RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Linking plant-soil feedbacks to aboveground-belowground interactions for noxious weed control' (SOIL-4-CONTROL).

assistant: **Concept**

Recent research has proven that plant-soil feedbacks (PSF) can shape plant community composition, and that soil inoculation can be used to steer this. This provides the yet unexplored potential to target PSF for the control of noxious weeds, which are among the major threats to native plant diversity and forage yield. Recent studies showed that PSF-induced changes in plant chemistry can consecutively affect aboveground herbivory, a driver of plant performance that is used in weed biocontrol. I have a solid background in biocontrol and plant population dynamics. In my project SOIL-4-CONTROL I aim to provide a proof-of-principle that integrates effects of PSF and aboveground herbivory to control common ragwort, a worldwide toxic weed of grasslands rapidly expanding in Europe. The project will also yield fundamental knowledge on the (chemical) interplay between PSF and herbivores.Hosted by Leiden University, I will join an ongoing experiment of my supervisor Prof. Bezemer, who manipulated PSF at large scale in the field by soil inoculation. By combining analysis of unpublished data, experimentation in this field, a mesocosm experiment, and chemical analysis of the plants used, I will 1) examine soil-mediated effects on ragwort establishment in the field; 2) quantify the role of soil-mediated and herbivore community effects on ragwort performance in the field; 3) disentangle effects of PSF, specialist and generalist herbivores, and plant competition on ragwort performance. I will involve nature managers for future use of our expected results in grassland restoration. With my secondment host CABI, an environmental management organisation, I will explore wider applications of PSF in invasive plant management, as urged by the EU Regulation 1143/2014. I will engage the public f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Building the bridge from a microscopic towards a macroscopic description of the flow of amorphous media'.

assistant: **Concept**

Although disordered media are ubiquitous in everyday life in form of emulsions, pastes, granular materials, foams and metallic glasses, there is still little known about a possible macroscopic description of such type of materials. Despite the seemingly very different nature of the so called soft and hard versions of amorphous media, both lead to similar challenges when it comes to theoretical concepts and modeling issues. Here, we propose a bridging technique, starting from a first principle microscopic representation on the bases of molecular dynamics, towards a macroscopic mean field description of the plasticity of amorphous materials. We are considering disordered media, subject to a shear force, that will eventually cause the material to yield under sufficient loading. It is a commonly accepted point of view that the flow of glasses is a net result of individual structural rearrangements on the atomic or molecular level. Hence, it should be possible to derive a mesoscopic stochastic model, that allows for the application of statistical methods to conclude with the much sought after mean-field equations of amorphous plasticity. The establishment of such a description is not only of interest from a unifying theoretical point of view, but will also offer a key tool in practical engineering questions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Identification of signalling pathway components for pathogenic development of ustilago maydis' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Research objectives and content U. maydis is a model organism for studies on plant pathogen fungi. The aim of this project is to characterise signalling pathways components that act in relation with Gpa3, a G alpha subunit of heterotrimeric G protein in U. maydis pathogenic development. Gpa3 controls the cAMP pathway which plays a fundamental function in pathogenicity. Gpa3 also regulates a second pathway involved in tumor formation. Two different screen will be used to isolate genes regulating Gpa3 or genes involved in the second pathway controlled by Gpa3: a two-hybrid screen with Gpa3 as a target and a genetic screen based on the phenotype of an overactivated Gpa3 allele. The genes identified in these screens will then be submitted to an extensive genetic and physiological analysis with the help of knock-out mutants to understand the regulation of the two pathways and the biological relevance of their coordination. Training content (objective. benefit and expected impact) This project will allow me to extend the knowledge and expertise I gained during my Ph.D. on signalling pathways and fungi to aspects of pathogenic development in fungi. Due to the growing interest of companies and of the academic field in fungal pathogens this will broaden my carrier oportunities for the future. Links with industry / industrial relevance (22) Prof. Kahmann's group is actively cooperating with Bayer in a genome project with the aim to develop new antifungal targets.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Multi-Scale  Modeling of  Nano-Structured Polymeric Materials: From Chemistry to Materials Performance'.

assistant: **Innovation**

The practice of adding micron sized inorganic filler particles to reinforce polymeric materials can be traced back to the early years of the composite industry. With synthetic methods that can produce nanometer sized fillers, resulting in an enormous increase of surface area, polymers reinforced with nanoscale particles should show vastly improved properties. Yet, experimental evidence suggests that a simple extrapolation of the design paradigms of conventional composites cannot be used to predict the be-havior of nanocomposites. The origin of these differences between conventional and nanocomposites is still unknown. This, unfortunately, precludes yet any rational design.Though some property improvements have been achieved in nanocomposites, nanoparticle dispersion is difficult to control, with both thermodynamic and kinetic processes playing significant roles. It has been demonstrated that dispersed spherical nanoparticles can yield a range of multi-functional behavior, including a viscosity decrease, reduction of thermal deg-radation, increased mechanical damping, enriched electrical and/or magnetic performance and control of thermomechanical properties. Especially the decrease in viscosity is advantageous for injection-molding op-erations. Facile tuning of nanocomposite Tg could thus allow us to control the usable temperature range of these materials. Again, the physics under-pinning this behavior remains unresolved, primarily due to the poor understanding of the effects that particle/matrix interactions have on the composite behavior. This project aims at overcoming these deficiencies by a twofold strategy. This project will bring together a critical mass of scientists, from atomistic to finite-element modeling. The goal is to develop, implement and validate multi-
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'DEMONSTRATING LIQUID HYDROGEN FOR THE MARITIME SECTOR' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The develops and validates approaches to build (3MW) and scale (to 20MW) fuel cell approaches that lower operational cost (capex) and design cost of LH2 PEM operations. We integrate the technical solutions in a larger socio-technical system, in cooperation with linked projects and considerable investments that the project will help generate, with the result of providing what could be the first European maritime supply chain for LH2. This is helped by having the demonstrator as one of two planned sister ships that will connect a new hydrogen production facility with LH2 demand in a series of vessels. Most of these new vessels are in planning stages, and one of them are now built for operation in September 2021 (which then will be the first LH2 ship in operation, with a smaller 400 kW system, by consortia member Norled). HyShip combines the state of the art in ship design (building on the RHODA-method to incorporate logistics and fuel supply in the design process), intelligent energy management systems (lowering capex) and a range of novel conceptual designs of LH2 systems. The project will generate considerable value for Europe, both as its generic approaches will lower cost and time for new vessel projects, but also through its initiative to initiate a scalable distribution system where operators have stable and low-cost access to CertifyHy’ed Green H2. Behind the project is a combination of leading expertise on LH2, energy systems, business models and ship design. Industry partners cover the energy system (Kongsberg Maritime), LH2 systemsThis proposal, HyShip, is a response to topic “FCH-01-6-2020: Demonstration of liquid hydrogen as a fuel for segments of the waterborne sector”, in the “Fuel Cells and Hydrogen Joint Undertaking”. We propose development and validation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Implications and prospects of non-state post-secondary education initiatives in post-2021-coup Myanmar'.

assistant: **Innovation**

Myanmar, a diverse Southeast Asian nation with numerous ethnic and religious groups, faces socio-political conflicts that significantly affect its socio-economic development, neighboring countries, and the international community. The 2021 coup further impaired all sectors of its system, including education, resulting in millions of children being deprived of access to formal education. Various non-state educational services have emerged to address these gaps and provide alternatives to the junta's system; however, they face challenges in securing recognized qualifications and further learning opportunities for their students. Post-secondary non-state education initiatives are crucial for further learning opportunities for these non-state students who would serve as the change agents for the resilience of the socio-economic well-being of the country. This study, applying convenience sampling and case studies, aims to investigate the typology, challenges, coping strategies, and implications of these non-state post-secondary initiatives in post-2021-coup Myanmar. The study will employ principles of analytic eclecticism, which allows integration of diverse theoretical and academic perspectives to address real-world complexities. This study will be the first of its kind which explores the implications of these initiatives not only in the ethnic minority areas but also in the whole country, including the Bamar-dominated areas. Continuous monitoring and analysis are essential for regional and international stakeholders to comprehend the trajectory of the conflict in Myanmar. The findings from this research will elucidate the education landscape in Myanmar and broader theoretical concepts such as human rights, social agency theory, social mobility, structuralism, institutional
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Tracing of pulmonary neuro-immune networks' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Group 2 innate lymphoid cells (ILC2) are strategically positioned at mucosal surfaces, regulating mucosal defense, tissue homeostasis and inflammation. ILC2 contribute to the pathogenesis of allergic airway diseases, and pulmonary neurons have been also implicated in allergic conditions, such as asthma. Interestingly, recent studies demonstrated that ILC2 exert their function in the context of neuro-immune cell units that respond to environmental signals, steering mucosal immunity and repair. Nevertheless, the identity of the neuronal circuits innervating neuro-immune cell units and the nature of the bidirectional neuron-immune signals steering mucosal physiology remain elusive. Here, we hypothesize that pulmonary neuronal circuits provide and receive signals from ILC2, which steer immune responses in airway inflammation and infection.Initially we will use transgenic animals, engineered rabies virus and advanced imaging techniques to functionally map the innervation of neuron-ILC2 units. Sequentially, we will employ a combination of genetic, cellular and molecular approaches to determine how efferent neuronal activity controls pulmonary ILC2 biology and how ILC2-mediated effects impact on neuronal activity to maintain tissue homeostasis in the context of allergy and infection.Under this fellowship, we aim to establish how the interplay between neurons and immune cells steers tissue homeostasis. By identifying these new pathways, this action will contribute to the development of new therapeutic strategies in mucosal diseases that affect millions of people worldwide. Simultaneously, the fellowship will importantly strengthen the experienced researcher’s knowledge, skills and network to allow him to establish himself as an independent researcher.


**Keywords:** Neuro-immu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'MITIGATING ENVIRONMENTAL DISRUPTIVE EVENTS USING PEOPLE-CENTRIC PREDICTIVE DIGITAL TECHNOLOGIES TO IMPROVE DISASTER AND CLIMATE RESILIENCE' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Despite digital, predicative systems improving our ability to foresee the impact of disruptive climate events on our cities, the complexity of these environments, coupled with the lack of data to assess the impacts of such events, leaves large swathes of urban areas exposed to future events. These conditions are exacerbated by climate change, growing urban populations, and vulnerable, ill-equipped building stocks, designed for a shifting climate, thus not guaranteeing occupants safety and resilience of the interconnected built environment. Minority Report will develop and implement a co-creation framework, to support the delivery of a people-centric technology platform integrating: 1) innovative predictive digital technologies, 2) rigorous models (3+) for risk (including vulnerability and uncertainty) assessment and categorisation, 3) advanced weather forecasting and early warning for climate events, 4) BIM, digital twins, monitoring systems and DSS, 5) energy simulations and behavioural models based on AI (including evacuation models), 6) newly developed approaches from SSH (>20 co-creation events), 7) and deep renovation passports (3+, efficiently combining 10+ deep retrofit solutions). The final objective is to deliver the Minority Report technology platform for a functionally, sustainable circular value chain for construction and renovation of built environments, for improved climate change mitigation (heat waves, category 5 storms, wildfire) and disaster resilience (floods, earthquakes, etc.), through unprecedented environmental targets (70% Energy savings, 30% Carbon footprint reductions, 60% Environmental impact reduction). Minority Report will apply its universal co-creation framework across three demo sites representing three distinct climatic areas, situated i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Urban Phenology and Anthropogenic Climate Effects: getting the timing right in a warmer and more urban world' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Human-driven environmental change is affecting wildlife globally, with climate change and urbanisation having major impacts. For instance, warmer spring temperatures and urbanisation have been shown to independently advance the timing of recurring events in wild populations like leafing in trees, hatching in caterpillars, and egg laying in birds. Getting the timing right is critical for predator species like tits that rely on feeding prey resources like caterpillars to their chicks each spring. Tits can adjust the timing of their egg laying to match the hatching of their prey by responding to environmental cues like spring temperatures. In urban environments these cues may be highly modified and less reliable, which could negatively affect urban wildlife populations like tits if they can not track the timing of their prey. The UrbanPACE (Urban Phenology and Anthropogenic Climate Effects) research program will aim to establish whether urban tit populations across Europe adjust their egg laying to spring temperatures in the same way as nonurban populations, and evaluate the ability of urban populations to keep pace with climate change and further advances in spring timing. UrbanPACE will then determine whether spring timings are in sync between species in urban food webs. Using citizen science initiatives across the UK, I will explore whether climate change can increase mismatches between urban species by disrupting the timing of key events like leafing in trees and egg laying in tits. My results will provide new insights on how multiple processes of anthropogenic change interact to affect wildlife and evaluate whether urban populations are more vulnerable to a warming climate.


**Keywords:** urbanisation, urban evolutionary ecology, climate change, climate warming, phen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project '|Gestational signal and bile acid role in the enteroinsular axis' (GDMICP) targeting Seventh Framework.

assistant: **Abstract**

Normal gestation is associated with substantial changes in maternal metabolism including a marked increase in insulin resistance and mild cholestasis, hypercholesterolaemia, and hypertriglyceridemia at later gestational weeks. In some predisposed women, the metabolic changes are adequately severe to lead to development of gestational disorders of pregnancy including gestational diabetes mellitus (GDM) and intrahepatic cholestasis of pregnancy (ICP). Indeed, women with ICP are more susceptible to developing GDM and have significant biochemical and endocrine changes such as increased basal endogenous glucose production, decreased insulin sensitivity, and reduced GLP1 secretion from enteroendocrine L-cells that result in altered carbohydrate metabolism while they are cholestatic. The applicant hypothesises that reproductive hormones and their metabolites play an integral role in beta-cell adaptation in pregnancy through altered nuclear farnesoid-X-receptor (FXR) and G-protein coupled receptor TGR5 activity in the enteroendocrine L-cells and pancreatic islets. The applicant hypothesises that reproductive hormones and their metabolites play an integral role in beta-cell adaptation in pregnancy through altered nuclear farnesoid-X-receptor (FXR) and G-protein coupled receptor TGR5 activity in the enteroendocrine L-cells and pancreatic islets. There are emerging data to show that the bile acid receptors FXR and TGR5 play a pivotal role in glucose homeostasis and susceptibility to diabetes mellitus, but their role in altered glucose metabolism in pregnancy is poorly understood. The aberrant BA homeostasis during ICP may further contribute to the aetiology of GDM, by affecting FXR and TGR5 signalling in the in the gut and endocrine pancreas. It is also likely that that BA toxicit