RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Multimodal, high-resolution modeling of the thalamus for neuroimaging studies: application to dyslexia' under Horizon 2020.

assistant: **Concept**

The thalamus is a brain structure that is responsible for important functions (e.g., sensory systems, sleep, the motor system, spoken language) which are distributed over its 12 nuclei . While recent advances in MRI technology have made it possible to image the thalamic nuclei in vivo, the lack of specific computational tools to analyze the images forces most research studies to either treat the thalamus as a single structure (limiting the spatial specificity of the analysis) or to rely on the excruciating process of manually labeling the data. Since very few sites currently possess the anatomical expertise and staffing resources to carry out studies based on manual delineations, the lack of tools to analyze MRI data of the thalamus is hampering progress in different branches of neuroscience.Here we present an interdisciplinary project to build tools to automatically analyze the thalamic nuclei in MRI data. The tools will be based on a statistical atlas of the thalamus built upon ultra-high resolution MRI and histological data from autopsy samples. We will use the tools in a study of the relation between thalamus and dyslexia, where they promise to increase our understanding of the pathology by testing which nuclei are affected and to what extent. In addition, the tools will be distributed as part of the software package FreeSurfer, allowing its over 10,000 worldwide users to carry out cognitive neuroscience experiments at the nucleus level, and to discover new imaging biomarkers of other diseases related to the thalamus, e.g. Alzheimer's, Parkinson's, MS and ALS.This project will allow the host to acquire knowledge in medical image analysis from the applicant and to establish collaborations with Harvard and Oxford (host of the proposed secondment). The project will als
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'NMR relaxation tools  for improving and protecting  quality of dairy products'.

assistant: **Concept**

NMR-IMPROV  proposes a radically new approach to  investigating  properties of dairy products by exploiting Nuclear Magnetic Resonance (NMR) relaxation, including Fast Field Cycling and Time-Domain NMR methods.  The core of the concept is to acknowledge that macroscopic properties of dairy products are largely determined by dynamics of individual molecular fractions (from macromolecules to water) present in the system. Revealing and understanding the dynamics and arrangement of molecular fractions consisting dairy products is essential for providing a foremost guideline for designing products of required rheological  properties and texture, avoiding effects such as aggregation or phase separation, and  assessing authenticity of the products.  The goal of NMR-IMPROV is to form an interdisciplinary and intersectoral network including physicists, chemists, mathematicians, food scientists and engineers and software and electronic engineers to develop NMR relaxation based means to gain knowledge on dynamical properties of dairy products on the molecular level. Relationships between NMR relaxation parameters and  macroscopic properties  of dairy products,  investigated  by conventional methods, will be established. The knowledge is meant to be exploited to address challenges of dairy technology associated with development and storage of products that are fermented, plant-based, personalized and manufactured from local raw goods. Moreover NMR-IMPROV aims at establishing NMR relaxation as a tool for evaluating quality and authenticity of dairy products. NMR-IMPROV builds a bridge between specialists from academia, with deep expertise in NMR relaxation, and food scientists and engineers for the ultimate goal of transferring NMR relaxation from academia to dairy industry. This is
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'INSECT-PARASITE interactions : MOLECULAR ASPECTS of INFECTION AND IMMUNITY in DIPTERA', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Transmission of the malaria parasite (genus Plasm odium) from one questions in parasitology, vector biology and invertebrate immunity, vertebrate host to another requires successful infection of a mosquito thereby bridging these disciplines. Training will consist of benchwork, vector, during the course of which the parasite undergoes complex attendance at research seminars, reading and discussion of the relevant differentiation and growth processes in association with diverse insect literature. Results will be presented at regular laboratory meetings as tissues. Interactions between parasite-encoded proteins and host molecules can critically influence Plasmodium viability and differentiation and well as inter-laboratory meetings involving members of the network. Young research fellows will conduct research in different network laboratories therefore the capacity of the vector to transmit malaria. The objectives as appropriate. In addition network members will attend specialised of the proposed research are to identify novel Plasmodium and Anopheles courses and international conferences. mosquito gene products which interact to facilitate tissue invasion, or play a role in host defence responses elicited by immune-recognition of parasite determinants. Stage-specific parasite genes which may affect viability within, or invasion of, specific host tissues will be isolated as well. Very little is known at the molecular level of mechanisms of Plasmodium parasite invasion and survival in mosquitoes. Basic information regarding these phenomena are needed for the initial development and refinement of malaria control strategies targeted towards interruption of disease transmission at the level of the vector.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'ALGAL biorefinery of biogas digestate to high VAlue fuNctional IngredientS through circular approachEs' (ALGALVANISE).

assistant: **Concept**

The anaerobic digestion (AD) industry is currently facing serious environmental and economic challenges due to the restrictions on the usage of digestate (the slurry residue of the process), coupled with reductions in subsidies for biogas production. It is important for the biogas industry to shift towards an AD biorefinery approach to make valuable co-products from the digestate fraction while recovering nutrients. Algae is an efficient tool for recovering the nutrients due to its ability to assimilate the nutrients efficiently while producing biomass rich in proteins, lipids, carbohydrates, vitamins, and minerals. However, there are no relevant commercially-operating algal digestate treatment plants due to the high energy inputs required for producing and harvesting the algae. ALGALVANISE will advance the state-of-the art by developing two novel concepts: 1) enzyme-assisted enhanced algal cultivation; and 2) combinatorial bioflocculation using bacteria and biopolymers. These two processes are targeted towards efficient nutrient recovery by algae from the digestate and harvesting high-quality algal biomass to produce high-value functional ingredients. The proposed body of research involves extensive training of the hosted researcher in the development of skills that will have a clear positive impact regarding her professional development and career opportunities. It is expected that ALGALVANISE will enable the Researcher to progress significantly with regards to her career goals, a primary one regards being an independent researcher that can develop commercially-relevant high-impact research projects that develop and demonstrate innovations that can ultimately be deployed at flagship facilities. The innovations developed in ALGALVANISE could themselves ultimately lead
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'FoodSafetyGuardian: Using digital solutions to lower the risk of foodborne illnesses' (Novo).

assistant: **Concept**

Stricter food safety laws have been/are being implemented around the globe to minimise largely preventable foodborne diseases that currently afflict over 600 million people a year. A major challenge in verification processes is the inability to guarantee a finished food product is pathogen free. By monitoring and verifying the parameters that have been set are actually effective during food manufacturing, companies can minimise microbial risk. Accordingly, Novolyze is developing FoodSafetyGuardian (FSG) - the first cloud-based software solution that integrates with equipment already in place at manufacturing plants, to collect data in real time for continuous analysis. FSG uses algorithims to determine if a change in set parameters (e.g. a specified temperature) should trigger an alarm or whether it is not a risk at the specific stage of food processing. FSG is the first platform that performs this level of analysis in real time. It also allows for add-ons such as a hygiene monitoring platform (HMP) to analyse cleaning and sanitation operations within a factory environment.The aim of this EIC project is to complete development of software for FSG and the HMP and then test it amongst customers. These products are expected to streamline and transform the food safety market. Novolyze aims to take FSG and the HMP to TRL8. Following commercialisation activities post-EIC, both products will be ready for market entry. Novolyze then aims to dominate an estimated total, global addressable market, valued at EUR 457m by 2023. The company has grown its organisation to ensure they have the expertise and competencies with the team to complete development in the EIC project and eventually launch the products on the market. This will lead to accelerated growth for the company. The curr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'To develop a cost-effective, fast-to-deploy, low-power and flexible video surveillance system that automatically combines images from multiple cameras to create a 180˚ panoramic view.""' (CHAMELEON) targeting Seventh Framework.

assistant: **Abstract**

The main aim of the CHAMELEON project is to develop a cost-effective, fast-to-deploy, low-power and flexible video surveillance system that automatically combines images from multiple cameras with overlapping regions to create a natural seamless panoramic view of the monitored area.CHAMELEON will be a flexible CCTV system allowing for fast and cost-effective deployment. In cases where a wired solution would be feasible, CHAMELEON will interface with the Internet network using the Ethernet communication protocol. In scenarios like remote surveillance, CHAMELEON will use a low-power and secure 5GHz Wireless LAN IEEE 802.11a connection to transmit real-time video signals to the monitoring station. CHAMELEON will implement two layers of security protocols – Data encryption after encoding and authentication at the network layer. CHAMELEON will use a very low power and light-weight video compression algorithm with low bit rates. This will make it possible for the system to be battery operated for a longer time, making it ideal for Temporary Monitoring. CHAMELEON is ideal for Temporary Monitoring since it can be connected to a wireless link, can be battery operated, fast-to-deploy and is able to quickly and automatically configure a network. CHAMELEON will improve the quality of CCTV video display by combining images from multiple cameras with overlapping regions to create a natural seamless panoramic view of the monitored area. CHAMELEON can be used to feed existing Intelligent Video Surveillance systems with wider-view (panoramic) video, therefore increasing their efficiency and detection rate.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Functional ecology of the plant-fungus interface: Harnessing evolutionary genomics, transcriptomics and experimental ecology to dissect communication and nutrient exchange in a mutualistic symbiosis' (OakMycEvo).

assistant: **Concept**

This proposal aims to construct an evolutionary framework for the molecular interactions between ectomycorrhizal fungi and their plant hosts. Ectomycorrhizal (ECM) symbiosis is a mutualistic association between fungi and trees that is founded on reciprocal exchange of nutrients, facilitating growth in nutrient-limited or otherwise stressful environments. The symbiosis has evolved independently in many fungal clades, raising questions about its evolvability and the ecological redundancy of different ECM fungi. The ability of one ECM fungus to functionally replace another is especially salient in light of environmental change and loss of biodiversity. What components of communication between fungus and plant are conserved among ECM species? How conserved are molecular interactions at different phylogenetic scales? What are the molecular mechanisms responsible for phenotypic variation? ECM fungi from the genus Amanita will be grown together with the host Quercus robur (pendunculate oak). Q. robur displays endogenous rhythmic growth with alternating root and shoot flushes, distinct physiological states of growth that influence interactions with ECM fungi. The fungal strains are selected to survey variation i) between different Amanita ECM species and ii) in comparison with closely related saprobic Amanita sp., using a phylogenomic approach. We will profile genes expressed on both fungal and plant side at different time points: during mycorrhizal development and in mature mycorrhizas, while separating each time point into periods of root flush and shoot flush. We will profile a compendium of traits related to the functioning and success of ECM symbiosis at each developmental stage. Together these results will allow us to develop a detailed mechanistic view of the genes and p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Uncovering the biological relevance of the replication-associated protein splicing during viral replication in geminiviruses and other CRESS viruses', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Due to their limited protein-coding capacity, viruses have evolved sophisticated mechanisms to hijack the host molecular machinery for their own benefit; among these strategies, splicing of the viral transcripts allows them to increase their transcriptome and proteome diversity, and has been described in several virus families, including plant DNA viruses, such as geminiviruses. Geminiviruses, which cause devastating problems for the agriculture worldwide, belong to the circular, replication-associated protein (Rep)-encoding (CRESS) viruses, a phylum infecting organisms from all three domains of life and potentially sharing analogous mechanisms for genome replication. Importantly, Rep is the only protein required for viral replication, and is structurally conserved across CRESS viruses. Splicing of Rep transcripts has been anecdotally reported in circoviruses and a few minor genera of geminiviruses, with some splicing events required for a full infectivity. On the other hand, unpublished work in the host group has uncovered that i) Rep from different begomoviruses, the major genus within the Geminiviridae family, associate with the plant splicing machinery; and ii) tomato yellow leaf curl virus (TYLCV) Rep transcripts are spliced during the infection, giving rise to at least five unknown Rep protein isoforms, lacking either the oligomerization domain or part of the N-terminal DNA binding domain. We propose to uncover the importance of Rep splicing in TYLCV and to establish its relevance during the viral replication, by characterizing Rep spliced variants interactome and functions. We will also analyze the conservation of Rep splicing landscape in different geminiviruses and CRESS viruses, potentially outlining an unknown layer in the regulation of the replication of the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Multiscale Applications on European e-Infrastructures' (MAPPER).

assistant: **Innovation**

Today scientists and engineers are commonly faced with the challenge of modelling, predicting and controlling multiscale systems which cross scientific disciplines and where several processes acting at different scales coexist and interact. Such multidisciplinary multiscale models, when simulated in three dimensions, require large scale or even extreme scale computing capabilities. Progress in science and technology is limited by our ability to solve efficiently such problems on available distributed computing infrastructures. The MAPPER project will respond to this critical need by developing computational strategies, software and services for distributed multiscale simulations across disciplines, exploiting existing and evolving European e-Infrastructure. Driven by seven challenging applications from five representative scientific domains (fusion, clinical decision making, systems biology, nano science, engineering), MAPPER will deploy a computational science environment for distributed multiscale computing on and across European e-infrastructures. By taking advantage of existing software and services, as delivered by EU and national projects, MAPPER will result in high quality components for today's e-Infrastructures. We will advance the state-of-the-art in high performance computing on European e-Infrastructures by enabling distributed execution of multiscale models. We will develop tools, software and services that allow two modes (loosely - and tightly coupled) of multiscale computing, in a user friendly and transparent way. We will integrate our applications into the MAPPER environment, and we will demonstrate their enhanced capabilities by answering one challenging scientific question related to each application. We plan to collaborate with other projects on ada
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Cryopreservation of marine planktonic crustacean nauplii for innovative and cost-effective live feed diet in fish juvenile aquaculture' under Horizon 2020.

assistant: **Concept**

The SME Planktonic has succeeded in cryopreserving marine crustacean nauplii (hereafter called CryoProduct) in large user-friendly entities, and to revive them as live individuals after thawing. The ease-of-use CryoProduct meets the nutritional requirements of fish larvae. A doubling in growth rate and a 25-30% shortening of the live feed period compared to a diet of the suboptimal live feed diets commonly used at marine hatcheries have been demonstrated (large-scale industrial trial, TRL6). With a well-functioning feeding protocol to be developed in the project period, it is expected that performances of the fish larvae will be even better. It will be put effort on optimizing the cryopreservation protocols to achieve a CryoProduct with even better quality than today for improving the performances of fish juveniles. A bio-security evaluation will be performed, and a screening of microorganisms will be needed for the registration of the CryoProduct. To successfully launch the CryoProduct into the EU market, it will be of major importance to scale up the production, to establish efficient logistic systems, identify end-users needs and to provide a reliable commercialisation plan for the best possible market introduction. As the CryoProduct has outstanding performances compared to today’s alternatives, we expect a market share of 50% of the live feed market on a longer term. This corresponds to a revenue of more than 100 million €. As the market grows 3-4% per year, the market size will double in about 20 years. It is a considerable aquaculture production in the EU. If the product meet the expectations, it will most probably be a major contribution to realize the production potential of marine fish in aquaculture in the EU. This will result in many thousand new jobs, and p