RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'MAterials design at the eXascale' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Understanding, predicting, and discovering the properties and performance of materials is key to delivering the technologies that power our economy and provide a sustainable development to our society. For this reason, materials simulations have become one of the most intensive and fast growing domains for high-performance computing worldwide, with a recognized European leadership in developing and innovating the ecosystem of quantum simulation codes. MaX will target these lighthouse codes to address the challenges and leverage the opportunities arising from future exascale and post-exascale architectures, and to offer powerful paths to discovery and innovation serving both scientific and industrial applications.MaX includes (1) the core developing teams of the European lighthouse codes; (2) the HPC centres designing and hosting pre-exascale and exascale systems; (3) the main European companies engaged in the development of exascale technologies; and it brings (4) a sustained record in training and educating the community, and (5) in disseminating its resources under an extensive open-source model that includescodes, workflows, and FAIR data.These synergies will underpin the objectives of the present proposal, that aims to upscale the MaX codes and their performance to multiple heterogeneous exascale architectures; to endow these codes with innovative capabilities enabled by such architectures; to co-design the hardware and software in collaboration with the relevant European stakeholders; to enable turn-key simulation capabilities that meet the power of exascale resources and deliver the resilience needed; to disseminate the entire ecosystem of codes, workflows, and data; and to train and engage developers and users in fully leveraging such powerful instruments for dis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'COnvergence of fixed and Mobile BrOadband access/aggregation networks' under Seventh Framework.

assistant: **Concept**

Fixed and mobile networks have been subjects to significant technological and architectural evolutions in the past years, with e.g. deployments of 4G mobile networks and FTTH fixed networks, as well as significant increase in traffic demand and access bandwidth both in fixed and mobile access networks. All these network evolutions lead to enormous investments in independent network infrastructures (billions of €). In terms of usage, the difference between fixed and mobile access tends to diminish with more and more video streaming and the willingness of users to use fixed (Wi-Fi) interface on their mobile device. All these elements strengthen the motivation of operators to integrate fixed and mobile networks and make them converge in the perspective of 5G networks.Today, Fixed and Mobile Convergence (FMC) is mainly implemented at service level with all IP services and IMS, allowing a converged service control layer. Fixed and mobile networks themselves have been optimized and evolved independently from each other and the current network deployments are still reflecting this independent evolution.In contrast, COMBO will allow the convergence of fixed and mobile networks themselves. To achieve this objective, COMBO will define, develop and technically assess network scenarios organized around the concept of Next Generation Point of Presence (NG-POP) and which embody the most promising directions for FMC at network level. These proposals will lead to networks with a more effective distribution of essential functions and improved utilisation of equipment and infrastructures. So as to show experimentally the high potential of FMC for future networks, COMBO will develop proof of concept demonstrations including both a unified access / aggregation network and a Universal Acces
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Evaluation of alternative approaches for assessment of safety performance indicators for nuclear power plants'.

assistant: **Concept**

The objectives of the proposed Concerted Action (CA) project are:1. To review the state-of-the art and the existing approaches to collection and reporting of safety Performance Indicators (PIs);2. To Identify strengths and deficiencies of the existing practices in various countries;3. To identify best practices relative to the needs of the regulators and the utility organisations;4. To formulate the relationship between safety inspection and performance monitoring, as manifested the information obtained from Pis;5. To identify future research needs as related to incorporation of the risk impact of organizational aspects on nuclear plant safety performance;6. To develop a list of candidate methods and recommendations for future development and implementation guidelines.The CA will look at the development of methods including quantitative indicators to help maintain and improve safety of NPPs. It will also be seeking methods that can be used in a risk-based system and environment, and it will exploit PSA techniques for the development and use of meaningful Safety Performance Indicators (SPIs). The CA activity includes participation from regulatories and operators; therefore, it is expected that the proposed CA action will stimulate and enhance the process of identifying best practices in the field of traditional SPIs, commensurate with specific needs of regulatory authorities and utilities, towards risk-based safety performance indicators, including the development of candidate methods and recommendations for future developments, and preparation of relevant implementation guidelines. The CA activity is expected to facilitate the transition to risk-informed and performance-based regulations in Europe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'A new cardioprotective drug for acute treatment of myocardial infarction' (CardioProtectMI), addressing dissemination and exploitation.

assistant: **Impact**

Ischemic Heart Disease kills more than 1.7M people/year in the EU, the vast majority via a heart attack (Myocardial Infarction - MI). Heart failure (HF) is the major cause of death after MI with a prevalence of >26M individuals globally. While current treatment involving restoration of blood flow to the heart saves the MI patients life it also causes additional damage to the heart through an inflammatory reaction (reperfusion injury). ResoThers leading drug candidate, RTP-026, is an immunomodulating therapeutic aimed at resolving inflammation triggered during MI, thereby reducing damage to the heart and significantly decreasing risk of HF and death. Pre-clinical data suggests RTP-026 could reduce post-MI HF by >20%. A Phase I study has been conducted to determine safety and tolerability of RTP-026 in Healthy Volunteers. With the EIC we aim to validate RTP-026 clinical effectiveness by means of a Phase IIa patient proof of principle study and Phase IIb proof of concept study.


**Keywords:** Cardioprotective Drugs, Immunomodulators, Cardiovascular Diseases, Resolution of Inflammation,  Heart Failure, Myocardial Infarction
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Advanced signal-processing for ultra-fast magnetic resonance Spectroscopic Imaging, and Training'.

assistant: **Innovation**

Magnetic Resonance Spectroscopic Imaging - MRSI - is an emerging, non-invasive modality of Molecular Imaging that opens the way to in vivo mapping of metabolism. It will greatly contribute to combating major diseases (cancer, Alzheimer's disease, multiple sclerosis, etc), monitoring therapy, drug development. Spin-offs: food inspection, materials research. Till today, major obstacles to routine clinical applications of MRSI are 1) Long measurement time, several minutes minimal, 2) Low spatial resolution and low signal-to-noise ratio of metabolic images, 3) Considerable complexity of MRSI processing, analysis, and data visualization, 4) Sparseness of training facilities. Exploiting the strong synergy between signal processing and MR methodology, this proposal aims to pave the way to real-time MRSI. This involves - Cutting-edge MRSI signal-processing algorithms for quantitation and imaging of metabolites. This includes - A 'Virtual Scanner' based on Quantum Mechanics - Advanced Semiparametric Estimation - Innovative Graphical User-Interfacing - Ultra-fast Data Acquisition at the forefront of MR-methodology. - Innovative e-Training/ToK for young researchers and experts. FAST will contribute to establishing MRSI as non-invasive routine tool in the clinic for combating major diseases. An ultimate goal is MRSI during surgery. An innovative graphical user-interface with web-collaboration will enable interactive communication sessions, with data- and action-sharing, between multiple users. FAST is interdisciplinary and intersectorial and lends itself very well for Training/ToK in all facets of MRSI, with advanced interactive web-based and traditional methods. Partner expertise ranges from medicine to theoretical physics, via biochemistry, chemistry, physics, signal processing,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The functional role of feedback signals to mouse primary visual cortex' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Vision is fundamentally important in our daily lives, and 25% of our brain is devoted to it. Information from the eyes is quickly relayed to the primary visual cortex (V1), where neurons detect elementary features of images such as the orientation of edges within small regions of visual space. However, V1 neurons are not governed by feedforward input alone, but also receive extensive feedback projections from downstream visual areas. Despite their importance in vision, the function of feedback signals has remained elusive, although multiple roles have been suggested. Feedback could account for contextual modulation of neural responses or explain attentional enhancement of responses to behaviourally relevant stimuli. Direct evidence supporting these roles is lacking, largely due to methodological limitations. We propose to take advantage of new imaging and genetic methods that allow for the first time direct measurement of feedback signals. We will inject genetically encoded calcium indicators in secondary visual areas in mice to label axons and synaptic boutons of neurons projecting back to V1. We will then measure the activity of feedback projections with synapse resolution using high-speed two-photon calcium imaging during different behavioural states to establish the functional role of feedback. Specifically, we will determine what information is fed back to V1 by identified axons from functionally defined visual areas during passive and active viewing, during locomotion or navigation. Our results will provide fundamental information about the functional role of feedback signals during visual processing, and will be of great interest to a wide neuroscience audience, including neurophysiologists, psychologists, and computational scientists. Understanding the mechanism
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'European Australasian Thysanoptera Semiochemical Network (EATS Network)' (EATS) under Seventh Framework.

assistant: **Objectives**

The focus of the Europe Australasian Thrips Semiochemical (EATS) Network is to develop semiochemical-based tools for management of thrips of economic and quarantine importance.  The objectives of this programme are (1) to strengthen existing and develop new research partnerships through staff exchanges and networking between 4 organisations from the Netherlands, Spain, Austria and United Kingdom, and 2 organisations from Australia and New Zealand, and (2) to address key scientific issues to develop novel practical tools for border protection and sustainable pest management for important thrips species.  Thrips are tiny insects that cause direct damage and transmit viruses to agricultural and horticultural crops in Europe and readily develop resistance to pesticides. They require significant inputs of agrichemicals, creating risks to workers, consumers and the environment, and are of significant quarantine concern.  IRSES provides a unique opportunity to strengthen past collaborations and integrate new world- leading research teams with complementary expertise into a coherent international programme that collectively will provide effective synergies.  A range of semiochemical-based technologies (e.g. pheromones, kairomones and allomones) have been successfully developed by researchers around the world for the sustainable management of many large insect pests. However, until now these technologies have been under-exploited for small insects such as thrips. The EATS Network will exploit existing knowledge of underpinning concepts in chemical ecology and insect behaviour while bringing new knowledge on the biology and pest management of small insects. This approach will allow rapid progress to be made towards practical tools for management of this devastating class of insec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Co-designing Citizen Social Science for Collective Action' in the context of a Horizon 2020 call.

assistant: **Objectives**

CoAct proposes a radically new approach to face four “wicked” social global issues by engaging vulnerable citizens acting as in-the field competent co-researchers. The approach represents a new understanding of the underexplored field of Citizen Social Science and will result in the implementation of new or improved science-related policies. CoAct’s ambitious Research and Innovation activities will respond to issues related to Mental Health Care, Youth Employment, Environmental Justice and Gender Equality in Barcelona, Vienna, Berlin, Buenos Aires and in European Eastern countries. CoAct will define and develop a general framework for Citizen Social Science as a participatory research co-designed and directly driven by citizen groups sharing a social concern. The methodological framework will be first incubated in a consortium with Research Organizations,  NGOs and global networks of Open Science and Open Data activism. Expertises from Computational Social Science, Participatory Action Research, Citizen Science evaluation or Citizen-generated Data will be incorporated to conceive a transdisciplinary Citizen Social Science that place vulnerable citizens at the center of Research and Innovation cycles, as co-designers and co-researchers. Secondly, three mission-oriented Actions and at least three Research Pilots will be led by vulnerable citizen groups with the support of Knowledge Coalitions formed by public bodies, CSOs and social innovators. The common effort will harness novel, simultaneously global and local, socially robust knowledge and scientifically reasoned measures to promote social change. An Open Citizen Science toolkit, Open Source digital platforms, and Capacity Building activities to improve data and science literacy, including a PhD Summer School, will be
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Progenetic evolution in the deep-sea fauna' (PRODEEP) targeting Seventh Framework.

assistant: **Abstract**

The proposed 2-year project conducted at the University Museum of Bergen (Norway) will address the questions on the evolution of the deep-sea fauna. It will focus on the group of predominantly deep-sea polychaete worms from the subfamily Hyalinoeciinae with worldwide distribution, remarkable diversity at great depths, and possible progenetic origin. The project will study the morphology, taxonomy and phylogeny of hyalinoeciin polychaetes and will evaluate the role of progenesis within Hyalinoeciinae in their successful colonization of the deep sea. The project will be based on the unique and extensive collection of the deep-sea hyalinoeciins appropriate for the DNA analysis and will also utilize materials from a number of European research institutions. It will combine the methods of traditional taxonomy with the state of the art molecular techniques. This study aims to: (1) assess the morphological and genetic variation within Hyalinoeciinae; (2) assess the phylogenetic position of Hyalinoeciinae species with suggested progenetic origin; (3) trace the evolution of characters within Hyalinoeciinae; (4) develop a hypothesis on the possible pathways of the deep-sea invasion by hyalinoeciins. The expected results will: provide taxonomical revision of hyalinoeciins; advance understanding of genetic and morphological variation in polychaetes from various depth zones; advance knowledge in polychaete phylogeny; and contribute to understanding of the role of progenesis in the deep-sea fauna formation and evolution. The project will be among the first studies of evolutionary processes within deep-sea polychaetes, one of the dominant groups of organisms inhabiting soft-bottom deep-sea communities, and will significantly strengthen European excellence and competitiveness in this a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Harmonization of European Rail Rules for Operating ERTMS' (HEROE), addressing dissemination and exploitation.

assistant: **Impact**

Harmonising rules and regulations for the new ERTMS control-command system in nominal and degraded situations;Easing a fair competition by fixing common level of safety, particularly for degraded situations (by applying a common risk analysis method); Facilitate the transition period between existing control-command systems and ERTMS and identify legal obstacles to the harmonisation;Opening to all the European railways, involved or hoping to be involved in ERTMS, the results of this project by establishing prestandardised sets of rules and regulations in regard with each operating situation.The general approach of these complex tasks will remain very practical and closely linked with actual operating situations. %the determination of the new ERTMS rules and regulations, especially for the driver and the signalman;the ways to harmonise rules and regulations during the transition period; the study of safety problems related to rules and regulations;the tests of the results;the writing of prestandards and their dissemination.The major networks dealing with ERTMS projects are involved very early in the conception of rules and regulations in order to obtain a common agreement on them.The new procedures will be experimented on the three ERTMS test sites (F, IT, D). %The HEROE project has a strong link with the ERTMS control-command project, completing the ERTMS technical interoperability by setting the framework of the operational interoperability. As for drawing up safety rules and regulations the human aspects cannot be ignored, the HEROE project will have some interactive work with the HUSARE project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'European-mediterranean infrastructure co-ordination for earthquake seismology' (EMICES) under Fifth Framework.

assistant: **Objectives**

To coordinate different ongoing European implementations of e-science technology for real-time data exchange, improved rapid access to earthquake data and earthquake information we propose three specialised workshops. One on real-time (life") earthquake data exchange, one on distributed Object Oriented software and one on data exchange in the Mediterranean area. Improving earthquake disaster preparedness and seismic hazard estimations are the driving forces behind the new initiatives we aim to co-ordinate."