RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Nutritional zinc, oxidative stress and immunosenescence: biochemical, genetic and lifestyle implications for healthy ageing', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

A hallmark of cellular ageing is the increase in the oxidatively modified proteins. Oxidative damage in lymphocytes is critical given the importance of the immune system for maintaining good health and for successful ageing. Some antioxidant micronutrients in the diet, such as zinc, trol the development and function of the immune cells, the activity of stress-related proteins [metallothioneins, chaperones, ApoJ, PARP-1, NO, MsrA] and antioxidant enzyme (SOD) and help to maintain genomic integrity and stability, thus suggesting diet-gene interactions. During ageing, the intake of zinc decreases due to inadequate diet or/and intestinal malabsorption, thus causing frailty, general disability and increased incidence of age-related degenerative diseases (cancer, infections and atherosclerosis). No focused research has been performed thus far to clarify the intrinsic biochemical mechanisms and the impact of nutrient zinc on the genome during immunosenescence. The applicants will therefore study, the role of zinc in the gene expression and functions of metallothioneins, chaperones, NO, MsrA, ApoJ, telomerase, PARP-1 and DNA-repair as a function of immunosenescence in lymphocytes from old subjects including nonagenarians, as well as in ill old patients affected by age-related diseases and in T-cell clones as in vitro model. Particular attention will be paid to the processing of oxidised proteins by proteasome, which decreases in ageing. The activity of all proteins herein studied is impaired in ageing and this is directly and indirectly trolled by zinc ion bioavailability. The zinc deficiency in the elderly will be evaluated through the screening of polymorphic allele frequency of proteins involved in zinc ion metabolism (such as Hsp70-2 and TNF-alpha) and their relationships t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The role of river margins in moderating the transfer of particulate matter within river systems - implications for catchment and margin management' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Research objectives and content The proposed project focuses on river margins or the riparian zones of the rivers Trent, Severn and Wye in the United Kingdom. Within these major river systems, riparian zones are subject to overbank flooding and, therefore, play an important role in moderating the transfer of particulate matter within the river system. This moderating role of river margins is poorly understood, and yet it has considerable significance for catchment management, since it provides an interface between particulate material supplied to the river system from the catchment, and its delivery to downstream areas as well as providing a resource or pollution source for the local riparian ecosystem. Training content (objective, benefit and expected impact) The aim of the project is to improve the understanding (i) of how the form and structure of the riparian zone influence the nature of local depositional and resuspension processes, and (ii) how human activity such as land management at the catchment scale interacts with the local (reach) scale role of the river margins in influencing the overall sediment budget Thus, the project will contribute to the development of sustainable approaches for integrated land and water management within large catchments and will provide a basis for innovative and sustainable environmental designs for river margin systems. Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'High-Resolution Solar Physics Network' (SOLARNET), addressing dissemination and exploitation.

assistant: **Impact**

This project aims at integrating the major European infrastructures in the field of high-resolution solar physics. The following actions will be taken: (i) realise Trans-national Access to external European users; (ii) enhance and spread data acquisition and processing expertise to the Europe-wide community; (iii) increase the impact of high-resolution data by offering science-ready data and facilitating their retrieval and usage; (iv) encourage combination of space and ground-based data by providing unified access to pertinent data repositories; (v) foster synergies between different research communities by organising meetings where each presents state-of-the-art methodologies; (vi) train a new generation of solar researchers through setting up schools and an ambitious mobility programme; (vii) develop prototypes for new-generation post-focus instruments; (vii) study local and non-local atmospheric turbulence, their impact on image quality, and ways to negate their effects; (viii) improve the performance of existing telescopes; (ix) improve designs of future large European ground-and space-based solar telescopes; (x) lay foundations for combined use of facilities around the world and in space; (xi) reinforce partnership with industry to promote technology transfer through existing networks; and (xii) dissemination activities towards society.The project involves all pertinent European research institutions, infrastructures, and data repositories. Together, these represent first-class facilities. The additional participation by private companies and non-European research institutions maximizes the impact on the world-wide scale.  In particular, the project achievements will be of principal importance in defining the exploitation of the future 4-meter European Solar Teles
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Hamburger synchrotronstrahlungslabor hasylab am deutschen elektronen-synchrotron desy' (1998-2002).

assistant: **Innovation**

Description:The Hamburger Synchrotronstrahlungslabor HASYLAB is located at the 4.5 GeV positron storage ring DORIS at the German Electron Synchrotron DESY in Hamburg. It offers 42 synchrotron radiation beamlines, 13 of them at wigglers and undulators. They are equipped with instrumentation for a wide variety of experimental techniques covering the whole spectral range from visible light to hard X-rays. Typical examples are Photoemission Spectroscopy, X-ray Diffraction, Small AngleX-ray Scattering, Scattering of X-rays under grazing incidence, X-ray Standing Waves, X-ray Absorption Spectroscopy, X-ray Topography, and Inelastic X-ray Scattering. The scientific fields cover physics, chemistry, earth science, crystallography, material science, and biology. The radiation source at HASYLAB offers intensities, which are many orders of magnitudes higher than conventional laboratory sources. Only a few comparable sources are available worldwide.Application:Research work is basically carried out by university groups and groups from other non-profit institutions. The experimental stations are open to all interested groups after their proposal has been approved. It is recommended that potential new users contact the corresponding beamline responsibles before submitting a proposal for a new experiment. If possible new user groups should start working together with experienced groups. Detailed information about beamlines and access can be found on the HASYLAB Web page: http://www-hasylab.desy.de/Project Manager:Prof. Dr. Jochen Schneider, Hamburger Synchrotronstrahlungslabor HASYLAB, Notkestrabe 85, Hamburg 22607, GermanyTel: +49-40-89983815Fax: +49-40-89984475E-Mail: jochen.schneider@desy.de
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Patented modified-immobilized enzymes used in the production of biodiesel at commercial scales using any type of feedstock.' (Usewaste) under Horizon 2020.

assistant: **Objectives**

Biodiesel is an environment-friendly fuel with clear and substantial advantages over conventional diesel, but even at full production it could only ever meet around 8% of the diesel market. Currently, 95% of the world biodiesel is produced from high-grade feedstock such as rapeseed, sunflower oil, and soybean oil (high-grade feedstock). This led to major environmental problems such as serious destruction of vital soil resources, deforestation and large usage of the available arable land. The negative effects of high-grade feedstock use in biodiesel production resulted in their exclusion from REDII - the proposed new EU mandate that caps high-grade feedstock biodiesel blending at 3.8% by 2030. In order to meet REDII’s minimum 6.8% blend from alternative feedstocks, the industry needs to produces biofuel such as biodiesel from secondgrade feedstocks, which has technical issues using current production methods. TransBiodiesel Ltd. has patented TransZyme A, an immobilized enzyme technology for the production of biodiesel using any grade feedstocks (FFAs 0– 100%). Its main features are its tolerance to high concentrations of methanol and water and its long-term operational lifetime, which makes its use economically viable for biodiesel production. This innovative enzyme uses a unique continuous production method, which is more cost effective than current chemical production methods. The Usewaste project aims to leverage this innovation by creating a pre-industrial mobile, continuous enzymatic biodiesel production process on the sites of low-grade feedstock by-product producers. Usewaste mobile lab will be used by the Company to showcase their innovation and eventually foster first commercial partnerships. The company aims to put the biodiesel industry back on track.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Molecular characterisation and developmental expression of anti-Mullerian hormone in the European sea bass (Dicentrarchus labrax)' (MCADE) under Fifth Framework.

assistant: **Objectives**

The overall research objective is to gain more knowledge about the molecular mechanisms involved in sexual differentiation in fish. We propose to isolate and characterise anti-Mullerian hormone AMH1 in the European sea bass (Dicentrarchus labrax ), a species highly used in the marine aquaculture industry , and to analyse its tissue-specific and developmental expression.AMH possesses a key role in mammalian sexual differentiation, causing the regression of the female sexual duct (Mullerian duct) and subsequently inducing male sexual development. Apart from mammals, AMH has also been isolated from lower vertebrates like birds and reptiles. We believe that AMH will also be expressed and possess a key role for sexual differentiation in fish. The sea bass [sb-] AMH gene will be isolated by screening a genomic library. Positive clones will be sequenced and the intron/exon boundaries of the gene will be established.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'kelP side stReam valOrisaTion to dEvelop new biobased valUe chainS' (PROTEUS), addressing dissemination and exploitation.

assistant: **Impact**

Brown algae, particularly L. hyperborea, represent a largely untapped renewable resource in Europe, present in huge volumes along the coastlines of Norway (approximately 60% of global biomass), Sweden, Denmark, Ireland, Iceland, and France. L. hyperborea contains alginate, cellulose, functional polysaccharides like fucoidan and laminarin, phlorotannin’s (polyphenols), as well as protein, vitamins, and minerals, all ingredients in demand in Europe’s biobased value chains. However, current harvesting techniques, particularly widespread use of formaldehyde, is limiting the huge valorisation potential of this promising renewable feedstock.Once brown kelp is exposed to air, chemical and enzymatic reactions quickly begin to rot the harvest. Currently, harvesters mitigate this by treating brown kelp with formaldehyde during and after harvesting. However, formaldehyde causes undesirable browning of some compounds and is toxic, so must be removed through expensive, energy and water intensive washing prior to further processing. This makes valorisation of all but the most valuable alginate fraction (~15% of L. hyperborea biomass) uneconomic; consequently, about 85% of the residual brown kelp biomass is flushed back into the sea unused. PROTEUS addresses the challenge of maximising valorisation of Europe’s L. hyperborea biomass through the optimisation of ALGINOR’s (coordinator) and HYPOMAR’s formaldehyde-free harvesting and extraction technologies and approaches. This will enable large-scale valorisation of Europe’s considerable L. hyperborea resource and conversion of 100% of the biomass into ingredients that will be tested in validated for use by ESSITY (personal-care), OLMIX (feed), VAESS (food), and BORREGAARD (industrial applications) as drop-in replacements for synthetic ma
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Disruptive solution for sexual criminal identification'.

assistant: **Innovation**

More than 5 million rapes are committed globally each year and 1 woman out of 5 will face rape during her lifetime. For 1 000 rapes, only 4.6 rapists will go to jail because rape is highly under-reported but also because police uses tools that can only detect 10% of sperm traces on crime scene.AXO Science is a biotech created in 2010 that develops innovative products for forensic science, police and justice. With this Themis project, the company introduces “STK Spray”, an on-scene sperm-revealing technology that will disrupt the way crime scene investigation is conducted in case of rape. While forensic lamps fail to detect 90% of sperm traces on a scene, resulting in lengthy and often pointless screening of samples sent to labs, STK Spray sharply reveals the presence of sperm on any floor, object, skin, hair, grass… in one single minute. This is a game-changer for Crime Scene Technicians (CST). A major bottleneck for police investigation and sexual offenders DNA identification is unlocked in a few sprays. This performance is backed by a successful proof of concept done during SME Phase 1 project SexAssault-ID.In this Themis project, AXO Science will scale-up this technology and prepare for a massive commercialisation of the product worldwide. STK Spray is a perfect match with AXO Science’s current forensic product portfolio, enabling it to become a one-stop-shop for CST and the first world leader for on-scene sperm trace detection. AXO Science will leverage its existing network of customers and distributors to ease STK Spray market access.This project will trigger durable, hyper growth at AXO Science. The company expects to grab a 17% share of the 134M€ sperm detection market by 2025. It will also achieve a deep organisational transformation with the doubling of headcou
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Including Smallholders in Agricultural Research for Development' (INSARD).

assistant: **Innovation**

Much agricultural research is carried out in isolation from the realities of small-scale farmers in the South and has not recognised their local knowledge and creativity. INSARD partners regard agricultural research and development (ARD) as a process of innovation involving different participants making complementary inputs to produce research results that contribute to development. In this process, farmers do not merely receive new knowledge from research; they are involved in generating it. Smallholders and NGOs are already doing applied and adaptive research to answer questions to which formal research is not giving enough attention, e.g. how to improve local marketing systems. In bridging the gap and bringing smallholders and researchers into joint research on questions central to smallholders’ concerns, civil-society organisations (CSOs) in the South and the North can play a vital role.The main aim of INSARD is to ensure the informed participation of a broad range of European and African CSOs in formulating and implementing ARD. It will do so by:1) Designing a structure for coordination and communication between European and African CSOs involved in ARD and in influencing ARD policy and practice2) Identifying CSOs’ research priorities and a strategy to communicate these to other actors in ARD3) Facilitating joint definition of specific research examples by CSOs and researchers, based on the smallholders’ priorities4) Engaging in policy dialogue with key African and European research organisations and donors.The project will build up a more transparent system for CSOs to provide well-founded inputs and positions in the ARD agenda and its implementation, so that smallholders are central to publicly funded ARD. It will help make research more relevant for small-scale
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Materials for a Magnetic Memory in Three Dimensions' (M3D).

assistant: **Concept**

This project concerns data storage in three dimensions (3D).  Conventional planar (2D) devices are expected to reach the limits of scaling within less than a decade.  We will develop the materials needed for 3D memories based on magnetic shift-register devices, namely dense arrays of vertical magnetic wires in a matrix (race-track memory, IBM patent). In this concept series of bits are shifted along each wire, requiring only one read/write element per wire. Synthesis will rely largely on bottom-up routes (self-organized anodization, atomic-layer deposition, electroplating) to minimize costs. In order to minimize risks, three different strategies will be explored for coding bits: domain walls in continuous wires; solitons with transverse magnetization in a series of magnetic disks; a hybrid route with discontinuous wires with longitudinal magnetization. Two route will be explored for data shifting: magnetic field, or current (spin transfer torque). Addressing each wire will be demonstrated, using writing methods such as thermally-assisted writing, and reading methods such as a TMR junction embedded in the wire.We address call targets density (5-50Tbit/in2), and reasonable cost per Tbit (2-20€), going beyond the scalability of all-planar devices while remaining very competitive in terms of speed and energy consumption (1-10GHz with zero seek time; 10-100 pJ/bit). In all four targets, 3D magnetic memories promise to outperform Hard Disk Drives, providing more storage capacity with less energy consumption.The project brings together the relevant leading academic research groups in Europe. It aims to set Europe ahead of Asia and the USA in 3D storage, a largely unexplored area with a high potential for innovation. Two SMEs are partners, one for material development (SmartMem