RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Nano Packaging Technology for Interconnect and Heat Dissipation'.

assistant: **Objectives**

One of the major limitations to continued performance increases in the semiconductor and power electronics industries is integration density and thermal management. Continued transistor downscaling is quickly reaching its limits forcing a new focus on heterogeneous integration and 3D packaging technologies to continue performance improvements by reducing interconnect length between memory and multi-core logic. These efforts must combine high density electrical interconnects with low resistance thermal interfaces to remove heat from the intricate layered assemblies. Power electronics applications in hybrid vehicles and power supplies are also being pushed to new integration densities that are largely limited by the ability to transfer heat across interfaces to liquid coolers and heat sinks. Improved thermal management and integration densities for these applications will also be important to improve energy and manufacturing efficiency and component reliability.The proposed project aims at developing new technologies and materials for low thermal resistance interfaces and electrical interconnects by exploring systems such as carbon nanotubes, nanoparticles and nano-structured surfaces using different enhancing contact formation mechanisms combined with high volume compatible manufacturing technologies such as electro-spinning. Recent groundbreaking work on nested channel interfaces to control particle interactions during the formation of interfaces will be utilized to exploit the beneficial properties of the new materials. In addition, state-of-the-art modelling and simulation techniques with world class supercomputers will be combined with the development of experimental test structures to measure the performance of new interface technologies and validate design tools. F
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Novel strategies in mucosal adjuvant construction based on the immunomodulating properties of cholera toxin and iscoms', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

This shared-cost RTD project is highly innovative and builds on novel principles for immunomodulation using targeted actions directed at distinct cellular subsets of the immune system. The aim of the project is to acquire basic information about mechanisms in immunomodulation and to apply this information in the development of new vaccine adjuvants, which will allow the broader use of mucosal vaccines and in particular oral vaccines. Such vaccines are at present much warranted and with appropriate immunomodulation may be made highly cost-effective and safe vaccines. Although several probe antigens will be used for the evaluation of adjuvant efficacy in the present proposal a special focus will be given the prevention of H. pylori infection as evaluated in the murine vaccine model. Our approach to the construction of powerful mucosal vaccine adjuvants is unique. It is based on our accumulated knowledge of immune regulation and tolerance-induction at mucosal surfaces, our ambition to acquire detailed information on the mechanisms responsible for the mucosal adjuvant effects of cholera toxin (CT) and ISCOMS and, lastly, the ability to use this information in the construction of new non-toxic vaccine adjuvants. To achieve these goals we propose to: A) Compare the mucosal adjuvant effects of CT and iscoms for induction of local mucosal and systemic responses using conventional protein antigens. We will use various gene knockout mice to establish which are the regulatory requirements for the adjuvant effects of the two systems and based on these findings formulate strategies for the construction of novel mucosal adjuvants. Preliminary results have clearly indicated that CT and ISCOMS use separate pathways (and perhaps target cells) for the induction of immune responses follow
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Nano-scale and Artificial Materials for Adaptive Electromagnetic Wave Control'.

assistant: **Innovation**

This project will study the control of electromagnetic (EM) waves using exceptional materials, and the application of such to the design of novel adaptive guiding and radiating structures. Two classes of unusual ‘materials’ with similarities in terms of modelling method and potentials applications are concerned here, constituting two inter-related research lines (i) the nano-scale graphene material and (ii) artificial materials based on periodic structures.Concerning graphene, a first goal will be to derive simple yet efficient EM models for the monolayer atomic structure, derived from usual EM concepts and solid-state properties of graphene. Such modelling will be experimentally validated and then employed to the design of graphene-based devices, including wired and wireless intrachip interconnects and antennas. A very important aspect in this task is the tremendous potential of graphene for fully-integrated and effective device dynamic control, based on field-effect.In the case of artificial material made of periodic structures, they will be combined with MicroElectroMechanical Systems (MEMS) in order to achieve integrated EM devices with dynamic control capabilities. At the theoretical level, the properties of the periodic structures will be tailored to achieve unprecedented radiation capabilities (e.g. the total control of the radiated beam at all space directions).The frequency range of interest for these studies mainly concern millimeter-waves, but THz will also be considered in particular cases. Very importantly, both theoretical and experimental aspects will be carefully addressed. This ambition requires exceptional expertise and fabrication capabilities, which is available within the applicant team and host infrastructure and multidisciplinary activities. This
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Self-deployable Habitat for Extreme Environments' under Seventh Framework.

assistant: **Concept**

The main objective of the SHEE project is the exploration of an effective integration of architecture and robotics for space applications. The goal is to develop a robotically-deployable habitat design introducing generic principles which would help in defining main themes for further development of the standards for robotics integrated into the architecture regarding safety and for the development and design of larger robotic structures. Self-deployable autonomous habitats are needed in particular in extreme environments without infrastructure and heavy machinery.The SHEE type of habitat will provide significant background for further development and evolution of extra-terrestrial habitable structures and will provide a methodology and results that can be translated into more ""normal"" conditions, to achieving a more efficient, high-tech sector on earth.The final product will have a form of an example of a functional habitat for further testing and development. The concept is developed with a vision to correspond with an analogue testing habitat. The results of the SHEE project will be applicable in both space and terrestrial conditions, such as in extreme environments on Earth or during disaster mitigation.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Statistical and computational methods for the analysis of spatial data' under Fourth Framework.

assistant: **Concept**

The proposal covers a number of areas of spatial statistics, including There will be seven postdoctoral researchers, most if not all recent PhDs. geostatistical and lattice models, random point processes and stochastic We expect them to visit several centres and pursue joint research with different partners. The benefit to the researchers involved will be geometry problems such as deformable template models and tessellations. participation in a very vigorous area of statistical research with much Major areas of application include imaging, and the use of spatial and opportunity for subsequent employment in academia and in industry. spatial-temporal models in analysing environmental data. WE also consider models ?or spatial data based on mixtures. A common theme is the need for simulation-based methods of data analysis, in particular Markov chain Monte Carlo (MCMC) but also other techniques such as bootstrapping. This in turn leads us into theoretical analysis of MCMC and bootstrapping algorithms. A major theme of the proposed research is the development of original theoretical results for MCMC and bootstrap in the context of spatial models. A final theme is the study of extremal properties of spatial processes, motivated by a number of environmental applications.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Time and experience dependent evolution of hippocampal memory codes' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Following initial learning, information stored in memory undergoes a time- and experience-dependent evolution. Currently, the nature of this evolution at the neuronal ensemble level remains largely unknown. To obtain insight into this dynamic process there is a need to follow memory-associated neuronal representations in large populations of single cells over long periods of time. However, until recently it has been nearly technically impossible to obtain the requisite data. In my postdoctoral work I have developed an experimental system that enables such investigation by longitudinally imaging neuronal activity in more than 1,000 neurons simultaneously in the hippocampus of freely behaving rodents over the course of months. To enable high-speed imaging at cellular resolution in deep brain structures, my system combines four recent technical advances: (i) miniaturized head-mounted fluorescence microscopes for use in freely behaving mice; (ii) microendoscope probes, for high-resolution imaging of cells in deep brain structures pertinent to long-term memory; (iii) a chronic mouse preparation that permits longitudinal imaging over months of individual neurons lying deep in the brain; (iv) genetically encoded Ca2+ indicators to report neuronal activity. To investigate the principles of neural coding of long-term memory and their underlying biological mechanisms, my lab will combine this imaging methodology with genetic tools for manipulating neuronal activity in specific hippocampal cell types, and novel computational methods for analyzing data from large-scale neuronal populations. This proposal aims to determine how hippocampal place coding evolves as a function of learning and passage of time, and how adult neurogenesis shapes hippocampal information processing. Our resu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Transnational Digital Networks, Migration and Gender'.

assistant: **Innovation**

The project will explore two interrelated sociocultural dynamics that impact the future of European integration and have a profound effect on the development of a common European culture by challenging established ethnic, class, linguistic and gendered divisions. These are: a.  the rise in migrant mobility and the establishment of transnational migrant networks that enable the construction and negotiation of new forms of hybrid identity and a sense of multiple belonging based on the experiences of cultural diversity and intercultural communication, and b. the spread of transnational digital networks that transcend state boundaries and exclusive national identities and give users the potential to participate directly in processes of cultural production, exchange and consumption particularly through the use of new media technologies.  More specifically the project will address the question of participation of migrant individuals and groups in transnational digital networks by employing innovative methodologies combining online and offline research. Emphasis will be placed on the ability of migrants to access and produce diverse digital spaces and use them to promote their own needs and demands, but also in the possibilities for the promotion of intercultural dialogue and cooperation that open through the development of new interactive media.  Gender will be mainstreamed and treated as an integral aspect of the research design and analysis throughout the project. In particular, the project will explore theways in which changing gender power relations shape identities and performativities in transnational digital and migrant networks. In order to disseminate information and put the findings of the research into practice, the project will develop a transnational migrant digi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'New vaccination therapies for lung cancer' (LCVAC).

assistant: **Innovation**

The aim of this project is to develop new vaccination approaches for the highly needed treatment of lung cancer. Lung carcinoma is the number one killer amongst cancer patients, for which no adequate treatment exists. With conventional therapy, median survival for the subtype of small cell lung cancer (SCLC) is 15 months for limited-stage disease and 9 months for extensive-stage disease, whereas long-term survival is very low.Major obstacles to the successful treatment and eradication of lung cancer are late diagnosis, highly metastatic behaviour, resistance to chemotherapy and the impossibility to surgically remove all cancer cells. In principle, cancer vaccines are a most promising approach for the treatment of cancer in general and lung cancer in particular. Major obstacles in the development of a successful vaccine are the lack of cancer specific antigens to be targeted and the lack of tools to evaluate immunotherapy based on such targets.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Blockchain Platform to Track Chemicals along the Value Chain' (ChemChain) targeting Horizon 2020.

assistant: **Abstract**

As there is significant market demand for enhanced flow of data and transparency throughout the lifecycle of products, to comply with existing legisltive requirements and to address emerging circular economy challenges,ChemChain supports the industry by creating a trusted and globally accepted open-source blockchain infrastructure to store, exchange, build and track chemical-related information along the supply chain.ChemChain blockchain technology is a game-changer for decentralizing infrastructure and building a trust layer in the Chemicals Supply Chain. Every time a raw material or product changes hands, from manufacture to sale, its chemicals could be documented. This creates an immutable source of information on a product’s chemical components, allowing companies to overcome current supply chain constraints. Also, it dramatically reduces time delays, added costs, and human errors that plague the chemicals supply chain today.ChemChain leads to (i) reduction of costs and simplification of procedures for demonstrating regulatory compliance, (ii) enhanced exchange of information among companies and stimulation of new synergies, (iii) increased knowledge on chemicals in products also among consumers together with a better understanding of their importance and risks, (iv)facilitated access to information on chemicals in articles also to recyclers and waste operators to manage potential environmental and health risks, and (v) generation of big data on the flow of chemicals in the society as unprecedented knowhow needed to address upcoming sustainability and circular economy challenges.Business Opportunity: Since estimated average annual total direct compliance cost with the legislation relevant to chemical companies (Europe only) approaches €9.5 billion, our project has p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Strategic Predictions for Quantum Field Theories', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Ambitious Questions:*  How does the relatively calm macroscopic universe survive and emerge from the violent quantum fluctuations of its underlying microphysics? *  How do classical notions of space and time emerge from fundamental principles, and what governs their evolution? These questions are difficult to answer---perhaps impossible given current ideas and frameworks---but I believe a strategic path forward is to thoroughly understand the quantum predictions of our Yang-Mills and Gravity theories, and unambiguously identify their non-perturbative UV completions. The first step forward, and the goal of this project, is to move towards the trivialization of perturbative calculations.  Consider the notion of failure-point calculations -- calculations that push modern methods and world-class technologies to their breaking-point. Such calculations, for their very success, engender the chance of cultivating and exploiting previously unappreciated structure. In doing so, such calculations advance the state of the art forward to some degree, dependent on the class of the problems and nature of the solution. With scattering amplitude calculations, we battle against (naive) combinatorial complexity as we go either higher in order of quantum correction ( loop order ), or higher in number of external particles scattering (multiplicity), so our advances must be revolutionary to lift us forward.  Yet I and others have shown that the very complications of generalized gauge freedom promise a potential salvation at least as powerful as the complications that confront us. The potential reward is enormous, a rewriting of perturbative quantum field theory to make these principles manifest and calculation natural, an ambitious but now realistic goal. The path forward is optimized throug
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Economic growth and innovation in multicultural environments' (1998-2002).

assistant: **Concept**

The EU can be thought of as the biggest laboratory of intercultural collaboration of today's world. The process of enlargement and the immigration from outside EU will further increase the degree of diversity. It is a fundamental objective of this thematic network to provide to European researchers an interdisciplinary forum that studies the complex relationships between economic growth and innovation and cultural diversity. The working idea is that a useful approach to understand the costs and benefits of European diversity is to think of Europe as a potential reproduction on a world scale of some of the characteristics that urban centres have on a national and regional scale, given the high density of population and the variety of cultures represented. Using cities as a laboratory of diversity, a pattern of multidisciplinary workshops is proposed to assess likely costs and benefits associated with cultural diversity.