RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Structural basis for membrane protein biogenesis at the Endoplasmic reticulum by the SND pathway' (StructureSND) under Horizon Europe.

assistant: **Objectives**

One-third of eukaryotic genes encode for integral membrane proteins (IMPs) with the majority being assembled at the endoplasmic reticulum (ER) after being translated by the ribosome. The SRP-independent (SND) targeting pathway was recently identified as a new route for ER targeting and insertion of IMPs. It was found to recognise a subset of IMPs with a central transmembrane domain, yet it also serves as an alternative route to deliver a broad range of substrates to the ER when their canonical pathways are impaired. The yeast SND pathway comprises three components, SND1, SND2 and SND3. The cytosolic SND1 is a putative ribosome-associated factor and receptor for nascent IMP substrates. SND2 and SND3 are proposed to form a heterodimeric complex at the ER membrane that, together with the SEC61 translocon, mediates membrane insertion of substrates. However, direct evidence for the roles of the SND components and their physical interactions with each other and complexes such as the ribosome and the SEC61 translocon is lacking.This project aims to elucidate the molecular interplays between SND components and other targeting and insertion factors using a combination of structural biology, biophysics, and biochemistry. First, I will establish a genomic tagging system to purify SND complexes from Chaetomium thermophilum. I will integrate mass spectrometry and different biophysical tools to identify and subsequently characterise the interactions between SND components and their associated proteins involved in ER membrane targeting and insertion, or potentially other novel biological functions. Ultimately, I will solve the structures of endogenous SND complexes by cryo-electron microscopy. This work will provide comprehensive insights into how the SND complexes capture a broad ran
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Linked Irish Traditional Music Project' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The LITMUS (Linked Irish Traditional Music) project will focus on the development of the first linked open data (LOD) framework tailored to the needs of Irish traditional song, instrumental music, and dance (ITM), as well as European and non-European traditional musics primarily propagated through oral transmission. LOD connects data from within & beyond knowledge domains; LOD ontologies are specially designed to represent knowledge structures and relationships. The few existing LOD music ontologies do not adequately express ITM & other oral traditions, making LITMUS significant. Project activities include ontology development, LOD infrastructure creation, & development of a publicly-accessible LOD pilot. LITMUS will impact the larger European cultural heritage community & beyond, providing a framework for other organisations to model & publish their own similar collections in LOD; reifying latent shared properties & traits anecdotally known to exist in the folk music of countries with strong socio-historical links. The researcher is uniquely positioned for implementing the LITMUS project through her combination of depth & breadth of knowledge in ITM, research in music information scholarship, & technological skills. Through LITMUS, the researcher will gain new technical skills, apply knowledge in multiple areas, gain insight into LOD industry research; synthesize current knowledge with new approaches using LOD, & gain high-level publication & presentation opportunities, thus greatly enhancing her employability in the non-academic sector. A variety of non-academic and academic audiences will be engaged in dissemination & communication of project results through presentations, demonstrations, videos, & workshops, including interdisciplinary music audiences. LITMUS will a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Exploitation of streptomyces protein secretion for robust biopharmaceutical bioprocess development' in the context of a Fifth Framework call.

assistant: **Objectives**

A robust bioprocess to produce heterogonous proteins of biopharmaceutical relevance based on the exploitation of Streptomycin lividness protein secretion is aimed. Delivery of the key scientific and technical objectives will be secured by implementing the following elements of a Project plan:(1) Investigation and modification where required, of the specificity of the interacting target proteins and secretary machineries to improve overall secretion yield.(2) Routing of proteins of interest to the most efficient secretion pathway, including the recently discovered twin-argentine translocation pathway.(3) Investigation and optimisation of the fermentation conditions for recombinant proteins of interest.(4) Interrogation of the physiological basis of growth and productivity of heterogonous proteins within fermentation systems by DNA arrays.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Comparative structure-function analysis of the dengue virus envelope protein in complex with relevant ligands from the host', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

We propose to solve the crystal structures of the dengue virus (DV) envelope (E) protein from different serotypes in complex with immunologically relevant ligands from the human host.These will be:- Dendritic cell-specific ICAM-3 grabbing non-integrin (DC -SIGN). This molecule has been shown to be essential for entry of mosquito-grown virus into human dendritic cells.- Fab fragments from antibodies capable of neutralising one or more DV serotypes.In both cases we will be especially interested in serotype de pendent variations and their functional consequences, and will use a comprehensive range of DV field strains isolated from dengue fever patients in Venezuela in an extensive comparative study.Analysis of the crystal structures will be performed in the con text of binding studies of the ligands with both intact virus and purified E-protein from the corresponding strains. In the case of DC-SIGN the results will be correlated with epidemiological data on the relative virulence of the different serotypes.This study will elucidate the details of the key molecular interactions at the host cell surface, which occur during the primary DV infection at the site of the mosquito bite. Furthermore, it will reveal the specific antigenic determinants of the E-protein and their serotype dependence, which will be extremely valuable for the development of a safe DV vaccine.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'AN INTEGRATED APPROACH TO ENHANCE FOOD SYSTEMS RESILIENCE, ADVOCATING FOR FOOD SECURITY AND UNINTERRUPTED FOOD SUPPLY' (SecureFood).

assistant: **Concept**

SecureFood adopts an integrated, systems-thinking approach that acknowledges and embraces the complexity of food systems,addressing them as an interconnected network of actors, elements, activities, processes, infrastructures, and essential services related to the production and delivery of food. Based on this approach, it brings together, as consortium partners, multiple actors of the food supply chain itself, such as producers, food and beverages industries retailers and consumers, but also actors supporting the functioning of the supply chain, such as bulk carriers and road transport carriers. The actors network also includes Ministries and entities operating under their auspices responsible for coordinating national resilience-building efforts.The ultimate goal is to address the aforementioned food security challenges, by creating an ecosystem of scientific knowledge, collaborative processes, and digital tools. This ecosystem will provide evidence-based indications on the risks and vulnerabilities of different value chains(grain,fruits& vegetables,fish& aquaculture products,milk& dairy products)in different geographic contexts, and will contribute in a structured manner to the safeguarding of food security before and during crises, and to the reinforcement of food systems resilience.The cornerstone of SecureFood will be a Food Systems Resilience Management Framework with interlinked resilience and sustainability orientations as well as a Resilience Governance Framework that draws on collaborative principles and adopts inclusive and participatory processes to ensure successful cooperation between experts and stakeholders.The SecureFood ecosystem will be developed, tested and demonstrated for different case studies, one of which addressing a currently ongoing food sec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Civil society and the politics of global trade. Integrating democratic and gender concerns' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

In 2001, the fourth WTO Ministerial Conference launched the Doha Development Agenda (DDA) as a new policy framework on trade and development. Since then, numerous initiatives have been developed within the multilateral and regional trading systems aiming a t fostering this agenda. Notably, EU's efforts have focused on supporting capacity building to help stakeholders to participate effectively in multilateral negotiations. However, amidst these efforts few has been done to tackle the democratic and gender de fictis that at the local level are preventing an effective access of Southern counterparts in the world economy.This study contributes in this respect because:1. It brings together the literature on the North-South politics of global trade to democracy and gender concerns. Trade liberalization does not automatically lead to sustainable development and it often has detrimental effects on the most vulnerable social groups.This study contributes to draw connections between:(a) the challenges that policies of global trade have posed to emergent democracies; and(b) prevailing gender hierarchies in the South.2. The study provides an empirical study on the steps that local civil society actors have followed to revert democratic and gender deficits in the politics of global trade. It asks how precisely, these proposals can be addressed in two relevant examples of North-South interactions: the North American Free Trade Agreement (NAFTA) and the Economic Partnership, Political Co-ordination and Co-operation Agreement between the EU and Mexico (EU-MEX Agreement).3. Finally, the study provides an informed assessment on the democratic and gender impacts of free trade agreements between Northern and Southern counterparts and of local civic activism's engagement in this debate. It
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Quality-oriented software process management in small enterprises' (Q-PRIME).

assistant: **Innovation**

Due to massive growth of our software development department we need to introduce new methodologies and tools to improve the maturity of our software development processes in order to effectively increase quality standards. By using the result of the experiment, we will try to increase the maturity-level of our software-development processes from CMM-level 1.5 to approx. 2.5.THE EXPERIMENTThe experiment is subdivided into three consecutive phases. The first phase, process analysis, will be needed to identify and analyse the key - processes of our software development processes. The ARIS-methodology and the ARIS-Toolset will be used to do this. Secondly we will reengineer our main software development processes with respect to certain quality and efficiency-goals. In our experiment we will try to effectively deploy workflow-management and Configuration/documentation management tools. Due respect will not only be paid to technical issues but to organisational and people-issues as well. The level of skills of the software development staff will be raised significantly to achieve full commitment to our approach.The last phase of the experiment will be used to introduce a continuous improvement cycle. The experiment will be executed on the basis of two baseline projects: The first is a relatively small development project in the oleo chemical industry. The second baseline-project will be the development of a network-management tool kit. This second project involves 6 people over the period of approx. 12 months. To date, Prodacta employs 48 staff, 12 of them being busy in the software development department.EXPECTED IMPACT AND EXPERIENCETo successfully bridge the gap between the project procedures Prodacta practised before the experiment and the required industry-like product
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The scope for sexual selection in plants' (SEXIPLANTS) under Horizon Europe.

assistant: **Objectives**

The SEXIPLANTS project aims at providing a comprehensive empirical test for plants of the sexual selection theory, and decipher the mechanisms underlying sexual selection in plants.Sexual selection, acting through competition for the access to mates and their gametes, successfully explained numerous reproductive strategies in animals. Sexual selection typically emerges when females produce fewer numbers of larger gametes than males  a situation called anisogamy  which fosters competition among males for accessing the rare ovules. Sexual selection theory should thus be universally valid for all sexually reproducing anisogamous organisms encompassing plants. While the idea that sexual selection acts on plants is largely admitted, most predictions of the sexual selection theory remain untested in the plant kingdom. With a multi-method approach, including experimental evolution in the hermaphroditic plant Brassica rapa and comparative analyses in angiosperms, the SEXIPLANTS project asks:Q1. Testing the theory.Are fundamental predictions of sexual selection theory valid in the plant kingdom?We will empirically test key predictions of sexual selection theory regarding both male-male competition and female choice processes, and their demographical and genetic consequences.Q2. Specificity.Does the action of pollinators introduces specificity in the operation of sexual selection?We will empirically test how pollinator behaviour and density can alter sexual selection.Q3. Perception. Can plants perceive and respond to variation in their mating opportunities?We will empirically test whether plants can plastically adjust the reproductive strategies to variation in competition for access to mates.SEXIPLANTS will contribute to the development of a uniform and integrative theory of sex
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Platform for the implementation of NAIADES' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

PLATINA is a coordination and support action aimed at the promotion of inland waterway transport (IWT). The main objective of PLATINA is to support the Commission, Member States and third countries in the implementation of the NAIADES action programme. This will be achieved by providing technical, organisational and financial support for targeted policy actions and by building on strong interrelations with existing expert groups, projects and initiatives. WP1 (Markets) will raise awareness on the possibilities offered by IWT, by identifying best practices, contributing to an improved administrative and regulatory framework, and by developing a European IWT information portal. WP2 (Fleet) will support European IWT innovation by assisting in technology assessment, providing incubation assistance to speed up market transfer of innovations, raising visibility of IWT on strategic research agendas, facilitating exchange of hull-related information. WP3 (Jobs & Skills) will raise awareness on career opportunities in IWT, foster mutual recognition of qualifications, and support the implementation of harmonised education curricula. WP4 (Image) will coordinate activities relevant to the promotion of IWT at the European level, extend and deepen the existing network of promotion and development agencies and will prepare a common communication strategy. WP5 (Infrastructure) supports the creation of a European development plan for the improvement of IWT infrastructures, supports the implementation of River Information Services, as well as the inter-disciplinary dialogue on environmentally sustainable waterway development. The PLATINA consortium has ensured the active participation and support of key industrial actors, associations, knowledge institutes and Member States administratio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Earth Images Discovery  Order Shop API.' in the context of a Horizon 2020 call.

assistant: **Objectives**

We, Geocento Spain S.L. (GEOCENTO) specialise in providing products and services to exploit satellite and drone imagery. After producing our first product, EarthImages, which currently receives over 90,000 image searches per year, we now aim at developing EIDOS-API, a complete API ecosystem that not only allows the creation of powerful imagery aggregator services, but also customise end-to-end discovery and acquisition funnels. Thanks to EIDOS, we aim at becoming the reference tool to build imagery marketplaces for SMEs: a hybrid between Amazon and Google Earth for imagery that will make us boost our growth, creating 12-16 new positions & achieving ~€8-million retained-earnings by 5th year of business.We aim at (1) building an ecosystem of imagery products & services that leverage the power of the swarm rather than a single constellation of set of supplier offerings; and (2) make it simple, as just selecting the right image can be a painful experience. EIDOS addresses these SMEs pains and simplifies the integration of imagery in their businesses. Current fragmentation and lack of consensus on a standard way to request and catalogue images makes our service of the utmost relevance for SMEs needing satellite/airborne imagery on their businesses. Now we aim to take a step forward by providing 3x unique selling points:1. Effectiveness at creating imagery (meta) marketplaces.  2. Consolidation of a complete API ecosystem built with support and insights from relevant end-users (230+ clients, 60+ RFQs from 15+ markets and support of key players).  3. Collect anonymised data (from users accepting to share) on type of images, transformation and information of interest as per niche market and geography to provide cross-border/per-market statistics.