RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Standard And Modular Microlauncher BAsed services'.

assistant: **Objectives**

The spaceports target to attract to their business case multiple microlaunch concepts available in the market, while microlaunch concepts look forward to launching from multiple spaceports seeking a launch rate at a wider range of azimuths that enable their business plan goals. SAMMBA objective is to develop base services  that provide cost-effective, agile and flexible launch campaigns, empowering spaceports to operate multiple launch concepts while fitting in the cost and the launch rate targeted in the payload market. That goal is tackled through two main axes: the base services design through model engineering systems and the implantation of innovative 4.0 technologies. That approach provides standard and modular base services with the capability of being instantiated at several spaceports, opening launch concepts to a multi-spaceport scenario.SAMMBA main outcome is the deployment of technologies and demonstrators at microlauncher spaceports on the Advisory Board.As a result, SAMMBA contributes to major goal of increasing European competitiveness in access to space, allowing European Spaceports to offer affordable ground services competing technological and economical for the launch services and payload market.


**Keywords:** microlauncher,  modular,  standard,  based services,  cost-effective,  flexibility,  industry 4.0, space port,  launch pad
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Engineering Magneto-ionic Materials for Energy-Efficient  Actuation and Sensing: From Interfaces to Multifunctional Voltage-Tunable Micromagnets' (ACTIONS), addressing dissemination and exploitation.

assistant: **Impact**

ACTIONS proposes a material-based concept to drastically reduce the energy consumption of magnet-based micro- and nanotechnologies. Magnetic systems offer unique advantages for actuation in miniature fluidic and robotic systems, but their integration is hindered because electromagnets are required to create time-varying magnetic fields, causing joule energy loss and heat effects. Alternative control of magnetic materials using an electric field instead of electric current would present an energy-efficient solution. However, established magnetoelectric effects are small and restricted to low temperature or high voltage. Recently, we have demonstrated low-voltage control of magnetic films in liquid electrolytes by exploiting electrochemical reactions and ionic motion. ACTIONS targets the engineering of these emerging magneto-ionic materials to use their immense unexplored potential for low power actuation. The innovative strategy of ACTIONS is to transfer magneto-ionic effects of ferromagnetic metal thin films in liquid electrolytes to 3D nanomagnets and assemblies with defined anisotropy and at critical points. I will use a unique combination of in situ analytical and magnetic techniques to study the magneto-ionic control of magnetization; on this base I plan to attain magneto-ionic micromagnets with voltage-reconfigurable stray fields, which can potentially replace microelectromagnets. Additionally, ACTIONS recognizes the inherent cross-link between electrochemistry and magnetism in magneto-ionic systems as a ground-breaking route to combine actuation and sensing in one material. Interfacial chemistry sensing will be based on the electrical response. The final objective is to identify materials in which actuation and sensing can be programmed on demand by a voltage prot
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Paramagnetism-based methodologies for solution structure determination of biomolecular complexes' under Fourth Framework.

assistant: **Concept**

The goal of the project is to develop an innovative procedure for obtaining high-resolution structures of biomolecular complexes by NMR in solution. The approach is based on exploiting an existing binding site for paramagnetic ions in one of the biomolecules interacting in the complex or creating a suitable binding site by protein engineering. The presence of the paramagnetic metal induces NMR effects that only nowadays can be properly analyzed and provide the long range constraints that are needed to obtain the spatial relationships among the biomolecular components. In diamagnetic complexes the conventional constraints are relatively few and short range. This procedure will constitute a major advance with respect to the current state of the art. In the context of pharmaceutical industries, there is interest in high quality structural information on biomolecular complexes. For instance, structural characterization of protein-DNA complexes is desirable, in view of the need for constructing efficient carriers to take DNA into cells for gene therapy and DNA vaccination.  The procedure will be developed and tested on protein-DNA complexes, and lanthanide ions will be used as metal probes. Two well-characterized DNA binding dornains, representative of two different classes of DNA-binding proteins will be used. The first is a zinc-finger, in which we plan to convert the zinc binding site into a lanthanide binding site. The second is a protein lacking an intrinsic metal binding site, in which we plan to engineer a lanthanide binding site modeled after known calcium binding sites (e.g. EF hand motifs). Rational design strategies will be used. Once the lanthanide binding sites have been created, the proteins will be bound to their target DNA fragments. New NMR methodologies, on
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Prevention of root diseases in closed soilless growing systems by microbial optimization, a replacement for methyl bromide' (MIOPRODIS), addressing dissemination and exploitation.

assistant: **Impact**

The objective of the project is to develop a sustainable system for the prevention of root diseases in closed soilless growing systems in greenhouses by microbial optimisation. The sustainable system may replace the soil grown system, at which the soil fumigant methyl bromide is used in Southern Europe and the run-to-waste soilless system in Northern Europe. Closed soilless growing systems have significant advantages: conservation of scarce water resources, no leaching of nutrients and pesticides and improved quality of products. Disadvantages of the system are rapid dispersal of soil-borne pathogens by the recirculating nutrient solution and accumulation of potential phytotoxic metabolites. Active disinfection with high-tech equipment suppresses or destroys the natural microflora. Recent research has demonstrated a natural suppressiveness by the resident microflora against colonisation by pathogens. Equally passive disinfection with slow (sand) filtration has shown that the resident microflora is not destroyed, while elimination of some of the most harmful pathogens can be achieved. A combination of optimising the natural suppression and passive disinfection will lead to a sustainable technologically simple system, which is also inexpensive and robust. To achieve this sustainable system the following steps have to be taken: diseased conditions and in relation to active and passive disinfection methods; healthy and diseased conditions and, again, in relation to the disinfection met techniques need to be elucidated to improve the efficacy of the method. These three steps provide the basic information towards the sustainable concept of disease suppression in closed systems. The results will be used in the next step: - to enhance the microbial suppression of two root patho
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Advanced Research Infrastructure for Archaeological Data Networking in Europe - plus', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The ARIADNEplus project is the extension of the previous ARIADNE Integrating Activity, which successfully integrated archaeological data infrastructures in Europe, indexing in its registry about 2.000.000 datasets. ARIADNEplus will build on the ARIADNE results, extending and supporting the research community that the previous project created and further developing the relationships with key stakeholders such as the most important European archaeological associations, researchers, heritage professionals, national heritage agencies and so on. The new enlarged partnership of ARIADNEplus covers all of Europe. It now includes leaders in different archaeological domains like palaeoanthropology, bioarchaeology and environmental archaeology as well as other sectors of archaeological sciences, including all periods of human presence from the appearance of hominids to present times. Transnational Activities together with the planned training will further reinforce the presence of ARIADNEplus as a key actor.The technology underlying the project is state-of-art. The ARIADNEplus data infrastructure will be embedded in a cloud that will offer the availability of Virtual Research Environments where data-based archaeological research may be carried out. The project will furthermore develop a Linked Data approach to data discovery. Innovative services will be made available to users, such as visualization, annotation, text mining and geo-temporal data management. Innovative pilots will be developed to test and demonstrate the innovation potential of the ARIADNEplus approach. Fostering innovation will be a key aspect of the project, with dedicated activities led by the project Innovation Manager.


**Keywords:** archaeological datasets
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Center for Glacial Biome Doctoral Network' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Glaciers and ice sheets were long believed to be sterile environments, but just like other large ecosystems (e.g., tropical forests, tundra), they are now widely recognized as one of the Earth’s biomes, teeming with life. Active algae, fungi, bacteria and viruses dominate the glacial environment and they have the ability to change the physical and chemical characteristics of the ice and snow, with global effects. For instance, increasing ice melt rates are observed due to growth of pigmented algae on glacier surfaces and substantial amounts of methane from subglacial habitats are added to the global greenhouse gas budget. Despite their global influence, many of the microbiological processes within the cryosphere remain poorly quantified. A deeper understanding of such processes are relevant to researchers interested in the possibility of life on icy extraterrestrial bodies, the survival and proliferation of life forms on our early Earth (e.g. during the part of the Proterozoic era known as Snowball Earth), and the positive and negative feedbacks that the cryosphere may have on global warming. The microbial communities living in association with icy environments may also harbor unique metabolic pathways, providing novel opportunities in biotechnology. ICEBIO is a Doctoral Network that will train the next generation of glacier microbiology and biogeochemistry experts. The training and research programme is made up of seven interlinked Work Packages (WP). WP1 to WP4 are research work packages at the cutting edge of glacial microbiology and biogeochemistry and these will be supported by three overarching WPs (WP5-7) associated with the management, training, and dissemination of results. ICEBIO will deliver a detailed framework and database of the functional diversity and po
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Food storage in the late fifth, fourth and third millennia BC in the Northern Fertile Crescent' under Horizon Europe.

assistant: **Concept**

FoodStore investigates food storage systems in the Northern Fertile Crescent (western inner Syria, south eastern Turkey, northern Iraq) during the late fifth, fourth and third millennia BC, in order to define the relationship between storage practices, socio-economic complexity and ecological conditions. During these millennia, the area experienced different trajectories leading to the emergence of complex societies, and the storage of food staples was central to these developments. The project has a multi-level design that combines the collection of published data, with the direct study of storage facilities from key archaeological sites. These features will be investigated through a combination of traditional macro-archaeological methods with micro-archaeological techniques from applied geological, chemical, and biological disciplines: microstratigraphy, Fourier Transform Infra-Red Spectroscopy, and phytolith analysis. Key objectives for FoodStore are the establishment of a robust analytical protocol to investigate food storage practices in archaeological contexts; to develop an interdisciplinary framework to tackle issues connected to food preservation; to contribute to the collaboration between archaeology, anthropology and natural sciences; and to enhance the relevance of archaeology to support traditional rural heritage and food management practices.


**Keywords:** Fertile Crescent,  food storage,  social complexity,  social inequality,  food security
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Post-transcriptional and post-translational mechanisms underlying B cell selection by T cells in germinal centers' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Enduring protection from pathogens and robust responses to vaccination depend on the generation of high-affinity antibodies through the germinal center (GC) reaction. In GCs, T helper cells promote the extensive proliferation of high-affinity B cell clones and their differentiation into plasma cells through cellular interactions that modulate gene expression.  Here, we aim to unravel multiple post-gene expression mechanisms, including mRNA and protein stability regulation, that jointly control the outcome of T-B interactions in GCs. Since it is technically challenging to examine gene transcription and cellular contacts simultaneously, a method that links these two processes and measures transcription in-situ is required. To understand how T cell help controls gene expression dynamics and persistence of mRNA transcripts in GC B cells, we will use LN-smFISH, a new method we recently developed that combines imaging of individual cells and single mRNA transcripts within lymph nodes. Through in-vivo manipulation of B cells and co-visualization of single cells and mRNAs, we will define the dynamics of gene expression during T-B contacts and plasma cell generation in GCs (Aim1). Using our specialized in-vivo models, we will examine how modulation of mRNA stability and translation by transcript methylation controls B cell clonal expansion and define which genes are regulated by this machinery (Aim2). Finally, we will examine how the degradation of known and novel key proteins control gene networks and B cell fate in GCs (Aim3). Together, we envision the establishment of a unifying model for how sequential layers of regulation orchestrate the translation of T-B interactions to fate decisions. The findings may lead to improved vaccine strategies and expose new checkpoints for man
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'INNOWAY Key Account Manager and Innovation Specialists Services - NORIMS' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The NORIMS project shall strive to enhance the innovation management capacity of Norwegian SMEs in 2019 by reducing barriers to innovation and to ensure that more great ideas will reach the market. The two distinct types of services under this consultation, a) Key Account Management under the SME beneficiaries of the SME Instrument and FTI and FET-Open under H2020 and b) Services to enhance the innovation management capacity of SMEs will be offered as an integrated part of the general support services of the Enterprise Europe Network Business Cooperation Centre (BCC) in Norway in 2019.


**Keywords:** Innovation management Capacity, Key Account Manager, Innovation Specialist, Enterprise Europe Network, Business Cooperation Centre, KAM, FTI, FET-Open, SMBI
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Are saliva proteins key determinants of host plant specificity in the pea aphid complex?' (APHISPIT) under Seventh Framework.

assistant: **Objectives**

Aphids are insect pests that feed on plant phloem sap and cause feeding damages and transmission of plant pathogens. The pea aphid (Acyrthosiphon pisum) complex is consisted of multiple biotypes each of which specialized to specific legume plants. Aphids use a specialized mouth part to puncture plant phloem sieve cells and suck plant nutrients. During the feeding process, aphids secrete saliva which contains various proteins that might interact with plant proteins. Interestingly, the pea aphids carries various facultative symbionts and one of which, Regiella, is known to increase aphid adaptation to clover plants. This project aims to examine the role of aphid saliva proteins and aphid symbionts in host plant adaptation. Based on previous works in plant microbe interactions, I hypothesize that aphid saliva proteins function like microbial pathogen effectors. Thus, I anticipate that the saliva proteins that are involved in host adaptation process are under high evolutionary pressure and show differential expressions or polymorphisms between biotypes. I will examine transcription profiles and sequences of salivary gland genes of the aphids that belong to different biotypes. Aphid gene silencing and in planta transient protein expression will be employed to examine the roles of the saliva genes in plant-aphid interactions. I will also examine the Regiella strains that does/does not increase aphid adaptation to clover plant to understand the host adaptation mechanisms of the aphids. I will conduct transcription analysis and saliva proteomics of the pea aphids with and without the Regiella strains. The project will improve our knowledge on the roles of aphid saliva proteins and symbionts in plant-aphid specialization process and will be the first step to contribute to develo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The role of ice proteases in myc-induced apoptosis' (1994-1998) under Fourth Framework.

assistant: **Objectives**

C-myc is a protooncogene, whose deregulated expression leads to inducti of proliferation and apoptosis. Myc-induced apoptosis is mediated by Myc/Max heterodimers and clearly depends on it ability to activate transcription. However, the underlying molecular and biochemical mechanisms are so far poorly understood. In C. elegans genetic studies have identified a genetic pathway for apoptosis. For this pathway the genes ced-3, ced-4 and ced-9 are important. Various data support the idea that the pathways regulating apoptosis in C. elegans and mammals are highly conserved. therefore it is likely that apoptosis will be controlled in cell type-specific fashion, but that the basic elements of the death machinery might be universal. Ced-3 is homolog to the ICE protease whereas ced-9 shows homolgy to the human bc1-2 gene. Both genes seem to be involved in different forms of mammalian cell death. For Bc1-2 it has been demonstrated that it blocks Myc-induced apoptosis. In contrast l to this the role of ICE proteases in Myc-induced apoptosis is not clear. The aim of the proposed experiments is therefore to gain g sights into the role of ICE and ICE-like protease in the process of Myc-induced apoptosis. Training content (objective, benefit and expected impact) With th post-doctorial training I would like to become more qualified for a scientific career. I am expecting to work independently on my own project but in close contact with other scientists. The lab of Dr. Gerad Evan is well-known for their work in the field of apoptosis. During my Ph.D. I became familiar with certain aspects of the Myc oncogene and with this post doc I would like to investigate other aspects of this oncogene namely i role in apoptosis. The ICRF, London is a very famous and well established institute. The fa