RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Thermo-adjustable endoscope heater system to solve problems of fogging during surgical interventions' (EHS), addressing dissemination and exploitation.

assistant: **Impact**

Maintenance of optimal vision during minimally invasive surgery is crucial to maintaining operative awareness, efficiency and safety. Hampered vision is commonly caused by laparoscopic lens fogging (LLF) which has prompted the development of various anti-fogging fluids and warming devices. Numerous tricks have been proposed to overcome this issue, such as heating the scope into a sterile thermos flask filled with hot water, or using one of the commercially available antifogging solutions. However, whether one method is superior to another remains elusive. As most surgeons know, none of these tips are totally efficient, as they don’t treat the cause: the temperature difference.Taking into account this need, Noruco has developed EHS, a thermo-adjustable system by microcontroller, which is implemented in the manufacturing process of the rigid endoscope focused on laparoscopy. The technology enables the selfmodulation of the temperature of the endoscope within the different conditions during the surgery, avoiding the 100% of laparoscopic fogging. With the adoption of EHS surgeons get a clear field of vision avoiding continues repetitions of extraction and insertion of the endoscope in the body during the intervention. In this way the risks of the patients are reduced with a more efficient and shorter duration procedure. EHS also represents an alternative that meets sustainability criteria by reducing energy costs and eliminating much of the waste currently generated by this procedure. Therefore, this innovation will disrupt the laparoscopic device market by enhancing safety and effectiveness without introducing new components that could complicate surgical procedures.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Intelligent Biomaterial Systems for Cardiovascular Tissue Repair' (BIOSYS) targeting Sixth Framework.

assistant: **Abstract**

Cardiovascular diseases are the most frequent cause of mortality in Europe. Concomitant the main age of the European population will increase significantly in the next decades. To prevent the collapse of the health care system as a result of the unpayable clinic cost, new strategies have to be found. Tissue engineering is such a promising strategy to compensate the disadvantages of conventional cardiovascular prostheses. A tissue replacement, engineered from a patients own cells, which can grow and replace the defective tissue, is here the superlative answer. Therefore the objective of the BioSys project is to develop new intelligent biomaterial systems. Starting from common polymers, a biocompatible fibre with controllable degradation will be developed. The fibre will be tested regarding degradation and biocompatibility. Required surface modifications will be carried out, focusing on the improvement of biocompatibility. Different types of 3D-textile scaffolds will be designed and produced. As example for evaluation and implementation of the new intelligent biomaterial, cardiovascular implants will be evaluated and tissue engineered. The developed biomaterial will be the first material with controllable biodegradability and improved biocompability. A material with these properties is not yet available in Europe or in other countries. European researchers will be the first to develop and use this kind of intelligent biomaterial. BioSys demonstrates the competitiveness of European life science research. The results of the project could be transferred to other medical fields for a long term innovation. The enhancement of knowledge in Tissue Engineering and the development of new biomaterial will be a huge contribution to increase the living quality of the population of the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Redox-mediated hybrid zinc-air flow batteries for more resilient integrated power systems' (ReZilient) under Horizon Europe.

assistant: **Objectives**

The penetration of renewable energies into the electric grid increases the demand for energy storage to ensure reliable power supply, grid resiliency, and cost reductions. Long-duration and long-term energy storage (LDES and LTES) can bridge the intermittency of renewable sources and reduce the risks incurred by diminished fossil-fuel baseload generation. Electrochemical energy storage (EES), or Li-ion batteries (LIBs), are considered for short-duration energy storage (4-6 hours). When talking about seasonal storage, hydrogen storage is usually the preferable option.   The goal of ReZilient is to fill the gap between short-term EES and long-term hydrogen storage by developing and demonstrating at lab-scale (0.5-1.5kW/6kWh) a completely new Zn-air flow battery technology. The estimated capital cost for large-scale deployment is approximately 80 €/kWh, with a levelized-cost-of-storage <0.5 €/kWh/cycle (based on 100 kW/1000 kWh system, 1 week discharge duration). A disruptive redox-mediated strategy for enhanced charge transfer processes is employed with the goal of confining the Zn/Zn2+ redox reaction in the negative reservoir (filled with a semi-solid zinc solution) and eliminating the electroplating process inside the cell (no dendrites) to improve battery lifetime. This will allow discharge times beyond days, contrary to conventional zinc-based batteries where long discharge is hampered by the formation of a cm-thick zinc anode.  If successful, the technology has disruptive potential in terms of both extremely low levelized-cost-of-storage, extended storage time, recyclability, and use of non-critical-raw-materials. A pilot concept design of the cell will be conceived after demonstration of the technology. The output of this design will lead to an update of the busines
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Sustainability of environmental aquaculture feeds workshop' (1998-2002), addressing dissemination and exploitation.

assistant: **Impact**

Aquaculture is often promoted as a solution to declining supplies from wild capture fisheries, but it remains reliant on capture fisheries for feed in the form of fishmeal and fish oil. This reliance has caused many to question aquaculture's sustainability. The debate has become polarised and controversial.The SEAFeeds workshop will address these questions, and provide an informed and objective synthesis to serve as the basis for rational policy development and further research. The workshop will draw together key stakeholders in European aquaculture, feed manufacture, scientific research, and environmental management. Participation in the workshop is supplemented by much broader representation in a pre-workshop electronic forum and a post-workshop electronic de-brief. The project will generate broadly agreed conclusions and recommendations including agreed sustainability criteria for aquaculture feeds.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Development of a general strategy for the conversion of pyridines into benzonitriles'.

assistant: **Objectives**

Bioisosteric replacement is crucial to drug discovery. However, substituting a central core ring structure generally requires de novo synthetic sequences due to the lack of “ring-replacing” strategies that can be used at a late-stage.This project will focus on finding a solution to the challenge of converting pyridines into benzonitriles. This is a desirable “ring replacement” in medicinal chemist and benzonitriles can mimic pyridines' properties and are effective bioisosteres. However, current methods to convert pyridines to benzonitriles are limited to de novo synthetic approaches.This project seeks to develop a novel strategy converting pyridines into benzonitriles. This will be achieved in just three steps by (1) pyridine N-oxidation, followed by (2) photochemical deconstruction into a nitrile-containing linear diene, which (3) is primed for Diels-Alder cycloaddition to reconstruct the aromatic benzonitrile. This strategy will constitute a divergent platform for the diversification of high-value pyridine products and also a novel retrosynthetic tactic for the reparation of complex benzonitriles. This research squarely fits within a recent new research direction the Leonori group where photochemistry is used to alter the structure of aromatic molecules.The completion of such an innovative and ambitious project at RWTH Aachen University will be facilitated by generating, transferring, sharing and disseminating knowledge, and will enhance the Researcher future career following the training plan envisioned.


**Keywords:** photochemistry, Diels-Alder cycloaddition, dearomative ring-opening
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'How to help the hive? Incidence and impact of heritable microbes on bee health' (BeeSymOverSpace) under Horizon 2020.

assistant: **Objectives**

Honey bees provide both economic and societal benefits, from the honey and other commodities that they produce to the pollination services they provide. The loss of honey bee colonies and the current threats to their health are of considerable concern to bee-keepers and biologists alike. This project seeks to examine how a particular aspect of honey bee biology – the symbiotic microbiome – impacts upon honey bee health. Studies in other systems reveal heritable microbes as important modulators of disease susceptibility. This project will utilize the extensive network of bee samples across the US and UK to establish geographical patterns of heritable microbe presence in bees, and links to apiculture practice. It will then use state of the art transcriptomic and genomic approaches to establish the links between Arsenophonus, a heritable symbiont known in bees, and bee health. It will then, combine with professional agencies responsible for bee health to use these results to modify apiculture practice to establish better bee husbandry.  Aside the research science completed, the project will train an EU scientist in state of the art genomic technologies and translation from discovery to applied science. It will further transfer the training gained to EU hosts, both in discovery science and application.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Social determinants and ecological impacts of seed transmission systems in African root and tuber crops, and their implications for resilience of smallholder farming systems' (KINSEED) under Seventh Framework.

assistant: **Objectives**

Understanding the processes by which smallholder farmers in developing countries increase or renew crop diversity, and how they maintain this diversity by ensuring the transmission of their technical and ecological knowledge through the generations, is essential for tackling food insecurity whilst at the same time conserving agricultural biodiversity. The KINSEED project focuses on seed transmission systems as a determining factor of the adaptive capacity of smallholder farming societies in a context of global changes, in particular climate change. Seed transmission systems are defined as the set of social norms and rules that govern the generational transmission of ‘seeds’ (here understood in the sense of propagules i.e., any material―true seeds, tubers, rhizomes, or stem cuttings―that are used for propagating crop varieties). The project will investigate the link between kinship systems and seed transmission systems and their role in structuring crop diversity and accessibility at local and regional levels. Because of its social dimension and intricate relation with traditional economic systems, seed transmission is an essential component of social-ecological systems yet it has seldom been studied, particularly in the context of resilience. The aims of this project are threefold: 1) To examine the relationship between seed exchanges and marriage exchanges and analyse the effects of seed transmission on the dynamics of crop diversity at local and regional levels; 2) To investigate the social and biological implications of global changes for smallholder farming societies and examine whether seed transmission systems may provide an opportunity for capacity-building or act as a social barrier to adaptation actions aiming at enhancing smallholder farming systems’ resilienc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Hanf als baumaterial fur den niedrig-energie-holzhausbau' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Hemp as building-material for Energie- efficient wooden houses In the last time the use of hemp- seeds in the pharmaceutic- and food- industry has increased. So the rest of the plant, valuable fibres, is not used. The use of hemp- fibres in housing applications is new. However it is known from other applications such as paper production that the hemp-fibres process very good mechanic qualities. The following 2 applications for hemp as an environmentally safe building- material will be in the focus of this research proposal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Dynamic Ions under Nano-Confinement for Porous Membranes with Ultrafast Gas Permeation Control' (DYONCON), addressing dissemination and exploitation.

assistant: **Impact**

Transport phenomena of molecules and ions inside porous materials are paramount in various fields, ranging from energy storage and transformation to molecular separation. In advanced energy storage devices, like supercapacitors and batteries, ions are confined in small pores. Nanoconfinement effects change the ion properties and enhance the performance, vital for saving resources and energy. So far, the static properties of nanoconfined ions are thoroughly studied but there is little known about the dynamic properties of ions in nanopores, mainly attributed to the lack of suitable experimental model systems. In DYONCON, the dynamic properties of nanoconfined ions will be explored by using well-defined, tunable model systems. This is realized by combining two exclusive material classes: ionic liquids, ILs, which are room-temperature molten salts of organic molecules, and films of metal-organic frameworks, MOFs. MOF films provide the variable, crystalline, scaffold-like container for the ion confinement. An applied electric field will act on the nanoconfined ILs, causing its directed movements. Controlling the dynamic properties of the nanoconfined ions will lead to myriad advances of safety and efficiency concerns, including enhanced charging rates of energy storage devices.In a radical new approach, DYONCON will also show that nanoconfined ions provide unprecedented functionalities. Based on the functional uniformity of IL@MOF membranes, the nano-level control of the confined ions will be used to regulate macroscopic gas fluxes with ultrafast switching rates, orders of magnitude faster than conventional gas valves.DYONCON aims to enhance the potentials of electrochemical technologies in energy storage, in sensors and in iontronics. The benefits of DYONCON will not only
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'From fragments to high affinity binders interfacing integrated structural biology, medicinal chemistry and artificial intelligence'.

assistant: **Objectives**

Fragment-Screen will develop innovative instrumentation, workflows and experimental and computational methodologies for fragment-based drug discovery (FBDD) enabling access to early phase structure-based drug discovery for all biological targets and for scientists both in industry and academia. The established workflows will use structural biology insights and associated data to feed artificial intelligence (AI) methodology to guide medicinal chemistry in drug development. Fragment-Screen brings together scientists from four ESFRI Landmark research infrastructures (RIs): ESRF (the European synchrotron) and the distributed RIs EU-OPENSCREEN ERIC (medicinal chemistry), ELIXIR (data resources for life science) under the coordination of Instruct-ERIC (integrated structural biology) and seven industry partners in scientific instrumentation and computational and AI sectors including SMEs to remove crucial bottlenecks in early phase drug discovery. The new instrumentation and workflows will be available at European RIs, while the new instruments will be commercialised to increase the technological competitiveness of European industry in drug design and the attractiveness of structural biology RIs for the pharmaceutical and biotech sectors. Fragment-Screen will implement open science approaches in early drug discovery to maximise the impact of screening campaigns. Generated data will be made accessible so that iterative cycles applying AI will improve response times for drug discovery. We will create a framework for the objective and independent evaluation of AI in drug design to identify critical developments in this thriving research field. Methodologies for rigorous cross-validation will be established through demonstrator and pilot studies and results will be disseminated t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Multizonal scaffold system based on collagen and copper doped mesoporous bioactive glass microspheres for dual release of growth factors for application as wound dressing material.'.

assistant: **Innovation**

This project is an attempt to develop an effective bioactive wound dressing for the treatment of chronic non-healing wounds that until now depict a major challenge and financial burden to healthcare providers. We propose a zonal, multifunctional scaffold based on collagen (COL) and copper-doped mesoporous bioactive glass (Cu-MBG) serving as release system for vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF-BB). The degradable scaffold system is expected to accelerate the wound healing process due to synergy of angiogenetic, bioactivity, and antimicrobial characteristics. This will be the first attempt to create a zonal COL-MBG scaffold system with release of three functional molecules, of which PDGF-BB has not previously been incorporated to MBG. Zonal design enables designed consecutive release profiles, e.g. immediate PDGF-BB from the outer layer and delayed VEGF release from the inner layer of the scaffold. The structure of the scaffold as well as distribution of specific components and their functionality will be characterized using innovative in vitro models including cell culture tests. The experienced researcher Dr. Nganga defended her PhD-thesis 2013 at University of Turku, Finland and has authored six original research papers. She has profound experience in biomaterials research based on involvement in cutting edge research at Universities in Germany, Finland and Italy. The beneficiary the Department of Materials Science and Engineering and the Institute of Biomaterials at University of Erlangen-Nuremberg is a well-respected international player in biomaterials research with extensive experience of hosting foreign researchers, including MC fellows. Prof. A.R. Boccaccini is a highly recognised researcher in the biomaterials fie