RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Assessing microphytobenthos structure in intertidal mudflats using visible - infrared remote sensing and pigment analysis by HLPC'.

assistant: **Objectives**

Microphytobenthos, which is composed of photosynthetic unicellular organisms, could be the most important primary producer in coastal ecosystems containing large intertidal mud flats. In fine-sediment tidal areas, it is composed mainly of diatoms found in the upper millimetres of illuminated sediments where they form biofilms. These biofilms can become part of the phytoplankton when suspended by tidal currents and the interaction of wind and waves with the bottom. In fact, they may constitute much of the fo od available to the meio- and macrofauna. However, these ecosystems are not easily accessible because of the presence of fine sediments that form coastal mudflat. This difficulty limits the number of measurements essential for understanding the spatial st ructure of the populations concerned (structure in this sense signifies the spatial distribution of the biomass, but also the taxonomic composition of the populations). Remote sensing enables this difficulty to be overcome. Microphytobenthic populations c an be mapped from images calibrated by radiometric measurements in the field in association with pigment analyses (characterisation and quantification) of the sediment surface by high-performance liquid chromatography (HPLC). The main objective of this pro ject is to determine the spatial distribution, biomass and composition of microphytobenthos assemblages in two macrotidal ecosystems of the European Atlantic coast: Bourgneuf Bay (south of the Loire estuary, France) and the Tagus estuary (Portugal). These data will be used to assess the importance of these primary producers for the carrying capacity of the ecosystems. This objective will require thorough knowledge of pigment analyses in marine sediments by HPLC, expertise possessed by the Oceanographic Inst itute
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Membrane-based nano-mechanobiology: Role of mechanical forces in remodelling the spatiotemporal nanoarchitecture of the plasma membrane' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Through evolution, cells have developed the exquisite ability to sense, transduce and integrate mechanical and biochemical signals (i.e. mechanobiology) to generate appropriate responses. These key events are rooted at the molecular and nanoscale levels, a size regime difficult to access, hindering our progress towards mechanistic understanding of mechanobiology. Recent evidence from my Lab (and others) shows that the lateral nanoscale organisation of mechanosensitive membrane receptors and signalling molecules is crucial for cell function. Yet, current models of mechanosensing are based on force-induced molecular conformations, completely overlooking the chief role of mechanical forces on the nanoscale spatiotemporal organisation of the plasma membrane.The GOAL of NANO-MEMEC is to provide mechanistic understanding on the role of mechanical stimuli in the spatiotemporal nanoarchitecture of adhesion signalling platforms at the cell membrane. To overcome the technical challenges of probing these processes at the relevant spatiotemporal scales, I will exploit cuttingedge biophysical tools exclusively developed in my Lab that combine super-resolution optical nanoscopy and single molecule dynamics in conjunction with simultaneous mechanical stimulation of living cells. Using this integrated approach, I will: First: dissect mechanical and biochemical coupling of membrane mechanosensing at the nanoscale. Second: visualise the coordinated recruitment of integrin-associated signalling proteins in response to force, i.e., mechanotransduction. Third: test how force-induced spatiotemporal membrane remodelling influences the migratory capacity of immune cells, i.e., mechanoresponse. NANO-MEMEC conveys a new fundamental concept to the field of mechanobiology: the roles of mechanical
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Upscaling reactive transport in unsaturated media: from the pore to the vadose zone' (Uplift), addressing dissemination and exploitation.

assistant: **Impact**

The vadose zone is the unsaturated region connecting the land surface to groundwater, acting as a filter for nutrients and contaminants and controlling their access to aquifers. Reactive transport in unsaturated porous media is of central importance to our understanding of nutrient cycles and applications such as soil and groundwater remediation. Geological media are heterogeneous across scales, and desaturation leads to complex patterns of air and water and preferential flow channels, enhancing structural heterogeneity. Resolving all scales is unfeasible, severely limiting the capacity of current models to predict field-scale reactivity and the spatial distribution of dissolved reactant plumes in the vadose zone. Uplift proposes a shift in perspective from empirical parameterization to the development of upscaled models rooted in a firm understanding of pore-scale dynamics. The underlying hypothesis is that a framework capable of quantifying subscale mixing limitations, combined with a coarse field-scale description of flow, can significantly improve current models. This requires a better understanding of pore-scale dynamics under unsaturated conditions, along with a theoretical framework capable of capturing their impact at larger scales. Uplift aims to address these challenges by connecting stochastic models of transport to statistical pore-scale features, and combining them with a novel population dynamics framework for reactive transport connecting effective reaction rates to delays due to transport limitations. To support the theoretical developments and complement available data, resolved simulation tools developed in the project will be employed to assess the role of degree of saturation, pore-scale structure, and transient forcings on phase distribution statist
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Early Modern State Development in Yemen' (2014-2020).

assistant: **Concept**

How do early modern states organize effective rule in difficult conditions? EMStaD YEMEN focuses on a country that due to its geographical, religious and social complexities is now considered a failed state – Yemen. The project analyzes how this state achieved stability in the early modern period in the conditions that were similar to those hampering its contemporary development. Scholarship on early modern Islamic history usually focuses on the great Islamic empires, like the Ottoman Empire, while the regions conquered by them, notably the Arab lands, are often viewed through the lens of ‘decline’. EMStaD YEMEN challenges this approach by bringing attention to Yemen as a unique case of an Arab state gaining independence from the Ottoman Empire. Combining understudied Ottoman Turkish and Classical Arabic manuscript sources with the method of comparative study of empires, the project focuses on the influence of the period of Ottoman rule (1535-1638) on the development of the state in Yemen. The project first identifies the innovations in administrative practices, document production, and public ceremonies that were introduced by the Ottoman administration. It then traces the afterlives of these developments during the post-Ottoman period of Yemen’s history. The goal of the project is twofold: (1) to explain how, despite the divisions that supposedly turned modern Yemen into a failed state, a stable political system existed in the region during in the early modern period; and (2) to bring Yemen into the broader context of early modern state transformations in Eurasia. The results of the project will be disseminated through publications for specialists and through an exhibition and blog posts for the general public. The longstanding tradition of Middle Eastern studies, reg
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Cryogenic Rare-event Observatory with Surface Sensitivity' under Horizon 2020.

assistant: **Concept**

CROSS will set the grounds for large-scale experiments searching for neutrinoless double beta decay with zero background at an exposure scale of ~1 tonne x year and with very high energy resolution – about 1.5‰ – in the region of interest. These features will enable searching for lepton number violation with unprecedented sensitivity, penetrating in prospect the direct-ordering region of the neutrino masses. CROSS will be based on arrays of TeO2 and Li2MoO4 bolometers enriched in the isotopes of interest 130Te and 100Mo, respectively. There are strong arguments in favor of these choices, such as the high double beta transition energy of these candidates, the easy crystallization processes of TeO2 and Li2MoO4, and the superior bolometric performance of these compounds in terms of energy resolution and intrinsic purity. The key idea in CROSS is to reject surface events (a dominant background source) by pulse-shape discrimination, obtained by exploiting solid-state-physics phenomena in superconductors. The surfaces of the crystals will be coated by an ultrapure superconductive aluminium film, which will act as a pulse-shape modifier by delaying the pulse development in case of shallow energy depositions, exploiting the long quasi-particle life-time in aluminium. This method will allow getting rid of the light detectors used up to now to discriminate surface alpha particles, simplifying a lot the bolometric structure and achieving the additional advantage to reject also beta surface events, which unfortunately persist as an ultimate background source if only alpha particles are tagged. The intrinsic modularity and the simplicity of the read-out will make CROSS easily expandable. The CROSS program is focused on an intermediate experiment with 90 crystals, installed undergrou
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Safe and effective pesticidal microorganisms through customize environmentalpersistance' (1994-1998).

assistant: **Concept**

The scientific and technical objectives of this research concern the application of novel technologies to microorganisms for a cost effective environmentally neutral alternative to chemical pesticides. Research is required into parameters and methods required to ensure customized environmental persistence of the organisms. Problem of dessication are addressed.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Wavelength tunable Advanced Single Photon Sources' under Seventh Framework.

assistant: **Concept**

Quantum communication and computation are emerging fields with the potential to launch new technologies to control, propagate and process information. Amongst candidate systems for transporting quantum information, photons are the most promising as they can both maintain coherence over long distances, and interact strongly with electrons to generate nonlinear effects and allow transfer of information between subsystems. As a result, use of photons as 'qubits' has led to ground-breaking demonstrations of quantum entanglement, quantum teleportation and quantum cryptography. However in many of the devices being developed for use in quantum photonics, particularly solid-state devices such as single photon sources, decoherence suffered by the participating electrons is a key limiting factor, reducing the interaction strength and randomizing the quantum state of the photons. In order to minimise the effect of electron decoherence, such devices must generally be operated under cryogenic conditions; even then, in many cases, other noise mechanisms are revealed which limit device functionality. As a result of these practical obstacles and performance limitations, single photon sources have yet to find widespread use and photonic quantum information is largely confined to laboratory demonstrators.The WASPS project seeks to overcome these major bottlenecks in the technology by taking a revolutionary approach. Namely, we plan to exploit the potential of cavity quantum electrodynamics in the bad emitter limit where decoherence is mostly due to the artificial atom. In this limit, preliminary results show that cavity filtering properties and the Purcell effect can be used to engineer the electron-photon interaction, thereby turning electron decoherence into an advantage rather than an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Role of myeloid cells, their mediators and their antibody receptors in allergic shock (anaphylaxis) using humanized mouse models and clinical samples' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Anaphylaxis is a hyperacute allergic reaction of increasing incidence that can be of fatal consequence and that has no specific treatment. Anaphylaxis is thought to rely on mechanisms involving mast cells that bear allergen-specific IgE and that release histamine when encountering allergen. Clinical cases, however, report anaphylaxis in the absence of specific IgE or medical history of allergy. We reported that murine models of anaphylaxis rely on IgG, rather than on IgE, that enable neutrophils, monocytes and basophils, rather than mast cells, to release Platelet Activating Factor following engagement of their IgG receptors. Supporting these findings, allergen-specific IgG are found in anaphylactic patients, and we reported that anaphylaxis in mice expressing a human IgG receptor relies also on circulating myeloid cells.We aim at unravelling the parameters that control anaphylaxis in a novel clinically-relevant model of drug-induced anaphylaxis, strengthened by human-based studies involved patients undergoing drug-induced anaphylaxis in collaboration with clinicians and, altogether, rethink the principles of anaphylaxis. Do allergen-specific IgG concur to anaphylaxis in humans? Do these IgG antibodies regulate IgE-induced reactions? Which IgG receptors are involved? In which tissue does the anaphylactic reaction start? Which cell type(s) are responsible? Among the mediators that are released, which ones are responsible for the shock? Can an anaphylactic reaction be stopped specifically for an allergen? We propose to address these questions by exploiting humanized mice we obtained and by establishing novel models, by visualizing anaphylactic reactions in real time in vivo, by dissecting the cascade of events leading to the shock. Finally, we aim at establishing the proo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Distributed System of Scientific Collections Transition to ERIC Project' (2021-2027) targeting Horizon Europe.

assistant: **Abstract**

The Distributed System of Scientific Collections (DiSSCo) is a pan-European Research Infrastructure (RI) initiative. DiSSCo aims to bring together natural science collections from 175 museums, botanical gardens, universities and research institutes across 23 countries in a distributed infrastructure that makes these collections physically and digitally open and accessible for all forms of research and innovation. DiSSCo RI entered the ESFRI roadmap in 2018 and successfully concluded its Preparatory Phase in early 2023. The RI is now transitioning towards the constitution of its legal entity (an ERIC) and the start of its scaled-up construction (implementation) programme. The primary goal of the DiSSCo Transition Project is to ensure the seamless transition of the DiSSCo RI from its Preparatory Phase to the Construction Phase (expected to start in 2025). In this transition period, the Project will address five objectives building on the outcomes of the Preparatory Phase project:1) Advance the DiSSCo ERIC process and complete its policy framework, ensuring the smooth early-phase Implementation of DISSCo; 2) Engage & support DiSSCo National Nodes to strengthen national commitments;3) Advance the development of core e-services to avoid the accumulation of technical debt before the start of the Implementation Phase;4) Continue international collaboration on standards & best practices needed for the DiSSCo service provision; and 5) Continue supporting DiSSCo RI interim governance bodies and transition them to the DiSSCo ERIC formal governance. The Project’s impact will be measured against the increase in the RI's overall Implementation Readiness Level (IRL). More specifically, we will monitor its impact towards reaching the required level of maturity in four of the five dimen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The first ultra-low extractable silicone film release liner for electronics, silicone adhesive market and medical applications' (XIMOFILM) under Horizon 2020.

assistant: **Objectives**

Today, silicone contamination is one of the main challenges for players of the electronics sector which require the use of Pressure Sensitive Adhesives (PSA). Silicon contamination can drive to 10-20% of defective products. The release liners used for this PSA require low levels of extractible silicone (<20 ng/cm²). Besides, the adhesives used in the electronic market are solvent based. Today, solvent resistant release liners present still high levels of extractible silicone. On the other hand, those release liners with low extractible silicone are not solvent resistant and often do not present high subsequent adhesion. XIMOFILM is also a release liner addressed to the medical sector, where silicone and soft silicone gel adhesives are increasingly used. In this sector the release liners must also present low level of extractible silicones. Founded in 2001, CPI is a spin-off French pioneering company offering complete service for industrial atmospheric plasma integration addressed to professionals of packaging, printing, polymer transformations and textiles. Thanks to the optimisation and industrialisation of our cold atmospheric plasma technology, CPI will offer the first ultra-low extractable film silicone release liners with good release force properties (low) and high subsequent adhesion of the adhesive (more than 90% compared to 65% of current competitors), solvent resistant and with very low silicone contamination (<10ng/cm²). The production cost will be also reduced, allowing to purchasing prices 30% cheaper than our competitors. For this Phase 1, we will focus on the technical and financial feasibility of XIMOFILM process and well define the business model to extend our commercial network to Europe and Asia. For CPI, this project will imply a ROI of 9% in 2024. F