RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'West African Middle Stone Age Timeline using ESR dating of quartz' (WATIME), addressing dissemination and exploitation.

assistant: **Impact**

The evolution of H. sapiens in Africa is intrinsically linked to the expansion of the Middle Stone Age (MSA). West Africa is one of the last frontiers for human evolutionary research and has long been considered to have played virtually no role in our species' biological, cognitive and behavioural evolution. Recently-excavated MSA sites across West African changed this perception, but there is still a critical need for reliable chronometric dates to establish a secure timeline for the MSA. While the Optically Stimulated Luminescence (OSL) dating applied to quartz has already provided some key chronological constraints, the method has also shown some clear limitations as it cannot chronologically cover the entire MSA time range.WATIME project aims to explore the potential of the Electron Spin Resonance (ESR) dating, the key alternative method to date quartz. The project is built on promising results from a pilot study at Bete I-Anyama site (Ivory Coast), which not only demonstrated the potential and feasibility of using Titanium (Ti) signals to date quartz samples from West Africa, but also led to the identification of some specific methodological issues worth investigating further to ensure the reliability of the ESR dating method. WATIME will address them by developing and quantifying and measurable accurate criteria to assess the suitability of Ti ESR signal, improving spectral resolution, measurement precision and signal characterization.Implementing a new rapid and accurate laboratory ESR dating procedure will help resolve the chronology of MSA West African sites that cannot be dated by other means. WATIME opens an innovative way to date the key changes in cultural/behavioural patterns from the archaeological record in West Africa. The results will be broadly commun
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Differentiation: Clustering Excellence'.

assistant: **Concept**

The action ‘Differentiation: Clustering Excellence’ (DiCE) establishes a large research network designed to support policy decisions on EU differentiation. This CSA creates a unique cluster of excellence by bringing together, through their coordinators, the three successful H2020 sister projects on differentiation (EU3D, EU IDEA, InDivEU), which is amplified by the involvement of the TEPSA network and a strategy for including other experts plus UNEXE. DiCE’s overarching objective is to ensure that state-of-the-art research on differentiation is properly translated into policy-relevant advice and made readily accessible to policy-makers at European, national and regional levels of governance and society, better preparing the EU for future differentiation scenarios. The open and inclusive network will become the ‘Who’s Who’ of researchers working on differentiation and the dynamics of European integration. The three projects consist of 38 partner institutions (22 universities, 15 think tanks, 1 media partner) from across Europe involving more than 50 leading scholars and experts on differentiation. TEPSA’s presence in 35 European countries further enlarges the projects’ geographical scope. DiCE pursues a number of measurable, realistic and achievable objectives that are consistent with the call’s expectation of networking, knowledge exploitation and dissemination, and impact on EU policy-making. DiCE will: (a) create a network of experts on differentiation within and beyond Europe in an open and inclusive manner; (b) undertake a comprehensive stock-taking and synthesis of research including the production of a differentiation manual and portal; (c) map, synthesize and develop future scenarios on differentiation and test them at a scenario marathon; (d) improve the sustain
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Imaging of border cell migration and receptor tyrosine kinase signalling in live Drosophila ovaries' in the context of a Sixth Framework call.

assistant: **Objectives**

The mechanism by which cells migrate is well understood in vitro but far less is known about how invasive migration occurs within a three dimensional tissue. Migration of border cells in the Drosophila ovary provides excellent model system for this. Border cells delaminate from an epithelium surrounding the germ line tissue and migrate, as an 8-cell cluster, directionally towards the oocyte. To migrate, border cells must actively invade the germ line tissue. Studying their migration may therefore provide better understanding of how cancer cells metastasise.Genetic studies have defined signalling molecules involved in guiding the migration: Two Receptor Tyrosine Kinases, PVR (PDGF/VEGF Receptor) and EGFR, act as guidance receptors. A small GTPase, Rac, and sp ecific Rac exchange factors, act downstream of the receptors. Studies of fixed tissues have also given some insight into the mechanism of migration: One border cell within the cluster initiates migration by extending a very long cellular extension (LCE) in the direction of migration. LCEs may provide the mechanical force for migration, pulling the border cell cluster towards the oocyte. What is missing for understanding the mechanism of spatially controlled guidance signalling and mechanism of movement i s to visualize these events dynamically.I propose to develop a method of culturing and imaging Drosophila ovaries in order to observe border cell migration in real time. I will observe the behaviour of border cells and their LCEs in live ovaries to determine how the cell cluster translocates. I will also construct Fluorescence Resonance Energy Transfer (FRET) constructs to monitor the activities of the PVR and EGFR receptors, as well as Rac activity. This will allow me to study the spatial activation of RTK signalli
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Recycling Environmentally Persistent Fluorocarbons with Metathesis and Shuttle Catalysis' (FluoroCycle) targeting Horizon 2020.

assistant: **Abstract**

Fluorine containing molecules and materials improve our quality of life. For example, fluorinated gases are used as refrigerants in the automotive sector, while fluorine containing polymers such as Teflon are common in households. Fluorine is also important for drug discovery and agrochemicals. For all its advantages, the fluorochemicals industry is unsustainable. Nearly all fluorine containing molecules on our planet are synthetic and single use. At the end of their lifetime they are either destroyed or end up contaminating the environment. Environmental contamination has been extremely damaging. Fluorinated molecules have contributed to ozone depletion (chlorofluorocarbons - CFCs), global warming (hydrofluorocarbons - HFCs) and water contamination (polyfluorinated alkyl substances - PFAS). If we are to continue to depend on fluorine containing molecules and materials, then we must find ways to reuse and recycle fluorine containing molecules at the end of their lifetime, we must stop our reliance on unsustainable natural sources of inorganic fluoride, and we must prevent unnecessary contamination of our planet with synthetic fluorine containing molecules.My objective is to develop new catalytic approaches for the recycling of fluorine containing molecules. My long-term vision is to establish new methods in which fluorine containing molecules such as HFOs, HFCs and PFAS can be used as a source of fluorine atoms and fluorine containing groups. I will pioneer new catalytic reactions that involve the exchange of fluorine atoms between two organic molecules and shuttle equivalents of HF and F2 from one organic fragment to another. These methods represent an important step forward to closed-loop recycling in the fluorochemicals industry. The new methods will be showcased in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'THE GENETIC BASIS OF MATING BEHAVIOR: PHEROMONE COMMUNICATION IN NOCTUID MOTHS'.

assistant: **Concept**

The genetic architecture of behavior is a major topic in biology, but remains poorly understood. The behaviors with the most dramatic effect on animal fitness are those involved in mate attraction and courtship, which are directly related to reproductive success. Males and females share a genome but have idiosyncratic roles in courtship rituals; mating traits thus experience sex-specific selection regimes. Variation at the gene expression level can facilitate sex-specific trait evolution to some degree. However, sex-specific traits inevitably covary, leading to correlated evolutionary responses (pleiotropy). Here I propose an innovative and multidisciplinary framework integrating a quantitative genetic approach to multivariate phenotypic evolution with functional genetic experiments. The key objective is to reveal how genes controlling traits involved in mating behavior can have widespread phenotypic effects across sexes by quantitative genetic measurements of pheromone communication variation in wild-type and knock-out lines of noctuid moths. I will examine the correlated evolution of pheromone signals in male and female moths and identify candidate genes using differential expression analyses. Then, I will examine the phenotypic effects using the cutting-edge CRISPR/Cas9 system and a quantitative genetic framework to test behavioral effects. The proposed research combines behavioral, quantitative genetic, and gene editing techniques and will make headway towards understanding the genotype-phenotype map of mating behavior. I will be based at the Institute for Biodiversity and Ecosystem Dynamics (IBED), an excellent interdisciplinary research institute focusing on functional biodiversity at the University of Amsterdam (UvA). Via training-through-research and a secondmen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Implications of the mesopelagic Remineralization for the OceaN Iron Cycle' to be submitted under Seventh Framework.

assistant: **Abstract**

The bioavailability of iron (Fe) has been shown to limit primary production in up to 50% of the ocean’s waters. As a result of its function in modulating Earth’s climate, the role of Fe supply on the oceanic carbon cycle has received widespread attention over the last two decades. However, much of the research to date has focused new sources Fe, and little attention has been directed toward controls on the supply of recycled Fe. Within the mesopelagic zone (the layer underlying the euphotic zone and extending to 1000 m), heterotrophic bacterial activity results in a dramatic decrease in the organic carbon exported from surface waters. For this depth range of importance for predictions of future changes in the ocean’s carbon cycle, bacterial remineralization and the fate of particulate iron (PFe) are, paradoxically, poorly understood. The proposed project seeks to better understand the functioning of the ocean’s Fe cycle through investigations of the bacterial remineralization of PFe within the mesopelagic zone.Using an innovative technical approach, the first part of the project will consist of the simultaneous and in situ measuring of bacterial remineralization rates and dissolved iron (DFe) release within the mesopelagic zone. Since the speciation of released DFe has major consequences on the bioavailability of upwelled fluxes of Fe, the second part of the project will consist of determining, using complementary in vitro experiments, the concurrent release of iron-binding ligands, as well as their size class (soluble or colloidal), during bacterial particle remineralization.This experimental work will be performed at different times of the year within two oceanic regions (the Southern Ocean and the Mediterranean Sea) that are characterized by contrasting Fe supply mec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Reusable launch vehicle for small payloads'.

assistant: **Objectives**

Approximately 600 satellites have been launched in the last 6 years with an average annual growth of 40%. The decline in launches has been seen since 2014. Over 100 small satellites were impacted by the 2016 delays, due to the fact that there are no rockets designed for small payloads and cubesats, and only 6 large launchers around the world accept small payloads. An alternative is the International Space Station (ISS), which requires special safety qualification for each payload and have limited flight opportunities. Therefore, concentration on relatively few launch vehicles increases uncertainty in the launch schedule for small satellite operators and limits near-term growth. The opportunity to test the technologies in suborbital space is significant for the developers of space, biomedical and pharmaceutical technologies, enabling them to advance the technology maturity or achieve space demonstration and qualification/certification, which otherwise will take more time or even will be impossible. PLD proposes revolutionary reusable rockets, to be used as micro-launchers and suborbital launch vehicles. The development of the micro-launcher foresees the demonstration of a smaller scale reusable rocket for commercial suborbital flights, ARION, whose design will be completed and then flight qualified within this Ph2 project. We will provide the first commercial micro-launcher service in Europe and second world-wide, exclusively designed for small payloads and fully managed by our team. For the first time ever, small payloads will fly to Space as primary payload and at an affordable price.  The key objectives of this project are to finalise the design of ARION suborbital vehicle, to develop a launch infrastructure, and to qualify the reusable launch vehicle in space, leadin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Ultrasensitive BIOsensing platform for multiplex CELLular protein PHEnotyping at single-cell level' (BIOCELLPHE).

assistant: **Innovation**

BIOCELLPHE provides frontier scientific and technological advancements to generate a breakthrough technology realizing the identification of proteins (i.e. phenotyping) as diagnostic biomarkers at single-cell level with unmatched sensitivity, multiplexing capabilities and portability. BIOCELLPHE proposes the generation of engineered bacteria able to recognize and bind to specific protein targets on the surface of circulating tumor cells (CTCs) responsible for cancer metastasis, thereby triggering the production of chemical signals that can be detected simultaneously, and with extremely high sensitivity by surface-enhanced Raman scattering (SERS). SERS is a powerful analytical technique that employs plasmonic nanoparticles as optical enhancers for ultrasensitive chemical analysis achieving single-molecule detection level. BIOCELLPHE will implement these advancements toward the generation of an optofluidic lab-on-a-chip SERS device enabling ultrasensitive identification and multiplex phenotyping of CTCs. We anticipate that BIOCELLPHE long-term vision and scientific breakthrough will lead to a sky limit technology that will be widely applicable, not only in the diagnostic arena, but also in many other applications (e.g. biomedical, environmental). No one has previously been able to attempt this vision due to current challenges and technical limitations, but we believe to be in a position to pave a way for achieving this now. To realize this highly ambitious project, BIOCELLPHE gathers a highly multidisciplinary community of leading experts in synthetic biology, nanotechnology, plasmonics, microfluidics, artificial intelligence, and cancer diagnosis. We believe that successful deployment of BIOCELLPHE has the potential to usher in a new era of medical diagnostics and it wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Digitisation: Economic and Social Impacts in Rural Areas' (DESIRA) targeting Horizon 2020.

assistant: **Abstract**

DESIRA will develop the concept of Socio-Cyber-Physical Systems to advance understanding of theimpact of digitisation in rural areas, linking analysis directly to the United Nation’s SustainableDevelopment Goals. Operationalising the Responsible Research and Innovation approach, DESIRAwill enrol agriculture, forestry and rural stakeholders in co-developing scenarios and policies in LivingLabs established in 20 European Regions, and a Rural Digitization Forum gathering 250 stakeholdersfrom all Europe. A Virtual Research Environment tailored to the purposes of the project will connect all participants and allow to increase substantially the interaction within the network.DESIRA will provide a Taxonomy and Inventory of Digital Game changers which will be implemented into an online Visualization Tool, a Set of Socio-Economic Impact Indicators aligned to the Sustainability Development Goals implemented into an online Socio-Economic Impact Tool, a Pan-European Assessment of digitization in European rural regions, a Needs, Expectations and Impact appraisal report, a Comparative Scenario Report based on scenario development activities of Living Labs and the Rural Digitization Forum, a Policy analysis and Roadmap, an Ethical Code to be adopted by researchers and innovators and recommended by policy bodies, five Use Cases that willreport a further analysis – co-created by Living Labs with the support of ICT specialists - of the most promising solutions identified by Living Labs, Showcase Technologies - including a Virtual Farm Platform -  that will create a selection of proof of concepts suggested by Use Cases. A detailed, multi-media dissemination, engagement and communication strategy will accompany the project from the beginning, looking at research as a multifunctional (resea
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Cities speeding up the integration of hydrogen buses in public fleets'.

assistant: **Concept**

Several European bus manufacturers consider the hybrid fuel cell (FCH) bus as the most promising technology to facilitate the decarbonisation of public transport. By leveraging the experiences of past fuel cell bus projects, implementing technical improvements that increase efficiency and reduce costs of FCH buses, as well as introducing a modular approach to hydrogen refuelling infrastructure build-up, the High V(Flanders).L(Liguria) O(ScOtland)-City project aims at significantly increasing the “velocity” of integrating these buses on a larger scale in European bus operations.•The project will address the following key issues: Increase energy efficiency of the buses and reduce cost of ownership:ohydrogen consumption down to 7–9 kg H2/100kmointegrating latest drive train and battery technologiesoavailability of 90% without the need of permanent supporto>12.000 hours warranty and decreased additional warranty costoincrease lifetime of key components as fuel cells and batteries.oinvestment cost <1,3 million euro•Reduce the cost of hydrogen supply:oLiguria: linking with renewable hydrogen sourcesoAntwerp: using by-product hydrogen from industryoAberdeen: making use of an existing hydrogen production and distribution mechanisms and eventually Scotland’s extensive wind energy resourcesoGroningen: by using H2 taken by a pipeline as a by-product from chlorine production•Consolidate past, current and future fuel cell bus demonstration activities by creating an active dissemination network of Hydrogen Bus Centres of Excellence in collaboration with the Hydrogen Bus Alliance, Global Hydrogen Bus Platform, CHIC Dissemination task force and JTI hydrogen bus demonstration projects. More specifically High V.LO City will:oBuilding on the experience of Van Hool the USA (21 buses 2005-2