RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'In vitro & biodistribution analysis of morphology-controlled polymeric gene delivery nanocarriers (POLYMORPH)' in the context of a Horizon Europe call.

assistant: **Objectives**

Gene therapy holds the potential to be an enabling technology to truly cure (rare) diseases by directly correcting errors in the patient’s genetic database underlying the disorder. For these corrections therapeutic nucleic acids (NAs) are typically used. However, the precise and efficient delivery of these NAs remains a critical bottleneck, hindering the full-scale clinical implementation of gene therapy. NAs are large, highly charged and unstable molecules, hampering transport and passing (intra)cellular barriers after administration. To mitigate this, NAs are typically packaged into nanocarriers, where lipid-based systems (LNPs) are the current state-of-the-art. Although an effective strategy to protect NAs, selective tissue targeting remains a tremendous challenge. Nanoparticles (NPs), including LNPs, tend to preferentially accumulate in the liver, limiting treatment of any disorder affecting other tissues and organs.The ERC PoC POLYMORPH project builds on the promising results of the original ERC Starting Grant project and aims to validate the use of nanoparticle (NP) morphology to redirect nanocarrier accumulation away from the liver. Morphological control of NA-loaded NPs is uniquely facilitated by a novel formulation strategy recently developed in the ERC Starting project. This novel approach has the potential to provide a superior alternative to the current, yet suboptimal, LNPs.POLYMORPH will achieve this validation through comprehensive in vitro studies and preliminary in vivo experiments, laying the groundwork for future clinical applications. The project is further strengthened by the active involvement of multiple stakeholders, including academic researchers, the pharmaceutical industry, medical centers, regulatory science experts, and a knowledge transfer
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Model-Driven Embedded System Design Environment\nfor the Industrial Automation Sector'.

assistant: **Concept**

The level of automation and system complexity in factories and plants increases steadily which results in difficult and less-productive system engineering. Therefore, the main target of the MEDEIA project is to radically improve the development productivity of embedded control systems for the European industrial automation sector. The project results will reduce their system design time by 25%, which will be reached by the following objectives: 1) Formal framework for model-driven component-based development of embedded control, 2) Easy understandable modelling method applicable for domain experts, 3) Integrated modelling of diagnostics, 4) Integrated simulation and verification of systems design, 5) Automatic, embedded platform specific code-generation for the deployment of control software to heterogeneous hardware and 6) Proof–of-concept demonstration. <br/>The European industrial automation industry will benefit from the MEDEIA results. The project will be applicable for this sector and it will support them with a powerful method to design and maintain long operational installations as well as automation solutions with rapidly changing demands. To ensure a wide usage of the project results it is planned to standardize the MEDEIA method and to provide an open source design tool. Project results will improve the competitiveness of European companies through increased productivity of system development by the provision of a novel model-driven design method for embedded control and diagnostics using Automation Components as major design part. Furthermore, such results will reinforce the European scientific and technological leadership.<br/>A major factor for successful projects especially for transnational projects is the project team. Therefore the project partners are
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Re-Making Sex: Observing, Representing, and Explaining Sex Difference in Early Modern European Vernaculars' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Since Thomas Laqueur's controversial arguments in Making Sex: Body and Gender from the Greeks to Freud (1990), scholars of gender history have debated the shift from so-called ""one-sex model,"" in which the bodily differences between male and female human beings were thought to exist on a continuum from a fully formed human male body to an inferior, ""less male"" female body, to the modern ""two-sex model"" at the beginning of the nineteenth century. Building on critiques of Laqueur's arguments, this project analyzes vernacular texts treating sex differences, hermaphroditism, and human reproduction circa 1600-1800 in German, French, English, and Spanish in medical and non-medical sources. Although the ""one-sex model"" did not dominate premodern and early modern medical discussions of sex difference as Laqueur argues, in the learned Latin traditions taught in medical faculties in universities, European vernacular literatures in the seventeenth and eighteenth centuries paid special attention to specific visual and spatial analogies between male and female anatomies and debated the possibilities and implications of sex ambiguity and sex change. The project analyzes how vernacular texts described the determination of sex difference, the extent to which male and female bodies were different, and in what sense, what the stakes were of failing to determine the maleness or femaleness of a body, and the specific social, political, and religious anxieties about gender roles and norms, the family, literacy, sexuality, and religious piety were expressed and developed in the discussions of sex difference and determination.""


**Keywords:** History of medicine,  history of sex, gender, and sexuality,  religion and gender
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Demonstration of a sustainable circular-by-design manufacturing system based on additive manufacturing' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

DIAMETER aims to facilitate the implementation of a circular economy within the metal manufacturing sector through the development of hybrid manufacturing systems based on additive manufacturing. The Consortium will develop a set of digital tools to improve the design, optimise the manufacturing process and ease the implementation of circularity strategies (remanufacturing, refurbishing, repairing and recycling) by the additive manufacturing industry. To support those tools, we will develop a novel AI-assisted algorithm able to calculate both the ecological and economic impacts of a process to assess its sustainability. This AI-assisted algorithm will rely on experimental data, from process monitoring and part characterisations, and process simulation, covering pre-processing machining, additive manufacturing and post-processing machining. We will integrate these tools into a first platform, called DIAgonal, to facilitate the uptake by the industry. The platform will integrate the European Digital Product Passport by enabling the use of supplier data for more accurate ecological impact estimations and allowing the upload of experimental data to enrich product transparency on origin, materials, and recyclability. We will develop a second platform, DIAdemia, to support the upskilling of the workforce through interactive training courses, workshops, and exercises. Overall, DIAMETER will contribute to reducing the manufacturing sector's carbon footprint, enhancing recycling, developing a greener Industry 4.0 and promoting local production.


**Keywords:** circularity, additive manufacturing, process, sustainability, machining, industry, digitalisation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Cognitive variability emerging from gut microbiota diversity in an insect society', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The animal gut microbiota is diverse, hosting multiple bacterial species whose presence and abundance differ between individuals. Over the past decade, evidence that the gut microbiota influences its host cognitive functions has accumulated but mostly relied on correlative studies in humans and laboratory research involving microbiota-free rodents. It is therefore unclear whether inter-individual variation in gut microbiota composition supports cognitive variability in natural populations of non-human animals. This project will leverage the honey bee model to bring ecological perspectives on the study of the microbiota-gut-brain axis while elucidating the neurobiological mechanisms by which gut microbiota diversity drives cognitive variability. Honey bees offer a unique opportunity to finely manipulate gut microbiota composition using reconstituted gut bacterial communities. Their social life fosters cognitive variability among individuals and provides an ideal system for assessing the ecological relevance of the microbiota-gut-brain axis in a real-world context. The keystone of our naturalistic approach will be the implementation of mini hives allowing honey bees with reconstituted gut bacterial communities to forage in their natural environment. We will search for bacterial species and their metabolic products affecting the neural processes supporting cognitive functions and foraging efficiency. We will investigate the impact of gut microbiota composition and its associated cognitive variability on bees foraging behaviour and the fitness of the hive. This multidisciplinary project will provide groundbreaking insights into the fields of cognitive ecology, neuroscience, gut microbiology, host-microbe symbiosis, and honey bee health. Through this holistic approach, I aim
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'A High-Sensitive Green Localization System for High-Speed Self-Driving Vehicles' under Horizon 2020.

assistant: **Concept**

Among the main goals of Intelligent Transportation Systems are (i) safety: reducing threats encountered due to human impact, and (ii) efficiency: providing transportation opportunities in an ecologically and economically sustainable way. Self-driving vehicles (SDV) have the potential to achieve both goals, for which localization (i.e., the determination of the positon and velocity of the vehicle) is of key importance. Localization is challenging due to the variety of conditions (weather, clutter, obstructions) that may impede different sensors, as well as the strict latency requirements. Accurate and fast localization is a necessity for providing crash-safe high-speed SDVs. Furthermore, reducing energy costs introduced by the continuous localization process is required for reducing the frequency to charge an SDV. Current SDV localization technology is insufficient in meeting these three performance measures at the same time, requiring a different approach for high-speed SDVs. This project proposes a high-sensitive fast green relative localization system, called as GREENLOC, which obtains and shares the relative location of surrounding vehicles and road-side units by ultra-wideband cross-layer communications in a multi-hop vehicular ad-hoc network. GREENLOC is the first localization system, which enables crash-safe SDVs driving not only on highways close to speed limits, but also in congested low-speed traffic. Moreover, GREENLOC is the first localization method that works accurately even in difficult weather conditions. This project has the potential to shift Europe forward in the international competitive race of SDVs, making crash-safe high-speed SDVs possible, which in turn has the potential to solve the traffic congestion problem. Besides, this fellowship is an exce
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Quantum Hall states in ultracold atomic gases' (2007-2013).

assistant: **Concept**

The fractional quantum Hall effect is one of the most intriguing quantum effects and the topic of much study in condensed matter physics. In the field of ultracold atomic gases, it has been a long endeavor to reach an experimental regime in which the associated strong correlation phenomena can appear. In this project, we want to explore two separate roads towards this regime. In a bulk system, we want to reduce the atom number to mesoscopic values in order to reach to required small fraction of atoms to vortices. In a lattice system, we want to create the recently proposed ""optical flux lattices"", which exhibit bands with non-zero Chern number, and thereby for the first time realize lattices with artificial gauge fields. In both cases, we want to use a single-atom imaging technique to study the ensuing strongly correlated states.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Chemists Everywhere' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The ChemEve: Chemistry EveryWhere proposal consists in two different activities. The first activity consists of seven main Events on the 23rd September 2011, which will gather around 15000 people, organised by seven public entities around Spain: Girona, Murcia, Burgos, Las Palmas, Oviedo,  Valladolid, and Mallorca. The second activity consists on a Drawing Competition, which will be performed before and after the 23rd event. Special emphasis will be done on the 2.0 tools, called Researchers 2.0, using games and videos edited in the previous edition of Reseachers’ Night. These tools, together with the Drawing Competition, will be used to disseminate 23rd Event Activities.The main objective of the project is to enhance the recognition of researchers and their role in society. Being 2011 the International Year of Chemistry (IYC11) each researchers’ work will be related with chemistry using some experiment, letting the general public know that researchers are “common people”. The role of the project will go around showing that Everything is Chemistry and Chemists are Everywhere. For this purpose, the Communicative facet of researchers together with some hands-on experiments will be used to bring them closer to the large public by presenting researchers as “common people. The project will be implemented using different activities:1. Researcher 2.0: This activity will be focused in: Scientists explaining their work and gallery of experiments and games.2. Drawing Competition: Based in previous experiences of the Researchers’ Night edition, a drawing competition will be held. Their analysis will be used to tackle stereotypes about researchers.3. Researchers’ Night: Chemists EveryWhere: A Researchers’ fair will take place during the whole Event, where hands on experiments, works
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Automated Mass Production of SOC Stacks'.

assistant: **Concept**

AMPS project brings together the leading European companies in Solid Oxide Fuel Cell and Solid Oxide Electrolyzer manufacturing value chain. The project includes automation companies (Rocksoft, Smartal) and manufacturing equipment producers (SITEC, Haikutech, Dosetec) as well as cell manufacturer (Elcogen AS) and stack manufacturer (Elcogen oy). The project is motivated by their strong commitment to develop their products and services and commence real mass-manufacturing. The industry partners are supported by research institutes VTT, Polito and VUTS.The high-level AMPS objectives are:1.Automated high-speed cell production with integrated quality control2.Automated high-speed interconnect plate production and coating with integrated quality control 3.Automated high-speed stack assembly with integrated quality control    4.Complete component tracking and optimized mass-manufacturing by using virtual twins 5.Assessment and demonstration of target stack manufacturing cost of <800 €/kWel at production volume of 100 MW/year  6.Establish European supply chain of SOC manufacturing equipment  Successful dissemination of the AMPS results is in the core of the participating companies business, as they are selling stack components and associated manufacturing equipment for many other companies than just AMPS partners and therefore want to spread the knowledge of the developed solutions and manufacturing methods and equipment.


**Keywords:** Hydrogen, Fuel Cells, Electrolyzer, Manufacturing, Quality Control
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'The COMET (Core Outcome Measures in Effectiveness Trials) Initiative'.

assistant: **Objectives**

Clinical trialists often struggle when trying to choose the outcomes to measure which would be of most use to the patients, practitioners and policy makers who will use their research to help them make decisions. These difficulties are passed on to those producing and reading systematic reviews, many of whom have experienced the frustration of finding that the original researchers either did not measure certain outcomes or measured them in such different ways that it is difficult or impossible to compare, contrast or combine the studies.A core outcome set is a set of outcomes which should be measured and reported, as a minimum, in all clinical trials for a specific condition. Core outcome sets (COS) could have implications across all areas of health research, reduce heterogeneity between trials and lead to research that is more likely to have measured relevant outcomes. COS would enhance the value of evidence synthesis by reducing the risk of outcome reporting bias and ensuring that all trials contribute usable information.The COMET (Core Outcome Measures in Effectiveness Trials) Initiative aims to develop an international network of individuals and organisations interested in the development, application and promotion of core outcome sets. Working together will enable COS to be developed efficiently, leading to improvements in the quality of clinical research much earlier than would otherwise be the case. The objective of this proposal is to develop COMET’s strategic plan to: (i) increase the number of COS developed using evidence-based methods, (ii) increase their impact on the quality of research-based knowledge, by raising awareness and increasing implementation, (iii) establish methods for standards of COS development.COS will shape the future of European and inter