RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Hypertension Susceptibility in African Migrants: Solving the puzzle through transcontinental prospective cohort study design' (Pros-RODAM) under Horizon 2020.

assistant: **Objectives**

Hypertension is the most important modifiable cardiovascular risk factor. Migrants, especially people of Sub-Saharan African heritage, are extremely affected for reasons that are unclear. This project aims to understand the mechanisms underlying the high risk of hypertension among African migrants by assessing the role of epigenetic modifications that result from rapid socio-environmental and behaviour change. To achieve this, Agyemang and his team will establish an innovative transcontinental prospective cohort study of a homogeneous group of Sub-Saharan African migrants (Ghanaians) living in the Netherlands and non-migrant Ghanaians living in rural and urban Ghana. We will first examine and identify the key changes in modifiable environmental factors influencing the high risk of hypertension among migrants. Second, we will examine changes in epigenetic modifications and their effects on hypertension risk in migrants. Third, we will identify the key environmental factors that are driving the epigenetic changes. Last, we will estimate for the first time the individual and combined effect of environmental factors, and epigenetic modifications to the high risk of hypertension in migrants relative to non-migrant Europeans and Ghanaian counterparts living in Africa. This project will yield new insights into the key drivers of hypertension and deliver a major breakthrough in knowledge about prevention and treatment among African and other population groups.


**Keywords:** Migration and health,  Sub-Sahara Africa,  hypertension,  lifestyle,  psychosocial factors,  social determinants of health,  epigenteics,  intercontinental prospective cohort
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Bridging the gap between Mind, Brain and Body: exosome role and monitoring'.

assistant: **Objectives**

MindGAP presents a radical new vision that may BRIDGE the GAP between HEALTH status and MIND/BODY interactions and lead to a paradigm shift in medicine. The disruptive idea presented herein is sustained by relevant data presented in the literature: (i) exosomes circulate throughout the body as messengers of health and disease, transporting genetic data to be delivered into a recipient cell; (ii) and exosomes are implicated in brain activity, having the ability to cross the blood brain barrier.   Thus, when exosomes circulate and exit the brain to peripheral cells, there is a message transported therein, which is related to its cargo inside the vesicle. Overall, we aim to know which cargo is related to health and which cargo is related to disease. Traditionally, everyone has been looking for disease indicators to detect disease. Herein, we look for sensitive health indicators that may change under disease installation, therefore yielding an unprecedented early disease detection possibility.   Moreover, the possibility of using MINDFULNESS meditation as a mind-related tool to control the cargo of exosomes is explored herein. If meditation is successful in changing the behaviour and attitudes of many people, fighting depression, etc., it means that the exosomes cargo may be changed through this process. Thus, this could be a major route to a self-healing approach before disease begins.   Finally, all this knowledge opens doors to an innovative device that may be used by everyone to understand his/her health status.  Overall, MindGAP targets (i) the missing relation between the genetic data in EXOSOMES and health status; (ii) interfacing this link with MIND-related activities; (iii) and to create an INNOVATIVE and PORTABLE DEVICE that TRACKS EXOSOMES and ANALYSIS their rele
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'A Biocentric Ethic of Sustainable Agriculture'.

assistant: **Concept**

BIOTA will develop a biocentric ethic of sustainable agriculture to address the lack of biocentric theorising in agricultural ethics and thereby promises to create a new sub-field in environmental philosophy. This necessary theoretical innovation will provide appropriate normative guidance for agricultural practices by reflecting on the plurality of different nonhuman lifeforms that are either the objects – like plants – or enablers – like soil microbes – of agricultural activities. Therefore, BIOTA pays particular attention to the often-overlooked non-sentient organisms facilitating agricultural practices, with a specific focus on plant agriculture (grain, vegetable and fruit farming) – which is frequently attributed a key role in sustainability transitions. Three interlinked layers (representing three objectives) form the core of BIOTA and – ideally – of any adequate biocentric agricultural ethic: (1) Biocentric theories argue that all living beings (incl. non-sentient organisms) are morally considerable. BIOTA will improve existing biocentric accounts by rethinking their main premisses in a more nuanced and relational way.(2) By developing agricultural ethics from a biocentric perspective, BIOTA will not only consider the farmer as a moral agent but put myriads of life forms that make agricultural practices possible into the centre of moral theorising (plants, the soil biota incl. bacteria, fungi and insects).(3) By theorising biocentrism in an empirically informed manner, BIOTA will develop its agricultural ethic in a way that reflects on environmental and technological change. That entails introducing systemic aspects beyond the typical scope of biocentrism – by reflecting on sustainability and socio-ecological resilience –, theorising on novel biotechnologies, and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Well-being improvement through the Integration of healthcare and reSearch Data and models with Out border for chronic iMmune-mediated diseases'.

assistant: **Objectives**

Enabling integration of medical and research data, secure data sharing and leveraging responsible state-of-the-art artificial intelligence (AI)-mediated models opens immense possibilities to mitigate the impact of chronic immune-mediated diseases (CIMDs) affecting 10% of Europeans. Eight European universities, leaders in the medical and analytical field, three SMEs, one research institute and one company, at the forefront of clinical AI implementation, data infrastructure, and security, and a Patient Organisation formed the consortium WISDOM. The consortium's overarching aim is to convert complex biological information from the existing data sources into actionable insights. WISDOM builds on the premise that computational tools can provide valuable knowledge and guide decision-making at critical stages in the individual patient journey, from diagnosis to treatment initiation and optimisation. To unlock the potential of the existing data, WISDOM will address barriers of data integration and accessibility and deploy novel approaches for data processing, harmonisation, integration, and secure, trustworthy data sharing with federated access. WISDOM aims to develop computational risk stratification and outcome prediction models and tools in different CIMD use cases, building on large EU-funded multimodal datasets, and prospectively validate them on technical, clinical and user aspects to facilitate data-driven and patient-focused diagnosis, treatment, and monitoring. WISDOM aims to promote the widespread utilisation of data and facilitate responsible and critical assessment of the use of AI in healthcare using an end-user guided approach leveraging collaboration among clinicians, researchers, legal and AI experts, patient associations and rich stakeholder expertise. WISDOM’s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'ROtational Motions: a new observable for seismologY', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

When the ground shakes from earthquakes, the oceans, or the atmosphere, it not only translates (up-down, sideways), but also undergoes rotational motions. To fully characterize seismic sources and wave fields theoreticians have insisted for decades that these motions should also be measured. However, this was hampered by the substantial technical difficulties in observing rotational motions with the necessary sensitivity. This implies that the observation of the complete ground motion is still an unsolved problem. Based on promising pilot studies in the past years, we aim at breaking new ground with an innovative instrumentation strategy that would allow solving this outstanding problem. If the strategy is successful the new observable is expected to have an impact in a wide range of fields making it a classical high-risk high-gain situation. We aim at the establishment of the first-of-its-kind six-component seismic observatory based on ring-laser technology, the field deployment of portable fibre-optic based rotation sensors,  the integration of the  new observations with the global seismological data infrastructure, and the reporting of discoveries in a variety of fields based on the new observable. At the end of the project we expect to have substantially pushed forward the emerging field field of rotational seismology with new standards, and recommendations for the use of rotation sensors in Earth sciences and engineering. We expect advances in understanding 1) the dynamics of volcano’s interior, 2) the origin of the Earth’s ocean generated noise field, 3) and seismic inverse problems for structure and source using the new rotational observables. This will impact several pressing problems of societal relevance in particular in association with natural hazards such a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Establishing the scientific bases and technical procedures and standards to recover the European flat oyster production through strategies to tackle the main constraint, bonamiosis' (OYSTERECOVER).

assistant: **Innovation**

The European flat oyster, has been part of the human diet for many centuries. High mortality episodes and overfishing decimated the populations of O.edulis in Europe through the first half of the XXth century. Then, two diseases (due to Marteilia refringens and Bonamia ostreae) spread in the early 1970s and 1980s, drastically reducing the production. Despite new management practices, and intensive repletion programmes, the production of O. edulis has remained low since that time. The recovery of European flat oyster production is seen as an important opportunity for the shellfish industry in Europe. Thus this project proposal aims to attain a clear competitive advantage for a number of SME AGs and their members for different reasons: 1st- Chance to diversify production (risk management) 2nd- High market value of the product. 3rd- Environmental positive effects of fostering aquaculture activities based on native species 4rd-Biotechnology provides tools and procedures to face the oyster industry problems that were not available until recently A total of five Shellfish Producer Associations from four different Member States and three SMEs in major oyster production countries in Europe, concerned about the above mentioned issues and being aware of recent scientific progress in selective breeding programmes for bonamiosis tolerance, decided to work together with the common general objective of facing the challenge of establishing the scientific and technical bases, procedures and standards that allow the recovery of the O. edulis production, through development of strategies to tackle the main constraint, bonamiosis . To successfully achieve this goal those European Research Centres and Universities which have mainly contributed to scientific progress on O. edulis recovery a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The development and evaluation of natural and sustainable methods for the regulation of fertility in production systems for small ruminants' to be submitted under Sixth Framework.

assistant: **Abstract**

This proposal will establish a European training and research centre of excellence for sustainable reproduction. From this a new generation of scientists will emerge with the technical expertise and a culture of sustainability to address key issues of sustainable animal reproduction. Training for post-graduate and post-doctoral students in: cellular and molecular reproduction, applied reproduction and reproductive technology, experimental design, data analysis, interpretation and presentation and scientific English There will be 2 types of training (i) PhD and Post-doctoral A research-driven program based around the expertise of the applicant and INRA and comprising studentships and fellowships. The studentships and fellowships will be at INRA, They will be of 3-year duration and they will be linked to the research component of the proposal. Summer schools on specialist subjects will be held to complement research training. (ii) MSc - University of Tours A two year course on sustainable animal reproduction with lectures and a research project. Taught modules include: Cellular and molecular Reproduction, Animal production, Animal welfare and ethics, Research methods and scientific English. The taught modules last 18 months and will be assessed by written and oral examinations. The research module (6 months) at any approved institution researching in any taught component of the course and will be assessed by thesis. Research will be on developing natural methods for manipulating reproduction in small ruminants to produce healthy hormone free food that meets the criteria of sustainable animal production. The emphasis will be on understanding how the animal's environment affects its reproduction and then applying this knowledge to develop natural methods for sustainable ani
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Experimental study of particle transport and deposition in pyroclastic flows and comparison with ignimbrites in Tenerife'.

assistant: **Innovation**

Research objectives and content Our project is aimed to improve our understanding of transport and deposition of pyroclastic flows . Pyroclastic flows are hot suspensions of particles in gas produced during some volcanic eruptions. They travel at high speed and represent a major threat on most volcanoes of the world. The project includes a detailed experimental study of sedimentation in particle-laden gravity currents generated in a 16 m-long flume. It will focus on the influence of variables such as flow rate, grain size and density distribution, concentration and topography. Application of the experimental results to the natural case of pyroclastic flows will pass through a sedimentologic study of ignimbrites in Tenerife (Islas Canarias). Extrapolation from the experimental aqueous system to the natural gaseous system will also require an experimental study of particle settling velocities in gaseous suspensions, for which a new apparatus will be built. The final objective is to find out unambiguous field criteria to infer the pyroclastic flow dynamics from the deposits. Training content (objective, benefit and expected impact) This post-dostoral research should allow me to improve and extend my skills in analogue experimental volcanology as well as my understanding of the dynamics of pyroclastic flows, which is one of the most promising issue for volcanic hazard mitigation. Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Data Spaces: Making Sense of Health in an Age of Cross-Border Data Infrastructures' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

DataSpace proposes a new conceptualization of how the pursuit of health is shaped by data. Healthcare is increasingly datafied and a wide range of actors – patients, clinicians, administrators, policymakers and industry – want to be able to exchange and access health data across national boundaries. Competing initiatives for fostering cross-border data integration proliferate, and the EU provides major investments, e.g. through the European Health Data Space. These massive investments will influence healthcare, administration and research, but we do not know how. DataSpace explores what is driving the establishment of cross-border health-data infrastructures, which types of infrastructures are being established, with which implications for whom, and what comes to be included and acted upon in relation to health, organizational performance, and health policy. Furthermore, these investments emerge in tandem with wider social changes where data have become constitutive for the lives we can live. With DataSpace we therefore explore and conceptualize how people experience themselves and the world around them with and through data. We take the term ‘space’, empirically present in the EHDS initiative, and reinvigorate it theoretically to establish a vocabulary fitted for understanding data-intensive health environments. We suggest seeing data spaces as having both formative and experiential dimensions and explore how they interact. Concerning the formative dimensions, data spaces are enacted through promises, work, and users. Four experiential dimensions relate to what is experienced as right (legally and morally), true (epistemologically), present (phenomenologically) and valuable (economically, emotionally, and socially). This theoretical approach moves beyond problematic di
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Exploring a Future Internet suited to a probable paradigm shift in global societal developments' (PARADISO2), addressing dissemination and exploitation.

assistant: **Impact**

The project has the ambition to amend a paradoxical situation: to a large extent, the Internet of the future is explored today without investigating how our societies might or should evolve in the future...<br/>PARADISO2, building on the successful achievements of the PARADISO FIRE project selected at FP7 Call 1, aims at exploring a Future Internet suited to a probable paradigm shift in global societal developments, characterized by substantially revised economic, environmental and social objectives in order to avoid major risks of breakdown.<br/>This envisioned Future Internet will be fully analyzed and specified, and presented in the PARADISO reference document" that will also include precise recommendations for the preparation of FP8. The specification will allow being ready to validate the approach through the FIRE experimental facility<br/>The PARADISO2 partnership is the same one who successfully developed PARADISO activities and is constituted by two complementary and fully committed organisations: the Club of Rome and Sigma Orionis. Beyond this formal partnership quite a unique high-level international expert panel will be actively involved in the exploration of the envisioned Future Internet.<br/>The project aims at contributing putting Europe at the forefront of Future Internet developments, involving the greatest number of stakeholders (including the PARADISO worldwide community) and having the highest impact. To reach these objectives, two open project events will be organised (a PARADISO scientific workshop and the 2nd PARADISO conference), the PARADISO web site will be further enhanced with Web 2.0 and push technologies, and substantial dissemination activities will be undertaken.<br/>The sustainability of the momentum created by PARADISO beyond the formal