RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Exotic quantum states by locally-broken inversion symmetry in extreme conditions.' to be submitted under Horizon Europe.

assistant: **Abstract**

Strong correlations between electrons in solids lead to a variety of exotic quantum states like Mott insulator, unconventional high-Tc or odd-parity superconductivity. The groundbreaking discoveries of these states have not only generated huge advances in our understanding of condensed matter but also uncover a great potential for applications such as room-temperature superconductivity or quantum computing.Symmetry is an important concept in classifying quantum states. So far, the majority of research has focused on global symmetry. I have recently discovered striking experimental evidence that local inversion symmetry breaking opens up a new route for the appearance of novel quantum states of matter. Namely, it can induce novel types of odd-parity superconductivity with possibly topological character, a much-needed state for topological quantum computing. However, the effect of local inversion symmetry breaking on quantum states still lacks our control and understanding. In the Ixtreme project, I propose to generalise and exploit this concept by investigating materials with locally broken inversion symmetry as a platform of exotic quantum states. By measuring electric and thermal transport as well as magnetic properties in extreme conditions of very low temperature, high magnetic field and high hydrostatic and uniaxial pressure, the Ixtreme team will study and control the delicate interplay of local inversion-symmetry breaking with correlated electrons, magnetic and orbital degrees of freedom, topology, and superconductivity. Thereby, this project will establish new understanding of the physical properties of this promising novel class of unconventional metals and lead to new design methodologies for emergent states such as odd-parity superconductivity in locally non-c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Chromosome number variations in vivo: probing mechanisms of genesis and elimination' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

How variations in whole chromosome number impact organism homeostasis remains an open question. Variations to the normal euploid genome content are frequently found in healthy animals and are thought to contribute with phenotypic variability in adverse situations. Yet they are also at the basis of several human diseases, including neuro-developmental disorders and cancer. Our preliminary data shows that physiological aneuploidy can be identified in certain cells during development. Moreover, we have observed that when induced through mutations, non-euploid cells are effectively eliminated from the cycling population. A quantitative view of the frequency of non-euploid karyotypes and the mechanisms underlying their genesis is lacking in the literature. Further, the tissue specific responses at play to eliminate non-euploid cells, when induced through mutations are not understood. The objectives of this proposal are to quantitatively assess the occurrence of physiological chromosome number variations gaining insight into mechanisms involved in generating it. Additionally, we will identify the tissue-specific pathways involved in maintaining organism homeostasis through the elimination of non-euploid cells. We will use a novel genetic approach to monitor individual chromosome loss at the level of the entire organism, combine it with quantitative methods and state-of-the art-microscopy, and focus on two model organisms - Drosophila and mouse - during development and adulthood. We predict that the findings resulting from this proposal will significantly impact the fields of cell, developmental and animal physiology, generating novel concepts that will bridge the existing gaps in the field, and expand our understanding of the links between karyotype variations, animal develop
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Building an interactive AgriDemo-Hub community: enhancing farmer to farmer learning' in the context of a Horizon 2020 call.

assistant: **Objectives**

The overall aim of AgriDemo-F2F is to enhance peer-to-peer learning within the commercial farming community. The project will utilize the experience of different actors and involve practitioner partners throughout the project to deepen understanding of effective on farm demonstration activities (multi-actor approach). In a first step, we will conduct a geo-referenced inventory of open commercial farms that engage in demonstration activities in Europe, detailing the sectors, themes and topics on which they provide expertise, and describe the mediation techniques they apply. Case studies will be selected to perform an in-depth comparative analysis. Important dimensions in selection are: 1) a wide-spread geo-graphical coverage within Europe, 2) representative for EU-agricultural sectors, systems and territories and 3) low tech versus high tech in mediation techniques. Case studies will be described, analysed and compared on 1) their network structure (actors, roles and governance characteristics), and 2) the mechanisms and tools used for recruitment, interaction and learning. Furthermore, effectiveness of the different approaches within the case-studies will be assessed through an evaluation of the extent and nature of learning. Both regional and international multi-actor meetings will use the results of the cross comparative case study analysis to i) identify a set of best practical approaches for both the on farm demonstration of research results (science driven) and the spreading of best farming practices among practitioners (innovation driven) and ii) recommendations for AKIS governance and policies on how to support effective on farm demonstration activities. The empowerment of both the commercial farming and policy community to uptake these best practices will occur
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Towards a clinical implementation of phase contrast radiology' to be submitted under Sixth Framework.

assistant: **Abstract**

Low absorption differences, leading to poor image contrast, are one of the main limitations in diagnostic radiology. This is particularly relevant in the field of mammography, where the detection of small nodules, which would result in an early detection of the disease with consequent reduction of the mortality rate, is severely affected by this limitation.It has been demonstrated that phase contrast imaging, an innovative technique based on phase effects, has the potential of removing to a large extent this limitation, and thus of pushing forward the state-of-the-art of diagnostic radiology. The aim of the present project is the clinical implementation of phase contrast imaging.The technique has been developed mainly in synchrotron radiation environments, which has prevented its widespread application despite the extremely high potentials: the application of the technique is in fact limited by the necessity of a high coherence in the x-ray source, as well as by the requirement of a high detector spatial re solution.Provided that source-to-sample and source-to-detector distances are optimised, modern, high power micro-focal x-ray sources are capable of providing enough coherence: several studies have demonstrated that, while a high spatial coherence is strictly necessary, the requirements on temporal (chromatic) coherence are much more relaxed.In addition, I recently developed, in the framework of a synchrotron radiation experiment, a technique capable of removing the limitations on the detector spatial resolution, based on the design of specific slit systems. By precisely characterizing a micro-focal source and a flat panel detector, the above technique would enable the design of set-up suited to the specific source-detector combination.This would allow the realization
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Analogical Reasoning and Conceptual Change in Physics Education' (2007-2013).

assistant: **Innovation**

Educational researchers have shown that a key difficulty in teaching science, and in particular in teaching physics, is how to bring about conceptual change (Posner, Strike, Hewson, & Gertzog,1982). The instruction of complex concepts in science, and especially in physics, often involves some use analogies. This research proposal aims to achieve two main goals: (1) Develop an empirically based theory that explains how and to what extent instructional analogies affect conceptual change during the acquisition of new knowledge in physics; (2) Derive practical recommendations from this theory regarding the use of analogical reasoning when teaching science, and particularly when teaching physics in high school and at the introductory undergraduate level, to achieve conceptual change. This will be done by conducting clinical interviews (Clement, 2000) which will lead to the design of a set of learning activities in a design experiment mode (Cobb, Confrey, diSessa, Lehrer, & Schauble, 2003) that will be used for iterative clinical teaching studies of key topics in physics that traditionally involve analogical reasoning. The innovative features of this research are as follows: (1) The learning events that are prompted by analogical explanations will be studied using two research methodologies employed to measure conceptual change, namely knowledge analysis (diSessa, 1993, 2004), and microgenetic analysis (Siegler & Crowley, 1991). (2) The theoretical framework guiding this analysis will be the 'Knowledge in Pieces' theory of conceptual change (diSessa, 1988, 1993). The proposed research will contribute to European excellence and European competitiveness in the following ways: (1) It will strengthen the cognitive components of educational research in science education, (2) It wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Cost-efficient origin/destination estimator', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The project intends to develop a cost-efficient method for developing region-to-region transport matrices of flows based upon the economic values of the regions involved. The premise is that the economic information is often accessible, whilst transport flows measurements are missing; on the other hand, a strong correlation is expected between transport and economy: if such a model function could be established and applied to countries lacking detailed information, then a cost-efficient instrument would be made available to construct origin x destination matrices, which is an essential component of one of the data categories defined in the information systems: general databases.The estimation of domestic and international origin x destination matrices for freight and passenger flows will be attempted with respect to different characteristics of these flows, such as commodity and transport mode in case of goods transport, and motive and transport mode for passenger flows.This study concentrates on modelling inter-regional freight and passenger flows in those cases where full information is not available but highly desired. %A secondary objective is its application to the Eastern European countries. The current lack of transport registrations in a rapidly changing transport situation makes the need for transport flows statistics even more crucial. The model developed in this project will be used to estimate the newly coming transport flows, based upon economic factors by region. Application to the example of Hungary where efforts have recently be spent to build up a regional economic database could serve as a test case. In countries like the Central and Eastern European countries, the shortage of information will continue to exist as long as no adequate transport informat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Exploring Natural Immunity in Retinal Neovascular Disease' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in the world. The number of people with AMD has reached 196 million, with ~1 in 10 people over 55 years already showing early signs of the condition. 70% of those who progress to late-stage disease will develop neovascular (nv)AMD due to uncontrolled growth of blood vessels behind the retina. In fact, aberrant growth of retinal or choroidal vasculature is a hallmark of diabetic retinopathy and nvAMD. Collectively, these are the most common causes of central vision loss globally.  Identification of new biological processes that regulate neovascularization are urgently needed to open new therapeutic options for patients. This is a challenge; but with recent longitudinal studies showing unequivocally that current gold-standard care has a therapeutic ceiling, it presents a critical unmet clinical need.  I have recently discovered that natural killer cells (NKs) are found in neovascular lesions in human AMD and our mouse model data suggests that these innate lymphoid cells (ILCs) play a role in inhibiting pathology. Using scRNAsequencing I discovered a defined subset of NKs in neovascular lesions in a model of resolving nvAMD. I now hypothesize that, in contrast to expectations, these ILCs play a critical role in remodelling neovascular lesions, limiting pathology as opposed to exacerbating it.  NK cells are completely unstudied in the retina. Here, I propose that manipulating NK cells may represent a novel therapeutic strategy for the prevention and treatment of neovascular eye disease.  Objectives:   1) Examine NK cell function in models of retinal neovascular disease 2) Profile NK cells in AMD pathology in a human study 3) Develop microfluidic “neovascular retina-on-a-chip” model to exam
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Artificial Intelligence in Secure PRIvacy-preserving computing coNTinuum'.

assistant: **Concept**

Artificial Intelligence (AI), to become fully pervasive, needs resources at the edge of the network. The cloud can provide the processing power needed for big data, but edge computing is close to where data are produced and therefore crucial to their timely, flexible, and secure management.  AI-SPRINT will define a framework for developing AI applications in computing continua, enabling a finely-tuned tradeoff between performance (e.g. in terms of end-to-end latency and throughput) and AI model accuracy, while providing security and privacy guarantees. AI-SPRINT outcomes are: i) simplified programming models to reduce the steep learning curves in the development of AI software in computing continua; ii) highly specialized building blocks for distributed training, privacy preservation and advanced machine learning models, to shorten time-to-market for AI applications; iii) automated deployment and dynamic reconfiguration to decrease the cost of operating AI software. Beneficiaries include end-users of AI systems, software developers, system integrators, and cloud providers.  AI-SPRINT tools will make it possible to consider security and privacy early in the design stage and to seamlessly manage the time-varying conditions typical of real environments. Real-world scenarios are an integral part of AI-SPRINT as key to guiding requirements and development and validating results. Three heterogeneous use cases (farming 4.0, maintenance & inspection, and personalized healthcare) are built by industrial partners. Cutting-edge innovation is brought to the Consortium by four research partners with complementary expertise. Two system integrators provide vision on relevant verticals and technology insights, one cloud provider brings real-world implementation expertise, and two speci
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Analysing the impact of pedagogical models within and between collaboration contexts through students' collaboration experiences' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Collaboration in technology supported environments has become increasingly important for professional contexts. Many companies require that future employees are proficient in such collaboration. Computer-Supported Collaborative Learning (CSCL) is well-suited to teach students the dynamics and skills needed for collaboration in technology supported environments. A large collection of pedagogical models have been shown to stimulate collaboration in electronic environments. A pedagogical model offers a collaboration practice believed to be more effective. Yet, collaboration breakdowns are still observed. Such a breakdown could be caused by a conflict between the pedagogical model and students¿ collaboration experiences or beliefs about collaboration. For exam ple, it is well-known that students¿ experiences with various teaching and learning environments are reflected in their study approach. It is likely that the perception of the context determines their engagement. Hence, it is conceivable that students in a collaboration context do not work according to the model(s) that they are offered, but prefer an idiosyncratic model or a model that they are familiar with. Pedagogical models also have a specific focus on cognitive (learning), motivational (involvement) , or social processes (interaction). CSCL studies focus on the effects of the pedagogical model on the process that it targets (direct effects). Studies that focus on reciprocal relationships between these processes - within and between contexts - are rare. This project will increase our understanding about effective collaborative learning by 1) investigating students¿ collaboration experiences to illustrate the impact of students' past experiences on current behaviour and development of beliefs, 2) tracing students
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Environmental Management Architecture for Information Delivery' (E-MAIL).

assistant: **Concept**

The main aim of E-MAIL is to develop telematics applications to support decision-makers in regional public organisations in the environment sector. The applications will support these users in environmental monitoring and planning by combining and using data captured from different sources. This information will be converted to standardised formats and integrated on a multimedia platform containing an integrated set of tools for modelling, mapping, analysis and reporting.The objective is to provide the E-MAIL user with efficient support systems for obtaining in-depth information on key environmental topics and environmental indicators. These include census data on population and dwelling, urbanisation and sustainable development planning, actual and potential ecological risks, surface and ground water quality, water resources management, defence from flash-floods, habitat management and conservation, waste management, pollution and industrial risks.The project is based upon work in four different European Regions: Tuscany, Rhone-Alpes, Fife, and Corfu. Each region exemplifies a different set of characteristics: a river basin, an agricultural area, an industrial area, and an island. The Public Authorities involved in the environmental management of these areas will be provided with a common set of tools for data analysis, synthesis, interpretation and simulation. The tools will be designed to enable them to undertake more accurate monitoring of the environmental indicators relevant to their region, and thereby ensure more effective and better targeted environmental planning and policy actions. Major Validation SitesAutorità Bacino Arno, ITRegione Toscana, ITFife Regional Council, UKChamber of Commerce and Industry, Lyons, FRCorfu Initiative, GR UsersThe users are environ