RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'European Media and Immersion Lab'.

assistant: **Objectives**

EMIL, the European Media and Immersion Lab, is a joint effort of four major European academic institutions (Aalto University, Filmakademie Baden Württemberg, Universitat Pompeu Fabra and University of Bath) to form a Pan-European XR Lab network to accelerate development of virtual, augmented and mixed reality technologies, content, services and applications for the media. EMIL will establish a physical and virtual infrastructure (EMIL Nodes), supported by research excellence, technological, creative expertise and wide contact networks to bring together interdisciplinary actors in the XR-field; engineers, designers, journalists, filmmakers, game developpers, programmers, artists, researchers, entrepreneurs and investors, from start-ups, SME’s and global corporations. EMIL will launch and coordinate FSTP projects and support this interdisciplinary community to accelerate XR-development all across Europe. The projects will be prototyping advanced solutions for the creation, distribution and consumption of new immersive and innovative products for media and related creative industries. FSTP projects can tap into the latest scientific research knowledge demonstrated in the EMIL nodes’ Lighthouse projects that exhibit excellence in Narrative Media Production, Smart Garments, Animation, VFX, Embodied Interaction, Digital Cultural Heritage, Digital Health, Motion Capture/Analysis, and technological XR-development. The FSTP projects and Lighthouse projects will quickly provide concrete cutting-edge products and services for the benefit of the European Media industry. However, EMIL’s true ambition and impact lie beyond the limitations of these projects and in the establishment of a permanent Pan-European XR network and community that will continue bringing new innovations in medi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Decoding the neural mechanism of human spatial cognition using behavioural and hemodynamic signals' under Horizon 2020.

assistant: **Concept**

The aim of this research is to understand space constancy, that is the mechanisms used by the brain to build a stable and continuous percept of our environment despite frequent movements of our sensory receptors (eyes, ears). For example, each time we move our eyes, the image of the outside world sweeps across the retina, yet we see the world as stable. Studies using single cell recording in animals have shown that some visual neurones predict what the world will look like after an eye movement by remapping their receptive fields to the place they will occupy following the movement. In my previous studies I developed behavioural tools that allowed me to model remapping in human as an attentional process. Even though my findings in humans were largely consistent with the results obtained from single cell recordings in animals, there was no possible way to establish a direct link between these data. Recent methodological advances in functional imaging, both in terms of techniques and data analysis make this possible. By combining my tools with novel imaging analysis of human population receptive fields, I aim to determine the mechanisms our brains use to stabilise our percept of the world for visual and auditory objects. Using hemodynamic (fMRI) and behavioural (gaze recording) signals I will decode the organisation of the multi-sensory spatial maps. I aim to determine the role of attention for space constancy, to establish innovative methods and procedures for investigating human spatial cognition, and to reconcile human and animal neurosciences findings by providing precise neural information of the maps and the neural mechanisms of human spatial navigation. This interdisciplinary project will constitute a unique opportunity to combine my expertise with state-of-the-art
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Intellectual Life and Learning on Rhodes (168BC-AD44)' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

ILLR is the first intellectual and cultural history of Rhodes centered on a seminal period of its cultural prominence between itsalliance with Rome (164 BC), where its financial and military power was curtailed and it became semi-autonomous, and itsincorporation into the province of Asia (AD 44) by the Emperor Claudius. Using a combination of actor-network/socialnetwork theory and intellectual history with literary and material evidence, ILLR shows the transformation of Rhodian andGreek identities from a predominately economic and political power to a cultural one in a Greek and subsequently Greco-Roman world, and Rhodes’ part in the creation of the Classics and Greco-Roman culture.ILLR demonstrates Rhodes’ pivotal and under-appreciated role as an important intersection within networks of learning, byanalysing ancient intellectual life in all its forms (e.g. philology, history, philosophy, the sociology and anthropology ofknowledge). Consisting of a monograph and two articles, it examines the preservation and study of heritage, thedevelopment of poetry, scholarship, philosophy, and rhetoric, and their subsequent influence on Greeks and Romans.My main research interests are Greco-Roman literary history, Greek poetry and music, ancient scholarship, and fragmentaryliterary texts. ILLR will advance my career and strengthen my profile as a researcher by allowing me to expand my researchinterests to Latin literature and learning, Greek epigraphy, and Greco-Roman oratory, and allow me to disseminate theseskills through teaching and further research. ILLR serves as a point of comparison, and, conceivably, of inspiration, whendealing with analogue features of our contemporary world. These features include the mobility of students and scholars, theformalisation and diversificatio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Confronting Social and Environmental Sustainability with Economic Pressure: Balancing Trade-offs by Policy Dismantling?' to be submitted under Seventh Framework.

assistant: **Abstract**

CONSENSUS aims to improve our understanding of trade-offs and synergies between economic, environmental and social aspects of sustainable development. In so doing, the project applies a selective focus in order to shed light on several issues that are of particular relevance in this respect – both in practical and analytical terms. First, the project places particular emphasis on a systematic analysis of the interlinkage between different levels of economic pressure and social and environmental policy. Second, in line with the political emphasis on better regulation and deregulation, the project applies a highly innovative perspective on policy change and sustainable development. Third, this interlinkage between economic pressure on the one side, and environmental and social sustainability on the other, is analyzed on the basis of a systematic comparison across 25 OECD countries over a period of thirty years (1975-2005)  Fourth, this focus offers the opportunity for a comparison of regulatory adjustments across different policy areas. The focus on two 'crucial' policy fields – social and environmental policy – allows us to study whether regulatory responses to economic pressures differ between these areas. Fifth, with regard to environmental and social policy, we focus on those subfields that have been identified as priority areas of sustainable development  The projects proceeds in the following steps. In the first step, the theoretical framework will be further elaborated. In the second step, a quantitative analysis of the major driving forces of policy dismantling will be acrried out. For this purpose, cross-national data on social and environmental policy dismantling for the period from 1975 to 2005 will be collected. In the third part of the study, theoretiaccly in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The role of microbial and invertebrate activities in shaping Alpine Soil Respiration: current state and future scenarios' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The belowground production of CO2 in soil (soil respiration, SR) represents an important terrestrial carbon source. Being correlated with soil temperature, SR is expected to exacerbate climate change. In addition, SR is expected to change considerably and in a patchy manner especially within the Alpine area, reflecting the effects of altitude, land use and climatic conditions. Previous studies measuring SR along altitudinal gradients, however, struggled with strong differences in environmental influences and with distinct unique faunal and microbial communities among samples.The grand ambition of ACTI-RESP is to provide in-depth knowledge and quantitative information on how microbial and invertebrate communities are influenced by altitude, land use and climate change, and on how microbial activity shapes SR. To quantify the pure effect of altitude and to investigate the effects of climate and land use, I will combine field observations and a manipulative experiment within terraXcube, a facility allowing manipulations of multiple conditions including air pressure to mimic different elevations.Thereby, I aim to further test the advantages of studying intracellular DNA (iDNA) as opposed to the generally studied environmental DNA (eDNA). Being composed by considerable amounts of extracellular DNA, eDNA does not only contain information about intact and active cells (intracellular DNA, iDNA) but also about extracellular DNA from species that might not be recently present. Here, I will study microbial agents actually shaping SR by extracting iDNA, by performing qPCR and 16S rRNA sequencing and by comparing the results to eDNA as well as RNA-based results.In doing so, I aim to - define climate change-related alterations in SR- jointly examine soil invertebrates and microorgani
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'User-centric solutions for a flexible and modular manufacturing in small and medium-sized shipyards' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

EU shipbuilding leading edge relies in the complexity, quality, customization, delivery time and lifecycle services (e.g. in situ maintenance, repair and retrofitting) of the vessels manufactured. However, in the last decade, EU small and medium-sized shipyards (SME) have experienced a competitive drawback in their market segments due to an increase of competition from other global regions that benefits from lower labour costs or higher automation degree. Moreover, SME shipyards must also overcome a major impediment related with capital investment that can overwhelm the part cost for shipbuilding. As a result, current automation solutions based on large monolithic equipment, are not still valid for increasing productivity in SME shipyards.Therefore, shipbuilding, and especially SME shipyards, needs novel cost-effective, reconfigurable, modular and flexible worker-centric methodologies capable of improving worker’s performance and ensuring quality and precision in the execution of the labour-intensive tasks.Mari4_YARD aims the implementation of a portfolio of worker-centric solutions, by relying on novel collaborative robotics and ubiquitous portable solutions, enabling modular, reconfigurable and usable solutions targeting the execution of labour-intensive tasks by preserving industry-specific workers’ knowledge and skills.Moreover, replicability and early-adoption of the portfolio of technologies by other SME-shipyards is ensured through several actions on training, technology assessment, benchmarking… by establishing a pan-European network of Didactic Factories, offering general-purpose testbeds and showrooms, as well as providing upskilling and re-skilling of shipyards workforce.To further maximise the impact, Mari4_YARD plans to use synergies with complementary Euro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Gene Expression Regulation and Cancer' (MISWI) targeting Seventh Framework.

assistant: **Abstract**

Cancer remains the most predominant cause of premature death in Europe. It constitutes a major public health problem with 1.28 million predicted deaths in the European Union in 2011. Changes in the gene expression patterns are a key feature of cancer cell transformation through an increase in expression of genes that promote carcinogenesis (oncogenes) and/or a decrease in expression of genes that prevent it (tumour suppressor genes). Chromatin-structure and microRNAs (miRNAs) both play important roles in this process and have been found to be critical in the development of human pathologies.DNA is packaged inside cells through a scaffold of proteins, constituting the chromatin. The chromatin not only has a structural role, but it also plays an active role in other processes including gene expression. The SWI/SNF complex is an ATP-dependent chromatin-remodelling complex that uses the energy from ATP hydrolysis to modify the interactions between DNA and histones. In this way, the SWI/SNF complex can render the DNA accessible or inaccessible to the transcription machinery. Ever increasing evidence demonstrates that some components of the SWI/SNF complex act as tumour suppressors and their dysregulation is involved in human cancer development.MiRNAs are a recently discovered class of small RNA molecules that regulate gene expression at the post-transcriptional level. Due to their small size and unusual nature, miRNAs were not discovered in humans until 2000. Today, over one thousand miRNAs have been identified in the human genome. Aberrant biogenesis and/or expression of miRNAs has been linked to human diseases including cancer.Pioneering reports suggest a functional relationship between the SWI/SNF complex and miRNAs. MiRNAs regulate the expression of chromatin remodelling
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Spin Glasses, Learning, and Optimisation in High Dimension' (SLOHD) under Horizon Europe.

assistant: **Objectives**

This project aims at tackling problems in statistical mechanics, with a primary focus on spin glasses, followed by an exploration of machine learning related questions. Spin glasses, initially studied in the 1980s using non-rigorous methods by theoretical physicists, revealed complex behaviours which were previously unknown: They conjectured that the phenomenon they depicted should be present in many more models such as neuronal networks. From a mathematical perspective, spin glasses are disordered systems where each ""spin"" can be seen as a random variable, interacting with others through a network of complex, often conflicting, interactions. Recent recognition in the field, with Giorgio Parisi winning the Nobel Prize in 2021 and Michel Talagrand receiving the Abel Prize in 2024, highlights the importance of spin glass studies. However, many questions remain unanswered, particularly regarding the mixed SherringtonKirkpatrick model: the phase transition between the high and the low-temperature regime is not known rigorously. One key objective of the fellowship is to explore this phase transition mainly through a dynamical approach by viewing the disorder in the Hamiltonian as different Brownian motions, with temperature playing the role of time. Beyond spin glasses, the project will also investigate neural networks (specifically, one-hidden-layer models with a large but finite number of neurons): the algorithms underlying their training are still not fully understood, and we aim to elucidate why, despite the non-convexity of their objective, do they converge to a desirable solution? Although spin glasses and machine learning may seem unrelated at first glance, it is believed that many probabilistic techniques from spin glass theory can be applied to understanding machi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'High resolution three-dimensional structure of the nicotinic acetylcholine receptor' under Fourth Framework.

assistant: **Concept**

The overall objective of this project is to determine the three-dimensional structure of the prototypic neurotransmitter receptor, the nicotinic acetylcholine receptor (AChR), at high resolution, in order to understand the structural basis of ion channel function, using advanced electron crystallographic, NMR and X-ray crystallographic methods, combined with monoclonal antibody and ligand labelling. Currently, the best available image of a neurotransmitter receptor is that of the AChR at 7.5A resolution, obtained by one of the participating laboratories. Imaging this model ion channel at high resolution requires further development of the available technologies. We aim to improve the overall structural description of the receptor molecule, to identify specific critical sites of the molecule, to find out how this ion channel achieves its specific ion selectivity and transport rates and to understand, in physical terms, how it opens, closes and desensitizes in response to acetylcholine. Our objectives will be achieved by the further development, application, and combination of advances in technologies we have recently developed. These include a wide variety of biochemical and biophysical techniques, i.e. improved 2D-crystals, new routes of 2D crystallization, region-selective crystallization, efficient correction of distortions in the 2D crystals, demi-automatic acquisition of electron crystallographic data, trapping of different conformational states, 2D- and 3D-NMR, recombinant monoclonal antibodies, soluble recombinant polypeptides and powerful instrumentation. Our objectives will be mediated by the following work-packages: a. Production of recombinant monoclonal antibody fragments for use as tools. b. 2D-crystallization of AChR in native membranes and artificial lipid
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Mechanisms of Cell Extrusion controlling Tissue Homeostasis in the Intestine' (MCExtrusion) targeting Horizon 2020.

assistant: **Abstract**

The intestinal epithelium undergoes continuous self-renewal through coordination of cell proliferation in the crypt and cell removal in the villus region. The aim of this project is to elucidate the mechanisms controlling the removal of differentiated cells from the villus. Preliminary data indicate that most extruding cells are non-apoptotic suggesting alternative mechanisms regulating this key homeostatic event. Cells might either commit to extrusion through specific differentiation programs or local tissue mechanical constraints might force the extrusion of otherwise indistinguishable cells. Feedback between cell fate and mechanical constraints can be also envisaged. Here I propose to identify genes that control cell extrusion by analyzing the dynamic transcriptomic signature of the mouse intestinal epithelium using nascent mRNA sequencing (scEU-seq) and pharmacologic inhibition of candidate pathways in intestinal organoids. Target genes will be functionally validated by a CRISPR-Cas9-mediated knockout screen. This analysis will be flanked by experiments investigating a potential role of tissue-scale mechanical forces in cell extrusion. I will measure the mechanical properties of the intestinal epithelium and obtain a detailed description of the morphological dynamics characterizing cell extrusion using live imaging and 3D-shape reconstruction. Precise manipulation of cortical tension by means of laser ablation combined with subcellular optogenetics will be used to functionally perturb tissue mechanics and reveal the impact of cell contractility and tissue tension on the extrusion process. Collectively, this project will help understanding how tissue homeostasis in the intestinal epithelium is maintained and dissect the relative contribution of genetic signaling circ