RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Switchable rhodOpsins in Life Sciences' (SOL) under Horizon 2020.

assistant: **Objectives**

Bistable rhodopsins are naturally photosensitive G-protein coupled receptors (GPCRs) that can be toggled between stable ON and OFF states using light. They are responsible for photosensitivity and vision across animals (including humans), and a potential source of powerful optogenetic tools enabling bidirectional control of influential intracellular signalling cascades across all body systems using light. Lack of understanding of structure-function relationships for these proteins curtails understanding of their biology and their engineering for optogenetic purposes. PI Kleinlogel first demonstrated that chimeras between bistable rhodopsin and ligand GPRCs can be functionally active and provoke a strong physiological response when expressed in vivo. PI Schertler has extensive experience in the structural analysis of rhodopsins and has successfully solved the first structure of a recombinantly expressed bistable rhodopsin. PI Hegemann has longstanding experience in the spectroscopic characterisation and engineering of photoreceptor proteins and is one of the founding fathers of optogenetics. PI Lucas pioneered cellular systems suitable for analysing spectral properties and G protein selectivity and had a leading role in elucidating the physiological role of the bistable rhodopsin melanopsin.Together, the team aims to understand how structural features of these influential photoreceptors define their bistability, bichromicity, kinetics, and G-protein selectivity (Objective 1). We will exploit this knowledge for rational engineering towards colour tuning and G protein selectivity for optogenetic tools (Objective 2) and to probe physiological functions (Objective 3). The result will be a decisive step towards a general theory of structure-function relationship in photorecep
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Core business reengineering on riche architecture' (COBRA) targeting Fourth Framework.

assistant: **Abstract**

The COBRA project sets out to demonstrate the success of the RICHE architecture and systems in supporting business redevelopment and re-engineered processes. The main objectives are to:- Prove that the application of re-engineered business process with supporting client/server systems delivers business benefits in health care, and that it is applicable to other similar forms of industry to improve business performance.- Demonstrate how the technology is applied to support and enable the re-engineering of core business processes.- Show how the RICHE architecture and technology can be used to deliver improved services and better performance in a hospital multi-disciplinary workgroup environment.Specific objectives for the hospital during this projects are to:- reorganise the way the hospital conducts its business;- treat more patients (60% more) on a day case basis over the next 3 years;- provide a much more efficient and effective service for patients;- better support the operational needs of health care professionals.Approach to the WorkWest Middlesex University Hospital is a major London hospital will provide both project management skills to manage and direct the project as well the commitment of senior hospital management and clinical staff to the success of this project. WMUH will subcontract ATA to provide the necessary BRP skills and resources to guide the re-engineering activities and co-ordinate this activity with the systems development work. Irish Medical Systems has primary responsibility for the development and implementation of the supporting software technologies. The main phases of project activity will be:- BPR analysis and Redesign- Supporting Technology requirements definition and development- Pilot operation- Implementation of new processes and techno
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Thorium nuclear clocks for fundamental tests of physics' (ThoriumNuclearClock) targeting Horizon 2020.

assistant: **Abstract**

Th-229 has an exceptionally low-energy excited nuclear isomer state with an excitation energy of only a few electron volts, making it accessible to laser manipulation. With a predicted relative radiative linewidth of 1e-19, constructing a Thorium nuclear clock becomes possible that could rival todays most advanced optical atomic clocks.The few-eV transition emerges from a fortunate near-degeneracy of the two lowest nuclear energy levels. However, the Coulomb and strong-force contributions to these level energies differ on the MeV level. This makes the Th-229 nuclear level structure uniquely sensitive to variations of fundamental constants and ultralight dark matter.Very recently, the applicants have proven the long-sought existence of the low-energy isomer, determined the lifetime in different electronic environments, quantified the nuclear moments and charge radius based on the hyperfine splitting, and constrained the isomer energy. However, knowledge on the electronic and nuclear properties is still insufficient to exploit the Th-229 system for fundamental tests.This project aims to close this gap and realize three prototype nuclear Thorium clocks using complementary approaches in trapped ions and solids. We will develop customized VUV laser systems and perform precision spectroscopy of the Th-229 nuclear transition. Comparing these clocks among each other and with state-of-the-art optical clocks will allow us to benchmark the new frequency standard before ultimately applying it to test fundamental physics. This project requires a unique combination of experimental and theoretical expertise in atomic and nuclear physics, high precision metrology and fundamental symmetries. Furthermore, special infrastructure is required for (distributed) clock comparison, precision sp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Generation of human experimental models of Bernard-Soulier Syndrome and Glanzmann Disease using cellular reprogramming' (2007-2013).

assistant: **Concept**

Glanzmann's Disease, also known as Glanzmann's thrombasthenia (GT), and Bernard-Soulier syndrome (SBS) are autosomal recessive rare platelet disorders, characterized by severe bleeding because of the absence, reduction or dysfunction of several glycoprotein receptor complexes in platelets. Both normal number and morphology of platelets characterize TG. However, platelet aggregation ability is seriously compromised. Over 100 mutations that alter the expression and/or function of glycoproteins IIb-IIIa (GP IIb-IIIa, or CD41 and CD61) have been described in TG patients. These membrane proteins are members of the integrin superfamily and participate in protein-protein interactions necessary for platelets aggregation and clot formation.Thrombocytopenia, large platelets and frequent bleeding characterize SBS. This disease is caused by mutations in one of the three genes coding for the glycoprotein complex (GP)-IX-V 1b (CD42b-CD42a, CD42d), which function as a receptor for vWF, also affecting platelet adhesion and aggregation. In both cases, current palliative treatment is limited to blood transfusions and DDAVP (desmopressin).We propose the development of human cell models for TG and SBS by reprogramming blood cells from patients with these diseases. Then, we will study if the megakaryocytes and platelets derived from these cells keep the same functional alterations that occur in these patients. Finally, we will introduce a normal copy of the mutated gene in reprogrammed cells and we will analyse if genetic and functional rescues happen.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'From quantum error correcting codes to novel phases of matter in and out of equilibrium' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

In this action, I propose to extend into new directions the already existing deep connections between quantum error correcting codes and exotic phases of quantum materials. Recent developments in analogue and digital quantum devices call for an extension of our understanding of phases of matter to new regimes, and my project will tackle two such directions: non-Euclidean geometries and dissipative open systems. Both of these are also highly relevant to the quest to develop workable quantum error correcting schemes, which will be crucial to scaling up existing quantum computers.Recent years have seen breakthrough theoretical results in the field of quantum error correction, which utilize spatially non-local connections to outperform previous constructions. I will investigate these from a physical perspective, and use them to develop theories of quantum phases in unusual geometries and the novel phenomena that they host. Doing so will both open up new questions in the field of condensed matter physics and also shed new light on properties of such error correcting codes and help design new ones.Error correction arises from a competition of two different dissipative processes: those that cause the errors and those that are engineered to correct them. Designing better error correction schemes therefore requires a deeper understanding of what qualitatively different behaviors can arise in such dissipative systems and to extend the notion of phases of matter to this context. This will lead to ideas that can both help design better error correcting schemes, while also generalizing to other open quantum systems, relevant for various emerging quantum technologies.During the action I plan to work on these problems under the guidance of a supervisor who has an outstanding track rec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Niels Bohr for the 21st Century' (BOHR21), addressing dissemination and exploitation.

assistant: **Impact**

Niels Bohr has been hugely influential both in physics and outside physics, but he is also hugely misunderstood, partly because a few of his writings have been overstudied at the expense of many others. This ERC project is devoted to his philosophical legacy, and will establish an unprejudiced understanding of Bohr, building on a current revival of interest in Bohrs ideas in the philosophy of physics, and extending it among other things to his wider influence in other scientific disciplines, specifically in biology, and on general debates such as on science and objectivity. The project will systematically exploit the resources of the Niels Bohr Archive in Copenhagen, which has only recently started digitising its collections.This ERC project has the ambition to rectify historical misjudgements and to build bridges between physics and philosophy, between different schools in philosophy of physics, between philosophy of physics and philosophy of biology, and even between analytic philosophy and continental philosophy. The relevant resources are only now becoming more widely available. It is a large and methodologically novel project, combining philosophy and history, involving the systematic study of extensive sources, and including applications to philosophy of physics, philosophy of biology and general philosophy of science. Historically informed analysis has long proved to be an important tool in the philosophy of science, and the project will lead the way in applying a historically accurate understanding of Bohrs thought to 21st-century debates.


**Keywords:** Niels Bohr, physics, biology, complementarity, interpretations of quantum mechanics, objectivity, emergence, Kantianism
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Biodiversity Digital Twin for Advanced Modelling, Simulation and Prediction Capabilities' (BioDT).

assistant: **Concept**

With our planet facing an increasing reduction in biodiversity, it is of the utmost importance to understand the way climate, humans, pollution and other factors affect biodiversity. This need is urgent since biodiversity loss directly impacts our ability as humans to live. For example, this loss reduces the efficiency with which ecological communities capture essential resources, produce biomass, decompose organic matter and recycle nutrients. Furthermore, there is increasing evidence that a lack of contact with natural biodiversity impacts human health through negative effects in the microbiome and immune system. microbiome and immune system. Understanding the forces shaping biodiversity is the basis for any rational management of natural resources and will be a key enabler of the EU Biodiversity Strategy 2030 which aims to put biodiversity in Europe on the path to recovery by 2030 for the benefit of people, climate and the planet. In particular, we need to be able to better predict global biodiversity dynamics: how species interact with their environment and with each other. Our goal is to push the current boundaries of predictive understanding of biodiversity dynamics by developing a Digital Twin providing advanced modelling, simulation and prediction capabilities. By exploiting in new ways existing technologies and data available across relevant research infrastructures, the BioDT project will be able to more accurately model interaction between species and their environment. Scientists at Research Infrastructures will be able to use the BioDT to 1) better observe changes in biodiversity, 2) relate these changes to possible causes, and 3) better predict effects of changes based on influences on these causes by either climate or human intervention. Our consortium br
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Business Intelligence Engine for Things in Motion' (NAVALGO), addressing dissemination and exploitation.

assistant: **Impact**

NavAlgo is building a Business Intelligence engine for Things in Motion. Tailored for transport & logistics, it allows users to extract valuable insights from the growing amounts of spatio-temporal data that is being generated (from IoT devices but not only), to improve operations, reduce costs, & meet the challenges of the digital & sustainability transitions.The solution - a horizontal B2B cloud-native application - enables companies to: face the data deluge they experience & to make a strategic use of their data with a very short time-to-market, by turning raw (unqueriable, often inconsistent) data on assets’ movement & transport parameters into a reliable vision of their process;focus their attention on actionable insights related to their supply chain processes, covering anomaly detection, forecasts, and risks of delay or damage. The solution responds to the growing Business Intelligence needs of companies working with sources of Complex Data - with a special focus on data originating from moving assets (including their location). It is a complete technology stack, which - upon deployment - is meant to be accessible to users without technical skills (e.g. sales / business teams). The solution allows clients to retain full control of their data. Its main societal and economic impact lies in helping to achieve more resilient, optimized and environmentally friendly supply chains. NavAlgo is a women-led company (both the CEO and COO identify as women). A deeptech project whose development started in early 2020, this application aims to reinforce aspects of go-to-market, including IP strategy, customer validation for the primary vertical (transport & logistics), market analysis for further verticals, as well as input to the funding strategy.


**Keywords:** Artificial I
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Development of an efficient and robust wireless inductive charging system for material handling electric vehicles' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

In the EU, transportation of goods generates about 28% of total CO2-emissions and consumes 37.5% of total EU energy production. Current intra logistics systems include internal combustion engine (ICE) vehicles, plug-in hybrid electric vehicles and EVs. However, the incorporation of charging infrastructure for EVs in logistics comes with cost and challenges. Within this context, the MagCharge is a unique solution that offers a combination of inductive wireless charging technology with the robustness of concrete, which is vital for industrial applications. The MagCharge core element is the MagPad, a wireless power transmitter pad made using Magment's patented magnetizable concrete material, which consists of a coil for inductive transmission whose efficiency is >95%. It is also perfectly suitable for inductive charging roads as it works with any cover layer (both concrete and asphalt).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Subsea Cooler for Offshore Wind HVDC transformer platforms'.

assistant: **Innovation**

Offshore wind (OW) is a key technology in reaching the EUs and UNs ambitions for sustainable energy production. One of the remaining challenges in making OW financially, technically and environmentally viable is reduction of operational cost. In OW the electrical power is transmitted to shore with high voltage technology. A major challenge is the heat generation in the transformer platform that must be removed. The current State-of-the-art cooling solution is to pump seawater up to the platform using electrical pumps and pass seawater through heat exchangers to chill the cooling loop connected to the rectifiers. This is power consuming, brings in particles from the seawater which is causing frequent clogging of filters and gives high maintenance cost for the operator. Chlorination of the seawater is environmentally challenging.Future Technology(FT), the Norwegian SME company behind the COOLWIND project solves this by introducing the unique patented subsea cooler FSCC® (Future Subsea Controllable Cooler). Instead of pumping cold seawater to the transformer platform, heated water from the converters is circulated and chilled in a subsea mounted cooler. FT proposes by this SME Instruments project to industrialize the prototype FSCC® from current TRL6 to TRL9, to reduce operating cost for the OW platform operators.  Estimates show that up to 3GWh and 1M€/year may be saved.The following benefits are identified compared to conventional systems:No seawater pumps, No filters, No heat exchanger with seawater cooling medium, No expensive salt water piping, No chlorination of seawater/environmental pollution, Less power consumption and Less environmental emission.All international operators show great interest in pursuing this new technology to benefit from the savings and 2 have