RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Improving display and rendering technology for virtual environments' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

The aim of this project is to improve lightweight near-to-the-eye displays and tiled stereoscopic large size displays. The improvements on the hardware level consist in developing a unique stereoscopic head mounted display (HMD) using emerging display technology such as OLEDs. For tiled stereoscopic large screen displays improved calibration techniques will be developed to ease and accelerate their use.On the software level improvements comprise the fidelity of the content to be displayed (rendering quality), the interfacing between the user and the displays through innovative 2D/3D interaction techniques for mixed realities and advanced tracking systems. The achievements of IMPROVE are integrated into a collaborative mixed reality product development environment, showcased and evaluated in two application scenarios: collaborative product design in the car industry and architectural design.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'EcoVerse: Carbon-Negative Modular Concrete Blocks for Enhanced Indoor Air Quality and Thermal Comfort - A Comprehensive Experimental and Modeling Approach' (EcoVerse).

assistant: **Innovation**

Conventional thermal insulation materials like mineral wools, polyurethane, and polystyrene foams are widely used in Europe, but their production significantly contributes to CO2 emissions, generating up to 6.9 times CO2. Additionally, these materials impede air circulation in buildings, leading to poor indoor air quality and discomfort. This project seeks to address the need for carbon-neutral or carbon-negative building materials that not only provide thermal insulation but also enhance indoor air quality through effective air filtration. The focus of this research is on developing lightweight indoor concrete blocks utilizing biochar, a carbon-rich material produced through pyrolysis. Biochar can sequester up to 2.6 times its own weight of CO2 while offering exceptional properties such as air filtration, acoustics, and thermal insulation. The project aims to maximize biochar content in concrete blocks to 50 to 75 vol% to achieve superior air filtration and thermal comfort while maintaining adequate mechanical performance. The methodology involves developing granulated biochar aggregates and combining them with low-carbon binders and biochar fines to develop lightweight, carbon-negative concrete blocks. Various mix designs, curing conditions, and additives will be explored to optimize the blocks' physical, mechanical, and durability properties. Advanced analytical techniques, including microstructural studies and multiscale modelling, will be employed to understand and validate the blocks' performance. This project has the potential to significantly advance sustainable building practices by developing a novel material that aligns with EU sustainability goals, the Paris Agreement, and the European Green Deal. By integrating biochar into building materials, this research
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Reprogramming of the leukemic microenvironment by small extracellular vesicles: from characterization to therapeutic application' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The proposed program, to be developed by Dr Pablo Morande, aims at investigating interactions between chronic lymphocytic leukemia (CLL) B-cells and their microenvironment, with a focus on small extracellular vesicles (sEV). CLL is the most frequent hematological malignancy of the adult in Europe. Despite recent advances in the standard of care, there is still no curative therapeutic option. Small EV represent an important part of the cell-to-cell communication. They play a key role in promoting cancer by influencing multiple tumor-related functions like cellular proliferation, migration, and metastasis; and can also impair an efficient anti-tumor immune response. In this proposal, Dr Morande will study the mechanisms underlying sEV-induced cellular modifications in vivo in the context CLL, using transgenic murine models and patient samples. The host group has proved experience in the field of sEV in cancer and recently deepened into the role of sEV in leukemia development in vivo. The candidate will dissect the mechanisms enabling sEV uptake in various types of target cells in vivo, and test inhibitors or neutralizing antibodies to block the pro-tumoral role of sEV in leukemic mice. He will study the functional impact of sEV on the immune system leading to tumor evasion, focusing on immune checkpoint ligands, and design bioengineered sEV to test them as immunotherapy in preclinical models. Finally, he will focus on sEV understudied cargoes such as metabolites by investigating their occurrence on sEV and the consequences on metabolic activity of target cells, to reveal new directions for the development of innovative therapies. The development of the present proposal will enable Dr Morande to achieve a broad range of new technical and management skills through a variety
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Nutrient management legislation in EU countires' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

The purpose of the concerted Action NUMALEG is to get acquainted with the existing and proposed legislations on nutrient management in the different EU countries, to identify the strong and weak points of the various programmes by comparison of these legislations and to identify knowledge gaps of nutrient behaviour in the soil-plant ecosystem. The ultimate aim is to come up with proposals, where possible and where likely to be effective, for more harmonisation in nutrient management legislation between the EU countries. The action will be restricted to nitrogen and phosphorus management, since these are mostly involved in nutrient management legislations in the EU countries. To reach these goals, there is a need for collection of data and for exchange of knowledge to understand the backgrounds of the various legislations. As a necessity to give value to the outcome of the Concerted Action, a book will be published with a complete overview of the current and proposed legislations on nutrient management in all EU countries. Further a report will be written with discussions on the current and proposed legislation and with proposals for harmonisation of this legislation and identification of knowledge gaps. At the end of the Concerted Action NUMALEG, a meeting will be held between the participants and the representatives of authorities of the different countries to explore how the results of the Concerted Action can be distributed and how harmonisation can be implemented. The proposal outlined is consistent with the objectives of sub-area 4.2.1 'Agriculture-Environment Interactions' of the falr-Programme 1994-1998
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Light-induced NanoAssembly' (LiNAss) targeting Seventh Framework.

assistant: **Abstract**

NanoMaterials have huge promise in a wide range of applications of societal importance. Intricate combinations of metals, semiconductors, dielectrics, and molecular components in three-dimensional configurations, have new and unusual properties. Such advanced functions are at the heart of photovoltaics, magnetic and quantum information technologies, photosynthesis, water splitting, electronics, batteries, fuel cells, catalysis and many more crucial areas. Despite much research, we simply cannot yet make such nanomaterials at will. This problem is thus a major challenge for the future decades that we need to solve. The proposal here uses bottom-up assembly of nano-components combined with the application of controlling beams of light, as a new approach to sub-nm precision capable of scale-up.The exact arrangement of nano-sized components can drastically change the optical response of a nanostructure. We directly exploit this optical sensitivity to structure. Irradiation by specific wavelengths of laser light builds up strong optical fields only in parts of the structure which transiently have the right configuration. These regions of high field can be spatially localised to 1nm, far smaller than the wavelength of light. If this induces enhanced binding then optical selection preferentially selects specific morphologies. The principal goal of this proposal is to demonstrate the new strategies for reliable nano-constructs at the 1nm scale, which can be produced in large numbers with essentially identical architecture. Several approaches will be explored in parallel, using the light to either glue together nano building blocks, or to deposit the energy needed to grow nanostructures directly. In addition developing ways for light to flex structures can result in significant
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Endocytic Membrane Compartmentalization by Galectins' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The contribution of clathrin-independent endocytosis to the cellular entry of signaling receptors, cell adhesion factors, and other cell surface molecules is well documented. However, how this process is initiated is still unknown. We have recently found that a cellular lectin, galectin-3 (Gal3), entered cells via morphologically distinct tubular structures, so-called clathrin-independent carriers (CLICs); Gal3 endocytosis was required for the uptake of the CLIC cargo CD44, a cell adhesion/migration factor; CD44 and Gal3 uptake required glycosphingolipids (GSLs); Gal3 induced tubular membrane invaginations in a GSL-dependent manner. Based on these findings we propose the groundbreaking hypothesis that Gal3 is an adaptor that clusters cargo proteins carrying defined carbohydrate modifications together with specific GSLs into nanoscale membrane environments whose mechanical properties drive the clathrin-independent formation of endocytic pits. In this program, we will first establish the compositional topology of endocytic galectin processes (Aim 1). The adaptor hypothesis will then be tested using innovative chemical biology tools (Aim 2). Quantitative models of cargo clustering and membrane shape changes will be developed on the basis of biophysical measurements and coarse grain simulations (Aim 3). Intravital imaging of endocytosis and cell migration in mice will finally explore how the functional link between galectins and GSLs contributes to wound healing in the colon (Aim 4). The molecular functions of galectins and GSLs in endocytosis — major unresolved questions in cellular membrane biology — will thereby be established, providing details from atomic arrangements via multi-molecular complexes and meso-scaled membrane domains to in vivo physiology. I am confident t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Hydrogen at Extreme Conditions: Applying Theory to Experiment for creation, verification and understanding' (HECATE).

assistant: **Innovation**

Hydrogen is the simplest and most abundant element in the universe. It exists under extreme conditions in stars and planets.  Nuclear fusion, requires creating such extreme temperature and pressure on earth.  Lightweight storage of hydrogen in condensed form would unleash its potential as a fuel. The behaviour of a collection of protons and electrons presents an iconic challenge in fundamental physics.Diamond anvil cells (DAC) recently generated pressures above 400GPa, accessing conditions where the mechanical work of compression equals the chemical bonding energy.  Most elements undergo dramatic structural changes in this regime, and rival predictions for hydrogen include molecular and atomic metals, superfluidity, superconductivity and one-dimensional melting.  Yet when the new phase IV was discovered in 2011, it was none of these things: it was a totally unexpected complex molecular insulator. At these conditions experimental data is sparse: we must exploit it to the fullest extent, yet previous theoretical work has concentrated on routine density functional theory (DFT) simulation producing unmeasurable predictions.  I will conduct a programme combining neutron scattering and Raman spectroscopy with theory and simulation focused on measurable quantities.  This will require developing and implementing heuristic theories which do not currently exist.I will develop methods to find free energy, theory to extract Raman frequencies and linewidths from simulation, and techniques to determine the signature from entanglement of quantum rotors.  This requires a thorough re-examination of the quantum scattering processes in the framework of DFT, including the interaction timescale and in metals, and a full quantum treatment of indistinguishable nuclei.Thus HECATE will be uniqu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Importance of regulation mechanisms for the climatic adaptation of tree species (an example of picea abies)' in the context of a Fifth Framework call.

assistant: **Objectives**

Adaptation of Norway spruce to extreme climatic conditions is generally believed to develop in the course of many generations due to the interaction of several evolutionary processes (mostly selection). Recent results with Norway spruce have indicated that climatic adaptation can occur in only one generation in response to the climatic (temperature/photoperiod) conditions during the sexual reproduction. In order to establish the mechanisms underlying this short-term adaptation and to utilise the respective results for practical forestry purposes, several integrated investigations using the same progenies from controlled crosses in different environments are planned. Possible rapid selection processes during reproduction will be analysed by allonyms and DNA markers in female gametophytes and embryos of the different progenies. Possible gene regulations will be analysed by means of new innovative molecular genetic methods aiming at the detection of the mechanisms of potential differential gene expression in different progenies. Both main investigations will be supplemented by phonological and physiological studies on the same Norway spruce progenies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Photochemical cascade reactions by merging organo- and iridium catalysis: A stereocontrolled entry to molecular complexity.' (2014-2020).

assistant: **Innovation**

The requirement for drug discovery to facilitate the identification of successful lead candidates has challenged synthetic chemists to develop innovative strategies to rapidly generate screening collections of chiral molecules. Recently, the application of asymmetric aminocatalysis to cascade reactions has addressed this target enabling extraordinary levels of sophistication and stereocontrol, while fulfilling the requirements for both atom and step economy. Because of the rapid progress achieved, the general perception is that it would be difficult to further expand the synthetic potential of the aminocatalytic cascade approach. However, recent works from the host´s laboratories demonstrate that, by exploiting the photochemical activity of organocatalytic intermediates, light irradiation unlocks reaction pathways unavailable in the ground-state domain. In particular, by bringing a catalytically generated iminium ion to an electronically excited state, it is possible to perform β-functionalisations of enals not achievable under thermal control.This proposal seeks to capitalise upon this novel reactivity to further expand the synthetic potential of the organocatalytic cascade technique, by providing new opportunities for reaction invention. We plan to accomplish this by exploiting the photochemistry of iminium ions in processes that synergistically combine enamine chemistry with transition metal catalysis, thus merging, for the first time, tandem organo-metal catalysis with asymmetric photoreactions. The planned research combines perfectly the host´s expertise in photochemical organocatalysis with the fellow´s experience in transition metal catalysis. These enantioselective cascade reactions will be used for the synthesis of chiral molecules of biological interest. The l
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Robust Automated Driving in Extreme Weather' (ROADVIEW), addressing dissemination and exploitation.

assistant: **Impact**

Complex environment and traffic conditions have major impact on the safety and operations of Connected and Automated Vehicles (CAVs). Weather affects not only the vehicle performance but also the roadway infrastructure, thereby increases the risk of collision and traffic scenarios variations. So far, most automated vehicles have been primarily trained and tested under optimal weather and road conditions with clear visibility. However, the systems will have to prove that they are equally reliable and accurate under any weather and road condition before they can see widespread acceptance and adoption. ROADVIEW integrates a complex in-vehicle system-of-systems able to perform advanced environment and traffic recognition and prediction and determine the appropriate course of action of a CAV in a real-world environment, including harsh weather conditions. ROADVIEW develops an embedded in-vehicle perception and decision-making system based on enhanced sensing, localisation, and improved object/person classification (including vulnerable road users). ROADVIEW ground-breaking innovations are grounded on a cost-effective multisensory setup, sensor noise modelling and filtering, collaborative perception, testing by simulation-assisted methods and integration and demonstration under different scenarios and weather conditions, reaching TRL 7 by the end of the project. ROADVIEW implements the co-programmed European Partnership “Connected, Cooperative and Automated Mobility” (CCAM) partnership by contributing to the development of a more powerful, fail-safe, resilient and weather-aware technologies. The consortium is a perfect combination of leading universities in the field and research institutes, high-tech SMEs, and strong industry leaders. Beyond their research excellence, the co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'European Open Compute Architecture for Powerful Edge' (CAPE) under Horizon Europe.

assistant: **Objectives**

CAPE (European Open Compute Architecture for Powerful Edge) aims to redefine the landscape of edge-cloud computing infrastructures by developing the EdgeMicroDataCenters (EMDC's) and eHPS as a 'new unit of computing' for data-dense edge environments. The project designs and showcase an innovative, open hardware platform that is dynamically composable via CXL to answer the end user needs. EMDC and eHPS provides an open high density platform for heterogeneous computing units (XPU), RISC-V architectures all based on industry-standard form factor, COM-HPC that is supported by a robust ecosystem of Original Equipment Manufacturers (OEMs) within Europe, ensuring wide accessibility and adoption. To allow end users to be digital sovereign e.g. manage the governance of data, AI models, applications deployed across an ‘edge-first’ edge to cloud continuum, CAPE will employ a cloud-agnostic overlay known as Infrastructure from Code (IfC). This innovative approach abstracts the complexities inherent in diverse cloud computing infrastructures and services, empowering software developers to deploy applications effortlessly across the edge-to-cloud continuum. This is achieved without necessitating extensive knowledge of the underlying cloud infrastructure, enabling deployments across on-premise and off-premise, public and private cloud environments with minimal complexity.CAPE's solution will be validated in 3 use cases: the management of intelligent electric energy microgrids, edge AI and satellite communications. All usecases will evaluate RISC-V (EPI) and CXL solutions. Each usecase will be evaluated on technical, economical and sustainability aspects and benchmarked against legacy hardware in local clouds against edge-optimized data centers.


**Keywords:** Digital Sovereignty; Ene