RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'A minimally invasive, outpatient treatment for Gastroesophageal Reflux Disease (GERD), resulting in permanent relief from both GERD symptoms and life-long drug dependency' to be submitted under Horizon 2020.

assistant: **Abstract**

Gastroesophageal Reflux Disease (GERD) is a digestive disorder associated with symptoms such as heartburn and regurgitation, and  reflux of normal gastric content like gastric acid and digestive enzymes. GERD is caused by a loss of integrity of the gastro-esophageal barrier known as the 'lower esophageal sphincter' (LES). This condition is one of the most common gastroenterological diagnosis in the European Union, with an estimated 15-20 Million daily sufferers. GERD today is typically treated with medications such as proton pump inhibitors (PPIs). Unfortunately, these anti-acid medications only ‘mask’ GERD symptoms, cause severe side-effects long-term, and about 20% of patients are non-responders. Importantly, they do not treat/cure the underlying root cause of acid reflux. For people who have severe GERD and do not respond tomedication, invasive surgical intervention remains the only option. G125 is the least invasive outpatient treatment for Gastroesophageal Reflux Disease (GERD). It is a permanent injectable bulking agent for the endoscopic treatment which enables cell growth in the Lower Esophagal Sphincter (LES), thereby providing long term cure for the debilitating symptoms of GERD. G125 uses a tissue-friendly (biocompatible)  microspheres made of Polymethylmethcrylate (PMMA) suspended inbovine collagen and an Elongated Flexible Syringe (EFS) which consists of an elongated catheter and a transition bore needle. The PMMA microspheres provide a permanent scaffold for stimulated fibro-vascular tissue ingrowth in the affected area. During the phase 1 project, a go-to-market strategy and a supply chain will be established, as well as furtherdevelopment plan will be drafted. Within the overall innovation project AscentX Medical will refine the endoscopic injection proc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'PELlets versus GRanulates: Irradiation, Manufacturing & Modelling' to be submitted under Seventh Framework.

assistant: **Abstract**

PELGRIMM is a 4 year project, addressing Minor-Actinide (MA) bearing fuel developments for Generation IV Fast Reactor Systems to support the Strategic Research Agenda (SRA) of the European Sustainable Nuclear Energy –Technology Platform (SNE-TP). Both options, MA homogeneous recycle in driver fuels with MA content at a few percent, and heterogeneous recycle on UO2 fuels bearing high MA contents, located in the radial core blanket, are considered. Two fuel forms (pellet and spherepac) will be investigated. Indeed, spherepac technology (that leads to production of beads that can be directly loaded in pins) is attractive regarding MA-bearing fuels as it would lead to a significant simplification of the fabrication process and to a better accommodation of solid swelling (compared to pellets) under irradiation. These developments extend Europe's leading role in this area.A total of 12 partners from research institutions, education establishments and industries will collaborate to share and leverage their skills, progress and achievements, covering a comprehensive set of investigations: fuel fabrication, fuel behaviour under irradiation through an irradiation test and the execution of Post Irradiation Examinations, modelling and simulation of fuel behaviour and performance under irradiation, from normal operating conditions to severe accidents, and finally by providing unique education and training possibilities.Finally, synergies will be sought with other ongoing European projects. Furthermore, the PELGRIMM project will contribute actively to the EURATOM’s contribution to Generation IV International Forum (especially SFR).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Advanced manufacturing of self-sensing bio-based membranes for environmental detoxification and revalorization' (SELFAQUASENS).

assistant: **Innovation**

Among the myriad of toxics that contribute to water toxicity, heavy metals derived from mining have a huge impact in our environment even at very low doses. In parallel, mines play a pivotal role in the industrial/technical development of our societies. Usually, mining acid drainages or polluted waters are accompanied by critical raw elements (CRE). Today passive disperse alkaline Dispersed Alkaline Substrate (DAS) reactors is one of the technologies (TRL-9) that blocks the scape of these toxic elements from mines. For instance, heavy metals and valuable metals (CRE) are concentrated at different levels of DAS reactors during operation.So, envisioning a technology able to develop a circular economy for mining water by coupling its remediation to the recovery of valuable resources concentrated in DAS is highly appealing from environmental end economic point of views. SELFAQUASENS project brings key academic and non-academic actors within and beyond EU to develop a modular self-sensing filter and membrane technology able to: (I) remediate heavy metals and salinity pollutions in mining water, (II) couple the remediation to the recovery of CRE and (II) sense the concentration of specific elements or groups of elements during the process.SELFAQUASENS joints varied interdisciplinary and intersectoral expertise in an International research and training network formed by 5 universities, 2 large scale research facilities, 2 research centers and 2 SMEs. As a result, the R&I system of Europe will be strengthened by an ambitious exchange and training program that covers all the research disciplines, sectors and international actors needed to achieve the objectives of the action. The project will have significant impacts in the short to long terms into the EU society, economy and en
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Gut microbiota impact on brain development and plasticity.' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The gut microbiota is characterized by a variety of microorganisms that live in symbiosis with our body and that play a key role in host immune system development and metabolism. Studies in adult germ-free mice suggested the influence of gut commensals on emotional behaviors and stress responses. However, the exact mechanism through which these bacteria affect brain function is largely undiscovered and, their impact on brain development is still a relatively unexplored territory. In my project I propose to investigate how the gut microbiota modulates brain development and plasticity using the established model of mouse developing visual cortex. To find if development and environmental stimuli affect intestinal bacteria, the gut microbiome of mice reared in standard condition (ST) or in an enriched environment (EE) that is known to modulate visual development, will be analyzed at different ages: before weaning (P15), after weaning (P28) and in adulthood (P60) providing for the first time a developmental timeline of the gut microbiota in mice. Then, I will perturb the microbiota composition through antibiotic treatment (ABX) or fecal transplantation (FT) in ST and EE mice, and assess visual cortical function maturation and ocular dominance plasticity. Dendritic spine dynamics analyzed by in vivo two-photon imaging and formation of inhibitory and excitatory neurons will be assessed in the primary visual cortex (V1) as morphological biomarkers of visual cortical development. Finally, in order to find the molecular mechanisms and mediators of gut commensals effect on neuronal circuits, I will perform a transcriptome analysis in V1 of ST and EE mice treated with ABX, or subjected to FT. My research will bring a substantial advancement in the field, revealing how the early int
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Pyrotechnologies of  Middle and Later Stone Age foragers in central Africa: a micro-contextual approach' (MicroAsh) targeting Horizon 2020.

assistant: **Abstract**

The ability to produce and control fire is a momentous technological development and one that is unique to humans. The ways in which early pyrotechnology evolved and varied amongst prehistoric foragers is, however, poorly resolved. The main objective of the MicroAsh project is to reconstruct Middle and Later Stone Age (MSA and LSA) pyrotechnology variability by focusing on three closed-space rockshelters located in the Kasitu Valley (Malawi), which show exceptional preservation of organic materials. My pilot studies have shown that ashes constitute the main sedimentary components at the selected sites, though individual combustion features are invisible based solely on field observations. Human remains have been retrieved from all three sites, with the apparent use of fire for ritual interment practices during the LSA. MicroAsh will apply high-resolution geoarchaeological techniques (micromorphology, µFTIR, GIS), to study (1) site formation processes, (2) the relationship between fire use and paleoenvironment, (3) variability in the use of fire for ritual and subsistence through time, and (4) site-use intensity. The project will create, and make openly available, experimental datasets on characterization of ashes from varied local botanical resources that are of use to research in similar archaeological contexts in Africa. The largely unexplored potential of using human-made residues will contribute to our understanding of the transition from MSA to LSA foraging strategies. My experience in geoarchaeological studies in Malawi will directly assist me on achieving the goals of this ambitious project. The array of technical and transferable skills I will gather through the completion of MicroAsh and the widening of my collaboration network will be key in achieving my futur
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Development and analysis of polymer based multi-functional bactericidal materials' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

90% of bacteria are found attached to solid surfaces forming structures (bio-films), that are inaccessible to drugs and antibiotics. These bio-films represent a major problem in European society in both industry and health care. Currently, however, we understand little about how these bio-films form and, more importantly, how they can be prevented. This lack of understanding means that patients often suffer ‘unnecessary’ and painful infections following the formation of such films on surgical implants and catheters. With the growing problem of MRSA and C. difficile in hospitals, and the cost of policing and hygiene measures, an understanding of how to prevent bacterial persistence in the hospital environment is critical to the sustainability of European healthcare.  A multi-disciplinary group of European experts have the common aim to understand exactly how bacteria attach to, and persist on both biological and inert surfaces.  We will use a range of biological and physio-chemical techniques to study several fundamental aspects of bacterial attachment. We will employ new molecular microbiology techniques to understand the genetic components governing the interaction of a bacterial biotic cell surface with the novel antimicrobial surfaces we create. Second, we will be using new nano-scale material science and physical chemistry techniques to create and understand these antimicrobial surfaces. This duel systems approach will allow us to theoretically model the processes of bacterial attachment and survival, which in turn will allow us to improve these surfaces in an iterative approach. We will generate intellectual property around the coatings and treatments used to derive the surfaces and develop these in collaboration with industry. The solutions will be designed specif
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Experimental Functional Android Assistant (EFAA)' (EFAA) targeting Seventh Framework.

assistant: **Abstract**

As the introduction of robots into our daily life becomes a reality, the social compatibility of such robots gains importance. In order to meaningfully interact with humans, robots must develop an advanced real-world social intelligence that includes novel perceptual, behavioural, emotional, motivational and cognitive capabilities. The Experimental Functional Android Assistant (EFAA) project will contribute to the development of socially intelligent humanoids by advancing the state of the art in both single human-like social capabilities and in their integration in a consistent architecture.The EFAA project proposes a biomimetic, brain-inspired approach. The central assumption of EFAA is that social robots must develop a sense of self as to overcome the fundamental problem of social inference. It is only in possessing the core aspects of a human-like self, that inferences about others can be made through analogy. The EFAA Biomimetic Architecture for Situated Social Intelligence Systems, called BASSIS, is based on our growing understanding of the neuronal mechanisms and psychological processes underlying social perception, cognition and action and will exploit the availability, amongst the members of the consortium, of a number of complementary prototype robot-based perceptual, cognitive and motor architectures. By integrating across these existing architectures, by directing focused effort on specific core problems, and by exploiting the availability of unique advanced real-time neuronal simulation and hardware, the impact of the EFAA project is assured.The EFAA project will apply and benchmark BASSIS on a mobile humanoid assistant based on the iCub platform. The resultant system, EFAA, will actively engage in social interactions and interactive cognitive tasks. To faci
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Optically-pumped magnetometer arrays for magnetoencephalography' (OPMMEG), addressing dissemination and exploitation.

assistant: **Impact**

Magnetoencephalography (MEG) is a non-invasive imaging technique for investigating human brain function, uniquely capable ofmeasuring brain activity with good spatial and temporal resolution. MEG operates by detecting magnetic fields naturally produced bythe brain, with no applied fields or injections. Epilepsy diagnosis is the most advanced clinical application for MEG. Six million peopleare affected by epilepsy in Europe alone, with about 300 000 new cases every year. Use cases for MEG are growing, for examplediagnosis of mild traumatic brain injuries (TBI), which represents more than half of the 2.5 million new TBI cases each year in Europe. Clinical use of MEG is at present limited to large hospitals and elite clinics due to space, cost and the need for specialized cryogenics technicians.Optically pumped magnetometers (OPMs) are a cryogen-free quantum sensor technology with extraordinary magnetic sensitivity.Relative to cryogenic methods, OPM provide a superior balance of sensitivity, size and proximity to the cortex, but have not yet beenimplemented in technologies that are simultaneously manufacturable at scale, high-performing, and cost-effective. OPMMEG willdevelop an OPM array that meets these requirements for wide-spread use of OPMs in MEG, and demonstrate its application tomagnetoencephalography.The project brings together world leaders in quantum sensor components and systems, commercial MEG systems and MEGapplications. OMPMEG will build a value chain from photonic devices to systems connecting all relevant stakeholders. The consortiumis composed of 2 SMEs, 2 world-class research organizations and 1 university from 3 European countries. The position of theseorganizations in their respective markets guarantees that the project results will be widely exploited
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Innovation by Law Enforcement Agencies networking' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The ILEAnet project will set up and develop a sustainable network of Law Enforcement Agency (LEA) practitioner organisations from all over Europe. The mission of this network will be to stimulate LEA capabilities to influence, develop and take up research, development and innovation (RDI) that is useful and usable for LEAs, and thereby help them to tackle the major challenges they face. The network will be organised around ILEAnet National Contacts (INCs) who will be in charge of federating the respective networks of practitioners, policy makers, academics, industrial players and other RDI stakeholders in their respective countries. ILEAnet will also operate as a community of people with a common interest in exchanging and collaborating with respect to LEA challenges and needs and LEA-centred RDI. Whilst the organisational ILEAnet Network will be focused – “top-down” - on specific challenges, the ILEAnet Community of people will contribute “bottom-up” ideas to produce innovative approaches to face newly arising challenges. An online community platform will enable professional social networking and mutual online assistance related to new solutions and best practice to address LEA challenges. The platform will support online and physical meetings and discussions, and will provide the infrastructure for efficient knowledge management. Synthesising top-down approaches and bottom-up ideas in iterative survey-organise-brainstorm-analyse-propose-discuss-poll processes, ILEAnet will build up a broad portfolio of RDI results and new RDI project concepts, and will deliver recommendations for future RDI policies. ILEAnet will hence catalyse innovation between LEAs and between LEAs, academics and industry. This will enable LEAs not only to take up mature results but also to prepare
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Creation and use of trust in virtual communities through reputation Management' (TRUSTREP) under Sixth Framework.

assistant: **Objectives**

The increasing size and complexity of computer systems today makes distributed and self-organizing systems an attractive proposition. This project examines how reputation management schemes can be used to monitor and manage these systems in a decentralized fashion.Reputation management is not a replacement of traditional security solutions and is instead a complementary strategy that works through establishing trust between members of a virtual community allowing them to collaborate so that they can provide each other with robust services and services that would otherwise not have been possible.We will look at the processes involved in the creation of trust, learning from past research in this area from several disciplines such as evolutionary biology, game theory, mechanism design, and social-network theory as well as various sub-disciplines of computer science such as E-commerce and peer-to-peer systems. We will also look at how online creation of trust differs from offline trust and the ways in which this t rust, once created, can be used and shared.Reputation management will be applied to a number of collaborative and community-driven applications such as collaborative content distribution and spam detection. In order to undertake these activities, the fellow, Anurag Garg, will spend the two years of the fellowship at the Distributed Systems Group at Trinity College, Dublin.The fellowship meets the programme objectives by attracting a world-class third country researcher to Europe. With research experience in three countries (India, US and Italy), he is ideally placed to foster new and strengthen old research collaborations through this fellowship.This fellowship will fit the researcher's training needs as the host institution provides the necessary environment to c