RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Setting a New Stage in Portugal: Researchers and the public come together through Arts and Sports'.

assistant: **Concept**

Continuing the SettingTheStage project organized in 2009, scientists will be called again on stage to celebrate the Researchers’ Night 2010 not only through performing arts (incl. theatre) but also through sports. These media will allow scientists to express themselves, their visions and their work. SettingTheStage II brings back together entities from four major cities across Portugal (North, Centre, South) with the aim of creating multiple spaces where scientists and the public can actively engage in the reality of being a scientist. At the core of the project is a series of arts performances to be specifically produced for RN2010, designed to stimulate reflection, discussion and debate on topics related to researchers and their everyday lives: the power and limits of their research, the impact of their research in society. Researchers and arts performers will work together to produce several performances, aimed at different age groups. In the same way, researchers and the public will share and discuss scientific concepts linked to the sports activities that will be organized during the event. Themes for the activities will be, among others, linked to the celebration of the International Year of Biodiversity and the World Day of the Heart, which will be celebrated at the end of September. Artistic performances and sport activities will be complemented with interactive hands-on activities, from small experiments and demos for youngsters, to speed-dating sessions with scientists, science cafe/bar and visits to museums. Awareness will be achieved through a concerted marketing campaign, bringing together the expertise and resources of all partners involved, including the maintenance/updating of the 2009 project design/image, website and blog. SettingTheStage II brings bac
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Quantitative Tomography Using  Coupled Physics of Waves' under Horizon 2020.

assistant: **Concept**

Tomographic images are a valuable tool in various applications of medicine and biomedicine, industry and in security applications. Although efficient tomographic imaging techniques exist, development of new modalities that would overcome the limitations of the existing techniques are required. Overall, there is a need for development of new tomographic techniques that would provide quantitative information of unknown parameters of interest, such as tomographic images on the concentration of molecules. In particular, information on the reliability of the tomographic images is required. The objective of the project is to develop quantitative tomographic imaging technique based on coupled physics of waves. In coupled physics imaging, contrast and resolution originating from different physical phenomena are combined. In the project, light, microwaves and ultrasound, i.e. waves, will be utilised through photoacoustic, thermoacoustic and acousto-optic effects. These techniques will be developed to produce tomographic images with an outstanding quantitative contrast in the sense of statistical information and modelling of uncertainties, combined with superior resolution and imaging depth. Most tomographic imaging techniques are ill-posed problems that need to be approached in the framework of inverse problems. In the project, a Bayesian approach to ill-posed inverse problems, which supports the quantitative nature of the problem, will be taken. In the project, mathematical modelling and computational methods will be developed in close connection with experimental system development. The research is founded on a strong understanding of the underlying physics of coupled physics problems, knowledge on instrumentation on the related fields and experimental tomography, and state-of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Spatial protein quality control and its links to aging, proteotoxicity, and polarity'.

assistant: **Innovation**

Propagation of a species requires periodic cell renewal to avoid clonal senescence. Mylaboratory has described a new mechanism for such cell renewal in yeast, in which damagedprotein aggregates are transported out of the daughter buds along actin cables to preserveyouthfulness. Such spatial protein quality control (SQC) is a Sir2p-dependent process and by establishing the global genetic interaction network of SIR2, we identified thepolarisome as the machinery required for mitotic segregation and translocation of proteinaggregates. In addition, we found that the fusion of smaller aggregates into large inclusionbodies, a process that has been suggested to reduce the toxicity of such aggregates, requiresactin cables and their nucleation at the septin ring. Sir2p controls damage segregation byaffecting deacetylation and the activity of the chaperonin CCT, enhancing actin folding andpolymerization. Considering that CCT has been implicated in mitigatingaggregation/toxicity of polyglutamine proteins, e.g. huntingtin, and that actin cables isaffecting formation, fusion, and resolution of aggregates, we hypothesize that CCTdeacetylation may underlie Sirt1¿s (mammalian orthologues of Sir2p) documented beneficialeffects in several neurodegenerative disorders caused by proteotoxic aggregates. This projectis aimed at approaching this hypothesis and to elucidate, on a genome-wide scale, how thecell tether, sort, fuse, and detoxify aggregates with the help of CCT, actin cables, and thepolarity machinery. This will be accomplished by combining the power of synthetic geneticarray analysis, high-content imaging, genome wide proximity ligand assays, and microfluidics.Using such approaches, the project seeks to decipher the machineries of the spatial qualitycontrol network as a means to id
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Predictive mOdelling Tools to evaluate the Effects of Climate change on food safeTy and spoilage' (PROTECT).

assistant: **Innovation**

Climate change and food safety have become interdependent worldwide research priorities. In order to meet the EU challenge of doubling food production by 2050 (to meet population demands) while dealing with the impact of climate change on food safety, investment in research to address this issue is required. The overarching aim of this Innovative Training Network (ITN) is to provide high-level training in Predictive mOdelling Tools to evaluate the Effects of Climate change on food safeTy (PROTECT) to a new generation of high achieving early stage researchers. PROTECT will provide them with the transferable skills necessary for thriving careers in a burgeoning area that underpins innovative technological development across a range of diverse disciplines. This goal will be achieved by a unique combination of “hands-on” research training, non-academic placements, summer schools and workshops on research-related and transferable skills facilitated by the academic and non-academic composition of the consortium. PROTECT brings together intersectoral and multidisciplinary expertise from 11 European Countries (7 third level educational institutions, 6 industry partners, 1 United Nations agency). The consortium will share technical and training expertise to recruit and train 8 highly skilled ESRs in advanced modelling tools to investigate the impact of climate change on food safety, considering food as unsafe if it is injurious to health (due to pathogenic bacteria or mycotoxins) or unfit for human consumption (due to spoilage bacteria). Moreover, PROTECT will use this new knowledge to create a science based decision support tool and develop policy guidance through a white paper. The consortium will support specialist job creation in an area central to human and environmental he
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Improving EU-risk assessment of toxicants for aquatic communities by considering competition on the population and community level' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

At present prospective risk assessment (RA) of toxicants is based on laboratory single-species tests and field test systems used in regulatory testing (91/414/EEC). Retrospective effects of contaminants are assessed by field monitoring (2000/60/EEC). The EU-SETAC workshop EPIF (France, 2004) identified a gap between the results of prospective and retrospective RA: Prospective RA should be improved by integrating environmental parameter. Competition was identified as such a parameter as it is ubiquitous present in natural populations and communities. Hence, there is an urgent need to incorporate this parameter into future RA. Also recent papers of the applicant and studies of other authors indicate the great importance of competition for forecasting chronic effects of toxicants on the community level. However, it remains the question on how to integrate competition in RA. In the light of this situation the aim of the project INTERACT is to improve the scientific basis of risk assessment concerning the parameter competition. To achieve this, investigations of the role of competition will be conducted on three levels of biological organisation: (i) a one-species system of aquatic invertebrates (ii) a two-species system (iii) and a multi-species mesocosm system with a nearly natural aquatic invertebrate community. The expected major outputs of INTERACT will be: (a) basic ecotoxicological knowledge about the interaction of toxicants and competition. On the basis of this mechanistic understanding additional outputs of the project will be (b) support for the interpretation of the above-mentioned regulatory tests and (c) of field monitoring data from retrospective RA according the EU water framework directive. The applicant has a strong interest to conduct his work at the worki
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Advanced Nuclear Safety Evaluation of Liquid Metal Using Systems' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

The importance of low carbon energy sources in the efforts against rapid climate change makes nuclear energy part of a sustainable energy mix. Although there have been years of experience feedback with water cooled reactors, fundamental improvement, particularly regarding intrinsic safety and reduced nuclear waste generation is possible using advanced nuclear designs.  Heavy metal cooled systems such as the lead fast reactor (LFR) combine the advantages of a fast reactor system that reduces waste with the intrinsic safety related properties such as the high boiling point, chemical inertia and improved heat transfer. ANSELMUS responds to the Horizon-Euratom -2021-NRT-01-02 call ?Safety of advanced and innovative nuclear designs and fuels. Its objective is to contribute significantly to the safety assessment of  heavy-liquid-metal (HLM) systems, in particular ALFRED and MYRRHA as these are included in the roadmap for the development of advanced systems in Europe. It will use the maturity of both designs to create two detailed phenomena identification and ranking tables (PIRT) that identify all verification and validation needs and are used for further safety evaluation. The project will also experimentally validate key safety related sub-systems including the safety rods, failed fuel pin detection and the coolant chemistry control system. We also will improve the validation of numerical models describing the fuel assembly through experiments and simulations and work on reactor safety monitoring and inspection of HLM systems focusing on high temperature vessel inspection. Moreover, ANSELMUS will look into the societal impact of HLM reactors by assessing the integration of LFR in a mixed energy landscape, including economical aspects, and by addressing social and ethical co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Research evidence for primary health care reforms (phcr) to medical emergency services', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

Cuba is working in an INCO Project to evaluate PHCR for Medical Emergency Services. In May 2002, different National and International organizations are promoting in Cuba the First Convention In Public Health, where we have opened apace to dialogue and collaborate in a conference, based in scientific evidence on Health System Research (HSR), to address the challenges of the EC and other regions, for attending medical emergencies and for setting priorities in Health Reform. Through the mobilization of experts from the EC and other countries and younger scientists in the fields of Public Health, Sociology, Economics and others to share the state-of-art of HSR, calling for papers to be presented, conducting the meeting for strengthen networking and choosing new priorities for PHCR, holding an intensive course on HSR methods and techniques and disseminating the information and research results in a CDROM, we hope to reach the objectives.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Epigenetic and metabolic regulation of endothelial heterogeneity' under Horizon 2020.

assistant: **Concept**

Heterogeneity within the endothelium is increasingly recognized in both normal and disease conditions, influencing vascular architecture, structure, and function. The diverse phenotypes that endothelial cells (ECs) adopt suggest substantial plasticity and indicate that heterogeneity is a core property that enables ECs to fulfill their tissue-specific tasks. However, the molecular basis for tissue-specific endothelial differentiation and heterogeneity remains largely unknown. In this project, we will study the impact of environmental context on endothelial specialization and focus on the emerging relationship between metabolism, epigenetics, and cellular differentiation. We hypothesize that organ-specific differences in endothelial metabolic state, through altered epigenetics, promote specialization and thereby contribute to heterogeneity within the vascular system. The proposal rests on the notion that many of the enzymes that erase epigenetic modifications (from DNA and histones) are exquisitely sensitive to changes in metabolism as they utilize cosubstrates that are generated by cellular metabolism. Using a combination of state-of-the-art genetics, high-resolution imaging, metabolomics, and biochemistry, we will study the role of these epigenetic mechanisms for general and organ-specific blood vessel formation (Objective I) and determine their regulation by metabolic and vascular differentiation signals (Objective II). Moreover, we will explore whether metabolic changes during obesity and aging impact the maintenance of endothelial specialization, and assess whether deregulation of metabolic-epigenetic signalling leads to endothelial malfunction and organ failure (Objective III). We trust that the knowledge gained through this project will provide a conceptual framewo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'An innovative Pulsed Laser Deposition process for next generation of Li-ion batteries' (Coldab), addressing dissemination and exploitation.

assistant: **Impact**

Although the global number of EVs has been increasing since 2010, EVs still have only 1.4% of global vehicle market share. This is mostly due to the fact that the development in the battery industry has been rather incremental, without revolutionary breakthrough since 1991’s launch of the first commercial Lithium-Ion batteries (LIB) by Sony. The advancement and maturity of the battery directly influence the industrialization of EVs. Thus, the biggest challenge the EV market is facing today is related to the limitations of batteries. These are mainly related to insufficient performance, in terms of size, energy density and safety (EV batteries are very flammable), and to expensive battery production, as available deposition methods generally fail to meet the requirements necessary to scale up and automate the production and require fixed casting on each battery specification type. Pulsedeon developed Coldab, a film coating process leveraging Ultra-Short Pulsed Laser Deposition (USPLD), that can optimize the production of LIB components on a large scale. Coldab’s unique PLD coating process allows cost-effective manufacturing of a new class of safer, smart tailored, high-performance EV batteries. Pulsedeon favors the competitiveness of European battery producers by offering a cutting-edge manufacturing process, and promotes a ‘clean environment’. In order to increase the EV’s affordability and improve their performance, Coldab brings EV’s battery manufacturing to a new level of scalability guaranteeing cost-effectiveness, at the same time preserving excellent performance by increasing the battery’s energy capacity and safety. During the phase 1 feasibility study, Pulsedeon will establish a sound go-to-market strategy and supply chain, and will draft further development pla
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Researchers Changing Society' (CHANGE), addressing dissemination and exploitation.

assistant: **Impact**

The CHANGE project aims to foster collaboration between the public and researchers in Finland in order to improve our everyday life in a rapidly changing world. This project brings together 9 universities, 1 research institute and two expert organisations for science communication. It spans many facets of research in Finland and covers numerous individual researchers with diverse backgrounds and research topics. We will deliver a message of cutting edge research conducted in Finland and introduce the general public with the large number of researchers and the significant work they perform. We want to break stereotypes the general public may have on researchers. The programme for activities during the night will include content for everyone, from children to seniors. However, the specific aim is to promote research careers especially to high school and university students, and young people in general who are about to make their first real career choice. Our message is that high education is fun and could provide them with a secured future. For the first time, so many Finnish universities and organisations will unite for a widespread European Researchers’ Night and perform simultaneously activities targeted for the general public around the country.


**Keywords:** Research in Finland, Science communication, Centenary of Finland, Change, Multidisciplinary, National, Science, Arts