RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Population genetics of transposable elements in drosophila. Molecular studies of te's that show fixation or high frequencies' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Research objectives and content Theoretical models show that transposable element (TE's) insertions at individual genomic sites are expected at lowfrequency as a result of an equilibrium between transpositional increase in element abundance and one or more opposing forces. High frequencies or fixation are expected only if element insertions have functional significance to their hosts. In Drosophila, the technique of in situ hybridization on the polytene chromosomes permits identification of sites occupied by TE's in chromosomes isolated from natural populations. The data on D. melanogaster unequivocally shows that the frequency of occupation of a given chromosomal site by a member of a particular family is nearly always very low. There is only a handful of exceptions, which form the subject of this proposal.  l Objectives: 1- To determine whether (1) these apparently fixed insertions involve individual nucleotide sites or (2) reflect insertions at different locations within the same band. In situ hybridization permits the localisation of the insertions in terms of chromosome bands, being necessary a molecular approach in order to discriminate between this two alternative hypothesis.  2- If (1) is the case, to determine the causes of high element frequencies or fixation at an unique site. Molecular characterization of the insertion site will shed a light on the evolutionary forces that drove this insertions to high frequency or fixation . Training content (objective, benefit and expected impact)  Objective: to improve my training in the following subjects: Molecular biology techniques: DNA handling, in situ and dot-blot hybridization, southern blotting, DNA cloning, PCR, DNA sequencing.  Other methods: DNA sequence analysis. Theoretical population genetics training: The
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Cogo - all ride in one app. Cogo gathers electric shared bikes, scooters, cars and mopeds from 250 mobility operators in more than 700 cities, and is now ready to launch the full-service platform.'.

assistant: **Concept**

Bibi Blomqvist co-founder and COO of Cogo ApS. Cogo is an app that gathers shared rides for frictionless mobility and a better tomorrow. In Cogo you can find more than 250 mobility operators of shared bikes, scooters, cars and mopeds and can be used in more than 700 cities worldwide. I founded Cogo back in March 2020 during the pandemic, with two old colleagues from the management group of momondo, later KAYAK part of Booking Holdings. We founded Cogo with a mission to move people away from short private car trips and on to shared mobility, to help create more sustainable cities. My driver for starting Cogo is that traffic in our cities and the derived CO2 emissions are one of the biggest challenges we need to solve in our lifetime. The industry of shared mobility has come to a stage where the complexity and fragmentation is ready for an aggregator level to reach the full potential shared mobility can offer. To create a successful aggregator that has the perfect combination of best user content, product users love and the right business model is my niche expertise. During this programme we launch and roll-out Cogo full-service platform where users can start, stop, pay and manage all trips across multiple shared mobility operators within the Cogo app. Cogo is currently pre-revenue and will with the launch of the full-service platform start to generate revenue. This project will set-up and execute on a clear strategic and technical roll-out playbook from launch in our home market to roll-out throughout Europe. We will set-up and establish the technical platform to scale quickly yet controlled with Cogo Console for multi-partner operational control including a well-thought through complex revenue management system and strategy to maximise shared mobility utilisation while
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Computational understanding of multiple images'.

assistant: **Objectives**

Automated 3D measurement and model building are key technologies for precision engineering. Digital photogrammetry -3D measurement from sequences of digital `photographs' - has many advantages over competing technologies: it is non-invasive, fast, and allows very large working volumes, the equipment is inexpensive, robust, portable and easy to use, and there is a strong potential for full automation. European companies -including the two industrial partners of CUMULI - are world leaders in this rapidly evolving field. However, strategic research is needed to further enhance the automation and flexibility of their products.Key areas include:- More complex scene primitives (lines, circles, facets\ldots) - current systems measure only isolated points.- Robust extraction and tracking of primitives through multiple images.- Ability to incorporate and reason with known geometric constraints: matching constraints between structure in several images; camera calibration (when available); and known 3D structure (coplanarity, known angles or distances\ldots).- Improved statistical modelling and computational schemes.There has recently been an intense and very fruitful wave of research on these and related aspects of multi-image perception, lead by the European computer vision community. The academic partners of CUMULI were actively involved in the Esprit projects BRA VIVA and REALISE, which lead to a significant improvement in our understanding of the geometry and invariants of multiple views, and techniques for reasoning with them. CUMULI aims to capitalise on this basic research, refining and extending existing results on multi-image geometry and reasoning, and converting them to valuable industrial know-how.Approach- Extend and refine current results on multiple image geometry
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Platform for animation and virtual reality'.

assistant: **Concept**

We propose to address the common needs of animation and virtual reality - Young researchers involved with network partners will obtain experience systems, by developing a comprehensive software platform consisting of of the international breadth of their field of research, major facilities drawn from our various partners uniquely broad experience. - We will exchange both post-doctoral and more senior research workers, as The proposed software platform will have as its objectives: appropriate * to provide to the animator facilities for automatic creation of animation - For younger research workers the main goal of the placements will be training. We collectively offer a very broad range of topics. Placements * to provide facilities for controlling or guiding virtual moving objects by speaking in a microphone like a choreographer would do for conducting will be made with a view to evening out the skills base across the whole a ballet dancer  network. Some sites have identified graduate-level courses which could be included. * to offer motion synthesis with: biomechanical models, physics- based modelling, state feedback control, optimisation, identification and - For more senior research workers the goals in placement are more varied. learning - The network will enable the strengthening and formalisation of existing * to extract 3D objects cleanly from photographs and video sequences contacts between partners, to general benefit. * to extract motion parameters from magnetic motion capture - Some sites have close close contact with industry. Here work will * to help animators with the task of managing the large number of images include industry-driven sub-projects which will enable visitors to develop in real production environments contacts with industries in other countri
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'European frozen tumour tissue bank' to be submitted under Fifth Framework.

assistant: **Abstract**

Elucidation of the complete human DNA sequence and unprecedented breakthroughs in genomics, proteomics and bio-informatics will identify critical molecular targets that can be applied in cancer prevention, diagnosis and therapy. Translation of results of basic research into the clinic will be greatly enhanced by a supra-national European bank of human frozen tumour samples, linked with large clinical trials such as conducted in EORTC. This proposal plans a network of frozen tumour sample collections, processed and stored according to standardised protocols, in major European cancer centres and universities. The virtual tumour bank, a database containing digital microscopic images and coded-linked patient data, can be searched by the whole European scientific community. A European code of conduct will be developed for use of tissues based on the various legal and ethical regulations as well as incentives and rules for contributers.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Stability and change in sound patterns of the world's languages: typological, physiological, and cognitive factors""' (SCSPL).

assistant: **Innovation**

The goal of the current proposal is to provide a new empirical foundation to our knowledge of sound patterns that are statistically underrepresented (typologically rare) in the world's languages. Typologically rare patterns have been claimed to be more difficult to produce and perceive, and more prone to undergo sound change. Yet this claim is controversial: others maintain that due to the stabilizing force of grammar and learning, within a language, all sound patterns are equally entrenched. Understanding the status and the origins of typologically rare patterns remains one of the most profound challenges in linguistics, phonetics, as much as in psychology and cognitive science. There is, however, an insufficient empirical knowledge of the status of typologically rare patterns in languages that have stabilized these patterns in their synchronic grammars. Whether typologically rare phonotactic patterns can be shown to be relatively less entrenched within a speaker's grammar is an open empirical question and will be the major research focus of this proposal. Based on several languages (Germanic, Slavic, Kartvelian) the current proposal investigates how the licensing of typologically rare phonotactic patterns (reverse sonority clusters, syllabic consonants) interacts with language particular characteristics of articulatory implementation (the coordination of articulator motion in space and time). The detailed production studies are complemented by imitation experiments that allow us to assess whether typologically rare patterns show greater plasticity through language use. The results will make a significant contribution to our understanding of the perception-production link in speech, language typology and sound change, and the reciprocal relationship between cognitive a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Probing Europe’s Undiscovered Genome: A Metagenomics Approach to Find Unique Enzymes for the Biofuel and Bioprocessing Industries' (2007-2013) under Seventh Framework.

assistant: **Objectives**

Our civilization is facing increasing pressures on finite natural resources, and Europe in particular faces serious challenges to its energy security. The purpose of the project is to explore Europe’s unique environments to discover novel enzymes which may support the development of viable bioenergy and other bioprocessing industries. Hydrogen has great potential as a future energy source. To make biological hydrogen production more favorable and competitive, more powerful hydrogenases needs to be discovered. Various kinds of enzymes such as lipases and cellulases are used as biocatalysts for a variety of bioprocessing industries; however there is still a strong need for new generations of these enzymes with more favorable characteristics such as stability to extremes of temperature, pressure, and pH. In this research, a metagenomics approach will be used to target the discovery of novel enzymes by exploring the world of unknown microorganisms in Europe. Finally, to fully achieve the goal of creating more powerful enzymes, directed evolution approaches will be applied. The anticipated result of this research is to discover highly effective hydrogenases, cellulases, and lipases. This project aims to provide tremendous environmental, economic, and strategic benefits and improve the quality of human life. The enzymes discovered may have a big influence and increase the competitiveness of Europe. The specific objectives of this research are to: (1) create metagenomic libraries using genomic DNA isolated directly from European water and soil samples (2) using activity based agar plate screening, discover novel hydrogenases, cellulases, and lipases (3) isolate and identify the sequences of the enzymes and clone novel ones into an expression host strain (4) explore their poten
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Memory Engram Maintenance and Expression'.

assistant: **Objectives**

The goal of this project is to understand how specific memory engrams are physically stored in the brain. Connectionist theories of memory storage have guided research into the neuroscience of memory for over a half century, but have received little direct proof due to experimental limitations. The major confound that has limited direct testing of such theories has been an inability to identify the cells and circuits that store specific memories. Memory engram technology, which allows the tagging and in vivo manipulation of specific engram cells, has recently allowed us to overcome this empirical limitation and has revolutionised the way memory can be studied in rodent models. Based on our research it is now known that sparse populations of hippocampal neurons that were active during a defined learning experience are both sufficient and necessary for retrieval of specific contextual memories. More recently we have established that hippocampal engram cells preferentially synapse directly onto postsynaptic engram cells. This “engram cell connectivity” could provide the neurobiological substrate for the storage of multimodal memories through a distributed engram circuit. However it is currently unknown whether engram cell connectivity itself is important for memory function. The proposed integrative neuroscience project will employ inter-disciplinary methods to directly probe the importance of engram cell connectivity for memory retrieval, storage, and encoding. The outcomes will directly inform a novel and comprehensive neurobiological model of memory engram storage.


**Keywords:** engram, memory, integrative, connectivity, optogenetics, learning, retrieval, recall, connection
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Ultimate growth characterization for development of new semiconductor technologies' (USEMITE).

assistant: **Innovation**

The integration of III-As structures with Silicon is of major importance to industry. Currently nanostructures are already being applied to information and communication technologies and their integration with Silicon electronics is being developed. Current fabrication techniques allow patterning of nanostructures from bulk layers but modify the properties of the materials by introducing defects. The ability to control nucleation and growth of self-assembled quantum nanostructures will propel the development of electronics and photonics. The combination of in-situ Low Energy Electron Microscopy (LEEM) during Molecular Beam Epitaxy (MBE) offers the possibility to directly observe the growth on real-time in real and reciprocal space. Therefore, to observe the nucleation dynamics, the lattice structure dynamics, surface dynamics, etc. The level of control that LEEM can provide to MBE is unheard of and unique.The goals of the MSCA project are: • Elevate current III-V LEEM system to enable direct interaction with MBE facilities, both research and industry based, across Europe.• Apply the technique to the fabrication of site-controlled nanostructures.• Transfer the growth conditions found during direct observations of the growth by MBE-LEEM to industrial fabrication of quantum devices.During the MSCA period, the LEEM-MBE will be used to study the nucleation of GaAs on Si, the nucleation of InAs QDs on GaAs, nucleation of InAs QDs on complex structures to induce site control nucleation using strain field, nucleation and growth of nanowires (NWs) using catalysts and self assembled. Additionally an aluminium anodization system will be fabricated and installed in order to deposit the catalyst in a hexagonal lattice along the area of the whole substrate. The latter project will be
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'New Molecular and Cell-based Approaches to assess Food Astringency and Bitterness'.

assistant: **Concept**

Taste properties are vital to humans: they impact human survival, nutrition, health and well-being. The problem of unpleasant taste properties, namely bitter- or astringent-tasting compounds is emerging in many diverse research fields. Beyond the obvious interest in food science, nutrition, and in the improvement/selection of crops, also human taste disorders and drug discovery domains could also benefit from research on astringency and bitterness. Crossing the boundaries among different fields, BeTASTy goes beyond the current state-of-the-art of food-oriented researches to respond to the prominent challenges on astringency and bitterness. This proposal will provide an in-depth mechanistic and functional understanding into the MAIN PHYSICAL-CHEMICAL EVENTS triggering the physiological and neural perception of astringency by an innovative approach considering the main oral key pieces namely salivary proteins, epithelia and emphasizing the role of mechanoreceptors on that sensation. BeTASTy will also unveil how, for some compounds, astringency and bitterness CAN GO TOGETHER by an innovative all-in-one model. Additionally, the individual features that account for sensory differences will be deepened by a pioneering approach based on human organoids and electroencephalography. The final goal, will be the creation of cutting-edge CELL-FREE BIOSENSORS based on the identified orally active mechano- and bitter taste receptors to assess astringency and bitterness respectively, and by overcoming the main drawbacks of the existing (cell-based) ones. Endowed with a truly differentiated and disruptive character, this groundbreaking project will engage food chemistry, biochemistry, neuroscience, sensory analysis and biotechnology fields of research to outdo the state-of-the-art. Only