RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'De novo formation of the generative plant meristem in 4D' (DeNovoMeristem) targeting Horizon Europe.

assistant: **Abstract**

Meristem formation is essential for continuous and organised growth in all land plants. The meristem is a multicellular generative centre that produces the plant body and is maintained by spatially restricted gene expression domains throughout a plant’s lifespan. However, little is known about how these stable patterns are established de novo from a single cell. This is because embryonic meristem formation in flowering plants is enclosed within the seed and fruit and therefore live imaging, chemical treatments and gene interaction studies are technically difficult. The bryophyte Marchantia polymorpha has emerged as a powerful model to investigate meristem formation in real time. The single-celled Marchantia haploid spore is exposed and undergoes defined patterns of cell division to ultimately produce a highly organised meristem.  In the proposed project, spatial and temporal gene expression changes will be observed live during meristem formation, and the molecular interactions driving these changes will be identified. As well as revealing how gene expression patterns and feedback loops can form de novo, this work will reveal key innovations during meristem evolution and identify the fundamental requirements for meristem formation in land plants.


**Keywords:** Plants, meristems,  stem cells, patterning, gene expression, Marchantia, spores
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Federation for FIRE' under Seventh Framework.

assistant: **Concept**

A federation of experimentation facilities will significantly accelerate Future Internet research. Fed4FIRE will deliver open and easily accessible facilities to the FIRE experimentation communities, which focus on fixed and wireless infrastructures, services and applications, and combinations thereof. The project will develop a demand-driven common federation framework, based on an open architecture and specification. It will be widely adopted by facilities and promoted internationally. This framework will provide simple, efficient, and cost effective experimental processes built around experimenters' and facility owners' requirements. Insight into technical and socio-economic metrics, and how the introduction of new technologies into Future Internet facilities influences them, will be provided by harmonized and comprehensive measurement techniques. Tools and services supporting dynamic federated identities, access control, and SLA management will increase the trustworthiness of the federation and its facilities. A FIRE portal will offer brokering, user access management and measurements. Professional technical staff will offer first-line and second-line support to make the federation simple to use. The project will use open calls to support innovative experiments from academia and industry and to adapt additional experimentation facilities for compliance with Fed4FIRE specifications. A federation authority will be established to approve facilities and to promote desirable operational policies that simplify federation. A Federation Standardization Task Force will prepare for sustainable standardization beyond the end of the project. The adoption of the Fed4FIRE common federation framework by the FIRE facilities, the widespread usage by both academic and industrial expe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Performance-Art in Eastern Europe (1950-1990): History and Theory' in the context of a Seventh Framework call.

assistant: **Objectives**

The aim of this project is to provide, for the very first time, an overview of the historical and transnational development of performance art (performances, actions, happenings) in Eastern Europe during the dictatorship period. Performance art shall not only be presented as an object of study, but also as a central art genre implicitly and explicitly involved both in the investigation of cultural practices and in the creation of alternative ways of action. The project focuses, for one, on the artistic exploration of totalitarian or real-socialist practices, rituals, and gestures, but also on artistic ways of action developed in the course of underground activity. Eastern European performance art came to life under conditions in which it was from the very start considered as dubious both aesthetically and contentwise. However, tolerance, hindrance, and sometimes even prohibition led to a heightened degree of self-reflection, minimalism, abstraction, and analysis; in other words, to characteristics representative of the specificity of East European performance art between 1950 and 1990.At the same time, the proposed project is to be understood as an archaeological one, for it sets out to reconstruct correlations and interactions between unofficial artistic production and official cultural practice. Moreover, it aims to make available to a broader public artistic endeavours that until now could not be centred on in research fields like art history, theatre-, and cultural studies in an Eastern European context.The project will concentrate on the following four research areas:1. Territorial interrelationships (between the Eastern European countries, between East and West)2. Specificity of practice in Eastern European performance art (subversive affirmation, minimalism, abst
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Delivering Hydroacylation: A General and Enantioselective Process' (DEGENHA), addressing dissemination and exploitation.

assistant: **Impact**

This proposal outlines the development of a suite of truly general hydroacylation catalysts that demonstrate high levels of functional group tolerance, enantioselectivity, broad applicability and ease of use in the laboratory. These advances will be achieved by the development of a new modular ligand system, based on the small-bite angle hemilabile diphosphines. By achieving these advances hydroacylation will become a general and robust disconnection for the synthesis of fine and bulk chemicals, new materials and target molecules.


**Keywords:** Hydroacylation, enantioselective, alkene, chiral phosphine
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Fracture mechanics based embrittlement modelling' to be submitted under Fifth Framework.

assistant: **Abstract**

FRAME project is initiated by 5 companies from 4 European countries under the umbrella of AMES network. The project initiates the development of fracture mechanics based irradiation embrittlement trend curves. Current assessment of the irradiated material condition is based on index temperature procedure, the reliability of which can be estimated only semi quantitatively. The created data will be compared with the current Charpy-V based trend curves. As cleavage initiation fracture toughness is the required property in the vesel safety analyses, the new approach will lead to more relevant condition assessment. Accurate and relevant material properties are required when the safety margins of the ageing plants will narrow. The new approach will be directly applied in the plant life management and plant life extension of the operating nuclear plants.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Treatment and prevention of bacterial infections by anti-adhesion compounds' (POLYCARB) targeting Fifth Framework.

assistant: **Abstract**

To combat the growing number of antibiotic-resistant bacteria new therapeutic strategies are needed. Our proposal aims to create novel therapeutics that can interfere with the adhesion of pathogenic bacteria to carbohydrate ligands present on target tissues. For many bacteria this event is the first and crucial step that leads to an infection. Since multiple copies of the bacterial receptors are present the optimal strategy is to use multiple copies of the carbohydrate, i. e. multivalency. This strategy can lead to dramatically enhanced binding compared to monovalent interactions. The specific carbohydrates will be synthesised chemically and will be coupled to novel multivalent backbone molecules. The molecules are evaluated in various adhesion assays and their applicability will be evaluated with relevant animal model studies. Our target pathogenic bacteria are H. pylori, E. coli, and S. suis.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Drought-tolerant yielding plants' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

DROPS will develop novel methods and strategies aimed at yield maintenance under fluctuating water deficit and at enhanced plant water-use efficiency. We deal with high genotype x environment interaction in the field (any trait can have positive, negative or no effect depending on drought scenarios) with an approach combining Physiology, Genetics, field testing and Ecophysiological modelling. The project targets four traits : seed abortion, vegetative growth maintenance, root system architecture and transpiration efficiency. It deals with maize and durum wheat, plus bread wheat and sorghum for specific tasks. DROPS will: - Develop new screens for identifying drought tolerant genotypes, from phenotyping platforms to the field with indicators which are (i) stable characteristics of genotypes with high heritability in phenotyping platforms (ii) based on novel knowledge (e.g. combinations of metabolite concentrations, sensitivity parameters of models or hormonal balances) (iii) genetically related to target traits and able to predict genotype performance in the field via simulation and/or statistical models. - Explore the natural variation of the four target traits by (i) linking the target traits to physiological pathways, genes or genomic regions (ii) assessing the effects of a large allelic diversity for the four target traits via association genetics. - Support crop improvement strategies by developing methods for estimating the comparative advantages of relevant alleles and traits in fields with contrasting drought scenarios. This will be performed via field experiments and by developing a new generation of crop model able to estimate the effects of alleles on crop growth, yield and water-use efficiency Results and methods will be diffused (i) to breeders via the parti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Functional genomics of g protein-coupled receptors' (1998-2002) under Fifth Framework.

assistant: **Objectives**

Applications are invited for postdoctoral positions in the area of functional genomics of G protein- coupled receptors. By using genetically tractable model organisms, such as yeast and c. elegans, together with mammalian cell target validation systems, human GPCR signaling networks will be studied. GPCRs play a role in inflammatory diseases, thrombotic and cardiovascular disorders, metabolic dysfunction and diseases of the central nervous system. Additional insight into their precise functions will help to define individual GPCRs and associated signaling molecules as targets for drug therapy. The research will be conducted at the Aventis Center for Functional Genornics (ACFG) in the prime biotech environment of Martinsried, Gerrnany. Aventis Pharma is a world leader in the field of drug discovery. The ACFG, one of three Aventis genomics centers, offers 2800 sq. meters of laboratory space devoted to research utilizing a broad range of current genamics technologies. The ACFG offers postdocs the opportunity to learn state-of-the-art technologies in functional genomics and proteomics, but also provides access to Aventis's extensive resources in lead generation (biotechnology, chemistry and HTS) and strategic alliances with academic and biotech partners in Europe and North America. Postdoctoral fellows are encouraged to present their work at scientific meetings and to publish in internationally recognized journals. We are looking to recruit highly motivated scientists who share our interest in using functional genomics and model organisms to identify new drug targets and develop innovative assay systems for target validation and HTS of Aventis' growing compound libraries. The ideal candidate will have experience with molecular biology and biochemistry. Experience with eukar
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Leading in the brave new world: human - robot dynamics' (HURO).

assistant: **Innovation**

Leading diverse human-robot or human-AI teams is slowly becoming the new normal. As automation and AI become integral to many industries, leaders must learn how to manage teams that include humans and AI/robots. Although there is plenty of training on how to use the technology, however, no one is teaching leaders how to lead the technology, thus creating skills gaps and workforce adaptability issues. As organisations face digital disruption, leaders must integrate these digital innovations into their operations and inspire their teams to become ‘technologically savvy’. However, despite the pressing need to better understand how to cultivate cohesive team dynamics amidst human and AI entities, research in this field is limited, which is problematic as leaders lack evidence-based solutions to deal with these novel challenges. Therefore, this project aims to unlock the potential of human-AI collaboration by: 1) uncovering the essential leadership qualities needed to effectively lead human-AI teams; 2) optimizing the design of virtual teams, where humans and AI work symbiotically; 3) pioneering the use of the newest AI for accurately assessing individual traits through natural language analysis; 4) investigating how feedback acceptance varies when it comes from human or AI sources. This research integrates the scientific fields of leadership, organisational psychology and IT, which pushes the boundaries of traditional research domains. Moreover, it is built on the newest technological trends and employs cutting-edge deep neural network technologies offering a state-of-the-art exploration of the subject. All in all, by achieving these objectives, this project will reshape the future of work, empowering organizations to harness the full potential of human/AI teams, enhance le
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Development of biodegradable conducting scaffolds for treating peripheral nerve lesions taking into account the influence of mechanical vibrations on neurons regeneration in tissue engineering'.

assistant: **Innovation**

The proposed project aims to develop engineered biodegradable conducting 3D scaffolds capable of promoting neuronal survival, as well as axon extension and guidance, for treating peripheral nerve lesions. Current approaches focus on the sensitivity of neurons to the surrounding environment, which includes surface topography, biochemical cues, and electrical activity. Constructs implanted in vivo are also subject to mechanical constrains that have an impact on tissue formation. This project aims to investigate the influence of these mechanical stimulations on scaffolds and neuronal cells proliferation. Moreover, the mechanical constrains applied on engineered tissues inside the body will be evaluated with flexible biodegradable strain sensors developed for this purpose. Finally, scaffolds with various geometries designed to absorb the vibrations will be fabricated and evaluated. This project proposes an additional strategy that can be combined to other therapies to improve nerve regeneration.The first part of the project will be performed at Stanford University, USA, in the group of Organic and Carbon Nano Materials for Electronic Devices led by Prof. Z. Bao.Main tasks: literature search, produce the scaffolds, implement a measurement setup allowing mechanical stimulations of scaffolds in liquid, perform an in vitro degradation study on scaffolds, develop mechanical models, develop and characterize a biodegradable strain sensor.The second part of the project will be performed at EPFL, Switzerland, in the Laboratory for Soft Bioelectronic Interfaces led by Prof. S. Lacour.main tasks: Implement a mechanical stimulation setup in liquid based on existing setup in the lab, produce scaffolds, perform an in vitro study on scaffolds with neuronal cells and mechanical stimulation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Deciphering the Oncogenic Lesions and Pathways of B and T Cell Cancers' to be submitted under Seventh Framework.

assistant: **Abstract**

Lymphoid cancers are among the most common human malignancies and characteristically harbour genomic aberrations. Although databases will soon be flooded with genome sequences from thousands of tumours, interpretation and validation of these data is limited by the genetic variability and uncontrolled environmental exposures inherent to human studies. There is therefore a growing need in complementary approaches that would provide understanding of how and which genomic aberrations underlie tumour genesis. It has become apparent that the generation of DNA double strand breaks during the process of antigen receptor diversification, including RAG1/2 protein-generated DNA breaks during V(D)J recombination, are key intermediates in the appearance of lymphoid neoplasm. In this project, we propose to elucidate the molecular mechanisms, the genomic lesions and the oncogenic pathways underlying B and T cell cancers using a combination of mouse models and cutting-edge cytogenetic, genomic and transcriptomic technologies. We aim (i) to define the major genomic lesions and oncogenic pathways underlying the rapid onset of T-cell lymphomas in a unique mouse model that carries exacerbated RAG-induced genomic instability; (ii) to decipher the genomic lesions and pathways underlying B versus T lymphoma tropism; (iii) to investigate the functional interactions between RAG- and DNA damage response / DNA repair-complexes in suppressing genomic instability and lymphomagenesis; and (iv) to identify and validate lesions and genes underlying human B and T cell cancers using a cross-species oncogenomic comparative approach. In doing so, this study will also 1) increase our understanding of the fundamental mechanisms maintaining genome stability during lymphocyte development; 2) greatly improve i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Extension of transuranus code applicability with NB contaning cladding models'.

assistant: **Objectives**

Due to the lack of appropriate, internationally qualified codes, the proposal aims to provide an analytical tool for the simulation of VVER fuel performance under normal and off-normal conditions. The goal is to be achieved through the extension of the TRANSURANUS fuel code with new models for the high temperature oxidation, plastic deformation and failure of the Nb containing claddings. The proposed work-packages cover database development, model refinement, model development, extensive code validation through post-test computations and VVER plant application for hypothetical accidents. The project assists to reduce the conservatism in the safety analyses, support the verification of the fulfilment of the licensing acceptance criteria and opens the door for the simulation of new, Nb containing cladding materials appearing in the western design PWRs as well.