RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Moving Forward: Implementing the EU Space Strategy for Security & Defence (2028 – 2034)'.

assistant: **Concept**

The EUSTAR project critically examines the implementation of the EU Space Strategy for Security and Defence, identifying significant gaps in current policy frameworks, particularly regarding regional contributions and stakeholder integration across Europe. Despite the EU’s recognition of space as a vital domain intersecting multiple policy areas, the strategy has not been thoroughly analyzed from an interdisciplinary social sciences perspective. EUSTAR addresses this gap by focusing on three key areas: the need for a comprehensive assessment  of the EU Space Strategy for Security and Defence and its objectives in anticipation of the Multiannual Financial Framework (2028-2034); the overlooked role of Regions as pivotal subnational actors in European space policy; and the limited scholarly attention paid to European space policy. Utilizing an interdisciplinary methodology that incorporates qualitative and quantitative research, scenario planning, foresight methodologies, and extensive stakeholder consultations, EUSTAR develops nuanced policy recommendations aimed at optimizing strategic alignment, enhancing regional engagement, and fostering cross-sectoral innovation. The project also emphasises inclusivity by integrating gender and diversity considerations into its analysis, thereby addressing systemic inequalities within the space sector. The expected outcomes include the advancement of theoretical frameworks for understanding European space policy, practical recommendations for resource allocation within the Multiannual Financial Framework (2028-2034), and the creation of an open-access toolkit for stakeholders. By bridging academic and policy-oriented approaches, EUSTAR will contribute to a more integrated and effective implementation of the EU Space Strategy for Secu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Prediction of ash and deposit formation for biomass co-combustion', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Objectives of the Project In comparison with other renewable energy sources the thermal utilisation of biomass or waste Is an economical, sustainable and technical feasible option to contribute towards reducing the net C02 emissions, one of the principal goals of the European Union. Co- combustion of biomass or wastes together with coal in existing large-scale pulverised fuel firing systems offers several advantages, e.g. the possibility to utilise a large quantity of biomass at lower investment costs compared to systems exclusively fired with biomass. However, due to its wide range and properties, biomass as feedstock is a complicated fuel and there is increasing concern about ash deposition-related effects and excessive rates of corrosion in advanced plants. The objective of the project therefore Is to provide predictive tools For the specific operational problems slagging, fouling and corrosion in pulverised fuel co-combustion of biomass In advanced high temperature power plants. Technical approach The work program consists of experimental and analytical work on corrosion, slagging and fouling as well as related chemistry. In parallel experimental work and analytical methods will provide methods for pilot scale test procedures Applied chemical tools for analysis and the description of mechanisms will validate the experimental and analytical results. Corrosion tests will concentrate on the physical and chemical processes involved at higher metal temperatures. Eleven mainly Industrial or industrial orientated partners will investigate in close cooperation: . - the slagging and fouling potential of different fuel mixtures using various techniques in lab scale, pilot scale, and full scale facilities - the corrosion mechanisms in biomass-combustion by means of corrosion t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Enabling the large-scale deployment of Facial Recognition in banking security' (FACCESS) under Horizon 2020.

assistant: **Objectives**

In the FACCESS project we aim at performing a pilot study for the large-scale implementation of our face recognition technology in banking security. There is strong demand in the banking industry for secure biometric applications. In fact, in May 2014 the European Central Bank (ECB) published a list of recommendations for increased bank transaction security and for the first time, biometrics was included as one of most valid and securest authentication parameters. Security has been always a major concern of the banking industry, fundamentally because banks are attractive to criminals as a direct access to currency, bank notes, and user‘s personal information which can be used for identity theft (phishing and card skimming). The concerns about bank security have always been there, but it has been after the breakthrough of online and mobile banking when bank fraud has become major issue to address with urgency. Currently, whether it’s online, on a smartphone, on an ATM or on a POS (point-of-sale), the great majority of banking transactions are done by using a 4-6 digits PIN code as the way for authentication. This form of authentication is of an extremely low security level in all cases, but especially more in online banking where cybercriminals and hackers can easily obtain this PIN code in a matter of seconds. As a result, the total value of fraudulent transactions is rapidly increasing year by year, being now estimated at €1.33 billion solely in Europe.  In this scenario, biometrics holds great promise to become the gold standard authentication method for bank transactions in the near future. However, despite the clear opportunity there are still some barriers preventing the banking biometrics breakthrough, at least on a large scale. Our Facial recognition technology g
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how '4th european conference on grain legumes: towards the sustainable production of healthy food, feed and novel products' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

The proposed project is to organise an international and multidisciplinary scientific conference on grain legumes in the geographic centre of Europe, Krakow in Poland, under the title: 'Towards the sustainable production of healthy food, feed and novel products'. The combination of plenary and workshop sessions of the Conference will allow attendants to acquire both an up- dated overall picture in the major areas as well as an advanced view in selected scientific and technical issues relating to grain legumes. The Organising Committees will ensure the high standard in the scientific content and the logistics. The permanent Executive Secretariat, which is in charge of the coordination of the on-going thematic network LINK (FAIR CT98- 3923), will ensure the communication and the following-up of the outputs. It will facilitate the future collaborations among the scientific community and the private partners for an enhanced production and utilisation of grain legumes to contribute to a sustainable agriculture and to safe and healthy protein-rich products for feed and food industry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Protein phosphatase 1-disrupting peptides: Scope and mechanism of action in the treatment of heart insufficiency'.

assistant: **Concept**

Protein phosphatase-1 (PP1) is a ubiquitously expressed enzyme known to dephosphorylate a large number of the phosphorylated serines and threonines. The catalytic subunit PP1c is bound to regulatory proteins in holoenzymes. These play specific and fundamental roles in physiological processes and pathologies. One key role lies in the regulation of important cardiac signaling pathways and calcium homoeostasis. Accordingly, deregulation of PP1 has been implicated in cardiac dysfunctions. Powerful tools to study PP1 biology are our own developed PP1-disrupting peptides (PDPs) that selectively release PP1c (bound to PDP: PDP–PP1c) activity in cells. Recently, we showed that PDP treatment counteracts kinase hyperactivity and seals the arrhythmogenic sarcoplasmic reticulum (SR)-calcium-leak in human heart failure tissue. Mechanistic data indicated that PDP–PP1c-mediated dephosphorylation of the ryanodine receptor type 2 (RyR2) is involved in this effect. Nevertheless, given the large amount of potential PP1 substrates, so far the scope of PDP action is unknown, and therefore the mechanisms underlying this beneficial and potentially therapeutic effect of the PDPs in heart failure are unclear and currently hard to investigate.  PDPcardio will address these challenges by providing new chemical biology methodologies combined with proteomics approaches using PDPs to guide PP1c to its substrates and to identify PDP-mediated interactions of PP1. These strategies will enable identifying the scope of PDP action in general, and in particular they will be applied here in cardiomyocytes to study the effects of PDP–PP1c. The results will provide the basis to fine-tune targeting PP1 for the treatment of heart insufficiency. Furthermore, the principles and methods developed here will be appl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Advanced manufacturing process to obtain a partially Bio-Resorbable Adhesive/Non-Adhesive Triple Layer Mesh for intra-peritoneal Hernia Containment' to be submitted under Horizon 2020.

assistant: **Abstract**

3L-HeCoMe aims to provide efficient and effective industrial solutions to innovate the production processes and products for hernia containment. Ventral hernia repairs in Europe are 400.000/year, but post-operative complications still occur, namely recurrence due to prosthetic displacement and adhesions between viscera and prosthetic surfaces. Considering estimated costs for each ventral hernia repair in Europe, costs due only to recurrence amount to 36.732.000 €/year.The main aim of 3L-HeCoMe Feasibility Study(FS) is the development of an innovative process supported by enabling technologies derived from other applications and by the use of advanced materials to produce a unique medical device for the Intraperitoneal Treatment of Abdominal Wall Hernias (IPTAWH). The produced IPTAWH medical device (IPTAWH-MD) aims at preventing post-surgery problems and avoiding, or decreasing, use of mechanical surgery instruments for the mesh fixation. The IPTAWH-MD will reduce the surgical duration and costs, thanks to the following characteristics: ‐chemical adhesive properties to parietal tissues‐anti-adhesion properties to viscera ‐adequate mechanical properties,‐partial bioresorption.FS objectives: ‐investigate technical development, process customization and applicability ‐qualify 3L-HeCoMe process production output and constituting materials‐assess market potential and penetration routesFinal users are surgeons oriented towards simplified, faster and mininvasive procedure, in the global market, which amounts to about USD 500 million and has an estimated CAGR of 7.5%, bringing to 700 million in 2019. The resulting MD will substitute actual products, giving a solid position to the SME in global markets and increasing the income, with potential sales of 259.000 – 452.000 €/year fr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Evaluation and utilization of pineapple genetic resources from the Amazon to breed resistant varieties' to be submitted under Fourth Framework.

assistant: **Abstract**

The long-term objective is recovering or breeding pineapple varieties to improve production systems and provide the South American markets with larger quantities of high quality fruits, so contributing to the sustainable development of this region and the tropical small farming systems. The present project aims at obtaining knowledge and tools for the development of varieties resistant to the main diseases in the region, by :* characterizing and evaluating available genetic resources,* studying the genetic structure of the genus Ananas,* developing resistance screening techniques,* studying the heredity of agronomic traits,* test the potential of partial inbreds in breeding.Expected OutcomeThe project will favour new uses of neglected or traditional varieties, so widening the genetic base of pineapple cultivation. Agro-morphological and genomic studies will provide key information to assess the genetic diversity of pineapple and understand its structure. The database will allow better management and exploitation of the collections. The development of new breeding schemes associated with gene mapping should greatly improve breeding efficiency, allowing to transfer resistances and thence promote integrated and more environmentally friendly pests and diseases control.The project will specifically :* Characterize the germplasm collected in a previous series of projects (botanical and agromorphological description, nuclear and cytoplasmic DNA characterization); study the structure and genetic diversity of the genus Ananas; evaluate the potential for breeding or direct use in small farmers systems.* Create a standard database to promote information and germplasm exchange between the partners, and, later, between all the existing pineapple germplasm collections.* Develop techn
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'LCTB-21: A DYRK1A protein kinase inhibitor for treatment of cognitive decline in Down Syndrome.' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

All people with Down Syndrome (DS) suffer from a certain level of impaired learning and memory (cognitive disorders) from childhood onwards, greatly impacting their autonomy and societal integration. This is becoming an increasingly urgent issue as people with DS are more often outliving their care takers, yet an adequate treatment has not yet been developed.Studies have revealed that the cognitive decline in people with DS is associated with overexpression of the DYRK1A protein kinase in the brain. Perha Pharmaceuticals has developed a novel therapeutic compound, Leucettinib-21 (LCTB-21), which acts as a DYRK1A inhibitor that can reduce cognitive decline in children with DS. Ultimately, this will increase the autonomy of people with DS resulting in better societal integration. Perha Pharmaceuticals aims to outlicense LCTB-21 to a large pharmaceutical partner (e.g. Otsuka Pharmaceuticals, Intra-Cellular Therapies) following a successful phase 2a clinical trial.


**Keywords:** Down Syndrome,Alzheimer's Disease,DYRK1A inhibitor,Kinase inhibitor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'SCAlable LAttice Boltzmann Leaps to Exascale', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

In SCALABLE, eminent industrials and academic partners will team up to achieve the scaling to unprecedented performance, scalability, and energy efficiency of an industrial LBM-based computational fluid dynamics (CFD) software.Lattice Boltzmann methods (LBM) have already evolved to become trustworthy alternatives to conventional CFD. In several engineering applications they are shown to be roughly an order of magnitude faster than Navier-Stokes approaches in a fair comparison and in comparable scenarios. In the context of EuroHPC, LBM is especially well suited to exploit advanced supercomputer architectures through vectorization, accelerators, and massive parallelization.In the public domain research code waLBerla, superb performance and unlimited scalability has been demonstrated, reaching more than a trillion (10^12) lattice cells already on Petascale systems. waLBerla performance excels because of its uncompromising unique, architecture-specific automatic generation of optimized compute kernels, together with carefully designed parallel data structures. waLBerla, however, is not compliant with industrial applications due to lack of a geometry engine and user friendliness for non-HPC experts. On the other hand, the industrial CFD software LaBS already has such industrial capabilities at a proven high level of maturity, but it still has performance worthy of improvement. Therefore, SCALABLE will transfer the leading edge performance technology from waLBerla to LaBS, thus breaking the silos between the scientific computing world and physical flow modelling world to deliver improved efficiency and scalability for LaBS to be prepared for the upcoming European Exascale systems.  The project outcomes will directly benefit to the European industry as confirmed by the active
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Fullerene-based opportunities for robust engineering: making optimised surfaces for tribology' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

The overall objective of the integrated project is to provide industry with radically new composite coating systems, based on the incorporation of inorganic fullerene-like nanoparticles. The application of the composite coatings will be for surfaces and lu bricants, in order to significantly reduce and control friction and wear in tribological contacts. The ultimate aim is to reduce friction as well as to extend operational life, reduce maintenance requirements and reduce the environmental impact of a wide r ange of mechanical elements for the aerospace, automotive, power generation (energy) and manufacturing industrial sectors. The new materials that will be developed can be grouped into three categories: Nanocomposite hard coatings, consisting of a hard matr ix containing self-lubricant fullerene-like (FL) nanoparticles Polymeric coatings and paints incorporating the Fullerene-like nanoparticles Lubricants and greases containing fullerene-like nanoparticles for complex systems where only some parts can be lubr icated or coated with the new nanocomposites These new materials will allow independent control of tribological properties usually known as antagonists (very high load bearing capacity with a very low friction coefficient). This breakthrough in coatings an d materials design will mean a radical innovation in lubrication and wear protection concepts, rather than an incremental advance in either reducing wear or improving friction behaviour. Success will require the development of innovative coating processes and incorporation techniques for the production of these unique nano-composites. Although initial work will focus on the incorporation of existing inorganic fullerene nanoparticles with onion-like or nanotube structures, significant research effort will be co