RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Neural mechanisms of perceptual Stability in magnitude perception' in the context of a Horizon 2020 call.

assistant: **Objectives**

Magnitude dimensions such as space, time, and numerosity represent fundamental aspects of the external world. A correct perception of these dimensions is needed to understand the spatial properties of the environment and navigate through it, its temporal structure, cause-effect relations, and duration of events, and the number of objects that are present in the visual scene. As magnitude dimensions share similar properties and are often intertwined in the perceptual environment, they are thought to share a similar neural mechanism called the generalized magnitude system. However, while object and events in the space surrounding us usually appear as stable, embedded in a seamless stream of perception, neuronal activity is usually very noisy, and biological sensors like the eye are unstable due to continuous movements. Visual magnitude representation is thus subject to the noisiness of neuronal processing. How does the brain achieve such a remarkable stability despite the noisy nature of its complex machinery? The goal of this proposal is to investigate the brain processes ensuring the stability and continuity of visual magnitude information, using psychophysical, electroencephalography (EEG), and brain stimulation techniques (TMS). Recent studies suggest that to achieve perceptual stability and continuity the brain integrates visual information over time, giving rise to perceptual biases known as serial dependence. While serial dependence has been linked to stability and investigated across several domains, little is known about how magnitude information is stabilized and whether a generalized stability mechanism exists. By taking an interdisciplinary approach, NeSt thus aims to address these issues from a novel perspective and shed new light on the mechanisms ensuring c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Demonstration of a non-thermal process to replace use of sulphites and other chemical preservatives in European wines to meet new European Directive' in the context of a Seventh Framework call.

assistant: **Objectives**

The PreserveWine project (Grant Agreement Number: 262507) funded by the R4SME programme (call identifier: FP7-SME-2010-1) delivered high quality science and technology development. PreserveWine involved the RTD of a novel non-thermal process known as “Pressure Change Technology” (PCT) to extend the shelf life of wine; reducing the need to use chemical preservatives and ensuring high wine quality. This is an attractive alternative in alignment with current EC regulations that are demanding a significant reduction in the use of sulphur dioxide in wines.A novel continuous pressure change technology system to stabilize wine and wine must with high- pressure (500 bar), was successfully developed and validated at a 120L/h scale. This process provides a “cold pasteurization” process, with the advantage that heat-labile components, colour and taste remain unchanged. The novel PreserveWine system significantly reduced the amount of oxygen in wine, thus providing protection against oxidation directly after treatment and during long-term storage in barrels or bottles. Further positive effects including the protection of wine from colour changes and the maintenance of physicochemical and sensory quality of red and white wine and must be more extensively validated. The effects of various parameters such as gas type and retention time have been determined.An industrial scale unit has been designed and specified. Further demonstration at industrial sites to confirm long-term performance, operational costs and economic viability must be undertaken. These include industrialisation of manufacturing processes to enable economies of scale to be achieved. The consortium has identified a number of market opportunities and is keen to bring this development into an industrial stage.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Identification and characterization of targets for the treatment of severe infections caused by Streptococcus pyogenes', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Life-threatening complications from bacterial infections, such as sepsis and septic shock, are the second leading cause of death among patients in non-coronary intensive care units killing up to 146 000 patients each year in Europe. These alarming findings prompted many research groups, to search for novel strategies to treat severe infectious diseases. Many of these approaches are focused on so-called “host effector systems”, since evidence has accumulated that complications from an infection are caused by an over-stimulation of host defense systems that are modulated by bacteria or bacterial products. In severe infections, such as sepsis and septic shock, vascular leakage, increased cytokine levels, and coagulation/fibrinolysis dysfunction are often observed. Thus, the research projects presented in this application focus on the identification and characterization of molecular mechanisms that lead to these complications with a focus on severe infections caused by the human pathogen Streptococcus pyogenes. The results obtained from such investigations could be used for the discovery of novel treatments in infectious diseases.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'From Land to Water: the Role of Development in the Evolution and Diversification of Baleen and Toothed Whales' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Cetaceans (baleen whales and toothed whales) are a distinctive group of mammals that has evolved unique adaptations to live in water. Their impressive fossil record traces their evolution from their terrestrial ancestors (Artiodactyla), to the present aquatic forms. All living cetaceans have flippers instead of limbs, possess a blowhole at the top of the head instead of an anteriorly-positioned nose. They have also developed a characteristic head shape connected to their feeding mode: while baleen whales have lost their teeth and feed using keratinous plates called baleen, toothed whales have evolved the ability to locate their prey using sound waves (echolocation). Changes in prenatal development (ontogeny) played a major role in allowing these animals to evolve the skull adaptions they currently display related to their peculiar traits. Though, little information is available on their development, limiting our understanding of the role of ontogeny in the evolution of modern cetaceans.This project aims to apply 3-dimensional (3D) imaging and cutting-edge geometric morphometric (GM) and phylogenetic methods to quantify the ontogeny of the skull in a diverse sample of cetaceans and terrestrial artiodactyls in order to reconstruct how development has shaped the evolution and diversification of this unique group of mammals. This project will produce high-quality 3D datasets that will be shared in on-line repositories, making rare fetal specimens of toothed and baleen whales accessible for further research and for outreach initiatives. The project will benefit from the expertise in GM methods of a world-renowned researcher and her team, and the vast collection of specimens available at the host institution. Through this fellowship, the researcher will be reintegrated in the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Peer Powered Cities and Regions'.

assistant: **Concept**

The overall aim of PROSPECT is to enable peer to peer learning in regional and local authorities in order to finance and implement sustainable energy plans. The learning will empower them to make use of best practices in developing financing for these plans. PROSPECT will address the needs of regional and local authorities through developing a complete peer to peer learning program addressing them. The learning process will be focused on how different sustainable energy projects and measures have been successfully financed. Peer to peer learning involves sharing information and experience from each other through mentoring activities, work shadowing, and study tours, among others.  Primarily, the networks Eurocities, Energy Cities and FEDARENE will perform “needs assessment and gaps identifications” with public bodies for learning and match these needs with available best practices. Then PROSPECT will select public authorities and agencies and the roles of trainer and trainees will be assigned. The learning program will be divided into five modules that include development of financing for : i) public buildings, ii) private buildings, iii) public lighting, iv) transport (private and public), and v) cross sectional. The overall estimation is for PROSPECT to launch 5 modules per year (fifteen in total) with an average participation of 15 partners per module. This number can differ depending on the demand there is for each module, but as an average value this can be manageable in terms of teaching requirements. The added value of PROSPECT in comparison to other initiatives is that the learning program is not limited to a capacity building process. Instead, the learning curriculum will follow the project steps of energy efficiency finance from the first stages of its develop
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Enabling Crowd-sourcing based privacy protection for smartphone applications, websites and Internet of Things deployments', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Privacy Flag combines crowd sourcing, ICT technology and legal expertise to protect citizen privacy when visiting websites, using smart-phone applications, or living in a smart city. It will enable citizens to monitor and control their privacy with a user friendly solution provided as a smart phone application, a web browser add-on and a public website. It will: 1.Develop a highly scalable privacy monitoring and protection solution with: - Crowd sourcing mechanisms to identify, monitor and assess privacy-related risks;- Privacy monitoring agents to identify suspicious activities and applications;- Universal Privacy Risk Area Assessment Tool and methodology tailored on European norms on personal data protection;- Personal Data Valuation mechanism;- Privacy enablers against traffic monitoring and finger printing;- User friendly interface informing on the privacy risks when using an application or website.2.Develop a global knowledge database of identified privacy risks, together with online services to support companies and other stakeholders in becoming privacy-friendly, including:- In-depth privacy risk analytical tool and services;- Voluntary legally binding mechanism for companies located outside Europe to align with and abide to European standards in terms of personal data protection;- Services for companies interested in being privacy friendly;- Labelling and certification process.3.Collaborate with standardization bodies and actively disseminate towards the public and specialized communities, such as ICT lawyers, policy makers and academics.11 European partners, including SMEs and a large telco operator, bring their complementary technical, legal, societal and business expertise; strong links with standardization bodies and international fora; and outcomes from ove
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'A systems biology approach to tackle PARP-inhibitors resistance and identify novel therapeutic targets to overcome it' (PARPinhibit).

assistant: **Concept**

Inhibition of PARP1 in cancer therapy is a recently adopted strategy to treat cancers where DNA repair is defective, such as breast and ovarian cancer caused by mutations in BRCA1 or BRCA2. In addition, PARP1 inhibitors (PARPi) can be useful even in the absence of BRCA mutations, likely due to pathogenic variants or epigenetic inactivation of other DNA repair related genes. However, development of resistance to PARPi is a significant challenge.To address this challenge, I propose to identify proteins that modulate PARP1 activity that could be used as additional therapeutic targets. The strength of this project is based on a systems biology overall strategy exploiting multiple independent datasets to identify candidates protein interactors, followed by a rigorous biochemical and genetic approach to characterize this interaction. Analysis of identified proteins and their role in PARPi resistance will be achieved at three main levels: a) in-silico and molecular studies of the interaction; b) influence on PARP1 activity and role in PARPi resistance after CRISPR-cas9 editing; c) expression levels in breast and ovarian cancer tissues. Results from this project will illuminate mechanisms of PARPi resistance and generate potential targets for therapy in breast and ovarian cancer. These results will contribute to the reduction in mortality due to breast and ovarian cancer and they will give an answer to this world-wide diffuse challenge.


**Keywords:** Drug response and, or resistance,  breast and ovarian cancer,  PARP1
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Quantum Networks Via Quantum Optical Systems', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

It is widely appreciated that the most advanced future technologies will exploit the laws of quantum physics. The development of such technologies, in particular the controlled generation, manipulation and characterisation of quantum states and entanglement, poses tremendous challenges, which just a few years ago have been considered nearly impossible to meet.The main objective of this project is to initiate state-of-the-art research in Bulgaria on the development of quantum networks, which are an essential part of future quantum technologies. The work will be conducted in close collaboration with several leading research groups from Oxford, Dijon and Turku. The general aim of the research program is the comprehensive understanding of the potentials and limitations of quantum state manipulation of matter using light and quantum light-matter interfaces. The research plan is focused on the following main directions: (1) optimisation of the efficiency of cavity based photon-generation schemes, (2) optimisation of the efficiency of quantum optical information storage, (3) decoherence and dephasing mechanisms in N-state systems, (4) dephasing upon adiabaticity in simple quantum systems, (5) adiabatic and superadiabatic analytic methods and (6) analytic factorisation methods and applications to coherent quantum control.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Regulating nuclear organisation in telomere maintenance and DNA repair: the role of SUMO modification' (2007-2013) under Seventh Framework.

assistant: **Objectives**

The organisation of the genome into separate domains and sub-compartments through higher order chromatin structure is an important means by which eukaryotic cells control nuclear processes such as DNA transcription and repair. Recent evidence has implicated sumoylation as an important regulator of global nuclear architecture as well as allied processes such as telomere maintenance and DNA damage repair. Using the yeast Saccharomyces cerevisiae as a model organism to look at nuclear dynamics in vivo, we aim to elucidate the mechanism by which SUMO modification regulates these processes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Platform for wildlife monitoring integrating Copernicus and ARGOS data'.

assistant: **Concept**

EO4wildlife main objective is to bring large number of multidisciplinary scientists such as biologists, ecologists and ornithologists around the world to collaborate closely together while using European Sentinel Copernicus Earth Observation more heavily and efficiently.In order to reach such important objective, an open service platform and interoperable toolbox will be designed and developed. It will offer high level services that can be accessed by scientists to perform their respective research. The platform front end will be easy-to-use, access and offer dedicated services that will enable them process their geospatial environmental stimulations using Sentinel Earth Observation data that are intelligently combined with other observation sources.Specifically, the EO4wildlife platform will enable the integration of Sentinel data, ARGOS archive databases and real time thematic databank portals, including Wildlifetracking.org, Seabirdtracking.org, and other Earth Observation and MetOcean databases; locally or remotely, and simultaneously.EO4wildlife research specialises in the intelligent management big data, processing, advanced analytics and a Knowledge Base for wildlife migratory behaviour and trends forecast. The research will lead to the development of web-enabled open services using OGC standards for sensor observation and measurements and data processing of heterogeneous geospatial observation data and uncertainties.EO4wildlife will design, implement and validate various scenarios based on real operational use case requirements in the field of wildlife migrations, habitats and behaviour. These include: (1) Management tools for regulatory authorities to achieve real-time advanced decision-making on the protection of protect seabird species; (2) Enhancing scientif
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Dynamic Preservation of Interactive Art: The next frontier of Multimedia Cultural Heritage' (DaphNet).

assistant: **Concept**

This project addresses the theoretical and methodological questions of embodied interaction with multimedia installation artthrough body movement and the use of mediation technology. The ultimate goal is the definition of an effective model for thepreservation of interactive artworks, ensuring future re-use and flexible access. Most interactive artwork produced since the1990s is lost due to the lack of adequate preservation methodologies: as a result the European cultural asset isimpoverished and its potential for economic growth is drastically diminished.The intrinsic interconnection of interactive artworks with computer-based technology requires a multidisciplinary approach topreservation, involving high-profile cultural and scientific competences. With this project I intend to integrate my years ofexperience in the field of audio preservation with strategic competences that come from user-oriented studies in embodiedcognition research, in order to bridge the gap between the world of the arts and the cutting-edge technology for digitalpreservation.This project contributes to the Work Programme H2020 by (1) canalizing advanced competences on the safeguard and thepromotion of European cultural heritage, and by (2) bridging the gap between cutting-edge scientific-technologicalknowledge and the world of the arts, facilitating interdisciplinary innovation and strengthening the competitiveness of theEuropean cultural and creative sectors (Official Journal of the European Union, L 347/225, Artt. 3a and 5.1).


**Keywords:** Interactive Art, Multimodal interaction, Embodiment, Embodied cognition, User-oriented studies,  Multimedia archives, Digital humanities, Digital philology, Gender equality