RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Active Pressure, Position and Temperature sensors for Turboshaft engines'.

assistant: **Innovation**

ActiPPTSens consortium will established the technology benchmark on smart sensors for pressure, position and temperature measurement, based on the specification of NEWAC, DREAM and TEENI. Sensor technologies and their main features will be analysed and captured into a Sensors Technology Comparative Matrix, after the specification definition. The promising sensors technologies will be chosen for the prototype development. ActiPPTSens project have been structured as follow: Specification definition- The specification will be based on the public deliverable of project NEWAC, DREAM , VITAL and TEENI (new turboshaft concept) and TURBOMECA guideline as leader of the SAGE5 ITD; Benchmark of technologies- analysis of the existing technologies in the sensors field. Emerging or critical sensors technologies of several sector will be consider; and Prototype fabrication- Smart sensors prototypes of the selected technologies will be fabricated for their test in IDT SAGE 5 demonstrator. The initial technologies that the ActivePPTSens consortium considers as potential candidates for the prototype fabrication are: -Contactless Torque Sensor CTS, develop and patented by CEDRAT as technology was initiated for PSA. The CTS Contactless Torque Sensor measures the torque and the rotation speed of either a stationary axle or a rotating shaft without contact. -Piezoelectric MENS sensors, underdevelopment by INASMET-Tecnalia and ICV-CSIC. Piezoelectric sensors based on electrospun PZT nanofibers show higher pressure sensibility, longer life cycle, easy integration under structural elements and complex geometrical shape capability. -FBG devices, Fibre Bragg Grating technology with high embedding capability is under study for rotor blades or disks for the monitoring of aerial vehicles engine. The
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Precision Measurements of Fundamental Constants' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The fine structure constant α, the masses and magnetic moments of elementary particles like the electron or proton, and others are fundamental quantities which determine the basic structure of the universe. They can not be predicted by theory, but their precise determination is required to enable the comparison of theoretical models with experimental observations at the highest possible level. The improvement of these quantities beyond the present level of accuracy represents a significant challenge for modern metrology. We propose ambitious experiments and measurements to substantially improve the precision of a number of fundamental constants, namely the electron and proton mass, the fine structure constant α, the magnetic moment of the proton and of the bound electron, and the Q-value of the 3H-3He decay for an improved sensitivity limit in the determination of the electron-antineutrino rest mass. Using single-ion storage in a well-defined small volume with perfectly controlled electromagnetic fields for nearly unlimited periods of time, we will measure the eigenfrequencies of the particles with unprecedented precision in dedicated Penning traps. From those values, fundamental properties such as the magnetic moment, atomic and nuclear mass or, equivalent, binding energy can be extracted. This will reveal the strength of all interactions present in the quantum mechanical system. Our new results combined with established theories will yield values for fundamental constants like the electron mass and the fine structure constant α.  In order to meet these challenges novel trap geometries, ultra-sensitive and low-noise single-ion detection techniques will be developed and combined with other technological advances in order to enable us to reach up to one order of magnitud
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'High Performance Lewis Acid Organocatalysis' (HIPOCAT) targeting Seventh Framework.

assistant: **Abstract**

Although the demand for chiral enantiomerically pure molecules as pharmaceuticals, agrochemicals, and liquid crystals is growing strongly, the use of asymmetric catalysis for their production is rare. The most common industrial method to produce enantiopure compounds is still chiral resolution, which wastes half of the material. This surprises considering that catalytic methods are potentially cost-, energy, and resource-saving, have a lesser impact on the environment, and are in line with the general concepts of green chemistry and sustainability. Recently organocatalysis has grown into one of three fundamental classes of asymmetric catalysts complementing metal- and biocatalysis.  In principle, organocatalysts have many beneficial features such as air and moisture stability, non-toxicity, and easy accessibility, making them attractive for industrial applications. However, most organocatalysts are insufficiently active and require high catalysts loadings, counterbalancing these positive features. Remarkably, of the four types of organocatalysts, Brønsted bases and acids, and Lewis bases, and acids, organic Lewis acid catalysts have been almost entirely ignored. Very recently though, within the group of the applicant, the finding was made that such catalysts can be extremely active and enantioselective, suggesting the possibility for truly high performance organocatalysis. This proposal therefore aims at the design of novel organic Lewis acid catalysts, their exploration in asymmetric catalysis, and their mechanistic understanding. The program is expected to lead the way towards the next generation organocatalysts, which will rival the efficiency of the most active metal- and biocatalysts, and have the potential to profoundly change the way chiral molecules are made.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Efficient microgeneration combined with food cooling systems in trade, crafts and service companies' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

The project intends to commercialise an efficient microgeneration technology combined with food cooling systems in trade, crafts and service companies.The innovative core of microgeneration is an ORC cycle operating with a significantly lower inlet temperature of less than 60°C that allows for utilising heat from cooling systems  that have not yet been used due to the absence of an applicable technology. The system offers higher electrical efficiency and higher flexibility to different inlet temperatures than comparable systems. This opens a tremendous range of new applications opportunities of distributed, sustainable electricity generation based on recovering waste heat. The μORC system offers the unique opportunity to implement microgeneration in target markets with cold food storage, incl. food processing, food and beverage retail and service providers, and accommodation, which are producing considerable amounts of waste heat and which are potentially counting for ~10 % of the energy consumption in Europe. The commercial potential corresponds to 2.5 million installations in Europe at the moment.The feasibility assessment shall prepare the commercialisation of the super-low temperature ORC based μCHP system and elaborate a detailed business plan. In particular it defines a roadmap for further product development and identifies market areas and the specific target groups. The study investigates the details of customer needs and expected market structures, proves the technical and economic viability of the technology and prepares technical requirements, product documentation and data sheets.The developed technology directly contributes to European societal challenges such as reducing the consumption of fossil resources and the emission of greenhouse gases and it facili
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Ischia Advanced School of Organic Chemistry - 11th Session: Creativity in Organic Synthesis, from Target to Function' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

The main goal of the proposed Conference IASOC 2004 is to bring together the best, most innovative investigators in the various fields of synthetic organic chemistry in order to debate the latest developments of the following topics:(i) homogeneous catalysis, with emphasis on enantioselectivecatalysis,(ii) combinatorial chemistry, applied to both drug and catalyst discovery/optimisation,(iii) synthesis of complex bioactive compounds, both from the academic viewpoint and from the industrial perspective,(iv) bioorganic technologies.IASOC 2004 is based on an extremely timely project and the number of prominent scientists from all-round the world who are being invited (see Annex B2.1) to illustrate the most up to date discoveries in the selected topics will guarantee the success. There is no doubt in our mind that IASOC 2004 will be a major scientific event that will maintain, and even exceed, the high quality of previous IASOCmeetings, offering the young European Chemists an invaluable opportunity to improve their own knowledge in organic synthesis and related disciplines. They will have the opportunity to come in contact with senior researchers, who are worldwide recognized experts in the topics selected for the exciting programme of the proposed Conference IASOC 2004.During five working days, they will be exposed to the most up to date developments in the above topics that will be presented extensively and examined from different viewpoints and perspectives. Discussion will be promoted in order to foster the best profitable flow of information between young researchers and leading scientists, with the aim to acquaint the formers with the benefits but also with the limitations offered by novel methodologies and recent breakthroughs in synthetic organicchemistry. Such exch
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Flexible Gateways Architecture for enhanced access network services and applications' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

The main objective of the FlexiNET project is to define and implement a scalable and modular network architecture incorporating adequate network elements (FlexiNET Node Instances) offering cross-connect control, switching/routing control, and advanced services management/access functions at the network access points that currently only support connectivity between user terminals and network core infrastructures. The primary aim is not to replace or enhance existing networking infrastructures, but to offer a value-added complementary network architecture addressing service access de-centralisation and separation of data, service logic and control from the pure transport network.The FlexiNET architecture will be based on the FlexiNET node instances, which will consist of scalable hardware and software platforms on top of which core network functionality will be realized, as a set of distributed sub-systems integrated into a generic services execution environment. The FLEXINET concepts and architecture are applicable to various access network technologies (GSM/GPRS/UMTS, WLANs, V5, etc.), but will be focused on the mobile and wireless operator needs (UMTS and WLAN) for packet switched applications.The basic motivation for this project is to relieve core networks from data handling and signalling procedures overhead, to accelerate the introduction of next-generation marketable services, and increase competitiveness in the telecom field by facilitating the broadening of current business models for services provisioning and exploitation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Continuous Resolution and Deracemization of Chiral Compounds by Crystallization' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Industries are in need of highly skilled academically trained experts and powerful sets of tools enabling the design, control & prediction of optimized & efficient production process of future high-value products such as chiral pharmaceuticals. The CORE Network will in parallel train 15 ESRs and develop tools, approaches and methods within the area of Continuous Resolution (CORE), the process to obtain enantiopure molecules of chiral compounds.The training objective of the CORE network is to deliver a CORE skills toolbox of knowledge, personal, organizational and impact skills to a core of multi-disciplinary scientists and engineers in the interdisciplinary and cross-sectional field of Continuous Resolution. Each ESR obtains dedicated training through their research project, network events, a webinar course, management involvement and an academic & industrial secondment.The research objective of the CORE Network is to jointly construct a CORE Industrial Toolbox on Continuous Resolution that provides next generation tools, approaches and methods to industry for the development continuous resolution processes. The strongly involved industrial partners will ensure that the CORE Industrial Toolbox fulfils their requirements in the skills gap areas Towards Continuous, Hybrid Resolution and Enabling Resolution. CORE brings together 8 academic and 7 industrial partners resulting in an unparalleled combination of chirality, synthesis and crystallization training and research covering the areas of Chemical Engineering, Chemistry and Applied Physics.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'RRI TOOLS, a project to foster Responsible Research and Innovation for society, with society.' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

This project will develop and use a Training and Dissemination Toolkit on Responsible Research and Innovation (RRI). It will be addressed and designed by all the stakeholders of the Research and Innovation (RI) chain of value, including Researchers, Civil Society, Industry and Education but will specially focus on Policy Makers in order to impact significantly in the future governance of RI.The Consortium that will carry out the project is a 26 multi-stakeholder group of institutions with experience in different key components of RRI. The project envisages the creation of 19 RRI Hubs covering 30 countries of the European Research Area. The Consortium and the RRI Hubs will carry out a process of development of the toolkit that will be collaborative and inclusive, this way fostering methods and channels of dialogue in order to increase creativity and shared ownership of the process. Ultimately, the process will lead to a Community of Practice in RRI which will assure the use, evolution and enrichment of the toolkit.The RRI Toolkit will be an innovative and creative set of tools comprising practical digital resources and actions aimed at raising awareness, training, disseminating and implementing RRI. The RRI Hubs will be responsible for training on the use of the toolkit throughout Europe, of advocating policy makers at a national and regional level and of disseminating the concept of RRI to a wide audience.Bridging the gap between Science and Society has been a challenge for decades. Today, there is evidence that we need to involve wider society in decisions about the form and direction of research and innovation to contribute to a smart, inclusive and sustainable growth of our societies. RRI TOOLS will help transform Research and Innovation in Europe into a process targ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Development of nickel free titanium based shape memory alloys for biomedical applications' to be submitted under Fourth Framework.

assistant: **Abstract**

Continuing advances in the areas of clinical science involving the use of implants inside the human body have created demand for materials that need to satisfy the twin needs of bio-compatibility and special material properties such as the shape memory effect and superplasticity. Titanium-Nickel based alloys possess the aforementioned properties and their use is rapidly gaining acceptance. Nickel however, is well known to cause adverse effects to the body by a process of nickel migrating into the blood stream Although bio-compatibility tests have not detected any adverse effects by completely removing nickel from shape memory alloys would eliminate the chance of any toxic effect. This development would produce an alloy which is more attractive to the medical profession and increase the use of titanium-based memory alloys in new applications such as implanted drug delivery systems, endoscopy, laproscopy etc. It is proposed that the elements unlike nickel, such as; zirconium, niobium, tantalum and platinum which are essentially bio-compatible, will be alloyed with titanium individually or in combination can also exhibit the shape memory effect. The research is required to identify suitable alloys from this group which would have all the beneficial shape memory effects of the titanium-nickel based alloys and also reduce adverse biological responses. At present 2 SME' have agreed to co-operate in this research programme, on from the Netherlands and one in the UK. Further European partners will be sort during the exploratory phase of this programme. The SME's lack the research facilities and skills necessary to carry out the materials research aspects of the programme and this component of the work will be carried out by the Defence Research Agency base in the UK and the Fre
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Promoting RObust Systems biology on Patients and Experimental models with obesity-driven liveR cancer', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

In obesity, pathological expansion of adipocytes leads to increased adipose tissue macrophage (ATM) amounts and adipocyte death. Adipocyte death in turn is linked to ectopic lipid spillover and metabolically triggered inflammation which is a risk factor for diseases such as cancer, particularly hepatocellular carcinoma (HCC) that is linked to nonalcoholic steatohepatitis (NASH). Hepatic fat accumulation leads to chronic hepatocyte metabolic and oxidative stress resulting in cell damage and death. Although oxidative damage, microbiome dysbiosis, mitochondrial dysfunction, sterile inflammation are important in promoting NASH and fibrosis and cirrhosis are crucial for HCC development, the exact trigger(s) remain unknown. In HCC tumor cells take up nutrients, including lipids, to support their proliferation and solid tumors in HCC are characterized by enhanced hypoxia and acidosis resulting from a locally modified metabolism. Beyond malignant cells, the tumor-microenvironment (TME) contains immune cells including tumor-associated macrophages (TAMs) and dendritic cells. TAMs are pro tumorigenic, sabotaging anti-tumor immunity through various mechanisms. Notably, TAMs’ tumour-suppressive phenotype is directly linked to their lipid loading and disrupting lipid formation in TAMs attenuates tumor growth. Further, in the TME, dendritic cells are triglyceride laden, which contributes to immunosuppression by impairing their ability to present antigen. Despite advancements, a systems approach to understand the exact metabolites and lipid species in obesity driven HCC remains a challenge. Moreover, which metabolites are adipocyte-derived or locally produced within the liver remains unclear. Here using systems biology, coupled to NASH and NASH driven HCC animal models as well as patie