RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'The key role of complement mblectin pathway in infectious and chronic disease (COMPLEMENT IN DISEASE)' (1998-2002).

assistant: **Innovation**

Human resistance to microbial infection is mediated by humoral and cellular effector systems. A major part of the humoral immune system is complement which consists of 30-35 proteins that recognize and are of utmost importance for the elimination of viruses, bacteria, fungi and parasites. Diminished complement activity causes humans to become susceptible to repetitive fulminant or severe infections. In the concerted action BMH4-CT96-1005, we analysed the contribution of two pathways of complement in detail and provided evidence that these pathways have essential roles in chronic autoimmune, inflammatory and infectious diseases. More recently a third pathway of complement activation was uncovered. There is a strong suggestion that this pathway is crucial in recognition and clearance of pathogenic microorganisms. It is the purpose of this project to delineate the relative contribution of the MBL pathway in autoimmune and infectious disease.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'In vivo pharmacogenetic investigation of 5-HT mechanisms in emotional learning', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Emotional health and well-being is widely accepted to be crucial for healthy life and the success of societies. Anxiety and depression are two common and debilitating emotional disorders, with highly negative social and financial implications. Serotonin (5-hydroxytryptamine; 5-HT) is thought to be critical to the healthy mood regulation and strongly implicated in the vulnerability to anxiety and depression. Importantly, accumulating evidence suggests that 5-HT’s main influence is upon emotional learning rather than on mood directly. The objective of this proposal is to determine the neural mechanisms through which changes in 5-HT levels, within defined neuronal circuits, affect learning and memory for aversive emotional experiences. New pharmacogenetic techniques will be developed that allow the selective triggering of 5-HT neuron activation and then inhibition in the same animal. We will use this technology to stimulate or inhibit 5-HT release in the basolateral amygdala, a brain area that is crucial for aversive learning, whilst an animal is engaged in an emotional processing task. Through this we will learn how 5-HT modulates neuronal activity in the amygdala at critical time-points during the encoding and retrieval of aversive memories. The results from these studies will provide entirely new insights into how 5-HT modulates amygdala information processing and aversive learning. Understanding how 5-HT affects emotional learning will ultimately lead to a deeper understanding of healthy mood states and the biological mechanisms underlying vulnerability to disorders such as anxiety and depression.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Machine learning based analytics for bacteria cell cycle characterization using super resolution microscopy' (BALTIC) under Horizon 2020.

assistant: **Objectives**

The cellular life cycle, or cell cycle (CC), is the fundamental backbone of the cellular machinery: it orchestrates processes over multiple scales, in space and time. In bacteria, it consists of an internal clock associated with, for instance, cell-size homeostasis at a population level. Although some analytical tools dedicated to characterizing CC are available for eukaryotic cells, such approaches are still lacking when it comes to bacteria cells study.  Moreover, existing eukaryotic cell cyclers are highly limited in terms of both resolution (spatial or temporal) and applications. However, with the rise of antibiotic resistance, there is a real need for reliable quantitative platforms dedicated to bacteria CC and allowing for high throughput comparison studies. This research proposal aims at producing a novel approach for bacteria CC investigation, whilst over-passing the drawbacks associated with existing tools. The developed methodology will rely on cutting edge high throughput super resolution microscopy. We will firstly explore proteins contribution to characterizing CC at the nano-scale, taking a step back from the unreliable and limited size or time dependent estimation. Relying on state of the art machine learning strategies and the identified CC reporting features, I will develop tactics to circumvent the trade-off between temporal and spatial resolution constraining fluorescence nanoscopy when it comes to the study of dynamic processes such as CC. I will implement a methodology to extract, for the first time, dynamic models of bacteria CC from fixed cells super resolved images. It is a considerable step forward: enabling to benefit from a spatial resolution around 10 nm, whilst inferring live-cell akin quantitative information. The highly innovative approach
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'PEATland modelling for global carbon cycle and climate models' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Prediction of future climate change can only be achieved through models of the global climate system and its interactions with earth system processes. The reliability of the predictions depends on building the best understanding of these processes. Changes in the global carbon cycle are a source of major uncertainty in models and terrestrial carbon stored in peatlands is a critical element of this. The action proposed here will bring state-of-the-art process modelling into global vegetation models that are used in projections of future climate change. An improved understanding of peatland dynamics and functions will also have implications for management and climate mitigation strategies for wetlands, agriculture, land-use, and energy. I have worked extensively in North America on one of the most sophisticated peatland process models. I will work with Dan Charman and Angela Gallego-Sala at Exeter to build this model in to one of the most widely used dynamic global vegetation models so that peatlands and their carbon balance are better represented within global climate models. The work will thus allow quantification of the impact of peatlands on the global carbon cycle in the past and in the future. The action will bring top level expertise in peatland modelling back to Europe and build a bridge between the North American peatland modelling community and those in Europe. It will expose me to training and development in the necessary skills, people and laboratories to take this work forward independently in a European institution in the future. The supervisors at Exeter will develop their already strong record in carbon cycle and climate modelling and further develop links with other European workers and key groups in North America. Overall the action will provide a secure
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'European Data as a PRoduct Value Ecosystems for Resilient Factory 4.0 Product and ProDuction ContinuitY and Sustainability' in the context of a Horizon Europe call.

assistant: **Objectives**

As part of the green, circular and digital transformation of the European manufacturing community, it is extremely important that data-driven digital manufacturing processes urgently incorporate innovative and active resiliency strategies at production and supply chain levels to maintain their sovereignty and competitiveness levels, respecting European digital values (excellence, privacy, trust) to improve individual and value chain flexibility. In order to achieve long-term resilience to reorganise supply chains or speed up decision making to dealt with any disruption, it is imperative to ensure the implementation of distributed data-intensive intelligent and dynamic industrial decision support, augmentation and automation processes, integrating Artificial Intelligence (smart anticipation) and Intelligent Automation (rapid response) capabilities in Human-Automation symbiosis. Hence, only businesses that can articulate their data, based on AI, digital thread and digital twin solutions, will be able to react rapidly to external shocks.RE4DY mission is to demonstrate that the European industry can jointly build unique data-driven digital value networks 4.0 to sustain competitive advantages through digital continuity and sovereign data spaces across all phases of product and process lifecycle, proposing ?Data as a Product? core concept to facilitate the implementation of digital continuity across digital threads, data spaces, digital twin workflows and AI/ML/Data pipelines. This concept leverages resiliency on top of advanced manufacturing digital processes and value ecosystems supporting the development and implementation of digital continuity, so distributed data management solutions implemented to deal with factory resiliency can be immediately and seamlessly reused to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Tracing memory formation in a behaving animal: analysis of learning-induced morpho-functional plasticity along the bee’s olfactory system'.

assistant: **Concept**

Memory formation and extinction are fascinating aspects of brain functions. Observation of ex vivo and in vitro experiments provided a framework for understanding associative memory-related plasticity. However, memories are generated via local neuronal interactions within the context of their global networks, and understanding their formation requires in vivo studies in naturalistic conditions, which remain technically challenging. Here, I will use a functional calcium imaging approach to investigate memory formation and extinction in behaving honeybees. I will adopt the honeybee as a model system because of the accumulated knowledge on associative learning, the availability of a behavioural read-out for both appetitive and aversive memory formation, and its robustness, which allows for long-lasting imaging experiments. I will focus on its olfactory system because of the optical accessibility, and its analogy with the vertebrate one. Previous works have established the methods for honeybee brain imaging analysis in vivo during appetitive and aversive conditioning. Within this project, I will perform long-term imaging experiments in behaving animals, while monitoring the process of short and long-term memory formation and extinction in the three main neuropils of the olfactory system: the antennal lobe (the primary odour processing centre), the mushroom bodies (possibly dedicated to odour recognition), and the lateral horn (involved in odour valence evaluation). My specific goals are (1) characterizing the morphological and functional changes induced by associative learning throughout these neuropils, (2) highlighting the functional dynamics of a stimulus representation during short and long-term memory formation and extinction, and (3) comparing the memory engram of pos
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Just Central Banking'.

assistant: **Objectives**

The recent financial crisis, and the ongoing ecological crisis, call for an urgent examination of the central banks’ place in society, both as a cause of harm and as a potential agent of justice. The central aim of this project is to determine what role central banks can play in the transition towards a more just and sustainable economy.First, this project will attempt to uncover what, if anything, is wrong with current central banking practices. The financial ethics literature is divided on whether their core problem is their lack of legitimacy, or their negative effects on justice and environmental sustainability. The first part of the project aims to show that all these problems stem from the unfair and inefficient division of political and epistemic labor between states, central banks, and commercial banks.Second, this project will delineate and defend potential reforms, which are able to improve the fairness and sustainability of central bank’s practices. The project will focus on new monetary policy instruments that central banks could use to target firms, banks, and citizens more directly. It will investigate how these policy tools can achieve a fairer balance of power between central banks, states, and commercial banks.In sum, by producing a unified theory that is able to account for the diversity of harms and benefits of central banking, this project aims to provide guidance on the ethical role of central banks and the necessary reforms of central banking.


**Keywords:** Central Banks, Economic Ethics, Financial Ethics, Theories of Justice, Theories of Legitimacy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Development of a new antigraffiti system, based on traditional concepts, preventing damage of architectural heritage materials' (GRAFFITAGE) under Sixth Framework.

assistant: **Objectives**

Graffiti is a major, increasing danger to architectural heritage materials, generating also a negative social connotation. Apart from aesthetics aspects, interactions of graffiti with substrate, as well as cleaning procedures, threaten historical substance . Monuments made of stone, bricks and mortars are menaced by this problem because very often, porous natural materials were employed. Two major kind of coatings are currently being used for protecting surfaces against graffiti: permanent and sacrificial. First kind is suited for materials with low porosity, as metals and concrete, but does not fit the requirements for porous ancient materials. Second one is sometimes used in monuments, but it is not an appropriated solution, since removal procedures can da mage substrates somewhat. Hence, effective solutions for anti-graffiti systems is an urgent social and technical necessity. The main objective of this project is to develop novel conservation coatings suited for protecting materials of historical monuments , based on a similar structure of ancient protein coatings, avoiding the disadvantages of currently used antigraffiti coatings . This develop is based in a totally new formulation made by complexation of polyampholytes with polymeric amines modified by flu orocarbon residues. These will be a new generation of antigraffiti coatings, specifically suited for the protection of monuments, which after further development, could be commercialised and applied by SME's involved in this market, thus increasing the com petitiveness of these companies. Main characteristics of these products are: Low surface energy Permanent under out-door conditions Reversible to specially designed mild cleaning systems Permeable to water-vapour Impermeable to liquid water Transparent The obj
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Decision support system for water management in the Mediterranean region' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

The consortium intends to research and develop a prototype management decision support tool based on System Dynamics models for short and intermediate (up to three years) planning horizons for the effective use of available water resources within an integrated resource and supply network. To achieve this broad aim the following objectives are defined :* To carry out an investigation into the statistical modelling of rainfall catchment in order to quantify over a given geographic region and time scale the rainfall variation typical of the region.* Development of a high resolution System Dynamics Model of the water supply and distribution network to support management decision making.* To extend the Systems Dynamics model to function within an integrated resource management system and to add a GUI to produce a working end user prototype.The study areas of the project are the islands of Cyprus and Malta.Expected Outcome* Two working System Dynamics models which can be used by water company personnel in Cyprus and Malta as a decision support aid for planning water resource utilisation.* A comprehensive statistical rainfall model which can be used either in conjunction with the System Dynamics models or independently as a long term planning aid for developing improved water catchment strategies in semi arid regions.The key activities include :* Exploring the detailed spatial and temporal aspects of rainfall catchment. This work will incorporate a variation of the maximum likelihood method and adapt the latest developments on using the Data Based Mechanistic (DBM) approach to the modelling of non linear environmental systems It is also necessary to develop a specific statistical theory of errors for the distribution models developed. It is proposed to use detailed data from e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Holographic applications of supergravity' (APPSG).

assistant: **Concept**

In this project we will develop supergravity tools to study the strong coupled sectors of High Energy and Condensed Matter systems using the gauge gravity duality. We will first find, via consistent truncation, new large classes of lower-dimensional supergravity models that admit an exact string theory embedding, and will fully characterise and classify them. We will use these theories to propose, on the one hand, novel models of holographic superconductors and quantum critical points, and draw concrete string theory predictions about their properties. We will also use these model to pursue an all-time novel, holographic description of (quantum) turbulence.  On the other hand, we will build supergravity models dual to large classes of field theories displaying phenomenologically realistic features like confinement and chiral symmetry breaking, thus considerably expanding the currently available string-derived QCD-like models.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'The international dimensions of authoritarian regime survival: comparing “dictaplomatic” strategies in post-Soviet Eurasia'.

assistant: **Innovation**

DICTAPLOMACY investigates an understudied dimension of authoritarianism – the use autocrats make of diplomacy as a tool of regime-survival. The project analyses and compares the foreign policy strategies and “dictaplomatic” tactics of four ideal-typical authoritarian regimes in post-Soviet Eurasia, with the aim of modelling the mechanisms whereby diplomacy serves them for external regime-legitimation and authoritarian consolidation. DICTAPLOMACY is a multidisciplinary project that combines insights and methods from comparative politics, international relations (IR) theories and foreign policy-making analysis. It elaborates an innovative framework for analysing rogue behaviour in contemporary IR. It departs from the idea that the EU’s democracy-promotion efforts in Eastern Europe require a better understanding of the foreign policy manoeuvres of post-Soviet authoritarian regimes. In identifying the international components of authoritarian resilience, DICTAPLOMACY also highlights which incentives and coercive means could limit the resilience and contain the diffusion of authoritarian governance. This is a timely endeavour, given the growing assertiveness of Russia in world affairs, and the emerging “nuisance” capacity of many of its undemocratic neighbours (Belarus, Azerbaijan and Kazakhstan notably) in regional affairs. Building on the researcher’s expertise in post-Soviet transition and the geopolitics of Eurasia, as well as on the leading academic experience of the host institution in diplomatic studies, the Individual Fellowship will provide the experienced researcher with a chance to acquire new skills, thus reinforcing her maturity as an IR scholar, as well as the host institution’s own visibility in the European Research Area. DICTAPLOMACY is a policy-relevant pro