RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Directions in Religious Pluralism in Europe: Examining Grassroots Mobilisations in Europe in the Shadow of European Court of Human Rights Religious Freedom Jurisprudence' to be submitted under Seventh Framework.

assistant: **Abstract**

The European public square has, in the last twenty years and increasingly so, been inundated with controversies around the place of religion in the public sphere. Issues such as freedom of religious expression, freedom of speech v. blasphemy, and the public display of religious symbols loom large in the workplace, in schools, in media coverage etc., at the local, national, and supranational level. The presence of Islam has been a catalyst for many debates on religion in Europe, but these have now grown to encompass much broader assumptions about the nature of religious communities, their relationship to state institutions, and the place of minority religious communities in society. Against this backdrop the European Court of Human Rights (ECtHR) adds its own voice and significantly influences the terms of the debates. This project examines the domestic impact of the ECtHR religion case law: it explores the mobilisation of local and national level actors in the wake of a number of high-profile ECtHR religious freedom cases in order to determine the nature and extent of European juridical influence on religious pluralism. In light of scholarly debates questioning the direct effects of courts, the project probes developments that take place ‘in the shadow’ of the Court. It engages especially with the extent to which court decisions define the ‘political opportunity structures’ and the discursive frameworks within which citizens act. What is the aftermath of the Court’s religion jurisprudence in terms of its applications at the grassroots level? The question is important because ECtHR case law will shape, to a large extent, both local and national level case law and – less conspicuously but no less importantly – grassroots developments in the promotion of or resistance to r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Trento2001-02' (1998-2002).

assistant: **Innovation**

Proposed Events:Euro Summer Schools TRENTO2001-02 PROPOSER. EAGER, a European Network in Algebraic Geometry, sponsored by the EC Human Potential Programme (contract HPRN-CT-2000-00099). Keynote Speakers:L. Caporaso (IT), J. Harris (USA),I. Morrison (USA) in 2001, H. Clemens (USA) and C. Voisin (FR) in 2002 Project Topic: Algebraic geometry is a core mathematical discipline that has been intensively studied since the late 19th century. It provides a range of geometric techniques describing solutions to equations. Because most of mathematics is concerned at some level with setting up and solving equations, for example to model problems in applications, algebraic geometry plays a central role in mathematics and physics.The planned schools address particularly themes with close connections to physics (string theory) and arithmetic: the invited keynote speakers will lecture on Moduli Spaces of Curves in 2001, and on Algebraic Cycles and Hodge Theory in 2002. Programme Content: The TRENTO schools are designed for effective, advanced training of post-docs in algebraic geometry and related fields. Each event brings 40 European post-docs and 20 further participants together with a few selected international experts as keynote speakers. In the mornings, the invited experts give mini-courses on the chosen topics, with lectures and problem sessions. Selected junior participants give seminar lectures in the late afternoons. Each junior talk is followed by a discussion with particular emphasis on constructive comments by the keynote speakers. The early afternoons and the evenings are reserved for junior-to-junior, junior-to-senior, and senior-to-senior discussions, with office hours" scheduled by the invited speakers."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Digital twins for model-driven non-invasive electrical brain stimulation' (Neurotwin).

assistant: **Concept**

Neuropsychiatric disorders are a leading cause of global disability-adjusted life years, and solutions are lacking.  Can digital twins be useful? At least in some cases, we hold they will be central to progress. Recent findings suggest that non-invasive brain stimulation may be a valuable option in conditions such as epilepsy or Alzheimer's (AD). Still, a better understanding of mechanisms and patient-specific factors is needed. Personalized hybrid brain models uniting the physics of electromagnetism with physiology – neurotwins or NeTs – are poised to play a fundamental role in understanding and optimizing the effects of stimulation at the individual level.  We ambition to deliver disruptive solutions through model-driven, individualized therapy. We will build a computational framework – weaved and validated across scales and levels of detail– to represent the mechanisms of interaction of electric fields with brain networks and assimilate neuroimaging data. This will allow us to characterize the dynamical landscape of the individual brain and define strategies to restore healthy dynamics. Benefitting from existing databases of healthy and AD individuals, we will deliver the first human and rodent NeTs predicting the effects of stimulation on dynamics. We will then collect detailed multimodal measurements in mice and humans to improve the predictive power of local and whole-brain models under the effects of electrical stimulation, and translate these findings into a technology pipeline for the design of new personalized neuromodulation protocols which we will test in a cohort of AD patients and healthy controls in randomized double-blinded studies.  With research at the intersecting frontier of nonlinear dynamics, network theory, biophysics, engineering, neuroscience, c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Radiation quantities, units and measurement' (1998-2002) under Fifth Framework.

assistant: **Objectives**

The network will develop comprehensive reports relevant to the areas of quantities and units, basic data, radiation protection and ecology and medical applications.These will cover such subjects as retrospective assessment of exposure, operational quantities for neutrons, chest radiography, electron beamtherapy, dose specification in nuclear medicine, beta-ray and photon dosimetry for therapy, dosimetric procedures in diagnostic radiology, nuclear data for neutron and proton therapy and radiation protection,dosimetry of high-energy photon beams, stopping powers for heavy ions, quantities and units for radioecology and requirements for radioecological sampling.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Exploitation of an improved vertex detector in the aleph experiment'.

assistant: **Innovation**

The applicant wants to work in the commissioning, operation and physics analysis of a new double-sided vertex detector, to be installed at the beginning of 1996 in the ALEPH experiment at LEP. The vertex detector is used to identify charged particles coming from the decay of unstable particles, such as b-flavoured hadrons. The use of the new detector will enhance the detection efficiency for b-quarks by about 20%. The advantages of the new vertex detector are most important during the second phase of LEP experiments, in the search for the Higgs boson. The research project is aimed to optimize reconstruction algorithms for the most common final states originating from the Higgs boson production and decay.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Advanced Receiver Terminal – eXtension to technology and market evolution' to be submitted under Seventh Framework.

assistant: **Abstract**

In the frame of ART-X, a professional receiver shall be prototyped, based on the experience form the previous ARTUS FP6 project, but improved towards a commercial competitive receiver in terms of functionality, performance, cost, size and power taking into account the evolving satellite navigation systems, changing markets and user needs. The objective is to have a full flexible, but yet powerful receiver being able to process all Galileo, GPS and GLONASS L1 signals, also for heading/attitude applications on one board (including RF-front-end, signal conditioning and processing and RTK navigation in real-time). The latest developments in advanced technologies (multi-frequency RF-Front-Ends, software receiver) shall be fully taken into account. Also considerable improvement of algorithms for real-time detection and mitigation of the three main measurement errors (multipath, interference and scintillation) being observed today in reference stations is a core topic. It shall also upgrade the AIV signal generator tool from ARTUS with multiple RF-signals for heading(attitude) capability. Functionality and performance validation shall be based on the laboratory signal generator, the GATE test environment and the Galileo GIOVE/IOV signal on E1, E5, E6, but also the GPS L1, L2C and L5 signals and the GLONASS L1 signal. Emphasize will also be put on evaluation on the competitors IP context being a precondition for successful commercialization. But also the setup of convincing product roadmaps to meet the user market demands will be a major focus.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'MULTIVALENT NUTZBARE UND MODULAR STRUKTURIETE EXPERIMENTALANLAGEN' (MULTEX) under Fourth Framework.

assistant: **Objectives**

The use of synchrotron radiation (SR) technology as a production tool for microsystem technology and materials research is presently limited to specifically constructed experimental accelerator facilities. The large number of individual beamline solutions developed for specific applications at sources like DESY, BESSY or the ESRF impede the broader use of synchrotron radiation for applications in micro-manufacturing and analytical processes and as a result slows growth in microsystem technology. Important elements of synchroton stations are outlet systems (such as dipole vacuum chambers) and beamlines for the extraction of particular beams form the accelerator. These components form the necessary link between radiation source and experiment and are manufactured specifically for each experiment. The manufacture of many of these components for SR facilities is increasingly being carried out by SMEs, thus introducing new high-technology engineering skills to the market. In the MULTEX project a modular system with well-defined interfaces for multivalent application in experimental stations of different radiation sources is to be created for broader and more effective use of synchrotron radiation. Based on an analysis of existing solutions, design elements should be systematised and a minimum of necessary modules for experimental stations identified. For these modules standardised interfaces are defined and applied in design and manufacturing stages. After manufacturing of appropriate prototypes the applicability in a synchroton station has to be proved and finally, requirements of redesign realised. Application of these modules leads to advantages of competition within the EU due to shorter development times (expected to be reduced by about 35-40%). Feasible stock-keeping o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Cancer Immunology and Immunotherapy' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Our objective is to develop therapeutic anti-cancer vaccines that provide a clinical benefit to 40% of the vaccinated patients. This threshold, if reached in the absence of serious toxicity, would qualify immunotherapy as an additional standard treatment for cancer. To reach this objective, our project comprises three major activities. A first part of the project consists in clinical trials of vaccination, to compare various vaccines such as peptides and RNA, with different types of immunological adjuvants, and dendritic cells. Safety and clinical efficacy will be the primary endpoints of these trials. A large effort will be devoted to monitoring the anti-vaccine T cell responses, as examining the correlation between immunological and clinical response s to the vaccines will be crucial to understand which factor(s) limit tumour regression.A second part of the project, tightly connected to the clinical trials because it uses biological material from the vaccinated patients, consists in optimising tumour vaccines and combating immune evasion. Foreseeable mechanisms of tumour escape will be analysed and correlated with the clinical results. Improved modalities of vaccination will be tested, and new target antigens will be identified. All these results will help to design improved vaccines. Finally, considering the complexity of mechanisms that may lead to or prevent tumour regression in vaccinated patients, we propose to explore more fundamental aspects of the anti-tumour immune response. This includes the cross presentation of tumour antigens by dendritic cells, recruitment of cells of the innate immune system, involvement of suppressor T cells, and development of murine models of inducible tumours. If new concepts emerge from this work, they will also help t o design bet
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Next generation optical network for Broadband in Europe' (NOBEL) targeting Sixth Framework.

assistant: **Abstract**

To achieve the strategic goal of broadband for all an appropriate optical core/metro network infrastructure is required to aggregate end-users communication traffic and ensure an end-to-end transport with the desired level of quality. The main goal of the IP NOBEL is to carry out analyses, feasibility studies and experimental validations of innovative network solutions and technologies for intelligent and flexible optical networks, thereby enabling broadband for all.Specifically, the main objectives are: to define network architectures, evolutionary guidelines and a roadmap for core/metro optical transport networks towards intelligent data centric solutions (e.g.ASON/GMPLS); to identify main drivers for the evolution of core and metro optical networks supporting end-to-end broadband services and to derive technical requirements; to study efficient traffic/network engineering and resilience strategies in multi-layer/domain/service networks and interworking issues; to assess and describe social and techno-economic aspects regarding the deployment of network solutions and technologies for intelligent and flexible optical networks; to evaluate solutions for providing end-to-end QoS; to identify network architectures, concepts and solutions for advanced packet/burst switching; to propose simplified strategies for the end-to-end management and control of intra/inter-domain connections in multi-layers networks (e.g. IP overOptics); to find enhanced solutions and technologies for physical transmission in transparent optical networks; to identify the key functional requirements from the architectural, management, control and transmission viewpoints and translate them into specifications, feasibility studies and prototype realizations for multi-service/multi-layer nodes with flex
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Site for training intraffic, modelling and safety' to be submitted under Fifth Framework.

assistant: **Abstract**

An opportunity to contribute to research excellence in Traffic, Transport Modeling and Safety: Applications are invited from PhD research students registered outside the UK wishing to spend part of their study within the Traffic, Modeling and Safety research group at the Institute for Transport Studies (US), University of Leeds, UK. This is one of the foremost groups within the field in the UK, with a research income of 5m Euros over the last 4 years. ITS is a leading UK interdisciplinary transport research Institute involved in a wide range of teaching and research. The quality of research is continued by its achievement of the highest rating (Grade 5*) for research (1996Research Assessment Exercise). Fellows will be encouraged to develop their own research themes that are likely to be linked to one of the following areas: transport and the environment traffic modeling and prediction, transport data collection and analysis, network modeling, micro simulation, safety and impacts of new technologies, systems to enhance safety, behavioral modeling, stated preference, traffic management, travel time variability and incidents. As part of the EU funded Marie Curie Fellowship scheme, visits normally last for 6 months. Specific benefits and facilities available to Fellows include: the SATURN and DRACULA modeling software, the Leeds Advanced Driving Simulator, live data on traffic, signals, meteorological conditions and a quality through the Instrumented City, state of the art equipment through LANTERN (Leeds Health Air pollution, Noise, Traffic and Emissions Research Network), the support of an established international postgraduate student community, outstanding research library and other University of Leeds facilities, seminars, workshops, taught modules and short courses of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Development of novel inhibitors of the anti-infective target DXS using dynamic combinatorial chemistry (DCC)' under Horizon 2020.

assistant: **Concept**

The emergence of multi-drug resistant pathogens is a serious global problem. In this alarming situation, novel targets for which inhibitors with an unprecedented mode of action can be developed are urgently required. This proposal aims at the development of selective and potent inhibitors of the important and underexplored anti-infective target DXS, an enzyme from the 2C-methyl-D-erythritol 4-phosphate pathway that is entirely absent in humans but is essential for medically relevant pathogens (e.g., Plasmodium falciparum, Mycobacterium tuberculosis, Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus). Despite substantial efforts dedicated to the discovery of inhibitors for DXS, to date very few active compounds have been reported and none of them fulfil the requirements as an ideal candidate for further development. To address these issues and maximise the chances of success, we will use dynamic combinatorial chemistry (DCC) as a hit identification strategy for the first time for the enzyme-DXS. To explore hitherto unexplored parts of the chemical space, we will pioneer the use of chiral heterocyclic building blocks in DCC for the discovery of potent inhibitors of the enzyme DXS. Use of chiral heterocycles in DCC will allow to rapidly access novel scaffolds. These chiral heterocyclic scaffolds will be evaluated for their biochemical activity on bacterial DXS. The most promising candidates will be tested in in vivo cell-based assays in bacteria.The proposed approach for the design of chiral heterocyclic inhibitors for novel targets such as the enzyme DXS will enhance the knowledge about this underexplored target and will open up access to various potent inhibitors. Hence, this research programme will greatly improve the chances of idnetifiying new ant