RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'COmputational Modelling for EXtreme conditions' (COMEX).

assistant: **Innovation**

Pressure is an important thermodynamic variable in order to understand the properties of the materials, even at room pressure, because it allows for a precise control over the interatomic distances and hence the atomic interactions. Moreover, the application of high pressure, many times in combination with high temperatures, allows the synthesis of new phases of materials with completely different properties to those from stable materials at room conditions. New phases of materials may be metastable at room conditions and thus lead to new technological advances.Sesquichalcogenides (A2X3 stoichiometry) have been traditionally studied due to their many interesting applications at high pressure. These interesting properties, together with the search for miniaturization, which includes isolating layers to form 2D mono- or bi-layer systems, have motivated an increased interest to explore the properties of the A2X3 compounds in the nanosize regime as well. In this regime, quantum confinement effects could become dominant thus altering the structural, electronic and optical behaviour when compared with the bulk material. In this context, studies of the properties of many bulk and nanocrystalline sesquichalcogenides are still required since their high pressure and high temperature phases have not yet been fully explored. Thus, the goal of this project is to study, from a theoretical perspective by employing ab-initio calculations, the structural, vibrational, elastic, and electronic properties of sesquichalcogenides under extreme conditions of high pressure and temperature and predict stable and metastable phases of these materials under these extreme conditions. The proposed work will complement experimental studies and will provide basic understanding of the physical-chemical
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Development of immunoaffinity sample pretreatment methods. Application in the analysis of taxol'.

assistant: **Objectives**

Research objectives and content Our aim is to develop immunoaffinity columns to apply in the extraction of various types of samples that contain taxanes. Polyclonal antibodies against taxanes, will be isolated from animal and will be immobilised on an appropriate support. The selectivity of the immobilised antibodies on the recognition of taxanes will benefit on the selective isolation of the compounds of interest from complex extracts. Another advantage of the proposed method is the sensitivity of the immunoassay. Samples having low taxane content could be extracted without the problems phased by conventional SPE. and subsequently analysed by HPLC-diode array with the methods we have already developed. HPLC analysis could be simplified and probably prove more informative since numerous contaminants would already be discarded during the immunoassay. By combining the selectivity of the immunoassay with the chromatographic results (retention and spectral data) the confirmation of the nature of the analytes would be easier, thus reducing the need of using LC-MS analysis. Training content (objective, benefit and expected impact) The main benefit obtained from the requested training will be the involvement of the applicant with a new discipline and methodology. Apart from that, the initiation of a new project in the Laboratory of Analytical Chemistry AUTH will profit to the institutions as well. A new technique will be established in the laboratory and the transfer of expertise and knowledge on this topic from the co-operative laboratories will benefit not only to the applicant but also to the host institution. The requested project can work as the first step in a future closer collaboration of the interrelated laboratories. Links with industry / industrial relevance (22) Th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Near-term predictability of net primary production in the Atlantic Ocean' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The main goal of this research project is the improvement of near-term (i.e. seasonal to decadal) predictions of Net Primary Production (NPP) in the Atlantic Ocean. NPP is the rate of production of phytoplankton biomass, the primary source of food for marine animal life and thus a fundamental environmental variable to be taken into account in fishery management strategies. The activities proposed are based on a suite of simulations with an Earth System Model (ESM). These simulations include reconstructions of the biogeochemical state of the Atlantic ocean for the period 1960 to present and a set of near-term predictions initialized every 3 years for the period 1979 to present.  The simulations are designed to test the ability of two different initialization techniques to provide predictive skill to the NPP prediction. One initialization technique is based on data-assimilation of physical fields only. As an absolute novelty, the second technique proposed is based on the reconstruction of 3D nutrient fields. This combines information from climatological nutrient fields and reconstructed water masses variability. This combination is meant to exploit the ability of Atlantic mode waters to propagate a signal on nutrient distribution on interannual timescales providing a source of predictability for nutrients and thus for NPP. Skill scores will be used to validate the near-term predictions derived from both techniques and the best performing one will be extended to 10-year forecast and initialization every year in order to obtain a complete evaluation of the predictive capability of the modeling system (ESM+initialization technique).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Glyco-Nanoparticles for Applications in Advance Nanomedicine' (NanoCarb), addressing dissemination and exploitation.

assistant: **Impact**

The advance of nanomedicine requires the development of novel materials with tailored properties, controlled circulation, optimal targeting and therapeutic efficacy after administration.  Nanomaterials engineered with glycans offer multiple possibilities for nanomedicine as these biomolecules when arranged on a nanomaterial surface display strong binding to specific receptors while at the same time the glyco coating can restrict unspecific interactions with proteins, helping to avoid the mononuclear phagocyte system and improved biocompatibility in vivo.The NanoCarb Network will develop novel and well-characterised nanomaterials with synthetic and native N-glycans that will be used for therapeutics and guide development of new drug delivery applications. The project will train early stage researchers at the interface of nanotechnology and glycosciences, with the overall goal of achieving a new generation of professionals in nanomedicine for a prospective career in both academia and industry.To achieve this goal a multidisciplinary consortium has been created including universities, research centres and SMEs with broad expertise ranging from nanotechnology, carbohydrate chemistry, glycoprofiling and in vitro – in vivo screening specialists.  An ambitious training plan will be implemented including courses, outreach activities, participation in seminar, and workshops for the development of scientific and transferable skills.


**Keywords:** bionano interactions,  corona,  sugars,  glycans,  carbohydrates
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Cellular and molecular dynamics of ectopic germinal centre formation in rheumatoid arthritis', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

B lymphocytes are key effector cells in adaptive immune responses against foreign antigens, by producing antibodies and processing and presenting the antigen to T lymphocytes. In healthy individuals B lymphocyte differentiation and maturation takes place in the germinal centres of peripheral lymphoid organs.However, in chronic inflammatory autoimmune diseases (e.g. rheumatoid arthritis, Sjogren syndrome) ectopic germinal centres develop at the sites of inflammation, allowing an (auto)antigen dependent immune response, thus perpetuating the inflammation, and eventually breaking the tolerance mechanisms.Therefore, using both mathematical and animal models, the aim of the present proposal is to clarify the genetic, molecular and cellular mechanisms underlying abnormal B lymphocyte development and function and the formation and maintenance of ectopic germinal centres in autoimmune diseases.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'The evolution of beneficial bacterial symbiosis' in the context of a Seventh Framework call.

assistant: **Objectives**

Diverse bacterial lineages form beneficial relationships with hosts. Identifying the conditions under which relationships with symbiotic microbes stabilize or breakdown is key to understanding the major evolutionary transitions that have arisen from two species joining to form a new higher-level organism.Theory predicts that bacterial mutualism is maintained when partners provide reciprocal fitness benefits. The first step in understanding the evolution of bacterial mutualism is to identify the conditions under which symbiotic microbes have gained and lost beneficial functions. I propose to explore the conditions that have lead to the gains and losses of beneficial functions in the aphid symbiont, Regiella insecticola.  Regiella can protect its aphid host from the pathogenic fungus Pandora neoaphidis, however only certain symbiont lineages confer this beneficial function.The goal of this project is to 1) characterize the interactions between Regiella and its aphid host, and then 2) explore the ecological conditions under which the protective function have been gained and lost. My approach uses comparative genomics to identify genes involved in mutualism, and then using phylogenetic reconstructions I will trace the evolutionary gains and losses of the mutualistic phenotype.The project has all the elements to complete my training as an independent researcher and leader in the study of symbiosis. I intend to start my own research groups at the end of this fellowship, and this project is designed to form the basis of my future research programme. I have much of the skills necessary to begin my own research group, however, there are practical skills that I have yet to develop that will increase the overall strength of my research programme. In particular, I wish to expand my
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Off site emergency management and restoration of contaminated environments' (SAMEN).

assistant: **Innovation**

The main purpose of this project is to provide an adequate platform for a timely data and information exchange between a number of projects pertaining to the radiation protection research programme. These projects belong to different but complimentary fields, and include off site emergency management and restoration of contaminated environments.This thematic cluster will serve a number of purposes: keep coherence, exchange of information, co-operation, help maintain the focus of each individual project on practical issues rather than academics, strengthen the link between the user and developer communities, and last but not least, help define new areas where R&D work is needed bearing in mind the general objectives of the research programme.It is expected that most of the objectives will be achieved through active collaboration among the various groups, participation in workshops, data and information dissemination via both synchronous and asynchronous discussion groups and through a dedicated world-wide-web portal.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'DigitAl and physical incrEmental renovation packaGes/systems enhancing envIronmental and energetic behaviour and use of Resources'.

assistant: **Objectives**

AEGIR’s main objective is to demonstrate a scalable, industrialised, smart, non-intrusive, quick, and affordable four-packaged renovation solution to boost the take up of deep retrofitting achieving nearly zerAEGIR main objective is to demonstrate a physical and digital sustainable framework that boosts the take up of deep retrofitting achieving nearly zero energy buildings. This approach is supported by (i) innovative, industrialized, high performance and non-intrusive multifunctional plug-and-play envelope solutions to increase the use of locally deployed renewable technologies. These solutions can also be modulated depending on the requirements of the target buildings. (ii) A digital ecosystem of services to improve the whole construction workflow (from design, manufacturing, construction, and operation) reducing costs with a sustainable approach. And (iii) a socio-economic model providing financial schemes and business models at building scale. To demonstrate these objectives the project will deploy all these solutions in four demos (Spain, France, Denmark, and Romania) mixing the retrofitting actions which will use the solutions in four different climates. The demos combine different building typologies (multi-family buildings, educational buildings, offices, and single-family buildings) to proof the concept in buildings and tenants with different requirements. One of the demos (Denmark) is social housing so the intention of the project is to demonstrate that these solutions are feasible for the more demanding public. A second demo is a public school to demonstrate the improved air quality and comfort provided by the solution to solve many of the air quality/ventilation problems in this type of buildings. The project involves all the actors from the construction an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Monitoring, Investigation and Response to cyber-attacks with an Adaptive digital twiN moDel for Agile services over the computing continuum' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The growing level of interconnectedness of digital services and infrastructures creates tight and recursive security interdependencies between their providers, which are challenging to address due to the fragmentation of cybersecurity operations. This requires each provider to improve the security posture of its suppliers. However, existing practice, largely based on human interaction for disclosing vulnerabilities, reporting alerts, and suggesting remediations, demonstrates to be largely ineffective and risky.The MIRANDA project aims at operationalising awareness and remediation controls for service supply chains, by addressing feasibility, acceptance, and compliance issues. To this purpose, MIRANDA develops a Cybersecurity Digital Twin (CDT) to model and capture the security posture of such interconnected systems, which is used to detect, hunt, and remediate threats and attacks. The CDT will feature: i) functional and topological representation of digital services; ii) bidirectional control/monitoring data flow with real systems; iii) modelling and behavioural prediction of individual components and whole systems; iv) opaque representation of suppliers’ assets based on confidentiality and privacy requirements. The framework also encompasses the necessary security controls to safely exchange data and controls between providers. On top of the CDT abstraction, MIRANDA builds adaptive and automated processes for threat hunting, detection of lateral movements, and eradication of the root causes of attacks.Validation of individual components and the overall MIRANDA platform will be conducted in three relevant Use Cases, covering different platforms for Smart City services. The purpose will be to demonstrate the adaptability to the evolving context and the effectiveness to s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Digital Lemmatized Edition of Prose 2 (Franco-Italian prosification of Benoît de Sainte-Maure's Roman de Troie)' (PRODIGI) targeting Horizon 2020.

assistant: **Abstract**

The project aims to produce a lemmatized diplomatic digital edition of a hitherto unpublished text of the Franco-Italian Middle Ages, the second mise en prose of Benoît de Sainte-Maure’s Roman de Troie or Prose 2 (ante 1289). The interest of Prose 2 lies, among other things, in being an original French text written in Italy (Veneto). It is therefore a particularly significant witness of the Franco-Italian textual and linguistic galaxy, which has seen a renewed interest over the past decade, especially with regard to the contribution made by Italian scribes in the spread of medieval French literature. Finally, from the point of view of cultural history, Prose 2 is a key component of the Italian reception of the Trojan narrative, a complex panorama that is still being defined in detail. From this perspective, the Paduan-Venetian region between the thirteenth and fourteenth centuries shows a singular receptivity: several cities, primarily Venice and Padua, endorse a mythology of origins entirely based on the world of Trojan heroes. As Trojan history becomes integrated into urban historiography, this “familiarity with the ancient” contributes to the later emergence of a cultural attitude known as “Veneto pre-humanism”. The typology of the proposed edition is a digital diplomatic edition allowing the manipulation of the text for the purposes of linguistic analysis, in particular lemmatization, and the creation of a dictionary of Prose 2, to be also included in the DiFrI-Dictionary of the Franco-Italian, a project based at Padua University. With respect to her background as a researcher, this fellowship will have a crucial impact on the career of the applicant, offering concrete possibilities to attain an academic position. The activities planned during this two-year fellowsh
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Human Rights in Conflicts: The Role of Civil Society' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

The European Union has identified peace making, the respect for human rights and the development of civil society as key priorities in its external relations. Non-governmental actors have become key players in ethno-political conflicts, both as violators and as promoters of human rights.This has been facilitated by the transformation of these conflicts, increasingly characterised by high intensity in intra-border ethno-religious tensions and strong international appeal to human rights protection. Yet neither have the precise inter-relationships underpinning the human rights-civil society-conflict nexus been fully understood, nor has the potential complementarity between non-governmental and EU actors been sufficiently explored.Shur's overall objective is thus to analyse the impact of civil society on ethno-political conflicts through human rights, and to identify the means to strengthen the complementary actions of civil society and EU actors. It does so by analysing four case studies in the European neighbourhood: Bosnia-Herzegovina, Cyprus, Turkey-Kurds, and Israel-Palestine. Through the comparative examination of these cases, Shur will draw-up policy guidelines tailored to governmental and non-governmental vil society action.