RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Biogenic aerosol formation in the boreal forest'.

assistant: **Objectives**

The main objectives in BIOFOR project are: 1. To determine formation mechanisms of aerosol particles in the boreal forestsite 2. To verify emissions of secondary organic aerosols from the boreal forest site, and to quantify the amount of condensable vapours produced in photochemical reactions of 'biogenic volatile organic compounds' (BVOC) leading to aerosol formation. To fulfil the objectives following tasks will be carried out: In task 1 continuous long-term measurements of submicron and ultrafine aerosol particle size distributions, their vertical net flux and relevant background data are performed in the SMEAR II station (southern Finland; Scots pine stand). Size distributions are measured by two differential mobility particle sizers and the flux by eddy covariance technique. Background data consists of meteorological quantities (including radiation) and vertical profiles of several inorcanic gases. In addition, the states of vegetation (level of photosynthesis) and soil (temperature, water content and bacterial and mycorrhizal activity) are determined. In SMEAR II station the formation and growth of natural, biogenic aerosols can be measured and be connected to the function of trees and soil. The local formation rate of particles and the fate of newly formed particles will be identified. Task 1 includes also data evaluation and data delivery. In task 2 three intensive field campaigns will be arranged in order to determine the concentrations and vertical profiles of organic and inorganic gases possibly acting as precursors of aerosol particles. Also the vertical profiles of aerosol size distribution, hygroscopicity of aerosol particles and nucleation potential of aerosol particles will be measured. Radio soundings to evaluate meteorological conditions in the planeta
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'EU enlargement and South Caucasus Security Building. The need for an integrated strategy' (2002-2006).

assistant: **Innovation**

Background and relevance Foreseeable changes in political geography will increase the European Union's exposure to security threats from the South Caucasus. If negotiations due to commence with Turkey in October 2005 reach a successful conclusion, the E U will directly border Armenia, Azerbaijan and Georgia. Already in 2007, after the accession of Bulgaria and Romania, the Union and the South Caucasus will share maritime borders in the Black Sea. EU interests in stabilising the region will grow accordingly. Moreover, the EU has significant economic interests in the region.The EU is already a significant player in the South Caucasus. It has elaborated various policy instruments that are or can be made relevant for regional security engagements. However, most of these instruments have been designed to fulfil specific purposes and not as elements of an integrated South Caucasus strategy.Scientific aim: The project is based on the recognition that policy instruments within the European Neighbourhood Policy as well as EU accession and co-operation partnerships must be co-ordinated in order to influence conflict resolution and security-building in the South Caucasus. So far, little academic research has been carried out on this subject. The project therefore aims at elaborating advice on integrating and co-ordinating these areas of EU policy towards the three South Caucasus countries, Russia and Turkey in line with an overarching conceptual framework. It will make recommendations on specific areas of co-operation that facilitate regional security building. On this basis, the project will develop policy advice for the implementation work of EU on-site operations. Versatile added value As well as developing the aforesaid policy advice, the project will bring first-rate South Ca
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Polarisation of the developing retina' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

Retinotectal topography is ensured early in development when specific areas of the retina project neurons to stereotypedregions in the visual tectum. The nasal to temporal (NT) and dorsal to ventral distribution of Eph/ephryns in the retina will direct the retinal ganglion cells (RGCs) to generate the proper connections in the tectum. An open question is what controls the distribution of Eph/ephryns in the retina NT pattern. Wnt pathway antagonists induce telencephalon whereas diencephalic fate is promoted by Wnt activity. The eye field is situated between these brain territories and thus we speculate that Intermediate, graded levels of Wnt activity, may confer NTpolarity to the prospective RGSc.We plan to address the role of Wnt pathway in the NT polarisation of the 'prospective retinal cells using zebrafish as a model organism. To study the retina NT pattern we will analyse the expression pattern of genes restricted to NT retina. These will be used as readout of NT pattern when we modify Wnt activity in the retina primordia. To study the role of Wnt pathway in the retina patterning we will perform lack and gain activity experiments. To establish the cells in the prospective eye field, which originate the NT region of the retina, we will perform a fate map of the zebrafish eyefield. We will then be able to modify Wnt activity in specific NT regions of the eye field. The local activity modulation will be driven by transplantation of cells expressing positive and negative Wnt modulators.The modification of the NT pattern after cell transplantation will be assessed by:1. Analysing the expression of NT molecular markers.2. Study of the topographic distribution of RGC axonal arborisation in the tectum out of transplanted cells.These two approaches will link the change in t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Zero Emission flexible vehicle platforms with modular powertrains serving the long-haul Freight Eco System' (ZEFES) under Horizon Europe.

assistant: **Objectives**

Long-haul BEVs and FCEVs need to become more affordable and reliable, more energy efficient, with a longer range per single charge, and a reduced charging time to meet the user’s needs. Next to those, there is a real need to take zero-emission long-haul goods transport in Europe to the next level by executing real-world demonstrations of BEVs and FCEVs spread all over Europe; this also requires that technology soon can deliver on promised benefits (easy handling, similar driving hours & charging/fueling, and high speeds, and ability to operate in complex transport supply chains); flexible and abundant charging points for the rising number of vehicles must be implemented fast and to support this, novel charging concepts are needed. In addition, as multiple needs in the logistics chain exist, require novel tools for fleet managers providing them with better information on ZEV in logistic operation, providing a twin of the real use thereby giving valuable information regarding predictive maintenance, eco-driving etc., providing information on better logistics planning, the (available) charging and refuelling along the route, access to roads and traffic information.ZEFES major outcomes: Executing of real-world demonstrations of long-haul BEVs and FCEVs across Europe to take zero-emission long-haul goods transport in Europe to the next level.  Pathway for long-haul BEVs and FCEVs to become more affordable and reliable, more energy efficient, with a longer range per single charge and reduced charging times able to meet the user’s needs. Technologies which can deliver promised benefits (easy handling, similar driving hours & charging/fueling, high speeds and ability to operate in complex transport supply chains). Mapping of flexible and abundant charging/fueling points and nov
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Development and verification of an innovative full life sustainable approach to the valorisation of municipal solid waste into industrial feedstocks'.

assistant: **Innovation**

Management and segregation of municipal solid waste (MSW) has been increasingly imposed on individuals, with highly variable impacts. Waste2Go will valorise this heterogeneous material that has significant socio-economic costs. It will involve the innovative transformation of  over 55% of MSW, the biogenic fraction, into renewable chemicals, advancing beyond current approaches to bio-refining which employ crop derived feedstocks. A cascade approach will be adopted to maximise value. Annually >180 million tonnes of MSW are discarded in the EU27, (in excess of 1kg per citizen every day). Waste2Go will develop technologies to improve waste management and increase value (social, economic & environmental). This will be validated as Best Available Technology (BAT) by recognised LCA experts. It will extend beyond the state-of-the-art in enzyme based technologies for fine-tuned biomass processing and combine them with intelligent techniques for MSW fractionation and downstream processing. It will unlock economic value from MSW and reduce its serious environmental impacts. MSW will become a sustainable source of raw materials for the chemical industry, replacing fossil sources. It will advance leading EU expertise in:1) Enzyme research, on rapid and controlled substrate digestion;2) Bioprocess engineering and;3) Advanced purification techniques, to maximise value.This project will improve the competitiveness of SMEs in the waste management sector; a sector with the highest proportion of SMEs and the lowest proportion of valued added of any EU industrial sector, although worth over €100 billion p.a. and employing over 1.2 million people.The consortium involves five SMEs, two research institutes and one multinational company providing market pull. The EU chemical industry is the w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project '2013 Epilepsy Research Forum' (ERFIP2013).

assistant: **Concept**

Epilepsy is a brain disorder that is characterised by recurrent episodes of cerebral dysfunction, that is, seizures which are caused by excessive electrical discharges of nerve cells. It is one of the most common serious disorders of the brain.Six million people in Europe have Epilepsy and approximately 300,000 new cases are diagnosed each year.The Epilepsy Research Forum 2013 will seek to contribute to the debate on the coordination of research at national and European Union level as well and to focus on research achievements made to date and the opportunities for further advances.By bringing together a wide spectrum of stakeholders it is hoped that national and European epilepsy research networks will be better coordinated and targeted.With an expected attendance of 500 stakeholders, the Conference will stimulate debate on, in the first instance, promoting research into improving the diagnosis and treatment of epilepsy. The Conference programme will also aim at improving awareness and reducing stigma, in what will essentially be a multifaceted conference engaging clinicians and patients alike.The specific objectives are:-to promote and discuss the opportunities for coordinated, targeted and precise innovative research efforts that would build on the significant gains made by basic and clinical research in the past-the 2013 Forum, whilst aimed primarily at facilitating  research opportunities in epilepsy, will also seek to address the optimal standards of care for people with epilepsy which are still unequally distributed in European Union""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Marine Ecosystems, Animal Resources and Human Strategies in Ancient Mediterranean: Integrated Studies on Natural and Societal Resilience' (MERMAID) under Horizon 2020.

assistant: **Objectives**

Facing todays radical deterioration of marine ecosystems, marine historical ecology has a pivotal role in measuring the impacts of past environmental and human pressures on marine biodiversity, with the aim of understanding the resilience of socio-ecosystems and proposing a sustainable management of marine resources. Recent studies confirm that human groups begun fishing down the food web earlier than previously believed. The Mediterranean, this palimpsest landscape, offers a unique archive of undisrupted sea-harvesting activities and a precious palaeoenvironmental indicator, i.e., the remains of marine organisms from archaeological excavations. Although independent studies have increased our knowledge of how Mediterranean resources were exploited, MERMAID proposes an integrated long-term study to understand: a) how marine resources have been influenced by environmental/human pressures, b) when human impact can first be identified, and c) the ways ancient societies depended on these resources and adapted exploitation strategies. MERMAID will first produce an unprecedented archaeofisheries synthesis (M-ARCHIVES Database) of every available dataset, covering several millennia from the Palaeolithic to the Roman era and Mediterranean biogeographical subdivisions. An unconventional combination of approaches (zooarchaeology, marine biology, isotope analysis, fisheries science, ecological modelling, statistics, input of anthropological, geomorphological and palaeoclimatological data) will then be applied on a critical sample from major spatiotemporal contexts (9,000 specimens from 154 sites) at a multi-scale resolution never envisioned before. The results will be key to reconstruct marine ecosystem states (baselines) through time, provide robust evidence of shifting baselines,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Lighthouse coordinating and supporting the innovation ecosystem for a Healthy, Pollution free Mediterranean Sea' under Horizon Europe.

assistant: **Concept**

The Mission Restore our Oceans and Waters by 2030 provides a holistic and coherent framework for developing a systemic approach to the depollution and regeneration of the basin hydrosphere, which is a striking need in the Mediterranean Sea (MED). In the BlueMissionMed proposal, a multi-actor, trans-sectorial and multidisciplinary consortium, consisting of 6 R&I public institutions, 5 NGOs, 3 industrial associations and 2 SMEs from 5 MS and 2 AC of the MED, proposes to set up, structure and empower a MED Lighthouse supporting the development and deployment of transformative innovative technological, social, business and governance solutions for ensuring a 30-50% reduction of pollution of the basin hydrosphere by 2030. It will be an interactive multi-actors digital platform able to offer to all MED Countries/Regions and stakeholders to access the necessary knowledge and tools. It will build on, connect and structure existing initiatives and activities, including the 9 Pilot BLUEMED on plastics free healthy MED and will exploit the R&I and policy knowledge generated by the funded projects/initiatives on the MED decontamination and restoration, ultimately promoting basin-wide cooperation, commitment and deployment of solutions addressing the Mission objectives. The Lighthouse will also ensure i) coherence, alignment and monitoring of EU, national and local policies, initiatives and actions ongoing the MED basin; ii) an effective provision of technical services, governance and business models to support and guarantee a sustainable socio-economic development of the basin; iii) a well-functioning basin scale innovation ecosystem attractive towards investors and businesses, iv) the required engagement of the society at large, thanks to a robust awareness raising and citizen sci
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'European Carbon Dioxide Capture and Storage Laboratory Infrastructure', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The ECCSEL consortium teams up selected Centres of Excellence on CCS across Europe (Norway, Poland, France, Italy, Germany, Spain, Greece, UK, Netherlands and Switzerland). The mission is to develop (i.e. build and operate) a European distributed, goal-oriented, integrated Research Infrastructure, to:•Provide a dynamic scientific foundation to respond systematically to the urgent R&D needs in CCS at a pan-European level in a short and long term perspective;•Maintain Europe at the forefront of the international CCS scientific community;•Increase the attractiveness of the European Research Area, reinforcing the research-based clusters and improving their socio-economic impacts;•Optimise the value of the Community financial supportThe existing and new ECCSEL laboratories will be owned by the involved partner institutions.  They will, however, be developed and made available for the ECCSEL program, governed by an overall agreement. It is foreseen that ECCSEL will gradually become ready and accessible starting from 2015.The main objective of the ECCSEL Preparatory Phase project (PP) is to address the primary tasks necessary to establish a new distributed, goal-oriented, integrated pan-European infrastructure for state-of-the-art research on technologies enabling CO2 capture, transport and storage (CCS). The PP Consortium has 15 participants from 8 member states and 2 associated countries.The PP will be split into two phases, phase I and II, that will build on each other. The first phase will last for two years and focus on legal, financial and strategic work. It will be structured in six Work Packages; WP1 Legal and governance structure, WP2 Financial strategy, WP3 Infrastructure development plan, WP4 Dissemination and outreach measures, WP5 Implementation strategy, and WP6
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Elucidating and targeting the mechanisms encoded in the genome of long-lived individuals to improve healthy ageing' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Advancing age is the major risk factor for many serious illnesses, including cancer, cardiovascular disease, and dementia. The rising number of older individuals is thus causing a major burden of ill health. However, individuals that reach an exceptional old age often seem to escape or delay age-related diseases, and part of this trait seems to be encoded in their genome. Hence, by studying the genome of long-lived individuals, we may be able to identify mechanisms that could be targeted for healthy ageing in the general population. My previous work suggests that large genome-wide association studies (GWAS) of long-lived individuals can be used to identify genetic variants involved in longevity. However, the common genetic variants thus far identified using GWAS only explain a minor part of the genetic component of longevity. This trait, therefore, may well be mainly determined by rare genetic variants, which can be detected using whole-genome or exome sequencing of long-lived families or exceptionally long-lived individuals. The aim of the proposed project is to establish the effect of genetic variants identified in genetic studies of long-lived individuals on general health and lifespan using cellular models and, subsequently, model organisms. To this end, I will use CRISPR/Cas9 gene editing to generate transgenic cell lines and mice that harbour genetic variants in candidate genes and pathways identified through GWAS and sequencing studies of long-lived families and individuals. I will subsequently use this information to create a high-throughput screening assay to identify compounds that can pharmacologically recapitulate the observed in vitro effects. As a proof-of-principle, I will start with functional characterisation of rare variants in genes involved in insuli