RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'The Evolution of Case, Alignment and Argument Structure in Indo-European' (EVALISA).

assistant: **Innovation**

Alignment and argument structure lies at the heart of all current theoretical models in linguistics, both syntactic models and research within typology. In spite of that, no large-scale comprehensive study of the historical development of case marking and argument structure has been carried out in modern times, using modern linguistic approaches and frameworks, and covering an entire language family from its first documentation until modern times. The project EVALISA aims to investigate case marking and argument structure from a historical perspective, or more precisely non-nominative case marking of subjects, focusing on its development through the history of the Indo-European languages. One of the products emerging from the project is an electronically searchable database of predicates taking non-nominative subject marking, available to the research community at large, for further research on the topic. Another product is a typology of grammaticalization paths of non-nominative case marking of subjects. This is a timely enterprise given that non-nominative subject marking is extremely common in the languages of world. A third product is a methodology for reconstructing syntax and grammar, based on the tools of Construction Grammar. The theoretical framework of Construction Grammar is easily extendible to syntactic reconstruction, due to the basic status of form–meaning pairings in that model, and hence the more lexicon-like status of the grammar. This creates a natural leap for Construction Grammar from synchronic form–meaning pairings to historical reconstruction, based on form–meaning pairings. This methodology is of importance for scholars within anthropological linguistics, working on the history of oral or less-documented languages.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Optimisation of protein crystallisation for European structural genomics' (OPTICRYST) targeting Sixth Framework.

assistant: **Abstract**

The OptiCryst STREP aims to take a leap forward scientifically and commercially to obtain high-quality crystals of proteins which are proving difficult to crystallise, providing a support platform for Europe's Structural Genomics initiatives that are struggling to deliver structures. Protein crystallisation has gained a new strategic and commercial relevance in the post-genomic era due to its pivotal role in Structural Genomics: producing high-quality crystals has always been a bottleneck to structure determination and this problem is becoming increasingly acute within worldwide initiatives. This is especially true for challenging therapeutically important proteins that typically do not form suitable crystals. It is clear that the only way to relieve the bottleneck of crystallisation is to focus a concerted effort on the science that underlies it. Research advances in recent years have opened up the scope for development and commercialisation of new tools and methods to adopt this relatively unexplored approach. 7 research-intensive SMEs' from 5 European countries (holding 54.4% of the total budget) and 4 research institutions' scientific expertise will reinforce technological knowledge and the validation of innovative solutions. The SMEs play leading roles and one is the coordinator. Opticryst will capitalise on this momentum and prevent difficult proteins from being consigned to Structural Genomics's 'back burner'. Opticryst has 2 key objectives: Develop and commercialise new, improved methods and equipment to obtain high-quality crystals of proteins difficult to crystallise; develop a platform for supporting the Structural Genomics initiatives in Europe struggling to deliver the number of structures that was hoped for. In conclusion, OptiCryst is designed to establis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Advancing the use of noble gases as paleoclimate indicators'.

assistant: **Innovation**

The analysis of dissolved noble gas concentrations in groundwater has proven to be a reliable method to determine quantitative paleotemperatures. Noble gas studies in semi-arid regions have shown that in addition to recharge temperatures, the excess air" phenomenon may be useful as a proxy for the important climate parameter humidity. A better understanding of gas partitioning during groundwater infiltration is a prerequisite for the reliable use of noble gases as paleoclimate proxies. In addition, such an understanding is important for several gas-tracer based methods for age-dating shallow ground waters (3H-3He, CFCs, SF6).The present project aims at advancing and broadening the scope and applicability of noble gases in paleoclimatology and hydrology, in particular at establishing the paleoclimatic significance of excess air. The primary goal is to obtain a detailed understanding of the physical mechanisms linking climate and soil parameters to the noble gas patterns imprinted during groundwater recharge. This objective shall be achieved by careful analysis of noble gas, climate, and soil data from several semi-arid regions, complemented by experiments on the scale of laboratory soil columns and test-fields.In order to study the distribution of noble gases in pore water with high resolution, improvements of sampling and analytical methods are planned, aiming at reducing the sample size. Such developments will provide a strong methodical link to concurrent efforts to the advancement of applications of noble gases in environments other than groundwater. Hence, this project is also expected to contribute to the development of new applications of the noble gas thermometer to important climate archives such as sediment pore waters or fluid inclusions in carbonate s inters.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Quantification of Free and Bound Water Concentrations in Human Cortical Bone Employing Hybrid Hard-tissue MRI: Towards Comprehensive Osteoporosis Assessment' (ROCHESTER).

assistant: **Innovation**

Osteoporosis weakens bones and increases the risk of unexpected fractures. Worldwide, it causes over 8.9M fractures annually. Cortical bone consists of 3 major parts; minerals, organic matrix and water. Bone Mineral Density (BMD) is the most widespread marker to assess bone quality. There is recent evidence, however, that bone mineralisation offers only an incomplete view of bone quality. In turn, bone water (including free and bound water molecules) does convey richer information about bone quality by probing both bone porosity and the organic matrix.We propose to develop a novel diagnostic imaging technique based on Magnetic Resonance Imaging (MRI) that offers a comprehensive assessment of cortical bone quality and osteoporosis. The quantification of free and bound water molecules in cortical bone will be done in vivo as their alternation are potential biomarkers of the cortical bone quality. We will use hybrid hard-tissue MRI to capture information from short transverse-relaxation time (T2) species. We will develop MRIstrategies that will go beyond the state-of-the-art in imaging bone tissue (herein referred to as “hard-tissue MRI” employing novel pulse sequences from the ultra-short echo-time (UTE) family. A key novelty lies in the hybridisation of UTE/short echo time (STE) acquisitions. By solving a set of coupled equations derived from these acquisitions using machine-learning techniques, we will define new quantitative imaging biomarkers associated with cortical bone free and bound water concentrations.The biomarkers will improve diagnosis of osteoporosis and alleviate its burden on healthcare systems (€37Bn cost to EU in 2010). It offers further potential in assessing bone development in pediatric imaging where ionizing and invasive methods cannot be employed. T
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Enterprise Europe Network Eastern France services for Innovation' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Delivery of Innovation specific support services in the Framework of Enterprise Europe Network activities in the two régions of Eastern France : Bourgogne Franche-Comté and Grand Est.These specific services concern on the one hand enhancing the innovation management capacity of SMEs on the other hand to carry out Key Account Management for SMEs benefitting grants from the pilot European Innovation Council scheme to assist them in receiving appropriate coaching services.


**Keywords:** innovation management capacity, KAM, EIC, SME Instrument
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Alliance for Family Integrated Care (FICare) Implementation in Neonatal Intensive Care Units', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Preterm births are the major cause of infant mortality in both developed and developing worldwide countries and one of the main concerns of public health systems. Very low birth weight infants and new-borns who suffer severe acquired diseases, congenital malformations or rare diseases face similar burdens and challenges. Altogether can be referred as “high-risk neonates”. These neonates have to spend long periods at Neonatal Intensive Care Units (NICUs) and, even so, they are at risk of developing short- and long-term health problems. This fact provokes suffering (e.g. anxiety, stress or trauma) to high-risk neonates’ parents and stressful situations, including burn-out, to NICU clinical staff. To overcome this, a Family Integrated Care (FICare) model that involves parents as primary caregivers in NICU teams has been recently developed with very promising results.RISEinFAMILY, a 52-months research project, aims to  undertake an implementation study of the FICare model to make it suitable to all environments (no matter the country or the NICU) and set it as the new international standard of neonatal and family care.A geographical, social and cultural diverse consortium composed of 12 partners from 4 high- (ES, NL, UK, and CA), 2 middle- (RO and TR) and 1 low-income (ZM) countries will scale-up and adapt the FICare model for the first time in Europe, Africa and Asia.  About 2800 infants will be assessed and clinical staff and families from at least 1600 high-risk neonates trained and educated for enrolling in 7 pilots worldwide (5 in non-FICare and 2 in FICare NICUs).Using mixed-methods research, the project will assess the impact of RISEinFAMILY in infants’ health (during NICU admission and after discharge), families and healthcare professionals experience from a psychol
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Reporter models for the Evaluation of Diseases involving OXidative stress' (REDOX).

assistant: **Innovation**

Perturbations in cellular redox status are implicated in many human diseases, yet there is an extreme lack of knowledge about the effects of oxidative stress in vivo, mainly due to difficulties in measuring reactive oxygen species (ROS) in vivo and the absence of experimental models.  REDOX will use novel transgenic technologies to develop mouse models that report on ROS in vivo, allowing spatio-temporal monitoring of different types of oxidative stress, ultimately simultaneously in a complex reporter line, and clarifying its role in the aetiology of disease and pathways of drug & chemical toxicity. These models will reveal oxidative stress as a primary cause, or a consequence, of the disease process.  Reporters will be driven by endogenous genes regulated by different forms of oxidative stress and, uniquely, we will exploit the sophisticated redox sensing systems in bacteria to discern different types of ROS. In a sophisticated system we will express 3 reporters from the same stress regulated promotor, generating a polycistronic mRNA by use of the FMDV 2A sequence, which cleaves the nascent polypeptide to yield the endogenous gene product and individual reporters. LacZ will be used as an in situ reporter, luciferase for imaging, and a secreted protein, eg hCG, as a non-invasive biomarker in blood or urine. The in vivo role of oxidative stress in disease aetiology, and the potential of novel anti-oxidants to prevent such diseases, will be evaluated in these models. A further novel aspect will be to generate ES cells from the reporter lines, and create genetically-driven disease models which reflect inherited human diseases.  REDOX combines ambitious experimental systems with sophisticated novel technologies to create models to define the role of oxidative stress in huma
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'NanoElectronics Roadmap for Europe: Identification and Dissemination'.

assistant: **Objectives**

The objective of this project is to elaborate a new roadmap for Nanoelectronics, focused on the requirements of European semiconductor and applications industry, and the advanced concepts developed by Research centers in order to achieve an early identification of promising novel technologies, and cover the R&D needs all along the innovation chain.The final result will be a roadmap for European micro- and nano-electronics, covering all TRL, with a clear identification of short, medium and long term objectives. The roadmap will be divided into main technology sectors and include also cross-functional enabling domains.A proper dissemination of results will take place through the close relationship of the project with the leading European organizations in the field of micro- and nano-electronics, and sanity checks are foreseen during the project with the users’ world.


**Keywords:** Roadmap, semiconductors, CMOS, sensors, power, beyond CMOS
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Development and drought responses of tomato exodermis', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Understanding plant development and responses to the environment is key for improving crop yields and ensuring food andfuel for the future. Many crop species have evolved adaptations that make them more tolerant against abiotic stresses, suchas drought, flooding and soil salinity. One of these adaptations is the exodermis, a water- and air-proofed cell layer in theroot that protects the root from drying and drowning. Although the importance of exodermis for crop yield has been shown,the development of exodermis is not understood on molecular level, likely due to its absence from the root model speciesArabidopsis. TOMATO EXODERMIS aims to elucidate the genes involved in exodermal development and drought responses in tomato. To achieve this, novel tools are combined in an efficient way to study root development of a crop species in a short timeframe. These tools include e.g. bioinformatic analyses of new cell type-specific datasets, rapid hairy root cultures and genome editing. TOMATO EXODERMIS will lay a foundation for an exodermis research program in European Research Area and generate potential for agricultural applications.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Medieval Publishing from c. 1000 to 1500' (MedPub) under Horizon 2020.

assistant: **Objectives**

Without written transmission, the communication of any learned topic from ancient and medieval times, from theology and philosophy to medicine, science and history, would be snapped and broken. Transmission relies on the fact of ‘publication’. But what does ‘publishing’ mean in the context of a manuscript culture, in which books were copied slowly and singly by hand? What did it mean to ‘publish’ a book in Western Europe in the Middle Ages? MedPub attempts to understand in breadth and depth, for the first time, the medieval act of publishing. The question it seeks to answer is how did Latin authors publish original works during the period from c. 1000 to 1500. The project’s research hypothesis is that publication strategies were not a constant but were liable to change, and that different social, literary, institutional, and technical milieux fostered different approaches to publishing. The act of publishing, therefore, evolved over time, reacting to changes in the wider world. This is a new proposition and opens a new field of study. Results from the project will make a major contribution to our perception of medieval Latin literature—which is the largest surviving body of evidence for the Middle Ages—and even medieval European societal dynamics. The time-frame, c. 1000–1500, embraces Latin literary culture in its high-medieval maturity and its more complex late-medieval developments, ending with a transitional period characterized by the co-existence of the manuscript book and the printed book and witnessing the emergence in Europe of what was to become modern publishing.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'International Network on Integrated Techniques in Structural Elucidation' under Seventh Framework.

assistant: **Concept**

Structural determination of complex chemical compounds is a difficult task and involves the combined use of several tools rooted in different physical principles, many of them classify like spectroscopies as they involve interaction between molecules and electromagnetic radiationWe propose a research program based in 3 major topics in configurational and conformational molecular elucidation. The 1 is centered in nuclear magnetic resonance (wp1), principally involving preparation and testing of novel NMR alignment media and the development of new software for structural analysis automation procedures. Shape-persistent acetylenic macrocycles and polyaromatic structures can provide ordered systems in which constitution, physical properties, and chemical reactivity can be controlled in exquisite detail. Thus in WP2 synthesis and structural elucidation of π-conjugated systems tailored to exhibit specific properties will be addressed involving information gathered from NMR, chiroptical and electrochemical analyses. The 3 topic focuses on the analysis of chiroptical properties (WP3): ORD, ECD and VCD data will be used with the help of quantum mechanics not only for conformational and configurational characterization in combination with NMR, but also to elucidate the origin of the observed chiralityInTECHSE will offer a unique opportunity for the synthetic chemists to learn basic aspects of structural information obtained by magnetic and optical spectroscopies in which experimental measurements are colligated with theoretical calculations. Theoretical chemists will benefit from the possibility of designing together with the synthetic chemists systems for gaining understanding on the mechanisms responsible of chiroptical responses and appropriated methodologies for structural ch