RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Philosophy as Cultural Self-Knowledge: R. G. Collingwood, Peter Winch and the Human Sciences' under Horizon 2020.

assistant: **Concept**

The input of the humanities and social sciences is vital in fostering a viable civil society. Informed public debate concerning the good life needs the kind of reflexive cultural self-understanding that they can offer. In cultural reflection, conceptual analysis, which is the domain of philosophy, has a key role. This vision of philosophy and the human sciences as cultural self-knowledge currently remains a minority view. However, during the twentieth century, it found powerful proponents in two leading philosophers of history and the social sciences: R.G. Collingwood (1889–1943) and Peter Winch (1926–1997). The aim of the planned project is to confront these two thinkers and tease out their underlying visions of philosophy. By engaging with these thinkers, the present project reopens questions about (1) the place of philosophy among the sciences, as well as (2) issues concerning the very nature of philosophical inquiry and (3) its impact on civil society and its challenges. The relation between Collingwood and Winch remains almost completely unexplored at present. The relationship between philosophy and human historicity, which was a key issue for both, presently remains underdeveloped in the analytic tradition. The planned research will take advantage of extensive manuscript material at the Centre for Ethics as Study in Human Value (CE) at the University of Pardubice (UPa). The CE has the unique combination of full access to the relevant Peter Winch manuscripts and a team of scholars knowledgeable in the post-Wittgensteinian tradition to which Winch belonged. The project furthermore includes a short visit to the Collingwood Archives at Oxford. The scholarship will enhance the CE’s reputation as the ‘go-to’ place for anyone doing research in the post-Wittgensteinian tr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Sustainable Hydrogen and Aluminothermic Reduction Process for Manganese, its alloys and Critical Raw Materials Production' (HAlMan) targeting Horizon Europe.

assistant: **Abstract**

Decarbonization of processes, scarcity of raw materials and Europe independence on key resources, valorisation of industrial waste are all key and strong challenges the EU metallurgy industry is facing and will have to deal with in the next decades to remain sustainable while keeping its economic competitiveness. This is particularly true for the manganese (Mn) & Mn ferroalloys industries. HAlMan represents a game changer in the metallurgical industry in view of developing sustainable processes with low carbon footprint, low energy consumption, no solid waste generation, valorisation of secondary raw materials from mining and metallurgical industry. HAlMan will demonstrate at TRL 7 an integrated process to produce Mn metal and Mn alloys from Mn ores and Mn-containing waste by using hydrogen and secondary aluminum (Al) sources as reductants. As metallurgical processes have large share in CO2 emission, decarbonization in metallurgical industry is essential to operate metal production in Europe. The benefits of the HAlMan innovative process will go beyond Mn and Mn Ferroalloys industries, and it presents a unique intersectoral approach in circular economy where:•Al-containing  dross/scrap, and waste from ferromanganese industry are valorised to produce directly new Al-Mn master alloys for Al and Steel industries• metallurgical grade alumina (the feedstock for Al production, produced almost exclusively from Bauxite which is a CRM for EU) is produced via a zero-carbon footprint process •the extraction of critical raw materials, including REEs, from the alumina production process by-products will be demonstrated•the production of manganese oxide and cell fabrication for lithium-ion battery applications will be demonstrated.Additionally, HAlMan project studies heat and hydroge
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'High precision and performance heliostat for variable geometry fields of Thermosolar Plants' (HELITE), addressing dissemination and exploitation.

assistant: **Impact**

TEWER has verified that solar fields implemented today are calculated considering a unique design of heliostat and presenting heliostat is not only characterized by the energy which is able to reflect but by how it is reflected. The configuration of the solar field and the influence of geometrical factors are directly related to the production and it is essential to take into account regarding the design, all weather operation conditions in order to get a high technology performance.Until today, although the market is asking for it, there is no product that allows variable geometry designs of solar field, allowing them to increased the energy efficiency and the overall performance from the field, improving the relation benefit/cost of current systems.TEWER aims to use this need to sell their pioneer solution in the field of engineering for solar power energy by concentration to be able to demonstrate management companies of solar plants that their product offers a much more efficient and cost-effective technology than the one that exists currently.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Ocean Medicines' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Marine organisms have the capacity to produce a variety of biologically potent natural products. Such novel molecules have new mechanisms of action and therefore could be used to treat human diseases and enhance the quality of life, especially in the ageing segment of the population. However, although there is growing interest in marine natural products (MNP) as potential therapeutic agents for human age-related diseases, few MNPs have reached clinical trials and the market.  To fully exploit these promising biological resources, new strategies in the pipeline as well as a new cohort of cross-disciplinary trained scientists are needed to overcome existing bottlenecks and ensure the production of high value biomolecules. Ocean Medicines is a network of academic, research centres and SMEs across Europe, with proven experience in higher education, training and endowed with state-of-the art scientific and technical expertise and infrastructures.Our aim is to establish a network of collaboration and knowledge-exchange between industrial and academic partners to further develop lead compounds from marine microorganisms having anticancer or anti-infective effects that have already been identified by the consortium.  To achieve this a secondment  programme will be set up to prepare a new generation of marine biodiscovery scientists that will be trained on how to isolate compounds from bioactive bacteria/microalgae and take these through to semi-industrial scale-up for further development and toxicity testing at the pre-clinical level. The Ocean Medicines programme also considers commercialization, innovation and entrepreneurship activities including how to start a new business and how to favour an industrial career to seconded researchers. We are confident that the establishmen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Next Generation Molecular Ecology' to be submitted under Seventh Framework.

assistant: **Abstract**

There is an immediate need to increase our understanding of the genetic basis for fitness differences in natural populations (Ellegren and Sheldon Nature 452:169-175, 2008). Fortunately, technological developments within genome research, notably the recent ability to retrieve massive amounts of DNA sequence data based on next generation sequencing , will make possible completely novel investigations of the link between genotypes and phenotypes in non-model organisms. With our background as major players in molecular ecology and evolutionary genomics of non-models for the last 15-20 years, we are excellently placed to take on a leading role in this process, developing a Next Generation Molecular Ecology . This research program will combine studies of candidate genes with large-scale gene expression analysis, several mapping approaches and comparative genomics to study the genetic basis of trait evolution in wild bird populations. First, we will search for and analyse loci involved with reproductive isolation and adaptive population divergence in a well-known system for speciation research the pied flycatcher and the collared flycatcher. A milestone of this program will be genome sequencing of the two flycatcher species. Second, we will track the genetic basis of behaviour using a unique breeding population of zebra finches and benefitting from the recently obtained genome sequence of this species. Third, we will identify the targets for adaptive evolution during avian evolution using comparative genomics. Overall, the program will be able to reveal the molecular genetic architecture behind phenotypic variation. The potential for scientific break-through in this interdisciplinary program should be significant.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The Neural Determinants of Perceptual Decision Making in the Human Brain' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

How do we make reliable decisions given sensory information that is often weak or ambiguous? Current theories center on a brain mechanism whereby sensory evidence is integrated over time into a “decision variable” which triggers the appropriate action upon reaching a criterion. Neural signals fitting this role have been identified in monkey electrophysiology but efforts to study the neural dynamics underpinning human decision making have been hampered by technical challenges associated with non-invasive recording. This proposal builds on a recent paradigm breakthrough made by the applicant that enables parallel tracking of discrete neural signals that can be unambiguously linked to the three key information processing stages necessary for simple perceptual decisions: sensory encoding, decision formation and motor preparation. Chief among these is a freely-evolving decision variable signal which builds at an evidence-dependent rate up to an action-triggering threshold and precisely determines the timing and accuracy of perceptual reports at the single-trial level. This provides an unprecedented neurophysiological window onto the distinct parameters of the human decision process such that the underlying mechanisms of several major behavioral phenomena can finally be investigated. This proposal seeks to develop a systems-level understanding of perceptual decision making in the human brain by tackling three core questions: 1) what are the neural adaptations that allow us to deal with speed pressure and variations in the reliability of the physically presented evidence? 2) What neural mechanism determines our subjective confidence in a decision? and 3) How does aging impact on the distinct neural components underpinning perceptual decision making? Each of the experiments des
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Vienna International Postdoctoral Program' (VIP-2).

assistant: **Innovation**

The VBC International Postdoctoral Program (VIP2) sets new standards in postdoctoral training in the Life Sciences by providing talented young scientists with outstanding support to conduct ambitious research projects in an international, interdisciplinary, and inter-sectoral environment. The program fosters scientific independence, encourages groundbreaking, career-making projects, and enables fellows to establish valuable contacts to academic and non-academic sectors.  The Vienna BioCenter (VBC) has a 30-year history of scientific excellence and training. Four academic institutes (IMP, IMBA, GMI, MFPL) form the basis of this application. They are devoted to basic research in all areas of Life Science. Research topics range from structural biology to organismal biology, from gene expression to neurobiology, from microbiology to molecular medicine which encompass the full range of model systems from microbes, stem cells, plants, invertebrates to vertebrates. Together with 21 biotech companies, the VBC is Austria’s largest life sciences research center and a stellar example of an interdisciplinary and inter-sectoral campus.  VIP2 is a 3-year postdoctoral fellowship program open to candidates with backgrounds in biology, chemistry, physics, medicine, engineering and computer science. The selection is a bottom-up procedure where fellows select two mentors and conceive a research project that forms the basis for the selection. VIP2 fosters scientific independence by selecting projects that have the potential to develop into distinct research lines and by providing candidates access to outstanding scientific core facilities. VIP2 fellows are mentored through a structured program that trains fellows for skills required to attain high-level positions in different scientific se
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Validation of a Lung Cancer Plasma Reflex Test Using Epigenetic Biomarker for Cancer Detection' under Horizon 2020.

assistant: **Concept**

The objective of “proLungPlasma” is the clinical validation of a lung cancer test, which detects DNA methylation of the specific biomarker mSHOX2. Methylation of DNA is an important epigenetic process involved in fundamental biological processes as development and cell differentiation. Aberrant DNA methylation plays a major role in cancer development. Epigenomics  is very successfully engaged in epigenetic research since 1998 resulting in an outstanding proprietary platform for epigenetic biomarker discovery for cancer. Epigenomics is now market leader in epigenetic biomarker test kits detecting most frequently occurring forms of cancer as colorectal and lung cancer from different sample materials. Lung Cancer is the most deadly of all cancer diseases. Unfortunately, lung cancer screening by Low Dose Computer Tomography (LDCT) is burdened by unacceptably high false positive rates. The newly developed Epi proLung Plasma Reflex Assay is urgently required as a tool for reducing false positive rates. Therefore, the Epi proLung Plasma Reflex Assay is a highly anticipated pre-requisite for successful implementation of lung cancer screening in Europe. This business innovation project will validate the Epi proLung Plasma Reflex Assay for the diagnosis of lung cancer in plasma under the upcoming new IVD regulation. The validation process to be performed in this business innovation project will be used as a blueprint for the standardized validation of all further epigenetic biomarker blood tests. Epigenomics’ established test platform, its product development and regulatory expertise, and the standardized validation process are expected to kick-off further strong growth on major global MDx markets.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Third Wave HCI: Methods, Domains and Concepts'.

assistant: **Innovation**

This proposal is for interdisciplinary research that will help bring to maturity the emerging paradigm of  third-wave HCI , which addresses interaction as situated meaning-making in everyday life. With my established interdisciplinary research team, I will design prototypes that show how third-wave thinking is relevant for domains of recognised importance to help bring this paradigm to the centre of HCI. We will develop an integrated set of tactics and orienting concepts based on our practice to elucidate and support research and design in third-wave HCI. Crucially, we will develop a new methodology for this research, based on the deployment and study of 50   100 batch-produced prototypes in real-world situations. This will mark a significant leap forward, allowing prototype technologies to be studied using social scientific and design-led methods in field trials several orders of magnitude larger than normal   a development from which third-wave HCI, with its commitment to multiple, local appropriations, will benefit enormously.  The project will be centred around two Case Studies in which we will develop robust and highly finished prototypes, batch produce them in large numbers, deploy them in large-scale field studies with members of the general public as well as specialist commentators, and use a variety of traditional and experimental methods to capture their experiences.  The first Case Study will produce a suite of electromechanically extended sensors that provide resources for environmental awareness in the home without being judgmental or didactic. The second Case Study will develop mobile devices that display readymade, location-based information to provide a  behind the scenes  view of local neighbourhoods.  When dozens of these prototypes are in use simultan
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'WESTinnoMAR' (WESTinnoMAR) under Horizon 2020.

assistant: **Objectives**

The proposed project addresses the action for “Establishing services “Enhancing the innovation management capacity of SMEs” in the Enterprise Europe Network” to improve the innovation management capacity of SMEs. The activities foreseen under this proposal is to give Activity 4 of EEN services to SMEs. 10 full enhancing SMEs’ innovation management capacity service packages will be offered to SME’s till the end of 2018 and every service package is foreseen as 7 days in the proposal. Additionally, 14 day KAM serviceswill be offered for successful beneficiaries of SME instrument Phase 1.


**Keywords:** innovation, SME, research&development
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Functional dissection of metabolic checkpoints in lymph node fibroblastic reticular cells' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Induction and regulation of optimal immune responses depends on the proper functioning of fibroblastic reticular cells (FRCs) of secondary lymphoid organs (SLOs). Energy balance maintained through the choice of ideal metabolic pathways critically influences the performance of immune cells. Currently, the bioenergetic demands of FRCs and how they impinge on their function remain elusive. The overarching goal of this project is to decipher the bioenergetic needs of FRCs in homeostasis and during inflammation and to uncover the critical immunological signals involved in the metabolic shift of FRCs that underpin immune activation. Combination of state-of-the-art models for in vivo FRC targeting, novel methods from quantitative systems biology and molecular perturbation analysis will be utilized to reveal the metabolic landscape supporting optimal FRC function and the induction of immune responses. Specifically, “FRC BioEnergetics” will determine: The bioenergetic profile of homeostatic vs. inflammatory FRCs and identify the metabolic switching necessary to support the transition to immune-activated state of FRCs (Aim 1); Identify the immunological signals that trigger metabolic switching necessary to support FRC activation (Aim 2) and Determine to what extent metabolic regulation of FRC function impacts on global immune responsiveness (Aim 3). The focus of the multidisciplinary research program on metabolic regulation of FRC function as central means for the control of immune responsiveness will reveal novel principles underlying immune homeostasis and immunity. “FRC BioEnergetics” will expand our knowledge of the intricate metabolic regulation of immune cell function, with the final goal to provide novel options to modulate immune responses by targeting FRC metabolism and