RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Inhibition of Cancer by Disrupting Interaction Between Polo-like Kinase 1 Polo-box Domain and Spindle Targets' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

Despite a significant progress in the therapy of various cancers, currently used medicines lack the necessary efficacy and selectivity. Conventional chemotherapy uses drugs that attack all dividing cells thus killing not only cancerous cells but also vitally important healthy dividing cells. There is an urgent need for novel approaches and methods to treat various cancers.Polo-like kinase 1 (Plk1) is found to play a critical role in the development of ovarian, prostate, pancreatic, breast and other cancers. Plk1 has been validated as a mitotic cancer target for a number of years. However, the standard approach, inhibitor design for the ATP binding site of Plk1, turned out to be ineffective due to the lack of specificity. Plk kinases contain Polo-box domain ( PBD) that binds phosphopeptide motif present in many proteins, essential for mitotic progression. Since PBD is essential for Plk1 function and localization, drug design can be targeted specifically at Plk1 and not other proteins. We propose to analyse in several ways if the PBD can be validated as a drug target. First, analyse PBD function in mammalian cells using RNAi and genetic rescue approach. Second, design and synthesize inhibitors for PBD and analyse their effect on cancerous cells. Design will be carried out in silico using molecular modelling program written in collaboration with the software company.Third, analyse other members of Plk family, namely, Plk2 and Plk3, which are quite different from Plk1 in terms of expression and function in mammalian cells and their role in cancer and the function of their PBDs is not yet established. The proposed research is highly interdisciplinary, combining the advanced knowledge of experimental molecular and cell biology. Research will be carried out in close collaborat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Anotec Real-time MOdel for Noise Exposure of Aircraft', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The main objective of the work proposed here is to provide a detailed specification and design for  a new level of aircraft noise prediction modelling, capable of being used in real-time applications. This model can thus be used for the minimisation of the noise impact “on-the-fly” as part of a wider optimisation for minimum environmental impact of aircraft operations, as envisaged in SGO/MTM.In recent years increased effort has been dedicated to better understand the interdependencies between noise and emissions. In Europe initiatives like TEAM-PLAY have been setup in order to create a toolsuite with which these interdependencies can be assessed. However, these efforts are mainly directed towards long term assessments, usually for policy support, informing the rulemaking process, e.g. for the assessment of stringency options or elaboration of action plans. These methods do not intend to   be accurate at single event level. ARMONEA, however, will provide a tool with which each individual aircraft operation can be optimised for minimum noise impact in dependence of current air traffic/meteo situations, thus significantly contributing to minimising the environmental impact of air traffic.ARMONEA is based on the SOPRANO platform, a complex aircraft noise source prediction program, developed in EU projects and at present the main common tool for aircraft noise predictions in Europe. Its flexibility allows for its adaptation to a variety of appliations, and it is envisaged that the power of SOPRANO will greatly contribute to the success of ARMONEA.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Entrepreuneurship in the mountainous areas of southern Europe' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Economic diversification is widely recognized as a key factor for the advancement of lagging regions. The aim of this research is to analyze entrepreneurship in the secondary and the tertiary sector of the mountainous areas in Southern Europe and to identify variables which work towards fostering or inhibiting it. Drawing on relevant literature on entrepreneurship and its impact on rural development, in general and on the development on lagging regions, in patricular, the project involves six interrelated research objectives. OBJECTIVE 1 is to analyze the history and the characteristics of the establishments and the background of entrepreneurs. OBJECTIVE 2 is to assess the sources and the availability of business capital both working and start-up. OBJECTIVE 3 is to analyze the role of local leadership in stimulating entrepreneurial behavior. OBJECTIVE 4 is to assess the influence of Macro variables sush aw government policies on taxes, regulatory compliance, labor cost and availability and the influence of Micro variables such aw information, communication, existence of sub-contractor services on business growth and performance. OBJECTIVE 5 is to identify support and incubator organizations, to analyze their performance, and to assess the attitudes of entrepreneurs towards the importance, the availability, and the need for provision of instruments by these organizations.  OBJECTIVE 6 is to provide guidelines for the advancement of entrepreneurship in the mountainous areas of Southern Europe.   The proposed study will involve five mountainous areas in Greece, France, Italy, Spain, and Portugal Information on the establishments and the background of business owners in the study-areas will be collected surveying up to 150 business active in the fields of production/process
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Heuristics and Biases in Debt Managment'.

assistant: **Innovation**

Managing a debt portfolio requires complex decision making and is particularly challenging in the current climate of economic instability. Faced with various debts and diverse interest rates, consumers must decide the amount to allocate and the order in which to settle their debts. Issues of debt management also impact financial institutions such as banks and credit companies who need to understand how their borrowers prioritize their payments to be able to estimate the probability that their loans will be paid back. This research program aims to identify heuristics and biases that affect consumers when managing their debts. We examine when debt behaviors are aligned with normative strategies and when they lead people to make predictable but irrational decisions. Using versions of interactive debt management games as well as other experimental methods the program is designed to achieve three main goals: (1) identify sources of suboptimal debt management (Studies 1-2) (2) expand our understanding of the processes underlying debt management decisions (Studies 3-4), and (3) explore techniques to direct consumers toward more optimal debt management strategies (Studies 5-6). Along with its theoretical contribution, the proposed research program has important practical implications. Understanding how people perceive and manage their debts will allow financial organizations to create tools and procedures to assist their clients in managing their loans, and improving the rationality of their debt repayments.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Pulsed Dipolar Spectroscopy on Symmetric Oligomers' to be submitted under Seventh Framework.

assistant: **Abstract**

Pulse EPR distance measurements have evolved to a standard tool for generating long-range constraints for structural modelling via pulsed dipolar spectroscopy. Especially the pulsed electron−electron double resonance (PELDOR or DEER) method is becoming increasingly applied. The method is particularly promising for structural studies on different functional states of membrane proteins which are difficult to access by most biophysical methods.However, in samples of membrane proteins several approximations commonly made in data analysis might not be well met. The effect of the finite sample concentration is not necessarily as straightforward as in homogeneous solutions. Furthermore, systems of singly-labelled monomers forming trimers or higher oligomers not only allow extracting the oligomerisation state from the modulation depth, but also exhibit multi-spin effects hampering the distance analysis which are often neglected. These multi-spin effects should increase significantly with oligomeric state.In the proposed project we will address these problems and develop and validate alternative approaches to data acquisition and analysis in symmetric multi-spin systems.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Secure Authentication of Products for Everyone'.

assistant: **Innovation**

Scantrust offers breakthrough anti-counterfeiting technology and an accompanying software platform to grant brand owners and consumers high security and active traceability.  Unlike regular QR Codes, Scantrust’s patented and proprietary Secure QR Codes  (named SQRCodes) have intrinsic protection against counterfeit attempts. The SQRCode can be placed on any product, and allows anyone to authenticate a product and find out about its traceability. This scalable innovation seamlessly integrates with standard, widely used systems and devices used by: businesses in production and distribution (QR codes, internal software systems); the packaging industry (standard digital printers); and consumers (smartphones) in order to empower each user at any stage of a supply chain to instantaneously verify a product.


**Keywords:** Supply chain management,Product packaging,Counterfeiting
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Network of European Research Infrastructures for Earthquake Risk Assessment and Mitigation' (NERA) under Seventh Framework.

assistant: **Objectives**

The overall aim of NERA is to achieve a measurable improvement and a long-term impact in the assessment and reduction of the vulnerability of constructions and citizens to earthquakes. NERA will integrate the key research infrastructures in Europe to monitor earthquakes and assess their hazard and risk, and will combine expertise in observational and strong-motion seismology, modeling, geotechnical and earthquake engineering to develop activities to improve the use of infrastructures and facilitate the access to data. NERA will ensure the provision of high-quality services, including access to earthquake data and parameters and to hazard and risk products and tools. NERA will coordinate with other EC projects (SHARE, SYNER-G) a comprehensive dissemination effort.NERA will contribute to the OECD GEM program and to the EPOS ESFRI infrastructure.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Shadowing, Omega Limit Sets and Internal Chain Transitivity in Dynamical Systems' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

This project aims to bring Dr Jonathan Meddaugh, one of the most promising young dynamicists of his generation, to the University of Birmingham to work with Dr Chris Good on a project that aims to capitalize on recent exciting developments in the theory of dynamical systems.  Key to the analysis of dynamical systems are the asymptotic behaviour captured by limit sets and an understanding how computed (approximate) orbits correspond to true orbits, i.e. how pseudo-orbits are shadowed by real orbits. In recent work, Meddaugh has shown that shadowing is closely linked to characterizations of limit sets in terms of internally chain transitivity developed by Good and his collaborators. This project will develop the general theory behind these links and, using innovative applications of non-Hausdorff topologies and symbolic dynamics, make significant contributions to our understanding of shadowing and limit sets in a  number of important families of dynamical system, such as shift spaces and polynomial maps on their Julia sets. During the project Meddaugh will develop the professional skills that will place him in an ideal position to secure a leading academic position.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Development of an automatic process of in-house collection, storage and application of adaptive bacteria culture for fish farms' (ADAPOND), addressing dissemination and exploitation.

assistant: **Impact**

Evidence from recirculation systems shows that new starters experience 30-80% loss in sales almost unavoidably in the first year during the adaption period of a biofilter, accompanied by the failure losses from fish medication and seasonal depressions counting summingly for more than €70-90M annually in Europe. Low reliability of biofilter systems are considered the main reason why people avoid entering fish farming business. Our idea is to reduce the bio-filter recovery time after failure by developing an Intelligent Biofilter Control (IBC) system. Real-time monitoring system will detect the viability and metabolic activity of the bacteria culture. At healthy period excess bacteria are extracted, prepared for storage and stored by automatic collection system. In case of biofilter failure, the stored culture will be cultivated for rapid recovery of the biofilter thereby providing increased productivity of the farm. The major barriers to overcome are: (a) Biofilter start-up and recovery processes in fish farm are slow, taking 3-6 weeks. (b) Methods of bacteria extraction and storage are designed for usage in laboratory and not providing the efficiency required for industrial applications; (c) Limited knowledge about how is the recovery performance of recultivated bacteria related to the health before collection; (d) Existing methods to assess the viability and metabolic activity of bacteria are complicated and time consuming. We intend to overcome these barriers by speeding up the recovery of a bio-filter by recultivating the stored adapted bacteria. Farm productivity will increase up to 15%; Farm supply security will improve, increasing the sales price about 5%, there is less environmental risks, and less hazard to fish health. Process for automatic extraction of the ba
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Innovative Catalytic Technologies & Materials for Next Gas to Liquid Processes' (NEXT-GTL) under Seventh Framework.

assistant: **Objectives**

The project addresses from one site the most critical and costly step to produce liquid fuel from natural gas using conventional routes, e.g. the stage of syngas production, and from the other side explores alternative routes to convert natural gas to liquid transportable products.  The general objective is to explore novel and innovative (precompetitive) routes for transformation of natural gas to liquid products, particularly suited for remote areas to facilitate the transport. The aim is an integrated multi-disciplinary approach to develop in a long term vision the next-stage catalysts and related precompetitive technologies for gas to liquid conversion,  in fully consistence with the indications of the call. For this reason, we have excluded to consider as part of the project catalytic technologies, such as FT synthesis and hydrocracking. In addition, we have excluded to investigate coal to liquid, both due to environmental impact of the use of coal, and to focus R&D. We have thus focused the project on three cluster lines: 1.  new, not conventional routes for catalytic syngas formation from natural gas which include steps of separation by membrane and eventual reuse of byproducts; 2. direct catalytic conversion of methane to methanol/DME; 3. direct catalytic conversion of methane to aromatics under non-oxidative conditions followed by upgrading of the products by alkylation with ethane/propane.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Targeting BMP4 and BMPR1a for imaging of esophageal adenocarcinoma' (BMP4EAC) under Seventh Framework.

assistant: **Objectives**

Within BMP4EAC we aim to investigate the commercial feasibility of our newly discovered and highly specific antibodies against BMP4 and one of its receptors, BMPR1a, for imaging applications in oncology. BMP4 and BMPR1a are highly expressed in esophageal adenocarcinoma (EAC) and other tumors as well as their metastases. The specificity, strong binding capacity, rapid clearance, high tissue penetration level, and flexibility of our antibodies is unprecedented and makes them highly suitable for in vivo imaging applications.The opportunity: The current methods for evaluation of disease stage consist of diverse modalities, including, CT and PET-CT scans, and ultrasonography. These techniques have major limitations to accurately detect metastasis and are inadequate for monitoring disease response. In the clinical setting we foresee applications of our proprietary technology in the non-invasive diagnosis of tumors and metastases with high expression of BMP4 and/or BMPR1a (e.g. EAC), identification of patients with high chance to respond to BMP4 inhibitors, follow tumor progression during treatment, and facilitated localization of small metastases during surgical treatment. Furthermore, the labeled antibodies can be used to investigate the efficacy of novel therapeutic agents by following tumor progression in animal models in a research setting.The project and expected outcomes: Within the ERC PoC we will explore the commercial feasibility by in vivo validation experiments as well as by performing essential research for the formulation of a business proposition, strengthening our IP position, and developing a sound business plan. These activities will result in a proposition package that will be used to present the commercial potential to investors and other strategic partners
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Task-Enhanced Peer Interaction for Morphosyntactic Development in Young EFL Learners: A Cognitive-Interactionist Perspective' (TEPIMoD-YELL) targeting Horizon Europe.

assistant: **Abstract**

The project Task-Enhanced Peer Interaction for Morphosyntactic Development in Young EFL Learners: A Cognitive-Interactionist Perspective (TEPIMoD-YELL) investigates how peer collaboration and task repetition can support children’s grammar development in foreign language classrooms. Despite the increasing interest in task-based approaches, research on young learners’ second language acquisition remains scarce, particularly regarding morphosyntactic features such as articles, past tense morphology, and subject–verb agreement. Addressing this gap, the project examines how task-enhanced peer interaction contributes to accuracy and long-term learning gains.The study adopts a quasi-experimental mixed-methods design with 40–60 learners aged 9–12 in bilingual and CLIL contexts in Spain. Quantitative data will be collected through pre-tests, post-tests, and delayed post-tests, while qualitative analyses will focus on classroom interaction, corrective feedback, and uptake. Individual differences such as working memory and proficiency will also be examined, providing a deeper understanding of the cognitive and social factors that shape learning.Expected results include robust empirical evidence on the effectiveness of peer interaction and task repetition for young learners’ grammar development. These findings will advance theoretical debates in second language acquisition and provide practical guidelines for curriculum design and teacher education.The fellowship will also enhance the researcher’s expertise in applied linguistics, research management, and open science practices, contributing to her long-term career development and to the wider dissemination of innovative, evidence-based approaches to language teaching.


**Keywords:** Second Language Acquisition; Task-Based Languag