RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Design, synthesis, Structural Characterization and biological evaluation of new peptidomimetics with a defined secondary structure'.

assistant: **Concept**

Protein-Protein interactions are fundamental to biology and constitute an interesting target class for medicinal chemistry projects investigating cell adhesion, signal transduction, proteolysis or protein folding diseases. With the deciphering of the human genome project, the next decades will bring a myriad of new proteins being potentially important receptors since they might be associated with diseases. To design ligands towards such receptors, peptides and peptidomimetics will play an important role, since they are known to display unprecedented structural and functional diversity. One challenging aspect of peptidomimetic chemistry is to develop a strategy, which results in molecules that adopt specific secondary structures relevant to those found in protein segments or substrate-bound peptides of interest. Despite numerous efforts, there are today only few success stories where chemists have redirected the complex nature of protein-protein interactions. So an important step in this effort is the development of molecular scaffold inducing conformational constraints.The research topic of the early stage research projects proposed by this network is to design, synthetise, characterise the secondary structure of new peptidomimetics of biological interest and finally to evaluate their biological activities. The aim of the present project is to build a model of training program in medicinal chemistry in order to create a very stimulating, international and interdisciplinary environment for the training of young res earchers at the early stage of their scientific career. The project gathers three academic groups with excellent expertise in various areas of chemical and medicinal chemical sciences: 1) Università dell'lnsubria - ltaly; 2) Université de Paris Sud - France ;
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Functional circuits mediating the effects of reward value on perception within and across sensory modalities' in the context of a Horizon 2020 call.

assistant: **Objectives**

Our perceptual system needs to maintain a balance between selectivity and sensitivity, so that redundant information is dismissed, but novel and important information does not go unnoticed. Selective attention and reward value are among mechanisms that adjust this balance, by exerting top-down control over bottom-up sensory processing. Excessive reliance on top-down signals has been suggested to underlie pathologic conditions, such as hallucinations. In contrast, controlled boosting of top-down signals is a potential tool to rehabilitate impaired sensory functions. Despite their importance, key aspects of top-down and bottom-up interactions have remained unknown: We do not know how abstract, non-sensory signals, such as reward value, could exert specific sensory effects; it is unclear how they are transmitted across sensory modalities and what the underlying neural mechanisms are. Here, I will try to provide answers to these questions by combining behavioural testing, neuroimaging, and non-invasive brain stimulation techniques in humans. I will use a novel approach, where abstract reward value of a stimulus is linked to a sensory modality label. This enables me to trace how value-driven, top-down signals are communicated to sensory areas and how they impact on different aspects of perception: from detection of external signals to perception of illusory associations. Using brain imaging techniques, I will distinguish between regions where the sensory modality label is represented, and regions where reward value signals are coded, regardless of their sensory modality. Finally, I will test whether non-invasive perturbation of regions containing sensory modality labels impairs perception in the respective modalities, thereby testing if these regions play a causal role in se
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Fostering the talents and knowledge of women scientists from the Enwise countries; recommendations' (ENWISE-CONFERENCE) targeting Sixth Framework.

assistant: **Abstract**

The vehicle for the dissemination of the results of the Enwise report will be a conference to be held in Tallinn, Estonia (proposed date September 9-10, 2004), with emphasis on participation by scientists from the Enwise countries, including decision-makers in research policy, in order to encourage debate on gender issues in research.The Enwise Report, launched in January 2004, was prepared by the Enwise Expert Group, which was set up by the European Commission in September 2002 to promote gender equality in science by addressing the situation of women scientists in CEEC and in the Baltic States. This conference will present an opportunity for scientists and research policy decision-makers from the Enwise countries, and also from the current Member States and the countries associated to FP6 to hear the results of the Report, to conduct a debate on the conclusions and validate its recommendations.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Actin-membrane interaction in biomimetic and living cellular systems studied with a novel, high precision optical method' to be submitted under Seventh Framework.

assistant: **Abstract**

The lethal potential of cancer is due to abnormal cell division and aggressive metastatic activity that turn resting cancer cells into motile structures which spread through an organism, resulting in numerous and often uncontrollably growing subpopulations. It is well known that both cell motility and cell division depend crucially on cell mechanics, namely on actin cortex. The actin cortex consists of a dense biopolymer network, steadily contracted by myosin motors. A key to understanding the abnormal motility and proliferation of cancer cells is the investigation and quantification of the physical properties of the actin cortex. Of special interest is the activity of the acto-myosin network and its interaction with the plasma membrane. This actin-membrane interplay is a major contributor to many physical properties of the whole cell. We propose a systematic study of acto-myosin membrane interactions using biomimetic and living cells in combination with a novel optical method that allows simultaneous manipulation and detection of the cell edge with high spatial and temporal resolution. Our main objectives are: a) to quantify the physics of the actin cortex in biomimetic cells; b) to understand the nonequilibrium statistical mechanics of active acto-myosin networks; c) to study of actin-membrane interactions in the cell cortex and the lamellipodium of living cells. The applicant and the host institute provide complementary skills for this project. The applicant has expertise in advanced optical detection methods, cell motility and stochastic processes, and the host institute will provide the biomimetic actin cortex system, expertise on biomimetics, active systems and biology and the interdisciplinary working environment, including biologists and biochemists, necessary f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Science in SEVEN ways' (SEVEN13) targeting Seventh Framework.

assistant: **Abstract**

“Science in SEVEN ways” will invite for the fourth year again the public to come, play, talk and learn about researchers. The event will take place in 7 major cities from all over Romania, in over 14 locations (research institutes, museums, shopping centers, public places, subway stations) and aims to reach 35000 qualitative interactions, over 100 researchers, students and teachers and over 300000 prs to be exposed to the awareness campaign. The awareness campaign will start from the first month, with a major component of the internet and social media tools. Also, a contest will be launched “2200 Science Lab” where individuals will work with researchers in order to promote their idea of the science lab in the year 2200. In this way we maintain the contact between the researchers and the new generation from various layers of society. The whole event of 2013 will be as a “SCIENCE MAP” where visitors will come and will be guided through various fields and types of experiences (demonstrations, experiments, games, interactive discussions). Although the public tends in this kind of events to discuss only scientific subjects, the personal side of the researchers will be highlighted through informal discussions, quizzes, Wanna be medals. In Bucharest, the event will be organized in several subway stations so that the public at large to be exposed to the concept. The logo of the previous years will be maintained as a theme in order to create a link with previous years and awareness of the European and national dimension of the event.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Non Uniform Hyperbolicity in Global Dynamics' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

An important part of differentiable dynamics has been developed from the uniformly hyperbolic systems. These systems have been introduced by Smale in the 60's in order to address chaotic behavior and are now deeply understood from the qualitative, symbolic and statistic viewpoints. They correspond to the structurally stable dynamics. It appeared that large classes of non-hyperbolic systems also exist. Since the 80's, different notions of relaxed hyperbolicity have been introduced: non-uniformly hyperbolic measures, partial hyperbolicity,... They allowed to extend the previous approach to other families of systems and to handle new examples of dynamics: the fine description of the dynamics of Hénon maps for instance.The development of local perturbative technics have brought a rebirth for the qualitative description of generic systems. It also opened the door to describe more globally the spaces of differentiable dynamics. For instance, it allowed recent progresses towards the Palis conjecture which characterizes the absence of uniform hyperbolicity by the homoclinic bifurcations — homoclinic tangencies or heterodimensional cycles. We propose in the present project to develop technics for realizing more global perturbations, yielding a breakthrough in the subject. This would settle this conjecture for C1 diffeomorphisms and imply other classification results.These past years we have understood how qualitative dynamics of generic systems decompose into invariant pieces. We are now ready to describe more precisely the dynamics inside the pieces. We propose to combine these new geometrical ideas to the ergodic theory of non-uniformly hyperbolic systems. This will improve significantly our understanding of general smooth systems (for instance provide existence and finitenes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Building European Communities' Resilience and Social Capital'.

assistant: **Concept**

The Sendai Framework  for Disaster Reduction 2015-2030 points out that global evidence indicates that in all countries the exposure of people and assets to disasters has increased faster than attempts to decrease vulnerability. The Framework underlines an all-society engagement, which addresses the most vulnerable groups, whilst accounting for contextual and cultural differences. It also calls for a more explicit focus on people, their health and livelihoods, and the local level, since individuals and local communities possess their own capabilities, networks, methods, tools and means to absorb impacts and bounce back. Thus, the ‘capital’ that is available at the root-level deserves to be recognised and incorporated in the policies and strategies for disaster risk reduction and enhancing of resilience. To improve the overall resilience of people, communities and thereby the whole society, the BuildERS project focuses on the most vulnerable individuals, groups and communities. Strengthening the social capital, risk awareness and preparedness of the most vulnerable segments of the societies and communities will increase understanding on what societal resilience comprises.  BuildERS will develop knowledge and insights that will device recommendations for policies, plans, strategies, and competencies for building partnerships, networks and trust for progressively fortifying the social capital and resilience against future threats, be they natural or man-induced. The special focus on communities and in particular on the most vulnerable groups answers to the so-far unfulfilled needs of these communities.BuildERS uses several research methods such as i) Stakeholder engagement with co-design and co-creation processes, ii) Field surveying and questionnaires, iii) Comparative res
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Enhancing the participation of Mediterranean countries in the area of Food Quality and Safety in Framework Programme 7' (2002-2006).

assistant: **Concept**

The overall objective of the MEDA GO TO EUROPE project is to raise the quantity and quality of research projects from participants as partners - particularly from Mediterranean Countries - in all types of instruments, in Thematic Priority 5 Food Quality a nd Safety" (TP5) of future FP7. Thereby, the project will ensure an increased number of successful participants for FP7 and foster the cooperation between research communities from Member States and Mediterranean Countries, thus contributing to the creation of a real European Research Area including Mediterranean Countries. This overall objective will be achieved by three major lines of activities: 1. capacity building and supporting a network of technical support organisations in Mediterranean Countries, and supporting the research communities in Mediterranean Countries with tailor-made information, assistance and services. 2. Organisation of match making between European and Mediterranean organisations 3. participating to the definition of Framework Programme 7 by taking into account the expectations of Mediterranean countries For the implementation, a workplan consisting of 7 workpackages has been put together, including Mapping of partners, Training for support organisations and for researchers, Exchange of experience & expertise, Match-making, Preparation of the Framework programme 7, Dissemination and networking activities, and Management. In order to fulfil these objectives, a project consortium consisting of 16 partners from 12 countries has been set up. These partners are representing Mediterranean Countries (8), EU Member States (6) and Candidate states (2) and have a profile of technical support. The MEDA GO TO EUROPE project is relevant to the objectives of Thematic Priority 5, since it will s upport the pa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The analysis of geometric non-linear wave and kinetic equations' to be submitted under Horizon 2020.

assistant: **Abstract**

The present proposal is concerned with the analysis of geometric non-linear wave equations, such as the Einstein equations, as well as coupled systems of wave and kinetic equations such as the Vlasov-Maxwell and Einstein-Vlasov equations. We intend to pursue three main lines of research, each of them concerning major open problems in the field.I) The dynamics in a neighbourhood of the Anti-de-Sitter space with various boundary conditions.This is a fundamental open problem of mathematical physics which aims at understanding the stability or instability properties of one of the simplest solutions to the Einstein equations. On top of its intrinsic mathematical interest, this question is also at the heart of an intense research activity in the theoretical physics community.II) Non-linear systems of wave and kinetic equations. We have recently found out that the so-called vector field method of Klainerman, a fundamental tool in the study of quasilinear wave equations, in fact possesses a complete analogue in the case of kinetic transport equations. This opens the way to many new directions of research, with applications to several fundamental systems of kinetic theory, such as the Einstein-Vlasov or Vlasov-Maxwell systems, and creates a link between two areas of PDEs which have typically been studied via different methods. One of our objectives is to develop other potential links, such as a general analysis of null forms for relativistic kinetic equations.III) The Einstein equations with data on a compact manifold. The long time dynamics of solutions to the Einstein equations arising from initial data given on a compact manifold is still very poorly understood. In particular, there is still no known stable asymptotic regime for the Einstein equations with data given on a sim
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Anomaly Detection combining time series and unstructured data using AI/ML algorithms in a distributed cloud/edge device scenario', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

IoT has taken the world by storm and in 2025 there will be ~75Bn connected devices, creating an amount of data never generated before. This comes with a new set of challenges, which need to be addressed with regards to IoT device management, especially in industrial settings. Currently, there are limited tools for embedded Linux IoT device management (e.g. cameras, sensors, thermostats, routers, etc), which are not able to effectively manage the devices and keep the IoT infrastructure secure.QBee offers the qbee.io platform, a unique embedded Linux automation, provisioning and security tool enabling a highly efficient IoT device management with high security focus for the overall IoT infrastructure. With the SmartAD project, QBee targets the development of an innovative module to the platform, namely an automated smart, accurate and secure anomaly detection module, which was identified as top priority to disrupt the IoT devices management tools. Intelligent algorithms can be used for detection of malfunctioning/suspicious behavior using advanced anomaly detection, fingerprinting and the awareness of configuration changes that the device should adhere to. To achieve this, time series data as well as file and configuration changes needs to be analyzed.Although, QBee has a strong team in the area of  full-stack development, system administration, embedded devices (Linux), automation and cloud software scaling, which allowed to bring the product to a beta-version, it is also very small, and currently QBee does not have in-house skills for the next innovation stage, where forefront Artificial Intelligence/Machine Learning  and data analytics skills are demanded. The SME Innovation Associate Programme fits the QBee plan on boosting R&D activities and the recruitment of an Inn
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Reliable, real-time process monitoring solutions for gold mines to reduce costs, reagent use and increase gold production'.

assistant: **Objectives**

Gold mines lose $5B in recoverable gold each year because they can’t control their process efficiently. Having the right amount of cyanide is the single most critical parameter in the gold extraction process. Furthermore, cyanide costs are the main cost driver for mines and often exceed 70% of the total processing costs. Without reliable and real-time cyanide monitoring tools, mines face high operating costs and losses in gold production. Our Solution, CyanoSmart, is a mobile, IoT read-out device that uses single-use test cartridges to detect cyanide. Operators can use our handheld devices anywhere in the mine and get a result on the spot. Integrated into the Cyano.AI cloud, mines can visualise their cyanide levels in real time online. Our data-driven, connected monitoring system helps mines optimise their gold extraction process, while reducing operating costs, minimising their environmental footprint and eventually achieve the UN SDG goal 12 for their industry. Thanks to our patented molecule and AI-based measurement algorithm, our technology excels in providing a reliable, reproducible result where other technologies regularly fail.With this proposal, we want to develop the CyanoSmart to scale for the benefit of the entire gold mining industry and community, and contribute to transforming mining into a more transparent and more efficient industry.