RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Matrix during cancer progression' (MATRICAN) targeting Horizon 2020.

assistant: **Abstract**

The extracellular matrix (ECM) is known to play a critical role in driving cancer progression, and yet we lack knowledge of its composition and structure. The goal of my ERC project is to investigate how alterations in biochemical composition and structural properties of the ECM during cancer progression impact on cell behaviour to drive metastasis, which is responsible for over 90% of cancer patient deaths. In order to do this, my lab has developed a method to in situ decellularise organs leaving structurally intact ECM scaffolds for subsequent analysis or for repopulation to study cell-ECM interactions in situ. We have deployed our method to decellularise primary tumour and metastatic organs in mice bearing orthotopic breast cancer tumours for subsequent quantitative global mass spectrometry (MS) proteomics, spatio-structural mapping of ECM components in 3D, and live imaging of repopulated cells. We observed fundamental alterations in ECM composition and structure between normal and tumour, and primary and metastatic tissue. We have selected two ECM components specifically upregulated in metastatic organs for subsequent validation. We discovered a marked decrease in proteins associated with fibrillogenesis in metastatic organs and will investigate the impact of this on metastatic ECM stiffness. We will decellularise organs from transgenic mouse models of breast and pancreatic cancer, at specific stages during cancer progression to determine the evolution of global ECM composition and structure, and how this impacts on cell behaviour through functional perturbation. Finally, we shall validate relevance of findings to human disease through use of human cancer lines and analysis of human patient samples. The research proposed will provide ground-breaking insight into how
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Causes and consequences of mechanisms underlying genome size obesity' (2007-2013).

assistant: **Concept**

There are compelling reasons to believe that many underlying genomic, cellular, developmental and ecological processes are genome-size dependent. Plants with large genomes are at greater risk of extinction, less adaptable to living in polluted soils, and less able to tolerate extreme environmental conditions, clearly demonstrating that genome size has ecological consequences which shape the distribution and persistence of biodiversity. This proposal addresses the mechanisms behind the dynamics of genome expansion, which in the plant genus Fritillaria includes species with giant (obese) genomes, at least 150-fold larger than model species such as Arabidopsis thaliana. We are profoundly ignorant of how their genomes expand. Until recently, the sheer scale of the task of understanding genome obesity was too daunting to address. But now that impediment is largely overcome thanks to the astonishing advances in next generation sequencing methods (NGS). This proposal exploits NGS along with complementary methodologies that survey entire genomes to provide insights into the evolutionary dynamics of genome obesity. We will test hypotheses that examine whether there are unusual or novel epigenetic events (i.e. siRNA, cytosine methylation, histone modifications) that contribute to the evolution of genome obesity. Lu Ma brings expertise in cytogenetics and immunocytochemistry, a skill set he will enhance during the Fellowship through the training received in the Leitch Laboratory. This will considerably enhance Lu Ma’s career prospects since he will emerge highly proficient in skills needed to analyse NGS data, an area where there is currently an acute shortage of trained scientists, despite the importance of NGS approaches in the future of modern biosciences. Overall, the Fellowsh
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The Roots of Mathematical Structuralism' (STRUCTURALISM) under Horizon 2020.

assistant: **Objectives**

Mathematical structuralism is a central position in contemporary philosophy of mathematics. It is the view that mathematical theories describe only abstract structures or structural properties of their subject fields. This project will investigate the mathematical and philosophical roots of structuralism in a ground-breaking way. The focus will be set on two historical developments in nineteenth century mathematics and early twentieth century philosophy of science: the first one concerns several conceptual changes in geometry between 1860 and 1910 that eventually led to a “structural turn” in the field. This includes the gradual implementation of model-theoretic techniques in geometrical reasoning, the study of geometrical theories by group-theoretic methods as well as the successive consolidation of formal axiomatics. The second development analyzed here concerns the beginnings of the philosophical reflection on structural mathematics between 1900 and 1940. This includes different attempts by thinkers such as Rudolf Carnap, Edmund Husserl, and Ernst Cassirer to spell out the philosophical implications of the new structuralist methodologies at work in modern geometry. The principal objective of the project is to provide the first comparative investigation of these early contributions to structuralism and their immediate mathematical background. The integrative study of the history and the philosophy of modern mathematics will not only change our conception of the evolution of the philosophy of mathematics in the twentieth century. It will also transform the ways in which we presently think about mathematics. Specifically, the project will provide new systematic insights relevant to contemporary structuralism, in particular a new understanding of notions such as mathemat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Physical and chemical characterisation of particle emissions from diesel driven vehicles' under Sixth Framework.

assistant: **Concept**

Driven by concerns regarding global warming, air quality and human health, there is a clear trend toward increased sales of light-duty diesel vehicles in many parts of the world. This trend can result in many positive environmental benefits including low fuel consumption, and therefore low levels of CO2, CO, HC and volatile hydrocarbons. However, increased diesel sales have a downside, relatively high NOx and particulate emissions.As a result, countries around the world are increasingly tightening diesel regulations with the result that engine and reducing emissions technologies continues to advance, and reformulated diesel fuels continue to appear. In this context, the overall objective of this research project is to characterise physically and chemically particulate matter (PM) emissions from light-duty diesel vehicles and engines.The research pretends to assist in the setting of future regulation limits on PM emissions for this type of vehicles, addressing last generation diesel engines (direct injection), advanced particle emission reduction technologies (diesel particle filters) and novel diesel fuels (biodiesel). For that purpose, a new system for PM sampling and measurement will be developed and assessed in order to allow for accurate, repeatable and reproducible measurements of particles in the exhaust of diesel vehicles, mostly in the ultrafine and nanometre range, at the low emission levels from the technologies anticipated for the future market and at the stringency levels expected in future legislations.The project will be carried out in the vehicle and engine emissions laboratory (VELA) at the Institute for Environment and Sustainability (IES) of the Joint Research Centre (JRC) of the EU in Ispra (Italy). VELA has facilities to test emissions from engines a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Methodologies for implementing international standards for Saffron purity and quality' (SAFFIC).

assistant: **Concept**

Saffron is the most precious and most expensive spice in the world. The greatest saffron producers are Greece, Spain, Turkey, Iran, India, and Morocco. The largest saffron importers are Germany, Italy, U.S.A., Sweden, Switzerland, U.K. and France. In the last years the fraudulent practices have proliferated in part due to the high price and to the lack of the technological methodologies available to detect them. In fact, the ISO/TS 3632 (2003) the norm that regulates the purity and quality of saffron does not take in account of reliable analytical techniques to detect basic colorants and natural pigments to combat the fraud and to establish objective criteria of quality and food safety. One of the most common fraudulent practices is the use of synthetic colorants and natural pigments. Those products are used in small amounts to dye saffron threads or other plants.Therefore, the Scientific and Technological problem to overcome is the development of cost effective, easy-to-use and reliable methodologies for:1) the identification of fraudulent agents in saffron: synthetic colorants and natural pigments;2) the standardisation of the quality and food safety criteria of saffron.The IAGs and SMEs aim to develop new methodologies to modify the current ISO norm int roducing standards and reliable procedures to fight against the fraud. For this purpose, seven European saffron IAGs and nine SMEs are directly involved in the project. IAGs and SMEs are supported by four RTD performer experts in saffron and 8 independent certified laboratories for the validation of the methodologies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Digital Cultural heritage NETwork - ERA-NET supporting cooperation for research infrastructure in the digital cultural heritage field' (DC-NET).

assistant: **Concept**

The main objective of the DC-NET project is to develop and to strengthen the co-ordination among the European countries of public research programmes in the sector of the digital cultural heritage.  The project will contribute to the integration of the research capacities of the participant member states, will identify their communalities and will valorise existing programmes and projects in order to initiate the deployment of a wide and comprehensive European e-Infrastructure that will increase the research capacities of the digital cultural heritage community.The DC-NET project will contribute to the coordination of coordinate the research priorities of accessing of e-Infrastructures by the Ministries of Culture, their Agencies and other cultural bodies (museums, libraries, archives, audiovisual, archaeological sites, etc.) across Europe in the area of the eInfrastructures targeted to the digital cultural heritage. Eight governments and agencies will agree a set of common priorities for digital cultural heritage research and will work with e-Infrastructures providers to identify how best to carry out this research using the National Research and Education Networks. The project will coordinate the manner in which cultural actors can and should engage with national and European e-Infrastructures to generate innovative services, tools and data sets to support the multidisciplinary research of multidisciplinary communities. A programme of seminars, workshops, meetings and conferences will involve all the relevant stakeholders. A plan of joint activities for e-Infrastructure-enabled research in the sector of digital cultural heritage will be generated and the joint activities will be initiated.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'MEDITERRANEAN RESEARCHERS' NIGHT (2024 AND 2025 EDITIONS)' under Horizon Europe.

assistant: **Concept**

More than 500 million people on three continents are united by the world's largest sea, the Mediterranean. Our strategic geographic location and shared history gives us a common character as well as common challenges. The objective of Mediterranean Researchers' Night - MEDNIGHT is to generate Mediterranean unity, providing awareness about common problems, fostering scientific careers, reinforcing researchers’ commitment and progress, and putting science and scientists at the cornerstone of our future.MEDNIGHT shows the attractiveness and importance of the researchers’ work and professions to the general public, with a focus on young people, carrying out a series of activities framed under the common umbrella of what we have come to call Mediterranean Science, a source of progress and well-being. Mediterranean Science relates to research developed in our territories but also the countless collaborations with other EU researchers. Mediterranean Science is focused on Mediterranean relevant topics according to our culture, way of life or current challenges: History and Heritage, Life and Health, Diet and Nutrition, Sea and Pollution, Climate and Clean Energies, Geology and Biodiversity, Technology and Future.Many online and face-to-face diverse activities will be organised by MEDNIGHT consortium in Messina, Lesvos, Xanthi, Nicosia, Istanbul, Brussels, Monastir, Montpellier, Toulouse, Madrid, Almeria, Orihuela and Tabarca (Main cities) but also Athens, Patras, Limnos, Rhodes, Syros, Eyupsultan, Kadikov, Guardamar, Torrevieja, Santa Pola, Nantes, Larnaca among others.The evolution, expansion and at the same time consolidation of the pillars of MEDNIGHT are being clear, with partners from eight different countries: Spain, Greece, Italy, France, Cyprus, Turkey, Tunisia and Belg
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Sustainable Finance and the News Media' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

On January 31, 2018, the High-Level Expert Group on Sustainable Finance (HLEG) of the European Commission published its final report with recommendations. However, despite recent global movements (e.g., UN Sustainable Development Goals), a broader societal change toward a more sustainable economic system has failed to materialize. One reason is that sustainable finance has not yet become an integral part of today’s (financial) narrative. Researchers in communication science have highlighted the pivotal role of the news media in inducing signs, symbols and meanings to spur interest for certain topics for many years (i.e., agenda-setting). Yet, research on the communication of sustainable finance is, up to now, non-existent. This research project will fill the research gap by investigating the role of the news media in raising public awareness and understanding of sustainable finance, and subsequently, European citizens’ motivation to engage and eventually implement sustainable finance in their daily lives. To do so, a Delphi study among financial journalists in Europe will give insights into role perceptions and gatekeeping processes in editorial offices when reporting on sustainable finance. Furthermore, a large-scale semi-automated content analysis of the coverage of sustainable finance in European financial news over the past 10 years will show how the topic has evolved over time (e.g., actors). Moreover, focus group discussions combined with an experimental survey among European citizens will inform the public about news media framing effects on individual’s attitudes and behavioural intentions vis-à-vis sustainable finance. Concluding, the proposed research project will not only educate financial experts, educators and communication experts on how to successfully co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The symplectic geometry of anti-self-dual Einstein metrics' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

This project is founded on a new formulation of Einstein's equations in dimension 4, which I developed together with my co-authors. This new approach reveals a surprising link between four-dimensional Einstein manifolds and six-dimensional symplectic geometry. My project will exploit this interplay in both directions: using Riemannian geometry to prove results about symplectic manifolds and using symplectic geometry to prove results about Reimannian manifolds.Our new idea is to rewrite Einstein's equations using the language of gauge theory. The fundamental objects are no longer Riemannian metrics, but instead certain connections over a 4-manifold M. A connection A defines a metric g_A via its curvature, analogous to the relationship between the electromagnetic potential and field in Maxwell's theory. The total volume of (M,g_A) is an action S(A) for the theory, whose critical points give Einstein metrics. At the same time, the connection A also determines a symplectic structure \omega_A on an associated 6-manifold Z which fibres over M.My project has two main goals. The first is to classify the symplectic manifolds which arise this way.  Classification of general symplectic 6-manifolds is beyond current techniques of symplectic geometry, making my aims here very ambitious. My second goal is to provide an existence theory both for anti-self-dual Poincaré--Einstein metrics and for minimal surfaces in such manifolds. Again, my aims here go decisively beyond the state of the art. In all of these situations, a fundamental problem is the formation of singularities in degenerating families. What makes new progress possible is the fresh input coming from the symplectic manifold Z. I will combine this with techniques from Riemannian geometry and gauge theory to control the sing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Hybrid SCAlable sparse matrix Linear Algebra for industrial applications' (HYSCALA), addressing dissemination and exploitation.

assistant: **Impact**

HYSCALA will develop a value proposition based on Fraunhofer’s linear algebra library GaspiLS for industrial applications. HYSCALA aims at understanding the customer needs in several industrial application areas starting with the oil and gas segment. We will reach out to strategic customers and build a growing and stable business.GaspiLS is based on the programming interface for parallel applications, GPI-2. As such, GaspiLS incorporates the shift in programming paradigm which is stimulated by the GPI-2 API. This yields an excellent scalability required on modern hardware. HYSCALA strongly relies on this superior scalability and on the interoperability concepts studied in the linke EC-funded INTERTWinE project proving that also legacy applications may safely use a GPI-2 based library. This has removed a major obstacle in the commercialization of GaspiLS.HYSCALA will help to initially promote GaspiLS in the oil and gas industry, our established business segment. We plan to use our existing business contacts as dissemination channels and try to identify potential areas of application and cooperation. The integration of our libraries into existing or new applications will stimulate new developments enhancing GaspiLS and GPI-2. If successful, we will be able to negotiate license agreements with respect to the GaspiLS library and the GPI-2 programming interface. At the end of the FET Innovation Launchpad, the ultimate goal is to establish a market segment for GaspiLS and GPI-2.The uptake of GaspiLS and GPI-2 in industry applications will improve their competitiveness due to a better scalability, performance and elasticity with respect to developments in current and future compute architectures. It will increase the acceptance of the GPI-2 programming model beyond Europe. The