RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Research in Europe and Diversity Inclusion'.

assistant: **Objectives**

The public-private partnership, READI, seeks to help clinical studies (CS) to finally serve the complete general population, and therefore more patients. To date CS have struggled to recruit and retain participants from diverse backgrounds and communities, such as marginalized or disadvantaged groups (e.g., sexual, gender, age, cultural, and socioeconomic cohorts). The resulting knowledge gaps entrench or increase health disparities. The READI consortium strives to tackle these challenges by fostering a more cohesive and integrated CS ecosystem for underserved (US) and underrepresented (UR) communities. It will actively connect all key stakeholders who can facilitate access to a wide range of patient populations. It will provide these stakeholders with the necessary tools, training programs, and approaches essential for the recruitment and retention of US/UR patients in CS.In addition, it will design, build and implement a digital platform which is patient-centred, sustainable, open and innovative. This will foster improved access to CS information and READI tools, while also supporting patient connections with the created communities. Finally, at least 4 CS will be used for testing the effectiveness of the developed tools and approaches. READI has a three-fold objective: to help US/UR communities overcome CS participation barriers (e.g., lack of information/awareness, mistrust, poor communication, geographic limitations, prejudice), which in turn will improve research of many diseases and conditions, preventative care and treatment effectiveness in different demographic groups, and better serve society. READI’s success will draw from its interdisciplinary, multi-stakeholder, consortium composition of 73 organizations from 18 countries, with key expertise in drug develo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Towards identification of the unifying principles of vertebrate adaptive immunity' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

About 500 million years ago, the two sister groups of vertebrates independently evolved alternative forms of adaptive immunity, representing a striking example of convergent evolution. Whereas the components and functions of the immune system in jawed vertebrates (ranging from sharks to humans) are well characterized, much remains to be learned about adaptive immunity in jawless vertebrates (lampreys and hagfishes). Up to now, progress in understanding immunity in jawless fishes was hampered by their complex life-cycle, long generation time, and the difficulty of raising fish in the laboratory for extended periods, particularly after in vitro fertilization. Based on our recent methodological advances in aquatic husbandry and successful CRISPR/Cas9-mediated genetic modification, we propose to conduct a large-scale analysis of cellular immunity in lampreys laying the foundations for the identification of the unifying principles of vertebrate immunity. Our experiments will address the development and characteristics of different T cell subsets, the molecular basis of antigen receptor assembly, and the function of the two principal T cell lineages during the immune response. We will also examine the structure and function of the stromal microenvironment in the lamprey thymus equivalent, which is considered to be the site of T cell development. A particular focus will be on the functional analysis of a recently discovered MHC-like locus in the context of T cell development, and in the essential self/nonself discrimination mechanism(s) at play during the immune response. We expect that the identification of common design principles of adaptive immunity in vertebrates will provide us with an unprecedented view on immune functions in humans, potentially guiding the development
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Education for Standardisation in the EU'.

assistant: **Concept**

Standards significantly impact EU’s GDP, its competitiveness in global markets, but also the promotion of the Single Market and are key instruments for disseminating its core values and supporting its New Industrial Strategy and Green Deal. Likewise, they are essential for efficiently developing the digital, data-driven and, and green economy, and supporting the EU’s interests in global markets and are perceived as important future tools for disseminating its core values. Nevertheless, EU stakeholders do not fully exploit the opportunities of standardisation. The number of the EU’s standardisation experts is insufficient, in particular in international committees; a pool of young professionals from the EU entering standardisation are missing is needed. Standardisation education canaddress these challenges, but is underdeveloped and fragmented at all EU education levels.Edu4Standards.eu addresses this by specifying standardization skills needed in the EU, analyzing the fragmented teaching landscape and its gaps, and developing an Innovative Teaching Concept on Standardardisation (ITCoS) suitable for various study contexts and specifically considering digital, green, and social aspects. Edu4Standards.eu involves all levels from BSc to professional education and all key stakeholders, represented by 11 HEIs from 9 countries, CEN incl. 27 national NSBs, 1 RTO, 3 SMEs, and extensive stakeholder networks with >300 organisations and an External Advisory Group with all international standardization bodies and industry representatives. Main outputs: ITCoS, 5 pilots with robust and efficient direct and distant standards teaching modules, 15 EU Academic Standardisation Days, a Students’ Standardisation Association, a CEN Workshop Agreement and a EU Roadmap for Standardisation on Ed
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Innovative diagnostic device for the early detection of diabetic neuropathy in diabetes patients' in the context of a Horizon 2020 call.

assistant: **Objectives**

The objective of the innovation project is to develop and clinically validate the first diagnostic device for the early detection of diabetic neuropathy (also referred to as diabetic foot). Diabetic foot is a common complication of both type 1 and type 2 diabetes. Current methods are only able to detect diabetic foot once the patient is already experiencing loss of sensation. This can result in an increased number of amputations and costs as a result of those amputations. The disruptiveness and the market potential of the new device lie in its capacity to identify diabetic neuropathy at a very early stage. The device will fill the identified niche on the market and contribute to better clinical outcomes for the patients. The main need of the users (physicians, nurses, policy makes, and patients) is access to an efficient dependable method for early detection of diabetic neuropathy.  These needs will be met through the prototype device allowing physicians and nurses to assess the condition and determine appropriate treatment.  The Phase 1 project will develop a strategic business plan for the commercialisation of the innovative diagnostic device for the early detection of diabetic neuropathy. The project will strengthen VibroSense’s understanding of the European market in general and verify the economic viability of the clinical validation to be pursued within the Phase 2 project.  The late diagnosis of diabetic foot results in patient’s suffering and substantial health-care costs. It is estimated that approximately 1/9 of the total healthcare expenditures in Europe is spent on diabetes, with foot care being one of the more dominant costs. The project addresses this EU-wide challenge by proposing a new early-diagnostic method. The new device will build a strong case for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Fully Coupled Fluid-Solid Simulation of Upward Flame Spread and Fire Growth' in the context of a Seventh Framework call.

assistant: **Objectives**

The proposed project will encompass a multitude of modelling and simulation techniques, that complement each other, bringing together fluid simulation, conjugate heat transfer, material flammability, pyrolysis, combustion, materials property and  analytical methods spanning across a variety of disciplines in order to exploit the Fellow’s expertise in computational fluid dynamics (CFD), combustion, chemistry and numerical analysis to a basic and yet very important engineering problem that underpins the fire safety in the built environment and transport systems. The Fellow will integrate the different modelling techniques to capture the complex physics and chemistry that underpins the complex processes of flame spread and fire growth. He will also make full use of his analytical ability to critically assess the experimental data which is abundant in quantity but presenting conflicting results, in some cases; and on this basis, select appropriate data for model validation. He will also conduct new experiments in the host’s partner institution to facilitate blind validation. The Fellow will thus deliver a validated flame spread model within the frame of the open source CFD code OpenFOAM, that will be able to predict upward flame spread in different geometric configurations and complexities. He will also demonstrate the use of the powerful-state of the art predictive tool to attack flame spread in realistic fire scenarios, such as warehouse fires and fires in aircraft. The Fellow, through regular seminars, workshops and other dissemination activities, planned for the duration of this project, will also transfer knowledge directly to the European academic and engineering community as well as the industry community that is charged with the responsibility of fire safety for Eur
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Beyond Boycott: Musical Internationalism and the Making of Race in Apartheid South Africa' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

This project proposes to investigate the relationship between Western art music, cultural boycott, and the making of race in apartheid South Africa. In recent years people around the world have been encouraged to participate in political activism by the Palestinian Boycott, Divestment, and Sanctions (BDS) movement, #BlackLivesMatter, #MeToo, #RhodesMustFall, and numerous fossil fuel divestment campaigns. Artists and musicians, too, have contributed to these movements both as activists and through their work. But in a world where the arts are often celebrated for their capacity to promote peaceful dialogue, the confrontational nature of protest movements has prompted artists, scholars, and activists to ask, How do cultural exchange and political activism intersect? Beyond Boycott addresses this question from a historical perspective by turning to one of the most important precursors of current boycott movements: the global cultural boycott of apartheid South Africa (c.1954-1991). The proposed project develops a social and cultural history of the South African boycott, focusing especially on the hidden histories of Western art music performerscommonly described as classical musicianswho defied sanctions to perform in the country. Through archival research, the project maps the extent of classical musicians breaking of the boycott, before asking how these performers interacted with the anti-apartheid movement, and how their appearances in South Africa contributed to a racial classification system that viewed culture as a marker of race. The main research objectives are to trace the extent of musical activity by international performers in defiance of the boycott, and to investigate the apartheid government's use of these performances to develop racial classifications and t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Radiometer based on nonlinear microwave to optical conversion in a resonator.'.

assistant: **Objectives**

The ATESCA (Ambient Temperature Extremely Sensitive Radiometer for CubeSat Applications) project seeks to advance radiometer technology by achieving highly sensitive microwave detection for space-based applications, such as radio astronomy and Earth observation, without the need for cryogenic cooling of the detector. This project is particularly focused on improving the detection of microwave radiation from the ozone of earths atmosphere and from the cosmic microwave background (CMB).ATESCA radiometers utilize a nonlinear optical upconversion process to transfer weak microwave signals into the optical domain. This process is intrinsically noiseless, and it has been shown theoretically that a good signal to noise ratio can be achieved even when the whole setup is sitting at room temperature (opposed to direct detection of the microwave radiation).The nonlinear upconversion process is intrinsically weak. Hence the team plans to employ whispering gallery mode resonators, which support resonances in both optical and microwave domains to significantly improve conversion efficiency. It has been shown theoretically that with the planned implementation, a photon conversion efficiency from the microwave (> 100GHz) to the optical domain of 1% can be achieved. This will enable the proposed radiometer with high sensitivity but would also be interesting for future quantum technology.This is a planned collaboration between a group in Madrid, Spain (UC3M) and Dunedin, New Zealand (UoO). The researcher will demonstrate the proposed conversion efficiency and hence sensitivity on a benchtop experiment and, afterwards, will implement the system into two actual payloads for CubeSat missions to demonstrate the radiometer.


**Keywords:** optical resonator, whispering gallery mode resonator
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Biocompatible surfaces to minimise medical device associated infections' (ADHESTOP).

assistant: **Innovation**

Catheter-associated infections are a major problem in modern medicine and one of the most common causes of death in the treatment of seriously ill patients. The proposed project is focused to the prevention of bacterial colonization on peritoneal dialysis catheters by a biomimetic monomolecular coating consisting of tetraetherlipid (TEL) molecules. The TEL molecules will be immobilised covalently resulting in a dense and stable membrane-like barrier against bacterial adhesion and biofilm formation. Due to the fact that bacterial adherence is controlled thermodynamically the outermost hydrophilic headgroup of the TEL will be modified to obtain a positive enthalpy of adhesion and to allow surface-coupling of antimicrobial agents. Thus anti-adhesive and an anti-microbial catheter surfaces can be designed to prevent bacterial adhesion as the main prerequisite for medical device related infections.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on '3D structure of the long non-coding RNA Xist by complementary cryo-electron tomography and single particle cryo-electron microscopy'.

assistant: **Innovation**

Recent studies have highlighted a pivotal role for long non-coding RNAs (lncRNAs) in normal physiology and disease. As a key example, Xist lncRNA is crucial during the early development of female mammals and is involved in many diseases, e.g. progeria and cancers. To date, cellular and developmental studies have advanced our knowledge of the function of Xist, but a detailed understanding of molecular mechanism is lacking.Therefore, the overarching aim of my proposed research is to directly visualise Xist RNA/ ribonucleoprotein particles (RNPs) in cryo cells at sub-atomic resolution. To this end, I have formulated the following objectives: 1) preparing a cryo sample of mES cells expressing Xist RNA optimised for cryo electron tomography (ET); 2) visualising 3D-Xist RNPs in the mES cell; 3) generating homogenous pseudo-physiological Xist RNPs for single particle cryo-EM; 4) Solving the 3D sub-atomic resolution structure of Xist RNP; 5) Analysing a composite cryo-EM/-ET structure of the Xist RNPs in the mES cell.To achieve this aim, I will employ an interdisciplinary approach including cutting-edge cryo-structural techniques and elegant mES cell biology. My supervisor Prof Brockdorff is a leading scientist in Xist lncRNA research and the host has a state-of-the-art cryo EM facility. The University of Oxford is a world-class research centre, providing excellent transferrable skills trainings and a fantastic infrastructure for career development.The first high-resolution 3D structure of a lncRNA resulting from this innovative research will benefit not only the lncRNA research field, by providing novel molecular insight of the Xist lncRNA, but also the structural biology field, by expanding the 3D RNA structural potential. Dissemination and exploitation of this work, to be ac
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Photovoltaic fuel-cell hybrid system for electricity and heat production for remote sites ('PVFC-SYS')' (PVFC-SYS) targeting Fifth Framework.

assistant: **Abstract**

Objectives and problems to be solved: Many remote sites exist and depend on stand-alone power system. A photovoltaic field, an electrolyser, a fuel cell and gas storage systems constitute the system under study. The primary source is the sun (and water), the produced energy is electricity and heat and the system is intended to be a future competitor of hybrid PV / Diesel systems, both from an environmental point of view (low noise and zero emission) as from an operational cost point of view. The main objective of the project is to demonstrate the feasibility of this system, based on the renewable energy. The investigations will allow to determine the optimal size and design of the components, the best adapted fuel and feeding process and the best way to manage the energy streams. The system has to be performing, reliable, easy to handle and safely constructed. The development of simulation tools will help to chose the design and the management, at first, of the pilot systems and in term, of each power system to be built in a remote site. Description of the work: The PVFC-SYS project is composed of the following work activities:· System design, test and construction· System assessment· Operation cost and market analysis· Simulation and tool design· Safety analysis Two stand-alone power systems will be constructed: The first, a test plant, will be built in the south of France. This test bench, a 3 kWp photovoltaic system equipped with a 5 kW fuel cell and a 3 kW electrolyser, will be used to compare different configurations and operating strategies and to assist the development of the simulation tools. Then, the second pilot system of nearly the same size will be installed in an industrial company interested in exploring new environmentally friendly technical solutions. T