RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'PRIFOG - A technology-powered producer responsibility initiative for fat, oil and grease compliance for food service outlets', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Evolution Environmental Services Ltd (EES) is an environmental consultancy business that provides outsourced fat, oil & grease (FOG) source control programmes to city authorities in Ireland. FOG is a major contributing factor to sewer blockages in urban areas that poses challenges to sewer asset managers, and adversely affects citizens in cities worldwide. To combat this problem, many cities impose regulations on food service outlets (FSOs) in the form of a FOG source control program. However satisfying these regulations places a significant financial and operational burden on food service outlets.The goal of this Action is to develop a feasibility study for PRIFOG, a technology-based producer responsibility initiative for FOG compliance. PRIFOG’s cloud based software solution provides a platform that connects the city authority with the FSO and allows both stakeholders to manage, verify and validate compliance online. PRIFOG fosters a positive relationship between FSO’s and the city authority by providing independent advice, guidance, training and promoting best practice for FOG compliance. The feasibility study of PRIFOG will be completed by delivering four key objectives; 1) conduct a detailed market analysis, 2) proof of concept pilot study within the Irish market, 3) develop a detailed product roadmap based on customer needs, and, 4) develop an elaborated investor-ready business plan to scale the PRIFOG solution to international markets.PRIFOG uses emerging technology to address two problems that are replicated in almost every city worldwide. Firstly, PRIFOG reduces the problems caused by FOG in drainage networks. Secondly, PRIFOG provides a solution that reduces the burden of regulation on FSOs.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Nanomechanics of proteins involved in viral and bacterial infections' (INFEMEC) targeting Seventh Framework.

assistant: **Abstract**

Viruses and bacteria utilize proteins to attach and infect cells and tissues. Viruses have envoloped proteins that especifically recongnize receptors in the surface of the target cells. HIV-1 recognices receptor CD4 in the surface of T cell throghout its envolope glycoprotein gp120. In the case of bacteria, they attach to tissues using long filament called pilus. Bacterial pilus type 1 is composed of several protein subunit arranged in chain, FimA-FimG-FimG-FimH. The more external domain, FimH, is the adhesin binding domain that establishes the mechanical anchoring to tissues. Both, bacterial and viral proteins withstand mechanical forces than can go from few piconewtons to hundreds. However, very little is known about how force modify the structure and features of these proteins and ultimately how its affects infection. In this project we aim to investigate the effect of mechanical forces in the anchoring proteins and its role during attachment. We will concentrate in viral receptors CD4 and bacterial fimbriae proteins (Fim). We will use a novel atomic force spectometer that allows us to apply calibrated forces to a single protein molecule. This technique allows also monitoring chemical reaction under force such as the reduction of disulfide bonds or the binding of peptides and antibodies. These processes are known to be implicated in the infection of viruses and bacteria and they may have a mechanical origin. We will use bioinformatics and high-throughout screening techniques to identify molecules that alter the nanomecanichs of these anchoring proteins and that can potentially be used to prevent infections.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Development of a cost-effective moisture and thermal barrier layer for protective clothes based on an innovative combination of warp-knitted textiles and hydrogel polymer coatings, introducing new standards which will prevent low quality im' (2002-2006), addressing dissemination and exploitation.

assistant: **Impact**

To address the issue and minimise accidents EU launched directives 89/656/EEC and 89/686/EEC, which oblige employers to make available protective clothes to their employees. Since than the market of protective clothing has been therefore boosted. 98% of the 20000 European companies involved in the protective clothing value chain are SMEs, which are suffering competition from India, China, Japan and Taiwan. As a result non-EU imports in the last 5 years have increased by 34% resulting in a reduction of employment in Europe by 14%.This is a highly relevant problem for the SME proposers and more in general for the entire European sector. Wearing state of the art protective clothing for indoor work in non-ventilated areas, in hot temperatures or performing physically demanding work hinder a worker ability to remain cool. Workers inability to shed excess heat results each year in 1500 heat strokes in Europe. Less serious consequences of heat stress are more common, affecting 50000 workers per year all over Europe. Our objective is to develop a thermal and moisture management layer based on a 3qweft-knitted flameproof fabric coated with a hydrogel polymer, fully compliant with EU directive 89/656/EEC and 89/686/EEC and standards UNI EN 470-1. This structure, that will replace the thermal layer and moisture barrier in typical three-layered protective clothing fabric, mimics physical mechanisms for human body thermoregulation. This concept has been validated through a feasibility study performed by the partners. However barriers need to be overcome through the achievement of the following scientific and technical objectives:1) development of a knowledge-based design tool able to predict the peculiar mass and heat transfer flows through the proposed system,2) design and modellin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'HSC-based therapies for LSDs: understanding the modalities of cell replacement in the LSD brain for improving therapeutic efficacy'.

assistant: **Objectives**

The recent hypothesis that postnatal microglia are maintained independently of circulating monocytes by local precursors that colonize the brain before birth has relevant implications for the treatment of various neurological diseases, including lysosomal storage disorders (LSDs). LSDs are fatal diseases of childhood occurring in 1:5000-7000 live births; in >50% of the cases, LSD patients experience a severe neurological deterioration. Most LSDs with central nervous system (CNS) involvement lack a curative treatment. Hematopoietic cell transplantation (HCT) form healthy donors is applied to LSD patients in order to repopulate the recipient myeloid compartment, including CNS microglia, with donor-derived cells expressing the defective functional hydrolase. Over the past three decades, about 1000 HCTs have been performed for patients with LSDs with a variable benefit exerted on the CNS. The positive results obtained in Hurler syndrome and few other LSDs and the benefit observed in our on going Phase I/II clinical trial of HSC gene therapy for the demyelinating LSD metachromatic leukodystrophy indicate that migration of the transplanted Hematopoietic Stem Cells (HSCs)/their progeny into the affected human brain occurs. However, timing of resident CNS macrophages and microglia replacement by the transplanted cell progeny is frequently too slow for clinical benefit due to the rapid progression of the primary neurological disease, particularly in the most aggressive LSD variants. Thus, a deep understanding of the modalities, time course and factors that affect this phenomenon might allow enhancing clinical benefit of HSC-based approaches for treating the LSD brain disease. The proposed work, combining basic and innovative preclinical research with the information derived from
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Repair of Injured Spinal Cord' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Currently, there are approximately 200,000-250,000 para- or quadriplegics in the EC, most of whom became disabled in early adulthood as a result of traffic or sporting accidents. Traumatic spinal cord injuries encountered in neurosurgical practice are highly heterogeneous due to a variety of factors : e.g. open or closed nature of injury ; segmental level of injury (ranging from upper cervical to conus level) ; possible association with bone lesions leading to prolonged cord compression ; possible association of root avulsion; possible association with dura mater dilaceration or impaction within the spinal tissue. Throughout the last century, there has been a consensus of opinion amongst physicians, surgeons and rehabilitation specialists that severed spinal cord injury invariably leads to motor function deficit and severe disability. The doctrine of abortive sprouting" established by Ramon y Cajal in the early 20th century has only recently been challenged. The work of David and Aguayo (1981) indicated that spinal neurons possess an intrinsic capacity to regenerate provided that they are presented with an environment which is permissive to axon growth. The last decade has witnessed a surge of intense scientific activity in the field of CNS regeneration. The spinal cord is the model of choice since the clinical syndrome induced by spinal cord injury is very specific. Also, the well known anatomical organisation of the spinal cord as the principal conduit for motor, sensory and autonomic pathways permits correlated anatomical, biochemical and functional studies. We have two main objectives : to study the pathophysiological mechanisms at the site of injury and to develop strategies for their management. At the lesion site there are specific problems, such as the disruptio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Tick-borne encephalitis Targeted by Human Active NK cells' under Horizon 2020.

assistant: **Concept**

The aim of this project is to determine the role of natural killer (NK) cells, effector players of the innate immune system that target virally infected cells and tumor cells, in the infectious disease Tick-borne encephalitis (TBE). By elucidating their function either in enhancing or suppressing the disease in two different compartments, central nervous system (CNS) and peripheral blood, we seek to generate knowledge that will provide new insights into innate immunity that could lead to novel strategies to improve treatments for infectious diseases.This project is intended to take place mainly in the Center of Infectious Medicine from the Department of Medicine at Karolinska Institutet (KI) in Stockholm. To complement the scientific training proposed, a secondment of two months will be carried out at the VU University Medical Center in Amsterdam, Netherlands. Overall, the goal of the present application is to support the restart of the scientific formation of the applicant, who has made a 2-year career break due to maternity leave. The short-term objective of the current study is to provide training of the researcher in advanced cellular characterization, labeling, and bio-imaging techniques, synergistically with trans-European mobility, reinforcing her scientific, managerial and leadership qualities. A mid-term objective is the progress of the researcher’s career in science and the broadening of her scientific horizons, and a long-term aim is the Fellow’s setting as an independent investigator.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'GMES - forum organisation user requirements' to be submitted under Fifth Framework.

assistant: **Abstract**

G-FOUR project will establish a continuous and bi-directional information flow between GMES stakeholders, by organising GMES conferences during the next 4 EU presidencies associated with users consultations. This will provide a set of structured recommendations resulting from user consultations as a basis for future actions on research needs and infrastructure requirements and will develop a common vision for GMES enabling stakeholders to understand what could be delivered by 2008. Staged approach will allow results to be obtained after the 2nd, 3rd and 4th conf. and therefore enables calls for research projects be launched by EC and ESA in early 2004. The project will rely on a Technical Committee composed of senior scientists external to the consortium with renowned expertise in GMES domain, TC will ensure technical consistency and maximum synergy between WPs, and independence of recommendations issued by the project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Just Transitions for Sustainable Astronomy' (SKYJUST).

assistant: **Concept**

To accelerate a just and inclusive transition towards a carbon neutral and green economy (European Green Deal) the EU is boosting its research area and heavily investing in the modernisation of its Research Infrastructures (RIs). To fill the gap on how scientific agencies are adopting transitions policies in their RIs, SKYJUST examines two intergovernmental astronomical agencies with strong European participation, the European Southern Observatory (ESO) and the Square Kilometre Array Observatory (SKAO) with multiple large-scale RIs in the Global South. These are excellent cases to produce an overview of European sustainability policies for astronomical RIs, understand the agencies’ everyday narratives and practices of sustainability transitions, provide policy recommendations, and develop an original conceptual framework bridging coloniality studies and Multi-Level Perspective on transitions. Through a pool of interdisciplinary methods SKYJUST develops an empirical analysis of how the dimensions of environmental sustainability, coloniality and governance are embedded in ESO and SKAO RIs in Chile, South Africa and Australia. Training, mobility and collaboration with world-leading scholars in transitions, decoloniality, and sustainability governance will boost my career as a world-class researcher, through courses at UU, a secondment at UCL (UK) and short visits to research centres in the Global South. Through a sound dissemination and communication strategy, SKYJUST seeks to produce an impact in the research agenda on RI’s sustainability, and deliver evidence-based policy recommendations to include a non-colonial Just Transition approach into EU’s RIs roadmaps and astronomical agencies and industry, fostering long-term sustainability partnerships between the EU and its l
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Development of a Portable Internal Reforming Methanol High Temperature PEM Fuel Cell System' (IRMFC).

assistant: **Concept**

The complexity of the balance of plant of a fuel cell-fuel processor unit challenges the design/development/demonstration of compact and user friendly fuel cell power systems for portable applications. An Internal Reforming Methanol Fuel Cell (IRMFC) stack poses a highly potential technological challenge for High Temperature Polymer Electrolyte Membrane Fuel Cells (HT-PEMFCs) in portable applications. It aims at opening new scientific and engineering prospects, which may allow easier market penetration of the fuel cells. The core of innovation of IRMFC is the incorporation of a methanol reforming catalyst in the anode compartment or in between the bipolar plates of a High Temperature Polymer Electrolyte Membrane Fuel Cell (HT-PEMFC). In order to obtain an economically technologically viable solution, low-cost materials with certain functional specifications within 200-220oC (electrolytes, catalysts and bipolar plates) and production techniques, with easy maintenance and high durability will be employed. Taking advantage of the innovative outcomes of the ending FCH-JU IRAFC 245202 project, the functionality of MeOH-fuelled integrated 100 W system will be demonstrated. IRMFC partnership brings together specialists in catalysis (FORTH, UMCS, ZBT, IMM), HT polymer electrolytes (UPAT, ADVENT, FORTH), as well as the technological know-how to design, construct and test balance-of-plant components and HT-PEMFC stacks (IMM, ZBT, ENERFUEL, JRC-IET, ADVENT). Special role is adapted throughout the project for end-user/system integrators (ENERFUEL, ARPEDON) with respect to emerging portable applications. In particular Advent’s joint development with HT PEM dedicated and recognized industrial partners like Enerfuel (USA) gives the ability to adopt and integrate the advanced technolog
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Quantum Ptychography: Single-Shot High-Resolution Imaging of 1-100 nm using Coherent EUV - X-ray Light with Quantum Properties' under Horizon Europe.

assistant: **Concept**

The extreme nonlinear upconversion process of high harmonic generation produces bright, fully coherent EUV and X-ray beams at 1-100 nm wavelengths. Numerous theoretical and experimental breakthroughs have led to exquisite attosecond control of various classical and quantum properties of the light - excelling what is possible for visible and infrared lasers. However, a full understanding of the limits of the quantum nonlinear interactions in high harmonic generation is still lacking. In academia and industry, tabletop EUV technology based on high harmonic generation is already addressing grand challenges in nanomaterials science and metrology. Specifically, EUV ptychography - a lensless imaging technique - has demonstrated high-fidelity phase characterization of the high harmonic light, as well as achieved near-diffraction-limited imaging of complex systems, reaching record near-wavelength 10-20 nm spatial resolution. However, ptychography’s scanning modality and use of long-wavelength EUV light limit the tabletop high-resolution real-time applications. In this project, we address fundamental physics questions and technological challenges by performing ptychography in novel quantum regimes of X-ray generation. First, ptychography can enable reconstruction of the quantum phase of harmonics which will allow to quantify strong correlations of electrons and attosecond dynamics in multiply-charged plasmas. Experimental access to the phase space paves a way to attosecond electron correlation spectroscopy and may result in brighter X-ray generation, possibly extending the emission into the multi-keV regime. Second, using state-of-the-art EUV – X-ray sources driven by UV lasers, we aim to overcome the 10 nm resolution barrier in 2D - 3D imaging and enhance the phase contrast usi