RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'DROPLETS AND EMULSIONS: DYNAMICS AND RHEOLOGY' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The applications of micro- and nanofluidics are now numerous, including lab-on-chip systems based upon micro-manipulation of discrete droplets, emulsions of interest in food and medical industries (drug delivery), analytical separation techniques of biomolecules, such as proteins and DNA, and facile handling of mass-limited samples. The problems involved contain diverse nano- and microstructures with a variety of lifetimes, touching atomistic scales (contact lines, thin films), mesoscopic collective behaviour (emulsions, glassy, soft-jammed systems) and hydrodynamical spatio-temporal evolutions (droplets and interface dynamics) with complex rheology and strong non-equilibrium properties. The interplay of the dynamics at the different scales involved still remains to be fully understood.The fundamental research I address in this project aims to set up the unified framework for the characterization and modelling of interfaces in confined geometries by means of an innovative micro- and nanofluidic numerical platform.The main challenging and ambitious questions I intend to address in my project are: How the stability of micro- and nanodroplets is affected by thermal gradients? Or by boundary corrugation and modulated wettability? Or by complex rheological properties of the dispersed and/or continuous phases? How these effects can be tuned to design new optimal devices for emulsions production? What are the rheological properties of these new soft materials? How confinement in small structures changes the bulk emulsion properties? What is the molecular-hydrodynamical mechanism at the origin of contact line slippage? How to realistically model the fluid-particle interactions on the molecular scale?The strength of the project lies in an innovative and state-of-the-art numerica
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Searching the Social Web' (SOCWEB), addressing dissemination and exploitation.

assistant: **Impact**

From its beginnings as a means to share scientific data, the Web is evolving to capture parts of daily life for millions of users. A large amount of user-generated content on a number of topics, people and their connections to other people and content are placed on-line daily. Within this new ecosystem there are two important new trends that bring a paradigm shift to how information is searched and accessed on the Web. First, users are increasingly using the Web to accomplish complex information searching tasks that may involve other users: e.g. the purchase of a house, or planning a vacation. When working towards such tasks, users oftentimes have the (currently unmet) need to coordinate, collaborate, and consult with other users. The second trend is the growing use and availability of social media data. Such data, is often structured and contains information such as reviews, rankings, trust scores, etc. which can be linked together into some form of Social Network (SN), based on friendship-links and user interactions. Such data can be particularly useful for tailoring the search results to the interests of a given user and for identifying users that are knowledgeable and potentially helpful around a given topic. We propose to investigate how Social Networks can improve the daily life of users while searching and accessing information on the Web. We will organize our research around the following thrusts. a) SN Data Management: How can we efficiently manage the constantly evolving social Web data? b) Social Searches: How can we enable users to save and share their Web searches with other users? c) Socially-Aware Results: How should we take into account a user's Social Network during Web searches? d) Social Trust: How can we tell which user is trustworthy and knowledgeab
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Education as Welfare - Enhancing opportunities for socially vulnerable youth in Europe'.

assistant: **Innovation**

The ITN 'Education as Welfare - Enhancing opportunities for socially vulnerable youth in Europe' aims to consolidate research on education and welfare and evaluate its capacity to tackle the multiple challenges and pressures a large proportion of young people in Europe faces. In examining the welfare dimensions of educational settings and the educational dimensions of welfare services, it integrates welfare and educational perspectives into a coherent approach for theoretical analysis and public policy. By focusing on universal conditions of human development, this approach warrants international applicability. It produces knowledge that facilitates the enablement and social integration of young people facing economic, social and personal barriers after leaving compulsory schooling. The scientific objective of the research and training programme is to identify factors with which to extend young people’s opportunities and capabilities in work, autonomy and participation -- the central dimensions of welfare. The ITN will combine and synergise the interdisciplinary research experience and professional capacities of leading European university departments and social, economic and political actors. Alongside their own research projects, the Early-Stage Researchers will design and conduct a comparative Education-as-Welfare survey that will serve as one fundament of their methodological training. The five non-university partners will especially ensure the dissemination of the findings to education and welfare policymakers. The added value of the ITN consists in promoting a new type of governance of education and welfare that transcends traditional national borders. It will develop a theoretically advanced, empirically measurable and internationally comparable conception of edu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'DNA damage response and genome stability: The role of ATM, ATR and the Mre11 complex' (AAMDDR).

assistant: **Concept**

Chromosomal DNA is continuously subjected to exogenous and endogenous damaging insults. In the presence of DNA damage cells activate a multi-faceted checkpoint response that delays cell cycle progression and promotes DNA repair. Failures in this response lead to genomic instability, the main feature of cancer cells. Several cancer-prone human syndromes including the Ataxia teleangiectasia (A-T), the A-T Like Disorder (ATLD) and the Seckel Syndrome reflect defects in the specific genes of the DNA damage response such as ATM, MRE11 and ATR. DNA damage response pathways are poorly understood at biochemical level in vertebrate organisms. We have established a cell-free system based on Xenopus laevis egg extract to study molecular events underlying DNA damage response. This is the first in vitro system that recapitulates different aspects of the DNA damage response in vertebrates. Using this system we propose to study the biochemistry of the ATM, ATR and the Mre11 complex dependent DNA damage response. In particular we will: 1) Dissect the signal transduction pathway that senses DNA damage and promotes cell cycle arrest and DNA damage repair; 2) Analyze at molecular level the role of ATM, ATR, Mre11 in chromosomal DNA replication and mitosis during normal and stressful conditions; 3) Identify substrates of the ATM and ATR dependent DNA damage response using an innovative screening procedure.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how ''Dead End': An Economic and Cultural History of Japan in the Age of the Great Depression, 1927-1937' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The project presents an economic history and socio-cultural reconstruction of Japan in the age of the great depression; it is an attempt to demonstrate the depression's 'total' or multicontextual implications by outlining different but complimentary views of what was defined as the depression's core problems (and their possible solutions) within different social classes and within different strands of thought. Seen in historical perspective, it covers the period from the 'ShMwa financial crisis' (1927) until the outbreak of the second Sino-Japanese War (1937). The project consists out of three components: First, it addresses the macro-economic ideas in vogue at the time. It specifically concentrates on the personalities and roles of finance ministers Inoue Junnosuke  K© and especially Takahashi Korekiyo ØK/ ('Japan's Keynes'), who has widely been credited for smoothening the role of the global depression on the Japanese economy. The second part of the project rests with the origins of depression in Japan's official and semi-official colonies in 1927 and the role the latter played in fueling the later crisis on the Japanese mainland. The project investigates the role of speculation, and inquires to which degree the effects of depression were 'imported' from the subsidiary economies of Taiwan, the Korean peninsula, and Manchuria. Third, as this project has a strong focus on the role economic realities were identified ('semantics'), it also develops a cultural history of the age of depression. The project identifies the rise of a new vocabulary and discourse in an era obsessed with the idea of an economic and moral dead end (ikizumari).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Data Integrated Supply Chain Optimisation' (DISCO), addressing dissemination and exploitation.

assistant: **Impact**

The objective of this project is to commercialise ‘Valuechain.com’ which is a scalable cloud-based platform that enables manufacturing businesses to optimise overall supply chain performance by connecting with supply chain partners, capturing and analysing real-time structured and unstructured data from internal and external sources, and providing multiple scenario plans to optimise individual company and overall supply chain performance through predictive analytics.Valuechain.com is a disruptive technology and will catalyse the creation of new SME business models in high value manufacturing sectors, unlocking the potential of vertical and horizontal integrated networks of businesses that could not previously collaborate effectively as the information exchange between businesses was very fragmented and manually executed.Combining real-time knowledge of the supply chain with predictive analytics will provide unprecedented visibility and decision support for manufacturing supply chains and enable European manufacturing companies to monitor and mitigate supply chain risk, create dynamic collaborative supply chain networks by streamlining operations and reduce waste to improve global competitiveness. The four key performance measures that will be used to assess current supply chain performance and the beneficial impact of valuechain.com on European Manufacturing SME competitiveness are as follows:- Customer service - Overall Equipment Effectiveness- Cost of Inventory- Supply Chain CostsThis project will enable Valuechain.com to build on its existing commercialised supply chain collaboration and mapping solutions and secure first mover advantage.The average annual revenue generated from license rental model and aggregated procurement commissions from each client is €1,200 an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'High algal recovery using a Salsnes Water to Algae Treatment (SWAT) filter technology'.

assistant: **Concept**

Microalgae has been researched and cultivated commercially for human and animal nutrition, for cosmetics and pharmaceutical applications, for biofuels and biomass production, for wastewater treatment and to some extent for greenhouse gas abatement. The production for the microalgal biomass market today alone generates a turnover of 1.25 billion US$ per year (0.94 billion €/yr) while the total algal world market is about 7-7.5 billion US$ per year (5.2-5.7 billion €/yr) and is growing, with European Union being home to 30% of this world’s algae market activity.The most critical challenge faced by all algae growers is harvesting. Harvesting is expensive and energy intensive. A group of European SMEs (Salsnes, Asio and Inwatec) has decided to work together to capture a part of the global algae harvesting equipment market. The objective is to develop a universal algae harvesting technology by building on their experiences gained from removing particles from wastewater and by modifying wastewater treatment technologies to harvest algae. Salsnes Water to Algae Treatment (SWAT) technology will use a flocculator followed by a Salsnes Filter to harvest algae. Two RTDs (Aquateam and HERI) will carry out research and development to achieve the objective. Two test sites have been chosen (IGV in Germany and Aqualia in Spain) to test the SWAT technology.The SWAT technology will result in 95% algae recovery, 40% lower costs than the best state of the art technologies (Centrifuge and Dissolved Air Flotation) and energy consumption < 0.08 kWh/m3 of algae. The consortium will explore the SWAT technology in the growing biofuel market (which has a projection of 1.6 billion US$ or 1.2 billion Euros by 2015) and then in other algae markets.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Evaluating Economic Policy Instruments for Sustainable Water Management in Europe'.

assistant: **Objectives**

Economic policy instruments (EPI) have received widespread attention over the last three decades, and have increasingly been implemented to achieve environmental policy objectives. However, whereas EPI have been successfully applied in some policy domains (such as climate, energy and air quality), their application to tackle water management issues (drought/water scarcity, floods, water quality control) are beset by many practical difficulties. EPI-Water sets to assess the effectiveness and the efficiency of Economic Policy Instruments in achieving water policy goals, and to identify the preconditions under which they complement or perform better than alternative (e.g. regulatory or voluntary) policy instruments.Using a common multi-dimensional assessment framework, the project will compare the performance of single economic instruments or their apposite combinations with the performance otherwise achievable with regulatory (command & control) interventions (such as water restriction/rationing, licensing or permitting), persuasive instruments or voluntary commitments.Furthermore the project will identify remaining research and methodological issues that need to be addressed, in particular with regards to the further development and use of national accounting, for supporting the design, implementation and evaluation of EPI in the field of water management.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'In-situ automated monitoring of trace metal speciation in estuaries and coastal zones in relation with the biogeochemical processes (IMTEC)' (IMTEC) under Fifth Framework.

assistant: **Objectives**

Coastal ecosystems are threatened by anthropogenic activities and in particular by chemical pollution. Assessment of the impact of chemical pollutants are presently very difficult, because their speciation, i.e. the distribution of the various chemical forms of a given compound, cannot be determined accurately enough or at a sufficiently high time frequency. Development of the novel Multi Physical-Chemical Profiler (MPCP) will provide a unique analytical tool allowing automated trace metal speciation measurements coupled to master variables. Real-time monitoring, as well as detailed temporal/spatial evolution of the distribution of chemical species, will enable us to develop much better predictive models based on biogeochemical processes, to evaluate the impact of human activity on the ecosystem, and therefore to optimise industrial/social developments. The MPCP will also be applicable as early warning system in response of discharge events.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Remote-Activated Delivery of Therapeutic Exosomes (RADoTE) via an Injectable PEG Hydrogel Carrier'.

assistant: **Objectives**

As a Marie Skłodowska-Curie Fellow, I will develop and demonstrate remote-activated delivery of biological therapeutics loaded into an injectable hydrogel, where delivery is triggered by applying near-infrared (NIR) light that safely and non-invasively penetrates deep into living tissues. The hydrogel carrier will be designed to deliver and stabilize cell-derived exosomes and microvesicles, together referred to as extracellular vesicles (EVs), which have recently gained attention for their ability to effectively deliver biological information and cargo directly to target cells. Developing sophisticated delivery systems for EVs will streamline their translation to clinical application, enabling the huge potential for this novel biological therapeutic to be fully realized. This system will be advantageous in simultaneously providing localized delivery, enhanced EV stability, and crucially, externally triggered release. This project will provide the first demonstration of localized and controlled delivery of EVs, with the added novelty of an externally NIR-triggered delivery system. By combining my expertise in designer hydrogel chemistry, the supervision of Prof. Molly Stevens at Imperial College London (ICL) who runs a world-class interdisciplinary biomaterials-focused group, and a secondment with The Technology Partnership (TTP) specializing in technology translation, this project is ideally situated to deliver the highest quality results.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Noah Labs Vox - Detecting Worsening Heart Failure with AI-based Voice Monitoring' (2021-2027).

assistant: **Innovation**

Heart failure (HF) is a chronic and life-threatening disease that impairs the heart's ability to pump blood, leading to high hospital admission rates and substantial costs for health systems globally. Managing HF is challenging due to the rapid deterioration of patients, leading to decompensation and hospitalization. Effective HF management aims to avoid hospitalizations through frequent monitoring and timely medication adjustments, as up to 64% of HF hospitalizations are avoidable.The existing HF monitoring methods—manual weight monitoring, telemonitoring programs, cardiac implants, and pulmonary arterial pressure devices—are inadequate. They fail to reduce hospitalization rates on a large scale, either due to imprecision, delayed detection of worsening HF, or invasive nature. As a consequence, HF patients face high re-hospitalization rates (83% hospitalized within five years), reduced life expectancy (≈50% die within five years), high costs (≈€25K), and low quality of life due to frequent hospitalizations. Healthcare providers struggle with the high-cost burden (exceeds €100Bn/year), inability to conduct timely monitoring, and lack of scalable solutions.Noah Labs introduces NL Vox, a novel patented Digital Medical Device (DMD) revolutionizing heart failure (HF) management. Utilizing AI-based voice monitoring for the first time, NL Vox detects HF decompensation up to 21 days before conventional methods, offering accurate, early worsening HF detection comparable to invasive solutions. This enables timely medication adjustments, potentially reducing HF-related hospitalizations by 30%, HF-related mortality rates by 30%, and healthcare costs by more than 30%.The objective of the EIC project is to enhance our AI model and obtain regulatory approval for market entry. Additio