RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'SUstainable Management in EXtractive industries' (SUMEX), addressing dissemination and exploitation.

assistant: **Impact**

In order to foster more, but sustainable mineral production in the EU, SUMEX (SUstainable Management in EXtractive industries) will establish a sustainability framework for the extractive industry in Europe. It does so by considering the Sustainable Development Goals, the European Green Deal, as well as EU Social License to Operate considerations and will involve stakeholders from industry, government, academia and civil society backgrounds from all across the EU. This framework is then applied across the extractive value chain to analyse the mineral, as well as relevant economic, environmental and social policy frameworks of the EU, member states and selected regions along five focus areas - socio-economic and environmental impact assessments, land use planning, health and safety, reporting official statistics and permitting processes/policy integration-to find, or build, where needed, good practices or tools for an open access toolkit, which will be embedded in a broader Community of Practise (CoP) and which forms the basis for capacity building. This CoP will consider relevant stakeholder groups, with a focus on permitting authorities, across the EU, providing a digital platform and using a series of workshops and webinars.In SUMEX, the experience from other projects like MINGUIDE, MINLAND, MIREU, STRADE builds a powerful foundation for addressing the challenge of how best to implement sustainability considerations into the whole raw materials value chain.What makes SUMEX stand out, is that a) it involves Andalusia as a regional partner to act as 1) a test case and 2) to involve other regions, i.e. those represented in MIREU and the OECD Mining Regions and Cities Initiative, to participate in SUMEX; as well as having access to the informal network of mining authoriti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Sex differences in BNST prepronociceptin-expressing neurons in modulating chronic stress-induced depressive-like behaviour in mice' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Major Depressive Disorder (MDD) is a highly prevalent and disabling condition experienced by ~6% of the population worldwide. Interestingly, women are twice as likely as men to suffer from MDD, and the specific mechanisms contributing to such difference are only starting to be elucidated. Chronic mild stress has been shown to reproduce in rodents some of the main traits of MDD, such as anhedonia or anxiety-like behaviour. Chronic stress has been shown to interfere with prepronociceptin (Pnoc) expression in the anterior BNST (amBNST) in rodents. Interestingly, it has been established a functional antagonistic role of Pnoc neurons over corticotropin-releasing hormone (CRH)-expressing neurons, which mediate the stress response in mammals. Moreover, amBNSTPnoc neurons have been shown to support rapid arousal responses toward motivationally salient stimuli in mice. Preliminary data has demonstrated sex differences in amBNSTPnoc distribution across compartments, indicating possible sex-dependent effects of stress on amBNSTPnoc function. We aim to explore sex differences in amBNSTPnoc neurons in rapid arousal responses upon sucrose presentation and its relationship with chronic stress-driven anhedonia. To that end, rapid arousal responses in male and female mice will be studied after chronic stress in mice, and related to anhedonic-like behaviour, and Pnoc and CRH expression in compartments of the BNST. To further understand the effects of chronic stress in Pnoc neurons, calcium transients using 2-photon calcium imaging in amBNSTPnoc neurons will be studied before and after chronic stress. Chemogenetic activation of amBNSTPnoc after stress will be used to functionally test that low Pnoc expression drives hypoarousal states related to anhedonic behavior. The proposal aims to el
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Fractal-generated fluid flows: new flow concepts, technological innovation and fundamentals'.

assistant: **Objectives**

The unprecedented requirements set by thedramatically evolving energy, environmental and climatic constraintsmean that industry needs new turbulent and vortical flow concepts fornew flow-technology solutions. The full potential and economic impactof radically new industrial flow concepts can only be realised with astep change (i) in the ways we generate and condition turbulent andvortical flows and (ii) in our understanding of turbulent flowdynamics and the consequent new predictive approaches.Fractal/multiscale-generated turbulent and vortical flows are a newfamily of flow concepts which I have recently pioneered and whichhold the following double promise:(1) as the basis for a raft of conceptually new technological flowsolutions which can widely set entirely new industrial standards: thisproposal focuses on energy-efficient yet effective mixing devices;low-power highly-enhanced heat exchangers; high-performance wings forUAVs, cars, wind turbines; and realistic wind-field designtechnologies for wind tunnel tests of tall structures such assupertall skyscrapers and wind turbines.(2) As the key new family of turbulent flows which will allowhitherto impossible breakthroughs in our theory and modelling of fluidturbulence.I propose to realise this double promise by a combinedexperimental-computational approach which will use cutting edge HighPerformance Computing (HPC) and high-fidelity simulations based on anew code which combines academic accuracy with industrial versatilityand which is specifically designed to perform very efficient massivelyparallel computations on HPC systems. I will run these simulations intandem with a complementary wide range of wind tunnel, water channeland other laboratory measurements in a two-way interaction betweenlaboratory and computer experim
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'From pebbles to planets: towards new horizons in the formation of planets' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The goal of this ERC Starting Grant proposal is to make significant advances in our understanding of how planetesimals and gas giant planets form. I propose an ambitious research programme dedicated to answering three key questions at the frontier of planet formation theory: - How do mm-sized particles grow past the bouncing barrier? - What is the Initial Mass Function of planetesimals? - How do the cores of gas giants form and evolve?} I will address these questions using a combination of novel ideas and computer simulations to model three critical stages of planet formation: 1) the growth of pebbles into rocks and boulders by coagulation and vapour condensation, 2) the gravitational collapse of clumps of rocks and boulders into planetesimals with an array of sizes, and 3) the long term growth of planetesimals as they grow to become cores of gas giants by accreting pebbles embedded in the gas. These investigations will form an important theoretical foundation for understanding the next generation of observations of protoplanetary disc pebbles, planetesimal belts, and planetary systems. The self-consistent models for the formation of planets resulting from this proposal will shed light on the spatial distribution of pebbles in gas discs around young stars (observable with the ALMA telescopes), on the initial state of planetesimal belts (crucial for understanding the evolution of debris discs observable with JWST and the asteroid and Kuiper belts), and on the formation and evolution of the wealth of exoplanetary systems detected in the near future (by astrometry with the Gaia satellite, by ground-based radial velocity surveys, and by direct imaging with E-ELT).""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Conservation and Divergence of Tissue-Specific Transcriptional Regulation' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Vertebrates contain hundreds of different cell types which maintain phenotypic identity by a combination of epigenetic programming and genomic regulation. Systems biology approaches are now used in a number of laboratories to determine how transcription factors and chromatin marks pattern the human genome. Despite high conservation of the cellular and molecular function of many mammalian transcription factors, our recent experiments in matched mouse and human tissues indicates that most transcription factor binding events to DNA are very poorly conserved. A hypothesis that could account for this apparent divergence is that the larger regional pattern of transcription factor binding may be conserved. To test this, (1) we are characterizing the global transcriptional profile, chromatin state, and complete genomic occupancy of a set of tissue-specific transcription factors in hepatocytes of strategically chosen mammals; (2) to further identify the precise mechanistic contribution of cis and trans effects, we are comparing transcription factor binding at homologous regions of human and mouse DNA in a mouse line that carries human chromosome 21. Together, these projects will provide insight into the general principles of how transcriptional networks are evolutionarily conserved to regulate cell fate specification and function using a clinically important cell type as a model.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Opening Romanticism: Reimagining Romantic Drama for New Audiences' (OpeRaNew), addressing dissemination and exploitation.

assistant: **Impact**

The substantial bibliography devoted to the work of Frances Burney (1757-1840) has confirmed her stature as an author, but it has left the dramatic works that she wrote during her years at the Court of George III almost untouched. The long-delayed publication of these plays has prevented critics from addressing them. For the few scholars who have dealt with them, these texts remain devoid of dramatic qualities. I posit that this quartet of tragedies prompts our critical thinking in terms of such present-day practices and policies as gender relations, body politics, agency: the plays raise many provocative questions, and our current complex juncture seems an especially apt moment to grant them a long-overdue audience as well as a stage. Burney’s speaking bodies—particularly the female ones—unmask and debunk the fraught relationship of the individual with social and state apparatuses, social forces and techniques of disciplining, whose coercions become dangerously naturalised. OpeRaNew aims to restore to Burney’s small dramatic corpus the cultural depth that has been lost over time. By using digital methods alongside literary analysis, the project constructs an expanding multimedia ecology for Burney’s plays—a capacious mediascape that aspires to reproduce, through contemporary tools and channels of communication, the Romantic theatre experience. The action’s core agenda—whose dynamic conversations are evoked by the verb ‘to open’ in the project title—advocates the engagement with an interested public beyond scholarly communities. The project not only sheds light on the overlooked dramatic works of a highly versatile Romantic woman author, but it shows the perspicacity and research potential of positioning—precisely at a time of enormous paradigmatic shifts in research co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Centre of Excellence for the Technologies of Gene and Cell Therapy' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Scientific discoveries on mechanisms of biomedical processes and invention of technologies to repair disease-related genes or destroy cancer cells represent the foundation of an important pillar of personalized medicine. The new Centre of Excellence for the Technologies of Gene and Cell Therapy (CTGCT) will be the first Centre of Excellence in biomedicine in Slovenia and unique with an approach combining mammalian cell synthetic biology and immunology to develop novel technologies for the development of GCTs and cancer immunotherapy in the EU and beyond. The aim of CTGCT is to become one of the leaders in the interdisciplinary breakthrough science technologies for GCT and a model for international research excellence, industrial collaboration and public engagement.CTGCT will gain a competitive edge based on the vertical integration of the technologies for whose further development the foundations have been laid at the National Institute of Chemistry (SI), and with support of expertise and knowledge of the advanced partners University College London (UK), University Medical Centre Utrecht (NL), Charité – Universitätsmedizin Berlin (DE) and Technical University Dresden (DE). Supported by the involvement of clinicians and patient organizations, CTGCT will enable translation of research achievements into therapeutic applications, primarily neurological and rare genetic diseases and cancer immunotherapy, and establish a capacity to prepare the GMP clinical grade therapeutic reagents, which is currently a bottleneck to effective translation. By bridging gap in translation, CTGCT will facilite high impact of excellent research and innovation on health in Slovenia as well as in the West Balkans, East Europe and beyond. It will strengthen scientific capabilities and long-term co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'MAGnetic nanoparticle based liquid ENergy materials for Thermoelectric device Applications' (MAGENTA).

assistant: **Innovation**

MAGENTA proposes a brand new technological path in thermoelectric materials research for waste-heat recovery applications. The originality of the project is based on the newly discovered thermal-to-electric energy conversion capacity of ionic-liquids and ferrofluids; i.e., colloidal dispersions of magnetic nanoparticles in ionic liquids (IL-FFs). It is an inter-disciplinary and cross-sector R&D project combining concepts and techniques from physics, chemistry and electrochemistry with an active participation from 3 SME and 1 industrial partners implicated in the materials supply-chain, the device design/performance and the market-uptake assessment. Both experimental and theoretical approaches will be employed to build foundational knowledge on novel magneto-thermoelectric phenomena in ferrofluids. Computational simulations will allow ‘bottom-up’ construction of IL-FFs with optimal conditions for harvesting energy. The end-products of MAGENTA, application specific magneto-thermoelectric materials and devices, will provide innovation leadership to European companies in waste-heat recovery industries. The lead-user industries targeted by MAGENTA are automobile and microelectronic sectors, but demonstration-type thermoelectric generators will also be produced for public outreach actions on waste-heat recovery technologies. Through its foundational, interdisciplinary and cross-sector research & innovation actions, the consortium will become a “seed community” for building an innovation ecosystem around the novel magneto-thermoelectric technology, presenting long-term impacts on future renewal energy science and technology from which the society as a whole can benefit. Withal, MAGENTA offers breakthrough thermoelectric materials that are versatile, cost-effective and non-toxi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'High-pressure dynamic viscosity and density behaviour of mixtures representative of some dead altered reservoir oils. measurement and modelling.' in the context of a Fifth Framework call.

assistant: **Objectives**

The viscosity is an important property for the design of transport equipment and for the simulation of production profiles from petroleum reservoirs. For this reason experimental measurements and theoretical studies are necessary. For normal oils only few viscosity measurements have been reported in the open literature but for altered oils there is practically no data at all. In this work, we will study some synthetic mixtures representative of such systems. Firstly, we will study the viscosity of two simple binary mixtures containing light alkanet and a branched alkanet or polycylic naphthenic, from 0.1 to 100MPa, and from 20°C to 90° C.Secondly, we will consider multicomponent systems in order to see the influence of the additive. We will analyse ternary, quaternary and quinarymixtures adding an aromatic and another naphtenic one. It is obvious that when the number of compounds increases the mixture is more representative of real reservoir fluids. The data will be used in order to do a comparative study of the performances of several representative models, such as, the LBC model widely used in petroleum engineering, the self-reference model, and the very recent f-theory and free volume models. This study will be very useful because the oil industry needs accurate and reliable viscosity models applicable to wide ranges of temperature, pressure and composition in order to predict the viscosity of the reservoirs for the accurate simulation of the production profile from an oil reservoir. This project will give me the possibility to know about a new subject: experimental studies, modelling and simulation of petroleum fluids. This experience would very useful for me because from a professional point of view it opens future perspectives in research and development in a univ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Direct Visualization of Light-Driven Atomic-Scale Carrier Dynamics in Space and Time' in the context of a Horizon 2020 call.

assistant: **Objectives**

Electronics is rapidly speeding up. Ultimately, miniaturization will reach atomic dimensions and the switching speed will reach optical frequencies. This ultimate regime of lightwave electronics, where atomic-scale charges are controlled by few-cycle laser fields, holds promise to advance information processing technology from today’s microwave frequencies to the thousand times faster regime of optical light fields. All materials, including dielectrics, semiconductors and molecular crystals, react to such field oscillations with an intricate interplay between atomic-scale charge displacements (polarizations)  and collective carrier motion on the nanometer scale (currents). This entanglement provides a rich set of potential mechanisms for switching and control. However, our ability to eventually realize lightwave electronics, or even to make first steps, will critically depend on our ability to actually measure electronic motion in the relevant environment: within/around atoms. The most fundamental approach would be a direct visualization in space and time. This project, if realized, will offer that: a spatiotemporal recording of electronic motion with sub-atomic spatial resolution and sub-optical-cycle time resolution, i.e. picometers and few-femtoseconds/attoseconds. Drawing on our unique combination of expertise covering electron diffraction and few-cycle laser optics likewise, we will replace the photon pulses of conventional attosecond spectroscopy with freely propagating single-electron pulses at picometer de Broglie wavelength, compressed in time by sculpted laser fields. Stroboscopic diffraction/microscopy will provide, after playback of the image sequence, a direct visualization of fundamental electronic activity in space and time. Profound study of atomic-scale