RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'EU-China Innovation Platform on Sustainable Urbanisation' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The key objective of URBAN-EU-CHINA is to develop a robust, evidence-driven bottom-up approach to complement the existing top-down EU-China strategic approach to sustainable urbanisation. This will be accomplished via a coordinated series of actions including: a strategic R&I agenda, scoping and assessment, networking events, peer-to-peer exchanges, benchmarking and monitoring, and joint demonstration projects. By creating tighter coupling between city-level, national, and supra-national programmes, planning, policies, and projects, URBAN-EU-CHINA will yield a significant increase in cooperative EU-CHINA R&I activities.The key barrier addressed by URBAN-EU-CHINA is the disconnect between strategic visions and targets and operational realities of time/resource constraints, language and cultural barriers, differences in planning/policy/ governance framework conditions within European and Chinese cities, and lack of effective bi-directional transmission mechanisms of transferable planning and policy instruments for sustainable urbanisation.The topic ENG-GLOBALLY-08-2016-2017 asks for the creation of an EU-China Innovation Platform on Sustainable Urbanisation. Creating such a platform is complex and cross-sectoral by nature, aiming to engage policy makers, national authorities, industries, cities, academia, civil society and other stakeholders in order to develop more sustainable cities. In URBAN-EU-CHINA, 12 experienced European and Chinese consortium partners from across the sustainable urbanisation value chain join forces to support the European Commission in its aim to make EU-China sustainable urbanisation cooperation more accessible, attractive, and rewarding for a broader set of stakeholders.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Generation and Application of Nucleophilic Allylmetal Species by Catalytic 1,4-Metal Migration', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

This proposed Fellowship brings together an Experienced Researcher from India with expertise in click chemistry, transition metal catalysis, and topochemical synthesis, with an internationally recognized Host Laboratory in the UK with expertise in the development of new catalytic reactions for organic synthesis. This project will:• Provide high-quality, tailored training for an outstanding scientist (possessing an excellent publication record) who is primed for an independent research career by complementing and enhancing his competencies.• Enhance European excellence in organic synthesis and catalysis, which are fundamentally important branches of chemistry that greatly impact upon many fields, such as the fine chemicals, pharmaceutical, agrochemical, materials, and biochemical industries.The proposed research is based upon a completely new synthetic method recently discovered in the Host Laboratory that enables the generation of nucleophilic allylmetal species, which are widely employed in organic synthesis to prepare diverse compounds of interest. This method involves the catalytic carbometallation of the alkyne of a 1,3-enyne, followed by 1,4-migration of the resulting alkenylmetal species to the cis-allylic position of the enyne, which constitutes a special type of C–H functionalization reaction. The resulting allylmetal species may then be trapped by an electrophile stereoselectively. It is our strong conviction that the possibilities of this chemistry are enormous, and the end result will be a generally useful synthetic method for the preparation of valuable building blocks as single enantiomers. This fellowship will therefore help Europe to remain globally competitive in the chemical sciences.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Creating Learning Organisations with Contextualised Knowledge-Rich Work Artifacts' (CLOCKWORK) under Fifth Framework.

assistant: **Objectives**

In innovative companies, knowledge is intrinsically linked to the tools of work. Despite this, current approaches to knowledge sharing and reuse fail to integrate these tools into the learning organisation. These companies are also faced with the contradiction of needing to collaborate with other companies whilst protecting the private knowledge that gives them competitive advantage. The CLOCKWORK project focuses on the engineering domain. It will combine knowledge rich dynamical simulation tools, formal documentation and informal rationale to closely integrate working, learning, collaboration and negotiation, within and between organisations. This involves the extension and integration of previous work on agents, knowledge modelling, document discourse tools, simulation and machine learning.The CLOCKWORK business objectives are to support:1) open knowledge sharing within distributed teams for work practice improvement,2) knowledge reuse within an organisation for productivity enhancement and innovation stimulation, and3) cautious knowledge sharing for collaboration and trade between innovation companies.Objectives:Integrating working and learning is essential within innovative commercial areas. Trading and collaborating while safeguarding sensitive commercial knowledge is crucial to survival and success. Neither of these commercial needs are successfully supported by current technologies. CLOCKWORK focuses on engineering knowledge created and contained in dynamical simulation models. The project integrates simulation tools with formal documentation, informal design rationale and formal knowledge models to support working while learning and provide a collaboration and trading framework for innovative competitive companies.The objectives are to support:1. Knowledge shari
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Alpha Shape Theory Extended'.

assistant: **Objectives**

Alpha shapes were invented in the early 80s of last century, and their implementation in three dimensions in the early 90s was at the forefront of the exact arithmetic paradigm that enabled fast and correct geometric software. In the late 90s, alpha shapes motivated the development of the wrap algorithm for surface reconstruction, and of persistent homology, which was the starting point of rapidly expanding interest in topological algorithms aimed at data analysis questions. We now see alpha shapes, wrap complexes, and persistent homology as three aspects of a larger theory, which we propose to fully develop. This viewpoint was a long time coming and finds its clear expression within a generalizedversion of discrete Morse theory. This unified framework offers new opportunities, including(I) the adaptive reconstruction of shapes driven by the cavity structure;(II) the stochastic analysis of all aspects of the theory;(III) the computation of persistence of dense data, both in scale and in depth;(IV) the study of long-range order in periodic and near-periodic point configurations.These capabilities will significantly deepen as well as widen the theory and enable new applications in the  sciences. To gain focus, we concentrate on low-dimensional applications in structural molecular biology and particle systems.


**Keywords:** computational geometry, computational topology, algorithms, alpha shapes, persistent homology
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'A Theory of Soft Synergies for a New Generation of Artificial Hands' (2007-2013) targeting Seventh Framework.

assistant: **Abstract**

Although many advances have been made in the mechatronics andcomputational hardware of artificial hands, the state of the artappears to be only marginally closer to a satisfactory functionalapproximation of the human hand than it was twenty years ago. Inmy analysis, the main reasons for this are not merely techni-cal,but invest some fundamental issues in the understanding of theorganization and control of hands, and ultimately the lack of atheory to guide us in the search for a principled approach totaming the complexity of hands.  In this project, I propose tocontribute to the development of the fundamental elements of sucha theory, and bring them to fruition in functional engineereddevices. I expect to be able to break through the rather slowlymoving front of the state of the art because of the combinationof two crucial, recent innovations. The first pillar, and theprime theoretical enabler for this program, is an approach to thedescription of the organi-zation of the hand sensorimotor systemin terms of geometric constraints, or synergies: correlations inredun-dant hand mobility (motor synergies), correlations inredundant cutaneous and kinaesthetic receptor readings (multi-cueintegration), and overall sensorimotor controlsynergies. Elements of such theories have emerged recently inneurosciences, but their exploitation in the sciences of theartificial is an enormous potential barely touched upon tillnow. The second pillar, providing the new technology needed tobuild simpler and more effective artificial hands, is theunderstanding of the role of variable impedance actuation inembodying intelligent grasping and manipulation behaviours inhumans, and the availability of a new generation of “robotmuscles”, i.e. actuators capable of tuning their impedance toadapt to the envi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Evolution of white dwarfs with 3D model atmospheres' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The vast majority of stars will become white dwarfs at the end of the stellar life cycle. These remnants are precise cosmic clocks owing to their well constrained cooling rates. They provide one of the most sensitive tests of when baryonic structure formation began in the Universe. These compact matter laboratories also unravel the mass-loss in the post-main-sequence evolution and establish critical constraints for galactic evolution models. I will design a robust theoretical framework to shed new light on the interior structure of white dwarfs, associate them with their progenitor stars, and enhance their potential as probes of fundamental astrophysical relations. I have recently computed the first 3D simulations of pure-hydrogen white dwarf atmospheres including full radiation-hydrodynamics. These improved calculations demonstrate that the widely used 1D model atmospheres are unable to correctly solve the thermodynamic stratification of convective layers, and therefore lead to incorrect masses and cooling ages. My ambitious goal is to expand the 3D simulations to stellar remnants of all atmospheric compositions and connect these surface calculations to interior structure models. The project is timely since my improved theoretical tools will be essential to analyse the forthcoming Gaia sample, where the number of known white dwarfs is expected to increase by a factor of ten. I will use my theoretical framework with Gaia data, supplemented by other surveys and dedicated follow-up observations, to extract an unprecedented wealth of information from white dwarfs. I will set the standards for the star formation history and initial mass function in the Milky Way, as well as constrain the fundamental mass-radius relation for white dwarfs. I will also study evolved planetary
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The domestication, evolution, and adaptive role of horizontal gene transfer in eukaryotes.' under Horizon Europe.

assistant: **Concept**

The emergence and acquisition of new genes play a crucial role in the evolution of eukaryotes, providing new functions that contribute to adapting to changing environments and conquering unexplored niches through cellular innovations. Horizontal gene transfer (HGT), defined as the acquisition of genetic material from different species, has been shown to play a key role in eukaryotic genome evolution. HGT, particularly from bacteria and viruses, provides unprecedented adaptive potential by introducing novel functions into eukaryotic cells. However, new genes are often quickly lost because important constraints and evolutionary barriers need to be overcome for successful integration into the host genome. Despite the importance of HGT for eukaryotic biology, how this process works is still unclear and the mechanisms that contribute to the domestication of foreign genes, especially at the early stages, are unexplored. This project aims to develop a new experimental model for investigating HGT in eukaryotes using the green alga Chlamydomonas reinhardtii. For this, a bacterial antibiotic resistance gene (aphVIII) will be randomly integrated into the C. reinhardtii genome and its real-time functionalisation and evolutionary trajectories will be tracked. Using experimental evolution, I will identify genomic features that have a major impact on the control and stability of new genes. Additionally, I will analyze how HGT contributes to adaptation and impacts evolutionary flexibility in different scenarios. Finally, I will survey green algal diversity to understand how HGT contributed to the evolution of chlorophytes. Hence, this interdisciplinary project, combining molecular biology, experimental evolution, and computational methods, will offer unprecedented insights into the mec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Promoting ecosystems and regional development - in support of regional operational support of regional operational programming' (PEARDROP) targeting Sixth Framework.

assistant: **Abstract**

The principal focus of PEARDROP is to make more accessible and more practicable for regional policy makers and key local actors the instruments for exploitation and adoption of research and deployment results in ICT for Enterprise Networking and, in particular, in Digital Ecosystems. PEARDROP aims to draw together the most salient results of the innovation and digital business ecosystem cluster of FP6, including some first regional deployment experiences and results, converting these where necessary into 'layman's' terms, as well as into a number of EU languages (minimum 5), with a view to making them more accessible and of more practicable use to regional policy makers, especially those concerned with regional operational programming and with eBusiness development.PEARDROP expects to increase significantly the number of regions that are interested to adopt it, and actively participate in, or considering deployment of, innovation and digital business ecosystem research and models. PEARDROP will seek to better understand critical success factors in terms of the behaviour of regional development agents, and will propose systems (tools, methodologies and models) for assessing the risks and barriers, as well as the benefits and effectiveness, of such approaches and related policy interventions with a view to supporting regional policy makers and programmers in formulating more effective policies.PEARDROP acknowledges and will take due account of the diversity of European regions and the inter-regional variations of context and conditions that exist. PEARDROP does not propose to identify, develop or promote a single DBE approach or deployment model but rather to collaboratively define alternative approaches or models that could be adopted according to specific regional circu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Deciphering the developmental roots of childhood sarcoma cells – combining single cell sequencing technologies and machine learning' under Horizon 2020.

assistant: **Concept**

Each year more than 35,000 European children and young people are diagnosed with cancer. Childhood cancer remains a major public health and socioeconomic issue in Europe and around the world. Cancer arises when a single cell transforms and divides uncontrollably, resulting in a malignant mass of tumour cells. To study cancer, we must understand how these normal cells change. Our current understanding of how normal cells vary across the many tissues of our body is poorly understood. Child development represents a unique challenge in understanding our cells, as children’s bodies change at a cellular level entirely different than adults. This is reflected in the spectrum of cancers diagnosed in children compared to adults, particularly in bone and soft tissue cancers (sarcomas) where they present in less than 1% of adults' cancers and nearly 21% of children's cancers. With the advent of high-throughput single-cell RNA sequencing (scRNA-seq), it is now possible to analyze cell populations at remarkable scale and resolution. The primary purpose of this project is to use scRNA-seq to reconstruct the phylogenetic cellular lineage of childhood and adult sarcomas, and corresponding normal tissue. This fellowship aims to (1) discover and define differences between normal and cancer cell biology at single-cell resolution and (2) use machine learning to determine the cell type (cell-of-origin), the somatic changes and transcriptional trajectories of normal cells that lead to malignant transformation in children compared to adults.This project represents the highest resolution map of the intratumour genetic heterogeneity and clonal evolution of sarcoma ever produced. Another outcome of this project will be a reference map of all of the somatic mutations and expression profiles of no
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'On- and offline-Networks for Event Aware Topological detection' to be submitted under Horizon 2020.

assistant: **Abstract**

Imaging methods enabling the acquisition of millions of cell contours have opened the path for improved understanding of development, repair, homeostasis and pathology. The full potential of such imaging methods can only be reached when robust, cost-effective and user-friendly methods are democratized to extract important information from the huge amounts of data generated. Our project aims to implement a disruptive deep-learning based technology, O-NEAT, that uses these masses of data for training neural networks to automatically and reproducibly explore tissue dynamics. This would enable researchers in academia and the private sector to quickly and reliably extract information regarding cell dynamics in normal or pathological conditions thus having significant potential market applications.


**Keywords:** Live-imaging, Image analysis, Software, Deep-Learning, Artificial intelligence Microscopy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Reassessing Realism over Universals in the Time of Peter Abelard' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

This three-year GF will bring Caterina Tarlazzi at the University of Notre Dame (USA) and at Ca’ Foscari University of Venice (Italy), where she will be supervised by, respectively, Richard Cross and Marco Sgarbi. The overall aim of the project is to investigate a neglected, though highly significant, topic in the history of the Problem of Universals: realist theories over genera and species in the Latin tradition, c. 1090-1160. This topic has the potential to bridge the gulf now existing between analytical and historical approaches to philosophy, drawing illuminating comparisons between medieval realism and contemporary analytic views over universals (especially the so-called ‘scientific realism’ of David Armstrong, Michael Loux’s ‘constituent ontology’, and the ‘new essentialism’ of Brian Ellis). It will also re-shape important aspects of the history of medieval philosophy regarding both the Latin 12th-century (where ‘realist’ notions seem to be found in Peter Abelard’s anti-realist philosophy) and its relations to later medieval philosophy (especially the 14th-century forms of realism of, among others, Duns Scotus, Walter Burley, and John Wyclif). The topic has, however, remained almost entirely neglected so far. This is mainly because a number of relevant sources are found in manuscripts scattered around Europe, which have never been published but are familiar to Tarlazzi thanks to her three-year British Academy postdoctoral fellowship at the University of Cambridge. Tarlazzi’s past experience and the training planned during this GF now allow for an in-depth study of these sources, which will yield a complete reassessment of 12th-century realism. The results will be disseminated both within academia and to a wider audience. The project has important implications for