RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Wide Field Studies of Star Forming Regions' in the context of a Seventh Framework call.

assistant: **Objectives**

The UKIDSS survey and the upcoming VISTA surveys is/will produce unbiased wide field near-infrared observations that encompasses entire star forming regions. The same can be effectively combined with the Spitzer Space Telescope mid-infrared observations and the CO molecular line observations from the COMPLETE and millimeter continuum surveys from the SCUBA2 and HARP to conduct wide-field studies of star forming regions. Further, individual H2 line surveys and CO line surveys will reveal the outflows in these molecular clouds. We aim to combine this multi-wavelength  observations to investigate the structure, evolution and dynamics of young stellar population in molecular clouds and embedded clusters and study the initial mass function, feed back mechanisms from outflows and winds from massive stars. The results can be  used to test theoretical scenarios of star formation. The same datasets will also be used to address a second objective to investigate the formation of massive stars within these molecular clouds. The mechanism of the formation of massive stars and their early influence on the evolution of the star formation process within the molecular clouds, influencing the variables such as star formation efficiency in the context of queiscent and triggered star formation will be examined. The consortium members involved in the EU and third country(India) have individually and to some extent in collaboration pursued several aspects of the above research. The magnitude of available and to-be available data is enormous and efficient exploitation of these data for science investigation require multiple groups working on various aspects of the science. Through this proposal we aim to combine the expertise and efforts of three groups to obtain maximum output from the wide-
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Mobile Multimedia Systems' to be submitted under Fourth Framework.

assistant: **Abstract**

The main objective of the project MObile MUltimedia SYstems (MOMUSYS) is to develop and validate the technical elements necessary to provide audio-visual functionalities for mobile multimedia systems. Such functionalities are being identified in the context of ISO MPEG-4 which will become the standard for coding of audio-visual information in multimedia systems. Most of these functionalities are insufficiently supported by the available or emerging standards. In Particular, the main objectives are:To build a new Multimedia Communications System with full conversational possibilities, addressing all MPEG-4 functionalities;To have Field Trials with 20 - 60 Real Terminals and real users for symmetric and asymmetric Multimedia over wireless networks (8 kbit/s - 2 Mbit/s); a part of these trials will have global coverage;To be a platform for European work on MPEG-4.,Role in development of the MPEG-4 requirementsFirst MPEG-4 terminals, hardware and softwareFlexible source coding scheme for audio and videoContinuous development of the MPEG-4 Verification modelEfficient algorithms for SNHCMSDL proposalClear view about user needs with respect to future MPEG-4 servicesConnection of the MPEG- terminals to networks such as DECT, GSM and UMTSExpected ImpactThe trend to integrate compressed sound and video into multimedia systems requires new standards for storage and transmission of audio-visual data. Mobile Communications is a fast growing market, which will in future expand from mere voice services to integrated multimedia services. This requires the development of new technologies for the realisation of mobile multimedia terminals. The activities of MOMUSYS will be closely linked with the development of ISO MPEG-4. Thus MOMUSYS can be seen as a European initiative to push the dev
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Increasing complex I stability as a cure for mitochondrial diseases' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Mitochondria are found within every human cell and are responsible for the majority of energy production in the cell. When the mitochondria do not function properly, they cause devastating diseases affecting many and often multiple organs with the highest energy needs, such as skeletal muscle, brain, heart and liver. Over the years we have steadily increased our understanding of the genetic and molecular mechanisms leading to mitochondrial disease, developed different models and biomarkers. Unfortunately, development of effective therapeutic approaches able to improve the outcome of the diseases or at least to ameliorate or postpone the symptoms was much less effective.Today, therapeutic options for mitochondrial diseases still remain focused on supportive dietary interventions aimed at relieving complications. Therefore, it would be ideal if a single approach could be developed that would be equally effective with various mitochondrial diseases most often characterized by complex I deficiency.Our preliminary data show that by removing the major mitochondrial matrix protease CLPXP, and therefore stabilizing CI, we could ameliorate the symptoms of respiratory deficiency in different cellular models of mitochondrial dysfunction. The loss of CLPP in these models resulted not only in increased stability of CI, but also normalized NAD+/ NADH that collectively resulted in improved proliferation and survival rates. Remarkably, even partial loss of ClpXP activity in respiratory deficient cells led to mild increase in the CI levels, opening an exciting prospect for therapeutic interventions. Therefore, the overall goal of this project is to explore the possibility of targeting CLPP activity to ameliorate symptoms of mitochondrial diseases in in vivo models through genetic interv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Surface science research centre' to be submitted under Fourth Framework.

assistant: **Abstract**

Principal characteristics of the facility and of the support offered to users: A broad range of instrumentation is offered for fundamental, strategic and applied studies of surfaces, interfaces and surface processes covering metals, semiconductors and insulating materials. The complete understanding of solid surfaces and surface processes requires atomic/molecular scale knowledge of the physical structure of the surface, its elemental and chemical composition, electronic structure and the response of these characteristics to external influences of heat, gases, liquids, electromagnetic radiation and particle bombardment. The instrumentation, detailed in the proposal, although predominantly UHV based, also includes facilities for the study of liquid/solid and higher pressure gas/solid interfaces as well as shallow buried solid/solid interfaces. With Europe's highest spatial resolution scanning transmission electron microscope, solid state NMR and XRD facilities additionally being offered, there are 18 major instruments (including two end stations at the Daresbury SRS) which individually provide state-of-the-art surface science capabilities. It represents a unique collection of instrumentation which can be made available to European users as an integrated and highly co-ordinated package, managed under a single authority. A further eleven UHV support instruments (LEED, AES, XPS, TPD etc) are also available. Particularly attractive in addition to the STEM are the following instruments all of which have special and often unique characteristics: k-resolved inverse photoemission, variable temperature STM, UHV-scanning tunnelling microscope, reflection anisotropy spectroscopy, high resolution scanning Auger microscopy, high resolution electron energy loss spectroscopy and spot p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Chimeric Antigen Receptor to generate Alloantigen-specific Regulatory T cells and promote allograft tolerance'.

assistant: **Objectives**

Organ transplantation is the best life-supporting treatment for terminal organ failure. Graft survival is however limited by rejection, a destructive process resulting from the response of recipient’s immune system against donor specific alloantigens. Prevention of rejection currently relies on immunosuppressive drugs that lack antigen specificity and therefore increase the risk for infections and cancers. Induction of donor-specific tolerance would provide indefinite graft survival without morbidity and therefore represents the Grail of transplant immunologists. Tolerance has been obtained in experimental models with adoptive transfer of ex vivo-expanded CD4+FOXP3+ regulatory T cells (Treg). Preclinical studies have indicated that the potency and specificity of Treg therapy could be markedly enhanced by the use of Treg specific for donor alloantigens. Translation of this approach in the clinic has been hindered by the lack of clinically applicable strategies to generate sufficient numbers of potent donor-specific Tregs. To overcome this limitation, Pr Levings’ group (Child and Family Research Institute, Vancouver, Canada) has just recently successfully used chimeric antigen receptor (CAR) technology to redirect the specificity of human Treg toward a transplant-relevant antigen. The objective of the 2-year action is to assess the impact of alloantigen-specific CAR Treg on cellular and humoral alloimmune responses and their ability to promote allograft tolerance. The outgoing phase of the global fellowship will be performed in Pr Levings’ lab, and the return phase in Pr Glaichenhaus’ team (Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France) where the researcher will get in few years a tenured position. The main ambition of the program is to provide key
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'International Finance and the Great Powers, 1800-2020' (2021-2027), addressing dissemination and exploitation.

assistant: **Impact**

The world is entering a new era of great power rivalry, with the rise of China and the Russia-Ukraine war being only the most visible signs. This proposal asks: What are the implications of these developments for global finance? Will China’s rise accelerate financial globalization or rather reverse it? What do the growing tensions between great powers imply for financial markets around the world? And what motivates China to invest trillions of dollars of state funds into its Belt and Road Initiative (BRI)? It is difficult to answer these questions, because major shifts in the international order occur only every few generations. We therefore need to look back, but existing research in international finance mostly relies on evidence since the 1970s – from an era dominated by the US and in which states had limited influence on capital flows. As a result, our knowledge on the role of state power in global finance is limited. More generally, the literature on geopolitics and international economics is still in its infancy. With this proposal, I want to fill these gaps. I use theory, rigorous empirical methods, and comprehensive new data to study how the rise and fall of great powers (or geopolitics) shaped global investments over the past 200 years. In part one, I embark on a major data gathering effort on North-South capital flows and investor returns at a micro-level, covering tens of thousands of individual bonds, stocks, and infrastructure projects since 1800. In part two, I use this comprehensive new data to analyse: (1) how changes in the international balance of power influence the global allocation of capital; (2) how geopolitical shocks such as wars affect investor returns in the short and long run; and (3) whether and how rising powers use infrastructure investmen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Consolidating deep & inclusive social innovation ecosystems' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Consolid8 is paving the way for the integration of social innovation actors in innovation networks in 15 European ecosystems using the quadruple helix collaboration. From the challenges we identified in 5 pioneering ecosystems with different innovation performances (strong innovator – Ireland, moderate innovators – Italy, Greece, Slovenia, emerging innovator – Romania) we developed 5 capacity building programs that we will deliver to cater to the needs of 5 target groups from both the social innovation landscape, and the classic innovation ecosystems. We will harvest the lessons learned in delivering the different pioneering programs and we will exploit them in a follow-up European accelerator targeting additional 10 ecosystems which we will support through a validated methodology for accelerating ecosystems (developed and implemented by DEEP Ecosystems). We will link the 5 pioneering programs & showcase their results during a European social innovation festival in Brașov, Romania, that will aim to interlink social innovation actors with innovation ecosystems. We will ensure widespread visibility for this event at European level and we will launch an open call for the ecosystem builders to register for the accelerator for ecosystem builders. The project proposes strong pathways towards achieving impact, including activities aimed at developing 3 crowdfunding campaigns for social innovators, 1 research on an alternative financing program for social innovation for local authorities or researching and testing and showcasing 12 social innovation models with potential of scaling up and replicability. For the achievement of the project’s results, 8 partners across the quadruple helix are collaborating.


**Keywords:** social innovation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Functional analysis of the beta1d integrin in myogenesis' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

Integrins constitute a family of heterodimeric transmembrane glycoproteins involved in cell-substratum or cell-cell interactions. At least 16 alpha and 8 beta subunits have been identified, that may exhibit alternative splicing. Recently, a new muscle-specific splice variant of the B1 subunit has been identified, B1D. B1D is developmentally up-regulated during differentiation of myoblasts and is the most prominent B1 isoform in muscle tissue. Aim of this project is to specify the role of B1D in myogenesis and in muscular physiology. The main objectives include the study of the function of B1D in skeletal and cardiac muscle formation by gene targeting experiments as well as the assessment of its role in myoblast differentiation using an in vitro model. Insights into cell adhesion and integrin-mediated signal transduction will also be gained. Noteworthy, a novel gene targeting approach based on the Cre-loxP system will be used to generate splice variant specific knock-out mice.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Smart Power Management in Home and Health' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

According to studies, worldwide energy consumption is rising dramatically and will double in the next 20 years and with it CO2 emission. The consequence will be an escalating price for energy and upcoming challenges for ensuring Europe´s energy supply.Reducing Energy Consumption through energy savings can save up to 30% of Europe’s predicted energy consumption. Achieving efficient use of energy, without restricting the customer, is the political, social and technical challenge of the next decade.The high level objective of the SmartPM project is therefore to develop application-specific, efficiency-optimized semiconductor power technologies enabling actual deployment of intelligent systems in large-scale, energy-critical application fields like home and health. Applications in these fields require innovative system architectures and circuit designs, new components, efficient power electronic technologies, and innovative module, interconnect and assembly technologies. An important aspect is the support and the compatibility of upcoming legislation and regulations for efficient use of energy.The SmartPM consortium will develop semiconductor technologies and module platforms enabling (a) intelligent motor drives for highly efficient controlled engines in industrial and home applications, and (b) efficient power supplies and power management solutions that will to consume up to 25% less energy by 2012. The technologies under investigation follow the “More than Moore” path based on Si, SOI and SiC and cover different voltage ranges including low voltage (< 100V), net voltage (120V – 400V) and high voltage (>1000V).The implementation of the project results will save up to 25% of the electrical energy consumption and CO2 emission without losing performance, comfort or safety.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Sustainable Hydrothermal Manufacturing of Nanomaterials' under Seventh Framework.

assistant: **Concept**

It is vital that nanomanufacturing routes facilitate an increase in production whilst being 'green', sustainable, low cost and capable of producing high quality materials. Continuous hydrothermal synthesis is an enabling and underpinning technology that is ready to prove itself at industrial scale as a result of recent breakthroughs in reactor design which suggest that it could now be scaled over 100 tons per annum. Academic specialists with international reputations in reactor modelling and kinetics and metrology will develop the ‘know how’ needed to scale up the current pilot scale system. Selected project partners with expertise in sustainability modelling and life cycle assessment will quantify the environmental impact and benefits of a process that uses water as a recyclable solvent, whilst producing the highest quality, dispersed and formulated products. In addition to scale up production, the process will be improved through case studies with industrial end users in four key areas – printed electronics with SOVY; surface coatings with CRF, PPG and SOVY; healthcare and medical with ENDOR and CERA; hybrid polymers and materials with TopGaN and REPSOL. Further value will be added to the Project by working on new materials that have been identified as key future targets but cannot be currently made, or made in significant quantities. The consortium is founded on the principle that the whole value chain (from nanoparticle production to final product) must be involved in the development of the technology. This will not only inform the development stages of the production process but also maximise ‘market pull’, rather than simply relying on subsequent ‘technology push’.