RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Stars: dynamical Processes driving tidal Interactions, Rotation and Evolution' to be submitted under Horizon 2020.

assistant: **Abstract**

The rotational dynamics of stars strongly impacts their evolution and those of their planetary and galactic environment. Space helio- and asteroseismology recently allowed an observational revolution in this domain. They revealed, e.g., that the core of the Sun is close to a uniform rotation while those of subgiant and red giant stars slow down drastically during their evolution. These important results demonstrate that powerful dynamical mechanisms (internal waves, magnetic fields, turbulence) are in action to extract angular momentum all along the evolution of stars.Simultaneously, a very large diversity of stellar systems has been discovered and their number will strongly increase thanks to new space missions (K2, TESS, PLATO). It is thus urgent to progress on our understanding of star-planet and star-star interactions: highly complex dynamical processes leading to tidal dissipation in stars play a key role to shape the orbital architecture of their systems and they may deeply modify their evolution.  To interpret these observational breakthroughs, it is necessary to develop now new frontier theoretical and numerical long-term evolution models of rotating magnetic stars and of their systems. To reach this ambitious objective, the SPIRE project will develop new groundbreaking equations, prescriptions, and scaling laws that describe coherently all dynamical mechanisms that transport angular momentum and drive tidal dissipation in stars using advanced semi-analytical modeling and numerical simulations. They will be implemented in the new generation dynamical stellar evolution code STAREVOL and N-body code ESPER. This will allow us to provide state-of-the-art ab-initio integrated and coupled models for the long-term evolution of stars and of their systems, which cannot b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Capacity building at CIBIO for research using Next-Gen Sequencing' (CIBIO-NEW-GEN), addressing dissemination and exploitation.

assistant: **Impact**

Focus of research in CIBIO is evolutionary biology, conservation genetics, and ecology in a conservation context. A large part of research lines employs the DNA level analysis of biological diversity. During the last years, new technologies arose in this field, which provide today the opportunity to generate new types of datasets with especially high information content for genome based investigation of biological diversity. The proposal of CIBIO has two main objectives: 1) to install new generation sequencing platforms and integrate the respective techniques in CIBIO scientists research, and 2) to equip the unit with the computer infrastructure necessary to handle the increasing amount of data and analytical procedures for downstream sequence analysis and for modeling approaches. This activity will be accompanied by strengthening our research staff and by training and exchange of expertise in collaboration with international partners. The acquisition and implementation of the new technologies and the development of the respective expertise will enable the institution to fully develop its potential in quality of research and international recognition.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Constrained aerosol forcing for improved climate projections' to be submitted under Horizon 2020.

assistant: **Abstract**

The overall objective of FORCeS is to understand and reduce the long-standing uncertainty in anthropogenic aerosol radiative forcing, which is crucial in order to increase confidence in climate projections. These projections are highly relevant for decision makers, as they provide key information on emission pathways that will facilitate the targets of the Paris Agreement to be achieved. FORCeS will identify key processes governing aerosol radiative forcing, as well as climate feedbacks related to aerosols and clouds, and improve the knowledge about these processes by bringing together leading European scientists with trans-disciplinary expertise to i) exploit the wealth of in-situ and remote sensing data that have emerged during the recent decades; ii) perform dedicated laboratory and field experiments; iii) utilize a range of state-of-the-art computational models; and iv) apply novel theoretical methods including machine learning techniques. The process analysis within FORCeS will be conducted with the overall aim of improving a set of leading European climate models, which all provide essential information to climate assessments such as the IPCC report. The gap between knowledge on the process scale and model application on the climate scale is currently a main reason preventing the climate science community to move forward in terms of understanding the role of aerosols and aerosol-cloud interactions in the climate system. FORCeS will bridge this knowledge gap using systematically designed scale chains that involve methodologies for constraining processes on scales ranging from hours to decades, ultimately leading to the desired refinement of model-estimated aerosol forcing and climate sensitivity. FORCeS will reach out to decision makers and stakeholders and provide
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'AI software for the automated detection of covid-19 infection on chest CT' (CoronAI).

assistant: **Concept**

An AI platform to support medical practitioners to screen potential COVID-19 patients using medical imaging.Aidence is creating a new product to automatically analyse chest CT scans and diagnose the presence of corona (covid-19) viral infection. The product receives an image from the CT scanner, analyses it, and returns an easy-to-read report on the most likely diagnosis. This is done in the background fully automatically and the report is available for medical staff within a few minutes. Studies indicate CT is as least as sensitive as the current RT-PCR kit for testing, and is very fast. It is useful in case no kits are available, or when they are inconclusive, and/or radiology staff is unavailable or untrained. This product can be used for triaging as well as longer-term monitoring and early warning for future outbreaks. Because the solution will be operating on all CT chest scans and fully automated, once deployed in hospitals around Europe it will also serve as a case registry for management reporting and tracking of a new potential corona outbreak.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Animal models and drug design for therapy of cancers induced by the oncogene, met', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

Cancer is among the most devastating human diseases and a major aim of the biomedical research is to develop anti-neoplastic molecularly targeted therapies. Receptor tyrosine kinases (RTKs) are pivotal targets for anti-cancer therapies because deregulated RTK signals underlie most events of tumour growth, angiogenesis and metastasis. Strategies to block aberrant RTK signalling involve the development of small chemical compounds that selectively interfere with receptor activation. The RTK Met is a prognostic marker for different carcinomas. Its hyperactivity is thought to be a key event into the development of the invasive/metastatic phenotype of neoplastic cells. The aim of this proposal is to develop Met-specific anticancer drugs. First, a collection of pot ential Met chemical inhibitors will be synthesized and tested for their ability of blocking Met-mediated cell scattering in vitro and activation of its downstream signal transducers. In addition, the first genetically defined animal model of Met-mediated t umour and metastasis will be generated by over-expressing Met only in specific cell types (CRE-mediated recombination). These cells will also express the Luciferase gene allowing non-invasive monitoring of primary tumours and metastasis in vivo. Finally, t his novel mouse strain will be used to optimise the in vivo responses of Met-induced cancers to candidate Met inhibitors. One of the main driving forces of this project is the multi-disciplinary approach undertaken to tackle problems of human health like c ancer. Given the complexity of the cancer biology many researchers with different intellectual and technical skills, ranging from chemical to biology, molecular to in vivo, genetics to pathology will converge. This novel research team will lead this propos al
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Multi-scale model of bacterial cell-cell interactions' to be submitted under Horizon 2020.

assistant: **Abstract**

Transporting selected proteins across the cell envelope in a controlled manner is a fundamental property of all cell types. For bacteria, secretion systems play a central role in the translocation of effectors that mediate interactions with other cells. The bacterial Type VI Secretion (T6S) system is one of the most widespread secretion systems and, in a cell-cell contact-dependent fashion, it injects effectors into eukaryotic and bacterial targets. The T6S system utilizes a cytoplasmic phage tail-like apparatus that is anchored to the cell envelope. A contractile sheath propels a macromolecular effector-loaded tube/spike-complex outside the cell and into the target.Here, we will establish a model of T6S-mediated cell-cell interactions by integrating information from the molecular, cellular and intercellular scales. The model will reveal answers to three paramount questions of the field: Aim 1 (molecular scale) will elucidate an atomic model of the T6S membrane-anchoring complex in loaded and fired conformational states. Aim 2 (cellular scale) will identify the mechanisms and relevance of clustering multiple T6S machines in a confined region of the cell. Aim 3 (intercellular scale) will resolve T6S actively engaged in cell-cell interactions to clarify the in vivo structure and significance of the inner tube in effector translocation and target cell penetration.Electron cryo-tomography (ECT) will be used as the key technique to resolve unique structures in their cellular context, in a native state, in three dimensions and at the crucial nanometer-to-micrometer range. Cryo-focused ion beam milling will be established to prepare samples thin enough for ECT imaging. ECT data will be complemented by high-resolution structural information of sub-complexes (in vitro) and low-r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'AI-BASED BROKERING TECHNOLOGY PLATFORM TO FIND THE PERFECT MATCH BETWEEN THE CUSTOMER AND BANK' in the context of a Horizon 2020 call.

assistant: **Objectives**

For consumers, it is laborious and time-consuming to find and compare loan providers. Without the comparison, customers waste money and gain less beneficial terms of contract with the non-optimal bank. LVS Brokers is a fintech company that has developed an AI-based brokering technology platform and provides brokering services in the financial industry, e.g. to banks and lenders. Brokering service finds the perfect match between the customer and bank. The innovative AI-based LVS platform develops itself based on previous and new decisions and is scalable to other areas and all languages. The unique AI-based technology digitalises and automatises the work that competitors perform mainly manually. Proof-of-concept on national market in Finland shows high success and client need: currently the loan application volume is over 4 B€, the company has over 400 000 customers, and over 40 service providers are using the platform. LVS Brokers delivers more business for banks and other companies, such as electricity companies, real estate agencies and insurance companies, and it saves time and money for corporate and consumer customers in brokering processes. The company targets emerging global market on online brokering services and has multiple scalability opportunities in service and market sectors. The commercialisation is well prepared, and the Phase 1 feasibility study will produce the detailed business plan to support the scale-up. The target is to reach 350 M€ growth during the 5-year period (2% market share). LVS Brokers has a talented and dedicated group of 7 with in-depth international business and industry expertise and technology understanding in the fields of software, AI, machine learning engineering and integrations. Ongoing recruitments and an active network of rele
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Senolytics repurposing in childhood refractory epilepsies' (EpiSen) targeting Horizon Europe.

assistant: **Abstract**

Epilepsy is a frequent neurological disorder characterized by recurrent seizures resulting from hyperexcitability and hypersynchrony of neuronal networks. Cortical malformations, including Focal Cortical Dysplasia (FCD), are rare sporadic diseases that cause early-life drug-resistant seizures for which surgery is the only therapeutic option to control seizures. Surgical inaccessibility and failures are significant clinical drawbacks. This emphasizes a critical and urgent need for new precision-based therapies for this debilitating childhood disorder. In recent years, my team contributed to revealing that FCD are caused by brain somatic mutations in genes belonging to the mTOR pathway, a signaling cascade regulating key physiological cell functions such as growth, proliferation, and metabolism. During the course of my ERC-funded project, we discovered specific biomarkers in both human and mouse preclinical FCD brain tissues. In EpiSen, we propose an innovative pharmacological strategy based on the selective elimination of mutated cells by repurposing available molecules, that are currently used in clinical trials in other diseases, for FCD-related epilepsy. We hypothesize that abnormal cells, once acutely cleared, will offer a prolonged benefit on seizures. Direct users include applied research groups, pharma companies, the medical community for clinical trials, and patient associations.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Thixoforming of Advanced Light Metals for Automotive Components' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

BE95-1244 Thixoforming of Advanced Light Metals for Automotive components The pressure on car manufacturers to reduce weight is continuously increasing; this can effectively be achieved by replacing components traditionally made from iron and steel with new, possibly redesigned components made of light metals. Due to the higher material cost it is necessary to use more cost efficient manufacturing processes, e.g. near-net-shape thixoforming. Three advanced material groups will be investigated: aluminium and magnesium alloys in addition to aluminium metal matrix composites (Al-MMCs). The objectives of this proposal are therefore to: - develop and produce advanced thixoformable alloys of Al, Al-MMCs and Mg, - study and model the thixoforming process, - manufacture automotive components by near-net-shape thixoforming of all 3 alloy groups, - determine the properties and performance of these real components, - assess the cost effectiveness of the process, and - compare the overall properties and cost effectiveness of components made from the three light metal groups. The following achievements are expected: - near-net-shape thixoforming of minimum 3 light weight components with satisfactory properties and performance, - weight reductions of 30-40% over components made from iron and steel - cost savings of min. 15-20% over light weight components made traditionally. In addition to the research organisations/universities the Consortium consists of 3 material producers, 2 manufacturers and 2 very large industrial conglomerates as end-users. This combination of industrial partners will ensure a very fast exploitation of the results of this project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Developing the predictive ecology of plant-animal interactions across space and time', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

In the face of the alarming pace of recent environmental change we lack the tools to accurately predict how biodiversity and ecosystem services will respond. One key gap in knowledge that limits our predictive ability is uncertainty concerning how the biotic interactions will change. Developing a predictive science of species interactions requires integrating evolutionary, biogeographic and ecological mechanisms acting at different spatial and temporal scales. We will use a hierarchical cross-scale approach, combining phylogeography, network ecology, statistical modelling and experiments, to disentangle the mechanisms governing species richness and mutualistic interactions in tropical hummingbirds and their food plants.  Hummingbirds and their food plants are an excellent model system because they are highly diverse, highly specialized, and logistically feasible to study. Our objectives are to (1) evaluate the influence of factors, such as trait-matching, environmental conditions and relatedness, on network structure; (2) quantify how and why interaction beta-diversity (i.e., reflecting the change in both species composition, and in interacting partners) changes across elevation gradients in each of three biogeographic regions with distinct evolutionary histories (mountain regions in Costa Rica, Ecuador, Brazil); (3) evaluate the importance of multiple factors, such as trait-matching, environmental conditions, relatedness and abundance, on species interactions and network structure; and (4) develop a predictive model of species interactions and evaluate its performance using cross-validation and experimentation. Together, these tasks will provide new insight into one of the central enigmas in ecology, namely, why species diversity and its interaction architecture change
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Electronic commerce in the cannery industry' under Fifth Framework.

assistant: **Concept**

The main objective of e-canned is to demonstrate the advantages of e-commerce for the cannery sector. Within the frame of this wide defined aim the main objectives are to reduce cost and time that canneries have for frozen storage of primary resources and to provide them a broader offer.It is also an objective of e-canned to increase the customers and of sales of the canneries by creating a virtual mall and selling their products via Internet. With a broad and targeted dissemination of the proceedings and results of e-canned the aim is to gain more users. Another objective is a clear documentation of a concrete business case of a cannery.The global objective of e-canned is to raise awareness of the possibilities that new technology has in store for the European industry.