RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Regulated secretion and role of urinary nanovesicles' to be submitted under Horizon 2020.

assistant: **Abstract**

Extracellular nanovesicles called “exosomes” are small membrane-bound vesicles that are secreted by a variety of cell types. Exosomes contain various molecular constituents of their cell of origin, incl. proteins and genetic materials. The exosome release pathway contributes towards protein secretion, antigen presentation and pathogen transfer and roles of exosomes in intercellular communications and transfer of materials have been studied in immunology, neurobiology, stem cell and tumor biology. Exosomes are also released into the urine, although their role in urine is unclear and provides the basis of this fellowship. To gain novel information about urinary exosomes, a transdisciplinary approach is required. I will use my current knowledge of qualitative and quantitative proteomics combined with extensive bioinformatics to study urinary and renal exosomes and their ‘cargo’ secreted under normal and pathophysiological conditions. I will combine this information with new ideas and techniques I will learn in my host laboratory to examine rates of exosome secretion and to assess whether exosomes have the capacity to inhibit the growth of bacteria. Methodologies in this fellowship include techniques which I have extensive experience of e.g. large scale proteomic profiling, and novel techniques that I will learn in the host lab to enhance my research portfolio and future career prospects, including cell biological and microbiological techniques and experience in collecting/using samples from patients. The scientific goals of the project are to investigate the underlying mechanisms for regulated exosome secretion and the role of exosomes in innate immunity. As exosomes are secreted from multiple cell types, this study will have major implications for a variety of biology dis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Significant or trivial: Fungi in Polar Ecosystems' (F-Pole).

assistant: **Concept**

Fungi are major components of the Earth's biosphere, playing a pivotal role as decomposers and recyclers of nutrients across different environments. However, fungal diversity and function in marine environments has been poorly studied, leading to a biased picture of fungal distribution. Latest studies indicated a distinct marine fungal diversity, including chytrids which can affect algae and zooplankton communities because of their parasitic lifestyle or function as food source. The project intends to investigate the importance of marine fungi in polar-regions, environments that promote the occurrence of endemism and thus the detection of novel species. WP1 aims to study marine fungal diversity and distribution and to provide novel and unique information on the influence of environmental variables on the biodiversity of fungi in these important and changing environments. Two hypotheses will be tested in this work package: firstly, are the fungi identified representative of 'bona-fide' marine lineages and not land-derived origin? Secondly, do fungi represent a higher diversity in marine polar waters compared to temperate and tropical waters? WP2 aims to elucidate the genes transcribed by polar fungi in these atypical and cold environments. This work will allow me to understand the biological characteristics of these fungi that underpin their diversity and distribution profiles by using comparative meta-transcriptomic analysis of environments rich in polar chytrid lineages. Once both work packages are brought together they will help to fill the gap in our understanding of the marine environment, providing important information on ecology of marine communities. Polar environments are undergoing unprecedented changes, it is therefore crucial to understand important componen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Genomics of the Botrytis cinerea grapevine interaction'.

assistant: **Innovation**

The training objective of the proposed research is to complete the researcher’s existing knowledge in mycology and molecular biology by an interdisciplinary experience in infection physiology, genomics and modern bioinformatics, thus providing a boost for her career development and independence. The research objective of the project is to investigate fungal pathogenicity at the genomic level. The chosen model is the interaction between grapevine and grey mould because wine production plays an important role in European agriculture (several billion € market value), because grey mould is a major pathogen of this crop and because the high amounts of fungicides used to control the pathogen each year increase production cost and raise environmental issues. The genomes of the fungus B. cinerea and the plant V. vinifera have recently been sequenced, and the new available genomic tools should, for the first time, allow the drawing of an integrated view of the interaction between the pathogen and its host, and the deciphering of the largely unknown molecular mechanisms that support the fungus attack or the plant defence. As part of an effort to fully characterise the infection process, the aims of this project are 1) to identify the major fungal molecular players at work in the interaction between grapevine and B. cinerea and 2) the validation of these players in search of new targets for fungicides. Transcriptomic analyses of the infection will be performed using micro arrays, and a global profiling of the fungal genes will be obtained. Gene replacement will then be used to disrupt cellular functions highlighted by the genomics data, and analysis of the mutants will reveal the genes important in the infection process. This project should help develop control strategies that are
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Integrating Non-Abelianity in Euclidean lattices: From Cayley lattices to Circuit simulation' (CayLat).

assistant: **Concept**

Most condensed matter physics happens on lattices with commuting translations—move right then up equals up then right. But hyperbolic lattices break this: translations become non-Abelian (NAB) or non-commutative, bringing remarkable physics—novel phases from single particle to many-body, superior quantum error correction, enhanced AI memory. Problem: hyperbolic lattices need exponentially growing connections, impractical to scale.I propose Cayley lattices (CayLats): NAB translations in flat space without curvature. The trick is algebraic—replace each lattice site with n internal states corresponding to n group elements of Zn. The Hamiltonian splits into Abelian and NAB sectors in the same flat lattice. For Z2 CayLats, I've shown electric fields at different angles produce completely different spectra in NAB vs Abelian sectors—direct proof of non-commutativity without curved space.Higher Zn gets fascinating. Z3 and Z4 CayLats may break time-reversal in NAB sectors while preserving it in Abelian ones—impossible in regular lattices. Topological phases scale with my ""NABity parameter"" measuring translation non-commutativity. Larger n→more NABity→richer physics.Theory needs experiments. I construct CayLats using electrical circuits simulation—inductors/capacitors mimicking tight-binding models. Circuit Laplacian becomes Hamiltonian, impedances reveal spectra. LTSpice simulations show path-dependent impedances, NAB-specific boundary modes—ready for ETH's electronics lab. Impact: In quantum systems, photons between qubits get path-dependent coupling without external control. Same distance, different interaction based on route—fundamentally new. With supervisors Bzdušek (topological band theory) and Neupert (many-body physics) at UZH, we will showcase NAB physics does not nee
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Promoting Creativeness in Augmented Media Services'.

assistant: **Objectives**

The demand for new media content where videos are augmented with computer generated graphics grows rapidly driven by the enormous amount of online videos and the advent of new eye-wear and mobile devices. In a typical video content production workflow, expensive human resources are allocated for the creation of high quality and realism videos. The high cost of content production remains mostly with SMEs representing 85% of the creative industry sector. The use of automatic video analysis can significantly optimize the existing production workflows and cut the cost. Yet the video analytics market dominated by SMEs is highly fragmented too: Video analytics is only available at high prices and locked to vendors. This limits the interoperability and results into overall market inefficiency. This proposal offers the solution to this problem by bringing the developers of video analytics and their users from the content creating industry together on a shared video analytics WEB repository with innovative services for selecting, testing and soliciting all kinds of video analytics solutions. The repository allows the users to choose the solution with the utmost transparency: The user can directly test all available solutions in the repository with own videos. If the content creator cannot find a suitable video analytics from the wide range available, he can solicit a newly developed video analytics solution, which is tailor-made to his requirements. The objectives of this proposal are i) establish the WEB repository; ii) define core video analytics applications relevant for content creators; iii) collect a large number of relevant video analytics applications in the WEB repository; iv) customise WEB repository services to the needs of content creators; v) demonstrate added value
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'NANOTECHNOLOGY-ENABLED DETECTION OF CLINICALLY RELEVANT ANTIBODIES FOR EARLY CANCER DIAGNOSIS AND IMMUNOTHERAPY MONITORING', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Nano-ImmunoEra is a research and innovation staff exchange network aiming at the development of innovative biosensors and diagnostic tools for the detection of clinically relevant antibodies. Nano-ImmunoEra will form the next generation of clinically-oriented analytical scientists capable of delivering innovative solutions that will improve the lives of patients, reduce the cost of healthcare and position Europe as a leader in biomedical devices. Since standard laboratory-based methodologies and disposable tests present several analytical limitations, we have selected antibodies as molecular targets of this project because their rapid, sensitive and specific detection in bodily fluids still represent a significant diagnostic challenge. To deliver these goals, we have assembled a highly inter- and multidisciplinary and multicultural team of European as well as strategic non-EU Countries (USA, Switzerland and South Africa) through the collaboration among 7 academic institutions and 2 non-academic partners to enable ultimate impact to the healthcare. The expertise of different and multidisciplinary research teams, comprised of PhD and Postdoctoral as well as experienced researchers from Universities and companies, will endow Nano-ImmunoEra with a strong intersectoral dimension, which is of high importance for a broad and effective impact of the project. In addition, this program involves key participation of junior researchers with exceptional scientific backgrounds and accomplishments, and will provide strong support for the development of their careers. The transfer of knowledge and related training activities aim to provide scientists achieving specific competences in the field of materials sciences, nanotechnology, molecular biology and biosensors.


**Keywords:** Elec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Stochastic partial differential equations with reflection and applications' (1998-2002), addressing dissemination and exploitation.

assistant: **Impact**

In 1992, D. Nualart and E. Pardoux introduced a Stochastic Partial Differential Equation with Reflection. In our PhD Thesis, we gave a connection between this equation and the Theory of Dirichlet Processes. This connection opens a number of problems. The Nualart-Pardoux (NP) equation admits an interpretation as an infinite-dimensional Skorokhod problem; the related geometrical objects, i.e. the state space, the boundary, the boundary measure and the normal vector field, are dictated by the unique invariant measure of the solution of the NP equation. The Local Time of the solution at the boundary, uniquely determined by the boundary measure, appears as a natural time scale for the solution. A deep understanding of the properties and the structure of this Local Time should allow in particular to obtain strong information about the geometrical structure of the contact set, i.e. the subset of space-time where the solution hits 0. The NP equation is an explicit example of a stochastic system with infinitely many degrees of freedom and with a reflecting boundary: a general theory of such systems is still in its infancy. Moreover, the interest in a fine analysis of the NP equation is motivated by the possibility of modeling several interesting phenomena from Physics, Biology and Mathematical Finance: e.g. a recent result of T. Funaki and S. Olla, connects the NP equation with the fluctuations around the hydro dynamical limit of an Interacting Particle System near a wall.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'MS-LAB: Manuscript Lives Across the United Kingdom of Great Britain and Ireland, 1860-1920.' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Manuscript (MS) magazines were handwritten magazines that were created for private consumption by groups of people whose contributions to the magazine made up its contents. Though research on manuscript magazines is scarce, and archival examples are scattered, they were an important part of self-made cultures circa 1860-1920. A rise in literacy, and Golden Ages of journalism, periodical literature and children's literature contributed to their popularity. Though they were often started in the domestic space, and spoke to highly localised concerns, they were circulated and had a wide readership, much like social media of today. This project, ‘MS-LAB: Manuscript Lives Across the United Kingdom of Great Britain and Ireland, 1860-1920’ will interrogate the place of MS magazines in family life and the development of literary cultivation across the four nations of the United Kingdom during the period in question. Through new archival research conducted in the four nations, and the design of a new methodology for comprehending the form and content of MS magazines, this project will produce new knowledge on this underexamined facet of shared cultural heritage. A dedicated web project hosting digitised surrogates of these manuscripts will share findings on these manuscripts with a wide public audience. During a non-academic placement with the Department of Archives and Manuscripts Collections in the National Library of Scotland, the researcher will share insights with colleagues working in the heritage industry who are typically the custodians of these unique manuscripts. The project's outcomes will pave the way for further work on this unique form in mainland Europe, as the web project and multimodal methodology can be applied to MS magazines found across other European collect
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Generation of Nonclassical States of Light in Silicon Nitride Photonics by Second-Order Nonlinearity' (GLINT).

assistant: **Concept**

Harnessing the quantum properties of light on-chip is the ultimate aim of Integrated Quantum Photonics, bearing the promise of novel quantum technology functionalities to the microscale. A critical step in this process is the generation of quantum light, typically achieved through nonlinear processes such as spontaneous parametric down-conversion (SPDC) in second-order (χ(2)) nonlinear media or spontaneous four-wave mixing (SFWM), through the third-order (χ(3))  response. While the silicon nitride (SiN) integrated photonics platform has proven extremely reliable, low-loss, and compatible with large scale fabrication, its centrosymmetric nature of SiN prevents χ(2) interactions, hindering the implementation of low-noise, highly efficient SPDC-based sources. Lithium Niobate and III-V materials are valid alternatives, but they lack the technological maturity provided by the CMOS fabrication process. Recent research has shown that the coherent photogalvanic effect can endow SiN with a χ(2) response, a photoinduced nonlinearity that automatically satisfies the quasi-phase matching condition, enabling highly efficient frequency conversion. Such “all-optical poling” technique has proven suitable to enable a wide range of functionalities based on χ(2) interactions. The purpose of GLINT is to investigate the potential of all-optical poling in SiN for the generation of quantum light via χ(2) processes. The project will specifically focus on the study of SiN microring-resonator-based SPDC sources, owing to their capability to enhance the efficiency of spontaneous processes and to generate, thanks to their peculiar spectral response, narrow-band states. This will be achieved by i) theoretically modelling a resonator-based SPDC source ii) realizing a chip-scale prototype using comme
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'The evolutionary ecology of individual variation in cognitive performance'.

assistant: **Concept**

This proposal takes the disciplines of cognitive and evolutionary biology into a natural setting on an unprecedented scale to explore a variety of causes and consequences of individual variation in cognitive ability.The study system is a series of great tit (bird) sub-populations across habitat fragments of very different quality, consisting of conifer plantation and natural broad-leaf woodland. Great tits are year-round residents that use a wide range of patchily distributed food types, suggesting an important role for different cognitive processes. They are readily tagged and use nest boxes freely, making them easy to monitor remotely.In the first work package, the aim is to examine social and individual causes of variation in different indicators of cognitive ability (e.g. associative learning ability), to determine whether these differences are linked to life history variation, and if so, to ask if this necessarily leads to selection for higher cognitive performance, or instead whether cognitive ability also comes with costs.Natural selection rarely acts on traits in isolation and is dependent on current conditions. Thus the work package will also explore whether observed patterns are moderated by other functionally relevant phenotypic variation (personality and bill morphology) or are dependent on habitat quality. Ultimately the aim will be to combine estimates of heritability generated from pedigree animal models with selection to measure the predicted micro-evolutionary responses.In the second work package, the aim is to explore the functional mechanisms underlying links between cognitive ability and life history variation, testing whether cognitive variation is linked to: i) space use in the natural environment, ii) foraging decisions and diet profiles, and iii)