RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Exploring Eco-efficient blended cements: Innovations in performance and sustainability' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Europe is committed to achieve the ambitious goal of reducing greenhouse emissions and to transition towards an energy-neutral built environment by 2050. The construction sector, which contributes >70% of CO2 emissions in many countries, urgently needs to adopt greener practices. In response to this challenge, this research combines materials science, environmental science and civil engineering to develop new novel cements with the potential to reduce CO2 emissions from Portland cement by up to 40%. The main aim of this project is to develop an innovative and comprehensive approach to optimizing the design of new ultra-low clinker hybrid alkaline cements (HAC), using treated low-purity clays as cement replacements, in combination with sodium sulfate. This will be achieved by:- Determining the effectiveness of calcination or mechano-chemical (MCA) activation in enhancing the pozzolanicity of low-purity clays, focusing on revealing nano-structural alterations induced by such treatments in the clay structure/ mineralogy.- Elucidating the factors controlling the fresh state properties of HAC produced from calcined or MCA clays, focusing on rheology, reaction kinetics and in-situ characterisation of the reaction products forming <48h of reaction.- Revealining how mix design formulations of HAC control their phase assemblages evolution, this is interrogated by using conventional characterization techniques, along with advanced synchrotron techniques including advanced computerised X-ray tomography techniques.- Creating an experimentally validated thermodynamic modelling to predict of the phase evolution of HAC, as a function low-purity clays chemistry and mix design parameters.This project will allow the identification of key strategies that will help transform the use of low
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Towards the dialogue on integrative transition policies - a European conference on education, training, welfare and labour market policies for young people' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

This proposal aims at promoting a cross-sectoral approach in policies addressing youth transitions. For this purpose the project will organize a European conference. In this conference, results of different European research projects and thematic networks in the areas of training, labor market and youth policies for young people will be exchanged and discussed. The objective of the conference is to outline an approach of integrated transition policies. This interdisciplinary and integrated approach presented to and discussed with policy-makers, NGO and administration responsibles from national and European levels may lead to a diversification of opportunities for young people.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Mathematics of Scattering Amplitudes' (MaScAmp) under Horizon Europe.

assistant: **Objectives**

MaScAmp proposes a new paradigm for fundamental interactions in physics in the form of a unified mathematical approach to scattering amplitudes. The project brings together a multidisciplinary team with expertise in pure mathematics and theoretical physics who will develop a set of novel and efficient algorithmic methods with applications in mathematics, particle physics and gravity.Discoveries in many areas of fundamental physics depend upon a detailed understanding of the scattering of particles. Modern experiments, such as particle colliders and gravitational-wave detectors, demand high-precision theoretical computations to make new discoveries. These are deduced from physical models by a highly labour-intensive process relying on the calculation of scattering amplitudes, which assign probabilities to particle interactions. Despite a tremendous worldwide effort over many decades, the methods used to compute increasingly complex scattering amplitudes remain disparate and fragmented. The work of the PIs in distinct domains suggests unexpected symmetries and universal rules obeyed by scattering amplitudes in different-looking areas of physics. This calls for a radically new way of studying scattering amplitudes.MaScAmp will create a unified framework for the calculation of general scattering amplitudes by building upon the latest research in mathematics, notably in algebraic geometry and number theory. As a result, MaScAmp will overcome longstanding computational bottlenecks, push the boundaries of numerous areas of theoretical physics, such as quantum field theory, gravity and string theory, and inspire new mathematical research. A widely applicable computer software implementation will enable physicists to make previously inaccessible predictions for present and futur
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Validation of blood-brain-barrier permeability as a glioma biomarker by means of the radiotracer 99mTc-tetrofosmin and single-photon emission computer tomography', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Objective of GLIOMARK is to clinically validate the permeability of the blood brain barrier (BBB) as an in vivo biomarker for the diagnosis and grading of gliomas. This will be accomplished by means of the radiotracer 99mTc-tetrofosmin (TTF) and the imaging technique Single-Photon Emission Computer To-mography (SPECT). The outcome of GLIOMARK is GlioTect, a diagnostic kit containing handling/diagnostic instructions and tetrofosmin. The latter has to be reconstituted with 99mTc pertechnetate to yield TTF, which will be used in combination with SPECT. Often computer tomography or magnetic resonance imaging are unable to detect low-grade gliomas or distinguish glioma from other diseases. Hence, brain biopsies are necessary for confirmation of diagnosis and grading of gliomas. GlioTect with TTF/SPECT enables reliable, fast differential diagnosis and grading of gliomas as non-invasive method. This has an immediate impact on the type and aggressiveness of subsequent therapies.Gliomas are recognized as a rare tumor disease with poor prognosis and orphan diagnostic designation for GlioTect will guarantee 10 years of market exclusivity upon approval. ProActina, a Greek chemical-speciality SME having identified this innovative niche market opportunity could become global market leader in glioma diagnostics. Development is at TLR level 6-7 and will be lifted to 9. Expected market application is the sale of GlioTect for preparation of TTF for use with SPECT. End users are hospitals that use the kit to reliably diagnose or exclude gliomas without the need for expensive equipment.Taken together, the aggregated unique selling point of SPECT in combination with TTF (generated by means of GlioTect) is the first ever and only glioma diagnostic, which assesses a clinically validated gliom
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Silicon integrated lasers and optical amplifiers' (SILAMPS) targeting Seventh Framework.

assistant: **Abstract**

This project is a six year programme of work to develop fully integrated optical emitters, lasers and optical amplifiers in silicon.  Recent years have seen tremendous advances in the development of silicon photonic devices.  However, the last hurdle to full silicon photonic systems and optical data transfer on and between integrated circuits are electrically pumped optical amplifiers and lasers in silicon using a CMOS compatible technology.  Consequently, there have been massive efforts worldwide to search for efficient light emission from silicon.  Our team made a major initial breakthrough producing the first LED in bulk silicon - published in NATURE (1997).  Although a world first, this device only operated efficiently at low temperatures.  This problem was solved using a new nanotechnology - dislocation engineering - reported in NATURE (2001) - and crucially uses only conventional CMOS technology.  The development of this into a silicon injection laser and optical amplifiers is the essential next step for high technology high value applications. We have recently made a further breakthrough by obtaining extraordinary optical gain in erbium doped silicon that now offers a realistic route to this goal. Currently the incorporation of lasers and amplifiers on silicon platforms can only be achieved hybridizations of active devices based on III-V materials ""pasted"" on to silicon waveguides and cavities.  Gain has been reported using four-wave-mixing and Intel has recently demonstrated a Raman laser in silicon but both rely on purely optical-to-optical transitions and are fundamentally unable to be electrically pumped.  We believe we have the only route that has the potential to produce electrically pumped amplifiers and lasers with room and higher temperature operation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Exploiting the power of human induced pluripotent stem cells to generate synthetic retinae in vitro for cell based therapies, drug discovery and disease modelling' (RET-iPSC) targeting Seventh Framework.

assistant: **Abstract**

Blindness represents an increasing global problem with social and economic impacts both for the patients and society in general.  Recent estimates indicate that the overall number of people with visual loss is 285 million globally, of whom 39 million are blind. In Europe, approximately 1 in 30 individuals experience sight loss and 75% of those are unemployed, a social burden which is anticipated to double by 2020 as the population of Europe ages. Diseases affecting the retina, the light sensitive extension of the central nervous system lining the back of the eye, account for approximately 26% of blindness. To date, there are no treatments to restore lost retinal cells and visual function and there is an urgent need for new therapeutic approaches. A pioneering breakthrough has highlighted the possibility of generating synthetic retinae from stem cells under laboratory conditions. This research is in its infancy and needs to be developed so human synthetic retinae can be produced efficiently and reproducibly from patient-specific stem cells. Very recently, my group has developed a unique method that results in conversion of human embryonic stem cells to fully laminated retinae containing all retinal cell types under laboratory conditions. In this project we aim: (1) to develop a robust differentiation method for generation of synthetic retinae that can be applied efficiently to a large number of patient-specific induced pluripotent stem cells; (2) to  investigate that laboratory derived synthetic retinae contain functional retinal cells which are equivalent to native cells arising during human development and can contribute to restoration of vision upon transplantation into degenerate retinae and (3) to develop preclinical tools that will enable us to select functional re
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Abundance of rational points on low-degree del Pezzo surfaces' (AbundantPtsDelPezzo) targeting Horizon Europe.

assistant: **Abstract**

Describing the set of rational solutions to polynomial equations is the oldest field in mathematics and one of the fundamental goals in number theory. In arithmetic geometry such solutions are studied using geometric tools: rational solutions to equations correspond to rational points on the corresponding geometric object.Fano varieties are among the simplest geometric objects, but still far from fully understood. This makes them a great class to test conjectures and develop new techniques. It is generally believed that Fano varieties, if they have a rational point, should have many, and they should be well-distributed. For curves (dimension 1), this is the case. Fano varieties in dimension 2 are del Pezzo surfaces, and already here there are many open questions. These surfaces have been a very active area of research in the last 50 years.Del Pezzo surfaces are classified by their degree, an integer between 1 and 9. The lower the degree, the more complex these surfaces become, and especially del Pezzo surfaces of degree 1 are notoriously difficult. Current results on the rational points on these surfaces make use of ad-hoc constructions, and a general geometric approach is missing. This forms a sharp contrast with del Pezzo surfaces of higher degree, and leaves a big gap in the understanding of rational points on Fano varieties.This project proposes to create a systematic approach to construct rational points on del Pezzo surfaces of degree 1, and use this to prove several different results on abundant rational points for new families of surfaces. This will lead to answering big open questions (unirationality, Hilbert property and weak weak approximation for del Pezzo surfaces of degree 1), and providing evidence towards a long-standing conjecture on rational points on
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'ENVIRONMENTALLY COMPATIBLE OPTIMIZATION OF EAF SLAG FOR LOW-CARBON ADVANCED GREEN CEMENT' (ECO-SLAG-CEM).

assistant: **Innovation**

The ECO-SLAG-CEM project aims to develop high-performance, low-carbon cements using modified Electric Arc Furnace (EAF) slag. The project addresses the significant CO2 emissions from the cement and steel industries, which together account for approximately 14% of global CO2 emissions. The primary objective is to enhance the reactivity of EAF slag through high-temperature treatments and bio-based activation systems, enabling the formulation of high-performance, low-carbon binders to replace the declining availability of granulated blast furnace slag (GBS).To achieve this, the project follows a twofold approach: high-temperature treatments to increase the intrinsic reactivity of EAF slags and the development of tailor-made activation systems, including the use of bio-based chelatants to pre-treat slags and accelerate hydration. A further focus of the project is the presence and mobility of Fe and heavy metals to ensure durability and compliance with environmental standards. The relevance to the work program lies in its alignment with the Horizon Europe Pathfinder Challenge ""Towards cement and concrete as a carbon sink."" The project aims to develop low-carbon binder technologies, optimize clinker reduction, and provide valuable data on the structure and behavior of Fe-bearing slags. By valorizing EAF slag, the project supports the decarbonization of the cement industry and adds value to the steel production process, making it easier to adopt globally and boosting the competitiveness of European steel production. The project involves collaboration between various partners, including universities, research institutes, and industry players, ensuring a comprehensive and interdisciplinary approach. The expected outcomes include the development of treatment strategies for EAF
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Mechano-activated Extracellular Vesicle Based Repair of Bone'.

assistant: **Concept**

Every 30 seconds a person suffers an osteoporosis-related bone fracture in Europe, resulting in significant morbidity, mortality and healthcare costs estimated at €36billion annually. Current anti-catabolic therapeutics are associated with severe side effects and are purely preventative, while the only anabolic treatment plateaus at 6 months. This has resulted in a crisis in osteoporosis treatment. Therefore, the aim of EVERBONE is to develop and commercialise a new anabolic multitargeted medicinal product for bone regeneration that mimics the beneficial effects of physical exercise, by recruiting endogenous cells to promote angiogenesis, osteogenesis and bone formation. Building on the discovery that osteocyte-derived mechanically activated extracellular vesicles (MAEVs) mediate the anabolic bone forming response to physical exercise, this project will develop novel bioreactor systems to increase MAEV yield in vitro and scale up for clinical use. Secondly, it will identify a standard mechanical conditioning procedure to generate optimised angiogenically and osteogenically primed MAEVs. Finally, preclinical evaluation of MAEV treatment will be performed in a model of osteoporosis and bone healing, whereby it is expected that MAEVs will localize to bone and mobilise endogenous endothelial and stem cell populations to enhance bone regeneration in osteoporosis and improved healing rates in bone defects. This regrowth of bone will overcome current limitations of anti-resorptive treatments, reducing the risk of fracture and thus the financial burden of treatment. The project will leverage the applicants experience in bone mechanobiology to develop a new product with significant commercial potential. Therefore, the impact of EVERBONE will be multifaceted: it will transform ho
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'An ultrasonic level detector for use on canning lines' (1994-1998).

assistant: **Innovation**

The food packaging industry has for some time now made use of an on-line sensor to monitor the level of liquid in cans or bottles after they have been filled on the production line. Such devices generally employ a source of gamma radiation which propagates through the side of each can as it passes. The attenuation of the radiation is measured by a detector on the other side, thus indicating if the can is full at the level of the detector. This system presents two problems; -- The system only detects the presence of liquid at the level of the sensor. A can filled too low will be detected, but a can filled too high will register as being correctly filled. There is no quantitative measurement of the height of the liquid. The utilisation of a gamma emitting isotope presents health and safety problems in the use of the sensor, as well as in disposal of the unit at the end of its working life. There is a need for an alternative detection system which measures the exact height of liquid in each can as it passes on the production line. The possibility of weighing each can is inappropriate for the speed of production lines, and so novel methods should be developed. The proposed system to be developed within this project will incorporate a small waterjet (a few mm high) which will strike the bottom of each can as it passes. This contact will mediate an ultrasonic pulse, which will travel through the bottom of the can, and through the liquid inside. Air is an effective barrier for ultrasound, and the pulse will reflect off the liquid/air boundary. By measuring the time of flight" up and down the can, it is possible to calculate the level of liquid inside. Such a system will be considerably safer, more accurate, and much more versatile than the present level detectors. "