RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Concerted action in support of high quality non-human primate - nhp - breeding and biomedical research in nhp source countries' under Fourth Framework.

assistant: **Concept**

* To develop an organisational and communication framework between European and Developing Country primate research centres within which improvements in the capabilities for research on health problems of Developing Countries and improvements in animal welfare can most effectively be realised.* To identify the areas for improvement that can most benefit from collaborative efforts and co-ordinate the implementation of such efforts.Expected Outcome* Clearly identified priorities for collaborative development of research and reference capabilities.* Management and communication structures that allow rapid and free exchange of information between primate centres.* Co-ordination of the improvement of capabilities, ensuring that duplication of effort is substantially reduced and that optimal use of scarce resources is achieved.* Establish Regional Networks and appropriate regional centres for Latin America, Africa and Asia. Each regional centre will inform primate centres within the region of the establishment of PVEN and invite applications to participate in the network. Each regional centre will, together with the PVEN advisory board, select 5 - 6 appropriate members who will form the initial core membership of PVEN. A European co-ordinating centre will be established and the PVEN regional centres, together with this European centre, will invite independent experts to join an external advisory board for the network. * Hold regional meetings at which the opportunities for collaborative development of improved Research and Reference standards will be identified. Specifically the Reference Programme (published in PVEN Guidelines) will be used as a starting point for the evaluation of critical factors in: - colony health and management including virological, bacteriological, fu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Imaging synaptic contributors to dementia' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Alzheimer's disease, the most common cause of dementia in older people, is a devastating condition that is becoming a public health crisis as our population ages. Despite great progress recently in Alzheimer’s disease research, we have no disease modifying drugs and a decade with a 99.6% failure rate of clinical trials attempting to treat the disease.   This project aims to develop relevant therapeutic targets to restore brain function in Alzheimer’s disease by integrating human and model studies of synapses. It is widely accepted in the field that alterations in amyloid beta initiate the disease process. However the cascade leading from changes in amyloid to widespread tau pathology and neurodegeneration remain unclear.  Synapse loss is the strongest pathological correlate of dementia in Alzheimer’s, and mounting evidence suggests that synapse degeneration plays a key role in causing cognitive decline. Here I propose to test the hypothesis that the amyloid cascade begins at the synapse leading to tau pathology, synapse dysfunction and loss, and ultimately neural circuit collapse causing cognitive impairment.  The team will use cutting-edge multiphoton and array tomography imaging techniques to test mechanisms downstream of amyloid beta at synapses, and determine whether intervening in the cascade allows recovery of synapse structure and function.  Importantly, I will combine studies in robust models of familial Alzheimer’s disease with studies in postmortem human brain to confirm relevance of our mechanistic studies to human disease.  Finally, human stem cell derived neurons will be used to test mechanisms and potential therapeutics in neurons expressing the human proteome. Together, these experiments are ground-breaking since they have the potential to further our und
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Social innovation and light electric vehicle revolution on streets and ambient' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

The SilverStream project addresses the challenges associated with sustainable and affordable personal mobility for the growing and ageing population in congested European cities. The project combines both ergonomic concepts conceived for elderly people and advanced automotive technologies that are quiet, clean, energy efficient and safe. The particular objectives of SilverStream are: i) specifications related to the needs of urban and ageing population; ii) enhanced vehicle manoeuvrability for urban context; iii) sustainable ergonomics, health monitoring and adaptive HMI for minimum-fatigue vehicle operation; iv) dual voltage 12/48 V power network for modular and scalable E/E architecture; v) hybrid energy storage system for extended operating life and increased efficiency; vi) compact in-wheel drive units for light urban mobility solutions; and vii) maximizing project impact for enhanced European competitiveness.To achieve these objectives, the SilverStream project brings together 10 committed and complementary European partners that cover the whole value chain, including SMEs, large industry, academia and research institutes. The developed technologies will be driven by a team of expert in the field of medical and cognitive science domain through a top/down approach, and will be demonstrated with a vehicle prototype running in a realistic test environment.In conclusion, SilverStream will develop and demonstrate a radically new light and affordable vehicle concept (L-category). In doing so, SilverStream provides one possible mobility solution to address the tough challenges faced by Europe in relation to the field of air quality, noise and environmental protection, traffic congestion, competiveness and jobs preservation, as outlined in the specific challenge of the wor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Making Sense of Electrical Noise by Simulating Electrolyte Solutions' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Seemingly unrelated experiments such as electrolyte transport through nanotubes, nano-scale electrochemistry, NMR relaxometry and Surface Force Balance measurements, all probe electrical fluctuations: of the electric current, the charge and polarization, the field gradient (for quadrupolar nuclei) and the coupled mass/charge densities. If only we had the theoretical tools to interpret this electrical noise, we would open complementary windows on ionic systems. Such insight is needed, as recent experiments uncovered unexpected behaviour of ionic systems (electrolytes, ionic liquids), which question our understanding of these simple fluids and call for a fresh theoretical perspective. This project aims at providing an integrated understanding of fluctuations in bulk, interfacial and confined ionic systems. For modelling, the key challenge is to quantitatively predict the phenomena underlying the various sources of noise: coupled diffusion, long-range electrostatic interactions & hydrodynamic flows, short-range ion-specific effects (solvation, ad/desorption). Using molecular and mesoscopic simulations, I will provide a unified theoretical framework enabling experimentalists to decipher the microscopic properties encoded in the measured electrical noise. I will achieve this by addressing four interlinked questions corresponding to the above-mentioned experiments: 1) What is the microscopic origin of the coloured noise of electric current through single nanopores/tubes? 2) What do the charge fluctuations of an electrode tell us about the properties of the interfacial electrolyte? 3) What information can NMR relaxometry provide on the multiscale dynamics of individual ions? 4) Could collective fluctuations in concentrated electrolytes explain long-range forces between surface
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'CooperAtive Robot for Large Spaces manufacturing'.

assistant: **Concept**

The CARLoS project aims to apply recent advances in cooperative mobile robotics to a representative industrial scenario in shipyards. CARLoS robot will be built using off-the-shelf technology under a modular approach. The prototype will be demonstrated as a robot co-worker for fit-out operations inside blocks of ship superstructures.Most of technology for developing such a robot exists, but there is not yet a solution on the market with capabilities that meet the special requirements of shipyards. The CARLoS project will contribute to strength the technological level and market position of:-European SMEs that develop, supply, and integrate mechatronic, sensing, and electronic technologies for industrial applications.-European SMEs providing fit-out services to shipyards and to industrial and civil construction.The main features of CARLoS robot are:• high mobility inside ship blocks• semi-autonomous decision-making on the work to do• autonomous stud welding capability• autonomous pre-outfitting marking capability• easily controlled by a shipyard workerThe working plan has been designed to develop a full robot for stud welding and marking. The project is divided in 7 WP including RTD, dissemination and management tasks, comprising:• Development of a mobile navigation system for shipyard blocks• Development of a sensing and control system for full automation of marking and stud welding• Development of a skilled human-robot interaction system suited to the tasks at hand• Continuous integration towards a final prototype• Demonstration and validation of the system in real-world conditionsCARLoS will yield:• Higher flexibility, productivity, and reliability• Increase of the market share for the end users• Improved outfitting competitiveness• New market for high-tech products i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Altered brain-periphery crosstalk as a key pathomechanism for high-risk phenotypes in humans' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Diabetes is a leading cause for morbidity and mortality worldwide. In our fight against the diabetes pandemic, my team and I recently identified subgroups of humans that are predictive for future life-threatening complications even before diabetes onset. Classification into these new risk groups is currently purely based on extensive phenotyping, yet, the underlying mechanisms are unclear. Of note, phenotypes of very high-risk persons are highly reminiscent of those from subjects with altered periphery-brain communication. I will combine ground-breaking experimental research in humans with latest data analysis approaches to delineate the causal relationship between altered brain-periphery communication and very high-risk phenotypes.The 1st aim will reveal disturbances in the brain-periphery communication in high-risk persons. I will identify differences in the transduction of neuronal signals to the target organs, discover regulators from the brain to the periphery, and elucidate the regulation of underlying pathways. The 2nd aim will clarify signalling from the periphery to the brain. I will unravel the dynamic interaction between insulin and gut-derived hormones on the brain, identify signalling patterns that inform the brain about food intake and determine disturbances thereof in high-risk persons, and I will non-invasively characterize postprandial molecular responses in neurons. The 3rd aim develops a novel, non-invasive approach to identify high-risk persons by their altered brain-periphery communication. It will apply the above-generated knowledge to develop an algorithm-based integration of health data. Ultimately, my project will innovatively define the impact of altered brain-periphery crosstalk in the development of clinically relevant high-risk groups. It wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Functional foods and gut regulatory peptides and intestinal motility in human ageing' (1998-2002).

assistant: **Innovation**

Studies on animals indicate that gut to have a direct impact on neuron- endocrine secretion and gut motility. This project will investigate the role of pre- and robotics on the endocrine-endocrine and motility function of the elderly gut in order to improve the quality of life of the ageing human.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Advanced Display for Car Information Systems' (ADCIS) under Fifth Framework.

assistant: **Objectives**

The goal of this project is to develop Medium Voltage Field Emission Display (MVFED) as an alternative to AMLCD solutions in car information systems.Innovations are required to meet automotive requirements:- electron beam focusing in order to reduce the electron emission cone from the current 70 deg. to 20deg.,- stand off voltage technologies to bring the operating voltage from the current 3 V/micron to 4V/micron,- scrubbing technologies and getter solutions to achieve a lifetime exceeding 5000 hours.MVFED will be implemented into 7.0 inch diagonal demonstrators that will be evaluated with respect to automotive standards and that will be compared to other display technologies. AUDI plans to use it in its cars to solve the limitations of AMLCDs. The consortium will seek industrial partnerships in Europe for volume manufacturing.Technical results have already confirmed the feasibility and potential of the MVFED approach with prototypes demonstrated in operation at 3 to 4 KeV with very good brightness.Pixtech has recently annouced that MVFED will become their mainstream technology and confirmed their intention to industrialise it.Objectives:The goal of this project is to develop Medium Voltage Field Emission Display (MVFED) and to demonstrate that this new innovative technology meets the automotive market demand for an alternative to AMLCD solutions. By month 18, we will demonstrate 7.0 displays, fully qualified with respect to automotive standards with a peak brightness of 2000 cd/m2 before filter, a contrast higher than 3 at 50,000 lux (sunlight readability) and a life time exceeding 5000 hours in automotive use conditions - temperature range viewing angle and video speed being far ahead of AMLCD performances.Work description:In order to achieve the appropriate level of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'INCITE-DEM – Inclusive Citizenship in a world in Transformation: Co-Designing for Democracy' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

INCITE-DEM's experienced Consortium aims to enhance inclusive participation and civic engagement while expanding democratic innovation and dynamic feedback mechanisms between citizens and institutional actors in representative democracies. Currently, “wicked problems” relating to ecological crises but also media developments and digital divides create unprecedented pressures on democracies. Next to related socio-economic challenges, we’re witnessing a decline in political trust and the formation of new societal cleavages. INCITE-DEM will offer a unique contribution to the future of democracy in Europe by harnessing historical and quantitative and qualitative social science research, agent-based modelling, design thinking, and advanced analytical methods for the purpose of expanding inclusive participation and engagement and fuelling democratic innovation. Furthermore, we will implement Democracy Labs (DLabs) in six countries, where citizens, representatives of democratic innovation initiatives, policymakers, and other stakeholders come together to co-create imaginaries of inclusive democratic innovations. The new solutions and democratic futures envisioned are the objects of design fiction products. All innovations co-created in the DLabs are then validated through a choice experiment survey with citizens and interactive fora with policymakers, to check their feasibility and the potential for implementation. Lastly, a set of policy roadmaps for a sustainable, inclusive, and innovative democracy in a world facing deep societal, technological and ecological transformations are produced and presented to a broad range of stakeholders at multiple levels of governance in Europe.


**Keywords:** inclusivity; digitalisation; sustainability; historical review; democratic innovat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'The Collaborative Seismic Earth Model Project'.

assistant: **Innovation**

Seismic tomography images of the Earth's interior are key to the characterisation of earthquakes, natural resource exploration, seismic risk assessment, tsunami warning, and studies of geodynamic processes. While tomography has drawn a fascinating picture of our planet, today's individual researchers can exploit only a fraction of the rapidly expanding seismic data volume. Applications relying on tomographic images lag behind their potential; fundamental questions remain unanswered: Do mantle plumes exist in the deep Earth? What are the properties of active faults, and how do they affect earthquake ground motion?To address these questions and to ensure continued progress of seismic tomography in the 'Big Data' era, I propose new technological developments that enable a paradigm shift in Earth model construction towards a Collaborative Seismic Earth Model (CSEM). Fully accounting for the physics of wave propagation in the complex 3D Earth, the CSEM is envisioned to evolve successively through a systematic group effort of my team, thus going beyond the tomographic models that individual researchers may construct today.I will develop the technological foundation of the CSEM and integrate these developments in studies of  large-earthquake rupture processes and the convective pattern of the Earth's mantle in relation to surface geology. The CSEM project will bridge the gap between regional and global tomography, and deliver the first multiscale model of the Earth where crust and mantle are jointly resolved. The CSEM will lead to a dramatic increase in the exploitable seismic data volume, and set new standards for the construction and reproducibility of tomographic Earth models.Beyond this project, the CSEM will be openly accessible through the European Plate Observing System
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Largish molecules on surfaces : basic properties and applications in molecular electronics', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

Fast - scanning, variable temperature STM will be used to perform investigations of the interaction of largish carbon - based molecules on both metal and semiconductor surfaces, providing a better understanding of the fundamental diffusion processes and guidance towards applications in Molecular Electronics.