RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Lifecycle extension of salvaged wooden materials through reuse in dowel-laminated timber'.

assistant: **Concept**

Reusing salvaged timber in new applications can make an important contribution to circular economy. However, currently the reuse of such materials is limited, especially in structural applications. One reason is the lack of demands from the wood sector due to the absence of standard grading procedures and other issues related to e.g., shape irregularities, service damages, dimensions limitation, and degraded properties, which will require costly, significant processing that makes salvaged timber less profitable. This project will demonstrate how a fit-for-purpose approach can be implemented in a practical manner to reuse salvaged timber in structural applications. The target application is in dowel-laminated timber (here: EcoDLT) floor panels. In EcoDLT, salvaged timber will be reused in combination with new (raw) timber using a new fabrication method that will not require significant processing or gluing. This can reduce the processing costs, which can make salvaged timber more profitable and more attractive for the wood sector. The project will first evaluate the current state of salvaged timber resources in Slovenia using resource inventory. A resource classification method will be then established using which the reusability and profitability of reusing each resource can be determined (objective 1). In the next stage, the concept and fabrication method of EcoDLT will be developed experimentally and its structural properties will be examined (objective 2). Analytical models will then be developed for predicting the structural properties of EcoDLT using a new ‘well-known weak points’ concept, which will consider certain strength-reducing features of salvaged timber that are not represented in the existing models (objective 3). The project will contribute substantially
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Innovative PROcurement for Visual Impaired People' (PRO4VIP), addressing dissemination and exploitation.

assistant: **Impact**

Taking into account the objectives of Vision 2020, the WHO's 2006 initiative for the elimination of avoidable blindness. When globally people with low vision are increasing as a result of the ageing of the world’s population. Where low vision not only affects the independence but has significant psychosocial and economic impact on the individual, the family and society.  Major consequences of vision impairment include a child’s ability to pursue education and an adult’s ability for high quality employment, risk of falls, difficulties with daily living and increased dependence. PRO4VIP project has the objectives of : (1) the creation of an European wide network of procurers (RITT, US, FVG, BFW, AQuAS); (2) the definition of a common innovation procurement roadmap in the short term and in the long term and (3) the definition of the public procurement of innovation procedure(s) that best meet(s) their needs (that could be either a Pre-Commercial Procurement (PCP) or a Public Procurement of Innovative Solutions (PPI) or both) and that in line with Vision 2020 would either support the early detection and the screening of functional low vision conditions or would support the provision for low vision services.This will be achieved through a staged process whose main steps are: (1) the identification of the shared procurement needs; (2) the analysis of the state of the art, the technologies available in the market and the existing patents; (3) the engagement in open dialogues with other procurers, end-users and suppliers; (4) the analysis of the different public procurement of innovation options; and (5) the definition of the selected procurement procedure(s).The consortium is an interdisciplinary team composed of procurers interested in the topic from different perspectives (H
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'THE GLUCO- AND MINERALO-CORTICOID PATHWAYS IN RETINA: MOLECULAR CARACTERISATION AND THERAPEUTIC IMPLICATION', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Considering the alarming rate of diabetic patients becoming blind after retinal edema formation, and the important risks of ocular complications due to the low specificity of the current glucocorticoid (GC) treatment, it is imperative to bring together all the necessary means for the development of novel therapies with better specificity, efficiency and limited secondary effects. To that end, it is crucial to fill the gap in the fundamental knowledge of diabetic macular edema (DME) physiopathology. By taking advantage of an existing beneficial but imperfect anti-edematous therapy (low specificity), we propose to use state-of-the-art methods to perform a wide and unique study on the mechanisms i) involved in diabetic retinopathy ii) and regulated by the corticosteroids, with the aim to potentiate the therapeutic effect of GCs, for a real restoration of vision in DME patients.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Analysis and definition of operational requirements for ATM' in the context of a Fourth Framework call.

assistant: **Objectives**

The ADORA study aims at the identification of ATM requirements and relevant constraints refining the definition of user requirements and their compilation into a user database. Applying feasibility criteria the ATM requirements and constrains will be compared against the user requirements.It will start with the collection of ATM requirements & constraints, utilizing work done at ICAO level , within European Community funded activities as well as Member States and EUROCONTROL (FANS,FEATS, ATLAS, AEGIS, PHARE, EATMS, etc.). Moving from these a check on their comprehensiveness is performed and a textual database will be produced.Then the definition of User Requirements phase will follow, mainly based on the EATMS User Requirement Document (URD), it will identify and complement airspace and non-airspace user requirements.The check on the preliminary adequacy of user/operational requirements, aiming at comparing user requirements with the proposed operational requirements will be performed and as a result a preliminary refinement of the EUROCONTROL ERAT Database will be produced.The Update Requirements activity will start after a six months time gap aimed at leading a number of reflections and discussions in the ATM community. It will gather the results of these debates.The Final adequacy of user/operational requirements will be the final step aiming at performing a comparison and fulfilment analysis and shortcoming assessment. %
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Oral culture, manuscript and print in early modern Italy, 1450-1700' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

From the palazzo to the piazza, from the church to the private household, the spoken and sung word had uniquely important roles to play in transmitting information, opinions and texts in the society of early modern Italy. Oral discussion and performance, both formal and informal, were used intensively in the culture of the literate minority, while the verbal culture of the uneducated depended mainly or solely on orality. Constant interaction between the oral and the written enriched and shaped both forms of expression. Yet the voices that were so prominent throughout the cultural life of this period have been neglected. This pioneering project will provide the first integrated study of the practices and the social, intellectual and aesthetic values of oral culture, thus opening up new horizons for the study of early modern Italian culture as a whole.The challenge is to recapture the rich but ephemeral world of Renaissance orality through correlated studies of the traces it has left in written sources such as diaries, archival records, literary texts, treatises and correspondence. The fundamental research question to be asked is: how did oral culture relate to written culture and how far was it independent of writing? The investigation will focus on four key areas: social performance, politics, religion and linguistic usage. It will encompass spaces such as courts, council chambers, churches, academies, streets, houses and the countryside; men and women of all social classes; and contexts including ceremonial and ritual events, oratory, public and private performance, and scripted and improvised entertainment. This unique research will also lead to a new understanding of the cultural functions of the exceptionally wide spectrum of languages used throughout the peninsula.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Dissemination of quality information technology to support the bid to manufacture process' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

This project demonstrates the application IT Tools and Methodologies for the re-engineering of the bid-to-manufacture process in manufacturing SMEs who are suppliers to the aerospace, automotive and defence industries. Such SMEs would typically be in a make-to-drawing specification environment.The objectives of the project are:- to demonstrate the impact and benefits of the use of IT Tools to improve and audit the effectiveness of the bid-to-manufacture process.- to disseminate and exploit the results of the project on a Europe-wide basis using industrial partners and regional technology transfer organizations.- to evaluate and assess the IT tools and the implementation using the ITAQUA methodology.The Demonstrator will include customer management, cost estimating and process planning, document management, ISO 9000 best practice and self-audit. This demonstrator is based in the following RTD projects:- EUREKA Famos Project EU630 (QMS - Quality Management Information System)- CRAFT Project CR-1097-91 (PIQPAC - Paperless ISO9000 Compatible Quality and Production Control System)- ESPRIT Project 6572 (ITAQUA - Information Technology applied to Quality)The consortium will develop the work undertaken by the Quality IT Working Group EP9812 and contribute directly to the Working Group's objectives.The project consists of three main phases:- implementation and documentation of projects in the industrial partners.- dissemination of case study reference results through public seminars, workshops and conferences with the industrial papers and a multi-media demonstration pack.- exploitation through regional technology transfer organisations, distribution channels and direct sales.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Embryonic Stem cell-based Novel Alternative Testing Strategies' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

ESNATS aims at developing a novel toxicity test platform based on embryonic stem cells (ESC), especially human ESC (hESC), to accelerate drug development, reduce R&D costs and propose a powerful alternative to animal tests (3 Rs).  ESNATS will address current drug-testing shortcomings: - testing takes place late in the development cycle - animal test systems bear the risk of non-prediction due to inter-species variation  - non-ESC assays rely on primary cells or cells of malignant origin that are hard-to-standardise and limited in regard to quantity, homogeneity and genetic diversity - existing assay systems based on primary animal cell lines do not reliably represent the physiological situation ESNATS will develop a battery of toxicity tests using hESC lines subjected to different standardised culture protocols. Tests will cover embryoid bodies in different developmental stages and differentiated derivatives including gamete and neuronal lineages, complemented with test systems for hepatic metabolism. Predictive toxicogenomics and proteomics markers will be identified. The individual tests will be integrated into an ""all-in-one"" test system. To enable future industrial use ESNATS will prepare automating and scaling up of hESC culture. The predictivity, quality and reproducibility of ESNATS will be evaluated in a proof of concept study. ESNATS benefits are to increase safety due to better predictivity of human test systems, to reduce, refine and replace animal tests, to lower testing cost, and to support medium/high throughput testing.  ESNATS objectives will be achieved in a 5 year multi-disciplinary collaboration of leading European researchers in alternative testing, toxicology, ESC research, genomics, modelling, and automation. The consortium will also include rep
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The Hidden Costs of Energy Conservation' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

Research objectives and content:The research project at CIRED aims to reassess the size of the no-regret potential i.e. the energy conservation potential available at a net benefit. It will do so by both establishing a modelling-oriented taxonomy for relevant hidden costs on the level of firms and of policy programmes as well as by performing empirical investigations. The innovative aspect is that it links research on barriers more closely to energy-economy models.The whole work programme will require 18 months and consists of the following work phases:A. Training in the data structure, input assumptions, interface problems and limits of the combined top-down/bottom-up model NEXUS-ImaclimB. Training in the basic construction, functions and problems of the models STARTS and DIAMC. Refinement of a taxonomy of hidden costs and of hypotheses on their determinantsD. Development of concepts for collection of empirical data on hidden costsE. Investigation of data (i.e. case studies, use of modelling data bases)F. Analysis and interpretation of data with respect to modelling implicationsTraining content (objective, benefit and expected impact)The applicant will be trained in selected energy-economy models, which will increase her specialist knowledge in the field of quantitative research on barriers to energy conservation and in the field of linking empirical research on barriers and hidden costs to such modelling approaches. Furthermore the research project at CIRED will allow important progress of K. Ostertag's ongoing PhD project on hidden costs of energy conservation.Links with industry / industrial relevance (22)The research project focuses on enterprises in the industrial sector as emitters of C0[2] and as decision makers. The perspective of industry on hidden costs and t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Suspended timber floor insulation project' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

In the UK, 6.2 million1 homes, in the Netherlands, 2.65 million2 homes built before the 1920s have uninsulated suspended timber floors, and based on our preliminary research across the EU (such as Belgium, NorthFrance, North-Germany) it is anticipated that further ~10 millions of homes have similar floor construction due the same climatic and ground-water conditions, resulting in a 18.3 million homes European market.Alongside wall and loft insulation - where significant traction has already been made across the European and global insulation market - floor insulation is essential for maintaining the thermal coherence of the property and eliminating unwanted draughts. Moreover, heat loss through floors accounts for up to 20-25%   of the total heat loss of older properties. Despite the above, floor insulation has not become widespread yet, which can be attributed to three major factors: i) householder resistance to disruption caused by floorboard and carpet removal; ii) the inability to crawl below the floorboards due to constrained floor depths in Europe; iii) high costs (£4,000 per property) and resultant long payback period (~25+ years).   Solution: To exploit this opportunity, SHS have developed a prototype design for a low cost, automated under floor insulation system (Ufloor) to i) eliminate structural disruption; ii) speed up the insulation process; iii) make suspended timber floor insulation accessible to the mass market. It achieves this by using a proprietary telescopic applicator (with an integrated camera for guiding movement) that can access the subfloor void through airbricks. Economic Impact: Successful deployment of Ufloor will enable SHS to provide a solution that is 60% cheaper, 5x faster and 80% less disruptive than incumbent methods, saving up to 2,900
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Mathematical Interfaces for Epidemiology and Environment' (MATINEE), addressing dissemination and exploitation.

assistant: **Impact**

This proposal would bring a mathematical epidemiologist from the U.S. to the University of Lyon (France) to collaborate with researchers in the Biometry and Evolutionary Biology Laboratory in research on the nosocomial transmission of rotavirus in pediatric and other hospital wards.  Because of inadequate sterilization and pathogen resistance to antibiotics, healthcare workers and hospital equipment act as vectors to spread these infections from one patient to another, causing thousands of deaths each year, especially among children under five years of age.  This project proposes to develop and analyze a sequence of mathematical models describing the transmission dynamics, beginning with deterministic compartmental models which describe the average spread of infections at the hospital level and progressing to stochastic and network-based models which take into account individual variations in transmission within small populations such as wards, and the structure of infectious contacts that connects multiple wards through workers and equipment moving from one ward to another.  The project also includes two methodological components: one which will compare epidemiological indices of infection transmission such as the basic reproductive number, to see which best capture the effects of contact structures (how potential infection events occur), and another which applies uncertainty and sensitivity analyses in order to derive a measure of confidence in the results.  This interdisciplinary collaboration, broad both in the fields of expertise from which it draws and in the spectrum of modeling approaches it uses, aims to play an important role in the context of public health: by putting predictive tools at the disposal of the community of physicians, it aligns with the public h
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Mechanism of transcriptional activation by pax-5 - bsap' to be submitted under Fourth Framework.

assistant: **Abstract**

Paired box-containing (PAX) genes code for a family of transcription factors which have been implicated in the regulation of morphogenesis and pattern formation. The B cell-specific transcription factor PAX-5 (BSAP) is a member of this family whose in vivo function has recently been investigated. It is, however, still unkown how PAX-5 activates transcription of its target genes.  The project will focus on possible interactions between PAX-5 and the basal transcription machinery, especially with TFIID (TBP), TFIIB and TFIIH. Mutations will be generated into PAX-5 that specifically block these interactions. The mutants will be assayed in a PAX-5-dependent in vitro transcription system and in PAX-5-deficient pro-B cells for their biological relevance. Further studies will include the isolation of other PAX-5- interacting proteins using a yeast two hybrid screen or a biochemical approach based on affinity-chromatography of nuclear extracts.