RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Correction of the atmospheric phase noise in interferometric radio-astronomy by water vapour radiometry', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

We will develop a novel system to account for and counteract atmospheric phase noise in millimetre wavelength, radio-astronomical observations, in a quest to boost sensitivity at higher frequencies and higher spatial resolutions. Our innovative approach makes use of specially built, 22 GHz receivers that monitor the atmospheric water vapour content and provide input to a sophisticated model of the atmosphere directly above the telescope. The model will be used to rid the astronomical data of undesired atmospheric effects. World-class technology and methods will be developed with the intention to satisfy the needs of the current as well as the next generation of millimetre interferometric designs.As an initial result of our work, we anticipate a significant increase in the sensitivity of current millimetre interferometric observations, especially under unfavourable atmospheric conditions. Research and testing will be conducted using the facilities of the Institut de Radioastronomie Millimetrique (IRAM), in Grenoble, France. We will initially implement our system at the Plateau de Bure Interferometer, one of the world's most sensitive millimetre radio telescopes, with a view to implement it at other observatories worldwide in the future. IRAM, an international research organisation supported by German, French and Spanish funds, belongs in the category of small/medium-sized enterprises (SMEs).Equally important to the scientific goals of this project, is the aim to provide training to the applicant in the fields of interferometric methods in radio astronomy and atmospheric physics. This training will be complementary to the past experience of the applicant, Dr Karastergiou, and will result in diverse knowledge and expertise in his field.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'New tools for delivering therapeutic proteins: application to human therapy' (HUMPROTHER).

assistant: **Innovation**

There is a worldwide pent-up demand for the development of new technologies to allow rapid medical diagnostic and specific human therapy. One of the major challenges now is to develop delivery systems, which are convenient and effective for tackling problems in disease treatments. We have developed two new strategies aiming at producing and delivering biotherapeutic proteins.The first one is based on the use of polypeptide transduction carriers to directly deliver therapeutic proteins into mammalian tissues and cells. We have recently isolated and characterised two new natural polypeptides transduction carriers, which have the capacity with a high efficiency to directly traverse biological membranes. We anticipate that these membrane permeable proteins will represent a new class of transduction carriers and may have important functions in protein therapy for cancer and infectious diseases.The second one focused on in vitro protein synthesis technologies for producing recombinant proteins. We have recently demonstrated the effectiveness of a cell-free expression system in production of membrane proteins directly coupled to liposomes. Our technology for producing membrane proteins represents an original and powerful approach to produce immunogenic proteoliposomes fo r the development of new vaccines delivery systems and therapeutic proteoliposomes for human diseases.The long-term objective of this proposal is to provide new vectors for biologically relevant vaccines and delivery of therapeutic proteins and also, to in crease our potential in therapeutic strategies. These biological vectors will be checked for their transduction properties by testing therapeutic protein candidates on human diseases models. This original approach represents a unique system that would allow
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'A new approach to revealing the composition of kimberlite melts and their deep mantle source' (KimberliteNewApproach).

assistant: **Concept**

The overarching aim of this project is to provide novel constraints on the composition of the Earth’s deep mantle, particularly its volatile content, by undertaking an innovative geochemical and isotopic study of the deepest formed melts on Earth: kimberlites. Kimberlite melts are derived from depths in excess of 150-200 km. They are important as the major host of diamonds and because entrain xenoliths (i.e. fragments) of upper mantle and deep crustal rocks during ascent to the surface, providing a major source of information about the geochemistry of the deep Earth. Despite their importance, the composition of primary kimberlite melts and their exact mantle source are hotly debated issues. This is due to contamination of kimberlite melts by mantle and crustal rocks during magma emplacement and near surface alteration of primary kimberlite mineralogy.To determine the composition of primary kimberlite melts, I will employ a novel approach that combines radiogenic (Sr-Nd-Pb) and stable (C-O) isotope fingerprinting of melt inclusions in kimberlitic magmatic minerals (i.e. olivine and spinel), using innovative ultra-sensitive techniques. This approach will constrain if the carbonate-dominated melt inclusions truly represent examples of pristine kimberlite magma by quantifying processes like crustal contamination and degassing that may have altered the melt composition. I will investigate kimberlites from targeted localities from different parts of the world (South Africa, Canada, Greenland, Russia) and of variable age (Proterozoic to Cretaceous) to assess if there are spatial and/or temporal controls to kimberlite composition. The melt inclusions C-O isotope data, coupled with O isotope analyses of kimberlitic olivine, spinel and perovskite, are designed to test if recycled
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Pilot manufacturing line for production of highly innovative materials' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The vision of PilotManu is the upscale of the current mechanical alloying technological facility into a powder manufacturing pilot line by further developing existing IPR-covered results owned by the SMEs in the consortium related to mechanical alloying technology and to innovative powder materials for different applications.The baseline technology that will be upscaled from a technological facility status into pilot scale, is the High Energy Ball Milling machine, able to deliver innovative materials for new product lines developed by SMEs and industrial partnership that will lead the technological upscale.The project will demonstrate the technological and economical viability of the pilot line by implementing advanced materials into coatings, abrasive tool and additive manufacturing applications.Additional application sectors will be represented in the business cases by analyzing the cost/benefits of using the following new materials: Mg hydrides for hydrogen storage, thermoelectrics for energy harvesting, flame retardant textile and polymer nanocomposite for rapid prototyping.The potential impact brought by the new HEBM pilot production will be transversal also in all those technological sectors demanding high performance and outstanding material properties not achievable by conventional products. These huge un-exploited knowledge reservoir related to materials produced via HEBM or Mechanical Alloying will be unlocked by the Pilot Manu production system able to bring these results into the market.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Next-generation intensified chemical processes integrating plasma and single-atom catalysis'.

assistant: **Concept**

PRIME LEAP tackles the grand challenge of advancing sustainable, efficient, and electrified chemical processes by focusing on the conversion of methane, a primary component of natural gas and a by-product of steam cracking, into a diverse portfolio of value-added chemicals through synergic plasma and catalysis technologies. Current progress in this sector is hindered by a shortage of trained engineers and scientists capable of designing intensified chemical processes that integrate innovative approaches such as plasma chemistry and advanced catalysis. PRIME LEAP seeks to bridge this gap by fostering a new generation of experts equipped to drive these transformative advancements and address the critical needs of the chemical sector.The project integrates cutting-edge plasma technologies, single-atom catalysts, data-driven intelligent process control, and life cycle assessment to equip doctoral candidates (DCs) with deep technical knowledge and cross-disciplinary expertise in plasma physics, chemical catalysis, methane activation, and process integration and optimization, enabling them to develop and implement next-generation methane-to-chemicals technologies. Through this multidisciplinary approach, that brings together leading academic institutions, research centers, and industrial partners, PRIME LEAP aims to cultivate a cohort of skilled professionals who can develop next-generation process intensification solutions and address the challenges of resource efficiency and carbon neutrality in the chemical industry.Overall, PRIME LEAP supports the transition toward greener, more efficient chemical methods and the project aligns with the EU’s climate goals to enhance resilience and innovation in the process industry.


**Keywords:** plasma chemistry; methane conversion; si
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Multipurpose Force Tool for Quantitative Nanoscale Analysis and Manipulation of Biomolecular, Polymeric and Heterogeneous Materials' to be submitted under Sixth Framework.

assistant: **Abstract**

FORCETOOL (FT) proposes to develop a multipurpose tool for quantitative nanoscale analysis and manipulation of biomolecular, polymeric and heterogeneous surfaces. Key features of the proposed instrument are 1 nm spatial resolution and 1 pN force se nsitivity; operation in technological relevant environments (air or liquids) and with no impact on the sample surface.The multifunctionality and flexibility of FT will enable characterization, control or manipulation of structures on a nanometer-scale, s o it will open new approaches for manufacturing at molecular and nanoscale levels. This tool is based on two innovative concepts : (i) the bi-modal AFM and (ii) the multimaterial methodolody. The bi-modal AFM concept considers the cantilever as a thre e dimensional object with several resonance modes, in particular two. The concept departs radically from the established principles of dynamic force microscopy (only the fundamental mode is considered). The double excitation allows to separate topogr aphy from composition contributions in the experimental data. Furthermore, the bi-modal AFM is about two orders of magnitude more sensitive to force variations than state of the art tapping mode AFMs. The multimaterial methodology will allow to tran sform the amplitude, frequency or phase shift changes measured by the instrument into quantitative information about the sample properties. The multimaterial methodology has both a general framework to describe dynamic force microscopy interactions an d specific codes to be used with different materials such as inorganic materials, biomolecules , polymers or molecular architectures. Specific key goals are: Topography, composition analysis and manipulation of biomolecules, polymers and hete rogeneous surfaces; operation in air or liquids
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Atomic-scale STudies Of the Nature of and conditions for Inducing Superconductivity at High-temperatures' (ASTONISH) under Seventh Framework.

assistant: **Objectives**

One of the greatest challenges these days in condensed matter physics is the fundamental understanding of the mechanisms leading to high-Tc superconductivity and ultimately, as a result of that, the discovery of a material system exhibiting a superconducting state with a transition temperature Tc above room temperature. While several different classes of high-Tc materials have been discovered in the past decades, including the well-known CuO-based superconductors (cuprates) or the more recently discovered class of Fe-based superconductors (pnictides), the mechanisms behind high-Tc superconductivity remain controversial. Up to date, no theory exists which would allow for a rational design of a superconducting material with a transition temperature above room temperature. On the other hand, experiments on rather complex material systems often suffer from material imperfections or from a lack of tunability of materials’ properties within a wide range. Our experimental studies within this project therefore will focus on model-type systems which can be prepared and thoroughly characterized with atomic level precision. The growth of the model-type samples will be controlled vertically one atomic layer at a time and laterally by making use of single-atom manipulation techniques. Atomic-scale characterization at low energy-scales will be performed by low-temperature spin-resolved elastic and inelastic scanning tunnelling microscopy (STM) and spectroscopy (STS) as well as by non-contact atomic force microscopy and spectroscopy based techniques. Transport experiments will be conducted by a four-probe STM setup under well-defined ultra-high vacuum conditions. By having access to the electronic and spin, as well as to the vibrational degrees of freedom down to the atomic level, we
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'A developmental engram for the organization of adult hippocampal circuits'.

assistant: **Objectives**

Most adult cortical dynamics are dominated by a minority of highly active neurons distributed within a silent neuronal mass. If cortical spikes are sparse, spiking of single distinct neurons can impact on network dynamics and drive an animal’s behavior.  It is thus essential to understand whether this active and powerful minority is predetermined and if true to uncover the rules by which it is set during development. I hypothesize that birthdate is a critical determinant of neuronal network function into adulthood.   More specifically, I reason that neurons that are born the earliest are primed to participate into adult network dynamics. The goal of this proposal is to challenge this original hypothesis, which is considerably fed by our past work aiming at understanding how cortical networks function and assemble during development. Hence, we have shown that an early birthdate: (1) specifies the specialization of GABA neurons with a hub function, that orchestrate perinatal network dynamics in the mouse hippocampus (Bonifazi et al. 2009) and develop into long-range projecting GABA neurons into adulthood (Picardo et al. 2011); (2) delineates a subtype of CA3 glutamate neuron with a “pacemaker” function in the absence of fast GABAergic transmission (Marissal et al. 2012).  We will analyze the structure and function of early born GABA and glutamate neurons, in the adult mouse hippocampus, mainly in vivo, where the extensive and long-range connectivity of these cells is preserved. To this aim, we have translated from the in vitro to the in vivo situation, our multidisciplinary method to investigate structure-dynamics relationship in cortical networks. Using this approach, we have recently shown that, in the absence of external landmarks, distance is encoded within the hippoc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Modelling lianas as key drivers of tropical forest responses to climate change' in the context of a Horizon 2020 call.

assistant: **Objectives**

Tropical forests are essential components of the earth system. Yet, much uncertainty exists about the exact role of this biome in the global carbon cycle. Our limited understanding of tropical forest functioning is reflected in uncertain global vegetation model projections. A large source of uncertainty in these models is their representation of ecosystem demographic processes. Interestingly, fieldwork has revealed lianas as important components of tropical forests, which are apparently increasing in abundance. Liana proliferation might be a key adaptation mechanism of tropical forests to climate change, which has potentially large impacts on the long term tropical forest biome carbon balance. Nevertheless, no single terrestrial ecosystem model currently includes lianas. TREECLIMBERS will generate important insights into the mechanisms by which lianas influence the carbon balance of tropical forests, by building the first vegetation model that includes lianas. We will make the first integrative study of (1) the contribution of lianas to instantaneous carbon and water fluxes, (2) liana contribution and influence on canopy structure, (3) their role for long term demographic processes, and (4) of their role in forest responses to drought events. TREECLIMBERS will develop the first liana plant functional type (PFT) by combining a unique global meta-analysis of existing data with innovative terrestrial LiDAR 3D measurements of the canopy to study the contribution of lianas to the canopy structure. New and available data will be integrated in the Ecosystem Demography (ED) model, a forerunner of the next generation of vegetation models. By using model-data fusion we will, for the first time, integrate the large amount of available and emerging liana data, leading to an integra
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Effects of mental disorders on the wellbeing and prosperity of family members and friends' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Mental disorders have an enduring impact on individuals wellbeing and economic prosperity. Although it is often assumed that these effects extend to the wellbeing of family members and friends as well, comprehensive large-scale direct investigations have rarely been conducted and it remains unclear how enduring these influences are. This project addresses this fundamental gap in our understanding and substantially extends prior knowledge in two crucial ways. First, I will estimate how much a person?s mental disorder affects the wellbeing and prosperity of family members, including parents and siblings. Second, I study whether these effects extend to partners in later adulthood. Third, I will assess the broader social impact of mental illness across the life course, also estimating the longevity of these wider harmful influences. My research team and I will use several interlinked nationwide Finnish registers to answer these questions. The linked datasets contain rich individual-level information for over three decades for the whole Finnish population, including complete details of healthcare utilization and prescription medication prescribing for approximately 5 million persons over a 20-year observation period. The main advantage of these nationwide registers is that they are truly population-based and free of the biases that are common in research surveys. My team will use state-of-the-art research designs and statistical methods to identify potential causal links. MENTALNET will deliver cutting-edge knowledge on how mental disorders coalesce in social networks, which can potentially help to reduce the societal impact of mental disorders.


**Keywords:** mental disorders, well-being, life course, intergenerational, socioeconomic, social ties, social network, register-