RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Presence research in action' (PEACH).

assistant: **Innovation**

An important objective of FET is the development of Presence technologies. Presence is an emerging field focusing on understanding the cognitive experience of being somewhere and developing technologies to generate and augment it (being someone or something, somewhere, sometime, without physically being there).By nature a deeply interdisciplinary field, Presence spans a wide range of subjects: from neuroscience and cognition to artificial intelligence, sensors and systems. This horizontal character makes Presence a fascinating and fertile interdisciplinary field, but it is can also stunt its growth, as researchers are scattered across disciplines and groups worldwide. A coordination activity promoting discipline connect, identity building and integration while defining future research and policy directions is needed. The first goal of the three-year long PEACH Coordination Action is to stimulate, structure and support the research community, with special attention to the challenges associated to the interdisciplinary character of the field, and to produce visions and roadmaps to support the construction of the Presence ERA.Secondly, because Presence research is set to produce disruptive technologies which can cause profound social impact and raise serious ethical issues, PEACH will analyse the relation of Presence technologies with society (trends, ethics, legal aspects), foster the contact of researchers with the market and enhance the Public Understanding of Presence research and technology.PEACH will achieve its objectives by providing an open central information point for all the stakeholders, using a working methodology based on Working Groups and Action Events (Consultation Meetings, Summer Schools, a Science Fair and an Industry Event), and with the support of Pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Development, integration and dissemination of animal-based welfare indicators, including pain, in commercially important husbandry species, with special emphasis on small ruminants, equidae & turkeys' (2007-2013) under Seventh Framework.

assistant: **Objectives**

Animal welfare is one of the topics that has consistently ranked on the top of items brought to the attention of governmental organizations and politicians across European countries. Concerns about animal welfare among European citizens are founded in well thought expectations from governments, industry and other stakeholders. The tremendous public scrutiny on animal welfare related issues put excessive pressure on lawmakers who are expected to offer rapid and effective solutions to perceived animal welfare problems. The need for rapid responses to address animal welfare issues has, oftentimes, pressured animal welfare scientists to develop suboptimal criteria to assess animal welfare and created a gap between fundamental scientific questions in this new scientific discipline and the applied aspects needed to attend the immediate public concerns. In this proposal our goal is to rescue the balance on the need for a science based approach to investigate animal welfare questions. We will develop and test animal based welfare, including pain, indicators in sheep, goats, horses, donkeys and turkeys. In addition we will engage veterinarians to study the relationship between diseases and animal welfare. We will also address more fundamental questions measuring husbandry factors that may affect pre-natal programming of adaptive strategies that my compromise the validity and reliability of welfare indicators. Finally we will integrate research, teaching and outreach activities through the Global Research and Teaching School (Hub) in Animal Welfare Science in order to promote sustainability fostering long-term competitiveness in the European animal industry through a transparent and inclusive relationship among stakeholders.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Equations in free groups' to be submitted under Sixth Framework.

assistant: **Abstract**

In this project we wish to explore theoretical, as well as practical, aspects of solving equations in free groups. We will first consider a particular type of equation that occurs while solving the endomorphism problem in free groups. We say that the endom orphism problem is solvable for an element W in a group G if it can be decided effectively whether or not, given U in G, there is an endomorphism of G sending Wto U. We aim to display a polynomial-time algorithm that solves the endomorphism problem in free groups and also analyse the endomorphism problem from the perspective of generic-time complexity as developed by Schupp, Kapovich, Myasnikov and Shpilrain.Another goal of this project is the classification of equations in free groups in the following sense. We call a group G separable with respect to a class of equations if, for every equation in the class with no solution in G, there is a finite quotient of G in which the equation has no solution. We want to determine what classes of equations the free groups are separable with respect to.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Truck with an Organic Rankine Cycle' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Fuel efficiency has become a priority for the whole truck industry as fuel represents more than 35% of the freight operators total cost of ownership. Saving 5% of fuel triples freight operators’ net margins and saves 6 tonnes of CO2 annually per truck. Knowing that one third of the fuel introduced in a thermal engine is lost as waste heat in exhaust gases, harvesting this huge quantity of heat to create additional energy represents an untapped opportunity to save fuel. EXOES wants to seize this unique business opportunity.During 7 years of R&D, EXOES developed the most strategic component of a waste heat recovery system (ORC): the expander. Branded EVE® (for Energy Via Exhaust), this very innovative TRL6 expansion machine was tested in representative environments labs by major truck manufacturers and worldwide Tier 1s. Such tests revealed an outstanding 5% fuel-consumption reduction (25% higher than competitors), what offers to the freight operators a payback period of less than 2 years. EVE® also allows truck manufacturers and Tier 1s to generate new revenues and margins. Thanks to its compatibility with any single truck platform, EVE® reduces their investment risks. With these advantages on its competitors, EXOES can target the worldwide heavy commercial vehicles segment.EXOES needs now to achieve a 5% fuel consumption reduction under real road tests via the DEMOTRUCK, to prepare the industrialisation of the EVE® expander in a design-to-cost approach, to design the manufacturing plant for key sub-components and to assess the maintenance interval (more than 1,000 hours targeted). These are prerequisites before signing the first licencing agreement with a Tier 1. Preparing the international replication in addition summarise the TORC objectives that will make from EXOES
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Development of a fully automatized production control process (based on barkhaüsen noise and artificial vision technologies) to manufacture ball and roller bearings in aeronautic industry' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

The objective of this research project consists in developing an automatized production control process by introducing the most advanced technologies in the areas:controls of MATERIAL controls of GRINDING ABUSE controls of INDUSTRIAL MEASURING METHODS controls of ASPECTS The objective is to set up the principles of a new PRODUCTION CONTROL PROCESS for manufacturing BALL and ROLLER BEARINGS in the aeronautic domains. New technologies of high efficiency level have to be demonstrated in industrial automatized processes as listed hereunder: NOISE OF BARXHAÜSEN ARTIFICIAL VISION EDDY CURRENT LASER Actually the techniques used in the industry must be in accordance with drastic quality specifications sheets, so the controls are generally executed on every piece of the production process. The control processes all along the different production steps, are actually manual, and visual, they are achieved not economically by people dedicated to. The cost of these controls tasks is high because the operations to carry out are numerous, long and slow. Moreover these tasks are tiring and not gratifying for the workers. An automatic control process, a fully integrated controls conveyor line, which will be separated of the other production lines, by the means of integration of high level new technologies will enhance the quality production required and the productivity needed to challenge the competition worldwide. The increasing quality level of the production of BALL and ROLLER BEARINGS will contribute to define new norms and to ensure a better security in the aeronautic sector.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'A comparative study of the structural and dynamical forces in orb webs during prey impact and under wind-loading' (WEBSTRUCT).

assistant: **Concept**

Spider orb webs are semi-permanent records of foraging behaviour making them ideal to examine the interaction of environmental conditions and behavioural decisions. The spider adjusts the detailed geometry of the web to a wide range of factors in order to tune the primary function of the web, prey-capture, while at the same time ensuring its structural integrity. Here I propose to study how orb spiders adapt their webs to the stability of the environment. Spiders that invest more are expected to be better in tuning web structure to match environmental conditions and are expected to show more complex adjustments in web-geometry to unpredictability than low investment spiders. Four goals will be pursued: (i) Comparative examination of the energetic costs of web-building for three ecribellate and one cribellate orb weaver using rather different web-silk integration. The cost of web-building is known to significantly higher than the material costs. (ii) Analysis of the effect of web costs on the adaptability to prey type and (iii) of the effect of web cost on the adaptability to wind-loading and wind predictability. The geometry of the orb and the web-building behaviour are both expected to depend on the predictability of the environment (iv) The use of finite element models in order to analyse prey impacts and wind-loading both as separate and integrated effects. The results are expected to be of considerable interest for both the design of biomimetically inspired light weight structures and the analysis of animal decision making.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'PIK3CA-Related Overgrowth Syndrome, Pluripotency, Expression in speCific Tissue and Secretion' (PROSPECTS).

assistant: **Concept**

Overgrowth syndromes (OS) are rare genetic disorders that can be either localized or generalized. In most cases, the mutations are not inherited but occur during embryogenesis leading to somatic mosaicism. The genes involved in OS are not well characterized but most appear to be part of the PIK3CA/AKT/mTOR pathway, a major actor in cell growth and proliferation. Among the different genes, gain-of-function mutations of PIK3CA have a prominent role. Patients with PIK3CA gain of function mutation (PROS) usually have complex tissue malformations, including abnormal vessels, anarchic adipose tissue, muscle hypertrophy and/or bone deformation. Currently, there are no specific treatments for PROS patients. Patients mainly receive supportive care including debulking surgery, sclerotherapy and nutritional support. PROS often result in severe disabilities with deleterious social consequences and premature death. We recently generated a mouse model of PROS that, for the 1st time, recapitulates the patient phenotype, identified BYL719, a PIK3CA inhibitor undergoing development in oncology, as a potential therapeutic for PROS and demonstrated the efficacy of this drug in our mouse model (Venot et al, Nature 2018). Based on these very promising results, we were authorized to treat adults and children suffering from very severe forms of PROS. The clinical outcome is very promising. Now, in this project, we will decipher the physiopathology of PROS, identify biomarkers and new treatments. To this aim, we will combine in vitro and in vivo approaches using very innovative technologies and new mouse models of OS. Consistently with my previous works, we will extend our findings to Human through our unique PROS Biobank. The accomplishment of this project may lead to the discovery of novel t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Role of the mitochondrial sirtuins, SIRT3 and SIRT5, in hepatic metabolism and pathology' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The function of the three mitochondrial sirtuins SIRT3, 4, and 5 is poorly understood at present. As a limited number of studies have focused on SIRT3, its exact function and regulation in mammalian physiology need still to be elucidated. Likewise, beyond its recently discovered role in the regulation of carbamoyl phosphate synthase 1 (CPS1), nothing is known about the function of SIRT5, one of the other mitochondrial deacetylases from the sirtuin family. The present research project proposes to elucidate the function of SIRT3 and SIRT5 in the liver, a tissue in which both sirtuins are highly expressed. To accomplish this we will achieve the following specific aims: first, generating mice that lack SIRT3, SIRT5, and both SIRT3 and 5 specifically in hepatocytes. Second, evaluating how altering SIRT3 and/or SIRT5 expression levels specifically in liver can affect the hepatic and organismal response to metabolic stresses such as diets rich in carbohydrates and fat, in proteins, or in ethanol, whose metabolism takes place mostly in the mitochondria and, for the most part, in liver cells. Finally, we want to study whether SIRT3 and SIRT5 are involved in liver tumor development: exposure to different tumorigenic stimuli as alcohol-rich diets or certain mutagenic treatments leads to a change in SIRT3 and SIRT5 activity and cellular localization; all this points towards a possible function of these proteins in liver tumor development, an aspect we want to study in this project.We expect that our research will elucidate the basic function of hepatic SIRT3 and SIRT5 in metabolism and cancer. The outcome of our work will not only be useful from a fundamental scientific point of view, but it will also pave the way to new therapies that target SIRT3 and/or SIRT5 or the signaling pat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Assessment of cognitive dysfunction in Multiple Sclerosis using the simultaneous acquisition of event-related potentials and functional magnetic resonance imaging during executive tasks'.

assistant: **Objectives**

Multiple Sclerosis (MS) is one the most important neurological diseases by virtue of its frequency, chronicity and tendency to attack young adults. Cognitive impairment may affect approximately all patients with MS, and has been reported to negatively impact employment, social functioning, quality of life, and the ability to perform instrumental activities of daily living, with a high social cost. Nowadays, the way the brain of people affected with MS perform a cognitive task is an enigma still unsolved. On the other hand, the integration of simultaneous event-related potentials (ERP) and functional magnetic resonance imaging (fMRI) is an emerging method in human brain mapping. Combining their complementary information both methods provide electrophysiological cerebral activity with high temporal resolution and hemodynamic response with high spatial resolution.  Our purpose in this research will be to improve the assessment of cognitve dysfunction among MS patients with different stages of the disease using the simultaneous acquisition of ERP/fMRI to obtain physiological and pathological brain activity. In addiction, this temporal-spatial information will be correlated with diffusion tensor imaging (DTI) scores, a new imaging method that provide markers to assess the macroscopic and microscopic pathology.  We have developed a detailed work plan including a first phase to verify the feasibility of co-recording of EEG and fMRI signals and a spatial-temporal description of the processing of stimuli. Thus, these achievements will allow us to obtain a powerful approach to assess performace of cognitive task in MS patients and further application in other neurolical disorders. Results of our ERP/fMRI study will provide unique insights on cognitive function in MS patients with
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Autonomous Linguistic Emergence in neural Networks' (ALiEN) under Horizon 2020.

assistant: **Objectives**

Deep neural networks (DNNs) are specialized computational models lacking a standard interface. If a complex task requires different DNNs, an ad-hoc connection must be laboriously designed. Inspired by human language, ALiEN wants to replace such ad-hoc interfaces with generic communication protocols optimized for ease of learning by DNNs that might have different architectures and functions. ALiEN “languages” are not hand-crafted: they emerge by training DNNs to share information through communication, offering the scalability and robustness to noise that is an asset of learned systems.A first set of experiments will study, in tightly controlled settings, the impact of input, training community size and communication channel on the expressiveness and ease of acquisition of emergent protocols. The emergence of general protocols will be encouraged by a training environment characterized by varied inputs and interaction among numerous DNNs. The best emerged protocols will also be taught in a supervised way to new DNNs, with the final aim of establishing a “universal” DNN language. Next, I will explore how emergent protocols can help interfacing out-of-the box, state-of-the-art DNNs, only requiring the addition of light input and output layers to existing pre-trained models.  Finally, a simplified home automation use case will demonstrate the usefulness of emergent protocols in a scenario that features some of the complexities to be expected in real-life applications. The project will also thoroughly analyze the emerging protocols, with the concurrent aims of i) identifying and favoring features that make them more expressive and easier to learn; ii) enhancing interpretability; and iii) gathering scientific insights into communication emergence in a non-human “species”.All i