RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Adriatic Perspectives: Memory and Identity on a Transnational European Periphery' (ADRIA).

assistant: **Concept**

This project analyses the construction of collective identity and territorial belonging by examining selected monuments in the historical region of the northern Adriatic that today is shared by Italy, Slovenia and Croatia. The links between historical memory and modern forms of identification are most complex and unstable in ethnically mixed regions with a long record of political and symbolic border shifts. Building on my previous archival research on the history of the region, I aim to develop a more complex understanding of the links among identification, belonging, nationality and the symbols used to invoke all of them. This project will apply the tools of various disciplines, including history and anthropology in order to understand how cultures of remembrance and politics of memory form, intertwine and overlap in transnational areas. In this new project, I am adopting a genuinely comparative and transnational perspective and I must test new methodological arguments by applying the methods of emerging border studies. The intertwining of these two methodologies is still underdeveloped in historical research. I will analyse the memory landscapes of three port-cities from the beginning of the twentieth century to the present: Trieste/Trst (Italy), Koper/Capodistria (Slovenia), and Rijeka/Fiume (Croatia). The project is divided in five work-packages: Management (WP 1), Dissemination (WP 2), Imperial Sites of Memory (WP 3), World War I Sites of Memory (WP 4) and World War II Sites of Memory (WP 5). With this project I will make an original contribution to the modern cultural and social history of Europe that should be of interest to scholars, decision makers, cultural managers, teachers and to European society in general. My stay at the EUI will not only increase my his
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Transformation of 'analogue' testing procedures into 'digitalized' testing procedures in high-voltage equipment' to be submitted under Fourth Framework.

assistant: **Abstract**

ObjectivesThe aim of this project is to:-define one or more sets of parameters to characterise lightning impulses-write a report in which the relevancy of the proposed parameters are explained-establish unambiguous algorithms to calculate these parameters-write a proposal for the relevant parts of IEC 60060-1 and IEC 61083-2.State of progressIn the first work package of this project the current problems among manufacturers, test laboratories and calibration laboratories were inventorized. It appeared that the problems are even greater than the project team had expected. Also a literature investigation was made, in the literature written in the last 10 years little information could be found about this subject. In the second work package (investigation towards the relevancy of the conventional and new parameters) a software package to evaluate both the conventional parameters as well as some new ones was developed by one of the partners. The software was tested with analytical and actual measuring data and the software showed good results. For the test purposes a special generating circuit was designed. Simulations with this design were performed and they showed good results. The project team decided to use this design and the generating circuits are being built. Also a test procedure for the determination of the influence of overshoot, oscillations and some other parameters was designed. Actual testing on specimens is finished and some ideas for new parameters and their calculation method will be proposed to international bodies to be placed in standards. To inform others about this project several papers have already been published and presented. It is know that in the near future papers will be published.BackgroundExperts in high-voltage and high-power testing have re
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Comparative modelling of organoids in the age of single-cell transcriptomics' (OrganoidAlign) under Horizon 2020.

assistant: **Objectives**

The OrganoidAlign action will develop a solid computational framework for comparative modelling of organoids in the age of single-cell transcriptomics. It will provide direct payoffs to both, tissue engineering and single-cell genomics fields. The overarching goal is to build a set of statistically rigorous and consistent probabilistic models for aligning a single-cell transcriptomic profile of an organoid against its in vivo tissue, for quantitatively evaluating its recapitulatory power. During the course of this action, a meticulous review will be conducted on the state-of-the-art single-cell data modelling and comparative analysis techniques prior to formulating the single-cell transcriptomic profile comparison problem in statistical learning theory. This will specifically focus on both cell clustering and cell trajectory inference methods. A new statistical framework will be implemented to accommodate a comprehensive comparison between a pair of in vitro and in vivo transcriptomic profiles. A rigorous scoring measure will be devised to quantify their alignment. Overall, the inference components under the proposed framework will facilitate the prediction of missing or outlying cellular attributes, transcriptional factors and signaling pathways in organoids compared to their in vivo tissues, informing directions of organoid protocol improvement. Overall, its outcomes will have potential contributions towards engineering more reliable in vitro tissue models, as well as reference profiling of organoids under the Human Cell Atlas project.


**Keywords:** Single-cell Genomics ,  Organoids ,  Machine Learning ,  Missing Factor Prediction
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Topological dynamics and chaos on compact metric spaces' (TOPDS) targeting Seventh Framework.

assistant: **Abstract**

In the paper ""Measure of chaos and a spectral decomposition of dynamical systems of interval"" (which extends Li and Yorke approach stated in their famous paper ""Period three implies chaos"") Schweizer and Smital introduced the definition of distributional chaos. Scientific aim of this project is to study distributional chaos and its relations to other notions known from Topological Dynamics. Main problems we will cosider are the following: - how ''large'' distributionally scrambled sets can be form topological, measure theoretic or dimension theory point of view? - what are sufficient conditions (topological mixing, specification property, topological exactness, shadowing) to ensure distributional scrambled  sets being uncountable, perfect, invariant, etc. ? - what are condition not strong enough to imply distributional chaos in general case (e.g. it is known that positive topological entropy or weak mixing belongs to this class)? - are there any other spaces (graphs, dendrites, low-dimensional continua) which guarantee equivalent conditions from Schwaizer and Smital paper to hold (it is known that there is no equivalence in general, in particular in dimension two or zero)? Additionally, we will study shift spaces and their generalizations for a better understanding of the notion of ''complexity'' in the theory of dynamical systems. The research undertaken in this project aims to extend knowledge about chaotic phenomena in dynamical systems.  The main aim of the project is to extend knowledge and research experience of the researcher to the level that he is able to prepare his habilitation thesis. The researcher will present obtained results at international meetings. He will extend his scientific collaborations and start new independent lines of research in his care
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Episomal vectors as gene delivery systems for therapeutic application' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Many chronic human diseases cause great suffering as a result of inherited and sporadic genetic mutations. Gene therapy provides therapeutic benefit if a normal copy of the affected gene can be expressed in appropriate target cells. Retroviruses are often used for gene delivery, as the therapeutic gene integrates into a host cell chromosome. As integration is targeted to active chromatin this ensures long-term expression. However, this can disrupt gene expression at the integration site and lead to cancer. We propose that safe DNA vectors for human gene therapy must deliver therapeutic levels of gene expression without altering patterns of expression in the host cells. Extra-chromosomal gene expression vectors provide the best way of achieving this. Results will provide novel DNA vectors and protocols that will be used as gene delivery systems for therapeutic application. Expression vectors will be developed using rational design parameters that incorporate existing knowledge of genetic and epigenetic factors that regulate chromatin function in mammalian cells. DNA vectors will be designed specifically for ectopie gene expression from extra-chromosomal loci in the host cells, to provide regulated gene expression for safe, efficient and sustained gene therapy. Extra-chromosomal gene expression vectors will be validated for human gene therapy in a pre-clinical setting and protocols for clinical application established. Prototype extra-chromosomal gene expression systems that provide efficient and sustained gene expression will be refined to develop second-generation gene therapy vectors. We will use a systematic analysis of genetic elements to define design parameters for rational vector construction. The performance of second-generation gene expression vectors will be va
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Construction and characterisation of hybrid si/high temperature superconductor field effect transistors' to be submitted under Fourth Framework.

assistant: **Abstract**

Research objectives and content We propose to develop a p-channel Insulator Superconducting-Gate Silicon Field-Effect Transistor (ISGSFET) which will used for creating a prototype of a lT/lC memory cell. Such a cell is a building block for a Ferroelectric Random Access Memory (FERAM) based on a silicon/high temperature superconductor (HTS)/ferroelectric heterostructure. This is a first attempt in making a complete hybrid Si/HTS memory device optimised for operation at low temperatures. The project is divided in two parts. The first part consists of the construction and characterization of the ISGSFETs. The second is the building of a prototype of a Si/YBa2Cu307-x/(SrxBal-x)TiO, memory cell. The ion implantation and the project the transistor structures will be done in close collaboration with the Institut Eur Mikrotechnik Mainz (IMM). All the steps related to the deposition and patterning of the superconducting and ferroelectric oxides will be done at the Institut fur Phy of the U. Mainz. Training content (objective, benefit and expected impact) The candidate will learn about the epitaxial growth of HTS and other oxides like YSZ and CeO2on silicon. He will be abl interact with experienced professionals in the field of design and fabrication of Integrated Circuits. At the end of the proje the strong background in superconductivity and cryogenics will be fundamental for the investigation of the properties of t devices. Links with industry / industrial relevance (22) The group has long term collaborations with the Research Laboratories of the Daimler Benz AG and the Hoechst AG in Frankfurt (Germany). New research projects in collaboration with the Institute for Micro-mechanics Mainz (IMM) are in preparation. This is a profit oriented state owned enterprise which is operate
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Quantum Repeater Architectures Based on Quantum Memories and Photonic Encoding' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

At the heart of all anticipated network-based quantum applications lies the requirement to establish quantum communication between individual network nodes over long distances. Quantum communication exceeding 100 km requires so-called quantum repeaters to extend communication beyond this limit. Mainly two types of quantum repeater schemes are being investigated: Quantum-memory-based schemes for long-distant entanglement generation and photonic encoding-based schemes for fast secure quantum communication. To date, both schemes have only been considered individually, however, a hybrid approach could overcome their distinct limitations and benefit from individual advantages. How such a system could be realized remains an open question.This project addresses the challenges, benefits, and resource requirements for a hybrid architecture of interconnected photonic-cluster-state-based and quantum-memory-based quantum repeaters. In a theoretical study, cost parameters of such a hybrid quantum repeater for realistic system properties will be determined for the first time. Experimentally, electron spin coupled quantum dot single photon sources will be employed as resource for multi-photon cluster state generation. In parallel, a new type of quantum memory—the SnV defect in diamond, will serve to demonstrate remote entanglement. Finally, these two disparate systems will be interconnected via frequency conversion and Bell-measurements—to demonstrate cross-platform entanglement. Investigating for the first time an interconnected system of two disparate solid-state resources for quantum communication will stimulate ground-breaking research towards hybrid quantum repeater architectures.All three objectives will benefit from the PI’s recent expertise in spectroscopy, spin control, and n
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Hybrid cooling system for semiconductor detectors of X- and Gamma- Rays' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Semiconductor detectors  for x- and gamma-rays registration are widely used in nuclear energetic and ecology, geology and mineral resource industry, medicine and scientific research activities,  other spheres. To provide the best performance in all applications, HPGe and SiLi detectors require a cooling till liquid nitrogen (LN2) temperatures. In general cooling system semiconductor detectors are installed in vacuum cryostat which is submerced to Dewar vessel with LN2.  In the process of using LN2 there is constant boiling and evaporating of LN2 and therefore there is a permanent necessity to control a LN2 level in Dewar vessel and to fill it with the certain periodicity. Typical periodicity for 20-30 l volume change is once per week. Refilling these volumes is problematic due to its need for permanent attention and that automatic filling requires special expensive equipment. This proposal declares a technology where refilling of LN2 is needed with much lower periodicity (about once in a year). This hybrid cooling system includes cryostat with semiconductor detector, Dewar vessel with LN2 for detector cooling and electrical cooler for condensation of evaporated LN2. Such system should be hermetically closed. The current system provides the re-use of resources (LN2) so giving the contribution in the sustainability of resources and energy efficiency. The following project realizes the feasibility study for the development of advanced hybrid cooling system for semiconductor detectors.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Research with and for society in EUNICE' under Horizon 2020.

assistant: **Concept**

REUNICE is a strategic project for the European Universities Alliance EUNICE which aims to align its education, research and innovation strategies through an ambitious and transformative agenda. This agenda is trans-disciplinary, intercultural, shared, and provides a long-term joint strategy for a ‘customized’ university. Becoming a true European university through REUNICE will support the efforts of the Alliance to contribute to the development of a society based on knowledge and innovation, also considering smart, sustainable and inclusive growth.The implementation measures proposed aim to provide concrete life experiences for the university community as a whole. Individual experiences are focused on the development of personal attitudes such as openness and sensitivity to individual and community particularities. Institutional experiences contribute to institutional change that guarantees inclusiveness and forward-facing principles for the Alliance members.To achieve this ambitious goal, REUNICE is building cooperation between Science and Society, recruiting new talents for science and pairing scientific excellence with social responsibility. Cooperation with non-academic actors, mainly academia-business cooperation, will be reinforced. The scientific community, industry, professional organizations, policy makers, civil society and public authorities will be involved in exploring and supporting citizen science through the Alliance Competence Center, a pilot initiative clustering activity to share best practices, research infrastructures and innovation resources.REUNICE will allow the alliance to develop an ambitious common research and innovation agenda and action plan that, in turn, will address the societal challenges identified by the H2020 programme. It will cont
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Multiphosphorescent emitters based on Tris-Heteroleptic Iridium Complexes'.

assistant: **Concept**

The aim of the proposal is to develop a new family of phosphorescent iridium(III) complexes as dual phosphorescent emitters. The goal is to obtain a complex with a first phosphorescent band below 500 nm and a second around 600 nm in order to have white emission.The strategy revolves around a tris-heteroleptic cyclometalated iridium complex with two different main C^N ligands and one ancillary ligand. The tris-heteroleptic nature of the complex leads to two possible triplet emitting states, T1a and T1b, due to the excited state possibly localized on one or the other C^N ligand.In addition of providing novel insights and tools for understanding and controlling the properties of phosphorescent organometallic materials, the long term goal is to achieve white emission from a single emitting center for electroluminescence applications.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Deconstructing the role of SUMO on chromatin in cell identity and tissue repair' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The maintenance of cell identity and how it is subverted in disease are central questions in biology and medicine. The interplay between transcription factor and chromatin configurations plays a key role in maintaining cellular identity, yet how this interplay is regulated is poorly understood. Notably, the existence of possible general mechanisms underlying different cell-state specifications remains to be determined. We have recently uncovered evidence that sumoylation, which deposits a chromatin-associated mark (SUMO) that principally targets transcriptional regulators, acts as a general barrier to cell-fate transitions and enforces two distinctive chromatin types to safeguard somatic and pluripotent cell identities.  The central paradigm for the proposed work is that SUMO functions as a general stabilizer of critical chromatin-bound determinants of cell identity and that the equilibrium between conjugating/deconjugating activities provides a general regulatory mechanism for their dynamic targeting to key chromosomal loci, thus actively contributing to cell-fate change. Focusing on reprogramming to pluripotency and transition to totipotent-like states, we propose to: 1) identify relevant locus-specific SUMO substrates/complexes in fibroblasts and ESCs, 2) define the role of SUMO in regulating their function and dynamics and, reciprocally, 3) explore the sumoylation/desumoylation balance that accompanies cell-fate change. A complementary effort seeks 4) to exploit these experimental approaches to study a paradigmatic pathophysiological process involving rapid cell-fate transitions: tissue repair following muscle injury.   With a vision toward targeting this druggable pathway for regenerative medicine and cancer treatment, we expect these studies to integrate the gene