RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Morphodynamic of the Swash zone: Experimental and numerical modelling', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

One of the major shortcomings of Coastal Sediment Transport Models is the poor definition of the shoreward boundary of the fluid domain or, more specifically, of the Swash Zone (SZ). Following this assumption, the present project aims to provide both major advances in the knowledge of SZ processes and major improvements in the modelling capability of the SZ dynamics. Focus will, first, be in increasing the current knowledge of SZ dynamics and in implementing some of the recent advances in a new Lagrangian, intra-wave model, especially designed for the SZ flows. The model is such to take into account the time history of water particles when predicting the sediment transport at a given location. Previous studies suggest that Lagrangian methods offer many advantages in representing the complex processes occurring in the SZ. The next task to be undertaken in the course of the project is the inclusion of dynamical SZ mechanisms (evolving at the intra-wave time scale) in wave-averaged nearshore circulation models by using new Shoreline Boundary Conditions (SBCs). This fundamental piece of modelling has been the object of various recent implementation attempts made within the international research community. Experimental measurements of SZ flows, sediment concentration and intra-wave information of bed changes, outcome of an ongoing experimental EU project in which both the candidate and the host institution are involved, will be made available to help the modelling. Further experiments, aimed to validate the codes to be implemented, are also planned to be carried out at the host institution. The proposing research team, having available both extensive experience in SZ measurement and leading capabilities in SZ numerical modelling, is ideally positioned for implementing the c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'A new concept in zeolite catalysis: Morphology induced shape selectivity'.

assistant: **Concept**

Zeolites are crystalline aluminosilicates and have been used as catalysts within refining and hydrocarbon conversion processes since the 1960s. In addition to possessing strong Brønsted acidity, zeolites are microporous materials, having regular pores channels and cavities of molecular dimensions. These materials therefore possess shape selectivity for chemical reactions. Nevertheless, insufficiently shape selective catalyst, leading to rapid deactivation and unselective production, is a major obstacle for improved and new zeolite based industrial processes.The scientific vision of ZeoMorph is to establish a new concept within shape selective zeolite catalysis - morphology induced shape selectivity, wherein the shape selective properties will be determined primarily by particle morphology and not framework topology. The concept will be demonstrated by synthesis of series of catalysts having systematic morphological properties, which will be examined as catalysts in industrially relevant hydrocarbon conversion processes.This ambitious vision will be met by bringing together leading European groups within physical and inorganic chemistry. The catalysis research group at the University of Oslo (UiO) in Norway and Danish industrial partner Haldor Topsøe (HTAS) based in Lyngby near Copenhagen are full network participants. Research groups at the University of Torino (UniTo, Italy) and Aarhus (AU, Denmark) with unique competence within spectroscopy and computational chemistry will be associated partners in the project.The ZeoMorph early stage researchers will spend 50% of their time in the industrial sector at HTAS and the remaining time will be divided between extended stays at the partner academic host UiO and 3 month stays at the associated partners. This network will educ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Relearning Perception Action In Rehabilitation from a Systems perspective' (REPAIRS) targeting Horizon 2020.

assistant: **Abstract**

Movement disorders related to perception and action, such as stroke, significantly impair functioning in daily living, severely impacting the life of affected individuals and having a huge economic impact. Although rehabilitation practice aims to restore functional ability through re-learning perception-action couplings, it leads to marginal improvements of daily functioning at best. Here it is argued that to improve effectiveness of rehabilitation a systems approach should be adopted to understand processes underlying perception-action disorders. A systems approach takes into account nonlinear interactions between components, enabling to explain for instance why patients do not respond stereotypical to rehabilitation training. REPAIRS (RE-learning Perception-Action In Rehabilitation from a Systems perspective) is a unique and timely training-through-research school, aiming to improve rehabilitation effectiveness. REPAIRS starts from systems-based fundamental knowledge on learning perception-action couplings to build applications to rehabilitation, while exploiting recent technology advancements. This research school provides the required critical mass of top-level researchers connecting European academic, clinical and technology experts to train the next generation of researchers and entrepreneurs in this perspective. REPAIRS studies interaction between four levels of the perception-action cycle: brain, muscles & joints, agent-environment and social, which is integrated with requirements on translation from clinical, technology and philosophical domains. The focus on interactions between levels and domains naturally ensures an interdisciplinary and intersectoral training. Integrating this with a high-level training of transferrable skills, dissemination and communicati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Regularity properties, definability and combinatorics on the real line.' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

This proposed research is in mathematical logic and foundations of mathematics, more specifically in set theory. It is motivated by the interplay between regularity properties and definability for subsets of real numbers. By ""regularity properties"" we are referring to certain desirable properties of sets, and by ""definability"" to the logical description of such sets, in the sense of Descriptive Set Theory.The study of such questions goes back to classical issues in topology, analysis and related fields of mathematics, raised by the great pioneers of abstract mathematics of the late 19th and early 20th century, such as Georg Cantor, Emile Borel, Henri Lebesgue and others. These mathematicians were faced with seemingly insurmountable challenges which could only be resolved later with the advent of logical and meta-mathematical methods, developed by Kurt Gödel in 1938 and by Paul Cohen in 1964.Since that time, the study of Regularity Properties has continued to hold a central position in the foundations of mathematics. Many mathematicians and logicians of high status and prestige have contributed to this area, among them W. Hugh Woodin (winner of the Hausdorff Medal 2013), Stevo Todorčević (winner of the CRM-Fields-PIMS prize 2012) and Saharon Shelah (winner of numerous awards, among them the Erdös Prize 1977 and the Karp Prize 1983).We propose to contribute to this line of research in a number of interrelated directions, such as: studying new regularity properties (relevant to other fields of mathematics), developing abstract frameworks for such properties, studying higher complexity classes, and generalising results to spaces other than the classical real numbers. Several technical results involving the method of ""forcing"" needed to construct models of set theory,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Entrepreneurship Laboratory for Eastern European Regions', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

ENLARGE is a non take up accompanying measure that addresses the IST Action line II.1.5 by promoting broad adoption of eCommerce and eWork in regional and sectoral settings of Eastern Europe and Balkan countries. ENLARGE will develop a methodology for devising and putting into action an eBusiness strategy, customised in nation specific and local characteristics of the participating countries. The project will also produce training courses that target SMEs managers and aim at stimulating their exploitation of eBusiness opportunities. ENLARGE results will be tested in Enlargement countries, where eCommerce deployment is still low. ENLARGE aims to support economic integration of Enlargement countries by providing an e-strategy framework that will stimulate SMEs participation into global digital economyOBJECTIVESThe project aims to promote the integration of candidate enlargement countries through the application of a methodology for devising and putting into action eBusiness strategy in SMEs and a series of executive education programs customized for SME managers in Eastern Europe.The project objectives are:1. To promote awareness of eBusiness/eCommerce opportunities and challenges in Eastern Europe at a micro level by addressing business managers directly;2. To engage in initiatives that transfer practical knowledge;3. To show how knowledge can be converted into action;4. To focus on management action rather than generic awareness;5. To demonstrate how eBusiness decisions are taken in practice;6. To generate learning from experience;7. To address local conditions and requirements.DESCRIPTION OF WORKThe project develops and delivers customized executive development training programs. Additionally, the project generates further awareness among SME executives in Eastern Euro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Reinforcing the Scientific Excellence of Selcuk University in Engineered Surfaces and Films for Emerging Technologies' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Surface chemistry and sub-surface phenomena have been played a crucial role in developing a host of modern technologies and represent a driving-force of current interdisciplinary approaches. The control of the surface, structure and morphology through advanced surface engineering and well controlled fabrication has rapidly expanded in line with the demand for emerging applications. The aim of the project is to enhance SU’s scientific excellence and innovation capacity in engineered surfaces and films for emerging technologies to the European level, by working with leading European institutes of proven capability to innovate and deliver technology to industry. Excellence will be achieved by embedding University’s activities in a network of excellence provided by our twinning partners and will allow SU access to the latest know-how and facilities, improve our R&D innovation capacity, strengthen research management, administration skills, train SU’s academics and ESRs. To achieve this aim, a 3 year project will be built upon the existing strong research and innovation interaction with our twinning partners, Advanced Materials and BioEngineering Research (AMBER) Centre hosted in Trinity College of Dublin (TCD) (Ireland) and Fondazione Bruno Kessler (FBK), Trento, Italy.EngSurf-Twin will boost SU’s scientific excellence and innovation capacity in this critical interdisciplinary field by providing training activities for ESRs spanning nanofabrication, characterisation, materials and interfaces, advanced sensing concepts, smart materials and structural environment, nano-devices and microsystems. By linking with internationally-leading research institutions EngSurf-Twin will enhance the S&T capacity, raise the research profile of SU, increase research excellence, enhanced the r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Carbanions as Functional Groups and Building Blocks for Novel Reagents, Catalysts and Materials'.

assistant: **Objectives**

Carbanionic compounds such as organolithium or Grignard reagents are important organometallic reagents and commonly used in organic synthesis for difficult deprotonation or C-C bond formation reactions. Due to the strongly polarized metal carbon bond these reagents are usually highly reactive and sensitive towards air and moisture and thus must be handled under strictly anhydrous conditions. Owing to this intrinsic reactivity, carbanionic compounds are usually only prepared in situ and scarcely applied beyond their classical use as strong bases or alkylation reagents. Free carbanions without stabilizing metal-carbon inter¬action are usually even more reactive but can be isolated when being stabilized by electron withdrawing groups. These naked carbanions are isoelectronic to simple amines. Yet, whereas amines are applied in various fields of chemistry not only as bases but also as versatile building blocks and functional groups, applications of free carbanions are very limited. This project will change the perspective on carbanionic compounds. By careful molecular design the reactivity of carbanions will be controlled to enable their use as broadly applicable building blocks and functional groups. Experimental and computational methods will provide a fundamental understanding of the electronic structure and its influencing factors, thus allowing for a systematic use of the anionic nature and donor capacity of carbanions to reach properties and reactivities, which are not accessible via conventional strategies. Thus, we will provide a new toolbox for the design of smart anionic reagents and catalysts. The power of this concept will be demonstrated by applying carbanions in different research directions ranging from the stabilization of main group species with unusual ele
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Advancing Mountable Endoscopic Cap for Precision Oesophageal Mucosal Resurfacing with Non-Thermal Ablation'.

assistant: **Concept**

Treatments that minimize adverse effects on deep tissues may be critical for successful therapy in a superficial pre-cancerous condition such as Barrett's oesophagus. Although endoscopic therapeutic interventions efficiently eradicate superficial abnormal tissues in the oesophagus, the main challenge with their current deployments is that the therapy depth typically has a more profound thermal injury than the target layer. The project's objective is to develop a novel endoscopic cap that provides local non-thermal ablation to the superficial layers of the target oesophageal wall with sufficient depth for mucosal resurfacing. A design compatible with endoscopes will enable navigation, diagnosis, and ablation together—all-in-one.In support of the objective, the research programme is split into the following indicative specific aims based on EU MDR (2017/745) ISO (13485) & TSE (60601) regulations. Aim-1: Development of numerical modelling to mimic non-thermal ablation dynamics of the endo-cap. Aim-2: Optimization of numerical modelling with computational accuracy by in-vitro studies. Aim-3: Establishing the quality control process. Aim-4: Configuration of the endo-cap's original design in a CAD program and then realize the design with an optically transparent material containing electrodes for a porcine animal model, in vivo. Aim-5: Integration of the endo-cap with an endoscopy system to construct an endoscope equipped with the endo-cap for preclinical trials. Aim-6: Investigating the functional feasibility of an endoscope system in a GI endoscopy simulator. Aim-7: Validation of the system's oesophageal mucosal resurfacing performance in an in vivo porcine model, including tissue samples for histology examination at different time points.The action results are thought to m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Modulation of the Notch receptor activity through the regulation of the epithelial apical-basal polarity in Drosophila melanogaster' (2007-2013) targeting Seventh Framework.

assistant: **Abstract**

Several lines of evidence suggest an interplay between apical-basal polarity (ABP) and Notch (N) signaling in epithelia. Available data indicate that modulation of N signaling can occur through both direct regulation of the activity and mislocalization of either the receptor or the ligand. The purpose of this project is to understand how N activity can be modulated by differential regulation of apical-basal components or, in general, subcellular domains. A genetic screen among genes involved in ABP, ranging from regulators of vesicular trafficking or protein sorting to polarity regulators themselves, will help us identify the components underlying this modulation. Further genetic analysis together with molecular biology and biochemistry studies will help understand the molecular mechanisms of N activity modulation by ABP. Both ABP regulators and N pathway members have been shown to be involved in crucial events during development and tissue homeostasis, such as control of epithelial integrity and cell division, that, when distorted, can lead to tissue overgrowth and eventually cancer. Nevertheless, the molecular mechanisms underlying these processes are very poorly understood. This project will help shed light on these mechanisms.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Novel gut-stable peptides and drug-delivery systems - possible treatment for IBD' under Horizon Europe.

assistant: **Concept**

Inflammatory bowel diseases (IBD) affect more than 2 million residents in Europe. Currently, there is no cure for IBD, and treatment focuses on alleviating symptoms. Injured/compromised mucosal barrier and GI biofilms are common pathophysiological deviations in IBD. The overall aim of this project is to develop gut-stable peptides effective against biofilms, peptides suitable for wound-healing treatment, and nanocarrier systems for targeted delivery. In particular, I will focus on developing new antibiofilm peptides, based on the existent cathelicidins, and also develop GI wound-healing peptides based on the trefoil factor family (TFF). Cathelicidins and TFF peptides occur naturally in humans, and defects in these response systems can lead to GI diseases. Hence, in this project I aim to: (i) design, synthesize and characterise novel gut-stable antibiofilm and wound-healing peptides, and (ii) develop nanoparticle drug-delivery systems for their targeted application. Based on peptidomimetic synthesis, I will produce peptides containing unnatural amino acids, loop and helix mimetics, and also retroinverso analogues. Chitosan-coated liposomal and silica nanoparticles will be used for targeted colon treatment, as multifunctional systems: nanocarriers protect the peptides, chitosan enables mucoadhesive release, and chitosan has also beneficial anti-inflammatory, wound-healing and antimicrobial effects on its own. High regioselectivity and limited off-target effects can be achieved by using gut-stable peptides targeting local sites of inflammation, compromised gut epithelium and biofilms, since they are too large to cross the gut barrier. Orally administered peptide drugs targeting colonic tissues represent a highly innovative and safe route in treating GI disorders.


**Keywo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Production of monoxide nano-powders of stable quality using a technical scale plasma synthesis process' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

The aim of the project is to produce non-oxide nano-powders of stable quality using a technical scale plasma synthesis process.This goal must be reached using know-how and technology transfer and by the implementation of advanced quality management techniques. The quality of the two types of powder chosen in the project will be demonstrated using prototypes.The ability to produce nano-powders having constant quality on a technical scale is the basis for the growing industrial use of promising nano-materials. The reduced wear and friction as well as other improve properties of the materials offer substantial benefits to several industry sectors.The interdisciplinary co-operation of the partners (powder producers, materials producers and material users) is the basis for the success of the project.