RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'EXTENDING QUALITY URBAN SERVICE FOR ADDED-VALUE LIVING USING INTERACTIVE TELEMATIC SYSTEMS' under Fourth Framework.

assistant: **Concept**

EQUALITY will show how under-privileged urban people can use value-added multimedia systems for support from integrated social, health and local authority teleservices. Independent initial validation at the six EU city sites will involve quite large-scale trials with end-user groups, and mature technologies such as the World Wide Web. Each of these multi-purpose delivery mechanisms will then assimilate applications from the other partners. The project will demonstrate that cities can share their teleservice provision economically, and use special conversion tools as prototypes for electronic data interchange and similar systems.The cities of Den Haag, Helsinki, Leeds, Livorno, Newcastle Upon Tyne and Rome have combined their efforts to demonstrate how the quality of life of the less-favoured European citizen in urban areas, could be improved by providing integrated social, health and local civic teleservices, using generic multi-media telematics value-added delivery systems.During the first stage of the project 6 demonstrators will be implemented and validated during relatively large scale trials with end-user groups (20 - 50 per site for dedicated applications and 500 - 5000 for generic services). These will use mature technologies such as TELETEXT and the World Wide Web (WWW). Network owners, suppliers and research organisations developing services at the leading edge of technology such as interactive cable TV (CATV) and Asynchronous Transfer Mode (ATM) service networks will participate in the trials. At the end of the project these 6 multi-purpose delivery mechanisms will be enriched by migrated applications from the partner cities.The outputs of EQUALITY are twofold.First is the demonstration across the union that cities can begin to migrate their systems to teleser
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Plug and Produce Joint Interface Modules' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

PoPJIM identifies critical performance limiting problems in machine tool design and use. The project idea is based on two crucial innovative solutions: i) replacing conventional machine tool structural joint interfaces by a self configuring and optimising mechatronic module called Joint Interface Module, JIM, made of functional materials and ii) a wireless network consisting of these modules and a machining process proxy to enable adaptive control and plug and produce capability to the JIMs. JIMs are designed to adapt the dynamic behaviour of a machine-tool during its interaction with the cutting process. Traditionally dynamic instability in a machining process is controlled by tuning the process parameters to match with the inherent dynamic characteristics of the machine tool structure which often results in lowering the rates of production. The novelty of the JIM concept is instead of changing the process parameters; dynamic stiffness of the machine tool is controlled to maintain the process stability. The Distributed Wireless Configuration and Control Network enables plug and produce capability and decentralised control of JIMs through a wireless communication network. This development is essential for achieving modularity and plug and produce capability for JIM-based machine tools. Controlled design of JIMs allows the dynamic behaviour of the machine tool to be predictable with more accuracy. The mechatronic design of the JIM includes an integrated control system and embedded intelligence which enable to be self-adaptive for optimising the dynamic stiffness within its design range during a machining process. The results of research and development work will be demonstrated in industrial context and there is a dissemination and exploitation activity to reach out pote
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'MINIATURIZED LASER SCANNER' (MILS).

assistant: **Innovation**

The object of the MiLs project is the application of microsystems technology to the field of optical laser scanning. The output of the project will be a hands free" micro-scan tool, to be carried on the arm or the finger of the operator, capable of deflecting a laser beam to obtain a scan line and to sense the light diffused by a target, typically a bar code, so producing an electrical output signal. The micro-scan tool will be mainly designed for reading bar codes, but it can be seen as a component useful in many other applications in which a non-contact optical measurement is necessary : examples could be measurement of distance, dimension, surface roughness, presence / absence etc. Current hand held readers on the market, have dimensions and shapes similar to a pistol or an electric razor and, obviously, must be held with one hand by the operator. For ergonomic and economic reasons the market for bar code readers requires systems with smaller dimensions that allow "hands free" operation. Thus, the reader must be small enough to be put, for example, in the shape of a ring. While the electronic part of a bar code reader can be reduced in dimensions by means of the well-known microelectronics technologies, the optomechanical part of the reader has limitations in terms of dimensions. For this reason in the MiLS project the LIGA process will be used to fabricate the optomechanical part. The LIGA process allows the miniaturisation of the optical set-up by fabricating integrated optomechanical parts. They include optical structures, fixing structures for optical elements like laser and photodiodes as well as mirrors or lenses. The architecture of a scan tool typically comprises a laser diode emitting a laser beam, optics to focus the laser beam to the desired distance, a mo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Towards a New Generation of Coated Hobs', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The objective of the project is to lay the technical base for the development of a new generation of HSS coated hobs suitable for high speed and dry cutting. These are the demonstrations of the feasibility of coated hobs, that can be used in dry cutting and coated hobs with a significant performance gain (at least tripling specific chip volume) over current products in lubricated cutting. The future European generation of hob coatings will be conceived for: - work in dry or marginally lubricated cutting, - display of a predictable wear, - cutting of tougher materials with higher specific chip volume, - recoating after resharpening with the same productivity after the different resharpening and recoating cycles. * One of more important industrial objective is the possibility to increase the hobs productivity with an improvement of cutting speed. * We can expect to reach with an innovative HSS coated hob a maximum value of Vt: 250 m/min corresponding a high improvement of chip volume / time, and a subsequent decrease of machining costs of about 30%. * A second industrial goal is to improve the roughness of the workpiece in direction to reduce the number of successive operations during the fabrication of gears, and to improve the quality of final products. This improvement can reduce the total production gear costs of about 5-10%. * An other industrial objective is the reduction (partially or totally) of lubrification (dry or near-dry machining) with a subsequent reduction of machining costs of about 14 -16%. Due to environmental, health, and economic considerations, there is a strong user demand to replace the coolant machining with a lubricant-free machining. The project is subdivided into 3 workpackages: - WP1: (preparation): the first wp is dedicated to prepare the gro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Molecular Robotics for Synthesis and Catalysis' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The aim of this project is to design, synthesize and investigate the operation of synthetic molecular machines capable of performing sophisticated tasks in chemical synthesis. The molecular machines are inspired by biological systems, where substrates are shuttled between different enzymatic sites, undergoing chemical transformations at each step. Control of substrate position allows for reactions to occur in a specific sequence, with the molecular machine dictating the selectivity of each successive chemical reaction. The project both seeks to optimize the structure of the molecular machines for use as a synthetic platform and demonstrate their usefulness for synthesis and catalysis in model reactions. The successful demonstration of this concept would mark the beginning of a fundamentally new approach for the construction of molecules.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Cancer immunosurveillance-stimulatory effects of ACBP/DBI neutralization'.

assistant: **Concept**

Acyl CoA binding protien (ACBP, encoded by diazepam binding inhibitor, DBI) is a novel glucocorticoid-induced tissue hormone that contributes to tissue aging. In still health individuals, the plasma concentrations of ACBP/DBI protein increase before cancer diagnosis. ACBP/DBI mediates immunosuppressive effects, meaning that its neutralization improves cancer immunosurveillance. Therefore, ACBP/DBI might be considered as an immune checkpoint. Thus far, we have demonstrated the immunostimulatory and cancer immunotherapeutic effects of ACBP/DBI inhibition by the inducible knockout of the Dbi gene or by means of a tool antibody recognizing mouse (but not human) ACBP/DBI protein. Here, we propose the validation of an interspecies cross-reactive monoclonal antibody (mAb) recognizing an epitope that is shared among human and mouse ACBP/DBI. We plan to test this new (unpublished) antibody in three experimental settings: (i) the neutralization of human recombinant ACBP/DBI protein, abolishing its capacity to elict chloride fluxes via the GABAA receptor expressed by human cells; (ii) the reversal of the immunosuppressive effects of  human recombinant ACBP/DBI protein or glucocorticoids (which transcriptionally induce ACBP/DBI) on primary human peripheral blood mononuclear cells; and (iii) the improvement of immunosurveillance and the reversal of immunosuppression by glucocorticoids in mouse models of non-small cell lung cancer, fibrosarcoma and breast cancer. Altogether, these results should allow to file a composition-of-matter patent describing a therapeutically useful anti-ACBP/DBI mAb. Moreover, such data will increase the interest of potential investors in a yet-to-be-financed biotech company developing therapeutic anti-ACBP/DBI mAbs for the treatment of cancer and other age
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Identifying Oscillatory Signatures of Predictive Coding in Hierarchical Auditory Networks with MEG' under Horizon 2020.

assistant: **Concept**

Considerable evidence supports the notion that the brain actively predicts incoming sensory events which are compared with internal models. However, the underlying mechanisms remain unclear. The goal of this project is to identify the role of neural oscillations during predictive processing in a hierarchical auditory network using Magnetoencephalography (MEG). I will examine oscillatory activity during the encoding of predictable auditory events and the subsequent detection of unpredictable deviations in a modification of the roving standard paradigm containing nested levels of acoustic regularities. Specifically, I aim to identify the specific frequency channels underlying the signalling of sensory predictions and prediction-errors across the auditory hierarchy. In addition to studying predictive processing during normal brain functioning, the proposed project will examine aberrant auditory predictive processing in schizophrenia, a disorder characterized by profound abnormalities in auditory perception. Accordingly, the outcomes of this project will not only impact on our understanding of the principles of normal brain functioning but may also have implications for future clinical and translational research.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Compliant Actuation Robotic Platform for Flexible Endoscopy' to be submitted under Horizon 2020.

assistant: **Abstract**

Prof Alfred Cuschieri, the overall coordinator of ERC grant Colonic Disease Investigation by Robotic Hydro-colonoscopy (CODIR - grant agreement 268519) has recently submitted the mid-term scientific report on behalf of the two participating Universities (Dundee and Leeds), which highlights several novel IPR (intellectual property rights) issues resulting from the CODIR research, which are pertinent to robotic flexible endoscopy. One of these is based on the ‘active tether robot’ (ATR) idea for the provision of snake like locomotion; i.e., instead of the locomotive power for the active colonoscope being supplied to the back of the robot via a power cable, the design is turned on its head, and replaced by a motile segmented ‘active tether’, which is itself an endoscope, and which can operate in both a gas and aqueous environment. The platform is based on a Mini Compliant Joint (MCJ), with two degree of freedoms (DoFs) using Shape Memory Alloy (SMA) wires as actuators and torsional springs, a synergistic combination which increases the energy efficiency and mechanical bandwidth performance; and at the same time, reduces heat production and stress on the SMA wires. The MJCs actuates by current-induced contraction of SMA wires, two hollow articulating rings with 2 DoFs. As the rings have intersecting axes, the two torsional springs provide roll and pitch. Such a chain of active MCJs provides sinusoidal motor-less locomotion. In essence, CARPE is a generic modular system (capable of translation into any type of flexible endoscope in current clinical use) consisting of independent segments (much like a biomimetic vertebral column), mechanics and electronics. The big advance of CARPE, when used to construct a colonoscope over the current equivalent endoscope, is that once, the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Adaptable multi-pixel gas sensor platform for a wide range of appliance and consumer markets' (AMUSENS), addressing dissemination and exploitation.

assistant: **Impact**

Gas sensors are crucial in the personal and industrial monitoring to analyze personal exposure to air pollutants or to critical gases, to control product quality such as in the food industry, in health care by analyzing gases from human body and using breath analysis combined with wearable sensors for personal stress estimation. These applications require miniaturized low power and low-cost gas sensors with good gas selectivity to be integrated in personal devices, in product packaging or in widely distributed sensor networks.AMUSENS aims at developing a gas sensor platform with flexible selectivity to different gas environments by combining a multi-pixel approach and artificial intelligence to adapt the data analysis to the targeted applications. It is based on metal oxide sensing materials on micro-hotplate platform, which are already available on the market for low power applications, but suffer from a lack of selectivity. Gas-selective multi-pixel sensors based on different metal oxide materials have been demonstrated, but their industrialization is limited to few industrially available materials. By using original additive manufacturing approaches for local liquid-phase and gas-phase depositions, we aim at extending the choice of available materials and demonstrate their sustainability in wafer-scale processing. Artificial intelligence will be used to accelerate the choice of materials, for data fusion to determine specific patterns in the gas analysis and to optimize sensor calibration through calibration transfer models. Three specific applications targeting personal exposure and health care will demonstrate the adaptability of the platform, based on an analysis of the users' requirements. AI interpretation will be facilitated using model-agnostic interpretabilit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Exploiting innate immune evasion strategies of Staphylococcus aureus for the design of novel antibody-based therapeutic agents for the treatment of bacteremia' (COMPSTAPH) targeting Seventh Framework.

assistant: **Abstract**

Staphylococcus aureus is a widely disseminated human pathogen whose virulence is associated with a broad range of severe and potentially fatal health complications. It has been shown to produce a series of immunomodulators that promote virulence by affecting both arms of the host immune response. Complement (C’) represents a key innate immune effector that protects against infection, and S. aureus has evolved several strategies to evade C’ neutralization. C’ proteins are essential for the propagation of host inflammatory reactions to bacterial infection and serve as attractive targets for the dampening of this response by pathogens. Indeed, several S. aureus-secreted proteins have been described to have C’ inhibitory activity. To this date, no systematic research effort has been placed on the development of complement-based antimicrobial therapeutics that might exploit immune evasion mechanisms of S. aureus. The current proposal focuses on dissecting critical interactions of S. aureus immune evasion molecules with key components of the innate immune response (complement and cytokine networks) by means of antibody-targeted studies on virulence and inflammation. Our research aims to: 1. Characterize antibodies from S. aureus-exposed individuals that recognize key microbial evasion targets and can attenuate inflammation in a whole blood model of S. aureus-induced bacteremia. Studies will also focus on dissecting the neutralizing capacity of these antibodies on a broad spectrum of inflammatory mediators triggered by bacterial infection. 2. Develop single-chain antibodies against S. aureus proteins identified in Aim 1 as being targets for pathogen neutralization by phage library approaches. The therapeutic efficacy of these library-generated antibodies will be evaluated in i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Knowledge Graphs at Scale' (KnowGraphs).

assistant: **Innovation**

Knowledge graphs (KGs) are a flexible knowledge representation paradigm intended to allow knowledge to be consumed by humans and machines. Hence, they are regarded as a key enabler for a number of technologies including question answering, personal assistants and artificial intelligence across all sectors including Industry 4.0, personalized medicine, legislation, economics and more. While different implementations of the KG paradigm are now used by several large companies (incl. Microsoft, Google, Facebook, Amazon, Samsung, Ebay and IBM) as a key component of their data products, their use is currently unattainable for the majority of companies and private users. Custom formal representation mechanisms, organisation-specific storage solutions and query languages as well as large dedicated maintenance teams (often 100+ people per graph) are only some of the current challenges faced by organizations aiming to manage KGs at scale. Developing and maintaining a company-specific infrastructure to represent, construct and maintain KGs is only viable for large organisations able to afford the corresponding costs. In addition, a plethora of open questions pertaining to the transfer, applicability and integration of legal rights of knowledge graphs remain completely unsolved. The overall objective of KnowGraphs (summarized in Figure 1.1) is to scale knowledge graphs to be accessible to a wide audience of (1) companies of all sizes and (2) end users across their professional and private life by using a multi-disciplinary and multi-sectorial approach.


**Keywords:** Knowledge Graphs, Semantic Web, Knowledge Representation, Scalability