RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'How Transposable Elements drive the Emergence of Phenotypic Innovations'.

assistant: **Concept**

How genome give rise to novel phenotypes is a major question in Biosciences. Transposable Elements (TEs) have co-evolved with host and are a major process by which organisms adapt to novel environments. Despite the discovery of the role of TEs in phenotypic innovations, the mechanisms and categories of TEs favoring their role in adaptive radiation remains elusive due to their repetitive nature. To palliate such lack of knowledge, I will take advantage of the new sequencing methodology providing chromosome length contigs, allowing to map precisely the different type of TEs, to sequence several cockroach species. Blattodea insect order is incredibly diverse and previous studies suggest the determinant role of TEs during Blattodea diversification, making it a perfect model to understand how and which TEs favor phenotypic innovations. I am particularly interested to investigate the role of TEs in the adaptation to wood feeding and sociality which led to the adaptive radiation of Blattodea species. My expertise in social evolution, its molecular basis and next-generation sequencing techniques, along with the computational expertise of Prof. Bornberg-Bauer lab will allow to detect the TE families responsible for the adaptation of specific phenotypes and as well by which mechanisms such phenotypes arise (e.g. chromosome rearrangement, gene duplication, regulation of gene expression). TEEPI will advance knowledge on the incredible role of TEs in the organismal adaptation to rapidly changing environments and may also provide a way to tame the expansion of cockroaches and termites, common pests that are on a rise with global warming. During TEEPI, I will gain scientific knowledge and transferable skills in computational biology such as genome assembly, and also on project managem
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Electrical signalling and growth control in zebrafish fin regeneration' under Horizon Europe.

assistant: **Concept**

The existence of endogenous electric fields in tissues is a fundamental feature for successful morphogenesis and repair processes, conserved across species. In a regeneration setting, wound electric currents can last hours to days, even after the wound is closed. Altering such currents by perturbing its underlying ion flows has been shown to affect organ growth via an increase in proliferative rates. Therefore, electric field directly takes part in regeneration. However, the relationship between ion flows, membrane potential, and cell proliferation for driving the regeneration response is not well understood.This project aims to uncover the dynamic electrical environmental changes that cells are exposed to upon organ damage, and how these can be coupled with biochemical signalling towards starting proliferation. By using the regenerating zebrafish larval fin as an experimental model, I will establish quantitative and interdisciplinary approaches that bridges injury sensing and regeneration dynamics across length and time scales. By establishing fast in vivo imaging and electrophysiology assays, I will measure the electrical signals in the fin tissue upon injury, providing an in-depth kinetic analysis of the electric spatiotemporal changes occurring within seconds of injury. In parallel, I will establish an analytic electrohydraulics model that connects cell-based ionic flows to tissue-scale electric field and currents, being continuously interwoven with experimental data and the idea of flexoelectricity. Then, I will generate and engineer optogenetic tools to spatiotemporally perturb ionic flows and electrochemical coupling strengths, directly testing the hypothesis of ion flow-derived electric currents as voltage-gated triggers for cell proliferation. This combined str
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Reaction Engineering of Heterogeneously Catalysed Polymerisation'.

assistant: **Objectives**

In order that European Industry be able to extract the maximum benefit from heterogeneously catalysed gas phase polymerisation, much fundamental scientific work must be done in process development, heat and mass transfer, development and morphology of the catalyst particles, how the catalysts, and the characterisation of the reactors and their hydrodynamics. The adaptation of the economically important family of metallocenes for use as heterogeneous (gas phase) catalysts needs significant work Heterogeneously catalysed polymerisation (e.g. for the production of polyolefins) is an economically important area of activity in Europe (approximately 7 billion ECUs in 1994), and is growing constantly as new catalysts (e.g. metallocenes) and new gas phase processes are developed to replace solution processes using organic solvents. Current problems faced in industry that limit the exploitation of new polymers and processes are:  reactor runaway due to heat and mass transfer problems, and reactor stability  Iack of direct on line sensors to monitor changes in the reactor and control product quality,  Iack of techniques for producing sticky polymers in gas phase reactors (esp. fluidised beds).  Iack of simulation tools for fluid dynamics and mixing in reactors (esp. multi phase systems),  a history of empirical reactor and process operation.  Iack of detailed knowledge/understanding of what takes place in the reactor. These problems will be resolved through the final results of this programme, which include:  Newer, cleaner, safer processes for the manufacture of new specialty polymers: creation of new markets, and manufacturing of elastomeric products such as PP, and Ultra low density PE, all in the gas phase.  Concrete model of the hydrodynamics of a fluidised bed polymerisatio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'European network for biological deuteration for neutron scattering and nmr' (DLAB).

assistant: **Innovation**

The D-LAB program aims to develop, produce and evaluate systems and protocols for the D/2H-labelling of biological macromolecules that will extend and enhance their structural and dynamical analysis at neutron scattering and NMR LSF throughout Europe. Specific objectives of D-LAB are to:- Exploit developments at the central Deuteration Laboratory in Grenoble to enable more efficient production of specifically H/D-labelled cells, proteins, nucleic acids and other bio-molecules;- Develop more efficient methods to produce deuterium labelled biological macromolecules that will benefit the European biological community;- Evaluate and exploit these methods and reagents in improvement of downstream technology, including data collection and interpretation for neutron scattering and NMR;- Train young scientists in these techniques. The tools and facilities produced will allow for higher throughput of experiments than are currently performed and will provide new, more sophisticated approaches to the solution of complex biological problems. The list of deliverables is considerable and includes new protocols and techniques for the production of H/D-labelled biological macromolecules and improved methods for analysis.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Monitoring functional traits by combining multi-scale and multi-temporal remote sensing data to assess biodiversity across Europe' (BioScal).

assistant: **Innovation**

Biodiversity is a critical indicator of ecosystem functioning and health.  Greater native biodiversity enhances ecosystem function, productivity, resilience, variability of the genetic pool, and a multitude of other ecosystem services. With the technology available now, remote sensing is the only efficient tool to assess biodiversity over regional to global scalesbecause it can provide measurements at appropriate spatial and temporal resolutions. Recent studies have started to explore the potential of remote sensing to estimate biodiversity attributes and patterns in natural and managed ecosystems. Most studies to date have used moderate resolution satellites to investigate species richness with somewhat mixed results. Few studies have had access to image spectroscopy data, which allows greater power in determining the relationships between spectral variability and biodiversity. While it is crucial to measure biodiversity across systems and scales, achieving this goal is challenging. Metrics or indicators are necessary for measuring and monitoring biodiversity at regional to globalscales. In this line accurate information on functional traits can provide a baseline for monitoring biodiversity. The main objective of this study will be to assess biodiversity based on functional trait monitoring on a diversity of forest communities along Europe. The proposed study will exploit the high spectral, spatial and temporal resolution data obtained from multiple remote sensing instruments. From a remote sensing point of view, the novelty or this research will be to take advantage of each sensor’s capabilities and extend our analysis in both space and time; and from an ecological point of view the novelty could be to develop a workflow for both downscaling and upscaling biodiversit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Tailor-Made Terpenoids: Exploring and Exploiting Natures Magic Methyl Effect' in the context of a Horizon Europe call.

assistant: **Objectives**

TAILOMET will explore and exploit the hidden magic methyl effect in nature to develop genetically programmable biocatalytic systems for the production of tailor-made terpenoids. Given the immense pharmaceutical and industrial importance of terpene natural products, methodologies for strategic structure modifications to fine-tune physicochemical properties are of vast interest. Introduction of a single methyl group can have dramatic impact on a drug lead’s potency, selectivity, or pharmacokinetics, and can alter olfactory reception of aroma compounds. The influence of methylations on the bioactivity of terpenes has, however, never been systematically investigated due to the limited availability of suitable methodologies to introduce such structural modifications into terpene scaffolds. Our recent discovery on a novel general pathway to homoterpenes, together with bioinformatic analyses indicates widespread interkingdom occurrence of terpene C-methylations in nature. The findings suggest a readily available and vast treasure trove for the discovery of novel enzymology to develop biocatalytic systems for selective methyl installation into terpene backbones. By exploration, exploitation, and re-design of these naturally available enzymes, TAILOMET will develop a comprehensive toolbox to close current knowledge gaps and unlock rapid access to terpenoids with fine-tuned or even novel properties. Besides synthetic advancements, comprehensive insights into the biological function of terpene methylations in nature might shed novel lights on intra- and interspecies communication with potentially valuable implications for chemical ecology and natural product discovery.


**Keywords:** Natural Products, Enzyme Discovery, Biosynthesis, Biocatalysis, Terpenes, Methyltransferases
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Who are we? Self-identity, Social Cognition, and Collective Intentionality' in the context of a Horizon 2020 call.

assistant: **Objectives**

What does it mean to feel, think, and act as part of a we? During the last few decades, the topic of collective intentionality or we-intentionality has been much debated. However, the following foundational issues continue to remain underexplored and unresolved: • How is the we related to the self? • What does the fact that one can adopt a we-perspective tell us about the fluid character of selfhood? • What type of social cognition is required in order to identify with and share a perspective with others?• What kinds of interpersonal relations are at play in different we-formations? • What is the relation between a transient we and a persisting we, and between a we that connects particular individuals who are known to each other, and a we that involves identification with a more anonymous and impersonal group?The working hypothesis of WE is that a systematic account of the we must be embedded in a more comprehensive investigation of selfhood and social cognition. This hypothesis draws inspiration from and will engage with seminal contributions by figures in classical phenomenology. The project will combine systematic theorizing with historical scholarship, and will challenge existing disciplinary boundaries by interweaving work on self-identity, social cognition, and collective intentionality. It will break new theoretical ground by developing a systematically convincing, phenomenologically valid, and empirically relevant account of the complex interrelation between the we, the you, and the I. In doing so, it will offer a clarification of foundational issues in the humanities and social sciences, and facilitate a much-needed cross fertilization between philosophy and theoretical considerations in the social sciences.Given the recent upsurge of ethno-nationalism and iden
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'EPISCOPAL NETWORKS AND FRAGMENTATION IN LATE ANTIQUE WESTERN EUROPE'.

assistant: **Innovation**

The fragmentation of the Roman World meant a reduction in scale, that is, a contraction in the system formed by economic, political, social and cultural relationship networks. Conversely, the Church survived into the middle ages as the only ‘supranational’ institution despite having faced some disruptive challenges. Political, symbolic and cultural relationships continued flowing along long-distance Episcopal networks in the fifth century. Nonetheless the nature and form of these long-distance networks was largely affected by the fragmentation of the Roman Empire.The aim of this project is to analyse how the fragmentation of the Roman world affected the evolution of the Episcopal networks and how these networks worked for or against the integration of the Western post-Roman World, both in cultural and institutional terms.This project will focus in three important Episcopal networks in Western Europe from the late fourth century to the late fifth century. These networks are the entourage around Ambrose, bishop of Milan (d. 396); the bishops from the monastery of Lerins (in the first half of the fifth century) and the entourage of Sidonius Apollinaris (d. 489). The research will include primarily Episcopal sources, Council Acts, Chronicles, and epigraphic sources, among others.The project’s conceptual basis and its main innovative aspect is the use of network theory and methodology as a tool for assessing the evolution in the scale, the form, the nature and the lasting patterns within these Episcopal networks.This research is not only expected to produce interesting results to current research on late antiquity and the early middle ages, but also to enrich historiographical approaches and knowledge transfer within the European Research Area.The product of this research wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Documenta Coranica Byzantina (DoCoByz). Byzantino-Islamica in the Age of Digital Humanities'.

assistant: **Concept**

To understand the evolving role of Islam in Europe, it is important to comprehend the forms and contents of intellectual exchange between the Latin and Byzantine world. Research to date has mainly focused on the Latin impact on the Christian perception of the Qur’an and Islam. Documenta Coranica Byzantina (DoCoByz) will address a significant research gap by diachronically exploring Greek translations of the Qur’an and anti-Islamic argumentation in Byzantine polemics (7th–13th century) before the first Latin translation appeared (12th century). This way it will be possible to synchronously compare their possible impact on the later Latin tradition.DoCoByz will trace the exact transmission lines of (I.) the Greek Qur’anic translation(s) (Testimonia Coranica Graeca), in order to (II.) document their reception and (re)use within Greek-Orthodox polemics (Episteme Islamica Orthodoxa), and to (III.) distill diachronically the common topoi and stereotypes of anti-Islamic argumentations as well as to synchronously study them with the pre-12th century Latin translations (Traditio Islamica Medievalis).The project is based on a genuine interdisciplinary approach: it combines Greek, Latin, and Arabic philologies with paleographical, historical, and theological work and methods of digital humanities. DoCoByz will create big data corpora giving open access to them as TEI XML files. It will process them into an online database which will contain a synoptical digital edition of all sources reaching out to both researchers and the broader public.After the project’s lifetime, the database can be continuously enriched with sources from (Early) Modern Times as the project's methodology especially focuses on reproducibility and interoperability with other projects. This will contribute to br
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Advanced Solar Cells and modules from Multicrystalline Silicon' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

The ASCEMUS project has been initiated by PV cell and system manufacturers (BP Solar, Eurosolare S.p.A and Shell Solar Energy) including the leading European research groups in the field of low cost solar cell processing (IMEC and University of Konstanz) and wafer manufacturer (Bayer AG). The main objective is to create the efficiency break-through of the industrial multicrystalline solar cells and modules produced in Europe. The project will start with the selection and testing of these laboratory solar cell processing steps which give the highest chances for a rapid improvement of the cost performance ratio. A compromise between the final cell efficiency and the capability for a low cost mass production will be emphasised. The ultimate goal is an integral, low cost, high efficiency solar cell process with well defined fabrication steps tested for implementation in the industrial environment. Apart from the solar cell process itself much attention will be paid to module fabrication since the process of integrating solar cells in a module, contributes with one third to the overall module cost. The expected technical achievements of the projects can be summarised: 1. Development of the wafering technique of larger area (up to 150 x 150 mm2) and thin (200 micrometers) multicrystalline silicon wafers. 2. Thorough testing and optimisation with respect towards implementation into mass production lines of the following, multicrystalline cell processing steps which are crucial for efficiency improvement - uniform texturization process: chemical, mechanical or plasma - high efficient emitter diffusion process: homogeneous and selective emitter - surface and bulk passivation by means of PECVD SiNx - fine line screen printing of contacts - light trapping 3. Combining the most eff