RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'European Doctoral Training Support in Micro/Nano-electronics' (EURO-DOTS-2).

assistant: **Concept**

This proposal is submitted to support and ensure continuation of the EURO-DOTS initiative, that was launched as a Support Action in response to the FP7-Call 5 and that has successfully realized all the objectives resulting in the installation of a virtual platform to serve the Doctoral Schools in Europe in micro/nano-electronics. When the present 2-year EURO-DOTS project ends on 30 April 2012, it will not only have a fully operational platform and system in place, but it will also have realized the build-up of a course portfolio of nearly 50 PhD course titles, offered and organized by universities all over Europe. The major objective of EURO-DOTS was to improve the offering and quality of training provided to European PhD students in the micro/nano-electronics area based on the comprehensive analysis of university offering and industrial needs. One week intensive courses help them fulfilling the requirements for ECTS credits imposed by European universities for obtaining the PhD degree in Engineering. Essential in this endeavor are the scholarships that PhD students can apply for. This boosts the mobility of students but most importantly, it allows them to attend the right course at the right place, where the expertise on the treated subject is guaranteed.The major objective of this EURO-DOTS-2 follow-up project with a 2 year duration, is to ensure the continuation and continuity of the present successful action. This implies maintaining and improving operation of the platform, managing course portfolio and planning, stimulating development and submission of new courses in response to the needs of industry and researchers, managing and attributing of scholarships for PhD students and promotion of platform service and course offering. The present partnership, installed c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'High Frequency FET employing 2D materials for gas sensing'.

assistant: **Objectives**

Human safety and the protection of air quality would clearly benefit from the deployment of widespread, unattended, wireless networks with gas sensing capabilities. While the Internet of Things (IoT) is on the rise (3.2 billion devices connected by 2023), the 5G will improve IoT performance and reliability. The development of high frequency field effect transistors (HF-FETs) for wireless networks is fuelling the research in a new generation of high frequency electronics employing new nanomaterials. In this context, the HF2ET2D aims at the synthesis of two-dimensional (2D) materials and at the fabrication of HF-FETs in order to realize high frequency gas sensors for being integrated in the new generation of unattended gas sensor networks. Additionally, it aims at improving sensor performance (sensitivity and selectivity) by using surface functionalization and light excitation. 2D materials like black phosphorus, Indium Selenium (InSe) and Platinum Diselenide (PtSe2) are still very new materials, which deserve being investigated further. Their rich electrical-optical-gas sensing properties will allow us to fabricate high frequency FET gas sensors with superior performance. The crystalline quality of these materials, their good carrier mobility and high on/off current will affect the figure of merit of the HF-FETs (maximum frequency of oscillation and the cut-off frequency). Direct band gap, good light absorbance, and high photo-responsivity are interesting factors to enhance the electrical characteristics of the transistors and ameliorate the repeatability and drift issues often experienced with gas sensors. Ultra large surface to volume ratios, rich surface chemistry and favourable surface energy levels for gas adsorption will allow to obtain room temperature gas sensors
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Feasibility studies for speciated crms for arsenic in chicken, rice, fish and soil and selenium in yeast and cereal (SEAS)', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

The form of arsenic and selenium in food and environmental samples determine toxicity, bio availability and economic value. The feasibility of producing certified reference materials for controlling speciation measurements of As in chicken, rice, fish and soil and Se in yeast and cereal will be investigated. Expert laboratories will grow or collect suitable samples, conduct preliminary analyses and forward them to a leading producer of CRMs. The freeze-dried. powdered materials will be subject to homogeneity and stability testing according to agreed protocols. Materials shown to be suitable will be subject to an interlaboratory comparison exercise involving at least 10 expert laboratories to prove suitability for CRMs production. The candidate materials have been selected in response to industrial and regulators needs as presented to an EU network.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Bacterial Alkaloid Biosynthesis off the Beaten Path: Compartmentalization and Non-Enzymatic Transformations in Non-Canonical Alkaloid Biosynthesis'.

assistant: **Innovation**

Nature is a remarkable pharmaceutical chemist. More than 50% of approved drugs are natural products (NPs) or have drawn inspiration from them. According to the central dogma of bacterial NP biosynthesis all transformations responsible for the formation and modification of a NP scaffold are carried out by enzymes encoded in a biosynthetic gene cluster (BGC).Sophisticated genome mining algorithms have been developed to identify NP BGCs in microbial genome sequences. These algorithms excel in recognizing canonical BGCs. Non-canonical BGCs associated with NPs that are not biosynthesized following textbook biosynthetic knowledge evade detection by state-of-the-art genome mining algorithms. We have identified alkaloids that undergo non-enzymatic transformations, thus defying the central dogma of NP biosynthesis. Bacteria likely employ specialized micro-compartments to facilitate these spontaneous reactions.The ComBiNE team will develop machine learning-based genome mining algorithms to systematically identify and characterize alkaloid BGCs that currently elude detection. These non-canonical pathways biosynthesize alkaloids independent of the ribosome and non-ribosomal peptide synthetases. We will focus on alkaloids that undergo non-enzymatic transformations in bacterial micro-compartments. We will establish a model system to study the level of compartmentalization necessary to facilitate spontaneous reactions. Insights gained from these studies will be used to engineer NP and primary metabolic pathways for the non-enzymatic fusion of tailor-made NPs or primary metabolites with complementary reactivity.Spontaneous reactions in bacterial micro-compartments can be harnessed for the fusion of two NPs with different targets to create bispecific chimeras to combat drug resistance o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Mechanisms of the biodegradation in soil of biodegradable polymers designed for agricultural applications' in the context of a Sixth Framework call.

assistant: **Objectives**

The main objective of the project is to identify and get an in-depth knowledge about the basic mechanisms and the range of factors affecting the biodegradation in-soil process of selected biodegradable polymer materials designed for agricultural applications. A more thorough comprehension of the relationship between polymer composition and processing (of the selected materials) and the mechanisms of biodegradability in soil under various conditions is to be attained.The proposed fellowship aims at supporting a very promising and experienced female researcher with expertise in polymer chemistry from a new EU country to undertake training through a specially designed research project at the Agricultural University of Athens. The research topic has been chosen to offer the fellow a specialisation in a complimentary field most appropriate to her individual profile and needs for getting new knowledge and experience on the biodegradation mechanisms developed by selected biodegradable materials especially designed for agricultural applications.The research work of the fellow will add to her scientific competencies in a highly interdisciplinary field of agricultural engineering and environmental issues related to biodegradable polymers especially designed for agricultural applications, as well as some fundamental knowledge in soil sciences. The new knowledge and complementary skills and competences expected to be acquired will reinforce her professional maturity and independence in line with Fellows professional plans, as she plans to write a postdoctoral dissertation related to polymer materials based on renewable feedstock.The proposed fellowship project will also strengthen the intra-European research cooperation by creating links between two well established European resear
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'COMMERCIAL FEASIBILITY OF CONTROLLING MELON RIPENING THROUGH, GENETIC MANIPULATION OF ETHYLENE BIOSYNTHESIS', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

In the recent years, methods based on the genetic manipulation of fiuit ripening have been developed with the aim of increasing the storage life and improving the quality of fruits. For instance, the down regulation of tomato polygalacturonase (PG) gene expression by antisense RNA prevented pectin degradation and gave an improved shelf-life and thus technological qualities. Even though European laboratories have been the leaders in controlling fruit physiology through manipulation of gene expression, the commercial feasability of this strategy has up to the present been demonstrated only in the USA by the release into the US market of aIltisense PG tomatoes in 1994.All the studies reported so far have been carried out with the tomato as a model plant. The four partners of this project have previously collaborates within the Famework of an EC ECLA1R programme (AGRE 0015) to develop these technologies at the pre-competitive level, for another type of fzruit, the melon. Two pure lines of melon expressing an antisense ACC oxidase gene have been generated. These exhibit a strong reduction of ethylene production and a delayed ripening.The present project, placed under the coordination of an SME seed companyn consists of a demonstration programme aimed at releasing onto the market new commercial genotypes with a longer shelf-life and of better eating quality. These commercial genotypes with improved postharvest handling qualities are expected to enlarge the market for cantaloupe melons in Europe and improve the competitiviness of European producersThe programme will consist of: (i) characterizing in depth the agronomical traits of two transgenic melons expressing an ACC oxidase-antisense gene, (ii) generating commercial Fl hybrids by crossing these new genotypes with other gen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Assessment of the GTAP modelling framework for policy analysis from a European perspective', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The imminent changes in the Union's external relations face the European agricultural sector with a number of challenges. The prospect of a new round of trade negotiations and the perspective of enlargement increase the need to deepen the reforms of the Union's agricultural policies, as set out in Agenda2000. The outcomes of negotiation rounds such as WTO trade negotiations and the Kyoto environmental summit bear implications for European farmers, related supplying and processing industries and European consumers. The assessment of likely policy impact is bound to be complex and should be supported by quantitative modelling analysis that explicit the relations of European countries with third countries and that encompasses the relations between the agricultural sector and the national economies within the European countries.The proposal is to develop a network of researchers involved in international trade, resource and environmental modelling and who (potentially) use the Global Trade Analysis Project (GTAP) as tool of analysis.The objectives of the proposed work are: - to assess the usefulness of the GTAP framework for (global) issues that are of importance to the European Union. - to bring together European researchers who work on the field of global trade, I resource and environmental issues and who (potentially) use the GTA framework as tool of analyses.- to identify joint research proposals that actually apply the GTAP framework to European Issues. To achieve these objectives, a collaborative effort among European research institutions and academic institutions is proposed that sets out to:- asses the state of the art on international trade modelling and related resource and environmental modelling.- survey on-going research in which the GTAP framework (model and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Genetics, Geography and the Intergenerational Transmission of Maternal Depression Risk' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

We can all name a family member, close friend, colleague or acquaintance who has suffered from depression. It is a common, pervasive and devastating illness characterised by persistent episodes of low mood. Depression affects individuals across all geographical locations and by the year 2030 it will be the largest contributor to disease burden worldwide. Depression that occurs in women during pregnancy and post-partum is referred to as maternal depression (MD). MD is the leading cause of perinatal mortality and it accounts for ∼20% of all postpartum deaths.  Despite this profound individual and societal burden, the aetiology of depression remains poorly understood in part, due to three research barriers: 1) lack of success in identifying genetic variants specific to MD 2) inadequate account of environmental risk factors in genetic research and 3) heterogeneity. GenGeoRisk will address each of these research barriers in the following ways: 1) I will use aggregates of genetic variants (polygenic scores) derived from other successful studies of psychiatric traits to calculate genetic p—a general dimension, which sits at the top of a hierarchical structure of psychopathological dimensions and captures one’s general liability to psychopathology. Genetic p will be used to predict MD symptom risk and resilience in the world’s largest (N= 240 000) pregnancy cohort (MoBa; the Norwegian, mother, father and offspring cohort study) 2) I will use geographical location data from the entire Norwegian population (> 7 000 000) that has been recently linked to MoBa data to illuminate how MD symptoms and genetic p vary across neighbourhoods and diverse Norwegian municipalities  3) I will focus on MD, a less heterogeneous form of major depression, and use genetic p to discover MD subtypes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Stability and Instability in the Mathematical Analysis of the Einstein equations' (StabMAEinstein) under Seventh Framework.

assistant: **Objectives**

The present proposal is concerned with the global analysis of solutions to the Einstein equations of general relativity. This subject lies at the intersection of the analysis of partial differential equations, differential geometry and theoretical physics and is a field of intense current activity, with several important advances having been achieved in the last decade only.The main objective of the proposal is to establish a research group based at Imperial College to develop novel mathematical techniques that would allow one to move considerably beyond the current limits of the field. These techniques will be devised and mature in the context of two fundamental problems, which we intend to solve.1) Instability of AdS: The stability of Minkowski space and the stability of de Sitter space are celebrated theorems in mathematical general relativity. In contrast, the dynamics near Anti de Sitter (AdS) space, the maximally symmetric solution with negative cosmological constant, is mathematically entirely unexplored. Heuristic andnumerical arguments suggest instability of this spacetime. Instability problems are typically much more intricate than stability problems and require very different techniques. A rigorous proof of instability would resolve a major conjecture in general relativity and have important implications for theoretical physics.2) The Black Hole Stability Problem: A central problem of general relativity is to prove the full non-linear stability of the 2-parameter Kerr family of black holes. Very recently, the dynamics of linear waves on such stationary black holes has been satisfactorily understood. The proposal suggests to suitably enhance the techniques developed for linear scalar waves to be applicable in the non-linear, tensorial setting of of the Einstei
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Bridging Europe: A Quaternary Timescale For The Expansion And Evolution Of Humans' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Timing is everything in archaeology; EQuaTe will build on exciting advances in amino acid and thermoluminescence (TL) dating to provide a chronology that will deepen our understanding of early human evolution and migration throughout Europe.During the Quaternary (the last 2.6 million years), Europe witnessed major climatic oscillations, with periodic expansion of ice sheets into lowland areas, changes of sea-level, re-organization of plant and animal communities, and the evolution and migration of human populations. Despite extensive studies of the rich European geological and archaeological records (providing a detailed history of these environmental changes), these have little meaning without a secure chronology.  Dating is extremely difficult beyond the limit of radiocarbon dating (~60,000 years). Key to our approach is the discovery that commonly-occurring calcitic fossils (snail opercula) provide both closed-system repositories for amino acids and a stable TL signal over Quaternary timescales. It is therefore now possible to use both dating methods on the same biomineral to build a strong dating framework; taking advantage of momentum in this field, EQuATe will apply this approach on a European scale.This novel paired chronology, spanning the entire Palaeolithic in Eurasia, will refine our understanding of European human cultural and population dynamics and their relationship to environmental change over the last 2.6 Ma, across a region stretching from Britain to the Black Sea. EQuaTe will provide the scientific means to answer critical questions, e.g.: when did early human populations expand into Europe, and under what climatic conditions? Are apparent differences in tool technologies a reflection of different species, technical evolution over time, or geographica