RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Effective green financial policies for the low-carbon transition' (GREENFIN).

assistant: **Concept**

Mitigating dangerous climate change requires a fundamental transition of global economies. This transition calls for an annual investment of 2–4 trillion USD, which is a multiple of current climate investment. Accordingly, the EU and many countries are enacting green financial policies, intervening in the financial sector to improve financing conditions for low-carbon technologies. Examples include green state investment banks, carbon disclosure requirements, and changes to lending regulations. However, the effect of these financial policies on investments in non-financial sectors such as energy, transport, or building is largely unknown. More specifically, we lack insights on how different low-carbon technologies require different types of finance (such as public vs. private finance, corporate vs. project finance, or equity vs. debt). Hence, it remains unclear how to make best use of such policies to fill the climate finance gap. By bridging disciplines and using novel data, GREENFIN will lead to a breakthrough in our understanding of the effects of financial policies on the low-carbon transition in non-financial sectors, and thereby lay the foundations for a new interdisciplinary field of financial policy analysis. First, combining theory from technology innovation studies and financial economics, I will derive how technology-inherent characteristics predict the demand for different types of finance. Second, using policy analysis tools and novel machine learning-based methods, I will analyze the effects of green financial policies on the supply of various types of finance. Third, combining these insights I will deliver specific recommendations for designing more effective green financial policies in the EU and beyond. By including financial policies in policy mix anal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'IP for Innovation' (IP4INNO).

assistant: **Innovation**

The main aim of ip4inno is to increase understanding and usage of intellectual property (IP) by SMEs (which currently lack know-how regarding IP management), with a view to increasing innovation and competitiveness in line with the Lisbon goals. Ip4inno proposes to address this by disseminating across several European countries the most relevant and useful information and training packages on protecting and exploiting IP, and IP management (with the main focus on patents).Ip4inno is aimed principally at SM Es and their advisers; researchers; and students. Once their specific needs have been verified, information and training resources will be pooled  and developed and finally disseminated electronically via a specially designed web portal; and by the delivery of around 10 different seminars to _train the trainers. This training will then be disseminated to many end-users in each country as a pilot scheme to get feedback, with a view to improving it. The aim is for the project to continue, develop and expand following the initial 2-year period. A management committee will ensure high-quality standards, which will also be checked via evaluation questionnaires at all levels. A final, independent evaluation report will assess the success of the project and recommend improvements.The objectives of ip4inno directly contribute to those of the Work Programme, in particular through: setting up the basis of a European innovation system by networking players, promoting cooperation, breaking down barriers and encouraging transnational learning; investigating and testing new approaches, promoting entrepreneurial innovation; and offering services that need to be provided on a European scale. In line with the Specific Programme, ip4inno will improve _the knowledge, understanding and c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Phenotyping the Biologic Diversity of Endothelial Cells' (ENDOTHELIOPATHY).

assistant: **Concept**

Background: The microvasculature of elderly population is frequently affected by disease states such as diabetes and ischemia. Our group has set up new gene transfer approaches for the prevention and cure of diabetic microangiopathy. For translating these pre-clinical successes into clinical deliverables, it is necessary to gain a deeper understanding of downstream pathways and effector proteins. Serial analysis of gene expression (SAGE) and proteomics represent potent instruments to achieve the goal. Alth ough these methodologies are becoming accessible to individual investigators, the range of options can be bewildering for the uninitiated so as to require transfer of knowledge interventions across European laboratories. Aim: The present project is aimed t o characterize the proteomic diversity of diabetic endothelial cells. In particular, the proposal focuses on the identification of RNA transcripts or proteins contributing to the premature senescence of vascular endothelium in diabetic animal models and th en correct these defects by appropriate gene therapy approaches. Significance of Transfer of Knowledge: The host institution has an established experience in angiogenesis-related diseases, which will allow to peak up instantaneous advantage of new instrume nts for proteomic analysis. Absorbing competence in this field will put our laboratory -located in a less favoured region with the highest incidence of diabetes- in the conditions to provide the first description of proteomic diversity of diabetic microvas culature, thereby facilitating the introduction of new mechanistic therapeutic approaches.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The Tsar's Famines: Economic policy and famine in late Imperial Russia, 1891-1911' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

The turn of the nineteenth and twentieth century witnessed transformational changes in the Russian economy, marked by rapid integration into global markets and state-led industrialization. In the same period, Russian society faced dramatic crises, the most devastating of which were a series of famines that cost millions of lives. Both dimensions of development have been subject to extensive study, but the fundamental disconnect between these historiographies leaves a yawning knowledge gap. TsarsFAMINE will conduct a systematic examination of famine intensity and famine relief strategies in regions of the Russian Empire between 1891 and 1911, constructing the first comprehensive database of demographic and agricultural statistics at the county level. Using this novel and unique database, a multi-variate analysis will identify the causes of famine including the potentially significant role of trade policy. The project will then combine quantitative and qualitative sources and analytical methods to examine the effectiveness of different famine-relief strategies adopted in different provinces of Russia over the twenty-year period. TsarsFAMINE advance the state-of-the-art in several ways. It will improve our understanding of the deeper socio-economic outcomes of the state policies that propelled the industrialization of late imperial Russia. It will contribute to the broader literature on the effectiveness of famine relief exploiting a richly documented historical case study with significant variation in famine intensity and famine relief policies. The project promises important insights for development experts and international institutions that engage in the study of modern famines and engage in global famine relief. TsarsFAMINE will be a major accelerator in the career of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Electronic and magnetic properties of correlated electron systems: from cuprates to fullerides'.

assistant: **Objectives**

The main focus is a study of the magnetic and electronic properties of correlated systems including Fullerides and cuprates through a unique combination of nuclear magnetic resonance and Muon resonance techniques for which the applicant will be trained
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Substrate import at work: single-molecule studies of ABC transporters' (SM-IMPORT) under Horizon 2020.

assistant: **Objectives**

ABC (ATP Binding Cassette) transporters represent the most abundant and diverse family of transport proteins known that play crucial roles in numerous cellular processes. Despite their importance, all proposed molecular models for transport are based on indirect evidence due to the inability of classical biophysical and biochemical techniques to directly visualize dynamic structural changes. To solve this problem, I suggest a novel approach that can decipher the molecular mechanisms of transport, with the ultimate goal to use this knowledge against pathogenic bacteria, for treatment of ABC-related diseases or multi-drug resistance of cancer cells.I propose to use single-molecule fluorescence microscopy for the study of conformational states of an ABC model system in vitro, and thus to observe directly how elementary transport steps are coordinated. This will open up a virtually unexplored biophysical research area and provide a detailed understanding of the molecular mechanisms of ABC transporters. The key questions of this proposal are:Aim 1: What is the mechanism of substrate binding in ABC transporters? The conformational equilibrium (open vs. closed state) of ABC-associated substrate-binding proteins will be studied to understand the molecular mechanism of binding, i.e., induced fit vs. conformational selection.Aim 2: What are relevant conformational states and changes for substrate translocation? The time- and length-scales of conformational changes in transmembrane and nucleotide binding domains as well as interactions with other domains will be characterized using the osmoregulator OpuA as a model system.Aim 3: How are substrate binding, energy utilization and translocation coordinated in ABC transporters? Finally, a complete model of transport will be developed
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Aging-related changes in brain activation and deactivation during cognition: novel insights into the physiology of the human mind from simultaneous PET-fMRI imaging' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

There is no doubt that functional magnetic resonance imaging (fMRI) has led to a breakthrough in our ability to measure how the complexities of the mind are rooted in biology. However, deactivation of certain brain areas during cognitive control and increased activation of prefrontal areas in aging are two examples of consistently found patterns of fMRI activation that have had a large impact on the study of the human mind, but that prompt major questions of interpretation. The physiological basis of the fMRI signal reflects interplay between hemodynamics and metabolic demands that vary across the brain, as well as between different tasks and individuals, and cannot be resolved by fMRI alone. To be able to use non-invasive imaging to distinguish a normally aging brain from one that is in the pre-clinical stages of disease, it is important to understand the neurobiological basis of these functional brain changes. Positron emission tomography (PET) is a molecular imaging method that is able to monitor brain glucose metabolism, which stems primarily from synaptic activity and is invariant to changes in blood flow. Studies that have made use of the complementary information gained from fMRI and PET to investigate human brain function have had to rely on sequential scans, and correlation of the signals from both modalities between individuals. The investigation of within-person switches between different mental states with complementary modalities is only made possible by the recent development of a hybrid PET-MR system, which, for the first time, allows simultaneous assessment of fMRI signal, blood flow and PET glucose metabolism during cognitive task performance. The proposal is structured in three work packages that include PET-fMRI scans in 30 healthy younger and 40 olde
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Conference on youth and human values""' under Fifth Framework.

assistant: **Concept**

The International Society for Human Values will organise an international conference on YOUTH AND HUMAN VALUES" from 15 to 18 October 2002 at the Geneva International Conference Centre (CICG), Geneva, Switzerland. 200 delegates including life scientists, social scientists, educators, philosophers, administrators, youth leaders and representatives of civil society will discussant debate issues involving, inter alias, Biotechnology, Health and Ageing, Bioethics, Information Technology, Poverty and Health, Education and Human Values. Plenary sessions and workshops are intended to contribute to better understanding of science, foster dialogue between life scientists and civil society, especially the youth, to gauge public attitudes to life science research and its applications and, to provide guidelines to include life science aspects in educational programmes and curricula."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'PCP for Water Smart Metering' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

European Water utilities environment is embedded in a context dealing with global issues such as water scarcity and technical-economic issues such as infrastructure aging. Management of drinking water supply is facing key challenges partly related to traditional water meter, such as managing capital and operational costs; water loss (also known as non-revenue water) due to leaks and other system failures; and water scarcity/conservation. The core of the solution lies in the renewed access and use of accurate data that Smart Water Metering can provide to decrease operating costs, identify performance issues, improve customer service and better prioritize infrastructure investments.SMART.MET strongly paves the way to a more efficient management providing for example automatic reading of the household meters and billing, real time assessment of water balance for leak detection, identification of abnormal behaviors and awareness-raising, ability to identify user-meters defaults.However, the lack of common European standards and lack of “open technological platforms” combined to the high transaction cost on the demand side create a lock-in situation in the market and determine a situation of long-term dependency of water operators on technology providers. This determines high average operating costs for water operators and users, as well as collective inefficiency related to the multiplication of different proprietary solutions on the offer side. The objective of the proposal is thus to drive the development of new technologies to manage smart metering data collection and management, driven by a group of 7 water utilities through a joint Pre Commercial Procurement (PCP).They are supported by 6 expert organizations for assessing the technologies, implement the new procurement
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Development of mesosphere in-situ measurement tools: Atmosphere Analyser' (DAA) targeting Horizon 2020.

assistant: **Abstract**

The Mesosphere and Lower Thermosphere (MLT) are the most poorly known stages of the Earth’s atmosphere. Knowledgeof the events on the MLT region are linked to better prediction of events on surface weather and thus improve weatherforecasting, reduce insurance costs via better data and predictions, deliver fresh data for climate disasters preventionD-Orbit Atmosphere Analyser (DAA) is an innovative system based on nanosatellite technology that promises to deliver insitu real-time data on any geographical area of the MLT. DAA exploits recent advancement in space technology to provideservices for Earth entities and commercial businesses.Our goal is to provide to commercial businesses and research entities fast, low cost, reliable and “fresh” data related to ourplanet, its atmosphere and the near space environment, via innovative systems independent from geographical locationsand launchers’ cost. DAA offers real-time, geo-localized and fresh MLT data for catastrophe prevention and especially for insurance companies, improving their forecasts reliability, reducing their financial risk and thus increasing their margin on insurance products sold. DAA is scalable and easily upgradable to extend the sensors capabilities and thus enter in different “big data” market.This project will contribute to the generation of Climate Data Records being a support feature to efforts undertaken by ESAunder the LEIT Space programme. Furthermore, DAA is a disruptive and competitive solution that will seize European andglobal business opportunities by transferring this advanced and low cost technology from the space industry to non-spaceareas.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Efficient & Selective Ion Pumps based on Ratchet Mechanisms' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

I propose a novel membrane-like device that utilizes a ratchet mechanism to drive ions selectively up a concentration gradient. This device can serve as a building block for an efficient, ion selective separations technology.Ion selective separation with membrane-based processes may advance dramatically technologies for water treatment, resource extraction from sea water, ion specific sensors and many other applications. Moreover, since about 10-15% of the global energy consumption is used for chemical separations, a high efficiency, membrane-based ion separation processes can reduce greenhouse gas emissions significantly. However, membrane-based ion selective separation is a longstanding unmet challenge in science and engineering. Although conventional membrane-based separation is extremely efficient in unselective separation processes such as reverse osmosis water desalination, membrane-based processes showed limited success in ion specific separations. Furthermore, the need for a molecular level control of the membrane properties, limits the scalability of most of the membrane-based ion selective separation techniques that are currently being studied.Our proposed device, the ratchet-based ion pump, is driven with a ratchet mechanism which utilizes modulations of a spatially asymmetric electric field to induce a non-zero net ion flux up a concentration gradient. We will utilize a fundamental ratchet process in which the ratchet input signal drives particles with the same charge but different transport properties in opposite directions, to design highly selective, fit-to-purpose, and real-time controlled ion separation systems thereby bypassing the limitations faced by current technologies.In this research we will combine theory, simulation and experiment to improve ou