RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Graphene based lubrication monitoring, lowering costs, improving ecology' under Horizon 2020.

assistant: **Concept**

Railways, road transport vehicles, wind turbines, manufacturing plants, all need targeted, adequate lubrication in order to function. At the same time, we are striving for greater protection of the environment. There is a push for ever greater efficiency, a move towards ecological products.Igralub and Graphenica lab are joining forces to develop a new field of products. Products that can sense the quality of the lubrication film from within. To do this, we want to apply the unique sensing properties of Graphene to the Tribology field. Our aim is to reduce the quantity of and reliance on oil based lubrication, to assist in the move to ecological lubricants. We want to drive a real breakthrough for lubrication.The market is vast with us targeting initial sales in the railway sector of 6M€ after 4 years from Market entry and increased employment across our joint venture of at least 12 additional employees by 2025. We propose an SME Instrument phase 1 project to assist us with a client-side pilot for the technology, as well as increased research regarding needed stakeholders and our overall business planning.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Nanoimprinting technologies for selective recognition and separation' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

It is widely accepted that molecularly imprinted polymers will be one of the most important technological and scientific challenges in the fields of biotechnology, separation, purification, analytical science, catalysis, biomdical and environmental applica tions. Particular advantages to be realized by MIPs are the low preparation cost and the potential utility in situations where no recognizing biomolecule is available. The present NANOIMPRINT" proposal addresses the following S&T objectives: 1. Novel synthesis routes for the economically feasible production of MIPs, taking into account limitations of the current synthetic approaches, and the rational design of improved imprinting materials. 2. MIPs for selective recognition and separation of biological molecules. Development of MIPs for selective recognition and separation of biological materials, utilizing reagents and polymerization techniques for delicate molecules such as oligosaccharides, peptides and for large structures such as proteins. 3. Carbo hydrate imprinted polymers as enhancers of bioactive compounds in microbial cultures. 4. MIPs as artificial receptors. Production of artificial receptors with high substrate selectivity and specificity for analytical science applications (immunoassays, chr omatography, capillary electrophoresis and solid phase extraction). 5. Understanding the mechanisms controlling the molecular structure. The present consortium combines the expertise of academic and research scientists (i.e., three university departments, four research institutes) in complementary scientific and technical areas with the business focus of one SME aiming to promote collaborative research and technology developments in biotechnology, environmental control, bioseparation, enzyme technology and biochemica
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Advanced noise reduction systems' to be submitted under Sixth Framework.

assistant: **Abstract**

Today noise still belongs to the most concerned environmental pollutants. This is an essential societal problem, and-transportation is seen as the primary source. Accepting mobility as a basic human need and as an essential precondition for maintaining economic prosperity and wealth in an enlarging Europe, it is clear that the adverseeffects of noise must be reduced while facing a continued increase in freight and passenger transport. CALM II aims at the synchronisation and encouragement of European transport noise research through an holistic system approach involving all related research areas. It is designed to facilitate the networking of organisations, the co-ordination of activities and the exchange and dissemination of knowledge. CALM II will > optimise research efforts > identify synergies between noise research objectives > identify remaining research needs > check the actual state-of-the-art of noise abatement technologies and support their industrial implementation By involving the most relevant stakeholders from European and national activities from road, rail, aeronautic and maritime transport as well as complementary research issues such as health and socio-economic aspect, the European Noise Working Groups and the respective European Research Advisory Councils, CALM II will support the European Commission in setting up the agenda for future transport noise research and development. The outcome will be published in the form of Community Noise Research Strategy Plans" and the CALM II Consortium will use all modes of modern communication, electronically as well as brochures, papers, presentations and discussions at events to disseminate the results and enhance the Coordination of European noise research. Altogether CALM II will essentially contribute to the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'ENERGY EFFICIENT REFURBISHMENT OF LAVRIO INDUSTRIAL HISTORICAL BUILDING COMPLEX' in the context of a Fourth Framework call.

assistant: **Objectives**

Energy efficient refurbishment integrating innovative renewable energies technologies and RUE (Expected energy saving : 774.3 Mwh/y, estimated annual monetary value saved : 43000000 GRD/y, expected of CO2 emissions : 50%, estimated payback : 10 years)- Reduce of energy consumption and CO2 emissions- Protection of the environment- Social and economic impact on the degraded area of Lavrio and creation of new labor market- Gaining the necessary expertise for other similar projects.The first part of the Manufacture, Assembly, Installation and Erection phases of the project which includes the construction of the innovative metallic roof with the incorporated Solar Air Heating System has been completed. Also, the exterior site work is completed. Finally, tendering procedure for the E-M part and the remaining construction works to complete the project is ready to begin.The project concerns the energy efficient refurbishement of an industrial - historical building at Lavrio. For this purpose innovative RUE and RES technologies will be integrated. For the production of the required thermal energy for heating and cooling, a small scale cogeneration unit (CHP), using natural gas, will be installed and at the same time, it will produce the appropriate electrical energy for the needs of the building. The energy surplus will be used by the neighbouring buildings. The heating of the space will be obtained by the recirculation of the air through the ducts in the walls which will be insulated and the insulated roof where a solar air heating system will be constructed. Additionally to this method, the air will be also heated by the CHP unit. The cooling will be obtained by absorption chillers using recovered heat from the cogeneration unit. The lighting of the building will be obtained b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Characterisation of DNA Double-Strand Break Repair by Alternative End-Joining:  Potential Targets for Cancer Therapy' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

DNA repair pathways evolved as an intricate network that senses DNA damage and resolves it in order to minimise genetic lesions and thus preventing tumour formation. Gaining in recognition the last few years, the alternative end-joining (alt-EJ) DNA repair pathway was recently shown to be up-regulated and required for cancer cell viability in the absence of homologous recombination-mediated repair (HR). Despite this integral role, the alt-EJ repair pathway remains poorly characterised in humans. As such, its molecular composition, regulation and crosstalk with HR and other repair pathways remain elusive. Additionally, the contribution of the alt-EJ pathway to tumour progression as well as the identification of a mutational signature associated with the use of alt-EJ has not yet been investigated. Moreover, the clinical relevance of developing small-molecule inhibitors targeting players in the alt-EJ pathway, such as the polymerase Pol Theta (Polθ), is of importance as current anticancer drug treatments have shown limited effectiveness in achieving cancer remission in patients with HR-deficient (HRD) tumours. Here, we propose a novel, multidisciplinary approach that aims to characterise the players and mechanisms of action involved in the utilisation of alt-EJ in cancer. This understanding will better elucidate the changing interplay between different DNA repair pathways, thus shedding light on whether and how the use of alt-EJ contributes to the pathogenic history and survival of HRD tumours, eventually paving the way for the development of novel anticancer therapeutics. For all the abovementioned reasons, we are convinced this project will have important implications in: 1) elucidating critical interconnections between DNA repair pathways, 2) improving the basic unders
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Reconstructing and modelling the history of the El Niño Southern Oscillation Phenomenon Throughout the Holocene'.

assistant: **Innovation**

Compound-specific hydrogen isotope ratios (dD) of biomarker compounds (e.g. n-alkanes, fatty acids, sterols etc.) have recently emerged as a new tool to track changes in the water cycle over the geological past. The proposed project will apply this new palaeoclimate proxy for the first time to reconstruct the dominant mode of global climate variability on multi-year timescales, the El Nino Southern Oscillation phenomenon (ENSO) throughout the Holocene. To achieve this objective lake sediment cores from Islands in the Tropical Pacific, where ENSO events dramatically alter precipitation patterns and therefore the isotopic composition of meteoric water, will be recovered and analysed for their biomarker dD values. The sites cover the entire Tropical Pacific Region, from Indonesia via Galapagos to the South American West Coast. This approach will result in the first direct reconstruction of ENSO variability throughout the Holocene.The reconstructed meteoric water dD values for specific time periods, where significant changes occur, will be evaluated using a state-of-the art Global Circulation Model (GCM) with a built in water isotope module (ECHAMiso). By variation of the models input parameters the climate of the selected time periods will be simulated. Comparing the models¿ predicted isotopic composition of the meteoric water with the reconstructed values, we will be able to identify the main forcing mechanisms of ENSO in the Holocene. The proposed project features a bottom-up organic geochemical reconstruct ion approach, using a recently available novel climate proxy and a top-down modelling approach, using an advanced GCM with built in water isotope diagnostics. Combining these two novel approaches will greatly improve our understanding of ENSO variability and its cause
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Quantum Optical Control' (QOCO).

assistant: **Innovation**

This proposal details the planned incorporation of femtsecond pulse shaping and coherent control strategies into the repertoire of continuous variable quantum optics with the explicit goals of both manipulating and analyzing nonclassical, multimode structures. Since multimode entanglement is a prerequisite for numerous applications in quantum metrology and quantum information science, femtosecond optical frequency combs, which are inherently multimode, are a promising candidate for the development of such states. Toward this end, optical parametric oscillators have proven effective for the creation of multimode quantum frequency combs, and the further introduction of pulse shaping strategies will follow a two-pronged approach. First, shaped pulses will serve as an interrogative probe that enables complete characterization of the nonclassical properties of individual modes comprising the total state. Subsequently, the shaping of the femtosecond pulses that drive the parametric interaction will allow active manipulation of the multimode entanglement. The on-demand customization of nonclassical multimode states is expected to be an essential resource in the continued development of continuous variable quantum optics.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Study of the Planetary Human-Environment Relationship: The Rise of Global Environmental Governance' (SPHERE).

assistant: **Concept**

SPHERE is a historical study of humanity’s relation to planetary conditions and constraints and how it has become understood as a governance issue. The key argument is that Global Environmental Governance (GEG), which has arisen in response to this issue, is inseparable from the rise of a planetary Earth systems science and a knowledge-informed understanding of global change that has affected broad communities of practice. The overarching objective is to provide a fundamentally new perspective on GEG that challenges both previous linear, progressivist narratives through incremental institutional work and the way contemporary history is written and understood. SPHERE will be implemented as an expressly global history along four Trajectories, which will ensure both transnational as well as transdisciplinary analysis of GEG as a major contemporary phenomenon. Trajectory I: Formation articulates a proto-history of GEG after 1945 when the concept of ‘the environment’ in its new integrative meaning was established and a slow formation of policy ideas and institutions could start. Trajectory II: The complicated turning of environmental research into governance investigates the relation between environmental science and environmental governance which SPHERE examines as an open ended historical process. Why was it that high politics and diplomacy came in closer relations with environmental sciences? Trajectory III: Alternative agencies – governance through business and civic society explores corporate responses, including self-regulation through the concept of Corporate Social Responsibility, to growing concerns about environmental degradation and pollution, and business-science relations.Trajectory IV: Integrating Earth into History – scaling, mediating, remembering will turn t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'First Biodegradable Biocatalytic VascularTherapeutic Implants'.

assistant: **Concept**

We aim to perform academic development of a novel biomedical opportunity: localized synthesis of drugs within biocatalytic therapeutic vascular implants (BVI) for site-specific drug delivery to target organs and tissues. Primary envisioned targets for therapeutic intervention using BVI are atherosclerosis, viral hepatitis, and hepatocellular carcinoma: three of the most prevalent and debilitating conditions which affect hundreds of millions worldwide and which continue to increase in their importance in the era of increasingly aging population. For hepatic applications, we aim to develop drug eluting beads which are equipped with tools of enzyme-prodrug therapy (EPT) and are administered to the liver via trans-arterial catheter embolization. Therein, the beads perform localized synthesis of drugs and imaging reagents for anticancer combination therapy and theranostics, antiviral and anti-inflammatory agents for the treatment of hepatitis. Further, we conceive vascular therapeutic inserts (VTI) as a novel type of implantable biomaterials for treatment of atherosclerosis and re-endothelialization of vascular stents and grafts. Using EPT, inserts will tame “the guardian of cardiovascular grafts”, nitric oxide, for which localized, site specific synthesis and delivery spell success of therapeutic intervention and/or aided tissue regeneration. This proposal is positioned on the forefront of biomedical engineering and its success requires excellence in polymer chemistry, materials design, medicinal chemistry, and translational medicine. Each part of this proposal - design of novel types of vascular implants, engineering novel biomaterials, developing innovative fabrication and characterization techniques – is of high value for fundamental biomedical sciences. The project is t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Small and Medium Sized Enterprise Alliance through Research in Tourism - Take up.' (SMART-UP), addressing dissemination and exploitation.

assistant: **Impact**

SMART-UP provides small and medium sized tourism enterprise (SMEs) with up-to-date tourism management know-how through modern information technologies. In the first trial, selected SMEs will test a first version of SMART-Up which integrates the SITOS learning tool with agent Technology. The participating universities design a total of five learning modules over the lifespan of the project which will be complemented by dynamic information collected by web-search agents, constantly updated benchmarking solutions, and chat facilities. In the second trial, the improved version of SMART-Up will be tested by a larger group of SMEs in order to finally create a learning tool that ensures a fast and cheap know-how amongst tourism SMEs and knwo-how producers (e.g. universities) throughout Europe.Objectives:The main goal is to alleviate know-how gaps of SMEs in tourism in the use of IT and specified areas of tourism management, thereby rendering the enterprises more competitive. This will also benefit tourists through an improved value of tourism services. The SMART-UP network also provides a learning platform to foster the use and acceptance of the latest available IT. The project aims at creating a low cost, easy to access knowledge co-operation of know-how providers and SMEs throughout Europe, thus increasing the innovation potential. Technical objectives include the dissemination of the Intelligent Agent Technology in the field of education and training in tourism, and the design of a flexible learning tool that allows individual and constant adjustments to users needs. The main business goal is to initiate a widely accepted learning platform for European tourism SMEs.Work description:The proposed work schedule starts with the selection of 75 suitable tourism SMEs in Austria,