RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Ground Operations of LIquid hydrogen AircrafT' (GOLIAT), addressing dissemination and exploitation.

assistant: **Impact**

Developing aircraft using hydrogen is seen as a major lever to reach net-zero CO2 emissions by 2050 and to secure the long-term sustainability of air travel. In order to enable a widespread development of hydrogen aviation, it is essential for airport operators that a future regulatory framework is implemented for the handling of large quantities of hydrogen at airports and that there is a clear understanding of how hydrogen-powered aircraft will be integrated into airport operations and the required changes to current aircraft ground handling operations are known. In parallel to this, and for industrial partners, it is also necessary to  develop new ground-handling equipment for hydrogen aircraft, and more specifically liquid hydrogen refuelling equipment that will enable safe and efficient turn-around operations. GOLIAT will demonstrate liquid hydrogen aircraft ground operations at three different types of European airports using a small hydrogen operated aircraft allowing the necessary procedures to be developed. It will also, through two demonstrators, showcase several critical technologies needed for future certified high-performance liquid hydrogen refuelling. In parallel, GOLIAT will answer key questions that will lay the foundations for the standardisation and certification framework of future safe hydrogen operations. Indeed, a key output of the project will be the gap analysis of certification rules and requirements for ground operations and equipment. Finally, GOLIAT will also assess the sizing and economics of hydrogen value chains for airports, critical for the competitive development of hydrogen powered aviation. To achieve its goals, GOLIAT reunites technology providers (aircraft manufacturers, liquid hydrogen suppliers, logistics experts, cryogenic compo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Laboratory Evolution of Virus-likE pRotein cAGes for Eukaryotic mRNA delivery'.

assistant: **Objectives**

Nucleic acids are promising candidates for treating disease by stimulating, inhibiting, or replacing other nucleic acids or proteins inside of eukaryotic cells—a process known as “gene therapy.” However, methods to efficiently and safely deliver genes into cells are still lacking. The problem is that nucleic acids are not cell permeant and degrade before reaching the cytosol. One way to transport oligonucleotides into cells is by packaging them into hollow containers made of proteins, a method that has been successfully hijacked by viruses for a long time.Here, we propose to design and engineer an artificial proteinaceous container that (1) selectively encapsulates ribonucleic acids (RNAs) using a known RNA recognition tag and (2) delivers this RNA into the cytosol of mammalian cells. Protein engineering, which embodies both rational design and computational modeling, will be used to create the starting design of this artificial protein container. The initial design will be based on the protein lumazine synthase from the bacterial organism Aquifex aeolicus (AaLS), which forms small but highly symmetrical nanocompartments in bacteria and is very tolerant to genetic changes. To optimize this design, we will use directed evolution to induce an artificial selection pressure on a large population of distinct capsid variants, allowing us to obtain only the best-performing capsid variants: those that can enter and disassemble selectively inside of mammalian cells, thereby releasing the enclosed RNA molecules into the cytosol. New AaLS containers will be thoroughly characterized using cutting-edge technologies, such next-generation sequencing and cryo-electron microscopy.The ultimate goal of LEVERAGE mRNA is to use the designed and evolved capsids to deliver messenger RNAs (mRN
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'High Temperature Energy Autonomous System' (HITEAS) targeting Seventh Framework.

assistant: **Abstract**

HiTEAS aims at developing an High Temperature Energy Autonomous System. the objectives of the project are to study, design and test an embedded system aiming at measuring strain or pressure, storing data in an embedded memory, communicating with RFID protocol when the aircraft is on ground and operating in a large range of temperature (from -30°C up to 250°C) within a few tens of centimeter cube limited volume.The project will especially focuses on:•ASIC design, in SOI technology, including pressure, strain sensor interface and power management•Energy harvester development•Antenna design
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'A Cognitive Detection System for Cybersecure Operational Technologies' (IDUNN) under Horizon 2020.

assistant: **Objectives**

Data is becoming the core engine of businesses. Data allows extracting, exchanging and sharing value out of the myriad of production and service chains that are no longer under a centralised distribution. As a result, an IT and OT convergence based on the integration of multiple ICT systems will transform market dynamics that present specific security challenges in a context of ever-accelerating change in terms of the threat landscape, attack surface, ecosystems, solutions and regulation.IDUNN’s main objective will focus on adding this trust ingredient to any business by making its ICT systems resilience to cyber-attacks. To achieve that, IDUNN will create a security shield in the form of tools, methodologies, microservices and initial standards compatible with any ICT supply chain. IDUNN will demonstrate a secure Continuity Plan for ICT based organisations by creating and validating a unique Cognitive Detection System for Cybersecure Operational Technologies.  Faced with a possible incident, IDUNN will know how to act quickly to alleviate it, and in turn generate a cognitive learning process, which reduces human intervention and provides forecasting capabilities.  In this respect, IDUNN will be capable of learning to protect themselves from new threats since they are constantly updated. IDUNN project will develop a complete integrated solution, modular and adaptative to different scenarios. Only when ICT systems behave securely, digital trust will be achieved.The deployment of IDUNN will (i) increase trust in ICT for both IT and OT, (ii) decrease person effort to ensure cybersecurity operations, (iii) increase response and lower recovery time, and above all, (iv) will have a crucial impact in the productivity of any businesses that make use of these secured ICT chains
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Polynomial Optimization, Efficiency through Moments and Algebra' in the context of a Horizon 2020 call.

assistant: **Objectives**

Non-linear optimization problems are present in many real-life applications and in scientific areas such as operations research, control engineering, physics, information processing, economy, biology, etc. However, efficient computational procedures, that can provide the guaranteed global optimum, are lacking for them. The project will develop new polynomial optimization methods, combining moment relaxation procedures with computational algebraic tools to address this type of problems. Recent advances in mathematical programming have shown that the polynomial optimization problems can be approximated by sequences of Semi-Definite Programming problems. This approach provides a powerful way to compute global solutions of non-linear optimization problems and to guarantee the quality of computational results. On the other hand, advanced algebraic algorithms to compute all the solutions of polynomial systems, with efficient implementations for exact and approximate solutions, were developed in the past twenty years.The network combines the expertise of active European teams working in these two domains to address important challenges in polynomial optimization and to show the impact of this research on practical applications. The network will train a new squad of 15 young researchers to master high-level mathematics, algorithm design, scientific computation and software development, and to solve optimization problems for real-world applications. It will advance the research on algebraic methods for moment approaches, tackle mixed integer non-linear optimization problems and enhance the efficiency and robustness of moment relaxation methods. Specific applications of these approaches to optimization problems are related to smarter cities challenges, such as water distribution
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Neurofilaments in Health and neurodegenerative diseases' (NeuroFish) under Horizon 2020.

assistant: **Objectives**

Neurofilaments (NFs) are a highly dynamic cytoskeletal network, which exhibits essential functions in neurons and are key actors in neurodegeneration. NFs are not only a genetic cause of neuronal death in human, their abnormal aggregation is an early pathological hallmark in disease, and their genetic removal from axons has shown spectacular benefits in delaying disease onset, extending survival and restoring neurological functions in mouse models.  In this project, I propose the concept that the defects in NF transport and degradation are the causes of neurodegeneration. I will tackle the live dynamic of these processes in health and disease in a meaningful in vivo context, using the zebrafish. Combining state-of-the-art and innovative live-imaging and proteomic methodologies in zebrafish, our program has three major goals. First, we will study the dynamic of NF transport along the axons and its spatial regulation by myelinating cells, with novel zebrafish lines expressing fluorescently labeled NFs. Second, we will decipher the mechanisms of NF degradation by generating a zebrafish line overexpressing gigaxonin, an E3 ligase adaptor we found to destroy the stable NF network, and by designing a new proteomic methodology in zebrafish. Finally, we will investigate NF dysfunctions and their pathological roles in disease, by generating models for neurodegenerative diseases carrying NF mutations and using the methodologies described above. I anticipate that interventions on NF dynamics will substantially reverse neurodegeneration, and proofs of concept will be obtained by overexpressing gigaxonin in our disease zebrafish models and through drug screening.  Thus, this ERC project will generate forefront knowledge in the field of NFs and neurodegeneration and will provide a hi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Reactive oxygen species (ROS) as Elixirs against chronic Disease: OXidative regulatory mechanisms  In T cells and neutrophils.'.

assistant: **Innovation**

We are proposing a four-year programme of knowledge transfer and networking between University of Surrey (SURREY, UK), Aston University (ASTON, UK), Friedrich-Alexander Universitat (UKER, Germany) and Redoxis AB (Redoxis, Sweden). The project targets an emerging area of biology, i.e. reactive oxygen species (ROS)-mediated regulation of immunology and ageing; it brings together the application of small molecule candidate drugs to generate ROS and uses innovative approaches to biomarker identification in models of chronic immune disease. This research has significant potential for application in human health and is of particular relevance to the ageing population.Training, knowledge transfer and skills exchange in this emergent area is important to extend the EU’s reach through cutting edge expertise. Interchange in this way will facilitate and promote early career researcher development into tomorrow’s research leaders. It will encourage new, cross-European collaboration between academia and industry. This tri-partite consortium brings together groups with very complementary expertise for knowledge exchange to benefit early career researchers: ASTON – in the biochemical analyses of ROS; SURREY in thiol oxidation and effects in vitro and ex vivo on and within immune cells relevant for biomarker development in chronic disease; UKER - in animal models of chronic diseases such as systemic lupus erythematosus (SLE) and arthritis; and Redoxis on development of novel drugs that stimulate production of ROS from the NOX2 enzyme as means to modulate chronic inflammation. The project objectives and challenges present a balanced mix between industrial application and basic science, with a focus on knowledge transfer and drug development. Through future collaborative funding, we anti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Constellation: The origin of Stellar Masses' (CONSTELLATION).

assistant: **Innovation**

CONSTELLATION will bring together 12 European teams and recruit 17 young researchers to attack some of the key problems concerning the origin of stellar masses. The scientific goals of the network are concentrated in three main tasks: the fragmentation and collapse of molecular clouds into clusters and aggregates of protostars; the formation of massive stars and their impact on their surrounding environment; the form of the low-mass and sub-stellar mass function, and the physical characteristics of brown dwarfs and planetary-mass free-floating objects.The most important aspect of the scientific work is that each task combines multi-wavelength observational studies with state-of-the-art numerical simulations and theoretical modelling, making full use of the wide range of expertise, experience, and access to world-leading observational and computing resources within the network. In addition, CONSTELLATION will also involve integration with ongoing European e-science and 'virtual observatory' projects, and a unique schools-based outreach programme.The young researchers employed in the network will enjoy exposure to and training in a broad range of problems in this key area of astronomy, with access to leading ground- and space-based observing facilities and supercomputers optimised for astrophysical fluid simulation. Through their involvement in distributed, network ed science and a series of schools, workshops, secondments, and conferences, they will gain important knowledge and experience from the CONSTELLATION network, as well as playing a central role in its success.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Numerical study of dynamics and magnetic properties of strongly correlated electron systems'.

assistant: **Objectives**

Strongly correlated electron systems are in the forefront of contemporary physics due to both fundamentally open issues and the application of such systems in modern electronics, spintronics, and quantum information technology. However, successful application and unravelling of the fundamental phenomena require further studies which can only be performed with powerful numerical simulation techniques.Herein, we intend to investigate the dynamic and magnetic properties of strongly correlated electron systems with the recently developed continuous-time quantum Monte Carlo (CT-QMC) simulation method. This is a very powerful numerical method which significantly advances the limit of conventional quantum Monte Carlo methods. The applicant recently acquired expertise in this field during a longer stay in Japan and she will install this method at the host institution and apply it with the following objectives: study of (i) anomalous rare-earth compounds with exotic multipole orders, (ii) attractive fermionic models such as the N-flavour attractive Hubbard model, and (iii) compounds with the 5d transition metal ion Ir, the so called iridates, where the spin-orbit interaction is strong. The expected results will contribute to the better understanding of correlated behavior such as unconventional insulating states or Kondo effect which can be efficiently dealt with by the CT-QMC method in contrast with other numerical methods.This bridging between the applicant's previous workplace in Japan and the host institution in Hungary provides knowledge transfer and fruitful collaboration. This will also contribute to counteract brain drain between Europe and overseas and to strengthen a host in a less favoured EU region. The applicant's expertise with the theoretical study of strongly cor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Systemic Innovations for a SusTainable reduction of the EuRopean food waStage' (SISTERS).

assistant: **Concept**

Only in the EU, we generate every year around 89M tonnes of Food Loss and Waste (FLW), accounting for 20% of the total foodproduced, with costs estimated at ?143 Bn, impacting each stage of the Food Value Chain.In SISTERS, we propose a set of systemic innovations addressed to reduce FLW generated in every stage of the Food Value Chain inEurope that will solve main existing challenges in Production, Processing, Marketing (retailing/wholesaling), Consumption, and theLogistics among stages.SISTERS will design the 1st European Short Chain Platform for farmers to sell their discarded production, favouring local economies,providing access to nutritious and healthy food to the less favoured consumers. Smart and reusable food containers will be designedto diminish food losses during transportation, maintain bulk and packed food in ideal conditions with new accurate sensors allowingimmediate reaction. Moreover, to improve the preservation and quality of food a set of bio-based and home-compostablepackaging solutions will be created reducing their potential negative impacts in the environment. A novel SISTERS Seal ofExcellence will promote sustainable practices among retailers. While the information provided to the consumers with QR anddynamic labelling incorporated in the packaging is expected to impact on retailers and consumers sustainable awareness, thusreducing the discard of food and associated FW. With these cross-sectorial innovations, we will achieve an ambitious environmental& economic impact of the current dynamics in the food system, contributing to the reduction of FLW and to change theunsustainable consumer behaviours. With the support of the EC, SISTERS will be a key EU project addressing the problem in a holisticway, reducing FLW by 27.4% and CO2 emissions by arou
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'UNIVERSITY SCIENCE AND SMEs IN RUSE REGION', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

The proposal aims at bringing the researchers of Ruse University closer to the business and socio-economic reality of the region: SMEs and their managers on one hand, students, citizens and studying and presenting the SME needs in terms of innovative way s to solve technological problems by using the local scientific potential in order to better match the scientific potential and the scientific needs for economic growth in the region, on the other hand. This will also lead to involving students in real l ife projects that will help them create contacts with local SME managers and become their employees after graduating the University. A large audience of citizens of various ages will be involved in the discussions foreseen during the implementation of th e project: starting with school students, then University students and professors, company managers. A Business& Science Club will be established to encourage the academic people and company managers to match and work together. Special attention will be given to the work with the journalists in order to catch their interest on the existing problems and also to make them promote the good practices.