RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'TELLchloroplasts - Trafficking of news on Extracellular Latest Likely danger to chloroplasts' (TELLchloroplasts), addressing dissemination and exploitation.

assistant: **Impact**

Plants have evolved a sophisticated system to perceive and transmit external stimuli to the cell interior and inform growth and defense. The host lab discovered a new pathway linking the PM to chloroplasts and regulating defence, based on inducible protein re-localization, co-opted by pathogens during evolution. Both the plant protein CALCIUM DEPENDENT PROTEIN KINASE 16 (CPK16) and the viral protein C4 from tomato yellow leaf curl virus re-localize from the PM to chloroplasts upon activation of pathogen associated molecular pattern (PAMP)-triggered immunity (PTI); from the organelle, CPK16 acts as a positive regulator of downstream defence responses, while C4 acts as a suppressor. However, the molecular and cellular events enabling and regulating protein trafficking from PM to chloroplasts remain elusive. Preliminary data in the host lab found the colocalization of C4 with SYP61- and Ara7-positive compartments upon flg22 treatment; among them, C4 colocalizes with Ara7 at the periphery of chloroplasts. Upon flg22 treatment, CPK16 was also able to form mobile dots in the cytoplasm. These results suggest that endocytosis is likely to be involved in C4/CPK16 trafficking from the PM to chloroplasts. In addition, phosphorylation regulation and N-terminal cleavage could also regulate the PM-to-chloroplast protein trafficking as evidenced by mass spectrometry analyses. In this project, I will utilize both CPK16 and C4 to investigate the molecular determinants underlying the protein trafficking from the cell surface to chloroplasts, including how proteins are transported from the PM to chloroplasts (Objective 1) and how N-myristoylated C4 and CPK16 are released from membrane compartments prior to chloroplast import (Objectives 2). By using cell biology, protein biochemistry, mol
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Hpc AlliaNce for Applications and supercoMputing Innovation: the Europe - Japan collaboration' (HANAMI).

assistant: **Concept**

A number of European leading Research Organizations (referred as RTOs hereafter) and research supporting organizations, with a long history of scientific and technology collaboration with Japan, are building a consortium for a proposal focusing on the development of joint High Performance Computing (HPC) applications for future generations of supercomputing platforms/architectures (preexascale, exascale, post-exascale) from Europe and Japan. European and Japanese research centers work together to develop and optimize applications of these methods in various scientific fields, such as material, biomedical and health (especially covid19 research, drug design …), and environmental sciences (such as climate modeling, seismology and prevention of natural disasters), and many other fields such as high energy physics, astrophysics, quantum computing, etc. The existing joint activities between the European consortium and the Japanese research institutes will bring together the required expertise to develop applications: this expertise ranges fromfundamental research and applied science for designing new models, to the optimization, development and the integration of new and ambitious workflows and models to efficiently profit from pre-exascale, exascale, post-exascale and hybrid architectures deployed or already operational in Europe and Japan.The European consortium gathered in the HANAMI proposal is willing to support and foster joint scientific teams to improve the performance and transferability of European and Japanese HPC applications by leveraging the skills and expertise of the scientific community within Europe and Japan. This consortium focuses on the HPC, AI and DA application communities, represented by the CoEs, academic and industrial organizations addressing the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Market Surveillance Action for Tyres 2015' to be submitted under Horizon 2020.

assistant: **Abstract**

MSTyr15 (Market Surveillance Action TYRes 2015) will help deliver the economic and environmental benefits of Regulation (EC) No. 1222/2009 on the labelling of tyres with respect to fuel efficiency.It will achieve this by:• Coordinating the monitoring, verification and enforcement activities of 13 Market Surveillance Authorities (MSAs) across the Single Market  and Turkey;• Improving the effectiveness of the MSAs through skills-building training, the provision of guidelines and the promotion of Best Practices.MSTyr15 will enhance the functioning of the European Single Market by ensuring that the tyres regulatory measures are effectively enforced across MS. It will deliver energy savings >105 GWh/year through removing incorrectly labelled tyres from the market.Experience and resources for enforcement have been very limited in many MS since the tyres regulations were introduced in 2009. MSTyr15 includes mechanisms for assisting the skills development of less experienced staff and their authorities, supporting the adoption of common best practices and providing budgets to cover the high costs of testing tyres to the required standards.It will coordinate market surveillance actions involving checks on in excess of 15,000 tyres. It will deliver a higher level of surveillance activities that go beyond testing. The consortium will work closely with other non-participating MSAs across the EEA though its liaison with the Tyres ADCO. Additionally, the MSTyr15 consortium will work together with an Advisory Board comprising of supply-side business, consumer organisations and environmental NGOs. The expected results are: - Adoption of best practices;- Market surveillance being undertaken in a more cost effective and consistent manner;- Increased awareness of and respect for market su
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Learning to synthesize interactive 3D models' under Horizon Europe.

assistant: **Concept**

Visualizing our surroundings and imagination has been an integral part of human history. In today's era, we have the privilege to immerse in 3D digital environments and interact with virtual objects and characters. However, creating digital representations of environments (i.e., 3D models) often requires excessive amount of  manual effort and time even for trained 3D artists. Over the recent years, there have been remarkable advances in deep learning methods that attempt to reconstruct 3D models from real-world data captured in images or scans. However, we are still far from automatically producing 3D models usable in interactive 3D environments and simulations i.e., the resulting reconstructed 3D models lack controllers and metadata related to their articulation structure, possible motions, and interaction with other objects or agents. Automating the synthesis of interactive 3D models is crucial for several applications, such as (a) virtual and mixed reality environments where objects and characters are not static, but instead move and interact with each other, (b) automating animation pipelines, (c) training robots for object interaction in simulated environments, (d) 3D printing of functional objects, (e) digital entertainment. In this project, we will answer the question: ""how can we automate the generation of interactive 3D models of objects and characters?"". Our project will include the following thrusts: (1) We will design deep architectures that automatically infer motion controllers and interaction-related metadata for input 3D models, effectively making them interactive.  (2) We will develop learning methods that replace dynamic real-world objects and characters captured in scans and video with high-quality, interactive, and animated 3D models as digital rep
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Driving manufacturing SME transformation towards green, digital and social sustainability'.

assistant: **Objectives**

Manufacturing is among the key driving forces of the European economy and their engagement is a must to achieve Green Deal goals.  greenSME project aims to drive manufacturing SME towards green, digital, and social sustainability. To achieve this main goal, the project will strength SME capacity for advanced technologies adoption to become competitive and climate neutral, maximising the benefits for all parts of society. This vision implies SMEs to develop a strategic approach to sustainability. The project vision, EU manufacturing industry sustainability shift, will be achieved through greenSME HUB which gathers sustainability awareness and industry engagement activities, ecosystem networking space and tailored advisory services to SMEs through the SME sustainability transformation pathway. ?The greenSME HUB will become a knowledge sharing area that gathers resources, activities, and stakeholders to enable the uptake of AT by SMEs for sustainability.  ?SME sustainability transformation pathway. The pathway gathers the whole process of guidance that will be given to the SMEs for their shift towards sustainability.?The SMEs that have developed a greenSME sustainability assessment will be eligible to apply for financial support. The project will dedicate a budget of 3 MEuros for supporting SMEs in the implementation of the sustainability strategy action plansgreenSME project is firmly committed with open science policy, and project exploitable result will be shared and disseminated. Project main outcomes are:  1) EU manufacturing SME sustainability Roadmap, 2) greenSME HUB.  A knowledge sharing community that gathers manufacturing ecosystem stakeholders and all the developed sustainability communication material within the project, 3) greenSME sustainability assessment to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Biodiversity, impact and control of microsporidia in bumble bee (bombus spp.) pollinators'.

assistant: **Objectives**

Bumblebee rearing for pollination is a necessary tool for farming of many crops. In spite of observations of microsporidian infections in 14 different bumblebee species, only one microsporidium, Norseman bomb, has been described from bumblebees. For production of bumblebee colonies it is essential to know the causative agents of disease for proper control. To avoid introduction of novel or non-endemic parasites into new areas or host species, it is vital to study Microsporidia in bumble bees (colonies are transported over long distances). We wish to document Microsporidia diversity in bumblebees, study cross-infectivity across species, costs they exert on their hosts and examine patterns of clad genesis between Microsporidia and their hosts. Further, we wish to develop a PCR-based tool for Microsporidia detection, document infection incidence in the field and in rearing operations and develop effective control strategies
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Off-the-Shelf Polypeptide-based Immunotherapy for Advanced Melanoma Treatment' under Horizon 2020.

assistant: **Concept**

Despite various existing drug delivery methods, the key challenge remains: how to deliver drugs to the desired site of therapeutic action to achieve best treatment outcome, while minimising side effects? This is even more challenging in cancer immunotherapy as a complex interplay of immune reactions need to be activated. POLYMMUNE will evaluate the technical and commercial viability of our novel polymeric nanocarrier platform (developed during my ERC Consolidator grant MyNano) for targeted drug delivery of a wide variety of diseases and therapeutics. As proof of concept, we will focus on immunotherapy delivery for metastatic melanoma. Globally ~132,000 new melanoma cases will be diagnosed each year and despite recent successes, only 50% of the patients respond to novel immunotherapies that are costly, while causing severe side effects. Coupling a commercially available antigen against metastatic melanoma to our nanocarrier will activate a broad immune response, resulting in an effective cancer vaccine that potentially targets different melanoma types, enabling off-the-shelf production. This dual action will lead to increased clinical benefit, which will come with less side effects and will be 5-10-fold cheaper than current treatments. Additionally, our conjugate is industrially scalable and thus overcome a major bottle neck of current nanocarrier-based medicine. We envision our platform technology to be used as a method of choice for drug delivery in many medical applications, such as cancer immunotherapy and neurodegenerative diseases. These applications are within reach, as depending on the modification, our conjugates can e.g. bypass the blood brain barrier and potentially be administered intranasally (nanogel). Our platform offers a highly attractive business case,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'SWIM Technical Infrastructure'.

assistant: **Innovation**

Single European Sky – the vision is clearly described in the European ATM Master Plan. Reaching the goals for the European Airspace is only possible with focused and extensive technical developments on European level. One of the major challenges is making sure every actor in ATM has the right information at the right time and in a consistent manner, as ATM information is the key to many concepts developed in SESAR. Extensive research was conducted in SESAR 1 under this topic called “System-Wide Information Management (SWIM)”.Our project addresses the technical infrastructure of SWIM as an enabler to the other projects. It will build on the SESAR 1 research results by integrating the aircraft on the one hand and the military stakeholders on the other hand into the SWIM infrastructure. The aircraft is an essential provider of information with regard to the flight trajectory and an information user, e.g. for meteorological information, which ensures a more efficient flight progress. Integration with the military will contribute to a more complete picture of the traffic situation. Both aspects will improve trajectory based operations and thus improve the experience for the passengers. The common runtime registry will extend the capability of the SESAR 1 SWIM design-time (static) registry by acting as a real-time directory, used to dynamically discover and connect to deployed SWIM services, suited best for the current request during operation, like the internet’s Domain Name Service. This will provide the consumers with an efficient access to the SWIM services, thus facilitating cost-effective operation.The companies involved in this project are the only ones that can deliver this kind of result. Not on their own – but as the unique cooperation between air navigation service
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Generalisation of Research on Accounts and cost estimation' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

GRACE addresses Task 3.4.1.4.8 of the SUSTDEV-2002 workprogramme: Costs of transport infrastructure use. The proposal aims to support the development of sustainable transport systems by facilitating implementation of transport pricing systems that reflect the costs of infrastructure use.Its objectives are to: undertake new case study research to address gaps in the existing level of knowledge of marginal social costs for road, rail, air and water borne transport develop and refine the methods of using transport accounts to monitor the implementation of transport pricing reform in an enlarged Europe Undertake innovative research on the issue of the appropriate degree of complexity in transport charges, provide clear guidance on the marginal social cost of the different modes of transport in specific circumstances and on simple and transparent methods for determining charges refine the use of models to address the broad socio-economic impacts of pricing reform.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Ethical and Societal Implications of Data Sciences' in the context of a Horizon 2020 call.

assistant: **Objectives**

Data-driven innovation is deeply transforming society and the economy. Although there are potentially enormous economic and social benefits this innovation also brings new challenges for individual and collective privacy, security, as well as democracy and participation. The main objective of the CSA e-SIDES is to complement the research on privacy-preserving big data technologies, by analysing, mapping and clearly identifying the main societal and ethical challenges emerging from the adoption of big data technologies, conforming to the principles of responsible research and innovation; setting up and organizing a sustainable dialogue between industry, research and social actors, as well as networking with the main Research and Innovation Actions and Large Scale Pilots and other framework programme projects interested in these issues. It will investigate stakeholders’ concerns, and collect their input, framing these results in a clear conceptual framework showing the potential trade-offs between conflicting needs and providing a basis to validate privacy-preserving technologies. It will prepare and widely disseminate community shared conclusions and recommendations highlighting the best way to ultimately build confidence of citizens and businesses towards big data and the data economy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Intelligent Hot Dip Galvanizing furnace for better energy use, low environmental impact and extended kettle lifespan' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Founded in 2002 in Brescia, Northern Italy, our company Zinco Service is an international provider in advanced technical services, consultancy and training for the hot dip galvanizing (HDG) industry.Starting originally offering zinc transfer services for companies using HDG furnaces, we, Zinco Service,  guided by our founders’ long experience as galvanizers and the technical expertise of our technicians, have become a specialist in HDG process and technology. Strongly focused on innovation, we have carried out extensive R & D in cooperation with acclaimed research institutions, this leading to the development and launch of an innovative technique for the inspection of galvanizing kettles, i.e. our Kettle Inspection Device (K.I.D.) in 2006. Today, we support our customers in 100% of their HDG management: from the inspection to the change of their HDG kettle, the furnace and burners repair, the optimization of their process. Listening to our customers’ feedback and concern on the kettle corrosion (limiting its lifetime to 5-7 years), the energy waste (the process efficiency of current furnaces is around 65%) and the environmental impact (as furnaces produce carbon monoxide, carbon dioxide and nitrogen oxides), we have been working with our partner Gimeco Impianti, a galvanizing plant and equipment manufacturer with 39 years of industrial experience, on a new “smart” furnace, called e-Furnace: by perfectly controlling the process and optimizing the overall design, we can decrease the energy used by 30% and increase the process efficiency by 25% while decreasing its environmental impact. With e-Furnace, Zinco and Gimeco will offer a 360° service as, through our partnership, we will provide the metalworking industries and more particularly the galvanizing companies with a ne