RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Flexible Air iNTerfAce for Scalable service delivery  wiThin wIreless Communication networks of the 5th Generation' (FANTASTIC-5G), addressing dissemination and exploitation.

assistant: **Impact**

5G will have to cope with a high degree of heterogeneity in terms of: (a) services (mobile broadband, massive machine and mission critical communications, broad-/multicast services and vehicular communications); (b) device classes (low-end sensors to high-end tablets); (c) deployment types (macro and small cells); (d) environments (low-density to ultra-dense urban); (e) mobility levels (static to high-speed transport).Consequently, diverse and often contradicting Key Performance Indicators need to be supported, such as high capacity/user-rates, low latency, high reliability, ubiquitous coverage, high mobility, massive number of devices, low cost/energy consumption. 4G is not designed to meet such a high degree of heterogeneity efficiently. Moreover, having multiple radio access technologies for multi-service support below 6GHz will be too costly.FANTASTIC-5G will develop a new multi-service Air Interface (AI) for below 6 GHz through a modular design. To allow the system to adapt to the anticipated heterogeneity, the pursued properties are: flexibility, scalability, versatility, efficiency, future-proofness. To this end, we will develop the technical AI components (e.g. flexible waveform and frame design, scalable multiple access procedures, adaptive retransmission schemes, enhanced multi-antenna schemes with/without cooperation, advanced multi-user detection, interference coordination, support for ultra-dense cell layouts, multi-cell radio resource management, device-to-device) and integrate them into an overall AI framework where adaptation to the above described sources of heterogeneity will be accomplished. Our work will also comprise intense validation and system level simulations.FANTASTIC-5G includes partners being active in forerunning projects like METIS, 5GNOW
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Oligomeric Plasticity Gating Mechanisms in Ion Channels', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Ion channels are transmembrane proteins regulating ion flux across cell membranes and are crucial for numerous physiological processes. Hence, ion channels are implicated in many diseases. To further drug development targeting ion channels, a comprehensive understanding is needed not only of their low-energy abundant states, but also of their rare and transient high-energy states, which play critical roles in channel function, regulation, and folding. The cutting-edge high-speed atomic force microscopy (HS-AFM) technique allows now to study such states, by providing simultaneously, on a single-molecule level, both dynamic and structural information of freely diffusing ion channels in the membrane, a feat that is currently impossible with other methods. Recently, I discovered using HS-AFM that the TRPV3 channel possesses a rare and transient pentameric state that reversibly interconverts with its canonical tetrameric sate, potentially conferring it new function. Here, I aim to investigate further the functional role and biological relevance of this finding, while concomitantly investigating if similar oligomeric plasticity occurs in other ion channels of diverse functions. Most particularly, I aim to investigate whether reversible oligomeric changes could be an additional mechanism for ion channels to modulate function. To do so, I will: 1) Discover reversible oligomeric transitions in other ion channels. 2) Reveal how reversible oligomeric transitions could modulate function. 3) Assess the physiological relevance and feasibility of such transitions. Positive results will lead to a paradigm shift in the way we think about the assembly, dynamics, and function of ion channels and introduce a novel new concept of how ion channels undergo conformational changes. Additionally
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Feasibility of new breast cancer genes as tumour markers for prognosis and management of breast cancer patients' under Fourth Framework.

assistant: **Concept**

Novel breast cancer genes essential for the development of sporadic breast malignancies have been identified by differential display and subtractive cDNA cloning strategies. The gene products of DIT1A12, an insulin-like growth factor binding protein, and T2E5, a human membrane protein, will be evaluated for their feasibility as tumour markers in breast cancer patient serum and biopsies. An Elisa method for larger scale screening of serum samples and an insitu hybridisation technique to examine gene expression in tissue specimen will be developed. If the genes are useful markers, they can be exploited for breast cancer detection kits. This joint venture of Canadian and British-German research teams will apply advances in molecular oncology in a disease oriented manner to give, if successful, oncologists a tool for early detection and prognosis of breast malignancies and subsequent women diagnosed with breast cancer or breast cancer predisposition increased chances for effective treatment and survival.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Quantum Phenomena in Optomechanical Systems' under Seventh Framework.

assistant: **Concept**

Cavity optomechanics is a flourishing research field concerned with the study of macroscopic objects in a regime where quantum mechanical effects become apparent. A strong interaction between the optical field and the mechanical motion of optomechanical resonators, usually mediated by radiation pressure, enables both new photonic technologies as well as fundamental experiments that are at the heart of quantum mechanics.This proposal aims to study micro- and nano-optomechanical systems cooled close to their ground state of motion to advance both fundamental and applied concepts in quantum optomechanics.A first aim is to study a recently developed optomechanical device based on a 2D photonic crystal defect cavity. In particular, we aim to cool this device down to its ground state of motion by embedding it in a Helium-3 cryostat and using radiation pressure induced laser cooling to reach its ground state of motion. The high optomechanical coupling strength measured on these devices promises to allow ground state cooling with moderate efforts.A second objective is to implement the technique of motional side-band spectroscopy, adapted from ion trapping experiments, to characterize the degree of occupancy of the ground state of motion of optomechanical resonators, providing a definite quantum-mechanical signature in these macroscopic objects.Finally, we will use the recently observed effect of optomechanically-induced transparency (OMIT) in microresonators, in which the optomechanical coupling induces a very narrow transparency window accompanied by a strong group velocity reduction, for storing and stopping light pulses in optomechanical modes.This proposal will allow the applicant, a physicist recently graduated with distinction from the Institute of Photonic Sciences (ICFO
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Australian plague locust population genetics and migratory behaviour'.

assistant: **Innovation**

Swarming locusts are crop pests of major importance, displaying unusual outbreaks with an irregular cycle and swarming individuals typical of a high-density distinctive form, the phase gregaria. Here we propose to complete the first ever large-scale population genetic analysis of a swarming locust, the Australian plague locust, Chortoicetes terminifera.   This species is the most devastating locust in Australia due to the frequency and severity of its outbreaks, as well as its widespread distribution across the continent. Genetic spatial structuring analyses will be combined with the evaluation:  (i) of the expression of the behavioural phase polyphenism, in which locusts respond to increased local population density by shifting from the solitaria condition, in which they do not aggregate or migrate, to the migratory, swarm-forming phase gregaria, and  (ii) of the local resource distribution patterns known to influence the migratory behaviour.   This study will considerably enhance our understanding of locust migration in an ecological and behavioural context. Knowledge from this project will be used to enhance preventative locust management in Australia by focusing monitoring and control efforts on critical swarm-forming populations and localities. This project will serve as a model for the application of population genetics to the management of swarming locusts around the world.   The proposal is founded on the fields of population genetics, resource ecology, and behaviour, providing the applicant a first rate training in a wide variety of disciplines. Collaborators with varied research skills in academic (University of Sydney and Centre for Biology and Population Management) and applied (Australian Plague Locust Commission) research are involved, strengthening the re
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Digital PLAtform and analytic TOOls for eNergy' (PLATOON).

assistant: **Innovation**

The digitalization of the energy sector enables higher levels of operational excellence with the adoption of disrupting technologies. The Energy Big Data framework of the modern smart energy networks provides an ideal ecosystem for knowledge exploitation from data. PLATOON pretends to deploy distributed/edge processing and data analytics technologies for optimized real-time energy system management in a simple way for the energy domain expert. The data governance among the different stakeholders for multi-party data exchange, coordination and cooperation in the energy value chain will be guaranteed through IDS based connectors. The project will develop and use the PLATOON reference architecture, COSMAG-compliant, for building and deploying scalable and replicable energy management solutions that contribute to increased renewable energy consumption, smart grids management, increased energy efficiency and optimised energy asset management. The PLATOON architecture and components are valuable for the different stakeholders of energy sector value chain, starting from electricity supplier, passing through the distributor, the aggregator, the ESCo until the End User. the project will be validated in 7 pilots of 4 countries that provide real Energy Big Data cases. It proposes to build the solution based on existing European standards and initiatives for managing the pilots’ data, for the access, models, interfaces, governance and sovereignty. It also foresees to report back the results to the different standardization working groups. PLATOON will facilitate the technology transfer into the market by a well established tendering process through Open Calls. The project will reinforce the European efforts for modernisation of the European electricity grid, because it focuses the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Patient-self-adaptive system for detection, recording and alert to caregivers of night-time seizures, linked to private cloud platform for patient tracking and big data exploitation.' in the context of a Horizon 2020 call.

assistant: **Objectives**

Approximately 50 million people worldwide have epilepsy, an illness characterized by recurrent seizures. The estimated proportion of the general population with active epilepsy is between 4 and 10 per 1000 people. Globally, an estimated 2.4 million people are diagnosed with epilepsy each year.When patients suffer generalized convulsions there is a risk for them of being injured or having a cardiac arrest. Caregivers (usually patients’ relatives) reduce this risk by being alert and applying techniques such as holding the patients, putting them in a certain stance or providing them with the prescribed drugs. The problem worsens when seizures occur at night-time.Caregivers usually sleep in the same bedroom as patients and cannot rest due to the constant concern, leading to inconveniences such as loss of privacy, bad resting and higher risk for patients. This project aims to improve the lives of people affected by epilepsy, both patients and caregivers, providing them with an effective and unobtrusive device to monitor patients and alert caregivers during night-time seizures.This project consists on a patient-self-daptive system to detect, video-record and alert caregivers of night-time seizures, linked to a private cloud platform for medical tracking of patients and big data exploitation. The main innovative characteristics of SEIZSAFE are:• Patient-self-adaptive and self-learning algorithm for seizure detection• Camera and cloud platform for doctors• Reduced-cost technology• Medical validationThe present project aims to expand SEIZSAFE in the European market. Considering a global market size of 1.2M epilepsy patients suffering night-time seizures, ENCORE foresees the uptake of 6.5% of the market in 5 years, which means 80,000 users by the end of 2022.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Prokaryotic RNomics: Unravelling the RNA-mediated regulatory layers' (PROKRNA).

assistant: **Concept**

Pioneering studies from the recent year, including those published by the PI of this proposal, are revolutionizing our perception of prokaryotic transcriptomes, and reveal unexpected regulatory complexity. Two central concepts are arising: the unanticipated abundance of cis-antisense RNAs overlapping protein coding genes, and alternative transcripts resulting from a dynamic behaviour of operon structures (where genes can be included or excluded from a polycistronic transcript in response to environmental cues). Understanding these phenomena holds a great potential for our ability to decipher how bacteria regulate their complex life styles and pathogenic behaviours, but their dynamics, regulatory roles, and effects on combinatorially increasing the regulatory capacity of the genome are completely unknown.The primary objectives of this proposed research are: i) to understand the extent, regulatory roles, and evolutionary consequences of cis-antisenseRNAs in prokaryotes; ii) to understand the regulatory code, combinatorial effects and dynamics of alternative operon structures; and, in parallel iii) to develop a unified framework for comparative prokaryotic transcriptomics.Our strategy is based on a combination of deep sequencing technologies, computational modelling and data analyses, systems biologyapproaches, and focused molecular biology experiments. We will identify the extent and the impact of these RNA-based regulatory layers in representative pathogenic and non-pathogenic species across the prokaryotic tree of life, study their functional and evolutionary consequences, and break the regulatory code controlling them. Our planned research has the potential of producingmethodological and conceptual breakthroughs in the emerging field of prokaryotic transcriptomics.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Nanodevices for Quantum Optics' (NAQUOP), addressing dissemination and exploitation.

assistant: **Impact**

We propose developing a nanodevice toolbox for single photon quantum optics. A scalable scheme to generate indistinguishable single photons, an interface to couple single photon polarization to a single electron spin and high efficiency single photon detectors represent the core of the scientific problems to be addressed in this project.We set the following research objectives: 1- Understand to what extent quantum dots can be made indistinguishable. 2- Interface coherently single photons to single electron spins via strain engineering in quantum dots. 3- Gain a better understanding of the limits to time resolution and detection efficiency of ultrafast superconducting single photon detectors.The proposed research effort will yield novel experiments: the realization of scalable indistinguishable quantum dot sources by frequency locking single quantum dots to atomic transitions, the demonstration of new selection rules in semiconductor nanostructures to couple photon polarization to the electron spin only, the development of ultrafast and high efficiency single photon and single plasmon detectors and their implementation in two photon interference and quantum plasmonics experiments.To carry out the work, multidisciplinary efforts where nanofabrication, quantum optics, semiconductor and superconductor physics will be merged to demonstrate the scalability of quantum dots for quantum information processing, providing crucial new knowledge in single photon optics at the nanoscale. The impact of the project will be important and far reaching as it will address fundamental questions related to the scalability of quantum indistinguishability of remote nanostructures.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Dehydration and hydrocarbon dewpointing of natural gas by membrane technology' (1994-1998).

assistant: **Concept**

The oil and gas industry is interested in using membrane based gas separation p rocesses for natural gas dehydration and hydrocarbon dewpointing. Membrane proc esses provide weight and space reduction, a flexibility regarding capacity chan ges and a clear reduction in the emission of aromatics. They allow short start- up times and they are suitable for offshore applications. The simple operation principle requires no coolants or additional chemicals and demands only a minim um of operation or maintenance. Developed and patented membranes for dehydratio n and separation of higher hydrocarbons from natural gas as well as a module sy stem are already available. The objective of this project is the development of new membrane based processes for natural gas dehydration and hydrocarbon dewpo inting. In order to get reliable performance and process data, tests will be ca rried out under real field conditions at different test facilities available wi thin the consortium. In these investigations improved membranes and module conc epts will be tested, which are especially optimised for high pressure and high volume flows typical for natural gas applications. Based on the data supplied b y the field tests, further improved simulation tools and the know-how that is p rovided by the industrial partners specific process designs will be developed. The knowledge which is obtained from these investigations will finally result i n the design and operation of a demonstration unit for natural gas treatment at one facility available within the consortium. In the consortium end-users from the European oil and gas industry will provide access to different test facili ties and will contribute to detailed process and economic evaluations. The plan t manufactures who are represented in this pro