RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Tracing connectivity via ceramic technology in riverine environment of the Middle Danube Region during the Ottoman period' (DANUBE).

assistant: **Concept**

DANUBE aims to study cultural connectivity among potters in riverine environment of the Middle Danube Region during the 16th-17th centuries, which is a phenomenon of central importance for an archaeological interpretation of cultural change in Central Europe initiated with the Ottoman expansion. This interdisciplinary study combines archaeological and scientific analyses of common pottery with an anthropological theory on technology and written sources of the Ottoman period to reconstruct the ceramic production technology and means of knowledge transmission along the Danube-Sava-Drava rivers. Common pottery included in DANUBE is part of six largely unstudied archaeological collections from Serbia and Croatia, and this project aims to highlight existing potentials of the Middle Danube Region for archaeological studies of the post-medieval period. Focusing on pottery consumed in riverine settlements after the Ottoman conquest, the project explores links between ceramic morphology, technology and cultural connectivity. DANUBE is the first study of riverine connectivity in Post-Medieval Archaeology of Central Europe. Although DANUBE deals with a specific region, it can be used as an exemplar for addressing broader cross-cultural and methodological questions regarding the role of rivers for networks of knowledge exchange and connectivity in the context of large-scale migrations, military pressure and cultural change. The project introduces the regional-scale approach to ceramic studies in the Middle Danube Region and goes beyond ceramic morphology to explore human interactions along large rivers of Central Europe. DANUBE benefits from the applicant’s sound research experience crosscutting archaeological and scientific studies of Ottoman ceramics in Southeastern Europe, combi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Climate Positive Drying System for Coffee Industries using a highly disruptive Pyrolysis Technology'.

assistant: **Innovation**

PYROTECH is based on a highly disruptive pyrolysis technology as a heating source for drying coffee cherries and makes it possible to produce biochar (a fertilizer used in coffee agriculture). It will displace the market’s “dry methods” for processing coffee, which involves sun drying or the use of heat coming from a conventional burner, which produces heavy smoke, environmental pollution, and lung diseases as well as negatively affecting the quality of coffee cherries quality and resulting in black colouring. PYROTECH is four to ten times cheaper than other pyrolysis systems. It will generate more than 6,5 million euros of additional income for European coffee companies and will eliminate more than 18.000 tonnes of C02 emissions in the first three years due to the carbon sequestration potential of coffee husk used and biochar produced. Currently, more than 9,5 million tonnes of green coffee beans are processed annually, from which 4,8 million tonnes are produced using the dry method. Taking into account the market size, market distribution and current interest of our potential clients, PYROTECH will cover after five years of commercialization, 18% of the total amount of pyrolysis machines needed to dry the coffee cherries. Coffee buyers will require farmers to use PYROTECH as a result of the increased quality of the product, the decrease in the selling price and the improved health and safety conditions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Global Neutron Scientists' (GNeuS), addressing dissemination and exploitation.

assistant: **Impact**

Research with neutrons, with its interdisciplinary approach, is indispensable for modern science. Taking into consideration tremendous changes in the European neutron landscape and assuming responsibility for sustainability, the neutron community is nowadays facing an important task to ensure long-term perspectives, that essentially depend on its ability to create a new generation of innovative highly-skilled researchers. To tackle this challenge, Forschungszentrum Juelich (FZJ), Technical University Munich (TUM) and Helmholtz Zentrum Geesthacht (HZG), partners at the Heinz-Maier-Leibnitz Zentrum (MLZ), will train young neutron scientists through the establishment of a well-structured post-doctoral research programme with a strong interdisciplinary and intersectoral approach and global outreach. Responding to the recommendation of the ESFRI Innovation Working Group Report (March 2016), ""for moving into the era of global thinking for neutron sources"", the Global Neutron Scientists (GNeuS) programme will be implemented as a global network in cooperation with world-leading neutron sources aiming to create a community of neutron experts able to use future facilities such as the European Spallation Source (ESS). In order to maximize the outcome for fellows, the three MLZ partners will join forces with 19 partner organisations from around the world representing research, academia and industry. The GNeuS programme will provide the best conditions for training of the next generation of  neutron researchers to solving the grand challenges facing mankind in areas such as environment, energy, key technologies and life sciences. This 5-year programme will offer a total of 45 fellowships each with a duration of 24 months. The MLZ-partners FZJ, TUM and HZG will act as hiring organi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Miniaturised Robotic systems for holistic in-situ Repair and maintenance works in restrained and hazardous environments'.

assistant: **Objectives**

MiRoR aims to develop a fundamentally novel concept of a Miniaturised Robotic Machine (Mini-RoboMach) system, that equipped with intelligence-driven and autonomous abilities, will be demonstrated for holistic in-situ repair and maintenance of large and/or intricate installations.This will be done via the following research steps:-Develop a novel concept of Mini-RoboMach, with unique complementary miniature systems: (1) novel “free-leg hexapod” (i.e. without base platform) for providing both “walking” and 6-axis processing capability; (2) an original stiffness-controlled flexible-arm robot for enabling “snaking” and 6-axis light processing ability. The complementarily means that a hybrid configuration of Mini-RoboMach, i.e. “walk & snake-in” can be utilised.-Develop MiRoR intelligent controller equipped with following key abilities:Self-positioning: enable walk and/or snake navigations to/from work and calibration of end-effectors on required features;Reasoning: decide on methods of accessing the working area (walking and/or snaking-in mode) while learning from these experiences.Planning: schedule task successions and optimise Mini-RoboMach path in reference to intervention on different places within the installationAdaptation: modify the parameters of treatment procedures for developing a self-protection ability of Mini-RoboMach in case it encounters harmful/unfavourable conditions.-Develop a unique virtual test bench for the hardware (e.g. Mini-RoboMach) and software (intelligent controller) of MiRoR so that its robustness and capability to work unsupervised within required harsh/remote workspaces can pre-assessed and corrected before its effective utilisation.-Demonstrate MiRoR by performing in-situ holistic repair/maintenance works (e.g. inspection and processing – m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Respond to Emerging Dissensus: SuPranational Instruments and Norms of European democracy'.

assistant: **Objectives**

RED-SPINEL stands for 'Respond to Emerging Dissensus: SuPranational Instruments and Norms of European democracy'. It is an interdisciplinary and intersectoral Research and Innovation Action bringing together 11 partner organisations from 8 European countries. It will jointly analyse the changing nature of dissensus surrounding liberal democracy and its implications for EU supranational policy instruments. RED-SPINEL will unpack the inter-connected drivers of contemporary dissensus surrounding liberal democracy. Its findings will be rooted in theoretical innovation and original empirical analyses. Its concept-building effort centered on the notion of 'dissensus' will explore how contemporary dissensus surrounding liberal democracy differs from previous debates and which more fundamental questions it raises about future democratic practices and the rule of law. Ultimately, RED-SPINEL will provide a typology of said dissensus, map the principal actors of the dissensus in Europe and unpack its two underlying drivers - i.e., heightened internal contestation over liberal democracy and external competition from alternative illiberal models. Empirically, RED-SPINEL will focus on the key policy instruments and legal mechanisms shaping the EU's efforts in support of democracy and the rule of law. The studied instruments include the EU rule of law toolbox, the neighborhood and accession instruments, the European semester, fundamental rights and judicial instruments, as well as citizen participation platforms.Furthermore, through a series of stakeholder events, RED-SPINEL will flesh out the implications of its findings for public policy stakeholders (i.e. legal professionals, policymakers, European youth) as well as EU instruments aimed at responding to said dissensus. The project
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Distributed Environmental Disaster Information and Control System'.

assistant: **Objectives**

DEDICS is a telematics tool to help prevent and fight a wide range of environmental disasters by supporting the monitoring and control of those in charge of intervention. Early detection for rapid response and simulation for anticipating it are among services with an interactive communication core to link users in offices and on the field. Geared to regional intervention, DEDICS will be tested on forest fires to assist fire control managers, local authorities, and prevention research agencies. It will also boost cooperation by assessing common needs, evaluating solutions and organising demonstrations (involving users from six EU countries)DEDICS is a telematics tool designed to facilitate the management of environmental disasters by providing users with a set of functions to support monitoring, control and decision-making. The system is composed of elements designed to provide key information to the users: early detection for fast response, simulation for preparing types of intervention, data server for sharing experience, and building up an information asset for post-analysis of disasters. These services use an interactive communication kernel, which links all types of users in headquarters, offices and the in field of operations.As most environmental disasters are on a regional scale, DEDICS is a regional system. It is designed to be adapted to a wide range of such situations. Its application will be tested on forest fires, which constitute one of the most frequent and difficult kinds of environmental disasters in Europe.DEDICS concerns three categories of users who share common interests and needs:- fire managers, involved in prevention and fighting of forest fires- local authorities, responsible for land management, resource allocation and information to the public-
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'A novel, first-in-its-kind, aptamer-based LYTACs to address the unmet clinical need of diabetic wounds.' (APTADEGRAD).

assistant: **Innovation**

Diabetic foot ulcers (DFUs) a major complication of diabetes, occur in ~25% of patients, with a five-year recurrence rate of ~65% . DFUs often end in hospitalization, with limb amputations in up to 60% of cases . DFU related mortality is 5% within twelve months, rising to 42% after five years. Despite high prevalence and its major impact on the quality of life, no effective treatment has been approved, so DFU remain a highly unmet clinical condition.APTADEGRAD aims at obtaining in vivo proof-of-concept for a novel, first-in-class therapy using aptamer-based Lysosome Targeted Chimeras (LYTACs) to heal diabetic foot ulcers (DFUs). These LYTACs will target IL-1β, its receptor IL-1R1, and MMP-9 for degradation, proteins known to play a key role in impaired healing in diabetic wounds. Out hypothesis is that a) aptamer-based LYTACs MoA, may offer the potential to deliver a controlled, dose-dependent reduction of MMP9, IL-1b and its receptor IL-1R1, moderating the excessive DFU inflammatory response, while maintaining biologically beneficial levels of these proteins to promote healing and prevent infection; b) the simultaneous targeting of these relevant proteins will produce a synergetic effect in the inflammation cascade, providing superior efficacy outcomes.Should the main objective of the project is achieved (i.e. show efficacy in animal models of DFU), we would be showing for the first time a potential therapy based on LYTACs, in this case in the context of diabetic ulcers, with potential applications in other types of chronic wound or immune pathologies. In addition to efficacy data, we will be gathering essential knowledge about LYTACs (toxicity, efficacy, mechanism of action, differences with other approaches such as blocking or inhibition which are essential for succe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Structure and interrelationship of closed ideals of operators on banach spaces'.

assistant: **Objectives**

Research objectives and content The project aims at creating new insight into the structure of the Banach algebra B(X) of all operators in a Banach space X and certain closed ideals in B(X). The focus is in particular on the interplay between the specific properties of the Banach space X and the structure of these Banach algebras. The research concentrates on two themes: 1. Let A be one of the above-mentioned Banach algebras. When is A amenable? If A is not amenable, then I wish to investigate whether A satisfies certain weaker conditions. 2. When does a certain short exact sequence split? If it splits, can the splitting homomorphism always be chosen to be continuous? The main tool in these studies is K-theory. I plan to compute the K-groups of Banach algebras of the above-mentioned kind, and I wish to determine which pairs of abelian groups that arise as (Ko(B(X)),K1(B(X))) for some Banach space X. Training content (objective, benefit and expected impact) I will be trained as a researcher in pure mathematics through my cooperation with experienced mathematicians (notably H.G. Dales and the team in functional analysis) at the University of Leeds and its neighbouring universities and through my participation in seminars on functional analysis and K-theory. Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Direct co-processing of CO2 and water to sustainable multicarbon energy products in novel photocatalytic reactor ​' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Solar fuels, produced via solar driven CO2 and water conversion can contribute to drastically reducing GHG emissions and implement a man-made carbon-cycle complementing the natural-one, deploying the circular economy strategy. However, at present, significant improvement in the photocatalysts and reactor technology is required for solar fuels’ production to become technically feasible, scalable, affordable, secure, sustainable, and efficient. DESIRED is a high-risk high-return project, focused on establishing the technological feasibility and sustainability of a novel fuel production system – the DESIRED system – for direct coprocessing of, possibly atmospheric, CO2 and water to produce multi-carbon (C2+) energy-rich products using sunlight as primary energy source. The DESIRED system will produce C2+ solar fuels (without overlooking C1 species such as methanol or methane) by direct coprocessing of CO2 and water using novel and recyclable hybrid photo-electrocatalysts, supported on frustules or zeolites, in an innovative photoreactor design applying, for the first time, oscillatory flow principles, combined with direct light irradiation.  With regards to applications, DESIRED will focus on products, which, by 2050, would be used per se or as intermediates to produce drop-in fuels for sectors where direct shift to batteries or H2 is not a technically and cost-efficient option (e.g. aviation). Knowledge of the economic affordability, environmental benefits, and social acceptability of this approach will be investigated. DESIRED promotes an interdisciplinary approach to research and innovation undertaken by a consortium of 7 European partners and complemented by cross-cutting activities including modelling, process simulation, sustainability, and techno-economic assessment
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Identification of Transiently Formed Immune-Endogenous Neural Stem Cell Niches in Spinal Cord Injury' (SCIENSC) under Horizon Europe.

assistant: **Objectives**

Despite endogenous neural stem cells (eNSCs) being present in the adult mammalian central nervous system (CNS), their neuronal potential upon injury is rarely achieved in the brain and never in the spinal cord (SC) environment. This makes widespread SC injuries (SCIs) especially challenging to treat. Even though SC eNSCs give rise to astrocytes, oligodendrocytes, and neurons in vitro, they almost exclusively generate glial scar-forming astrocytes, seldom myelinating oligodendrocytes, and never neurons in mammalian models. We still do not know the exact SC niche cues preventing eNSCs from efficiently assuming oligodendrocyte and neuronal fates, averting a functional SC healing. Notably, SCI induces a vast immune response and I hypothesise that immune cells that are responsive to the SCI, contribute to eNSC niche formation, where they can exert an effect on eNSC regulation. I will investigate this by unravelling (O1) temporal, heterogenous immune responses to the SCI and (O2) their spatial interplay with the eNSCs using advanced methodologies, such as spectral flow cytometry and spatial transcriptomics. This will enable me to identify which of these immune cells affect eNSC gene regulatory networks leading to instigation of astrocyte but not oligodendrocyte or neuronal fates. Finally, (O3) I will identify SCI-specific enhancer elements of the immune cells of interest by comparing chromatin signatures of these immune cell types located across different tissues. This knowledge will present a ‘divide and conquer’ opportunity – to compartmentalise and disconnect immune system across different tissues enabling a targeted immune cell manipulation specifically within the SCI environment. The long-term outcome of this project will help the design of enhancer-based immuno-modulato