RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Pathogens and parasites in Mediterranean aquaculture' in the context of a Sixth Framework call.

assistant: **Objectives**

Research on pathogens and parasites in Mediterranean finfish aquaculture is less well advanced than in Atlantic waters. A shorter tradition of industrial aquaculture and usually weaker RTD structures in Mediterranean countries are factors probably accounting for this unbalance. Efforts to diversify Mediterranean aquaculture involve the use of new finfish species whose pathogens and parasites are still poorly known. In order to improve the knowledge of these organisms, this ToK Fellowship will develop a research programme on diagnosis and fish immune response to pathogens and parasites in Mediterranean finfish aquaculture.The objective of this ToK Fellowship is to improve the research capability of the host organization in two aspects: diagnosis and typing techniques of pathogens, particularly molecular-based, and techniques to evaluate the immune response to pathogens and parasites of finfish species of interests to Mediterranean aquaculture. The ToK Fellowship envisages a knowledge-acquisition phase where staff of the host organization will be trained at two partner organizations in diagnosis techniques, molecular typing and immunology for assessment of fish responses to pathogens and parasites. After this phase, the ToK Fellowship will develop a research programme at the host organization, where the knowledge acquired at the partner organizations will be adapted to Mediterranean finfish species.Research at the host organization will focus on developing molecular diagnosis techniques of emergent pathogens, optimising diagnosis protocols for designated pathogens and parasites, molecular typing of fish bacteria, and immunostimulation and assessment of immune responses of Mediterranean fish species against selected pathogens and parasites. The ToK Fellowship will endeavou
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The Syntax of the Mind: A Comparative Computational Approach' (SOMACCA), addressing dissemination and exploitation.

assistant: **Impact**

Does a shared computational basis underlie human artistic and linguistic accomplishments? Why do humans create and enjoy orderly patterns in music and visual arts? Are the mechanisms involved uniquely human or shared with other species? This project explores the cognitive underpinnings of language, music & visual art in humans, directly comparing them with the pattern perception abilities of other animals.  The proposal is grounded in a rigorous, mathematically-based theoretical framework (""formal language theory""), developed by computer scientists and theoretical linguists, which is extended here to include rule-governed patterns in the musical and visual domains.  The types of patterns recognizable by different species will be tested using innovative empirical testing methods (based on ""artificial grammar learning"") applicable to both humans and animals.  An important additional innovation of this research is the proposed use of repetitive visual patterns (akin to quilts, tilings and other ""decorative"" arts) and isomorphic musical and speech stimuli, all generated using the same ""grammars"" (abstract rule systems).  The addition of the visual dimension allows experimental manipulation of the short-term memory resources involved in pattern perception in a way impossible with acoustic stimuli.  The animal species tested include nonhuman primates and birds, and have been chosen to allow evaluation of the effects of relative brain size on pattern perception and cognition in general.  The doubly comparative approach adopted here will allow us to evaluate the degree to which general-purpose cognitive abilities, cutting across domains, differentiate human minds from those of other animals, or are shared.  Either way, the results of this research will have wide-reachin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Bioartificial organs and tissues: a euopean patnership in cellular engineering for improved health and industrial competitiveness' (1994-1998) under Fourth Framework.

assistant: **Objectives**

The aim of this proposed programme is to conduct a multi-disciplinary research activity in order to evolve bioartificial tissues and organs, utilising the phenomena and materials from cells. Specific objectives will focus on a study of cell-energy interactions and means for copying the in-vivo environment. Specific clinically related objectives are the investigation of: a vascular replacement; haemocompatible surfaces using cell membrane mimicry; methods to achieve neuronal guidance and interfacing; biologically derived cartilage repair material.The programme will commence by the establishment of core science and technology projects. Detailed plans and protocols will be agreed by all partners, and milestones confirmed. Cell types will be agreed, test rigs designed and constructed and methods for cell culture established. The mechanical influences imposed by cell interactions and by externally applied force fields will be studied, particularly with chondrocytes and vascular endothelial cells. The importance of the extra-cellular matrix is recognised, and the biochemical composition, as well as orientation of protein molecule chains will be investigated. Cell adhesion, motility and aggregation, and contact guidance, will be investigated in appropriate cell types. Test materials will be produced as a result of the above phase of research. This will then enable clinically related objectives to be addressed. We will develop means with which tubular structures can be produced from the co-culture of vascular endothelial cells and smooth muscle cells. The culture apparatus will allow varying shear stress to be applied, and we will determine the influences of shear stress on the characteristics of the developed structure. Using cell membrane mimicry we will develop and test phos
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Meninges: a new perivascular stem cells niche for widespread neurogenesis' (MENINGES-NET) targeting Seventh Framework.

assistant: **Abstract**

Adult neural stem cells (NSC) have been mainly described to be restricted within limited areas of the brain thought to be germinal remnants. However, new potential sites of NSCs activity have been recently described. The multiple locations of NSC niches, that increase in diseases, leaves open the question of whether and how these structures communicate throughout long distance. I and others have described a new player in the neurovascular unit: the perivascular meningeal stem cells. This cell population endow of neural differentiation potential and can migrate to the injured area contributing to brain parenchymal reaction following injury.With this IEF, I will have the great opportunity to join the Neurovascular link lab of Prof P. Carmeliet, Leuven, Belgium, to investigate the hypothesis that a subtype of perivascular cells may contribute to neuro-angiogenesis both in health and disease.I will address the following aims:(i) To genetically target perivascular meningeal stem cells. (ii) To understand the contribution of perivascular meningeal stem cells to neuro-angiogenesis in physiological and (iii) pathological conditions (stroke and cancer).I will follow the fate of perivascular meningeal stem cells by gene fate mapping them combining several techniques, including mouse transgenesis, stereotactic viral vector transduction and in vivo plasmid electroporation. Moreover, I will investigate possible molecular mechanisms of stem cell differentiation by targeting relevant metabolic pathways. Finally, I will use laser induced photoactivated stroke and genetically knock-in/-out cancers as diseases animal models. This multidisciplinary approach will eventually shed the light to identify new player in the complex events occurring in endogenous neural regeneration and cancer.Th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Performing a State: State-building in Iraq (2003-2006).'.

assistant: **Concept**

PS-IRAQ’s objectives: 1) study the relationship between knowledge production and political engineering in state and nation-building of occupied Iraq (2003-6); and 2) analyze how scientific knowledge of the state acted as a constituent element of political agency. This project also seeks to 3) develop detailed analysis of 2 sites of state and nation-building in Iraq (2003-6). The cases are the occupation’s and US efforts in: 1) restoring electrical supply and rebuilding the national electrical grid; and 2) the introduction of new Iraqi representative bodies. This project is interdisciplinary, drawing on comparative politics, the anthropology of state and economy, political geography, and social studies of science and technology. It examines how scholars from history, political science, political economy, anthropology and social theory have understood Iraq prior to and after the invasion, and how they engaged in the making and the transfer of ideas about the state. Data-collection relies on archival, library-based research, and interviews. The project generates conceptual and empirical insights relevant to European external action in Southern and Eastern Mediterranean Countries, especially crisis response and state-building. European excellence and innovation is promoted by developing a reflexive understanding of the relationship between social science knowledge and state-building practice and policy. Lessons from the US experience enhance the mutual understanding of US policy formation and social scientific knowledge formation processes. This will enhance potential for European international cooperation on state-building.


**Keywords:** state-building, Iraq, science and technology studies, electrification, democratization, expert knowledge, occupation, sectariansim, con
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Development of novel strategies for alkyl organoboron preparation via boryl radical reactivity' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Borylated molecules are some integral tools routinely used to aid molecular construction in both academia and industry. Their use in the Nobel Prize-winning Brown oxidation and Suzuki-Miyaura cross-coupling as well as Chan-Lam amination make them ubiquitous in organic synthesis. The invention of methods to form C–B bonds at sp3 carbons is of strategic importance to facilitate the preparation of saturated, hence 3D, molecules. As the pharmaceutical sector is aware of the greater clinical success of 3D molecules, developing methods able to prepare these materials is a topic of continuous scientific endeavour. Central to this quest is designing synthetic strategies able to deliver, in a divergent manner, building blocks that are stable and can be used in modular cross-coupling diversifications.This project seeks to substantially expand the fields of photoredox catalysis and boron chemistry by introducing a novel class of boryl radical precursors that will enable the generation and the use of these underdeveloped species in mainstream catalysis. This strategy will constitute a divergent platform for the generation of many novel 3D borylated molecules that will then be engaged in modular cross-coupling reactivity. Importantly, this project will provide access to materials that cannot be prepared by any other method.This research capitalizes on recent developments of the Leonori group that has experience in the generation and use of boryl radicals in synthesis.The completion of such an innovative and ambitious project at RWTH Aachen University will be facilitated by generating, transferring, sharing and disseminating knowledge, and will enhance my future career following the training plan envisioned.


**Keywords:** boryl radicals, cross-couplings, organoboron synthesis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'A Dual Approach to Many-Valued Semantics' (Adams) targeting Seventh Framework.

assistant: **Abstract**

Mathematical logic plays a crucial role in the 21st century society, indeed, in an era where information has become a key aspect of our lives, it provides a powerful mathematical framework for the study of the structure and the dynamics of information.  A particularly interesting aspect of mathematical logic is that it allows to take in account uncertainty, vagueness or subjectivity, yet in the rigorous setting proper to mathematics.Drawn from the applications, disciplines like many-valued logic, modal logic, reasoning under uncertainty, etc. have quickly developed a weaponry of sophisticated investigation tools that enabled the disclosure of a number of substantial facts about their expressiveness, functionality and scope. Nonetheless the investigations in these topics are far from being concluded, rather they are ready to be shifted to another level which could take into account inter-relations between those topics and offer an exchange of knowledge and methodology among their practitioners.This project fits into this tendency shift, proposing an investigation of new semantics for many-valued logic with tools traditionally developed in modal and intuitionistic logic. Indeed, while the algebraic approach has enabled a fine comprehension of many-valued logic, leading in few years to a very reasonable framework of study, the time is mature for seeking new interpretations and concrete representations of these logical systems.  As recent results put in evidence, the instruments developed in fifty years of studies on modal and intuitionistic logic, ranging from dualities to correspondence theory, are certainly the most qualified to help addressing this issues.The applicant has a strong background in many-valued logic and has already shown independency and vocation to resear
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Tackling the environmental concerns for deploying geothermal energy in Europe' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The advantages of using geothermal for power production and H&C are little known. Recently, deep geothermal energy production in some regions is confronted with a negative perception, and a special attention from some decision-makers, in terms of environmental performance, which could seriously hamper its market uptake. Media reports focus more on disadvantages than advantages. As a result, decision makers and potential investors have concerns about possible environmental impacts and risks involved in implementing geothermal projects, and social resistance often results in practical obstacles - such as significant slowdowns - to the deployment of the deep geothermal resources.  The first objective of the GEOENVI project is to make sure that deep geothermal energy can play its role in Europe’s future energy supply in a sustainable way. It aims to create a robust strategy to respond environmental concerns (by environmental concerns we mean both environmental impacts and risks): • by assessing the environmental impacts and risks of geothermal projects operational or in development in Europe, and  • by providing a robust framework to propose recommendations on environmental regulations to the decision-makers, an adapted methodology for assessing environment impact to the project developers, and finally   • by communicating properly on environmental concerns with the general public.  Secondly, GEOENVI aims at engaging with both decision-makers and geothermal market actors, to have the recommendations on regulations adopted and to see the LCA methodology implemented by geothermal stakeholders. The engagement with stakeholders includes to share knowledge by adopting an open and FAIR (findable, accessible, interoperable, reusable) data approach.


**Keywords:** geothermal, rene
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The development of scanning probe microscopy techniques for the study of genetic deletions' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Research objectives and content Scanning probe microscopy (SPM) is a family of microscopy techniques very promising in the study of biological applications. Atomic force microscopy can provide high resolution (<1 nm) topographic images of biological structures in air and liquid environment, preserving the native structure of the biological sample. Optical imaging has played a important role in biological investigations for a very long time. The near-field scanning optical (NSOM) can go beyond the diffraction-limited resolution of conventional optical microscopes to give optical images with resolution of about 20 nm. The objective of the project is the development of these SPM techniques and other recent SPM techniques such as tapping-mode phase contrast imaging or non-contact shear force microscopy (ShFM) to tackle an important problem in medicine of chromosome deletions. These chromosome losses (and gains) are of the fundamental importance in cancer and in birth defects. Although many of these chromosome abnormalities can be detected with conventional optical microscopy ; many cannot. SPM will allow not only the detection but also the pinpointing of the location of such sites. The different SPM techniques will be developed and combined to determine the banding pattern and the volume of the chromosomes. We will also expect to locate specific genes and high transcriptional bands. These studies provide the baseline ( for comparison of chromosomes with genetic deletions. The comparison will begin with mayor deletions and work towards microdeletions, not detectable by conventional cytogenetic methods. Finally, some attemp will be made to 'unwind' chromosome in-situ using a combination of chemical treatment and the AFM tip as a micromechanical tool in order to reveal further
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'ERA-NET: Aligning national/regional translational cancer research programmes and activities' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Cancer is a worldwide health burden and represents a major public health challenge in Europe. It is responsible for 25% of all deaths, being the second most common cause of death after cardio-vascular diseases and the main cause of mortality among people aged 45–64. Today, an estimated 9 million individuals in Europe live with cancer (Globocan 2008, http://globocan.iarc.fr/). Cancer became a chronic disease which contributed substantially to the growth of medical expenditures and constitutes a major socio-economic challenge for Europe as well as globally. A rapid and effective bidirectional transfer of relevant cancer research findings between bench and bedside would play a pivotal role in addressing top-priority needs at the EU level to reduce incidence and mortality of malignancies and to improve the quality of life of cancer patients.The proposed ERA-NET Cofund TRANSCAN-2, in continuity with the preceding and ongoing TRANSCAN ERA-NET, aims at linking translational cancer research funding programmes in 15 Member States, 3 Associated Countries, and a third country. By concentrating transnational resources, TRANSCAN-2 will provide a critical financial and scientific mass for tackling large-scale problems, relevant for improving translational cancer research globally.A co-funded joint transnational call (JTC) will be launched focusing on the topic “Intratumour heterogeneity in resistance to therapy and recurrence” followed by three additional JTCs that will be implemented in a frame of multinational translational cancer research programmes. In addition, strategies will be developed for the enlargement of the network, for improvement of coordination and for an efficient communication and dissemination of the results of the consortium as well as of the research projects fu