RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Action for the Dissemination and Adoption of the MARTE and related Standards for component based middleware' under Seventh Framework.

assistant: **Concept**

The standardisation of the UML profile for Modeling and Analysis of Real-Time and embedded Systems" (MARTE) in June 2007, has been a great success following a European initiative pushed by CEA LIST, THALES, Cantabria U. and supported at international level by big enterprises like Alcatel-Lucent, IBM, Lockheed Martin, tool vendors like ARTISAN, MathWorks, Mentor Graphics and academics as Carleton U., INRIA and SEI / Carnegie Mellon U.<br/>The challenge now is to disseminate, promote its adoption through the European industry and trigger enhancements reflecting the practitioners' needs. This is essential for Europe due to its very strong economic activity in development of embedded, real time and distributed systems. The risk is that this standard being adopted now internationally would be more quickly adopted by US or Indian actors than by European, while the fundamental effort has been performed and strongly pushed mainly by the European initiators.<br/>The objective of the ADAMS project is to organize and support the dissemination and feedback activity around MARTE in Europe, focusing on transportation domains (automotive and avionics).<br/>A key point for its adoption is to demonstrate and convince about its conformance, usability and efficiency to deal with current middleware technologies used by the embedded system industry, and adapt it as necessary to related standards of the automotive and avionics domain (strongly structured, respectively, on AUTOSAR and the IMA/ARINC and SAE-AADL).<br/>ADAMS wants to exploit the "momentum" created among European industrial partners, tool vendors, and the real-time research communities around MARTE. It targets the necessary dissemination and training activities as well as the efforts to promote the adoption of MARTE and related
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Compact High Brilliance Single Frequency Terahertz Source'.

assistant: **Innovation**

We propose an integrated high power single frequency terahertz source. This source will include a double wavelength solid-state infrared laser developed specifically for this application with two different intra-cavity laser materials that will emit at close but distinct infrared wavelengths.The combination of the two emitted wavelengths in organic materials OH1 (2-(3-(4-hydroxystyryl)-5,5-dimethylcyclohex-2-enylidene)malononitrile) and DSTMS (4-N,N-dimethylamino-4'-N'-methyl-stilbazolium 2,4,6-trimethylbenzenesulfonate) will produce high power monochromatic THz radiation at a frequency determined by the difference of the infrared wavelengths. We propose the realization of two different terahertz sources one operating at 4.27 THz, the other one at 9.31 THz. For these two THz sources we will develop two different double-frequency lasers TWIN-1 and TWIN-2. The first one will be based on Nd:YAG and Nd:YLF as laser hosts, with emission wavelengths at 1.33 µm and 1.31 µm. TWIN-2 uses Nd:YAG and Yb:YAG as laser hosts, with emission wavelengths at 1.03 µm and 1.06 µm. Both TWIN-1 and TWIN-2 will operate within a common and compact laser cavity.The high THz power which can be generated in a compact device is due to the very high nonlinear optical susceptibility, the low THz absorption and the relatively high optical damage threshold and phase matchability of the OH1 and DSTMS crystals. A fully integrated, compact, all solid state system operating at room temperature will result from this research. This high power single terahertz frequency source will be used to investigate non-destructively high molecular weight polyethylene materials for biomedical applications.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Spatial and temporal regulation of the fungus-host interaction during life-threatening fungal infections', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The major fungal pathogen, Candida albicans, has a significant impact upon the health of the European population. Candida frequently causes oral and vaginal thrush, and life-threatening infections in intensive care patients. These infections drain European finances through lost working days and extended patient hospitalization. A major goal is to understand how this fungus interacts with its human host and how these interactions contribute to pathogenesis. This will enhance efforts to develop accurate diagnostics for systemic candidiasis. Candida pathogenomics has advanced rapidly in the last decade. Nevertheless, our understanding of fungus-host interactions remains rudimentary. Therefore, our Grand Challenge is to exploit advanced new tools to accurately capture the spatial and temporal regulation of fungal molecular responses in lesions during disease progression. My laboratory is uniquely placed to address this challenge using a powerful combination of new, state-of-the-art technologies. Laser capture microscopy, ultrasensitive microarray technologies and 2D-MALDI-ToF mass spectrometry will be used to define the C. albicans transcriptome and infectome, both spatially and temporally, across fungal lesions during disease progression. C. albicans infections will be imaged with a novel ultrasensitive reporter to confirm the dynamic regulation of specific cellular processes during disease progression. Then precise molecular tools will be used to establish the relative contributions of these processes to the infection process, and to explore candidate diagnostic targets identified during this programme. This will dramatically advance our understanding of fungus-host interactions and will identify potentially novel biomarkers of deep-seated systemic candidiasis.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Wildlife vaccination against rabies in difficult and emergency situation and its potential impact on the environment', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Sylvatic rabies has been partly eliminated from large parts of several Member States by oral immunisation of foxes, but a dramatic increase in fox population densities renders a complete eradication of the disease more difficult. More likely an irrepressible come back of the disease will be seen in the future in areas freed from the disease just a few years ago. This threat comes from remnant focii centralized in rabies-free areas and from non member-states where rabies remains present or on the increase. Selvatic rabies is an economic problem. It has a welfare impact, and constitutes a hindrance to free movement within the E.U. The main organisations in charge of the control of rabies in 5 European countries and one laboratory of animal ecology are proposing the development of testing appropriate countermeasurements instead of the currently used and often non efficient classical oral vaccination of foxes. Information on the possible negative impact of rabies elimination must also be obtained which includes a significant increase of fox population. While several European teams are now organising heavy field trials aimed at vaccinating fox cubs, nothing is known about the immunological competency of fox cubs. Other new measures in practice consist in increasing the density of baits deposited or vaccinating the same areas two times within a short delay. These measures multiply the cost of rabies control. This (suggested) project includes three trials on fox cubs including vaccination of pregnant vixen, and testing on fox cubs subsequently vaccinated or not. Also one must determine the stability of vaccines in use. In fact huge amounts of vaccines are made of viruses very temperature-sensitive. In most European countries, no titre control is done after vaccine distribution
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Ultracold mercury for a measurement of the EDM' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The Standard Model of particle physics (SM), while largely successful, fails to accurately describe the state of the Universe, e.g. with respect to the evident matter/antimatter asymmetry. Various theories seek to conciliate the SM with observations by extending it, and most of these extensions introduce a massive violation of the combined charge invariance and parity (CP) symmetry. The CP violation would reflect in a sizeable permanent electric dipole moment (EDM) of fundamental particles, large enough to be detected by realistic future experiments.A few pioneering experiments already set out to measure the EDM of neutrons, electrons, or atoms. The most stringent upper limit to any EDM is currently obtained by an experiment based on room-temperature gases of mercury. I propose to take this approach to the quantum world by employing ultracold or even quantum-degenerate mercury samples.To this end, we will construct a dedicated quantum gas experiment. We will develop advanced cooling methods, obtain the world’s first Bose-Einstein condensate and degenerate Fermi gas of mercury, and introduce vacuum ultraviolet (VUV) lasers to the field. These ground-breaking innovations will increase the coherence time of the sample, enable a higher detection efficiency, and exploit coherent effects, thereby increasing the sensitivity tremendously. Our measurements of the Hg-199 atomic EDM will complement cold-molecule measurements of the electron's EDM.Technologies developed here can readily be utilized to improve the performance of Hg lattice clocks and will inspire quantum simulations of unique many-body systems.The principal investigator of this project is highly respected for his pioneering work on degenerate quantum gases of strontium. His current work on a nuclear optical clock in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'MicroRNAs as therapeutic targets for ARVC.'.

assistant: **Objectives**

ARVC is a hereditary disease mainly characterised by the progressive substitution of the myocardium with fatty or fibro-fatty tissue involving predominantly the right ventricle. Clinically, ARVC shows wide variation between individuals. Together with modifier genes, common sequence variants, and environmental as well as endogenous factors, epigenetic modifiers such as miRNAs are hypothesized to be potential targets for disadvantageous environmental stimuli and may lead to the onset of complex and heterogeneous diseases such as ARVC. The main research objective of this EF is to assess and validate the relevance of disease mechanisms underlying the development of ARVC and to identify novel RNA-based targets in mouse models and ARVC patients. The EF programme comprises two tightly linked components – research and complementary training - that will be complemented with secondments in two (non-) academic organisations active in the field of molecular cardiology. The host organisations are strongly committed to enhancing the creative and innovative potential of the ER who wishes to diversify her individual competence in terms of skill acquisition to become a successful European scientist.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Quantum communications with photons and atoms' (QUANTCOM), addressing dissemination and exploitation.

assistant: **Impact**

The field of Quantum Information has blossomed over the past few years, driven by the prospects to exploit capabilities from the quantum realm to accomplish computation or communication tasks that are difficult or impossible with traditional methods of in formation processing. This still young research area has swept physicists from a great variety of disciplines and is now at the interface between physics, information theory, computer science and engineering. The recent striking demonstrations of quantum key distribution protocols or quantum teleportation has raised huge interest, confirming the great potential of this field and the dramatic impact that quantum processes can have on information technology. The overall objective of this project is thus concerned with this innovative area of quantum communications, with a particular emphasis on the light-atoms interface required to achieve such purposes.In 2001, a novel approach for long-distance quantum communication was proposed by Duan, Lukin, Cirac and Zoller (DLCZ). This scalable scheme employs atomic ensembles, which can be addressed by laser pulses and single photon detection with not necessary very high efficiency. In the DLCZ protocol, quantum states can be transferred between atoms and photons and stored in atoms for a long time. The abroad phase of the project is mainly concerned by the experimental realization of the DLCZ protocol. During the return phase, the experience gained will be applied in a closely related purpose but in a rather different app roach.The multidisciplinary aspects of quantum information make this a very exciting area to work in, and they provide an excellent framework for the training of an independent research scientist. In addition to complementary competencies such as research manage
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Medieval landscapes in the Horn of Africa. State, territory and materiality of the Adal Sultanate (15th-16th centuries AD).', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

This proposal will study the territory and the material remains of the Sultanate of Adal, a state which during the 15th-16th centuries controlled much of what it’s now Somalia and southern Ethiopia, organizing the international trade routes in the region and challenging the power of the Christian kingdom of Abyssinia until its collapse by the end of the 16th century. The history of this state is partially known through written sources, but has never been investigated from an archaeological point of view. This project will analyse how the different communities living in the Adal sultanate (nomads, urban dwellers, international traders) built a shared, cultural landscape and integrated it in one of the most successful trade networks in the world. Following a Landscape Archaeology perspective and using an innovative combination of methodologies and research strategies supported by GIS analytic tools, the project will present alternative interpretations to some of the most important topics in African archaeology: processes of urbanization, relationships between nomads and urban dwellers and continental and international trade routes. Beyond the study of a single archaeological case, the project will address key questions related to current challenges in the region and many other places throughout the world: episodes of religious conversion, environmental stress and climatic change; and will support the existing initiatives to preserve the archaeological and cultural heritage in the Horn of Africa.


**Keywords:** African Archaeology, Horn of Africa History, Archaeology of territory, GIS, Trade networks, Somalia, Medieval archaeology, Archaeology of State
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Resurrecting the Carboxyl Polyether Ionophores' (RECYPION), addressing dissemination and exploitation.

assistant: **Impact**

The carboxyl polyether ionophores (CPIs) is a class of >150 complex natural products. Belonging to the most complicated of Nature's secondary metabolites, they are darlings within total chemical synthesis, however, the biological role of these agents is obscure. Due to their canonical function of equilibrating ion-gradients across biological membranes, CPIs are thought to be unspecific and largely uninteresting. Here, I will advocate and demonstrate the opposite position: that not only are these compounds extremely interesting with respect to their complex effects on cells, they also harbor a unique anti-microbial activity that should be a strong priority as we stagger towards a post-antibiotic era.    With RECYPION my team and I will draw these compounds back into the spotlight. We will ask the following fundamental questions: 1. Can we develop a synthesis-paradigm that will significantly expand the CPI-chemical space to fully explore their anti-microbial activities? 2. What are the molecular determinants that control the antibiotic-potential of the CPIs, and how do these relate to the mechanism of ion-transport? 3. Can we uncover the cellular activities of CPIs – perhaps even “dark” activities that do not involve ion-transport?        We will pioneer a CPI-synthesis-approach based on the ability to recycle complex components from highly abundant CPI-family members. To do so, we will develop novel chemical transformations to deconstruct these molecules which may find broader use in a world that is increasingly focused on how to preserve resources. We will provide the first real experimental characterization of the molecular mechanism by which CPIs mediate ion transport by using ultrafast surface-sensitive spectroscopy on membrane-resident CPIs along with unprecedented
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Sea straits and biogeography: the role of the Strait of Gibraltar in shaping European-African heathland plant biodiversity' in the context of a Horizon Europe call.

assistant: **Objectives**

The Strait of Gibraltar is a unique hotspot of plant biodiversity within the Mediterranean basin, considered as both a glacial refugium and a relatively permeable biogeographical barrier for plant biodiversity, due to its geological, edaphic and climatic singularities. At both sides of this strait, two heathland habitats of high conservation value and shared edaphic features (acid, infertile and sandy soils) deserve attention: Mediterranean dry heat (herriza) and temperate Atlantic wet heath, whose floras present a peculiar population genetic structure pointing to eco-evolutionary processes such as successful colonisations across the Strait of Gibraltar and isolation by ecogeographic barriers as main drivers in shaping heathland plant biodiversity. Nevertheless, the knowledge about this is still limited. In the present project, a multidisciplinary approach integrating genomics, phylogeography, phylogenomics, demographic inference and community ecology is proposed to contribute to a proper understanding of the role of the Strait of Gibraltar as biogeographical bridge/barrier for both heathland habitats, although particularly relevant for the forgotten but threatened wet heath flora. Likewise, the proposed project will enable to detect key biodiversity areas (probable glacial refugia) and the potential response of heathland plant biodiversity to climate change, essential information for its effective management and conservation.


**Keywords:** phylogeography, evolutionary history, Mediterranean plants, Strait of Gibraltar, climate change