RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'The genetic basis of an exaggerated sexual ornament in the stalk-eyed fly Teleopsis dalmanni' in the context of a Seventh Framework call.

assistant: **Objectives**

Stalk-eyed flies have eyes displaced laterally from the head on elongate stalks in both sexes. Males have exaggerated eyespan and this trait functions as a sexual ornament.  Evidence from the field and laboratory shows that females prefer to mate with males that have the largest eyespan. It is thought that male eyespan acts as a signal of male genetic quality, as this sexually exaggerated trait exhibits heightened condition dependent expression. Teleopsis dalmanni is emerging as one of the key model systems for studying sexual selection driven by female mate preference and features as a key species in many popular textbooks.  We will use state-of-the-art molecular techniques to measure and map genetic variation in the stalk-eyed fly, T. dalmanni. Our goal is to map genetic variation in male eyespan of stalk-eyed flies across natural populations. We will initially concentrate on a population from the Gombak valley in Malaysia as this was the source for a laboratory based study of genetic variation. We will also investigate a distantly related population of T. dalmanni, to establish whether the same set of genetic loci contribute to genetic variation in eyespan in an evolutionarily divergent population. Finally, we will cross individuals from these two natural populations to establish which quantitative genetic loci have contributed to evolutionary divergence between populations.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Developing an efficient e-infrastructure, standards and data-flow for metabolomics and its interface to biomedical and life science e-infrastructures in Europe and world-wide'.

assistant: **Innovation**

Metabolomics is an important phenotyping technique for molecular biology and medicine. It assesses the molecular state of an organism or collections of organisms through the comprehensive quantitative and qualitative analysis of all small molecules in cells, tissues, and body fluids. Metabolic processes are at the core of physiology. Consequently, metabolomics is ideally suited as a medical tool to characterise disease states in organisms, as a tool to assessment of organism for their suitability in, for example, renewable energy production or for biotechnological applications in general.We now see the emergence of metabolomics databases and repositories in various subareas of metabolomics and the emergence of large general e-infrastructures in the life sciences.  In particular the BioMedBridges project is set to link a variety of European Strategy Forum on Research Infrastructures (ESFRI)'s projects, such as ELIXIR and BBMRI.Metabolomics generates large and diverse sets of analytical data and therefore impose significant challenges for the above mentioned e-infrastructures.We will therefore develop policies to ensure that Metabolomics data is<br/>1.\tEncoded in open standards to allow barrier-free and wide-spread analysis.2.\tTagged with a community-agreed, complete set of metadata (minimum information standard).3.\tSupported by a communally developed set of open source data management and capturing tools.4.\tDisseminated in open-access databases adhering to the above standards.5.\tSupported by vendors and publishers, who require deposition upon publication6.\tProperly interfaced with data in other biomedical and life-science e-infrastructures (such as ELIXIR, BioMedBridges, EU-Openscreen).<br/>In order to achieve this, we have assembled the COSMOS (CCOordination of St
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Building Enterprises – Wireless and Internet Security in European Regions' in the context of a Seventh Framework call.

assistant: **Objectives**

Be Wiser examines organisation and technical research challenges in some of Europe’s best known RTD regions. The technology focus is on wireless internet security; while the organisational challenge is to more effectively utilise Triple Helix clusters in regional innovation processes. This approach will strengthen Europe’s position in wireless rollout and address the challenges set out in the Digital Agenda.With the rapid expansion in wireless based devices, many undertaking complex and often highly confidential transactions, the security of data transmission is increasingly important as trillions of objects are connected via the Internet of Things.The need for fully secure systems cannot be overstated in retaining the confidence of all users and to balance the requirements of Citizens, Government and Enterprises in terms of their privacy and security needs.The clusters involved in this project are both central and peripheral and have strong technological complementary skills and experience – they have varying levels of organisational sophistication in terms of how they manage their innovation processes and recognise the potential to mentor each other while working collaboratively on RTD challenges.Be Wiser will:• Analyse the regions involved and the sector addressed via triple helix clusters bringing Policy Makers, Researchers and Enterprises together to focus on innovation processes and RTD;• Develop a JAP and develop smart specialisation strategies and identify further research and product opportunities as part of broader economic development strategies ;• Deliver tangible outputs that will enhance the competitiveness of the clusters,• Seek new market opportunities for regional enterprises, especially SMEs;• Mentor all partner regions on technology, business and clus
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Multi-color and single-molecule fluorescence imaging of intraflagellar transport in the phasmid chemosensory cilia of C. Elegans' to be submitted under Horizon 2020.

assistant: **Abstract**

Sensory cilia are essential ‘antenna-like’ organelles that protrude out of many eukaryotic cells, acting as signal transducers, enabling cells to sense and respond to the external environment. The model system for this proposed study, chemosensory cilia of C. elegans are well characterised and enable the animal to sense water soluble effectors in the environment for chemotaxis. Cilia consist of an axoneme encapsulated with a signalling protein-rich ciliary membrane. The axoneme, which is a microtubule-based core structure, acts as a template for a specialised intra-cellular transport, intraflagellar transport (IFT). IFT trains are large protein complexes that mediate contacts between motor proteins (IFT kinesins and IFT dynein) and ciliary cargoes, crucial for the formation and maintenance of the cilia, with anterograde IFT trains moving outwards from the ciliary base to deliver ciliary building blocks to the ciliary tip and retrograde IFT trains moving from the ciliary tip to the ciliary base to recycle the waste products. The overarching objective of this project is to grasp the connection between chemosensory function of cilia (initiating chemotaxis), IFT and ciliary length-regulation using single-molecule imaging techniques. In order to achieve this, (i) I will develop a multi-color and single-molecule imaging toolbox to study IFT in the phasmid chemosensory cilia of C. elegans. (ii) Using the toolbox, I will obtain a mechanistic understanding of turnaround dynamics of the IFT machinery (IFT motors and components of the IFT trains), during normal IFT. (iii) A comprehensive understanding of normal IFT will enable discovery of the subtle adjustments made by the IFT machinery, and its effect on the cilia length, in response to chemical cues in the external environment.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Improving Monitoring for Better Integrated Climate and Biodiversity Approaches, Using Environmental and Earth Observations'.

assistant: **Concept**

The BioClima project, enhanced by EU-China collaboration, aims to revolutionise biodiversity and climate monitoring by merging advanced AI with ground and remote sensing data systems for deeper terrestrial ecosystem insights. It will develop harmonised monitoring systems across the EU and China, leveraging AI to refine data models and analytical pipelines for robust policy-making. The project is set to strengthen monitoring through Essential Biodiversity Variables (EBVs) and Essential Climate Variables (ECVs), and make synergies between biodiversity conservation and climate mitigation.BioClima is designed to support policy-making with scientific insights and recommendations for integrated climate and biodiversity strategies at national and international levels. Through case studies across Europe, the project's findings will be upscaled to inform EU-wide strategies, contributing to climate neutrality, adaptation, and biodiversity conservation efforts.BioClima supports EuropaBON's goals for standardised biodiversity monitoring, enhancing data integration, and fostering international cooperation.  BioClima anticipates significant increases in monitoring coverage, accuracy in biodiversity and climate change assessments, and the implementation of nature-based solutions. Furthermore, it aims to strengthen EU-China cooperation, enhancing global environmental monitoring, conservation strategies, and policy formulation.


**Keywords:** machine learning, EU-China cooperation, policy recommendations, standardisation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Microscopic calculation of fission propreties and implication on nucleo-cosmochronology'.

assistant: **Concept**

The dating of the Universe is one of the major tasks faced by modern astrophysics. In particular, nucleo-cosmochronology" aims at determining the age of the nuclides through the use of measured abundances (in old stars or meteorites) of radio nuclides with lifetimes commensurable with presumed lifetimes of the galactic disc. Such nuclides, mainly the long-lived actinides, are produced by the rapid neutron-capture process (or r-process) of nucleosynthesis. A reliable prediction of the actinide production ratios requires continuous efforts to improve the predictions of the nuclear properties involved. These concern the ground and excited state properties (nuclear masses, fission barriers and level densities) , as well as the strong, electromagnetic and weak interaction properties of all the nuclei synthesized during the r-process. These nuclei are so neutron-rich that there is no hope of being able to measure them in the laboratory. It is thus of paramount importance to make reliable extrapolations of these quantities out towards the neutron drip line. The aim of the project is to put the extrapolations on as rigorous a footing as possible by treating all nuclear aspects of the astrophysical r-process on a unified microscopic basis. This involves (i) the extension of the Hartree-Fock method, recently developed to calculate nuclear masses, to the calculation of fission barriers for all nuclei involved in the r-process, (ii) the determination of fission rates, including spontaneous, neutron-induced and beta-delayed fission processes, on the basis of microscopic models, and (iii) the analysis of the impact of the newly-derived fission rates on the r-abundance predictions, and more particularly on cosmochronological predictions ."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'European Tools and Methodologies for an efficient ageing management of nuclear power plant Cables' (2014-2020).

assistant: **Innovation**

The lifetime of existing NPPs can potentially be extended to between 60 and 80 years if safety and operability of facilities can be guaranteed. With an average of 25 000 cables for a total length of 1 500 km per nuclear power plant (NPP) unit, all organisations involved in the current and next generation of NPPs have recognised the importance of cable qualification, condition monitoring, and ageing management. Cables, especially their insulation and jacket materials made of polymers, are vulnerable to ageing degradation during normal operation and accidents and means must be established to ensure that cable ageing does not lead to unsafe operation. Latest developments in polymer ageing research have revealed important limits in current methods for estimating the lifetime of NPP cables. These are related to the lack of representativeness of accelerated ageing  and the lack of consideration of the polymer composition (e.g. fillers, additives, antioxidants) in cable ageing models. TeaM Cables will develop a novel multiscale approach for more precise estimation of the cable lifetime. The project will analyse the effects of irradiation and temperatures on cables from micro- to macroscale level, in order to develop multiscale models of ageing. Ageing in normal operation conditions and accidental conditions will be addressed. The unique multi-scale and kinetic models produced by the project will be integrated into an open access tool – the TeaM Cables tool - which will be built on the merger of a currently used European cable management tool with a cable ageing modelling tool. In parallel, criteria and protocols for on-site use of non-destructive testing techniques will be proposed. The TeaM Cables multiscale modelling approach and associated tools will allow NPP operators to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'A small, portable cold plasma device for the treatment of chronic and acute wounds.', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

terraplasma GmbH has developed a small, portable and battery-operated device – plasma care – for the treatment of chronic and acute wounds. Besides ensuring a sufficient supply of oxygen, avoiding an infection is the most important criterion to enable fast and uncomplicated wound healing. Hard-to-heal wounds have a negative impact on patient wellbeing, are challenging for clinicians to manage and are costly to the health economy. plasmaCare incorporates its innovative cold plasma technology where plasma care will allow for a disruptive wound therapy that can save healthcare costs by facilitating early discharge from hospital, reducing wound dressing frequency (e.g. nursing time) and promote faster healing processes.terraplasma’s ambition is to reach the European market in 2020 with the innovation project boosting their efforts to fulfil this strategy: results of clinical studies on plasmaCare and their dissemination through the European network of skin specialists will be crucial to gain traction among patients, and healthcare providers in order to achieve the new product acceptance among customers and ultimately, their trust.Incorporated in Germany in 2011 and maintaining its core business in Europe with an annual balance sheet of ~ €1M and a staff headcount of 9, the company has evolved along the years from a pure R&D start-up into a commercial enterprise. The proposed work in Phase 1 of the SME instrument fits into the overall terraplasma plan to reach market by contributing the financial resources needed to plan a fast, sound and wider deployment of the plasmaCare solution and the market uptake. It will also allow the SME to accomplish key feasibility activities and reduce the business risks, such as business planning, customer identification and outreach, and stron
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Identification and functional analysis of the genes involved in junctional epidermolysis bullosa: disorders affecting adhesion of epithelial cells'.

assistant: **Concept**

- To characterise the structural organisation and analyse the functional role and regulation of the genes involved in junctional epidermolysis bullosa (JEB). - To sample and diagnose JEB patients. - To identify the candidate genes and the genetic mutations involved in JEB. - To establish a correlation between the genetic abnormalities and the defined clinical JEB phenotypes. - To extend the prenatal diagnosis of pregnancies at risk for JEB to new candidate genes. - To perform the structural and functional analysis of the proteins affected in JEB. - To establish model systems useful in the analysis of the adhesion and wound healing processes in epithelia. - To develop strategies for somatic gene therapy of keratinocytes with genetic defects in multifunctional and structural adhesion proteins.The study of the pathophysiological processes which underlie the extensive epithelial-mesenchymal dysadhesion observed in patients affected by junctional epidermolysis bullosa (JEB) has set the stage for the comprehension of the mechanisms of adhesion and migration of epithelial cells. JEB keratinocytes constitute an invaluable tool to dissect the mechanisms of cell adhesion, since the different clinical manifestations of the disease appear to be linked to mutations affecting cellular receptors and their extracellular ligands. The cooperation among the five laboratories with complementary experience and expertise will permit a comprehensive analysis of the pathophysiology of junctional bullous diseases by all the possible approaches of molecular genetics, cell biology and biochemistry. Results of this research will provide a better comprehension of the mechanisms of adhesion and migration of epithelial cells and will allow : 1) The development of new diagnostic tools, and new knowled
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Laboratoire pour l'utilisation des lasers intenses' to be submitted under Fifth Framework.

assistant: **Abstract**

Description:The LULI main experimental facility is a high power multi-beam Neodymium glass laser with three experimental rooms and the state of the art instrumentation for the experiments and laser diagnostics. The laser is a six-beam system delivering up to 80 Joules per beam. The pulse duration is adjustable from about 150 ps to 3 ns, the wavelength is 1.06 µm and frequency conversion at 2 ? and 4 ? is possible. This facility is versatile in its use and has the unique capability of delivering more than 5000 targets shots per year. The experiments usually performed on LULI's main laser concern the following domains: laser-plasma interaction, fundamental physics and atomic physics of hot and/or dense plasmas, x-ray laser research, incoherent x-ray sources, laboratory astrophysics with intense lasers, material processing by laser-induced shocks.The main laser can either be used by 1 group only in the case of full facility experiments, or it can be shared by 2 groups in the case of 1-3 beam experiments. An independent ultra-intense chirped-pulse amplification laser chain (30 J in typically 350 fs, synchronised with a 50 J, 1 ns, uncompressed pulse) is available, with its own experimental room. The beam may be transported in another laboratory to be coupled to an electron accelerator. This laser system allows experiments in the domain of laser-plasma interaction in the relativistic regime, wake field particle acceleration, laser-induced nuclear physics, transient inversion x-ray lasers, new concepts in laser fusion.Application:The total amount of laser time available through the duration of the contract is 18 weeks on the Main Installation and 15 weeks on the Ultra-High Intensity line. Each fall, a Call for Proposals appears in Physics World and in Physics Today. The call