RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'A new polymer electrolyte for increasing the electrode utilisation, energy and power density and reducing charge time in lithium-ion-batteries' (1994-1998) under Fourth Framework.

assistant: **Objectives**

It is the purpose of this research proposal to investigate the use of solid polymer electrolytes with immobilised, charge delocalised anions in lithium-ion batteries and lithium polymer batteries for increasing the current density and electrode utilisation. The research is needed in order to identify the most suitable anions for the task considering charge delocalisation, stability against reduction and oxidation and dissociation of the ion pair. The influence of the composition of the selected anion/polymer systems on ionic conductivity and mechanical properties will be analysed.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Which building blocks for coordinating resource distribution are so basic that they manifest even in infancy?'.

assistant: **Objectives**

COORDINATE will do political psychology with infants to reveal meaningful mechanisms for coordinating resource distribution so basic that they manifest even in the preverbal mind. The distribution of resources, help, territory and priority decision rights are central dilemmas for group-living species and the core of politics. Navigating these dilemmas, young children must discover the structure of their social world: who is friend or foe, superior or subordinate, and what does this mean for how people interact? To solve this learnability problem, I argue that early- and reliably-developing core representations and motives have evolved for navigating basic kinds of social relationships with critical adaptive value. Consistent with this theoretical proposal, I discovered that preverbal human infants mentally represent social dominance and, like other animals, use relative size to predict the outcome of zero-sum conflict, spawning a new field of research (Thomsen et al, 2011, Science). However, human society is also defined by reciprocity and by distributing resources according to need, effort and prior possession, yet it remains unknown if these coordination mechanism are inscribed already in the preverbal mind. Here, we test the high-risk proposals that 1) preverbal infants expect direct reciprocity to govern resource donations; 2) infants and preschoolers use gratitude to predict the future reciprocal altruism of others; 3) infants also use asymmetries of prior possession, hunger need and relative effort to predict who will prevail in resource conflict; 4) that beyond the dyadic and triadic relationships typically studied in the field, preschoolers and preverbal infants use the abstract structural forms of pyramidal hierarchy, clique and lines to represent the group rel
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'A combined experimental and computational approach for quantitative and mechanistic understanding of transcriptional regulation' (2007-2013).

assistant: **Innovation**

The complex functions of a living cell are carried out through the coordinated activity of many genes. Since transcription is a key step in establishing such coordinated activity, much effort was devoted to its study, and tremendous progress was made in identifying many of the transcription factors and regulatory DNA elements involved in the regulation of specific systems. However, very few attempts were made at going beyond these phenomenological and qualitative descriptions. Consequently, we are far from a quantitative and predictive understanding of transcriptional regulation. Through this program, I aim to develop a mechanistic understanding of transcriptional regulation, and for the first time model the entire process. We wish to go much beyond identifying and qualitatively describing the involved components, and arrive at a quantitative understanding of how transcriptional programs are encoded in the DNA sequences. To this end, my team and I will first work to mechanistically understand various building blocks of the transcriptional system, including: mechanisms of activation and repression; binding cooperativity; binding competition; transcription factors and chromatin interplay; architectural features of promoters that are important for its function; and the transcription functions “computed” by promoters. Since existing data are clearly insufficient for addressing such questions, I have opened an experimental lab and began to assemble a multidisciplinary team of scientists whose expertise span the experimental biology, computer science, physics, statistics, and mathematics disciplines, that will work synergistically to generate the appropriate data, analyze it, and use it to construct and experimentally validate models for the above transcriptional building blo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Era bioenergy strategy - short term measures to develop the european research area for bioenergy rtd (target actions : b, h, j)'.

assistant: **Concept**

To reach the goals set by the White Paper" and the "Kyoto Protocol " bio energy RTD will have to be enhanced significantly. The introduction of the European Research Area (ERA) will support this.An Accompanying Measure on actions necessary for the implementation of ERA in the field of bio energy RTD should be carried out with the objectives:- to develop strategies for measures to promote coordination between EU and the member states in the area of bio energy RTD policies and programmes, and- to identify opportunities for short-term actions leading to the ERA for bio energy RTD.The project consists of these tasks:- A "Country survey": Survey of national and EU RTD policies and programmes.- B "Bio energy policies and programmes mapping"."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Prevention of SARS-CoV-2 infection through development and clinical testing of a novel Virus Like Particle (VLP) vaccine' (VLP), addressing dissemination and exploitation.

assistant: **Impact**

Our aim is to perform pre-clinical and clinical evaluation of a potential Wuhan Coronavirus vaccine candidate. The vaccine will be based on Virus-Like Particle (VLP) display of the SARS-CoV-2 Spike protein antigen. AdaptVac's VLP display technology has been shown to significantly improve vaccine immunogenicity, longevity and efficacy, for a wide range of viral and parasite diseases in pre-clinical studies (including flu and malaria). A unique feature of the technology is its two-component approach. The VLP is generic to all vaccines, and produced at >1g/L yields using E. coli. The disease antigen is produced in any expression system, allowing the most challenging antigens to be successfully produced. The VLP and antigen is then simply mixed, and a spontaneous, irreversible, conjugationoccurs under physiological conditions. This results in site-specific, directional, and high-density display of the antigen on the VLP surface. The antigen will be produced using ExpreS2ion's Drosophila S2 insect cells based on the trimetric spike antigen. Furthermore, E. coli and baculovirus will be tested for Spike protein variants. The vaccine candidates will be tested pre-clinically using in vitro viral neutralization assays and possibly animal challengemodels as they become available at LUMC. ExpreS2ion will develop the production processes and transfer these for GMP manufacture of the VLP and vaccine antigen, outsourced, to AGC Biologics. Finally, a phase I/IIa study will be performed at Radboud University Medical Center in the Netherlands. A surrogate marker of protection will be established by showing protection in animal models using passive transfer of participant sera, or by in vitro SARS-CoV-2 viral neutralization. This project is focused on delivering a scalable vaccine, ready
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Upgrading Railways from the Air' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The deployment of advanced signalling systems (ERTMS) in Europe is encountering issues related to the use of manual and obsolete tools. Also, rail maintenance costs are still expensive in terms of effort and safety, and infrastructures lack of flexible systems to ensure security, surveillance and supervision. To resolve these problems, railways digitalisation has become a major trend within the industry.SigmaRail has developed Skylynx, a UAV-based system that aims to address these challenges to support Europe’s transportation investments (ERTMS and Galileo GNSS), by digitalising the Railways. It would add the following values bases on a high skilled and experienced core team:-Geographical data acquisition: Current main line railways need a detailed and accurate survey to capture geographical data, prior to the deployment of ERTMS. Skylynx would reduce by 30% its costs. -Assets maintenance and supervision: Equipment placed along the main line tracks in Europe are highly prone to suffer from maintenance issues. Each unpredicted failure is capable of causing service delays, as well as affecting travellers’ safety. Skylynx shall reduce costs, increasing by 15% trains frequency.-Safety: All the above tasks require workers to access the track four-foot. Skylynx, thanks to its UAV-based technology, will avoid this, increasing safety.-Security: Skylynx final deployment would ensure the control of the railway corridor access, capturing specific details and enabling expert evaluation of the railway status and access control.Thus, Skylynx is an innovative tool for railway lifecycle management, composed by UAVs equipped with sensors, nesting platforms, back-end processing nodes and a rail assets recognition software that will offer geographic information, maintenance, supervision a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Ecosystem Modelling of Biospheric Responses to Anomalous Climate Events with Sun-Induced Fluorescence' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Heatwaves and droughts, intensified by climate change, pose a significant threat to European ecosystems, reducing gross primary productivity (GPP) and disrupting the global carbon cycle. The EMBRACE-SIF project seeks to improve the predictive accuracy of sun-induced fluorescence (SIF)-enabled terrestrial biosphere models (TBMs) under stress conditions. Currently, models like ORCHIDEE struggle to capture the photosynthetic response during extreme events due to limitations in modeling photosynthesis and characterizing non-photochemical quenching (NPQ). To overcome these challenges, the project will implement the Johnson and Berry (J&B) photosynthesis model, which provides a mechanistic framework for electron transport rates (ETR), and extend it to better represent NPQ under heat and drought stress. Using the unique Austro-SIF dataset and assimilating canopy-scale SIF and GPP data, EMBRACE-SIF will optimize key parameters in ORCHIDEE, enhancing its ability to simulate GPP during past European heatwaves (e.g., 2003, 2010, 2018, 2022) and at a global scale. The project's results will improve GPP predictions, contributing to climate resilience and supporting the European Green Deal's target of achieving carbon neutrality by 2050. Additionally, it will strengthen the fellow's expertise in remote sensing and biosphere modeling, positioning them for leadership in these critical fields.


**Keywords:** Sun-Induced Fluorescence, Terrestrial Biosphere models, photosynthesis, non-photochemical quenching, gross primary production, heat wave, extreme events, ORCHIDEE
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Improved Rheological Characterisation of Ceramic Slips and Glazes Using Zeta Potential' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

The ceramic industry depends on the use and control of a wide variety of clay and mineral suspensions in water for most forming processes. The consistency, stability and predictability of these aqueous suspensions are crucial to the successful manufacture of ceramic articles and minimising losses.Currently the industry uses simple measurements of density and fluidity to determine the suspension properties and the addition of deflocculants, flocculants etc. to control their behaviour in production. The problem is that even though these suspension properties can be measured accurately and controlled within specified limits, many suspensions still exhibit anomalous behaviour during the making process leading to unacceptable production losses. There is an urgent need, therefore, for a method of characterising these suspensions such that their performance in the various forming processes can be assured.To gather sufficient background information relating to zeta potential (a measure of the stability of a suspension) and ceramic suspensions to:* Improve the efficiency of ceramic suspension and so production control;* Improve the control of glaze materials so ensuring consistent high quality glaze applications;* Allow the forming characteristics of clay suspensions to be predicted and controlled.This will allow the following industrial objectives to be met;* Improve the efficiency and productivity of ceramic manufacture;* Reduce the rework of suspensions which are within specification but unsuitable for use;* Reduce wastage of toxic ceramic materials.Start meeting held 12th March 1998 confirmed objectives and work programme. Selection, preparation and supply of base materials commenced.Ceramic raw materials used in body slips and glaze suspensions will be investigated by tradi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'New vaccine for a paradigm shift in Brucellosis'.

assistant: **Concept**

Brucellosis is consistently ranked as the world’s most common and widespread zoonotic disease, meaning that it normally exists in animals but it can also infect humans. In livestock, it causes devastating production losses in low-income countries accounting in more than €3bn per year. In humans, there are 500,000 new cases annually requiring long-term hospital treatments.Brucellosis is endemic in most Asia, Africa and LATAM and is prevalent in the EU Mediterranean regions. Also, outbreaks may take place anywhere in a global world with international trading, people travelling all around the world and potential threat of bioterrorism.Since human vaccines are not available, the most rational approach for preventing human brucellosis is the control and eradication of infection in animals. Animal vaccines are an essential tool, but existing vaccines own some inconveniences, such as residual virulence, complex management systems and costly diagnostic techniques that are not appropriate for developing countries; in Europe, control programs are based in tests for animal check-ups and compensation to farmers for slaughter of the infected animals, with vaccination prohibited or highly restricted to areas with higher prevalence of Brucellosis. These inconveniences recommended the development of new candidate vaccines. We are developing BGV1, a patented vaccine that has the potential of allowing, for the first time, mass vaccination of any animal at any time (including pregnant and lactating animals), which is a radical paradigm shift in Brucellosis control and eradication. It also simplifies existing vaccine management systems as it can be used without interfering standard diagnostic techniques. In our 5-year forecast, we estimate accumulated revenue and net profits of €58.29m and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Financial Intermediation of Long-Term Savings' under Horizon 2020.

assistant: **Concept**

Against a backdrop of population aging and secular decline in interest rates, traditional state and occupational pension systems are under stress, forcing households to increasingly rely on their own savings and to bear financial markets risk. Financial intermediaries increasingly take up the role of collecting and investing households’ long-term savings. In the EU, household savings intermediated by life insurers amount to 8 trillion euros or 22% of aggregate household financial wealth. Moreover, life insurers are not pass-through intermediaries: They actively provide households with insurance against market risk through intergenerational risk sharing mechanisms and return guarantees.I will use a combination of unique regulatory data, empirical designs grounded in theory (existing and that I will develop), and careful identification strategies, to understand the role of life insurers in intermediating households’ long-term savings and providing them with insurance against financial markets risk. I will study how savings products embedding such insurance share aggregate risk between households and intermediaries, and between different cohorts of households. I will analyze the impact of these risk sharing arrangements on the supply of capital to the real economy. I will assess the impact of competition between financial intermediaries and the impact of capital constraints on the provision of insurance against aggregate risk and on the build-up of systemic risk in the insurance sector. On the way, I expect to contribute to the policy debates on the financing of retirement and the regulation of financial intermediaries.


**Keywords:** Long-tem savings,  European life insurers,  Intergenerational risk sharing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Synthesis of combinatorial libraries of vinylogous sulfonopeptides' (1994-1998).

assistant: **Innovation**

In the context of isosteric replacement of the peptide bond it seems very interesting to synthesize pseudopeptides characterized by the presence of sulfonamide bond. This modification gives important properties to sulfonamidopeptides and makes them pro- mising candidates in the development of protease inhibitors and new drugs. The development of a combinatorial library of viny- logous sulfonopeptides will be specially interesting due to its great pharmaceutical potential. The aim of this project is to synthesize vinylogous sulfonopep- tides and combinatorial libraries with them. It includes three steps: a) Synthesis of the functionalized monomers (vinylogous a- minosulfonic acids) like the derivatives of Ser. Thr, Asn, Gln, Lys, Met, Trp. b) Optimization of the coupling yields of the monomers and the development of solid phase synthesis method. c) Combinatorial library synthesis both on solid support and in solution. Part of the solid supported combinatorial library will be sponsored by Pharmacia" (the Swedish-Italian Multinational Pharmaceutical Company). This Multinational will also test the sulfonopeptide libraries for biological and pharmacological activity. "
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Allosteric modulation of adenosine reseptors. a novel concept of receptor activation and inhibition' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Alistair modulation of G protein-coupled receptors is a novel concept in receptor pharmacology. In this project a combined chemical/biological approach will be followed to design novel allotter modulators of adenosine receptors. These compounds will then be used to try and identify receptor amino acids that are involved in their binding.