RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Genetic analysis and manipulation of the extracellular polysaccharide biosynthetic pathway in lactic acid bacteria'.

assistant: **Objectives**

Research objectives and content The objective of the project is to genetically engineer LAB strains to generate novel polymers with improved properties for food industry. Such strains could be used not only in the fermentation of milk products with novel properties, but also as sources of polysaccharide for use in other foods, for example, as ingredients for use as thickeners stabilizers. The content of the project will be: identification of remaining genes involved in polysaccharide biosynthesis in Streptococcus thermophilus NCF2393; inactivation of selected genes resulting in the generation of polymers with novel primary structure; harvest and structural analysis of the polymers; transfer of genes required for EPS biosynthesis in S. thermophilus , to other microorganisms of industrial relevance; evalution of the potential for improving textural properties. Training content (objective, benefit and expected impact) The objective for the Grant is providing the student with a wide training in all the key areas of Genetics and Molecular Biology. Benefits will also include acquring experience of interdisciplinary team work through collaboration with other research groups; and attendance and presentation of work at seminars and lectures and abroad conferences. Links with industry / industrial relevance (22) The Group has several links to industry (eg. AMBI provides partial financial! support). Discussions relative to the research project are underway though are of confidential nature.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Prudenta: Electronic Solution for Safer Drugs' (2014-2020) under Horizon 2020.

assistant: **Objectives**

Prudenta is an innovative, artificial intelligence-supported cloud-based solution that will enable pharmaceutical companies to automate local medical literature monitoring for drug safety signals (possible adverse reactions) and thus drastically improve the safety of drugs, as well as reduce the costs of drugs in the market. Safety signal searching is mandatory by law to all pharmaceutical companies and must be performed in each country, where the drug is traded. Until now - such searching was manual, in many instances not even electronic. If successful, Prudenta would have a three-fold impact: 1) Safer drugs due to automation of the process and exclusion of the human error; 2) Cheaper drugs due to reduction of costs of inefficient use of experienced and educated personnel in pharmaceutical companies for manual searching; 3) Increase in employment in EU for support of all Prudenta activities (software development, operations, sales & marketing, etc.).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'A new process to improve gas turbine engine performance by thermal barrier coating technology' under Fourth Framework.

assistant: **Concept**

Objectives and content:The objective of the PROTECT project is to develop an industrially usable process for deposition of high quality Thermal Barrier Coatings (TBCs), which meet industry specifications, onto gas turbine blades by Chemical Vapour Deposition (CVD) technology. To achieve this aim a research consortium of 5 industrial partners and 2research centres have come together to share resources and expertise. The project will initially focus on laboratory scale development of CVD techniques to deposit TBCs having the crucially important columnar structure, which contributes to good thermo-mechanical stress resistance in service. Specially selected organo-metallic precursor chemicals will be used. The process will be optimised to produce acceptably high deposition rates and carbon free coatings with uniformity of thickness. A specialist CVD equipment manufacturer will design and construct a pilot scale CVD reactor and a commercial coating company will optimise the new process at pilot scale. Turbine blades, with thermal barrier coatings deposited by the new process, will be rigorously tested to industry specifications by the research centres and by the partner who is a gas turbine manufacturer. The industrial partners involved in PROTECT consist of a gas turbine manufacturer, a company which provides a coating service to the gas turbine industry, an end-user in the power generation industry, an equipment manufacturer and a specialist chemicals manufacturer. They are well positioned to exploit the new technology in the land based and the aero gas turbine sectors, thus contributing to increased engine efficiencies and reduced fuel consumption. BE97-4634
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Wall-crossing and Birational Geometry'.

assistant: **Objectives**

We will use modern techniques in algebraic geometry, originating from string theory and mirror symmetry, to study fundamental problems of classical flavour.  More concretely, we apply wall-crossing in the derived category to the birational geometry of moduli spaces.Bridgeland stability is a notion of stability for complexes in the derived category.  Wall-crossing describes how moduli spaces of stable complexes change under deformation of the stability condition, often via a birational surgery occurring in its minimal model program (MMP). This relates wall-crossing to the most basic question of algebraic geometry, the classification of algebraic varieties.Our previous results additionally provide a very direct connection between Bridgeland stability conditions and positivity of divisors, the main tool of modern birational geometry.  This makes the above link significantly more effective, precise and useful.  We will exploit this in the following long-term projects:1. Prove a Bogomolov-Gieseker type inequality for threefolds that we conjectured previously. This would provide a solution in dimension three to well-known open problems of seemingly completely different nature: the existence of Bridgeland stability conditions, Fujita's conjecture on very ampleness of adjoint line bundles, and projective normality of toric varieties.2. Study the birational geometry of moduli space of sheaves via wall-crossing, adding more geometric meaning to their MMP.3. Prove that the MMP for local Calabi-Yau threefolds is completely induced by deformation of Bridgeland stability conditions. The motivation is a derived version of the Kawamata-Morrison cone conjecture, classical questions on Chern classes of stable bundles, and mirror symmetry.4. Answer major open questions on the  birational
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'A Coordinated Action towards the promotion and consolidation of all RTD activities for large-scale integration of DER in the electricity market' in the context of a Sixth Framework call.

assistant: **Objectives**

The integration of DER in the European electricity networks has attracted attention of energy producers, network operators, policy makers and R&D community. In some countries it created a number of challenges for the electricity supply system creating barriers for further expansion of DER. Furthermore, there exists a lack of awareness and understanding of the possible benefits and scope of DER in the electricity system, while environmental goals and security of supply issues ask for solutions that DER could give in the future. The SOLID-DER Coordination Action will tackle the barriers for further integration of DER, overcoming the lack of awareness and fragmentation in EU R&D results by consolidating all European DER research activities. In particular awareness of DER solutions and benefits will be raised in the new Member States, thereby addressing the specific issues and barriers faced here. Consequently the key objectives of the project are: Identify and assess the critical developments, innovations and findings in meeting the R&D needs for large-scale integration of DER. It concerns developments in the field of legislation, regulation, DER support policies, market access, technical breakthroughs in DER supply and enabling technologies. To provide an assessment of costs/benefits and concepts of business models for DER and pro-active networks. Raising awareness of benefits of DER and organising dissemination of knowledge and capacity building in the new MS. The assessment and recommendations of RTD activities and its progress on national, regional, and EU levels will be reviewed and commented by the representatives of the electricity business community. This intensive dialogue will lead to an effective achievement of the overall EU energy policy goals and optimising t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Laboratory studies And Modelling Of heterogeneous Chemistry in the Stratosphere'.

assistant: **Objectives**

This research project is a joint laboratory and modelling study of heterogeneous chemical processes which take place on stratospheric sulphuric acid aerosol (SAA) and which influence the partitioning of hydrogen, halogen and nitrogen species in the lower stratosphere over middle to high latitudes. The main goals of the project are to illucidate: A. Fundamental physico-chemical properties of the stratospheric sulphate aerosol: - Chemical speciation and oxidative capacity (neutral and ionic components) - Diffusion coefficients - Uptake coefficients (sticking coefficients) - Henry's law constants - Solvent effect on UV spectra and photolysis products of dissolved trace gases. B. Chemical reactions in or on the sulphate aerosol: - Conversion of NO3 radicals which may result in a nighttime production of H2O2 - Reaction of ClOOCl with halogen ions which may convert HCl into ClO and OH - Oxidation of ClO and BrO to higher halogen oxides. - Reaction of ClONO2 with H2O2 to form ClOOH - Reactions of N2O5, BrONO2, BrCl, etc. - Calculation of spectroscopic and thermodynamic parameters for chemical compounds and reactions not easily accessible to laboratory studies. C. The impact of heterogeneous chemical reactions on stratospheric ozone depletion by modelling: - Parameterisation of (new) heterogeneous chemical reactions for use in models of the stratosphere. - Sensitivity tests of the individual reactions studied in the laboratories by the use of 2D- and trajectory models of the stratosphereAll laboratory investigators in the project will use a common reaction medium of a composition close to that  of the stratospheric aerosol at mid-latitude, i.e. 60-80 wt % sulphuric acid in water with trace constituents added  in the right proportions. The surface of the laboratory SAA mimics wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Uncover and promote tolerance to temperature and water stress in Camelina sativa' under Horizon 2020.

assistant: **Concept**

European agriculture is increasingly challenged by climatic variability and weather extremes causing drought and temperature stress to crops that are very often highly sensitive to abiotic stress conditions, resulting in low productivity and yield loss. Camelina sativa is a reemerging native European oilseed that has retained its natural stress tolerance and receives attention because of its untapped breeding potential, adaptability, yield stability and high performance in variable environments. UNTWIST will unravel the stress response mechanisms of the climate-resilient crop Camelina and reveal its successful stress adaptation strategies for implementing them in new agronomic solutions. UNTWIST brings together a unique consortium with complementary expertise in stress mechanisms, (epi)genetic regulation, physiology, metabolism, crop modelling, and crop management to drive biological discovery. Stakeholder expertise by three SMEs will allow smooth knowledge transfer into crop improvement and new management strategies. UNTWIST will use genetically diverse Camelina cultivars in open field and stress-controlled experiments together with sophisticated systems-based approaches to uncover the plants adaptive multi-layered stress response mechanisms. Complex data integration will provide genome scale models revealing plant strategies for managing uncertainty and a validated accurate model to predict crop performance in variable environments. Moreover, UNTWIST will deliver new tools and markers for effective translation into other crops. Finally, UNTWIST will meet the climate challenge in agriculture by providing elite-adapted Camelina germplasm and developing agronomic management practices for ready adoption by farmers into new climate resistant cropping systems.


**Keywords:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The neural dynamics of perceptual priors in audition' (PriorDynamics).

assistant: **Concept**

To maintain a coherent and continuous percept over time, the brain relies on past sensory information to predict forthcoming stimuli. Combining novel behavioural methods with advanced neuroimaging techniques, the present research project aims to determine the neural mechanisms by which the auditory system uses information from the recent past to overcome signal noise and ambiguity. Specifically, we test the hypothesis that sensory predictions involve neural oscillations at alpha rhythm, ~9-10 Hz, that mediate the propagation of perceptual priors. The first part of this research project investigates the neural structures underlying such predictive oscillatory mechanism. To this end, we adapt a novel time-resolved sampling technique used to examine rhythmic fluctuations in perceptual performance for functional magnetic resonance imaging (fMRI). We hypothesise that cortical and subcortical activation, especially in the auditory cortex and thalamus, will exhibit rhythmic modulations that correlate with oscillations in decision bias during the detection of a brief auditory signal masked by white noise. The second part of this project examines whether the resolution of perceptual ambiguities by prior contextual information involves similar oscillatory mechanisms. For this purpose, we combine the time-resolved sampling technique with a classic paradigm (involving Shepard tones) for inducing ambiguous pitch shifts. By presenting a single tone before the ambiguous stimulus, listeners can be biased toward a perceived upward or downward pitch shift. If resolving perceptual ambiguities involves oscillatory mechanisms, we expect to observe periodic fluctuations of decision bias (that is, the tendency to make certain responses) at alpha rhythm over time. The results of this research
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Development of monotoring quidelines and modelling tools for environmental effects from Mediterranean aquaculture' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

OBJECTIVES AND EXPECTED ACHIEVEMENTSIn northern Europe, Canada, Tasmania and recently in Chile, considerable efforts have been made to assess interactions between aquaculture and the environment. Most models, guidelines, monitoring procedures, and environmental quality standards are, however, directed toward salmon farming. Although scientific knowledge on the impacts of salmonid farming has progressed substantially, very little is known of fish farming impacts in the Mediterranean. In the last decade aquaculture of sea bass (Dicentrarchus labrax) and gilthead sea bream (Sparus auratus) has experienced a period of exponential growth in the Mediterranean region. This process needs to be controlled in order to ensure a sustainable development of the aquaculture industry and to consider other aspects of an integrated management of the coastal zone, including tourism, fishery, and environmental protection.Established guidelines for an initial impact assessment need to be complemented by subsequent impact monitoring.Despite the rapid development of aquaculture in coastal areas of the eastern Mediterranean little has been published on the environmental impacts of this industry. Also, protocols, monitoring systems and techniques for the control of marine cage fish farms in Mediterranean conditions do not currently exist. In general, it has been assumed that these will, at least qualitatively, follow the pattern established in northern latitudes. Strategies developed and proven for salmon culture in northern Europe and elsewhere deliver comprehensive concepts, but need to be modified and adapted to the ecological particularities of the Mediterranean Sea. In addition to differences in the species cultured, the climate, the current regime, and the level of eutrophication, differe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Cystic fibrosis: rescue of the function and of the processing of cftr mutants by pharmacological agents and by interacting proteins (CF-PRONET)' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

Mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) affect the maturation and trafficking of the protein in the cell or cause dysfunction of this cell surface expressed chloride channel. To rescue the cells, compounds will be designed capable of correcting the processing and dysfunction of CFTR. In addition known interacting proteins and novel interacting proteins, identified during the proposed investigations will be characterized at the genetic, biochemical and electrophysiological level and their ability to compensate for or rescue the cells from dysfunction will be determined (in combination with selective compounds) . The thus identified protein network should contribute to the understanding of the clinical variation observed in affected sibs, the role of similar mutations in the frequent CF related diseases and could provide tools to diagnose, monitor and treat these diseases.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'DIVERSIFY : Ecology-inspired software diversity for distributed adaptation in CAS' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Biodiversity is essential for the robustness and adaptability of ecological systems. Similarly, multiple theoretical and experimental scientific results emphasize the need for high levels of diversity for the wealth of other forms of complex systems (e.g., economy or social communities). In the face of these numerous scientific evidences, the limited amount of diversity in software that constitutes collaborative adaptive systems (CAS) is a major concern. This is particularly critical since CASs are complex systems that integrate multiple concerns, interact with the physical world and need to adapt to unforeseen evolutions and perturbations.<br/>DIVERSIFY explores diversity as the foundation for a holistic software design principle and increased adaptive capacities in CASs. Higher levels of diversity in the system provide a pool of software solutions that can eventually be used to adapt in front of a situation unforeseen at design time. The scientific development of DIVERSIFY lays in a strong analogy with ecological systems, biodiversity, and evolutionary ecology. DIVERSIFY gathers researchers from the software-intensive, distributed systems and the ecology areas in order to transfer ecological concepts and processes as software design principles.<br/>DIVERSIFY's aims at establishing novel principles and techniques to increase software diversity levels in CASs and to leverage this diversity for distributed adaptation. The consortium's ecology group will drive the transfer of ecological processes in software. Software diversity synthesis and adaptation will leverage model-driven approaches to deal with the heterogeneity of entities in CASs. The project will develop a CAS simulator in the domain of smart cities to reveal the role of software diversity in CASs and to establ