RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Risk-aware Automated Port Inspection Drone(s)' (RAPID).

assistant: **Innovation**

RAPID will save lives by delivering an early warning system that will detect critical deterioration in transport system infrastructure, while also minimising system disruption and delays to critical supply chains. It will achieve this goal by combining and extending state-of-the-art drone technology to deliver a fully automated and safety assured maintenance-inspection (MI) service for bridge inspection, ship hull surveys and more. By combining self-sailing unmanned surface vehicles (USV) with swarms of autonomous unmanned aerial systems (UAS), RAPID will dramatically cut the time and cost of structural condition monitoring. RAPID-enabled MI services will increase efficiency and competitiveness for maritime transport stakeholders – such as ports, shipping companies, and landside transport authorities – and will deliver the safe and seamless operation of supply chain and mobility infrastructures – such as material handling equipment, cargo and passenger ships, and bridges. It encourages prioritisation of safer transport infrastructure where the technology seeks to improve environmental impact. The attractive return on investment will enable RAPID to gain market traction and incentivise commercial proliferation, bringing RAPID into widespread use for the overall benefit of society. By 2028, a newly formed company will generate €124 million and save in the order of 100 lives per year (reaching c. 20% share of the serviceable addressable maritime transport market through strategic partnership with 50 ports). RAPID brings together interdisciplinary partners with the expertise and capacity required to develop and validate this unique service model.  The project will develop the consolidated maritime and aviation regulation standard for safe USV / UAS operations and the busine
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Ecological treatment of biowastes to biofuel' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

The presented project is intend on the material utilisation of bio wastes, particularly the wastes from municipal sphere and from the food - processing, chemical and pharmaceutical industry, particularly the sludge the properties of which do not correspondent to the possibility of their use in agriculture. The basic principle of the bio fuel production from the waste sludge and other bio wastes consists in the creation of the optimum conditions for the short - term aerobic fermentation of the mixture of dewatered sludge with solid bio wastes, with its help in comes to the deodorisation simultaneously with higher water evaporation and the fermented mixture can consequently be desiccated on the drier without air contamination. The development of cogeneration pilot plant for the electric and thermal energy production by the use of bio fuel with a view to the house building and industrial buildings.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'All-in-one surface methodology for corrosion protection in Metal Additive Manufacturing' to be submitted under Horizon Europe.

assistant: **Abstract**

Metal Additive Manufacturing (MAM), also known as 3D metal printing, has attracted a great deal of attention from scientists and industries due to its potential in the state-of-the-art production of complex-shaped designs in the transport industry. MAM is considered the fundamental technology for Industry 4.0 since it is a low-cost and energy-efficient processing method for metallic components with a minimal environmental impact. Nevertheless, the surface finishing of MAM components is uncontrolled during the fabrication, resulting in low corrosion-resistant components. So far, current post-surface treatments are non-eco-friendly, non-energy efficient, and the achieved corrosion resistance does not fulfil the service life requirements. In this scenario, the main goal of the SuMAM project is to achieve the full exploitation of MAM in the transport industry following the European Green Deal. Namely, as a major innovation, we will develop an innovative All-in-one methodology to achieve the highest corrosion resistance during printing, removing the need for post-treatment.  We will combine two approaches: surface creating by (i) in-situ laser processing and (ii) incorporation of additives during printing to control the surface without affecting the bulk properties of the final components. Our target materials are four aluminium alloys and one stainless steel, widely used materials in the transport industry.This project is an outstanding opportunity for the fundamental advancement of MAM science by a technological and economically feasible methodology. The SuMAM project presents the best research scenario for Dr. Rubén Del Olmo Martínez (candidate) to further develop his scientific career. The SuMAM project is led by Prof. Dr. Ir. Iris de Graeve and Prof. Dr. Ir. Herman Terr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Market Opportunity Confirmation for Biomimetic Tissue Matrix Products'.

assistant: **Concept**

A variety of in vitro human tissue models are used in the fields of testing of cosmetics products, drug discovery and regenerative medicine.  Most models made from artificial materials do not properly reflect the native tissue morphology and cell composition, while those made of seeded cells/tissues of specific organs lack versatility and are expensive to use.  Ferentis’ Biomimetic Tissue Matrix (BIOTIMA) project addresses the need for efficient toxicity testing/cell culture tools enabling more physiologically relevant, predictive and functional tissue mimicking models, that should become the EU standard in its effort to reduce expensive and inhumane animal testing. Ferentis scientists have developed an innovative patent-pending biosynthetic material –a bioplastic- that is cell-free, stable, biocompatible and optically clear and has demonstrated clinically to promote regeneration of cells. By employing advanced surface nanoengineering techniques, this biosynthetic hydrogel can be deposited, functionally modified and patterned on different substrates, for a variety of lab tissue experiment applications.  The unique advantages of our tissue matrix include unique biomimetic properties, most closely mimicking those of the real tissue, and advanced nano-fabrication methods, allowing a cost efficient, versatile and easy to use solution. The prototypes of our TM cell culture tools have been demonstrated in relevant testing environments and now are being piloted with our early adopter customers, with a primary focus on the cosmetics industry. A thorough feasibility study and an elaboration of a business plan is needed in order to analyze the market, map and confirm commercialization alternatives and prepare the roadmap for scaling-up in preparation for Phase II, market replicat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Improvement of quantitative determination of volatile organic compounds in indoor air using gas chromatography- mass spectroscopy' (1994-1998).

assistant: **Concept**

The quality of indoor air, which has considerable influence on human's well-being and health is diminished by pollution with up to sixty volatile organic compounds (VOC). The determination of the pollutants is feasible using active and passive sample collection combined with gas chromatography - mass spectroscopy. One innovative goal of the proposed project is the development of a practicable calibration system allowing precise VOC quantification. This includes acquisition of intimate knowledge of identifying the various compounds. Another aim refers to the comparison of active and passive sampling methods in different fields of application. In this context sample preperation using thermal desorption or solvent extraction has to be valued. Furthermore sampling and determination of reactive substances i.e. alcohols and esters has to be improved. Reliable and reproduceable quantitative determination of VOC is desirable in order to establish equal legalized maximum concentration levels of indoor air pollutants in the whole Community.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'The role of the rhabdoid tumor suppressor hSNF5/INI1 in cell differentiation'.

assistant: **Innovation**

Malignant rhabdoid tumour (MRT) are highly aggressive malignant neoplasms of childhood. MRTs show great phenotypic variability in their tissue localisation and differentiation. This phenotypic diversity contrasts with a strong genetic homogeneity characterised by biallelic inactivation of hSNF5/INI1; a subunit of the SWI/SNF chromatin remodelling complex.This phenotypic variability means that it is unclear in which type of cells MRTs arise. The aim of this proposal is to elucidate how hSNF5/INI1 affects the differentiation of MRTs with a view to identifying an MRT progenitor cell and to examine the role and molecular mechanism of hSNF5/INI1 in various key differentiation programmes.Microarray expression analyses will be conducted comparing the transcription profiles of MRT lacking hSNF5/INI1 and of MRT cells manipulated to re-express hSNF5/INI1 with these of a variety of normal tissues and immature progenitor cells. In vitro differentiation experiments with MRT cell lines expressing a conditional version of h SNF5/INI1 will enable us to investigate the differentiation potentials of MRT cells from various origins (brain, epithelial, soft tissue).Furthermore, the requirement for hSNF5/INI1 in well-documented models of cell differentiation (PC12, 3T3L1, C2C12, mesenchymal stem cells) will be evaluated by specifically silencing hSNF5/INI1.These experiments will be combined with CHip on chip experiments (Chromatin Immunoprecipitation followed by microarray profiling) investigating the promoters bound by hSNF5/INI1 and temporal analysis of the gene expression profile of MRT cells following hSNF5/INI1 activation, this project should contribute to a better understanding of the cellular pathways controlled by hSNF5/INI1 and altered in MRT.Overall, the project should contribute t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Bio entrepreneur boot camp: starting life science companies'.

assistant: **Objectives**

The Life Sciences scientific community needs a lot of support in new and candidate member countries to change culture about the ways to commercialise research results and increase the number of SME's, and promote collaboration between academia and SMe's. The goal of Bioentrepreneur Boot camp is to help new member and candidate states to create more Life Sciences based companies, by providing the necessary knowledge and support to scientists of these countries to discover, understand and apply the methods needed to create sustainable start-up companies. This will be achieved by offering a two steps Boot camp": Step1 will provide participants enough knowledge of the eomy of a start-up for their future entrepreneurial life and helps them to avoid most common mistakes. Step 2 offers the opportunity to prepare the business plan of real projects that can reach the market, with experienced specialists, coaches with strong track records in the Life Sciences enterprises area. Participants in step 1 are scientists from Academia interested in setting up a company or involved in technology transfer from University or sidering joining structures like incubators. All of them need to acquire the basics of eomics of Life sciences based start-ups. Participants in step 2 are will be entrepreneurs who already attended the Bioentrepreneur Boot Camp for beginners or Biobiz workshop or have acquired the basics of entrepreneurship in Life Sciences and have started to prepare a business plan. After completing such boot camp, participants will be ready to present to investors with a very high chance of success. To adapt to new European text, Eurobiobiz plans to deliver Bioentrepreneur Boot camp over 28 month, starting January 2007, with a focus on new members, associated and candidate countries
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Structural change and environmental protection in selected basic industries' (1994-1998).

assistant: **Concept**

The project investigates the approaches to and the conditions for environmentally beneficial structural change in industrialised countries. It concentrates on industries which cause environmental problems significantly above average: the production of basic metals, petroleum products, paper, paperboard and pulp, cement, chemicals, electricity and the mining industries.OBJECTIVES: The project investigates the approaches to and the conditions for environmentally beneficial structural change in industrialised countries. It concentrates on industries which cause environmental problems significantly above average: the production of basic metals, petroleum products, paper, paperboard and pulp, cement, chemicals, electricity and the mining industries. DESCRIPTION: Structural change alters the nature and the extent of the economic system's interrelation with its natural environment. The project tries to answer four questions: i) what are the international and national patterns of change in the above mentioned ecologically intensive" sectors of industrialised economies ? ii) if there has been a decline in national production, what were the reasons for this development ? iii) how did the actors involved deal with the resulting problems ? iv) is it possible to use or to develop further, political strategies and instruments for the (political) management of structural change, i.e. for an ecological industrial policy, aimed at the reduction of material flows and related ecological risks ? The empirical analysis of selected industries in Austria, Denmark, France, Germany, Luxembourg and the Netherlands helps to identify relevant conditions for an ecological industrial policy. The discussion brings together the empirical findings and the state of knowledge in the social sciences regar
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Evolution of plasmid-mediated resistance in Pseudomonas aeruginosa'.

assistant: **Objectives**

Antimicrobial resistance in bacteria is currently one of the most concerning threats for public health. Up to 400,000 patients suffer from infections resistant to multiple antibiotics in Europe annually, giving rise to more than 18,000 deaths every year. Hence, a better control of the rise and spread of antimicrobial resistance in pathogenic bacteria is crucial to improve the health of European citizens. Bacteria acquire resistance to antibiotics through two principal routes, (i) chromosomal mutations and (ii) plasmid acquisition. Plasmids are extrachromosomal DNA elements responsible for the spread of antimicrobial resistance determinants among bacteria, as they can disseminate by horizontal gene transfer (conjugation and/or transformation).Previous works have shown that aspects as the mechanistic basis of drug resistance and the antibiotic treatment regimes are crucial for understanding the evolution of population genetics of chromosomal-mediated resistance. Here, we would like to determine the key population genetic parameters that influence the rising and the spread of plasmid-mediated resistance. Specifically, we will determine for both (a) plasmid and (b) chromosomal-mediated resistance:(i)The rate of acquisition of resistance.(ii)The fitness costs and benefits of resistance.(iii)The potential for compensatory adaptation to ameliorate the cost of resistance.We will quantify these parameters using in vivo and in vitro experimental evolution experiments with the pathogenic bacterium Pseudomonas aeruginosa.This work will help us to understand and prevent the concerning phenomenon of antimicrobial resistance spread among pathogenic bacteria, and will provide information of biological and clinical relevance to make predictions about how innovative therapeutic approache
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Unveiling human astrocyte states, functions  and their contribution to Alzheimer´s disease', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The pathogenesis of Alzheimer´s disease (AD) is not fully understood and no cure is available so far. Current therapeutic targets are insufficient and there is an urgent need for finding new pathways and mechanisms and novel targets to treat this terrible disease. Due to critical species-specific differences and the limitations of rodent models of AD, humanized models are necessary to capture the complexity of the disease process. My lab has pioneered the use of humanized chimeric mice to study human astrocytes (h-astrocytes), integral components of the brain and understudied in AD. I propose here to investigate with a multidisciplinary approach their contribution to AD development and progression. We have already showed the potential of chimeric mice to identify novel and unexpected contributions of h-astrocytes to AD pathology. hASTROCURE will take advantage of our unique model to drive breakthrough discoveries in our understanding of h-astrocytes and their role in AD. We will investigate in humanized chimeras what is the impact of the genetic make-up (risk vs protective variants in AD risk genes) on h-astrocytes molecular states and functions as disease evolves and how they contribute to pathological features and AD progression. The overarching aim is to dissect central pathways leading to h-astrocyte activation towards detrimental states and target those pathways, which can provide the necessary knowledge to enable the development of novel astrocyte-specific therapeutic strategies.This pioneering project involves a set of innovative approaches as an essential platform for studying human genetics in h-astrocytes, in an AD relevant context. My experience and the work that my lab has developed these last years support the conceptual basis of the proposal and demonstrat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Plasmonics of Quantum Materials: from surface plasmon condensation to quantum metamaterials' under Seventh Framework.

assistant: **Concept**

Interfacing quantum optics with nanotechnology could boost the prospects for the integration of scalable quantum information technologies. Quantum information processing is a key future technology that promises superior communication and computing performance beyond classical information. Any candidate to realize its full potential will require solid-state coherent units with long-range interactions. The most promising approaches rely on photons and spins.Recent demonstrations of the quantized character of surface plasmons – oscillations of electrons bound to photons – have spurred research in miniaturized quantum optics with plasmons, known as quantum plasmonics. Despite the interest, experiments aiming at nanoscale quantum circuits and communication with plasmons are still in their infancy because of the difficult generation of a coherent interaction between different single-plasmon nanosources.Here we propose a conceptually new route to quantum plasmonics that harnesses the properties of quantum materials. These are tunable quantum systems with properties that emerge from the strong interaction between coherent units, with macroscopic states that are determined by collective quantum many-body physics.We will create a unique quantum state: a Bose-Einstein condensate of surface plasmons for which quantum properties become apparent in a many-emitter system. This will allow the construction of a quantum metamaterial, a reconfigurable optical material that exploits coherence.Topological insulators – another fascinating quantum material that is metallic on its surface, insulating in its bulk and locks electronic spin to current direction – will be shown to support plasmons and spin-plasmons (a plasmon travelling with a spin wave). This will bridge spintronics and nanophoto