RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Livelihoods in the Platform Economy Ecosystem' (LivePlatforms).

assistant: **Concept**

Work mediated by digital platforms – where the platform brokers labour relationships between worker and client, consumer, or other end user – has become an increasing feature of the employment landscape across Europe. Consequently, understanding the nature of this work has become an urgent need. The LivePlatforms project will develop and test a method for gathering qualitative data on the wide ecosystem that comprises platform work as a lived experience across a national context and critically appraise the mediating roles of the actors involved in this economy. The over-arching aim of this project is to develop a holistic understanding of platform labour by generating, applying, and evaluating a methodological framework that will enable the interrogation of the forces comprising the experience of this work, including and especially those of the lifeworld. By combining methodological concepts from Social Reproduction Theory, Actor Network Theory, and the Livelihoods Approach, it proposes the Platform Livelihoods Ecosystem Approach (PLEA). This methodology approaches platform work as an ecosystem of interacting actors, systems, and processes that manifest across a broad range of labour forms and which interconnect in the pursuit of a livelihood by workers. The objectives are to develop, test, and evaluate this method; to generate a complex understanding of the actors, systems, and processes that define a national platform economy and how they interact to produce labour outcomes; and to critically assess the mediating agency of these actors. The outcomes will be a rich, critical, empirical understanding of the lived experience of platform work and a tested method for qualitatively evaluating platform work on a national scale and with the necessary scope for holistic unders
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Nanomaterials via Gas-Phase Synthesis: A Design-Oriented Modelling and Engineering Approach', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The main objective of the NanoDome project is to develop a robust model-based design and engineering toolkit for the detailed prediction of complex nanomaterial structures produced in a commercially-relevant generic bottom-up Gas-Phase (GP) synthesis process, to improve the control of the nanomaterial production and the industrially-scalable GP synthesis process for more accurate final product properties (e.g. particle size, surface area, structure, chemical composition, morphology and functionalization coatings) and provide potential end-users with a validated tool based on scientific principles that enables predictive design of novel nanomaterials and novel GP production routes thereby shortening their development process. This will be pursued by combining computational modelling, software development and systematic validation activities at lab- and industrial-scale in a three-year project. Existing meso-scale nanomaterial GP synthesis modelling approaches (Lagrangian and stochastic) will be extended and integrated with continuum-scale reactor models to provide a fully functional single discrete mesoscopic model for the evolution of the nanoparticle population inside a control volume as a function of time, together with detailed description of nanoparticle composition and internal structure (e.g. core-shell, multi-layer, radially-dependent composition), particle interaction, coagulation and morphology. Industrial and lab-scale validation will focus on a set of target materials of great impact for the EU, using technologies currently at TRL4-6. The work proposed in the NanoDome project addresses the aforementioned challenges by delivering a modelling and analysis tool for the detailed prediction of complex nanomaterial structures formation in a single-step and industri
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Acceleration of Innovative ideas to Market' in the context of a Fifth Framework call.

assistant: **Objectives**

The project goal will be to develop a system to support the collection of all useful knowledge throughout the extended enterprise for new and existing process and product developments, and to develop this knowledge into a means of fostering industrial innovations. Innovation by combining the ideas and feedback from all parts of the product life cycle, including customer interaction with existing products and new product ideas, and including customer service and field engineers, including suppliers, and including pooling of knowledge between multiple sites. Innovation is a critical factor in the success of industrial companies. Europe suffers from a recognised gap compared with its major competitors, because it is less able to translate knowledge into innovation.Objectives:The objectives areTo develop a means of stimulating the creation of innovative ideas and collecting them from people involved with the products and processes. Specifically to increase the number of innovative suggestions, concepts and new designs by 50% in all user companies.· To develop a way of processing these ideas and storing them into a structured knowledge repository. To ensure that all useful knowledge (innovative information) is saved;To develop a means of analysing innovative knowledge to determine which is useful, and which is not. That is, to enable the viability of ideas to be assessed;To develop the best means of delivering the innovative ideas to the product and process designers for maximum effect.Work description:The proposed work and the distribution of tasks within this project have been designed to ensure achievement of the objectives of the project and a minimisation of some of the main risks:There are two types of activities:Support activities: The are two support workpackages (Ma
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Pricing carbon with a dedicated currency to empower economic agents' in the context of a Horizon 2020 call.

assistant: **Objectives**

450 is the SME operating and promoting a digital platform for the management of the CO2 digital currency (CO2s) based on the CO2 reductions achieved by a CO2Account owner. A CO2Account is held in the platform to register the CO2 consumption, to calculate the yearly reduction, and to provide the relevant credit, expressed in units of CO2. CO2 is the alternative digital currency which rewards the account owner by the verified reduction of 1 kg of CO2 emissions through the reduced use of fossil fuel in heating and/or transport.CO2s can be credited to, and debited from (notably with CO2Cards -payment card, or with a mobile App) the account. The CO2/€ exchange rate prices carbon.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Integral leadership and communication in non-profit organisations' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Leadership and communication process become increasingly important in organisations. Specific developments like budget cutting, deregulation, marketisation or privatisation of non-profit services and changing public policies exert an increasing influence particularly on non-profit organisations. A large amount of studies has shown the impact of both leading and communicating in this context. However there exists no comprehensive integral model and corresponding empirical research on the linkage between leadership and communication in non-profit organisations. The objective of this project is to construct such a model and to investigate empirically the relationship between leadership and communication in non-profit organisations in Germany and Switzerland.  To achieve this objective, the project will:  (1) start from existing theories with an inter- and transdisciplinary approach, developing an integral framework and research design as well methodology, rendering describable key variables, and moderating factors as well as problem areas and barriers of leadership and communication practices. (2) deduce hypotheses from theoretical propositions and the integral framework, considering subjective, inter-subjective and objective levels, that are covering specifically the interconnected processes of intentional, emotional and behavioural as well as socio-cultural and structural domains of leadership and communication. (3) test the hypotheses and validity of the integral model empirically in concrete context of German and Swiss non-profit organisation, including a comparative analysis. (4) derive theoretical and practical implications as well as societal relevant policies for an effective leadership and communication as well as corresponding organisational learning. The implica
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Development for a paint application system for lifting platforms' under Fifth Framework.

assistant: **Concept**

The objective of the project is the development of a paint application system for lifting platforms (PASLIP=Paint Application System for Lifting Platforms) for use in ambient outdoor and indoor conditions. By developing such a system, it will be possible to avoid the adverse effects associated with paint over spray and to improve the safety of the working environment with significant economic and environmental benefits. Beside the environmental benefits, such a system will raise productivity in outdoor paint application significantly. The PASLIP system will be controlled by software which analyses the structure to be painted, allowing the most effective painting path, control of the paint coverage etc. The data necessary can be obtained by means of an interface between existing CAD and CIM systems and the system's control unit.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'DIGITALISATION FOR AGROECOLOGY' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

D4AgEcol will show the potentials of digitalisation as enabler for agroecological farming systems in Europe based on available knowledge and actors' and stakeholders' co-innovation capacity . Partners from seven countries across a wide spectrum of pedoclimatic zones in Europe will assemble a holistic evaluation of digital tools and technologies. This will be based on indicators for agroecology, economic considerations and investigations about perceived benefits for user and stakeholder. Drivers, barriers and risks of digital technologies for a transformation towards agroecology will be identified. The results of this analysis will feed in national and European roadmaps for agroecology, indicating the need for adjusted policies and a technology research and innovation agenda.


**Keywords:** Precision Farming, Agricultural Economics, Adoption of Innovations
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Analysis of the kinetochore architecture and dynamics using a mass spectrometry based integrative structural approach' to be submitted under Seventh Framework.

assistant: **Abstract**

A mechanistic understanding of a living cell requires the characterization of the architecture and dynamic assembly of its macromolecular complexes. The proposed project describes a novel integrative approach to determine the topology of protein networks and higher order assemblies using chemical crosslinking, state of the art mass spectrometry (MS) and cryo-electron tomography (cryo-ET). This MS based strategy will enable the high-throughput detection and integration of structural data of biological systems. As a promising target we have chosen a giant key cell division structure, the human kinetochore, which is crucial for faithful chromosome segregation during cell division. Up to now, a comprehensive understanding of its cell cycle-regulated assembly and the nature of interactions between its protein components remain elusive. To investigate the architecture of the kinetochore we propose to apply a novel MS based crosslinking strategy that allows monitoring of protein interfaces at primary structure level. We plan to combine this technology with cryo-ET of the native kinetochore structure and of affinity-purified kinetochore complexes. Based on the spatial restraints obtained by MS, subunits can be fitted into electron density maps with high confidence, which will facilitate the generation of a 3D topological map of the entire kinetochore. Currently, there is no mechanistic understanding of the temporal dynamics of kinetochore protein assembly/disassembly which presumably involves cell cycle-controlled synthesis and degradation, as well as post-translational cues. To measure alterations in protein levels and phosphorylation status, we will investigate purified subcomplexes or whole cell lysates by quantitative targeted MS methods pioneered by the host institution. T
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Macaronesia's Researchers' Night' under Horizon 2020.

assistant: **Concept**

Macaronesia is a biogeographical region of five archipelagos in the Atlantic Ocean of which four are inhabited: Azores (Portugal), Canarias (Spain), Madeira (Portugal) and Cape Verde (Cape Verde). These islands share common geographical traits and challenges, and have undergone a similar history since the beginning of the 15th century when they were discovered by Portuguese and Spanish sailors. Once major strategic outposts now they are the Outermost Regions of the EU (except Cape Verde, which declared its independence from Portugal in 1975). The population of Macaronesia is around 3 million inhabitants, corresponding to the size of a smaller EU country. The overall objective of this project is to organise a shared Researchers’ Night for the Macaronesia Region connecting the population of these remote islands under the umbrella of the universal language of science. MacaroNight II aims at creating overall public awareness of science, research and innovation, especially in areas where the Region has outstanding performance even by international comparison. The main theme for MacaroNight 2020 will be a “Window to the Atlantic” creating visibility the work of scientists who are in the frontline of the battle fought against global environmental challenges working in some of the most vulnerable ecosystems of the world. By increasing visibility and international recognition of the work of scientists from the region MacaroNight II will have long-lasting beneficial impacts that could extend beyond the immediate objectives of the project.


**Keywords:** Outermost Regions
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Role of pancreatic beta-cell regeneration in the pathofisiology and treatment of insulin resistance and type 2 diabetes' (BCELL-T2D).

assistant: **Innovation**

Diabetes is a devastating illness declared by the World Health Organization as the XXI century epidemic. It is urgent to define the factors contributing to diabetes onset and severity, and to identify new potential therapies to prevent and treat diabetes and its complications. Type 2 diabetes develops through a multi-stage process. The body becomes unable to use insulin effectively and the pancreatic beta cells try to compensate producing more insulin, a condition known as insulin resistance. Eventually the beta cells become exhausted and cannot produce enough insulin to overcome insulin resistance. At this point, this condition frequently progresses to diabetes. Diabetes develops after a substantial decrease in the number of beta cells (increase in cell death/decrease in proliferation and neogenesis) and/or the impairment of insulin secretion needed to maintain euglycemia. The molecular mechanisms by which beta cells fail to compensate for insulin resistance remain elusive. The aims are: 1) Identification of the molecular mechanisms that lead to impaired beta cell proliferation in the pathophysiology of type 2 diabetes. 2) Therapeutic role of beta-cell proliferation in the treatment of type 2 diabetes. To address aim 1, db/db mice deficient for the leptin receptor on a C57BLKS/J background (a genetic model of obesity that develops diabetes) will be used. The techniques chosen for this aim include: proliferation studies; identification and quantification of cell cycle control proteins (western-blot, RT-PCR and immunofluorescence); techniques to study glucose/insulin homeostasis (glucose/insulin levels, glucose tolerance test and insulin tolerance test). To address aim 2, adenoviral vectors that contain cDNA of cell cycle activators (cyclin C, cyclin D1, D2, D3, cyclin E
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Controlling Activity of Lysogenic Phages by Small Molecule Inducers and Dysregulators', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The human microbiome has been increasingly in the focus of research for its importance in human health and disease. Yet, the viruses (phages) infecting these microbiota have gained much less attention. The majority of phages reside integrated in the genomes of their microbial hosts as so called lysogenic prophages. Often, these prophages encode important toxins and other virulence related factors that, while they are beneficial to their microbial hosts, may be detrimental for the infected human. Prophages can be induced under certain conditions to resume a lytic lifestyle resulting in the production of virus particles and often in the destruction of the host cell. Frequently, however, phage induction also leads to increased production of virulence factors. In this project, we aim to uncover small molecules modulating phage induction. We will explore to what extent microbial metabolites of human microbiota act as native triggers or inhibitors of phage induction and shape the complex interspecies interactions in the microbiome. The corresponding phage inducing or dysregulating metabolites will be isolated to elucidate their chemical structure and unveil their molecular targets. We will develop chemical tools to dissect and interrogate the responsible mechanisms and finally develop customized synthetic modulators that allow us to achieve control over the activity of phage-microbe systems with specific medical relevance. The integrated approach of the CAPSID project will provide first comprehensive insights into the chemistry of microbe-phage interactions and allow to assess its role for infectious diseases and its potential for customized treatment of microbial pathogens.


**Keywords:** Microbial metabolites, natural product analysis, chemical probes, phage induction