RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Exploring the Prokaryotic-Eukaryotic Conservation of Antiviral immunity: from bacterial immune systems to novel antiviral drugs' to be submitted under Horizon Europe.

assistant: **Abstract**

Bacteria have evolved multiple lines of defense against their viruses, bacteriophages. Such weapons include restriction modification and CRISPR systems that have greatly impacted biomedical research. Studies aimed at uncovering novel defense mechanisms describe an unsuspected diversity of anti-phage systems, spanning thousands of protein families.  Several of these anti-phage systems, such as prokaryotic viperins,  appear to be ancestors of major eukaryotic antiviral pathways. This striking conservation between eukaryotic and prokaryotic immunity leads me to two hypotheses on which the present proposal is based. First, I postulate that the organisation of antiviral immunity in eukaryotes as an immune system, i.e. an integrated network of various antiviral mechanisms, might be conserved in prokaryotes. This implies that each anti-phage system does not act in isolation, but is rather part of a whole, the bacterial immune system. To explore this hypothesis, I will characterise the distribution of known anti-phage systems encoded in prokaryotic genomes. I will subsequently explore the potential synergies and co-regulation existing between these systems. I thereby aim to build an integrated map of bacteria antiviral immunity. Second, I hypothesise that prokaryotes produce additional small anti-phage compounds, such as the viperin products, with a potential activity against eukaryotic viruses. To explore this idea, I will study the molecular mechanisms of the viperin family. I will then use genomics to predict novel chemical based anti-phage systems and follow up with their experimental characterizations. These projects could lead to the identification of novel antiviral molecules that could be further harnessed in the clinic.Overall, I expect this proposal to generate new kn
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Cost management system for greening electrical and electronic equipment (GREEEN)' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

The vision of grEEEn for the new millennium: European electronics manufacturers are world leaders in benefiting commercially from greening of Electrical and Electronic Equipment (EEE). This shall be made possible by implementation of the proposed Cost Management System (CMS) for developing eco-efficient EEE. The research focuses on a CMS method for the complete life cycle of EEE leading to a CMS software as well as the application to developing eco-efficient product prototypes. The workpackages with their results are: Requirement analysis, Standardised EU CMS method for greening EEE (draft, report), Cost Data Base report, data bank), CMS Software grEEEn (prototype), Case Studies (5 reports of eco-efficient product prototypes realised with grEEEn), Exploitation & dissemination of results, Final report.grEEEn Cost Management System consisting of:- grEEEn software tool (D6)- grEEEn database with data-quality checks, aggregation and anonymization (D2, D4);- grEEEn method and proposal for a European grEEEn standard (D1, D3);- 5 case studies leading to grEEEn product prototypes/ services (D5).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Development of gamma-TiAl forgings in a low-cost near conventional hot-die process and process evaluation' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The strong need for higher efficiency, reduced CO2 emissions and weight reduction in aircraft engines leads to a demand of innovative light-weight high-temperature resistant materials which can partly substitute the materials currently employed. Presently, Ni-base alloys are used for turbine blades in aero-engines which satisfy the high mechanical and thermal requirements. A disadvantage of Ni-base alloys, however, is their high density of about 8 g/cm3. Intermetallic titanium aluminides, which exhibit a low density of about 4 g/cm3, are certainly among the most promising candidates to meet the required thermal and mechanical specifications. During the last decade several “wrought” gamma-TiAl alloys have been developed. These alloys exhibit excellent mechanical properties, but show a narrow processing window.Böhler Schmiedetechnik GmbH & Co KG (BSTG) is specialized on forging processes of materials like Ni-base and Ti-alloys for aero engine applications with a high demand on structure mechanical requirements. In cooperation with the department of physical metallurgy and materials testing at the University of Leoben as well as other project partners a novel Nb and Mo containing gamma-TiAl based alloy (TNM™ alloy) was developed. Due to optimized microstructure the alloy showed good malleability in first forging trials. An innovative approach of near conventional hot-die forging, which means that conventional forging equipment with minor and inexpensive modifications can be used, was made by BSTG.Aim of this project is to develop a robust low-cost near conventional hot-die forging process for low pressure turbine blades which meets on the one hand the requirements of the OEM and gives the right direction for future serial production on other hand.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Intelligent Shape Modeling' to be submitted under Seventh Framework.

assistant: **Abstract**

Digital 3D content creation and modeling has become an indispensable part of our technology-driven society. Any modern design and manufacturing process involves manipulation of digital 3D shapes. Many industries have been long expecting ubiquitous 3D as the next revolution in multimedia. Yet, contrary to “traditional” media such as digital music and video, 3D content creation and editing is not accessible to the general public, and 3D geometric data is not nearly as wide-spread as it has been anticipated. Despite extensive geometric modeling research in the past two decades, 3D modeling is still a restricted domain and demands tedious, time consuming and expensive work effort even from trained professionals, namely engineers, designers, and digital artists. Geometric modeling is reported to constitute one of the lowest-productivity components of product life cycle.The major reason for 3D shape modeling remaining inaccessible and tedious is that our current geometry representation and modeling algorithms focus on low-level mathematical properties of the shapes, entirely missing structural, contextual or semantic information. As a consequence, current modeling systems are unintuitive, inefficient and difficult for humans to work with. We believe that instead of continuing on the current incremental research path, a concentrated effort is required to fundamentally rethink the shape modeling process and re-align research agendas, putting high-level shape structure and function at the core. We propose a research plan that will lead to intelligent digital 3D modeling tools that integrate semantic knowledge about the objects being modeled and provide the user an intuitive and logical response, fostering creativity and eliminating unnecessary low-level manual modeling tasks. Ac
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Holistic integration of mcfc technology towards a most effective systems compound using biogas as a renewable source of energy ('EFFECTIVE')'.

assistant: **Innovation**

The Molten Carbonate Fuel Cell technology (MCFC) was developed with natural gas. The technical risks are still high even for natural gas as fuel. The MCFC-technology is feasible for Biogas as a fuel but needs significant RTD. Biogas as fuel to the known CHP's has been proven in the recent 10 years. However, electricity production out of Biogas is limited to low efficiency and with heat that in most cases can't be used in a reasonable way. MCFC enable the production of electricity, reducing the heat production (which is then valuable high temperature heat) to a minimum. MCFC using Biogas as fuel is a novel and innovative approach that has never before been taken into consideration. The MCFC's are most suited for using Biogas as fuel, and a Pre-Processing Unit will have to guarantee the gas standards for the MCFC. Because of the potential for MCFC/Biogas plants, the project will also focus on the integration of MCFC/Biogas plants in ES and SK. An experimental prototype will be installed in AT.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Mesoporous Photocatalysts for the Degradation of Persistent Organic Pollutants'.

assistant: **Innovation**

This proposal is for an IIF award to enable a researcher from India to visit a laboratory in the UK. The researcher wishes to develop: (i) new scientific skills; (ii) a lasting collaboration within the UK; and (iii) potential to increase the research capacity of his home research environment.The proposal aims at understanding chemical mechanisms and catalyst design factors that influence photocatalysed degradation of selected pesticides in aqueous solution. This understanding will be used to design and synthesise more efficient titanium dioxide photocatalysts for the destruction of priority organic pollutants.The latter will be achieved using nanoparticle production technologies to synthesize surface and composition modified photocatalysts. For the modification of catalyst composition, we propose to produce innovative P25 analogues by hydrothermal means - in particular, to independently control the rutile crystallite size, anatase porocity and anatase / rutile ratio and to optimize the photoreactivity of the catalyst with respect to those parameters. For the modification of catalyst surface, we propose to conduct a novel study of the efficiencies of photodegradation of hydrophobic and hydrophilic pesticides on samples of TiO2 that have been pretreated to render their surfaces highly hydrophilic and highly hydrophobic, so allowing to be made generic assessment of the respective efficiencies of dynamic and static photodegradation mechanism for each class of pollutant. We also propose to use the Quartz Crystal Microbalance as a technique by which substrate adsorption at the catalyst surface can be measured in real time and most especially during a photodegradation experiment. The determination of the intermediates and the mechanism through which the pesticides of interests
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Hypoglycaemia - REdefining SOLutions for better liVEs' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Diabetes is one of the most prevalent global non-communicable diseases, affecting  60 million people in Europe, 10% of whom with type 1 diabetes. Normalising elevated glucose levels decreases symptoms, prevents microvascular complications, improves cardiovascular health and saves lives, but creates a significant risk for hypoglycaemia when insulin treatment is required. Hypoglycaemia is a serious event associated with cognitive decline, reduced quality of life, cardiovascular events and mortality. Hypoglycaemia remains the principal barrier to achieve glucose levels necessary to prevent diabetic complications of chronic hyperglycaemia.The overall objective of Hypo-RESOLVE is to alleviate the burden and consequences of hypoglycaemia, to be achieved by answering several key questions through a unique public-private partnership. Hypo-RESOLVE will construct secure sustainable databases with data from 100-150 clinical trials offering huge statistical power to establish the glucose threshold(s) below which hypoglycaemia constitutes a risk for poor outcomes in various populations. This will provide valuable input for an evidence based classification of hypoglycaemia to be adopted by regulators, patient organisations and other stakeholders, for application in future trials, the clinic and epidemiologic studies. The basic science and translational research line of Hypo-RESOLVE will advance our understanding on mechanisms underlying consequences of hypoglycaemia and explore novel pathways for the restoration of impaired awareness of hypoglycaemia. Finally, we will determine the significance of CGM-detected low glucose and investigate psychological and economic impacts of hypoglycaemia to quantify the burden of hypoglycaemia both for the individual and next-of-kin, as well as for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Smart electrolyte with inherent flame-retardancy for next generation fire-safe lithium-ion batteries.'.

assistant: **Innovation**

Despite significant advancement in other characteristic requirements of rechargeable lithium-ion batteries (LIBs), safety threats to the rechargeable LIBs still persist. Main challenge of the safety concerns related to LIBs is heat accumulation during thermal runaway inside the cells, which is difficult to be eliminated due to poor thermal management associated with current technologies. In this context, the overarching aim of this ambitious yet achievable project (SMARTBATT) is to develop a thermoreversible liquid-solid transition (TLST) electrolyte integrated with inherent flame-retardancy for LIBs. The new idea of SMARTBATT is to design and synthesis flame-retardant thermoreversible liquid-solid transition electrolytes via the principals of the chemical Michael addition reaction (to incorporate flame retardant into electrolytes) and chemical Diels-Alder addition reaction (to produce liquid-solid transition in the electrolytes). In details, TLST will be comprised of Li-salt dissolved in a mixture of two organic solvents-vinylene carbonate and 2,5-dimethylfuran; as internal temperature of LIBs increases, both organic solvents will undergo a Diels-Alder addition reaction to form a supramolecular crosslinked network, as a result there will be a significant diminution in Li+ ion conductivity, led LIBs to non-operational mode. Moreover, TLST functionalized with 9,10-Dihydro-9-oxa-10-phosphaphenanthrene-10-oxide (DOPO) will offer excellent flame-retardancy to the electrolytes as fire hazard of LIBs appears. SMARTBATT is multidisciplinary and requires complementary expertise from the host (Polymer Chemistry and Physics, Fire Retardant Materials) and the researcher (Electrochemistry, Battery), is contributing to the new generation of LIBs, following the priorities of the Euro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'A bioprinting platform for the rapid, reliable, controlled and quantifiable patterning of cellular aggregates and microtissues into macroscale regenerative grafts with programmable architectures' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

A fundamental limitation with current approaches aiming to bioprint tissues and organs is an inability to generate constructs with truly biomimetic composition and structure, resulting in the development of engineered tissues that cannot execute their specific function in vivo. This is perhaps unsurprising, as many tissues and organs continue to mature postnatally, often taking many years to attain the compositional and structural complexity that is integral to their function. A potential solution to this challenge is to engineer tissues that are more representative of an earlier stage of development, using bioprinting to not only generate such constructs, but to also provide them with guiding structures and biochemical cues that supports their maturation into fully functional tissues or organs within damaged or diseased in vivo environments. It has recently been demonstrated that such developmental processes are better recapitulated in ‘microtissues’ or ‘organoids formed from self-organizing (multi)cellular aggregates, motivating their use as biological building blocks for the engineering of larger scale tissues and organ. The main goal of micro2MACRO (m2M) is to develop a new bioprinting platform capable of spatially patterning numerous cellular aggregates or microtissues into scaled-up, personalised durable load-bearing grafts and guiding their (re)modelling into fully functional tissues in vivo within damaged or diseased environments. This will be achieved using a converged bioprinting approach capable of rapidly depositing cells and microtissues into guiding scaffold structures with high spatial resolution in a rapid, reliable, reproducible and quantifiable manner. These guiding structures will then function to direction the fusion and remodelling of cellular aggre
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Promotion of pollution control and energy saving by use of hybrid power systems' under Fifth Framework.

assistant: **Concept**

This proposal is aimed at disseminating, through a 2-day congress and other measures, the results of two RTD projects in hybrid propulsion technology whose objective is to reduce fuel consumption and emissions in urban passenger transit vehicles. The technical objective of both these RTD projects is to maximise brake energy recovery and reduce the size and optimise the operation of the prime mover by use of an energy storage facility. It is aimed to meet EURO V and EEV emission standards. The congress is aimed at disseminating and promoting the technology to a wide European audience of transport planners, operators and vehicle builders, and also to other potential end users such as crane and delivery vehicle manufacturers. It will include demonstrations, workshops and an exhibition.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Stability Conditions, Moduli Spaces and Enhancements' under Horizon 2020.

assistant: **Concept**

I will introduce new techniques to address two big open questions in the theory of derived/triangulated categories and their many applications in algebraic geometry.The first one concerns the theory of Bridgeland stability conditions, which provides a notion of stability for complexes in the derived category. The problem of showing that the space parametrizing stability conditions is non-empty is one of the most difficult and challenging ones. Once we know that such stability conditions exist, it remains to prove that the corresponding moduli spaces of stable objects have an interesting geometry (e.g. they are projective varieties). This is a deep and intricate problem.On the more foundational side, the most successful approach to avoid the many problematic aspects of the theory of triangulated categories consisted in considering higher categorical enhancements of triangulated categories. On the one side, a big open question concerns the uniqueness and canonicity of these enhancements. On the other side, this approach does not give a solution to the problem of describing all exact functors, leaving this as a completely open question. We need a completely new and comprehensive approach to these fundamental questions.I intend to address these two sets of problems in the following innovative long-term projects:1. Develop a theory of stability conditions for semiorthogonal decompositions and its applications to moduli problems. The main applications concern cubic fourfolds, Calabi-Yau threefolds and Calabi-Yau categories.2. Apply these new results to the study of moduli spaces of rational normal curves on cubic fourfolds and their deep relations to hyperkaehler geometry.3. Investigate the uniqueness of dg enhancements for the category of perfect complexes and, most prominen