RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The N-IF mouse – a new and unique fibrosis model for preclinical efficacy studies' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

InfiCure Bio is a Swedish Life Science company that was founded in 2015 with the primary objective of developing and commercializing a proprietary model for preclinical efficacy testing of anti-inflammatory and anti-fibrotic drugs. Our key product, the N-IF mouse, is a unique animal model that spontaneously develops fibrosis which is preceded by chronic inflammation and exhibits the same course of fibrotic disease progression as in humans, a unique feature that has been an ultimate need demanded by the pharmaceutical industry for many years. There are no efficient therapies aimed against fibrotic diseases despite the high prevalence among the world population and the huge impact on human health. To date, drug development has been hampered due to the lack of good and reliable preclinical models that better resemble human fibrotic disease conditions. The N-IF mouse eliminates the problems of currently available animal models that are time-consuming, labour-intensive to induce fibrosis and have a low reproducibility. Its unique features will allow to shorten test protocols by 4-8 weeks, increase robustness of tests due to its 100% reproducibility and minimize the number of experimental animals needed. Reductions in experiment time and in mice numbers directly translate into a 25 - 50% decrease in the overall costs of preclinical testing of anti-fibrotic drugs.We have already technically validated the N-IF mouse as a model for liver fibrosis and have acquired two clients. The objective of the Phase 1 project is to conduct a feasibility study and prepare for further validation studies of the mouse model in order to establish the pathology of NASH, renal and pulmonary fibrosis that will be conducted as part of Phase 2, enlarging our pipeline models for fibrotic diseases and o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'European Union Contest for Young Scientists (EUCYS) 2024' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

This proposal concerns the organization of the 35th European Union Contest for Young Scientists (EUCYS), which will be held in Katowice, Poland, in September 2024.The European Union (EU) Contest for Young Scientists (EUCYS) is the most important student science fair in the EU, showcasing the best of student scientific achievement in the EU and beyond. Each year, the event brings together promising, talented students & bright young minds (14-20 years old) from all over Europe and beyond, to present their projects to a panel of international judges.The competition helps promote science and research, and draws attention to young talents in European and global countries. During the competition, young scientists have the opportunity to meet other participants with similar interests, confront their project with other young scientists' activities, and talk with the judges - the most prominent scientists in Europe. The EUCYS competition works to attract young people to careers in science and technology.


**Keywords:** European Union Contest for Young Scientists 2024 EUCYS, Katowice Poland, Youth, Science, STEAM, youth development
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'High-Performance Large Area Organic Perovskite devices for lighting, energy and Pervasive Communications' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

PeroCUBE will advance the organometal halide perovskite technology, a class of low-cost but high-quality materials which exhibit strong potential to dominate the OLAE market with the focus given on flexible, lightweight electronic devices. While these materials are extensively studied for the developments of the next generation of solar cells, PeroCUBE will focus on scalable manufacturing processes (roll-to-roll printing) and future market entry of new products. PeroCUBE develops large area lighting panels (PeLEDs) which offer distributed lighting in line with the human-centric lighting concept, such devices surpass OLEDs in terms of performance over cost ratio and will assist the European industry to maintain industrial leadership in lighting. Moreover, PeroCUBE further advances scalable manufacturing of perovskite-based photovoltaic panels (PePVs). Developments on both PeLEDs and PePVs will be also demonstrated in a new generation of Visual Light Communication (VLC) /LiFi technologies. The PeroCUBE developments will be demonstrated in coupled energy-harvesting/light-emitting devices and wearables (bendable wristbands).


**Keywords:** organic electronics, perovskites, roll-to-roll printing, high-throughput manufacturing, LED,  photovoltaics, solar cells, visual light communication, LiFi, lighting
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'A therapeutic vaccine candidate for lung cancer based on an exclusive cell line of Plasmacytoid Dendritic Cells (PDC*line)' (PDClungSME1).

assistant: **Innovation**

Since 2014, the revolution of immuno-oncology gives unprecedented hope for cure to cancer patients thanks to immunotherapies such as anti-PD(L)-1. However around 80% patients still don’t respond to anti-PD(L)-1. Several barriers are still to be overcome to sustain the path of a novel paradigm responding both unmet therapeutic needs and health economy sustainability; cancer being estimated as a leading cause of deaths in Europe (350’000 deaths in 2012– Globocan) corresponding to an economical burden of €126BN in total costsPDC*line Pharma develops a ground-breaking therapeutic vaccine platform using an exclusive cell line of Plasmacytoid Dendritic Cells (PDC*line); potentially doubling the response rate to anti-PD(L)-1 without additional toxicity, eliminating complex and costly process usually required by cell therapies.Our innovation project is aiming to establish the clinical proof of concept that PDC*lung, our leading candidate for lung cancer can induce strong anti-tumour immunity in patients. Lung cancer is of high priority for Europe since 1.9 million people are affected worldwide of which 340 000 in Europe (Globocan, 2012). It also represents an attractive market segment opportunity for PDC*line Pharma with an expected market growth of 4% per year: $6.1BN in 2013 to $8.6BN in 2023 worldwide (IMS, 2015).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Effect of 4500bar injection pressure and super-critical phase change of surrogate and real-world fuels enriched with additives and powering Diesel engines on soot emissions reduction' in the context of a Horizon 2020 call.

assistant: **Objectives**

Reduction of soot emissions from Diesel engines will be explored by utilising simultaneously (a) injection pressure between 2000-4500bar, (b) engine operation at supercritical conditions relative to the injected fuel’s critical point and (c) additives that improve atomisation and reduce pollutant formation. The detailed processes of nozzle flow cavitation/boiling, atomisation, phase-change and mixing, combustion and soot emissions under such conditions will be explored both experimentally and computationally. Experimental techniques include fuel property measurements, optical/laser diagnostics, high speed imaging, micro CT and high energy X-rays. Tests will be performed in CVC, optical engines, single-cylinder and production engine test beds. Identification of nozzle’s internal geometry and testing of clean and aged injectors with internal deposits build-up is central to the programme. Simulation tools to be developed include molecular-structure-based equation of state for the properties of surrogate, ‘summer’ Diesel and low quality Diesel fuels enriched with additives at elevated pressures/temperatures, DNS for bubble dynamics, cavitation and fuel atomisation, and soot oxidation in LES/RANS models coupling the in-nozzle flow with the macroscopic fuel spray development, mixing and pollutant formation in engines. The validated simulation models will be used as design tools to industrial development of fuels, fuel injection systems and Diesel engines. The 15 EU-funded ESRs plus 1 ESR funded independently by industry, will be recruited/seconded by universities, research centres and multinational engine, fuel injection system, fuel and fuel additives manufacturers from the EU, US, China, Japan and S.Korea. The new tests and the developed simulation tools, currently missing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Integrated Services for Infectious Disease Outbreak Research' (ISIDORe) targeting Horizon Europe.

assistant: **Abstract**

The ISIDORe consortium, made of the capacities of European ESFRI infrastructures and coordinated networks, proposes to assemble the largest and most diverse research and service providing instrument to study infectious diseases in Europe, from structural biology to clinical trials. Giving scientists access to the whole extent of our state of the art facilities, cutting edge services, advanced equipment and expertise, in an integrated way and with a common goal, will enable or accelerate the generation of new knowledge and intervention tools to ultimately help control SARS CoV 2 in particular, and epidemic prone pathogens in general, while avoiding fragmentation and duplication among European initiatives. Such a global and interdisciplinary approach is meant to allow the implementation of user projects that are larger, more ambitious and more impactful than the EU supported transnational activities that the consortium is used to run. Our proposition is ambitious but achievable in a timely fashion due to the relevance and previous experience of the partners that we have gathered and that have complementary fields of expertise, which addresses the need for an interdisciplinary effort. Leveraging all these existing strengths to develop synergies will create an additional value and enhance Europe capacity for controlling emerging or re emerging and epidemic infectious diseases, starting with the COVID 19 pandemic. Such a global and coordinated approach is consistent with the recommendations of the One Health concept and necessary to make significant contributions to solving complex societal problems like epidemics and pandemics.


**Keywords:** responsiveness, preparedness, epidemic prone pathogens
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Gallium Arsenide Second-Window Quantum Dot Lasers' to be submitted under Fifth Framework.

assistant: **Abstract**

We propose to demonstrate in-plane and vertical cavity diode lasers operating at 1300nm using (Ga, In) As quantum dot emitters. These devices based on GaAs substrates are expected to exhibit superior characteristics compared to the classical GaInAsP on InP based devices, with the advantage of lower cost, compatibility with the well established GaAs processing technology, improved reliability and decreased temperature sensitivity. The project will demonstrate 1300nm optical links based on this all GaAs technology and compare the performances with 1300nm GaAs devices.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Chemogenomics and in silico repurposing as an innovative approach for rapid drug discovery in tuberculosis'.

assistant: **Innovation**

Tuberculosis is one of the most worrying Global and Public Health problems in the present day and causes a major economic and social burden, which can significantly drain a society’s resources. In 2015, 10.4 million people fell ill with tuberculosis and 1.8 million died from the disease. In addition, an estimated 480000 people developed multidrug-resistant tuberculosis.  The development of new drugs and new therapeutic regimens effective against drug susceptible and drug resistant tuberculosis is one of the greatest challenges in the way of tuberculosis control. Conventional drug discovery strategies are usually costly and time-consuming and, frequently, with low rates of success. This project aims to develop a new paradigm for tuberculosis drug development, using the drug repurposing strategy (to find new uses for already approved drugs) coupled with an in silico chemogenomics method. The focus will be targeting energy metabolism, particularly the oxidative phosphorylation, a novel target pathway in tuberculosis drug discovery. This research project has the potential to greatly benefit tuberculosis drug discovery by finding new drugs for a largely unexplored pathway and by introducing a new approach that can increase the probability of identifying effective drugs and decrease the bottlenecks of the conventional drug discovery approach, saving both time and money. Since tuberculosis has a high social and economic impact, this project aims not only to contribute to scientific and academic knowledge in this field, but also to increase public awareness on tuberculosis drug resistance and the need for new drugs by using several outreach activities. Finally, searching for new effective drugs that can tackle the problem of drug resistance and reduce the costs of drug treatmen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Software Engineering Metrology', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

Throughout the industry, and the scientific community, measurement is perceived as being pervasive as a fundamental engineering tool. Until recently in software engineering, 'software metrics' have most often been proposed as the quantitative tools of choice, and analysis of these tools was most often carried out them from the perspective referred to as measurement theory". However, in other disciplines, it is the domain of knowledge referred to as "metrology" that is the foundation for the development and use of measurement instruments and measurement processes.In the software engineering literature, numerous practitioners and researchers have proposed hundreds of 'software measures', or 'software metrics'. To help industry assess the quality of these proposed measures, various researchers have proposed various approaches to software measurement validation, none of which has yet been widely used by either designers or users of software measures. To tackle this diversity, this research chair program will review proposed validation frameworks using a key ISO document on measurement, that is, the ISO Vocabulary on Metrology as well as a measurement process model derived from an analysis of the individual validation proposals.The metrology concepts in particular have facilitated a greater understanding of the set of measurement sub-concepts that must be included in each of the steps from the design of a measurement method to the use of the measurement results. This research chair program will build upon previous research results to develop and design a metrology related approach to software measurement."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Novel Magneto-Optical Biosensors for Malaria Diagnosis' to be submitted under Sixth Framework.

assistant: **Abstract**

The objective of this proposal is to develop new, fast and effective instrumentation for the diagnosis of malaria by a non-invasive methodology that permits the precise in-vivo analysis of certain specific blood characteristics. It is prompted by the devastating effects of malaria on health and national economies in the third world, the threat to southern European states following climate change. The malarial parasite is known to modify the magnetic properties of red blood in proportion to the degree of infection through conversion of haemoglobin to haemozoin thus changing the magnetic properties.This proposal will investigate these changed magnetisation states using both the magneto-optical and magneto-thermal interactions of blood as a basis for a potential bio-sensing system for malaria. Currently the most common method of diagnosing malaria is by observation of infected blood using microscopy by trained microscopists. This is time consuming and cannot be accomplished in the field.The project objectives are two prototype instruments:1) A portable instrument based on electronic measurement of the magneto-optic response of a blood sample.2) A completely non-invasive instrument requiring no blood sample and hence avoiding potential cross-infection and HIV issues.This project will attempt to break new ground in the field of medical diagnosis using magneto-optics and photonics to access information from biological samples that can therefore be interrogated electronically and potentially non-invasively. The use of these techniques is not confined to malaria diagnosis, having wider application for longer-term development in providing a means of interrogating the condition of biological samples where diseased states (cancerous tissues, leukaemia, diabetes) can be identified
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Olfactormativity: Exploring the Intervening Performativity of Smell' (OLFAC) under Horizon Europe.

assistant: **Objectives**

Smells intervene in human experience. Used by police or military for crowd control, they are a perfidious weapon. Yet, they also offer a wealth of material for intervening arts, the exploration of which is currently gaining traction against a backdrop of climate change and the rise of sexism and racism. So far, however, research on the intervening potential of smell has remained the province of Military Sciences, with research on intervening arts focusing on the visual and the auditory, neglecting the disruptive power of olfaction. OLFAC bridges this gap by, for the first time, exploring the intervening performativity of smell at the intersection of arts and politics. Assuming that odour can be used both to stigmatize and, at the same time, to help “unlearn” socially trained norms, OLFAC will (1) empirically investigate olfactory actors, techniques and technologies applied across performing arts and governmental contexts and (2) develop an integrative, transculturally aligned, and intersectionally oriented theory of Olfactormativity. Fundamentally, the project explores the following questions: How do olfactory techniques and technologies applied in performing arts relate to those used by police and military? What dangers and potential for change do they pose? In what sense are olfactory actors capable of interrupting, subverting or displacing movements of assembly? To what extent can olfactory art break up historically evolved social structures and change perceptual routines? Does the subversive use of odours lead to radical ruptures and changes in terms of gender, class, and ethnicity? Or does it ultimately lead to strengthening conventional concepts of identity? A highly transdisciplinary endeavour, OLFAC draws together approaches and findings from Art-Related Discipl