RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Common access to immunogenetics data: the integrated immunogenetics database' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

The ImMunoGeneTics database, IMGT, is an integrated specialised database containing nucleotide sequence information of genes important in the function of the immune system. It collects and annotates sequences belonging to the immunoglobulin superfamily which are involved in immune recognition, these are the Immunoglobulins (Ig), the T cell antigen receptors (TcR) (LIGM-DB) and the Major Histocompatibility Complex (MHC). In humans, the latter are referred to as the Human Leucocyte Antigens (HLA) system (HLA-DB). Collection and analysis of such sequences is important for the understanding of disorders of the immune system such as infectious diseases, autoimmunity, allergy or tumour development, and for the development of antibody engineering, transplantation and immunotherapy. IMGT works in close collaboration with the EMBL database and uses sequence information from the EMBL database for expert annotation. As the EMBL database is a generalist database, it collects sequences of all types from all species, there are insufficient resources for specialised information to be added. In IMGT however such information is added in a consistent and standardised way by expert annotators. This annotation procedure includes verification of the sequence data by homology studies using multiple sequence alignment tools, and also labelling of the sequence, which cannot be carried out at the generalist databanks. By updating the information held at the generalist databases from the specialist databases, the quality of the information will improve. This project requests support for the European partners involved in the expansion phase of the IMGT database. LIGM (France): project coordinator, responsible for the IMGT database design and structure, software development for sequence annotation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Monetising performance culture in French North and West Africa (MPA)' (MPA).

assistant: **Innovation**

Monetising performance culture in French North and West Africa (MPA) investigates how the implementation of authors’ rights systems affected the production of African performance culture in the period from 1850 to 1960. MPA bridges the field of French colonial history and intellectual property history by analysing the establishment of performing rights societiey offices in North and West Africa and the consequences that these had for local artists and creative production. The goal of the research is dual: first, I aim to develop a historical theory of the legal acknowledgement and monetisation of music, drama, and other performance practises in North and West Africa. Secondly, I aim to provide an account of historical alternatives to the organisation of creativity that did not fit into the rights-oriented performance culture that developed in Europe. MPA is a historical analysis of archival sources that will be collected and cross-referenced from a number of institutions in France, Senegal, and Benin. One major outcome will be an open digital map outlining when and where performance rights society offices opened and closed in the region between 1850 and 1960. This will be done in collaboration with supervisor and host, Ashleigh Harris, who is the PI for the African Literary Metadata (ALMEDA) project at Uppsala University. Other outcomes will be the publication of two peer-reviewed articles, one on local resistance to authors' rights systems, the other on IP-literacy among African artists. To be able to undertake the archival analysis and to expand the research into African cultural history, the outgoing phase will be carried out at the Université d’Abomey-Calavi in Benin where Didier Houénoudé will supervise and host me. In addition, I plan a three-month secondment at t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Empowering Africa's Point of Care with Cutting-edge Graphene Biosensing for Rapid Detection and Interconnected Surveillance of Novel Ebola Virus Outbreaks.', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

This project proposes developing, preclinical and clinical validation of a Point of Care (PoC) biosensing platform based on multiplexed field-effect sensor technology based on graphene monolayers functionalized with specific and oriented recognizing biomolecules (BioGFET). This technology will be used for the rapid and remote diagnosis of Ebola infection by titrating specific biomarkers in peripheral blood samples. To strengthen the diagnostic ability and offer a robust differential triage of patients, serological biomarkers specific for the virus and biomarkers specific for infection severity will be analyzed and compared simultaneously (Figure). Therefore, the final correlation between the achieved parameters will offer a robust and rapid triage of patients, thus, permitting to identify rapidly at the point-of-care potential Ebola outbreaks and offering to physicians a more precise overview of the patient status before knowing the confirming laboratory results. Besides the proposed technology, another key point of this device is represented by its IA-based cloud networking. In fact, once processed and retrieved, the locally achieved diagnostic results will be transmitted to a central server (for example, located in a General Hospital), processed by a custom-made IA software, and, in case of necessity, a health warning will be sent to all the interconnected platforms, independently to their location.


**Keywords:** Diagnostics, Graphene, Biosensors, Sentinel AI, Internet of Things
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Table-top x-ray lasers pumped by fas laser pulses', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The main task of the project is the experimental investigation of possibilities for X-ray lasing in the ultrashort time range. The key tool for this project is the MPQ-femtosecond-terawatt-laser (one out of only a few comparable laser systems in the world) which gives the opportunity of creating high density laser plasmas in extremely short times. Therefore a totally new physical plasma regime is accessible which may allow the creation of trasient X-ray lasing as well as the adaptation of mechanisms successfully used for longer time scales. All the efforts in the field are aimed at creating a 'table-top X-ray laser' in the so-called 'water windows' wavelength range (23A to 44A). and these pIanned investigations are meant to be a wide step in this direction. The second part of the project is the experimental demonstration of possible applications of X-ray lasers, eg. for X-ray holography, nonlinear optics and plasma diagnostics.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Moonlight-dependent Hormones Orchestrating Lunar Reproductive Periodicity and Regeneration' in the context of a Seventh Framework call.

assistant: **Objectives**

The moon governs reproductive cycles in a broad range of marine animals, including cnidarians, polychaetes, crustaceans, echinoderms and fishes. Even outside the animals, lunar reproductive cycles have been described, such as in brown algae or foraminifers. Despite their fundamental nature, and decades of classical observations, close to nothing is known about the molecular processes that underly these lunar reproductive cycles.We will take advantage of the recent advance in molecular resources and tools in the bristle worm Platynereis dumerilii, which has long served as a key model for classical experimental studies on lunar periodicity. The combination of modern techniques with well-founded classical observations will allow us to decipher, for the first time, the hormonal cues that are regulated by the lunar cycle and are responsible for the orchestration of gonadal maturation and trunk regeneration.The project builds on established methodology, as well as on the first results of a successful pioneer screen and has three major aims:(1) the functional investigation of two hormones we recently identified to be under lunar cycle control.(2) the extension of our successful pioneer screen to understand to which extent other neurohormonal components change over the lunar phase.(3) the identification of the elusive inhibitory brain hormone that directly acts on the gonads to inhibit premature maturation.Together, these experiments will lead us to first significant insights into the molecular nature of the hormonal network that underlies moonlight-dependent periodicity and regeneration.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'TextrodeMisc – TEXtile elecTRODE Matrix for Improved Surface eleCtromyography signal quality and usability in applications for people with limb loss' (TextrodeMisc).

assistant: **Innovation**

Textile-based electrodes are about to be competitive alternatives to traditional electrodes for ECG and EMG. Electrodes integrated into textiles are easier to use which facilitates home-based monitoring, treatment and rehabilitation measures. One potential key application is Phantom Limb Pain (PLP) treatment using Phantom Motor Execution (PME), where EMG signal from the remaining muscles of the amputated limb is used to control a Virtual Reality (VR) representation of the lost limb. However, textile electrodes still need to be improved regarding electrode contact and adhesion to the skin. This calls for new sensing materials that may not have textile properties and thus need to be integrated into the textile in new ways. So, the aim of this project is to a) try new sensing materials that will improve the electrode contact and adhesion to the skin, and b) find ways to solve the interfacial linkage between the sensing material and the textile substrate. The project will focus on novel materials and textile construction development to overcome these issues. The main project deliverable is generic textile matrixes of electrodes that can be competitive alternatives to traditional electrodes. This should contribute to making e.g. PLP treatment generally available and easy to use as improved electrode signal quality would lead to better treatment effect, durability and sustainability. The concept of controlling the lost limb (central to the PLP treatment based on PME) is directly transferable to myoelectric controlled prostheses. Thus, we also aim to test what the new type of electrode matrixes could contribute to this “twin” application. The applicant's expert knowledge in sensing materials can together with smart textile experts (University of Borås), biomechatronic and pain
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Questions of decidability and definability in the Enumeration degrees'.

assistant: **Concept**

We propose to ascertain if there is an effective procedure that determines the validity of an arbitrary first order $\forall\exists$-sentence in the upper semi-lattice of the $\Sigma^0_2$ enumeration degrees. It is known that the $\forall$-fragment of the first order theory of the $\Sigma^0_2$ enumeration degrees is decidable. Slaman and Woodin (1996) proved that first order theory of the $\Sigma^0_2$ enumeration degrees is un-decidable and more recently, Kent (unpublished) proved that the $\forall\exists\forall$-fragment of this theory is un-decidable.This left open the question of whether the $\forall\exists$-fragment is decidable. Answering this question is equivalent to finding an effective procedure that determines, when we are given an arbitrary finite lattice $P$ and finite lattices $Q_0$, ..., $Q_n$ which extend $P$, if there is an embedding of $P$ into the $\Sigma^0_2$ enumeration degrees which cannot be extended to an embedding of any of the $Q_i$. Lempp, Slaman and Sorbi (to appear) have shown that the sub-problem where $n = 0$ is decidable.In order to fully answer the question, we propose to answer the above problem in the following three sub-cases:Case 1: Let $P$ be an arbitrary finite anti-chain and each $Q_i$ a one point extension of $P$.Case 2: Let $P$ be an arbitrary finite lattice and each $Q_i$ a one point extension of $P$.Case 3: Let $P$ be an arbitrary finite anti-chain and each $Q_i$ an arbitrary extension of $P$.To answer the first case, more research needs to be performed on the properties of Ahmad pairs. In particular, we propose to determine the maximal size of an anti-chain where each two distinct elements form an Ahmad pair. Also, we propose to determine if the join of an Ahmad pair is non-trivially bounded from above. Cases 2 and 3 are exten
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Bacteria-mucin interactions – Shaping intestinal epithelial responses in health and disease' (Bac2MUC).

assistant: **Innovation**

The intestinal microbiota consists of beneficial commensal bacteria and pathobionts that cause inflammation. The intestinal mucus layer dictates how specific members of the microbiota affect health and disease. The mucus layer consists of soluble mucins and epithelial transmembrane (TM) mucins that regulate host responses. The molecular mechanisms as to how the intestinal microbiota affect the functions of TM mucins is largely unknown. My recent work shows that TM mucin MUC1 is a key receptor for Salmonella invasion into polarized epithelial cells. We also discovered that MUC13 is a central regulator of epithelial barrier formation. I hypothesize that bacteria-mucin interactions shape epithelial responses by stimulating healthy barrier formation, driving inflammation or mediating bacterial invasion. My aim is to unravel molecular mechanisms via which distinct bacterial species regulate the functions of TM mucins MUC1 and MUC13 in the intestine.   The key objectives of Bac2MUC are to: 1. Identify commensal and pathogenic bacteria that target TM mucins 2. Elucidate TM mucin signaling pathways activated by commensal and pathogenic bacteria 3. Determine the function of TM mucins during inflammation and invasion 4. Utilize bacteria-TM mucin interactions to unravel healthy epithelial barrier regulation  I will use an innovative large-scale screening platform to identify novel bacteria-mucin interactions. TM mucin signaling pathways during bacterial interaction will be characterized by sortase technology. Cutting-edge technologies such as CRISPR/Cas9 genome editing and advanced microscopy will be applied in established bacterial infection assays with intestinal cell lines and organoids.  Bac2MUC is an ambitious and ground-breaking project that will address, for the first time,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Startup Europe Partnership' in the context of a Horizon 2020 call.

assistant: **Objectives**

Established by the European Commission in January 2014, the Startup Europe Partnership (SEP) is the first pan-European open platform dedicated to supporting the growth and sustainability of European startups able to compete and raise funds at international and global level. SEP is thereby the first Startup Europe Initiative focused on scaling up new innovative ventures, by scouting the most promising European startups and connecting them with the large and medium corporations. The latter are committing capital, seniority (involvement of heads of innovation office or corporate development) and procurement channels to support startups in different ways.SEP was developed in partnership with key actors in the EU startup ecosystem, including leading corporates (Telefónica, BBVA, Orange), educational institutions (Cambridge University, IE Business School, Alexander von Humboldt Institute for Internet and Society), and investors (AngelList and the European Investment Bank Group/European Investment Fund). To reach the goal of helping the best European startups to scale-up, SEP will initially revolve around a unique, scalable format — the SEP Matching Events, which comprise of three activities: Matching, Mapping and Sharing.Matching- Through a series of international events where the best European startups have the opportunity to meet decision makers of corporates with a specific and concrete interest in procurement, investment and acquisition.Mapping- In parallel with the Matching Events, relevant information about startups will be collected.  The goal is to map the most interesting European startups and to track their performance and evolution.Sharing- SEP will identify key forms of support that leading European companies provide to scale startups, including corporate accelera
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Sources and atmospheric processing of carbonaceous aerosol in East Asia'.

assistant: **Concept**

High loading of carbonaceous aerosols from residential combustion of coal and wood fuels, traffic, industry, and biomass burning pollute the air of East Asia. The resulting Atmospheric Brown Clouds (ABC) are in wintertime warming the atmosphere yet dimming the surface in this vast region with severe impact on the climate, food and water security as well as air quality. Although these short-lived climate pollutant (SLCP) aerosols attract large interests across the science-policy interface, efficient mitigation actions are hampered by the limited understanding of the relative contributions of different sources of combustion-derived carbonaceous aerosols and of their subsequent atmospheric processing. Here the relative contribution from fossil fuel and biomass combustion will be quantified by molecular combustion markers and powerful isotopic fingerprinting, including microscale-14C dating of BC and OC aerosols. Aerosol samples will be probed from recently established Sino-Swedish observational program in the four populated and industrialization hotspots in China (North China Plain – Beijing; Yangtze River Delta – Shanghai; Pearl River Delta – Guangzhou; Szechuan Basin– Chengdu) and from the SE Yellow Sea recipient site on a Jeju Island (Korea Climate Observatory – Gosan), providing an ideal context for these investigations. The molecular/isotopic fingerprints of such synoptic aerosol samples provide integrated source signature and possibility to assess atmospheric processing during over-ocean long-range transport. This field quantification of BC and OC sources and processing in E Asia will contribute to (a) top-down observation-based test and improvement of bottom-up technology-based emission inventories (uncertain for small-scale and open combustion); (b) improved aeroso