RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'New and Innovative Concepts for Helping European transport Sustainability' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

The NICHES project is a co-ordination action, which will facilitate the coordination of research activities of academic institutions, industry, mobility operators and transport authorities in the area of innovative urban transport concepts and will help to identify and disseminate excellent, transferable examples of innovative transport measures in the most crucial areas of urban transport. The NICHES project objectives can be summarised as follows: - enhance discussion and knowledge exchange between practitioners, experts and researchers in the field of urban transport in Europe, ensuring that different sectors will be involved (transport authorities, operators, industry, academics, and other researchers, as well as users); - provide a forum for those involved in European research activities and projects, as well as national, local and industrial initiatives in the area of innovative urban transport concepts to share their knowledge and experience; - develop an accessible document store and a knowledge base amongst urban transport experts and practitioners on innovative transport concepts, as well as integrated urban transport strategies, in which several innovative concepts are implemented in a combined way; - identify future research needs and pave the way for innovative transport concepts, meeting mobility needs in 2020; - develop a platform for capacity building (tools and content) for practitioners with guidance on developing and implementing innovative concepts in the framework of integrated urban transport strategies. NICHES will provide coordination for a wide range of innovative urban transport concepts through a combined programme of stakeholder involvement via targeted in-depth interviews, expert working groups (adopting a successful, previously adopted focu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The role of Kcnk9 imprinting in development and disease' (2007-2013) targeting Seventh Framework.

assistant: **Abstract**

Genomic imprinting is the epigenetic marking of a subset of genes which results in monoallelic or predominant expression of one of the two parental alleles according to their parental origin. In my previous work, I discovered the imprinted expression of the Kcnk9 gene in mice and humans. Kcnk9 is a member of the two-pore (2P)-domain K+ channel family and encodes for the potassium channel protein TASK-3. This family of K+ channels was already shown to play a critical role in both cell apoptosis and tumorigenesis. Furthermore, a Kcnk9 mutation in a rat strain which represents the genetic model of absence epilepsy along with the highest expression in brain indicates that Kcnk9 plays an important role in the central nervous system. The specific aim of this project is to investigate the function of the imprinted gene Kcnk9 by gene targeting in the mouse. The research plan includes a complete characterization of imprinted expression of Kcnk9 by in situ hybridization and allelic expression analysis. The Kcnk9 knock-out will be investigated whether there are significant effects in developmental and physiological processes. Furthermore, the Kcnk9 deficient mice will be examined in terms of neurodevelopmental defects.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Mapping metabolic responses to understand coexistence and community functioning' (2021-2027), addressing dissemination and exploitation.

assistant: **Impact**

The metabolism of organisms affects the productivity of populations and communities. However, the relationship between organismal metabolism and species interactions has been scarcely explored. Hence, predicting the rates at which entire communities flux energy and resources remains difficult. My work shows that the metabolism of organisms measured in isolation does not reflect their performance in communities because species interactions alter how organisms uptake and expend resources. Understanding how such interactions affect metabolism is essential to estimate productivity and how it will change with biodiversity loss and global warming. I propose to use marine phytoplankton as a model laboratory system to determine how metabolic responses to competitors affect coexistence and community functioning. My goal is to connect metabolic theory, that studies physical constraints on the metabolism of organisms in isolation, with community ecology, that centres on species interactions and emergent community properties. Based on my preliminary data, I will map metabolic responses between species that compete for similar resources and test whether these responses stabilise coexistence. I will leverage developments in transcriptomics of non-model organisms to identify the metabolic pathways that underpin metabolic responses. From this basis, I will extend my analysis on larger temporal and biological scales – I will determine how warming modifies metabolic responses and community productivity and, finally, how metabolism evolves in communities. Altogether, this project will demonstrate how metabolic adjustments influence the diversity and functioning of communities. I will use a system that is ecologically important because phytoplankton support 50% of global oxygen production.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Combining DISsimilar materials into functional large-scale and light-weight COmponents and structures', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The DISCO2030 project aims to develop two innovative hybrid manufacturing methods for joining dissimilar metal-metal and metal-polymer materials. Both proposed methods are underpinned by additive manufacturing (AM) technologies from the emerging technology families of Powder Bed Fusion (PBF) and Directed Energy Deposition (DED). DISCO2030 combines the advantages of PBF and DED to enable the manufacturing of multi-material lightweight, complex geometry components/structures that are able to operate in harsh environments. The process is expected to achieve a ≥20% lead time reduction compared to state-of-the-art manufacturing processes (such as die casting and brazing) and manufacture multi-material parts that have a 50% lower weight compared to reference products and a 30% higher performance (achieved among others by graded materials).The three use-cases to be demonstrated in the project are of high relevance to the EU economy and include a rocket engine, a marine engine and a cryogenic hydrogen tank for primary applications in the automotive sector. All components manufactured using the novel DISCO hybrid manufacturing methods will be subjected to rigid testing according to the respective industry standards.DISCO2030 is expected to generate significant impact by paving the way for the creation of new dissimilar material joining and testing standards, strengthening the EU’s leadership in AM technologies and increasing the EU’s resilience against global supply chain disruptions. Finally, DISCO2030 will contribute to the reinvention of the European aerospace, marine and automotive sectors, ultimately providing EU citizens with better, more sustainable and cost-effective transportation.


**Keywords:** Additive Manufacturing, Directed Energy Deposition, Powder Bed Fusion, Mu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Secure Cloud Identity Wallet'.

assistant: **Innovation**

With increasing mobility and Internet usage, the demand for digital services increases and has reached critical and high assurance domains like e-Government, e-Health and e-Business. Those domains have high security and privacy requirements and hence will be harnessed with various novel mechanisms for secure access. Approaches for handling the resulting variety of authentication and authorisation mechanisms include the use of digital identity and access management systems (IAM). Like other technologies IAMs follow the trend of using cloud services. This allows abstracting over used resources and enables ubiquitous access to identity data which is stored and processed in the cloud, but also results in an additional degree of complexity for securely operating IAMs. The goal of CREDENTIAL is to develop, test and showcase innovative cloud based services for storing, managing, and sharing digital identity information and other critical personal data. The security of these services relies on the combination of strong hardware-based multi-factor authentication with end-to-end encryption representing a significant advantage over current password-based authentication schemes. The use of sophisticated proxy cryptography schemes will enable a secure and privacy preserving information sharing network for cloud-based identity information in which even the identity provider cannot access the data in plain-text and hence protect access to identity data. We focus not only on evaluating and applying novel crypto-approaches for IAMs but also on implementing them in an easy-to-use way to motivate secure handling of identity data. In order to also address security, privacy and trust issues related to the used cloud platforms and services we will investigate assurance and resilience approac
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Systems Biology to Identify Molecular Targets for Vascular Disease Treatment' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Asymptomatic vascular damage accumulates for years before patients are identified and subjected to therapeutic measures. The limited knowledge on early vascular disease pathophysiology is reflected in the lack of therapeutic options. SysVasc aims to overcome this limitation by mounting a comprehensive systems medicine approach to elucidate pathological mechanisms, which will yield molecular targets for therapeutic intervention.The consortium is based on established multidisciplinary European research networks, including specialists in pre-clinical and clinical research, omics technologies, and systems biology from research intensive SMEs and academia; partners synergistically provide access to an extensive number of selected population-based cohorts and associated datasets, cutting edge modeling and simulation methods, and established cardiovascular disease (CVD) animal models and patient cohorts. The coordinated application of these tools and know-how will identify pathophysiological mechanisms and key molecules responsible for onset and progression of CVD and validate their potential to serve as molecular targets for therapeutic intervention. To this end, the consortium will also use unique resources to evaluate molecular homology between the available model systems and human disease, which will yield reliable essential preclinical research tools to explore proof of concepts for therapeutic intervention studies and ultimately translate relevant results into novel therapeutic approaches.Collectively, SysVasc will identify and validate novel biology-driven key molecular targets for CVD treatment. Major scientific, societal and economic impact is expected including, but not limited to, providing a valuable resource to further CVD research, and enhance competitiveness of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Stationary flywheel energy storage with integrated high efficiency electromechanical power conversion', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The main objective of the research is to develop a general purpose stationary flywheel for energy storage. The main tasks are to integrate the electromechanical power conversion in the flywheel construction in order to improve the efficiency and furthermore find the optimal material for the rotating wheel from a point of view of strength and cost. The system application have to be identified in a market review and weighted for the economical aspects. Especially renewable energy sources with a fluctuating energy flow, such as windpower have a need for a dynamic storage to satisfy the demand. Further secondary aspects of this technique are use of permanent magnets to improve the efficiency and avoid heating in the rotorwheel, cooling of remaining losses, dynamics, capacity and performances.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Reliable and cost-effective ceramic components for high-temperature fast-firing porcelain surfaces and gas turbines by microstructural control of o xide scales on SiC and Si3N4' under Fourth Framework.

assistant: **Concept**

Foreseen ResultsThis goal will be achieved by a unique combination of advanced characterization techniques such as high-resolution and analytical transmission electron microscopy and micro-Raman analysis, combined with scanning microscopy, X-ray diffraction, thermogravimetry and other methods. The combination of these characterization methods, including advanced techniques for sample preparation, will allow us to relate the information on the oxide scales microstructure on the meso- and nanoscopic levels to that of the material and to the exact processing conditions.The co-operation between partners drawn from companies developing new process technology (ESK, Germany; MRC, Ukraine and ISSPS, Belarus), research institutes specializing in oxidation of ceramics (University of Tuebingen), microstructural characterization (CNRS, France), mathematical modelling (IPMS, Ukraine) and end-users (ABB, Germany) will definitely bring the project to success.Ceramics are the only materials to allow component temperatures up to 1500°C in oxidizing environments, which are considered necessary for furnace linings and rollers in fast firing of porcelain and new generations of stationary gas turbines with a higher efficiency. Current linings with traditional SiC-based materials are known to have problems because of low life time. The life time limitation is due to the oxidation/corrosion damage of the materials. Such materials can not be considered for gas turbines because only extremely long lasting materials (operation times >10.000 hrs) with high reliability could be used.An improvement in fumace parts in a new generation of firing fumaces will allow more economic manufacturing of porcelain due to a shorter firing duration, less time for component changes and thus improve the competitiv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Contemporary Indigenous Performance: Resources for Cross-cultural Dialogues' in the context of a Seventh Framework call.

assistant: **Objectives**

This project develops and tests two related innovations – an interactive online exhibition and an arts consultancy service – as complementary parts of a package of cultural resources. The package is designed to make the research produced by the Indigeneity in the Contemporary World (ICW) project team accessible to the public, and, also, to stimulate new creative and educational uses of the project’s findings, in collaboration with indigenous artists, intellectuals and communities. The proposed innovations will maximize the reach and social impact of the ICW project by tapping its vast audiovisual records and international networks to foster creative dialogues among indigenous performance makers and cultural-sector workers and audiences, in Europe and beyond. The ICW team possesses a wealth of specialist knowledge about ways in which indigenous performance illuminates social and political debates on a transnational scale. Using this knowledge, the team hopes to build bridges between cultures and art forms. At a broader level, the online exhibition and consultancy service are conceived as building blocks for a new, flexible, open-access archive of interlinked multi-modal resources that will encourage users to engage with contemporary indigenous performance in dynamic ways. Performances are live and embodied, while records of cultural events exist in objects and recordings that can seem staid and unapproachable. The aim of this project is to model a unique, accessible and ethical resource platform that brings the intangible processes of performance making into dialogue with tangible records of specific events.  Our objective is to change the ways in which Europe conceives of its colonial pasts and its multicultural futures.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'DNA Adduct Molecular Probes: Elucidating the Diet-Cancer Connection at Chemical Resolution'.

assistant: **Innovation**

Bulky DNA adducts formed from chemical carcinogens dictate structure, reactivity, and mechanism of chemical-biological reactions; therefore, their identification is central to evaluating and mitigating cancer risk.  Natural food components, or others associated with certain food preparations or metabolic conversions, initiate potentially damaging genetic mutations after forming DNA adducts, which contribute critically to carcinogenesis, despite the fact that they are typically repaired biochemically and they are formed at extremely low levels.  This situation places significant limitations on our ability to understand the role of formation, repair, and mutagenesis on the basis of the complex DNA reactivity profiles of food components.  The long-term goals of this research are to contribute basic knowledge and advanced experimental tools required to understand, on the basis of chemical structure, the contributions of chronic, potentially adverse, dietary chemical carcinogen exposure to cancer development.  It is proposed that a new class of synthetic nucleosides, devised on the basis of preliminary discoveries made in the independent laboratory of the applicant, will serve as molecular probes for bulky DNA adducts and can be effectively used to study and AMPlify, i.e. as a sensitive diagnostic tool, low levels of chemically-specific modes of DNA damage.  The proposed research is a chemical biology-based approach to the study of carcinogenesis.  Experiments involve chemical synthesis, thermodynamic and kinetic characterization DNA-DNA and enzyme-DNA interactions, and nanoparticle-based molecular probes.  The proposal describes a potentially ground-breaking approach for profiling the biological reactivities of chemical carcinogens, and we expect to gain fundamental knowled
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Mammography with molecular imaging' under Sixth Framework.

assistant: **Concept**

The proposed project focuses on the development of a PET prototype dedicated to the examination of breast cancer, using a gamma ray sensor based on an innovative design and the new generation of photo-detectors and scintillating crystals. The innovative features of the PEMT (Positron Emission MammoTomography) system we propose will imply a high resolution (pushed to the physical limit), higher sensitivity and lower costs. It includes integrated analog and digital electronics through the design of an ASIC chip.The main application will be early breast cancer diagnosis and evaluation of chemotherapy response. New radio-tracer molecules will be searched for the detection and visualization of the pharmacokinetics of breast tumours, more specific than glucose (FDG) for breast cancer, and based on human amino and fatty acids. Phase I Clinical trials will be performed with the new radio-tracers. A clinical multi-centric validation will be performed for the PEMT prototypes.