RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Terahertz ultra-massive multiple-input multiple-output systems' (2021-2027).

assistant: **Innovation**

As the deployment of 5G networks expands into the millimeter-wave band, potentially reaching data speeds of 100 Gbps, the future of 6G networks is expected to leverage the terahertz (THz) frequency bands for even higher data transmission rates surpassing the 1 Tbps threshold. In this fellowship, under the supervision of Prof. Emil Björnson at the KTH Royal Institute of Technology, Sweden, the researcher, Boyu Ning, will focus on developing a new THz ultra-massive multiple-input multiple-output (UM-MIMO) paradigm and efficient algorithms for channel estimation, user localization, and data transmission, to achieve a complete way to operate the physical layer in THz UM-MIMO.  With a dedicated research focus on THz communications over the past five years, Boyu Ning has established myself as a prominent doctoral candidate in this field, publishing over 50 top-tier IEEE journal and conference papers. Prof. Emil Björnson (IEEE Fellow) has performed MIMO research since 2006, with more than 31000 citations and more than 30 patent applications. The integration of THz technology and MIMO methodologies stands as a pivotal juncture in advancing THz UM-MIMO. This strategic confluence necessitates a symbiotic partnership between experts versed in THz systems and MIMO paradigms, rendering Prof. Emil Björnson an ideal supervisor for this fellowship. To maximize the impact of the research conducted, the researcher will prepare scientific research results for publication in leading journals such as IEEE TWC and IEEE TCOM, and will present conference papers at premier international conferences such as IEEE GLOBECOM and IEEE ICC. The results will also be disseminated through tutorials, videos, and simulation code. By investing in cutting-edge research in this field, the European Union (EU)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'European Review of Injury Surveillance and Control' under Fourth Framework.

assistant: **Concept**

. To review the current status of injury surveillance and control (lSC) in EU countries. To develop a consensus Statement of Good Practice of ISC. To recommend measures for the improvement of ISC in the EU in the next centuryThe essence of EURORlSC is the creation of a goal-oriented collaborative partnership of injury experts in the EU supported by a network resource in the form of a Clearinghouse.Injury surveillance is widely acknowledged to hold the key to effective injury prevention. Existing injury surveillance and control (ISC) systems in the European Union (EU) are limited in number, scope and population coverage. The best known transnational injury surveillance system is the European Home and Leisure Accident Surveillance System (EHLPSS), an EC demonstration project. While EHLASS represents a formidable administrative and technological achievement, it nevertheless has considerable unfulfilled potential. The proposed EURORISC concerted action project is unprecedented in that it aims to undertake a comprehensive review of current practice and future needs for ISC in the EU.It will comprise three phases:Phase 1: The reality - a survey of the current position Objectives:i) to describe the contemporary epidemiology of injury in the countries of the EU;ii) to identify current ISC activities throughout the EU.Phase 2: The ideal - a consensus Statement of Good Practice Objectives:i) to develop criteria for the evaluation of ISC;ii) to review the world literature on ISC;iii) to articulate a Statement of Good ISC Practice.Phase 3: The future - overcoming obstacles to effective ISC Obiectives:i) to compare current ISC in the EU with the Statement of good Practice;ii) to recommend measures designed to improve the efficiency and effectiveness of ISC in the EU in the next cent
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Novel treatment for peripheral arterial disease' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Peripheral Arterial Disease (PAD) is caused by the deposition of fatty material on the inner walls of peripheral arteries causing reducing perfusion and local nutrition to the muscles and skin. The condition affect 202 million people globally and is increasing at a rate of 20% per annum due to an aging population and epidemic growth of diabetes. The social costs amounts to $210 - 380 billion per annum. Behavioural changes such as smoking cessation, healthy nutrition and exercise is recommended to reduce impact and risk. When the condition worsens, patients ability to walk and exercise is reduced. When disease progress to critical limb ischemia (unbearable pain and chronic wounds), the patients follow a trajectory towards costly vascular surgery or amputation.FlowOx targets the gap in care with a patented, cost effective and clinically promising home treatment solution. In order to secure the successful introduction of FlowOx into the market by 2020, resources are required to fill the following gaps in innovation:1) strong clinical evidence of efficacy 2) health economic assessment 3) design for large scale manufacturing and 4) a validated commercial model Germany, UK and Scandinavia. These 4 challenges will be addressed in the FlowOx project over a 30-month period. The Fast Track to Innovation Pilot program was selected to support a resource demanding and technically challenging stage of the product roadmap. The support enables Otivio to join forces with a medical device manufacturer, Innokas Medical, Finland, and UK based Univ. of Salford and Univ. of Bangor with extensive experience in clinical and health economic studies. The FlowOx project enables Otivio and Innokas to enter the world-wide PAD market, gaining a strong market positon with a home care device for PAD t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Virulence factors of facultative pathogens and their role outside the human host' under Seventh Framework.

assistant: **Concept**

The etiologic agent of cholera, Vibrio cholerae, is an important cause of human morbidity and mortality, particularly in developing countries or following environmental disasters.  The watery diarrhea characteristic of cholera results from the action of bacterial virulence determinants, notably cholera toxin, which gene has been acquired by horizontal gene transfer. V. cholerae as a facultative pathogen commonly occurs in aquatic ecosystems, its true habitat, where it intimately associates with phyto- and zooplankton.My proposal will investigate intensively the interaction between V. cholerae and non-vertebrate animals in marine environments and test the hypothesis that virulence determinants important in human disease are also critical for colonization of these environmental hosts. There are three interlinked specific aims:Aim 1: Establish microcosms involving V. cholerae and its environmental hosts.Aim 2: Identify factors that are beneficial for both lifestyles of V. cholerae.Aim 3: Determine the role of known virulence factors in nature.There is growing concern about the (re-)emergence of infectious agents and the threat this poses to human health particularly in the context of climate change. The sporadic and unpredictable nature of cholera epidemics has long puzzled environmental microbiologists. The interdisciplinary research proposed in this study will provide the missing link between the ecology and evolution of V. cholerae on the one hand and its pathogenesis on the other. Knowledge of how an innocuous microbe in an aquatic environment can become a major human pathogen and identification of the factors responsible are both of considerable importance.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Repurposed Drug Neuroprotective Nanocarriers for Targeting Retinal Diseases'.

assistant: **Concept**

Retinitis pigmentosa is one of the main causes of irreversible blindness worldwide, yet the only intraocular approved treatment, Luxturna®, is suitable for less than 1% of patients. A promising way to tackle this disease is by targeting protein aggregation, a process involved in all forms of retinitis pigmentosa and other brain-related disorders. Most potential treatments are still in early stages, so repurposing existing drugs with known safety records can speed up the development of effective therapies.Tideglusib, a drug initially approved for the treatment of progressive supranuclear palsy, has shown promise in reducing protein aggregation, thereby offering protection against neurodegeneration. However, it needs to reach the retina, its therapeutical target, to be effective. The RENASCENT project aims to create a new treatment for all retinitis pigmentosa patients by developing a cutting-edge formulation to deliver tideglusib to the retina via subconjunctival injection, bypassing the challenges of current intraocular treatments that are poorly tolerated.This MSCA Postdoctoral Fellowship will be conducted over two years at the University of Parma in Italy, under the guidance of Prof. Silvia Pescina, a leading expert in eye drug delivery. The project also includes a collaboration with the University of Alicante (Spain) and a visit to the European Synchrotron Radiation Facility (France) to explore the physical properties and neuroscience aspects of the designed formulation. Alongside the scientific work, there will be communication activities to engage the public and share the findings also to an academic audience, providing valuable experience in Ophthalmology and Pharmaceutical Technology for Dr. Marco Brugnera. This project is a significant opportunity for his career
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Rough path theory, differential equations and stochastic analysis'.

assistant: **Concept**

We propose to study stochastic (classical and partial) differential equations and various topics of stochastic analysis, with particular focus on the interplay with T. Lyons' rough path theory:1) There is deep link, due to P. Malliavin, between the theory of hypoelliptic second order partial differential operators and certain smoothness properties of diffusion processes, constructed via stochastic differential equations. There is increasing evidence (F. Baudoin, M. Hairer &) that a Markovian (=PDE) structure is dispensable and that Hoermander type results are a robust feature of stochastic differential equations driven by non-degenerate Gaussian processes; many pressing questions have thus appeared.2) We return to the works of P.L. Lions and P. Souganidis (1998-2003) on a path-wise theory of fully non-linear stochastic partial differential equations in viscosity sense. More specifically, we propose a  rough  path-wise theory for such equations. This would in fact combine the best of two worlds (the stability properties of viscosity solutions vs. the smoothness of the Ito-map in rough path metrics) to the common goal of the analysis of stochastic partial differential equations. On a related topic, we have well-founded hope that rough paths are the key to make the duality formulation for control problems a la L.C.G. Rogers (2008) work in a continuous setting.3) Rough path methods should be studied in the context of (not necessarily continuous) semi-martingales, bridging the current gap between classical stochastic integration and its rough path counterpart. Related applications are far-reaching, and include, as conjectured by J. Teichmann, Donsker type results for the cubature tree (Lyons-Victoir s powerful alternative to Monte Carlo).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Interoperable end-to-end platform of scalable and sustainable high-throughput technologies for DNA-based digital data storage' (PEARL-DNA).

assistant: **Concept**

Our data-intensive era requires innovative and sustainable data storage solutions: current technologies have hit several sustainability limits in terms of storage capacity, energy consumption and use of rare and toxic materials. A significant share of new data is not yet stored beyond the short term, and conventional storage media do not offer adequate longevity, data density or cost efficiency characteristics to meet global demand. As nature’s data storage medium of choice, DNA offers an ideal alternative with unmatched information density and stability for millennia. The PEARL-DNA multidisciplinary consortium aims to develop and assess a novel high-throughput, end-to-end PoC platform for DNA-based digital data storage built on scalable and interoperable systems for block-by-block assembled DNA. The consortium aims to substantially advance the state of the art in terms of throughput and data integrity for the mid- to long-term storage of large datasets. The innovative platform will enable 10+ MB/s data-to-DNA writing speeds in sub-nanolitre droplet DNA assembly for the very first time, while eliminating the need for plastic consumables. In addition, novel error correction, compression and data standard modules will be developed, as well as a cutting-edge storage container system for maintenance-free, long-term preservation of DNA at room temperature. The fully modular and interoperable platform will facilitate integration with other DNA-based storage solutions and accelerate the uptake of the technology. Using DNA as a commercially viable and widely applicable data storage medium strongly relies on intertwining a wide range of technologies from multiple disciplines, such as life sciences, engineering and information technology. PEARL-DNA brings together three renowned
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'TUNABLE MODE RANDOM FIBER LASER FOR MODE DIVISION MULTIPLEXING LASER SOURCE' under Horizon 2020.

assistant: **Concept**

The evolution of the bandwidth demand in optical fiber communication system in the Europe region keeps increasing year after year. As for now, most of these demands are supported by the WDM system of optical communication network. It is forecasted that this increasing bandwidth demand could not be supported any more data traffics in the future due to the consumption growth of new applications. In this regards, a new system for solving this issue is becoming all the necessary. An alternative which is forecasted to be able to fulfill this demand is Mode Division Multiplexing (MDM). MDM basically is based on a concept developed for increasing the optical data transmission capacity within the optical fiber itself. Thus, this project will be carried out to investigate the mode tuning of random fiber laser for the application in MDM system. The main objective of this project is to generate a laser with various modes which can be tuned by using few mode fiber and will be using random fiber laser. The purpose of using random fiber laser is because the conventional rare earth based fiber laser such as Erbium and Ytterbium are not optimized for lasing at higher order mode than the fundamental mode LP01. Investigation on mode tunability will be carried out using micro fiber technology and also fiber Bragg grating technology whereby the combination of these two technologies will be functioning as the tunable and filtering element. Also, in this project, new ideas and concepts will be developed whereby the generation of a laser with various modes will probably generate new concepts and findings, not only for MDM system, but also for the device to support this application in the future. In this regards, this research is very significant, in conjunction with the growth of the bandwidt
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Discovering susceptibility genes to Rhizoctonia solani in rice as breeding targets for sheath blight disease resistance' in the context of a Horizon 2020 call.

assistant: **Objectives**

Rice is a main staple food providing more than 50 percent of the world’s calories intake. However, grain yield and quality are drastically reduced by the sheath blight disease (ShBD), the second most important disease. ShBD is caused by the soilborne, necrotrophic fungal pathogen, Rhizoctonia solani. No rice germplasm providing complete resistance is available, preventing improvement of cultivated rice varieties. Generally, dominant resistance genes are used to generate resistance to pathogens. However, these narrow-spectrum genes can be easily overcome by pathogens. Therefore, the best approach to acquire broad-spectrum resistance is to employ altered susceptibility genes (S genes). S genes encode susceptibility factors, facilitate pathogen infection and support compatibility. The molecular mechanisms underlying susceptibility to R. solani are largely unknown. Recently, it has been recognized that necrotrophic pathogens have a short biotrophic phase during infection. In “RiZeSisT” -Rice rhiZoctonia reSisTance-  I will identify rice S genes that are essential to establish the early (biotrophic) infection of R. solani. I will exploit mutated (incompatible) S gene(s) to generate resistance to ShBD. After this project we will generate non-GMO mutants for improving elite varieties for broad-spectrum resistance to ShBD. KeyGene acts at the forefront of new technologies and traits to support the development of new and improved crops. Executing “RiZeSisT” at KeyGene, will enable me to use cutting-edge technologies, bioinformatics & data science expertise and plant-based trait platforms to discover the S genes. This is an innovative strategy that has not been used for this pathosystem. Furthermore, there is a high chance to translate my obtained knowledge to generate resistance
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Perception of signals under varying conditions: implications of proportional processing of signal magnitude for signal design', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Individuals evaluate one another during interactions using assessment signals that indicate quality, and these signals vary across individuals, reflecting variation in signaler quality. For example, green swordtail (Xiphophorus helleri) females assess the length of an extended caudal fin (known as a sword) on males, which ranges in length from 10-70mm in nature, during mate choice, and males evaluate one another’s swords during agonistic encounters. Models of signal evolution implicitly assume that signals are perceived continuously, meaning that each change in signal magnitude is both perceived by the receiver and results in a concomitant change in receiver response. Increasing evidence, however, shows that signals across modalities, from acoustic signals to color-based visual signals, can be perceived discontinuously. One mechanism by which stimuli can be perceived discontinuously is called proportional processing, which follows Weber’s law. Under proportional processing, a viewer can more readily discriminate between two stimuli that differ by a certain amount when both of those stimuli are of low magnitude, compared with two stimuli that differ by the same amount but are both high magnitude. Although proportional processing has been shown to operate across a variety of taxa and modalities, no study has yet tested for proportional processing of a visual signal. This project will (1) test whether signal magnitude, i.e. male sword length, is perceived continuously or proportionally by female and male swordtails; (2) assess how perception of stimulus magnitude is affected by variation in environmental conditions, by manipulating both the visual and auditory environment; (3) compare perception of signal-relevant (bars) and signal-irrelevant (circles) stimuli, between a s