RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Cell Migration under Mechanical Constraints' (DURACELL).

assistant: **Concept**

Control of cell migration is crucial for many biological processes. Cells sense mechanical cues to guide their migration. As opposed to passive materials, living cells actively respond to the mechanical stimuli of their environment through the transduction of mechanical information into biochemical signaling events. These responses, particularly to rigidity, include differentiation, migration and alterations in cell-matrix and cell-cell adhesion and thus occur over a wide range of time and length scales. I propose to address the effect of substrate mechanical properties on cell migration using quantitative in vitro methods based on micro-fabrication and micro-mechanical techniques. My main objectives are to:1/ Discover specific mechanisms that guide single cells toward stiffer substrates (a process known as durotaxis), investigate the range of stiffness-sensitive responses and determine the molecular mechanisms based on actin dynamics and cell adhesion assembly. 2/ Characterize the emergence of coordinated cell movements and thus how cells move in concert under external mechanical constraints. In addition to cell-substrate interactions, the role of cell-cell junctions is crucial in the transmission of mechanical signals over the cell population. By analyzing tissue dynamics at both mesoscopic and molecular scales, we hope to unravel how epithelial cell sheets mechanically integrate multiple adhesive cues to drive collective cell migration.3/ Elucidate the role of 3D mechanical environments in collective cell migration. In contrast to migration in 2D, cells in 3D must overcome the biophysical resistance of their surrounding milieu. Based on optical and innovative micro-fabrication techniques to modify the stiffness of 3D scaffolds, we will study its influence on cell mig
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Flavour, odour and texture improvements of plant-based dairy products using microbial fermentation products' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

DELICIOUS proposes a novel production technology to create affordable, tasty and safe plant-based dairy analogues (cheese and kefir) with high nutritional value, by combining microbial products with plant-based raw materials. The project has the ambition to accelerate the dietary shift, acting like a paradigm for the whole plant-based food sector. DELICIOUS contributes to a better nutrition for everybody by developing products with high protein content, rich in vitamins, fibres and probiotics. The project aims also to decrease the environmental footprint of food industry not only by replacing conventional dairy products in peoples’ diets but also by introducing microbial products which acquire less fresh water, less land use and inexpensive residual raw materials. Having as starting point the perceptions of culinary experts (chefs), the project will improve the sensory characteristics of the current, commercial plant-based products in order to improve their placement in the market. To that end, we will use tailor-made microbial fat, produced via precision fermentation, yeast biomass and fibre-producing microbial strains to achieve the desired organoleptic properties without additives, artificial flavours and avoiding ultra-processing methodologies. To accelerate the commercialisation of the developed products, DELICIOUS will perform various analyses and evaluations: Safety assessments, nutrition simulations, consumers testing and technoeconomic evaluation of the processes combined with behavioural economics to define the profit and price margins for such products. Capitalising on the great capacity and experience of the consortium on High Throughput methodologies, the project has also the great ambition to empower fermentation industry with a bioinformatic tool to predi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Recovery and Use of Nutrients, Energy and Organic Matter from Animal Waste' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The ReUseWaste network will i) provide new ideas and systems that lead to a major rethink in the current, established animal waste management systems, ii) train a group of 13 young researchers in developing new technologies for socially and environmentally sustainable utilisation of the valuable organic matter and nutrient ressources in animal waste and iii) provide companies with both improved and new technologies to produce bioenergy, ”green” bio-fertilisers and improved soil, water and air quality.Global livestock production is increasing rapidly, because of the increasing quest for animal protein by the increasing human population. Apart from the increases in livestock number, there are also major changes in the systems of livestock production. The increases in number and changes in systems have led to major concerns about the sustainability of these developments, especially from the points of view of animal and human health, animal welfare and environmental soundness.Evidently it is necessary for the agricultural livestock industry to develop new environmental technologies to meet global challenges related to environmental impact and sustainability. The industry needs to improve management and utilisation of organic matter and nutrient resources in animal wastes, in order to reduce gaseous emissions of greenhouse gases, ammonia and odor, and to improve energy output and limit the impact on soil and water quality.This multi-site and multidisciplinary ITN provides a unique opportunity for young researchers to obtain the knowledge and skills needed to develop and utilise new technologies for a socially and environmentally responsible management of animal wastes. The ReUseWaste network brings together major EU research groups from leading universities and research inst
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Traffic accident causation in Europe', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

The Integrated Safety programme and the eSafety initiative stress that the development of ITS must be preceded by a scientific accident analysis encompassing two main issues:-The assessment of the most promosing solutions that can assist any road users in a normal or in an emergency situation or, as a last resort, mitigate the violence of crashes and protect vehicle occupants, pedestrians and two-wheelers.- The continuous updating of causes of road accidents and injuries.The objective of TRACE is to provide the scientific community, the stakeholders, the suppliers and the public with an overview of the road accident causation issues in Europe based on the analysis of any and all current available databases which include accident, injury, insurance, medical and exposure data (including driver behaviour in normal driving conditions). The idea is to identify, characterise and quantify the nature of risk factors, groups at risk, specific conflict driving situations & accident situations; it will help to estimate the safety benefits of a selection of technology-based safety functions.Outcomes are essentially reports. Consequently, TRACE is divided into 3 series of workpackages (+ management): OPERATIONAL WP's (Road Users - Types of driving & accident situations, risk factors - Evaluation of the effectivness of safety functions in terms of expected (or observed) accidents avoided and lives saved): three different research angles for the definition and the characterisation of accident causation factors and the evaluation of the benefits of safety functions.METHODOLOGIES WP's (Analysis of Human Factors - Statistical Methods - Determination of Safety Functions): improvement of the methods presently used in accident analysis and transfer of these improvements to the operational w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Open Model For Network-wide Heterogeneous Intersection-based Transport Management' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Traffic managers in Europe face the problem of protecting their investments in telematics infrastructure. Using new applications or even introducing new features to existing systems very frequently forces traffic authorities to make - once more - new investments and replace legacy infrastructure, in many cases while it is still fully operational. OMNI will address this problem by facilitating the re-use of legacy infrastructure by new transport telematics applications. To that end, the project will develop a network-wide, intersection-driven transport management model. The model will act as an intermediate layer that isolates the actual network infrastructure from the applications that are using it. The project will model the existing components in the network considering both their physical characteristics and their functionality. The model will present standard interfaces to the objects of the network, allowing the integration of advanced telematics applications or new devices in a pre-existing network infrastructure. The model will be implemented in the form of two prototypes composed by a set of technical specifications and a software product for exploitation.Fig. 1: OMNI Model.The project will also involve research activities in a number of transport telematics application areas (advanced traffic control systems, automatic incident detection and end user information via the WWW) as well as video-based sensors for surveillance and traffic management. This will allow, on the one hand, achieving additional performance in these application areas and, on the other hand, using these telematics applications and devices as test cases to evaluate the performance of the OMNI model. The final prototype will be evaluated in four pilot sites. The different traffic infrastructur
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Moduli, Algebraic Cycles, and Invariants'.

assistant: **Innovation**

Algebraic geometry is the study of varieties -- the zero sets of polynomial equations in several variables. The subject has a central role in mathematics with connections to number theory, representation theory, and topology. Moduli questions in algebraic geometry concern the behavior of varieties as the coefficients of the defining polynomials vary. At the end of the 20th century, several basic links between the algebraic geometry of moduli spaces and path integrals in quantum field theory were made. The virtual fundamental class plays an essential role in these connections. I propose to study the algebraic cycle theory of basic moduli spaces. The guiding questions are: What are the most important cycles? What is the structure of the algebra of cycles? How can the classes of geometric loci be expressed? The virtual fundamental class and the associated invariants often control the answers. A combination of virtual localization, degeneration, and R-matrix methods together with new ideas from log geometry will be used in the study.Most of the basic moduli spaces in algebraic geometry related to varieties of dimension at most 3 -- including the moduli of curves, the moduli of maps, the moduli of surfaces, and the moduli of sheaves on 3-folds -- will be considered. The current state of the study of the algebraic cycle theory in these cases varies from rather advanced (for the moduli of curves) to much less so (for the moduli of surfaces). There is a range of rich open questions which I will attack: Pixton's conjectures for the moduli of curves, the structure of the ring of Noether-Lefschetz loci for the moduli of K3 surfaces, the holomorphic anomaly equation in Gromov-Witten theory, and conjectures governing descendents for the moduli of sheaves. The dimension 3 restriction
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The evolution and regulation of major transitions in sexual systems: new insights from the brown algae' (TETHYS) targeting Horizon 2020.

assistant: **Abstract**

Sexual reproduction is a pervasive phenomenon that produces new genetic combinations in nearly all eukaryotic lineages. Whilst the core processes that define meiotic sex (meiosis and syngamy) are universal, sex determination systems are not evolutionary conserved but are bewilderingly diverse and have had rapid turnover rates during evolution. Transitions among sex determination systems have profound evolutionary and ecological consequences, but our understanding of the mechanisms, ultimate causes, and the consequences of transitions is still surprisingly incomplete. The goal of the Tethys project is to exploit the exceptional richness of sexual features of the brown algae to gain novel insights into the functional bases and ultimate forces associated with transitions between sexual systems, and their impact on the evolution of this important group of eukaryotes. First, we will exploit the amenability of model brown algae to genetic and genomic approaches to uncover the mechanisms and evolutionary forces driving switches between sexual systems across this group. Secondly, we will investigate the regulation and evolution of the genes involved in sexual reproduction in the context of sexual system transitions, by delineating a comprehensive transcriptional and chromatin state roadmap across key brown algal species. Finally, we will examine patterns of correlated evolution between sexual, functional and genomic traits and incorporate ecological information in order to link ecological factors to reproductive transitions and evaluate their consequences on genome structure and species diversification. Collectively, these multilevel analyses will help answer long-standing evolutionary questions about the diversity and turnover of sex determining systems in eukaryotes, but will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Development of novel digital radiography technology; to facilitate the 'traditionally less research intensive inspection industry sector' change from manual film radiography to automated digital' (FILMFREE).

assistant: **Innovation**

The objectives of the FilmFree project are to make a number of technological advances that will take the digital industrial radiography sector into a new era to effectively replace film as the detecting media. SME's will play the major role in this devel opment and as a result they will make significant commercial gains and growth from the digital radiography market place both within Europe (estimated at 400million Euros annually) and globally (estimated at between 1bn and 1.25bn Euros pa). Medical digi tal radiography is totally unsuitable for industrial use because it cannot operate at the X-Ray energies required to examine engineering materials and metals, nor can it attain the image quality required to find the defects that could ultimately lead to the catastrophic failure of a safety critical component in service. The lower technology NDT (Non Destructive Testing) service inspection companies, are mainly SME's supplying labour intensive inspection services at low margins to traditional industries (e.g. engineering fabrication industry and the rail industry). There are about 2000 of these companies in Europe and they will benefit from the technology advances made in FilmFree by being able to upgrade their services to include digital radiography an d thereby gain access to higher value added sectors such as the petrochemical and oil & gas markets. Similarly the European higher technology digital radiographic equipment suppliers (SME's) will gain a competitive advantage over the small number of Large Enterprise companies that dominate the global market from the USA and Japan. An estimated 10,000 industrial radiographers are exposed to a high risk of radiation within Europe. FilmFree will significantly reduce the risks faced for the majority rad iographers. Also a mini
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Building the information society' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

Specific Objectives1. Develop, test and build consensus on a methodology for data gathering, monitoring and benchmarking the progress of eEurope+ in the CC13;2. Analyse the emerging policy issues with regard to cyber security, in particular with regard to privacy and identity and by exploiting the research finding of EPSO (see project 19);3. Explore the feasibility of a forward looking IST observatory integrating the research findings on e-commerce, e-society and cyber security.Planned DeliverablesSpecific deliverables to DGs:Workshops and their proceedings;Research Reports;Publications.As a result of the research:Advances in technological progress in relevant areas;Advice on long-term policy issues to policy-makers;Promotion of awareness in related industry sectors;Helping political acceptance of standardisation processes.Summary of deliverables made by: 31/12/2001Report to the European Parliaments ITRE Committee on Future Bottlenecks in the Information Society.Report to DG INFSO as a European Commission contribution to the G8 Digital Opportunities Task Force (Dot. Force) on The Digital Divide ¡V A Research Perspective;Organising and managing the ICT Enlargement Panel, preparation of the report on its findings in the context of the Enlargement Futures Project & presentation at the Bled (Slovenia) international conference.Output Indicators and ImpactScientific Outputs: 2 scientific presentations per sub-cluster and 3 scientific publications are foreseen.Impact:A significant contribution to the implementation of eEurope+ and to prospective work on the development of the information society in pre-accession countries;Contribution to policy development on the societal aspects of the information society, including equity effects and social cohesion, info-ethics, mobility an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Engineering ground-state pair interactions by Rydberg Optical Feshbach Resonance Schemes' in the context of a Horizon 2020 call.

assistant: **Objectives**

Quantum simulation is a highly multidisciplinary new field, which, by providing methods for simulating exponentially hard computational problems, forms the basis for the exploration of highly innovative scientific and technological problems. Laser control of atomic and molecular states in the sub-microK regime facilitates the quantum optical approach to quantum simulation, by offering tools for creating new quantum states and for manipulating interparticle interactions, so far on the sub-nm and the microm length scales. This proposal will contribute to this rapidly developing field by introducing a novel all-optical concept suitable for engineering long-range interactions between ground-state atom-atom and atom-ion pairs on a the yet unexplored length scale of ~50-200 nanometers. Key role in this novel technique will be played by bound molecular states formed by a Rydberg-atom and ground-state particles. Since the recent experimental demonstration of the first Rydberg-molecules with neutral atoms, these exotic molecular states have been the subject of intense investigation. The present proposal will investigate the existence of new types of Rydberg-bound states and will provide a general technique for Rydberg-based interaction manipulation. These techniques will serve as a basis for the investigation of novel quantum many-body states in the field of cold gases of neutral atoms and atom-ion mixtures. The complementary experience of the applicant in quantum optics, in particular in laser control of quantum-states of ground-state and Rydberg-excited atoms, and of the host group in many-body physics and laser-induced collisions will allow them to carry out the outlined ambitious research programme. The unique combination of expertise of the host group and of the candidate a