RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The influence of environmental factors on antimicrobial activity of human intestinal defensins' under Seventh Framework.

assistant: **Concept**

Human epithelia are permanently challenged by microorganisms. In the gut, the fraction of strict anaerobic bacteria increases from proximal to distal, reaching 99% of bacterial species in the colon. Moreover, microbial metabolism causes a reduction of the environment to a low redox potential of only –200 mV to –300 mV. Defensins, characterised by three intramolecular disulfide-bridges, are key effector molecules of innate immunity that protect the host from infectious microbes. Human β-defensin 1 (hBD-1) is one of the most prominent peptides of its class but comparison with other defensins suggested only minor antibiotic killing activity. We could recently show that hBD-1 becomes a potent antimicrobial peptide against C. albicans and anaerobic, Gram-positive commensals of the human normal flora in a reducing environment (Nature 2011). The effect was attributable to the linear, reduced hBD-1 peptide.Here we aim to investigate the antimicrobial activity of reduced hBD-1 in more detail. We will study the mechanism of its reduction by cell-culture experiments and in vitro reduction assays. The molecular details of its antibiotic action will be investigated by using bacterial mutants and further in vitro assays. Additionally we aim to characterise the antibiotic spectrum of reduced hBD-1 by using different antimicrobial assays. Also, we plan to systematically test human defensins under reducing conditions and different pH values that occur in the gutBesides we will screen extracts of human intestinal tissue and stool samples for antimicrobial substances by using the conditions described above. Extracts will be purified by HPLC and antimicrobially active fractions will be examined by MALDI-TOF peptide mass fingerprint technique. We hope to identify novel peptides which have b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Development of a telephone headset with voice diminishing technology' (Voico).

assistant: **Innovation**

Voico is developing a noise cancelling technology that will reduce noise created from telephone conversations, and increase the confidentiality of telephone conversations. By implementing a sound cancelling unit in a telephone headset, Voico's technology will reduce the noise from the human voice spreading from the telephone conversation to the surroundings. Thus, those located near the telephone conversation will not be disturbed or be able to hear the conversation's content. In this way, a firms' employees operating in open plan offices will no longer suffer from noise created by their colleagues talking on the phone. By contributing to a better work environment through a lower level of disturbing noise, Voico's technology will help in decreasing stress and exhaustion among employees. Moreover, for those interested in ensuring a private conversation over the telephone, Voico's technology will also fulfil this purpose. The feasibility study concerns reducing technological risk through optimizing and developing a wearable test device for use in pilot tests, as well as development of a business model and a business plan for expanding into the European market.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Harmonised services over heterogeneous mobile, IN and WLAN Infrastructures' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

The main objective of the MobileIN project is to define and develop a novel set of advanced, future-proof, dynamic and configurable harmonised services for the mobile user and worker by taking full advantage of heterogeneous service infrastructures (Intelligent Network Services, Mobile Network Services, VoIP Services). The project builds on operators needs to preserve and enhance existing services infrastructures (IN, CAMEL, LBS), an already major source of revenue, integrated with new, emerging ones (IP, VoIP, SIP etc) that will provide operators and 3rd party application developers with access to as yet unrealised revenue streams.In this context, the project will specify and develop a state-of-the-art open framework for service creation and execution in multi-domain environments that in tandem with open, scalable service access points will realise and demonstrate the developed sophisticated applications in a composite IP-PSTN-PLMN-WLAN environment. The strength and market impact of the envisaged services will emanate from exploiting the full potential of currently dispersed location information, subscriber data, and application logic, that up-to-date cannot be effectively combined by currently deployed schemes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Innovative Training & Decision Support for Emergency operations'.

assistant: **Innovation**

The INDIGO project aims to research, develop and validate an innovative system integrating the latest advances in Virtual Reality, Simulation and Artificial Intelligence in order to homogenise and enhance both the operational preparedness and the management of an actual complex crisis. It will enable: * the 3D interactive and realistic visualisation of the complete crisis environment, including data coming from the field, simulation results, and building interiors. * the simulation of different evolving scenarios for planning, training, and anticipating future states and impending developments during operations, and analyse events after the crisis. * the simultaneous training of decision makers, crisis managers as well as first responders and emergency field units that will be influenced by the simulated scenario and that will reciprocally influence its evolution. * the simultaneous involvement of multiple participants, thanks to its distributed architecture, while offering a unique pictorial way of sharing and communicating complex knowledge across organisation boundaries. In addition, INDIGO will propose a European emergency symbology reference for 2D/3D maps. This will fill an important gap by offering a common visual reference that can be used across Europe to facilitate the immediate and general understanding of the situation, thus improving decision making across organisational boundaries. The definition of the functional specifications of the system will be driven by the analysis of the needs of real end-users participating in the project as partners or involved in the INDIGO User Group. These organisations will test and validate the outcomes of the project with real-world scenarios and multiple emergency organisations. By the end of the project a packaged system
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Building a Decolonized Ethics and Governance Framework for Just and Trustworthy AI in Healthcare' to be submitted under Horizon Europe.

assistant: **Abstract**

Artificial Intelligence (AI) has great potential in healthcare, but it also raises deep ethical concerns as it often discriminates vulnerable groups, amplifying systemic inequalities and preventing equitable access to healthcare. Trustworthy AI is not sufficient to avoid this risk. Bias-free AI systems can indeed still be deeply unjust, if they do not embed social justice principles; and the current ethics and governance frameworks that steer the design, development and use of AI tend to perpetuate forms of injustice both at the local and at the global level. Indeed, they mostly neglect the consideration of perspectives and values other the Western ones, especially those from the Global South (Colonialist AI).JustHealth aims at filling this gap by creating the first doctoral program in the EU and beyond to ensure social justice is adequately considered in the design, development and deployment of AI in healthcare.By integrating ethical, governance, engineering, clinical, and co-creation expertise, JustHealth will: a) elaborate a robust decolonized ethics and governance framework for AI in healthcare and tailor it for 2 paradigmatic use cases involving vulnerable people: freezing of gait (FOG) and rheumatic heart disease (RHD), respectively affecting the older population of Western countries, and the younger population of countries in the Global South; b) test and validate the framework; c) investigate its transferability, also providing insights for sector-specific standards.The framework will contribute to the deployment of just and trustworthy AI systems that can effectively contribute to just healthcare both at local and global level.  JustHealth will offer to 8 DCs an ambitious doctoral programme and exposure to leading EU, South African and US organizations, inc. n
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Comparing the Copperbelt: Political Culture and Knowledge Production in Central Africa', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

This project provides the first comparative historical analysis – local, national and transnational - of the Central African copperbelt. This globally strategic mineral region is central to the history of two nation-states (Zambia and Democratic Republic of Congo (DRC)), as well as wider debates about the role of mineral wealth in development. The project has three interrelated and comparative objectives. First, it will examine the copperbelt as a single region divided by a (post-)colonial border, across which flowed minerals, peoples, and ideas about the relationship between them. Political economy created the circumstances in which distinct political cultures of mining communities developed, but this also involved a process of imagination, drawing on ‘modern’ notions such as national development, but also morally framed ideas about the societies and land from which minerals are extracted. The project will explain the relationship between minerals and African polities, economies, societies and ideas. Second, it will analyse how ‘top-down’ knowledge production processes of Anglo-American and Belgian academies shaped understanding of these societies. Explaining how social scientists imagined and constructed copperbelt society will enable a new understanding of the relationship between mining societies and academic knowledge production. Third, it will explore the interaction between these intellectual constructions and the copperbelt’s political culture, exploring the interchange between academic and popular perceptions. This project will investigate the hypothesis that the resultant understanding of this region is the result of a long unequal interaction of definition and determination between western observers and African participants that has only a partial relationshi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'European Climate Prediction system'.

assistant: **Concept**

The European Climate Prediction system project (EUCP) has four objectives, all directly relevant to the work programme, and fully meet the challenge, scope and impact of the work programme.1. Develop an innovative ensemble climate prediction system based on high-resolution climate models for Europe for the near-term (~1-40years), including improved methods used to characterise uncertainty in climate predictions, regional downscaling, and evaluation against observations. 2. Use the climate prediction system to produce consistent, authoritative and actionable climate information. This information will be co-designed with users to constitute a robust foundation for Europe-wide climate service activities to support climate-related risk assessments and climate change adaptation programmes.3. Demonstrate the value of this climate prediction system through high impact extreme weather events in the near past and near future drawing on convection permitting regional climate models translated into risk information for, and with, targeted end users. 4. Develop, and publish, methodologies, good practice and guidance for producing and using authoritative climate predictions for 1-40year timescale.The system (objective1) will combine initialised climate predictions on the multi-annual timescale with longer-term climate projections and high resolution regional downscaling, using observations for evaluation. Methodologies will be developed to characterise uncertainty and to seamlessly blend the predictions and projections. Users will be engaged through active user groups. The system will be utilised (objective2) with users to co-produce information suitable for European climate service activities. A set of demonstrators will show the value of this information in real-world applications
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'PORTABLE PLATFORM FOR THE ASSESSMENT OF MICROVASCULAR HEALTH IN COVID-19 PATIENTS AT THE INTENSIVE CARE'.

assistant: **Objectives**

As COVID-19 spreads worldwide, the surge in patients requiring intensive care unit (ICU) admission has been overwhelming to the healthcare systems. Critical care triage to allow the rationing of scarce ICU resources is needed but is hindered due to lack of personalization. The management of acute respiratory failure and hemodynamics is critical at the ICU. In fact, of the seven million COVID-19 cases (end of May 2020) 3-12% required mechanical ventilation which forms the primary target of VASCOVID where we focus on;  (1) patient stratification derived from endothelial function evaluation, and, (2) evaluation of cardiopulmonary interactions that personalizes conservative ventilation strategies in order to avoid ventilator-induced lung injury and readiness to wean from the ventilator. VASCOVID will deploy and mature our portable, non-invasive and real-time health monitoring platform for this purpose. This platform combines two bio-photonics technologies, time-resolved near-infrared spectroscopy and diffuse correlation spectroscopy, and is the fruit of long-term collaboration between core project partners in two European projects (BabyLux and LUCA) where high technology readiness level have been achieved for neuro-monitoring and thyroid cancer screening. VASCOVID will adapt the platform to meet the needs of a typical ICU dealing with COVID-19 and other patients requiring ventilation, as well as to leverage large-scale testing of new treatment procedures and therapies aimed to address microvascular impairment and to reduce extubation failure on ICU patients weaning out of mechanical ventilation life-support. The platform is easy to deploy, cost-effective and provides real-time fast results and its transition to clinical practice will be eased through this project by pushing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Reconstructing Late Medieval Quests for Knowledge: Quodlibetal Debates as Precursors of Modern Academic Practice'.

assistant: **Objectives**

ACADEMIA proposes a pioneering study of a neglected corpus of manuscripts stemming from the practice of quodlibetal debates held at Faculties of Arts of European universities, flourishing from the 14th to the early 16th century. As prescribed by the university statutes, dozens of professors participated periodically in these unique collective works of the Middle Ages, which encompassed all the disciplines pursued at the university, from logic to medicine to theology. The PI hypothesises that the professors presented at the hitherto mostly ignored quodlibets their recent scientific innovations, which they then published in the first collective volumes of European academia. The PI thus proposes a novel theoretical framework for understanding the quodlibets: they stand at the origin of the modern concept of science as a collective intellectual enterprise, similar to modern conferences and the subsequent dissemination of results. This makes them and their written form critical for understanding European intellectual and scientific traditions, both past and present. ACADEMIA’s ambition is to establish the corpus of these debates as a new field of study through an extensive examination of manuscripts, thus filling a substantial gap, radically extending the fields of the history of universities and intellectual history, and reconstructing the roots of the modern practice of fostering collective science. A complex analysis of the corpus will bring about a substantial change in our understanding of medieval practices of the production and sharing of knowledge. Aiming to examine the quodlibets as a phenomenon successively interconnecting European intellectual space, ACADEMIA focuses on fourteen universities at which the PI has identified the tradition so far and on their mutual r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'A Co-Evolution Framework for Model Refactoring and Proof Adaptation in Cyber-Physical Systems' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Computers that control physical processes, thus forming so-called cyber-physical systems (CPS), are today pervasively embedded into our lives.Advances in CPSs are the basis for creating environments of smart mobility, smart energy grids, telemedicine, and intelligent manufacturing.These efforts have been identified as important themes on the research agenda of the 7th Framework Programme for Research and Technological Development of the EU.The key challenge in engineering CPSs is the question of how to ensure their correct functioning in order to avoid incorrect control decisions w.r.t. safety requirements.This overall challenge is even more aggravated by the fact that evolution is inherent to engineering CPSs due to incremental development.For example, common practice is to start with a simple CPS model, prove its correctness in a typically laborious process, and incrementally extend the model to better reflect the real-world CPS (i.e., refactor the model while ensuring preservation of safety constraints).In order to address this challenge, especially promising techniques seem to be model-driven engineering to incrementally develop CPSs and formal verification to prove their correctness, together forming the vision of verification-driven engineering.An especially urging research question in verification-driven engineering is how to keep proofs up-to-date when models evolve.The vision of the Sphinx project is to address this question by providing a framework supporting model refactoring and proof adaptation for CPSs, dealing in particular with three research objectives:First, support modeling and refactoring of CPSs, especially w.r.t. an extensible library of semi-automated model refactoring operations.Second, identify an initial set of refactorings and proof adaptation