RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Crystallization of charged proteins' (PROTEIN-CRYSTALS).

assistant: **Innovation**

Protein crystallization is a very active field of current scientific interest, but also heavily used in biotechnological processes. Protein crystals are for example necessary to elucidate the structure of proteins by means of spectroscopic methods. The knowledge of protein structure will boost the development of new biotechnological materials and drugs.However, currently, the number of proteins that can be crystallized is very small, and the conditions under which crystallization occurs are unpredictable. To achieve European leadership in biotechnology, it is crucial to improve the methods used in protein crystallization, which requires knowledge of the physical mechanisms behind it. Crystallization can be described by classical nucleation theory.This requires information on the surface energies, which cannot be obtained through experiments. Analytic estimates based on mean-field approaches exist, but many crystallization precipitants are multivalent salts, which these theories fail to describe. We therefore propose to study protein nucleation directly by computer simulations.We will develop the necessary simulation methods by employing recently developed Monte Carlo methods, such as the sampling of rejected states. For MC algorithmic development, the work group of Professor Frenkel is world leading. In addition, the AMOLF has a strong biophysics group. Therefore the applicant will receive excellent training in MC techniques and broaden his scientific background to include biophysics.In addition, the project will strengthen his communicative skills by exposure to an interdisciplinary Dutch research group. This will allow the applicant to start a career as an independent junior researcher. As a long-term effect, the project will create permanent intra-European research l
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'INNOVATIVE PILOT LINES FOR SUSTAINABLE GRAPHENE-BASED FLEXIBLE AND STRUCTURAL ENERGY HARVESTING AND STORAGE DEVICES' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

GRAPHERGIA aims is to develop a new science-based, holistic approach, implementing new advances to achieve one-step, laser-assisted synthesis, processing, functionalization and simultaneous integration of graphene-based materials and graphene nanohybrids, directly into relevant energy harvesting/storage devices. This will lead to a scalable, cost-effective and climate-neutral production of (i) e-textiles with the specific functions of wearable power supplying and self-powered structural sensors and (ii) next generation electrodes for Li-ion batteries. Based on current TRL 3-4 activities, the consortium explores novel ideas for 2D materials engineering and integration at TRL 5 or higher, establishing versatile pilot-scale-based approaches for these two types of applications. Configurations of TENG-based e-textiles will be prepared to fabricate flexible architectures, designed to sustainably convert energy from the environment to electricity. Laser-scribed solid-state micro-flexible supercapacitors, will be coupled to TENGs, via innovative power management circuits, acting as energy reservoirs to provide on-demand batteryless charging to wearable devices and sensors. All-in-one, self-charging power textiles with integrated electronic systems will provide a human-body-centric technology and interface of the user to the IoT by wireless transmission of sensors’ signals. In parallel, GRAPHERGIA defines a credible “dry electrode” approach to fabricate next generation electrodes for Li-ion batteries aspiring to reach the technical/economic targets of the 2030 European SET-plan. The proposed methodology will be implemented by blending recently devised IPR-protected technologies of consortium partners. To achieve these targets, a combined 2D materials and process-oriented approac
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Scrap tyre rubber to combat traffic vibrations' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

Europe currently scraps more than 300 million tyres annually, and this is set to increase in line with the rapid increase in the use of motor vehicles. Although grinding rubber is a well-known technology and readily available, the number of commercial applications for this rubber granulate is by far not sufficient to deal with the rubber waste. This project is proposed to investigate the application of rubber granulate as a vibration reduction embankment in road and railroad applications. The challenging idea is that the rubber particles will reduce traffic vibrations and associated noise. Hence, this project promises to kill two birds with one stone it effectively creates a new application for scrap tyre rubber and it will help to reduce vibrations and noise caused by road and railroad traffic.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Active Optical Phase-Change Plasmonic Transdimensional Systems Enabling Femtojoule and Femtosecond Extreme Broadband Adaptive Reconfigurable Devices' in the context of a Horizon 2020 call.

assistant: **Objectives**

PHEMTRONICS has the ambitious vision of translating forefront knowledge in phase-transformation dynamics of “light controllable active matter with reconfigurable and interactively tunable dynamical properties” into broadband reconfigurable and adaptive devices by developing a radically novel transdimensional materials platform that is intrinsically phase change, low-loss plasmonic and electronically topological. The photon-electron-phonon coupling will enable a new technology paradigm of adaptive optical signal processing with key metrics of the “femtosecond-scale switching time”, “ultralow power of femtojoule/bit” and “microwave-to-optical frequencies” broadband capability required for reliable multibit operationsTo do so PHEMTRONICS will (i) develop a novel platform of eco-sustainable non-toxic phase-change transdimensional materials with a large pool of structural motifs, accessible close to room temperature; (ii) pioneer a programmable mixed-mode plasmon-opto-electrical machine, actuated with novel active phase-change low-loss plasmonic nanoantennas, exploiting mechanisms of dynamical amplification of phonons by plasmons to achieve mode-selective enhancement (iii) master beyond-equilibrium phase-transformations through predictive models to guide reconfigurability of devicesWe will deliver innovative ultrafast light induced phase-change switches, dynamically reconfigurable nanoantennas and adaptive switchable multiple-band detectors surpassing the current paradigms of speed, energy and frequenciesPHEMTRONICS interdisciplinary team covering the whole value chain, from a novel class of plasmonic phase-change materials, to fabrication, design, modelling tools and integration to new device architectures, will herald a new era in the fields of mobile communications, optic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'A SECURE HEALTHCARE ENVIRONMENT FOR INFORMATICS RESILIENCE'.

assistant: **Objectives**

The health sector is steadily becoming the de facto target for cyberattacks. Based on the most recent ENISA report at the end of 2018, cybersecurity incidents have shown that the healthcare sector is one of the most vulnerable. Focusing specifically on Electronic Medical Devices (EMD), they suffer from numerous and multi-layered vulnerabilities . Default, weak or no password authentication for remote connections, unencrypted traffic or obsolete and insecure cryptographic algorithms, unsupported operating systems, outdated, unmanaged and vulnerable software are among the most serious problems that jeopardise both their smooth operation and the data aggregated and stored. The vision of HEIR is to provide a thorough threat identification and cybersecurity knowledge base system addressing both local (in the hospital / medical centre) and global (including different stakeholders) levels, that comprises the following pillars: (i) Real time threat hunting services, facilitated by advanced machine learning technologies, supporting the identification of the most common threats in electronic medical systems based on widely accepted methodologies such as the OWASP Top 10 Security Risks and the ENISA Top 15 Threats; (ii) Sensitive data trustworthiness sharing facilitated by the HEIR privacy aware framework; (iii) Innovative Benchmarking based on the calculation of the Risk Assessment of Medical Applications (RAMA) score, that will measure the security status of every medical device and provide thorough vulnerability assessment of hospitals and medical centres; (iv) The delivery of an Observatory for the Security of Electronic Medical Devices; an intelligent knowledge base accessible by different stakeholders, providing advanced visualisations for each threat identified in RAMA and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Turning climate-related information into added value for traditional MEDiterranean Grape, OLive and Durum wheat food systems' (MED-GOLD) targeting Horizon 2020.

assistant: **Abstract**

MED-GOLD will demonstrate the proof-of-concept for climate services in the agriculture sector by developing case studies for three hallmarks of the Mediterranean food system: grapes, olives and durum wheat.  Agriculture is primarily climate-driven and hence highly vulnerable to climate variability and change. Evidence suggests that the Mediterranean region is under immediate threat of shifting climate patterns and the associated ecological, economic and social effects. Developing a capacity to turn the increasingly big climate-related data into tailored climate services that can inform decision-making in agriculture, is therefore a priority both in Europe and worldwide. The long-term goal of this project is to make European agriculture and food systems more competitive, resilient, and efficient in the face of climate change, by using climate services to minimize climate-driven risks/costs and seize opportunities for added-value.The MED-GOLD project aims to develop climate services for olive, grape, and durum wheat crop systems that are the basis for producing olive oil, wine and pasta. This set of crops and related food products is of utmost climatic, ecological, economic, and cultural relevance to the Mediterranean region. Because olive oil, wine and pasta are not only hallmarks of the Mediterranean diet  but also food commodities with a global market, there is considerable potential for developing climate services with high added-value for olive, grape, and durum wheat. A key challenge is to co-design prototype pilot service applications involving both suppliers and users in the three major traditional Mediterranean crop systems so as to demonstrate the added-value of data/information-driven responses to changes in the climate system. The operational decision-making o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Digital Intelligent MOdular FACtories'.

assistant: **Objectives**

The digitalization of industry opens the path for mass customization but requires leveraging the existing manufacturing ecosystems and establishing a collaborative manufacturing environment. DIMOFAC project will enable the modularity, adaptability and responsiveness of a production line by the integration of Plug-and-Produce modules in a Closed-Loop Lifecycle Management System, for continuous production adaptation, optimization and improvement, in a fast and flexible manner. Reconfigurability is achieved by implementing a Digital Twin of each module and by deploying Digital Thread linking product and process dataflow, enabling seamless secure communication throughout the product lifecycle in factory and connecting it to the management systems in conformance to RAMI4.0.The DIMOFAC consortium is issued from the leading European open initiatives on smart manufacturing, leveraging know-how from past and running EU projects such as INTEGRADDE, COMMUNION, HIMALAIA, BRAINPORT, iMAM, MIDIH, MARKET 4.0 and building upon a pre-existing network of open DIHs and competence centers such as SMART FACTORY KL, PICTIC, FFLOR, AFH, MANUHUB@WG. Partners will further extend their services and networks to leverage on the increased flexibility brought by modular production systems. Six industrial pilot lines, with multi-material manufacturing, additive manufacturing and assembly capabilities, will enable to demonstrate DIMOFAC Modular Factory Solution, with reconfiguration time reduction of production lines, up to 75% expected for interactive displays (SCHALTAG), 50% for cosmetic, aeronautic and additive manufacturing (ALBEA, EIRE COMPOSITES and SCULPTEO); 30% for shavers (PHILIPS) and industrial modules (VDL). A key result will be the network of open pilot lines, offering R&T and services s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'European Network of Research Infrastructures for providing Access and Technological Advancements in bio-NMR' (EU-NMR) targeting Sixth Framework.

assistant: **Abstract**

EU-NMR aims at providing an integrated approach to supporting fundamental research in the life sciences by mobilising the unique tools and expertise available at five Research infrastructures for bio-NMR. The five RI compromise a high quality research environment for European researchers. The partners in EU-NMR strive to expand the application envelope for bio-NMR techniques. To realise the aims, the awareness of researchers should be raised in the life sciences for the benefits that bio-NMR can generate in their research. In addition, there should be collaboration between the infrastructures for bio-NMR operating at the local, regional, national or European level to establish an efficient and cost-effective service network for bio-NMR, an asset for the ERA, and an extended user base in the research community.In order to establish NMR as an important tool for functional analysis of biological pathways and to integrate the services available, the following tightly linked activities will be executed:1. Network the RIs for bio-NMR operating at the local, regional, national or European level into an integrated structure with transparent access and mutual referral of users;2. Provide external users with overall 900 instrument days annually of trans-national access (TA) to the research environment of the core consortium of high-level RIs in EU-NMR;3. Develop core technologies to increase the scope, application envelope and quality of access for RIs in bio-NMR with respect to:a. Fast, efficient data acquisition modalities for multi-dimensional NMR to establish an efficient and cost-effective service network;b. Strategies to exploit hetero-nuclear Magnetic Resonance in Liquids and Solids;c. Integration and development of solid-state NMR structural data into a common software pa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'RE@CT - IMMERSIVE PRODUCTION AND DELIVERY OF INTERACTIVE 3D CONTENT' in the context of a Seventh Framework call.

assistant: **Objectives**

RE@CT will introduce a new production methodology to create film-quality interactive characters from 3D video capture of actor performance. Recent advances in graphics hardware have produced interactive video games with photo-realistic scenes. However, interactive characters still lack the visual appeal and subtle details of real actor performance as captured on film. In addition, existing production pipelines for authoring animated characters are highly labour intensive.RE@CT aims to revolutionise the production of realistic characters and significantly reduce costs by developing an automated process to extract and represent animated characters from actor performance capture in a multiple camera studio. The key innovation is the development of methods for analysis and representation of 3D video to allow reuse for real-time interactive animation. This will enable efficient authoring of interactive characters with video quality appearance and motion.The project builds on the latest advances in 3D and free-viewpoint video from the contributing project partners. For interactive applications, the technical challenges are to achieve another step change in visual quality and to transform captured 3D video data into a representation that can be used to synthesise new actions and is compatible with current gaming technology.RE@CT gathers a team of world leading researchers and companies in motion capture, 3D video, broadcast and interactive animation to develop a new production pipeline, including new temporal 3D matching methods, a new data representation for 3D action and an immersive visual feedback system as a production aid for actors. The project results will be demonstrated in two application scenarios: An augmented reality application will demonstrate usage for serious
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Genetically modified organoids for genetic variant interpretation in colorectal cancer' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Implementation of next generation sequencing to genetic diagnosis and precision medicine has revolutionized the fields of hereditary cancer and oncology, increasing exponencially the identification of genetic variants of uncertain significance. Their classification is one of the most relevant and urgent challenges we face, since decision-making in the clinics depends on it. Evidence obtained from empirical functional studies is essential to reach a definitive classification; however, clinical relevance of such studies is currently low due to lack of standardized tests, use of inadequate models, and tediousness and cost- and time-inefficiency of available assays. Organ-VIP aims at surpassing the barriers we face when using and implementing functional assays for the interpretation of genetic variants in colorectal cancer (CRC) genes. State-of-the-art methodological and conceptual developments will facilitate the development of a screening platform to interpret the pathogenicity of variants in any CRC gene. To do so, we aim to: i) Use a model that faithfully represents the target tissue and genetic context (CRISPR/Cas9-edited human normal colon organoids); ii) Optimize end-point assay(s) to maximize performance, implementation, robustness and agreement with clinical evidence; iii) Assess genetic variants in hereditary CRC and polyposis genes; and iv) Calibrate the results for implementation in variant classifiers. Organ-VIP integrates clinical aspects, molecular and cell biology, next generation sequencing, and advanced bioinformatics analysis. The platform will not only be useful for variant interpretation in germline and somatic testing, but also for functional evaluation of new candidate CRC genes. In the longer term, Organ-VIP will become high-throughput by the impleme