RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Wood phenotyping tools: properties, functions and quality' under Horizon 2020.

assistant: **Concept**

The objective of TOPWOOD is to build a four-year scientific exchange program about the test and development of medium and high-throughput phenotyping measurement and analysis tools for selected basic wood properties in the laboratory and in the field (TOols for Phenotyping WOOD-TOPWOOD). The participants wish to exchange knowledge and experience for sharing and expanding skills, improving existing tools and developing new original measuring devices for wood properties involved in studies of wood quality and of wood biological functions. The phenotyping tools and methods of analysis developed and improved in TOPWOOD are intended to be used by the participants to investigate the genetic and environmental determinism of key wood properties involved in forest tree adaptation, as well as in wood production and wood quality for the forest and wood industries. The participants of TOPWOOD are three academic institutions and one private company from three European Union countries, Austria, France and Spain, and one third country, Argentina. TOPWOOD WP1 is dedicated to the measurement of basic wood properties involved in wood quality (using near infrared spectroscopy, microdensity and ultrasonic approach). WP2 aims at studying and developing measuring devices for wood functional traits (wood hydraulic conductivity, vulnerability to cavitation and the dynamics of wood formation). WP3 aims at developing, discussing and disseminating data analysis methods dedicated to the large and complex data sets generated by these measuring devices. Finally WP4 is dedicated to coordination, management and dissemination.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Identification of the protein interactome of the A2A-adenosine receptor' (ADENOSINE-RECEPTOR) targeting Seventh Framework.

assistant: **Abstract**

The A2A-adenosine receptor is a Gs-coupled receptor, which has several unique structural and functional characteristics. Recently, the C-terminus of the receptor has been appreciated as a binding site for several “accessory” proteins, of which only half a dozen are established. It is clear that (i) this list cannot be exhaustive and (ii) that all these proteins cannot bind simultaneously to the receptor. The challenging, but very important task is to document which of all these interactions do occur in the living organisms. Here we propose to meet this challenge by characterizing the interactome of the A2A-receptor by using a two-step proteomics approach; i.e., the receptor will first be expressed in tagged versions in cells, which can be differentiated into neurons. This will allow for optimization of the conditions and for an initial survey of interaction partners; subsequently, we intend to generate mice, in which the receptor has been engineered to afford the isolation of receptor-complexes from native tissues, in particular the striatum. To the best of our knowledge, the proposed strategy has not yet been pursued with other GPCRs. Thus, if successful, it may set a precedent and provide the proof-of-principle for the entire family of GPCRs. At the very least, the current approach provides the ‘acid test’ for all purported interactors of the A2A-receptor.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'A holistic multi-actor approach towards the design of new tomato varieties and management practices to improve yield and quality in the face of climate change' under Horizon 2020.

assistant: **Concept**

The world demographic growth and global climate change are major challenges for human society,hence the need to design new strategies for maintaining high crop yield in unprecedented environmental conditions.The objective of TomGEM is to design new strategies aiming to maintain high yields of fruit and vegetables at harsh temperature conditions, using tomato as a reference fleshy fruit crop.As yield is a complex trait depending on successful completion of different steps of reproductive organ development, including flower differentiation and efficient flower fertilization,TomGEM will use trans-disciplinary approaches to investigate the impact of high temperature on these developmental processes.The core of the project deals with mining and phenotyping a vast range of genetic resources to identify cultivars/genotypes displaying yield stability and to uncover loci/genes controlling flower initiation,pollen fertility and fruit set.Moreover,since high yield and elevated temperatures can be detrimental to quality traits,TomGEM will also tackle the fruit quality issue.The goal is to provide new targets and novel strategies to foster breeding of new tomato cultivars with improved yield.The main strength of TomGEM resides in the use of unique and unexplored genetic resources available to members of the consortium.It gathers expert academic researchers and private actors committed to implement a multi-actor approach based on demand driven innovation.Tomato producers and breeders are strongly involved from design to implementation of the project and until the dissemination of results.TomGEM will provide new targets and novel strategies to foster the breeding of new tomato cultivars with improved yield under suboptimal temperature conditions.TomGEM will translate scientific insigh
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Western Balkan Countries Inco-Net Support in the field of ICT' (WINS-ICT).

assistant: **Concept**

WINS-ICT aims to strengthen S&T cooperation between the EU and the Western Balkan countries by deepening the bi-regional strategic relations in the field of ICT and promoting the participation of WB ICT research actors in FP 7.<br/>The objectives of the WINS-ICT project are to<br/>- Provide comprehensive understanding of the current framework of EU-WBC ICT RTD policies and RTD collaboration<br/>- Optimize the current policy framework and establish strategic partnerships with other projects, such as WBC-INCO.NET<br/>- Support the building of sustainable networks between innovative WBC ICT researchers and their EU counterparts<br/>- Enhance the capacities and capabilities of WBC researchers to successfully participate in the FP7 ICT research activities<br/>The WINS-ICT project will thus contribute to the Commission's priority to extend future EU-Western Balkan S&T co-operation by promoting WBC involvement in the ICT programme at multiple levels comprising support to the regional and bi-regional dialogues, capacity building at the regional and national levels, and targeted dissemination strategies. The political dimension will in particular be closely intertwined with the WBC.INCO-NET project, and will further entail regional dialogue and regular information exchange with ICTC members and other EC Directorates General. The ultimate aim is to fully integrate researchers from the region into networks of FP-active EU organizations and enable their related research organisations to submit their own project proposals as coordinating institutions. The main output of the project will be an improved policy dialogue in the field of ICT, reflecting the WBCs needs and priorities in future ICT Work Programmes and thus providing the ground for enhanced participation from the target reg
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Accurate Intravenous Therapy for Every Patient' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Intravenous (IV) therapy involves administration of fluids or medications through a needle or a catheter and it is administeredto over 90% of hospitalised patients. Although a simple procedure, a balanced IV therapy has a significant impact byreducing the number of complications by 59% and the length of hospital stay by 3.4 days. Currently the everyday IVtreatment is administered manually and monitored visually as the infusion pumps that offer accurate treatment monitoringare very expensive and complicated to use, making them suitable only for emergencies.A Finnish SME, Monidor, has developed high-accuracy IV infusion monitoring device based on patented technology thatuses infra-red light beam drop calculation and specific measurement algorithms. This allows to offer state-of-the-art accuracyin a simple and cost effective form bringing balanced IV therapy to every bed in the hospital. Additional features such astouch-screen interface and wireless connectivity will help to lower the associated workload for the medical staff.Monidor has been developing the technology for the past two years and has reached a prototype device currently defined atTRL7. The technological excellence has been tested with Oulu University Hospital and user needs studies have beenconducted with medical staff in Finland, UK, Italy and Denmark. The company has a strong team of 8 experts includingdoctors and engineers with experience in R&D and business development from companies such as Nokia, Microsoft andBroadcom.Monidor is now looking to conduct the feasibility studies in order to finalize the development process and introduce the novelsolution to the market. As a result of the proposed project Monidor will have a validated technology development plan, IPRstrategy for EU-wide technology exploitat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The Neurobiology of Social Context-Dependent Stress Responses' (NotSOSTRESSED) under Horizon 2020.

assistant: **Objectives**

Sociability –an individual's tendency to engage in group interactions– is a fundamental property of life. Recently, sociability has been identified as a strong mortality predictor in humans. Although affecting health, we lack an understanding of the biological mechanisms underlying sociability. I here propose that the presence of others modulates an individual's response to an environmental stressor. Being evolutionary conserved, I will investigate the sociability neurocircuitry in the model system Drosophila melanogaster. I will tackle this by focussing on 4 objectives: WP1) Delineation of sensory cues and receptors modulating social context-dependent stress responses through behavioural analysis of candidate receptor gene mutations, targeted RNAi and pheromonal bioassays, WP2) Identification of neurons processing sensory information relevant to stress by functional investigation of the neurocircuitry connecting mechanosensory, pheromonal and temperature stress sensing through connectome, trans-Tango and optogenetic approaches, WP3) Mapping of higher brain stress-responsive foci integrating stressor and social information through Ca2+-imaging, WP4) Dissection of the hormonal pathway effectuating social-regulated stress responses via tissue-targeted genetic knockdown and overexpression of pathway components and stress response assays. Addressing key questions relevant to human health will bring scientific Excellence and Innovative advances to the current knowledge gap in Behavioural, Neuro & translational sciences which will be communicated to the scientific and general public. The fellowship will enhance my personal research potential and career perspectives by acquiring novel scientific and transferable skills, training of myself and others and increase my internation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Microglial control of neuronal activity in the healthy and the injured brain'.

assistant: **Concept**

Microglia are the main immune cells of the brain, but their role in brain injury is highly controversial due to the difficulties in selectively manipulating and imaging microglial actions in real time. Specifically, it is unclear whether microglia control neuronal survival after injury via shaping the activity of complex neuronal networks in vivo. To this end, we have combined fast in vivo two-photon imaging of neuronal calcium responses with selective microglial manipulation for the first time. Our data suggest that microglia constantly monitor and control neuronal network activity and these actions are essential to limit excitotoxicity and neuronal death after acute brain injury. We also identify microglia as key regulators of spreading depolarization in vivo. However, the underlying mechanisms remained unexplored. Here, I propose that microglia control neuronal excitability and based on preliminary data I set out to investigate how this occurs. We will combine selective, CSF1R-mediated microglia depletion with advanced neurophysiological methods such as in vivo calcium imaging and intracranial EEG for the first time, to reveal how microglia shape activity of complex neuronal networks in the healthy and the injured brain. Then, we will study microglia-neuron interactions from the network level to nanoscale level using in vivo two-photon imaging and super-resolution microscopy. We will apply novel chemogenic and optogenetic approaches to manipulate microglia in real time, assess their role in neuronal activity changes and investigate the molecular mechanisms in vitro and in vivo. Our unpublished data also suggest that inflammation – a key contributor to brain diseases – could disrupt microglia-neuron signaling and we set out to investigate the underlying mechanisms. By
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Concrete matrices for high-cycle-fatigue resistant, eco-efficient infrastructure'.

assistant: **Innovation**

The necessity to meet the rising global demand for mobility and energy supply and, at the same time, the urgency to minimize the carbon footprint, leads to the challenging scientific question of the fatigue resistance of emerging eco-efficient concretes. Since existing knowledge of the traditional Portland-clinker-based binders is largely empirical, it cannot be directly transferred to new binder systems, exhibiting complex chemical and mechanical interactions within the heterogeneous material structure. In contrast to the well-established insight into the high-cycle fatigue of metals, a complete understanding of the fatigue degradation processes in concretes is still lacking. In this research, we are committed to pioneering an innovative approach that establishes a universally applicable link between the chemical/microstructural composition of novel concrete materials and their fatigue resistance. To create an interdisciplinary methodology for the scientific analysis of fatigue-resistant eco-efficient concretes, complementary competences of a multidisciplinary research team will be combined in a concerted application of physico-chemical modeling approaches of hydration processes and advanced methods of multiscale and multifield computational mechanics supported by machine learning and accompanied by a rigorous experimental validation program. The developed coherent methodical framework will include innovative theoretical and numerical as well as tailored experimental approaches covering all relevant spatial and temporal scales to enable realistic predictions of the fatigue behavior of existing and future eco-efficient concrete formulations. This is necessary to give design engineers confidence in the new materials, and to enable design concepts, optimally satisfying re
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Modern Methods of Operator Algebras for Time-Frequency Analysis' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The project is on the interface between time-frequency analysis and  operator algebras.  In the last decade  the relevance of operator  algebras in time-frequency analysis and Gabor analysis has evolved  mainly due to the contributions of Groechenig, Janssen and their  collaborators.  The operator algebras that have appeared in these works  are twisted group C*-algebras or more generally crossed products. In  the present project the proposer wants to explore the deeper structure  of crossed products to gain some new insight about time-varying filters and  Gabor frames. The methods involved in these investigations are modern  methods from operator algebras such as groups of automorphisms,  projective modules over twisted group C*-algebras and the K-theory of  operator algebras. The proposer will invoke deep results of Arveson, Connes,  Elliott, Evans, Haagerup, Pimsner, Rieffel and Voiculescu obtained in  the study of noncommutative tori and irrational rotation algebras.  Another aspect of the proposal deals with varying the lattice of a Gabor  frame and the approximation of a continuous Gabor frame by  finite-dimensional Gabor frames. The work of Rieffel on strict  deformation quantization, continuous fields of C*-algebras and the  notion of quantum Gromov-Hausdorff distance will provide the correct  operator algebraic setting for these topics.  Coming from NuHAG and EUCETIFA the candidate is at one of the  sources of research in time-frequency analysis. The choice of the outgoing host institution UC Berkeley is dictated by the concentration of operator analysts there. In particular the established scientific contacts to Rieffel will be very valuable. After the return to Europe the insight obtained will be further developed in cooperation with the researchers there, and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Vortex microflow inducer that enables detection of ultra-low concentrations of species in sensors' (2021-2027).

assistant: **Innovation**

According to WHO, in 2018, more than 100,000 chemicals were released into the global environment due to their production, use, and disposal. In this regard, water is the key element for their effective transport in the food chain and since remediation can be extremely difficult, such pollution is leading to acute or chronic toxicity in aquatic organisms, loss of habitats and biodiversity as well as human diseases. But, industrial wastewater flows contain hazardous and toxic species that are not easy to process, and treatment installations need extremely reliable and sensitive sensing solutions to continuously monitor the efficiency of the side stream treatment processes. At the same time, the world population is increasingly depending on aquaculture for nutritious food. Frequent analysis of the water quality is essential and needs to be performed at  point-of-testing, not in remote laboratories. The common challenges in environmental control, wastewater management and aquaculture are that, in small sample sizes,  species need to be detected that are present in very low concentrations, with a technique that can be performed at point-of-testing, at low cost and in a minimum of time. In the last decade, new sensor technologies have emerged that can meet these challenges. These sensors however require the sample to flow over the sensor surface and, importantly, detection is only possible if the target species in flow makes contact with the sensor surface. This is one of the key technological hurdles that todays microfluidics sensors have not overcome yet. In VORTEX SENSOR vortices will be induced in the flow channel with acoustic streaming, an approach which was developed in ERC Starting Grant EVODIS. This will enable long range transport of compounds towards the sensor sur
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Deep understanding and modelling of the hierarchical structure of Prosody', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The prime objective of the ProsoDeep project is to gain a deeper understanding of the language of prosody through the analysis of all the levels in the production hierarchy of prosody. In particular, it will exploit the benefits of the top-down and bottom-up approaches through their incorporation within a Deep Prosody Model (DPM). The DPM will facilitate the advancement of speech technologies that rely both on the synthesis of prosody, e.g. text-to-speech (TTS) systems, and its analysis, e.g. speech emotion recognition (SER). To reach this objective the project will draw on a variety of scientific fields, including signal processing, physiology of prosody production and biomechanics, linguistics, and machine learning, and will also be augmented with respiratory measurements.