RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Stochastic Model Predictive Control, Energy Efficient Building Control, Smart Grid' (SMPCBCSG), addressing dissemination and exploitation.

assistant: **Impact**

Energy efficient building control can have a major impact on reducing the overall energy consumption since a large part of today's energy is consumedin buildings. The use of model predictive control (MPC) together with weather and occupancy predictions is a promising approach to realize significantenergy savings.The control of power grids is of major concern due to the increasing number of renewable energy sources which introduce additional variability. This can bemitigated against by making use of additional storage, e.g. by leveraging the thermal energy storage of buildings.These areas demand for advanced and novel control solutions, which can handle uncertainty, large-scale systems, distributed systems, and predictions of the future system behavior. The aim is to use recent advances in random convex programming, couple these to MPC and develop a novel stochastic MPC formulation that is tractable for large-scale systems.The key objectives of this project are:- Development of stochastic MPC strategies, which address the above challenges.- Development, implementation and testing of a new energy efficient control strategy for buildings on a test-bed at UC Berkeley.- Formulation of tractable dynamic power flow problems involving a stochastic formulation and including buildings as additional storage in the formulation.The project is designed as a structured two-year program, where the first year is carried out at the University of California, Berkeley under supervision of Prof. Tomlin and the second year is carried out at the Swiss Federal Institute of Technology Zurich under supervision of Prof. Morari.The project will provide the fellow with excellent opportunities to further develop her competences and skills. Furthermore, it will strengthen the collaboration and establ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Herramienta Integrada Toatal de Optimizacion' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

HITO is a general purpose tool for advanced control developed under the ESPRIT PACE initiative. There is a wide variety of tools on the market for advanced process control: identifiers, predictive control, adaptive control, adaptive-predictive control, expert systems, etc. but the complexity of selecting, integrating and connecting them with the control systems existing on the plant is such that only large and sophisticated organisations can profit from the advantages of advanced control. HITO integrates all of these existing technologies within a single environment friendly and easily connected to the existing system, and therefore, puts the advantages of advanced control within reach of small and medium firms. The technologies integrated within HITO are: dynamic process identification and signal analysis, predictive control, process simulation, expert systems tool and economic optimisation. It also includes already interfaces with some of the popular basic control systems. It is modular and open in order to be adjusted to the requirements of each application. Tools with this scope do not exist presently on the market. HITO has demonstrated its functionality, but this functionality is not considered sufficient for the beginning of the exploitation phase of the product. The main objective at present is its launching to the market with full guarantee and the preparation of an exploitation plan, for which it is necessary a rigorous program of validation tests and its corresponding adjustment in function of the obtained results. To carry out this validation, an agreement has been established between the companies INITEC (Spain), as principal contractor, Sociedad General Azucarera de Espana (SGAE) as technological support and GENERALE SUCRIERE (France) and AUGHINISH ALUMINA
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'How Birth Control Pills Affect the Female Brain' (BECONTRA), addressing dissemination and exploitation.

assistant: **Impact**

Birth control pills have been on the market for almost 60 years now and are used by almost 200 million women worldwide. Particularly, the use of birth control pills increases among adolescents. However, the effects of birth control pills on the brain have widely been ignored. It was my own research that found the first indication that birth control pills affect female brain structure and masculinize female brain function. Furthermore, I recently obtained evidence that these changes are strongly dependent on the type of synthetic hormone contained in birth control pills and might affect some brain areas, like the hippocampus, beyond the duration of contraceptive treatment. This poses the question, whether effects of birth control pills on the brain are fully reversible after women stop taking the pill, especially if pill use occurs during sensitive periods of brain development, like in adolescents. Previous studies suffer from small sample sizes and insufficient study designs. Importantly, they compare women on birth control pills to naturally cycling women (cross-sectional designs) rather than following the same women from before she starts taking the pill through the first months of her pill use and vice versa (longitudinal designs). Accordingly they may be confounded by sampling bias.Therefore the general aims of this proposal are (A) to study the effects of birth control pills on the brain – for the first time – systematically in a longitudinal design, and (B) to address whether the effects of birth control pills on the brain are fully reversible. I seek to link changes in the brain to changes in behaviour, and address whether different types of pills cause different effects. Most importantly, a specific focus will lie on teen use of birth control pills. In order to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Engineered Humanized Spinal Cord Construct for Advancing Health and Disease Research'.

assistant: **Concept**

Current in vitro models of the central nervous system (CNS) fail to recapitulate its intricate structure and function, posing significant challenges to advancing our understanding of neurodevelopmental, neurological, and neurodegenerative diseases. Current 2D cultures, 3D organoids and animal models are limited for studying both healthy and pathological states, slowing progress in neuroscience. New CNS models must integrate advanced biofabrication, innovative bioinks, and cellular engineering to mimic the complex structure, vascular networks, and multi-cellular integration of the CNS.Recent progress in bioprinting and tissue engineering enable the fabrication of complex structures, while bioinks and biomaterials provide optimal cellular environments for differentiation, and functional integration. Additionally, state-of-the-art imaging and omic technologies have improved the ability to capture detailed structural and cellular data, ensuring that CNS models mimic native CNS architecture and dynamics.SPINECRAFT will develop a 4D functional human spinal cord construct (hSCC) that replicates the structural complexity and dynamic functionality of the human spinal cord (hSC). Our approach will use advanced imaging and computational techniques to map the architecture and cell distribution of the hSC. Using this information, we will generate human neural and vascular cells alongside bioinks designed to mimic the native microenvironment. We will then print a high-fidelity hSCC, validate it with imaging, multi-omics, and electrophysiology, and integrate patient-specific iPSCs to model amyotrophic lateral sclerosis (ALS) to recapitulate disease-specific microenvironments.SPINECRAFT represents a paradigm shift in CNS research, providing a versatile platform to study hSC biology, ne
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Biomolecular regulation with interlocked cyclic oligonucleotides'.

assistant: **Objectives**

Developing molecules that display protein-like functions and efficiently operate in complex biological environments, e.g. cells, is a grand challenge in chemistry. The aim of BioRIcON is to develop a novel class of biohybrid interlocked molecules (BIMs) that mirrors the function of proteins and enables precise biomolecular regulation. Despite the advances of interlocked molecules, often compared to biological motors, their use in cellular or in vivo settings pales compared to their natural counterparts. BioRIcON comprises an entirely new concept in artificial biology and biomolecular control by yielding BIMs that contain dynamic components ultimately designed to efficiently actuate in cells with high spatio-temporal resolution. I will develop molecular switches and motors using small cyclic oligonucleotides (cONs) that will be mechanically bound – like links in a chain - to other biomolecules to regulate their function. The resulting BIMs merge the best of two worlds: i) the programmability and biocompatibility features of oligonucleotides, and ii) the robustness and scalable production of synthetic mechanically interlocked systems.The goals of BioRIcON include: i) developing BIM-based shuttles and motors that can operate effectively in biological environments, integrate, and react to cellular cues and signaling; ii) exploring mechanical interlocking for reversible molecular display and protection against degradation; iii) implementing BIMs in biomolecular regulation, focused on reversible oligonucleotide-based therapies.BioRIcON will significantly advance the toolbox of biomimetic systems and enable their integration in processes such as gene regulation and protein expression. BIMs use mechanical interlocking to reversibly protect and control biomolecular function in a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Musculo-skeletal injury reduction tools for health and safety' (MIRTH) targeting Fifth Framework.

assistant: **Abstract**

The aims of this project are to develop new, and improve existing, Musculo-skeletal Injury Reduction Tools for Health and safety (MIRTHs), and to improve their effectiveness, ergonomics quality, and ease of application in the design and development of products, workplaces and work systems. This includes MIRTH software, MIRTH manufacturer-independent algorithms for software manufacturers, MIRTH programs customised for SMEs, training and education on health & safety at work, and ergonomics and MIRTH tools available on a local and tele basis. The project will assure ergonomic suitability and added value for three main purposes improved health and safety of workers and product users, improved design and development processes of new products and workplaces/work systems, and support of the training of engineers, health & safety personnel, and ergonomists.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The International Post doc Fellowship Programme in Plant Sciences' to be submitted under Seventh Framework.

assistant: **Abstract**

PLANT FELLOWS is a new international Post doc fellowship programme in the field of plant sciences. PLANT FELLOWS will be managed by the Zurich-Basel Plant Science Center, the sole beneficiary of the COFUND action, drawing from 10 years of expansion and success in fellowship management and higher educational establishments.PLANT FELLOWS will be open to applicants from all over the world. 15 European and 7 international universities and research institutes and 3 industry partners have been pre-defined as host organisations on the basis of their excellence in higher education and plant research.PLANT FELLOWS will offer 74 new Post doc fellowships spread between three different schemes (incoming, outgoing and reintegration) and a structured training programme for experienced researchers, including workshops, dedicated training in complementary skills and industrial placements. Unique in its kind, the fellows of the programme have the opportunity to obtain a Certificate in Plant Research and Development. PLANT FELLOWS thus aims at establishing a Training and Qualification Framework in the area of life-long learning/vocational training which complements the present postdoctoral training in plant sciences with an international competitive dimension.PLANT FELLOWS aims at delivering trained people who can enable the EU to respond to its changing needs in, for example, food production, plant-based energy production, sustainable land use, agricultural developments, and environment protection. By promoting a high level of intersectorial interactions and transnational mobility, the fellows will have access to frontiers expertise in plant research and state-of-the-art facilities in a way that is not possible within any existing or national programme. The mobility activities and adjus
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Paleoproductivity and sedimentary fluxes on the Portuguese margin - a sedimentological input' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

Research objectives and content The main objective of the applicant 6 months period-stay at the Marine Geology Department of the Geological and Mining Institute (IGM-DGM), is the sharing of knowledge acquired for the last years among leading work teams (Cambridge IOS-DL, SOC) with the host institution paleoceanography group, lead by Dr. Fatima Abrantes. Particular objectives are as follows: Collaboration and co-supervision of projects focused on the Iberian Margin, area of specialization of the applicant during her PhD thesis, at the Univ. of Cambridge. Several papers recently published synthesise this work (see CV). Shared work and published joined papers prove the previous strait collaboration, still in course, between the applicant and the DGM (see CV). The presently applied grant would provide an opportunity to collaborate on an ongoing project as well as consolidate future projects. Laboratory training and advise in techniques related to grain size analysis for young researchers of the Host Institution. Scientific support in the selection of quality and organization of abstracts into subjects for the VI International Paleoceanography Conference, a prestigious multi-disciplinary meeting for the paleoceanographers community, to be hold in Lisbon in 1998 by the host department. The applicant belongs to the conference executive committee. Training content (objective, benefit and expected impact) Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Estimates of ground motion and hazard assessment through earthquake scenarios' (EGMOES).

assistant: **Innovation**

This proposal brings some basic contributions both to fundamental (physics of he earthquake generation process and seismic wave propagation) and to the applied (estimates of seismic input time histories for civil engineering purposes) science. In particular, the estimate of the earthquake related ground motion is a basic requirement for the construction of damage scenarios, for the effective assessment of seismic hazard and or the proper re-evaluation, presently in progress, of the existing building codes such as EUROCODE8. The trainees will master a state-of-the-art procedure for the optimal fruition of the existing relevant geo technical and geological data, for the deterministic ground motion modelling, and or the construction at seismic hazard scenarios. Further improvements and applications to this procedure are planned, in particular to any high-risk (e.g. nuclear power plant or dam locations, urban environments etc.) area of EU member states and elsewhere.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Neurodevelopmental disorders in premature infants caused by thyroid hormone insufficiency - molecular basis for diagnosis and therapy'.

assistant: **Concept**

Transient hypothyroxinaemia in prefer infants are associated with laterneurodevelopmental deficits in motor and cognitive function. The overarching goal of our research programme is to determine the molecular basis of transient pothyroxinaemia of prefer infants and to use this information to drive the development of novel preventive and/or therapeutic strategies for these widespread and potentially debilitating handicaps of brain function. Here we have assembled an international and multidisciplinary research consortium, which is in a unique position to achieve this goal, with a combination of clinical, scientific, and manufacturing expertise. We plan to study at the molecular level the major pathways of iodothyronine metabolism and iodine supply in early human life and in experimental models, and then translate this information into new products for detecting, preventing and correcting transient thyroid dysfunction of prematurely.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'RondelO - the first medical stopcock designed for sequential intraveneous infusion of incompatible drugs'.

assistant: **Objectives**

CYTO365 is developing RondeO® - a revolutionary medical stopcock to be used with intravenous drug administration sets (IV sets). RondelO® is the first medical device that allows for a sequential intravenous administration of up to 6 drugs with the neutral saline in between the drugs. RondelO® aids the nurse to administer drugs to the patient safely and correctly, by letting only one drug pass at a time. It solves the problem of serious side effects caused by drug incompatibility by eliminating human error and unwanted parallel infusion and thereby increases patient safety. Moreover, RondelO® is easy to use (minimal training required), safe for the user (Closed System Valve (CSV) minimizes hazardous drug expose for the nurse), customizable (different configurations with 2, 4 or 6 drug inlets with or without CSV available) and time-efficient (all drugs are connected to IV set at the beginning of the procedure).


**Keywords:** intravenous medical device,intravenous infusion set (IV set),sequential drug infusion,drug incompatibility