RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Characterization and analysis of a family of uncoupling proteins. Importance for metabolic diseases' under Fourth Framework.

assistant: **Concept**

Research objectives and content - Study of the human Uncotll)lillg Protein-2 gene to determine the organisation of the gene, its possible polymorphism and its relationship with diseases related to the energy metabolism as diabetes, obesity, etc. - Analysis of the biological roles of the Uncoupling Protein-2 on the Resting Metabolic Rate, its relation to the effects in energy metabolism action of several hormones as thyroid hormones. - Study of the possible role of the Uncoupling Protein-2, which is also expressed in macrophages, spleen, thymus and lymphocytes, in the mechanism of inflamation immunity and the production of fever. -Search of other components of the family of Uncoupling Proteins, based on the cloning of a murine uncoupling protein mostly expressed in skeletal muscles Study of its capacity to uncouple respiration. Training content (objective, benefit and expected impact) This project will provide the applicant with background expertise to work with molecular biology techniques that constitute the basic step in the development of the work Several techniques involving gene cloning, sequencing, Southern, Northern and immmuno-blotting, plasmid construction and transient transfection of adypocite-derivated cell lines experiments, will be used as global approach to the study of gene organisation and function. The majority of these techlliqlles are in routine operation within the host institution (Centre de Recherche sur l'Endocrinologie Moleculaire et le Developpement), therefore the applicant should obtain definitive results within the postdoctoral stay. Links witll indllstry / industrial relevance (22) The relation of Uncoupling Protein-2 with the resting metabolic rate as well as the diet induced thermogenesis strongly suggests that it may be target for new ob
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Spectral and Optimization Techniques for Robust Recovery, Combinatorial Constructions, and Distributed Algorithms' in the context of a Horizon 2020 call.

assistant: **Objectives**

In a recovery problem, we are interested in recovering structure from data that contains a mix of combinatorial structure and random noise. In a robust recovery problem, the data may contain adversarial perturbations as well. A series of recent results in theoretical computer science has led to algorithms based on the convex optimization technique of Semidefinite Programming for several recovery problems motivated by unsupervised machine learning. Can those algorithms be made robust?    Sparsifiers are compressed representations of graphs that speed up certain algorithms. The recent proof of the Kadison-Singer conjecture by Marcus, Spielman and Srivastava (MSS) shows that certain kinds of sparsifiers exist, but the proof does not provide an explicit construction.    Dynamics and population protocols are simple models of distributed computing that were introduced to study sensor networks and other lightweight distributed systems, and have also been used to model naturally occurring networks. What can and cannot be computed in such models is largely open.    We propose an ambitious unifying approach to go beyond the state of the art in these three domains, and provide: robust recovery algorithms for the problems mentioned above; a new connection between sparsifiers and the Szemeredi Regularity Lemma and explicit constructions of the sparsifiers resulting from the MSS work; and an understanding of the ability of simple distributed algorithms to solve community detection problems and to deal with noise and faults.     The unification is provided by a common underpinning of spectral methods, random matrix theory, and convex optimization. Such tools are used in technically similar but conceptually very different ways in the three domains. By pursuing these goals together, we
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'INdustrial LEvitation Technology' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

About 40% of the electricity worldwide is consumed by rotating electrical machines. However most of the electrical machinesare not working at the optimum point from a process efficiency perspective. The electricity demand is growing andsimultaneously greenhouse gas emissions must be significantly cut every year according to global agreements and regionalterms of legislation. Cost-effective high efficiency motor development is highly required.SpinDrive provides highly efficient turn-key drivetrains (INLET), supported by frictionless magnetic bearings, for OriginalEquipment Manufacturers.INLET increases OEMs solutions’ system efficiency by at least 10%, reduce material consumption and simplify an equipmentinstallation process.INLET lowers the customer’s lifecycle costs by 35%.INLET reduces energy losses in the machine by half. For a 500-kW unit, this solution mitigates 200 tons of CO2 emissionsannually and enables 4-year payback time.INLET enables 20 years of maintenance-free operations and saves on average more than 500 000 EUR on the maintenancecosts during the product lifetime.INLET is completely oil-free, which allows OEM customers to enter rapidly growing markets and ensure an alignment with acontaminant-free environmental strategy.Compared with the other magnetic bearing providers, SpinDrive can design the entire drivetrain and make it more cost efficient.Our sensor and controller technology enable 70% lower cost level and competitive pricing of delivered products.SpinDrive is a spin-off of Lappeenranta University of Technology, Finland, founded in 2015. Our INLET innovation builds uponthe high-speed technology research at the university during the past 35 years. INLET has already reached TRL7 and a solidSMEI-1 feasibility study will guide our future growth as it wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Optical Manipulation of Colloidal Interfaces, Droplets and Crystallites'.

assistant: **Objectives**

This multidisciplinary research programme is focussed on the optical manipulation of interfaces, droplets and crystallites in colloidal model systems. In particular, we will use holographic optical tweezing and confocal microscopy to study interfacial phenomena in three different phase separated colloid-polymer mixtures, exhibiting colloidal liquid-gas, crystal-gas and nematic-isotropic phase coexistence, respectively. First, we will determine the full potential energy landscape of the optical traps using the relation between interface fluctuations and deformed liquid-gas interfaces. This will then be used to study the complex and anisotropic interfacial properties of crystal-gas and nematic-isotropic interfaces. In addition, we envisage quantitatively investigating the nucleation of colloidal liquid droplets, crystallites and liquid crystalline droplets in optical traps positioned at well-defined heights above the interface, which is a direct and quantitative measure for the undersaturation. This allows us to systematically study the relation between the quench depth, nucleus size and nucleation times. We will furthermore nucleate multiple droplets, crystallites and liquid crystalline droplets to study their optical trapping controlled coalescence and detachment, which will shed completely new light on for instance the single particle structure and dynamics upon coalescence and detachment. Finally, we will introduce large probe particles into the phase separated colloid-polymer mixtures, which enables the study of important phenomena such as heterogeneous nucleation and capillary condensation, crystallisation and nematisation. This ambitious project opens up a huge range of exciting possibilities to gain a deep and fundamental understanding of interfacial phenomena in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Human-Environment interactions in and around Venice Lagoon: micro-ecologies and geoarchaeological narratives from Roman Period to Middle Ages' (WaterScapes).

assistant: **Innovation**

WaterScapes is an interdisciplinary project that examines the relationship between environmental changes, natural constraints and potentialities and past societies settled in and around Venice Lagoon from the Roman to Medieval periods. WaterScapes has 3 core objectives. First, it will explore the high-resolution potential of paleo-archives, which have been undervalued by traditional archaeological research and text-based narratives. This will be achieved through geophysical surveys and coring missions in various sites (Venice, Torcello, Altinum, Lio Piccolo, Aquileia, Grado), laboratory research (geochemistry, bio-sedimentology, etc.) and contextual analysis of the settlements through literature reviews. Second, it will examine waterscapes as a human-made environment in Venice Lagoon in order to determine the historical roots and mechanisms responsible for the Holocene-Anthropocene transition. The research will be centred on multi-period waterscape archaeology to see how former cultures shaped themselves to the surrounding environments and developed different waterscapes through water management practices. WaterScapes will qualitatively and quantitatively analyse the degree and consequences of human interventions vs natural dynamics using multivariate statistical analysis based on bio-geoarchaeological proxies from the investigated sites. Third, WaterScapes will emphasise the social aspect of the materiality of the past, simultaneously measuring its legacy in the present. Establishing the relation between variations in past climatic conditions and coastal changes enables to contribute to the understanding and modelling of the ongoing processes, thereby providing tools for the policies of territory management. WaterScapes integrates perfectly in the principles of Europea
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Holistic approach to foster CIRCUlar and resilient transport InfrasTructures and support the deployment of Green and Innovation Public Procurement and innovative engineering practices' in the context of a Horizon Europe call.

assistant: **Objectives**

The overall objective of CIRCUIT is to develop a holistic approach supported by digital solutions and guidelines to foster the introduction of innovative engineering practices in the whole construction supply/value chain to foster The overall objective of CIRCUIT is to develop a holistic approach supported by digital solutions and guidelines to foster the introduction of innovative engineering practices in the whole construction supply/value chain enabling circular, sustainable resilient and smart transport infrastructure and a wider deployment of Green Public and Innovation Procurement. This will be achieved by:i.developing and deploying an innovative open-source digital platform (with advanced Circularity analytics and Supply/value chain matchmaking tools) interoperable with traditional engineering/design (BIM, Digital Twinm LCC, LCA) and traffic simulation tools; ii.introducing modular solutions, ecodesign and reusing concepts as alternative to traditional designs; iii.maximizing the use of biobased, Secondary Raw Materials (SRM) and Secondary Construction Elements (SCE) as alternative to traditional ones; iv.including in the decision making process of transport infrastructures design and route planning, information from updated traffic simulation tools to reduce incidents, accidents, congestion and future scenarios with autonomous vehicles). New elements and technologies for Circular, Smart, Resilient and Sustainable transport will be included in the design process to facilitate infrastructures upgrading and a quick adaptation to smart mobility and operations. CIRCUIT will also provide knowledge and technical solutions by exploiting the potential of four strategic pillars: Digitalisation, Recycle, Reuse and Energy. Different technologies will be validated in each of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Process for the reuse of fly ash derived from waste thermal treatments as substitution of critical and toxic flame retardants in the plastic manufacturing.' (COSMOS-Fenix) under Horizon 2020.

assistant: **Objectives**

COSMOS Fenix® (CF) is the trademark name of the patented process owned by Velaworks for the inerting of hazardous Air Pollution Control (APC) ashes derived from non-recyclable Waste Thermal Treatments, able to transform them into valuable secondary raw material (powder) that can be used as filler and flame retardant in plastic and rubber production. The easy and inexpensive process gives an effective answer to the huge problem of fly ashes landfill. At the same time, it offers to plastic and rubber manufacturers a very price competitive filler and flame retardant with very interesting flame resistant and strength properties, able to replace Antimony and Bromine in the plastics production process. The solution was validated at pilot scale at the waste thermal treatment plants of Brescia (Italy) and Bratislava (Slovakia), demonstrating the technical feasibility and the environmental safety of the process. The unique selling points are:•for Solid Waste Thermal Treatment operators  → 20% reduction of cost for the disposal of APC (130 vs. 160 €/ton) with a potential saving for the sector in Europe of  > 45M€/year;•for plastic manufacturers → flame retardants price equal to 380 €/ton, against the current market prices between 400 to 800 €/ton, with a saving up to 52%; no need of modifying the production process; safe and environmentally friendly material.Currently, about 2.4 million tons of APC ashes per year are treated in Europe, corresponding to a total Potential Market for CF of 1.200 M€/y, considering revenues from the treatment of the APCs and from sales of the secondary raw materials. The scope of Phase 1 is to demonstrate the technical/economical feasibility, achieving the following targets: i) Final Testing site for the pre-industrial plant installation (capacity = 4
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Probing the Geochemistry of the First Oceans with Novel ISOtope Proxies in Banded Iron Formations (BIFs): New Perspectives into Early Continental Weathering, Ocean Oxygenation and Mantle Geodynamics'.

assistant: **Innovation**

Since the beginning of Earth’s history, the oceans acted as an interface between the atmosphere, the continents, and the mantle via atmospheric exchange, weathering, sedimentation, and submarine volcanism. Such interactions make the composition of early seawater a unique recorder of the processes that have affected the Earth’s major reservoirs. Yet, this record has not been explored in details. Here, I propose to investigate the geochemistry of the first oceans that is recorded in Precambrian banded iron formations (BIFs) to address first-order questions related to the early evolution of our planet.The proposed project combines well-established radiogenic isotopic systems with novel and highly promising stable isotope tracers that will be developed as part of the project. These geochemical proxies will be measured on a unique collection of BIF samples deposited from ~3.8 to 0.7 Ga ago with the following objectives: (1) determine the origin, composition, and size of the first continents, (2) detect whiffs of oxygen in the early oceans in various depositional settings before and after the Great Oxidation Event (GOE), (3) identify the periods of intense hydrothermal activity through Earth’s history and link them to global mantle geodynamics. The proposed project will promote the application of state-of-the-art isotopic measurements, with an emphasis on further methodological development to set-up new isotope proxies. This innovative approach is needed to test previously suggested hypotheses, develop new ideas, and to tackle the challenging questions of the early Earth evolution from a different angle.


**Keywords:** Banded iron formations,  Early Earth,  Lu-Hf, Sm-Nd, La-Ce radiogenic isotopic compositions,  Ce and Eu stable isotopes,  Great Oxidation Event,  Archean cont
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Wood Nanotechnology for Multifunctional Structures' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Materials tend to be either structural or functional. Here focus is on biobased composites combining both aspects, using nanostructured wood templates. Wood is the most widely used biobased material for load-bearing structures, but the range of achievable properties and functions can still be increased. The objective is to develop scalable nanotechnology for wood structures, utilizing its nanocellulosic skeleton. Processing and materials design concepts are developed in the form of a wood nanotechnology toolbox. Focus is on transparent wood for engineering applications, a concept pioneered in my laboratory. Transparent wood can combine load-bearing properties with photonics functions and light weight.    The cellulose nanofibril skeleton in wood is a sophisticated reinforcement structure. For transparent wood, processing to nanoporous but mechanically robust templates without chromophores, is needed. Templates are then further functionalized using in-situ polymerization and/or inorganic nanoparticle precipitation. Molecular dynamics simulations are used to design polymers and methods for cellulose surface modification. Optical property research on material effects on scattering, polarization properties will then generate new ideas in ""wood photonics"". Device functions can be integrated in large structures, using anisotropy and the hierarchical structure in wood. Optically functional additives can be used to generate unique effects for applications such as lighting systems, LED panels, wood lasers, electrochromic windows or load-bearing and transparent panels with tailored combinations of transmittance and haze. Optical and mechanical properties are studied using experiments and modeling. The project team combines polymeric biocomposites competence with photonics exper
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Development of a novel blood-based diagnostic test for colorectal cancer'.

assistant: **Objectives**

A recent epidemiology of colorectal cancer (CRC) report demonstrated a significant CRC burden in European countries, which is still associated with very high mortality rates. The overall objective of the project is the development and commercialization of a test for the early detection of CRC based on the detection and measurement of cancer-specific autoantibodies present in blood of patients. The outlined test will detect simultaneously the presence in serum/plasma samples from CRC patients of specific autoantibodies (biomarkers) against a reduced number of tumor antigens (8-10). To reach this objective, several technological challenges have to be overcome, like to improve the sensitivity and detection limit in the early stages of CRC avoiding the obvious limitations provided by the invasive detection techniques extensively used, as the colonoscopy, and offering additional advantages compared to traditional CRC diagnostic methods, such the simplicity in applications, detection,  accuracy and a reduced cost. The assay for the detection of CRC will be established and validated with clinical samples and tested for their marketability, to finally overtake the regulatory process to obtain the CE marking. The results obtained in this project will have extensive impact and benefits for European population at risk, since early detection programs are essential to decrease mortality around 30-35% and drastically reduce the treatment costs of people affected by the pathology, assuring the sustainability of the European healthcare systems and others in the world. The main objective of this project is to obtain a colorectal cancer diagnostic kit clinically validated and regulatory approved as an in vitro diagnostic product (IVD), and as well, to penetrate in the CRC diagnostic mark