RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Spin Curves Enumeration' under Horizon Europe.

assistant: **Concept**

Enumerative geometry aims at counting geometric objects that satisfy specific algebraic conditions. The modern treatment of enumerative problems of curves has revealed deep connections between geometry, representation theory, and theoretical physics. These connections are established through the cohomology of moduli spaces of curves. The description of the structure of these cohomology groups is crucial in this modern perspective, and I will use spin curves to address this issue. Spin curves are refinements of curves carrying an extra sign, + or -, that enables the construction of new cohomology classes called spin classes. Spin classes carry rich algebraic structures that can be used to investigate enumerative problems. In the SpiCE project, I will study 2 open problems with this approach:Problem 1. Dubrovin defined Frobenius manifolds to study deformations of enumerative problems at a cohomological level. How can we describe singular Frobenius manifolds?Problem 2. How to enumerate curves in surfaces of general type?Spin curves have been extensively studied through techniques from several branches of mathematics. Yet, a general framework is missing. In SpiCE, I will combine my expertise in these fields to consider spin classes from a unified perspective. This novel approach will provide the means to prove structural results and enable significant progress on Problems 1&2. Problems 1&2 revolve around 3 fundamental families of spin classes and their interplay, which frame the 3 work packages (WP) of SpiCE and their respective goals:WP A. Witten’s class: prove a spin reconstruction theorem.WP B. Gromov-Witten theory: establish Virasoro constraints for spin curves.WP C. Strata of differentials: express spin Witten’s class via moduli spaces of differentials.The outcome is a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Understanding the roles of kainate receptors in the hippocampus'.

assistant: **Concept**

Kainate receptors (KARs) are often regarded as the last frontier of glutamate receptor research, since much less is known about their physiological roles compared with that of the other glutamate receptor subtypes. This field of research is very important not just because of the unique role that KARs play in neuronal function, including specific forms of synaptic plasticity, but because of the increasing evidence that KARs are involved in a plethora of brain diseases and that KAR antagonists are promising novel therapeutic targets. I propose to lead a highly multidisciplinary approach, in collaboration with colleagues at Bristol and strategic collaborators worldwide, to develop novel pharmacological and genetic tools, which will be rapidly disseminated to the neuroscience community. These tools will be used here to test hypotheses regarding functions of KARs in granule cells (GCs) in the dentate gyrus of the hippocampal formation, with a focus on mossy fibre long-term potentiation (LTP).  We propose four interrelated objectives: (i) to develop potent and selective antagonists for the GluK2 subunit of KARs, (ii) to generate GC specific knockouts of the five KAR subunits, by floxing GluK1-5 and crossing with a GC-specific Cre recombinase mouse line, (iii) to use these and existing tools in a combined pharmacological and genetic approach, to understand the functions of KARs at mossy fibre synapses in acute and organotypic hippocampal slices. A new development will be to record simultaneously from synaptically coupled GC-CA3 neuronal pairs and to image Ca2+ from participating mossy fibre boutons, (iv) to extend these investigations to the study of mossy fibre function, in particular LTP, in anaesthetised animals and to establish the function of mossy fibre LTP in hippocampu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Feasibility study for Multicursor - a non-contact sensor for curing quality control'.

assistant: **Concept**

Although manufacturing is moving towards digitalization and full automation, some industries, such as the furniture industry, are still heavily reliant on inefficient and outdated technologies. In particular, the furniture sector has been identified to lack any sort of automated solution for wood curing quality control, one of the critical manufacturing processes. Apart from causing a high defect rate, the absence of an inspection system creates a risk of manufacturing hundreds of thousands of pieces of furniture that are not adequately cured and potentially poisonous. This, in turn, leads to increased health risks and possible legal liabilities for the manufacturing company. To address the challenges, Factobotics, a Lithuanian robotics SME, has developed a novel solution– Multicursor. Multicursor is an intelligent non-contact polymerization quality system combining cutting-edge laser technology and machine learning models to provide a real-time response on wood surfaces curing level and quality. On the contrary to the existing solutions on the market, Multicursor is provided with a non-contact sensor, is easy to integrate into the process of manufacturing through, enabling automated quality control and data collection. Thanks to its competitive advantages the system will make measurement faster and allow zero defect manufacturing through real-time system monitoring and collection of valuable data. Multicursor is currently at TRL 6. The next step is moving on to TRL 7 that will require the introduction of the industry-grade prototype with further testing in the furniture production facilities. To ensure successful commercialization, in Phase 1 of SME Instrument, Factobotics intends to develop an elaborated feasibility study for Multicursor that is to include the finaliz
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Bioprinting of novel hydrogel structures for cartilage tissue engineering' (PRINTCART), addressing dissemination and exploitation.

assistant: **Impact**

Bioprinting is a young, promising but undeveloped area in tissue engineering. It refers to the automated fabrication of tissue engineering constructs with incorporated living cells. The particular advantages as compared to the manual cell seeding of prefabricated scaffolds are the abilities to mimic the cellular organisation of native tissues, and to upscale to (economically feasible) clinical application.The lack of suitable hydrogels is a major factor holding back the development of bioprinting. Our project aims to solve this problem by translating principles from other application fields to bioprinting technology, in order to develop new printable hydrogel formulations to advance this new field in tissue engineering. Our research objectives are (1) to advance bioprinting science and technology by applying, modifying and developing new hydrogel formulations to be used with a bioprinter, and (2) to use bioprinting to prepare cell-laden hydrogel constructs for articular cartilage tissue engineering, following a zonal approach.The outgoing phase will be performed at the Institute of Health and Biomedical Innovation at the Queensland University of Technology in Brisbane, Australia. Having a background in polymer chemistry and biomaterials, I will diversify my research by being trained in cell biology. The reintegration phase will take place at the University Medical Center Utrecht in the Netherlands, where I will be working in a clinical environment. In Australia, I will be learn from Professor Dietmar W. Hutmacher, a world leading expert in solid freeform fabrication in tissue engineering. This knowledge I will take back to the Netherlerlands to be adsorbed by the Orthopaedics group of Professor Wouter Dhert and Dr. Jos Malda.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Caveate: a novel tool to understand the role of the midbody during cytokinesis' under Fifth Framework.

assistant: **Concept**

The successful completion of cytokinesis depends on the regulated assembly of the midbody, a compact structure formedtransiently in the thread-like cytoplasmic bridge between two daughter cells. Several proteins have been described which localize to the midbody, many of which are also observed at the centrosome, but a complete survey of its composition is lacking largely impart to its transient nature. A molecular description of this structure may however help understand its dynamic formation and role in cytokinesis.The host lab has identified and cloned a novel caveolin termed Caveate" that in contrast to other caveolins is not membrane bound and has a diffuse localization in interphase but is recruited to the midbody during cytokinesis. The first part of the proposal aims to further characterize caveate biochemically and determine its binding partners as well as perform simultaneous imaging of YFP-caveate and CFP-microtubules/actin to investigate the dynamic assembly of the midbody. Interestingly however is the observation that GFP-caveate blocks cytokinesis at the midbody stage suggesting it has a possible role during final stage of cell separation. This will be investigated in cultured cells using RNA interference as well as through micro-injection of antibodies against caveate and any resulting phenotypes will be assessed. As GFP-caveate dominantly blocks midbody disassembly it provides the perfect reagent to "trap" this transient structure. Concurrently with the characterization of caveate we will use GFP-caveate as a tool to fluorescently label and enrich for midbodies to allow their purification for the first time. Midbody preparations will be subjected to two-dimensional gel electrophoresis and resulting proteins will be identified by mass spectrometry. Interes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Activities on drone integration and demonstration in VLL operations' (SAFEDRONE).

assistant: **Concept**

The scope of the SAFEDRONE project is to acquire practical experience in Very Low Level (VLL) operations where general aviation, state aviation and optionally piloted aircrafts and drones will share the airspace. It is important to highlight that this project will have a clear practical focus which primary activities will be innovation, integration, and especially, demonstrating activities with flight tests.The specific objectives of SAFEDRONE are the following: 1. Demonstrate how to integrate general aviation, state aviation, optionally piloted aircrafts and drones into non-segregated airspace in a multi-aircraft and manned flight environment, in order to explore the feasibility of U-Space vision by 2019.2. Perform a large number of demonstrations in order to accumulate evidences and experience about the required services and procedures necessary to operate drones in a safe, efficient and secure way within U-Space.3. Validate proof of concept implementations of a large variety of U-Space services and procedures.4. Provide evidences to EASA and National Aviation Authorities to reinforce the safe integration of drones under U-Space for the different drone categories. Also, the lessons learnt and the technologies used during the project will be proposed to the different standardization bodies.5. Coordination with the recently approved SESAR-RPAS projects in order to align the demonstrations with the CONOPS and technological developments of these projects. 6. Increase the awareness of the advances in U-Space within Europe through the dissemination of the obtained results. Finally, SAFEDRONE consortium is formed by 2 private companies (INDRA and UNIFLY), 2 government-owned companies (IAI and ENAIRE), two aeronautical research centres (CATEC and CRIDA) and one university (Un
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Bridging the world of fungi and dementia' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Alzheimer’s disease is the most common form of dementia which seriously interferes with the daily life of millions of people. People suffering from Alzheimer’s disease show the accumulation of two misfolded proteins in the nerve cells of their brains – amyloid plaques and tau tangles. Although many aspects of the Alzheimer’s disease pattern are well-established, only little is known about the onset, development and progression of this disease. Thus, early detection, including diagnosis before symptoms become visible, is still not possible yet. Furthermore, the development of drugs designed to slow down or even prevent Alzheimer’s disease progression is very difficult and tedious.In the envisaged project, a microorganism, the filamentous fungus Aspergillus niger, will be used to study the onset and development of Alzheimer’s disease. The presence of misfolded proteins in this microorganism provokes a cellular reaction that shows many parallels to what is known from nerve cells. It seems that both man and fungus use similar defense strategies to detect and get rid of dangerous misfolded proteins. This makes A. niger very appealing for use as a model system to explore in utmost detail the origin and temporal progression of Alzheimer’s disease. As it is a fast-growing and easy genetically tractable organism, respective analyses can be performed very cost and time effective, something which is not feasible when working with human cell models.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Cost-effective  High-efficiency Smart Steam Boiler of Low Emission technology' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

With EcoVapor, we offer a smart steam boiler that will make steam production a very cost-effective (ca. 30-50% cheaper than typical 3-pass boilers of low NOx emissions), energy-efficient (up to 95% overall), smart (custom-designed based on specific needs for the industry which operates at different powers within a large modulation range (5-100%)), and environmentally friendly alternative (only 80mgNOx/kWh emissions able to comply with the most stringent regulations) to appeal to market segments that want to foster the uptake of new steam-generating technologies to reduce energy bills, optimise energy consumption, and reduce NOx emissions. Our company, ICI Caldaie, has partnered with Burnertech - a UK based engineering company specialised in design and manufacturing of tailored solutions for burner design – Troll System - an Italian company with more than 20 years expertise in custom-designed products of the electronic market - and CTIC-CITA - a Spanish cluster of companies of the F&B sector, to exploit €69.44 million accumulated revenues (by 2022) business opportunity. EcoVapor has been developed integrating a low NOx pre-mix burner developed by ICI based on the combustion head of Burnertech (patent application: WO2014167270 (A1)), and an e-term® PCB control electronics from Troll.We plan to penetrate initially the EU F&B industry by mid-2018 in countries coinciding with ICI highest volume of sales (Italy, Spain, UK, France, Poland, and Romania), and then, other industries starting from 2019 (i.e. textile, tanning, chemical, and pharmaceutical) in EU and non-EU countries we already have a consolidated presence (Serbia, Ukraine, Russia, and Kazakhstan) along with US and Canada by 2020, through direct contact of our current sales force.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Galaxy Evolution: Solving the hierarchy problem with powerful AGN' (2007-2013) targeting Seventh Framework.

assistant: **Abstract**

Understanding the physical processes that shaped galaxies in the Universe is a key goal of astrophysics. However, we face a fundamental problem between the disciplines of theory and observations in explaining the characteristics of massive galaxies (“The Hierarchy Problem”). Theoretical models suggest that galaxies evolve though hierarchical mergers in a gradual assembly of galaxies which is thought to induce contemporary starburst activity from the interacting gas and dust.  However, we also know early-type galaxies are characterized by their deficiency in the large quantities of cool dust and gas associated with mergers and needed for star formation. We are then left with the following fundamental problem: In the context of galaxy evolution through hierarchical mergers, what inhibits star formation and galaxy growth in massive, early-type galaxies?A popular, but still unproven, way of solving this question is by ‘AGN feedback’. In galaxy mergers, large amounts of dust and gas maybe funneled down towards the galactic cores triggering an AGN.  In turn the AGN can then produce intense nuclear emission and collimated jets that will influence the AGN galaxies local environments, star formation histories through excitation and ionization of the Inter Stellar Medium (ISM).The fact that AGN may play such a critical role in galaxy evolution is not reflected in our understanding of these objects. To address this problem, in close collaboration with researchers at IAS, I have developed a science program which will allow us together to address the key question of the triggering mechanism for AGN and the star formation evolution of the host galaxy, using data from the latest state of the art observatories available to us (Herschel, IRAM, ATCA). Due to the uniqueness of the data av
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Bioremediation Euro-Conference: Contaminated soils, surface and groundwater bodies; Biodegradation of chlorinated and recalcitrant compounds' (1998-2002) under Fifth Framework.

assistant: **Objectives**

The remediation of sites contaminated by hazardous substances is a major environmental concern throughout the world. Bioremediation is a developing technology that uses micro-organisms to degrade contaminants into less toxic or non-toxic compounds. At a time when more traditional remediation technologies are proving to be slow and expensive, bioremediation has become a popular and attractive alternative.The purpose of the two planned Euro-Conferences on Bioremediation is to bring together scientists, engineers and other environmental professionals from all over Europe to present their findings and discuss future trends and directions for the restoration of contaminated sites and marine environments. High-quality, original articles or invited scientific reviews will deal with laboratory experiments and/or field application of technologies for assessment and bioremediation of aquifer, soil, and marine environments contaminated with pollutants such as MTBE, PCBs/Dioxins, Pesticides/Herbicides, Explosives/nitroaromatics, PAHs and Perchlorates.Particular technologies will include: Intrinsic bioremediation, Air sparging and related technologies, Bioslurping, Bioventing, Anaerobic and aerobic degradation, Phytoremediation, Bioreactors, Emerging and innovative technologies, Bioaugmentation, Biodegradation of recalcitrant and chlorinated solvents as well as the monitoring of bioremediation process performance.Although both Euro-Conferences will cover recent advances in bioremediation, the focus / theme of each conference will be different. Bioremediation-1will take place in late summer of 2001 and will focus on the technologies for in-situ and on-side (ex-situ) remediation of contaminated soils, surface and groundwater bodies (including contaminated sediments and refinery sludge