RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'OPTimising IndiGOidine production heterogeneity for sustainable microbial blue pigment biosynthesis' (OPTIGO).

assistant: **Concept**

The textile industry is a major global contributor to environmental pollution, primarily due to the harsh conditions and hazardous chemicals used in fabric pre-treatment, dyeing, and finishing processes1. Notably, the chemical synthesis of dyes such as indigo, best known for its use in jeans manufacturing, contributes to this burden. With growing demands for clothing and fabrics, there is a desperate need for more sustainable alternatives. One potential solution is the use of microbial alternatives to indigo, with a similar colour spectrum and dying capacity. Our lab recently engineered a microbial factory for production of blue dyes using the industrially relevant yeast Yarrowia lipolytica and we have registered a patent due to promising yields during small-scale fermentation. In our latest research to improve production yields, we noticed a remarkable difference biosynthesis at the single-cell level, with some cells containing tenfold amounts of the pigment. Building on our recent research funded by the ERC starting grant DEUSBIO to understand metabolic single-cell heterogeneity, this proposal aims to characterise drivers of production heterogeneity during Y. lipolytica fermentation. Furthermore, we intend to harness production heterogeneity by engineering stable high producer populations, to optimise bioproduction and increase overall yields. This research will be pivotal for improving the economic viability of sustainable dye production and for developing an optimized microbial host with broader applications in biomanufacturing processes. By establishing a proof of concept (PoC) through this research, we anticipate potential collaborations with industrial partners, paving the way for the commercialisation of sustainable blue pigment production.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Sensation and inferences in perception, metacognition and action' under Horizon 2020.

assistant: **Concept**

The perceptual experience of humans is seamless, although there are major spatial gaps in the available sensory information due to internal (e.g. absence of photoreceptors in the blind-spot) or external reasons (e.g. occlusion by other objects). While the contents of these sensory gaps seem to be completed by inferences, it is unknown how those inferences are dealt with in further processing compared to veridical sensory information. Recently, we and others showed that inferred information is preferred over sensory information in metacognition. This contradicts one of the axioms of current thinking about human information processing, according to which information is weighted by its reliability.SENCES aims to investigate the processing and usage of inferred information in comparison to veridical sensory information. First, we will use psychophysical and behavioral experiments to understand the role of inferences in perception, metacognition and action. Second, we will use EEG to distinguish between different models concerning the neural processing of inferences. Third, we will assess the role of inferences in pathological retinal scotomata and their plasticity along three time scales: across the lifespan by comparing healthy observers and patients experienced with missing sensory information due to long-term visual disorders; in the mid-term by studying the progression of pathological retinal scotomata in patients; in the short-term by training healthy observers with artificially missing sensory information.SENCES will provide crucial insights into how a seamless perceptual experience is constructed and how it is shielded from gaps in sensory information. Studying different phenomena of perceptual completion will allow for the discovery of general principles. Finally, i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Altermagnetism and spintronics without magnetization and relativity' (ALTERMAG).

assistant: **Concept**

Magnetically ordered crystals are traditionally divided into two basic phases -- ferromagnetism and antiferromagnetism. The ferromagnetic order offers a range of phenomena and device applications. The vanishing net magnetization in antiferromagnets is potentially favorable for spatial and temporal scalability of devices. Recently, our team and others have predicted instances of strong time-reversal symmetry breaking and spin splitting in electronic bands, typical of ferromagnetism, in crystals with antiparallel compensated magnetic order, typical of antiferromagnetism. Our central idea, resolving this apparent fundamental conflict in magnetism, is that symmetry classifies a third basic magnetic phase. Its alternating spin polarizations in both crystal-structure real space and electronic-structure momentum space suggest a term altermagnetism. We will demonstrate that altermagnets combine merits of ferromagnets and antiferromagnets, that were regarded as principally incompatible, and have merits unparalleled in either of the two traditional basic magnetic phases. In Objective 1 we will establish materials landscape of altermagnetism and, in Objective 2, show how its anisotropic (d-wave) nature enriches fundamental physics concepts of lifted Kramers spin-degeneracy, Fermi-liquid instabilities and electron quasiparticles. This will underpin our development of a new avenue in spintronics, elusive within the two traditional magnetic phases, based on strong non-relativistic spin-conserving phenomena, without magnetization imposed scalability limitations, and with complex functionalities.  In Objective 3 we will demonstrate altermagnetic giant-magnetoresistive multi-layer memory devices. In Objective 4 we will realize logic-in-memory analog functionalities in single-layer nano-
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Conservation of the barbel - barbus barbus - l.- cyprinidae- for riverine sport fisheries' (1994-1998).

assistant: **Concept**

This study aims to aid conservation of the barbel Barbus barbus through the development of a recruitment model to help predict fluctuations in year-class strength due to variations in climatic conditions and water pollution levels. The objectives to achieve this aim will be to: 1) determine the impact of elevated suspended matter and nutrient levels on barbel reproduction; 2) estimate the mortality of barbel eggs, larvae and juveniles in the field and laboratory; 3) investigate the emergence and dispersal behaviour of young barbel; 4) develop a mathematical model for predicting year-class strength 5) offer suggestions for management strategies for the restoration of the barbel's natural habitat. The deliverables expected to result from the proposed study are: 1) a series of articles in high-quality, peer-reviewed international scientific journals; 2) a mathematical recruitment model for predicting year-class strength; and 3) recommendations for management strategies for the restoration of the barbel's natural habitat.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Development of Culturally Appropriate Neuropsychological Tests for the Greek Population' (DECANT) targeting Seventh Framework.

assistant: **Abstract**

We aim to explore and demonstrate the flaws inherent in the current practice of transferring neuropsychological tests from American or other Anglo-Saxon societies to other countries and cultures and to develop an empirically-based and scientifically sound conceptual framework within which potential pitfalls in culturally sensitive neuropsychological assessment and test development can be avoided. This will lead to the development of a method for creating or adapting a culturally appropriate neuropsychological measure to any culture. We expect our findings to be of interest not only to scientists and clinicians from any European country that is currently developing the field of neuropsychology, but even those in non-European developing countries, as well as those working with ethnic and racial minorities in Western countries. While this project is relevant to all cultures, we will use the Greek case both as an example and a springboard to creating and norming neuropsychological measures that are appropriate for a given culture. The aims of the proposed investigation are in accordance with international trends in cross-cultural neuropsychology. On an applied level, we will provide a guide for the development of culturally appropriate tests for the Greek population and similar cultures, and yield a series of neuropsychological tests for use in clinical evaluations and research protocols. More importantly, perhaps, on a theoretical/scientific level, we will challenge some of the underlying assumptions in the field of ability measurement and offer new insights regarding the universality of the constructs typically measured in a neuropsychological assessment. Therefore, this work will enhance European competitiveness by challenging the current worldwide dominance of North Ame
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Continuous Downstream Processing of Bioproducts'.

assistant: **Innovation**

Continuous biomanufacturing is one of the grand challenges of Europe’s bio-industry. It offers a significant opportunity to boost productivity, improve competitiveness and to reduce the environmental footprint. Current progress is impaired by shortage of trained engineers and scientists, who can design and control continuous biomanufacturing processes. This Innovative Training Network (ITN) will focus on addressing the critical gaps in research training to enable advances in continuous downstream processing. An expert consortium of nine industry partners, eight universities, one research organisation, a regulatory institution and a business consultancy has developed a research and training programme to address the most urgent topics in continuous downstream processing. These are: (1) process control and modelling (including economic modelling), (2) miniaturization, scale-up and scale-down of unit operations and (3) process design and development of integrated continuous downstream processes. Furthermore, regulatory framework questions, such as comparability of product quality between batch and continuous processes will be addressed. Adding the regulatory and environmental aspects to the scientific, technological and economic approach, makes our program interdisciplinary, comprehensive and unique. Specific Ph.D. topics for 15 ESRs have been outlined. The presented research and training programme will equip the ESRs with the scientific and important transferable skills, such as IPR, entrepreneurship, data management and innovation management. The consortium’s strong track record in the management of interdisciplinary research and training will ensure effective and timely training of the next generation of leaders able to design innovative continuous facilities of the futu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Support for clinical trial capacity platform for sleeping sickness in Africa' (HATCAP).

assistant: **Concept**

Human African trypanosomiasis (HAT), known as sleeping sickness, is fatal if left untreated and a most neglected disease in Africa. An estimated 350,000 people are infected in 36 countries, the majority living in Angola, DRC, Uganda, Sudan and RoC. New di agnostics and treatments are urgently needed. Diagnostics require invasive methods and lack sensitivity and specificity. Drugs in use are old, toxic, losing efficacy, and require prolonged therapies. For over forty years, negligible clinical research has been done for new HAT treatments; thus, clinical research infrastructure and professional capacity in disease endemic countries is extremely limited. With new treatments in the pipeline, constraints in clinical evaluation and registration of new interve ntions for HAT must be urgently addressed. In August 2005, DNDi sponsored a regional workshop on HAT Clinical Trial Capacity that brought together endemic country HAT disease specialists and European clinical research and disease experts. This initial me eting resulted in the formation of a regional group who will work together to determine and implement a strategy to create sustainable regional and national clinical trial capacity for HAT. The present proposal seeks specific support for the primary acti vities of this group, which will include: HAT clinical trial methodology development Strengthening & harmonising regulatory practices throughout the region Developing strategies for national policy change Targeted HAT clinical trial capacity stren gthening Implementation will be through north-south and south-south exchange of expertise and best practice, specific training and workshops, and concurrent participation in clinical studies. Support to this project will enable the disease endemic count ries to conduct quality
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Innovative Eco-Technologies for Resource Recovery from Wastewater' (INCOVER) targeting Horizon 2020.

assistant: **Abstract**

Taking into account the current global water scarcity and the expensive operation and maintenance cost of wastewater treatment, INCOVER concept has been designed to move wastewater treatment from being primarily a sanitation technology towards a bio-product recovery industry and a recycled water supplier. A wastewater specific Decision Support System methodology will be tailored to the INCOVER technologies and provide data and selection criteria for a holistic wastewater management approachThree added-value plants treating wastewater from three case-studies (municipalities, farms and food and beverage industries) will be implemented, assessed and optimised concurrently. INCOVER plants will be implemented at demonstration scale in order to achieve Technology Readiness Level(TRL) of 7-8 to ensure straightforward up scaling to 100,000 population equivalents (PE). INCOVER added-value plants will generate benefits from wastewater offering three recovery solutions: 1) Chemical recovery (bio-plastic and organic acids) via algae/bacteria and yeast biotechnology; 2) Near-zero-energy plant providing upgraded bio-methane via pre-treatment and anaerobic co-digestion systems; 3) Bio-production and reclaimed water via adsorption, biotechnology based on wetlands systems and hydrothermal carbonisation. To improve added-value production efficiency, INCOVER solutions will include monitoring and control via optical sensing and soft-sensorsINCOVER solutions will reduce at least a 50% overall operation and maintenance cost of wastewater treatment through the use of wastewater as a source for energy demand and added-value production to follow UE circular economy strategy. In addition, strategies to facilitate the market uptake of INCOVER innovations will be carried out in order to close the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Collaborative Rover Operations and Planetary Science Analysis System based on Distributed Remote and Interactive Virtual Environments'.

assistant: **Concept**

CROSS DRIVE targets on creating the foundations for collaborative distributed virtual workspaces for European space science. Space exploration missions have produced huge data sets of potentially immense value for research as well as planning and operating future missions. However, currently expert teams, data and tools are fragmented,  leaving little scope for unlocking this value through collaborative activities.The question of how to improve data analysis and exploitation of space-based observations can be answered by providing and standardizing new methods and systems for collaborative scientific visualisation and data analysis, and space mission planning and operation. This will not only allow scientist to work together, with each other's data and tools, but importantly to do so between missions. The consortium brings together unprecedented expertise from space science, scientific visualisation, virtual reality and collaborative systems. The proposed collaborative workspace encompasses various advanced technological solutions to coordinate central storage, processing and 3D visualization strategies in collaborative immersive virtual environments, to support space data analysis.A specific focus is given to the preparation of the ExoMars 2016 TGO and 2018 rover missions. Three case studies will demonstrate the utility of the workspaces for European space science: Mars atmospheric data analysis, rovers landing site characterization and rover target selection during its real-time operations. The use cases will exploit state-of-the-art science data sets and they will be constructed in view of the ESA ExoMars missions’ scenarios. Impact on beneficiaries will be maximised both through providing an expandable backbone and reusable standardisation and tools, and three level
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Herbivore-induced terpene biosynthesis in plants: a study of its regulatory enzymes in cucumber' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Many plants respond to a herbivore attack, e.g. spider mite, by the production of a volatile blend, which attract predators of the herbivorous spider mite. This project will identify and characterise plant genes involved, followed by a phenotypic study of altered volatile composition.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Bioinspired superhydrophbic wax surfaces to eliminate biofilm formation in the food industry' to be submitted under Horizon 2020.

assistant: **Abstract**

Microbial food spoilage leads to food-borne illnesses and food wastage.  It is estimated that food borne disease cause 23 million illnesses and 5,000 deaths only in the European region   and around 88 million tonnes of food are wasted annually. Contamination of food by biofilms can occur at any stage of the food production process or consumption. In this PoC we propose to address this problem taking inspiration from nature. We have shown that we can emulate various plant leaf surfaces by synthetic paraffin waxes which exhibit superhydrophobic and pronounced passive anti-microbial properties. These waxes are FDA approved for the use in food products. We plan to develop easy to apply waxed surfaces via spray and dip coating techniques, which can be easily implemented into the food industry at various stages of production. We believe this will allow to significantly reduce food spoilage and waste.