RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'A device that will dramatically improve the protection of babies during birth. It will monitor the child continuously with better acuity, resulting in better clinical outcomes at a lower cost.' (RepHorm) targeting Horizon 2020.

assistant: **Abstract**

The objective of this Phase 1 application is a feasibility study to assess the commercial viability of RepHorM, and quantify the business opportunity. This project is to develop a real-time in vivo infant monitor that safe guards the baby during birth. This achieved with a fiber optic based biomarker sensor. This device will for the first time provide doctors with a real-time, continuous and objective measure of a baby’s health during labour by incorporating this technology into an existing medical device. The learning curve will be small in taking up the new device and the specific biomarker, is very familiar to obstetricians as well as other clinicians, and the threshold levels for intervention are already established. This Innovative solution uses latest technology deployed to an old, long standing problem. The research into the sensor chemistry has been now completed and this activity has moved the technology form TRL 3 to the current TRL 6. The worldwide market for monitoring was €6.2 Billion in 2010 and is predicted to increase by 4.4% compound annual growth rate (CAGR) to reach € 8 Billion in 2016. None of the current methods offer clear advantages over one another. The general trend in medicine is towards individual bedside or in-patient testing of key biomarkers, in particular, there is a trend towards continuous bio-diagnostics. BlueBridge Technologies hope to use Phase 1 to identify obstacles to successful product development and launch, and develop solutions to manage them. The work will then serve to better understand and describe exactly what type of product(s) the market requires and subsequently estimate the development costs, time to Market and provide the inputs needed for a Phase 2 application.Babies and the market need this product as they are curren
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Ecosystemic knowledge in Standards for Hydrogen Implementation on Passenger Ship' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

Hydrogen fuel cells market potentials in the maritime sector have been demonstrated in the last years with several vessels flagship projects. Despite hydrogen is a worldwide considered a valid option to reach the emission reduction targets, also part of the International Maritime Organization (IMO) strategy, a regulatory framework applicable to hydrogen fuelled ships is not yet available. E-SHyIPS brings together the Hydrogen and maritime stakeholders and international experts, through an Advisory Board, to gather new knowledge based on regulatory framework review and experimental data on ship design, safety systems, material and components and bunkering procedures. The approach is ""vessel independent"", in order to avoid the burdens of customized projects, and is focused on the risk and safety assessment methodologies.  Based on this, e-SHyIPS will define a pre-standardization plan for IGF code update for the hydrogen-based fuels passenger ships and a roadmap for the boost of Hydrogen economy in the maritime sector.""


**Keywords:** Ship design,  safety engineering,  material & components requirements,  bunkering procedures,  risk assessment,  CFD simulation,  Digital Twin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'MObile Wideband Global Link sYstem'.

assistant: **Concept**

The proposed MObile Wideband GLobal Link sYstem MOWGLY aims at studying the implementation of DVB-S2/DVB-RCS standards for broadband access to users of collective mobile vehicles (aircrafts, trains and vessels). Existing mobile satellite communications systems offer only narrowband services or use proprietary solutions. The DVB-S2/DVB-RCS standard bears the potential for an efficient open approach for broadband access, however the effects of mobility have not yet been properly addressed. MOWGLY will investigate innovative solutions for satellite terminals in mobile environments, such as advanced medium access control for a crowd of passengers using the collective terminals with QoS control and networking technologies. Gathering leading actors of transportation and telecommunication industry as well as SMEs and Universities, the MOWGLY consortium will lever up this challenge. MOWGLY will value and extend large part of FP5 results and outcomes as well as several research activities conducted by ESA that have significantly contributed to consolidate the overall feasibility of our concept. MOWGLY will implement a demonstrator and validate both critical services and functions of satellite access system achieving a highest possible degree of re-use of existing or planned fixed broadband satellite access infrastructure. MOWGLY is targeting typical satellite markets by addressing large-scale of collective mobile environments. To reach a commercial deployment in 2008, MOWGLY will focus with its planned 24-month duration on economic and usage analysis, engineering studies and critical path validation. Trials of prototype communication chain allow validating the technological development, and to assess the offered services with expected customers and derive a business model. The o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'MOLECULAR BASIS OF ANTIBIOTIC TRANSLOCATION'.

assistant: **Innovation**

Multidrug resistant bacteria are now ubiquitous in both hospitals and the larger community. Drug-resistant pathogens are becoming increasingly pervasive, for example, the resurrection of tuberculosis provides one ominous example highlighting the risk associated with evolved drug resistance. Moreover, many pharmaceutical companies abandoned this field and no truly novel active antibacterial compounds are currently in clinical trials. Obviously we need new antibacterial molecules and maybe, novel strategies to develop antibiotics. The novel aspect here is to use state-in-the art techniques to quantify rate limiting steps of individual components involved antibiotic penetration and to validate them at the cellular level. Such a system biology approach identifies bottlenecks of existing antibiotics and might suggest novel antibiotic therapy. In Gram-negative bacteria, where influx and efflux systems located in the Outer Membrane represent a physical bottleneck for any antibiotic to reach a potential target. The aim is to investigate the molecular and cellular mechanisms at the basis of the influx and efflux processes and to teach scientists with different scientific background to go beyond theclassical faculty boarder. Bringing nanotechnology, physics, chemistry, computer modeling, pharmacology, microbiology together will facilitate the transfer of expertise acquired within the network in both academic and industry.To achieve these goals we propose a training program allowing young researcher to collaborate across traditional faculty boarder. Three partners from the private sector will actively participate, the first one is a SME developing unique nanodevices allowing high-throughput drug screening in the field of electrophysiology, the second one is engaged in developing n
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Identification, presentation and delivery of epitopes for development of novel vaccine for cytomegalovirus infections' (EPI-PEP-VAC) under Fifth Framework.

assistant: **Objectives**

The EPI-PEP-VAC consortium will use cutting-edge research and the most advanced technologies to elucidate the structural, biochemical and cellular basis of the immune response to exogenously delivered peptide epitopes, with the central objective of defining basic rules for the selection and optimisation of peptide vaccine candidates. The research will be focused on a pathogen of major health and socio-economical importance in the EU, namely human cytomegalovirus (HCMV). Novel strategies, technologies and read-out assays will be developed for peptide definition, modelling and screening to achieve optimal peptide performance. Animal models and ex-vivo models for follow-up will be developed and used for establishment of diagnostic tools and to optimise delivery system and immunization route of peptide vaccines.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Number Conserving Approaches to Bose-Einstein Condensates'.

assistant: **Concept**

Bose-Einstein condensation is the coalescence of a macroscopic number of boson atoms into the same quantum state. As such they are manifestations of a quantum effect on a macroscopic scale possessing many interesting and intriguing properties. Recent advances in experimental techniques have meant that many fundamental quantum phenomena can be explored through a Bose-Einstein condensate. When these systems are out-of-equilibrium they exhibit non-trivial dynamics that are highly dependent on quantum fluctuations around the condensed ground state. This project will use a number conserving approach to understand aspects of quantum fluctuations in out-of-equilibrium Bose-Einstein condensates in two cases that are theoretically and experimentally important: the effect of a non-zero temperature field and the dynamics at the interface in a mixture of condensates. It will then utilise these two cases to investigate the fundamental limit of metrology, using the Bose-Einstein condensate as the ‘test-bed’.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Galway laboratory for biomedical data mining' (2002-2006).

assistant: **Innovation**

This project will establish and develop a new interdisciplinary research lab for Data Mining in Biomedical Science in the National University of Ireland, Galway (NUIG). This is a new area of research expertise for the university. It will integrate and extend research being conducted by several separate research groups. Data mining involves a range of techniques that are concerned with extracting interesting knowledge from datasets that are typically large and unstructured.This knowledge can take the form of rules, patterns, structure or associations. To be interesting they must be non-obvious, comprehensible, meaningful and potentially informative or useful. Three biomedical application streams have been identified, each involving a different research group that has a specific need for data mining technologies:- Genomics: Identifying Patterns in Genomic Data;- Biophotonics: Analysis of Raman and Fluorescence Spectroscopy Data;- Biosensor Monitoring: Mining of Medical Telemetry Data.The project goal will be achieved through three principal work components:- Inward knowledge transfer, involving Experienced Researchers conducting research into data mining for each application stream- Embedding of knowledge in the university and dissemination to the wider community, through seminars, publications, and a new website of tools and technologies for biomedical data mining- Development of research collaborations with leading international research groups through research training secondments of by project participants.The scientific aim of this project is to establish a community of researchers in NUIG with an international profile in biomedical data mining and advance the state of the art. More broadly, it will contribute to NUIG's capacity to perform research, help to improve t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Disentangling processes controlling trophic connectivity between coastal and oceanic pelagic food webs' (PelCon) targeting Horizon Europe.

assistant: **Abstract**

The pelagic food web plays an important role in nutrient recycling and the production of food for commercially harvested species, especially in highly productive marine ecosystems. However, processes controlling the structure, function and connectivity of inshore-offshore pelagic food webs in these systems are far from understood, although it is well-known that food supply is a key factor driving these processes. Therefore, a better understanding of nutrient sources and dynamics, as well as trophic connections modulating the pelagic food web in these ecosystems is required to design effective conservation and management strategies in a changing ocean. While analytical techniques to quantify and track nutrient fluxes across the food web were previously lacking, recent advances in compound-specific stable isotope (CSIA) biogeochemistry provide a unique opportunity to assess and quantify trophic linkages between inshore-offshore pelagic food webs. The main aim of my proposal (acronym: PelCon) is to distinguish the input of different sources of production associated with inshore productive and offshore oligotrophic pelagic food webs in Hawai’i (oligotrophic North Pacific Subtropical Gyre) using stable isotopes of carbon (δ13C) and nitrogen (δ15N) in bulk tissues and individual amino acids (i.e. CSIA-AA). I also aim to develop indicators of trophic inshore-offshore connectivity based on stable isotope signatures that can be used to help predict global patterns in horizontal carbon and nitrogen flux in the coastal-ocean system. For this, I will compare the mechanisms coupling coastal-oceanic food webs between Hawai’i Island and a dynamic region in the NE Atlantic Ocean (Galicia, NW Spain) influenced by seasonal upwelling, for which I will apply the same isotopic techniques. I
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Genetic susceptibility for type 2 diabetes and obesity among immigrants in Europe - prevention and treatment'.

assistant: **Concept**

Immigrants in Western Europe have the highest prevalences of Type 2 Diabetes Melitus (T2DM) in the world, particularly those from the South-Asian countries after Pima Indians. This is a challenge to prevention and treatment in Europe today. Communities undergoing transitory lifestyle offer an ideal opportunity to study the patterns of genetics and its complex interplay with the lifestyles that may explain the increasing prevalence of obesity and T2DM in Europe and the rest of the world today. Obesity and T2DM may have some common genetic traits and endocrinological features but the pathophysiology responsible for the development of T2DM is yet to be established. The thrifty phenotype hypothesis introduced by Hales and Barker in 1992, may explain at least in part the increased prevalence of type 2 diabetes among immigrants in Europe, to-day. The understanding of the etiology and mechanism causing increased hyperglycaemia in this population will provide clues to more effective treatment and prevention of diabetes and obesity among immigrants. Furthermore, the information may help in understanding the T2DM in other populations, and thereby methods of treatment and prevention in general. But there is a need to organize cohesive efforts from various specialties of obesity and T2DM in genetics, bioinformatics, cell biology, clinical medicine, epidemiology, and prevention. Three Workshops will address genetics, epidemiology, prevention and treatment of obesity and T2DM. Reports from the Workshops and review articles will be made in order to present today's knowledge, and to identify needs for future research. Two Training Courses for new researchers and one International Conference will be held to summarise the comprehension of the acquired knowledge for the conception of a Ne
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Donor-Government Relations in Sub-Saharan Africa'.

assistant: **Objectives**

The proposed CIG will advance a high-impact, socially-relevant research agenda on the political consequences of new forms of development assistance. The project is of particular relevance to the EU and its member states given that European development agencies are dramatically increasing allocations to new aid modalities, such as direct subsidies to recipient countries’ national budgets. For instance, the 10th European Development Fund (EDF) allocates €13.5 billion or 44% of its portfolio to budget support in ACP countries.The proposed research investigates why some bilateral and multilateral aid donors are increasingly willing to fund aid programs that give recipient governments a large amount of control over where and how aid money is spent. The shift towards these aid modalities is interesting given that governance and institutional capacity in recipient countries remains poor and there is little evidence that such approaches are more effective. The project will generate original empirical data and theory on how foreign aid influences domestic political processes in recipient countries and how the logic of bargaining between donors and recipient governments can explain a variety of observable outcomes in development policy. While it is well known that aid dependence alters recipient governments’ incentives for cooperation and good governance, the bargaining process between donors and recipient governments remains poorly understood.In addition to generating fundamental scientific knowledge about donor-government relations, the findings of this study will be directly applicable to the design and implementation of more effective development assistance. As the PI comes from the US academic context, CIG support for her integration into the European research community will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Functional connectivity and the role of hub neurons in epilepsy' under Seventh Framework.

assistant: **Concept**

Determining the functional structure of neuronal networks has become an increasingly important tool to link functional and anatomical network structure. Recently, the analysis of functional network structure in the developing rodent hippocampus revealed the presence of highly connected, functional “hub neurons” with the ability to greatly influence synchronous network activity.   Additionally, these developmental hub neurons were shown to be early born neurons with an impressive anatomical structure which is conserved in adulthood.  Furthermore, computational modeling has predicted the importance of anatomical hub neurons in the development of synchronous epileptiform activity.   Here, we therefore propose to study the relationship between functional and anatomical network structure in a chronic model of temporal lobe epilepsy in order to link changes in network structure with the development of synchronous epileptiform neuronal dynamics.  Specifically, we plan to use multi-beam two-photon imaging to study acute slices under healthy and pathological conditions using the pilocarpine mouse model of temporal lobe epilepsy.  To achieve this goal, we propose two complimentary methods to determine the role of network structure and hub neurons in the development of pathological neuronal activity:  1) The construction and analysis of functional network structure from imaged calcium dynamics of the dentate gyrus in both healthy and pathological tissue, and 2) The direct observation of the impact of developmental hub neurons on network dynamics in epileptic tissue obtained from transgenic mice whose early born hub neurons have been labeled with GFP.