RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Citizen-Oriented Valorisation for Advancement, Learning and Uptake in Europe' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The overall objective of CO-VALUE is to boost uptake and deployment of research results by adopting a co-valorisation approach that strengthens the role of societal actors in knowledge valorisation. Citizen engagement will be embedded in knowledge valorisation by deploying capacity building, peer learning actions and experimentation. CO-VALUE will capitalise on and contribute to EU initiatives such as the Knowledge Valorisation Platform, through the production, testing and improvement of best practices and lessons learned in two European territories: Alicante in Spain and Emilia Romagna in Italy. In each territory, quadruple-helix stakeholders from the research & innovation ecosystem will be involved in the co-design and implementation of co-valorisation, exploiting ongoing knowledge valorisation processes such as developing innovative solutions to address the lack of raw materials and its impact on citizens’ welfare (Alicante), or specific funding schemes and projects to introduce multi-stakeholder engagement in public-funded research (Emilia Romagna).The transfer of best practices and skills will be guaranteed by a comprehensive scheme of capacity building, peer learning and shadowing opportunities, both at local and international level. The involvement of umbrella organisations such as EBN, ERRIN and universities alliances will foster a wider uptake of CO-VALUE’s trainings and tools, thus supporting the implementation of new practices by knowledge valorisation agents beyond the project consortium. Incentives for researchers to engage with society, and for society to engage with researchers will be co-designed with stakeholders in each territory and implemented throughthe involvement of local R&I public administrations. Tangible changes in local co-valorisation agents
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Attitudinal change in troubled times: A triangulation strategy' under Seventh Framework.

assistant: **Concept**

Comparative political behaviour research studies the impact of individual and contextual characteristics on citizens’ political attitudes and behaviour. Typically, researchers use cross-national survey data and country-level data to examine how economic, political, or institutional contexts affect the outcomes of interest. However, conventional identification strategies suffer from omitted variable and reverse causation problems, which hinder the ability of researchers to assess causal claims.To help overcome these problems, this project will develop, apply, and disseminate a novel triangulation strategy that combines three methodologies:a)The analysis of cross-national survey data to establish external validityb)The design of original survey experiments to assess the internal validity, i.e. if there is a cause and effect relationship between the variablesc)The use of case studies to trace mechanismsThe triangulation strategy will be applied to study how three contextual features that are very relevant in the current European environment generate attitudinal change:a)The effect of income inequality on pro-social attitudesb)The effect of an economic depression on attitudes towards democracyc)The effect of electoral procedures and voter turnout on governmental legitimacyOne main aim is to promote the use of multi-method approaches and experiments in European political behaviour research. To achieve this, the project foresees the collection of original experimental data, the organization of at least two academic dissemination activities, and the organization of courses on survey experiment design.The substantive results are of interest to the general public. The project will disseminate them through a website, the write-up of a general audience book, and through several ne
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Measuring and Understanding Disparities in Family Formation in Low- and Middle-Income Countries'.

assistant: **Objectives**

The first union formation and the birth of the first child are among the most critical events shaping men’s and women’s life-course trajectories. Sustainable Development Goals (SDG) stress that all individuals should have access to means that allow them to control their fertility and should be able to marry at an age that does not harm their development capabilities. Central to SDGs is eradicating disparities in the timing of family formation, yet the understanding of their global patterns and determinants is limited, particularly in low- and middle-income countries (LMICs). This is a critical research gap as many women in LMICs enter their first union and become mothers very early in life and much earlier than men, which puts them at risk of adverse health outcomes. Focusing on 69 LMICs this project aims to radically improve our understanding of global family changes by providing novel empirical evidence on a critical yet poorly understood topic. Namely, using nuanced indicators, I will deliver the first-ever global examination of changes in disparities in the timing of family formation, both within and between the populations of women and men. Subsequently, I will investigate the role of an under-research dimension of education - schooling quality – and the role of gender inequality in opportunities in driving these disparities. This project will straddle the disciplines of demography, sociology, and international development to produce cutting-edge research that will improve the scientific understanding of social inequalities. By delivering novel evidence about the role of educational and gender inequalities in shaping young adults’ family formation trajectories, this project will be of value to the wider research and policy community, including organizations such as
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Mechanisms of Influenza virus assembly and budding', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Influenza virus is an enveloped virus of significant medical importance.  One of the least understood aspects of influenza virus biology is the process of virus particle assembly and budding.  Recently we have found a new role for the cytoplasmic tail of the influenza virus M2 protein, the mediation of membrane scission.  The research described in this proposal is designed to elucidate the molecular mechanisms of influenza virus assembly and budding as mediated by the M2 protein.This research has three main objectives:1.To determine the structure and function of the M2 cytoplasmic tail2.To determine the molecular mechanism by which the M2 amphipathic helix alters membrane curvature3.To analyze and reconstitute influenza virus budding in vitroEach of these objectives will be addressed using a similar collection of experimental protocols.  To better elucidate the functions of the M2 cytoplasmic tail, mutations will be made throughout the region and incorporated into recombinant viruses.  These mutants will then be assessed for function through a variety of assays including: viral assays (growth rate and budding efficiency), protein assays (cholesterol association, protein localization and ion channel activity) and in vitro budding assays performed in giant unilamellar vesicle systems.  These functional studies will be supported by structural studies of the M2 cytoplasmic tail, as obtained by NMR, and modelling of M2 amphipathic helix-membrane interactions by molecular dynamics simulations.The successful completion of this research project will inform as to the structure and function of the M2 cytoplasmic tail.  This research has significant implications in the understanding of influenza virus assembly and budding, establishes an in vitro model system for the investigation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Improvement of marama bean (tylosema esculentum (burch.) schreiber) an under-utilized grain and tuber producing legume for southern africa.'.

assistant: **Innovation**

Marama bean (Tylosema esculentum L.), an under-utilised, perennial legume of poor, arid soils of southern Africa, produces protein- and oil-rich, edible seeds (harvested wild) and extremely large (up to 200 kg) tubers, containing protein and carbohydrate: Its foliage provides fodder. This project will assess the potential of marama as a low-input, sustainable crop for subsistence agriculture in dry areas. Distribution in the wild and biodiversity will be assessed. Agronomic trials with varying water and nitrogen will assess growth, yield and quality of grain, tubers and foliage in relation to environmental conditions. Scientific understanding of the mechanisms by which marama accumulates nitrogen and carbon, partitions assimilates to organs and withstands stresses, particularly watercress, will come from physiological and biochemical analysis of plants in experiments. The project will foster the use of marama and its agronomy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Study for the establishment of a network of competent partners for the treatment and the energy valorisation, by means of anaerobic digestion, of the residues generated by the citrus-processing industries', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

A large number of citrus-fruits processing industries generate significant quantities of organic residues, the current practice for their disposal being uncontrolled landfilling. One of the methods best suited to treat such organic, wet residues is that of Anaerobic Digestion (AD) to produce biogas (to generate electricity and heat) and compost (to be used a an added-value soil conditioner/fertiliser).Since, most of the times, the involved industries and SMEs do not meet the critical size to ensure a financially viable energy valorisation of their organic residues, it is vital to combine the waste streams of different SMEs as well as involve competent partners with different disciplines (i.e. technology vendors, specialised contractors and finance providers).The proposed study includes the effective networking" of such partners to examine, address and deal with the proposed project non-technical issues, which have been found to be of paramount importance to the successful launching of similar undertakings, these being:* the exact identification and role of the key players involved in the actual implementation of the proposed undertaking (and other similar applications)* the assessment and quantification of social and environmental impacts related to project appraisal* the identification and perception of all risks associated with the proposed (and other of similar nature) project deployment as well as the exact set-out of all measures and actions for the identified risks minimisation* the establishment of the exact financing structure of the proposed project as well as the identified "networking" activities* the formulation of a precise Business Plan at a very early stage of the entire undertaking.The proposed study includes an integrated approach not only for the ratio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Guided Nanowires: From Growth Mechanism to Self-Integrating Nanosystems', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The large-scale assembly of nanowires (NWs) with controlled orientation on surfaces remains one challenge toward their integration into practical devices. A recent paper in Science from the PI’s group reported the guided growth of millimeter-long horizontal NWs with controlled orientations on crystal surfaces. The growth directions and crystallographic orientation of GaN NWs are controlled by their epitaxial relationship with different planes of sapphire, as well as by a graphoepitaxial effect that guides their growth along surface steps and grooves. Despite their interaction with the surface, these horizontally grown NWs have surprisingly few defects, exhibiting optical and electronic properties superior to those of vertically grown NWs. We observed that whereas in a 2D film stress accumulates in two directions, in a NW stress accumulates along its axis, but can relax in the transversal direction, making the 1D system much more tolerant to mismatch than a 2D film. This new 1D nanoscale effect, along with the graphoepitaxial effect, subverts the paradigm not only in the young field of NWs, but also in the established field of epitaxy. This paves the way to highly controlled semiconductor structures with potential applications not available by other means.The aim of this project is to investigate the guided growth of NWs and unleash its vast possibilities toward the realization of self-integrating nanosystems.First, we will generalize the guided growth of NWs to a variety of semiconductors and substrates, and produce ordered arrays of NWs with coherently modulated composition and doping.Second, we will conduct fundamental studies to investigate the correlated structure, growth mechanism, optical and electronic properties of guided NWs.Third, we will exploit the guided gr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Advanced manufacturing of drug substances by co-processing with excipients through heteronucleation in a milifluidic device'.

assistant: **Innovation**

Pharmaceutical industry is starting to adopt the approach of continuous manufacturing, with as few unit operations as possible, to deliver drug products in a faster, robust, cheaper and sustainable way. Poor mechanical properties of many drug substances are a hindrance to this, making them unsuitable for direct compression into tablets without additional operations.  This challenge can be solved by co-processing: joining the particles of such drugs to the particles of inactive substances known as excipients (e.g. lactose), normally used for tablets production. The aim of this project is to develop a universal drug-excipient co-processing (CP) platform based on surface crystallization or co-precipitation. A CP method in a milifluidic device will be optimised with a range of drugs with differing physicochemical properties. The relationships between them, as well as excipient properties, parameters of the method and structural and functional characteristics of the obtained composites will be thoroughly investigated. To this end, cutting edge techniques will be employed to analyse particle size, morphology, dissolution and mechanical behaviour. To demonstrate improved manufacturability, the prototype CP material will be used for direct compression, and the tablets quality will be evaluated according to European Pharmacopeia requirements. The project will enable the researcher to achieve professional maturity in the field of particle engineering, allowing to employ her skills both in academia and in pharmaceutical industry. The results of the research will have commercialisation value, being of interest to companies as a potential new platform in (pre)formulation portfolio. The project will contribute to the body of evidence informing the decisions of regulators on pharmaceu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Technically optimised pile concept (TOPIC)'.

assistant: **Innovation**

A growing pressure on environmental constraints obliges to rethink construction processes. New EC directives on protection of groundwater will soon oblige to review concrete formulations to avoid pollution potential to water resources.These social problems lead to the development of a new approach for the execution of foundations, with:- a new method of pile installation acceptable in urban environment, to minimise soil waste and improve the bearing capacity;- a quality assessment system, to control in real time the piling process and integrating an automated positioning of the machine and a remote control of the concrete (quantity, viscosity, regulation of the flow);- new formulations of concrete with an improved working stress, added with silica fumes, to eliminate the leaching potential of organic additives.The development will be supported by an extensive research to simulate (numerical model, small scale model) the drilling process. A field test will be organised at the end of the project to validate the research.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Intelligent control of fat crystallization using sensors and expert systems' in the context of a Fourth Framework call.

assistant: **Objectives**

Optimal process conditions In the oil and fat processing industry are often determined by time-consuming off-line blend characterization. Due to constant variation in product properties and change in raw material fat blends (up to 500 blende used) accurate process control is important. This is often initiated through manually product inspection by skilled operators. However irregular monitoring intervals and suboptimal process adaptations reduces the overall economic efficiency by the extra use of labour, raw materials and energy. A large amount of resources are involved: a total overall potential efficiency improvement of 250 Mecu in EC annually is estimated. For this reason there is a great industrial interest to have structural product-related expertise at their disposal. Compared with the (petro-)chemical, polymer and construction industry where innovative techniques as sensors, intelligent control systems (self-learning software), human expertise integration are applied on a large scale, the food processing industry is making less use of this innovative technology. Although the food processing industry has its own specific complexity, the adaptation and implementation of sensor techniques and intelligent control systems, successfully applied in other industrial processes, seem very challenging. The RTD goals to be reached in this research project are: * optimization of the fat crystallization process through the development of a product monitoring and intelligent control prototype system: * testing and implementation of the system under lab- and pilot-scale conditions; ' efficiency improvement in the oil and fat processing industry by better use of labour, raw materials and energy (estimated loss decrease by 50 %); The development and successful demonstration of an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Distributed and federated cross-modality actuation through advanced nanomaterials and neuromorphic learning' in the context of a Horizon Europe call.

assistant: **Objectives**

A vast number of pathological brain conditions directly involve aberrant electrical activity of the brain. CROSSBRAIN centres its technological revolution on the convergence of novel nanoactuation modalities, bleeding-edge nano-electronics, and miniaturized wireless energy harvesting and communication. Combining extreme edge computing with advanced nanomaterials featuring tailored physical properties, biocompatible coatings, and material modifications to prevent glial scarring, CROSSBRAIN will enable individualized, adaptive and highly spatiotemporally localized actuation of brain tissue. It will leverage sensing electric local field potentials, multiunit neuronal activity, and cross-modal nanomaterial-based modulation (electrical, mechanical, thermal, ionic concentration, optogenetics) of neuronal excitability with on-board intelligence. The CROSSBRAIN platform comprises a swarm of wireless, implantable, MRI-compatible microbots for in vivo electrophysiology and cross-modal neuromodulation at the cell- and microcircuit levels, in freely moving rodents. CROSSBRAIN delivers a multiplicity of stimulation modalities, involving electro-mechano-magneto-thermo-optical principles for modulation of nerve cell excitability. The microbots will feature both sensing and actuation electrodes, engineered with nanomaterials and viral vectors coatings. They will be implanted endovascularly, deliver genetic material upon command, and operate in federation under the networked control and wireless power supply by a tiny central unit, which can be worn like an internet of things device. CROSSBRAIN will deliver autonomous or manual, closed-loop sensing, prediction, and actuation through combining multiple neuromodulation mechanisms, which will act in a synergistic and dynamic manner to opti