RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Nonlinear Panel Data Models: Heterogeneity, Identification and Estimation' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Unobserved heterogeneity is an important factor to take into account when making inference based on micro-data. In linear panel data models it is well known how to control for permanent unobserved heterogeneity in a robust way, i.e. without assuming any parametric distribution of the heterogeneity on the population. In contrast the problem is much more difficult in nonlinear models. A significant part of the research on microeconometrics in the recent years has been about dealing with this issue and many solutions have been proposed. A first objective of this proposal is to study how well the bias correction methods recently proposed work for other specific nonlinear models and data set of interest in applied econometrics. This will provide practitioners with reliable evidence about whether the methods work for the case they are interested in and which method is better among the many that have been proposed.  Unobserved heterogeneity in dynamic discrete choice models is usually only allowed through a specific constant individual term, as in linear panel data models. However, in nonlinear cases that assumption implies further strong restrictions in the model and previous explorations seems to indicate that we should allow for more heterogeneity. A second objective of this proposal is to analyze identification of a dynamic discrete choice panel model where not only the intercept but also the slope is heterogeneous. This will include to (i) see how much restrictions we have to impose on the distribution to point identify the model (or its parameters of interest) from a cross-section of a fixed periods; and (ii) study further the non-identified situations of that model by looking for partial identification. The interest on this is to know how much heterogeneity can be ident
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The role of cell type-specific timing in the robustness of development' (TIMERR) targeting Horizon Europe.

assistant: **Abstract**

Reproducibility in development is maintained via precisely-timed execution of gene regulatory programs required to build all cell types of the embryo. However, many perturbations challenge this robustness and accelerate developmental tempo, leading to increased phenotypic variability. Mechanisms underlying this century-old observation have been obscured by variation inherent to embryogenesis, but advances in statistical single-cell profiling have revealed an unappreciated source of variability: non-uniform progression of development across cell types. Here, I propose to use a combination of ultra-scalable single-cell genomics, cross-species alignment of developmental trajectories, and engineering of developmental rate to understand how cell type-specific timing differences influence reproducibility of development. First, comparing vertebrate species with natural tempo differences, fast-developing zebrafish (Danio rerio) and slow-developing medaka (Oryzias latipes), we aim to generate time-resolved single-cell transcriptomic profiles and map variation in cell type-specific timing. We will relate timing variation to a quantitative robustness measure derived from cell composition profiles for hundreds of embryos, asking how the tempo of development influences its ability to reproducibly build a well-proportioned animal. Second, we aim to identify cell type-specific drivers of timing and coordination. Specifically, we will modulate tempo embryo-wide and test for proportional timing changes across cells by tracking responses to perturbation at the cell type level. We will then use genetic tools to promote lineage-specific acceleration of development, assessing the embryo’s capacity to compensate for an induced asynchrony. In challenging coordinated developmental progression
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Orientational dynamics of liquid crystals studied with light' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

Research objectives and content The project combines the study of microscopic dynamics and microscopic dynamics of liquid crystals. Microscopic (molecular) dynamics will be studied with renowned (ultra-fast time-domain) techniques like Transient optical Kerr and Fluorescent depolarisation decay. The experiments will focus on biaxial smectic liquid crystal states. Multiple scattering of light will be developed as a new way to study macroscopic dynamics of liquid crystals. Furthermore multiple light scattering in liquid crystals is of fundamental interest because it allows to study anisotropic light diffusion. Training content(objective, benefit and expected impact) The hosting group has an extensive experience in the use of ultra-fast optical techniques in general, and in the field of liquid crystals in particular, which ensures an excellent training opportunity for the applicant in using these techniques. Above that, the project allows the applicant to apply his experience in multiple light scattering in the for him new field of liquid crystals, thereby broadening his horizon and acquiring fresh knowledge in the field of liquid crystals.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Modeling microgels: from microscopic design to macroscopic description' under Horizon 2020.

assistant: **Concept**

Soft matter provides the ideal playground for exploring physical phenomena that have no counterpart in atomic and molecular systems. A continuous progress in particle synthesis has provided a rich variety of soft, polymeric colloids, which are highly interpenetrable and can reach ultra-dense, jammed states. Such colloids offer exquisite control of material properties through a change in their internal architecture. Among this new generation of soft particles, microgels – colloidal-scale particles individually made by crosslinked polymer networks – have become a favourite model system for their responsive swelling properties and their multitude of applications. Notwithstanding their potentialities, knowledge of their behaviour from a fundamental point of view is still very limited. The present theoretical description is mostly based on simple models, which do not account for the internal, polymeric nature of the particles. Using state-of-the-art computational techniques across all scales (from atomistic to multi-blob coarse-graining), this 5-years work-program will provide an accurate model of both the microgels and of the effective interactions among them. The model will account for polymer/solvent interactions and for variation of the external control parameters at all densities, up to jamming conditions. In this way, I will develop a unified framework from the design at the molecular level of the individual particle up to the description of the macroscopic properties of the material. At all steps, I will verify my theoretical progress with experimental measurements performed by world-leading collaborators. This proposal will thus bring the current understanding of microgels to a new level: besides rationalizing existing results, it will open the way for new uses and a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Sustainable Intelligent Management of Indoor Air Quality for the Culture and Creative Industries' (SIMIACCI).

assistant: **Concept**

Climate transition is imposed to all sectors of the EU economy, including CCI, especially through more efficient use of resources. Amongst CCIs, Galleries, Libraries, Archives and Museums (GLAMs) require large quantities of energy for controlling Volatile Organic Compounds (VOCs), Nitrogen Oxides (NOx), Hydrogen Sulfide (H2S) and humidity for cultural heritage (CH) artifacts conservation due to the absence of smart and efficient Indoor Air Quality (IAQ) control technologies.SIMIACCI improves traditional IAQ solutions, such as CH storage/showcases conditioning, heating ventilation, and air conditioning (HVAC), by developing a portfolio of innovative solutions reducing related energy demand by 30-50%) and extent CH conservation time. SIMIACCI will demonstrate: i) Metal Organic Framework (MOFs) adsorbents to efficiently capture noxious VOCs; ii) MOFs to mitigate NOx in real scenarios; iii) MOFs to capture H2S, iv) Predictive modelling to forecast contaminants concentrations evolution coupled with monitoring sensors and conservation/maintenance recommendations; v) Modular designs that fulfil the technical and environmental requirements of controlling IAQ; vi) New business models for the solutions portfolio that integrate the developed pillars, supported by market analysis and economic, environmental and social sustainability analysis. By demonstrating first-of-a-kind energy- and resource-efficient solutions for strict IAQ management, CCI will inspire climate transition of 5 new sectors where transferability potential will be assessed and disseminated, including through the creation of the SIMIACCI label. Dedicated exhibitions, reaching 30,000 visitors, will consolidate GLAMs leadership for climate transition.SIMIACCI brings together world renowned academic materials and con
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Bringing the human being into the digital loop' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

In the era of the digital revolution, pushing the smart wearables to the forefront, bridging the gap between the human being and digital or other machines is the key of future applications. The existing technical solutions are still limited in their impact as they are unable to react to natural human behavior. The biggest disruptive digitizing step aims at detecting and interpreting directly individual behavior in conjunction with the situational environment – wherever, whenever, in whatever situation -, without the need of additional interactions with a device.Eye Tracking (ET) technology measures the eye activity to better understand sight, perception, reaction, and emotions, providing a complete bi-directional interaction with the environment. Existing head-worn ET solutions are only able to work in artificial, controlled lab environments.Viewpointsystem, based on its patented Eye Hyper Tracking (EHT) system, is the only company able to provide a solution that works under uncontrolled real-life environments.“Digital Iris” is the definitive tool to integrate the human being into the digital world. It represents a disruptive leap forward, providing total robustness, reliability and every-day-usability and allowing its use in professional applications whatever the conditions are. The disruptive leap is based on existing know-how, coming from the embedded gaze image processing previously used in the safety-critical automotive world by Viewpointsystem´s experts.Adding to a head worn, functionally robust EHT a robust Augmented Reality element, Digital Iris will generate real-time useful information based on users’ situational environment and reactions. This intuitive ‘Human Machine Interface’ will immerse the user into a complete digital loop, opening up complete new and d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Data driven implementation of hybrid nature based solutions for preventing and managing diffuse pollution from urban water runoff' (D4RUNOFF).

assistant: **Concept**

D4RUNOFF overall goal is to create a novel framework for preventing and managing diffuse pollution from urban water runoff through the data driven design of hybrid nature based solutions (NBS) adapted to the current and future risk scenarios solutions. This innovative approach will support water utilities, urban planners and policy makers in defining urban runoff and storm water management plans to enhance the quality of the water discharged to water bodies, considering the Climate Change.D4RUNOFF will have the following specific objectives (SO):- SO1 Increase the knowledge regarding urban runoff pollution sources and the impacts through the development of novel high-resolution suspect and screening & non target screening NTS methods for  Contaminants of Emerging Concern (CECs) detection and identification of the major CECs and relevant pollutantspresent in storm water source and assessing their fate in NBS- SO2 Development of  cost effective advanced online sensors for targeted CECs, metals and microplastics for improving the monitoring of the water pollution derived from urban runoff- SO3 Enhancing the implementation of advanced preventive and mitigation strategies to reduce diffuse pollution through the development of and innovative multiple-criteria decision analysis (MCDA) methodology integrated in Geographical Information System (GIS) for hybrid NBS design - SO4 Development of a risk assessment and mapping methodology to identify diffuse pollution hotspots for specific sites & considering climate change effects.- SO5 Development of an AI based platform to facilitate the development of effective urban runoff and storm water management plans based on informed decisions- SO6 Implementation and validation of D4RUNOFF approach in 3 case studies and 5 replication sites-
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Scalable spatial sensing and dynamic reconstruction of complex sound fields' (SONIFY) targeting Horizon Europe.

assistant: **Abstract**

SONIFY aims at developing the first ever unified theoretical and experimental framework to measure and characterize sound fields over extended three-dimensional domains, providing scalable audio sensing and delivering models that can synthesize virtual sound fields from experimental observations of the space. Classical measurement methods lead to an intractable problem: the number of measurements to characterize a sound field grows drastically with the size of the domain, and the sound field varies if the source moves, changes, or additional sources appear. In SONIFY, I conceive a ground-breaking approach to fully characterize an acoustic space from experimental observations, to predict or estimate any possible sound field in it. The key novelty lies in transforming how we characterize the propagation of sound in complex three-dimensional media: instead of modelling the observed sound pressure field directly, SONIFY focuses on modelling the propagation and underlying physical structure of the sound field. The research constitutes a novel framework that draws from acoustic holography, elementary wave models, deep learning and novel sensing approaches. The framework is scalable and enables to characterize sound fields over large domains (on the order of hundreds of cubic meters or more) and reduces the experimental costs by four orders of magnitude. SONIFY is set to deliver unprecedented sound field analysis and manipulation ability, leading to a seamless integration between real and synthesised sound. Ultimately, it brings about a new area that integrates experimental, virtual and computational methods in acoustics and audio. The framework also serves to tackle withstanding challenges in the field, and to address open scientific problems in disciplines concerned with the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Fully controlled RTM tooling and high deposition rate ALM technologies for cost-effective and sustainable manufacturing of hybrid laminar wing demonstrator' (HERON), addressing dissemination and exploitation.

assistant: **Impact**

The overall objective of HERON is to develop and manufacture a comprehensive set of innovative, cost-effective and sustainable tooling for RTM processes as well as the use of high deposition rate ALM technologies, aiming at improving the energy and resource efficiency of the manufacturing of a leading edge and trailing edge for integration on aeronautical demonstrator. To this end, four innovative technologies will be combined and demonstrated at operational environments in aeronautic sector reached TRL 6: A.Modular design for RTM tooling to facilitate leading edge parts demoulding and heating strategies, combining different heating systems in customized surfaces.  B.Near real time process monitoring as path to control RTM process parameters (such us temperature) relying on in-mould sensors (thermocouples, strain and pressure gauges), external gauges (thermal cameras) and a control algorithm for thermal distribution.  C.High deposition rate hybrid ALM for trailing edge production to reduce resources consumption, using resins specifically developed for aeronautical applications.D.Finally, a fully automated and high accuracy production environment for the manufacturing of the necessary tooling for the leading edge and the application of the ALM technologies for the trailing edge, could ensure an accurate integration on the hybrid laminar wing demonstrators and an easy reparation or modification of the RTM tooling and ALM partsThese four innovative approaches can lead up to a direct 25 % of energy consumption reduction, 20 % of cost reduction and 30 % reduction in time cycle for the production of aeronautical structures.The project concept will address 100% tooling needed in the RTM and ALM processes, both for manufacturing and validating purposes, leading to a reduction o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Kidney Nephron Orientation in Vivo-like in Vitro'.

assistant: **Innovation**

KNOVV aims at directing nephron spatial orientation within renal organoids to mimic in vivo kidney development.Chronic kidney disease (CKD) is an increasing socio-economic burden, with 100 million people affected in Europe; available treatments are limited to dialysis and transplants. Tissue engineering and regenerative medicine (TERM) aims at developing in vivo–like organs, using in vitro three-dimensional (3D) systems as new therapies. Promising TERM therapies involving self-organized renal organoids from human induced pluripotent stem cells (hiPSC) are being investigated. These kidney organoids contain the appropriate cells although heterogeneity, immature stage and lack of the spatially specific nephron orientation are still major bottlenecks. These limitations impair microphysiological form and function, which limits their research utility and clinical applications. I hypothesize that inducing spatial nephron orientation in kidney organoids will result in improved maturation and function closely mimicking the in vivo organ. To achieve this, I will optimize protocols to generate renal organoids from hiPSC. I will identify molecules to inhibit or induce glomerulogenesis (glomeruli formation), and develop glomerulogenesis-inducing and -inhibiting hydrogels for bioprinting renal organoids. Immunostaining, qPCR, and functional assays will be used to evaluate the morphology and function of the 3D bioprinted renal organoid construct.  KNOVV will strengthen my research and academic profiles, broaden my knowledge and experience by combining developmental biology, TERM and biofabrication to improve renal organoids. My ambition is that the bioprinted renal organoid constructs with spatially directed nephrons will enable unprecedented microphysiological maturation and function