RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Intelligent 3D geometry reconstruction using dynamic and evolution-based techniques' (ISIS), addressing dissemination and exploitation.

assistant: **Impact**

The reconstruction of 3D shapes from unorganized point cloud data is a challenging problem, which has recently attracted much interest in various branches of applied geometry, such as computer vision, computational geometry, computer aided design and computer graphics. This is due to the availability of new and powerful 3D scanning technology, such as optical scanners and CT (computer tomography) equipment. Depending on the application, various techniques for solving this problem have been proposed (and will be analyzed in Activity 1 of this project): Level set techniques are used in medical applications and image processing. The methods developed in Computer Graphics and Computational geometry rely mainly on triangular meshes. Methods for generating full NURBS models (Non-Uniform Rational B-Splines, the universally accepted standard in Computer Aided Design) have been investigated in Computer Aided Geometric Design. The planned project aims at developing a unifying framework, by treating the different techniques as dynamic (evolution) processes (Activity 2 of the project). Many non-linear optimization techniques (such as Newton-type methods used for surface fitting) can be seen to define evolution processes. Consequently, it seems to be natural to study them within a dynamic framework, where a (possibly self-organizing) model evolves towards a target shape (such as an 'active contour model' in computer vision). We expect that this viewpoint improves the global convergence of the nonlinear methods. It will be helpful for generating hybrid models, which combine standard geometries (simple surfaces such as natural quadrics) with free-form geometries (NURBS surfaces or triangular meshes). The use of such models (which may combine different representations of an object) wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Safe and efficient storage of ammonia within ships' (NH3CRAFT), addressing dissemination and exploitation.

assistant: **Impact**

NH3CRAFT aims at fully designing, engineering, developing and demonstrating a next generation sustainable, commercially attractive and safe technology for high-quantity on-board storage of NH3 as marine fuel. Two innovative modular and scalable steel and composite storage tank configurations for 1,000 m3 liquid NH3 at 10 bar and the corresponding auxiliary systems will be installed on a 31,000 Deadweight Tonnage (DWT) multi-purpose vessel. The exact vessel has been designated and provided by a participating major ship management company Additionally, five different types of vessels and corresponding fuel-storage tank concept adaptations will be studied and documented: a SSS bulk carrier, a tanker and a container ocean going vessels, a typical RoPax ferry, and a small Inland Waterways Transportation passenger vessel.An innovative digital platform will integrate all core simulations and models through digital interfaces and will develop an engineering system matrix and specifications for the fuel storage, supply, and piping, monitoring and venting subsystems.Safety and risk assessment for all vessels will lead to the development of safety guidelines and classification rules. NH3CRAFT will showcase the entire NH3 supply chain in order to increase confidence in its use and promote its uptake. LCA and techno-economic evaluation will prove the sustainability and will support further exploitation and commercialization of the innovative solutions.The vision is to pioneer the reduction of GHG emissions by at least 50% by 2050 compared to 2008 and the eventual “elimination of total GHG emissions and air pollution” from shipping (SRIA for ZEWT goals) remaining consistent with the Paris Agreement. NH3CRAFT aspires to help Europe serve societal needs, maintain global maritime leader
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'The Upgrade of the Institut Laue-Langevin (ILL)'.

assistant: **Objectives**

Founded in 1967, the Institut Laue-Langevin (ILL) is an international research centre at the leading edge of neutron science and technology. As a central facility, the ILL provides access to instruments that use low-energy neutrons of unequalled quality and breadth to a community of many thousands of researchers throughout Europe and beyond. The ILL has occupied this leading position for 35 years. In order to keep the ILL at the forefront of neutron science and to provide the best possible experimental facilities and support to its European users over the next two decades, the Institute needs to modernise its infrastructure and instrument suite. This is the scope of the proposed ILL20/20 upgrade programme, which can be summarised as follows: (i) improving neutron moderators and delivery systems; (ii) planning and prototyping new instruments and neutron technologies; (iii) strengthening the links with the European Synchrotron Radiation Facility (ESRF), creating partnerships for science and joint scientific facilities accessible to ILL and ESRF users; (iv) developing the site shared by the ILL, the European Molecular Biology Laboratory (EMBL) and the ESRF. This proposal aims at optimising the preparatory phase of this ambitious programme. The preparation of the upgrade will involve: (i) a benchmarking to enable a strategic decision to be taken on whether or not the ILL should focus on cold instruments ; (ii) feasibility studies, on challenging technical projects to renew the ILL's neutron moderators and delivery facilities, and on neutron scattering technologies; (iii) preparing the framework for a Partnership for Soft Condensed Matter; (iv) planning the development of the ILL/EMBL/ESRF site, including the resolution of the administrative issues.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'CrItical RAw materials extraction in enviroNmentally protected areas' (CIRAN) targeting Horizon Europe.

assistant: **Abstract**

CIRAN will develop, test and validate processes to arrive at systemic policy-making, balancing environmental protection and societal needs for accessing critical raw materials (CRMs). This will be achieved through: 1) streamlined permitting procedures in environmentally protected areas; 2) modern policies and social contract frameworks that reconcile the protection of environmentally sensitive areas and domestic sourcing of CRMs in the EU; and 3) the development of a community of practice to support the uptake of the CIRAN recommendation and that will remain active after the project funding period.CIRAN proposes a logical framework that justifies extraction on the basis of a system-oriented assessment and the co-creation of knowledge (i.e. tested and validated by communities located in or nearby environmentally protected areas). It will create novel social contract models identifying rights, obligations and responsibilities of governments (national/regional), communities and mine operators, capable of dealing with transformations and challenges due to climate change.As a distinctive feature, CIRAN brings together 25 external experts on the environmental, political, social, economic, and technological factors that will shape the energy transition responses and the demand for CRMs. These experts, organised in four Expert Groups (EGs), will work with the Consortium, conveying insights on policy-making and -implementation, economic drivers, technologies, mining, local governance, social capital, nature conservation and biodiversity. The EGs will actively engage in CIRAN through synergetic processes combining analysis and deliberation, and participation in project workshops and structured consultations (e.g., focus groups, foresight analysis).The Consortium is geared to deve
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Epigenetic and genome stability: non coding RNA-mediated chromatin modifications in S. cerevisiae' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Our project is to understand the role of non coding (nc)RNA in the regulation of epigenetic landscape and gene expression. RNA interference pathway is absent in the budding yeast but recent works from our laboratory showed the existence of an original ncRNA-dependent pathway that controls gene expression in S. cerevisiae. We characterized a cryptic unstable ncRNA mediating the transcriptional silencing of the transposon Ty1 through histone methylation. Furthermore, unpublished data suggest the existence of subtelomeric ncRNAs that might control telomere metabolism and promoter-associated ncRNAs that mediate repressive epigenetic marks. We propose that a class of unstable ncRNA mediates genome expression and fluidity through histone modifications. Following 2 directions, our aim is to systematically identify these ncRNAs (A) and further characterize their regulatory mechanisms (B). (A) First, we aim to identify the regulatory ncRNAs by performing genome-wide approaches in strains accumulating these regulatory ncRNAs. We envisage developing protocols to analyze the cryptic transcriptome using deep sequencing technologies. (B) Second, we will further characterize the previously identified regulatory ncRNAs controlling repetitive regions (Ty1 transposon and telomeric repeats) but also gene expression. Through a range of experimental procedures from living cell biology (Fluorescence Immuno Hybridization), biochemical approaches (RNA-TRAP) and genetic, we will determine the dynamics of the regulatory ncRNA within the cell, the associated proteins that regulate their activities and the chromatin defects resulting from their expression. Our aim is to extensively describe the RNAi-like regulation in S. cerevisiae, that we anticipate to be broadly conserved in other eukaryotes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Safety and Mobility Optimization via Virtual Environments Lab' (SafeMoVE) targeting Horizon Europe.

assistant: **Abstract**

SafeMoVE addresses critical gaps in road safety assessment methods, particularly as they pertain to mixed traffic scenarios involving connected and automated vehicles, vulnerable road users, and conventional road users. Building on the scientific advancements of SUperSAFE, SafeMoVE aims to validate and commercialize a universal, proactive methodology for traffic safety analysis. Unlike traditional approaches reliant on historical accident data, the proposed framework employs Extreme Value Theory and Surrogate Measures of Safety to analyse road user interactions, enabling predictions of accident risk without requiring prior crash data. The project encompasses four integrated phases: Data Collection (A1): Using stationary cameras, drones, and simulations to gather detailed exposure and interaction data in real-world and virtual environments; Data Analysis (A2): Extracting and analysing trajectories and interactions to compute SMoS, facilitating safety assessments for both existing and future infrastructures; Framework Development (A3): Validating a proactive methodology for accident prediction and road safety assessment in diverse traffic compositions and automation levels; and Exploitation and Market Exploration (A4): Commercializing the validated methodology through spinouts, targeting stakeholders such as car manufacturers, road authorities, and policymakers. SafeMoVE’s innovative framework aligns with the EU’s Vision Zero target to eliminate road fatalities by 2050. Its proactive approach enables timely safety evaluations, mitigating risks before accidents occur. The project introduces scalable solutions for infrastructure and vehicle safety assessments, fostering advancements in traffic safety research, policy, and industry practices. By integrating multidisciplinary
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Open middleware infrastructure initiative for Europe'.

assistant: **Innovation**

The Open Middleware Infrastructure Institute for Europe (OMII-Europe) has been established to provide key software components for building e-Infrastructures within the European Research Area (ERA).The initial focus for OMII-Europe is to facilitate the development and porting of a common set of application level services to a number of major Grid software distributions, and further to develop tighter interoperability between different Grid distributions. This will provide greater application level portability and will thus simplify the use of Grids, especially when those Grids are built on heterogeneous infrastructures. Many of the major Grid software providers such as EGEE, UNICORE, Globus and CROWNgrid are working with OMII-Europe to achieve these goals in a standards-compliant and open-source manner.OMII-Europe will develop and maintain a repository of quality-assured Grid services that have been re-engineered and sourced from existing open source repositories. Central to OMII-Europe is Quality Assurance. All OMII-Europe-endorsed software components will undergo rigorous testing following a quality assurance methodology published by OMII-Europe.OMII-Europe positions itself as an impartial broker for potential users of key middleware platforms providing impartial, unbiased advice and services. In line with this, OMII-Europe will initiate development of a Grid benchmarking methodology and publish results on a number of major Grid distributions. This benchmark suite will be made available to the community and OMII-Europe will encourage community benchmark contributions.The OMII-Europe project brings together 16 partners from Europe, the USA and China in an initial 2-year project involving in excess of 100 staff years of effort and a budget of 4.83 Million Euros. This is
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'European information exchange service between harbour areas'.

assistant: **Objectives**

EIES intend to set up advanced communications between 4 harbour areas (Santander in Spain, Bordeaux and Brest in France, Bremen in Germany), based on the access to an inter-harbour information system providing information on harbour actors and services.Finalisation of the implementation of all the servicesimplementation of the communications serverRealisation of testswell advanced pilotwell advanced evaluationorganisation of MARCOM97Expected Impactawareness and strong involvement of local and regional actor concerning the interest of advanced communications for harboursMain contributions to the programme objectives:Main deliverablesAdvanced communications between harbour areasContribution to the programmeAwareness and strong involvement of local and regional actor concerning the interest of advance communications for harboursTechnical ApproachThe analysis of user requirements led by the users groups of the 4 EIES harbours shows that from a general point of view the EIES harbour users are interested in having access to information on harbour companies and services, in telecooperation, in integration of EDI based on existing standards (Edifact, Odette...) and iny E-mail.Therefore, the EIES system has been designed to provide the user (who is supposed to have a PC operating under Windows 95) with a specific EIES user interface integrating the user's office applications and giving access to the 5 previously defined services. :The Blue Pages service provides multimedia information on harbour companies. Port Entry Guide provides information on harbour services from a map, precise representation of the harbour area.Four kinds of accesses are planned: by ISDN, ATM, Internet for the fixed access and DSRR (Digital Short Range Radio), DECT and INMARSAT for the mobile access.Summar
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Role of the ATP-Binding Cassette Transporter Abcg2 in Cardiac Regeneration', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Cardiac muscle death, without equivalent cardiomyocyte replacement, results in severe deficiencies in cardiac pump function both after myocardial infarction and in those chronic cardiomyopathies where apoptosis is prevalent. For this reason, understanding the molecular events that allow but severely limit cardiac regeneration in heart disease is of fundamental importance and may also hold immense translational potential.The ATP-Binding Cassette Transporter Abcg2 is expressed in various healthy organs and protects, against toxic compounds and their metabolites as well as against hypoxia and oxidative stress, conditions present during ischemic heart injury.  Abcg2 is a common marker of tissue progenitor cells, including the dormant stem cells in adult mouse and human heart. Abcg2 plays a pivotal role in cardiac repair following infarction in mice, which to date has been ascribed to its protection of endothelial cells, the other site of Abcg2 expression in the heart. Its function in cardiac progenitor cells remains to be tested conclusively.With the use of genetically modified mice and fate-mapping techniques, this study will determine the functional role of an ATP-binding cassette transporter, Abcg2, in the clonogenicity of heart-derived progenitor cells in culture and the contribution of cells expressing this protein in new myocyte creation after myocardial infarction. We will: (1) Determine the role of Abcg2 in cardiac progenitor cells’ function, as defined by in vitro studies of clonal growth and its relationship with hyperoxic stress in culture, by disruption of Abcg2 in adult mice or isolated cells. (2) Establish whether conditional disruption of Abcg2 in adult mice influences cardiac function during recovery from experimental myocardial infarction. (3) Define the co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'In vitro model of lympho-hematopoietic differentiation from murine embryonicstem(es) cell. Characterization of lineage specific gene expression and cytokines requirements' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

The development of T and B lymphocytes characterized by a precise sequence of maturatlon steps, some of which defined by the expression of specific cell surface markers. Aim of this research project is to develop a system for the analysis of the molecular and cellular aspects during the early phases of lymphoid development : the first effort will be devoted to the establishment of reproducible system for generating T and/or B lymphocytes from murine embryonic stem cells (ES) in vitro. A combination of varius cytokines and several stromal cell lines known to have a potent lymphohematopoietic promoting activity will be used on these undifferentiated, pluripotent cells, both to elucidate the relative role of these cytokines in lymphoid development and to better understand T cell differentiation Secondly, this system will be used to identify new genes involved in the lymphoid differentiation pathways, using a strategy based on the gene-trap approach.