RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Chemical and metallurgical aspects of arsenical bronze: the case of arsenic-loss in prehistoric  metal production' (ARSENICLOSS), addressing dissemination and exploitation.

assistant: **Impact**

The main goal of this project is to investigate out-of-equilibrium Cu-As alloys, i.e. 0-10 wt.% As in the range used in the transition period between Stone and Metal ages. The research protocol is made of several steps: equilibrium and out-of-equilibrium phase diagrams in the above mentioned range, evaluation of mechanical properties of Cu-As alloys in the most common metallurgical states (as-cast, annealed, cold-hardened, recrystallized), and estimation of the loss of As during metallurgical transformations (melting/casting, homogenisation and recrystallisation annealing) according to the number of iterations and of the treatment temperature and dwell time. The fulfilment of these objectives is of high importance for materials science applied to archaeology dealing with development and usage of this very first alloy produced by human kind.  The applicant will acquire and share with the scientific community new knowledge in the production, thermomechanical treatment and consequent properties of the misknown arsenical bronzes. She will use her metallurgical experience and archaeological knowledge (both matured in the field of tin-bronzes) applied to production, treatment and analyses of arsenical bronze. The additional knowledge the applicant will obtain within the project is related to the domain of phase diagrams creation and the usage of DTA, DSC and XRPD, under the supervision of experienced researchers from inorganic chemistry and metallurgy.  The project as a whole will provide for the first time: 1) out-of-equilibrium phase diagrams for the Cu-As system  2) determination of chemical, physical and mechanical properties of arsenical bronze in the range of 0-10 wt.% arsenic 3) a comprehensive overview on the actual loss of arsenic during metallurgical transformations
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'OPTIMAL LOW-NOISE ENERGY-EFFICIENT ELECTRICAL MACHINES AND DRIVES FOR AUTOMOTIVE APPLICATIONS', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Due to the replacement of engine-driven loads with electric power units, the electrical power requirements of a modern car has been rising rapidly during the last decades and are expected to continue to rise. As the power limitations of the storage systems and car alternators are rapidly being approached, different solutions have been searched for addressing this challenge. The research was oriented to the improvement of the electrical power units’ efficiency mainly through energy-efficient electrical actuators.As the electrification of vehicle propulsion continues to gain speed, the world of vehicle acoustics is also quickly adapting to the new needs of these vehicles. The sound and vibration signature of HEV/EV in general is quite different from vehicles powered by internal combustion engines. The current generation of HEV/EV poses a potentially different concern in that they are too quiet and therefore pose a threat to pedestrians when the vehicles are traveling at idle or low speeds.  On the other hand, missing the covering sound and the mechanical power of the ICE in several operating conditions of the vehicle, more and more electric powered units are getting relevant for the sound.The main objective of EMDA_LoOp is to enhance technological know-how and transfer of knowledge in the field of electrical machines and drives for automotive applications. Two experienced partners in this area are combining their efforts for the transfer of knowledge by collaborative research, two-way intersectoral secondments, sharing facilities, training and dissemination activities.  Co-operation and transfer of knowledge is dedicated to the development of energy efficient low-noise electrical machines and drives (EMDs) for automotive applications, through advanced multi-physics system
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Search for physics beyond the standard model with highly charged ions', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Spectroscopy has been a central tool in modern physics: it has helped us understand atomic structure, the expansion of the universe and the composition of exoplanet atmospheres. Today, high-precision spectroscopy is one of the most promising tools for investigating some of the most fundamental open questions: many theories beyond the standard model of particle physics can be tested by detecting tiny changes in atomic transition frequencies caused by the interaction with new particles, new forces or the variation of fundamental constants. An especially attractive target is the search for temporal or spatial variations of the fine-structure constant, which is predicted by several different theories. Highly-charged ions (HCIs) are especially well suited for this search, as they have transitions that are over an order of magnitude more sensitive to the fine structure constant than most other atomic systems. The precision necessary for these measurements will soon be within reach, thanks to recent demonstrations of sympathetic cooling and quantum-logic spectroscopy of HCIs.I propose an experiment that simultaneously probes two of the most sensitive transitions in HCIs using quantum logic spectroscopy and directly compares their transition frequencies. This method doubles the advantage of their enhanced sensitivities and reduces systematic effects introduced by an indirect comparison via the SI second standard. Together, these gains will allow an improvement of over two orders of magnitude on current bounds on the temporal variation of the fine-structure constant.I will also take advantage of the exotic nature of these extreme atoms to test further theories of fundamental physics. In particular, I plan to exploit their enhanced Rutherford scattering cross section to determine
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Vibrating carbon nanotubes for probing quantum systems at the mesoscale' (MesoPhone) under Horizon 2020.

assistant: **Objectives**

Many fascinating quantum behaviours occur on a scale that is intermediate between individual particles and large ensembles. It is on this mesoscopic scale that collective properties, including quantum decoherence, start to emerge.This project will use vibrating carbon nanotubes  like guitar strings just a micrometre long  as mechanical probes in this intermediate regime. Nanotubes are ideal to explore this region experimentally, because they can be isolated from thermal noise; they are deflected by tiny forces; and they are small enough that quantum jitter significantly affects their behaviour. To take advantage of these properties, I will integrate nanotube resonators into electromechanical circuits that allow sensitive measurements at very low temperature. First, I will study the motional decoherence of the nanotube itself, by using it as the test particle in a new kind of quantum interferometer. This experiment works by integrating the nanotube into a superconducting qubit, and will represent a test of quantum superposition on a larger mass scale than ever before. It will answer a longstanding question of physics: can a moving object, containing millions of particles, exist in a superposition of states?Second, I will use the nanotube device as a tool to study superfluid helium 3  the mysterious state of matter that may emulate the interacting quantum fields of the early universe. By measuring an immersed nanotube viscometer, I will be able to measure the behaviour of superfluid excitations on a scale where bulk superfluidity begins to break down.Third, I will add to the device a nanomagnet on nanotube springs, creating an ultra-sensitive magnetic force sensor. This offers a way to perform nuclear magnetic resonance on a chip, ultimately creating a microscopy tool tha
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'MicroRNAs and Cancer: From Bench to Bedside'.

assistant: **Concept**

Although studies addressing their role in cancer pathogenesis are at an early stage, it is apparent that specific microRNAs (miRs) and molecules involved in their biogenesis contribute to tumorigenesis. The ONCOMIRS consortium proposes a natural succession of four experimental strategies. Fist, we will DISCOVER and unveil novel miRs and components of their biogenesis machinery and investigate links between these molecules and human cancers. Secondly, we will CONNECT the information obtained on deregulated miRs with known cellular pathways involved in cancer, such as the p53 tumour suppressor pathway. This will be conducted using both forward experimentations, in which targets mRNA are experimentally identified for a number of miR aetiologically related to cancer, and reverse experimentations in which mouse models and cell lines with abrogated tumour suppressor pathways or activated oncogenes are used. To establish a causal relationship between dysregualted miRs and cancer development we will MODEL the tumorigenic processes in mice lacking or overexpressing particular miRs. Finally, since the specificity and potency of some miRs suggest that they might be promising as THERAPEUTIC agents, these models will be used in conjunction with other cancer models to explore miR-based therapeutic strategies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Statistical and Computational Genetics Tools for Investigation of Human History from Large Genetic Datasets' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

This proposal concerns the development of new statistical and computations methods for drawing inferences from genetic data. As a member of the Genographic Consortium, the author has access to both vast amounts of genetic data, and an array of scientific collaborators worldwide, seeking to answer questions regarding history of the human species, ancient migrations, etc. through analysis of genetic data. Some of the work already performed includes a method for mutation probability estimation from large datasets, and a paper on analysis of a large mtDNA database. A number of exciting challenges for the future work are discussed.  Once the author joins the faculty at Tel Aviv University, this research will contribute to ongoing international collaboration, to inter-disciplinary collaboration within the University and to increasing our understanding about the past --- and future --- of our species, and the manner in which people world wide are connected to each other as members of one extended family.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Implication of vitamin D and Wnt signaling crosstalk in epidermal keratinocyte stem cell fate. Role in skin morphogenesis and in epidermal tumorigenesis' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

The major goal of the proposed project is to study the role of vitamin D and Want signalling in skin morphogenesisand homeostasis, and in the alteration of these processes during the development of neoclassic and alopecia. For that purpose we will develop different experiments with keratinocytes and transgenic mice. First we will describe the interplay between vitamin D or some of its non-hypercalcemic analogues and Wntsignaling in different keratinocytes types, isolated from human and mice epidermis. One subpopulation of thesekeratinocytes is stem cells, which are able to regenerate all cell lineages present in the epidermis. We will express a modified vitamin D receptor (VOR), ÿ-catena or Left proteins (Want effectors) in these keratinocytes by retroviral infection. Then we will treat these cells with vitamin D or its analogues and analyse how their capacity to differentiate into the different keratinocyte lineages is modified. We will analyse how these genetically modified cells are able to regenerate an intermolecular epidermis (IFE), and which of them develop alterations during this process. We will study the changes in gene expression profiles promoted by those genetic modifications or by vitamin D treatment, using microarray analysis. In this way, we will be able to isolate new genes whose expression are regulated by every signalling pathway, and will define its implication in epidermal morph genesis invitro. The results obtained with these experiments will permit us to design the appropriate transgenic mice, expressing those proteins involved in vitamin D and Want signalling pathways, which are implicated in skin morphogenesis. We will use epidermal cell type specific keratin promoters to express those proteins into concrete keratinocytepopulations, including st
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Ultrasound guided cardiac arrythmia treatment' (USART), addressing dissemination and exploitation.

assistant: **Impact**

Every 30 second, a person in the Western world suffers sudden cardiac death and/or death from heart failure. These two conditions remain the major challenges in modern cardiology. However, new treatments now emerging offer hope in combating these events.Despite significant advances in new therapeutic approaches, current tools for risk stratification are insufficient, and treatment using ablation therapy or implantable pacemakers is often not optimized yielding less than satisfactory results.In order to bridge the gap between clinical needs and currently available technology for the assessment of cardiac dysfunction and its underlying etiology there is a need to develop competence in Europe within this area.Better tools for measuring and deriving cardiac deformation patterns, mechanical activation, electro-mechanical delay and accurate imaging guidance during electro-physiological ablation procedures have the potential to greatly improve the outcome for patients being treated for cardiac arrhythmias. The current key limiting factors to achieve this are:•Immature and unreliable tools for tracking cardiac mechanical deformation•Lack of tools for assessing electro-mechanical relationships in the heart•Lack of researchers capable of operating across the integrated fields of ultrasound acquisition, image processing, visualization, cardiac electro-physiology, cardiology and interventional cardiology.Through training and knowledge development in a focused research project, USART will provide Europe with experienced researchers with the cross-disciplinary understanding and research skills necessary to develop enabling technologies in an industrial setting. The longer term outcome of the project is new products which will benefit patients across Europe directly by advancing the s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Quantum Entanglement, Complexity, Quantum Computation' in the context of a Sixth Framework call.

assistant: **Objectives**

Entangled quantum systems behave in ways impossible in any classical world. Even as entanglement of simple composite systems is reasonably well understood, the nature of complex entangled systems is largely unexplored. We will investigate entanglement of increasing complexity, either by entangling more and more systems with each other, or by entangling systems with a larger number of degrees of freedom. Firstly, we plan to derive new Bell' s inequalities (tests of quantum non-locality) for higher-dimensional entangled systems and a larger number of choices for measurement settings for each system. The contradiction of quantum mechanical predictions with local realism is expected to be even stronger than currently known. Secondly, the entanglement that naturally exists between constituents of various complex physical systems such as chains of interacting spins will be studied. We will investigate how the amount of entanglement between several spins varies with the change of the number of spins, the strength of the coupling between them, temperature, the strength of the external field etc. The second part of the project investigates whether and how much entanglement is needed for quantum communication and quantum computation to outperform those which are based on the laws of classical physics. Firstly, we intend to develop new quantum communication complexity protocols exploiting higher-dimensional entanglement and to derive their complexity as a function of the amount of entanglement used. We expect to observe an increase of the separation between the complexity of the quantum solution and the best classical strategy as the dimensionality of the entangled systems grows. Secondly, by considering quantum computation as a communication process we plan to derive the complexi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Co-utilizing CO2 and metallurgical wastes for carbon-negative cement: science, technology, life-cycle impact assessment, end-of-life reuse, and process exploitation' (2021-2027).

assistant: **Concept**

Nearly 580 million tonnes per year (Mt/y) of ferrous metallurgical slags (FMS) are produced as by-products of iron, steel, and alloy production. The accelerated reaction of CO2 with Ca/Mg present in these FMS can result in the formation of Ca/Mg-carbonates, offering a relatively simple and low-energy pathway for CO2-abatement. This CO2-mineralization process has the capacity to directly sequestrate ~140 Mt-CO2/y globally, leading to the potential availability of ~720 Mt/y of carbonated-FMS as a by-product. The carbonated-FMS are expected to be rich in amorphous alumina-silica and Ca/Mg-carbonates: when used in combination with Ordinary Portland Cement (OPC), they are expected to form a composite cement similar to the presently marketed Limestone-pozzolana-OPC cement. In this context, this study focuses on the utilization of the carbonated-FMS to produce low-carbon cement with potential CO2-avoidance of ~500 Mt-CO2/y.To maximize the cementitious reactivity, the carbonation mechanism will be studied using different types of FMS and synthetic analogues of the major Ca/Mg-rich minerals present in them. The CO2-mineralization process and environment will be optimized to maximize the cementitious reactivity of carbonated-FMS by controlling their phase compositions, microstructures, and morphologies. When introduced as supplementary cementitious material (SCM), its hydration reaction with OPC will be studied to maximize itsutilization potential. For the final mortar/concrete products containing carbonated-FMS, the environmental leaching will be studied. Moreover, pathways for the end-of-life recycling of the product will be analyzed through cradle-to-cradle scenario analyses. Finally, for easy acceptance by the practitioners, the product will be subjected to detailed life-cycl