RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'A european consortium for participation in the ideal project (EURO-IDEAL)' to be submitted under Fifth Framework.

assistant: **Abstract**

To strengthen and consolidate the position of European science within the IDEAL (International Decade for the East African Lakes) project, we propose the establishment of a consortium (EURO-IDEAL) of European scientists engaged in IDEAL-related research. Results from the IDEAL project are of global significance, particularly in the fields of global change, human impact on the environment, and biodiversity. EURO-IDEAL will provide a forum for contact between European participants in IDEAL and an avenue for the coordination of their present and future activities with those of the North American and African participants in the project. Contact within the consortium will be achieved through a series of workshops, the creation of a EURO-IDEAL website, and exchange visits between individual scientists pursuing related research problems.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Care work in europe: current understandings and future directions' to be submitted under Fifth Framework.

assistant: **Abstract**

The subject of this proposal is care work: important across both member and accession states. It has the potential for cross-national exchange of knowledge and best practice; is highly relevant to the economic social and demographic concerns of the EU and has a direct bearing on the welfare, empowerment, lifelong learning and social inclusion of citizens. Its main objective is the generation of a pan-European approach to good quality, responsive employment. The proposal will principally address research task 3, but will also make a substantive contribution to research tasks 2 and 5. The study will use a partnership of five member states and one accession state to investigate care work using a range of both innovative and established research methods: comparative review of statistical and research literature; case studies of occupational groups; and an extensive dissemination programme including evidence of innovative practice, national, and west and east European seminars, and a website.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Integrated cyber-physical solutions for intelligent distribution grid with high penetration of renewables' under Horizon 2020.

assistant: **Concept**

UNITED-GRID aspires to be the arrow-head within “Integrated cyber-physical solutions for intelligent distribution grid with distributed energy resources” and addresses the challenges in the “competitive low-carbon energy"", relevant to next generation of active distribution grids.UNITED-GRID will develop a tool-box with technologies enabling at least 80% renewable-based energy production on an annual basis, with an increased reliability performance of 50%, while decreasing grid losses by 10%. The developed technologies include e.g. solutions for real-time system awareness and control, short term generation and load forecasting, setting-less protection schemes and new business models. The tool-box will be integrated into a professional system ensuring interoperability and smooth integration with existing EMS/DMS on the market. To enhance future impacts, at least 2/3 of novel solutions which have been positively validated will have an agreed and financed development processes for the next TRL level beyond the project.The project team has been selected carefully and has proven R&I, demonstration and deployment capabilities as well as established regulatory and policy channels. The team includes experienced research organisations (SP, TU/e, CEA, and Chalmers), 3 DSOs, a DMS provider and expert SME partners to ensure the exploitation of the developed solutions. To further enhance the deployment towards a low carbon energy society, the project will together with at least 20 market actors define pathways to navigate in the rapidly changing energy environment. Furthermore, at least 25% of the test-pilots will sign a letter of commitment to execute parts of the developed pathways. The real-life demonstrators, covering more than 80% of European market conditions, are provided by
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Product tracking for the textile dyeing finishing and printing processes' (1994-1998) under Fourth Framework.

assistant: **Objectives**

The project goal is to prototype a system for tracking in real time the products in the factory plant and to build a demonstrator vithin a textile factory . Suitable tags with the correspond readout units connected to the information system. The tags must resist all the process hard environment conditions ot' the dyeing process- chemical corruption. high temperature. mechanical stresses.... A typical Dye. Finishing and Printing company works with: a lot of different clients: a lot of different kinds of fabrics: different procedures to take in the same process. So, this kind of enterprise has to be well organised. to avoid delivering a fabric to the wrong client or to make different from the requested. Presently the Product Tracking in the dyeing, finishing, and printing processes does not exist. The usual way to know the production state is through the production orders. This project will develop a technology adapted to the needs of the textile dyeing, finishing and printing SME. due to the fact that it will help them to decrease significantly the production costs in small orders. and increase productiveness. A better production organisation will help SMEs to produce less waste and substandard materials. it will also help to speed up the process. These factors are of particular relevance in the production of many small series.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Institutional Discrimination in (Explicit) Action: How Policies Shape Inequalities' (Explicit), addressing dissemination and exploitation.

assistant: **Impact**

This research project explores the consequences of institutional discrimination, i.e., discriminatory treatment of individuals (based on their membership to a certain group) perpetuated by organizations. In particular, the project explores two policies that created institutional discrimination, and aims at causally estimating the impacts on the socio-economic outcomes of affected individuals. In order to causally estimate the effects of institutional discrimination, I will make use of rich administrative data from the Netherlands and exploit quasi-random variation in exposure to institutional discrimination, induced by the Dutch institutional context. In the first work package, I will use a combination of rich administrative data, machine learning methods, and a difference-in-differences research design, to study the effects of the Dutch childcare benefit scandal. This scandal arose when the Dutch tax authorities started to target fraud investigations (and heavily punish even small administrative mistakes) using an algorithm that was biased against individuals with a non-Dutch nationality. In the second work package, I will use rich Dutch administrative records matched with unique data from the social housing corporation in Rotterdam, and a difference-in-differences research design, to study the effects of the Rotterdam Act. This Dutch policy created institutional discrimination by prohibiting access to social housing to some groups of individuals in disadvantaged neighbourhoods. Both studies will investigate the effect of institution discrimination on a wide array of socio-economic outcomes, including labour market participation, welfare receipt, wealth, health, and criminal involvement. The results of this project will be of interest to a wide audience as they will co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Design and Chemical Construction of Quasi-living Phagocytic Synthetic Cells for Artificial Phagocytosis of Bacteria' (PhagoSynCell) under Horizon Europe.

assistant: **Objectives**

The growing occurrence of antimicrobial-resistant infections, compounded with the stalling development and approval of new antibiotic drugs, has created a therapeutic gap, threatening a global health crisis. Resistance emerges when bacteria mutate their molecular targets for antibiotics, evading their action. Is it conceivable to design synthetic cells assembled from abiotic synthetic macromolecules, capable of mimicking the most salient features of phagocytosis —Nature’s most selective, effective, and advanced strategy to eradicate pathogens? The aim of PhagoSynCell is to create Phagocytic Synthetic Cells (PSCs) that selectively recognize, capture, engulf and kill antibiotic-resistant bacteria without generating selection pressure for resistance. Firstly, we will develop the membrane of the PSCs by the simulation-aided synthesis of novel macromolecular amphiphiles (Janus dendrimers and amphiphilic comb polymers) self-assembled into vesicle libraries with functional diversity and phenotype programmability. We will then study novel methods to facilitate engulfment of micro-objects by leveraging principles of mechanical actuation programmed at the molecular level. We will introduce superselectivity to artificial membranes to selectively capture bacteria. Furthermore, we will develop an antimicrobial strategy triggered and activated by engulfment that disrupts the bacterial membrane —an element highly unsusceptible to evolution. Finally, we will demonstrate the efficacy of PSCs against pathogenic antibiotic-resistant strains and show their biosafety in cells, organoids, and advanced tissue models as proof-of-concept for future applications. PhagoSynCell will unveil the underlying principles of Artificial Phagocytosis, delivering synthetic cells able to selectively recogniz
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Environmental typomogical space facilitating the implementation of European legislation.' (APERTURE) under Fourth Framework.

assistant: **Objectives**

APERTURE aims at developing a cost-effective methodology to categorise and map various areas of Europe according to International, European and National Environmental Legislation. The outcomes of the APERTURE will be employed to (i) reduce the infringement related to Environmental Legislation and (ii) increase the awareness of policy makers, scientists and environmentalists about the potential value of Earth Observation (EO) data in developing and applying international, European and National environmental law. The project will investigate in four Pilot European sites if and how merged VHSR (Very High Spatial Resolution) and HSR (High Spatial Resolution) EO data as well as new impending satellite systems (i.e. Space Imaging, EarthWatch) can be utilised in judicial or extra judicial proceedings concerning the implementation of environmental laws. The project will set up guidelines and specify standards with respect to spatial and spectral resolution of EO data so that these can be used by the European Court of Justice, Legislators, National Administration and Courts as evidence to support their decisions in given cases. The present Pilot project employs and integrates PROVEN state-of-the-art technologies such as: (1) Digital Image Processing and Interpretation of merged VHSR and HSR EO data or a combination and synergy of data from different space platforms to derive the most efficient means of: (a) obtaining information on land-use conditions and (b) detecting time-changes on those conditions, (2) Use of Geographical Information Systems (GIS) for multi-layer information storage and processing, (3) Global Positioning Systems (GPS), (4) Graphical Modelling. An extensive analysis of the International, European and National Environmental Legislation will be performed. The o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Augment your pension - How Augmented Reality (AR) can improve future financial well-being: The role of future self-imagery and its impact on pension awareness and engagement' under Horizon 2020.

assistant: **Concept**

Elderly poverty is a prominent problem, and financial well-being in elderly is often considered low. A common cause for elderly poverty is a lack of sufficient pension awareness and engagement, especially at a young age. Independent of the pension scheme in a particular country, pension funds and policymakers around the world struggle to increase the engagement of pension plan consumers that would affect a consumer's future financial well-being positively. An often-proposed intervention to overcome the present bias that leads to not engaging with pension communications is to stimulate the imagery of the future self in pension plan consumers. Yet, current pension communications fall behind expectations in stimulating imagery of the future self and thus fail to improve pension awareness and engagement. In light of recent evidence on a new technology coined Augmented Reality (AR), this project proposes an experimental approach to investigate the impact of AR on the imagery of the future self and the downstream effects on pension awareness and engagement. Building on a series of laboratory, online, and field experiments, I apply findings from recent AR research in consumer behavior to find evidence and theoretically explain the effects AR can have on pension awareness and engagement. Combining findings from laboratory studies with field-evidence from the world’s third largest pension provider (APG) will shine light on how to improve pension communication with AR to improve future financial well-being. The proposed results are societally relevant as they can help to promote pension engagement that results in future financial well-being. My strong background in experimental consumer behavior research with a focus on AR technology and consumer engagement, combined with my supe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Design and Exploitation of C-C and C-H Activation Pathways in Asymmetric Catalysis' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Synthesizing organic molecules in high purity with designed properties is of utmost importance for pharmaceutical applications and material- and polymer sciences including the efficient production of enantiopure compounds and the compliance with ecological concerns and sustainability. The efficiency of all reaction classes has improved over the past decades. However, the basic principle and execution did not change: The target molecule is disconnected into donor and acceptor synthons and appropriate functional groups need to be introduced and adjusted to carry out the envisioned coupling. These additional steps decrease the yield and efficiency, are costly in time, resources and produce waste. The introduction of new functionalities by direct C-H or C-C bond activation is a unique and highly appealing strategy. The range of substrates is virtually unlimited, including hydrocarbons, small molecules and polymers. Such  dream reactions  avoid any pre-functionalization, shorten synthetic routes, make unsought disconnections possible and allow for a more efficient usage of our dwindling resources. Despite recent progress in the activations of  inert  bonds, narrow scopes, poor reactivities and harsh conditions hamper most general practical applications. Especially, enantioselective activations are a longstanding challenge. The outlined project seeks to address these issues by the development and exploitation of new catalytic enantioselective C-H and C-C functionalizations of broadly available organic substrates, using chiral Rh- and Pd- catalysts, additionally supported by automated screening and computational techniques. These reactions will be then applied in the streamlined synthesis of pharmaceutically relevant scaffolds and of compounds for organic electronics.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Macrophage blockade for the improvement of targeted radionuclide delivery to malignant tumours'.

assistant: **Concept**

The aim of RADBLOCK is to improve nanocarrier-based radionuclide delivery by enhancing targeting and overcoming problem of non-specific uptake of nanoparticles by macrophages in liver and spleen. For this purpose, two approaches will be used simultaneously: 1) modification of radionuclide-loaded nanoparticles with targeted scaffold proteins, recognizing HER2 receptor expressed by malignant cells; 2) temporal blockade of the cells of the mononuclear phagocyte system (MPS) to decrease elimination of the nanocarrier. The results of the project will be beneficial to the diagnostics and treatment of tumours with overexpression of HER2 receptors, such as human breast and gastric/gastroesophageal carcinomas. This project is novel and innovative, since presents first application of macrophage blockade technology for improving of radionuclide delivery with nanoparticles. RADBLOCK is a multidisciplinary project and combines modern chemical methods of nanocarrier preparation, physical methods for the material analysis and its comprehensive biological evaluation at the animals, bearing human xenografts. The applicant will conduct research in Uppsala University under supervision of Prof. Vladimir Tolmachev, expert in radiopharmaceutics and clinical applications of targeted scaffold proteins. As a two-way knowledge transfer fellow will be trained in methods of radiochemistry and radiopharmaceutics and will bring experience with nanomaterials chemistry and macrophage blockade techniques to the host organization. RADBLOCK is expected to increase radionuclide blood bioavailability in mammals and enhance specific tumour delivery, which will have positive effects on targeted diagnostics and therapy of malignant tumours with radionuclides.


**Keywords:** Nanoparticles; Radionuclides; Drug
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'THE ROLE OF ELASTASE/ELASTASE INHIBITOR IN DIALOG BETWEEN INTESTINAL EPITHELIAL CELLS AND MACROPHAGES IN INFLAMMATORY BOWEL DISEASES CONTEXT', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Inflammatory Bowel Diseases (IBD) are chronic disorders for which aetiology is unknown and only palliative care is available for patients. In Europe, 2.2 million people suffered of ulcerative colitis or Crohn's disease in Europe, the socio-economic impact of IBD is very heavy. Thus, the development of new and more effective treatments for IBD depends upon a better understanding of the regulation of inflammatory response.The aims of this project are both:  firstly, provide evidence of contribution of secreted elastase from intestinal epithelial cells (IEC) to over activation of macrophages in IBD and establish molecular actors of this crosstalk; secondly decipher the protective properties against colitis of ELAFIN, an elastase inhibitor, through modulation of macrophage activities. The fellow will develop in vitro and in vivo experiments to establish the role of elastolytic balance in the dialog between IEC and macrophages in relation to IBD.Our data raise the possibility that intestinal IEC are major regulators of proteolytic homeostasis by secreting proteases and protease inhibitors, which then can interfere with all biological functions of the gut, including immune functions. In IBD, secreted hyperactive elastase could participate to the dialogue between epithelium and other mucosal cells such as macrophages. Our analysis of elastase homeostasis aims to identify control points in the mechanisms of disease that could be addressed by development of a novel therapeutic approach for IBD.The fellow holds a junior investigator position at a French Institution. This program will allow her to develop complementary and transferable skills and to successfully build-up and conduct a ground-breaking research project in the field of human digestive health. This foreign experience