RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Culture Aware Robots and Environmental Sensor Systems for Elderly Support' to be submitted under Horizon 2020.

assistant: **Abstract**

The groundbreaking objective of CARESSES is to build culturally competent care robots, able to autonomously re-configure their way of acting and speaking, when offering a service, to match the culture, customs and etiquette of the person they are assisting. By designing robots that are more sensitive to the user’s needs, CARESSES’ innovative solution will offer elderly clients a safe, reliable and intuitive system to foster their independence and autonomy, with a greater impact on quality of life, a reduced caregiver burden, and an improved efficiency and efficacy. The need for cultural competence has been deeply investigated in the Nursing literature. However, it has been totally neglected in Robotics. CARESSES stems from the consideration that cultural competence is crucial for care robots as it is for human caregivers. From the user’s perspective, a culturally appropriate behavior is key to improve acceptability; from the commercial perspective, it will open new avenues for marketing robots across different countries. CARESSES will adopt the following approach. First, we will study how to represent cultural models, how to use these models in sensing, planning and acting, and how to acquire them. Second, we will consider three (physically identical) replicas of a commercial robot on the market and integrate cultural models into them, by making them culturally competent. Third, we will test the three robots, customized for three different cultures, in the EU (two cultural groups) and Japan (one cultural group), on a number of elderly volunteers and their informal caregivers. Evaluation will be conducted through quantitative and qualitative investigation.To achieve its groundbreaking objective, CARESSES will involve a multidisciplinary team of EU and Japanese researcher
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Biocementation for railway earthworks'.

assistant: **Concept**

In a number of European countries, old railway transport infrastructure earthworks are suffering from serviceability problems or failures and need continuing and costly maintenance/remediation works. This is becoming a major constraint for railway owners and operators, especially in the light of the increased risk of hazards posed by climate change. The hypothesis of this research is that biocementation (a technique that uses natural biological processes to bind soil grains) is a viable and sustainable technique for improving the structural stability of railway earthworks, and hence, the resilience of the EU’s transport infrastructure. The hypothesis will be tested through the application of the technique on earthwork materials of the UK rail network. After establishing improved microbial systems and processes, the project will involve advanced soil testing. The testing will give high quality data on the hydromechanical properties and behaviour of biocemented soils. Careful consideration will be given to the behaviour of the soil under unsaturated soil conditions (soil voids partially filled with water) which has not been researched. The data will be interpreted by constitutive modelling of the soil behaviour. The model will be implemented to commercial software, giving researchers and engineers a useful predictive tool for the analysis and design of biocemented soils. Having assessed the technique and the durability of the biocementation in the laboratory, a significant advance of this research will be the pilot application of the technique on actual railway assets, made accessible by a major owner and operator of railway infrastructure. This novel technique is proposed to be environmentally superior to conventional grouts (which are toxic) and other common soil stabil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Purposing de novo protein scaffolds for the Heck reaction' (DENOPHECK), addressing dissemination and exploitation.

assistant: **Impact**

The overall aim of this fellowship is to develop an enzymes that catalyses the Heck reaction using de novo proteins. We now live in an age where the consequences of the emissions of greenhouse gases are having observable, detrimental effects on our planet’s ecosystem. Therefore, the need to develop non-toxic, cleaner and lower energy reactions is essential. Palladium(0)-catalysed cross-coupling reactions are a powerful method for generating carbon-carbon and carbon-heteroatom bonds, leading to their extensive use in academia and industry. Among all cross-coupling reactions, it can be argued that the Heck reaction is one of the greenest because the reagents are not prefunctionalised with metals, boron or silicon. Furthermore, it has been demonstrated that the Heck reaction can be performed in water, although truly catalytic examples to date require temperatures up to 140 °C and often more reactive and expensive aryl bromide and aryl iodide reagents. De novo protein design, the selection of an amino-acid sequence that will fold to a desired protein structure, is a newly established field. Successful designs have furnished a diverse range of protein structures. In contrast to most natural proteins, de novo proteins are well understood, have high thermal stability and are characterised to atomic detail. Dr Rhys, under the supervision of Prof Höcker & Prof Weber, proposes to purpose a range of de novo proteins to bind artificial co-factors to develop truly de novo Heckase enzymes. Functional enzymes will be optimised using well-established rational design and directed-evolution techniques.   The development of an optimised Heckase could overcome existing challenges to produce an ambient temperature, stereoselective, water-soluble Heck catalyst.


**Keywords:** de novo protei
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'HPC and Big Data Technologies for Global Systems' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Developing evidence and understanding concerning Global Challenges and their underlying parameters is rapidly becoming a vital challenge for modern societies. Various examples, such as health care, the transition of green technologies or the evolution of the global climate up to hazards and stress tests for the financial sector demonstrate the complexity of the involved systems and underpin their interdisciplinary as well as their globality. This becomes even more obvious if coupled systems are considered: problem statements and their corresponding parameters are dependent on each other, which results in interconnected simulations with a tremendous overall complexity. Although the process for bringing together the different communities has already started within the Centre of Excellence for Global Systems Science (CoeGSS), the importance of assisted decision making by addressing global, multi-dimensional problems is more important than ever. Global decisions with their dependencies cannot be based on incomplete problem assessments or gut feelings anymore, since impacts cannot be foreseen without an accurate problem representation and its systemic evolution. Therefore, HiDALGO bridges that shortcoming by enabling highly accurate simulations, data analytics and data visualisation but also by providing knowledge on how to integrate the various workflows and the corresponding data.


**Keywords:** HPC HPDA Technology Exascale Simulation BigData Analytics
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Research in Nanoelectronics: High-k Materials and High-Mobility-Channel CMOS devices', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

For several decades, silicon semiconductor devices have been scaled down to achieve higher device density and performance. As a result, alternative gate oxides with high dielectric constant (high-k), which can prevent power dissipation resulting from direct quantum mechanical tunneling across the dielectric layer, will replace silicon dioxide which has been used as a gate dielectric in metal-oxide-semiconductor field effect transistors. Deposited hafnium oxide-based insulators are currently the most promising high-k materials for MOS device applications. However, it has been consistently observed that high-k based MOSFETs have problems such as reduced mobility of electronic carriers in the transistor channel, difficulty in setting the threshold voltage (Vth) for CMOS devices, Vth instability, and other device reliability problems. Further improvements require a fundamental understanding of these phenomena.The second aim of this work is the study of Materials for High-Mobility-Channel MOS. Due to their superior properties such as high electron and hole mobility, Ge and III-V materials have been drawing much attention as a high-mobility-channel layer in the future MOS technology. However, there are some major issues that need to be solved to advance the development of high-mobility-channel MOS such as growth of good quality high k dielectric layer with low interface states
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'EXPLORATORY HEAVY-QUARK JET TOMOGRAPHY OF QUARK-GLUON PLASMA AT THE LHC' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The unprecedented center of mass energy available at the Large Hadron Collider (LHC) opens a new window for the exploration of Quark Gluon Plasma (QGP). Jet shape and jet topology measurements will become feasible as a new, differential, and accurate test of the underlying QCD theory and are instrumental in discovering novel effective interactions and phenomena that arise in matter under extreme conditions, allowing the development of precision radiography of strongly interacting plasmas. The project aims at studying the energy loss mechanisms in the Quark Gluon Plasma at the Large Hadron Collider (LHC) with the Compact Muon solenoid (CMS) detector: experimentally differentiate between radiative and collisional energy loss and address the problem of mass dependence of energy loss. The proposed tools for these studies are the heavy-quark tagged jets versus the accompanying light-parton jets, in the channel QQbar+jet. The tagging of these events will be accomplished by identifying, within a particular kinematic region, muon pairs produced in the simultaneous semi-leptonic decay of two heavy mesons. The techniques that will be used is the jet shape analysis. The shape of the energy and particle distribution of both the heavy-quark jet, and the accompanying light parton jet will be analyzed. The jet shape will be mapped both as a function of the cone radius and the transverse momentum distribution of particles inside the jet. This proposed exploratory research is the first of its kind in heavy-ion collisions and constitutes one of the first steps in developing the experimental bases of `jet tomography' of the QGP at the LHC. By taking a leading role, in a novel line of research (jet shape tomography of QGP) through this project, as member of an European institution, Laborat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Photovoltaic cells based on nano-structured CdTe', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Cadmium Telluride (CdTe) is already established as a prominent conventional solar cell semiconductor material due to its energy gap 1.5 eV with an almost perfect match to the solar spectrum. The aim of this research is to study the use of nano-structured CdTe as the absorbing layer in PV solar cells, and to evaluate the performance and industrial potential of these cells for a spread of PV applications, from low cost to high efficiency thermo-sensitive platforms and devices. It would require an investigation of processes for inexpensive fabrication of large periodic arrays of semiconductor nanostructures that will allow for (a) controlled variations in the size and composition of the nanostructures, (b) encapsulation of the semiconductor nanostructures in a rugged host material, (c) flexibility to use a variety of substrate materials, and (d) compatibility with standard silicon fabrication techniques. Additionally, the same CdTe-based PV nano-structures could be used as efficient imaging flat-panel direct-conversion semiconductor detectors for applications in such diverse fields as nuclear medicine, homeland security, astrophysics, and environmental remediation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Scientific Service Support based on GALILEO E5 Receivers' (SX5).

assistant: **Innovation**

GALILEO will offer one dedicated signal which is superior to all other signals that are or will be available in space, namely the broadband signal E5. This signal as well as its sub-carriers E5a and E5b will feature an ultimately low range noise in the centimetre range as well as the lowest multipath error impact ever observed in the history of satellite navigation which can be in the range of a couple of centimetres in benign environments and is by far smaller than the multipath errors on all other signals in all other environments as well.Up to now, much development efforts are put into dual- and multi-frequency GNSS receivers. The scientitifc community actually focuses on this type of device, because it is commonly believed that more than one frequency is needed to get rid of the ionospheric delay error. This, however, it not true. An E5 single-frequency system can also be used for precise positioning in the future leading the way to new and innovative processing strategies based up receiver which can be cheaper than multi-frequency systems.The main motivation for the SX5 project proposal is: (1) The best-possible use of the E5 broadband signal for scientific applications. (2) The provision of full configuration flexibility of a receiver to scientists. (3) The implementation and validation of an application prototype and its demonstration to the scientific user community.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Activating Senior Potential in Ageing Europe' (ASPA).

assistant: **Concept**

The dejuvenation and ageing of Europe's population puts society for some major challenges. The development towards a knowledge-based society requires continues investment in new knowledge and skills. Given the ageing of the population and low fertility rates it also requires high(er) participation rates of females and people over fifty. So far, employers’ and governments’ policies have focused on human capital investments for the younger age categories and have stimulated older workers to retire at a relatively early age, in stead of investing in sustainable workers throughout the life course.   This proposal aims for an ambitious, exhaustive examination of the forces and mechanisms behind employers’ and governments’ behaviour and the resulting societal arrangements. To that aim it will use large-scale surveys for the analyses of employers’ behaviour and desk research and interviews to map government behaviour. Statistical and focus group analyses will be used to get insight in the participation and activity rates of people between 50 to 70. Next, the project tries to identify good practices at the company level and at the level of (national or local) government policies that contribute to continuous investment in knowledge and skills throughout the life course, resulting in high activity rates for people between 50 and 70.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Identification of hedgehog target genes' (1998-2002).

assistant: **Concept**

Identifying target genes of signaling pathways that operate during embryogenesis is an important step toward understanding how signals govern morphogenesis. I propose to search for targets of Hedgehog signaling in the hope of understanding how Hedgehog controls the formation of segment boundaries in Drosophila embryos. I will also pay attention to Hedgehog targets that might be involved in Wingless degradation, another interest of my host lab. I will apply the degron technology to construct a temperature sensitive allele of cubitus interuptus an essential effector of Hh signaling. RNA extraction after temperature shifts and hybridization onto micro arrays will allow me to uncover manges in transcriptional profile caused by loss of cubitus interuptus function and hence identify physiological target genes that operate at different stages. If the degron method cannot be applied to Drosophila, I will use the inducible expression of two forms of cubitus interuptus (a constitutive repressor and a constitutive activator) to identify targets. In site hybridization will be used to confirm candidate targets and subsequent functional analysis will assess the cell biological function of confirmed targets.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'GENOME-BASED THERAPEUTIC DRUGS FOR DEPRESSION (GENDEP)' (GENDEP), addressing dissemination and exploitation.

assistant: **Impact**

Although there is abundant evidence for efficacy of antidepressants a substantial minority of patients show an unsatisfactory response, and cessation of medication because of adverse effects is common. The choice of what drug to prescribe for optimal response with minimum unwanted effects is largely a matter of taking an educated guess. Pharmacogenetics offers considerable potential to provide tools to aid targeted, rational prescribing. GENDEP has three closely interconnected major themes aimed to address these issues. The first is a large scale multi-centre clinical trial focussed on the prediction of therapeutic response to antidepressants and adverse effects. The second is a set of basic science studies using animal models and in vitro experiments, and the third is a programme of work to address the relevant ethical, social, and legal issues. This project will include an integrative analysis of the results of the transcriptomics and proteomics on the samples from the human, the rodent, and the in vitro studies, in order to identify biomarkers consistently identified across all of these experimental methodologies. This integrated project should lead to validated pharmacogenomic methods for symptom improvement, the prediction of response to psychiatric drug treatment and the reduction of adverse effects. We may also be able to make a beginning on identifying new targets for drug discovery.GENDEP will examine such associated issues as the views of service users regarding consent in human pharmacogenomics studies, a cost-benefit analysis of introducing pharmacogenomic theranostics, and the investigation of the potential impact of a new generation of pharmacogenomically tailored treatments on patients' and consumers' views and attitutdes. A key feature of the entire proj