RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Rapid Damage Assessment Telematic Tool' (RADATT) under Fourth Framework.

assistant: **Objectives**

The purpose of RADATT is to provide an overall methodology for supporting emergency response management in natural disasters, particularly earthquakes, on the basis of a rapid estimate of the damage done. Integration of existing databases and natural hazard models with satellite-imaging data will provide a fast sound estimate of damage, with results immediately available on the Internet and elsewhere. The emphasis will be on analysing user needs and defining the functional specification for an appropriate software system architecture.An overall methodology for rapid estimation of damage from natural disasters, and support for decisions on response and recovery when they occur, involves integrating several components within a single user interface. They comprise remote sensing and earth-science database information, GIS technology, analytical modelling and image processing techniques.Integration of near real-time satellite imaging data with existing databases and natural hazard models will provide rapid and reliable estimates of damage. The results can be made immediately available via a network such as the Internet.After an earthquake, a great amount of money is always spent for the mitigation-rehabilitation process. Consequently, any improvement to the planning of mitigation-rehabilitation has a direct impact in terms of economic-technical benefits for EU.The proposed effort will concentrate on analysing user requirements and defining the functional specification for a software system architecture to achieve the above goals. Major Validation SitesGNDT, Italian Group of Earthquake Disaster Prevention, Rome, ITMunicipality of Lisbon, PTRegion of Crete, GRUsersThe users are operative units of the Italian Group of Earthquake Disaster Prevention, the Portuguese National Civ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'An experimental and bioinformatic toolbox for functional epigenomics and its application to epigenetically making and breaking a cancer cell' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Epigenetic alterations can be detected in all cancers and in essentially every patient. Despite their prevalence, the concrete functional roles of these alterations are not well understood, for two reasons: First, cancer samples tend to carry many correlated epigenetic alterations, making it difficult to statistically distinguish relevant driver events from those that co-occur for other reasons. Second, we lack tools for targeted epigenome editing that could be used to validate biological function in perturbation and rescue experiments.The proposed project strives to overcome these limitations through experimental and bioinformatic methods development, with the ambition of making and breaking cancer cells in vitro by introducing defined sets of epigenetic alterations. We will focus on leukemia as our “model cancer” (given its low mutation rate, frequent defects in epigenetic regulators, and availability of excellent functional assays), but the concepts and methods are general. In Aim 1, we will generate epigenome profiles for a human knockout cell collection comprising 100 epigenetic regulators and use the data to functionally annotate thousands of epigenetic alterations observed in large cancer datasets. In Aim 2, we will develop an experimental toolbox for epigenome programming using epigenetic drugs, CRISPR-assisted recruitment of epigenetic modifiers for locus-specific editing, and cell-derived guide RNA libraries for epigenome copying. Finally, in Aim 3 we will explore epigenome programming (methods from Aim 2) of candidate driver events (predictions from Aim 1) with the ultimate goal of converting cancer cells into non-cancer cells and vice versa. In summary, this project will establish a broadly applicable methodology and toolbox for dissecting the functional rol
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Automated analysis of opinions in a multilingual context'.

assistant: **Concept**

In the recent years, massive amounts of personal opinions have been posted on the Internet. This allows the companies and institutions to get feedback about their services, provided that they are able to analyse this mass of information.Given that most people prefer to write and read information in their own language, it is clearly relevant to be able to analyse in one language opinions expressed in another language. This is an interdisciplinary topic, called cross-lingual opinion analysis, which involves opinion analysis and machine translation.Although both topics involved have reached a high maturity level, cross-lingual opinion analysis has been little explored. Most of the work done in this field aimed at leveraging resources in English to perform monolingual opinion analysis in another language.The objective of this project is to develop a cross-lingual opinion analysis system. To achieve this goal, the fellow will apply his knowledge in machine translation to adapt the monolingual opinion analysis system existing at the host institution. The fellow will develop a novel approach to map across languages concepts such as the opinion target entity, the corresponding attribute and its polarity. This approach consists of enriching the machine translation system with relevant contextual information.Furthermore several possible architectures of the system will be evaluated and finally a demonstrator will be developed.The underlying technology will eventually be transferred to the industrial sector, since this is one of the missions of the host institution. Thus the fellow will gain interdisciplinary and inter-sectoral competences.In addition, European companies will be able to improve their competitiveness. The citizens will be the final beneficiary since companies and p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Pathogenic Escherichia coli Network'.

assistant: **Objectives**

Escherichia coli form part of the natural gastro-intestinal flora of man and warm-blooded animals. Although most E. coli are harmless commensal organisms, there are many pathogenic strains which can cause a variety of illness in man and animals.There is little doubt that more pathogenic E. coli groups will evolve and be recognised in the future. The research / surveillance community must be proactive in recognising and sharing information on emergent strains so that they can be addressed in a timely manner.Despite considerable research on E. coli O157, there are still areas where a fundamental understanding of these organisms is lacking. Furthermore, technical deficiencies, a lack of harmonisation across disciplines along the food chain and between continents have prevented optimum gain from past and ongoing research.This co-ordination project will form a durable multidisciplinary network of international research groups working on E. coli O157 and other potentially pathogenic strains and serotypes of E. coli with the ultimate aim of reducing the burden of related illness.Key issues to be addressed include:- methods of detection and molecular characterisation of E.coli O157 and other potentially pathogenic strains and serotypes of E. coli;- epidemiology and transmission of E. coli O157 and other potentially pathogenic strains and serotypes of E. coli;- pathogenecity, virulence and emerging pathogenic E. coli;- ecology of E. coli O157 and other potentially pathogenic strains and serotypes of E. coli and- control and management of E. coli O157 and other potentially pathogenic strains and serotypes of E. coli.This network builds on and expands on a previous successful E. coli Concerted Action (CT 98 3935) and will aim to:- improve public health protection;- co-ordinate res
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The Pursuit of Group 13-Group 15 (E13≡E15) Triple Bonds. Their Reactivity and Applications for Materials' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Multiple bonds have an enourmous impact on our lives as they are extremely useful functionalities in important industrial chemical transformations and products. The new millennium has witnessed considerable progress in the chemistry of main group compounds with multiple bonds. In case of elements other than carbon, the utilization of bulky ligands, with the appropriate steric and electronic effects, is a crucial factor in the stabilization of such species. Nevertheless, heteronuclear compounds containing triple bonds between the heavier elements of Group 13 and Group 15 are so far unknown. This proposal will address this knowledge gap by the use of donor-acceptor interactions to stabilize such compounds. The hypothesis rests not only in the stabilization provided by the Lewis base species but also on the electronic features enforced by them. This proposal will utilize the tools of experimental and computational chemistry in tandem, as an efficient and predictive strategy to gain synthetic access to the hitherto unknown triple bonds. These structures will present a multifunctional character, by having two pi-bonds, a lone pair on the Group 15 element, and Lewis base donors. Thus, given the unique bonding situation, they are expected to serve as innovative reagents for the activation of organic small molecules, as well as excellent metal-free catalysts and versatile coordination ligands toward transition metals. Furthermore, the heteroatomic triple bond motif is expected to provide unprecedented precursors for growing high-quality III-V semiconductor films. Therefore, the specific aims of this project are: (i) to comprehensively design the syntheses of these unique compounds; (ii) to develop and exploit their reactivity and; (iii) to harvest their potential in materials s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The development of Personalised Host Response Diagnostic kit' (PHRD).

assistant: **Concept**

Drug resistance is a major reason for failure in cancer chemotherapy and/or modern targeted drugs. While tumours usually initially respond to therapy, resistance occurs within several cycles of treatments, or later on when patients are off therapy. Until recently, acquired and intrinsic resistance mechanisms for therapy were thought to be solely tumour driven. They are usually measured after tumours relapse or after several lines of treatments.  However, in our ERC starting grant (HostResponse No. 260633), we found a novel way to predict resistance to therapy, already after 24 hours after the first drug administration. This discovery resulted in a new stream of research by means of published papers and the formation of special interest groups in cancer research and pharmaceutical disciplines that tackle this paradigm shift in cancer therapy. During our discussions with the cancer community, a clear need has emerged for a Specific Host-Driven Resistant Mechanisms (SHDRM®) diagnostic platform which will serve two (closely connected) markets:(1) the research community – enabling researchers to further examine this new paradigm; and (2) Clinicians- enabling oncologists to identify each patient specific host driven resistance mechanism and repurpose off-the-shelf drugs to counteract the specific factor driving the resistance. PHRD goal is to technically validate and develop a diagnostic platform Prototype for both markets including a clinical study design report which will enable to secure our partners including drug manufacturers, diagnostic providers, and the research community to commit to jointly push the new PHRD standard.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Gene flow from transgenic plants: evaluation and biotechnology' to be submitted under Fifth Framework.

assistant: **Abstract**

This project addresses the likelihood of gene transfer from transgenic (chloroplast) plants to environmental microorganisms. The objectives of this work are to understand and quantify gene transfer under optimum conditions and develop tools for reducing (or augmenting) this gene transfer. Several systems have been developed for this project: microbial (receptor bacteria), plant (chloroplast transgenic plants) and physical environments (lightning induced gene transfer). Gene transfer is expected to a function of the genetic environment of the gene, the number of copies, its persistence in the environment, and physical conditions that increase selective pressure and enhance gene transfer. Other expected results include the establishment of the scientific basis for European policy on transgenic plants and the development of high-level biotechnology companies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'CO2 REduction for long distance transport'.

assistant: **Concept**

The project proposal CORE (CO2 REduction for long distance transport) is a collaborative large-scale integrating project for a call within FP7-SUSTAINABLE SURFACE TRANSPORT (SST)-2011-RTD-1. The project consortium consists of three truck manufactures in Europe, Volvo, Daimler and IVECO, together with 13 other partners in the automotive industry and universities.The objective is to demonstrate a substantial reduction of CO2 emissions, 15% improved fuel efficiency compared to a EURO V engine and at the same time fulfilling EURO VI emission legislation. By using novel technology and combine them in flexible engines with a high level of precise control, performance advantages will be achieved with improvements in emissions and fuel consumption. The research will focus on efficient air management, combustion and control for the diesel engine, together with optimizing the powertrain layout utilizing electric hybridization, downsizing and electrification of auxiliaries and alternative fuels.Research to the aftertreatment system is included to further improve the powertrain efficiency. This will be combined improvements to the base engine friction for developing highly efficient drivelines for long distance transports.CORE is divided into five sub-projects, three that will focus on different engine technologies. These activates are supported by two cross divisional projects where friction reduction and improvements to the NOx aftertreatment technologies are studied. The project results will be assessed by vehicle simulations. Results will be evaluated for legislation test cycles and in real life drive cycles. The project will demonstrate three diesel powertrains and one natural gas truck.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Solidarity, Sovereignty, and Sanctuary on the Seas:  A Global History of Boat Refugees since the 1940s' (SOS).

assistant: **Concept**

In 2015, over one million boat refugees sailed across the Mediterranean. This was not the first time that people took to the seas in search of asylum. During the 1940s, Jewish boat refugees voyaged across the Mediterranean; in the 1970s and 1980s, Vietnamese boat people traversed the South China Sea; in the 198In 2015, over one million boat refugees sailed across the Mediterranean. This was not the first time that people took to the seas in search of asylum. During the 1940s, Jewish boat refugees voyaged across the Mediterranean; in the 1970s and 1980s, Vietnamese boat people traversed the South China Sea; in the 1980s and 1990s, Cubans and Haitians tried to navigate the Caribbean to reach the US; and in the 1990s and 2000s, boat refugees sailed across the Indian Ocean, the Gulf of Aden and the Mediterranean in an attempt to reach Australia, Yemen, and Europe respectively. The central research question framing this project is: how did notions of solidarity, sovereignty and sanctuary influence the experience and reception of boat refugees across time and space? The research team will be guided by the related sub-question: who hindered and who helped boat refugees on their journeys, and why?Each of the sub-projects will examine a) whether there was solidarity onboard between boat refugees, b) whether boat refugees encountered solidarity from non-state actors, such as merchant vessels, fishing boats and NGO search and rescue missions, c) how states responded to boat refugees at sea, and d) whether boat refugees attained sanctuary after their journey.This project’s ground-breaking character lies in three aspects: 1) thinking through seas, 2) going beyond the state, and 3) comparing the experience and reception of boat refugees across time and space. The main sources that th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Photoinduced charge transfer and transport in dye sensitised tio2 films.' to be submitted under Fifth Framework.

assistant: **Abstract**

To design devices to harness light energy and convert it to electrical energy requires a full understanding of photo-induced electron transfer. We propose to investigate electron injection from transition metal complexes and other sensitizers into a nanocrystalline semiconductor film following photo excitation. The charge transfer process can be monitored using femtosecond transient absorption spectroscopy. There are two pathways for electron transfer with very different time constants, involving the singlet and triplet states of the sensitizer, respectively. The pathways will be investigated using two experimental set-ups, with a) 10 fs and b) 100 fs resolution. By examining the ratio of the two pathways under variable experimental conditions we aim to gain information on the transfer mechanism determining factors that will improve the efficiency of light harvesting. Once the electron is transferred to the TiO2 film we aim to examine the time resolved dynamics of the electron transport through the film using a 100 fs pump pulse and a THz (far IR) probe pulse. This will aid in the design of new materials to enhance the efficiency of transport. There are many aspects that are currently unknown about this topic, and we hope to shed some light on them, determining factors such as the mechanism of transport, where the electrons are located in the film, whether the intensity of light and counter ions in the surrounding electrolyte solution effect the mobility of charges. This should give further criteria so as to design far more efficient light harvesting systems. Working with Prof. Sundstrom would present a number of opportunities and benefits for me.(i) working with ultrafast fs lasers,(ii) experience in liquid and solid state dynamics,(iii) exploring the photochemistry of