RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'High throughput spectroscopy atomic force microscopy for the foot printing of bacteria and cellular organelle' (HighTPSAFM) targeting Horizon 2020.

assistant: **Abstract**

The project HighTPSAFM (High throughput spectroscopy atomic force microscopy for the foot printing of bacteria and cellular organelle) intends to develop and implement high throughput and high resolution modes of atomic force microscopy (AFM) with spectroscopy-like capabilities and enhanced sensitivity to detect and identify heterogeneous compositional contrast. The aim is to develop the instrumentation in order to answer and elucidate mechanisms of timely questions in molecular and cell biology, i.e. related to the Histone Code Hypothesis and bacterial resistance. Unresolved requirements involve simultaneously be minimally invasive while providing high throughput, high resolution and spectroscopic capabilities, such as chemical identification, or footprinting in the case of bacteria, cells and other biological systems, with high sensitivity. The applicant has already gained international recognition for his achievements in the field and become an emerging scientist of note. The project further represents a significant advance in the applicants’ career by expanding it towards applications in the fields of biotechnology and complementary optical techniques. The project will establish the candidate, and collaborators, in the field by building a European interdisciplinary and international team of growing stature and recognition.  The project includes the building of a competitive network of collaborators in Europe with partners that will jointly serve to support and systematically fulfil the objectives.  The two year project will further provide sufficient experience to the candidate as an independent researcher while being supported by an international referent in nanotechnology with state of the art infrastructure and facilities at of the Universidad de Murcia UM (CIOyN
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Scaling up early and late effects research in Lithuanian childhood cancer survivors through education and twinning'.

assistant: **Innovation**

The SCARLET (SCAling up early and late effects Research in Lithuanian childhood cancer survivors through Education and Twinning) proposal aims to increase scientific excellence and innovation capacity at Vilnius University Hospital Santaros Klinikos (VULSK) and its affiliated entity National Cancer Institute (NCI) by scaling up research activities in Lithuanian childhood cancer survivors (CCS). The area for twinning was defined based on the emerging importance of survivorship research due to the increasing number of CCS in Europe and identified gaps in Lithuania. The key challenges addressed in the proposal are 1) lack of data on the prevalence of CCS in Lithuania exploitable in research initiatives; 2) poor transition from paediatric to adult care depriving young CCS over the age of 18 of advantages of surveillance in a research context; 3) the need to implement innovative solutions for monitoring and prevention of early and late effects through joint research activities; 4) suboptimal competences in management and administration of large-scale research projects. Four research-intensive institutions from 4 European countries will bring to the consortium their specific expertise to address identified shortcomings. The proposal aims to build on and exploit current shared research initiatives that will be leveraged to achieve SCARLET’s goal and objectives. The twinning exercise will be implemented through secondments of Lithuanian staff to the partner premises and engagement in the research activities led by partner institutions, organisation of educational events, and participation in knowledge-of-transfer meetings. As a result of the twinning activities, VULSK and NCI will improve their research profile and reputation, international visibility, and attractiveness. The e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Towards an active bypass for neural reconnection' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

ByAxon is devoted to the development of a new generation of sensors and electrodes based on nanotechnology materials for neural interfacing. We aim to design and build a prototype of an active implant that could work directly at the spinal cord (SC) level. This implant will be primary focused on restoring the transmission of electrical signals in the injured SC, acting as an active local bypass, something not possible with current technology. Further applications might include deep brain stimulation or retinal implants, among others.Current neural interfacing approaches are based on detecting electric potentials at the brain level, and/or triggering functional electrical stimulation (FES) through electrodes at muscular or SC levels. Important present drawbacks are the large number of cables and electrodes they require and, specially, the lack of sensory feedback. The ultimate non-contact sensing devices (magnetoencephalography) detect magnetic-field pulses generated by potentials at the brain, but require cryogenic temperatures, and, hence, are not portable. We will exploit here the enhanced properties of nanostructured materials to develop improved room temperature magnetoresistance-based high-resolution magnetic sensors. This will allow tackling not only the brain but also the SC directly. We pursuit a novel integrated interface comprising both sensing and stimulation at the SC level. To reach this aim, we will develop FES electrodes of enhanced adhesion and efficiency by using nanowire coatings.ByAxon is supported by an interdisciplinary consortium, going from material scientists and electronic experts to biologists and clinicians. Our nanotechnology-based approach offers a novel perspective and will be complementary to, but independent from, present neural regenerat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Implementing configuration management in very small enterprises' under Fourth Framework.

assistant: **Concept**

Very many small software companies, often having started as a one man enterprise, reach a stage were version/configuration management and error tracking/reporting systems becomes a must. This because more people are getting involved in the software development, the firm gets more (and more heterogeneous) customers, and the applications themselves no longer require less major changes, but routinized error fixing and minor functionality adjustments. Very often one finds profit margins eroded by unforeseen troubles by lack of version / configuration control, no system for keeping track of errors reported/fixed/tested etc.THE EXPERIMENTICONMAN aims to implement lightweight configuration management procedures for very small enterprises that cannot use the same approaches as larger companies. The procedures will be based on the current software engineering practice of the partners in order to be as simple an unobtrusive as possible. The use of configuration management will also address documentation and error reporting. There are three very small firms (5- 10 persons) involved all of them having a basic product that is delivered in customised versions for different purposes and to different customers. An important element in the experiment is to exchange experiences with different configuration management tools and routines used. The project will define and test a set of software metrics in order to get quantitative information of the impact of the new configuration and error-reporting regime. EXPECTED IMPACT AND EXPERIENCEAfter the experiment the three companies will have implemented procedures for revision and configuration management, that includes testing of new configurations/versions of the base product, including both source code and documentation. In addition there wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project '(Mal)adaptative beta-adrenergic regulation of the cardiac voltage-gated sodium channel, Nav1.5' (Mal) targeting Horizon Europe.

assistant: **Abstract**

Cardiovascular disease is a leading cause of morbidity and mortality in Europe and, in the face of population aging, this statistic is predicted to significantly worsen. One of the major CVD risk factors is represented by the alterations of beta-adrenergic receptors stimulation, which modulates the function of the voltage-gated sodium channel, Nav1.5, in cardiomyocytes. In a healthy heart, beta-adrenergic receptors regulate the function of Nav1.5 to potentiate cardiac contraction during common everyday activities like physical exercise. However, the same pathway promotes and worsens cardiovascular disease such as heart failure. Thus, there is an urgent need to investigate how a healthy physiological response becomes deleterious in order to better understand cardiovascular disease occurrence and hence to improve its treatment. MALBENA will address this challenge through an ambitious and interdisciplinary study that will thoroughly assess molecular and functional modifications of Nav1.5 in the beta-adrenergic receptor-stimulated cardiomyocytes as well as in human failing and non-failing hearts. Such profiling of the physiological and pathological remodeling of Nav1.5 will provide a substantial impact on the novel strategies developing targeted therapies aiming to reduce the cardiovascular disease burden and, at the same time, having little to no side effects on the other organs, since Nav1.5 is nearly exclusive to cardiomyocytes. The combination of unique expertises of the host supervisor, Dr. Céline Marionneau, in phosphoproteomics of Nav1.5, and of the researcher, Dr. Oksana Iamshanova, in Nav1.5 functioning as the macromolecular complex, will enable synergistic implementation of the scientific backgrounds, techniques, and methods to guarantee the successful achievement
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Risk Estimation of Rocking Components Subjected to Ground Motions.'.

assistant: **Objectives**

This Career Integration Grant will support me during my transition from a postdoctoral scientist in Columbia University in NYC to a University Lecturer at the University of Oxford. It will allow my proper reintegration to Europe, since I originally come from Greece but have been studying in the US for the last 5 years (4 years PhD -1 year Postdoc). Success within the targets of this CIG project will allow me to become a permanent Lecturer at the University of Oxford after 5 years and hence a permanent member of the ERA. The CIG will provide me with substantial research budget that will also allow me to attend several conference and disseminate my work as well as creating collaborations within the European and international research communities. Below follows a short description of the project:A wide range of structural and non-structural elements are not tied or bolted to their support medium and thus are free to experience large displacements and rotations when subjected to ground motions. Their response is in general a three dimensional motion where rigid body modes such as: sliding, bouncing, spinning and swiveling (when casters are used) and rotating with respect to a vertex of the body may dominate the response to a lesser or greater extent, depending on the properties of the body, its support medium and the ground motions characteristics. This rich non-linear 3D response may overall be characterized as rocking.  This research will develop new models that accurately describe the behavior of rocking objects, quantify the associated risk and suggest solutions to minimize it.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Innovative Circular Economy Based solutions demonstrating the Efficient recovery of valuable material Resources from the Generation of representative End-of-Life building materials' (ICEBERG).

assistant: **Concept**

ICEBERG will make significant advances in the uptake of the circular economy in the building industry through the development of innovative circular reverse logistics’ tools and high-value secondary raw materials production technologies to establish market confidence and acceptability of recycled End-of-Life building materials (EBM). ICEBERG aims to design, develop, demonstrate and validate advanced technologies for the production of high-purity secondary raw materials (>92%w) through 6 circular case studies (CCS) across Europe, covering circularity of wood, concrete, mixed aggregate, plasterboard, glass, polymeric insulating foams and inorganic superinsulation materials. ICEBERG will generate cross-cutting integrated smart solutions that encompass three innovative circular reverse logistics’ strategies: an upgraded BIM-aided-Smart Demolition tool; a novel digital EBM traceability platform; and Radio Frequency and QR based identification system. ICEBERG will develop novel technologies for the recovery of EBM, which include: hyperspectral imaging (HSI), machine-learning software and robotic manipulators to increase sorting efficiency of mixed aggregates; an integrated crushing, sorting and cleaning optimized system and fast pyrolysis and purification processes for wood fractions; thermal attrition mobile unit integrated with LIBS and carbonation for concrete; hydrocyclone combined with HSI sorting and acid purification to increase the purity of recycled plasterboard; a combined process of purification and solvolysis for polymeric insulating foams; advanced hydrothermal and supercritical based processing of glass and silica containing waste. Circular design solutions for greater circularity of EBM and production of innovative circular building products with high purity an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Giant resonance decay studies: a means to constrain fundamental properties of nuclear matter' to be submitted under Sixth Framework.

assistant: **Abstract**

Giant resonances correspond to a collective motion involving many if not all the particles in the nucleus. The restoring forces for these high-frequency density or shape vibrations are directly related to the fundamental properties of the nucleus and the nuclear matter. Such relevant properties are the nuclear incompressibility and the symmetry energy term of the effective nucleon-nucleon interaction.The experimental observation of the decay channels of the giant resonances offers a unique possibility to learn about their microscopic structure and damping mechanism. In addition, the selection of the direct particle decay channels is especially of fundamental importance since it drastically helps to suppress the background and the nuclear continuum, and enables a more precise definition of the giant resonance strengths, which leads to a more stringent test of the microscopic descriptions. The primary goal of this project is to prepare and perform coincidence experiments on the direct-proton decay of the least-known, high-lying giant resonances, which are mainly overtone modes.These studies will focus on the collection of systematic decay data of the isoscalar giant dipole resonance and on the search for an unambiguous evidence for the existence of overtone modes of the isoscalar giant quadrupole and monopole resonances. The proposed studies will provide an effective reintegration of the applicant to the host institute, which offers the suitable scientific excellence to successfully achieve the research objectives presented by the applicant.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Strong constraints on the nature of dark matter and astrophysical sources from multi-wavelength analysis of the Inner Galaxy' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

We propose a vigorous program of multi-wavelength and multi-messenger studies using several existing and upcoming data sets to substantially improve the sensitivity of dark matter searches as well as offer new insights into astrophysical sources of emission.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Research models in infection, cancer and regeneration: replacement and translation' (REMODEL) under Horizon 2020.

assistant: **Objectives**

REMODEL combines the existing local expertise in bioengineering, cancer and infectious diseases with partners at the frontline in developing organoid systems, manipulating them to fit specific purposes and validating their use as models, in order to build capacity to work with innovative model systems that can replace animal experiments and increase translational relevance. In doing so, REMODEL addresses a key issue in today’s biomedical research: how non-animal model systems can be developed to meet the needs for translationally relevant research in the era of precision and personalized medicine, whilst at the same time accounting for societal pressure to replace animal experiments. REMODEL will capacitate the coordinating institution, IBMC-i3S, through the establishment of organoid advanced in vitro models and their customization for the main areas of research (infection, cancer and tissue regeneration). REMODEL will contribute to raising the research profile of the institution and scientific skills of its staff developed through training schools and short-term scientific training periods as well as transferable skills training and mentoring of Early Stage researchers, but also through staff participation in international conferences presenting work within the REMODEL themes / framework. Organoids as experimental models are at the frontline of methodological development in biomedicine, and demonstrating competence in working with such models will place i3S in the spotlight in an international research context, and make the institution an attractive partner for future collaborations beyond the REMODEL network. On the European level, REMODEL represents an important initiative to bring together key partners in the development of innovative models to overcome the present
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Building an European Research Community through Interoperable Workflows and Data' (ER-flow).

assistant: **Innovation**

ER-flow will build a European Research Community to promote workflow sharing and to investigate interoperability of the scientific data in workflow sharing. The project will disseminate the achievements of the FP7 SHIWA project, particularly the coarse-grained workflow interoperability based on the SHIWA Simulation Platform. It will target major research communities that use workflows to run their experiments on a regular basis. The project includes four major research communities: Astrophysics, Computation Chemistry, Heliophysics and Life Sciences. They will be supported to run experiments with the simulation platform. Beyond these communities the project will strongly collaborate with the National Grid Infrastructures through EGI.eu in order to identify and involve further major research communities which either already use workflows or which are perspective workflow users. The research communities will select workflows which can be used as pilot workflows in particular research area of a particular research community to demonstrate how to develop, use and share workflows. The project will port these pilot workflows to the simulation platform and publish them in a workflow repository. The pilot workflows first, will demonstrate how to use the simulation platform; secondly, researchers can use these workflows in their experiments; thirdly, they can modify them to create their own workflows. The pilot workflows will help to create a critical mass of workflows to enable workflow sharing inside and between research communities. ER-flow will collect and analyse requirements of the supported research communities towards interoperability of scientific data in the workflow domain. It will investigate existing protocols and standards that support this interoperability. The pro