RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'DELta Virus infection in animal and human hosts'.

assistant: **Innovation**

The emergence and rapid transmission of viruses pose increasing risks and challenges to modern societies, threatening public health and economic stability. A thorough understanding of basic virology is therefore critical for an informed development of preventive and control strategies. Although for more than 40 years the only known member of deltaviruses was the human Hepatitis Delta virus (HDV), it was recently discovered that HDV-like agents are present in a variety of animal vectors and reservoirs including bats, rats, snakes, birds and insects. Metagenomic data indicate that these satellite viruses possess an unrecognized host shifting capacity enabling them to cross the species barrier. As no efficient antiviral treatment is available against HDV, the emergence of novel deltaviruses poses a significant potential threat to human health. To date, animal deltaviruses have not been functionally characterized and little is known about their basic biology. The proposed project (DELV) aims to generate essential knowledge about the biology of deltaviruses, their interactions with host cells, their zoonotic potential and evolutionary fitness. Using newly generated deltavirus molecular clones coupled to unbiased proteomic and genetic approaches, DELV will identify host factors interacting with deltaviruses in their natural animal and human hosts (Aim 1). Further, it will determine and characterize host factors that are essential for deltavirus replication in the human host when they cross the species barrier (Aim 2). Finally, DELV will discover viral elements favoring deltavirus host shifting and adaptation capacities (Aim 3). DELV aims to shape novel paradigms in virology, RNA biology and host-pathogen interactions. Knowledge generated through DELV will guide the developmen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Data Driven Dairy Decisions 4 Farmers'.

assistant: **Innovation**

The Data Driven Dairy Decisions for Farmers (4D4F) thematic network will focus on the role which dairy animal and environmental sensors can play in collecting real time information to help make more informed decisions in dairy farming.The network will develop a Community of Practice comprised of farmers, farm advisors, technology suppliers, knowledge exchange professionals and researchers who will work together to debate, collect and communicate best practice drawn from innovative farmers, industry and the research community to facilitate the co-creation of best practice.  The results will be communicated to farmers using best practice guides on the use of sensors and data analysis tools supported by videos, infographics and an online virtual warehouse of dairy sensor technologies.The network will include the development of Standard Operating Procedures (SOPs) which can be tailored to individual farms to help farmers and farm advisors adopt dairy sensor and data analysis technology.  The SOPs will be developed by working groups of the Community of Practice including farmers, farm advisors, technology suppliers, knowledge exchange professionals and researchers, who will work together to develop farmer friendly SOPs.The on line Community of Practice and published communication tools will be complimented by on farm events and workshops to help farmers and farm advisors implement innovative sensor and data analysis technologies.  The workshops and events will promote discussion between farmers and their peers on how best to use sensors and data analysis in their own businesses.  This will lead to local peer to peer support to facilitate the adoption of data driven dairy decision making.The network will work closely with EIP Agri and at member state level it will work with e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Probabilistic Inverse Models for Assessing the Predictive Accuracy of Inelastic Seismic Numerical Analyses' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

This research proposal deals with developing probabilistic inverse models for assessing the predictive accuracy of inelastic seismic numerical analyses. Numerical models for predicting the inelastic response of structures in seismic loading are biased by so-called epistemic uncertainties that arise from our lack of knowledge: modelling errors, poor comprehension of material constitutive behaviours and of the energy dissipation mechanisms, and so on. Bringing together experts in probabilistic computational mechanics, earthquake engineering, nonlinear material science and mathematical statistics, the research project aims at providing innovative useful numerical tools to researchers, designers and analysts for decision making regarding the seismic risk and structural safety of designing and existing structures. More specifically, research will be oriented toward developing deterministic-probabilistic inverse models to quantify the epistemic uncertainties in inelastic seismic numerical analyses. Such models will allow for computing confidence regions for the quantities of interest. Confidence regions reflect the predictive accuracy of the simulations and provide useful information for defining new research orientations as well as for structural safety and risk assessment.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Eco-friendly ytterbium-doped perovskite nanocrystals embedded in glasses for solar cells' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Quantum cutting down-conversion materials have emerged as a novel approach to increase solar cell efficiency by reshaping the solar spectrum. Efforts worldwide have focused on Yb-doped lead halide perovskite nanocrystals (PNCs) due to their highly efficient near-infrared (NIR) photoluminescence (PL) that matches the bandgap of the commonly used photovoltaic materials. However, two major challenges limit their commercialization: 1) the high toxicity of lead (Pb), 2) the instability of PNCs against moisture. Therefore, there is a need to develop Yb-doped Pb-free PNCs and embed them in dense structures like glass to increase their chemical stability over time. To this end, the interdisciplinary NEBULAE project aims to develop new fluorophosphate (FP) glass-ceramics (GCs) that contain Yb-doped Pb-free PNCs. It will be the first to report not only Pb-free PNCs in FP glass but also Yb-doped perovskite FP GCs for solar cells. Thus, 1) Yb-doped FP glasses will be synthesized using the melt-quenching method and characterized by a complex of spectroscopic methods to study the composition-property relation. 2) Nucleation and growth will be investigated, and heat treatment will be conducted to obtain transparent GCs with enhanced NIR PL, in which Yb-doped Pb-free PNCs are embedded in the volume of the glass. 3) The GCs will be tested in a solar cell to demonstrate proof-of-concept improvement in cell performance. NEBULAE is based on the PIs expertise in optics, the supervisors in glass science, and the co-supervisors in solar cells, ensuring the achievement of the research goals, dissemination, and exploitation of the results. The training/research activities will equip the PI with the skills needed to apply to ERC Starting Grant and/or obtain a tenure track in the EU, which will a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Architecture oriented paraLlelization for high performance embedded Multicore systems using scilAb' (ALMA).

assistant: **Innovation**

The mapping process of high performance embedded applications to today's multiprocessor system on chip devices suffers from a complex toolchain and programming process. The problem here is the expression of parallelism with a pure imperative programming language which is commonly C. This traditional approach limits the mapping, partitioning and the generation of optimized parallel code, and consequently the achievable performance and power consumption of applications from different domains. The Architecture oriented paraLlelization for high performance embedded Multicore systems using scilAb (ALMA) project aims to bridge these hurdles through the introduction and exploitation of a Scilab-based toolchain which enables the efficient mapping of applications on multiprocessor platforms from high level of abstraction. This holistic solution of the toolchain allows the complexity of both the application and the architecture to be hidden, which leads to a better acceptance, reduced development cost and shorter time-to-market. Driven by the technology restrictions in chip design, the end of Moore's law and an unavoidable increasing request of computing performance, ALMA is a fundamental step forward in the necessary introduction of novel computing paradigms and methodologies. ALMA helps to strengthen the position of the EU in the world market of multiprocessor targeted software toolchains. The challenging research will be achieved by the unique ALMA consortium which brings together industry and academia. High class partners from industry such as Recore and Intracom, will contribute their expertise in reconfigurable hardware technology for multi-core systems-on-chip, software development tools and real world applications. The academic partners will contribute their outstanding e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Bayesian inference and model selection for stochastic epidemics' (BERNADETTE), addressing dissemination and exploitation.

assistant: **Impact**

The ultimate goal of this Fellowship, titled “Bayesian infEReNce And moDel sElecTion for sTochastic Epidemics” (BERNADETTE), is to train a talented researcher through a research project focused on the development of novel statistical methodology for the modeling of infectious diseases like COVID-19. The success of the interdisciplinary project will lead to a number of multidisciplinary innovations in epidemiology, Public Health policy and statistics, which will contribute to the timely identification of optimal disease control strategies. The Fellow – Dr. Lampros Bouranis – will be trained in the fields of statistics and epidemiology, receiving access to a unique training experience at the host – Department of Statistics, Athens University of Economics and Business (AUEB) – and co-hosts. The BERNADETTE outputs will be relevant to healthcare and the EU Epidemic intelligence, by: i) offering novel statistical methodology for the analysis of COVID-19 outbreak data and the description of a number of aspects of the underlying infection pathway of the disease, ii) quantifying the effect of non-pharmaceutical interventions based on an epidemic model, iii) allowing for the forecasting of future case number scenarios, iv) contributing in the assessment of the socio-economic impact of different response strategies for human epidemics in Europe in order to improve European preparedness planning and support decision-making in the framework of national epidemic preparedness plans. The BERNADETTE outputs will contribute to the enhancement of EU scientific excellence. Additionally, the project will enable the establishment of a long-term collaboration between the host and co-hosts, bringing the centers of European research excellence together.


**Keywords:** Stochastic epidemics,  Ba
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'ADVANCED TOOLS FOR EXPOSURE ASSESSMENT AND BIOMONITORING' (A-TEAM), addressing dissemination and exploitation.

assistant: **Impact**

A-TEAM is a major co-ordinated supradisciplinary study. It seeks to develop understanding of a variety of aspects related to external and internal exposure to selected chemicals using a single, well-characterised human cohort (the “A-TEAM”). Its overriding hypothesis is that current approaches used to monitor human exposure to consumer chemicals can be substantially improved by filling gaps in scientific data and understanding upon which current practices are founded. A-TEAM’s main research goal is to further understanding of how and to what extent consumer chemicals enter humans, and of how we can best monitor the presence of such chemicals in our indoor environment, diet, and bodies. Our vision is that such enhanced understanding of the underpinning science will lead to more effective approaches to monitoring human exposure to chemicals within Europe, thereby improving assessment of risk associated both with recent and current-use consumer chemicals, as well as those under development, and leading ultimately to more sustainable approaches to the use of chemicals. Our principal objectives are to provide robust scientific information that will allow better understanding of:(1) how we can identify at an early stage, chemicals likely to accumulate in Europeans;(2) how to monitor chemicals in our external environment in a way that best reflects what accumulates in the body;(3) the relative importance of different exposure pathways to overall exposure for selected consumer chemicals of toxicological concern;(4) how contact with chemicals in our external environment translates into their presence in our bodies and how best to monitor this presenceAs well as contributing significantly to scientific knowledge; A-TEAM contributes substantially towards the training and developme
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The human retina at single cell resolution: functional architecture, disease mechanism and therapy development' (HURET).

assistant: **Concept**

Vision is of key importance for humans and losing vision has a major effect on day-to-day life. Vision starts in the retina, where an image captured by photoreceptors is processed by retinal circuits built from more than hundred cell types. Information flows from the retina via the thalamus to a number of cortical areas. Despite the large number of cortical neurons involved in vision, most blinding diseases originate in the retina and are cell-type specific. Although the vertebrate retina has a conserved cellular architecture, only a few animal models of visual diseases reproduce the pathology found in humans. Therefore, there is a major need for understanding the healthy and the disease-affected human retina. Recently my laboratory developed a set of new technologies that enable us to study the human retina, to understand its functional architecture and disease mechanism in its cell types, and so to develop therapies. Using these technologies, we first aim to describe the functional diversity as well as the function of ganglion cell types and their circuits in the human retina. Second, we aim to reveal mechanisms of cell-type vulnerability in human and mouse retinas. Third, we aim to provide proof of principle for cell type-targeted near infrared vision restoration in the human retina. Taken together, this study will provide insights into the structure, function, and mechanisms of disease of the cell types in the human visual system and will investigate a new approach to restore vision in patients with blinding diseases.


**Keywords:** retina, two photon imaging, human, optogenetics, organoid, neuronal circuit, vision
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'DropletMicroarrays: Ultra High-Throughput Screening of Cells in 3D Microenvironments' (DROPCELLARRAY).

assistant: **Concept**

High-throughput (HT) screening of live cells is crucial to accelerate both fundamental biological research and discovery of new drugs. Current methods for HT cell screenings, however, either require a large number of microplates, are prone to cross-contaminations and are limited to adherent cells (cell microarrays), or are not compatible with adherent cells as well as with spatial indexing (droplet microfluidics). We recently demonstrated the use of superhydrophobic-superhydrophilic microarrays to create high-density arrays of microdroplets or hydrogel micropads. We propose here to develop a new platform for HT cell screening experiments using the unique properties of the superhydrophilic microarrays separated by superhydrophobic thin barriers. The new technology will allow us to perform up to 300K cell experiments in parallel using a single chip. Individual cell experiments will be performed in thousands of completely isolated microdroplet at defined locations on the chip. This will enable spatial indexing, time-lapse measurements and screening of either adherent or non-adherent cells. Parallel manipulations within individual microreservoirs, such as washing, addition of chemical libraries, or staining will be developed to open new possibilities in the field of live cell studies. Superhydrophobic barriers will allow complete isolation of the microreservoirs, thus preventing cross-contamination and cell migration. We will also develop a technology for the HT screening of cells in 3D hydrogel micropads. We will use these methods to gain better understanding of how different parameters of the 3D cell microenvironment influence various aspects of cell behavior. The project will require the development of new technological tools which can later be applied to a wide range of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'URBAN MOBILITY CULTURES IN TRANSITION: SOCIO-SPATIAL IMPLICATIONS OF TRANSFORMATIVE PRACTICES' (TRANSFORM).

assistant: **Concept**

The interaction between individual choices to address mobility demands and the structural components of cities (e.g., land use and transport system) results in specific urban mobility cultures, which can be different across cities, regions, and countries. To varying degrees, those urban mobility cultures threaten various ecological, economic, and social objectives of a sustainable development. The project TRANSFORM aims to break new academic ground by studying from a holistic, interdisciplinary, intersectoral and gender- sensitive approach the meaning and functioning of transitions in urban mobility cultures, examining whether and to what extent transformative practices are effective mechanisms for activating and consolidating the transitions mentioned as well as the resulting socio-spatial effects. The operationalization of the project will be mainly based on recruiting 13 doctoral candidates, aiming to pursue post-graduate studies towards the acquisition of a doctoral degree. The research program of these individual researchers will be integrated into a set of 8 work packages that include the participation of 16 highly-reputed European academic institutions and 9 experienced non-academic organizations of relevance for urban mobility: private companies, associations, regional governments, and urban living labs. The project will focus on training of a new generation of researchers through an innovative, comprehensive, interdisciplinary, and intersectoral doctoral program that includes: (i) academic training; (ii) non-academic training; (iii) transferable skills training; and (iv) specific and coordinated supervision & mentoring.


**Keywords:** urban mobility; policymaking; governance; sustainable communities