RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Understanding the chronic neurological alterations of down syndrome and their associated phenotypes and development of molecular targets for their correction (T21 TARGETS)' under Fifth Framework.

assistant: **Concept**

Despite a vast amount of investigation on the pathophysiology of Down syndrome (DS) (T21), the molecular, biochemical and cellular bases of this common cause of mental retardation (over 500.000 cases in Europe) are still unknown. The sequence of human chromosome 21, cells and tissues from individuals with partial or regular T21 (molecularly and phenotypically described) and functional approaches (expression profiling, yeast double hybrid, transcriptome and proteome) should permit: a/to identify the molecules that are involved in DS brain alterations and the modifier factors responsible of the phenotypic variability; b/to modelize the dosage effects of the DS transcriptome in mouse; and c/ to develop protective and therapeutic strategies for the treatment of the chronic neurological alterations of DS patients. This understanding of DS should also provide basic knowledge about the causes of common clinical neurological alterations in humans.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Genomics and the Analysis of Complex Traits'.

assistant: **Concept**

Complex traits are determined by the combined action of several genes and the environment. They are characterised in quantitative terms using statistical methods and it is increasingly recognised that many common human diseases such as cardiovascular disea se, cancer, psychiatric illness, autoimmune and inflammatory disease fall into this category. Susceptibility to prevalent infections, or to disease following infection (in humans, domesticated and wild animals) can be so described as can most of the traits of greatest interest in evolutionary biology such as fitness, viability, and reproductive success. The development of genomic technology in recent years has had an immense impact on all areas of genetics and evolutionary biology. The theory describing t he fate of genes in populations was reformulated; there is increasing recognition that linkage between genes, and disequilibrium which arises in populations between linked genes is important. Genetic mapping and genome sequencing programmes of human, mouse and other organisms have generated many markers for mapping genes influencing complex traits in human populations as well as those of wild animals and model organisms. All these areas under active research in this department. These developments have le d to a requirement for training young researchers working in the area of genome studies in population and statistical genetics, quantitative genetics and bioinformatics in an environment which exposes them to state-of-the-art science. This proposal will br ing such trainees to a department world-ranked in evolutionary and quantitative genetics with large concentration of internationally recognised scientists working in diverse areas. This department held a Marie Curie award under the FP5 scheme for short-ter m visits
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Scenarios for a sustainable society: Car transport systems and the sociology of embedded technologies'.

assistant: **Objectives**

Project summary The project has four main objectives: - To contribute to an understanding of what is involved in creating a 'sustainable society', through a focus on how moves towards social sustainability impact on social structure. The particular focus of this project is transport and the issue of sustainable mobility. - With respect to transport systems, to understand how specific transport technologies, those associated with the private car, become deeply embedded or 'buried' in the social structure of given societies. - To ascertain how such buried technologies distribute environmental risks, consumption costs, and mobility and employment benefits unequally across different social groups. - To construct a number of scenarios for changing the technology and establish the implications of each for the social redistribution of risks, costs and benefits. The project is designed as a series of parallel case studies of five medium sized European cities. These cities are chosen to represent both different national contexts and different forms of public transport policy. In each city the national research team will collect data on the politics of car transport, the differential environmental risks and pollution associated with car transport, the number and type of jobs generated by the car system, the understandings of car transport held by particular social groups, and the possibilities of reducing car transport through the use of information technology. With this empirical information each team will develop scenarios showing the social consequences of alternative forms of transport in its city. These scenarios are designed to stimulate informed public debate and to open policy options towards forms of sustainable mobility.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Integrated, Modular, Multisensing, Mid- and Near- IR sensing platform' (M3NIR).

assistant: **Concept**

Photonics-based sensing in the mid-IR been proven to be the key technology for highly efficient sensing in a plethora of applications ranging from environmental monitoring  to industrial process control, medical diagnostics, water quality, safety applications, medical and more. Related to other sensing approaches, mid-IR spectroscopy-based sensing enables the fast, reliable, and consumables/maintenance-free operation for the detection of trace amounts (even in the sub-ppb range) to high concentration of the targeted analytes. The interest in the technology has been significantly increased due to the maturing of the Quantum Cascade Lasers (QCLs). QCLs offer an up to 2-orders of magnitude enhancement in the signal-to-noise ratio while enabling the direct access to the characteristic molecular fingerprint region of the targeted analytes. M3NIR develops very innovative (currently at TRL2) mid-IR sensing approaches to significantly boost the technology in terms of performance (low limit of detection, multiple-species detection), footprint (co-integrating of lasers and components) reduction of energy consumption and cost. For the latest two, M3NIR implements detector-free sensing by means of the self-mixing detection scheme. Moreover, the combination of mid-IR and near-IR components in photothermal sensing is yet another approach for the implementation of miniaturised, energy efficient and low-cost advanced sensory system. To accomplish its goals, M3NIR co-integrates advanced electronics and data processing units in the systems as well. M3NIR demonstrates its novel approaches at TRL5 for the monitoring of GHG and ships emission (a drone-mounted sensor to be demonstrated), detection of phosphates and nitrates in water and the breath analysis for health and well-being related a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Development of Identity and Relationships during Transitions in Adolescence' under Horizon 2020.

assistant: **Concept**

A key developmental task in adolescence is the development of identity, which coincides with development of autonomy in close relationships. The INTRANSITION project aims to examine how development of identity and autonomy affect each other during adolescence. The project will advance the field by examining intra-individual (or within-person, as opposed to inter-individual or between-person) processes of change in identity and autonomy. This is crucial as inter-individual processes are not related or translatable to intra-individual processes. Often theories are examined by comparing adolescents to other adolescents, whereas the theoretical question focuses on understanding developmental changes within adolescents. To this end I will apply innovative intra-individual techniques to analyze development of identity and autonomy at different time scales: real-time moment-to-moment behavior, interactions across hours and days, and long-term development. In five interrelated work packages, I will examine development of adolescent identity and autonomy by putting the individual back in development. Work package 1 focuses on short-term intra-individual developmental processes of identity and autonomy. Work package 2 examines how developmental transitions affect intra-individual development of identity and autonomy. Work package 3 will focus on how person-environment interactions moderate intra-individual development of identity and autonomy. Work package 4 will examine emotional and behavioral variability in intra-individual development of identity and autonomy. Work package 5 addresses gene-environment interactions and epigenetic processes in intra-individual development of identity and autonomy. Together, these work packages will offer a better understanding of the short-term
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Paradoxical social representations and multimedial communications images and words as source and vehicle of potentially diversified dimensions of social representations' to be submitted under Fourth Framework.

assistant: **Abstract**

Research objectives and content Over recent years, growing - even if still relatively limited - attention has been focused on the paradoxical and contradictory nature of Social Representations expressed and generated through mass communication (for a review, see Moscovici 1996). On the basis of several researches that show that the image can constitute an independent communication system with regard to the verbal system, and one capable of carrying with greater facility stereotypic and stigmatising dimensions of Social Representations (de Rosa, 1987,1990; Gilman, 1988; de Rosa & Schurmans, 1994; Shoeneman et al. 1994), the objective of this research is to verify two hypotheses. The first hypothesis is that the verbal and iconic parts of the messages transmitted through the press frequently express diversified and contradictory dimension of Social Representation of the AIDS victim and of the mentally ill. The second hypothesis is that, through the visual communication employed by the press, stereotypic and stigmatising dimensions of Social Representation towards the AIDS victim and the mentally ill are expressed, which, on the contrary, when the rationalising filter of verbal language intervenes. are not expressed with the same probability. The verification of these hypotheses will be based on the content analysis of the visual-verbal texts found in daily newspapers and magazines and having as their object the AIDS victim and the mentally ill. To verify these hypotheses, a reasoned selection of textual and iconographic materials will be analysed, including not only Italian newspapers and magazines, but also, in keeping with the cross-national nature of this research, English and French ones. Training content (objective, benefit and expected impact) The chose of the two h
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Wind generator system with significant technical advantages over existing technology and particulary suited for integration into the built environment .'.

assistant: **Objectives**

The proposed project relates to the design, development and prototype building of an innovative wind generator system which has been invented by Count Alain de Briey. The system is thought to have competitive advantages over existing wind energy systems, for both technical and economic reasons. Technically it combines the advantages of both horizontal and vertical axis type wind generators , without the disadvantages . Additionally , the system is conceived in such a way that it can be integrated into the built environment , i.e. close to the consumption of electrical energy, thereby reducing transmission losses . The possibility to integrate the system into the built environment is an important economic issue , as this ability allows with energy systems to compete with other renewable energy technologies, in particular solar photovoltaic technologies, for which an enormous future market for building integration is expected.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Ecosystem for rapid adoption of modelling and simulation METhods to address regulatory needs in the development of orphan and paediatric medicines'.

assistant: **Innovation**

ERAMET will provide an integrated approach for developers and regulators’ decision-making for paediatric and orphan drugs, centred on the drug development questions. This will constitute a transparent ecosystem for drug development and assessment, that will facilitate the adoption of modelling and simulation (M&S) methods and related data types (including real word data such as registries and electronic healthcare data).The overall objective of ERAMET is to provide and implement a framework for establishing the credibility of M&S methods and related results as sources of evidence within regulatory procedures.The ecosystem proposed by ERAMET will be based on three pillars: (1) A repository connecting questions, data and methods.(2) The development and validation of high-quality standards for data and analytical methods (including M&S and hybrid approaches). These will cover computational M&S, digital twins, AI, hybrid approaches, standard statistics and pharmacometrics, as analytical methods and alternative data types and sources such as RWD, eHealth data, registries, historical regulatory submissions, scientific and (non)clinical trials). (3) An AI-based platform that will automate and optimise the data collection, formatting and modelling and simulation analysis and implement the credibility assessment. As part of ERAMET, the ecosystem will be applied to five use-cases including paediatric extrapolation and characterisation of drug benefit/risk in 4 groups of rare diseases, namely ataxia, transfusion dependent haemoglobinopathies, bronchopulmonary dysplasia, and paediatric tuberculosis.Each of the use-case is planned to lead to submission and regulatory approval of at least one validated M&S tool via the EMA qualification procedure.  Training will be proposed to famili
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Concept, design and prototyping of compact sensor nodes using electromechanical impedance and broad band acousto-ultrasonic method for structural health monitoring' in the context of a Seventh Framework call.

assistant: **Objectives**

In the course of the project compact sized, rugged network enabled sensor nodes for monitoring structural health using • Electro mechanical impedance method (EMI) • Broadband acousto ultrasonic method (AU-BB), will be designed (embedded hard- and software) and prototypes manufactured. A cost-efficient but still failure tolerant network interface will enable the sensor node to operate in a heterogeneous multi-sensor environment keeping wiring complexity and thus weight and cost low. The approach respects the high level of EMC that is required in aviation. A first processing of the sensor signal will take place on the node to significantly reduce network load and keeping necessary performance of a data collecting master node low. A dedicated software framework will enable the insertion of automatically generated code.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'On-chip quantum MagNonIcs' (OMNI).

assistant: **Concept**

Quantum technologies allow to harness the fundamental properties of nature for practical applications. An ongoing challenge is the combination of these technologies, to convert between flying and stationary qubit systems, as for example quantum transducer promise. The emerging field of quantum magnonics, dealing with precessional excitations of electron spins at single-magnon power levels, offers the unique opportunity to integrate different quantum systems within a solid-state platform. Although quantum magnonics was theoretically formulated in the 1960’s, only now progress in cryogenics and ultra-sensitive microwave technology allows the first experimental steps. While recent miniaturisation of monocrystalline yttrium iron garnet (YIG) waveguides provides access to propagating single-mode magnons, their use in larger quantum circuits requires the development of different separate building blocks, such as phase shifters, delay lines and attenuators. The project On-chip quantum MagNonIcs (OMNI) is formulated to demonstrate these functionalities on a dynamic on-chip 3-terminal device (3-TD). To this end, I will use the unique magnonics knowledge at the University of Vienna and combine it with my strong expertise in quantum optics, quantum electronics and nanofabrication. The 3-TD YIG device will be designed and modelled numerically, fabricated using modern nanopatterning techniques, and characterized by Brillouin light scattering and microwave spectroscopy at ultra-low temperatures. The device operation will be governed by the magnon dispersion affecting its passage through a non-uniform magnetic field created by an electric current. The successful realization of the project will allow me to demonstrate the required building blocks of Quantum Magnonics and will establish
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Advanced Lasers for Photovoltaic INdustrial processing Enhancement' (ALPINE).

assistant: **Concept**

The aim of the ALPINE project it to push forward the research and development of fiber laser systems for scribing of PhotoVoltaic (PV) modules. The project consortium will focus on a new high brilliance, high efficiency and premium beam quality laser based on photonic crystal fibers (PCFs). The all-around development cycle comprising of the beam source, beam delivery and manipulation, scribing processes, advanced diagnostic and application trials will be demonstrated. The novel laser system will be designed to fit the requirements for scribing innovative and flexible PV modules rather than standard ones based on crystalline silicon wafer. In particular, the two most appealing technological alternatives will be considered, that is CdTe and CIS technology of thin-film solar cells. Validation of the quality process will be assessed. The project joins together the two exciting challenges of the laser development for advanced industrial processing, on one side, and solar energy exploitation, on the other side. Thus it constitutes a crucial opportunity to continue the innovation of European industries involved in material processing applications by employing laser technology and to consolidate PV manufacturing European position. New promising scientific and technological approaches will be investigated. Thus the consortium expects to stimulate the continuous growth of the market in these strategic fields for European development.