RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'An integrated hypothesis for cognitive and positive symptoms in schizophrenia' in the context of a Horizon 2020 call.

assistant: **Objectives**

An integrated hypothesis for cognitive and positive symptoms in schizophrenia:Schizophrenia is a complex developmental brain disorder with three main clusters of symptoms: (i) positive (psychosis, delusions and hallucinations), (ii) negative (reduced motivation and social withdrawal), and (iii) cognitive (memory and executive function deficits). For the last 50 years, the only effective treatment has consisted of antipsychotics targeting dopamine receptors. Yet, antipsychotics control mostly the positive symptoms and are largely ineffective at treating other deficits. It is frequently assumed that distinct pathophysiological mechanisms underlie different symptoms. Psychosis is associated with striatal hyperdopaminergia, probably due to abnormal activity of midbrain dopaminergic neurons. Yet cognitive deficits seem to arise from cortical excitation/inhibition unbalance. I propose to test, in a mice model, the hypothesis that striatal hyperdopaminergia results from dysfunctional cortical inhibition. If verified, this would suggest that normalizing cortical activity in schizophrenia might both restore cognitive function and prevent psychosis.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'COOPERATIVE WIDE AREA SERVICE ARCHITECTURE' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

CWASAR is aimed at boosting European industrial competitiveness via a secure communications infrastructure for an electronic market place. The focus will be on provision of services such as electronic fair advertising, identification of business partners, commercial transactions and modern document transfer facilities. The main concern is for a user-friendly electronic information and cooperation system as straightforward and trustworthy as communication by traditional mail and fax, with low initial investment costs for small and medium-sized enterprises.The goal of the project is to promote the competitiveness of European industry by providing a secure information and communication infrastructure for a European electronic market place. The key services provided are a continuous electronic fair for advertising, finding business partners, business transactions such as ordering, booking, contract negotiations as well as the transfer of documents such as text, hypertext, engineering data and multimedia documents.An extensive market analysis focused on the user group of small and medium sized enterprises (SMEs) has shown that the following properties are considered mandatory for a high acceptance of such a system: a small amount of investment, a rich set of participants, dependable services and modularity of the system.Our conclusions are twofold: First, an electronic information and cooperation system is needed that can be used as simply, reliably and trustworthily as fax and letters. Second, a strategic marketing plan is required that, starting with low initial investments costs and with European SME associations as multipliers, attracts a large amount of users from the start.The market success for such a system is expected to be quite good: a large number of users consul
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Age-related macular degeneration : assessment and optimisation of macular function with special regard to reading and motor control""' to be submitted under Fifth Framework.

assistant: **Abstract**

Age-related macular degeneration (AMD) is a disorder of high morbidity in Europe and will be an increasing problem in the next decades. The main objective of the proposal is the development of tools for testing and optimising macular function, which consider the disabilities caused by AMD, mainly disability of reading and motion control, in order to maintain or destitute these functions and therefore quality of life. These tools will provide a high sensitive monitoring of preventive and therapeutic measures (screening of early detection and assessing residual function). - These include psychophysical tests (e.g. contrast sensitivity, peritoneal letter recognition, figure/ground interaction, reading); eye movement recording with an eye tracker during fixation, reading, motion perception and exploration; assessment of fixation by Scanning Laser Ophthalmoscope (SLO); objective measurements by multifocal ERG linked with SLO for fixation control. The project will provide new knowledge about macular function and disabilities in AMD, which will be used for training. A test set will be established for a European standard for clinical low vision examination.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Demonstration of a cost-effective footwear based on shape memory materials to provide an instant fitting personalization service at the retail shop for enhancing user’s comfort' (DemoShopInstantShoe) under Seventh Framework.

assistant: **Objectives**

The DemoShopInstantShoe (DemoSIS) is a direct follow on from the very successful ShopInstantShoe FP7-SME-2008-1 project, that came to promising conclusions in February 2012. ShopInstantShoe (SIS) aimed at developing a customizable and fashionable women footwear upper and an innovative service providing customers with personalization of the shoe fitting at retail shop.SIS results revealed positive feedback from end users who assigned high value and expressed high interest on the proposed customizable shoes and in-shop personalization. Since the new product-service has been successfully created and validated at small scale, there is a strong case to demonstrate that the process and concept can be extended and able to overcome the barriers that are currently stopping the solution to be commercialized. The challenges to face in the project are:(1) To scale-up the range of upper materials to creating new smart textile based composites that facilitate to cover a wider footwear market segment.(2) To extend the footwear women models able to be personalized in order to fulfil the target needs and increasing the commercial scope of the product-service.(3) To develop the industrialization of the product manufacturing system.(4) To upgrade the novel customization process to a pre-commercial service, adapting the required customization shop tool to retail channel needs.(5) To validate the new improvements expected, including temporary in-shop pilot testing to reach the standard specification for the product-service, as well as outlining the most profitable business exploitation through further analysis.The new consortium is composed of four original partners from SIS project (Calzamedi, Texinov, Nimesis and IBV) and two retailing distributors (OrtoTwins and TechnoBoots). The outcome
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Innovative and practical management approaches to reduce nitrogen excretion by ruminants', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Dairying is an important sector of EU agriculture, but intensification has been accompanied by an increase in N surplus. This has a negative environmental impact on groundwater (pollution with nitrates), surface water (eutrophication) and on the atmosphere (de-nitrification and ammonia volatilisation). The EU seeks to stimulate measures that improve management of nutrients, waste and water as a start to move to management practices beyond “usual good-farming practice”. The objective of REDNEX is to develop innovative and practical management approaches for dairy cows that reduce nitrogen excretion into the environment through the optimization of rumen function, an improved understanding and prediction of dietary nitrogen utilization for milk production and excretion in urine and faeces. Novel tools for monitoring these processes and predicting the consequences in terms of N losses on–farm will be developed. At the centre of the project is a detailed mathematical model of N utilization by the cow which will act to integrate results from previous work and from new research carried out in the project. This interlinked research aims to improve the supply of amino acids to be absorbed relative to the quantity and quality of amino acids and carbohydrates in feed allowing a reduction in N intake. Research to understand amino acid absorption, intermediary utilization and the processes involved in the transfer of urea N from blood to the gastro-intestinal tract will further underpin model development and indicate strategies to reduce N losses. To predict N losses on-farm and the impact on profitability, a harmonised applied model will be derived from the mechanistic model and will be supported by tools to better describe feeds and biomarkers to indicate N status. Impact of the r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Toward enhancing activities of European institutions in the FDUSCC-IM cancer research joint institute in China' (IMMUNOCAN), addressing dissemination and exploitation.

assistant: **Impact**

The joint institute Fudan University Shanghai Cancer Centre – Institut Mérieux laboratory (FDUSCC-IM), created in May 2010, is conducting ambitious scientific research projects on oncology in China. Its 2 founding partners, Fudan University (China) and Transgene (part of Institut Mérieux, France) wish to increase their translational medical research cooperation with European countries.  In a first step, collaboration will enlarge to an active partnership with Danish, Italian and German teams, with the following objectives: (i) increase the EU-China knowledge exchanges in the field of cancer prognosis – by organizing in China summer schools, seminars and international conferences, as well as by hosting PhDs and post PhD research fellows in the joint institute, (ii) enhance the research capacity and the technological transfer to the joint institute – by providing adequate human resources and equipment to conduct beyond the state-of-the-art oncology research, (iii) promote a reference Euro-Asian centre on Chinese cancer prognosis – by spreading the knowledge and by raising awareness in China and European Union.Research activities will be held in China in collaboration with the new European partners, in order to enhance current research activities of the joint institute and to create durable links between Chinese and European teams. Current research is focused on immune phenotype as personalized medical biomarker for prognosis of Chinese cancer patients, and will be extended to new types of cancer and biomarkers. These prognosis studies will help to guide clinical decision-making by facilitating the selection of appropriate treatment options.Ultimately, this FP7 INCOLAB is an opportunity to build a Euro-Asian reference centre for medical and scientific research on cancer an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'CAMS EvOlution' (CAMEO).

assistant: **Concept**

Monitoring the composition of the atmosphere is a key objective of the European Union’s flagship Space programme Copernicus, with the Copernicus Atmosphere Monitoring Service (CAMS) providing free and continuous data and information on atmospheric composition. The CAMS Service Evolution (CAMEO) project will enhance the quality and efficiency of the CAMS service and help CAMS to better respond to policy needs such as air pollutant and greenhouse gases monitoring, the fulfilment of sustainable development goals, and sustainable and clean energy. CAMEO will help prepare CAMS for the uptake of forthcoming satellite data, including Sentinel-4, -5 and 3MI, and advance the aerosol and trace gas data assimilation methods and inversion capacity of the global and regional CAMS production systems. CAMEO will develop methods to provide uncertainty information for users of CAMS emissions, policy, solar radiation and deposition products in response to prominent requests from current CAMS users. CAMEO will contribute to the medium- to long-term evolution of the CAMS production systems and products. The transfer of developments from CAMEO into subsequent improvements of CAMS operational service elements is a main driver for the project and is the main pathway to impact for CAMEO. The CAMEO consortium, led by ECMWF, the entity entrusted to operate CAMS, includes several CAMS partners thus allowing CAMEO developments to be carried out directly within the CAMS production systems and facilitating the transition of CAMEO results to future upgrades of the CAMS service. This will maximise the impact and outcomes of CAMEO as it can make full use of the existing CAMS infrastructure for data sharing, data delivery and communication, thus supporting policymakers, business and citizens with enhanc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'The Application of Modern Proteomic and Metabolomic Methodologies in the Assessment of High Added-Value Traditional Meat Products'.

assistant: **Concept**

Food quality and safety are central to any society, having important economic, social and environmental implications. International comparisons have shown that the European Union is the world’s largest producer of food and drink products. It is not surprising therefore that the Agro-food sector has major importance/influence on the economy of Europe. The proposed research programme will give the researcher the opportunity to perform multidisciplinary activities that impact directly on food quality and safety. Experimentally the project will utilise recent advances in mass spectrometry and data analysis to develop modern proteomic and metabolomic approaches suitable for use in the assessment of traditional foodstuffs. To achieve these goals the following objectives will be addressed: (i) Development of a label-free quantitative proteomic method and metabolomic approaches to identify and quantify novel biologically active peptides with the objective to increase the health value of traditional meat products, (ii) study of the peptides generated at different time intervals during the processing of traditional Spanish dry-cured ham to correlate with the time of processing and use as safety and quality markers of the final product, and (iii) analysis the ‘omic’ datasets using independent statistical analysis (e.g. Principal Component Analysis (PCA) and ANOVA) and advanced proteomic-related software such as Mascot Distiller. The development of this project will enable the researcher to improve state of the art expertise in generic technologies, which are of strategic importance throughout Europe. The approaches developed will impact directly on the assessment of traditional foodstuffs advancing the present state of the art in the field. There is perfect synergy between the res
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'CROSSROAD - A Participative Roadmap for ICT Research in Electronic Governance and Policy Modelling'.

assistant: **Objectives**

Governments struggle to regulate an increasingly interdependent and complex world, as the financial crisis has shown. At the same time, citizens are becoming more vocal in monitoring and influencing policy decisions. Future scenarios are likely to show greater complexity and citizens' involvement. Current ICT tools for collaborative governance and policy modelling start to show great opportunities for decision-making in a complex world, but they still remain an exception rather than the rule, and research is fragmented between academic fields, application areas, and approaches to innovation (theory vs. practice led).CROSSROAD will deliver a research roadmap on ICT for governance and policy modelling, in order to orient towards a common goal the different communities of research actors, domains and sectors. It will create a shared vision and an operational tool to support research policy and research implementation in this field. The roadmap will be based on a cross-analysis of present research directions and future scenarios of collaborative governance, including possibilities for disruptive scenarios of extreme collaboration. It will be presented as a self-standing report and as an online, dynamic knowledge base.The CROSSROADS partners, with unparalleled experience in e-government and e-governance, web 2.0 and roadmapping, will involve a wide pool of expertise through an open, iterative, multi-method approach including in depth desk research, restricted workshops and large scale web consultations, in order to reach out to specialist research activities beyond the traditional e-government stakeholders and beyond Europe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Knowledge-based Sustainable Management for Europe's Seas' (KNOWSEAS).

assistant: **Concept**

Europe’s four regional seas (Baltic, Black, Mediterranean and NE Atlantic) have suffered severe environmental degradation due to human pressure. Existing measures to manage pressures have proven inadequate and the EC has responded by proposing a new policy (Maritime Strategy Blue Book) and environmental legislation (Marine Strategy Directive), both currently close to adoption. These instruments rely on the Ecosystem Approach, a management paradigm that encompasses humans and the supporting ecosystem. But the science base for this approach needs strengthening and practical tools must be developed and tested for policy implementation. In particular, criteria for assessing costs and benefits of management actions are poorly developed, particularly in the complex marine environment where multiple uses and management conflicts are common. The KnowSeas consortium will strengthen the science base for managing Europe’s seas through the practical application of systems thinking. It will work at the two scales envisaged for emergent EU policy: the Regional Sea Scale and Member State Economic Exclusive Zones (EEZs). We have developed a new approach of Decision Space Analysis to investigate mismatches of scale. Knowledge created through the FP6 European Lifestyles and Marine Ecosystems project, augmented with necessary new studies of climate effects, fisheries and maritime industries - in EEZ case studies - will provide a basis for assessing changes to natural systems and their human causes. New research will examine and model economic and social impacts of changes to ecosystem goods and services and costs and benefits of various management options available through existing and proposed policy instruments. Institutional and social analysis will determine conflicts of interest and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Behaviour near criticality' (Critical) under Seventh Framework.

assistant: **Objectives**

One of the main challenges of modern mathematical physics is to understand the behaviour of systems at or near criticality. In a number of cases, one can argue heuristically that this behaviour should be described by a nonlinear stochastic partial differential equation. Some examples of systems of interest are models of phase coexistence near the critical temperature, one-dimensional interface growth models, and models of absorption of a diffusing particle by random impurities. Unfortunately, the equations arising in all of these contexts are mathematically ill-posed. This is to the extent that they defeat not only ""standard"" stochastic PDE techniques (as developed by Da Prato / Zabczyk / Röckner / Walsh / Krylov / etc), but also more recent approaches based on Wick renormalisation of nonlinearities (Da Prato / Debussche / etc).Over the past year or so, I have been developing a theory of regularity structures that allows to give a rigorous mathematical interpretation to such equations, which therefore allows to build the mathematical objects conjectured to describe the abovementioned systems near criticality. The aim of the proposal is to study the convergence of a variety of concrete microscopic models to these limiting objects. The main fundamental mathematical tools to be developed in this endeavour are a discrete analogue to the theory of regularity structures, as well as a number of nonlinear invariance principles.If successful, the project will yield unique insight in the large-scale behaviour of a number of physically relevant systems in regimes where both nonlinear effects and random fluctuations compete with equal strength.""