RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Effective recycling of Rare Earth Elements from End-of-Life products for European Circular Economy' (EFESTO4EU), addressing dissemination and exploitation.

assistant: **Impact**

Raw materials are pivotal in realizing the United Nations' '2030 Agenda for Sustainable Development' and its 17 Sustainable Development Goals. Among these critical raw materials (CRMs), are of strategic importance to the EU's economy. However, they face significant supply risks, particularly Rare Earth Elements (REEs), vital in emerging clean technologies. Dependence on REE imports, coupled with geopolitical instability, has driven price spikes, prompting the need for recycling. Currently, no commercial recycling operation exists for end-of-life (EoL) products and their REE content, potentially exacerbating supply-demand imbalances. Recycling CRMs offers environmental benefits, reducing mining's impact, enabling multiple CRM recovery from a single device, and minimizing habitat disruption and water pollution. EFESTO4EU project seeks to advance scientific understanding and develop innovative materials for metal extraction, primarily focusing on recycling REEs from real EoL products using environmentally sustainable technologies. The proposed method involves extracting REEs from the leachate resulting from the pre-treatment and dissolution of EoL products. This process employs a solid/liquid system, utilizing Ionic Liquids (ILs) immobilized on silica-based gel to form a material referred to as ionogel. Subsequently, these ions are released and reclaimed, allowing for the reuse of ionogel in successive cycles. The project has a strong interdisciplinary approach going from material synthesis to solution thermodynamics. To ensure the successful implementation of these project goals, I will conduct my research at Swiss Federal Laboratories (Empa) and University of Udine (Italy), under the guidance of Dr. Wim Malfait and Prof. Andrea Melchior, leading scholars. This project wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Investigating the role of the immune system in the development of fibrosis in the lung' in the context of a Seventh Framework call.

assistant: **Objectives**

Chronic lung disease is a very common cause of morbidity and mortality across Europe.  For example, chronic obstructive pulmonary disease (COPD) causes over 30,000 deaths/year in the UK with a rising incidence and it is estimated that by 2020 COPD will become the third leading cause of death and the fifth leading cause of chronic disability worldwide.  In the EU approximately 41,300 lost work days per 100’000 population are due to COPD while productivity losses amount to €28.5 billion annually and patient care totals €10.3 billion annually.  To date, therapies to limit/reverse fibrosis in the lung have failed to provide long-term beneficial effects and new therapeutic targets are desperately needed.  The work proposed in this application will allow me to investigate the role of the immune system in general, and more specifically the macrophage, in fibrosis and identify new therapeutic targets.  The themes highlighted in this proposal complement priority areas identified within the FP7: Health program including Innovative therapeutic approaches and intervention and Translational research in major diseases.  In this fellowship I will investigate the role of cellular immunity and in particular the macrophage in orchestrating the environment in the lung that determines the fibrotic response to injury.  I will investigate whether specific macrophage phenotypes contribute to loss of function by driving aberrant epithelial repair and fibrotic remodeling in the lung.  I hypothesis that manipulation of lung macrophage phenotype by treatment with azithromycin may limit fibrosis in the lung.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Proximity Network Assay: driving the future of high-resolution protein interactomics in 3D for precision medicine, drug discovery, and molecular diagnostics' (PNA) under Horizon Europe.

assistant: **Objectives**

Pixelgen Technologies, a deep-tech Swedish life sciences company, pioneers innovation in spatial proteomics and interactomics, critical for precision medicine, cancer research, and drug discovery. Building on the success of its Molecular Pixelation (MPX) technology, Pixelgen introduces the Proximity Network Assay (PNA), enabling high-resolution, high-throughput protein mapping. The PNA technology addresses current limitations in spatial proteomics and interactomics:low resolution, scalability challenges, and high costs of traditional microscopy-dependent methods.PNA technology employs a unique DNA-based approach, achieving an unprecedented 30 nm resolution and multiplexing over 150 targeted protein markers in a single assay. Diseases are caused by aberrant cell function. These functions are executed by protein interactome dynamics, currently not studied at scale. PNA will allow researchers to assay intricate protein interactions at both cellular and subcellular levels (including cell-to-cell interactions and FFPE tissues), unlocking insights into immune responses, drug mechanisms, and disease pathology. PNA eliminates the need for expensive and low-content optical imaging systems, providing a cost-effective and accessible solution for academic and industrial applications. PNA is currently at TRL6, with proof-of-concept data generated for key use cases. The EIC Accelerator project aims to develop PNA to TRL9 by advancing reagent development, creating optimised sample preparation protocols for FFPE tissues and cell-to-cell interaction studies, and enhancing data processing software for seamless integration with multi-omics platforms. PNA technology will redefine spatial proteomics, enabling groundbreaking research and fostering Europe’s leadership in the biotechnology sec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Mediterranean and Eastern European Countries as new immigration destinations in the European Union' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

The Amsterdam Treaty introduced a new Community policy on immigration and asylum. Its objectives were defined in Tampere by the European Council which stressed the need for more efficient management of migration flows at all their stages. The management should address various forms of migrations and be exercised by means of various instruments in the countries of destination and origin. Thus, the creation of European immigration policy becomes a complex process of co-ordination of national policies with the Community objectives. Amongst diverse migration trends in Europe, the emergence of new immigration countries seems particularly important. The transition of migratory status followed economic development induced by the participation in the common European market and political stability. The socio-economic conditions of the change as well as policy responses to the new situation varied considerably between the countries of North-western, Southern and Eastern Europe and led to various structures of immigration and impacts on labour markets. These differences provide interesting research basis which could shed light on the immigration mechanisms in Europe. In this 30-month project, the consortium of scientific institutions from 9 EU states, all with tremendous experience in migration research will analyse the causes, characteristics and impact of migratory flows in the new European immigration destinations - Southern and Eastern Europe, and with reference to the established" European immigration countries. Comparing the migrations and relevant policies will facilitate identification of similar challenges and transfer of experiences. The analysis will address historical, political and economic background of migration processes and its final goal will consist in preparati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Inside the big black box analysing visits to physics laboratories'.

assistant: **Innovation**

The project aims at analyzing the impact of visits to important physics laboratories on the lay public, using the results to produce guidelines with a view to improving the communication efficiency of such centers. The project will entail the participation of laboratories that organize on a regular basis a program of public visits - and in particular the staff dedicated to its planning and management - as well as experts in public communication of science and in the evaluation of communication activities at universities and research centers. The project will thus take the form of a research-intervention path, its actors being not only the subjects directly involved in the planning and implementation of communication activities at the laboratories, but also sociologists, psychologists and anthropologists, building a collaboration with the aim to devise best practices for public communication of science performed through direct contact between scientists and the general public on the same premises where the scientists usually do research.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Light-Field Controlled Molecular Reactions' in the context of a Horizon 2020 call.

assistant: **Objectives**

It is a long-held dream of physical chemists to not only study, but also fully control chemical reactions. The research aim of this project is to control such reactions using the photon catalysis method. This technique uses a focused, high-power, non-resonant pulsed laser to create a high electric field. This field can interact with the dipole it induces in a molecule. With this so-called dynamic Stark effect, we can alter energy levels and potential energy surfaces of the molecule under study and thereby control the chemistry in the system. Our first goal is to apply this relatively new and state-of-the-art technique to control the chemistry in a small benchmark molecule. This will serve as a proof-of-principle experiment and give us a better understanding of the technique and the molecular mechanisms it affects. Afterwards, our aim is to control conical intersections in relatively large biochemically relevant molecules and to create light-field assisted molecular switches. The experiments will be conducted in a molecular-beam machine. Three lasers will interact with the molecules. The first one will provide the high electric field to control the chemistry, the second laser will excite the molecules and thereby start the chemical reaction, and the third one will ionize the reaction products. The resulting ions and electrons will be recorded using the velocity map imaging technique. We will use state-of-the-art combinations of detection methods to elucidate the controlled chemical reactions in a very high level of detail. The photon catalysis method has the potential to become a relatively easy to implement and general technique that could advance many experiments from the level of understanding to the level of controlling molecular processes. It allows us to manipulate
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Effects of Eutrophicated seawater on rocky shore ecosystems studied in large littoral mesocosms'.

assistant: **Objectives**

The overall objectives of the EULIT project are to predict the response of rocky shore ecosystems to increased nutrient availability by (1) modelling the changes in ecosystem processes, (2) evaluating the increased production of herbivores, (3) assessing effects on growth responses of key organisms, and (4) predicting the resulting ecosystem structure and metabolism. In doing so, EULIT would allow the formulation of tolerable nutrient inputs to coastal waters, and to evaluate the capacity of increase' production of animal protein as a side benefit of the buffering effect exerted by herbivores. The project address the following intentions: (1) To improve the health of the coastal ecosystem and environmental management. (2) To understand the coastal ecosystems necessary to advance the sustainable use of the living marine resources. (3) To answer needs of European industry in the fields of marine exploitation. (4) To create synergy between research groups. (5) To take advantage of the partners network, ensuring a good integration of environmental protection issues. Eight basins (mesocosms) are constructed for littoral community experiments. Changes in ecosystem structure and flow of energy and matter will be measured by biomass and abundance of plant and animal communities, organismal size spectra, biodiversity, chemical analyses and metabolic measures. The link between subsystem measurements and the whole system behaviour in the mesocosms is regarded as an outstanding feature. Population responses as causes of ecosystem change will be measured as growth and productivity of all important plant components and metabolism, growth and reproductive effort of the most important fauna groups. Plant-grazer interactions will be studied in relation to nutrient richness in the system
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Unraveling bacterial glycosyrin as a master manipulator of plant glycobiology'.

assistant: **Innovation**

The apoplast is a critical battlefield where host immunity and microbial virulence collide. Plants rely on pattern recognition receptors (PRRs) and defense metabolites to sense and restrict microbial invasion, while pathogens evolve countermeasures to subvert these processes. Recent studies revealed that Pseudomonas syringae secretes glycosyrin, a unique iminosugar that promotes virulence by targeting the plant-secreted β-galactosidase BGAL1. BGAL1 is required for releasing the immunogenic flg22 epitope from glycosylated flagella, and glycosyrin blocks this process by inhibiting BGAL1. Beyond this specific role, emerging evidence implys that glycosyrin can broadly interfere with host glycobiology, potentially disrupting immune receptor maturation, blocking defense hormone release, and directly enhancing pathogen fitness.This project aims to establish glycosyrin as a multi-faceted virulence factor that reprogrammes plant glycobiology to undermine immunity. Three objectives will be pursued: (1) reveal how glycosyrin deregulates immune receptor function through altered glycosylation and reduced receptor accumulation; (2) demonstrate how glycosyrin suppresses the release of salicylic acid from inactive conjugates, thereby dampening systemic immunity; and (3) determine how glycosyrin promotes osmoprotection by inducing the accumulation of apoplastic osmolytes that enhance pathogen survival under stress. These objectives will be addressed through a multidisciplinary strategy integrating receptor biology, proteomics, metabolomics, and functional infection assays. By revealing glycosyrin as a molecular weapon that hijacks glycosidase-dependent processes, this work will redefine how bacterial metabolites can manipulate host immunity. The results will deliver a step-change in our
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'The Platform for Sharing, Initiating, and Learning Citizen Science in Europe'.

assistant: **Concept**

Citizen Science is a rapidly expanding and diversifying field of innovation with significant implications for, and potential benefits to, society, policy, and various academic research areas. This heterogeneity leads currently to a fragmented and not fully coordinated European Citizen Science landscape. The ambition of EU-Citizen.Science is to build, fill, and promote a sustainable platform and mutual learning space providing different tools, best practice examples and relevant scientific outcomes that are collected, curated, and made accessible to different stakeholders, ranging from interested citizens over scientific institutions up to politicians and public media in order to mainstream Citizen Science in Europe. This breakthrough will be pursued through three interconnected lines of activity: (i) coordination of citizen science actions and leveraging of existing resources in the presently fragmented landscape of Citizen Science in Europe, (ii) engagement of quadruple helix stakeholders at all levels (local, national and European), and (iii) creation of a mutual learning space and a set of comprehensive co-designed training modules for the different target audiences. Moreover, following a transparent, open and inclusive approach, EU-Citizen.Science will promote interdisciplinary, cross-border, cross-sector collaboration, and give rise to significant social innovation and new business models through the creation of new partnerships and the provision of novel sustainability-supporting tools. The EU.Citizen.Science project involves 14 partners and 9 third parties, representing 14 European Member States and a variety of stakeholders ranging from universities, NGOs, local authorities, CSOs and natural history museums, along with several other project supporters. Many of t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Kefa, a potassium efflux system in escherichia coli - molecular organisation and regulation of kefa locus, and structure characterization of kefa products' (1994-1998) under Fourth Framework.

assistant: **Objectives**

Regulation of potassium pool is essential for survival of bacteria submitted to hyperosmotic conditions. The potassium efflux systems KefA and KefD are believed to play a major role in regulating the potassium pool in Escherichia coli. The KefA system has been identified and cloned in the laboratory of Professor Booth in Aberdeen. The kefA locus has been sequenced and encodes three possible open reading frames. We will analyse the function of the three ORFs to determine which are responsible for KefA activity. The kefA products will be characterized in term of topology, cellular localization and activity. The regulation of ketA transcription and tlanslation will be studied by using gene fusion technology and primer extension. The influence of several factors on the activity of kefA, such as genetic background, medium osmolarity, growth phase and osmoprotectants presence will be investigated. The physiologic role of kefA will be studied by using defined kefA mutations created by reverse genetics.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Boosting innovation agencies for bioeconomy value chains' (BIOBoost) targeting Horizon Europe.

assistant: **Abstract**

The overall objectives of the BIOBoost project are to increase the latent potential of the participating innovation agencies, to learn from leading innovator regions, and to cement this knowledge and experience in the organisations, building and expanding networks, expanding the cooperation and enlarging the participation of more diverse innovation stakeholders and territories to existing successful initiatives in the bioeconomy, including agri-food, forestry, bio-based chemicals, materials and products, and bioenergy. The partnership will implement a range of activities via peer-to-peer learning, including study visits and staff exchanges, to develop closer relationships within the partnership, and with the wider regional innovation ecosystems, as well as to learn improved innovation support measures.  These will be cemented via operational work to build and develop innovation ecosystems and SMEs via hackathons and challenges (160 organisations involved),  by providing direct SME support on innovation management (24 cross-border KAM cases), and helping widening country SMEs towards financing of innovation projects (50+ cases). Over 450 SMEs will be engaged with during the implementation of the project, which will include active cooperation with 20 other innovation ecosystems. BIOBoost connects 7 homogenous EU regions in terms of similarities of RIS3 and S3 Platform synergies related to bioeconomy and digitalisation. The multidisciplinary partnership has been strategically selected, to work in  an inclusive and interactive bottom-up process, to discover potential new activities, and identify new opportunities that emerge from this interaction. Despite the homogeneity in terms of regional smart specialisation, the consortium consists of partners with a wide variety of co