RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Morphological and molecular phylogeny of the Psylloidea (Insecta, Hemiptera): an integrative approach to resolve ancient relationships between insects and host-plants' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

Psylloidea is a basal group of Hemiptera whose internal affiliations are not well understood. This study will attempt to infer relationships between closely related groups of Psylloidea. The approach involves recognition and selection of relevant morphological and molecular characters for cladistic analysis.Homologous morphological characters will be particularly identified in the head of Psylloidea, and their phylogenetic information will be tested. Interspecific variations in structure and homology of these characters will be defined. A second set of molecular characters will be based on nucleotide sequences of 18S rRNAs, as well as on coding gene sequences.Character homology will be established through an alignment based on secondary structure, site by site. Phylogenetic analyses using the morphological and molecular data sets will give for the first time a framework phylogenetic estimate for Psylloidea.This broader phylogenetic context is needed to test hypotheses about plant-insect relationships: evolution of gall production, synchronization of life cycles between host-plants and insects, or role of the host specialization in the evolution of the group. This description of biodiversity for a group of insects of economic importance will require a multi-disciplinary competence in systematics.The project will be firstly conducted at the Museum of Natural History in Basel (Switzerland), where the only active specialist of the group (D. Burckhardt) is in charge of the second most important collection of psyllids in the world. The return phase will take advantage of the theoretical and practical expertise of the return research team in testing evolutionary models of evolution.The mutual benefits of such a promising cooperation between a EU Member State and a Third Countr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Set theory, topology and Banach spaces' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Our research plan has two main strategical lines. One is to apply the advanced methods in set theory that we have learn along our stay in Paris as IEF fellow into Banach space theory, through collaboration and discussion with the Functional Analysis group in Murcia and other places in Spain. The other line is to continue our research in the border line of set theory, topology and Banach spaces in such topics as infinite-dimensional topology or spaces of continuous functions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'At first INsight: how our memories shape empathy for others’ physical pain' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Empathy is a multifaceted concept. It mostly relies on the ability to mirror and to explicitly infer others’ inner states. The simulation-theory (ST) account of Theory of Mind (ToM) suggests that people build an accurate representation of others’ inner states by using one’s own mind as a model, i.e. internally simulating others’ mind; for Theory-Theory (TT) such a representation is formed on the basis of common knowledge. Accumulating evidence supported the idea that our memories interact with empathy in building a representation of others’ inner states. In a series of two experiments, the current proposal is aimed at determining how, if any, the recruitment of autobiographical memory occurs when we empathize with others’ emotional experience, such as physical pain. Connectivity analysis applied to oscillatory activity, such as pattern similarity analysis, revealed that neural patterns present during memory formation are reactivated during memory retrieval, thus being a powerful tool to monitor a memory trace. By further combining excellent temporal resolution of electrophysiological measures and the excellent spatial resolution of functional imaging data in a multimodal EEG-fMRI recording, MEMPATHY aimed at establishing whether our memories are reactivated when we empathize with others' pain even when reactivation of our memories is detrimental to build an accurate representation of others’ pain. Importantly, by means of multi-modal neuroimaging measures and connectivity analysis, the proposal will allow to individuate the pathway and the direction of the dynamic communication within the brain network underlying memory and empathic processes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Integrated, Fail-Operational, Cognitive Perception, Planning and Control Systems for Highly Automated Vehicles'.

assistant: **Innovation**

NewControl will develop virtualized platforms for vehicular subsystems that are essential to highly automated driving (realizing functions such as perception, cognition and control), so as to enable mobility-as-a-service for next generation highly automated vehicles. Its overarching goal is to provide an industrially calibrated trajectory towards increased user-acceptance of automated control functions, through an approach that is centered on the premise of safety by design. Newcontrol will deliver:1.             Fail-operational platform for robust holistic perception through a combination of Lidar, Radar, and sensor fusion2.             Generalized virtual platform for stable and efficient control of propulsion systems3.             Cost- and power-efficient, high-performance embedded compute-platforms for in-vehicle perception, cognition, and control4.             Robust approaches for implementing, verifying, and certifying automated control for safety-critical applicationsSeveral (12) demonstrators will be built to showcase the project’s findings and their capability to facilitate perception, cognition and control of next generation highly automated vehicles.The developments in NewControl will facilitate significant cost reductions for essential modules necessary for future automated vehicles. Concomitantly, these developments will improve the safety and reliability of automated systems to levels necessary for mass-market deployment. These innovations will leverage the expertise of industrial (OEMs, Tier-1, Tier-2 and technology providers) and research partners along the complete semiconductor, automotive, and aviation value chains, providing Europe with a competitive edge in a growing market. Importantly, NewControl's innovations will improve the market penetratio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Transceivers for Analog Photonic Computation' under Horizon Europe.

assistant: **Concept**

Analog Programmable-Photonic Computation (APC) is a novel paradigm that exploits programmable integrated photonics (PIP) for high-performance optical computing and signal processing. The ERC-funded ANBIT project established APC’s foundation by defining the analog bit (anbit), introducing computational operations, and designing circuit implementations. However, a major challenge remains: the efficient generation and detection of anbits. Existing solutions rely on fixed optical components, making them susceptible to fabrication errors and operational drifts, limiting scalability and precision.TRANSBIT addresses this challenge by introducing reconfigurable photonic transceivers for anbit encoding and detection. By replacing static beam combiners with tuneable basic units of PIP, TRANSBIT enables real-time adaptive error correction, ensuring stable and high-fidelity operation. This approach not only enhances APC’s computational capabilities, but also facilitates its scalability and practical deployment.By overcoming a fundamental bottleneck, TRANSBIT paves the way for the transfer of APC technology to real-world applications. Its impact extends beyond computing, offering new opportunities in optical communications and neuromorphic photonic networks. This project marks a key step toward the integration of APC into next-generation photonic systems, unlocking its full potential for future technological advancements.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Mass spectrometric technology for next generation proteomics in systems medicine'.

assistant: **Concept**

Systems medicine designates the application of global approaches to human health and disease. Genomic technologies, especially next-generation sequencing, are already pioneering this new area. There is an urgent need to advance proteomics technologies to a similar level. This will help revolu¬tionize diagnosis and prognosis based on the expression levels and modifications of proteins in cells, tissues, organoids or body fluids. Our vision is to make mass spectrometry so robust and powerful that it will be present in every biological laboratory and in every clinic. The applicants are leaders in proteomics technologies from academia and industry and have an out-standing track-record in advancing both instrumentation as well as its application in biological and disease contexts. Here we come together to develop breakthrough technology capable of more than a factor ten improvement in parameters of performance of the mass spectrometric workflow, ena¬bling patient-oriented proteome profiling. The proteomics workflow will be automated, multiplexed and made ‘industrial strength’ - ready for high-throughput and in-depth clinical applications. Importantly, in addition to the identification of the main protein representative of a gene, we aim to routinely identify and quantify protein modifications and isoforms by using multidimensional approaches, including new separation, enrichment and frag¬mentation technologies. The breakthroughs aimed for will generate larger more biologically relevant data. This data will be merged with other ‘omic’ data and mined using machine learning technologies. Our results will establish the role mass spectrometry in systems medicine, making all workflows and mass spectrometry platforms available to the community. They will be used as the basis of myr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Wine Industry Accompanying Measure' in the context of a Fifth Framework call.

assistant: **Objectives**

This project will be carried out during 2 years and will include 5 participating countries: France, Italy, Portugal, Hungary and Israel. The final aim of this action is to improve the environmental conditions related to the wine industry, to increase the quality and healthiness of the product and to strengthen the social and economic cohesion in certain rural areas of the European Union. This should be obtained by solving three categories of problems encountered by SMEs from this sector: -safeguarding the environment related to the wine production, -increasing the quality of wine from the production to the distribution, -increase the competitiveness and innovation in the wine sector.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Unraveling redox regulation in cancer stem cells as a potential therapeutic target for breast cancer'.

assistant: **Objectives**

ABSTRACT Breast cancer (BC) is the most frequently diagnosed cancer and the first cause of cancer death in women worldwide. In many tumors, including BC, there is a population of cancer stem cells (CSCs) characterized for unlimited self-renewal and being resistant to conventional cancer therapies eventually leading to tumor relapses and metastases. Breast CSCs (BCSCs) show high cellular plasticity and are capable of shifting between a proliferative epithelial-like (E) state and a quiescent mesenchymal-like (M) state. This plasticity of BCSCs facilitates their ability to initiate and grow primary tumors, invade the basement membrane, traverse tissue vasculature, and ultimately colonize distant organs to form clinically significant metastases. It has been recently proposed that redox regulation might play a significant role in BCSCs plasticity and aggressiveness.  We hypothesize that the redox-regulated BCSC plasticity and the highly oxidative metabolism of E-BCSCs might be a vulnerability that could be exploited as a novel BC therapy. We aim to characterize BCSCs in terms of individual ROS production, transducing our breast cancer patient-derived organoids (PDOs) collection with genetically-encoded redox sensors. We will treat breast cancer PDOs with conventional chemotherapy and inhibitors of PI3K to study changes in redox signaling occurring in the tumor. Finally, we will attempt to target these cells and modulate their redox regulation in order to differentiate and eliminate them. We expect to better understand the redox-regulation of BCSCs, to subsequently modulate BCSC redox state to target and eliminate these cells, increasing conventional therapy effectiveness and decreasing the minimal residual disease and cancer spread in BC patients, contributing to overall sur
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Infinitary Rewriting for Type Systems' (InfTy) targeting Horizon 2020.

assistant: **Abstract**

Infinite objects are ubiquitous in computer science, e.g., an interactive program may be modelled as taking for input a stream (an infinite list) of requests and producing a stream of responses. In theoretical computer science infinite objects play an important role e.g. in automata theory and exact real number arithmetic. Representing and reasoning about infinite computations is crucial in designing safe software systems.The objective of InfTy is to devise mathematical methods for reasoning about programs manipulating infinite objects, developing compositional typed formalisms and integrating them with infinitary rewriting techniques. Our methods will be compositional and applicable to higher-order programs, while still adopting the operational perspective of rewriting, thus opening up a new viewpoint on higher-order typed formalisms for corecursion. We will extend Pure Type Systems with coinductive types, providing a general yet simple theory for type systems with infinite objects and unifying previous type-based and rewriting-based work on productivity. By establishing infinitary normalisation and infinitary confluence for typable terms, we will construct Böhm models for type systems with corecursion.Recently, a coinductive approach to infinitary rewriting has been proposed by Endrullis et al., and coinductive proofs for some results in infinitary rewriting have been developed by the fellow. The coinductive approach simplifies investigations in infinitary rewriting and thus it is our chosen methodology. This approach, which we will further develop, is by itself of high interest to the rewriting community, but our work will also be relevant to the typed lambda calculus and programming languages communities. The supervisor has strong expertise in rewriting, particularl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Decisions and Behaviors for Cognitive Automobiles Research' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The research presented herein belongs to the Intelligent Transport Systems and Services (ITS) field. ITS are application of information and communication technologies to the transportation system. The purposed work is to design behaviors and decisions for Autonomous Vehicles (vehicles that drive by itself, also known as the ""driverless cars""). After a correct interpretation of a traffic situation, the most appropriate behavior will be triggered, a path to follow will be designed, and the proper orders will be sent to the car actuators (steering wheel, throttle and brake).The host center, “Institut für Mess- und Regelungstechnik” of the Karlsruher Institute of Technologie (KIT) conducts research on Cognitive Automobiles. Specifically it operates 2 experimental vehicles. One of them participated in the Darpa Urban Challenge competition of autonomous vehicles and successfully reached its finals. And the team at KIT has won the 2011 Grand Cooperative Driving Challenge, an international competition of cooperative vehicles which took place in the Netherlands.Cognitive Automobiles research project is divided in three sub-projects: sub-project A: “Distributed Sensorial Perception”, sub-project B: “Behavior Decision, Generation, and Conduction”, and sub-project C: “Automobiles and IT Basis System”. This proposal will collaborate in sub-project B area. It will focus in two main tasks: First, the trajectories of cooperative vehicles at intersections are preplanned to optimize the expected flow of vehicles at a high safety level. Second, trajectories and maneuvers of cooperative vehicles are continuously monitored with respect to safety and are dynamically adjusted with respect to the actual safety level. To perform these cooperative maneuvers several vehicles will have to plan a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'World’s first absorbable percutaneous closure device for large venotomies'.

assistant: **Objectives**

Small venotomies (a hole in the vein to provide access for surgical procedures) are routinely made and closed using manual compression. As venotomies get bigger it becomes more difficult to close them, leading to complications (blood loss, haematoma, infection and thrombosis). Developments in transcatheter heart valve procedures and left atrial appendage occlusion requires large venotomies in the femoral vein to gain access to the heart. These large venotomies are difficult to close, leaving patients exposed to additional complications, pain and discomfort. Hence, there is a strong unmet medical need for effective methods to close venotomies.Vivasure Medical Limited is a Irish R&D performing medical device company, established in 2008 and secured a total of €45M funds. Vivasure developed the patented PerQseal platform technology as effective method for large arterial and venous closures. PerQseal Venous is the world’s first absorbable patch-based closure product for large venotomy closure (over 8 mm). By delivering an intra-venous patch without surgery, a surgeon can seal vessels from inside while providing a matrix to support wound healing. PerQseal Venous is largely based on Vivasure’s already existing and well-validated PerQseal®Arterial product, used to close arterial vessels and already in clinical use.Following clinical validation and preparation for EU and US wide commercialisation in the VENOCLOSE project, Vivasure will target the large and ever-growing venous closure market. Vivasure has successfully obtained ISO13485 Certification and CE certification for its arterial closure device, which will pave the way for PerQseal Venous. The company will leverage existing customer-base among cardiologists and distribution partner, contributing to a further de-risking of