RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Le' Colaz: Building an Adaptable Future Brick by Brick through A Comprehensive Framework for Circular, Secure, and AI-Optimized Sustainable Construction', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The Le’ Colaz system redefines construction and renovation by integrating innovative tools, products, and techniques to enable adaptable, circular, and sustainable building practices. Inspired by “LEGO bricks,” its modular framework combines bio-based and recycled materials with advanced snap-fit components, designed for seamless assembly, disassembly, and reuse. This approach significantly improves the adaptability of buildings and building units to new uses, ensuring optimal utilization of indoor spaces and enhancing living and working conditions. By embedding principles of circular economy and life-cycle optimization, Le’Colaz extends the service life of buildings and increases the reuse and recycling of building elements, reducing waste and resource consumption. The system incorporates two cutting-edge digital platforms: the Internet of Materials Module (IoM²), which uses IoT sensors and digital product passports to monitor component performance, enabling predictive maintenance and informed decisions on reuse or recycling, and the Internet of Building Brain (IoB²), powered by Large Language Models (LLMs), which optimizes renovations, regional component reuse, and compliance with regulatory frameworks. Together, these tools facilitate dynamic adaptations to changing user needs and environmental conditions while promoting best practices for design for adaptability, reuse, and deconstruction. The system’s effectiveness is validated through simulation-based assessments and Living Labs in Athens and Trondheim, demonstrating measurable gains in energy efficiency, circularity, and adaptability. By fostering awareness and innovation in sustainable construction, Le’ Colaz sets a new standard for circular, resource-efficient buildings. Through its modular design, digital inte
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Spatial Analysis of Rural Development Measures' (SPARD) targeting Seventh Framework.

assistant: **Abstract**

The aim of the SPARD project is to develop a modelling tool that will help policy-makers to understand the causal relationships between rural development measures and their results in a spatial dimension. Based on spatial-econometric analysis it will include ex-post evaluation options and the extension to ex-ante assessment with the purpose of giving support to the planning of targeted RD policies, programmes and measures. The project will compile a well-structured database, to organise both indicators from the Common Monitoring and Evaluation Framework (CMEF), distinguishing input, output, result, impact and baseline indicators, and other data specifically used by the RD management authorities in the Member States (MS), and extrapolate missing indicator values. This requires a procedure to standardize the utilisation of results amongst users at different levels. The emphasis of the project will be the development of an analytical framework that considers characteristics and needs of target areas and target groups. The key task of the project is to develop a quantitative model, using spatial econometric modelling. This will allow the identification of causal relationships of RD policy implementation. In this manner the cost-effectiveness of RDPs can be analysed in their spatial dimension. Evaluations/ assessments of selected policies and measures and their impacts will be made at the EU-27 scale. Furthermore it shall be demonstrated that the methodology is feasible at different scales of application and levels of data aggregation. Validation of the modelling framework will be carried out in 5 case study regions. The end product of SPARD will be a multiple-option and variable-scale DSS tool capable for use in horizontal and vertical evaluations. As a collaborative projec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Pseudo-Riemannian Geometry: holonomy groups, homogeneous spaces, and foliations' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

This project focuses on global pseudo-Riemannian geometry, i.e. geometry of manifolds with a non-degenerate, but indefinite, metric. The aim is to investigate, and if possible classify, global special" pseudo-Riemannian geometries, in particular: (1) pseudo-Riemannian manifolds with a special holonomy group, (2) homogeneous (in particular symmetric) pseudo-Riemannian spaces, (3) foliated manifolds with a homogeneous transverse pseudo-Riemannian geometry, or with totally geodesic leaves. The main first task is (1), with focusing at first on the Lorentzian case. The point is the case where the holonomy group is not semi-simple. The three points are linked. For example, understanding (1) is helpful for (2), (2) may provide examples for (1), a work on (3) (totally geodesic leaves) may help to classify (1) in low dimension... They are also related to physical problems.To achieve the goal, several techniques are to be used, some which I know, many which I have to learn. For (1), local differential calculus, Cartan-Kahler theory, foliations, techniques developed by Galaev (analytic germs). For (2), classical Lie group theory, and techniques newly developed by Kath, Olbrich, Neukirchner (twofold extensions...). For (3), (G,X)-structures... I wish to work on those subjects with Helga Baums team in Berlin, Humboldt Universitat. The idea is that we have close interests, but with different, complementary approaches and competencies.That is why: - this transnational cooperation is likely to produce good results (all the more, in a subject that requires, simultaneously, several competencies), - it fits the objectives of this action, as it will complete and diversify my skills and give me an expertise in the field of and special pseudo-Riemannian geometries."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'MULTIMEDIA PUBLISHING INFORMATION ENGINE' under Fourth Framework.

assistant: **Concept**

The purpose of MEDFORM is to provide advanced facilities to publishers for the swift production of multimedia books and compact disc titles for fields like education. It is further intended to satisfy the consumer need for user-friendly information retrieval from such publications. The project will facilitate management and integration of multimedia material, such as text, images, sound and video, also providing support for production-related content specification, application structuring and execution strategies. Analysis of the publisher organization model is expected to cut the cost of title production, distribution and similar activities.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Potential strategies for reducing particulate emissions during dry machining' to be submitted under Fourth Framework.

assistant: **Abstract**

The use of cooling lubricants in metal cutting operations is coming under incre asingly critical scrutiny in manufacturing companies. In 1996, for example, the volume of lubricant (water miscible and water immiscible) requiring disposal, totalled 580.125 t (tonnes) /BfW 96/ in Germany alone. The cost of disposal flu ctuated, depending on the degree of contamination, between 80 ECU/m3 and 1500 E CU/m3 in Germany. Additionally, investigations have revealed that 30% of all se rious skin diseases in the metal working sector are attributable to the use of lubricants /BG 93/. Possible solutions to these problems range from the optimis ation of the use of lubricant through strategies to minimise the quantity of lu bricant, to total abandonment of the use of media of this nature in dry machini ng operations. Dry machining operations, particularly those performed on bri ttle materials, cause dust like particles to be released. In contrast to wet ma chining operations, these particles are not picked up by the lubricant and carr ied away but can spread out freely from the point at which they originated. In terms of Safety at Work, these emissions represent a significant health risk. I n addition to the effects on the human body, which range from nuisance to cance r, adequate account must be taken of the danger of dust explosions and fires. E xploratory investigations show that peak concentrations of up to 400 mg/m3 (ins ide the amchine) can occur when casting materials are milled (material machined : GG25). However, the maximum permissible limit for inert metallic dust which h as not been classified as hazardous is currently 4 mg/m3 (inhalable proportion outside the machine) /MAK 97/. It is essential, therefore, to implement proc ess measures involving both the process and the mac
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Probing the relativistic jet composition in high energy active galactic nuclei' (HE-COSMIC-SOURCES), addressing dissemination and exploitation.

assistant: **Impact**

The proposed project aims at probing the relativistic particle content of the most numerous, persistent population of high energy cosmic sources in the Universe: jets of active galactic nuclei (AGN). This undertaking is leveraged by today's synergy of high performance ground- and space-based photon detecting instruments as well as key advances in astroparticle physics experiments, yielding dense high quality data over a broad energy range from a large collection of AGN. Such powerful objects are among the prime candidate sources of the enigmatic ultrahigh energy cosmic rays, however, conclusive evidence is still missing. The development of diagnostic tools that probe the composition of the material in AGN jets, that go beyond the so far used broadband modeling methodology, is key to this project, and allows a systematic search for observational features of hadronic interactions from high energy cosmic jet sources. Meaningful constraints on their relativistic particle content will have far-reaching implications for the physics of cosmic rays, particle acceleration to energies beyond reach for any terrestrial laboratory, and our physical understanding of jet formation, collimation and mass loading. Furthermore, significant impact for searches of extragalactic neutrino sources is expected. This project will promote the professional reintegration of the proposer, who has a strong background in broadband modeling including hadronic processes, into the European astroparticle physics community, will complement the activities of the center of experimental astroparticle physics at Innsbruck University, and strengthen the scientific return of neutrino astrophysics experiments with its strong presence in Europe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'European Advanced Superconductivity Innovation and Training' (EASITrain), addressing dissemination and exploitation.

assistant: **Impact**

The two greatest obstacles to a wide spread adoption of superconductivity remain the limited understanding of its fundamental principles and the yet insufficient capability for large-scale, cost-effective deployment of the technology. Science rather than serendipity is the key to unlock the potentials of this alluring natural phenomenon. The proposed ITN integrates sound research projects aimed at learning to predict the behaviour of superconducting materials, at introducing innovative manufacturing techniques, at developing efficient cryogenic refrigeration techniques as key enablers for future applications and establishing these technologies as the new state of the art. The ambitious goals of this consortium are (1) making advanced superconductors fitter for the market, (2) assessing their innovation capacities and (3) equipping a new generation of researchers with the unique skills required to convert knowledge into products: Efficient grid power management, 21st century medical imaging, leaps in effectiveness of wind power generators, efficient electric propulsion systems and sustainable refrigeration for industry give an impression of the potential societal benefits that superconductor-based technologies can catalyze. This initiative under European leadership federates leading universities, research centres and industries, embracing a variety of science sectors, such as physics and mathematics, material sciences, process and mechanical engineering, refrigeration, cryogenics and innovation management. The intriguing blend of science and engineering, compounded by visionary application opportunities in companies, creates a fertile environment for innovative training of early-stage researchers. Significant training lead-times call for a dedicated action. This ITN will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Rapid Magnetic Blood Filtration for the Treatment of Sepsis: a Feasibility Study' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

This project will look at a novel method of treating sepsis, one of the world’s leading causes of death. The method uses magnetic nanoparticles (MNPs) that bind to specific entities in blood, combined with MediSieve's patented magnetic blood filter. By infusing the MNPs into an extra-corporeal blood loop containing the filter, MediSieve can remove both the pathogens that cause sepsis (bacteria) and the endotoxins that are responsible for the dysregulated immune response which is characteristic of sepsis. Importantly the method would work even in antibiotic resistant cases.Annually, there are 1M cases in the US and 900K in Europe, with 135K deaths/year in the EU. Mortality rates are 29-50% with a cost of €25K per patient. With the aging of global populations sepsis incidence is increasing rapidly (8-13% annually in the decade to 2013).The challenge is that both the pathogens and the immune response contribute to the disease. The destruction of bacteria by the immune system or antibiotics creates large quantities of endotoxins, which in turn aggravate the immune response and cause a cascade towards septic shock. MNPs that bind specifically to gram-negative bacteria and endotoxins enable the two targets to be rapidly and safely removed from circulation using MediSieve’s magnetic filter. The method provides the unique capability to specifically target both root causes of sepsis, reduce both the mortality and the economic costs of sepsis.The objectives of this Phase 1 study are to validate the technical and commercial feasibility of the proposed treatment method. The latter includes detailed market research, business planning, healthcare economics modelling and a detailed investment proposal with timelines and return on investment projections. The technical assessment will i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Biomedical Technology for Respiration Analysis through Optoelectronics' (1994-1998).

assistant: **Concept**

The recent developments in image processing and parallel computing make the analysis of the movements of any number of points on the chest wall both possible and practical. It is therefore now possible to obtain a quantitative and detailed image of the complex movements involved in respiration. This allows either a better understanding of respiration physiology and pathologicalbehaviours or new perspectives for diagnosis, prognosis and therapeutic treatments. The image processing procedures implemented by a parallel architecture provide the necessary accuracy. The proposed method allows the three-dimensional (3-D) analysis of the displacements of any number of points on the chest wall and abdomen. Thus, through a specially designed model, the trunk volume variations during respiration and various manoeuvres (tidal volume, deep breathing, vital capacity, etc.) and its splitting into different compartments of physiopathological interest like horizontal sections (upper thorax, lower thorax and abdomen) and vertical ones (right and left) can be estimated. This approach is completely non-invasive and non-ionising; the 3-D movements of several body landmarks of the thorax, abdomen and back, are tracked by an automatic image processor connected to a computer. The subject is completely free to move and the analysis can be performed in different postures (upright, sitting and supine) and for long periods of time. Since the proposed method provides a direct measurement of the volumes in a three-dimensional reference frame, it can be used without a subject specific calibration. The technical validation of the method 'per se' has been already fully performed and the feasibility of this project has been proved by the results already obtained [Ferrigno et al., 1994]. Starting from th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Senescence as a key factor in leukemogenesis and bone marrow homeostasis in aging'.

assistant: **Objectives**

Cancer is a major public health problem and one of the leading causes of death worldwide. In particular, it has been the second cause of death in Spain, Europe and United States. Although cancer can occur at any age, aging is one of the main risk factors for its development. Aging is a complex scarcely understood multi-step process associated with the gradual functional decline of organs and systems. In addition, age-dependent changes in epigenetic regulation occur, indicating that epigenetic regulation may also play an important role in aging. Similar changes have been observed at the cellular level in a mechanism known as senescence. This mechanism is a cellular response that limits the proliferation of aged or damaged cells, behaving as a tumor suppressor mechanism and transformation events lead to escape from it.Chronic lymphocytic leukemia and acute myeloid leukemia are the most frequent types of leukemias and have median ages at diagnosis of 68 years. Both have a low incidence in the young population and increase with age. Thus, it is important to explore novel approaches to understand the mechanisms of aging favoring these types of leukemias, thereby unraveling new target molecules for treatment and prevention. We propose to explore the senescence epigenetic profile in leukemic cells, the impact of senolytic drugs in patients and in the development of AML in spontaneous animal model. The approach will bridge cancer epigenetics with senescence, aging and leukemogenesis.This proposal will augment my scientific knowledge and practical skills. In addition, the complementary planned activities of the action will provide me to the additional tools to become an independent investigator in the near future.


**Keywords:** Senescence, Leukemogenesis, CLL, AML, hematopoies