RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Chrysophycean cysts from europe as a tool for palaeoenvironmental reconstruction (CREATE)' under Fifth Framework.

assistant: **Concept**

The first objective is to develop an air-temperature transfer function, based on chrysophycean cysts, to be applied in different lake ecosystems throughout Europe. The second is to validate the developed transfer function using high resolution 210Pb sediment records and compare the reconstructed temperatures with the instrumental record. To achieve these objectives, it is necessary to build on the cyst calibration data-set, that is already available for the Pyrenees (105 lakes), specifically by adding new lakes that increase the dissolved organic carbon and temperature ranges of the data-set. These conditions can be covered adding lakes from Scotland and Norway (90 lakes). Test sediment cores will be taken from Norway and Scotland and dated by 210Pb methods. The air temperature reconstruction will be validated by comparing the results from sediment analyses with the available instrumental climate record. In particular an attempt will be made to identify cyst signals associated with the North Atlantic Oscillation in the recent record, and propagate backwards in time the signal of the NAO. The most innovative aspect is the development of a powerful new tool for reconstruction of continental air temperatures. It is particularly relevant to problems of climate variability over the Holocene, and would be especially valuable for application to sites in north-west Europe that are strongly influenced by Atlantic Ocean pressure and sea-surface temperature variability.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Broadening the coverage of metabolites in faeces through advanced analytical strategies' under Horizon Europe.

assistant: **Concept**

The analysis of human faecal metabolites can provide an insight into metabolic interactions between gut microbiota and the host organism; furthermore, it can be instrumental to not only treat, but also intercept or even prevent diseases. The present project proposes the development, validation and application of two complementary chromatographic platforms (GC/MS and LC-IM-QTOF-MS) in combination with solid phase microextraction (SPME) as a greener, high throughput sample preparation method for faecal metabolites study, more specifically, volatile organic compounds (VOCs) and bile acids (BAs). As a proof-of-concept, faeces from patients with anorexia nervosa (AN) will be analyzed and compared to that obtained from health individuals (controls) aiming to identify possible biomarkers and/or associations between metabolites. Furthermore, patients with AN display nutritional, metabolic, hypothalamic, and endocrine abnormalities, which can lead to them presenting modified microbiota. Interestingly, eventhough AN patients often avoid cholesterol-rich food, hypercholesterolemia is commonly diagnosed in AN patients. In this context, the current project also aims to investigate possible correlations between short chain fatty acids and bile acids levels, BMI, and blood lipidic profile (cholesterol) for patients with anorexia nervosa (AN) and healthy individuals (controls) individuals that could shed light into the gut health, development of hypercholesterolemia, and establish the microbiota role in the evolution of the disease. Moreover, this project aims to develop simple to execute, greener, automated sample preparation for faecal samples that could be easily implemented in clinical settings.


**Keywords:** solid phase microextraction,  faeces,  metabolites,  biomarkers, volati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Virtual Research Lab for a Knowledge Community in Production' (2002-2006), addressing dissemination and exploitation.

assistant: **Impact**

The globalisation of the production systems will result in Europe losing its know-how in the technologies of production. However, high quality products at low costs, accommodating sustainable development and the need for shorter lead times can only be obtained by integrating the production phase in the design stage.It has also been requested to integrate new technologies of production to design innovative products. This can be obtained by installing a virtual production system. Through the VRL-KCiP network of excellence, Europe will be able to federate many research teams in the field of design, production and innovation and thus preserve the common inheritance of manufacturing processes while carrying out a collaborative system of design integrating a module of virtual production. 20 research units, gathering 150 researchers, decided to work together in order to provide a strong integration of their teams and thus break the fragmentation of European research in this area and work more efficiently.A new organisation of the research system must lead to a clearer vision of the research orientations, an improvement of the quality of research by exploiting complementarities, avoiding duplication, and finally a better impact on our industry for the good health of our society.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Nonlinear optical coatings at high intensities' (NICOS), addressing dissemination and exploitation.

assistant: **Impact**

Optical interference coatings have become a key enabling technology for many laser systems. Modern oscillators and amplifiers are capable of generating ultrashort pulses with energies of several tens of µJ at repetition rates of more than 10 MHz, resulting in several hundreds of watts of average output power. Under the illumination of optical coatings by such intense optical fields, the nonlinear effects manifest themselves. These effects can be exploited for development of novel types of nonlinear optical (NLO) laser components: dielectric multilayer coatings with specified nonlinear properties. In order to use the potential of dielectric coatings as NLO devices, the nonlinear behaviour of dielectric multilayers at intensities which are, from one side, high enough to activate nonlinearities and lower, from other side, than laser damage threshold, has to be carefully explored. As structures of films differ from the ones of bulk materials, then characterization of nonlinear effects in dielectric coatings is to be carried out and numerical values of coatings’ nonlinear parameters are be estimated.NICOS project is aimed at accurate and reliable characterization of nonlinear effects in dielectric coatings and development of new types of NLO dielectric multilayers for laser applications. In order to resolve project tasks, a combination of four main elements is required: (1) laser systems to generate high intensity pulses inducing nonlinear effects in multilayers, (2) deposition plants to produce the coatings, (3) measurement tools to characterize the effects and (4) background in modelling and optical technology. Unique research facilities of the Host Institution together with Applicant’s expertise in optical coatings provide a basis for successful implementation of the proj
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'DIGITAfrica, Towards a comprehensive pan-African research infrastructure in Digital Sciences'.

assistant: **Innovation**

The African Union's Science, Technology, and Innovation Strategy for Africa (STISA-2024) positions science, technology, and innovation as fundamental drivers of Africa’s socio-economic development and growth. It emphasizes the need to strengthen three main pillars: 1) Building/upgrading Research Infrastructures (RI), 2) Enhancing professional and technical competencies, and 3) Promoting entrepreneurship and innovation. It also highlights the importance of fostering collaboration among African countries and establishing partnerships with international stakeholders.ICT (Information and Communication Technologies) is identified as a critical priority sector. Areas such as computer science, telecommunications, cloud computing, big data, artificial intelligence, machine learning, security, and IoT offer potential for creating new knowledge, research capacities, and industries that address African and global challenges.DIGITAfrica aims to lay the foundations of a pan-African comprehensive RI in Digital Sciences, which will have a transformative impact on AU-EU shared R&I, as well as innovative education and training. DIGITAfrica will prepare the transformation of this partnership into a sustained research initiative in common strategic fields.Drawing from the expertise of partners across five AU countries, each with a strong background and representing diverse African contexts, alongside EU partners who coordinate the first two ESFRI DIGIT RIs dedicated to Digital Sciences, DIGITAfrica aims to exchange experiences, consult stakeholders, and foster dialogue to collaboratively develop a strategic approach.DIGITAfrica will serve as a catalyst for realizing the vision of a pan-African Digital RI and should become a cornerstone of Euro-African cooperation in R&I. The impact of DIG
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Dynamics underlying learning in complex environments' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Learning and adaptation play a central role in interacting with a changing environment, yet the neural substrateunderlying such flexible, goal-directed behaviors has remained elusive. Neuroscience experiments have traditionally focused on how individual brain regions perform abstract, highly simplified tasks. However, recent technological advances, coupled with powerful AI-accelerated software, have rapidly enabled the monitoring of large populations of neurons over many days, across multiple brain regions, and during increasingly complex, naturalistic behaviors. Yet even with such data within our reach, we still lack the theoretical and quantitative tools that are necessary to understand the fundamental principles guiding learning in neural populations. DULCE aims to fill this gap by establishing a unified framework to understand learning in complex environments. The core hypothesis of DULCE is that in naturalistic conditions, learning engages multiple co-occurring learning processes that are distributed across the brain, and which work together to reshape neural dynamics to perform new tasks. As such, DULCE aims to uncover the behavioral, population- level, and synaptic learning rules responsible for guiding learning in complex environments. By interweaving statistical modelling, dynamical systems theory and machine learning, DULCE will: i) Develop hierarchical models of behavior that can disentangle the rules governing simultaneously occurring learning processes. ii) Provide a unified theory of how region-specific learning rules in the cortex, cerebellum, and striatum coordinate to form a distributed learning system. iii) Develop interpretable dimensionality reduction methods to identify the rules governing how task-relevant dynamics evolve in large-scale neural data
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Colloidal two-dimensional InP nanocrystals' under Horizon 2020.

assistant: **Concept**

Colloidal semiconductor nanocrystals (NCs) attract immense interest both from the scientific community and industrial companies/startups, due to their unique optical properties that are tunable in a wide range through changing their composition, size, shape, etc. However, currently, the implementation of the well-developed NCs in consumer products is hindered by the presence of toxic cadmium and the development of “Cd-free” NCs, investigation and optimization of their properties are important challenges in the field. Among the most promising “Cd-free” alternatives are indium phosphide (InP) NCs but despite all advances in their synthesis, there is still a need to achieve narrow fluorescence of such NCs – a parameter crucial for their applications in light-emitting devices (e.g. in displays).In this project, we propose a novel approach to solve this issue, which consists in the chemical synthesis of two-dimensional InP nanoplatelets (NPls). To achieve this, two strategies will be examined: recrystallization of small InP NCs and cation exchange. The research of the first strategy will involve studying precursor reactivity, searching for a suitable promoter of anisotropic growth, and on the optimization of the reaction conditions. The cation exchange strategy will focus on the investigation of the incorporation of indium ions into the pre-synthesized Cu3-xP NPls to achieve complete cation exchange. In the next stages, further work will concentrate on the optimization of obtained NPls for practical applications through achieving spectral tunability by alloying and through maximizing photoluminescence quantum yield and stability by covering InP NPls with a wide bandgap shell. Additionally, to demonstrate the application potential of the prepared NPls and related heterostruct
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'European Obesity Consortium studying the Hypothalamus and its Interaction with Peripheral organs', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The past decade has seen tremendous progress in our understanding of homeostatic regulators controlling energy balance. Insights from human and murine genetics have illuminated multiples pathways within the hypothalamus, brainstem and higher brain regions that play a key role in the control of food intake, whilst physiological studies focusing on the gastrointestinal tract have revealed a panoply of hormones that are secreted in response to or in anticipation of food intake and act centrally to regulate appetite. EurOCHIP brings together world leaders specializing in both areas in order to explore the interaction between the periphery and the brain in the control of energy homeostasis. Our programme of research will comprise four interdependent work-packages: i) characterising the interaction of gastrointestinal hormones with the hypothalamus and brainstem, with the aim of identifying novel molecules and pathways that mediate food intake; ii) using imaging techniques and behavioural phenotyping to explore the response of brain areas involved in higher cognitive and affective functions to these gastrointestinal hormones; iii) harnessing the power of human genetics to determine the role of sequence variation in and around newly identified candidate genes in appetitive behaviour and response to dietary interventions, focusing in particular on childhood obesity and iv) determining the effects of specific dietary interventions on gastrointestinal hormone secretion and using pharmacological studies in humans to mimic the hormonal milieu seen after a meal or bariatric surgery.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Smart, Multifunctional Dental Implants: A Solution for Peri-Implantitis and Bone Loss' to be submitted under Horizon 2020.

assistant: **Abstract**

At the moment, peri-implantitis remains an unsolved issue not only within EU but also worldwide, affecting up to 43% of the dental implants, with heavy smokers, patients with systemic health conditions (e.g. uncontrolled diabetes) and the immunosuppressed to be more vulnerable to the disease. Currently used dental implants are of low functionality and prone to bacterial colonisation and to the formation of bacterial biofilm.  I-SMarD aims to provide a proactive option for solving the outstanding condition, by delivering multifunctional dental implants which; i) can detect the changes of the surrounding microenvironment and respond by releasing agents (e.g. nanoparticles, antibiotics) to prevent bacterial colonisation; ii) will have the appropriate structure to match the anatomical characteristics of dental tissues and the components to promote the formation of implant/bone and implant/soft tissue interfaces; iii) will be coated with photoactive layers which will enable the non-invasive monitoring of the healing process (i.e. health of soft tissue) after surgery. With these we aim to prevent bacterial colonisation around dental implants and reduce the required time and cost of rehabilitation period for patients benefit. The addition of photo-active layers will impact on the diagnosis of peri-implantitis offering clinicians a diagnostic tool on live monitoring of tissue healing. For the fabrication, we will utilise advanced manufacturing techniques as 3D printing of titanium (Ti) and Ti alloy powders and Pulsed Laser Deposition for coating the surface of the implants. This will allow the delivery of complex, functional but at the same time low cost, personalised implants. Aim of our multidisciplinary team is not only the development of an advanced implant but also the del
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Slovenian Quantum Science Hub' (SQUASH).

assistant: **Concept**

Located in Ljubljana, Slovenia, the Jožef Stefan Institute is the national leader in quantum research. Supported by the Marie Skłodowska-Curie Actions programme, the SQUASH project – Slovenian Quantum Science Hub – will employ 40 foreign postdoctoral researchers. The fellowships are designed to advance their research skills in four multidisciplinary fields: quantum theory, quantum materials, quantum technology, and quantum computing & information. With a broad range of international and intersectoral secondments, as well as career-developing training programs, fellows will gain a blend of additional versatile skills, significantly boosting their career-growth opportunities. The project aims at developing skilled and innovative quantum workforce across research, technology, and academia to tackle the upcoming challenges of the second quantum revolution.


**Keywords:** quantum physics, quantum theory, quantum materials, quantum technology, quantum computing, quantum information
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Study and validation of the computing model for the atlas experiment' (ATLASCM).

assistant: **Concept**

The ATLAS experiment is a large detector for the study of high-energy proton-proton collisions at the Large Hadron Collider (LHC), presently under construction at the European Organization for Nuclear Research CERN and scheduled to start operation in 2007. In the ATLAS Computing Model, after reduction of the data by the online trigger processor farms, the volume of data recorded for offline reconstruction and analysis will be of the order of 1PB (1015 bytes) per year.The present proposal aims at a major contribution to the understanding, the development, the validation and the deployment of the ATLAS Computing Model that will be based on GRID technology. Part of the project will be to participate to the development of the software infrastructure needed for the production chain and the physics analysis. The conclusion of the work will be the demonstration of the full ATLAS data analysis chain in a large-scale GRID production infrastructure.The study and validation of the Computing Model started two years ago and will continue for few years in the context of the so-called Data Challenges (DC). DC1 was conducted during 2002-2003; the main achieved goals were to put in place the production infrastructure in a real worldwide collaborative effort and to gain a lot of experience in exercising an ATLAS wide production model. The analysis part of the general Computing Model was not exercised in DC1.The focus of DC2-3, planned for 2004-05, is on testing the Computing Model itself and most importantly the tier-0 part, which aims at the reconstruction of the events just after they come out of the data taking chain. It also include an analysis phase intended to test the distributed analysis parts of the Computing Model, the schedule of this phase is still under discussion since a LH