RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Investigating if recuperating hepatic macrophage numbers and functions in chronic fibrosis can limit the incidence and severity of infections' under Horizon Europe.

assistant: **Concept**

Liver fibrosis is the build-up of scar tissue resulting in impaired liver function. It can have different causes including alcohol abuse, obesity and viral hepatitis. For reasons that we do not fully understand, patients with fibrosis (termed cirrhosis) are more susceptible to infections. In fact, 50% of hospitalized patients with liver cirrhosis and infection die, highlighting the scale of this problem. Macrophages (MFs) are immune cells present in every tissue of the body that function to eliminate pathogens. In the liver, one subset of MFs, the Kupffer cells (KCs) are perfectly equipped with scavenger and pathogen recognition receptors to do this. Moreover, they are positioned in the bloodstream meaning they are one of the first cells to sense and respond to circulating pathogens although their precise roles have not yet been elucidated. In cirrhosis, KCs are reduced in number, being replaced by distinct MF subtypes, including a population termed lipid-associated MFs (LAMs). Preliminary data from the host lab demonstrate that both KCs and LAMs from the cirrhotic liver respond less efficiently to infection when compared with their healthy counterparts. Thus, I hypothesize that the altered MF landscape in cirrhosis and fibrosis is one mechanism driving the increased susceptibility and exacerbated responses to infection in these patients. Here, I aim to test this hypothesis by examining how the different MFs respond to infection in the presence and absence of fibrosis. Using novel mouse models specifically targeting the distinct MF populations, coupled with ex vivo cultures of human hepatic MFs, I will tease apart the mechanisms through which MFs exert their effects and attempt to manipulate these to recuperate normal MF numbers and functions potentially uncovering nove
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'CARBon-negative COMpression dominant structures for decarbonized and deconstructable CONcrete buildings' (CARBCOMN) under Horizon Europe.

assistant: **Objectives**

CARBCOMN addresses a disruptive innovation in zero-carbon concrete load-bearing structures (combination of columns, beams, slabs or walls) by setting forth a new digital AEC design paradigm that is fully compatible with concrete that uses CO2 as raw material and is carbon-negative. Digital methodologies are exploited and developed to realise an innovative carbon-neutral construction system implementing structural geometries that are compression dominant, optimise the CO2 sequestration capability and make use of demountable discrete blocks combined with system redundancy. The latter will be assisted by the combined use of funicular shapes and post-tensioning with shape memory alloys. To handle the complex geometries in combination with a carbon-negative concrete-like material, an innovative digital pipeline is developed that incorporates for example computed tomography, topology optimization and 3D construction. Using CO2 sequestration to harden the concrete-like material for widely used load bearing structures will reduce embodied greenhouse gas emissions in an unprecedented way. The material design, incorporating recycled materials and by-products derived from other industrial processes (e.g. slags  and ashes) will equally reduce raw material usage. The intrinsic durability properties by introducing a system that is not susceptible to rebar corrosion and is deconstructable, will achieve both long service life and circularity, to further reduce the environmental impact of the built environment. The overall superiority of the proposed system with respect to the current state of practice will be demonstrated through a full life cycle analysis. Throughout the CARBCOMN project, compliance with relevant standards of building operational performance will be established, and d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Combinatorially and Algebraically Decomposing Search spaces: Better Worst-case Bounds for Hard Search Tasks' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Search tasks are computational tasks with a curious property: while their solutions are easily verifiable when given, finding those solutions from scratch appears much more arduous. A central algorithmic paradigm to solve such tasks is that of search space decomposition. This paradigm solves a search task by breaking it up in subtasks such that a solution to the original problem can be quickly recovered from solutions of the subtasks. Despite its basic nature and its ubiquitous use, it still holds many mysteries.The mission of COALESCE is to develop a broad theory to design and analyze search space decompositions to solve fundamental search tasks as fast as possible in the standard model of worst-case analysis. Strikingly, such a theory has not been developed yet. Our theory will be a coalescence of two established theories:- Combinatorial search space decompositions have been studied for graph problems in the area of width parameters, but only focus on decomposing the input and not the search space.- Algebraic decompositions such as factorizations of matrices and tensors that are of low rank or sparse, have been studied in the area of algebraic complexity, but only for very few problems and not in combination with search space decompositions.In this proposal, I identify concrete research problems from Parameterized and Fine-Grained Complexity (two prominent subfields of Theoretical Computer Science) that serve as stepping stones towards a model for search space decompositions beyond input decompositions, as well as a theory to analyse their algorithmic power based on combinatorial and algebraic decompositions.Now is the right moment for this project: the joint power of combinatorial and algebraic decompositions is still barely understood and not yet fully exploited. CO
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Vestibular and multisensory investigations of bodily self-consciousness' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Despite recent neuroscientific efforts to study the mechanisms of consciousness, self-consciousness has received much less attention as it is difficult to approach empirically. However, it has been argued that self-consciousness relies on several bodily experiences, and that the investigation of the sensory and neural mechanisms involved in these bodily experiences is crucial for the understanding of self-consciousness. Bodily experiences that seem necessary for the self comprise first-person perspective taking, embodied self-location, and the sense of ownership of the body and body parts. Multisensory processing has been proven to be of key importance for bodily experiences and the self, although research has focused mostly on the contribution of visual and somatosensory signals. The investigation of vestibular signals has received much less attention despite its key importance in coding whole-body motion and orientation in space. The BODILYSELF Project plans to investigate vestibular contributions to whole-body experiences, in particular self-location, first-person perspective taking and self-other distinction and mirroring. For this, vestibular physiology will be linked with neuroimaging and cognitive science of the self. We will use artificial stimulation of the vestibular system (galvanic vestibular stimulation) and multisensory conflicts – in combination with electroencephalography and fMRI – to explore the mechanisms of bodily self-consciousness. The strength and novelty of the BODILYSELF Project lies in joining approaches from cognitive neuroscience, vestibular physiology and oto-neurology, in collaboration with a philosopher of mind, for a common goal. This may lead to findings that are relevant across research fields in the cognitive neurosciences of the self,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'High Luminescence In Cockpit'.

assistant: **Objectives**

Although the market demand of displays bright enough to allow the diffusion of readable information against a very bright landscape is important, in particular in the avionics application, existing technologies still do not allow the desired brightness combined with very low power consumption and very compact volume.In this context, the HiLICo project aims at developing a new generation of monochrome and full-color emissive GaN micro-displays with 1920 x 1200 pixel resolution (WUXGA), 8-μm pixel pitch, very high brightness (over 1MCd/cm²) and good form factor capabilities that will enable the design of ground breaking compact see-through system for next generation Avionics applications.To achieve this aim, HiLICo will address the following challenges:1. development of high-quality GaN based LED epilayers designed to fulfill targeted demonstrator performances;2. design and fabrication of an active matrix in advanced Complementary metal oxide semi-conductor (CMOS) technology to control each individual pixel;3. coupling of the LED structure and the CMOS, building a monolithic structure on which LED arrays will be fabricated with high precision, thus making monochrome, active-matrix, high-resolution GaN microdisplays;4. addition of colour converters (quantum dots and 2D Multi-Quantum Wells layers) on such blue emitting devices, for fabricating bi-color and full-color display demonstrators;5. design and manufacture of the electronics followed by the test and evaluation of the complete micro display device. First demonstrators will be qualified for future commercialisation.The technology developed will contribute to the increase of European competitiveness, through the rapid and important deployment of innovative products on the microdisplay market, as well as Head-Up Display
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'SUPPORTING MOBILITY IN THE ERA THROUGH AN INTERNATIONAL FELLOWSHIP PROGRAMME FOR DEVELOPEMENT OF BASIC RESEARCH IN POLAND' (POLONEZ) targeting Horizon 2020.

assistant: **Abstract**

POLONEZ is a Fellowship Programme supporting international incoming researchers working in the broad field of research regardless of their nationality. It will be implemented by the National Science Centre (NCN), a government agency funding basic research in Poland. The NCN has already designed 11 funding schemes supporting researchers on every stage of their research career and regularly announces calls for proposals. The Centre is also involved in international funding initiatives, e.g. ERA-nets, JPIs. It follows a strictly bottom-up approach, allowing researchers to freely choose their research topic and host institution. POLONEZ, planned for 69 months, enables the NCN to implement 3 calls for proposals in order to select 90 fellows. It is targeted at experienced researchers who may apply for 12-24-month-fellowships in host institutions in Poland, both academic and non-academic, public or private. Apart from living, mobility and family allowances, they are offered a research grant which amounts to ca. € 4 200 per month, to cover the costs of a research project in a discipline freely chosen by the applicant. The fellows are also given an opportunity to participate in a variety of research and non-research trainings provided by the NCN and the host institution. One of the main goals of POLONEZ is to enhance incoming mobility in Poland. Although Polish host institutions offer an attractive research setting and high quality resources, fellowships in Poland attract fewer researchers. Also, many Polish researchers still seek temporary and permanent positions outside of Poland and Europe. Therefore, in order to counteract “brain drain,” build up a positive image of Polish research institutions and encourage foreign researchers to develop their careers in Poland, we offer th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Phenomics and evolution of sexual dimorphism and female colour polymorphism in damselflies' (PhenoDim).

assistant: **Concept**

During over 100 years of ecological and evolutionary research, the study of colour polymorphisms has helped to improve our understanding of phenotypic diversification in nature. Polymorphisms are typically expected to be maintained within local populations by evolutionary processes, such as negative frequency-dependent selection. Yet there are only few studies that have quantified multiple axes of correlated phenotypic variation in addition to colour, which limits our current understanding of the emergence and evolutionary maintenance of genetic colour polymorphisms, for example, via correlational selection, linkage or pleiotropic effects. To address this long standing issue, I here propose a series of research projects that use computer-driven high throughput phenotyping to conduct comprehensive phenotypic analyses (phenomics) of a sexual dimorphism and female-limited colour polymorphisms in damselflies (Odonata; Zygoptera). The overarching goal of these projects is to investigate if and how much female damselfly colour morphs that mimic male colouration to increase their fitness (androchrome females) also vary in other, potentially correlated phenotypic traits, such as morphology, behavior and development. First, I will analyze an existing image data set of evolutionary time series data of Swedish damselfly populations, using a combination of classic computer vision and deep learning algorithms to quantify axes of phenotypic variation that have not yet been investigated. Second, I will conduct a mesocosm experiment using individuals from the same local Swedish damselfly populations to investigate whether androchrome females show alternative developmental trajectories. Third, I will conduct in-depth phenotyping of an existing image dataset of different damselfly specie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The origin of the IMF through multi-scale analysis of molecular clouds: unification of PDF and power spectrum analysis' (2014-2020).

assistant: **Concept**

The omnipresence of filamentary structures inside nearby molecular clouds observed by the Herschel space observatory challenges our comprehension of the star formation process. We now know that most of the cold dense cores appear to form within those filaments, which suggest a possible link between the characterisation of the filamentary structure of molecular clouds and the core mass function (CMF). Physical processes such as turbulence, gravitational fragmentation and the influence of magnetic field transform the interstellar medium and leave characteristic signatures within the shape of structures. In order to understand the physical processes leading to the formation of filaments and cores in molecular clouds and later to the formation of stars, many statistical tools have been developed to characterise such signatures. Among them there are the probability distribution function (PDF), which form the foundation of many modern theories of star formation, and the power spectrum analysis, which started with the pioneer work of Andrey Kolmogorov and remains our best tool today to analyse and characterise the turbulence. Usually measured independently, I propose in this project to unify both analysis through a multi-scale analysis approach of nearby molecular clouds. In the recent years, I developed wavelet based analysing techniques allowing me to separate the different statistical signatures of physical processes involved in filaments and cores formation. Furthermore, part of these techniques also imply the analysis of linear polarisation allowing a unique multi-scale description of the interstellar magnetic field. The aim of this project is to build a global and coherent picture, based on observations, of how cloud structures and magnetic fields have an impact on the f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'RACE: ERA Chair Initiative for Establishing a Research and Innovation Program of Excellence on Ageing and Longevity at UoC'.

assistant: **Innovation**

The University of Crete (UoC), starting from humble beginnings, has evolved into a globally recognized institution. However, in competitive fields such as ageing research, UoC faces substantial challenges, including disparities between regional and European approaches, limited training programs, insufficient access to skilled personnel, and budgetary constraints that impede sustainable research and innovation excellence on-site. To address these pressing needs, UoC aims to recruit and fully integrate a distinguished ERA Chair with world-renowned expertise in science and management related to ageing research. The ERA Chair holder will establish the interdisciplinary research program, ""RACE,"" as a unit of excellence dedicated to maximizing UoC's competencies, capacities, and expertise in ageing research. The RACE team will leverage UoC's state-of-the-art infrastructure, human capital, and expertise to address a major research topic with significant health-related and socioeconomic impact, building upon a well-structured, multi-disciplinary research program. The proposed ERA Chair initiative seeks to recruit and fully integrate the ERA Chair holder and the RACE team, enhance UoC's research capacity in ageing research, strengthen human capital through training in both research and soft skills competencies, increase competitive funding, and counteract brain drain for sustained development. Additionally, the initiative aims to foster innovation at UoC, enhance the management and administrative skills of the institution, leverage existing EU-funded infrastructures, and elevate the reputation of UoC through a comprehensive range of dissemination and outreach activities targeting the academic, private, and public sectors. Overall, RACE presents a credible path to fundamental s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Epidemiological studies for control of clavibacter michiganensis subsp sepedonicus, the causative agent of bacterial ring rot in potato' in the context of a Fourth Framework call.

assistant: **Objectives**

Clavibacter michiganensis subsp. Sepedonicus (Cms), the causal organism of bacterial ring rot of potato, poses serious economic risks to the potato industry within the EU. The current ring rot outbreaks in the different countries of the EU cost circa 15 MECU per year due to eradication campaigns, increased research and development and compensation to growers. Epidemiological data required to control bacterial ring rot once established are lacking. This project lays the scientific basis for the development and improvement of measures for control and eradication of Cms. In the first year the instruments will be developed to enable detailed epidemiological studies. This will include the selection of a representative panel of Cms strains, for which the genetical and phenotypical diversity will be assessed with fatty acid profiling, biolog, DNA fingerprinting methods and by testing the aggressiveness. To track Cms in complex natural environments, marked strains will be developed, including antibiotic resistant strains and strains marked with a luciferase or green fluorescent protein. Cultivation based and modern non-cultivation based methods, such as PCR-amplification, targeting DNA, and NASBA-amplification, targeting RNA, will be adapted and fine-tuned for reliable detection of Cms. In the next three years, complementary microcosm studies and field experiments will be done, determining the persistence, growth and dissemination of Cms in the potato cropping ecosystem under various environmental conditions. The fate of Cms in soil and water and the risk for infection of the potato crops from these infested substrates will be assessed. The survival on potato tuber surfaces will be determined and the internal colonization, in in vitro potato plants, minitubers and seed potatoes