RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Cultivate resilient smart Objects for Sustainable city applicatiOnS' to be submitted under Seventh Framework.

assistant: **Abstract**

In a world of multi-stakeholder information and assets provision on top of millions of real-time interacting and communicating things, COSMOS aims at enhancing the sustainability of smart city applications by allowing IoT based systems to reach their full potential. COSMOS will enable things to evolve and act in a more autonomous way, becoming more reliable and smarter. Things will be able to learn based on others experiences, while situational knowledge acquisition and analysis will make things aware of conditions and events affecting their behaviour. Adaptive selection approaches will manage the uncertainty and volatility introduced due to real-world dynamics. COSMOS will integrate decentralized management mechanisms in IoT based systems allowing applications to exploit millions of things. Socially-enriched coordination will consider the role and participation scheme of things in and across networks. Management decisions and runtime adaptability will be based on things security, trust, administrative, location, relationships, information, and contextual properties. COSMOS will facilitate IoT based systems with end-to-end security and privacy, with hardware-coded security, approaches for security and privacy on storage and with the introduction of an innovative concept, the concept of Privelets for IoT services. COSMOS will deliver data and information management mechanisms to handle the exponentially increasing born digital" data. Extended complex event processing and social media technologies will extract only the valuable knowledge from the information flows, while workload-optimized data object stores will facilitate efficient storage by also exploring the interplay between storage and analytics on networks of data objects. COSMOS enables smart city IoT application
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Community set-up and networking for the reMIXing of online MEDIA fragments'.

assistant: **Concept**

While we have already established, traditional markets for complete videos, e.g. in stock footage portals, media libraries or TV archives, where entire videos may be found and also purchased for re-use in new media production situations, these markets do not permit the easy purchase or sale of smaller fragments of AV materials. The MediaMixer CA will address this deficit by showing the vision of a media fragment market (the MediaMixer) to the European media production, library, TV archive, news production, e-learning and UGC portal industries. We will demonstrate the achievable benefits enabled by the creation, repurposing and reuse of digital contents across borders on the Web, where media fragments are intelligent digital objects, identified and classified at a highly granular degree, integrated with knowledge management, and connected at Web-scale.The objective of MediaMixer is to set up and sustain a community of video producers, hosters, and redistributors who will be supported in the adoption of semantic multimedia technology in their systems and workflows to build a European market for media fragment re-purposing and re-selling. Networking with the community will ensure that research results and technology development truly meets the industry requirements and reflects real world use cases. Demonstrators in media production, news reporting and e-learning will highlight the technology value, with a wider impact achieved through the support of media industry experts and associations to present these results to their members. A number of events will be organised to network the industry members with the research experts of MediaMixer and facilitate technology transfer (by information days and training), and an online portal will drive the geographically distributed co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Functional Proton-Electron Transfer Elements in Biological Energy Conversion' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

Primary energy conversion in nature is powered by highly efficient enzymes that capture chemical or light energy and transduce it into other energy forms. These processes are catalyzed by coupled transfers of protons and electrons (PCET), but their fundamental mechanistic principles are not well understood. In order to obtain a molecular-level understanding of the functional elements powering biological energy conversion processes, we will study the catalytic machinery of one of the largest and most intricate enzymes in mitochondria and bacteria, the respiratory complex I. This gigantic redox-driven proton-pump functions as the entry point for electrons into aerobic respiratory chains, and it employs the energy released from a chemical reduction process to transport protons up to 200 Å away from its active site. Its molecular structure from bacteria and eukaryotes was recently resolved, but the origin of this remarkable action-at-a-distance effect still remains unclear. We employ and develop multi-scale quantum and classical molecular simulation techniques in combination with de novo-protein design methodology to identify and isolate the functional elements that catalyze the long-range PCET reactions in complex I. To fully understand the natural PCET-elements, we will further engineer central parts of this machinery into artificial protein frameworks, with the goal of designing modules for redox-driven proton pumps from first principles. The project aims to establish a fundamental understanding of nature's toolbox of catalytic elements, to elucidate how the complex biochemical environment contributes to the catalytic effects, and to provide blueprints that can guide the design of man-made enzymes for sustainable energy technology.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'PRecursors of ExplosiVes: Additives to Inhibit their use including Liquids' (PREVAIL).

assistant: **Concept**

Homemade explosives (HMEs) are easy to make from readily available materials used for legitimate purposes in everyday life. This availability attracts terrorists to manufacture and use homemade explosives since military and commercial explosives are harder to come by. Two approaches to improve this situation exists. 1) Prohibit or limit the accessibility of these precursor chemicals 2) Use science to solve this problem by making it harder for potential terrorists to make HMEs or by facilitating the detection of these. PREVAIL will address these scientific challenges by a novel approach. The PREVAIL concept and objectives are to prevent the use of hydrogen peroxide (HP) and acetone as precursors to homemade explosives by the development of a series of novel inhibitors, and to ensure that the detection of ammonium nitrate (AN) based devices is facilitated by adding markers tailored to a very sensitive detection system. These objectives must be met without obstructing the legitimate use or causing any adverse effects on the environment or people’s health. The PREVAIL project main activities are development and testing of markers for the inhibition of TATP production and for the concentration of HP by boiling off water (as was done for the London bombings) as well as development of novel markers for easy detection of illicit use of fertilizers. The final outcome of the PREVAIL project are inhibitors for illicit production of TATP and HP based explosives as well as novel marker/detector systems for easy detection of AN based bombs. The PREVAIL project will work together with the chemical manufacturing industry in order to achieve early industrial acceptance of the research. The PREVAIL consortium consists of four research institutes (FOI, TNO,CEA, WIHiE), two chemical indust
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Integrated Opto-Nanomechanical Biosensor for functional Genomic Analysis' under Fifth Framework.

assistant: **Concept**

The aim of this project is to develop a portable biosensor microsystem able to detect hybridisation of nucleic acids with sensitivity to distinguish single base substitutions, deletions and insertions. It will be mainly applied to studies of comparative expression analysis and identification of single nucleotide polymorphisms (SNPs) in human genes candidates to disease.The biosensor microsystem will consist of:i) an array of 20 microcantilevers,ii) an opticaldetection system of the cantilever motion, andiii) a polymer microfluidic system.The hybrid integration of the DNA biochip proposed, in which the array, detector and fluid transport are miniaturized and integrated into a single unit will be the first attempt in the integration of a nanobiodevice.Objectives:The main objective of the Optonanogen proposal is to develop a portable biosensor microsystem able to detect single nucleotide variations in human genes.The biosensor microsystem will consist of:i) an array of 20 microcantilevers produced by standard silicon micromechanical technology,ii) an optical detection system capable of measuring the cantilever movement (lasers and photodetectors).The array of lasers (VSCELs) will be fabricated by Molecular Beam Epitaxy of semiconductor compounds. The array of photodetectors will be integrated with their corresponding amplifier and signal processing circuits, after design and fabrication of the CMOS circuitry andiii) a polymer microfluidic system will be developed for reagents delivery to the biosensor.Work description:The work program, in order to obtain the biosensor microsystem, can be grouped as follows:1. Fabrication of an array of 20 microcantilevers, which will be obtained using standard silicon micromachining technology. The cantilever dimensions will be choose in o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Personalized Cancer Therapy by Model-based Optimal Robust Control Algorithm' (2014-2020).

assistant: **Innovation**

Imagine if tumor growth would be reduced and then kept in a minimal and safe volume in an automated manner and in a personalized way, i.e. cancer drug would be injected using a continuous therapy improving the patient’s quality of life.By control engineering approaches it is possible to create model-based strategies for health problems. Artificial pancreas is an adequate example for this, where by continuous glucose measurement device and insulin pump it is possible to improve diabetes treatment. Gaining expertise from this problem, the current proposal focuses on taming the cancer by developing an engineering-based medical therapy.The interdisciplinary approach focuses on modern robust control algorithm development in order to stop the angiogenesis process (i.e. vascular system development) of the tumor; hence, to stop tumor growth, maintaining it in a minimal, “tamed” form. This breakthrough concept could revitalize cancer treatment. It is the right time to do it as some investigations regarding tumor growth modeling have been already done; now, it should be refined by model identification tools and validated on animal trials. The benefit of robust control was already demonstrated in artificial pancreas; hence, it could be adapted to cancer research. The result could end with a personalized healthcare approach for drug-delivery in cancer, improving quality of life, optimizing drug infusion and minimizing treatment costs. This interdisciplinary approach combines control engineering with mathematics, computer science and medical sciences.As a result, the model-based robust control approach envisage refining the currently existing tumor growth modeling aspects, design an optimal control algorithm and extend it by robust control theory to guarantee its general applicabili
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The organisation of functional microcircuits in visual cortex' under Seventh Framework.

assistant: **Concept**

Determining how the organisation of neural circuitry gives rise to its function has been a major challenge for understanding the neural basis of perception and behaviour. In order to uncover how different regions of the neocortex process sensory information, it is necessary to understand how the pattern and properties of synaptic connections in a specific sensory circuit determine the computations it performs. I propose to establish the relationship between synaptic connectivity and neuronal function in primary visual cortex (V1) with the aim of revealing circuit-level mechanisms of sensory processing. To this end, my laboratory has developed a new method, by which visual response properties of neurons are first characterised with two-photon calcium imaging in vivo, and then synaptic connections between a subset of these neurons are assayed with multiple whole-cell recordings in slices of the same tissue. We will use this method to determine how connectivity, synaptic and intrinsic properties of different excitatory and inhibitory cell types relate to the emergence of their visual receptive fields (RFs). Specifically, we will test the dependence of connections on RF position, structure and other visual response properties, the specificity of connections between simple and complex cells, and the relative contribution of feedforward and recurrent excitation and inhibition towards shaping RFs. Morphological, physiological, connectional and functional data will be used to develop a biophysically realistic network model of this V1 circuit to examine the contribution of different circuit components to single-neuron and network function.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'New generation of low-cost Lateral Flow Assays (LFAs) coupled with paper-based electrical gas sensors: An application study for the rapid determination of Salmonella in food'.

assistant: **Innovation**

Over 420,000 people die each year due to contaminated foodstuffs, with Salmonella identified as one of the key global causes. Yet conventional methods for the determination of Salmonella in food require several enrichment and subculture steps performed by trained staff at lab-based facilities, taking up to 5 days to obtain a result.Lateral Flow Assays (LFAs) have emerged as a powerful alternative method for Salmonella testing because they are rapid, simple-to-use and amenable for Point-of-Need (PoN). However, current LFAs available in the market only provide binary (yes/no) or semiquantitative responses, lacking the rapidness and sensitivity required for food monitoring due to the limitations of the colorimetric transduction.By the integration of paper-based electrical gas sensors (PEGS) as detectors into Lateral Flow Assays, NELLAFLOW will address the challenge of quantitative determination of Salmonella in food without the requirement of long enrichment steps. PEGS have already proven to be highly sensitive towards water-soluble gases determination. They exploit the intrinsic hygroscopic characteristics of cellulose paper and the changes in its ionic conductance in the presence of water-soluble gases. The incorporation of aptamers as biological recognition elements in the PEGS-LFA platform will improve the implementation of the prototype for on-site monitoring as they are low-cost, highly specific, and stable at room temperature. Through a multidisciplinary approach (biomolecular engineering, analytical chemistry, printed electronics, microbiology) NELLAFLOW will tackle a problem in the food industry with an innovative versatile technology that can be easily transferred to other application fields.By combining academic and non-academic training, NELLAFLOW will broaden
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Search for new physics and technological advancements from neutrino experiments at the high intensity frontier. A cooperative Europe - United States - Brazil effort.' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

SENSE promotes the collaboration among European, American and Brazilian researchers involved in the most important research projects in the field of neutrino physics at the high intensity frontier. The observation of neutrino oscillations established a picture consistent with the mixing of three neutrino flavours in three mass eigenstates and small mass differences. Experimental anomalies suggest the existence of sterile neutrino states participating in the mixing and not coupling to the SM gauge bosons. Lepton mixings and massive neutrinos offer a gateway to deviations from the Standard Model in the lepton sector including Charged Lepton Flavour Violation. The FNAL Short-Baseline Neutrino (SBN) program based on three almost identical liquid argon Time Projection Chambers located along the Booster Neutrino Beam offers a compelling opportunity to resolve the anomalies and perform the most sensitive search for sterile neutrinos at the eV mass scale through appearance and disappearance oscillation searches. MicroBooNE, ICARUS and SBND will search for the oscillation signal by comparing the neutrino event spectra measured at different distances from the source. The FNAL SBN program is a major step towards the global effort of the neutrino physics community in realising the Deep Underground Neutrino Experiment (DUNE) which will provide fundamental contribution to the determination of neutrino mass ordering, measurement of CP violation, precision tests of the three-flavor oscillation paradigm using long-baseline flavor transition, search for nucleon decay and study of the burst of neutrinos from core-collapse supernova in the framework of multi-messenger astronomy. SENSE researchers have provided major contributions to the SBN and DUNE projects and will take leading roles in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Jews and Slavs in the Middle Ages:  Interaction and Cross-Fertilization' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The central purpose of this project is to bring down interdisciplinary barriers by showing how the Slavic and the Jewish heritage can each be approached as a unique repository of the unknown texts, traditions, and sensibilities of the other. By focusing on previously unexplored or under-explored medieval texts, I aim to reconstruct the Jewish and Slavic legacies, some of whose materials have been considered lost, while others were misinterpreted or neglected.This research project will resort to historical and philological techniques hitherto considered mutually incompatible in this field. The study intends to use methods of cultural archaeology to explore medieval Judeo-Slavic transparency. By cultural transparency we understand the mutual permeability of different cultures, which facilitates the exchange of ideas and genres of creativity between them. Cultural archeology involves methods of multi-disciplinary research based on the assumption that Eastern Europe constituted a melting pot characterized by an intensive cross-fertilization of cultural legacies. Cultural archaeology studies different historical, religious, and literary texts by looking at them as a palimpsest in which earlier texts and types of discourse come to the fore as shaped by their contemporary socio-cultural settings.The proposed theme has far-reaching methodological implications beyond the Judeo-Slavic cultural realm. This project will build a model of cross-cultural interaction to achieve a better understanding of the situations in which different faith-based ethnic cultures cohabit.