RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'SustainAble Farming for Effective Aquaculture' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Aquaculture is an important food source for the world’s growing population. The increasing demand and productivity of aquaculture leads to global trade in breeding stock, genetic material and aquaculture products for human consumption, but also exacerbates the globalization of pathogens.SAFE-Aqua, an international inter- and multidisciplinary consortium, aims to provide scientific solutions to solve disease-related issues in aquaculture using shrimp as a model through research and innovation staff exchange and sharing of knowledge and ideas from research to market. SAFE-Aqua will explore the benefits of developed feed additives on keeping a healthy gut microbial balance, enhancing immune-capacity, and maintaining nutritional integrity of shrimp as a product. To assess these beneficial effects, SAFE-Aqua will synergize the cutting-edge technology platforms, multidisciplinary and complementary expertise, as well as infrastructure from networks of the partnership among the leading research institutes in France, UK and Thailand and a synthetic biology company in Spain. The outcomes of SAFE-Aqua will undoubtedly help improve competitiveness of EU aquaculture industry whose growth has been relatively constant since year 2000 compared to aquaculture production worldwide. Moreover, we strongly believe that SAFE-Aqua will promote international and inter-sector collaboration through research and innovation staff exchanges and sharing of knowledge and ideas from research to market. The use of cutting-edge innovative technologies will allow to researchers to develop new skill sets helping them to develop their carreers in the best way. In addition administrative staff implicated in the project management will also greatly benefit from the knowledge exchange and build further collab
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Mechanisms of Epigenetic regulation in Development, Evolution and Adaptation' (MEDEA).

assistant: **Concept**

Over the last decade epigenetic gene regulation has become a major focus of scientific research as it was shown to play an important role in normal plant and animal development, but also in the ontogeny of human disease. A role of epigenetic processes in evolution, however, has found little general support to date. The goal of this project is to understand the complex interplay of epigenetic mechanisms in plant development and evolution. Many of the approaches we use rely on the recent advances in sequencing technologies, which allow the analysis of molecular characters at an unprecedented level and speed. To achieve our goal, we will focus on two epigenetic paradigms. In Program A, we will focus on dissecting the mechanisms of genomic imprinting at the MEDEA (MEA) locus in Arabidopsis, which we will investigate using genetic, molecular, and innovative biochemical approaches to gain a comprehensive picture of the complex interplay of various epigenetic pathways. In program B, we will analyze the role of epigenetic change in adaptation and evolution using (i) an experimental selection approach in Arabidopsis, where genome-wide analyses of epigenetic modifications have become possible, and (ii) a stable, heritable, epigenetic change occurring in Mimulus populations. In this system, an epigenetic switch of the pollinator syndrome leads to reproductive isolation and, therefore, has an effect on population structure and thus the evolutionary trajectory. These experimental systems each offer unique opportunities to shed light onto the underlying mechanisms controlling epigenetic states. In combination with the new methodologies used, these analyses promise to provide step change in our understanding of epigenetic processes at the level of genes, organisms, and populations.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Connecting authors and publishers with the world`s best publishing professionals to create high-quality books' under Horizon 2020.

assistant: **Concept**

Reedsy is the world’s only curated self-publishing digital marketplace, connecting authors with the world`s best freelance publishing professionals, who, working together collaboratively, using Reedsy’s well-integrated set of online editing and publishing tools, can create high-quality books, beautifully designed and typeset, and promote them to a wide audience through multiple channels. It is the only digital marketplace from Europe of its kind that can compete with the major global publishing platforms such as Amazon, offering high quality self-publishing at a competitive cost point, and thereby enabling both (i) the growth of Europe’s creative economy in this creative industry pillar and (ii) supporting Europe’s authors and creative minds to find a global audience in a hyper-competitive publishing world.  Reedsy’s innovation excellence was rewarded by awarding them the 2016 The Quantum Publishing Innovation Award, one of Europe’s top innovation awards for the publishing industry.With more than 10,500 authors signed up already, and 750 books created, Reedsy is now planning to expand with the support of the SME Instrument by developing (i) Reedsy for Publishers, a version of their marketplace that will be designed to address publishers’ requirements, as well as (ii) Reedsy Discovery, a powerful suite of pre-publication marketing tools integrated with its already existing and very popular, Book Editor. The company will use the funds to develop and test the functionalities and undertake partnership building efforts with key partners in the publishing ecosystem as a crucial component of its expansion strategy, and based on the recommendation of a patent expert as well as devise and implement its IP strategy to protect its innovation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Chiral Metallopolymers: Synthesis, Self-Assembly and Applications""' (CMSSA).

assistant: **Concept**

The creation of chiral molecules and materials is of major current interest and of key importance to pharmacy, biochemistry, and materials science. Recently, metal-containing polymers (metallopolymers) have emerged as highly promising advanced materials due to their potential uses in various fields. However, the chiral characteristics of metallopolymers are virtually unexplored. We propose to create chiral metallopolymers and chiral self-assembled materials with interesting and important properties. Briefly, the work includes the synthesis of chiral polymeric structures, the induction of helical conformations, and fabrication of chiral self-assembled materials. A variety of novel methods, for instance, using chiral coordinative ligands, grafting with chiral polymeric blocks, templated by DNAs and inorganic chiral materials, and uniform deposition of polymeric helices, will be applied to create chiral metallopolymers with chirality on both/either molecular and/or supramolecular level(s). Applications in asymmetric catalysis, chiral recognition and chromatography, and displays are possible. To achieve these exciting objectives, we propose to send an exceptionally talented student, Huibin Qiu, with key expertise in chiral materials from his Ph.D. work in a top group in China (that of Shunai Che), to the research group of Ian Manners at the University of Bristol, a top group in the field of metallopolymers.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Use of phylogenetics and cell biology to investigate mitochondrial and eukaryote origins' in the context of a Sixth Framework call.

assistant: **Objectives**

Published data indicate that mitochondria originated only once in eukaryote evolution from an endosymbiotic bacterium of still debated evolutionary affiliation.I will be trained in, and use, sophisticated maximum likelihood and Bayesian phylogenetic methods to test the hypothesis that contemporary members of the Ricketsialles, a group of important obligate intracellular bacteria causing major diseases, are the nearest relatives of mitochondria.I will then use the same methods to test whether (or not) eukaryotic genes for non-mitochondrial energy metabolism originated from the mitochondrial endosymbiont, as predicted by competing hypotheses for eukaryote origins. During the transition from endosymbiont to organelle the emerging organelle acquired the ability to import host-nucelar-encoded proteins.I will use classical cell biology and biochemistry to investigate the protein import machinery of highly reduced mitochondrial variants found in parasitic protozoa affecting human health. By doing so, I will illuminate how these organelles function and also provide insight into the minimal requirement for protein import into an organelle. My project will involve a flexible and multidisciplinary approach with training in molecular cell biology and sequence analysis.I will do this work at Newcastle University where there are excellent facilities with Prof. Martin Embley, an expert on mitochondria-derived organelles and phylogenetics. My own expertise in molecular biology and biogenesis of rickettsiae and mitochondria complements that of Prof. Embley, and will ensure a productive and timely synergy.My project is innovative and original and addresses Life Sciences Priority (LSH-2003-1.2.2-3) to provide basic information on the fundamental biology of mitochondria as vital eukaryotic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Multifunctional, adaptive and interactive AI system for Acting in multiple contexts'.

assistant: **Concept**

What if in a near future Artificial Intelligence (AI) becomes human-centric, focusing on human needs and build trustworthiness by mutual understanding? Today, millions of people worldwide suffer from deteriorated motor abilities, due to stroke, brain tumor surgery or accident. This represents a serious society challenge with missing adequate technological response. Patients need assistive devices that are trustworthy, multifunctional, adaptive and interactive, i.e., intelligent, unlike current neuroprosthetics that replace single motor impairments. MAIA proposes a paradigm shift where human-centric AI will control prosthetic and assistive devices. We will investigate and resolve critical steps towards the rapid development of such human-centric control: a radically novel intention decoder, a novel concept for trustworthy human-AI interactions, and a new type of database for acquired information from multiple sources.MAIA AI technology will decode human intentions and communicate the decoded targets to assistive devices and to the users, to ensure compliance and develop trust through natural interaction and mutual learning. The technological outcome will be a multifunctional human-centric AI controller at TRL4 with embedded trustworthy characteristics, suitable to be integrated in robotic arms, wheelchair and exoskeletons.To reach this, MAIA will investigate the principles underlying natural, fast and lean communication and new forms of combinations of neural and behavioural data beyond current data processing. MAIA’s approach will be guided by real needs of end users (patients and caregivers) through their direct involvement in the research program, and by all current knowledge from neuro-, cognitive, and social science research.The application domains of MAIA’s new par
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Free libre and open source software - Worldwide impact study' under Sixth Framework.

assistant: **Concept**

Open source software is arguably one of the best examples of open, collaborative, internationally distributed production and development that exists today, resulting in tremendous interest from around the world, from government, policy, business, academic research and developer communities. FLOSSWorld primarily aims to strengthen Europe's leadership in international research in open source and open standards, and to exploit research and policy complementarities to improve international cooperation, by building a global constituency of policy-makers and researchers.It is expected that FLOSSWorld will enhance Europe's leading role in research in the area of open source and strongly embed Europe in a global network of researchers and policy makers, and the business, higher education and developer communities. FLOSSWorld will enhance the level of global awareness related to open source software development and industry, human capacity building, standards and interoperability and e-government issues in the geographical regions covered by the consortium. The project will result in a stronger, sustainable research community in these regions. Broad constituency-building exercises risk losing momentum after initial workshops and meetings - without specific actions to sustain a focus.FLOSSWorld will perform three global empirical studies of proven relevance to Europe and third countries, which will provide a foundation for FLOSSWorld's regional and international workshops:- Human capacity building: investigating open source communities as informal skills development environments, with economic value for employment generation- Software development: what are the regional and international differences - technical, organisational, business - between open source projects across countr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Beekeeping and biodiversity in europe (BABE)' (BABE) under Fifth Framework.

assistant: **Objectives**

Because honeybees mate in mid air, gene flow occurs between wild and man - kept bees. The propagation of non-native races of bees thus affects the genetics of native bee populations. The cultural differences in beekeeping practice among European countries allow studying how beekeeping affects the diversity of native honeybee populations. Breeding strategies range from replacement of native subspecies with aliens to an absence of breeding and little import of non-native bees. Molecular techniques using both mitochondrial and nuclear DNA markers will quantify the impact of beekeeping on the genetic diversity of native honeybee populations in western Europe. A sustainable breeding concept will be developed that both conserves native biodiversity and permits selection for improved honeybee colony performance (including disease resistance, docile behaviour, and productivity)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Enhancing the Innovation Management Capacity of SMEs (by EEN), Slovenia'.

assistant: **Objectives**

The EC has within its Survey of 2011, carried out on request of DG Enterprise and Industry (DG EI), realized that the main barriers of innovation in the eyes of the SMEs, are lack of financial resources and inability to manage innovation process.Since different understandings of the term ""Innovation Management System"" (IMS) have been noted the EC has supported European Committee for Standardization to provide the stakeholders with a unified definition of relevant parts in the IMS. According to this definition the most important parts of IMS include company's innovation processes from idea generation to innovation result, but also leadership, management skills and other enabling factors, like the ability to cooperate with third parties like RD partners, clients, and suppliers.The objective of this project in Slovenia is to enable SMEs to bridge the knowledge gap in innovation management, get aware of shortages and improve their internal innovation management system and/or focus on achieving market value with their inventions. The consortium will achieve this objectives with providing:1.) Enhancing the Innovation Management Capacity of SMEs. The beneficiaries will receive diagnostic of their innovation system based on the standardized IMP³rove tool. This will lead to the formation of tailored action plan to improve the SME’s capacity to better manage innovation.2.) Key Account Managers – Facilitators for the H2020 SME Instrument. Key Account Managers will identify and source appropriate lead coaches (from predefined pool of coaches), facilitate linking the SMEs to innovation support services and to support the lead coach in delivering services to the SME. The SME Instrument participants will receive the most appropriate services and support to enhance the probability of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Engineered symbionts elucidate gut T cell memory and its (dys)regulation' (2021-2027).

assistant: **Innovation**

A detailed understanding of intestinal T cell memory is crucial for novel treatments against inflammatory bowel disease but also for efficient vaccine design. Th cells induced by the gut microbiota are important for pathogen defence and tolerance, but it is unknown whether they form immunological memory characterised by long-term, antigen-independent maintenance. This has been due to the technical inability of disconnecting T cell induction from bacterial persistence in the gut. The GuT Memory project will yield unique insights into microbiota-directed Th cell memory and its (dys)regulation through uncoupling Th cell induction from luminal persistence of the microbe.Mutant strains of non-pathogenic gut bacteria engineered to transiently colonise germ-free mice will be combined with state-of-the-art adoptive transfer experiments to trace antigen-specific Th cells into the memory phase after their inducing bacterium has been cleared from the gut. With this, I aim to (1) elucidate how the longevity of such responses is regulated by host survival niches versus microbiota-mediated attrition. Uncovering (2) how the sequence of bacterial exposures and their microbial context shape the functional repertoire of such Th cells will demonstrate the impact of lineage flexibility on their protective versus pathogenic potential. (3) Ultimately, successive transient colonisations will provide a novel approach to dissect the physiological relevance of microbiota-specific memory Th cells for the luminal microbe, host protection, and epithelial function. These findings will aid mucosal vaccine design and indicate novel approaches to target pathogenic Th cells in chronic inflammatory disorders.The ground-breaking nature of this proposal lies in the innovation of being able to uncouple micr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'UltraCLEAN thermoforming equipment for ultraclean PACKaging of foods, and in-situ production of aseptic trays.' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

With this CLEANPACK project we, TECSELOR, will put in the market a thermoforming machine that manufactures ultraclean packaging trays, oriented to fresh food products. The machine can be used for aseptic tray manufacturing or for the whole process of food packaging, coupling the adequate module (vacuum, modified atmosphere, etc). Our aim is to reduce the presence of pathogens and spoilage organisms in fresh packed foods, having the biggest impact in foods that are consumed without a cooking step, offering a cost-effective, eco-innovative and energy saving alternative to clean rooms, which are very useful in food industry but expensive to build and maintain.TECSELOR is a Spanish SME founded in 2003 settled in Murcia, dedicated to the design and production of several kinds of food packaging machinery –thermoformers, thermosealers, shrink wrappers vacuum packaging-. Our SME is composed by highly educated personnel, with a vast experience of 12 years in average. We are 37 employees, and our revenue in 2013 (last registered financial data) was €4,250,811.59.The general objective of this project is to bring to the market a thermoforming food packaging machine for in-situ production of aseptic trays oriented to diminishing food borne diseases and food waste, and increasing shelf life in fresh foods products. CLEANPACK will render in the first five commercialisation years an accumulated revenue of €26,800,000 and an accumulated profit of €8,275,000 by selling 67 machines.