RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Tackling the global plastic waste issue, by upcycling no value streams into 100% virgin material and enabling new plastic circular economy' (2014-2020) under Horizon 2020.

assistant: **Objectives**

72 million tons of PET (the second most used plastic polymer) are produced each year from petroleum refining. The same year, 53 million tons of waste PET is landfilled, incinerated or floats into seas and oceans. Gr3n proposes a completely new way to break this vicious circle and create plastic from waste.The problem with PET is that it is currently “reused” and not “recycled”, as only transparent and pale bottles are mechanically treated to be partly added to virgin PET in the production of plastic bottles and trays. All other PET derived products, as waste polyester textiles and coloured plastics are almost worthless to the market and end up polluting the environment.Our vision is to enable the first truly circular approach to PET recycling, empowered by our patented technology able to break any kind of PET into its two main building blocks, for creating new PET plastics infinitely and cost-effectively.Through a 15,000 tons/year gr3n plant we do expect to collect, process and address the need of virgin plastics and polyester of a metropolitan area, thus triggering a true circular approach to plastic recycling. The cPET project is focused on validating the sustainability of creating a European distributed network of gr3n plants localized in each urban area, able to treat any PET-derived waste and produce new plastic for local consumption. This SME Instrument innovation project aims to tear down all the technical, economic, regulatory and logistics/organizational risks to scale up the initial 1,000 tons/year demonstrator to a full-fledged industrial plant.This will be achieved through a real demonstration is a small urban area, where a circular approach to PET recycling will be really tested, streamlining the logistics and measuring the economic, environmental and socie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'High performance scratch-resistant coatings applied to thermoplastic articles by in-mould coating processes' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

One of the major drawbacks of thermoplastic materials (widely used to produce shaped articles) is the unsatisfactory scratch and wear resistance, leading to reduced lifetimes of the shaped articles due to functional and/or aesthetical reasons. The strategic objective to the proposed research is to develop and evaluate a new flexible high performance scratch resistant coating material in combination with an in-mould coating technology usable in the injection molding process to provide a coating technology for the protection of a large variety of commodity thermoplastics, providing good adhesion to the sub- strate material without the need of additional pre-treatment and, if necessary, high transparency. It is intended to show that it is possible to match specific and highly sophisticated technical requirements with respect to both the material and the process. Specific objectives are the development of a new composite coating material, which meets the special requirements of the molding processes, leading to new products with exceptional economical and ecological selling arguments and the development of an in-mould coating process to apply and cure these coatings.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Building Innovative Knowledge Management Infrastructures Within European Public Administrations' in the context of a Fifth Framework call.

assistant: **Objectives**

The KIWI project is aimed at developing innovative knowledge management (KM) infrastructures able to transform public administrations at any level inside Europe into knowledge driven and dynamically adaptive learning organisations and empower public employees to be fully knowledge workers.KIWI will result into the implementation of intelligent environments enabling public employees to access, across departments, levels and public administration layers, one stop shop KM services through fixed and mobile terminals (thus supporting anytime and anyplace government). The project will especially have a focus on the engineering of the knowledge management process and the management of human resources, by supporting specific processes such as public employee development and team building in large, multi-site national and regional administrations.OBJECTIVESThe KIWI project is aimed at developing innovative knowledge management (KM) infrastructures able to transform public administrations at any level inside Europe into knowledge driven and dynamically adaptive learning organisations and empower public employees to be fully knowledge workers. KIWI will result into the implementation of intelligent environments enabling public employees to access, across departments, levels and public administration layers, one stop shop KM services through fixed and mobile terminals (thus supporting anytime and anyplace government). The project will especially have a focus on the engineering of the knowledge management process and the management of human resources, by supporting specific processes such as public employee development and team building in large, multi-site national and regional administrations. Within KIWI, the knowledge management process will be deeply analysed and redesigned acc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Analysis of evolutionary conserved signalling pathways mediating polar leaf development in dicotyledonous plants' (EVOSIGNAL) under Seventh Framework.

assistant: **Objectives**

Like all seed plants, the body of the model plant Arabidopsis thaliana consists of two distinct systems, the root and the shoot. The shoot system contains the shoot apical meristem (SAM) harboring a population of plant stem cells. During the vegetative growth phase the population of stem cells in the SAM divides asymmetrically and produces the cells that will eventually form new organs. Leaves are initiated at the periphery of the SAM in a circular fashion. Proper establishment of the ad/abaxial (top/bottom) axis is of great importance because shape and size of the outgrowing leaf blade highly depends on the juxtaposition of ad/abaxial tissue. Several genes have been isolated that are involved in specifying either adaxial or abaxial cell fate. These genes often act as master regulators. As a postdoctoral fellow I have generated transgenic Arabidopsis plants expressing inducible versions of some of these master regulators. Using microarrays, we have identified target genes of these master regulators in Arabidopsis. In order to validate unknown or hypothetical proteins which are targets of these master regulators I am proposing experiments directed to identify evolutionary conserved signaling pathways. Therefore I have established transgenic Cardamine plants, which are closely related to Arabidopsis, expressing these inducible master regulators. Transformation of a more distant plant species, Aquilegia, is currently in progress. Using a combination of microarray and next generation sequencing approaches we aim to identify target genes of these master regulators in Cardamine and Aquilegia plants. The identification of these target genes will allow us to study evolutionary conserved signaling modules as well as to define unique signaling pathways. These investigations will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Massively scaling-up protein-protein interaction mutagenesis.' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Understanding, predicting and engineering protein-protein interaction (PPI) affinity and specificity is a key problem in molecular biology. In particular, we do not know how sequence-to-affinity encoding works at a quantitative and mechanistic level and we cannot predict and engineer the effects of mutations on PPIs. To tackle this problem, we need to generate large amounts of quantitative biophysical measurements. Until now this was not possible due to the low throughput of classic biophysics techniques. Here we propose to expand high-throughput deep mutational scanning (DMS) methodology to quantify the effects of tens of millions of mutations on hundreds of PPIs. To generate a dataset of sufficient size and diversity to train models to predict changes in binding affinity from sequence, we will perform combinatorial trans mutagenesis by combining single mutants in the interaction interface of each partner of a given PPI and quantify the change in binding using a highly-validated protein complementation assay (PCA). To establish the platform, we will first focus on mutating PPIs of the KRAS oncoprotein. We will then scale up this approach to mutate at least one hundred structurally diverse PPIs. The resulting dataset will be of unprecedented size and standardisation, serving as a landmark reference dataset for us and others to train and evaluate models to predict the effects of mutations on interaction affinity. These data and models should transform our ability to understand clinical variants affecting PPIs and allow us to better understand, drug and engineer PPIs critical for medicine and biotechnology.“DeepScalePPIs” will be supervised by Prof. Ben Lehner (CRG, Barcelona), whose group has pioneered the use of deep mutagenesis to understand protein structures, dynamic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Behavioural Application Program Interfaces' (BEHAPI), addressing dissemination and exploitation.

assistant: **Impact**

APIs are typically flat structures, i.e. sets of service/method signatures specifying the expected service parameters and the kind of results one should expect in return. However, correct API usage also requires the individual services to be invoked in a specific order.  Despite its importance, the latter information is either often omitted, or stated informally via textual descriptions.  Behavioural Types are a suite of technologies that formalise of this information, elevating flat API descriptions to a graph structure of services.  This permits automated analyses for correct API compositions so as to provide guarantees such as service compliance, deadlock freedom, dynamic adaptation in the presence of failure, load balancing etc.  The proposed project aims to bring the existing prototype tools based on these technologies to mainstream programming languages and development frameworks used in industry.


**Keywords:** Component-Based Software, Static Analysis, Dynamic Analysis, Type Systems
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Crest level assessment of coastal structures by full scale monitoring, neural network prediction and hazard analysis on permissible wave overtopping' (CLASH).

assistant: **Concept**

It has been proven that wave run-up is underestimated by small-scale model tests due to scale effects. Therefore, there is a strong suspicion that wave overtopping will be under predicted too. Full-scale measurements on wave overtopping will be carried out at four sites. One site will concentrate on the effect of long waveson shallow water. Full-scale measurement results are simulated by small scale and numerical modelling to quantify and to explain suspected scale effects. As no generic prediction method for crest level assessment exists, this project will create one. All existing data on wave overtopping will be collected and supplemented with the full-scale data and the 'white spot' data gathered in this project. Information on permissible levels of wave overtopping is poor and vague. A hazard analysis (including socio-economic effects) will give a sound answer tithe question of safety of pedestrians, vehicles, buildings, . . .
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Endogenous business cycles and market imperfections' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

Research objectives and content During the training at the CORE, I will be concerned with the issue of endogenous equilibrium fluctuations. In particular, my investigation will deal will the role of financial intermediation in a capitalist economy in causing and sustaining the instability of market processes. Training content (objective, benefit and expected impact) Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Analysis on fractal-like spaces' (2002-2006) under Sixth Framework.

assistant: **Objectives**

Since the early 1980's physicists have started to investigate analytical and probabilistic problems on fractals, for instance questions about heat diffusion, Brownian motion and vibration. Fractal structures are convenient models for porous materials and hence are of high interest for natural scientists. These structures appear naturally in medicine, biology, economy, physics and chemistry, but also in pure mathematics.The subject of this research project lies on the borderline edge between stochastic processes and analysis on fractal-like spaces. There are four main topics of the project: Analysis of oscillatory phenoma on fractal-like graphs, spectral properties of the Laplacian on fractal-like graphs, heat kernels and function spaces on metric measure spaces, jump processes on fractal-like spaces.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'AcceLerate Innovation in urban wastewater management for Climate changE' (ALICE) targeting Horizon 2020.

assistant: **Abstract**

The challenges facing society in urban wastewater management cannot be solved by any one sector alone. ALICE (AcceLerate Innovation in urban wastewater management for Climate changE) will accelerate innovation by bringing together and exchanging knowledge between the key players who can, together, address the future techno-economic, governance and societal challenges arising from climate change. It will boost international and interdisciplinary skills, as well as careers perspective of Experienced Researchers, Early Stage Researchers, and the workforce of industry, water utilities and public organizations. The results will 1) benefit water utilities, 2) support political and managerial decisions in wastewater, 3) benefit wastewater equipment manufacturers, identifying new market opportunities in the EU, 4) benefit EU citizens from the improved wastewater infrastructure, the environment and job creations.Higher precipitation and more frequent storms will require change in sewer water management. Moreover, higher risks of water scarcity and droughts require increased wastewater reuse, currently at 20% of its potential in the EU. These changes will lead to increased energy demand in a sector that is already a major contributor of carbon emissions. ALICE will promote effective solutions based on innovative technologies, green infrastructures, climate vulnerability assessments, governance and economic models, embracing stakeholders’ and citizens’ views to overcome barriers to the acceptance and uptake of new technologies. The excellence of the project lies in the joined-up thinking of different perspectives and disciplines. Academic and non-academic partners along the wastewater value-chain will exchange knowledge, develop training, research and innovation activities. ALICE
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'An Embolic Protection Device for stroke prevention during heart valve replacement.' (CAPTIS), addressing dissemination and exploitation.

assistant: **Impact**

Aortic stenosis (AS) is the most common and most severe heart valve disease, affecting 20 million people worldwide. Forpatients with severe AS, the most common treatment is valve replacement through Transcatheter Aortic Valve Implantation(TAVI). The procedure is very risky, since embolic debris are released to the blood stream and may reach the brain andother organs, reducing or blocking the blood flow. Strikingly, embolic debris cause new ischemic brain lesions in 70% ofpatients post TAVI, major disabling strokes in 9%, and kidney dysfunction 12.3% of cases. Embolic Protection Devices(EPDs) are being developed to reduce the risk posed by embolic debris during TAVI. To date, only one EPD has beencommercialised for use in TAVI procedure. Unfortunately, the device is poorly effective since it can only provide partialcerebral protection, interferes with the TAVI delivery system, and requires secondary artery access to the TAVI system, thusincreasing procedure time and posing the patient at a higher risk of post-operative side effects.Filterlex developed the CAPTIS® system, an innovative intra-aortic Embolic Protection Device (EPD) for deflecting,capturing and removing embolic particles during TAVI procedure. Easily positioned, deployed and retrieved through thesame TAVI artery access, this revolutionary EPD provides full-body protection by ensuring the best performance in capturingand safely removing the embolic debris released during TAVI. In this way, CAPTIS strongly reduces the risk of stroke andischemia to other vital organs.The key objectives of the project are to validate safety and efficacy of the CAPTIS system through a First-In-Human clinicaltrial and multi-site clinical trial, and to obtain CE mark certification for commercialisation in Europe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Experiencing Historical Soundscapes: the Royal Entries of Emperor Charles V in Iberian Cities' (ExpSoundscapes).

assistant: **Concept**

This project aims at bridging the gap between describing, reflecting on, and experiencing historical soundscapes. It will integrate historical, sensorial, and artistic approaches so as to retrieve the soundscapes of Early Modern Royal entries in Iberian cities in the time of Emperor Charles V (1517-58). Sonic information will be extracted from coeval documentation to be analysed and organised in a database and georeferenced in a map through GIS technology. The sound data will serve as the basis to create an immersive multimedia event, where selected sonic scenes will be reproduced by engineered sound and live music. The spatial surroundings will be recreated through historical paintings and 3D renditions of selected urban spaces. The immersive event will be a highly distinctive experience, with the potential to transform the traditional understanding of historical events by introducing elements of sensorial scholarship. It will facilitate exposure of high-quality repertoire within specific historical events. Likewise, the project will explore new avenues of the possibilities that the use of digital technologies provides to the understanding of music historical subjects (as postulated by European policies such as 'Digital Futures') and its management as intangible heritage. This research will make academic impact at different levels. The most significant will be the establishment of a groundbreaking methodology to facilitate the experiencing of sensorial experiences of the past, drawing on a phenomenological perspective. It will provide complementary tools to the traditional understanding of historical soundscapes, fostering interdisciplinary collaboration that will bring together areas such as music, history, geography, performance, and technology. Ultimately, it will o