RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Entangling Indigenous Knowledges in Universities' (EDGES) under Horizon Europe.

assistant: **Objectives**

Indigenous knowledges are crucial for coping with current global crises, such as climate change, loss of biocultural diversity and rise of xenophobic nationalisms. This pivotal historical moment requires multi-centred thinking and action, bringing together the multiplicity of Indigenous and academic expertise. Universities and academia are critically important in developing knowledge, education, and policy directives. Consequently, EDGES adopts those significant arenas to respectfully advance innovative, collaborative methodologies and new strategies for the entanglement of Indigenous knowledges in research, teaching and policy-making institutions. While there have been efforts to foster dialogue with Indigenous knowledges, these experiences remain elusive, local and not structurally transformative, as the shortcomings of multiculturalism and interculturality have demonstrated. How can we question the existing frameworks and develop new and effective entanglements of knowledges that draw from different epistemologies? EDGES addresses this question through six different analytical layers with the significant participation of Indigenous academic researchers and the active collaboration of Indigenous intellectuals and experts. To accomplish this endeavour, EDGES creates a future sustainable and disciplinary diverse network of more than 150 researchers from 18 European and American universities, one SME and one NGO. The project contributes to a pluralist and multi-scale approach to knowledge production, research and dissemination through symposiums, workshops, mini-courses, open-access scientific publications, policy recommendations and social media. It will provide critical tools for universities, schools and communities to foster critical dialogue with Indigenous peoples
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Dissecting the role of fatty acid oxidation in dendritic cell function and regulation of immune responses.' under Horizon Europe.

assistant: **Concept**

Conventional dendritic cells (cDCs) are pivotal regulators of the immune system capable of tilting immune responses towards effective immunity or tolerance. Over the last 15 years, an increasing body of work has highlighted how changes in the metabolic state of immune cells influence their functions. It has been shown that melanomas can promote cDC tolerogenic functions by augmenting mitochondrial fatty acid oxidation (FAO) via the β-catenin signalling pathway. Intriguingly, recent unpublished results in the host group suggest that boosting oxidative phosphorylation, a metabolic process closely related to FAO, increases cDC immunogenicity. Therefore, further work is required to delineate the relationship between mitchondrial metabolic adpatations and cDC tolerogenic and immunogenic functions.  This action aims to further dissect the interconnection between FAO and cDC functions across different tissues both in steady-state and disease. To this end, I will use novel murine lines that allow for the modulation of FAO in cDCs and will combine classical immunology and biochemial assays to characterise cDCs both functionally and metabolically.  This interdisciplinary approach will help us understand the relationship between metabolism and function in cDCs and how this affects the initiation of immune responses across tissues.


**Keywords:** Immunometabolism, Dendritic Cells, Immune Regulation, Fatty Acid Oxidation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Disrupting X-ray and Short-Wave Infrared Imaging Technology with Quantum Dots' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Medical and consumer imaging face substantial challenges. The highest-resolution Xray detectors use >15-year-old technology, with inadequate image quality yielding unacceptable false negative/positive rates in mammography, especially in dense breast tissue. Meanwhile, short-wave infrared (SWIR) imaging has great commercial potential, but sensors are plagued by high cost and low scalability. QDI has a breakthrough solution to both: our unique, patented process of synthesizing PbS quantum dots of varying sizes into “ink” coatings enables revolutionary X-ray and SWIR imagers. X-ray sensors can reach 5x higher sensitivity than amorphous selenium at low dosage, with >80% high-energy absorption for contrast-enhanced mammography, greatly exceeding current detectors. SWIR sensors can be produced with exceptional speed at low cost, granting novel capabilities to device designers. With EIC support, QDI will transform medical and commercial markets, becoming a European world imaging leader.


**Keywords:** Quantum dots,Quantum dot inks,Semiconductor imaging devices,X-ray detectors,Short-wave infrared sensors
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Stages in the Evolution and Development of Sign Use' (SEDSU).

assistant: **Concept**

There remains, despite centuries of debate, no consensus about what makes humans intellectually and culturally different from other species, and even less so concerning the underlying sources of these differences. The main hypothesis of the project Stages in the Evolution and Development of Sign Use is that it is not language per se, but an advanced ability to engage in sign use that constitutes the characteristic feature of human beings; in particular the ability to differentiate between the sign itself, be it gesture, picture, word or abstract symbol, and what it represents, i.e. the 'semiotic function' (Piaget 1945). The project is highly interdisciplinary and the single research effort will afford new possibilities for methodolog ical innovation, and the collection and analysis of new types of comparative data.The central research objective of the project is to investigate the developmental and comparative distribution of semiotic processes, and their effect on cognition. For this purpose we single out five cognitive domains, and propose to study their interrelations and role in the development of sign use. They are: (a) perception and categorisation, (b) iconicity and pictures, (c) spatial conceptualisation and metaphor , (d) imitation and mimesis and (e) intersubjectivity and conventions. They are all characterised by stage-like developmental profiles which we expect to correlate with differences in sign use. The investigations in the different domains will be carr ied out in parallel, with extensive sharing of methodologies and results. Since we hold that each domain plays a key role in providing cognitive prerequisites for the development of sign use, and at the same time is transformed by the acquisition of the latter, we expect to find considerable similaritie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'In-situ fetoscopic 3D bioprinting for spina bifida treatment' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Currently available pre-birth surgical treatments for Spina Bifida Aperta (SBA) still do not provide a complete recovery in babies and would potentially benefit from a tissue engineering approach, indeed the first clinical trial using stem cells for SBA has recently started, however this is performed via an open-uterus approach. This made me wonder, what if we can develop an innovative system to deliver via fetoscopy a bioprinted tissue engineering costructfor SBA repair? Such an approach would promote tissue regeneration and ease the surgery.In 3D.FETOPRINT I will develop a system for the in-situ fetoscopic bioprinting of a gel composed of extracellular matrix (ECM) proteins and amniotic fluid stem cells (AFSCs) to close the defect of spina bifida aperta (SBA) in a large animal model.The project will be divided into three work packages. First work package will address the development and testing of the gel, by studying the interaction between fetal ECM proteins and AFSCs, to define a gel formulation that could be bioprinted in-utero. Second work package will focus on the design and development of an innovative fetoscopic bioprinting device capable of bioprinting a gel patch on the fetus. Last work package will finally validate the innovative approach. We will first validate through in-vitro testing using a laparoscopic simulator, then we will perform a sheep spina bifida aperta model where the innovative fetoscopic 3D bioprinting system will be vaildated.We will leverage my expertise in biomaterials, cells and tissue engineering device design to carry out this project that will deliver a revolutionary system that will open up the possibility to bioprint tissue engineered constructs on the fetus.


**Keywords:** Tissue engineering, bioprinting, biomaterials
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Towards a unified mechanistic model of oceanic island biogeography' (UNISLAND), addressing dissemination and exploitation.

assistant: **Impact**

Understanding how ecological and evolutionary processes shape patterns of biodiversity remains a central challenge for ecological and biogeographic theory. Oceanic islands, because of their spatiotemporal properties, provide the most promising arena to address this challenge. UNISLAND will advance general theory by applying novel ecological, evolutionary and genomics approaches to explicitly test mechanistic predictions derived from the recently developed General Dynamic Model (GDM). The GDM, while an island focused model, is of broad ecological relevance, because it encompasses generally held ecological relationships, such as the species area relationship (SAR) and the species abundance distribution (SAD). Two key mechanistic predictions derived from the GDM have so far been untested, and are the focus of UNISLAND. The first is that the older an island is, the more old are the single island endemic species (SIEs) that evolved on that island. The second is that single island endemic species (SIEs) have higher extinction probabilities that other species. UNISLAND is embedded in a multidisciplinary framework involving: comparative phylogenetics; community-level modeling; ‘museum’ genomics; and spatially-explicit coalescent-based analysis. Data generated by UNISLAND will evaluate the range shift and extinction risk (species-level and ecosystem-level), thus addressing international and European-level research priorities. Through the collaborative phase between the ER and OPS, UNISLAND will provide the ER with state of the art skills in historical DNA genomics and ecological modelling that will be transferred to the CSIC during the return phase. The complementary research profiles of the OPS, RPS and ER, their mutual interests in the spatial structuring of biodiversity, and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Epistemic protocol synthesis' in the context of a Seventh Framework call.

assistant: **Objectives**

Given my current state of knowledge, and a desirable state of knowledge, how do I get from one to the other? It is possible in principle to reach the desirable state of knowledge, i.e., does it make sense at all to start trying to obtain the desirable state? If I know it is impossible to obtain, there is no use trying. But even if I know that it is possible in principle, is there a way to approach the desirable state in steps or phases, i.e., can I iteratively construct an epistemic protocol to achieve the desirable state? And can this be done with some or with full assurance that I am getting closer to the goal? Such problems become more complex if they involve more agents. The knowledge states of agents may be in terms of knowledge properties of other agents. Such assumed knowledge properties may be incorrect, or the agents may act at unpredictable or unknown moments, or with delayed or faulty communication channels, as typically in asynchronous systems.The focus of much research in dynamic epistemic logic, and more generally in epistemic and temporal modal logics, is analysis: given a well-specified input epistemic state, and some well-specified dynamic process, compute the output epistemic state. In this proposal we focus on synthesis: given a well-specified input epistemic state, and desirable output (typically less well specified), find the process transforming the input into the output. The process found is the epistemic protocol. We will be aided by recent advances in logics for propositional quantification. Areas of specific interest are protocols for secure communication, protocol languages, and agency.Our project goal is epistemic protocol synthesis for synchronous and asynchronous multi-agent systems, by way of using and developing dynamic epistemic logics.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Sustainable Remediation of Radionuclide Impacts on Land and Critical Materials Recovery'.

assistant: **Concept**

The project “Sustainable Remediation of Radionuclide Impacts on Land and Critical Materials Recovery (SURRI)” aims to establish a multinational shared research agenda and project pipeline for addressing the challenges radionuclides pose to land remediation and materials recovery, with a particular focus on rare earth elements (REE) and other critical elements, in order to facilitate more efficient cycling and management of water, soil and material resources. The topic is highly relevant to facilitating the circular use of land, water and several key materials. Investigating the mitigation of radionuclide problems has been rather a “Cinderella” subject for land and waste management research, where the focus has been on organic and inorganic chemical contamination. However, radionuclides present widespread and difficult problems for Society at large and achieving the “Green Deal” in particular. The research concept is based on the integration of electrochemical and microbiological interventions, which can be applied, in-situ or ex-situ, to provide new tools to unlock the remediation of radionuclide affected sites, and facilitate the recovery of material resources from radionuclide-impacted wastes, and so reduce reliance on virgin (and non-EU) sources.The project is coordinated by the TECHNICKA UNIVERZITA V LIBERCI (TUL, CZ) with the participation of the UNIVERSIDAD DE GRANADA (ES), UNIVERSITA DEGLI STUDI DI ROMA LASAPIENZA (IT) and the UNIVERSITY OF SOUTHAMPTON (UK, Associated Partner). The three internationally leading partners in the field will help TUL to reach five specific objectives – to advance its research excellence in radionuclide impact mitigation, to develop a shared research vision and supporting research agenda for a virtual R&I centre, to raise the research
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Adding Value to Holy Grain: Providing the Key Tools for the Exploitation of Amaranth the Protein-Rich Grain of the Aztecs' to be submitted under Sixth Framework.

assistant: **Abstract**

The immediate objective of this project is to provide the tools for an extensive and sustainable exploitation of amaranth. The project will contribute to the overall development objective of providing health-promoting food and exploiting the industrial use of amaranth and thus provide a source for income in regions of the world, where the warm and dry climate makes the cultivation of amaranth the obvious choice.The effects of food on human health are central issues both in Europe and in Latin America. Malnourished children and adults living in rural areas need much better access to protein-rich food supply. Amaranth grains and leaves are protein-rich and have a good balance of essential amino acids. Amaranth is a C4 plant, resistant to drought and heat. Strong efforts have been done by for instance FAO, in retrieving and disseminating the knowledge of amaranth cultivation However, a range of still not solved problems for the sustainable use of amaranth exist.Modern technologies have become available to researchers both in Europe and Latin America. With these tools the properties of amaranth species can now be elucidated with the purpose of targeted breeding of new varieties and thus improving the basis for amaranth cultivation and exploitation, - for achieving food security and for industrialized exploitation. We will perform a systematized study of the industrial exploitation of individual amaranth constituents; evaluate the health effects on humans and animals of amaranth based food; identify genes and gene complexes responsible for resistance to insects, fungi, drought and salinity and select varieties with high competitiveness.Amaranth genotypes will be cultivated in varying sites and monitored. Multivariate statistical analysis will be applied to the generated data
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Affective Polarization and Democratic Attitudes', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

We currently witness democratic backsliding around the world where political rights, civil liberties, and free and fair elections are under assault. At the same time, politics in many countries are increasingly characterized by hostility and distrust across partisan lines; a phenomenon called affective polarization. Could there be a causal link between the two? Despite several theoretical conjectures about how affective polarization erodes democracy through its negative effects on citizens’ democratic attitudes, we lack the evidence to support them. We also do not have reliable interventions to reduce affective polarization that are generalizable to different contexts.DEPOLARIZE addresses these puzzles around affective polarization with two objectives. First, it will identify reliable and generalizable experimental interventions to reduce affective polarization in multiple contexts. Second, it will establish any causal relationship between affective polarization and changes in democratic attitudes through novel empirical approaches.DEPOLARIZE will achieve these goals by producing and analysing high-quality observational and experimental data from multiple waves of surveys in Hungary, Poland, Turkey, and the US. These countries are selected for analyses because they have recently experienced democratic backsliding to different degrees, and they are also examples of high levels of affective polarization in society.The stakes for identifying factors contributing to democratic backsliding could not be any higher. DEPOLARIZE will contribute to this effort by establishing whether affective polarization is a factor driving democratic backsliding using state-of-the-art causal inference methods. DEPOLARIZE is also one of the first projects in political science to employ comprehe