RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Changing worldviews at the end of the European Bronze Age: Societal insights from technology and lifeways before and after the Mycenaean palatial collapse in Greece (1300-1000 BC)'.

assistant: **Concept**

Established Mycenaean palatial systems collapsed during generalised socio-political crises in the eastern Mediterranean at the end of the Bronze Age. Fundamental questions about the social impact of these irreversible transformations remain with implications for fully understanding diachronic human responses to significant environmental and cultural stressors. Changing World aims to evaluate how social collapse interfered with cultural processes as expressed in metallurgy and lifeways. I will examine 150 metal objects (warrior equipment, jewellery, tools, utensils) microscopically, elementally, and isotopically from 5 key sites in Greece (Elateia, Lefkandi, Pefkakia, Voudeni, Nichoria) for investigating resource management strategies, metalworking choices, and supply networks during 1300-1000 BC. I will then integrate the metallurgical results with bioarchaeological data (aDNA, stable isotopes) on relatedness, sex, and diet from >300 individuals from Elateia and Voudeni to shed light on changing worldviews embodied in craft practices. This transdisciplinary methodology will offer new theorised multi-proxy insights that will directly inform ongoing academic debates about the nature of the Mycenaean collapse, and will open new pathways for future research on materials and humans, and for the study of societies in crisis. This project is now possible through combining my extensive analytical skills and access to highly representative, newly available study materials, Prof. Stockhammer’s (PI; LMU) recent and ongoing bioarchaeological research in Greece, and Prof. Degryse’s (secondment PI; KU Leuven) expertise in metals provenancing. My analytical (MC-ICP-MS) and theoretical training (Practice Theory) and critical understanding of aDNA data, alongside additional training in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Mutations of mtDNA - inheriting without perishing'.

assistant: **Concept**

Mutations of mtDNA cause mitochondrial diseases and are heavily implicated in the pathophysiology of age-associated diseases and ageing. Low levels of mtDNA mutations are universally present in somatic tissues of all humans and mtDNA mutations have been reported to contribute to age-associated diseases. Somatic mutations of mtDNA often arise during the massive mtDNA replication in embryogenesis and can accumulate postnatally by clonal expansion. Furthermore, ongoing mtDNA replication during adult life also contributes to the burden of mtDNA mutations in mammalian somatic tissues. Mammalian mtDNA is maternally transmitted without germline recombination and this asexual mode of transmission should theoretically lead to a mutational meltdown over generations, the so-called Muller ratchet. At least two poorly understood mechanisms in the maternal germline counteract the transmission of mutated mtDNA from mother to offspring, i.e., the bottleneck mechanism and purifying selection. The bottleneck mechanism ensures that only a fraction of the pool of mtDNA variation in the mother is transmitted to the offspring. The purifying selection functionally tests mtDNA and decreases transmission of mutations. In this proposal we will use powerful mouse models and completely new experimental strategies to study how mammalian mtDNA mutations are inherited and how somatic mtDNA mutations contribute to age-associated disease and ageing. Maternally inherited pathogenic mtDNA mutations often cause life-threatening incurable diseases with failure of multiple organs in humans. Unfortunately, the principles for inheritance of pathogenic mtDNA mutations are often unclear and the knowledge generated in this proposal will give a better basis for genetic counselling. Furthermore, the mechanisms cou
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Integrated High-Temperature Electrolysis and Methanation for Effective Power to Gas Conversion' (HELMETH) under Seventh Framework.

assistant: **Objectives**

The objective of the HELMETH project is the proof of concept of a highly efficient Power-to-Gas (P2G) technology with methane as a chemical storage and by thermally integrating high temperature electrolysis (SOEC technology) with methanation. This thermal integration balancing the exothermal and endothermal processes is an innovation with a high potential for a most energy-efficient storage solution for renewable electricity, without any practical capacity and duration limitation, since it provides SNG (Substitute Natural Gas) as a product, which is fully compatible with the existing pipeline network and storage infrastructure.The realisation of the P2G technology as proposed within HELMETH needs several development steps and HELMETH focuses on two main technical and socio-economic objectives, which have to be met in order to show the feasibility of the technology:•Elaboration of the conditions / scenarios for an economic feasibility of the P2G process towards methane as chemical storage, without significantly deteriorating the CO2-balance of the renewable electricity.•Demonstration of the technical feasibility of a conversion efficiency > 85 % from renewable electricity to methane, which is superior to the efficiency for the generation of hydrogen via conventional water electrolysis.Within HELMETH the main focus lies in the development of a complete pressurized P2G module consisting of a pressurized steam electrolyser module, which is thermally integrated with an optimized carbon dioxide methanation module. The HELMETH project will prove and demonstrate that:• the conversion of renewable electricity into a storable hydrocarbon by high-temperature electrolysis is a feasible option,• high temperature electrolysis and methanation can be coupled and thermally integrated to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'A MULTILINGUAL CONTINUOUS VIDEO DISCLOSING TOOL, BASED ON SUBTITLE INDEXING AND PARTIAL TRANSLATION'.

assistant: **Innovation**

POP-EYE will combine subtitle recognition, natural language indexing and partial translation to develop a film and video indexing tool. These multilingual indexes can then be used by broadcasting companies to help producers locate, retrieve and reuse video fragments. This will open up new markets for customers by providing better, cheaper and faster access to video material. The availability of subtitles comes from the provision of film and video material for viewers with hearing difficulties and from the use of subtitling, rather than dubbing, to present foreign language video material in some countries. POP-EYE will extract complete scripts from the subtitles using format conversion. It will then build multilingual indexes to these scripts using full text indexing, phrase indexing and partial translation.Indexing and retrieval of multimedia material is time consuming and expensive. Time consuming because much of it has to be done manually, and expensive because it has to be done by specialist experts. There are no systems that can watch and interpret moving images, nor systems that can listen to and understand spoken text. Tools are needed to help TV producers find video and film fragments for new productions, such as documentaries and training programmes. Information systems for archiving multimedia have been taken up slowly by industry. The main reason is that they do not automate the most expensive and time consuming activity which is profiling. Profiling involves attributing features to multimedia objects so that they can be successfully retrieved. These features cover 'non-contents' descriptions which include the author, date, publisher and addressee, 'contents' descriptions which include index keywords and class codes, and judgements which concern its usefulness
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Blanking simulation using HPCN technology' (BLANKSIM) under Fifth Framework.

assistant: **Objectives**

The blanking sector is demanding a new design cycle in which all trials will be computational and not experimental. Blanking is a computational intensive problem, so the use of HPC is recommended. However, this cycle cannot be applied because there are not commercial tools for blanking process simulation. The main aim of BLANKSIM is to transfer the blanking simulation technology into a forging and a sheet metal company, GSB FORJA and DOISTUA, and produce a commercial blanking tool. It will be adapted to run with Parallel Forge3 and installed using the distributed memory PC network of these industries. The new blanking tool could be used by any forging or sheet metal company, where punching or piercing processes are involved. Objectives:The main aim of BLANKSIM is to transfer the blanking simulation technology into a forging and a sheet metal company, GSB FORJA and DOISTUA, and produce a commercial blanking tool. For this purpose the following improvements should be done to the prototype developed in SIMTE project:- Link it with Parallel Forge3, to reduce computational time - Extend the prototype to cold processes - Improve the prototype in the following aspects:a) Elements removal in the cut area b) Improve the damage modelAdditional industrial objectives related with this one are the following: - To Take up of a blanking HPC tool in a forging and a sheet metal company: GSB FORJA and DOISTUA.- To assess the potential increment and benefit of GSB FORJA and DOISTUA competitiveness by introducing blanking HPC methodologies into its design phase.Work description:In the first Workpackage, WP1 - Management, the overall management activities of the project will be carried out.In WP2 - Definition of Industrial Requirements, the end user will define the requirement that the simu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Evolutionary explanations for cooperation: microbes to humans' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Cooperation poses a problem to evolutionary theory because it can be exploited by selfish individuals. Evolutionary biologists have developed a detailed theoretical overview of possible solutions to the problem of cooperation. In contrast to our theoretical understanding of potential solutions, however,, we have been relatively unsuccessful at applying theory to understand observations of cooperative behaviour nature. We present a novel and interdisciplinary programme of research to address this problem by empirically testing assumptions and predictions of several leading explanations for cooperation. We will develop theory to make explicit testable predictions for specific systems. We will exploit the advantage offered by different study systems: experiments with bacteria, comparative studies on cooperative breeding vertebrates, and experiments on humans. In addition to addressing specific hypotheses, we will show how evolutionary theory links and differentiates explanations for cooperation across various taxa and levels of biological organization.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Neoantigen Identification with Dendritic Cell Reprogramming'.

assistant: **Innovation**

In cancer, genetic mutations result in production of tumor neoantigens restrictively expressed in transformed cells and serve as ideal molecular targets for cancer vaccines and adoptive T cell therapies. However, available methods for the identification of clinically relevant neoantigens driving potent anti-tumor immunity are highly inefficient. Thus, there is an urgent need for innovative solutions to identify powerful immunogenic neoantigens to unlock the full potential of immunotherapy and treat currently untreatable cancers. The NeoIDC platform has the radical vision to use the type 1 conventional dendritic cell (cDC1) reprogramming technology, arising from the ERC-funded project TrojanDC, to directly identify highly immunogenic tumor neoantigens and neoantigen-specific T cell receptors (TCRs) for the development of powerful cancer vaccines and adoptive T cell therapies. To achieve this, we will firstly identify tumor peptides presented on MHC class I and II by cDC1-reprogrammed cancer cells and validate immunogenicity in vivo. Secondly, we will expand neoantigen-specific T cells by co-culture with reprogrammed cancer cells, sequence TCRs and link to cognate neoantigens. This will facilitate the generation of potent cancer vaccines and tumor-reactive T cells for adoptive transfer. Experimental activities with collaborators and clinicians will be coupled with exploitation plans including partnership with Asgard Therapeutics, ensuring commercialization by generation of novel IP, broad and targeted dissemination and a new start-up company.NeoIDC combines cDC1’s antigen processing and presenting abilities with the unique mutational profile of cancer cells to enable the direct identification of immunogenic neoantigens and cognate TCRs. Ultimately, this project will enabl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Nephrops trawl discard reduction using activating selection grids'.

assistant: **Objectives**

The overall objective of the project is to develop a semi-rigid grid system to reduce the by-catch of fish and immature Nephrops (Nephrops norvegicus) from Nephrops trawl fisheries. The Northern North sea, Southern North sea, and the Aegean sea will be targeted. Species and size selection will be employed to reduce discard levels.Key Objectives.1. To develop a primary grid system to separate fish from Nephrops.2. To develop a secondary grid system to release immature Nephrops.3. To conduct fishing trials with a view to confirming discard reduction.4. To inform industry and receive advice from industry about the commercial viability of the researchINTRODUCTIONThe fishery, whilst having a high economic value, suffers from a large by-catch of undersize commercial fish species and other organisms. This can be up to half the live caught, comprising of a mix of un-wanted fish and under size Nephrops which can be as much as 60% by number for Nephrops discards. The reason for this high level of discarding is attributable the smaller mesh sizes permitted in Nephrops trawls as compared to white fish trawls. These fisheries can occur on the same grounds and a white fish by-catch limits often applies to Nephrops trawl fisheries.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Ultra Strong Materials'.

assistant: **Concept**

The theoretical strength of metals and ceramics is about 10% of their Young’s modulus. Although whiskers reach strength values close to this limit they cannot be used in the design of load bearing structures. Currently the typical strength of the structural materials in use is only in the range of few % of this theoretical limit. Premature plastic deformation and failure due to flaws are the main reasons for this distinctive lower limit. For engineering applications, adequate fracture toughness is required which permits a ductile behaviour and certain strength even in the presence of flaws or cracks. The strength of the strongest metallic materials is only 10 % of the theoretical limit. Increasing the strength of metallic high strength materials by a few percent is usually associated with an unacceptable decrease in fracture toughness and results in a very flaw sensitive strength similar to that known for ceramics. In pearlitic steel wires it was possible to overcome this 10% limitation significantly. In the last years for the first time a strength of 6.3 GPa was obtained for this material which is about 30% of the theoretical limit or 3 times stronger than other high strength steels. The group of the PI has shown that these wires have an exceptional toughness equivalent to a high damage tolerance. The proposed ERC-grant should permit the analysis of the phenomena for this superior combination of strength and ductility. The knowledge of the essential required architectural features of this nano-composite and the necessary properties of the individual phases as well as their interfaces will be used to design nano-architectures also in other materials to obtain such exceptional properties. The developed skill in the generation of nano-composites from coarse constituents w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Nanocrystalline silicon films for photovoltaic and optoelectronic applications' (NANOPHOTO) targeting Sixth Framework.

assistant: **Abstract**

The primary aim of this research project is to develop computational tools capable of assisting the design of a new nc-Si growth process with a Low Energy variant of a Plasma Enhanced Chemical Vapour Deposition (LEPECVD) reactor, addressed at the depositio n of nc-Si films for both photovoltaic and optoelectronic applications.This objective is for many aspects really at the frontier of the today knowledge of multiphase materials, and for this reason requires the involvement of different theoretical and exp erimental tools and expertises. An LEPECVD reactor is actually in full use in one of the partner's laboratories and has been already demonstrated to be a very powerful tool for high growth rate, high quality epitaxial silicon and silicon-germanium films . The modelling activities include Molecular dynamics (MD) and ab-initio calculations applied to the the simulation of the growth of nc-Si grains in a amorphous silicon (a-Si) matrix, to the evaluation of the best a-Si/ nc-Si ratio and the elastic/plas tic effects consequent to the presence of nanocrystals of silicon in the a-Si matrix and to the presence of a grain boundary phase, which could be responsible of unwanted carrier recombination processes.The computational tools will be also used to evalua te the band offset vs microstructure and strain, in view of the of the fine-tuning of the optoelectronic properties. As the computer modelling could not be granted for a complete forecasting of the role of process parameters on the local nanostructural a spects and associated physical properties, additional theoretical studies on quantum confinement will be carried out. Such theoretical studies will be based on the results of systematic measurements of optoelectronic properties of nc-Si.The development o f the computer m