RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The eq-net: to develop at a European level a standardised measure of health status and to facilitate its application' (EQ-NET) under Fourth Framework.

assistant: **Objectives**

Objectives:The aim of the EQ-net project is to support at a European level, the development, adaptation and application of the EQ-SD, an instrument to measure and value health status for use in clinical research, public health surveys and economic evaluation. The specific objectives of the EQ-net project will be: A central facility containing integrated datasets relating to characteristics of the EQ-SD and its application; at least 15 final harmonised translations of the EQ-5D in European languages; the production of guidelines for health state valuation, translations and application in economic and non-economic studies; to make available information packages and to support users through user conferences and training sessions.The aim of the EQ-net project is to support at a European level, the development, adaptation and application of the EQ-5D, an instrument to measure and value health status for use in clinical research, public health surveysand economic evaluation. The EuroQol Group originated in 1987 and comprised informal multinational and multidisciplinary research collaboration. After an initial phase of psychometric testing, the Group produced a generic, standardised, non disease-specific instrument for classifying and valuing health states. TheEQ-5D system classifies health states in terms of 5 dimensions, divided into three levels, which taken together defines a total of 243 health states. Moreover, by using a simple Visual Analogue Scale (VAS), the EQ-5D is capable of generating a single index figure of health status. Over the past years members of the EuroQol Group have been engaged in deriving values from different groups (e.g. patients and population samples) for EQ-5D health states in several European countries.It has been shown that values for specific
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Motor and cognitive functions of the monkey premotor cortex during free social interactions', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

A number of studies demonstrated that the primates’ premotor cortex (PM) plays a crucial role not only in organizing movement, but also in perceptual and socio-cognitive functions. However, these studies have been carried out in laboratory settings, which deeply limit the possibility to understand the neural mechanisms underlying natural behaviours. To solve this problem, I propose a new approach consisting in a two-steps chronic recording of monkey PM neurons: first, single neurons response properties will be characterized in a traditional, head-restrained laboratory setting; then, in the same session, the same neurons activity will be recorded wirelessly during free interactions of the monkey with its physical and social environment. The project will initially focus on neurons belonging to the forelimb representation of the ventral (i.e. areas F4 and F5) and dorsal (area F2vr) PM, putatively well known for their role in sensorimotor transformations, goal coding, representation of space, and recognition of other’s observed actions. The same paradigm will then be applied to the study of the mesial pre-supplementary area F6, a crucial bridge between prefrontal and PM regions whose role in socio-cognitive functions remains still virtually unknown. Finally, by simultaneous, chronic recording of neuronal activity from lateral and mesial PM, we will first assess the functional interactions between these areas in both laboratory and natural settings, and then we will probe causality in these interactions by chemically manipulating neuronal activity of one region (i.e. F6) while recording from the other one (i.e. F5). The project will reveal the role of premotor cortex in motor and social functions during natural behaviours. In addition, it might open up new possibilities for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Monitoring biodiversity changes associated with recent agroforestry developments in Southern Portugal - the use of avian communities as ecological indicators' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

The project will enable Dr Mark Bolton to join an existing research team in Portugal to provide expertise in ecological census techniques, data handling and statistical analysis. The research questions will focus on the changes in biodiversity in a variety of Portuguese habitats that result from current chances in agroforestry practices. Two agroforestry trends will be selected for analysis: the replacement of cork oak woodland with eucalyptus plantations in mountainous areas and the substitution of dry fruit orchards (e.g. almond, fig, olive) with irrigated citrus orchards, on the lowlands. Biodiversity will be assessed on three trophic levels: floral; primary level consumers (mainly invertebrates) and secondary Ievel consumers (avian species), and the use of bird communities as indicators of overall species diversity will be assessed for these habitats, in both the breeding and non-breeding seasons.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Translational aspects of the discovery of skull marrow – meninges connections' to be submitted under Horizon 2020.

assistant: **Abstract**

Neurodegenerative diseases (NDs) are labeled as the epidemic of the 21st century. The inflammation of the brain is a common pathology observed in many NDs. Here I aim to exploit our discovery of skull – meninges connections (SMCs) mediating immune cell trafficking into the brain to ease this healthcare burden. Using tissue clearing methods, we found that the skull (calvaria) bone marrow is directly connected to the brain meninges, a discovery that was also shown by an independent group around the same time. This finding suggests that the calvaria is involved in diverse brain pathologies. Easier accessibility of the calvaria compared to brain parenchyma also makes it an attractive region to target, which would alleviate hurdles of drug delivery into the brain, e.g., to control neuroinflammation. Furthermore, potential biomarkers in the calvaria reflecting pathologies of the brain could be easier and faster to detect. However, the detailed structural and cellular characteristics of the SMCs and the calvaria, and how they correlate and interact with neuropathology remain unknown. Here, we will utilize high-throughput technologies such as tissue clearing, single cell RNAseq, proteomics and unbiased analysis of data using deep learning to close this knowledge gap. We will use ischemic stroke and dementia models that are associated with acute and chronic neuroinflammation, respectively, and study both mouse and human tissues in parallel to validate potential clinical implications.This project will investigate followings:Aim 1 | Calvaria in physiological stateAim 2 | Therapeutic aspect: manipulation of calvaria to control stroke and dementia Aim 3 | Diagnostic aspect: calvaria imaging to monitor stroke and dementiaThus, the first in-depth investigation of the calvaria bone in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Contextualising behavioural change in energy programmes involving intermediaries and policymaking organizations working towards changing BEHAVIOUR'.

assistant: **Objectives**

This project aims to support the shift toward end-user services in European energy policy. It will (1) develop a sophisticated but practical model of end-user behaviour and stakeholder interaction (2) integrate knowledge of context (e.g., national culture and institutions), timing and actors into demand management practice (3) pilot the transfer of context-tailored demand side programmes from one European country to another (4) create a toolkit for practitioners to manage the social and technical change involved in demand management programmes (i.e., energy efficiency and renewable-based end-user generation). This toolkit will be sensitive to the influence of context, timing and actors, and will thus facilitate the cross-country transfer and adaptation to local context of European best practices. The toolkit will in particular address the diversity of conditions and behaviour patterns in old and new EU Member States. This project will work through intensive co-operation between researchers and intermediary organisations in the field of demand management (i.e., informative instruments, pilot projects, auditing and investment support, voluntary agreements, third-party financing schemes and the like). Such organisations include governmental or semi-governmental energy agencies, non-governmental organisations, consultancies and energy service companies. Together with these organisations, the project will evaluate and analyse behavioral responses to demand side measures, and test the transfer of demand side programmes from one European context to another. This collaborative project will create new knowledge on energy related end-user behaviour and will ensure that this knowledge is useful for practitioners and policy makers in different parts of Europe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'People, Space and Time: Understanding metaphors in sustaining cultural landscapes' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Growing up near Great Zimbabwe, I was always fascinated by the myths and legends associated with the site. However it was surprising that these stories never featured in my studies as an archaeology student. This essential contradiction is at the root of this project which seeks to address the significance of these myths and legends in understanding and managing cultural landscapes. More specifically its aims are to 1) map sacred landscapes through metaphors represented by myths, legends and folklore linked to the two places chosen as case studies; 2) explore how ‘metaphors’ sustain sacred cultural landscapes in traditional societies in Zimbabwe and Australia; and 3) examine how metaphors can be useful to archaeological research, the management of heritage places and ethical heritage practice. In this study, metaphor is the language used in defining certain elements of the landscape through stories by communities that revere them. Through this understanding, sites and artefacts are anthropomorphised to behave like people and to take physical characteristics of humans. The project utilises two sites as case studies: Great Zimbabwe (Zimbabwe) a cultural site revered by Shona communities living near it, and Uluru a natural landscape on which local Aboriginal communities have inscribed culture through metaphors. The study will have a practical purpose: understanding metaphor by both experts and other users to create new interpretations of sacred landscape that can reduce conflicts with communities that inscribe cultures on the landscape . I argue that to understand landscapes that are sacred, one has to understand the cultural and environmental metaphors of those communities that own them. Current approaches tend to divide landscapes into natural and cultural but emphasizin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Africa @ Work: Transformation of Employment 1920–2020' (AWORK).

assistant: **Concept**

The lack of productive and decent jobs remains one of the most pressing challenges in Sub-Saharan Africa (SSA). An estimated 82% of workers are engaged in informal occupations—primarily self-employed or in family work—leaving millions of workers vulnerable to poverty, economic shocks, and insecurity due to unstable jobs, low pay, and limited social protection. This scarcity of jobs fuels political and social unrest, including anti-government protests and coups, and drives migration to Europe. SSA’s young and rapidly growing workforce, projected to nearly double by 2050, underscores the urgent need to expand decent employment opportunities to alleviate poverty, enhance food security, and sustain economic growth.In this ERC project, I offer the first comprehensive, long-term analysis of employment patterns in Sub-Saharan Africa (SSA), reconstructing occupational trends by region and gender across 33 countries from 1920 to 2020. I examine how work evolved during key periods of transformation, including colonial agricultural expansion, post-independence state-led development, the Structural Adjustment Programs of the 1980s, and economic growth from 1995 to 2015. Key questions include: Why are agricultural jobs increasing in SSA while declining in other world regions? Why is the SSA informal sector disproportionately large, especially for women, who are 14 percentage points more likely than men to hold informal jobs? And to what extent can jobs in the expanding service sector provide a pathway out of poverty? By linking colonial and post-independence employment patterns, this project will uncover how economic transformations shaped informality, gender inequality, and stratification in the labour market. It also explores changes in work quality and social mobility, aiming to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Morphology, Energy and Climate Change in the City' (MECHANICITY) targeting Seventh Framework.

assistant: **Abstract**

Despite half a century of sustained research into the structure of cities, we still cannot answer the most basic questions of how their morphology is affected by the energy and income of their populations. We do not know if cities will become more compact or more spread out as energy usage changes due to global warming and as we switch to renewable energy sources. What we need is much more robust theory with applicable computer models for forecasting such impacts. Many of the rudiments involving agglomeration economics, growth theory, trade, nonlinear dynamics, and fractal geometry have already been put in place with the complexity sciences providing a framework for this new social physics. But so far, energy has been strangely absent. Here we will embrace this role, thus generating theory and models able to address what cities will look like if current predictions of climate change are borne out. We will organise the project into six related themes. First, we will extend theories of urban morphology based on fractals, scaling and allometry to incorporate energetics in analogy to transport and network processes. Second we will link these to statistical thermodynamics in spatial interaction and location modelling where energy, entropy, and accessibility are central. Third we will aggregate our theories to enable comparative analyses of city shape, compactness, energy use, and density. Fourth, we will explore different dynamic regimes building on self-criticality and bifurcation. Fifth, we will make these ideas operational building on our London Tyndall Centre model, and on related work in Phoenix and Shanghai. Last, we will construct a web-based laboratory for posing what if questions about climate change and energy balance using our theoretical and empirical models.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Magnetic alloys and compounds for ultra-high harmonics spin current generation'.

assistant: **Concept**

Limiting power consumption for massive data while increasing data processing speed and transfer rates requires the development of innovative architectures for logic, memory, and hyper frequencies applications. Spintronics brings some answers proposing solutions based on spin-orbit coupling. However, there is still a need to further reduce power consumption, simplify memory architectures, and close the THz gap. I propose unconventional experiments to develop magnetic-based platforms towards sub-THz spin current generation without the use of laser sources and gain access to the study of magnetic materials with high resonance frequencies.I formulate here new challenges presenting cutting-edge concepts involving spin-orbit coupling in magnetic alloys and compounds with magnetic Rashba interfaces. These will allow exploring and exploiting the ultra-high harmonics generation of spin currents, spin-orbitronics signals, in the sub-THz domain by tuning the ferromagnetic exchange and Rashba splitting.Based on these innovative concepts, MAGNETALLIEN has a twofold objective: i) to demonstrate that magnetic alloys and compounds, such as amorphous ferrimagnets and magnetic epitaxial Heusler, that possess strong spin-orbit coupling will lead to a new platform for efficient spin current self-production and, ii) will lead to the production of ultra-high harmonics spin pumping voltage up to tens or hundreds of GHz enabling various uses in new spin-orbitronics experiments. MAGNETALLIEN project will generate knowledge in spin current self-production and self-torque in magnetic alloys and compounds that will allow making decisive progress for less-energy-consuming architectures. Although of fundamental nature, demonstrating the existence of ultra-high harmonics signal which exploitation in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Development of freely available predictive models based on simple chemical descriptors', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

A system of optimal descriptors for modeling by means of quantitative structure property/activity relationships (QSPR/QSAR) biochemical endpoints will be developed. As representation of molecular structure, hydrogen filled graph (HFG), graph of atomic orbitals (GAO), simplified molecular input line entry system (SMILES), and International Chemical Identifier (InChI) will be examined. The GAO is an attempt to take into account atom structure in the QSPR/QSAR analyses.The GAO is an original innovation of the project. Endocrinal activity, carcinogenic potential, toxic endpoints will be examined as objects of the QSAR analyses with optimal descriptors based on four abovementioned representations of molecular structure. Special software for prediction of these biochemical and biomedicine endpoints will be developed. This software together with detailed instructions will be available for free download at special web site.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Accelerating drug and biomarker discovery through a new proteomic service: DrugPhosphoProfiler' (DrugPhosphoProfiler), addressing dissemination and exploitation.

assistant: **Impact**

At present there is a huge interest in the pharmaceutical industry to find and develop new drugs targeting protein phosphorylation and their related biological pathways, due to the critical implication of these processes in many pathologies. The high complexity of these phosphorylation-dependent cellular signalling network makes very difficult to have a clear idea about the mechanism of action of a particular drug as well as its side effects.  Unfortunately, existing approaches are unable to provide comprehensive, robust and quantitative data of cellular phosphorylation needed to support faster and more efficient drug discovery and development. Consequently, there is a large and unmet need in the pharmaceutical industry for identifying related therapeutic, toxicity targets and biomarkers, in order to develop better drugs. We are developing DrugPhosphoProfiler, an innovative mass spectrometry (MS)-based high-throughput platform for systematically measuring the effects of pharmaceutical agents on phosphorylation-dependent cellular networks in a proteome-wide and drug concentration-resolved manner. DrugPhosphoProfiler will be a unique, high-content drug discovery and development tool capable of providing essential and quantitative molecular pharmacodynamic data based on 25,000 phosphorylation sites in a single assay. The information obtained by our solution will go far beyond existing antibody-based detection systems and overcome their limits in terms of specificity and comprehensiveness without compromising sensitivity and robustness. DrugPhosphoProfiler will thus increase the success rate of pre-clinical drug discovery as well as clinical trials and eventually lead to more effective treatment of disease. Through this project (estimated ROI of 6), we at OmicScouts (SME, G