RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Robust- and sustainable-by-design ultra-higH aspEct ratio wing and Airframe' (RHEA) targeting Horizon 2020.

assistant: **Abstract**

The efficiency gains offered by ultra-high aspect ratio wings are key to increase the sustainability of air travel as the volume of passengers continues to grow. However, a fully viable and deployable solution has not yet been proposed due to technological, certification and operational limits, which are mainly due to complex aeroelastic behaviour and constraints from both manufacturing methods and airport infrastructure. This project is centred around the idea that future-generation aircraft with ultra-high-aspect-ratio wings is conceivable with forward-looking technologies and physics-based multidisciplinary analysis and optimization approaches. Critically, RHEA will introduce a paradigm shift towards robust design methods, inherently built with a quantitative management of uncertainties in both operating conditions as well as model predictive capabilities. The project will also introduce a number of carefully selected technologies into the aero-structural design process of novel aircraft configurations. Multidisciplinary designs optimization of representative aircraft will address short-range, medium range and long-range missions.


**Keywords:** Ultra high aspect ratio wings, multidisciplinary design optimization, uncertainty based design optimization
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Unravelling host intestine-parasite interactions that define immune responses to whipworms' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Whipworms (Trichuris trichuira) are soil-transmitted helminths that infect about 700 million people in the tropicsand sub-tropics and cause the human disease, trichuriasis. Whipworms live preferentially in the cecum of theirhosts where they tunnel through epithelial cells and cause inflammation potentially resulting in colitis. Despiteextensive research, the role of whipworm interactions with epithelial and immune cells in triggering parasiteexpulsion remains unclear, hindering the development of anti-parasite therapies. The ultimate goal of my researchproposal is to investigate and understand this interaction in detail. To achieve this, I will use T. muris, a mousemodel of T. trichuira infection in humans. This research proposal has three key aims. First, to identify new parasiteand host genes that could interplay and modulate immunological outcomes. Second, to characterize the role of hostgenes in whipworm infection and immunity. Here, novel and known candidate mutations conferring susceptibilityto colitis identified through the Wellcome Trust Sanger Institute - Mouse Genetics Project will be targeted. Thus, Iwill challenge mutant mouse lines with T. muris and evaluate the influence of these mutations on anti-parasiteimmunity and expulsion. Finally, upon identification of key genes regulating the immune response to whipworms, Iwill explore the mechanism of action of selected genes and their effect on the parasite. For this, I will takeadvantage of the vast range of ‘omic’ technologies and facilities available at the WTSI. This project will generatenovel fundamental data on host-whipworms interactions and also support future efforts to control these parasites bythe identification of potential new therapeutic targets. Moreover, resulting knowledge of the parasiteimmunol
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Ion transport and signal transduction pathways contributing to salt tolerance in plants' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

The work outlined in this proposal will identify how processes at a range of different organizational levels (from genes to cellular events) contribute to salt tolerance of plants and whether their manipulation in transgenic plants can improve salinity tolerance. The project will use a number of different approaches to investigate the mechanisms and pathways that contribute to the tolerance of specific ion stresses when plants are grown in saline conditions, particularly processes involved in the regulation of cellular ionic composition. The hypothesis underlying the proposal is that regulation of cellular, particularly cytosolic, ion concentrations is central to salt tolerance and that this is regulation is achieved by modification of ion transport at the plasma membrane through changes in both the complement of transporters (gene expression) and their activity (biochemical regulation). The role of signal transduction and other regulatory pathways (phosphorylation/dephosphorylation) is a major focus both because our knowledge of how transport is regulated is rudimentary and because some Na'-sensitive enzymes may modulate inositol-based signalling pathways. The specific objectives are: 1. To understand the regulation of cytosolic and vacuolar ion concentrations in plants exposed to salinity, and to identify and characterise the membrane transport processes involved 2. To determine the effect of salinity on the regulation of ion transport, including changes in gene expression, biochemical modification of transporters, and regulation by small molecules or proteins 3. To study and elucidate the role of signal transduction pathways in salinity responses in plants, with particular emphasis on pathways already shown to be important in salinity responses of the yeast 4. To ide
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'New Horizons in C–H Activation: the ‘Real-World Molecules’ Challenge'.

assistant: **Innovation**

A 2018 joint report from pharma identified organic synthesis as one of the major bottlenecks in drug discovery today. In the highly competitive discovery environments, only fast-to-synthesise molecules are targeted, based mostly on five well-tested and proven synthetic methods. This approach has led to only a small portion of the chemical shape space being explored over the last decades and has been partly blamed for the recent low success rates in new drug development. The report emphasises the need for ideal tools such as late stage functionalisation, which would allow simply replacing any C‒H bond in a bioactive molecule with any desired functionality, thus greatly accelerating the synthesis of new candidates from a lead compound. However, the field of C‒H activation is significantly behind in achieving this aim: most biologically active molecules contain several polar and/or delicate functionalities (‘real world’ molecules), whereas most C‒H activation methods use harsh conditions, incompatible with delicate groups, and catalysts that tend to poison in the presence of polar groups.This ERC Advanced Grant addresses this major challenge by building a new tool-set of ruthenium catalysts that will finally be able to deliver late stage functionalisation on ‘real world’ molecules, thus allowing a new dawn for development not only of new drugs, but also of agrochemicals, aromatic based organic materials and associated areas. The project builds on a recent key mechanistic breakthrough by the PI's group on the operation of Ru-catalysts (Nature Chemistry 2018) that reveals a completely different pathway to catalyst design from that followed in the field in the last two decades. This new class of catalysts presents unprecedented high reactivity and compatibility with sensitive
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Micro-NanOSystems EUROpean NETwork pursuing the integration of NMS and ACC in ERA' in the context of a Sixth Framework call.

assistant: **Objectives**

MINO-EURONET is devoted to stimulating, encouraging and facilitating the participation of New Member States (NMS) and the Associated Candidate Countries (ACC) in the activities of IST. The project has a pan-European focus on one strategic objective in IST, namely micro- and nanosystems.The project will address the following objectives:(1) Revealing and promoting the research competences from NMS and ACC which are relevant for the development of the field of micro-nanosystems at the European scale;(2) Facilitating the participation of NMS and ACC organisations to EU programmes and other activities in the field of micro-nanosystems;(3) Performing extensive networking at the pan-European scale in the field of micro-nanosystems(4) Facilitating future research policy in micro-nanosystems in NMS/ACCThe project is put forward by 18 partners, including 8 Western research organisations, which are coordinators of 8 other big projects in FP6. This cluster of 8 consortia is totalling 159 different organisations, which provides sufficient critical mass for pan European networking. This cluster covers also a broad spectrum of technologies and applications, requiring broad multidisciplinary science and engineering and is displaying an exciting potential of cooperation for NMS and ACC.Activities are organized in four work packages devoted, respectively, to:(i) extensive networking, using an integrated communication platform;(ii) creation, maintenance and promotion of databases of researchers, research and industrial organisations, enhancing the visibility of potential partners from NMS and ACC and promoting participation to EU programmes;(iii) the organisation, with the same purpose of brokerage events and seminars, primarily in NMS and ACC, and also of Forums for policy makers in NMS/
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Evolving interactions in microbial communities' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Microbes play an important role in various aspects of our lives, from our own health to the health of our environment. In almost all of their natural habitats, microbes live in dense communities composed of different strains and species that interact with each other. As these microbes evolve, so do the interactions between them, which alters the functioning of the community as a whole.In this project, I propose to develop theoretical and experimental tools to study and control evolving interactions between cells and species living in microbial ecosystems. This will involve three main research objectives: first, we will couple theory and experiments to disentangle and characterise the social interactions between five bacterial species that make up an ecosystem used to degrade pollutants. Our second objective will be to use this knowledge to control this same ecosystem, by directing it toward increased productivity and stability. Finally, our third objective will be to “breed” novel communities from scratch using experimental evolution to promote cooperative interactions between community members and thereby increase productivity.This interdisciplinary and ambitious research will allow us to improve existing methods in pollution degradation, and to design new microbial communities for this and other purposes. More generally, our model system will provide an in-depth conceptual understanding of microbial ecosystems and their evolution, and the tools to investigate more complex microbial communities. My ultimate vision is to possess the technology to use microbial communities to degrade waste, generate efficient biofuels, and design customised treatments for intestinal diseases. This project promises to create the foundations needed to develop this technology, and open many
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Foreign policy governance in europe-research network modernising, widening and deepening research on a vital pillar of the eu' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

FORNET will establish and develop a European-wide research network on European Governance in the field of CFSP, based upon academic interaction, common methodological approaches and the use of new techniques of virtualisation. The establishment of a CFSP Watch" including a database, the listing of teacups academic, CFSP reports, the installation of a website, the elaboration of virtual study units, and a series of policy papers based upon workshops for discussing core issues of CFSP are foreseen. The CFSP reports will be based upon common methodological approach and lead to an analysis of a public discourse ounces in the EU. Dissemination will be undertaken mainly by publications, website and conferences, and be closely interrelated with the sustainability and evaluation dimensions."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Lead-cooled European Advanced Demonstration Reactor' (LEADER), addressing dissemination and exploitation.

assistant: **Impact**

The LEADER proposal deals with the development to a conceptual level of a Lead Fast Reactor Industrial size plant and of a scaled demonstrator of the LFR technology. The proposal is based on previous achievements obtained during the 6th FP of the EU in the ELSY project but takes into account the indications emerged from the European Strategic Research Agenda as well as the main goals of the European Industrial Initiative on Fission. As a consequence the project is strongly committed to the conceptual design of a scaled/pilot plant to be constructed in the relatively short term. The focus of the first part of activity will be the resolutions of the key issues emerged in the frame of the ELSY project to reach a new reference reactor configuration. This updated reactor configuration of an industrial size LFR will be used to design a low cost and fully representative scaled down prototype of a suitable size. The project foresee an important involvement of End-Users and Safety Authorities from the beginning of the design process to help the plant conception and to assure high safety standards. Education and Training activities are included in a specific work package where European Universities are directly involved with the aim to grow-up the future nuclear energy designer. The LEADER projects takes strongly into account the others already proposed or on-going EU projects. All projects dedicated to R&D and material developments, projects dedicated to the development of ADS systems for transmutation or related to the development of fast reactors (VELLA, CDT, CP-ESFR, GETMAT, FAIRFUELS, ACSEPT, EUFRAT, F-BRIDGE, ACSEPT, ACTINET-I3, THINS) have strong synergies with LEADER toward the development of a Lead cooled fast reactor system. The project Partners are convinced that foste
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Multiscale investigation of mineral biosignatures with novel and integrated synchrotron approaches' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Microorganism are known to trigger or mediate the formation and transformation of different minerals, such as carbonates and silicates. Microbial-mineral interactions potentially generate chemical and structural characteristics in biominerals, which can be preserved deep in time as mineral biosignatures and be explored in the search for life on early Earth or Mars. We plan to investigate signatures of life in Archean, Proterozoic and modern sedimentary structures by integrating chemical, morphological and structural information using a pioneering approach based in laboratory and synchrotron-based advanced imaging methods. Our approach will integrate state-of-art laboratory characterization of geochemistry and mineralogy with mineral and crystallographic textures and ultrastructure in 2D and 3D. It will shed light into the understanding on the biomineralization processes of microbial carbonates and cherts, and provide biological interpretations of relevance to studies on early life on Earth and Mars contexts.


**Keywords:** geomicrobiology, microbialites, biosignatures, synchrotron, X-ray imaging, early life
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'StarLink: The World's First Intelligent Vacuum Pump System' (StarLink).

assistant: **Concept**

Vacuum pumps are used in thousands of industrial applications, playing a vital role in food processing, semiconductors, chemicals, pharmaceuticals and many other manufacturing and assembly processes. However, today’s pumps are currently unable to provide any type of insights that could help users anticipate a pump malfunction, plan maintenance procedures or setting the adjustments. Pump malfunctions or breakdowns, due to unplanned maintenance or improper settings, cost millions of euros in lost revenues every year as production and logistic lines lie idle waiting for pumps to be fixed, and when they are not optimized their productivity decrease or their energy consumption go up. But now, DVP, a vacuum pump manufacturer, has developed the solution to these challenges through StarLink, the world’s first intelligent vacuum pump system. StarLink is a patent-pending system that uses data analytics and machine learning to identify pump malfunctions before they happen, propose actions to be taken, and automatically adjust the operation parameters if the problem relates to the setting. This will reduce pump downtime-related costs by 30%, increase their productivity by 50% and make easier the operation manager tasks.  The combination of our deep knowledge of vacuum pumps needs with the machine learning expertise of the university of Ferrara will create the most intelligent device to improve the competitiveness of European companies. Additionally, StarLink will contribute to DVP’s growth in terms of employees and product portfolio since we will be able to offer a wider range of products and services related to vacuum pumps, which will allow us to enter new markets and sell more units. By 2023, it will generate €3M in yearly revenue with net profits of €2M to our company.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'TELEMATICS SERVICES FOR ISLANDS'.

assistant: **Concept**

The role of telematics in promoting the quality of life for isolated island communities in Europe will be the focus of TELE-INSULA. Project analysis of community needs will cover services such as health, transport and training. An embryonic island services network will enable pooling of user experience and practical work with telematics tools. Applications for a fully-fledged network will be identified and some of them validated and tested for economy and acceptability. Computer conferencing and kiosk systems will be among the technologies considered by the project which seeks to improve links between islands and the larger economic systems to which they belong.Islands populations live their life isolated from the larger communities to which they belong. The Tele-insula Partners believe that telematics can help to break this isolation. The aim of the Project is therefore to identify practical ways in which telematics can contribute to the quality of island life.The Project will analyze the general needs of island communities and the specific needs of the six islands or archipelagoes partipating in the Project. Special attention will be paid to the fields of administratative services, health, tourism, transport, training and tele-work. An embryonic European Island Services Network will be created, allowing the pooling of user experience and giving decision-makers experience in the use of telematics tools. On the basis of the needs analysis the Project will identify and specify a range of services to be implemented in a future full-scale network. A subset of these services will be taken to the validation stage (verification and demonstration). Each service selected for validation will be tested in at least one community. The technology used will be based on standards wide