RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Application of Mechanical Forces on Axon Growth Cones via Magnetic Nanoparticles to Enhance Axon Regeneration in Central Nervous System' (MagForce4AxonGrowth), addressing dissemination and exploitation.

assistant: **Impact**

The lack of axon regeneration following spinal cord injury (SCI) diminishes patients’ quality of life and poses a significant economic burden on the society. This project aims to investigate the complex axon guidance mechanism following a SCI scenario by applying mechanical tension on the growth cones (GCs) of central nervous system (CNS) axons via novel magnetic nanoparticles that are functionalized with neuronal cell adhesion molecule. It is hypothesized that the complex interaction of chemical and physical guidance cues at the cytoskeletal (CSK) level can be modulated by mechanically activating specific signalling pathways, e.g., RhoGTPases. To test this hypothesis, mechanical tension will be applied to multiple GCs simultaneously, using a magnetic tweezers system integrated with a microfluidic culture device, which grants exclusive access to axonal areas. The effect of tension on axon outgrowth will be characterized as a function of chemical and mechanical environment, while examining the roles of Rho GTPase signalling and CSK structure in this mechanotransduction process. In essence, this project poses a biological hypothesis that can only be tested using a combination of sophisticated engineering methods. The results of this multidisciplinary project will provide a better understanding of axon elongation mechanisms and potentially become a promising therapeutic approach for SCI. The fellow is a mechanical / biomedical engineer with experience in microfluidic neuron culture and live cell microscopy; whereas the host is a world leader in single molecule biophysics. This project will not only contribute to the scientific competency of Europe by tackling a very relevant medical problem, but also provide the fellow an excellent opportunity to gain high quality scientif
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Stellar HYdrodynamics Nucleosynthesis and Evolution' (SHYNE) targeting Seventh Framework.

assistant: **Abstract**

Stars, massive stars in particular, play a key role through the light they shine, all the chemical elements they produce and the supernova explosions that mark their death. Stars are complex 3D laboratories that relate to many scientific disciplines: nuclear & astro-physics, applied mathematics and computer science. Unfortunately stars cannot be modelled fully in 3D. The best way to model them is to develop synergy between 3D and 1D models to improve 1D stellar evolution models.This programme will tackle this multi-disciplinary challenge, which is out of reach of individual research groups. For this purpose, my team, with the help of a network of world leading experts in their respective disciplines, will use an innovating approach using and extending techniques from other disciplines such as Monte Carlo simulations (regularly used in other disciplines of physics) to develop a unique suite of software tools able to: (1) simulate the most complex processes in stars,(2) apply these models to stars of all masses and (3) use stars as virtual nuclear physics laboratories.This unique software suite will provide a pipeline for the fast production of comprehensive datasets (superseding currently limited ones) that will guide and provide a framework of analysis for large European nuclear physics experiments (FAIR at GSI, D) and astronomical observing facilities (ESO VLT, E-ELT & ESA GAIA) thus enhancing the return on these huge investments. The SHYNE software suite will also boost the innovation cycle of future developments in stellar modelling far beyond the term of this grant and will enable the resolution of many challenging questions and unsolved problems such as: What is the fate of the most massive stars known to date? How frequent are pair-creation and electron-capture su
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'iPerm: Guided wave monitoring tool'.

assistant: **Concept**

Today, there are more than 40 major transnational oil and gas pipelines traversing Europe, accounting for over 34,565 km of strategically critical pipeline infrastructure, 40% of which are over 40 years old and subject to corrosion induced catastrophic failures impacting negatively upon European society and its economy. With such an extensive and growing network of pipelines, and a corollary increasing incidence of failures, it is no longer feasible to rely upon current intermittent manual inspection techniques to maintain safe operation, from the twin perspectives of probability of detection over such large network, and consequence of failure given the hazardous materials being distributed. Clearly, a wide-area coverage Structural Health Monitoring solution is overdue. The iPerm project seeks to address this challenge by developing a permanent, intelligent and energy-efficient wireless monitoring network which will deliver a step-change improvement over existing inspection systems, and thus a step change in the safety and reliability of Europe’s pipeline network.The FTI Pilot is the ideal instrument us, a trans-disciplinary and cross-sectoral consortium, to utilize in order to commercialize a technological solution that has already gained traction in the market. It will enable us leverage our own investment and reduce the time required to refine and scale up our concept in order to deliver it to international markets. Our vision is to capture 3,3% of the Oil & Gas segment, the fastest growing segment of the global NDT market, within 5 years following product launch aiming to add (cumulatively) €26.79 million to our top-line and generate more than €6.93 million in operating profit resulting to an investment multiple of 2 times the European funding. In addition, we will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Complex dynamics in higher dimensions: Fatou Theory' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

Dynamical systems occur as models in all the physical sciences. One dimensional dynamical systems have been studied to great depth but their use as models is limited. Higher dimensional systems have recently received great attention but they tend to be much more complicated. We propose to study complex dynamical systems in dimensions two and higher. The main emphasis is on the set where the dynamical behavior is orderly, called the Fatou set. In one complex dimension the Fatou set is completely understood but in higher dimensions many important problems are completely open. The reintegration grant will enable us to create an excellent research environment for complex dynamical systems in Amsterdam. Funds from the grant will be used to support the research of the applicant, set up a complex dynamics seminar at the University of Amsterdam, invite guests to Amsterdam and organise a workshop in several complex variables. The grant will also allow the applicant to spend one semester in the United States where he will solidify his connections with strong complex dynamics groups at SUNY Stony Brook and the University of Michigan.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for '3D Printing of Novel 2D Nanomaterials: Adding Advanced 2D Functionalities to Revolutionary Tailored 3D Manufacturing' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

My vision is to establish, within the framework of an ERC CoG, a multidisciplinary group which will work in concert towards pioneering the integration of novel 2-Dimensional nanomaterials with novel additive fabrication techniques to develop a unique class of energy storage devices.Batteries and supercapacitors are two very complementary types of energy storage devices. Batteries store much higher energy densities; supercapacitors, on the other hand, hold one tenth of the electricity per unit of volume or weight as compared to batteries but can achieve much higher power densities. Technology is currently striving to improve the power density of batteries and the energy density of supercapacitors. To do so it is imperative to develop new materials, chemistries and manufacturing strategies.3D2DPrint aims to develop micro-energy devices (both supercapacitors and batteries), technologies particularly relevant in the context of the emergent industry of micro-electro-mechanical systems and constantly downsized electronics. We plan to use novel two-dimensional (2D) nanomaterials obtained by liquid-phase exfoliation. This method offers a new, economic and easy way to prepare ink of a variety of 2D systems, allowing to produce wide device performance window through elegant and simple constituent control at the point of fabrication. 3D2DPrint will use our expertise and know-how to allow development of advanced AM methods to integrate dissimilar nanomaterial blends and/or “hybrids” into fully embedded 3D printed energy storage devices, with the ultimate objective to realise a range of products that contain the above described nanomaterials subcomponent devices, electrical connections and traditional micro-fabricated subcomponents (if needed) ideally using a single tool.


**Keywor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Aerogel-Based Composite/Hybrid Nanomaterials for Cost-Effective Building Super-Insulation Systems' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

In the context of global climate control policies, improving the energy efficiency of existing buildings represents a great challenge, worldwide as well as at the European level. Reducing the energy consumption of buildings is nowadays preferably achieved by increasing the thermal resistance of the insulation layer in the building envelope. The AEROCOINs project will make a significant contribution to the future reduction of energy consumption by decreasing heating and cooling demands of existing-buildings. A clever combination of sol-gel science and nanotechnology can greatly advance design and development of novel superinsulating aerogels. The AEROCOINs project proposes to create a new class of mechanically strong superinsulating aerogel composite/hybrid materials by overcoming the two major obstacles which have endured for so long and have prevented a more wide-spread use of silica-based aerogel insulation components in the building industry: i) strengthening of silica aerogels by cross-linking with cellulosic polymers or the incorporation of cellulose-based nanofibres and ii) lowering the production cost of monolithic plates or boards of composite/hybrid aerogel materials via ambient drying and continuous production technology. Acting on these two incentives, new superinsulating aerogel-based monolithic materials with improved thermo-mechanical properties will be synthesized at the laboratory scale, developed further to the pilot scale under the shape of superinsulating panels, integrated in well-suited envelope components which will then be used for energy and ageing evaluation purposes via the integration of the aerogel-based components in a demonstration wall. In addition, a complete LCA study of the component will be realized and a fabrication concept for cost e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Design and Manufacture of Scaled up 50 kg capacity Plasma Melt Overflow (PMO) system for the commercial production of titanium and iron-chrome-aluminium alloy fibres.' to be submitted under Horizon 2020.

assistant: **Abstract**

A previously funded FP7 project MEMLAB has opened new business opportunity for the mass scale titanium fibre application to a novel lead acid battery market. 75.2 million lead acid batteries are used in Europe. Capturing 4% of this market by titanium fibre substrate technology will require 3 million of these batteries and 301 tonnes of titanium fibre production yearly. Currently titanium fibre is used only for very specific applications  due to the complexity of the production process and high price. In order to satisfy the new market opportunity, a melting and casting process capable of producing fibres directly from a melt using scrap as a source is required to reduce costs of the fibres. We have developed a 200g prototype PMO system through a new process by integrating plasma arc melting to our unique melt over flow process. This is capable to produce titanium fibre from titanium scrap with specific shape required for the battery. Our system is 41 times cheaper and will create several new titanium fibre market applications. In order to be commercially viable, we would need to upgrade our PMO system from 200g to 50kg capacity, which would be able to produce 550 tonnes of titanium fibres per year. The PMO process can be applied to produce other metallic fibres e.g. FeCrAl alloy fibres to be used as the advanced catalyst coating substrate material for self-regenerative Diesel Particulate Filters (DPFs). FeCrAl alloy substrate is a good candidate for the next generation of DPFs due to its advantages of reduced cost and superior performance in filtration efficiency (more than 90%) and passive regeneration through soot burn-off. This has a huge business potential and is timely, especially as Euro VII legislation will require zero particulate emissions from diesel vehicles
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Bgv-banc de couchage à grande vitesse' (BGV).

assistant: **Concept**

Description:The BGV equipment of CTP is a high speed coater(2000m/min) with on line soft calender and super calander off line. It is specifically designed to perform R&D studies related to surface treatment of coated paper and board. -All the newly developed coating techniques are available on the coater, on 2 stations: unit 1: for coating of 1 paper side at a time; unit 2: for coating of 2 paper sides at a time -The main drying techniques are available: electrical and gas infrared, air flow -Paper and coating colour can be heated to industrial temperatures. The following topics can be studied: -flow behaviour of coating colour as a function of coating parameters in the different coating heads, -base paper behaviour along the coater, soft calender and supercalender:- drying of coat along the machine;- calendering as a function of the pressure, temperature and kind of elastic presses.Main results: activities supported by the contract:50 experimental days offered to researchers during contractual period16 proposals have been accepted for 26 proposals submitted14 users groups have been involved in the different projects28 individual Users validated their work under industrial conditions7 different countries had a share in the contract 11 meetings took place.Application:Please contact Project Manager directly. Publication of the opportunities for access: - An advertisement published in: PULP AND PAPER EUROPE, April 2000, PPI Head Quarters, Chaussee de Charleroi 123a, Box 5, B - 1060 BRUSSELS (Belgium) - A mailing has been addresses to the European research laboratories, institutes, universities that work in the field of coating and calendering.Project Manager:Véronique Morin, Product Quality Division, Domaine Universitaire, Grenoble 38044, B.P. 251, FranceTel: +33-4-7615403
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Artificial Translation with Dynamic Foldamers: Relaying Encoded Messages into Chemical Function'.

assistant: **Concept**

We propose to apply the power of synthetic chemistry to a new challenge in synthetic biomimicry: the translation of encoded information into molecular function. We propose to design and build switchable synthetic molecules that are capable of communicating and processing information. This ambitious aim will be achieved through new classes of extended dynamic molecules that respond to their environment by changing shape, principally by invertase polarity/directionality. They will receive, communicate, amplify, transmit, and process information encoded in their molecular conformation and orientation. New analystic methods will be developed to explore their kinetics and thermodynamics. Characterized by a high level of intramolecular structural organization, they will participate in strong, selective mutual interactions, allowing them to process information through intramolecular and intermolecular interactions in simple and complex mixtures, both solution and in the membrane phase. These chemical systems will be able to extract information from their environment (the presence of a specific metal or organic molecule, a genetically encoded message, pH, or irradiation at a specific wavelength) and process it into chemical function. Life takes information in the form of bond polarity encoded in base pairs and translates it into biochemical function in the form of protein structure, and our synthetic structures will likewise translate molecular polarity into function by using new classes of promiscuous Watson-Crick-like base-pairs, able to switch between alternative hydrogen-bond polarities. Applications for these synthetic communication systems will ultimately see them embedded into cell membranes, allowing the selective control of function by communicating into the interior o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'FUNCTIONAL CONNECTIVITY IN CORTICAL MICROCIRCUITS' (FUNCCOMI).

assistant: **Concept**

The aim of this project is to understand the fundamental computation that underlies normalization in cortical sensory circuits. Neuronal responses during sensory processing depend on the statistical properties of the sensory stimuli as well as on the macroscopic organization of the cortical network that together facilitate the functional interplay between neurons within the network in order to perform complex computations. One such important computation that has been shown to operate in various neural systems is normalization. Normalization is the process in which the response of a neuron is modulated by the activity of a pool of neurons. A key question concerns the mechanism that results in normalization. Specifically, how the functional connectivity and interplay between excitatory and inhibitory neurons within a network facilitates this complex computation.Using two-photon microscopy, I will image calcium or voltage responses from a large population of neurons in the visual cortex of mice, and quantitatively characterize the evoked response of every neuron (excitatory vs. inhibitory, simple vs. complex, etc.). Then, I will make slices of the imaged areas and identify the active neurons in the slices by registering images obtained in vivo and in vitro. Finally, I will map the connectivity between the neurons using photo-stimulation, by sequentially evoking action potentials in every neuron while simultaneously measuring the postsynaptic activity of the rest of the neurons in the slice.This study will reveal the design principles of the functional connectivity of a sensory cortex and provide new insights into the relation between the connectivity and the functionality involved in processing sensory information in the cortex.