RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Synthetic Methods in Program Verification' (TypeSynth).

assistant: **Concept**

TypeSynth: Synthetic Methods in Program VerificationSoftware systems mediate a growing proportion of human activity, e.g. communication, transport, medicine, industrial and agricultural production, etc. As a result, it is urgent to understand and better control both the correctness and security properties of these increasingly complex software systems. The diversity of verification requirements speaks to a need for models of program execution that smoothly interpolate between many different levels of abstraction.Models of program execution vary in expressiveness along the spectrum of possible programming languages and specification logics. At one extreme, dependent type theory is a language for mathematically-inspired functional programming that is sufficiently expressive to serve as its own specification logic. Dependent type theory has struggled, however, to incorporate several computational effects that are common in every-day programming languages, such as state and concurrency. Languages that support these features require very sophisticated specification logics due to the myriad details that must be surfaced in their semantic models.In the context of dependent type theory, I have recently developed a new technique called Synthetic Tait Computability or STC that smoothly combines multiple levels of abstraction into a single language. Inspired by sophisticated mathematical techniques invented in topos theory and category theory for entirely different purposes, STC enables low-level details (even down to execution steps) to be manipulated in a simpler and more abstract way than ever before, making them easier to control mathematically. Perhaps more importantly, the STC method makes it possible to import ideas and techniques from other fields that seemed more distant
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Materials for Avalanche Receiver for ultImate SEnsitivity'.

assistant: **Concept**

Avalanche photodiodes are key components for many applications (telecom, ranging, sensing, spectroscopy,...) because their internal gain improves the photoreceiver sensitivity considerably. Two III-V materials of interest have emerged: AlGaAs and AlInAs, lattice-matched to GaAs and InP, respectively, and both characterised by a wide bandgap. In recent years, a breakthrough in the impact ionisation characteristics was identified and the major importance of a thin avalanche multiplication layer was clearly demonstrated.MARISE ambition is aiming to develop innovative engineered APD components with thin avalanche layers to benefit from their promising characteristics likely to advance the present state of the art. MARISE objectives are to push the limits of the new APDs in two directions: speed and sensitivity.For 10Gb/s access and single photon detection, AlInAs/GaInAs will be developed exhibiting low dark current and high responsivity,The development of a very challenging evanescent waveguide APD structure in the same material system will allow for 40Gb/s operation with a record gain-bandwidth product of 200 GHz.AlGaAs will be combined with a GaInAsN absorber into an innovative, very low noise and potentially low cost GaAs-based APD, suitable for 1.3 µm telecom applications.In MARISE, the APDs characteristics will be thoroughly assessed, and their suitability will be investigated for the following large-scale applications:· 10Gb/s burst-mode photoreceivers for broadband access and local area networks,· Core networks receivers at 40Gb/s based on waveguide APDs,· Single photon detection for use in secure communications.For each application, the impact of improved APD performance will be demonstrated in terms of increased receiver sensitivity and bandwidth, extended network
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Discrimination Norms Enforced and Disrupted by Social Networks: A Research Program Using Simulation and Experiments' (0DISCRIMINATION) under Seventh Framework.

assistant: **Objectives**

Recognizable traits (gender, ethnicity, hair color) often provide a basis for negative discrimination, even if there is no statistical basis for differentiation. Still, people act differently towards persons with different traits, as if they had different qualities, for instance with regard to work efficiency. This leads to severe conflicts if discrimination provokes prejudice and stigmatizing that in practice mostly target asymmetrically members of one, disadvantaged category. The proposed research program enriches existing theories about the emergence and maintenance of discrimination by a new perspective: it aims to model mechanisms based on social network relations and incorporates them into the explanations. It tries to find answers under which structural configurations discrimination practices are likely to occur and under which network conditions they can be best avoided. For answering these questions, innovative methodologies will be used: agent-based simulation and experiments. These techniques have only been used to a limited extent targeting the problem of discrimination, but offer a huge potential to extend our limited insight into social mechanisms that maintain discrimination practices. With the help of these methods, the proposed research tries to delineate conditions under which an endogenous breakdown of negative discrimination is promoted by social networks. Particular attention will be devoted to cases of fierce intergroup opposition, in which network segregation is aligned with negative discrimination. Results are expected to help forming efficient policies for fighting discrimination and segregation. The practical objectives of the application are to further develop the skills of the applicant in applying these methods with a help of leading experts
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Discovering how bioactive compounds from seaweed kill parasitic worms' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Infection with gastrointestinal parasites is one of the most severe impediments to sustainable meat and milk production from grazing livestock. Widespread resistance to the small number of available synthetic drugs has rendered continued prophylactic drug treatment unsustainable. One solution is to feed animals on plants or other natural resources that contain bioactive compounds with anti-parasitic activity, such as seaweeds. The in vitro anti-parasitic activity of polyunsaturated fatty acids (PUFAs) from seaweeds has been reported, but as yet, the anthelmintic mechanism of PUFAs is unknown. The current proposal aims to use PUFAs from Nordic seaweeds to investigate how PUFAs bind to nematode parasites and target the receptors. Furthermore, transcriptomics and functional biochemical experiments will be used to elucidate the biological pathways that are perturbed in nematodes after exposure to sub-lethal doses of PUFAs in vitro. This unique multidisciplinary project will involve leading groups in both veterinary parasitology and receptor biology and combine the latest techniques in molecular parasitology and drug-receptor biology. It is envisaged that the unique skill sets obtained from the project will be highly beneficial to my future career, as well as uncovering novel insights into the biological properties of PUFAs that will greatly aid the practical future use of PUAFs-containing plants and algae, thus ensuring the continued sustainability of pasture-based livestock production.


**Keywords:** Seaweed, fatty acids, parasite, anthelmintic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Letting up senescence and inflammaging  through T cells' (2021-2027), addressing dissemination and exploitation.

assistant: **Impact**

With the increase in human life expectancy, there is an urgent need to understand the common molecular pathways by which aging results in a progressively higher susceptibility to chronic morbidity, disability, and frailty. In the last years, immunometabolism has emerged as a new field to boost immune responses for cancer immunotherapies as well as to dampen autoimmune diseases. A recent discovery from my lab has revealed  the critical role of T cell metabolism  in accelerating the onset of age-associated diseases and multimorbidity. This finding has opened a new path to investigate the diverse T cell intrinsic and external stimuli that instruct T cell differentiation towards a dysfunctional state during aging, with the final goal of designing effective strategies to promote healthy aging. LetTBe will  address the hypothesis that the time-dependent deterioration of T lymphocytes contributes not only to immunosenescence but also to the general aging process. The LetTBe project proposes to use multidisciplinary approaches to target age-associated T cells for preventing inflammaging, senescence and age-associated multimorbidity. Our central goals are: 1) To define age-associated T cells heterogeneity with special focus in their cellular origin, clonality, metabolic vulnerabilities and transcriptomic signatures; 2) To decode the environmental signals that are imprinted on age-associated T cells and contribute to their development; 3) To identify new strategies to targeting age-associated T cells for slowing down immunosenescence, and  for boosting resilience to inflammaging, systemic senescence and age-related multimorbidity. In sum, LetTBe puts forward an ambitious but feasible program with the wide purpose of understanding the specific molecular mechanisms and metabolic re
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The influence of spatial fluxes on meta-ecosystem dynamics: theorical perspectives and practical applications along the river-sea continuum' (RIVERSEA), addressing dissemination and exploitation.

assistant: **Impact**

Global environmental changes often transcend traditional boundaries between terrestrial, freshwater, and marine ecosystems, with many species and nutrients moving across these borders. Despite this, biodiversity and ecosystem functions are typically studied in isolation, and policy goals such as the UN Sustainable Development Goals (SDGs) often address these ecosystems separately. To address this issue, the RIVERSEA project proposes a novel approach by integrating meta-ecosystem science, which accounts for the interconnectedness of ecosystems and aims to enhance our understanding of how spatial fluxes of nutrients and organisms impact meta-ecosystem structure and dynamics.RIVERSEA seeks to elucidate the effects of nutrient and species fluxes along the river-sea continuum, focusing on how these fluxes influence food-web structure, ecosystem functioning, and stability. Nutrient enrichment from sources like agricultural runoff and sewage disrupts these meta-ecosystems over large spatial distances, leading to simplified food webs, nutrient accumulation, and detrimental outcomes such as harmful algal blooms. This project aims to bridge the gap between community and ecosystem ecology by developing a spatially extended food web model to explore these dynamics. It will also use innovative methods to validate theoretical predictions with empirical data, assessing the impacts of human activities on aquatic ecosystems. Finally, RIVERSEA will formulate restoration strategies to mitigate these impacts and stabilize meta-ecosystems.The project’s outcomes will provide crucial insights and tools for effective mitigation, adaptation, and restoration efforts, contributing to the EU’s goals of restoring significant land and sea areas by 2030 and 2050. By combining theoretical and empirica
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Portable air analysis device for on-site pest detection during plants import controls'.

assistant: **Innovation**

The current plant inspection process is labour intensive due to visual assessments, low detection throughput and the need for physical sampling for molecular- or antibody-based detection kits. SenseApest will address these challenges by screening imported plant material systematically and efficiently with a non-contact portable detection unit (PDU), based on volatile organic compound (VOC) emissions.Plants release VOCs in response to pest attacks, while pests emit their own distinctive VOCs. In senseApest, we propose to exploit these VOC biomarkers to develop a high throughput PDU equipped with VOC sensors, an algorithm, and a database. The PDU will enable rapid (<15 min), non-invasive and non-destructive screening of imported plant material for serious pests.The project emphasizes high-accuracy, user-friendliness, cost and time-efficiency, and portability in the design of the PDU. Two analytical modules will be developed to detect a wide range of VOCs, adding a layer of specificity to broaden the spectrum of detectable pests. Miniaturized components will be integrated into the PDU, ensuring high analytical performance while maintaining portability.The PDU will be validated into operational environments (TRL7). The collected data will train an algorithm in recognizing pest specific VOC biomarkers, enhancing diagnostic accuracy and applicability. The project aims to reduce false positives and false negatives in pest diagnostics while providing a method prioritizing efficiency in terms of analysis time and unit cost. Ultimately, the PDU is intended to be a cost-effective, user-friendly, adaptable, and efficient tool for plant health inspectors during import controls. To achieve this, a multi-actor interdisciplinary approach will be implemented.Adopting the PDU is expected
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Remote sensing and geo informatio n processing in the assessment and monitoring of land degradation and desertification in support of the UNCCD; state of the art and operational perspectives'.

assistant: **Innovation**

In the past years, the persisting threat of desertification and degradation of natural resources has resulted in a large number of initiatives and research efforts on a global scale, including the United Nations Convention to Combat Desertification. Despit e significant progress, knowledge still remains fragmented in many fields, especially with respect to the definition of related indicators or early warning systems. The specific support activity Remote Sensing and Geoinformation processing in the assessme nt and monitoring of land degradation and desertification in support of the UNCCD. State of the art and operational perspectives", intends to serve as a platform to bring together leading scientists working in the fields of remote sensing and geoinformatic s with a focus on desertification and land degradation with potential users. A dedicated conference striving for attention on a world wide level will be the core around which various other activities are assembled. Commissioned studies in specific target f ields will provide an overview on the state of the art, being complemented through methodological and application studies. Besides taking care of a sound scientific management and logistic organisation of the conference, major efforts will be dedicated tow ards the international visibility of the event and its results by providing for a high-level dissemination following different pathways {abstract book/CDROM, special issues of scientific journals, printed conference proceedings). A web site will provide f urther dissemination of the project as well as dynamic elements. Following principles set forth by the Commission under the ENRICH initiative and the quest to strengthen the European Research Area, the project will address renowned scientific experts, and supp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Safe green solvents for the future: in silico predictive chemometric models for selected toxicity endpoints of ionic liquids' to be submitted under Seventh Framework.

assistant: **Abstract**

Ionic liquids (ILs) are a modern addition to the world of chemical compounds, deployed in areas ranging from electrochemistry, over organic synthesis, to cleaning, extraction and separation technology. Their unique negligible vapor pressure, non-flammability, enhanced thermal stability and outstanding solvation potential make them ‘‘green’’ solvents. However, their toxicity needs to be understood and controlled, which is a challenge. Indeed, countless possible cation-anion combinations create billions of possible ILs, which calls for a rapid and reliable toxicity prediction. This can only be achieved through computation. Quantitative structure-property relationships (QSPR) solve the problem created by the current stringent environmental regulations and the impossibility of costly and time consuming experimental determination. This is why the EU-implemented REACH regulation recommends valid QSPRs for predicting ecotoxicity when experimental data are not available. In the present project, ecotoxicological models for ILs will be developed in silico, obeying OECD principles, based on available toxicity data against various endpoints.  Considering the ever growing interest in ILs, truly predictive QSPR models will be highly advantageous in designing desired ILs. We emphasize proper external validation, partially through new and stringent statistical measures. We combine this attitude with our two complementary strengths: physicochemical parameters rooted in quantum chemistry and rigorous chemometrics. Both the host and researcher have long experience in ecotoxicological QSAR modelling  and they have expertise in complementary areas ensuring true transfer of knowledge. The project also aims to establish collaboration with experimental toxicologists of the University of Manche
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Warm working for high silicon electrical steels' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

Objectives and content:Electrical steels are used in sheet form in electrical transformers and motor cores. Both transformers and motors unproductively dissipate, or loose, a portion of the applied electrical energy. These losses could be significantly reduced by the introduction of new low loss materials, containing a higher silicon content than do conventional alloys. However, increasing silicon content introduces processing difficulties and increases costs. Hence their widespread introduction has been inhibited. The proposed programme is aimed at exploring the feasibility of reducing the cost of higher silicon content steels and assessing the consequential benefits of doing so. Novel processing routes will be investigated and new designs of motors developed to capitalise on the reduced electrical losses. These will be achieved through research into the warm working and electroplastic processing of warm worked high silicon steels containing up to 6.5% silicon. Motor laminations will be manufactured from these steels and built into novel motor designs. This will enable the impact of the new steels in motor manufacture and performance to be assessed.The major research tasks are:- Introduce novel modifications (electroplasticity) to the conventional fabrication route for high silicon steels containing up to 6.5% silicon;- Develop a warm working process based on Transverse Flux Induction Heating technology for high silicon steels containing up to 6.5% silicon;- To realise the final thickness of 0.5 mm for high silicon steels through a combination of hot and warm rolling;- To manufacture and characterise novel motors designed to capitalise on the enhanced properties of the higher silicon steels. The success of this project will also lead to considerable reduction in energy