RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on ''Vetulae'. Depicting women's ageing bodies in 15th century Florence'.

assistant: **Innovation**

This project aims to provide a holistic and comparative view of ideas and materializations regarding women’s ageing bodies in 15th c. Florence at the intersection of art, art theory, and medicine. Over the last few decades, studies on the biological, economic, social, and cultural aspects of ageing have multiplied, as a result of the ongoing debates on demographic ageing and its impact in our societies. Although recent shifts in scholarship have led to significant advancement in this area, biomedical accounts are often privileged over the social and cultural, and the latter tend to focus mostly on the contemporary. My project VETULAE supplies this central question in modern science with a historical depth and seeks to enrich the discussion with new perspectives. The project thus has the potential to play a part in influencing the way we think about women’s ageing by anchoring present and future experiences in historic precedents. More specifically, VETULAE aims to:1) Collect a corpus of pictorial and sculptural works that represent different facets of women's ageing and old age, executed in Florence and its surroundings during the 15th century; 2) Compare cultural constructions of women's ageing to that of men’s using texts and images from different social and iconographic contexts; 3) Reflect on the presumed gender bias in regards to ageing among physicians, artists, writers, and cultural promoters; 4) Rewrite the gendered ageing body into the history of pre-modern Europe, addressing the underestimated yet crucial role of the intersection between natural history and the visual arts in shaping cultural constructions of gender and age; 5) Inscribe pre-modern ideas about women’s ageing in the longue durée and evaluate their impact in today's culture.This research will be
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Uncovering the missing X factors to understand sex bias in cardiovascular disease' under Horizon Europe.

assistant: **Concept**

Cardiovascular diseases (CVD) occur and progress differently in men and women, and the risk dramatically increases with age. Hormone differences have been suggested to account for the sex difference by observing that younger women are regularly protected from CVD until post-menopause. However, hormone replacement therapies failed to provide cardioprotection, suggesting that other biological factors contribute to sex disparities in CVD development. Other likely contributors to sex bias are genes that escape female X chromosome inactivation, an understudied epigenetic phenomenon that has so far not been linked to sex differences in CVD. These so-called escaper genes have twice the gene dose in females compared to males and thus are likely to contribute to sex-based differences. EscapeX aims to identify sex-specific protective mechanisms by disentangling the impact of hormones and sex chromosomes on sex bias in CVD. First, we will combine the transgenic FCG mouse model, in which the sex chromosome complement (XX or XY) is independent of the gonadal hormones, with the pressure overload heart failure model, which shows a sex-specific phenotype. Next, EscapeX uses our established escaper detection pipeline to map and characterize escaping during cardiac aging and disease. The resulting dataset will uncover the escaper gene function, the extend of lineage-specific escaping, and how the escaper landscape changes during aging and disease. Building on those findings, EscapeX aims to overexpress the identified escapers in the disease model using viral vectors with the ambitious goal to rescue the sex-specific phenotype. Finally, we will combine allele-specific genomics and single-cell technology to explore if X-reactivation occurs in cardiac aging and disease and if such a novel d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'HUMAN ADAPTATION TO DIFFERENT ALTITUDES THROUGH TIME AND CLIMATIC CHANGES' under Horizon Europe.

assistant: **Concept**

The evolution of Homo sapiens has always benefited from its ability to adapt to the most diverse environments. The subject of the adaptation of human groups to the environment has been of interest to scholars, whose attention is often turned to cases of adaptation to environments with extreme conditions and to the so-called ecological niches. However, little attention has been given to the choice of human groups to occupy extremely different environments (high mountains, higher than 2000 meter asl vs lowlands) and how high altitude settlements relate to the lowland sites in the framework of the land management. This is particularly the case of the Finale Pleistocene to Mid-Holocene period in the Horn of Africa. HUMA will be the first project to fully explore the contribution of a multidisciplinary and integrated approach to the understanding of human adaptation to the different environments in the Later Stone Age of the Horn of Africa. This will be achieved by integrating the most up-to-date approaches in lithic techno-functional analysis with organic and inorganic residues analysis on lithic artefacts and dental calculus analysis. Focusing on archaeological sites from Ethiopian highlands (Beefa Cave, a site discovered in 2019) and Somali highlands and plains, Huma will investigate the role played by the climate played in the development of the cultural traits and how environmental factors may have fostered specific adaptations to different ecological niches and encouraged seasonal use of them.Lithic techno-functional analysis, Residues analysis, Archaeobotany, Experimental Archaeology, Dental Calculus analysis, and aDNA analysis will be applied in order to answer the research questions. Both the University of Florence and the University of Connecticut are the ideal env
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Omni-Supervised Learning for Dynamic Scene Understanding' to be submitted under Horizon Europe.

assistant: **Abstract**

Computer vision has become a powerful technology, able to bring applications such as autonomous vehicles and social robots closer to reality. In order for autonomous vehicles to safely navigate a scene, they need to understand the dynamic objects around it. In other words, we need computer vision algorithms to perform dynamic scene understanding (DSU), i.e., detection, segmentation, and tracking of multiple moving objects in a scene. This is an essential feature for higher-level tasks such as action recognition or decision making for autonomous vehicles. Much of the success of computer vision models for DSU has been driven by the rise of deep learning, in particular, convolutional neural networks trained on large-scale datasets in a supervised way. But the closed-world created by our datasets is not an accurate representation of the real world. If our methods only work on annotated object classes, what happens if a new object appears in front of an autonomous vehicle? We propose to rethink the deep learning models we use, the way we obtain data annotations, as well as the generalization of our models to previously unseen object classes. To bring all the power of computer vision algorithms for DSU to the open-world, we will focus on three lines of research:  1-Models. We will design novel machine learning models to address the shortcomings of convolutional neural networks. A hierarchical (from pixels to objects) image-dependent representation will allow us to capture spatio-temporal dependencies at all levels of the hierarchy. 2-Data. To train our models, we will create a new large-scale DSU synthetic dataset, and propose novel methods to mitigate the annotation costs for video data.  3-Open-World. To bring DSU to the open-world, we will design methods that learn directl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The only technology to successfully translate between signed and spoken languages' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Deaf people struggle in our society because of lack of technologies that can enable them to integrate in work and by using public and private services. There is a lack of human translators who can help them to overcome their barriers. Due to this unfortunately they can never achieve the same treatment as other and suffer from lower quality of life.SignAll Technology Ltd. from Budapest develops SignAll -  the first software-hardware solution in the world that enables spontaneous communication between a deaf persons and a hearing individuals via automated translation technology. SignAll Technology Ltd. has developed the first version of SignAll in the U.S. for American Sign Language (currently in pilot). Now, they want to adapt it and transfer the technology back and commercialize for European markets.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Shelf-Edge Advection, Mortality and Recruitment (SEAMAR).' (SEAMAR).

assistant: **Innovation**

SEAMAR is an multi-disciplinary study to develop a Bio-Physical Transport Model for the prediction of year-to-year survival during. the early life-history stages of the western stock of mackerel (Scomber scombrus) and hence ultimate recruitment strength.The study will be based on an existing transport model developed as part of the SEFOS programme, which included a simulation of the physical environment but did not take account of biological interactions. Growth and mortality rates in response to environmental conditions such as food availability and temperature will be incorporated in the model as functions of the biological and physical environment. This will take predictive modelling of pre-recruit survival beyond the current state of the art and will give a fundamentally more realistic simulation of the fate of the eggs, larvae and post-larvae of mackerel in their drift from the spawning grounds to the nursery areas and an improved ability to predict recruitment. The modelled drift and survival (recruitment) of the post-larvae will be related to the observed distribution and abundance from lagrangian studies, recruit surveys and to recruitment indices from VPA stock assessment models as validation of the model. This understanding, combined with known changes in spawning behaviour (timing, location and pattern), will allow the prediction of scenarios for successful mackerel recruitment and the establishment of operational models for stock management as proposed by IWC & ICES.Main tasks:1. To develop a Bio-Physical Transport Model for eggs, larvae and post-larvae of mackerel by incorporation of biological characteristics in a transport model.2. To define the distribution, behaviour, growth and mortality of eggs, larvae and post-larvae of mackerel and their interrelati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Mechanics of Programmable Matter' (MOrPhEM) under Horizon 2020.

assistant: **Objectives**

Shape-shifting systems would offer unique innovation capabilities which have inspired fiction and driven exciting science and engineering research over the past decades. Such adaptable, multi-functional, shape-shifting creatures that could freely assume any desired form, mimic natural or engineered systems and even perform tasks beyond the capabilities of any human or conventional machine are indeed exciting prospects which could change the way we see world around us and interact with it. Yet shape-shifting systems, which include soft and reconfigurable robots, remain in their infancy. We are still to estimate physical limits for such technology and thus remain unable to predict which of all the exciting potential applications are actually achievable.In this project, through a continuous interaction between Robotics, Soft-Matter Physics, Computer Science and Computational Mechanics, with my host, I will devise novel theories and algorithms, implemented in open-source software which will enable to effectively control shape-shifting systems. Such predictive and control tools remain the major obstacle to designing and constructing actual shape shifters with unique and adaptable properties.The impact of shape-shifting devices would span the whole of engineering and medicine.  Such systems could be used in communication and entertainment to physically reproduce virtual moving and interacting entities. In medicine, they could be injected into the blood stream, adapt to physiological conditions, enter   the most remote, sinuous and confined areas in organs, treat them or invest them with required enhancements, e.g. cochlear implants for earing aids.These exciting opportunities, however, require the ability to effectively control these shape-shifting and adaptable systems, whic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Models Of Patient Engagement for Alzheimer’s Disease - Sofia ref.: 115985'.

assistant: **Objectives**

The MOPEAD consortium has proposed a programme of work carefully aligned to the objectives of IMI2 Call to deliver a step-change in AD-related patient engagement (PE) strategies and a paradigm shift in early stage care. It aims to improve patient engagement in three categories: 1) Pre-clinical AD (the most important for prevention trials; 2) Prodromal AD (i.e. MCI with positive amyloid biomarkers); and 3) Very Mild AD. MOPEAD offers four different and complementary strategies, namely AD Citizen-Science, Open House Initiative (OHI), Primary Care Campaign (PCC), and Type 2 Diabetes (T2DM). It seeks subjects eligible for CT scan in all three mentioned categories. The central concept is to test and evaluate the four Patient Engagement models (Runs) to help identify patients at risk of AD in a five-country, multi-centre setting. It builds upon an already successful model, the Open House Initiative pioneered by the coordinator (FACE). Five countries (ES, DE, NL, SE and SL) have been selected to implement these models based upon relevant expertise; the consortium brings together partners for their potential to become long-term assets to European efforts to tackle AD challenges. The methodology involves enhanced pre-screening protocols to select individuals for conventional screening associated to an RCT. Eligible subjects will be invited to formal evaluation using a protocol consensus with EPFIA. MOPEAD possesses confident baseline metrics from which to measure progress and determine the efficacy of PE strategies compared to primary care. Although baseline data exists for only three of the four proposed models, the new model AD Citizen Science approach will add significantly to the holistic approach of the project. The proposal addresses the specific cross-border challenge of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Building on the International Year of Astronomy: Making young children aware of the Universe' in the context of a Seventh Framework call.

assistant: **Objectives**

EU-UNAWE responds to the outreach part of the Coordinating Action for FP7-SPACE-2010-1. It meets the specific requirements of the call (Section 1.1.2.4).EU-UNAWE exploits inspirational aspects of astronomy and space to interest very young disadvantaged children in science and technology, broaden their minds and stimulate European and global citizenship. The proposal builds on Universe Awareness (UNAWE), a unique, innovative and proven programme for children aged 4 to 10 years. It will exploit the achievements of European (EU) and South African (SA) space sciences to inspire, excite and stimulate young children, when their curiosity is high and their value systems are being formed. Specifically, EU-UNAWE will: - Train and empower primary school teachers in 6 countries to include astronomy and space topics in the classroom. - Develop and translate hands-on material, where appropriate emphasising EU and SA science and technology. - Provide a network for exchange of expertise and material between educators - Lay the groundwork for expansion of the programme throughout the EU, Associated Countries and ICP Countries. - Act as a showcase for EU and SA astronomy/space and related technologies, by disseminating the products among very young children, their teachers and their families. - Use astronomy/space products to stimulate awareness and strengthen public support for EU and SA space science research and technology. - Stimulate the next generation of EU and SA engineers and scientists, particularly girls. - Contribute to the integration of disadvantaged communities in participating countries. - Strengthen collaboration between EU and SA over mutually beneficial scientific, technological, educational and social topics. - Provide significant added value for Europe’s expenditure
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Transport, reactions and dynamic of heavy metals in contaminated marine sediments' (TREAD), addressing dissemination and exploitation.

assistant: **Impact**

New approaches for the risk assessment of marine sediments polluted by Pb, Cd and Cu will be assessed and expedited by a coherent programme of work. Recent advances in the understanding of carbon and metal reaction pathways in sediments that recognize the importance of their micro heterogeneity will be exploited. Newly developed planar optrodes, electrodes, and gel techniques that can measure the solute and solid concentrations at sub-mm spatial resolution will be applied to sediment mesocosms containing contaminated sediment. The 2D and temporal information on solute and solid structure will be compared with the structure of the microbial community that is responsible for the sediment heterogeneity. These data will provide the basis for the construction of a solute/sediment interaction model that, for the first time, allows a consideration of the processes occurring in three dimensions. This mechanistic base will make available for our end-users.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'R21/M-Malaria vaccine to extend the protection of Post-Discharge Malaria Chemoprevention in children recovering from severe anaemia: a randomised-controlled trial in Malawi, Kenya and Uganda' (R21-PD) targeting Horizon Europe.

assistant: **Abstract**

The overall goal of this project is to provide scientific evidence for WHO policymaking on the longterm efficacy, safety, acceptability and cost-effectiveness of using R21/Matrix-Malaria vaccine to extend the duration of malaria chemoprevention from 4 to 12 months in children recovering from severe anaemia in highly malaria-endemic areas in sub-Saharan Africa. This project will generate long-term safety and efficacy data  and also generate pharmacovigilance data on a currently registered vaccines of R21/M-malaria vaccine in a under-studied patient population group.Post-discharge Malaria Chemoprevention, a malaria control strategy recently recommended by WHO to reduce the risk of death or re-hospitalization in children recovering from severe anaemia. However this strategy only provides this protection during the first 3-4 months post-discharge, although their risk of mortality and morbidity extends over 12 months. This project will determine whether providing R21 malaria vaccine will provide this extended malaria protection.We shall conduct a randomised-controlled clinical trial in Malawi, Kenya and Uganda to determine whether providing a booster dose of R21 malaria vaccine will reduce death and re-hospitalizations over a 12-month follow-up period compared to providing PDMC over 3 months with a monthly treatment course of an antimalarial (DP) in children recovering from severe anaemia. We shall also conduct sub-studies in order to determine the immunogenicity, acceptability from the patient and providers’ perspective and the cost-effectiveness including a budget impact analysis of this intervention. Lastly, we shall engage local and international policymakers to facilitate uptake of our findings and possible policy adoption.


**Keywords:** severe anaemia