RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Translational METabolomics for NEurodegenerative Diseases dIAgnosis and prognosis' (METNEDIA).

assistant: **Concept**

The prevalence of neurodegenerative disorders, including Alzheimer’s disease, Parkinson’s disease, Amyotrophic lateral sclerosis and frontotemporal dementia, continues to rise, partly due to increasing life expectancy. The diagnosis of these disorders remains a significant challenge due to overlapping symptoms, delayed recognition of early symptoms often mistaken for normal aging, and variability in symptom presentation across patients.METNEDIA will tackle these challenges by proposing a new framework for the development of a diagnostic tool. METNEDIA will utilize metabolomic analysis and artificial intelligence to develop a diagnostic tool for the diagnosis of neurodegenerative diseases. A discovery phase will be initially performed using untargeted metabolomic approaches to identify most relevant biomarkers. The project will then develop of a diagnostic kit based on mass spectrometry and artificial intelligence for the diagnosis of widely diffuse neurodegenerative diseases. A multicenter validation of the kit will be also performed. Neurotoxic evaluation of molecules identified as relevant for each disease will be evaluated in vitro. Finally, bioinformatic and machine learning will be used to gaining insight on the biology of neurodegenerative disorders using in vitro and in vivo data.


**Keywords:** Diagnostic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Train interior passive safety for Europe' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Train crash events can be basically depicted into two phases:i) The primary collision, where the initial kinetic energy is progressively dissipated by means of plastic structural deformation. In this phase occupant compartment integrity and acceptable vehicle acceleration levels (crash pulses) are the most important design requirements to be considered.ii) The secondary collision, where the occupant will be subject to a great variety of potentially harmful occupant/interior or occupant/occupant contacts. Design requirements must involve the aspects of interior layouts, acceptable severity levels and biomechanical response to vehicle crash pulses.This new interior passive safety platform will provide tangible and commercially viable solutions and a system s approach to methodically reduce injuries and fatalities by combining and exploiting in a cost efficient and optimised manner the already well matured railway structural crashworthiness (closely linked with primary collisions events), with injury biomechanics, directly associated with secondary collisions. The friendliness of the compartment interior is a major design issue and its treatment will complete the framework of railway passive safety. The purpose of the SAFEINTERIORS project is to provide the different railway stakeholders with a currently missing platform capable of assessing interoperability of all present and future interior rail vehicle layouts.The proposed framework will address design requirements and assess new interior solutions following advanced state-of-art interior designs, representative layouts, a range of suitable crash pulses and new test and validation procedures suitable to the rail industry. The use of new materials will be fully exploited to improve the occupant/furniture con tact charact
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Axonal regeneration, plasticity & stem cells' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

This is a multi-disciplinary training programme focussed on the experimental and clinical problems associated with axonal damage and repair in the central nervous system. This is a central feature of a wide variety of disorders of the CNS. Future advances in this area depend on training a cohort of young researches with multiple skills. The programme encompasses ten academic and two commercial organisations. Each student will be trained in a variety of theoretical and technical approaches, based on the complementary expertise of the collaborating partners. In addition, there will be a strong emphasis on the commercial exploitation and development of potential new therapies. The individual projects are strongly cross-disciplinary, and a series of workshops, seminars and online tutorials will ensure the collective resources of each participant being available to each student. These will foster a sense of collegiality amongst the students themselves, and knowledge of the work going on in the labs of the consortium. The programme will have a common organisation strategy, with a balance between control by the coordinators and delegation to individual laboratories. The topics themselves range from studies on the molecular biology of gene expression during axonal damage and regeneration, through cellular approaches for rescuing axons, artificial systems for growing and studying axons in vitro, the use of stem cells as regenerative procedures, advanced imaging techniques for assessing axonal integrity, studies on ways to alter axonal plasticity, pharmacological approaches to preventing or restoring axonal damage, new surgical and experimental methods for studying axonal structure and function, tests of recovery (including both physiological and behavioural techniques) and the c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Safeguarding Carbon and Biodiversity across European Forest Ecosystems through Multi-actor Innovation' in the context of a Horizon Europe call.

assistant: **Objectives**

Restoring and protecting natural and semi-natural forest ecosystems can play a vital role in creating climate-neutral and sustainable societies. Using advanced technologies and methodologies, FORbEST will devise solutions that improve forest function and harness the potential for healthy forested ecosystems as a means of achieving EU biodiversity and climate objectives. We will work with management and conservation practices across five key EU biogeographical regions and one non-EU tropical region, to understand the impact of past and current governance and create shared roadmaps toward sustainable futures. Using a strong complement of technologies including advanced remote sensing, artificial intelligence, citizen science, participatory action research and ecoacoustic methods, we will unlock powerful, comprehensive monitoring regimes of forest habitats, which will enable a better understanding of their resilience and functionality. FORbBEST understands and embraces the complex nature of the socio-ecological systems that characterize forested landscapes. Integrated socio-ecological modelling will enable us to identify win-win forest management practices that support forest protection and restoration, and community co-migration. Our research is grounded in a transdisciplinary approach, using participatory Living Labs to steer our engaged, knowledge-intensive research workshops across the project. These platforms will empower diverse local stakeholders to collectively imagine, iterate, and co-design new paths and best practices for forest management. Robust stakeholder engagement will disseminate tailor-made information on project results, which will, for example, encourage better forest protection and restoration via economic incentives and legal mechanisms. FORbEST will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Elucidating the molecular basis of fruit resistance to desiccation: The cuticle as a key factor' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Water stress is a key environmental factor that causes important quality and economical losses before and after fruit harvest. As water depletion is becoming increasingly problematic, improving water efficiency and tolerance of plants to dehydration is a priority of the European Union, as reflected in the societal challenge of Climate action, environment and resource efficiency. Likewise, food waste reduction is another key issue in the framework of Horizon 2020, as described in Food security and sustainable agriculture and forestry challenge. Indeed, a large proportion of fresh produce is wasted during postharvest (25-50%) of horticultural crops, which is largely caused by dehydration. Therefore, this project deals with the urgent need of understanding factors influencing water loss to develop innovative solutions geared to saving water and reducing food waste. Based on the idea that cuticular waxes are critical for limiting water loss from fruit, and thus for resisting desiccation and spoilage, we propose to uncover the structural and regulatory pathways that mediate its biosynthesis, transport and assembly in response to drought stress through a multidisciplinary approach. Thus, SEM and TEM microscopy, GC/MS, as well as up-to-date technologies, such as Laser Capture Microdissection (LCM) and RNA sequencing, will be used. Tomato and citrus fruit will be selected as model systems to address this poorly understood area of plant biochemistry, physiology and molecular biology. The availability of mutants of both fruits, as well as the application of stress-related hormones during postharvest, will allow comparative surveys to better understand the regulation of these processes. The outcomes of this proposal will represent a major advance in the understanding of the crossl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Asymptotic Symmetries: from Concepts to Observations' (SymCO).

assistant: **Concept**

At its core, Nature is described by gauge systems such as electrodynamics and gravitation. Such theories are written in terms of redundant quantum fields, but it was recently realized that some of these redundancies are, in fact, genuine symmetries. The corresponding transformations are known as asymptotic symmetries, a prominent example of which is the intriguing Bondi-Metzner-Sachs (BMS) group relevant to gravitational radiation. Accordingly, the purpose of this project is to study asymptotic symmetries along three axes. Firstly, look for their experimental signatures, such as memory effects or Berry phases. The latter are uncharted territory, so many of their aspects remain to be clarified; besides, their scope goes well beyond high-energy physics, as analogous phases exist in shallow water dynamics. Secondly, address the conceptual issue of field-dependent central charges occurring in asymptotic symmetry algebras of various gauge systems; this feature is radically new for symmetries in Nature, and has the potential to overturn many of our preconceptions about symmetries in general. Thirdly, relate representations of asymptotic symmetry algebras to Faddeev-Kulish dressing; this reformulation would open the door to countless applications and to a conceptual leap in our understanding of both particles physics and quantum gravity.


**Keywords:** Symmetries,  Gravitation,  Holography,  Gauge theories,  Infrared dressing,  Stokes drift
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'leArning and robuSt deciSIon SupporT systems for agile mANufacTuring environments' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

With a multidisciplinary consortium combining key skills in AI, manufacturing, edge computing and robotics, ASSISTANT aims to create intelligent digital twins through the joint use of machine learning (ML), optimization, simulation and domain models. The resulting tools permit to design and operate complex collaborative and reconfigurable production systems based on data collected from various sources such as IoT devices. ASSISTANT targets a significant increase in flexibility and reactivity, products/processes quality, and in robustness of manufacturing systems, by integrating human and machine intelligence in a sustainable learning relationship.ASSISTANT provides decision makers with generative design based software for all manufacturing decisions. Rather than writing ad hoc code for each manufacturing sector, it provides a set of intelligent digital twins that self adapt to the manufacturing environment. It promote a methodology that enhances generative design with learning aspects of AI thanks to the data available in manufacturing. ASSISTANT aims to synthesize predictive/prescriptive models adjusted to the shop floor for each decision levels. Digital twins will be used as oracles by ML in order to converge towards models in phase with reality. This means that rather than writing specific code to cover a restricted set of goals/scenarios/hypotheses for a manufacturing system and a decision level, ASSISTANT will aim at learning models that can be used by standard optimization libraries. In this context, ML is used to predict parameter values, characterize parameters uncertainty, and acquire physical constraints. ASSISTANT will experiment this methodology on a significant panel of use cases selected for their relevance in the current context of the digital transformat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Building Relationships and Interactions to Develop GMES for European Security'.

assistant: **Innovation**

Based on the assumption of (i) the involvement of the EUSC in the Security Dimension of GMES and (ii) the need to support the definition of the cooperation between GMES & EUSC (supported by the EUSC Board) and a structured dialogue among stakeholders, the BRIDGES project intends to:•Perform an in-depth analysis and further define the EUSC’s possible role(s) in GMES•Identify the financial and legal consequences of the potential implementation of these roles on the basis of several options•Analyse existing governance models in the Space domain in order to provide inputs and recommendations for the definition of the governance scenario that will be identified in the course of the project•Identify scenarios and implementation options, taking into account the current state of GMES and the EUSC’s role, for:-A coordinated approach to space data access in the Security field.-GMES’s potential contribution to CFSP/ESDP, in an operational capacity.•Propose governance options and a roadmap for the implementation of the scenarios identified•Evaluate the benefits for GMES and provide an impact assessmentAlternative scenarios will also be explored in order to ensure a wider approach such as operational coordination for data access by ESA or EUMETSAT or cooperative approach between several entities with complementary roles.The strategy of BRIDGES is based on a constant dialogue with relevant institutional decision-making stakeholders (e.g. EEAS, CMPD, EDA, ESA, EC, EU Parliament, Member States, etc.) and user organisations, supported by the industry’s insight on service delivery schemes and associated costs.This dialogue is expected to significantly raise stakeholders’ awareness of the synergies between GMES and CFSP/ESDP areas and to provide food for thought for the project deliverabl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Preparation and catalitic activity of coordinatively unsaturated carbene ruthenium complexes' (1994-1998).

assistant: **Innovation**

Research objectives and content Coordinatively unsaturated carbeneruthenium complexes have been the subject of intense research due to their high activity as catalysts for olefin metathesis. These complexes have been prepared using cyclopropenes or diazoalkanes as carbene-generating reagents. A new and versaltile synthetic route to such kind of complexes has been recently developed at Prof. Werner's group. This method involves the use of terminal alkynes and we consider it much more convenient since terminal alkynes are more easily accesible than cyclopropenes or diazoalkanes. Taking advantage of this new method, the research work will focus on the synthesis of new ruthenium catalysts and the study of their catalytic activity. The development of new well defined catalysts and their use in ring opening methatesis polimerization would provide access to new polymers with controlled structure and properties. The main objectives of the research work will be the following: 1. Improvement of the synthesis of carbeneruthenium complexes from commercial ruthenium trichloride as precursor. A more simple and direct method would be important for catalytic reactions on a large scale. 2. 'Fine-tuning' of the catalytic activity of the ruthenium complexes by variation and/or replacement of the different ligands attached to ruthenium. 3. Preparation and study of the catalytic activity of analogous osmium complexes. 4. Mechanistic studies of the catalytic reactions. Training content (objective, benefit and expected impact) This project involves: I) synthesis of new complexes, 2) characterization of the complexes obtained by spectroscopic methods and X-ray crystallography, 3) design and development of new catalytical processes, 4) mechanistic studies, and 5) adaptation of research objectiv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Electronic correlation in pristine and doped graphene layers'.

assistant: **Objectives**

Since the discovery of two–dimensional and meta–stable graphene sheets, the recent years have witnessed a dramatic increase in the research dedicated to explore its physical properties. This can be attributed to the two following reasons. First, graphene allows one to address basic questions of quantum mechanics such as relativistic Dirac fermions or the Klein paradoxon in a simple condensed–matter experiment. Second, the nanometer size, the scalability and room–temperature ballistic transport properties make graphene a promising candidate for future nanoelectronic devices with high electronic mobilities and an ideal material for spintronics. In this proposal, the spectroscopic investigation of functionalized mono– and few–layered graphene (FLG) is suggested. The samples are already available as graphene layers grown by precipitation on SiC and by chemical vapour deposition on metal (111) surfaces and as graphite intercalation compounds (GICs), consisting of stacked layers of doped graphene sheets. Their electronic, vibronic and optical properties as a function of functionalization will be investigated by optical spectroscopies, photoemission and electron energy loss. We utilize a combined experimental and theoretical approach in order to gain a deep understanding of graphene physics. Particular emphasis will be paid to electronic correlation effects and how they contribute to the recently discovered exotic properties of graphene. Our multi-disciplinary approach ensures that the results obtained will not only contribute to the fundamental understanding of correlation effects but also yield valuable input for device physics of graphene.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Origins of the Vernacular Mode. Regional Identities and European Networks in Late Medieval Europe' (OVERMODE).

assistant: **Concept**

Based on comparative studies and contextualisations of European vernacular religious literatures, this project aims at new insights about the dynamics of regional ( vernacular ) identity formation in the 14th and 15th centuries. The investigation will focus on intellectual elites linked in close, supra-regional networks, who gradually introduced the  vernacular mode  in the dominant theological discourse; at the same time, they increased the symbolical charge of the vernacular languages. The core period studied in the project will be the second half of the 14th century, a period in which new forms of institutionalisation and discursive orientation of  ecclesiastic and lay powers began to take shape, and directions were taken that should prove decisive for further development. At the time, Prague was the political and intellectual centre of the Holy Roman Empire, but its international impact is grossly understudied. The project will therefore mainly deal with the rich and little-known production of Czech religious literature. It sets out to reconstruct the personal networks engaged in the creation, translation and propagation of vernacular religious literature, and in the formation of textual communities and cultural identities at the treshold from Latin to the vernaculars.