RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Toxicogenomic studies on engineered carbon nanomaterials' in the context of a Seventh Framework call.

assistant: **Objectives**

Engineered nanomaterials (ENM) are becoming an issue of great concern regarding their health effects. Different types of ENM are being used today in everyday consumer products as well as professional equipment such as medical devices. Several ENM, even those used in products that are already on the market, have been shown to be cytotoxic, genotoxic and immunotoxic in experimental settings, but knowledge is still too scarce and inconsistent for efficient and accurate risk assessment on ENM exposure and the materials are still classified according to the toxicity of their respective bulk material. Carbon nanotubes (CNTs) are among the most utilized ENM and studies have indicated that certain types may have similar health effects as the well-known human carcinogen, asbestos.The toxic effects of CNTs have been investigated at several levels, but the genetic mechanisms behind these effects are still largely unknown. Toxicogenomics investigates the multifaceted genomic responses to xenobiotic substances in biological systems on a genome-wide level. Thus, toxicogenomic studies may reveal the genomic changes related to CNT exposure and may give insight into the mechanisms behind their hazardous effects.In this study genetic features such as mRNA and microRNA expression changes as well as histone modification patterns will be profiled on a genome-wide level in a bronchial epithelial cell line following exposure to various carbon nanomaterials, including CNTs. Asbestos will be used as a positive control. This will enable the identification of early genomic changes which may elucidate the mechanism of action behind the cellular responses to these ENM and possibly reveal eventual toxic outcomes following exposure. Furthermore, the results are anticipated to lay a foundation for acc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Improvement and sustainability of box production’s process for e-commerce' (FASTBOX) under Horizon 2020.

assistant: **Objectives**

Panotec’s a dynamic company in north-east of Italy founded in 1986 when it created and patented an innovative and flexiblesystem for producing corrugated cardboard boxes at the customer site. Each system was designed to be able to provideboxes and packaging materials for products that widely vary in size, material and configuration. Panotec has a worldwidedistribution base. Customers that use Panotec equipment are able to reduce packaging costs and inefficiencies bybypassing the normal supply chain for corrugated boxes. The project that Panotec’s going to develop is about a system forproducing boxes for e-commerce sector. Nowadays more and more people buy products with e-commerce and theseproducts must be prepared for shipping in as short as possible time to satisfy consumers and boxes should protect theproduct inside. The objective that Panotec wants to reach is to improve the actual process of boxes production, also from thepoint of view of environmental sustainability. The system which will be developed will ensure the automatic optimization ofbox dimension, minimize volume of packaging, reduce use of raw material due to the automatic optimization of dimension,reduce use of non-recyclable material, reduce time for preparing box for shipping, increase safety of products. From thepoint of view of environmental sustainability, the system allows to obtain boxes without fillers, that could only become nonrecyclablegarbage, and so the end-consumer will have only boxes 100% recyclable. The system will give also benefits forlogistic with elimination of inventoried boxes of different types, and for management and costs of warehouse. It will also bepossible to produce a box when it needs and for every kind of different products, adapting dimensions on it. This projectwould lik
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Bio-inspired capillary capture of viscous fluids with soft structures.' to be submitted under Horizon 2020.

assistant: **Abstract**

Capturing fluids at small scales is a challenge that nectarivores have solved by developing various type of specialized tongues, which consist of a complex assembly of flexible structures of small size compared to the capillary length. Most of the physicochemical mechanisms allowing some of those animals to quickly feed on nectar are not yet fully understood. This project aims to understand the physical mechanisms underlying the efficient capture of nectar by bees and hummingbirds which results from the dynamical coupling between viscous flows, capillary forces and elasticity in hierarchical soft tongues. To achieve this objective, model experiments are proposed. Mimicking hummingbirds’ tongues, I will first characterise the static closing of soft open tubes in contact with a specific amount of liquid. I will then study the dynamics when the same structure is dipped and removed from a fluid bath. In a second step, I will study the equilibrium shape and the dynamics of soft brushes and hairy surfaces dipped into a fluid bath, mimicking bumblebee’s tongue. The study of these systems will allow us to develop general physical models. The relevance of these models for describing the biological systems will be assessed by the direct comparison between the theoretical predictions and in-vivo measurements by setting the control parameters of the model systems to values compatible with the biological systems. This project will thus provide general models for the capture of viscous fluid through elastocapillary effects in some geometries inspired by biological systems.Based on the insights gained from these model experiments and the comparison with in-vivo data, optimal soft structures will be designed to passively capture precise amount of viscous fluids at a controlled rate. Th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Conserved develoPmentaL trAjectories chaNnelling laTeral root prImorDium morphogenesis' in the context of a Horizon Europe call.

assistant: **Objectives**

The root system anchors the plant to the ground and absorbs water and nutrients to sustain plant development. Understanding root development and its adaptative behaviours to changing environments is a major goal of the 21st century. This interdisciplinary project aims to identify a conserved developmental program between a non-domesticated model plant, Brachypodium, and a cultivated legume crop, Lupin. Secondary root formations such as lateral root (LR) and cluster root (CR) are significant contributors to the adaptative nature of the root system’s architecture. This work will initiate five new collaborations and reciprocal expertise transfers that will benefit both the host labs and the researcher. Preliminary results from the hosting labs showed that Brachypodium LR and Lupin CR organogenesis share common developmental stages. The objectives of PLANTID are (i) investigating the developmental trajectories of LR cells in Brachypodium and (ii) identifying key cell wall (CW) regulators required for LR/CR development in Brachypodium and Lupin. The first phase of PLANTID will be conducted in the Laboratory of Cell and Molecular Biology at the University of Neuchâtel (CH) and the second phase at the IPSiM (Institut for Plant Sciences of Montpellier), Montpellier (FR). The two research labs have complementary experiences in the root development of those organisms. Secondment at MPIMP Laboratory in Potsdam will generate the first CW atlas in LR morphogenesis for the two species. I will lead this fellowship with my strong expertise in CW biology and LR development. I will identify genetic regulators that impact nutrients and water uptake with a high potential for agricultural applications in cereal species (e.g biofuel and crop productivity). The project objectives support the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Towards the era of personal services at home and everywhere' (EPERSPACE), addressing dissemination and exploitation.

assistant: **Impact**

European citizens own a large number of devices with different capabilities ranging from TV to smart phones, PCs or set-top boxes. The ability to exchange data and access external services from these devices is limited which severely hampers the effectiveness of personalisation. This in turn affects the usability and thus mass- market adoption of advanced audio-visual networked services.The ePerSpace project addresses the major challenge to make it happen". ePerSpace project aims at significantly increasing the user acceptance of networked audiovisual systems and applications at home and virtually anywhere by developing innovative personalised value-added networked services. With the integration of the telecom global networks and the home audiovisual and networking sectors, ePerSpace will solve existing interoperability problems in personalisation data exchange, services, context adaptation and management of service platforms.From a social and business perspective, ePerSpace will develop user adoption and business models focussing on mass- market services enabling seamless cooperation of multimedia user platforms and devices to access anywhere personalised services. Dissemination activities including trials, user surveys and demonstration will be instrumental for that purpose. ePerSpace objectives will be realised through 4 major work areas:-The Home Platform providing the means to exchange audiovisual content between user terminals and home equipment-Global Network Integration and Interoperability offering innovative seamless access by sharing user profiles in a secure manner-Home and Personal Devices building unified personal environments-Rich Media Object Management supplying the tools for content creators to make optimal use of the infrastructure. ePerSpace will sta
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'An In-depth Look at Nanoplastics and Antibiotic Resistance' (NPLAMR) under Horizon Europe.

assistant: **Objectives**

Antimicrobial resistance (AMR) and plastic pollution are among the top ten emerging global challenges identified by the United Nations Environment Programme, posing significant threats to environmental health. Recent studies suggest that nanoplastics (NPs) can penetrate bacterial cells and potentially enhance horizontal gene transfer (HGT) of antibiotic resistance genes (ARGs) in the environment. However, the mechanisms by which NPs invade bacteria, and the potential for reversing this process, remain unclear. Therefore, the NPLAMR project aims to identify the types of NPs that most contribute to the emergence and spread of ARGs, determine the size threshold of NPs capable of penetrating antibiotic-resistant bacteria, and elucidate the mechanisms of NPs invasion and their roles in the propagation of AMR. The project will qualitatively detect NPs in environmental samples and quantitatively assess key NP types, ARG classes, and mobile genetic elements that facilitate the spread of ARGs. Through culture experiments, NPLAMR will determine the size threshold of NPs capable of invading antibiotic-degrading bacteria and evaluate potential hazards by analyzing changes in the resistome, mobilome, and metabolome of these bacteria. Finally, microcosm experiments will co-culture NPs with environmental microbial communities, isolate invaded microbes, and assess their HGT rates to determine which antibiotic-resistant bacteria are most affected by NPs. The cutting-edge metagenomics and bioinformatics facilities at ICRA (the host), along with its specialized expertise, will enable the fellow to become a leading expert in microbial ecology. The project will present its findings in an accessible way to raise public awareness about plastic waste and AMR, thereby increasing attention to en
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Flow Simulations On-demand Using Grid Computing'.

assistant: **Innovation**

The aim of the proposed FLOWGRID project is to establish a CFD Virtual Organisation, by setting up a GRID infrastructure and by deploying and sharing, software, computing resources and knowledge. FLOWGRID is an example of a GRID computing environment, with the vision to revolutionise the way CFD simulations are set up, executed and monitored on geographically and organisationally dispersed computing resources. This will be achieved by using a novel CFD solver and the expertise of the consortium in CFD, GRID computing and distributed computing. The project is generic and the components developed will allow their deployment on most European and International GRID. Information dissemination and liaison with other GRID projects will be established.The FLOWGRID model and software will be commercialised at the end of the project.OBJECTIVESThe specific measurable objectives of the FLOWGRID project are:- To establish a network of GRID-enabled CFD centres from different European countries;- To develop and implement novel client software for accessing CFD solutions on the GRID;- To develop scalable and generic middleware to support the deployment of CFD solvers on the GRID;- To assess the performance of the parallel version of the CFD solvers, by running real industrial applications on parallel distributed computers;- To validate computational results with experimental results;- To liaise with other European GRID projects.DESCRIPTION OF WORKThe FLOWGRID software will be built on existing technology for GRID computing (GLOBUS) and use an EJB architecture (and J2EE) to support the deployment of CFD solutions on the GRIDvia a Java client.The work to be carried out, in order to develop the FLOWGRID components, their integration on the FLOWGRID testbed, and their evaluation, will incl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'An investigation of the mechanisms at the interaction between cavitation bubbles and contaminants' (CABUM).

assistant: **Concept**

A sudden decrease in pressure triggers the formation of vapour and gas bubbles inside a liquid medium (also called cavitation). This leads to many (key) engineering problems: material loss, noise and vibration of hydraulic machinery. On the other hand, cavitation is a potentially a useful phenomenon: the extreme conditions are increasingly used for a wide variety of applications such as surface cleaning, enhanced chemistry, and waste water treatment (bacteria eradication and virus inactivation).Despite this significant progress a large gap persists between the understanding of the mechanisms that contribute to the effects of cavitation and its application. Although engineers are already commercializing devices that employ cavitation, we are still not able to answer the fundamental question: What precisely are the mechanisms how bubbles can clean, disinfect, kill bacteria and enhance chemical activity? The overall objective of the project is to understand and determine the fundamental physics of the interaction of cavitation bubbles with different contaminants. To address this issue, the CABUM project will investigate the physical background of cavitation from physical, biological and engineering perspective on three complexity scales: i) on single bubble level, ii) on organised and iii) on random bubble clusters, producing a progressive multidisciplinary synergetic effect.The proposed synergetic approach builds on the PI's preliminary research and employs novel experimental and numerical methodologies, some of which have been developed by the PI and his research group, to explore the physics of cavitation behaviour in interaction with bacteria and viruses.Understanding the fundamental physical background of cavitation in interaction with contaminants will have a ground-
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'NextPerception - Next generation smart perception sensors and distributed intelligence for proactive human monitoring in health, wellbeing, and automotive systems'.

assistant: **Objectives**

We put our lives increasingly in the hands of smart complex systems making decisions that directly affect our health and wellbeing. This is very evident in healthcare - where systems watch over your health - as well as in traffic - where autonomous driving solutions are gradually taking over control of the car. The accuracy and timeliness of the decisions depend on the systems’ ability to build a good understanding of both you and your environment, which relies on observations and the ability to reason on them.This project will bring perception sensing technologies like Radar, LiDAR and Time of Flight cameras to the next level, enhancing their features to allow for more accurate detection of human behaviour and physiological parameters. Besides more accurate automotive solutions ensuring driver vigilance and pedestrian and cyclist safety, this innovation will open up new opportunities in health and wellbeing to monitor elderly people at home or unobtrusively assess health state.To facilitate building the complex smart sensing systems envisioned and ensure their secure and reliable operation, the new Distributed Intelligence paradigm will be embraced, enhanced and supported by tools. It leverages the advantages of Edge and Cloud computing, building on the distributed computational resources increasingly available in sensors and edge components to distribute also the intelligence. The goal of this project is to develop next generation smart perception sensors and enhance the distributed intelligence paradigm to build versatile, secure, reliable, and proactive human monitoring solutions for the health, wellbeing, and automotive domains The project brings together major industrial players and research partners to address top challenges in health, wellbeing, and automotive d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Alcohol related cancers and genetic susceptibility in europe' to be submitted under Fifth Framework.

assistant: **Abstract**

Each year there are approximately 80,000 cases and 40,000 deaths of cancer of the upper aero-digestive tract (UADTI in the 15 European Union (EU) countries, making it the fourth most common cancer in the EU. The proposed study will recruit over 2500 cases of UADT cancers and a group of comparable controls in 9 centres of the EU. It will test specific hypotheses including genetic susceptibility to alcohol metabolisation, patterns of alcohol consumption and types of alcohol beverage, and dietary factors including low consumption of fruits and vegetables. Subsequently, it will investigate why some countries have incidence rates over 4 times greater than other countries. By incorporating information on genetic susceptibility, alcohol, dietary and other lifestyle patterns, the study will aim to identify individuals at a very high risk of developing UADT cancers.