RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Ninth symposium on neutron dosimetry-advances in nuclear particle dosimetry for radiation protection and medicine' (NEUDOS), addressing dissemination and exploitation.

assistant: **Impact**

Eight Neutron Dosimetry Symposia have been organised in Europe. EURADOS considered it timely to initiate the Ninth Symposium, since the eighth one was held in 1995. Delft University of Technology was selected to organise the Ninth Symposium. This symposium will provide an opportunity for considering developments in neutron dosimetry and its application in radiation protection and radiotherapy. The symposium also provides the possibility for presenting new information related to future developments. The programming will include sessions covering various aspects of current research on neutron dosimetry introduced by invited speakers.It will also allow presentation of recent developments by international bodies such as the ICRU. It aims to bring together those involved in research, health physicists, regulators and representatives of international advisory bodies.The symposium will provide a forum for considering developments particularly in neutron (and nuclear particle) dosimetry for radiation protection, radiobiology and therapy. This is especially important since the most recent symposium was held in 1995 and interest in neutron dosimetry continued since then, e.g. recently, the ICRU published a Report on determination of dose equivalent quantities for neutrons. Other areas of increasing interest are aircrew and space dosimetry and computational dosimetry. The Symposium will also provide a forum for representatives of regulatory organisations and industry to discuss their needs and for the current work of ICRU and other bodies in this area to be presented and discussed. Invited speakers will give state-of-the-art presentations covering key aspects of current work, and research scientists will present proffered papers and posters. The proceedings will be published in an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Relationship between homologous recombination and transcription - the role of chromatin structure' (1994-1998).

assistant: **Innovation**

The study of recombination between repeated sequences makes possible to understand the processes involved in the generation of deletions and other chromosomal rearrangements.  The cellular functions that stabilize the genome by avoiding recombination between repeated sequences are being identified in Saccharomyces cerevisiae. Hprl, Hrsl and Hrs2 are proteins involved in this stabilization that also play an important role in transcription. They are functionally located at a crossover point between recombination and transcription, likely because they play a role in an element required for both processes. The main objective of this project is to elucidate if this common element is chromatin structure. We plan to carry out 1. A biochemical characterization of Hprl, Hrsl and Hrs2. 2. An analysis of the influence of hprl, hrsl and hrs2 mutations on chromatin structure. 3. A chromatin-structure analysis of the DNA sequences that are able to initiate homologous recombination in yeast. 4. The initial steps to isolate the elements involved in stabilization of genomic repeated sequences in animals.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The management control of innovation: the role of management control technologies in the offshoring of R&D processes' to be submitted under Seventh Framework.

assistant: **Abstract**

The recent research stream on the role of accounting and management control systems in innovation settings, focuses on the difference between control systems which foster innovation and those that foster productivity. It seeks to find the patterns of effects of formal and informal control systems and helps to unravel the correlates of control systems on innovation. This research project aims at contributing to the understanding of innovation processes as practices by inquiring how elements of various control systems engage in the development of innovation and how the interconnections between different technologies of managing, which intervene in the shaping of innovation practices, could be more important than their separation. The ambition of this research project is to inquire into the role that these management technologies, as ‘mediating instruments’ between arenas and actors, have in the generation and diffusion of innovation and thus in the process of making and constructing of markets. These issues are investigated in two European multinational organizations which are experiencing the offshoring of R&D processes. Offshoring of R&D activities is a way of exploiting trans-national synergies and co-operation in order to foster innovation and it is of particular relevance for innovation management and management accounting studies because it raises the issue of controlling innovation at a distance by managing inter-organizational networks which are characterized by a high geographic dispersion. In these social arenas accounting and management control technologies mediate and transform uncertainties linked to innovation development and shape networks which develop across time and space. The research is inter-disciplinary and based on the use of sociological theories a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The Para-T System  A quick blood group device to match in situ the donor bag and the receptor arm during a blood transfusion, avoiding major incompatible errors.' under Horizon 2020.

assistant: **Concept**

The Para-T System ""A quick blood group device to match in situ the donor bag and the receptor arm during a blood transfusion, avoiding major incompatible errors"". The Para-T system is a double identifier device (two plastic cassettes) designed on the one side, to be attached to a bag containing whole blood or Red Blood Cells and on the other, to the catheter inserted in the patient vein allowing a direct, quick (less than a minute) and permanent blood group identification (ABO typing).The ABO tests in the bag and in the patient’ catheter is kept visible from the donation moment till the end of the patient hospitalization, allowing a visual comparison of the blood groups between both cassettes and detecting labelling errors. The technology reduces 4 ABO re-checking during the blood component processing (from a total of 7) reducing staff costs. Combining bag and patient cassettes, the Para-T system conforms a Transfusional Safety System that prevent ABO incompatible transfusions by means of a visual checking (simple solution) or using a PDA QR code reader that controls a solenoid valve incorporated in the tubing system to prevent automatically the transfusion if both bloods are incompatible (complex solution).  The performance of the proposed Safety System is as efficient to avoid mistakes as the most advanced electronic solutions based on personalized wristbands and a sophisticated supportive software offered by some large pharmaceutical firms, but at one tenth of the cost. The market applications for the new Transfusional Safety Solution are huge as many developing and developed countries cannot afford the expensive electronic solutions and Para-T brings a cheap option to the marketplace with equal or even superior performance.    ""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Precision Particle Physics from extreme ASTROphysical transients'.

assistant: **Concept**

Supernovae (SNe) and neutron star mergers (NSMs) host matter in extreme conditions, exhibiting processes, within the Standard Model (SM) and beyond it (BSM), not testable on Earth. The hot, dense cores of these objects are factories of BSM particles, such as axions, sterile neutrinos, and millicharged particles (MCPs). BSM particles emission may alter the duration of the neutrino burst observed from the historical SN 1987A, but the seminal studies are based on outdated SN simulations. BSM particle emission would also have produced a characteristic gamma-ray burst concurrent with the NSM GW 170817, potentially constraining multiple BSM models, including sterile neutrinos and MCPs, for which no investigation exists. Further, self-interactions in the BSM sector, predicted for many dark matter (DM) candidates but neglected in historical studies, can alter the nature of the BSM outflow. This action will provide a unified answer to these shortcomings, reassessing SN bounds on BSM particle emission using updated SN simulations, including the impact of potential self-interactions, and extending the use of NSMs as a probe of BSM particles. Further, the dense neutrino outflows are sizably affected by neutrino self-interactions. Even SM weak interactions trigger collective flavor conversions, whose outcome is only recently being cleared up. Secret neutrino self-interactions, stronger than the weak ones, can alter both the neutrino light curve and flavor conversions. We will consider this impact to potentially draw constraints on secret neutrino interactions.


**Keywords:** Light particles beyond the Standard Model, supernovae, neutron star mergers, axions, dark matter
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'A new concept for the hardening of polymers allowing the production of disposable surgical blades preventing the need for sterilisation (DISBLADE)' in the context of a Sixth Framework call.

assistant: **Objectives**

The economic objective of our work is to enable the partners and the estimated 10 licences to Displace at least 0.1 % of the ?9.8 billion per annum of imported medical technology and devices. Substitute into at least 0.20/% of the European market of ?39 billion p.a. for existing medical technology and devices and 0.04% by 2012. Provide at least ?6.324 million p.a. of automated, disposable surgical blade manufacturing cells. The technological objective of our work is to produce a process for the manufacture of disposable polymer surgical blades that achieves a polymer blade with a surface hardness of at least 7 Mohs'. Achi,eves a blade surface hardness of at least 5 Mohs' to a depth of at least 15 microns. Achieves blade stiffness comparable to existing stainless steel blades Has the ability to produce a blade that can be cost effectively sharpened to a level of sharpness comparable to existing stainless steel blades and conform to the relevant sections in BS 2982:1992, Achieves a hot plate disposal route that renders the blade sharp safe in less than 1 second. A polymer scalpel will be designed using finite element analysis (FEA) to model the blade stiffness and rapid prototyping techniques to verify ""feel"" and ergonomics. A prototype two shot injection moulding tool with an innovative injection compression feature on the blade cavity to ensure sharpness will be designed and manufactured. The resultant polymer blades will be surface hardened using ScCOz to plasticize the outer layers of the polymer and innovative Sol-Gel chemistry will be used to increase surface hardness. The resultant blades will be tested for blade hardness and stiffness. A grinding and polishing system will be developed to obtain a blade sharpness comparable to existing stainless steel blades. The
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Training network on functional genomics and proteomics of arabidopsis ubiquitin ligases and their targets in signalling' in the context of a Fifth Framework call.

assistant: **Objectives**

After completion of yeast, Arabidopsis, Caenorhabditis, Drosophila and human genome sequences, the next challenging task of biology is to identify the functions of eukaryotic genes and their protein products, which is a prerequisite for future biotechnological applications. Building upon its traditional agricultural links, plant research can now deploy new research tools to functionally characterise the Arabidopsis and rice genomes using proteomics and functional genomics. As the function of genes is ultimately controlled by the stability of their protein products, a central target is to understand how the ubiquitination-dependent proteolysis pathways regulate the stability of proteins. In these pathways, E3 ubiquitin ligases SCF (Skp1-cullin-F-box protein) and APC/C (anaphase promoting complex) are essential to control the stability of regulatory factors involved in signal transduction, transcription and cell division. Due to applications in cancer biology, the study SCF and APC/C is a focus of intense current research. In Arabidopsis, about 2.5% of all proteins represent SCF and APC/C components suggesting that SCF and APC/C mediated proteolysis represents also a central regulatory pathway in plants. The goal of this proposal is to gain a generally applicable information about the function and regulation of conserved components of plant SCF and APC/C complexes. To reach this goal, a network will unite interdisciplinary expertise to study the composition and substrates of SCF and APC/C complexes using protein interaction, biochemical, mass spectrometry, physical and immunological techniques, reverse genetics, transcript profiling and high-through-put genetic engineering. The project aims to reach a break-through in our understanding of the role played by plant SCF and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'PYrolysis of biomass by concentrated SOLar pOwer' under Horizon Europe.

assistant: **Concept**

PYSOLO (PYrolysis of biomass by concentrated SOLar pOwer) project aims at preparing the ground for a novel groundbreaking and fully renewable process combining concentrated solar power and biomass pyrolysis. Thanks to the use of solar heat in the pyrolysis process, the production of valuable products bio-oil, biochar and pyrogas can be maximized and the associated CO2 emission minimized, with economic and environmental benefits compared to conventional pyrolysis. The proposed system uses particles heat carrier, ensuring operational flexibility and avoiding the need of heat transfer surface in the pyrolysis reactor that facilitates the system scale-up.  Specifically, PYSOLO process aims at developing at TRL4 the two key unit operations of this novel solar pyrolysis system, namely: (i) the solar particle receiver and (ii) the pyrolysis reactor with the associated particle-char separator. The very innovative feature of PYSOLO lies in its innovative and unique coupling of pyrolysis technology with high temperature CSP system. This ground-breaking feature can potentially offer the following main advantages: - delivering solar bio-oil, electricity or pyrogas and biochar for many energy and non-energy uses, when solar energy supplies the heat necessary for the pyrolysis process, either in sunny hours or by exploiting high temperature stored solids; - run in self-mode the pyrolysis process (i.e. with electric heating or burning pyrogas and biochar), when solar energy is not sufficient and the TES unit is discharged; - providing balancing services to the electric grid: 1. from the conversion of the available pyrogas when solar energy or TES are sufficient to maintain the pyrolysis process running and the grid requires the generation of additional electric power; 2. by using low-
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Real-time biomarker detection systems for rapid medical decision-making in cancer and cardiac diseases'.

assistant: **Innovation**

RealCare is a cutting-edge research initiative focused on developing and validating next-generation point-of-care (PoC) systems that detect essential biomarkers in human biofluids in real-time. These systems are designed to be compact, energy-efficient, and integrated with extended reality interfaces, with a specific emphasis on cancer and cardiac diseases in demanding clinical settings. RealCare's approach includes advanced biomarker detection technologies, such as microfluidics and new generations of microneedles, label-free electrochemical biosensors using 2D materials, optical sensors utilizing CRISPR, biological amplifiers combined with fluorescent microscopy, and scalable SPR with energy-efficient electronic readouts, AI data processing, and wireless communication units. Additionally, RealCare will design portable, interoperable, and adaptable PoC systems that integrate the biomarker detection technology with vital sign monitoring, including advanced data analytics and AI methods. The initiative also focuses on developing intuitive extended reality interfaces, such as augmented and virtual reality, to visualize biomarker data in real-time and facilitate rapid medical decision-making in integrated in-care environments and workflows. Rigorous clinical validation studies will be conducted in relevant clinical settings, including the surgery room, ICU, and patient's home, to ensure accuracy, reliability, usability, and impact on patient outcomes.RealCare places special attention on including a diverse patient population in their studies to validate the effectiveness of the developed systems. Data quality, interoperability, and medical data protection are key considerations in RealCare's strategy. Based on our unique PoC technological platform and our strong, multidisc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Real-time, in-situ, N, P, K, pH and electrical conductivity soil-analysis system to facilitate accurate nutrient management' (NUTRI-STAT).

assistant: **Concept**

Nutri-Stat addresses the need of SMEPs with a cost-effective and real-time soil nutrient sensing system using ISEs integrated in an LTCC based micro Total Analysis System. The technological device will be composed of a complex soil probe combined with a data-logger for the measurement and recording of the concentration of the macronutrients Nitrogen (N), Phosphorus (P) and Potassium (K) present in the soil. Nutri-Stat will also read electrical conductivity and pH levels in soil.The Nutri-Stat system shall also feature user-friendly software to assist in soil nutrient management. The positive impacts of this tool will contribute to environmental and financial sustainability, whilst significantly improving the quality standards of agricultural produce across the EU.Nutri-Stat will provide farmers with constant monitoring of fields, tailored crop analysis and disease management, making information on the nutrient status of arable land for the first time ever, easily accessible and available to the farmer anytime anywhere.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Surveillance and control of microbiological stability in drinking water distribution networks (SAFER)' under Fifth Framework.

assistant: **Concept**

Drinking water meeting microbiological standards appears to be a significance source of gastrointestinal illnesses. Such an endemic situation can be related to the constant introduction of low level of pathogens and growth of heterotrophic microorganisms in the distribution system bio films. The control of biological stability of drinking water during its transport in distribution systems is an actual challenge in terms of public health that requests sensitive and rapid analytical tools. On line, non-destructive techniques for early measurement of bio film accumulation, detection of pathogens in bio films, and rapid evaluation of the disinfections efficiency represent the main objectives of the programme. All industrial sectors or institutions using water are concerned by the development of such techniques.