RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Data Privacy in Digital Markets'.

assistant: **Innovation**

Focusing on verifiability, PRIVDIMA studies the regulation of data privacy to protect consumers from excessive price discrimination in digital markets.PRIVDIMA breaks with previous literature by acknowledging that data has a verifiability effect. It proposes a study of data privacy regulation by explicitly modelling this verifiability effect. Its motivation is as follows: 1) data collection in digital markets renders private information verifiable; 2) due to unravelling, this verifiability effect of data impacts regulation at a fundamental level; 3) extant work on privacy regulation abstracts from the effect; 4) data privacy rules that ignore verifiability effects lead to misguided regulation. PRIVDIMA is to rectify this.PRIVDIMA has 3 objectives. Objective 1 is to incorporate verifiability in the state-of-the-art theories of mechanism and information design, readying them for the analysis of a new range of problems where verifiability matters. Objective 2 is to derive concrete policy implications for data privacy based on regulating the use of data to limit price discrimination. It yields new insights on regulating both long and short run contracts in models of behaviour-based price discrimination. Objective 3 is to derive concrete policy implications for data privacy based on regulating the collection of data. It yields insights on how to prevent an unravelling of private information by which the verifiability effect of data hurts consumers. Objective 1 implies a major advancement for the field of economic theory. Objectives 2 and 3 ensure that consumers obtain a fair share of the benefits from digitalization, promoting not only equity and fairness, but also public support for future digitalization, allowing societies to reap its benefits while avoiding social conflic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Embodied Cognitive Models for Fluent Human-Robot Interaction'.

assistant: **Concept**

Robotics is moving from industrial applications into personal and office environments, in part due to converging trends of an aging population, a shrinking workforce, and a decrease in production costs. The research field of Human-Robot Interaction (HRI) studies the models and algorithms necessary for robots to interact with non-professional humans in these new environments.However, most HRI models are structured in a discrete turn-taking framework, based on dialog, planning, and state-action models. This usually results in a rigid and delayed stop-and-go interaction, which is unlike the simultaneous, fluent action coordination humans are used to from each other.This research proposes to bridge this gap by evaluating new computational models enabling fluent coordination in human-robot interaction. The goal is to design robots that interact with untrained humans in a more natural and human-acceptable way, facilitating their integration into homes, offices, hospitals, and workshops.The research proposed is based on recent cognitive and neurological research in embodied cognition, which sheds new light on the how humans coordinate their actions in a fluent manner. It proposes to computationally model these findings - in particular those of perceptual emulators and real-time action predictors -  and to implement them in a human-robot collaborative setting. It also proposes to conduct human-subject studies evaluating the benefits of these new models, and their acceptance by untrained users.The project's potential is to suggest new research paths in HRI, extend the current knowledge in embodied cognition, and produce practical outcomes for the design of robotic systems for the general population. Due to the recent return of the applicant to the EU zone from the US, this propo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'An integrate numerical and experimental study of the dynamics and time scales of crystallizing magma systems' in the context of a Fourth Framework call.

assistant: **Objectives**

The main objective is to contribute to the understanding of the dynamics of differentiation in large magma chambers. We will evaluate the importance of crystal settling in the formation of a chemically stratified solid. A major aim is to provide a physical model of crystal nucleation and growth that relates the thermal and chemical history of the chamber to the final crystal size. The novelty will be to test the results of numerical models with laboratory experiments which will consist of cooling a solution from above to generate crystals that can settle in a well-controlled thermal regime. We will evaluate the variation of the crystal size in different regimes as a function of the temperature and the liquid composition. We hope to provide a flexible numerical model applicable to geologically realistic boundary conditions, and capable of relating the thermal history of magma chambers to field data on crystal sizes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'NEw CLEAN TEChnologies in the agrofood Sector.' (CLEAN-TEC-SMES) under Fifth Framework.

assistant: **Objectives**

The agro-food sector shows a common problem in all its sub-sectors: waste management. The agro-food sector mainly generates solid and liquid wastes. There are more and more strict European regulations which control these emissions and which oblige the firms, generally SMEs, either to realise relevant investments, tube finish" for the final treatment of these wastes or to incorporate clean technologies in their processes. Thus, this sector is in an adequate moment for knowing, analysing, developing or incorporating new technologies to minimise its' wastes production. Thousands of agro-food SMEs have to face some specific problems such as: lack of information concerning regulations and new technologies, the need of personnel trained specialised on clean technologies and minimisation of the environmental impact, inexperience in collaborating with technological centres or universities and unawareness of the European national and regional aids supporting R&D and technology transfer.The present Accompanying Measure aims at sensitising the sector on environmental management by promoting the incorporation of clean technologies in order to increase SMEs competitiveness. The AM will analyse and validate the environmental needs and trends in the sector. It will identify the European clean technologies offer and those technologies most suitable to the firms' needs, which will be disseminated among the firms of participating countries. A workshop will be organised with companies and suppliers of technologies in order to promote international co-operation. The participation in Community RTD programmes will be encouraged and facilitated."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Analyzing emerging patterns of mortality through lifespan inequalities on a global scale' in the context of a Horizon 2020 call.

assistant: **Objectives**

Most countries experienced major increases in life expectancy in the second half of the 20th century. This progress has meant that people are living longer on average and, at the same time, ages at death have become compressed to a narrow band of ages within populations. In other words, ages at death have become more similar, or lifespan inequality has decreased as populations live longer. The research I propose is driven by three major objectives: 1) Pioneer a powerful, theory-based methodology to analyze how age-specific patterns of mortality drive changes in life expectancy and lifespan inequality (variation in age at death), 2) Apply these methods to analyze recent patterns of life expectancy and lifespan inequality in low mortality countries, including Europe, and 3) Expand terms of discourse about the effects of violence on population health by analyzing a neglected perspective, namely lifespan inequality in contexts of high violence by sex. The data used in this project come from open-access databases, including the Human Mortality Database, the Global Burden of Disease, and the Global Peace Index. This project is timely because recent trends in several countries indicate that continued improvements in longevity are not inevitable, with stalls in life expectancy occurring in some low mortality countries, such as the UK and USA, and increasing premature mortality resulting from violence in contexts such as Latin America and Middle East. These recent dynamics indicate increasing complexity underpinning population health improvements and highlight the need to analyze population health through the lens of lifespan inequality. This has significant implications for policy, as it reveals emerging forms of inequalities that highlight the importance of adopting inequality
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Gender aspects in medical education in comparison to european medical education programmes' (GAIME) targeting Fifth Framework.

assistant: **Abstract**

This proposal shall enable medical professionals to develop new concepts for curricula and medical education under the aspect of gender dimensions in medicine. The study will support the development in the field of the socio-economic knowledge base. It shall act as an example for further examinations or studies and set sings for other medical schools / universities. Results of women's studies and gender studies being subject of sociology, history and public health will be transferred into medical education and medical research. A data base will be available on the net to ensure communication flow between groups dealing with medical problems and gender aspects as well as international contacts. As European partner Prof. Lesley Doyal from Bristol, UK, will co-operate with our institution to establish gender studies in medical education.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Novel tools for  crystallisation of macromolecules' (TOPCRYST), addressing dissemination and exploitation.

assistant: **Impact**

The elucidation of 3-dimensional structures of proteins and other biological macromolecules and complexes is essential for rational drug design, targeting and delivery, biocatalysis, the design of environmentally friendly agrochemicals, the development of biosensors and other nanobiotechnological applications. The most powerful tool for structural analysis is X-ray crystallography, which crucially depends on growth of high diffraction quality crystals. Crystallisation is the least controllable and usually rate-limiting step of the process that goes from cloning a gene to using the structural information for predicting and designing function. TOPCRYST, an academia-industry project, will use Dual Polarimetric Interferometry, pioneered by Farfield Scientific Ltd., to probe crystallisation at its earliest, most crucial stages. This will allow to predict the outcome of crystallisation trials when they are still at their earliest stages and thus to rationally design such experiments in order to lead them to the desired result, i.e. well-diffracting crystals. Transfer of knowledge between academia and industry will tackle the problem of detecting crystal nucleation phenomena at the very earliest stages of crystallisation and holds a number of promises that will be investigated in its course: (i) to guide the choice of pH and buffer, temperature, precipitating agent, additive(s) etc, starting from a limited number of preliminary experiments, thus obviating the need for extensive screening; (ii) to allow to unequivocally distinguish crystalline from amorphous material, something which is not always easy even for an experienced crystalliser, with obvious possibilities of extension to high-throughput environments; (iii) to allow optimisation of conditions under real-time control;
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Towards absolute safe and sustainable biobased textile' to be submitted under Horizon Europe.

assistant: **Abstract**

The textile value chain comprises a multitude of materials, a wide variety of end users and challenging final applications. There is a shift towards a more sustainable textile value chain, but it is slow and needs more innovative technologies to combat challenges such as low recycling rates, substitution of substances of (very high) concern and chemical pollutants. The project Towards safe and sustainable biobased textile (BioSusTex) has the objective to demonstrate rapid development of several key technologies which will have a significant impact on the textile value chain, a need highlighted by key industrial partners within the consortium. Focusing on cotton and cellulosic textiles BioSusTex targets increased recycling rates and substitution of harmful compounds by (i) delivering an optimized cellulosic fiber recycling process for dope-dyed man-made cellulosics, (ii) develop efficient and sustainable pre-processing techniques for removal of elastane, dyes, and impurities from post-consumer blended cellulosic textile, while avoiding potential toxic degradation products during processing (iii) develop a biobased PFAS-free water-repellent coating based on an innovative methodology with temporary surfactants  and (iv) developing removable biobased, PVC-free print formulations.  Significant improvements in these key technologies, in accordance with the Safe and Sustainable-by-design (SSbD) framework, are expected to notably improve the sustainability of the textile value chain. Further, BioSusTex will not only yield technical solutions but respond to the industry needs of rapid assessments methods by (v) further developing analytical methods and prediction tools related to toxicity evaluation (vi) building a novel Decision Support software tool implementing the SSbD metho
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Intelligent Micro-Manufacturing Processes' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

There is an increasing demand by medical, energy, commercial and aerospace applications for miniature parts with micro-scale features. Being a versatile way of fabricating micro-scale parts on a wide range of materials, mechanical micro-machining can effectively address the demand. In micro-machining, features are machined by mechanically removing material from the workpiece using micro-scale cutting tools (micro-endmills, micro-drills, micro-grinders) rotated with high speeds. To have a better control on dimensional accuracy, and to have savings in space, power and cost, micro-machining is performed on miniature machining centers (MMCs). Micro-machining cannot be utilized with its true potential today since the repeatability and efficiency of the micro-machining processes are limited due to the static and dynamic deflections (vibrations). The research objective of this proposal is to improve the accuracy and repeatability of mechanical micro-machining processes by incorporating model-based predictive control to MMCs. Model predictions will be used to drive the MMC actuators to minimize the static and dynamic deflections during micro-machining. The controller will calibrate the model parameters according to sensor measurements of tool deflection and cutting forces. The performance of the intelligent micro-machining process (IMMP) will be evaluated by fabricating micro-scale features on a wide range of materials. The subject of this proposal is novel since it will be the first attempt to perform research in application of model-based predictive control in mechanical micro-machining. If the project becomes successful, accurate and repeatable intelligent machining processes will be developed, and will be used for fabricating micro-scale parts.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'deCiphering tHE chemo-mechanical CrosstalK between Macrophages And Tumor cElls' in the context of a Horizon 2020 call.

assistant: **Objectives**

Pietro Mascheroni received his training in applied mathematics and mechanics in Italy and has carried out his research in the United States and in Germany. His work lies at the interface between applied mathematics and biology and has been published in prominent journals of the field. He is requesting funding for two years to work with Giovanni Cappello and join his group at LIPhy Grenoble, France. The scientific aim of the project is to improve the understanding of macrophage response to external cues, with the final goal of drawing new insights into the mechanisms of action of immunotherapies. The action will investigate the influence of chemical and mechanical signals on macrophage migration, analyzing their respective importance in determining cell behavior. Taking advantage of the host laboratory’s expertise and facilities, dynamic light scattering will be employed to monitor macrophage migration in 3D scaffolds and tumor aggregates. Macrophages will be stimulated by using different growth factors and chemokines, under variable oxygen and glucose culturing conditions. Mechanical stress will be applied using microfluidic tools and exploiting the osmotic action of Dextran on the extracellular matrix. Relying on the applicant’s expertise, theoretical models based on the active gel theory will be developed to assist the understanding of experimental results. Throughout the project the medical implications of the research will be considered, by taking advantage of collaborations with clinicians of partner institutions. The training program of the action is exhaustive and will allow the researcher to grow as a world-class leader in this field, which is fundamental in healthcare for the benefit of society. He will develop a unique blend of knowledge and expertise, allowin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Design of ModProtease through High-Throughput Screening Technologies for Therapeutic Applications' (ModProtease).

assistant: **Innovation**

The integration of ModProtease with antibody-based systems represents a promising strategy for targeted cancer therapy, particularly in addressing the challenges posed by KRAS mutations. These mutations are notoriously difficult to target directly with antibodies due to their involvement in intracellular signalling pathways and the development of resistance mechanisms. Strategies to overcome these limitations could include the development of protease-antibody conjugates and these conjugates might be directed to cleave specific substrates within tumour microenvironment, thereby enhancing the therapeutic effect of the antibody while minimizing off-target effects. However, engineered proteases remain underrepresented amongst protein-based biopharmaceuticals. This situation is due to fundamental challenges that exist in redirecting the substrate specificity of proteases. We propose a high-throughput screening platform that employs monoclonal hydrogel microbeads containing target substrates with FRET-based detection systems allowing for the precise identification of protease activity. This enables the rapid evaluation of various ModProtease variants and their effectiveness when conjugated to antibodies. The interplay of the SpyCatcher-SpyTag system enables the efficient and specific conjugation of ModProteases to antibodies, facilitating the creation of potent antibody-protease. Following high-throughput screening using fluorescence-activated bead sorting (FABS), the platform facilitates the recovery and analysis of protease genotypes from the microbeads. The group of Prof. Hollfelder (University of Cambridge) has substantial expertise in high-throughput methods and regarding the biology of proteases and protein binders. These conditions make the Host laboratory ideal for th