RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Dissecting dsRNA uptake in RNAi-based antiviral immunity' (DDRR) under Horizon 2020.

assistant: **Objectives**

Important viral infectious diseases, such as dengue and chikungunya, are transmitted to humans by insectvectors. One of the key factors that modulates whether an insect is competent or not to transmit a givenpathogen is its innate immune response. The major antiviral defense in insects is the RNA interference(RNAi) mechanism that is activated by the detection of viral double-stranded RNA (dsRNA). Duringantiviral RNAi a silencing immune signal is transported from one cell to another to set an antiviral state(systemic RNAi). To be primed, non-infected cells must sense this silencing signal and internalize it.Although dsRNA as a mediator of local antiviral immunity is well established in insects, the effectors of asystemic immune response are not identified. For instance, the identification of the dsRNA receptor ininsects remains elusive. This proposal intends to dissect the mechanism of dsRNA uptake in insects withspecial focus on discovering its receptor. I propose to combine functional (genome wide RNAi screen, invivo dsRNA oral uptake) with binding (electrophoretic mobility shift assay, surface plasmon resonance) andstructural assays (expression, production and studies of complexes receptor/dsRNA) using Drosophilamelanogaster as insect model and an array of viruses in order to identify and characterize the dsRNAreceptor.To be found, the manipulation of this receptor could help control the insect vectors of emergingviral diseases. Understanding how the infection is controlled within the insect before crossover to the humanhost could generate new strategies to disrupt pathogen transmission.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Foreign aid and stability in the Middle East' to be submitted under Seventh Framework.

assistant: **Abstract**

The overall objective of the proposed research training is to restart Beata Paragi’s career after her maternity leave and advance its development by gaining work experiences and enhancing the diversity of her skills and competences at Fafo AIS, an independent research institute in Norway. The training will strengthen the ‘researcher’ part of her academic identity building on her teaching experiences. It will help the fellow reach professional maturity as a researcher enhancing the transfer of knowledge between a research organisation operating in the field of social sciences and the fellow who has worked as an assistant professor at a Hungarian university.Objectives will be achieved  by means of empirical research on recent events taking place in the Middle East. The research project embraces the issue how relations between the Middle East and the West (with particular emphasis on the EU) have been changing in a broad sense and more narrowly in the Israeli-Palestinian conflict. The project contends that an important component of these relations has been the trade-off between the foreign support channelled in the form of aid to governments in the Middle East and benefits (regional stability, regime stabilities) ensured for such support. The research aims (1) to track the recent changes of Western (EU, to lesser extent US) aid policies in the MENA countries involved in the Israeli-Palestinian conflict and how they are applied in an attempt to control regional developments; (2) to understand local perceptions on aid-related foreign interventions and on political elites and/or regimes (3) to understand how Western aid policies have contributed to the Arab Spring and how the focus of Western aid has been changing; to evaluate the function and overall ‘price’ of foreign aid –
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'FEMTOSECOND LASER PRINTER FOR GLASS MICROSYSTEMS WITH NANOSCALE FEATURES' to be submitted under Seventh Framework.

assistant: **Abstract**

FEMTOPRINT is to develop a printer for microsystems with nano-scale features fabricated out of glass. Our ultimate goal is to provide a large pool of users from industry, research and universities with the capability of producing their own micro-systems, in a rapid-manner without the need for expensive infrastructures and specific expertise. Recent researches have shown that one can form three-dimensional patterns in glass material using low-power femtosecond laser beam. This simple process opens interesting new opportunities for a broad variety of microsystems with feature sizes down to the nano-scale. These patterns can be used to form integrated optics components or be ‘developed’ by chemically etching to form three-dimensional structures like fluidic channels and micro-mechanical components. Worth noticing, sub-micron resolution can be achieved and sub-pattern smaller than the laser wavelength can be formed. Thanks to the low-energy required to pattern the glass, femtosecond laser consisting simply of an oscillator are sufficient to produce such micro- and nano- systems. These systems are nowadays table-top and cost a fraction of conventional clean-room equipments. It is highly foreseeable that within 3 to 5 years such laser systems will fit in a shoe-box. The proposal specific objectives are: 1/ Develop a femtosecond laser suitable for glass micro-/nano- manufacturing that fits in a shoe-box 2/ Integrate the laser in a machine similar to a printer that can position and manipulate glass sheets of various thicknesses 3/ Demonstrate the use of the printer to fabricate a variety of micro-/nano-systems with optical, mechanical and fluid-handling capabilities. A clear and measurable outcome of Femtoprint will be to be in a situation to commercialize the ‘femtoprinter’ th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Precise Higgs Properties in the LHC Era' (HiggsEFTatNLO).

assistant: **Concept**

The observation of the Higgs boson at the LHC in 2012 was a defining moment for particle physics in the 21st century. As a result of this groundbreaking discovery, one of the top priorities of the European Strategy for Particle Physics is a programme to ""measure this particle’s properties with the highest possible precision"", in order to uncover the nature of electroweak symmetry breaking. The central role of the Higgs boson in this phenomenon, for which we have no dynamical explanation, means that many questions can be answered about physics beyond the Standard Model through the study of this particle at colliders. Effective Field Theory is the most general way in which departures from SM expectations are parametrised and forms a core part of the LHC physics programme.    In this proposal, I develop a strategy to incorporate recent developments in higher order calculations for EFT into global fits to high energy collider data with a particular focus on, though not limited to, Higgs physics at the LHC. I investigate the incorporation of Quantum Chromo Dynamics corrections interfaced with parton shower and hadronisation along with the effects of renormalisation group mixing of the Wilson coefficients. I will deliver a software package for efficient translation between different EFT descriptions, providing both a connection to other high energy physics tools for EFT, a framework for the analysis and interpretation of the global fits and an implementation of operator mixing within this framework. These elements will combine to extract maximum information from existing collider data in terms of limits on EFT coefficients and their interpretations in the context of UV models, paving the way for the study of EFT at the LHC and future colliders.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Targeting signals essential for angiogenesis' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Angiogenesis, the development of new blood vessels by sprouting occurs in the adult mainly during wound healing, but is also observed in tumours and ophthalmic or rheumatic diseases. The recruitment of new capillaries by solid tumours is important for the malignant process since the expansion of the selective absolutely depends on this process and the density of the vessels determines the metastasis potential. We propose here to investigate the signals by which four key proteins of endothelial cells, the cells forming the inner layer of blood vessels, control the proliferation, migration and capillary formation. Essential signalling mechanisms triggered by these proteins will be defined at the molecular level and potential target molecules for inhibition of angiogenesis identified. Making use of the recent developments of gene therapy vectors and liposome's, potential inhibitors of these proteins will be evaluated in selective angiogenesis models.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Flexible Wood Supply Chain'.

assistant: **Objectives**

A number of studies indicate that the market demand for wood will lead to strong competition between the different wood industry branches. This is especially true in view of a globalised wood market, in which production is characterised by fast structural changes and concentration processes. Competition between different wood industries and the development towards large production units, as well as an often highly diversified forest owner structure, demands a flexible delivery of varying wood quantities and quality. This leads to high cost, which weakens the position of the European wood industry within a global market. In addition, hazardous environmental events, such as wind throws, forest fires or beetle attacks, have increased during the past years. There is strong evidence that hazardous environmental events will become even more frequent, leading to unforeseeable damage in forests and to excessive felling. Increased competition, natural risks and political and economical disturbances within a global market undermine the concept of a steady and predictable long term development of the forest sector. The challenge is to improve existing processes of the wood supply chain to the needs of wood industry under these changing conditions. In order to meet the market demands of an improved and flexible wood supply chain, novel logistic concepts must provide better information assessment on wood resources and enhance optimisation models. The proposed project would provide a better and faster response to the demands of the different wood industry branches, which will lead to an increase in value recovery.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'GMES pre-operational security services for supporting external actions' under Seventh Framework.

assistant: **Concept**

According to the potential application areas identified under SEA (GMES Security working group in Support to External Actions), and the experience gained by the proposal consortium in Security and Emergency precursor projects (LIMES, G-MOSAIC, SAFER) this proposal will identify and exploit a set of Services able to provide reliable support to the EU External Action service and suitable to be integrated in the user working environment in an effective and reliable way.The proposal research and development focus will be on the enhancement of Crisis Management Response Services in rush and non-rush mode and in covering the relevant gaps identified in the perspective of a (pre-)operational approach.Reference Users for the service/products will include the main actors and stakeholders involved in the context of EU Missions and Operations in support to External Actions: European Union – EEAS (European External Action Service), EDA (European Defence Agency), National Institutions such as Ministries of Foreign Affairs and Ministries of Defence, Police Offices, Intelligence Centres, and also international institutions as UN bodies.The proposal aims to: (a) Demonstrate the effective contribution of an integrated geo-spatial service concept  to respond to the needs in SEA user-driven scenarios providing the User Community with an evolving  set of security service/products. (b) Involve the main User organization in the GMES Security domain in the use of the provided services. (c) Assure the continuity of the work done in previous GMES projects specifically on security and emergency domains. (d) implement synergies with the other GMES projects and initiatives (e.g. EU, ESA, EDA contexts) running in parallel with the project lifecycle. (e) Perform a comprehensive benefits analysis tak
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'a Stable and resilient ATM by integrating   Robust airline operations into the network' to be submitted under Horizon 2020.

assistant: **Abstract**

One of the key enablers of Trajectory Based Operations (TBO) is the automated updating of trajectories in reaction to developing uncertainties. However, a high frequency of updates and modifications leads to degraded system stability. The overall goal of START (a Stable and resilienT ATM by integrAting Robust airline operations into the neTwork) is to develop, implement, and validate optimisation algorithms for robust airline operations that result in stable and resilient ATM performance even in disturbed scenarios. START’s goal shall be reached by a suitable combination of methods from applied mathematics, i.e.: mathematical optimisation, optimisation under uncertainty, Artificial Intelligence (AI) and data science, as well as algorithm design. Furthermore, insight into the uncertainties relevant in TBO systems will be gained through simulations. The main focus of the project is the optimization of conventional traffic situations while considering disruptive weather events such as thunderstorms.  Specific goals include:1.To model uncertainties at the micro (trajectory) level, assimilate observations (via ADSB/Radar) every 15 min and propagate trajectory uncertainties using assimilated models and a stochastic trajectory predictor. 2.To model uncertainties at the macro (ATM network) level, assimilate observations (satellite data for storm, and network status) every 15 min., and propagate ATM network uncertainties using the assimilated models. 3.To develop an Artificial Intelligence (AI) algorithm capable of generating a set of pan-European (i.e., considering the whole traffic over Europe) robust trajectories that make the European ATM system resilient when facing these relevant validate ties. 4.To implement those algorithms as an advanced fight dispatching demo functiona
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Multimodal Agents Grounded via Interactive Communication'.

assistant: **Concept**

One of the main goals of artificial intelligence is to build artificial agents that can interact with humans using natural language. To fully master language, an agent needs to know how to use it to accomplish a goal; to interact with another speaker; and to refer to objects in the external reality. My research project aims at equipping an artificial agent with all these skills in one single learning framework.Communication helps humans accomplish things in the world and cooperate with each other, resulting in continuous and incremental updating of the speakers’ knowledge state. However, traditional machine learning methods used to model language are based on static and passive regimes, and are typically not grounded in external reality. I propose a radically different research programme, based on recent advancements in training neural networks using reinforcement learning, that will enable the move from a static, fully supervised to a dynamic, interactive learning where the agents need to use language to accomplish a task in the visual world. This will dramatically accelerate the development of machines that can talk with humans.Even though I am an established researcher in computational linguistics, with substantial contributions to the integration of language and vision, I still need to fully develop my own line of research to become a leading, independent researcher in Europe. Carrying out the present proposal at Universitat Pompeu Fabra and Facebook Artificial Intelligence Research will be a fundamental step towards achieving my goal, since my hosts are leaders in computational linguistics, machine learning, and artificial intelligence in general, and specifically in the methods needed for the present proposal. Conversely, my unique profile, bridging computational
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Active and biodegradable multilayer structure for dehydrated or dried food packaging applications'.

assistant: **Concept**

Dried food has many advantages when compared to other foods: cheaper transportation costs, longer storage life and ease of use. Demand of these foods is forecast to growth, reaching 148Mton globally during 2016. Dried baby food market reflects this trend, as parents have decided to satisfy nutrient requirements of a child using commercial food. This growth is translated to a huge production of packaging and associated wastes.Modified Atmosphere Packaging (MAP) is a preserving technique usually applied in dried food. Applications are commonly based on multilayer plastic materials. However, there is no cost-effective and proven technology capable of fully recycling these materials. A 5% substitution of these materials using Modified Atmosphere Packaging (MAP) applications would reduce over 300.000 tons of non renewable plastic packaging wastes disposal .The use of bio-based materials is a promising alternative in the packaging industry to reduce the disposal and the use of non-renewable resources.BIOACTIVELAYER consortium will develop a multilayer biodegradable structure that can provide a sustainable and more environmentally friendly alternative to materials currently used in MAP.BIOACTIVELAYER solution will provide a novel biodegradable multilayer structure based in paper for dried baby food packaging. Paper properties will be enhanced following a three steps approach. 1) To increase paper moisture barrier, blends of waxes and resins will be applied. 2) Main moisture barrier improvement will rely on a composite based in PHA. PHA lacks of the barrier required for MAP applications. Therefore,  composites with mineral fillers will be developed to obtain a moisture barrier layer. 3) Oxygen barrier materials will be improved through use of oxygen scavenging compounds.A whole
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Smart Cholesterol-Mopping Polymer Nanoparticles in Niemann-Pick Disease Type C' (NanoMop) targeting Horizon 2020.

assistant: **Abstract**

Niemann-Pick Disease Type C (NPC), also known as “childhood Alzheimer’s”, is a rare genetic disorder caused by the accumulation of cholesterol particularly in the brain with subsequent cognitive and mobility decline. In the EU NPC has an incidence of 1 per 100,000 people. Most cases are detected during childhood and progress to cause life-threatening complications by the second or third decade of life. Cyclodextrins (CDs), a family of naturally occurring sugars, have recently gained considerable attention as a potential therapeutic intervention in the treatment of the disease because of their capacity to sequester cholesterol. Although promising, the current treatment of NPC based on a chemical modification of bCD suffers from poor pharmacokinetics and bioavailability in the brain. In this project I propose a new interdisciplinary approach in which bCDs will be embedded into a novel class of smart polymer nanoparticles (NanoMops) that could overcome these limitations. The project addresses an important question that needs to be answered urgently and its successful completion will contribute to the treatment of the neglected disease in line with the Horizon2020 health goal of providing better and more effective therapies. My specific skillset in chemical modification of CDs puts me in a unique position to successfully carry out this project. This interdisciplinary proposal is designed to provide me with advanced training in macromolecular chemistry and in a range of cutting-edge biological techniques. The fellowship will significantly diversify my competences and broaden my profile – professionally and personally - enabling me to pursue a career as an internationally recognised independent researcher. The project will also create new important international and inter-sec