RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Control of Extreme Events in Turbulent Flows with Scientific Machine Learning' under Horizon Europe.

assistant: **Concept**

Climate change and the race to decarbonise our society is making extreme events in fluids more prevalent. These are rare events where the flow suddenly takes extreme states far from its normal state. These can be found in any flow systems, such as in the atmosphere with atmospheric blocking causing extreme heatwaves, or in our oceans with rogue waves (waves of extreme heights) capable of capsizing boats, or in engineering flows in hydrogen-based clean combustors with flashback events where the flame suddenly moves back into the injection system.Currently, we cannot accurately predict such extreme events due to several roadblocks. First, the chaotic nature of these turbulent flows makes them hard to predict: any infinitesimal perturbation leads to drastically different evolutions (the butterfly effect). Second, extreme events originate from complex nonlinear interactions which are very different for systems with different physical mechanisms. This makes any past development difficult to generalize across different flow systems. Third, we have very limited observations of such events.To revolutionize how we tackle extreme events, the CONTEXT project will create a cutting-edge scientific machine learning framework that blends deep learning with physics-based techniques. CONTEXT’s framework will provide the means to (i) identify precursors and mechanisms of extreme events, (ii) forecast the flow evolution before and during extreme events and (iii) control the flows to prevent extreme events. CONTEXT’s framework will be able to handle diverse and disparate physics, with this being demonstrated across different flows of increasing complexity and with different physics, culminating in a demonstration of the practical impact of the framework on the engineering-relevant multiphy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'ANTHEM: A Novel Tolerogenic vaccine for the treatment of antibodies in HaEMophilia'.

assistant: **Objectives**

This project will develop and validate IN-3012, a novel tolerogenic vaccine that utilizes a person’s own cells to treat neutralizing antibodies (NA) in Haemophilia A patients who have failed immune tolerance induction (ITI). Haemophilia A patients are given the blood clotting protein, factor VIII as standard of care. However, a serious consequence  is the development of NA towards factor VIII leading to therapy resistance. This leads to crippling arthropathy, other morbidities and high mortality. ITI is the most used treatment of this condition but 35% of patients do not respond and are in a vulnerable situation.Haematologists and KOLs emphasise the pressing need for safe and effective technologies to overcome NA in Haemophilia A, which is not possible today. The estimated mean annual cost of a Haemophilia patient in Europe is over EUR 117,000 EUR with the mean lifetime cost reaching EUR 7.8 million. This is substantially higher in patients who have failed ITI. Therefore, while this condition has low prevalence, it exerts heavy burden on healthcare budgets and is thus a top EU health policy priority. Idogen’s technology platform allows cells from the patient’s blood to be reprogrammed outside the body to dendritic cells with the capacity to specifically counteract adverse immune reactions. The reprogrammed cells are transferred back to the patient. IN-3012 uses this mechanism to create tolerance to factor VIII. The research performed to date strongly supports the vaccine’s potential to eradicate NA. The proposed project will bring IN-3012 through a Phase I/II clinical trial in humans. The safety and preliminary efficacy data will constitute the basis for further clinical development and commercialisation of the product. Idogen’s strategic focus lies in establishing IN-3
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Evolution of reproductive barriers and its implications for adaptive speciation' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Perhaps the most basic question about the process of speciation is whether or not it is an adaptive progress. Recent studies suggest that natural selection and adaptation may play a more significant role in the early stages of divergence and the evolution of reproductive isolation than previously thought. This ‘adaptive speciation’ may be particularly common where there is partial spatial separation between habitats, such as on the steep environmental gradients that characterize sea-shore habitats. Species living in these habitats are, therefore, excellent models for the study of adaptation and its contribution to speciation. Novel approaches based on genomic tools now make the genetic basis of adaptation and speciation more accessible than ever before. The overall goal of the proposed application is to increase our understanding of adaptive speciation. My model system will be the rocky shore gastropod Littorina saxatilis. This powerful model shows independent but similar responses to habitat gradients in different parts of Europe, with evidence of progression towards speciation. I will combine studies of morphological variation, using the latest methods of geometric analysis, with the population genomics approach, using AFLP markers, to dissect the genetic basis of adaptation and the role of morphological adaptation in the overall divergence between snail morphotypes. Furthermore, I will examine plastic responses to the environmental gradient and determine their contribution to adaptation. This project will provide me with a much enhanced suite of skills, including new laboratory and analytical skills in molecular ecology and population ge
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Information, Markets, and the Macroeconomy' (INFOMAK), addressing dissemination and exploitation.

assistant: **Impact**

Financial markets play an essential role in allocating an economy’s resources to their most productive use, fostering investment, employment, innovation, and growth. While there is substantial evidence that financial markets are plagued with information asymmetries and its perils, we do not have a good understanding of what economic conditions may foster such information asymmetries, or how they interact with aggregate investment decisions, liquidity in asset markets, or economic fluctuations. In order to fill this gap, the goal of this proposal is twofold: The first component focuses on understanding the drivers of information asymmetries. To do this, first, I will develop novel microeconomic frameworks where the degree of information asymmetries and the quality of assets is endogenously determined by agents’ decisions to produce complex financial products (project 1) or to trade in opaque markets (project 2). Second, I will construct a novel dataset of financial products’ attributes to explore the drivers of asset quality and complexity in the data and to test the predictions of my theoretical frameworks. The second component explores how information asymmetries, through their effect on financial markets, interact with aggregate outcomes, such as market liquidity and investment. To do this, I will develop novel macroeconomic frameworks where I embed my insights on complexity (project 4), and opacity and asset quality (project 5) into dynamic, general equilibrium settings.


**Keywords:** Information asymmetries, economic fluctuations, complexity, opacity, learning, regulation, credit cycles.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'South Slavic CLItics in language Contact contexts'.

assistant: **Innovation**

The project investigates the effect of language contact on the structural make up of clitics through the analysis of their use and function in three South Slavic contact varieties: Molise Croatian (MC), Burgenland Croatian (BC) and Torlak (TK). Although clitics have been extensively examined in standard(-ized) Slavic languages, very little attention has been paid to marginalized and/or endangered varieties. Besides the language preservation and documentation effect, the study aims to provide an insight in the layering of complexity in the syntactic structure of clitics by examining their inventories, the structural layers truncated in the simplification triggered by contact as well as those interacting with the structures of the other contact variety, specifics of the clitic cluster and the presence or absence of clitic doubling and clitic climbing. The chosen varieties constitute a minimal triple, since 1) MC has had a very extended contact with Italian and Italo-Romance varieties, having a fairly rich clitic system, 2) BC has been in contact with Austrian German, displaying very scarce cliticization phenomena and 3) TK has been in contact with Serbian Standard, Macedonian and Bulgarian, all with very rich clitic systems. Empirically, the project combines fieldwork in terms of a sociolinguistic questionnaire and elicitation tasks in the three areas with a corpus-based study. The latter extends an ongoing study on Torlak to further marginalized South Slavic varieties in order to provide a wider perspective onto contact-related issues. The data is treated both quantitatively and qualitatively. The results of this investigation will therefore not only fill the gap in the empirical description of the use of clitics in understudied varieties and types of contact, but they w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Recurrent disease in the liver transplant: window to identify and stop gut signals driving autoimmunity' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Autoimmune disease is an increasing health concern. These diseases are strongly associated with altered gut microbiome. When immunosuppression fails there is little to offer in terms of therapy. In this project, I hypothesize that gut signals (microbial factors from the intestine) unaffected by immunosuppression are key drivers of autoimmune diseases. I propose to use recurrent autoimmune disease after organ transplantation as a human disease model to identify and stop these gut signals, providing a novel approach to close the gap between basic microbiome research and patient care in autoimmune diseases.To identify autoimmunity-related gut signals, I will use patients with primary sclerosing cholangitis (PSC), an inflammatory disease of the bile ducts. PSC is a common indication for liver transplantation, but after transplantation there is high risk of recurrent PSC (rPSC). I recently showed that the PSC gut microbiome has low diversity and identified microbial metabolites associated with severe PSC. Preliminary data show that the post-transplant gut is even less diverse, suggesting that microbial factors drive autoimmunity. In this project I will identify gut signals by in-depth investigation of gut bacterial genes and circulating metabolites in the blood. The outcome will be diagnostic and prognostic markers overlapping in PSC and rPSC, defined by changes in gut bacterial genes and concentrations of bacterial metabolites in the blood. Next, I will investigate if common drugs or interventions influence the identified autoimmunity-related gut signals. By generating a library of interventions influencing the gut microbiome it will be possible to select promising candidates for pilot treatment trials after liver transplantation. The outcome of StopAutoimmunity will be gut
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Upgrading wastewater treatment systems by self-adaptive automation systems'.

assistant: **Objectives**

Improving the efficiency of existing wastewater treatment plants at low or moderate costs is central task of European environmental industry. Objective of the project is the introduction of new innovative technologies into the wastewater industry: Low-cost microelectronic silicon sensors in combination with self adaptive software systems like Neural Networks are able to improve dramatically the efficiency of wastewater treatment plants by optimal control strategies. The new technology will be well accepted by the end-users because the control algorithms are self-learning and self-optimising. The partners expect for the wastewater works integrated in this project an average decrease in energy consumption of about 10% and a decrease of the peak concentrations of typical water contamination like NO_3-N and NH_4-N in the outlet of about 20%.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'REDUCING ENVIRONMENTAL RISK THROUGH STRENGTHENING OF MANAGEMENT OF HAZARDOUS WASTE FROM INDUSTRIAL, AGRICULTURAL AND MILITARY ACTIVITIES IN THE WIDER EUROPE' to be submitted under Sixth Framework.

assistant: **Abstract**

Risks related to hazardous waste are among the most important threats for populations at large. Moreover, strategies, policies and legislation lead to diversity of legal frameworks for their management in the Wider Europe. The main goal of the project is t o reduce environmental risk through the provision of a sound base for reinforcing legal mechanisms and instruments on international, national, regional and local levels for environmental risk management of hazardous waste resulting of industrial, agricultu ral and military activities and to develop a national focal point network leading to dissemination and adequate follow up. This project is intended as a concerted effort of existing Network representatives in France, Lithuania, Malta, FYROM,Serbia Monteneg ro, Armenia,Azerbaijan, Moldova, Ukraine and Russia to create a common basis towards a harmonised policy in the domain of hazardous waste management. Preliminary work has been done by this Network concerning a comparative analysis of the legislation on ri sk management in the partner countries. This project deals with the Specific Programs objectives in the way that the planned activities implement a multilateral coordination, associating three sub-regional areas of the Wider Europe. This cooperation is als o transversal and integrated, taking into account the interdependence of hazardous waste, across borders. Moreover, final recommendations should help future elaboration of regulating mechanisms and instruments harmonized at the Wider Europe level and devel opment of innovative R&D areas, to reduce the impacts downstream and also the production upstream. To achieve the objectives, the workplan leads up to undertake chronologically: compilation of databases of national legislation and standards on hazardou s wast
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Reconstructing Aristotle's philosophy of 'qua'' (QUA), addressing dissemination and exploitation.

assistant: **Impact**

Despite the centrality of the term 'qua' in Aristotle’s philosophy –  from the definition of ontology to his philosophy of mathematics – a comprehensive analysis of its role throughout the Aristotelian corpus remains absent in both European and global scholarship. The QUA Project addresses this critical gap by proposing a framework for a consistent understanding of the role of 'qua' in Aristotle’s philosophy. Unlike previous studies that have focused on the scientific uses of 'qua', where it contributes to defining specific sciences, QUA shifts the perspective to Aristotle’s Organon. Using a methodology that integrates philology, ancient Greek philosophy, and debates in contemporary metaphysics and philosophy of mathematics, QUA begins by reconstructing Aristotle’s theory of qualifications in the ""Sophistical Refutations"". It then demonstrates how the ""Analytics"" identifies 'qua' as a qualification of respect that specifies the category of predication. Finally, the project tests this framework by extending it beyond the Organon to address unresolved questions about the scientific uses of 'qua'. Supervised by leading Aristotelian scholars, Pierre-Marie Morel at Paris 1 Panthéon-Sorbonne and Rachel Barney at the University of Toronto during a secondment, the project benefits from their expertise and the support of their research units, GRAMATA and CSAMP. This international collaboration will significantly enhance the researcher’s academic profile, increase visibility, prepare future research projects, and improve competitiveness in the global job market. Furthermore, the outreach plan of the project addresses the construction of stereotypes and the potential of social critique inherent in 'qua predications' to foster a broader societal impact, extending the research’s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Cost-effective, high-efficient micro gas turbine for micro CHP applications' (ECOJET) under Seventh Framework.

assistant: **Objectives**

The EcoJet consortium – comprising a value chain of three European SME manufacturers of gas turbines and sub-systems, and suppliers of high-performance materials and coatings, together with an SME developer of CHP systems - aims to address a major market opportunity through the optimization and deployment of a proprietary 10 KWe radial micro gas turbine into an innovative system solution tailored for environmentally friendly micro CHP applications for the residential sector. EcoJet targets the development of an engine based on an innovative radial jet turbine with an integrated electric generator. The technology has a uniquely robust design and uses very few advanced components, which makes it inexpensive and simple to manufacture. As existing micro turbine technology, it is multi-fuel enabled; has a high power to weight ratio, low emissions; no vibration and noise. As a core novelty and differentiator, the EcoJet design simultaneously enables environmentally superior performance and cost-effective uptake of micro CHP compared to conventional reciprocating engine generators. The concept addresses S&T barriers related to materials selection and assessment and to the production of the monorotor and heat exchanger. The EcoJet solution has a range of unique selling propositions to a very large group of potential end-users – manufacturers of micro CHP systems and, ultimately, households – which, in addition to economic benefits, can contribute to the mitigation of environmental problems due to a reduction in energy consumption and emissions.The SME consortium has the capacity to produce and market the new solution, but lacks the financial resources as well as the research expertise that enable the required technological development. Therefore, the consortium has identified t