RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Identification of Defence responses instigated by Extra-cellular Ascorbate in plants' (IDEA) under Sixth Framework.

assistant: **Objectives**

Plants must survive the vagaries of the natural environment and have developed an intricate web of defences to combat stresses to which they are exposed. Unravelling the mechanisms by which plants sense and respond would be a major breakthrough in fundamental scientific understanding and highlight key pathways for targeted manipulation to improve crop yields. A common denominator in the reaction of plants to stress is the production of a suite of hazardous reactive oxygen species (ROS). This causes shifts i n the amount and redox status of key antioxidants, in particular ascorbate (ASC) and glutathione (GSH), a signal which can be sensed and transduced by the plant. To date, attention was focused on defence-related gene expression caused by cellular ASC and G SSH, yet the primary source of ROS is the cell wall. It would thus make sense for key redox sensors and transduction elements to be situated in this poorly understood sub-cellular compartment. Recent work published by the host laboratory has employed novel transgenic plants to illustrate the importance of extracellular redox status of ASC in modulating defence-related gene expression.The proposed project will draw upon the accumulated knowledge and provide access to characterized transgenic plants plus a u nique mix of state-of-the-art facilities (cat2 O3-fumigation suite co-located with MALDI TOF-TOF MS, SELDI-TOF MS and MUDPIT technology) in a bid to identify changes in the leaf proteome instigated by shifts in the redox status of extra-cellular ASC. Leaf and cell wall fluid will be sampled at regular intervals from plants exposed to O3. Differentially expressed proteins will be sequenced and identified with support from the hosts Bioinformatics Support Unit. The work proposed will clarify the role played by extr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Juxtapositioned reflective performance enabling science and technology learning' under Seventh Framework.

assistant: **Concept**

School and University students studying science and technology often encounter barriers to their understanding of complex concepts.  However, unlike in the arts, students are frequently poorly motivated to overcome these barriers.  Focusing on 'performance' JuxtaLearn will provoke student curiosity in science and technology through creative film making and editing activities. Computational identification of students' barriers to conceptual understanding will be overcome by  scaffolded creative application of concepts in activities juxtaposed to traditional understanding.  State of the art technologies will support students transferable reflections focusing on two pedagogical approaches:  juxtaposition performance and reflective performance.<br/>Juxtaposition performance: JuxtaLearn ICMAs (Interactive Computer Marked Assessments) will support students' identification of threshold concepts that are their own personal barriers to understanding.  Students' understanding will be enhanced by them creating personal performances through application of a theory in a formal activity and then again in a creative juxtaposed activity (e.g. physics used in music DJ-ing, chemistry occurring in kitchens, possible evolution of an alien race).  New media and learning analytics of public video resources will facilitate student creative inspiration and further conceptual insight and understanding.<br/>Reflective performance:  State of the art systems for automated and personalised film making and editing will support curiosity and creative expression.  A deeper understanding will be reinforced through scaffolding reflections on essential elements in applying the theory.  Students will, for example, be supported in instigating reflective decisions on what to film, how to film it and what an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'EGO Portable: A Portable, small size, modular solar water heater suitable for different applications with do-it yourself installation' to be submitted under Horizon 2020.

assistant: **Abstract**

Non-renewable energy sources are the cause for GHG emissions and of expensive energy bills for EU citizens (electricity &gas bill counts up to 145€/month/household). The biggest impact on GHG emissions is given by energy used for heating (space and water heating). The water heating demand represents 10% of the overall heating energy demand in Europe (forecast of 21% by 2050). The Renewable Energy Directive (2009/28/EC) and the Energy Performance of Buildings Directive (EU) 2018/844, which is part of the Clean Energy Package, set binding targets for 2030 regarding renewable energy sources, energy efficiency and reduction of GHG emissions. Solar thermal energy can contribute achieving these goals with a potential to cover up to 47% of heat demand by 2050. State of the art solar water heaters (SWH) are big (up to 2m length) and heavy (40-100kg) and can only be installed on rooftops. Thus, by now, the use of SWH depends on the customers access to a rooftop. Moreover, traditional SWH have high installation costs (up to 800€).Pleion is an Italian company leading the Solar Thermal Market since 2008, wants to introduce to the market a light and small Solar Water Heater, suitable for unlimited application fields. Its compact, portable and modular nature allows EGO Portable to be installed wherever the customer needs hot water (balconies, campers, yachts, boats etc.). A reliable and simple design with an intuitive connection system and a kit with safety component will allow the customers to self-install EGO Portable saving installation costs and efforts. Pleion Srl targets a decrease of up to 209 kg CO2 annually per sold unit of EGO Portable and from a social point of view, the company will support humanitarian causes by creating the possibility the access to hot water in emergen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Measuring the inverse local Compressibility in suspended Graphene devices' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The discovery of graphene by Novoselov and Geim (Nobel prize 2010), has opened up a new era in the study of quantum physics. Graphene, a monolayer of carbon atoms arranged in a honeycomb structure, is the only one-atom-thick conducting membrane and its novel properties provide the opportunity for unprecedented device functionality such as ultrafast, flexible and transparent electronics. A field of particular interest within graphene research are the effects of electronic interactions and elastic deformations. The consequences of electronic interactions in graphene devices are currently under intense investigation, both theoretically and experimentally. On the other hand, elastic lattice deformations due to external strain modify the single particle electronic density of states (DOS). Specific strain patterns result in pseudo-magnetic fields and the appearance of Landau levels. Many open questions arise from the interplay between pseudo- and real magnetic fields and the role of electronic interactions in strained graphene membranes.In this project we will address the role of interactions and lattice deformations in graphene membranes experimentally. Suspended graphene membranes are the ideal devices to investigate these effects due to their high electron mobility and possibility to engineer strain. Here, we propose to develop on-chip suspended single electron transistors to measure the local electronic compressibility of suspended graphene membranes. The electronic compressibility is a thermodynamic quantity and a direct measure of the many-body DOS. To investigate interactions on a microscopic scale it is essential to gather information locally. A macroscopic measurement averages over sample inhomogeneities and smears out microscopic features. Measuring the many-body DO
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Enantioselective Synthesis of Madangamine Alkaloids via Organocatalytic Desymmetrization' (ESOMAVOD).

assistant: **Concept**

This project will develop a new, highly enantioselective, state-of-the-art synthetic route to madangamine alkaloids B, C and E based on a novel organocatalytic desymmetrization reaction as a key step, which will allow the rapid and efficient construction of the AC rings ready for subsequent advancement to the majority of the family members. Evaluation of the anti-cancer biological activity of the different madangamines and late stage intermediates will be carried out. This Fellowship project combines total synthesis, new asymmetric methodology development via organocatalysis and biological evaluation. This multidisciplinary Fellowship, based on high-quality and novel research at the University of Oxford, one of the top-research centres worldwide, has been designed to augment and complement Dr Vasu’s skills and knowledge to improve his career possibilities and, at the same time, Dr Vasu’s experience in new methodology development and catalysed transformations will be advantageous to the design of the organocatalyst in the key step of the synthesis. The Fellowship will also be useful to establish new collaboration opportunities for the Dixon group. Through the training and the research results arising, the Fellowship will be beneficial to the fellow, the host institution and European science.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Development of screening guidelines and diagnostic criteria for predementia alzheimer's disease (DESCRIPA)' in the context of a Fifth Framework call.

assistant: **Objectives**

The primary goal of the study is to reach an evidence-based European consensus on the identification of subjects with Alzheimer's disease (AD) in the preferential stage. The secondary goals of the project will be to develop diagnostic criteria for preferential AD in a clinical setting and screening guidelines for preferential AD in the general population. The clinical criteria will be based on pooled data from six prospective studies of subjects with mild cognitive complaints that have investigated markers of preferential AD. The screening guidelines will be based five population-based studies that have investigated markers of preferential AD.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Neuromorphic computing Enabled by Heavily doped semiconductor Optics' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

NEHO will develop a novel photonic integrated circuit platform that enables ultrafast and low-energy consumption neuromorphic information processes by means of a newly developed nonlinear photon-plasmon semiconductor technology at mid-infrared wavelengths (8-12 μm). NEHO vision will be achieved by unconventional use of semiconductors to optimize and control plasmonic effects that will provide the optical nonlinearity required to implement the functionalities of an artificial neuron. NEHO's optical neuron will be the building block for the realization of ultrafast optical neural networks.  We will combine the flexibility of field-effect devices realized on semiconductors with the nanoscale nature of plasmonic processes so to enable the reconfigurability of the nonlinear optical coefficient at each node of the network, simply obtained by controlling DC electric potential levels. At the heart of NEHO is the idea of exploiting the rich electron dynamics of semiconductors. Doped semiconductors undergo an interesting transition from the size-quantization regime to the classical regime of plasmon oscillations. This transition region can exhibit strong nonlocal and nonlinear optical response due to a large variety of electron-electron interactions. The decrease in electron density induced on the semiconductor surface by an external bias can be used to modulate the nonlinear response strength. This unprecedented feature will be used to leverage the hardware implementation of a neural network into the development of new machine learning optimization techniques, including the optimization of the nonlinear activation function to different tasks. This extra degree of freedom will offer tremendous benefits for a large variety of machine learning applications.


**Keywords:** optical
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Functional genomic characterisation of molecular determinants for staphylococcal fitness, virulence and drug resistance' (STAPHDYNAMICS) targeting Sixth Framework.

assistant: **Abstract**

Staphylococcus aureus is a dangerous community- and hospital-acquired pathogen. Therefore, the spread, survival and prevalence of antibiotic resistant clones of S. aureus is an immensely important problem for human health. The selective pressure for antibiotic resistance is a driving force due to the massive use of such drugs throughout the world. However, the overall fitness and virulence of the bacteria is determined by their underlying genetic makeup. The traits, which determine the ability of a clone to become widespread, are largely unknown. These are likely to be multi-factorial, as S. aureus is widespread in the environment due to its ability to survive outside the host and to be carried as a commensal in the human nose. It is therefore crucial to determine the key parameters required for virulence, nasal colonisation and survival in the environment in order to elucidate how these combine to produce epidemic strains. This requires a detailed knowledge of the bacterial components necessary for the above processes.The StaphDynamics partnership will define these bacterial components, which in themselves may form novel targets for prevention/control. Specifically, we will investigate the fitness and epidemiology of resistant clones, characterise the most important clones phenotypically, and identify molecular determinants for fitness, virulence and resistance. To reach these goals, the full potential of bioinformatics, genomics, and proteomics approaches will be exploited. The StaphDynamics partnership has a proven track record in the application of these cutting-edge technologies and includes several of Europe's leading groups in the field of staphylococcal research. StaphDynamics will establish strong interactive links with the European Antimicrobial Resist ance Su
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Precision measurements on cold molecules in a fountain'.

assistant: **Innovation**

In a recent series of experiments, it has been shown that polar molecules can be decelerated, bunched, cooled, and trapped using time-varying electric fields. These experiments demonstrate an unprecedented level of control over molecules, which enables a variety of applications of great scientific interest. Here, I propose to use these techniques to create a molecular fountain. In this fountain, the first of its kind, polar molecules are decelerated, cooled, and subsequently launched upwards some 10-50 cm before falling back under gravity, thereby passing a microwave cavity or laser beam twice – as they fly up and as they fall back down. The effective interrogation time in such a Ramsey type measurement scheme includes the entire flight time between the two traversals through the driving field, which can be up to a second. This long interrogation time will allow for extreme precision measurements on molecular structure to a level at which fundamental physics theories can be tested. I will use the inversion frequency in ammonia around 23 GHz as a test case. This transition is very well studied and was used in the first ‘atomic’ clock and the first demonstration of a MASER. The fountain should make it possible to measure the inversion frequency with a relative accuracy of 10^{-12}–10^{-14}; that is more than a thousand fold improvement as compared to the best previous measurement. Besides serving as a proof-of-principle, this measurement may be used as a test of the time-variation of fundamental constants – an issue that has profound implications on how we understand the universe. The inversion frequency in ammonia is determined by the tunneling rate of the protons through the barrier between the two equivalent configurations of the molecule, and is exponentially dependen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Colony Personality and Pace-of-life Syndrome in Bumblebees'.

assistant: **Innovation**

Human personality is a rather self-evident phenomenon with which we are all intimately familiar. In recent years, evidence has been accumulating that personality is not only found in humans but also in a wide range of other animal species. Even if it was thought that there was no particular reason for animals to have personality, it is now recognised that consistent individual differences in behaviour could be adaptive. The pace-of-life syndrome (POLs) hypothesis predicts that individuals should differ in a suite of physiological traits that have coevolved with the life-history particularities of the species and very recent arguments suggest that differences in personality should also form integrative POLs. Yet, only very few empirical studies have shown a link between life history, immunity and behaviour within a species. This proposal aims at filling an important lacuna in the field by incorporating consistent colony behavioural traits within the POLs, using bumblebee colonies as a model system. I focus on the colony-level behaviour because 1) no work has ever addressed if and how differences in colony-level personality should form integrative POLs 2) the use of whole insect colonies will give the unique opportunity to study simultaneously the phenomenon of personality at multiple levels of individuality, deconstruct the seemingly complex colony personality into units (workers' personality) and experimentally manipulate them. I will first show if there are POLs in which colony personality covaries with colony physiology and colony life history traits. I will then delineate the underlying mechanisms leading to colony POLs analysing the role of each single bee personality in determining colony personality and its connection to colony immunity and life history. I will ex
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Preservation of historic reinforced concrete housing buildings across Europe' in the context of a Sixth Framework call.

assistant: **Objectives**

This proposal aims to show ways on how to reduce earthquake vulnerability of multiple housing construction with reinforced concrete structure of the Modern Movement, with their physical, social and cultural characteristics. These buildings have a high vulnerability due to their high degree of occupation and low capacity, as they were designed for gravitational loads only.The roots therefore lay in the fact that the type of building spread from Western Europe (early architectural typology from France and computation tables from Germany) to the earthquake prone Eastern Europe. New is the view on historical pre-code reinforced concrete buildings and also the view on historical condominium housing. To solve problems concerning the first aspect technical solutions are required, to solve problems concerning the second one-management solutions come in question. Technical issues regard retrofit measures optimisation, with special investigation of steel bracing of reinforced concrete frames.Societal issues concern the comprehensibility of the reason for the measures, in order to get user support for the retrofit strategy implementation, of central importance in case of condominium buildings. It is aimed to document the distribution and regional characteristics of buildings constituting the object of the study in Europe, information currently lacking, and to make these findings public. Of importance is the modularisation of a collaborative decision model, with modules customised for each actor involved in the retrofit measure, addressed in different ways by some of the objectives.This will be achieved taking into account a method suitable for non-measurable criteria, as cultural value and architecture societal issues are. The method is to be tried out experimentally as a student