RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'International Conference on Postharvest Science' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Scientific research in the field of postharvest handling of fresh agricultural plant produce is the basis for the development of the international trade in fruits, vegetables and flowers. This high level Scientists Conference is part of the series of International conferences on this area held every 4 years and which began in 1988 in Belgium. Its objective is to bring to the scientific community the advances, which have been made in basic and applied research in the field. The 4 days of sessions are planned to cover 4 areas of research: molecular biology, physiology, pathology and technology of postharvest science.Areas which progress has been rapid since the last conference in new Zealand in 1996 include: The elucidation of the ethylene signal transduction pathway and methods of applications of antagonists of both ethylene biosynthesis and ethylene action. The use of controlled and modified atmosphere with unconventional atmospheres including oxygen higher than air. Reduction of the use of chemical pesticides by developing biological and physical means of pest control as well as by genetic engineering. Maintenance of commodity quality pastharvest. changes in vitamins and medical constituents of fresh produce and technologies to minimize these changes. The medicinal value of the antioxidant potential of fresh fruits and vegetables and how it can be manipulated. Special technologies to maintain quality in organic produce. All these topics and others will be covered in the conference.ftp://ftp.cordis.lu/pub/improving/docs/HPCF-1999-00203-1.pdf
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Sacrificial Thermoplastic Injection Moulding platform for manufacturing small and complex metal and ceramic components' to be submitted under Horizon 2020.

assistant: **Abstract**

AddiFab has developed the first sacrificial thermoplastic injection moulding platform to support the manufacturing of small/medium size, complex and traceable metal and ceramic components with high precison – STIM-MC. AddiFab’s innovative solution is the first to remove the costly and time-consuming gap between prototyping and commercialization ramp-up.This is only possible due to AddiFab’s proprietary material and process which uses printed objects as intermediary process tools (moulds). It runs in a single platform which integrates the automatic production and post-processing of moulds.With single-use moulds produced automatically, prototypes and components with mould-like quality can be launched for in-market validation and easily modified. Thus, the STIM-MC platform reduces development costs, mitigates the risks of product failure and increases process efficiency, while enabling wider benefits for the healthcare, consumer products and automobile industry through new cost-effective materials.Through the successful development and implementation of the STIM-MC project, AddiFab will be in a strong position to exploit the micro and powder injection moulding markets and enhance its profitability by the stream of the sales, with an expected cumulated revenue of €71 million, 5 years after project completion.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Clonal hematopoesis of indeterminate potential and degenerative aortic valve stenosis'.

assistant: **Innovation**

Degenerative aortic valve stenosis is the most common acquire heart valve disease and will continue to increase as a result of an aging population. There is currently no medical therapy established to halt progression of aortic stenosis and the only definitive treatment is aortic valve replacement either by surgery or transcatheter aortic valve replacement (TAVR). Without valve replacement, the 2 year mortality rate approximates 50 % once patients are symptomatic. Although a number of general risk factors have been described for developing calcified aortic valve disease, risk prediction for progression of CAVD to severe stenosis is still poor. We demonstrated that somatic mutations associated with expansion of hematopoietic cells (“clonal haematopoiesis“ (CH)) are associated with a poor prognosis of patients with aortic valve stenosis undergoing TAVR. This application aims to address the following major points. We will determine 1) how mutations in the most prevalent CH-driver gene DNMT3A may directly or indirectly affect the pathophysiological processes leading to aortic valve stenosis, and 2) which type of mutation is particularly involved in mediating the poor prognosis. 3) We will determine the impact of CH on the reversibility of cardiac fibrosis after successful replacement of the aortic valve, and 4) determine the relation of CH with senescence and inflammaging. We will use cutting edge single cell and omics technologies to decipher the pathophysiological effects in patient tissues and circulating blood samples and will explore the pathomechanisms induced by DNMT3A CH-driver mutation by assessing cellular communication processes in vitro.The discovery of relevant of immune system mediated complexities in the progression of aortic valve stenosis and consequent car
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Towards 0.7 Terahertz Silicon Germanium Heterojunction Bipolar Technology' (DOTSEVEN) targeting Seventh Framework.

assistant: **Abstract**

DOTSEVEN is a 3.5 year IP proposal for a very ambitious R&D project targeting the development of Silicon Germanium (SiGe) Heterojunction Bipolar Transistor (HBT) technologies with cut-off frequencies (fmax) of around 700 GHz. Special attention will be paid to clearly demonstrate the capabilities and benefits of this technology with benchmark circuits and advanced system applications in the 0.1 to 1 THz range like THz imaging and sensing, wireless Gb/s communications and millimeter-wave radar.For a given lithography node, HBTs provide much higher cut-off frequencies compared to CMOS transistors while offering higher power density and better analog performance. SiGe HBT technology and SiGe HBT enhanced CMOS (SiGe BiCMOS) are key enablers for demanding mm-wave systems requiring more than a few µWatts of RF output power (which limits the applicability of even very advanced CMOS) and also offer high integration levels at low cost which precludes expensive and less integrated III-V solutions.10 out of the 12 DOTSEVEN participants were already partnering in the predecessor FP7 project DOTFIVE which succeeded for the first time to push fmax of SiGe HBTs (at room temperature) into the 500 GHz region thus setting a new world-wide benchmark. Triggered by the impressive DOTFIVE results, several activities in the rest of the world already have started to catch up or even surpass our achievements.The main objective of the highly qualified and motivated DOTSEVEN consortium is therefore to significantly expand the successful work of DOTFIVE, to further strengthen Europe's leading edge position in SiGe HBT technology and modeling as well as SiGe enabled mm-wave applications and to stay significantly ahead of non-European competition. A powerful and success-proven consortium has been set
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Improving the performance of wood joinery through vacuum impregnation of wood primers and preservatives in a single treatment process' (PRIME), addressing dissemination and exploitation.

assistant: **Impact**

The project addresses the need to improve the performance and durability of wooden joinery in order to make it more commercially attractive as a long-term investment. Wood joinery is losing market share to products made from alternative materials at the expense of its environmental credentials. This project will make wood joinery in Europe more competitive by improving its stability and durability through a process of vacuum impregnation of the primer and preservative in single, treatment operation. This will be achieved in a three-stage experimental research programme, which will;a) develop the process through a selection of compatible products and process schedulesb) Verify its technical benefits andc) establish its commercial feasibility by establishing an experimental treatment plant. The research will lead to a better public image of wood joinery by improving performance resulting in significant decreases of on-site failures
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Transformative Impact Of BlocKchain tEchnologies iN Public Services' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

'TOKEN' aims at developing an experimental ecosystem to enable the adoption of Distributed Ledger Technologies (DLT) as a driver for the transformation of public services towards an open and collaborative government approach. During 32 months, a multidisciplinary consortium of 11 partners comprising (a) IT developers/RTOs with experience in development of blockchain components/IoT & Big data platforms (FBA, IMEC, VIL, CERTH, FIWARE), (b) blockchain associations (INF), (c) public administrations (AYTOSAN, KATERINI); (d) SSH experts in public management (UC) and (e) think tanks specialised in digital transformation & policy-making (DEMOS) and Open Commons business models (FBR) will develop a Blockchain Platform as a Service Solution (BCPaaS) to be tested in 4 highly replicable application areas that are common to many Public Governments across Europe: public funding distribution; management of public accounts; urban logistics; valorisation of data. BCPaaS implementation will be assessed from a multidimensional perspective (technological, cultural, socio-economic and legal impacts), paying special attention to attitudes shown by public servants, as key individuals in public service provision. BCPaaS architecture will endorse the Next Generation Internet values of trustworthiness, resilience and sustainability and keep the compliance of the privacy-by-design regulation principles as core driver. It will maximise interoperability potential with IoT & Big Data platforms as well as other blockchains. A specific business model, based on Open Commons principles and Distributed Governance, will be elaborated during the second half of the project, and project dissemination will pay specific attention to meaningfully engagement of +30 early adopters, firstly as members of TOKEN Obs
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Smart Maritime and Underwater Guardian'.

assistant: **Concept**

The primary goal of SMAUG is to improve the underwater detection of threats in ports and their entrance routes, by means of a integrated system capable of providing data concerning threat analysis between 3 main elements: ports security infrastructure, advanced underwater detection systems and surveillance vessels. Underwater detection and location will be performed by four primary methods:  i) acoustic detection, where a series of hydrophones will listen for sounds emitted by small underwater vehicles and will be processed by artificial intelligence methods, ii) rapid sonar hull scan, used to scan ships hulls and perform harbour floor scanning, iii) high resolution sonar inspection, to inspect objects in water with poor visibility and iv) collective autonomous location, where a swarm of autonomous underwater vehicles will act cooperatively. This will provide information to Artificial Intelligence modules which will improve the way detecting illicit and dangerous goods and/or of threats hidden below the water surface is currently done, taking into account sources such as Unmanned Surface Vehicle Systems, (USV), underswater remote operation vehicle (ROV), UAV (Aerial autonomous vehicle) and Port current information sources. The combination of these tools will allow SMAUG to prompt solutions capable of detecting possible threats to infrastructure or vessels, as well as identify vessels with concealed goods.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Sarcomeric-Simulation AppRoach in a COmputational Multiscale EnviRonmEnt' in the context of a Seventh Framework call.

assistant: **Objectives**

First, a simulation environment of the sarcomere will be developed by using lumped parameter models. This model will be incorporated into existing models of the cardiac contraction to eventually build a multi-scale model of the cardiovascular loop. At a later stage, this model will be coupled to local 3D models of cardiac devices. The study will focus on one specific application in cardiovascular engineering: valve closure force. Whilst forces of closure of prosthetic heart valves are an important characteristic with respect to the design, they are very difficult to quantify. Also, cavitation might be a problem, as could lead to catastrophic failure or blood damage. Closure lasts for only about 35 ms, and there are no adequate models that can predict or quantify the effect of local/cellular events of chemical, biochemical or mechano-electrical nature at the ventricular level on the closure forces. For potentially high-risk patients is possible that pharmacokinetical intervention may reduce the cavitation potential of the valve and risk of fracture. We propose to develop the first coherent multi-scale model of the system taking into account the cellular mechanisms of cardiac contraction, with feedback between electrochemical events in the vessel wall and detail haemodynamic characteristics of the flow
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'e-health tools to promote Equality in Quality of Life for childhood to young adulthood cancer patients, survivors and their families - a PanEuropean project supported by PanCare and Harmonic consortia'.

assistant: **Concept**

Cancer affects 35,000 children, adolescents and young adults (CAYAC) in Europe each year. Current 5-year survival rates are 80%, but the intensive oncological treatments leave CAYAC Survivors (CAYACS) at increased risk of cancer or treatment-induced late health effects, excess morbidity and mortality, and reduced quality of life (QoL). Follow-up care of survivors includes monitoring of cancers, managing all types of late effects, and maintaining overall health. It should also involve considering the needs of families whose functioning has been disrupted by cancer. There are several challenges providing follow-up care for CAYACS and their families: i) it is resource-demanding in an overburdened healthcare system, ii) psychosocial and supportive care needs are often unmet, and iii) access is inequal between European countries.The overall goal of e-QuoL is to use e-health tools to promote Equity in Quality of Life for CAYACS and their families. It will adapt an existing interoperable personalised e-Health tool that can be used alone or as an add-on module to existing tools such as digital survivorship care plans already used in several European countries. Through participatory research, involving CAYACS, families, associations, networks, health institutes, social sciences and humanities researchers and industrial partners from 15 different countries and backgrounds, we will i) identify the unmet needs of CAYAC families and survivors’ (including vulnerable groups: young age and cognitive impairments) and ii) adapt accessible and affordable tools to address these needs. These tools will provide a person-centred approach from medical follow-up, preventive behaviours (e.g. physical activity, nutrition), psychological and social support (e.g. education, employment) to related h
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Characterization of maternal microbiota-dependent imprinting of the neonatal immune system' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Humans live in a mutual beneficial relationship with the commensal microbiota that colonize the epithelial surfaces of the body. The remarkable impact of commensal microbiota on the mucosal and systemic immune system has become apparent during the last years. It is now believed that changes in the composition of the intestinal microbiota as a consequence of “Western” lifestyle, significantly contribute to the rising incidence of autoimmune and allergic diseases. There is evidence that exposure to certain microbes during early childhood or even to the maternal microflora in utero are important factors in shaping the health of the neonate/infant.The objective of this project is to understand the molecular mechanism into how signals originating from maternal microbiota can shape fetal and neonatal immunity. Using a model of transient colonization of pregnant mice kept under germ-free conditions, we have discovered a beneficial effect of maternal microbiota on the immune system of the offspring. Importantly, mice born from transiently colonized mothers exhibited higher numbers of innate lymphoid cell populations in the intestine compared to offspring from untreated germ-free mothers. We suggest two approaches to depict how and by which route the maternal microbiota calibrates the immune system of the offspring.Besides increased appearance of allergic diseases in children in developed countries, neonate and child mortality from infectious diseases are still very high in developing countries. Thus, the improvement of neonatal immunity is an important goal. Our research will contribute to the development of new therapeutic tools to reduce child mortality as well as for the prenatal prevention of chronic inflammatory and allergic diseases.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Weight reduction for safer, affordable passenger cars by using extra formable high strength austenitic steel', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

Lightweight, safe and affordable passenger cars reduce emissions and strengthen competitiveness of the European automotive industry. Therefore, the most promising materials are the optimized austenitic stainless steel grades EN 1.4301 and EN 1.4318 which have high strength and extra formability superior to new HSS, DP, TRIP, Al and Mg. The extensive use in modern cars has been limited by a lack of sufficient manufacturing knowledge. The present consortium of 9 partners from 6 EU countries including three car manufacturers will prove the materials potential and feasibility for crash relevant and chassis parts. Expected results are 40-50% weight reduction of replaced parts, passive safety increase, optimized manufacturing technologies and guidelines for mass production. The implementation of the results will be done during the project or latest 1-2 years after the project. The results will be extended to applications for rail and road transportation industry.