RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Personalized cardiopulmonary resuscitation device for emergency teams' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

Sudden cardiac arrest affects up to 1 million people in US and Europe per year, being the 3rd leading cause of death globally. Despite international medical efforts, 9 out of 10 people will die after a cardiac arrest (average survival rate 10.6%). In the European Union, cardiovascular disease costs to the economy more than €192 billion annually.Emergency teams suffer the most with the extremely high mortality and morbidity rates due to cardiac arrest worldwide. Currently, medical assistive devices play a limited role on teams’ diagnostics and therapeutic actions during rescue emergencies. Nevertheless, the defibrillation/CPR devices global market was valued at $1.7B in 2014 and is expected to grow until 2019 with a CAGR of 8% reflecting a strong market demand.pCPR is a portable, precise and personalized medical device to properly assist emergency teams during sudden cardiac arrest emergencies. It consists of a thoracic pad with sensors that doctors, nurses and paramedics apply directly to the patient linked to a new monitor display and defibrillator to support and guide their critical decision-making and patient-specific emergent therapy.The value proposition of pCPR is based on emergency end-users’ feedback and experts’ calls for action, through a lean fast-to-market strategy, delivering unique selling points: - Adaptive physiological feedback (disruptive innovation);- Focus on cerebral oxygen saturation, temperature and tcCO2 (new target indicators);- Clinical reasoning algorithms (cognitive aids at point of care);- Cardiac/Neurologic outcomes guidance (assisting device);- Data management for Quality control (analytics);- Exclusively non-invasive sensors (technology);pCPR wants to be one of the leading assistive device for emergency teams worldwide in a 5-years’ time
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for '100 MW Green hydrogen production in a replicable and scalable industrial hosting environment' in the context of a Horizon 2020 call.

assistant: **Objectives**

The objective of GreenHyScale is to pave the way for large scale deployment of electrolysis both onshore and offshore, in line with the EU hydrogen strategy and offshore renewable energy strategy.GreenHyScale will develop a novel multi-MW alkaline electrolyser platform with factory assembled and pre-tested modules, allowing rapid onsite installation capable of reaching a CAPEX below 400 EUR/kW by the end of the 5-year project. A 6 MW module fitting into a 40-foot container will be demonstrated as the first step in the project, and lead to a minimum 100 MW electrolysis plant located in the ideal hosting environment of GreenLab Skive: a symbiotic, industrial Power-to-X platform capable of replicating across Europe with associated green growth and job creation benefits.The minimum 100 MW electrolysis plant will generate green hydrogen for 2 years from 80 MW directly connected renewables in combination with certified green electricity from a TSO grid connection. GreenLab Skive distributes green electricity from both sources through its unique SymbiosisNet which optimises and exchanges energy in all forms (heat, gas, water, heat) between the industrial park entities and external suppliers and offtakers. The setup enables the electrolysis plant to reach an overall energy efficiency above 90%. The GreenHyScale electrolysis plant will become the world's largest electrolyser system qualified as a TSO balancing services provider, thereby reducing the cost of hydrogen to below 2.85 EUR/kg for an electricity cost of 40 EUR/MWh.Besides, because of the inevitable link between offshore wind and electrolysis, an upgraded high-pressure 7.5 MW electrolysis module suited for offshore applications will be developed.GreenHyScale will form new European green value chains that support the par
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Security Without Obscurity for Reliable Devices'.

assistant: **Innovation**

Cryptographic implementations are traditionally evaluated based on a trade-off between security and efficiency. However, when it comes to physical security against attacks exploiting side-channel leakages or fault insertions, this approach is limited by the difficulty to define the adversaries (e.g. their knowledge about the target implementation) and to specify sound physical assumptions. Quite naturally, the problem becomes even more challenging in contexts where implementations can be maliciously modified during design or fabrication via so-called hardware Trojans. To a large extent, these vulnerabilities echo the general challenge of restoring trust that is faced by cryptographic research in view of the recent Snowden revelations. In this context, we believe that the design of small components able to perform secure computations locally will be an important building block of future information systems. For this purpose, the SWORD project envisions a paradigm shift in embedded security, by adding trust as an essential element in the evaluation of physically secure objects. Our two main ingredients to reach this ambitious goal are a good separation between mathematics and physics, and improved transparency in security evaluations. That is, we want cryptographic implementations to rely on physical assumptions that can be empirically verified, in order to obtain sound security guarantees based on mathematical proofs or arguments. And we want to make the empirical verification of physical assumptions more transparent, by considering open source hardware and software. By allowing adversaries and evaluators to know implementation details, we expect to enable a better understanding of the fundamentals of physical security, therefore leading to improved security, efficiency
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'GENOMIC AND METABOLIC REGULATION OF METASTATIC CANCER STEM CELLS'.

assistant: **Objectives**

The major causes of cancer deaths are relapse and resistance to current therapies associated with the presence of cancer stem cells (CSCs) and metastatic growth in distant organs. CSCs have the ability to self-renew and differentiate in non-CSCs. In breast cancer, acquisition of stemness properties has been closely related to epithelial-mesenchymal transition (EMT), a key process in cancer invasion and metastasis triggered via Rho-ROCK mediated actomyosin contractility. Interestingly, in melanoma, transition from elongated-mesenchymal to amoeboid mode of movement (MAT) driven by Rho-ROCK signalling has been associated with increased stemness. Furthermore, preliminary data from host lab shows that actomyosin cytoskeletal regulates glutamine metabolism in both melanoma and breast cancer cells. Metabolic cues participate in stem cell self-renewal regulation, suggesting that, in very contractile cells, the regulation of EMT, metastatic spread and tumour initiation might be functionally linked to stemness via metabolic clues. Nevertheless, how very contractile cells regulate genes involved in all these processes remains unexplored. As increasing contractility via EMT in carcinoma cells or via MAT in melanoma cells correlates with increasing stemness, we hypothesize a molecular link between the pathways regulating both migration and stemness abilities, which will be maintained across tumour types (from carcinoma to melanoma). The main goal of this proposal is to understand how tumour cells can acquire stem cell traits to successfully metastasize and how this can be regulated by the actomyosin cytoskeletal by using an interdisciplinary approach that combines state-of-the-art techniques in molecular and cellular biology, biochemistry, in vivo imaging and animal models. This wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Cybercrime and cyberterrOrism (E)Uropean Research AGEnda' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The COuRAGE (Cybercrime and cyberterrOrism (E)UropeanResearch AGEnda ) consortium will deliver a measured, comprehensive, relevant research agenda for Cyber Crime and Cyber Terrorism (CC/CT) guided by the knowledge and experience of the highly experienced and exceptionally qualified consortium (16 partners, 11 countries) and Advisory Board members (14 organisations including EUROPOL, JRC and ERA). This Research Agenda will identify the major challenges, reveal research gaps, and will identify and recommend detailed practical research approaches to address these gaps through strategies that are aligned to real-world needs. These strategies will be supported by complex test and evaluation schemes. The purpose of COuRAGE is to significantly improve the security of citizens and critical infrastructures and support crime investigators.The COuRAGE approach builds on three pillars, namely:-a user centric methodology, to identify gaps, challenges and barriers based on real-world needs and experiences; an analytical and semantic approach, to deliver a taxonomy and create a common understanding of the subject with all stakeholders; and, a competitive and market oriented approach, to foster practical implementations of counter-measures using effective test and validation solutions. COuRAGE will obtaining accurate, robust and validated user requirements which will be reflected on the research agenda and improve the participation of citizens in the sharing of information and by sustained focus against cyber criminals and cyber-terrorist activities. This agenda will be elaborated through a progressive and collaborative approach, consolidating contributions from the legislative, law enforcement, research and industrial communities represented by the COuRAGE consortium and the COuRAGE
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Smart Card and Agent enabled Reliable Access'.

assistant: **Innovation**

Main ObjectiveSCARAB focuses on the synergy between smart card and agent technology in an open, distributed and secure service architecture. The project has the following main objectives:  -to evaluate, position and demonstrate the use of smart cards as a universal token for seamless access to a multitude of telecommunication services in an open service architecture,  -to verify the requirements for secure service access and information exchange through a distributed access control model,  -to identify the implications of agent based software development on mobility, security and reliability in and across heterogeneous network environments,  -to identify, define and demonstrate the potential of the synergy between smart cards and agents for reducing the complexity and diversity of user interfaces as implemented on a multitude of telecommunication terminals. Technical ApproachSCARAB will combine the assets of personalised control from a telecommunication terminal with the capabilities of smart cards on which agents can run to inter-operate in a secure way with service management components. To personalise a service to a specific user role, mobile code will be downloaded from a provider server to the smart card. This code will enable/disable particular capabilities of the terminal to which the smart card is associated and will provide the interaction procedures between the user and the service. The implementation of this mobile code in a network hosting distributed applications will be based on CORBA and will use plain Java. The intended software architecture will be implemented as a set of distributed agents that operate on top of an OMG-CORBA conformant Distributed Processing Environment (DPE). Information and computational models for a set of service components relatin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Cloud Storage for the Future' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Today's cloud market is dominated by three US hyperscalers, resulting in lock-in, high prices, and limited innovation. The BtrBlocks vision aims to tackle this technological weakness by developing low-level, cloud-independent infrastructure services that can be deployed on any cloud platform. Its first building block, CloudStore, is a next-generation storage service designed from the ground up for modern, high-performance SSDs. Unlike existing solutions, our design will drastically reduce the complexity of building cloud-native applications. By being cloud-independent, CloudStore will foster innovation and reduce reliance on hyperscalers. In the long term, CloudStore will serve as the foundation for a broader suite of BtrBlocks services, designed to simplify development of cloud services. This decoupling of hardware infrastructure from high-level services will significantly lower overall cloud costs, spur new development, and strengthen Europe's strategic autonomy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'A novel pharmaceutical treatment for nonalcoholic fatty liver disease' (NAFLDcure) under Horizon 2020.

assistant: **Objectives**

Development of anti-microRNA therapeutic for nonalcoholic fatty liver disease Nonalcoholic fatty liver disease (NAFLD) initiates with excessive accumulation of liver triglycerides and progresses to nonalcoholic steatohepatitis (NASH), cirrhosis and liver cancer while also modifying brain metabolism. However, NAFLD pathogenesis, the corresponding impact on the brain and the links between them, are poorly understood. In addition NAFLD is largely untreatable. We have discovered that excess microRNA (miR)-132 initiates NAFLD and that miR-132 suppression by oligonucleotide antisense treatment effectively reverses NAFLD in acquired and inherited mouse models. Here we  to develop this discovery as a novel and effective pharmaceutical for the treatment of NAFLD, a serious and widespread disease for which there is at present no pharmacological treatment.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Portable and disposable biosensor microarray based on FETs with a biofunctional gate to detect VOCs in breath'.

assistant: **Concept**

The growing interest in medicine in connecting different volatile organic compounds (VOCs) patterns in breath with diseases and disorders has increased the demand on breath tests devices. Nowadays, the required apparatus for breath analysis in the market a re bulky and difficult to operate and handle, they need a large amount of sample and several hours are needed to obtain a result. In addition, they are expensive (ranging from 600 to 25.000euro).Therefore, the project focus on developing a breath test dev ice which is fast, portable, extremely sensitive, with low cost and easy to miniaturize. The main challenge of the BIOFET project is the use of a tailor made biofunctional nanomaterial for gas-sensing purposes in a silicon micromachined array based on field effect transistors (FET). The biofunctional material consists in a coiled-coil peptide-based assembly of gold nanoparticles and it is possible to synthesize it using different types of peptides having the possibility of designing a more selective device.The transducer device, a silicon FET microarray, can provide a lot of key benefits for sensing target gases such as low fabrication costs and mass production (standard CMOS process), low power consumption, compact size, small weights, fast response (milliseconds) and the ability to readily integrate with signal conditioning electronics and other devices.The core of the multidisciplinary research project BIOFET converges on biological recognition mechanisms, nanosciences, materials research and techniques of analysis at a common research frontier. This innovative multidisciplinary technologically relevant research is crucial in forging strong links between industry and research as outlined in the Lisbon strategy and indeed throughout FP6.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Clinical validation of a bioMARKer for use in INtestinal PATHologies' under Horizon 2020.

assistant: **Concept**

MARKinPATH global innovation project aims at undertake the clinical validation of Xylose, after ingestion of Gaxilose, as a Biomarker of intestinal diseases. Currently, the measurement of Xylose after ingestion of Gaxilose is used to evaluate hypolactasia in adults. MARKinPATH is focused to improve the hypolactasia diagnosis; broaden the pathologies to monitor and to extend his use to paediatrics population. MARKinPATH will meet the demand of the EU on and innovation in healthcare, by enhancing diagnosis and management of intestinal pathologies. The resulting solution will also contribute to cost-effective and efficient health expenditure.Xylose-based, after ingestion of Gaxilose, biomarker improves technical features such as specificity and sensitivity with respect to the other tests available in regular clinical practice. Furthermore, alternative methods such as Hydrogen breath test (HBT) and the Lactose tolerance test (LTT) are invasive and have adverse effects that can be very annoying for the patient.Venter Pharma is a highly innovative SME with more than 11 years focused on advanced research, development and commercialization of clinical solutions in this field. Venter Pharma has a relevant Intellectual Capital and an extensive background in these technologies. MARKinPATH would suppose a massive-but-necessary growth and the consolidation of Venter Pharma in the pharmaceutical market.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Eradicating Poverty: Pathways towards achieving the Sustainable Development Goals' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Reducing absolute poverty and ending extreme poverty is at the top of the 17 sustainable development goals (SDGs) the member states of the European Union together with all other United Nation’s members agreed to work upon towards the year 2030. Since 1990, almost all developing countries have made considerable progress in reducing their population shares living below the poverty line. However, this progress was less dynamic in the 49 countries in Sub-Sahara Africa (SSA), where in 2017 out of a total population of 1 bn people 400 million still lived in absolute poverty. As poverty is a root cause for spreading instability and conflict the high numbers of the poor on its neighbouring continent is of special concern for the EU and the EU member states. In literature, there is somehow consensus that progress in poverty reduction may result from economic growth, from the implementation of social protection schemes and of minimum wages and from governance conditions, which influence a country’s performance in reducing poverty. Reviewing the literature shows that the academic debate on the determinants of poverty reduction takes place in disciplinary silos, that modelling and empirically analysing replicates approaches that work for high-income economies but ignores structural differences between high-income and developing countries, and that there is a large gap in understanding the determinants of poverty reduction. ADAPTED is a doctoral training framework that breaks the existing silos. It delivers high-level training with intersectoral relevance *in validating pathways towards poverty eradication, *in analysing interactions between poverty reduction and other policy areas, *and in optimising the impact of poverty reduction policies to early stage researchers to bridge the