RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Advanced propulsion integration aerodynamics and noise' (APIAN) targeting Fourth Framework.

assistant: **Abstract**

Objectives and content:The need to cope with rapidly evolving requirements for economically viable and environmentally acceptable propulsion systems has forced air framers to explore revolutionary systems such as ultra-high by-pass ratio engines especially open rotors. The development (and exploitation) of these novel power plants requires technology to integrate then with the airframe to produce efficient performance and reduced noise for operational configurations. The ultimate goal is a competitive new generation of commuter aircraft with the same operational capacity and comfort as regional jets yet with reduce demission and noise. It is first proposed to investigate in wind tunnels advanced propeller driven aircraft equipped with high-speed propellers (Mach 0.7-0.8). The test rig will primarily consist of an advanced powered wind tunnel model developed in IMT3GEMINI II" programme. This includes an internal six components balance, a set of two air driven high-power turbines (290 SHP Engine Simulators), a set of typical high-speed propellers (Mach 0.78) with rotating balances and instrumentation such as dynamic pressure sensors or microphones.Wings, nacelles and propellers are original design from GEMINI and SNAAP CEC funded research programmes. The powered model will be tested in ONERA S1 transonic wind tunnel and in DNW low speed tunnel to investigate aerodynamics and acoustics of "propeller-to-airframe interactions". The same propellers will be tested on an isolated rig in the same conditions to identify the effect of the airframe. In addition, this isolated rig will be adapted to NLR-HST for transonic regime (up to 2 bars generative pressure) to identify Reynolds effects on the propellers (scale effect). Forces, moments, pressures, radiated noise will be measured
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Defining the intrinsic transcriptional programs and the microenvironmental signals tailoring lung Interstitial Macrophage IDentity' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The mechanisms underlying lung homeostasis are of fundamental biological importance and have critical implications for the prevention of immune-mediated diseases such as asthma. We have demonstrated that lung Interstitial Macrophages (IM) exhibit a tolerogenic profile and are able to prevent and limit the development of aberrant immune responses against allergens, thus underscoring their role as crucial regulators of lung homeostasis. In addition, we have shown that IM could expand from monocyte precursors upon host exposure to bacterial unmethylated CpG-DNA, resulting in robust protection against allergic asthma. To date, however, IM have only been characterized as a bulk population in functional studies, and little is known about the tissue-instructive signals, specific transcription factors and differentiation programs which contribute to determining their identity (ID) and function, as proposed by the macrophage niche model. We have developed an innovative transgenic tool to selectively target IM which, in combination with high dimensional single cell technologies, will allow us to (1) define the precise ID of IM, i.e. their spatial organization, heterogeneity, molecular signature and the specific TF governing their differentiation and function; (2) investigate how IM ID is imprinted by the local niche to sustain lung homeostasis. Specifically, we aim to identify the epithelial cell-derived chemo-attractive signals controlling IM precursor recruitment and to elucidate the contribution of the lung cholinergic nervous system to IM ID and lung homeostasis. This research will increase our understanding of the basic mechanisms underlying the fine-tuning of tolerogenic IM and will thus provide robust foundations for novel IM-targeted approaches promoting health and preven
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Advanced Electronic Materials and Devices through  Novel Processing Paradigms' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

I propose a structured multidisciplinary research programme that seeks to combine advanced materials, such as metal oxides and organics, with novel fabrication methods to develop devices for application in: (1) large area electronics, (2) integrated nanoelectronics and (3) sensors. At the heart of this programme lies the development of novel oxide semiconductors. These will be synthesised from solution using precursors. Chemical doping via physical blending will be explored for the tuning of the electronic properties of these compounds. This simple approach will enable the rapid development of a library of materials far beyond those accessible by traditional methods. Oxides will then be combined with inorganic/organic dielectrics to demonstrate low power transistors. Ultimate target for application area (1) is the development of transistors with hole/electron mobilities exceeding 20/200 cm^2/Vs respectively. For application area (2) I will combine the precursor formulations with advanced scanning thermochemical nanolithography. A heated atomic force microscope tip will be used for the local chemical conversion of the precursor to oxide with sub-50 nm resolution. This will enable patterning of nanostructures with desirable shape and size. Sequential patterning of semi/conductive layers combined with SAM dielectrics would enable fabrication of nano-sized devices and circuits. For application area (3), research effort will focus on novel hybrid phototransistors. Use of different light absorbing organic dyes functionalised onto the oxide channel will be explored as a mean for developing high sensitivity phototransistors and full colour sensing arrays. Organic dyes will also be combined with nano-sized transistors to demonstrate integrated nano-scale optoelectronics. The uni
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'The chemical warfare between sponge and coral species informing reef restoration in Pacific Island communities in Papau New Guinea'.

assistant: **Objectives**

Human activity is predicted to result in a 1.5-4 ºC global warming of air temperature by 2100. The globally averaged ocean surface temperature data shows a mean warming trend of 0.062 ºC/decade since 1900. Since 2010 this has increased to 0.280 ºC/decade. The loss of coral species is decreasing the competitive sponge species chemically fighting for space. Given the imminent threat that global warming has on the future of coral reefs, there is a strong need for robust scientific measures of reef health and future sustainability to improve the survival potential of corals and better inform reef restoration projects, ensuring healthy, diverse, and resilient coral reefs. CIRCLE (ChemIcal waRfare in CoraL rEefs) aims to investigate the influence of climate change on the chemical warfare that occurs in coral reef ecosystems between sponge and coral species, to inform conservation efforts to protect reef ecosystems. We hypothesize that the increasing ocean temperatures are influencing the diversity and distribution of sponge and coral species, where a trade-off is being made between survival and growth. This research will develop critical information for understanding the chemistry and genetic variations required for reef ecosystem growth and (re)-building in response to climate change. It will improve our understanding of future economic and social impacts of global warming on Pacific Island reef ecosystems. CIRCLE will advance the current state of the art application of multi omics techniques to explore the interspecies chemical ecology between sponge and coral species. Through the combined use of omic techniques and chemical natural product experiments we will identify biochemical markers of coral and sponge health. The knowledge gained in this project will empower local Pa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'A Collective Awareness Platform for Promoting Dark Skies in Europe' to be submitted under Horizon 2020.

assistant: **Abstract**

WHY: 2015 has been named by the United Nations as the International Year of Light (light2015.org). Light has had many obvious benefits for human mankind, but it also poses some relevant threats: the everyday-increasing excess of light thrown by humans to the sky seriously threatens to remove forever one of humanity’s natural wonders, the view of our universe. More importantly, it has also an adverse impact on our environment and economy (energy wasted to the sky costs 2 billion US$ per year in the USA and 6,3 billion € per year in Europe) and on the health of hundreds of species, including pathologies in human beings (e.g., stress, insomnia). Many professional and amateur scientists are already fighting against light pollution. However, it is necessary to increase social awareness about the importance of preserving the darkness of our cities and environment.WHAT: STARS4ALL will create an Light Pollution Initiative (LPI) incubation platform that will allow generating (and maintaining) customizable on-demand domain-focused LPIs (e.g., a light pollution working group in Brussels). The platform will be self-sustainable: it will integrate a crowdfunding tool to obtain funding for the LPIs; it will consider incentives that motivate citizens to participate in LPIs, as well as policies to handle those incentives; and it will provide innovations in data acquisition from sensors deployed by citizens and in games with a purpose.HOW: STARS4ALL will initially deploy 10 LPIs, which will be available by the end of the 1st semester of project execution, and will be operating and creating collective awareness during the rest of the project. At that moment we pave the way the creation of other LPIs by citizens, specially in other disciplines such as Energy Saving, Biodiversity, and Human
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Topological Insulator Laser' to be submitted under Horizon 2020.

assistant: **Abstract**

Triggered by condensed matter, a new frontier recently emerged: Photonic Topological Insulators (PTIs). These are photonic structures where the transport of light is topologically protected: light propagates in a unidirectional manner without reflection, even in the presence of corners, defects, or disorder. The first step toward PTIs was the electromagnetic analogue of the quantum Hall effect, employing magnetic fields in gyrooptic media. Bringing the concepts of topological insulators into photonics required fundamentally different effects, eluding researchers until in 2013 we demonstrated the first PTI. That, along with experiments in silicon photonics and pioneering theory work, launched the field of Topological Photonics.   This proposal aims to explore the possibility of the “next big thing”, a fundamentally new concept, never suggested before in any context, with high potential impact on fundamentals and on lasers technology: we will explore the idea of the Topological Insulator Laser.  Topological Insulator Lasers are lasers where the lasing mode is topologically protected: light propagates around the cavity unaffected by disorder and defects. Based on our preliminary studies, we envision that by lasing in a topological mode, the interplay between the topology and gain will lead to a highly efficient laser, robust to defects and disorder, that lases in a single mode even at high gain values. The road to achieve this goes against current knowledge: topological insulators are linear Hermitian closed systems, whereas the topological insulator laser is a non-Hermitian, highly nonlinear, open system. Our study will be theoretical and experimental, starting at the fundamentals of topological transport in systems with gain, and we will take it all the way to experiment
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'New white gold alloys' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Today, there are no other commercial white gold alloys as alternatives to platinum except white gold alloys either with Pd (expensive) or with a little content of Ni (soon completely prohibited). Therefore, the sector of the jewellery always needs of a new white gold alloy for replacing the current not adequate Ni and Pd based gold alloys. The industrial aim of our project is to formulate a new white gold alloy by testing all the bends containing gold and other elements with whitening capacity. The innovation of this project is in the method that will be used. Effectively, the testing process will be the Physical Vapor Deposition (PVD) with three sources of metal in order to screen the color of different alloys by making only coated plate. This technique will permit to make very quick and cheap cartography of the color of the different ternary blends. The first step consists in only coated plates, and the second step in investment casting of the solid alloys.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'A JOINED-UP APPROACH TO THE IDENTIFICATION, ASSESSMENT AND MANAGEMENT OF EMERGING FOOD SAFETY HAZARDS and ASSOCATED RISKS' under Horizon Europe.

assistant: **Concept**

In Europe, each year foodborne hazards, including bacteria, parasites, bacterial toxins and allergens, already cause more than 20 million cases of illness and thousands of deaths. Foodborne chemical risk, often associated with occurrence of toxins, are of growing concern. Food safety management systems established over the past decades in our European food businesses, and European food safety governance need to be adapted to make the food system more robust towards multiple stressor coming dynamically up (so as climatic impacts). FoodSafeR aims to design, develop and test the building blocks of an innovative pro-active and holistic food safety warning and management system with a look on the dynamics of emerging risks at its heart. FoodSafeR embodies integrated approaches to hazard characterisation and risk management in a comprehensive suite of future oriented case studies, tools, methods, strategies, models, guidance and training materials. An open and accessible digital hub designed to form a core of a sustaining information system will be set up as a ‘One-Stop-Shop’ vehicle targeted at risk managers and assessors, food safety authorities and the relevant actors and stakeholders operating in the European food system. To reach the ambitious goal, FoodSafeR has united a world-class consortium of 18 organisations from across 14 European countries integrating science, industry, SMEs and policymakers. FoodSafeR will contribute to prevent food safety incidences occuring from biological and chemical hazards in the European food system as well as relevant socio-economic impacts. By bringing this approach to a success, FoodSafeR contributes to ‘sustainable, healthy and inclusive food systems delivering co-benefits for climate mitigation and adaptation, environmental sustainab
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Multifunctional sustainable adsorbents for water treatment assisted with plasma technologies and for health protection from xenobiotics' in the context of a Horizon Europe call.

assistant: **Objectives**

Contamination of drinking-water is an urgent global health concern, preferentially in rural areas, and is highly related to the poor and vulnerable population.  This challenge requires a single, easy to handle and low-cost solution able to decrease the levels of pathogens, chemical and radiological hazards to tolerable levels in a single and simple pot (from a sorbent on a glass to a more powerful cold plasma technology). Furthermore, climate change, natural disasters and the actual war in Ukraine urges having available fast effective solutions to avoid the spread of waterborne epidemies and being exposed to unsafe levels of heavy metals or hazardous organic pollutants. The complexity of such contamination  including organic/inorganic species, cationic/anionic species, different size and shape, etc., requires a multicomponent system and/or device, in the form of a tablet or monolith, able to tackle specifically each of these hazards at once. In addition, this multicomponent system, besides tacking the problem in water, can be prepared and/or modified to be biocompatible so that it can also be used as a dietary complement to mitigate/remove all these hazards in human body (as enterosorbent). Based on these premises, the main goal of the CLEANWATER project is the design and development of multicomponent sorbents prepared by the combination of safe materials (e.g., activated carbons, bone-chars, pectins, among others) able to eliminate these contaminants in drinking water in a single pot or in combination with cold plasma for complete destruction. Furthermore, this sorbent will be modified accordingly to be applied in human body as a dietary complement to remove these species once assimilated in the body.


**Keywords:** Porous sorbents, water treatment, xenobiotics, enter
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Engineering Cytokines for Super-Affinity Binding to Matrix in Regenerative Medicine'.

assistant: **Concept**

In physiological situations, the extracellular matrix (ECM) sequesters cytokines, localizes them, and modulates their signaling. Thus, physiological signaling from cytokines occurs primarily when the cytokines are interacting with the ECM. In therapeutic use of cytokines, however, this interaction and balance have not been respected; rather the growth factors are merely injected or applied as soluble molecules, perhaps in controlled release forms. This has led to modest efficacy and substantial concerns on safety. Here, we will develop a protein engineering design for second-generation cytokines to lead to their super-affinity binding to ECM molecules in the targeted tissues; this would allow application to a tissue site to yield a tight association with ECM molecules there, turning the tissue itself into a reservoir for cytokine sequestration and presentation. To accomplish this, we have undertaken preliminary work screening a library of cytokines for extraordinarily high affinity binding to a library of ECM molecules. We have thereby identified a small peptide domain within placental growth factor-2 (PlGF-2), namely PlGF-2123-144, that displays super-affinity for a number of ECM proteins. Also in preliminary work, we have demonstrated that recombinant fusion of this domain to low-affinity binding cytokines, namely VEGF-A, PDGF-BB and BMP-2, confers super-affinity binding to ECM molecules and accentuates their functionality in vivo in regenerative medicine models. In the proposed project, based on this preliminary data, we will push forward this protein engineering design, pursuing super-affinity variants of VEGF-A and PDGF-BB in chronic wounds, TGF-beta3 and CXCL11 in skin scar reduction, FGF-18 in osteoarthritic cartilage repair and CXCL12 in stem cell recruitment to