RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Satellite-based services to support sustainable land use practices under the European Green Deal.' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

The main objective of GreenEO is to provide improved satellite-based environmental information to support sustainable nature protection practices across four competing land-use areas: cities, agricultural areas, forests, and ecosystems. Through combined exploitation of new Earth Observation products, digital infrastructure, and atmospheric and land surface models using machine learning and data assimilation, GreenEO will provide environmental information and stakeholder engagement practices to support the implementation of the Zero Pollution (ZP) and Biodiversity aspects of the European Green Deal (EGD). The project will serve as a proof-of-concept to enhance specific services provided by Copernicus and EUMETSAT in support of the EGD implementation. GreenEO aims to support the transition towards more sustainable land use practices in Europe and proposes a transformative governance system, relying on a data value chain enhanced with active stakeholder engagement and co-creation. The value chain proposes the uptake of satellite data, integrated in a modelling development chain and followed by value creation modelling applications. In cities, GreenEO will develop three satellite-based approaches of high-resolution urban-scale air quality maps to engage relevant stakeholders to support the ZP strategies. For agriculture, GreenEO will address impacts on nitrogen emissions, deposition, and biodiversity. It will create satellite-based high-resolution emission inventories, deposition, critical load exceedance maps, and identify areas with high recovery potential. GreenEO will develop a forest fire service that will revolutionize the monitoring of wildfires over Europe. GreenEO will create novel ecosystem monitoring indicators such as city greening indicators, ecosystem area and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Use of marine sponge cell culture (primmorphs) as bioreactor for production of bioactive sponge secondary metabolites.' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Modern cell culture (marine invertebrate cell culture) and bio production techniques (bioreactor) will be introduced in marine natural product research. Marine invertebrates will be used as bio factories for the synthesis of natural products with biomedical potential, such as compounds for the synthesis of natural products with biomedical potential, such as compounds possessing anti-cancer and anti-viral activity. This novel approach will also allow producing marine invertebrate secondary metabolites of industrial interest, notably avarol/avarone and aeroplysinin. The candidate will find benefit particularly by learning new techniques of search in molecular biology, biochemistry and cell culture. The development of bioassays on cell cultures shows a direct application in biotechnology. The project will be able to directly make the candidate qualified for a search for a work in University or in a company of biotechnology
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Activation Mechanism of a Glutamate Receptor' (2014-2020) under Horizon 2020.

assistant: **Objectives**

Glutamate receptors are amongst the most important signalling molecules in the brain. Activation of receptors by the neurotransmitter glutamate is required for nervous system function, underlying cognition, learning, memory and sensation. Despite advances in the study of their structural biology and physiology, how glutamate receptor complexes are activated remains unclear. With this proposal, we aim to determine how receptor activation and desensitisation are driven by glutamate binding. Our central approach is to map the motions of glutamate receptors during synaptic-like activity, in order to grab the frames needed to produce the movie of receptor activation. We aim to detect motion within the receptor on the angstrom scale by trapping conformational states during activation with artificial metal ion binding sites and disulfide bonds. Trapped receptors will be examined using biochemical measures of subunit association, biophysical reports of receptor activity and by structural biology. The results we obtain will be useful to rationally interfere with excitatory synapses in the brain and may therefore help the development of therapies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Creating the conditions for a combined R&D and demonstration project for the development of an objective mesh gauge', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

The main objective of the present proposal is to prepare a Combined R&D and Demonstration Project for the development of a new mesh gauge. This new mesh gauge should allow more reliable and objective mesh measurements than the present official EU wedge gauge used for inspection purposes.The specific objectives of the proposal can be formulated as:1) to seek partners (SMEs/instrument makers) for the development, construction and commercialisation of a new mesh gauge,2) discuss with these partners possible solutions for exerting a stable measuring force with the new gauge,3) to investigate the legal aspects of mesh size measurements for inspection purposes,4) to prepare and write a proposal for a Combined R&D and demonstration project for the development proper of a new mesh gauge.The proposal contributes to the improvement of tools and techniques for the implementation of the monitoring and enforcement of fisheries regulations. Description of the work (maximum 2000 characters).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'European malaria vaccine initiative' (EMVI), addressing dissemination and exploitation.

assistant: **Impact**

To contribute to the European Commission's Accelerated Action for Control of the Poverty Related Diseases by sustaining and expanding a European Clinical Trials and Development Platform for Malaria vaccines, enabling co-ordination of EC and EU efforts. To ensure international co-ordination and collaboration in malaria vaccines development and testing. To put in place a structure needed to ensure rapid and flexible reaction to technological and scientific breakthroughs in malaria vaccine development. To provide a mechanism for EU Member States' financial contributions towards achieving the common goal of developing affordable and accessible vaccines in endemic areas.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'MOBILE RESCUE PHONE' to be submitted under Fourth Framework.

assistant: **Abstract**

GSM mobile phones can greatly enhance the autonomy and quality of life of disabled and elderly people. The project aims to redesign and simplify existing mobile phones to meet the needs of such users, and make mobile phone services accessible to them, It will provide efficient access to emergency services, i.e. foolproof and fail-safe operating procedures, and ways of adding on equipment for hearing impaired users like text telephony, awareness of public alarms, speech intelligibility enhancement, and links to hearing aids, also reducing the interference of mobile phones on hearing aids. The result will be the Mobile Rescue (MORE) phone and system, using the GSM standard infrastructure.Existing public and private service centres will be upgraded with computer mapping equipment and software.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Personalized Environmental Service Configuration and Delivery Orchestration'.

assistant: **Objectives**

There is an increasing need to orchestrate environmental services located on the Web to enable personalised decision support or to provide tailored environmental information. The reasons are multi-fold, for instance, there is only a partial coverage of the environmental conditions given by one provider, however, the environmental information provided must be of high-quality standard. Furthermore, there are often contractual restrictions to provide complementary external data for the top parameters. Users also face contradictory information from several sources and difficulties in information assessment for decision making. Based upon recent works and the application of innovative technologies, PESCaDO significantly advances the state-of-the-art and aims at the following five objectives: 1. Consider alternative services on the Web or the best complementary service to be chained to their own service or to be used as a decision support service. 2. Assess the confidence in the service's data and offer reliable metrics of the degradation of data uncertainty in complex service node constellations 3. Enable dynamic selection and connection of nodes based on quality, content or the service chain configurations. 4. Integrate the user into the process of service orchestration and information delivery. 5. Treat service orchestration in connection with user decision support. PESCaDO develops environmental node discovery techniques based on advanced domain-specific Web search engines and multilingual analysis to derive the functional and qualitative coverage of the nodes. The reliability of the services and the uncertainty of the direct or propagated data will be assessed by confidence and data uncertainty metrics, among others derived from Fuzzy Theory. PESCaDO targets service orch
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Post Scriptum: A Digital Archive of Ordinary Writings (Early Modern Portugal and Spain)'.

assistant: **Objectives**

The project P.S. proposes to build up a campaign of systematic collection, edition and historical-linguistic study of personal letters written in the Early Modern Ages (17th to early 19th century) in Portugal and Spain. The documents in question are original epistolary writings made by servants, children, wives, lovers, thieves, soldiers, artisans, priests, political fighters, and many other types of social agents whose paths were crossed by the prosecuting ways of the Inquisition and the civil courts, two institutions that used to seize personal correspondence as instrumental proof. Since the documents are accompanied by the ‘sociological interviews’ carried out by inquisitors and judges, they allow researchers a well-contextualized study of traditional communities in their inter-personal modes of relation. The sources’ texts contain very frequently an (almost) oral rhetoric through which emotions were expressed, commonsense was stated, non-orthodox beliefs were confessed and trivial incidents were narrated. Until now, it has been difficult to discover more than thin samples of this Early Modern ‘popular’ discourse. The P.S. project will not only assemble a large collection of it, but it will also match its philological treatment – an online digital edition following Textual Criticism standards – with the cultural and linguistic study of its contents.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Candidatus Symbiodolus in Cryptocephalus beetles: unveiling the nature of this novel insect generalist symbiont'.

assistant: **Objectives**

Insects host various bacterial symbionts that can positively or negatively affect their fitness. While many symbionts coevolved within narrow host ranges, only a few generalist symbionts can colonize diverse insect taxa and tissues, with Wolbachia being the only well-studied example. The main aim of this project is to clarify the symbiotic nature of Symbiodolus (Enterobacterales), a newly discovered generalist symbiont infecting insects from six orders and colonizing various tissues. To investigate Symbiodolus' relationship with insects, the genus of phytophagous beetles Cryptocephalus (Coleoptera, Chrysomelidae), including both Symbiodolus-infected and uninfected species, will be used as a model. Specifically, the first project objective is to determine the prevalence and phylogenetic distribution of Symbiodolus within Cryptocephalus to define if it is a phylo-symbiont or if its association with the host is linked to other factors. It will be achieved by characterizing the bacteria hosted by different Cryptocephalus species and testing the phylogenetic signal of Symbiodolus presence/absence across the genus. The second objective is to determine Symbiodolus transmission mode by localizing it in Cryptocephalus body across developmental stages and within its excretions using fluorescence in situ hybridization. The third objective is to assess Symbiodolus impact on Cryptocephalus fitness by analyzing the genomes of strain/s infecting six Cryptocephalus species to determine the presence of genes related to host benefits, pathogenicity, and reproductive manipulation. Symbiosis manipulation experiments will also test the effects of selectively removing or introducing Symbiodolus on the host phenotype. Beyond clarifying Symbiodolus' symbiotic nature, this project will provide
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Childhood body size, growth and pubertal timing and the risk of cancer in adulthood' (CHILDGROWTH2CANCER), addressing dissemination and exploitation.

assistant: **Impact**

The goal of the proposed research is to examine how the independent and combined effects of childhood adiposity (assessed by body mass index [BMI]; kg/m2) height, change in BMI and height, and pubertal timing from the ages of 7 to 13 years are associated with the risk of cancer incidence in adulthood. Greater body size (adipose tissue and different types of lean tissue) reflecting past or ongoing growth may increase the risk of cancer in individuals as greater numbers of proliferating cells increase the risk that mutations leading to the subsequent development of cancer occur. As childhood is a period of growth, it is plausible that it is of particular relevance for the early establishment of the risk of cancer.Data from the Copenhagen School Health Records Register, which is based on a population of schoolchildren born between 1930-1983 and contains computerised weight and height measurements on >350.000 boys and girls in the capital city of Denmark, as well as data from other cohorts will be used. Survival analysis techniques and the newly developed Dynamic Path Analysis model will be used to examine how body size (BMI and height) at each age from 7 to 13 years as well as change in body size during this period is associated with the risk of multiple forms of cancer in adulthood with a simultaneous exploration of the effects of birth weight and pubertal timing. Additionally, potential effects of childhood and adult health and social circumstances will be investigated in sub-cohorts with this information available.Results from this research will demonstrate if childhood is a critical period for the establishment of the risk for cancer in adulthood and will lead into mechanistic explorations of the associations at the biological level, investigations into associations be
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Remote controlling biological systems by sonopharmacology and sonogenetics' (SONOPHARMAGEN).

assistant: **Innovation**

To date, light has been employed as a widespread trigger to achieve control over the activity of drugs and protein function establishing the fields of photopharmacology and optogenetics, respectively. Both techniques led to promising new therapies, the elucidation of brain function or understanding of neural disorders. However, serious limitations resulting from the low penetration depth of light into tissues are severely hampering progress in these fields. In contrast to photons, ultrasound deeply penetrates tissue and can be applied with sub-millimeter resolution and consequently has been widely established in the clinic over many decades for therapy and diagnostics.In this ERC Advanced Grant, I will develop a radically new approach to control the activity of drugs, proteins and genes by biocompatible ultrasound. Polynucleic acid carriers, which can bind a wide variety of bioactive payloads, will be designed to be sensitive to different ultrasound sources, which can be applied in clinical settings and do not harm cells or tissues. Upon ultrasound irradiation, these carriers liberate their bioactive payloads by mechanochemical principles to switch on drugs and control cellular functions. To achieve this aim, I will: investigate the effect of ultrasound (US) on nucleic acid architectures; study the loading of polynucleic acids with different payloads and their release by US; develop a technology platform to activate small molecule drugs, proteins and oligonucleotides; and showcase the huge potential of these technologies for cancer immunotherapy, diabetes research and tissue engineering.This project will boost sonopharmacology and sonogenetics. Its outcomes will enable spatiotemporal control of drug action to minimize side effects in pharmacotherapy like cancer. The rem
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Bentonite Erosion: effects on the Long term performance of the engineered Barrier and Radionuclide Transport (BELBaR).'.

assistant: **Concept**

Recent safety assessments nuclear waste repositories have shown that the formation and stability of colloids may have a direct impact on the overall performance of the repository.The main aim of the BELBaR project is increase the knowledge of the processes that controls clay colloid stability, generation and ability to transport radionuclides. The overall purpose of the project will be to suggest a treatment of the issues in long-term safety assessment.The key areas of research will be:•erosion of bentonite buffers, the main objective of these studies will be to understand the main mechanisms of erosion from the bentonite surface and to quantify the extent of the possible erosion under different conditions•clay colloid stability studies under different geochemical conditions. The colloids formed at the near/far field interface would be stable only if favourable conditions exist and therefore their relevance for radionuclide transport will be strongly dependent on the local geochemical conditions•interaction between colloids and radionuclides and the host rock, how colloid mobility may be affected be the composition of the host rock and the mechanism of sorption and de-sorption of radionuclides on the colloidsIn these areas substantial laboratory studies will be undertaken.The modelling studies will support the laboratory studies through development of conceptual and mathematical descriptions of the observed phenomena.The final outcome is to consider how colloids and related phenomena can be considered in the long term safety case and to make recommendations on how the safety case could pursue to address this potentially very significant issue.The project will have strong focus on cooperation and integration. This will be achieved by exchange of staff between partners an