RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Site-dependent life-cycle impact assessment of human toxicity and acidification'.

assistant: **Concept**

In current environmental life-cycle assessment of products, little attention is paid to the site where an emission is released. It is expected that the relevance of the assessment process can be enhanced by the addition of a few general equivalence factors. Each link in the cause effect chain can be characterised by a set of descriptors. As a first step, the main descriptors will be identified and their variance will be described. Next, for these descriptors the related discrete situations will be defined. For these situations equivalence factors will be established that express the equivalent influence of a reference situation. These equivalent factors will be used to develop generic, feasible and easy to handle methods and procedures for site-dependent life-cycle impact assessment of human toxicity and acidification.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Drugs and Precursor Sensing by Complementing Low Cost Multiple Techniques' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

A large number of techniques have been developed in the latest decades, which are able to screen and identify specific molecules for drug precursors detection even at very low concentration in lab testing.Nevertheless the objective to build up a system which proves to be easy to use, compact, able to provide screening over a large number of compounds and discriminate them with low false alarm (FA) and high probability of detection (POD) is still an open issue.The project will focus on employing multiple techniques, integrating them in a complex system which employs them in a complimentary approach in order to identify an optimum trade-off between opposite requirements: compactness, simplicity, low cost vs. sensitivity low false alarm rate, selectivity. Known techniques, as fluorescence will be improved by mean of novel proteins, as antibodies to extend Probability of Detection (PoD). The techniques are: 1. A low cost, high data throughput sensing technique, based on UV-Vis-NIR fluorescence. Fluorescence will be enhanced by development of Organic macro-molecules sensitive to specific classes of compounds of interest (ephedrine, pseudoephedryne, P2P, …) in the domain of drug detection. The fluorescence analysis will be based on an ‘opto-chip’ which can incorporate an array of different properly engineered fluorescent chemical protein able to bind to the analytes with an ‘immuno-type’ reaction. An array of classes of compounds can be thus very fast discriminated by one-shot measurement. 2. A high sensitivity and selectivity, but compact and low weight, spectroscopic sensing technique in MIR–IR optical range, based on Laser PhotoAcoustic Sensor (LPAS). Detection of drug precursors based on spectroscopic techniques can guarantee a good selectivity, a low Probability of False
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'IN2TRACK3' (IN2TRACK3) targeting Horizon 2020.

assistant: **Abstract**

The European railway industry faces great challenges in need for increased network capacity. Ageing infrastructure assets require efficient and sustainable interventions to maintain and improve current levels of performance. To meet these demands and increase the operational performance of the railway infrastructure assets, innovation is needed to enable a step-change in reliability, availability, maintainability and safety (RAMS) and also to optimise asset capital and LCC. The IN2TRACK3 proposal addresses the topic of “Research into optimised and future railway Infrastructure” of the 2020 Horizon 2020 SHIFT2RIL call. The project is a continuation of IN2TRACK and IN2TRACK2 and aims to further develop and demonstrate research results and innovations developed. IN2TRACK3 will develop physical as well as digital technology and methodology demonstrators for the Track, Switches & Crossings and Bridge & Tunnel assets and the project is aligned to the SHIFT2RAIL overall aims. The project structure is designed around three technical sub-projects aiming at both improving the operational performance of existing infrastructure assets and providing radical new system solutions delivering a step-change in performance, improving methods and repair techniques, improve quality, reduce costs and extend the service life of assets and structures. The project is led by Trafikverket, the Swedish Transport Administration Agency, the consortium consists of 27 expert partners originating from 11 European countries and the partners involved are infrastructure managers, research partners, technology developers and industry partners. IN2TRACK3 will further develop and demonstrate a number of innovative solutions based upon the two previous projects and the work will build upon already ongoing mut
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Sustainable On-site and Innovative Technologies for Advanced Transport BioFuels from MιcroalGae' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

TThe FuelGae project aims to develop a novel model of advanced liquid fuels (ALF) production from different CO2 emissions streams of two industrial sectors (biorefinery and energy intensive industries) through a microalgae pilot plant integrated into their infrastructure. The performance of the selected microalgae strains will be improved by adapting them to each industrial case study. The ALF production will be addressed developing  different technologies: i) selective production of microalgae to obtain polysaccharides or lipids, ii) alternative microalgal biomass treatments, iii) innovative catalytic upgrading systems from biocrude., iv) online microalgae sensor. Additionally, to the previously innovative technologies, FuelGae concept uses modelling techniques integrated into Process Analytical Techniques to develop a global Digital Twin (DT).Furthermore, the C-economy of FuelGae approach will be significantly improved through hydrothermal liquefaction and, biogas processes. The biochar produced will be tested in agricultural uses creating synergies with energy and biocrude generation. All technologies will be upscaled to TRL5 in the two case study sites; the microalgae pilot plant will be transported and validated in the two industrial sites in Romania (steel plant) and Spain (2G-bioethanol). FuelGae technologies will be further evaluated through life cycle assessment (LCA/LCC) to confirm their lower environmental impact, use of resources, or GHG emissions, and a first approach of economical sustainability. DT will be coupled with LCA-LCC to provide a global and dynamic assessment of the FuelGae concept.FuelGae will contribute to advancing the European scientific basis and global technological leadership in the area of renewable fuels, increase their technology compe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'A mosaic screen for genes regulating neural stem cell divisioins in the developing adult central nervous system of Drosophila' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

Neural stem cells have the capacity to generate vast numbers of neuronal progeny over long periods of time when cultured in vitro, yet during normal development this mitotic potential must be kept in check so that each region of the central nervous system contains the appropriate number of neurons and glia. As neural stem cells have the remarkable capacity of regenerating the damaged brain, understanding the developmental regulation of their divisions may have important implications for future stem cell-based therapies. The remodelling of the Drosophila central nervous system (CNS) from its larval to adult form provides a genetically tractable system for studying region-specific proliferation at the level of individual neural stem cells, termed neuroblasts. Using in vivo clonal analysis, our lab recently explored the nature of the stop mechanism limiting how many times a postembryonic neuroblast (pNB) can divide. These studies have identified a pathway linking a conserved family of positional information genes, the Hox genes, to the developmental time at which neural proliferation ceases. The purpose of my project is to conduct a genome-wide mosaic screen to identify new genes that are also involved in regulating neural stem cell divisions.This will take advantage of several genetic tools and particular strains of Drosophila that have been developed in the host laboratory recently. New stem cell division genes will be characterised at the genetic and molecular level and their vertebrate orthologues studied in the context of hindbrain development.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'ReActor for Process heat, Hydrogen And ELectricity generation', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

The Project addresses the viability & performance of the Very High Temperature Reactor (VHTR). This innovative system is not only meant at competitive & safe power generation, but also at industrial process heat supply, in particular for hydrogen production. It offers significant advantages with its inherent safety features and the related simplification of the system, its robust fuel without significant radioactive release, its high efficiency and use of any fissile/fertile material. explored to achieve the challenging performances required for VHTR (900-1000°C, up to 200 GWd/t). The selection and qualification of materials for very high temperature components, graphite internals and vessel is a key area of the Project. The critical components (in particular the intermediate heat exchanger) are developed. The demonstration of the unique robustness of the fuel is extended to higher temperature & burn-up. The fabrication of advanced fuel with higher performances is tested. The irradiated fuel behaviour in disposal conditions is studied. Computer tools for reactor physics, safety analysis and fuel behaviour are qualified through comparison with experimental data including those resulting from tests planned in the Project. Moreover the modelling of the fuel irradiation behaviour is improved. A safety approach adapted to the specific features of modular VHTR is elaborated. Finally an evaluation of the viability & performance of the whole system is achieved.This programme has been set-up to compliment and support European national VHTR programmes and to contribute to the international effort on GENERATION IV VHTR projects. As the Project addresses issues raising major concerns for the future (energy and fresh water supply, climate change, natural resource preservation), it w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Photophysical Applications of Nano-Optics to Molecules' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

In the strong light-matter interaction regime, a quantum emitter exchanges energy with an electromagnetic resonator in a reversible, coherent manner. In this unique situation the separated wavefunctions of the two entities are no longer the eigenstates of the Hamiltonian and one resorts to a ""dressed atom"" approach, where the degenerate energy level splits into two new coupled states. Similarly, dye molecules embedded in a photonic nanostructure may interact resonantly with it to produce a hybrid system with new energetic states known as cavity-polaritons. The formation of such mixed light-matter states is a subject of on-going research since the mid 1980's, studied with atoms, semiconductors, electronic spins in NV centers and more. However, with organic molecules, new opportunities arise, which lay at the interface between physics and chemistry: the creation of new states and the rearrangement of the molecular energy landscape can modify chemical and material properties. This is a new concept, recently introduced, and which may be used for tailoring material properties for specific purposes. In this proposal I will pursue several avenues under the framework of strong interactions of molecules and light, and in particular I will development novel methods to control chemical reactions by strong coupling. I will examine the use of the coupling to plasmonic nanostructures for manipulating the triplet formation in organic dyes. By that I will be able modify the branching ratio for various processes in such molecules – phosphorescence quantum yield or chemical reactions evolving through the triplet state. In addition, I will study the transport properties of molecular films strongly-coupled to surface plasmons, and the spatio-temporal dynamics of such hybrid systems.The g
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Intermarriage and ethnic identity'.

assistant: **Innovation**

An important element of social cohesion and contact between majorities and sub-state ethnic minorities are intermarriages, which are either welcomed as vehicles easing the tensions between nations and sub-state minorities, or criticized as important drivers of assimilation and the destroyers of ethnic minority communities. The social aspects, family dynamics and identity construction of family members in intermarriages were not studied methodically in CEE and the WB. Therefore, the goal of the Intermarriage and Ethnic Identity (IMEI) project is to analyse the social implications of intermarriages between members of ethnic minority communities and the majority nations in Vojvodina, the multiethnic region of Serbia. The IMEI project will contribute to the state-of-the-art by analysing the social impacts of intermarriages on three levels, namely the individual (micro), the family (meso) and the societal (macro) in a significantly multi-ethnic geographic region. On the individual level the project will examine ethnic and cultural identity transformations undergone by partners in intermarriages. On the family level we will explore the processes of intergenerational transfer of ethnic, religious and cultural markers. On the societal level the project will investigate the workings of the relevant and quite modern ethnic minority policies and legal framework of Serbia and their impact on intermarriages. This research is relevant in the wider European context as well, as we will specifically target the Hungarian, Slovak and Romanian ethnic minorities living in Vojvodina, whose kin-states (Hungary, Slovakia, Romania) are members of the European Union, whose members often have dual Serbian and EU citizenship and are therefore subject to the Framework Convention for the Protection
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Computer aided de novo design of nanobodies' (Nanodesign), addressing dissemination and exploitation.

assistant: **Impact**

Antibodies have become major players in the pharmaceutical industry and were valued at 0.16 US billion in 2023.  Traditionally, antibodies are obtained after immunisation of different animals and then produced in relevant cells for use in research, diagnostics and therapy. In recent years, there is a growing public opinion in Europe to ban the use of animals for biomedical research, and therefore there is an increasing pressure to move from animal produced antibodies to design and produce them in vitro.  Antibody engineering has another important advantage, which is the possibility of targeting a precise epitope and not rely on serendipity as when injecting an animal with an antigen. In recent years, there have been significant advances in protein design based on the use of artificial intelligence and precise force fields.  Despite this, the majority of the companies that work on antibody design combine rational engineering with massive proprietary screening methods, and so far, there are no reported cases of fully de novo design of an antibody with nM affinity against a defined epitope. Using an interleukin receptor as a case study, we have shown that we can indeed fully design de novo a nanobody that recognizes the target with nM affinity, using our proprietary protein design software FoldX and ModelX. Experts consulted to date indicate that the results obtained so far are truly impressive, prompting us to continue validating and optimising our process. Our proposal has two main objectives: First, to fully automate our pipeline that involves epitope selection, antibody framework selection and docking, backbone move and side chain search. Second, demonstrate that our optimised pipeline can design fully de novo nanobodies against a defined target in a fast and cost-effe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Concerted action on offshore wind energy in Europe' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The overall objective of the project is to support the realisation of offshore wind energy by mobilising available but scattered knowledge from previous/on-going National and EU efforts, upgrading this knowledge into coherent views and disseminating the results back into the offshore wind energy community.The specific objectives are to:- exchange information within the EU member states,- provide an inventory of the state-of-the-art on key issues,- provide recommendations for RTD programmes and implementation of large offshore wind farms, both with national and EU DGXII / XVII dimensions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'FLooding Accident REsponse' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The FLARE consortium comprises key stakeholders from industry, academia and policy makers, involved in ship flooding risk research as a Group for over twenty years (HARDER, SAFEDOR, GOALDS, EMSA III, eSafe), the latter three focussing on passenger ships. This offers a unique knowledge base and capability to support targeted new developments and expedite implementation. The overriding objective is to develop a Risk-Based methodology for 'live' flooding risk assessment and control, to be achieved by: - Creating an updated accident database for passenger ships and damages. Using this with support from suitably verified flooding simulation tools to develop a generic risk model for flooding incidents, accounting for collision and grounding with focus on cost-effective risk containment in emergencies.  - Ensuring the risk model is generic (all incidents in one model), holistic (active and passive measures) with potential application to newbuildings and existing ships. - A risk-aware approach post-flooding incidents from susceptibility to flooding to emergency response, including mustering and abandonment in extreme flooding scenarios.    - Innovative technical solutions at TRL5 in ship concepts and equipment targeting risk containment, including: crashworthiness; minimising the risk from WT doors; use of highly expandable foam post-incident; decision support for crisis management.  - Developing a proposal for the revision of relevant IMO regulations towards a risk-based approach to contain and control risk in passenger ships from flooding incidents.


**Keywords:** Flooding, probabilistic damage stability, risk models, grounding, collision, risk-based design and operation, life-cycle risk management, fatalities, evacuation, crashworthiness, Goal-Based Standards