RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'European Research Area on Societal Aspects of Genomics' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

The field of genomics has an increasing impact on today?s society. It is vital to conduct research on the ethical, legal and social aspects (ELSA) of this field in order to come to terms with this impact and increase awareness of genomics and its implications in the public. The ERA-NET CA project ERASAGE - European Research Area on Societal Aspects of Genomics- includes the important players in funding of ELSA research regarding Genomics, and emphasizes the importance of co-ordination and co-operation on the level of programme management. Scope Eight national funding agencies with specific funding allocated to the field of ELSA of genomics, (Netherlands, United Kingdom, Austria, Norway, Finland, Germany (2) and Canada), as well as three funding agencies with a specific interest in this field (Israel (2) and Switzerland) are joining forces in ERA-SAGE. The proposed ERA-NET network will be open for other European partners with developing ELSA programmes and will act as a learning platform for these funding agencies. Programmes to increase understanding of all aspects of genomics and biotechnology are critical. This process and experience could also be useful for and expandable to other new technologies. Objectives Today, the programmes in the partnering countries are very divergent and often small in scale. The partners have committed to an ambitious ERA-NET programme to achieve synergy and convergence, to enhance the quality and the quantity of this research and to move on to a durable multi-national strategic partnership. Work programme The partners identified four interdisciplinary domains to enhance the network with increasing levels of co-ordination: 1. Synergy building: information exchange 2. Needs assessment: define common strategic issues 3. Capacity building: im
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'IDENTIFYING AND CHARACTERIZING REGULATORS OF PRIMORDIAL VASCULAR ADVENTITIA DEVELOPMENT, ORGANIZATION AND FUNCTION' (2007-2013).

assistant: **Innovation**

Vascular development and function are complex processes of utmost importance to the organism involving numerous steps and cell types. One of the tissues participating in these processes is the vascular adventitia, the outermost layer of the vessel, mainly composed of connective tissue. Recently, with the association of the adventitia to a growing number of diseases, its activities have become slowly uncovered and shown to participate in a number of developmental and homeostatic processes. Despite this, the processes that regulate the development, organization and function of the primordial embryonic adventitia are still unknown.This proposal is aimed at addressing the mechanisms and key genes regulating primordial adventitia development, organization and function. It concentrates on uncovering the molecular mechanisms underlying the activities of Tbx5, the transcription factor associated with Holt Oram Syndrome. Significantly, Tbx5 deletion during limb outgrowth leads to novel phenotypes whereby vessels form but are then ruptured as a result of an abnormal primordial adventitia organization. We have uncovered two putative target genes mediating its activities – the tumor suppressor Lysyl oxidase and the oncogene beta-Catenin. We will take advantage of the developing limb as a proven model system that allows easy access and manipulations to address the different developmental and functional aspects of the proposal. Taken together, the proposed experiments will uncover and characterize novel processes required for the development and function of the adventitia. Due to the unique properties of the adventitia, this research will set a basis for testing the relationship between a tissue's organization and function. It will enhance the understanding of the pathways that parti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Stereocontrolled synthesis of naturally occurring cladiellin oxacycles' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Research objectives and content The cladiellin and eunicellin oxacycles, together with eleutherobin, constitute a family of potential antitumour medium ring ether natural products. The research programme involves the following objectives: (i) Petasis methylenation of vinyl-substituted cyclic carbonates, followed by (3.3) sigmatropic rearrangement, to give medium ring lactones. (ii) Elaboration of 9-membered lactones to 2,9-divinyl substituted oxonins for ring closing methathesis to eleutherobin analogues.  (iii) Synthesis of a naturally occurring cladiellane by intramolecular Diels-Alder cycloaddition of a 2,9-disubstituted oxonin. (iv) Evaluation of the synthetic materials as potential cytotoxic agents. This work programme will last 24 months. Training content (objective, benefit and expected impact) The objective of the programme is to acquire experience in multistep natural product synthesis in a stimulating research active environment. In addition to the development of new synthetic methodology and generation of cytotoxic compounds, the experience gained is expected to enable the applicant to continue with an independent academic career. Links with industry / industrial relevance (22) Glaxo-Wellcome and Smithkline Bechham pharmaceuticals have an active interest in the research programme and will evaluate materials.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Measuring the impact of DIgital CulturE' under Horizon 2020.

assistant: **Concept**

The goal of inDICEs is to empower policy-makers and decision-makers in the Cultural and Creative Industries (CCI) to fully understand the social and economic impact of digitisation in their sectors and address the need for innovative (re)use of cultural assets. To this end, inDICEs will (i) Develop a comprehensive methodology to measure and assess the economic and social impact of digitisation of cultural heritage on the access to European cultural goods and services and their modes of production; (ii) Produce in-depth comparative analyses of the impact of digitisation and IPR regulations on the access to European culture and on creative cultural production; (iii) Formulate policy recommendations and develop novel solutions and business models to overcome bottlenecks in the creative (re)use and consumption of cultural assets; (iv) Establish an open observatory to track policies and trends over the long-term; (v) Empower Cultural Heritage Institutions (CHIs) to make strategic self-assessment about their readiness for the Digital Single Market and adaptation to the current legal frameworks in order to foster their digital transformation.As a result, policy-makers will have a solid framework to assess the impact of cultural heritage and a dashboard to keep track of the advancement of the impact of cultural heritage in Europe. For their own part, CHIs will be able to make strategic decisions that will enable them to increase their positive contributions to the Cultural and Creative Industries and society and advance in the Digital Single Market.inDICEs brings together internationally renowned research groups in the domains of Cultural Economics, IP Law and Digital Humanities, representatives from the CCI with deep insights in the sector, Non-governmental organisations with
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Testing, improving, and co-creating Guidance and Tools for Real World Evidence Generation in Europe and use for Decision-Making in Europe: GREG' (GREG), addressing dissemination and exploitation.

assistant: **Impact**

Europe generates real world health data (RWD) that has the potential to inform the development and evaluation of medicines and medical devices. However, multiple barriers remain that limit the access, analysis, interpretation, and use of RWD, hampering its use. Additionally, the limited uptake of existing guidelines for the generation and use of real world evidence (RWE) adds complexity in the use of RWD to inform decision making. The GREG consortium will leverage the learnings of previous and ongoing key RWE initiatives to fill these gaps by generating, pilot-testing, and disseminating evidence-based guidance and tools for the use of RWE to inform the development and evaluation of medicines, medical devices, and combinations. To achieve these goals, we will work with key stakeholders to iteratively test and improve our guidance and tools, backed by case studies from previous successful and unsuccessful examples. We will engage with the most relevant European RWE initiatives and access the largest network of RWD partners in Europe, namely the European Health Data and Evidence Network (EHDEN) through our partner, the EHDEN Foundation. Additionally, we will provide multi-stakeholder gatherings (including patient and public representatives) to promote the dissemination, adoption, and implementation of RWE for decision-making in Europe.Our public and private partners will co-create use cases working closely with key regulatory and health technology experts in bespoke fora. These will be used initially to evaluate existing guidelines, and later to pilot-test the GREG guidance and tools.Our outputs will include training for all involved stakeholders on the use of our guidance and tools, and practical templates to facilitate regulatory and health technology/payer submissions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Convergence of internet-atm-satellite'.

assistant: **Objectives**

Main Objective The objective of COIAS is to demonstrate the feasibility of designing the Global Internet Infrastructure (GII) based on ATM and satellite networks. The implementation will rely on the capabilities and functionality of the new generation of Internet protocol Ipv6. The project will focus mainly on performance, quality of service (QoS), mobility and security features. Several applications; such as Air Traffic Control, Air Navigation and widespread personal applications will be demonstrated on the COIAS platform. Technical Approach Each project partner is already involved in the development of new generation communication products dealing with Internet, ATM or satellite. The COIAS project team intends to participate actively in the standards forming bodies; in particular the IETF (Internet Engineering Task Force) groups. This should lead to the efficient dissemination of the R&D results and provide immediate feedback on the technical choices of COIAS. COIAS intends to address important technical issues such as: Internet and ATM QoS mapping, RSVP signalling over ATM and satellite links, IP flows aggregation, network resource optimisation, load balancing between ATM and satellite networks, security for mobile access and reliable multicast transport protocol. The second stage of the project will be the design phase which will be led by two well known research labs and four industrial partners that are already working in the Internet and ATM domain. The development phase should provide IPv6 protocol stacks with the added functionnalities (mobility, security, QoS management) enabling existing applications to run and benefit from those new communication protocols. The platform integration phase will lead to the availability of a European platform allowing the evalu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Improve and assess repair capability of aircraft structures' (IARCAS), addressing dissemination and exploitation.

assistant: **Impact**

In order to achieve a significant reduction of the maintenance and operating costs of civil transport aircraft - while keeping the standards of safety and taking advantage of new trends in airworthiness regulation - improvements of existing repairs and extension of allowable damage sizes for primary metallic structures are required. These improvements can only be achieved through the development of new calculation methods and the use of improved repair processes. Repair principles involving new technologies and advanced metallic materials, which are likely to be incorporated in new aircraft, will also be investigated and improved. These enhanced repair designs and tools will be compared and validated using realistic tests on fuselage or wing components. The proposed project is clearly aligned with the aims and objectives of the FPV technology platform, which is focussed on the improvement of operational capability and safety of aircraft.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Total costs and benefits of biomass in selected regions of the Eurpean Union'.

assistant: **Innovation**

Objectives The objective of the study is to fill the existing analytical gap on the external costs of the energetic use of biomass. It will thereby supplement the research on external costs of energy under the external cost accounting framework ExternE developed for the European Commission (DG XII). In addition to ExternE's focus on toxic air pollutants, the study will also take into account impacts on soil and ground water as well as the global warming issue. Since possible impacts of biomass are highly dependent on the fuel types and conversion technologies used, the study tries to cover a broad range of possible biomass applications. Thus, six case studies are carried out, each dealing with a different biomass technology using a different biofuel in a different country of the EU. This approach will also allow to study the legal, institutional and social framework for the energetic use of biomass and to identify incentives, as well as obstacles to its dissemination. Technical Approach The research will be based on the impact-pathway approach for the analysis of external costs as developed under the ExternE project. Based on specific, already operating examples of six different technologies for the energetic use of biomass, the impact pathways from the production of the biomass through its processing and energetic use to the final disposal of remaining residues will be analyzed with respect to their internal costs, emissions, impacts, damages, and external costs. Human-health impacts, global warming, land use (including biodiversity, erosion etc.), and rural amenity have been identified as priority impacts so far. In addition, non-monetizable impacts will be discussed on a qualitative basis. The economic impacts will be modeled on the basis of comparative static input-
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Networking for excellence in the development of innovative, consumer-oriented horticultural food products using the Living Lab approach' (HortiFoodTrends) under Horizon Europe.

assistant: **Objectives**

HORTIFOODTRENDS is a project under which Instytut Ogrodnictwa – Państwowy Instytut Badawczy (InHort) will establish and implement into its practice a long-lasting, interdisciplinary collaboration network with high profile European partners: Københavns Universitet (UCPH), Association Groupe ESA (GROUPE ESA) and Centre de recherche de l'Institut Lyfe (LYFE), in the field of novel food product development, considering the needs of the end-user (consumers and food processing sector), with an approach defined as the Living Lab formula. In accordance with the InHort competence, traditionally strongly linked with horticultural producers and the postharvest management of horticultural commodities, the project effort will focus on creating health-promoting novel foods by using emerging processing techniques dedicated to fruit and vegetable preservation. Obtaining appropriate competences to carry out work in the consumer-oriented formula, and in particular using the Living Lab approach, will provide InHort with a unique tool to enhance the knowledge transfer into the agri-food sector. Cooperation of food technologists (technological knowledge aimed at maintaining the health-promoting properties of processed raw materials) with specialists in the field of consumer sciences (knowledge of communicating with consumers) contrasting with consumers’ needs and preferences as well as market and economic conditions articulated by entrepreneurs (work in the Living Lab formula ), is expected to substantially increase the likelihood of delivering innovative nutritionally and sensory valuable products to the HortiFood market. Thus, a conscious consumer, in line with the idea of the EU strategy ""From farm to Fork"", will have better access to high-quality food products produced using current,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Development Of Scintillator-Based Fast-Ion Loss Detectors For Fusion Devices Using Low-Energy Particle Accelerators' (FILDDEV) under Seventh Framework.

assistant: **Objectives**

Magnetohydrodynamic (MHD) instabilities are ubiquitous in laboratory as well as in astrophysical plasmas. Their interplay with energetic (suprathermal) ions is of crucial importance to understand the energy and particle exchange in astrophysical plasmas as well as to obtain a viable energy source in magnetically confined fusion devices such as ITER.  Experimentally, a detailed knowledge of the wave-particle interaction can be gained from direct measurements of MHD induced fast-ion losses in fusion plasmas. The principal diagnostics to obtain this information in a magnetic fusion device are scintillator based fast-ion loss detectors (FILD) that are located at the plasma edge. A scintillator based FILD acts as a magnetic spectrometer, dispersing the measured escaping fast-ions onto a scintillator, with the strike points depending on their gyroradius (energy) and pitch angle (angle between ion velocity and magnetic field line), thus, giving the full information of the velocity space of the escaping ions at the detector position. The research lines proposed here for the next years aim at gaining a better understanding of the energetic particle acceleration / transport mechanisms induced by MHD fluctuations through innovative diagnosis techniques developed at CNA (Centro Nacional de Aceleradores) and employed in large fusion devices. We plan to exploit the CNA low-energy particle accelerators to develop and calibrated fusion-relevant charged particle detectors as well as to explore new techniques. New radiation hardness scintillator materials with high efficiency against fusion-relevant charged particles and short decay time will be developed and characterized. A natural result of this activity will be a flexible Ion Beam Analysis (IBA) chamber for fusion technology installe