RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Preventing Chronic wound infections with a novel, antibiotic Wound Irrigation Solution; relieving patients from pain, risk of amputations and ensuring large cost savings for all Healthcare Systems.' (WoundRinse) targeting Horizon 2020.

assistant: **Abstract**

Today, 40 million people globally live with chronic wounds. In addition to elevated pain, suffering and reduced quality of life for these patients, the direct cost for the national health systems of treating chronic wounds amounts to €47,8 Bn in UK and USA alone. Totally this corresponds to around €180 Bn per year globally. Frost & Sullivan (2017) estimates the total wound care product market to be €10 Bn. In total, biofilm infections represent 80% of all human infections and facilitate the development of antimicrobial resistance. All wounds are susceptible to microbial colonization and subsequent development of biofilm infections. SoftOx’ innovative Wound Irrigation Solution (WIS) is based on a combination of two highly active chemical agents with antimicrobial properties. The solution effectively stops microbial colonization and prevent biofilm formations in wounds, and thus enables the immune defense to regain control of the wound healing process. The proposed approach is based on successfully stabilizing hypochlorous acid with our patented production process and mixing device. Current SoA is not as effective in preventing biofilm infections without having adverse effects on the host. Our aim is to develop a clinically proven wound Irrigation Solution with antimicrobial effect and wound tolerability superior to all SoA products in the market.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The application of cdna microarray technology for unraveling molecular events underlying dormancy and cold hardiness in forest tree seedlings.' (COLDTREE).

assistant: **Concept**

Reforestation logistics and forest nursery management depends on the logical-logical status of the trees. Lifting and cold storage of insufficiently hardened trees leads to reduced vitality, frost damage and desiccation. Identification of molecular processes underlying winter hardiness will allow for the development of rapid and reliable tools to determine seedling condition. The powerful coda micro array technology will be employed to analyse gene expression patterns in economically and ecologically important forest tree species in combination with physiological and morphological screening. This multidisciplinary approach will result in a detailed picture of molecular events involved in the onset and release of dormancy and hardiness. Genes with a strong predictive value will be selected for future implementation in molecular hardiness tests that will aid in improving forestation planning and forest tree nursery management.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Geographic environments, daily activities and stress: a study on the space-time fragmentation of exposure patterns' (FragMent).

assistant: **Concept**

Stress is nearly ubiquitous in everyday life, and imposes a tremendous burden worldwide by acting as a major risk factor of mental disorders, autoimmune, infectious and cardiovascular diseases, and some cancers. The aim of the FragMent project is to evaluate to which extent the spatial and temporal fragmentation of exposures to environments in daily life influences physiological and psychological stress, as well as social inequalities in stress. Some evidence shows that exposures to daily environments may either act as a stress contributor or provide some stress restorative qualities. While the protective effect of greenness has been clearly established, strong uncertainties remain regarding the effects of urban environments. FragMent starts from this premise to investigate the environmental determinants of momentary, daily and chronic stress in relation with immediate, daily and regular environmental exposures. The project uncovers the role of spatiality and temporality in exposure effects on stress. It further builds on the concept of space-time activity fragmentation, to contextualize patterns of exposure within activity patterns. Finally, it analyses how differences in space-time exposures and activity patterns across social groups may lead to social inequalities in stress. An observational cohort study will be used to evaluate momentary, daily and chronic stress in daily life, using a combination of traditional web-survey, map-based questionnaires, smartphone tracking and Geographic Ecological Momentary Assessment. A series of lab-based experiments, combining Immersive Virtual Environments with a walking simulator, will assess the effect of urban environmental characteristics and the temporality of exposures on momentary physiological and psychological stress. Brid
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Foundations of Algorithmic Contract Theory' (FACT) targeting Horizon Europe.

assistant: **Abstract**

Algorithmic game theory (AGT) lies at the intersection of algorithms and incentives, offering a framework for the design of algorithms that provide incentives for collaboration in computational markets. AGT has played a pivotal role in shaping vital computing platforms. One of the most influential fields within AGT is algorithmic mechanism design, providing incentives for truthful revelation of private information.An equally important intersection of algorithms and incentives arises in the design of algorithms incentivizing self-interested agents to exert costly effort in executing their tasks. Incentivizing effort was studied with great success in the economics field of contract theory.As classic applications of effort incentivization move to computational platforms, including huge computational markets for freelancing services, marketing, and online courses, they grow in scale and complexity and become data-driven. In this evolving landscape, adopting an algorithmic approach to contract design is essential. This includes a language for analyzing the computational complexity of contracts in combinatorial settings, tools for studying simplicity-optimality tradeoffs, and a formalism for analyzing data-driven contracts.In 2006, I co-authored the pioneering paper applying an algorithmic lens to contract design, marking the inception of the field of algorithmic contract theory (ACT) and foreshadowed future developments. However, it is only in recent years that the scientific landscape and computational platforms have matured to a stage where ACT has become a prominent field in AGT. Preliminary research in ACT has been enlightening. However, the state of the art of ACT still lags far behind full applicability in Internet applications, largely due to disregard of crucial real
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Activation of vasculature associated stem cells and muscle stem cells for the repair and maintenance of muscle tissue' in the context of a Seventh Framework call.

assistant: **Objectives**

We propose to develop new strategies to mobilize skeletal muscle tissue-associated stem cells as a tool for efficient tissue repair. This will be combined with exploring novel approaches that limit tissue damage, and will focus on agents that modify muscle and muscle vasculature progenitor cells. These molecules include nitric oxide associated with non-steroidal anti-inflammatory drugs, HMGB1, Cripto, NAC, and present and improved deacetylase inhibitors. Three clinical trials will be run in tandem with efforts to dissect the underlying mechanisms of action. Importantly, we have already initiated a monocentric clinical trial that focuses on the efficacy of NO-donors plus NSAIDs in muscle pathologies. Our efforts will be complemented by novel biodelivery systems for effective targeting. Our efforts will be complemented by novel biodelivery systems for effective targeting. The most promising drugs, used alone or in combination, will be first validated in small and large animal models. Our project brings together leading investigators to examine how vascular and muscle progenitors participate in postnatal growth and muscle tissue repair. A key issue that this project addresses is the tissue environment in which endogenous stem cells are activated. We propose that muscle degeneration and fibrosis provokes altered vascularization and immune responses, which eventually affect negatively stem cell functions. Molecules that can be used to therapeutically target these key cells, and their communication with neighboring vascular, inflammatory and fibrotic cell types, will lead to more effective approaches to muscle regenerative medicine and to novel cures for degenerative diseases, including atherosclerosis, vascular damage in diabetes and in peripheral ischemic vascular disease.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Forming High-Temperature Solids in Protoplanetary Disks'.

assistant: **Innovation**

Strong evidence, regarding the properties and environment of chondrules and calcium-aluminium rich inclusions (CAIs) in the meteoritic record suggests that a local, transient heating mechanism is required to produce a significant amount of the solid material found in the solar system.  With the early solar nebula as a proxy for early solar systems in general, this heating process must then be a significant component to understanding the evolution of dust in protoplanetary disks in general. I propose to develop the theory of the short-circuit instability recently proposed by myself and my collaborators. This instability acts in thermally ionised plasmas such as significant parts of the midplane of a protoplanetary disk, and satisfies a range of established constraints on the formation of chondrules and Type B CAIs. We have already established that it attains the necessary temperatures, but to establish the correct parameter regimes for the onset of the instability, and the timescales of the heating and cooling requires significant computational modelling, which is the subject of this proposal.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Platform for Heterogeneous Integration of NEMS on ICs' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Within the ERC-M&M´s Starting Grant project (No.277879) we are exploring an innovative platform technology for wafer-level heterogeneous integration of integrated circuits (ICs) with micro/nano-electromechanical systems (MEMS/NEMS). This type of heterogeneous 3D integration technology is part of the More-than-Moore paradigm depicted in the International Technology Roadmap for Semiconductors (ITRS)  and allows the combination of standard CMOS-based integrated circuits and high-performance MEMS devices to form complex and highly integrated systems that are not possible to manufacture with other micro-manufacturing approaches. First heterogeneous integration platforms for IC-integrated MEMS products have already been commercialized with great success by InvenSense (USA) and by mCube (USA) in collaboration with TSMC (Taiwan), the world’s largest CMOS foundry. However, the established heterogeneous integration technologies have limitations with respect to the type of MEMS devices that can be realized and the extent to which the MEMS-ICs system component can be miniaturized. The heterogeneous integration platform developed in this ERC-M&M’s+2 Proof of Concept proposal is suitable for a variety of small-sized MEMS components with large-volume markets, including infrared (IR) detector arrays, micro-mirror arrays, ultra-low power circuits based on NEM switches (a specific target application are low-power FPGAs), gyroscopes, accelerometers, microphones, etc. Thus, the heterogeneous integration platform is addressing a potential multi-billion € market. In contrast to the competing technologies, our heterogeneous integration platform is enabling the integration of ICs and MEMS/NEMS devices with extremely small device dimensions in the nm-range, very small via dimensions in the sub-
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Automated Real-Time Broad Band Seismology in the Azores-Gibraltar region' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Earthquakes cause great damage to societies at all levels. Recognizing that geophysical observations are essential for the mitigation of natural disasters the Portuguese Foundation for Science and Technology (FCT) recently created the National Geophysics Network (RNG) – a geophysical monitoring network managed by a consortium of academic and non-academic national institutions. Project ART-SEIS aims at contributing to the mitigation of seismic risk in the Portuguese territory, taking advantage of the new research infrastructures of the RNG. We propose to develop an effective and sustainable seismic monitoring system that allows for the generation of near-real-time earthquake-information after an earthquake, and rapid response in case of disaster. In order to accomplish this overall goal, we have defined four specific objectives: 1) To develop a seismic system that will allow rapid response to earthquake disasters in Portugal by rapidly computing the earthquake location, magnitude, style of faulting and maps of ground shaking (shakemaps); 2) To implement a set of algorithms for high-quality estimate of earthquake parameters (hypocenter, magnitude and moment tensor) taking into account the specific geographic situation of Portugal; 3) To investigate and implement procedures that reduce the operational costs of the seismic networks using the available technologies (cheap and effective data transmission, automation of routines, etc) in order to render its operation sustainable in time; and 4) To advocate and promote the implementation of the solutions identified and developed in the project by the national authorities, in the scope of the recently created RNG. We propose to set-up this seismic system using state-of the-art software and techniques (e.g., use of SeisComP3 soft
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Engendered sport: A historical sociological study of doing and undoing gender in sport' (ENGENDEREDsport) targeting Horizon 2020.

assistant: **Abstract**

Why are sports segregated by gender? Why do women play some sports and not others? What makes gymnastics a feminine sport? Why shouldn’t men compete in synchronised swimming? Why didn’t women compete in Olympic weightlifting before 2000? These questions have gained renewed prominence in the wake of South African athlete Caster Semenya’s legal appeals against the decision by the International Association of Athletics Federations to reduce her testosterone levels, the ‘me too’ movement, revelations of years of abuse in women’s gymnastics, and the controversies around Laurel Hubbard’s transition from male to female and what it meant for her weightlifting career. These issues have cast a fresh spotlight on the gendering of sport which has created barriers to discrimination against women, and a range of psychological and health problems for women, especially young women.  This project employs historical sociology to understand how sports’ international governing bodies create, enforce, and dismantle gender segregation. It uses gymnastics, swimming, and weightlifting as case studies to compare how three sports have been engendered through their international federations’ rules and policies. Immersion in historical archives combined with qualitative interviews provide the data for the project, which will be analysed using a gender theory. In doing so, this project aims to provide a critical understanding of the binary gendering of sports as masculine or feminine, and offer new policy recommendations for sports associations to achieve greater inclusivity in sport. It will also expand the scientific skills of the researcher by incorporating sociological theory into history. It thereby broadens her expertise and reinforces a mature research position, improving the fellow’s employ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Decreasing Pancreatic Adenocarcinoma-related Inflammation using small molecule inhibitors of STING' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

We will develop and test a treatment for pancreatic ductal adenocarcinoma (PDAC). To this aim, we will synthesize and evaluate the efficacy of novel inhibitors of nucleic acid-induced inflammation that we have identified. Indeed, nucleic acid-induced chronic inflammation is a major driver of tumorigenesis. Because the canonical pathway that triggers nucleic acid-induced chronic inflammation relies on the STING protein, identifying ways to activate or inhibit STING is a major goal of current research. We have identified a novel endogenous pathway that antagonizes STING though the production of a second messenger molecule. This pathway prevents spurious STING activation and regulates nucleic  acid-associated inflammation. We have developed a set of analogues of this small molecules for wich we demonstrate the ability to prevent STING activation in vitro and now wish to ameliorate the intracellular delivery of these molecules to assess their in vivo efficacy on PDAC-associated inflammation. PDAC is a suitable model for establishing the proof of concept of efficacy of the treatment we propose, because we show that knocking-out STING impairs PDAC growth. Therefore, DIM-CriC will provide novel means to tackle STING-dependent inflammation in PDAC. Ultimately, this work should pave the way to assessment in additional tumorigenesis models that present a STING-dependent inflammatory profile, unraveling a novel route to block cancer-related inflammation to the benefit of patients.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Training for cAreer deveLopment in high-radiation ENvironment Technologies' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

TALENT is a 4-year multi-site training network aiming at career development of young researchers on design, construction, manufacturing, testing and commissioning of innovative radiation hard detector modules and novel scientific instruments. TALENT provides, to 15 ESRs and 2 ERs, training for deep understanding of the complexity of scientific instrument building from theoretical design until industrial manufacturing cost efficiency considerations. The network consists of 9 academic institutions and 8 industrial companies of excellence, providing the researchers a multicultural, truly stimulating and interdisciplinary learning environment.The 2006 report of ESFRI and the European Strategy for Particle Physics set the CERN Large Hadron Collider (LHC) Upgrade and enhancement of intersectoral R&D as priorities to keep the leading high energy physics facilities and expertise of Europe at the world-class level. TALENT will make substantial advancements into these objectives. The research program significantly contributes into CERN ATLAS R&D project, the Insertable B-layer (IBL). Furthermore, IBL’s innovative detector modules and instrumentation are already showing major potential for industrial applications in satellite instruments, X-ray systems, sensor technologies, medical imaging and cancer therapy. To enhance intersectoral R&D and training collaboration as well as mutual knowledge transfer, and thus to speed up the development of the IBL technologies, major R&D efforts within TALENT are put into these industrial applications.The mutual R&D interests the intersectoral consortium partners share is likely to lead into particularly creative multidisciplinary learning environment within TALENT. The chosen training approach will deepen the existing R&D collaborations between