RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Scalable Mapping of Tumor Microenvironment Inspired by Geographic Information System', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Nonmutational epigenetic reprogramming and genome instability are hallmarks of cancer, intricately tied to the tumor microenvironment. Understanding these processes requires scalable, spatially resolved tools at the molecular, cellular, and histological levels. The purpose of spatial omics, similar to geographic information systems (GIS), is to enable the analysis of spatial relationships across complex biological features. In GIS, geospatial indexing allows us to effortlessly search for patterns and events—such as Dating Apps, Chat Apps or Proximity searches (Uber, Lyft, Yelp, Google)—using real-time updates and interactive maps. In contrast, current spatial omics technologies lack scalability, real-time integration, and interactive visualization. Scalable mapping of the tumor microenvironment at multiple levels is essential to decipher tumor progression and identify new therapeutic targets. Inspired by geospatial indexing, I will develop an interdisciplinary toolbox, ScaleMAP, for mapping single-cell spatial epigenetics and genomics within the tumor microenvironment. ScaleMAP offers high-throughput, high-resolution, scalable, and interactive mapping across large tissue sections. 3D reconstruction of ScaleMAP will enable the investigation of cancer evolution in three dimensions. Like Google Maps, ScaleMAP treats tissues as ""biological terrains,"" allowing researchers to interactively zoom into specific areas of interest across molecular, cellular, and histological levels to extract valuable insights. We will also develop GIS-inspired analytical packages for ScaleMAP data. Furthermore, we will adapt ScaleMAP for formalin-fixed paraffin-embedded samples and apply it to clinically archived paired primary and metastatic colorectal cancer samples to dissect metastasis. Bey
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'UMDM: Uniform Management of Data and Meta-Data' in the context of a Sixth Framework call.

assistant: **Objectives**

We are witnessing a tremendous proliferation of database sources in many aspects of our lives. These sources contain large volumes of information, and are heterogeneous in their design and content. To make meaningful use of this information, modern information systems need to be able to understand, process, query, integrate and maintain it.In successfully performing these tasks, metadata plays an important role. Metadata examples include schema information, data constraints, user comments, ontologies, quality parameters, data annotations, provenance information, etc. Unfortunately, existing database systems do not provide true support for metadata. This forces data administrators to manually perform the metadata management task which is laborious, time consuming and error-prone. Although there are a few systems developed for that goal, they are usually ad hoc applications and are limited to certain kinds of metadata only.The objective of this initiative is to promote research in that area. The ultimate goal is to provide common techniques and tools for efficiently and effectively managing data and metadata. This direction is justified by two main observations. The first is the fact that the volume and the different kinds of metadata have grown extremely large, and manual techniques will soon become practically impossible to apply. The second is that the distinction between data and metadata has been blurred to the point where the same piece of information is seen as data by some people and as metadata by others.Our research will focus on two different approaches. One is the development of sophisticated techniques to support the metadata processing requirements, and enhance with them the existing database management systems. The second is the reduction of the different k
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'ACCESS to CEL-V LASER FACILITIES' (1994-1998).

assistant: **Concept**

The PHEBUS laser facility is located near Paris at the Centre d'Etudes de Limeil-Valenton (CEL- V) of the French Commissariat a l'Energie Atomique. This 2-beam Nd-glass laser, the most powerfull in Europe, the third in the world can deliver on target 9 kJ at 0,53 mu m and 7 kJ at 0,35 mu m for 1,4 ns pulse duration. A third beam is available with I kJ energy at 1,05 mu m tor the X-ray diagnostic of the plasma created by the main beams. The beams can be smoothed and/or have a width spectrum. The experimental area is fully equiped with all kinds of measuring instruments for plasma diagnostics IR to Xray calorimetry, spectroscopy, imaging and streak cameras with spatial, temporal, spectral resolutions; also available neutron diagnostics and imaging, radiochemistry. If necessary special diagnostics can be designed, existing diagnostics adapted. PHEBUS can be used for various kinds of experiments: energy absorption, X-ray conversion. X-ray laser, parametric and Raleigh-Taylor instabilities, atomic physic, plasma spectroscopy. implosion experiments... The guest physicists have the assistance of the whole physical and technical team of the CEL-V for laser, plasma diagnostic, target, data acquisition and processing. Offices are at their disposal and they can use the logistic facilities of the CEL-V restaurant, bus...
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Sound-Light Manipulation in the Terahertz' (SOULMAN).

assistant: **Concept**

The interaction of electromagnetic radiation with the mechanical vibrations of solids affects and determines many different physical phenomena. At the microscopic level, scattering of light with phonon excitations is a well known process exploited in semiconductor devices like Raman amplifiers and acousto-optic modulators. At the macroscopic scale, the interaction is mediated by the radiation pressure and is raising considerable interest as a way to excite and control mechanical oscillators, allowing, for instance, the refrigeration of a macroscopic object near the quantum limit.This rich physics has been mostly developed in the visible or near-infrared spectral ranges. The progress of quantum cascade technologies now offers a new device platform where to explore concepts for the reciprocal manipulation of light and vibrations with unprecedented possibilities. The accessible THz spectrum is in fact particularly intriguing. The wavevector of the electromagnetic field can be tuned to that of the vibration, be it a phonon or the oscillating mode of a macroscopic object, enhancing selectivity and strength of the interaction. The low radiation frequency then makes it technically feasible to optically couple mechanical elements at distances much smaller than the wavelength, allowing, for instance, to exploit optical forces between surface plasmon modes atop metallic membranes. Lastly, it is foreseeable  to include mechanical oscillators within the laser cavities, thereby creating new laser dynamics driven by the radiation pressure, and developing opto-mechanical effects in an active device where they can be studied, and eventually controlled, through the laser emission.SouL Man aims at establishing the field of THz opto-mechanics, relying on quantum cascade lasers for investi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'High Efficiency Real-Time Multithreading Engine for Space applications' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

TAITUS, a company with a 12+ years success track record providing services to the most relevant players in the space sector (e.g. ESA, THALES, AIRBUS) and big companies (e.g. PETROBRAS). Moreover, our talented professional team is composed by renown experts in the Space sector, as is the case of our CEO, Mr Felipe Martín-Crespo (15+ years’ experience as ESA’s Technical Officer of the Envisat Payload Data Segment development, in the Earth Observation Projects Division), or Mr Stephen Wu (25+ years’ experience in the field of Earth Observation, 15+ years’ experience in ESA’s establishment in Frascati, Italy).HERMES is a SW development ecosystem (HERMES SDK plus applications, plugins and services)that allows building quickly and efficiently SW systems for the space industry.1. Models successfully proven on-the-field on rigorous missions (e.g. Sentinel program)2. Our high quality SW Development Kit (SDK) let our clients save more than 65% of development cost, thanks to its high modularity and our SDK license cost is 50% cheaper than those from our competitors with equivalent features.3. Uncompromised embedded visualisations engine.More importantly, we offer a unique boost in execution performance.1. Our proprietary General Purpose Graphic Processing Unit (GPGPU) algorithmic (10x-100x boost in processing speed) let our clients obtain the results of the complex calculations involved in satellite-data acquisition missions in a few minutes instead of waiting several hours, which directly impacts their satellite-data consumption strategy (75% costs reduction).2. Moreover, this is a unique selling point that none of our competitors can offer and our main competitive advantage.3. Furthermore, timeliness is critical in applications such as disaster warning systems, where response
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'MARIE CURIE FRANCE REGIONS' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The MCFR proposal is coordinated by CPU (Rectors Conference, already NCP-Mobility and Bridgehead Organisation for Euraxess/Era-More). The proposal is to create a national programme, very open in terms of topics, with a large geographical span.  Though it would be a new programme (option B), it has not been established ex-nihilo. The proposal is based on 14 existing regional programmes of mobility. The MCFR would connect these programmes, which are currently completely independent. Yet they have one common feature: a strong and structural influence over university mobility policies in their respective territories.  However, in light of their relatively modest size and their position at the regional level, they cannot benefit from promotion, publicity and recognition outside of France/ abroad.   The principle behind this project is to combine the initiative efforts of these regions in favour of the mobility of researchers/fellows and to increase project size. The key points of our project are: - A progressive standardization of selection procedures and recruitment, region by region, inspired by the recruitment methods used for MCF - The standardization and improvement of promotion and communication efforts (see annex) - The significant increase in the number of fellowships, as well as their length, and the improvement of the conditions of mobility - Reaching out to a large  number of universities and of research laboratories all over France - No research topic is to be excluded a priori  The MCFR programme offers more than 300 fellowships-years for incoming and outgoing mobility.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Macroevolution of European Literature', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The MELT project will study the macroevolution of European literature: the overarching patterns of intertextual influences in literary fiction spanning the years 1800–2000 and including all major European languages. This project will rely on the full-text digital library of unprecedented size – HathiTrust, with over 10 million full-text books – as well as on advanced methods of computational text analysis and on novel mathematical models of cultural evolution. My interdisciplinary team, consisting of scholars of digital humanities, computational linguistics, and mathematics, will construct massive dynamic networks of book history, capturing the thematic influences between athors, the emergence of new literary communities (e.g., genres), and their decay. In this way, the MELT will essentially build a gigantic “map” of European literary history, having two dimensions: geographic and temporal. In parallel, we will simulate the evolution of books, creating artificial “authors” powered by large language models. Such simulations will allow testing the robustness of our network construction methods.The study of this massive size and scope, employing a powerful computer cluster, will allow answering many fundamental questions about literature – but also about society and politics, since literature often reflects moods and aspirations of the day. For example, what is the role of demographic turnover in the change of literary topics? How do disruptive events – wars, pandemics, and revolutions – influence the fabric of writing? What makes certain books bestselling and, as a consequence, hyper-influential? Do literary genres gradually loose their appeal due to repetetiveness? Literature occupies a central part of culture, shaping our identities and visions of the future, but our un
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'COMBUSTION OF INDUSTRIAL BIOMASS WASTE FOR PRODUCTION OF HEAT AND POWER TO COVER ENERGY NEEDS IN HORTICULTURAL INDUSTRY'.

assistant: **Innovation**

The demonstration of an energy efficient installation for energy recovery from industrial biomass waste (saw dust from fibre board): an advanced system for combustion (water cooled grate to avoid sintering), control (low emissions) and energy conversion (small scale steam turbine). Heat (3.0 MWth) and power (0.4 MWe) are used by horticultural industry for heating and illumination of greenhouses.The project aims to demonstrate the technical and financial feasibility of useful exploitation of industrial biomass waste streams (currently dumped) with strongly reduced emissions compared to existing technology.Main technical data are :- Capacity : 4.0 MWth- Electricity use : 0.43 MWe- Steam use : 2.93 MWth- Gross efficiency : 84%- Energy conservation : 94,890 GJ/a 2,260 toe/y 13,600 ton CO2/yThe heart of the installation is a biomass to energy furnace and a steam turbine. The combustion system is based on a water cooled grate for fines (sawdust). The superheated steam is fed to a condensing steam turbine.The capacity is 0.4 MWe and 3.0 MWth during 7150 operating hours per year based on 6450 tons of biomass waste a year (16 MJ/kg Calorific Lower Value). The emission control is by monitoring CxHy and O2 in the flue gas and subsequent control of primary/secondary air and fuel supply. CxHy and CO emissions compare favourably with conventional installations and NOx emissions are relatively low. Particulate emissions will be kept under 25 mg/nm3 (considerably lower than normal) through electrostatic filter. The electricity and heat is used for heating and illumination of greenhouses. Because there will be differences between the heat capacity needed and the capacity produced, heat storage tanks will be installed. In a recent study by TNO-MEP a life cycle analyses is performed for d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Spark Plasma Sintering Nanostructured Thermoelectric Sulphides' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Thermoelectric (TE) power generation, which offers potential for converting waste industrial heat into useful electricity, is foreseen to become increasingly important in the near future because of the need for alternative energy sources. How big this role is likely to be depends not only on the efficiency of TE materials but also on the crustal abundance and toxicity of their raw materials. BiSbTe intermetallic compounds, PbTe and SiGe alloys have served as the most widely used TE materials in the past half century. However, the key constituent elements, such as Te (0.001 ppm by weight), Sb (0.2 ppm), and Ge (1.4 ppm) are rare in the Earth’s crust, and Te and Pb are toxic. In this project, TE sulphides operating in the medium temperature ranges, instead of tellurides are chosen as the research starting point to explore TE materials with high figure of merit zT, which requires higher Seebeck coefficient, higher electrical conductivity, and lower thermal conductivity. A combination of band structure engineering and nanostructuring will be simultaneously investigated as an effective approach for improving TE performance. We will identify promising optimized compositions and sinter powders by Spark Plasma Sintering (SPS) to produce three kinds of TE metal (Cu, Bi, Ti) sulphides. Also, grain size and morphology controllable bulk nanomaterials will be fabricated by nonequilibrium routes, for example, melt spinning or mechanical alloying followed by SPS. The main objective of this work is to develop high performance nanostructured TE sulphides and modules to replace current commercial materials that use costly, scarce and toxic elements. Moreover, this project will help to clarify the physical mechanisms behinds the two strategies, band structure engineering and nanostructuri
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Amygdala Circuits for Appetitive Conditioning' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The project outlined here addresses the fundamental question how the brain encodes and controls behavior. While we have a reasonable understanding of the role of entire brain areas in such processes, and of mechanisms at the molecular and synaptic levels, there is a big gap in our knowledge of how behavior is controlled at the level of defined neuronal circuits.In natural environments, chances for survival depend on learning about possible aversive and appetitive outcomes and on the appropriate behavioral responses. Most studies addressing the underlying mechanisms at the level of neuronal circuits have focused on aversive learning, such as in Pavlovian fear conditioning. Understanding how activity in defined neuronal circuits mediates appetitive learning, as well as how these circuitries are shared and interact with aversive learning circuits, is a central question in the neuroscience of learning and memory and the focus of this grant application.Using a multidisciplinary approach in mice, combining behavioral, in vivo and in vitro electrophysiological, imaging, optogenetic and state-of-the-art viral circuit tracing techniques, we aim at dissecting the neuronal circuitry of appetitive Pavlovian conditioning with a focus on the amygdala, a key brain region important for both aversive and appetitive learning. Ultimately, elucidating these mechanisms at the level of defined neurons and circuits is fundamental not only for an understanding of memory processes in the brain in general, but also to inform a mechanistic approach to psychiatric conditions associated with amygdala dysfunction and dysregulated emotional responses including anxiety and mood disorders.