RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Qcd matter' in the context of a Fifth Framework call.

assistant: **Objectives**

The main scientific objective of the School is an in-depth discussion of experimental and theoretical aspects of the ultra-relativistic nuclear physics. With RHIC accelerator at Brookhaven National Laboratory, operating with nuclear beams having CMS energy 200 GeV per pp collision, coming into operation, a wealth of new data is expected to be available in the summer of the year 2001. Also, few years from now, LHC accelerator at CERN will work with nuclear beams at still higher energies, 5.5 TeV for lead nuclei. Theoretically a lot of new and exciting phenomena are expected in such ultra-relativistic heavy ion collisions, most notably, the increasingly important role of the deconfined quark-gluon matter created at their early stage. A school such as this is needed due to the rapid increase of the community of young theorists and experimentalists in this field.This school is unique in that we include topics relevant to both high-energy nuclear collisions and high-energy electron-hadron physics. There is much overlap in both the theoretical and the experimental goals of these fields, but at present, only little overlap of people. The organizers feel strongly that progress in both of these areas will involve interplay of disciplines. The atmosphere provided by Cargese is ideal for the type of interactions we wish to encourage. The intimate setting and relative isolation of the conference place should generate many interactions between lecturers and students. The diversity of nationalities of the students should work for future international collaboration between the young people.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Digital Endocrinology Training Network to combat adrenal diseases', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Digital endocrine medicine is revolutionizing healthcare by integrating technology, data, and personalized treatment, enabling more precise, efficient, and accessible care that disrupts traditional medical models. Advancing digital endocrine medicine to the next level of knowledge and translational value demands an ‘integrative’ approach that departs from the conventional ‘sum of monothematic experts’ towards the ‘merging of multiple themes in one expert’. In this fast developing field, interdisciplinary experts can better communicate across topics as dispersed as clinical medicine, data science (incl. machine learning and artificial intelligence), mathematics, engineering, biochemistry, biotechnology, ethics, law, while adapting academic findings to real word needs. ENDOTRAIN is poised to fill in the gap of interdisciplinary experts needed to advance digital endocrine medicine research and clinical application. This doctoral network joins leading researchers and entrepreneurs from 8 countries to train 15 Doctoral Candidates (DCs), along with 4 DCs funded by Switzerland (SDCs), across different disciplines and sectors. Exceptionally trained in digital endocrine medicine, these versatile DCs will be prepared to face broader challenges beyond endocrinology and become the next generation of clinicians, scientists, and innovators, equipped to enhance Europe’s capacity to navigate the rapidly evolving landscape of digital medicine.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Rate of Adaptation in a Changing Environment', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

For thousands of years, we have been changing the environment that surrounds us to satisfy our needs and to make our life safer, easier and more prosperous. However, we are not alone on this planet and the increasing magnitude of alterations we impose on our environment impacts the biosphere at every level, from bacteria to mammals. Many of these anthropogenic influences may be fatal for those species, leading to extinction and decrease of biodiversity. To avoid that, it is crucial to understand the process of adaptation in the context of a changing environment, and to understand the limits to population persistence.However, rigorous analysis of the adaptive process has been hindered by technical difficulties and our understanding of adaptation in a changing environment is extremely limited.  Therefore, I want to investigate the rate of adaptation in a changing environment from a completely new perspective, enabled by the latest advancements in the field of computer science. The recent establishment of a unified framework of evolutionary processes, bridging the gap between evolutionary computation and evolutionary theory, enables the translation of methods and results between the fields. It has been shown that these techniques can be applied to simple models of biological evolution, and provide new insights into the evolutionary processes. I suggest to employ these methods to analyse the rate at which organisms can adapt to the changing environment.In this project, I will investigate the rate of adaptation, its dependence on natural parameters such as population size and selection strength, and assess the limits to environmental dynamics that can be reconciled with the survival of the species. Knowing the limits to adaptation, the key parameters influencing them and the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Time critical data processing in astronomy' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Marie Curie Postdoctoral Fellows in Time Critical Data Processing and Time Variable Astrophysics. The Astrophysics Research Institute, Liverpool John Moores University, has two vacancies for Marie Curie Postdoctoral Fellows working in the area of timecritical data processing and intelligent agents applied to astrophysical problems. The Fellows will worth in the Liverpool Telescope Development Group of the Institute, where they will be expected to develop software to carry out the following tasks for the Robotic Liverpool Telescope (LT):- Analyze incoming triggers from spacecraft and other ground based facilities and determine a course of action for the telescope.- Rapid and robust pipeline data reduction to determine the properties of targets in near-real time.- Interpret the output of the data pipeline to request follow-up observations with the LT and elsewhere.- Mine remote data archives for data at other wavelengths and epochs. In addition the Fellows will be expected to work with research staff at the Institute on related projects with the LT. These research projects include the optical counterparts of Gamma Ray Burst sources; distant supernovae as probes of cosmology; time critical obsercations of accretion disk systems; pixel microlensing and microlensing searches for planets. The successful applicants will have a strong background in Astrophysical data processing and a research interest in one of the above topics.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Criminal Life-Course Trajectories Globally' (CRIMLIFE).

assistant: **Innovation**

How do social contexts determine paths into crime? How do these trajectories vary across different societal circumstances? And how are they narrated? CRIMEGLO is the first-ever large-scale comparative life-course criminological study globally. No research hitherto has addressed criminal careers and storytelling in such detail and on the scale envisaged in this project. The approach will counterweight the current Northern bias in research and theory, a shift necessary to establish a truly global perspective within life-course criminology.  Cultural and societal contexts play a large role in defining and responding to crime. Social conditions shape the life-courses of those getting caught up in the criminal justice system. Context is also intertwined with the ways people talk about their lives. CRIMEGLO will explore and compare crime from a life-course and life-story perspective spanning four continents and six countries: Norway, the Czech Republic, Türkiye, Nigeria, Bangladesh, and Colombia. By combining criminological theory with institutional, cultural, and narrative studies, CRIMEGLO’s goal is to establish global comparative research on crime within a life-course perspective. The primary objective is to introduce and theoretically develop a contextually sensitive, comparative global life-course criminology. The secondary objective is to achieve a better empirical understanding of the particular social, economic, institutional, and gendered factors shaping criminal life-courses in different countries with highly divergent societal contexts. Principal Investigator Sveinung Sandberg is a sociologist and one of Europe’s leading qualitative criminologists. He has pioneered the prominent research traditions of Bourdieusian Criminology and Narrative Criminology. With CRIMEGL
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The Evolution of Knowledge in the Market for Ideas' under Horizon Europe.

assistant: **Concept**

The Evolution of Knowledge shapes our policy choices. Researchers decide what to research, with whom to collaborate, and how much to invest into discovery. While researchers enjoy institutionalized or implicit scientific freedom, two categories govern the researcher's decision which question to address and how much effort to exert: (i) prior knowledge and (ii) the market for ideas.Prior knowledge is vital to determine how knowledge evolves. Researchers stand on the shoulders of giants and use conjectures derived from previous discoveries when they address problems.  They assess their ex ante prospects on finding an answer by looking at related findings. However, researchers also operate in the market for ideas. Careers depend on how marketable an idea is, how well researchers exploit synergies and complementarities with collaborators, what topics range high on the policy agenda, and what funding opportunities the researcher can access. In sum, how much effort the researcher invests depends crucially on the market for ideas.Our work combines these two aspects and proposes a flexible model to predict the researcher's choice and determine the evolution of knowledge over time. The model is set up with the data in mind to be able to derive meaningful counterfactuals. We can derive implications for designing the market for ideas, e.g., through adapting the funding architecture. We address questions such as: When should funding focus on cost reductions (e.g., grants), when on rewards (e.g., prizes)? When should we push for ""moonshot discoveries"" when for incremental research? Should researchers collaborate with experts on similar topics reducing coordination efforts, or with more distant ones exploiting complementarities? Should we let researchers compete on the same topic i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Photocatalysis as a tool for synthetic organic chemistry' (PhotoReAct).

assistant: **Innovation**

The use of visible light energy to induce chemical transformations constitutes a chemoselective and green activation mode of organic molecules. However, implementation of this energy source in organic synthetic methodologies and in the industrial production of fine chemicals has been challenging. The PhotoReAct Innovative Training Network establishes a training network with 10 beneficiaries from academia and 4 beneficiaries from industry to tackle the challenges associated with photocatalysis in a coherent and comprehensive fashion. In total 15 Early Stage Researchers will be trained within the PhotoReAct network. The network will provide them with opportunities to undertake research with the aim to overcome the current limitations towards the applicability and scalability of photochemical transformations. This will be achieved through rational design of novel photocatalysts, the development of new photocatalytic methodologies, improved reactor technology and direct industrial implementation of photocatalytic transformations. Furthermore, the ESRs will be trained in the PhotoReAct graduate school, acquiring scientific, personal and soft skills. All ESRs will perform three secondments, of which at least one is intersectoral and carried out with an industrial partner and a second is international. Consequently, the ESRs will have improved career prospects and a higher employability. Due to the high degree of industrial participation, the PhotoReAct network will provide an innovation-friendly environment where scientific results can grow and become products or services that will benefit European economies.


**Keywords:** photocatalyst design; reaction methodology development; mechanistic understanding; flow chemistry; reactor technology; photoreactor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Industrial Manufacturing Process for A high temperature superconducting Coated conductors Technology'.

assistant: **Innovation**

Coated conductors (CCs), known as the second generation of high temperature superconductors (2G-HTS), have triggered broad and fruitful R&D efforts to ensure industrial scalability and enable wide market adoption. Major challenges currently limit the practical use of HTS conductors. First, the high cost / performance ratio imposed by the fabrication methods of kilometre-lengths epitaxial YBCO films that work at too low growth rates limits CC manufacturing throughput. Second, the low throughput in the production of CCs leads to a severe limitation in generating drastic cost reductions for CCs, required for wide market implementation. Due to overall cost, today it remains inefficient to unlock the potential of large-scale applications such as wind turbines, highly efficient and compact industrial scale generators, Superconducting Magnetic Energy Storage and advanced HTS MRI/RMN machines. The overall objective of this Proof of Concept (PoC) proposal is to demonstrate the commercial relevance and to build a business strategy for the industrial scale-up of a new manufacturing process for HTS films, which will push the emerging HTS industry to full market adoption. IMPACT combines low cost (CSD), high throughput (TLA ultrafast growth) and high performance (strained nanocomposites), by integrating additive manufacturing processes and digital printing, to deliver a commercially relevant and industry scalable manufacturing process for HTS CCs. Our value creation process is focused on several inflection points which will pave the way towards commercial implementation of our novel manufacturing process. At the end of IMPACT, we aim to capture value by having identified the commercial exploitation strategies of our technology.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'CHARACTERISATION OF ARKADIA FUNCTION IN THE REGULATION OF SNON STABILITY AND ITS ROLE AS A POTENTIAL TUMOUR SUPPRESSOR'.

assistant: **Concept**

Deregulated signalling by transforming growth factor beta (TGF-beta) plays a critical role in tumorigenesis in humans, acting as a tumour suppressor at early stages, but as a tumour promoter at late stages. To be able to diagnose and treat human cancer, it is essential that we understand these processes at the molecular level. Recent work in the host lab has established that the E3 ubiquitin ligase, Arkadia is an essential component of the branch of the TGF-beta/Smad pathway that is mediated via activated Smad3/Smad4 complexes. The lab has shown that Arkadia functions by targeting the transcriptional repressors, SnoN and Ski for degradation by the proteasome in response to TGF-beta signalling. Loss of Arkadia results in the stabilisation of SnoN and loss of Smad3/Smad4-dependent transcription, two events that are hall marks of some human tumours. Moreover, the host lab has identified an adenocarcinoma cell line, SEG-1, that expresses a non-functional truncated Arkadia protein due to a point mutation. Consequently these cells are deficient in TGF-beta-induced SnoN degradation. Taken together, these results suggest that Arkadia might be a novel tumour suppressor. The first aim of my proposal is to elucidate the mechanism whereby Arkadia mediates TGF-beta-induced SnoN degradation. For this I will take a biochemical and structural approach and will also use siRNA sceening to identify what other components are required. I will also address what genes are regulated by Arkadia by microarray analysis. The second aim is to determine the role of Arkadia in tumorigenesis. I will focus on assessing the effect of restoring Arkadia expression in SEG-1 cells on cell growth and migration in vitro and on tumour growth and metastasis in mouse models. I will also screen for loss of Arkadi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'AgentLink III: A co-ordination network for agent-based computing' in the context of a Sixth Framework call.

assistant: **Objectives**

AgentLink III is proposed as a follow-on to AgentLink II, the IST-funded Network of Excellence for agent-based systems established in August 2000. Agent-based systems are one of the most vibrant and important areas of research and development to have emerged in information technology in the 1990s, and underpin many aspects of the broader IST FP6.Many observers believe that agents represent the most important new paradigm for software development since object-orientation. An agent is a computer system that is capable of flexible autonomous action in dynamic, unpredictable, typically multi-agent domains. Some application domains where agent technologies will play a crucial role include: Ambient Intelligence, the seamless delivery of ubiquitous computing, continuous communications and intelligent user interfaces to consumer and industrial devices; Grid Computing, where multi-agent system approaches will enable efficient use of the resources of high-performance computing infrastructure in science, engineering, medical and commercial applications; Electronic Business, where agent-based approaches are already supporting the automation and semi-automation of information-gathering activities and purchase transactions over the Internet; the Semantic Web, where agents are needed both to provide services, and to make best use of the resources available; Bioinformatics, where intelligent agents may support the coherent exploitation of the data revolution occurring in biology; and others including monitoring and control, resource management, and space, military and manufacturing applications, for example.AgentLink III will act as a unifying focus for agent-based activities in these different domains. As with AgentLink and AgentLink II, the long-term goal of AgentLink III is to put E