RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Managing donkey and horse resources following the collapse of the Roman Empire in France' (PostEquus) under Horizon Europe.

assistant: **Objectives**

Alongside horses, donkeys represent a member of the horse family, well-known for their economic, social and ritual importance in proto-historic France. Traditionally, horses and donkeys have provided humankind with complementary services, not only enhancing our capacity to travel well above our own speed, but also to transport heavy loads across rugged landscapes and to improve farming yields. However, the entire history of horse and donkey management remains difficult to reconstruct based on textual, iconographic and archaeological evidence. The sequence of ancient DNA molecules preserved in archaeological remains has recently provided a new, complementary historical source, considerably advancing our capacity to track the numbers, types and movements of domestic animals in the past, and therefore, to unravel changing herding management practices through time. PostEquus will apply state-of-the-art approaches in ancient horse genomics and develop an innovative genotyping solution for the domestic donkey, to generate an unprecedented corpus of genomic data to assess the phenotypic and genetic diversity of both species in the past history of France. By genetically profiling horses and donkeys from the collapse of the Roman Empire (6th century CE to the 18th century CE), PostEquus will reveal the whole breadth of equine management strategies and their evolution in the face of major societal crises and invasions.


**Keywords:** France, ancient DNA, horse, donkey, Middle Age
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Radiative transfer effects on air pollution dispersion in urban areas: from the street scale to the neighbourhood scale', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

This project aims at understanding the effects of radiative transfer on air pollution dispersion in urban areas at both the street scale and the neighbourhood scale. Numerical models will be developed, for that purpose, that will help design and manage our cities, buildings and traffic systems in order to produce sustainable, safer, healthier, and more comfortable urban environments.Radiation modelling will be coupled with 3D fluid dynamics, urban geometry, particle and pollutant transport, traffic and environmental conditions to produce the first model able to take into account radiation transport effects at both street and neighbourhood scales. Benchmark numerical simulations at the street scale will provide detailed information on radiative transfer effects subject to various environmental conditions: presence of clouds, humidity, turbulence level, etc. These results will help to derive simple physically relevant models for the simulations at the, much more computationally expensive, neighbourhood scale. The intensive use of fully adaptive methods for both radiation and fluid dynamics will also contribute to make feasible the simulations at this scale.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Data Integration System for MARine pollution and water quality' in the context of a Fifth Framework call.

assistant: **Objectives**

Marine monitoring of water quality and pollution is carried out in many different ways around Europe, using either aircraft or ship based observations, satellite data, in situ measurements from automatic buoys or Ferry Box systems, or by various combinations of these methods. Forecasting of physical parameters is carried out more or less operationally, whereas modelling of bio-chemical processes is more on the research level. Coupled physical-biochemical models and oil drift models are in some cases used in semi-operational mode. Previous projects have addressed specific observing methods or information system, which facilitate access to data. Little effort has been put into combining monitoring and forecasting of marine pollution and water quality in one system, and to develop end-to-end service chains, which can operate across national borders. This is the aim of DISMAR.Objectives:Develop an intelligent system for monitoring and forecasting of the marine environment to improve management of natural or man-induced pollution crises in coastal and ocean regions of Europe, supporting public administrations and emergency services responsible for prevention, mitigation and recovery of crisis such as oil spill pollution and harmful algae bloom. A prototype will be built for integration of multi-source data and numerical models for use in forecasting and risk assessment. The capability of a prototype will be tested and evaluated by regional applications. The benefit of using satellite data in synergy with other observing systems will be demonstrated in the context of GMES.Work description:The main challenge of DISMAR is to develop a system which can1) provide access to a wide range of data types relevant for the marine environment, both archived and near-real time data;2) com
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Artificial Mitochondria for Health' in the context of a Seventh Framework call.

assistant: **Objectives**

Mitochondria are cell organelles that provide the energetic requirements of the body. The majority of cellular ATP is produced by the membrane protein ATP synthase through a proton gradient across the mitochondrial inner membrane. Alterations in ATP synthase biogenesis can result in severe mitochondrial diseases affecting tissues with high energy requirements as brain and muscles. Mitochondrial diseases affect approximately 20 million people in the EU, causing 35 % of deaths during the first year of life of newborns. However, the available therapeutic approaches, are still extremely limited and there is no specific treatment for ATP synthase deficiencies. To improve the treatments currently available for mitochondrial diseases, the project will focus on the realization of artificial mitochondria (AM). Based on artificial lipid vesicles, AM will be fabricated by means of microfluidics methods, a powerful tool able to produce identical replicas of a given bio-inspired membrane-object. ATP synthase will be expressed and assembled within the lipid bilayer by encapsulating cell-free protein expression systems. To test the ability of AM as in-situ energy fabrication systems, targeting-AM will be endocytosed inside cultured cells and ATP synthesis will be triggered by taking advantage of the proton gradient provided by endosomes. Finally, by enclosing other plasmids encoding for diverse proteins, AM can be used as energy-factoring pockets to elicit protein expression just when internalized within cells. This novel approach may constitute an advanced new concept in gene therapy to more effectively create breakthroughs in improving human health.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'ANtibioticS and mobile resistance elements in WastEwater Reuse applications: risks and innovative solutions' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

In response to the increasing problem of water shortage, the reuse of treated urban wastewater is considered the most suitable and reliable alternative for sustainable water management and agricultural development. In spite of the benefits associated with this practice, major concerns currently exist, related to the adverse effects regarding chemical and biological contaminants of emerging concern such as antibiotics and mobile antibiotic resistance elements such as antibiotic resistant bacteria and resistance genes. These are now considered as a serious public health problem by various international organizations and the European Commission, because of their spread in the environment, the food chain, drinking water, etc. To tackle these problems, scientists with an interdisciplinary research/training background are urgently needed. This ETN will train a new generation of ESRs to address the risks associated with such contaminants and wastewater reuse. Innovative chemical, microbiological, toxicological and modelling tools, and novel process engineering will form the scientific and training core of their innovative research projects and training. The project will contribute to understanding the fate and transmission of antibiotics and resistance from wastewater to the environment and humans, through soil, ground/surface water and crops. Relevant ELVs will be determined, essential for the development and implementation of regulatory frameworks. This project directly tackles these aspects, by bringing together a multidisciplinary research team, with the private sector, and policy makers and through communication activities towards stakeholders and the wider public.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Genetic and environmental risk factors for common malignant tumours especially breast cancer and melanoma' (2007-2013).

assistant: **Concept**

A prerequisite for prevention or early diagnosis of  a tumour disease is that environmental and/or genetic risk factors are characterized in order to better define risk groups. The present research proposal focus on common malignant tumours, especially breast cancer and malignant melanoma . By combining risk factor studies on endogenous and exogenous environmental, and genetic risk factors and its interaction, the aim is to better characterize  strong determinants of risk. The project also aims at better understanding the mechanisms of disease and for different exposures, such as sun exposure and different hormonal exposures, obtain a global assessment of possible positive and negative health and disease effects. The infrastructure includes large population based cohort and case-control studies, pathological and clinical patient information, biobanks from cancer patients and controls, availability of excellent genomic resources and an extensive network of national and international collaborations. Very often it has been possible to work out from a population based perspective. Both for breast cancer and melanoma the research group has identified important genes or modifiers of dominant predisposing genes as well as environmental or constitutional risk factors. Through an extensive international collaboration gene and gene-environemnt interaction studies are undertaken. The ulitmate goal for the new knowledge is to prevent or early diagnose the malignancy. In hereditary cancer and for some of the hormonal exposures successful results already are seen. The applicant has been involved more than 30 years in epidemiological research  of cancer,  and published more than  400 publications  in international journals and fostered a large number of PhD students.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Linguistic Texts of Roman Antiquity. Collecting fragments, sources and lexicon in a digital environment' (LiTeRA).

assistant: **Innovation**

All modern histories of Western linguistics start with its Greek origins (5th - 3rd cent. BC) and then, after mentioning the Latin Republican polymath Varro (1st cent. BC), jump several centuries to explore only some prominent, late figures (4th - 6th cent. AD). The aim of the LiTeRA project is to provide a holistic perspective on the birth and configuration of Roman linguistic science (2nd cent. BC - 3rd cent. AD), an essential moment in the evolution of Western culture. Although we have inherited valuable sources from the late Latin grammatical tradition, this project will shed light on the overlooked works of the preceding Republican and early imperial periods, a vast body of texts, which have not survived in their entirety, but have been excerpted and quoted in late normative handbooks, commentaries, and lexica. LiTeRA’s three interrelated objectives illuminate how the history of ancient Roman linguistic thought can be substantially rewritten by mobilizing:- A heuristic step: to collect all of the foundational fragmentary texts of Latin grammar, written by a hundred authors and transmitted in the source-texts of late antiquity;- A hermeneutic step: to contextualize the interpretation of the lost texts, extending the sources of Latin grammar to the wider context of ancient Roman scholarship;- A historical step: to reconstruct the evolution of Latin grammatical terminology from its historical roots in the reference corpus of source-texts to its modern conceptualization.LiTeRA’s unique approach to decipher the internal correlations between these related corpora, which are not at all mutually exclusive, will necessitate new methodologies that consider their textual polyphony and intricate technical vocabulary. LiTeRA demonstrates that examining these interconnected issu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Circulating Tumor Cells TheRapeutic APheresis: a novel biotechnology enabling personalized therapy for all cancer patients' (CTCTRAP).

assistant: **Innovation**

Chemotherapy is slowly being supplemented by a new generation of drugs that recognize specific targets in or on cancer cells and has proven to be more effective with markedly fewer side effects. During the course of the disease alternative oncogenic signaling pathways take over inevitably leading to drug resistance. As a consequence renewed tumor analysis is required to redefine the optimal treatment regiment. However a biopsy can frequently not be obtained without risk and or discomfort to the patient.  Circulating tumor cells (CTC) may circumvent this problem.CTC refer to cells that detach from a primary tumor or metastatic site, circulate in the peripheral blood and may form metastasis. CTC represent a ""liquid biopsy"" that can be used to tailor treatment for individual patients. CTC are however rare and can only be obtained for further characterization in a small fraction of patients.In the CTCtrap consortium universities, research institutions and SMEs are linked in a common effort, starting from the simple, but innovative view of using Therapeutic Apheresis (TA), as a way to collect CTC from peripheral blood in cancer patients.A new TA column will be developed to capture CTC and then reintroduce the blood devoid of tumor cells back into the body with the promise to obtain CTC in all patients at risk for recurrence or diagnosed with metastatic disease. The molecular characterization of these CTC is expected to gather new knowledge on metastasis' mechanism, provide a risk assessment and the optimal therapy choice during the course of the disease of cancer patients. The new knowledge on CTC heterogeneity within cancer type and within individuals will allow for the tuning of CTCapheresis to specific cancer types. Prospective pilot studies will be setup to investigate
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Quantum states in ultracold fermionic gases in optical lattices:Supersolid and dynamic antiferromagnetic states' (SUPERSOLDYNAF).

assistant: **Innovation**

In recent years the fields of condensed matter physics and ultracold atomicgas physics have developed a fruitful interplay. The former has a long historyof describing quantum states of matter based on simplified models,such as the Hubbard model, whilst the latter now manages tosimulate these models and generate exciting quantum states. Thetwofold objective of the research project is to betterunderstand the stability of the supersolid quantum state and thenon-adiabatic dynamic generation of antiferromagnetic (AF) quantumstates. The supersolid state of matter, a peculiar state withsimultaneous crystalline order and superfluid properties, hasbeen proposed to be realizable in a gas of attractive fermionsconfined to an optical lattice. The research project willtheoretically model such a state and analyze its stability. This will beachieved by real space dynamical mean field calculations utilizing thenumerical renormalization group as an impurity solver.The second part deals with a correlated fermionic system whichby an interaction quench is driven into a situation where a strong AFinstability is present. Using the Hubbardmodel, we will develop and apply non-equilibriumtechniques to understand the resulting behavior.A realization of this non-equilibrium situation is possible foran ultracold gas of fermions in an optical lattice with commensuratefilling, which is tuned suddenly to the stronglyrepulsive side of a Feshbach resonance. There, the AF instabilitycompetes with processes of molecule formation, whichcan also occur on this side of the Feshbach resonance. By taking intoaccount both processes we will investigate theoretically thetime-dependent response of the system and predict itsdominant behavior.Current experiments are performed in regimes very close to the situationsd
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Non-commutative geometry of quantum homogeneous spaces' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

In global analysis or in algebraic geometry, a geometric space is described by an algebra of functions on this space. Non-commutative geometry extends this approach to geometry also to non-commutative algebras. In this way, A. Connes generalized in particular results from index theory and spin geometry. The aim of this project is to apply the methods of non-commutative geometry to so-called quantum homogeneous spaces. There are several definitions of this notion, but all of them cover a class of algebras that are obtained by quantizing the irreducible generalized flag manifolds (the irreducible compact Hermitian symmetric spaces) with respect to some Poisson bracket. For these, the proposer constructed a Dirac operator fitting into Connes and apos; concept o f a spectral triple (a non-commutative analogue of spin manifolds). Now, the main objective is to investigate quantum homogeneous spaces focusing on homological aspects.The goal is also to extend the aforementioned construction of Dirac operators for quantum flag manifolds to a larger class of quantum homogeneous spaces, and to study the algebraic properties of analogues of Clifford algebras that were involved in obtaining these Dirac operators. One of the motivations of non-commutative geometry is to make assertions about physical models in the non-commutative setting. A long-term objective of this project is to formulate and study Yang-Mills theory on quantum homogeneous spaces. P.M. Hajac, the researcher in charge at the host institution (IMPAN), has worked on such topics for about a decade and made some significant contributions to the subject. There are several groups at IMPAN and the University of Warsaw that work on related topics. Finally, the planned Transfer of Knowledge grant and quot; Non-commutative Geo