RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'New StOrage Latent and sensible concept for high efficient CSP Plants' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

NewSOL proposal addresses the specific challenge towards high efficiency solar energy harvesting by advancematerials solutions and architectures that are in line with those specified in SET-plan. Its main objective is to develop advance materials solutions based on innovative storage media and concepts for Concentrated Solar Power (CSP) up to validation in field of their performance by real time monitoring. This will be supported by an innovative thermal energy storage design based on the combination of new functional and advanced materials, like heat thermal fluid, sensible and latent energy storage media and insulating materials, into two innovative plant architectures: single tank thermocline storage and concrete type module. The main challenges of NewSOL are: Develop two new system Architectures: I) Thermocline Tank, (combining sensible and latent heat up to 550ºC), and II) Concrete module tank (sensible heat up to 550ºC). The scope to fulfil the challenges is to validate four new advance materials: 1) High thermal performance concrete (including carbon nanostructures), 2) Molten Salts (including nanoparticles), 3) PCMs, and 4) Filler Material re-usage.From the careful combination of the materials solutions within the two concept solutions six high relevant Impacts are expected: a) Reduced LCOE,10-12cEuro/kWh via higher material performance,b) New designs that enable a reduction of CAPEX and OPEX, c) Increase material understanding enabling long term performance,d)Deployment of high tech monitoring technologies included in the demo activities,e) Environmental re-usage of materials, and g) Through innovative materials, higher world market penetration of European materials supply sector.Moreover, investments foreseen at prototype level will be integrated into EMSP, pa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Social learning for the integrated management and sustainable use of water at catchment scale (SLIM)' (SLIM) under Fifth Framework.

assistant: **Objectives**

Water catchments are bundles" of natural resources and ecological services whose sustainable management requires continuous balancing and integration of social, economic and ecological factors in a complex process through statutory and non-coercive measures. "Social learning" is central to non-coercion (and important in the fulfilment of the EU Directive on Catchments Management) but its successful conduct needs to be much better understood. This reasoning applies equally to the co-management of natural resources of concern to the EU like national or coastal zones. The project assembles a multidisciplinary group of researchers of diverse perspectives to work alongside stakeholders. They will study social learning through stakeholders in catchments of different type, scale and socio-economic situation, and develop and test the usefulness of social tools and methods developed from their research and in other spheres, such as soft-systems analysis. The output will be strategic planning methodologies and social tools for the integrated management of water as catchments or river-basin scale and other "bundles" of natural resources."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Quantitative analysis of electrocatalytic reactions using transient voltammetry' (QUAER-TV).

assistant: **Concept**

This proposal aims to develop a rigorous quantitative framework for analyzing electrocatalytic reactions, addressing a critical gap between experimental studies and theoretical models in the field of electrocatalysis. The project will combine Fourier-transformed ac voltammetry (FTACV) measurements on single-crystal electrodes (SCEs) with Bayesian inference techniques to validate and test kinetic models describing electrocatalytic reactions.The objectives are to: (1) Validate kinetic models for simple electron transfer reactions on well-defined surfaces,  (2) Quantify the effects of reaction environment modifications on validated kinetic models, and (3) Extract with high-confidence reaction parameters for important electrocatalytic reactions like hydrogen evolution/oxidation and CO2 reductionThe innovative methodology integrates the high kinetic sensitivity FTACV, the well-defined nature of SCEs, and the statistical power of Bayesian inference. This combination will enable rigorous model validation, parameter estimation with confidence intervals, and quantitative comparison between competing models.By establishing clear validity boundaries for kinetic models and relating physical processes to model parameters, this work will strengthen the foundation for accurate model-experiment comparisons in electrocatalysis. The outcomes will be significant for developing more active, durable, and selective catalysts, as well as advancing theoretical modeling of electrocatalytic reactions.The project will contribute to the development of electrochemical technologies crucial for reducing the environmental impact of energy and chemical production.


**Keywords:** Single-crystal metal electrodes, Electrocatalysis, Fourier-transformed ac voltammetry, microkinetic modeling
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Single-cell genomics to comprehensively understand healthy B-cell maturation and transformation to chronic lymphocytic leukemia' (BCLLatlas).

assistant: **Innovation**

Unbiased analyses of the molecular make up of single cells are revolutionizing our understanding of cell differentiation and cancer. Over the last years, our groups have characterized the molecular features of normal B-cell subpopulations and of pools of leukemic cells from chronic lymphocytic leukemia (CLL), the most frequent leukemia in the Western world. These analyses have revealed that CLL subtypes are related to different B-cell maturation stages, and that they can show a complex subclonal architecture. Such subclonality is dynamically modulated during the course of the disease, and has deep implications in CLL biology, clinical aggressiveness and treatment responses. In this scenario, BCLL@las aims at deciphering the origin and molecular anatomy of CLL during the entire life history of the disease by generating genetic, transcriptional and epigenetic maps of hundred-thousands of single cells across locations, time points and individuals. We plan to fulfill four major objectives: 1) To generate a comprehensive atlas of normal B-cell maturation, 2) To understand the initial steps of neoplastic transformation through the analysis of minute B-cell monoclonal proliferations in healthy individuals, 3) To decipher the cellular diversity and clonal architecture of CLL at diagnosis, and 4) To characterize the single-cell subclonal dynamics of CLL during disease evolution and treatment response. To reach these goals, BCLL@las gathers together four teams with complementary expertise in B-cell biology, clinics and pathology of CLL, genomics, transcriptomics, epigenomics, sequencing technologies, single-cell profiling and computational biology. This, together with the richness of the available CLL samples and the technical and analytical depth of BCLL@las shall lead to unprec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Manipulation Enhancement through Robotic Guidance and Intelligent Novel Grippers' (MERGING), addressing dissemination and exploitation.

assistant: **Impact**

MERGING will deliver a turnkey robotic solution to automate handling of flexible and fragile objects.Our ambition is to provide manufacturers with an end-to-end solution to automate the handling of soft objects. The solution will consist of a fingered gripper equipped with an electro-adhesive skin that conforms to the objects to handle, even delicate fabrics or components, without any damage. Electro-adhesion increases the direct gripping forces and thus allows greatly reduced clamping forces. Our solution includes perception and supervision functions to adapt the system's behaviour in real time to the execution conditions and for robot system programming accessible to non-specialists.Our main motivations are to build a versatile, easy-to-use and low-cost system. To demonstrate this and the possibilities of scaling up, we will design our system using proven laboratory technologies (TRL 4), then carry out proof of concept in realistic environments (TRL 6) in three different applications and sectors: fabric handling for lingerie manufacturing, technical fiber handling for composite bus panel manufacturing, plastic bag handling for the food industry.MERGING is a four-year project involving the entire value chain of soft object gripping automation.The CEA leads the project and provides the robotic technologies in collaboration with EPFL (electrical adhesion), AIMEN (perception), LMS (supervision), and SHADOW then OMNIGRASP (capture) and IPC (materials). CEA, EPFL, AIMEN and LMS will respectively use AI technologies for robotic demonstration programming, electro-adhesive skin control, perception and control of the complete system. SELMARK, VDL and THIMONNIER introduce cases of use of fabric, composite and polymer handling respectively. CASP and OPTEAMUM are respectively resp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'IDEFIX Multiorgan toxicity and efficacy test platform' to be submitted under Horizon Europe.

assistant: **Abstract**

To address the critical problem of the failure of animal testing to predict drug effects (toxicity and efficacy) in humans, Cherry Biotech develops a breakthrough organ-on-chip/MPS solution based on microfluidic technology. Using human tissue, our IDEFIX technology mimics multiorgan physiology and physiopathology. Our MPS platform aims to be the new standard as an alternative to animal experimentation in preclinical studies. Indeed, our solution succeeds in tackling all major industry bottlenecks: seamless adaptability to current workflows, compatibility with all standard multiwell cell cultures and tissues, as well as full microenvironment control and measure while providing a state-of-the-art reconstruction of complex tissues (vascularisation, immune system, circulating metastasis, multiorgan interconnection). This is now achievable by combining the patent-pending gas mixers technology (FR2109230, TRL-3 coming from H2020-FET-OPEN project ELECTROMED) with Cherry Biotech proprietary microfluidic technologies in gas enrichment and simultaneous liquid flow (EP3712244; FR3094012; US2020299631) and our unique know-how in tissue engineering.Within the Transition project, the IDEFIX demonstrator will be completed as a modular platform, with stackable modules (gas, flow, temperature, biosensing, microscopy & imaging control), allowing users to customise the platform according to their respective needs and budget. The final qualification will be conducted in relevant environments, with two European pharmaceutical companies and a hospital/research centre using vascularized liver, adipose and breast cancer tissues. We will test our models to predict the efficacy and toxicity of various known molecules and compare them to previous preclinical animal experimentations and clinical r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Island biogeography of species interaction Networks.'.

assistant: **Objectives**

Islands hold ca. 20% of the global biodiversity but have suffered disproportionally high extinction rates and many extant species are threatened. The vulnerability of island biodiversity is linked to drivers of global change like habitat degradation, invasive species, and also climate change. The loss of biodiversity is problematic, since it affects crucial ecosystem functions, such as animal-mediated pollination and seed dispersal, and increases the risk of emerging diseases. However, despite their importance, islands remain largely understudied compared to mainland counterparts. Specifically, there is a lack of empirical studies investigating the effects of insularity and environmental factors, such as climate, on the structure of interaction networks and the underlying ecosystem functions. Furthermore, while parasite infections influence population dynamics, their impact on ecosystem functions has been overlooked. IslandNet will take a crucial step forward by analysing the first empirical dataset on bird-mediated ecosystem functions, in combination with data on functional traits and parasite infections across the islands of the East Caribbean. Combining network theory, functional ecology, island biogeography and parasitology, will allow to disentangle effects of insularity, environmental factors, functional diversity and parasite infections on network structure and underlying ecosystem functions across an entire archipelago. By contributing better insight into the mechanisms driving network structure across islands, IslandNet will provide essential knowledge allowing to plan conservation measures to prevent future biodiversity loss. During this fellowship, I will receive crucial training by leading experts in the fields of biotic interactions and island biogeography
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'innovative solutions for USER centric CHarging Infrastructure' (USER-CHI).

assistant: **Innovation**

USER-CHI aims at unlocking the massive potential of electromobility in Europe. This will be achieved by (1) integrating different innovative charging technologies with a holistic perspective, (2) putting the user at the centre and empowering it, (3) exploiting the synergies between electromobility and the process of greening and smartification of the grid which is taking place to achieve the energy transition in Europe, (4) integrating the technological tools, business models and regulatory measures which will transform the elements cited above into an actual, working ecosystem which improves the user experience of EV drivers beyond the current levels of ICE vehicles drivers, whilst at the same time makes financially attractive for the relevant private and public actors the large scale deployment of Europe’s required user centric charging infrastructure. USER-CHI will boost a large-scale e-mobility market take up in Europe, by means of developing integrated smart solutions, novel business models and new regulatory framework conditions, which will be demonstrated and validated in 5 urban areas all along the European territory: Barcelona metropolitan area (Spain), Rome (Italy), Berlin (Germany), Budapest (Hungary), and Turku (Finland). These 5 sites act as connecting nodes of the key Mediterranean and Scandinavian-Mediterranean TEN-T corridors, while their different sizes, complementary contexts and e-mobility maturity level offer a holistic view of e-mobility in Europe, facilitating the scalability and replicability of the demonstrated solutions.Since large scale replication and transferability of USER-CHI results is one of the cornerstones of the project, a replication city has been included in each of the TEN-T corridors involved in the project: Murcia (Spain) in Medit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The importance of gene and genome duplications for natural and artificial organism populations' under Seventh Framework.

assistant: **Concept**

The long-term establishment of ancient organisms that have undergone whole genome duplications has been exceedingly rare. On the other hand, tens of thousands of now-living species are polyploid and contain multiple copies of their genome. The paucity of ancient genome duplications and the existence of so many species that are currently polyploid provide an interesting and fascinating enigma. A question that remains is whether these older genome duplications have survived by coincidence or because they did occur at very specific times, for instance during major ecological upheavals and periods of extinction. It has indeed been proposed that chromosome doubling conveys greater stress tolerance by fostering slower development, delayed reproduction and longer life span. Furthermore, polyploids have also been considered to have greater ability to colonize new or disturbed habitats.  If polyploidy allowed many plant lineages to survive and adapt during global changes, as suggested, we might wonder whether polyploidy will confer a similar advantage in the current period of global warming and general ecological pressure caused by the human race. Given predictions that species extinction is now occurring at as high rates as during previous mass extinctions, will the presumed extra adaptability of polyploid plants mean they will become the dominant species? In the current proposal, we hope to address these questions at different levels through 1) the analysis of whole plant genome sequence data and 2) the in silico modelling of artificial gene regulatory networks to mimic the genomic consequences of genome doubling and how this may affect network structure and dosage balance. Furthermore, we aim at using simulated robotic models running on artificial gene regulatory networks in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'INNOVATIVE SPIRAL WOUND MEMBRANE MODULES FOR CROSS FLOW FILTRATION' (SPIRAL) targeting Fourth Framework.

assistant: **Abstract**

The project is focused on the exploitation of research results stemming from three projects carried out in the framework of BRITE programme. The projects, independently co-ordinated by SEPAREM and TECH SEP, were related to the development of a new microfiltration membrane, and the application of membrane technology to the textile industry and olive-oil production. The aim of the present proposal is to combine results of research carried out at TECH SEP and SEPAREM to develop respectively state-of-the-art microfiltration and ultrafiltration membranes, and spiral wound membrane modules.The novel products are intended to significantly advance the state-of-the-art of the current technology and consequently to increase the commercial potential of the two companies world-wide. In fact, due to the proven excellence of products singularly developed by the two companies (membranes and spiral modules) the products resulting from this proposal can strengthen the membrane industry and end-users which currently import from non-European countries more than US$ 27 Million per year of similar, but less efficient, membrane modules.The aim of this project was to develop novel ultrafiltration and microfiltration membrane modules and carry out pilot tests at end-users' sites to validate the application of the products in the following areas: concentration of human albumin and immonoglobines, treatment of milk and wey, treatment of wine and treatment of apple juices. The research area is very specialised and the project brings together research results developed by a French and Italian companies. This collaboration eases the risks and costs to enhance the competitiveness of these firms and hence to reduce reliance on non-European imports.The technology to be validated is expected to have im