RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Research network for market based instruments for sustainable development.' (1994-1998) under Fourth Framework.

assistant: **Objectives**

To enable coordination between researchers working on market based environmental policy instruments in Europe; to improve the interface with the policy process; and to provide a holistic assessment of the properties and limitations of Economic Instruments for the purpose of environmental regulation.OBJECTIVES: To enable coordination between researchers working on market based environmental policy instruments in Europe; to improve the interface with the policy process; and to provide a holistic assessment of the properties and limitations of Economic Instruments for the purpose of environmental regulation. DESCRIPTION: The Concerted Action proceeds through: i) plenary meetings to set policy, assign responsibility, and review progress; ii) theme groups to establish the state of the art, tracing the implications for the policy process and for further research; iii) workshops and conferences to disseminate the findings, with specific reference to the policy process; iv) synthesis and a comparison of research objectives, results and methods; v) publication and dissemination of the insights for and from the policy process; vi) an Independent Review group which comprises researchers and policy users and evaluates progress during the research. Specifically the state of the art is presented, the lessons from research distilled, the opportunities for synergy identified, and the implications for environmental and broader economic (including employment) policy and further research developed in the following areas: i) Types of Instrument - Voluntary agreements, the assignment of property rights, tradeable permits, the integration of regulation and market-based instruments; ii) Implementation Issues - Transaction costs, innovation and costeffectiveness in application, Political Econo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Imaging light evoked activity at different strata of the mammalian retina' (RETACTIVITYIMAGING).

assistant: **Concept**

The mammalian visual system analyzes the world through a set of separate spatio-temporal channels. The organization of these channels begins in the retina where the precise laminations of both the axon terminals of bipolar cells and the dendritic arbors of ganglion cells form a vertical stack of neural strata at the inner plexiform layer. A major challenge is to understand how the different ""visual features"" extracted by different retinal ganglion cell types are computed by each, ganglion cell type specific, circuitry at different depths in the inner plexiform layer. My specific research aim is to use in vivo electroporated, genetically encoded fluorescent activity reporters in subtypes of inner retinal cells to image in real-time the patterns of light evoked activity at the dendritic or axonal processes of the labeled cells using two-photon microscopy. My goal is to understand the ""rules"" of local activities in different strata of the mammalian inner retina.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Measuring experienced disease burden (ExpBoD): estimating the socio-economic, psychological, healthcare and welfare impacts of diseases' to be submitted under Horizon 2020.

assistant: **Abstract**

The aim of this project, Measuring Experienced Disease Burden (ExpBoD), is to deliver a proof of concept to systematically measure disease impact across multiple non-health dimensions (e.g., economic, psychological impacts) and diseases using Denmark as a testing ground. As seen during the coronavirus pandemic, governments worldwide are expected to manage not only the disease burden of COVID-19 but its impact beyond health. Yet, existing metrics on measuring population health, such as deaths, prevalence, disability- and quality-adjusted life-years (DALY and QALY) do not capture aspects beyond health, and current methods are not equipped to systematically estimate multiple non-health disease impacts across diseases. I will systematically estimate the disease impact across five dimensions: economic, social, psychological, physical, and healthcare and welfare impacts. ExpBoD will (1) assess statistical methods to identify the most appropriate methodology, (2) systematically estimate disease impact across dimensions and diseases, conduct sub-group analyses, and (3) create a composite index for experienced burden. By providing a comparable metric of broader aspects of disease burden, this research will advance the literature in health metrics and improve the evidence base for priority setting in the real world. The unique opportunity that the fellowship provides will allow me to build this long-term and policy-relevant research agenda and propel me into a successful future academic career.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Innovations to accelerate vaccine development and manufacture' (Inno4Vac) targeting Horizon 2020.

assistant: **Abstract**

Inno4Vac proposes an ambitious programme that will harness the latest advances in immunology, disease modelling, and modelling for tackling persistent scientific bottlenecks in vaccine development and for de-risking and accelerating this process. To reach this aim the project is divided into  four interlinked subtopics. In Subtopic 1, artificial intelligence in combination with big data analysis and computational modelling will be used to build an open-access and cloud-based platform for in silico vaccine efficacy assessment and development. Subtopic 2 will develop new and improved controlled human infection models (CHIM) against influenza, RSV and C. difficile that will enable early vaccine efficacy evaluation. Subtopic 3 will contribute to the development of cell-based human in vitro 3D models that resemble the in vivo situation of an infection at the mucosa and more reliably predict immune protection. These models will be combined with the development of related functional immune assays for clinically relevant (surrogate) endpoints. Finally, Subtopic 4 will develop a modular one-stop computational platform for in silico modelling of vaccine bio-manufacturing and stability testing. In parallel to the scientific-technical work, the partners will develop strategies and roadmaps for positioning the newly developed models in the regulatory framework and integrating them into pharmaceutical vaccine development. The overall workplan is underpinned by horizontal activities on coordination/management and dissemination/communication, including data management and future sustainability.To achieve these ambitious objectives, Inno4Vacc has assembled a multidisciplinary consortium from academic and research institutions, industries, regulatory bodies, and vaccine R&D alliances. Th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Weather forecasts for proactive short-term AGRicultural climate change ADAPTation' (AGR-ADAPT).

assistant: **Innovation**

Because crop growth is directly dependent on climate, the agricultural sector is arguably the most climate-vulnerable sector. Extreme weather events (EWE), worsened by climate change, can severely impact yields. Climate adaptation is crucial to mitigate this damage. Although most research has been done on long-term adaptation (i.e., farm measures taken in response to long-run climate change) farmers can take short-term measures in response to forecasted EWEs to reduce weather-induced damage. The 2023-27 Common Agricultural Policy dedicates inadequate attention towards this type of adaptation. Rather, it encourages the uptake of insurance to cover weather-induces losses subsidising insurance premiums. This project aims to gain insight into the adoption of proactive adaptation based on forecasts, its economic benefit and its complementarity to weather insurance in order to advise policymakers on a subsidy allocation which is in line with the Farm to Fork Strategy, which pursues a more resilient agricultural system.The research will involve a comprehensive assessment of how EWEs, as defined by insurers’ weather indices, impact farm economic performance. It will provide an in-depth analysis of how farmers use weather forecasts to proactively adapt. The project will also evaluate the economic value of these proactive measures in reducing the impact of EWEs. Finally, the project aims to disseminate these findings to policymakers. The project will employ a mix of qualitative and quantitative methods, including literature reviews, stakeholder interviews and econometric analysis, focusing on European horticulture and permanent crop farms.The researcher, aspiring a senior research career with expertise in the economics of climate adaptation, will gain significant scientific exper
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Intelligent mini bioreactor - a machine to process tissue engineered implants' (IMBIOTOR).

assistant: **Concept**

Tissue Engineering is a major focus of biotechnology research today. The most ambitious tissue engineering schemes involve the processing in vitro of cell seeded constructs to induce the formation of neo-tissue through the utilisation of bioreactor technologies. The aim of this project is to develop a prototype intelligent integrated mini bioreactor (IMBIOTOR) to improve the efficacy and efficiency of manufacture of tissue engineered implants. The IMBIOTOR will support fully or semi-automated operation and maintenance of a closed aseptic environment during tissue processing. It will incorporate intelligent control and novel monitoring systems for biological output and the relevant feedback mechanisms necessary to provide optimum stimulation of neo-tissue formation. These objectives will be achieved through a multidisciplinary, multinational approach, with the aim of introducing the novel process into the emerging industry of tissue engineering.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Improved Millets for Phosphate ACquisition and Transport'.

assistant: **Innovation**

Phosphorus is an essential plant nutrient and is limiting for crop yield on up to 40% of arable land worldwide, including Europe. The major scope of current proposal is the exploitation of strategies to improve the phosphate use efficiency of a key crop, foxtail millet (Setaria italica). Several families of membrane transport proteins are involved in the uptake of Pi from soil and its distribution within the plant. These transport proteins are referred as Pht1. In this study we propose to characterise the Pht1 family of Seteria italica and determine whether manipulation of expression level or affinity for substrate is a useful approach for improving phosphate use efficiency. Molecular approached involved in this study include gene expression studies of the phosphate transporter (Pht1) family from foxtail millet (Seterica italica), construction of a homology models of all expressed SiPht1genes, down regulation of the major low P inducible root and shoot transporters by RNAi, cloning the most significant members of this family and confirm their function by expression in heterologous systems. Site directed mutagenesis guided by the homology model will also be performed to identify important residues. Finally, millet will be transformed with wild type and selected mutants and tested for the performance on different phosphorous regimes. This study underpins the efficient phosphate usage in foxtail millet and help to improve the yield in other crops by utilizing the technology""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Manufacturing Error-free Goods at First Time'.

assistant: **Innovation**

Today, Europe’s leading position in manufacturing of high-precision metal parts is being threatened by developed non-EU countries that catch up quickly on product quality at low cost. If no further action is taken, loss of jobs and GDP are at risk.To face global competition, a breakthrough is needed in tackling the following 4 challenges:1)High number of defects2)Many costly, energy consuming finishing operations are needed.3)Continuous trend for higher quality, smaller features, lower costs, at simultaneous demand for customised products.4)Six-Sigma methodology reaches its limits for these complex processes (multi step / customised).MEGaFiT will realise this essential breakthrough.The primary goal of MEGaFiT is to develop and integrate all necessary technologies which create the basis to reduce the number of defects in manufacturing of complex high-precision metal parts. This will be achieved by developing and integrating in-depth process knowledge, in-line measurement and real-time adaptive process control. Proof will be given on pilot production lines in industrial settings.MEGaFiT will do this with a consortium of partners best-in-class in these fields. The methodology that will be used to come to efficient realisation is the following: (1) Define and describe the process (2) Measure actual process performance (3) Identify potential adaptive control solutions (4) Design adaptive control solutions and (5) Verify the adaptive control solution.This methodology will result in reduction of: defects from 5-15% to <1%; cost by >20%; material and energy consumption by >20%; and number of finishing operations by >35%.The knowledge-based MEGaFiT results are also applicable in different sectors, leading to low defects, despite customization trends. MEGaFiT will therefore help
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Reuse of mining waste into innovative geopolymeric-based structural panels, precast, ready mixes and insitu applications'.

assistant: **Innovation**

The construction sector, currently in crises in some countries due to the economic development model adopted during last decades, can again play an important role for the European economy to be more innovative by using fewer resources (raw materials and energy) and reducing environmental impact (emission of greenhouse gases and dust pollution). Access to raw materials and resource efficiency are at the forefront of the EU political debate and recycling is a main part of the solution of many strategic objectives. It addresses resource scarcity and enhances security of material supply, while contributing to higher energy efficiency and lower environmental impacts. Moreover, recycling offers significant investment, innovation and employment opportunities in the EU. In this context, this RISE programme aims to promote international and inter-sector collaboration through research and innovation staff exchanges, share knowledge and ideas from research to market (and vice-versa) for the advancement of science and the development of innovation within the recycling and valorization of mining and quarrying wastes which represent 27% of the EU total waste generated from economic activities and households, promote utilization of innovative geopolymeric materials in the construction sector, and foster a shared culture of research and innovation that welcomes and rewards creativity and entrepreneurship and helps turn creative ideas into innovative products, services or processes in the materials industry through recycling mining wastes, by taking advantage of the integrated knowledge acquired in the complementary areas of the RISE partners. In this scenario, this RISE action aims at taking advantage of the recent developments in the areas of materials science, processing engineering,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Eco-friendly Modification of Bitumen (ECOMOBI) - Recycling end of life tyres into an efficient bitumen modifier' under Horizon 2020.

assistant: **Concept**

Tecnofilm is an Italian SME with 44 years of experience in the thermoplastic industry. Our project, ECOMOBI, was granted the Seal of Excellence label in the last Phase 1 call with a score of 13.28; we have thus decided to resubmit it. Through ECOMOBI we plan to develop an innovative cost-effective eco-compound for the modification of bitumen. Bitumen has a wide range of uses, namely road construction. In order to confer it the necessary characteristics for this use, bitumen is currently modified through the use thermoplastic elastomers. However, these elastomers are expensive and confer low aging resistance, making them even less cost-effective. There is a need for bitumen modifiers that can offer the same quality properties as thermoplastic elastomers, but reducing the cost and increasing the lifespan of the end products.On the other hand, Europe searches to promote solutions for the recycling of tyres. Across Europe, 5.7M tonnes of tyres are stockpiled in landfills, and recently the biggest tyre dump in Europe caught fire, with the subsequent damage to the environment and human health. However, currently only 17% of Europe's end of life tyres are recycled. ECOMOBI brings forward the development of a solution for bitumen modification using end of life tyres: RD PRENE. Through the commercialization of RD PRENE, Tecnofilm would have an annual revenue of 10M € in 2022. Its innovative formulation and extrusion process have managed to match the quality of thermoplastic elastomers. The increased elasticity of the bitumen modified with RD PRENE confers a 50% longer lifespan to end products than current alternatives, reducing the maintenance and replacement needs and derived costs. Moreover, due to the use of tyre powder in its composition, RD PRENE is 57-26% less expensive th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Continental Rifting and Volcanism in the Western Sicilian Channel' (CoRVoS), addressing dissemination and exploitation.

assistant: **Impact**

Understanding the mechanisms of continental rifting is fundamental to the study of plate tectonics. CoRVoS will investigate the relationship between tectonic processes, and magmatism in the Sicilian Channel Rift Zone (SCRZ). Although our understanding of active, plume-associated rifting has been advanced recently, the SCRZ is characterised by passive rifting. A comprehensive regional model detailing how volcanism has developed in this region is lacking, and would generate further understanding regarding to what extent passive rifting is accommodated by magmatism. There are a lack of interdisciplinary studies investigating both the structure and geochemistry of such regions, which is crucial in devising a robust model. CoRVoS proposes to use a unique catalogue of volcanic samples from 22 submarine volcanoes in conjunction with high-resolution bathymetry and structural data, which will be collected as part of a funded research cruise. Whole-rock, mineral, and melt chemistry, thermobarometric models, and textural studies of the volcanic products will allow for the determination of the crustal evolution of magmas. This data will be compared across areas of the rift zone with differing tectonic processes, determined using high-resolution bathymetric data. 40Ar/39Ar geochronology will determine of the age of volcanism, allowing for temporal analysis of magmatic processes. The volcanic activity in this area includes historical submarine eruptions, and four new volcanic edifices were recently discovered off the coast of Southwest Sicily. The hazard associated with these volcanoes, and any tsunamis they may generate, to the densely populated coastal areas of Sicily, the shipping industry and seafloor infrastructure, is currently poorly quantified. CoRVoS aims to assess this risk