RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Exploiting the Tumor Proteome Activity Status for Future Cancer Therapies' to be submitted under Horizon 2020.

assistant: **Abstract**

Kinases are key regulators of protein activity and phosphorylate thousands of proteins in cells. The phosphoproteome can hence be viewed as a proxy for the proteome activity status of a cell. Dysregulation of the phosphoproteome can cause diseases such as cancer. As a result, kinase inhibitors have become important drugs in oncology and nearly 50 are approved for use in humans. As they typically have a range of targets, there is enormous potential for repurposing these drugs for other cancer entities. To implement this in the clinic, it is important to better understand: i) how the phosphoproteome of an individual tumor can be functionally interpreted, ii) how and to what extent kinase inhibitors modulate the phosphoproteome and iii) which drug is the best fit for modulating the proteome activity status of a particular tumor. This information is only partially or not available from classical cancer diagnostics or genomics. Therefore, the central aim of this project is to show that ground breaking new information for the diagnosis and treatment of cancer patients will come from measuring their tumor proteome activity status (TOPAS) by quantitative mass spectrometry. To this end, the first objective is to show that modulating the TOPAS of cancer model systems by kinase inhibitors functionalizes the phosphoproteome and reveals the cellular mechanisms of action of these important medicines. The second objective is to develop and validate diagnostic drug-, protein- and pathway-centric TOPAS scores able to make treatment suggestions based on the phosphoproteomes of cancer models and tumor tissues. The third objective is to demonstrate, on the example of sarcoma patients, that TOPAS scoring adds value to decision making by molecular tumor boards. Combining the strengths of pro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Developing 2-photon optical imaging for neural-network studies in medial entorhinal cortex of freely moving mice' (ANAT-MEC).

assistant: **Concept**

The medial entorhinal cortex (MEC) and the adjacent pre- and parasubiculum are thought to create an internal map of self-position that animals may use for goal-directed navigation.  This map uses a set of functionally specific and largely non-overlapping cell types: grid cells, border cells, speed cells, object-vector cells, and head-direction cells. The presence of multiple distinct functional cell types, matched in specificity only by cell populations in some of the sensory and motor cortices, allows us to examine input-output transformations and computational algorithms in association cortices with unprecedented power and detail. In order to examine these algorithms, however, an obvious and crucial first step is to map the division of function across cells in anatomical space. This requires recording of hundreds of cells at the same time in freely-behaving animals exploring open spatial environments. Unfortunately the absence of appropriate methods for neural recording at the population level has so far prevented a clear understanding of the broader organization of multi-cell-type and multi-layer networks of MEC, at both micro and macro scales.  　　        During my PhD, I invented a technique called “fast high-resolution miniaturized two-photon microscopy (FHIRM-TPM)”, which, through the use of a portable light-weight (2g) two-photon microscope, allows animals to move freely while large scale, single-cell-resolution calcium imaging is performed. In ANAT-MEC, I will refine this optical imaging method to study neural activity during spatial navigation in two-dimensional environments. I shall characterize in detail the anatomical organization of distinct cell types in MEC while mice engage in naturalistic, exploratory behavior in open spaces. Besides shedding light on t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Development of a sustainable and cost effective ballast water treatment technology with reverse pulsed DC electric field that excludes formation of oxidising free radicals', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The objective of the proposed project is development of a ballast water treatment system by using a pulsed DC electrical field for microbial inactivation of invasive species in ballast water. The EcoSeaSafe applies an electrical designed pulse shape with instant reversation of the current direction, which generates a reversed electric field that prevents a secondary reaction of radicals which change the water chemistry while fully eliminating target species specified by the gudelines of International Maritime Organisation (IMO). Transfer of invasive marine species by ballast water is a major global ecological and economic problem. As a result, IMO has adopted a convention that requires proper management of ballast water that all ships must comply with progressively staring in 2009. There are, however very few treatment systems that have obtained IMO approval in spite of efforts being done a number of technology developers and vendors. With huge global market for new ballast water treatment technologies, the proposers of EcoSeaSafe have identified a new and big market opportunity that can enable them exploit a superior technology and enhance their competitive position and economic growth as well as international network of cooperation. The EcoSeaSafe system is a cost effective, environmentally accepted, user friendly, compact and safe technology. It has minimal footprint and can be easily installed on new ships and retrofitted on existing vessels without disrupting the structural integrity of the vessel. To attain the technological objectives of the proposed project, innovative developments will be undertaken that include development of innovative pulse generator, a novel radical reactor of innovative alloys and a process control unit for controlling the required pulse f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'A new boost for green jobs, growth and sustainability'.

assistant: **Objectives**

Moving to a greener economy creates the need for new skills and competencies profiles, requiring the development of strong alliances for the adjustment of current training and qualification frameworks. On the basis of a Quadruple Helix approach, this project aims to define and develop a training and accreditation scheme on green skills. This scheme will address, in an articulated way, professional, market and customer barriers that stand in the way for the consolidation of Energy Efficiency (EE), Renewable Energy Systems (RES) and nearly Zero Energy Buildings (nZEB). It will be based on on-site and on-line training, transversally incorporating BIM and LEAN methodology. Specifically, the project will:*Improve skills of workers from the construction industry on EE, RES and nZEB, taking into account the entire value chain of the building.*Promote cooperation and understanding between the different trades and professional groups by incorporating to the training the quality paradigm known as LEAN Construction as well as BIM methodology.*Develop a new standard of sectoral competencies on EE, RES and nZEB following the methodology EQF (learning outcome approach) as well as ECVET and quality criteria EQUAVET.*Develop a new ""Energy Audit"" qualification.*Foster the specialization of SMEs in sustainable construction and its leadership in the market, allowing knowledge to be translated into innovative services to gain market share.*Certify skills by creating the accreditation ""Green tag"" to promote interaction and collaboration between stakeholders throughout mutual recognition.*Encourage innovation and improvement of work processes in regard to customer relations, workers and SMEs (guidance, needs detection and decision making on health, comfort and EE).""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Prevention, mitigation, management of infectious diseases on cruise ships and passenger ferries' (2021-2027).

assistant: **Concept**

With vast experience, in-depth knowledge and established expertise in infectious disease prevention and control on passenger ships, HEALTHY SAILING consortium presents a comprehensive approach introducing innovative, multi-layered, risk and evidence-based, cost-effective tested measures for infectious diseases prevention, mitigation and management (PMM) differentiated for large ferries, cruise ships and expedition vessels. This approach covers: a) preparedness and response to known infectious diseases frequently occurring on passenger ships, diseases that have never occurred but for which preparedness is essential, diseases of unknown aetiology to ensure preparedness for future emerging pathogens/pandemics; b) the entire passenger/crew journey travelling from home to ship and returning, on-board, during shore-side visits; c) ship-board operations, shore-side company operations, port destinations and communities; d) a global perspective of project outputs towards communities and passenger shipping industry. Epidemiological studies, risk assessment, modelling for disease spread and aerosol/droplet dispersion and setting disease thresholds/alert levels will develop a scientific evidence-base and support production of evidence-informed guidelines on COVID-19 for ships/ports, passengers/crew vaccination, ventilation systems and expedition vessels’ medical operation needs. Development/testing of ship-specific syndromic surveillance, AI systems, decision support tools will contribute to early health threat detection on-board, risk-based proportionate responses, and healthy on-board environments.  Toolkits for blended learning with hands-on training and technology induced behaviour change will further knowledge, awareness and compliance of all stakeholders. An integrated e-pass
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Socio-environmental trade-offs and synergies in terrestrial carbon-water coupling in a changing Planet'.

assistant: **Innovation**

Terrestrial carbon and water cycles are strongly coupled. Rising atmospheric CO2 and climate change have accelerated terrestrial water cycle, causing reduced soil moisture, and more frequent and severe droughts. Such environmental changes have modified vegetation functions, endangering the stability of terrestrial carbon budget. Human activities, such as deforestation and intensive water use, have further influenced carbon-water coupling by exacerbating external perturbations. A weakening of the terrestrial carbon sink induced by progressive water stress conditions could further destabilize the climate system with potential dramatic consequences for human societies.Despite its importance, the sensitivities of terrestrial carbon-water dynamics to socio-environmental changes remain elusive. The complexity of the topic, its interdisciplinarity, together with knowledge and methodological gaps in observing, understanding, and predicting carbon-water coupling, have hampered so far substantial progresses.TYPIC aims to respond to such emerging global challenge by addressing two key questions: How does terrestrial carbon-water coupling respond to socio-environmental changes? How have socio-environmental trade-offs and synergies influenced the trajectories of terrestrial carbon-water dynamics over the last decades?Here, I propose to investigate the subject with a novel approach that builds on the integration of Earth observations with big-data technologies. Satellite retrievals will be used in combination with advanced statistical tools to quantify spatial and temporal variations in terrestrial carbon-water coupling at the global scale. The underlying socio-environmental mechanisms will be disentangled through causal inference methods. Hotspot areas subject to amplification or co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Ampher Controller Technology' (ACT).

assistant: **Concept**

Uptake of electric vehicles (EVs) depends on the availability of charging points. If charging the EVs is not possible, people will stop buying them. In some regions, the available grid capacity is already setting limits to how many EVs can be charged simultaneously.Current charging station controller technologies do not enable using the full available grid capacity. As much as 2/3 of it may remain unused. With such technologies, the only solution to grid congestion is to increase grid capacity, but this would cost billions and take decades.Ampher unique controller technology enables using the full available grid capacity and allows charging up to 6x more EVs simultaneously with the same grid connection than current technologies. This is achieved with breakthrough microcontroller and semiconductor technologies, instead of high investments into infrastructure.With Ampher controller, all EV charging stations can be made smart and European climate goals can be achieved.


**Keywords:** Power electronics,Smart grid,Smart controller technology,EV charging technology
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Archaeology on the Edge: Northern Europe and the Circumpolar World' (ArchSci2020), addressing dissemination and exploitation.

assistant: **Impact**

ArchSci2020 will provide structured state-of-the-art doctoral training to the next generation of archaeologists and biomolecular scientists forging a new generation of biomolecular archaeologists. Few other academic disciplines have been so transformed in the last decade as Archaeology. ArchSci2020 meet the need of a new generation of researchers. International, intersectoral and interdisciplinary training will equip its early-stage researchers (ESRs) with specific research-related and transferable skills, in order to provide enhanced career prospects across academia, industry and the third sector. The proposed ArchSci2020 network will bring together four leading research clusters each with complementary expertise to deliver an integrated, flexible training package that will provide a sound basis for academic independence and preparation for vocations in the archaeology, heritage and beyond. ArchSci2020 will combine (i) a common purpose, (ii) an unconditional commitment to the student experience, (iii) a pro-active stance towards international, inter-institutional research support and interdisciplinary study, (iv) a simple but effective management structure provided by a Management Team, Supervisory Committee and the Work Package leaders, (v) and an established academic infrastructure and reputation.Key features of ArchSci2020:1. ArchSci2020 will create a multidisciplinary training environment that brings together archaeologists, biologists, mathematicians, analytical chemists, and policy experts around an archaeological hub.2. ArchSci2020 priorities and cross-cutting training themes align closely with ‘Grand Challenges’ across its themes of Health, Diet, and Environment and incorporates the important current skills and future training needs in archaeological science. 3
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Combined dry removal of particles and gaseous compounds from biomass combustion off-gases in a filtration-type particle separator' (1994-1998).

assistant: **Concept**

PROJECT OBJECTIVES Principal objective is the definition of process parameters and operating limits for a model dry gas cleaning system, in which stable and economical particle filtration cycles as well as a reduction in content of HCI, SO2, NOx, certain volatile organic species (VOC) and certain metals in particulate form by simultaneous addition of sorbents and/or catalysts into the gas stream can be achieved. Important objectives are the use of existing rigid ceramic filter material at regeneration pressures below 10 bar and temperatures below 600 C; emission targets for particles and HCI are 10 mg/m3, for SO2 50 mg/m3 and for NOX 200 mg/m3. TECHNICAL APPROACH A dry gas cleaning system for combined removal of particles and gaseous contaminants on the basis of VDI Guideline 3926, having a flow rate of 6 Nm3/h at max. 600 C will be designed, built and tested. It will then be used to establish filtration cycles for redispersed fly ash from biomass combustion during concomitant sorbent dosage to remove defined amounts of components. The particulate phase will be generated by dry dispersion of ashes; the gaseous components will be added by injection of defined amounts of HCI, SO2 and NOX. Particulate removal will be based on ceramic filter elements. Vapor phase removal processes will be based on absorption or adsorption technology using NaHCO3, Ca(OH)2 or activated charcoal. Additional filtration cycle data related to the influence of water vapor will be obtained on an existing filter unit using rigid ceramic candies of 1.5m length. That unit will be modified for these tests. Additional data will be obtained to characterise the particulate and gas phases. During the third project year, tests will be run with clean and contaminated biomass at up to 250 kg/h on an experimen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Digitally empowering citizens to deliver the twin transition' under Horizon Europe.

assistant: **Concept**

The energy transition of homes toward the EU decarbonisation targets involves many options and choices, the average citizens cannot navigate this maze and identify the best solutions for them. Professionals providing relevant services encounter substantial costs in tailoring their services to individual potential customers due to unavailability of essential data from actual households. DECODIT will develop digital services to support citizens on decision making for participated in the energy transition through co-created services and customer journeys. DECODIT will deliver tools that clearly present concrete, personalised & comparable propositions to citizens for future-proofing their homes based on federated, data-driven services from multiple, diverse service providers. Thus, citizens will be able to compare and select the options that best fit their specific situation and personal needs via apps supporting natural language interfaces, so that citizens with low energy or digital literacy can benefit. Also, DECODIT will facilitate financing for the selected interventions through cross-sector, data-driven loan underwriting approaches to reduce entry barriers for capital providers, hence unlocking consumer investment in home upgrades. DECODIT will contribute in shaping the smart energy landscape with critical enablers, such as enabling business models and market & regulatory conditions. Project results will be demonstrated in four European countries (Latvia, Spain, Greece, Switzerland) that are very diverse in terms of building characteristics, cultural and regulatory frameworks, climate conditions, economic capabilities, etc. Piloting activities will be held under the supervision of market actors that span the value chain needed for exploitation (energy suppliers, ESCO,