RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Molecular exploitation of an extremophile mammal' in the context of a Seventh Framework call.

assistant: **Objectives**

The African naked mole-rat (Heterocephalus glaber) is an unusual rodent species that has evolved physiological strategies to adapt to an extreme ecological niche. It is the only poikilothermic mammal (cold-blooded), has an extraordinarily long life span for its small size (in excess of 30 years) and lives in large colonies organized like those of termites (eusocial). We have shown that naked mole-rats lack physiological attributes thought essential and protective for most other animal species. For example, severe tissue acidosis is life threatening as well as painful and yet naked mole-rats completely lack behavioral sensitivity to acid and sensory neurons are not activated by protons in this species. Here we will identify functionally important naked mole-rat gene variants that may account for aspects of the extreme physiology in this species. We have already identified candidate naked mole-rat-genes whose altered function, compared to other mammals, may account for acid insensitivity, lack of pain sensitization and poikilothermy in this species. These gene variants will be functionally characterized by replacing the mouse gene with a naked-mole rat variant using molecular genetic techniques. In addition we will use next generation sequencing to identify further naked mole-rat gene variants. These studies will allow us to learn how evolution selected for functionally significant gene variants that can radically alter normal physiology in the context of a rodent genome.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Hybrid Eco Responsible Optimized European Solution', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Bridging the gap between HPC and IA/ML user communities and HPC Resources is key to unleash Europe’s innovation potential. A lot of effort is done to build the European technologies able to deliver centralised, petascale/exascale HPC & ML. It is equally important to make such resources easily and responsibly consumable.The project is aiming at developing in a 2 years time frame an innovative european software solution allowing industrial and scientific user communities to submit easily complex Simulation and ML workflows to HPC Data Centres and Cloud Infrastructures as well as being able to take informed decisions for selecting the best platform to achieve their goals in time, within budget and with the best energy efficiency.Although the project will be able, in the future,  to provide value creation across multiple industrial sectors, the demonstrator and the initial focus will address workflows of strategic importance in the field of “Renewable Energy” and in “Manufacturing” applications where HPC is involved for the design of more Energy efficient products (for example in the design of energy efficient vehicles). HEROES is supported by Meteosim, UL Renewables, EDF and Dallara which will advise on workflows relevant to such use cases. HEROES major innovations reside in its platform selection decision module and its application of marketplace concepts to HPC. The consortium involves 4  European SMEs which bring HPC to their clients and are facing everyday this market demand. A major SuperComputing Research Centre complements the project with its specific expertise in energy management and resource optimisation. At the end of the project, its outcomes will be commercialised.


**Keywords:** Hybrid platforms, Energy Efficiency
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'SUstainable sports and Physical activity for Equity and Resilience in the Anthropocene' (SUPER) targeting Horizon Europe.

assistant: **Abstract**

SUPER will train 15 doctoral Fellows as transdisciplinary leaders to develop and promote sustainable, equitable physical activity and sports that prioritise both human and planetary health in the face of world finite resources and a changing climate. The network will bring together sports and physical activity industries, organisations and practitioners with leading researchers and experts across fields such as sports & behaviour sciences, human health, education, social science, planetary health, circular economy, environmental sciences and sustainable development to conduct empirical research and cascading skill-building with the following objectives: Objective 1: Establish the theoretical and evidence base as well as a research roadmap on the impact of sports and physical activity on planetary health, resources and climate and, conversely, the impact of climate change on sports and physical activity. This, to support policy, practice and novel solutions. Objective 2: Develop novel solutions for sports and physical activity policy, infrastructures, equipment, practices and promotion that bring co-benefits by simultaneously increasing population resilience to climate change equitably and lowering the impact on the planet and planetary limits.Objective 3: Test and demonstrate these novel solutions in key sectors through living labs: Health Care, Professional and Amateur Sports, School/Education, Urban Design, Workplace/Occupational Health.Objective 4: Provide evidence-based guidance and scientific support to future generations and all stakeholders who promote, manage, or use sports and physical activity: industry, practitioners, organisations, policymakers, funders, and the public, on making sports and physical activity sustainable and equitable. Objective 5: Build capa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Feasibility Study to Demonstrate Effectiveness and Efficiency of Enamel Remineralisation using Reminova's EAER (Electrically Accelerated Enhanced Remineralisation) Technology for Dental Applications' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Dental caries (tooth decay) is the most common communicable disease, globally affecting 36% of the adult population. It has been identified by the World Health Organisation (WHO) as a major global public health crisis (2008) and costs the European economy an estimated at €60Bn. Reminova is developing technology that ""regrows"" enamel, replacing the need for dental anaesthesia and drilling in the treatment of caries. The novel approach requires the delivery of three formulations to the tooth using a tiny (unperceivable) electric current in a process known as Electrically Accelerated Enhanced  Remineralisation (EAER). This will be used to treat caries in-office without the need for tooth tissue removal.Our development has been welcomed by both end consumers and the dentistry sector and there is a strong market pull to get our technology to market. Patients want a painless solution that maintains and repairs their teeth, so they may retain them throughout their lifetime. Dentists are keen to embrace a shift to preventative and curative dentistry as opposed to the current reparative approach used when drilling and filling teeth. To achieve market success it is anticipated the device should control rapid remineralisation of precavitated lesions within existing timeframes and treatment pathways. This Phase 1 H2020 award would be used to undertake initial feasibility work and planning on how we can optimise remineralisation to a 15 minute time-frame. We believe that this is critical to the commercial viability and scalability of an identified €1.7–4.4Bn global market in the first 3 years of market entry for the device.The core activities of our phase 1 project would be initial feasibility work on techniques for optimisation and building a suitable approach and methodology for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Advanced training in Laser Sciences' under Sixth Framework.

assistant: **Concept**

The main objective of this Early Stage Training project is to provide advanced training on laser-based science and technology to be used on cutting edge multidisciplinary research in bio-physics/chemistry and nanoscience. The training is offered by four leading European Laser Facilities, (IESL-FORTH, Heraklion, Greece; LENS, Florence, Italy; LCVU, Amsterdam, the Netherlands; VU LRC, Vilnius, Lithuania), complementary in their expertise with a long standing history in collaborative research training projects , training of facility users, and coordination of large scale synergies. A total of 20 young researchers will be trained in technological and scientific research frontiers such as: Ultra-fast lasers: advanced coherent radiation sources based on optical parametric generation and low and high-order harmonic generation. Molecular Imaging: novel-imaging techniques for the detailed mapping of chemical processes. Biomolecule dynamics: state-of-the art laser spectroscopic methods and laser optical tools for the manipulation and study of biomolecules at the cellular and molecular level. Nanotechnology: Ultra fast laser methods for dynamic studies of nanostructures and processing of materials at the nano-scale level. The multi-site training will enable young researchers no t only to exploit the technological complementary of the participating EU laser facilities and but also interact directly with talented scientific expertise across the host institutes and Europe since all these facilities host top researchers from the EU and abroad. Overall, the project is expected to endow young researchers with competitive skills, both scientific, stemming from intense research training at a very high level, and managerial from witnessing first hand how large scale facilities operate, thu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Methane paradox revisited: Unravelling the impacts of eutrophication on microbial methane cycling in aquatic ecosystems' (METHANIAQ).

assistant: **Concept**

Aquatic ecosystems are a major source of the potent greenhouse gas methane, accounting for half of the global methane emissions. Biogenic methane is microbially produced in anoxic sediments and typically rapidly consumed by methanotrophic microorganisms, largely limiting emissions to the atmosphere. However, methane concentrations are often elevated in oxic surface waters of oceans and lakes (“methane paradox”). Aerobic methane production in surface waters might constitute a particularly important source of methane, which, due its proximity to the atmosphere, might escape the aquatic “microbial methane filter”. Yet, we currently lack a comprehensive understanding of the involved processes and microorganisms. Moreover, enhanced eutrophication of coastal ocean and lake ecosystems has been linked to increased methane emissions. Despite the immense importance of methane-cycling microorganisms in controlling emissions from these systems, we know remarkably little on how changes in environmental conditions affect their in situ activities.The METHANIAQ project addresses these knowledge gaps by 1) resolving and quantifying aerobic methane production in surface waters of aquatic ecosystems with different trophic states, and 2) unravelling how eutrophication affects methane-consuming microorganisms in water columns of coastal ocean and lake ecosystems. To tackle these objectives, I will use an innovative combination of approaches, comprising in situ measurements of biogeochemical process rates, manipulation experiments under controlled laboratory conditions, and cutting-edge molecular methods to analyze microbial communities. The proposed approaches will provide an integrated view from the scales of enzymes and microorganisms to ecosystem-level processes spanning marine and fresh
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'PROVENTA Smart Database Transformation Framework' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The execution of database migrations traditionally involves costs and risks that are difficult to evaluate previously. 40% of all migrations fail or exceed their budget and schedules. This prevents many organizations from implementing necessary changes to integrate better technologies, resulting in an extremely negative effect on their competitiveness in the long term.Major database vendors offer database migration tools to facilitate the adoption of their newest products, however, these tools focus only on database transformations to the vendor’s products and are only commercialized attached to the vendor package, which reinforces the vendor lock-in. Furthermore, migration tools focus on minimizing the impact of the migration process, without taking appropriate actions to avoid post-migration operational risks.At Proventa, we have gradually developed a series of custom utilities, based on commercial Open Source software, specifically for the purpose of database transformations. These tools have been progressively bundled into one single standalone package, called Datatrans. Datatrans constitutes a revolutionary standalone framework that drastically facilitates the transformation process for all the major database management systems.By releasing Datatrans as a commercial product, we will minimize migration project risks and encourage database transformations towards state-of-the art Open Source across all industries. This will result in a reduction of license costs, an improvement of general productivity and cost-efficiency. Additionally, this will also contribute to the general sustainability of Open Source database management software.For Proventa, on top of boosting our product revenues, it will also attract new customers and complement our current offer of consultin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Continuous monitoring of the harmfull flue gas components born in mixed waste incineration' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The amount of waste taken into landfill sites is to be decreased. Therefore, incineration of waste is increasing. Mixed waste is very challenging fuel to incinerate because it comprises of components like plastics, metals and bio waste that forms harmful substances while burning. It is possible to reduce the amount of harmful substances using flue gas cleaners and controlling the combustion process. In order to control the emissions of these harmful compounds continuous and on-line monitoring is needed. Currently there are not available continuous monitoring apparatus for many of these harmful flue gas components (e.g. dioxins and furans) . The ultimate objective of the project is to accomplish an analyzer/analyzers that can be used for measuring and monitoring concentrations of the most harmful flue gas components born in the incineration of mixed waste continuously.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Belgian EU Presidency Conference on Infrastructures for Energy Research'.

assistant: **Innovation**

The project aims to organize a conference on Infrastructures for Energy Research (ENERI 2010) during the Belgian Presidency of the European Council. The conference will be a 1.5 day event held in Brussels in the new conference facilities Square Brussels Meeting Centre on the 29th and 30th of November 2010.The target group is the scientific community, R&D and science policy managers, the energy sector and industry, policy decision makers (250-300 participants, on invitation only).The conference aims to contribute:-to the development of a comprehensive strategy for research infrastructures in the energy  field at pan-European level, in the framework of the European SET-Plan and of the ESFRI Roadmap,-to the analysis of the impact of RIs (including e-infrastructures) on the implementation of energy policies and sustainable development and-to the identification of possible actions to increase the human capital affecting the implementation of the energy research projects.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The Intra- and Inter- Host Evolutionary Dynamics of HIV' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

This research proposed involves a comprehensive and ground-breaking analysis of the evolutionary dynamics of the immunodeficiency virus (HIV), the causative agent of AIDS. Central to this project is the analysis of the different modes of virus evolution wi thin individual patients and the evolution of the virus within an infected population. Although these temporal scales are related, there is good reason to believe that the evolutionary process differs fundamentally within and among hosts, although to date this has not been properly investigated. The main objective of the project is to determine the similarities and differences between HIV evolutions on an intra- and inter- host level, the relative strength genetic drift and natural selection at this level, of how these shape the evolution of HIV in the long-term, and from this to create a unified model of HIV evolutionary dynamics. Another key objective of the project is to develop computational methods and computer software to measure the evolution, fixati on rate, and fitness effect of HIV mutations. The objectives will be achieved by using a number of different methodical processes to analyse a variety of sequence data sets either extracted from public databases or generated in collaborative projects. The fellowship program will result in the training of a Portuguese scientist by one of the world leading groups on the field of viral evolution. This top quality training will provide the scientist with an understanding of the processes involved in shaping the evolution of the virus in a given population. The training will also equip him with the tools needed for the creation of mathematical models, and bioinformatics software used in the analysis of the evolutionary dynamics of HIV. This research will assist i n the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Multi-scale modelling of interfacial phenomena in acrylic adhesives undergoing deformation' (MODIFY).

assistant: **Innovation**

In soft nanostructured materials containing polymers (such as acrylic adhesives), interfaces pose specific challenges since they are usually diffuse and can transfer stress through chain entanglements. The equilibrium structure of soft polymer interfaces is well-known, but their mechanical strength remains poorly understood. Yet many new nanostructured materials contain internal interfaces and important applications involve a contact between the soft polymer and a hard substrate. The detailed understanding and modelling of the mechanical response of these interfaces is challenging and currently prevents the use of modelling as a screening tool for new materials in important applications. We will address these problems through a specific example of application where interfaces dominate materials performance: i.e. soft nanostructured adhesives. The objectives of MODIFY is to obtain a fundamental understanding of the complex interfacial structure-related interactions in these materials through sophisticated multi-scale modelling by addressing the following issues: (i) The mechanism(s) of stress transfer at internal interfaces between soft latex particles; this needs to be done at different scales from the molecular entanglement to the finite element level. (ii) The mechanism of stress transfer at hard/soft interfaces between the substrate and the soft adhesive. (iii) The effect of the presence of multiple internal interfaces on the macroscopic rheological properties of the material, and (iv) The respective role played by the polymer rheology and the interfaces in controlling the complex deformation field experienced by the soft adhesive during debonding. If successful, we expect that the economic impact of MODIFY will lie in the design by the industrial partners with knowl