RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'A European database of Indicator Coastal Communities.' (1994-1998).

assistant: **Concept**

The main objective of this project is to bring together experts from different countries, academic disciplines and industry sectors, all persons who have been engaged in former projects with the aim of creating better and more policy-relevant planning instruments for European coastal areas.Sub goals are:1. to identify fisheries dependent areas in Europe and highlight those which are most economically and socially vulnerable; 2. to diagnose the most important macro processes (from fisheries policy, environmental change, technological change, etc) expected to influence these areas in the next decade; 3. to select a number of indicator coastal communities with fisheries dependence for comparative in-depth studies;4. in this process, to use some of the harmonised indicators that have been developed for European rural areas with fisheries dependency, and 5. to assist those responsible for the management of the CFP with tools that will enable them more easily to assess the social and economic consequences of alternative management options2. METHODOLOGY AND RESEARCH TASKSMethodology:The main outcome of this project shall be a database material with special emphasis on the socio-economic conditions in European coastal areas with fisheries dependence. The structure of the database consists of three elements: a macro-material with aggregated numerical information, a micro-material with both statistics and other types of information and the front-page": an Internet presentation. The Internet presentation will be developed in both volume and complexity throughout the project. In the start of the project the Internet presentation will appear more like a framework with maps and national statistics. At the time of completion users from all over Europe will have access to a substantial
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'HIV-1 sensing and signaling in dendritic cells'.

assistant: **Objectives**

HIV-1 is a major global health problem with over 2 million new infections every year, and although antiretroviral therapy is effective, chronic infected patients suffer from severe co-morbidities due to immune dysfunction. With the proposed SENTINEL project, I aim to identify novel strategies to enhance innate antiviral immunity to HIV-1 to limit establishment and progression of chronic disease. Our novel data strongly suggest that induction of antiviral innate immune responses in dendritic cell subsets delays disease progression and improves survival in chronic HIV-1-infected patients. Current paradigm suggests that HIV-1 evades innate sensing in dendritic cells and that this underlies immune dysfunction. However, our innovative data demonstrate that HIV-1 actively suppresses a novel innate sensing mechanism and antagonizing this HIV-1 suppression by drugs strongly enhanced antiviral immunity. Strikingly, we identified a gene polymorphism in a component of the novel HIV-1 sensing machinery, rendering the pathway insensitive to HIV-1 suppression; this polymorphism is associated with delayed disease progression and improved survival in HIV-1 patients from the Amsterdam Cohort Studies. Thus, I hypothesize that therapies counteracting the suppression by HIV-1 will enhance antiviral immunity and restore immune dysfunction in chronic patients. Within this SENTINEL project, novel targets for HIV-1 therapy will be identified. As we identified proto-oncogenes involved in the suppression of innate immune responses by HIV-1, we will also screen clinically approved anti-cancer drugs as novel therapies to enhance the innate immune responses to HIV-1. Our exciting data strongly underscore the innovation and feasibility of the project. The unique expertise of my group in elucidating
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Monitoring of damage in historic tapestries' (MODHT) under Fifth Framework.

assistant: **Objectives**

Historic tapestries will be characterised by an interdisciplinary consortium of conservation scientists, curators, and scientists to provide markers of physicochemical change and hence damage assessment. Curators from major European repositories of historic tapestries are involved and this reflects their mutual concern for the optimum future preservation of these increasingly fragile materials. Model of tapestries and their components wool/silk/metal thread/dyes/mordants) will be made according to traditional practices and then artificially aged. Model and historic samples will be characterised by an integrated chemical/materials science approach. A new understanding of degradation will be obtained and changes in fibre strength and colour will be described for the first time in chemical terms. The state of the fibre and fabric are of vital importance for the overall mechanical integrity of tapestries and will determine future treatment.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Optically controlled carrier and Nuclear spintronics: towards nano-scale memory and imaging applications' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Carrier spin states in semiconductor nano-structures can be manipulated with fast optical pulses via the optical selection rules. The electron and hole spins in quantum dots interact strongly with the nuclear spins in the host material via the hyperfine interaction. This allows a new, versatile approach to nuclear spintronics, namely applying fast optical initialisation to carrier states and subsequent transfer via dynamic nuclear polarisation (DNP) of the spin information onto long-lived nuclear spin states, with promising applications in quantum information science and novel nuclear magnetic resonance (NMR) techniques.This project aims to develop new, efficient optical pumping schemes to maximise DNP by going beyond the established Overhauser effects, investigating the possibility of self-polarization and phase transitions of the nuclear spin ensemble. An innovating aspect of this proposal is to use valence state engineering to tailor the highly anisotropic dipolar interaction between nuclei and holes, which can lead to novel, non-colinear hyperfine coupling.The next innovation proposed is the development of an all-optical technique AONMR that does not require any radiofrequency (rf) coil set-up capable to control mesoscopic spin ensembles. Contrary to standard NMR techniques based on the generation of macroscopic rf-fields, AONMR can address the nuclear spins in one single nano-object via resonant laser excitation.A further important target is to use quantum dots and other carrier localisation centres as efficient sources of DNP generation and to carry out a detailed study of the diffusion of DNP throughout the sample and finally across the sample surface, varying key sample (chemical composition, strain, substrate orientation) and experimental parameters such as tem
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Local Governance and Dynamic Conflict in Developing Countries' (GOVERN).

assistant: **Innovation**

This proposal is divided into two main strands.The first strand seeks to understand the effects of local marginal institutional change in autocracies. In particular, we will examine the introduction of local democracy in rural China. Our first contribution is to collect a representative panel of villages in rural China. With this unique data we will examine three main questions: First, we will establish the effect of the introduction of local elections on policies that are determined at the village level: land allocation, tax collection, public good provision and the enforcement of the one child policy. Second, the data will provide a unique opportunity to explore the interaction between formal and informal institutions of accountability by leveraging our information on social infrastructure in these villages. Third, we will determine whether leaders' characteristics change with the introduction of elections.  These unique data will also set the stage for examining many other recent policy reforms in rural China.The second strand of the proposal seeks to focus the formal conflict literature to the study of insurgencies, a currently prevalent form of organized violence in developing countries. To capture the basic characteristics of these conflicts, we need models that allow for (i) meaningful conflict dynamics, (ii) a central role for the non-combatant population, (iii) fundamental asymmetry between government and insurgents and (iv) economic transfers and service provision as a strategic ability of the contenders. To reach this goal we will build a series of models whose main contribution to the formal literature of conflict is the introduction of tools from the dynamic principal agent framework. Several building blocks will be analyzed before integrating them in a coh
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Demonstrators for Conversion, Reactor, Radiator And Thrusters for Electric Propulsion Systems' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The objective of this proposal is to investigate the necessary demonstration activities in order to mature technologies for nuclear electric propulsion (NEP) systems that is considered one of the key enabler to allow deep exploration and science missions both manned and unmanned. The DEMOCRITOS projects aims to define three Demonstrator Concepts in regards to NEP technologies: 1. Detailed preliminary designs of ground experiments that will allow maturing the necessary technologies in the field of MW level nuclear electric propulsion. The project will investigate the interaction of the major subsystems (thermal, power management, propulsion, structures and conversion) with each other and a (simulated) nuclear core providing high power, in the order of several hundred kilowatts. 2. Nuclear reactor cost studies and simulations to provide feedback to the simulated nuclear core of DEMOCRITOS ground experiments as well as conceptualize the concept of nuclear space reactor and outline the specifications for a Core Demonstrator, including an analysis of the regulatory and safety framework that will be necessary for such a demonstration to take place on the ground.3. System architecture and robotic studies that will investigate in detail the overall design of a high power nuclear spacecraft, together with a pragmatic strategy for assembly in orbit of such a large structure coupled with a nuclear reactor.Additionally, the project partners will define a programmatic plan, insuring that the demonstrators can be built, tested, and reach the established ambitious objectives, this with a clear organization between international partners and with costs shared in a sustainable way. DEMOCRITOS aims to form a cluster around NEP related technologies by organizing an international workshop
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Effect of PTPN22 on Treg to Teff equilibrium in human and murine autoimmune diabetes' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

Type 1 diabetes (T1D) is a chronic inflammatory disease, where predisposing genetic factors along with environmental influences result in loss of immunological tolerance and destruction of insulin-producing beta cells. Genetic studies have identified three main T1D susceptibility loci, the human leukocyte antigens (HLA), insulin and most recently PTPN22, which encodes for Lyp/Pep, a lymphoid tyrosine phosphatase. A single nucleotide polymorphism (SNP) in PTPN22 at codon 620 leads to one amino-acid substitution, Arg to Trp (R620W), associated with an increase in T1D risk. A perturbation in the effector (Teff) to regulatory T cell (Treg) equilibrium seems to be implicated in T1D and most cases of autoimmunity. Functional analysis in individuals carrying the R620W polymorphism indicate a ""gain of function mutant"" resulting in reduced TCR signaling. However, it is not currently known how PTPN22 is involved in mediating T1D susceptibility: effects on Treg and/or Teff thymic selection and peripheral homeostasis may be responsible. Understanding the mechanisms involved could be a key to our understanding of T1D pathogenesis. In addition, strategies that directly target Teff or Treg by inhibiting signaling from PTPN22 could be successful in halting T1D progression. The goal of this project is to analyze the role of PTPN22 on Treg and Teff equilibrium in (pre)diabetic human individuals and selected mouse models of T1D. The specific aims of this Marie-Curie RIG are: 1. Define the role of PTPN22 (R620W allele) on Treg and Teff cells in healthy versus (pre)diabetic individuals, and 2. Determine the role of PTPN22 signaling on Teff and/or Treg in two well-characterized murine models of T1D, (virally-induced [RIP-LCMV] and spontaneous [NOD]. Objectives to be achieved: 1. Functional
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Testing galaxy formation with gravitational-wave and X-ray observations of massive black holes' (GALFORMBHS) targeting Seventh Framework.

assistant: **Abstract**

I will study the evolution of the masses and spins of massive black holes (MBHs) in competing scenarios for galaxy formation and for the MBH seeds at high redshift, and assess whether they may be discriminated with future gravitational-wave detectors and X-ray missions. This project is extremely timely and relevant for European science because two of the candidates (ATHENA and eLISA/NGO) for the ESA L-class mission selection for the Cosmic Vision program focus on MBHs as gravitational-wave or X-ray sources.The project will build upon some recent work of mine, in which I studied the MBH mass and spin evolution in a state-of-the-art ""standard"" semianalytical galaxy-formation model. To fully exploit ATHENA's and eLISA/NGO's potential, I will extend this work in several directions, namely:1) I will calculate the MBH merger rates for eLISA/NGO, in the ""standard"" galaxy-formation model but with different scenarios for the MBH seeds. I will include the effect of the spins on the gravitational waveforms using a novel effective-one-body model that I previously developed.2) I will consider an ""alternative"" galaxy-formation model that I proposed in 2010 and in which the baryonic evolution is driven by the two-phase structural evolution of the dark-matter halos, and I will work out its predictions for ATHENA and eLISA/NGO and the differences from the ""standard"" scenario.3) I will work out the preditions of both the ""standard"" and ""alternative"" galaxy-formation models for future gravitational-wave detectors in the 0.1-1 Hz frequency band (DECIGO and the Einstein Telescope).4) For both galaxy-formation models, I will analyze how well eLISA/NGO will measure the luminosity distance-redshift relation and therefore dark energy.My unique combination of expertise and the fact t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Fully Optimised Road Maintenance' (FORMAT) under Fifth Framework.

assistant: **Objectives**

The objectives of the project were: to provide better performing road pavement maintenance techniques and procedures that will reduce traffic disruption at road works, thus reducing congestion and improving safety; to develop an integrated cost-benefit analysis model that addresses key aspects of pavement maintenance, including road user costs;  to produce safety strategies for road works for arranging the work site lay-out and the timing of maintenance intervention to maximise the safety of road users and workers; to propose methods, procedures and equipment for monitoring the condition of road pavements at traffic speeds to minimise the number of road closures currently required for acquiring pavement condition data.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Intelligent Pollination for Sustainable Increases in  Crop Yields and Global Food Security' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

iPollinate will bring to market a unique IoT sensor that provides real time monitoring of the foraging rate of honeybeecolonies used for pollination services. This data will be correlated with hive strength and health data using Machine Learning (ML) techniques to provide a precision pollination service enabling farmers to optimise pollination efficiency and crop yields. Our aim is toenable sustainable increases in crop yields of 30%. Our commercial objectives are to build a global business providingpollination intelligence services generating annual sales of over €10million and create 17 high-level jobs in IoT and dataanalytics within 5 years. Actions include:• Advanced design and testing of optoelectronic sensor to collect bee foraging data• Using ML techniques to generate new metrics for pollination effectiveness• Creating a Spatial Decision Support System (SDSS) to support pollination management• Conducting field trials to demonstrate performance• Implementing structured dissemination and exploitation plan to accelerate market adoption.We have an industrial consortium of 3 SMEs with complementary expertise:• IRIDEON (Spain): IoT applications, electronics and software development, prototyping and manufacture• CANETIS (Italy): Development of tools and systems for analysing bee health and behaviour• BEEHERO (Israel): Precision pollination services for farmersThe project will accelerate development and adoption of a disruptive innovation and business model for pollination servicesenabled by unique IoT sensor technology and advanced data analytics. It also addresses priority Societal Challenges,specifically relating to Food Security and Sustainable Agriculture. iPollinate will enable increases in crop yield, quality andnutritional value through more effective pollination
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'REliable, Resilient and secUre IoT for sMart city applications', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

RERUM will develop, evaluate, and trial an architectural framework for dependable, reliable, and secure networks of heterogeneous smart objects supporting innovative Smart City applications. The framework will be based on the concept of security and privacy by design", addressing the most critical factors for the success of Smart City applications.The technical approach aims to enable tighter integration of Internet of Things (IoT) technology in the Smart City domain. The ultimate target is to provide innovative applications that will improve the citizens' quality of life. RERUM will design mechanisms to manage resources in an efficient and effective manner, ensuring confidentiality, authenticity, integrity, and availability of data gathered by IoT objects. The RERUM approach is scenario-independent, hence applicable to the entire gamut of future Smart City applications.<br/>To achieve these goals RERUM will: analyse industrial and Smart City application requirements for steering the overall system design, develop a new, technically innovative framework to interconnect a large number of heterogeneous software and hardware smart objects, using novel approaches, e.g. based on virtualization and cognitive radio, increase the energy efficiency of IoT to provide sustainable infrastructures in the economic and ecologic sense, model the trustworthiness of the IoT and enable secure and reliable exchange of trusted information, enable secure bootstrapping and self-monitoring of networks to detect and mitigate security events, perform proof-of-concept experiments and real-world trials in two Smart City environments to assess the project results with respect to technical feasibility and user acceptance, and assess the portability and its "scenario-agnostic" characteristics