RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Cancer prevention and early detection among the homeless population in Europe: Co-adapting and implementing the Health Navigator Model' (CANCERLESS) under Horizon 2020.

assistant: **Objectives**

Cancer is one the leading causes of death in Europe in the general population with reports noting the cancer-related mortality twice as high in the homeless population. Reasons for this excess are linked to risky health behaviours as well as significant barriers experienced by homeless people when trying to access the often highly fragmented health care systems. Timely and evidence-based preventive strategies including optimizing health care pathways provide a solution to the high cancer mortality and could improve overall health outcomes in this underserved population. The aim of the CANCERLESS project is to deliver an innovative solution as an aggregate intervention based on the combination of the tested Patient Navigator Model and Patient Empowerment Model to create the Health Navigator Model for Europe. The Health Navigator Model is an evidence-based patient-centred intervention which develops patient empowerment through health education and social support and promotes timely access to primary and secondary prevention services. CANCERLESS includes partner organizations with long-standing experience in working in the field of health and social care for the homeless in the south, east, northwest and central Europe, as well as academic institutions and local governments. Using the Consolidated Framework for Implementation as well as the Research and the Reach, Effectiveness, Adoption, Implementation and Maintenance frameworks based on implementation science know-how, the CANCERLESS project aims to reduce the gap in health inequalities for the homeless population by reducing cancer burden, which will, in turn, reduce associated costs across health and social care systems in Europe. Moreover, the CANCERLESS project aims to harness the transformative potential of the inte
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Researchers’ Night 2009 in the Czech Republic' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The Researchers’ Night 2009 in the Czech Republic wants to carry on the successful approach from the past years that attracted rather high awareness of media and thus enabled researchers to be presented to the public in an unusual way, exactly according to the goals of the European project as a whole. The partners entering this project want to play a part in changing the current public attitudes towards researchers. They welcome the opportunity to introduce researchers as ordinary people who are involved in the ordinary life the same way as the others, as well as the chance to show the public how the researchers contribute to the well-being of the society. The activities planned for the event aim will bring researchers and the public together, merging them into one, letting them cooperate and experience amusing activities together. The visitors will discover that researchers are people whose job not only is interesting and exciting but also gives results that we utilize in our everyday life. It will be emphasized that there is no need to be a genius to become a researcher, and particularly the young visitors should leave the event convinced that a scientific career could be a choice for them when they make decisions about their professional lives. To make as many people aware of the upcoming event and to communicate the message of the event also to non-comers, awareness campaign is planned for the project. The role of the European Commission in supporting this particular event will be explained and the EC will be presented as an institution that continuously and largely supports research Europe-wide.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Mechanism of u1a pre-mrna polyadenylation inhibition by u1a protein' (1994-1998).

assistant: **Innovation**

The human U1 small nuclear ribonucleoprotein (snRNP) is one of a family snRNPs that play an essential role in the removal of introns from pre-messenger RNA (pre-mRNA). The U1 snRNP-specific U1A protein autoregulates its production by binding to its own pre-mRNA and inhibiting polyadenylation. Two molecules of U1A were shown to bind to a conserved region in the 3' untranslated region of U1A pre-mRNA to produce efficient inhibition of polyadenylation. The mechanism of this regulation has been elucidated in vitro: U1A protein bound to its own pre-mRNA inhibits polyadenylation activity of poly(A) polymerase (PAP) by a direct and specific interaction between U1A and PAP.  The tripartite complex between U1A pre-mRNA, U1A protein and PAP and th relationship between its structure and function in inhibition of polyadenylation i71 vitro will be investigated. I will then experiment the possibility that the U1APAP interaction used in autoregulation of U1A protein synthesis might also be involved in either the other example of U1A regulation of polyadenylation (of SV40 late mRNA) or in the coupling of splicing and polyadenylation that has been shown to exist.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Twinning for excellence in TEsting new generation PV: Long-term STAbility and field REliability'.

assistant: **Objectives**

TESTARE aims to stimulate excellence and innovation capacity at the DegradationLab of University of Cyprus (UCY) in the topic of new generation PV technologies from the perspective of long-term stability and field reliability testing. To this end, UCY will link effectively with internationally-leading research institutions, namely Interuniversity Microelectronics Centre (IMEC), Fraunhofer Institute for Solar Energy Systems (Fraunhofer), and Ben-Gurion University (BGU). The project is put in place in order to bring UCY up to par with such excellence-intensive institutions by overcoming its weak points (lack of critical mass of scientists, networking, advanced metrology technical skills) to take its work on emerging PV testing to the next level. Activities will include knowledge transfer, exchange of best practices between UCY and leading partners, industrial networking, infrastructure sharing. The knowledge transfer will be achieved through in person training, staff/student exchanges, webinars, thematic workshops, and PhD scientific schools. To demonstrate the value of the twinning exercise and at strengthen the engagement of the partners, an exploratory research project will also take place to assess the performance and lifetime of perovskite on silicon tandem modules. This will entail close interactions between the partners including round-robin test campaigns and inter-comparison measurements towards developing new test and aging protocols for this technology. TESTARE will also focus on enhancing research management and administration capabilities at UCY in order to improve and make more sustainable its research ecosystem. This project will entail benefits for all institutions involved including the leading partners who will also gain access to new markets in MENA reg
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Innovation Technology Rating - system and digital hub'.

assistant: **Innovation**

The InnoTechRate project aims at reducing information asymmetry and cognitive biases between innovators and private and public funders on the evaluation of innovations. This will strengthen the capacity of the European innovation ecosystem to support innovative deeptech start-ups, through a better identification of high potential projects in relation to risks, and allocation of resources to highly innovative projects.In this perspective, the InnoTechRate project will adapt technology rating tools already developed by The Innovation Loop and embed them on a digital platform. This digital platform will be designed as a hub, linking project holders, investors, intermediary organisations and experts. This platform will allow project holders and investors to perform a technology rating of innovation projects in a simple and fast way.The technology rating system will be 100% data driven and will be powered by artificial intelligence. This will allow the objectiveness in the collection, the checking and the analysis of all data related to innovation projects. A link to traditional financial rating will be explored. A free and on-line version of technology rating tools will be made available.The InnoTechRate project will also develop a reference framework for the technology rating of innovation projects based on a consensus of European stakeholders and integrating the European societal and environmental challenges. This common reference framework should be common for project holders and investors. It holds the ambition to become an accepted standard and norm within the European innovation ecosystem.


**Keywords:** Technology Rating , Artificial Intelligence, Innovation , Innovation Hub
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Photonic Crystals Based on Opal Structures'.

assistant: **Objectives**

3-dimensional photonic crystals realised using a template method will be designed fabricated and characterised for their photonic band structure in the search for a full photonic band gap material. Artificial opal structures and their inverted counterparts will be in filled with semi conducting and polymer materials by a variety of techniques depending on the material used. The design of these structures is supported by a strong theoretical basis. Some applications require a full photonic band gap and others do not. Four device classes are to be investigated. These are: an optically readable elastometer, optical guiding devices, light emitting devices and theoretical model for optical disperse devices.3-dimensional photonic crystals realised using a template method will be designed fabricated and characterised for their photonic band structure in the search for a full photonic band gap material. Artificial opal structures and their inverted counterparts will be in filled with semi conducting and polymer materials by a variety of techniques depending on the material used. The design of these structures is supported by a strong theoretical basis. Some applications require a full photonic band gap and others do not. Four device classes are to be investigated. These are: an optically readable elastometer, optical guiding devices, light emitting devices and theoretical model for optical disperse devices.OBJECTIVES1. To control structural properties of opal matrices prepared from colloidal suspension using sedimentation and annealing as templates for photonic crystals;2. To control mechanisms of opal modification with respect to the photonic band gap effect by loading with semiconductors and/or polymers loaded with dye molecules and rare earth ions using both wet/vapour chemi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Phosphate and crop productivity' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

This proposal aims at genetically engineering major EU crops to improve their phosphate efficiency in order to maximise their yield potential. This relates to their ability to acquire phosphate from the environment, as well as to optimise the utilization of phosphate on the organismic, cellular, subcellular and molecular levels. This will ultimately lead to the generation of crops producing high yield with a lowered input. In order to accomplish this, a multi-disciplinary approach is chosen to devise means enabling the targeted manipulation of phosphate efficiency. Mainly potato as a model crop plant will be used to assess diverse strategies for their feasibility. Phosphate acquisition efficiency will be manipulated through enhancing the capacity of the root system to secrete protons or organic acids, to release phosphate from organic compounds or to acquire carbon from other organs in order either to enlarge the root surface, or to enhance carbon flow into the symbiont in a mycorrhizal interaction. Furthermore, other plant genes, specifically expressed during phosphate starvation, will be isolated and subjected to a functional analysis in transgenic plants in order to devise novel means to engineer plant phosphate acquisition. Phosphate utilization efficiency is subject to manipulation on the phosphate distribution within the whole plant, as well as on the cellular, subcellular and molecular level. It is envisaged to clone genes responsible for the translocation of phosphate from the roots into the shoots, and to overexpress these in transgenic plants in order to enhance translocation capacities. Furthermore, the study of transgenic plants, where major pools for phosphate storage have been removed, will give some detailed insights into the regulation of phosphate distr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The informal economy in the eu accession countries: size, scope, trends and challenge to the process of eu enlargement' (INFOREC) under Fifth Framework.

assistant: **Objectives**

The project includes the organization of a round table in Sofia in 2002. It will bring together academics and experts from governments, NGOs and private business both from EU member states and accession countries to consider the nature of the phenomenon and its domestic and cross-border implications. The speakers will present studies of the informal sector based on one or more of the existing approaches for measurement ; they will come up with conclusions about the pros and cons of the different assessment methods. The likely impact of the EU enlargement for the informal sector in Europe will be analysed; future research agenda and policy recommendations with regard to monitoring the informal economy will be outlined. On the basis of the results of the round table future research and dissemination projects of a larger scale will be initiated, including the launcher a network for future monitoring and analysis of the informal economy in Europe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Measure of Alkaline Phosphatase Activity of Plankton: An Integrated Microfluidic Approach' in the context of a Horizon 2020 call.

assistant: **Objectives**

Climate change is affecting the hydrodynamics of the world’s oceans and lead to an increase of the ocean stratification. This ocean stratification tends to trap phytoplankton in the nutrient depleted surface layer. To survive to this extreme environmental condition, some phytoplanktons can activate a set of enzymes (such as alkaline phosphatase) and use the dissolved organic matter as a nutrient source. Although measurement of the alkaline phosphatase activity can be performed with accuracy, no existing method can follow in real-time and at the single cell level the physiological adaptation such as the release of alkaline phosphatase by phytoplankton. As a consequence, no experimental evidence can directly link the alkaline phosphatase enzyme activity found in a sample to an individual. In this context, we plan to develop a new complete microfluidic system in order to better examine which species release alkaline phosphatase, in which extend and how the environmental conditions predicted in the future (Temperature and CO2) modify this enzymatic activity. This new microfluidic system will integrate in a same chip, a screening procedure based on the cell morphology, an incubation system, and an enzyme assay at a single cell level. Measurements of the kinetic of alkaline phosphatase will be performed by using two enzyme labelled fluorescence methods and time-lapse analyses.Three main results are expected from this project. Firstly, the microfluidic device will be capable to encapsulate a wide spectrum of plankton species in single microenvironment. Secondly, the development of the automatic identification system based on the new image processing algorithm will create an easy method to classify planktons depending on their morphologies. This method could be purposed as valu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Targeted DISCOvery of novel cellulases and hemicellulases and their reaction mechanisms for hydrolysis of lignocellulosic biomass' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The aim of the proposed DISCO project is to develop more efficient and therefore more cost-effective cellulosic and hemicellulosic enzyme tools for the enhanced hydrolysis of pre-treated lignocellulosic biomass in simultaneous saccharification and fermentation (SSF) conditions for bioethanol production. The focus will be on enzymes having increased catalytic activity on various types of relevant European lignocellulosic biomass. In addition enzymes with lower affinity for lignin shall also be developed. Such enzymes would increase the effective amount of cellulases/ hemicellulases for cellulose hydrolysis. Furthermore the recycling of these enzymes would be applicable. The approach in this proposal is to discover the desired activities by combining classical and modern screening technologies. The enzymes will be produced in suitable host systems for industrial enzyme production.  The project also focuses on elucidation of enzymatic hydrolysis mechanisms, about which there is a paucity of knowledge. The project will determine the limiting structural factors in these mechanisms by characterisation of the substrate during the course of the hydrolysis and the remaining recalcitrant residue. Synergy between different cellulase and hemicellulases components will also be addresses on the chosen lignocellulosic substrates. Furthermore, the project seeks to demonstrate the proof of concept with the cellulolytic enzymes in a pilot scale using the most relevant European feedstock pretreated wheat straw and related high-volume co-products.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Pushing boundaries: Innovating ultrafast ultrasound imaging to explore genotype-phenotype interplay in young hypertrophic cardiomyopathy – Real-time diagnosis and personalized management'.

assistant: **Innovation**

Hypertrophic cardiomyopathy (HCM) is the most common form of cardiomyopathy, affecting 1 in 500 individuals globally. When HCM presents in childhood, adolescence, or early adulthood (0-30yo), it carries a high risk of morbidity and mortality, threatening young lives. Notably, HCM is a leading cause of sudden cardiac death (SCD) in adolescents and young adults without prior warning – a devastating condition affecting over 8000 European youths per year.Despite genetic advances, this knowledge has yet to prevent HCM progression or major complications like arrhythmias, stroke, heart failure, or SCD. Early prediction of adverse outcomes is crucial to identify patients who may benefit from advanced therapies like implantable cardioverter-defibrillators (ICD) and heart transplantation.5D ULTRAFAST-HCM will develop new biomarkers using advanced ultrasound to address the limitations of 2D ultrafast ultrasound imaging (UUI) in capturing the heart's complex 3D structure over cardiac cycles (4D), emphasizing the need for volumetric imaging. It will develop innovative 5D-UUI technology (4D with real-time AI-driven post-processing) for unprecedented whole-heart imaging, enabling assessment of new biomarkers. Preliminary data show that increased myocardial stiffness, abnormal fiber organization, and reduced microperfusion are key indicators in young HCM patients. We hypothesize that these factors, quantified through 5D-UUI, are directly linked to adverse outcomes. We will (i) refine 5D-UUI for clinical use, automate acquisition and analysis, (ii) validate new biomarkers predicting high-risk cases, and (iii) develop a new risk prediction model for improved ICD indication.5D ULTRAFAST-HCM will establish this groundbreaking bedside imaging technology and revolutionize patient management.