RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Bayesian Networks and Non-Rational Expectations' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

This project will develop a new framework for modeling economic agents having ""boundedly rational expectations"" (BRE). It is based on the concept of Bayesian networks (more generally, graphical models), borrowed from statistics and AI. In the framework's basic version, an agent is characterized by a directed acyclic graph (DAG) over the set of all relevant random variables. The DAG is the agent's ""type"" – it represents how he systematically distorts any objective probability distribution into a subjective belief. Technically, the distortion takes the form of the standard Bayesian-network factorization formula given by the agent's DAG. The agent's choice is modeled as a ""personal equilibrium"", because his subjective belief regarding the implications of his actions can vary with his own long-run behavior. The DAG representation unifies and simplifies existing models of BRE, subsuming them as special cases corresponding to distinct graphical representations. It captures hitherto-unmodeled fallacies such as reverse causation. The framework facilitates behavioral characterizations of general classes of models of BRE and expands their applicability. I will demonstrate this with applications to monetary policy, behavioral I.O., asset pricing, etc. I will extend the basic formalism to multi-agent environments, addressing issues beyond the reach of current models of BRE (e.g., formalizing the notion of ""high-order"" limited understanding of statistical regularities). Finally, I will seek a learning foundation for the graphical representation of BRE, in the sense that it will capture how the agent extrapolates his belief from a dataset (drawn from the objective distribution) containing ""missing values"", via some intuitive ""imputation method"". This part, too, borrows id
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Chromatin remodelling and transcription activation by the pho4 transcription factor 'in vitro' and 'in vivo'' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Chromatin remodeling and transcription activation by the Pho4 transcription factor in vitro and in vivo Chromatin plays an essential regulatory role in transcription regulation. However, many of the molecular mechanisms underlying activation domain-mediated chromatin reorganisation remain unknown. Perhaps the best characterised example of an activator-induced chromatin transition is found in the activation of the yeast acid phosphatase gene PHO5 by the transcription factor Pho4. As a consequence of Pho4 binding the PH05 UAS in cooperation with the Pho2 homeodomain protein, four positioned nucleosomes undergo a transition resulting in the entire promoter nd UAS becoming nuclease sensitive. Importantly. the Pho4 activation domain is essential for the Chromatin transition to occur. How the Pho4 activation domain mediates the cromatin transition is not known. By isolating minichromosomes from yeast we have recently been able to demonstrate A ATP and Pho4 dependent chromatin remodelling across the PH05 promoter in vitro The aims of this proposal are: I . To characterise further the ability of Pho4 to remodel chromatin in vitro 2. To define the targets of the Pho4 activation domain vitro and in vivo 3. To determine whether the requirements for transcription activation by Pho4 are the same on different Pho4-regulated promoters.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Pheromone-based sensor system for detecting estrus in dairy cows' (BOVINOSE) under Seventh Framework.

assistant: **Objectives**

In order to control the calving interval, and therefore to optimise milk production and maximise offspring in dairy cattle, artificial insemination (AI) is widely used. Currently, the conception rate of AI varies from 30% to 70%, the most critical aspect of successful conception being the timing of the insemination. Highest conception rates are achieved when the insemination is done 8 to 12 hours after the start of estrus (also known as “standing heat”). The right timing of AI, therefore, is related to detection of estrus in a cow.  The BOVINOSE project aims to develop an “electronic nose” to detect estrus in a dairy cow, and thus to determine the optimal timing of artificial insemination. The physical principle is based on detection of sex pheromones that are exclusively secreted by the cow during estrus. These pheromones are the natural olfactory signal for the bull that the cow is in heat. Simply put, in essence, the device to be developed will mimic the bull’s nose. To this end the info-chemicals that make up the sex pheromones in cows will be investigated, a set of sensors for detection of these sex pheromones (or mix thereof) will be researched, and a functional prototype, consisting of a probe, an array of sensors and dedicated, integrated software for control and user-interaction will be developed and tested in field trials. The impact of the project is high, tapping the dairy farming market, which consists of some 1,700,000 farmers in the EU-27, producing about 135 Billion Kg milk annually. Preliminary investigations show that a selling price of € 1,800 would be economically attractive to the entire SME supply chain, providing an overall estimated profit of 10%-25% (depending on batch size). A sales price of € 1,800 would imply an attractive 15 months payout ti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Biological optimisation and development of processing methods for turbot farming (TURPRO)' under Sixth Framework.

assistant: **Concept**

A sustainable production of turbot will be dependent on a year-round supply of juveniles reared in intensive land-based systems at high densities. To effectively exploit such systems it is necessary to obtain detailed knowledge on the impact of key rearing factors (temperature, photoperiod and water quality) on growth performance, food conversion efficiency, age at first maturity and fish welfare. The current proposal will, through a series of small- and large-scale experiments, provide the turbot aquaculture industry with a strategy that will significantly improve growth, reduce maturation and elucidate the impact of critical water quality parameters. It is foreseen that this will reduce production cost per kg market sized fish. In addition the current proposal will investigate new processing methods especially designed for turbot, where the aim is to improve fish yield and flesh quality. The project will investigate and develop: Optimal temperatures for growth throughout the ongrowing phase. -Production advantages of step-wise temperature regulation as compared to a constant temperature regime. Potential benefits on growth from using extended photoperiods. -Potential effects of environmental manipulations in the early juvenile phase on subsequent growth and maturation in the commercial ongrowing phase. -Water quality requirements of juvenile turbot reared at high densities. Improved processing methods aiming at improved production yield and flesh quality. This project is submitted under the thematic programme ""Food Quality and Safety"", area 5.4.6: Safer and environmentally friendly production methods and technologies and healthier foodstuffs. A priority object is to develop lower input farming systems (aquaculture) for delivering safer, healthier and varied foodstuf
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Nanoscale mineral-microbial interactions, associations, and biosignatures in gypsum stromatolites' under Horizon 2020.

assistant: **Concept**

Gypsum-based stromatolites (GS) make excellent paradigms for the investigation of fine-scale mineral-microbial interactions and for the detection of life remnants on gypsiferous deposits of Earth and Mars. Yet, they have been largely overlooked compared to the carbonate microbialites. To date we do not know: i) what is their exact mineralogy, ii) which microbial communities are associated to these structures, iii) what is the exact role of microbes and related bioproducts (e.g., exopolymeric substances) in mineral precipitation and stromatolite construction, and iv) which biosignatures may be preserved in GS. NanoBioS aims to address this knowledge gap by employing an interdisciplinary approach to study newly discovered gypsum-based stromatolites from Lake Bakili (Danakil Depression, Ethiopia) from a combined microbiology and mineralogy perspective. The Danakil Depression and the difficult-to-access and so-far unexplored Lake Bakili constitute a unique, natural laboratory for the study of both living and fossil gypsum microbialites, and a terrestrial Martian analogue-site. Besides the possibility to discover novel microbial lineages/metabolisms, we will attempt to identify characteristic associations of microbial groups with mineral assemblages and look for biosignatures. The overarching goal of NanoBioS is to gain a deeper understanding of the microbial influence on Ca-sulfate precipitation, as well as, to develop insights for distinguishing fossil life remnants from inorganic biomorphs on Earth and Martian chemical sediments.The host and secondment host laboratories that have advanced the subject of geomicrobiology of microbialites, will offer me intensive training in cutting-edge molecular biology and mineralogic tools, complementary to my so far geochemical expertis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Current State of Standardisation and Future Standardisation Needs for Intermodal Loading Units' to be submitted under Fourth Framework.

assistant: **Abstract**

The standardisation of intermodal transport units within standardisation committees has arrived at a critical state. Major decisions have to be taken that will greatly influence the technique and efficiency of intermodal transport in the future, adapted to the market demand.Future standardisation trends and decisions will influence vehicle design and transfer equipment lay-out, as well as the parameters of European infrastructure design, European vehicle legislation and the efficiency of the European transport system, i.e. its ability to serve the principles laid out in the EC Communication on Intermodality and intermodal freight transport in the EU" (COM (97) 243) and contribute to the overall goal of sustainable mobility.The research study will report on the current state of this debate and its historical, technical and economical sources. It will outline the current trends in the standardisation debate and highlight the conflicts that currently are observed and certainly will continue in the future. It will encompass the opinions and expertise of various actors in the field covering all market segments. Finally it will give first recommendations- on the direction that European standardisation of intermodal loading unit must take,- on the possibilities and needs for European transport policy and research to promote this standardisation process,- on the capacity of European transport policy to incorporate the current standardisation proposals and to react to the trends in technology, economics and standardisation of intermodal transport to further promote the competitiveness of the European industry. %"
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Exploiting Laser-driven Plasma Chemistry for Ultra-high Repetition Rate Nonlinear Optics' (EXPLORE).

assistant: **Concept**

Nonlinear optical methods play a crucial role in science and technology and enables scientists across the globe to manipulate light at will and access the entire electromagnetic spectrum, from X-rays to Terahertz (THz) waves via frequency conversion. Accessing material nonlinearities requires high input light intensity, thus novel laser sources are instrumental in advancing nonlinear optics (NLO). The first revolution in NLO was enabled by wide access to femtosecond (fs-) laser sources, that ensured sufficiently high peak powers from table-top systems to access most material nonlinearities. However, these high-peak powers are usually generated at low repetition rates below 1kHz, due to laser source limitations in average power. In this case, the material nonlinearity recovers by the time the next pulse in the train arrives and every pulse sees the “same” material. EXPLORE proposes that the second revolution will be the use of high-repetition rate pulses to collectively tailor the nonlinear properties of the medium and allow for the same interactions at greatly reduced energy, thus opening the door to highly NLO at very high repetition rates without prohibitively increasing complexity, with wide implications across disciplines making use of secondary sources of radiation and nonlinear optical methods.  EXPLORE aims to demonstrate this breakthrough idea by using advanced high-power and high-repetition rate laser technology to significantly enhance the nonlinear response of atmospheric plasmas by driving it at ultra-high repetition rates >10 MHz. In these conditions the air plasma chemical composition does not recover from pulse to pulse and a rich chemical mixture can be tailored to enhance the nonlinear properties such that much lower peak power is required for the nonli
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Spin-Transport in inhomogeneous Ferromagnets' in the context of a Seventh Framework call.

assistant: **Objectives**

It is the aim of this research project to carry out systematic studies of spin-dependent transport in heavy rare earth (RE) metals based multilayered nanostructures. These nanoscale heterostructures made of layered rare earth metals would combine in variety of ways species bearing different magnetic character, such as ferromagnetic and antiferromagnetic order, as well as magnetic layers with non magnetic spacers. There exists a substantial gap in the literature regarding magnetoresistance (MR) studies on rare earth nanostructures, which would be of general interest for basic knowledge to fill in. This way, of particular interest will be to perform MR experiments for current perpendicular to plane configuration in vertically nanostructured RE-based systems, where the magnetic RE slabs show helical antiferromagnetic (AFM) order. For these structures, there exist recent investigations that clearly point to the breaking of the chiral symmetry at the interfaces. This chiral asymmetry in helical AFM is likely to lead to much striking effects in the magneto-transport phenomenology of such so far unexplored nanostructures that we now coin as the so-called anisotropic chiral magnetoresistance in analogy to the already proposed electrical magnetochiral anisotropy in chiral conductors. A second topic that will very much focus our attention is the study of magneto transport in multilayered nanostructures of rare earth metals that would combine ferromagnetic, helical AFM and non-magnetic layers. These studies will look to test recent theoretical predictions that forecast a significant enhancement for the overall performance of such nanostructures, which includes nanostructured slabs with helical magnetic order that bear a spin spiral density wave, for current-driven spin-torque tran
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'High Performance Industrial Protein Matrices through Bioprocessing' (HIPERMAX), addressing dissemination and exploitation.

assistant: **Impact**

Novel enzymatic technologies will be developed for production of high performance, economically viable protein matrices with tailored properties leading to enhanced surface/bulk characteristics. These novel materials will be exploited in textile, leather, materials & medical industry. The choice of matrices is focused on materials Nature has already engineered. Scientifically the objective is to discover novel enzymes capable of modifying/grafting functional groups onto protein matrices, to generate knowledge on enzymatic reaction mechanisms in molecular level using model substrates and to apply this knowledge to real substrates i.e. materials like wool, silk, leather, feather to produce novel tailored materials:-define accessibility and reactivity of target groups in heterogeneous protein matrices-develop screening methods and screen for novel enzymes catalysing modification of protein matrices-produce novel enzymes in pilot scale-exploit novel enzymes in order to develop tailored materials e.g. grafting antimicrobials, hydrophobic agents; cross linking, restructuring, reinforcing to design materials with new properties; producing added-value products from waste material. Proposed STRP integrates complementary know-how from 4 EU and 2 Associated countries. Combination of different expertise of microbiology, biochemistry, enzymologist, fibber research, material science and industry into an interdisciplinary project will create efficient synergy. STRP corresponds to NMP-3.4.2.2-2 generating fundamental knowledge, developing generic technologies, fostering strong position of EU industry in area of smart coatings and thin films functionality by implementing enzyme-catalysed processes & to NMP-3.4.2.3-1 defining accessibility of specific target groups for enzyme-catalysed f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'InCa - Cardio Watch for Continuous Intra-Cardiac Blood Pressure Sensing'.

assistant: **Concept**

Congestive Heart failure (CHF) affects more than 15 million European citizens and 1 in 5 people are at risk of developing CHF in their lifetime. It is the leading cause of hospitalizations in patients over 65 years of age, about 1 in 3 patients admitted to hospital will die within one year. CHF accounts for 1-2% (30 Billion €) of healthcare spending in Europe each year.  The growth in the numbers of patients developing CHF is driven by the increasing age profile of the EU population and by the growing number of people developing obesity.Early death and rehospitalization can be reduced dramatically, when the progress of the heart disease is monitored continuously with a wireless pressure sensor, permanently implanted in the patient’s left heart ventricle or left atrium. The implant can provide physicians with detailed real-time information about the patient’s vital functions (intra-cardiac pressure, cardiac output and heart rate) around the clock. Based on those readings, the physician can proactively direct the patient to tweak the medication for stabilizing intra-cardiac pressure and provide early personalized treatments to avoid a crisis that would otherwise lead to hospitalization or even death. No mobile system is available, which allows to continuously and wirelessly monitor the patient’s vital functions during normal daily activities, e.g. (house-)work, sports or outdoor use or during sleep time.With the strong backgrounds in medicine, medical technology, nano- and micro fabrication as well as engineering and business background of the consortium the first, ultra-small cardiac pressure sensor implant for mobile, continuous 24-7-readout is investigated to be marketed beginning in phase III. One key for success is the incorporation of novel and proven nano-granular