RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Scenarios for the evolution of the european science and technology policy' (EUROPOLIS) targeting Fifth Framework.

assistant: **Abstract**

In order to help promoting and bringing depth to a debate on Europe's science and technology, we propose a project which will aim at conceiving and discussing possible institutional scenarios for a further evolution of Europe's S&T policy, and with respect to its content major new orientations and initiatives for its evolution. It will be focused on three main objectives:-Assessing the future evolution (1999-2010) of the political, socio-economic context of the European science and technology policy and its potential Impact; -Assessing transformations of the science and technology institutions;-Taking into account those assessments, building policy institutional scenarios for the future of the European science and technology policy (new mechanisms, new tools, new kinds of institutions, etc). The output of the project will take the form of position papers and reports on the various issues presenting analyses and scenarios. They will be discussed and cross-examined in workshops to which policy-makers will participate.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Science and applications of random polymer fiber lasers' (RANPOFIL) under Horizon 2020.

assistant: **Objectives**

As a new type of light source, random  lasers have attracted many attentions. The non-directional and high threshold characters of the traditional RL systems have largely limited their application. The effect of one-dimensional confinement on the lasing properties of a classical random laser system has obtained, bringing about the birth of random fiber lasers  with low threshold and directionality based on the stimulated emission in the disorder system. Laterly, the new random fiber laser, based on a Rayleigh scattering amplified via the Raman effect  in the silica optical fiber  without a cavity formed only by a random distributed feedback, have been reported. However, the backscattering coefficient of silica optical fiber is very low, which induces high pump threshold and long fiber length. Interestingly, optical fibers  with two merits come into my research points in the random fiber lasers: (1) high Rayleigh backscattering coefficient; (2) high negative thermo-optical coefficient fiber. Therefore, the new polymer fiber random laser will be greatly to enhance the efficiency and tunable of random lasing. These studies will provide scientific and technical evidences and pave the way for better random fiber laser.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Nouvelles technologies microbiennes appliquees a l'elevage en circuit ferme et diversification en aquaculture continentale (perche et gardon/rotengle)' (1994-1998).

assistant: **Concept**

Considering the rapid growth of the demand in aquaculture products, the need to diversify the production and the pressure to reduce the impact of aquaculture on the environment, optimisation of new species intensive culture, combined with the improvement of technologies applied to recirculating systems has been identified as an necessity for the further development of European freshwater aquaculture. The general industrial and economical objective of the present project is the development of a transnational production chain of high value freshwater fish (perch, roach/rudd) mainly oriented towards the food market. The proximate objective is to demonstrate the feasibility and profitability of these productions in an industrial type recirculating system in order to develop an aquaculture engineering activity. Short term objectives are the transfer of technologies towards fish farms using the recirculating system, and the export of newly developed know how. Presently, the grow out farms of perch and roach/rudd do not dispose of a continuous supply in high quality weaned juveniles, due to inadequate techniques of weaning and absence of control of the reproductive cycle and the health environment. Moreover, the growth performances of these species in recirculating systems are relatively poor, due to a lack of knowledge in their nutritional requirements and inadequate techniques of recirculation. Research must be conducted to optimise the performances of the rearing system and the culture techniques.The first research axis consists to develop in situ weaning practices adapted to the juvenile monoculture production in small ponds. New microbial technologies will be experimented in recirculating systems in order to control the quality of the physico- chemical and health (sanitat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Studying Gravitational Lensing Magnification with PAU and other Surveys' under Seventh Framework.

assistant: **Concept**

I plan to study the large-scale magnification of galaxies and quasars due to gravitational lensing, advancing the technique of magnification measurement for the purpose of investigating dark matter and dark energy.  In particular, I will work on detecting the lensing mass autocorrelation function by studying galaxy-galaxy correlations in three dimensions, and I will also work to develop quasar magnification analyses using variability as a new and useful technique in studying large scale structure.  These projects combine aspects of gravitational lensing, large scale structure, and quasar physics research.  In order to facilitate these and other analyses, I plan to take a leading role in the calibration of the Physics of the Accelerating Universe (PAU) survey, a Spanish collaboration set to start taking data in 2012.  The survey is designed for the optimal ground-based measurement of three-dimensional galaxy correlations, which will allow for the first measurement of the lensing mass-mass correlation function as well as precise measurements of the galaxy-mass and galaxy-galaxy correlation functions.  These results will place valuable constraints on cosmological parameters describing the behavior of dark matter and dark energy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Information system for Marine Aquatic Resource Quality', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

i-MARQ will deliver real-time information on coastal water quality into a variety of end-user markets, via a dynamic GIS-based system. The project will develop and validate advanced data fusion, modelling and management algorithms to generate high-quality data content. The system will support decision-making by various end-user groups including:Citizens concerned about environmental quality in recreational waters;Local authorities seeking a quality tourism cachet and wishing to avoid hazard to public health;Companies seeking to validate environmental performance and avoid liabilities from pollution incidents.Objectives:The goal of the project is to develop and validate a prototype GIS-based system which can deliver information on environmental quality of coastal waters. Market analysis has identified a significant demand for such information by a variety of users. To achieve this, the project will:First, develop data processing technologies able to generate information from heterogeneous data sources and dynamic models, according to defined user requirements;Second, integrate the above within a real-time GIS under a scaleable data management framework;Third, validate and evaluate the above with selected users and with reference to a dedicated horizontal user group.Work description:The project will be carried out in 10 main workpackages (WPs), of which:WP1 will be dedicated to the management;WP2 will develop a users' specification and establish evaluation benchmarks. This will enable;WP3 to define the i-MARQ architecture and establish a technical specification for the system modules;WP4, WP5 & WP6 will then develop the innovative technological modules which can generate the information content. Specifically, WP4 will define the data management protocols to permit data as
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'QSEIF: The new pathogen, DNA and immunological testing platform' to be submitted under Horizon 2020.

assistant: **Abstract**

iMiCROQ aims to bring to the market the first integrated platform for pathogen, immumological and PCR testing speciallydesigned to cover the whole needs at farm level, internal control laboratories, food processors and point-of-care infectiousdisease testing. Thanks to its affordability, QSEIF will allow from SMEs to large companies to improve their biosafety andinternal microbiology control to fulfil their requirements from ISO 22000, BRC or IFS certifications, while reducing the needsin laboratory space, the investment, the test cost and man-hour involvement thanks to higher automation. Another importantbreakthrough in the immunological sector is that QSEIF provides 1-2 orders of magnitude lower limit of detection, less timeand better dynamic range than current reference test ELISA. We envision three important applications of this disruptiveplatform in the areas of: (1) Food Safety; (2) Vaccination Control; (3) Immunoassays for human and animal diagnosis. Wewill reach end-users from all these sectors according to different commercial strategies that have been tailored to suit eachtype of customer.The main objective of this project is to increase the technical maturity of the platform and to validate its performance andoperability in operational environment with different end-users. After this 24 months project, we will lauch QSEIF to themarket with the aim of becoming an international reference in the diagnostic market. The viability of the technological,regulatory, market and financial aspects of the QSEIF innovation project were assessed through a feasibility analysis carriedout in SME Instrument Phase I. From the analysis, we expect to install 717 devices that would perform 5.2M tests in a fiveyear period. By then, QSEIF platform will bring an accumulated Net Profi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Defining the Mechanisms of gp78 as a Master Regulator of Ubiquitin E3 Ligase in Membrane Protein Quality Control.', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The ubiquitin-proteasome system (UPS) is responsible for the degradation of approximately 80% of proteins, enabling precise control of protein quality and maintaining protein homeostasis within the cell. Over the past four decades, a comprehensive understanding of the regulatory mechanisms governing the UPS, particularly concerning various cytosolic and nuclear proteins has been developed. However, there remains significant knowledge gaps regarding how membrane proteins, which account for one-third of human proteins and serve as targets for 70% of FDA-approved drugs, are regulated by the UPS. The specificity of the UPS is dictated by E3 ligases, which bind to substrates and execute ubiquitination. gp78 is the master regulatory ubiquitin E3 ligase for membrane proteins, enabling rigorous control of membrane protein quality and participating in various pathways. gp78 not only works with the biogenesis factors to form a detection center responsible for targeting misfolded proteins but also cooperates with the E2 enzyme and several quality control factors to promote recognition and ubiquitination of a wide range of important substrates, leading to their degradation via the proteasome. Yet remaining questions abound:  How does gp78 detect misfolded proteins? What are gp78's substrates and their biological functions? What structural mechanisms underlie the recognition and ubiquitination of membrane substrates by gp78?This proposal aims to combine state-of-the-art approaches in structural biology and biochemistry, cell biology, and chemical biology to systematically dissect the underlying molecular mechanisms by which the gp78 membrane protein quality control hub, mediates substrate detection, recognition, and ubiquitination.The project will advance our understanding of how ce
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Advanced 3d visualization of human brain structure and activation'.

assistant: **Innovation**

This project aims at the further development of the methods used in the analysis and interpretation of functional brain images obtained by positron emission tomography (PET) or functional magnetic resonance (fMR) imaging. This research will be of value for both clinical work and other physiological research studies on the brain. This project will also develop a virtual environment that will provide tools for a full 3D interactive real-time display of medical image. This environment, based on advanced 3D computer graphics (virtual reality) will facilitate the dialogue between Mds, engineers and physicists. All necessary data for development and evaluation will be supplied by collaborators at the department of Neurology at the university hospital of Copenhagen.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Toward Tough Glasses with Controlled Nanoscale Heterogeneities'.

assistant: **Concept**

Specialty glass manufacturing is annually a €30 billion industry worldwide and transparent oxide glasses are one of the most important engineering and functional material families owing to their unique features, such as tailorable physical properties. However, at the same time, intrinsic brittleness continues to be their main drawback, which severely restricts many applications. In the proposed project, we will explore the possibility to improve the fracture toughness and damage resistance of oxide glasses through controlled nanoscale phase separation, as the presence of inclusions can lead to crack deflection or trapping. The size of these heterogeneities needs to be small enough (<50-100 nm) to maintain transparency. To this end, we will tune the composition of calcium aluminosilicate glasses to enable controlled phase separation with respect to the size and composition of the nano-domains (Work Package 1). Then selected mechanical properties (stiffness, hardness, fracture toughness, and crack resistance) of these new glasses will be explored (Work Package 2). These experiments will be guided by a combination of atomic scale (molecular dynamics) and microstructural scale (peridynamics) simulations (Work Package 3). The project will provide the scientific breakthrough for elucidating the toughening mechanism induced by phase separation and its impact on macroscopic crack propagation.The complementary expertise of the applicant and supervisor and the research and training environment provided by the host organization (Aalborg University, Denmark) will ensure the achievement of this timely and innovative project as well as the dissemination and exploitation of the expected results. These research outputs will accelerate the design of new fracture-resistant glasses, which
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Probing the effect of Time Reversal Symmetry breaking by the application of a local magnetic field in topological insulators' under Seventh Framework.

assistant: **Concept**

Electronic states that could propagate long distances without power dissipation and with spin coherence (i.e. without losing information about their spin state) would be desirable for the design of energy efficient electronic devices and to make reality theoretical proposals of quantum computation devices. Topological insulators are recently discovered materials that may potentially offer these foreseeable properties.  These materials are insulating in bulk, but present metallic edge states that are naturally preserved from backscattering by time reversal symmetry. In other words, the propagation direction and the spin state are correlated in these systems, so in order to be scattered, electrons must flip their spin (break time reversal symmetry). Experimental results already indicate the existence of such states but still a huge experimental effort is necessary to reach the necessary understanding and the technical skills to take advantage of the predicted surprising properties of these materials. Specially promising are the expected consequences of the application of a local magnetic field to these topologically protected states. Between other consequences, this would allow the confinement and manipulation of these states and would be therefore a first step towards the fabrication of theoretically proposed devices based in the special properties of these materials. We propose here a comprehensive study of the effect of magnetic field in different topological systems (HgTe quantum wells and the so called 3D topological insulators) by means of state of the art nanofabrication and characterization techniques, including an innovative combination of scanning probe microscopies and electronic transport measurements. Our aim is to provide a complete (local and non-local) pic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Interrogating Basolateral Amygdala Activity during Social Behaviour at Single-Cell and Population Levels' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The accurate perception and interpretation of social stimuli is crucial for survival in social species including rodents, primates and humans. Before deciding whether to mate, fight or avoid, an animal must process multisensory cues to activate an internal representation of the social environment that answers key questions (Sex? Age? Friend? Foe? Previously encountered?). Little is known about how the brain develops and activates this representation. We will focus on the role of neuronal firing in the basolateral amygdala complex (BLA) in processing and integrating social cues.In the first stage of this research, we will use neuropixel silicon probes to conduct large-scale recordings of the BLA in rats during social interaction with conspecifics (juvenile rats, male rats and female rats). We can record from large populations of neurons across weeks in freely-moving rats during social interaction. Second, by analysing the activity of single neurons in the BLA, we can characterize the specificity and responsivity of single neurons to social interaction and understand the mitigating factors (gender of conspecific, sexual receptivity, age, previous history). Third, we can decode the population activity of the BLA during social activity to understand how BLA connectivity changes during social interaction and with experience. Finally, we will use optical tagging of anatomically-defined ensembles of BLA neurons to understand how BLA projections code for specific properties of social activity. Success in this project will provide an understanding of how neural computation occurs within the BLA.