RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Climate Night Hamburg 2010' (CLIMATENIGHT2010) under Seventh Framework.

assistant: **Objectives**

Climate Night Hamburg 2010 consists of attracting all the categories of the public at large and bring them together with climate scientists at one location. After successful Climate Night 2009 with around 35.000 visitors during the night and more than 4 million people reached by the awareness campaign, the next version of Climate Night Hamburg shall mark the continuation of a well-adopted and entertaining concept in the City of Hamburg. The inauguration of world’s most important climate computer in December 2009 and the work of the KlimaCampus foster Hamburg to be the centre of excellence in the field of climate research.During the night scientists will guide all the activities organised and attendants will constantly be in direct contact with them, having the possibility of exchanging on any topic of their interest, linked or not to the job as researcher. Researchers are to be shown as ordinary people and the profession researcher as fundamental for the well-being of the society.  Visitors will be provided with multi-media based information about consequences of Climate Change and are encouraged to think about concrete actions preserving the natural environment. The Climate Conference in Copenhagen in December 2009 has shown that the topic needs more attention and a further discussion on a scientific level. The interest of the population for this phenomenon has increased and needs to be satisfied. Furthermore, researchers in the green technology sector can present their recent developments to combat Climate Change.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'EndoMapper: Real-time mapping from endoscopic video' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Endoscopes traversing body cavities such as the colon are routine in medical practice.  However, they lack any autonomy. An endoscope operating autonomously inside a living body would require, in real-time, the cartography of the regions where it is navigating, and its localization within the map. The goal of EndoMapper is to develop the fundamentals for real-time localization and mapping inside the human body, using only the video stream supplied by a standard monocular endoscope. In the short term, will bring to endoscopy live augmented reality, for example, to show to the surgeon the exact location of a tumour that was detected in a tomography, or to provide navigation instructions to reach the exact location where to perform a biopsy. In the longer term, deformable intracorporeal mapping and localization will become the basis for novel medical procedures that could include robotized autonomous interaction with the live tissue in minimally invasive surgery or automated drug delivery with millimetre accuracy.  Our objective is to research the fundamentals of non-rigid geometry methods to achieve, for the first time, mapping from GI endoscopies. We will combine three approaches to minimize the risk. Firstly, we will build a fully handcrafted EndoMapper approach based on existing state-of-the-art rigid pipelines. Overcoming the non-rigidity challenge will be achieved by the new non-rigid mathematical models for perspective cameras and tubular topology. Secondly, we will explore how to improve using machine learning. We propose to work on new deep learning models to compute matches along endoscopy sequences to feed them to a VSLAM algorithm where the non-rigid geometry is still hard-coded. We finally plan to attempt a more radical end-to-end deep learning approach, that
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Helical foldamers with tunable channels for transmembrane water and ion transport' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The development of synthetic molecules capable of mimicking the modes of action of biological ion and water membrane channels is crucial to understand their mechanism and potentially to cure diseases (channelopathies) associated with their malfunctions. Synthetic transporters and channels that have already been reported so far, suffer from ill-defined structures or complex mechanisms that make it difficult to establish structure-property relationships in order to improve their efficiency and selectivity. This project aims at designing, synthesizing and studying the very first membrane spanning unimolecular synthetic ion or water channels in the form of long helically folded aromatic oligomers with suitably oriented binding sites at the inner rim. It builds upon earlier achievements in aromatic foldamer design concerning both molecular recognition in helical cavities, and the development of efficient solid phase synthetic methods (SPS) to access sequences longer than 40 units. About 40 units are predicted to fold in a 10-turn open-ended helix with a sizeable channel, covering a total height of ~35 Å, which is equivalent to the thickness of a lipid membrane. Such objects would be structurally stable and well-defined, amenable to structural fine-tuning by changing the composition of individual monomers one at a time, to modulate channel diameter and polar/apolar features. Their channeling behavior will be studied in vesicles and planar bilayers and will be correlated to their structure. Such correlation will allow, for the first time in the field, to build predictive design capabilities. This multidisciplinary project will enrich my strong background on artificial membrane channels with foldamer chemistry and should be decisive to help me reaching an independent academic r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Reactivity of Aluminium Sulphate Minerals In Mine wastes (RASMIM)' (RASMIM), addressing dissemination and exploitation.

assistant: **Impact**

Mine wastes are unwanted, currently uneconomic materials found at or near mine sites. Volumetrically they are one of the largest waste streams in the European Community and also at a global scale and they often contain high concentrations of elements such as aluminium (Al) that can have severe effects on ecosystems and humans.The risks posed by exposure to Al are controlled by the reactivity of Al-bearing minerals, which in mine wastes are most commonly the sulphates alunite and basaluminite. In spite of their importance, their dissolution behavior and controls in mine waste environments are not well-known.The aim of the RASMIM project is to shed light on these issues for contributing to new mine development and to environmental and human health protection. With this goal, dissolution experiments using both natural and synthetic alunite and basaluminite will be carried out. The evolution of solids and solutions during dissolution will be monitored using a wide range of cutting-edge mineralogical and geochemical techniques. These observations will be complemented by the development of atomistic computer simulations for the same processes.The study will generate important data on the mechanisms, products and controls on the dissolution of these Al sulphates. The project will provide a better understanding of the relative roles on dissolution of factors such as mineral structure and impurities, surface area, solution pH, composition and temperature or secondary mineral formation, among others. On top of that, advances will be made in the understanding of alunite and basaluminite mineral structure and chemistry, their environmental stability and the behaviour of the potentially toxic element aluminium during dissolution. All these advances would contribute to bridge a key k
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Removal of heavy metal ions fro polluted water using MetaPure' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

MetaPure is a new bloremediation technology, based on a dried plant biomass, for the removal of heavy metals from (waste) water. The objectives of this research proposal concern the applications of MetaPure in the following real cases  Remediation of heavy metals from high salinity water solutions  Remediation of heavy metal from solutions containing a cocktail of heavy metals  Remediation of Mercury for recycling process The objectives will be achieved by:  Research of the biomass metal chemical binding groups and mechanism  Optimization of the filtration parameters  Optimization of incineration conditions of the biomass, for metal recovery
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'DEmocratic PARticipation in Territorial states' (DEPART), addressing dissemination and exploitation.

assistant: **Impact**

Who should have a right to participate in the making of political decisions? Political theorists have thus far approached this important moral question in two ways. Theorists of territorial rights argue that the right to make laws on particular territories belongs to groups, such that a person’s enfranchisement derives from her group membership. In contrast, democratic theorists argue that states should enfranchise anyone affected or subjected by their laws, regardless of group membership; if not, their lawmaking is undemocratic. This creates an intriguing dilemma. As they stand, the prominent theories preclude a straightforward dual commitment to democratic decision-making and collective territorial rights: we must either give non-members a say over a group’s lawmaking on ‘its’ territory, or withhold various individuals’ right to a democratic say.DEPART solves this impasse. It will conduct the first systematic exploration of how theories of territorial rights and democratic participation may be plausibly combined, and thus develop a unified theory of rights of democratic participation (through voting) in territorial states. The project will use what is known as the method of reflective equilibrium – a common methodology within the Anglo-American (or ‘analytical’) tradition of normative political theory/political philosophy.DEPART will achieve several valuable goals. First, by showing how insights from apparently disparate approaches may pull in the same direction, its unified theory gives a promising framework for fruitful future research on territorial rights and democratic participation. Second, it gives policy-guidance on several issues on the EU agenda, including whether EU citizens living in another member state should have a say in that state’s national elections
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Innovating Technology for Internal Reference of Solid State and Semi-Disposable Anitmony pH Catheters for Gastric Diagnoses'.

assistant: **Concept**

Research and Technical Develoment into Internal Reference of (ion-sensitive field effect transistor) ISFET solid State Glass and Semi-Disposable Animony pH Catheters. These devices are used for diagnoses of gastroesphageal reflux, titration of drugs and pre-and post -operative assessments. Glass and antimony pH catheter, gastric holter device, and semi-conductor technologies will be integrated and a comparative clinical study will be executed. The objective of this IRC research project will be systems that are timesaving, cost less (25%), produce more reliable data and secure diagnostics, has no cross contamination and eliminates the waste of Ag/Cl reference electrodes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'SUMOylation and kainate receptor synaptic plasticity' (SUMOKAINATE) under Seventh Framework.

assistant: **Objectives**

The aim of this work is to demonstrate the role of SUMO (Small Ubiquitin like MOdifier) in synaptic plasticity. Specifically, my goal is to show that synaptic kainate receptors (KARs) are regulated in an activity-dependent manner that involves their SUMOylation. Recently, Mellor and Henley have discovered that the KAR subunit GluR6 is a substrate for SUMO and that SUMOylation of GluR6 causes KARs to be endocytosed. This was demonstrated for synaptic KARs at mossy fibre synapses in the hippocampus, suggesting that it is a mechanism for activity-dependent regulation of KARs at this synapse. In the post-synaptic density, PDZ-domain-containing proteins play a prominent role in organizing synaptic elements. My hypothesis is that SUMOylation of GluR6 influences the interaction of KARs with PDZ binding proteins, thus leading to KAR plasticity. In addition, phosphorylation of GluR6 by protein kinase C (PKC) could potentially regulate SUMOylation itself. To test these hypotheses, I intend to employ electrophysiological techniques (patch-clamp recording) in acute and cultured thalamocortical and hippocampal slices, combining them with biochemical techniques to block specific protein-protein interactions and modulate the level of GluR6 SUMOylation. Since the role of SUMOylation is largely unknown outside of the nucleus, its involvement in synaptic plasticity constitutes a major new function for SUMO. Therefore, SUMOylation provides a novel and intriguing mechanism underlying synaptic plasticity.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'BreAking the Link betweeN myo10 and CancEr' (BALaNCE), addressing dissemination and exploitation.

assistant: **Impact**

Breast cancer is the most frequently diagnosed cancer form and the leading cause of death among women while pancreatic cancer is the fourth commonest cause of cancer-related mortality across the world and very difficult to treat due to its aggressive nature and the relative lack of curative options. A major impediment in the identification of new therapeutic targets lies in our limited understanding of the exact mechanisms taking place within the tumor microenvironment that are responsible for the development of cancer, progression and metastasis. Based on our recent experiments, we have found that high expression of an actin-binding protein correlates with poor clinical prognosis in breast and pancreatic cancer patients. Drawing upon our recent findings, the target of the PoC project is two-fold. First, to (i) validate the clinical application of our novel therapeutic concept by conducting a series of in-vitro and in-vivo tests on a set of 22 Myo10 inhibitory lead-compounds (i.e. “hits”) which were identified via High-Throughput Screening (HTS). Second, to (ii) take the necessary steps towards the definition of the best business path in view of the strong pre-commercialization potential.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Human interaction with large scale coastal morphological evolution (HUMOR)' under Fifth Framework.

assistant: **Concept**

The overall objective is to develop reliable assessment and forecasting techniques to better understand, model and predict the physical and geomorphological processes governing medium and long-term natural changes of the coastal zone, including the impact of anthropogenic activities. The emphasis here is on the role that large-scale morphological features play in long-term coastal evolution. Existing analysis and predictive tools will be extended and improved; data sets from different sources will be compiled and analysed in order to quantify the properties of key morphological parameters of large-scale features. These parameters will be used to calibrate the tools derived from physical considerations and to assess the morpho-dynamics of large-scale features. Results will be used to address common coastal and harbour management questions, looking for long-term economic and environmentally viable integrated management strategies, which will be applied to a single cell.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Collective Approach of Research and Innovation for Sustainable Development in Highland' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The HIGHLANDS’ goal is to contribute to Inclusive Sustainable Development in Highlands (ISDH) through collective and impact-driven Research & Innovation (R&I), based on capacity building, sharing of local-global knowledge, experience, and tools. It will drive a co-innovation process through secondments and research and innovative sessions (R&IS) involving public/private and non-academic partners, to build a shared vision of ISDH, enhance the capacities of researchers, managers, users, policymakers, thus bridging the gap between research and development. Our activities will be organized in 5 integrated work packages (WP): Coordination & management (WP1); Methodology & capacity building for ISDH  (WP2); Analysis, comparison and modelling of ISDH (WP3); Building a multi-actor ISDH Decision-Support Platform (DSP) (WP4); Communication, Dissemination & Exploitation of results (WP5). HIGHLANDS is supported by a network of 43 institutions including 31 partners from Europe (~35% non-academic), and skilled and motivated female and male researchers and local stakeholders. The work plan will run 8 successive R&IS (5 in Europe, 3 outside) to promote the exchange among participants as a foundation for innovation. Each R&IS will build upon collective learning principles and a holistic systemic approach, exposing participants to a wide range of world views that will encourage experimentation with practice. Each R&IS will focus on a particular aspect of sustainable highland development and will include collective learning, collaborative research, and capacity-building on data collection/analysis, modeling. To complement the R&IS, long-term secondments will be implemented for researchers and practitioners to deeply train and work together on specific issues identified by the consortium.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'ENRICH in Africa - A Multi-sided Platform Business Model for supporting the EU-African Innovation Community.' (EiA), addressing dissemination and exploitation.

assistant: **Impact**

The European Commission is aiming to extend the network of the ENRICH centres in USA, Brazil and China to cover other regions, in order to connect European researchers and entrepreneurs globally. The ENRICH in Africa (EiA) project is addressing this challenge by establishing the EiA Centre, targeting the sub-Saharan African region. Focus of the activities will be the set-up of a network of incubators and accelerators to deliver services to European and African innovators.To best deliver this model, the EiA consortium brings together active innovation ecosystem actors from across the EU and Africa, who, together, have co-created a business model that offers them, as customers, what they need; a strong value proposition and beneficial services. This foundation offers a strong revenue model that can ensure a legacy for the commitment provided by the European Commission through this grant. Utilising this co-creation ethos EiA brings together incubators and accelerators across the EU and Africa to act as Champions for EiA. The network, in the beginning comprising of EiA consortium members, will be expanded to other entrepreneurial support organisations that meet the EiA standards. Key element of the concept is the focus on capacity building and learning for incubators and accelerators in order for them be able to offer high quality services to innovators. The EiA multi-sided platform, with a clever digital backbone, will be the central point for all EiA activities, offering different services for a wide range of stakeholders in the EU-Africa innovation ecosystem.This project offers a testable framework, which will be piloted in the initial stage of the project timeframe, leading into an evaluation and subsequent centre implementation phase, which will see the roll out of the