RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Mediterranean critical Infrastructure Resilience Engineering with Nature based solutions' in the context of a Horizon Europe call.

assistant: **Objectives**

The Med-IREN project aims to provide actionable demonstration on how to climate proof the Mediterranean critical infrastructures, across critical sectors, by introducing NBS both in terms of improving climate risk management and sustaining their business continuity to extreme climate change. The project will be showcased in five lighthouse regions across the Mediterranean, each corresponding to a present day challenge, that are aligned with regional policies and can constitute the EU as a global leader in the field.Med-IREN will cover different and diverse types of CI (energy, transport, water, ICT, social) ,  priority climate hazards within the Mediterranean, which is a climate hot-spot, and NBS interventions. In parallel, the interventions and solutions will be replicated into four more regions across the EU, covering the Mediterranean, Black Sea and Boreal regions. Med-IREN will also provide evidence how key enabling conditions, such as participatory governance and citizen engagement, novel forms of financing, innovative urban/landscape planning and capacity building will support regional systemic transformation nd provide the upscaling and replication mechanism within Mediterranean regions and beyond.  A high-end digital decision making support toolset will be developed, integrating data from multiple sources, both in-situ and E.O., applying state-of-the-science models, as well as providing unprecedented visualization and sensemaking capabilities for understanding and quantifying resilience through-out the infrastructure and NBS life-cycle. Med-IREN will rely on the integration of the research output of more than 15 European and National projects, that focused on the (climate) resilience of infrastructures, regional adaptation and implementation of NBS. Med-IREN is
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Port IoT for Environmental Leverage' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Ports are a great example of heterogeneous information hubs. Multiple stakeholders operate inside and outside them with different motivations and businesses. Although document and data interchange is already in place through Port Community Systems (PCS), the interchange is limited to official documentation and services of the Port Authority, such as custom declarations, import/export of cargo, and other formal documents. However, an effective integration of operational data is far from optimal in most ports, and especially so in medium or small ports, where budget is limited and IT services usually is outsourced.In contrast, the available operational data (resources tracking, container status, vessel operations, surface or berth available, air/water quality measurements,...) is constantly increasing and technology is getting inexpensive and widely available. However, the application of such systems is still single-entity centric, since the information is not shared, keeping the real potential of the Internet of Things (IoT) and Industry 4.0 hidden. The same holds for geographic areas surrounding ports, where Smart Cities  integrate various data systems and provide valuable services to citizens and  authorities.PIXEL will enable a two-way collaboration of ports, multimodal transport agents and cities for optimal use of internal and external resources, sustainable economic growth and environmental impact mitigation, towards the Ports of the Future. PIXEL will leverage technological enablers to voluntary exchange data among ports and stakeholders, thus ensuring a measurable benefit in this process. The main outcome of this technology will be efficient use of resources in ports, sustainable development and green growth of ports and surrounding cities/regions.Built on top of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Additive Printing for Cell-based Analysis'.

assistant: **Concept**

The Project will develop and commercialise the additive printing of cell-based analysis systems. The objective is to deliver consistent, scalable manufacturing of cell-based models used by multiple industry sectors to evaluate materials ranging from new drugs to healthcare products and functional foods. The target market is global and growing (CAGR 12%; estimated $4.2Bn in 2016). Additive printing will have positive disruptive impact, automating assay assembly and producing complex models needed by industry to improve the predictive value of cell-based analysis. Operational efficiencies and competitive pricing of printed cell products and services will win market share by making high-end analysis available to non-specialist users, whilst allowing wider integration of complex models into high-volume screening. The market advantage will be cost-effective testing and greater confidence in commercial decisions with strategic and financial impact.The Phase 1 business plan will be built on market data, IP/technology audit and financial planning arising from 8 years’ successful ACS cell-based business. Phase 1 shall also prototype assays printed with iPSC-derived hepatocytes aimed at high-value hepatotoxicity testing; prototypes will be moved to TRL7, and in Phase 2 to market-ready TRL9 with client-reactive design aided by beta testing with opinion leaders. Technical innovation will use ACS core skills in human cell culture and build on commercial partnership with the UK National Centre for Additive Printing. Phase 2 will extend the technology platform to other cell models, expanding product range and commercial value. Post-project, these will be marketed and sold by expanding existing operations: initial hepatotoxicity sales alone are forecast at €0.6M one year post-launch (0
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'INTEROPERABLE TOOLS FOR COOPERATION SUPPORT USING THE WORLD-WIDE WEB' (COOPWWW).

assistant: **Innovation**

CoopWWW provides a comprehensive set of tools for efficient multimedia group cooperation using the Internet-based World-Wide Web, with an emphasis on professional technical and management needs in varied contexts. To this end, it will focus on assembly and integration of state-of-the-art technologies and their ongoing adaptation to field-tested user needs. The project result will support shared workspaces, turning the Web from a passive information system into an active cooperation medium. Among associated tools and services will be desktop conferencing, and interfaces to directories and business information systems.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Particles in Turbulence: from tracers to rain formation' (PTURB).

assistant: **Innovation**

In this project, we propose to experimentally study the behavior of particles in high Reynolds number turbulent flows in an unprecedented and challenging way. To address this general topic, we will combine two of the best modern experimental techniques used to track 3‐D particle motion: Tomographic Particle Image Velocimetry (T‐PIV), and Particle Tracking Velocimetry (PTV). The T‐PIV (cutting edge technology, developed in collaboration with LaVision gGmbH) will be used to track passive tracer particles, giving us the 3‐D Eulerian flow field. On the other hand, PTV will allow us to measure the Lagrangian trajectories of different types of particles evolving in the same part of the flow. We will observe flows in different forcing geometries, from highly anisotropic to nearly homogenous. We will use classical polystyrene or glass particles (that can have various sizes and densities), but we will also use superparamagnetic" particles (designed in collaboration with INM Leibniz‐Institut fuer Neue Materialien gGmbH) in order to mimic the gravitational field g and vary its strength while keeping all other variables fixed. This will allow us to investigate certain aspects of cloud dynamics and rain formation. For the first time, quantitative measurements of the instantaneous flow field, together with Lagrangian tracks of particles with different properties, will be obtained simultaneously, at high Reynolds numbers. This will allow us to disentangle the complex coupling between particles and a turbulent flow by gauging the different terms in the Maxey & Riley equation (1983). These results could lead to a substantial improvement of the numerical simulations dealing with those problems by suggesting the correct approximations that must be done on the governing equation (or an ers
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'High quality spectral CT using sparse reconstruction methods'.

assistant: **Innovation**

The new generations of spectral computed tomography (CT) scanners provide energy-dependent information that could translate into higher contrast and material decomposition capabilities, among other benefits, not only improving conventional CT but opening new possibilities for medical diagnosis. However, fast development of spectral CT technology is not flawless. Narrow energy bins are required to achieve the desired energy resolution, which increases the noise ratio per energy bin. A promising solution is to use sparse CT reconstruction methods (SRM) to improve image quality without increasing radiation dose. To date, several SRMs have been proposed based on simulated or phantom data, but only a few studies have considered preclinical or clinical data. The objective of this proposal is to provide and optimize new algorithms for spectral CT that will be designed and validated on experimental data targeting specific high-impact high-potential applications. To this aim, the project will evaluate previously suggested SRMs and propose new SRMs. In addition, the project will introduce a novel method to validate SRM for spectral CT. On the last stage, the developed SRMs will be validated using experimental data from several spectral CT scanners. This research will contribute to the development of spectral CT, which is foreseen as a new revolution in clinical diagnosis.


**Keywords:** spectral CT, synchrotron CT, sparse reconstruction methods
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Nanoscale supramolecular assemblies: electrical and optical properties of single layer porphyrin assemblies', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

Molecules are potential building blocks for new optoelectronic devices. Much research is needed in order to understand how molecules with promising properties interact to form a higher order matter, and to be able to incorporate the self-assembled material into devices with interconnections to the macroscopic world. In this framework, we propose to study porphyrin molecules.These molecules, which play an important role in biological processes such as photosynthesis and oxygen transport, are also particularly attractive building blocks for the manufacture of advanced electronic and optical devices due to their good conductivity, their interesting optical properties and their tendency to form ordered structures in the solid state. Our investigation will aim at understanding how they self-organize on various surfaces and how the molecular structure of individual porphyrin molecules and the morphology of the assembly influence the global electrical and optical properties of the structure.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'A Thematic Network in Computational Fluid Dynamics for the Marine I ndustry'.

assistant: **Objectives**

This proposal concerns the implementation of a Thematic Network in Marine Applications of Computational Fluid Dynamics. Known as MARNET-CFD. The proposals have been prepared jointly by WS Atkins Science & Technology (GB) and SIREHNA (FR) as part of an exploratory phase for such a network aimed at establishing its potential size, structure, activities and overall feasibility. The exploratory phase has established that there is a wide consensus in the European Shipbuilding Industry in favour of establishing such a Thematic Network. Opinions were sought both through a widely disseminated questionnaire and by stimulating discussion with an outline proposal for such a Network. The latter was followed up by direct contact with organizations expressing an interest in joining such a Thematic Network on its Implementation. The result of these activities is a potentially large Thematic Network of over 34 organisations including shipbuilders. Classification Societies, Towing Tanks and Research Institutes, and Universities. The intention is that further growth in the Network will also be pursued. The key issues to be addressed are those of validation, the development of general application guidelines, the stimulation of research through the setting of Grand Challenge Problems' by the Industry, and the wider implementation of CFD throughout the marine industry. To meet this challenge, the Network would organise its activities around 6 technical areas, namely; steady ship flows, unsteady ship flows, propulsors, offshore engineering, marine aerodynamics and ship and offshore safety. Certain of these are already quite mature areas in terms of technical development, whereas others are yet to benefit fully, and are open to technology transfer and the sharing of know-how.In response to th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Recycling of asphalt and moulding sands for cut backs surface layers' under Fourth Framework.

assistant: **Concept**

The objective of the project is to substantially reduce energy consumption when laying out asphalt and to upgrade recycled asphalt to be used as surface layer. Furthermore, a number of tests will be performed where recycled asphalt is added to recycled products. The project will concentrate on cold asphalt layer in order to limit energy consumption as much as possible. A type of mixing equipment and laying unit must be developed to handle the new materials.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Spatio-temporal Organization and Expression of the Genome' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

This project investigates the two-way relationship between spatio-temporal genome organization and coordinated gene regulation, through an approach at the interface between physics, computer science and biology.In the nucleus, preferred positions are observed from chromosomes to single genes, in relation to normal and pathological cellular states. Evidence indicates a complex spatio-temporal coupling between co-regulated genes: e.g. certain genes cluster spatially when responding to similar factors and transcriptional noise patterns suggest domain-wide mechanisms. Yet, no individual experiment allows probing transcriptional coordination in 4 dimensions (FISH, live locus tracking, Hi-C...). Interpreting such data also critically requires theory (stochastic processes, statistical physics…). A lack of appropriate experimental/analytical approaches is impairing our understanding of the 4D genome.Our proposal combines cutting-edge single-molecule imaging, signal-theory data analysis and physical modeling to study how genes coordinate in space and time in a single nucleus. Our objectives are to understand (a) competition/recycling of shared resources between genes within subnuclear compartments, (b) how enhancers communicate with genes domain-wide, and (c) the role of local conformational dynamics and supercoiling in gene co-regulation. Our organizing hypothesis is that, by acting on their microenvironment, genes shape their co-expression with other genes.Building upon my expertise, we will use dual-color MS2/PP7 RNA labeling to visualize for the first time transcription and motion of pairs of hormone-responsive genes in real time. With our innovative signal analysis tools, we will extract spatio-temporal signatures of underlying processes, which we will investigate with stoc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Structural study on mitochondrial ribosome assembly in human cells' (ItohRibo) targeting Horizon 2020.

assistant: **Abstract**

Human mitoribosome represents a distinct class of ribosomes that has specialized in synthesizing exclusively 13 hydrophobic membrane proteins, forming the catalytic core of the respiratory chain. The mature mitoribosome is composed of 82 nuclear encoded proteins and three mt-rRNAs. It is postulated that mitoribosomes are formed in an intricate and well-defined hierarchical process, involving hundreds of proteins and RNA molecules working in cooperation and under tight regulation. However, a structural insight into this process is completely lacking and most of the trans-factors remain unknown. I propose to fill this gap by harnessing CRISPR/Cas9 for genome editing in combination with the state of the art methods in single particle cryo-electron microscopy (cryo-EM). By combining these techniques with biochemical characterization, I will reveal mechanistic insights into how mitoribosomal proteins are assembled in a cascade while nascent mitochondrial rRNA molecules are processed and folded. Since high resolution cryo-EM allows now a unique ability to investigate heterogeneous ribosomal populations and built de novo models, the proposed work will not only reveal the maturation states, but also currently unknown factors implicated in the process. On the other hand, the mitochondrion is compartmentalized into sub-organelle sections such as nucleoids, RNA granules, and membrane-related milieus, and they co-localize with various stages of the mitoribosome assembly. I will also use cryo-electron tomography (cryo-ET) to expand the scope beyond the mitoribosomal complexes and reveal the dynamics of the maturation process and transport mechanism of the assembly intermediates between the sub-organelle compartments. Our approach relies on the most recently developed methodologies a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Macrofaunal impact on microbial diversity and organic contaminant degradation in marine sediments' (MACROMICRO) targeting Sixth Framework.

assistant: **Abstract**

Marine sediments constitute important sinks in the cycling of persistent organic contaminants released into our biosphere. Yet, sediments storing old discharges have now become major environmental pollution sources accounting for the propagation of organic contaminants and subsequent adverse effects along marine food chains worldwide. Thorough understanding of sedimentary biogeochemical and ecological processes affecting organic contaminant fate is thus crucial for accurate predictions of contaminant effect s on marine food webs. Microbes, especially bacteria, are considered main organic contaminant degraders in sediments and are thus highly important for ecosystem decontamination. Our present understanding of microbial contaminant degradation in marine sediments is limited, yet macrofaunal bioturbation appear highly important, and macrofaunal burrow linings were recently identified as hot spots for the microbial degradation of organic contaminants.The main research objective is to explore the influence of burrowing macrofauna on microbial community diversity and microbial PAH (polyaromatic hydrocarbon) degradation in marine sediments. New molecular techniques (PCR-DGGE, RT-PCR) will be used to measure microbial diversity, and the presence/expression of microb ial PAH catabolic genes, along with traditional PAH degradation analyses. The fusion of molecular techniques, marine sediment ecotoxicology, and benthic ecology is a unique innovative aspect of the proposed research, involving extensive interdisciplinarity.Aside from creating new knowledge on macrofaunal-microbial structure-function relationships in sediments, essential for the management of marine resources and habitats globally, the proposed project will generate a new ecotoxicological research direction. The hi