RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Control of Hydrogen and Enriched-hydrogen Reacting flows with Water injection and Intensive Strain for ultra-low Emissions' (OTHERWISE) under Horizon Europe.

assistant: **Objectives**

We are racing against time to find a clean, yet abundant, energy source able to arrest global warming. Hydrogen has all the characteristics to address this challenge: it can be produced cleanly from water; it is incredibly energetic; and more importantly, it is carbon-free. However, hydrogens strong reactivity and diffusivity make the control of its flame in energy-generation devices extremely challenging. Moreover, toxic nitric oxides (NOx), a major concern for air quality, are still abundantly produced in a hydrogen flame. Enabling the use of hydrogen requires thus solutions where the flame is stable and with ultra-low NOx at the same time, and at any power setting.In this research I will study, for the first time, the combination of intensive strain and water injection in the context of lean premixed combustion. My preliminary research has indicated that intensive strain improves the reactivity of the hydrogen flame and simultaneously pushes the NOx down significantly, a property yet to be understood. Water injection further pushes down the NOx, but it commonly causes flame extinctions and inefficiencies. Its combination with hydrogen and intensive strain, by enhancing the flame, offers a way of surpassing these limitations, and further allows to operate the flame at richer conditions, so preventing common instabilities from occurring in lean premixed combustion.The objective of this research is to push the hydrogen flame into a high-strain regime characterised by stable flame and ultra-low NOx, and find the extreme limits and physical knowledge allowing full control of the reacting flow in such a regime. The flame dynamics, still unknown in this regime, will be explored for the first time and fully characterised in this research by using high-fidelity simulations, e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Support action to contribute to the preparation of future community research programme in user centred Design for ECO-multimodal MOBILity' under Seventh Framework.

assistant: **Concept**

DECOMOBIL will take advantage of the structured research network set up in HUMANIST NoE and followed up in HUMANIST VCE, in order to develop and widely disseminate knowledge in the area of human centred design of ICT for sustainable transport. Expected impacts of DECOMOBIL are: widening the market for ICT based mobility and transport services by contributing to the development and the widespread of user-friendly innovative nomadic services, impacting bicycles, public transport and car-sharing use through the understanding of multimodal travelers needs; by setting up design recommendations for the next generation of cooperative systems and improving integrated road transport system; by analysing long term effects and potential impact of ITS deployment on clean and safe multimodal mobility and improvements in efficiency and environmental friendliness of mobility and transport in Europe by improving eco-driving behavior leading to the decrease of vehicles carbon emission for car, bus and trucks and by understanding human behavior critical parameters linked to the implementation of electric mobility system. For this, activities in DECOMOBIL will provide understanding on acceptability and usability of ICT for the population, and setting up design guidelines and recommendations to avoid misuse and to allow user-friendly interaction with ICT functionalities. Through organisation of scientific seminars and international conferences, definition of road mapping for future research priorities, reflection on JRIs, and dedicated structured contributions to the eSafety forum in the framework of the iCar Initiative and any relevant committees in this area, objective of the DECOMOBIL project is to contribute to the acceptability and the usability of ICT for cleaner and safer mobility t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Organics over the Ocean Modifying Particles in both Hemispheres' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Considering its size and potential importance, the ocean is surprisingly poorly characterised in terms of organic gases that play important roles in global atmospheric chemistry. In this project we aim to characterise the nature of organic trace species, i n particular organic oxygenates, and the rate of emissions from marine biology. The oxidation of these compounds in air is directly linked to the global ozone budget while the oxidation pathways in seawater are largely unknown. We will conduct laboratory e xperiments on seawater samples and specific phytoplankton types to determine the effect of basic biophysical parameters (e.g. temperature, pH, plankton growth rate and physiological state) on the emission of organic species. The photooxidation rates and pr oducts of these species will be examined through measurements. Marine aerosols, with emphasis on the organic fraction, will also be investigated in terms of physical, chemical (mass closure), hygroscopic and optical properties. Two shipborne research cruis es will be performed to assess both emission and uptake in the open ocean, and contrast the pristine tropical Southern Hemispheric with the more strongly anthropogenically affected Northern Hemisphere. Based on the laboratory and field measurements an inte ractive atmosphere-ocean chemistry model will be developed, basic to global Earth system simulations.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Computational methods and modeling to decipher organelle nanophysiology' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Neuronal and glial physiology in nanodomains remains poorly understood due to the spatio-temporal limitation of direct unperturbed in vivo measurements. Yet, it is the scale of voltage regulation, ionic, proteins and molecular trafficking, metabolism control and local signal transduction. The goal of this proposal is to determine how the flow of ions and molecules is regulated in the cytoplasm in relation with organelles, such as the endoplasmic reticulum and mitochondria in various physiological conditions such as steady-state, induction of plastic changes or ionic depletion. The approach is based on mathematical modeling, large data analysis, simulation methods, and developing the associated fast and efficient algorithms. We developed in the past 15 years computational tools such as molecular modeling, stochastic simulations and data analysis at a molecular level to study various signals such as voltage recordings or super-resolution microscopy single particle trajectories (SPTs).  However, these theoretical approaches are not sufficient today to face the novel data revolution coming from SPTs, but also voltage dyes, voltage recorded by nanopipettes, or photoconversion in nanocompartments. The aim of the project is to develop physical models of molecular diffusion and electro-diffusion. These models will be applied to reconstruct and interpret the local transport, which is not homogeneous because molecules or receptors could aggregate in some specific nano-regions. We will explore the mechanisms underlying this heterogeneity. Second, we will apply these modeling and numerical simulations to analyze data about flux regulation inside the cytoplasm but also in organelles, such as the ER and mitochondria.Third, we analyze calcium fluorescent data (photoactivation, local u
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Regional development and cultural landscape change: the example of the alps. evaluating and adjusting eu and national policies to manage a balanced change' to be submitted under Fifth Framework.

assistant: **Abstract**

The overall project objective is to investigate the interrelation between regional development and cultural (=man made) landscape change. In a future oriented approach the team will propose improvements and adjustments to policies on EU and national level. The proposals are based on this new understanding in order to meet future requirements and to manage a balanced change in the Alps and other European landscapes and regions. The project will be carried out in close inter- and Tran disciplinary co-operation between the research team, local actors in the pilot regions selected and EU and national governmental bodies concerned. The results will be transferred to other European regions through a permanent process of experience exchange.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'LaRge-scalE implementation of COmmunity based mental health care for people with seVere and Enduring mental ill health in EuRopE' (RECOVER-E).

assistant: **Innovation**

For nearly 900 million people living in Europe, mental disorders constitute the most significant yet most neglected public health problem: depression affects an estimated 30.3 million Europeans, snf psychotic disorders 5 million Europeans. People with severe and enduring mental ill health want the same things out of life as other citizens but are often placed in a vulnerable position and are hence afforded less opportunities to attain their goals and thus experience a lower quality of life, and have a lower life expectancy compared to the general population. For many countries that have undergone mental health services reform or have health systems in transition, efforts to make such comprehensive community-based mental health services available resulted in short-lived outcomes or are still to demonstrate substantial impact.  RECOVER-E’s aims to ensure well-functioning community mental health teams in 5 countries in Europe (Macedonia, Romania, Bulgaria, Croatia, and Montenegro), which will serve as the central node for coordination and provision of care for people with SMI. Our project narrows the implementation  gap by going beyond infrastructure changes and pursuing the development of human resource capacity and care pathways that can be distilled in a comprehensive pathway to scale for regional and national decision-makers for uptake after the project’s life span. RECOVER-E will: 1) Develop evidence based care pathways and treatment protocols for transition to scale for regional and national decision makers in 5 implementation sites; 2) Establish a peer to peer capacity building partnership in community mental health by linking a European expert panel with key stakeholders in 5 implementation sites  to co-create community mental health services for people with SMI) 3
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'A genome-wide mapping and functional genomics approach to elucidating precocious coronary artery disease'.

assistant: **Concept**

A programme is proposed, by an established European consortium, that will exploit advances in complex trait genetics and functional genomics to discover novel susceptibility genes for coronary artery disease (CAD). The aim is to identify novel proteins and pathways implicated in atherosclerosis and arterial thrombosis in order to define new targets for prevention and treatment and to devise diagnostic tools that identify disease mechanisms in individuals. The PROCARDIS programme has assembled a uniquely large and carefully phenotyped collection of subjects with early CAD: >2600 affected sibling pairs; >1300 two generation 'trios'; > 5000 genetically enriched cases; >5000 matched controls free from CAD. A genome-wide linkage screen has been completed, identifying and replicating a novel locus on chromosome 17; genetic association has already been demonstrated within this, and another, locus. The proposed second phase of PROCARDIS will incorporate: a definitive genome-wide association analysis, substantial new investment in bioinformatics and functional genomics platforms (as will be needed to exploit the linkage and association data), and measurement of novel intermediate phenotypes that will yield biomarkers for CAD risk and quantitative traits for genetic analysis. Additional academic and SME partners have been selected to reinforce the existing consortium, each with unique and complementary expertise, to address the needs of post-genome research. PROCARDIS will integrate a critical mass to attain ambitious and clearly defined objectives; by adopting parallel approaches, the PROCARDIS programme can include 'higher risk' components without endangering the overall outcome. The results will address a priority theme, will give impetus to Europe's competitiveness and will s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Young planetesimal belts' to be submitted under Horizon Europe.

assistant: **Abstract**

Recent discoveries of numerous and diverse exoplanetary systems and their debris discs have revolutionized our understanding of how planets and planetesimals form. One of the exciting recent developments is detection of a large number of young systems which appear to be hosting belts of planetesimals, yet also unexpectedly show high amounts of gas. To explain these observations novel computational models must be developed, which take into account all key physical processes shaping the distribution of dust in these systems. I propose to use a kinetic model of collisional evolution of planetesimals and dust, combined with models of dust evolution due to gas drag and radiation pressure, and models of gas structure shaped by viscous evolution and dispersal. To do this I will extend the capabilities of a kinetic model previously used in studies of gas-free debris discs to account for dynamics of small dust grains in the presence of a gaseous disc. This will allow to model the entire range of body sizes, from dust to planetesimals, in a self-consistent way. The project will require knowledge of collisional planetesimal belts as well as of the proto-planetary environment, and this knowledge will be directly drawn from the existing research experience of the candidate. The project will generate a transfer of knowledge to the host institution while developing the candidates theoretical and technical expertise. The results of the project will be of wide use to the planetary science community, as they will help to interpret future observations of young planetary systems, to constrain the process of protoplanetary disc dispersal, and determine properties of dust and gas that may be accreted onto planets in the last stages of their formation.


**Keywords:** protoplanetary discs,  d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Mathematical random graph models for real-world dynamical networks', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Networks are all around us and hugely affect us: the neurons in our brain, COVID-19 spreading through the population, or computer viruses attacking digital infrastructure via computer networks. Experts estimate that in the US alone, their government faced costs over 13.7 billion dollars due to cyberattacks in 2018. Insight into the structure and vulnerability of computer networks can help strengthen our defences against cyberattacks, reducing future cost and disruption. Analysing mathematical models of real-world networks can provide such insight. The abstract level of mathematics also makes such analyses widely applicable in various settings like hacking of computer networks and viral pandemics. Most networks change over time. They grow, shrink, and gain and lose connections, like neural plasticity, friendships made and lost, and computers breaking down. Many mathematical models, however, do not incorporate such realistic dynamics of evolving real-world networks. They only allow for network growth, not for removal of nodes and connections. This creates a gap between the theoretical knowledge and the practical use thereof.I aim to close this gap by analysing properties of two models for real-world networks that incorporate realistic dynamics: Preferential attachment with vertex and edge removal and first-passage percolation on weight-dependent random connection models. The outcomes of this research can influence policy discussions around protecting digital infrastructure and our response to viral pandemics, tying in with the European Commission’s current priorities regarding digitalisation and health within NextGenerationEU. The research through training provided within this fellowship will provide me with leadership skills and more experience in writing grant proposals
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The development of a modular approach to stereocontrolled oligosaccharide synthesis by intramolecular glycosylation' (2002-2006).

assistant: **Concept**

It is now well established that oligosaccharides play fundamental roles in an enormously wide range of important biological processes, including viral and bacterial infectivity, antigenicity and cancer metastasis. In addition it also now recognized that th e post-translational modification of proteins by glycosylation plays a crucial role in successful protein folding, and on the conformation, metabolic stability and catalytic activity of folded glycoproteins. However in the vast majority of cases the functi on of the oligosaccharide is not yet precisely understood, and there is a need for synthetic oligosaccharides in order to elucidate the roles that these oligomers play in their varied environments. Despite impressive recent developments, no synthetic metho dology currently exists that allows the synthesis of oligosaccharides in a reliable and generally applicable manner. The research program we propose will centre on the further development of novel synthetic methodology for construction of synthetic oligosa ccharides, crucially in a totally stereoselective and potentially automatable fashion. The proposal centres on the development of a modular approach to sterecontrolled oligosaccharide synthesis. The crucial point is that whilst neighbouring group participa tion will be employed to give 1,2-trans glycosidic linkages using standard intermolecular glycosylation reactions, that by actually using the same building blocks we shall be able to achieve the stereoselective synthesis of 1,2-cis glycosidic linkages simp ly by performing intramolecular glycosylation reactions. Importantly both sets of reaction conditions will involve the same component steps, but by performing each of these individual steps in a different order we will be able to totally control the stereo c