RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Fundamental aspects of metal speciation and transport in metal - contaminated soils and aquifers.' (1994-1998) under Fourth Framework.

assistant: **Objectives**

The overall aim of the project is: To apply recent developments in the speciation and transport of metals in soils and aquifers to verify predictive models for the long-term fate and transport of metals in metal-contaminated soils and aquifers (here 'metal' includes metalloids such as arsenic). This will improve the scientific basis for assessing the long-term fate and environmental significance of metals in risk assessments. This will be achieved through the following four objectives: OBJECTIVE A (SPECIATION, UK): To develop new field and laboratory methods for measuring in situ trace metal speciation in pore waters from metal-contaminated soils and aquifers. The pore water chemistry of water displaced from field-moist soils and aquifer materials will be measured and the free metal ion concentration measured using a novel approach (the Helmke method). OBJECTIVE B (CHARACTERISATION, FR): To characterise the physicochemical properties of metal-contaminated soils and aquifer materials that control metal solubility. The soild and surface chemistry of the soils and aquifer materials will be related to the composition of the pore water measured in Objective A. OBJECTIVE C (MODELLING, NL): To develop methods and modelling methodologies for predicting the solubility, speciation and transport of metals and dissolved organic carbon (DOC) in metal-contaminated soils and aquifers. A model for the release of metals and DOC for metal-contaminated soils and aquifer materials will be developed. OBJECTIVE D (TRANSPORT, CH): To use laboratory column studies to verify transport models in contaminated soils and aquifers and to explore soil and aquifer treatments on metal mobility. Metal breakthrough and leaching experiments will be conducted under a wide range of experimental conditions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'enabled Dynamic Air Traffic Flow Configuration for Flow-Centric Airspace Management' (DeepFlow) under Horizon Europe.

assistant: **Objectives**

Facing the air traffic growth and the challenges in balancing air traffic between geographical sectors, the air traffic control paradigm is shifting from local sector-based solutions to cross-border flow-based approaches. Such flow-centric approaches can be promising to overcome the scalability limits of geographical sectors and optimize the traffic at a regional level. Under this paradigm, this project proposes to develop a dynamic air traffic flow configuration method to assess, predict, manage, and optimize the evolving air traffic flows to enable more efficient flow-centric ATFCM and airspace management. To realize this, first, a flow-pattern extraction module will be developed to identify the major air traffic flows and to characterize the traffic flow structure. Second, with the identified traffic flow pattern, a flow monitor module will be developed to observe the evolution of major traffic flows, such as flow density, flow rate, and flow interactions, integrating as well weather and environmental impact key performance indicators. Third, with the monitored traffic flow data, a traffic flow assessment module will be designed to measure the congestion and flow/capacity imbalance in the airspace, followed by a flow prediction module to provide forecasts of the future air traffic flow features. The fifth module, traffic flow configuration, will investigate the dynamic flow management strategies, such as flow merge and split and flow regulation, based on the flow assessment/prediction outcome. This last module will allow for installation of Flow Regulation Gates to monitor flow interactions and to regulate flights according to flow capacity. An integration of these modules into a flow-centric airspace management framework can pave the way to the dynamic airspace mana
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Vegetation and urban air quality: CFD evaluation of vegetation effects on pollutant dispersion' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Air quality in the urban environment is gaining increasing attention by city authorities and residents due to rising urbanization and growing individual traffic. One important aspect in today's urban design and planning is to make cities favorable for the natural ventilation enabling a fast dispersal and removal of air pollutants emitted by traffic and buildings. Green spaces play an important role in these considerations as they may enhance, e.g. by wide open parks, or inhibit, e.g. by avenue-like tree plantings in urban street canyons, the natural ventilation.The influence of vegetation on pollutant dispersion and concentrations in the urban environment will be investigated by Computational Fluid Dynamics (CFD) employing Reynolds-averaged Navier Stokes (RANS) turbulence models and Large Eddy Simulations (LES). A central point in this research project is to develop new parameterizations (vegetation modules) accounting for the effects of vegetation on flow and turbulence characteristics. The CFD simulations will be evaluated against available wind tunnel data, e.g. the CODASC database (Concentration Data of Street Canyons, www.codasc.de), wind tunnel studies to perform at collaborating institutions and full scale experiments in the Dutch cities of Arnhem and Nijmegen (leader of these street case studies: Dr. ir. Bert Blocken, TU Eindhoven, period 2011/12).The project's outcomes will strongly contribute to an improved air quality modelling in the urban environment by taking the important implications of vegetation on flow and turbulence characteristics into account. CFD simulations are becoming gradually more important in urban air quality modelling with increasing computer performance in the next years. Therefore, validated CFD models with vegetation modules will become
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Symmetries and Spectra'.

assistant: **Objectives**

Symmetry is ubiquitous in nature. It is a fundamental concept and organising principle in quantum field theory, the common language of modern theoretical physics. The past few years have witnessed a radical evolution in the notion of symmetry that transcends the paradigm of groups and representation theory and marches into the realm of higher mathematics. This is known as categorical symmetry. The field has experienced a period of rapid discovery and exploration but the underlying mathematical structure remains poorly understood and this hinders progress on the most pressing open problems. Now is the time to take stock of recent developments and establish new mathematical foundations and computational tools in order to take advantage of this unprecedented opportunity to explore novel symmetries and gain new insights into physical systems described by quantum field theory.The purpose of this research programme is to establish a coherent mathematical framework for categorical symmetry. The research programme introduces and explores the notion of ``categorical spectrum"", which compiles topological quantum field theories of all dimensions into a mathematical structure that opens up powerful conceptual and computational advances. This is applied to the exploration of categorical symmetries, 't Hooft anomalies and gapped phases of matter, catalysing a step change in the discovery of new examples and applications.""


**Keywords:** Symmetries, Quantum Field Theory
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Water-based solutions for carbon storage, people and wilderness' to be submitted under Horizon 2020.

assistant: **Abstract**

WaterLANDS aims to enable an upscaling of the restoration of wetlands. Socio-economic factors, insufficient stakeholder engagement, lack of government commitment, lack of funding and inadequate exchange of knowledge of restoration methods have all been identified as barriers to successful restoration. Consequently, most restoration has been modest in scale, has occurred mainly where there is a single landowning or responsible organisation, and has often been undertaken principally for reasons of conservation. WaterLANDS will work to overcome these barriers. It includes both Action and Knowledge Sites, the former being the object of restoration upscaling, and the latter a source of best practice experience and knowledge. To provide for local support and sustainability, it will aim for the co-design of restoration with the on-going engagement of communities and stakeholders. It will investigate best practice in ecological restoration which meets both biodiversity and social objectives and for which restoration trajectories are specific to the physical and cultural context of the Action Sites. It will propose supportive governance structures appropriate to this process and to local and national circumstances. It will identify business models, economic incentives and international funding sources and tailor or direct these resources for each site. The project will pull this expertise and knowledge together in a co-creation work package. Process-indicators will be developed to enable on-going assessment of restoration success in terms of ecosystem services, socioeconomic embedding and financial sustainability, to ensure wide-scale restoration which catalyses scalability beyond the life of the WaterLANDS project.


**Keywords:** Co-creation, Just Transition, Financial Mechani
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Harnessing natural killer cells to combat chemotherapy resistance' under Horizon Europe.

assistant: **Concept**

Chemotherapy resistance remains a major challenge in cancer treatment, often leading to poor patient outcomes. NatK aims to (1) identify predictive signature of chemoresistance and (2) develop innovative therapeutic strategies to overcome it, using triple negative breast cancer (TNBC) as a model. The focus is on natural killer (NK) cells, hypothesising that reactivating these cells could enhance their cytotoxicity against chemoresistant tumours.  State-of-the-art 10X Visium spatial transcriptomics will be employed to analyse primary TNBC samples from chemotherapy responders and non-responders, mapping NK cell infiltration and activity within the tumour microenvironment (TME). Advanced bioinformatics will identify immune-related signatures of chemoresistance, validated in independent patient cohorts to develop a robust NK cell-related biomarker for patient stratification. To translate these findings into therapeutic strategies, specific genes upregulated in chemoresistant tumours will be targeted to enhance NK cell-mediated cytotoxicity. Co-culture systems with NK cells and patient-derived organoids will be used to evaluate the impact of gene modulation, followed by the development of small molecule inhibitors targeting promising candidates. The efficacy of combining NK cell activation with chemotherapy will then be assessed both in vitro and in vivo, aiming to establish a novel combination therapy to combat chemoresistance. NatK integrates state-of-the-art spatial transcriptomics, functional immune profiling and patient-derived organoid models to elucidate chemoresistance mechanisms. The insights gained may have broader implications, potentially extending to other cancer types and guiding targeted immunotherapy development. In line with the MSCA Postdoctoral Fellowship
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Complex chemical reaction networks for breakthrough scalable reservoir computing' (CORENET) targeting Horizon Europe.

assistant: **Abstract**

The brain is the world’s most amazing computer and it runs entirely on chemical reactions. The vision of CORENET is to construct brain-mimicking computing devices that utilise networks of chemical reactions as molecular information processing systems. To achieve this vision, we will implement reservoir computing (RC) on microfluidic chips using chemical reaction networks (CRNs) that convert input feedstock molecules and environmental conditions into a pattern of product molecules. This pattern can be monitored on a chip using a combination of high-throughput mass spectrometry analysis, algorithmic cheminformatics and AI tools.  CORENET will generate a breakthrough in highly scalable and functional chemical RC by integrating our partners’ new knowledge and state-of-the-art methodologies in systems and analytical chemistry, microfluidics, cheminformatics and machine learning. CORENET will produce microfluidic chip devices that perform high-level computing with molecules, synthesising and analysing a pattern of output molecules in situ. This molecule-based computing power enables truly sustainable AI and speaks the language of living systems, which constantly process information about their molecular environment. Future applications of our chemical RC system lie in implantable devices, brain-machine interfaces and personalised medicine. CORENET brings together 4 leading scientists with complimentary expertise that covers all fundamental aspects of this project. Their expertise is combined with the world-class knowledge in AI/ML modelling of a high-tech global industry partner with unique research and computing infrastructure, while an SME specialised in the communication and dissemination of results will ensure maximised impact. Our highly interdisciplinary team will gener
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Human-animal interactions in early sedentary and urban societies in the Near East and northern Africa: microarchaeology of livestock dung'.

assistant: **Concept**

Livestock dung is commonly found in many human settlements, especially after the domestication of herds. Although receiving increasing attention in archeology, dung materials and secondary products are still routinely overlooked and this area of research is under-developed despite their worldwide importance as suppliers of manure, fuel source, temper and building material. This oversight is due in part to methodological problems in identifying dung during excavation and many bulk analyses, which destroy critical evidence on dung form, content, deposition and preservation in archaeological assemblages. This research will develop new interdisciplinary analytical strategies for microarchaeological study of dung combining geoarchaeology, bioarchaeology and biochemistry and experimental and ethnoarchaeological approaches. This integrated methodology will be applied to examine the context and content of livestock dung from mobile hunting-gathering to more sedentary farming Neolithic case-studies selected on a transect through the Near East, one of the key heartlands in which plants and animals that were later domesticated occur naturally, to the still little investigated northern Africa, a potentially critical area with implications for surrounding areas including the Mediterranean and the Sahara. It will also provide exciting new insight into the role of livestock and livestock dung in the development of more complex urban societies in Eastern Maghreb. These case-studies offer rich dung evidence for tracing human-animal interactions in different regions through time and key episodes of environmental and social change. The proposed project will establish a standard state-of-the-art interdisciplinary methodology for insight into archaeological dung as a valuable source of info
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Enhancing economic impact in SME's in Romania by building innovation management capacity' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The objectives of this proposal are the following:Increase efficiency and effectiveness of innovation processes of local beneficiaries of SME instrument and SMEs with significant innovation activities and high potential for internationalisation;Facilitate SME’s access to consulting services for innovation management to address bottlenecks to creation of economic impact;Support innovative SME’s to raise the company’s profitability and competitiveness on international markets.Partners deliver 2 specifically targeted service packages and base their approach on complementary experience and know-how as EEN members.The proposal also includes a general management WP consisting of coordination,communication,dissemination and quality check measures.The WPs dedicated to SMEs consist of preliminary steps (customer identification and approach, meetings), assessment of needs and gaps (specific questionnaires based on CEN/TS16555-1 Standard),assignment of innovation experts and lead coaches and supply of tailored services or facilitation of SME-coach interaction.The proposal addresses challenges such as lack of investment in research, lack of innovation management systems,insufficient supply of innovation services,unaffordable market prices.The scope of the project is to eliminate the barriers for SME innovation by supplying 7 days services.Taking account of the ongoing global crisis, innovation process from idea generation to innovation result but also leadership, management skills and other enabling factors like the ability to cooperate with third parties are considered an essential driver for development and economical recovering. The crisis is depressing investments in innovation as the first costs to be cut and particularly SMEs are concerned by this as they do not have internal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Nanofluidics for label-free detection of exosomes and protein aggregates in neurodegenerative disease research'.

assistant: **Objectives**

Microfluidics have become a powerful tool in biotechnology and life sciences, whereas the nanofluidic regime remains widely unused in industry and the clinical environment. Especially protein misfolding diseases such as Alzheimer’s, Parkinson’s and Huntington’s disease, recently experience a growing demand for single-molecule detection capabilities, as the assembly process of a single corrupted protein is correlated with its aggregation propensity and spread of the disease. Conventional microfluidic methods to study relevant biomarkers and aggregates involve fluorescent labelling, which alters the samples' properties and puts additional constraints on experimental design. We therefore seek for methods to study macromolecules (in particular: exosomes, oligomers) in a label-free manner in solution without chemically altering their properties.To overcome this limitation, the project combines innovative nanofluidic technology with cutting-edge label-free microscopy techniques. First, hybrid 2-photon lithography is used for the scalable cost-effective nanofabrication of nanofluidic polymer chips. Secondly, these chips are then employed for the detection and sizing of exosomes (<100 nm) and alpha-synuclein protein aggregates (<12 nm) in solution using label-free imaging methods (e.g. QPM and DUVM).The approach presented here, allows protein misfolding researchers to study oligomerization more efficiently by running orders of magnitude more experiments with same already limited material, and greatly increases availability of nanofluidic chips for protein metrology in existing biological laboratories. New expertise, excellence, management skills and scientific training acquired during the action, prepare the researcher for a role as independent dementia research group leader in