RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Production and removal of dissolved organic matter in contrasting oceanic environments' (PROCES) targeting Sixth Framework.

assistant: **Abstract**

Dissolved organic carbon (DOC) makes up the second largest of the bio-reactive pools of carbon in the ocean and plays a central role in the ocean carbon cycle. But little is known about what is this role, how is it realized and what are its mechanisms and controls. One of the major priorities is the identification of the truly important mechanisms of DOC production. Many publications present a large list of processes (phytoplankton exudation, herbivory, lysis, particle dissolution, etc.) but in truth we do not know which are significant when. A better understanding on the processes involved in the production and removal of DOC will allow for better predictions on DOC dynamics in the pelagic system.The main objective of the research activity presented by the candidate is to test the following hypothesis: There is a gradient of decreasing DOC bioreactivity from productive to oligotrophic waters which is related with different mechanisms of DOC production, and these differences have important consequences in th e bacterial community structure and in the carbon cycle. This Marie-Curie re-integration fellowship will allow the transfer of knowledge between the NIOZ (The Netherlands) and the University of Vigo, (Spain) and in addition, ensure a long lasting co-operation between both institutions.The introduction of the novel technique MICRO-CARD-FISH in the host group will increase the available tools for the study of the marine planktonic ecosystem and give the opportunity to the host group of taking a leading posit ion in this novel application in Spain. Furthermore, this project would imply the possibility for the candidate to get a stable research position at her country of origin."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Promoting the integration of continuous care in the hospital. The paIliative care mobile support team as a means to convey a philosophy of integrated and continuous care. Analysing medical practice and research in new integration strategies' in the context of a Fifth Framework call.

assistant: **Objectives**

The present tendency in Europe is to promote the creation of mobile support teams in Palliative care instead of residential palliative care units. Through the experience of the mobile support teams who are confronted with the full range of convictions held by persons in a hospital setting, the concept of Palliative Care/Terminal Care has been reinforced/strenghened/enhanced by the Continuous Care approach, which tends to articulate curative and palliative procedures rather than setting one form of therapy against the other.The project is directed towards lnter-and Pluri-disciplinary research among clinicians (responsible for mobile support teams), scientific experts (university institutes) and external consultants The aim is to clarify pedagogic training strategies in communication and ethics mediation in order to promote the integration of Continuous care for chronically ill patients in hospitals.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'AI-Enhanced fibre-Wireless Optical 6G network in support of connected mobility' (6G-EWOC), addressing dissemination and exploitation.

assistant: **Impact**

The 6G-EWOC project aims to contribute to the development of future 6G-AI based networks by ending with TRL-4-level developments on critical technologies and devices for expanding the reach of 6G, especially in high mobility scenarios. It is addressing Key Societal Value indicators (KVI) defined by the Work Programme and developing KV enablers such as services for coordination, precise positioning and localization, multi-agent supporting network architecture and joint communication and sensing. The three ambitions of 6G-EWOC focus on: AMB1, Optical Wireless Communications (OWC) for V2V and high-rate (Gb/s) V2I applications, chip-scale optical beamformers, and developing connected laser/radio detection, ranging, and communication (Lidar/Radar). AMB2, PIC and ASIC for tuneable transmitter and receiver concepts for fiber-based fronthaul supporting 50 Gbps and 100 Gbps per wavelength over DWDM fiber links and SDN-enabled photonic switching. AMB3 focuses on AI-assisted control and orchestration of resources for the multi-band, heterogeneous 6G-EWOC network concept and AI-based applications development for autonomous vehicles. Up to 17 KPIs are expected to be validated at three final demonstrations.In conclusion, 6G-EWOC search to develop an AI-enhanced fibre-wireless optical 6G network in support of connected mobility by creating a new access network for high mobility scenarios and expanding the reach of 6G through the integration of optical and wireless technologies, free space optics, and joint communication and sensing. It is supported by a fast, reconfigurable, highly dynamic, and customizable optical fiber fronthaul infrastructure, minimizing optoelectronic transitions by tuneable and programmable devices and low energy photonic switching of (packet/optical) spectrum an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Developing Molecular Medicines for Cancer in the Post-Genome Era' to be submitted under Sixth Framework.

assistant: **Abstract**

Cancer is a European public health problem of overwhelming human and economic significance. There is now unimproved molecular understanding of the key genetic, biochemical and cellular changes leading to cancer, insignificant part due to the efforts of diverse groups of world-class EU-based scientists. With the completion of the human genome sequence imminent, it is now timely to initiate a major European co-ordinated effort to translate fundamental scientific knowledge about cancer into safer, more effective therapies and improved early diagnosticprocedures. The cellular immortality enzyme telemetries (one of the most promising universal cancer markers) and associatedtelomere maintenance mechanisms represent novel anti-cancer targets of enormous therapeutic and diagnostic potential. In MOL CANCER MED, we have established a multinational EU transactional cancer research consortium, in which talented cancer geneticists and molecular biologists will interact with prominent haematologists, clinicians and pathologists to develop these exciting new cellular targets into measurable pre-clinical advances, within a 3.5-year time-frame.The Project has been structured into three, highly interactive Areas of Activity, involving the fundamental evaluation and pre-clinical validation of:(i) TELOMERASE as a target for cancer treatment and diagnosis based on new molecular knowledge about its expression and function,(ii) associated DOWNSTREAM TELOMERE MAINTENANCEMECHANISMS as additional targets for novel drug design, and(iii) new ANTICANCER DRUGS based on these targets. The Consortium will bring to bear diverse and complementary technological know-how of considerable power to deliver the above primary objectives. Effective management will maximize synergies across MOL CANCERMED in orde
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Adrenoceptors subtypes expression from human normal and pathological aging'.

assistant: **Objectives**

The present project is intended to analyse, by using autoradiographic and molecular biology procedures, the state of the expression of beta-adrenoreptor subtypes (beta1 and beta2) in the human brain, under both normal and pathological (Alzheimer's disease) aging. For such purposes, autopsies brain samples for a number of individuals without history of neuropsychiatric disease, and from a group of Alzheimer's disease brains will be used. Autoradiographic labelling will be carried out with (125I) cyanopindolol and molecular expression of the receptors will be performed by using the baculovirus expression system. We will be comparing the levels of expression and the autoradiographic densities of beta-adrenoceptors in several critical regions (cortex, hippocampus, striatum, midbrain) to clarify 1) whether there is a defined pattern of changes along the different decades of life; and 2) the type of modification of brain beta-adrenoceptors in Alzheimer's disease.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'High-temperature reactor components and systems'.

assistant: **Concept**

The work aims to consolidate the technological feasibility of innovative components and systems and a modem HTR with a direct cycle. It is focussed on -the innovative components (turbine, recuperator, magnetic bearings, rotating seal).Specifications will be defined. Design studies, validation of the concept proposals, experimental tests will performed;- the tribology. The experience feedback will be analysed. Tests will be performed in particular for the innovative sliding components;- the helium purification system. Recommendations concerning the helium impurities contents will be provided in accordance with the materials proposed for the innovative components.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Guiding Patients Anytime Everywhere' under Seventh Framework.

assistant: **Concept**

MobiGuide (MG) will develop a patient guidance system that integrates hospital and monitoring data into a Personal Health Record (PHR) accessible by patients and care providers and provide personalized secure clinical-guideline-based guidance also outside clinical environments. MG's ubiquity will be achieved by having a Decision Support System (DSS) at the back end, and on the front end by utilizing Body Area Network (BAN) technology and developing a coordinated light-weight DSS that can operate independently. Personalization will be achieved by considering patient preferences and context. Retrospective data analysis will be used to assess compliance and to indicate care pathways shown to be beneficial for certain patient context.MG will be validated on pre-selected clinical domains with intensive vs. sparse monitoring to demonstrate the generality of the design and assess functionality, feasibility, and impact.MG addresses EU priorities: increasing patient safety, ubiquitous secure access to health care, patient empowerment, developing a common platform for healthcare services, and competitiveness of Europe.The time is right for MG in view of Europe's vast interest in national PHRs and patient empowerment. MG will leverage this momentum to create a solution that goes beyond local proprietary and stand-alone EMR, DSS, and BAN.Our team includes complementary partners with diverse experience in: patient guideline-based DSS, focusing on reasoning with patient guideline intentions and temporal patterns, decision-theoretic models, knowledge-data integration, and information visualization Health BAN, telemedicine data analysis for diabetes, telemedicine applications for cardiology and expertise in large system integration to create the secure PHR.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Automatic radiosity simulation for complex and dynamic environments' to be submitted under Fourth Framework.

assistant: **Abstract**

The goal of this project is to overcome the current limitations to the use of realistic radiosity-based lighting simulation systems by making radiosity usable, thus opening the way to widespread usage of realistic digital mock-ups.Components of a robust and usable lighting simulation system will be developed, addressing:- Data acquisition and processing: tools will be provided to allow the use of unmodified end-user data bases as well as support for application-dependent output and results.- Treatment of complex models, allowing efficient lighting simulation of very large scenes.- Automatic control of the simulation eliminating the need for expert parameter selection.- Interactive manipulation of changing environments for which lighting is simulated.The development of a practical computer graphics lighting system will allow the use of realistic lighting simulation with digital mock-ups in a wide range of applications such as architecture, design, broadcasting, etc. Large-scale savings will result, first by shortening the development cycle in all domains of design using realistically lit digital mock-ups, and in the architectural field by allowing more energy-efficient designs thanks to the effective use of lighting simulation.New Products: the technology developed in ARCADE will be incorporated into a working prototype, and from there potentially integrated into the industrial partner's system. Dissemination: the methods and techniques developed will be made public through scientific and research publications as well as at trade fairs (e.g., Computer Graphics Expo, CeBIT). A web site containing information, technical reports and demonstrations will be made available.Realistic lighting simulation is an important emerging technology with many applications. By simulating s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'InP DHBT MMIC Technology for Millimeter-Wave Power Applications', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

With the advent of smart phones, tablets and connected cameras, mobile data traffic is growing at a very fast pace. The capacity of mobile backhaul network must be increased to deal with this data explosion. In that respect there is at present an increased interest in exploiting the millimeter-wave frequency range (30-300 GHz) for wireless backhauling. The progress in semiconductor device technology, in particular compound semiconductor transistors such as High Electron Mobility Transistor (HEMT) and Heterojunction Bipolar Transistor (HBT) devices enables the development of wireless communication circuits operating at frequencies well above 100 GHz. The main bottleneck in these mm-wave wireless communication systems today is the power amplifier (PA) which sets the limit on the available transmission range. The overall objective of the ""IN-POWER"" project will be to develop an InP HBT technology optimized for millimeter-wave power applications. The development of the InP DHBT technology will be accompanied by the MMIC (Monolitic Microwave Integrated Circuits) implementation of PA's targeting emerging applications at E-band (71-76 and 81-86 GHz) and higher millimeter-wave frequencies.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Spatially explicit material footprints: fine-scale assessment of Europe’s global environmental and social impacts' (FINEPRINT).

assistant: **Concept**

In the era of globalisation, supply chains are increasingly organised on the international level, thus disconnecting final consumption from the location of material extraction and related environmental and social impacts. Reducing these global impacts – or footprints – of European consumption is a major societal and scientific challenge. Methods to assess teleconnections between distant places of raw material extraction and consumption along global supply chains have improved significantly, with multi-regional input-output (MRIO) analysis being the most prominent method applied. However, the limited spatial resolution of MRIO models distorts footprint calculations, as specific properties of raw materials as well as impacts of extraction can vary significantly within production countries. I therefore propose a new method for the calculation of fine-scale material consumption footprints. It will encompass (1) a spatial assessment of global material extraction on a high-resolution grid and (2) a detailed physical model that tracks raw materials from the location of extraction via international transport facilities to processing industries in importing countries. Integrating this very detailed spatial information with a MRIO model will enable the first fine-scale assessment of European countries’ material footprints, overcoming prevailing aggregation errors in footprint indicators. Furthermore, I will investigate environmental and social impacts related to material footprints through linking the spatially explicit multi-regional material flow model with datasets on impacts related to raw material extraction, such as increasing water scarcity, deforestation and mining conflicts. This project will not only lift the accuracy of footprint models to a new level, but will also op
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Central roles of mycobacterial type VII secretion systems in intra- and inter-kingdom warfare'.

assistant: **Objectives**

Bacteria interact with their environment via specialised secretion systems that deliver proteins outside of the cell. Due to a bias in research efforts, for many years such systems were assumed to be unique to Gram-negative bacteria. A major exception is the type VII secretion system (T7SS), which is widespread in Gram-positive bacteria and actinobacteria, including the important human pathogen Mycobacterium tuberculosis. The T7SS is a complex secretion apparatus that exports folded proteins and even protein complexes. While secreted substrates are well-known for being crucial players in host-pathogen interactions, our recent data indicate that specific substrates of the relevant opportunistic pathogen Mycobacterium abscessus and the fish pathogen Mycobacterium marinum are also involved in interbacterial antagonism. This makes T7SSs important factors to understand microbial interactions, also for the understudied part of the microbial world. While the mechanism of secretion via T7SSs remains little understood, our preliminary data show that not only their roles but also their substrates are more diverse than thus far thought. Here, we unite leading experts in microbiology, structural biology, cell biology, and biophysics to spearhead research on mycobacterial T7SSs and their roles in both interbacterial and host-pathogen interactions. In this unique consortium, we will (i) define the full trans-envelope T7SS by atomic force microscopy and cryo-electron microscopy, (ii) study the mechanism of transport by creating translocation intermediates, (iii) expand the set of T7SS substrates by extensive proteomics and bioinformatics analysis, and (iv) visualise the role of T7SS in bacterial warfare and host-pathogen interactions using microfluidics, innovative lung-on-a-chip infe