RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'DIstributed generation in the associated States - Research priorites and challenges on the open electricity market'.

assistant: **Innovation**

Bulgaria and Romania, countries under accession to the EU, should focus their efforts on further implementing and refining their distributed generation energy policy, as one of the issues to full and prompt implementation of EU requirements, particularly with regard to the internal energy market. In order to reach these targets, these countries should promote further use of RES, align with energy requirements, and develop a pro-active policy in a liberalised electricity market, as mentioned in the document Communication from the Commission to the Council and the European Parliament - Roadmaps for Bulgaria and Romania".As distributed generation (DG) is foreseen to play during the next years an increasing role in the European electricity infrastructure and market, its perspective depends on local market conditions and regulations. Thus, there is a strong need to assess the barriers - technological, financial, and regulatory - which have to be removed, and to plan the actions for harmonisation of the related regulatory frameworks and market conditions. This assessment should be accompanied by targeted analyses of the private, public and political commitments, as well as of the impact of DG on key socio-economic aspects, CO2 reduction targets, emissions trading schemes, etc. In this respect, the developments of the DG technologies have to be analysed and encouraged under the specific circumstances facing these countries.The project's goal is to identify the main research priorities related to the distributed generation field and to analyse the regulatory implications for establishing the appropriate frameworks. Another key activity is the promotion and dissemination of the concepts and best practices on DG to key actors in the field. The results of the project can contribut
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Diagnostic drug response-profiling using SLAMseq' in the context of a Horizon 2020 call.

assistant: **Objectives**

One of the greatest challenges today is to select the right drug for the right patient at the right time. A lack of diagnostic tools for predicting therapy response currently hampers patient-tailored treatment decisions in the clinic with severe implications for economy and – most importantly – patient survival. Profiling transcriptional responses to drug treatment is a key method for probing the activity of targeted therapeutics and guiding their use in the clinic. A major limitation of established gene expression profiling techniques (such as microarrays and RNA-seq) is their limited time resolution precluding the distinction of direct from secondary transcriptional responses to drug therapy. This hampers their utility for deciphering drug action and guiding patient-tailored treatment decisions. To overcome this problem, as part of an ERC-StG project (Systematic in-vivo analysis of chromatin-associated targets in leukemia, 336860) I have co-developed thiol(SH)-linked alkylation for the metabolic sequencing of RNA (SLAMseq) as a rapid, robust and highly scalable method for the unbiased quantification of changes in mRNA production upon cell perturbations. Its unique features (low input cell numbers, short treatment-to-sample time, 1-day protocol library preparation in 96-well format) may qualify SLAMseq as the first method to probe the function, efficacy and selectivity of candidate therapeutics in primary (tumor) cells with unprecedented precision and on a large scale. In this ERC-PoC project, I propose to establish technical and commercial proof-of-concept for SLAMseq’s application in preclinical and clinical drug development and optimization, and for patient-tailored treatment selection. Upon the successful proof-of-concept for SLAMseq’s application as diagnostic too
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'What is controlling plate motions over the minutes to decades timescale?'.

assistant: **Objectives**

Tectonic ground observations from Global Navigation Satellite Systems (GNSS) increasingly show that plate motions are non-steady. In some instances, these non-steady motions have been suspected as precursory motions to large earthquakes.  However, the full spectral behaviour of transient plate motions, across minutes to decades, and kilometres to continental distances, is not well understood.  Here, I propose a multi-pronged approach to study how faults and plates worldwide are moving in response to the geodynamical (interior) and geophysical fluid loading/tidal (exterior) boundary conditions. The major questions to address are:  How transient is tectonic deformation over the minutes to decades timescale? What are the physical processes controlling the transient plate motions? To what extent are transient plate motions indicative of earthquake imminence? We will reveal the extent of non-linear tectonic motions by developing GNSS processing algorithms and applying these to data from the thousands of tectonic GNSS stations worldwide. With machine learning, numerical modelling, and laboratory experimentation, we will determine to what extent faults are modulated by variable regional tectonics and loading.  We will develop kinematic and laboratory modelling strategies to better understand transient tectonic boundary conditions such as transient slab-pull at subduction zones. While analysis will span continental and global scales, we will also investigate the kinematics of faults and fault networks with dense GNSS observations at a higher resolution, using GNSS and seismic data from north-central Chile as well as from laboratory-scale analog modelling to track fault failure in unprecedented detail. In Greece, a world-class example of a seismically hazardous zone of fault-net
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Renewable Energy for self-sustAinable island CommuniTies'.

assistant: **Objectives**

REACT will demonstrate the potential of large-scale deployment of RES and storage assets on geographical islands to bring economic benefits, contribute to the decarbonisation of local energy systems, reduce greenhouse gas emissions (GHG) and improve air quality.To do so, REACT will deliver a scalable and adaptable cloud-based ICT platform for RES and storage enabled infrastructures, supporting a holistic cooperative energy management strategy at the community level.  REACT will combine an optimal control of community owned energy assets, both conventional and renewable, with cooperative demand response (DR) actions, both explicit and implicit, to maximally exploit the flexibility of energy demand. To achieve this, REACT will leverage on energy production and consumption modelling, grid operation fault detection and diagnostics, multi-carrier supply optimization and optimal energy dispatching, while enabling synergies between different energy networks and micro-grids of island. REACT will deliver effective business models making a synergy of grid- and community-centric approaches for sustainable RES solutions, increased renewable energy exploitation, integrated and digitalised smart grids, and DR programs. Moreover, REACT will provide a solution that is fully compliant with contemporary regulatory and legal aspects, while respecting the data security and applying suitable data protection measures. REACT will target to enhance the overall energy security of geographical island with an inherent possibility for scale-up and deliver at least 10% energy savings, energy costs savings and GHG emission reduction both by 60%, and at least 50% increase in RES generation and similar reduction in fossil fuel consumption. REACT solution will be validated in 3 demo islands, while repl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Exploring the impacts of collaborative workspaces in rural and peripheral areas in the EU'.

assistant: **Concept**

CORAL aims to unpack the latent dynamics and impacts of collaborative workspaces (CWS) in rural and peripheral areas and integrate them as development tools in local and regional policies to open up new potentials for socio-economic development. Whereas we have observed the rapid rise of CWS in urban agglomerations the past 15 years, there is now a gradual rise of CWS in rural and peripheral areas too. However, there is no clear evidence about their functions, impacts and the ways that policymaking should promote the rural CWS wave and assist in linking the development of CWS with processes of local socio-economic development. In fact, that policy link is much needed for those disadvantaged places (places that don’t matter) , as only a few EU policies (e.g. Interreg) have assisted, in a fragmented way, the development of CWS in peripheral and rural areas. At the same time, there is an urgent need for qualified professionals in academia and the policy arena, in order to effectively promote CWS in the lagging parts of the EU and by that, open up new development futures. CORAL envisages to provide specialized and tailor-made training to 15 young researchers to better understand and support the development processes of CWS in rural and peripheral areas, their wider impacts at the local and regional level, as well as at the level of the individual worker and the enterprise. Moreover, through different means of dissemination and exploitation (knowledge exchange days, CORAL schools, digital platform), the impacts of CORAL aim to reach a wider audience ranging from public policymakers to private stakeholders and CWS communities across the EU. The CORAL consortium consists of nine beneficiaries (five academic and four non-academic) and 6 partner organisations (four academic and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'A Social History of Red Internationalism in post-1967 Arab world' (SoHRI67), addressing dissemination and exploitation.

assistant: **Impact**

SoHRI67 retrieves the unexplored social history of Red Internationalism (i.e.: internationalism informed by Marxism-Leninism and Third-Worldism) in the Arab Region during the long-1960s. It approaches internationalism as both ideological framing for action and militant political practice, to explore the transformative power of the new normative commitment to socialism and anti-imperialism matured by a new generation of Arab radicals in the wake of the Arab defeat of the 1967 war against Israel (the so-called Naksa). It focuses on the inter-Arab dimension of internationalism, to overcome – in the words of Bardawil – «the colonial divide assigning the Global South as locus of “concrete facts” and the North the manufacturer of “abstract theory», and re-cognize the South as site of original militant theorization. It specifically centers on the Lebanese-Gulf trajectory, to challenge the canonical historiographical representation of the Naksa as the inexorable end of the Arab revolutionary hopes unleashed by independence and decolonization, and retrieve, instead, its underexplored generative impact on the grammars, practices, and agendas of emancipatory political action. It adopts the vantage point of social history to move away from de-materialized, diffusionist, top-down approaches to the study of political theory and practice and relocate the latter’s genealogies, developments, and articulations in the lived experiences, contingent urgencies, and aspirations of the people who elaborated and embodied it. In so doing, it breaks new ground to: a) expand the knowledge of the Arab secular radical political traditions, b) further scale up the historical rethinking of the Naksa; c) further enlarge the understanding and recognition of the role of subaltern actors as agents of chan
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Alternative Splicing as a Driver of AMPAR Structural and Functional Diversity'.

assistant: **Objectives**

AMPA-type glutamate receptors (AMPARs) mediate fast excitatory neurotransmission in the central nervous system and are key regulators of synaptic plasticity, learning, and memory. AMPARs are tetrameric receptors assembled from GluA1–4 subunits, whose molecular diversity is shaped by alternative splicing, RNA editing, and association with auxiliary proteins. The flip/flop isoforms of generated through alternative splicing and the mRNA editing significantly affect receptor kinetics, trafficking, and pharmacology. However, how these isoforms influence the structure and function of native AMPAR complexes remains poorly understood.This project aims to uncover how developmental isoform switching of AMPAR subunits shapes receptor structure and function, using cerebellar granule cells (CGCs) as a biological reference. CGCs are the most abundant neuronal type in the central nervous system and express a restricted set of AMPAR subunits—primarily GluA2 and GluA4—with developmentally regulated flip/flop isoform expression and associate mainly with TARP γ2 auxiliary proteins. These characteristics offer a simplified and physiologically relevant model to study defined AMPAR assemblies.We will combine transcriptomic profiling (RNA-seq) to characterize the developmental dynamics of flip/flop isoforms in CGCs; structural biology (cryo-EM) to resolve AMPAR A2/A4 receptor assemblies mimicking those found in CGCs; and electrophysiology (patch clamp) to examine the impact of isoform composition on receptor function.This integrative approach will shed light on how alternative splicing modulates AMPAR structure and activity in developmentally relevant contexts. The findings will enhance our understanding of receptor diversity in the brain and may support the rational design of isoform-selecti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'BUILD UP Skills to Business'.

assistant: **Concept**

This project is directed towards establishing and upgrading large-scale qualification and training schemes in the Netherlands for craftsmen and other on-site workers, in the continuation of the BUILD Up Skills Initiative. The proposed project uses the results of the IEE-projects  and is a necessary step towards closing the gap between existing and needed skills for craftsmen and building workers in the Netherlands in the respect of meeting the 2020 energy objectives.The main objective of the project is to develop and pilot missing training materials on EQF-levels 2 - 4 based on the future-ready qualification schemes developed in BUILD UP Skills Pillar II. Secondary objective is to construct short skill measurement tests which enables the prevention of mistakes made by unconsciously incompetent workers, the detection of skills gaps and supply of industry relevant upskilling advice to craftsmen and building workers.Tertiary objective is to organise regional pilots in which we focus on implementation and evaluation of the developed materials and regional capacity building. We will support regional training partnerships with train-the-trainer sessions, regional labour market intelligence and implementing the developed trainings and assessments in practice in regional building and/or renovation projects. As results of the project the following will be achieved:• Increase the skills of 3000 craftsmen by the end of year 2018• Increase in RES-production of 11 GWh/year• Decrease of energy consumption of 69 GWh/year (EE)• Increase the employability of the building workforce with 3000 of which at least 5% women• Increase in investments in innovative sustainable energy technologies with €42.7 million• Acquired additional funding of €1.000.000,- to sustain the action
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'A precise irrigation monitoring system to provide an accurate measurement of water status in crops' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

There is an increasing global pressure on water resources and ensuring there is a sufficient supply in the face of climate change. This is of particular prevalence within the agriculture industry where irrigation is becoming increasingly important. Farmers typically overwater plants by 20% due to insufficient knowledge of plant water status resulting in significant wastewater and lowering plant yields. Saturas have developed StemSense, a unique sensor device that measures Stem Water Potential (SWP). SWP is scientifically proven to provide the most accurate data on plant water status. Saturas’ system then interprets this data, incorporating external factors such as meteorological data and provides recommended levels of irrigation to farmers. Farmers using the StemSense sensor experience up to 20% higher income, significant water savings and reduced costs. The overall objectives of the Phase 2 project are to design and engineer a miniaturised sensor that can be deployed in a wide variety of plants; to optimise the communication system and user interface; to scale-up production of StemSense with a contract manufacturer; and to demonstrate and validate the technology in in-field trials with farmers across Europe. The overall objective is to reach full commercialisation of StemSense as a reliable innovation validated by the relevant end-users, farmers.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Very long Baseline Interferometric astrometry of SiO masers around AGB stars to track the mass loss processes'.

assistant: **Innovation**

The Observatorio Astronómico Nacional (OAN) is building a new 40 meter state of the art VLBI antenna, at Yebes, Spain. We will use my experience to integrate this into the European astronomical networks. We will then use its innovative optical system to develop the new calibration method of "astrometric frequency phase transfer for spectral line VLBI'' for the general astronomical community. We will use this method to align SiO maser multi-transition observations to a common reference frame, and confirm the offsets between the emission sites at different frequencies. In parallel we will use the Yebes antenna as a single dish to confirm that the maximum flux for the multi-transitions occur at the same time. Once we have the confirmation of emission stimulation occurring at the same time in different places we have shown that the maser stimulation is radiative, solving the long standing conflict in this field. Once the correct model is known the astronomical community can trace the mass loss processes of evolved stars. This project therefore: uses my experience to assist the European Research Area, begins a long term collaborative project by developing new techniques, and provides me with the training and the experience to return to Australia.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Synaptic efficacies of single excitatory and inhibitory inputs to cerebellarpurkinje cells' (1994-1998).

assistant: **Innovation**

The Purkinje cell (PC), central to the cerebellar cortical network, integrates excitatory and inhibitory synaptic inputs to generate the sole output of the cerebellar cortex. It receives two excitatory inputs: a single climbing fibre (cf) making multiple contacts on the dendritic tree, and approximately 200,000 parallel fibres (pf), the axons of granule cells, each of which make only one or two contacts. The cf generates an all-or-none discharge of the PC, while summation of many pf inputs appears necessary to generate a single spike. The excitability of the PC is regulated by inhibitory interneurons in the molecular layer. The contribution of individual neurons to the critical balance of excitation and inhibition remains unknown. I will record from pairs of synaptically connected neurons to determine the synaptic efficacy of pf and interneuron contacts, how these efficacies arise, and how excitatory and inhibitory inputs interact to generate the output of the PC.