RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Human Fungal Pathogens' in the context of a Fifth Framework call.

assistant: **Objectives**

Fungal infections are becoming a major medical problem. Life-threatening Candida, Coccidiodes, Cryptococcus, Histoplasma, and Aspergillus infections are on the increase. The most common fungal pathogen of humans, Candida albicans, causes superficial infections of mucosal epithelia, but also deep-seated infections, particular in immuno-compromised patients, which are often fatal. The increasing use of immunosuppressive therapy and the spread of AIDS has led to a steep increase in the incidence of fungal infections. Few effective and safe antifungal drugs are available and the frequency of drug-resistant fungal is increasing. Hence, new and effective antifungal drugs must be developed. The identification of new antifungal targets depends upon strong fundamental research programmes, which are the topics of this Conference Series.This application requests funding for the second and the third meetings in a Conference Series on Human Fungal Pathogens. In September, 1999, the first conference in this series will deal with Fungal Morphogenesis and the Cell Wall. The EC does not provide support this conference, but the conference takes place because of the contribution from the ESF and a significant amount of industrial sponsorship. This support reflects the great relevance and interest in the emerging fungal threat to human health, and we now seek appropriate funding from the EC to continue the Conference Series.The first of the two proposed conferences will address virulence factors which play central roles in fungal disease (fungal adhesion to host tissues, fungal enzymes which attack host tissue, and fungal cell shape). The second conference will focus on host-pathogen interactions (how the host responds to fungal invasion, how the fungal protects itself from host immune def
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Conformational Dynamics of Proteins by Solid-State NMR' (2007-2013) targeting Seventh Framework.

assistant: **Abstract**

Conformational dynamics are intimately linked to the biological activity of proteins, thereby regulating the essential processes of life. In particular protein motion plays an essential role in catalysis, allowing conformational rearrangements to align key catalytic amino acids and in ligand binding allowing the entry of co-factors into areas that would otherwise be inaccessible. Mobility also plays a major role in the thermodynamic stability of functional states; in molecular recognition processes that often involve disorder-to-order transitions; and in allostery and molecular signalling, where correlated molecular motions can transmit information between distant sites in a protein. Dynamic transitions also mediate the onset of pathological malfunction and disease. NMR spectroscopy is uniquely suited to study a large number of these dynamic processes, resolving detailed and important site-specific information about motions spanning a vast range of time scales in both folded and unfolded proteins, and in both the liquid and the solid phase. We believe that the key to understanding the complex relationship between protein dynamics and molecular function and malfunction requires an accurate description of the behavior of proteins in their different phases and forms, and an understanding of the transition between different states. In this study we are interested in developing a self-consistent framework for measuring and describing protein dynamics in the solid state. To this end in this project we propose to develop a number of NMR methods extending substantially the scope of accessible protein motions in solids. This work is a part of concerted collaborative effort that couples for the first time NMR data from both solid and solutions with complementary data from elastic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Production of functional innovative ingredients from paper and agro-food side-streams through sustainable and efficient tailor-made biotechnological processes for food, feed, pharma and cosmetics'.

assistant: **Concept**

Agro-food and Paper mill side streams and by-products are sources of unexploited organic fractions exploitable into safe microbial biomasses, functional ingredients and intermediates, e.g. prebiotics, pre-fermented ingredients, bioplastics and chemicals. The INGREEN bio-based ingredients/materials will be used to produce innovative functional products for food, feed, packaging, pharmaceutical, nutraceutical and cosmetic sectors. The INGREEN outcomes will be obtained by validated tailor made biotechnologies based on safe microorganisms or eco-friendly approaches. Logistics and storage conditions will be optimized to favor the flow from feedstock to the bio-based prototype producers. INGREEN aims to demonstrate in industrial environments the efficiency and sustainability of the target biotechnologies to produce i) lactobionic acid (LBA), galactooligosaccharides (GOS), microbial safe biomasses from whey; ii) polyhydrohyalkanoates (PHA) enriched biomasses and purified PHA, as prebiotics and bioplastics respectively, from paper mill wastewater; iii) functional pre-fermented ingredients from rye/wheat milling fractions. Safe and characterized INGREEN ingredients will be used for innovative functional cheeses, bakery products and nutritious feeds. Functional GOS, LBA and pre-fermented bran will be used to produce prebiotic immune-stimulating gel, nutraceutical supplement and cleanser for human health. INGREEN biodegradable material will be valorised into bag in box to boost INGREEN fluid prototype sustainability. Prototype safety, shelf-life, quality and functional performances will be compared to benchmarks. Also LCA/LCC, sound business cases and plans and compliance with REACH and any relevant EU safety legislation  will be applied over the whole project to assess prototype
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Spatial pattern formation in passive systems'.

assistant: **Innovation**

In many recent experiments the nonlinear response of the media irradiated with laser light cannot be explained by models in which the Maxwell equations were simplified using slow envelope, paraxial and scalar approximations. It is therefore important to extend the present theoretical models to reduce the gap between theory and experiments. This research will last two years and consist of two parts. In the first part pattern formation beyond the above mentioned approximations will be studied. The second part will be devoted to use pattern formation techniques in high-order harmonic generation for controlling the conversion efficiency enhancing some harmonic and depressing others, having harmonic emission not collinear with the generating fields and with laser intensity much higher than the saturation intensity. The theory of induced representation and the group theoretic interpretation of the Fourier Trasform should be very useful to derive analytical results and new numerical algorithms.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Endoscopic tissue time machine' (EPIC) targeting Horizon Europe.

assistant: **Abstract**

Head and neck cancers (HNC), which include malignancies of the oral cavity, tonsils, nasopharynx, and larynx, are life-threatening, particularly when diagnosed in advanced stages. Effective management requires early detection and continuous monitoring to enable earliest possible intervention of high-risk precancerous lesions. Unfortunately, current endoscopic techniques are limited in their ability to provide accurate predictions of disease trajectories.The overarching goal of EPIC is to develop a new endoscopic technology to predict HNC tissue state trajectory with the fidelity needed to intervene in the present – an “endoscopic tissue time machine”. We will create a miniaturized 2.0 mm forward-viewing fibre-optic probe compatible with head and neck (H&N) endoscopes that integrates Raman spectroscopy (for molecular state), optical coherence tomography (for morphological state), and real-time optical vascular imaging (for microvascular state). This ground-breaking label-free platform technology will facilitate a synergistic integration of clinically relevant multi-modal endoscopic data, bridging different scales and modalities while putting endoscopic data in a clinical and biological context. We will develop an explainable deep learning model (an endoscopic time machine) to predict transition points in the progression from normal tissue to dysplasia and ultimately to cancer in an animal model. To address the unmet clinical need, we will conduct a longitudinal human observational study utilizing the endoscopic tissue time machine for real-time in vivo prediction of progression risk from dysplasia to cancer.This project will integrate scientific and technological advances to offer new insights into the microenvironment of H&N carcinogenesis, enhance understanding of clin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Complexity Inside NP - A Computational Geometry Perspective' (CGinsideNP) targeting Horizon 2020.

assistant: **Abstract**

Traditional complexity theory focuses on the dichotomy between P and NP-hard problems. Lately, it has become increasingly clear that this misses a major part of the picture. Results by the PI and others offer glimpses on a fascinating structure hiding inside NP: new computational problems that seem to lie between polynomial and NP-hard have been identified; new conditional lower bounds for problems with large polynomial running times have been found; long-held beliefs on the difficulty of problems in P have been overturned. Computational geometry plays a major role in these developments, providing some of the main questions and concepts.We propose to explore this fascinating landscape inside NP from the perspective of computational geometry, guided by three complementary questions:(A) What can we say about the complexity of search problems derived fromexistence theorems in discrete geometry? These problems offer a new perspective on complexity classes previously studied in algorithmic game theory (PPAD, PLS, CLS). Preliminary work indicates that they have the potential to answer long-standing open questions on these classes.(B) Can we provide meaningful conditional lower bounds on geometric problems for which we have only algorithms with large polynomial running time? Prompted by a question raised by the PI and collaborators, such lower bounds were developed for the Frechet distance. Are similar results possible for problems not related to distance measures? If so, this could dramaticallyextend the traditional theory based on 3SUM-hardness to a much more diverse and nuanced picture.(C) Can we find subquadratic decision trees and faster algorithms for 3SUM-hard problems? After recent results by Pettie and Gronlund on 3SUM and by the PI and collaborators on the Frechet di
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Size Effects in Mechanical Properties' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

The aim of NANOMESO is to develop knowledge in nano-micromechanics and to develop a validated computational tool to understand and predict unique plasticity phenomena experimentally observed. In nanotechnology object scales are determined by optimised fun ctionality resulting in ever shrinking sample size dimensions to the sub-micron regime and decreasing structural length scales such as grain size to the nanometer regime. The experimentally observed size dependent plasticity is not explained by existing th eories. Since the mechanism occurring span multiple time and length scales, a multiscale computational approach is required where knowledge is transferred from ab-initio across atomistics to the mesoscale (sub-micron-scale). The atomistic pathways and ener getics of the deformation mechanism in confined systems with interface dominated structures will be determined and implemented in a dislocation dynamics code allowing simulation of mechanical behaviour in a one-to-one scale with experiment. The NANOMESO consortium involves leading-edge US and EU theoreticians and modellers that have already a great expertise in the field. The full integration of two leading experimental groups in nano-micromechanics into the project (with national financial support) and t he EU-project leader having an international reputation for both computational and experimental approaches in nano-micromechanics, guarantees maximum synergies between experiment and modelling. The performance-oriented objectives are advancing the front iers of knowledge in multifunctional materials science. NANOMESO will help to overcome the initial barrier that usually prohibits or decelerates the use of novel materials/components due to a lack in theory/understanding. NANOMESO will support long-term in novation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'MSCA FIRE: Fellows with Industrial Research Enhancement' to be submitted under Horizon 2020.

assistant: **Abstract**

MSCA FIRE: Fellows with Industrial Research EnhancementThe FIRE programme is an integrated 4 year Doctoral Training programme, bringing together two national Centres for Doctoral Training: the Centre for Sustainable Chemical Technologies and the Centre for Digital Entertainment. The objectives of MSCA FIRE are to increase the international aspects of these successful intersectoral and inter-disciplinary programmes and to develop the elements of transnational mobility and career development, common to our industry facing doctoral programmes.  Objectives are to:- Offer FIRE Fellows the benefits of two established national Doctoral Training Centres, as they expand their international company placement activities.-  Bring Fellows the benefits of the cross-sectoral reach of both Centre, with vibrant industries.-  Enhance interdisciplinarity and offer added-value training practices beyond their specialised research area, to all fellows.-  Use these synergies to fire-up the fellows to become autonomous, creative, highly-skilled and fully ready for careers in international industries.This will be achieved by:- Implementing a combined 4 year doctoral training programme,- using two existing national Doctoral Training Centres and their already engaged industrial partners.MSCA FIRE will deliver:-  20 autonomous, creative, highly-skilled scientists and engineers fully ready for careers in international industries, and -  A model for intersectoral, interdisciplinary doctoral training in an international environment.Industrial partners ensure that research carried out is relevant and will enhance employability of graduates, both in Europe and globally.


**Keywords:** interdisciplinary, intersectoral, international, doctoral training, industry partners, digital entertainment, sustaina
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Technologies for the configuration of the surface and for joining of parts of foamed aluminium'.

assistant: **Concept**

The project deals with working up of foamed aluminium for making marketable products for architecture and furnishing. Especially technologies for the configuration of the surface and for joining of foamed aluminium will be investigated, developed and optimised. General aims of the project are: - prettiness of products - reproducibility of properties of surfaces and joinings - economical efficient procedures - avoiding of ecological problems with procedures and products Important working fields (with respect to foamed aluminium) are: - cut" (saw, lathe, mill, erode) - mechanical surface treatment (grind, brush, sandblast, polish) - painting, varnish - chemical surface treatment (corrode, eloxadize) - soldering and welding - adhesive bonding (design, adhesives) - clamping, tucking - foamed in attachment elements "
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'An innovative high capacity Accordion bioreactor technology for high performance and low cost microalgae production' to be submitted under Horizon 2020.

assistant: **Abstract**

Access to vital raw ingredients for food/feed production is an increasing challenge in several industries. Biopharmia is a Norwegian company focusing on cultivation of microalgae through its development of a proprietary bioreactor. Through years of expertise and collaborations with experts in the field of microalgae growth, Biopharmia have developed and patented the Accordion bioreactor, a proven and efficient platform for industrial scale production of high quality microalgae, at lower energy and decreased production cost, compared to other solutions. This technology aims to strengthen Europe’s position in the microalgae market, which is currently weak due to cheaper, low quality foreign competitors. The technology describes the unique wave configuration comprising the frame work of the bioreactor, which contributes to higher productivity and lower cost of production and investment when compared to competing technologies. The modular design of this closed system greatly minimises the risk of contamination and can be easily adapted to large scale production. Biopharmia need to undertake the proposed innovation project to develop and further test the Accordion technology with multiple algae strains. The company has a close collaboration with the University of Arizona (UA) and has demonstrated the efficiency and productivity of its bioreactors through extensive testing at UA. Biopharmia has supplied biomass to a number of entities in Norway with very good results. Biopharmia has Letters of Intent about supply of biomass to two Norwegian customers in different segments, food supplements and aquaculture. In 2012 the company raised €1 million in private venture capital from IFE Venture. Biopharmia intends to establish initial production using the Accordion technology for the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Demonstration of LIDAR Based Wake Vortex Detection System Incorporating an Atmospheric Hazard Map'.

assistant: **Objectives**

Wake vortex and wind shear are major causes of accidents and injury to passenger and crew of all aircraft types. There has been little protection and the main way of mitigating accidents has been to have mandatory separation times that affect the operating performance of airports.  The objective of GREEN-WAKE is to develop and validate innovative technologies that will detect the Hazards and thus improve the operating efficiency of an airport and improve passenger safety.  GREEN-WAKE will represent a significant step beyond current state-of-the–art as it intends to improve upon: (1) The understanding of wake vortex and wind sheer detection. (2) Current detection methods. Commercially available technologies do not provide a solution and this project seeks to develop a new sensor that is able to provide real-time detection. It will develop new and novel technologies particularly in scanning and detectors that will enable real improvements to be made. Further it will develop a new concept in the 3D visualisation of atmospheric hazards, which is an important first step to developing closed loop-systems.  GREEN-WAKE will improve the knowledge and functionality of previous projects.  GREEN-Wake meets and will contribute to four objectives of the AAT.2007 call. Many of the concepts and the innovations will have applications in other on-board sensors for monitoring atmospheric hazards, engine emissions, engine heath and air quality.  The 3D simulator will take another new step, creating tools that can model instrument performance.    The structure of GREEN-WAKE will enable the latest technologies to be individually evaluated and made available to industrial users. Given the high level of innovation that goes beyond just the sensor, this is an important aspect to the exploitatio