RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Sustainable European Advanced Subsea Tidal Array', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

In the SEASTAR project, coordinator Nova Innovation (Nova) leads a world-class team to deliver a 4MW array of 16 tidal stream turbines at the EMEC Fall of Warness tidal site in Orkney - the worlds first large tidal farm, which will contain more tidal turbines than are currently deployed worldwide. SEASTAR will utilise Nova's well-proven M100D turbine, developed in partnership with project partner SKF - the worlds leading supplier of rotating equipment. The project builds on the success of Nova's six-turbine Shetland Tidal Array - the world's first offshore tidal array - which was delivered under the H2020 EnFAIT project by a team including SEASTAR partners SKF and Wood. They are joined in SEASTAR by DLA Piper, the leading global law firm in renewable energy, and by specialists in sustainability, insurance, consenting, communication, engineering and offshore operations. SEASTAR will demonstrate for the first time the industrial systems, manufacturing and operational techniques required to efficiently deliver a large tidal farm. It will generate and share transferable knowledge on key consenting risks, de-risking future large arrays globally. And it will improve the bankability of tidal energy by cutting costs, proving performance, and enhancing the insurability of large tidal farms. SEASTAR represents a step change for tidal energy. Volume industrial manufacturing, operation and maintenance techniques will be applied for the first time to the full lifecycle of a tidal farm, from design, procurement, production, shipping, marshalling, deployment, commissioning, operation and decommissioning. The 16-turbine farm provides unique opportunities to address critical environmental evidence gaps and develop the cost-effective, reliable monitoring solutions at scale required to ac
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Biodegradable and Eco-friendly Smart Hydrogels for the Sustained Intraperitoneal Release of Chemotherapeutics as a Novel Local Therapy Approach for Advanced Ovarian Cancer' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Ovarian Cancer (OC) is usually diagnosed in advanced stages when metastasis into the intra-abdominal (i.a.) cavity already occurred. The OC standard-of-care efficacy is hampered by drugs high systemic toxicity and the early appearance of resistance. Thus, advanced OC remains an unmet clinical need, forcing the need for alternative therapies based on drugs local slow-release at the i.a. cavity. Hydrogels (HG) have been proposed as in situ drug sustained release systems in the biomedical field. Their application avoids off-target effects caused by drugs systemic administration and improves their therapeutic efficacy. Thermo-responsive HG (TR-HG) gained special attention due to their ability to be liquid at room temperature, enabling their injection, and jellify at body temperature.  Accordingly, the goal of HydroTheC is to provide a new on-demand TR-HG as a new delivery depot system for the impairment of OC i.a. spread. The innovative character of the proposed HG relies on: i) Use of Natural and eco-friendly components and synthesis methods recognized by Green Chemistry rules, ii) Use of in silico bioinformatic tools to reduce unnecessary expenses and environmental impact, iii) Nanoparticles incorporation to create e multicompartment HG system, and iv) On-demand character, due to its easy adaptability to any drug or clinical conditions that would benefit from local therapy. For the project success will be crucial the team interdisciplinary character, as well as the perfect match of knowledge existent between the candidate and associated institutions. In the end, it is expected to obtain a novel HG that will significantly increase the standard-of-care therapeutic window, increasing OC patients survival and quality-of-life. Moreover, the designed HG would serve as a technol
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The Balance between Transport and Mechanical Issues in 3D Regenerative Tissues, Using the Perfusion Bioreactor' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Difficulties encountered in tissue engineering invited the use of perfusion bioreactors to deliver essential nutrients to cells within tissue-engineered constructs. Despite the increased nutrient transport achieved, solute perfusion caused harmful mechanical stresses to the cells. Interestingly, some bioreactors are employed to mechanically stimulate cells, improving their biological functions. However, stresses associated with perfusion bioreactors are counterproductive. Currently, to address this issue, perfusion rate is lowered to minimise mechanical implications to the cells. Consequently, nutrient delivery is sacrificed. Therefore, this project aims to balance the nutritional advantage offered by perfusion, and its associate cell-death. By doing so, essential nutrients may be perfused to all regions of tissue-engineered constructs, at flow rates whose mechanical implications are harmless, or even encouraging to cells. To alleviate the costly and iterative experiments necessary to achieve these aims, the use of computational modelling will be central to the project, and incidentally, forms the training objective of the proposal. However, key findings will be corroborated with laboratory experiments.  Combining techniques associated with cell biology, material science, and mechanical engineering. The specific objectives of the proposed study are to: Model the fluid flow-induced deformation of cells within tissue-engineered constructs. Using fluorescent staining, corroborate relationship between fluid flow and cellular deformation. Design a system to mechanically deform cells without fluid flow. Investigate the influence of cellular deformation, with and without fluid flow to their viability and biological activities. Extrapolate the individual contributions of fluid
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Active actin-microtubule crosstalk in reconstituted systems'.

assistant: **Concept**

Living cells maintain a high degree of functional and structural organization which largely depends on a highly dynamic scaffold, the cytoskeleton, with microtubules (MTs) and actin filaments as the central elements. While both components are comparably well characterized individually, their interplay and mutual regulation remains poorly understood. Precisely their cooperative functioning, however, is increasingly regarded as a central element for many cellular key processes including cell division, cell migration, and adhesion.The central aim of this proposal is to achieve a more profound and quantitative understanding of actin-MT crosstalk using a simple yet realistic reconstituted model system. Centrosome nucleated microtubule asters will be embedded into passive and active actin networks. Coupling between the two cytoskeleton components will be introduced in form of transient binding of growing MT plus ends to actin filaments mediated by tip-tracking EB3 and MACF, a highly relevant actin-MT linker.I will study the mutual influence between a surrounding actin matrix and the dynamic MT asters. Addition of myosin motors will induce actin network contractions that should strongly affect MT growth dynamics. Applying computer-based image analysis routines will allow me to quantify centrosome motion and microtubule tip dynamics. Further, I will investigate the additional effects of cell size confinement on the spatial self-organization of actin and MT asters. Finally, I aim at mimicking the actin-MT crosstalk at the leading edge of migrating cells by establishing an actively treadmilling actin network growing against the aster-based microtubules of opposite polarity.The proposed work will be carried out at the AMOLF institute, simultaneously in the groups of Prof. M. Dogte
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Reassessing Ninth Century Philosophy. A Synchronic Approach to the Logical Traditions' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

This project aims at a better understanding of the philosophical richness of ninth century thought using the unprecedented and highly innovative method of the synchronic approach. The hypothesis directing this synchronic approach is that studying together in parallel the four main philosophical traditions of the century – i.e. Latin, Greek, Syriac and Arabic – will bring results that the traditional enquiry limited to one tradition alone can never reach. This implies pioneering a new methodology to overcome the compartmentalization of research which prevails nowadays. Using this method is only possible because the four conditions of applicability – comparable intellectual environment, common text corpus, similar methodological perspective, commensurable problems – are fulfilled. The ninth century, a time of cultural renewal in the Carolingian, Byzantine and Abbasid empires, possesses the remarkable characteristic – which ensures commensurability – that the same texts, namely the writings of Aristotelian logic (mainly Porphyry’s Isagoge and Aristotle’s Categories) were read and commented upon in Latin, Greek, Syriac and Arabic alike. Logic is fundamental to philosophical enquiry. The contested question is the human capacity to rationalise, analyse and describe the sensible reality, to understand the ontological structure of the world, and to define the types of entities which exist. The use of this unprecedented synchronic approach will allow us a deeper understanding of the positions, a clear identification of the a priori postulates of the philosophical debates, and a critical evaluation of the arguments used. It provides a unique opportunity to compare the different traditions and highlight the heritage which is common, to stress the specificities of each tradition wh
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Innovative Method and Procedure to Assess Counter-violent-radicalisation Techniques in Europe' under Seventh Framework.

assistant: **Concept**

IMPACT Europe will develop an evaluation toolkit to help professionals in the public and voluntary sectors design and implement an evaluation of their programmes tackling violent radicalisation, whether policies or interventions. The toolkit will also help professionals go beyond the evaluation of a single project by integrating promising practice into the design and implementation of future programmes.This evaluation toolkit will be composed of four elements:1) A standardised methodology, to provide professionals with a tool to conduct robust evaluations;2) An evaluation results database, to allow professionals to analyse these results over time, identify promising practice and develop a more informed understanding of violent radicalisation;3) A training course (including a train-the-trainer component), to build professionals’ capacity to design, carry out and learn from appropriate evaluations;4) A training manual, to provide easy reference for professionals applying the toolkit.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'The Memory of Solitons' in the context of a Horizon 2020 call.

assistant: **Objectives**

Quantum field theory (QFT) is undoubtedly one of the most important achievements of modern theoretical physics, with broad applications ranging from condensed matter systems to elementary particle physics. Despite its successes, the current formulation of QFT is incomplete and we lack tools to address from first principles a wide variety of interesting physical systems, including the dynamics of quarks within protons, phase transitions, and high temperature superconductors. The present project aims at addressing this issue by establishing a novel, powerful and unconventional paradigm for QFT without relying upon the existence of a perturbative expansion. The cornerstone for such a paradigm is the following remark: in a wide variety of simple examples it is possible to compute exactly the values of several observables relying solely upon the knowledge of the spectrum of solitons of the given QFT. I call this effect the memory of solitons. My goal is to establish a research group that will develop and exploit the memory of solitons to study non-perturbative aspects of QFTs. The proposed strategy to approach this problem is twofold. On the one hand I focus on the simplest QFTs to develop my intuition on concrete and explicit examples: my laboratory consists of theories having supersymmetry and/or conformal symmetry where a plethora of exact results are available in the literature. On the other I exploit geometric engineering techniques in string theory, which gives access to the non-perturbative spectrum of QFTs from a completely different angle that allows exact computations to be performed, providing new insights into the mathematical structure of the theories involved. The combination of these techniques is so powerful that I have already obtained a wide variety of resu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Philology as Science in 19th-Century Europe' (PhiSci) targeting Horizon Europe.

assistant: **Abstract**

Philology once defined what it meant to be scientific – and it may yet once again. Increasingly a broad array of scholars using digital methods cite the historical accomplishments of philology as a model for systematic study around unwieldy and heterogenous textual corpuses. Despite this renewed interest, there is still no systemic account for the huge range of activity and aegis, data and networks, that propelled philology to its status as a model or even the 'queen of science' in C19 Europe. In drawing on history of science, media studies, information studies and diverse textual methods, this project offers that holistic account of how and why philology as a 'science in the making' achieved such extraordinary success. It articulates the widely sought yet unachieved bridge that would permit rigorous interdisciplinary exchange between philology – its historical and contemporary iterations – and present-day endeavors in the fields of digital humanities, critical data studies, infrastructure studies and de/post-colonial studies. PhiSci takes philology seriously as a science and gives it the kind of treatment that has dominated history of science for the last generation. Pioneering a novel account of philology from the French Revolution to First World War, it pursues a central question: How did local ensembles of protocols, representation, instrumentation and cooperation consolidate into robust programs for the genesis of stable knowledge and knowledge communities? It gives special attention to heterogeneity and universality in key concepts and practices and to physical aspects like media and infrastructure: elements undervalued or rarely grasped in terms of their epistemic work for producing data, evidence and facts. PhiSci will thus explain how philology operated as a re
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Microfluidic Diffusion-based Chiral Resolution' (CRMS), addressing dissemination and exploitation.

assistant: **Impact**

Chirality is an essential property of nature, producing and regulating fundamental phenomena in living matter. Chiral compounds are widely used in medicine, clinical, pathological, and other fields. Different enantiomers of chiral molecules have significant differences in pharmacological activities, metabolic effects, toxicity, and even opposite effects. Since most chiral compounds exist in the racemic form, it is important to develop strategies for rapid and efficient separation and purification of chiral compounds to deal with inevitable future threats such as diseases and viruses. Although many techniques for chiral resolutions have been developed over the years, most of them are impeded by low efficiency and accuracy, high energy consumption, tedious preparation and operation and high cost. Therefore, I propose a project, CRMS “Chiral Resolution using Microfluidics and helical Supramolecular polymers” which aims to develop a simple diffusion-based strategy for chiral resolution by incorporating helical supramolecular polymers (HSPs). In this project, I will combine the ability of HSPs to recognize the handedness of chiral molecules through non-covalent interactions with the diffusion-based separation ability of microfluidics for the enantio-separation of chiral molecules. I chose microfluidics for chiral resolution because it is a cost-effective and energy-efficient technique that takes advantage of the natural flow properties of the fluids entering the flow reactor for diffusion-based separation. CRMS project will not only start a new area of research in the junction of supramolecular chirality and flow chemistry but also have applications in pharmaceutical and cosmetic industries for enantio-separation of chiral drugs/ingredients.


**Keywords:** Supramolecular po
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Anti-infectious immune effectors in marine invertebrates: characterization and application for disease control in aquaculture' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

As world aquaculture is facing economical losses due to infectious diseases, the project objectives are to provide new therapeutic agents and new approach for the control of diseases in mollusc and shrimp production. The approach deals with the isolation and the characterisation of antimicrobial molecules, irnmune non-specific effectors produced naturally by these invertebrates and to investigate their antimicrobial properties against a wide range of pathogens. The selected antimicrobial effectors will be then monitored on larvae for their potential beneficial and/or protective effect against infections. Moreover, the expression of anti microbial effectors encoding genes will be analysed at population level for evaluation of their use as genetics markers for increased non-specific response to diseases. Candidate molecules and genes, as well as new selection approach, will be supplied for further exploitation in aquaculture.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'TWin of Online Social Networks' (TWON) targeting Horizon Europe.

assistant: **Abstract**

Experts, scholars, and leading political decision-makers warn that Online Social Networks (OSNs) have transformed public debate in harmful ways. Personalization algorithms, it has been argued, create so-called filter bubbles and echo chambers where users’ opinions are reinforced, amplifying processes of opinion polarisation. Despite frequent calls for interventions to minimize such undesired effects, there is no agreed-upon method for estimating the effects of changing the parameters of the design of a social network service. Crucially, the complexity of such systems makes it hard to translate results of isolated experiments into an estimate of the overall effects. The TWON project will develop a novel empirical method for systematically researching the effects of design choices of mechanisms inside OSNs, by creating digital twins of social network sites, called TWONs. The TWON can then be used to study counterfactuals, such as: How would the effects look like, had the OSN been designed differently?In order to achieve that, the TWON project will combine empirical observations of existing OSNs, theory-informed simulations, and specific case studies. These form an iterative process, in which we will build and refine the TWON. If successful, this would be a major leap towards a better understanding of platform mechanics, both for the scientific community and for societal stakeholders. The TWON project will produce evidence-based recommendations for regulatory innovations regarding OSNs and enhance digital citizenship by participatory methods. This can reduce the detrimental effects on democratic debates when platforms are primarily optimized for economic gain. TWON enables OSN research in a controlled but naturalistic environment that would not be possible relying on for-p