RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'European Forest Downstream Services- Improved Information on Forest Structure and Damages' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

It is the overall aim of EUFODOS to develop specific Forest Downstream Services (FDS) that are urgently required by regional European users in an economically viable manner and utilise the GMES Land Forest Core products as a basis for the development of these services. The specific FDS which will be examined and developed to a pre-operational level are related to assessment of forest damage and mapping forest functional parameters. As the GMES Land Core products are not yet operational the FDS will thus also provide a “pre-operational validation of the GMES services and products.”The FDS programme is based on 3 foundations: technical/methodological developments which will be based on an approach that combines Earth Observation (EO) and in-situ data as well as the GMES Forest Core products; the formation of a functional Service Network (SN) which includes effective representation/involvement of the user community, the service providers and the research community; and the assessment of the economic feasibility of developing the service cases such that they are sustainable. Thus these foundations form the following programme objectives:1.Development of a FDS Service Network comprised of service providers, users and the research community for effective involvement of all stakeholders and service delivery.2.The investigation and implementation of methodologies for forest degradation assessment and forest functions parameter mapping for the provision of pre-operational systems.3.The users commitments to participate in the validation of the Core products, as well as the utility assessment of the downstream services within their own work practices.4.The assessment of the economic cases for these different regional downstream services to ensure sustainability.All the objectives
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Catalyst Control over X-Fold Stereogenicity' in the context of a Horizon 2020 call.

assistant: **Objectives**

Catalytic, stereoselective methodologies to study the control over the configuration of stereogenic elements with three- four-, five- and six-fold stereoisomerism are proposed. Previous catalyst-stereocontrolled methods allowed the differentiation of a twofold number of stereoisomers for any given stereogenic element. It is thus anticipated that expanding the stereogenicity in stereoselective catalysis represents a significant advance for the field. The reunification of conformational analysis and stereoisomerism in organic synthesis is expected to provide an improved conceptual framework. Traditionally, stereogenic elements are considered to generate a doubled number of possible stereoisomers, which are assigned with standard stereochemical descriptors such as R and S. The overall number of possible stereoisomers in a molecule with a set of stereogenic elements (n) is thus commonly predicted as 2^n. This binary stereochemical understanding of stereoisomerism represents a current basis for organic synthesis and a wide range of bioactive compounds critical for our health care are skillfully prepared by controlling the configuration of desired stereoisomers. Control over stereogenic elements that generate more than a twofold number of possible stereoisomers thus dramatically extents the scope of current stereoselective catalysis and organic synthesis. 1: The underpinnings of conformational analysis and the catalyst-stereocontrolled synthesis will be conceptually unequivocally reunited. 2: The uncharted setting of catalyst control over three-, four-, five- and six-fold stereogenicity will be established by the development of versatile synthetic methodologies. 3: Novel molecular architectures featuring unique chemical topologies will be assessible, representing unexplored c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'A laser system for optimizing and cutting straight and curved wood pieces' (1994-1998) under Fourth Framework.

assistant: **Objectives**

The objective of the project is the development of a complete cutting line for hardwood cutting especialy adapted to small and medium european companies The process is located between log breakdown and secondary transformation and consists of sawing un-edged hardwood lumber (boules) into rectangular and complex shaped pieces with the highest value and recovery yield. It will take into account the complexity of the pattern (straight and curved pieces) and the raw material heterogeneity. The innovation will first concern the improvement and adaptation of a cutting laser system to saw solid hardwood, species such as beech or oak, up to 50 mm in thickness. The minimal cutting speed will be 5 m/min on 35 mm in thickness, with a depth of burnt surface limited to 0.3 mm, in one pass, in industrial conditions. The systeme will also be able to mark on the lumber sawing patern to be process with conventional saws. Because un-edged lumber is a very heterogene raw material (shape, defects, different quality zone), the second part of the innovation will be to develop a scanning station and an optimizer to improve the value and the recovery yield. They will have to be able to work on undefined raw and finish product shapes with different quality zones, a wide range of defect kinds. They also will take into account that with laser we are not any more limited to straight cutting from edge to edge. With conventional sawing, the average recovery yield is 50 %. Our objective is to increase the value yield from the same raw material by at least 25 % . The introduction of laser cutting coupled with a new optimization concept applied to solid wood processing is a very important step for the sawmill and furniture industry. To prove the results we will build a prototype working in industrial c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Training in vaccine development: combined glycoconjugate vaccine against meningococcus a,c, w135,y' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

The present training project will be aimed to develop glycoconjugate molecules against meningococcus group A, W135 and y and eventually to combine them with our anti meningococcus C conjugate vaccine to form a tetravalent anti- meningococcal vaccine effective in infants.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Symbiont-assisted cuticle biosynthesis as a key innovation contributing to the evolutionary success of beetles' (SYMBeetle).

assistant: **Concept**

To elucidate the key adaptations underlying evolutionary success remains one of the central challenges in evolution and ecology. However, rigorous experimental tests are usually hampered by the lack of replicate evolutionary events or the inability to manipulate a candidate trait of importance. SYMBeetle exploits the naturally replicated evolution of an experimentally tractable, symbiont-assisted key adaptation in beetles to understand its impact on niche expansion and diversification. Recent evidence indicates that beetles across at least seven different families associate with microbial symbionts that provision their host with tyrosine, an aromatic amino acid necessary for cuticle biosynthesis, hardening, and tanning. SYMBeetle addresses the hypothesis that the acquisition of tyrosine-supplementing microbes constituted a key innovation across phylogenetically distinct beetles that allowed them to expand into novel ecological niches, by relaxing the dependence on nitrogen-rich diets for successful formation of the rigid exoskeleton and protective front wings. Specifically, tyrosine supplementation may facilitate the transition to herbivory and allow for subsisting at very low ambient humidity, by facilitating the production of a thick cuticular barrier to desiccation. To test this, SYMBeetle will uniquely combine experimental manipulation of symbiotic associations to assess the symbionts’ contribution to cuticle biosynthesis and its fitness consequences (desiccation resistance and defense) with large-scale comparative approaches aimed at elucidating the taxonomic distribution, ecological contexts, and evolutionary origins of cuticle-supplementing symbioses. The results are expected to transform our understanding of microbes as important facilitators for the evolution o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Advanced manufacture of industrial bio-products by activated fermentation process (BIOFERM)' under Sixth Framework.

assistant: **Concept**

Specific biochemical reactions and their economical operations are the main advantages of bioreactors. They are widely applied in the industrial sector such as in the food and pharmaceutical industries, in bio technology and in municipal wastewater treatme nt plants. The biotechnological fermentation industry in Europe is faced with enormous legal restrictions such as the genetic law, embryonic protection law and so on. The fermentation industry lacks possibility for expansion due to the fact that new inst allations require new locations with the associated high investment costs There is a substantial need for compact and cost efficient biological fermentation system The intensive scientific efforts of the last 20 years in the genetic optimisation of the mi cro-organisms and in the classical bio-processes led to a drastically increase in the application of biotechnology in central Europe and to a substantial need for compact and cost effective biological fermentation systems The already existing experience w ith direct intake of ultrasound into smallscale bioreactors would be transferred into a by-pass ultrasound reactor technology. This new process omits the ultrasoundsystem installed in bio- reactor. This important step would lead to the possibility to use a lready existing bioreactors in the fermentation companies such as the food processing and biotechnology industries. With this type of reactor, a direct scale-up is quite possible Otherwise, the integration of the ultrasound in already existing fermentation reactors would lead to high investment and energy costs Ultrasound-systems will be coupled with biotechnology fermentation process to prove the already achieved results from Ultrasound-activated food processing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Priority environmental contaminants in seafood: safety assessment, impact and public perception' (ECSAFESEAFOOD).

assistant: **Concept**

Seafood has been recognized as a high quality, healthy and safe food item. Yet, some seafood can accumulate environmental contaminants with potential impact on human health. Limited information is available for those without maximum limits set by authorities for seafood, like priority contaminants, biotoxins from harmful algal blooms and marine litter. In order to increase seafood safety to consumers and reduce human health risks, ECsafeSEAFOOD aims to assess safety issues mainly related to non-regulated priority contaminants and evaluate their impact on public health.ECsafeSEAFOOD addresses these objectives with eight work packages (WPs) targeting priority environmental contaminants, including biotoxins from harmful algal blooms and marine litter. WP1 will elaborate a database with relevant information required for risk assessment gathered from literature and national monitoring programmes. WP2 will monitor contaminants in seafood using an ambitious sampling strategy following the recommendations of the Marine Strategy Framework Directive (Descriptor 9) and assess the effect of seafood processing/cooking on contaminants. In WP3, risk assessment (with data from WP1-2) and mitigation strategies will be implemented to reduce the impact of risky contaminants on human health. WP4 will develop fast screening/detection methods for relevant contaminants tailored to suit stakeholders needs to promote consumers’ confidence in seafood. WP5 will carry out the toxicological characterization of contaminated seafood in realistic conditions and will use alternative toxicological methods to provide tools for the risk assessment (WP3). WP6 will assess the links between the level of contaminants in the environment and that in seafood through controlled trials and case-study species, taki
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Network for the exchange and transfer of innovative knowledge between European wine-growing regions to increase the productivity and sustainability of the sector' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Building on a methodology for innovation-driven research previously developed and tested, the WINETWORK project has the ambition to stimulate collaborative innovation in the wine sector. The project will implement a methodology that has been successful in promoting demand-driven innovations in previous regional and European projects. This approach is mainly based on the interactions between a network of facilitator agents, several regional technical working groups and one European scientific working group. A participatory approach is used to translate results from science and practical knowledge into technical datasheets that are used to prepare materials adapted to end-users. A bottom-up approach is also used to identify a demand-driven innovation agenda. In the WINETWORK project, the approach will be implemented in ten regions from seven countries representing more than 90% of the EU wine production. The main topic addressed in the network concern the control and the fight against diseases that jeopardise the future production potential of the EU (Grapevine Trunk Diseases and Flavescence Dorée). As they represent a threat for the economic viability of the entire sector, these topics have been previously identified as a priority by winegrowers, scientists and decision-makers. As many winegrowers are testing innovative and sustainable approaches to fight these diseases, it is very beneficial to capture these ideas and to share them between EU countries. Innovative practices will be synthesized, tailored and translated to become fully accessible to innovation support services and to winegrowers. The project will then deliver a vast reservoir of existing scientific and practical knowledge related to sustainable vineyard management. It will also provide a methodology that
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Innovative training network: Immunoprofile-directed stratification of patients with the autoimmune disorder thrombotic thrombocytopenic purpura' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The PROFILE Innovative European Industrial Doctoral programme will develop improved tools for stratification of patients with the autoimmune disorder acquired thrombotic thrombocytopenic purpura (TTP). Patient stratification is needed in order to further develop personalized medicine approaches for human disorders. Therefore, a detailed understanding of the disease at the molecular level is needed. Furthermore, implementation of a robust set of novel biomarkers is essential for stratification of patients. Also, highly flexible platforms to rapidly develop novel therapeutics are crucial to further boost the field of personalized medicine. The research program is embedded in a unique translational training program, which emphasizes clinical needs as a driving force for development of novel, innovative diagnostics and therapeutics (for personalized medicine). There is intersectoral knowledge transfer between academia and companies at the European level as 6 different EU Member states are involved in the network either as beneficiary or partner organization. The PROFILE network will allow 6 early stage researchers to follow this unique translational training. They will be trained in the clinic to identify clinical needs, in academia where they will contribute to a scientifically ambitious project and in the non-academic sector where they will be trained in a novel technologies and commercializing bioassays endowing them with an unique PROFILE for further advancing personalized medicine in Europe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Programming Platform for Intelligent Collaborative Deployments over Heterogeneous Edge-IoT Environments' to be submitted under Horizon Europe.

assistant: **Abstract**

P2CODE envisions the design and development of an open platform for the deployment and dynamic management of end user applications, over distributed, heterogeneous and trusted IoT-Edge node infrastructures, with enhanced programmability features and tools at both the network infrastructure level and the service design and operational level. The platform is implemented following three innovative design approaches: i) The deployment and management of the applications is conducted by an orchestration framework that follows a vertical layered approach from the end user interface to the infrastructure management while spanning horizontally across the device-edge-core-cloud continuum. The deployment follows the user-defined networking and operational features of the application in its northbound interface and a tight integration with state-of-the-art IoT, edge/cloud computing, and networking platforms in its southbound interface through a well-define driver API framework. With this approach the full programmability and reconfigurability of resources across the continuum is enabled. ii) An open and extensible, programming toolset facilitates application development and deployment for large swarms of devices at the edge through a multi-role Internal Developer Platform (IDP) and new feature development and testing, iii) A secure and trusted framework for registering and authenticating IoT device and edge nodes entering the system as well as the data sharing and application deployment. The concept is tested and validated over a mature testing environment that integrates diverse IoT application areas in smart logistics, manufacturing, utility inspection, and community PPDR over a programable infrastructure extended to O-RAN, 5G, SDN enable core Cloud. The consortium addresses all
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Coordination of cell growth and cell division' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The dynamic properties of the cytoskeleton facilitate cell growth and cell division. The pattern and amount of cell growth, combined with the timing of cell division, generates the spectrum of cell sizes and shapes found in nature. Despite the fundamental importance of these processes, remarkably little is known about how cell growth and cell division are coordinated. In budding yeast, a core component of the cell cycle machinery, cyclin dependent kinase 1 (Cdk1), triggers polarization of the actin cytoskeleton and growth of a new cell early in the cell cycle. This places Cdk1 activity at the hub between the control of polarized cell growth and cell division. My work has demonstrated that signaling from Cdk1 activates highly conserved Rho family GTPases, including Cdc42, which both establish and maintain an axis of polarity along which cell division occurs. Cdk1 triggers the activation of Cdc42 via phosphorylation of a novel multi-protein complex that I have identified by mass spectrometry, comprising of multiple Cdc42 regulators. Exploring the mechanisms by which Cdc42 is activated by Cdk1 activity, and the targets that lie downstream of Cdc42, will therefore improve our understanding of how cell growth and cell division are coordinated, a key unresolved issue in cell biology.