RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'deVEloping scientific Research with ethIcs and inTegritY' in the context of a Horizon Europe call.

assistant: **Objectives**

Different ""machines of trust"" in science have been identified in the literature: research ethics, research integrity, science communication, benefit sharing and technology assessment. Previous EU funded projects have focused on particular actors of the trust in science ecosystem (e.g. scientists, research funding organisations, research ethics committees) to explore the impact of particular ""machines"" (e.g. science communication, research ethics). VERITY goes beyond the state of the art by conceptualising ""stewards of trust"" as the actors of the ecosystem that are responsible for upholding societal trust in science and facilitating science-society co-creation, either this refers to formally responsible organisations like research funding organisations and higher education institutions, or it refers to de facto responsible organisations like social media companies and video streaming platforms which influence societal perceptions of science and innovation. VERITY combines multidisciplinary expertise, both from the social sciences and engineering, to synthesise existing knowledge to evaluate tools and methods for enhancing trust in science through original research and small-scale participatory activities, before producing the VERITY Protocol of Recommendations for ""stewards of trust"". VERITY brings forward interdisciplinary expertise to perform network analysis and execute interventions on social media, to validate the VERITY Protocol and alleviate practical barriers for its uptake in practice by different stakeholders. VERITY findings will be widely disseminated to different ""stewards of trust"", such as policymakers,  research funding and performing organisations, higher education institutions and other research and innovation actors, to enhance societal trust
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Trans-Atlantic Modelling and Simulation For Cyber-Physical Systems' (TAMS4CPS).

assistant: **Concept**

Smart systems, in which sophisticated software/hardware is embedded in physical systems are part of everyday life.  From simple products with embedded decision making software to massive systems in which hundreds of systems, each with hundreds or thousands of embedded processors, interoperate, the growth of cyber-physical systems (CPS) is likely to accelerate.  For Europe to benefit from this expansion, while avoiding the pitfalls that such complexity creates, there must be advances in the modelling and simulation (M&S) of CPS.  Collaborative research with the US will be an opportunity to advance European M&S capabilities for CPS.  The overall aim of TAMS4CPS is to lay the foundations for concrete EU-US collaboration in modelling and simulation for cyber-physical systems. To achieve this, Loughborough and Newcastle Universities (M&S) will work with Steinbeis Innovation (road mapping) and leading researchers in the field at top US universities to create:- A strategic research and collaboration agenda, endorsed by researchers in EU and US- A set of test cases for model developers to perform collaborative evaluation- A state of the art web-based report to act as a baseline for collaborative researchTaking a consultative approach, we will engage industry and academic researchers and M&S users in workshops and web-based meetings to prioritise M&S research challenges and to create a constituency of future collaboration partners for pre-competitive research in the Artemis themes, of:- Architectures principles and models for safe secure Cyber-Physical Systems- Systems design, modelling and virtual engineering for Cyber-Physical Systems- Autonomous adaptive and cooperative of Cyber-Physical Systems- Computing platforms and energy management for Cyber-Physical SystemsTo which is
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Nanoscience doctoral training to address societal challenges in materials science, biomedicine and energy'.

assistant: **Innovation**

Nanotechnology is widely considered to be one of the drivers of innovations in the 21st century. Specifically, nanoscience strongly contributes to several of the key enabling technologies identified by the European Commission, including Nanotechnologies, Advanced Materials and Biotechnologies, and Sustainable development. In this way, nanotechnology also has significant potential to directly address Europe’s Societal Challenges, including clean and efficient energy, resource efficiency, health and well-being. The effective use of nanotechnology requires a highly trained workforce able to tackle interdisciplinary challenges through combination of unique approaches, advanced materials and characterization techniques coupled with a clear understanding of technology and market needs. The GenerationNano program will effectively consolidate and leverage externally (public and private) funded projects to facilitate a cohesive training program that integrates multiple disciplines, mobility, training in innovation processes and leadership to produce tomorrow’s leaders in nanotechnology and nano-innovation. GenerationNano’s is highly timely and is specifically designed for the Lund region in Southern Scandinavia. First, large investments into basic nanoscience have by now built up an extensive base of knowledge, infrastructure and materials synthesis capabilities related to nanostructures, and a large number of highly innovative applications are emerging. The time to focus on future applications is now. Second, the project is perfectly timed to coincide with major investments into regional nanotechnology e.g. world-leading nanomaterials research at NanoLund (the host of GenerationNano); the worlds brightest synchrotron MAX IV; ; the start of institute- and pilotfabrication operat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Pan-European infrastructure for management of marine and ocean geological and geophysical data' under Seventh Framework.

assistant: **Concept**

The overall objective of the Geo-Seas project is to effect a major and significant improvement in the overview and access to marine geological and geophysical data and data-products from national geological surveys and research institutes in Europe by upgrading and interconnecting their present infrastructures.The Geo-Seas partnership has taken a strategic decision to adopt the SeaDataNet interoperability principles, architecture and components wherever possible. This approach allows the Geo-Seas upgrading to gain instant traction and momentum whilst avoiding wasteful duplicative effort. It is envisaged that the SeaDataNet infrastructure will provide a core platform that will be adaptively tuned in order to cater for the specific requirements of the geological and geophysical domains. A range of additional activities for developing and providing new products and services is also undertaken in order to fulfill the diverse needs of end-user communities.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Dissecting dynamic monoaminergic nervous system in C. elegans with genetically-encoded neuron activator protein channelrhodopsin-2.' (YTANIZAWA) targeting Seventh Framework.

assistant: **Abstract**

Biogenic monoamines are relevant to influential psychological diseases and brain plasicity. Knowledge obtained so far is however not enough for both of scientific and medical purposes. One obstacle against proceeding is the difficulty to find novel genes in genetically-inaccessible system like human brain. Another problem is the complexity of brain making it difficult to link cellular phenomena to behavior, which is necessary to understand brain.  To solve these problems, a genetically-accessible model organism C. elegans was introduced. With only 302 neurons, nervous system of C. elegans still has many properties common to the higher animal’s brain, including usage of monoamines and their roles in neural plasticity. Studies so far in C. elegans have provided much information by using mutants, exogenous amine application and neuron ablation. However, these methods have not considered dynamic property of aminergic system.  Here, the applicant uses the genetically-encoded light-gated cation channel channelrhodopsin-2 (ChR2). Because the body of C. elegans is transparent, by expressing and light-activating ChR2 specifically in aminergic neurons, one can examine the amine effectss on behavior with precise time resolution. The automated behavior quantification system makes it possible to identify any subtle behavioral changes caused by aminergic activation. The applicant will also examine the amine effects in cellular level, by live-imaging of downstream neuron activity with sensor protein cameleon. After identifying the amine effects, the applicant will start to dissect aminergic system with powerful genetics of C. elegans, which will provide a good starting point for further studies in future. This project for the first time allows us to examine the dynamic aspects of gene
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Ancient ConstructionTECHniques between East and West. Building traditions, technological innovations and workmanship circulation: from Roman Arabia to Medieval Europe.' to be submitted under Horizon 2020.

assistant: **Abstract**

This proposal is designed to study the circulation of ancient construction knowledge in the Mediterranean through an innovative and multidisciplinary approach to the analysis of built heritage. Particular attention will be given to the study of a specific construction technique, the arch, and how it influenced the types and techniques of architectural construction between the 2nd and 8th centuries AD, starting in the territories of the Southern Hawrān (nowadays Jordan and Syria), where the Hellenistic-Nabataean, Roman-Byzantine, Parthian-Sasanian and early Islamic architectural cultures met and influenced each other. In this fertile basin of local experiences, new building techniques and architectural typologies developed and from there spread throughout the Mediterranean basin. The transdisciplinary approach of the project will also allow an in-depth and innovative study of the phenomena behind the ancient construction processes, in terms of relationships between commissioners and workers, workforce and the specific construction techniques employed. The application of new digital technologies will be fundamental for the success of the project; in particular, a web-based GIS will be implemented to record the vertical surfaces, and an operational protocol for three-dimensional architectural survey will be developed, via which photographic-quality virtual reconstructions of built heritage will be generated by integrating digital photogrammetry and laser scanner. New technologies will also play a fundamental role in the presentation and diffusion of the data thanks to a fully open-access philosophy in which the results will be made available not only to the scientific community but also to the general public. Conceived as such, the project will be fundamental for both the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Peptidergic Neuromodulation of Sensory Representation in the Brain' to be submitted under Horizon 2020.

assistant: **Abstract**

Animals interact with and respond to their environment by processing sensory inputs such as visual and auditory cues, touch, taste and smell. How an animal responds to sensory inputs however depends on its internal state (e.g. sleep, wakefulness, stress, fed or starved conditions), such that the same sensory input can produce different behaviours. Neuromodulators play an important role in mediating the internal state of the animal. Neuropeptide Y (NPY) and Gonadotropin-releasing hormone (GnRH) are neuropeptides that are conserved across vertebrates and modulate feeding and reproductive behaviours, antagonistically. They are produced by discrete neuronal populations, and are dispersed widely throughout the brain. Studies suggest that both GnRH/NPY modulate the basal olfactory response by altering the synaptic properties of olfactory receptor neurons. However, it is not known how GnRH/NPY influence the processing of chemosensory information in the olfactory bulb (OB) and ultimately odour driven behaviour. Here, I will use an optically transparent and genetically amenable vertebrate model, zebrafish to study brain function and behaviour. First, I will use genetic methods to specifically label, and visualise the activity of the GnRH/NPY neurons in response to natural odours ex vivo. Next, I will manipulate the activity of these neurons using optogenetics and by expressing neurotoxin/cell ablation genes, and study the effect on olfactory processing in the OB. Finally, after manipulating the activity of GnRH/NPY neurons, I will analyse the effect on odour driven behaviour. This will reveal the role of these neuromodulators in olfactory processing and hence on odour driven behaviour in vertebrates. This project unites my expertise in molecular genetics with that of my host in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Robust Explainable Controllable Standard for drug Screening', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

In 2021, drug development pipelines last 10 years in average, and cost around $2 billion, while facing high failure rates, as only around 10% of Phase 0 drug candidates reach the commercialization stage. These issues can be mitigated through drug repurposing, where existent compounds are systematically screened for new therapeutic indications. Collaborative filtering is a semi-supervised learning framework that leverages known drug-disease matchings to make novel recommendations. However, prior works cannot be leveraged because of their lack of focus on human oversight and robustness to biological data.This project aims at bridging the gap between drug research and collaborative filtering by implementing a RECeSS classifier, that is (1) Robust: deals with class imbalance in drug-disease matchings, and missing drug/disease features, by semi-supervised learning;(2) Explainable: connects predicted matchings to perturbed biological pathways through enrichment analyses, based on the learnt importance of features in the model;(3) Controllable: guarantees a bound on the false positive rate using an adaptive learning scheme;(4) Standard: algorithms are trained and tested by a standardized open-source pipeline.Predicted matchings will be independently validated by structure-based methods. This innovative interdisciplinary project relies on a solid basis of newly curated data (up to 1,386 drugs, 1,599 diseases, 12 feature types). It is primarily supervised by Pr. Olaf Wolkenhauer, at SBI Rostock, whose team has an expertise in drug repurposing, in systems biology and data imbalance in machine learning. This project will help the fellow develop new skills, and enhance her professional maturity in academia.In the short term, this would yield the first method that fully integrates b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Persistence of Verocytotoxigenic E. COLI 0157 in Aquatic Biofilms' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Research objectives and contentVTEC verocytotoxigenic E coli), in particular E cold 0157:H7, have been recognised as a major food borne pathogens, and have caused several large outbreaks of haemorrhagic colitis in the USA, Japan and the UK. There is no specific treatment for the disease. Consequently, VTEC infection represents a significant and serious public health problem associated with food processing work surfaces and inefficiently disinfected potable water supplies. Direct observations have clearly shown that biofilm bacteria predominate, numerically and metabolically in different plumbing material or food processing work surfaces causing a multitude of problems because of the relative inefficiency of classical disinfection treatments.The control and containment of E. I cold 0157 in safe maintenance of potable water supplied used for drinking, personal hygiene and I washing foodstuffs will be possible by studying the persistence of E. cold0157 in aquatic biofilms. The dispersion and survival of VTEC 0157 will be analysed by using a continuous-culture model of biofilm growing on a specific tile surface such as copper, galvanized iron, mild steel, stainless steel, bitumen-painted steel, or new materials such as polyethylene or PVC after classical disinfection treatments with chlorine and monochloramine at 5, 15 and 25rC. Detection of the pathogen, without disrupting the biofilm structure, will be performed by using a differential interference contrast (DIC) microscope after introducing a stable marker gene (Green Fluorescent Protein) into VTEC 0157. Metabolic state of cells embedded in the biofilm matrix will be analysed by using different fluorochromes such as cyanotetrazolium chloride (CTC) which allow characterisation of the respiratory activity of the cells. Suc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Exact results in quantum deformed holography' (DEFORMED-HOLOGRAPHY).

assistant: **Concept**

Integrable models --- of which the Kepler problem or the Heisenberg spin-chain are celebrated examples --- are the exactly solvable building blocks upon which the whole theoretical physics monument stands. While they describe a simplified version of nature, their tractable structure gives invaluable insight into complicated systems closer to the real world. Remarkably, they also lead to major advances in our understanding of quantum gravity and holography, an area in which the need for analytical tools is critical due to the lack of experiments. Integrable theories appear in instances of the AdS/CFT correspondence, a duality relating string theories on Anti-de-Sitter space-times to Conformal Field Theories living on the boundary of these space-times. The aim of this project is to explore extended versions of AdS/CFT holography through the study of integrable quantum deformations. The specific objectives are (O.1) to establish new connections between quantum deformations of superstrings, (O.2) to compute physical observables in these theories via adapted integrability techniques, (O.3) to explore the quantum properties of these deformations and (O.4) to constrain their dual theories. Constructing and studying new deformations of AdS/CFT has the potential to dramatically expand the scope of our understanding of string theory, quantum field theories at finite coupling and holography. Integrability is expected to provide a crucial guiding principle and invaluable tool in harnessing such a potential. Moreover, this project will connect mathematical and physical aspects of quantum group.


**Keywords:** Integrability, AdS, CFT, Quantum deformations