RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Low-cost, Green, Large Scale Manufacturing of new age conducting nanowires displays'.

assistant: **Concept**

Currently, display industries, LCD and OLED displays manufacturing is based on Indium-Tin Oxide (ITO) Transparent Conducting Films (TCF). Nevertheless, Indium metal is a very scarce material and its worldwide resources are becoming increasingly limited. Thus, the prices of  produced displays based on ITO will  inevitably rise day by day if no alternative material  is developed to replace  it. Moreover, ITO films have limitations in flexibility and this fact excludes them from application in the production of new-generation displays, such as electronic books and flexible displays.The guiding principle of NanoDiGree is to manufacture, through economical viable production methods, competitive high quality transparent conducting films in order to replace ITO. This projected solution will be based on the production of conductive/transparent inks containing Cu nanowires which will be fabricated via advanced pulse electrodeposition (PED) methods. The Cu nanowires will be electro deposited into anodised aluminium oxide (AAO) nanoporous-templates by utilizing pulse current electrodeposition. The produced nanowires will be dispersed in “green” solvent mixture in order to develop the printing inks for the afterwards production of the films. Finally, Roll-to-Roll printing will be used in order to apply thin flexible conductive-transparent films on suitable polymer substrates that will be used as the flexible devices.The goal of the NanoDiGree proposal is to intercept the trend of integration of all supply chain manufacturer of displays in Asia by producing high added value component in Europe. The successful outcome of this project will have a significant impact in European competitiveness within the market of TCF. Indeed, the impact is intended to be significant, considering that
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The world’s first Terahertz application for Inspection-As-A-Service: Ensure quality and reduce waste in industrial production through inline inspection' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Surprisingly, many high-added value and high-quality performance-driven industries such as automotive, aerospace, robotics, medical, and technical textiles rely on old-fashioned and manual inspection methods. Defects and contaminants are often detected only after production (end-of-line quality control) using cumbersome, slow and expensive X-Ray machines. This problem has a major impact on manufacturers and consumers as raw materials, production efforts and energy are irreversibly wasted due to this late and partial inspection. Moreover, due to the emergence and increasing prominence of high-performance composites cut across all fields – wind power (e.g. wind turbine blades), aerospace, automotive - effective and reliable production control and inspection techniques still remain incipient – most of the inspection techniques are still done in a visual and manual way (“market creation” opportunity).  Tulipz is a disruptive IoT plug & play solution for inline production and quality control, which combines a patented Terahertz (THz) technology with proprietary deep-learning algorithms deployed as a software-as-a-service (SaaS) platform. It allows for total real-time, distributed, non-destructive inspection (NDI) along production lines instead of the currently used end-of-line approach, thus guaranteeing quality, increased throughput and minimal waste. The estimated benefits to customers are substantial: a 5x increase in productivity, equipment uptime of 99.99% and a reduction in production waste by 5%. TiHive is a team of energetic, enthusiastic and disruptive entrepreneurs, industrialists and researchers who founded the company after ten years of advanced R&D. Our ambition is to become world leader in distributed inspection for high quality, performance engineered products
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Chromatin Immuno-Linked Ligation [ChILL]: A novel generation of biotechnological tools for research and diagnosis' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

The recent efforts to decipher the genetic code for several genomes represent outstanding contributions to science. However, the blueprint of the genome does not in itself explain the regulation of gene expression. Another regulatory code is encrypted in chromatin conformations and functions to regulate the accessibility of the primary genetic information. The terms epigenetics have been proposed to describe heritable changes in genome function that occur without change in DNA sequence.The EU has already invested efforts into this research area by supporting the network of Excellence called The Epigenome" and the integrated project HEROIC. In both of these instances, the Chromatin Immuno-Precipitation (ChIP) assay plays an absolutely pivotal role to decipher patterns of epigenetic marks that govern gene transcription. While the ChIP assay is a versatile tool, it suffers from low resolution and low sensitivity.These strong limitations of the ChIP method are overcome by the Chromatin Immuno-Linked Ligation (ChILL) method. ChILL will not only facilitate analysis of very small sample sizes, such as early embryos or diagnostic samples from patients suffering from a range of diseases, but also radically improve the resolution of the epigenetic marks. As proof of principle, the ChILL method has already been shown to be at least 100 times more sensitive that the regular ChIP assay. Since the ChILL approach also offers opportunities to examine simultaneous co localization of two or more factors on the same chromatin template, the epigenetic marks will be resolved in unprecedented detail.The ChILL method relates to the detection and localization of one or more molecules interacting with chromatin using nucleoproteic conjugates. The commercial impact of the ChILL method might cons
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Year 2000 European Mathematical Society Saint Flour Summer School On Probability Theory' (1998-2002) under Fifth Framework.

assistant: **Objectives**

The Saint-Flour Summer School on Probability Theory and Statistics is the most famous international school on this domain in the world. The first one was held in 1971, and there was one such school each year since. The year 2000 edition is a special one, since it is the thirstiest anniversary of the Saint-Flour Summer School, and the year 2000 is the International year of Mathematics. For this special edition, the Saint-Flour Summer School was labelled as Year 2000 Summer School of the European Mathematical Society.This school is especially intended for PHD candidates and confirmed searchers in probability theory and applications, as well as researchers from banks, dealing with markets and option prices, and researchers from industry dealing with statistical physics.This summer school, which lasts 17 days, is intended to provide: Three high level series of fifteen hours, giving a deep view of research in an advanced domain . Enabling European probability to meet, exchange and present their work in short lectures (40 lectures of 40 minutes each) . Facilitating exchanges between top level theoreticians and practitioners of probability theory and statistics and their applications in industry and finance.ftp://ftp.cordis.lu/pub/improving/docs/HPCF-2000-00018-1.pdf
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Identification of the critical RANKL sheddase and the role of RANKL in breast cancer and metastasis' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Diseases associated with bone loss, cancer, and bone metastases affect millions of people andresult in severe disabilities, pain, and premature death. The group of Prof. Penninger was the first togenetically show that the TNF-family molecule RANKL (OPGL, T RANCE, ODF) and its receptorRANK are key regulators of bone remodeling (Kong et al Nature 1999). RANKL and RANK areessential for the development and activation of osteoclasts and bone loss in response to virtually alltriggers tested. Inhibition of RANKL fu nction via the natural decoy receptor osteoprotegerin preventsbone loss in postmenopausal osteoporosis, arthitis, and infection-induced tooth loss. RANKL andRANK are also essential for the morphogenesis of a lactating mammary gland, which provided anevolut ionary rationale for hormonal regulation of osteoporosis (Fata et al., Cell 2000). SinceRANK/RANKL control calcifications, a hallmark of mammography screening for breast tumors, andclassical breast cancer pathways such as NFkB and CyclinDl are activated by RANKL, we proposethat RANKL-RANK have a role in breast cancer and metastasis of epithelial tumors. Preliminaryresults suggest that RANKL plays an essential role in the cell migration of epithelial tumor cells intobones and in vivo inhibition of RANKL/RANK signaling results in a marked reduction in tumor burdenin bones, but not other tissues. Tomoki Nakashima has recently found that membrane-anchoredRANKL works more efficiently than the soluble RANKL in in vitro osteoclastogenesis assays(Nakashima et al; 20 00). The essential enzyme that controls RANKL shedding and thus the biologicalactivities of RANKL has not been identified yet.We propose experiments 1. to identify specific molecules that control the shedding of membrane boundRANKL to soluble RANKL and gen eti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Romanian Action for Integrating, Networking and Strengthening the ERAPetru Poni Institute of Macromolecular Chemistry'.

assistant: **Innovation**

The strategic objective of the RAINS project (within the function of Integrating and Strengthening the European Research Area) is to raise the RTD standards in a specific research field not only nationally, but through ongoing cooperation, partnership and sharing of scientific/technical expertise with similar institutions throughout Europe. The overall objective of RAINS is to support the integration of a leading Romanian institute - the 'Petru Poni' Institute of Macromolecular Chemistry (PPIMC) - in ERA as a centre having a critical mass enabling it to spread excellence in knowledge-based multifunctional polymeric materials. Having identified areas requiring further improvement within the PPIMC, e.g., participation in Framework Programmes, research personne l and trained administrative personnel, S&T infrastructure, RAINS is aimed at adapting the research potential of the institute to wider societal and economic needs both at regional/national and European levels; strengthening the cooperation with region al/national and European partners; increasing the competitiveness and participation in FP projects; disseminating information and facilitating communication between various scientific, educational and industrial bodies in view of full integration into the ERA; increasing the attractiveness of the research careers for young people to reduce the 'brain drain'; promoting full integration of women into the socio-professional environment.To accomplish the objectives and to ensure the long lasting of RAINS result s, a set of specific measures have been defined. They are focused on hiring and training of young researchers and administrative personnel, improving work/life conditions, upgrading/renewing the S&T equipment, fully connecting PPIMC to national RTD env ironment and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Topological semimetals for ultra-efficient electrical interconnects' (TICON), addressing dissemination and exploitation.

assistant: **Impact**

Moore's law dictates that the number of transistors in a Si CMOS integrated circuit will double every other year through size reductions that result in improved devices with smaller footprints. However, smaller transistors and greater transistor density also requires smaller interconnect copper metal wires to connect billions of transistors together. The issue is that metal wires, in contrast to transistors, show degraded performance when reduced in size.  This has resulted in an interconnect bottleneck, i.e. the situation when overall circuit performance is determined by interconnect delays, rather than transistor performance, and is one of the most serious challenges facing CMOS scaling today. By 2030, the interconnect linewidth will reach below 10 nm. At that point, Cu shows exponentially increasing resistivity due to surface and grain scattering, which will result in significantly increased delays and power dissipation. The solution to this issue is to develop new interconnect materials with improved properties at technologically relevant dimensions. This is the goal of the TICON project.The long-term vision of TICON is to replace scaled Cu interconnects in CMOS technologies with topological semimetals, a class of materials where electrical currents are dominated by surface states that exhibit protection from scattering. Several experimental reports now exist showing the extraordinary scaling properties of such materials, indicated by a reduction (rather than increase) of resistivity, as the dimensions of the semimetal are reduced. In this project, we employ the latest understanding of the physical mechanisms that govern topological semimetal transport, chirality, correlation and surface state engineering, together with a focused effort to synthesize high-quality th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Imagine, Invent, Influence'.

assistant: **Innovation**

Research is far more than lab coats and test tubes – Researchers’ Night in Malta will welcome children, students, parents and professionals from all backgrounds to interact with researchers in an educational and entertaining night.Based on last year’s experiences and the impact reached, I3 will guarantee an attractive, well-balanced programme of activities focusing on scientific and educational issues together with fun and entertainment, giving a face and voice to our researchers to show their work and its benefits to us all.I3 aims to bring our researchers and scientists closer to more than 4,000 visitors in a relaxed and festive environment. The programme will explore the role of science and research in our everyday lives through fun competitions, interactive activities and exhibits, drama, concerts, informal dialogues on hot topics and exhibitions, sky observations - all aiming at attracting the broad public especially young people and those not specifically interested in research. Furthermore researchers will be provided with the opportunity to present their work to peers and to the broad public.All the activities will also be broadcasted live on National Television and media reports are also expected to cover the event.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'New approaches to the study of membrane-protein folding in vivo and in silico'.

assistant: **Innovation**

Membrane proteins are central players in many if not most cellular processes: cell-cell interaction, signal transduction, nerve conduction, small molecule transport, macromolecular trafficking, etc. A growing number of high-resolution membrane protein structures  provide important insights not only into function but also into the general structural constraints imposed by the lipid bilayer. In contrast, almost no information is available concerning how membrane proteins fold in vivo. Mainly, this is because of a lack of suitable assays to follow the folding process.  The main objective of this proposal is to develop a broad range of new methods, largely based on chemical-biology approaches combined with protein engineering, to study membrane protein insertion, folding, and assembly in vivo or under in vivo-like conditions. We will aim for quantitative studies whenever possible. Questions we will address include: What are the in vivo kinetics of transmembrane-helix integration? What are the energetics of membrane insertion of non-natural amino acid side chains with physico-chemical properties distinct from those of the 20 natural amino acids? What kinds of residue-residue interactions drive interactions between transmembrane helices and between membrane protein subunits? How should we best design and verify novel interacting transmembrane helices? Given the importance of membrane proteins in both basic and applied biological research, we expect that a deeper understanding of the molecular interactions that drive their folding and stabilize their structure in vivo will have a major impact across many areas of molecular life science.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Advanced Dissemination and VAlidation Network for Cities in Europe in Transport' to be submitted under Fourth Framework.

assistant: **Abstract**

The objective is to develop and operate the European Local Transport Information Service (ELTIS), which will be an interactive website and database about European sustainable local and regional transport. The aim of the information service is to provide a decisional-support tool for consultation by transport policy-makers and managers, operators and user groups. - to catalogue, disseminate and make publicly accessible current practices,- to raise awareness among transport policy makers and attract these potential users to the ELTIS website and database,- to facilitate exchange of experience across Europe,- to establish an additional framework for networking between local government officials at elected and management level in the urban transport field and transport operators and user groups.Links with other projects, tasks, areas, programmes, policy actions:Co-operation with the other relevant Directorates General of the European Commission (e.g. DG XI), creation of links to other EU web pages.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Multidisciplinary Quantum Gravity Studies'.

assistant: **Objectives**

A major problem of quantum field theory in curved spacetime, and quantum gravity more generally, is the lack of sufficient observational and experimental guidance. To address this issue I am proposing a multi- disciplinary approach to quantum gravity, using its possible connection to easy-to-access physical systems whose description is well-established — in theory and experiment — within other fields, such as quantum information, condensed matter physics, and hydrodynamics. This will allow me to address longstanding questions of semi-classical and full quantum gravity from a new perspective. In addition, I propose to engage the tools and concepts developed for the project’s objectives to further deepen the understanding of the non-gravitational systems evolved. In contrast to many other proposals, this programme’s objectives are both of theoretical and experimental nature, and range from a quantum information approach to quantum gravity to foundational studies on wave-current interactions.