RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Where does European law draw its authority from? Putting the European legal field back in' (EUROLAWFIELD), addressing dissemination and exploitation.

assistant: **Impact**

EUROLAWFIELD aims at providing a new conceptual framework to address empirically the following enigma: how can EU laws authority resist in a current context in which:- the Union is undergoing an unprecedented legitimacy crisis in which the central role of Law and other non-democratically elected EU actors is particularly criticized,- the cohesion of the EU-specialized legal community is jeopardized by its very success (enlargement of the EU, development of new EU legal domains and sub-fields)The issue is not only theoretically important but also politically relevant since it is widely acknowledged that the European Union has based much of his legitimacy on Law.The existing literature has essentially exemplified the role of social interests in the perennial importance of EU law but it has failed to analyze the very contribution of legal actors.Drawing a new set of concepts imported from the field of international relations studies as well as from the socio-legal one, this proposal intends to overcome this shortcoming.By putting the social and professional structure of the European Legal Field, EUROLAWFIELD intends to shed a new light on how EU laws authority is secured in a European political order that is still deprived of the conventional warrants of State sovereignty.The research strategy will follow two directions.First, it will build on extensive interviews with key Euro-law actors to map the functioning of the European Legal Field. By tracing the careers of particular individuals, it will reveal what sort of connections exists between the various arenas of European law practice.Second, by analyzing the mobilizations of EU lawyers, it will focus on their attempt to build a common professional identity of jurists in the frame of the European integration process.These
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'CONTROLLED RIPENING AND INCREASED STORAGE LIFE OF FRUIT AND VEGETABLES THROUGH ETHYLENE CONTROL' (1994-1998) under Fourth Framework.

assistant: **Objectives**

The international trade in fruit and vegetables is of considerable importance and currently the EU is the biggest world market for these products. The European Union as a whole produces large quantities of fruit and vegetables, especially tomato, apple, citrus grapes and kiwi. However, production is both local and seasonal and thus requires extensive transportation and storage. The loss of quality during prolonged shipment and storage of these perishable commodities represents a major problem to EU fruit and vegetables growers.The onset of ripening predisposes fruit to losses due to advanced senescence and decay through microbial attack. This is especially a problem in so-called climacteric produce in which ripening is controlled by the gaseous plant hormone ethylene. The detrimental effects of endogenously produced ethylene on the acceleration of ripening and senescence is well known. Ethylene causes great losses in commercial horticulture and limits control of endogenous ethylene production food crops by means of the currently available chemical inhibitors (e.g. silver salts, diaminozide compounds) is unacceptable both from an environmental as well as a consumer point of view. Recently, molecular genetic techniques to increase plant performance have been developed. Genetic engineering of food crops aiming to improve the postharvest life is currently applied to a very limited number of cases. However, both laboratory as well as field experiments have showed that this approach is very successful. Extension of these techniques to a more complete range of fruit and vegetables represents a great economical challenge.The proposed research project aims to increase plant quality, in particular the post harvest life of fruit and vegetables, by :- suppression or over-expression
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'To develop blown woodfiber insulating material (EKOVILLA) to rigid thermal insulating panel form' under Fourth Framework.

assistant: **Concept**

Recycling, environmental aspect, ease of handling and rate of production are most important for construction industry to select materials to be used on construction material factories and construction sites. To develop wood fiber insulating material suitable to use easier opens a wide range of new solution. Research is required with the European SME partners and research institution into the parameters, which makes possible to get blown wooden fiber into the rigid form, which saves the insulating properties and into methods for its safe, easy and fast to handle in production and construction sites and enlarge the area of usage of existing wooden fiber products.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'ASP-New Game' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The objective of ASP-New Game is to research, develop and implement a new middleware for ASP/ISPs. The new platform will integrate all the required functionality for running an ASP operation, including new methods, such as Streaming Application, to deliver productivity tools and rich content, secure keying of IP and Digital Rights Management. The proposed ASP-NG project is aimed at providing ASP/ISPs, small, medium, or large enterprises (SMEs and Telecos), with a complete set of features required to run an ASP. The new platform will enable integration of some of the existing technologies, such as Thin Client. Streaming Application enhances the usage of rich media and games through ASP/ISPs it is protected by a unique security key, and makes use of distributed servers, such as those found in Content Delivery/Distribution Networks (CDNs). The main objective of the project is to run 3 successful pilots and complete, based on pilots results, the definition of the ASP-NG product.Work description:The workplan of the project includes four technological workpackages. The main system and software implementation workpackage will begin after a requirement analysis (End Users-ASP/ISP and Clients), design of business-process and design of system's architecture and system's parts. The workpackage for system and software implementation includes a list of tasks required for the development of an integrated middleware platform. This middleware will include all the required elements for small and large sized ASP/ISP. Also included are, an innovative technology, Streaming Application Technique, and new technologies for content protection (Digital Right Management-DRM) and for QoS handling. The other tasks are system integration, database handling, front end-WEB portal, authentication, hel
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Dynamic mechanisms and functional roles of synaptic plasticity in memory', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Activity-dependent plasticity of synaptic transmission together with refinement of neural circuits connectivity are amongst the core mechanisms underlying learning and memory. While there is already extensive knowledge on some of the mechanisms of synaptic plasticity, fundamental questions remain on the dynamics of the underlying molecular events and the functional roles of various forms of synaptic plasticity in information processing, learning and behavior.We previously uncovered basic features of glutamate receptor movements and their role in excitatory synaptic transmission. Our new ground-breaking objectives are: 1) to uncover, in a physiological context, the dynamic mechanisms through which synapses modulate their strength in response to neuronal activity by integrating on different space and time scales the properties of receptor traffic pathways and associated stabilization mechanisms, 2) to use our knowledge and innovative tools to interfere with these trafficking mechanisms in order to decipher the specific roles of different forms of synaptic plasticity in given brain functions and behavioral tasks. For this aim, I lead a team of neurobiologists, physicists and chemists with a collaborative record of accomplishment. We will combine imaging, cellular neurobiology, physiology and behavior to probe the mechanisms and roles of different forms of synaptic plasticity.New in tissue high-resolution imaging combined with innovative molecular reporters and electrophysiology will allow analysis of receptor traffic during short and long-term synaptic plasticity in physiological conditions. We will probe the interplay between activity-dependent changes in synaptic strength and circuit function with new photo-activable modifiers of receptor traffic with an unprecedented ti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Big Data Value ecosystem' (BDVe) targeting Horizon 2020.

assistant: **Abstract**

The mission of BDVe is to support the Big Data Value PPP in realizing a vibrant data-driven EU economy or said in other words, BDVe will support the implementation of the PPP to be a SUCCESS.Behind that mission, there are multiple goals to achieve, which should be taken into full consideration when defining the directions of the PPP. Some of the most challenging ones are: (1) achieving a more competitive landscape of European Big Data providers, leading to bigger market share; (2) creating the context for a more competitive EU industry (transport, manufacturing, public sector, agrifood, media, energy…) in the advent of a data-driven revolution where many traditional players will have to transform their processes and re-think their business if they want to remain completive –or in some cases, just to survive-; (3) ensuring the sustainability of the investments and actions triggered by the PPP.BDVe has broken down those high-level goals into 7 major priorities for the project:• Being accurately informed about most important facts in Big Data so that we have a solid basis to support the decision-making process in the PPP• Supporting the implementation of the Big Data PPP from an operational point of view• Developing a vibrant community around the PPP• Supporting the development of a European network of infrastructures and centers of excellence around Big Data• Setting-up a professional Communications strategy• Setting up a framework that supports the acceleration of data-driven businesses, and• Ensuring the sustainability of the investments and actions triggered by the PPP.The BDVe consortium includes a set of partners that have shown commitment and dedication to the success of the PPP for several years. They have already invested and they have committed to invest along th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Intracellular lipid transport and translocation to the cell surface' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Research objectives and content Lipid translocation to the outer leaflet of the plasma membrane The objective is to determine how phospholipids reach their destination within the cell. In contrast with proteins the final localisation of a phospholipid molecule depends on it's intracellular transport between organelles and it's translocation (or 'flipping') between the two leaflets of the bilayer. The first stage of the project will characterise the translocation of natural lipid by the human multidrug resistance proteins MDR1 and MDR3. Methods already developed in the host laboratory will be used to permeabilize selectively one of the two plasma membrane domains of LLC PK1 cells grown on filters. Addition of liposomes of natural radiolabelled phospholipid in the presence of the appropriate transfer protein to the non-permeabilized surface will make it possible to assay translocation across the plasma membrane to the permeabalized side. This can be achieved by either the use of an appropriate bacterial phospholipase C in a kinetic assay or by using an appropriate transfer protein and a liposome acceptor. Further experiments, in primary cells from knock out mice, will determine the role of phospholipid transfer proteins in intracellular transport in intact cells. Training content (objective, benefit and expected impact) The objective is to do excellent science in one of the leading laboratories in the field of phospholipid traffic in polarised cells. The proposed project provides me with training in molecular biology, cell biology and lipid biochemistry which is necessary for the long-term goal of my research, namely to contribute to the elucidation of how lipids are transported and sorted on route to the plasma membrane and the sites and regulation of synthesis of phosph
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Specific functions of individual Cdc42 and polarity protein variants in cellular processes and glioblastoma progression' to be submitted under Seventh Framework.

assistant: **Abstract**

The Rho-GTPase Cdc42 is a key regulator of the actin and microtubule network, thereby regulating cellular processes like cell polarization and motility or membrane traffic. Two isoforms of Cdc42 exist; one ubiquitously expressed, the other being brain-specific. Most studies have focused on the former and specific functions of the brain-restricted variant remain obscure. Recent observations from Etienne-Manneville’s lab uncover an isoform-specific alteration of Cdc42 expression in glioblastoma, a most invasive type of brain tumour, leading us to investigate the individual functions of each variant. In this project, we will compare the intracellular localization patterns of the two isoforms and investigate the underlying targeting mechanisms. The individual subset of binding partners will be analyzed, as well as how alterations of Cdc42 variants expression may affect membrane protrusion, polarization and motility in normal astrocytes. Results will then be compared to that of reconstituted or RNAi-treated glioblastoma cells, in order to define the consequences of abnormal expression of Cdc42 isoforms in the invasiveness of brain tumour cells. Furthermore, variants of the polarity proteins aPKC and Par6, which were also found to be misregulated in glioblastoma, will be analysed for their individual relevance in the context of migration and polarity. Understanding the regulatory background leading to the high invasiveness of glioblastoma is most important, as single tumour cells commonly infiltrate brain tissue several centimetres away from the main tumour, making a complete surgical clearance impossible. Characterizing “risk factors” in glioblastoma progression, as potentially given by misregulated expression of proteins influencing cell migration and polarity, may furtherm
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Innovative Business Models for a new Integrated Rapid Microbial Pathogen Tester'.

assistant: **Innovation**

DelAgua Water Testing currently retails and distributes water testing equipment and consumables to over 150 countries globally. Our client base includes private, public sector and significant numbers of non-governmental organizations.  DelAgua is researching an innovative, rapid, microbiological pathogen water test for field use in routine monitoring, surveillance and disaster relief situations. This test will identify bacterial species, their viability and numbers present in less than 2 hours.   User feedback has indicated that the device must meet the following criteria:• Simple to use• Portable• Rugged• No need for mains power• Have an automated means of recording and analysing resultsCurrent test equipment offers a choice between rapid absence/ presence indicators with no quantification; or tests which offer quantification and specificity but with significant process time (from 18 hours to several days) for a result. There is real demand for this new rapid test which will have applications globally for the testing of drinking water and more widely irrigation, bathing and recreational waters, and water/wastewater treatment plants under private and public management.Unique features of our new test offer an opportunity to go beyond our current retail and distribution model. We wish to test radically innovative business models which could offer greater value and flexibility to both DelAgua and its customers. We believe a different model could open entirely new markets and impact on the health of millions of people worldwide through the provision of near real time regional water safety monitoring systems, something never before achieved.A European supply chain will be created to manufacture both the hardware and consumables and DelAgua will create R&D facilities and jobs
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'ThermoElectric Coatings by Liquid Thermal Spraying' in the context of a Seventh Framework call.

assistant: **Objectives**

TE-Coat is to develop a strategic European partnership by uniting research activities between a SME and a leading EU university. 8 researchers will be trained with advanced techniques in surface engineering and computational modelling by focusing on real engineering problems. The use of the state-of-the-art modelling approaches will revolutionize the technology development for next generation nanostructured protective coatings with profound impact to surface engineering industry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Development of a toxin screening multi-parameter on-line biochip system' in the context of a Sixth Framework call.

assistant: **Objectives**

Tissue culture of cell lines has the potential to replace animal testing, but for such in-vitro approaches to be successful, new and sensitive methods to detect cellular activities are required. ToxiChip will focus on both the development and promotion of alternative in-vitro testing methods for the monitoring of a vast array of toxins, thus alleviating the current demand for animal sacrifice while also permitting high throughput screening. The primary objective is to develop a eukaryote cell based biochip that will be tailored for dual analysis capability (optical and electrochemical) and will be used as a monitoring tool for examining the effects of toxins on a wide range of cell parameters such as, impedance, changes in morphology, distribution and pH.This technology will help to provide an in-depth knowledge of the various cellular responses that occur as a result of toxicity and will have major beneficial implications in such applications as neurology, cytotoxicity and pharmacology. For example in monitoring the overall toxic effects of not only individual chemicals but also combinations of these chemicals in areas such as environmental analysis of wastewater and in drug development. Another objective of this project is to develop a prokaryote based biochip, solely used for detection of toxins using optical analysis only.A panel of genetically engineered bacterial strains that sensitively report on the presence of toxins that normally affect eukaryotic cells, thus eliminating the need to sacrifice animals for experimentation will be developed. In the envisaged system, these bacteria that are immobilised on the prokaryote cell based biochip, will emit a readily measurable signal (fluorescence, bioluminescence, electrochemical etc.) in the presence of different sets