RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Bottom-Up generation of atomicalLy precise syntheTIc 2D MATerials for high performance in energy and Electronic applications – A multi-site innovative training action' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The “graphene rush” has triggered a great interest in the design and fabrication of synthetic 2D materials (S2DMs) excelling in their chemical and physical properties for future emerging technologies addressing numerous societal needs, such as faster and better performing electronics, as well as energy storage and conversion. To match the societal benefits of being at the forefront of new technological and scientific developments, the EC requires a highly skilled scientific and technical workforce that can efficiently finalize the shift to a true knowledge-based society. ULTIMATE will provide to 15 talented young researchers a well-structured training in the burgeoning field of S2DMs by developing their knowledge and understanding on: i) how to generate novel atomically precise 2D materials with defined structure and composition, and ii) how to best exploit their unique and tunable properties for electronics and energy applications. This training-through-research requires an intersectoral approach by specialized and skilled scientists from different (sub-)disciplines including molecular modeling (TUD), organic, macro-/supramolecular synthesis (TUD, HUB, UAM), production of S2DMs (GRA, TUD, UNISTRA, IIT), hierarchical self-assembly (UNISTRA, KUL, HUB, CNR), surface and interface studies (KUL, EMPA, IBM, KFUG, CNR, APE, IIT, UNISTRA), photochemistry and photophysics (UNIME, HUB, UNISTRA, IIT), device fabrication and characterization (IIT, TUD, UNISTRA), and other skills, as well as a strong commitment to the training of young talents with the ultimate goal of achieving scientific breakthroughs in this very topical area of science and technology. The ULTIMATE network will strengthen the EC training efforts by delivering 540 person-months of unprecedented cross-disciplinary
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Negative Regulation of Inflammatory Responses Revealed with Camelid Nanobodies'.

assistant: **Concept**

The innate immune system evokes inflammation to control pathogens or damage. Sophisticated mechanisms interpret molecular triggers to activate inflammasomes or transcription of pro-inflammatory genes. While numerous autoinflammatory conditions underline the need to control inflammation, we still rely on simplistic models to understand its negative regulation. I hypothesize that an intricate signaling network interprets information to prevent or downregulate inflammation. Understanding these so far elusive processes demands radically new cell biology tools, which I will develop and apply in ‘DEFLAMMATION’. I propose to define signaling hubs that integrate cellular input and coordinate effectors to actively downregulate inflammation where beneficial to the organism. To yield unprecedented molecular insights, we will apply nanobodies to inhibit protein function, manipulate post-translation modifications, and visualize endogenous proteins and their binary interactions. I hypothesize that two poorly understood members of the NLR family, NLRC3 and NLRX1, act as signaling hubs that coordinate negative regulation of pro-inflammatory gene expression. No such coordinator is known for inflammasomes. In objective 1, we will pinpoint how NLRC3 controls inflammation and T cell activity. I hypothesize that NLRC3 forms anti-inflammatory signalosomes to control the ubiquitination status of pro-inflammatory signaling components. In objective 2, we will reveal how NLRX1 counteracts interferon responses, inflammation, and proliferation. We will explore whether NLRX1 activation coordinates organelle-specific autophagy to remove pro-inflammatory signaling complexes. In objective 3, we will identify novel regulatory circuits that control inflammasome activation using CRISPR/Cas9 and cDNA scre
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Development of a non-invasive hypoglycaemia sensor for diabetes patients'.

assistant: **Objectives**

Blood glucose monitoring is important in the care of diabetes mellitus and is presently accomplished via a “finger-stick” in which a lancet is used to prick the finger and withdraw a small amount of blood for testing. The problem with the existing “finger-stick”-devices is that blood sampling is painful, it increases the risk for infections and the test is discontinuous.  A method for measuring the status of a diabetes patient continuously is preferred, especially at night when the risk of undetected hypoglycaemia is present. Systems for continuous (non-invasive) blood glucose monitoring show promising results for measuring high blood glucose values (hyperglycaemia). However, these systems are not reliable when it comes to measuring low blood glucose values (hypoglycaemia). This is due to the fact that a small variation in the blood glucose concentration in the “hypo-region” has a great impact on the status of the patient. In this project volatile components emanated from the skin are used to determine the state of diabetes patient; one of these components is acetone. An apparatus to clinically test the relation between the amount of acetone and the state of hypoglycaemia (and the concentration of blood glucose) has to be developed. Clinical tests (clamp tests) will be performed in an (academic)hospital. Furthermore, research has to be performed into the combination of several techniques (e.g. impedance spectroscopy) with skin gas measurements to obtain an overall picture of the status of a diabetes patient. Measurements of acetone permeation through the skin and the use of membranes to protect the sensor and/or to enhance the signal are needed.   Sensors need to be developed to miniaturise the system. The ultimate goal is to develop a sensing system capable of measurin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'High Accuracy Service Harnessed Trusted Application and Governance', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The growing introduction of automated or even autonomous machinery on farms makes the need for good quality data more critical. Moreover, the demand is increasing to log the outputs of those machines for analysis, documentation and compliance. However, current datafiles sent to, or retrieved from machinery lack quality standards. They cannot be certified because any guarantee on the integrity of the used data and workflow is missing. HASHTAG is therefore leveraging space assets and services to safeguard the reliability of data ensuring trusted application and governance. Within a period of two years, three building blocks will be developed to proof our concept: 1. Standardising protocols, logging and verifying prescribed tasks using machine data flows to assure as-applied maps are trustworthy.2. Standardising the processing of high quality EO data from Copernicus into prescription maps.3. Using Galileo’s High Accuracy Service and Navigation Message Authenticator in a GNSS receiver to provide trusted and accurate machine positioning. Integrating these components will result in a workflow capable of generating a transparant and authenticated data chain of EO data to as-applied maps. This is relevant for current reality, where food production and processing are international businesses with ingredients from around the world, governed by food standards and environmental regulations. Our solution, deploying space assets, can be used anywhere in the world, hence leveraging European knowledge and expertise to enable the next level of sustainable and regenerative farming. International partners from Serbia are included and use cases in Brazil, Ukraine and Indonesia will be explored. HASHTAG will reach out to standardisation initiatives in agritech to promote its results and inc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'E-enabled Cabin and Associated Logistics for Improved Passenger Services and Operational Efficiency' (E-CAB) targeting Sixth Framework.

assistant: **Abstract**

The volume of passengers and complexity of airports have diminished air travel quality to the point where it affects passengers universally, irrespective of travel class. The declining ?end-to-end? travel quality is increasingly caused by the negative emotions generated in gaining access to the aircraft and the significant difference between home life and life on-board. E-Cab solves these problems by giving greater control to passengers by collecting, manipulating and providing information. This allows passengers to know when they are expected on the aircraft, to know the location of their luggage and to determine if they have time to carry out leisure activities in the airport (eating, shopping etc) or to maximise productive time for business purposes. On-board the aircraft, passengers shall have control over the means by which they access their connectivity, with options ranging from mobile phones, PDAs, laptop computers to the classical IFE interface. The passengers shall also be given the means to control their use of time on-board the aircraft by being able to, for example, order meals at times that suit their individual needs. Offering this control is not possible with the current infrastructure so there is a considerable research task in developing the best means of improving the efficiency and effectiveness of the airlines processes so that they are able to offer passengers this control in an economically feasible manner. To correctly manage the complexity of the development task, these technical aspects are divided into four main streams covering respectively: Passenger Services, People Moving, Freight Handling and Catering Services. The successful completion of this project shall provide the airports and airlines with an environment that enables the possibilit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Regulation of selective translation via signal transduction pathways'.

assistant: **Concept**

The overall rate of protein synthesis is an important factor modulating cell and tissue metabolism. In addition, the translational machinery plays key roles in controlling gene-specific expression in eukaryotic cells. The regulatory mechanisms involve changes in the activities of components of translational complexes that lead to selective translation of specific subsets of messenger RNAs. Modulations of translational activity are primarily mediated by changes in the phosphorylation states of translation factors or RNA-binding proteins promoting specific modes of translation. Kinases closely associated with translation initiation complexes have a huge potential to regulate selective modes of translation. However, despite many studies on signalling pathways controlling the phosphorylation status of the translation machinery, little is known about how these modifications regulate the quality of the translation. The main research objective is to uncover novel molecular mechanisms regulating the expression of specific genes at the translation level triggered by signalling pathways. The project proposed will make use of a variety of modern molecular biology, biochemistry and cell biology techniques, including detailed proteomic and genomic analyses. In addition, the clinical relevance of the new identified mechanism will be analysed in human brain cancer. Understanding the mechanisms selecting specific mRNAs for translation would not only explain the principles underlying rapid signalling responses controlling translation and the phenotypical consequences but would also allow development of molecular strategies for therapeutic interference in human diseases with deregulated signalling pathways.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Design and Characterization of a Compton Camera Using 3D-CZT Detector Modules with Advanced Signal Processing and Polarimetry for MeV Astrophysics'.

assistant: **Innovation**

The energy range between 0.1 MeV and 10 MeV is called as “MeV gap” in astronomy, primarily due to the low sensitivity of the instruments in this energy range. Compton imaging is the key technique proposed to overcome this challenge. The goal of this project is to design a cost-efficient Compton Imager. CZT detectors have the potential to be game changers when used in a Compton Imager, since they offer good energy resolution at room temperatures. Hence in this project, we plan to design, simulate and calibrate a Compton Camera based on the 3D-CZT Drift Strip Detectors, developed previously at DTU Space, Technical University of Denmark. An additional advantage is that the Compton Imager could be used as a hard X-ray polarimeter, as azhimuthal angle of the Compton scattering depends on the polarization of the incoming photon. Recent observations from the Imaging X-ray Polarimetry Explorer (IXPE) have attracted massive interest from the high-energy astrophysical community towards X-ray polarimetry. However, IXPE operates in the soft X-ray band of 2-8 keV, where the thermal processes interlap with non-thermal processes. Hence, a polarimeter in the MeV band where the non-thermal radiative process dominates is of large interest. We plan to design a laboratory model of the Compton telescope using a stacked configuration of 3D CZT detectors and evaluate its imaging and polarimetry performance through simulations followed by experimental validation. The recent development of this detector includes using Artificial Neural Networks for sensor Signal Processing and Real-time measurement of radiation interactions which would also be ideal for this project. The immense expertise of the host supervisor and group in semiconductor detectors would complement the candidate's experience in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Biodiversity and connectivity in the resilience of coastal marine communities' under Seventh Framework.

assistant: **Concept**

Changes in diversity underpin the very nature and integrity of ecosystems, including how they function, deliver goods and services, and respond to disturbances. Yet understanding the underlying mechanisms of biodiversity change remains both one of the greatest challenges in ecological science and of fundamental importance to resource management and conservation. The key problem is the need to integrate the effects of different factors operating on different space and time scale on biodiversity. Biodiversity assessment and the maintenance of environmental quality are central to the management of coastal ecosystems, multi use and multi value systems. This research will focus on the study of meta communities, alpha and beta diversity as a way forward for ecology over regional spatial scales and relevance to resource management. The research will investigate the resilience of hard bottom marine benthic communities in relation to habitat complexity and degrees of connectivity. Appropriate experiments will be set up in order to evaluate the recovery of benthic communities after disturbance according to the different degree of connectivity between assemblages and taking into account the life history of the different benthic species. particular attention will be given to Marine Protected Areas and their role in preserving biodiversity
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'HyQuality Europe', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

HyQuality Europe aims to understand hydrogen fuel quality across Europe and enable HRS operators to provide assurance that their fuel is fulfilling the required quality standards. The project is designed to understand hydrogen fuel quality in Europe by carrying out a representative mass market investigation of European HRS hydrogen quality, collecting 300 spot samples of both light-duty (700 bar, <60 g/s flow rate) and heavy-duty samples (350 bar, >60 g/s flow rate) from at least 100 HRS in at least 13 European countries. These samples will be analysed by the leading hydrogen analysis laboratories in Europe, and the results will be published in an open-source database. The results will provide the data to clarify the Occurrence Class of different European HRS impurities, from which HRS operators will be able to form a cost-effective risk assessment quality assurance plan instead of taking an expensive prescriptive approach. By facilitating HRS operators to provide low cost quality assurance the project will lower the price of hydrogen at the nozzle and subsequently increase consumer confidence, increase the incentive for fleet operators to switch to hydrogen vehicles, and enable the widespread deployment of hydrogen vehicles and refuelling infrastructure. The project will also advance upon state-of-the-art hydrogen quality assurance by instrumenting 3 HRS with online analysers, and develop testing capacity by laboratory proficiency testing 10 European hydrogen analysis laboratories in line with ISO standards. Finally, the occurrence of a minimum of 4 new impurities will be investigated using wide scope analytical techniques. The project will proactively seek to influence the development of ISO standards and future research on this crucial topic through the involvement o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Diamond materials for the photocatalytic conversion of CO2 to fine chemicals and fuels using visible light' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

In DIACAT we propose the development of a completely new technology for the direct photocatalytic conversion of CO2 into fine chemicals and fuels using visible light. The approach utilises the unique property of man-made diamond, now widely available at low economic cost, to generate solvated electrons upon light irradiation in solutions (e.g. in water and ionic liquids). The project will achieve the following major objectives on the way to the efficient production of chemicals from CO2 :- experimental and theoretical understanding of the principles of production of solvated electrons stemming from diamond- identification of optimal forms of nanostructured diamond (wires, foams pores) and surface modifications to achieve high photoelectron yield and long term performance- investigation of optimized energy up-conversion using optical nearfield excitation as a means for the direct use of sunlight for the excitation of electrons-characterisation of the chemical reactions which are driven by the solvated electrons in “green” solvents like water or ionic liquids and reaction conditions to maximise product yields.- demonstration of the feasibility of the direct reduction of CO2 in a laboratory environment.The ultimate outcome of the project will be the development of a novel technology for the direct transformation of CO2 into organic chemicals using illumination with visible light. On a larger perspective, this technology will make an important contribution to a future sustainable chemical production as man-made diamond is a low cost industrial material identified to be environmentally friendly. Our approach lays the foundation for the removal and transformation of carbon dioxide and at the same time a chemical route to store and transport energy from renewable sources. This