RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Fundamentally new strategy for coupling of secondary alkyl boronic esters for the formation of new C-C bonds'.

assistant: **Objectives**

The formation of new carbon-carbon bonds is of central importance in organic chemistry and a prerequisite for all life on earth. In this context, palladium catalysed cross-couplings have emerged as exceptionally powerful and useful methods for C-C bond formation. However, the reaction is largely limited to C(sp2)–C(sp2) bond formation. There are very few examples of cross couplings to form C(sp2)–C(sp3) or C(sp3)–C(sp3) bonds due to inherent problems associated with transition metals. As such a fundamentally new approach is required to solve this problem.We plan to add aryllithium reagents to enantioenriched, secondary boronic esters and form intermediate boron-ate complexes. Subsequent one-electron oxidation of the aromatic ring would result in dearomatization leading to a radical cation which would trigger a 1,2-migration/rearomatization sequence. Exciting preliminary results involving sp2-sp2 bond formation shows that this novel concept is viable (using DDQ as oxidant) and we will study its development and in particular its application in the crucial C(sp2)–C(sp3) bond formation. We will explore organic and inorganic multi-electron oxidants as well as the use of emerging redox photocatalysis. The latter method has the potential to provide an especially green solution to the problem.Even more exciting is the prospect of retaining the boron moiety after oxidation and 1,2-migration as this will allow the rapid construction of highly complex molecules. Once again preliminary results show that the concept is viable and will represent another significant step in organic chemistry. This methodology will be applied to the synthesis of challenging molecules.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Lipoproteins and lipoprotein-tissue interactions in atherosclerosis'.

assistant: **Concept**

One of the major risk factors for atherosclerosis is hypercholesterolemia. The mechanisms linking hypercholesterolemia to atherosclerosis is largely unknown. In the present project we will study:- The formation of atherogenic lipoproteins.- The penetration and deposition of lipoproteins in arterial tissue.- The lipoprotein-cellular interactions in atherosclerosis.LDL is the main atherogenic lipoprotein. This project will further identify and characterize the assembly process of the atherogenic lipoproteins in the liver, and how the formation of these particles are regulated. The assembly process will be studied in cell culture, where the key enzyme diacylglycerol acyl transferase, DGAT, will be characterized and cloned. The importance of the apoB sequence for lipoprotein assembly will be analysed using truncated forms of apoB. In similar systems the requirements for the formation of Lp(a) will be studied. The penetration and deposition of lipoproteins into the arterial tissue will be studied, in vivo in experimental atherosclerosis in rabbits and in vitro in tissue cultures. A focus will be put on the interaction between lipoproteins and the arterial proteoglycans, and the regulation av proteoglycan synthesis in the arterial wall. Proteoglycan synthesis will be studied in cell culture and in arterial tissue. The interaction with proteoglycans will be studied for different subfractions of LDL, as well as for Lp(a) and lipoproteins isolated from subjects with genetic hyperlipidemia. Cell-lipoprotein interactions will be studied in macrophages and smooth muscle cells. Cells will be derived from arterial tissue or from cell lines in culture. In these studies mechanisms for lipoprotein modification will be analysed, especially lipoprotein oxidation and effects of vascular sm
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Europractice IC service: access to cad tools and manufacturing technologies for IC and soc design.'.

assistant: **Concept**

A world renowned service, extended from existing self-funded schemes, will be offered to European universities and research institutes. Through the project, the basic self-funded CAD service will be extended with leading edge CAD tools and design flows for IC, MCM and microsystem design. Through the project, the basic self-funded MPW and small volume service will be extended to easy access for all European universities and research institutes for learning and research including full technical support, distribution of cell libraries and design kits, design consultancy and full checking on submitted designs. The basic self-funded MPW service, covering mature technologies, will be extended with the offer and installation of MPW runs in advanced technologies.DESCRIPTION OF WORKThe whole EUROPRACTICE IC service is run as a broker function whereby EUROPRACTICE acts as the interface between on one side hundreds of customers (academics, research laboratories and companies) and on the other side CAD vendors, foundries, library vendors, assembly and test houses. Concerning the access to CAD tools for learning, EUROPRACTICE negotiates low cost conditions to distribute CAD licenses for IC, subsystem and microsystem design to European universities and research laboratories for educational and non-commercial projects. Concerning access to IC technologies for European companies and academia, EUROPRACTICE negotiates the best conditions with selected foundries to offer low cost prototyping through the organisation of MPW runs. Foundry supplied design kits for the EUROPRACTICE IC technologies will be checked, modified to work with the supported versions of the tools then consolidated onto CD-ROMs for secure low-cost distribution. Whereas the basic MPW service is run on a self-funded basi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Future Feedstock Flexible Carbon Upgrading to Bio Energy Dispatchable carriers' (F-CUBED).

assistant: **Concept**

F-CUBED aims to develop an advanced process concept for the hydrothermal conversion of a broad range of biogenic residues to intermediate bioenergy carriers (IEC) with fuel characteristics suitable for balancing the power grid. The core technology will be scaled up from lab (TRL 3) to pilot scale (TRL 5). F-CUBED will achieve a breakthrough acceleration in the utilisation of unused biogenic residues and wastes by:1) Increasing energy density (at least to 5.5 GJ/m3) and fuel characteristics (complying with ISO/TS 17225‐8:2016-TA3 specifications) of   biogenic residues through hydrothermal processing with an energy yield of 50%.2) Showing at least a 30% improvement on residue processing costs, while obtaining GHG emission savings of at least 60% in using the IEC for heat and power generation.3) Validating experimentally the core process by using continuous hydrothermal reactor (20 kg/hr) and dewatering pilots, in a relevant industrial environment on 3 representative side streams, at Smurfit Kappa Pitea (Sweden, paper sludge), Go Fruselva (Spain, fruit and vegetable wastes) and APPO (Italy, waste olive pomace).4) Making and using a minimum of 100 kg (dry matter) of IEC in a relevant industrial environment.5) Validating the parallel recovery of specific value-added products for each industrial case (nitrogen, phosphorus and potassium, terpenes and olive pomace oil recovery).The F-CUBED approach enables the overall validation of a feedstock flexible process, able to deal with variable feed  characteristics, such as size, composition and pumpability. Advance modelling tools (GIS mapping) will be used to optimize the residue value chains, including logistical impacts. Through its balanced consortium, reflecting the whole value chain with both SME and large companies from diffe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'CYprus Promotes RESearch and Science' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The proposal “CYPRESS”, standing for “CYprus Promotes RESearch and Science”, aims at organising two Researchers’ Night events, one in 2016 in Nicosia, celebrating the 10 years of the events in Cyprus and one in 2017 in Limassol, focusing on Cultural Heritage Research, on the occasion of Pafos being the European Capital of Culture. CYPRESS’ Coordinator, the Research Promotion Foundation (RPF), as the National Agency for supporting Research and Innovation (R&I), has within its remit gained a long experience in organising activities for the promotion of R&I towards the public and especially the younger generation, with the Researchers’ Night events being an integral part of its philosophy since 2006, with or without EC support, but always with vivid support from the National Research System.RPF has secured the collaboration of all Universities in Cyprus, the major Research Institutes and Centres, R&I-intensive Enterprises (mainly SMEs), Public Authorities, End Users and the Civil Society and for the first time Industrialist and Employers’ Associations, covering the Quadruple Helix of Innovation in a complementary way. As a novelty, RPF will also utilise a bottom up approach to attract new partners and will establish links with international partners.Building on past experiences, CYPRESS will bring together researchers from all sectors and disciplines, along with the public, increasing appreciation of the researchers’ work, raising awareness on the importance of R&I for society and the economy and motivating children to take up a career in research. Through a balanced mix of educational and entertaining, interactive activities, aiming at people of all ages, genders and educational backgrounds, and with the contribution of volunteers from the partners and RPF, the events wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Defect identification in metals and semiconductors by experimental and theoretical investigations concerning positron annihilation with core-electrons - application to materials science problems' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Research objectives and content Definite identification of open volume defects becomes more and more important since the investigated systems are becoming more and more complex. This is the case in alloys, compound semiconductors, and fine-grained materials. But a defect identification is possible by correlating theoretical calculations of positron annihilation parameters with experimental data. In these systems we have vacancies on different sublattice eventually decorated with dopant or impurity atoms. Since the positron lifetime gives no direct information about the chemical environment around the annihilation position, Doppler broadening coincidence technique is used for detecting influences from core electrons. The aim of this project is to gain knowledge on the theoretical calculations necessary for the comparison to the experimental data. The routines shall then become modified and applied to materials science problems. Training content (objective, benefit and expected impact) Objective: Widening of theoretical knowledge; becoming acquaintened to the calculation routines developed in Helsinki and becoming able to modify the computing routines; transfer of knowledge to European positron groups for better preparation in global competition. Benefit: Unique possibility to obtain a well founded knowledge on theoretical calculations of positron annihilation parameters. Combination of theoretical calculations and experimental data is a much more powerful tool in defect identification than experiments alone. Expected Impact: Unique defect identification via their chemical environment possible - keeping lead over american and asian research groups. Links with industry / industrial relevance (22) No /Daimler-Benz Aerospace Airbus GmbH (DASA) (precipitation hardened alloys;
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Non-perturbative dynamics of gauge fields, d-branes and topological theories.' (1998-2002).

assistant: **Innovation**

Studies on the non-perturbative properties of (non) Supersymmetric Gauge Theories are proposed. In this context, Topological Theories could provide powerful tools for the analysis of non-renormalization properties, instant on effects and confinement.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Visual object population codes   relating human brains to nonhuman and computational models with representational similarity analysis'.

assistant: **Objectives**

Two major challenges facing systems neuroscience today are (1) to relate computational brain theory with its notions of parallel computation and population-code representation to massively multivariate spatiotemporal brain-activity data as acquired with functional magnetic resonance imaging (fMRI) and cell recording and (2) to relate brain representations in animal models (e.g. nonhuman primates) to human brain representations. This project tackles these challenges with a focus on visual object recognition in human and nonhuman primates. Object recognition is a still poorly understood key problem of computational neuroscience with implications for cortical computation in general. We will test computational models and relate representational content of population codes between human and nonhuman primates by means of a novel multivariate technique called representational similarity analysis (RSA). The core idea of RSA is to characterize a given brain representation by a dissimilarity matrix of stimulus-evoked activity patterns and to visualize and statistically compare such dissimilarity matrices. In contrast to existing approaches, computational models here form an integral component of the analysis of brain-activity data. We will match up representationally homologous regions between human and nonhuman primate and determine which computational models best explain the empirical data (from human and nonhuman primate fMRI) for each brain region. Moreover this project will further develop the technique of RSA and provide an easy-to-use and freely available Matlab toolbox to the community. By richly relating brain theory to data and human to nonhuman primate studies, this project bridges major divides and will contribute to a more integrated systems neuroscience.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Surveillance of cerebral palsy in Europe: prevalence rates in chilhood populations, trends over time and risk factors' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Objectives:* to harmonize data collection on children with cerebral palsy, using a standard definition and an agreed minimum data set including perinatal risk factors for cerebral palsy. * to compare birth cohort prevalence rates for cerebral palsy over time, between populations, and within subgroups (eg. low birthweight) and to examine the extent to which variations can be associated with differences in prevalence of risk factors. * to provide protocols for future collaborative studies using the framework developed.Cerebral palsy (CP) is one of the most commonly occurring disability in young children, making heavy demands on health, educational and social services. It occurs in 1 to 2 per 1000 live births, although in some high risk groups, such as babies born very early or very small, the rate may be as high as 80 per 1000live births. Both children and adults with CP draw on additional services which may range from specialised help at home or at school, to permanent residential care. In order to monitor trends and variations of rates of cerebral palsy, it is necessary for areas in different countries to collaborate. Variations in prevalence rate of cerebral palsy may be due to differences in definition of cerebral palsy, in the completeness of ascertainment and in the survival rate of low birth weight babies. Any remaining difference in prevalence between different populations, after standardising for these factors, may be associated with differences in obstetric and neonatal health care policies. The objective of this proposal is therefore to develop a framework, which will provide reliable estimates on cerebral palsy in children in Europe, on changing prevalence rates, particularly within birth weight groups. This project cannot be achieved at a national level due t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Citizen Led Air pollution Reduction in Cities' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

CLAiR-City will apportion air pollution emissions and concentrations, carbon footprints and health outcomes by city citizens’ behaviour and day-to-day activities in order to make these challenges relevant to how people chose to live, behave and interact within their city environment. Through an innovative engagement and quantification toolkit, we will stimulate the public engagement necessary to allow citizens to define a range of future city scenarios for reducing their emissions to be used for supporting and informing the development of bespoke city policy packages out to 2050.Using six pilot cities/regions (Amsterdam, NL; Bristol, UK; Aveiro, PT; Liguria, IT; Ljubljana, SI; and Sosnowiec, PO), CLAiR-City will source apportion current emissions/concentrations and carbon emissions not only by technology but by citizens’ activities, behavior and practices. CLAiR-City will explore and evaluate current local, national and international policy and governance structures to better understand the immediate policy horizon and how that may impact on citizens and their city’s future. Then, working with the new methods of source apportionment to combine both baseline citizen and policy evidence, CLAiR-City will use innovative engagement methods such as Games, an App and Citizen Days to inform and empower citizens to understand the current challenges and then subsequently define their own visions of their city’s future based on how their want to live out to 2050. The impact of these citizen-led future city scenarios will analysed, to develop city specific policy packages in which the clean-air, low-carbon, healthy future, as democratically defined by the city citizens, is described and quantified. The results of the CLAiR-City process will be evaluated to provide policy lessons at
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Unprecedented spatial control of porosity and functionality in nanoporous membranes through 3D printing and microscopy for polymer writing' (3D-FNPWriting) targeting Horizon 2020.

assistant: **Abstract**

Membranes are key materials in our life. Nature offers high performance membranes relying on a parallel local regulation of nanopore structure, functional placement, membrane composition and architecture. Existing technological membranes are key materials in separation, recycling, sensing, energy conversion, being essential components for a sustainable future. But their performance is far away from their natural counterparts. One reason for this performance gap is the lack of 3D nanolocal control in membrane design. This applies to each individual nanopore but as well to the membrane architecture. This proposal aims to implement 3D printing (additive manufacturing, top down) and complex near-field and total internal reflection (TIR) high resolution microscopy induced polymer writing (bottom up) to nanolocally control in hierarchical nanoporous membranes spatially and independent of each other: porosity, pore functionalization, membrane architecture, composition. This disruptive technology platform will make accessible to date unachieved, highly accurate asymmetric nanopores and multifunctional, hierarchical membrane architecture/ composition and thus highly selective, directed, transport with tuneable rates. 3D-FNPWriting will demonstrate this for the increasing class of metal nanoparticle/ salt pollutants aiming for tuneable, selective, directed transport based monitoring and recycling instead of size-based filtration, accumulation into sewerage and distribution into nature. Specifically, the potential of this disruptive technology with respect to transport design will be demonstrated for a) a 3D-printed in-situ functionalized nanoporous fiber architecture and b) a printed, nanolocally near-field and TIR-microscopy polymer functionalized membrane representing a thin se