RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Advancing Energy Conversion Technologies: High-Frequency Magnetics in Modern Power Electronics' (MAGNIFY).

assistant: **Concept**

Power electronics constitutes a core enabling technology in the energy transition decarbonizing our society. It is omnipresent in energy conversion applications linked to electrification and decentralization, such as renewable energy, storage integration, AC and DC microgrids, and electromobility. Wideband gap semiconductor technologies have been key for its rapid progress, and equally crucial are the high-frequency magnetic components, i.e. inductors and transformers. However, there is a lack of engineers with a comprehensive understanding of the whole chain and their intrinsic multiphysical and multiscale interactions: magnetic materials, magnetic component models, power electronic circuits and converters. MAGNIFY addresses this urgent need by focusing on three research objectives: 1) tailoring and characterising magnetic materials; 2) developping new efficient multiphysical and multiscale models of magnetic materials and components, integrating these models in the power electronic circuits; 3) aiming at a holistic system-level design of energy converters in several applications. MAGNIFY will exploit the expertise of the consortium to achieve these objectives and equipe 15 research fellows with the relevant skills and innovative tools to contribute to the development of energy- and cost-efficient power electronics to enable sustainable electrification. While becoming experts in the individual carefully chosen research topics, the participating companies will benefit from the generated magnetic material database, the more efficient and accurate models, the software tools, and the new design methodology. In addition, the research fellows will be exposed to different working environments owing to the involvement of five companies in the research and training program. Thi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Computation and plasticity in the cerebellar system: experiments, modeling and database (CEREBELLUM)' (CEREBELLUM), addressing dissemination and exploitation.

assistant: **Impact**

The long-term goal of this proposal is to understand how the cerebellum functions. Our approach is based on a tight interaction between computer modelling and experimental work.The work is organized around five scientific questions:- cerebella connections: what is the relation between in sag tally oriented microtones and the patchy maps of mossy fibber projections?- Functional organization of the climbing fibber system:does it strictly follow the capital microtones and can inhibition from deep cerebella nuclei uncouple livery neurons?- What is the physiological role of synaptic plasticity at the mossy fibbers to granule cell synapse?- What is the function of the glomeruli in the cerebella granular layer?- How does plasticity of parallel fibber synapses affect Purkinje cell firing and what is its relation to motor learning? In addition we will develop web accessible neuroinformatics database on the cerebellum and organize yearly scientific meetings.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Sequence specific Oligomers for in vivo DNA repair'.

assistant: **Objectives**

Sequence-specific alteration of genes in living organisms using small oligomers, as has been recently successfully demonstrated by us, could provide a new strategy for targeted gene repair or trait alteration. The applying consortium has in the last years developed a concept of using small dual oligomers to introduce in vivo site-targeted specific sequence alterations, and has advanced the toolkit for synthesis and functional testing of these oligomers using biophysical, biochemical and molecular biology methods.The oligomers (ROs) are composed of two functional domains: a targeting domain that provides high sequence affinity to any desired location in the genome, and a template domain that activates the cellular repair machinery by active group-transfer to induce small sequence changes without leaving foreign sequences. Hitherto the consortium has reached its goal of the 5th framework defined as in vivo rates of targeted sequence correction over 2% on a standardised cellular readout.The goal of the suggest ed work in the 6th framework is to further improve the design of platform technology to induce precise single-base changes in a cell culture readout at rates between 2 and 5% and in a selected disease locus without collateral damage. ROs provide a new paradigm for in vivo genetic engineering and a novel tool to be tested for its use in somatic gene therapy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'A new reconstructing technique using tissue engineering methods to create an engineered autologous vascularized  tissue flap', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Abdominal wall defects are often the consequence of severe trauma, cancer treatment and burns. These defects involve a significant loss of tissue, and often require surgical reconstruction where tissue is lifted from the patient's donor site and moved to his injured site with an intact blood supply (autologous muscle free flap). The current transfer surgery is complicated and involved with donor-site morbidity after tissue harvesting, and scant availability. We propose a robust engineered transplant performed by a novel reconstruction technique to overcome these disadvantages. The proposed transplant uses an alternative biomaterial implantation, offering the possibility to repair a full-thickness defect of the abdominal wall without the need to transfer tissue (skin+subcutis+fascia+muscle) from another site and minimal postoperative scarification (skin only). We name this technique ""an Engineered Autologous Vascularized Axial Flap"".  The key idea of this approach is the use of a polymeric scaffold upon which human cells will be seeded. The engineered tissue cultured in vitro will contain also a network of blood vessels. Then, this engineered construct will be implanted around large blood vessels adjacent to the injured site. Once highly vascularized, it will be possible to transfer the implanted engineered vascularized construct as a flap for covering the defects. Once developed, this autologous cost-effective engineered tissue product may be used in reconstructive surgery of the abdominal wall and breast (thousands of cases in the EU alone) which improves the patients’ quality of life and reduces surgical costs and risks. Here we describe a plan to develop this product by identifying the most cost-effective niche where we can go to market in. We plan to complete a se
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Memory and information processing in assemblies of neurons' (MIPAN) targeting Seventh Framework.

assistant: **Abstract**

Electrically excitable cells are present in many multicellular organisms, especially in brains of animals, but they are also present in lower animals lacking central nervous system as sponges or in animals having excitable epithelia, which can conduct signals (neuroid conduction). Conducted electrical events serve for translation of environmental parameters and cues, obtained via sensory systems, into biological information and processes. Living organism uses electric signal to encode sensory information and prepare it for further processing what results with a specific actions (behaviour) or with memory storage in cellular network. Understanding of physical basis of information processing in living organism is an important aim of the modern neuroscience. The most common way for uncovering the response organization is observation of cell cultures under particular conditions. Such conditions can refer to different type of environmental stimuli, like chemicals, temperature, light intensity including gravity. The adaptation of organisms to a certain gravitational conditions make their functioning working properly in symbiosis with the particular strength of gravitational acceleration on Earth. The question which arises, especially during the spatial exploration era in which we are living now, is what are the effects of gravitational changes on living organisms? Can they survive or adapt? And the most important question for neuroscientists: can the microgravity conditions affect the information processing by the animal brain and commanding units in plants? The study of this problem is of great importance when thinking about the long exposure to microgravity conditions during long spatial flights as well as during spatial colonisations. The main aim of the proposal  is the s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Advanced FOrging of an Optimized Turbine casing' (AFOOT) under Seventh Framework.

assistant: **Objectives**

The objective of this project is to determine and validate a robust set of forging and heat treatment parameters leading to the forging of a fan case for a geared turbofan demonstrator as part of the Sustainable and Green Engine (SAGE) platform by making the microstructure of ATI 718Plus stable against overaging effects occurring during long-term exposure at 700°C.This project represents the collaborative effort of an experienced company specialised in forging and ring-rolling of superalloys and a technological research centre with great competence in thermo-mechanical processes analysis and modelling.Development of an advanced predictive simulation modelling tool is a pre-requisite for the success of the project along with a thorough laboratory measurements campaign that will be performed to test the original material as well as the material overaged in conditions similar to those it should work at.The final outcome of the project will be the production of three fan cases whose design will be agreed upon with the topic manager, one of these cases will be cut up and properly examined in the lab while the other two will be delivered to the Topic Manager.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Original synthons for life sciences'.

assistant: **Concept**

Bioconversions using microorganisms or isolated enzymes are often used as chiral catalysts in preparative organic chemistry. They represent an alternative to the asymmetric catalysis. The use of whole cells is simpler for industrial purposes, however the enzyme production by a native microorganism is often low. The aim of the proposed project is to obtain recombinant enzymes for bio catalysis based applications. The first step will consist in isolating and cloning the genes that encode the enzymes to be used as biocatalysts. In the second step, the genes will be introduced and over-expressed in different hosts including bacteria, yeasts and fungi. Recombinant enzymes will be compared to the native ones in terms of their activities and other biochemical properties.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Diagnosis, prediction, communication and rehabilitation for patients with disorders of consciousness' in the context of a Horizon 2020 call.

assistant: **Objectives**

Recent work has shown that up to 42% of patients diagnosed with a disorder of consciousness (DOC) are misdiagnosed. New EEG system have revealed that some DOC patients can follow basic instructions that do not require any movement, such as imagining movement or counting vibrotactile pulses, which has even allowed them to answer YES/NO questions. This work has provided the foundations for new EEG-based solutions that could go even further – such as predicting clinical outcomes and even providing rehabilitation to facilitate cognitive and motor recovery and emergence into consciousness. The ComAlive project will develop new methods for combining EEG-based assessment and communication tools with prediction and rehab to provide new hope for these patients. The applicant is a practicing neurologist with excellent experience with DOC patients, but does not have training in business, EEG classification methods or software engineering. ComAlive is led by an R&D performing SME with a long history of real-time EEG and biomedical systems, and the other beneficiary is a hospital that is renowned for work with target patients. ComAlive includes extensive dissemination and communication activities to convey our project results to numerous audiences and supplement the ER’s training-by-research. This project will help prepare the ER for a high-impact career working across business, academic, and medical sectors while developing a new industrial system, methods and knowledge that could dramatically impact thousands of lives in the EU alone.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'MiniMo-Logistics application' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

MiniMo is an online service (SaaS) that fully automates the daily processes of the freight companies and helps in business cooperation between the market participants. The main feature of current solutions is to digitalize the paper-based daily routines, but our resulting product will fully automate the daily operations of the freight companies (receiving and processing assignments, optimal route planning and 3D optimization of the cargo with visualization on a smartphone, notifying the partners, managing the documentations, billing, etc.). The second objective is to create the means for the registered companies to contact each other, search for partners based on the relevant informations -working territory, capacity, special vehicle type-exchange data and give assignments to each other. In short term the users can reduce their total operation costs and time. In long term they can realize significant revenue growth owing to the extended partner network. The main target group of MiniMo are LTL (Less-Than-Truckload) carriers, especially in the groupage and the express segments in EU, as well as freight forwarders to search for business partners. During Phase 1 we will assess the necessary steps to assure the business and commercial success by observing the needs and processes of the market participants and establish the legal and business background of connecting the freight companies. MiniMo is currently on TRL-7, in Phase 2 we intend to develop the necessary modules - to reach TRL-9- and build a partner network. By using MiniMo CO2 emission can be reduced, the companies of the European Union will use a superior quality and more transparent shipping service, furthermore the competitiveness of the freight companies in the European Union will increase greatly.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'PROTECTION FROM VIRUSES WITH EPIDEMIC AND PANDEMIC DISEASE OUTBREAK POTENTIAL THROUGH DEVELOPMENT AND CLINICAL TESTING OF A NOVEL CAPSID VIRUS LIKE PARTICLE (CVLP) VACCINE'.

assistant: **Innovation**

The enormous health and economic impacts of epidemics and pandemics has become one of the defining public policy and health issues in Europe and throughout the world.  A new urgency is required to understand, rapidly respond to, and vaccinate against viruses with epidemic and pandemic potential. The major challenge for the modern vaccines is the induction of long-term protective immunity, as clearly demonstrated by fast waning of protection for current COVID-19 vaccines.  VICI-DISEASE is an ambitious project which combines existing cutting-edge expertise in a tried and tested consortium, with new advances in this critical field. The consortium’s main objective is to develop a vaccine candidate portfolio and perform a clinical proof-of-concept study, to enable stocks of vaccine candidates ready for further development (Phase 2&3) in case of pandemic outbreaks. The primary candidate will be Nipah virus (NiV), a high-mortality viral disease with no vaccines or treatments. Our vaccine is based on NiV G protein displayed on capsid Virus Like Particle (cVLP), enabled by adapting template processes from our recent COVID-19 vaccine (currently in Phase 3), and expected to provide best-in-class longevity as shown for COVID-19.The VICI-DISEASE consortium’s objective is to develop and perform a clinical proof-of-concept study for •a highly effective (>90% protection),•long-term protective (>2 years),•NiV virus cVLP vaccine,•by adapting template processes established for our COVID-19 vaccine (currently in Phase 3),•within 48 months in a Phase 1/2a clinical study, •to help protect medical workers and the public from future NiV and Hendra virus outbreaks,•and establish a pipeline of novel filovirus vaccines through pre-clinical proof-of-concept studies.We address the call topic by imp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Climate-related Beliefs and Low-Carbon Transition Dynamics' to be submitted under Horizon Europe.

assistant: **Abstract**

The transition to a low-carbon society, as mandated by the Paris Agreement and recent net-zero targets, requires a significant expansion and reallocation of physical investments. Investment choices crucially depend on firms expectations and beliefs. However, profound knowledge gaps exist regarding transition-related expectations: current modelling frameworks lack the capability to fully assess their impact on transition dynamics; empirical evidence on their distribution is scarce; and there is limited comprehension of their evolution drivers and how to align them effectively with climate targets. Misalignment of expectations can lead to failed or disorderly decarbonisation pathways. The BELIEFS project will lay the foundations of a novel analytical framework capable of shedding light on the complex interaction between firms beliefs, investment decision-making and climate policy strategies, so as to identify credible paths to a net-zero society. The project will deliver a methodological breakthrough by developing a dynamic transition model with a realistic representation of expectations as heterogeneous, evolving and interdependent. The design and calibration of the model will be informed by extensive data collection efforts, including original surveys and experiments. A large-scale survey of firms will produce the first comprehensive empirical assessment of transition-related expectations and their impact on economic decisions. The results of the project will be pivotal in identifying effective policy and institutional strategies to ensure alignment of beliefs, thereby enabling a swift and orderly decarbonisation process. Over the course of five years, BELIEFS aims to offer pioneering interdisciplinary contributions to advance our understanding of the macro-behavioural
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Development of Automated Handling Devices for the Flexible Transhipment of Goods' in the context of a Fourth Framework call.

assistant: **Objectives**

The handling and transhipment of goods is becoming increasingly automated allowing improvements to delivery times, logistics and cost. In certain strategic material handling sectors such as pallets and containers the use of standard products hinders the complete automation of distribution lines. Automated guided vehicles, palletised assembly and fully automated warehousing are in advanced stages of development and are used extensively in the manufacturing and distribution industry. To ensure their complete effectiveness, achieve a complete automated manufacturing and distribution cycle deficiencies need to be overcome and these issues addressed. - automated transfer and sorting of palletised goods into and out of storage loading bays, vehicle trailers, container wagons and aircraft. - the development of an intelligent pallet handling device. - the palletising or container handling of excessive or awkward loads.