RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Unveiling transient material synthesis in dilute solutions and their solid morphology combining dDNP and MAS-DNP.' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The silicate speciation process is of large scientific and industrial interest because determines the morphology and reactivity of the silica products and biological control of the silica morphology has generated an interest for novel mechanisms for biomimetic silica synthesis. These processes occur typically in very dilute solutions (in the mM range) and no general approach is currently used to report on both the liquid-state speciation and the solid-state atomic-level morphological characterization during the speciation process. As a result, an important gap in the current understanding needs to be addressed.Here we propose to combine cutting edge dynamic nuclear polarization (DNP) in its two main branches, dissolution DNP and MAS-DNP, to investigate the silicon-based materials formation process. The project is original and of high impact and can currently be performed only at the host institution. Dissolution-DNP and MAS-DNP experiments will be used to elucidate the speciation in dilute solutions and the structural morphology at different stages during the oligomeric formation process of silicon-based materials. In this way, a complete information can be obtained. The immediate result can be envisaged either in an important expansion of the host group research activities into dissolution DNP, and the applicant acquisition of important and strategic skills in chemistry, spin physics, DNP and solid-state NMR. The medium-term goal during the course of this action is to apply the techniques to a broader range of silicon-based materials, and the applicant acquisition and implementation of new organizational and managerial skills.


**Keywords:** nuclear magnetic resonance, hyperpolarization, dynamic nuclear polarization, dissolution dynamic nuclear polarization, magic ang
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Assessment and improvement of selected technologies to remove or inactivate TSE - causing agents (prions")"' (1994-1998).

assistant: **Innovation**

TSE causing agents (prions") are extremely difficult to remove or inactivat especially if the biological activity of the matrix (e.g. enzymes, antibodies, plasma or othel biologically derived therapeuticals) must be retained. Nevertheless, some processes havE developed and shown to inactivate prions with high efficacy (e.g. the HAEMOSAFE proce others show potential to remove prions (e.g. reversed phase chromatography, hydrophot interaction chromatography, solvent extraction), but there exist contradictory results in lite as to what dearee. This project will determine the potential of these processes in 2 stages: a) they will be optimised for a number of key biologicals to yield unchanged biologic active products in high yield and purity b) the prion removal or inactivation will be demonstrated in spiking experiments. Thf be both IN VIVO and IN VITRO tests done in parallel in order to evaluate the pc of the newly emerging in vitro tests (DELFIA, western blot). "
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Semantic Interoperability and Data Mining in Biomedicine' (SEMANTICMINING) targeting Sixth Framework.

assistant: **Abstract**

The aim of this proposal for a Network of Excellence entitled Semantic Interoperability and Data Mining in Biomedicine is to establish Europe as the international scientific leader in medical and biomedical informatics. The long-term goal of the network will be the development of generic methods and tools supporting the critical tasks of the field; data mining, knowledge discovery, knowledge representation, abstraction and indexing of information, semantic-based information retrieval in a complex and high-dimensional information space, and knowledge-based adaptive systems for provision of decision support for dissemination of evidence based medicine. The proposal is a response to the strategic objectives addressed in the IST call 1, areas 'Semantic-based Knowledge Systems' and 'eHealth'.The general objective of the network is to bridge gaps in the European research infrastructure and to facilitate cross-fertilisation between scientific disciplines. Traditionally academic departments in the domain have their roots either in computer science, system engineering (including a variety of engineering disciplines) or in a medical or clinical context. The proposed network is composed of partners from these scientific areas, all bringing their experience and in-depths knowledge together into a common framework. An important aspect of this is the merging of medical or clinical informatics and bioinformatics including the new fields of genomics and proteomics. Another bridging activity addressed by the proposal is knowledge-transfer and co-operation between academia and organisations in the health and welfare sector, such as standardisation bodies and public and user-driven health care organisations.The NoE application is based on the partnership of 25 participants from 11 Europea
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Local Diversity and Long-Run Development' (LODALORD) under Horizon 2020.

assistant: **Objectives**

Social scientists have long studied the effects of population diversity on society. The research project proposed here breaks new ground in multiple dimensions by rigorously estimating the long-run effects of (i) local population diversity, (ii) individual diversity, and (iii) the interaction between these two concepts, on comparative socioeconomic performance across locations and lineages within a country.Through a combination of two extensive high-quality databases covering the complete genealogy of more than five million individuals living in Quebec, spanning its settlement in the 16th century up to present day, as well an immense database covering more than 43 million worldwide individuals, I will analyze the effects of diversity using measures of diversity that are well-established in the field of quantitative genetics. The project will deliver the first within-country long-run investigations involving local and individual diversity.First, I hypothesize that the diversity of an individual’s ancestors has a significant effect on the productivity of that individual as well as his descendants. In particular, I hypothesize that individuals from more diverse lineages were more capable of adjusting to changing economic conditions, finding new productive niches, and thus raising that individual’s income.Second, I hypothesize that the negative effects of diversity found on the country level are less operative within a country. Thus, I expect to find that local population diversity has had a monotonically positive effect on long-run development within a country.Third, I hypothesize that there is an interaction effect between population-level and individual-level diversity. Thus, I suggest that the effect of individual diversity is affected by the diversity of the locality i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Intelligent Processing for Smart Composites'.

assistant: **Innovation**

Current industrial practice related to the processing of thermoset based composite materials involves the establishment of acceptable process conditions by trial and error. At present a satisfactory method for continuously monitoring the state of cure of the resins within the composite matrix does not exist.The aim of this research is to develop the technology which will enable the process conditions for autoclave and press moulding of fibre composite components to be established in real time from within the body of the composite component. The technology will be based on sensors embedded in the structure so as to be able to sense the internal conditions during the curing process.The major research thrust involved in the development of this technology include:Developing sensors which can be embedded in the composite to enable the state of cure and other process variables to be measured internally at critical points. Sensor development will be based on optical fibre technology and acoustic impedance will give the capability to monitor, amongst other parameters, temperature pressure and chemical changes.Developing practical means of embedding sensors and of making rugged connections to embedded sensors.Investigating the effect of various arrays of embedded sensors on the mechanical properties of composites.Fabricating demonstration components using embedded sensors to control process conditions.The technology developed in this project is expected to have wide applicability over a range of industrial sectors using composite materials. Benefits will include quicker and cheaper optimization of process conditions at the product development and prototype stage, improved control over process parameters leading to higher levels of consistency of product, reduced wastage and proc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Global and local star formation with state-of-the-art physics' to be submitted under Horizon 2020.

assistant: **Abstract**

New stars form within large turbulent complexes harboring several thousands of solar masses of cold gas: the molecular clouds. The diffuse gas collapses gravitationally and heats up via compression until nuclear fusion reactions ignite and the star comes to life. The full description involves an intricate interplay between large-scale environmental factors and small-scale processes close to the star, connecting a number of physical mechanisms, including magnetic fields, self-gravity, radiative transfer, and time dependent chemistry.The aim of the project is to construct a unified description of star formation, from large to small scales, using the world's most advanced numerical physics. A two-way approach will be used: the global approach (I) will deal with the dynamics of interstellar gas on the turbulent cloud scale, while the local approach (II) will concentrate on the formation of the protostellar seed.The objectives are:-  Ia. Carry out a parameter study of the effects of cloud mass, turbulence, radiative transfer, and magnetization on stellar populations in giant molecular clouds-  Ib. Create a realistic model for protostellar radiative and outflow feedback and examine its effects on the star formation efficiency-  Ic. Quantify the effects of supernova-triggered star formation- IIa. Simulate the formation of single protostars using extremely detailed physics (non-ideal MHD, multi-frequency radiative transfer)- IIb. Incorporate for the first time into the simulations a chemistry module which interacts with the gas and radiation field- IIc. Study episodic accretion events in protostars to try and explain under-luminous young stellar objects.This is an ambitious, strongly multidisciplinary program, which fits perfecty in the research activities of the host institute
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'On demand design of reversible shape changing metamaterials'.

assistant: **Concept**

We propose to commercialize a software for the automatic design of responsive metamaterials structures for additive manufacturing. During the course of the ERC AdG SIZEFFECTS project, the PI studied the effect of disorder on the mechanics of materials using discrete elements models (DEM), allowing for an efficient simulation of large disordered structures, including metamaterials. The METADESIGN project exploits DEM methodologies and optimization algorithms developed throughout the SIZEFFECTS project to solve the general problem of efficient and automatic design of responsive metamaterials machines. The algorithms put forward by the METADESIGN project is able to produce generic elementary metamaterial actuators with a broad set of possible movements and efficiencies. We propose a commercialization strategy that aims at deploying the software on the cloud allowing for flexible on demand services. Industrial partners and target costumers will be searched in the automotive, robotics and manufacturing industries.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Development of new hard decorative coatings based on transition metal oxynitrides' (HARDECOAT).

assistant: **Innovation**

The project aims at the development of new functional coatings for decorative and micro-optoelectronics applications. The coatings based on transition metals oxynitrides will be deposited by Physical Vapour Deposition techniques. The idea is to combine the excellent mechanical properties of the nitrides with specific optical characteristics (colours) of the oxides. By tuning the deposition conditions, one can obtain coatings with compositions varying from oxides to nitrides, thus exploring the vast spectrum of their optical and mechanical properties. The main technical deliverable will be a clean coating deposition process that is cost-competitive as compared to traditional electroplating methods. The use of plasma-based technology is resource efficient and reduces the environmental impact, resulting in the greening" of industry. During this project, new materials will be elaborated, characterised and their applications will be tested on an industrial scale. The oxynitride coatings will meet consumer demands because of their safety and extended lifetime. The project contributes to the development of knowledge about a novel class of materials. A better understanding of the fundamental properties of transition metal oxynitrides will be required to get insight i nto material's functionality. The consortium of 12 partners (6 research institutes and 6 industrial partners) from 5 European countries will bring together the critical mass of resources and competencies for this project. The role of the industrial partner s is to approve and implement the main project deliverables. The following widespread technology transfer aims at reinforcing the leading position of Europe in the decorative market and to improve its global competitiveness. The expected substitution of de corati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Next generation European digital passport with biometric data for secure and convenient boarder passage' (2002-2006), addressing dissemination and exploitation.

assistant: **Impact**

Boarder passage follows in many respects the same patterns as it did a few hundred years ago. The introduction of European digital passport will make a fully automated, secure and convenient walk-through boarder passage possible, thus establishing a completely new pattern in international travel.In order to fully realise their potential for improvement of security, convenience and efficiency, the implementation of European digital passports must be supported by an industrial initiative that shows the way to consistently apply standards, develop a range of techniques and connect to new border control and airport processes. The Digital Passport project will produce a new generation of digital passports based on the combination of a traditional booklet with large capacity IC micro-controller containing and processing cardholder's personal and biometric data. An RSA microprocessor will provide the support for PKI based security and capacity for encryption and digital signature. The terminal will support biometry, contactless connection to the passport and connection to applications including models of airport processes. The solution will be fully inside relevant standards such as ISO 7816-15, ISO 14443, ISO WG3 and it will collaborate with Schengen Information System and ICAO specifications.The system will provide a complete, robust, reliable, proven, non-proprietary, standards compliant industrial concept. It will speed up the consistent implementation of next generation European digital passport and prolong the expected life-length of early implementations. The results will be efficiently disseminated to governments, police and boarder control authorities, standardisation bodies, secure printer suppliers and all other interested parties. The proposed project closely follo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Genetical genomics of type 2 diabetes and cardiovascular phenotypes in experimental systems', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The objectives of this proposal are to establish causal relationships between altered gene expression regulation and diabetes metabolic changes in a rat model of spontaneous insulin resistance, the Goto-Kakizaki (GK) strain, and define disease-associated biomarkers. This multidisciplinary research addresses fundamental questions concerning the impact of naturally-occurring genetic variants on metabolic regulations contributing to diabetes and obesity, which have become dominant causes of reduced life expectancy in westernized societies. The proposed research builds on knowledge of genetic loci linked to variables relevant to insulin resistance and quantitative changes in metabolites derived by metabonomics, as well as advances in functional genomic technologies and expanding rat genomic resources (genome sequence, single nucleotide polymorphism - SNP). This research takes advantage of the availability of congenic strains of the GK rat, which are powerful tools for validating results from genetic and genetical genomic experiments and testing hypotheses regarding the involvement of SNPs in disease features. In this programme gene transcription profiling, bioinformatic tools and metabolic and biochemical studies will be applied in existing congenic strains of the GK rat carrying chromosomal regions of a locus associated with insulin resistance, transferred onto the genetic background of a control strain. Gene pathways and networks associated with altered metabolic variables will be correlated with SNP-derived haplotypes of the parental strains across the congenic intervals in order to fine map the causative genetic variant(s). This strategy, which integrates different mechanistic levels of gene expression (transcriptome and metabonome), will define biomarkers associated wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Incorporation of multiscale tissue-specific properties into musculoskeletal finite element modelling' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Despite the remarkable advances in musculoskeletal biomechanics during the last decade, realistic physiological tissue-level strain fields in whole bones are not yet known as these cannot be measured experimentally and the numerical simulations targeting this aim either do not include  microstructural and elastic information or investigate a sub-volume with simplified loading. However, this knowledge would be essential for unravelling the relation of micro-structure and function, and for understanding the rules dictating process of mechanosensation for bone remodelling and healing.The aims of this project are to (I) assess the realistic physiological mechanical environment in cortical bone tissue with previously unmatched accuracy to understand the functional adaptation of the intact microstructure and (II)  use this knowledge to investigate the variations observed in altered conditions, e.g. fracture healing.These goals will be achieved using and unprecedented combination of tools and data of an ovine lower limb model available at the research groups and  European collaborators of the host. In Phase 1, organ-scale homogenized finite element (FE) models will be developed which include tissue-specific, experimentally assessed anisotropic micro-elastic properties via a multi-scale homogenization approach and physiologically relevant loading histories from musculoskeletal models to compute macro-scale strain and stress fields. In Phase 2, these local macro-scale stresses will be applied on micro-FE models of experimentally assessed meso-scale tissue volumes to compute the micro-scale strains and stresses. In Phase 3 the developed approaches will be incorporated into a numerical framework suitable for the investigation of altered conditions, e.g. fractures. This will be app