RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'EUROPEAN SUMMER SCHOOL ON GEOTHERMAL ENERGY APPLICATIONS' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Romania, as well as other EU Member and Associated States, has significant low enthalpy (50-120°C) geothermal resources, suitable for direct heat utilisation and power generation. Properly implemented, geothermal energy is sustainable, most of it renewable, and benign for the environment. The present geothermal production stands far below the expectation allowed by the assessed potential, mainly in the Associated, but also in some Member States. One reason for this situation is the limited number of available specialists with the multi-disciplinary training required by the exploitation and utilisation of Geothermal resources. The University of Oradea has a 20 years experience in geothermal research and a 5 years experience in specialised geothermal high-level training.Objectives: - experienced researchers share their knowledge and experience with the younger generation of researchers (from Associated States mainly) - build up and/or preserve contacts between European researchers active in European and/or other countries (USA, Latin America) -specialists from consulting, engineering and manufacturing companies impart their state-of-the-art experience to the younger researchers - promote the geothermal energy as a clean renewable energy resource to invited decision-rnakers from areas with geothermal potential Content: - lectures on topics of geothermal energy in the Training Content - technical field trip - informal round table.ftp://ftp.cordis.lu/pub/improving/docs/HPCF-2000-00339-1.pdf
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Drug REpurposing with Artificial intelligence for Muscular disorderS'.

assistant: **Objectives**

According to World Health Organization, to date, fewer than 6% of rare diseases (RDs) have an approved treatment option. In the light of this observation, it appears crucial to develop disruptive approaches that allow to find treatments for multiple RDs. To achieve this goal, DREAMS will start from 5 rare neuromuscular disorders (NMD) that share common pathophysiological characteristics related to dysfunctions of autophagy and desmin disorganization. Using skeletal muscle cells derived from induced pluripotent stem cells (skMC-iPSC), DREAMS will i) identify shared biomarkers of the 5 diseases and ii) perform a high throughput drug screen on all 5 diseases. Through a first Artificial Intelligence (AI) based solution, the output of the drug screening will be used to find drug targets shared between the diseases. A second AI based solution will be used to find drug candidates (repurposable drugs and new molecular entities) for these shared drug targets. A third AI-based solution will be used to find additional diseases that could be treated through the shared drug targets, in order to extend the indications for the most promising drug candidates. Following their discoveries, the promising drug candidates will be tested for efficacy and safety in both iPSC and mouse models of the 5 NMDs and additional diseases. In parallel, DREAMS will design an adaptive clinical trial to prepare the final stages of drug development of these novel drug candidates with multiple indications. Together, these technological and conceptual innovations will allow the DREAMS consortium to i) develop therapies to treat multiple NMDs and related diseases, ii) to create a novel clinical design that generates a regulatory pathway for drugs that treat heterogeneous groups of patients suffering from RDs
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'CryoBiopsy: a bi-modal temperature sample preservation device for standardized breast cancer biopsy'.

assistant: **Innovation**

Biopsy is commonly used in medicine and clinical research for diagnosis and characterization of cancer and other diseases. Traditionally, the tissue sample obtained is preserved by fixation with formalin and analysed histologically by a pathologist. However, current advances in biomedicine make an increased use of sophisticated molecular technologies which, rather than looking at the tissue morphology, analyse changes in specific molecules active in cellular pathways (biomarkers). These technologies require tissue that has not been compromised by the traditional biopsy fixation with formalin. Sorek Medical Systems Ltd. is a 16-year-old R&D company focused on researching, developing and producing high-tech diagnostic medical devices. Sorek's objective in this project is to develop and market a device for breast cancer biopsy which optimizes tissue sample acquisition, handling and preservation. Sorek's innovative solution, unique in the market, solves the problem of sample processing standardization and generates a sample ready for biomarker analysis, among other advantages. Sorek's biopsy devices will be used by radiologists and surgeons, and by pharmaceutical companies seeking the development of biomarker-targeting drugs with the goal of improving cancer diagnostics and the practice of personalized medicine. The innovation is of critical importance to the further development of the company, as it will reinforce its position and help us grow in an area with such huge potential as breast cancer diagnostic devices. The objective of this project is to perform a feasibility study of the technical, commercial, and financial perspectives of Sorek's proprietary differential temperature preservation technology including, among others, analysis of additional R+D necessary, certif
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'European Best Practices for Endangered Language Revitalisation' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Language endangerment has become a global crisis. According to estimates only 600 of the 6,000 or so languages in theworld are ‘safe’ from the threat of extinction. In Europe we have an increasing amount of expertise in language revitalisationfor endangered languages. These are skills and knowledge that are transferable to other language revitalisation movements worldwide giving Europe the potential to be a leader in the field. However, as we develop revitalisation techniques and as they become more nuanced, sociolinguistic analysis shows those working in the field that while there have been some successes, several endangered revitalisation efforts are either failing or at least only stemming the rate of decline in speaker numbers.The proposed research will address this last issue and using both case studies and a thematic approach examine various language revitalisation efforts so as to measure their success (or otherwise) in increasing both speaker numbers and everyday users. In short it will seek to establish what is working in endangered language revitalisation, where and how, and, in an area renowned for being poorly resourced, what is not working.


**Keywords:** Language Revitalisation. Endangered Languages. Regional or Minority Languages. Linguistic Diversity.Language Planning and Policy. Language Rights. Linguistic Landscape
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'MicrobiomE-associaTEd boosters Of immune Responses (METEOR study): experimental charac-terization and clinical exploitation.' (2021-2027) targeting Horizon Europe.

assistant: **Abstract**

I became fascinated by pathogen-host interactions at the end of my PhD, working with Hepatitis C virus, and later in my first postdoctoral phase working with Influenza A and SARS-2 viruses, when I learned the OMIC technologies power. Finally, I found out about the world of microbiota-associated interactions and how Dr. Serrano’s studies unveiled these complex networks with a clinical perspective. Most microbiota studies are based on the description of the different bacterial species profiles. How-ever, the interactions between the byproducts derived from cells and bacteria can affect reciprocally to host and microbial metabolism, modifying the outcome of the disease. With my expertise on experi-mental settings, Dr Serrano’s clinical-research view, and the strong collaborations with expert partners in bioinformatics and multi-omics, for my next career step I aim to develop experimental strategies to better identify new potential therapeutic agents. Specifically, to clinically exploit MIcrobiome-associated BOosters of Immune responses to infectious Diseases (MIBOIDs) that define the nature of the host-microbiota interaction I will implement a protocol based on directed culturomics, immune stimulations assays, bacterial species description and multi-omic toolbox to characterize the functional immune profiles associated with highly protective immune responses, and data mining through a mul-tiparametric bioinformatic integration approach. We aim to test several conditions such as describing gut microbiota from different compartments, microbial communities from localized disease-related tissues, and to describe the most functionally relevant. Finally, after the production and validation of the specific candidates in vitro, this project will lead to future validation in precli
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Biomedicine international training research programme for excellent clinician-scientists'.

assistant: **Innovation**

Significant advances in clinical practice cannot be made without a thorough understanding of the disease mechanisms from laboratory benches combined with good clinical observation and knowledge of disease management from the bed side.Clinician-scientists are the only professionals who can bridge these two worlds. The clinician-scientist role started decades ago within hospitals driven by the desire to understand and cure. However, a decrease in these vocations is now threatening progress and improvement of healthcare, thereby impacting on economic competiveness worldwide. IDIBAPS, the leading biomedical research institute of Hospital Clinic of Barcelona (Spain) as pioneer in fostering clinician scientists, proposes a 60-month innovative fellowship programme called BITRECS, Biomedicine international training research programme for excellent clinician-scientists, based on excellence only. Through 2 international peer-reviewed calls, it invites 10 fellows to implement a 36-month bottom-up research project through an outgoing phase (12-18 months at any worldwide institution outside Spain) and a return phase (18-24 months at IDIBAPS), helping to make a lasting impact within the European Research Area and put the European Union ahead of the game in this crucial area of human health. BITRECS is an international, intersectorial and interdisciplinary programme. This transnational mobility scheme will boost the fellows’ professional growth through: 1) continuous career support (scientific supervision, career mentoring and support for exploiting/disseminating the results); 2) participation in scientific and non-scientific training/networking activities linked to both sectors (academic and non-academic); and, 3) sharing experiences with peers from different disciplines.IDIBAPS, wit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Supporting the ERA-NET Learning Platform: expanding application of the ERA-NET toolbox to a broader trans-national coordination community' under Seventh Framework.

assistant: **Concept**

Building on the successful first phase of ERA-LEARN, ERA-LEARN 2 will intensify its support for the implementation of streamlined mechanisms and increased mutual learning within the wider ERA-NET community.ERA-LEARN 2 will highlight the synergies between ERA-NETs and other forms of national and regional programme coordination and facilitate high-level analysis of policy related issues in the context of programme coordination and cooperation, including possible future developments of the ERA-NET scheme. ERA-LEARN 2 will help to optimise use of resources. It will provide tools for analysis and communication formats suitable for the exploitation of high-level expertise.In particular, ERA-LEARN 2 will- extend the NETWATCH online toolbox to further facilitate aligning and harmonising the structures and procedures needed for efficient and simplified joint call implementation;- upgrade the functionality of the toolbox to provide tools for analysis of the ERA-NET implementation;- enable and provide guidance for self-assessment of ERA-NET outcome;- provide guidance in setting up sustainable structures for call implementation;- investigate the potential for mergers or the creation of adequate management structures for facilitating a cost-efficient administration especially helping organisations with multiple ERA-NET commitments;- investigate routes to identification of themes and specific topics for ERA-NETs;- facilitate discussion on user expectations for the development and future implementation of the ERA-NET scheme and complementary forms of transnational cooperation.Aiming at wide acceptance of efforts and results this can only be done in a collective effort involving the whole ERA-NET community.ERA-LEARN 2 will thus help to establish a creative forum for the exchange of exp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Federated foundational models for embodied perception' to be submitted under Horizon Europe.

assistant: **Abstract**

Computer vision is beginning to see a paradigm shift with large-scale foundational models that demonstrate impressive results on a wide range of recognition tasks. While achieving impressive results, these models learn only static 2D image representations based on observed correlations between still images and natural language. However, our world is three-dimensional, full of dynamic events and causal interactions. We argue that the next scientific challenge is to invent foundational models for embodied perception – that is perception for systems that have a physical body, operate in a dynamic 3D world and interact with the surrounding environment.The FRONTIER proposal addresses this challenge by means of:1. developing a new class of foundational model architectures grounded in the geometrical and physical structure of the world that seamlessly combine large-scale neural networks with learnable differentiable physical simulation components to achieve generalization across tasks, situations and environments;2. designing new learning algorithms that incorporate the physical and geometric structure as constraints on the learning process to achieve new levels of data efficiency with the aim of bringing intelligent systems closer to humans who can often learn from only a few available examples; 3. developing new federated learning methods that will allow sharing and accumulating learning experiences across different embodied systems thereby achieving new levels of scale, accuracy, and robustness not achievable by learning in any individual system alone.Breakthrough progress on these problems would have profound implications on our everyday lives as well as science and commerce with safer cars that learn from each other, intelligent production lines that collaboratively adapt
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'eNHANCE - intention based enhancement of reaching and grasping in physically disabled people - personalized to maximize user performance' (2014-2020).

assistant: **Concept**

The eNHANCE project key objective is to symbiotically mechanically support and motivate people with motor impairments resulting from muscular or neural degeneration (e.g. stroke) to perform complex daily life tasks. Our system aims to assist the user in performing their daily-life interaction with the environment through an intelligent multi-modal adaptive interface controlled by a high performance intention detection input interface and a personalised behavioural model. The eNHANCE active support orthotics enables the users to achieve their desired movement actions, while motivating the users to maximize their own force contribution. This will maximize user performance relative to their personal capacity, and so maximize therapeutic effects. This requires a personalized mechanical support system taking into account personal behaviour in response to arm and hand support characteristics, supplementary motivational inputs provided by the system and context. Our personalized behaviour model will be constantly predicting user performance. This model is adaptively identified based on the discrepancy between observed and predicted user performance.The eNHANCE consortium provides a unique combination of European companies, knowledge and clinical institutes required to tackle this challenge. The expertise covers such diverse fields as body-mounted sensing, high-performance intention detection, machine intelligence, behavioral monitoring and modeling, dexterous mechatronic arm and handfunction support, intelligent and user-enabling daily-life care, and economical and clinical exploitation of such new approaches.The research and innovation will be driven by clinical user and industrial requirements identification and is finalized by clinical validation and industrial prototype re
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'BEST Urban Freight Solutions II' to be submitted under Sixth Framework.

assistant: **Abstract**

BESTUFS II CA is a follow-up initiative of the thematic network BESTUFS and aims to maintain and expand an open European network between urban freight transport experts, user groups/associations, ongoing projects, the relevant European Commission Directorates and representatives of national, regional and local transport administrations and transport operators in order to identify, describe and disseminate best practices, success criteria and bottlenecks with respect to City Logistics.Overall, BESTUFS II will further identify the problems and the requirements of the cities as well as of all private actors involved in urban freight and will maintain the environment for establishing policy as well as research recommendations. The most relevant and helpful findings promoted in BESTUFS II in form of guides for actors in medium sized cities together with national seminars organised in 22 countries will undoubtedly be suitable for many actors and many cities within Europe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Evaluation of ADAM-15 in atrial fibrillation' (2007-2013) under Seventh Framework.

assistant: **Objectives**

Atrial fibrillation (AF) is the most common arrhythmia in Europe affecting more than 6 million people. AF is associated with significant mortality and morbidity including an increased risk for stroke, dementia and heart failure. Thus, AF is a major healthcare burden.The pathophysiology of AF is complex and still not fully understood. Increasing data support a genetic component to AF. Genome-wide association studies (GWAS) identified genetic variants associated with increased susceptibility for AF. However, the mechanism by which genetic variants influence the risk for AF is still unknown. At one AF risk locus with many genes, the top SNP is related to transcriptional levels of the metalloproteinase ADAM-15. Since ADAM-15 can activate inflammatory cytokines and regulate extracellular matrix turnover, it is a strong candidate gene for AF.To investigate the role of ADAM-15 in AF, the candidate, Dr. Sebastian Clauss, will characterize the cardiac phenotype of an ADAM-15 knockout mouse model. Dr. Clauss proposes to seek postdoctoral training in the laboratory of Dr. Patrick Ellinor at Massachusetts General Hospital and Harvard Medical School. During his training he will acquire new skills for characterizing mice including electrocardiography, echocardiography, invasive hemodynamics, electrophysiology (EP) studies, and optical mapping. This training opportunity would be a crucial step in Dr. Clauss’ career development as it will not only expand his scientific skills it will also enable the transfer of his knowledge and experience to Europe upon his return. Finally, he will establish a mouse electrophysiology facility in Munich that will provide the basis for his future career as an independent researcher and will further increase European research excellence.