RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Innovative Multi-purpose off-shore platforms: planning, Design and operation'.

assistant: **Concept**

European oceans will be subject to massive development of marine infrastructure in the near future. The most obvious is the energy facilities e.g. offshore wind farms, exploitation of wave energy, expansion of electricity connections, and also further development and implementation of marine aquaculture. This will also lead to an increased need for marine infrastructure to support installation and the on-going operation of the facilities. However both economical costs and environmental impact have to be reduced in order to increase the feasibility of the use of ocean space.Marine structures for offshore wind farms and aquaculture have to be installed at various sites and on much larger scale than earlier implementation of offshore structures in order to fulfil EU strategies (1) for reduction of fossil-based energy and (2) to become a major player in sustainable aquaculture. However the feasibility is much more sensitive to the costs of structures and the installation of the structures than for instance Oil & Gas facilities.Novel innovative design concepts should address different physical conditions in order to make the best use of the ocean space.  Going from deep water (north of Spain) to shallow water with high morphological activity (the Wadden sea) and further to inner waters like the inner Danish/Baltic areas and the Adriatic sea changes the focus from a strong physical aspect to environmental impact. This will make it possible to develop, test and integrate different technologies but also to address site specific challenges.Both for offshore renewables and for aquaculture a substantial part of the costs is variable cost related to operations and maintenance of the plants. It is obvious that optimization of the use of ocean space for different purposes might benef
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Signaling circuitry controlling fungal virulence: identification and characterization of conserved and specific fungal virulence genes as common antifungal targets'.

assistant: **Objectives**

Fungi are heterotrophic microorganisms with devastating impact on agriculture and human health. Agricultural production worth billions of € is destroyed annually by fungal diseases. Human fungal infections have severe consequences on the growing number of immuno-compromised patients, with high mortality rates associated with Aspergillus and Candida infections. There is a critical need to further the development of new antifungals, which requires a comprehensive molecular knowledge on fungal pathogenesis and signal transduction. ARIADNE uses a comparative biological approach at the systems biology level to identify and validate signalling target genes that play an essential causative role in fungal virulence on both plant and human hosts. To establish a comprehensive view of fungal pathogenesis seven pathogenic species will be studied, including the two major fungal pathogens of humans Aspergillus fumigatus and Candida albicans, the devastating plant pathogens Fusarium oxysporum, Magnaporthe grisea and Mycospherella graminicola, as well as two established model pathogens of filamentous and dimorphic fungi, Ashbya gossypii and Ustilago maydis. This array of fungal species cuts across diverse taxonomic groups, covering several hundred million years of evolution. The central scientific and technological challenges for ARIADNE are to 1) integrate parallel transcriptomics, proteomics, and chemical genetics for a comprehensive set of major fungal pathogens, 2) identify evolutionarily conserved and species specific signalling effectors which act as key players in fungal virulence, 3) validate these proteins as candidate targets for small molecule inhibitors. This groundbreaking scientific and teaching approach will open up new avenues on how to look at fungal pathogenicity and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Characterization of myoepithelial differentiation in basal-like breast cancer cells' to be submitted under Seventh Framework.

assistant: **Abstract**

Translational research in cancer is one of the thematic priorities within FP7 Health Investigation Programme. Breast cancer is the most frequent tumour type in European women. 20-25% of breast carcinomas express myoepithelial markers, thus showing the basal-like phenotype. Basal-like tumours are typically high-grade, aggressive cancers with poor prognosis. Since basal-like phenotype closely resembles that of breast pluripotent stem cells, it has been suggested that these tumours may originate from the transformation of stem cells that have undergone a block in their differentiation program.   The aim of this project is to assess the capacity of basal cells to differentiate to fully functional myoepithelial cells in an attempt to uncover the molecular mechanisms regulating the cell fate decisions made by normal and cancer breast stem cells that drive them to full versus incomplete myoepithelial differentiation.  To this end, cell subpopulations with bi-lineage progenitor features will be isolated from basal-like (normal and tumourigenic) breast cell lines and their ability to conduct complete myoepithelial differentiation will be tested. The differentiation process will be further characterized by gene expression profiling in order to identify novel candidate genes involved in this process. The results obtained will be translated to the study of human breast cancer by two complementary approaches: (i) in silico analysis of gene expression data from basal-like tumours, (ii) immunohistochemical studies in normal and tumour breast samples. Finally, in vitro and in vivo functional studies will be performed to further define the role of candidate genes in myoepithelial differentiation.   As cancer stem cells are suggested to be resistant to chemotherapy and responsible for tu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Euroconference Rings, Modules and Representations - Constanta 2000' (1998-2002) under Fifth Framework.

assistant: **Objectives**

The last high-level international conference on algebra with a wide variety of topics took place in 1996 in Miskolc, Hungary. There have been other meetings since then, but they all dealt with very special, although certainly important aspects of algebra.One objective of our conference is to present to the audience the rapid recent developments in various fields of algebra, such as for example: - quantum groups and Hopf algebras, - quasi-hereditary algebras, - non-communicative algebraic geometry, - Hall algebras, - higher dimensional orders, - representation theory of groups, cohomology and infinite dimensional modules, - PI-algebras, - the Burnside problem. The conference will consist of survey lectures by the specialists in the morning and shorter lectures by other participants in the afternoon.By now we have commitments from the following specialists in the various fields of algebra listed above: Henning Andersen, University of Aarhus; Michael Artin, MIT; Michel van den Bergh, University of Limburg; Michel Broué, University of Paris VII; Jon Carlson, University of Georgia; Alexandr Kemer, Moscow State University; Susan Montgomery, University of Southern California; Claudio Procesi, University of Rome; Idun Reiten, University of Trondheim; Jeremy Rickard, University of Bristol; Claus Ringel, University of Bielefeld; Toby Stafford, University of Michigan; Efim Zelmanov, Yale University. The conference will be preceded by a 10-day workshop financed by NATO in which the participants will be introduced into the topics of the conference through series of lectures held by our main speakers.ftp://ftp.cordis.lu/pub/improving/docs/HPCF-1999-00081-1.pdf
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Mapping, understanding, assessing and predicting the effects of remote working arrangements in urban and rural areas' (R-Map).

assistant: **Innovation**

R-Map aims to analyze the impact of remote working arrangements (RWAs) on the disparities between urban and rural regions in Europe. The project bases its research on the premise that understanding and shaping the trends related to the emergence of RWAs provides an opportunity to bridge the urban-rural divide affecting its multiple facets. To achieve its goals, R-Map will produce an Integrated Impact Assessment Framework (powered by the R-Map model) that will allow the assessment of individual, social, economic, environmental and spatial impacts of RWAs. A visualization platform will be developed leveraging the R-Map model to provide visualization and interactive services allowing decision-makers to monitor and assess how remote work arrangements affect people, communities, space, economy, and environment in urban and rural regions. The developed tools will be applied at local level to monitor and assess current remote working trends across six representative use-cases in the EU and the AC, in regions within Greece, United Kingdom, Italy, Turkey, Netherlands-Germany, Austria-Switzerland (two cross-border cases). Using scenario building and forecasting methodologies, R-Map will move on to explore the potential future impact of remote work in these regions for the next 5-10 years and formulate policy recommendations on how to create environments conducive to remote work, that are tailored to the needs of local governments in both urban and rural settings. Cross-regional exchanges between stakeholders and policy roundtables will help move beyond the regional focus ensuring the replication of results across areas with different characteristics in Europe and beyond. By taking a comprehensive approach to research on RWAs, R-Map addresses the role and the needs of policymakers
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Characterization of glycoslation structures of pharmaceutical proteins produced in plants with dna-microarrays and glycoprotein fingerprinting' in the context of a Fifth Framework call.

assistant: **Objectives**

The effects of glycosylation of proteins are gaining more and more importance, e.g. requirements. Numerous production techniques of recombinant proteins as drugs are developed at the moment. The quality for the pharmaceutical effect of those drugs is often dependent on the glycosylation status. Therefore a constantglycosylation is most crucial and needs to be monitored. Healthcare Technologies has developed a system and reliable method of glycosylation fingerprinting. Phytowelt is working on the production of recombinant proteins in plants and normal profiling by coda micro arrays. To access the utility of this production system both companies aim to evaluate the compatibility of their diagnostic systems to develop a safe and cost efficient production method combined with a method to monitor product quality and reliability in a cost efficient way.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Mechanical stress model for packaged ICs'.

assistant: **Concept**

The primary objective of the MESMERIC project is to produce a standard silicon test chip, which can be used to:(a) Characterise current/future microelectronics/optoelectronics packages and(b) validate thermal/mechanical models of packages.This chip will be fabricated on a standard foundry process, and thus will be easily available at minimum cost. Users will be able to verify their FE models by comparing the modelled results with measured results obtained directly from the test chip. Thus, it meets the aims of Key Action IV.8,1 & IV.8.4 by allowing users to rapidly adopt thermo-mechanical modelling techniques due to the availability of a standard and proven European test chip. This project addresses specific areas of concern in the Community, relating to access, ease of use, cost-effectiveness and standardisation. It will provide a generic test capable of meeting all thermo-mechanical measurement needs across a wide range of package types. A feature of the project will be the innovative circuit features strain gauge characterisation methods and compact, user-friendly test hardware/software.Objectives:These are 8 key objectives of the MESMERIC project:- Provision of a standard, easily available and cost effective test chip to European users.- Provision of on-chip PROM and decoder circuitry to give automatic traceability of individual die.- Provide a PC-compatible desktop interface unit, to give a convenient, small footprint test capability that does not require scarce laboratory or production resources,- Provide strain gauges, heaters and temperature measurement capability.- Provide size flexibility to allow the test chip to be used in a wide range of package sizes,- Detailed mapping of the stresses on the silicon surface will be provided by arraying a large number of ga
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Physical Cognition for Intelligent Control and Safe Human-Robot Interaction' (Sestosenso) targeting Horizon Europe.

assistant: **Abstract**

Sestosenso develops technologies for the next generations of collaborative robots capable of self-adapting to different time-varying operational conditions and capable of safe and smooth adaptation from autonomous to interactive when human intervention is required either for collaboration or training/teaching. The project proposes a new sensing technology from the hardware and up to the cognitive perception and control levels, based on proximity and tactile sensors embedded in the robot body, providing a unified proxy-tactile perception of the environment, required to control the robot's actions and interactions, safely and autonomously.Sestosenso is motivated by the industrial need to integrate workers with robots and the need for robots that could operate safely without out-of-the-robot infrastructure, thus reducing robot setup times and costs and increasing the flexibility of the shopfloor configuration.The Sestosenso technology is demonstrated by three Use Cases of industrial interest: cooperative assembly (automotive), handling and packaging (logistics), and cooperative harvesting (agriculture).


**Keywords:** Robotic Cognitive Perception, Human-Robot Interaction, Robot Sensors, Robot Safety, Collaborative Robots
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Programmable Enzymatic Synthesis of Bioactive Compounds' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Enzymes are now established as highly selective biocatalysts in organic synthesis with the range of catalysts and reactions rapidly increasing through access to large protein databases and high-throughput molecular biology tools for biocatalyst engineering. The diversity of biocatalytic reactions is now at a stage where they can be linked in (chemo)-enzymatic reaction cascades, where two or more chemical and/or enzymatic reactions can be catalysed simultaneously generating de novo biosynthetic pathways for chemical synthesis not found in Nature. These reaction cascades have demonstrated important prior art, however they have been mostly limited to few steps and lack the complexity provided by the natural pharmacopeia. ProgrES aims to achieve a step-change by introducing unprecedented structural complexity into de novo pathways and by moving away from manual to automated, high-throughput cascade design and implementation. The proposal is to use a transdisciplinary approach that addresses three important bottlenecks: i. Identification of enzymatic reactions that allow early functionalisation and late stage diversification of the cascade toolkit to increase structural complexity, building on C-H activation mediated by monooxygenases, which are well established in our research group. ii. As diversity of targets increases, high resolution structural analysis of pathway intermediates and products becomes a bottleneck, which is addressed by high-throughput label free mass spectrometry based analytical tools that will match the demands on timescale and numbers. iii. In parallel, we will establish bioinformatics tools adapted from both chemical synthesis and biosynthesis, to allow programmable enzymatic synthesis for cascade design. As proof-of-concept and test bed for the Progr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Partial Discharge Management In Compact Insulation Systems'.

assistant: **Objectives**

This project aims to develop a clear methodology for the management of partial discharge in wound components (such as machines, brakes, actuators, solenoids) and connecting components (connectors and cables) used in aerospace systems in low pressure environments. Partial discharge is difficult to detect but can have a signfiicant impact on the lifetime of electrical systems. As such elimination of partial discharge is preferable and while this can be assessed in new insulation systems, no guidelines exist to help select test voltage requirements when ageing of insulation over the lifetime of the component is accounted for. Partial discharge elimination is not, however, always possible owing to the impact that increased insulation thicknesses can have on the volume of a component. As such partial discharge may have to be managed in a component subject to significant environmental stress throughout its lifetime.The project will deliver clear guidance on the design of components and the selection of insulation materials in a way that ensures the risk of partial discharge is minimised at the design stage. A significant test programme will then support the development of guidelines for the qualification of wound / connecting components and their test during production.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Leveraging the Environment of civil air TranSport with DOHOP' (2014-2020) under Horizon 2020.

assistant: **Objectives**

Nowadays there are many solutions for finding, comparing and booking flights. However, these solutions are based on pricing information, which can only offer pre-defined itineraries and does not disclose all the possibilities for connecting flights. This limitation is translated into fewer options for the users needing to connect flights (in some cases up to 30% of users cannot find a ticket for their route), thus restraining the benefits of airlines that are not selling all their tickets (only 70% of seat capacity is sold on some routes).Dohop is a mobile and web-based application that uses a unique approach; we use the schedule information provided by OAG , the most reputed airline schedules database, and pricing data from more than 400 sources. Our advanced algorithms process the data from OAG to build all possible alternatives for connecting two or more flights, thus providing more convenient or even hidden alternatives to users. Then, final prices are collected from our partner databases and shown in the app. This competitive advantage permits users to make their own connections between flights that were apparently not connected through other solutions – we call this quot;Self-Connectquot;. Besides the travellers, LETS provides benefits for: Low-cost carriers, using LETS as a support tool for creating interline networks without needing commercial agreements (around 800,000 € each per year) and increasing their sales around 2%-3%; and airports, optimising the traffic and PAX handling and thus increasing 2%-3% benefits by enabling interline connections in their operations with reduced costs (we estimate minimum benefits for airports of €8 million per year). Furthermore, savings in CO2 emissions are also boosted thanks to optimising the routes between airports.Through