RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Advanced sensor-based design and development of wearable prosthetic socket for amputees' (SocketSense).

assistant: **Innovation**

Limb amputations cause serious physical disabilities that compromise the quality of life of many people around the globe. There are 40 million amputees in the world with an estimated 2.4 million in the EU and approximately 215,000 amputation surgeries performed each year (around 90% are lower limb amputees). Thus, there is a growing demand for efficient prosthetic socket systems due to growing number of amputees and lack of an existing solution for the comfortable socket. This project aims to develop a new solution for a prosthetic socket by developing wearable sensors to be embedded in a socket for the amputee patients to wear in everyday life. The sensors will allow real-time data collection allowing prosthetist to monitor the evolution of the performance of existing socket as well as the anatomical changes of the residual limb of amputees. New algorithms will be developed to evaluate all the biomechanical characteristics so that once the existing socket does not serve the patient, a new socket will be produced automatically without the need for the patient to go to a clinic in advance. SocketSense will meet this healthcare need by means of sensors, biomechanical modeling, AI, unified software and additive manufacturing technologies. The sensors will be developed based on QTSS materials (patent protected under WO2017103592A1). Biomechanical analytical models will be developed to turn the sensor data into optimized socket design. The whole SocketSense technique and procedure will be validated through clinical trials. The proposed solution will help address the societal challenge of personalized health and care solution for the population of lower-limb amputees. The project will implement flexible and wearable electronics into new QTSS material fabricating lightweight,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Identification of protective immune responses to pathogenic mycobacteria' (1994-1998) under Fourth Framework.

assistant: **Objectives**

To evaluate the role of T cell-associated lytic mechanisms in the killing of intracellular mycobacteria, and the contribution of these effector pathways to immunity against tuberculosis and leprosy.Expected OutcomeThe study will obtain scientific data allowing the relative importance of these immune responses in protection against mycobacterial disease, and the heterogeneity of the P2Z (P2X7) receptor in susceptibility to mycobacterial disease, to be evaluated.The function of various T cell subsets in immunity to tuberculosis will be assessed in patients with tuberculosis, without or with co-infection with HIV, and in normal BCG-vaccinated healthy controls. Further studies will assess expression of the P2Z (P2X7) receptor in patients with tuberculosis or leprosy, and in healthy controls. Specific areas of investigation are as follows:* To evaluate whether antigen-specific CD4+ and CD8+ T-cell mediated cytotoxicity reduces the survival of intracellular maycobacteria within macrophages, and the relative contribution of various cytolytic effector mechanisms to this T cell-induced macrophage death (LSHTM, London , University of Oxford, and MRC Laboratories, The Gambia)* To assess the role of the gd T cell subset in cytolysis and cytokine secretion in tuberculosis with/without HIV co-infection (CMDT, Lisbon)* To investigate the mechanism(s) by which extracellular ATP-induced macrophage death (occurring via the P2Z-receptor mediated pathway) reduces survival of intracellular M. bovis BCG, and to extend these studies to other pathogenic mycobacteria (University of Birmingham)* To investigate the role of genetic heterogeneity of extracellular ATP-induced macrophage death and intracellular mycobacterial killing in conferring resistance to mycobacterial disease, by comparing P2Z
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'ARISE inspiring demand for sustainable energy skills, by providing clear learning interactions, transparency of upskilling transactions and recognition of qualifications achieved.' (ARISE), addressing dissemination and exploitation.

assistant: **Impact**

ARISE is developing a EU wide distinguishable recognition scheme of digital energy efficient BIM construction skills linked with a maturity-based digital ranking system for accounting CPD based learning transactions. The open competency based qualification scheme based on maturity levels that empower micro-learning will be the basis for making learning transactions count.  The project team will be gathering and linking BIM modules, tools and materials with the aim to establish a BIM resource and skills recognition pathway that all stakeholders can utilise, deliver and stimulate. This will provide BIM Energy performance alliance (BIM-EP) partners and other stakeholders with an e-learning materials repository to contribute to, whilst also developing a CPD recognition pathway for the whole supply chain to access and utilise.ARISE will revolutionise the learning process by developing a crypto-skills exchange, monetizing the skills and learning interface with a system based on skills recognition rather than accreditation. The reward of acquiring a competence at a certain level will be CERTcoin the innovative currency of skills and learning of the construction sector embracing today’s digital transformation benefits. This reward based on skills and time credits will be stored in an Individual learning Account and can be used as digital points accumulation in a skills barometer or for exchanging it into valid micro certificates. This will be an industry driven, easier accessible, less time consuming, highly competitive way to up-skill blue and white collars and increase vocational mobility.ARISE will complement and integrate with other existing projects, instruments and initiatives to deliver increased levels of sustainable energy skills across the entire supply chain of the c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Efficiency of innovation policies in high technology sectors in europe' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

A number of different policies have been developed in Europe, aiming at facilitating the scientific and commercial development of high technology sectors. A key question is how efficient these policies have been. This study addresses this question by exploring policy impacts across Europe on the development of a specific high technology area, namely biotechnology in all member states. The study will analyse policy effects on the performance of different actor types that are crucial for a prospering biotechnology innovation system. This will be achieved through in-depth country case studies that will elaborate qualitative and quantitative performance indicators and link those to policy effects, and cross country actor performance analyses. The results will provide a sound basis for conclusions and recommendations on best practise innovation policies in Europe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Integration of TRANSport and urban FORM In the European region of Strasbourg' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Land use and transport are closely related to one-another. The complex interactions of structures on local and regional level determine largely every day mobility behaviour. Processes of planning and implementation, however, seem to lack accuracy to control location development at transport nodes according to sustainability issues. The objectives of the project therefore focus on a) the analysis of impacts of urban form and function on mobility and transport (effectiveness of structures) and b) the development of methodologies and tools to improve regional planning, cooperation of actors and local implementation (efficiency of processes). Based on an international state-of-the-art and on a comparision of European best practices, the urban region of Strasbourg is chosen as a case study. An analysis of regional and local structures as well as of the underlying planning decisions is at the core of exploring the scope of possible measures and tools. On a conceptualisation level, the experimental development of a regional master plan on location development at transport nodes will be built upon this analysis. It is followed and tested by local implementation on specific project realisations. Feedback between practical implications on regional and local level as well as scientific assessment enable an evaluation and generalization of measures and tools for the Europe of Regions". From a methodological point of view, a System Thinking approach will be of interest for describing, estimating and assessing the interaction on the levels of impact and process. The partnership of INSA de Strasbourg as participant and ADEUS as local partner institution will induce a promising implication of scientific excellence and practice experience to boost knowledge on interaction and impacts, t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'MUCKY: The circular solution for the valorisation of mixed municipal waste streams.' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

In Europe, each year 250 Mton municipal waste streams (MWS) are produced of which about 55% is non-recyclable and currently dumped on landfills or incinerated. Current state of the art does not offer a solution for upgrading this deteriorated, low quality mixed waste streams without the need of intensive (pre)treatment.The main objective of the overall innovation project is to provide a technical solution, the Mucky, for turning mixed MWS into valuable linear hydrocarbons as a new resource for the chemical industry. The Mucky is not based on pyrolysis. Instead the uniquely dimensioned reactor of the Mucky allows controlled thermal cracking of the mixed waste into linear hydrocarbons up to 20 carbon atoms, giving syngas and solid minerals as side-products in a ratio of roughly 50 : 49 : 1. Landfilling of MWS gives a loss and incineration gives a value return of at best € 25/ton. The Mucky outperforms this by far, leading to an added value of around € 90/ton.The key market for the Mucky consists of all public and private municipal waste chain companies in Europe. The long term ambition of Bi-Energy is the conversion by Mucky of at least 50% of all carbon based, non-recyclable MWS, starting with the introduction of 100 Mucky installations in Europe before 2020. The total potential market consists of 51,500 Mucky units, each processing 2.5 ton of dry waste a day.In this feasibility assessment the final hurdles will be taken towards an Europe wide market introduction supported by convincing demonstrations of the Mucky installation at 10 representative locations. The final hurdles for establishing technical feasibility are obtaining an EU wide accepted certification and reducing manufacturing time and cost of the Mucky. The economic viability depends on solving legal issues,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Next generation, high performance, long range, standoff, concealed threat detection system to protect European citizens and critical infrastructure' in the context of a Horizon 2020 call.

assistant: **Objectives**

Acts of terrorism aim to instil fear into Europe's citizens. Since 2000, approximately 163,000 people have died from global terrorism. In particular, attacks against citizens and urban soft targets have increased as terrorists exploit the ability of autonomous cells and lone individuals to hit civilian targets such as concerts, markets, shopping malls, airports, transport hubs, sports stadia, cinemas, bars, night clubs and tourist resorts. Recent devastating attacks across Europe clearly illustrate the increasing threat that exists. It is impossible to deploy security personnel in sufficient numbers to protect every location. Even if security personnel are present they currently lack the technology to detect, at a safe range, concealed threats such as person borne improvised explosive devices (PBIEDs), guns and knives. There is an urgent and growing need for a cost effective, high performance, long range, concealed threat detection system. Radio Physics Solutions Ltd has developed MiRTLE (Millimetre-wave Radar Threat Level Evaluation), the world’s first, high performance, long range (up to 50m), low cost, standoff “concealed threat” detection system for the protection of citizens and critical infrastructure. MiRTLE is capable of screening large groups of people automatically and autonomously, without operator intervention, in real-time. Our highly innovative system detects PBIEDs, guns (including 3D printed) and knives up to a range of 50m in real-time, with targets in motion, all without privacy concerns. The overall objective of this project is to successfully refine, scale-up and demonstrate our superior technology to our customer base. We are planning to capture an 8% market share of the improvised explosive devices (IED) and weapon detection market, which will in t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'in situ Structure Determination of Actin-binding Proteins Through a Novel Cryo-electron Microscopy Workflow' in the context of a Horizon Europe call.

assistant: **Objectives**

Cell motility is driven by a complex network of force-generating biological machinery. The key component in this machinery is the dynamic network of filamentous actin (F-actin) and actin binding proteins (ABPs) which maintain and regulate the network. However, structural information for many ABP-actin complexes, as well as their in situ spatial distribution remain elusive. This is because ABPs cannot be easily studied in isolation, often exhibiting structural stability only when embedded in a complex filamentous network found within cells. This has hindered a complete understanding of actin network regulation in cell migration. Addressing this important question requires understanding exactly how ABPs select F-actin, and conversely how F-actin geometry recruits specific ABPs. Cryo-electron tomography (cryo-ET) can reveal both cellular ultrastructure and molecular details, but often is lower resolution than a single particle cryo-EM approach. Thus, innovative methods remain key to drive advancement in understanding in situ structures. In this fellowship I will combine my expertise of single particle cryo-electron microscopy with expertise of cryo-ET in the Schur lab to develop a novel hybrid single particle cryo-ET approach in order to reveal high-resolution structures and contextual information of ABPs bound to F-actin directly within cellular protrusions. ISTA is the ideal research institute due to abundant access to high-end electron microscopes necessary for methods development. The outcome of this action are tools for high resolution in situ structure determination and a better understanding of cell migration, a process deeply rooted in malignant metastasis. Results will be disseminated through key research conferences and high-impact open-access publications. Commu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'HEAT THROUGH A CONVENTIONAL HEAT EXCHANGER IN BAD ENDORF' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

The project already supported (GE./00128/94/DE) is running. The big amount of gas (1.2 m3/m3 of water) has to be separated before use for safety reasons and also to do not create problem while reinjecting after use. The gas is mainly methane and 94 Tons could be recovered to feed a gas engine of 65 kWe and 130 kWt power. The gas will be extracted from the water by using a vacuum pump and a scrubbing tower. The geothermal water itself will give its heat through a conventional heat exchanger and its temperature upgraded by a normal heat pump.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The Court of Elizabeth I – A European Drama' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The enduring fascination in anglophone research with the political culture of Elizabethan England has often served to occlude the fact that responses to the Tudor monarch were formulated across renaissance Europe. A pan-European range of dramatic texts bears witness to the anxiety and consuming interest which surrounded Elizabeth I. Such texts have often been neglected or referenced briefly as points of illustration. Moreover, these texts (where afforded any consideration) have most commonly been seen in terms of national traditions of literary production, rather than integrated into a Europe-wide vision of cultural debate and exchange. None of these texts has been considered in recent centuries for their theatrical potential or placed in close conversation with Elizabethan (or post-Elizabethan) literary production. This ambitious comparative project for the early modern period will be achieved through: close & comparative reading of primary texts; evaluative analysis of existing scholarship; consultation of host’s (Institute for Research on the Renaissance, the Neo-classical Age and the Enlightenment - Montpellier 3) and European archives; consultations with supervisor and advisory colleagues across Europe; engagement in performance-related events; e-networking with academic and non-academic audiences. In the course of this European project, Hiscock will: engage in a wholly transformative training in performance-based research and e-dissemination; produce cutting-edge research which embeds multilingual studies at the heart of early modern studies; disseminate research findings to a host of academic and non-academic audiences. This project engages tightly with the Marie Skłodowska-Curie Programme by: providing professional training in key skills for the applicant, thus
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Water resources modelling and management' (1998-2002).

assistant: **Concept**

In many applications, systems include both continuous and discrete components, discrete characteristics being also often introduced by the control system or its specifications. Such systems are commonly referred to as 'hybrid systems', and their understanding is rather limited at present. In practice, the control of hybrid systems is left to schemes based on heuristics rules deduced from practical plant operations. The aim of this work is to investigate the field of 'Mixed Logic Dynamical' systems, which seem an appropriate tool to model hybrid systems, then to examine related problems such as control, estimation and verification. Some current ideas for control and estimation are based on receding horizon predictive control and moving horizon state estimation. The 'three repositories system' was chosen M an implementation for the hybrid systems theory and the 'Mixed Logical Dynamical' models, because this case study can provide the necessary complexity for a simulation purpose. Starting from the theoretical results in Part 1, the aim of this work was to modify the simulations in order to feet a real case, a case of agricultural water management with three irrigation lakes. The objective wag to verify the opportunity of a control philosophy for the levels of the lakes based on the hybrid model. This can be further extended to more complex systems in water resources modeling, giving the chance of using flexible control laws in the management process, Taking into account the high computational load, a special attention was given to the optimization routine with the objective in finding a competitive methodology of solving 'Mixed Integer Quadratic Problems', the type of problem that is encountered In the predictive law for hybrid system in MLD form.