RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'A Quantum Non-Demolition Microscope' under Seventh Framework.

assistant: **Concept**

QuantumProbe will devise a novel microscope to probe and fully control the intriguing properties of quantum systems, formed by neutral atoms trapped in optical lattices. This includes in particular the possibility of in-depth quantum state characterization as well as engineering arbitrary quantum correlations. The microscope’s achievements will go far beyond standard state-of-the-art detection and manipulation capabilities in both, top-down approaches using large quantum gas systems, and bottom-up approaches with single particles.For this purpose, single or few well controlled neutral atoms will be immersed as “quantum-probes” into a quantum target system, a Mott-insulating state of another atomic species. Hence, QuantumProbe extends the concept of scanning microscopy to a single atom based coherent microscope, capable of parallel multi-tip operation with more than one probe atom. The fundamental measurement mechanism of this microscope is the entanglement between probe and target atoms, induced by coherent inter-species interaction, and subsequent detection of the probe atom’s state. QuantumProbe will thereby enable local, quantum non-demolition measurements of atom number or spin state as well as local, coherent manipulations such as spin flips and controlled-NOT quantum gates within the Mott-insulator.QuantumProbe will pave the way for break-throughs in various fields of research and practice: It will introduce local, fundamental quantum gates in scalable many-body systems, highly relevant for implementations of quantum information processing and quantum computing strategies; help elucidating the classification and quantification of multi-particle entanglement, which is even theoretically not fully clear; allow local coherent spin state engineering and read-out, open
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'String Theory, QCD and Black Holes' (STRINGBH), addressing dissemination and exploitation.

assistant: **Impact**

I intend to use string theory to understand gauge theories in 4 dimensions, both at strong and weak coupling. This includes describing strongly interacting gauge theories using their supergravity duals, and understanding gauge theories at intermediate coupling via integrability. It also includes using and developing new string-inspired twistor-space techniques to analyse QCD and N = 1 amplitudes at one loop level. I also plan to thoroughly investigate the implications of string theory for the physics of black holes.In particular I am interested in constructing and analysing black hole microstates - smooth horizon-less solutions that are very similar to the black hole asymptotically, but differ from the black hole at the location of the horizon. Counting and understanding these microstates via the AdS-CFT correspondence will help establish whether black holes should be thought of as ensembles of such microstate geometries.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on '5th workshop on three-Dimensional Modelling of Seismic Waves Generation, Propagation and their Inversion'.

assistant: **Innovation**

The International Centre for Theoretical Physics (Trieste) in collaboration with Institute of Geodesy and Geophysics of the University of Trieste, now department of Earth Sciences of the University of Trieste has been organizing workshops on studies of seismic wave propagation and earthquake source studies in a realistic three-dimensional Earth and on methods for inversion of seismic data since 1992. Indeed analysis of seismic records help us improve our understanding of both earthquake rupture mechanisms and the deep structure of the Earth, its evolution and dynamics. Hence efforts have been devoted at: - improving our understanding of seismic wave generation by natural and artificial sources and their propagation through complicated Earth structures. For the last few years, because of the development of fast, large memory computer systems, tremendous progress has been made for modelling seismic wave generation and propagation. Some of the methods are purely numerical, others are hybrid combinations of analytical and numerical methods.They are used now for solving inverse problems of seismology like reconstructing three-dimensional Earth structures, or modelling seismic sources. These methods have completely changed our approach to event detection, location identification and wave propagation in heterogeneous, anisotropic, and non-linear, media.The workshop will cover practically all aspects of the above-mentioned problems, i.e. theory of wave propagation, simulation techniques and methods of inversion of seismic wave fields. Special emphasis will be placed on the following application: - Global, regional and local studies of the Earth structure for diverse scientific and applied purposes; - Detailed investigations of earthquake-prone areas, including major faulting zo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Assessment of dermal absorption of organic flame retardant chemicals using 3D-in vitro human skin models' to be submitted under Seventh Framework.

assistant: **Abstract**

ADAPT is a supradisciplinary study that combines advanced environmental analytical chemistry with state of the art human tissue culture techniques to study the toxicokinetics of human dermal exposure to organic flame retardants (FRs) in indoor dust and domestic products. The overarching hypothesis that current research in this field must test is that FRs present in many consumer goods and building materials are contaminating indoor dust at concentrations that constitute an important pathway of human exposure to these chemicals, at levels that are detrimental to human health. While some studies have reported correlations between FR concentrations in dust and in human tissues, and dermal contact with contaminated dust and consumer products has been highlighted as an important pathway of human exposure to FRs, no information is currently available on the human dermal absorption of these chemicals. This lack of information hinders the development of accurate risk assessment studies. ADAPT aims to fill this major research gap by using novel in vitro methods to study human dermal absorption of various legacy and novel FRs present in indoor dust and consumer products through experiments mimicking real-life exposure scenarios. The results of these experiments will be used to develop an advanced pharmacokinetic (PK) model to further understand the relationship between external human exposure to FRs in indoor environments and human body burdens of these contaminants. ADAPT’s vision is that improved understanding of various aspects of human exposure to FRs will provide for more accurate risk assessment studies which will benefit public health, policy-makers, regulators, and scientists by delivering more effective approaches to monitoring human exposure to such chemicals.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Semantic audio-visual entertainment reusable objects'.

assistant: **Concept**

SALERO's goal is to define and develop 'intelligent content' objects with context-aware behaviours for self-adaptive use and delivery across different platforms, building on and extending research in media technologies, web semantics, and context based image retrieval, to reverse the trend toward ever-increasing cost of creating media.SALERO aims to advance the state of the art in digital media to the point where it becomes possible to create audiovisual media for cross-platform delivery using intelligent content tools, with greater quality at lower cost, to provide audiences with more engaging entertainment and information at home or on the move. The RTD addresses:- Understanding the relations between media types, genres, workflows and styles- Metadata, Media Semantics and Ontologies for semantically aware content objects- Practical methods of context-based information retrieval of characters, sounds, images, movements or behaviours- Procedures for manipulating the appearance, sound, movement and behaviour of semantically aware characters and objects- Improved methods and tools for script translation and speech synthesis- Software toolkits, systems, plug-ins and interfaces for control of appearances, sounds, semantic behaviour and properties of intelligent content objectsSALERO will guide, validate and evaluate the R and D through experimental productions across a range of important media genre, based on scenarios defined by artists and creative media professionals. It will also reinforce the European skills base by developing training structures for professionals and researchers and prepare the market launch of technologies through a series of Demonstration Testbeds for media professionals.The RTD programme includes long-term research and medium-term work designed to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'An innovative polymer particle used for textile dying which massively reduces water and energy consumption'.

assistant: **Innovation**

The textile industry is a major contributor to global water consumption . In India alone, 1.6 billion litres of water are used dailyin the textile industry. Given that only 2.5% of the Earth’s water is freshwater and only 0.3% is accessible to humans, this isclearly unsustainable and grossly wasteful. In addition, industrial manufacturing in the textile industry is responsible for 20%of all water pollution making it the number one polluter of clean water after agriculture.The dyeing process is the prime contributor to much of the water, time and energy consumption that takes place in the textileindustry. On average, 60-80 litres of water are needed to dye 1kg of cotton and 80% of the total energy and 65% of themany environmentally hazardous chemicals produced in textile production are a result of the dyeing process. In addition,dyeing is also by far the most time-consuming process involved.Growing populations and consumer needs are demanding more efficient and faster production than ever. Our solution is anauxiliary technology, H2COLOR AUX. A revolutionary system developed by expert chemists that prevents hydrolysis in thedyeing process. This greatly reduces the amount of energy, chemicals and time required for dyeing textiles. A similartechnology is used in our H2COLOR pigments which have superior properties than alternatives, while being less toxic andmore environmentally sustainable. Uponcommercialisation, we will save the world billions of litres of water per day, eliminate a globally leading polluter, increasetextile production by 50%, and reduce costs for a multitude of industries.Customers of Ecofoot will have access to a highly-efficient, affordable, and easy-to-use dye-auxiliary product that saves 70%of the water, 80% of the energy, 50% of the process time, and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Proteomics data collection' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Based on the work of the Human Proteomics Organisation (HUPO) Proteomics Standards Initiative (PSI), we will coordinate the development and implementation of international standards for the representation of high-throughput Proteomics data. Focus will be on standardised data collection, and furthermore on standardised data analysis of protein identification by mass spectrometry. We will establish the basis to develop an international data exchange network of Proteomics data repositories.  This will include the implementation of prototypes of automated data submission pipelines in the leading European laboratories. Participants will be major European Bioinformatics tools developers and Proteomics data providers, and experts from non-European countries and invited Industry Partners to ensure the highest possible international standard.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Understanding  Circumventing Antibiotic REsistance' (2014-2020).

assistant: **Innovation**

The evolution and spread of antibiotic resistance has become a public health concern of the utmost severity, making once treatable diseases deadly again and undermining our living standards. New therapies are imperative, but equally important are the understanding of the full repertoire of drivers of antibiotic resistance and the identification of ways to counteract them. We have recently established that ~250 non-antibiotic drugs have direct, strong and often broad antibacterial effects on human gut microbes. Moreover, preliminary data indicate that bacteria use similar general resistance mechanisms against both drugs with human targets and antibiotics. This implies that polypharmacy may be a hitherto unnoticed driver of antibiotic resistance. We will use chemical genetics and experimental evolution to systematically map the cross-resistance between human-targeted drugs and antibiotics, and elucidate underlying resistance mechanisms. Using these data, we will next seek to identify antidotes for the antimicrobial side-effects of non-antibiotic drugs, and exploit human-targeted drugs for reverting existing antibiotic resistance. At the genetic level, we will use high-throughput reverse genetics to expose the Achilles heels of bacterial cellular networks for resistance development. Finally, we will uncover the antimicrobial mode of action of tens of human-targeted drugs using thermal proteome profiling and chemical genetics. Together with the genetic information, this line of research will yield design principles and possibly new drug candidates for longer-lived, resistance-proof drug combinations. Overall, this project aims at improving our fundamental biological understanding of antibiotic resistance and the paths to prevent, delay or revert it. It can also set the basi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Protein-engineering based approach for super-resolution imaging of nucleoporin-chromatin interactions' in the context of a Seventh Framework call.

assistant: **Objectives**

Nucleoporins are major building blocks of the nuclear pore complex (NPC). In addition to their role in the nucleocytoplasmic transport, a subset of nucleoporins have additional gene regulatory roles. They can bind chromatin and chromatin modifiers, either directly at the NPC or in the nucleoplasm, leading to gene repression or activation. Due to a lack of techniques that allow mapping spatial and temporal heterogeneities of individual proteins with high precision, the molecular mechanisms underlying these phenomena are far from being understood. To overcome this, I will develop a combined protein-engineering/super-resolution approach for single amino acid targeted labelling and tracking of proteins inside the cells. This strategy is based on the translational incorporation of newly developed non-canonical amino acids (ncAAs). These ncAAs are suitable for inverse-electron-demand Diels-Alder reaction, a special type of highly selective and rapid “click-chemistry” reactions proceeding in a non-toxic and fully biocompatible way inside living cells. I will employ this technology to systematically label a set of nucleoporins and chromatin modifiers with small dyes. The high photostability of these fluorophores permits long-term imaging and will allow me to identify nucleoporin binding partners in cultured mammalian cells with nanometer resolution. This will set the stage for a technology that enables deciphering protein plasticity in vivo at the molecular level and provide novel insights into multifunctionality of nucleoporins.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Sustainable technologies for the production of biodegradable materials based on natural chitin-nanofibrils derived by waste of fish industry, to produce food grade packaging' to be submitted under Seventh Framework.

assistant: **Abstract**

The food sector (including beverage industry) accounts for approximately two thirds of global packaging and about 50% of these packages are made of plastics. Plastic food packaging materials currently in use are generally non-biodegradable causing ecological imbalance and aesthetic deterioration of nature. At the same time being a petro-chemical based product, plastics rely on a depleting and increasingly costly natural resource with relatively low LCA performance (high CO2 footprint).Food packaging – which is predominantly produced by SMEs - is crucial as physical and barrier protection keeping foodstuffs clean, fresh, and safe for consumers while increasing shelf life. Bio-based plastics offer a highly promising alternative and new biological materials are emerging as potential feedstock, such as chitin waste material from the fishing industry, mostly used in cosmetics applications due to their inherent bacteriostatic properties. Chitin waste exceeds 250 billion tons/year, and is considered hazardous due to its high perishability and polluting effect, both on land and sea. So re-use and up cycling to higher value applications would establish an important step forwards towards resource efficiency, providing a relevant innovation for the SME packaging industry that is under pressure to reduce cost and respond to environmental concerns. Recent research results at the University of Prague, leveraging on an SME owned world-wide patent (MAVI) for the production of chitin Nano fibrils, show interesting additional application opportunities of chitin as a bio-based polymer. The n-CHITOPACK project will leverage on the inherent superior properties of these chitin nano-fibrils for the development of new food packaging materials that are bacteriostatic, 100% bio-degradable and ca
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Second Order nano-Oxide Nonlinear Disordered phOtonics' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Despite the growing demand of simple and robust nonlinear optical devices, efficient optical conversion is still obtained by imposing stringent phase matching conditions on the nonlinear optical material (NLOM), critically increasing the fragility and the cost of nonlinear optics applications . The search for alternatives NLOMs with relaxed phase-matching conditions have attracted a large interest, but none of the mature alternatives is expected to satisfy market’s requirements of easy-fabrication, scalability and low-cost.Disordered NLOMs have shown the biggest potential in this direction, giving evidence of efficient and large-angle conversion without the need of phase-matching tuning. However, only few of the several opportunities provided by optical disorder has been exploited for nonlinear conversion due to materials and fabrication limitations. Therefore, the combination of multiple conversion mechanisms could generate unconventional and powerful  phase matching mechanisms.SECOONDO aims at the realization of a new class of disordered NLOMs based on perovskite nanoparticles (nano-oxides) in which random phase-matching, light scattering and Mie resonances coexist, but are also independently controllable. We will explore a new physics in optical nonlinear conversion, which could open avenues to the realization of easy and efficient nonlinear optical device.The project takes inspiration from the complementary competences of the candidate in disordered photonics and of the supervisor in nonlinear nano-oxides generating new knowledge on both sides. The candidate will acquire new competences in nonlinear nano-optics and in material sciences, which combined to his past knowledge, will make his profile unique, ensuring independence and a strong future career.