RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Clinical development of a Pfs48/45-based malaria transmission blocking vaccine' (REDMAL) under Seventh Framework.

assistant: **Objectives**

Malaria vaccines are needed to reduce the unacceptably high burden of disease and death in particular in the lowest income countries. Malaria vaccines aim at interruption of the life cycle of the parasite Plasmodium falciparum by induced immune responses in the humans. Transmission-blocking vaccines (TBMV) specifically aim at an arrest sexual stage development preventing the generation of infectious mosquitoes. TBMVs are the most effective tools for reduction of the spread of malaria in the population. This is indispensible for sustained control, elimination and eventually eradication. Pfs48/45 is the most advanced EU-developed malaria TBMV candidate. PF10C is a subunit of Pfs48/45 that has been produced as R0-PF10C in a 20L fermentor.  Immunization with 100% properly folded R0-PF10C induced transmission-blocking activity in 100% of immunized mice.Objectives: 1) Manufacture R0-PF10C at cGMP grade and 2) Prepare for clinical trials with R0-PF10C in Africa.Workplan: R0-PF10C production will be optimized and up-scaled for release of clinical grade batches for human trials. To prepare for clinical testing to Africa, preparation for Phase II will be initiated. A Phase II trial of a malaria TB vaccine will require a specific design. Important transmission parameters will be collected and introduced in a mathematical model to study the possible impact on transmission in the selected study area.Milestones: 1)  Batch release R0-PF10C for use in clinical trial; 2) Preparation of field site for phase IIb clinical trial with R0-PF10C vaccine
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Computer aided design of the calibration process in profile extrusion' (1994-1998) under Fourth Framework.

assistant: **Objectives**

The design of calibrators - the cooled metal blocks that solidify and fix the cross-section of complex extrusions such as PVC window and door profiles, rubber sealing strips, etc. - is difficult, besause it must take into account cooLing rates, shrinkage and thermal stress development. The objective is to provide a computer aid for callibrator design by: 1. Setting up a detailed mathematical model of calibration. 2. Implementing this using finite element methods. 3. Carrying out material characterisation, and experimental trials to assist with model development and validation, at the premises of the collaborating Company.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Genetic engineering as an approach to enhance the lipid-binding properties of the Flowering locus T, the member of the Phosphatidylethanolamine-binding protein family' to be submitted under Horizon Europe.

assistant: **Abstract**

EU Mission for Adaptation to Climate Change perceives the improved dryland agriculture as one of the ways to adapt and survive. Humans have the technology and processes to address the major agricultural issues today, such as pest infestation, droughts, the misuse of herbicides; however, the global warming requires a new set of tools and the willingness to adapt from all of us. The key developmental switch for the flower/fruit bearing plants is the change from vegetative to reproductive growth, and the timing is crucial. The climate changes have been already impacting the flowering, as several perennial and annual crops have flowered earlier by about 2 days per decade, during the last 50 years. The flowering locus T is a plant protein highly recognized as a part of the florigen complex, a mobile protein that is produced in the leaf companion cells and transported to the plant shoot apex to induce flowering. My previous work was focused on the FT preference to bind to phosphatidylglycerol (PG), over other lipid species, in the temperature-dependent manner, and the impact on the flowering time. The MSCA Project will address the relevance of the wider array of FT-PG interactions, by utilizing the genetic modifications to produce and characterize the FT mutant proteins with enhanced lipid-binding properties. The super sticky FT would be difficult to remove from the membrane, which could have a potential industrial application. A challenge would be to create the protein that could not bind to the membrane, which will shed a new light onto flowering regulation. The multidisciplinary approach, consisting of molecular biology, biochemistry, structural chemistry, and biophysics, will produce deliverables for the subsequent in planta project. The measured impact of different ambie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'HArmonization for the secuRity of the web technologies and aPplications' to be submitted under Fifth Framework.

assistant: **Abstract**

Internet is a completely open network putting all security components (confidentiality, authenticity, integrity, availability) at risk. The evolution and rapid change of the Web technologies bring uncertainty and confusion. The security issue should be resolved before applications over the Web can be realised. The objectives of this project (development and demonstration of tools for the harmonisation of applied and emerging Web oriented security systems in telemedicine) is a challenging task that can only be achieved within the framework of an international and targeted co-ordination. Links with health authorities and all relevant standardisation bodies will be achieved in order to contribute valuable impact in order to solve the security problem over the Web focused in the telemedicine sector. The literature, the wealth of existing results, findings and actual testing will provide guidance to HARP.Objectives:The overall objective of this project is to develop technologies and tools for the integration of Web oriented security systems and combine coherent services to demonstrate and quantify the value of security tools/mechanisms/systems harmonisation in business and citizen needs in the Information Society.This overall objective is broken down into the following sub-objectives:a) Review/analyse Web components used in the telemedicine sector in terms of security,b) Investigate the impact of TTPs in the secrrity of Web-based telemedicine applications.c) Develop harmonising software and tools to cope with the diversity of the Web components,d) Design, integrate, validate a harmonising, cost-effective, user-friendly security platform based on TTPs for securing integrated telemedicine applications,e) Demonstrate HARP's integrated security solution in the telemedicine secto
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Evolutionary Computation for Dynamic Constrained Optimization Problems' to be submitted under Horizon 2020.

assistant: **Abstract**

Evolutionary computation (EC), as an efficient tool, has been widely applied to solve different kinds of stationary optimization problems. However, many real-world optimization problems are dynamic constrained optimization problems (DCOPs), where the objective function, constraints, decision variables, and environmental parameters may change over time. At present, very few attempts have been made to investigate this kind of optimization problems in the communities of optimization and EC. This project aims to fill this gap. In this project, we will concentrate on the design, analysis, and applications of EC for DCOPs, including the following five main aspects. Firstly, we will design a set of benchmark dynamic constrained optimization test environments which can resemble real-world scenarios. Secondly, we intend to design standardized performance indicators to evaluate EC methods for DCOPs. Thirdly, based on the standardized dynamic test and evaluation environments, we will design some novel and effective EC methods to solve DCOPs. Fourthly, we will present theoretical analysis of EC with different constraint-handling techniques for DCOPs, with the aim of establishing the theoretical foundation of this area. Finally, applying the developed EC methods to deal with DCOPs in rail networks is also one key aspect of this project. This project has great potentials to fundamentally change the way in which DCOPs are treated, both from a real-world point of view and from the point of view of advancing our theoretical understanding. The research results of this project will be of great interest to academia in many fields and of significant benefit to many industries that involve DCOPs.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Innovative methodology in quality assessment of coatings (MANIAC)' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

A robust methodology for determination of quality and long-term performance coatings will be developed, by using new accelerated weathering techniques and by looking at the role of some important additives. The developed methodology will lead to shorter time-to-market for new environmentally friendly coatings, reducing health and safety risks connected with the use of solvents and other chemicals commonly used today. It will ensure high durability and good performance and speed up development of new coatings and additives. The innovative aspect lies in the application of knowledge of degradation processes, and the use of advanced analytical techniques to simultaneously deal with the problems of the complex nature of coating systems and the complexity of weathering conditions, and their effects on changes in terms of chemical and physical properties.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Noise and vibration in eco-efficient powertrains' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

With increasing regulatory pressures to reduce emissions, road transport has to play its part. Over the next 30 years, as we shift towards EVs, downsized IC engines and hybrids with eco-powertrains will be central to the automotive sector. ECO DRIVE will develop new technologies for the testing and simulation of eco-powertrains, addressing the complex challenges related to combustion noise, the irritating sound from electric motors, transmission-induced NVH (Noise, Vibration and Harshness) and driveline torsional vibrations, leading to new designs with improved eco-efficiency and NVH performance. The project offers a multi-disciplinary research-training program to the ESRs, with the ultimate aim being to create a new generation of NVH professionals for the transport sector. The technical-scientific challenges are tough: to investigate highly innovative simulation, testing and signal-processing methods for advanced NVH analysis and the engineering of downsized IC engines, e-motors, and novel lightweight transmission systems, to validate and demonstrate the applicability of the developed approaches in an industry context, on both powertrain tests rigs and new vehicles. ECO DRIVE has 9 Beneficiaries from leading academic institutions, top research centres and Europe’s premier vehicle producers. Together, they address the triple-I dimension of research training, being International, Interdisciplinary and Intersectoral. The ESRs profit from top scientific research guidance in combination with highly relevant industrial supervision through the secondment exchanges between the research organizations and the industry partners. The training programme is designed to cover not only eco-powertrains, but also critical transferable skills. The participating organisations gain from th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Astrophysics Center for Multimessenger studies in Europe' (ACME).

assistant: **Concept**

ACME (the Astrophysics Centre for Multi-messenger studies in Europe) addresses the EC Call to provide wider, simplified, and more efficient access to the best research infrastructures (RI) available to researchers in the astronomy and astroparticle physics communities. ACME is set up to realize an ambitious coordinated European-wide optimization of the accessibility and cohesion between multiple leading RI, offering access to instruments, data and expertise, focused on the new science of multi-messenger astrophysics. ACME will forge a basis for strengthened long-term collaboration between these RI irrespective of location. Collaboration and user training will be specifically aimed at levelling up access opportunities across Europe and beyond.ACME objectives are:- implement the European roadmaps’ recommendations and act as a pathfinder to broaden, improve and align access to the respective RI services and data, and assess and evaluate new models for better coordination and provision of at-scale services- provide harmonized and inclusive trans-national and virtual access to world-class RI- develop centres of expertise providing expert support to enable easier access for more researchers- improve science data products management to facilitate both focused research goals and serendipitous discoveries, implementing FAIR approaches to broaden access- improve interoperable systems for rapid identification of astrophysical candidate events, and alert distribution to the network of RI and scientific consortia to optimize follow-up observations- provide training for a new and broader generation of scientists and engineers- open the astrophysics and astroparticle physics data sets to other disciplines, such as environmental studies or marine biology for the undersea neutrino facil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Climatic and anthropogenic drivers in the Holocene vegetation development of two large European river basins: the Maritsa Valley in Bulgaria and NW Turkey and the Tisza Valley in E Hungary' (HBTPOLARCH) targeting Sixth Framework.

assistant: **Abstract**

While the Marisa River Basin in SE Bulgaria and NW Turkey, and the Tessa Lowland in E Hungary are key areas in respect of the spread of farming in Europe, their environmental history and the human impacts on their landscapes remain unknown. In 2002, four sediment cores with well-preserved pollen and plant macrofossils were recovered from lakes in these areas all in close proximity to key archaeological sites. The prime objective of this research is to investigate the palate-environmental record of Late Glacial and Holocene landscape transformations brought about by agriculture and pastorals using a multi-disciplinary approach, in which a wide-range Quaternary ecological-ecological techniques (pollen-, plant macrofossil-, micro charcoal analyses, AMS radiocarbon and techno-chronological dating) are combined with archaeology. The principal hypothesis to be tested states that despite the existence of long-lived settlements and a large quantity of domesticated plants and animals there was little human impact by farmers in SE Europe until the Bronze Age. Most of the pollen sites on the bases of which this hypothesis was formulated are however located at relatively large distance from key early farming sites. Our sites, in contrast, lie next to well-documented prehistoric settlements; accordingly the scale at which early farming was practiced can be dependably resolved. The second aim is to define and explain regional changes in climate-climate, particularly in water-balance at centennial to millennial scale. An important research question is whether the pollen records from the Bulgarian and Turkish sites show a contrasting Early Holocene cooling and increased humidity characteristic for the Eastern Mediterranean pollen-based palaeocliamte reconstructions but not detectable i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Global Terrorism and Collective Moral Responsibility: Redesigning Military, Police and Intelligence Institutions in Liberal Democracies' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

International terrorism, e.g. Al Qaeda, IS, is a major global security threat. Counter-terrorism is a morally complex enterprise involving police, military, intelligence agencies and non-security agencies. Counter-terrorism should be framed as a collective moral responsibility of governments, security institutions and citizens. (1) How is international terrorism to be defined? (2) What is the required theoretical notion of collective moral responsibility? (3) What counter-terrorist strategies and tactics are effective, morally permissible and consistent with liberal democracy? Tactics: targeted killing, drone warfare, preventative detention, and bulk metadata collection (e.g. by NSA); (4) How is this inchoate collective moral responsibility to be institutionally embedded in security agencies? (i) How are security institutions to be redesigned to enable them to realise and coordinate their counter-terrorism strategies without over-reaching their various core institutional purposes which have hitherto been disparate, (e.g. law enforcement versus military combat), and without compromising human rights, (e.g. right to life of innocent civilians, right to freedom, right to privacy), including by means of morally unacceptable counter-terrorism tactics? (ii) How are these tactics to be integrated with a broad-based counter-terrorism strategy which has such measures as anti-radicalisation and state-to-state engagement to address key sources of terrorism, such as the dissemination of extremist religious ideology (e.g. militant Wahhabi ideology emanating from Saudi Arabia) and the legitimate grievances of some terrorist groups (e.g. Palestinian state)? What ought a morally permissible and efficacious (i) structure of counter-terrorist institutional arrangements, and (ii) set of c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Empowering Community-Led Action in the Atlantic & Arctic' (BlueActionAA) under Horizon Europe.

assistant: **Objectives**

Empowering Community Led Action in the Atlantic & Arctic (ACT-AA) aims to mobilise and engage communities across the Atlantic and Arctic regions in ambitious efforts to restore and protect marine and freshwater ecosystems. By fostering community-led initiatives, the project seeks to make significant progress toward the objectives of the EU Mission “Restore our Ocean and Waters by 2030.” ACT-AA will provide comprehensive support to local stakeholders, including financial aid through cascading grants, technical assistance, and capacity-building resources to ensure effective and sustainable ecosystem restoration actions.ACT-AA’s key components include:1. Cascading Grants for Community-Led Pilot Actions: Awarding at least 5 grants ranging from EUR 200,000 to EUR 2 million each to innovative projects addressing local ecological and socio-economic challenges.2. Support for Transition Agendas: Funding at least 20 strategic roadmaps, each up to EUR 100,000, to guide communities in achieving the Mission’s objectives and ensuring long-term sustainability.3. Technical Assistance: Providing tailored support, including business plan development, impact assessments, and capacity-building programs, to enhance local stakeholders’ ability to implement and scale innovative solutions.Expected outcomes include:1. Demonstrable, measurable progress towards the Mission’s objectives through well-managed, community-led actions.2. Support for EU member states and stakeholders in implementing marine and freshwater ecosystem relatedlegislation.3. Increased engagement and resource mobilization from communities to restore oceans, seas, and waters.4. Enhanced readiness at the local level to deploy innovative restoration solutions.ACT-AA will ensure broad participation, leveraging local knowledge and