RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'A natural, non-surgical, and safe facial filler which treats the root cause of facial ageing.' (Volumizer) under Horizon 2020.

assistant: **Objectives**

Aging is something that affects everyone. In order to combat the effects of aging, in a time where social and aesthetic appeal is so popular, people have turned to aesthetic injectables as a way to look and feel rejuvenated. Unfortunately, there are a multitude of problems with available facial fillers. Current solutions available on the market often have a multitude of side effects such as swelling, redness, bleeding or allergic reactions. Additionally, the procedures are costly, and due to the short term results, will produce a greater economic burden as continuous application is needed. PB&B has developed a unique anti-aging Volumizer that combats facial aging at the source by increasing local fat tissue in the face for a healthier and younger look. The solution is injected directly into the face, where over two months, the solution slowly evenly fills the wrinkles and deep fat tissue compartments. In order to reach commercialization, the Company will look to execute first in human trials and subsequent clinical trials to validate the efficacy. These results will be used in order to apply for CE certification. During the Phase 1 feasibility assessment PB&B will need to define a target segment of users within the markets of aesthetic products and facial injectables. A scaled up supply chain will need to be established in order to optimize distribution and market demand. Intellectual property will need to be patented after research and development has produced a product for commercialization.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Europrint' (1994-1998) under Fourth Framework.

assistant: **Objectives**

The project aim is to integrate all the dimensions of a network of printing firms (customer, design, manufacturing, logistics, marketing systems, including human resources training) in order to build a multisite multifirm European extended firm. The core elements are: Design: includes the communications between the printing firm and his customer in order to send by telematic means the image in low resolution quality during the prepress phase. Process control: the customer will have access to the process of the printing firm, being able to control the process of his product. Network integration: each firm will be the prepress the network and the printer of his own needs.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'A Nano-electrode chip for high-resolution/high-throughput cellular assays in cultured neurons including synaptic tranmission' (NeuroNanoChip).

assistant: **Innovation**

Cellular studies in neuroscience are hampered by the fact that in vitro cultures of primary neurons are complex, variable and heterogeneous, making studies on cultured neurons time consuming, labour intensive and not scalable. Especially for single cell studies on synaptic transmission and cellular trafficking, this is a major limitation. Both in academia and industry, mitotic cells are commonly used as a proxy for neurons (e.g. PC12 cells). However, while being less variable and better scalable, such cells model neurons only to a limited extent. These cells make no functional contacts (synapses) and do not have the same polarized organization that neurons have, which limits the validity for studies on synaptic transmission and cellular trafficking. Most commonly prescribed drugs for brain disorders target synapses. Yet, drug screening, lead finding/optimization and safety studies build either on cells that make no synapses or on labor-intensive low-throughput assays. Hence, new, standardized, scalable assays using real (synaptic) neurons, will provide a substantial step forward both for academia and industry.This application aims to develop a nano-electrode chip with an electrode array to stimulate, record and image many single neurons with high-resolution, for a period up to several weeks. This approach provides imaging data at single synapse and single organelle resolution and synaptic transmission data at high-throughput. Together, this will not only facilitate and standardize cellular assays using real neurons, but also upscale throughput 100 fold. In addition to the chip itself, we also see market potential for the method (growing/recording neurons on chips) and for a fee-for-service company that offers high throughput compound screening on synaptic neurons.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'International, Interdisciplinary & Intersectoral Postdoctoral Fellowships at the Paul Scherrer Institut' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Large-scale research facilities are enabling cutting edge research and innovation in important domains such as materials science, health and energy. A number of such accelerator facilities is currently under construction in Europe and will become operational within the next five years. Thus, there is a growing need for highly qualified researchers trained in interdisciplinary research at such facilities and also an increasing demand from companies to use these facilities for developing and testing innovative products.The Paul Scherrer Institut (PSI), one of Europes leading research centres and particularly renowned for its accelerator facilities and long-standing industry collaborations, intends to establish a novel post-doctoral research programme with a broad spectrum of interdisciplinary and inter-sectoral exchange opportunities.PSI features a unique combination of excellent research facilities, including neutron, muon and light sources and (as of 2019) an X-ray free electron laser, which all exceed the possibilities of universities or industrial research centres. Motivated by the successful implementation of the H2020 COFUND programme PSI-FELLOW-II-3i, PSI now wants to further advance in post-doctoral training and education and proposes to set up PSI-FELLOW-III-3I. This 5-year programme will offer a total of 60 fellowships of two years duration each. The fellowships will be awarded in two calls for proposals with 30 fellowships in each call. In order to maximise the benefit for the Fellows and offer the widest possible range of research topics, PSI has teamed up with 46 partner organisations (34 research institutions and 12 companies). The unique setup of PSI-FELLOW-III-3i will allow using synergies with other leading research institutions for the training of the ne
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'OPTimized conversion of residual wheat straw to bio-ISObutene for bio based CHEMicals' (OPTISOCHEM) targeting Horizon 2020.

assistant: **Abstract**

OPTISOCHEM goal is to demonstrate the performances, reliability as well as environmental and socio-economic sustainability of the entire value chains, for the transformation of excess wheat straw into bio-Isobutene (bio-IBN) derivatives. To achieve these goals a team of 6 partners, leaders in their field, originating from 4 EU-member states, will join efforts.OPTISOCHEM consists in showcasing the technical accessibility and economical sustainability of the value chains, from wheat straw to 2 different families of chemicals derived from bio-based IBN.These compounds, oligomers (DIB, TIB, TeIB) and polyisobutylenes (PIBs) are currently used in a wide range of applications such as lubricants, adhesives, sealants, flavors & fragrances and substituted phenols.This large market is today supplied entirely by products derived from fossil-based isobutene. Products derived from bio-based IBN, using the same process as fossil-based IBN, and with at least as good performances, would provide a renewable supply.OPTISOCHEM includes the development & up-scaling of bio-IBN production from wheat straw, followed by the production and validation at relevant scale -representative of commercial, established processes- of the bio-based derivatives. To this end, four ambitious objectives were defined:-Demonstrate the production of wheat straw hydrolysate (WSH) and establish a quality standard to feed the IBN fermentation unit,-Demonstrate the production of bio-IBN from WSH at pre-commercial scale,-Demonstrate the quality of end products obtained with bio-IBN as a feedstock and using traditional commercial processes designed for fossil based IBN,-Determine and validate the targeted technical, economic as well as environmental/social sustainability performances to be achieved for a commercial pl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Cohort studies on radon exposed populations : uranium miners or domestic exposure : aiming for a joint analysis' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Foreseen ResultsJoint analysis on Czech and French miners with low annual exposure to radon dicey products:- end of 1997 : validation of dosimetric history of each of the 5000 Czech miners and 4000 French miners. Description of the distribution of concomittant exposures to gamma radiation and to ore dust.- 1998 and 1999 : analysis of dose-response relationship between cumulative exposure and lung cancer risk, influence of dose-rate effect, of gamma and ore dust exposure.- 1997-1998 : validation of the data concerning the domestic radon study.Epidemiological cohort studies on French and Czech uranium miners have been published recently : they demonstrate a clear increase of lung cancer mortality with increasing cumulated radon exposure. Other components; more or less linked to this cumulated exposure have been tested : duration of exposure, dose-rate, age since first or last exposure. The way how this cumulated exposure has been protracted over time and how it may influence the dose-response relationship is one of the major points of our collaborative studies. Czech and French uranium miners have experienced different radon concentrations in uranium mining, and we will be able to study the risk down to less than 1 WLM per year; history of exposure shows that exposure levels have changed in time and those miners having experienced low exposure per year, have entered later the mines and are younger than those having experienced high annual exposures. Taking in account these time dependent variables linked both to exposure and to risk are one of the main methodological objectives of these cohort studies. Parallel to the uranium miners studies, an exchange of experience between the three partners will be organized in order to favor the study of domestic radon in Czech republ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Structure-activity relationships for reactions in the degradation of biogenic volatile organic compounds'.

assistant: **Objectives**

To understand the contribution of biogenic emissions (e.g. isoprene, monoterpenes) to various aspects of tropospheric chemistry (e.g. ozone and aerosolLaboratory studies have been performed on the importance of ozone reactions with biogenic volotile organic compounds (VOC), the atmospheric oxidation of halogenated organic compounds used as fuel additives and the atmospheric oxidation of halogenated compounds af anthropogenic and biogenic origin.Reactions of ozone with biogenic compoundsKinetics and project studies of reactions of ozone with a variety of biogenic compounds. Emphasis has been placed on ozone with alkenes, since experimental evidence that these reactions lead to the formation of OH radicals. The reactions with a series of alkenes have been investigated and the OH radical yoeld rationalized in terms of the molecular stucture of the alkenes.Atmospheric oxidation of oxygenated VOCsThe rate constants of the reaction of OH radicals with a series of alcohols, esters and ethers have been measured. studies have focused on difunctional cmpounds such as CH3O(CH2)nOCH3 which have potential applications as fuel additives and water based solvents in industry, Structure reactivity relationships are being developed to facilitate prediction of the kinetics of atmosperic oxygen and hence tropospheric lifetimes.Atmospheric oxidation of halogenated organic compoundsRate constants have been determined fro the reaction of hydroxyl radicals with a number of fluorinated ethers and chlorinated alkanes and alkenes. The results give estimates of the atmospheric lifetimes of these compounds and provide structure reactivity information on the reactions. A detailed knowledge of the elementary reactions taking place in the gas phase degradation of biogenic  compounds is required. The n
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for '‘Seeing’ with the ears, hands and bionic eyes: from theories about brain organization to visual rehabilitation' to be submitted under Seventh Framework.

assistant: **Abstract**

My lab's work ranges from basic science, querying brain plasticity and sensory integration, to technological developments, allowing the blind to be more independent and even “see” using sounds and touch similar to bats and dolphins (a.k.a. Sensory Substitution Devices, SSDs), and back to applying these devices in research. We propose that, with proper training, any brain area or network can change the type of sensory input it uses to retrieve behaviorally task-relevant information within a matter of days. If this is true, it can have far reaching implications also for clinical rehabilitation. To achieve this, we are developing several innovative SSDs which encode the most crucial aspects of vision and increase their accessibility the blind, along with targeted, structured training protocols both in virtual environments and in real life. For instance, the “EyeMusic”, encodes colored complex images using pleasant musical scales and instruments, and the “EyeCane”, a palm-size cane, which encodes distance and depth in several directions accurately and efficiently. We provide preliminary but compelling evidence that following such training, SSDs can enable almost blind to recognize daily objects, colors, faces and facial expressions, read street signs, and aiding mobility and navigation. SSDs can also be used in conjunction with (any) invasive approach for visual rehabilitation. We are developing a novel hybrid Visual Rehabilitation Device which combines SSD and bionic eyes. In this set up, the SSDs is used in training the brain to “see” prior to surgery, in providing explanatory signal after surgery and in augmenting the capabilities of the bionic-eyes using information arriving from the same image. We will chart the dynamics of the plastic changes in the brain by performin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Specificity and communication in interactions maculinea butterflies and their myrmica ant hosts'.

assistant: **Innovation**

Research objectives and content The objective of the project is to examine the specificity of host use by parasitic Maculinea butterflies, and to relate this directly to communication between ffie parasites and their Myrmica ant hosts. This system is unique in providing documented geographical variation in host use by what are regarded as a single species of host-specific parasites. Specificity will be examined at both the species and population level. Patterns of specificity will be studied using genetic markers, and their ecological significance tested in laboratory cross-infection experiments. Chemical, and vibrational communication between butterflies and ants will be examined using chromatographic techniques and recording-and-playback experiments respectively. The results will provide information that is vital for the management of these endangered butterflies in Europe, as well as contributing to some current problems in parasite-host evolution. Training content (objective, benefit and expected impact) During the project I will gain experience of population genetic analysis using molecular techniques, as well as use of specialised equipment for examining chemical and vibrational communication. Training in molecular genetic techniques will be particularly useful for my career development, as this is a vital tool for examining evolution which can be applied to many different biological systems.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Abandoning ship – sex and dormancy strategies in Daphnia' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The ability to switch between sexual and asexual reproduction may be critical for many taxa when securing survival in varying environmental conditions. For these organisms, sex is often associated with harsh conditions, typically found at the end of the growing season. Sexual recombination in facultative sexuals commonly results in the formation of a dormant form that is considered a strategy to overcome adverse environmental conditions. When engaging in sex, organisms have been shown to specialize by producing males or sexual females, but not necessarily both, potentially reducing the chance of inbreeding. Sexual reproduction among those ‘gender specialists’ may vary with contrasting environments. The association between different environments and the production of a distinct phenotype (i.e., males or sexual females) suggests that sex specialisation may be adaptive. However, little is known about whether sex specialization is associated more with inbreeding avoidance or local adaptation. In the work proposed here, we will use the ecological and genomic model organism Daphnia to experimentally test if genetic variation in the production of males and ephippia is strongly environment dependent or not. Specifically, we will use a high-throughput phenotyping approach to assess genotype x environment interaction among 100 Daphnia pulex genotypes originating from a UK meta-population. We will also assess the molecular mechanisms that drive the production of males and ephippia. Using a gene expression approach, we aim to resolve the network of gene expressions that underpins the shift from diploid egg production to male and ephippia production. Obtained data will help to resolve whether inbreeding avoidance or local adaptation/dormancy underpins sexual specialisation. Findings
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'A Competitive Intelligence Cloud/HPC Platform for AI-based STI Policy Making' to be submitted under Horizon 2020.

assistant: **Abstract**

IntelComp sets out to build an innovative Cloud Platform that will offer Artificial Intelligence based services to public administrators and policy makers across Europe for data- and evidence-driven policy design and implementation in the field of Science, Technology and Innovation (STI) policy. Large STI datasets are processed on High Performance Computing (HPC) environment part of the European Open Science Cloud (EOSC) imitative. Public administration at all geographical and organizational levels, STI stakeholders and civil society produce a great amount of dynamic, multilingual and heterogeneous data (i.e. national STI strategies, plans and work programmes, calls, projects, reports, scientific publications, patents, dissemination articles, etc.), so understanding and analyzing this data is crucial for evidence-based policy making. The objective of IntelComp is to deliver a platform that provides tools for assisting the whole spectrum of STI policy, i.e., agenda setting, modeling design, implementation, monitoring and evaluation. It will do so by involving multi-disciplinary teams to co-develop innovative analytics services, Natural Language Processing pipelines and Artificial Intelligence workflows and by exploiting open data, services and computational resources from the EOSC, HPC environments and federated distributed operations at the European Union, national and regional level. It will ensure a cooperative environment where different actors can visualize, interact and analyze information. Through co-creation, IntelComp will adopt a living labs approach and will engage public policy makers, academia, industry, SMEs, local actors, civil society and citizens to explore, experiment with and evaluate STI policies at all stages. IntelComp will be targeting domains alig