RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Euroscience Open Forum 2014' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

Euroscience Open Forum (ESOF) is a biennial pan-European scientific meeting staged to provide an interdisciplinary forum for open debate and discussion on the role and future of scientific research, education and innovation.The ESOF meeting has taken place every second year in a major European city since 2004. ESOF 2014 will take place from the 21st to the 26th of June 2014 in Copenhagen with up to 5,000 delegates. To capture the essence of ESOF, the 2014 edition will be entitled ‘Science Building Bridges’. The bridge is a symbol of the vision of ESOF 2014: closing the distance between science and society, while forging a European scientific integration.ESOF 2014 will:• emphasize public debate, collective reasoning and reflection as intrinsic to the democratic community.• promote awareness of European science and engage the scientific community in Europe and globally.• honour the expectations of the various ESOF delegates by offering inspiring conference formats and state-of-the-art sessions addressing major global issues, e.g. health, resource management, and green economy.• increase the level of integration between the different target audiences – scientists, politicians, journalists, students and the public.All elements in the Copenhagen conference concept are part of an overall move towards a tighter integration of science, innovation communication and public engagement.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Meta-Analysis of Chemotherapy in Head and Neck Cancer: a study based on updated individual data from more than 10.000 patients', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

This international work initiated by an European country aims to evaluate the effect of chemotherapy on survival in patients with squamous cell head and neck carcinoma by performing a meta-analysis, or synthesis, of all randomized trials, published or not, comparing loco-regional treatment with loco-regional treatment plus chemotherapy.Head and neck carcinomas (HNC) are frequently occurring tumors with 60 000 new cases (oral cavity, oropharynx, hypopharynx, larynx) per year in the European Community. These diseases have often a locally advanced stage at diagnosis. Despite loco-regional treatment with surgery and/or radiotherapy the prognosis of HNC patients remains poor with less than 30% of patients with locally advanced disease surviving 5 years.More than 60 trials have been performed between 1965 and 1993, but the question of the efficacy of chemotherapy on survival remains open to debate. Half of the trials have been performed in the European Community. Most of the individual trials have not been large enough to distinguish between an ineffective treatment and a moderate effect on survival. The study will be based on updated individual patients data sent by trialists. Given the incidence of head and neck cancer, a moderate improvement of survival (5-10%) could prolong the life of thousands of patients world-wide each year.In a second meta-analysis, the role of chemotherapy in the avoidance of mutilating surgery of the larynx will be studied. Larynx preservation is a high priority in clinical researchbecause of its importance in the quality of life of patients.These 2 meta-analyses will give a unique opportunity to compare its results with the results of a literature-based meta-analysis. The latter is more rapid and cheaper, but more prone to biases leading to potent
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Application of a systems design automation tool to embedded software control systems' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Elm Ltd is a UK based SME designing and manufacturing retail refrigeration and HVAC (HEATING, VENTILATING AND AIR CONDITIONING) control systems. The success of the company is largely based upon its ability to respond to individual customer requirements. The flexibility of Elm's product range is dependent on its software engineering capability. The changing nature of the market and the strict deadlines imposed by customers for new store openings, requires a fast, efficient and dependable software development process. Project overrun, specification errors and implementation errors lead to customer frustration and possible loss of future business.The main objective of the PIE is to improve the process of designing embedded software control systems. This will be achieved by improving the system design process and ensuring its uniform application by modifying existing processes and training and motivating staff. The adoption of a design automation tool that will largely replace the present manual process of implementing requirement specifications will greatly assist the PIE. The benefits derived from this PIE to Elm can be obtained by many other companies engaged in similar developments and at a similar stage of software quality maturity. Elm is typical of many SMEs, both in the UK and across the European Community. It is hoped that the dissemination of our results shall benefit many other similar organisations.THE EXPERIMENTThe PIE involves the application of an improved design process with the aid of a System Design Automation toolset to a baseline project which is the design of an Air handling Unit (AHU) embedded controller. This addresses two of the major deficiencies identified during the review of current software practices: project overrun and unplanned design iterati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Establishment and refinement of sensory innervation in the lateral-line system of the zebrafish' (2007-2013) under Seventh Framework.

assistant: **Objectives**

The establishment of sensory-organ innervation is crucial for behaviour, social interactions and survival. Neuronal arborisation is dictated by signals that guide neurites to their appropriate targets in combination with the spatial distribution of the target cells. To date, most emphasis has been placed on the genetic bases of neuronal-type specification and organ formation during embryonic development and, consequently, there is a serious gap in our knowledge about the long-term dynamics of organ innervation. To advance towards this goal, we will need to elucidate whether and how neuronal activity and sensory organ architecture can modulate neural arborisation. Vertebrate sensory organs represent an excellent model to study the establishment and maintenance of organ innervation. To investigate these processes, I have chosen the zebrafish mechanosensory “lateral line” as a model system. In general, planar polarized sensory hair cells in each unit of the lateral line, called neuromast, receive innervation by two afferent neurons. Hair cells can regenerate and re-innervate very rapidly, providing a simple model of sensory neurons arborisation whose dynamics can be visualized in vivo over long periods and under normal or altered physiological conditions. To investigate the mechanisms that govern the acquisition and maintenance of hair-cell innervation, I will conduct a systematic and comprehensive study of the processes that underlie the elaboration and remodelling of sensory-neuronal architecture in the lateral-line organ. I will perform high-resolution live imaging combined with sophisticated techniques to permit spatio-temporal control of protein expression. The findings derived from these studies shall reveal the mechanisms by which animals maintain sensory abilities
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Democratising and making sense out of heterogeneous scholarly content'.

assistant: **Objectives**

SciLake's mission is to build upon the OpenAIRE ecosystem and EOSC services to (a) facilitate and empower the creation, interlinking and maintenance of Scientific/Scholarly Knowledge Graphs (SKGs) and the execution of data science and graph mining queries on top of them, (b) contribute to the democratization of scholarly content and the related added value services implementing a community-driven management approach, and (c) offer advanced, AI-assisted services that exploit customised perspectives of scientific merit to assist the navigation of the vast scientific knowledge space. In brief, SciLake will develop, support, and offer customisable services to the research community following a two-tier service architecture. First, it will offer a comprehensive, open, transparent, and customisable scientific data-lake-as-a-service (service tier 1), empowering and facilitating the creation, interlinking, and maintenance of SKGs both across and within different scientific disciplines. On top of that, it will build and offer a tier of customisable, AI-assisted services that facilitate the navigation of scholarly content following a scientific merit-driven approach (tier 2), focusing on two merit aspects which are crucial for the research community at large: impact and reproducibility. The services in both tiers will leverage advanced AI techniques (text and graph mining) that are going to exploit and extend existing technologies provided by SciLake's technology partners. Finally, to showcase the value of the provided services and their capability to address current and anticipated needs of different research communities, four scientific domains (neuroscience, cancer research, transportation, and energy) have been selected to serve as pilots. For each, the developed services wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Jumbo Phages In Translational Enzyme Research' to be submitted under Horizon Europe.

assistant: **Abstract**

Jumbo phages are large viruses of prokaryotes with 200 to 800 kilo base-pair (kb) genomes, well beyond the size of small phages that average around 50 kb. While investigation of small phages over the last  century has transformed fundamental and translational biosciences, jumbo phages research is only in its infancy. The majority of jumbo phage genes are uncharacterized and cannot be annotated by comparative genomics. Thus, it is unknown how the genes function in jumbo phage biology. Importantly, jumbo phages generally carry genes to take over their hosts transcriptional and translational machinery, in addition to harboring factors that may modify and degrade nucleic acids. Many of the unannotated genes might have similar characteristics, which could be exploited for translational enzyme research. However, those genes remain experimentally under-explored.The JUPITER project tests the hypothesis that some of the uncharacterized genes have properties that affect their hosts transcriptional and translational machinery, and that some of the gene products could modify or degrade nucleic acids. Using an innovative high-throughput in vitro characterization strategy, I will experimentally annotate gene products of unknown function according to their ability to catalyze the above-mentioned reactions. Known and novel jumbo phages will be isolated and characterized to expand our current knowledge of jumbo phage biology. Promising candidate factors will be characterized in vitro and in vivo to understand their function and to facilitate translational enzyme research.My results will provide (i) an innovative method for experimental gene annotation, unraveling new mechanisms in jumbo phage biology, (ii) an expansion of the available jumbo phage diversity and (iii) detailed insights i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Thematic network advanced manufacturing systems II - extension of the existing TEAMS thematic network' (1994-1998).

assistant: **Concept**

TEAMS II PROJECT OVERVIEW The extension TEAMS-II adds 11 further running Brite-Euram projects to the existing Thematic Network - Advanced Manufacturing Systems (TEAMS). The structure of the Thematic Network is enlarged. The horizontal approach of this network will bring together end users, machine builders, suppliers and research institutes structured in different clusters. All participating parties will contribute to the dialogue between the various projects in each cluster as well as between different clusters in the network. This Thematic Network is intended to contribute actively to European co-ordination of R&D efforts. TEAMS II allows to join the efforts in labour intensive sectors and to initiate innovations in order to maintain European manufacturing industries competitive. The real time" exchange of information on technological aspects of related projects will lead to much better R&D co-ordination and establish itself a network of very strategic importance. The included projects will increase the future exploitation of results and will be motivated to reach the settled targets due to the links to other similar and parallel conducted projects. The clustering reflects the awareness of future technology trends regarding major industry objectives in improved manufacturing. The triangle of cost, quality and time, which are major industry and business constrains, needs a market orientated answers in form of new processes, reliable systems and concrete applications for lead-time EUROPEAN DIMENSION AND PARTNERSHIP The European machine tool sector consists of a large majority of small and medium sized enterprises. In front of international competition, the technological leadership of European industry is still a key element for a strong market position. The business env
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Smart pathology slide scanner for diagnosis and patient-specific treatment recommendation in oncology' (CancerScan).

assistant: **Innovation**

Our long-term vision is to develop a smart digital pathology slide scanner that can (semi)automatically generate a patient-specific tumour digital twin and simulate various drug treatments on such twin. The digital twin will be generated by combining slide-level multi-omics profiling of patients’ biopsies with other standard clinical data and will be hardware-embedded within a slide scanner.This foundational architecture involves five pillars: experimental mapping of tumor communication, reconstruction of Biomedical Knowledge Graphs (KG) based on experimental data, identification of structural and temporal properties of communication networks, development of a mathematical framework for modeling treatment effects on a tumor, and the design of a novel hardware acceleration architecture for a medical digital twin. As a model system, we will use pancreatic cancer, combining in vitro experiments with clinical data. We will analyze how tumor microenvironment composition affects cellular crosstalk and drug efficacy by developing, growing, and treating a series of tumor organoids with different TME compositions, and performing a detailed molecular analysis of samples. Clinical validation will involve matching organoid and patient biopsy structures, ensuring relevance and applicability of our findings. This project is the initial step towards a platform assisting doctors in improving the diagnosis and assessment of drug treatment efficacy for individual cancer patients so that each patient gets the best possible drug, with the best possible treatment regimen.


**Keywords:** tumor microenvironment, cellular crosstalk, AI, digital slide scanner, tumor proto-communication, digital twin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Multifunctional Magnets Through Rational Design'.

assistant: **Innovation**

The aim of this project is to rationally design innovative multifunctional magnetic framework materials using new metalloligand and organic radical groups.  This will  lead to tailored magnetic properties with potential application in a range of fields, such as data storage, computing and spintronics.  The metalloligand and radical groups are specially designed to impart specific magnetic interactions and function to the frameworks.  This has the two-fold advantage of not only using the material for sensing external stimuli, but post-synthetically modifying the magnetic properties of the materials.  The highly innovative goal is the realisation of multifunctional materials for applications in fields where tailored and tuneable magnetism is advantageous
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'NEW GENERATION OF BIPV-GLASS WITH ADVANCED INTEGRATION PROPERTIES' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

This project proposal starts to walk pursuing to accomplish the following main general objective: to overcome the main limiting factors of BIPV technology strengthening its competitiveness by developing new generation PV glazing satisfying the well-defined market demanded architectural trends. ONYX will face this main goal by developing a new family of products referred as Novel XL-BIPV glazing units, High-Mechanical Resistance PV units and high performing vision glazing based on PV thin film transparent panes (transparency over 50%) being market ready within the 24 forthcoming months. During the lifetime of the project, main challenges will be faced and overtaken by well-defined approaches. Out of the technical challenges ONYX will establish a very well defined commercialization and marketing strategy targeting global markets and main green building and architectural glazing stakeholders. ONYX ambition will be reaching the blue ocean concept. In other words, by developing BIPV products with undeniable added value achieving a clear market differentiation from our competitors leading to a greater range of coverage of the architectural glass industry, gaining the attention of prestigious end users as clients, and promoting a sense of market dominance by offering products that others cannot. The final goal will be achieving a 4,3% market share of the global BIPV business by 2020. It means to double or quadruplicate our actual share of 1% in a market that will grow from $823 million ($US) in 2014 to $2.7 billion in 2019 (30% growth/per year). On the other hand, it should be pointed out that this project proposal fits perfectly with general EU policies in terms of sustainability as for instance Energy Performance of Building Directives. In summary, by executing this project
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'PUMA' under Seventh Framework.

assistant: **Concept**

Pressure forward bulkheads presently consist of different parts requiring an assembly process to get the final structure. Cost reduction can be achieved by using one shot injection technologies where an integrated skin-stiffening pre-form will be injected in one single shot. Further reduction of costs and energy consumption can be achieved by using Out of Autoclave resin systems. This proposal addresses the materials and processes to fulfil the requirements described in the topic description and indicates future trends related to the design and manufacturing of bulkhead manufacturing.