RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Quantum Hamiltonian Complexity'.

assistant: **Objectives**

Quantum computation suggests a revolution in technology and in cryptography, a completely new perspective on the foundations of theoretical computer science, and a different approach to the study of physical systems.One of the major new developments in quantum computation over the last few years has been the emergence of a new field called ``Quantum Hamiltonian complexity (QHC)'', which sits on the boundary between computational complexity theory and condensed matter physics. This direction investigates computational aspects of physical objects such as ground states and Hamiltonians, using techniques from both physics and theoretical computer science. This direction has already hadan immense impact on both quantum computation and condensed matter physics.This project aims not only to investigate  fundamental questions in quantumHamiltonian complexity as it exists today, such as quantum states generation, tensor network descriptions of quantum states, area laws, and the complexity of Hamiltonians, but also to greatly broaden the scope of this new paradigm, into the study of quantum PCP; into new frontiers in quantum algorithms such as quantum walks, adiabatic algorithms and topology and tensor networks related algorithms; as well as into the study of quantum protocols such as coin flipping, quantum interactive proofs and quantum cryptography and their implications on our understanding of quantum entanglement.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Resolving short-distance physics mechanisms in hadron collisions at TeV-scale energies' (PROBE4TeVSCALE) targeting Seventh Framework.

assistant: **Abstract**

The Large Hadron Collider (LHC) at CERN offers a promising opportunity to discover and characterize a putative new physics sector at the TeV energy scale. Due to the complexity of the experimental signatures, the direct search for new particles at this huge experimental facility is a real challenge, requiring a very clear understanding of the structure of hadron collisions. For this reason, in the last decade a tremendous effort has been devoted  to improving the accuracy of theoretical scattering amplitudes. Very recently,  a new milestone has been reached with the elaboration of algorithms capable of generating hard scattering amplitudes at next-to-leading-order accuracy. In this context, it is urgent to redefine strategies for new physics searches at the LHC which makes maximum use of state-of-the-art theoretical information.In this project, we consider more specifically the  case of decay chains, which plays a very important role in the search for new physics. As a first objective, we propose to use our expertise in Monte Carlo techniques, spin physics and next-to-leading-order calculations to develop a generic decay algorithm designed specifically to retain all spin correlation effects at next-to-leading order accuracy in any decay chain in the Standard Model and beyond, and to implement this algorithm in the MadGraph framework. Secondly,  we propose to develop a matrix-element-based likelihood method dedicated to experimental analyses involving decay chains and constructed to maximize the use of spin correlation effects. Finally, we propose to revisit, with the aid of these tools, specific searches for new physics at the LHC -in particular the search for a light Standard Model Higgs- and to assess the increase of significance that is gained with a careful treatmen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Advanced Cavities Using High Resolution Additive' (ACUHRA).

assistant: **Concept**

The work will focus on the use of additive manufacturing to produce lightweight innovative components to for swirl control to facilitate the design of more efficient low pressure turbines.  The Consortium’s predominant aim is of delivering key technical advancements to the EU aerospace sector that will advance the knowledge and control of flow in LPT seal cavity geometries.   This will be achieved through the use of high fidelity CFD, combined with novel optimisation, additive design and manufacture.  A comprehensive experimental verification program will also evaluate experimentally the concept designs and provide a substantiated appraisal of concepts.


**Keywords:** computational fluid dynamics, low pressure turbine, additive manufacturing, aeroengines
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Precision mass spectrometry to leverage applications in life and environmental sciences' (Precision4Life), addressing dissemination and exploitation.

assistant: **Impact**

The unbeatable performance leaders in molecular analysis of biological and environmental samples are the Fourier transform mass spectrometers (FTMS): Orbitrap FTMS and ion cyclotron resonance (FT-ICR MS). However, even FTMS approaches suffer from performance limitations when facing the molecular complexity of samples in modern applications. The primary reasons for these limitations are the space charge effects – strong Coulombic interactions of many ions oscillating in the trapping devices. Applications suffering from space charge affects include those with (i) significant fluctuation of incoming ion currents; (ii) close spacing of molecular mass/charge ratios to be resolved; and (iii) high spectral dynamic range of ion intensities. To address these performance challenges and as a result of the completed ERC Starting Grant, we propose to increase precision of mass measurements in FT-ICR MS by using the direct cyclotron frequency measurements instead of the space charge-sensitive reduced cyclotron frequency measurements employed currently. We have confirmed the principal feasibility of FT-ICR MS at the cyclotron frequency on both types of commercial FT-ICR MS instruments on the lab level. The aim of our PoC grant application is to realize the benefits of FT-ICR MS at the cyclotron frequency by developing and seamlessly integrating the laboratory-level innovation into commercial instruments at an industry-grade level to leverage life and environmental sciences applications. The action plan includes: (i) enabling integration of prototype ICR mass analyzers into commercial FT-ICR MS instruments via feasibility studies and pilot projects; (ii) analyzing competitive advantages of the project’s outcomes over existing products and workflows, with a focus on frequency (mass) pre
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'High performance Production line for Small Series Metal Parts' (HYPROLINE), addressing dissemination and exploitation.

assistant: **Impact**

The general objective of Hyproline is to strengthen the competitiveness of the European industry by introducing manufacturing methods, which will allow companies to 1) reduce time-to-market and number of rejects, 2) make more customized and innovative products with a higher market value, and 3) make products > 20% more accurate with considerable savings (>30%) in consump-tion of waste metal, fluids and services, with an equivalent reduction of CO2 emission.By further developing the manufacturing process itself as well as by research and application work on materials, pre and post treatment of the parts produced and supporting software Hyproline adds capabilities to commercially available manufacturing systems, in terms of speed, product quality and versatility.By keeping focus on the entire process from conceptual outline of the product via product design, engineering and production planning to actual manufacturing and control of quality, the project contributes to the development of a versatile manufacturing process, suited for industrial produc-tion by SMEs of complex custom made metal (meso scale = order 10 mm) parts in small batches or even in one-of-a-kind production mode.The Hyproline manufacturing concept will be demonstrated by its pilot implementation forserial production of customized high quality meso parts for two different industrial sectors of (1) electronics and (2) aerospace.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Interference Management Techniques for MultiCell Wireless Networks' under Seventh Framework.

assistant: **Concept**

Future wireless communication systems should provide a wide range of services at a reasonable cost and sufficient quality of services (QoS), comparable to wireline technologies. In order to satisfy these requirements, the spectral efficient wireless cellular networks can be designed by reducing the frequency reuse factor to unity. However, it is well known that aggressive channel reuse generates intolerable intercell interference (ICI) and affects the overall network performance. The development of methods that handle the tradeoff between the spectral efficiency and ICI is still an open problem. For this purpose, the management techniques for cellular networks beyond the existing/traditional ones should be developed by taking into account the effect of ICI. The interference can be exploited to improve the reliability/spectral efficiency with cooperation between base-stations and/or users through backhaul and feedback links. The objective of this project is to study the performance of future wireless networks exploiting cooperation between the cells in a realistic environment by using both analysis and evaluations through practical scenarios. Apart from the traditional cellular arrangements, we will focus on interference management strategies including distributed implementation of the precoding algorithms; combination with radio resource management issues to manage users’ satisfaction having different QoS and design feedback strategies to establish cooperation/coordination between base-stations and/or users. The project addresses the development of interference management strategies and intercell scheduling/allocation techniques to improve the cell throughput by employing capacity constraint backhaul link. The impact of channel estimation uncertainties, and synchronizat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Bacterial-Derived Therapeutics based on CircRNAs (BacTheRNA)' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

RNA therapeutics are a rapidly growing field of research, thanks to their enormous potential. However, production costs and delivery systems represents the major issues for their widespread use in clinics. BacTheRNA aims at overcoming these issues by developing novel circular RNA (circRNA)-based therapeutics using recombinant food-grade bacteria. CircRNAs are advantageous over their linear counterpart, for their stability due to their intrinsic resistance to nucleases (which cannot cut circular molecules without free ends). Their production costs are thus lower, as they do not need chemical or enzymatic modifications. Moreover, production in bacteria is simpler than chemical synthesis and it is scalable, with further reduced production costs. CircRNAs will be either purified as naked molecules or will be directly secreted by the bacteria in extracellular vesicles (EVs) embedding targeting moieties. Importantly, non-immunogenic circRNAs can be designed. Intriguingly, BacTheRNA will demonstrate that it is possible to include targeting moieties directly through programming of circRNAs natural packaging, i.e. by expressing appropriate surface ligands on recombinant EVs. Finally, the potential to reach increased efficiency thanks to the possibility of amplification through rolling circle mechanisms is yet another innovative aspect of these next-generation RNA therapeutics.As a proof-of-concept, circRNAs produced in BacTheRNA will be applied to Type 2 Diabetes Mellitus (T2DM) as a model target disease. Nevertheless, BacTheRNA will demonstrate a general strategy, which can potentially be exploited in several other pathologies that may benefit of RNA therapeutics approaches.


**Keywords:** CircRNA, bacteria, RNA therapeutics
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Pushing Gold beyond its common redox states'.

assistant: **Innovation**

The chemical elements are central to chemistry, physics and biology. Exploring their different states and chemical bonding is thus of utmost importance. Yet, 150 years after Mendeleev recognized periodicity in the structure and properties of the elements, there is still much to discover and exploit. Indeed, some elements are still confined to a few oxidation states. This is especially true for gold which, despite major progress over the last decades, lags well behind the other transition metals. At the molecular level, only Au(I) and Au(III) complexes are known essentially.The aim of Gold-Redox is to expand the chemical space of gold to other oxidation states that remain curiosities or are simply unknown. The bottleneck to overcome is to force gold outside its comfort zone. To this end, I will play with ligand design. I will identify ligands that enable gold to accommodate new oxidation states. Gold complexes in unprecedented forms, from Au(0) to Au(IV) and Au(V), will be designed, prepared and studied. Because of their peculiar electronic structures, these new oxidation states will open novel reactivity paths at gold. Most appealing are single-electron processes and Au(III)/Au(V) cycles.Targeting new oxidation states and reactivities, Gold-Redox is inherently very exploratory and cutting-edge. To address this high risk-high gain challenge, I will capitalize on my expertise in highly reactive species and gold chemistry. Ligand design (I previously used to create unusual bonding situations such as with -acceptor ligands, and to emulate unprecedented reactivity of Au(I)/Au(III) complexes) will be central, as well as thorough structure-properties analyses by advanced experimental and computational methods. Gold-Redox will provide in-depth fundamental knowledge on novel gol
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Creating a new paradigm of business value creation by fostering collaboration and data sharing while minimising the cost of business transformation' (DEMS-Nixus), addressing dissemination and exploitation.

assistant: **Impact**

In order to keep competitive, companies need to integrate large volumes of data from multiple disparate sources and return insights immediately. The current approach to the digital transformation is based on fragmentation: isolated and customised tools for different areas of the organisation. In today's complex and fast changing environment, this approach is no longer effective to manage business strategies and objectives due to: 1)lack of integration, 2)lack of interoperability and collaboration, 3)large time-to-value, 4)high costs, and 5) lack of transparency. Managers end up taking gut-feel decisions instead of data-driven ones.Global Data Excellence (GDE) brings DEMS-Nixus, the only complete solution for automated Data Integration, Data Cleansing, Business Intelligence, Data Governance and Data Sharing. The platform is the first end-to-end solution able to process natural language with no deployment or programming effort from the client side. DEMS-Nixus drastically accelerates the speed of business value creation (from 3-6 months to 3 days) minimising the cost of business transformation by 80%.GDE operates on the B2B market through a SaaS model. GDE is planning to sell two initial packages: the DEMS-Nixus basic software and the Data Excellence Framework (optional package with additional services). The pricing model will be completed with a yearly-fee license that depends on the number of 1) defined business rules, 2) unique records, and 3) domains.DEMS-Nixus will be introduced first in the markets where GDE is operating already. Existing clients have shown interest in the new product and will act as early adopters of the technology. Afterwards, DEMS-Nixus will start the expansion to other European markets, US and Canada.DEMS-Nixus represents a real innovation for th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Relating core-mantle interactions and the geomagnetic field' (CORE-MANTLE-BR) targeting Sixth Framework.

assistant: **Abstract**

The geomagnetic field is generated by fluid flow in the metallic liquid outer core, a process known as the geodynamo. Due to its current strength and mainly dipolar geometry, this field efficiently organizes the way particles flow in the vicinity of the Earth, preventing them from directly reaching the atmosphere. Currently however, the geomagnetic dipole decays 10 times faster than the free decay rate. Understanding the mechanisms responsible for this rapid evolution is then both a practical issue - predicting the future morphology of the magnetosphere and areas of danger in space - and a fundamental one - understanding the inner working of the geodynamo.This proposal aims at studying the possible influence of core-mantle interactions in defining the main characteristics of the current geomagnetic field, and the mechanisms governing its evolution. To achieve this, we will combine geomagnetic data analysis, dynamo simulations, and seismic imaging. Such an approach is now accessible for extensive studies, thanks to the availability of more and more high quality geomagnetic and seismological observations, and of much more affordable numerical dynamo codes. Geomagnetic secular variation (SV) data will be inverted for flow models below the core-mantle boundary. Lower mantle tomography data will be used to infer density anomalies and mantle-driven thermal wind flows at the top of the core. Numerical dynamo simulations will be used to model core flow driven by convection at the outer core.Comparisons between all those flow models will be used to infer mantle control on core flow. Geomagnetic data and core flow models will otherwise be used to compute contributions of meridional advection, radial diffusion and meridional diffusion to the decrease of the geomagnetic dipole mome
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Desynchronizing weak cortical fields during deep brain stimulation', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Deep brain stimulation (DBS) is a surgical treatment for Parkinson’s disease and other neurological disorders. By applying pulsed, alternating electric currents to targets deep in the brain, DBS induces widespread changes in neural network activity. Although motor symptoms can be reduced by DBS in most patients, some patients suffer from severe side effects or insufficient symptom relief.Many attempts have been made to optimize the therapeutic effects of DBS, but these attempts have been restricted by a lack of understanding of how DBS exerts its therapeutic effects. Various therapeutic mechanisms have been proposed, but none have fully explained all of the complex effects of DBS. These theories have focused on direct and indirect effects of the strong electric fields near the stimulation contact.I propose a radically new hypothesis on the therapeutic mechanism of DBS that harnesses current insights from noninvasive brain stimulation. Weak electric fields during noninvasive brain stimulation have recently been shown to desynchronize neural activity from the surrounding network activity. I suggest that weak electric fields during DBS desynchronize cortical activity, which can, in combination with the effects of strong subcortical electric fields, reduce pathological synchrony in motor system networks and thereby restore motor control.DECODE will integrate large-scale volume conduction modeling to estimate and steer personalized electric fields, biophysical neural network modeling to understand the physiological consequences of weak fields and their interaction with strong field effects, and EEG measurements in humans to verify these models. Finally, based on the obtained knowledge and computational tools, DECODE will clinically test the hypothesis in patients with Parkin