RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Solid State Quantum Technology and Metrology Using Spins' to be submitted under Seventh Framework.

assistant: **Abstract**

The development of quantum devices by nanoscopic control of constituents is expected to be one of the largest and most intriguing challenges of modern solid state physics. Among the degrees of freedom which allow exploiting most quantum phenomena are spins. Their long coherence and relaxation times make them of interest to any kind of quantum spin”tronics” from spin memories to quantum computing and ultrasensitive sensors. In well chosen and engineered environments spin state control and readout can be easy and robust even under ambient conditions. It is the aim of the present proposal to develop complex single spin systems from diamond defects and other dopant/host systems to a degree known hitherto only in atomic physics in terms of controllability and isolation from their environment. These systems should be used to investigate fundamental physical properties, e.g. the quantumness of solid state spins as well as their utilization in sensory devices.To this end spin defects should be implanted into ultrapure diamond materials with a spatial precision below 10nm. Their relaxation properties should be optimized to the ultimate (spin phonon interaction) limit and individual spin quantum states should be read out in a quantum non demolition-type measurement with highest possible fidelities. This on the one hand will allow the set up of versatile quantum arrays to e.g. study quantum many body physics. On the other hand such structures will yield sensors for magnetic and electric fields with unprecedented sensitivity and scale spatial resolution. Such devices might have revolutionary impact on imaging applications in various fields from materials’ investigation to bio sciences.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Continuous hazardous water Pollutants sensing in the environment' (CoPs) under Horizon 2020.

assistant: **Objectives**

CoPs combines the expertise of the 3 industry partners – ground-breaking electrochemical sensors developed by IPM, miniaturised electronics customised by PAL and CAU’s geo-monitoring hardware and software – and is expected to bring economic, social and environmental impacts, including towards achieving UN SDGs and EU policy.Pesticide and nitrate pollution in fresh waters pose a significant risk to public health and the environment. Exposure to pesticides can lead to several cancer types or Parkinson’s disease, while nitrate can result in “Blue Baby Syndrome” and cause eutrophication. According to latest estimates, getting sick from drinking tap water in Europe had a societal cost of €220 million. Meanwhile, inefficient water monitoring based on sampling and lab analyses does not provide early alerts. Water suppliers need to meet EU monitoring requirements and react instantly with contamination treatment protocols, protect water supplies and avoid economic losses through shutdowns.Our innovative solution rapidly detects specific water pollutants and transmit real-time data on contaminant levels and movements in natural water systems before they could reach water infrastructures and consumers. It saves both time and costs (by at least 40%), it vastly improves data quality and quantity, and it provides a data analysis and hazardous pollutants alert service to monitoring agencies.Our goal is to mature, scale-up and demonstrate the production of the CoPs sensor platform for continuous in-situ water monitoring, targeting water suppliers as initial clients, and with the potential to create new markets within the agriculture and private well owner segments.A successful CoPs project will allow us to create measurable impacts on our companies, quantified as accumulated revenue of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Solar powered atmospheric plasma system for the treatment of contaminated wastewater' to be submitted under Horizon Europe.

assistant: **Abstract**

Atmospheric plasma (AP) is envisioned as a revolutionary green technology for wastewater treatment as compared to conventional biological and advanced oxidation processes due to its robust performance in degrading recalcitrant emerging contaminants and micropollutants. AP powered by DC, AC, or pulsed power sources, in the air or in contact with water produces a multitude of reactive species able to attack and ultimately mineralize the contaminants dissolved in water. Salient features of this novel technology include operation at NTP, flexibility, rapid startup, in situ generation of reactive species (e.g. H2O2, O3, ˙OH, ˙NO, NO2˙) without chemical addition which makes it a futuristic green technology. However, an inherent disadvantage is its high energy cost which hinders its large scale application; only a few examples of treatment of real water samples are indeed reported. Previous research on AP application for emerging contaminant removal also lacks in designing and selecting a plasma discharge capable of treating surfactant and non-surfactant types of emerging contaminants efficiently. Therefore the objectives of this proposal include the development and testing of a standalone solar-powered dual discharge plasma reactor (SolarPlas) for sustainable wastewater treatment targeting efficient removal of emerging contaminants of surfactant and non-surfactant nature. The dual discharge will consist of 1) plasma in contact with liquid at the gas-liquid interface for destroying surfactant type of emerging contaminants while 2) plasma discharge at the bottom of the reactor diffused through the air bubbling will effectively degrade non-surfactant type of emerging contaminants from Hospital wastewater and landfill leachate. The main outcome of the project will be in the form
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Energy efficient Mortgages Action Plan' (EeMAP), addressing dissemination and exploitation.

assistant: **Impact**

In the EU, buildings are responsible for 40% of total energy consumption and 36% of CO2 emissions. By improving the energy efficiency (EE) of buildings, the EU’s total energy consumption could be reduced by 5-6% and CO2 emissions by 5%. Considering that the building stock constitutes the largest single energy consumer in the EU, and that the value of the European mortgage market is equal to 53% of EU’s GDP, there is huge potential to bridge financial innovation and the EE world and to unlock the benefits of mortgage financing to support EE to the benefit of all.The EeMAP Project intends to deliver a standardised framework based on a market benchmark to stimulate EE investment by households in the EU’s housing stock by way of a private banking financing mechanism.Three key outputs will be: a framework for a building energy passport, recording the EE history of a property by recognising the improvements made; a framework that can integrate the “green value” of a property through EE and collected market data; the framework for an EE mortgage product. Accordingly, EE investment will become financially viable, as market transparency will be improved. The Project will create synergies in the mortgage and covered bond value chain, delivering a virtuous circle between lenders, borrowers and investors from the origination of the energy efficient mortgage to the pooling of EE collateral for the purpose of energy efficient covered bonds. EeMAP has long-term potential to drive housing markets across Europe in a sustainable manner and encourage significant energy reductions in line with the EU’s aspirations and global climate change demands. Concretely, issuing 35,000 green mortgages a year can achieve savings of 88 GWh per annum.The EeMAP Project brings together all the necessary c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Hypoxic Tumour Models for Photoactivatable Ruthenium-based Chemotherapy'.

assistant: **Innovation**

In this Proof-of-Concept project I will show the commercial potential of ruthenium-based photoactivated chemotherapy (PACT) compounds developed in my ERC Starting Grant by demonstrating their efficacy on hypoxic cancer models. Photoactivated chemotherapy  is a new class of phototherapy to treat cancer. In principle, PACT looks similar to photodynamic therapy (PDT): light irradiation of the tumour in vivo leads to local activation of the anticancer prodrug, thereby limiting the toxicity of the treatment to the diseased tissue, and thus lowering side effects for the patient. However, the mechanisms of PACT and PDT are very different: in PDT the light-absorbing prodrug requires molecular oxygen to kill the cancer cells, whereas in PACT oxygen is not involved in prodrug activation. As a consequence, PACT agents should be able to treat hypoxic tumours, which are characterized by low oxygen concentrations and high resistance to PDT and other existing therapies. In this project the efficacy of a selection of  Ru-based PACT compounds will be tested in hypoxic cancer models and compared to their efficacy in normoxic conditions. In parallel I will develop, in collaboration with my network of collaborators from the clinics, business analysts, and patent attorney, a plan for (pre) clinical development of PACT compounds.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Noc ima svojo moc (The Night has its Might), Euripean Researchers' Night (NIGHT)' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Firmly supported by local, regional and national media, the awareness campaign Waters' Might introduces the project ""Noc ima svojo moc"" (NOCMOC) to Slovenian and other EU citizens.The core objectives of the NOCMOC project is to raise awareness about the research and its benefits, overcome stereotypes, stimulate curiosity and excite youngsters to take up the research careers.Efficient communication tools, successfully used in previous project editions, TV and radio broadcasts, press-releases in printed and social media tend to reach over 700.000 people. Generated by past experiences, the awareness campaign will explore Waters and include 1.200 groups, families and individuals to participate in Citizens Science project. Citizens' contribution to the research methodology practice will be implemented by the use  ""hands-on""  and/or other research tools in a basic and user-friendly way.Previous NOCMOC editions have developed a strong and sustainable growing network of interested partnering institutions in more than 25 cities in Slovenia, attracting even other EU cities in a year of Slovenian presidency of the European Union Council.The project will bring together over 40 research-related institutions to raise awareness about research and innovation, its relevance to implement the Green Dealgoals, its social and economic benefits, and its variety of careers.We aim for 35.000 visitors from different target groups to participate in the NOCMOC activities spread all over Slovenia. Over 200 activities: science festivals on the main squares of four Slovenian cities, science shows, simulations, research and technical days in primary and secondary schools, lectures and workshops in public spaces (libraries, retirement homes, museums), science espressos, STEAM events, EU corners, o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Novel nanometrically structured therapeutic hydrogel as injectable for fascial tissues surrounding the nerves intended for preventive treatment of chronic pain' (TherGelFas) targeting Horizon 2020.

assistant: **Abstract**

The key goals of the “TherGeLFas” project are: (a) the training of a talented experienced researcher in the fast growing field of innovative biomaterials for medical applications where the host and partner institutions have a critical knowledge and expertise; and, (b) the design and development of cost- efficient polymer materials in order to develop a new medicinal product for post-operative acute pain treatment and prevention of chronification.The aim of the research project and the main scientific challenge is thereby to develop a ‘therapeutically effective’ hydrogel based injectable product to be applied during and post-surgery in the fascial tissue that protects the nerves where the pain originates and chronifies. TherGelFas expects to create the proof of concept of a new medicinal product by combining advanced materials (a biodegradable, antiseptic and biocompatible carrier, made of porous nanostructured hydrogel based on hyaluronic acid) with the ability to load and release non-steroidal antiinflamatory drugs in a controlled manner. It is aimed for the improvement of the current multimodal strategies of peripheral nerve blockade injections used during and post-surgery in acute pain treatment to prevent it from becoming chronic and that unfortunately are unsuccessful many times. The first achievement will be that of the training of the experienced researcher in new areas of knowledge such as business development from original concept stages to production scale-up, manufacturing and marketing stages. The second achievement will be to scientifically assess whether these hydrogels can improve and replace currently used therapies, to develop a proof-of-concept scalable product. The third achievement will be to learn how to perform correctly the necessary steps needed
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Deciphering the molecular mechanisms of skeletal muscle fiber fusion' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Skeletal muscle fibers are highly organized multinucleated cells that grow and regenerate by fusing with myocytes derived from their resident stem cells. The fusion between myocytes and mature muscle fibers, which underpins the remarkable adaptability of muscles, is molecularly distinct from the fusion events that occur during development. This secondary fusion process, also known as myonuclear accretion, integrates mononucleated myocytes into immature myotubes or mature fibers, supporting muscle growth, repair, and regeneration throughout life. Despite its critical physiological importance, the mechanisms governing secondary fusion and the active role of myofibers in this process remain poorly understood.Leveraging the development and application of high-content screening, advanced biochemistry, genetics, cell biology, transcriptomics, and cutting-edge imaging techniques, including 3D correlative light and electron microscopy (CLEM), we aim to provide groundbreaking insights into the molecular and cellular processes of secondary fusion. To achieve this, we will address three independent but interconnected aims:Aim 1: Screen for regulators of secondary fusion and determine their effects using high-content imaging together with exploratory molecular studies.Aim 2: Elucidate the molecular mechanisms and cellular dynamics underpinning fusion hotspots.Aim 3: Establish the physiological relevance of myonuclear accretion in vivo by visualizing fusion hotspots and evaluating the impact of enhanced myoblast transplantation on muscle regeneration and function.This synergistic approach will transform our understanding of muscle physiology, bridging the molecular mechanisms with their functional outcomes. The findings promise to uncover new principles of cell fusion, organelle dyn
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Advanced Turbulence Simulation for Aerodynamic Application Challenges', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The ATAAC project aims at improvements to Computational Fluid Dynamics (CFD) methods for aerodynamic flows used in today’s aeronautical industry. The accuracy of these is limited by insufficient capabilities of the turbulence modelling / simulation approaches available, especially at the high Reynolds numbers typical of real-life flows. As LES will not be affordable for such flows in the next 4 decades, ATAAC focuses on approaches below the LES level, namely Differential Reynolds Stress Models (DRSM), advanced Unsteady RANS models (URANS), including Scale-Adaptive Simulation (SAS), Wall-Modelled LES, and different hybrid RANS-LES coupling schemes, including the latest versions of DES and Embedded LES. The resources of the project will be concentrated exclusively on flows for which the current models fail to provide sufficient accuracy, e.g. in stalled flows, high lift applications, swirling flows (delta wings, trailing vortices), buffet etc. The assessment and improvement process will follow thoroughly conceived roadmaps linking practical goals with corresponding industrial application challenges and with modelling/simulation issues through “stepping stones” represented by appropriate generic test cases.The final goals of ATAAC are:•  to recommend one or at most two “best” DRSM for conventional RANS and URANS;•  to provide a small set of hybrid RANS-LES and SAS methods that can be used as “reference” turbulence-resolving approaches in future CFD design tools;•  to formulate clear indications of areas of applicability and uncertainty of the proposed approaches for aerodynamic applications in industrial CFD.Contributing to reliable industrial CFD tools, ATAAC will have a direct impact on the predictive capabilities in design and optimisation, and directly contribute to th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Development of a combined Influenza/SARS vaccine' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

We propose to develop the replication defective influenza delNS1 virus as a vector for antigens derived from the SARS-associated corona virus (SARS-CoV) to a stage for use in clinical phase I trials. The resulting virus (Flu/SARS) will have the potential to induce immunity against both, influenza virus and SARS-CoV. First we will define relevant SARS-specific antigens. This will be achieved by the software suite, EpiScore and subsequent immunogenicity studies with peptides. The most promising antigens that evolve from this process will be introduced into the delNS1 virus vector. In parallel we will construct a delNS1 vector which can be used to effectively express foreign antigens. This will be achieved by expressing a model antigen in different sites of the delNS1 virus. The construct which shows the best balance between immunogenicity and level of attenuation will be used for expression of the defined SARS-antigens. The ability of the resulting construct (Flu/SARS) to induce neutralizing antisera, CTLs that destroy virus infected cells, to confer protection against viral challenge as well as their level of attenuation will be analysed in mice and in ferrets. The construct which shows the best profile according to these criteria will be produced, purified and filled under GMP-conditions. With the resulting vaccine lots, toxicology studies will be performed. The consortium of this proposal comprises the companies emergence which is renowned for its know how in defining epitopes, Green Hills Biotechnology which is highly experienced with in-vitro mutagenesis of influenza viruses, Bio test which has established mouse and ferret animal models for viral infections, Biaseparations which has developed a superior method for purification of live viruses, and the Goethe Universi