RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'When enzymes join forces: unmasking a mitochondrial biosynthetic engine' (MetaQ) targeting Horizon Europe.

assistant: **Abstract**

Enzymes have been classically investigated as standalone catalysts operating in a relatively diluted milieu. However, the cell micro-compartments are highly crowded environments and biological catalysis cannot be fully understood on the bases of simple diffusive models. We are tackling this challenge by reconstituting a full-scale biosynthetic pathway where multiple enzymes coordinate within a metabolon - a structurally defined setting that allows the vectorial transfer of substrates and products.Our system for exploration is the fascinating biosynthesis of coenzyme Q, an essential redox mediator for many pathways. The juxtaposition between its highly polar head group and hydrophobic tail renders this compound a challenging feat to handle. To synthesise its highly substituted aromatic head group, nature has amassed a large soluble supra-molecular complex consisting of no less than eight functionally distinct proteins that adheres to the inner-mitochondrial membrane. This infrastructure can extract the substrate whilst providing a shielded, hydrophobic environment for molecular transit.We will systematically characterize the functional, structural and evolutionary aspects of the involved protein machineries in interplay with the membrane. Our approach starts by exploiting ancestral sequence reconstruction to generate proteins of enhanced stability. We will build the metabolon in vitro to assess how the enzymatic activities are coupled in the context of a metabolon. Structural studies will reveal how the active sites are spatially organized with respect to the order of the enzymatic steps and substrate trafficking.  Our integrated strategy will unveil the pivotal evolutionary transitions that create a biosynthetic machinery. This research will go beyond classical enzymolo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Concurrent constraint programming for time-critical applications' under Fourth Framework.

assistant: **Concept**

The objective of this working group is to investigate time-critical applications within the paradigm of concurrent logic and constraint languages. More specifically, the group focuses on the design and development of a declarative logic language based on extensions of concurrent constraint programming. These extensions will consist of the introduction of real-time control structures and constraint domains for temporal reasoning. The design decisions will be driven by a set of specific applications. The group is also developing techniques for verification and analysis of programs, extending existing methodologies to logic languages.Many applications such as, robotics, network management, or deductive temporal databases have time-critical aspects. Until now programming concepts related to time have been mainly developed in the context of imperative programming. In contrast a declarative programming style, since it reduces the gap between specifications and programs, facilitates the development, maintenance and modification of such programs. Declarative programming is supported by both functional and logic languages. Logic languages also have the advantage that they allow simple concurrent extensions and they can naturally be integrated with constraint programming. Moreover, due to their explicit logical nature, they allow quite simple methodologies for program correctness. For these reasons, we believe that logic languages are natural candidates to deal with the difficulties of time-critical applications.The overall approach is to develop and integrate programming concepts related to time with existing concurrent (constraint) logic languages. More specifically, the overall approach is structured along the following lines: (1) identification and classification of the kind
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Highspeed prototyping using a foot analogue which mimics the thermo regulatory mechanisms of the human foot during walking'.

assistant: **Concept**

This project addresses two needs in the European footwear industry:- Reliable, i.e. can be correlated with real wear experience, moisture disposal and thermal properties assessment in finished footwear - Faster product development. To achieve these it is intended to produce a foot analogue, which mimics the thermo-regulatory mechanisms of the human foot during walking. This will be used for the basis of test protocols and guidelines, which will allow rapid, quantitative assessment of whole shoes, which can be correlated with real wear experience. Addressing these needs will strengthen the international competitiveness of the European footwear industry and help maintain jobs and skills within the Community. The industry manufactured 1200 million pairs in 1997 with an estimated retail value of 50 billion Euros. However, there is a continuing reduction in this manufacturing sector of around 5% per annum due to increasing competition from outside the Community.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Integration of emerging soft nanotechnology into the functionalisation of textiles' (NANOBOND) under Seventh Framework.

assistant: **Objectives**

One key area of the European textile industry is the technical development of products and processes for reducing contamination and the removal of stains of all kinds from manufactured articles, including textiles. To a large part this is necessary for keeping up performance and function, often for health reasons, although sometimes this is for purely aesthetic effects. Thus, easy-to-clean, soil release and antimicrobial properties are linked aspects that are of great importance such: health and avoidance of cross-contamination in medical textiles; improvement in comfort and freshness in consumer apparel; reduction of spoilage or wastage during storage and transport; increase useful lifetime of articles. These benefits further contribute to the overall goal of sustainable product development, to save energy and to protect our water resources. As alternative to commonly used biocidal chemicals, we propose a new surface modification concept that can control surface microbial contamination, particularly the development of bacterial colonies and biofilms.  Taking into account the needs of customers and environmental protection, the NanoBond Project aims to develop a new antimicrobial “soft nanotechnology” that comprises:  •Adaptability to a wide range of consumer and industrial applications.  •A responsive technology that adapts to the particular requirement for anti-microbial effect without “swamping” the environment with the un-restrained release of chemical antimicrobial agents, which is typical of other antimicrobial technologies.  •Highly-tailored solutions by altering the characteristics of the polymeric nano-film. The NanoBond Project will exploit the “soft nanotechnology” to create nano-structured and functional surfaces that can impart multiple beneficial propertie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Advancing Projections of Antarctic Ice-Ocean Interactions with Physics-Informed Neural Networks' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

The Antarctic ice sheet, a critical regulator of global sea level, is losing mass mainly through basal melting driven by warm Circumpolar Deep Water (CDW) intrusions. These are controlled by the Antarctic Slope Front (ASF), whose variability dictates when and where CDW can access ice-shelf cavities. Understanding these processes is limited by sparse in situ data, satellites’ inability to observe subsurface conditions, and the coarse or computationally expensive nature of existing ocean models.This project will develop CAPTSA (Circum-Antarctic Physics-informed model for Temperature, Salinity, and Advection), the first Physics-Informed Neural Network (PINN) framework to enhance our understanding of Antarctic ice-ocean interactions. CAPTSA will integrate satellite-derived data, limited in situ observations, and governing physical equations to reconstruct the daily full-depth structure of temperature, salinity, and circulation across the Southern Ocean and Antarctic shelves.By combining the flexibility of machine learning with physical consistency, CAPTSA will overcome challenges of data sparsity, coarse resolution, poorly constrained parametrization schemes, and computational cost. Its time series predictions will be employed in the analysis of  ASF dynamics, CDW intrusions, and cross-shelf exchanges across fresh, warm, and dense shelf regimes. Further, by linking the CAPTSA predictions with satellite- and radar-derived melt estimates, CAPTSA will allow causal attribution between external climate forcing, oceanic variability, and ice-shelf melt rates. This integrative approach will advance process-based understanding of ice-ocean feedbacks and provide a robust framework for regime-specific projections of basal melting and Antarctic contributions to sea-level rise.


**Keyw
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Stochastic and deterministic modelling of biological and biochemical phenomena with applications to circadian rhythms and pattern formation' (StochDetBioModel) under Seventh Framework.

assistant: **Objectives**

Classical deterministic mathematical description of the dynamics of chemical systems becomes invalid if the concentration of an involved chemical species is too low. In this case the noisy behaviour of individual molecules starts to be significant and considerable stochastic effects are observed. The stochastic models may exhibit even qualitatively different behaviour than the corresponding deterministic models. This situation is very typical in biological and biochemical systems.The collective behaviour of social insect, birds, or fish, bacterial chemotaxis, formation of skin patterns and the biochemical processes in living cells, like gene regulatory networks, the cell cycle, and circadian rhythms are examples of processes mathematically modelled by reaction and reaction-diffusion systems, we concentrate on in this project.We aim at general theoretical problems connected with stochastic and deterministic modelling of reaction and reaction-diffusion systems. For example the model reduction, bifurcation analysis of stochastic differential equations, high computational cost of stochastic models, and the interconnection and comparison of deterministic and stochastic approaches.In addition, we will apply the general theory and multipurpose computational tools to specific biochemical and biological systems of circadian rhythms and skin pattern formation. In particular, we will investigate whether the robustness with respect to noise observed in models of circadian rhythms is preserved if spatial aspects -- the diffusion -- is added to the model. Further, based on recent theoretical results, we will analyze the character of spatial patterns in reaction-diffusion systems with unilateral regulation. The unilateral regulation may increase the robustness of the pattern formation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The Mosaic Design Strategy: Application to Underwater Acoustic Functionalities' to be submitted under Horizon Europe.

assistant: **Abstract**

The MDS-APPThe MDS-APP-UAF action is supervised by Professor Vicente Romero-García at Instituto Universitario de Matemática Pura y Aplicada (IUMPA) at Universitat Politècnica de València (UPV), Spain.  This proposal is on the implementation of a novel ""mosaic design strategy"" to the fabrication of an underwater acoustic impedance tube prototype, as well as the realization of an underwater acoustic absorber with a broadband absorption spectrum and thickness that can surpass the causal constraint. The proposed project combines theoretical modelling, simulations, and experiments. The successful completion of this project can have commercialization implications with the attendant effect of propelling the research and development activities in the underwater acoustics area. The proposed action is seconded by the Laboratoire d’Acoustique de l’Université du Mans at Le Mans Université (LAUM). LAUM represents one of the largest acoustics laboratories in the European Union. Therefore, it will complement the mathematical and physical skills provided by IUMPA with the acoustics and mechanics needed for the project. Both IUMPA's and LAUM's activities range from basic research to industrial collaborations, with connections with many of the leading universities and research institutions in Europe. Both offer an ideal environment for the successful completion of this proposed project (including scientific management, dissemination and exploitation activities) and its subsequent trials prior to commercialization considerations. This inter-sectoral and inter-disciplinary action is also actively seeking cooperation with European acoustic companies, aims to extend the development of underwater acoustics in academic research and industrialization. It would also contribute to broadening th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'METHODS AND TOOLS INNOVATIONS FOR SEISMIC RISK ASSESSMENT' (METIS).

assistant: **Innovation**

The proposed project intends to translate research to practice through rigorous and efficient methodologies and tools to assess seismic safety of NPP. It also has the aim to innovate current practice by supporting simulation results with experimental data and experience feedback in the framework of Bayesian approaches and machine learning. The research will develop methods to improve the predictability of (non linear, best-estimate) beyond design analyses (design extension earthquakes). The refined seismic PSA provides meaningful support in the decision making process and could be useful for real time expertise of plant safety in case of temporary unavailability of safety relevant equipment or structures. It is also proposed to develop efficient tools to identify major contributors to risk such that efforts to increase safety and resistance are focused on relevant equipment. The outcome will thus increase the reliability of the analyses and in turn increase confidence in the probabilistic and deterministic safety assessment results. The results of this project will then help nuclear operators in their periodic safety reviews and to respond to the high-level EU-wide safety objectives of the amended EURATOM nuclear safety directive (stress tests). The considered accident scenarios will provide input for updating severe accident management guidelines (SAMG).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Interaction between migration, land and water management and resource exploitation in the oasis of the Maghreb' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

* To study the interaction between migration and changing land & water management with resource exploitation in the oases of the Maghreb.* To examine the ecological impact of the changes in land & water management and resource exploitation, especially their contribution to desertification processes.* To design a model for increased investments and improved spin-off of allocation of remittances in sustainable agriculture.Expected OutcomeBy identifying the main obstacles for investments in agricultural development and for sustainable land & water management, this interdisciplinary project should be able to identify the enabling conditions for successful promotion of a sustainable agricultural development of the region as well as for the struggle against desertification, which also contributes to the reduction of out-migration.The project concerns a comparative and interdisciplinary research in four oases in Southern Morocco and Tunisia. It will study the differentiated impact of migration and concomitant socio-economic changes on land & water management and resource exploitation in dryland oases and, consequently, its ecological consequences.The five work packages are: * Quantitative socio-economic survey on household level, focusing on demographic structure of the household, migration characteristics, activity patterns, income characteristics and investment patterns, as well as the agricultural exploitation. The impact of migration on decision-making related to resource exploitation among non-migrant groups will be equally studied.* Integrated socio-economic interviews with peasants on plot level, focusing on actual land use, irrigation patterns, and land & water conservation measures. In particular on this level the interdisciplinary nature of the research will be reali
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Imperfectly competitive systems of segregated markets'.

assistant: **Objectives**

Research objectives and content The objective of this project is the study of imperfect competition in a context with multiple markets for each commodity. which are segregated (physically or otherwise). Systems of regionally or internationally segregated markets are such examples. I plan to extend the stan- dard model of imperfect competition by introducing multiple trading posts for each commodity. In such a framework I intend to address the following issues: - Qualitative analysis of the model with multiple markets for each commodity, which are imperfectly competitive: structure and properties of equilibrium outcomes. - Imperfect competition as the source of price disparities across markets for the same commodity. - Application to international trade with imperfectly competitive markets: In international trade, systems of markets are segregated not merely by region but most importantly but by the fact that different currencies are accepted as means of exchange. I plan to focus on the effects of a common currency on relative prices, balance of trade and welfare across international systems of imperfectly competitive markets. Training contact (objective, benefit ant expected impact) The objective of this project is the rigorous study of imperfect competition across systems of markets. The benefit from this project is expected to be twofold: On the policy level the conclusions of this research are expected to be useful to policy-makers, as this project is directed to issues of monetary unification. On the scientific level I expect to produce articles for presentation in international conferences and for publication to scientific journals. The topic is a yet unexplored area of imperfect competition. I expect researchers from other fields of economics to benefit from this
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Development and Demonstration of Highly Insulating, Construction Materials from Bio-derived Aggregates' (ISOBIO) under Horizon 2020.

assistant: **Objectives**

The ISOBIO project will develop a new approach to insulating materials through the novel combination of existing bio-derived aggregates with low embodied carbon with innovative binders to produce durable composite construction materials. These novel composites will target 50% lower embodied energy and carbon than traditional oil based insulation panels, and will increase thermal insulation compared with traditional systems by at least 20%. By using bio-based materials, using vertical integration from raw material production through to finished systems, the ISOBIO project aims to reduce costs by at least 15% over traditional systems. The use of bio-based materials ensures that whole life energy use is reduced through taking advantage of the photosynthesis of atmospheric carbon which is sequestered in the fabric of the building for its lifetime. The ISOBIO materials take advantage of the natural moisture sorption/desorption characteristics of bio-based materials, which is known to passively manage the indoor environment resulting in greatly improved indoor air and environmental quality, whilst at the same time reducing the demand for air conditioning.


**Keywords:** Insulation, low carbon, composite, construction, bio-aggregate, moisture sorption, environmental quality, air quality, carbon sequestering, modular construction, panel, render