RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'A novel cost-efficient process to produce best-in-class prebiotics from side-products of the bioethanol industry' (BioAXOS) targeting Horizon 2020.

assistant: **Abstract**

Prebiotics (just like other fibres) are carbohydrates—humans do not digest them, but probiotic bacteria in our gastrointestinal tracts flourish on them, making it more difficult for dangerous pathogenic bacteria to multiply. Prebiotics occur naturally in many fruits & vegetables—in chicory roots, avocados, peas, dandelion greens, as well as in whole & sprouted grains. There is a growing body of clinical studies & other scientifical evidence attesting to their positive effect on our health.At the moment the most widely used prebiotic is inulin (40%+ market share). More efficient recent prebiotics, XOS and more recently AXOS have attracted a lot of attention , since they substantially improves on other characteristics of other types of prebiotics.We have developed BioAXOS—a novel effective prebiotic from XOS family that fulfils the described criteria can replace inulin in at least half of its applications, taking a market share of at least 20%. In the EU only this represents a total addressable market of €200m. This process can be run on any bioethanol production plant (or grain milling facility) enabling additional revenue streams for them. As a result of our Phase 1 feasibility study we have secured a strategic partnership with Pannonia Ethanol to produce BioAXOS, which will accelerate our time to market by 2 years.With BioAXOS we are targeting at least 10% of the total prebiotics market by 2027, and at least 40% in the longer term.In this Phase 2 project we are requesting a €1.9m contribution to industrialize the BioAXOS process, undergo necessary regulatory approval to be able to sell into human food applications, as well as carry out 3 trials with functional food producers.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'The first IVDR-approved commercial software solutions for AI-powered RNA-based companion and precision cancer diagnostics of acute myeloid leukaemia and bladder cancer' (QIandQD).

assistant: **Innovation**

Qlucore is developing visualisation-based analytical solutions with an established position in the next-generation sequencing (NGS) market. As pioneers in RNA-data analysis, we aim to revolutionise the field of companion and clinical diagnostics by developing software platforms integrating AI-powered machine-learning classification models for gene expression signatures and gene fusion analysis.By providing highly accurate and specific diagnoses, our platform represents the future of precision oncology, putting Europe at the forefront of AI-powered cancer classification. A software-based setup speeds up the introduction of new clinical guidelines and companion diagnostic solutions with the ultimate purpose of increasing survival rates and overall health. We aim to cover all cancer types relevant for gene expression-based diagnostics, and then scale up into non-cancer indications (e.g. cardiovascular and neurological diseases, immunological disorders) and other data types (e.g. proteomics and single-cell RNA-seq), further disrupting the precision diagnostics industry. Currently, we are preparing the solution with a classification model for B-cell progenitor acute lymphoblastic leukaemia (BCP-ALL) for the first IVDR certification (proof of concept). Building on those achievements and leveraging regulatory and data management experience, and progress, in the proposed project we will focus on acute myeloid leukaemia (AML) and bladder cancer (BC). For AML and BC we will develop and CE-certify classification models and companion diagnostics (CDx)-specific classification models. The successful completion of this project will significantly improve Europe's position in genomics- and AI-based precision diagnostics and as such prompt similar initiatives across Europe. This will all
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Vision, Insights and Trends for Awareness and Leadership in Media' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

Recent research activities in the ICT area, in particular in digital content and media sectors, has resulted in a number of technological enablers which allow the creation of new products and services. This has established a new converged social media environment in Europe as a playground for a large number of stakeholders, to ultimately enable creation of the related business, new jobs, and revenues benefiting from these developments. However, the main drivers of the new media and content technologies are the big industries, whereas the main users of these technologies are small enterprises / SMEs, which are creating product and services to reach the end customers – European and world-wide citizens. We can still observe a gap in discussions between the large technology providers and the small technology adopters, preventing the establishment of common strategies for the technology take up towards a more efficient creation of the new innovative product and services. Therefore, there is a clear need for the establishment of a common European community in the area of convergence and social media, in order to lay-down common research and innovation strategies, by involving important players from academia and research institutions, policy makers, end users, etc.Accordingly, one of the main goals of the VITAL MEDIA project is to enlarge the community in the social media area at the European level, at level of the national and regional clusters, through collaboration amongst the NEM Initiative and the clusters.  The enlarged community will be animated through a number of discussions at workshops to be organised at all mentioned levels and through cooperation within an innovative online collaboration tool, aiming to widely discuss and establish research and innovations roadmap
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Chronology of our Galaxy from Gaia Color-Magnitude Diagram fitting' in the context of a Horizon Europe call.

assistant: **Objectives**

The overarching goal of ChronoGal is to unveil the sequence of events and physical processes that have shaped the Milky Way (MW) from its early assembly to the present, by providing the holy grail of Galactic Archaeology (GA): precise age information. Our Galaxy is key to study disk galaxy formation and evolution, as it can be analyzed in exceptional detail using individual stars carrying the fossil record of its entire evolution. The importance of GA is underscored by the vast resources invested in it: Gaia parallaxes, homogeneous photometry, proper motions and velocities have transformed the field, aided by a huge effort from ambitious ground-based spectroscopic surveys.Despite spectacular recent progress, GA is nearing an impasse due to the lack of precise ages for large, unbiased stellar samples, which are critical for determining our Galaxy’s chronology. My unique expertise allows me to tackle this key issue by including color-magnitude diagram fitting in the field’s toolbox. Previously limited to studying external Local Group galaxies, this technique can finally now be applied to our Galaxy, providing unprecedentedly precise and homogeneous age-metallicity distributions for hundredths of millions of stars across all MW components. This is made possible by the accurate Gaia-based distances.ChonoGal’s ages will provide clear answers to persistent questions on MW evolution. Crucially, ChronoGal will precisely date the disk emergence, determine the duration of the enigmatic thick disk phase, resolve the debate on the presence of intermediate-age stars in the bulge, reconstruct the major halo building blocks and pinpoint the accretion time of these fossils of high-redshift dwarf galaxies. This will clarify the impact of mergers on shaping the stellar content and morpho
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'RESilience management guidelines and Operationalization appLied to Urban Transport Environment' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Increasing Europe’s resilience to crises and disasters is a topic of highest political concern in the EU and its Member States and Associated Countries. Regarding the specific case of transport systems, it can be said that those have developed a prominent safety and business critical nature, in view of which current management practices have shown evidence of important limitations in terms of resilience management. Furthermore, enhancing resilience in transport systems is considered imperative for two main reasons: such systems provide critical support to every socio-economic activity and are currently themselves one of the most important economic sectors and secondly, the paths that convey people, goods and information, are the same through which risks are propagated. RESOLUTE is answering those needs, by proposing to conduct a systematic review and assessment of the state of the art of the resilience assessment and management concepts, as a basis for the deployment of an European Resilience Management Guide (ERMG), taking into account that resilience is not about the performance of individual system elements but rather the emerging behaviour associated to intra and inter system interactions. The final goal of RESOLUTE is to adapt and adopt the identified concepts and methods from the defined guidelines for their operationalization and evaluation when addressing Critical Infrastructure (CI) of the Urban Transport System (UTS), through the implementation of the RESOLUTE Collaborative Resilience Assessment and Management Support System (CRAMSS), that adopts a highly synergic approach towards the definition of a resilience model for the next-generation of collaborative emergency services and decision making process.


**Keywords:** Urban Transport System, European Resilie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'A phase I/IIa clinical trial in Duchenne muscular dystrophy using systemically delivered morpholino antisense oligomer to skip exon 53' (SKIP-NMD), addressing dissemination and exploitation.

assistant: **Impact**

Duchenne muscular dystrophy (DMD) is a progressive, lethal muscle degenerative condition arising from the absence of dystrophin in skeletal and cardiac muscles. 65% of DMD boys have out-of-frame deletions. Modulation of pre-mRNA splicing by exon skipping is the most promising molecular intervention in DMD. 2 Phase Ib and 2 Phase IIa clinical trials (MDEX Consortium in collaboration with Sarepta Therapeutics; a Dutch Consortium) demonstrated that delivery of antisense oligonucleotides (AOs) to mediate exon skipping of exon 51 were able to return specific DMD mutations in-frame (~13% of all mutations) leading to new dystrophin protein expression after intramuscular and systemic delivery. The Dutch study of repeated 2-O-methylated phosphorothioate (2OMe) AO administration suggested limited efficacy after 5 weeks of treatment. Our MDEX Consortium study using a morpholino (PMO) AO demonstrated a clear dose response, robust dystrophin restoration and reduction of muscle inflammation after 12 weeks at doses up to 20mg/Kg, with no drug related adverse events. This, and preclinical studies focused on level of protein expression, clearly indicate that PMO have a superior therapeutic index compared to 2OMe. New PMOs are needed to target other DMD mutations. We will develop a PMO to skip exon 53 and perform a clinical trial in DMD boys using a world leading pan-European consortium. This will allow us to advance this class of PMO therapy in DMD by i. assessing the safety and efficacy of targeting another exon; ii. exploring the use of non-invasive techniques to monitor dystrophin restoration. This new PMO will be administered over 12 weeks in 3 groups, each of 4 DMD boys, receiving between 4 to 30mg/kg or placebo. If well tolerated, all boys will be treated for another 24 weeks at a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Management of avian influenza in a vaccination context' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

While outbreaks of highly pathogenic avian influenza viruses (HPAIV) in Europe used to be rare and geographically contained, the situation has dramatically changed in the last few years with thousands of outbreaks reported in domestic poultry and wild birds. Despite being an intensive field of research, many unknowns remain as we are still struggling to predict HPAIV emergence, avoid viral spread and limit the socio-economic impact entailed predominantly by control measures. Vaccination of domestic poultry against avian influenza, is now being given full consideration, as it is becoming clear that traditional prevention and control approaches alone will not curb the accelerating pace of occurrence of devastating HPAIV epidemics. On 1 October 2023, France became the first EU country to implement a nation-wide vaccination campaign in ducks. However, vaccinating domestic poultry does not come without important challenges. VIVACE therefore aims at putting together a doctoral network to contribute to fully integrate poultry vaccination approaches into efficient management strategies for HPAIV. We will do so by unravelling the impact current and upcoming EU vaccination policies will have on avian influenza virus evolution, surveillance and control strategies and societal burden of HPAI. This will be done through a combination of disciplines from life sciences, epidemiology, computer sciences and social and behavioural sciences. The training program proposed here includes scientific and transferrable skill sessions, builds on the integrated added values of complementing expertise (virology, immunology, modelling, spatial and molecular epidemiology, social psychology, economics and policy), and full access to state-of-the-art technologies in excellent environments. The consorti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Innovative mesoporous materials: industrial manufacture of highly ordered oxides as adsorbents and catalysts for sustainable and efficient processes (INORGPORE)' (INORGPORE) under Fifth Framework.

assistant: **Objectives**

The companies involved with this project have identified multisectorial applications for products based on new, highly ordered mesoporous materials. The potential processes associated with these materials are concerned with adsorption of molecules, which are too large to be absorbed by micro porous materials; chromatographic separation of chiral molecules or of natural products such as taxol; strong absorbers or catalysts for the decomposition of toxic molecules e.g. HCN, CNC1, arsenic- phosphorus or sulphur-containing substances; catalysts for deNOX; materials for the storage of fuel gases such as hydrogen. There is currently no European production of these inorganic materials based on alumina, silica, titania or zirconia so the project seeks to solve generic problems and with scale-up of laboratory methods for sustainable processes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Logistics Emission Accounting and Reduction Network'.

assistant: **Innovation**

Addressing emissions from transport is becoming increasingly important due to its increasing contribution to total greenhouse gas emissions and the link to high levels of toxic pollutants in places with a high concentration of transport activity. The contribution of freight transport to these issues is already significant, and will become more so due to continued globalisation of supply chains and further global economic growth.Efforts to address these issues are already underway. Transport companies have for a long time focused on their own activities because it is good business sense.More recently, collaborative green freight programs have been developed.  Several well-established industry-led green freight programs (Green Freight Europe, Lean & Green, ECO Stars etc.) developed to meet differing needs – operational data sharing to support benchmarking & reporting, efficiency improvement, reduction of toxic emissions in urban areas etc.Public authorities are also taking a greater interest because of targets to reduce transport CO2 emissions and improve air quality.  They are investigating a wide range of mechanisms, from incentives to access restrictions, and from vehicle-level certification of emissions to legislation requiring reporting.There is much activity ongoing in this area; however, much of it takes place in isolation. This creates problems – for example, confusion over the role of different programs, disagreement over the most effective mechanisms that can be used to calculate and report emissions, where support is most needed to encourage certain behaviours, or ignorance of practical measures under development.The overall goal of LEARN is to establish co-ordinated networks of industry, government and civil society stakeholders and build on existing initiativ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Christians among Muslims: Monasticism in early Islamic al-Andalus (8th-11th Centuries)' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

In recent decades, the archaeological and written records have been mobilised to update our knowledge of early Islamic al-Andalus and the subsequent transformation that the arrival of Islam brought about in the Iberian Peninsula from 711 onwards. This historiographical renewal has hardly affected however the study of Christian monasticism in al-Andalus after this defining moment during the early Islamic period (8th-11th c.). This project aims at providing a step-change in the way in which this phenomenon has been investigated until now by developing an innovative and unprecedented interdisciplinary approach to it through the integration of state-of the-art historical, archaeological and geological methodologies. The project will follow three levels of analysis (monastic architectures, ensembles and landscapes) applied to diverse selected territories and sites in what is currently Spain (Toledo, Cordoba, Merida, Granada) and Portugal (Mertola). The purposes are therefore to develop a technological and production understanding of monastic architectures as manufactured products in its social and economic contexts, to provide fresh insights into the spatial organisation and long sequences of monasteries, and to evidence their economic, social and politic roles and strategies in relation to others settlements shaping and reshaping the landscapes. It is intended hence to develop a suitable and updated methodology for the analysis of large multi-period monastic sites and landscapes, by offering a synchronic and diachronic perspective. The overall aim is to generate a broader vision that allows us to move from isolated churches and monastic ensembles to monasticism in al-Andalus, to feature its role in the relations between the Christian population and the Muslim authorities du