RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'THE POLYPLOIDY PARADIGM AND ITS ROLE IN PLANT BREEDING' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Polyploidization is a major force in the evolution of both wild and cultivated plants. The remarkable superiority of polyploids has been noticed plant breeders, who have used this trait in different approaches in order to obtain increasingly improved plant cultivars.  Moreover, polyploidization is likely to be one of the most important mechanisms of sympatric speciation. All seed plants have experienced at least one round of whole genome duplication in their evolutionary history. The formation of polyploid plants within diploid populations tends to be isolated events. And even when a polyploid individual is formed, to reproduce it will cross with diploids, and this match is unsuccessful for the existence of the “triploid block”, a critical biological barrier in the production of viable seeds. Many species are sensitive to triploid seed production, but not all. Little is known about how polyploid plants were formed in nature and the way that triploid block has emerged in plants. Therefore, understanding of the genetic network controlling the triploid block will be fundamental since this is a preliminary step in the generation of polyploids. Here we propose: i) to study natural and recently synthesized polyploid series of several species that have been extensively characterized in the past few decades from the physiological, reproductive and ecological aspects; ii) to fill the gaps in the information on non-model species regarding: chromosomal changes, gene loss, gene expression, methylation and physiological changes and ecological features and iii) to understand the genetic network controlling the triploid block viability. The overall goal of the proposal is to allow for a synergy of inter-related European and international expertise to better understand the mechanisms o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Janus Nanoparticles as Novel Ferroelectric Materials' (2007-2013).

assistant: **Innovation**

The goal of this proposal is the generation of new ferroelectric materials based on bifunctional monolayer-protected metal nanoparticles (MPMNs) and supracrystals based on these anisotropic MPMNs. These Janus nanoparticles, named such for their characteristic pair of hemispherical faces, are expected to exhibit novel ferroelectric properties due to their inherent non-centrosymmetry and resulting permanent dipole. In addition, these MPMNs are expected to exhibit superparaelectric properties. This research will create the first such materials using several combinations of ligands in the protecting monolayer, such as alkanethiols and fluorinated alkanethiols. The work will begin with a systematic study, allowing optimization of synthetic parameters for forming Janus MPMNs. The ferroelectric properties of these Janus nanoparticles will be unlike any observed for MPMNs previously, due to their ubiquitous centrosymmetry and corresponding lack of a permanent dipole. Furthermore, the properties observed will be novel with respect to existing ferroelectrics due to its composition of nonferroelectric metals and organic ligands. Components with inherent ferroelectric properties, such as BaTiO3 and vinylidene fluoride, will then be integrated into the anisotropic materials. The integration of natively ferroelectric components into a system with emergent ferroelectric properties is expected to produce entirely novel multiferroic materials. The assembly of Janus MPMNs into supracrystals will also be explored in detail. The assembled supracrystals are expected to exhibit non-centrosymmetry, yielding a second class of novel ferroelectric and piezoelectric materials Ferroelectric materials can also be integrated into these supracrystals, yielding products with more complex and tunable p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Economy of Non-Elite Mycenaeans' (EcoNoMy).

assistant: **Innovation**

What is it like to live like common people in a Kingdom? The archaeology of Greece in the Late Bronze Age is dominated by the glory of the Mycenaean palaces and the rich warrior burials. The role of the non-elites remains at large an enigma, although recent research suggests that their contribution to the economy was much more critical than previously thought.  EcoNoMy will apply a novel combination of bulk and single compound carbon and nitrogen amino acid isotope analyses from bone collagen, methionine sulphur isotopes, food and environmental debris from calculus, and proteins adsorbed to pottery, in order to shift the attention from elite burials to non-elite lifeways and construct an alternative narrative of the political economy. With this unrivalled integration of markers of subsistence, EcoNoMy will create a dynamic discussion on regional political ecologies and political economies and overcome the current stall in research, created by previous methodological limitations that offer a unidirectional -palatial- view of society. With a regional focus on Western Greece, where current excavations suggest the presence of a complex system of exchange with the Adriatic and the Balkans, EcoNoMy will be the first:1. to offer this high-tech combination of methods to reconstruct for the first time the economic character of diverse, non-elite regions 2. to directly compare and contrast dietary evidence between individuals and their pots 3. to establish the applicability of this combined methodology in archaeology but also the relative merit of each method in relation to preservation and site particularitiesThe outcome will place the applicant at the forefront of isotope researchers and ground truth an integrated analysis, which can be applied to all archaeological populations
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Stimulation of SME START-ups in life science technology' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

* Formulation of regional innovation strategy following the value chain of companies (life sciences cluster approach);* Setting up of an intermediary foundation or company for acquiring international funding and the establishment of networks;* the role of a regional science park as incubator;* marketing of scientific results by a university workshop or a similar intermediary;* involvement of clinicians (direct users) in start-ups;* guardianship of new companies by well established companies;* creation of a seed fund" which extends the possibilities of common venture capital schemes* continuous education and training* the "twinning concept" where a (potential) start-up is twinned to an (international) partner with complementary but synergetic business activities.Specific results expected at the end of the project:* a generic, region-based, model describing the required infrastructure/support for start-ups based on the various innovation mechanisms validated.A set of measures which optimally influence the cultural setting in a university/research.* Organization thus motivating scientists to market and exploit their knowledge.* An action scheme for regional bodies to assist in SME start-ups.* An integrated approach to knowledge transfer and vocational training.* A strategy for (international) partner selection.* Transfer of experience and models to the European innovation scene"
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Promotion of Eu biomass technology in agro-industry of high-potential third countries' to be submitted under Fifth Framework.

assistant: **Abstract**

The main objective of the proposal is the promotion of EU Agro-Industry residues combustion technologies, developed by European SME manufacturers, in China, Turkey and Uzbekistan. Few EU SME boiler manufacturers have developed specific technologies to overcome operational problems due to the high concentration of inert and ash in the feedstock, which causes serious maintenance problems and long downtime periods. There are state of the art systems that matched in the EU, however, the main markets are those outside the EU in countries with very large production of cotton, rice and wheat. The aim of this project is to assist these EU SME companies to penetrate the international market and to maintain their leading position. This will be achieved by preparing organised participation in international business exhibitions and use of co-ordination promotional actions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Reconnecting transmission to global tuberculosis control by mapping pathogen transmission events to host infection status'.

assistant: **Objectives**

The annual decline in tuberculosis (TB) incidence is not greatly different from that of the ‘90s, when no coordinated efforts in global tuberculosis control were in place. The failure of current TB control programmes to accelerate TB elimination has multiple causes, including losses of TB cases at the different steps of the TB care cascade, and a chronic lack of funding hampering innovation. Additionally, we have failed to halt transmission in many settings, as we have failed to incorporate our improved understanding of transmission in TB control programmes. Our current approach to controlling TB is focused on a narrow view of who is transmitting the disease (symptomatically active TB cases), while there is a growing consensus that the traditional latent/active dichotomy is no longer valid, and that asymptomatic individuals with active TB signatures are also likely to be transmitting the disease. There is a critical lack of high-resolution data from different settings on the contribution to the transmission burden of cases with different infection statuses. To fill this evidence gap, I propose synergizing three recent TB research developments; We can now use host blood transcriptomics to discriminate between infection status within the latent pool of individuals. We can now quantify transmission at a resolution not previously available, using pathogen genome sequencing. We can now use phylogenetic and epidemiological models to identify when transmission has happened. Combining these three key developments with TB cohorts from multiple settings, and available tools from bacterial population genetics, high-throughput functional genomics and infection biology, we will be in a key position to answer these burning questions about the nature of TB transmission and the host an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Disruptive polyurethane foams with improved passive fire protection to increase energy efficiency & safety in buildings, houses and transport.' in the context of a Horizon 2020 call.

assistant: **Objectives**

Nearly Zero Energy Buildings are nowadays the focus of construction companies since EU Directives aim to reduce the Carbon emissions to atmosphere. Buildings are responsible of 28% of all CO2 emissions with space heating accounting 65% of all energy consumed. The need for reducing heat leaking through a better insulation of constructions is a key strategy to reduce the CO2 emissions responsible of the Climate Change. On the other hand, the rationalization on the consumption fossil resources through the use of renewable and biobased raw materials is of a strong interest for customers and end-users in construction market. In addition to the thermal performance and sustainability, insulating materials must demonstrate a safe use, especially when a fire takes place.Polyurethane foams (PUR) are the most efficient insulating materials used in construction. However, the main critical problem for them to become the preferred insulation material is a dangerous behavior when exposed to flames due to their high flammability and fast fire propagation, as well as the high amount of extremely toxic fumes released by PUR materials hen burning.To address these challenges, INDRESMAT has developed SAFE-PUR, a new top class of biobased PUR insulating foams that solve the main critical problems related with the lack of passive fire safety of conventional PUR foams. SAFE-PUR foams offer the following results: 1) improve the Thermal Insulation in buildings 15-20 %, 2) increase the Passive Fire Protection 70-80% and 3) reduce the C-footprint 60-70% of insulation materials compared to conventional of PUR foams. Our target is to reach a 12% of our Serviceable Operative Market partnering with a top chemical manufacturer of PUR formulations interested in SAFE-PUR foams to achieve a large-scale ma
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Equidistribution, fractal measures and arithmetic' (EFMA) under Horizon 2020.

assistant: **Objectives**

The subject of this proposal lies at the crossroads of analysis, additive combinatorics, number theory and fractal geometry exploring equidistribution phenomena for random walks on groups and group actions and regularity properties of self-similar, self-affine and Furstenberg boundary measures and other kinds of stationary measures. Many of the problems I will study in this project are deeply linked with problems in number theory, such as bounds for the separation between algebraic numbers, Lehmer's conjecture and irreducibility of polynomials.The central aim of the project is to gain insight into and eventually resolve problems in several main directions including the following. I will address the main challenges that remain in our understanding of the spectral gap of averaging operators on finite groups and Lie groups and I will study the applications of such estimates. I will build on the dramatic recent progress on a problem of Erdos from 1939 regarding Bernoulli convolutions. I will also investigate other families of fractal measures. I will examine the arithmetic properties (such as irreducibility and their Galois groups) of generic polynomials with bounded coefficients and in other related families of polynomials.While these lines of research may seem unrelated, both the problems and the methods I propose to study them are deeply connected.


**Keywords:** spectral gap, random walks on groups, local limit theorem, Bernoulli convolution, self-similar measure, Furstenberg boundary measure, generic polynomial, irreducibility of polynomials
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Development of super vacuum insulating panels and product integration services'.

assistant: **Innovation**

Global warming, ecological pollution and health issues drive the EU to seek for efficient reduction of energy consumption by thermal insulation. The proposed project suggests a new concept for thermal insulation of refrigerators, transportation boxes, cold storage rooms, buildings etc. The idea is to keep the insulating panels in vacuum inside sealed laminated bags (Vacuum Insulating Panels - VIPs).The project work programme has two dimensions:1. Improving VIP performance, including development of VIP barrier film, permeation test methods and VIP performance testing;2. Service to efficiently integrate VIPs into end product, including modelling an optimisation of VIP performance under the different in-use conditions; flexible designing tools for efficient integration; performance test methods for VIPs and for integration of VIPs into end product, end-of-life program (recycling).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Deep-sea fish vision pushing limits of the vertebrate eye'.

assistant: **Objectives**

Deep-sea fishes are known for extraordinary adaptations including enhanced sensory systems. They have eyes often modified in shape, anatomy or at the molecular level. Fascinatingly, some deep-sea fishes have evolved unique vision to potentially see colours. Here I propose to study functional evolution of this visual system, and to target the crucial question – can deep-sea fish see in colours? To perceive light, vertebrate retina has two types of photoreceptor cells, the rods for dim-light vision and cones for daylight colour vision. Many deep-sea fish lack cones, which makes them colour blind. The novel visual system based purely on multiple different rod opsins possibly overcomes this limit, and it is not found in any other vertebrate. In SensingDEEP I aim to “zoom” into the level of single rod/cone cells to understand deep-sea molecular adaptations of vision. I will target species with 1) the novel multiple-rhodopsin visual system and test if it has a potential to serve for colour discrimination. With multiple rhodopsins expressed in the retina, single-cell transcriptomics will either reveal rod cells sensitive to different colours, or alternatively, “superpowerful” rods sensing along the entire light spectrum. Both options would be unique among vertebrates. Further I aim to focus on the deep-sea species with 2) challenged rod and cone cell identity with mismatch of molecular machinery of both (rod and cone) types. Lastly, I will also test 3) how rare these extreme adaptations are in deep-sea fish diversity using the high-quality whole-genome sequencing. In the species with multiple rhodopsins, I will specifically focus on their genomic architecture and gene regulation by applying single-cell multiomics. SensingDEEP combines modern genomic tools with rare and unique
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Engineering vascularized tissue constructs from human embryonic stem cells' (VASCTISS) under Sixth Framework.

assistant: **Objectives**

The current status of rapidly increasing demand for organ and tissue transplantation in Europe and world wide has promoted tissue engineering as a promising alternative, in particular the use of stem cells. Human embryonic stem cells (hESC) have the advantage of differentiating to all cell types in the body and high proliferation capabilities. Considering their ability to organize into complex multi-cell type structures during embryonic-like differentiation, hESC can potentially provide a source of cells for tissue engineering applications and meet the growing demand for viable human tissue structures in therapeutic clinical application. The aim of this proposed program is to develop a new approach for the use of human embryonic stem cells (hESC) in engineering tissue substitutes, using three-dimensional cultures on biodegradable polymeric scaffolds.Our experimental strategy will comprise of:i) Three-dimensional culture of differentiating hESC on polymer scaffolds and in vitro tissue vascularization.ii) Engineering complex vascularized tissue substitutes and their implantation in immune deficient animals to study integration and vascularization in vivo.We intend to focus on three-dimensional multi cell-type interactions and organization, and to study the key factors in the vascularization process. Full comprehension and control of hESC differentiation and 3D organization could pave the way to develop new tools for engineering human tissues from hESC for tissue repair and various transplantations. This can also provide unique culture systems for studying human embryonic cellular interactions.