RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Modulating EB protein interactions through small molecules'.

assistant: **Objectives**

Microtubule plus-end tracking proteins (+TIPs) comprise a structurally and functionally diverse family of modular proteins that preferentially accumulate at microtubule (MT) growing ends. There, they regulate MT dynamics and mediate the anchorage of MTs to many other different cellular structures to control fundamental cellular processes including cell division, intracellular transport, cell adhesion and motility, and cell organization. +TIPs have a remarkable ability to form dynamic networks where most of the protein-protein interactions are mediated by End-Binding (EB) proteins. EBs are master regulators of all known +TIP networks; they are able to autonomously track MT tips independent of any binding partner while the rest of +TIPs generally require EB to efficiently track MT ends. Recently, a short linear sequence motif, denoted SxIP, used by numerous +TIPs for localization to MT ends in an EB-dependent manner, has been demonstrated to act as a general MT tip localization signal.The proposed research aims to obtain mechanistic insights into +TIP molecular recognition mechanisms and their modes of regulation, necessary to understand how +TIP dynamic and transient interactions translate into cellular functions. A major focus of the research project involves the identification of small-molecules that modulate these interactions and serve as a biological tool that  allow the dissection with precise temporal control of the functional interplay between EBs and the broad number of proteins carrying a SxIP MT-tip localization signal. Furthermore, given the crucial role of this interplay in essential cellular processes, deregulated in neoplasia, such as MT-dynamics, mitosis or cell adhesion, and the proposed oncogenic roles of EB proteins, this research might also spur devel
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Fuel cell energy systems standardised for large transport, busses and stationary applications (FEBUSS)' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

So far, the passenger car industry has been the driving force for guiding the fuel cell designs, making the existing ones, only suitable for passenger car and residential or portable applications. In this process of development, the stack has been developed solely as being the more challenging item, then the balance of plant was added to make the Power Module with sometimes non - suitable specifications with the application. For other markets than the passenger car industry, these specifications are not suitable. The aim of FEBUSS is to develop a standardized Direct H2 PEMFC Power Module including the current converters with specifications validated by end users of the transport and stationary sectors and emphasizing the efficiency, the production and operating costs. The project will also propose an amendment of the EIHP draft proposal for the certification of fuel cell power modules.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Strategies for the Exploitation of Anchors for FLoating Offshore Wind Energy Reaping' under Horizon 2020.

assistant: **Concept**

Actively taking part to the debate on the future energy supply in Europe, SEAFLOWER proposes strategies to exploit anchor foundations for floating offshore wind turbines. Effective solutions can be drawn from the offshore oil and gas industry, where they have been made available over the last three decades. Offshore wind energy developments have distinct requirements on anchoring systems, and a systematic study to aid with a rational transfer of technology between the two energy sectors has not yet been undertaken. SEAFLOWER focuses on this, through a Finite Element (FE) study built on a rich database of consistent experimental evidences. To account for the uncertainties intrinsic to any offshore foundation problems and any technology transfers, an innovative probabilistic framework is used, using meta-modelling techniques. The objective is to define a numerical procedure that can store past experience on anchor foundations and make it available to the needs of the floating offshore wind market. SEAFLOWER addresses the actual phase of FOWT pre-commercial development and the procedure overall contributes towards overcoming the actual technical barriers to the deployment of offshore wind in deep waters. The research builds on the collaboration of internationally renowned institutions: the Centre for Offshore Foundation Systems, University of Western Australia (COFS, outgoing, Supervisor Christophe Gaudin), the National Institute for Environmental Science and Research, Université Grenoble Alpes (IRSTEA, secondment, supervisor Franck Bourrier) and the Department of Civil, Chemical, Environmental, and Materials Engineering, University of Bologna (DICAM, return, supervisor Laura Govoni). With SEAFLOWER, through continuous research and training, the experience researcher also
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Flume study of flood history effects on sediment entrainment and transport in gravel-bed rivers' under Seventh Framework.

assistant: **Concept**

Floods are among the most effective geomorphic force featuring the landscape, and also one of the most hazardous natural phenomena. The timing of flood events has a major impact on fluvial morphodynamics, river management and flood protection planning, especially under a perspective of climate change, i.e. long drought periods followed by flashy intense floods. However, the effects of different sequences of events in terms of duration and magnitude – the so-called flood history – on sediment entrainment and transport are still poorly understood, thereby limiting the accuracy of predicting fluvial adjustments and the associated flood hazards. This proposal addresses the hypothesis that the condition and structure of the river bed fluctuates with flood history in a manner that can be predicted. The overall objective of the research is to quantify the influence of flood history on the mobility and transport rate of mixed sand-gravel river beds, by means of laboratory experiments. The aim is to investigate the process by which the flow field (e.g. turbulence) and the bed structure (roughness and grain exposure/protrusion) interact as a response to an imposed flood history.  Multiple flood sequences will be simulated in a recirculating flume facility complemented by a state-of-the-art suite of monitoring equipment. The instrumentation will enable an integrated, high-resolution detection of both temporal and spatial dynamics of fluid flow (PIV and ADV techniques), sediment flux (bedload traps and image analysis), and bed topography adjustment (laser scanner). Once the physical processes at play will be understood, new empirical models will be developed to make incipient sediment motion and bedload rate prediction more accurate of the ones now available, being capable of inclu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Hypersonic Morphing for a Cabin Escape System' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Passenger safety is one of the main drivers for the development of future trans-atmospheric transportation systems. The high levels of energy associated hypersonic flights as well as the level of reliability of the enabling technology leads to the need of a passenger escape system in case of flight abort.The implementation of a cabin escape system for a hypersonic aircraft is challenged by the integration within a larger structure, the load factors for the passengers, the ejection propulsion concept, the capability to withstand extreme thermal environment(plasma flow)and the adaptability to a wide range of abort scenario conditions (low and high speed and altitude).This multi-phase nature of the return flight makes morphing an attractive solution for a hypersonic escape system. The abort scenarios cover a wide range of flight conditions and the integration within the mother spacecraft requires compact solutions in terms of shape (ex: capsule adapted to outer mold line). Thus a single shape cannot provide adequate performances and consequently it can be challenging (ex: load factors) for the wellness of the ordinary passengers expected in the cabin. The increase of the lifting capability after ejection of a escape capsule and the increase of aerodynamic control surfaces is a strong requirement in order to safely return to ground the crew – composed by non-trained persons.The main goal of HYPMOCES is to investigate and develop the technologies in the area of control, structures, aerothermodynamics, mission and system required to enable the use of morphing in escape systems for hypersonic transport aircrafts. A large cabin escape system able to change its shape and automatically reconfigure during an abort event after ejection will balance the compromise between the constr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Development of an Equipment to Monitoring and Control the Quality o f Resistance Welding' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

The main expected deliverables were 2 prototypes able to work under industrial environment, which would comprise the integration of electrical sensing and acoustic emission technologies, and a software program where a quality algorithm would be implemented. Specifications of the prototypes as well as working manuals were also expected as deliverables.Actually 2 prototypes able to work under industrial environment were developed. The prototype system is able to monitor and control the electrical, force and acoustic parameters of the resistance welding process and give a prediction of the weld spot quality in terms of its shear stress or point diameter The analysis of the relationship between process parameters and product quality features is done through a quality algorithm integrated in the system software. The prototypes have similar capabilities although its hardware basis presents some differences. It can be concluded, in general terms, that the final outcome remained substantially as originally planned. In more detailed terms, it can be said that the prototypes development was an evolution process, since the original specifications were updated during the 28 months of project duration to comply with industrial requirements and technological developments. A learning module was also developed in order to teach the system to analyse and evaluate the quality of the production.The resistance welding processes is widely used in different industrial sectors for several years due tc the high productivity rates and economical assembling process achieved for metal joining in particular. Although technical developments have been achieved in the last years concerning the process technology, the quality control of the welds produced has not yet been completely dominated. In fact
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Analysis and prediction of submarine dune dynamics' (DUNAMICS).

assistant: **Concept**

Submarine dunes pose a significant risk for offshore activities in coastal areas, especially for the growing development of European renewable marine energy. Their evolution is still poorly understood due to their complex non-linear behavior. DUNAMICS propose to fill this knowledge gap by putting forward an innovative methodology combining several fields of investigation. DUNAMICS pursues three correlated research objectives: understand the physical process that leads to subaqueous dunes equilibrium and control their geometry, study in situ deep water dunes in coastal waters of New Zealand, and develop an operational tool for prediction of submarine dune dynamics. To achieve these goals, an innovative methodology has been thought of, leaning on state-of-the-art numerical models, innovative instrumentation methods, and cutting-edge laboratory flume experiments. DUNAMICS is a collaborative research project supported by a highly skilled and complementary international team. My experience in bedform morphodynamics, added to Giovanni Coco’s outstanding knowledge in sediment patterns and numerical modelling, Heide Friedrich’s great experience in conducting flume experimentations, and Rolf Deigaard world reckoned expertise in sediment transport problems, give DUNAMICS strong basis to achieve its goals. Moreover, our complementarity will lead to a continuous knowledge sharing process between us that will also be highly profitable for the beneficiary institution. The world class brand new infrastructures of the University of Auckland (UoA) -outgoing phase- and of the Danish hydraulic institute (DHI) -returning phase- insure an exciting collaborative and scientific environment. There, I will be encouraged to deliver outstanding research, improve my scientific and teaching skills,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Revolutionising allergies diagnostics with the next generation of ultra-sensitive highly multiplexed diagnostic tests based on micro-pearls' under Horizon Europe.

assistant: **Concept**

The WHO predicts that half of the European population will suffer from allergies. Allergies are a growing burden for our society, our healthcare system and companies that have to take staff off work due to disabling symptoms.Thanks to fluorescent µpearls and the discovery of Quantum Plates, Nexdot is developing a highly multiplexed diagnostic test that will allow to assay IgE on 500 allergens (and up to 1000) at once using only one drop of blood. This innovation will revolutionize the way allergies are treated by reducing drastically the time to diagnostic and its associated cost (x10-20 reduction).Our technology could also be extended to serology tests, for detection of patient’s antibodies against infectious agents or cancer markers. It can be extended for global health for the easy and cost-effective detection of antigens as infectious or toxic agents in human, animals or environment for global health, or food for industry.


**Keywords:** allergy,serology,multiplexed diagnostic,quantum plates
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'The role of the chk1 kinase in dna-structure checkpoints in cells'.

assistant: **Concept**

Research objectives and content: Research objectives: The aim of the research proposal is to elucidate the role of Chk1p in the function of DNA structure checkpoints. Understanding of those is of considerable importance and may help to provide more effective means for cancer treatment. Content: Cells must delay progression through the cell cycle in response to DNA damage. This is achieved by the action of DNA structure checkpoint mechanisms that arrest cell division in case of a problem. A human gene, ATM, implicated in DNA structure checkpoints has recently been cloned. Mutations in this gene cause Ataxia-Telangiectasia, a disease manifested by pleiotropic effects, among others a drastic increase in radiation sensitivity and the frequency of tumour development. Although the disease is recessive and relatively rare, heterozygotes, also have an increased cancer risk. A homologue of the ATM gene also exist in S.pombe (rad3). The S.pombe chkl gene product to be investigated under this proposal acts downstream of rad3. Its function is to be examined with the following approaches. ? Identification of suppressers (i.e. downstream effectors) of chkl ? Identification of effectors of the rad3- Chkl pathway: I.e. to find elements involved in mediating the cell cycle arrest in response to DNA damage ? Characterisation of the human homologue: Verification of results obtained in the genetic screen and extension in mammalian cells. Training content (objective, benefit and expected impact) objective: To gain experience in the use of yeast genetics and to further my understanding of checkpoint mechanisms in particular of DNA structure checkpoints and their interaction with the cell cycle. benefit: My PhD studies provided me with experience in cell biology and biochemistry in cell cycle
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Electronic properties in the vicinity of a Mott insulator' under Seventh Framework.

assistant: **Concept**

Metallic compounds with d- and f-wave electrons in their outer-shell tend to have narrow bandwidths, and their electronic properties can be strongly affected by competing Coulomb interactions.  When the Coulomb repulsion is strong enough, the system may become a Mott insulator -- a state in which charge is localized due to the interactions.  The study of Mott insulators, and of the mechanisms by which their insulating behavior is destroyed, can give us significant insight regarding nearby metallic and superconducting states.In the first part of this proposal, I focus on the high-Tc superconducting cuprates.  The parent compound in these materials is an antiferromagnetic Mott insulator, which becomes a superconductor upon doping.  Doping also leads to spatial inhomogeneity at the nanostructure. I will study the effects of spatial inhomogeneity on the bulk electronic properties, as well its relationship to the superconducting temperature Tc.In the second part of this proposal, I consider itinerant electron systems on geometrically-frustrated lattices.  Geometric frustration helps suppress the formation of magnetic order, and can lead to ``spin-liquid"" states -- Mott insulators with no competing magnetic order.  The need to understand spin-liquid states is made more pressing by the advent of newly developed insulators on geometrically-frustrated lattices.   I will focus on two related systems:a) Recent experiments on the hyperkagome compound Na4Ir3O8 demonstrate a pressure-tuned spin-liquid to metal transition in a three-dimensional system. I will study the nature of such a transition and also study the possible existence of a spin liquid phase with spinon pairing in this compound.b)  Motivated by experiments on FeSc2S4, I will study the effects of orbital degeneracy on t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Stars, plANets, and Discs in multiple Systems'.

assistant: **Innovation**

Protoplanetary discs behave as astronomical wizards that turn small sand into planets. Although no magic is involved, the process of planet formation remains utterly mysterious. On the one hand, it is known that the process of star formation leads to a very high fraction of binarity. On the other hand, thousands of exoplanets have been detected around single, binary and even multiple stellar systems. Therefore, we have to face it: the process of planet formation is very resilient! Understanding how planets form in multiple systems largely relies in our capacity to comprehend gas and dust dynamics in circumstellar, circumbinary, or even more exotic protoplanetary discs. This is the scientific goal of SANDS. During this fellowship, I plan to study disc dynamics using the state-of-the-art hydrodynamical code PHANTOM coupled to the highly optimised radiative transfer code MCFOST. This combination constitutes the most powerful numerical tool available to model disc dynamics in multiple systems. The work will be done within a large collaborative network of leading experts in both disc observations and theory. This will guarantee the high impact of the deliverables and the worldwide dissemination of the results obtained. The main scope of the SANDS project is to answer the following question: how are the initial conditions for planet formation affected by stellar multiplicity? By doing so, I expect to provide a comprehensive picture of disc dynamics in multiple systems. This will shed light on the fundamental process of planet formation around young stars and inform about the resulting planetary architectures.


**Keywords:** protoplanetary discs, planet formation, multiple systems, stellar encounters, stellar binaries, hydrodynamics, numerical methods, radiative transfer, syn