RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Compact Binaries as Gravitational-Wave Sources' to be submitted under Seventh Framework.

assistant: **Abstract**

We propose a research program to explore the implications of compact binaries, with emphasis on pulsar binaries, for gravitational-wave astronomy. Interest in compact binaries derives not only from an intrinsic motivation of understanding their origin and evolution in various astrophysical environments, but also from the fact that these are strong sources of gravitational waves. Pulsar binaries, one of the prime targets for ground-based gravitational-wave detectors, form a subgroup of compact binaries. This work will involve (a) a comprehensive study on the empirical properties of Galactic pulsar population and (b) a systematic analysis to constrain theoretical models on binary evolution using the empirical rate estimates relevant to pulsar binaries. Establishing the preferred model parameter space will allow us to explore various types of compact binaries with better constraints. This work can be expanded to study statistics of gamma-ray bursts, which are also strong sources of gravitational waves. As one of the short-term projects, we will compare observational properties of gamma-ray bursts with theoretical predictions. This study will provide a unique tool to quantify uncertainties in theoretical assumptions on the formation and evolutionary channels of compact binaries, as well as to calculate more reliable rate estimates for the gravitational wave detection for the current and future detectors.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Bottom-up reconstruction of a Synthetic Erythrocyte'.

assistant: **Concept**

Blood is a precious and vital resource for many clinical interventions. Erythrocytes, its key component, are used to save thousands of lives every day worldwide. Yet, in low- and middle-income countries, its scarcity and unsafe control are endemic burdens that cost lives. In spite of several decades of attempts to develop a safe and universal blood substitute, this goal has yet to be achieved. Beyond the mere transport of gasses, erythrocytes have evolved together with their host organisms to perform very specialized functions. It is now clear that much of their complexity is indispensable to establish effective cardiovascular regulation. Yet, reproducing this complexity in a synthetic, functional facsimile is a challenging endeavour that requires new methods and multidisciplinary approaches. The ambitious goal of SynEry is to reproduce, in an advanced lipid vesicle, the following key features of erythrocytes: adequate lipid asymmetry with raft-like nanodomains; integration of essential functional proteins (both cytosolic and transmembrane) and a biomimetic cytoskeleton (conferring durability, flexibility and biconcavity); enhanced immune tolerability; responsivity to environmental cues (such as under deformation and hypoxia). These goals will be tackled by an interdisciplinary consortium bringing expertise on: droplet-based microfluidics combined with interfacial self-assembly of biofunctionalized nanoparticles (to build complex biomimetic membranes with ordered cytoskeletal nanodomains); DNA origami and self-assembling peptide technologies (to reconstruct a biomimetic cell cortex); and in-vivo testing models (to verify biocompatibility and functionality). The knowledge gained by producing a synthetic erythrocyte, is envisioned to enable the production of artificial ce
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Role of endocycle in Acute Kidney Injury Response and Chronic Kidney Disease development', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Acute kidney injury (AKI) is a global public health concern which results in 1.7 million deaths per year. If not lethal in the acute phase, AKI is considered reversible as suggested by recovery of renal function. However, even mild AKI episodes carry substantial risk of developing subsequent chronic kidney disease (CKD). The pathophysiological basis for this phenomenon remains unclear. Injury and death of tubular cells are recognized as the main factors in the pathogenesis of AKI and functional recovery from AKI was traditionally attributed to the regenerative capacity of tubular epithelial cells (TECs) which are believed to re-enter the cell cycle and repair the damage. Nevertheless, my preliminary data provide evidence that an endocycle-mediated response of remnant TECs may represent a critical mechanism of response to AKI. Endocycles are cell cycle variants consisting of G and S phases alone that repeatedly proceed without cytokinesis and its role in repair of mammalian tissues is mostly unknown and totally unexplored in the kidney. This proposal will be structured into 3 distinct objectives to address: 1. The physiologic relevance of endocycle for kidney function recovery after AKI 2. The role of endocycle in the progression of AKI to CKD; 3. The mechanism by which YAP1 drives endocycle and contributes to CKD development. To this end I will use lineage tracing techniques based on the FUCCI2aR reporter applied in different transgenic animal models of AKI, together with in vitro experiments in human primary cultures of renal tubular cells.Collectively, the outcomes of this proposal are expected to provide an entirely novel view of the kidney’s response to AKI, to further our understanding of the processes that drive CKD following AKI, as well as to describe for the fi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Low Energy Consumption - LEC Greenhouse' (1994-1998).

assistant: **Innovation**

The scientific and technical objectives of this research proposal concern developing a new type of greenhouse with a heat consumption of only 30% of normal consumption in traditionaluninsulated greenhouses. This aim shall be reached through high insulating mobile screens combined with solarenergy stored in rainwater reservoirs. Research is necessary to optimize the Low Energy Consumption LEC greenhouse and to investigate the possibilities of storing solar energy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Colloidal Yielding: tunable glasses to explore plasticity from macroscopic to microscopic length-scales.'.

assistant: **Innovation**

Upon external mechanical loading, amorphous solids initially deform elastically, but for large enough applied stress they may fracture or flow as a plastic fluid. This transition, known as yielding, is one of the most fascinating open problems in condensed matter statistical physics. In fact, the exact nature of the transition is still unclear: some systems show abrupt (brittle) yielding (e.g., in oxide glasses) while others, such soft gels or foams, display ductility with a smooth and gradual increase of plastic deformation. A unique picture of the processes at play is yet missing and recent models and theories claim experimental support. Here I will use a use a novel colloidal glass to explore the yielding transition and its properties. Colloidal glasses are controlled through their volume fraction: it plays the same role of temperature in molecular ones, but it is much more difficult to precisely tune. I will overcome this difficulty exploiting a mixture of nanoparticles and non-colloidal polymer mesogels. The mesogels swell/shrink as a function of temperature, controlling the available ‘free’ volume for the (temperature-insensitive) nanoparticles. This approach allows for an unprecedented precise control of the volume fraction in a colloidal glass without changing particle-particle interaction or their size (e.g., in microgels). The versatility of the system will be exploited to investigate plastic activity for different level of glass equilibration and external applied stresses thanks to cutting-edge experiments involving rheology, time- and space- resolved visible scattering and synchrotron-based X-ray photon correlation. These approaches will be combined to obtain a comprehensive picture of the processes at play, allowing for a ground-breaking study from inter-pa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Reducing the unemployment rate amongst blind people by introducing a working tool that increases their autonomy and productivity.' under Horizon 2020.

assistant: **Concept**

Our objective is to decrease the unemployment rate amongst blind people (75 % in Europe; Source RNIB) by 10 % until 2028 by increasing their autonomy and productivity in the work environment. This is achieved by introducing a tool for blind people that enables the access to any information without the help of others. This is achieved with the Tactonom, a tactile graphics display that is composed of 10.591 tactile points in a DIN A4 sized touch field. Plugged into a PC the tactile display performs the same task as a screen would for a sighted person. The new technology grants blind people instant access to information like tables (Excel), charts, graphs, diagrams, images, maps, forms, graphics, icons, flow charts, mind maps, and many more. For blind people the ability to instantly access such information is no less than a paradigm shift. This is because the currently existing output technologies (single line Braille Displays and Screen Readers) are only able to output text based information. This is insufficient because a vast amount of information is not text based but graphic visualization. However, these are not instantly accessible for blind people today. This diminishes the autonomy and productivity of  blind people and blocks their access to many job profiles.The Tactonom is a disruptive technology for two reasons: 1) it is the only technology that enables the access to all information types.  2) the new patented technology is 5 times cheaper per tactile than its cheapest competitor.Both benefits combined will ensure that the 2.5 M blind and many of the 23.8 M visually impaired people (Source WHO) living in Europe can take active part in society and  will not be left behind by the digital revolution. Also, blind people will be able to access new job profiles which
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'FIC-Mediated Post-Translational Modifications at thePathogen-Host Interface: Elucidating Structure, Function and Role in Infection'.

assistant: **Innovation**

The ubiquitous FIC domain catalyzes post-translational modifications (PTMs) of target proteins; i.e.adenylylation (=AMPylation) and, more rarely, uridylylation and phosphocholination. Fic proteins arethought to play critical roles in intrinsic signaling processes of prokaryotes and eukaryotes; however, asubset encoded by bacterial pathogens is translocated via dedicated secretion systems into the cytoplasm ofmammalian host cells. Some of these host-targeted Fic proteins modify small GTPases leading to collapse ofthe actin cytoskeleton and other drastic cellular changes. Recently, we described a large set of functionallydiverse homologues in pathogens of the genus Bartonella that are required for their “stealth attack” strategyand persistent course of infection [1, 2]. Our preliminary functional analysis of some of these host-targetedFic proteins of Bartonella demonstrated adenylylation activity towards novel host targets (e.g. tubulin andvimentin). Moreover, in addition to the canonical adenylylation activity they may also display a competingkinase activity resulting from altered ATP binding to the FIC active site. Finally, we described a conservedmechanism of FIC active site auto- inhibition that is relieved by a single amino acid exchange [1], thusfacilitating functional analysis of any Fic protein of interest. Despite this recent progress only a few Ficproteins have been functionally characterized to date; our understanding of the functional plasticity of theFIC domain in mediating diverse target PTMs and their specific roles in infection thus remains limited.In this project, we aim to study the vast repertoire of host-targeted Fic proteins of Bartonella to: 1)identify novel target proteins and types of PTMs; 2) study their physiological consequences and molecularmec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Study of Terahertz Focal Plain Arrays' (TFPA) under Seventh Framework.

assistant: **Objectives**

The Terahertz frequency band is largely unexplored both for astronomical and for ground based applications. Over the recent years significant progress has been made in developing coherent detection techniques applicable at these higher frequencies, which enabled the building of array-receivers. When located in a focal plane a telescope such novel systems allow for a manifold increase in performance. However, the development of coherent detector focal plane arrays is still lagging behind. For incoherent bolometric arrays, a novel kinetic inductor detector (KID) has been recently proposed. It makes it possible to multiplex focal plane arrays with many thousands of pixels in very efficient and cost effective way. Backend technologies for both coherent and KID focal plane array will be based on Fourier Transform Spectrometer digital technique, which has demonstrated impressive progress during last few years and ready for large scale arrays. We propose to develop an advanced side band separating mixer technology for focal plane arrays in combination with research directed to increase the operation frequency of superconductor-insulator-superconductor technology by studying new superconducting materials. This research will be combined with development of many kilo pixel KID array. This inter-disciplinary research will enable building large focal plane arrays for use in astronomy and other Terahertz applications.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Ideal Grid for All' (IDE4L), addressing dissemination and exploitation.

assistant: **Impact**

The IDE4L project will define, develop and demonstrate the entire system of distribution network automation, IT systems and applications for active network management. Active distribution networks will utilize distributed energy resources (DERs) for network management including both real time operation and long-term network planning viewpoints. DERs consist of aggregated distributed generation, demand response and other controllable loads.The starting point of development are existing distribution networks, their management systems, future expectations of penetration of renewable energy sources and high expectations of customers for continuity of service. The research and development work done in the project integrates many existing automation and IT systems utilizing available standard protocols in an innovative way and develops new applications based on that system.Demonstrations of integrated automation system and applications will be realized in real life networks in different parts of Europe where are connected large and small scale PV, wind power, heat pumps and EVs located in urban and rural areas. The outcome of the project will be applicable in very near future in all over Europe.Integrated distribution network automation system will be capable of monitoring, controlling, managing fast changing conditions and integrating large number of DERs in distribution network. Technical solutions utilizing the automation system will enhance the reliability of distribution network by improving fault location, isolation and supply restoration, will increase the hosting capacity of distribution network for renewables by managing network congestion with DERs, will optimize the operation of DERs by aggregating DERs and coordinating these with distribution network management, a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'BE-Smart: Innovative Building Envelope for Sustainable, Modular, Aesthetic, Reliable and efficient construction' (Be-Smart) under Horizon 2020.

assistant: **Objectives**

Building integrated photovoltaics (BIPV) provides both essential aspects of substitution of traditional building materials, hence with potential low electricity costs, and high quality architectural design. It has the potential to contribute significantly to clean electricity generation, in line with EU policies, as well as to contribute to the rebuild of a stronger European industrial sector in the field of solar energy.  So far, BIPV has remained mostly limited to emblematic façade and roof demonstration projects with standard modules very often just added on top of an existing finished building. This project will help to break the multiple barriers, which have been holding back the diffusion of BIPV by:  - Supporting the industrialisation of new material and process for the manufacturing of multi-functional BIPV elements, with a focus on break-through transformative approaches to realise, in a cost effective way, aesthetical modules. - Working at improved manufacturing process, allowing the call’s targeted cost reductions, To allow a stronger market deployment of the new technologies, the project will:- Develop a business model and exploitation strategy for each key stakeholders of the whole value chain including for the architectural and building sectors and will enable an improved awareness and coordination among the multiple stakeholders involved in a building/renovation process,- Demonstrate the results of the project through real case spectacular demonstrators and through the implementation of an innovative communication plan dedicated to experts such as architects and builders as well to a large public audience.The unique and multi-disciplinary consortium of BE-Smart, representing the full value chain, will demonstrate cost effective new BIPV product concepts f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Controlling and resolving rotational quantum states in a molecule-surface collision: Matter-wave magnetic interference experiments with ground state molecules.' (2014-2020) under Horizon 2020.

assistant: **Objectives**

The interaction between a molecule and a solid surface is fundamental to a huge variety of research fields and applications, ranging from industrial heterogeneous catalysis and atmospheric chemistry on ice particles, to ultra-cold astrochemical reactions on cosmic dust. One molecular property that is essential for molecule surface interactions, but also particularly difficult to control and resolve, is the orientation & alignment of the rotational axis of the molecule i.e. the quantum rotation projection states. The existing paradigm is that control over this molecular property can be obtained either by photo-excitation schemes and/or by deflecting experiments using strong electric or magnetic fields. Using these approaches valuable insight was obtained, and the crucial role the rotation projection states have on the outcome of molecule-surface collision was demonstrated. However, the two approaches mentioned above can only be applied to a very small sub-group of systems, (typically on excited/paramagnetic species). Here, we propose a completely different approach which utilizes the rotational magnetic moment, which is a general molecular property, to control and resolve the projection rotation states of ground-state molecules. Our matter-wave approach involves passing a molecular beam through a specific series of magnetic fields, where the different wave components interfere and produce Rabi-oscillations characteristic of the molecular wave function before and after scattering. We present proof-of-principle results demonstrating the validity of our general approach, and describe the novel molecular interference and molecular spin echo measurements we will perform to obtain the much-awaited experimental benchmarks in this field.


**Keywords:** molecular beams, magnetic