RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Intelligently designed energy efficient buildings -assessment and control by an eco-factor system' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

The IDEEB concept aims to overcome non-technical barriers and increase the use of renewable energy and sustainable technologies on the European scale. The concept will be tested in office buildings to show that CO2 emissions can be reduced with 25% for retrofit, and 35% for new buildings and that the BEMS system can reduce energy consumption by 7%.The project also will improve quality of life, safety, health and working conditions with fulfilled requirements of indoor comfort. Reduce environmental impacts, specifically GHG. Reduce electricity consumption at peak loads. Secure and improve employment for the building trade specifically for control system manufactures by increased market prospects. Extension of quality assurance and environmental management schemes with the IDEEB concept.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Processing-in-memory architectures and programming libraries for bioinformatics algorithms' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Low cost, high throughput DNA and RNA sequencing (HTS) data is now the main workforce for various genomics and transcriptomics applications. HTS technologies have already started to impact a broad range of research and clinical use for the life sciences. These include, but are not limited to 1) large-scale sequencing studies for population genomics and disease-causing mutation discovery including cancer, 2) metagenomics, 3) comparative genomics, 5) transcriptome profiling, and 6) outbreak detection and tracking including COVID-19, Ebola, and Zika. HTS also impacts the whole health care system in several directions. Although there is still much room for improvement, sequencing of personal genomes is now becoming a part of preventive and personalized medicine as HTS technologies make it possible to 1) identify genetic mutations that enable rare disease diagnosis, 2) determine cancer subtypes therefore guiding treatment options, and 3) characterize infections and antibiotic resistance. Currently all genomics data are processed in energy-hungry computer clusters and data centers, which also necessitate the transfer of data via the internet, which also consumes substantial amounts of energy and wastes valuable time. Therefore there is a need for fast, energy-efficient, and cost-efficient technologies that enable all forms of genomics research without requiring data centers and cloud platforms. In this project we aim to leverage the emerging processing-in-memory (PIM) technologies to enable such powerful edge computing. We will focus on co-designing algorithms and data structures commonly used in bioinformatics together with several types of PIM architectures to obtain the highest benefit in cost, energy, and time savings. BioPIM will also impact other fields that employ simi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'PHOENIX: Precision Human Organs-on-chip for Enhanced Neuro-muscular and Cardiac Studies' (PHOENIX) under Horizon Europe.

assistant: **Objectives**

PHOENIX aims to revolutionise biomedical research by developing the next generation human-based Organs-on-chips (OoC). OoC is a promising technology potentially able to outperform conventional preclinical models in providing patho-physiologically relevant setting for investigating human diseases, thus tackling the limited translational value of animal testing. OoC wide adoption is currently hampered by poor maturation of cellular models and shortage of non-destructive readout methods. PHOENIX will take current OoC platforms to the next level, overcoming such limitations by integration of core technologies already validated by the Consortium, namely Electric Recording (3dMEA), Force Sensing (3dFORCE) and Mechanical Stimulation (3dMECH).Two platforms will be developed: i) μHeart, to model functional cardiac tissues, and ii) μNMC to model neuro-muscular circuits. PHOENIX ecosystem will be completed by satellite products and qualified against specific contexts of use in clinically and industrially relevant environments. PHOENIX potential will be showcased with two genetic pathologies as demonstrators: LMNA-cardiomyopathies and Freidreich’s Ataxia, conditions in which electrical instability and mechanical impairment play important roles. For each platform, two versions will be released (Base and Pro), addressing the need of identified customer segments (research labs and Pharma/Biotech).In line with the 3Rs, PHOENIX platforms represent the ideal clinically relevant tools to test drugs and gene therapies, leading to faster/safer development processes, reducing the need for animal testing. Robust dissemination, exploitation and communication activities will address both key stakeholders (OoC players, end-users, end-beneficiaries and regulatory bodies) and society at large, fos
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Coordination Of Network Descriptors for Urban Intelligent Transportation Systems'.

assistant: **Objectives**

The main objectives of this project are to develop Key Performance Indicators that assist European municipalities in business decisions for ITS projects and to facilitate best practice experiences between municipalities on experiences with ITS. An important aspect of the research is further to link the performance indicators to the current traffic situation in the cities. The project consortium consists of the transport authorities of five European cities (London, Paris, Rome, Brussels and Istanbul), three universities (Imperial College London, TU Munich and Technion), a private SME (ISIS Rome) and the networking organisation Polis. Technion will also provide data for the municipality of Tel Aviv. In addition to the project partners a group of other cities will be invited to join workshops and comment on the main results.   The project is split in three main work packages: Firstly, a review of ITS in European cities today, then an outlook on ITS developments in European cities tomorrow and thirdly the main work package concerning the establishment of KPIs. The KPI system to be developed is meant to comprehensively reflect a cities transportation situation. Therefore concepts to quantify improvements in traffic efficiency, traffic safety, environmental aspects as well as land use and the integration of disadvantaged population groups through ITS investments are to be considered. The robustness and usefulness of the KPI system is tested through case studies in London, Paris and Rome.  Deliverables of the project include a searchable web-tool on ITS functions employed in European cities, reviews on future R&D needs and the publication of a report on a feasible set of KPIs. Further, the project will explore the possibly to establish a ""city club"" that continues the CONDUI
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'MARine COastal BiOdiversity Long-term Observations' (MARCO-BOLO) under Horizon Europe.

assistant: **Objectives**

MARCO-BOLO (MBO) aims to structure and strengthen European coastal and marine biodiversity observation capabilities, linking them to global efforts to understand and restore ocean health, hence ensuring that outputs respond to explicit stakeholder needs from policy, planning and industry. To this end MBO will establish and engage with a Community of Practice (CoP) to determine end-user needs with the aim of optimising marine data flows, knowledge uptake, and improving governance based on biodiversity observations.By exploiting synergies with concurrent projects MBO will develop and demonstrate new autonomous technology for biodiversity mapping and monitoring, and data streams from remote sensing, eDNA, robotics, optical and acoustic observations. Protocols for eDNA-based biodiversity observations are established and validated across applications, taxa and ecosystems. The sequence of the analytical and technical processes for the different use cases will be incorporated into operational Essential Ocean Variables (EOVs) and Essential Biodiversity Variables (EBVs) and included into online reusable workflows, contributing to the free and open access of EU and global biodiversity information facilities, and to support major EU biodiversity directives and global initiatives.The project partnership will leverage its international activities (MBON, GOOS, OBIS) and participation in UN Ocean Decade Programmes (Marine Life 2030, OBON, ODIS, Ocean Practices for the Decade) to align the MBO work programme to global CoP, ensuring European participation and leadership in global biodiversity monitoring and global science. MBO results will be designed to build upon existing capability and infrastructures, and to be relevant to existing frameworks so that outputs can be easily integrated
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Production and distribution of food during the Roman Empire: Economics and political dynamics.' (EPNET) targeting Seventh Framework.

assistant: **Abstract**

The project aims at detecting and defining the political and economic dynamics of the Roman Empire trade system by designing and implementing an experimental laboratory to explore different historical hypoteses through computer simulations. Empirical data will be used to correct and validate the results of the simulations and define rigourous and falsifiable models of ancient trade sytems.The Roman Empire trade system is generally considered to be the first complex European trade network. Many theories and hypotheses about its organization have been proposed but no formal model has been put forward so far. We propose to study this system using complex network analysis, formal modelling and computer simulation. The different existing research hypotheses will be modelled in a formal framework that will be used for running computer simulations and create possible scenarios of the development of the trade network. The archaeological and historical datasets will offer the means for validation processes in order to verify the explanatory power of the different models and to choose the best-fitting representation of the investigated phenomena.The project counts with one of the richest database for amphorae and epigraphy, one of the most precise archaeological and historical semantic markers available for the Roman Empire market. They provide information on geographical origin, the products transported and traded, economic transactions, as well as the social position and relationships between the traders.The project will provide the research community with a powerful tool for the study and interpretation of past political and economic systems, which will benefit our understanding of long-term social trajectories. This will be achieved through an innovative methodology based on
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Large scope dissemination' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

The aim of the LSD project is to target a large number of SME interested in raising their competitiveness through an improvement of their development process. Rather than a specific focused subject, methodology, or technology, LSD aims at disseminating what is best perceived as complement need from the target audience. The action will also address companies only marginally involved in the IT business, but who seek in the IT sector, usually the most advanced, for an example on how to improve their development process.The ultimate objective of LSD remains the implementation of a solid network of local experts, not yet in the software domain, rather in that of the support of local SME. The language, when not jargon, spoken by software experts, in fact evolves so fast, according to the rate typical of the IT sector, that the gap between the software industry and its potential customers, is growing dangerously and too often suppliers and customers needs diverge. As a side, intermediate objective, LSD aims at growing the right skills for a prototype disseminator that will better guarantee for an effective penetration of the IT culture in any industrial sector, so to finally increase the demand for a better quality software and trigger the expected virtuous loop.ACTIONSLSD does not focus on a specific IT related subject. Rather the action will start with the large spread of a questionnaire aimed at gathering the most common needs shared by the target audience. It is expected to distribute this initial light questionnaire to about 1000 companies, and to receive it back from at least the 30% of the enquired companies.The outcome of the questionnaire will then be exploited to filter out the material currently available in different electronic libraries (e.g. VASIE). Such a materi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Smooth, REliable aNd Dispatchable Integration of PV in EU Grids' in the context of a Horizon 2020 call.

assistant: **Objectives**

SERENDI-PV proposes innovations towards two main pillars: (1) increased lifetime, reliability, performance and profitability of PV generation;  (2) utility-friendly high-penetration of the PV generation in the grids with improved stability, smart communication between stakeholders and increased knowledge of the PV fleet management.SERENDI-PV will develop advanced PV modelling, simulation and design tools,  monitoring data analytics for fault diagnostic and improved O&M, as well as lab and field testing Quality Control (QC) equipment and procedures for better assessment of the reliability of PV components and systems. The innovations will be developed with particular attention to the new PV applications that are becoming increasingly relevant on the market, such as bifacial PV, floating PV and BIPV.SERENDI-PV will pave the way towards higher PV penetration through a better understanding of the PV installed capacity, smart digital models for energy and services communication exchange between system stakeholders, the development of mid-term, short-term forecasting, and nowcasting for PV system aggregations, new business models for PV added revenue, and the creation of a collaborative platform for modelling, data analytics, QC, databases and grid integration.The solutions will be developed on the data from nearly 500,000 PV installations monitored within the consortium, representing a wide range of system sizes and typologies, including large ground-mounted PV plants, mid-size commercial and industrial PV systems, and small-scale rooftop residential PV systems. The results will be achieved through an interdisciplinary approach combining the complementary expertise of the 19 different partners that take part in the consortium and that represent all the relevant stakeholders
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Identifying the building blocks of episodic memory: how the hippocampus parses boundless experience into discrete events'.

assistant: **Objectives**

Life provides us with a continuous stream of information that ends up being organized in long-term memory as distinct events. How does this occur? Leading theories posit that surprising occurrences (when prediction of the immediate future fails) are interpreted by the system as event boundaries that segment ongoing experience. Will any type of surprise induce such segmentation? Moreover, how are these segments then laid down in memory as discrete units? The proposed research addresses these key issues in a two phase study, combining fMRI of healthy individuals with a neuropsychological study of amnesic patients, and using tailored film clips designed to dissociate between distinct forms of prediction error (PE) – low-level PE (salient perceptual changes) and high-level PE (explicit expectancy of an upcoming change). We hypothesize that the key region in this process may be the hippocampus, a region strongly linked to formation of episodic memory. Combining a 7T fMRI study (enabling distinction between hippocampal subfields) with a study of patients with focal hippocampal lesions will enable us to elucidate the nature and necessity of hippocampal involvement in segmentation. The significance of this study lays first in its potential to illuminate how real-life events are registered to memory, a process which is likely to differ significantly from the encoding of brief, simple stimuli that have been employed previously. The importance of studying encoding of complex events has recently received increasing recognition, yet this is still only at its infancy, with very few studies employing this approach. Combining the complementary expertise of the researcher and the host, the proposed research aims to identify what constitutes an event boundary in mnemonic processing. Thro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Breaking resistance of pathogenic bacteria by chemical dysregulation'.

assistant: **Innovation**

Antibiotic resistant bacteria are on the rise and could trigger the next global pandemic. For some pathogens no treatment options are left, leading to steadily increasing death tolls. The limited scope of bacterial targets, all essential for growth, has favored resistance build-up whilst also being ineffective against non-growing persister cells. To overcome this threat, innovative concepts are required to effectively and sustainably kill bacteria via unprecedented mechanisms.My team and I tackle this challenge by deliberately going beyond established modes of action (MoA). To achieve this, we present breakingBAC: a three-tiered chemical strategy to dysregulate bacterial physiology. First, we will develop small molecule  activators of crucial bacterial hydrolases to deregulate the degradation of proteins, leading to devastating physiological effects. Although enzyme stimulation has several advantages over inhibition, this concept is still in its infancy. We thus showcase principles of activator discovery and demonstrate their potency against diverse pathogens. Second, we recently discovered the complexation of free cellular heme by antibiotic isonitriles leading to a dysregulation of porphyrin biosynthesis and a corresponding induction of oxidative stress. Although these isonitriles are too large to access protein bound heme, we will tailor their structure to additionally target hemedependent enzymes of the stress response. The aim is to develop molecules bearing a dual MoA: a) stress induction and b) inhibition of stress response. Third, we will combine our learnings to create bifunctional compounds consisting of a hyperactivating protease recruiter linked to a bait which delivers the large class of essential heme-dependent enzymes for proteolysis. As these protein deg