RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Linking living plant traits to soil biogeochemical functions in ecosystem patches under different land use regimes using an isotope-based assessment'.

assistant: **Concept**

Nitrogen cycling is an important aspect of ecosystem functioning and global change. Plants affect soil N cycling through a series of direct and indirect mechanisms. It is therefore essential to understand how human-induced shifts in plant communities modify soil N cycling. One emerging approach to assess these links is by expressing vegetation data based on the functional characteristics (‘traits’) of the plants that make up an ecosystem. In this study, four different land use patches under different historic and present land management within a regional landscape will be selected, and characterized according to their plant functional diversity. Living plant, but not soil effects, on gross N cycling and microbial community structure will be determined using root-permeable cores filled with a common soil, and installed in the land use patches 9-15 months prior to isotope-based N cycling measurements. Statistical RLQ analysis will be used to investigate links between plant traits and biogeochemical ecosystem functioning. The innovative nature of this project lies in the combination of state-of-the-art methods and concepts in plant ecology and biogeochemistry that complement each other in a multi- and interdisciplinary framework. This is achieved by integrating expertise of two research institutions that share a common research interest in global change ecology, but each have a very different conceptual and methodological background in the complementary scientific subdisciplines of plant ecology (outgoing host) and biogeochemistry (return host). The proposal contains a 2-year training period to learn and apply the use of plant trait approaches at one of the worldwide leading institutes in trait-based ecology (Multidisciplinary Institute of Plant Biology, Córdoba, Argentina
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Intelligent power management integrated circuits for a greener, more efficient Internet of Things' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The Internet of Things (IoT) offers great potential to monitor and manage complex systems, yet remains hindered by excessive use, size, and replacement of batteries in IoT nodes. Decreasing power use is essential to fulfil the IoT promise for smart, sustainable, and green societies. We have developed a unique Intelligent Power-Management Integrated Circuit (IPMIC) using silicon-proven subthreshold technology that can autonomously manage any sensor, microcontroller, wireless chip, or peripheral to reduce energy consumption by ~50-99%. This grants novel capabilities to all designers of battery-powered devices to optimize for increased performance and reduced product size/cost, while eliminating replacement cost/operational barriers for new applications in critical parts of the value chain and environmental impacts of disposal. With EIC support, Nanopower will address the IoT battery bottleneck and become a Europe-based, world-leading ultra-low-power specialist.


**Keywords:** Energy efficiency; Environmental and green technologies; Internet of Things, embedded/pervasive systems; Network infrastructures; Micro (system) engineering; Semiconductors
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'MARKET ENABLING INTERFACE TO UNLOCK FLEXIBILITY SOLUTIONS FOR COST-EFFECTIVE MANAGEMENT OF SMARTER DISTRIBUTION GRIDS' under Horizon 2020.

assistant: **Concept**

The present context shows the potential of electricity grids to lead the energy system transition as long as new solutions deal with the challenges related to flexibility solutions, grid observability and controllability, market mechanisms and interoperability in a holistic way. The new solutions need to cover the technological aspects by linking smart and integrated services and tools for distribution grid with market mechanisms. This architecture will guarantee a significant impact on the environment and society.  The project consortium accepted this challenge and will develop “EUniversal Project” which will enable the transformation of the electricity grid by resolving existing limitations in the energy system through the introduction of a Universal Market Enabling Interface (UMEI). Through this concept, grids will become capable of accommodating all future scenarios through the active use of grid services, acting as an extensive toolbox of flexibility solutions and innovate market mechanisms. The primary goal  of EUniversal is to enable the transformation of the energy system into a new multi-energy and multi-consumer concept guaranteeing a sustainable, secure and stable manner of electricity supply by bringing forward an universal, adaptable and modular approach through a Universal Market Enabling Interface (UMEI) to interlink active system management with electricity markets and the provision of flexibility services, taking also into consideration the activation needs and the coordination requirements with both commercial parties and TSOs. To do so, EUniversal will define, develop and validate a set of market-oriented flexibility management services from DER in a real environment, under a large RES integration and high electrification scenario.In order to demonstr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Desertification in the Mediterranean drylands - development of a monitoring system based on plant ecophysiology' under Fourth Framework.

assistant: **Concept**

The main objective of the project is the control of the desertification processes in some edge ecosystems of Turkey and Lebanon (overgrazed pastures, overcultivated or abandoned lands, coastal vegetation, etc.) by means of environmental monitoring based on the following :* To record and analyse the ecophysiological indices of typical vegetation (leaf water potential, xylem cavitation, CO2 absorption and photosynthetic efficiency, transpiration rate and water balance, etc.) in the Mediterranean drylands, by means of advanced field techniques.* To develop numerical models with advanced methods (landscape-oriented models, GIS, remote-sensing) for assessing the dynamic evolution of these parameters, producing synthetic indicized informations on the state of the environment related to drought stress.* To define control systems of the degradation of the Mediterranean drylands vegetation types, detecting the major vulnerability areas to help in making decisions for land management plans.Expected OutcomeThe most important results should outcome into the definition of new methodologies for land monitoring and evaluation, the production of information devices (data sets, indices, functions and models, software, thematic maps) to detect in reliable time the evolution and the entity of the desertification processes in the Mediterranean drylands, and a consistent transfer of acquired knowledge and technology to the countries most affected by desertification, carrying out parallel activities to disseminate the results (workshops, lectures, training courses, papers, etc.)The following action guidelines will be performed :* evaluation of the areas, selection of the sample sites; floristic and vegetation analysis, climatic and soil characterization of the selected areas; detection of ve
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Sound Localization by Neuronal Populations in the Rat Auditory Cortex'.

assistant: **Innovation**

How does the accuracy of sensory representations constrain the ability of the organism to perform perceptual discriminations? In this project, we will address this issue by characterizing the activity of populations of neurons in the rat auditory cortex while they perform a two-alternative forced-choice discrimination task for detecting sound location relative to the midline. We will first establish how location and spectral features of sound are represented by cortical populations under anesthesia, and subsequently during performance of the sound localization task. Due to the design of our discrimination task, analysis of the patterns of co-variability in the recorded sensory responses will allow us to elucidate whether the auditory cortex is primarily concerned with maximizing information about auditory stimuli, or whether it constructs representations which are useful for the animal in the context of its current behavioral goals. We will also investigate whether population activity and behavioral choices are correlated in a trial-by-trial basis. By understanding how the activity of multiple neurons has to be combined in order to best predict behavioral choices we expect to learn about the computations that the auditory cortex is performing in order to classify the location of sounds relative to the midline.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Ways of writing. How physicians know, 1550-1950""'.

assistant: **Objectives**

What is paper technology, how does it shape scientific knowledge, and how is this operation interrelated with other domains of the modern world? Downsizing these questions to the field of medicine and its observational practices is the way to achieve these otherwise intractable goals. The first implies the history of medical observations (in any sense) over the long term. The project will explore and demonstrate how writing represents one of the basic operations of a technology of knowledge. The second aim is targeting a history á la longue durée. Demonstrating how shaping knowledge was based on paper technology over this entire period will contribute to the identification of continuities between the early modern period and modern historical eras. This is the fundamentally historical aim of the investigation. The third aim implies an understanding of the relationship between the social world and scientific knowledge. Even the long perspective will show that producing and shaping of knowledge is always intertwined with practices of other social domains – for example, military, judicial, and administrative.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'MAssive intracellular REcording for Pharmacology' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Due to the vital role of the heart, cardiac safety assessment has become one of the major gatekeepers in all stages of the drug development process, increasing costs and resources required for new drugs. Despite the recent advancements of the Comprehensive In vitro ProArrhythmia (CiPA) initiative, there are still important obstacles related to chronic cardiotoxicities and to unreliable cell models. Thus, there is a strong need for new solutions that can improve the efficacy of drug development processes.The MAREP project aims at tackling this problem by demonstrating a novel automated system for the comprehensive pharmacologic investigation of drug effects on in-vitro cardiac cell cultures. The novel approach combines laser excitation of novel metamaterials with high density multielectrode arrays (HD-MEA), providing high quality and high throughput recording of cardiac cells activity and offering an unprecedented and affordable method for the global study of drug effects on the heart. The outcome of the project is the prototype of a system that combines electrical recording of action potentials of thousands of cardiac cells with laser-based cell poration and intracellular recording. In essence, cardiac cells can be investigated in physiological conditions while drugs are administered and their effects studied in details on a large and reliable biological sample. The MAREP technology will boost the development of new drugs through the establishment of a novel, affordable, cost-effective and automated experimental procedure. This project intends to exploit a research innovation born, though not exploited, in the parent ERC project Neuro-plasmonics.This innovation may bring the laser-based bio-nanotechnologies developed in Neuro-plasmonics closer to commercializationby int
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'From Silk to Sealant: The Production of an Enhanced Biomedical Silk Glue Biopolymer from Genetically Engineered Silkworms' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Advancements in post-surgical healing are a major topic in biomedical science and require innovations in materials science. In many medical procedures, current medical glues are more efficient than traditional sutures but they still lack sufficient wet-tolerant adhesive strength. Biopolymers are naturally derived and biocompatible, and present enormous potential for applications such as tissue glue. To address the adhesive challenge, we propose GEMSilk, an innovative and interdisciplinary framework integrating analytical techniques of material science with genetically engineered silk glue. Our key objective is to develop a caddisfly-derived and inherently wet-tolerant aquatic silk glue recombinant protein expression system in the domestic silkworm (Bombyx mori). Utilising CRISPR/Cas9, caddisfly aquatic silk glue DNA motifs will be inserted into the silkworm's silk gene, the resulting stable mutant lines will produce commercial quantities of wet-tolerant silk glue.  By training through research and a secondment at the lab of supervisor Seib’s collaborator, I will gain essential, state-of-the-art skills in novel silk biopolymer design and silk analysis. Moreover, the silk glue product will undergo intellectual property evaluations with Seib, further augmenting my professional skill set with this essential process and the potentials beyond GEMSilk will also be assessed.During GEMSilk, I will gain substantial and rigorous training in silk analysis and essential assays for silks based healthcare. I will be located at Fraunhofer-IME's new world-class multi-disciplinary applied insect biotechnology research institute.  Over the past months, Seib and I have honed GEMSilk. Combining Seib’s profound experience in silk analysis for healthcare with my skills in silkworm genetic eng
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Development of New Drugs for the Treatment of Malaria' (ANTIMAL).

assistant: **Concept**

Leading groups of malaria researchers will integrate their expertise in malaria biology and drug development to exploit new scientific and political opportunities to secure the development of a portfolio of viable novel AntiMalarial drugs. New chemical entities will be commercially attractive to industrial partners and through the generation of PPPs, will result in affordable new AntiMalarial drugs. The scientific programme comprises complementary clusters of basic and applied scientific investigation, building on the technology platforms generated by the BioMalPar NoE providing candidate molecules for evaluation by EDCTP.The IP will focus on: quinolines, peroxides, lipid targets, other targets and post candidate development. The project brings together European research of international reputation in the field of malaria biology and chemotherapy and their collaborators in malaria-endemic areas. Through AntiMal's programme of jointly executed research, 27 European research groups will support the network's goals to generate viable lead drug molecules in collaboration with 6 industrial partners (5 SMEs) and 4 partners from endemic countries (2 SMEs).These activities in strengthening existing European excellence will increase institutional integration and create a durable structure of basic and applied malaria research in Europe with a focus on drugs, and will establish critical mass at the European level and integrate malaria specialists into a virtual drug discovery and development" structure with one focused scientific objective, the delivery of a new drug/s for malaria. We now propose to extend this consortium to iclude a further three African-based partners with exciting drug discovery/development initiatives. The first of these focuses on antifolate based antimalari
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The Evolution of PRDM9 Binding and Genomic Localization of Meiotic Recombination Events' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Meiotic recombination is an essential process for sexually reproducing organisms. The appropriate genomic distribution of recombination events is necessary for the accurate transmission of genetic information from one generation to the next. Extensive research has demonstrated that a major determinant of recombination sites in mice and humans is the DNA-binding protein PRDM9. An intriguing feature of PRDM9 is the exceptionally rapid evolution of its DNA-binding domain, which causes enormous variability in the locations of recombination events, even within a single species. To date, our understanding of PRDM9’s genome-wide distribution is based largely on its predicted DNA-binding specificity, however, the presence of a predicted consensus motif alone is not a strong predictor of recombination locations. Here, I will test the hypothesis that additional factors act in concert with the rapidly evolving PRDM9 protein to specify sites of meiotic recombination events. I will directly map and compare the genome-wide distribution of PRDM9 in different mouse strains to understand the evolution and principles of its binding. I will also pioneer a single-cell based approach that can distinguish between different classes of recombination events to build a high-resolution genome-wide recombination map to further dissect the role of PRDM9, and to identify additional factors, that shape the recombination landscape.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Atmospheric dynamics InfraStructure in Europe' (ARISE) targeting Seventh Framework.

assistant: **Abstract**

ARISE proposes to design a new infrastructure that integrates different station networks in order to provide a new “3D” image of the atmosphere from the ground to the mesosphere with unprecedented spatio-temporal resolution. Three existing networks are involved: 1) the International infrasound network developed for the verification of the Comprehensive nuclear Test Ban Treaty (CTBT), 2) the Network for the Detection of Atmospheric Composition Changes (NDACC) which uses Lidar to measure stratospheric dynamics, 3) the Network for the Detection of Mesopause Changes (NDMC), dedicated to airglow layer measurements in the mesosphere. In addition the network will incorporate complementary infrasound station and satellite data.The infrastructure extends across Europe and outlying regions, including polar and equatorial regions. The network will play a particularly important role in improving atmospheric measurement in the stratosphere. A great deal of recent work has shown that stratospheric variability, primarily caused by large, planetary-scale waves, is important for prediction of tropospheric weather and climate. Additionaly, the network will provide important new measurements of atmospheric gravity waves. Parameterization of gravity waves is needed for accurate simulation of mean climate and variability, but parameters are uncertain due to lack of long-term high-resolution observations.The expected benefits of ARISE are two-fold. First, the measurements will allow a better description of the atmosphere state, leading to an improved accuracy in short and medium range weather forecasts. Second, the measurements will be used to improve the simulation of middle atmosphere climate and its tropospheric impact. In the long term, data will be used for monitoring changes in the occ