RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'SIMULATION OF THE ASSEMBLY TOLERANCES FOR COMPOSITE AIRCRAFT STRUCTURES' under Seventh Framework.

assistant: **Concept**

One of the challenges that currently exists for the design of large aircraft structures under natural-laminar-flow (NLF) regime is the extremely high requirements that must be achieved in terms of tolerances with the aim of ensuring that the flow will be sufficiently stable. In systems composed of many parts (such as the Smart Fixed Wing Aircraft torsion box object of study), the assembly processes acquire a special relevance, taking into account that, depending on how they are executed, the tolerances of each part might accumulate and generate deviations much larger than those of the parts taken individually.The objective of the present project is the development of a numerical methodology for theanalysis of the assembly tolerances of aircraft components designed to operate under naturallaminar flow (NLF). The methodology should allow determining the maximum acceptablecomponents deviations to obtain assemblies within the specified tolerances, evaluating theinfluence of the joining techniques and the jigs, and determining the best assembly strategy orbolting sequence. For that, the proposed approach integrates tolerance accumulationtechniques and mechanical/structural tools in order to consider in the analysis the partscompliance and other possible relevant effects associated with the joints.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Regulatory roles of calcium-dependent protein kinases in the Plasmodium life cycle' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The aim of the proposed project is a characterization of a set of unique and understudied kinases that have essential functions in Apicomplexan life cycle control. These kinases, which interestingly are only found in plants and protists and not in animals or fungi, are calcium-dependent and are thought to allow for a translation of intra- or extracellular Ca2+ signals into an appropriate cellular response. The specific objectives of this proposal are (1) functional studies of two Plasmodium calcium-dependent protein kinases (CDPK1 and CDPK5) to elucidate their regulatory role in the Plasmodium life cycle, and (2) to validate these proteins as essential signaling molecules that can serve as drug targets in an attempt to effectively treat Plasmodium infection/malaria. Our proposed studies involve the construction of transgenic parasites that express epitope-tagged copies of CDPK1 and CDPK5, as well as state-of-the-art conditional knock-out and chemical genetics approaches to investigate the biological function of these proteins. In addition, a collaboration with the biophysics laboratory of Professor Jane Endicott at the University of Oxford is proposed, to produce crystallized protein for structural analysis.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Molecular control of actin network architecture and mechanics during cell shape changes' (NanoMechShape), addressing dissemination and exploitation.

assistant: **Impact**

Precise control of shape is key to cell physiology, and cell shape deregulation is at the heart of many pathologies. As cell morphology is controlled by forces, studies integrating physics with biology are required to truly understand morphogenesis. NanoMechShape will take such an interdisciplinary approach to investigate the regulation of animal cell shape.In animal cells, actin networks are the primary determinants of shape. Most cell shape changes fall into two categories: 1) those driven by contractions of the actin cortex, a thin network underlying the membrane in rounded cells; and 2) those resulting from transitions between the cortex and other actin networks, such as lamellipodia and filopodia. To understand cell deformations, it is thus essential to understand the regulation of cortex contractile tension and the mechanisms controlling transitions in actin architecture.NanoMechShape will comprise three aims. First, we will explore how cortex tension is regulated. We will focus on the role of cortex architecture, which remains elusive due to the difficulty in probing the organisation of the thin cortical network. We will unveil cortex architecture using super-resolution and electron microscopy, and systematically investigate how nanoscale architectural features affect tension. Second, we will explore how the identified regulatory mechanisms contribute to the establishment of a cortical tension gradient. We will focus on the gradient driving cytokinetic furrow ingression, an exemplar tension-driven shape change. Third, we will investigate transitions in actin architecture underlying cell spreading. We will compare spreading at the end of mitosis and during differentiation of mouse embryonic stem cells, paving the way to investigations of the crosstalk between cell
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Genome wide screening for tumour related rearrangements in mouse cancer models' (2002-2006) under Sixth Framework.

assistant: **Objectives**

Cancer in humans is typically a very heterogeneous disease and it is thus difficult to analyse genetically. One of the main thrusts of cancer research over the past 25 years has been to identify genes that are mutated in cancer. The Bradley laboratory is interested in performing one of the largest comprehensive analyses of the and 'cancer genome and in a cancer prone mouse model: irradiated bloom deficient mice. Loss of the DNA helicase Bloom function has been described in human Bloom syndrome and leads to a breakdown in the maintenance of genome integrity, in particular hyper-recombination and cancer predisposition. This gene has been knocked out in mice by the Bradley lab, and like in the human syndrome, bloom deficient mice are cancer prone in a wide variety of different cell types including carcinomas, sarcomas and lymphomas. Thus, this model provides an opportunity to identify genomic regions or genes that are frequently rearranged in cancer. The laboratory has developed an automated method to generate a genome wide molecular profile of a tumour in a single experiment using BAC-CGH arrays (comparative genomic hybridisation). Analysis of tumour DNA extracted from Bloom mouse cancer model will provide information of frequent deleted and amplified region. This study requires the analysis of hundreds of tumours and comparisons of rearrangements from tumours of the same types. Identification of sites of rearrangements will be useful in order to identify new genes involved in cancer. Once identified, these genes could be deleted in mice in order to evaluate their potential function in cancer. This will yield potential new diagnostic opportunities and perhaps might suggest new therapeutic approaches."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Multilingual and Multicultural Spaces for Political Deliberation'.

assistant: **Concept**

As highlighted by the Conference on the Future of Europe, EU citizens at large feel that the interplay between national media discourse and political/cultural contexts affects the perceptions and reactions to global events differently. Language barriers exacerbate siloed thinking, the bandwagon effect, group thinking, and the lack of diversity in dialogue around issues of international relevance, creating “areas” of thinking entrenched into national and language gates and hindering the creation of a truly European public sphere. Such challenges to democratic participation disproportionally affect members of cultural and linguistic minorities within and across EU member states. The research and innovation roadmap of the MultiPoD project aims to radically improve the political dialogue at the European level through evolving knowledge graphs and generative, Artificial Intelligence-driven technologies that mobilise collective intelligence, bridge existing communication barriers, and yield a better understanding of the interdependencies between participatory processes, policy decisions and behavioural, thought and argumentation patterns in the public deliberation of international affairs. For this purpose, MultiPoD brings together experienced use case partners, as well as European networks engaged in fostering participatory, deliberative democratic processes, technology partners with a strong track record in multilingual language processing, and leading research partners, specialised in collective intelligence, argumentation theory, human-computer interaction and visual methods for supporting and analysing online communication.


**Keywords:** Hybrid Citizen Deliberation, Deliberative Democracy, Multilingual Political Dialogue, Cross-cultural Argumentation, Automated Knowled
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Elaboration of hydromechanical coupled models by interpretation of the disturbances observed during the sinking of the main shaft of an underground laboratory in eastern France'.

assistant: **Objectives**

An instrument array will record the rock mass response during shaft sinking for an underground research laboratory in Eastern France in a deep argillite formation. This kind of geological formation is considered as a potential host rock for a radioactive waste repository. The proposed MODEX-REP project consists in: development of the constitutive models by analysing surface laboratory tests results; prediction of the rock mass response to shaft excavation; analysis of the results of in-situ measurements; comparison of the prediction with the measured rock mass response; and validation of the models. The relevance of the constitutive models for predicting rock mass hydromechanical behaviour will be evaluated through the comparison. The models validated by in-situ testing at natural scale will enhance public confidence in prediction capacity. Shaft excavation is not included financially in the proposed project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Nanostructured Toughened Hybrid Nanocomposites for High Performance Applications'.

assistant: **Objectives**

Motivation: Nanocomposites are emerging new materials that promise improved properties. Their applicability, however, is presently limited by the cost of manufacture and product reproducibility. Literature shows that on the bench scale, dramatic improvement in polyolefin mechanical properties can be obtained by intercalation and exfoliation of nanoparticles in the matrix. However, when materials produced using conventional equipment are tested, their performance does not meet expectations nor live up to the claims (eg. the impact strength too low).    Project Goals: To remove technical barriers to producing high performance polymer nanocomposites on the industrial scale, fundamental insight into the dispersion of particles within the matrix is needed. The goal of this project is to gain this insight through a series of carefully designed studies, using the most advanced experimental techniques, theoretical modeling, carried out by very experienced and skilled partners working together in a targeted and interdisciplinary fashion.    The basic objective is to obtain a deeper understanding of the interfacial structure of nanocomposites within a polyolefin matrix. This knowledge will enable realization of the great performance potential of these materials through development of novel multiphase and hybrid nanocomposites. This knowledge will facilitate commercialization of polymer nanocomposite materials with superior properties that will lead to development of new products. To meet this objective, we aim to improve the stiffness of polyolefin nanocomposites while not only maintaining but also improving the toughness of the matrix considerably.    The technological objective is to optimize and, through novel interface design, to develop new cost efficient hybrid (nanofiller–
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Versatile mass and rheological sensing platform' in the context of a Horizon 2020 call.

assistant: **Objectives**

The MARS project will develop a platform for measuring mass at microscale and rheological properties of Newtonian/ non-Newtonian fluids in real-time, with unprecedented resolution, accuracy and reliability. This will be achieved by exploiting some unique degrees of flexibility in the dynamical response of a self-excited micromechanical probe. Depending on the desired application, this platform can be either used as a continuous sensor, a threshold sensor or a stable reference. Measuring the mass of analytes with high accuracy and understanding the rheology of simple and complex fluids play a critical role in a wide variety of applications in the ever-growing smart sensor global market.The success of the MARS project requires:- Advanced modelling of the dynamical response of self-excited microresonators oscillating in Newtonian or non-Newtonian fluids while subject to mass changes;- Design, development and optimisation of the new sensing platform;- Real case experiments for mass sensing, to assess and showcase the capabilities of each sensing modality;- Characterisation of the properties of weakly non-Newtonian viscoelastic fluids.This platform addresses several of the main drawbacks of current techniques to measure mass or to characterise viscoelastic fluids and presents some unique features: i) Self-sustained oscillations that keep track of any environmental changes affecting the mechanical probe, without requiring any external equipment; ii) Possibility of controlling a variety of sensing modalities by introducing delay in the feedback loop with a phase-shifter circuit; iii) Capability of sensing extremely small mass (potentially single molecules) and weakly non-Newtonian fluids.The end technical result will be a proof-of-concept prototype to demonstrate the effective
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Foundation and justification of values in Aristotle's ethics' under Sixth Framework.

assistant: **Concept**

Aristotle is often criticized for not having treated the question, essential in modern philosophy, of the foundation and justification of values that correspond to what Aristotle calls the virtues. It is true that one doesn't find any explicit and developed treatment of this question in Aristotle's work. But are three main areas where we can reconstruct the Aristotelian response to that question: the theme of the happiness as the end of virtues; the theme of the person of practical wisdom presented as the measure of the mean which constitutes each virtue; the theme of the method of Aristotle's s ethics which is a dialectical one. Hese themes will be studied by linking them to contemporary philosophical approaches.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The sustainability indicator framework to communicate responsible aquafood production and consumption patterns' (VeriFish) targeting Horizon Europe.

assistant: **Abstract**

Citizens’ decisions are central to living within the limits of our planet. Purchasing choices can drive change at retail and raw commodity levels but the complexity of fish and seafood food chains, health benefits and risks, and climate impacts need to be simplified and made more accessible and readily comparable. Currently, there are no standardised ways to inform citizens about the various health issues, nor are there guidelines or harmonised indicators for sustainable European fish and seafood products. VeriFish will offer a framework of verifiable sustainability indicators for communications about sustainability based on FAIR data from EU- and global aquafoods repositories, brought together through the extraordinary collaboration of European-wide actors like NOFIMA, EUROFIR and POSEIDON. Leveraging on this indicator, VeriFish will design, develop, and disseminate a number of media products  to help citizens, seafood consumers and retailers, associations and policy makers make informed consumption choices. NOFIMA domain experts will work with renowned scientific communicators from EuroFISH and experienced community builder Trust-IT publish a good practice recommendation framework on neutral indicators to communicate sustainability along different consumer segments, aquafood retailers, seafood and aquaculture producers and associations, as well as guidelines for their use in retail and HoReCa (hotels, restaurants, catering).  A prototype web application will digest indicators into an accessible (easy to use) comprehensive media product for user communities,  including citizens, summarising nutrition, sustainability, and biodiversity aspects.  The framework will be open access, and will be tested via a series of related end-user engagement campaigns targeting younger g
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Access to belgian collections of interest for biodiversity research' (ABC) under Fifth Framework.

assistant: **Objectives**

The ABC scheme offers to 120 European researchers, scientific expertise, technical assistance and financial support to access one of the 3 most important zoological collections of the EU. Covering all animals groups and enriched by many databases and a huge biology library, these collections offer, with advanced technical facilities such as DNA-lab or electronic microscopes, a unique opportunity to study some of the references needed in many biodiversity researches. ABC scheme will hereby contribute to reinforce the European potential for biodiversity research and, by facilitating access to new users, will contribute to sustain systematics and taxonomy, the two fundamental biology sciences. By reinforcing the EU audience to Belgian patrimony, ABC project contributes to the sharing of scare resources at EU level. ABC scheme will lead to many publications which are useful for a better understanding of biodiversity, evolution, phylogeny and more globally ecosystem functioning.Application:Applicants must fill in a form available on the RBINS website and particularly take care to the presentation of their scientific project, their outcomes expected and the object of their visit to RBINS. All eligible application forms are evaluated by a Users Selection Panel composed of taxonomists and scientists covering all RBINS field of research.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Modular beads for regeneration of bio-cofactors in enzyme-catalysed synthesis' (HydRegen), addressing dissemination and exploitation.

assistant: **Impact**

There is increasing interest in exploiting enzymes to carry out steps in industrial catalysis. Biocatalysts permit reactions to be carried out under mild conditions and with the exquisite chiral and regio-selectivity demanded of pharmaceutical, food and fine chemical products. A growing number of enzymes are already utilised across these industries. However, the repertoire of enzymes available for industrial redox transformations is greatly limited by the requirement of many oxidoreductase enzymes for supply of the hydride-carrying nicotinamide adenine dinucleotide (NAD) cofactors at stoichiometric levels. The high cost of these cofactors means that a regeneration system is essential. In this project, we develop towards commercial application, a convenient, cheap, modular regeneration system for the nicotinamide cofactors NAD+/NADH and NADP+/NADPH. Our innovation is likely to have broad applications in facilitating enzyme-catalysed steps in the preparation of pharmaceuticals and other fine chemicals, and to offer substantial advantages over currently available cofactor recycling systems. This project builds on ideas and early-stage results that have arisen rapidly out of an ERC Starting Grant-funded project. We now apply for funds to protect our Intellectual Property, explore the surrounding market and patent landscape, and develop our innovation into a robust demonstration.