RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Towards off flavour free finfish aquaculture' (SPACETASTE) targeting Seventh Framework.

assistant: **Abstract**

Off flavour is the presence of undesired sensory properties in food items. Most common in aquaculture products are earthy-musty off flavours caused by the presence of geosmin and 2-methyl-iso-borneol (MIB) in fish tissues. Off flavour is associated to land-based aquaculture production systems with high nutrient loadings such as pond systems and recirculating aquaculture systems (RAS).Off flavour causes economic damage to the aquaculture industry through consumer rejection and low consumer appreciation of aquaculture products and through the additional costs of off flavour removal from fish crops prior to market entrance. Off flavour in farmed fish is an extensively studied and well documented problem. Despite this, satisfactory solutions for the problem are still lacking today. The overall objective of this project is to established a reduction of the incidence of off flavour in farmed fish produced in RAS. The project adopts three strategies to reach this objective:1) Preventive strategy: reducing the microbial production of geosmin and MIB in aquaculture production systems;2) Curative strategy: removing geosmin and MIB from the fish culture water;3) Alternative strategy: optimizing the depuration process.The foreseen results of the project include:1) Measures to reduce off flavour in RAS2) Low off flavour RAS design3) A bioreactor for geosmin and MIB removal from RAS4) Measures to improve off flavour depuration processes5) Design of optimal off flavour depuration facility6) Trained sensory panelsThe consortium that will implement this project consists of four SMEs, one Other partner and three RTDs.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Structural ceramic nanocomposites for top-end functional applications' under Sixth Framework.

assistant: **Concept**

Many new technological advances are limited by the impossibility to combine high mechanical performances of actually known ceramic materials with critical functional or structural material properties. The objective of this Integrated Project (IP) is to pr ovide and industrialize knowledge-based nanoceramics (<100nm) and nanocomposites (second phases <10 nm) for top-end functional and structural applications that are beyond reach with incremental materials development only. Nanocomposites" entirely made up ceramic and metallic nanoscale particles or nanoscale phases, denote a broad, new class of engineered materials where unique and otherwise unattainable properties can be revealed. The industrial applications of nanocomposites rely on the successful consolidation of these materials into bulk-sized components while preserving their nanostructures. Traditional consolidation techniques have strong limitations of not being able to retain the nanoscale grain size. The technological objectives and expect ed breakthroughs of IP NANOKER will consist of: New multifunctional materials with hardness, fracture resistance and fracture toughness properties up to 2-3times higher than the best state-of-the-art materials that operate in chemical-physically aggressi ve environments. New multifunctional materials processed into knowledge-based, industrially applicable nanoceramics and nanocomposites with added multifunctionalitv, e.g. biocompatible functions and very long lifetime, optical properties and biocompatibl e functions, tribochemical functions and excellent electrical conductivity, nanocoatings with tribological and barrier functions, etc. The multi-sectorial and cross-cutting approach of this IP is the only mean to assemble the critical mass needed to break through these roadbl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Promoting a functional and comparative understanding of the conifer genome- implementing applied aspects for more productive and adapted forests'.

assistant: **Innovation**

In the midst of a climatic change scenario, the genetics of adaptive response in conifers becomes essential to ensure a sustainable management of genetic resources and an effective breeding.  Conifers are the target of major tree breeding efforts worldwide.  Advances in molecular technologies, such as next-generation DNA sequencing technologies, could have an enormous impact on the rate of progress and achievements made by tree breeding programmes. These new technologies might be used not only to improve our understanding of fundamental conifer biology, but also to address practical problems for the forest industry as well as problems related to the adaptation and management of conifer forests. In this context, ProCoGen will address genome sequencing of two keystone European conifer species. Genome re-sequencing approaches will be used to obtain two reference pine genomes. Comparative genomics and genetic diversity will be closely integrated and linked to targeted functional genomics investigations to identify genes and gene networks that efficiently help to develop or enhance applications related to forest productivity, forest stewardship in response to environmental change or conservation efforts. The development of high-throughput genotyping tools will produce an array of pre-breeding tools to be implemented in forest tree breeding programmes. ProCoGen will also develop comparative studies based on orthologous sequences, genes and markers, which will allow guiding re-sequencing initiatives and exploiting the research accumulated on each of the species under consideration to accelerate the use of genomic tools in diverse species. ProCoGen will integrate fragmented activities developed by European research groups involved in several ongoing international conifer genome
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Embedding catalysts in liquid wall flow devices' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Flow reactors offer benefits over batch reactions, such as precise control over conditions  and high turnover numbers of catalysts through immobilization in packed beds. However, the small dimensions of the flow reactor lead to increased friction between solvent and reactor wall, which causes loss in efficiency. In addition, flow systems are vulnerable to reagents that may foul or clog the system. The host group recently developed microfluidic tubes with ferrofluid walls. The walls are kept in place by a quadrupolar arrangement of magnets, while their liquid nature diminishes the friction at the interface and prevents particles from clogging the system by temporarily expanding the microtube when necessary. In this project, I intend to improve on this system by embedding well-established catalysts immobilized on magnetite nanoparticles into the ferrofluid. This will allow us to achieve the high turnover numbers that are common for flow reactors containing immobilized catalysts, while benefiting from the low-friction and anti-clogging properties of the liquid wall tubes. In addition, I will perform mechanistic analysis of the newly developed flow reactions in liquid wall tubes. This will aid the broader scientific community to further expand the utility of this new technology. As such, the project promises important improvements in the field of flow chemistry. The highly interdisciplinary nature of the project allows me to fully apply my expertise in the field of catalysis, while benefiting from knowledge transfer in microfluidics, in which the host research group has an expertise.


**Keywords:** flow chemistry, microfluidics, magnetic nanoparticles
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Proof complexity of circuit lower bounds' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

One of the most fundamental and notorious open problems in theoretical computer science is the possible existence of highly efficient algorithms solving NP problems: there might be fast algorithms breaking established cryptosystems, automating theorem proving, making contemporary approaches to AI obsolete, and solving practically every computational task. This issue lies at the heart of the P versus NP problem, a central question of computational complexity, and particularly in the investigation of lower bounds on the efficiency of concrete computational models such as Boolean circuits.The notorious difficulty of proving complexity lower bounds became evident already in the early days of the theory of computing when the theory of formal barriers explaining their difficulty started to emerge. In recent years, there has been a dramatic rise of barrier results driving the field forward and connecting it to areas such as learning theory and cryptography. A better understanding of formal barriers is emerging today as the necessary requirement for further progress on central problems in computational complexity, and the goal of this project is to develop a systematic theory around it: proof complexity of circuit lower bounds. In particular, the project will bridge the rich tradition of concrete combinatorial methods with the new meta-mathematical approach via the phenomena of hardness magnification that connect strong and weak computational models. It will focus on a logic-oriented area of proof complexity investigating the lengths of propositional proofs and use its meta-mathematical perspective to explore the potential of lower bound methods in circuit complexity but also in proof complexity itself.The proposed meta-mathematical approach presents a novel perspective on esta
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Retrieval of multimedia Semantic units for enhanced reusability' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

The overall aim of RUSHES is to design, implement, validate, and trial a system for both delivery of and access to raw media material (rushes), as well as its reuse in the production of new multimedia assets. RUSHES targets indexing, search and retrieval of rushes archives, to ease in-house postproduction and reuse in a professional environment. It also aims at providing raw content to end users for the creation and editing of content in a shared computational environment using a multimodal approach that combines knowledge extracted from the original content, metadata, visualization and interactive browsing functionality.RUSHES will consider professional content creator or provider, and consumer for the design of the system. At the provider side, techniques for automatic content cataloguing and semantic based indexing will be used to link raw content with metadata. At the consumer side, browsing and retrieval strategies will be implemented to provide advanced search functionalities and low access latency when navigating rushes databases. The core research issues of RUSHES are knowledge extraction for semantic inference, semantic-based content annotation, scalable multimedia cataloguing, interactive navigation, and non-linear querying and retrieval techniques using hierarchic descriptors.To evidence the viability of the project goals, a complete system for search, retrieval and use of rushes will be designed, implemented and tested with potential professional and end-users. The envisaged system prototype will not only serve as a means to showcase the functionality of the proposed technology but also provide a realistic and commercially valid proof of concept.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Cancer control using populationbased registries and biobanks'.

assistant: **Concept**

Longitudinal studies nested in biobanks enable more reliable and efficient study designs for molecular epidemiology studies, both for design and evaluation of cancer treatment and cancer prevention as well as for exploring and evaluating etiologic hypotheses. However, several prerequisites apply:-There must exist very large scale biobanks who should already have several decades of follow-up.-It must be possible to link biobanks with quality-assured population-based cancer registries to enable population-representative studies with minimal case ascertainment bias.-Important problems regarding overview, accessibility, quality control, phenotypic characterisation, efficiency and avoiding risks for violation of personal integrity must be addressed.The present network has joined large biobänks with up to 30 years of follow-up and >60.000 prospectively occurring cancer cases and cancer registries with >40 years of population-based registration, to achieve the following goals:1. Provide the study base for uniquely large population-based prospective studies on cancer.2. Define and implement a European Quality Standard for Biobanking.3. Define and promote the implementation of integrity-proof methods for biobank-based research involving well defined and secure third party code-keeping systems.4. Enable large-scale, population-based research on:a) evaluation of cancer treatment and role of molecular markers in treatment selection;b) identification and evaluation of genetic markers associated with increased cancer risk using over-generation linkages;c) exploration and evaluation of intrauterine exposures associated with increased cancer risk using over- generation linkages;d) design of optimal strategies for cancer prevention and its evaluation.5. Establish a Europe-wide network f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Waste to recovered fuel' (TBR).

assistant: **Innovation**

It is intended to facilitate a cost-effective system for integrated resource and waste management which will reduce costs for both the waste management and power generation industries, and the end consumer. The objective is to bring together relevant stakeholders within a discussion Forum that will adopt an informed technical and economic position on waste recovery in general, and on the production and use of solid Recovered Fuels in particular. Debate in the Forum will be informed through the compilation of a database of existing plant performance and emissions data, collected from operational projects across the EU. Information from the database will be used in an economic and environmental cost/benefit analysis on alternative recovery and disposal routes. Model quality systems for the production of solid Recovered Fuels will also be generated, together with a work programme (for the drafting of European Standards) that could be adopted by CEN in a Technical Committee.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Boost Brittle Bones Before Birth'.

assistant: **Objectives**

Osteogenesis imperfecta (OI) is, in its severe forms, a devastating inherited disorder characterised by brittle bones. A person with severe OI is affected throughout their lifetime with repeated, multiple fractures, considerable pain and handicap. There is no curative or effective treatment for OI. Our preclinical studies and initial clinical cases have demonstrated that transplantation of fetal mesenchymal stem cells (MSC) is a promising approach for treatment of OI. We receive regular requests for MSC transplantation from patients and their physicians; patient organisations support our approach.The principal objective of the BOOSTB4 project is to conduct a Phase I/II clinical trial of the safety and efficacy of pre- and/or postnatal MSC transplantation in the severest forms of OI (type III, severe type IV). Transplantation before birth at the onset of disease should lead to greater efficacy and engraftment with less rejection than transplantation after birth. Postnatal transplantation will be evaluated in cases where prenatal diagnosis was not made. The trial’s primary outcome is safety; secondary outcomes relate to efficacy (fracture frequency, growth, bone mineral density and quality of life). All patients will undergo molecular diagnosis to confirm OI before inclusion in the trial. Non-invasive prenatal diagnosis will be developed and validated. The BOOSTB4 consortium is led by experts in MSC, prenatal therapy and OI at the Karolinska Institutet (KI), which will also lead the international multicentre trial; five additional EU centres of excellence are included. Ethical and regulatory applications are underway to conduct this clinical trial. These are facilitated by the ethical and regulatory approvals for prenatal MSC transplantation in 10 cases of OI that have al
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'A hydraulic collection tower, with a novel energy storage device for wave energy arrays'.

assistant: **Objectives**

Wave energy convertors (WEC) capture the energy contained in ocean waves and use it to generate electricity. The use of wave energy provides the opportunity to generate energy at a wide range of locations throughout Europe, which will strengthen the stability of Europe’s energy networks. WEC developers have still not achieved a lower cost of energy through a viable and competitive technology.  Ocean Harvesting Technologies AB (OHT) was founded in 2007 and develops an innovative and patented hydraulic collection system and storage technology for wave energy arrays. The power captured by wave energy converters (WEC) is pumped in the form of pressurized fluid through a piping system to a central tower, where the collected power is first smoothed by the novel OH energy storage device and then converted into electricity. OHTs vision is that their technology will solve the problems with current centralized hydraulic collection systems through a more efficient solution and ultimately lead to lower cost of energy. Besides generating efficient and even power, the simplicity of the OH design will allow better protection in rough conditions, and make its manufacture impressively cost-efficient. OHTs energy storage technology will not only remove the intermittent nature of wave energy but turn wave farms into flexible power plants. OHT have raised 3,2 M EUR in private equity to date.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The evolutionary genetics of multidimensional plasticity in a wild seabird' under Horizon 2020.

assistant: **Concept**

PLASTIC TERN is an interdisciplinary project using an ecological and evolutionary framework to integrate the study of physiological, behavioural and life-history traits to elucidate multi-dimensional patterns of phenotypic plasticity in the wild. We will focus on the evolutionary genetics of plasticity in a natural population of a relatively long-lived seabird under long-term investigation, the common tern (Sterna hirundo). More specifically, we will investigate how genetic variation in, and selection on, plasticity are shaped by internal factors, such as age, and external factors, such as temperature, breeding density and food availability; we will be using multiple labile traits (annual number of fledglings, body mass and spatial colony use) and studying multiple levels of variation. The long-lived nature of our study species and the natural annual fluctuations of food availability, temperature and density that characterise the study area and population provide a unique opportunity to study plastic responses driven simultaneously by intrinsic factors, such as age, and/or ecological factors. Additionally, the exceptional dataset collected on this population allows us to study how selection (via annual survival and reproductive success, as well as Lifetime Reproductive Success) acts on the previously described plastic responses. Despite the explicit evolutionary relevance of the question, the consequences of environmental changes for the action of natural selection on plasticity have remained largely unexplored.