RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'EMPYREAN: TRUSTWORTHY, COGNITIVE AND AI-DRIVEN COLLABORATIVE ASSOCIATIONS OF IOT DEVICES AND EDGE RESOURCES FOR DATA PROCESSING' (EMPYREAN).

assistant: **Innovation**

EMPYREAN envisages a hyper-distributed computing paradigm, based on federations of collaborative and heterogeneous IoT devices and resources (e.g., on RISC-V) across different providers and networks. These federations, namely Associations, operate autonomously and interconnect seamlessly utilizing distributed, cognitive and dynamic AI-enabled decision-making, to balance computing tasks and data inside an Association as well as between Associations in a multi-agent manner and across central computing environments, optimizing resources and providing scalability, resiliency, energy efficiency and quality of service. An Association will constitute a trusted execution environment, while identity and data access management schemes will assure controlled access and confidentiality of data, utilizing Cluster 3 related outcomes from participating partners. EMPYREAN will also be empowered with automated tools and mechanisms for efficient data processing of AI-workloads and secure distributed edge storage. Developed technologies will also enable Associations-native application development and deployment, contributing to the entire application lifecycle and interoperability. EMPYREAN will provide open and standardized APIs, while utilizing and extending open-source platforms maintained by European companies from the consortium. EMPYREAN will demonstrate its advanced and innovative capabilities through three well-defined use cases that involve device- and data-rich applications in advanced manufacturing, smart agriculture and warehouse automation, involving AI-driven value extraction from high volume and dynamic IoT data generated by multiple sources (e.g., robots) at the edge of the network. Also, a South Korea based use case in smart factories will further showcase the benefits of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Backreaction of Financial Networks: Risk Estimation and Asset-Management' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The financial market is a relevant part of our economy.  Its crisis spread all over the countries and affect our daily life. Understanding these phenomena has become a crucial field of academic research and a holy grail for investors. In this project, I aim to study and develop models to forecast and manage the risk propagation along simplified structures called dynamical networks with particular emphasis on the morphological changes occurring as back-reaction to the risk spread.


**Keywords:** Dynamical Networks, Correlation Networks, Back-reaction
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Thematic network: strategies for regional sustainable development, an integrated approach beyond best practices' in the context of a Fifth Framework call.

assistant: **Objectives**

The proposed thematic network REGIONET will bring together scientists, professionals, policy-makers, economic and non-governmental actors with experience in the study and/or implementation of regional development plans to discuss the experiences made so far, as well as the new needs and challenges being faced. The overall objective of REGIONET is to provide an integrated approach to support the implementation of sustainable development in regions across Europe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Decoding the Molecular Logic of GPCR Signaling'.

assistant: **Innovation**

G protein-coupled receptors (GPCRs) are key to human physiology and disease, yet their signaling remains enigmatic. What we do know is that GPCRs signal by means of allosteric communication across the cell membrane, acting as logic gates that relay signals from extracellular ligands to various intracellular transducers. Nonetheless, the logic underlying GPCR signaling at the molecular level is not yet understood. This is particularly true of three key signaling phenomena: ligand efficacy, biased signaling, and allosteric modulation. In SignAlloMod, we will address this challenge and investigate the logic of transmembrane signaling through GPCRs at the single-molecule level. We will develop a new single-molecule microfluidic method that enables simultaneous measurement of transducer binding and receptor activation states, making rigorous, quantitative models of GPCR allostery experimentally accessible. This will allow us to separate, for the first time, ligand-specific from transducer-specific effects in GPCR signaling, ultimately enabling us to decode the molecular logic of GPCR signaling. We will use prototypical GPCRs to establish our approach and to study ligand efficacy, biased signaling, and allosteric modulation. The quantitative insights into ligand-specific and transducer-specific effects afforded by SignAlloMod will redefine our understanding of GPCR signaling. SignAlloMod will provide pharmacological ligand profiles with unprecedented detail, opening new horizons for drug discovery and pharmacological intervention guided by physical principles.


**Keywords:** G-protein-coupled receptors, membrane receptors, transmembrane signaling, single-molecule FRET, microfluidics, native nanodiscs
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Sustainable C-X and C-H Functionalization Catalyzed by Copper(III) Species' (III), addressing dissemination and exploitation.

assistant: **Impact**

On the basis of recent PI’s findings, this project aims to take advantage of the Cu(I)/Cu(III) redox pair chemistry to perform a wide range of copper catalyzed organic transformations under very mild conditions, i.e. aryl-heteroatom cross coupling, aryl-halide exchange, aryl fluorination, and direct C-H functionalization reactions. The development of new sustainable methodologies alternative to Pd-based ones will make a tremendous impact into routine organic synthesis procedures and into selective late-stage modification of pharmaceuticals. Pd is the metal of choice in most of aryl-heteroatom coupling reactions but toxicity and intrinsic cost are serious drawbacks for production of drugs. Cu has become a real alternative to Pd due to low cost, low toxicity and continuously increasing efficiencies of Cu-catalyzed coupling reactions. However, the mechanistic details for Cu-based processes are still poorly understood and experimental conditions are far from sustainable. Fundamental Cu(I)/Cu(III) oxidative addition and reductive elimination steps are often invoked but remained unobserved until the recent well-defined aryl-Cu(III)-halide key species reported by the PI. An initial goal consists in the in-depth mechanistic comprehension of Cu(I)/Cu(III) redox steps in a series of electronically and structurally tuned aryl-halide model systems. A subsequent goal will be the exploration of tridentate pincer-like systems in aryl-heteroatom coupling reactions with simple aryl-halides, aiming to find milder and efficient catalysts by redirecting mechanistic pathways towards the stabilization of aryl-Cu(III) species. Exploitation of Cu(I)/Cu(III) redox chemistry in direct C-H functionalization will also be undertaken. Exploration of analogous M(I)/M(III) redox chemistry with Au and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Lymphocyte microRNAs in health and disease: Understanding lymphocyte functions through the identification of microRNA target genes and exploiting serum microRNA signatures to monitor immune responses' (I-MIRNOME).

assistant: **Innovation**

Background: CD4+ T lymphocyte subsets orchestrate immune responses in health and disease. Little is known on control of T cell differentiation exerted by microRNA that affect mRNA translation. The identification of microRNA and their targets that regulate differentiation of T cell subsets may provide new therapeutic targets for immune-mediated diseases. Since microRNA are released in exosomes and circulate in blood, activities of tissue-derived lymphocytes could be assessed by microRNA signatures in the serum. We have defined microRNAs present in resting lymphocyte subsets from peripheral blood and measured lymphocyte-derived microRNAs in the serum. We have also solved important challenges for the identification of microRNA targets, the definition of signatures of activated T cells and their monitoring in the serum, which form the key topics of this application. Advancing State-of-the-Art and objectives: We will identify microRNA of CD4+ T cell subsets purified from inflamed organs and investigate microRNA target network that regulates T cell differentiation. We will exploit this knowledge to profile signatures of in vivo activated T cells and to map genes that could improve understanding of T cell commitment. We will also develop quantitative assays to monitor microRNA signatures in the serum and provide functional evidence of key genes targeted by microRNA which could be targets of immunomodulatory drugs. Significance: This application addresses important challenges at the frontiers of immunology and could lead to significant advances in immunotherapies and diagnostic tools for patients with immune mediated diseases. New ways of identifying microRNA targets and techniques to quantify microRNA signatures in the serum, could be widely applicable in biomedical research.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Workshops retain work for disabled people by introducing process technology' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

The single market is a challenge for enterprises in Europe, especially for SME's. The user organisations of this definition phase of a business best practice pilot are a sheltered workshop coming from Belgium and its German marketing and sales partner company. Since sheltered workshops have to perform two main tasks, to stay competitive and to employ people with disabilities of their country and regions they cannot move their production to low wage countries and have to penetrate new markets. In saving and creating employment, especially for people with disabilities, they respond to one of the main challenges in Europe, that of unemployment.Co-operation is the only reasonable way to sheltered workshops (and most SME's) to respond to the fast changing requirements of European markets. It is against this background that the user organisations intend to broaden their range of business activities by looking for partners on a European network of cross-organisational co-operating sheltered workshops. The first step however will be the re-engineering of the existing processes during a first six months definition phase. One of the foci of the definition phase will be to analyse the implications a network of sheltered workshops will have on the re-engineered processes.The objectives of the project can be divided into three parts: the users, the suppliers and the overall project objectives. The user organisations aim to establish new joint business, targeting sales activities on new, especially the German market, getting support in optimising the existing processes and in designing and implementing the new business processes and in using for it existing and new business technologies. The suppliers want to support the users, exploit the results of their former HICOS project, impro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Developing maximum-resolution genotype-phenotype maps using whole-genome polymorphism data' to be submitted under Seventh Framework.

assistant: **Abstract**

Although pioneered by human geneticists as a potential solution to the challenging problem of finding the genetic basis of common human diseases, genome-wide association studies (GWAS) have, owing to advances in genotyping and sequencing technology, become an obvious general approach for studying the genetics of natural variation. They are particularly useful when inbred lines are available because once these lines have been genotyped they can be phenotyped multiple times, making it possible (as well as extremely cost-effective) to study many different traits in many different environments, while replicating the phenotypic measurements to reduce environmental noise. Here we propose to continue our groundbreaking GWAS work in the model plant Arabidopsis thaliana. We will explore the limits of the approach, moving beyond marker-trait linkage disequilibrium to full sequence information. We will carry out GWAS of important life-history traits using over 1000 inbred A. thaliana lines for which nearly complete sequence information is available. The GWAS will be complemented by linkage mapping in F2 crosses to eliminate confounding linkage disequilibrium, associations will be verified experimentally, and confirmed causal polymorphisms will be added to the model in an iterative manner in order to create an increasingly refined genotype-phenotype map.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'New Deals in the New Economy', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

How are European workplaces being transformed? What kinds of new social bargains are emerging across the European Union? How are they being institutionalised? How are new workplace bargains shaped by the broader politics of sectors, regions and national economies?These questions are crucial to the future of the European ‘social model’.  The objective of this research programme is to provide answers to these questions, drawing on cross-national survey research on workplace organisation from 1995 to 2010 and selected industrial case studies in the small open European economies of Denmark, Ireland and the Netherlands.These questions also raise crucial theoretical issues. The research reformulates the core elements of the ‘Varieties of Capitalism’ framework that has dominated comparative political economy for the past decade (Hall and Soskice, 2001). It improves our understanding of the diverse organisation of capitalism in Europe, of how that diversity is rooted in politically constructed ‘pathways to the future’, and of how capitalism is constructed out of social and institutional capabilities across Europe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Ultrasonic Planetary Core Drill' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The Ultrasonic Planetary Core Drill project seeks to build a space-compatible tool that can extract samples of rock from up to 30 cm beneath the surface and then containerise them for caching or return to Earth. This tool will be developed by a consortium led by the University of Glasgow (UK) and supported by Space Systems Finland (Finland), LIDAX (Spain) and Magna Parva (UK). The University of Glasgow will provide expertise in the field of ultrasonic drilling, which is used to penetrate rock without generating large reaction forces and thus enables deployment of the UPCD from a small lander. Space Systems Finland will provide software that will enable autonomous operations of the device, which will be essential for sample preservation, LIDAX will produce a deployment system to permit highly repeatable operations, and Magna Parva will carry out the vital systems engineering functions.The focus of the UPCD project will be a field trial in an analogue site, namely the active permafrost of Alexander Island, Antarctic. This volatile-bearing rock is exceptionally Mars-like and it is a key objective of the UPCD project to extract and containerise samples with the volatiles still intact. Ultrasonic drilling with its high downhole efficiency and supported autonomous sample health monitoring, offers drilling without elevating the sample temperature, thus reducing drive-off of the compounds that could tell us so much about the history of water on other planets.These experiments will only be possible, and the results only meaningfully analysed, if we are confident that the drill site is representative of volatile-bearing rocks and that the containerised samples contain the volatiles we seek. The engineering team at the trials will be accompanied by a scientist specialising in the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Integrated solutions for pre-processing electronic equipment, closing the loop of post-consumer high-grade plastics, and advanced recovery of critical raw materials antimony and graphite' in the context of a Horizon 2020 call.

assistant: **Objectives**

The CloseWEEE project integrates three interlinked research and innovation areas for an improved, resource-efficient recycling of polymer materials and critical raw materials from electrical and electronics equipment (EEE):(1) Efficient and effective disassembly of EEE is key for high quality material fractions, separation of materials but also for reuse of components and parts. An  information system for dismantlers will be developed, accessing webbased dismantling instructions, to ease the dismantling process, reduce destruction of reusable parts and components and to allow for a deeper dismantling level for better economics of the Recycling process. (2) Developing resource-efficient and innovative solutions for closing the loop of post-consumer high-grade plastics from WEEE, for new EEE through advanced recovery of valuable plastic streams which do not have a recycling system yet, and subsequent replacement of halogenated flame retardants by halogen-free flame retardants in new EEE.  (3) Improved recycling of Lithium-ion batteries through increasing the recovery rates of cobalt and researching a recovery technology for the critical raw material graphite from those batteries.  These technology innovations in the various stages of the EEE recycling value chain are complemented by research on reusing the recovered polymer fractions in new EEE, defining product design measures in favour of an optimised recycling eco-system, embedding related product design criteria in EU policy measures and global green procurement activities. These activities will support effectively the objectives of the European Innovation Partnership on Raw Materials.


**Keywords:** Mobile ICT devices, consumer electronics, recycling, disassembly, polymers, flame retardants, PC-ABS, PPE-PS, Lithium-