RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Astrochemistry of old stars: direct probing of unique chemical laboratories'.

assistant: **Innovation**

The gas and dust in the interstellar medium (ISM) drive the chemical evolution of galaxies, the formation of stars and planets, and the synthesis of complex prebiotic molecules. The prime birth places for this interstellar material are the winds of evolved (super)giant stars. These winds are unique chemical laboratories, in which a large variety of gas and dust species radially expand away from the star.Recent progress on the observations of these winds has been impressive thanks to Herschel and ALMA. The next challenge is to unravel the wealth of chemical information contained in these data. This is an ambitious task since (1) a plethora of physical and chemical processes interact in a complex way, (2) laboratory data to interpret these interactions are lacking, and (3) theoretical tools to analyse the data do not meet current needs.To boost the knowledge of the physics and chemistry characterizing these winds, I propose a world-leading multi-disciplinary project combining (1) high-quality data, (2) novel theoretical wind models, and (3) targeted laboratory experiments. The aim is to pinpoint the dominant chemical pathways, unravel the transition from gas-phase to dust species, elucidate the role of clumps on the overall wind structure, and study the reciprocal effect between various dynamical and chemical phenomena. Now is the right time for this ambitious project thanks to the availability of (1) high-quality multi-wavelength data, including ALMA and Herschel data of the PI, (2) supercomputers enabling a homogeneous analysis of the data using sophisticated theoretical wind models, and (3) novel laboratory equipment to measure the gas-phase reaction rates of key species.This project will have far-reaching impact on (1) the field of evolved stars, (2) the understanding
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Recyclable Energy-Efficient Rare-Earth Nitrides Power Electronics'.

assistant: **Concept**

REGEN-PE is driven by the vision to revolutionize power electronics by developing high-quality YAlN layers that not only enable affordable ultra-efficient performance but also promote sustainability through recycling. To achieve this ambitious goal, we adopt an ambitious approach that combines material density functional theory (DFT) simulations, sputtering and MOCVD for epitaxy, along with chemical and optical characterization techniques for material development. The project includes the successful integration of YAlN into cutting-edge electronic device structures, projected to surpass the GaN performance limit, which requires their design, fabrication, and electrical characterization. However, what sets the REGEN-PE project apart is its unwavering commitment to sustainability. By developing a novel method for material recovery, we aim to establish a precedent for recyclable semiconductor technology. REGEN-PE promotes a circular engineering approach, which sets the stage for the future of high-performance green power electronics.


**Keywords:** Circular engineering, nitrides, semiconductor recycling, power transistor, Yttrium aluminum nitride
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'LOCALITY - Nature-positive aLgae-based fOod, agriCulture, AquacuLture and textIle producTs made in North and Baltic Sea ecosYstems' under Horizon Europe.

assistant: **Concept**

LOCALITY will implement local, innovative, and sustainable value chains, supporting the interaction of the algae value chain actors with relevant waste stream producing industries. Three regional ecosystems will be strategically developed in key regions considering strong and active business on which circularity and sustainability will be improved by the reutilization of wasted nutrients for algae cultivation. These ecosystems will be positioned in the Baltic and North Sea bordering countries but multi-perspectively supported by other R&D and  industrial experienced partners in sustainable algae production. The biomass will be processed using a biorefinery approach and raw and treated ingredients applied in the food, aquafeed, agriculture, and textile markets. An integrative methodology involving R&D partners, industry, and SMEs will work in each market sector to develop innovative and sustainable algae-based products. The consumer readiness for the designed products will be assessed, and significant constraints and legal barriers will be identified. Those will be evaluated and integrated into the business model to prepare a successful market implementation and exploitation of the developed products. A dissemination and communication plan for maximum outreach to all relevant stakeholders will be implemented. The designed products will gain a strong position in the European marketplace in the coming years.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Holomorphic Blocks in  Quantum Field Theory: New Constructions of Exact Results' (HBQFTNCER), addressing dissemination and exploitation.

assistant: **Impact**

A central challenge in theoretical physics is to develop non-perturbative or exact methods to describe quantitatively the dynamics of strongly coupled quantum fields. This proposal aims to establish new exact methods for the study of  supersymmetric  quantum field theories  thereby  unveiling new integrable structures and fostering new  correspondences and dualities. We will develop a  new  cut-and-sew formalism to compute partition functions and  expectation values of observables  of supersymmetric gauge theories  on  compact manifolds through the gluing of   a fundamental set of building blocks, the holomorphic blocks. The decomposition of partition functions into holomorphic blocks corresponds to the geometric decomposition of compact manifolds into standard  simpler pieces. Similarly the gluing rules for the holomorphic blocks correspond to the geometric gluing rules. The key insight required to exploit the holomorphic block formalism is the  deep connection between supersymmetric gauge theories  and  low dimensional  exactly solvable systems such as 2d CFTs, TQFTs and spin chains.  Two and four dimensional holomorphic blocks can be reinterpreted as  conformal blocks in Liouville theory  through an established correspondence between supersymmetric gauge theories and Liouville theory. We will provide a similar realisation of three and five dimensional holomorphic blocks in  a new theory, a  q-deformed version of Liouville theory where the Virasoro algebra is replaced by the q-deformed Virasoro algebra.We will  develop this theory classifying the symmetries of correlation functions. These symmetries will be realised as gauge theory dualities, while  the language of the q-deformed Liouville theory will become a new powerful tool to investigate supersymmetric gauge theo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Low cost coherent light sources from nanoparticle array surface plasmon polariton systems', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Low cost coherent light sources from nanoparticle array surface plasmon polariton systemsLasers are ubiquitous sources of coherent light used in technology and everyday life, from optical communications enabling the internet to the lasers used in manufacturing, medical care and information storage. Coherent light sources with a small footprint, that are ultrafast and low cost, have low energy consumption could be used in sensor, switch and biomedical applications. Based on recent results of the PI's ERC Advanced project, nanolasers (lasers operating below the diffraction limit) that utilize non-radiative, so-called dark states have recently been demonstrated with organic materials. We have also just achieved a Bose-Einstein condensate (BEC) of photons in a similar system, which produces coherent light like a laser, but its formation mechanism is different: thermalization followed by bosonic stimulation, instead of just stimulated emission as in a laser. Thus, the usage and operation conditions of a luminous BEC can be complementary to a laser. This project will make such novel nanoscale coherent light sources cheap enough to be used in practical applications and demonstrate their use for example in sensor systems.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Changing landscapes: hormonal fluctuations and neurocognitive functioning across the female lifespan' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Puberty, menstrual cycle, and menopause are all critical periods in a female’s life characterized by drastic changes in sex hormone concentrations. These periods are also associated with changes in cognitive, affective and social processing as well as an increased risk of depression and anxiety, stressing the need to advance our understanding of effects of hormonal fluctuations on females’ well-being across the lifespan.A central process directly associated with cognitive, affective, and social functioning is performance monitoring. Adequate processing of errors, reward, and feedback is essential for efficiently adapting to a changing environment in everyday life. Gender and age effects exist for these processes and disturbances have been linked to anxiety and depression, making performance monitoring an important topic in the investigation of neurocognitive functioning across the lifespan. However, research so far has largely ignored the effects of fluctuating hormonal levels.To answer the outstanding question how changing hormonal concentrations affect neurocognitive functioning in women, I will employ a unique multi-disciplinary methodology combining longitudinal, psychopharmacological, and neuroimaging techniques. I will address the current gaps in our knowledge using a novel combination of three approaches: (1) a lifespan approach that includes female participants from late childhood to late adulthood, (2) a social approach that moves beyond the non-social focus of performance-monitoring research, and (3) a psychopharmacological approach that focuses on the interactions between the relevant exogenous and endogenous neurotransmitters and hormones for the first time.The project represents a turning point in our understanding of the effects of naturally occurring horm
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'NATURAL INTRAOCULAR PHOTOACTIVATION OF COMPOUNDS TO FIGHT RETINOPATHIES' under Horizon Europe.

assistant: **Concept**

Retinopathies constitute an extreme societal and socioeconomic burden that is expected to increase with an aging population and the increased prevalence of diabetes. These diseases, including age-related macular degeneration and proliferative diabetic retinopathy share neovascularization as a common etiology involving the pathological growth of retinal capillaries leading to blindness if left untreated. Current treatment modalities involve specialized injections into the eye that require not only outpatient visits to specialized treatment centers but are also associated with significant adverse effects. Orally bioavailable medications could revolutionize the treatment of retinopathies, by reducing adverse effects, sustaining vision, lowering the direct and indirect financial burden associated with these diseases, and increasing access to healthcare. Inspired by this idea, we have developed an approach that can be exploited to target essentially any therapeutic molecule to the eye. Our novel strategy of drug targeting will not only enrich the modified molecules in retinal tissue but will also reduce the therapeutic oral dose compared to existing anti-angiogenic therapy in cancer thereby increasing the safety of the treatment. This is achieved by absorbing a minute amount of the chemically and biologically stable molecules resulting in an extremely low plasma concentration and relying on a biological mechanism in the eye to activate the molecules to tether them to retinal target receptors and thereby extracting them from the blood. In the present application, we propose to demonstrate proof-of-concept of this strategy by modifying inhibitors of the vascular endothelial growth factor receptor (VEGFR). VEGFR is an endothelial receptor tyrosine kinase that is a key mediator
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Manipulating folding, assembly and disassembly of protein complexes - from molecule to disease' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

ManiFold is organised by researchers and teachers of the Bijvoet Graduate School for Biomolecular Sciences to achieve 3 key aims: (i) Moving the Bijvoet towards a Graduate School with annual rhythm and specific recruitment moments. (ii) Centering the research around focus areas to stimulate synergies. (iii) Strengthening the links of the School to private enterprises and international partners. ManiFold aims to extend its impact to the entire Bijvoet School by creating a coherent group of selected students that gel around one theme, large enough that we expect the group to have a strong influence, but such that it fits the capacity of our excellent educational programme. The Bijvoet groups have a longstanding track record in structural biology and outstanding expertise in large-scale infrastructure. In ManiFold, we focus our studies on protein folding and misfolding events at various levels, focusing on conceptual advances regarding the folding of newly-synthesized proteins, the assembly and disassembly of protein oligomers and complexes, conformational changes of proteins upon activation or deactivation, allosteric effects, protein misfolding and amyloid formation, the activity of molecular chaperones on those processes, and the monitoring of protein-protein interactions at the proteome level. The coherent class of students working on this multidisciplinary theme will allow us create synergisms and increase the quality of our education. From the joint effort on this topic we expect a lasting impact on training in our Bijvoet School, our international position and on the links of our School with the private sector.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Low Cost, Low Power, Gas and Reaction Sensors using Thick Firm Printed Lamines' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

Throughout all sectors of industry technical and production departments are investing in and seeking miniaturization of sensing devices. This is true of the medical profession where new and more intricate surgical procedures, treatment methods and diagnostics are seeking rapid. accurate and low cost sensing devices for both gases, dissolved compounds and reaction endpoints.. Extec has obtained an established reputation for innovation within the Thick Film Hybrid industry during the last 9 years, and have exploited this technology in establishment of an experirnental low power, low cost CO gas sensor. This is achieved by altering the materials content of a cofired suspended laminate within a small (less than 1/100 the size of a conventional detector strip) sensing element. It is the purpose of this proposed project to extend the application of thick film laminate sensors to the development of small, low cost, highly sensitive sensor devices with particular emphasis to the medical and process control industries.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Matter and strong-field gravity: New frontiers in Einstein’s theory' to be submitted under Horizon 2020.

assistant: **Abstract**

Gravity is the weakest but the most intriguing fundamental interaction in the Universe. In the last decades a formidable intellectual effort has shown that the full-fledged geometric nature of gravity offers much more than a beautiful description and understanding of all stellar and galactic. In the quest for the ultimate theory of gravity, new and spectacular connections between high-energy physics, astrophysics, cosmology and theoretical physics have emerged. Triggered by breakthroughs at the observational, experimental and conceptual levels, strong gravity physics is experiencing a Golden Age, making it one of the most active fields of research of the 21st century. My group in Lisbon has been involved in groundbreaking research into the nature of strong-field effects in curved spacetime with applications in various fields, thus establishing international leadership in the field. This proposal aims at understanding, via perturbative techniques and full-blown nonlinear evolutions, the strong-field regime of gravity, and includes challenging nonlinear evolutions describing gravitational collapse, compact binary inspirals and collisions in the presence of fundamental fields. The proposed programme will significantly advance our knowledge of Einstein's field equations and their role in fundamental questions (e.g. cosmic censorship, hoop conjecture, spacetime stability, no hair theorems), but also its interplay with high energy, astro and particle physics (testing the precise nature of the interaction between compact objects and matter --such as dark matter candidates or accretion disks-- and its imprint on gravitational wave emission, understanding gravitational-led turbulence,etc).This is a cross-cutting and multidisciplinary program with an impact on our understanding o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Smooth muscle cell modulation by the MaR1-LGR6 duo: novel role in the resolution of human cardiovascular inflammation.' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Atherosclerotic cardiovascular disease (ASCVD) is a progressive disease characterized by aberrant immune activation and chronic vascular inflammation as a result from a failure in the resolution phase. However, the mechanisms responsible for this dysregulation are not well understood. Little is known about the role of smooth muscle cells (SMCs) in regulating resolution of inflammation, an active process orchestrated by endogenous specialized proresolving lipid mediators (SPMs). These include the maresin family, and in particular maresin 1 (MaR1), which was recently shown to be a specific activator of LGR6. Despite the potent anti-inflammatory and proresolving actions of MaR1 in murine models and human cells, its role in ASCVD remains uncovered. Hence, this proposal aims to elucidate the role of SMC-derived resolution of inflammation in ASCVD, and the impact of MaR1-LGR6 in stimulating resolution. Specifically, I will focus on the molecular mechanisms of MaR1-LGR6 signaling, mainly on the phagocytic capacity of SMCs. I will employ mechanistic and functional assays in human SMCs, as a proxy for its potential in plaque “clearing” and plaque stabilization. I will characterize the expression of LGR6, by mass spectrometry imaging, and the biosynthesis of MaR1 in human atherosclerotic tissue (local) and identify indicators in blood samples (systemic) by LC-MS/MS-derived lipidomic profiling of human samples, in to obtain a profile of systemic lipid biomarker(s) that reflects the local abundance of SPMs or their receptors. This could be used to design personalized proresolving prevention in prone-to-CVD individuals. Lastly, I will investigate the SMC phenotypic modulation by MaR1-LGR6 in a LGR6-specific SMC-deletion ASCVD mouse model. Deciphering the SMC-mediated resolution prog