RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Characterisation and Identification of Cell Engulfment Receptors on cDC1s.' in the context of a Horizon Europe call.

assistant: **Objectives**

The engulfment of dead cells by type 1 conventional dendritic cells (cDC1s) is essential to maintain tolerance to self-antigens and to induce immunity to infected or malignant cells. cDC1s have the unique ability to engulf dead cells, in contrast to the closely related cDC2s. Moreover, uptake of apoptotic cells induces cDC1 maturation and serves as their key source of antigens. However, we still do not understand which receptors on cDC1s are involved in the recognition and internalisation of dead cell corpses and whether these receptors differ depending on the type of cell death (e.g. apoptosis vs necrosis) that led to corpse formation. Remarkably, our preliminary data indicates that cDC1s, unlike macrophages, 1) do not express many of the classical or canonical engulfment receptors, 2) they tend to nibble pieces from dead cells and 3) are able to ingest parts of live cells. Hence, in the proposed work, I aim to characterise live, apoptotic and necrotic cell engulfment by cDC1s and its phosphatidylserine-dependency using novel reagents and state-of-the-art instrumentation such as high-resolution live cell microscopy. Furthermore, I will use a validated CRISPR-editing protocol and establish a CRISPR screen with both primary and immortalized cDC1 cell lines to discover which receptors on cDC1s are necessary for the engulfment of live, apoptotic and/or necrotic cells. Lastly, I will interrogate in vivo the role of key cDC1-dependent phagocytic receptors in a tumour and tolerance model using novel markers for DC maturation that I identified during my PhD. Altogether, the work in this proposal will elucidate a long-standing question in the DC and phagocytosis field, contribute to our knowledge on how cDC1s mediate anti-tumour immunity and tolerance, and may open new strategi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'How to deal with how you feel: Understanding and training context-dependent emotion regulation' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Emotion regulation refers to the variety of processes through which people attempt to influence their emotions. The ability to effectively regulate emotions is key to psychological wellbeing, and emotion dysregulation is a central element of mood disorders. The existing research tends to paint emotion regulation strategies as either adaptive or maladaptive, but increasingly researchers are beginning to realize that this characterization is an oversimplification. Instead, responding with the right strategy in the right context is key for adaptive regulation and, hence, for mental health. However, there is very little empirical investigation of how context shapes the use and effectiveness of emotion regulation strategies. In this application, we propose to first establish who uses what emotion regulation strategy when (i.e. the context) and to what effect, using innovative smartphone assessment methods to examine these processes in daily life. Second, we propose using this information about context as input to train people to use the right strategy at the right time using a smartphone application, with an aim to improve mental health.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Development on low temperature fuel cells withmethanol as a fuel option'.

assistant: **Objectives**

The objectives to be reached in the frame of this project are related to the development about low temperature fuel cells. The concerns to be developed are the following: - alternative materials as electrode catalysts in front of Pt, - new polymer membrane electrolytes, - improvement of selective oxidation and direct feeding of methanol for itselectrochemical conversion to hydrogen, - testing of the above developments at stack level. The work will be focussed at development of electrocatalysts that can be inhibited from poisoning of intermediates as CO, -COH, produced during oxidation of methanol, to an extent that the time variation of overpoten tial be less than lOmV/lOOOhr. Metallic conductors, such as Ruthenium oxides, have been know for several years to be very active catalysts in anodic and cathodic processes, keeping high electric conductivity and electrical stability, specually when blended with other oxides. On the other hand, the project will head at new polymers as alternative of the present expensive perfluorinated membranes, other than preventing transport of methanol from the anode to the cathode. The work will be achieved through sulfonation of conventional polymer materials, just like the preparation of ORMOLYTES from which new membranes could be prepared, expecting to get levels of conductivities greater than 1 ohm-1cmAn other main aim in this project will deal with the improvement of the electrochemical activities of methanol about its direct oxidation even at temperatures below 100øC, expecting to get current densities up to 400mA/cm2 at voltages of 0.5 V. The study will based on proton exchange membrane fuel cell type, with alternative platinum alloys (Pt-Ru) as ano de catalysts. In order to avoid the problem that represent the flooding of the system
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Adhesion Multiphysics of Rubberised Asphalt Binders' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

AMRAB aims to train a talented research Fellow through an interdisciplinary project focused on modelling the coupled adhesion multiphysics in the interfacial zone between crumb rubber modified binders (CRMB) and mineral aggregates under various environmental conditions. The primary deliverables of the project include a fundamental understanding of adhesion mechanisms, an accurate prediction framework and evaluation protocol for the adhesive properties of CRMB, and an implementation of industrial adhesion promoters and technologies in rubberised road construction. The Fellow will receive intensive technical training from both academic and industrial hosts, which will substantially extend his expertise from construction asphalt materials to a multidisciplinary field of chemistry (UoN), mechanics and computational modelling (Aston and KTH), experimental characterisation (UoN and RWTH) and road engineering applications (Total and AI). The Fellow will also receive inter-sectoral and professional skills training in project management, outreach, networking, and intellectual property protection. The benefits brought by AMRAB is represented by strengthening the EU industry leadership in adhesive material innovation and aiding the EU engineers in rubberised asphalt material selections, road structural design, and techno-economic analysis. The implementation of adhesion promoters and technologies for CRMB in rubberised road infrastructures will extend the road service life, increase the recycling of waste tires, and ultimately reduce the greenhouse gas emissions and consumption of petroleum bitumen. Uniquely, the project will enable the Fellow to obtain interdisciplinary knowledge and inter-sectoral complementary skills by building a new and exciting research field, which will pav
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Translational regulation of c/ebp alpha and c/ebp beta transcription factors. Implications for myeloid development and leukemic transformation' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

C/EBPa and B mediate tissue-specific gene expression, cellular differentiation and growth arrest. C/EBPB plays a central role in the differentiation of myelomonocytic cells and in their leukemic transformation. C/EBP function in transcription regulation is dependent on the relative level of two antagonising isoforms, a transactivating and a repressing isoform, both for C/EBPa and B. The synthesis of N-terminally truncated isoforms from internal start codons depends on an, evolutionary highly conserved, small upstream open reading frame (uORF) mediating delayed translation reinitiation. We hypothesise that this special mRNA structure senses translation initiation factor activity providing the mechanism for C/EBP isoform ratio modulation. We propose a detailed analysis of the relationship between C/EBPa and B mRNA structure and translation initiation factor activity especially of eIF-2 which is known to be a key factor for translation reinitiation. One of the mechanisms which might play a part in transformation is deregulation of translational control generating unbalanced C/EBP isoform ra
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Phase Change Material in District Heating with Model Predictive Control' in the context of a Horizon Europe call.

assistant: **Objectives**

Rapid escalation of building energy use has raised concerns all over the world, and existing predictions express that this increasing trend will aggravate energy crisis and serious environmental problem. The district heating (DH) system that incorporates renewables and the thermal energy storage component shows favorable prospects as a supplier to serve residential and commercial consumers for space heating and domestic hot water. The operation temperature of the DH system is becoming lower to achieve a more energy efficient, sustainable, and eco-efficient system. This trend results in the performance degradation of the thermal storage when integrating the water tank to the DH system, resulting in potential economic losses. Meanwhile, a large heat storage and released rate cannot be achieved for the water tank with the limited size under the low temperature operation conditions. Compared with sensible heat thermal energy storage, the latent heat thermal energy storage (LHTES) is advantaged by its use of phase-change materials (PCMs) with high energy storage density at a near-constant phase-change temperature. To enable an energy efficient low temperature DH system, an appropriate storage medium with great thermophysical properties and low cost will be selected. The technical viability and practical applicability of the entire heating system will be experimentally and numerically investigated. A hybrid agent-based model predictive control (MPC) framework will be further built as a promising solution to achieve an effective energy management for the low temperature DH combined LHTES system. It is projected that the energy and economic performance of the DH combined LHTES system could be guided by the agent-based MPC. The capability of the agent-based MPC for performance e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Engagement of Citizens Into Renovation Decision Processes Using Social Science, Building Simulation and Participatory Advisory Tools', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

To meet the EU’s ambitious climate and energy efficiency goals, the rate of deep building renovations must increase by an order of magnitude. However, insufficient accessible information and unclear cost-benefit insights discourage homeowners from taking action. Moreover, decision-making varies widely depending on whether renovations are undertaken by individual families, multi-family co-owners, or entire neighborhoods. The RenoVisor project supports the acceleration of decarbonizing Europe’s building stock by empowering these 3 target groups to make informed, participatory decisions about building renovations and switching to green energy. It does so through 3 innovative digital tools that combine advanced building simulations, behavior modeling, and participative advisory tools. These tools overcome key barriers—such as financing challenges, the disruption factor, and decision-making complexity—by providing tailored renovation plans that integrate technical, economic and social aspects. For co-owned buildings consensus-building features help the owners to reach an agreement. Special emphasis is placed on addressing energy and transport poverty, ensuring that vulnerable households can access renovation pathways that enhance energy efficiency and mobility without compromising affordability. Piloted in over 10 000 households across Spain, Ireland, and the Netherlands, the user-friendly interfaces will encourage exploration and personalization of solutions, while a sales funnel–inspired design guides users toward positive renovation decisions, increasing the conversion from awareness to action.By offering multi-stage renovation planning and clear visualization of the increased climate change resilience as well as ecological and financial benefits of renovation measures, R
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'An innovative ECO inteRnal coverIng for metal and plastic conVEntionalS conTainers' (ECO-RIVEST), addressing dissemination and exploitation.

assistant: **Impact**

Paint buckets containing leftover paints present an important economic and environmental challenge in Europe. As is known, the containers that are used for paints must be subjected to separate disposal because of the inevitably traces of the potentially hazardous liquid product that was originally contained remain inside them. While they are commonly made of material that could in theory be 100% recyclable, empty and almost empty paint buckets in such a current stream of waste treatment end up either landfilled, incinerated or separated out and disposed of as hazardous waste generating unnecessary large amount of waste at a considerable higher cost and obvious additional stress for the environment. Each year, approximatively 900,000 tonnes of leftover paint are wasted in containers and only few of them (less than 5%) are currently being recycled. With 12% of the environmental burden caused by paint and about €1 billion spent with regard to their disposal, there is growing need today to find more environmentally friendly and cost effective alternative to such current paint container waste treatment solution.In this course of action, we present Eco-RIVEST, an innovative paint container bag covering solution devised to reduce up to 85% of leftover ""hazardous waste"" from paint containers. Consisting of a covering system provided to cover the inner surface of a container with plastic bag that would be removed and disposed once the product is finished, Eco-RIVEST not only maintains the product quality intact, but also greatly minimize the amount of waste generated by paint containers.  For our company, leader in the manufacturing of paint bucket solutions, we expect from Eco-RIVEST commercialization to provide us an important grow with an accumulated turnover of €7.14 milli
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Ecophysics of spore preservation resistance and injury typing (esprit-unilever)' under Fifth Framework.

assistant: **Concept**

Research into bacterial spore resistance for milder food processing whilst maintaining microbial safety and stability. Tool development to deter the preservation resistance and injury of bacterial spores using ecophysiology, advanced structural techniques and molecular biology.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Perceptual foundations of relational thinking' (ViSyRelPer) targeting Horizon Europe.

assistant: **Abstract**

Classic models of visual perception pose that the ultimate goal of vision is object recognition. Recentresearch suggests that visual perception is more sophisticated, representing the objects as well as therelations holding between them. Relational representations are a major research focus in cognitivescience, as they play a central role in human reasoning, language and social life. Yet, how they comeabout in the human mind/brain remains largely unknown. In ViSyRelPer, I study the role of the visualsystem in encoding relations, under the hypothesis that perception realizes the early stages of relationalrepresentation. I focus on two categories of relations: causal and social-interact. First, I use frequency-tagging electroencephalography (FTEEG) to measure the automatic neural response of the visual systemto visual stimulation, and study whether: a) such response is evoked during observation of relationalevents (e.g. for causal relation: collision events) and b) generalizes to different instantiations of the samerelation (e.g. for causal relation: launching and pulling events). Generalization would imply that the visualresponse reflects the representation of a relation, above and beyond the specific objects involved.Second, I use transcranial magnetic stimulation to interfere with activity in visuoperceptual brain areaswhile participants perform judgments on relational events. This study proves a causal role of visual areasin relation processing, thus substantiating the hypothesis of relation perception. Third, I use the aboveFTEEG approach to study perception of social and causal relations in individuals with autism spectrumdisorder. I will investigate whether alterations in the visuoperceptual stages of relation representationcould be a marker of difficulties in the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Photoelectrochemical CO2 Reduction Enhanced by Device Integration and Computational Techniques' to be submitted under Horizon Europe.

assistant: **Abstract**

Motivated by the adverse environmental and societal effects of fossil resources (global warming, pollution, loss of habitat due to mining, health issues), efforts to defossilize the energy, mobility and chemical industries have sought alternatives based on, among others, solar power. Solar-to-X technologies have therefore emerged as promising, since they integrate the energy and chemical conversion steps within a single device, thereby being in principle able to reach high efficiencies, while also having the potential to be deployed in a decentralized manner. Yet, developing such technologies and designing pertinent devices is challenging due to the complex, multiscale nature of the phenomena underpinning their function. Thus motivated, PREDICT aims to elucidate fundamental mechanisms underlying the performance of photo(electro)chemical (PEC) CO2 reduction devices using advanced computational materials science and multiscale modeling techniques. By advancing quantum chemistry approaches for calculating excited state structures and dynamics, as well as bridging electronic, atomistic, mesoscopic, and macroscopic scales, this project will deliver a transferable theoretical and computational framework for the simulation of PEC devices, such as artificial leaves and beyond. The PREDICT modeling framework will be demonstrated via theoretical explorations of novel materials and processes for PEC CO2 reduction, enabling the fundamental understanding of phenomena crucial to the performance of PEC devices, and providing guidelines for optimizing the design to achieve superior performance. The framework and models will be further validated through collaborations with successful experimental projects from Area 1 of the call. Expected outcomes encompass improved device architectures