RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Respirable Advanced Therapeutics for Cystic Fibrosis & other Lung Diseases' (ReSpire).

assistant: **Innovation**

Via the SME Instrument OmniSpirant Ltd will mature its stem cell exosome-packaged gene therapy with lung mucuspenetration properties which will be more effective (improved lung function, reversal of lung damage and superior CFTRgene expression and function) and also be applicable to 100% of the CF global population. This approach, using a combinedpatent pending exosome surface engineering for enhanced mucus penetration and cell transfection with a tailored vibratingmesh nebulisation aerosol delivery method will provide a unique, potentially disruptive, therapeutic modality for CF and manyother lung diseases with high unmet medical need.Our competitive advantage and Unique Selling Points lower current effectiveness barriers and make the OmniSpirantexosome technology the only therapeutic delivery method that could provide a truly effective treatment for CF, thusimproving both survival rates the quality of life of CF suffers. Importantly, the quality of life for CF patients will increase topoint where they are able to work. The OmniSpirant system will, over time, be regarded as an essential weapon in thearmoury of health systems in the battle against other serious respiratory conditions affecting major patient populations suchas lung cancer and COPD, globally.The overall objective of our feasibility study is to demonstrate the potential value of the combined gene therapy systemmaturation based on a comprehensive analysis of the business concept in terms of technical, commercial and financialviability. The outcome of the study will be a full Business Plan that will feed into a Phase 2 project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Methodology Development towards a Label for Environmental, Social and Economic Buildings' (LENSE) under Sixth Framework.

assistant: **Objectives**

LEnSE is a research project that responds to the growing need in Europe for assessing a building's sustainability performance. The project draws on the existing knowledge available in Europe on building assessment methodologies. LEnSE aims to develop a truly holistic methodology that addresses the overall, integrating concept of sustainability. The main objective of LEnSE is to develop a methodology for the assessment of the sustainability performance of existing, new and renovated buildings, which is broadly accepted by the European stakeholders involved in sustainable construction. This methodology will allow for future labelling of buildings, in analogy with the Energy Performance Directive. The work should result in increased awareness of the European stakeholders and will allow adequate policy implementation on sustainable construction. The project consists of three main themes. The first theme is the identification and scope of the issues which need to be included in a sustainability assessment. This has to be wide enough to be acceptable and limited enough to be practicable. A broad consensus on these issues will be reached through strategic consultation of the relevant stakeholders. The second theme is the actual development of the assessment methodology. The content of the assessment will be developed for a limited, but representative range of key issues. Guidelines on how to address local variations will be provided. This work will be validated by the development of a prototype tool and tested on case study buildings. The key stakeholders on the European and national level will be highly involved in the development of the methodology, to guarantee a wide acceptance and implementation of the project results. These consultations will include national meetings wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Becoming Muslim: Conversion to Islam and Islamisation in Eastern Ethiopia' in the context of a Horizon 2020 call.

assistant: **Objectives**

Why do people convert to Islam? The contemporary relevance of this question is immediately apparent.""Becoming Muslim"" will transform our knowledge about Islamisation processes and contexts through archaeological research in Harar, Eastern Ethiopia, and examine this in comparison to other regions in sub-Saharan Africa via publication and a major conference. Assessing genuine belief is difficult, but the impact of trade, Saints, Sufis and Holy men, proselytisation, benefits gained from Arabic literacy and administration systems, enhanced power, prestige, warfare, and belonging to the larger Muslim community have all been suggested. Equally significant is the context of conversion. Why were certain sub-Saharan African cities key points for conversion to Islam, e.g. Gao and Timbuktu in the Western Sahel, and Harar in Ethiopia? Archaeological engagement with Islamisation processes and contexts of conversion in Africa is variable, and in parts of the continent research is static. This exciting 4-year project explores, for the first time, Islamic conversion and Islamisation through focusing on Harar, the most important living Islamic centre in the Horn of Africa, and its surrounding region.Islamic archaeology has been neglected in Ethiopia, and is wholly non-existent in Harar. Excavation at 5 key sites: 2 shrines, 2 abandoned settlements, 1 urban site, will permit evaluation of urban Islam, the veneration of saints, pilgrimage and shrine based practices, rural Islam, architecture and jihad, changes in lifeways, and early and comparative evidence for Islam and long-distance trade, through analysis of, e.g. architecture, epigraphy, burial orientation, imported artifacts, and faunal and botanical remains. Although it is fully acknowledged that conversion to Islam and Islamisati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'CoPIRL: Compact High Power Picosecond Infrared Laser for Scar Free Surgery and Bio-Diagnostics.' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The PIRL concept is the first method of any to achieve surgery without scar tissue formation. This new laser concept has achieved the long held promise for the laser for attaining the fundamental limit to minimally invasive surgery.  The very prospect of high precision surgery without scar tissue formation is readily appreciated to potentially revolutionize surgery and holds equally great promise in providing in situ bio-diagnostics.The goal of this work is to develop a more compact and higher power version of the ERC SUREPIRL (ERC AdG_20110209, project ID 291630) project’s laser system with improved beam quality and delivery methods to drive adoption of the concept and open up commercial surgical and bio-diagnostic applications.  The current cross-disciplinary collaboration between the physicists, chemists, and surgeons within the SUREPIRL project has led to significant advancements in knowledge as to demands on beam power and beam shape necessary for full scale commercial implementation of this technology. This proposal builds upon the unique applications enabled by the novel PIRL technology – currently under investigation by the SUREPIRL project – to develop a new laser device based on direct amplification of 3 µm laser radiation. Recent advances in the field of research on Chromium-doped chalcogenide gain materials make it possible to realize sufficient power amplification in this wavelength region on the picosecond pulse timescale. This potential gain in power and reduction in size will permit for the rapid translation of SUREPIRL project findings to industry, with significant commercial and societal benefit.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Human gut Microbiome, gene Expression and Colorectal Cancer: Assigning causal roles from a novel Mendelian randomization perspective.' (MECoCaM), addressing dissemination and exploitation.

assistant: **Impact**

The contribution of the gut microbial ecosystem to colorectal cancer (CRC) is not well understood. Inflammatory processes and unbalance cell proliferation in the host could be behind observed correlations between a microbe and cancer stages. However, the enrichment of a microbe at a tumour site does not directly assume causation. Rather, this could be the result of a reverse causation or a confounding third factor. Therefore, two major challenges unravelling CRC aetiology are (i) to identify the mechanistic interactions of microbial communities with host intestinal epithelium cells, and (ii) to assign causality to carcinogenesis. These are the aims of this project integrating different “omic” data, and using a Mendelian randomization (MR) approach.In this study we analyse microbiome sequencing data, from up to 500 normal colon mucosa biopsies, to provide a comprehensive description of the gut microbiome. Additionally, we integrate transcriptomic data from these well phenotyped 500 samples to understand the interaction between microbes and the gut epithelial cells. Finally, using the germ-line genetic variation of host cells as a third “omic” layer, the correlations between microbes and (i) environmental exposures, (ii) gene expression, and (iii) CRC can be validated by MR. MR is an analytical approach whereby germ-line genetic markers are used as proxies – or instrumental variables – for putative risk factors. These genetic markers cannot be influenced by reverse causation, and, assuming an absence of pleiotropy, can provide unconfounded estimates of association. Therefore, a MR association between genetic proxies and the outcome of interest would indicate that the exposure being proxied is associated in a causal manner.The identification of the functional relevance and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Environmental friendly and Durable Oil and water repellence finish on Technical Textiles'.

assistant: **Concept**

In the current market, the well-known brands of technical textiles are coated with Perfluorocarbon chemistry to possess highly durable oil and water repellent (OWR) finish. In early days, water repellent finish for fabrics was provided by simple paraffin or wax coatings which washed out eventually. Alternatively, PFOS and PFOA are the chemicals belonging to the family of perflourochemicals (PFCs) also known as C8 chemistry is used. Although PFC-C8 are used together with binders that act as glue to stick to the surface of fabrics, as it is not chemically bonded to the substrate it leaches out, causing ecological threat. Recent studies have found PFC-C8 present in the blood, tissues and foetal-cords of human and its bio-persistence and bioaccumulation in the environment has caused significant concerns. Notably, due to these concerns, 3M withdrew Scotchguard from the market in 2000. C8 Fluorocarbons are currently under high regulatory pressure (2006/122/EC) and it’s outlawed in favour of C6 chemistry which performs lower to meet the industries durability and repellence standards.There is a strong demand for replacing the C8 chemistry with an equally performing finishing chemical. TEX-SHIELD will develop a novel, multifunctional molecular structure with silica backbone that is chemically bondable to the fibre/filament to achieve a highly durable textile finish that is resistant against the oil/grease /powder stains by biological route. The reasonable silica content in it will replace the C8 chemistry while providing equal performance. A replica of film forming effect will be formulated.  The project will evaluate the suitable deposition technique. TEX-SHIELD will provide the textile industry with a cost effective and environmentally safe OWR finish on textiles, revolutionis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'An economic analysis of the rise in obesity' under Sixth Framework.

assistant: **Concept**

The proposed research aims at understanding the causes of obesity, addressing the problem from different angles, with an interdisciplinary perspective, involving both social epidemiology and economics.The research will address the effects of obesity on economic behaviour. It will work out differences across countries in the association of obesity with socioeconomic characteristics. It will address how obesity in children and adolescents relates to parental characteristics and context, as well as medical conditions early on in the life of children. It will analyse how individual obesity is related to obesity in peer groups.Research will be mostly empirical, and exploit information in large survey data sets of different types. To accomplish the project, Ms Cornaglia will spend two years in the Department of Economics at UCL. This is a leading institution for Applied Economics and Econometrics in Europe. The department and its associated research centres do not only provide the expertise, but also the facilities and infrastructure to conduct top academic research of this kind.The project will give an important stimulus to Ms Cornaglia's academic career. She will be able to draw on the unique expertise at UCL on the various aspects important for her project, build strategic links, and launch joint projects with other researchers. The existing links between the departments of economic and epidemiology, facilitated by her advisor Dr Adda who has a joint appointment, are important for research of the type suggested.The current project may also have beneficial spill-overs towards the creation of scientific links between UCL and Ms Cornaglia's home university, the University of Turin, to which Ms Cornaglia intend to return at the end of the project, thus contributing to the regi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Securing a healthy indoor air climate while saving energy in buildings with space technology' under Horizon 2020.

assistant: **Concept**

90% exposure to air pollution does occur indoors, causing almost 70% of the total burden of disease related to indoor air quality. With 90% of European citizens spending 90% time indoors, good environment inside buildings is a key public health issue, costing €1,273 B each year. Overall, air treatment is responsible for 40% of total building energy consumption, and ventilation-related operations represent alone up to 26% of the electricity expenses. This is because current ventilation approaches consume huge amounts of energy by replacing indoor air with air from polluted outdoor environment. Thus, they need to choose between air quality and energy savings, so the better indoor air quality they achieve, the more energy spending, and the opposite way around. SALLY_R is a Swedish cleantech SME that has been awarded twice already for its disrupting innovation, s8AIR, an Air Handling Optimization System that guarantees optimum indoor air quality spending 40% less energy. For an average office building area of 870m, S8AIR‘s energy savings (0.3 kWh/m2/day) would lead to less 63.5 MWh/year energy consumed, amounting for €12,970/year. s8AIR combines ventilation approaches used on Earth with the actual technology for climate control in the International Space Station to enhance the performance of air handing units no matter capacity. This is achieved thanks to our own developed smart algorithm that intelligently exploits the real-time data acquired from several sensors. Our novel system can be integrated either into existing Air Handing Units in building refurbishment/renovation operations or into new units, so after having demonstrated our product capabilities through the easy deployment in refurbished buildings, we will target AHU manufacturers to integrate S8AIR into their we
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Pilot line production of functionalized CNTs as thermal interface material for heat dissipation in electronics applications' (SMARTHERM), addressing dissemination and exploitation.

assistant: **Impact**

The global economy is benefiting from the fast evolution of the semiconductor industry. The primary driving force of the semiconductor industry is the increasing integration density, which has lead not only to higher transistor density but also to increasing power density. Power density is expected to increase up to 135 W/cm2 in 2024 for single chip packages. This puts significant stress on thermal management technology. Obviously, there is a need for improved thermal management within the field, and innovative TIMs constitutes a key component in reaching this goal. TIMs with dispersion of CNTs in polymer matrices for improved thermal conductivity have been reported. However, the thermal conductivity in these composites is insufficient and fundamental limitations stem from the huge interfacial contact resistance between the CNTs and the contact resistance between the CNT ends and target surfaces. Therefore, SMARTHERM project is initiated aiming to build up a pilot production line for high-performance TIMs based on functionalized CNTs. The utilization of vertically aligned CNT structure eliminated the CNT-CNT contacts along the heat transfer path and the functionalization at the CNT ends dramatically decreased the contact resistance. The main outcomes of the SMARTHERM project are two types of CNT based TIMs manufactured in a roll-to-roll manner which allows large scale production at industrial level. The TIMs will be demonstrated by two demonstrators proposed by TRT. The consortium consists of 5 partners from 3 European countries and integrates competence from 2 big companies, 2 SMEs and 1 university. TRT and SHT have been funded by the FP7 framework programme NANOPACK and SMARTPOWER, in which SHT and TRT have obtained great amount of knowledge on CNT based TIMs. Therefo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Software Components for Robust Geometry Processing' (TITANIUM).

assistant: **Concept**

The TITANIUM proposal aims to develop a software demonstrator for geometry processing and 3D urban modeling, in order to facilitate the pre-commercialization of novel software components for the Computational Geometry Algorithms Library. The proposed demonstrator will include novel approaches resulting from the ERC-funded IRON project (‘Robust Geometry Processing’, StG-2010-257474), which are illustrated by publications presented at premier conferences in our field (receiving two best paper awards) and a patent submitted in 2015. The expected outcomes of TITANIUM will be versatile methods for 3D reconstruction and simplification of data gathered from geometric measurements, as well as related methods specifically tailored to urban modeling. These methods represent a significant step forward by offering unrivaled levels of robustness, and automated generation of levels of detail that are semantically meaningful. The acronym TITANIUM, a robust and lightweight material, conveys our wish to streamline the geometric modeling pipeline through robust algorithms and lightweight representations. This Proof of Concept project will also implement the steps required for pre-commercialization. In view of this goal, we have included an industrial partner, GeometryFactory, a spinoff from Inria launched in 2003. We have already established preliminary contacts in the fields of metrology and geographic information systems. These contacts will provide real-world industrial case studies.