RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The fate of TERRestriAl forest CARBon from photosynthesis to structural biomass under climate change' (TERRACARB) under Horizon 2020.

assistant: **Objectives**

Forests play a major role in the global carbon cycle. They uptake carbon through photosynthesis, return much of it through respiration, and accumulate some fraction as structural biomass (Bst). The forest carbon sink offsets nearly 30% of anthropogenic carbon-dioxide emissions, with Bst being the primary contributor to this sink due to its slow rate of turnover (years to centuries). However, climate change is increasing the frequency and intensity of drought events and negatively impacting both photosynthesis and Bst. As these two processes are interconnected but independently modulated by environmental variables, it is imperative that we track the fate of forest carbon through its lifecycle from uptake to allocation. In TERRACARB, we will investigate the interactions between climate, photosynthetic carbon uptake, and carbon allocation to Bst during drought across spatial and temporal scales (tree to global; hourly to decadal). To do so we will use an innovative interdisciplinary approach that combines remote sensing, eddy covariance, tree-rings, and point dendrometer derived estimates of productivity. First, we will investigate the decrease in photosynthetic carbon uptake during atmospheric and hydrologic drought. Next, we will examine the mechanisms by which drought events leave behind legacy effects of below normal carbon accumulation. Finally, we will use a network of point dendrometers to evaluate the relationships between photosynthetic carbon uptake, tree radial growth, hydration, and climate variables at sub-seasonal timescales (hourly to daily) at five eddy covariance sites in Europe. The findings from TERRACARB will help us better predict how forests will continue to accumulate carbon in the face of climate change.


**Keywords:** Remote Sensing, Tree Rings, E
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Lipoproteins and angiogenesis: A new look at an old problem' in the context of a Seventh Framework call.

assistant: **Objectives**

Cardiovascular diseases (CVDs) are the leading cause of death throughout the world. Elevated Low Density Lipoprotein (LDL) is a well-known cardiovascular risk factor and endothelial (ECs)-lipoprotein (LIPs) interactions underlie the initiation and progression of atherogenesis, thrombosis and other CVDs.The endothelium is a monolayer of cells that segregates the vascular contents from adjacent tissues. In spite of being continually exposed to LIPs, ECs were long thought of as inert barriers, through which lipids are exchanged between plasma and surrounding tissues. In contrast to this view, recent work from my laboratory has uncovered a deleterious role of ApoB-LIPs as direct inhibitors of angiogenesis in the developing embryo. These findings present only the tip of the iceberg, and the underlying cellular and molecular mechanisms are largely unknown. In this proposal, we will tackle this question by undertaking three independent but complementary approaches, aimed at characterizing LIP-EC interactions at a different level: cellular, molecular or pathological. We will explore these facets in zebrafish and mammals, utilizing live imaging, sophisticated lipidomic and biochemical analyses, as well as tumor xenografts and genetic mutants. An important and unique aspect of our approach is the focus on in vivo dynamics, in contrast to the extensive body of literature on LIP effects on cultured ECs. When completed this proposal will have shed light on a little explored, but critical aspect in the etiology of CVDs. Furthermore it will provide answers to important unresolved questions: What are the signaling pathways activated in ECs upon LIP binding? How are LIPs transported within ECs? Does ApoB possess additional functions beyond that of cholesterol carrier? Can high LIPs leve
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'TALOS-Artificial Intelligence for Humanities and Social Sciences' (TALOS-AI4SSH), addressing dissemination and exploitation.

assistant: **Impact**

The proposed project aims to establish a Centre on Artificial Intelligence for Humanities and Social Sciences, under the leadership of outstanding academic Christophe Roche, at the University of Crete, in Widening country, Greece. Christophe Roche, currently a Professor of Artificial Intelligence in France, has proven research and innovation excellence, keen management skills, and extensive academic, standards and industry connections; most importantly, he has already established collaborations with the University of Crete and has committed to work with its staff to help build a leading-edge Centre of excellence, integrated in the European Research Area. The objectives set by this project align with the EU SSH and digital agenda to expand the research and innovation potential, generate new knowledge, strengthen innovation and knowledge transfer activities, create industry driven projects and build capacity through combined academic-industry training, in close collaboration with local and global industry partners, support SSH informed evidence-based AI policymaking, develop key combined digital SSH competencies and produce interdisciplinary solutions to both societal and technological AI issues. In order to achieve its objectives, the newly created Centre will attract and maintain highly talented staff and PhD students under the direction of the proposed ERA Chair holder, while at the same time boosting the digital skills of existing staff and implementing structural changes necessary in the university to achieve a world-class and sustainable hub. Research excellence in this field will allow the University of Crete to participate in, and potentially lead, Research and Innovation across the commercial, cultural and social sectors, achieving high impact outcomes for scienc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Screening for cancer in the post-genomic era: diagnostic innovation and biomedicalisation in comparative perspective' (CANCERSCREEN) targeting Horizon 2020.

assistant: **Abstract**

Cancer screening and the diagnostics industry: a comparative analysis of the political economy of diagnostic innovationA decade after the Human Genome Project, major public and private investments continue to fuel expectations of a genomic revolution in biomedicine. The freight of expectations surrounding the new “age of diagnostics” is accompanied by much uncertainty about how public policy should steer diagnostic innovation, with much debate about inter alia the harms of creating diagnostic monopolies through gene patenting, and the risks of under- or over-regulation. However, due to the paucity of research on diagnostic innovation, policy deliberation is driven more by anecdote and expert opinion than empirical evidence. With a specific focus on screening/early detection of cancer, this project will map industry dynamics, technological trajectories and regulatory developments in Europe and the USA from 1996 to the present day. Combining quantitative and qualitative methods, the project’s innovative dimensions include a new conceptual model of socio-technical transition in the diagnostics sector, and the first integrative analysis linking scientometric data on the interactions between public and private actors in the diagnostic research domain with comparative transnational analysis of regulatory decision-making. Through a novel integration of conceptual insights from the literature on biomedicalisation and scholarship on socio-technical regime change, this project aims to advance both fields of research by applying a new multi-scale, multi-level model of socio-technical transition. The project will provide unprecedented insight into the factors shaping the development of a new generation of molecular diagnostic tests, and examine how these technologies are reconfigur
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Wearable Cardiorespiratory Monitor' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The research topic of WECARMON deals with biomedical signal processing, specifically, the analysis of electrocardiogram (ECG) signals for cardiorespiratory system assessment. WECARMON’s main objective is to develop novel system for early non-invasive detection of clinical destabilizations of patients with chronic respiratory diseases, e.g., chronic obstructive pulmonary disease (COPD) and asthma. Its innovative nature is based on two main tools: 1) a long-term (months) wearable ECG device which uses dry electrodes which causes no skin irritation and which are placed in a left leadless armband, and 2) signal processing techniques for estimating respiratory rate and volumes from ECG which are robust against artefacts generated by movements during daily life.Chronic respiratory patients are affected by destabilizations (or “exacerbations”) which makes them to seek medical help and often lead to their hospitalization. Exacerbations can start quickly (in minutes to hours) and they are one of the main causes of mortality among patients with COPD and asthma which are the two most common chronic respiratory diseases, affecting millions of children and adults. Among the wide range of applications of a wearable cardiorespiratory monitor related to intensive care units, respiratory disorders and health monitoring, the chosen application of WECARMON is the daily ECG and respiratory monitoring in COPD and asthma patients for early detection of exacerbations allowing a better prognosis of the patient and a reduction of financial costs to society.WECARMON can be divided in 2 phases: 1) Development of a long-term (months) wearable ECG and respiration monitor, and 2) Development of an automatic algorithm for early detection of COPD and asthma exacerbations, based on cardiorespiratory pa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Textuality and Diversity: A Literary History of Europe and its Global Connections, 1545-1659' (TextDiveGlobal).

assistant: **Innovation**

This five-year programme of investigation of 52 textual corpora includes Mesoamerican codices, Jesuit neo-Latin plays, popular songs, Kongolese documents in Portuguese, Cervantes’ works, examples of live speech from archives, and many others. It will produce an interdisciplinary literary history of Europe and its global connections for the period between the mid-sixteenth and mid-seventeenth centuries. The Reformation had fragmented Christendom into differing religious identities. Europeans were multiplying encounters with peoples and cultures in the Americas, Africa, and Asia. TextDiveGlobal challenges the legacy of nineteenth-century European literary-historical scholarship insofar as it durably organised the textual heritage connected with Europe from the perspective of distinct western European national literary canons and histories, and the comparisons and relations between them. Using analytical and linguistic-geographical criteria, it selects a wide and multilingual range of textual objects and forms both made and encountered by Europeans, in relation to spaces from Mexico to China, and events from the Church Council of Trent (1545) to the diplomatic Treaty of the Pyrenees (1659). The objective is to understand how textual and sociocultural diversity inform one another in different contexts and regions of this multifarious world. The methodology is a global-historical anthropology of texts grouped into corpora assembled on four interrelated principles: works, forms, spaces, events. Outputs include a two-volume summa (Oxford University Press), a database of information and images relating to the corpora, and a series of seminars across the USA and Europe. In each of five year-long phases of the research, a sub-team of experts and PDRFs will meet with the PI across
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Strong interactions for precision nuclear physics' to be submitted under Horizon 2020.

assistant: **Abstract**

Nuclear physics is a cornerstone in our scientific endeavour tounderstand the universe. Indeed, atomic nuclei bring us closer tostudy both the stellar explosions in the macrocosmos, where theelements are formed, and the fundamental symmetries of themicrocosmos. Having access to a a precise description of theinteractions between protons and neutrons would provide a key tonew knowledge across 20 orders of magnitude; from neutrinos toneutron stars. Despite a century of the finest efforts, asystematic description of strongly interacting matter at lowenergies is still lacking. Successful theoretical approaches,such as mean-field and shell models, rely on uncontrolledapproximations that severely limit their predictive power inregions where the model has not been adjusted.In this project I will develop a novel methodology to useexperimental information from heavy atomic nuclei in theconstruction of nuclear interactions from chiral effective fieldtheory. I expect this approach to enable me and my team to makeprecise ab initio predictions of various nuclear observables in awide mass-range from hydrogen to lead as well as infinite nuclearmatter. I will apply Bayesian regression and methods from machinelearning to quantify the statistical and systematic uncertaintiesof the theoretical predictions. The novelty and challenge in thisproject lies in synthesising (i) the design of nuclearinteractions, (ii) ab initio calculations of nuclei, and (iii)statistical inference in the confrontation between theory andexperimental data. This alignment of methods, harboured withinthe same project, will create a clear scientific advantage andallow me to tackle the following big research question: how canatomic nuclei be described in chiral effective field theories ofquantum chromo dynamics?


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system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Raise excellence in R&S&I in HEI for widening countries' to be submitted under Horizon Europe.

assistant: **Abstract**

The ability to conduct successful transnational R&I projects in the EU varies between countries due to recognised gaps, including lack of scientific infrastructure, ability to maintain and retain talents or to overcome regional or national structural barriers. Concerted and directed efforts are required to support lesser-performing countries, like Portugal and Poland, to bridge these gaps and strengthen R&I across Europe.All academic contributors to the Unite!WIDENING project is also a partner in the European University Alliance Unite! “University Network for Innovation, Technology and Engineering”, a transnational alliance born in 2019 and contributing to the European Universities Initiative.The goal of Unite!WIDENING is to strengthen Unite! as an alliance, enhancing the scientific, technological and innovation capacity of the consortium of HEIs, raising its excellence as a group and individually, extending and expanding its activities, and implementing ERA/Widening policies. With the support of relevant partners in the local innovation ecosystems, it aims to accelerate the necessary reforms and conduct the required competence buildup to raise excellence in R&I and improve the valorisation of science and research in Widening countries. The results of Unite!WIDENING include new policy recommendations for R&I in Widening countries,  identification of gaps and future actions; the development of a Handbook of HRS4R for Widening countries; gender, inclusion and equity plans in research careers;  a university open science and strategic innovation roadmap; guidelines to the creation of local Science and Innovation Skills Academy, training programmes contents and guides, development of the research transparency dashboard and policies & strategies leading to reform and renewal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Evidence-based Medicine COllaboratioN NEtwork for guideline development, teaChing and disseminaTion' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

EBM CONNECT aims to harness the combined research expertise of several centres in evidence-based medicine or EBM. We will focus on development of state-of-the-art methodology for systematic reviews and practice guidelines in maternal health. These will be employed for improving research skills throughout the European Union and the developing world and for promoting effective healthcare through research based practice and policy. Not only will the centres benefit from staff exchange to develop their own research skills, this project will advance the frontiers in research synthesis. It will create the ability to conduct multinational projects and establish an electronic platform for research communication and collaboration. By establishing a worldwide agenda and a critical mass through the exchange, it will generate momentum that will allow development to continue thereafter. This is vital with reference to improving maternal health, as this is an area where disparity exists not only worldwide but also between EU member states. The exchange scheme will be based around three main objectives. First, to increase research skills through the sharing of each participant’s expertise. Second, to develop new methods for searching, quality assessment and meta-analysis to improve the standard of reviews and guidelines produced. This will include appraisal and adaptation of these reviews and guidelines to ensure they can be utilised widely within and outside the EU, including translation into Chinese and Spanish. Third, to establish a cutting edge research seminar series for widespread dissemination of the work. There are a number of elements that are integral to the strength of our proposal. We have well-established and internationally recognised generic expertise in evidence synthe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Expression of malaria parasite invasion-associated proteins in the sporozoite: Novel vaccination strategy' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

In human sterile immunity against malaria has been obtained only after exposure to irradiated sporozoites inoculated by mosquitoes. The full repertoire of pre-erythrocytic antigens that underlie this sterile protection is not actually known. The three antigens (CS protein, thrombospondin-related anonymous protein, and Liver stage antigen 3) investigated to date as vaccine candidates may not be responsible for induction of optimal protective responses. This would account for the difficulties encountered in reproducing this sterile long-lasting immunity by experimental subunit vaccines based on these antigens. It would clearly be desirable to investigate other pre-erythrocytic antigens. Such efforts to expand targets of pre-erythrocytic stage immunity are justified because the infection is at its most vulnerable during the 5 to 14 days between sporozoite inoculation and the emergence of hepatic merozoites into the blood stream. During this period two distinct stages (sporozoite and liver stages), whose numbers rarely exceed 100 in the human body, can be efficiently targeted by humoral and cellular immune mechanisms. In the last few years it was discovered that Plasmodium sporozoites express protein members of the EBL and the RH family thought till then to be exclusive to the erythrocytic stages of the parasite. Moreover, sporozoite penetration and/or development can be inhibited by antibodies specific to some of these proteins. This confirms that members of the EBL and RH families may play a functional role during the pre-erythrocytic stages of the malaria infection.The global objective of this proposal is to establish whether a newly described set of host cell invasion-associated proteins can serve as novel targets of inducible protective immune responses against pre-ery