RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Brain training tools for better focus - using games and brainwaves to improve performance in children with ADHD' to be submitted under Horizon 2020.

assistant: **Abstract**

Cortechs is addressing an exponentially growing brain-based health challenge impacting over 2 billion people and 1 in 9 children worldwide: the inability to reach the basic cognitive skill levels needed to maintain the attention needed for school, work, home and life.   Cortechs create data-driven, therapeutic games that improve attention levels in children. ADHD is expensive, it causes suffering and it impairs social and lifelong productivity for the child and their family. Each task a child partakes in needs their full attention to be performed successfully. While this statement may seem obvious, the reality is that current EU-wide approaches to treat these symptoms come at extortionate costs (trillions pa) to the European health and welfare systems with medication alone not tackling the core, cognitive skills affected in ADHD.    Our intervention provides games which can be played using your brainwaves on smart devices. Progress data can be remotely assessed by specialist clinicians to prescribe and amend individual therapies on secure web dashboards. Cortechs neurofeedback platform and gaming delivery system is a highly innovative, consumer facing solution in the cognitive healthcare market for ADHD.     Therapeutics in cognitive impairments (CI) is a high-volume market valued at €80 billion and will grow to €393 billion market by 2022. Our Cortechs enterprise platform (called Cerebrill) applies key evidence-based ADHD treatments in an end-to-end digital solution with access to easy-to-use, engaging smart brainwave games to improve their behaviours. The solution is device agnostic, cheaper and accessible anywhere with prescriptives remotely and securely controlled and moderated by clinicians.     This proposal would enable Cerebrill to be speedily commercialised to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Weight metrology and its economic and social impact on Bronze Age Europe, West and South Asia' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

This project explores the economical and societal transformations provoked by weights and measures during the Bronze Age in Western Eurasia. The impact and significance of weight-based measures for value assessments during the Bronze Age is largely unknown und understudied. My objective is to unravel this empirical and intellectual gap in studies of the prehistoric and ancient economy. The project will uncover new sources for the reconstruction of trade and exchange networks due to the identification of a mostly overlooked or ignored class of artefacts: early balance weights. This opens up a new understanding of the nature and extent of the earliest commercial economies in the world. The ambitious project aims to document for the first time potential weights, often of unexpected simple shape, as well as canonical weights, frequently not sufficiently documented in a selection of cases studies between the Atlantic and the Indus. Further focus will be on potential mass-related finished metal objects, standardization and pre-coinage currencies, contributing to the debate on the origins of money. Specific statistical methods and 3D scanning provide a novel tool package to verify assumptions in a rigorous way. Hypotheses to be tested include identifying the potential correlation of the emergence of weight metrology to elucidating the first extensive trade in raw material (like silver, tin), the connection of weights to other administrative and commercial tools like seals and script, and their impact of early conceptions of value. The early dissemination of weights and weighing systems will be analysed systematically on evidence from the Bronze Age in Western Eurasia. The proposed research starts with identifying and documenting potential balance weights and mass related objec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'C-H Acids for Organic Synthesis'.

assistant: **Objectives**

Enantioselective Brønsted acid organocatalysis has the potential to revolutionize asymmetric synthesis. However, the commonly used chiral phosphoric acid catalysts are typically limited to certain, fairly reactive substrate classes such as imines. Recently, more active and stereoselective catalysts have been introduced, which rely on acidic N–H bonds, and which have significantly widened the scope of suitable substrates. Despite the considerable success of these catalysts, however, several important and highly attractive substrate classes still remain out of reach. The applicant’s group has now identified C–H acids as novel and highly promising candidates to tackle these long standing challenges. Here, a research program with three major goals is proposed: 1) broadly conceived synthetic studies will be undertaken, which are expected to give access to C–H acids with a wide range of acidity and steric confinement. 2) These C–H acids will be applied to address one of the most general limitations currently encountered in organocatalysis: The enantioselective conversion of small and unbiased substrates. 3) The developed C–H acids, which are expected to enable unprecedented acidities and catalytic activities, will be employed in the activation of increasingly less reactive electrophiles, for example aliphatic aldehydes but also esters and olefins, for which enantioselective organocatalytic reactions are currently very limited or even unknown. Overall, this research program will aim at the design, synthesis and application of C–H acids as platform for solving several long standing challenges in asymmetric organocatalysis. The introduction of C–H acids for organic synthesis is expected to enrich the toolbox of synthetic chemists in both academic and industrial laboratories.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Investigating idiolectal performance: towards a methodology of forensic authorship attribution', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

The proposal will provide empirical data to be used in the creation of a methodological model for forensic authorship attribution. The data will be used1) to identify individual stylistic features invariant over time and independent of interaction topic,2) to describe patterns of idiolectal performance over time within a homogeneous group of informants, And3) to identify relevant implications for forensic authorship attribution.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Transgenerational transmission of maternal childhood trauma and its sequelae – Altered maternal physiology during pregnancy and implications for newborn neurodevelopment' (TransCTNeurodev).

assistant: **Concept**

Alarming statistics in a recent report by the EU Agency for Fundamental Rights suggest that 1 in 3 women have experienced physical or sexual violence in childhood. The sequelae of childhood trauma (CT) exposure include psychopathology, altered stress physiology, obesity, and increased likelihood of exposure to violence in adulthood. Also, emerging evidence suggests the long shadow cast by CT may be transmitted to the offspring of exposed individuals, who have a higher prevalence of psychiatric disorders. To date, potential pathways of transgenerational transmission have focused on the offspring’s exposure to unfavorable conditions in postnatal life (i.e., suboptimal parenting behaviors). However, it is likely that transgenerational transmission of the effects of maternal CT may start during fetal life. It is well established that CT produces endocrine and immunological dysregulation, and the persistence of such dysregulation during pregnancy may affect fetal brain development to confer increased risk for psychopathology. Despite its plausibility, fetal programming has not yet been studied as a potential transmission pathway of the effects of CT from mother to child. In this proposed prospective, longitudinal study, 200 mother-child dyads will be followed from early gestation till the neonatal period. Serial measures of stress-related endocrine (CRH, cortisol) and immune (CRP, IL-6) biology will be collected in early, mid and late gestation. At birth newborn MRI scans will be acquired to quantify volumes and connectivity of fronto-limbic brain regions. The proposed study will address specific hypotheses about the transgenerational transmission during gestation of the effects of maternal CT on her child’s brain and the role of maternal-placental-fetal endocrine and immune
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Faces behind Science' (FACE2FACE).

assistant: **Innovation**

To meet the objectives of the Researchers Night 2006, the following six types of activities will be organized on 22nd of September in the frame of the 10th edition of the Warsaw Science Festival:- A professor with a group of his/her young co-workers will perform a fragment of their basic research, with the active participation of the public. This should show the subject and character of a working day of the researcher.- A professor and his/her assistant will prepare various demonstrations accompanying academic lectures in experimental physics, with the active participation of groups of visitors. This should show the educational aspects of the researcher's profession.- A researcher in the field of applied sciences will present examples of her/his activity. This should show, that behind many public services there exists science and scientists.- Young researchers - why they do it, in spite of their bad financial situation in Poland?- Visitors are invited by researchers to science cafes to meet and discuss pre-selected, also controversial topics. The results of scientific research, the potential benefit and limitations, should be understood by all of us. We must also confront the possible dangers which may result from their improper use.- Special programs dedicated to two selected groups (journalists and school teachers) showing faces and passion of researchers.Both groups are crucial in creating a better environment for researchers within the society. In addition to scientific activity each of the researchers will also present personal interests and hobbies. The Internet Festival Newsletter and Academic Radio will present short interviews with researchers participating in this event.Forms: workshops, demonstrations, scientific cafes, Internet Festival Newsletter, radio pro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Boat Management', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

After years of focusing on products quality, pleasure boat builders have realized the need to emphasize the after-sales market and their customers’ demands for products that are both easy in upkeep and environmentally friendly. Concepts of Product Lifecycle Management and Intelligent Maintenance can be applied to fulfil such requirements and solutions are available in comparable sectors such as the automotive or ship-building areas. However, these concepts have yet to be applied to the boat sector. BOMA intends to close that gap for the benefit of Europe’s generally small and medium boat building enterprises. BOMA is driven by the commercial needs of these SMEs and aims to increase their international competitively by establishing Intelligent Products and Service Extensions for the marine sector. BOMA will benefit not only the boat manufacturers and their immediate customers, but the entire value network consisting boat designers, ship yards, charterers, component suppliers and marinas. The boat market cannot be underestimated – with pleasure marine industry revenues in Europe totalling in excess of €23 billion, BOMA aims to support a very significant market for innovative European SMEs. The BOMA consortium is driven by leading European boat manufacturers supported by leading research and industrial partners in the fields of Product Lifecycle Management and Intelligent Products. BOMA will develop services addressing Intelligent Maintenance, Sustainability, Upgrades and the used boat market. These services improve all phases of the pleasure boat lifecycle – from enhancing design processes with knowledge from the entire lifecycle, through the usage phase applying Intelligent Maintenance concepts and technologies to improve safety, reliability and quality to the end-of-lif
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Testbed for music and acoustics'.

assistant: **Concept**

The objective of the project is to provide a cost effective basis for multimedia and virtual reality technologies in the audio sector. The project is motivated by the need to provide user friendly creative tools for sound design and interactive music performance. These tools must be extensible and adaptive and have user interfaces accessible to multimedia designers or users, rather than to computer specialists. In order to achieve this, solutions must be developed for integrating low level real time signal processing components with high level user interface software components.The goal of the project is to be achieved by integrating research in three key areas of multimedia systems:- open distributed processing enabling cost effective and extensible high performance systems.- object oriented, portable design environments for rapid development and flexible reconfiguration of audio tools.- new multiparametric user interfaces and graphic display methodsThree subtasks are defined corresponding to the above research areas:Sound Processing Network: Sound generation and processing algorithms will be implemented for real time execution with the MIDAS protocol for open distributed processing developed at York University. The initial target will be a PC network. Porting of code to different processor types will be demonstrated and implementation studies on UNIX Workstations connected via ATM will be included.User interface design environment: An incremental, portable programming and sound design environment will be implemented with object oriented tools (Smalltalk80 and/or Java). Graphical tools for representing and defining sound processing and sound structure generation algorithms will be programmed within this environment. Multithreading and low level communication protocols
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Vaccine safety and immunogenicity signatures of human responses to VSV-ZEBOV – Sofia ref.: 115842' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The proposal, VSV-EBOVAC, directly addresses the topic 1 of the IMI2 call on Ebola by supporting the clinical development of a highly promising new Ebola vaccine candidate, the vesicular stomatitis virus (VSV)‐ vectored Zaire Ebola vaccine (VSV-ZEBOV). In non-human primates, a single dose of VSV-ZEBOV elicited a strong (100%) and long-lasting protective efficacy against Ebola Zaire infections. Developed by Public Health Canada and manufactured by NewLink Genetics, VSV-ZEBOV was thus selected by the World Health Organization (WHO) as one of the 2 most promising vaccine candidates. To accelerate its clinical development, the WHO has organized a consortium and supported the organization of parallel first-in-man Phase I/II clinical trials, both in Europe and Africa. The primary objectives of these trials, initiated mid-November 2014, are to study the safety and antibody-inducing capacity of various doses of VSV-ZEBOV in European and African populations.We propose to build upon this asset to acquire new and critical knowledge of the innate and adaptive immune responses elicited in humans by VSV-ZEBOV vaccination, with specific emphasis on trancriptomics and metabolomics signatures. To this aim, we have constructed a consortium including representatives from the vaccine manufacturer, scientists of the 3 main clinical sites (Switzerland, Gabon, Kenya) and world-leaders in immunology and partners of ADITEC, a large FP7- supported collaborative research programme aiming to accelerate the development of novel, powerful immunisation technologies for next-generation vaccines. We propose an ambitious program using cutting-edge technologies to perform an in depth characterization of the clinical samples harvested before/after VSV-ZEBOV immunization of 200 volunteers in Switzerland, G
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Professions in International Political Economies' (PIPES).

assistant: **Concept**

Who writes the rules for the governance of the world economy? The Professions in International Political Economies (PIPES) project is concerned with how professional actors compete in public and private arenas to provide solutions to policy problems. This project provides an original framework to understand how actors in professions shape global economic governance in a manner that commonly ignores public-private distinctions. Rather than conforming to public-private or national-international distinctions, actors create networks through their professional skills. From this context, networks of actors form strategies that link their profession to others to dominate how particular policy problems should be understood.Actors in professions form coalitions and alliances to protect their power and prestige, as well as to create consensus on how to treat policy problems and what represents world’s best practice. Since actors never really have control over how ideas are interpreted they must strategize in an ongoing fight for control over how certain problems should be understood. PIPES is concerned with mapping how professions fight over how to solve policy problems across a range of issue-areas in the world economy where there is a change in economic practices and markets. These are divided into four areas of governance: finance; health; capacity building; and the environment. Among others, topics to be studied include risk management technologies in finance, low fertility problems in the OECD, and the development of carbon ratings markets. The PIPES research team employs a mixed methods approach that combines qualitative structured and focused comparisons from primary evidence (interviews and primary documents) and participant observation, as well as quantitative analysis t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Image-guided pancreatic cancer therapy' under Seventh Framework.

assistant: **Concept**

The aim of the iPaCT project is to address the unmet clinical need for an improved therapy of pancreatic cancer by developing a new integrated technology platform for image-guided thermal therapy. Yearly, 280000 new cases of pancreatic cancer are diagnosed worldwide. Being usually diagnosed late stage and without any efficient therapy available, basically all patients die with an average life expectancy of only a few months after diagnosis, leading to an overall low prevalence in society. Therefore, pancreatic cancer is a rare disease with an urgent clinical need for a new and improved therapeutic option.A potential breakthrough solution for the treatment of pancreatic cancer can be found in thermal therapies using high intensity focused ultrasound (HIFU) combined with local, temperature-triggered drug delivery. We propose a novel US-MR-HIFU system that integrates HIFU with two imaging modalities, i.e. Magnetic Resonance Imaging (MRI) and diagnostic Ultrasound (US) for image guidance of thermal ablation (T=60⁰C) and/or hyperthermia (T=42-43⁰C) of pancreatic tumours. For image-guided drug delivery, new temperature-sensitive nanocarriers will be developed that provide a high local dose of chemotherapeutic drug. Multimodal (molecular) imaging information, simultaneously acquired using the US-MR-HIFU platform, provides motion compensated temperature feedback as well as visualization of perfusion and drug uptake in the target tissue allowing personalized therapy.The consortium, including two innovative SMEs (Imasonic, Neagen), two hospitals (Klinikum der Universität München and University Medical Center Utrecht), Eindhoven University of Technology and Philips (a medical device company), represents the total chain from technology development, preclinical testing to clinical t