RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'PROtotype Demonstration Using low-cost Catalysts for Electrolysis to H2' (PRODUCE-H2) targeting Horizon 2020.

assistant: **Abstract**

Hydrogen (H2) generated from renewable energies, such as solar and wind, and water has a huge potential as a carbon-free energy vector which can be exploited on demand through fuel cell technologies. Proton-exchange membrane electrolysers (PEMEL) are a mature technology that can be coupled with intermittent renewable power sources. However their wide deployment still depends on innovative breakthroughs regarding the design of alternative catalysts avoiding the use of precious metals and fulfilling three main characteristics: sustainability, cost-effectiveness and stability.In the “PhotocatH2ode” ERC Frontier Research Starting Grant (consolidator stream), we explored a coordination polymer structure for amorphous molybdenum sulfide (a-MoSx), refined the understanding of its catalytic mechanism (Artero and coll., Nature material 2016) and developed strategies to remedy reductive corrosion issues that so far limited the implementation of such earth-abundant H2 evolution catalysts in PEMEL. We aim at exploiting these new findings in PRODUCE-H2, an ERC Proof of Concept project which proposes to (1) optimize the formulation of these catalytic materials and assemble them in polymer-membranes, (2) assessing their performance and quantifying their stability during long-term tests performed under realistic operating conditions, (3) upscaling their production thanks to a newly developed synthetic process and (4) implementing them in a noble-metal-free PEMEL prototype. PRODUCE-H2 will exploit pre-existing and newly created intellectual property with the aim of proposing a cost-effective industrial solution for PV-coupled on-site hydrogen production. This project will be in close collaboration with Toyota Motor Europe who have been selling fuel cell cars since 2015.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'A Native Mass Spectrometry Systemic View  of Cellular Structural Biology' (SystemDirectMS) targeting Horizon Europe.

assistant: **Abstract**

Protein structure and consequently function is influenced by the cellular content. The array of splice variants, post-translational modifications, cleavages and the ability to bind cofactors and drugs, is governed by the surrounding cellular milieu. This is determined by internal and external cues such as cell type, developmental stage, stress conditions, disease and aging, which give rise to an ensemble of distinct protein entities. To study this diversity, there is a need for methods that enable structural studies under “close-to-life” conditions, maintaining the natural environment and biological diversity, features that are often lost during biochemical purifications. Our recent discovery that native MS can be conducted within crude cellular lysates (direct-MS), while preserving the biological context, offers many new experimental avenues for investigating protein interactions and diversity. Here, we propose to take native MS to a new dimension: enabling a systemic view of cellular structure biology by endorsing technological, computational and methodological developments. To do this we will: (i) Establish a platform for high-throughput screening of protein interactions. (ii) Unravel protein interactions in human and other eukaryotic cells; (iii) Develop a method for whole-organ direct-MS analysis, unravelling the tissue-specific proteoform landscape. Each of our three independent but complementary aims involves a different biological system, going from bacteria through human cells to intact tissues. Together, these advances, in conjunction with the high-resolution and sensitivity afforded by current mass spectrometers, has the potential to advance a plethora of fields, including cell biology, pharmacology and biotechnology. Overall, we anticipate this project will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Testing the multi-component model of human cognitive abilities' in the context of a Seventh Framework call.

assistant: **Objectives**

What causes people to differ in their mental abilities? The most replicated result in the study of individual differences is that people who perform better on one kind of mental ability test tend to perform better on other kinds of tests as well. After more than a century of research there is still no scientific consensus on the reasons of this phenomenon.The existence of a general mental ability that permeates any human intellectual activity has been proposed, but this hypothesis does not sit well with findings in cognitive psychology and neuroscience. In his PhD thesis, the Applicant has provided an alternative account, which has been further developed in collaboration with a researcher from Princeton University. This account, the multi-component model of human intelligence (MCM), postulates that all mental tasks tap a vast array of different psychological processes.One of the main reasons behind a century of disagreement on the nature of mental abilities is the separation of what has been called the two disciplines of scientific psychology: experimental and differential. The former is concerned with universal characteristics of human cognition, whereas the latter attempts to explain the causes of variation in mental abilities.The MCM provides a model of individual differences that stems from contemporary advances in experimental cognitive psychology and neuroscience. Yet, in order to yield a theory that overcomes the separation of the two disciplines, it still has to provide a measurement model for differential psychology as well as a mathematical model of test performance based on modern test theory. The primary aim of the project is to develop these models and test them, along with a specific prediction of the theory, on already available large-scale data sets usin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Multifunctional landscapes: towards an analytical frame work for sustainability assessment of agriculture and forestry in europe' (MULTILAND), addressing dissemination and exploitation.

assistant: **Impact**

The notion of multifunctionality employmed in the spatial system of landscapes may build a powerful basis for an analytical framework for a sustainability impact assessment of land use strategies related to agriculture, fishery and forestry in Europe. A precondition for such a framework is a proper analysis of three levels of investigation, namely:1) the complete inventory of landscape functions;2) the analysis of mutual interdependencies of the various environmental, social and economic functions, and;3) the implementation of methods to balance interests an achieve consensus between conflicting demands. Besides an overview of different scientific approaches to address the concept of multifunctionality, the proposed study will systematically screen research requirements related to the three levels of investigation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Calcium-Sensing Receptor (CaSR): Therapeutics for Non-Communicable Diseases', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The calcium sensing receptor (CaSR) is a class C Gprotein-coupled receptor that plays a pivotal role in systemic calcium metabolism by regulating parathyroid hormone secretion and urinary Ca excretion. Abnormal CaSR function is implicated in calciotropic disorders, and in non-calciotropic disorders such as Alzheimer’s disease (AD), cardiovascular disease (CVD), diabetes (DM), sarcopenia and cancer, which account for >25% of the global disease burden. The CaSR is a unique GPCR whose principal physiological ligand is the Ca2+ ion; it is expressed almost ubiquitously; interacts with multiple Gα subtypes regulating highly divergent downstream signalling pathways, depending on the cellular context. The CaSR Biomedicine is a fully translational project that utilises the concept of a single molecule, the CaSR, influencing a range of physiological and disease processes, to develop a unique, strong multidisciplinary and intersectoral scientific training programme preparing 14 young scientists to become specialists in GPCR biology and signalling.The objectives of CaSR Biomedicine are:1. Educate and train Early Stage Researchers to become highly innovative scientists to enhance their career perspective. 2. Elucidate ligand- and tissue-dependent differences in CaSR physiology by examining its functions at cellular level and thus to contribute to the understanding of GPCR signalling in general; 3. Assess how CaSR function is altered in AD, CVD, DM, sarcopenia, and cancer, and to find innovative CaSR-based therapeutic approaches for these major, age-related disorders.4. Establish long-lasting interdisciplinary and intersectoral cooperation among researchers and between researchers and industry, to strengthen the European Research Area.Therefore the CaSR Biomedicine will investigate t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'EXPLORING AND EDUCATING CULTURAL LITERACY THROUGH ART', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The overall aim of EXPECT_art is to identify current barriers and potentials for promoting critical cultural literacy by means of arts education, education through arts and uses of arts in education within and across different educational contexts in Europe, to generate and activate knowledge on how to enhance critical cultural literacy and understanding among European citizens. The objectives of the project are:1.Identification of existing measures and barriers for critical cultural literacy in arts education, education through arts and uses of arts in education at the national and local levels through secondary data analysis and the study of existing practices through fieldwork2.Exploration of the impacts and potentials of decolonization of arts education, education through arts and uses of arts in education to foster critical cultural literacy, by conducting in-depth case studies of schools and local communities in six countries applying critical ethnography and community-based research in Art Exploratoriums3.Development and dissemination of interventions and workshop formats for enhancing critical cultural literacy through formal and informal arts education.EXPECT_Art utilizes an approach to cultural literacy that is informed by critical pedagogy and decolonial theory. This is operationalized by a community-based research design, including art-based methodologies, involving children, teachers and citizens directly as research participants. The research design consists of three interconnected parts: Researcher Art Exploratorium, Community-Based Art Exploratoriums and Cultural Literacy Hubs. The project will be implemented through field research in 12 schools and local communities in Denmark, Germany, Hungary, Poland, Slovenia and Spain and involves research instituti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Phase relations between changes in the late quaternary ocean surface and deep water processes in the north atlantic' to be submitted under Fifth Framework.

assistant: **Abstract**

Natural rapid Late Quaternary temperature variations in the North Atlantic region punctuated the last glacial period and are linked to changes in the North Atlantic thermohaline circulation (THC). Recent evidence suggest that these fluctuations are related to variations in iceberg discharge and the input of melt water to the ocean. Temperature fluctuations have occurred also, but at a lower amplitude, during the Holocene, and will most likely occur in the future. However, the basic forcing mechanisms behind these events are strongly debated. Tracing these triggers is the main objective of the proposed work. For this purpose it is necessary to construct a high resolution record Late Quaternary phase relationships between variations in the surface water conditions and deep water formation, which are the two major components of the North Atlantic's THC. Which changes occurred first and which components contributed to a shift in the strength of the THC? Three major factors have to be taken into account (i) sea surface temperature variations(ii) changes in the iceberg discharge and(iii) variations in the deep water mass intensity. These fluctuations will be reconstructed using an innovative multi-proxy approach, a combination of independent lithic" and "biogenic" proxies. This combination is a powerful approach and new results show that such an approach is a pre-requisite for obtaining reliable paleoclimatic information. The study areas cover a long distance of the NADW pathway. The time span ranges from c.150 kyr BP to the present with a focus on the Holocene, Eemian, Termination II/I, and, more generally, on time intervals with strong insolation (July 60°N) changes. Apart from the paleoclimate emphasis, new insights in the use of different proxy types can be expected which
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'New measurement science for the 21st century food business'.

assistant: **Innovation**

The focus of the measurement science group at Unilever Colworth is to develop and apply new measurement capabilities to help improve the overall quality and safety of Unilever's products. Fellows will be fully integrated into multidisciplinary teams to work on projects supporting one of the three major current objectives :i) Development of non-invasive measurement capabilities to help characterize the composition, dynamics and microstructure generated during the processing and storage of foods through to their impact on the human body.ii) Exploitation of DNA arraying technology to explore new applications in human, plant and microbial genomics, reflecting Unilever's interests in Foods.iii) Strategic development of measurement science capabilities to support the work of Unilever's global centre for Safety and Environmental Assurance (SEAC) which is based at Colworth. The group has considerable experience of hosting and training graduates and postgraduates from many cultural backgrounds and Fellows will receive full training in the use of state-of-the-art instrumentation and techniques (e.g. MRI, confocal Raman, genomics) and industrial research project management. They will also have the opportunity to access complementary expertise in the group's extensive external collaborative network.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Development and application of global lipidomic arrays to inflammatory vascular disease'.

assistant: **Innovation**

How lipids are regulated on a global scale during vascular inflammation is not known.  Thus, a major challenge exists to describe and catalog the total lipidome, in particular enabling the identification of new biologically active lipids, and description of changes. This is analogous to ‘omics’ of DNA, RNA and protein, but instead describing diversity of lipids in tissue samples.  Importantly, this would encompass not only knowns, but also the vast number of unknowns that have not yet been catalogued in any study so far. Here, new systems biology approaches that can be applied to many other diseases or samples, and integrated with transcriptomic or proteomic analyses will be developed. These would be used to characterize the global lipidome during differentiation of immune cells, and in ex vivo samples from genomically-characterized inflammatory vascular disease. I hypothesize that development and application of “global lipidomic arrays” will define how lipids are regulated during vascular cell differentiation and inflammation, will identify new markers, and open up new therapeutic strategies.These aims go beyond the current state of the art, and will be achieved by the following objectives that include novel interdisciplinary concepts and approaches:1.Develop analytical methodologies using Fourier transform mass spectrometry and bioinformatics.2.Develop approaches for structural identification, using high resolution MSn, high sensitivity NMR, and new computational methodologies.3.Define the size and diversity of the mammalian cellular lipidome in human platelets (validation).4.Characterize the global lipidome in (i) monocytes during differentiation from stem /yolk cells to resident, inflammatory or foam cells, (ii) plasma from samples genomically characterized for 14 s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Infrastructure for Measurement of the European Carbon Cycle'.

assistant: **Concept**

The IMECC project aims to build the infrastructure for a coordinated, calibrated, integrated and accessible dataset for characterizing the function of the European terrestrial biosphere.Such an infrastructure is necessary since the critical measurements a re spatially dispersed. Their interpretation, however, relies on precise knowledge of the spatial and temporal structures of measured quantities. Thus the measurements must be of the highest quality and precisely calibrated in order to be useful.They should also be well-planned, that is subject to some coordinated and targeted experimental design and should be accessible to a wide range of researchers. IMECC will deliver these services to the range of measurements within various European projects.As an added benefit, the improved measurements will also be increasingly compatible with the range of global measurements. IMECC will not only provide these services for the life of the project but will aid the development of strategies and techniques to streamline this coordination, into the future.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Interdisciplinary training in systems biology' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

The overall goal of this project is to provide advanced training to early-stage researchers in Systems Biology. Systems Biology uses a combination of experimental and mathematical approaches to achieve a deeper understanding of the function and operation o f pathways, cells, organs and entire organisms. Systems Biology has enormous potential in future medicine and predictable treatment regimes. The field requires a generation of scientists trained in experimental and mathematical/computational biology. This project unlocks resources and expertise from: (1) Goeteborg: Research groups at Goeteborg University and Chalmers University of Technology being part of theNational Research School for Genomics and Bioinformatics". (2) Berlin: The Graduate School "Dynamic s and Evolution of Cellular and Macromolecular Processes" and the "Berlin Centre of Genome Based Bioinformatics", with groups from the Humboldt University Berlin, the Max-Planck Institute for Molecular Genetics plus additional centres. (3) Amsterdam: The R esearch School "BioCentrum Amsterdam", a joint venture of the University of Amsterdam and the Free University of Amsterdam. This EST project relies on the following main activities: (1) Five joint PhD projects, in which students undergo their entire PhD pr ogramme in the project. (2) A programme of twenty shorter stays for PhD students. (3) Joint courses and workshops, which will be a central part of the training, communication, networking and dissemination activities. (4) Opening up ongoing local courses to students enrolled at the different locations. The EST project will contribute to structuring the field of Systems Biology in Europe such that its scientific and socio-economic potential can be used to address important goals of European policies in the he alth