RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Valorisation of mushroom agrowastes to obtain high value products' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The project aims at the valorization of agricultural residues coming from mushroom (Agaricus Bisporus) farming residues as a case to set up new cascading possibilities using innovative procedures to extract high value bio-based additives (antioxidants, antimicrobials, proteins), convert lipids into bioplasticizers and polysaccharides (glucans and fermentable sugars) into biopolymers using remaining side streams in substrates to close the agricultural cycle by composting and/or biogas synthesis. The funguschain project will demonstrate its industrial viability by building a new biorefinery that will use cost-effective extraction technologies (MAE and HWPE) revalorizing more than 65% of waste into valuable additives.These additives will be incorporated into high added value products and industrially validated towards 3 key value chains in the European economy (food, cleaning and plastic sectors). Industrial lines from end-users will be modified and adapted to the developed products. These products are: food supplements for elderlies, cleaning products, novel biobased thermoplastic masterbatches, bioplasticizers and industrial film products (thin bags and gloves <15 microns, partially recycled thick bags >50 microns and mulching).A business strategy to valorise the products in a collaborative manner will be designed, leading to safe, sustainable, economically viable and attractive products acceptable to consumers. Partners will ensure that products meet legal and market requirements. The project will forge and propel industries growing within the frame of the European bioeconomy, boosting the community network.The consortium involves 16 partners (4 RTDs, 4 Large industry and 8 SMEs) accounting with 5 BBI full members and 3 associate members. Funguschain project has a durat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Combustion Models for Industrial Applications' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Combustion processes are an essential component of energy conversion and their accurate modeling is required if the objectives of reduction of fuel consumption and emissions are to be realized. Meeting these requirements will involve a substantial effort, in particular towards the development and availability of accurate and reliable simulation tools for reactive flows and more experimental data.  In the COMBINA project, collaboration between a CFD software developing SME, which is coordinating this project, four major research groups on combustion and an SME specialized in experimental analysis of combustors is established.  The research partners are originating from Belgium, Netherlands, France, Germany and Turkey. The partners will share and contribute with complementary expertise on the modeling of premixed, partially premixed and spray combustion including RANS and LES modeling and the generation of new experimental results for their validation.  An industrial observer group (IOG) of representatives from the gas turbine manufacturing industry will advice the consortium on longer term industrial objectives and provide additional test cases.  The current COMBINA project opens new pathways across the different sectors. The coordinating SME-1 is having the most recent numerical combustion models integrated in its software system towards the demands of end users in the manufacturing industry. SME-2 will benefit from intensive exchanges and transfers on experimental and numerical techniques and tools. The university partners will gain access to industrially relevant testcases from SME-2 and the IOG and to an industrial CFD software environment for testing advanced models on real-life applications that so far have only been applied with academic codes on simplified config
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Cutting system for ornamental stone blocks' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

The main aim of the project is to optimise the cutting system of ornamental stone blocks coming from the quarry. Nowadays during this process the quality of waste generated is important, due to the big size of the cutting iron strap. The project also seeks to avoid the excessive idle times produced during the change and transportation of the cut blocks and the preparatory of the next one by a new development and design of the gun-saws. The present project is focused to solve the problems, both industrial and environmental aspects, reducing the cutting width (the losses of marble material would strongly decrease) achieving an important economic saving and also minimizing the wastes of material and improving the productivity of the cutting process.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Sustainable management of Mediterranean coastal fresh and transitional water bodies: a socio-economic and environmental analysis of changes and trends to enhance and sustain stakeholders benefits' to be submitted under Sixth Framework.

assistant: **Abstract**

Management decisions of fresh water resource are generally driven by the urgency of recent changes in the human (globalisation) and natural (climatic changes) contexts. However, the local context, which is most sensitive to human impact, is often neglected , resulting in conflict. The project aims at encouraging the rational and sustainable use of fresh and transitional water resources within the Mediterranean coastal area, which experiences freshwater scarcity, through participatory approaches. Fresh water bodies in coastal areas, essentially where large demographic concentrations occur, are particularly at risk of negative impacts, risks and threats, both natural and anthropogenic. Water management measures may affect ecosystem viability and sustainable res ource production, which in turn may have a negative influence on Mediterranean human populations, sustained economic growth and development. A number of significant case studies throughout the Mediterranean have been selected for assessment and subsequent analysis. The socio-cultural and environmental contexts will be considered holistically, through an ecosystem approach, to avoid the risk of emphasising specific features or underestimating the needs of fragile components within the system. The assessment of impacts and indicators thereof will result in the development of alternative case-study scenarios, based upon sustainable management strategies, for the potential use by stakeholders. Tangibly, these management plans may subsequently be utilised by stak eholders within the study site environs, as also in the wider context of the Mediterranean, whereby the project case-studies may be extrapolated to other scenarios within the Basin. The specific role of women as end-users of water will be a main focus and speci
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Molecular anatomy of the mouse embryo' (1994-1998).

assistant: **Concept**

Research objectives and content In my proposed project I plan to use a novel approach developed in Bernhard Herrmann's laboratory to isolate and describe expression patterns of a large majority of genes active in midgestation mouse embryos. This approach is based on using cDNA riboprobes derived from characterized stage specific cDNA libraries for multiple in situ hybridizations of whole-mount embryos. Using a large scale application of this technique I will generate expression patterns of up to two thousand different genes in 9.5 - 12.5 day mouse embryos. From the projected number of expression patterns I will choose to further characterize genes likely to interact downstream of Brachyury (T) in mesoderm and notochord by knock out" mutagenesis and functional analysis. In summary this project should result in an expression catalogue of 2000 different genes of 9.5 -12.5 day embryos and should provide new insights towards understanding of mesoderm formation but also in a multitude of new molecular markers of mouse embryo. Training content (objective, benefit and expected impact) Personally this training grant would facilitate to do this project and make it possible for me to learn many new techniques and establish myself in the fields of developmental biology. Links with industry / industrial relevance (22) In a pilot project of the in situ screen in Bernhard Herrmann's laboratory about 10 to 15 new genes have been identified specifically expressed in blood cells and/or cells of the blood endothel. It is expected that a similar number of new genes specific for these tissues will be discovered as a sideproduct in my proposed project. These genes are clearly of industrial relevance in sight of medical research of blood endothel and hematopoiesis. "
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Towards a Dynamical Understanding of Allostery', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Allostery is a fundamental concept Nature uses to regulate the affinity of a certain substrate to an active site of a protein by binding a ligand to a distant allosteric site. We will design experimental tools to gain an atomistic understanding of the conformational transitions that give rise to allostery. We will approach the problem from two distinctively different directions. First, we will initiate conformational transitions of proteins that per se are not photoswitchable, by cross-linking two sites of an allosteric protein with a photo-switchable azobenzene-moiety to initiate a conformational transition similar to ligand binding. We will use ultrafast infrared spectroscopy to time-resolve the conformational transition. Second, we will experimentally verify a frequently expressed hypothesis that allosteric and active site communicate by exchange of vibrational energy. To that end, we will design a versatile approach that allows us to locally deposit vibrational energy at essentially any site in a protein (e.g. through pumping of an optical chromophore that undergoes ultrafast internal conversion), and to detect its appearance at any other site by using vibrational transitions as local thermometers. Thereby, we will map out a network of connectivity in a given protein. Both approaches will applied both to one and the same protein family. One concrete example are PDZ domains, which are among the smallest allosteric proteins, and for which the connection between allostery and vibrational energy flow has been made explicit, based on computer simulations. We will eventually test this hypothesis experimentally, and provide the foundation for a description of allostery that is on an equal footing as our current understanding of protein folding.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Fundamental Fields and Compact Objects: new opportunities' (NewFunFiCO) targeting Horizon Europe.

assistant: **Abstract**

The celebrated detection of gravitational waves (GWs), the first observation of horizon scale structure of a black hole (BH) together with the developments in the field of numerical relativity, are allowing access to extreme (strong and dynamical) gravity configurations, both observationally and theoretically, making our time a golden epoch for studying extreme gravitational systems.In parallel, families of exotic but theoretically sound models of BHs and horizonless compact objects in the presence of new fundamental fields, or alternative theories of gravity have been constructed, to a large extent numerically. These can be submitted to computational experiments, to test their dynamics, and compared against observations, to address the issue of degeneracy in the theoretical interpretations of strong gravity data or even detect putative better fits to the data. At the meeting point between these two developments lies the promise of new fundamental physics, a deeper understanding of BHs and neutron stars, unveling the nature of dark matter and dark energy. Delivering on this promise requires a synergetic endeavour that must bring together different groups and competences. This project creates a multi-connected team with different and complementary scientific expertises - on BHs, neutron stars and exotic compact objects -, their phenomenology - GWs, lensing and astrophysical environments - and the techniques necessary to extract the latter from the former for comparison with observations, including constructing and evolving solutions of non-standard compact objects with numerical methods, building GW libraries, lensing images and performing data/Bayesian analysis and parameter estimation. The team includes members of the LIGO-Virgo-Kagra and Event Horizon Telescope collab
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'TRILLIO, a porTable pRescription assistant Improving heaLth of Europeans citizens by increasing therapeutic adherence in eLderly people and in patIents affected by chrOnic diseases'.

assistant: **Objectives**

Therapeutic adherence is defined as “the extent to which a person’s behaviour – taking medication, following a diet, and/or executing lifestyle changes, corresponds with agreed recommendations from a health care provider”.  It is estimated that each year the poor adherence to medical treatments in Europe causes about 200,000 deaths and burdens on health expenditure up to 80 billion euro a year (AIFA source). TRILLIO is a therapeutic adherence device really similar to an “alarm clock”, thus really familiar for elderly. The TRILLIO device is provided with an app that optimizes the connections among various players and organizations who share a common goal: make sure a patient follows his or her pharmaceutical treatment plan. When it's time to take a drug, TRILLIO alerts the user with a sound and a visual alarm, while showing all the relevant information on its 2.7"" e-paper display. If the user doesn't press the button on the device to turn off the alarm within ten minutes, TRILLIO automatically sends a notification to any family member connected to the system. TRILLIO has been already tested in Italy and received serval endorsement by organisations in Italy and abroad.We are a targeting and overall population composed by 150.000.000 European that are suffering from Chronic diseases, 50% of them have difficulties in following a therapy: we are addressing 0,2% of this market and we are aiming at selling 112.000 devices by 2023, that will generate 17M€ turnover. The Feasibility study will have the purpose to support us in completing the market analysis, in launching a small pilot (i.e. 500/1.000 users), in identifying suitable partners in Europe for wide demo site (i.e.  hospitals) and in identifying the right partners for distributing TRILLIO in Europe. TRILLIO is brought
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Ultrasonic technology for bioprocess enhancement' (USONIPRO).

assistant: **Innovation**

BBH Biotech Polska was created with a thought of using sound waves to enhance and control microbial metabolism. After 3 years of research the team created a company and focused on using sound waves as a stimulating factor in enhancing alcohol production. From the day the company was established, its strategy and long term aim was to adjust its technology of sonic fermentation enhancement to recombinant proteins, fine chemicals and drug production.The biggest problem in recombinant protein production using microbial expression systems is that a part of produced proteins are being stuck in the periplasmic space while being transported outside the cell. Treating such loaded microorganisms with adjusted sound waves can destabilize the inner membrane and outer wall in order to reclaim those proteins. This innovative procedure allows the molecules to escape the periplasmic space to the cultivation medium without destroying the cell, which was so far the biggest obstacle.Currently there are only few available methods that solve this problem, and BBH Biotech Polska is the only company developing such solution in a form of technology which is highly effective and after Phase 1 – ready to enter the market.Users of this technology will be companies producing human and animal pharmaceutical proteins with microbial expression systems. Such pharmaceuticals are expensive products, which means that an increase in production even by little, e.g. 3 – 7%, is enough to give that company an annual increase in revenue form 30 even up to 80 million dollarsOur technology increases production yield from a single cultivation from 30% to 90%, depending on the protein and the expression system. Such boost to productivity will not only hasten the growth of the market, but also decrease the cost of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'NEGOTIATING SOVEREIGNTY: CHALLENGES OF SECULARISM AND NATION BUILDING IN CENTRAL EASTERN EUROPE SINCE 1780' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Why does the modern state, with its claim to sovereignty, care so much about secularization and (re)sacralization? In order to address this question, the project examines the (pre)history of the conflict-ridden relationship between transnational institutions and the modern state and also the players who stood at the point of intersection of the two by analysing the shifts in relations between the state and one of the oldest transnational institutions in the world, the Catholic Church.The project examines the conflicts between church and state and the various processes involved in attempts to address these conflicts first and foremost by studying the history of the oaths of loyalty that the (chief) pastors of the Catholic Church were obliged to take and the tensions which arose because of these conflicts in the Habsburg Monarchy and its successor states between 1780 and 1990. Oaths of loyalty to the state bear the marks of the changing relationships between the nation state and the transnational Catholic Church and were generated directly through the negotiations of sovereignty among these actors. The project will offer a comprehensive interpretation of oaths of loyalty in the context of Josephinism, nation building, and communism and their transformations in the context of the shifting relationships of the national, state, and transnational loyalties. Thus, it will provide much needed tools for a longue durée and comparative analysis of state-church relations in Central Eastern Europe. It will also discuss patterns of continuity and discontinuity between the church policy of different regimes, the common and different features of the role of Catholicism in nation building, and the related change of function of the Catholic hierarchy among the peoples of the Habsburg Mon
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'QuiX Quantum Universal Quantum Processor' in the context of a Horizon Europe call.

assistant: **Objectives**

Quantum computing is a technological revolution that will unleash the most dramatic changes in our everyday lives since the invention of the internet. Quantum computing has the power to impact every major global industry, from pharmaceutical research to climate action and personalized healthcare to space travel. However, today’s quantum technologies still suffer several drawbacks. They require cumbersome and rigid hardware, such as cooling to almost absolute zero, and suffer from both noise and decoherence. QuiX Quantum is bringing to market the first scalable universal quantum processor based on our disruptive photonics innovation. For the first time, we will be offering a scalable, marketable universal quantum processor that can be adopted by companies, research institutes, and government organizations to change the world in which we live. We are seeking EIC support in the form of blended finance to bring our first universal quantum processor product to market as early as 2026.