RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'A neuro-dynamic framework for cognitive robotics: scene representations, behavioural sequences, and learning' (NeuralDynamics) under Seventh Framework.

assistant: **Objectives**

Endowing robots with cognition is a long-standing and difficult objective. Substantial progress in cognitive science and neuroscience has led to the insight that cognition is tightly linked to the sensory and motor surfaces, and that cognition emerges during development from relatively low-level mechanisms when situated in a structured environment.Building on basic functions such as detection and selection, we will develop a set of elements of cognition and techniques for combining such elements, allowing us to scale towards such cognitive capabilities as scene representation and sequence generation. We will implement and evaluate these elements of cognition in scenarios inspired by the development of cognition in early childhood.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Approximation and randomized algorithms in communication networks' under Fifth Framework.

assistant: **Concept**

We are rapidly moving towards an information infrastructure that does not distinguish between computing and communication, but rather provides an integrated set of distributed services to the user. The research community must be prepared to deal with these changes, integrating the disciplines of communications, networking and traditional computer science. On the basis of this belief, our network intendeds to develop a training and research programme which provides fundamental tools in advanced networking technologies (Optical Networks, Radio Networks and Satellite--Based Mobile Systems), and in constructive Computer Science (design and analysis of algorithms). The senior members of this project have differentiated research experience in all above areas and will educate young researchers to fully exploit the power of advanced algorithmic techniques to obtain efficient solutions to the realistic algorithmic problems arising by the efficient use of the above networking technologies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Enhancing gene network inference from single-cell transcriptomics data through biophysical constraints' (2014-2020).

assistant: **Concept**

Regulatory processes within living cells have long been the topic of research interest and the key to understanding various diseases. The decades of studies resulted in a large body of knowledge on molecular interactions and regulatory pathways in the cells of model organisms ranging from microorganisms to mammals. Nevertheless, accurately inferring gene network topology at the scale of a whole cell has remained an intractable task until recently, mostly due to the large amount of single-cell data needed for such inference. In the last few years, single-cell RNA sequencing (scRNA-seq) technology enabled measuring transcriptome of high numbers of individual cells, which allowed observing a much grater share of the multidimensional parameter space of large gene networks and gave rise to multiple inference methods. However, none of the existing methods incorporates all relevant knowledge on biophysical constraints.  This project aims to incorporate prior knowledge on the system; decomposition of measurement, extrinsic and intrinsic noise; and accurate representation of stochastic gene expression and its regulation into a Bayesian inference framework for identifying topology of a gene network and rate constants of its molecular interactions. The performance of the inference algorithm will be tested by evaluating its ability to predict the effects of transcription factor deletion perturbations. Enhancing gene network inference by accounting for the wealth of known biophysical constraints could provide insights into the gene regulatory processes that would enable advancement in developmental and evolutionary biology, biomedicine and bioengineering.


**Keywords:** single-cell RNA sequencing, integrative analysis of heterogeneous data, noise decomposition, network inference, n
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Transcription-induced Plectonemic Supercoiled DNA' (TiPS-DNA).

assistant: **Concept**

In our cells, DNA is extremely highly compacted to fit within the cell’s nucleus. While being compacted, the DNA still needs to remain accessible to various processes such as gene expression during the cell cycle. So how is DNA spatially organized? How does this compacted DNA interact with enzymes? Does compacted DNA superstructure have a biological role? Answering these daunting biological riddles through a targeted physics approach is the central motive of this proposal. I aim to investigate how supercoiled DNA plectonemes, the basic unit of DNA superstructure found in chromosomes, is linked to its biological functions in gene regulation. Throughout the proposed biophysics experiments in this project, I aim to obtain direct experimental proofs that reveal the mechanism behind the transcription-induced DNA supercoiling. I will co-visualize RNA polymerase interacting with supercoiled DNA in real-time and study the relevant dynamics during  complex formation and transcription. To this end I will employ a novel single molecule in-vitro assay, Intercalation-induced Supercoiling of DNA. This assay utilizes intercalating dyes to induce supercoiling as well as to visualize the formation of DNA-plectonemes. The technique is solely based on fluorescence microscopy and allows for tracking DNA plectonemes and labelled enzymes with ease and with high-throughput. This project will provide the first direct evidence on the role of DNA supercoiling – a fundamental yet not-well studied phenomenon in cell biology – in mediating the activity of DNA-binding enzymes as well as on the origins of dynamic DNA supercoiling in the topological domains of the genome. The result of this project will be crucial for the understanding of the physical interactions that couple chromosome organisation t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Advanced coding techniques for mitigating error floors' (ERRORFLOORS), addressing dissemination and exploitation.

assistant: **Impact**

Iterative decoding algorithms for low-density parity-check (LDPC) codes are known to be subject to decoding failures that result in high error floors in the bit error rate performance curves. Recently, researchers became aware that the error floor was a result of a number of properties of the code's graph representation, including cycles, stopping sets, trapping sets, absorbing sets, and pseudo-codewords.This research aims at analyzing the error floor phenomenon for these structures and developing improved code representations as well as decoder architectures to mitigate the error floor. The convolutional counterparts of LDPC codes, namely LDPC convolutional codes will also be examined in this scope. It is proposed to extend the results to the decoding of conventional codes with denser graph representations, where the error floor issue is even more severe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Non-Equilibrium Diffusion in Complex Environments' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Diffusion is at the root of a huge number of microscopic structural and transport processes. During the last century, Einstein and Boltzmann's theories were successful in describing equilibrated systems, but they are not applicable to numerous strongly non-equilibrium conditions in nano-technological and macromolecular-scale biological contexts. Notably, many systems involve energy injection at an interface, either under dissipative shear flows or chemical reactivity. These common non-equilibrium situations are difficult to observe with precision and describe with statistical theory. NoDiCEs purpose is thus to design model experiments placing functional colloidal particles in complex, non-equilibrium environments with quantitative assessment based on delicate and simultaneous observations of the particles advective and diffusive motions, along with their precise spatial organization. Our observations exploit evanescent- wave microscopy to observe fluorescent nanoparticles driven out-of-equilibrium in microfluidic devices, providing 3D nanometric precision at kHz temporal scales. Fluorescence correlation and atomic force spectroscopies complement these measurements, providing DC to MHz bandwidth and similar spatial precision. We will demonstrate how non-trivial interactions of hydrodynamic origin with a boundary reveal novel nanoscale self-organization strategies, and learn how to integrate a hydrodynamic component into the statistical theory. We then enter the recent scientific debate about the extent to which Brownian motion can be impacted by reactive environments with catalysis. Lastly, we combine these elements with particles that present specific surface binding and are driven out of equilibrium by an external flow. The insights provided by our model experiments op
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Silicon Through holes by Accumulative interplaY of 2 Micron short pulsEs'.

assistant: **Innovation**

At a time when digitalization is omnipresent in our daily lives and silicon-based devices remain a key factor, the demand for high-density interconnections and increasingly compact, reliable electronics is essential for the continued advancement of semiconductor technologies. Through-Silicon Vias (TSV), the vertical interconnects that make true 3D integration possible in CMOS chips, MEMS sensors, and AI hardware play a key role. The STAY2ME project lays the foundation for a radical shift in how silicon structures that drive tomorrow’s technologies can be shaped and connected. Our radically innovative laser-based technology enables non-contact, chemicals-free, high-aspect-ratio micro-drilling within silicon, delivering unprecedented precision without detrimental side-effects in the surrounding material. This will be a game-changer for fabricating TSV. At the core of this innovation is a mJ-energy class laser operating at 2 micrometers in the novel GHz-burst regime, where a rapid train of pulses is delivered in ultrashort bursts. This laser combines the right wavelength with the right pulse dynamics, achieving nonlinear absorption and how energy accumulates in silicon-thus avoiding the laser beam distortion and chaotic energy deposition that plague existing methods. It could outperform the precision, speed and sustainability of Deep Reactive Ion Etching, today’s state-of-the-art for TSVs, and transforms what was once a materials limitation into a design revolution. Understanding and controlling how such a laser interacts with silicon is a breakthrough, opening a fundamentally new regime of laser-based silicon processing which offers unprecedented control over the drilling process. One of the unique strengths of this project lies in its interdisciplinary consortium, bringi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'IMPROVING THE YIELD STABILITY OF DURUM WHEAT UNDER MEDITERRANEAN CONDITIONS' (OPTIWHEAT) under Sixth Framework.

assistant: **Objectives**

Water is essential to sustaining human and environmental health but is already at scarcity level in some Eastern and Southern Mediterranean countries. Agriculture is by far the largest user of water resources accounting for around 75% of consumption, but n ever the less water remains a major determinant of crop yield. Under rain-fed conditions, characterised by low and uncertain rainfall, Durum wheat is one of the most widely cultivated crops. This project seeks to use a powerful systems-biology approach com bining genomics, crop physiology and agronomy to generate Durum wheat cultivars that have higher and more stable yields under Mediterranean drought conditions. The central thrust of the project is to both identify existing variation in Durum wheat germpl asm and to generate novel genetic variation for the stability of yield under drought stress (SYDS) in Durum wheat. The project will generate a novel mutant population and use these lines to establish TILLING for the first time in Durum wheat. This popul ation will be used for forward and reverse genetic approaches to identify lines with enhanced SYDS and to understand how the structure and expression of specific genes contribute to the variation of yield trait components under Mediterranean conditions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Advancing Resilience of Historic Areas against Climate-related and other Hazards' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

ARCH will develop a unified disaster risk management framework for assessing and improving the resilience of historic areas to climate change-related and other hazards. This will be achieved by developing tools and methodologies that will be combined into a collaborative disaster risk management platform for local authorities and practitioners, the urban population, and (inter)national expert communities. To support decision-making at appropriate stages of the management cycle, different models, methods, tools, and datasets will be designed and developed. These include: technological means of determining the condition of tangible and intangible cultural objects, as well as large historic areas; information management systems for georeferenced properties of historic areas and hazards; simulation models for what-if analysis, ageing and hazard simulation; an inventory of potential resilience enhancing and reconstruction measures, assessed for their performance; a risk-oriented vulnerability assessment methodology suitable for both policy makers and practitioners; a pathway design to plan the resilience enhancement and reconstruction of historic areas; and an inventory of financing means, categorised according to their applicability in different contexts. The project ensures that results and deliverables are applicable and relevant by applying a co-creation process with local policy makers, practitioners, and community members. This includes the pilot cities Bratislava, Camerino, Hamburg, and Valencia. The results of the co-creation processes with the pilot cities will be disseminated to a broader circle of other European municipalities and practitioners. ARCH includes a European Standardisation organization (DIN) as a partner in order to prepare materials that ensure that
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'The CALIPER project: Linking research and innovation for gender equality'.

assistant: **Objectives**

The CALIPER project aims at driving a structural change process and implementing Gender Equality Plans in 7 Research Performing and 2 Research Funding organizations, involving the highest and middle management levels since the beginning to impact the whole institution. The project goal is to make research organizations more gender equal by increasing the number of female researchers in STEM, improving their careers prospects and integrating a gender dimension in research. CALIPER is featured by a broad geographic focus and an innovative approach based on engaging national and regional innovation ecosystems in the partners’ countries with a quadruple helix approach: the project will trigger and make internal changes and gender equality policies sustainable by orchestrating the core inward auditing/internal assessment and GEPs design with outward actions engaging external stakeholders to activate synergies at all different junctions of the ‘education-research- transfer to market of STEM research results’ chain. CALIPER will adopt an intersectional approach to gender equality issues, paying attention to the ways gender inequalities are linked to and intersected with other discriminations. CALIPER will ensure its successful implementation by adopting a holistic methodology featured by capacity building support to build and sustain internal gender knowledge and expertise, mutual learning among partners, a participatory co-design of GEPs as well as 2 iteration levels for implementing and refining GEPs and a thorough monitoring and evaluation mechanism, leading to durable institutional changes. Thanks to the presence of α pan- European Professional association in the consortium and further dissemination actions such as the Caliper Charter and Code and awareness raising session
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Malopolska Researchers’ Night 2009'.

assistant: **Concept**

Southern Poland will go science mad on 25 September 2009, the third such event in as many years. In Kraków, Tarnów and Nowy Sącz, cities forming part of the “Where the researchers work” route, researchers will come out of the confines of their laboratories and lecture halls, in which they spend their days making discoveries and exploring the frontiers of knowledge, to show their other face. Researchers’ Night will provide a chance to meet and interact with researchers not only in their everyday work environment, but also in unexpected situations and venues. Researchers will, in their turn, have an opportunity to challenge stereotypes by casting themselves in entirely new roles: as theatre actors, film directors and many more. Participants in Researchers’ Night will become acquainted with the cutting edge of scientific discovery. This will be a unique opportunity to get in touch with “true” science by exploring places that are otherwise inaccessible to the public: laboratories and other research facilities. Everybody will be able to approach researchers with questions. The project is based on a formula of hands-on demonstrations, dazzling experiments, entertaining discussions, amusing plays and interesting workshops and is designed to ensure that there will be enough variety for everyone to find something interesting to do. Malopolska Researchers’ Night is becoming a regular fixture on the region’s calendar of events. The previous year’s project attracted as many as 15,000 participants, providing us with experience to build on for future success. Malopolska Researchers’ Night 2009 will take place in Kraków – Poland’s most beautiful city, a centre of science and the seat of the oldest university in Eastern Europe – and in Tarnów and Nowy Sącz, new but rapidly growing rese