RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Attention Warps Early Sensory Maps' (AWESOME) under Seventh Framework.

assistant: **Objectives**

Localizing objects in physical space requires integrating information about head position, eye position and location of stimulation on the retina. The first cortical stages of visual processing contain retinotopic maps that maintain the relative locations of retinal stimulation along the surface of the cortex, providing an obvious basis for space perception. While it has been long assumed that these maps are fixed and determined by the anatomy of the retino-cortical projection, recent neuroimaging and electrophysiological studies have challenged this view by suggesting that contextual effects such as depth information and attention can distort these maps.We propose to use a combination of behavioral and neuroimaging techniques to investigate the neural substrates of space perception. Brief flashes presented during shifts of attention or gaze direction are known to be systematically mislocalized. Using fMRI and Multi-Voxel Pattern analysis, we will locate the representation of these stimuli within retinotopic maps to determine if it corresponds to the real or the perceived location of the stimuli. In this way, we will quantify the effects that attention and eye movements induce on the neural representations of visual space, and how do they correspond to the distortions of visual perception. We will test the novel hypothesis that the pattern of neural activation reflects the perceived stimulus position since the earliest stages of visual processing, with visual maps adapting flexibly and dynamically in response to the behavioral demands.The proposal involves two of the best international laboratories for the study of the human vision, attention and eye movements, and makes use of the most advanced neuroimaging tools and analysis techniques. The skills that will be acquire
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Novel inhibitors of adhesin/receptor interactions involved in microbial infection at mucosal surfaces (ADRI)' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

This proposal, involving critical network European scientists, is to investigate a novs approach to the prevention of microbial infection at mussel surfaces, namely, mussel application of molecules that specifically inhibit the attachment of pathogenic microbes. In view of considerable concern over the spread of antibiotic resistance, such an approach is timely. Molecules to be used, as specific inhibitors will be analogues of either the microbial adhesion or the host receptor, antibodies and antibody fragments. We have chosen a viral, a bacterial and a fungal mussel pathogen for each of which adhesions receptors have been well defined and for which there are established relevant animal models. These models will allow in vivo testing of inhibitors, and their modes of delivery, and of compounds witch can boost innate immune clearance mechanisms. The proposal should lead to the development of navel antimicrobials for the prevention and control of human infections and establish a rationale for the development of further antimicrobials.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Smad4-Ubiquitination by opposing E3 and DUB activities: a central control element in TGF-beta signaling'.

assistant: **Innovation**

The research here outlined deals with the relevance of ubiquitination in TGF-beta growth factor signalling. As outlined below (subchapters) TGF-beta signalling is fundamental for embryonic development and for a variety of human pathologies. In particular, recent data showed that tuning TGF-beta signalling is essential for differentiation of pluripotent cells and for cancer and metastasis. The proposal is therefore highly relevant not only scientifically but also for the socio-economic reasons. We will place emphasis of monoubiquitination as a mechanism to regulate protein function, which is a new concept emerging in signal transduction. Multidisiplinarity. As TGF-beta is such a pleiotropic cytokine, the research is highly multidisciplinary, ranging from biochemistry of the Smad4 signal transducer, to identification of new enzymes impinging on Smad4 ubiquitination levels, and how these events ultimately impact on the embryonic development and proliferative behaviour of adult cells. The reason for me to apply to this incoming international fellowship is to linked my specific expertise, that is, the ability to carry out special type of manipulations such as depletion of maternal mRNA in Xenopus oocytes (that are simply not present in Europe) or generation of transgenic frogs (poorly diffused). These technologies will be of help to the characterization of the embryonic phenotype of Smad4 modifying enzymes that are supplied maternally to the conceptus. Being the hosting laboratory a world leader in the TGF-beta signalling and embryonic development field, these expertise will now be able to spread in Europe. My own expertise will therefore integrate with those of the hosting group leading to a mutually beneficial and synergistic approach to a very complex and daring biologica
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Access to I4MS' (XS2I4MS), addressing dissemination and exploitation.

assistant: **Impact**

The new industrial revolution which is  based on the deep integration of ICT in manufacturing and characterised by new industrial technologies such as cyber-physical systems, IoT, additive manufacturing, and simulation offers great potential. EU industries are well placed to benefit from the new ICT- driven industry, but a challenge is for SMEs to participate in and to benefit from the new industrial revolution. To turn this vision into reality for European SMEs the I4MS project aims to increase the uptake of ICT by manufacturing  SMEs. It does so through innovation and support actions. The Access to I4MS (XS2I4MS) project is  a support action to advance the European I4MS community, and expand its coverage, notably through the I4MS Mentoring programme which is aimed at supporting the establishment of a network of Digital Innovation Hubs. XS2I4MS supports the continued expansion of services provided to DIHs in a number of ways. It has established a special section on the single portal for the I4MS community (WP1). The project builds a solid information base for I4MS in WP2 - the I4MS Observatory. Sharing best practices and dissemination (WP3) aims to extend the reach and impact of IMS as widely as possible through the collection of information about other digitization activities in Europe. Brokerage support and information activities (WP4) are aimed at supporting a key task of the DIH and also focuses on the assessment how DIHs can be financed. Specifically, the outreach activities in WP5 (Mentoring and Coaching for Regional Innovation Hubs) aim to extend the network to include SMEs in regions not currently participating in I4MS. WP6 (Management and Coordination) will ensure effective coordination of tasks.The XS2I4MS consortium presents a strong mix of organisations to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Harnessing the innate and adaptive immune system with targeted neoantigen based cancer vaccines' (SPLITVAC), addressing dissemination and exploitation.

assistant: **Impact**

Immunotherapy for cancer has recently shown great clinical potential. However, only small percentages of patients do benefit from these therapies. The dual objective of the proposal is to understand and harness the immune system in vivo to develop truly personalized (individualized) anti-cancer treatments and to develop powerful bioconjugation technologies to generate new and better biotherapeutics. The project objectives will be achieved through the combination of ProteoDesign’s site-specific bioconjugation technology, with recent advances in the field of immuno-oncology, particularly the importance of tumor specific mutations (neoantigens), as drivers of anti-tumor immunity. The therapeutic candidates that will be obtained as a result of the project are personalized and have the potential to treat cancer at the individual level. These therapies are based on the mutational landscape of any given tumor, and so they could be applied to multiple cancer indications. The proposal will face specific challenges regarding the development of complex personalized bio therapeutics.The project will be carried out through the collaboration of Dr. Vanhooren and Barcelona based biotech ProteoDesign. Dr. Vanhooren has extensive know-how and experience in the pre-clinical development of biologic-based drugs, and ProteoDesign has a proprietary technology for the discovery and development of new therapeutic bioconjugates. Through the present proposal bidirectional knowledge transfer will take place between the fellow and the host, thus enhancing know-how and skills on both sides. Dr. Vanhooren will be focused on leading the project, setting and adapting objectives, designing experiments, supervising the team and analyzing results. During the project and through a specific plan, ProteoDes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Citizens' observatory for coast and ocean optical monitoring' in the context of a Seventh Framework call.

assistant: **Objectives**

In the marine environment, anthropogenic pressures on resources and non-anthropogenic causes may create harmful conditions that affect human society. Harmful algal blooms and habitat destruction are examples, which pose serious human-health threats and severely affect numerous industries, causing annual economic losses in the tens of millions of euros, in the form of reduced sales, diminished tourist activity and unemployment. A widely adopted, scientific way to assess the environmental status of water bodies is by measuring their optical properties (as indicators of, e.g., sewage impact, dissolved organic matter, sediment load or gross biological activity). The Citclops project aims to develop systems to retrieve and use data on seawater colour, transparency and fluorescence, using low-cost sensors combined with contextual information (e.g., georeferencing) and a community-based Internet platform, taking into account existing experiences (e.g., Secchi Dip-In, Coastwatch Europe and Oil Reporter). Simple and fast methods to establish the optical properties of seawater will be developed and used: e.g., the colour through Forel-Ule observations, and transparency through a variant of the Secchi disc. People will be able to acquire data taking photographs of the sea surface on ferries or other vessels, at the open sea or from the beach. Wearable digital cameras for aquatic activities with extended sensing systems are also proposed as alternative resources for crowdsourcing data. Data are automatically uploaded through a specific service or application (such as Google+ Instant Upload), archived remotely and processed, and resulting information is accessed through a webpage or a mobile application by end users. These are: policy makers (e.g., local administrations), which will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'A competitive concept for the paper industry towards zero liquid effluent' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

As economic circumstances change and environmental legislation tightens, paper mills are forced to minimise their energy and water consumption and produce minimum emissions. Without the introduction of new technologies and chemicals, increased re use of the process water will lead to a whole range of production and process problems and a reduction of product quality. To enable a further closure of the water loop, all `accumulates' should be controlled and/or prevented. In that aspect, pulp and paper mills need to introduce new low cost technologies and chemicals to achieve a cleaner process in combination with reduced production costs, which results in a better energy efficiency, reduction of water demand and reduction of emissions. Objectives of this project are: * Industrial: Reduction of water (50%), energy (35°/) and chemical consumption (35%) combined with an improvement of the paper machine runnability and an upgrading of the product quality bv applying clean technologies. * Economical: - Reduction of production costs of paper by 10 ECU/ton (300 1.150 kECU/vear for average participating mills) - Increase of the competitiveness of the European paper mills. - Increase market share for the technology suppliers in the paper and process industries like textile and food * Social: - Implementation of environmental clean technologies to reduce environmental pollution and human risks. - A more sustainable paper production in terms of reduced energy and water consumption. - E;xploitation of the results to give similar savings at other paper mills and other process industries. - Education of the technical employees in the paper mills. The research approach will be applied scientific research, which means that successful results will be implemented into the paper mills. The o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Science, technology and governance in europe' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The public response to scientific and technological innovation is increasingly seen as central to both economic and social policy. Key issues of the relationship between public accountability and effective strategy, which are confronting governments at all levels, have broad significance for the future of governance in Europe. STAGE will build on and synthesise earlier work under FP4, current research, and case studies in three contrasting technology domains, in order to construct, test and disseminate to users and beneficiaries a conceptual model of:- how policy cultures - local, national and European - construct and process the S&T agenda; - the range of social actors involved and the scope of their participation; - the relation of issues, processes and participants to outcomes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'A disruptive method to free physicians from Hospital Information Systems by generating fault free patient diagnostic documents in real-time using natural language' (REALM) under Horizon 2020.

assistant: **Objectives**

A significant bottleneck in Europe’s health care model is that physicians are spending up to 30 % of their time operating complex Hospital Information Systems (HIS). The Diktamen-method totally frees the physician from HIS and revolutionizes any voice-to-text capabilities. All diagnostic data is expressed with natural language, while the error free diagnostic document is produced in real-time. Our pilot study showed that physicians treat 25 % + more patients per day with the Diktamen-method. According to our growth plan this is the equivalent of generating 13 888 new physicians inside EU-27 by the year 2020.


**Keywords:** Diagnostic, Patient, Disruptive, Hospital Inofrmation System
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The Social Anthropology of Rabies Epidemiology and Elimination' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Rabies is a viral disease transmitted to humans through the bite of rabid animals, predominantly domestic dogs. It is ranked among the highest priority zoonotic neglected diseases by major international human and animal health organizations (the World Health Organization and World Organisation for Animal Health) and its control is considered a global public good. Although rabies is preventable through administration of post-exposure prohylaxis to individuals exposed to suspect rabid bites and mass vaccination of dogs, the disease still kills thousands globally. India has the highest number of rabies deaths in the world for reasons that are likely to be as much socio-cultural as they are biological, although these factors have neither been investigated nor integrated with epidemiological data. In India, I will focus on two contrasting (based on linguistic,cultural and religious background) rural areas of Gujarat and Maharashtra, where rabies is very prevalent. I will first investigate cultural and religious aspects shaping attitudes towards dogs and local-level acceptance of rabies control and prevention measures, including dog vaccination and human rabies prevention. I will subsequently explore the feasibility andacceptability of in-depth epidemiological data collection tools, contact tracing, to understand cultural and religious influences on people’s health seeking behaviour, practices that may lead to increased rabies risks, and management of these risks within this particular socio-cultural context. Data gathered in this preparatory phase will ultimately inform the design ofculturally acceptable and integrated One Health interventions that will to contribute to reduced rabies exposures and mortality. Together with these expected health benefits, my project will demo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'MIcrobiota-Gut-BraiN EngineeRed platform to eVAluate intestinal microflora impact on brain functionality' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

What is the relation between the intestinal microflora and the brain in the development of neurodegenerative disorders like Alzheimer's and Parkinson's disease? A functional relation between the intestinal microflora (microbiota) and the brain, referred to as the “microbiota-gut-brain axis”, was hypothesized more than 100 years ago but only recently has been re-evaluated becoming a new, exciting hypothesis in neuroscience. We have the proof that aging, bad alimentary habits, poor food quality and stress can affect our intestinal microbiota: the impact of this modification on brain functionality has been observed but the absence of suitable research tools does not allow verifying this research hypothesis. My aim is to overcome this limitation through a bioengineering approach: I will develop the first microbiota-gut-brain platform relying on three miniaturized microfluidic compartments, representing in vitro the most important features of microbiota-brain interaction. Once validated, my platform will be challenged in healthy and neurodegenerative scenarios by using human complete microbiota. MINERVA has a ground breaking potential: the proof of a causal link between intestinal microbiota and brain functionality would completely change the actual scenario, shifting the investigation of neurodegenerative disorders causes from the brain to the body periphery. MINERVA is a high gain project: if its vision succeeds, neurodegenerative disorders will benefit from new, cost effective, low invasive preventative and therapeutic strategies based on microbiota management by food ingredient and probiotics with an enormous beneficial impact worldwide. MINERVA will provide a versatile platform that will overcome the strong limitations arising from the current in vivo models and standar