RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Network of National Contact Points for Cluster 6: Food, Bioeconomy, Natural Resources, Agriculture and Environment'.

assistant: **Objectives**

CARE4BIO serves the needs for transnational cooperation between NCPs for Cluster 6 as well as for cross-cluster cooperation within Pillar 2, but also with other programme parts such as Widening Participation. We comprise a well-balanced network of 26 partners, including partners from the EU-13 and Associated Countries, combing all levels of relevant experience and expertise. Many of us fulfil multiple roles, for instance also working in NCP_WIDERA.NET, NCP Academy or EEN, different clusters and pillars, or appointed as programme coordinators.We are well set-up to deliver on our objectives, namely to (1) harmonise NCP services and increase their quality via transnational cooperation, (2) lower entry barriers for applicants, especially in less active member states and raise the quality of submitted proposals, (3) inform the European R&D community about cross-cutting synergies throughout Horizon Europe.To achieve this, we will cooperate with other (NCP) networks such as the ones mentioned above, to share knowledge and best practices, maximise efforts on informing NCPs, applicants and stakeholders, thereby raising the quality of proposals, breaking down silos, and encouraging trans-cluster collaboration. We will cooperate with the European Commission to assist in delivering upon political objectives such as the EU Green Deal, guiding applicants on policies, and providing feedback from our work as NCPs. We also offer concrete services for applicants, e.g., by organising yearly brokerage events to aid applicants in forming their own cooperation networks, and by supporting other matchmaking efforts.Our services will include training, learning resources, best practice manuals, policy briefings, and more. While our services will be available to whoever needs them, our focus is o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Epitranscriptomics at the crossroads of metabolism and cellular ageing' (EpiMetAgeing) under Horizon 2020.

assistant: **Objectives**

Ageing is an unavoidable consequence of living and constitutes the highest risk factor for most human diseases in modern “western” societies. Despise the frequently observed correlation between metabolic alterations and cellular ageing, the molecular mechanisms linking these two complex processes are far from being understood. Here the EpiMetAgeing project proposes to take a novel approach to investigate cell decline linked to obesity and ageing through the lenses of RNA modifications, specifically TET2-mediated 5-hydroxymethylation of cytosines (5hmC). For that purpose, we will characterize the impact of obesity throughout ageing in: (1) the distribution and dynamics of 5hmC epitranscriptomic modification and (2) the key RNA-binding proteins that mediate TET2 function. Given that RNA modifications are reversible, the ultimate goal of this project is to develop novel strategies for cellular rejuvenation. To this end the ER will use cutting-edge technologies, including next-generation sequencing techniques, proteomics, CRISPR activation and repression systems, metabolic phenotyping and iPSC technology. EpiMetAgeing will provide a deeper understanding of the implication of a specific RNA chemical modification in orchestrating metabolism and ageing. Our research has the potential to facilitate the identification of potential druggable targets for therapeutic intervention in age-associated metabolic diseases.EpiMetAgeing has been carefully designed by combining the ER and host expertise in a highly interdisciplinary research environment to boost her career opportunities, and enhance her possibilities to achieve a position of greater professional maturity and independence that will allow her transition to become a principal investigator in the European R&D system.


**Keywor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Interdisciplinary and Intersectoral Research Fellowship Program for Future Leaders in Immunology'.

assistant: **Concept**

Interdisciplinary and Intersectoral Research Fellowship Program for Future Leaders in Immunology (IMMUFELLOW) is an innovative postdoctoral training initiative of the University of Turku (UTU) and Åbo Akademi University (ÅAU) in Turku, Finland. Immune-related diseases, such as infections, atherosclerosis, and cancer, are increasing in prevalence and pose major societal/economic challenges. IMMUFELLOW will cultivate experts and leaders in immunology who will drive research advancements to address unmet needs in preventing and treating immune-mediated diseases. IMMUFELLOW will build on UTU’s/ÅAU’s excellence in leadership development, advanced education models, and beyond state-of-the-art immunological research ecosystem and infrastructure. With 22 experienced postdoctoral researchers (ERs) recruited for 36-month terms via a rigorous, merit-based selection process, this initiative prioritizes interdisciplinary and intersectoral research, aligning with the European Charter and Code. Supported by the InFLAMES Flagship, IMMUFELLOW fills a critical void in postdoctoral training, offering a structured program integrating science, technology and entrepreneurship. IMMUFELLOW ensures comprehensive research excellence and training opportunities beyond academia, with the following key features:Support and Mentoring: Each ER benefits from a dedicated intersectoral mentoring team, access to exceptional training opportunities, and monthly seminars/networking events.Sector-Wide Involvement: Beyond academia, fellows explore research, training, and development opportunities in corporate settings, with education on regulatory standards/good practices in diagnostics, drug development, and manufacturing.Entrepreneurial Skills: Equipping fellows with the skills and knowledge to thrive in div
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Insight inside: signal transducing protein machines revealed by subcellular single molecule spectroscopy and imaging (INSIGHT INSIDE)' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

The molecular basis of programmed cell death (PCD ) , a system common to both plants and animals, will be studied to learn more about signal transduction cascades. PCD is a process of cell suicide critical for development and tissue homeostasis of multicellular organisms. It requires sophisticated signal transduction machinery, controlled by an evolutionary conserved program. Understanding PCD is important for drug discovery in human medicine and pathogen resistance in agriculture. Shared features of plant and animal PCD will be used to deduce the primordial components of eukaryotic PCD To increase our understanding in this field, micro spectroscopic techniques will be used because they provide quantitative information on molecular interactions and dynamic events involving signalling molecules (SMD) , they can be used as high throughput methods and combined with other advanced imaging methods.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'PV FINANCING' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Feed-in tariffs (FITs) have been the fuel for successful solar PV growth stories in basically every one of today’s large solar markets. First in Europe, now in China and Japan. The US is the only exception – backed by tax credits and net-metering, leasing has become a key means of financing residential solar systems there.With many European countries phasing out FITs, the simplicity of selling solar power will be gone; and without safe and fair returns, real estate and homeowners will not invest in PV anymore. In post-FIT times, solar companies and/or electric utilities in partnership with financial institutions will have to come up with new business models and financing schemes for PV investors in order to continue the success story of the FIT era. The German Solar Industry Association as project coordinator is driven by the mission to successfully evolve those business and financing models, to disseminate them among stakeholders and to shape the necessary policy framework and to remove barriers that prevent those models from realization. Consequently, the goal of PV Financing is to help stakeholders from specific application segments with the implementation of PV projects based on new PV business models while applying innovative equity and debt financing schemes. The availability of financing for PV projects based on the new business models shall be increased and the transaction costs shall be decreased by educating investors, commercial banks and insurance companies on the PV business models and their risks.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Sleep on Command: a breakthrough technology for sleep, pain relief, enhanced performance and        regenerative health.' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Approximately 30% of the population have difficulty initiating and maintaining sleep. This proportion is continually increasing due to growing geriatric populations and various modern lifestyle habits such as frequent use of stimulants and longer working hours. Existing solutions such as sleeping pills, cognitive behavioural therapy and sleep devices are costly, time-consuming and have poor efficacy. Sleeping pills can also cause dependency issues among other adverse health effects. Currently, there is no solution that is effective for the most extreme cases of insomnia associated with chronic pain and severe post-traumatic stress disorder. Sana Sleep is a cost-effective and prescription-free sleep aid that enables users to fall asleep quickly, easily and safely on command. The device can uniquely be applied as a tool for pain relief, enhanced performance (in our tests we found military fine motor skills improved by 20% and speed driving times in the special air force increased in 19/20 trials) and regenerative health (the device can help treat concussion, stroke and traumatic brain injuries). The device is a wearable mask that puts users to sleep via tailored light and sound pulses in a unique pattern coupled with real-time, heart rate variability biofeedback. Users save significant time, hassle and potentially thousands of euro using this portable device while also gaining life-changing health benefits. The most hard-core sufferers of insomnia that have associated chronic pain and/or stress will be able to find relief for the first time by using the device to put themselves to sleep in 8-10 minutes. Its comfortable design and multi-mode capability (sleep, meditation and nap modes available) are additional benefits of using Sana Sleep.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'A quantitative, multifunctional, non-invasive and cost-effective food freshness indicator to reduce food waste', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Every year more than one 1.3 billion tons of food are wasted which is a huge both environmental and economic problem. Food waste happens all along the pathway to the plate and is a massive food supply chain inefficiency. For example inefficiencies occur when the fresh food manufacturers perform destructive quality controls every hour to detect leaks in the packaging, or when the cold chain breaks occur during transit, or when consumer fights against uncertainty by throwing away food. The expiry date is fixed during the packaging through studies of life-time and causes all agents in the food supply chain to lose money and waste resources at some point. Currently, the traceability tools available in the market do not offer information on the real state of freshness and quality of food products. ColorSensing is based on an advanced algorithm able to correct color distorsions of QR codes made of smart inks for sensing parameters inside food packages. Integrating this with digital solutions allows to monitor the freshness of packaged foods and extend their shelf life. Our innovative technology (TRL6) is a quantitative, multifunctional, cost-effective and non-invasive food freshness indicator to reduce food waste. We have received public funds to develop our technology (e.g. €1.5m from the EU ERC program) and been selected to participate in multiple startups accelerator programs such as ENPENTA VII or Innofood. We have created an ecosystem of industrial partners (food manufacturers as Embutits Monells, Barrufet Group and supermarkets as Bonpreu and Condis) that are interested in our technology and are asking us to develop our prototypes up to a market-ready solution. We aim to become the next quality standard in packaged food manufacturing and now we are applying to the SME I
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Testosterone threshold required for spermatogenesis' under Seventh Framework.

assistant: **Concept**

Follicle-stimulating hormone and high intratesticular (IT) testosterone (T) level are required for qualitatively normal spermatogenesis. Treatment with T has been successfully tested in male contraception, because it can abolish gonadotrophin secretion through enhanced negative feedback action and arrest spermatogenesis. However, none of the T treatment regimens tested have resulted in complete azoospermia in all men, for reasons not yet understood. After complete T induced suppression of gonadotrophins, the residual ITT levels are 2% of normal, yet similar to those in peripheral circulation. The residual constitutively produced ITT could be the reason for the suboptimal contraceptive efficacy.       The purpose of this study is to address in details the dependence of spermatogenesis and its suppression during contraceptive treatments on ITT level. The particular aim of this proposal will be to demonstrate in experimental conditions (mice) that the necessary peripheral androgen actions and spermatogenic arrest can be achieved simultaneously, which is fundamental for the functionality of an androgen based male hormonal contraceptive. The project will be articulated on three major objectives: (i) to determine the threshold of T replacement dose that maintains peripheral androgen actions without stimulating spermatogenesis; (ii) to design a way to suppress ITT production below the level achieved by gonadotrophin blockage, and (iii) to design a way to increase the efficacy and safety margin of T replacement dose by blockage of the constitutive T production. We expect that these experimental studies will show that it is important to eliminate the gonadotrophin independent component of ITT to maximise the efficacy of male hormonal contraception.      In addition, this project
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'SUPERCONDUCTIVITY - FERROMAGNETISM INTERPLAY in NANOSTRUCTURED HYBRID SYSTEMS' to be submitted under Sixth Framework.

assistant: **Abstract**

We propose to launch an exhaustive investigation of hybrid Nan structures incorporating super conducting (S) and ferromagnetic (F) metal components. We will investigate experimentally and theoretically fundamental quantum electronic and magnetic phenomena occurring in superconductor and ferromagnetic-based hybrids, dynamic and kinetic transport effects, the processes of spin filtering and spin injection, and the possibility of coherent manipulation of an individual electron spin. In the course of this work, we shall master the metal-ferromagnetic interface technology, and develop techniques for manufacturing micron and sub micron-size circuits. The exciting new feature of S-F hybrid structures consists of the competition between ferromagnetism and superconductivity, representing two antitheses in condensed matter physics, which is of abiding interest in fundamental and applied materials science and occurs naturally only in few exotic materials. Now we aim to produce it artificially in structured-structured composite materials, such as S-films with embedded magnetic clusters-clusters, in S-F-S and F-S-F multi-layers, and in sub-micron size hybrid circuits. The mutual proximity between superconductivity and ferromagnetism, possible as these are brought together within a nanometre scale, will create new quality with not yet known quantum ground state and kinetic properties. In the long term, new emergent quantum and macroscopic phenomena will be found that are not observed in bulk materials, only in such artificial structures. Understanding of the physics involved will be combined with the search for novel guiding principles for the next generation magnetic memory and, in the long term, enhancing the material and device functionalities via combining the specific properties
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'QUAdrupoleCOrrector', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The full exploitation of the Large Hadron Collider (LHC) is the highest priority of the European Strategy for particle physics. Because of this accelerator Europe is in a leading global position on High Energy Physics research. To preserve that position, the LHC will need a major upgrade in the 2020s to increase its luminosity by a factor of five beyond its design value. The novel configuration, known as High Luminosity LHC, is based on the development of key innovative technologies representing exceptional technological challenges.The LHC now has an urgent need for magnet technologies at the cutting edge of science which are currently not on the market and are not even being considered by commercial suppliers due to their novelty and low volume production demands. The requirements of the LHC are, among others, “long orbit corrector magnets” for the necessary adjustment of the particles orbit and “two-in-one quadrupoles magnets” in charge of providing the strong focusing of particle beams. To the companies that should produce these magnets, the commercial application potential for this technology is – at this time - too low. The QUACO project draws together several research infrastructures with similar technical requirements in magnet development, which will allow the avoidance of unnecessary duplication of design effort and reduce overall cost through economies of scale using a joint procurement process. By pooling efforts on technological requirements and using their experience from prior procurements, the partners in QUACO will act as a single buyer group with sufficient momentum for potential suppliers to consider the phased development of the requested magnets. The pre-competitive procurement (PCP) instrument used in this project will thus take away the mismatch be