RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Development of a Next generation European Inland Waterway Ship and logistics system', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The proposed project “Development of a Next generation European Inland Waterway Ship and Logistics System” aims at1.developing and validating a novel container ship (hull) which will include the following TECHNICAL INNOVATIONS:a)re-design of a standard inland ship hull = increase of transport efficiency (+ 100%)b)adaptable draught = crossing below even low bridges and react to altering water-levels = increase of days of navigability (+88% - 320 days instead of 170 days)c)an adjustable diesel-/gas-/LNG-electric energy- and propulsion system = increase of resource efficiency (up to 30%), decrease of harmful exhaust emissions2.tailoring a special-designed and integrated logistics system which will include the complying LOGISTICAL INNOVATIONS:a) an adapted logistics and supply system for the respective demands of market in the catchment areab) enlargement of the European inland waterway system for container transport = adapting the novel container ship for a use on UN-classes III and IV and making secondary waterways in Europe accessiblec) new river ports infrastructure conceptsd) re-evaluation of multimodal activitiesConcluding, the novel container ship will be able to meet operator’s targeted costs, optimize time-management (reliability), answer to inland shipping-specific bottlenecks (e.g. low bridges, shallow waters), improve carbon footprints and thus successfully compete with road and railway transport.A significant modal shift is aspired, especially to the Danube and its hinterland.One of the main results will be a finance and business plan to bring the novel ship AND the required logistical concepts to the market, designed to reach EU 2011 White Paper and to strengthen the Danube region.The consortium herewith applies for European funding as both technical AND logis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Defining the Role of Antioxidants on Cancer progression and metastasis'.

assistant: **Innovation**

Antioxidants, by neutralizing ROS and ROS-induced DNA damages, are thought to protect against cancer. Recently this common view was challenged by the observation that antioxidants may accelerate tumor progression in mouse models of lung cancer, by turning down the DNA-damage-gH2AX-p53 signaling pathway. This study raised new questions: Are antioxidants able to induce metastasis from benign tumors, by silencing p53 expression? Are cytosolic ROS equivalent to mitochondrial ROS for lung cancer progression?In a first part, I will test the hypothesis that antioxidants favor the metastatic process in lung cancer in state-of the art mouse models. I will administer NAC or vitamin E in the drinking water or the diet of the mice (Kras2LSL) after tumor initiation, and define their impact on metastasis and survival. Preliminary data showed that antioxidants are able to induce metastasis in this non-metastatic model. RNA from tumors and metastases of antioxidant-treated and control mice will be used for RNAseq to identify molecular events that accompany the antioxidant effect. These experiments should allow me to answer my hypothesis and provide new leads on the metastatic process of lung cancer. Lung cancer is indeed a metastatic disease that is still challenging to treat and in great need of new treatments.In a second part, I will investigate the impact of mitochondria-targeted antioxidant (mitoQ, a quinone targeting the inner membrane of the mitochondria) in order to specifically assess the role of mitochondrial ROS on tumor progression. I will administer mitoQ in the drinking water of mice after tumor initiation, and assess its impact on tumor progression. These experiments will allow me to determine whether mitochondrial ROS are pro-tumorigenic, as we hypothesize.Altogether thi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Synthesis of 2-D semiconductors with honeycomb nanogeometry, and study of their Dirac-type band structure and opto-electronic properties' (FIRSTSTEP) under Horizon 2020.

assistant: **Objectives**

Graphene redirected the pathways of solid-state physics with a revival of 2-D materials showing Diracphysics due to their honeycomb geometry. The charge carriers are fundamentally different from thosein conventional electronic systems: the energy vs. wave vector relationship is linear instead ofquadratic, resulting in Dirac bands with massless carriers. A genuinely new class of materials willemerge provided that classic semiconductor compounds can be molded in the nanoscale honeycombgeometry: The Dirac-type band structure is then combined with the beneficial properties ofsemiconductors, e.g. a band gap, optical and electrical switching, and strong spin-orbit coupling. ThePI recently prepared atomically coherent 2-D PbSe and CdSe semiconductors by nanocrystal assemblyand epitaxial attachment. Moreover, he showed theoretically that these systems combine asemiconductor gap with Dirac-type valence and conduction bands, while the strong spin-orbitcoupling results in the quantum spin Hall effect. The ERC advanced grant will allow him to develop arobust bottom-up synthesis platform for 2-D metal-chalcogenide semiconductor compounds withhoneycomb nanoscale geometry. The PI will study their band structure and opto-electronic propertiesusing several types of scanning tunnelling micro-spectroscopy and optical spectroscopy. The Fermilevelwill be controlled with an electrolyte-gated transistor in order to measure the carrier transportproperties. The results will be compared directly with those obtained on the same 2-D semiconductorswithout honeycomb geometry, hence showing the conventional band structure. This shouldunambiguously reveal the Dirac features of honeycomb semiconductors: valence band and conductionband Dirac cones, non-trivial band openings at the K-points that may host
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Quantum Transport in Nanoconstrictions made of no magnetic metals'.

assistant: **Concept**

Ability to exploit spin transport in semiconductor promises new logic devices with enhanced functionality, higher speeds and reduce power consumption. In addition, these new devices could be fabricated with many of the tools already used in the electronic industry. Therefore, one of the current objectives in the research in Spintronics is to develop new materials of easy compatibility with semiconductor materials and processing. Development of new materials suitable for spin-polarized transport supposes to devote many efforts and resources to the quest of 100 spinpolarized materials.The important room temperature ferromagnetic metals (Co, Fe and Ni) and their alloys have a spin-polarization of the carriers near the Fermi level of aprox. 50 %. Another research area, which provides serious challenge, is that of spin injection. Spin injection is the process by which a highly spin polarization current is transmitted from the ferromagnetic metal into another material such as another metal, a semiconductor, while retaining its spin-polarization character. The most difficult, and no doubt the most important, case of spin injection is that from a ferromagnetic into a semiconductor.However, despite considerable research efforts over the past decade, initial progress has been remarkably slow. Recent findings have been carried out by the Thin film Magnetism Group of Prof. Bland at Cavendish Laboratory concerning quantum transport in Cu nanowires. The nanowires were created by bringing macroscopic Cu wires into and out of contact, mechanically controlled break junction technique.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Automated and robotics-based techniques. New solutions for road construction and maintenance' (ART).

assistant: **Concept**

The ART Project aims at exploring the potential for introducing Automated and Robotics-based Techniques for road construction and maintenance (RICM) and pave the way for wider adoption of these technologies to the benefit of:a) road users,b) road management authorities,c) European manufacturers andd) road construction industry.ART techniques and technology have the potential to reduce the time required for RICM operations by 30-50% as well as the physical space required for such operations. The effects of such reduction in time and space requirements for RICM operations are:a) reduced operational costs,b) reduced environmental impact,c) reduced accidents,d) reduced delays to users,e) better quality and scheduling of RICM operations.The application of ART will result in lower cost and increased flexibility for RICM operation. This will give the opportunity to road administrators to allocate the limited funds available in a more efficient manner, ensuring a better maintained and safer existing road network and increased efficiency in the construction of new road related infrastructure. %
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'An experimental approach to the systematics of the diatom Pinnularia' (DIATPIN).

assistant: **Concept**

Among plants, diatoms are the second only to the flowering plants in terms of their biodiversity (c. 200,000 species) and their contribution to global photosynthetic productivity (c. 20% of the total annually). They are also the most important organisms fo r studying changes in water quality and aquatic conditions over time-scales of months to millions of years. Diatom taxonomy, however, is relatively primitive. During the last 30 years, species concepts have changed, from narrow to broad definitions and the n back to narrow ones, with accompanying confusing changes in nomenclature. The reasons for these changes have not been tested and it is not clear that the newest classification is the best. As consequence several incompatible classifications are in use, compromising ecological and other applied studies. Therefore, the main objectives of this project are to test the diatom species concept using the genus Pinnularia as a study model and to establish a secure taxonomy for Pinnularia. The genus inhabits mostly freshwater and reaches its maximum diversity in low electrolyte waters that are highly sensitive to environmental disturbance, thus it is a worthwhile subject of research. The objectives will be achieved by using recently developed mating protocols to investigate reproductive isolation; by complementing this with molecular genetic studies using appropriate markers (rbcL and ITS rDNA sequence analysis); and by testing agreement between morphology, molecular data and mating experiments. Therefore, the project and its objectives are relevant to the Specific Programme: III.1.1 and III.2.1. Working at the Royal Botanic Garden Edinburgh will provide advanced training in experimental culture techniques, the reproductive biology of diatoms and molecular methods i n a clo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Gradual and abrupt environmental change: connecting physiology, evolution and community composition'.

assistant: **Objectives**

A major goal in ecology is to predict how environmental changes, including drivers of global change, affect communities and ecosystem functioning, with society demanding answers to these pressing questions. A key limitation of virtually all experimental approaches addressing such questions is that treatments are delivered abruptly, while many changes occurring in nature are gradual. Here I propose to comprehensively study consequences of environmental change when delivered abruptly vs. gradually. In order to understand and model effects of gradual vs. abrupt changes, we need to simultaneously consider physiological effects (e.g. acclimation), evolutionary changes (e.g. adaptation) and changes in community composition and functioning. Even though changes at these levels likely interact, there is no study in which physiology, evolutionary changes and community shifts have been studied in response to a changing environmental factor. This research program thus enters unchartered territory of empirical environmental research in proposing work at this nexus of physiology, environmental change and community composition/ function. I focus on soil fungi, key players in terrestrial ecosystems, testing a range of gradually vs. abruptly changing environmental factors, in a range of soils, in the field and in microcosms. We connect differential responses to species traits, apply modeling and employ data syntheses across all biomes and organisms to achieve high external validity. We carry out a set of core experiments that will afford unprecedented insight into the nature of change in a community context in response to warming, focusing on soil fungi. In these we follow evolutionary change (phenotype and genotype), test physiological shifts by re-isolation of fungi and monitor commun
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'How do biotic and environmental variation affect soil microbial community composition and functioning across spatial scales?' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Soil microbial communities hold sway over numerous processes upon which we depend, driving the cycling of elements which sustain life, but also compromising food security and human health. Understanding the mechanisms driving existing soil microbial community diversity and function across disparate climates and ecological communities is key in order to determine future ecosystem responses to global change. Although studies aiming to characterise soil microbes are increasing in their scope, they will only capture the multifaceted interaction between diverse microbial communities if they measure the effects of above ground plant communities and the abiotic environment, when measured at appropriate scales across landscapes. The proposed MICOCO project will address these shortfalls to achieve the following objectives: [1] Determine the relative contribution of above ground plant community and soil abiotic conditions to SMC diversity and composition; [2] Determine how climate influences microbial community turnover at varying spatial scales; [3] Reveal the relative effects of microclimate, microbe-microbe associations, and microbe-plant associations on microbial function. These objectives will be achieved using novel datasets built on the latest techniques in the sampling of environmental DNA (eDNA). These were collected at local scales (1-100m) in an innovative climate controlled mesocosm, and at landscape scales (100m->100km) as part of pioneering national surveys of soils. Cutting edge modelling techniques will be used to generate microclimate measures, and the latest Joint Species Distribution Models will determine association patterns within soil microbial communities, coupled with functional trait databases to identify plant pathogens and appropriately infer interactio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'From Wild to Domesticated: How do root traits and microbial communities affect soil carbon stabilization in cropping systems?' (ROOTEX-C).

assistant: **Concept**

Domestication resulted in a loss of crop diversity, and greater susceptibility to biotic and abiotic stressors. But did this transition to domesticated varieties also influence soil carbon (C) stabilization pathways? To address this question ROOTEX-C will bring together a multidisciplinary team with expertise in plant physiology, microbiology, biogeochemistry, and soil science. The aim is to investigate how belowground plant traits, such as root architecture and exudation patterns, interact with microbial communities and influence soil C stabilization across different crop domestication statuses. By employing cutting-edge methodologies, including metabolomics, metagenomics, stable isotope probing, and novel methods for estimating microbial carbon use efficiency (CUE), ROOTEX-C aims to significantly advance our mechanistic understanding of plant-soil C processes and gain insights into the effects of crop domestication on plant belowground traits. Project findings could ultimately inform crop breeding programs and agronomic practices that seek to enhance soil C contributing to both global food security and climate change mitigation. Beyond its scientific contributions, this project is pivotal for the fellow's professional development. By acquiring advanced interdisciplinary skills in microbial ecology, biogeochemistry, and plant physiology, she will gain the technical expertise required to tackle complex environmental and agricultural challenges. The collaboration with leading institutions and renowned experts will not only enhance her technical skill set but also strengthen her professional network, fostering future interdisciplinary research collaborations. The experience will significantly enhance her career prospects, positioning her for leadership roles in both acade
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Functional Microscopy of Individual Neurons in the Living Human Retina' in the context of a Horizon Europe call.

assistant: **Objectives**

Subcellular, functional imaging of neurons in living humans could revolutionize biomedical research and prove valuable in the clinic. With optical techniques, subcellular resolution is achievable and although the eye provides optical access to the retinal neurons, the size of the eyes pupil currently prevents subcellular resolution in all optical imaging techniques of the living retina. In this project, I will develop a novel tomographic microscopy technique and use it to demonstrate at least a 4-times better resolution for retinal tomography compared to the state-of-the-art. For the first time, a resolution below 1 m will be achieved for imaging of the living human retina. For this, I will use innovative structured illumination and reconstruction techniques that project coherent light through the sclera (transscleral) or the skull (transcranial), allowing for unprecedented resolution in 3-D retinal tomography. My method will use interferometric detection with noiseless amplification and exploit recent computational methods to reconstruct and correct the data. In addition to morphology, my technique will also assess the functional state and activity of neurons after optical stimulation of the photoreceptors. For this, I will harness changes in phase and speckles of the image data caused by physiological processes. This imaging will be non-invasive and without contrast agents. With this technology, I want to enable researchers and clinicians to study the detailed structure and function of individual neurons and their interactions in the living human eye with microscopic 3-D tomography. This revolutionary approach may provide new insights into human physiology and aid in the diagnosis and treatment of ophthalmic and neurological conditions.With a strong background in high