RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Harnessing ICT-enabled collective social behaviour' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The last decades have seen a tremendous change of society as a whole, driven by Information and Communication Technologies (ICT). The dynamics of building and strengthening social relationships have evolved through the use of ICT, and new ICT-mediated groups and communities have emerged. Individuals, communities, society, and ICT have become deeply intertwined in a dynamic feedback process. The fundamental challenge for future social ICT is overcoming the acute lack of understanding of the driving forces and mechanisms of this complex system of interactions. The project aims to develop systematic exploration, understanding, and modelling of systems where ICT is entangled with social structures. Currently, there is no general understanding, either at the individual or collective level, of how ICT-mediated social interactions and patterns of influence work. In particular, there is a critical gap in our understanding of how different levels of social behaviour are related to each other. Moreover, the existing knowledge in this area is highly fragmented between different scientific disciplines such as social psychology, computer science, and complexity science. A major goal of ICTeCollective is to bridge this gap, by using multi-level and multi-scale approaches to understand ICT mediated social dynamics at a societal level in relation to micro- and meso-scale processes. This goal will be achieved by carrying out original experiments on the impact of ICT on human behaviour, analysing ICT-generated large, unique, and time-stamped datasets, constructing and investigating models and building up a more general theoretical framework. This interdisciplinary approach of ICTeCollective will produce new insight and integrate the fragmented knowledge of different scientific discipline
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Iron uptake in Chromera velia and other marine microalgae' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Recently discovered marine alga Chromera velia represents the closest known free living photosynthetic relative to obligate parasites Apicomplexa. C. velia is easy to cultivate, thus representing a powerful model for studying organisms living in nutritionally poor ocean environment as well as a model to study the evolution of parasitism. For most marine microorganisms the mechanisms of adaptation to extremely low iron levels in surface seawater are unknown. We have recently described in C. velia a novel non-reductive two-step model of iron uptake. In this project we will further study the mechanism of iron uptake system in C. velia and characterize it at the molecular level. Furthermore, we will compare iron requirement, uptake mechanism and storage in various microalgae belonging to different phyla. Our preliminary experiments suggest great diversity in the requirement for iron among different marine microalgae. We will try to elucidate if these differences are related to the diversity of the mechanisms of iron acquisition and storage.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'DIVERSITY OF LOCAL PIG BREEDS AND PRODUCTION SYSTEMS FOR HIGH QUALITY TRADITIONAL PRODUCTS AND SUSTAINABLE PORK CHAINS'.

assistant: **Objectives**

Research and development activities are proposed for the benefit of sustainable pork chains based on European local pig breeds and their production systems. Workprogramme is planned to respond to consumer demands for quality and healthiness of pork products with regional identity and societal demands for environment preservation and development of local agro-economy. Description and evaluation of local pig breeds, with an emphasis on untapped ones will be performed using novel genomic tools. Performance of local pig breeds will be evaluated in contrasted agro-geo-climatic conditions and production systems (indoor, outdoor, organic). Focus will be on pig feeding and management strategies and on the use of locally available feeding resources. Intrinsic quality of traditional and new regional high quality pork products and attitudes of consumers from various market areas will be assessed; in particular the motives for the choice and willingness to pay such products. Marketing strategies will be adressed in particular short chain distribution channels. All activities will be driven from the perspective of sustainability (environmental impact, animal welfare, product quality, consumer acceptability and market potential). The activities will engage innovative approaches to answer socio-economic demands of regional pork chains involving partners from different sectors. The ambition is to enhance existing and create new networks between academia and non-academia partners, within and between regions and to tackle the value chain for regional high quality pork products, focusing on diverse and so far untapped pig breeds, their production systems and pork products. Cross-fertilising interactions between research, local agriculture, businesses and end-users will be achieved with pa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Activation and Regulation of the NLRP3 Inflammasome', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The innate immune system protects the host from infections, detects and repairs tissue damage and functions to maintain tissue homeostasis. Several families of signaling receptors can recognize microbial substances or altered host molecules and orchestrate a coordinated inflammatory response. Inflammasomes are signaling platforms that control proteolytic activation of highly proinflammatory cytokines of the IL-1β family and thus, are relevant for infection control and numerous inflammatory conditions. In addition to recognizing foreign signals, the NLRP3 inflammasome can sense sterile tissue damage and various endogenous danger signals that appear in many common chronic inflammatory conditions. NLRP3 can be triggered by material released from dying cells and aggregated or crystalline substances, and its activation has been implicated in the pathogenesis of prevalent diseases in Western societies, such as type 2 diabetes, COPD, atherosclerosis and Alzheimer’s disease. The NLRP3 inflammasome can be activated by diverse signals however, the molecular mechanisms leading to its activation remain poorly understood. Using chemical biology screens and proteomics analysis, we identified that NLRP3 activity is regulated by phosphorylation and ubiquitination. This project aims to identify the enzymes and signaling mechanisms leading to NLRP3 activation. In an integrated, multidisciplinary approach, we will employ chemical biology screening to identify novel targets that act to regulate NLRP3, and will describe the NLRP3 interactome in response to various triggers. Data obtained by these approaches will be analyzed by bioinformatics, and signaling mechanisms identified will be confirmed by RNA interference and gain-of-function studies. Utilizing a range of biochemical, biophysical
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'The rhythms of our mind. A mechanistic model of how oscillating body-brain states structure human cognition'.

assistant: **Concept**

We live in a rhythmic world. Take a deep breath, listen to your heartbeat, to the trees swinging with the wind, music playing, people chatting. Every perception and cognition, every heartbeat happens in time following its own rhythmic frequency. Our brain also generates rhythmic brain waves and there is wide consensus that these neural oscillations are a fundamental building block of how our brain works. Interestingly, the brain is not the only organ generating such intrinsic rhythmic signals. Bodily rhythms such as heartbeats, breathing or gastrointestinal activity can also be described as endogenous oscillators. But are these brain and bodily rhythms functionally relevant for how we perceive the world? Could it be that these rhythms determine what we attend to, what we remember and how much information we can store in our mind? This ERC proposes a new perspective on how oscillating body-brain states structure our cognition. We hypothesize that brain rhythms enable us to adapt to changing cognitive demands by flexibly switching between two fundamental operating modes: (i) to support communication between brain regions (WP1), and (ii) to code for the mental representation of specific content in our mind (WP2). We further propose that bodily rhythms can also dynamically tune their coupling strength with the brain in a state-dependent manner (WP3), supporting the operating mode of neural oscillations when being in “flow” (WP4). We formalize these hypotheses in a proposed FLexible Oscillatory Workspace (FLOW) model and empirically test our predictions using a noninvasive “brain pinging” approach for causally probing state-dependent rhythmic body-brain coupling mechanisms. In a final proof-of-principle project, we will then use rhythmic non-invasive neuromodulation for entr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Designing all-CArbon-based colour tunable Random Lasers for speckle free Imaging applicaTiOns (CARLITO)'.

assistant: **Concept**

The practical application of conventional lasers is often hampered by inherent difficulties related to their bulky, expensive and highly coherent nature. Some of these issues can be overcome by so-called Random Lasers (RL), devices in which laser emission stems from the random walk of photons in a disordered medium. However, achieving efficient, tunable, and stable RL remains difficult to date. A large variety of nanostructured metals and semiconductors, organic dyes and quantum dots (QDs) were proposed as passive or active scatterers to fabricate RLs. However, organic dyes usually suffer from rapid photo-bleaching, while semiconductor QDs are affected by fluorescence blinking and their toxicity can be a serious pitfall in biomedical RL applications. CARLITO proposes the use of carbon nanostructured materials (CNMs) to design an entirely new class of RLs for a wide range of photonic applications, where a stable and low-threshold RL is obtained by the combined use of different CNMs as active and passive light scatterers. The ambitious goal of CARLITO is designing the first all-carbon-based RL (ACRL), capable to yield high-quality RL from hybrid CNMs, by taking advantage of the peculiar electronic properties of different zero-, one- and two-dimensional nanocarbons. ACRLs will be a new family of low-cost, non-toxic and fully biocompatible RL devices, which can be easily tuned to emit photons within the entire visible spectral region. Achieving these targets will advance RLs well beyond the current state-of-the-art, favouring their transition into real-world technology, such as in live cell microscopy, speckle free imaging and sensing. In particular, the application of ACRLs in speckle free imaging will be directly tested within the scope of CARLITO.


**Keywords:** Carbon
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Novel enzyme-aided extraction technologies for maximized yield and functionality of bioactive components in consumer products and ingredients from by-products' under Fifth Framework.

assistant: **Concept**

MAXFUN will develop novel enzyme-aided processing technologies for grape and berry applications with special emphasis on increasing the yield and enhancing the quality of the final consumer products, i.e. juice or wine. Enzymatic treatments will be combined to selected novel physical/physicochemical and mechanical treatments . The same technologies will also be applied for extraction of valuable food ingredients from the current process by-products . Bioactivity assays and in vitro models will elucidate the potential health-promoting value of consumer products or novel ingredients. The sensory quality of the improved products will also be studied. Finally, the consumer attitudes and acceptance of products manufactured with the new technologies will be assessed together with an economical and process technical feasibility analysis.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Spatial and Orbital Light for Advanced Systems' (SOLAS) targeting Seventh Framework.

assistant: **Abstract**

SOLAS project targets the development of disruptive spatial division multiplexing technology merged with the radical new technology of orbital angular momentum fibres to deliver low cost, high capacity communication networks of the future. The proposed concepts will be implemented using spatial division multiplexing as the base technology platform along with orbital angular momentum fibres that provide greater total capacity than current single mode fibres. SOLAS aims to develop new and simplify existing subsystem technologies to allow for a smooth and efficient transition to communication technologies of the future while maintaining compatibility with existing technologies. Furthermore, it offers a continued European leadership in RTD photonics from components to systems, securing the necessary human resources and knowledge to design and produce a new generation of photonic components that support EU’s vision for ubiquitous broadband connectivity to promote European social and economic cohesion and prosperity.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Comparative epidemiology of genetic lineages of Trypanosoma cruzi' to be submitted under Seventh Framework.

assistant: **Abstract**

The focus of this multidisciplinary proposal is to elucidate the epidemiology of the genetic lineages of T. cruzi, for improved understanding and prevention of Chagas disease.  The project will unite skills in genotyping, genomics, genetics and pathogenesis in Europe with considerable compatible skills in South America, and with key research in endemic areas that have distinct characteristics. The proposal is intended to be high impact in terms of both research progress and fostering of collaborative networks. Aim: Elucidate the epidemiology of the genetic lineages of T. cruzi, for improved understanding and prevention of Chagas disease.  Technology development: 1. Develop further and apply MLST; PCR-RFLP and MLMT to the analysis of genetic populations of T. cruzi, 2. Sequence the unresolved genome of T. cruzi I, 3. Develop lineage specific diagnosis, 4. Develop an oligochromatography PCR-dipstick procedure for detection of T. cruzi. Molecular epidemiology: 5. Pilot studies of association between genetic lineage, clinical outcome, and prevalence of congenital infection, 6. Map the silvatic vector, silvatic mammal, human and ecological associations of the T. cruzi genotypes IId,e,b,a. 7. Compare lineage specific pathogenesis and transmissibility of congenital infection in a mouse model, and compare lineage susceptibility to drugs in vitro. Population genetics and phylogenetics: 8. Re-evaluate the population genetics and evolution of T. cruzi lineages.  International cryobank and database: 9. Establish in South America an accessible, expanded, international cryobank for T. cruzi, 10. Establish a website and database for outputs of the project.        The project encompasses the desirable characteristics prescribed by the call, in that they include: genomics/proteomics; ef
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Development of novel system for continuous remote monitoring of weight, growth, and size distribution of fish in aquaculture enclosures' (FISHSCAN).

assistant: **Innovation**

Today there is ±5% error in estimation of biomass in fish farming. This represents € 91M in loss for the European fish farming industry. Around 80 % of all sales of farmed fish are arranged pre-harvest.  To make profit on the sale, farmers and processors are dependent on correct estimations of weight, size distribution and total biomass.  Furthermore, fish feed constitutes 50% of the production costs in fish farming. Cost of excess feeding is therefore high.  It is a fact that European fish farmers have been facing serious competition from low cost countries during over the recent years, especially the sea bass & bream sector in southern Europe. The FishScan project will develop a novel system for continuous remote monitoring of weight, growth and size distribution of fish for use within aquaculture enclosures.  The aim is to achieve an accuracy of 99% in size measurements for fish > 1kg, and 97 % for fish at 100g. The FishScan system has a potential in aid a reduction from the current ±5% to ±3% error in biomass estimates. This represents increased profit of € 40,445 p.a. per farm license and corresponds to economical benefits of €41M p.a. in increased profits for the European aquaculture industry. To achive this, the FishScan project will: Increase knowledge of fish behaviour in net cages to enable representative sampling; Transferring Time-of-Flight (ToF) technology and software to an aquaculture setting;  Design robust camera module & optimise LED power & positioning; Design translation system for movement of camera module in fish cage; Develope software for use underwater on fish; Develop LED driver to increase frequency from 20MHZ up to 40MHz to increase depth resolution of ToF data; Design control system for  camera module movement, light settings and camera and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Gravitational Physics from the Universe Large Scales Evolution' (GraviPULSE).

assistant: **Concept**

How does gravity work on cosmological scales? Starting from July 2023, for the very first time in the history of space science, the geometry of the Universe Large Scales will be mapped by the Euclid mission, providing the scientific community with a wealth of cosmological data of unprecedented quantity and quality. It will be a transformational moment that will open a new ground for testing gravity; yet, unless combined with a theoretical framework able to translate wonderful numbers into concepts, this is bounded to be a missed opportunity. This research program - whose proponent is currently serving in the role of co-Lead of Euclid Theory Working Group - aims at constructing such a framework.Euclid will compare the action of gravity on light with that on non-relativistic particles, in a regime vastly different from where General Relativity has been confirmed. Any significant detection of a deviation, will have profound consequences. But how to confidently dissect and decipher these potential signals? In the past years I have laid the ground work for cosmological tests of gravity, culminating recently in a first reconstruction of gravity from available data. These results are at their infancy and a leap beyond the current state of the art is urgently required to breach into the smaller, nonlinear scales where statistical errors will be at their lowest. The timing could not be better, with data releases of Euclid expected during the tenure of this proposal.From an exhaustive exploration of the gravitational landscape under criteria of theoretical viability, we will create predictions of the Large Scales phenomenology by broad classes of theories, with an accuracy that meets Euclid requirements. These will be used to construct a comprehensive phenomenological framework e