RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Design of an interface ASIC for RISC systems using a VHDL based independent" environment"' under Fourth Framework.

assistant: **Concept**

- The adoption of an advanced design methodology with the use of VHDL and the design of an interface ASIC for the R4000 RISC family of IDT microprocessors. MLS plans to design this ASIC in collaboration with the Centre of Microelectronics of INTRACOM (CEM). CEM will provide the advanced design practice, the training of MLS engineers, the final Mentor Graphics platform environment and will do the final technology choice as well as supporting the implementation of the ASIC.- To strengthen MLS' position in the embedded control systems market and in the prototype development work.- To disseminate the results of this Application Experiment on a European-wide scale.This Application Experiment has as its main objectives the utilisation of VHDL, the use of an Independent" Environment and the adoption of an advanced design methodology in order to improve the standard of design practice currently used by MLS Firmware S.A (OrCAD & ViewLogic EDA Tools).The Application Experiment will focus on the design of an advanced interface ASIC for the R4000 RISC family of IDT microprocessors that is used in high-performance embedded control systems i.e. fast telecommunications switching, high-speed networking (ATM switches) etc. The product will be tested with advanced prototype testing methods. The ASIC design will be carried out by MLS engineers with the support of INTRACOM engineers to ensure that the end-user learns sufficiently to repeat the process in the future without support."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Harvesting Dynamic 3D Worlds from Commodity Sensor Clouds' to be submitted under Seventh Framework.

assistant: **Abstract**

The current acquisition pipeline for visual models of 3D worlds is based on a paradigm of planning a goal-oriented acquisition - sampling on site - processing. The digital model of an artifact (an object, a building, up to an entire city) is produced by planning a specific scanning campaign, carefully selecting the (often costly) acquisition devices, performing the on-site acquisition at the required resolution and then post-processing the acquired data to produce a beautified triangulated and textured model. However, in the future we will be faced with the ubiquitous availability of sensing devices that deliver different data streams that need to be processed and displayed in a new way, for example smartphones, commodity stereo cameras, cheap aerial data acquisition devices, etc.<br/>We therefore propose a radical paradigm change in acquisition and processing technology: instead of a goal-driven acquisition that determines the devices and sensors, we let the sensors and resulting available data determine the acquisition process. Data acquisition might become incidental to other tasks that devices/people to which sensors are attached carry out. A variety of challenging problems need to be solved to exploit this huge amount of data, including: dealing with continuous streams of time-dependent data, finding means of integrating data from different sensors and modalities, detecting changes in data sets to create 4D models, harvesting data to go beyond simple 3D geometry, and researching new paradigms for interactive inspection capabilities with 4D data sets. In this project, we envision solutions to these challenges, paving the way for affordable and innovative uses of information technology in an evolving world sampled by ubiquitous visual sensors.<br/>Our approach is hig
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Molecular mechanism of calcium entry in the immune system'.

assistant: **Innovation**

T-lymphocytes require calcium entry though the plasma membrane for their activation and function. Recently, several routes for calcium entry through the T cell plasma membrane after activation have been described. These include CRAC channels (Calcium Release of Activated Channels), TRP channels (Transient Receptor Potential) and inositol-1,4,5-trisphosphate receptors (IP3R). Herein we are proposing the emergence of a new fourth route for calcium entry, composed of Cav channels (also known as L-type voltage gated calcium channels) and their regulator scaffold protein AHNAK1 (AHNAK/Desmoyokin). In excitable cells, such as neurons or muscle cells, Cav calcium channels constitute the major route for calcium entry. We have previously published that both helper (CD4+) and killer (CD8+) T cells express high levels of Cav1 alpha1 subunits (alpha 1S, -1C, -1D and -1F) and AHNAK1 after their differentiation and require these molecules for calcium entry during an immune response.This proposal aims to study the molecular mechanism by which this pathway is induced and functions. My preliminary evidence suggest that Cav channel calcium currents are induced by TCR stimulation, not by voltage depolarization, as described in excitable cells. Further studies proposed here are required to study this phenomenon.In this proposal, we will describe the observations and open questions, which ultimately suggests the involvement of multiple consecutive routes for calcium entry into lymphocytes, one of which is apparently mediated by Cav channels and AHNAK1.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for '“Weathering and nutrient export from subglacial environments: A novel stable isotope approach”' in the context of a Horizon 2020 call.

assistant: **Objectives**

The Earth’s surface has been dominated by cycles of glacial advance for more than two million years. Processes occurring at the glacier bed exert a fundamental control on the release of bioavailable elements to rivers and oceans and the evolution of the Earth’s surface, hydrosphere and atmosphere. As global temperatures rise and ice-sheets retreat, it is critical to constrain the roles that subglacial weathering processes play in controlling global biogeochemical cycles. The overarching goal of this project is to investigate the redox conditions that control vital nutrient and elemental release through a study of glacial outflows from contrasting subglacial environments. I will achieve this goal using a novel multidisciplinary framework incorporating cutting-edge redox sensitive stable isotope proxies (Mo, Fe and Se isotopes) of iron and sulphur cycling and oxidation state  to unique glaciated regions.  Using a combination of archived samples and focused field campaigns I will study subglacial outflow environments that differ in bedrock geology, regional climate and type of individual glacier drainage basins (e.g. ice cap, ice sheet and alpine glacier) in order to evaluate the importance of these parameters in weathering processes and ultimately the release of bio-available elements from the sub-glacial environment to rivers and oceans. Key questions I am to answer are how is the release of bioavailable elements a function of the redox state of the subglacial environment? Which of the three key parameters plays the most significant role? To what extent is this reflected in the enrichments of elements in solid/liquid phases? and how does this affect biogeochemical cycling downstream and nutrient supply?
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Intelligent Fish feeding through Integration of ENabling technologies  and Circular principle' (2014-2020).

assistant: **Concept**

iFishIENCi will deliver breakthrough innovations supporting sustainable aquaculture, based on enabling technologies and circular principles, thereby providing the European aquaculture industry with the competitive advantage and growth stimulation needed to be a mover in revolutionizing global efficiency in fish production and meet society's needs for food from the ocean. This ambitious task will be achieved by providing to the market the  iFishIENCi Biology Online Steering System (iBOSS) that significantly improves production control and management for all fish aquaculture systems.  iBOSS will maximise feed utilisation through smart feeding, provide continuous monitoring of fish behaviour, health and welfare and reduce response times to aberrations.  iFishIENCi will target circular principles and zero waste by qualifying new and sustainable organic value chains for feeds, and valorisation of by-products. iFishIENCi´s innovations will provide important new assets to  the consortiums SMEs, fish-farmers, feed producers and technology providers in the aquaculture sector, leading to market growth and job creation. Assets will be maximized through a comprehensive sustainability assessment and engagements with the sector, regulators and consumers. 11 European companies (SMEs and larger companies) and 7 research & Innovation expert groups are joining effort to achieve this innovation leap towards the implementation of smart feeding and smart breeding into the fish farming industry.


**Keywords:** Fish feed, AI, IOT, fish nutrition, algae, LCA
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Apoptosis Modelling for Treatment Decisions in Colorectal Cancer' in the context of a Seventh Framework call.

assistant: **Objectives**

With the arrival of new colorectal cancer (CRC) therapeutics targeting specific cell signalling pathways, such as anti-EGFR therapy, personalised cancer treatment is at the door step of clinical practise. This progress in drug development contrasts strikingly with current clinical practice, where decision making depends largely on clinical factors such as tumour staging and age of patient, with the success of such treatments being largely unpredictable. 5-FU-based chemotherapy represents the main stay of CRC therapy. DNA damaging agents such as 5-FU and anti-EGFR therapy seek to induce tumour regression through induction of apoptosis or sensitization to apoptosis. Dysfunctional apoptosis is well recognized as a key contributing factor in chemotherapy resistance. The aim of the APODECIDE consortium is to develop systems medicine tools that predict treatment responses in CRC patients to 5-FU-based chemotherapy and anti-EGFR therapy, based on a systems analysis of apoptosis and EGFR signalling pathways. Based on previous clinical proof-of-concept studies that demonstrated the unique potential of such approaches in predicting tumour resistance, the APO-DECIDE consortium aims to deliver new clinical decision making tools that enable personalised medicine approaches and ‘smart’ clinical trials design in the future. The SMEs will benefit from the project through the development of systems-based combinatorial biomarkers adapted to formalin fixed paraffin-embedded material, the routine material used in clinical histopathology, hence providing a unique opportunity for marketing and exploitation. SMEs and their academic partners will also develop computational whole body models reflecting drug pharmacodynamics and pharmacokinetics in patient cohorts, providing a unique market nich
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Universal Failsafe IGBT Package for robust power transmission' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Through a mixture of applied research and development, the Uni-Pack project will deliver technologies to reduce the manufacturing costs and improve the performance of plastic packaged IGBT (Insulated gate bipolar transistor) modules, in particular those for use in Voltage Source Converters (VSC) for High Voltage Direct Current (HVDC) power transmission. VSC technology enables efficient access to renewable energy sources and economic connection to the electric utilities grid. Trade studies have identified target IGBT module performance parameters for the HVDC market sector and the need to address the influence of gate drive strategies on converter cell/ module performance. Tailoring of IGBT structures for on-state/ switching loss trade-off across each market sector will be demonstrated and applied to develop 4.5KV enhanced DMOS and /or trench IGBT die exhibiting optimum performance for HVDC transmission.Applied research into a high thermal performance low profile package, designed for low inductance and having fully bonded interconnects will deliver step improvements in performance / reliability and reduced manufacturing cost. An important characteristic of the package will be its capability to fail to short circuit, a feature which is highly beneficial in reducing the system costs.A VSC system is currently in the design stage using standard IGBT modules and this will be used as a benchmark to demonstrate and quantify the degree of success.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'In the search of non-authoritative education in Hungary. Metadiscourses, identities and strategies in students’ and teachers’ interactive practices in standard and alternative settings'.

assistant: **Objectives**

As previous studies have proved, a majority of teachers maintain authoritative practices in Hungarian classroom discourses. Instead of behaving as independent agents, students often play the role of a patient, paraphrasing textbook definitions and their teachers’ words. This condition of dependence is usually reflected in students’ narratives, and classroom observations confirm this impression.Has classroom interaction in Hungary become more democratic after the fall of communist dictatorship (1989)? Previous studies suggest that in the case of mainstream state schools, the answer is no. However, from the end of the 1980s, there was a period of the rise of experimental programs in Hungary. CLIL (Content and language integrated learning) programs became popular, but did not become part of the mainstream, since they regularly serve the goals of elite training. It is unfortunate, because – as P. A. Duff has argued –, CLIL practices may promote democratic principles. CLIL may be intertwined with more active student participation and symmetric interaction than standard teaching.Based on large corpora collected in standard (state mainstream) and alternative (CLIL and experimental) settings, recorded classroom discourses and interviews will be compared. The systematic CA and DA analysis of classroom discourse and teachers’ and students’ narratives on their school experiences will serve a better understanding of institutional language policies, speakers’ identities and roles of agency. These are the piers of the cultural and linguistic socialization in a school, and their analysis supports the preparation of pedagogical innovations.The host institution’s expertise in CLIL and FL studies is inevitable for a better understanding of Hungarian formal training, and the role of metal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Membrane-triggered actin polymerisation: molecular mechanisms and morphogenesis'.

assistant: **Objectives**

Changes in cell shape, movement and vesicle traffic all require remodelling of the actin cytoskeleton. While the actin filament remains chemically the same, the filaments are assembled differently for different functions, e.g. long, bundled, parallel filaments in filopodia and short meshworks in endocytosis. The membrane appears to function as an organising surface where proteins come together to form multiprotein complexes to generate distinct actin structures. The proposed research is aimed at understanding the roles contributed by the membrane and the identities of the signalling and effector proteins that form distinct actin structures. I have formulated in vitro reconstitution systems, using artificial membranes and extracts, that mimic the formation of two uses of actin: filopodia and endocytosis. I propose to use these reconstitution systems to identify proteins important for actin polymerisation during filopodia formation and endocytosis and then investigate their functions in vivo in Xenopus embryos. The first objective is to use biochemical fractionation to identify actin filament elongation factors to understand how filopodial length and rate of growth are regulated in cells during morphogenesis, with the ultimate goal of finding a minimal set of proteins that can make a filopodium. My second objective is to elucidate the molecular pathway that dictates how phosphoinositides and membrane curvature stimulate actin polymerisation during endocytosis, find how different actin regulators contribute to trafficking pathways in vivo, and the contribution of these endocytic pathways to early development. Solving the molecular basis of how the membrane-cytosol interface signals to actin polymerisation will reveal how changes in cellular organisation are orchestrated to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Inventive forecasting tools for adapting water quality management to a new climate' (2014-2020).

assistant: **Concept**

Long-term climate change, extreme events, and seasonal variations in weather have profound impacts on water quality of rivers, lakes, and reservoirs. This implies a pressing need for tools anticipating the impacts of these environmental changes, and enabling effective water management that safeguards the ecosystem goods and services freshwaters provide. The increasing availability of new meteorological data products and advances in modelling tools now mean that it is possible for the first time to produce reliable forecasts for lake and river water quality on a regional and global scale, an unexploited potential in the water sector. Water managers will therefore profit from the education of a new generation of interdisciplinary trained professionals able to bridge fields such as data science, climate, hydrology, and freshwater ecology, who at the same time develop the necessary skills to translate knowledge and technical novelties into products useful for managers, policy-makers, and the general public. The primary objective of inventWater is to organize a platform providing cutting edge cross disciplinary education of tomorrow's water experts. The core activity is the training program, focused on the development and real-world application of inventive water quality forecasting tools across a range of time-scales, to support fast and reliable decision making as well as long-term adaptation policies. inventWater will bring water quality forecasting to the forefront of the scientific disciplines supporting water managers and policy-makers to design measures for adaptation to a new climate. The composition of the network and the multidisciplinary of the PhD projects will make tools developed by inventWater fellows applicable to a wide range of pressing water quality issues