RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Deficit irrigation for Mediterranean agricultural systems' (DIMAS).

assistant: **Innovation**

Irrigation uses about 80% of all water diverted for various uses in the Mediterranean. Nevertheless, increased demand for other uses coupled with water scarcity is putting unprecedented pressures on reducing the share of freshwater used in irrigation. Give n the degree of scarcity in many areas of the Basin, if irrigation water use could be reduced, it could become a major water source, thus releasing resources for alternative use. The objective of this project is to evaluate the concept of deficit irrigatio n (DI) as a means of reducing irrigation water use while maintaining or increasing farmers profits. The DI concept will be the subject of multidisciplinary research at different scales, geographic locations, and with different perennial and annual crops. T he objective will be to develop a workable, comprehensive set of irrigation (DI) strategies that can be disseminated quickly among the various agricultural systems of the Mediterranean Region. The project addresses directly the first topic of the INCO-2002 -B1.2 specific measure, 'research on sustainable irrigation, including deficit irrigation'. Eleven partners from seven different countries (Greece, Italy, Jordan, Morocco, Spain, Tunisia and Turkey), including research and water association institutions wi ll work for three years on the project. Their main activities will be: a) the development of a general summary model of crop yield as a function of water supply, b) the validation of the model for the main irrigated annual (wheat, sunflower, cotton,) and p erennial crops (olive, pistachio, citrus), using common research protocols, c) a survey on physical, socio-economic and cultural conditions for each crop and irrigated area, and d) scaling up by combining the yield model with economic optimization modules th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Large-scale analysis of neuronal population activity' (NEUROPOP) under Horizon 2020.

assistant: **Objectives**

The brain works through the activity of large, spatially distributed neuronal populations. Recent technological advances enable recordings of thousands of neurons from multiple brain structures, offering an unprecedented opportunity to understand neuronal population activity. However, mathematical and computational advances are also required to turn the resulting flood of data into concise principles summarizing brain function. Ideally, these principles would be not just be qualitative, but quantitative: simple formulae that capture the dynamics of neuronal populations, the underlying circuit mechanisms, and their behavioral impact.We will combine large-scale neuronal recording with novel data analysis techniques to study the structure of population activity within and between areas. We will use twelve 960-site probes simultaneously to record from several regions of cortex, hippocampus, thalamus and other structures in awake mice, complemented by recordings combining single high-count probes with wide-field calcium imaging. Optogenetic stimulation of excitatory and inhibitory populations will probe the mechanistic basis of population activity, and experiments in mice performing a discrimination task will probe its effect on behavioral output. We hypothesize that population activity can be quantitatively summarized by a two-level model: first, a low-dimensional dynamical system that captures the macroscopic activity of excitatory and inhibitory populations in each area as a function of brain state; and second, models predicting each neuron’s activity from the interaction of macroscopic variables with specific signals such as sensory inputs. We will validate our models mechanistically by their ability to predict of the effect of optogenetic perturbations on neural firing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Rural transformation and structural change – A new spatial perspective on trade-offs in household decision-making in low-income countries' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Understanding the decision-making of smallholder households in low-income countries is a crucial step in the design of effective policy measures for development. This task is becoming increasingly complicated as more and more factors (e.g. urbanization, climate change) influence rural transformation processes. Economic research normally singles out individual mechanisms (e.g. income composition) and spatial variability thereof is represented by access to the most important economic center in a region. However, trade-offs between multiple decision factors can lead to complex spatial patterns in livelihoods, often further complicated by multiple accessible economic centers. RTSC proposes an innovative and interdisciplinary framework to capture such complex patterns by modeling decision-making based on the location of a household in two-dimensional space. This framework includes key features such as the development of a microeconomic model of location-dependent trade-offs in household decision-making, the application of advanced statistical techniques to capture them in an empirical analysis based on primary data from Myanmar, and the vision to use RTSC results for evidence-based policy design. Planned as a Global Fellowship, RTSC brings together UGOE, a leading European university in agricultural development economics, and IFPRI, an international key player in providing research-based policy support on matters such as poverty reduction and food security. These host institutions complement each other perfectly providing state-of-the-art expertise in applied economic research and policy support. These conditions can be used effectively by the experienced researcher (ER), as she brings skills in household modeling, fieldwork, and advanced statistical methods. RTSC will, thus
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Social evolution: novel insights from the neglected sphecid wasps' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Social evolution is at the core of evolutionary biology, largely through the seminal work of WD Hamilton on inclusive fitness and the role of genetic relatedness in shaping social interactions and the social organisation of insect societies. Extensions to Hamilton’s original ideas have given a profound insight into the balance that exists between selfless cooperation and egoism within eusocial insect societies, spawning such concepts as worker policing and conflict resolution. These form one element of social evolution. The other element concerns the major evolutionary transition from solitary to truly social (eusocial), yet it has remained largely ignored. This is because the most widely studied social insects (ants, some bees, some vespid wasps) are obligately eusocial, unsuitable models to investigate the evolution of sociality. The sphecid or sand wasps provide an ideal group, although they have been largely neglected. Though most are solitary, a few are facultatively social and exhibit reproductive division of labour. Here I propose to investigate a facultatively social species which exhibits a division of labour in large (10-30 nestmates) groups. The study will integrate behavioural observations in the field to document patterns of nestmate activities with microsatellite genetic analysis of individuals to determine reproductive success. These analyses will tease apart the relative importance of relatedness versus ecological factors, size and age in determining the extent to which an individual cooperates for the good of the society and foregoes reproduction. Experimental manipulations in the field will be used to test explicit hypotheses over the role of relatedness in modulating cooperation. The neglected sphecid wasps offer novel insights into the role of relate
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Advancing HeRitage science procedures for Depth-resolved condition risk assessment of wall paintings'.

assistant: **Objectives**

Although heritage science field already offers a wide range of tools for condition assessment of wall paintings, an efficient on-site full-field depth-resolved inspection is not achieved yet. In practice, heritage professionals often struggle to interpret complex and fragmentary scientific data. Conservators often face challenges in assessing hidden risks and localizing the depth of detected detachments, covered fresco layers, refills, and cracks.The main challenge in wall painting’s condition assessment is that it is inextricably linked to the architectural/archaeological support. The preservation of the pictorial layer, often unique and irreplaceable as in ancient frescoes, depends on the integrity not only of the surface but of the bonding substrate and the structure behind it. Informed and timely interventions by conservators are important to mitigate natural aging processes, and become crucial in case of extreme events (e.g. seismic activities, climate disasters etc.) or anthropogenic damage (both intentional and unintentional, including past restorations etc.). The HeRiDe methodology will be grounded in a scientific protocol that employs cross-correlation formulas to analyze full-field interferometric and thermographic datasets. This approach will differentiate hidden risks according to their characteristics and depth in the stratigraphy of wall paintings. The HeRiDe project seeks to exploit the maximum  yet to be explored potential of the complementary full-field heritage science approach, testing and validating the results on wall painting mock-ups, and transposing the methodology to real case studies. To facilitate its real implementation, a dedicated open source software tool will be proposed to ensure broad access for all international heritage professionals.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Water on TiO2', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Hydrogen produced by sunlight is a very promising, environmentally-friendly energy source as an alternative for fossil fuels, which are limited present on earth and produce green house gases by their combustion. Since the discovery of hydrogen production by photocatalytic water dissociation on a titanium dioxide (TiO2) electrode 40 years ago, much research has been performed to make the process more efficient mostly through a trial-and-error approach. However, fundamental knowledge of how water is bound to the catalyst, what the relation between structure and reactivity is, and what the dynamics of the photodissociation reaction are, is lacking up to now, because no suitable techniques were available. The aim of this proposal is to answer these fundamental questions by looking at specifically the molecules at the interface, before and during their dissociation. With the surface sensitive spectroscopic technique sum-frequency generation (SFG) we can look explicitly at the monolayer of water molecules at the interface. A recent expansion of this technique into two-dimensional SFG will allow us to determine the heterogeneity of the water molecules at the interface. Moreover, the dynamics of the photodissociation of water on TiO2 will be investigated by applying pump-probe sum-frequency generation spectroscopy. At variable delay times after the pump pulse the probe pulses will interrogate the interface and detect the reaction intermediates and products. Due to recent developments of this SFG technique it should now be possible to determine the structure of water at the TiO2 interface and to unravel the dynamics of the photodissocation process. The results will be essential for understanding the fundamentals of the water dissociation process at oxide surfaces and thus for de
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Interferon-focused Innate Immunity Interactome and Inhibitome' in the context of a Seventh Framework call.

assistant: **Objectives**

After a decade of development in model organisms and later in mammalian cells, mass spectrometry-based functional proteomics approaches have come of age and are ready to enable a systematic study of the innate immune system. We propose to cross the large-scale proteomics and innate immunity disciplines to obtain a functionally annotated map of the molecular machinery involved in viral recognition and leading to the hallmark interferon response, through a three-pronged approach: 1. Map the interactome of innate immunity proteins in macrophages to establish the network of components leading to interferon production; 2. Chart the interactions of molecular patterns, mostly nucleic acids, to identify the receptors and sensors at the non-self/self interface; 3. Study viral pathogenicity factors as molecular jammers of the anti-viral response and elucidate their mode of action to uncover critical nodes (inhibitome). Datasets are integrated and released at regular intervals with embargoed windows allowing a network of collaborators/own laboratory to do in-depth validation. New components at data intersections will be tested through loss-of-function experiments and standardized read-outs for the interferon pathway as well as genetic association with autoimmune diseases. Because of its unbiased/large scope and its cross-validating approaches, wherein the newly mapped circuitry is modeled, challenged by inducers and perturbed by viral agents, i-FIVE has the potential to promote a systems-level understanding of the interferon branch of molecular innate immunity. This insight may in turn create medical opportunities for the treatment of autoimmune disorders, septic shoc, arthritis as well as in boosting anti-viral responses.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Photo-switching of smart surfaces for integrated biosensors'.

assistant: **Objectives**

Smart surfaces with switchable properties hold great promise for future integrated sensors. Azobenzene molecules have been demonstrated to switch reversibly between the trans and cis isomer with picosecond time constants, when triggered with an external light source. Due to the different molecular geometries and electronic properties of the isomers, these may be used as molecular switches for realizing smart surfaces. The objective of this research proposal is to establish methods for integrating photo-switchable smart surfaces into miniaturized sensors. For efficient switching this requires on-chip light sources providing sufficient intensity at the location of the molecular switch. Ultraviolet and blue organic light emitting diodes will be integrated monolithically onto dielectric substrates with a periodically nanostructured high refractive index layer. This slab photonic crystal allows for resonant excitation of the molecular switches. Two types of smart surfaces will be studied. First, the reversible switching of wettability between hydrophilic and hydrophobic will be investigated, which is of particular importance for reconfigurable microfluidic chips. Second, the switchable surface adsorption of biomaterials is targeted. The periodic switching of the binding sites between an active and an inactive state will cause a periodic measurement signal. This allows for the use of lock-in techniques with superior signal-to-noise ratio and for subtraction of the background at same position. Combining both types of smart surfaces promises reconfigurable, multifunctional, highly-selective future integrated biosensors. The final goal of the proposed project is to demonstrate for the first time an integrated microsystem with smart surfaces switched by on-chip light sources for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Natural whey-based disinfection formula: a solution for the sanitizing of whole and fresh-cut fruits and vegetables' (WHEYSAN) under Seventh Framework.

assistant: **Objectives**

The purpose of the project WHEYSAN is to provide a solution for two major issues that currently affect to the competitiveness of the participant SMEs: the management of whey and postharvest disinfection of fruits and vegetables (F&V). The whey is the residual liquid fraction that is obtained during the production of cheese. Its raised content of lactose makes it a high contaminant waste which needs to be processed before disposal. Postharvest disinfection of F&V is crucial for extending the market time of the produce, and chlorine is the sanitizer most widely used. However, the likely formation of carcinogenic chlorinated compounds in water has called into question chlorine application, which is already banned in several EU countries.Whey and its derivatives have shown promising perspectives as natural preservatives for disinfection of F&V. The project WHEYSAN aims to develop new technologies for the decontamination of whole and fresh-cut F&V and for the processing of whey to achieve a profitable byproduct with sanitizing properties. For this purpose, the whey produced by the dairy SME will be treated under different processing conditions and the efficacy of the whey derivatives as sanitizing agents for F&V will be assessed. The most successful whey derivatives will be fully characterized. Also, a protocol for whey processing will be established to reduce the heterogeneity among the samples.In order to make real the industrial exploitation of the new disinfection strategy, a commercial formula containing the whey derivatives will be developed. Moreover, the laboratory results will be scaled-up and the most efficient conditions for disinfection of whole and fresh-cut F&V will be defined at pilot and industrial scales. Consequently, the project WHEYSAN will provide two ma
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Virtual building acoustics: a robust and efficient analysis and optimization framework for noise transmission reduction', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Achieving a sufficient sound insulation of buildings is a complex problem since multiple transmission paths are important, uncertainties can have a large effect, and acoustic performance requirements often conflict with structural and thermal requirements. Furthermore, accurate vibro-acoustic modelling across the entire building acoustics frequency range presently requires a huge computational effort. As a result, the acoustic development of building systems is usually based on general design rules, insufficiently accurate prediction models and many experimental prototype tests. Such development is costly and time consuming, and leads to suboptimal designs. This project therefore aims to develop an efficient yet sufficiently accurate prediction framework for the acoustic design of building systems which takes all uncertainties into account and which opens the way for design optimization. Four fundamental breakthroughs are required. First, a new approach to high-frequency subsystem modelling will overcome the limitations of the current statistical energy analysis paradigm and handle a high degree of geometric and material complexity. Second, a modelling framework for built-up systems will be developed, which incorporates different component model types and which switches between them as the frequency increases. The third development consists of quantifying the combined effect of all uncertain parameters on the overall sound insulation performance in a logically consistent and computationally efficient way. Finally, a robust optimization approach that spans the entire building acoustics frequency range and that accounts for all relevant non-acoustic performance criteria as well will be developed. Each development will be complemented by showcase applications in building a