2007, ca.15,000 in 2008, ca. 20,000 in 2009 and ca. 27,000 in 2010). Factors such as the experience of previous years of the project and effective and well-established partnerships within the region are helpful in preparing the event and making it get better and better, year by year. A total of 13 Partners and 22 other organisations will participate in the project As many as approx. 520 researchers will be running activities on the Night with the help of over 240 students. The event will take place in 33 locations throughout Malopolska. The programme of attractions will include 71 workshops, over 150 shows and demonstrati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Exploring Low-valent Pnictogen Species towards Asymmetric Redox Catalysis', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The European chemical industry is a global leader, generating over €655 billion in annual sales and 12% of manufacturing employment. Catalysis underpins most chemical manufacturing, yet current processes still rely heavily on scarce, expensive, and geopolitically sensitive transition metals (TMs), such as rhodium, palladium or iridium. To ensure resource independence and achieve Horizon Europe’s strategic objectives, there is an urgent need for sustainable, cost-effective catalytic alternatives.PICNIC, led by Dr Irene Sánchez Sordo (ISS), addresses this challenge by pioneering the use of low-valent pnictogen (Pn) species, focusing on Sb and Bi, as earth-abundant and inexpensive catalysts for carbon–fluoride bond activation and formation of new bonds. In addition, enantioselective redox transformations remain virtually inaccessible to main-group (MG) elements, leaving a critical knowledge gap. PICNIC will address this challenge by exploring the reactivity and mechanistic landscape of Pn(I)/Pn(III) redox processes, unlocking first-in-class catalytic methodologies based on readily available elements and tackling current issues related to persistence and bioaccumulation of organofluorine compounds in the environment. The project integrates rational ligand design, mechanistic studies, and catalytic development through a bottom-up strategy: from stoichiometric investigations to racemic catalysis, culminating in enantioselective applications. PICNIC’s multidisciplinary approach bridges hardcore inorganic and organic methodologies, and leverages OP’s EU-wide collaboration network, including experts in computational chemistry and spectroscopy. By replacing scarce TMs with abundant MG elements, PICNIC aligns with the EU Green Deal 2050, the Horizon Europe Sustainable Development
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'B.E.N.E.I2 2017-2018 - BENE Innovation Internationalisation services 2017-2018' under Horizon 2020.

assistant: **Concept**

The project aims at offering specific innovation services to 2 different groups of SMEs based in the Brussels Capital Region: the SME Instrument beneficiaries on the one side, and the SMEs having a high potential for growth and internationalisation by the enhancement of their innovation management capacity on the other side.These services will be an integral part of the Enterprise Europe Brussels services. Although for the SME Instrument beneficiaries the proposer depends on the number of successful SME granted and notified by EASME, a funnel approach will be adopted for both groups of SMEs in order to have an upstream estimation and selection of the SME potential existing in the region.This funnel and selective approach will also take into consideration the permeable frontiers which divide one SME group from the other, in the light of the innovation needs and capacities existing at a given time of the SME lifecycle.The service provision for Group 2 will be ensured via a structure process, relying on a contest approach, SME pre-selection, set-up according to a predefined methodology, which relies on ad-hoc tools (and based on 9 criteria) and methodologies, designed with the aim to select only those SMEs with capacity, clear intent and ambition to benefit from the innovation management assessment. In function of the score obtained in the different criteria, the SME will be selected (or not) to benefit from the innovation management capacity assessment held with one of two retained tools, both complaint to EU standard CEN/TS 16555-1 “Innovation management system”.The BENEI2 2017-2018 proposal addresses the obstacles which hinder SME from being more competitive, from growing and creating jobs, thus having a real impact in the regional economy.


**Keywords:** SME, innovati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Scalable Optimization of Power Systems with  Flexible Demand and Renewable Supply' to be submitted under Horizon 2020.

assistant: **Abstract**

The large-scale integration of renewable resources in electric power systems requires the mobilization of flexible consumers who can adapt their consumption to the variable and uncertain fluctuation of renewable supply. The mobilization of demand-side flexibility remains an elusive goal in electric power systems, while the majority of flexible consumers are connected to distribution systems that are currently operated passively. The major obstacles towards the optimal management of demand-side flexibility include the enormous number of flexible consumers (with ensuing challenges for scalable optimization), the presence of uncertainty at all layers of the power grid, and the physical complexity of distribution system power flow. In this context, the ICEBERG project proposes a novel approach towards the proactive utilization of transmission and distribution system resources in a coordinated fashion.My approach to achieving this ambitious goal is based on three key ingredients. (i) The first ingredient is a novel approach for planning and simulating the dispatch of the system which exploits the structure of distribution networks and can scale to systems of arbitrary size. (ii) The second ingredient is an original optimization framework for tackling uncertainty and non-convexity at every layer of the system. (iii) The third ingredient is a novel implementation of this optimization framework in parallel and distributed computing infrastructure, which will enable the optimal short-term planning and real-time coordination of resources at all layers of the system. My vision is to break down the current barriers to renewable energy integration by mobilizing the as yet untapped flexibility that is present at all layers of the network. This will enable the achieving of ambitious s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Safeguarding Migratory Fish and their Habitats in the Danube River Basin and beyond' in the context of a Horizon Europe call.

assistant: **Objectives**

DANUBE_lifelines supports the objective of the Mission ‘Restore our Ocean and Waters’ to protect and restore marine and freshwater ecosystems and biodiversity. The key components of the project include knowledge creation, demonstrating effective solutions, as well as co-creation with stakeholders. The project generates new insights and perspectives on fish migration, habitat quality, and migration corridors improving the status of migratory fish species in the Danube River Basin. It demonstrates measures for protecting and restoring habitat availability, accessibility, and connectivity by removing barriers and pressures and implementing nature-based solutions. Engaging with local actors and national stakeholder groups, conducting training and communication activities, and developing an action plan and roadmap for the replication and scale-up of solutions are also integral parts.DANUBE_lifelines is based on a transboundary, multi-scale and -actor approach that covers several relevant migratory fish species. A basin-wide approach highlights the restoration and conservation needs of migratory fish and their habitats across the Danube River Basin. Furthermore, the project provides a portfolio of solutions for different river sections, including tributaries of the Danube, tailored to local needs and conditions covering the Upper Danube, the Middle and the Lower Danube/Delta. In these regions, integrated approaches are pursued, demonstration activities are learned from and applied, and the conservation of species such as Danube salmon, Pontic shad and sturgeons is improved. Key outputs include the Danube Fish Migration and Connectivity Atlas, identification of hotspot and strict conservation areas for migratory fish, efficiency of restoration measures, mapping the contributio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Pervasive and UseR Focused BiomeTrics BordEr ProjeCT' in the context of a Horizon 2020 call.

assistant: **Objectives**

The goal of the PROTECT project is an enhanced biometric-based person identification system that works robustly across a range of border crossing types and that has strong user-centric features. The system will be deployed in Automated Border Control (ABC) areas supporting border guards to facilitate smooth and non-intrusive rapid crossing by travellers based on deployment of the next generation of biometric identification detection methods. The ability for the system to efficiently process low-risk travellers, combined with increased levels of accuracy, security and privacy standards and enabling border guards to concentrate resource on higher-risk travellers, are central ambitions of the project.  To achieve these goals, a multi-biometric enrollment and verification system is envisaged, taking into account current and next-generation e-Passport chips, mobile equipment and person identification ‘on the move’. Research will be undertaken into optimization of currently deployed biometric modalities, application of emerging biometrics (including contactless finger vein, speaker recognition and angthropometrics), multi-modal biometrics and counter-spoofing, for border control scenarios.  An integral part of the project is collection and dissemination of new border-realistic biometric datasets, and systematic evaluation of the developed biometric methods including vulnerability and privacy assessment.  The PROTECT project is strongly user-driven and demonstration of the developed biometric system will be conducted at two different border crossing sites. Finally, the PROTECT project will make contributions to facilitating border crossing of bona-fide non-EU citizens as well as evolving standards in biometric systems.