RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Novel Organoselenium Catalysts for Green Chemistry'.

assistant: **Concept**

Organic Chemistry is mainly dealing with the synthesis of molecules. In order to be able to do this efficiently, one must have reasonable insight into the way in which bonds between atoms can be formed or broken and how molecules can react with each other. In our research proposal we make use of the special properties of an interesting class of molecules containing selenium atoms. The properties of these selenium-containing molecules are wide spread and we propose to investigate their use in different areas. In this proposal we describe the development of reactions using only catalytic amounts of these reagents. This means that one catalyst molecule will have the potential to create thousands of new molecules with special properties. The development of these new selenium reagents and their application in a certain type of reactions, the electrophilic addition reaction to carbon-carbon double bonds and oxygen-transfer reactions, form the main part of this proposal. The development of reaction sequences with these reagents as catalysts will be studied in much more detail and further optimisation of the selenium reagents are necessary for an efficient performance in the catalytic reactions. The use of 'green', peptide-based catalysts is a novel and special feature for selenium reagents. Applications of these methodologies to the synthesis of target structures are further points of interest and will be focussed upon towards the end of the project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Secure, safe, sustainable and affordable on-site generation of Hydrogen Peroxide' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Hydrogen peroxide (H2O2) is one of the world’s most widely used chemicals – it is a powerful oxidant and disinfectant utilized across water and wastewater treatment (WWT); pulp, paper and textile; medical, and electronics industries. It is highly effective against a wide range of pathogens, including SARS-CoV-2 (cause of COVID19), as well as in facilitating the breakdown of human-generated pollutants. While H2O2 itself is “green” – decomposing to pure water and oxygen – today’s supply chain is far from it. The global consumption of over 6.5M Tons is produced in centralized chemical plants, emitting greenhouse gasses (GHG) equivalent to the emissions of 3M cars, and outputting over 60M Tons / annum of toxic waste . Delivery from these centralized  plants to millions of distributed points of use requires transportation of a high-concentrate, highly-explosive solution, break-down to manageable units, and dilution from 30% - 70% solutions down to a few parts per million (ppm) - a complex, hazardous, costly, and increasingly regulated supply chain.This is also vulnerable supply chain - in the present COVID19 outbreak a shortage is already felt in the market.Our goal is to replace today’s GHG emission and toxic-waste intensive, hazardous, prone to supply interruptions, and costly H2O2 supply chain, with our PeroxyPro – the world’s first and only commercial technology solution for the on-site generation of hydrogen peroxide through direct electrochemical synthesis, using only water, electricity and air as inputs. PeroxyPro will secure consumable-free supply of a highly effective biocide and oxidizer in critical applications; will displace centralized, GHG and toxic-waste intensive production, with an eco-friendly, zero-emission and zero-waste, distributed generation process; a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Digital Personalized AI Based Platform Training Parents and Therapist to Develop Children with autism everyday Interaction' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

An intensive evidenced-based therapy in the early years of a child with autism determine the child's developmental trajectory. Children with autism don't get the therapy they need due to lack of qualified therapists and lack of training. SocialMind developed a platform that trains parents and therapists to turn every interaction into an evident-based opportunity. The company developed a protocol that is based on ESDM (Early Start Denver Model) and PRT (Pivotal Response Treatment) autism evidence-based intervention. SocialMind broke down these comprehensive interventions into a series of concrete parenting skills, that motivate the child to interact and learn throughout the day. An essential component of the solution is based on the ability of the parent to upload a video of themselves interacting with their child and get a response from our Hybrid-Response system:  AI software analyzes the audio and visuals, and then a member of our community of qualified reviewers (parents that are our mega users, and students) goes over and complements the machine assessment. The company has so far helped 150 children progress. In the uploaded video the company annotates child and parent behaviors and makes a ""basic behavior annotation"" that enables an accurate and efficient review and feedback, feedback is generated that is synchronized to the interaction, and sent back to the parent. A second machine analysis will be used on the  feedback to identify errors and alert the expert level before the feedback is sent back to the parent.Based on data collected from home interactions, the system will learn novel therapy insights from analyzing child development characteristic, parent implementation characteristics, and the best intervention skill that the parent should learn to optimize t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Collective excitations in finite fermi systems' to be submitted under Fourth Framework.

assistant: **Abstract**

Since several years the applicant is carrying on some research activity in collaboration with M.V.Andres on (see ref. 13, 14, 21, 24, 26 in the list of publications) a) Dynamical distortion effects in heavy ion collisions b) Multiphonon excitation in grazing heavy ion collisions. One of the scopes of the proposal is to pursue the collaboration on these subjects in a more efficient way and to enlarge it involving other people of the same Department in Sevilla who are already working on the same or related topics (Joaquin Gomez Camacho, Manuel Lozano, ...). A long term visit to Sevilla would also allow the establishment of a collaboration in the broad domain of the Interacting Boson Model (IBM) and its microscopic foundations. In this context, the work done by Jose Arias and Clara Alonso in Sevilla could be complemented by the experience of the applicant. The collective pair approximation (see ref. 1-5, 8, 10, 19, 27) and the mapping procedures (see ref. 20, 23, 25) more recently introduced by the applicant in the study of various many fermion systems, allow on one hand to exploit the simplifications introduced by the basic ideas of the IBM. On the other hand, they allow to take into account the underlying fermionic structure.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'A Chemogenetic Approach for the Treatment of Atrial Fibrillation' (Chem-Afib).

assistant: **Concept**

Atrial fibrillation (AF) is the most common sustained arrhythmia and is responsible for significant morbidity, mortality, and burden on the health care systems. Importantly, AF events may promote further fibrillatory episodes by inducing atrial remodelling. Traditional therapies for AF have relatively limited efficacy, and are either destructive (ablation), painful (defibrillation), or associated with side effects because of their global cardiac and systemic actions (drugs). Consequentially, novel treatment modalities for AF are direly needed. Here, we propose to develop a targeted, functional, non-destructive, and easily administered treatment for AF termination that does not cause pain or other side effects, which can also potentially prevent the associated atrial remodelling.Our proposed treatment is based on chemogenetics. This approach, which transformed neuroscience, utilizes inert drugs or designer molecules that have no effect on native host cells but can modulate the electrical properties of cells that are genetically modified to express specific chemogenetic receptors. Recently, we showed the feasibility of using chemogenetic tools for modulation of cardiac excitability. Here, we aim to evaluate the potential anti-arrhythmic capabilities of our newly created chemogenetic construct, which can cause transient electrical silencing in response to an inert drug. This approach has the potential to be the first chemogenetic tool capable of “defibrillating” cardiac tissue in a highly targeted manner. To evaluate the potential of this concept for treating AF, we plan to optimize its use and study its effects in an in vitro human cardiac tissue model of reentrant arrhythmias and in an in vivo AF rodent model.The suggested approach represents a paradigm shift in the way
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'A revolutionary cybersecurity SaaS helping small-medium business (SMEs) to protect their networks like large corporates do!' (SMEs), addressing dissemination and exploitation.

assistant: **Impact**

Incoming files present one of the most serious threats to every corporate network. Cyber attackers have the knowledge and resources to implement highly sophisticated attacks using various methods such as encrypted and distributed malware attacks, zero-day attacks and more. These are delivered via files which are introduced into the target network by various channels, including email, removable media, and web download. Malware attacks can create serious damage to the organization but current available defensive measures fail to provide any protection against such attack. The SMEs, accounting for over 95% of firms, require and demand special response to the vulnerability they have against cyberattacks.Yet, none of the existing solutions in the market, even less those based on military technology, is giving answer to them. ODIX 2.0 is the next generation of malware protection that is revolutionizing the way organizations protect their company from known and unknown threats. While other solutions focus on analysing user’s behaviour and statistical data to try and DETECT the undetectable, our game changing approach is to proactively PROTECT, sanitizing every file (keeping their full functionality) with our unique anti malware technology.After carrying out a feasibility study considering technical, practical, and financial aspects, we have successfully confirmedODIX’s viability as a significant business opportunity.Through SMEi-Phase 2 we plan to 1) Enrich our solution with innovative features and functionalities, evolving ODIX-2.0 fromTRL6 To TRL9; 2) pave the way towards its successful international market exploitation; 3) develop an operational strategyto grow our company based on the SME market, the power to easily and cost-effectively protect their files. Thus, in the ne
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Inter-university dissemination project of Omi' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

This project aims at the consolidation of some of the tasks initiated in the recently finished OMIDIS project and will drive a natural continuation of the Interuniversity activities related to OMI started there.The project will focus on: The operation and consolidation of the European Inter University Network (IUN) continuing with its former activity acting as a distribution centre of the OMI technologies and products inside the Academic Research Centres. An extension of the Inter University Network into the new markets of interest to the OMI Community as are: North and Central America, Far East Countries, East and North European Countries, and other areas of possible interest for the OMI dissemination activities. Reviewing, analysing and consolidating the existing OMI documents, more in particular the OMI Reference Book, to generate an easy-to-use tool for the institutions that could use and include in their research projects the existing OMI technology. Use of new technology dissemination channels as is the WWW on the INTERNET network to provide up-to-date information of IUN community, OMI technology consolidation and OMI related information events, and including the conventional training activities and concertation events too.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project '5G for Connected and Automated Road Mobility in the European UnioN' (5G-CARMEN), addressing dissemination and exploitation.

assistant: **Impact**

European mobility is drastically changing: growing urbanisation, environmental aspects, and safety are only a few of the key indicators pointing in this direction. Road infrastructures and vehicles are blending with the digital world, becoming always-connected, automated and intelligent, delivering optimal experience to passengers, and addressing societal goals (e.g., emission and accident reduction) and economic needs (e.g., vehicles as smart-living environments). In this respect, the European Union pushes for large-scale collaborative cross-border validation activities on cooperative, connected and automated mobility. 5G-CARMEN addresses these challenges harnessing the concept of “Mobility Corridors”. In 5G-CARMEN important European industries, academics and innovative SMEs commit to achieve world-wide impact by conducting extensive trials across an important corridor (by people/goods traffic volumes), from Bologna to Munich, spanning 600 km of roads, connecting three European regions (Bavaria, Tirol and Trentino/South-Tyrol) across three countries. Vehicle manoeuvre negotiation (at various levels of automation), infotainment, and emission control in sensitive areas are the cross-border use cases targeted by 5G-CARMEN pilots in order to maximise the project commercial, societal, end environmental impact.The project will build a 5G-enabled corridor to conduct cross-border trials and will deploy a mixture of 5G micro- and macro-cells for ubiquitous C-V2X connectivity. The 5G New Radio will be used to support latency sensitive and/or bandwidth hungry services and applications. The project will leverage on a distributed mobile edge cloud spanning from the vehicle itself to the centralised cloud. Multi-tenancy and neutral host concepts will be leveraged upon to deliver a f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Inferring DNA binding specificities through in silico folding of natively unstructured protein regions', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

A major challenge in post genome biology is the functional assignment of gene products. An important goal is the identification and characterization of DNA binding proteins – especially transcription factors – and of their specific target sequences. Recent strategies for determining protein-DNA binding specificities combine experimental high throughput data with bioinformatics algorithms providing encouraging results. Structure based approaches are particularly promising, as they can predict previously undetected binding sites and open the road to the rational design of novel regulatory molecules. This project aims at expanding our current knowledge of protein-DNA binding modes. We will use structural bioinformatics methods for predicting the structure and specificity of DNA binding proteins, focusing in particular on natively unfolded protein regions (flexible segments that do not assume a fixed conformation in the native state, but become ordered upon binding) which are frequently observed in DNA binding proteins. We will first develop a general method for predicting the atomic coordinates of the DNA bound conformation of these proteins combining fragment based methods for protein structure prediction and novel DNA-protein specific energy potentials. Predicted complexes will be subsequently used to predict DNA binding sites in genomes and the accuracy assessed on the basis of available experimental reference data. The results of this project will improve our understanding of the molecular details of protein-DNA interactions, assist the annotation of genomes, and prioritize experiments aimed at verifying the predicted specificities. On a more general level, this research will further advance knowledge in the field of macromolecular interactions, a central problem in sy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Wafer Scale Ultra-Clean Van der Waals Heterostructures' (2D-TRANSFER).

assistant: **Concept**

Two dimensional materials (2DM) and their van der Waals (vdW) heterostructures have opened new opportunities to developatomically thin electronic and optoelectronic devices with a wide range of functionalities. While thousands of research papersdemonstrate proof-of-concept studies with improved and novel performance using small-scale exfoliated crystals, a number ofchallenges still remains when these are attempted to be scaled up on wafer-scale with CVD grown 2DM. One of the key challenges isthe transfer process of 2DM from their growth substrate to another 2DM or a target substrate for intended use. Currently, this processis performed using organic polymers to support 2DM, which introduces considerable amount of contamination and mechanicaldamage to the transferred layers.We propose to circumvent the existing issues of the transfer process by employing a new technique recently invented in NGI, whichcompletely avoids use of organic compounds. This approach enables production of heterostructures with perfect interfaces free frominterlayer contamination and correspondingly excellent (opto)electronic behaviour. In addition, eliminating polymeric supportsallows new possibilities for vdW heterostructure fabrication: assembly at temperatures up to 600°C, and in different environmentsincluding ultra-high vacuum (UHV), liquid submersion and improved mechanical stability.This project will apply our novel approach for wafer-scale use, considering requirements of industrial companies, such as the choice of2DMs and wafers, quality standards, throughput and reliability. The improved inorganic transfer technology will be then licensed to aselected 2DM foundry. In addition, we will develop an instrument for wafer-scale 2DM transfer that employs our innovative approach,which will be ma
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'European Nicotinamide Diabetes Intervention Trial'.

assistant: **Objectives**

The overall objective is to establish in a prospective, randomized, placebo controlled trial whether daily oral administration of high dose nicotinamide can produce a clinically useful reduction in the rate of progression to IDDM in relatives at increased risk of contracting the disease. Specific aims are: 1.To complete recruitment to the expanded ENDIT trial and perform the 3 year interim statistical review. 2.To extend and strengthen the current multinational programme of screening for risk of IDDM in first degree relatives. 3.To develop and test new strategies for risk assessment within this population, including application of novel miniaturized high-throughput genetic and immune assay systems. 4. To establish an international collaborative network capable of undertaking a programme of prompt, high quality and cost-effective intervention trials in individuals at high risk of progression to IDDM.Nicotinamide, a soluble B group vitamin, has been known for many years to offer protection to pancreatic beta cells against a variety of toxic agents both in vivo and in vitro. Recent research has established a sound scientific rationale for its use in attempted prevention of human type 1 diabetes, and promising pilot studies have been performed. ENDIT, a five year trial of sustained release nicotinamide versus placebo as a potential means of delaying the onset of type 1 diabetes, is the first multinational diabetes prevention trial to get under way. Non-diabetic high risk first degree relatives have been randomized to treatment in 11 European countries, Canada and the USA, while 11 additional European countries are currently preparing to participate. A total of 201 local centres are involved. The aim over the past 3 years has been to set up the trial and to randomize 320 pat