RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Integrated NetwOrks for seaMless And transparent service Discovery'.

assistant: **Concept**

The mission statement of NOMAD is the research, development and demonstration of middleware capable of seamlessly integrating available and future heterogeneous and homogenous network technologies (e.g. UMTS, Hiper-LAN2) as well as Internet compatible, multi-hop, ad-hoc networks into a single integrated network platform. Innovative technologies like mobility between devices and new algorithms for parallel usage of multiple access interfaces will be an essential part of NOMAD. Further, NOMAD will support transparent service discovery and provision over integrated networks by the means of an intelligent service location and configuration middleware mechanism. It will enable users to locate resources and services within their physical and network environment regardless of the underlying network technology. Important factors in this area will be the integration of user profiles and positioning systems information in the service discovery process.Objectives:Research, development and demonstration of middleware capable of seamlessly integrating available and future heterogeneous and homogenous network technologies (e.g. UMTS, Hiper-LAN2) as well as Internet compatible, multi-hop, ad-hoc networks into an integrated network platform. Research and develop highly innovative technologies like mobility between devices and new algorithms for parallel usage of multiple access interfaces and contribute to standardisation fora. Research and develop and demonstrate transparent service discovery and provision over integrated networks by the means of an intelligent service location and configuration middleware mechanism.Work description:1.User requirements, high level market assessment(WP1), focusing in the detailed study of end user and system stakeholders' requirements in light of the m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Advanced Research Initiatives for Nutrition & Aquaculture'.

assistant: **Innovation**

Sustainable development of European fish farming is dependent on the availability, environmental sustainability of feeds relying less and less on capture fisheries derived  fishmeal and fish oil. The European aquaculture industry has made a determined shift towards the use of feeds based on alternative ingredients which continue to ensure the health and welfare of fish and the nutritional value of farmed seafood. However, the long term effects of such interventions and over the full life cycle of the major species farmed in Europe need to be determined.To answer this challenge, ARRAINA will define and provide complete data on the quantitative nutrient requirements of the five major fish species and develop sustainable alternative aquaculture feeds tailored to the requirements of these species with reduced levels of fish meal and fish oil. By developing innovative vectors to deliver specific nutrients, ARRAINA will increase significantly the performance at all physiological stages thus improving overall efficiency of fish production.ARRAINA will apply targeted predictive tools to assess the long-term physiological and environmental consequences of these changes in the different species. This will provide flexibility in the use of various ingredients in the formulation of feeds which are cost-efficient, environmentally friendly and which ensure production of seafood of high nutritional value and quality.ARRAINA will design and deliver new pioneering training courses in fish nutrition to increase research capacities and expertise, particularly in countries of the enlarged EU.By developing applied tools and solutions of technological interest in collaborations with SMEs, ARRAINA will further strengthen the links between the scientific community and the EU feed industry and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The Rise and Fall of Textbook Science: Technoscientific and Pedagogical Expertise in the Making of Physics in Europe (1802-1902)' (1802-1902) targeting Seventh Framework.

assistant: **Abstract**

This project is a history of the making of physics as a discipline in Europe, built upon a multidisciplinary and cross-national analysis of the status of the physics textbook in education and research. The project spans the period between the pioneering establishment of secondary education in France (1802), and the simultaneous implementation of major educational reforms in France, Britain and Spain (1902), with repercussions lasting to the present day. Current knowledge suggests that textbooks had a major role in the establishment of science education, and the making of disciplines such as physics. However, their status and characteristics changed over time, in tune with dramatic changes in pedagogical and research practices. This project addresses this question through an approach which is innovative on four major grounds: a) Internationality, b) Interdisciplinary approach, c) Textbook and Pedagogy focus, d) Attention to the Material Culture of science and education. By means of six case-studies focused on the work of six major teachers and textbook authors, this project studies the production, distribution and use of physics textbooks and their changing status, through four combined aims: Mapping the pedagogical cultures of physics, and establishing the role of textbooks, the book trade and instrument making, respectively, in the making of physics as a discipline in Europe. Through synchronic and diachronic analysis, this project seeks to yield strong results in global perspective. Its objectives are to produce: 1) A new history of the emergence of physics in Europe based on an original approach and innovative focus. 2) A major contribution to the boost of the study of science pedagogy within history of science, history of education and book history, through the publ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'ENERGY HARVESTING IN CITIES WITH TRANSPARENT AND HIGHLY EFFICIENT WINDOW-INTEGRATED MULTI-JUNCTION SOLAR CELLS'.

assistant: **Objectives**

Transparent photovoltaics (TPV) possesses a huge untapped potential in the harvesting of solar energy where it readily can be embedded in buildings applications worldwide to significant reduce CO2 emissions, and support the needed development of nearly zero-energy buildings. TPV will increase the utilization of renewable energy directly where it is needed, and play a crucial role for the sustainable transformation of the energy sector in large cities. Using conventional photovoltaics, however, it is not possible to fabricate TPV elements without severe losses in efficiency and/or visual light transmittance. In the CITYSOLAR project, a new breakthrough concept for TPV will be developed by exploiting the combined use of emerging technologies, namely multi-junction solar modules developed from near-ultraviolet perovskite and near-infrared organic solar cells. Using advanced concepts within light management such as photonic crystals, nanophotonics and photon recycling and advanced module integration schemes, CITYSOLAR will radically change performance limits for TPV by significantly reducing losses related to light absorption and scale-up from individual solar cells to multi-junction modules. CITYSOLAR brings together world-leading European academic and industrial players, some with key intellectual property, together with two non-EU partners belonging to Mission Innovation countries specialized in the synthesis of advanced materials for hybrid and organic solar cells. The consortium will develop highly efficient and transparent solar cells and modules to increase the performance of available TPV technologies by 50%, and via innovative integration schemes present a route for its use in building integrated PV (BIPV) applications. This represents a strategic sector for Europe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Methods and software for evolutionary analysis of genome sequence data' to be submitted under Fourth Framework.

assistant: **Abstract**

Molecular evolutionary studies have traditionally concentrated on single genes or a single group of organisms. The advent of genome projects, and the rapid progress that has been made in sequencing the genomes of model organisms, has created a demand for changes in the way molecular evolutionary analysis is carried out. First, there is a pressing need for increasingly automated methods of analysis to cope with increased volumes of data (for example, assignment of proteins to super families and reconstruction of phylogenetic trees). Second, there is an opportunity to develop new methods of analysis that exploit the wealth of data on chromosome organization that has recently become available from genome projects (for example, the variation of base composition and gene density along chromosomes). We propose to address these issues by developing new analytical methods and writing new software to implement them. Specifically, we will develop methods for six areas of analysis described below. 1. Ribosomal RNA Database: Development of a database for storing, retrieving, and aligning large sets of homologous rRNA sequences. This database will serve as a model for specialised gene family databases. 2. Gene Family Alignment: Development of algorithms for adding new sequences to existing alignments, with special reference to ribosomal RNA. 3. Chromosome Organization and Compartmentalization: Analysis of gene composition, gene density, and gene orientation as a function of gene location, particularly with respect to chromosome landmarks such as replication origins, centromeres and telomeres. 4. Gene Duplication and Genome Rearrangement: Identification of duplicate genes and duplicate chromosomal regions; use of molecular clocks to estimate the ages of duplication events; methods fo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Molecular Analysis of Gene Regulatory Networks Underlying the Persistence of Drug Addiction' (2007-2013).

assistant: **Concept**

Drug addiction is a maladaptive form of experience-dependent plasticity that develops following chronic exposure to drugs of abuse. Drug experience induces plasticity of synaptic transmission within the neural circuitry of reward, which is thought to depend upon modulation of gene expression. Preliminary data I acquired demonstrates that chronic exposure to cocaine results in dramatic rewiring of gene regulatory networks within the nucleus accumbens, a key component of the brains’ reward circuitry and a central integrator of synaptic inputs implicated in the formation of addiction.Understanding the basis for this rewiring of gene regulatory networks, as well as identification and analysis of the neuronal population in which it is expressed, will be a major focus of work in my independent lab. These questions, and their implications for synaptic function and behavior, will be pursued in parallel at multiple levels, addressing the regulation of gene transcription both globally and in a cell-type specific fashion.The identity of transcriptional programs is defined by the repertoire of transcription regulators expressed in a cell. Preliminary data demonstrates elevated expression of Fos, FosB, CEBPB, KLF2 and ZFP36 in the nucleus accumbens of mice abstinent following chronic cocaine exposure, suggesting that these genes could underlie the rewiring of transcriptional complexes observed in abstinent mice. We will address the function of these genes by virus-mediated shRNA knockdown in the nucleus accumbens, as well as dissociated neuronal cultures. Comprehensive analysis of gene targets of CEBPB and KLF2 will be further pursued by chromatin immunoprecipitation followed by deep sequencing.This study is expected to result in identification of molecular mechanisms and specific g
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'A cost-effective and energy-efficient water treatment technology to remove pharmaceutical pollutants from urban wastewater' (DePharm).

assistant: **Innovation**

Widespread contamination from pharmaceuticals (synthetic or natural chemicals found in prescription medicines, over-the-counter therapeutic drugs & veterinary drugs) are finding their way into the drinking water supply, posing serious threats to public health. Pharmaceutical compounds such as hormones and endocrine disrupters are already responsible of major health problems, but modern wastewater treatment systems are not designed for effective removal of pharmaceuticals.Pharem Biotech brings to market the first enzyme-carrying filtration system able to remove a large range of organic pollutants (pharmaceuticals and other biological active compounds such as Bisphenol A, PFOS, antibiotics, hormone disruptors, etc.) in wastewater treatment plants, without additional energy requirement. By combining the enzymes with biotechnological techniques and a process for applying the enzymes onto a physical filter, the solution provides a wastewater treatment process step that can be added onto the existing water treatment processes at sewage treatment plants and work without external energy. The solution is based on modified enzymes which are 200 times more effective than native enzymes, resistant to low temperature, resistant to low pH and with high levels of stability and activity.  The solution was successfully demonstrated in an industrial environment (Hammarby Sjöstadsverk in Stockholm, Sweden, a test and demonstration facility for innovative waste water purification run by the Swedish Environmental Institute) where it effectively removed the pharmaceutical and other organic pollutants from urban wastewater at a price that is 10X lower than alternative solutions. Pharem aims to equip 50 WWTPs by 2020, for a turnover of €30M+.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Chemical compounds targeting MERCs: identification of their partners in physiological and pathological conditions'.

assistant: **Objectives**

Mitochondria and Endoplasmic Reticulum (ER) Contact sites (MERCs) are points in which the surfaces of the two organelles run in parallel. MERCs gained attention recently due to their fundamental contribution to several cell processes, such as Ca2+ and lipid homeostasis, mitochondrial fission, and apoptosis. To execute and regulate these processes, MERCs must be dynamic and react to the needs and metabolic state of the cell. Interestingly, the organelles stay separated by a narrow cleft, usually 10-50 nm apart. The width of the MERCs gap and its size (i.e. area of a membrane involved in the contacts) are the critical parameters that determine their cellular functions. Despite the literature on MERCs has grown considerably, the precise molecular structure and role of MERCs are poorly defined.In the proposed project I will investigate the regulation of MERCs plasticity by small molecule compounds. Using a high-content phenotypic screening approach, based on a FRET mitochondria-ER proximity probe, I will identify the compounds affecting MERCs structure. These bioactive hits will be validated through biochemical, confocal and electron microscopy assays. Moreover, I will search for the protein target of the hit molecule using the methodology developed during my PhD. Finally, I will evaluate the capability of the identified hit molecules to act as therapeutic lead compounds for pathological conditions by testing the identified molecules on cells with defective MERCs. Therefore, this project will open new research paths related to both MERCs structure and function.I will obtain deep knowledge of mitochondrial biology and high content screening, which will complement my current expertise obtained during PhD. Besides, I will develop transferable skills needed to successfully acco
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Informational properties of networks under communication constraints' (InfoNet) targeting Horizon 2020.

assistant: **Abstract**

Motivated by applications to information networks such as wireless and ad-hoc, this research will explorefundamental informational properties of networks under communication constraints. In the standardapproach, the network is assumed to be fully connected and/or the information it carries is treated as acommodity. Here, we will investigate a markedly different paradigm where limitations on the nodes’connectivity in the network are imposed and pieces of information can be combined. Examples includestorage systems in which the links are established by physical proximity or system architecture, as well aslow-power wide-area networks for Internet-of-Things applications. We will consider a broad spectrum ofmodels and topics ranging from efficient information encoding and network resiliency to information lossunder corrupt nodes to cooperative models and network information accessibility. We will study these topicsunder specific network families and random networks.While prominently theoretic, the proposed investigation is expected to yield insights and design rules for theconstruction of information networks, e.g., via new data placement techniques and communication protocols.Moreover, we plan to devote part of our study to practical aspects by implementing and testing the theorydeveloped in real-world networks. Such developments may well lead to a paradigm shift in the design ofresource-limited wireless communication systems, and potentially reduce energy consumption, delays, andincrease the overall information reliability. Lastly, our motivation stems from the perception that naturallyoccurring phenomena in general networks are dependent on the information carried by them; this perceptionis what drives both the research questions we pose and the mathematical model we defi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'High Performance Computing Technologies for Smart Distribution Network Operation' (HiPerDNO), addressing dissemination and exploitation.

assistant: **Impact**

Future electricity distribution networks with mass deployment of network equipment sensors and instrumentation, millions of smart meters, small-scale embedded generation, and responsive load will generate vast amounts of data requiring near to real-time analysis. So-called cloud and grid computing will enable scalable data mining, feature extraction, and near to real-time state estimation. These and other HPC tools and techniques have been recently developed to cost-effectively solve large scale computational challenges in areas such as genomics, biomedicine, particle physics and other major scientific and engineering fields that require similarly scalable communications, computation and data analysis. Based on such recent success it is the aim of this proposal to develop a new generation of distribution network management systems that exploit novel near to real-time HPC solutions with inherent security and intelligent communications for smart distribution network operation and management. Cost effective scalable HPC solutions will be developed and initially demonstrated for realistic distribution network data traffic and management scenarios via off-line field trials involving several distribution network owners and operators.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Identification and characterization of tumor antigens and development of diagnostic tools for cancer.' (1998-2002), addressing dissemination and exploitation.

assistant: **Impact**

Abstract: Identification of specific-specific antigens has become a promising tool for the diagnosis and the control of cancer treatment. Specific-specific antigens are used as surrogate markers that allow for customized patient care. However, candidate antigens are rare, usually unspecific, and techniques for their identification are cumbersome and labour-intensive. Delphi offers a unique and highly powerful approach to screen for new specific-specific antigens. The Delphi technology employs cDNA libraries generated from human specific cells followed by antibody-mediated screening for specific-specific antigens using the antilogous serum from human patients. This technology avoids all drawbacks of previously described screening methods and allows to rapidly isolating antigens specifically associated with tumours.