RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Stable isotopes and Mediterranean ARidification: Tree Rings in Ecological and Environmental Studies' (SMARTREES), addressing dissemination and exploitation.

assistant: **Impact**

Global climate change, combined with the further increase of atmospheric CO2, is expected to affect plant growth and performance and, as a consequence, the spatial distribution of species in terrestrial ecosystems within the next 50 to 100 years. In the Mediterranean region, the combined impact of current aridity with climate change will particularly threaten forest ecosystems. In addition, global change is likely to impact carbon sequestration in the forest sector, and trade-offs between mitigation and adaptation measures may arise in the future. Thus, a proper use of genetic material for reforestation (one of the main mitigation options in European forestry) is crucial to face new climate circumstances at an early stage through anticipatory adaptation. In this regard, there is a need to understand long-term plant responses to climate changes in order to define the most appropriate adaptation measures. Tree rings provide an easily datable archive that can be explored for physiologically relevant signals. In particular, the analysis of carbon and oxygen stable isotopes in tree-rings combines the ability to integrate physiological information over different time scales, which allows validating the results over a great number of sites. However, although the basic principles for carbon and oxygen isotopes in plants are well known, there are still some unsolved questions. The general objective of the proposal is to explore and further develop the application of stable isotopes in Mediterranean pines as ecophysiological tools. This will involve 1) basic research to better understand the underlying mechanisms determining stable isotope composition in trees and their relationship with physiological processes, and 2) applied research to develop the use of stable isotopes as too
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Public Policy, market organization and transition economies' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

The aim of this training project is to prepare students for careers in teaching, research or government services and to prepare researchers for active participation in the analysis of the fundamental economic questions facing mixed-market regulated and tra nsition economies. The programme is designed to ensure that students acquire rigorous and state of the art knowledge of core areas of economic theory and research methodology and to offer them research opportunities under close supervision. Instead of sett ing out the theory in an abstract mathematical way, we believe that there is a strong case for reversing the usual order by conveying the concepts of economic theory through the medium of their use and application market regulation and to the problem faced by formerly centrally-planned economies in their transition to the market economy. The proposed project will provide state-of-the-art training in the fields of public policy, industrial organization and transition economics. These fields of modern econom ics are complementary and closely related in several respects. In particular they enjoy a dual status of leading economic fields from an academic point of view and of important sources of guidance for key public policy issues into one of the most interest ing and important areas of economic transition in the world. In addition, their reliance on the same advanced methodology is one of the contributing factors to their suitability for joint advanced training. The fields under consideration provide the intell ectual background and expertise for effective decision-making in such critical areas of public policy as industrial policy, antitrust, regulation, taxation, labor market programs, economic decentralization, and institutional design of transition economies. By p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Neutron Scattering and Muon Spectroscopy Integrated Initiative' to be submitted under Seventh Framework.

assistant: **Abstract**

Advanced solutions to the challenges that confront our technology-based society – from energy and environment to health – are crucially dependent on advanced knowledge of material properties down to the atomic scale. Neutron and Muon spectroscopy offer unique analytical tools for material investigation. They are thus an indispensible building block of the European Research Area and directly address the objectives of the Innovation Union Flagship Initiative. The knowledge creation via neutron and muon spectroscopy relies on the performance of a closely interdependent eco-system comprising large-scale facilities and academic and industrial users.The Integrated Infrastructure Initiative for Neutron and Muon Spectroscopy (NMI3) aims at a pan-European integration of the main actors within this eco-system. The NMI3 coordination effort will render public investment more efficient by harmonizing and reinforcing the services provided to the user community. It will thus directly contribute to maintaining Europe’s world-leading position.NMI3 is a comprehensive consortium of 18 partners from 11 different countries that includes all major providers of neutrons and muons in Europe. NMI3 exploits all tools available within I3s to realize its objectives.-       Transnational Open Access will build further capacity for European users. It will foster mobility and improve the overall creation of scientific knowledge by providing the best researchers with the opportunity to use the most adapted infrastructures.-       Joint Research activities will create synergies in innovative instrument development that will feed directly into improved and more efficient provision of services to the users.-       Networking activities will reinforce integration by harmonizing procedures, setting standar
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Engineering of biomimetic surfaces: Switchable micropatterns for controlled adhesion and touch' under Seventh Framework.

assistant: **Concept**

Nature has, in the course of evolution, found many fascinating solutions to “engineering problems”. The proposed work aims at three-dimensional (3D) surface structures inspired by insects, spiders and geckoes. Based on the PI’s earlier work on passive structures, the new challenge addressed by this interdisciplinary project is to design and investigate active, switchable 3D micropatterns, whose adhesion and touch can be tuned at will and modified on demand. The resulting features will bend or tilt in response to external stimuli (especially temperature, electric field and stress) and thereby create a responsive surface structure. Theoretical modelling and simulation of the relevant mechanics will be a major effort to establish “structure-property relationships” for switchable patterned surfaces, to guide the choice of structure parameters and to establish new multifunctional design rules for targeted applications. Emphasis will be placed on the novel aspect of interaction with soft, compliant objects, with a view to creating future opportunities for interaction with soft matter and skin. Talented junior scientists – with both experimental and theoretical background - will be heavily involved as an opportunity to promote their career opportunities in this modern field of materials research. A final objective will be the exploration of the transferability of patterning techniques to larger-scale areas. Overall, such switchable micropatterns will likely open up revolutionary new possibilities in various technologies: robotic grippers with careful, benign “touch” of delicate objects, medical adhesives that become sticky on reaching body temperature, and active devices that can respond and send signals to touching fingers. The successful project will thus lay the scientific
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Investigating the neural mechanisms of feature-based and spatial attention in a network model of two coupled brain areas' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Attention is the ability to focus the processing resources of the brain onto relevant sensory information. This cognitive ability allows us to perceive attended aspects of the environment with enormous precision without being overwhelmed by irrelevant information. Recordings from neurons in the cortex of monkeys performing attentional tasks have demonstrated attentional modulation of sensory neurons in attend-to-location and attend-to-feature tasks (“spatial” and “feature-based” attention). The neural activity in sensory areas is not only modulated by attentional top-down signals but also by sensory-driven bottom-up processes such as neural adaptation. Despite extensive research on these phenomena, an explanation of attention at the level of single neurons and neural networks has remained elusive. The goal of the proposed project is to integrate bottom-up and top-down processes in a computational model in order to progress in the mechanistic understanding of visual attention. We propose using a multidisciplinary approach, based on a tight interaction of modeling and experiment. Experimental data from direction selective neurons of the visual cortex, which have been recorded by our collaborators, will guide the development of a biophysical network model and the model will, in turn, facilitate the data analysis. The model will consist of two cortical areas, one devoted to the active maintenance of information (working memory circuit in prefrontal or parietal cortex) and the other one responsive to novel stimuli (visual cortex, endowed with adaptation mechanisms). We expect the model to clarify the contribution to attentional modulation of interactions within and across cortical areas. In particular, we aim to investigate (1) the underlying mechanisms of bottom-up and top-
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Cost effective Direct to Eye prosthesis SMART Guidance System' in the context of a Seventh Framework call.

assistant: **Objectives**

Approximately 800,000 hip operations are performed annually in Europe. In 56% of these operations, the components, in particular the cup, are not aligned correctly; this misalignment alters the biomechanics of the system, such that excessive wear of the cup occurs. The subsequent reduction in implant lifespan will affect ~450,000 European citizens, an average of 30,000 per year. In financial terms, the annual cost to European healthcare institutes is in the region of €426m euros, in addition to the increased likelihood of re-revision and associated aftercare costs.There are two types of navigation system currently on the market: (1) Image based which uses CT data to generate 3D preoperative images, and (2) Image-free systems which rely on kinematic data or point-clouds acquired intra-operatively to generate a 3D reconstruction that can be explored during the operation on a computer screen. Both systems have demonstrated improved accuracy over manual surgery. However, current systems entail a large initial cost (~€250K) with high maintenance costs; in addition, most systems take an extra 15 minutes to setup, using valuable theatre time.The D2Eye project will develop a simple to use, low cost, fully mobile guidance system with reduced set up time. The guidance system will allow the surgeon to position the cup accurately allowing for optimum range of movement and as a result will prevent premature failure of the implant normally associated with misalignment. This will be done using a series of electronic orientation units built in to the surgical instruments which will give their position in free space. The information from the units will be projected in front of the surgeon’s eye in real time, allowing them to identify the correct cup implantation position; such a system
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Positivity in Lie groups and representation varieties' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Lie groups lie at the heart of mathematics. They play an important role in geometry, analysis, number theory, algebraic geometry and representation theory. As they describe symmetries of a space or a system they also appear prominently in theoretical physics. Not every system realizes the full amount of symmetry, it is therefore of key importance to investigate not only Lie groups, but also their subgroups, and in particular their discrete subgroups, which are often linked to geometric or arithmetic structures.This projects builds upon new developments in the theory of Lie groups, in particular the intro- duction of total positivity in split real Lie groups on the one hand and new exiciting phenomena in the study of discrete subgroups, in particular the emergence of higher Teichmüller spaces.Higher Teichmüller spaces generalize the classical theory of Fricke-Teichmüller space in the context of simple Lie groups of higher rank. The existence of higher Teichmu ̈ller spaces came as a surprise, and their discovery and investigation led to various other interesting developments, including an exciting interplay with the theory of Higgs bundles as well as with supersymmetric field theories in theoretical physics.In this proposal we develop a unifying framework for higher Teichmüller spaces, which comprises the two known families, Hitchin components and maximal representations, but conjecturally also two new families. The basis for this conjectural unified theory lies in a new notion of positivity in Lie groups, which generalizes Lusztig’s total positivity in the context of arbitrary real Lie groups that are not necessarily split. This generalization of total positivity is of interest in its own right and leads to many exciting questions and conjectures that will be addressed i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The Culture of Algorithmic Models: Advancing the Historical Epistemology of Artificial Intelligence' (AIMODELS) targeting Horizon Europe.

assistant: **Abstract**

The project proposes an alternative epistemology of artificial intelligence (AI). It argues that what is at stake in AI is not its similarity to human rationality (anthropomorphism), but its epistemic difference. Rather than speculating in the abstract on whether a machine can think, the project addresses a historical question: What is the logical and technical form of the current paradigm of AI, machine learning, and what is its origin? The project traces the origins of machine learning back to the invention of algorithmic modelling (more precisely, algorithmic statistical modelling) that took shape in the artificial neural networks research of the mid 1950s, and records that a coherent history and epistemology of this groundbreaking artefact is still missing. The project pursues three objectives to turn its findings into a constructive paradigm: 1) a new history of AI that stresses the key role of algorithmic models in the evolution of statistics, computer science, artificial neural networks, and machine learning; 2) a new epistemology of AI that engages with the psychology of learning and the historical epistemology of science and technology; 3) a study of the impact of the large multi-purpose models (e.g. Bert, GPT-3, Codex and other recent foundation models) on work automation, data governance, and digital culture. Through consolidating a model theory of AI, the research will benefit the reception of AI in general and fields such as digital humanities, scientific computing, robotics, and AI ethics, among others. Ultimately, it will help situate AI in the global horizon of the current technosphere and in the long history of knowledge systems.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'CHARTING THE TOKEN OF TIME: YAP/TAZ TRANSCRIPTIONAL REGULATORS AT THE ROOTS OF AGING' under Horizon Europe.

assistant: **Concept**

A major challenge in aging research is to distinguish which age-related alterations play a driving role and their interconnections. Aging ultimately implies dysregulated transcription; yet, the identity of signaling cascades and transcription factors that control youthfulness and aging in adult tissues remains poorly understood. Aging also entails maladaptive changes in how cells communicate with each other and their surrounding extracellular matrix (ECM). Senolytics approaches have revealed the role of senescent cells as drivers of aging, leaving however unclear what cell types first become senescent in real tissue and why.  Here, we aim to address and connect these fundamental unknowns into an integrative view of aging at an unprecedented spatial, temporal, molecular and mechanistic resolution.As preliminary results, we report that aging requires decreased activity of YAP/TAZ mechanosensors in stromal cells leading to unscheduled activation of cGAS/STING signaling, and that aging may be halted by restoring a youthful YAP/TAZ-cGAS/STING signaling balance. But why do we age then? Building on these findings, our hypothesis is that aging initiates from deterioration of our own “structural frames”: from changes in spatial/contextual signals that cells perceive from the ECM, to altered mechanotransduction and increased fragility of the nuclear envelope leading to cell senescence. These processes are reversible and understanding them may reveal new routes to halt aging. For this we will chart and functionally interrogate a multidimensional atlas of aging biology, delving into the logics of tissue physiology and its progressive degeneration over lifetime, also implementing novel methodologies. Our YAP/TAZ prism offers a unique vantage point to dissect causally relevant extrac
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Million-core Molecular Simulation', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Molecular simulation has become a standard tool for studying the function of biomolecules, such as proteins, nucleic acids and lipids. Due to increasing computer power and decreasing length scales in engineering, molecular simulation is also increasingly used in microfluidics and the study of, for instance, small water droplets. All these applications would benefit strongly from simulations that are several orders of magnitude longer than the current state of art. Although currently Moore's law still holds, the performance of processor cores no longer doubles every 18 months, but rather the number of cores increases. Therefore to improve the performance and to scale to a million cores, each core should do less work. With the classical single-program multiple-data parallelism the communication time will quickly become a bottleneck. To advance the molecular simulation field and efficiently use upcoming million core computers, a switch to multiple-program multiple-data parallelism (MPMD) is required. Domain decomposition should be applied over the nodes, whereas within a node MPMD parallelism should be used. This requires workloads being divided and dispatched efficiently to different threads. To hide the communication times, calculation should be overlapped with communication. Because simulation time steps will soon take in the order of 100 microseconds, global communication will become a bottleneck. However,global communication is required for, among other things, full electrostatics algorithms. Thus new algorithms need to be derived to ensure parallel scaling. Only with such efforts we will be able to fully utilize the potential of upcoming hardware to solve current and future scientific problems.