RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Non-invasive decoding of cortical patterns induced by goal directed movement intentions and artificial sensory feedback in humans'.

assistant: **Objectives**

In Europe estimated 300.000 people are suffering from a spinal cord injury (SCI) with 11.000 new injuries per year. The consequences of spinal cord injury are tremendous for these individuals. The loss of motor functions especially of the arm and grasping function – 40% are tetraplegics – leads to a life-long dependency on care givers and therefore to a dramatic decrease in quality of life in these often young individuals. With the help of neuroprostheses, grasp and elbow function can be substantially improved. However, remaining body movements often do not provide enough degrees of freedom to control the neuroprosthesis.The ideal solution for voluntary control of an upper extremity neuroprosthesis would be to directly record motor commands from the corresponding cortical areas and convert them into control signals. This would realize a technical bypass around the interrupted nerve fiber tracts in the spinal cord.A Brain-Computer Interface (BCI) transform mentally induced changes of brain signals into control signals and serve as an alternative human-machine interface. We showed first results in EEG-based control of a neuroprosthesis in several persons with SCI in the last decade, however, the control is still unnatural and cumbersome. The objective of FEEL YOUR REACH is to develop a novel control framework that incorporates goal directed movement intention, movement decoding, error processing, processing of sensory feedback to allow a more natural control of a neuroprosthesis. To achieve this aim a goal directed movement decoder will be realized, and continuous error potential decoding will be included. Both will be finally joined together with an artificial kinesthetic sensory feedback display attached to the user. We hypothesize that with these mechanisms a user will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Hydrogen Production from Waste', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

HyWay aims to synthesise hydrogen rich syngas from low cost carbon source, and eliminate the environmental issues from conventional waste management (e.g., landfill or incineration). HyWay advances the state-of-the-art in carbonaceous waste management especially plastic waste, waste tires, waste biomass and crude glycerol for hydrogen production. The overall aim of the HyWay is to establish long-term consolidated research collaborations between the participating institutions with complementary expertise and knowledge to design and develop carbon-neutral, scalable, and socially acceptable pathways to sort and convert waste to hydrogen-rich syngas as part of next generation sustainable fuels. Through secondments, workshops, training, webinar series, and industry-focused events, HyWay produces multiple avenues for career development, cross-sectoral experiences, and academic training in a multi-cultural and interdisciplinary environment. Research results are translated into training materials, including formal academic and industry courses on waste sorting, chemical recycling technologies, process modelling, machine learning, techno-economic analysis and life cycle analysis for postgraduate students, early-stage and experienced researchers and industry; training tutorials for industrial and technical staffs; and creating the basis for developing academic textbooks for the wider research community and possibly in undergraduate module delivery. There is also a focus on transferable skills, with dedicated training activities specially designed to facilitate personal development, technological and communication skills. HyWay delivers through the effective collaboration of 7 member state/associate country universities and companies, and eight third country universities and compa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Effects of non-equilibrium coulomb correlations in semiconductor quantum dots' under Fourth Framework.

assistant: **Concept**

Research objectives and content The focus of this project is on the effects of Coulomb interactions on the optical properties of semiconductor quantum dots. Quantum dots offer a unique laboratory to study the effects of correlation, which become more and more pronounced as the interaction between carriers is enhanced due to their localization. A realistic description of these systems (and their possible applications in optoelectronic devices) is precluded if one adopts oversimplified single-particle models without taking into account the effects of correlation. In our analysis of quantum dots, we intend to use as a starting point an approach that was developed by the group in Modena and applied successfully to quantum wires. This is based on the numerical solution of multiband Semiconductor Bloch equations, which allows to perform quantitative calculations of the optical spectra of realistic quantum wires. These studies have allowed to point out the dominant role of Coulomb correlation on the optical response of realistic wires. In this project it is planned to perform a similar analysis for quantum dots, and to extend the analysis to time-dependent scenarios which can be directly compared to experimental results obtained by femtosecond spectroscopy. The main part of my Ph.D. thesis is concerned with a formal description of free-carrier screening in non-equilibrium systems: thus, it will be possible to take advantage of such formalism within the present project. Training content (objective, benefit and expected impact) The main contributions to my training will be the opportunity to learn about the theoretical modelling of low-dimensional structures. In particular, the experience of the host institution in the field of ultrafast optical response of semiconductor nanostr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'COatings for BipolaR plAtes' (COBRA), addressing dissemination and exploitation.

assistant: **Impact**

Several automotive OEMs have announced plans for the commercialization of fuel cell vehicles from 2014/15. While this is a clear signal for the readiness of the automotive market, durability, efficiency, power density and cost of the fuel cell stack need further advancements and in some cases substantial improvement in years to come.Industrial fuel cell development in Europe lacks both state-of-the-art stack components and competitive stack suppliers for automotive application. Only a few European component suppliers can deliver mature state-of-the-art stack components such as bipolar plates with the specifications requested by the AIP of the FCH-JU.The COBRA proposal aims to develop best-of-its-class bipolar plates for automotive stacks with superior corrosion resistance and durability while meeting commercial target cost. The project has a multidisciplinary character which implies joint efforts of specialists from various areas: chemistry, physics, material science, fuel cell engineering. Thus the COBRA consortium combines the collective expertise of bipolar plate and coating suppliers, system integrators and research institutes and thus removes critical disconnects between stakeholders.The scientific objectives of this project are elaboration and characterization of low-cost new functional coated bipolar plates highly resistant to corrosion with low contact resistance. The project will contribute in defining new coatings combining passivity and conductive properties by i) material selection, ii) screening of the coating elaboration process, iii) performance evaluation in stack configuration in real operating conditions, iv) techno-economical evaluation for large scale industrial production.Presence of key industrial players in the project and strict orientation towar
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Harvesting the power of a new model organism: stem cells, regeneration and ageing in Macrostomum lignano'.

assistant: **Objectives**

The ‘stem-cell theory’ of ageing posits that the functional decline in adult stem cells is one of the factors contributing to ageing. Importantly, the number of stem cells does not diminish with age in many tissues but rather there are intrinsic and extrinsic changes that affect their functionality. Is it possible to reverse these changes? Experiments in the emerging model Macrostomum lignano suggest that this is indeed the case. Remarkably, induced regeneration in this animal leads to extended lifespan: repeated amputation, followed by regeneration, results in animals that live far beyond the median lifespan of 205 days. Regeneration in M. lignano is facilitated by stem cells called neoblasts, and it appears that regeneration resets the ‘ageing program’ in these animals.Due to its high regeneration capacity, small size, transparency and clear morphology, ease of culture, short generation time and amenability to genetic manipulation, M. lignano has great potential as a model organism for stem cell research. I have recently started developing genomic and genetic tools and resources for this model, and at present my group has generated a draft genome assembly, produced de novo transcriptome assembly, discovered several neoblast marker genes and made the first stable transgenic lines in this animal.Here I propose to study molecular mechanisms underlying rejuvenation in M. lignano, and to further advance M. lignano as a model organism through development of missing genetic tools and resources. I will address how young, aged and regenerated worms differ in their gene and small RNA expression profiles, and what are the differences and variation levels between neoblasts of young, old and regenerated animals. The biological roles of the identified candidate genes and their effe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Bio Innovation of a Circular Economy for Plastics' (BioICEP) under Horizon 2020.

assistant: **Objectives**

The Bio Innovation of a Circular Economy for Plastics (BioICEP) is a pan European-Chinese collaboration formed to reduce the burden of plastic waste in the environment. Different mixed plastic pollution environments are represented, with specific partners selected which have the expertise and facilities to carry out the necessary technical innovations. A number of innovative booster technologies are at the core of this solution accentuating, expediting, and augmenting mixed plastics degradation to levels far in excess of those current achievable.  Our approach is The Bio Innovation of a Circular Economy for Plastics (BioICEP) consortium is a pan European-Chinese collaborative formed to reduce the burden of plastic waste in the environment. The countries have been selected to represent different mixed plastic pollution environments, with specific partners selected which have the expertise and facilities to carry out the necessary technical innovations. Three innovative booster technologies are at the core of this solution accentuating, expediting, and augmenting plastics degradation to levels far in excess of those current achievable.  Our approach is a triple-action depolymerisation system where plastic waste will be broken down in three consecutive processes:  1) mechano-biochemical disintegration processes, including a new proprietary sonic-green-chemical technology to reduce the polymer molecular weight of the base polymer to make it amenable to biodegradation; 2) biocatalytic digestion, with enzymes enhanced through a range of innovative techniques including accelerated screening through novel fluorescent sensor and directed evolution; and 3) microbial consortia developed from best in class single microbial strains, which combined leads to highly efficient degradati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Deciphering the code of gene regulation using massively parallel assays of designed sequence libraries' (GENEREGULATION) under Seventh Framework.

assistant: **Objectives**

Many gene expression changes that are associated with disease states have in turn been linked to changes in the genes’ regulatory regions. However, without a ‘regulatory code’ that informs us how DNA sequences determine expression levels, we cannot predict which sequence changes will affect expression, by how much, and by what mechanism.Here, we aim to arrive at a mechanistic and quantitative understanding of how expression levels are encoded in DNA sequence using a combined experimental and computational approach. To this end, we will construct libraries of >50,000 sequences, fuse them to fluorescent reporters, and genomically integrate them to yeast or human cells. We will then develop methods for accurately measuring, in parallel, the expression of each fused sequence within a single experiment, and for measuring the DNA binding state of each sequence at single cell resolution, resulting in ~1000-fold increase in the scale with which we can study the effect of sequence on expression.Notably, we will design our experimental system to be modular, allowing us to propose a highly ambitious yet realistic plan in which we will study the effect of sequence on (1) transcriptional and (2) post-transcriptional regulation; (3) Unravel the effect of genetic variation across human individuals on expression; (4) Quantify how cellular fitness depends on the expression level of individual endogenous genes; and (5) Construct a predictive model of the effect of DNA sequence on expression.Each of our libraries should provide novel insights into a different aspect of gene regulation, leading to new means by which we can interpret whole genome sequencing, which is rapidly being collected for many individuals. In particular, our unified model should allow us to predict expression changes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Nanoscale analysis of symmetry and molecular membrane topography' under Horizon Europe.

assistant: **Concept**

The compositional and structural asymmetry of cell membranes remains one of the greatest knowledge gaps in cell biology. Cells invest significant amount of energy to establish and maintain inter-leaflet asymmetry; however, the physiological roles of bilayer lipids during dynamic cellular processes in eukaryote membranes remain poorly understood, mostly due to the limits of previously available methodologies and the complexity of lipid membranes. Current knowledge originates from indirect and perturbing techniques (i.e. enzymatic digestion and mass spectrometry) which significantly limits the applicability to certain cell types with no internal membranes. Moreover, these bulk methods do not provide spatial information on lipid asymmetry which prevents detailed observation of subcellular changes during dynamics processes such as host-pathogen interactions.In this project, I will develop a method to directly visualize and quantify membrane asymmetry, which will be applicable to study any cell type as well as intracellular membranes. Recent advances in super-resolution microscopy, including my latest publications, paved the way for direct observation and quantification of lipid asymmetry. I will combine state-of-the-art isotropic expansion methods with super-resolution microscopy to visualize membrane lipids in individual leaflets of bilayers. To obtain further insights on the physiological role of membrane asymmetry, I will investigate changes in lipid asymmetry induced by infection with viral particles. The novel methods I will develop will significantly contribute to a better understanding of lipid asymmetry in biological membranes and its impact in cellular physiology and diseases mechanisms.


**Keywords:** super-resolution microscopy, expansion microscopy, dSTORM, STE
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Modeling Urban Growth Patterns in Central and Eastern Europe with Agent Based Systems and Cellular Automata' (MUGPCEE).

assistant: **Concept**

Suburbanization in Central and Eastern European cities has become the predominant form of metropolitan growth, undermining seriously the application of sustainable urban development principles in the region. The negative impacts of sprawl are just beginning to emerge as an area of public concern in the post-socialist cities where urban growth is managed through a mixture of uncoordinated and often conflicting policies. The proposed research project is aimed at investigating the impact of contemporary public policies on the patterns of urban growth in Central and Eastern European cities. The project will employ the latest theoretical and technological advances in urban growth modeling through the application of agent-based systems and cellular automata. The following objectives define the projects scope:  1. Developing an agent-based cellular automata model of urban growth applicable to the urban development context of post-socialist cities in Central and Eastern Europe. 2. Applying the model for evaluation of different urban growth scenarios based on existing and alternative public policies in select case studies from the region. 3. Using the model output to identify key policies for the effective control of urban sprawl and the application of sustainable development principles in managing the growth of Central and Eastern European metropolitan areas.  The project will be hosted by one of the world’s leading research institutions in the field of urban studies - the Center for Advanced Spatial Analysis at University College London. It is intended to provide the applicant with cutting-edge knowledge and scientific skills in a new (for the applicant) area of urban analysis. The experience from the project will become a stepping stone in setting up Dr. Stanilov’s future car
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'String algorithms'.

assistant: **Objectives**

Research objectives and content This research project aims to design, analyse and implement algorithms for combinatorial problems on strings (sequences of characters). The purpose of this proposal is to improve the time bounds of known algorithms for computing certain types of periodicity such as covers and edit distances in DNA sequences. It will also provide a new approach to computer vision by applying state-of-theart string algorithmic tools for decomposing and analysing occluded images i.e. images composed of objects where some may be obstructed by others. More precisely, the expected results are to prove sequential linear time algorithms concerning k-coverings and approximate repetitions, optimal parallel and sequential algorithms for analysing occluded images composed of objects with holes and non-convex objects and finally produce software packages relative to the above algorithms. Training content (objective, benefit and expected impact) The objective of the training is to pursue to completion a PhD in computer science. The proposed research will benefit from the expertise in the field of two-dimensional pattern matching from the host institution. This will enable the project to bypass some of the necessary preparatory work. Links with industry / industrial relevance (22) The implementation stage of the project will lead to a collaboration with the Human Genome Mapping Project for enhancing existing DNA sequence analysis software packages.