RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Discovery and Characterization of Third-Generation Nonlinear Photovoltaics' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

A central focus of leading investigations, the bulk photovoltaic effect is a nonlinear absorption process that converts light into electrical current intrinsically. The last few years have brought groundbreaking discoveries to the field, including an unprecedented enhancement of the photoresponse driven by a combination of topology and third-order electric-field effects, as well as the first material realization of solar-cell efficiency exceeding the upper-limit of current devices. The nonlinear mechanism is thus in an excellent position to revolutionize the field of solar-cell technologies by opening a fundamentally new route towards highly efficient third-generation photovoltaics. Reaching this landmark requires both a fundamental understanding and a systematic search of materials. In this scenario, first-principles calculations based on density functional theory must play a central role in coming years due to their innate ability to deliver microscopic and material-specific predictions. A first-principles description of nonlinear responses, however, is very complex and contemporary methods need to go far beyond the state-of-the-art for modelling central effects such as third-order contributions. PhotoNow aims at filling this critical gap by developing a first-principles method that correctly incorporates these effects, giving unprecedented access to crucial properties like the energy conversion efficiency. Our methodology will rest upon a Wannier-function technique adaptable to any material, crystallizing in a free software interdisciplinary tool aimed for physicists, chemists and engineers. This major development will allow us to achieve our central goal, namely discovering and characterizing outstanding materials for nonlinear photovoltaics. PhotoNow will carry out
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'ToxMate: Automated on-line and real-time monitoring of wastewater toxicity with ToxMate' in the context of a Horizon 2020 call.

assistant: **Objectives**

Urban centres, industries and agriculture produce large volumes of wastewater; in addition, the current population growth, accelerated urbanization and economic development are increasing the quantity and pollution of wastewater globally. Being a by-product of human activities, wastewater contains chemical, biological and physical pollutants, so it must be treated to remove all contaminants before it is released in the environment. Releasing untreated or inadequately treated wastewater is dangerous and has harmful effects on human health, the environment, and economic activities.  Water quality after wastewater purification varies over time, even and especially during one single day, but managers do not have the necessary tools to monitor these variations. Currently available methods based on bioassays or physical and chemical parameters require sampling, conservation and transport, and are based on spot-sampling (1-2 times/year). These methods are not able to provide information on temporal variability and have low efficiency, durability, and specificity; they are also slow in providing results (at least 72 hours) and can’t allow real time monitoring. To overcome these limitations, ViewPoint has developed ToxMate: a tool for the automated real-time, on-site and on-line monitoring of wastewater toxicity. It is based on the simultaneous analysis of the locomotor behaviour of 3 different species of aquatic invertebrates and it uses infrared light and powerful and precise cameras to record continuously the activity of the animals. The system is composed of 3 panels, each containing 16 animals, so 48 animals can be analysed at the same time and for up to 30 days. ToxMate is fast: it can provide a result on water toxicity in just one hour, so it allows public authorities and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Screen embedded reading glasses - a revolutionary optical technology that eliminates the need for reading glasses while using digital devices.' (2021-2027) targeting Horizon Europe.

assistant: **Abstract**

Our groundbreaking solution allows people who suffer of vision impairment to view sharply the screen of any device (smartphone, car display, etc.) without using their glasses. This, among other uses, can allow drivers to put their maximum focus on the road. VISION_GLASS is flexible, thin (less than 0.5mm), transparent foil applied to the display surface comprised of multi layers of tiny invisible micro-optical elements that are used for imaging. This solution will benefit millions of people suffering from presbyopia, and it is possible thanks to our innovative optical technology- Image Projection MLA. VISION_GLASS is a IP-MLA film consists of arrays mutually aligned in a very specific pattern between the positive and negative lenses to form multi–MLA layers of micro-optical elements that create an image at infinity at the user's eye. It is a revolution in the market of reading glasses.


**Keywords:** digital display innovation,road safety,vision correction,micro lens array,inclusive work environment
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Integrated system for intelligent regional environmental monitoring & management' in the context of a Fifth Framework call.

assistant: **Objectives**

ISIREMM addresses the problem of industrial pollution, and in particular air Pollution, and its effects on the human and natural environment. In a rapidly changing economic environment there are unique opportunities to include environmental concerns in the ongoing restructuring of heavy, and heavily polluting, industries as well as domestic energy use. To do this efficiently the project will be using the results of a FW4 Environmental Telemetric Project as the starting point, adapting it to the specific NIS conditions and extend it with a number of advanced optical and acoustical monitoring methods developed at the NIS partner institutions into a new environmental management information system. The system will be tested in an implementation for the city of Toms, Siberia.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Ultrafast X-Ray Tomography of Turbulent Bubble Flows' in the context of a Seventh Framework call.

assistant: **Objectives**

Multiphase reactors are omnipresent in chemical engineering and dominate today's manufacturing of chemical products such that they are present in most of our daily products. That implies a huge economic and ecologic impact of the reactor performance. The basic idea of a multiphase reactor is to contact chemical precursors and catalysts in a sufficient time for the reaction to proceed, but reactor performance is crucially affected by the complex reactor hydrodynamics. A proper optimization would imply that multiphase flows are adequately understood.Gas bubbled into a pool of liquid is the simplest example of a multiphase reactor. Bubble columns or distillation columns, however, house millions of bubbles emerging in swarms with interactions such as coalescence and breakage events that determine the whole process behaviour. The understanding of such disperse gas-liquid flows is still fragmentary and requires a ground-breaking update.The aim of the project is to apply the worldwide fastest tomographic imaging method to study such turbulent gas-liquid dispersed flows in column reactors such as bubble columns and tray columns. The project intends to provide unique insights into the bubble swarm behaviour at operating conditions that have been hidden so far from the engineer's eyes.The project is foreseen to enhance the fundamental understanding of hydrodynamic parameters, evolving flow patterns and coherent structures as well as coalescence and breakage mechanisms, regardless of if the systems are pressurized, filled with particle packings, operated with organic liquid, slurries or with internals.The interdisciplinary team shall re-establish the process intensification route for multiphase reactors by a new understanding of small-scale phenomena, their mathematical descriptio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'A synthetic biology approach for magnetization of foreign organisms by genetic engineering and transplantation of bacterial magnetosome biosynthesis' (SYNTOMAGX) targeting Horizon 2020.

assistant: **Abstract**

An immensely valuable asset to the field of synthetic biology would be a means to genetically endow magnetism to living organisms, which is still an unsolved challenge due to the lack of appropriate tools. In contrast, biomagnetism is innate to magnetotactic bacteria, mud-dwelling microbes which as geomagnetic sensors biomineralize iron nanocrystals with exceptional properties, the magnetosomes. However, transplantation of magnetosome biosynthesis has remained unachieved for many years, owing to its complexity and lack of knowledge of genetic determinants. Recently, my lab discovered relevant biosynthetic gene clusters and for the first time succeeded in expressing them in a foreign bacterium. Inspired by this major breakthrough, I now propose a step change approach for endogenous magnetization of diverse organisms based on bacterial magnetosome biosynthesis. By combining systematic genetic reduction with bottom-up redesign we will first minimize the pathway to make it universally portable. We will then reprogram E. coli into a chassis for plug-in expression of diverse magnetosome gene sets. By harnessing determinants of structurally diverse magnetosomes from various bacteria, we will reconfigure the pathway for mix-and-match generation of designer nanoparticles with tuned magnetic properties. Finally, we will attempt to reconstitute key parts of magnetosome formation in eukaryotic hosts by using yeast mitochondria as a universal model. The overall aim is to generate a versatile synthetic toolkit for genetic magnetization of different organisms. This would represent a quantum leap with tremendous impact on various fields of biomedical research and biotechnology. It might be exploited for bioproduction of tailored magnetic nanomaterials with novel and tunable properties.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'New X-Ray Imaging Sensors' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

WP1. Integrated detector based on high quality epitaxial GaAs.Detectors made from semi-insulating GaAs have been bonded to integrating and photon counting read-out chips. High purity VPE GaAs layers have been produced. The properties of the layers have been tested in prototype detectors.WP2. Pixel array based on a CdZnTe sensor bonded to a CMOS readout chip.Semi-insulating GaAs and CdTe detectors have also been bonded to integrating and photon counting read-out chips. We have shown that GaAs and CdZnTe detectors can be reliably bump bonded to readout chips with a pitch of 38 um and even down to 25 um.WP3. Silicon CCD coated with a high efficiency pixel aligned scintillator.Initial tests produced scintillating layers of BGO by laser ablation. However it turned out to be difficult to etch pixel structures in these layers. An alternate method was then introduced: A grid structure was etched in silicon and the grid was subsequently filled by a scintillating material. The results obtained with this structure are promising. The structure has been given the name Scintillating Guides Screen. A patent has been applied for. Objectives and content Digital X-ray imaging systems are now replacing X-ray film in a number of fields. The main reasons are time savings since digital images do not require photographic development and that image processing can be introduced to assist the viewer in the interpretation of the image. The main limitation in the current systems is that the sensor cost is high related to the effectiveness. This proposal concerns research in order to reduce the cost and increase the sensitivity of the sensor. The most important application areas for digital X-ray imaging are in medicine and dentistry since the new technique leads to a reduction of the X-ray dose to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Surviving metabolism: acid handling and signalling' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Metabolism generates vast quantities of acid, which exerts broad-spectrum biological effects because protein protonation is a powerful post-translational modification. Regulation of intracellular pH (pHi) is therefore a homeostatic priority, but carefully orchestrated proton dynamics are a versatile signal.Extracellular acidity is an established chemical signature of tumours and has recently been proposed to convey a signal that shapes the phenotypic landscape of cancer. Cancers genetic instability yields diversity in acid handling and signalling, forming a substrate for selection under acid-stress. This is a plausible mechanism for disease progression and an analogy can be drawn to experimentally-verified hypoxic selection.Current models of acid handling in cancer are, however, based on population-averages of observations made at the cell level. This fails to appreciate diversity and the complexity inherent in tissues. We will produce a more complete understanding of acid handling that accounts for diffusive transport across tissue compartments and the role of the tumour stroma. A systems-approach of characterising pH-regulatory processes cell-by-cell will identify which components are liable to vary, and thus are a substrate for acid-driven somatic evolution.The long-term effects of proton signals on gene expression have not been tested, despite evidence for proton-sensing transcription factors. To address the mechanism for adaptation to acid-stress, proton-sensing transcription factors will be characterised from studies of gene expression under chemically and optogenetically operated pH stimuli.The definition of a cells fitness to survive at a particular microenvironment pH and its relationship with stemness remain unclear. Phenotyping pHi-gated subpopulations in ter
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Powdery Mildew Resistance' under Horizon Europe.

assistant: **Concept**

Plant diseases lower crop yields significantly, and thereby threaten food-security worldwide. Powdery mildew fungi is a severe pathogen on numerous food-crops. Generating food-crops resistant to these fungi would be a major step forward in the continuous fight between plants and pathogens, and it would tip the balance in the favor of food-security. The proposed project will majorly contribute to this goal by elucidating the immunity related processes occurring upon fungal infection and will allow to develop breeding strategies to heighten plant immunity. The barley powdery mildew fungus (Blumeria hordei) causes disease by secreting hundreds of effector proteins into the barley tissue. One of the hallmarks of immunity is the formation of a structure called papilla, at the site of fungal penetration, which limit the damage to the plant. Evolutionary adapted fungi can easily overcome this. However, the pathway for secretion of proteins and other components to the papilla is not well understood. There is thus a need to increase our understanding of how this secretion process occurs during immunity. My host lab has uncovered that the membrane trafficking leading to papilla formation occurs by novel mechanisms not previously studied in plants. In the proposed project, I will explore this highly complex field by identifying a list of fungal effectors which target this pathway, and I will use these effectors to find specific components of it. Ceramides are predicted to play a role in the secretion of extracellular vesicles during this papilla formation in mammals, therefore, I will additionally take a targeted approach to characterize their role in plants. My strong background and solid track-record, the expertise and experience of the host supervisor, together with the infrast
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Engineering in vitro microenvironments for translation of cell-based therapies for tendon repair' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Tendon Therapy Train is a research, training and innovation programme for human and equine tendon repair and regeneration that will exploit recent advancements in tissue engineering by self-assembly (TESA) technologies which have led to the clinical translation and commercialisation of advanced therapy medicinal products (ATMPs).  Although TESA therapies have the potential to revolutionise healthcare for numerous clinical targets, a lack of researchers with the necessary interdisciplinary skillset to advance the field is limiting clinical translation.  Tendon therapy train, a network of 8 beneficiaries and 8 partners (7 universities, 7 companies and 2 hospitals) from six countries across Europe, will train a cohort of 15 researchers to doctoral level in the interdisciplinary area of ATMPs.  The innovative credentials of the research and training programme involve engineering suitable ex vivo culture environments that, by mimicking the native tendon tissue milieu (human and equine), will maintain the tenogenic phenotype  of tendon derived cells and differentiate non-tendon derived cells (stem cells and dermal fibroblasts) towards the tenogenic lineage, subsequently enabling development of three-dimensional cell-assembled tissue equivalents, the clinical potential of which will be assessed in suitable preclinical models.  The comprehensive Tendon Therapy Train programme will equip researchers with transferable inter- and multidisciplinary skills that will further European-based knowledge, innovation, competitiveness and leadership in the field of TESA / ATMP and ultimately enable clinical translation and commercialisation of the developed technologies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Bridging Diplomatic Divides through the Rights of Nature: European and Latin American Approaches to Redefining Sustainable Development at the United Nations'.

assistant: **Objectives**

“Bridging Diplomatic Divides through the Rights of Nature: European and Latin American Approaches to Redefining Sustainable Development at the United Nations” (NATURE-BRIDGES) investigates whether the European Union (EU) and Latin America (LA), as political groups within the UN, share common ground in their approaches to the Rights of Nature (RoN), and to what extent such convergence could contribute to redefining sustainable development in UN multilateral negotiations - or if their positions reflect fundamentally divergent normative and diplomatic frameworks. Although both regions have pioneered legal and policy innovations in RoN, it remains underexplored why they often adopt opposing stances in UN fora. This project examines the extent to which these divergences are reconcilable and what they reveal about the future of global sustainability governance. To this end, the project first compares the normative, legal, and institutional approaches to RoN in both regions to assess whether their differences stem from underlying principles. Second, it analyzes their positions within the UN Harmony with Nature agenda to determine if diplomatic misalignment, rather than normative divergence, explains their lack of coordination. Third, it explores the influence of transnational networks - particularly those linked to Harmony with Nature - on shaping Member States’ diplomatic positions at the UN to support alternative development paradigms. Based on the findings and as policy-oriented outcome, NATURE-BRIDGES proposes a diplomatic framework for integrating the RoN into the post-2030 UN Sustainable Development Agenda. The project will be hosted at Leiden University.


**Keywords:** Rights of Nature; Sustainable Development; European Union; Latin America; United Nations