RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'SIMULATOR OF BEHAVIOURAL ASPECTS FOR SAFER TRANSPORT' (SimuSafe) under Horizon 2020.

assistant: **Objectives**

Road transport is known to be the most dangerous of all transport modes and poses a major societal challenge for EU. It has been claimed that 90% of road-traffic crashes are caused by driver error, being a significant factor in traffic accidents. Improving road safety means understanding the individual and collective behaviour of actors involved (drivers, two wheelers, pedestrians) and their interaction between themselves and safety-related systems and services. The goal of SIMUSAFE (SIMUlator of Behavioural Aspects for SAFEr Transport) following the FESTA-V model methodology is to  develop realistic multi-agent behavioural models in a transit environment where researchers will be able to monitor and introduce changes in every aspect,  gathering data not available in real world conditions. Driving simulators of several vehicles (cars, motorcycles, bicycles) and Virtual Reality (for pedestrians) will be used to simulate test environments. This will also enable the evaluation of scenarios which are not possible even with naturalistic driving (dangerous conditions, multiple monitored actors in the same scene, under influence of substances). Data collected from simulations will be correlated with naturalistic driving tests, such that the simulation and model aspects are the closest possible to real world data. From the developed model and collected data, impacting factors causing an event (crash, near-collision, infractions) from the environment and road users will be identified and quantified. Such knowledge will be the base for the development of more effective and pro-active measures for the prevention and mitigation of such factors, with subsequent impact in the safety devices market, regulations and driver education.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Climatic Controls on Erosion Rates and  Relief of Mountain Belts' in the context of a Horizon 2020 call.

assistant: **Objectives**

Quantifying the feedbacks between tectonic processes in the lithosphere and climatic processes in the atmosphere is an overarching goal in Earth-Systems research, as it underpins our ability to differentiate natural from anthropogenic climate forcing. Long-term cooling during the Cenozoic has been linked to the growth of mountain belts, which enhanced erosion, chemical weathering, organic-carbon burial and drawdown of atmospheric CO2. Conversely, it has been proposed that the cooler and more variable climate of the late Cenozoic led to increased topographic relief and erosion. This latter coupling, however, has not been decisively demonstrated and remains highly controversial. Advancing our understanding of these couplings requires the development of tools that record erosion rates and relief changes with higher spatial and temporal resolution than the current state-of-the-art, and integrating the newly obtained data into next-generation numerical models that link observed erosion-rate and relief histories to potential driving mechanisms. The project COOLER shoulders this task. We will: (1) develop new high-resolution thermochronology by setting up a world-leading 4He/3He laboratory; (2) develop numerical modelling tools that incorporate the latest insights in kinetics of thermochronological systems and make sample-specific predictions; (3) couple these tools to glacial landscape-evolution models, enabling modelling of real landscapes with real thermochronology data as constraints; and (4) study potential feedbacks between glacial erosion and tectonic deformation in carefully selected field areas. The new high-resolution data will be integrated and extrapolated to quantitatively assess the impact of late Cenozoic climate change on erosion rates. Integration and analysis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'INterdiSciPlinarity and excellence for doctoral training of International REsearchers in Paris' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

United in a Community of Universities and Institutions, called “Université Sorbonne Paris Cité” (USPC), eight research universities  and five research organisations  located in Paris and its surroundings have decided to join their forces to build a world-class new type of university.Together they form a research-intensive university, with over 12000 professors and researchers including more than 6000 doctoral candidates. Each year, 1100 of these candidates defend their PhD thesis, corresponding to about 10% of the yearly new doctors cohort in France. These graduates are enrolled in one of the 31 doctoral schools affiliated to USPC and covering all fields of knowledge.INSPIRE will give more favourable working conditions to the selected candidates compared to French standards  while giving a better visibility. It thus expects to 1. Attract better candidates from a wider range of countries, raising globally the level of selection 2. Provide improved collaboration opportunities at international scale and with the non academic sector 3. Improve follow-up and mentoring conditions, notably through the presence of dedicated personnel.Within the five-year programme, INSPIRE aims to launch two calls to recruit 30 doctoral candidates for each call. They will be welcomed into the doctoral schools of its partner organisations thanks to the EU contribution and the USPC financial support. An independent, international committee will conduct the final selection.The participants will be provided with a three-year work contract for full-time research positions with additional access to dedicated funding for mobility and additional research expenses. All selected candidates will be offered dedicated housing through CROUS , another partner organisation of INSPIRE.Equal opportunity issues w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Origin, fate and function of wheat genes noncollinear with the other cereal genomes' in the context of a Seventh Framework call.

assistant: **Objectives**

In the framework of studies of the organization and evolution of the bread wheat genome, the host team has developed a large project aiming to characterize its largest chromosome, 3B, at the molecular level. A physical map of this giant chromosome (about the size of the soybean genome) was established in 2008 (Paux et al., 2008).  Recently, in a pilot study prior to the complete chromosome sequencing (3BSEQ project), the host group produced and analyzed precisely 18 Mb of contiguous sequences representing the first large sample sequences available for the hexaploid wheat genome. The results showed that about 50% of the genes and pseudogenes identified in wheat are not collinear with the other grass genomes raising several questions about their origin, fate and expression in the wheat genome.The objectives of this project are to select a number of non collinear genes in different structural contexts and (i) determine whether these genes originate from interchromosomal duplications of genes ancestrally present at distant loci, (ii) investigate the molecular mechanisms and evolutionary forces involved in the shuffling of the gene content, including transposable elements, and (iii) analyze their expression patterns relative to collinear genes through qRT-PCR experiments and analysis of RNA Seq data that will be produced in the 3BSEQ project on 15 different RNA samples. We will investigate the molecular evolution of their sequences in a hexaploid context where homoeologous and paralogous gene copies are maintained.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Models for operational reliability, integrity and availability of ship machinery systems' (MOSYS).

assistant: **Innovation**

Objectives and content MOSys aims to enhance the operational efficiency and profitability of ship plant systems through reliability, availability, maintainability (RAM) and cost analysis at ship design stage and implementation of Technical Asset Integrity Management (TAIM) technology during the rest of the ship life-cycle. In particular it seeks to harness the power of information technology in handling the lifecycle data, which is an essential requirement for achieving the above objectives. MOSys will achieve the above by developing and applying analysis techniques for:  RAM and maintenance cost analysis, based on use of ship machinery historical data, Failure Mode and Effect Analysis, criticality and risk analysis. This is primarily targeted at ship design phase.  Survey, Inspection and Repair (SIR) planning, for harmonisation of the logistic support for ship survey, inspection and repair in support of operational availability.  Technical asset management with asset's design, functional, and operational data capture and data analysis capability in support of RAM, SIR, cost analysis, and the life cycle tracking of the asset's conditions. This is targeted at ship operation phase. The above analysis modules will be supported by development of a common product data model for ship machinery systems, its application in the form of a comprehensive data repository and its standardisation within the ISO STEP framework. MOSys comprises 7 technical workpackages, which is defined in terms of work content, deliverables, partners responsible and schedule. The length of the project is 30 months. The MOSys consortium comprises 8 partners including 2 shipyards, 1 ship operator, 2 classification societies and 3 R & D institutes, in all from 4 European countries from south to north Euro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'StART: Science through ART', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

RN2019 Turkey is organized in Ankara by the Science and Society Center of Middle East Technical University (ODTÜ) to promote public recognition of “Science through ART – StART” and thus reveal the value of thinking outside the box. Art is utilized as an overarching theme because of its familiarity, which has great potential to break conceived barriers between science and society. The setting will be around five key areas each corresponding to a branch of art, namely drawing-painting, sculpture, architecture, music-dance, photography. Around each of these areas, we will host activities where invited science and art communicators will explain the many interactions between science and art through their works. That is, it will show how art can be inspired by science and vice-versa and how art and science can collaborate to better understand the world around us and increase our welfare. Our science communicators are mainly experienced researchers, but then again scientists and artists will be brought to the same platform since they both strive to see the world in new ways and communicate that vision; and thus “are more alike than different”. We aim to reach 10,000 on-site participants and 1,000,000 on-line or indirect beneficiaries regardless of their age and background. Nonetheless, special focus will be given to students ranging from pre-schoolers to high school students. The ultimate messages conveyed via StART will be “Science and art are indispensable to the human need of understanding the world around us.”, “A research career on science and art can be fun!”, and “Researchers are everywhere!”. Celebrating artistic creations and scientific discoveries can be a truly memorable experience for our beneficiaries. For younger audiences, the event may provide a life-changing m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Translating fundamental insights in podocyte metabolism and cell cycle regulation: development of a new treatment for Stopping crescentic Immune Glomerulonephritis'.

assistant: **Objectives**

Rapidly progressive glomerulonephritis (RPGN) is a syndrome of the kidney that is characterized by a rapid loss of renal function, with severe damage of glomeruli, the filtering units of the kidney through glomerular crescent formation (crescentshaped scars) seen on kidney biopsies. If left untreated, it rapidly progresses into acute renal failure and death within months. Regardless of the underlying cause, RPGN involves severe injury to the kidneys' glomeruli, with many of the glomeruli containing characteristic glomerular crescents. Currently RPGN is treated with broad-spectrum immunosuppression causing remission of the immune injury achieved in the majority of patients. Nevertheless, risk of end- stage renal failure at 5 years is still near 30 %, with a number of patients developing chronic kidney disease (CKD). Moreover, such treatments are associated with significant morbidity due to infections and malignancy. ERC-supported efforts in our lab have unravelled local mediators and transcription factors that critically control the tolerance of intrinsic glomerular cells to inflammatory insult. My team has shown that the PPARγ (peroxisome proliferatoractivated receptors gamma) pathway is instrumental in the protection of the inflammatory response during immunecomplex mediated RPGN, in large part through protection of kidney cells, named podocytes. We now plan to move forward to transform this finding from our TARGET-GLOMDIS ERC grant into a clinically effective innovative therapy. We expect to bring original therapeutic effect by preventing podocytes death and dysfunction in addition to promoting anti-inflammatory actions. The STOPIG project represents a unique opportunity to provide proof-of-concept for a new and cost-effective therapy for patients with RPGN based on s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'A european malaria vaccine development consortium: euromalvac 1' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

Pre-clinical development and testing with various adjuvants of candidate vaccines developed from Plasmodium falciparum Merozoite Surface Proteins and parasite-encoded antigens expressed on infected erythrocytes. Preparation of the Malaria Vaccine Testing Facility at Nijmegen University to carry out pre-clinical and clinical trials of malaria vaccines.Brief description: The consortium will co-ordinate work in 13 laboratories in 6 European countries on immunogen validation, vaccine design and synthesis, and pre-clinical and clinical testing of candidate malaria vaccines in a series of linked projects. The objectives are:Pre-clinical development and testing of Plasmodium falciparum Merozoite Surface Protein 1 (MSP-1) C-terminal-based vaccines with alum and new experimental adjuvants. Defining the binding sites and biological activities of specific antibodies, thus designing more effective vaccine constructs using immunological and biochemical assays correlated with immunity.N-terminal Block 2 sequences of MSP-1 will be inserted into Pichia pastoris vectors for expression at high yield, analysed for immunogenicity and reformulated in adjuvants for immunisation studies in Aotus monkeys.Parasites will be identified which express variants of the Plasmodium falciparum erythrocyte membrane protein-1 (PfEMP-1) that are commonly recognised by endemic sera. Objectives include : identifying cross-reactive epitopes, high-frequecy variants and mapping epitopes of PfEMP-1 ; inducing rodent and phage display antibodies against defined PfEMP-1 epitopes and determining whether specific human antibody responses to defined epitopes are associated with protection against disease.Carrying out codon re-engineering and scaled up P.pastoris expression of P.falciparum AMA-1 constructs to obtain p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Molecular Quantum Spintronics' (MoQuaS) targeting Seventh Framework.

assistant: **Abstract**

MoQuaS aims at developing devices and protocols to read out and process quantum information using individual molecular spins embedded in electronic circuits. To this end, prototypical hybrid nano-devices addressing single molecular spins will be designed and reliable methods for their realization will be developed. Core of such nano-architectures are magnetic molecules, specifically functionalized to graft electrodes, and exploited as spin (qu)bits. MoQuaS will design and realize the necessary platform for the read out and the manipulation of the electron and nuclear states of single molecules. Besides electromigrated junctions, contact electrodes based on carbon allotropes, including carbon nanotubes and graphene nano-ribbons will be developed. These will allow for interfacing the specially designed magnetic molecule to the outside world with an unprecedented flexibility, beyond what is possible with metallic electrodes. The resulting hybrid device will function either as molecular spin transistors (three terminal device) or as molecular spin valves by combining carbon based channels with molecular spin filters. The ultimate ambitious goal of MoQuaS is the implementation of quantum gates that will be achieved by using additional strip lines close to our hybrid nano-devices to carry out the spin manipulation. On the way to achieving this goal, a range of challenges will be met by implementing experiments and theoretical descriptions that will ascertain the fundamental mechanisms underlying the functioning of quantum molecular devices. In particular, the key processes of the electron and nuclear spin state preparation, manipulation and read out, spin injection and relaxation will be individually investigated in order to understand the basic mechanisms and then combine th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Smart Magnetic Solutions for Minimally Invasive Surgery'.

assistant: **Innovation**

The objective of this proposal is the reintegration of Dr. Pádraig Cantillon-Murphy, a research fellow at Harvard Medical School and MIT (Boston, USA), back to Europe, as Assistant Lecturer at Cork Institute of Technology (CIT). His reintegration will result in (i) research independence and increased European collaboration and funding support for Dr. Cantillon-Murphy, (ii) novel and high-impact research at CIT and (iii) sustained collaborations between Irish and EU engineers, physicians and surgeons. Dr. Cantillon-Murphy's principal research focus at CIT focus will be the development of smart magnetic solutions for minimally invasive surgery.Recent innovations in surgery, such as Natural Orifice Transluminal Endoscopic Surgery (NOTES), have the potential to result in scarless surgery, less anesthesia, shorter hospitalisation times, and lower healthcare costs for European citizens. Unlike traditional laparoscopy, which uses 3 or more transcutaneous ports of access, in NOTES, there is no transcutaneous port. Instead, an endoscope is passed though a natural orifice (e.g., mouth) to gain access to the peritoneal cavity via a “transluminal” incision through the stomach. However, one of the fundamental problems facing NOTES to create a secure, leak-free access port to target organs through the gastric wall. Dr. Cantillon-Murphy has developed a safe, simple and cost-effective solution using magnetic self-assembly to overcome this challenge.As faculty at Cork Institute of Technology (CIT) and in conjunction with the Medical Engineering Design and Innovation Centre (MEDIC) at CIT, Dr. Cantillon-Murphy will continue to pursue ground-breaking engineering solutions to NOTES and other applications of smart magnetic solutions in surgical procedures such as hernia repair, colorectal c