RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The electric VTOL-fixed wing drone for urgent medical delivery' to be submitted under Horizon 2020.

assistant: **Abstract**

The world is becoming more densely populated, which challenges our current healthcare system. The discernible acceleration of urbanisation will further decrease the average urban road transport speed with 30-50% in the next 3 years. Meanwhile many tasks like stock-keeping of blood and vaccines, and laboratory services are centralising for cost minimisation. Thereby increasing both the number of transports and transport distances of urgent medical supplies. The result is that road logistics operators are no future-proof solution to assure in-time delivery of urgent medical supplies.Avy has developed a medical delivery drone – the SkySaver - for urgent transport of clinical specimens, blood, pharmaceutical supplies, drugs and vaccines from and to hospitals, laboratories and production facilities. The SkySaver is a highly cost-efficient solution and can assure on-demand and in-time delivery of urgent supplies in populated areas over a distance of 150km. The SkySaver will deliver on average 30% faster than road courier, during rush hours the SkySaver is even 60% faster, while the transport costs are less than conventional urgent road transport. The SkySaver is the breakthrough solution disrupting the medical distribution industry enabling fast, cost-efficient and zero-emission delivery of urgent supplies. This will enable Europe to keep providing healthcare to people in need, and safe lives, every day.


**Keywords:** Urgent medical delivery drone system, smart on-demand logistics, healthcare supply chain, innovation, smart city logistics, transport test samples COVID-19
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Operational Planning Tool Interfacing Manufacturing Integrated Simulations with Empirical Data' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

OPTIMISED aims to develop novel methods and tools for deployment of highly optimised and reactive planning systems that incorporate extensive factory modelling and simulation based on empirical data captured using smart embedded sensors and pro-active human-machine interfaces. The impact of energy management on factory planning and optimisation will be specifically assessed and demonstrated to reduce energy waste and address peak demand so that operations that require or use less energy, can allow this excess energy to be re-routed to local communities. The OPTIMISED environment will use semantically enriched process modelling, big-data generation, capture and perform analytics to effectively support planning specialists, manufacturing engineers, team leaders and shopfloor operatives throughout the systems lifecycle. These next generation manufacturing systems  supported by data rich manufacturing execution systems with OPTIMISED technology will support a dramatic improvement in system performance, improved operational efficiency and equipment utilisation, real-time equipment and station performance monitoring, adaptation and resource optimisation.The OPTIMISED vision will be achieved by developing systems which are able to:1. Monitor system performance through an integrated sensor network, automatically detecting bottlenecks, faults and performance drop-off2. Continuously evolve to respond to disruptive events, supply chain disruptions and non-quality issues through factory simulation modelling3. Improve understanding and monitoring of energy demand curve and energy usage per industrial process and globally improve efficiency of production line through reduced energy waste4. Understand potential benefits, added value and impacts of participating in Demand Side Response
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Freshwater production from seawater and atmospheric moisture enabled by a solar-driven water generator' (SWaG).

assistant: **Concept**

The experienced researcher (ER), Dr. Siew-Leng LOO, will carry out a fellowship to develop a new cryogel-based material for onsite water production from seawater and atmospheric moisture. The fellowship will be carried out in Istituto Italiano di Tecnologia (IIT) under the supervision of Dr. Despina FRAGOULI. Specifically, the research aims to develop photothermal cryogels that can generate potable water via two approaches: (i) solar desalination achieved through solar-induced evaporation of seawater followed by condensation of the vapor generated, and (ii) atmospheric-water harvesting accomplished through the absorption of water vapor followed by (liquid) water recovery via solar-induced evaporation. This work will be the first demonstration of cryogels for solar-induced desalination and atmospheric-water harvesting. A portable device incorporating the photothermal cryogel that is easy to use will also be developed as a technological solution for decentralized water production in remote communities and disaster relief applications. Therefore, the work will not only advance the scientific understanding on desirable structures for enhanced performance in solar-induced desalination and atmospheric-water harvesting, but it also potentially have significant societal and humanitarian implications.


**Keywords:** Interfacial solar evaporation,  solar-induced desalination,  atmospheric-water harvesting,  point-of-use,  decentralised water technologies,  photothermal cryogels
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Mobile 3DTV Content Delivery Optimization over DVB-H System' (Mobile3DTV) targeting Seventh Framework.

assistant: **Abstract**

The MOBILE3DTV project aims at developing core elements of the next generation of mobile 3D television (3DTV). The project scenario assumes that stereoscopic video is captured and converted to a proper content format, then compressed, encapsulated, and broadcast to a large audience of mobile users, whose terminal devices receive, decode, and display the 3D content. Building upon two established technologies, namely the European DVB-H standard and auto-stereoscopic displays, the consortium will develop optimal mobile 3DTV data format and the associated content creation methods. Novel stereo video codecs, suitable for the robust delivery over the error-prone broadcasting channel, will be developed in the project. Resilience to transmission errors and concealment of degradations due to packet-loss, compression or stereoscopic artefacts will be investigated and optimized in terms of the quality perceived by user. Perceptual quality metrics will be developed in order to support the objective assessment of user satisfaction of the visualized 3DTV content. Advanced computational imagery algorithms for visual quality enhancement will be developed for both encoder and decoder side aiming to ensure the best possible visual experience for an acceptable computational effort. A prototype handheld device will be designed to receive, decode, and play stereoscopic video-streams.  It will be used as the terminal device of a complete end-to-end mobile 3DTV system to be setup within the project in order to demonstrate the feasibility of delivering mobile 3DTV content over a real DVB-H channel. The resulting mobile 3DTV technology will have the potential to become widely available to consumers for 3D-content delivery. This is expected to strengthen the leading role of Europe in introducing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'A novel microaerobic bioreactor to enhance Magnetotactic Bacteria growth and magnetosome production for application as biosorbents for metal recovery from electronic waste'.

assistant: **Innovation**

Annually, the world generates over 62 million tonnes of electronic waste (e-waste), which contains metals (e.g. lead, mercury, cadmium), which, if not properly managed, can leach into the environment, contaminating soil, water, and air. This situation poses a significant risk to human health and ecosystems, necessitating innovative recycling measures. So far, hydrometallurgical processes for metal recovery have made strides in addressing these issues. However, challenges such as their sustainability approaches, storage capacity, high energy costs, and scalability are problematic, leading to an urgent need for new solutions. The use of magnetotactic bacteria (MTB) represents an alternative low-carbon route for metal recovery, as they can uptake and store large amounts of metals in the form of magnetosomes, (magnetic nanoparticles that can be doped with a variety of metals for superior biotechnology applications) and biosorb a wide range of metals on the bacterial membrane. However, MTB are typically cultivated using off-the-shelf bioreactors as a one-fit-all system, with sparging hydrodynamics significantly limiting microbial growth as they require tightly controlled microaerobic conditions. Therefore, this interdisciplinary project aims to develop, optimize and scale up a sustainable biomanufacturing strategy (via enhancing production performance) for MTB growth using e-waste with a novel bioreactor design. This aim successfully addresses a significant environmental problem with a low-energy, sustainable process. Overall, the developed technology will create industrial potential for its utilisation in other applicable processes, such as the health sector. This project will have a great social and economic impact in Europe by contributing to reaching Net Zero and the Gre
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Disruptive GPCR Lead Discovery Platform Delivering New and Safer Therapeutics', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

InterAx Biotech, a Swiss company and spin-off from the ETH Zürich and the Paul Scherrer Institute has built PICARD, a unique drug discovery platform for the identification of drug candidates with improved efficacy and reduced side effects for the largest class of human receptors: The G-Protein Coupled Receptors (GPCRs). These receptors play a central role in many vital biological processes and they are implicated in a large variety of human diseases. Due to their complex nature and mechanisms that lead to the disease state, only 60 out of 375 pharmacologically relevant GPCRs have been successfully targeted by drugs, leaving >80% GPCRs without therapeutics. Bringing a drug to the market requires an investment of up to €2.2B; out of 5000 compounds only 5 will make it to the clinical trial phase and 9 out of 10 compounds fail during costly clinical trials. This inflates the price of the drugs that reach the patients, making the society paying for inefficiencies of pharmaceutical R&D. PICARD will enable better and earlier detection of safety and efficacy profiles of GPCR-targeting drugs by increasing quality and reducing costs and time-to-market of new therapeutics. The novelty of our discovery platform lies on the combination of our screening to find novel compounds, signalling Assays that cover the most common GPCR activation aspects and our Systems Biology approach leading to highly efficient and fast delivery of functional-selective compounds. We offer custom-designed PICARD services to pharmaceutical and biotech companies that are outsourcing key stages of their drug discovery process lowering risks and greatly reducing R&D costs. The revenue stream is generated both from fee per service and from long-term drug discovery partnerships with upfront and milestone payments
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Development and manufacturing of forest-based membranes for electrochemical energy devices'.

assistant: **Objectives**

Emerging technologies such as Proton Exchange Fuel Cells (PEMFCs) and Redox Flow Batteries (RFB) are expected to contribute to society’s transition towards renewable energy. However, these technologies use toxic, PFSA-based membranes which have caused serious ill effects on human health and the environment. In fact, the overall health cost due to PFAS usage is estimated to be between €52 and €84 billion per year, as a result of this the EU is placing restrictions to ban the substances, which initial bans already commencing. This has resulted in major companies such as 3M announcing to stop all production of PFAS-based materials by 2025, a decision worth 2 billion USD annually. To overcome this, Cellfion has developed a bio-based, ion-selective membrane derived from natural cellulose, the first of its kind. This innovation is 27 times more cost-effective compared to the competing solution while providing the potential for increased performance


**Keywords:** Membrane technology, ion-transportation, proton-transport ion-filtration, porous materials, dispersions, proton exchange membrane, fuel cells, redox flow batteries, cellulose, Nano particles, hydrogen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Hydrodynamics of Double Membrane Spreading in Biology' (HYDROBIOMEM).

assistant: **Concept**

Eukaryotic cells exist in highly dynamic environments and are subject to a variety of existential threats, ranging from viruses to pathological defects in their own genome. To cope with these challenges, cells have developed a conserved pathway in order to degrade harmful objects internal to the cell. This process is know as autophagy. Autophagy involves the formation of a double lipid membrane compartment that wraps around harmful targets, such as damaged organelles, protein aggregates or lipid droplets in order to facilitate their degradation. Although the genetic and molecular triggers for autophagy have been analysed in much detail, the biophysical principles governing such a dynamic process have received remarkably little attention. The biophysics of autophagy is highly complex biophysical process, involving the driven, non-equilibrium morphodynamics of a fluid membrane that must wrap its target. This incorporates molecular signalling and adhesion, vesicular trafficking and active force generation and complex flows of the lipid membrane in curved geometries as well as the Stokesian hydrodynamics of the embedding fluid. This makes the dynamics of autophagy essentially a problem of active soft matter physics.In HYDROBIOMEM I will build on demonstrable expertise in active soft matter physics, morphology and fluid dynamics to develop novel theoretical and computational models to give mechanistic understanding and predictions of the dynamics of double membrane wrapping in autophagy. I will apply these tools, in close collaboration with experimentalists, to test existing biological hypotheses and give new insight into this ubiquitous process in cell biology.


**Keywords:** Membrane Hydrodynamics,  Biological Soft Matter,   Wetting,  Low Reynolds Number Hydrodynamics
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'new machine tool for SimultaneOus pLate beVElling on all material types' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Founded in 1963 in Reggio Emilia (Italy), our company OMCA SRL (www.omcasrl.it) has grown to become one of Europe’s leading manufacturers of bevelling and chamfering machines (i.e. “cutting” angled edges), mainly used in construction, mining and shipbuilding industries. Our continuous investment in advanced technology and our commitment to quality and customer service has helped solidify our position as one of Europe’s leaders with approximately 10% market share and €2M in annual revenues. This project, known as SOLVE (simultaneous plate bevelling), provides an optimum quality and a significant throughput improvement that will decrease bevelling times by 50% compared with current market offerings. We have invested so far €175,000 in validating and testing our First Prototype (10kW engine power) in a controlled environment (TRL6). Our preliminary market research also indicates that the increase in productivity for our clients address a core need that will provide them with a clear operational advantage over their competitors. For our company, we expect Solve to further solidify our position as a leading player in the bevelling machine tool industry and provide us an estimated 60% increase in sales revenues, resulting in a total revenue of €3.2M by 2021.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Formation and Characterization of Protein Post-Translational Modifications and Assessment of Cellular Responses by Application of Metals in Biological Systems' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The chemistry of metals is rich and viewed in a biological context its diversity is crucial for a multitude of molecular functions in the living cell. Many of these reactions are very attractive to both academia and industry. In this proposal, I plan to develop novel applications of metal compounds to solve immediate challenges in mass spectrometry-based proteome research, but also will assess the potential risks of using nano-sized metals in our society. First, it is important to develop an efficient enzyme-independent method to synthesize large amounts of biologically relevant C-terminal amidated peptides. Presently, C-terminal peptide amidation poses a challenge in pharmaceutical production due to limitations of the two enzymes used for this purpose. The suggested approach in METALS will examine the specific binding of uranyl to artificially phosphorylated recombinant peptides. Data reveal that subsequent UV irradiation produces C-terminal amidated peptides. I will attempt to minimize the bias inherent in current phosphopeptide analysis, which comes from inefficient inhibition of phosphatases during cell lysis. Application of a recently developed gallium complex during cell lysis should limit the extent of this bias by binding phosphorylated proteins. The neutral conditions involved with the gallium complex reaction should also facilitate the possibility of enrichment of acid labile phospho-histidine peptides of which only a handful have been characterized. Finally, humans are now exposed to increasing amounts of artificially nano-metals applied via consumer products, food packages, and cosmetics. I will investigate this problem using advanced mass spectrometry, confocal microscopy, and biochemical assays of the response of human neural cells to nano-metal particles.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Springboard for excellence in advanced development of antibacterials'.

assistant: **Innovation**

The main goal of SPRINGBOARD project is to strengthen research potential of the Latvian Institute of Organic Synthesis (LIOS) through establishing long-lasting and sustainable collaboration network with the leading European research institutions – University of Antwerp, University of Copenhagen, University of Florence and University of Helsinki – in the area of advanced discovery and design of novel antibacterial drugs. An increased competence of LIOS staff (especially early stage researchers) on identification of new enzymatic targets, application of natural products and their synthetic analogues, biopharmaceuticals, antisense and peptide antibiotics as antibacterials, as well as experience on biofilm formation and quorum sensing molecules as targets for new antibacterial therapies will be achieved as a result.The implementation of SPRINGBOARD will ensure the establishment of platform of excellence in this area through:•exchange of the best practice via staff exchange and expert visits;•increase capacity building of early stage researchers;•improvement of research management and administration skills;•organization of joint events;•building capacity for participation in competitive joint proposals of projects for Horizon Europe and other relevant programmes;•dissemination, communication and outreach activities.This collaboration will ensure:•full exploitation of research and innovation capacity of LIOS;•rise of LIOS staff research profiles focusing on early stage researchers;•increase in LIOS visibility and integration in ERA;•contribution to actual socio-economic challenge in connection to widespread infectious diseases;•public awareness on the importance of development of new antibacterial drugs.SPRINGBOARD will contribute to the Responsible Research and Innovation ap