RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Cases acquisition and reply in fire campaigns ambience' under Fourth Framework.

assistant: **Concept**

The CHARADE project (Esprit 6095) developed a system that enables firemen to save time spent on evaluating forest fire emergencies and resource engagement, thus saving lives, equipment and money.However the system has not been tested during a real fire situation. Potential users therefore are not yet confident of its performance capability in large scale situations or its suitability to their operational needs (e.g. 24 hours a day, 7 days a week).The French South East Inter-Regional Centre of Operational Coordination of the Civil Security (CIRCOSC) and the French International Training Centre of the Civil Security (CIFSC) have agreed to experiment with a tailored CHARADE system in shadow mode.The aims of the CARICA project will be to demonstrate in an experiment the suitability and the benefits of the case-based reasoning (CBR) technology introduced in CHARADE, and to show its ability to support intervention planning. This project will adapt the CHARADE demonstrator for the French organisation and the results evaluated, to enable enhancement and tuning from a real context. The objective will be to ensure that it will be ready to run in a real mode for the 1996 fire campaign. The CARICA system will provide firemen with a tool to populate a Forest fires interventions" database which will be accessed by trainees to increase their knowledge by auto education, by firemen to study or debrief forest fires intervention, and by trainers to build exercises based on real emergencies.If the system demonstrates its capacity in a real mode in 1996, it will be deployed in the South of France "Départements". It will also be used at the CIFSC where firemen, coming from various Mediterranean countries, will learn how to use it and be able to export the knowledge back to their respective
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Examination and structural characterization of paramagnetic metalloproteins via multinuclear and multidimensional nmr-techniques 5' in the context of a Fourth Framework call.

assistant: **Objectives**

Proteins are responsible of a very large number of biological functions in living systems. Among them enzymes are the catalysts in biological sytems. Their properties are strongly affected by their three-dimensional structure. Enzymes often contain transition metal ions which are involved in the reaction catalysed by the enzyme. The understanding of the functional behaviour of enzymes is linked to the knowledge of their three-dimensional structure. There are different methods to analyse the structure of enzymes, by single crystal X-ray structure analysis or by multidimensional NMR techniques using the NOEs. The NMR analysis provides the structure of the proteins in a medium of biological interest, dissolved in water. The NMR analysis normally only allows the characterization of small enzymes. In nature there are a lot of enzymes which contain paramagnetic transition metals in their active site. The paramagnetism of these enzymes, even if they are large, allows the study of the active site of these enzymes via the paramagnetic shift in their obtained NMR spectra. Targets of the project are the structural determinations of paramagnetic metalloproteins as cytochromes containing one or more iron atoms or at least to get a view of their active sites using multidimensional NMR techniques. The change of the oxidation state of the transition metal atoms in the enzymes may cause differences in their solution structure which may be determined using these methods. So it should be possible to understand the functional behaviour of these redox active enzymes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Linking livestock genetic diversity with three thousand years of agricultural crises and resilience' under Horizon 2020.

assistant: **Concept**

Over the last 50 years, chicken production has increased fivefold, chicken growth rate has tripled, and milk production per cow has doubled. Yet, many of the biotechnological tools responsible for this accelerated trend are now under threat of becoming obsolete. While the causes are numerous, one significant driver is a dramatic reduction of genetic diversity in livestock populations.Cycles of agricultural productivity growth and decline have occurred throughout European history, spurred by major historical forces such as the spread of empires and continent-wide epidemics. For example, productivity crashed between the 4th-13th centuries, only to rebound during the Agricultural Revolution of the 13-18th centuries. Fluctuating levels of genetic diversity were likely both cause and remedy to these cycles. Genetic diversity acts as a fuel for selection: the lower it is, the more difficult it is to improve traits, and the more likely that epidemics will develop and spread. Given this importance, maintaining diversity amongst livestock is recognised as one of the UN’s Sustainable Development Goals. Despite this, we lack any understanding of how much genetic variability was present, and subsequently lost, before, during, and after either the Green or Agricultural Revolutions, nor do we understand how efficiently it was utilised. PALAEOFARM will assess the long-term sustainability of modern breeding practices by unravelling how genetic variability was leveraged across major agricultural transitions in European history. Using an innovative combination of ancient DNA, archaeozoology, and experimental immunology, I will explore how livestock populations withstood epidemics and selective breeding in a world without antibiotics or quantitative genetic techniques. This will provide a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Detailed prospecting in dead-reckoning in insect navigation'.

assistant: **Concept**

Research objectives and content Dead-reckoning is one of the principal navigational strategies employed by insects to reach a familar place. The animal has an internal vector which defines the distance and direction of the goal from its starting point This vectorial information is either computed on line" through path integration during the previous journey from goal to starting point or it is recalled from long-term memory. On a journey controlled through dead-reckoning the insect uses biological compasses lo adjust its path. However. the details of moment control are not well understood. Part of the proposed project is to investigate in detail how ants use celestial and magnetic compasses in guiding their journey. We will also investigate the use of visual scenes in . the recall of memorised movement vectors. Lastly. we will investigate the path integration strategies that ants use when foraging within a complex environment. Is just a single record made Or the outward path or do ants divide the path into sequence of vectors? Training content (objective, benefit and expected impact) The aim of the project is a better understanding of dead-reekoning at a behavioural and a computational Ievel. Although of great importance in navigation and much studied there remain many uncertainties. Our ultimate aim and that of many other laboratories is to understand navigation in sufficient detail that robots can be constructed which will navigate with the precision and flexibility shown by insects. The increased understanding of dead-reckoning obtained in this project should contribute to this endeavour. Our ultimate aim and that of many other laboratories is to understand navigation in sufficient detail that robots can be constructed which will navigate with the precision and flexi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Coordinating and synchronising multimodal transport improving road, rail, water and air transport through increased automation and user involvement' (ORCHESTRA) under Horizon 2020.

assistant: **Objectives**

The long-term vision of the ORCHESTRA is a future where it is easy to coordinate and synchronise the traffic management of all modes to cope with diverse demands and situations. Also, to facilitate optimal utilisation of transport networks and efficient multimodal transport services, both in rural and urban areas.The project will:* Establish a common understanding of multimodal traffic management concepts and solutions, within and across different modes, for various stakeholders and multiple contexts* Define a Multimodal Traffic Management Ecosystem (MTME) where traffic managements in different modes and areas (rural and urban) are coordinated to contribute to a more balanced and resilient transport system, bridging current barriers and silos* Support MTME realisation and deployments, through the provision of tools, models, and guidelines - including support for connected and automated vehicles and vessels (CAVs)* Validate and adjust MTME for organisational issues, functionality, capability, and usability* Maximise outreach and uptake of project results through strong stakeholder involvementThe project will provide a Polycentric Multimodal Architecture (PMA) that specify how diverse system components collaborate and interact, taking into account smart infrastructures, technical and organisational aspects and polycentric governance. The PMA will be supported by: 1) Enabling toolkit, 2) Deployment toolkit, 3) Documented lessons learned. The project will validate the PMA and related tools and toolkits in two Living labs (in Norway and Italy), collectively covering both road, rail, water, and air transport. The Italian Living lab is focusing on traffic orchestration for the mobility of people, while the Norwegian Living lab is focusing on traffic orchestration for freight.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'New technology and pilot process for recycling residual packaged fo od products for producing high-quality dry pet-foods' in the context of a Fourth Framework call.

assistant: **Objectives**

The project objectives are: Development, constructin and validation of an unpacking pilot process, to separate the package (bottles, glasses, tins, bricks, paper cardboard, and plastic covers) from the following by-products to be recycled, without altering their nutritional characteristics, specially their freshness: Products that have passed the expiry date = the sell-by date". Products from mistakes in production. Products from mistakes in marketing. Products rejected by quality control or with broken packaging, etc. Products that are daily collected by bread manufacturers in the supermarkets. (Fresh bread not sold). The main problem for unpacking operations is the enormous diversity of by-products and materials. Development, construction and validation of the adequate pilot equipments to prepare, dosify and mix the dry and semimoist by-products to be recycled. Development, constructin and validation of a extrusion pilot process, including the injection process of "cream of fresh meat" to obtain, from the by-products, the following final products: High protein pellet pet-food, 72% of total production. Pet-food as a compound ingredient, 9% of total production. Semi-manufactured compound food (to pigs), 11% of total production. Manufactured compound food 4% of total production. Final compound food, 4% of total production. The main problem is the variation in final products composition, which must be limited to the 2% for every ingredient. The production rate will be as an average 1.42 Ton/hour (1.6 Ton/hour dog-food, 1.25 Ton/hour cat-food). The research approach to be followed can be summarised as follows. First, an unpacking pilot process will be developed, which will be constituted by a line of machinery with one common head. After, a recycling pilot process will be
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Piloting RRI in Industry: a roadmap for tranSforMAtive technologies' under Horizon 2020.

assistant: **Concept**

There is now only limited experience with RRI in industry and there is also limited evidence of the added value of opening up the innovation process in industry for social engagement and gender considerations. We will overcome these current limitations by carrying out eight RRI pilot projects in a real-world industry context. To establish the added value of the RRI approach and the gender dimension in and for industry, we will assess the pilot projects on a number of product and process RRI dimensions and compare the score of the pilots on the relevant RRI dimensions with the score of similar projects in the same companies in which the RRI approach has not been followed. We focus on implementing RRI for some of the major technological challenges in the EU including nanotechnology, synthetic biology, Internet of Things and self-driving or automated cars. These are all transformative technologies that have the potential to transform existing modes of production and to change the relation of the company with users, suppliers or other stakeholders. The pilots aim at integrating RRI in the CSR (Corporate Social Responsibility) policies of the participating companies. Some pilots will take place in private companies and some in public-private partnerships (PPPs). The project will be supported by extensive stakeholder consultations and dialogues. These will feed into the set-up and the carrying out of the pilots. The project will result in a RRI-CSR roadmap for transformative technologies. The roadmap will be widely disseminated through  the partner’s extensive industry network, and through industry branch and CSR organizations. An important means of dissemination will also be the MOOC (Massive Open Online Course) on RRI in industry. The dissemination is expected to lead to a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'INNOPAX - INNOVATIVE PV INTEGRATION IN EXISTING BUILDINGS IN DK, IT AND NL' to be submitted under Fourth Framework.

assistant: **Abstract**

For substantial electricity production by PV in Europe, grid connected systems in the built environment will become a necessity. Besides integration of PV in future new houses and commercial buildings there is a gigantic potential for the integration of PV in existing buildings. It is essential that the PV panels will be integrated architectural to convince the building market that PV is a real building product for high quality buildings of aesthetically value. For the introduction of these systems, further development of building elements and building concepts are needed. In this project several innovative architectural integration techniques for existing dwellings and commercial buildings will be demonstrated.Next to a higher acceptance by the building market a price reduction has to take place before PV systems will be used on a large scale for energy production. Therefore it is necessary that the PV systems have more functions than only the production of electricity. In this project PV elements are used as fully grown building elements, with aesthetical aspects and thermal or daylighting qualities.The project will also demonstrate how local authorithies and utility companies can contribute to the introduction of the market for PV-projects in Europe and they are in good position to affect the users. In short the aims of this project are to demonstrate to builders and architects the high quality and high diversity of integration techniques that are possible with PV panels for existing buildings and to demonstrate the advantages of multifunctional PV systems in northern and southern Europe.The proposal covers building integration of PV-modules in five building projects, two in Denmark, two in The Netherlands and one in Italy. A total of 90 kWp will be installed.DENMARK
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Polyomavirus pseudocapsids as vectors: applications for genetic and immunological therapeutic purposes of modified VP1 pseudocapsids' in the context of a Fourth Framework call.

assistant: **Objectives**

In recent years it has become common practice to use viruses in the development of new methodologies for improving strategies useful to human health. The knowledge of the genetics and biology of viral-host interactions, as well as the establishment of the structural configuration of the viral particles, has proved pertinent in validating the system adopted. One of the best studied viruses is the oncogenic murine virus polyoma (Py). Two of its characteristics render it a favourite object of study: the shortness of; its DNA genome (5296 bp) that encodes only three early and three late proteins and the advantage of having mouse, genetically the best analysed mammal, as its natural host. ! the three early genes code for multifunctional proteins that control the interaction with the host cells and regulate transcription and replication of the virus. The three late proteins form the capsid in which the viral genome is packed. VP1 is the major of these three proteins in size and in relative amounts (85%) in the mature capsid. Its' role was considered, until very recently, as mainly structural. Its three dimensional structure has been determined, as well as that of the mature capsid. VP1 forms pentamers in-vivo and can polymerise to form ``infectious'' pseudocapsid structures, as has been shown by one of the participating groups. Mutations in VPl have been selected which display tissue specific modified host range of growth and degree of tumorigenicity in-vivo (point mutation) or with altered host range in-vivo and in-vitro (amino acid deletions). The deletion of these latter mutants (selected by one of the participating groups) involves the D-E loop of the protein. This loop is exposed in the outer face of the viral capsid and is highly antigenic. The genetic analysis of these
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Development of scalable microfluidic device for drug testing using humanized adipose tissue spheroids' (SMD-SPH) under Horizon 2020.

assistant: **Objectives**

In regenerative medicine, in vitro tissue engineering products (3D cell cultures) for in vivo therapy are critical for more accurate and more humane medical innovation. Tissue engineered scaffold-free 3D models that exhibit functional hallmarks of native tissues improve our search for biomarkers, drug testing/development and toxicology with more accurate models, while supporting the development of alternative methods to animal use in drug testing, as stated by the Directive (2010/63/EU) established the European Centre for the validation of alternative methods (ECVAM). To replace animal testing, it is important to develop microphysiological systems and ‘body-on-chip’ approaches that allow to account for organ-to-organ interactions in vitro, at a reasonable cost. Yet, most current bioreactors are expensive, designed for organ transplant (thus focused on a single organ) and poorly designed for miniaturization and scale-up. In SMD-SPH, we will develop a microphysiological systems with the following design requirement: a 3D cell culture model, with a continuous and controllable perfusion system for continuous contact with morphogens (growth factors) to obtain a functional native tissue and  monitoring crucial parameters of cell physiology, compatible with scale-up manufacturing. To the best of our knowledge, it is the first time in scientific literature that human adipose tissue-derived stem cells are used to build human white adipose tissue in a novel and scalable microphysiological system. This project meets the convergence of microfluidics and scaffold-free 3D culture models offering a reliable alternative for drug and toxicology assays, besides offer a scalable and reproductible system for future integration into a human-on-a-chip and high-troughput assays. Once an initi