RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'EUROPEAN SPACE-GRADE OPTICAL TRANSCEIVERS FOR HIGH SPEED INTRA-SATELLITE INTERCONNECTS AND FREE SPACE LASERCOM LINKS' to be submitted under Horizon Europe.

assistant: **Abstract**

In the current booming satellite ecosystem, optical communications are now the champions of data handling. They are a must for super-capacity transmission systems, and they are a must for smaller and lighter payloads.  The core enabling technology of these systems is the Optical Transceiver. In its most advanced versions, it is deployed either in the form of VCSEL-based or as integrated coherent lightwave modules. These complex products encompass diverse technologies such as lasers, electronic and photonic chips, micro-optics, optical and electrical interfaces, all in sophisticated miniature packaging. European sovereignty in producing such critical devices is of strategic importance, but to this date, a continental supply chain is missing. This is where SPACELINK come to play: SPACELINK is a natural evolution of H2020-SPACE-ORIONAS and SIPHODIAS – two successful EU funded projects, which have demonstrated optical transceiver circuits and modules to TRL >4, establishing the groundwork for the evolution and delivery of flight-ready hardware. SPACELINK is set-up to take the next step and through its manufacturing, assembly, integration and test campaign, will evolve the technology maturity and demonstrate flight-ready parts at TRL 7. SPACELINK aims to establish the first European supply chain of hi-rel optical transceivers, removing dependency barriers and securing Europe’s digital sovereignty.  Leveraging high-end technologies in which Europe has and continues to invest, SPACELINK will deliver optical transceivers made in cost-effective wafer-scale fabrication. SPACELINK will deliver VCSEL-based and photonic integrated circuit systems that will challenge US-made solutions with drastic improvements in Size Weight and Power performance and manufacturability.


**Keywords:*
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'ODYSSEE-MURE, a decision support tool for energy efficiency policy evaluation.' to be submitted under Horizon 2020.

assistant: **Abstract**

The 2012 Energy Efficiency Directive (EED) establishes a set of binding measures to help the EU reach its 20% energy efficiency target by 2020. Countries have also set their own indicative national energy efficiency targets. To reach these targets, EU countries have to implement energy efficiency policies and monitor their impact. The Commission has also the task of monitoring the impacts of the measures to check that the EU is on track with its 2020 target. The objective of the ODYSSEE MURE 2015 proposal is to contribute to this monitoring:•By updating two comprehensive databases covering each EU MS; ODYSSEE on energy consumption and energy efficiency indicators, and MURE on energy efficiency measures;•By providing new and innovative trainings and didactical documents to national, regional and local administrations in EU MS to raise their capacity and expertise in the field of energy efficiency monitoring and impact evaluation.•By extending the evaluation of the impact of energy efficiency from energy and CO2 savings, as already done in ODYSSEE, to the multiple other benefits.The updating of two databases ODYSSEE and MURE will play a key role to provide updated and centralized information required by each MS and the Commission to assess, monitor and evaluate energy efficiency progress and the state of implementation of measures and their impact.The project will provide innovative training tools and documents in a very user friendly way to public administrations to help them in implementing the monitoring of the progress achieved with indicators, in designing new policy measures and assessing the impacts of these measures, not only in terms of energy savings, but also in terms of the other benefits linked to energy efficiency improvements.Finally, the project will try t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Range-adapting reinforcement learning and memory' (RaReMem), addressing dissemination and exploitation.

assistant: **Impact**

A wealth of evidence in perceptual and economic decision-making research suggests that the subjective value of one option is determined by the range of the values of other available options (i.e., the context). Yet, up until today, this literature has almost exclusively focused on decision situations where contexts are explicit and static, thus ignoring more ecological and realistic scenarios where value ranges are dynamically shaped by past outcomes. This proposal will investigate if and how range adaptation also affects the computation of outcome values that are acquired from experience and stored in memory. We hypothesize that range-adaptation is pervasive in learning, because it addresses a fundamental computational cost-benefit trade-off.Indeed, we propose that, although range adaptation is locally optimal, because it optimizes information processing by tuning the value response function to the experienced outcome distribution, this comes at the price of forfeiting the capacity to generalize learned-values to new contexts. The proposed research will design and validate a comprehensive behavioural and computational framework to test this hypothesis. More precisely, combining original experimental paradigms, behavioural analyses and computational modelling, we will i) provide a clear algorithmic description of outcome range adaptation, ii) elucidate the nature of the distorted memory representations of outcome values, and, finally, iii) probe the pervasiveness and adaptive value of this process empirically (by running experiments in different cultures) and theoretically (through extensive simulations). We believe this project has the potential to further elucidate new fundamental computational constraints of human learning and decision-making. Our theoretical framewo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'IARC International Fellowships Programme' (2007-2013).

assistant: **Innovation**

The mission of the International Agency for Research on Cancer (IARC) is to promote international collaboration in cancer research for cancer prevention and control. One of the statutory functions of IARC is the training and education.  The Agency seeks to achieve this aim through IARC’s International Fellowship Programme and its International Courses Programme which are designed to assist the development of cancer research and prevention in all countries, with special emphasis on low- and medium-income countries (LMICs) in which such work is not well established, and to train future collaborators in the scientific programme of the Agency.The aim of IARC’s Postdoctoral Fellowships is to provide young scientists from any country with training in a research Group at the Agency in aspects of cancer research ranging from biostatistics and epidemiology (including genetic and molecular) to mechanisms of carcinogenesis, with an emphasis on interdisciplinary projects. The choice of the host group is made by the Fellows.IARC is particularly committed to promoting the development of expertise in cancer research in LMICs countries by training researchers from these countries who can return to their own country to implement and develop programmes in cancer research or cancer control.IARC offers a supportive research environment, in which individuals are valued, encouraged and supported. Ample opportunities of formal and informal training are offered in scientific or complementary matters, either on the job or in dedicated training sessions. IARC has recently implemented a Fellowship Charter with the aims of providing more structured career development for Fellows and of improving their training experience.The support of COFUND would allow IARC to continue to improve its training ac
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Biofuels through Electrochemical transformation of intermediate BIO-liquids' (EBIO), addressing dissemination and exploitation.

assistant: **Impact**

The availability of compact and cost-efficient solutions for sustainable energy production is essential for renewables to become Europe's dominant primary energy source. EBIO will contribute to achieve EU’s ambitious objectives, by providing an innovative technical solution for the sustainable and socially acceptable conversion of low value crude bio liquids, specifically fast pyrolysis oil and black liquor, into energy dense transport fuels. The core of EBIO is the electrochemical upgrading of liquefied biomass to stable and energy dense bio oils and further refinery co-processing to premium transport fuels. The former step consists of successive depolymerisation, hydrogenation and decarboxylation, optimised by developing electrode materials, cell designs, separation processes and efficient integration into existing biorefinery infrastructure. An efficient, compact and safe process will be developed, operating at mild conditions, and targeting a carbon yield from crude bio liquid to transport fuel above 60%. The experimental development is supported by a broad sustainability analysis including economic feasibility, environmental footprint and impact on society and rural development.EBIO will validate the new technology at lab-scale (TRL4), using an integrated approach covering the entire process, using variable feedstock, minimising separation costs, and increasing resource and carbon efficiency. The lab scale process developed will be the prototype for a future fuel production system serving as buffer for fluctuating electricity availability. Wide implementation of EBIO technology will lead to a decrease of at least 190 MtCO2 / year, and the production of at least 61 Mt biofuels/year, considering only pyrolysis oils and black liquor feedstock.The EBIO consortium provi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Towards the Engineering of High-Capacity Viral Vectors for Neuromuscular Diseases' (TEHC), addressing dissemination and exploitation.

assistant: **Impact**

Gene therapies are a fast becoming a realistic treatment for patients suffering from genetic disorders. To date, systemically applied invivo gene therapies exclusively rely on adeno-associated viral (AAV) vectors for gene delivery to affected cells. AAV vectors have manyfeatures that make them successful gene delivery tools and through biomining and bioengineering efforts over the years, AAVvariants are able to transduce a number of clinically relevant targets. However, many cell types, including human muscle cells, are notsufficiently transduced by existing viral vectors. Another challenge is the small genome size of AAV vectors, which is frequently aproblem for neuromuscular disorders where affected genes are larger than in other types of disorders. In the light of these challenges,we are proposing to tackle new avenues for viral vector engineering in two separate, but related, objectives. Objective one is a newway of viral vector re-targeting through incorporation of single domain antibodies (nanobodies) followed by a directed evolutionaffinity maturation step. This approach of adds value to an already published method and should create a capsid-nanobody fusionthat is fit for purpose and potentially also has benefits regarding the evasion of pre-existing antibodies and improved packaging. Thesecond and more ambitious objective of our proposal consists of the adoption of a novel bacteriophage-based viral vector capable oftransducing mammalian cells and delivering up to 171 kilo base pairs of DNA. We are proposing to couple this new vector systemwith our experience in capsid bioengineering and gene therapy, which has not been done before. For this objective, we propose toincorporate antibody-derived targeting molecules such as nanobodies and single-chain variable fragm
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Mismatch recognition by dna repair enzymes'.

assistant: **Concept**

Research objectives and content The overall aim of this project is to gain a thorough understanding of the molecular details of mismatch recognition by DNA repair enzymes. To do this, the interactions between E.coli MutS and synthetic DNA duplexes containing various mismatches and mutagenic bases will be estudied.The properties of the complete (96KDa) protein will be studied by a variety of biochemical techniques. In addition the structural details of MutS binding by preparing truncated derivatives (<30Kd) which retain mismatch binding activity will be examined. For this research programme, MutS protein and some regions of it will be synthesized and some techniques will be used to study the Interaction with mismatches in DNA: Footprinting, filter binding and gel retardation studies Ultraviolet melting (thermodynamic studies) Protein sequencing to determine the primary amino-acid sequence of MutS that binds to mismatches Crystallization of MutS and mini-proteins and their complexes with mismatches DNA Training content (objective, benefit and expected impact) This project will be a benefit for learning some of the techniques currently used in biochemistry assays. Having a better understanding of the features concerning the mismatches in DNA, could led to a closer knowledge of the causes and the therapy of cancer. Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Road-mapping E-Government RTD 2020' (EGOVRTD2020).

assistant: **Innovation**

The eGovernment roadmap project aims at identifying and characterizing the key research challenges, required constituency, and the implementation model for a comprehensive European initiatives on holistic and dynamic government 2020.The vision is to transform the European Government landscape into a coherent community anticipating customer needs and leveraging the potential of the diversity and innovativeness of public agencies, and transforming the Union to the world leading knowledge society. The project will develop visionary scenarios for eGovernment research 2020 and a detailed roadmap for the transformation process. This will include measures for research, development, demonstration, implantation, dissemination, promotion, and assessment, trading and standardization.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Simulation, Diagnosis and Detection of the Anthropogenic Climate age' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

To develop and to improve global coupled ocean atmosphere climate models, to simulate the anthropogenic climate change using these models, and to diagnose the effect of the anthropogenic climate change as simulated by the models and to assess the uncertainties. The present and future climate will be simulated with a hierarchy of global coupled ocean-atmosphere climate  models, which are developed at the different institutes participating in the project.  The use of different models and simulations carried out at the different institutes is essential in order to identify  the model dependency of the results, and also because the simulations are so costly that each institution can only  perform a limited number. Many experiments are needed to assess the variability and significance of the  simulations.  With these model experiments it will be investigated, how large the natural variability of the climate is and to  what extent mankind has already influenced the present day climate. It will be studied how the anthropogenic  emissions of greenhouse gases and aerosols will influence the future climate. This analysis will not only be  confined to primary quantities (like near-surface temperature change, sea level rise), but also to important  climate parameters, such as storm-frequency, hurricance frequency, daily temperature range, length and  frequency of droughts.  Furthermore, advanced statistical techniques will be employed to estimate, what degree of confidence can be  assigned to the model simulations, and to what extent observed climate variations can be tributed to  anthropogenic emissions or to natural fluctuations of the climate system (fingerprint analysis).  The project will give information about the future climate change and the reliability of this prediction.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Towards Early diagnosis and biomarker validation in Arthritis Management' (EURO-TEAM) under Seventh Framework.

assistant: **Objectives**

An ideal intervention in a chronic inflammatory disease such as Rheumatoid Arthritis (RA) would be a preventive one. In order to develop preventive strategies and therapies two key developments need to occur: (1) Biomarkers need to be identified that can be used to predict an individual’s risk of developing RA. (2) Modifiable disease mechanisms need to be identified and characterized in the early phases of disease. The key objective of the TEAM consortium is to specifically identify diagnostic biomarkers and disease mechanisms operating during the transition from health to rheumatoid arthritis. Our consortium will achieve this by developing a collaborative, integrated programme of work that links researchers with key SMEs involved in biomarker development to produce a “personalized predictive bioprofile” for patients destined to develop RA. The Euro-TEAM consortium will deliver a step change in the development of biomarkers and diagnostic kits that are timely, strategically important for European SMEs, and based on a disease (RA) in which concrete genetic and environmental risk factors have already been established. Firstly, it will directly compare biomarkers in the preclinical phases of disease with established markers in the clinical phases. Secondly, it will look beyond the synovium interrogating lymphoid, lung and periodontal tissue in a first-in-class approach to measuring systemic changes in the earliest phases of disease. Thirdly, it will place great emphasis on understanding why synovial inflammation resolves in some individuals and develop biomarkers of this “reverse” phase. Fourthly, it will explore a key cell type (stromal cells) that has been almost completely ignored in current biomarker studies. Finally, it will directly involve patients and other special
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Soft Chemical Control of the Physical Properties of Layered Solids' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

This research programme is fundamental solid state chemistry at the boundary with condensed matter physics. It will discover new transition metal compounds with layered crystal structures and aims to put them on the world stage by exploiting the compositional tunability which is intrinsic to non-molecular systems. The discovery and chemical rationalisation of new composition-structure-property relationships is anticipated to lead eventually to future industrial developments in applications as wide ranging as superconductors, thermoelectric materials, magnetic materials, batteries and heterogeneous catalysis. Parallel to the research, the fellow’s outreach activities will centre on highlighting these “synthetic minerals” to the general public in a permanent exhibit. The host group and the fellow bring complementary expertise to the project and the career development of the fellow will be through the research and outreach and also in the development of collaborations with Oxford Physics, and the world-leading international facilities for neutron and synchrotron X-ray science at the local Harwell campus and in Grenoble.The project will develop science and the fellow through the pursuit of ground-breaking and adventurous research directions at one of the forefronts of solid state chemistry. It will be carried out in an internationally leading group in a chemistry department in the top handful in Europe.