RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Tom PIT Studio - platform for designing information systems' (2014-2020).

assistant: **Concept**

Pharmaceutical sector demands information systems (IS) to be custom designed and in compliance with Good manufacturing practice (GMP)  regulative. In addition IS must be build according to Food and Drug Administration (FDA) regulative CFR Part 11 . This is currently a big problem for all IS providers which are cooperating with pharmaceutical sector because the effort made to achieve this is substantial, time consuming and expensive. The price of such validated system can be three times as high as with similar non-validated system. We can attribute this to programming methods which are not agile enough. With the proposed project we want to introduce, first to EU and then global markets, an innovative solution to address above mentioned challenges - Tom PIT Studio (TPS). TPS introduces unique modeling method of developing IS which reduces development time by 70% and lowers maintenance cost by 90%. Demand for such a product comes from all pharmaceutical companies with a potential in other industries as well. Product is therefore not limited to local (EU) market but has is a great global potential (Asia, USA) estimated at 7 billion €. Product is developed to TRL6 level and is already being used for demonstrational purposes as well as evaluation with SME and pharmaceutical companies in our geographical region. Plan is to develop product to TRL 9 and assure fast market up take. Feasibility study is critical for us to further elaborate commercialization strategy in order to access global market. TPS is a great business opportunity for us but also has bigger impact on EU economy as it provides leverage for SME IT companies to enter market currently controlled by big IT vendors with their own competitive solution thereby widening offer of information systems and consequently low
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Light as a signal for nonchemical cell-to-cell communication in synthetic and biological cell communities' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Engineering cell-to-cell communication is fundamental –yet highly challenging– for programming multicellular systems and interfacing living and biomimetic synthetic cells. The problem lies in developing specific communication that is independent of existing chemical signaling and in connecting it to cell behavior. Both the high complexity of intercellular signaling in living cells and the fairly limited capabilities of synthetic cells severely restrict possibilities to engineer communication in and between these two realms. Here, I propose a new nonchemical mode of cell-to-cell communication that operates with light as a signal. I aim to develop sender cells that produce visible light as a signal that corresponding receiver cells respond to. In this light-based communication, the signal will propagate at the speed of light independent of diffusion, will cross optically transparent barriers without the need for membrane transporters, and will allow communication even between physically separated cells. Also, the light signal will be orthogonal of native chemical signals, resulting in high specificity and no cross talk. First, I will establish light-based communication in molecularly defined synthetic cells to decipher the central rules of this new mode of communication. Detailed characterization (light generation, response, distance, dynamics, orthogonality) of light-based communication will provide the framework for later programming of multicellular behavior. Second, I will transplant light-based communication into bacterial and mammalian cells, showing for the first time that communication with light is possible at the cellular level. Last, I will engineer diverse communities of living and synthetic cells with light-based communication showing various behavior, includ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Preparing Land and Ocean Take Up from Sentinel-3' in the context of a Seventh Framework call.

assistant: **Objectives**

The objective of the LOTUS project is to support the development of GMES by developing applications of Sentinel-3 to complete the space observation infrastructure that are designed for land and ocean monitoring for GMES. Sentinel-3 is the GMES space component for monitoring the oceans. The SRAL instrument onboard Sentinel-3 is a radar altimeter that will provide observations of sea-surface and land-ice topography, in continuation of altimeter missions such as ENVISAT, Jason-1 and Jason-2. Furthermore, the SRAL instrument will operate in a SAR mode and provide along-track high-resolution heights of the sea surface in the open oceans, in the coastal seas, in-land water and sea ice areas. The SAR capability is a new feature and no data products based on this SAR mode data are provided or used operationally. New methodologies and new data processing chains need to be developed to prepare the take-up of the GMES Sentinel-3 data.The LOTUS project will develop new methodologies, data processing chains, and applications of the SAR mode data for the high resolution sea surface heights, wave heights and wind speeds in the open oceans, coastal seas as well as in sea ice covered regions for operational marine services. For the operational land services, the LOTUS project will develop new methodologies, data processing chains, and applications of the SAR mode data for the in-land water levels in rivers and lakes, soil moisture, and snow depths. In turn, the new products based on the SAR mode data will support operational services for emergency response and security in the events of, e.g., storm surges and flooding. The new land products will provide valuable information about the hydrological cycle and support services on monitoring hydrological parameters for climate change. Throug
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Endoderm specification in xenopus and zebrafish - the role of the transcription factors gata4,5 and 6' (1994-1998).

assistant: **Concept**

Research objectives and content During vertebrate development gastrulation leads to the formation of three germlayers, the ectoderm, mesoderm and endoderm. So far very little is known about the differentiation of the endoderm, the germ layer giving rise to the 1ining of the gut and associated organs like liver and pancreas as well as the lining of the lungs. There is strong evidence that transcription factors of the GATA family are functionally involved in endoderm specification. The Drosophila gene serpent, which is essential for normal patterning of the gut is a homologue of the GATA family and targeted mutation of mouse GATA4 has been shown to block visceral endoderm formation. In zebrafish GATA5 and 6 are expressed in cells fated to be endoderm prior to gastrulation, Very recent results demonstrate that ectopically expressed GATA5 induces an endodermal marker gene in Xenopus animal cap explants. In the proposed project the function of GATA4, 5 and 6 in endoderm formation will be analyzed. Therefore the background knowledge and use of explants in the frog Xenopus laevis will be exploited as well as the availability of mutants in zebrafish. The expression pattern of GATA4, 5 and 6 will be characterized with respect to the well known cell fates in Xenopus. More importantly GATA4, 5 and 6 will be used as early molecular markers to investigate the signalling pathways that give rise to endoderm. Zebrafish mutants will be analyzed for early effects on endoderm formation and GATA-expression. By ectopic expression of GATA family members, and use of their dominant negative forms in Xenopus and zebrafish the function of these factors in endoderm specification will be analyzed. The designed experiments will improve the currently poor understanding of endoderm formation in verte
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Academia-Industry Pathway to Quick Linux'.

assistant: **Concept**

The Academia-Industry Pathway, Path2QuickLinux, develops knowledge and transforms practice to accelerate progress toward a European information society (i2010). Path2QuickLinux is a partnership and pathway between Cran (UK) and EXAGroup (Spain), based on a common research project and aiming to increase skills exchange between the two sectors. Cran is the technology originator and provider. An SME, EXAGroup, will contribute to the richness and diversity of the applications and implementations that it will facilitate. In the Path2QuickLinux project, we will implement NFS’s alternative protocols (accelerated NFS or a-NFS) by incorporating the developed parallel-streamed g-Jet engine to accelerate the file sharing traffic. With the accelerated and secure a-NFS that remain fully compatible with the existing IT infrastructures, computer users can open and share remote files (such as vi, Emacs, MySQL, OpenOffice Writer/Impress/Calc, MPlayer, Firefox and Google Earth) on the Internet without having to install new software, upgrade to any new platform or change the way they work. Path2QuickLinux is believed to meet the immediate needs and is positioned to adapt to the needs of i2010 through the minor versioning of the existing data communication protocols. The resulting software will be strengthening the competitiveness of the EC-led software worldwide. The introduction of selected results from the Path2QuickLinux Project to University BSc/MSc curricula and professional training courses will also prepare the next generation of skilled scientist/engineers in EU ensuring continuity after the funding period is over.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Explosion Models Evaluation Project' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

The objective of the project is to clearly evaluate and document the current status of consequence models relevant to vapour cloud explosions and to further develop the understanding of the response of equipment and structures to explosions. This will provide confidence in assessing risks and designing/protecting against such hazards. Vapour cloud explosions and resulting damage to equipment and structures represent a serious threat to escalating an initial incident into a potential disaster with resulting damage to life and the environment. The use of simulation models provides information to assess hazards and to ensure appropriate mitigation systems and measures are used or implemented to reduce the risk of major industrial processes. To assess the consequences of a vapour cloud explosion it is necessary to consider the vapour cloud explosions themselves (Project Theme VCE), the resulting net loading received by equipment and structures (Project Theme RL), and the mechanical integrity of equipment and structures (Project Theme SR). The objective of the project will be achieved through the following activities: 1. identify on a European basis the extent and availability of explosion consequence models; 2. develop a model evaluation protocol relating to each of the three project themes; 3. agree and document test cases that permit the evaluation of models relating to three project themes; 4. carry out an evaluation of available models based on the protocols and test cases developed under activities 1 and 2 above in the three areas; 5. identify any area of deficiency or concern; 6. produce a full and clear report on the conclusions of the project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Study of Ion Migration in Perovskite Solar Cells via X-ray Photoemission Spectroscopy Imaging and Photoluminescence Microscopy' under Horizon Europe.

assistant: **Concept**

Organic-inorganic hybrid perovskite solar cells (PSCs) attract enormous attention in the field of emerging photovoltaics due to their unique optoelectronic properties and unprecedented advances in performance.  In just over a decade, the power conversion efficiency of PSCs has increased from 3.9% to 25.5%, suggesting this technology might be ready for large-scale exploitation in industrial applications.  However, stability and scalability are some of the major concerns that impede the commercialisation of PSCs. Among these, exploring strategies to enhance the long-term stability of PSCs is a main research topic in the perovskite community. While it is generally considered that ionic defect states in the perovskite layer such as vacancies, interstitial sites, anti-site substitutions as well as surface and grain boundary defects inevitably lead to the degradation of PSCs,  much remains unknown about the fundamental nature of ionic defects and in particular their migration in perovskite materials. This project will focus on the study of ion migration by a unique combination of electrical and spectroscopic methods which will allow tracking changes in both the compositional and optoelectronic properties of perovskites with the same spatial resolution and thus directly linking the migration of ionic species to their effect on material properties. By applying this novel methodology, I will explore the effects of perovskite composition, film microstructure and mitigation strategies on the ion migration and investigate how ion migration impacts the stability of perovskite materials. This project will significantly expand our current understanding of ion migration in PSCs and provide valuable insights for enhancing device stability.


**Keywords:** Perovskite, Stability, Ion Migr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'DEmonstration of LIdar based Clear Air Turbulence detection'.

assistant: **Concept**

Atmospheric turbulence encounters are the leading cause of injuries to passengers and crews in non-fatal airline accident. The number of turbulence accidents has been growing by a factor of 5 since 1980. A whole class of turbulence (Clear Air Turbulence), representing 40% of turbulence accidents, cannot be detected by any existing equipment including state-of-the-art weather radar. Operational concepts for the protection against turbulence hazard, based on a UV LIDAR, are: - Short-range measurement of air speed ahead of the aircraft and action on the flight controls, - Medium-range detection of turbulence, and securing of passengers by seat belts fasten. The short-range concept has been validated in the frame of the FP5 AWIATOR project. The objective of DELICAT is to validate the medium range turbulence detection (based on backscattered energy fluctuations). In development phase, both short and medium range will be integrated in single equipment. The validation of medium range turbulence detection is based on the comparison of LIDAR data and aircraft sensors data. - A UV LIDAR mock up is designed, manufactured and flight-tested, - The LIDAR data and the aircraft sensors data are compared off line for the same atmosphere area. The consortium assembled for the DELICAT project includes all the expertise necessary to reach the objective, and will take advantage of previous projects such as FP5 AWIATOR and FP6 FLYSAFE. The project resources are globally adapted to the project ambitious objectives and innovation content. DELICAT takes advantage of existing hardware (laser sub assemblies, test aircraft fairing) to achieve the goal at lower possible cost. The DELICAT project will directly contribute to the objectives of the AAT.2008.3.3.2. topic by increasing customer safety; t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Sustainable Company'.

assistant: **Concept**

This proposal aims at providing new inter- and multidisciplinary solutions to the challenges of sustainable corporate behaviour through the analysis of ‘best practices’ of ‘highly sustainable companies’, by using the experience of ‘green public procurement’ in Catalunya as an example of how to successfully implement ‘sustainable’ concerns. The implementation of the research findings into the university curricula shall contribute to solidifying the sustainable business model by internalizing such concerns by the future business officers and lawyers. A three-stage process is envisaged to achieve the formulation of sustainable policy: in the first stage, ‘green public procurement’ practices will be analysed to provide examples of successful business model change sustainability. The conditions of public tenders portray the societal expectations and needs at the public level, and the corporations serving these needs serve as an example of a successful change towards sustainability. In the second stage, corporate ‘best practices’ will be analyzed as an example of profitably sustainable behaviour and as a foundation for change in currently non-sustainable companies. Recommendations for the EU legislator will be formulated as to how sustainability could be implemented at the EU corporate law policy level. At the final stage, the research findings will be incorporated into the classical legal and economic university curricula, to close the gap between classical legal and microeconomic theories and the demands for sustainable development. As such development represents one of the main EU goals, accounting for approximately 60% of the Horizon 2020 budget, this research aids the pursuit of new economic foundations, considering the importance of multinational corporations for the ac
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Telomere dysfunction and aneuploidy'.

assistant: **Objectives**

The major hallmarks of almost all cancers are aneuploidy, deregulation of the cell cycle and the reactivation of telomerase. While telomerase expression as been widely shown to ensure chromosomal stability, telomere dysfunction can be made responsible for aneuploidies universally found in cancers.   Aneuploidy develops early in tumour development while telomere dysfunction is mostly found at the end of cellular life span and might induce aneuploidy directly when checkpoint functions at the end of the life span are abrogated. This proposal addresses how the last cell cycle transitions are monitored by the cell cycle checkpoints and how loss over control of these may lead to aneuploidy.   We are proposing to study the DNA damage response in normal cells that have one or more short telomeres at replicative senescence and to elucidate whether different threshold levels trigger different responses. Furthermore we propose to study the chromosomal changes in cells that have abrogated checkpoints at replicative senescence and analyze if a common tetraploidy intermediate promotes the elimination of genes that suppress cell growth and amplifies those that are associated with growth advantage, including telomerase. Our major goal is to better understand the relationship between short telomeres and the induction of genomic instability that leads to carcinogenesis.