RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'In-situ Topological Reduction of Scientific 3D Data', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Modern scientific methods heavily rely on large-scale 3D simulations. However, current data production speeds are much higher than storage speeds (5 orders of magnitude on typical supercomputers). This imbalance constitutes a major bottleneck in the scientific computing pipeline, such that most of the data generated by a simulation is not saved to disk, and thus remains unvisualized, unexplored and unanalyzed. TORI addresses this data bottleneck by introducing the next generation data reduction tools for large-scale scientific 3D data. TORIs angle of attack is based on original and important advances in Topological Data Analysis (TDA), a class of techniques popularized in scientific visualization. TORI addresses data reduction at two levels: (i) at the data level, by deriving an analysis framework for ensembles of topological objects that is inspired by optimal transport, and (ii) at the computation level, by entirely revisiting TDA to adapt it to the context of high-performance in-situ data analysis. To identify informative datasets (i), TORI will introduce efficient methods for distance computations, barycenter evaluations and trajectory analysis. To perform this analysis on-the-fly (ii), TORI will revisit TDA with task parallel algorithms, coarse-to-fine computations and TDA-aware lossy compressors. TORI will be implemented in open-source in the Topology ToolKit, a leading TDA package, and interfaced with standard scientific computing packages (VTK, ParaView). It will be integrated in simulation codes with Catalyst and evaluated on real-life use cases in climatology, geophysics and astrophysics. TORI will have a far reaching impact on all fields of science using large-scale 3D simulations. By bringing together optimal transport and TDA in an innovative coarse-to-fine
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'BOOSTing the industrial application of green carbides by thermal spraying in protective coatings' to be submitted under Horizon 2020.

assistant: **Abstract**

The BoosT project aims to introduce advanced materials as alternatives for the efficient deposition of wear and corrosion resistant coatings by Thermal Spraying in highly demanding applications. The project goal is to substitute the currently critical materials used in Thermal Spraying coating – Co, Ni and WC, CrC- by green elements as Fe, Ti based metals and TiC, SiC carbides. BoosT materials and coatings will be depolyed in several industrial applications with advanatages in terms of cost savings, securing of raw material sources and removing of toxic materials. This will be possible by using the BoosT nanostructured powder produced by Mechanomade® technology of MBN for the deposition of coatings with superior characteristics compared to the current thermal spraying materials (WCCo and NiCr3C2). In the framework of the scope and the expected impact of the call the following objectives have been identified •Optimize the production route of innovative nanostructured cermets powders for thermal spraying with improved wear resistance and corrosion inhibition •Optimize the thermal spraying process by HVOF and extend spraying procedures to other methods as CGS and HVAF •Increase the robustness and repeatability of the industrial processes of powder production plant able to deliver up to 50tons/year of nanostructured powder •Qualification of the pilot production route for the application of the coating on components for pulp and paper , food processing, mechanical industries with massive cost saving up to 60%•Commercial proposition of coatings and materials to early adopters industrial customer The BoosT exploitation and business targets are to:  - replace WCCoCr products occupying the related market segments - acquire by 2022 20 early costumers to sale about 30-40 tons of B
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Structural response of photosynthetic apparatus to stress'.

assistant: **Objectives**

Photosynthesis is one of the most important biological processes on Earth. Photosystem I and Photosystem II are the key protein complexes in the photosynthetic or thylakoid membrane of chloroplasts for converting light energy. They mediate light-driven electron transport through the thylakoid membrane with help of additional light harvesting proteins. Both Photosystem I and II are organized into large supercomplexes with variable numbers of specifically attached membrane-bound light harvesting proteins. Under varying natural conditions plants have to regulate light harvesting to keep maximum efficiency of photosynthetic reactions under light limiting conditions and to prevent the photosynthetic apparatus from photooxidative damage under high light conditions. Acclimation and protective mechanisms involve considerable structural changes at the level of both individual photosynthetic proteins and the entire photosynthetic membrane, which are largely unexplored. Increasing our knowledge of stress induced structural changes of the photosynthetic apparatus is important for overall understanding of regulatory mechanisms of photosynthetic performance. Such information is of great importance to e.g. a booming field of artificial photosynthesis, which tries to mimic photosynthetic reactions at the laboratory conditions. The aim of proposed project is to monitor stress-induced structural changes (different light conditions, elevated temperature) of the plant photosynthetic apparatus at the level of individual supercomplexes of Photosystem I and Photosystem II and their associated antenna complexes using transmission electron microscopy and single particle image analysis. Another challenging aim of the research proposal is a visualization of stress-induced structural changes of (i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Transformation of fruit flies of economic importance with emphasis on tephritids - ceratitis capitata, bactrocera spp' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

The main objectives of the project are:* To develop versatile vectors for transgenesis of Tephritid diptera, based on the transposable elements that have already been used for germ line transformation of other non-Drosophila insects.* To identify dominant genetic markers appropriate for detection and study of the transgenes.* To genetically transform at least one fruit fly species of the Bactrocera dorsalis complex with one or more transposon-based vectors and the appropriate markers.* To assess the genetic stability of the B. dorsalis transgenes under conditions of mass culture in the laboratory.Expected OutcomeThe work carried out in this project should result in the optimization of existing technology and the development of new technologies for germ line transformation of Tephritids of economic importance. It should identify new transposon vectors for stable transgenesis and dominant genetic markers for identification and assessment of the transgenes. The project should lead to the production of several transgenes of B. dorsalis, an agricultural pest of great importance for SE Asia, and the assessment of the stability of these transgenes under mass culture conditions.The activities envisaged are:* Assessment of stability of existing fruitfly transgenes. Transgenic Medfly (C. capitata) strains, each carrying a single, independent chromosomal insertion of a Minos transposon marked with the white dominant eye color gene in a white mutant genetic background will be used. Phenotypic reversion or modification will be followed for about twenty generations in population cages.* Characterization of endogenous transposable elements in two model species, C. capitata and B. tryoni, and in species of the B. dorsalis complex. Using PCR, sequences related to hobo, Minos, and marine
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Isolation of bacteria and extracellular vesicles from body fluids for improved diagnostics' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

This project aims to deliver a microfluidic platform capable of isolating bacteria and Extracellular Vesicles (EVs) at high throughput and high recovery rates from clinical samples, and perform the necessary downstream analysis for the diagnosis of diseases requiring earlier/urgent treatment. Currently, long incubation steps required for identification and susceptibility testing of pathogens make clinicians to prescribe broad-spectrum antibiotic treatments in sepsis cases upon hospital admission, and in nearly half of cases this treatment fails. On a different timescale, the lack of symptoms until late stages of some cancer types such as pancreatic cancer means a high mortality rate. Profiling molecules contained in EVs —most importantly DNA, RNA, proteins and lipids— promises a powerful diagnostic tool as biomarkers for cancer, but current EV isolation methods relying on ultracentrifugation are lengthy and can potentially damage the information enclosed. Microfluidics could provide a high yield, high throughput solution for isolation and enrichment of such particles. However, current approaches do not meet requirements of throughput and/or detection limit, and lack insightful physical understanding. I propose to use novel fluid dynamic and electrokinetic models for particle manipulation in microfluidics, with state-of-the-art fabrication methods to deliver a device capable of rapidly isolating and enriching samples containing (a) bacteria at low concentration (few hundreds per mL) to be integrated in a platform with the potential to identify and perform ASTs in possible bacterial infections in body fluids that avoid culture steps in current gold standards and potentially allow a ten-fold time reduction from sample to answer; (b) EVs to replace current ultracentrifugati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'A new experimental apparatus for a fundamental test of quantum electrodynamics: the measure of the magnetic birefringence of vacuum.' to be submitted under Sixth Framework.

assistant: **Abstract**

This proposal is part of a new research project to measure the anisotropy of vacuum induced by a high magnetic field. This is one of the most important predictions of quantum electrodynamic theory, but has not been observed yet. The effect that will be measured is the ellipticity acquired by a linearly polarized laser beam when passing through a high magnetic field region in vacuum. A high-finesse optical cavity will be used to enhance the optical path of the beam in the magnetic field region. With the present technology an increase of the optical path up to one million times is achievable. The key part of the experimental apparatus is a specially designed 1.5 meter long 10 Tesla pulsed magnet. The ellipticity produced by such an high magnetic field will be measured using the state-of-the-art in high-sensitive ellipsometry.The project will result in an advance in high intense magnetic field technology as well as in the applied optical field of high sensitive ellipsometry. From a scientific point of view, besides the great challenge to measure for the first time the magnetic vacuum birefringence, the implications on cosmology and astroparticle physics are also very important: the experiment test both the energy of the quantum vacuum, whose value influences the universe dynamics, and the existence of new particles which are dark matter candidates.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Update and further development of the european radiobiology archives' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The International Radiobiology Archives is a cooperative venture by European,jointly with Russian, US, and Japanese scientists to collect and safeguard data from long-term radiation studies on animals to make them available for furthe revaluation. The proposed work will complete and extend the present database and publish it on CD Rom with explanations for distribution to scientists and their institutions. It will also develop a Website containing information on such studies. The database will enable scientists to improve with modern methods organspecific dosimetric models for incorporated radionuclides, and to assess risk estimates especially for radionuclides for which no human data are available. In addition, the database will be useful for studies on aging, risks of cancer, andto test theories on synergistic effects.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Modeling the Physics of Nano-Friction'.

assistant: **Innovation**

In the next five years, novel nanoscale friction experiments will provide decisive data on the physics of a century-old, central, yet incompletely understood area of physics. Nano and mesoscopic phenomena without historical precedent in classic friction are emerging in tip based and other sliding and dissipation measurements. Opportunities for the control of friction, based on harnessing and modifying collective phenomena in the substrate are in the works; and fresh spectroscopic insights into the quantum phenomena in solids and surfaces are currently obtained by nanofrictional means. Finally, exciting laser based sliding nanosystems just appeared. All this experimental opulence demands a strong matching theoretical effort:  and just that is the scope of this project. I and my group will model, calculate and simulate the frictional anomalies accompanying structural and ferroelectric phase transitions as an opportunity for friction control; and will pursue the noncontact dissipation anomalies as a local spectroscopic tool of electronic, magnetic and quantum transitions. A strong priority will be the theory and simulation of sliding in trapped colloids and cold ions on laser generated periodic potentials, where nanoscale and mesoscale sliding phenomena promise to be uniquely accessible. The range of approaches will cover phenomenology, model building and testing, molecular dynamics atomistic simulations of sliding, both empirical and ab initio, electronic and magnetic dissipation modeling; and ordinary condensed matter theory, along with non-equilibrium statistical mechanics. To achieve that scope, I will put together students, postdocs, and leading condensed matter theorists operating mostly in SISSA Trieste, but also in ICTP Trieste and elsewhere, assembling a strong te
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'European Expansion of moveUP' (EXPANSE) under Horizon 2020.

assistant: **Objectives**

2020 will be remembered as year zero of tele-medicine. moveUP has developed a mobile health platform that monitors, informs and treats patients via standardised & validated protocols.    Its first product is in orthopaedics, but with the Corona Crisis and the cancellation of all elective procedures, the platform has been extended to other pathologies.  On 18/03, a monitoring protocol of suspected Covid19 patients has been offered to General Practitioners (GP), enabling them to follow-up symptoms of hundreds of patients, and intervene in case of need.  The topic of this program remains orthopaedic joint replacements. But the benefits of the solution and its applicability for infectious or disabling diseases which restricts movement to the GP will be clear to the reader.  Joint replacements are referred to as the surgery of the century, as the number are growing exponentially. But 20-30% of patients remain unsatisfied and quality of care is not measured.  moveUP offers patients a safe, efficient and qualitative therapy to be made from the comfort of their home. It uses medical device certified machine learning models to adapt activity level, exercises, medication and coach patients, under uner supervision of healthcare providers.   The therapy has shown in clinical studies to offer excellent outcomes, lower variability, and objective measure of quality, at a lower cost compared to standard of care. More than 1200 patients have been treated and it is the first digital therapy fully reimbursed by the national health insurance in Belgium.   moveUP and has taken first steps to expand across Europe. But the fragmentation of the European Healthcare markets makes it more difficult for a start-up to scale and raise funding.  The purpose of this application is to enable moveUP to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Developing advanced Engine Multi-disciplinary Optimization Simulations (DEMOS)', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The “Innovative Aircraft Architecture” technology stream of the Clean Sky 2 Airframe ITD focuses on advanced power-plant solutions (such as CROR and UHBR) that are able to deliver a significant gain in aircraft performance. Project DEMOS will develop advanced predictive modelling and simulation capabilities for engine design space exploration and performance optimization of such novel propulsion systems. The overall and detailed objectives of Project DEMOS may be summed up as follows:• Assess,  adapt and further develop a set of  reliable and robust models to simulate/optimise performance of UHBR propulsion system architectures• Identify, build and integrate simulation models of specific (novel) components which may be considered as enablers of the technology • Demonstrate and assess the effect and influence of these components on the propulsion system performance  in terms of overall performance, increase in mass, effect on lifing characteristics of the propulsion system and on the operating/ maintenance cost• Develop a modular approach to enable integration and further development of main modules/models for preliminary design process • Facilitate complex integration requirements• Improve process efficiency through the development of advanced solvers and adequate numerical methods to address complex system simulations • Development of advanced simulation techniques to improve the monitoring of communication between integrated models, robustness and convergence•  Enable complex propulsion system performance optimisation with constraint handling capability• Develop a suite of advanced solvers to enable extended transient capabilities and simulation of complex systems transients and controlThe project will build on the established multi-disciplinary concept design tools a