RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Genes, Mediterranean dietary pattern and metabolic syndrome risk' (METSGENES), addressing dissemination and exploitation.

assistant: **Impact**

The MetS, a cluster of metabolic abnormalities, is of interest from a public health perspective because early intervention amongst these individuals may prevent the development of serious health complications such as diabetes (DM). The prevalence of MetS is 20–30% among adult populations in most countries, and individuals with the MetS have a 6-fold increased risk of DM. Atherogenic dyslipidemia is also involved in the pathogenesis of DM because insulin regulates several of the steps of lipid metabolism. To understand the progression of the disease, it is necessary to consider both candidate genes for involvement, as well as factors related to the advancing age or the environment, diet and lifestyle.Genomics and epigenomics are revolutionizing biomedical research areas that can hopefully decipher some of the gaps in our current knowledge of cardiovascular risk factors. This proposal aims at studying the possible interactions among several candidate genes for MetS-related traits or DM using a genetic predisposition score (GPS), the adherence to the Mediterranean dietary pattern and the risk to develop MetS as well as the influence of classical and new biomarkers related to MetS-traits, in order to prevent/delay the onset of MetS in a European population. It also aims at studying the replication of these gene-diet interactions in different American populations. Furthermore, this proposal aims to examine the expression of microRNAs related to cholesterol and lipoprotein metabolism in the enterocyte cell line; and to dissect the influence of dietary polyphenols (important components of a Mediterranean dietary pattern) and other bioactive food components on the expression of microRNAs related to cholesterol and lipoprotein metabolism as strategy to manage dyslipidemia.This p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Evaluating the variability of ecosystem water vapour fluxes and spatiotemporal effects of extreme events' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Water vapour fluxes are a key variable in the biosphere-atmosphere exchange of water in terrestrial ecosystems and have strong interactions with the climate system. However, research on the effects of climate change has been largely focused on carbon cycling and therefore, many open questions remain, in particular with respect to the long-term variability of water vapour fluxes and to spatiotemporal patterns in ecosystem responses to extreme events. The project ECOWAX intends to close this knowledge gap and contribute to a better understanding of ecosystem water cycling, thus assisting in the development of mitigation options to secure water supply for human society in a changing climate.The overarching goals of ECOWAX are (1) to assess the intra- and interannual variability of ecosystem water vapour fluxes across biomes and climate, and (2) to evaluate spatiotemporal effects of extreme events on these fluxes. To achieve these goals, ECOWAX will combine water vapour fluxes measured in situ from a new synthesis dataset of the global measurement network FLUXNET with a novel biophysical process model (BESS – Breathing Earth System Simulator) to upscale ecosystem fluxes globally for spatiotemporal analysis.The research objectives of ECOWAX are (1) to investigate the range and magnitude of intra- and interannual variability of water vapour fluxes across biomes and climates using the FLUXNET synthesis dataset, (2) to improve the novel biophysical model BESS to overcome current limitations, (3) to upscale water vapour fluxes globally with the improved version of BESS and validate the model results with site data from FLUXNET, and (4) to assess the spatiotemporal variability of water vapour fluxes and the effects of extreme events on these fluxes in Europe during the last decad
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'How citizens try to influence politics and why. International comparisons of movement and party politics' (POLPART), addressing dissemination and exploitation.

assistant: **Impact**

Protests in ‘new’ democracies about ‘stolen elections’, demonstrations in ‘old’ democracies against austerity measures, occupied squares all over the world against inequality and for better governance. Some argue that contentious politics gains importance and party politics declines. Is that so and why would that be? Why is it that some individuals engage in politics while others remain apathetic? Why is it that some citizens take the electoral route, while others engage in contentious politics? The truth is that we do not really know. Should we bother? I think we should. Citizens who are actively involved in politics are an asset to democracy. Understanding how and why people take part in politics would help to build more democratic societies.The proposed project compares participation in contentious and non-contentious politics in various countries within a single theoretical and methodological framework. A central tenet of this research proposal is that sooner or later every citizen might get involved in politics. I seek the reason why in the interplay of dynamics at the individual, the organizational, and the societal level. What are the motives people have? What are the appeals parties and movement organizations disseminate; and what are the opportunities and constraints regimes impose?Comparison is the core of the project. It encompasses four subproject: (1) a meta-analysis of publications on movement and party politics; (2) comparisons of political participation over time and countries in global survey data; (3) focus group discussions to understand the formation of political engagement and disengagement in four ‘old’ democracies (the Netherlands, Germany, Switzerland, U.S.A.), two post-communist ‘new’ democracies (Hungary, Romania) and two post-authoritarian ‘ne
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Rethinking Disability: the Global Impact of the International Year of Disabled Persons (1981) in Historical Perspective' in the context of a Horizon 2020 call.

assistant: **Objectives**

Approximately 10% of the world’s population is estimated to be disabled and this number is expected to rise in the next few decades. People in different cultural settings ascribe different meanings to disability; consequently, its repercussions are both culturally contingent and universal. This project brings together the local and global dimensions of disability and examines the interaction, tension and conflict between these two aspects by undertaking the first comprehensive study of the far-reaching political, societal and cultural implications of the International Year of Disabled Persons (IYDP) which was organized under the auspices of the United Nations in 1981. A landmark event which appears to have gone virtually unrecognized in scholarship; the IYDP was the first occasion to place disability into a global context by endorsing it authoritatively as a human rights issue and thereby raising the question as to how the concept may be understood in a multicultural world. There will be four closely-related objectives: 1. to examine the IYDP’s impact on human rights discourses and to scrutinize their applicability within global settings; 2. to document the IYDP’s contribution to emancipation and social change and to consider the different trajectories of emancipation in various parts of the world; 3. to assess the ways in which the IYDP influenced everyday life experiences, galvanized identity formation and inspired the emergence of a distinct subculture; 4. to analyze the transnational exchanges and knowledge transfer in conjunction with the IYDP and to examine how the Western oriented discourses penetrating the developing world interacted with the local environment. The project’s innovative contribution and academic impact lies in connecting the IYDP to broader polit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'SUPPRESSION OF RNA SILENCING BY PLANT PARARETROVIRUSES: PROTEIN VERSUS RNA-BASED?' (SUPRA).

assistant: **Concept**

Plants defend themselves against viruses by generating virus-derived small interfering (si)RNAs and thereby silencing the viral genome. Viruses counteract this defense by producing suppressor proteins. We have evidence that not only proteins but also viral RNAs could be used as suppressors: the extreme accumulation of siRNAs from a 600 bp leader region of Cauliflower mosaic pareretrovirus (CaMV) suggests that this region acts as a decoy to divert the silencing machinery from the viral coding regions. This highly-structured leader of the pregenomic 35S RNA is a hindrance for scanning ribosomes, which have to bypass it by a shunt mechanism to initiate polycistronic translation. Early literature described a CaMV “8S RNA”, which covers just the leader region. We shall investigate whether 8S RNA of CaMV and related pararetroviruses such as Rice tungro bacilliform virus (RTBV) serves as a precursor of virus-derived siRNAs, whether it is produced by run-off transcription from the gapped viral DNA as a short-stop RNA and/or whether Met-tRNA, which primes viral reverse transcription, is also involved in creating the siRNA precursor. We shall test whether transient or stable over-expression of the CaMV and the RTBV leader region in a single-stranded or a double-stranded RNA form is able to suppress silencing. These studies should reveal whether a short-stop RNA-based suppression is a universal mechanism employed by plant pararetroviruses and, perhaps, also animal retroviruses. Additionally we shall identify protein-based suppressor(s) in RTBV and associated Rice tungro spherical virus, an RNA picorna-like virus, and study whether synergistic suppression of silencing by two or more viral suppressors, whether RNA- or protein-based, might contribute to severity of the rice tungro di
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Human stem cell applications for the treatment of hearing loss' under Seventh Framework.

assistant: **Concept**

Hearing impairment is the most frequent human sensory deficit and is mainly caused by the irreversible loss of neurosensory cells in the cochlea. The lack of human otic cell models represents a significant roadblock that has hampered the development of drug-based or cell-based therapies for the treatment of hearing loss. In a collaborative effort under this proposal we wish to devise approaches to generate human otic progenitors and differentiated otic cells from different human stem cell sources. We have devised guidance protocols for mouse and human embryonic and reprogrammed stem cells toward inner ear cell types that make use of principles of early germ layer formation and otic induction. A limitation is the efficacy of otic progenitor cell generation. Purification techniques for human otic progenitors from ES/iPS cell sources and in addition from native human otic tissues from fetal and adult stages will will serve the dual purpose for one to enable the development of novel bioassays for drug screens, as well as generating cells with decreased tumorigenicity for cell transplantation studies in in vivo animal models. New hit compounds identified from screening efforts will be tested and validated further in established organ culture models. The identification of relevant candidate compounds will be further developed as lead drug candidates in noise and ototoxic drug induced in vivo models. The scope of this stem cell technology development requires a collaborative team effort, with groups that have substantial combined experience in human ES/iPS cell work, inner ear stem cell biology, high-throughput assay development, and in translating research findings into the clinic as well as into the biotechnology realm. Within the consortium there exists an established trans
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Software tools for fast, reliable analysis of magnetic materials in the electron microscope' (MAGTOOLS).

assistant: **Innovation**

This proof-of-concept project aims at developing a software tool to be integrated in commercial electron microscope control platforms dedicated to the development of novel magnetic materials. Magnetic materials have applications in different areas such as data storage, sensors, biomedical applications or spintronic devices. Future technological developments will come hand-in-hand with new materials based on novel atomic arrangements, and electron microscopy is a unique technique to analyze nature in an atom-by-atom fashion. Recent improvements in microscope performance ensuing from the correction of optical aberrations are already commercially available. However, a successful transfer of specific, advanced tools into a wider technology development context needs of user-friendly interfaces that can help non-specialist researchers and engineers fully exploit these techniques. This is a particularly pressing need for the magnetic material industry, since a number of techniques sensitive to magnetic quantities have been demonstrated in the electron microscope in the last few years. But the field development is incomplete because they are hampered by time-consuming data acquisition and analysis procedures. No tools exist that are capable of fast optimization, acquisition and analysis of data at the flick of a switch. Here, we propose to fill this gap and develop an optimal software tool ready to be marketed by specialized technical companies. It will consist of an interface that will control and modify the excitations of magnetic lenses, the detectors in charge of data acquisition and, also analyze datasets and calculate parameters relevant to the magnetic behavior of samples of interest. These tools will provide the means to give a new spin to research into the magnetic mat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Peer to Peer Property' (P2Property) targeting Horizon 2020.

assistant: **Abstract**

We will do to estate agents what Opodo did to travel agents, eBay did to secondhand shops, and Airbnb is doing to hotels. By getting rid of the middleman in favour of a peer-to-peer participatory model, we will bring the property market in line with the changing needs of society and the rapid pace of technology. Our solution is a technology platform called Qoob that lets you rent property directly from your phone, making estate agents a thing of the past. Described by the Daily Mail as ‘the Tinder of property’, our platform makes property transactions cheaper, faster and globally consistent. It lets owners list their properties and tenants list their needs. Both can browse, make a match and exchange rent, even at short notice or for an undermined length of time. Our technology will reduce cost, increase flexibility and bring Europe-wide consistency to finding accommodation. By letting owners set their own terms, we will catalyse a market correction in which shorter and flexible tenancies are found in proportion to demand. Qoob is part of a paradigm shift from ownership to access, offering citizens a means of agile moving and renting.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Integrating social science research into cotton reform implementation lined with the international outlook' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

The New cotton CAP Reform signed in 2004 entered into effect in January 2006. This reform represents a radical change as support is disconnected from production and decoupled payments are introduced. In spite of the thoroughness in formatting the new CAP Reform, it is hard to argue that it is perfect and will not require future amendments. Thus, a thorough contemplation of the consequences of CAP reform is required, notably in the cotton case, as new changes seem eminent both for internal and external reasons. _The implementation of the New CAP reform will have great implications for producers and processors of cotton products in certain EU regions whose economies are deeply depending upon cotton production. To ease implications, a careful monitoring, evaluation and adjustment is required. _The EU Cotton Policy is under critique by African cotton producing countries since the WTO Ministerial Meeting in Canc?n in September 2003. The EU international commitments within WTO clearly call upon new criteria to be taken into account in CAP's implementation and evolution. Apart from the change in allocating income support to its farmers, EU retains also governance principles based upon the participative approach by further involving sector stakeholders and on the other hand, EU retains the contribution from researchers to provide scientifically-based policy orientation. The global objective of the proposed project is to assess the impacts of cotton CAP reform and the future of the sector through promoting a participatory and scientific approach. This global objective depends on the completion of three interconnected specific objectives: 1.Launching a self-sustained national process of interaction among producers, consumers and stakeholders on EU Cotton Policy. 2.Contributing to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'A thermal imaging based part inspection tool to enhance the competitiveness of the large group of SMEs within the EU injection moulding Industry' to be submitted under Sixth Framework.

assistant: **Abstract**

Industrial ObjectivesThe principle objective of this project is to develop a new low cost Thermal Imaging based Part Inspection System that allows injection-moulders to rapidly identify parts that are likely to develop failures, as a consequence of cooling or future expensive reprocessing such as painting and chroming, before the parts are cooled down, thereby saving hours of wasted production. The proposal will address the 7,50bn EU problem of process failure and waste in the injection moulding sector.The prototype development of the thermal imaging based part inspection system will improve the competitiveness of the large community of 25,000 SMEs in the EU injection moulding sector by facilitating a productivity improvement of 2%and decreasing waste with 10%. This will provide the plastic processing sector with the necessary momentum to increase our competitiveness against non-EU competition by contributing towards our efforts to off-set the labour cost advantages of our Asian competitors.