RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Micro-nano integrated platform for transverse ambient intelligence applications' (MINAMI).

assistant: **Concept**

MINAmI addresses AmI applications where personal mobile devices act as a gateway to AmI. MINAmI vision makes the user progressively be in control of his AmI environment, then interact with everyday objects to monitor and control environmental or health parameters.MINAmI develops tools, methodologies and an open platform and implement these technologies into real devices/systems in demonstrators. Ethics and privacy issues linked to AmI will be strongly assessed as well as user acceptance of the solutions. MINAmI multidisciplinary and participatory design approach will reduce the time to adopt AmI disruptive concept, facilitating a constant dialogue between technology and application developers, end users and application field experts.The open platform previously developed in MIMOSA will be enriched in MINAmI as new technologies offer more functionalities for wider applications. Micro-Nano smart devices with enhanced short range connectivity will be developed and validated through field trials in wide and transverse applications, from consumer to niche markets.The main technical focus in MINAmI is in the development of:- mass storage RF tags based on low power innovative technologies- active event sensitive tag technology including new low-cost time reference- low-cost/low-power sensors and actuators including nanosensors, 9D integrated Inertial Measurement Unit and 3D distributed vision systemsIn MINAmI, a global platform taking into account the constraints of integration, industrialisation and compatibility with advanced CMOS platforms will integrate these technologies. MINAmI links demonstration, validation and exploitation. Service providers and companies will develop and support the applications in pre-competitive products that include:- drugs monitoring and conditio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Catalytic and mechanistic studies of Organometallic reactions in water: focus on alkylation processes' (AQUAMEC).

assistant: **Concept**

Recently, concerns over hazardous waste generated during catalytic reactions and separation of products from catalyst increasingly led to the development of systems that employ water as solvent. An understanding of the specific mechanisms in water is required, however, for a rational optimization of processes. Pd-catalyzed allylation has played a major role in the evolution of synthetic catalysts for asymmetric C-C bond-forming reactions in organic solvent. However, whilst ligands are exceptionally selective, its mode of asymmetric induction has remained very much a 'black-box'. We propose to exploit the key interactions and how water could change the critical step of the reaction in classical organic solvents. Through the systematic study of structure-selectivity relationships, single crystal X-ray analysis, NMR spectroscopy of intermediates and Kinetic studies, the Fellow will study the asymmetric allylic alkylation reactions in aqueous medium, acquiring new competencies in the areas of physical organic chemistry, mechanistic aspects of catalysis, isotopic labelling, high field multinuclear (dynamic) NMR, and reaction kinetics. We will study as the enantioselectivity of asymmetric carbonylations could be controlled. Moreover, we want to understand the different behaviour of Pt catalyst in allylation reaction. Undertaking the project at the Community level will be very beneficial in three senses. Firstly, research and publications in mechanistic and synthetic aspects of asymmetric catalysis will strongly raise the profile of an area in which Europe lags substantially behind, as compared to the USA and Japan; secondly it will ensure that the Fellow's skills in aqueous chemistry will be retained in Europe and will be transferred to the host group. Finally, an excellent p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'COSMOlogy employing MAchine Learning Techniques and Advanced statistics' to be submitted under Horizon Europe.

assistant: **Abstract**

Some of the biggest open problems in modern cosmology are the nature of the cosmic dark sector, the discrepancy between the theoretically predicted versus the observed value of the cosmological constant, and the growing cosmological discordances and tensions between different observational probes. Notably, the Hubble constant, which describes how fast the Universe is expanding when measured locally, has an enormous statistical disagreement with that inferred from the early Cosmic Microwave Background data. These inconsistencies, in turn, necessitate the formulation of new physics beyond the standard cosmological model. Current and ongoing observations, together with upcoming surveys, will produce large volumes of data, whose accumulation and processing will require an upgradation and increase in the sophistication of our statistical tools before applying them to specific problems. Thus, we propose to build a deep learning architecture using advanced statistics in machine learning algorithms like neural networks to be integrated into cosmological community codes for emulated parameter inference. This will help us to select, in a model-independent way, generic features of some cosmological theories that satisfy all observations. Utilising the power of deep learning will be an ideal space to investigate new physics in the observational sector and discriminate between models that are degenerate in terms of current observational approaches, fostering the development of data-driven science as a valuable companion to the model-driven paradigm. The fellowship will contribute to the researcher's career development by acquiring advanced skills in machine learning approaches using Bayesian statistics and developing skills within the cosmological community through a series of event
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Enforced ATP wasting as a general design principle to rationally engineer microbial cell factories' (StrainBooster).

assistant: **Innovation**

One global challenge of humanity in the 21st century is the shift from a petrochemical to a bio-based production of chemicals and fuels. An enabling technology towards this goal is metabolic engineering which uses computational and experimental methods to construct microbial cell factories with desired properties. While it has been shown that genetically engineered microorganisms can, in principle, produce a broad range of chemicals, novel approaches to improve the performance of those strains are urgently needed to develop economically viable bioprocesses.To this end, we propose a new metabolic design principle to rationally engineer cell factories with high performance. Supported by a recent pilot study, we postulate that suitable genetic interventions combined with mechanisms that burn (waste) an extra amount of ATP (e.g., by artificial futile cycles) will increase product yield and productivity of many microbial production strains. Key objectives of StrainBooster are therefore: (1) to use computational techniques and metabolic models to identify gene knockout strategies whose coupling with ATP wasting mechanisms can boost the performance of microbial strains and to prove in silico that those strategies exist for many combinations of substrates, products, and host organisms; (2) to develop genetic modules that can robustly increase ATP dissipation in the cell; and (3) to experimentally demonstrate the power of the proposed strategy for selected production processes with Escherichia coli. To reach these ambitious goals, an interdisciplinary approach will be pursued combining theoretical and experimental studies and making use of innovative methods from systems and synthetic biology.If successful, StrainBooster will not only establish a new and ground-breaking strategy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Sensory Experiences for Interactive Technologies' (SenseX) targeting Horizon 2020.

assistant: **Abstract**

The senses we call upon to interact with technology are still very limited relying mostly on visual and auditory senses. The grand challenge and vision of this project is to gain a rich and integrated understanding on touch, taste, and smell experiences for interactive technologies.We aim to achieve this ambitious grand vision by 1) creating a ‘sensory interaction framework’ on the bases of a systematic empirical investigation of touch, taste, and smell experiences, 2) integrating the generated understanding on the three senses into meaningful and efficient experiential cross-sensory gamuts and interaction principles, and 3) demonstrating the added value of the created experiential understanding on touch, taste, and smell – aka the experiential gamuts – through their integration into the development of multi-sensory systems verifying the short-, mid- and long-term societal and scientific impact (short-term: multi-sensory media experiences; mid-term: interaction concepts for partially sensory impaired people; long-term: multi-sensory interaction approach for life beyond Earth).This research will pioneer novel interaction concepts for interactive technologies in relation to essential components of multi-sensory experiences. This project will transform existing interaction paradigm in Human-Computer Interaction (HCI) and likewise impact other disciplines such as sensory and cognitive sciences by delivering ground-breaking new insights on the experiential dimensions underlying neurological processes and human perception.The PI’s research excellence and her track record (three recent seminal papers on touch, taste, and smell at the premier HCI – CHI conference) provide a rock solid foundation for the feasibility of the proposed scientific venture. This ERC project would enab
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Modernizing Empires: Enlightenment, Nationalist Vanguards and Non-Western Literary Modernities' (NONWESTLIT) targeting Horizon 2020.

assistant: **Abstract**

This project is a comparative study of cultural reforms, linguistic renewal and literary renaissance movements in three imperial traditions, caught between the East-West divide: Russia, Turkey and Japan. It looks at the negotiated cultural models in modernization and westernization processes and argues that their shared historical experience resulted in a common intellectual vocabulary and narrative models shared by otherwise extremely diverse cultures. Despite these unmistakable parallels, literary studies have failed to address this shared history. This project aims to bridge this gap by developing a comparative model, drawing a polycentric and plural map of literary modernity. In three subprojects, this project investigates structural similarities in 1.Questions and concepts in literary criticism; 2.Translational practices and translated works from Europe, and 3.Narrative logic and typologies in fiction. It is the first comparative multilingual study of the non-Western literary modernities to bring these specific traditions together. It contests Eurocentric models of literary history which interprets these cases as failures or late emulations. It challenges an overemphasis on single national traditions or on postcolonial approaches, and limited body of studied texts and analysis techniques in the study of the non-West. The project follows a multi-method research strategy to conduct historical and literary comparisons between the emerging national literary systems, combining qualitative and quantitative methods in order to map transnational networks of narrative strategies, conceptual systems and translation practices. It brings new directions in Digital Humanities, expanding it to non-Western and multilingual comparative research. Finally, it makes a much-needed cont
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Uncovering the genetic roots of ASD and ADHD' (GRASAD).

assistant: **Concept**

Autism Spectrum Disorders (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD) are common neurodevelopmental and childhood-onset chronic disorders. Although ASD and ADHD do have distinct diagnostic definitions, evidence has accumulated to suggest substantial overlap between their symptoms. Despite of being notably impairing and presenting deleterious effects on reproductive success they both are highly prevalent. The goal of GRASAD is the study of two important remaining unsolved issues regarding the genetic underpinnings of ASD and ADHD taking advantage of the most innovative approaches in the neurogenetics field. On one side, GRASAD-I will apply state-of-the-art methodologies to address the question of which and how a diverse set of genetic risk factors are involved in both ASD and ADHD and subsequently to specific symptoms shared between both disorders. On the other side, GRASAD-II will study evolutionary aspects of the genetic roots of ASD from a genomics perspective to shed light on the so-called paradox of psychiatric disorders: given that these disorders are considered maladaptive and have heritable risk, why do they still exist? This study is relevant due to it will not only pave the way for a more precise scientific understanding of ASD and its overlap with ADHD but also can have an impact on psychiatric practice within a precision medicine framework. The evolutionary perspective of the project can generate new hypotheses and guide research, inform treatment strategies, provide a more natural view of disease and elucidate the aetiology of mental illness and suffering. The multidisciplinary nature of the project is strong, involving a combination of well-developed novel approaches in the field of psychiatric genetics. This proposal includes both the transfe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Collaboration for Prevention and Treatment of MDR Bacterial Infections'.

assistant: **Innovation**

The loss of antibiotic effectiveness due to increasing antimicrobial resistance (AMR) is a serious threat to global public health. The IMI2 AMR Accelerator will develop new agents to treat and prevent infections caused by MDR and XDR bacteria, including Mycobacterium tuberculosis and non-tuberculous mycobacteria. The COMBINE proposal addresses Pillar A, the Capability Building Network (CBN) of the AMR Accelerator programme. The COMBINE consortium will form a Coordination and Support Office (CSO) that will support the delivery of projects across the AMR Accelerator, as well as with efficient communication among projects of the Accelerator and within the AMR community. In addition, we will establish an IT infrastructure that will allow for the FAIRification, collection, aggregation, storage, sharing, and analysis of vaccine and antibacterial preclinical and clinical data sets. When setting up the CSO, we will build on learnings from the two IMI ND4BB projects: ENABLE (an antibacterial discovery and development engine) and TRANSLOCATION (which has built an information centre for data sharing). COMBINE partners will work to accelerate scientific discoveries in the AMR field by optimisation and standardisation of animal infection models, and development of improved models for translation of preclinical animal efficacy data and statistical analysis of clinical data. This will set new standards for the translational and predictive relevance of preclinical data and facilitate optimized design for new clinical trials. Results will feed into study and trial design throughout the AMR Accelerator to achieve more stringent and reliable development programmes.


**Keywords:** Antibacterials,  Drug discovery and development,  Clinical trial design and analysis,  Animal infection model
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'An innovative ultra-fine bubble engineered nozzle for sustainable cost-effective water aeration' in the context of a Horizon 2020 call.

assistant: **Objectives**

One of the key processes for improving water quality is aeration. When waste water is cleansed in sewage farms, water aeration is required to enable the bacteria which consume the particles in suspension to thrive. Current aeration technology is slow, inefficient, very power consuming and smell generating. Electricity is a critical input for delivering municipal wastewater services, and today about 1% of the EU electricity demand is consumed by wastewater treatment plants. Electricity costs are usually between 5% to 30% of total operating costs among wastewater utilities worldwide. Nanogentech offers UFine, a time effective technology, consuming organic waste up to 9 times faster than traditional aeration methods and allowing cost reduction of over 80%. UFine also achieves a remarkable oxygen transfer rate of beyond 90%. UFine will target industrial wastewater treatment plants which treat only 60% of industrial wastewater before discharge. In the UK, there are many Wastewater Treatment Utilities that serve populations of over 2,000 people, above which the Directive’s secondary treatment standards applies.During the feasibility assessment, a minimum viable product will be defined, a go-to-market strategy and a supply chain will be established, as well as further development plan will be drafted. Within the overall project Nanogentech aims to optimize the ultra-fine bubble nozzle to enable a perfect scale-up of the solution from small wastewater utilities to greater agglomeration’s discharges and complete a successful demonstration with a wastewater company in the UK.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Intercultural Democracies:  insights from mining conflicts for environmental justice in plurinational Bolivia and Ecuador.'.

assistant: **Concept**

Claims from hitherto excluded indigenous groups have led to the rewriting of constitutions in Bolivia and Ecuador to recognize intercultural democracy. At the same time, indigenous environmental justice movements have increased their contestation of hydrocarbon extraction – and recently mining – due to their socio-political and ecological impacts. Analysis of these movements to date has focused on the consequences of conflicts, but less so on their socio-political and ecological drivers. While evidence has demonstrated the role of an increasing social metabolism as a driver of extraction, less attention has been paid to power relations and competing socio-political forces. These deeply influence the possibilities for a democratic control of the extractive sector, a crucial factor for achieving environmental justice and sustainability.This research aims to unpack the power relations that lie beneath the biophysical flows of expanding resource extraction in the intercultural democracies of the Andes. Two mining-related conflicts in Cuenca Poopó (Bolivia) and Intag (Ecuador), where indigenous organizations claim greater environmental justice specifically through self-determination as part of intercultural democracy, will be analyzed applying mixed methodologies: quantitative analysis of biophysical flows and qualitative analysis of interviews and data. This research will potentially show how ecological and metabolic drivers limit indigenous groups’ democratic participation through multi-scale power relations around resource appropriation, thereby improving the understanding of the political dimensions of these conflicts and informing more sustainable policies for extractive sectors. Training at the host institution (ICTA) will facilitate this research by complementing the