RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Trusted Biometrics under Spoofing Attacks'.

assistant: **Innovation**

The TABULA RASA project will address some of the issues of direct (spoofing) attacks to trusted biometric systems. This is an issue that needs to be addressed urgently because it has recently been shown that conventional biometric techniques, such as fingerprints and face, are vulnerable to direct (spoof) attacks.<br/>Direct attacks are performed by falsifying the biometric trait and then presenting this falsified information to the biometric system, one such example is to fool a fingerprint system by copying the fingerprint of another person and creating an artificial or gummy finger which can then be presented to the biometric system to falsely gain access. This issue effects not only companies in the high security field but also emerging small and medium sized enterprises (SMEs) that wish to sell biometric technologies in emerging fields.<br/>In particular the TABULA RASA project will:1. address the need for a draft set of standards to examine this problem,2. propose countermeasures such as combining biometric information from multiple sources,3. examine novel biometrics that may be inherently robust to direct attacks.<br/>The first issue of a draft set of standards will be addressed by analyzing the effectiveness of direct attacks to a range of biometrics, this will provide an insight as to how vulnerable the different biometric traits are to these attacks. The second issue of countermeasures will be explored in two lines, the first line of work proposes to combine multiple biometric traits to build a single system that is robust to direct attacks and the second line of work proposes to examine novel methods to perform liveness detection. Finally, novel biometrics which might be inherently robust to direct attacks, such as gait (the manner in which someone walks), v
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Human serum albumin nanoparticles for synergistic chemotherapy and oligonucleotide therapy against oncogenic lncRNAs in lung cancer' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Lung cancer remains the most frequently diagnosed and most lethal cancer, making this disease a huge socio-economic challenge. Therefore, new effective therapeutic approaches are urgently needed. Long non-coding RNAs (lncRNAs) are versatile molecules that influence crucial pathways in cancer progression. RP3-340N1.2 is a poorly investigated but highly overexpressed lncRNA in lung cancer, suggesting it plays a pivotal role in its progression. The fellow will investigate the role of RP3-340N1.2 in lung cancer and its application in targeted therapy.SyRNAlb aims to overcome the existing limitations of lung cancer therapy by developing clinically translatable human serum albumin-based nanoparticles (HSA NPs). HSA NPs will release therapeutic oligonucleotides and chemotherapeutics in cells to synergistically reduce the lung cancer burden whilst avoiding the development of drug resistance and detrimental side effects. SyRNAlb will support Horizon Europe's mission on cancer by increasing the knowledge in lung cancer biology, specifically by characterising the role of the oncogenic lncRNA RP3-340N1.2. Additionally, the fellow will address the Translational European Challenge by developing a cutting-edge therapy based on a novel, stable and scalable albumin nanoformulation that co-delivery chemotherapeutics and oligonucleotides against RP3-340N1.2.The knowledge generated in syRNAlb will expand our limited understanding of the role of RP3-340N1.2 in lung cancer progression and promote the development of an effective treatment. Furthermore, the expertise and tools generated can be customized for other diseases and other target lncRNAs.This ambitious multidisciplinary project will promote the candidate's career as a future leader by learning not only novel molecular and cellular bi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'High efficient localized photon sources' to be submitted under Horizon 2020.

assistant: **Abstract**

The goal of this project is the development of a novel, hybrid and scalable quantum photonic circuit that enable the generation of tunable, brightness and indistinguishable single photons on-demand by the deterministically integration of III-V quantum emitters coupled to a planar hyperbolic metamaterial (HMM) resonator-antenna. The implementation of the multilayered HMM over the semiconductor quantum dots (QDs) will be carry out by Micro/Nano Litography. The innovative design of this proposal will enable to ensure the coupling between the emitter and far-field radiation channels and will provide extremely high Purcell factor and brightness enhancement. While single emitters coupled to plasmonic waveguides have been widely studied, there are no experiments with HMM Resonator-Antenna in the literature, even when it is proved that is compatible with a wide variety of sources and capable of room temperature operation due to the broad bandwidth enhancement of spontaneous emission and directional photon emission.  Finally, HELPS project will contribute to the understanding of the novel applications and functionalities of HMM coupled to semiconductors nanomaterials.


**Keywords:** Metamaterials, Quantum photonics, micro-spectroscopy, single photon
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Tipping Points in Antarctic Climate Components', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The TiPACCs project will investigate the probability of sudden and large changes in the sea-level contribution from the Antarctic Ice Sheet that would result from passing tipping points in the marginal seas and at the grounding lines of the floating ice shelves that fringe the ice sheet. A comprehensive study of the triggering processes will reveal the likelihood of reversibility, while the study of ice-ocean feedbacks will provide insight into the threat of sudden sea-level rise. Modelling work will deliver parameter estimates of safe operating spaces, and linking these with Southern Ocean observations will contribute to the launch of early-warning indicators for dangerous levels of ocean-induced basal melting of the ice shelves. We will achieve these objectives using a suite of state-of-the art ocean-circulation and ice-flow models run by leading European research groups, greatly enhancing confidence in the results. The combination of numerical work with existing remote sensing and in-situ observations and paleo-reconstructions is ideal for defining the proximity of the simulated tipping points. With this work, we aim to provide a better understanding of key processes controlling the climate-Earth system that are critical for further improvement in climate projections and reducing uncertainty in climate sensitivity calculations. We will also assess more accurately the impacts of climate change related to the proximity, rate, and reversibility of tipping points in Antarctic climate components. Furthermore, future climate projections will benefit from our combined use of numerical models and paleo-reconstructions as they allow a better understanding of how the climate system worked during abrupt climatic transitions and under warmer or colder than present-day conditions
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Functional materials from on-surface linkage of molecular precursors', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

With the advent of self-assembly, increasingly high hopes are being placed on supramolecular materials as future active components of a variety of devices. The main challenge remains the design and assembly of supramolecular structures with emerging functionalities tailored according to our needs. In this respect, the extensive research over the last decades has led to impressive progress in the self-assembly of molecular structures. However, self-assembly typically relies on non-covalent interactions, which are relatively weak and limit the structure’s stability and often even their functionality. Only recently the first covalently bonded organic networks were synthesized directly on substrate surfaces under ultra-high-vacuum, whose structure could be defined by appropriate design of the molecular precursors. The potential of this approach was immediately recognized and has attracted great attention. However, the field is still in its infancy, and the aim of this project is to lift this new concept to higher levels of sophistication reaching real functionality. For optimum tunability of the material’s properties, its structure must be controlled to the atomic level and allow great levels of complexity and perfection. Complexity can be reached e.g. with hybrid structures combining different types of precursors. In this project, this hardly explored approach will be applied to three families of materials of utmost timeliness and relevance: graphene nanoribbons, porous frameworks, and donor-acceptor networks. Along the pursuit of these objectives, side challenges that will be addressed are the extension of our currently available chemistry-on-surfaces toolbox by identification of new reactions, optimized reaction conditions, surfaces, and ultimately their combination stra
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Rare Earth Free Innovative Truck Traction' (REFITT).

assistant: **Innovation**

Rare Earth Free Innovative Truck Traction (REFITT) will see the full commercialisation of HDSRM, a unique, rare-earth magnet free traction motor concept for use in electric commercial vehicles. The commercial vehicle sector is not well supported by Tier 1 suppliers of electric traction motors, necessary to see the wide spread adoption of zero emissions electric vehicles in our cities. This new traction motor technology has already been proven to TRL6 in a 7.5 tonne parallel hybrid truck and is currently being readied for trial in a range extended truck. REFITT will allow Newcastle University spin-out company, Advanced Electric Machines Ltd, to become such a Tier 1. HDSRM takes the benefits of Switched Reluctance Motor technology and overcomes its weaknesses, through the use of a patent-pending drive configuration, allowing a six phase motor to be driven from an industry standard three phase inverter. This configuration has been demonstrated to increase performance whilst reducing torque ripple and acoustic noise, to levels equivalent to machines which need rare earth magnets; but without the need to use these expensive materials which fall at the top of the EU's critical list. REFITT will support Advanced Electric Machines Ltd in fully proving this traction motor technology, enabling a full process of design for manufacture, undertaking extended vehicle trails in trucks and buses whilst also undertaken the off-vehicle testing to fully prove the system. The company will also prepare itself to become a supplier acceptable to OEMs, putting in place quality management systems and processes and establishing world class facilities. The company is already partnered with a Truck manufacturer and has established links with Bus, Taxi and even Boat builders. REFITT will therefore
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Monolithic cointegration of QD-based InP on SiN as a versatile platform for the demonstration of high performance and low cost PIC transmitters' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

MOICANA aims to deploy a versatile, low-cost and large-volume manufacturing transmitter PIC technology by monolithically integrating InP QD laser structures on a passive SiN waveguide platform and demonstrating a whole new series of high-performance cooler-less transmitter modules for a broad range of applications. MOICANA will invest in the best-in-class materials for the active and passive photonic functions, synergizing InP QD laser structures with the low-loss and temperature-tolerant SiN waveguide platform. It will grow InP QD layers directly on Si substrates and will proceed to Selective Area Growth on SiN chips, aiming at the fabrication and deployment of a whole new series of transmitter modules as monolithically integrated PICs: a) 25GbE SFP28 pluggable Directly Modulated Laser (DML), b) a WDM 100GbE QSFP28 pluggable DML, c) Externally Modulated Lasers, and d) a coherent tunable laser source. In this effort, MOICANA will deploy sophisticated integrated InP QD-on-SiN structures including 25Gb/s DMLs, low-linewidth DFBs and electro-optic modulators and will combine them into versatile and highly scalable transmitter layouts exploiting the rich and low-loss passive function portfolio of the SiN waveguide platform. Its transmitter PIC prototypes will be demonstrated in a broad range of applications in the areas of Data Center Interconnects, 5G mobile fronthaul and coherent communications, highlighting its versatility perspectives and its powerful credentials to form the transmitter technology for many-years-to-go.  Finally, MOICANA’s technology will be supported by an EDA software design kit library and PDKs that will be deployed withint its duration, paving the way for a standardized and fabless PIC transmitter eco-system with immediate market take-up capabilities
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Phase I trial in recurrent high-grade glioma: High-dose vorinostat with concurrent hypofractionated radiation therapy' (2007-2013).

assistant: **Concept**

High-grade gliomas are the most frequent type of primary brain tumor in adults. Despite optimal multi-modality treatment the disease almost always recurs, at which point median survival is less than a year. Vorinostat (suberoylanilide hydroxamic acid) is the first member of a new class of anti-cancer compounds - histone deacetylase (HDAC) inhibitors, that modulate global gene expression. The drug potentiates the anti-cancer activity of cytotoxic agents in a range of tumor types. The standard dosing schedule is low-dose drug for a long-duration. Recently ‘high-dose short-duration’ vorinostat in combination with chemotherapy has been shown to be well tolerated by subjects with colon cancer and leukemia.Radiation therapy kills cancer cells by inflicting DNA damage. Vorinostat potentiates radiation induced cell death (radiosensitization) through down-regulation of DNA repair. Clinical trials assessing combined low-dose vorinostat and radiation are in progress. In this proposal we investigate short-duration very high-dose vorinostat in combination with hypofractionated radiation therapy (RT) for recurrent glioma.Method: A phase I dose-escalation trial for subjects with recurrent glioma scheduled to undergo surgery followed by RT. Vorinostat will be administered both before surgery and post-operatively concurrently with RT. Tissue removed at surgery (exposed to vorinostat) will be compared with previously resected tumor from the same patient at the time of original diagnosis (unexposed to vorinostat), enabling analysis of how the drug modulates the levels of DNA repair enzymes. The overall goal of the proposal is to demonstrate the feasibility and biological rationale for this combined modality approach in recurrent glioma, laying the groundwork for a subsequent randomized ph
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Assessment of genetic variation in meat quality and the evaluation of the role of candidate genes in beef characteristics' (GEMQUAL) targeting Fifth Framework.

assistant: **Abstract**

Selective breeding in cattle has been very successful in increasing the quantity of production, but up to now there has been little selection for product quality. Identification of the genes involved in aspects of meat quality and the programmes to enhance meat quality and to account for regional variations in preference. This project will define the variation in meat quality using standardised measurements, in and between breeds of cattle representing the spectrum of diversity found in Europe when reared under standardised management conditions. The genetic component of the variation in specific measures of meat quality will be identified, and the contribution of candidate" genes and QTL to that variation tested using single nucleotide polymorphisms identified in the project as markers for alleles of the genes."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'The innovation coach: support action for innovation mainstreaming within the enlarged Europe'.

assistant: **Concept**

Innovation Coach will optimize the implementation of the 16 regions which are completing their RIS NAC projects through the improvement of policy implementation capacity (detailed and effective design of innovation support mechanism) and regional absorptio n (territories' implementation readiness). We will then exploit and deliver to NACs the best European expertise and knowledge in the field of innovation policy design and implementation. Our distinguishing asset will be the provision of a support package b ased on the following mix: International expert specialist advice (to supply detailed design and specialist know how tailored to the needs of action line to be implemented), capacity building support (to create the skills needed to ensure appropriate imple mentation of measures designed), absorption enhancement support (to ensure the appropriate exploitation of the tools and instruments to be launched by the regional beneficiaries) The final result will be a detailed action ready to use", a person in charge of implementation duly trained to follow the process. The support package will be used to carry on the implementation of at least 40 RIS NAC action lines. Individual support programmes will be enriched with horizontal activities to foster interregional ex changes and learning. Performance-based indicators will allow to assess the SSA and shape lessons to be used for innovation mainstreaming in other regions. We will achieve our ambitious targets exploiting the solid experience in designing and implementing innovation policy all over Europe and our unique ability to access wide basins of best European expertise and knowledge. TIl (grouping 260 innovation professional) and Eurada (with more that 150 RDAs members) are two leading EU association with a long expe rien
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Interlayer coupling on layered superconductors probed by transport measurements', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

We propose to develop methods to measure the decoupling transitions in layered superconductors with weak interlayer coupling of the Josephson type. Melting of the vortex lattice and interlayer coupling occur at different lines in the field-temperature plane of the high-TC materials. However the decoupling lines and their relation to the melting lines on the interlayer coupling strength have not yet been established. As model systems we will study artificial superconductor/insulator multilayers of NbGe/Ge and MoGe/Ge. These systems present the distinct advantage that the coupling strength can be easily tuned. To probe the decoupling transitions we want to measure the out-of-plane resistivity on samples structured into micron-scale pillars. We can also measure differences in vortex motion at the top and the bottom of non structured samples and compare these results with the previous ones.