RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Mediterranean overturning circulation' (MEDOC), addressing dissemination and exploitation.

assistant: **Impact**

The air-sea interactions and the interior mixing are key processes of the global oceanic meridional overturning circulation and in setting the properties (temperature, salinity, chemical concentration) of water masses. Such processes are only crudely parameterized in global ocean models and coupled climate models due to their relatively coarse resolution and the lack of physical understanding of the mixing processes. Due to its unique geometry; to its relatively small size and to its similarities with the global overturning circulation, the Mediterranean Sea offers the possibility to better comprehend the role of mixing processes. Moreover, the substantial changes observed in the Mediterranean water mass properties, in particular the formation of a new warmer and saltier type of deep water in the western Mediterranean Sea, have shown that anomalous surface events cant impact on the deepest layers of the Mediterranean Sea over very short time scales. To understand the future evolution of the anomalous water masses, their impact on the Mediterranean Overturning Circulation and ecosystems, it is critical to better comprehend mixing processes. The aim of this proposal is to provide new insights on the role of mixing processes in the Mediterranean Overturning Circulation. We will investigate the combined role of surface mixing due to air-sea induced and interior mixing in setting the Mediterranean thermohaline structure, by applying a consistent theoretical framework based on the inclusion of air-sea fluxes in the recently developed tracer-contour inverse method. Further more, the results of the tracer-contour inverse method will be combined with nutrients climatological fields to calculate nutrient fluxes and to identify sources and sinks. The outcome of this work will lead
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Mobile OpportunisTic Traffic Offloading' (MOTO).

assistant: **Innovation**

To support the booming demand in mobile 4G data services, the MOTO project proposes to design, dimension, implement, and evaluate a new network architecture in support of dynamic traffic offloading strategies to relieve a congested 4G/LTE network. Going far beyond present infrastructure based offloading approaches, MOTO explores an additional layer of disruptive offloading protocols that make use of direct terminal-to-terminal communications.<br/>MOTO definitely takes an operator point of view to opportunistic networking by keeping terminal based offloading under the control of the operator's infrastructure. It explores and evaluates distributed offloading control protocols, it investigates coordination strategies between mobile and broadband Internet operators, it designs and implements a distributed trust and security policy, it derives formal capacity enhancements estimates and works toward understanding mobility and contact opportunities.<br/>MOTO adopts an experimental methodology, providing enhancements to an open source simulation environment, and carrying out practical experimentations on an operator's large scale integrated testbed for architecture and protocol validation. The operators' vision, requirements, and experience are backed by a strong team of experts in wireless networking technologies both from academia and industry.<br/>Thanks to MOTO offloading solutions, the operators will decide how much bandwidth to allocate for supporting crowds of users sharing data hungry services in a flexible and efficient way, and will be able to handle peaks of traffic without overprovisioning the infrastructure and without blocking the service to its users.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Apelin inhibition as an anti-cancer therapy'.

assistant: **Innovation**

The spread of cancer is a major cause of mortality and morbidity throughout Europe and beyond. As the growth of solid tumours is dependent on the formation of a neovascular supply, inhibition of tumour-induced neoangiogenesis represents an actively pursued strategy to treat human cancers. Current anti-angiogenic therapies are, however, hampered by the onset of resistance through upregulation of additional angiogenesis factors. Therefore, the identification and study of these alternative neo-angiogenesis regulators as therapeutic targets is currently of key interest. Apelin is a potent angiogenic factor frequently found upregulated in cancer. However, the in vivo pathophysiological relevance of apelin function in cancer has not been addressed so far.In this proposal, we intend to study apelin inhibition and function in spontaneous cancer models. We will take a multidisciplinary and entirely in vivo approach that will combine the power of mouse genetics with state-of-the-art analysis techniques. We will evaluate in parallel the function of apelin in cancer and the highly promising effectiveness of apelin inhibition as a therapeutic cancer target either alone or in a combined anti-angiogenesis therapy.The relevance of de novo formation of lymphatic vessels in the progression of cancer has only recently been recognized. Using state-of-the-art techniques we will extend our studies by not only assessing the in vivo role of apelin in angiogenesis but also its involvement in lymphangiogenesis. Taken together, we believe that this project will shed new light on the role and function of a novel factor that regulates vessel formation in cancer and validate its potential as therapeutic target. If successful, our in vivo multidisciplinary study will open a new avenue for the treatme
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Computationally driven discovery of organic dyes for photoredox catalysis from physicochemical principles and mechanistic information' (ORGhvCAT).

assistant: **Concept**

Photoredox catalysis has become a quintessential part of organic synthesis and gained wide interest in the chemical industry as a mild and robust synthetic methodology. Acridinium salts are a prominent substitute for transition metal-based photocatalysts (PCs) due to the modularity of the core, which makes them and structurally related dyes an optimal platform for structure-property tuning. However, a limited understanding of how structure influences reactivity prevents rational design, while the synthetically realizable chemical space is far too vast to explore using even high-throughput experimental methods.The objective of the proposed action is to study computationally the elementary mechanistic steps integral to photoredox catalysis to establish how they are each influenced by PC structure. We will develop an automated workflow for high-throughput computational molecular PC construction and analysis, in which known molecular fragments are coupled together by chemically precedented steps. Finally, Bayesian optimization will be used to guide the machine learning model building. This is distinct from conventional approaches in the field as we aim to increase the quality of our model with mechanistic understanding from quantum chemical calculation. My expertise in the fields of synthetic, physical, and computational organic chemistry, provide me the necessary skillset and ability to learn new concepts and successfully execute this project. The gained knowledge and results from the project will be an asset and help to build sustainable processes in the chemical industry in EU. The work will be implemented in the research groups of Prof. Robert Paton and Prof. Jeremy Harvey, with a secondment period in the group of Prof. Abigail Doyle. The investigators’ combined experti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'CustomerServiceAI: Fully language-independent AI platform for automated and augmented customer service' to be submitted under Horizon 2020.

assistant: **Abstract**

Customer service is a huge industry: €720BN in Europe alone, growing 9% a year.  It is also very labour-intensive: over 14M Europeans, 70% of them women, work as customer service agents. And it has immense economic impact: poor customer service costs US businesses $1.6TN every year. In our digital era consumers demand immediate answers; and businesses and public sector are under huge pressure to deliver quality service more cost-efficiently. Artificial intelligence (AI) promises automation, but quality is poor, damaging customer experience. In addition, most development is done only for English, with US companies dominating the market. CustomerServiceAI (CSAI) is a fully language-independent AI platform for customer service in Chat, Email and Social. Built upon our proprietary deep neural network architecture and clustering algorithms, it can take unstructured customer service databases in any language and automatically cluster them to find the different ways people ask questions. It has a unique Human+AI approach: it Augments agent work, Automates repetitive cases, and Analyses what people ask for actionable insights. CSAI is also disruptive in its cost-efficiency. It can be deployed in days vs. months required by competing solutions, and at less than 20% of the cost. Our 28 customers, incl. Zalando, Telia and Finnair, and our partners, incl. SAP and Salesforce, are proof of the value our innovation brings. Our core team of 23 experts has built a multi-award winning technology, with revenues of €1.1M in 2019 and €1.1M in Seed funding raised from Germany’s largest VC.In this Phase 2 project we will develop the next version of CSAI, which will be significantly more scalable. We will improve our core algorithms, develop a customer dashboard with self-service and analytics
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Unlocking the Hidden Treasures of Aquatic Extremophiles: sustainable development of industrially relevant novel active biomolecules.'.

assistant: **Concept**

Extreme aquatic environments account with a vast and yet largely unexplored biodiversity that holds immense potential for novel active biomolecules with multiple industrial applications. However, the harsh and challenging conditions such as accessibility, environmental hazards, ineffective or inaccurate sampling techniques, and poor bioprospecting pose significant obstacles to their exploration and sampling. Overcoming these challenges is crucial for unlocking the potential of extremophiles to benefit society. The EXPLORA project will depart from two extreme aquatic ecosystems selected such as the acidic Rio Tinto in Spain and the psychrophilic Antarctic Region. By developing innovative, accurate, and sustainable tailor-made sampling methods, employing cutting-edge bioprospecting techniques, and utilising state-of-the-art analytical tools for isolation of bioactive substances, in the EXPLORA project it is expected to find and isolate microorganisms which produce novel antimicrobial and antioxidants compounds, sialylated extracellular polymeric substances and, plastic-degrading acidophilic enzymes which applicability will be validated for pharmaceutical, cosmetic, nutraceutical, and for PET recycling purposes, respectively. Additionally, deeper understanding on the legal frameworks in the planned contexts such as the Nagoya Protocol and Antarctic Treaty Legal Requirements is also envisaged. By achieving these objectives, EXPLORA will contribute to the sustainable exploration of biodiversity hotspot regions, advancing the development of next-generation sampling methods, expanding bioprospecting from the screening for new chemicals into biological function, and contributing to the understanding of potential trade-offs inherent in the exploitation of ocean and other aquatic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Dynamic Droplet Size Control in Unmanned Aerial Spraying Systems for Balancing Drift Risk and Spray Quality' (UASS-DDSC).

assistant: **Concept**

Unmanned Aerial Spraying Systems (UASS) are rapidly expanding in global agriculture, yet spray drift remains a major constraint, particularly under strict regulatory frameworks such as those in the EU. The key challenge is the inherent trade-off between spray quality and drift reduction: fine droplets provide better coverage but are highly drift-prone, while coarse droplets reduce drift but compromise deposition uniformity. This project proposes a dynamic droplet size control strategy to resolve this contradiction. Within a single spraying mission, the system will apply fine droplets in upwind areas to secure target coverage, and switch to coarser droplets when approaching field boundaries to mitigate drift risk.The objectives will be achieved by combining engineering design, physical and data-driven modeling, and agronomic validation. A coupled model linking droplet size, drift distance, and environmental parameters will be developed, embedded into a variable droplet spray system, and validated through both semi-controlled and multi-factor field trials. This integrated approach will ensure scientific robustness and practical feasibility. The project is hosted by the Universitat Politècnica de Catalunya (UPC, Spain) under the supervision of Prof. Emilio Gil, with co-supervision from Dr. Jean-Paul Douzals at INRAE (France). UPC contributes expertise in engineering-based pesticide application and European standardization, while INRAE provides the artificial wind wall platform for drift evaluation.The expected outcome is a validated strategy that achieves a dynamic balance between spray coverage and drift reduction, achieving up to 20% drift reduction in field trials. This directly supports the objectives of the Directive 2009/128/EC on the Sustainable Use of Plant Protect
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Awareness and resilience through European multi sensor system' to be submitted under Horizon Europe.

assistant: **Abstract**

Public awareness to environmental risk is key for building resilient societies. ArtEmis will develop a smart sensor system, monitoring radon, temperature, acidity and other observables in groundwater in real time. The ground-breaking sensor design will assure affordability, resilience and low power consumption optimizing life cycle management. The project aims to produce 100-200 sensors, that will be deployed in sensitive sites in collaboration with municipalities. Changes in radon concentration have the potential to serve as precursor for earthquakes and volcano eruptions. To advance our knowledge in this field we propose the development of a cheap sensor system, that can be employed on a large scale in earthquake prone areas of Europe. The real time collected data is used to build machine learning (ML) models for the analysis. The collected and AI processed data will generate a real time map of hydrological and geochemical changes that is shared to the scientific community and public bodies engaged in the project. A pilot project engaging citizens of the participating municipalities is part of the dissemination and exploitation activities. We expect artEmis to clarify the longstanding issue of earthquake predictions by means of geochemical precursors like changes in radon concentration. The system is designed for scalability. Dissemination and exploitation activities are tailormade to ensure support and expansion of artEmis after the project’s completion.  Radon content in water causes health issues and artEmis offers a novel way to monitor both content of radon as well as changes in real time that may indicate changes in flow pattern. Hence, artEmis is facilitating multi-purpose use of the sensor system. The project will result in a shift of paradigm for environmenta
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Evolution of VEnom Regulation', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Animal venom is a remarkable example of convergent evolutionary novelty - it has independently evolved across all phyla of the animal kingdom to subdue prey and predators. To produce and deliver this potent biochemical weapon, venomous animals possess specialized anatomical structures which emerge from different developmental tissues in the various lineages. How animals have repeatedly evolved this key adaptive trait is unknown. The recent omics revolution has generated an explosion of venom-gland transcriptomes mainly for biodiscovery. However, the mechanisms underlying the emergence and regulatory evolution of venom have not been investigated. In this ambitious and ground-breaking project, I will use a hierarchical approach and large-scale comparative transcriptomic analyses to shed light on the following open questions: Q1) To what extent is the independent evolution of novel adaptive traits associated with convergence in transcriptome evolution? Q2) Which molecular processes contribute to the evolution of these innovative traits? Q3) To what extent does the expression pattern of new specialized cell types overlap the original tissue from which they develop? I will answer Q1 by comparing non-homologous venom-gland transcriptomes across the major lineages of the animal kingdom. I will answer Q2 by focusing on one lineage (Neogastropoda) and comparing the venom-gland with homologous, non-venomous organs. Finally, I will answer Q3 by analysing gene expression patterns between structurally and functionally different cell types within the venom-gland. The success of this project is ensured by the integration in top hosting bioinformatics groups at the Université de Lausanne and collaboration with leading experts in cone snail evolution. This project will provide intensive
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The application of integrated biosensors with antibody and macrocyclic receptor libraries in the measurement of algal cells and toxins in water' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

The objective of the proposed work is to develop biosensor systems for the reliable monitoring of algae toxins and cells. Diagnosis will also be carried out using newly developed immunotoxicity assay.  The use of an integrated electronic sensing principle is a very flexible approach, allowing the sample to be probed in many ways. The proposed approach is to use simple, disposable electrochemical affinity sensors. Affinity sensors are based on a receptor molecule specifically recognizing and binding an analyte. This is a very sensitive method and for biosensors the receptor most commonly used is an antibody. Recently a number of chemically or biochemically derived artificial receptors have been developed and their use in the construction of sensors has led to a new class of biomimetic sensors. The principle of producing immunosensors has been demonstrated for other applications and is considered to have a high chance of success.  Two state-of-the-art approaches are proposed for the production of receptor molecules. This is clearly a difficult task, but one which we believe will be successful. The proposers have considerable experience in antibody production, and significant experience in combinatorial synthesis. Both approaches have been demonstrated for use with compounds which are not dissimilar to those considered for this project. These approaches have the added advantage that they can be adapted to ariy group of compounds.  The biosensor array will be combined with multivariate analysis software for use in analyzing real samples taken from a number of sites throughout Europe. The instruments will be compared with current laboratory based methods such as chromatography.  Immunotoxicity assay method will also be developed. The toxic and nontoxic algae will be fed to b