RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Bringing Obesity to Light - Do obesogenic chemicals affect lipid metabolism through changes in circadian rhythm?' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Bringing light to obesity will elucidate the interconnecting steps of two important signaling pathways i.e. circadian signaling and lipid metabolism. An increase in serum cholesterol level in shift workers indicates this link. Also obesogenic chemicals might influence lipid metabolism through changes in circadian rhythm.Research on obesity has gained in importance as the number of affected patients increases world-wide. The WHO lists five European countries in the top 23 states regarding obesity incidence. Moreover, the mounting healthcare costs turn obesity research to a hot topic. With OBELIX and EUCLOCK the EU already funds projects on obesity and circadian rhythm. This proposal joins both topics and links them to toxicology.The main goal is to study the role of circadian rhythm in lipid metabolism and obesogenic effects of chemicals. To elucidate the signaling pathway of environmentally induced obesity the zebrafish a model for genetic and physiological studies will be used.How do alterations in circadian rhythmicity influence lipid metabolism? How do the clock gene rev-erbα and the peroxisome proliferator activated receptors connect circadian and metabolic signaling pathways? Do obesogenic chemicals influence lipid metabolism through changes in circadian rhythm? A multidisciplinary approach will be made using toxicological, physiological, molecular biological and genetic methods in wildtype and transgenic zebrafish larvae and cells.The project will be done at Dr. Juliette Legler’s lab at the Institute of Environmental Studies at the VU University Amsterdam. Dr. Legler already proved to be an expert in ecotoxicological studies in particular regarding obesogenic chemicals. In addition her broad experience in project management and scientific supervision will allow th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Biopolymer based Single-Ion Conducting Gel Polymer Electrolytes for  Highly Performant and more Sustainable Batteries'.

assistant: **Innovation**

To properly ensure safe batteries, the development of safer and more environmentally-friendly ‘green’ electrolytes is urgently needed. The research aim of this project is to create performant single-ion conducting gel polymer electrolytes (SIC GPEs) from bio-sourced, abundant, reliable and low-cost materials such as cellulose, chitosan, agarose and alginate. This fellowship will address the electrolyte development from raw material to its application in a sodium-ion battery. The success of this proposal will be achieved by combining the knowledge and expertise of different laboratories. The synthesis and characterisation of the electrolyte will be realised at the Max Planck Institute of Colloids and Interfaces (MPIKG), Germany, where the fellow will be hosted under the supervision of Prof. Markus Antonietti. The advanced electrochemistry analysis will be carried out during the fellow’s secondments at Institute of Materials Science of Barcelona (ICMAB), Spain, with Prof. Rosa Palacín and Dr. Alexandre Ponrouch. The implications of practical realisation will be evaluated by Volvo Cars Corporation, Sweden, under the mentoring of Dr. Hanna Bryngelsson. The fellow will ensure the connection between the different laboratories’ expertise and will so also extend each partner’s research focus. During the 2-year project, the fellow and mentors will disseminate their results to both industry, academia and the general public through patents as well as articles in newspapers and scientific journals.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Translational Research on Combating Antimicrobial Resistance'.

assistant: **Objectives**

The health care systems of most European countries are based on a continuum from acute care hospitals, though other health care facilities to the community. Such a framework provides the perfect opportunity for the wide-spread dissemination of high-risk resistant clones or genetic resistant elements.  The driving concept of TROCAR is to investigate the fundamentals of the epidemiology of new highly virulent multiresistant strains of methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus spp., Extended-spectrum, metallo- and acquired AmpC beta-lactamase producing Enterobacteriaceae, multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii will focus on three major strategic aims: 1. The definition of the major high-risk resistant clones based on an appropriate representative collection and new clinical strains obtained during molecular epidemiological studies, in hospitals and laboratories collaborating with their respective National Excellence Laboratories in European countries using a standardised protocol. 2. The promotion of collaborative European research to investigate, by genomic and proteomic approaches, specific traits associated with virulence, transmission, persistence and resistance of epidemic clones in comparison with non-epidemic clones as well as resistance determinants and their genetic location in horizontal gene transfer units and their genetic environment. 3. The development of bioinformatics tools to fully exploit the genomics data and allow the rapid identification of resistant strains with heightened epidemic potential.  By combining the outputs of the project it will be possible to provide tools for monitoring the spread of key community and nosocomial pathogens, to provide the scientific basis for an early wa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Debating Deltas: The early medieval river mouth’s historical ecologies (6th-10th centuries AD). An interdisciplinary and comparative approach' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

This project will pursue an interdisciplinary methodology to analyse how and why the early medieval European deltas became primary gateways for interaction between sea and inland territories, and how they influenced the new socio-economic scenario after the fall of the Roman economic system. I will compare two Mediterranean cases, the Rhone and the Po deltas, with the North Sea cases of the Rhine and Elbe deltas between the 6th-10th centuries AD. Historical document and archaeological analyses in one of the most-active research clusters of early medieval Europe (UrbNet) will be paired for the first time in these areas with new cutting-edge remote-sensing technologies and network modelling analysis, allowing to: a) reconstruct the early medieval delta’s landscape; b) understand how deltas’ environment influenced the form and development of socio-economic networks; c) assess what kind of impact people and goods had on deltas and related societies; and d) identify and, possibly, define a ‘delta identity’ establishing a new research trend.De.ltas, through its interdisciplinary approach and the support of leading scholars in both archaeological (Sindbæk) and landscape (Kristiansen) analysis of wetland environments, has the potential to highlight the crucial socio-political and economic role of interaction in delta areas, reassessing the opinion of an early medieval socio-economic stagnation in the Mediterranean in this phase. Moreover, the case-study areas, at the borders of the post-Roman ‘European Union’ under the Franks, will allow me to investigate the permeability of delta societies engaging with migration, cultural integration and self-definition, and the anthropic interaction with climate change and environmental threats which are pressing contemporary issues. Finally
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'A Hungarian Night for Researchers 2008' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The 2008 edition of the Researchers’ Night is an expanded and updated version of the 2007 event. Tempus Public Foundation together with 13 prestigious institutions of the Hungarian higher education and research community - University of Technology and Economics; Corvinus University of Budapest; Eszterházy Károly University; Eötvös Loránd University; Pázmány Péter Catholic University; Szent István University;  Széchenyi István University; University of Debrecen; University of Miskolc; University of Pécs; University of Szeged; University of West Hungary, and the Agricultural Research Institute of the HAS - undertake the organisation of the event in 2008. The consortium consists of last year’s RN partners strengthened by two other universities. Our event fits well in the Europe-wide festival series with the entertaining and serious, but “user-friendly” scientific programmes focusing on science and researchers, and on researchers and society. We wish to involve the public in a wide range of various activities including hands-on experiments, laboratory and cave visits, creative contests, University CSI, music and theatre performances, exhibition of research results, investigating order and disorder in nature, an obstacle race in a Botanical Garden, a library night, games on wildlife, programmes linked to Renaissance Year, The Year of the Bible, and to the International Year of Languages initiatives and innumerable other exciting programmes. Visitors will meet and play with many researchers and get more acquainted with the world of science. The events will take place in 15 towns; most of Hungary will be covered ensuring that the RN will reach a large audience. The professional background and organizational experience of the participants ensure that the activities will be effi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Genomic and Environmental factors of Resilience to Early-life Stress' (GENRES), addressing dissemination and exploitation.

assistant: **Impact**

Early life stress (ELS), ranging from prenatal to postnatal challenges such as household dysfunction and child maltreatment, often co-occurs and affects over 60% of individuals worldwide, leading to adverse outcomes like psychosocial difficulties. However, individual responses to ELS vary, with some exhibiting remarkable resilience, such as maintaining high functioning or gradually improving. The GENRES project aims to uncover how genetic and environmental factors interact to foster resilience in individuals exposed to ELS. Using data from four large-scale population-based cohorts, GENRES will identify resilient developmental trajectories from childhood to adolescence and adulthood across emotional, behavioural, and cognitive functions. The project will analyse polygenic profiles (based on multiple polygenic scores) and environmental profiles (derived from multi-systemic family and social factors) that contribute to resilient trajectories (e.g., recovering or competent). Differential susceptibility effects will be tested, focusing on how sex, genetic predisposition, and temperament interact to influence individuals respond differently to environments, both negative and positive. The findings from each cohort will be integrated through meta-analysis, offering a comprehensive understanding of resilience to ELS across diverse populations and contexts. By bridging genetic and psychosocial research, the project will also contribute to a broader understanding of resilience, reducing stigma and shifting the focus from individual blame to systemic support. The outcomes of GENRES will inform public health strategies and interventions tailored to individual genetic profiles and resilience-promoting environments. Executing this project at the Max Planck Institute for Psycholinguis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'A computational approach to early language bootstrapping' (BOOTPHON).

assistant: **Concept**

During their first year of life, infants become attuned to the phonemes, words and phonological rules of their language, with little or no adult supervision. After 30 years of accumulated experimental results, we are still lacking an account for the puzzling fact that these 3 interdependent components of language are acquired not sequentially, but in parallel. Drawing tools from Machine Learning and Automatic Speech Recognition, we construct a model of this early process, test it on 2 large spontaneous speech databases (Japanese, French and Dutch) and test its predictions in infants using behavioral, EEGs and fNIRS techniques.1. Coding. We study different ways of defining coding features for speech, from fine-grained to coarse grained, in view of the automatic discovery of a hierarchy of linguistic units. We compare this with a systematic study of the units of speech coding as they unfold in 6, 9 and 12 month old infants..2. Lexicon. Infants recognize some words before they know the phonemes of their language; we modify existing word segmentation algorithms so they can work on raw speech. We test the unique prediction that infants start with a large lexicon that’s quite different from the adult one.3. Rules. Phonemes are produced as overlapping, coarticulated gestures. To untangle these context effects, we use a predictive model of coarticulation in auditory space and invert it. We test when and how infants perform reverse coarticulation.4. Integration. The above subprojects provide only an initial bootstrapping into approximate phonemes, words, and contextual rules. We show how to iteratively integrate these approximate representations to derive better ones. The outcome will be numerically assessed on an adult directed and infant directed speech database, and compared
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'European Network for Advanced Research on Olfaction for Malaria Transmitting Insect Control' under Seventh Framework.

assistant: **Concept**

The specificity of odor recognition by Anopheles gambiae odorant binding proteins (OBPs) and odorant receptors (ORs) will be investigated and correlated with quantifiable physiological and behavioral responses. For olfactory proteins involved in the detection of human hosts, OBP-OR pairs residing in common antennal olfactory sensilla and recognizing common host-related ligands will be identified using high-throughput screening assays employing purified recombinant OBPs, reconstituted insect cell-based OR expression platforms and libraries of synthetic and natural compounds. OBP crystal-based structure determination and modeling of ligand fitting into OBP and OR ligand-binding pockets will also be carried out in order to design ligand mimetics with improved binding and functional properties. The effectiveness of newly identified ligands will be established by in vivo electrophysiological and behavioral assays on female mosquitoes. Finally, lead compounds acting as disruptors of normal olfactory and host seeking mosquito behavior but lacking mammalian cell toxicity will be tested in model sites in Africa where A. gambiae (and malaria) is endemic to determine efficacy characteristics under conditions that simulate the sites of possible application of newly developed products.  This approach to dissecting mosquito vector olfactory function should yield results that will enhance our understanding of the mechanisms that control odor recognition in mosquitoes.  The identification of multiple disruptors of host seeking behavior of female mosquitoes will provide multiple new and effective tools to be employed in the effort to reduce the incidence of contact between the human host and the insect vector carrying the malaria parasite. Last but not least, the outcome of the proposed
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Smart Eyes: Attending and Recognizing Instances of Salient Events' (SEARISE), addressing dissemination and exploitation.

assistant: **Impact**

The SEARISE project will develop a trinocular active cognitive vision system, the Smart-Eyes, for detection, tracking and categorization of salient events and behaviours. Unlike other approaches in video surveillance, the system will have human-like capability to learn continuously from the visual input, self-adjust to ever changing visual environment, fixate salient events and follow their motion, categorize salient events dependent on the context. Inspired by the human visual system, a cyclopean camera will perform wide range monitoring of the visual field while active binocular stereo cameras will fixate and track salient objects, mimicking a focus of attention that switches between different interesting locations. The core of this artificial cognitive visual system will be a dynamic hierarchical neural architecture – a computational model of visual processing in the brain. Information processing in Smart-Eyes will be highly efficient due to a multi-scale design: Controlled by the cortically plausible neural model, the active cameras will provide a multi-scale video record of salient events. The processing will self-organize to adapt to scale variations and to assign the majority of computational resources to the informative parts of the scene. Smart-Eyes will be tested in real-life scenarios for observation of large crowded public spaces and of individual activities within restricted areas.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'AI-BASED PERSONALISED CARE FOR RESPIRATORY DISEASE USING MULTI-MODAL DATA IN PATIENT STRATIFICATION', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

AI4Lungs will develop and validate novel AI-based tools and computational models to improve patient stratification optimising diagnosis and treatment of infectious and non-infectious respiratory diseases. Diagnosis of respiratory disease comprises a complex assessment of several multiple exams over time that together characterise the patient condition. Streamlined into existing clinical pathways, AI4Lungs will support clinicians and other stakeholders in decision making along the patient journey from initial suspicion to diagnosis, and treatment planning. The models incorporate clinical partners’ multiple data sources, registries and open national/international databases, including multiple data types from medical records, imaging data as well as novel data from digital stethoscope and –omics. AI4Lungs stratification strategy will build computational models employing structured and unstructured data modalities, leading to more accurate positioning of patients and enabling them to benefit from global data and knowledge shared during all stages of care, focusing on diagnosis and treatment planning. With scale up, AI4Lungs will support any patient from any country, any hospital no matter how remote or small, by stratifying them among all of Europe’s patients from that cluster, gaining access to the collective expertise, experience and information on optimal care options. In parallel, health systems will reduce costs and effort in unnecessary testing, ineffective treatments and emergency services, optimizing use of health technologies and resources. AI4Lungs patient stratification tools will focus on respiratory diseases, a complex and broad set of disorders with high disease burden. AI and real world data combined with innovative holistic diseases modelling, will offer a s