RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Intermetallic Phase Heterostructured Circular Aluminium Alloys' (HETEROCIRCAL), addressing dissemination and exploitation.

assistant: **Impact**

A tenet in metallurgy is that the purer metals and alloys are, the better are their properties. However, as recycling in material production increases in importance, so do impurity levels. In aluminium the consequences are particularly harmful because the solubility of most elements in aluminium is very small, resulting in the formation of brittle intermetallic phases. Moreover, once impurities have entered aluminium, it is nearly impossible to remove them. The HETEROCIRCAL project aims to break the paradigm of „harmful“ impurities.HETEROCIRCAL’s main contribution will be to develop a new, ground-breaking class of upcycled materials that can tolerate high levels of impurities. We will achieve this goal by designing intermetallic phase containing heterostructured alloys where previously detrimental intermetallic phases become impurity sinks – sinks which also form a novel heterostructure which features an excellent trade-off between strength and ductility. Here we aim to reverse the common view of primary intermetallic phases in aluminium wrought alloys, and to extend their admitted volume fraction to unexplored regions. Our preliminary work gives evidence that structures with such properties are in fact possible.The main challenge will be to develop viable means of creating beneficial intermetallic phase heterostructures, that are applicable in large-scale. We will address it by manipulating intermetallic phases during solidification and solid-state processing and applying a high-throughput method. HETEROCIRCAL’s aim is also to gain insights into the formation of intermetallic phases at high resolution and their role in the novel heterostructures. The project will meet the enormous challenge of creating sustainable aluminium alloys for a future circular economy, and red
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The Challenges of Return Migration in Africa in the Age of Complex Emergencies: Comparing Multilevel Governance Systems in Ethiopia and Nigeria' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

This project fills the research and policy gaps in the understudied phenomenon of return migration in Africa, against the backdrop of recent migration 'crisis' in Europe, the increasing securitization of the EU's external borders to curb irregular migration, and the complex emergencies faced by migrants transiting through Libya to Europe. It uses a multilevel governance (MLG) framework to explore the decision-making processes/politics of returning stranded migrants from Libya to their countries of origin in the context of interdependence between governmental actors and nongovernmental organizations at the local, national, regional, and global levels. The few previous studies on return migration in Africa have given relatively little attention to these critical linkages and their reciprocal constructions, in the integrated manner of the MLG approach. The project explores the effects of MLG dynamics on return migrants' reintegration, and the effects of institutional complexity on intergovernmental coordination and policy coherence. The empirical study focuses on Ethiopia and Nigeria, two key priority countries under the EU-IOM Joint Initiative for Migrant Protection and Reintegration, which have served as major countries of origin for migrants and which have witnessed the return of migrants from Libya. The project uses structured focused comparison and process tracing research design, and qualitative methods involving in-depth interviews with returnees and key informants, and document analysis. Consistent with the understanding of MLG as a complex interaction between multiple configurations of actors with divergent interests, ideas and power resources, this study will analyze the mechanisms through which multiple governance authorities interact to shape return migration p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Curating the Ephemeral: Practices of Engagement and Display in Contemporary Art' (CTE) under Seventh Framework.

assistant: **Objectives**

A training-through-research project whose aim is to substantially enhance and complement the experienced researcher’s established profile as a respected writer with specialisms in theatre, performance and art theory, by creating a strong profile in curatorial practice (and strategy) within the visual arts sector. The project stages a sustained investigation of diverse curatorial approaches within and outside international art institutions, under the expert supervision of Carol Becker (Professor and Dean, School of the Arts, Columbia University, NYC). Becker is renowned for her work on radical art practices, art institutions, globalization and the politics of contemporary cultural production. CTE takes place in the context of a proliferation of contemporary art practices that challenge the objecthood, permanence and material status of the artwork. It examines recent tendencies toward socially engaged, processual and relational artworks; the re-valuation of dance and performance art within museums; and the conditions of display, reception and archival presence now given to such work by art’s institutions and arbiters. The project will move through the close examination and realization of curatorial tactics in participating major international art institutions in America and Europe as well as the observation and analysis of work by numerous independent curators. Consolidating and articulating the curatorial knowledges acquired through sustained cross-cultural and cross-sectoral training experiences, I will produce a landmark publication alongside public-facing outreach events within participating institutions. The international dimension of this research will benefit European art and performance cultures and institutions, by transferring knowledge of historically marginali
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Development and Manufacturing of a Smart AFC Drive and Control System' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The project FloCoS will focus on an integrated flow control actuator driving system taking into account the specific requirements of piezoelectrically driven Synthetic Jet Actuators. The system will be divided into two different main parts: The amplifier unit on the one hand and the control part on the other hand. For making measurement values available which will be used for closed-loop control of the actuator, a dedicated measurement circuit will be developed and optimized for this specific application. A highly integrated and miniaturized electronic module for fluidic AFC actuators will be the output of this project. FloCoS will not only provide smart power amplifier solutions, but also efficient solutions. State-of-the-art power recovery technologies will be used to minimize the needed power for driving the piezoelectric elements. For the addressed application scenarios, e.g. the test of actuators in large scale wind tunnel test studies, there are special requirements for remote access and control for the system. For the test of the actuators as well as the aerodynamic concepts, the actuators have to be driven in WT/T environment, where control computers and power supply connectors may be far away from the point of action. FloCoS will provide remote access to all system parameters with an advanced monitoring and logging functionality.The requested number of actuators suggests that there is a short term plan to test the actuators at a specific region in the wing, e.g. pylon-wing junction or outer wing. The integration aspects for these regions will demand special concepts for miniaturized solutions. The system itself will be encapsulated to comply with all harsh environmental requirements which are applied to the system in relevant environmental conditions. The confo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Interspecies endotheliarization for organ xenotransplantation', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Organ transplantation is an efficient approach or remedying end-life diseases that cannot be treated by other methods. Nevertheless, the available organs do not cover the clinical demand. As an alternative to the transplantation human organs, the xenotransplantation of animals’ organs has been proposed. Unfortunately, despite the big effort of the last decades, organs are severely rejected upon xenotransplantation, the endothelial cells (ECs) playing a fundamental role in this process. ECs are the first target of the immune system reactions; moreover molecular incompatibilities between host’s coagulation system and the exogenous ECs enhance thrombotic microangiopathy, which rapidly destroys the xenotransplanted organ. Therefore, we hypothesize that endotheliarization of the donor’s organs with cells of the future host may have an important effect on the rejection upon xenotransplantation. To prove this hypothesis, we propose to generate (mouse-ratEC) chimera by inter-species blastocyst complementation assay, which recently has been described effective for the generation of chimera animals between different species, and to determine the degree of rejection against the hearts of this chimera, once heterotopically xenotransplanted in rat. This project, which is based on mouse and rat systems, aims to deliver a proof of principle that, if obtained, will be further developed in clinically more relevant big animal models.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Smart Cultural Tourism as a Driver of Sustainable Development of European Regions' to be submitted under Horizon 2020.

assistant: **Abstract**

SmartCulTour aims to support regional development in European regions, with special attention to rural peripheries and the urban fringe, through sustainable cultural tourism. The project redefines cultural tourism through a contemporary lens and provides a comprehensive measurement framework for supply, demand and impacts. In order to support knowledge-led destination management, a decision-support system (DSS) will be developed for wide-scale monitoring purposes across European regions. The DSS will synthesize both traditional and non-traditional data sources, the latter particularly related to big data analytics, thereby assisting smart regional development. Besides a contribution to conceptual development and cultural tourism measurement, the main objective of SmartCulTour relates to the facilitation of community-led rural development through field experimentation in 6 living labs. Prior to these living labs, a comprehensive desk research will identify significant sustainable cultural tourism policies, their impacts and critical success factors. These best cases will inspire a series of possible local interventions. Within the living labs, novel creative approaches to stakeholder engagement are tested, notably arts-based methods, serious games, and service design which will help to provide local context and support. A toolkit will be designed to help destinations implement local actions towards sustainable cultural tourism development. SmartCulTour will therefore contribute to theory development, empirical validation of best practices within a living labs setting, and procedural development, particularly by providing European regions with a set of strategies to optimally engage with stakeholders and co-create sustainable cultural tourism experiences.


**Keywords:**
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Chagas' disease - Inhibitor discovery and optimization for Trypanosoma cruzi trans-sialidase' under Seventh Framework.

assistant: **Concept**

This proposal focus on finding new potential lead compounds to inhibit the trans-sialidase of Trypanosoma cruzi, as a step towards finding a drug against Chagas’ disease. A new high through-put enzyme assay will be used to scan a large library of small molecules and in combination with in silico pharmacophoric modelling this is expected to provide new types of scaffolds as well as identifying important functionalities in the ligand. Based on the obtained information a set of ligands will be designed. These ligands will be synthesised and further evaluated through the enzyme assay, kinetic and thermodynamical studies as well as structural studies. In an iterative optimization, these tools will be combined to obtain future generations of inhibitory ligands.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Towards a Remotely sensed estimation of the Photosynthetic Energy balance' under Horizon 2020.

assistant: **Concept**

Photosynthesis is the largest flux in the global carbon cycle and therefore of utmost importance for climate change and agricultural research. Radiometric sensors mounted on satellites and airplanes are the only technology providing spatially explicit information about vegetation activity and health at regional to global scale. In particular, the recent availability of remotely sensed sun-induced fluorescence (F), which is directly coupled to the photosynthetic process, opens new perspectives in estimating plant photosynthesis at larger scales. Considering the recently selected satellite Fluorescence Explorer (FLEX) mission by the European Space Agency (ESA) that will launch in 2022, new methods have to be developed to optimally use the F signal for an improved global estimation of photosynthesis. “ReSPEc” aims to develop new algorithms to improve the estimation of plant photosynthesis at ecosystem to regional scale (gross primary production; GPP) by assessing the photosynthetic energy balance of the light reactions from remote sensing platforms. To achieve this goal an open-field manipulation experiment will be setup to develop and test a semi-mechanistic model that links novel and established optical signals with gas-exchange measurements to assess the photosynthetic energy balance on leaf and plant scale. The semi-mechanistic model will then be applied to a pre-existing datasets of airborne measured F and vegetation reflectance to estimate GPP on ecosystem scale. Results will be compared and validated with eddy-covariance-based estimates of GPP. The outcome of this project will contribute to a better understanding of the photosynthetic energy balance on leaf-, plant- and ecosystem scale, which in turn allows an improved estimation of GPP. By ensuring that all necessa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Functional role of Epithelial–to–Mesenchymal Transition in the pathogenesis of Inflammatory Bowel Disease' (INFLEMT) targeting Horizon 2020.

assistant: **Abstract**

Inflammatory bowel disease (IBD) defines a group of chronic inflammatory disorders of the digestive tract, with ulcerative colitis and Crohn’s disease being its two major clinical manifestations, affecting 2.5 million people in Europe. The high prevalence of IBD in Europe and the multiple clinical challenges associated with a significant degree of unresponsiveness to anti-inflammatory therapies and development of complications requiring surgical intervention demand a deeper understanding of the cellular and molecular mechanisms underpinning IBD.This project aims to understand the role of the process termed Epithelial–to–Mesenchymal Transition (EMT), an embryonic cellular trans-differentiation program re-launched in many pathological conditions, in the pathogenesis of IBD. EMT has in fact been detected in the inflamed intestinal mucosa and surrounding fibrotic areas of IBD patients and experimental models of colitis, however whether EMT functionally contributes to the pathogenesis of IBD is poorly understood.The INFLEMT project aims to: 1) profile EMT in human IBD to identify its cellular features and correlation with the disease stage; 2) elucidate the impact of EMT on the integrity, functionality and regenerative capacity of the intestinal epithelial barrier; 3) explore the effects of EMT on fibrosis development and modulation of the immune response to assess its role in sustaining the chronic intestinal disease. These objectives will be pursued by utilizing patient-derived biopsies as well as novel mouse models to manipulate EMT in the intestinal epithelium. Comprehensive analysis, including RNA-sequencing and multispectral imaging, of the involved cellular and microenvironmental components (epithelial barrier, immune cells, fibroblasts) will be performed in acute and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Urban Terrorism in Europe (2004-2019): Remembering, Imagining, and Anticipating Violence' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Since 2004, public spaces in European cities have been hit by more than ten major terrorist attacks, killing hundreds of people and injuring thousands. Whilst trying to come to terms with recent acts of urban terrorism, governments, security agencies, and local communities are bracing themselves for further attacks. UrbTerr will offer the first in-depth comparative analysis of memory discourses and responses to recent acts of urban terrorism in four European countries that have suffered particularly as a result of this wave of violence: Spain, the UK, France, and Germany. Drawing on concepts and methods from memory studies, cultural studies, feminist theory and anthropology, UrbTerr will document and analyse a range of voices in contemporary debates on urban terrorism in Europe and problematise the narrow concept of imagination and creativity underpinning recent counter-terrorism measures and a great part of the academic literature on this subject. It will: (1) analyse the collective forms of forgetting, remembering, and imagining that have shaped urban spaces in the four countries after recent terrorist attacks; (2) develop a new materialist approach to terrorism and use this framework to critically assess policies and material security infrastructures that were created in response to these attacks at a local and European level; (3) use performance art as a creative tool to develop and experiment with alternative forms of remembering and different visions of the future. Outputs of the project will include a website with footage of interviews with city residents, politicians, architects, political activists, and other key actors, as well as other resources for terrorism research, two academic monographs, articles in peer-reviewed journals, a co-edited volume, two PhD th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Role of the SWI/SNF complex in the Androgen Receptor cistrome regulation' (RegARcis) targeting Horizon 2020.

assistant: **Abstract**

The significance of epigenetic deregulation is a very hot topic in current prostate cancer (PC) research. New mutations have been identified in several epigenetic regulators known for their interaction with the AR. In fact, the role of chromatin remodeling factors facilitating enhancer-promoter cooperation in the formation of the AR transcriptional complex has long been demonstrated. Accordingly, the marked redistribution of AR binding sites (cistrome) during tumorigenesis is arguably the most recurrent genetic or epigenetic alterations in PC. Thus, this MCSA project aims at elucidating the role of the SWI/SNF chromatin-remodeling complex in the emergence of resistance to anti-AR signaling inhibitors. This is of utmost importance as resistance to AR signaling inhibition is arguably the principle hallmark of lethal prostate cancer. To this end, I aim at (i) investigating the SWI/SNF dependent chromatin accessibility and AR cistrome; and at (ii) assessing the actionability of SWI/SNF interacting partners in castration resistance prostate cancer (CRPC). In short, this MSCA proposal will help to define the repertoire of SWI/SNF coregulators in CRPC and to determine the extent of AR cistrome remodeling to envision new therapeutic strategies and help predict treatment response.