RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'DNA Methylation dynamics during Gastrulation'.

assistant: **Concept**

A fundamental aspect of biology is the understanding of how cell fates are established and maintained. Although it is widely accepted that epigenetic reprogramming is a central process of mammalian development, one of the most intriguing questions that remains unanswered is how DNA methylation marks contribute to cell differentiation and lineage commitment. By combining, novel single cell genomics techniques, CRISPR/dCas9 technology and innovative analytical approaches, this project will uncover the links between DNA methylation, gene expression and cell fate decisions during mouse gastrulation. This information will be used in a novel way to identify methylation signatures responsible for the stable repression of pluripotency, which has great potential to advance the development of safe iPS cells. Furthermore, this proposal will implement two innovative approaches utilising single cell DNA methylation patterns to reconstruct lineage trajectories of individual cells. This project capitalises on the unique combination of my novel analytical approaches, my background in DNA methylation analysis and evolutionary biology together with the extensive expertise in single cell techniques and developmental biology of the host lab. This multidisciplinary proposal will provide critical insights into how information is encoded in the epigenome and what this information can tell us about a cell’s history within a developing organism. These results will significantly advance the field of epigenetics, developmental and stem cell biology. Finally, the knowledge and skills gained from this project combined with my scientific and personal development will hopefully open up exciting career possibilities with the long-term goal to establish my own research group in Europe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Tackling Conspiracy Theories by Fostering Resilience and Political Self-Efficacy in Democracies' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Liberal and constitutional democracies in Europe are currently under massive pressure from authoritarian populism, culture wars and identity conflicts. A key issue is the erosion of trust in democratic institutions and the parallel rise in belief in conspiracy theories. The latter undermine democratic procedures as well as citizen engagement and create harmful political identities by exploiting the inherent vulnerabilities of democracies: their openness and the ambiguity of decision-making processes. These identities block political discourse with authoritarian narratives and hinder effective political action, threatening democracies from within.TaCT-FoRSED closes a scientific gap regarding the interrelation between democracy, identity formation and conspiracy theories. Using existing research and collecting new data, the project plans to a) investigate the impact of conspiracy theories on the adoption of an anti-democratic group identity and, conversely, to explore concrete identity factors that strengthen or weaken resilience to conspiracy myths. Based on the realisation that the complexity of value-pluralistic democracies is the counterpart to any simplistic, authoritarian friend-foe thinking of conspiracy beliefs, democratic identity formation processes are also seen as an opportunity to effectively combat conspiracy narratives.TaCT-FoRSED will therefore b) address its key target group of multipliers in the educational fields and develop OER that specifically promote democratic self-efficacy to foster a counter-identity to any conspiracy mentality. These materials will be evaluated together with relevant institutions from different target groups. The project will thus improve the legitimacy of knowledge-producing institutions and political parties by supporting demo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Methodology for archiving management process supported by information operation systems'.

assistant: **Concept**

When Public Administration decide to change their archiving process, they have to face lack of complete and updated models and methodologies together with decades or hundreds of kms of documents to be re-archieved. These processes mean a large number of public employees handling, sorting, cataloguing, storing, searching and retrieving large amount of documents and information every day. The current technologies and methodologies are more oriented to document filing rather than information provision or citizen's services, are supported by restricted and old cataloguing, and are not prepared to integrate and manage different types of archiving support. The project aims to provide a model, methodology and IT requirements to allow Archiving Processes in Public Administrations to be translated into operational organisation structures, and to be supported by appropriated technological applications.The goal is to allow organisations with a large amount of documents to migrate from current archiving management practice to that of the future more suitable for the new management techniques (decentralisation, human resources empowering, network operation, etc.) and to be supported by open information operation systems. MARCHIVE intends to re-engineer the process and to provide a methodology for implementing Archiving process by determining the coming future of archiving in the Information Society, needs and requirements, management (new organisations) and technology (I&CT) state of the art. And according with them, to determine the IT requirements for developing the appropriate tools and applications. By this, MARCHIVE will enhance the effectiveness and efficiency in our Public Administrations achieving dramatic reduction of duplicated efforts, time and cost, and important increas
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Smart Renewable Energy Manager for the Industrial Prosumer Market' (SREM).

assistant: **Innovation**

The progressive reduction in price of renewable energy and energy storage due to technology innovation and production enhancements is revolutionising the energy sector by turning the traditional centralised power system into a new decentralised one. Commercial and industrial (CI) consumers are increasingly implementing distributed energy resources (DERs) such as solar photovoltaic (PV), local batteries and electric vehicle (EV) charging stations in their facilities to lower their energy cost, increase security of supply and decarbonise the economy.By implementing an increasing number of DERs, CI consumers become prosumers (producers and consumers). Prosumers must manage their own generation, storage and consumption. Therefore, there is an urgent need to develop energy management tools able to cost-effectively integrate and operate generation, storage and loads. Moreover, new opportunities to make profit arise with the implementation of DERs (especially from the potential of the pair distributed generation plus storage) regarding the traditional scheme.SREM is an innovative Smart EMS specifically designed to fill the need to automate the management of loads and the increasing number of DERs in the CI market. Its differentiating and proprietary algorithms aim to achieve the highest financial return (15%-30% energy savings). SREM has been developed by Effinnova Management (Effinnova) a Spanish start-up company that is providing substantial economic savings through energy management services to its industrial and commercial customers and that has noted its customers urgent need to develop new energy management tools to integrate a growing number of DERs in their facilities aiming to reach economic gains, facilitate its operation  control and increase the security of supply.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Breast Cancer Risk after Diagnostic Gene Sequencing (BRIDGES)' (BRIDGES), addressing dissemination and exploitation.

assistant: **Impact**

Breast cancer affects more than 360,000 women per year in the EU and causes more than 90,000 deaths. Identification of women at high risk of the disease can lead to disease prevention through intensive screening, chemoprevention or prophylactic surgery. Breast cancer risk is determined by a combination of genetic and lifestyle risk factors. The advent of next generation sequencing has opened up the opportunity for testing in many disease genes, and diagnostic gene panel testing is being introduced in many EU countries. However, the cancer risks associated with most variants in most genes are unknown. This leads to a major problem in appropriate counselling and management of women undergoing panel testing.In this project, we aim to build a knowledge base that will allow identification of women at high-risk of breast cancer, in particular through comprehensive evaluation of  DNA variants in known and suspected breast cancer genes. We will exploit the huge resources established through the Breast Cancer Association Consortium (BCAC) and ENIGMA (Evidence-based Network for the Interpretation of Germline Mutant Alleles). We will expand the existing datasets by sequencing all known breast cancer susceptibility genes in 20,000 breast cancer cases and 20,000 controls from population-based studies, and 10,000 cases from multiple case families.  Sequence data will be integrated with in-silico and functional data, with data on other known risk factors, to generate a comprehensive risk model that can provide personalised risk estimates. We will develop online tools to aid the interpretation of gene variants and provide risk estimates in a user-friendly format, to help genetic counsellors and patients worldwide to make informed clinical decisions. We will evaluate the acceptability a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Homicide-Suicide in European Countries' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Homicides followed by the suicide of the perpetrator (hereafter HS) are a rare yet very serious form of interpersonal violence, which occurs mainly in partnerships and families. Little is known about the frequency and causation of these events. The aim of t he study is to collect data primarily from media archives on all cases of HS in a number of European countries, to compute population-based rates of HS for regions and countries, and to employ socio-demographic and survey data to explain area variances in the rate. The theoretical model draws on Durkheim's modes of social integration. Certain forms of violence are assumed to be more likely in highly integrated, 'collectivistic' social contexts. In addition, available data will be analysed with respect to socio-demographic profiles and victim-offender constellations.'
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'AUtomated Restoration of ORiginal film and video Archives' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Television channels, archivists and film producers all hold numerous archive programmes which, taken as a whole, make up a unique record of history, of artistic and cultural development and of all aspects of life in this century.Each type of video and film format has its own share of particular degradation, with problems increasing with each replay. Several videotape recorders are no longer manufactured or serviced by the manufacturers ; this situation resulting in increased maintenance and operating costs.As a result, archive holders must copy their collections onto new media, but the quality of the copy often remains well below today's standards, something which the general public, broadcasters and archive-based programme producers will be more and more reluctant to accept.The economic exploitation of this type of programme depends a great deal on their quality level.Solutions for restoring at an acceptable cost are therefore indispensable for the large-scale utilisation of television archives, thus contributing, through revenue generated, to the preservation of our audio-visual heritage.The objective of AURORA is therefore to develop a fast and effective video restoration system with the following characteristics :Real-time detection of impairments and estimation of quality level.Restoration in real time with control of level of correction by the user.Interactive restoration tools for high quality restoration or for badly damaged materials.An in-depth understanding of the impairments linked to the video recording technology, and the methodologies and algorithms to address them.A completely integrated set of techniques for exploiting the large stock of archive TV programmes : methodologies, algorithms, and real-time hardware.The demonstrators will prefigure future pro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Thermal-aware Resource Management for Modern Computing Platforms in the Next Generation of Aircraft' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The THERMAC project aims to investigate, develop, and validate emerging thermal-aware software-based techniques that will reduce operating temperature of avionic computing platforms  in small aircraft transports. The project specifically targets the integration of multicore and GPU-based platforms in avionics from a thermal perspective. The expected impact of the improved thermal performance will improve dependability, computing performance, and will reduce size and weight of electronics due to relaxed dissipation requirements and the higher number of functionalities that can be integrated in the same computing platform.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Theory of Ultra-Cold Atoms in Lattices'.

assistant: **Objectives**

This proposal concerns the theoretical investigation of ultra-cold atoms in lattices, with special attention to the strongly correlated regime. The scientific objectives consist in the application of innovative methods for strongly correlated systems to describe novel physical situations, obtained through the engineering of the Hamiltonian.We will solve the Bose-Hubbard Hamiltonian using the Gutzwiller ansatz, the dynamical mean-field (DMF) method, the time-evolving block decimation (TEBD) method, as well as exact numerical solutions for small systems. The DMF and the DEBD are respectively a traditional method in condensed matter physics and a completely innovative method for slightly entangled systems, which look very promising for the study of ultra-cold gases.First, we will devote our attention to the study of the excited states and the dynamics of ultra-cold dipolar atoms in a lattice. We will investigate in particular whether the system is characterised by a multitude of almost degenerate states and how in this respect it compares with disordered systems. Our final aim is to draw the bridge with possible applications as neural networks or quantum memories.Second, we will investigate the physics of ultra-cold atoms in non-abelian gauge fields in a lattice, starting from the single particle behaviour (presently under investigation), to the weak interacting (mean-field) and strongly interacting (correlated) regime. Our ultimate goal is the investigation of Berry phases, non-abelian Aharonov-Bohm effect and area or perimeters laws for Wilson or t'Hooft loops.The training objectives of the proposal are aimed to bring the applicant to master the named techniques and acquire experience in multidisciplinary fields, ranging from neural networks, quantum field theory and qua
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'CellPROM - Cell Programming by Nanoscaled Devices' to be submitted under Sixth Framework.

assistant: **Abstract**

We will develop a new generation of nano-biotechnological equipment, the CellPROMs. As the EPROM paved the way to a broad application of microelectronics, CellPROMs will overcome current limits of and revolutionise the existing handling technologies and procedures by automated, compact and parallel yet still individual handling of large numbers of cellular samples.Typical targets will be animal and human adult stem cells. Human embryonic stem cells will not be used. The main task of our IP is to develop procedures and devices for the precise creation of NanoScapes - individually tailored nanoscaled macromolecular landscapes, which will allow, for the first time, to non-invasively produce well-defined populations of individually programmed cells, eventually leading to substantial breakthroughs and numerous applications in the fields of molecular medicine and cellular nano-biotechnology. Although surface imprinting of cells will be realised via artificial nano-biotechnological devices, e.g. nanostructured stamps or beads, these tools are designed according to the natural principles of cellular signalling and differentiation. As nanocomponents are essential to the imprinting process, suitable techniques and principles to form nanoscaled macromolecular patterns on arbitrary surface geometries have to be developed. All components, ranging from the nanoscale of functional interfaces up to the macro level for cell handling, are to be developed as functional modules suitable for further application.The project features multiple nano- and biotechnological challenges. To tackle these, will lead to breakthroughs in nanotechnological device development and, moreover, drastically advance our understanding of biological signals relevant to cellular programming. Once available, CellPR
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'MEmbrane DIstillation in Remote AreaS', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The overall objective of the MEDIRAS project is the development and demonstration of cost effective and very reliable solar driven desalination systems for water scarcity affected regions with high insolation. The modular system set up is based on the highly innovative Membrane Distillation (MD) technology. MD is favorably applicable for small distributed desalination systems in the capacity range between 0.1-20m³/day. MD is very robust against different raw water conditions and operable with alternating energy supply like solar energy. With respect to demonstration and market penetration of MD systems, the project will be focused on cost reduction and quality improvement for life time extension of MD modules and MD systems, on the development of components such as brine cooler and brine disposal units for ground water desalination at inland locations with limited raw water resources, and on the development of scalable system configurations in order to adapt them to different customer demands. Solar energy driven units for potable water disinfection will be integrated into the desalination units for health protection. The emphasize of the MEDIRAS project is on the design, set up and operation of different demonstration systems. Three compact systems of different sizes (150l/day and 300l/day) and two multi module two loop systems (3m³/day and 5m³/day) for full solar energy supply and for combined solar and waste heat energy supply will be installed in different European potential user sites in , Gran Canaria (Spain), Tenerife (Spain) and Pantelleria (Italy), as well as in Tunesia as an example for an North-African country. Comprehensive performance evaluation and water quality analyses will be conducted. With respect to market penetration in addition to the technological