RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Photoresponsive spin-crossover liquid crystals' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

This proposal aims at developing a series of photoresponsive magnetic soft materials through the combination of spincrossover (SCO) property, photochromic property and liquid crystal (LC) property in a single material. The SCO property comes from the switchable electronic state between high-spin (HS, S = 2) and low-spin (LS, S = 0) state of the Fe(II) center in an octahedral coordination sphere under an external stimuli (e.g. temperature, light and pressure) and display an interconversion between diamagnetism and paramagnetism. The SCO molecules will be further decorated with long alkyl chains, which are covalently inserted by azobenzene group as photochromic unit, to display both LC and photochromic properties. The reversible cis/trans conformational change of photochromic unit is expected to change the coordination sphere of Fe(II) center and intermolecular interactions in LC systems, thus tuning the ligand field and SCO cooperativity and giving novel ligand-driven light-induced spin change effect (LD LISC) behavior. Moreover, if compared to traditional solid crystalline materials, the obtained materials will show superior characteristics, such as reversibility, faster response, and improved fabricability, allowed by the flexible nature of LCs. The obtained photoresponsive SCO LC materials will have multidisciplinary applications in prototypes of optical memory devices, displays, sensors, and switches, etc. The proposal designed by the researcher and host will make a contribution and promotion in the development of multifunctional molecular magnets, especially of photomagnetic materials.


**Keywords:** Spin-crossover, SCO, Liquid crystal, LC, Photochromism, Photomagnetism, LD LISC, Azobenzene
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'NANOmetric bio-inspired coating for wind turbine WINGS ice protection' (Nanowings) under Horizon Europe.

assistant: **Objectives**

Although winters are the best season for wind energy harvesting, icing is a major problem affecting the competiveness of this type of renewable energy. In Europe, about 94% of the windfarms have suffered icing events, which reduce turbine performance and causing even temporary shutdowns. Indeed, icing-induced power output losses in wind farms are found to reach over 20% of the annual production. There is not yet an efficient, cost-effective anti-icing or de-icing solution on the market: active solutions (thermal and mechanical systems) present low efficiency while passive technologies (typically coatings and paints) are not easily applied, and their durability and effectiveness are not well demonstrated. Nanowings will overcome the icing challenge by developing a disruptive transparent nanocoating (super-glue polymers and nanoparticles blended formulation) with outstanding anti-icing and anti-fouling properties that can be applied in-situ via an innovative, portable, and light module (mini-electrospinning and heating system) which can be mounted under a remotely controlled drone. 5 g/m2 of the nanomaterial coated over the surface of a fiberglass-reinforced polyester or epoxy wind turbine blade creates a nano-rough layer (0.5 µm thick) that reduces the wettability of the surface and imprint self-cleaning properties. By avoiding ice accretion, Nanowings reduces downtimes and increases the electricity production of the wind turbine.  Nanowings is seizing a new concept of engineering and electrospinning of nanomaterials demonstrated at lab scale by partner LINARI. Moreover, the international consortium brings together top-notch academics (DTU) with seminal contributions in advanced nanomaterials and wind turbines performance under icing conditions; a well-recognized utility
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Cellular substrate of abnormal network maturation in neuropsychiatric disorders' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The long-lasting burden of major neuropsychiatric disorders results from disruption of cognitive performance in daily life. Impairment of long-range coupling between prefrontal cortex and hippocampus represents the substrate of disease-specific mnemonic and executive deficits. While it has been hypothesized that this impairment emerges long before the first clinical symptoms, technical and ethical limitations of non-invasive investigations in high-risk infants precluded the elucidation of ontogenetic mechanisms underlying the pathophysiology of disease. In previous studies, I pioneered the investigation of long-range coupling in the immature brain by developing a multidisciplinary approach that combines electro- and optophysiology in vivo with behavior, anatomy and analysis of network dynamics. Using mouse models of disease’s etiology, we recently identified the de-coupling of prefrontal-hippocampal networks during early development as potential mechanism underlying adult circuit dysfunction. These findings represent the basis for the current proposal, which aims at understanding the cellular mechanisms accounting for abnormal network maturation in neuropsychiatric disorders. First, the role of excitation/inhibition imbalance in the neonatal prefrontal cortex for disease-specific network impairment will be assessed. Second, the synaptic organization and wiring deficits within neonatal prefrontal-hippocampal networks will be monitored. Third, the cellular substrate of abnormal hippocampal activity causing weaker prefrontal-hippocampal interactions will be ascertained. Finally, the identified cellular elements underlying early network dysfunction will be selectively manipulated to rescue the juvenile circuit function and behavioral performance. Understanding the mechanism
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Advanced Infrastructure for Knowledge Based Services for Buildings Restoring'.

assistant: **Innovation**

Increasing number of complex works in buildings restoration/maintenance urgently requests an advanced and systematic access to the relevant knowledge. A highly promising approach to enable such an access and to foster advancing of construction industry SMEs toward the knowledge organisations are innovative forms of collaborative knowledge&business networks of SMEs and RTD partners. The innovative solutions for (a) collaborative SME-RTD communities for knowledge creation/reusing along the common work, to assure also a bidirectional learning (SMEs from knowledge funds and RTDs, and RTDs from collaborative work and ""tacit-inherited"" SME knowledge), and (b) closer business collaboration among SMEs and RTDs, are needed to assure higher efficiency of the knowledge-based approach spreading, resulting in creation of new full services with a high added value for clients. The project plans to develop ICT solution, suitable for SMEs to include (1) innovative, competitive knowledge and training providing services, and (2) support for realisation of new forms of SME-RTD networking through a specific knowledge integration. SOA-based platform will be developed in which KM services for collection, structuring and reuse of relevant content will be complemented by services for Management of Social Interactions (MSI) for realisation of virtual collaborative networks, and Technology Enhanced Learning (TEL). Main innovation is provision for the first time of a holistic, highly harmonised solution to achieve a strategic breakthrough in SME-RTD collaboration in a specific construction industry domain by (1) methodology addressing innovative SME-RTD network models, and methods/procedures for identification, collection and structuring of the specific knowledge for buildings restoration/mainte
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'NET ZERO PATHWAY RESEARCH THROUGH INTEGRATED ASSESSMENT MODEL ADVANCEMENTS' under Horizon Europe.

assistant: **Concept**

The ambition to achieve the Paris Agreement goals has led to the realization that a rapid and full decarbonization of the economy is required, involving a structural transition of the current economy and society. With the rise of quantified policy targets, policy packages, and consideration of multiple dimensions and sectors, Integrated Assessment Models with their ability to consider complex relationships and provide calibrated numerical results have become ever more important in the last decade. The PRISMA project aims to bring these models to the next level by focusing on four key areas of improvement, namely the representation of distributional justice and efficiency, innovation and finance, climate impacts and land-use implications, and lifestyle change and circularity. In these four key areas we will improve existing large-scale IAMs and sectorial models, and consider the linking of different models where applicable. Two cross-cutting shared themes across these areas are the improvement of the temporal and spatial resolution of the analysis, and the representation of disruptive and structural change in the economy. Notably we will increase the spatial granularity with a focus on Europe, and look at the yearly and in particular near term detailed modeling of rapid decarbonization pathways. The extensive model development will be co-designed through an interactive stakeholder engagement process from the beginning, and focus on model openness and usability to ensure the stakeholder and policy relevance. Moreover, PRISMA will focus in its application on the analysis of the spectrum of Fit for 55 package policies of the EU developing focalized robust and resilient Net zero pathways and assess the uncertainty around key variables and outcomes. PRISMA will also provide k
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'deTeRmine the trUe dEpth of DeEp subduction from PiezobaromeTry on Host –inclusions Systems' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

Subduction of one tectonic plate below another is the primary cause of catastrophic geological events such as earthquakes and explosive volcanism that directly impact thousands of kilometers of coastal and mountain areas located on convergent margins.  Real-time geophysical or seismic data only provide static snapshots of these subduction zones today. Therefore, quantitative understanding of the rates and true depths of subduction can only be achieved by determining the pressure-temperature-time-depth histories of Ultra-High-Pressure Metamorphic (UHPM) rocks that have been subducted to pressures greater than 3 GPa and subsequently exhumed. Conventional mineral thermo-barometry is severely challenged in UHPM terraines and thus the mechanisms attending the downwards transport of crustal material, and its return back to the Earth’s surface (exhumation), are still a matter of vigorous debate.The TRUE DEPTHS project will develop X-ray diffraction analysis of the anisotropic elastic interactions of inclusion minerals trapped inside host minerals. I will develop non-linear elasticity theory to provide a method that will be uniquely able to determine whether significant deviatoric stresses are recorded by UHPM rocks. By applying this method to samples from carefully selected field areas, I will be able to determine if metamorphic phase equilibria represent the true depths of UHPM, in which case subduction to depths in excess of 90 km must occur. Alternatively, quantitative measurements of large deviatoric stresses could indicate that tectonic over-pressure can account for the observed phase equilibria, thus not requiring deep subduction. If overpressurized domains are present in tectonically thickened lithosphere, they may represent a driving force for stress release leading to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'High performance variable solar control glazing' (1994-1998).

assistant: **Concept**

Objectives The present project seeks to show the feasibility for the manufacturing of a solid-state variable transmission glazing based on the phenomenon of electrochromism. The resulting device has memory and can be electrically controlled to obtain gradual but reproducible changes in optical properties through the visible and near infrared range of wavelengths. This can be performed manually or computer controlled as part of the energy management system in buildings. Technical Approach This is the third phase of an ongoing project started in 1989. The result of the previous two phases of this project has been to demonstrate suitable materials for the construction of a five layer device. In particular an electrochromic coating, a counter-electrode (or storage layer) and a polymeric electrolyte have been established with electrochromic efficiency of the order of 30 cm2/C, a charge capacity in excess of 20 mC/cm2 and ionic conductivity of between 10-5 to 10-4 Siemens/cm respectively. In addition good life time and durability have been shown in small area (100 mm x 100 mm) devices and a technology demonstrator with the same area has been constructed with performance close to that envisaged for a commercially viable product. Device design and more specifically, coating design will be explored in an attempt to optimise solar control performance . This will include the use of the near infrared absorption inherent in this type of device as well as the use of variable near infrared reflectance, obtained in highly crystalline materials. Life time assessment will form a major part of the investigations (Pilkington) and electrochemical assessment (Southampton) will be a crucial topic needed for establishing key mechanisms and parameters giving rise to device performance. In addit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'A Device for Phage Capture and Release'.

assistant: **Concept**

Bacteriophages are viruses that specifically infect bacteria and offer powerful solutions for combating antibiotic resistance, advancing industrial biotechnology, and enabling fundamental research. Major challenges hinder the broader use of phages in therapy and biotechnology. Identifying suitable phages and assembling complementary cocktails remains slow, labor-intensive, and largely unsystematic. Purification is equally problematic, as production in bacterial hosts introduces endotoxins, DNA, and other contaminants that are difficult to remove with current methods, which are inefficient, slow, and not scalable. Together, these obstacles represent critical bottlenecks and highlight the urgent need for reliable, rapid, and safe phage capture technologies.The PhageTRAP project aims to establish the proof of concept for a modular platform that can selectively capture and release phages using synthetic motifs tethered to a solid support. Different motifs will target Gram-positive pathogens, while other motifs will serve as examples for the customizable capture of Gram-negative pathogens. The platform will be validated with species clinically relevant for phage therapy and tested on phages recovered from environmental sources. By combining synthetic chemistry and microbiology, this proof-of-concept project will demonstrate a highly innovative, scalable, and safe approach to phage capture, enabling high-throughput screening, assembly of complementary phage cocktails, and production of therapeutic-grade preparations. The resulting platform has strong translational potential, clear industrial and clinical applications, and opportunities for commercialization and intellectual property development. Ultimately, PhageTRAP could become a disruptive technology for advancing phage-ba
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Investigation of the molecular mechanisms ensuring precision and reproducibility of Sonic Hedgehog mediated patterning in the vertebrate ventral neural tube' (NEURALNETWORKNOISE) under Seventh Framework.

assistant: **Objectives**

Morphogens are locally produced molecules that act over long distances in tissues to control the pattern of gene expression. A particularly well-understood model system for studying the mechanisms of morphogen-mediated patterning is the vertebrate neural tube. Here, Sonic Hedgehog (Shh) induces discrete neuronal progenitor domains through regulation of a combinatorial code of transcription factors. The observed precision and reproducibility of gene expression appears greater than can be accounted for by the precision of Shh signalling alone. Thus, mechanisms must exist that filter signaling noise. We hypothesize that this involves either the properties of the downstream transcriptional network regulated by Shh signaling or active cell sorting.The proposed research project aims at quantifying the amount of noise in the pattern of gene expression in the vertebrate neural tube, and investigating how, at which level, and to which extent this noise is buffered. To achieve this goal, I will generate fluorescent reporters for the expression of three key Shh target genes, Nkx2.2, Olig2 and Pax6, and spatiotemporally correlate the activity of these reporters with Shh pathway activity. In parallel, a quantitative analysis of the behaviour of cells will be performed to elucidate the contribution of differential cell adhesion and active cell sorting. The combined results will be integrated into a theoretical framework to account qualitatively and quantitatively for Shh-mediated patterning of the neural tube.Due to the iterative deployment of Hedgehog (Hh) signalling during animal development and the evolutionary conservation of the Hh pathway, the types of mechanisms deduced from our quantitative analysis will probably not only apply to Shh-mediated patterning in the neural tube, b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Nanohelicoid metamaterials templated by cellulose nanocrystals with end-tethered polymers' (CELICOIDS).

assistant: **Innovation**

Chirality plays a fundamental role in natural sciences and pharmacology. The ability to detect chiral molecules relies heavily on inherently weak circularly polarized light-matter interactions. Such interactions are enhanced in the presence of chiral metamaterials, which exhibit extraordinary electromagnetic properties not observed in nature. To date, large and broadband circular dichroism in the UV-visible spectrum requires arrays of metallic nanohelices in order to combine internal and Bragg resonances. However, their fabrication relies on costly electron/ion beam lithography or physical vapor deposition, in which it is difficult and time-consuming to control nanoscale morphology over large areas. New types of helix metamaterials and engineering processes based on self-assembly concepts are absolutely necessary in order to be viable for future technologies. Nevertheless, self-assembled metamaterials with large, broadband and tunable chiroptical responses in the UV-visible region is a great challenge due to the required subwavelength feature sizes. To this end, the helicoidal morphologies of chiral liquid crystals provide the ideal platform for maximizing chiral light-matter interactions. The objective of CELICOIDS is to investigate the use of the chiral liquid crystal phases of cellulose nanocrystals with end-tethered polyoxyethylene analogues as templates for the fabrication of a new class of metamaterial, solid metallic nanohelicoids. A recent breakthrough that now makes this project possible is the discovery that such cellulose nanocrystal hybrids form chiral liquid crystal phases. As one of the very few researchers in the world with the combined expertise in cellulose chemistry, polymer grafting and colloidal assembly, I am the ideal candidate to achieve success.