RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Mom matters: Expound the influence of the interaction between maternal 5-HTT genotype and maternal care on offspring’s individual neurodevelopment' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Serotonin plays a prominent role in a wide range of psychiatric disorders. Importantly, serotonin (5-HT) is not only a neurotransmitter but also a neurotrophic factor during brain development, contributing to neurodevelopmental disorders (NDDs). One largely neglected source of 5-HT affecting development is maternal serotonergic genotype, which can influence offspring through the placenta and by changing maternal care behaviour. As a pediatrician, I am interested in the latter, as it -unlike the biological route- can be modified, providing an opening for early intervention for children with NDDs. Here, I will delineate for the first time how maternal serotonin transporter (5-HTT) genotype affects maternal care behaviour and impacts offspring development from an individual perspective.To understand the influence of maternal 5-HTT genotype on offsprings development related to sex and genotype, I will use the well-established 5-HTT knockout (5-HTT-/-) rat modeling 5-HTT gene variance in humans and affecting maternal care. First, I will examine maternal care behaviours in wild-type and 5-HTT-/- mothers, and the developmental trajectories of male and female offspring with varying 5-HTT genotypes by tests assessing social and emotional behaviour from infancy to adulthood. Included are highly sophisticated analyzes of ultrasonic vocalizations, which I am an expert in. Second, I will elucidate the offsprings brain-wide neuronal activity pattern using cutting-edge brain clearing and 3D lightsheet microscopy. To test causality and provide a lead for an early intervention, I will determine if enrichment ameliorates maternal care and improves offspring development. This project is expected to uncover how mother genotype influences offspring development in the context of behaviours r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'The dynamics and evaluation of finger ponds in east african freshwater wetland ecotones using appropriate fish production techniques'.

assistant: **Objectives**

Riparian people of the Lake Victoria basin are vulnerable to reduced protein levels during the dry season. Hence, there is a need to enhance appropriate fish production and agriculture. Our multi-disciplinary project will develop and test, with local participation, an innovative, integrated agriculture/fish multicultural system - called finger ponds. This system uses semi-intensive aqua cultural techniques to enhance the natural productivity of wetlands and floodplains. The system will not harm the integrity of wetlands. Finger ponds are excavated at the landward edge of wetlands in the dry season, and fill during the flood cycle, thereby trapping fish as the flooding recedes. During the following dry season, the ponds are enriched with manure while the trapped fish grow and can be cropped. The land in between is cultivated with seasonal crops. Riparian communities with limited resources throughout Africa may benefit from the system.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Pan-European system with an efficient coordinated use of flexibilities for the integration of a large share of RES' (EU-SysFlex), addressing dissemination and exploitation.

assistant: **Impact**

The overall objective is to ensure an efficient and sufficient level of system services are provided to facilitate meeting world leading levels of RES-E while maintaining the level of resilience that consumers and society have come to expect from the European electricity system.This requires defining the right amount of flexibility and system services to support transmission system operators using a threefold approach.Firstly, the technical needs of the pan-European system will be defined for scenarios with more than 50% RES-E in will be identified and translated to services and products to be delivered in an enhanced market design.Secondly, the electricity market design and regulation needs to be augmented to efficiently and effectively procure the appropriate combination of these system services.Thirdly, implicit and explicit barriers to competitive forces being applied need to be removed. This requires an in-depth understanding of all stakeholders’ roles (Generation and flexibility providers, Transmission system operators (TSO) and Distribution System Operators (DSO) and regulators) at all system levels (interconnected system, national transmission and distribution sub-systems and consumers).For doing so, EU-SysFlex joins a multidisciplinary team of 34 partners from 14 European countries, led by the (Transmission System Operators) TSOs representing four different synchronous systems that integrate the pan-European interconnected electricity system: EirGrid & SONI (Ireland), PSE (Poland), AST (Latvia), Elering (Estonia), supported by the necessary (Distribution System Operators) DSOs, technology providers, and research & experienced entities. In addition, a group of three other European TSOs: Fingrid (Finland), LitGrid (Lithuania) and Ceps (Czech Republic), will join
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Hydraulic Stimulation Modeling in Geothermal Systems' in the context of a Seventh Framework call.

assistant: **Objectives**

The increasing demand for energy with the least possible environmental impact in the last years has led to an ever-increasing interest in geothermal energy world-wide. Most areas with elevated temperature gradients are hot but have a relatively low permeability. In such cases hydraulic stimulation is used to increase permeability and reservoir productivity.The aim of hydraulic stimulation is obviously the maximization of productivity. It is however linked to risks, such as induced microseismicity or borehole stability, which in turn are likely to increase significantly production costs. For the stimulation the pumping volume rate and the applied pressure are parameters influencing the reaction of the rock mass formation in the sense of brittle or ductile behavior. It is, as a result, necessary to develop methods of determining the exact stimulation procedure suitable in each specific case in order to enhance productivity, while keeping costs and risks to a minimum.The present project suggests an approach to the subject from three different aspects: constitutive, experimental and numerical. The constitutive model is to result from examination of the physics at the microscale and upscaling to the continuum by means of averaging techniques. Interaction of neighborinng cracks will be taken into consideration. As input  to the model the probability density functions of the orientations and spacings of cracks will be used. The output is to be the evolution of the fracture matrix and, as a consequence, the evolution of the rock permeability.The experimental program will focus on crack interaction and fracture propagation. The effect of high temperatures, as a rule present in geothermal reservoirs, will also be examined.The numerical program will follow two different paths, tha
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Fireball dynamics in relativistic and ultrarelativistic nuclear collisions' (FIRDYNCOL) targeting Sixth Framework.

assistant: **Abstract**

Relativistic and ultrarelativistic heavy-ion collisions provide the system where nuclear matter can be created and probed under extreme conditions. Studies of properties of the matter under such conditions are complicated because the fireball produced in s uch conditions evolves rapidly. The energy density is highest at the beginning of the fireball evolution, and this is the situation one ultimately wants to study. On the other hand, the observed distributions of hadrons reflect the state of the system at a later time when density is low and hadrons can decouple. The final state results from the dynamical evolution of the fireball. In order to identify signatures of any novel state of matter in hadronic observables, we must understand how different scenarios of fireball evolution would influence the observed data. This is the general focus of the proposed project: to achieve better theoretical understanding of fireball dynamics and its impact on hadronic observables. In the individual objectives we shall: con struct a new parametrisation of the freeze-out and make a global analysis of all spectra and HBT correlations; study the evolution of the pion phase-space density; investigate non-equilibrium mechanisms of flow formation and phase transition; study interfe rometric methods of source measurement (femtoscopy).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Advanced technological applications of nanocrystalline diamond/amorphous carbon composite films', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

Nanocrystalline diamond (NCD) films are expected to possess the superior properties of diamond combined with smooth surfaces and a low stress. The scientific objectives of the project include the investigation of the deposition, Characterisation and technological applications of NCD/a-C composite films. The films composed of NCD (with grain sizes up to 10nm) dispersed in an amorphous carbon matrix (a-C) will be prepared by microwave plasma chemical vapour deposition (MWCVD) and will be optimised concerning not only the crystallite size but also the nature of the matrix and especially regarding the combined effect of both components of the composite on the film properties for advanced applications. The obtained layers will be thoroughly investigated with respect to their basic (crystallite size, morphology, bonding structure of the matrix, composition of the matrix) and application relevant (deposition area, homogeneity, hardness, friction coefficient, stress, biocompatibility, etc.) properties. The possible applications of NCD/a-C films as wear resistant coatings for biomedical purposes and as a new material with extreme properties in micro-an nanostructure technology (for MEMS, AFM tips, membranes) will be evaluated. The training objectives of the proposal are closely related to the scientific ones and include gaining of knowledge for new deposition techniques, appropriate for preparation of advanced materials, for new analytical techniques, as a part of the extensive characterisation necessary for the thorough investigation of the materials and for testing of the functionalities of the materials with the application of multidisciplinary approaches, e.g. microtechnology, biological and chemical methods.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Mechanisms controlling gene regulation by nmda-receptor activation'.

assistant: **Concept**

Changes in gene expression is one mechanism by which neurons transform short-lasting electrical events into long-lasting adaptive changes that may underlie learning and memory.  Calcium (Ca2+) influx through the N-methyl-D-aspartate (NMDA) subtype o glutamate receptors and L-Type Ca2+-channels is the trigger for electrical activity-dependent transcriptional responses. To analyse the mechanisms controlling Ca2+-activated transcription, we are using the c-fos gene as a model system.  Analyses of the c-fos promoter lead to the identification of Ca2+ -responsive DNA regulatory elements. However, additional as yet unidentified control regions that lie within the transcribed region of the c-fos gene are necessary for Ca2+-dependent transcriptional activation  Aim of this proposal is the identification and characterisation of intragenic Ca2+ control elements.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Heterogeneously integrated Multi- material Photonic Chiplets for Neuromorphic Photonic Transfer Learning AI Engines'.

assistant: **Objectives**

HAETAE targets to establish a novel computing paradigm by developing a multi-material PIC technology platform and align this along photonic Neural Network architectures capable of operating along the principles of Transfer Learning methods. HAETAE will deploy a co-integrated PIC platform that brings together the best-in-class material platforms through micro-transfer-printing and hybrid multi-chiplet bonding and proceeds along the best-in-class linear optical circuit architectures, combining: a) Si/Si3N4/SiGe photonics for high-speed fan-in, weighting and fan-out computational stages, b) InP actives for on-chip amplification, and all-optical non-linearities, for speed- and SNR-enhancement in neuromorphic photonic circuit layouts, c) Si/Si3N4 non-volatile Micro-Electro-Mechanical Systems (MEMS) structures for energy-efficient and non-volatile weighting, d) embedded FPGA-based control plane for the efficient programmability of MEMS and chip-configuration. It aims to finally deliver  a Photonic Transfer Learning engine that can support one order of magnitude improvements along all critical performance metrics of AI chipsets: energy efficiency of <19fJ/MAC and on-chip computational power that can scale to ~4.1PMAC/s. HAETAE aims to highlight the versatility and flexibility of its twofold photonic transfer learning accelerator by targeting three discrete application sectors in communications and computing: i) real-time threat detection processor for DC cybersecurity applications, ii) DL and AI computing as a LLM transformer, and iii) an optics-enabled AI-enhanced DSP processor for IM/DD transceivers.


**Keywords:** photonic computing, photonic Neural Networks, neuromorphic photonics, multi-material integration, multi, chiplet integration, micro-transfer printing, silicon ph
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Biomakers of genotoxicity of urban air pollution: a dose-response study' in the context of a Fourth Framework call.

assistant: **Objectives**

The proposed project involves the investigation of the relationships between various markers of exposure to, early bioiogical effects of, and individual susceptibility to genotoxins present in the urban atmospheric air measured in human populations living in the city of Athens or in a nearby low-pollution area. The study has been designed with strict epidemiological criteria and aims to provide data on dose-response relationships which can be used for the setting of air quality guidelines and for risk assessment: a) Non-smoking volunteers (120 living in different areas of Athens with levels of air pollution ranging from moderate to among the highest in Europe and 80 living in or near Halkida, a low-pollution area 70 kilometers from Athens) will be studied. The size of the population groups has been determined using power calculations based on the results of a recent pilot study and is considered to allow sufficient statistical power to distinguish between the effects of different degrees of exposure. b) A battery of state-of-the-art biomarker assays will be employed, including measurements of external exposure to suspended particulates, their associated polycyclic aromatic hydrocarbons and NOx using personal monitors, urinary 1-hydroxypyrene (a measure of the internal dose of polycyclic aromatic hydrocarbons), DNA and protein adducts in lymphocytes, HPRT mutations, sister-chromatid exchanges and chromosome aberrations in lymphocytes, and polymorphisms in carcinogen activating and detoxifying genes as well as in rare Ha-ras alleles. The effects of seasonal variation will be examined by measuring all markers on each individual twice, once in the summer and once in the winter. In addition to biological and environmental monitoring, detailed information will be obtained fro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Revealing the structure and mechanism of mitotic chromosome folding inside the cell' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Mitosis is a fundamental biological process every cell undergoes at least once. It requires a dynamic and dramatic restructuring of the genome from extended interphase chromatin to compact individual mitotic chromosomes capable of faithful segregation. Altered nucleosome interactions, phase separation and loop extrusion have all been proposed to play important roles in shaping mitotic chromosomes. However, what the internal architecture of single mitotic chromosomes is, and how this architecture is established in space and time by different forces inside the cell remains unclear. This lack of knowledge precludes a comprehensive mechanistic understanding of mitotic chromosome folding and unfolding. This project aims to resolve the folding principles of chromosomes during mitotic compaction and decompaction in situ, in single human cells. To achieve this, we will combine newly developed nanoscale DNA tracing technology with quantitative single protein imaging approaches to achieve a systematic structural analysis of mitotic chromosome folding throughout mitosis. We will investigate when and where which structural features are first established, and then use targeted, acute perturbations to dissect which regulators are required to form and maintain them. The resulting data will provide an in situ structure-based model to explain the essential function of the genome in mitosis and will allow us to understand the spatio-temporal coordination of the underlying molecular and physical mechanisms. Overall, the proposed project will provide a new framework for understanding the physiological and pathological roles of mitotic chromosome restructuring during cell division.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Future INternet and Open Data EXpansion' (FINODEX), addressing dissemination and exploitation.

assistant: **Impact**

FINODEX is a project born to provide new economic and societal value to the European society, through the promotion and the support of innovative ICT services based on FI-PPP technologies and the massive reuse of open data while involving the SMEs and Web entrepreneurs on their creation. They will be able to take advantage of the availability of open data and FI-PPP technologies to create, in a fast and affordable way, innovative services able to bring a massive impact in society and under different domains: health, transport, environment, economy...FINODEX will offer five free different services to SMEs and entrepreneurs: FUND (€4.64M via 2 open calls following the called Lean Startup approach) SUPPORT (information about the open calls, technical and business support services) TEACH (tailored training on business planning and on technical requirements) CONNECT (with other FI-PPP initiatives, relevant stakeholders) INVEST (gathering private investors for the sustainability of the products/services created)For a SME or Web Entrepreneur is a unique opportunity to obtain funds and specialised assessment to create new businesses, products or services guided by a group of experienced partners: ZABALA in innovation management, TRISE in startup programmes and open data, CBS on business training tasks, ENG as technical expert on FI-PPP technologies, ASOLIF providing SMEs specialised on open source software and EUN as expert on private networks for investmentApplying the innovative Lean Startup methodology for new businesses generation, FINODEX will be able to provide services up to 100 different projects from all over Europe making use of the so-called funnel approach, where, from the initial 100 funded projects and after different stages and internal evaluations, around 20 wil