RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Etro-krakow' (1998-2002), addressing dissemination and exploitation.

assistant: **Impact**

The main objective of the conference being organized under the aegis of the European Thrombosis Research Organization, linking scientific institutions across the whole continent, is to facilitate contact and exchange of ideas between prominent scientists and young researchers involved in studies on inherited and acquired disturbances of blood clotting and their role in the development of atherosclerotic blood vessel disease. These disturbances are now viewed not only as a cause of deep vein thrombosis and pulmonary embolism but also as an important cause of coronary heart disease, myocardial infarction, and stroke-primary source of morbidity and mortality in developed countries. Majority of keynote speakers are academic scientists from European Community Member States, while the remaining are from Associated States and the USA. They will deliver plenary lectures and preside over small-group discussions on three key topics of the symposium: 1) Platelet glycoprotein polymorphism, 2) Antiphospholipid syndrome, 3) Hyperhomocysteinaemia. Each topic will be divided into two parts: devoted to laboratory investigations and dealing with clinical studies. Participants from European Community Member and Associated States, as well as from New Independent States and Central and Eastern European countries which are not candidates for accession to the European Union, involved in academic research will present their scientific achievements during oral presentations and poster sessions. At least 25 to 30% of time will be devoted to questions and discussion. The ultimate goal of the conference is to stimulate new international projects and to initiate cooperation between young scientists from different European countries in the field of thrombosis research.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Regulation of normal and pathological activity of cortical networks by cannabinoids: focus on direct modulation of inhibitory GABAA and glycine receptors' (CANNABISTARG), addressing dissemination and exploitation.

assistant: **Impact**

Cannabinoid signaling is ubiquitous in the brain, but until now the focus has been on G-protein coupled cannabinoid receptor (CB1R) mediated effects. Recently growing number of studies report that cannabinoids at physiologically relevant concentrations can modulate the functional properties of a number of ligand- and voltage-gated ion channels, independent of CB1R activation. However, so far the importance of this pathway in cannabinoid signaling remains largely underestimated. Our new findings show that cannabinoids can act as direct neuromodulators of the GABA and glycine receptors. The newly discovered direct interaction of cannabinoids with inhibitory receptors displays features which differ from the CB1R-dependent modulation, therefore it may have completely different, so far unexpected, impact on neuronal activity. It is generally accepted that the balance between synaptic excitation and synaptic inhibition is essential for network activity and information processing. Epilepsy is one of the most common neurological disorders affecting 2% of the world’s population, in which normal brain function is disrupted as a consequence of intensive and synchronous burst activity from neuron assemblies. At present ~30% of epileptics are not adequately controlled with conventional drugs due to development of tolerance and pharmacoresistance, therefore justifying the search for new antiepileptic targets.We hypothesized that direct modulation of inhibitory synaptic transmission by cannabinoids might have high impact on initiation and development of the epileptoform activity and may provide effective tools for controlling the network function.Using multidisciplinary approach within the proposed project we will investigate the molecular mechanisms underlying CB1R-independent intera
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Processing Systems with Optical Delay' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The primary goal of this project is to train a talented young researcher, Dr. Marina Zajnulina, with a strong academic background in nonlinear fibre and semiconductor optics, laser physics and general nonlinear-wave theory, through a research programme focused on developing of novel all-optical processing systems based on ultra-short fibre lasers, and their usage in a range of practical applications. There is high demand in ultra-short fibre lasers, because they are highly desirable as light sources due to their flexibility, simplicity and cost-efficiency. The project will include theoretical, experimental, and numerical studies of optical ultra-short pulse generation and propagation in a processing system based on an ultra-short fibre laser with optical feedback. To guarantee an all-over success of the project, several European world-leading academic and industrial (non-academic) partners will participate in the project as secondment hosts and co-hosts and consultants. The success of this project will contribute knowledge to the fields of laser science and technology, and establish an internationally leading position for Europe in the industrial applications relevant to telecommunications, as well as other high-demand fields such as spectroscopy, frequency metrology, and instrument calibration. Further, this project will explore the commercialisation of a novel laser as a processing system and enable a greater market share for fibre laser applications. A long-term collaboration between the Fellow and the host and co-hosts will be established ultimately resulting in a new level of optical processing and laser devices and technologies and enhancing the European leading position in this highly competitive commercial field.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'ClC-5 regulation and endocytosis at the renal proximal tubule or molecular bases of Dents disease' in the context of a Sixth Framework call.

assistant: **Objectives**

Mutations in the gene encoding ClC-5, an electrogenic Cl-/H+-exchanger, cause a renal syndrome called Dents disease, which is characterized by genetic heterogeneity lowmolecular weight proteinuria, hypercalciuria, nephrolithiasis and progressive renal failure.By generating a ClC-5 knock out mouse, Thomas J. Jentsch and coworkers demonstrated that the loss of ClC-5 diminishes receptor-mediated and fluid-phase endocytosis. As ClC-5 provides an electrical shunt for the electrogenic pumping by the H+-ATPase, it is believed that the impaired acidification of endosomes causes the defect in endocytosis.However, other mechanisms such as direct protein-protein interactions in endosomes have not been excluded. The defective proximal tubular endocytosis is associated with an improper trafficking and/or downregulation of several key proteins for kidney physiology such as the megalin endocytotic receptor, NaPi-2 Na+-phosphate cotransporter and NHE3 Na+/H+ exchanger.Thus ClC-5 plays a major role in kidney physiology and serves as a paradigm to understand the role of vesicular acidification in endocytosis in general. The regulation of ClC-5 and its interaction with other proteins are poorly understood. However, it has been shown that ClC-5 interacts via a PY motif with certain HECT-ubiquitin ligases.I propose to further characterize the ubiquitylation of ClC-5 and to study the mechanisms by which it influences its localization and endocytosis. In addition, I would like to search for and test several putative interaction partners of ClC-5 in order to better understand the molecular bases of Dents disease and its genetic heterogeneity.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Accurate crystallography of heavy-fermion-superconductors at high pressure and low temperature' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

This project is concerned with accurate crystallographic measurments on heavy-fermion superconductors as a function of pressure and temperature. High accuracy structural studies are needed to complete measurements of superconducting, transport and optical properties - all observed under pressure - to allow a comparison with theory. Precise compressibility measurements will first be made on single crystals and powders, detailed crystallography will follow. The materials of interest are UPd2A13 and UNi2A13 of the U-based and CeCu2Si2 and CeCu2Ge2 of the Ce based heavy-fermion superconductors. These high-resulution, high-sensitivity structural measurements will be made using the unique high brilliance X-ray beams available at the ESRF in Grenoble. There, wavelength-tunable, focussed monocromatic beams are used with area detectors to collect high quality two-dimensional images. From these reliable intensity data accurate crystallographic information can be obtained. In addition, existing collaboration between the ESRF and experts in the fields of high pressure cells and cryostats will ensure the availability of the state-of-the-art environment facilities required for this project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Studies of exotic nuclei using tagging spectrometers' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

Description:Objectives: The objective of the project is to develop recoil implantation spectrometers that can be used in conjunction with recoil separators employed in several research infrastructures, such as RITU at Jyväskylä, SHIP, FRS at GSI, LISE, VAMOS at GANIL, and directly with radioactive beams produced by REX-ISOLDE at ISOLDE, CERN. This will require several parallel developments of nuclear instrumentation having a common requirement of highly segmented Si- and Ge- detectors and associated pulse processing electronics. The prototype detectors will be developed by the consortium of institutions. The program involves simulation modelling, design, construction of detectors and associated electronics followed by test experiments and application to real in-beam experiments.Results:EXOTAG workshops:Particle Identification Techniques" CERN, September 28-29, 2000"Conversion Electron Spectroscopy Techniques" Jyväskylä, February 16-17, 2001"Electronics and Data Acquisition Developments for Tagging Experiments", Daresbury, October 18-19, 2001"JuroGam for Tagging Experiments", Jyväskylä, November 22-23.2003"Rex ISOLDE Workshop", CERN, December 16-18, 2002"Workshop on conversion electron spectroscopy and tagging methods", Bonn, January 23-24 2003The hybrid Si- detector system designed and constructed in Liverpool and at RAL, Daresbury together with a new type of triggerless data acquisition system was commissioned at JYFL in Jyväskylä,. New pulse shape electronics has been developed at GSI: Evidence for new radioactive mode, 2-proton emission from the ground state of 45Fe has been found. New pulse shape analysis methods based on wave-lets have been investigated.Project Manager:Rauno JulinDepartment of Physics, University of Jyväskylä, (JYFL)P.O. BOX 3540351 Jyväskylä, Finl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Response of benthic communities and sediment to different regimens of fishing disturbance in European coastal waters' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

REPONSE is an integrated strategy to know the response of the biotic environment structure and the changes of the particulate matter dynamic, caused by the disturbance of fishing activity. This research is focused to provide new perspectives and management options to the CFP in order to achieve sustainable fisheries and of protection of biodiversity, a widely recognised problem in moving towards ecosystem-based management in fisheries.The main objective is to obtain more knowledge on mid and long-term effects to different regimens of fishing trawl perturbation on the seabed, analysing cessation of fishing activity and different levels of fishing effort. The study will be performed in real fishing grounds of the European coastal waters. The objectives will be achieved with 6 multidisciplinary workpackages, by estimation of changes in sedimentologic process, benthic and fish community, and secondary production of the lower trophic levels.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Coordination and Collaboration between reference collections of plant pests and diseases for EU Plant Health Policy'.

assistant: **Innovation**

International trade is increasing tremendously in recent years with a lot of import and export material going in and out of the European Union. Within this context there is also the increasing risk of importing unwanted organisms via this trade. Organisms include plant pests and pathogens, some of which may be on the quarantine list of the European Union. Also climate change may increase the ability of plant pests to survive regions other than those of their origin. Within the field of Plant Health a decline in taxonomic and phytosanitary experience has become eminent in the last decade; also relevant phytosanitary collections are under pressure. This will affect all members of the EU and other nations as well. To regulate and control plant pathogens there is an increasing need for efficient and reliable identification and detection tools. For their development and validation, good and well maintained collections containing relevant species are indispensable. A significant number of plant pest collections are still present within Europe but they are dispersed, widespread and of very variable quality. NPPO’s, mandated laboratories, universities and research institutes all have their own collections related to their specific work and scope. Many of these collections are connected to a single specialist. Within Europe there is a need to improve the infrastructure supporting phytosanitary important collections so as to more efficiently use the available infrastructure and improve collaboration in the field of phytosanitary infrastructure with regard to means, knowledge, expertise on taxonomy, development of detection methods and collections of phytosanitary important organisms.  The main outputs to be disseminated from the project will include an inventory on characteristic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'A Cognitive Serverless Framework for the Cloud-Edge Continuum' (2021-2027) targeting Horizon Europe.

assistant: **Abstract**

An effective platform for the cognitive cloud-edge continuum must address a number of unsolved challenges, many of them derived from constrained resource devices, infrastructure heterogeneity, and the need to meet criteria such as performance, resilience, security, data sovereignty, and energy efficiency. A disaggregated architecture is required, making use of AI, automation, and portability to manage and adapt resources and workloads, and to respond in real time to possible incidents and security threats. Edge application developers willing to speed up computation, save energy, and cut costs will need a way to combine their edge devices with the many resources available across the cloud-edge continuum. This innovative approach requires computationally-intensive data processing functions to be easily executed outside edge devices, sensors, and actuators. It is with that vision in mind that this project proposes a new distributed Function-as-a-Service (FaaS) paradigm for edge application management and smart orchestration, which will change how applications and services are deployed and executed in the cloud-edge continuum. Our AI-enabled adaptive serverless framework will provide applications with secure and portable access to a continuous data processing environment that abstracts the large-scale, geo-distributed, and low-latency capabilities provided by the cloud-edge continuum.The Consortium combines innovative open source companies in Europe, high-impact research organizations, and several edge application providers. Our research will be validated in relevant application domains, and will establish an ecosystem with links to industrial initiatives. This project will be transformative for the emerging EU edge ecosystem, providing resources and knowledge for start-ups
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Low Cost and low Energy GNSS-based WIreless Tag for asset Tracking and monitoring' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Nowadays, all long range asset tracking applications make use of the GSM/GPRS network to transfer the position of the items being monitored at regular intervals to treatment servers and end-users. These communication channels call for expensive subscriptions with telecom operators which limit their use to those applications which are worth the investment either from an economic or safety standpoints. Yet, many additional ‘tracking’ applications could be envisaged provided that long range communication costs could be decreased.The SigFox Wireless company has developed the TransFox Ultra Narrow Band technology which brings drastic enhancements in terms of range, capacity, autonomy, power consumption and total system cost, compared to competing technologies. Targeted to be deployed as a wide area wireless communication system, the technology allows offers higher coverage than GSM/GPRS with the same output power as WiFi or Bluetooth.The STERELA company benefits from a strong market positioning for traffic counting and road data collection equipment. Based on its market knowledge, STERELA is convinced of the opportunity to combine such new radio-communication systems with their own leading edge expertise in low consumption electronics to open new GNSS applications in the road area.In this overall context, the CEWITT project aims at developing an innovative wireless tag and the associated SIGFOX wireless communication and GNSS geo-positioning capabilities with the objective to ensure the integrity and cost effectiveness of Pay per Use parking & Identification of free parking slots applications in Urban Areas.The optimisation of EGNOS / GPS capabilities, map matching techniques, correlation with SIGFOX signals and the development of specific algorithms working on EGNOS correct
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Controllable global illumination for film production' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The ultimate objective of the project is to start a new interdisciplinary computer graphics research group in the return host under the direction of the fellow. This leading position will allow him to fully exploit the skills acquired during the outgoing stage at the renowned Cornell University Program of Computer Graphics, and will be the foundation of his long-term independent research career.  The central source of the new skills will be the execution of the proposed research, where our goal is to allow the artists in film production to create more compelling realistic computer-generated imagery through establishing global illumination as a common tool for image rendering.  To reach this goal, we propose several novel scientific aspects, the most significant being the study of visual importance of various distance components of light transport on the perceived quality of synthetic images. Results of this study will drive the design choices in our development of new algorithms and data structures, such as: a) new illumination caching strategies for efficient global illumination computation in scenes with complex geometry and materials, b) memory-efficient representation of the light transport operator for real-time relighting in cinematic lighting design. In addition, a novel interface will be developed to provide artistic control over global illumination computation.   The proposed research, encompassing several disciplines, such as psychophysics and cognitive sciences, statistical data modeling, and human-computer interaction, is designed specifically to deepen and widen fellow’s expertise and add to his multidisciplinary skills.