RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Development of macro and sectoral economic models aiming to evaluate the role of public health externalities on society'.

assistant: **Concept**

The project aims to provide a full-chain analysis related to impact of health protection measures related to priority pollutants as identified by the Environment and Health Action Plan (EHAP), to support the development of cost effective policy measures against pollution related diseases and their wider impacts. The project will achieve this through extending and further developing existing methodologies, models and data to provide an impact-pathway-based model for evaluation of the role of public health externalities on society. The model will be made operational for the selected compounds. Specifically, the objectives are related to the following pollutants: ozone, heavy metals (mercury, cadmium, arsenic, nickel, lead), polychlorinated biphenyls (PCBs), dioxins and indoor air pollution. Since a number of these compounds is carried on particles, PM may be used for some analyses. Main deliverables from the project will include evaluation of a number of emission scenarios using a cost-benefit analysis and incorporating macro-economic modelling. A coherent set of methodologies covering the indicated priority pollutants will be developed and applied in this evolution. The project objectives will be achieved in 7 work packages. WP 1 will extend current policy-relevant emission scenarios to cover all the targeted pollutants or pollution situations, and will provide data on costs of measures. WPs 2 and 3 will review latest research and incorporate information on dose/exposure/concentration - response relationships for health and non-health benefit endpoints of the targeted pollutants. They will also provide monetary valuation data. Based on WPs 1-3 and on macroeconomic analyses done in WP6, WP 4 will develop an integrated tool for the cost benefit assessment, which will be im
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Families of Inequalities- Social and economic consequences of the changing work-family equilibria in European Societies', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

This project investigates social change and its correlates in European societies. In specific, the change in social and economic inequalities associated with new welfare-work-family equilibria. The Project therefore focuses on the changes in women s labour market behaviour, the interlinkage between women s employment and family decisions, families’ capacities to compensate for increasing market risks and the consequences of these developments for social and economic inequalities between families in post industrial societies over recent decades, considering the role of the different welfare and labour market arrangements and the way they evolved. It focuses on the new welfare-work-family equilibria analysing the social and economic consequences of these (dis) equilibria for European societies and their capacity to fully integrate their populations, assuring decent employment conditions, adequate social rights and full social participation.It does so in a strict international comparison, following an interdisciplinary approach between sociology, economics and demography and applying leading edge quantitative methods to adequately treat topics in life cycle perspective.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Environmental signaling and ovarian diseases susceptibility' (ECOSIGNAL).

assistant: **Innovation**

In adult mammals, ovarian function is characterized by regular cyclic changes, which are critical for the egg development, sex steroid hormones production and fertility. These processes depend on the tight regulation of the activity of different ovarian signaling cascades that if altered during critical periods of development can lead to adverse effects on reproductive function. Initial investigations reveal that ovarian development and functions are sensitive to exposure to endocrine disrupting chemicals (EDCs). Endpoints of EDCs action in the ovary have been well investigated; however, insufficient research has been done to identify molecular mechanism(s) by which EDCs perturb ovarian function. Alteration in signaling could provide plausible link between EDCs exposure and pathophysiology of reproductive diseases such as premature ovarian failure, polycystic ovarian syndrome and infertility in women. The aim of the EcoSignal is to investigate if exposure to EDCs affects the function of key ovarian signaling pathways and thus alters ovarian function. To achieve this goal, we will expose ovarian cells to a estrogenic EDCs and the signaling responses and ovarian function will be analyzed using various molecular and cell biology techniques. This includes identification of ERK and AKT signaling as estrogenic EDCs targets and their contribution to the ovarian dysfunctions. Identification of EDC-sensitive signaling in the ovarian cells is an important step in understanding the risk of EDCs on human reproductive diseases. This proposal will allow an experienced US-based postdoctoral fellow to join a research team in Serbia studying EDCs and reproductive biology. The project will provide him not only with an opportunity to identify signaling pathways in the ovary affected by ED
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The work/family issue and the organisation mediation between institutional pressures and practice: companies attitudes with regard to paternity leave' (PATERMEDIAORG), addressing dissemination and exploitation.

assistant: **Impact**

Since the mid-nineties the 'work-family challenge' has become particularly prominent in Europe. This rise of interest is connected to contemporary socio-economic transformations such as the growth of flexible working hours, fonisation of the labour market, intensification of work practices, mobility of the labour force, changing family composition and structure, and the ageing population. The relationship between the worlds of employment and family/private life is becoming a major issue for many people who have to 'juggle' with competing professional, domestic and other needs. This has been reflected in the institutional context in many countries, which is changing in favour of implementation of family-friendly policies and initiatives.However the whole question of the work-family balance is one, which concerns not only the 'individual jugglers' and public policies, but also importantly the world of the enterprise as an organisational mediation between institutional pressures and individual behaviour. Our position is supported by existing literature, which also draws attention to the importance of the organisational context and the relative autonomy of organisations to translate policies into practice.The overall purpose of this two-year project is to examine company attitudes with regard to paternity leave in Belgium. Since July 2002, new fathers have been entitled to two weeks' paid paternity leave. Nevertheless if men want to take paternity leave they can be discouraged through both over and cover questioning of their commitment to work by employers, managers, supervisors and/or colleagues. One significant barrier to men's leave-taking is workplace climates and organisational dynamics. A central objective of this proposal is to improve our knowledge of organisational
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Testing the value of a novel strategic approach and its cost efficacy to improve the poor outcomes in Cardiogenic Shock'.

assistant: **Innovation**

Heart attacks are common and can leave survivors suffering cardiogenic shock (CGS), with its extremely high risk of early death (42% versus 4% for non-CGS) and high incidence of  chronic heart failure, with its associated socio-economic disease burden (ill-health, recurrent heart failure admissions, no return to full time activities, need for expensive therapeutic devices and life-long drugs). Outcomes from CGS are even worse in, females, the elderly (mortality>70%) and high risk sub-groups. The incidence of CGS in Europe alone is >50 000 patients pa. This unacceptably high mortality/morbidity rate represents a true unmet clinical need. No clear strategy exists to improve outcomes, with ad hoc therapies given too late in a spiralling, irrecoverable process.EURO SHOCK aims to improve outcomes for CGS patients. At its core is a robust phase3 randomised trial comparing a novel strategy of very early use of ECMO (Extracorporeal Membrane Oxygenation) to current standard of care. Evidence suggests very early ECMO will halt the spiral of decline and so significantly reduce 12 month death rate and need for heart failure re-admissions. Since both costs of CGS, and ECMO are high a health-economic cost efficacy analysis will be core. A cardiac magnetic resonance imaging sub-study will test novel protocols in sick patients and provide mechanistic data. We will test transfer networks for CGS patients and analyse ECG data to determine which patients benefit most from early transfer.Our multidisciplinary consortium comprises renowned physician-scientists, statisticians, health economists and technology providers, including specialised ECMO SME. EURO SHOCK will impact on heart attack survivors, healthcare providers and Europe`s medical technology sector by 1) reducing healthcare costs
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'COmbining Probable TRAjectories'.

assistant: **Concept**

SESAR implementation will result in an environment using extensive and intensive planning to address complexity imbalances and reduce potential conflicts. Accurate planning requires quantifying forecast accuracy at all planning horizons with the main challenge of combining trajectories with different levels of accuracy.A quality indicator giving the forecast accuracy could enhance the situation: It has to combine uncertainties associated to traffic predictions and to trajectory predictions composing traffic.COPTRA aims to propose, in a TBO, an efficient method to build probabilistic traffic forecasts on the basis of flight trajectory predictions. Its main objective is: Using the improvements brought to Trajectory Prediction by the future TBO environment; bring measurable improvements to Traffic Prediction in ATC Planning, specifically to the prediction of occupancy counts.COPTRA objective is refined in 3 sub-objectives corresponding to its research work packages:1. Define the concept of probabilistic trajectory and its prediction (WP2).2. Using the definition of probabilistic trajectory, define the concept of probabilistic traffic situation and study how probabilistic traffic situations can be built by combining probabilistic trajectories (WP3).3. Apply probabilistic traffic situations to ATC planning (WP4).The management work packages encompass project management (WP1), results dissemination (WP5) and project conclusion (WP6).To achieve its objectives, COPTRA brings together inter-disciplinary competencies where the partners are leading their respective area:• BR&T-E and ITU are experts in trajectory prediction, including the important aspect of prediction uncertainty,• UCLouvain ICTEAM has a proven track in using advanced methods and techniques to address optimal cont
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'EXPLORATHON 2021 - European Researchers' Night in Scotland' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Our proposal builds on the success of EXPLORATHON in Scotland from 2014 to date and will deliver a blockbuster editionof the NIGHT across all of Scotland, utilizing both digital events as well as face-to-face events. Our pan-Scotland partnership learned significant lessons in our online only delivery in 2020 which will allow us to reach more audiences, leave a lasting digital legacy and upskill researchers in how to achieve digital as well as traditional engagement. We will engage with audiences in the main urban centres in Scotland as well as in hard to reach audiences in rural areas and geographically isolated communities in the Highlands and Islands. We will use our full expertise of marketing, social media and styles of engagement to mobilise our researchers and train them to engage with the public. We will use a variety of different styles of engagement from comedy to drama, to online and fun hands-on scienceexperiments to enthuse the public about research and researchers. Working with key partners across Scotland we willshowcase to secondary and upper primary aged school children the array of research careers that are on offer and bustmyths about researchers.


**Keywords:** Public engagement with research,  inspiring young minds,  reaching new audiences,  innovative, engagement,  promoting research careers
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Structural Basis of Protein Synthesis System of Human Cell'.

assistant: **Concept**

This project will elucidate the structure and mechanism of ribosome function through the determination of high resolution crystal structures of human ribosome functional complexes. Currently, the only high resolution crystal structures available for the ribosome functional complexes are bacterial ribosomes containing mRNA, tRNAs in E, P and A sites and several translation factors. Recently, we have determined at medium resolution the first eukaryotic ribosome structure.  Saccharomyces cerevisaiae ribosomes have been chosen for the first step of the study because they have been extensively investigated in our laboratory by biochemical methods and by x-ray analysis.Step One: We will improve the quality of the crystals and determine the ribosome structure of yeast at atomic resolution (about 3Å resolution). These conditions will be used for an investigation of the ribosome functional complexes in order to better understand the detailed mechanism of the translocation of large molecules (tRNA and mRNA) on the ribosome.Step Two: Ribosomes from human HeLa cells will be investigated via crystallization and x-ray structure determination. Ribosome functional complexes developed on yeast systems will be used as models for the creation and structural investigation of human ribosome complexes. Available biochemical data will provide a framework for the interpretation of structural information which will be obtained.The aims:To determine the atomic resolution crystal structure of the yeast ribosome as a model for all eukaryotic ribosome x-ray studies.To obtain crystals and determine the structure of 80S ribosome from HeLa cells.To determine the structure of the ribosome complexes with mRNA and tRNA in ratcheted and non-ratcheted states in order to describe the mechanism of translocat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Nephrops and CEtacean Species Selection Information and Technology'.

assistant: **Objectives**

Twenty-three institutes propose to work together in two Task Groups, i.e. Nehru¿s and cetaceans to develop alternative gear modifications and fishing tactics in collaboration with the fishing industry to reduce by-catches in the relevant Nehru¿s and pelagic fisheries, without reducing the catch of target species significantly.The project consists of ten work packages, as follows:WP1: Management and co-ordination: Statistical planning, modelling and analysis: Species selective Nehru¿s gears: Alternative tactics Nehru¿s fisheries: Biological effects Nehru¿s fisheries: Cetacean by-catch and alternative tactics: Gear modifications Pelagic Trawls - Cetaceans: Impact on Cetacean stocks: Socio-economic repercussionsWP10: Dissemination and implementation The duration of the project is 38 months. Special emphasis will be given to disseminating the results of the worktop the fishing industry and recommending proper implementation of alternative gears and fishing tactics, as wells knowledge transfer between partners from North-West Europe and the Mediterranean. Biological and socio-economic effects will also be evaluated.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Distinguishing infant-directed speech and songs: The distinctive evolution of acoustic features and visual entrainment in infants' in the context of a Horizon Europe call.

assistant: **Objectives**

Given the immature cognitive abilities of infants at birth, caregivers connect with them by producing stereotyped infant-directed (ID) forms of speech and songs in which the acoustic features are modified. Although ID vocalisations are fundamental for establishing social and affective bonds, key aspects of infantcaregiver interactions are still poorly understood. One of the goals of the Musical Speech project is to identify distinctive acoustic adaptations of ID speech and songs by implementing machine learning models to cross-culture recordings from diverse societies, and track the evolution of those acoustic markers over the first year of life. In addition, recent evidence shows that the rhythm of ID singing acts as an effective cue for infants to attend to emotionally and socially-relevant content, such that infants look more to the caregivers eyes during on-beat moments of the songs. This project aims to determine whether rhythm in ID speaking similarly attunes infants attention and whether ID speech elicits distinctive patterns of attention before and after 6 months (as it serves more of a linguistic purpose). Using audiovisual recordings of adults speaking/singing to infants, this project will implement cutting-edge eye-tracking measures to samples of Canadian and Spanish infants. Finally, prematurity and individual differences in neural coding of rhythm, measured with a state-of-the-art EEG paradigm, can affect early interactions. Thus, the eye-tracking outcomes of terms and an additional sample of preterms will be correlated with the EEG signal elicited by rhythmic stimuli. The cross-laboratory studies proposed in this innovative project will comprise training on advanced statistical techniques and leadership, as they rely on the coordination of an international
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Web-portal for Genetic Learning and Training' (1998-2002) under Fifth Framework.

assistant: **Objectives**

Information is less and less accessible because of the high prices of paper editing which is also left behind by the rapidly changing knowledge in science. At present we are on the edge of an important mutation towards e-journalism as a tool for rapid, cheap and interactive access to information; e-journalism has also the advantage of transferring the copyrights from the publishing houses to the author himself. A similar and even more important mutation towards e-learning and e-training is occurring in all fields of science. Genetics has gained in the last 20 years a central role in modern medicine and is affected by these mutations more than other disciplines as documented by the widespread use of the pioneer database in Medical Genetics called OMIM (Online Mendelian Inheritance in Man). Between e-journalism and e-reference books (like OMIM) there is a gap, which could be filled by the existence of e-textbooks, which could combine the advantages of peer reviewing (e- journalism) and that of gathering information in a structured text (reference hypertext).The ultimate goal of the present project will be to provide any user with the possibility to follow a learning path that will suit him/her the best in order to achieve the needed information in the following disciplines: 1. Cancer Genetics; 2.Genetic Counselling. The final form will be a hypertext in the management of which the readers will play an active part.In the venue of the European School of Genetic Medicine (La Nunziata Centre, Sestri Levante) starting in Autumn 2000 the European Genetics Foundation will share space with the main Italian service provider in the field of multimedia design and development, Giunti Interactive Labs (GIUNTI Ilabs, www.giuntilabs.it), a company of the GIUNTI Publishing Group with hea