RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Innovative low-valent tetrylene photo- and cooperative catalysis via a rational design of ligands.' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Catalysis is a key technology in the European economy, industry and sustainable growth for a resilient future. However, many catalytic methods in use today are not outstanding in fundamental aspects such as activity, selectivity, substrate scope, toxicity or even cost efficiency. The rich structural diversity and associated reactivity provided by heavy elements from the Main Group offer unique opportunities for the prospective substitution of traditional catalysts based on precious metals by less expensive, more abundant, and potentially less toxic Main Group compounds. Sub-valent Ge(II) and Sn(II) derivatives are particularly appealing due to their reduced HOMO-LUMO gaps and thus increased reactivity. Nevertheless, bond activation processes lead to very stable and unreactive products in higher oxidation states (+IV). As such, catalytic turnover via reductive regeneration of the active species is highly challenging. To address this problem, an interdisciplinary approach will be used combining fundamental aspects stemming from a priori independent areas of Chemistry. Rationally designed ambiphilic and bifunctional derivatives will be used as ligands for low-valent tetrylenes to induce cooperativity between Main Group elements and Transition Metals and promote novel reactivity in small molecule activation and functionalization. Another objective is to demonstrate that selective irradiation of well-designed mononuclear tetrylene will allow photoactivation of chemical bonds that are thermally inert towards many of these divalent species. However, we envision that the main advantage of using light will be in facilitating reductive elimination processes in the cases where thermal catalytic turnover is hampered by this rate-limiting step. For this reason, these studies will al
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'An innovative Computational PLAtform for solving differential Equation of modelling BiOmedical processes' (PLACEBO) targeting Fifth Framework.

assistant: **Abstract**

Biomedical modelling and simulation is a significant area in biomedical engineering used to advance the quantitative understanding of biological functions and to improve medical science and practice by utilising the acquired quantitative knowledge. It aims at analysing and explaining complex properties and functions of biomedical systems. The resulting mathematical models, specified using differential equations, ought to emulate the observed functional behaviour of the system under experimental conditions. Surgeons, for example, have to make their choice during operation among different implants and they need a complete and reliable environment in which can perform simulation of the realistic conditions in almost real-time.Objectives:The major objective of the PLACEBO project is to develop an advanced high performance computational environment for solving ordinary or partial differential equations using techniques based on neural network models. It will constitute a computational framework that will assist both doctors and bioengineers into experimentally studying and analysing complex biomedical models in an easy-to-use and efficient way. In addition, the proposed project aims towards improving the performance of existing embedded systems, which are based on advanced biomedical signal processing applications and at the same time stimulating support for related software and hardware technologies.Work description:The work in this project is divided into four phases. The first phase is related to horizontal co-ordination and project management. It covers the general management tasks, the official contact with the European Commission, including the preparation of reports. It also covers the technical and quality assurance co-ordination to ensure the necessary interaction a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Recycling light metals for high value-added use'.

assistant: **Objectives**

Fellowships are offered on research solving problems in recycling of light metals aluminum and magnesium. European researchers are invited to join the integrated research groups at NTNU (Norwegian University of Science and Technology) and SINTEF (Materialteknologi) in Trondheim, Norway, and take part in research activities covering both fundamental and applied aspects on improving and developing technology for laser/image analysis sorting, refining, alloying and casting of recycled light metals. Extensive research is to be conducted on the solidification behaviour, phase transformations, mechanical processing, and materials modelling and surface properties. The activities range from fully automated laboratory studies to mathematical modelling and numerical simulation. The experimental work will mainly be carried at the Institute for Materials Technology and Electrochemistry. The Institute has a large professional staff of 18 professors, 36 Ph.D students, and 10 technicians. There is a full range of laboratory equipment, including new foundry and refining furnaces to a full range of the newest scanning and transmission electron microscopes. Particularly challenging current fields of research are optical automated sorting of scrap including separation of alloys removal of iron, tin and lead from recycled aluminium in continuous counter flow units, development of environment-friendly methods for protecting molten magnesium, a new technique for direct imaging of solidification, in-site studies of deformation in the scanning electron microscope, problems due to accumulation of tramp elements such as iron and copper in recycled metals, development of through process models to cover the entire processing route from sorting of scrap to forming the finished product, characteriza
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Precise orbit determination for the moms/priroda camera experiment based on dgps carrier-phase and pseudorange measurements' under Fourth Framework.

assistant: **Concept**

The MOMS-2P system, an advanced high resolution 3-line stereo scanner for Earth observation, will fly on-board the MIR space station (1996), augmented by a navigation package. The navigation information, required for the reconstruction and evaluation of the collected images, is provided by a GPS receiver. The aim of the research is to implement and validate a completely new concept, which combines the orbit determination and image reconstruction process to improve the accuracy of stereoscopic image products. Emphasis will be on the precise orbit determination of MOMS, fully exploiting the GPS carrier-phase and pseudorange measurements complemented by groundbased GPS measurements, in a differential GPS (DGPS) approach. In contrast to the well-known kinematic Earth based DGPS approach, a dynamical modelling of the spacecraft motion is required. By adopting the proposed DGPS approach, the orbit determination accuracy is expected to improve from 100-200 m to better than 5 m, eventually enabling us to better monitor our world.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Dynamic cell coordination in the plant root'.

assistant: **Innovation**

The fellow proposes to spend a year at the Centre for Plant Integrative Biology (CPIB) at the University of Nottingham, UK, studying the coordination of cellular behavior in the plant root. The coordination is dynamic, poorly understood, and exploited by the root as it responds to environmental stress. The project represents a multi-scale, integrative analysis–relevant throughout biology–that will help improve root traits–essential for tomorrow’s agriculture. The fellow brings to the UK expertise on plant growth and kinematic analysis, expertise that will further the research mission of CPIB as well as be beneficial for European scientists. The fellow’s career will be enriched by immersion in a truly multi-disciplinary environment. Growing roots will be recorded with confocal fluorescence microscopy and image-analysis methods will be developed to quantify growth at a cellular scale. Cellular growth patterns will be characterized as the root responds to its environment (drought). A computer model will be developed to simulate complex dynamics of cellular behavior during root growth and to support mechanistic hypotheses about the underlying causal behavior. This project requires apparatus at CPIB as well as their multi-disciplinary expertise on roots, image analysis, and modeling. The fellow will engage the public through established outreach events run by CPIB. Major deliverables will be software for quantifying growth on a cell-by-cell basis, a model for dynamic cell behavior in the root, and a quantitative understanding of cellular dynamics underlying the root’s response to stress. Software will measure growth at higher resolution than previously and will be widely useful, even for animal biologists. Understanding cellular dynamics underlying the root’s response to str
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Inside the bi-dialectal mind and brain: An electrophysiological study on executive functions' in the context of a Horizon 2020 call.

assistant: **Objectives**

There is widespread impression in Western societies that monolingualism is the norm, but in fact most people function in multilingual and/or bi-dialectal settings. Recently, there has been an upsurge of research on the cognitive effects of bilingualism, with several studies reporting an enhancement of executive control skills in bilinguals. In contrast to bilingualism, however, bi-dialectalism has so far received essentially no research attention. In this context, NeuroBid proposes a multidisciplinary approach that uses both cognitive assessments and electrophysiological measures (Event-Related Potentials) to achieve four goals. The first aim is to characterise the profile of bi-dialectals at both the cognitive and the neural level, focusing on a specific neuro-cognitive system, executive control (EC). In achieving this goal, a second aim will be accomplished, to establish the effect of language similarity on the neuro-cognitive outcomes of bilingualism. The third goal is to explore previous failures to replicate the bilingual cognitive advantage in EC with young adults and to determine whether a bilingual benefit will indeed surface when an experiment that avoids several methodological drawbacks of previous research is implemented. The final aim is to provide data to adjudicate between theoretical accounts regarding the specific locus of the bilingual EC benefit. With a fellowship to implement NeuroBid, the Candidate will provide results and publications that will contribute to a better understanding of the bi-dialectal mind and brain, and will answer important, theory-relevant questions in the neuro-cognitive research on bilingualism; he will also acquire new competences in neuroscientific tools, and receive training in key transferable skills. This will strengthen hi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Isogeny-based Toolbox for Post-quantum Cryptography', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

A quantum computer exploits quantum-mechanical effects such as superposition to solve hard mathematical problems that are intractable on classical computers.  The most prominent example is Shor's algorithm that renders all widely deployed cryptographic systems such as included in TLS totally insecure, and thus also all digital services that crucially rely on them.Post-quantum cryptography deals with the design and analysis of cryptographic algorithms that remain secure against attacks not only by classical computers, but also by quantum computers.  The threat of quantum computers is a very real and pressing issue as evidenced by the ongoing NIST standardization effort for post-quantum cryptographic algorithms.Isogenies are maps between elliptic curves, and hard problems related to the computation of such maps, have recently been proposed as a candidate for post-quantum cryptography.  Due to its versatility, isogeny-based cryptography has the potential to become the only fully fledged alternative to lattice-based cryptography, providing much needed diversity.The goal of ISOCRYPT is to develop the full potential of isogeny-based cryptography into a secure, efficient and practical approach to post-quantum cryptography, and to provide a toolbox to easily instantiate secure isogeny-based applications.  To achieve this goal, a number of key research challenges need to be solved: determining the exact security of isogeny-based systems, providing efficientand secure implementations and building a suite isogeny-based post-quantum secure applications.  Our approach to solving these challenges relies on a deep exploration of the mathematical properties of isogenies, guided by the functionalities needed to build practical applications.This proposal will build on the renowned expert
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Phase behaviour and structure of colloidal suspensions' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Research objectives and content Colloidal suspensions are complex fluids, that consist of mesoscopic particles suspended in a solvent. Direct simulation is impossible as different length and time scales are involved. The present understanding is based on simplified models in which the mesoscopic particles interact with effective potential. However, it turns out that the phase behaviour of these models depends strongly on the details of the effective potential, and that a variety of phenomena is still unresolved. A better understanding of the effective potentials is essential. In this proposal, we will construct theories based on density functional theory (DFT) and on analogies with confined fluids for the effective potentials between the mesoscopic particles. The phase behaviour will then be determined by performing computer simulations in this effective two-body description. However, it is known that this approach of effective potentials fails at high concentrations and high surface charges. For these cases, a new simulation tool will be developed. Training content (objective, benefit and expected impact) This project should lead to the resolution of one or more open questions in colloid science and should shed new light on experimental observations. The applicant will gain fresh and detailed knowledge of the statistical mechanics of confined fluids and the framework of DFT. Also a broader overview and a deeper insight in the field of complex fluids will be gained by working on current problems in the field of sterically and charged stabilised colloids. Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Hegel's Philosophy of Biology' (HoBi).

assistant: **Innovation**

The project addresses Hegel’s philosophical stance concerning the nature of organismic life, which in contemporaryterms might be defined as his philosophy of biology. It asks how Hegel assesses the ontological status of living organisms, the purposive features of living systems, and the relation between life and cognition. It further asks whether Hegel’s philosophy of biology can be interpreted as a theory of biological autonomy. While extensive literature has been devoted to Kant’s philosophy of biology, Hegel's work on this topic remains largely unexplored. This is due to a long-lasting preconception against his philosophy of nature, which originated in the nineteenth century and still reigns today. The challenge of the project is to remove this preconception. The term “biological autonomy” was coined by biologists Humberto Maturana and Francisco Varela to define the ability of a living system to produce and maintain itself. My working hypothesis is that the framework of biological autonomy provides the most effective template for re-reading Hegel today and that Hegel’s theory of biological individuality is extremely useful for those who aim to lay the philosophical groundwork for the articulation of a biologically compelling theoretical alternative to the mechanistic conception of life.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Streamlined Functionalisation of Nitrogen-containing Molecules by Palladium-catalysed C-H Activation' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Transition-metal catalysed C-H activation is a powerful tool to functionalise and derivatize organic molecules at seemingly inert sites. The strategy opens new efficient synthetic routes to existing molecules and provides access to novel ones. Our aim is to develop palladium catalysed sp3 C-H activation technology for the synthesis of nitrogen heterocycles and for the derivatization of simple secondary amines to high value molecules. Our proposal will address demand in the pharmaceutical industry for the efficient synthesis of nitrogen-containing molecules to aid medicinal chemistry and accelerate the drug discovery processes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Decrypting Mycobacterium cytochrome P450 (CYP) physiological functions by testing hypotheses emitted form large-scale comparative genomics analysis' in the context of a Horizon 2020 call.

assistant: **Objectives**

More than 190 species belong to the Mycobacterium genus. Among those, several are pathogenic to human and animals. The high number of human lives lost and the economic consequences of livestock infection are important incentives in the control and eradication of the responsible organisms. M. tuberculosis, one of the causative agents of tuberculosis (TB), is the most problematic representative: in 2016, 1.7 million deaths worldwide have been attributed to TB. Like for other infectious organisms, antibiotic resistances have appeared in Mycobacterium. Thus, there is a fundamental need to develop new antimycobacterial drugs. The inhibition of enzymes belonging to the Cytochrome P450 (CYP) protein family has been shown to suppresses the growth of several Mycobacterium species, making CYPs targets for drug development. Unfortunately, most CYPs are considered orphan: proteins for which no physiological function is known. The deCrYPtion action aims to define the physiological function of a selected set of mycobacterial CYPs. It will prove determinant in the development of new antibiotics. I will perform a large-scale comparative genomics analysis of the CYPs encoded by Mycobacterium species, in order to define orthologous groups and identify, for each, conserved partners and pathway context. This approach is extremely powerful (even if not frequently used) and allow to propose physiological functions, based on the information obtained. Specific CYPs to be characterized will be selected based on a set of stringent considerations, including their potential as drug targets. A preliminary analysis illustrates the approach that will be used. A combination of complementary biochemical, genetics and physiological experiments will be performed to validate the hypotheses generated. deCr