RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Pt (ii) and pd (ii) complexes with oligonucleotides and dna constituents as virus inhibitors' (1998-2002).

assistant: **Innovation**

I would like to invite you to join our research group working in the area of nucleic acids. The research is supported by the Slovenian Government Research Programme entitled: 'Synthesis and Structural Studies of Biological Macromolecules' which is tightly connected to COST-D- 20 Programme- 'Metal compounds in the Treatment of Cancer and Viral Diseases'. We can offer an excellent training in nucleoside and nucleotide chemistry having all crucial chemicals in hand. DNA synthesizer is available next to all necessary equipment for NA structure determinations. The programme is focused on higher order molecular complexes namely on hybridization studies of appropriate duplexes, triplexes and quadroplexes mainly resulted from guanine rich oligonucleotides. Pt(II) and Pd(II) interactions will be studied either with NA constituents analogues or with specially designed and targeted oligonucleotides. Excellent NMR (600 MHz), mass-spectral and X-ray facilities will be provided for. We can certainly advertise our expertise in coordination chemistry which we perform in collaboration with other members of COST -D20 action. These positions are available immediately for the periods from 3-months up to 12 months. This training is especially recommended for individuals who want to work in bio-inorganic area on biological mechanisms of platinum drugs.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Towards understanding of tree growth regulation'.

assistant: **Innovation**

Foreseen ResultsAs soon as candidate growth and development-related genes will have been identified, sense and antisense constructs will be introduced into Malus, Prunus and Vitis plants, using transformation procedures already in use in participating laboratories. After initial characterization of transgene copy number and expression features, transgenic woody plants showing increased or decreased expression of the genes of interest will be selected and micropropagated. Using the same tissue culture conditions that will have been used to select development-related genes, these transgenic plants will be scored for morphological modifications. After transfer to greenhouse conditions, these plants will also be screened for growth and development alterations in vivo.Many of the regulatory circuits underlying plant growth and development processes still remain to be discovered and understood. However, it has become increasingly clear that basic signal perception and transduction mechanisms (involving cytoplasmic calcium ions) and their associated biochemical cascades play a key role in these phenomena, like in many others. From this point of view, the regulation of tree growth and shape constitutes one of the most challenging issue, not only because of its apparent complexity, but also because of its major impact on many agricultural or forestry problems.The development of plant molecular biology techniques has allowed to isolate tools that can now be used to understand, at the molecular level, some of these processes. Apple tree DNA probes, corresponding to genes whose products are likely to be involved in plant growth and development regulation, will be used to dissect molecular events related to the perception and transduction of developmental or morphogenetic signals. T
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Cities as Arenas of Political Innovation in the Strengthening of Deliberative and Participatory Democracy', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Gaps between political decision-making processes and citizens has become increasingly visible in Europe, particularly since the EU’s post-Millennial economic, political and security crises. In addition, general distrust of politics has been exacerbated by populist and neo-nationalist political forces that interpret the pluralistic and agnostic nature of democracy as a weakness. These and similar tendencies could have grave consequences through a further erosion of multicultural conviviality and social cohesion in Europe. Nevertheless, populism and political disaffection on a more general level are being met by counter currents of local political activism and an increasing consciousness of the political role of social movements in cities and urban areas. Cities have emerged as vital political arenas for the development of the European public sphere and the promotion of inclusion, social agendas and active citizenship. In addition, different forms of citizen participation have started to transform governance cultures of several large European cities, taking active roles in local elections, and becoming part of local political structures, from Paris to Istanbul. Based on several case studies and pilots of governance innovation initiatives we will investigate the ways in which social movements coupled with local government reform initiatives create momentum for political change that include more inclusive and participatory forms of governance. In EUARENAS we will target the following: 1)  the ways in which these practices emerge, the main actors, the strategies, methods and digital platforms they develop to attract attention and how they appropriate urban spaces, 2) economic, political and cultural factors influencing local outcomes, 3) horizontal and vertical governance im
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'A Non-Invasive Test for Guiding Follow–up of Patients with CT-Detected Lung Nodules' (LuMaSense).

assistant: **Innovation**

This PoC is a commercially-oriented spin-off from our “DIAG-CANCER” ERC project, addressing an urgent clinical need in the field of lung cancer (LC). The rationale behind this PoC is that CT-based LC screening programs are emerging in many countries worldwide. However, the high false positive rate of this technique (96% out of the 24% positive CT findings are non-cancerous) has been a major challenge in front those plans. This is because the CT-detected non-cancerous group has undergone unnecessary invasive procedures that are both costly and associated with significant morbidity and mortality. With this PoC project, we aim to increase the specificity of the LDCT based screening program by utilizing an auxiliary noninvasive breath test to distinguish between malignant and non-cancerous CT findings. The proposed breath test relies on a novel stand-alone device that provide an improved combination of speed, sensitivity, portability, low complexity, easy operation and low production cost. In order to transform our idea and current technology into a marketable device we propose taking several steps: (i) optimization of a prototype device and evaluation of its clinical usefulness through clinical studies; (ii) completing the IP portfolio of the device; and (iii) conducting detailed market research to identify the optimal placement in the healthcare market and possible competitors. After completing these stages, to be covered by the present grant, we propose to proceed to the technology transfer to a mature health care company or through complementary fund to advance the technological plans. If successful, the proposed PoC can be translated immediately into a powerful tool for the management of nodule-positive patients. It will both reduce the rate of unnecessary invasive pro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Advanced Hybrid Engines for Aircraft Development'.

assistant: **Concept**

Future demands on the air transport systems dictate that aircraft should be less polluting, less noisy and more fuel efficient. Also, in the long term alternative fuels like biofuels and hydrogen will replace the traditional jet fuel. The ACARE in Europe has identified that CO2 emission and perceived noise levels should be reduced by half and NOx emission be reduced by 80% by 2020. However recent ACARE studies indicate that these targets cannot be achieved using current incremental technological improvements. As the new ACARE environmental and efficiency targets for 2050 will be even more demanding, there is an urgent need for breakthrough technologies.The hybrid engine proposed in AHEAD is a novel propulsion system with a different architecture as compared to the conventional turbofan engine. The hybrid engine uses several unique technologies like shrouded contra-rotating fans, bleed cooling, dual hybrid combustion system (using hydrogen and biofuel under flameless conditions to reduce CO2 and NOx emission respectively). The hybrid engine proposed in AHEAD will constitute a leap forward in terms of environmental friendliness, will use advanced multiple fuels and will enable the design of fuel-efficient Blended Wing Body (BWB) aircraft configurations. The efficiency of BWB aircraft will be enhanced significantly due to embedded hybrid engines using the boundary layer ingestion (BLI) method. The project aims to establish the feasibility of proposed hybrid engine configuration and will demonstrate that the concept will substantially lower the engine emissions, installation drag and noise. The BWB configuration along with the proposed hybrid engine concept will bring in the much required breakthrough in civil aviation. The project will also evaluate the effect of LH2 stora
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Development and Manufacture Scoop Intake and Channel incl. ice and debris protection and acoustic absorbers' in the context of a Seventh Framework call.

assistant: **Objectives**

B.1.1 Concept and Objectives The concept of this project is to design and build a composite prototype scoop intake, incorporating the following key aspects of design • Acoustic panelling • Electro thermal ice protection • Lightning protection (if necessary) • Erosion protection • Temperature sensing The objective of the consortium team is to effectively trade the various design requirements to produce an optimised system solution. B.1.2 Progress beyond State of Art The project will investigate the integration both structurally and electrically of electro-thermal ice protection and acoustic absorbing panelling within a composite inlet scoop structure. It is not the purpose of this project to directly combine the ice protection and noise abatement technologies within the same area of scoop structure. A fully integrated, combined solution such as that is not viable within this project under the current budget; However, GKN does view this as an appropriate objective and a potential development area for future projects. By enabling this direct integration GKN expects significant noise reduction benefits. GKN sees potential in this entire application development area for offering technology progression. Work in this area to date has been focused on engine nacelle lip liner technology and has progressed well although additional support in this area would be necessary to continue the advancement.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Identity Attributes Matrix Initiative' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

IAMI aims to revolutionize entity identification and resolution in security, intelligence, and investigation contexts. It addresses the challenges and limitations faced by current identification techniques and offers a visionary solution through advanced AI-powered software. The project's long-term vision is to propel EU LEAs and security/intelligence organizations into a new era of intelligence, investigation, and forensic capabilities. IAMI's core innovation is the development of an AI-powered software system that can seamlessly integrate with existing case management systems and analytic tools. At the heart of IAMI is the concept of the 'Identity-Attributes-Matrix (IAM)', a 3D construct that encompasses a broad spectrum of multi-modal identity-related attributes, including biometric data, non-biometric identity-related data, and analytic results. These attributes are used to facilitate large-scale entity identification/resolution, including a broader range of entity types, simultaneous and rapid multi-entity identification/resolution, systematic and continuous analysis of flux of probe attributes, confidence in noisy/corrupted probe data, reduced false positive rates, access to contact attributes, and the ability to classify fake identities and bots/avatars. Furthermore, IAMI sets the groundwork for effective collaboration and data sharing across European agencies, including international organizations like EUROPOL and INTERPOL through the establishment of a new EU-Wide IAMI enrolled data collection repository for terrorist threat assessment and awareness which enriches their capabilities and assets.  The realization of IAMI's vision will be achieved through the demonstration of the developed IAMI solution. It will be communicated and disseminated among EU LEAs and s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Pre-transplant Renal Ex vivo Imaging and Multi-omics for Advanced Graft Evaluation' (PRE-IMAGE).

assistant: **Concept**

There is a considerable shortage of deceased donor kidneys. Hence, more organs of marginal quality need to be considered for transplantation. Transplant centers are increasingly utilizing ex vivo normothermic machine perfusion to better preserve donor kidneys prior to transplantation. Little is known about molecular pathways that are active while the organ is perfused ex vivo. Also, there is hardly any data on which molecular processes are relevant to assess organ quality during perfusion.I aim to determine the molecular mechanisms of ex vivo kidney perfusion prior to renal transplantation in order to develop breakthrough pre-transplant perfusion-based diagnostic markers that can indicate kidney transplant outcomes.First, a series of normothermic ex vivo porcine kidney perfusions will be conducted with repeated tissue and perfusate sampling. Ex vivo measurements will be contrasted with the contralateral kidney that remains in vivo. Genomics, transcriptomics, proteomics and metabolomics, as well as ex and in vivo magnetic resonance imaging followed by radiomics will be employed. Distinct molecular pathways will be identified which characterize an ex vivo perfused kidney, compared to the organ’s behaviour in vivo.Second, the discovered molecular pathways will be validated for human donor kidneys by performing ex vivo perfusions of discarded human organs followed by the same multi-omics approach.Finally, a prospective clinical study will be conducted with human kidneys that are perfused ex vivo prior to transplantation. With artificial intelligence analysis, tissue and perfusate multi-omics measurements and standard clinical variables will be associated with transplant results, to create advanced prediction models for post-transplant outcome.The high gain of my project wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Swarm of Micro Flying Robots' (2007-2013) under Seventh Framework.

assistant: **Objectives**

Autonomous micro helicopters are about to play major roles in tasks like reconnaissance for search and rescue, environment monitoring, security surveillance, inspection, law enforcement, etc. The ability to fly allows easily avoiding obstacles on the ground and to have an excellent bird's eye view. Therefore flying robots are the logical heir of ground based mobile robots. Its navigational and hovering advantages make them the ideal platform for exploration, mapping and monitoring tasks. If they are further realized in small scale, they can also be used in narrow out- and indoor environment and they represent only a limited risk for the environment and people living in it. However, for such operations today's systems navigating on GPS information only are not sufficient any more. Fully autonomous operation in cities or other dense environments requires the micro helicopter to fly at low altitude or indoors where GPS signals are often shadowed and to actively explore unknown environments while avoiding collisions and creating maps. This involves a number of challenges on all levels of helicopter design, perception, actuation, control, navigation and power supply that have yet to be solved.Our S and T endeavor proposed in this project will therefore focus on micro helicopter design, visual 3D mapping and navigation, low power communication including range estimation and multi-robot control under environmental constraints. It shall lead to novel micro flying robots that are: Inherently safe due to very low weight (around 500g) and appropriate propeller design; capable of vision-based fully autonomous navigation and mapping; able of coordinated flight in small swarms in constrained and dense environments.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'ENERGY EXTENSIVE PLANNING OF CITIES' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

The aim of this project is the implementation of advanced energy-saving and energy-efficient measures inside the frame-work of sustainable strategies in new built urban developments, in both building design and execution.The Expo-Cities Project will realize the urban planning activities in all sites incorporated in the project and will foster the construction activities so as the final settlement result will assure the initial goals. Local activities, however, will also be initiated by contracting of architects, consultants and craftsmen, (SME's), which will improve local employement-situation and the dissemination of local know-how.This project is bringing together four partners (Lisbon, Hannover,Palma de Mallorca and Utrecht) who are planning the construction of new buildings projects of vast dimension, between 1500 and 30000 accomodation units - and who are all going to start construction work still during this year and the rest will do during 1998.Brief description of the projects :- A brand new area to serve the expansion of Palma de Mallorca. The Balearic Islands capital. As any coastal city dominated by tourism with enormous cycling demands, a sustainable-yet attractive development is mandatory to create a model that serves the purpose to guarantee a development that can be assimilated by a close ecosystem as an island.- A renovation area in the city of lisbon serving the purposes of accomodating a world exhibition (Expo 98) with the imperative technological innovations involved in such events, and the challenge to reconvert the area into an expansion buffer of a growing city as Lisbon.- A new housing district in the city of Hannover built in the neighbourhood of the Expo 2000, 6000 houses including a special Expo-city" with emphasis on sustainable urban develome