RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Hydrogen PEM fuel cell stack for marine applications' (H2MARINE) under Horizon Europe.

assistant: **Objectives**

The overarching objective of the H2MARINE project is to design, build, test and validate two (2) PEM stacks generating 250 - 300 kW electric power designed for marine applications. The H2MARINE project takes a top-down approach, building on a proof of concept of two PEM stacks that are developed in the EU and Switzerland. The H2MARINE project will: Identify the requirements for the tests and conditions as well as load curves that the FC stacks will have to be tested against with the integrated knowledge of a major ship building industry (ThyssenKrupp Marine Systems) and ship owners (Cleos) representing Gaslog, Drylog Ltd. And Olympic Shipping (totaling more than 100 large ships). - Both PowerCell and EHGroup stack manufactures will benefit from a great consortium surrounding their development, testing and upscaling with unique testing facilities (Beyond Gravity, ZSW, Greenerity, University of Freiburg), industrial partners like DANA, upscaling capacities of stacks by CERTH, EPFL and novel diagnostics development by VTT. This will allow them to enhance the state of the art (SoA) of PEMFC stacks, advance and scale up the system to reach ambitious targets set in the call which will be disseminated by CLUBE member of numerous FCH projects. - Test the proposed solutions in relevant environment/ecosystem, which are designed to fully represent the actual implementation conditions. - Design the stack modules in an optimum manner for up-scaling up to 10MW power train systems. - Test several diagnostics for the stack and overall system integrity as well as for the health status prognosis of critical components.- Assess the technology and economic feasibility of the solution, in order to know its valuable end-use, which will allow the partners to research the potential market/s an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Anaero-control: A new strategy to optimize fermentation performance by means of on-line measurement of compounds by FTIR/ATR-sensors' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

The objective of this project is to demonstrate economical and practical advantages of automated fermentation process control by on-line monitoring of substrates, metabolises and end-products by using on-line FTIR-ATR technology combined with IR/TCD gas sensors. Anaerobic fermentation will serve as an example and it will be shown, that the yield of methane, which is the valuable product in this fermentation, can be optimised We choose this type of fermentation as an application, because it is a type of worst-case scenario due to a very complex sample matrix, a high amount of cells and suspended solids and also difficult analyses. The experiences gained in this process can be transferred to other, completely different industrial fermentation processes like lactic acid fermentation.  By focusing activities of several competitive European SME s and the corresponding biotechnological research, the advantageous and reliable application of fermentation control by on-line FTIR/ATR sensors will be comparably demonstrated by means of 4 company-specific and commercially relevant anaerobic fermentation processes. In the proposed scale the execution of the demonstration project will be representing reality.  Proving the technical viability of the FTIR/ATR sensor technology for on-line measurement and fermentation control will show its advantages with respect to current analytical methods which are state of the art. Special attention will be put on the economic advantages of a higher yield of products at fermentation processes.  Other demonstration goals which need to be achieved are: - fabrication of a prototype of combined FTIR/ATR on-line sensors and fermentation control software - update of MR-compound library for identification of important metabolises - adaptation of file-tran
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'MIcro and NAno TECHnologies and markets' to be submitted under Fifth Framework.

assistant: **Abstract**

Micro and nano (precision) technologies are evolving from a challenging research subject into industrial products in a variety of applications, with markets growing at least at 20% per year. Minatech project will update technologies and markets world-wide past surveys, compare them with SME needs (collected through audits) in 8 EU countries and disseminate all these information to SMEs in the application areas of automotive, information technologies and telecommunications, health/biomedical instrumentation, all high tech and quick growing areas, with already extremely important sales. Such an action is made with the aim to foster the use of micro/nano technologies to make EU companies more competitive. By means of seminars, information on websites, newsletters and technical journals, brokerage and technology transfer events the project will promote EOIs and applications to EU Exploratory Awards, CRAFT and RTD Projects.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'New concepts for high efficiency and low cost in-line manufactured flexible CIGS solar cells' (HIPOCIGS), addressing dissemination and exploitation.

assistant: **Impact**

The Cu(In,Ga)Se2 (CIGS) on glass technology is already heading towards industrial maturity, but to meet the production cost target of below 0.6 €/Wp in mid-term and below 0.4 €/Wp in long-term, development of highly efficient flexible modules is an attractive option. The ultimate advantage of thin-film technology is the possibility of monolithically connected flexible modules produced with high speed roll-to-roll manufacturing systems. Partners of this proposal have already demonstrated a record efficiency of 14.1% for cells on polyimide and >15% efficiency cells on metal foil using “static deposition” processes. However, transfer of “static deposition” process to “in-line deposition” on moving substrates brings additional challenges for control of layer composition and interfaces. Choice of appropriate substrate and deposition processes to overcome problems of thermal mismatch-related stress are important for high performance and monolithic cell interconnection. The main goal of the project is to develop innovative flexible substrates and deposition processes suitable for the in-line and/or roll-to-roll production of highly efficient solar modules using thinner (< 1 micron) CIGS absorbers and with potential for production costs below 0.6 €/Wp in future. The objective will be achived by developing novel concepts in growth of “high quality” layers and interfaces for efficiency improvement, aiming a new world record efficiency of 16% on polyimide and low-cost metal (mild steel and Al-based) foils. Also, the implementation of in-line compatible buffer, improvements in interconnect technologies and application of multifunctional top layer will lead to an advancement towards roll-to-roll manufacturability of integrated solar modules. This project will help research instituti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Analysing the impact of health system change in the eu member states (IMPACT)', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

Policy makers in all of the EU countries are concerned with the issues of equity in the financing, access and outcomes of health care; locative efficiency across the public sector generally and the health services specifically; technical efficiency within the health sector; purchaser and provider accountability and responsiveness; and the relative contribution of health care to health, as compared to other health determinants. Policy makers have made changes to the health systems in all of the EU countries, with the intention of generating improvements in relation to the issues listed above. However, there has not been systematic comparative study of the effects of these changes across the EUcountries. We propose to establish a European research team to undertake systematic analysis of the health sector changes implemented in the EU countries over the last ten years, in an analytical research framework.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Morbidity due to Loiasis: population-wide evaluation and identification of pathogenic mechanisms' to be submitted under Horizon 2020.

assistant: **Abstract**

Loiasis, an infectious disease caused by the parasitic worm Loa loa, affects more than 15 million individuals in central Africa, and more than 100 million people are potentially exposed to infection. Since its first description in 1770, the international scientific community has considered this filarial disease as benign. I recently demonstrated that loiasis significantly reduces the life expectancy of infected people. I aim to definitively shift the prevailing paradigm of benign loiasis by showing that it can induce severe complications in various organs. I will conduct the first population-wide evaluation of morbidity in rural areas of Central Africa by performing systematic examinations on 4,900 selected individuals. This sample size will enable accurate estimation of prevalences of cardiovascular and renal diseases and of functional asplenia. Our results may lead to the recognition of loiasis as a significant public health problem. Such recognition could motivate integration of loiasis into the WHOs list of Neglected Tropical Diseases. In addition, should loiasis be found to induce a functional asplenia, combating this disease could have a huge impact on the incidence and severity of other severe and common infections favoured by asplenia, such as malaria and pneumonia. Incidentally, specific recommendations regarding pneumococcal vaccination in loiasis-endemic areas could be made. Another possible consequence of our findings is changes in the management of people identified as having high levels of Loa loa infection during routine surveys or onchocerciasis elimination activities. Presently, these people are excluded from ivermectin treatment (because of the risk of post-treatment encephalopathy), and little is done to lower their level of infection. Confirmation th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Growth And Sustainability Policies for Europe' (GRASP), addressing dissemination and exploitation.

assistant: **Impact**

Growth And Sustainability Policies for Europe (GRASP) addresses European policy concerns associated with growth within a comprehensive yet coherent analytical framework. This framework is built on Aghion’s version of the Schumpeterian growth approach. It emphasizes quality-improving innovation in imperfectly competitive markets, but suggests optimal growth policy may depend as well on levels of technological (and financial) development, and on seemingly unrelated, yet relevant policies. The approach provides a multi-layered vision of the policy drivers of growth. The five layers address gaps in current European research on growth: R&D (the Lisbon focus); structural economic reform; legal, institutional and organizational reforms; global commitments, and the fiscal policy. The first layer focuses on economic assessments of innovation (property rights and incentive issues). The structural economic reform layer focuses on sectoral (infrastructure, education and social) and regional policies. The third layer examines the interactions between the law, institutions, and the drivers of innovation. Global commitment looks at trade policies and global environmental commitments. The fiscal layer focuses on government finance of any public good component of these layers and their effectiveness in contributing to growth. Each layer provides a multidisciplinary diagnostic of the quality of growth-related policies. Combining them allows us to construct a full “Schumpeterian growth diagnostic” to assess the effectiveness of public policies, and the adequacy and sustainability of growth in Europe. The GRASP consortium brings together theorists, applied econometricians, and institutional (law, politics and economics) researchers to pursue complementary, state-of-the-art analyses. CEPR’s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Development and evaluation of nutritional strategies to reduce and prevent obesity in shift workers' (SHIFT2HEALTH) under Horizon Europe.

assistant: **Objectives**

Shift work is an independent risk factor for the development of overweight and obesity. As shift workers represent a huge target group throughout many sectors in Europe obesity and associated diseases stress national health systems. Unhealthy food choices (snacking, high sugar intake, preferences for spicy and sweet-fatty foods) were reported for this group, which are likely the main causes for becoming obese. The underlying mechanisms for these changed eating patterns remain to be resolved. Potential explanations are alterations in metabolic health conditions (e.g. microbiome and inflammation), taste perception and circadian misalignment. Empirically proven solutions are urgently needed to benefit national health systems and reduce the development of obesity and increase the wellbeing of shift workers in the EU.This project aims to identify mechanisms and environmental and lifestyle factors leading to obesity in shift workers and to develop and evaluate products and strategies with consideration of the behavioural and relational level to support healthy eating patterns. The project will focus on both healthcare (female dominated) and industrial workers (male dominated), two major sectors where working in shifts is common. We will combine existing and new knowledge on nutritional, behavioural, perceptual and physiological determinants of (un)healthy food choices in a cross-section trial and consider personal needs and wishes. Based on the latter results, promising strategies, technical solutions and products will be developed and tested within the target group in specific interventions. During all steps, stakeholders (health work organisations, shift workers` representatives, companies, policy makers and scientists) will be involved. With the results, new insights in th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Programmable Readers, Writers, and Erasers of the Epigenetic Cytosine Code' to be submitted under Horizon 2020.

assistant: **Abstract**

Human DNA contains two types of biologically instructive information: the canonical nucleobases A, G, T, C, and the epigenetic nucleobases mC, hmC, fC, and caC. Canonical nucleobases encode the identity of all RNAs and proteins that are synthesized by a cell, whereas epigenetic nucleobases regulate this synthesis. This regulation shapes the phenotype of cells, and its perturbation is a key trigger of cancer.Canonical nucleobases can be decoded in a programmable manner by nucleic acids and their analogs via Watson-Crick-base pairing, and the simplicity of this recognition has enabled revolutionary developments in the biological sciences. In contrast, comparable developments in epigenetics have not yet been possible, since a molecular scaffold with  programmable recognition of epigenetic nucleobases does not exist. We will establish the first class of molecules capable of the expanded programmable recognition of both canonical and epigenetic DNA nucleobases in vitro and in vivo. This is based on transcription-activator-like effectors (TALEs) that consist of four types of concatenated modules, each of which recognizes a canonical nucleobase. We have recently reported the detection of single epigenetic nucleobases by TALEs. In this project, we will 1. engineer a toolbox of TALE modules with selectivity for C, mC, hmC, fC, and caC,2. employ them for TALE-based in vitro typing and profiling (reading) of cancer biomarker mC/hmC, and 3. design photoactivatable TALE-fusions that enable the writing and erasing of mC at user-defined genomic loci in vivo with spatiotemporal resolution. This will provide the first insights into the dynamic effects of de novo editing on chromatin regulation, and enables the imprinting of regulatory states.Given the central role of epigenetic nucleoba
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'All-steel external frame for the non-disruptive seismic retrofit of existing reinforced concrete buildings' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The state-of-the-art review in seismic retrofit of existing reinforced-concrete (RC) buildings indicates that a technology that isnon-disruptive and easy to implement, achieves simultaneous control of drifts and accelerations, and overcomes majorissues related to low concrete strength, poor reinforcement details, and vulnerable RC columns, has never been described inthe literature or in seismic design codes (e.g. Eurocode 8). The ambitious main objective against the background of thestate-of-the-art of the project is to develop such a retrofit technology. In particular, the project will develop a non-disruptiveretrofit scheme using an external, modular, steel frame as a facade close and in parallel connected to frames of the existingRC building. The external steel frame will have chevron braces to support energy dissipation devices, and, connectors toachieve horizontal coupling with the existing RC building. Strategically, the energy dissipation devices will be visco-plasticdampers, i.e. novel devices that will offer visco-elastic damping output under low-to-moderate earthquake intensities andfriction damping output with a predefined limit on their peak force under high seismic intensities. The project will developsophisticated yet practical structural details and a simplified seismic design procedure for the external steel frame. All thesewill be achieved through a carefully planned integrated experimental and numerical research program involving constitutivemodelling, nonlinear finite element analysis, and shaking table tests. The proposed retrofit scheme constitutes a solidcontribution to earthquake engineering that is expected to raise major international scientific and industrial interest.


**Keywords:** seismic, concrete, retrofit, steel frame
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Development of a multidisciplinary platform for the screening of new preventive and therapeutic strategies against oral mucositis' (2007-2013) under Seventh Framework.

assistant: **Objectives**

Both from the European Centre for the Validation of Alternative Methods and worldwide, there is a general call for the reduction, refinement or replacement of the use of laboratory animals. However, while in vivo animal models of chemotherapy and radiotherapy-induced oral mucositis have been successfully established, alternative methods such as in vitro tools for mucositis are still missing.Oral mucositis is a severe side effect of both chemo- and radiotherapy and is the cause of inflammation of the mucosa of the mouth. Symptoms of mucositis vary from pain and discomfort to an inability to tolerate food or fluids. Apart from being treatment limiting, also the quality-of-life of patients and the economic costs of supportive therapies are of significant concern. Given that hundreds of thousands of patients worldwide are affected by mucositis annually, a significant need for effective therapy exists. However, there is no actual treatment. Therefore, new tools are urgently required to allow a rapid and high-throughput screening of new-generation anti-mucositis drugs and strategies.The objectives of this project can be summarized as follows: 1. Generation and critical evaluation of an innovative high-throughput in vitro model of oral mucositis; 2. In vivo validation of the in vitro model using established animal models of chemo/radiotherapy-induced mucositis; 3. Exploration of the in vitro and in vivo tools to identify new biomarkers and risk factors of mucositis in order to anticipate animal and human chemo/radiotoxicity and to enhance anti-mucositis drug screening.The set up of the platform requires an international and a multidisciplinary approach, involving prominent experts in the mucositis, cancer biology and medical microbiology field and a strong interaction with the