RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Calcareous dinoflagellate culturing experiments: understanding the life cycle of oceanic species'.

assistant: **Innovation**

Din flagellates are primarily unicellular aquatic organisms that typically occur as biflagellate motile cells. At ascertain stage of their life cycle, several marine din flagellates produce non-motile cells surrounded by calcareous wall. Calcareous din flagellates constitute an important group of the marine calcareous phytoplankton and their cysts are subject to an increasing number of palaeoenvironmental studies. However, fundamental biological and ecological characteristics of these organisms are yet unknown.Neritic and oceanic habitats are characterised by different species. Neurotic species produce calcareous resting cysts, within the sexual reproduction cycle. In cultures, the motile stage is the dominant phase and resting cystproduction occurs only when the conditions for vegetative growth are unfavourable. By contrast, in the most abundant oceanic species (Thoracosphaera hemi) the calcareous stage is dominant and is formed during the vegetative cycle. Apart from T. hemi, approximately 10 other extant oceanic species exist. There are strong indications that these species also calcify in their vegetative stage, as they show a constant production of calcareous non-motile cells that make up more than 50 % of all specimens within a culture under normalconditions.DINO-CULT will test the hypothesis of a shift in the life cycle of oceanic calcareous din flagellates, through which the calcareous stage became dominant. Policy investigations on motile and non-motile stages of cultures will reveal when in the life cycle calcareous tests are produced. The effect of environmental parameters (e.g. light, temperature, nutrients) on cyst production will be investigated in experiments under controlled laboratory conditions and the results will be applied in a palaeoenvironmental c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Cellular Structures for Impact Performance' (CELPACT).

assistant: **Concept**

The European aircraft industry has strong interest in novel structural concepts for future aircraft fuselage and wing structures with lower fabrication costs and high performance. An important class of these next generation aerospace materials will employ advanced manufacturing techniques for sandwich structures with cellular core materials giving high strength/weight and improved impact resistance under critical aircraft load cases such as foreign object impact from birds, tyre rubber and runway debris. The main objective of the project is development and design of cellular materials and twin skinned sandwich structures made from hybrid composites and metals. CELPACT will progress fabrication technology for cellular metals based on selective laser melting and develop new fabrication concepts for hybrid composite sandwich structures with folded cellular composite cores. Computational methods will be developed based on micromechanics cell models with multiscale modelling techniques for understanding progressive damage and collapse mechanisms and used for structural analysis. Impact performance is critical for sandwich aircraft structures and the simulation tools will be used to design efficient impact resistant aircraft structures. Structural integrity of these advanced cellular structures will be assessed by testing generic cellular beam and shell structures under high velocity impact conditions relevant to aircraft structures. CELPACT is an upstream research project concerned with development of breakthrough technologies and design tools for future airframe structures with high efficiency and safety. It has been prioritised by the European Aeronautical Scientific Network EASN. The consortium from five European countries contains seven leading universities with research
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Design Support and Tooling for Embedded Control Software' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The efficient design of embedded systems is hampered by the separation of engineering disciplines in current state of the art development approaches. A methodology to address system-level design issues across discipline boundaries is lacking and tool support is poor. This design gap" inhibits iterative and concurrent engineering, leading to sub-optimal designs and long development lead times. Moreover, the design gap is widening because of increasing system complexity and increasing capabilities of the system artifacts used.<br/>DESTECS will create a methodology and supporting open tools platform for the collaborative and multidisciplinary development of dependable embedded real-time control systems. We will develop a methodology combining continuous time and formal discrete event modeling with support for iterative design evolution.<br/>Model analysis will be based on co-simulation and the framework will support explicit modeling of faults and fault-tolerance mechanisms from the outset. Tool support is crucial: the methodology will be supported by an open, extendible tools platform, populated with plug-ins supporting co-simulation, test and code generation. DESTECS does not replace current industry practice but it will facilitate and support the cross-discipline design dialogue by integration of domain-specific best practices. The methods and tools development is driven by industry-led case studies which also provide evaluation of the emerging technology.<br/>The novel aspects of this proposal are the use of a systems-level modeling approach based on co-simulation of formal models, the explicit modeling of faults and fault-tolerance at this level and the support for lightweight trade-off analysis between design alternatives on the basis of extra-functional properties,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Active Wind Farms: Optimization and Control of Atmospheric Energy Extraction in Gigawatt Wind Farms'.

assistant: **Concept**

With the recognition that wind energy will become an important contributor to the world’s energy portfolio, several wind farms with a capacity of over 1 gigawatt are in planning phase. In the past, engineering of wind farms focused on a bottom-up approach, in which atmospheric wind availability was considered to be fixed by climate and weather. However, farms of gigawatt size slow down the Atmospheric Boundary Layer (ABL) as a whole, reducing the availability of wind at turbine hub height. In Denmark’s large off-shore farms, this leads to underperformance of turbines which can reach levels of 40%–50% compared to the same turbine in a lone-standing case. For large wind farms, the vertical structure and turbulence physics of the flow in the ABL become crucial ingredients in their design and operation. This introduces a new set of scientific challenges related to the design and control of large wind farms. The major ambition of the present research proposal is to employ optimal control techniques to control the interaction between large wind farms and the ABL, and optimize overall farm-power extraction. Individual turbines are used as flow actuators by dynamically pitching their blades using time scales ranging between 10 to 500 seconds. The application of such control efforts on the atmospheric boundary layer has never been attempted before, and introduces flow control on a physical scale which is currently unprecedented. The PI possesses a unique combination of expertise and tools enabling these developments: efficient parallel large-eddy simulations of wind farms, multi-scale turbine modeling, and gradient-based optimization in large optimization-parameter spaces using adjoint formulations. To ensure a maximum impact on the wind-engineering field, the project aims at op
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Genome Stability Mechanisms in Aging'.

assistant: **Innovation**

Genome Instability has been recognized as causal factor of cancer and recently also as a major contributing factor of aging. A number of progeroid (premature aging-like) syndromes are linked to defects in nucleotide excision repair (NER). NER thus provides a highly relevant experimental system to study the role of genome stability in aging. Using the NER system we recently uncovered a novel link between DNA damage accumulation and the regulation of longevity assurance programs. We propose to use the powerful genetic system of C. elegans to identify mechanisms through which the stochastic accumulation of damage impacts aging and genetic pathways of longevity regulation. We will pursue three complementary experimental strategies: (1) genetic identification of novel response pathways to persistent DNA damage, (2) investigation of DNA damage resistance mechanisms that promote longevity, and (3) a targeted candidate approach to uncover the underlying mechanisms that ensure genome integrity in lifespan extension. This proposal aims at the discovery of novel genes functioning in genome stability and longevity regulation that might be instrumental for the development of preventive therapeutic strategies for age-related pathologies as well as for the treatment of rare genetic progeroid disorders.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Copying As Common Practice in Early Modern Architecture' to be submitted under Horizon Europe.

assistant: **Abstract**

This project advances the hypothesis that techniques of mechanical drawing, and specifically, drawings produced by manual copying and direct tracing, served as the bedrock of early modern architectural education prior to the advent of formal schools of architecture. The normative histories of fifteenth- and sixteenth-century Italian architecture have relegated drawings of mechanical subject matter (construction machinery, scaffolding systems, structural diagrams, military devices) to a lower, non-artistic status. These drawings are deemed inferior not only due to their subject matter, but also due to their ubiquity; the mechanical drawings used by early modern architects were widely circulated and routinely copied. Indeed, copying drawings and traces have long been considered corrupt. In the foundational discussions of disegno (the practice and product of drawing), Giorgio Vasari explicitly ridiculed copying practices, and the “infinite” number of substandard artists who employ techniques of tracing. In turn, he celebrated drawings that were demonstratively autograph or individual as the embodiment of their creator’s singular “genius.” This framework lay the foundation for modern history’s critical assessment of drawings and cemented the idealization of early modern Italy’s “great” architects. While recent decades have seen a notable increase in research on techniques of copying and tracing in the study of early modern painting, there remains a critical absence of scholarship that examines the derivative practices that underscored early modern architecture. Looking beyond anachronistic conceptions of “art,” “architecture,” and “engineering” and examining a broader corpus of early modern architectural drawings. Identifying images that are formally and technically related
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Opet Chp/dh cluster' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

Extended use of CHP-production and DH targeting energy efficiency, environmental protection and fuel flexibility are central EU objectives. The aim is a systematic effort for the further use and market uptake of the different CHP/DH technologies in favour of EU policies. The OPET network will serve as facilitator.The cluster addresses a number of objectives, which are of key importance for the development of the CHP/DH sector:a) Meeting the challenge of modernisation of the DH-systems in CEEC, and improving the sector's economic and environmental performance,b) Stimulation of the market development and elimination of barriers for the utilisation of new/innovative CHP technologies, eg. small, mini and micro scale CHP technologies,c) Facilitating the further introduction of biomass in CEE andd) Informative measures aiming to facilitate EU's CHP directive as well as the transfer of state-of-art knowledge
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Circuit and cellular mechanisms for computing spatial vectors to shelter during escape' (EscapeVector).

assistant: **Innovation**

Executing actions that move the body across space to reach goals is a task that animals constantly perform. In some cases, the goal is within direct reach of sensory systems, but in others the goal location has to be retrieved from memory and requires moving towards to a memorised point in space. Previous work has identified neural circuits that represent space, and devised models for transforming object-centred spatial representations into body-centred coordinates, but we do not know the mechanisms by which actions are computed to reach memorised locations. Our goal is to uncover these mechanisms, by investigating instinctive escape to shelter in mice. Recent work has shown that escape to shelter is a goal-directed action that relies on memory of the shelter location, and which is controlled by a midbrain defensive circuit encompassing the superior colliculus and the periaqueductal gray. These circuit nodes can elicit the entire flight sequence to shelter, providing a unique entry point for investigating how spatial representations are converted into goal-directed actions. We aim to explain at the cellular and circuit level how the spatial vector to the shelter is encoded and transformed into shelter-directed flight actions.Our experimental strategy is to use loss-of-function approaches to identify circuit nodes that project to the superior colliculus and are necessary for escaping to the correct location, and perform neural activity recordings with high-density silicon probes and calcium imaging to determine how the spatial vector to the shelter is encoded and transferred to midbrain effector circuits. At the single neuron level, we will use whole-cell recordings to investigate connectivity and the biophysics of synaptic integration in circuits controlling the executi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Envisioning the Reward: Neuronal circuits for goal-directed learning'.

assistant: **Objectives**

Our ability to learn relies on the potential of neuronal circuits to change through experience. The overall theme of this project is to understand how sensory cortical circuits are modified by experience and learning. Recent results have shown that learning the association of a visual stimulus with a reward modifies neuronal responses in primary visual cortex (V1). However, the cellular mechanisms underlying these experience-dependent changes remain largely unknown. Computational and experimental studies suggest that feedback pathways are crucial for adapting sensory processing by task demands, together with local interneurons that gate feedback through dendritic inhibition. I will test the hypothesis that feedback projections from higher level areas selectively enhance task-relevant information in V1 and that this process depends on dorsomedial striatal (DMS) output.Toward this aim, I am using chronic two-photon calcium imaging to monitor the activity of neuronal sub-populations in mouse V1, before, during and after two types of visual experience: a passive exposure to a visual stimulus and a rewarded visually-guided task. Published and preliminary results indicate that the representation of task-relevant features is enhanced and stabilised in V1 during learning while responses to non-relevant stimuli are suppressed.This project is organized around 3 aims:1. To characterize top-down inputs to V1 neurons during passive and rewarded visual experience. 2. To characterize local circuits and single-neuron computation of task-relevant features within V13. To characterize the output of V1 neurons to higher cortical areas and DMS, during goal-directed learning.The expected results will show how behavioural training changes the neocortex to improve the encoding of behaviourally
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Development of a novel control technology for ensuring high quality Powdered Infant Formula' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Powdered Infant Formula (PIF) is a milk-like food intended to supplement or replace the milk of the baby's mother. The quality, nutritional profile and safety of PIF are intrinsic for the health and wellbeing of the babies and infants that depend on it for their survival and growth. Since most infant formulae are required to be instant, the preferred drying approach is typically designed to allow for product agglomeration during drying. The agglomeration improves the reconstitution properties. It is important that the degree of agglomeration and its compactness can be controlled. The identified key physical parameters governing the agglomeration process include granule size/shape and the key chemical parameters include moisture content. Properties of individual agglomerates determine bulk powder properties such as powder flowability, bulk density and solubility. These are important product quality characteristics since, for example, the product is measured out on a volume basis (in scoops) whereas nutritional requirements are provided on a mass basis. Thus any changes in particle properties post drying, during conveying and packaging will have implications.For dry blending, the ingredient distribution within granules and between granules has a critical effect on content uniformity, nutrient absorption rates and ultimately infant safety. The development of a hybrid technology that is capable of assessing the physical and nutritional characteristics of PIF in real time would significantly advance process control leading to greater product quality, process validation, and ultimately infant safety. In response the PURE-FORMULA project will develop a novel Process Analytic Technology capable of providing spatial measurements of moisture and ingredient identity from the formi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Colloidal Iron Oxide Nanoparticles for the REclamation of Toxic Metal Contaminated GROUNDwater Aquifers, Drinking Water Wells, and River Bank Filtrations', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The main objective of the presented innovation action is the first application and near-market replication of a novel water nanogeotechnology for the immobilization of toxic metals in groundwater aquifers, drinking water wells, and river bank filtration sites. The basic concept of our technology is the creation of an adsorptive in situ barrier for the immobilization of toxic metal contaminations. This barrier is made of iron oxide nanoparticles, which are injected into sediments as colloidal suspension, forming stable deposits there. Over the last 6 years, we have developed a novel technology for the injection of iron oxide nanoparticles (NPs) into groundwater contaminant plumes. The feasibility of this approach has been successfully tested in lab experiments and a scientific field application. Specifically, our approach addresses arsenic, barium, cadmium, chromium, copper, lead, mercury, and zinc, all of which are known major groundwater contaminants. Now, we want to bring this novel, green and near-market water eco-innovation into the European markets, and beyond. The very core of this effort is the performance of two industrial-scale applications of our technology at two different types of contaminated sites. This first application of our technological approach under field conditions is the major objective of REGROUND. By developing our technology into a market-ready application, REGROUND will globally transform the efforts to mitigate the risks posed by toxic metal contaminations to humans and ecosystems. The REGROUND technology, due to its low costs and wide applicability, will be made highly available. The near-market replication of our technology and subsequent commercialization efforts are an integral part of REGROUND. This will enable immobilization of toxic me