RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'A highly innovative and low-cost anti-counterfeiting solution which utilises micro-wires to maximise security and authentication' under Horizon 2020.

assistant: **Concept**

Counterfeiting of valuable and security documents is an increasingly serious problem worldwide. Banknotes, driving licenses, passport, ID cards, residence permits as well as event ticketing and stock certificates are all subject to increasingly frequent and accurate counterfeiting efforts. Each year, around €60B losses are experienced by governments as a result of counterfeiting. Current overt and covert anti-counterfeiting solutions are not effective at all as they are expensive to realize and can be easily overcome by skilled counterfeiters.To combat this, Wire Machine Technologies has developed SecWire, a ground-breaking anti-counterfeiting system which utilises ferro-magnetic micro-wires to offer high levels of IP security. The innovation behind the SecWire is in the manufacturing process which enables production of glass coated micro-wires of 2μm to 100μm diameter, small enough to be integrated in security paper. The SecWire is invisible and impossible to be removed, duplicated or deactivated. The micro-wires can be cut to any length and embedded (i.e. braided in the paper) into any products such as banknotes, passports, ID cards and event tickets. SecWire enables high security, it is durable and safe (microwires resist up to 600°C), it is 10 times cheaper than current solutions and it is highly scalable.During the feasibility assessment, a go-to-market strategy and the supply chain will be established as well as further IP protection will be pursued in other countries. Wire Machine Technologies will adapt SecWire for integration in different surfaces as paper, textile, plastic and polymers. They will also improve the production volume by increasing the number of working machines and expanding the production site. With the collaboration of secure document manufactu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on '3D Nanoscope: a highly accessible, high-performance device for live cell nanoscopy'.

assistant: **Concept**

Contemporary optical microscopy techniques are capable of imaging sub-wavelength (<400nm) structures. However, challenges such as phototoxicity, slow acquisition speeds, and difficulties in extending to 3D imaging have hindered their widespread adoption in live-cell studies. Light field microscopy (LFM) allows 3D imaging of biological samples with a single snapshot, reducing phototoxicity and allowing fast imaging of whole live cells. Recent breakthroughs have demonstrated single-molecule LFM with sub-100nm resolution, offering a straightforward optical design that holds immense promise for integrating complementary methods to study real-time dynamics in live cells without causing damage.3DNanoScope4All will develop and formalise a highly accessible, high-performance device for live cell nanoscopy. For that, three novel, yet robust, techniques will be merged in a single device: (i) LFM as the core technique, (ii) 3D-SRRF, facilitating high-resolution, rapid measurements and (iii) single-molecule orientation microscopy, providing spectroscopic insights into 3D molecular order. The combination of these cutting-edge technologies will enable both structural and dynamic measurements of live cells in a powerful yet affordable device.After validation, this nanoscope will be used to reveal previously poorly understood processes involved in the dynamics between viral particles (120nm) and cell membrane interactions during human immunodeficiency virus (HIV) infection. These advancements will not only broaden the current understanding of HIV infection but also pave the way for future research based on super-resolution microscopy techniques applied to other host-pathogen interactions.


**Keywords:** Super-Resolution Microscopy, Single-Molecule Polarization, Radial Fluctuations, Li
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Advanced materials solutions for next generation high efficiency concentrated solar power (CSP) tower systems', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

NEXTOWER shall introduce a set of innovative materials to boost the performance of atmospheric air-based concentrated solar power (CSP) systems to make them commercially viable. In particular, tower systems are appealing for the great environmental compatibility and offer tremendous potential for efficient (electrical and thermal) power generation. Yet, their industrial exploitation has been so far hindered by limitations in the materials used both for the central receiver - the core component - and for thermal storage. Such limitations dictate maximum working temperature and in-service overall durability (mainly driven by failure from thermal cycling and thermal shocks).  Improving the efficiency of a tower system entails necessarily improving the central receiver upstream and possibly re-engineering the whole systems downstream to work longer and at much higher temperature, especially in the thermal storage compartment. NEXTOWER will address this need by taking a comprehensive conceptual and manufacturing approach that will optimize bulk and joining materials for durability at the component level to achieve 25 years of maintenance-free continued service of the receiver and maximum thermodynamic efficiency at the system level. This is made possible through a unique combination of excellence in materials design and manufacturing, CSP full-scale testing facilities brought together in the Consortium, supporting the making of a full-size demo modules SOLEAD (tested in Spain and Italy) within the project. The successful achievement of a new generation of materials allowing for virtually maintenance free operations (limited to ceraminc parts) and increased working temperature shall result in the next-generation of air-coolant CSP highly competitive over other CSP alternative
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Process Analytical Technology Unit for Online Verification of the CIP Process in the Pharmaceutical Industry' (PATOV).

assistant: **Innovation**

A group of European SMEs with expertise in process cleaning and cleaning validation as well as other environmental technologies addresses a major market opportunity in the supply of a Process Analytical Technology (PAT) compliant unit for online verification of Clean-in-Place (CIP) processes used in the pharmaceutical industry. CIP equipments provide Water for Injection (WFI) along with cleaning agents at predetermined temperatures and pressures for cleaning production equipments in pharmaceutical or food processing industry. To conform to high level cleaning regulations, preconfigured, longer than necessary cleaning cycles are followed wasting tremendous quantities of water and cleaning agents. Additional laboratory testing of residual samples from the vessels determines whether further cleaning is required or the production process can resume. This results in long periods of process downtime, while the laboratory results are awaited. PATOV is a project designed to significantly optimise these CIP processes by introducing an online, realtime cleaning validation system that will ensure optimal cleaning, but simultaneously control cleaning time and cleaning agents used. This will enable reduction in cleaning costs and process downtime while at the same time providing more analytical information to the client. The critical challenges in the project relate to the continuous sampling and the separation of the liquid component from the returned WFI so that it can be fed into commercially available analysers. Superiorly, the selection and adaptation of a new analytical technology based on infrared spectroscopy seems to be promising. The project is expected to have a severe potential to improve the efficiency and competitiveness of pharmaceutical and food processing industry w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Structure and radiation processes of quasars from multifrequency monitoring' (1998-2002), addressing dissemination and exploitation.

assistant: **Impact**

Quasars are the most enigmatic objects in astrophysics. Although being subject of intense study for thirty years, many fundamental aspects are still poorly understood. During the last decade several discoveries opened new lines of research. Quasars dominated by non-thermal emission were found to emit large fractions of their radiation in the gamma-ray regime. Rapid variability implies very small diameters as well as highly efficient acceleration, radiation, and cooling mechanisms. Variations on long time-scales are related to morphological changes of jets on parsec scales. In at least one source, those long-term variations may be periodic. All of these results modified our understanding of the fundamental and phenomenological aspects of Quasar models in a significant way. Quantitative understanding suffers from the limited sensitivity of current gamma-ray instrumentation, from the insufficient sampling that can be obtained with any isolated facility, and from the complexity of the physical processes involved. We suggest to coordinate the efforts of the empirical studies by the leading European teams, making use of the unprecedented opportunities that will be available in Europe in the forthcoming years thanks to a unique set of new gamma-ray instruments and facilities (INTEGRAL, AGILE, HESS, and MAGIC). A complementary effort shall be undertaken by leading European theoretical teams to combine the state of the art models of MHD plasma jets, particle acceleration and radiation processes. It is also proposed to explore the high temporal frequency regime of parameter space and to study the rare and very fast events that may ultimately directly trace particle acceleration in AGN. The low duty cyle requires large collaborative efforts, novel statistical treatments of huge da
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Assessing and forward planning of the Geodetic And Geohazard Observing Systems for GMES applications' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Substantial improvement of our present knowledge of Earth System dynamics is paramount for the development of reliable strategies for actions vital to the human society in terms of achieving sustainable development and ensuring security. This requires fo r the various system components long-term integrated global data series from a large variety of sensors and networks combined with high performance rapid computing and a uniform and efficient access to distributed data archives and data information syste ms. The SSA proposed here aims (1) at assessing the status quo situation of two major components of the Earth observing system, namely the global geodetic and global geohazards observing systems as indispensable prerequisites for the consistent global m onitoring of the Earth system environment and security aspects of population and (2) identifying deficiencies and gaps in both components and providing advice for the implementation of necessary adaptations and potential new developments in network-, sha red computing-, and information/data management task for the observing techniques involved.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Domestic Devotions: The Place of Piety in the Renaissance Italian Home'.

assistant: **Concept**

Domestic Devotions brings together the study of books, buildings, objects, spaces, images and archives in order to understand how religion functioned in the Renaissance household. In opposition to the enduring stereotype of the Renaissance as a ‘secular age’, our research is premised on the view that religion played a key role in attending to the needs of the laity, and presents the period 1400-1600 as an age of spiritual revitalization. Devotions, from routine prayers to extraordinary religious experiences such as miracles or exorcisms, frequently took place within the home and were specifically shaped to meet the demands of domestic life – childbirth, marriage, infertility, sickness, accidents, poverty and death. This tight bond between the domestic and the devotional was neither institutionally nor legally defined. It cannot be adequately traced in any one type of source nor by means of a single approach. A rare combination of expertise and experience across several disciplines – social history, textual scholarship, and the study of art and architecture – is required to reveal the pivotal place of piety in the Renaissance home.The project moves beyond traditional research on the Renaissance in two further ways. Firstly, it breaks free from the golden triangle of Venice, Florence and Rome in order to investigate practices of piety in three significant zones: Naples and its environs; the Marche in central Italy; and the Venetian mainland. Secondly, it rejects the standard focus on Renaissance elites in order to develop our understanding of the artisanal household. Inspired in part by the rich historiography on the Protestant family, Domestic Devotions will shed new light on the roles of women and children in the Catholic home, and will be attentive to gender and age as
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'EUROpean Laboratories for Accelerator Based  Science' (EURO-LABS).

assistant: **Concept**

Nuclear and High Energy Physics explore at different scales what the universe is composed of and how it functions. Breakthroughs in accelerator and detector technologies combined with innovative experiments represent the key to new discoveries. High Energy Physics, while preparing for the HL-LHC, is pursuing the design of the next generation particle accelerators and detectors, balancing the present and the future. Newly available beams of nuclei far from stability and intense stable beams have opened new avenues, ranging from the production of new elements to the exploration of nuclear properties at extremes of temperature, angular momentum and isospin. It is of vital importance to simultaneously optimize the use of existing and new Research Infrastructures (RIs) to conduct curiosity-driven research addressing fundamental questions and technological challenges, and also advance projects with broad societal impact. This project provides efficient access to the available resources to a large fraction of EUROpean Laboratories for Accelerator Based Sciences (EURO-LABS). It allows the diverse community of users to choose the best state-of-the-art RI or a network of RIs to conduct high impact research, fostering knowledge sharing across scientific fields. The proposal brings together, for the first time, the three communities engaged in Nuclear Physics, Accelerator and Detector technology for High Energy Physics, pioneering a super community of sub-atomic researchers. It allows a synergic implementation of best practices for data management and activities relating to targeted service improvements at these RIs. Joint training activities are foreseen to develop the skills of the next generation researchers to optimally use the RIs services for scientific and technological disc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Co-ordinated project for local element def., impact of interoperability on system, frequencies allocation & protection, certifi. standardis., detailed service analysis & legal, institut.regulatory framework for GALILEO' in the context of a Fifth Framework call.

assistant: **Objectives**

The high level objective of the task is to contribute to the definition of the GALILEO Local Components by an analysis of the service providers needs:- Provide the Local Component elements of the GALILEO MRD/SRD for a generic set of applications and a Tender Dossier for the GALILEO Phase C/D.- Provide a Local Component development plan.- Provide a more detailed analysis of a number of Local Components, addressing the following specific aspects: The interface between the Local and Global Components of GALILEO and other communication, reporting and navigation systems.The performance of, and the additional signals required by, the Local Component and the spectrum requirements. The commercial or public service feasibility of the Local Component opportunity taking note of the potential for revenue for the GOC. To include a cost assessment and cost implications upon the Global or Regional Components. Legal or regulatory issues that may affect the Local Component public/private exploitation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Historical Patterns of Development and Underdevelopment: Origins and Persistence of the Great Divergence' (HI-POD).

assistant: **Concept**

Understanding the ‘great’ and ‘little’ divergences between Northwest Europe and the rest of Europe, and between Europe and the rest of the world, implies considerable challenges, both in terms of quantification and analysis. In terms of quantification, the major European challenges are to be found in the pre-1800 period, although much work remains to be done in quantifying post-1800 performance elsewhere. This proposed research project fits very tightly with the objectives of this call. We will be explicitly exploring the “relations between world regions and the factors shaping different development paths in a historical perspective” (Area 8.4.1). We will be explicitly focussing on the experiences of Asia, Africa and Latin America, and will be drawing not only upon European-based scholars but on a Latin American partner to this end (Activity 8.4). In terms of the specific topic addressed, “SSH-2007-4.1.2”, the proposal focuses explicitly on the way in which “development processes have and are being affected by relations between world regions and countries”, and on the links between uneven development and such relationships. The project will indeed look at whether and how uneven development is linked to such relations, both past and present; at “the extent to which historical relationships such as colonial and post-colonial relations affect today’s development paths”; at “the role of urbanisation”; and at “gender and development relations”, to which we will be devoting an entire work package.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Moving cell-based immunotherapies to  fight bacterial lung infections into the clinics' (2021-2027).

assistant: **Concept**

Harnessing the immune system to combat global diseases has introduced a new era in modern medicine. The iMAClung proposal will extend this concept and will pave the way for the first immune cell-based therapy to combat bacterial airway infections. With more than 2 million deaths around the world in 2020, lower respiratory tract infections are still the deadliest communicable disease with unmet medical need, highlighting the necessity for radical new approaches to develop therapeutic avenues. The iMAClung proposal aims at the adoptive transfer of human macrophages directly into the infected lung and to restore the endogenous alveolar macrophage (AM) cell pool to efficiently resolve bacterial airway infections and to mediate lung regeneration at the same time. iMAClung will harness the unique features of induced pluripotent stem cells (iPSC) to use macrophages (iMonoMac) as a cell-based immunotherapy following the adoptive transfer of these cells directly to the side of pulmonary infection. iMAClung is built upon the pioneering work of the ERC-Stg “iPSC2Therapy”, in which the anti-bacterial activity of iMonoMac against a variety of pulmonary (myco)bacterial infections has been successfully demonstrated in vivo. In addition, “iPSC2Therapy” has also successful shown the first scalable production of “off-the-shelf” iMonoMac using industry compatible bioreactors, which now paves the way for the development of seminal (non)therapeutic concepts. To enable clinical transfer, iMAClung will build a team of medical, scientific and industrial experts, all dedicated to bring iMonoMac into humans. To enter the next stage of the clinical translation pipeline, a path towards the clinics will be developed, which will facilitate subsequent exploitation and transfer into patients. iMAClung