RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Allele-specific Deconvolution of Tumour DNA Methylation and Expression Data to Reveal Underlying Cell Populations' (DECODE).

assistant: **Concept**

Owing to advances in sequencing technology, we are now beginning to understand the molecular mechanisms underlying cancer development and evolution. Tumours however are heterogeneous, often containing admixed normal cells and different (sub)clones, confounding interpretation of the massive amounts of data flowing from large initiatives such as the International Cancer Genome Consortium.To address this issue, I will develop methods that disentangle tumour bulk gene expression (RNA-Seq) and DNA methylation (Bisulphite-Seq) data to accurately reveal the states of the distinct underlying cell populations. The innovative algorithms will derive estimates of the allele-specific expression/methylation rates and tumour copy number profiles from the data and use them to separate the signal coming from the tumour from that of the normal cells. In a second step, the method leverages the wealth of available cancer ‘omics data using a recommender-system approach to complete the deconvolution. Careful validation will come from teasing apart computationally mixed pure samples as well as from ongoing and planned collaborative single-cell sequencing projects. A detailed analysis of tumour expression and DNA methylation heterogeneity on these single-cell datasets will guide further methodological advances. As an intrinsic part of the project, massive pan-cancer datasets will be deconvoluted. Drawing on the pure transcriptomes and epigenomes, I will construct a more comprehensive taxonomy of cancers, laying the basis for significant improvements in clinical prognostic prediction and personalised treatment.This project will shift the paradigm of genomic tumour heterogeneity to include the more actionable transcriptome and epigenome. In turn this will lead to a better understanding of how (e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Invasive cognitive brain computer interfaces to enhance and restore attention: proof of concept and underlying cortical mechanisms.' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The present project focuses on a barely scratched aspect of invasive cognitive brain-computer interfaces (cBCIs), i.e. closed-loop invasive cBCIs to augment and restore attentional functions. Its aim is to achieve an efficient enhanced cognition protocol both in the healthy brain and in the damaged brain and to study the local and global plasticity mechanisms underlying these effects. The project relies on the unique methodological combination of multi-electrode multisite intracortical recordings and functional magnetic resonance imaging, in association with reversible cortical lesions and intracortical microstimulations, in an experimental model allowing to approach the attentional human function and its dysfunctions to the best. Our goal is to achieve:1. A closed-loop invasive cBCI for augmented attention, by providing the subjects with a feedback on their cortical spatial and feature attention information content as estimated from real-time population decoding procedures, using reinforcement learning, to have them improve this cognitive content, and as a result, improve their overt attentional behavioural performance.2. A closed-loop invasive cBCI for restored attention, by inducing a controlled attentional loss thanks to reversible cortical lesions targeted to key functionally-identified cortical regions and using the closed-loop cBCI to restore attentional performance.3. An invasive cBCI for stimulated attentional functions. We will identify the neuronal population changes leading to a voluntary enhancement of attentional functions as quantified in aim 1 and inject these changes, using complex patterns of microstimulations, mimicking spikes, to enhance or restore attention, in the absence of any active control by the subjects. This project will contribute to the de
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'PROBING REACTION MECHANISMS IN PHOTOCATALYTIC H2 GENERATION' (PREMHYDRO).

assistant: **Innovation**

Anthropogenic climate change, together with increasing demands for energy, requires a drive towards sustainable and renewable energy sources.One solution lies in the advancement of a hydrogen economy, however for this to play a key role, sustainable approaches to producing H2 from renewable energy is required. A promising method for localised H2 production is the direct conversion of solar energy to fuel. Photochemical molecular devices that combine a light-harvesting unit, a bridging ligand and a catalytic center offer considerable opportunities and indeed bimetallic systems have been reported based on such combinations as Re/Co, Ru/Pt, Os/Rh, Ru/Rh, Pt/Co and Ir/Rh. During this research programme the Research Fellow will develop multicomponent arrays based on Ir/Fe and Ir/Co assemblies, and focus on the underlying mechanisms leading to solar hydrogen generation in these catalysts, and investigate structure-activity relationships. The research conducted at DCU (Pryce group) will be complemented by two secondments at Groningen (Browne group), and also to the industrial catalysis partner Catexel.To develop efficient photochemical molecular devices for visible light-driven hydrogen production, a thorough understanding of the photophysical and chemical processes in the photocatalyst is of vital importance. Therefore, to probe the photochemical reaction dynamics, the Fellow will gain experience in time resolved techniques spanning the pico to milli-second time frame, time correlated single photon counting, luminescence, and through secondments (resonance) Raman spectroscopy, TR2 and ns-TR3. During in the secondment to the Netherlands the Fellow will spend a period at Catexel where he will be introduced to the steps in product development and IP management. Unique blend of a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'In the european research area, a thematic network for the shipbuilding technology applied research', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

ERASTAR is intended to promote the joint RTD projects in the European shipbuilding industry. This responsibility is presently carried out by two thematic Networks: CEPS (for the process) and PRODIS (for the products) which are at the end of their contractual existence; ERASTAR will replace them. ERASTAR will, as CEPS and PRODIS, support the activities of ERAMAR, the Thematic Network envelope for all European maritime industries.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Boosting impact generation from research and innovation on integrated freight transport and Logistics system' under Horizon 2020.

assistant: **Concept**

BOOSTLOG Vision is transforming European freight transport and logistics R&I ecosystem to perform optimally boosting impact generation out of R&I investment contributing to i) EU policy objectives  towards climate neutrality, pollution, congestion and noise reduction, free movement of goods, internal security, digital transformation of logistics chains and data sharing logistics ecosystems and ii) companies sustainability and competitiveness generating value for society.BOOSTLOG has identified 4 main areas of action: i) increase visibility and support valorisation of R&I project Results, Outcomes and Implementation Cases in the freight transport and logistics field ii) develope an implement valorization strategies and guidelines to speed up the technological and organisational innovation uptake, including the creation of the Innovation Marketplace and issue recommendations to increase impact of R&I public funding,  iii) Define high potential & priority R&I gaps to make efficient uses of R&I investments and iv) Strengthen R&I impacts communication and Stakeholders engagement in the innovation process.BOOSTLOG will: i) map and assess around 150 EU-funded R&D since FP5 in different freight transport and logistics domains (i.e. the Logistics Clouds), ii) Increase the visibility of projects main results, outputs and potential implementation cases through ALICE Knowledge Platform, iii) develop at least 8 comprehensive and industry actionable reports starting with: a) urban logistics, b) logistics nodes, c) multimodal freight, corridors & transport networks d) freight and logistics data sharing, e) logistics coordination & collaboration, vi) modularization and transhipment to share progress made and highlight the impact achieved through R&I projects, iv) develop valorisation s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Harnessing the potential of Archaea – Training Europe’s next visionaries for an innovative and sustainable future' (ARCTECH) targeting Horizon Europe.

assistant: **Abstract**

Archaea form one of the three domains of life, next to bacteria and eukaryotes. Archaea have unique cellular characteristics that allow them to thrive in extreme environments, for example at high pressures, salt concentrations or temperatures. Although their biochemical and metabolic properties show great potential for a wide range of biotechnological applications, our lack of knowledge about the structure and function of the archaeal cell surface and its role in formation of communities, such as biofilms, is currently hampering the large-scale industrial use of these organisms. Indeed, several prominent questions remain unanswered due to the small scientific community working in the field, and the lack of methods and technologies enabling research under extreme conditions.ARCTECH proposes the first training initiative on archaea, aiming to foster the next generation of European visionaries in ‘fundamental archaeal research and their application in biotechnology’. The 11 Doctoral Candidates (DCs) will address key knowledge gaps and develop methods and technologies for archaeal research, which are needed to unleash the industrial potential that archaea hold. The scientific outcomes of ARCTECH will be applicable to several biotech areas, such as Green Energy production, Sustainable Biomaterials, Biocorrosion, Enzyme production and Drug Delivery.This project will directly impact the European Higher Education Sector as the first research training initiative embarking into the unchartered world of archaea. The DCs will be trained by world experts from European academic and industrial institutions, benefiting from strong interdisciplinary exposure (e.g. microbiology, bioimaging, biogas production). These entrepreneurial, innovative, and resilient DCs will be of great value bo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Solar Dinitrogen Activation'.

assistant: **Concept**

SolarAct aims at a fundamental theoretical understanding of transition metal catalysts that mediate the photochemical bond cleavage of the dinitrogen molecule. The efficient activation of dinitrogen (N2) as an abundant and thus very cheap resource is a promising target for the development of sustainable chemistry, e.g. to produce NH3 as a “solar fuel” or synthesize value-added products relevant for chemical industry. A new approach in N2 activation is the photolytic N-N bond cleavage in linear M-N-N-M complexes, for which five synthetic examples are known. However, the dynamical processes inducing N-N cleavage in these complexes after light excitation are not understood at a molecular level. SolarAct is the first research project to unravel the working principles of the existing N2 photoactivation catalysts using a combination of ab initio excited state dynamics simulations and multiconfigurational quantum chemistry methods. The project will push the boundaries of excited state dynamics simulations and provide a proof of principle for their application to dimeric transition metal complexes with demanding electronic structures. The key requirements for N2 photocleavage will be rationalized by systematic in silico variations of the known systems, culminating in improved N2 photoactivation catalysts according to a design target formulated for SolarAct. The researcher will transfer expertise in computational transition metal chemistry and theoretical spectroscopy to the host group and will gain expertise in novel methods for static and dynamic chemistry problems. A cross-sectorial and interdisciplinary workshop will increase the researcher's and host's networks. The researcher will emerge from SolarAct fully qualified for an independent career, including a unique, highly co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The evolutionary origins and consequences of human-commensalism in Passer sparrows' (EVOSPARROW).

assistant: **Concept**

Human-commensal species are almost constantly present in our daily lives; they are the mice in our fields or the sparrows in our gardens. The evolutionary trajectories of these species are intertwined with our own through the development of agriculture and human civilization, yet we know surprisingly little about their origins. My project, EVOSPARROW, will focus on Passer sparrows, including the House sparrow, one of the most ubiquitous commensal species. I will first use whole-genome resequencing to resolve the phylogeny of the Passer genus and provide context for the evolution of human commensalism. I will then make use of genomic data from over 120 individuals from across the Passer distribution to reconstruct the recent evolutionary history of sparrows in Europe. I will use coalescent models to test whether House sparrow migration into Europe is consistent with the introduction of agriculture during the Neolithic.The consequences of commensal relationships have rarely been studied in an evolutionary context.  Yet comparisons between commensal and non-commensal lineages offer a means to understand the phenotypic and genetic basis of adaptation to human modified niches. I will quantify behavioural and morphological phenotypes between commensal House sparrow populations and a non-commensal House sparrow lineage occurring in the Near East, as well as other non-commensal Passer species. I will then scan the genome to identify the genetic basis of these phenotypes and quantify their segregation in the wild.With EVOSPARROW, I will develop an evolutionary framework to study how, when and dependency on the human niche arose in commensal species. Passer sparrows are the ideal system for this aim and with high-resolution genomic data, it is now possible to answer these questio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'DEvelopment of advanced LASer based technologies for the manufacturing of TItanium HLFC structures'.

assistant: **Concept**

World air traffic volume is expected to grow per 2 in the next 15 years and that is the reason why reduction of air transport contribution to climate change is nowadays one of the most important objectives for aircraft manufacturers. The reduction of environmental impact requires a continuous improvement in aircraft efficiency, which depends on the use of lightweight structures and efficient aerodynamics, among others. Hybrid Laminar Flow (HLFC) on wing and fin is one of the potential ways to enhance the efficiency of the aircraft and to achieve up to 10% of fuel saving in commercial passenger aircrafts. A design approach for HLFC structure is made of a perforated skin sheet which is stiffened by stringers. This structure is produced by joining parallel aligned stringers to laser micro-drilled thin skin. Afterwards, a straightening process is necessary to achieve the flatness requirements. DELASTI project aims at i) the development of process and ii) system technology for reproducible laser welding and straightening of large titanium panels for HLFC structures, iii) assisted by a FE-based procedure focused on the prediction of 3D deformation and residual stresses. A revolutionary approach is sought which implies the use of one laser source as the only production means, in order to get the whole process in a single production stage. In this context, the present project pursues the following technical objectives:• Development of welding and straightening processes and system up to TRL 6, in order to obtain structures with sound joints and adequate flatness, in challenging large-scale thin (0.8 mm) structures• Integration of seam tracking and development of on-line process surveillance system• Accurate and fast prediction of distortion and residual stress for the whole pro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Intangible Assets and Regional Economic Growth' to be submitted under Seventh Framework.

assistant: **Abstract**

The objective of IAREG is to analyse the role played by intangible assets (IA) in the generation of innovation, competitiveness and consequently economic growth and increases in productivity at regional level with a special emphasis on the geographical space in which such processes occur. The specific objectives of the project will be: To develop new indicators for improving the measuring of some of the IA that we consider to have the most influence in the generation of economic development. To analyse how IA and their interaction define the environment affecting firms’ location. To measure the role of regional externalities in the generation of IA and in determining local economic performances in Europe and in the diffusion of knowledge. To provide decision makers with policy recommendations in order to support them in the future design and implementation of regional innovation strategies. The main result expected in the project is the guide of policy recommendations and the dissemination of this guide among regional, national and European policy makers. The project will be carried out by a consortium of 11 partners from 9 European countries. To ensure the achievement of the proposed objectives, the project is structured in 8 workpackages. The first block of workpackages, comprised by WP1, WP2 and WP3 will research on the impact of different intangible assets on innovation, regional economic growth and productivity, both at a theoretical but especially at the empirical level. WP4 and WP5 will analyse the role of spatial knowledge flows (knowledge diffusion) as a transmission mechanism from IA to innovation and growth. WP6 will be devoted to the development of a guide of policy recommendations for stimulating intangible investment and economic growth. WP7 will focus