RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Towards an efficient mobile Internet' (MOBILENET), addressing dissemination and exploitation.

assistant: **Impact**

It is expected that, very soon, the Internet will connect billions of mobile device users. This places high demands on the communications infrastructure and on the mobile devices. Specifically, future networks should support heterogeneous wired and wireless network technologies, be dynamic yet robust, offer high data rates, and use resources (such as bandwidth or energy) as efficiently as possible. Future mobile devices should be small and have low energy-consumption while offering high functionality.To explore how to use the resources in future communication networks in the most efficient way, I will derive information-theoretic limits of communication networks and suggest communication strategies that attain those limits. Such limits have been studied extensively in the past. However, the majority of the work has made simplifying assumptions, such as that the nodes are perfectly synchronized, have perfect channel state information, or use infinitely long codewords, which are not realistic for wireless and dynamic networks. In this project, I will derive realistic fundamental limits by including asynchronism, noncoherence, and latency constraints in my analysis. I will then propose communication strategies that attain these fundamental limits.A related topic addressed in this project is the design of mobile devices. Using tools from information theory, I will study the fundamental tradeoff between performance, robustness against nonlinearities in the devices, and implementation complexity, aiming at novel encoding and decoding algorithms that can be implemented efficiently in hardware.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'OPTIMALITY PRINCIPLES IN RESPONSES TO ANTIBIOTICS' in the context of a Seventh Framework call.

assistant: **Objectives**

Antibiotics kill bacteria or inhibit their growth by targeting essential cellular processes. In response to antibiotic exposure, bacteria activate gene regulation programs that are specific to the action of the antibiotic. These responses to individual antibiotics are often well-mapped, but how do bacteria respond dynamically to drugs? And is this regulation optimized for survival and growth in the presence of the drugs?We propose an interdisciplinary experimental-theoretical approach to measure, model, and synthetically manipulate the regulatory response to antibiotics. Specifically, we will (1) use an automated robotic system, an Escherichia coli library of fluorescent transcriptional reporters, and RNA-seq to measure changes in growth, physiology, and global gene expression in response to antibiotics; (2) develop theoretical models of gene regulation and predict ‘re-wirings’ of the gene regulation network that would worsen or improve growth and survival under antibiotic stress; (3) use a synthetic biology approach to test these predictions and to quantify the extent of optimization in bacterial gene regulation. We will develop this approach using the powerful model system Escherichia coli and then apply our key findings to Staphylococcus aureus, a clinically more relevant pathogen.Our work will lead to the first quantitative genome-wide characterization of the extent to which microbial stress responses are optimized for responding to drugs. We anticipate that this knowledge can be exploited to improve drug treatments. The systematic fundamental research proposed here will reveal exploitable weaknesses in cellular responses to drugs. It will thus contribute to the alleviation of one of the most serious public health concerns of our time: the rapid spread of drug-resis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'ALFRED - Personal Interactive Assistant for Independent Living and Active Ageing' (ALFRED) under Seventh Framework.

assistant: **Objectives**

***Personal Interactive Assistant for Independent Living and Active Ageing***<br/>In an optimal society, elderly people will be able to live at their own homes with the possibility to act independently and to actively participate in society. The ALFRED proposal will contribute to this goal by providing a personal and interactive assistant for elderly people. ALFRED will foster independent living and active ageing, integrating interactive services for elderly people and for care-takers. It will prevail age-related  physical  and  cognitive  impairments through  the  effective  use  of  ICT  and  the  better coordination of care processes.In order to achieve those objectives, the project will create a virtual, interactive assistant for elderly people. This assistant will be realized as a mobile device running on day-to-day Android smartphones allowing a wide impact of the project results. ALFRED will be fully voice-controlled and combine latest scientific research results from mobile development, data management, context aware services, speech recognition and personal data management, combined with activities from behavioural and social science.<br/>In one sentence:<br/>ALFRED will realize a mobile, personalized Butler for elderly people helping them to stay independent, to coordinate with caregivers and to foster the active participation in society.<br/>ALFRED will be fully voice controlled and could – from a user perspective - also be described as Siri for supporting elderly people" but with an open and extendable app background and with a clear and precise focus on improving the life of elderly people. Developers will be able to contribute new "Health Apps" to ALFRED extending the platform and generating new added value.<br/>"
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'On-chip simultaneous intracellular recording and stimulation of electrical and biochemical activities from hundreds of neurons' under Seventh Framework.

assistant: **Concept**

In the BRAINSTORM project, we aim to develop an integrated system enabling on-chip intracellular recordings from a relatively large cultured neuronal network combined with chemical sensing and intracellular delivery of biologically active molecules. To achieve tight coupling with the cell membrane and enable efficient recordings, micronail-type probes will be integrated with a CMOS readout circuitry. These micronails are structured to operate either as intracellular microelectrodes or as intracellular micro-syringes allowing either chemical injection or to produce pressure or suction that will be used in additional to other procedures to penetrate the cell membrane. With appropriate bio-functionalization, the micro-nails inserted intracellularly will also serve as sensors for phosphorylation/ dephosphorylation reactions within living cells.<br/>The main technologies and methods to be developed in the BRAINSTORM project include:<br/>\tBiocompatible and CMOS compatible micronails and micro-syringes with integrated readout electronics;<br/>\tMicrofluidic system integrated with the CMOS-containing chip;<br/>\tProcedures to insert both nail types through the plasma membrane, into the neuronal cytosole;<br/>\tSurface chemistries allowing to achieve a Giga-Ohm (G) seal resistance between the disrupted plasma membrane and the nail;<br/>\tHigh signal-to-noise ratio recordings of neuronal electrical activity with micronail probes;<br/>\tOn-chip chemical delivery of chemicals;<br/>\tOn-chip sensing of intracellular kinase activities.<br/>
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Self-assembly of nano crystalline cellulose for lightweight cellular structures' (NCC-FOAM) under Seventh Framework.

assistant: **Objectives**

Cellulose, the primary structural component of plants, is the most ubiquitous and abundant organic compound on the planet. When cellulose fibrils are processed under carefully controlled conditions, it is possible to release highly crystalline nano-particles known as “nano crystalline cellulose (NCC)”. Recently, NCC-FOAM partners have developed a unique technique for self-assembling NCC into highly ordered “puff-pastry-like” layered cellular structures, i.e. foams. This self-assembly process is controllable, and the final cell structure can be modified to produce open or closed cell geometries depending on the requirements of the end application. Furthermore, the constituent NCC nanofibres are sustainably sourced from paper mill or forestry waste.The controlled patterning of the nano-structure during the self-assembly process facilitates the infusion of resins for stiffening / strengthening and the production of foams with customised internal structures and directional strength. The inherent strength of the NCC skeleton means that only minimal quantities of reinforcing resin are needed, resulting in lightweight and cost-effective foams.Within NCC-FOAM, the overall objective is to develop an NCC foam/resin composite that enables the design, development and processing of sustainable structural foam materials. The use of infused resins has yet to be developed, the challenge being to produce foams that are simultaneously structural, durable and renewably-sourced. If successful, this would represent a true breakthrough for rigid foam technology. Furthermore, NCC-FOAM aims to bring the production techniques closer to industrialisation by developing the methods and equipment to produce foams with meaningful practical dimensions (at least 1 m x 0.5 m x 20 mm). Such samples will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Mobile robots for inspection and maintenance activities in extensive industrial plants' to be submitted under Seventh Framework.

assistant: **Abstract**

Efficient and effective maintenance is crucial for all kind of industries. In the case of capital intensive investment industries it is even more relevant and has an important impact in the operation costs during the long life cycle of their production means.Besides the traditional maintenance problems of any industrial installation, this kind of facilities presents other additional challenging characteristics:-Extensive production facilities-Huge number of control points-Multiple inspection technologies to be used-Hazardous working conditionsMAINBOT proposes using service robots to autonomously execute inspection tasks in extensive industrial plants in equipment that is arranged horizontally (using ground robots) or vertically (climbing robots).The industrial objectives are:-Ubiquitous sensing-Leakage detection-Surface and internal monitoring of equipmentOur approach is not to develop robots from scratch but to take available wheeled mobile platforms and climbing robots that have already been tested in other related scenarios as starting point, and adapt them deploying innovative solutions in order to fulfill these industrial objectives:-Autonomous navigation: Robots (ground and climbing) must be able to autonomously navigate in a rather structured environment in a safe way.-Mobile manipulation of tools and sensing equipment for maintenance and inspection.-Sensor fusion: to exploit the information provided by multiple sensing technologies deployed in the robot.These industrial objectives will be instantiated in a real industrial scenario, a thermal solar plant that depicts common problems of this kind of plants:  230 hectares, 209.664 mirrors, 90 km of absorber tubes, huge tanks (Diam. 38 m, height 14m), harzardous working conditions.The operation of semi-autonomous or
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Teaching Greek in Eleventh-Century Byzantium. Schedography and Its Methods' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Schedography is a Byzantine method of teaching Greek grammar that was popular from the eleventh century to the early modern period. The study of this method enables a better understanding of 1) which kind of Greek was taught and how its teaching was conducted in medieval schools; 2) the influence of school curriculum on writing and reading practices in Byzantium; 3) the purposes of Byzantine education and cultural politics. The existent studies offer sound, but general, overviews and several schedographic sources are unedited. Furthermore, there is the lack of a consistent approach to the study of the edited schedographic sources. My project addresses this issue by looking at the eleventh century, when this method began to spread. I will frame schedography within the context of eleventh-century Byzantine culture and of contemporary school practices. Furthermore, I will examine the most relevant source for this period, the handbook by Longibardos, to describe its teaching method through a linguistic and stylistic analysis. My project will also lead to a critical edition of Longibardos handbook and other unedited eleventh-century schedographic remnants. TeaGre will offer both the first study of schedography and its early evolution as well as a consistent linguistic and stylistic approach to schedographic sources. The simultaneous presence of the ERC-funded projects MELA and EVWRIT at Ghent University places my MSCA Fellowship within a context of substantial and innovative research on Classical, Late Antique and Medieval Greek language and education. The edition of Longibardos and eleventh-century schedographic texts will also expand the database for the study of Greek literature and language that is currently being developed at Ghent University. Through this fellowship, I
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Early molecular and functional correlates of endothelial cell injury' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

Based on accumulating clinical-pathological evidence, endothelial cells (EC) are considered to be central to the injury" model for atheroma formation. Comprehensive goal of this project is to define the earliest molecular and functional response of quiescent, differentiated EC to potentially injurious stimuli, and to search for "natural antagonists" of such response, capable of preventing or reverting the functional consequences of EC injury.Based on their biological role as a continuous interface between the bloodstream and neighbouring tissues, and on accumulating clinical-pathological evidence, endothelial cells (EC) are considered to be central to the "injury" model for atheroma formation. It is thought that multiple risk factors lead to EC dysfunction, which in turn elicits a series of cellular interactions that culminate in the formation of atherosclerotic lesions. It is the aim of this project to gather several prominent groups in the fields of vascular biology, immunology and inflammation around one major unsolved biological problem, namely the early functional response of quiescent EC to potentially atherogenic stimuli. In an attempt to create a suitable in vitro model for the study of the aforementioned events, major emphasis will be initially placed on defining molecular parameters of EC quiescence, based on comparative in vivo and in vitro analysis of a number of early EC activation/proliferation markers. To this aim, we will create a Centralized Facility for the isolation, culture and characterisation of primary EC from various vascular areas. The Centralized Facility will devise the in vitro models for EC growth and differentiation, produce selected reagents, molecular probes and cDNA constructs and set the standards to be utilised by all participating tea
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Design, synthesis and evaluation of novel ligands of NPY Y1 receptor as potential anti-cancer drug carriers' (CANPY) targeting Seventh Framework.

assistant: **Abstract**

Neuropeptide Y (NPY) is a hormone which is the most abundant neuropeptide found in the mammalian central nervous system. It was proved that NPY is implicated in several highly important biological functions such as food intake, vasoconstriction, orexigenic effects, seizures, anxiety, thermogenesis, cardiac hypertrophy, pain modulation and hormone secretion. These activities are mediated by six receptors namely: Y1-Y6. Recently, it was proved that NPY is also involved in breast cancer growth. Experiments have shown that NPY Y1 receptor was expressed mainly in cancer cells, while NPY Y2 receptor was found mostly in healthy cells. Thus, selective ligands of NPY Y1 receptor could be very promising anti-cancer drug carriers, what was already shown in preliminary experiments at the laboratories of the host institutions. There are some known NPY receptors antagonists, both of peptidic (cyclic or linear constrained) and non-peptidic structure. The most promising are constrained linear peptide analogues of C-terminal fragment of NPY with beta-aminocyclopropanecarboxylic acids (beta-ACCs) as foldamers incorporated. However, these compounds exhibit some important disadvantages caused by their chemical reactivity. We propose application of beta-aminocyclopentanecarboxylic acids as peptide structure constraining units in order to obtain NPY Y1 active and selective ligands. Application of these natural amino acids analogues holds the promise to overcome all problems described for beta-ACCs. The synthesis of stereoisomerically pure beta-aminocyclopentanecarboxylic acids analogues of arginine and glutamine, followed by automated synthesis of NPY peptide analogues will give a vast library of potential NPY Y1 ligands. Their activities will be further verified by in vitro experiments and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Internet of Things (IoT) platform for concrete strength measurement and Machine Learning (ML) predictions in construction.'.

assistant: **Concept**

The construction industry, one of the oldest yet largest the world, is still forecasted to grow worldwide by 85% to $15.5 trillion by 2030. A major source of uncertainty during construction is the strength of the concrete. This variable is hard to accurately estimate. Well-known are traditional maturity models as a function of concrete temperature evolution, but these are not always accurate as the temperature also depends on the concrete mixture and the weather, and the current methods available to perform that action are also expensive and often impractical, construction workers still rely on their own experience to determine when concrete has sufficiently cured. Overestimating curing time leads to longer time elapsed (at 4 weeks of curing per floor, this has a huge economic impact). On the other hand, when curing times are not respected, consequences can be worse: the building can collapse leading to huge costs and lawsuits, not to mention possible accidents.cloudsensing provides concrete strength measurement sensors during curing, that can help construction companies cut time and improve security and project managing during the building process by giving accurate predictions on concrete maturity. The solution is offered as a service. Thanks to our cloud-based Internet of Things infrastructure, the captured data is processed seamlessly and provided to the user through a web interface, accessible worldwide. With an easy to scale solution like this, and a market as big and not exploited by digitalization like the construction industry is, the reachability of this project is global and exponential.