RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'SMS - Safety Micro Sensor' (SMS).

assistant: **Concept**

Objective of the Safety MicroSensor (SMS) project is to leverage on an innovative and versatile microelectronics platform (codenamed SENSIPLUS) in development at Sensichips, currently at its 3rd iteration, that enables integration of sensors with CMOS microelectronics into a single miniature CBRN-E sensor chip of only 3x3mm. SENSIPLUS is currently being customized for the detection of hazardous chemicals by combining with the chip nanomaterials sensitive to a number Toxic Industrial Chemicals (TIC) and deadly Chemical Warfare Agents (CWA) such Sarin and Tabun. One chip can host up to 12 different sensors and it can connect to up 4 external sensing elements or detectors. The same chip will be interfaced to an external solid state Radiation Detector (i.e. a CZT or CdTe) for the concurrent monitoring of illicit radiation sources. The resulting device, the most miniaturized, low power and low cost yet on the market, will be configured into Smart Cables.The single chip CBRNE microsensor, when instantiated into smart cables, is the basis to build easy to install and to operate continuous monitoring of critical infrastructures or scanning portals of high passage area and for use at occasional crowds gatherings. The same chip has also been designed to be included into smartphones and most other wearable devices for which it is already been demonstrated.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Role of cell membrane associated Hsp70 in cancer cell adhesion and metastasis'.

assistant: **Innovation**

We propose an interdisciplinary project at the interface of biophysics, biochemistry, and medical research. Our objective is to investigate the specific role of cell membrane associated heat shock protein 70 (Hsp70) in the context of invasive cancer. In particular we address the question how cell membrane localization of Hsp70 affects differential adhesion of cancer cells and the formation of metastasis. In general, heat shock proteins (HSP) assist in folding of nascent proteins, prevent protein aggregation, and assist transport of proteins.  Upon a variety of stresses HSP production is rapidly upregulated. Hsp70 is the major stress-inducible member of the HSP70 family. In normal cells it copes with harmful unfolded and denatured protein conferring protection to the cell. Tumor cells frequently present Hsp70 on their outer surface where it exhibits additional activities. For a number of different tumors a high level of membrane Hsp70 has been found to indicate drastically decreased survival chances in patients. Moreover it has been implicated in formation of metastasis where it might support spread and anchoring into distant tissues. These findings highlight the clinical significance of cell membrane associated Hsp70 and the need for a better understanding of its role in differential cell adhesion and progression of cancer.  We will employ atomic force microscopy (AFM) in order to elucidate the function of membrane Hsp70 as a possible adhesion molecule or mediator of cellular adhesion. (1) Using single-cell force spectroscopy we will characterize and quantify adhesion forces of Hsp70 positive and negative cells to different substrates mimicking their interaction with extracellular matrix and host tissue. (2) With the help of a specialized AFM technique that enables topo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Comparison of heat transport physics in plasmas with and without internal transport barriers in the tokamak ASDEX Upgrade' (1998-2002).

assistant: **Innovation**

The objectives of the project are to study the heat transport in fusion plasmas with and without internal transport barriers. This will be performed in the tokamak ASDEX Upgrade in steady-state and also using power modulation of the electron heating. First, heat transport in conventional scenarios (without transport barriers) with dominant ion heating will be addressed. This will extend the studies made so far in plasmas with dominant electron heating. Data analysis by power balance and interpretation of the heat pulse propagation will yield important results on the properties of electron transport with heated ions. Comparison with first-principle transport modelling is expected to improve the insight into the underlying transport physics. This basis should be used to investigate the more complicated case of plasmas with internal transport barriers.The same techniques and similar analyses will be applied.Modelling using the same physics basis in which turbulence is suppressed or reduced will be applied. From this consistent approach we expect to improve the picture of heat transport in such plasmas, which is essential for improving the prediction of the performance of a next step device such as ITER. In this project the applicant will acquire experience of working in a large group and in a complex experimental environment. The project has a multidisciplinary component giving the applicant the opportunity to address different aspects of plasma physics, contributing therefore to broadening of his knowledge and experience, He will be responsible for designing the dedicated experiments and for carrying out the analysis in collaboration with his colleagues. The host institution expects from the applicant a significant contribution on this important field of research. The app
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Ultrasmall Chemical Imaging of Cells and Vesicular Release'.

assistant: **Objectives**

The long-term goal of this research is to establish the chain of molecular events associated with (1) neurotransmitter release at the single cell and subcellular level and (2) with cell differentiation and reprogramming. These are incredibly important goals for which there are few analytical chemistry methods that are available and useful. The immediate goal therefore includes development of three chemical methodologies at the cutting edge of analytical chemistry: 1) the development of arrays of nanometer electrodes that can be used to spatially measure the release of easily oxidized substances across the cell surface; 2) to improve the combination of MALDI and cluster SIMS ion sources on an orthogonal QStar instrument to enable protein and glycoprotein analysis at the single whole cell level, lipid domain analysis at the subcellular level, and importantly, depth profiling; and 3) the application of information discovered at single cells and of the methods developed in goals 1 and 2 to an in vitro model of cell-to-cell communication and regeneration. I intend to build on my expertise in both electrochemistry and SIMS imaging to develop these approaches. The work described here constitutes two new directions of research in my group as well as new analytical chemistry, and, if successful, will lead to researchers being able to gather incredibly important new data about cell-to-cell communication and cell differentiation and reprogramming as well as to a better understanding the role of lipids in exocytosis and endocytosis.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Precision confiner for mechanical cell activation' (ACTICELL) under Horizon 2020.

assistant: **Objectives**

In tissues, cells have their physical space constrained by neighbouring cells and extracellular matrix. In the PROMICO ERC project, our team proposed to specifically address the effect of physical confinement on normal and cancer cells that are dividing and migrating, using new pathophysiologically relevant in vitro approaches based on innovative micro-fabrication techniques. One of the devices we developed was meant to quantitatively control two key parameters of the cell environment: its geometry and its surface chemical properties. The main technical breakthrough was achieved using micro-fabricated elastomeric structures bound to a hard substrate (Le Berre Integrative Biology, 2012). The method led to important fundamental discoveries in cell biology (Lancaster Dev Cell 2013, Le Berre PRL 2013, Liu Cell 2015, Raab Science 2016). In part based on our findings, the notion that confinement is a crucial parameter for cell physiology has spread through the cell biology. Based on this, our idea is that cell confinement could be used as a powerfull cell conditioning technology, to change the cell state and offer new opportunities for fundamental research in cell biology, but also in cell therapies and drug screening. However, our current method to confine cells is not adapted to large scale cell conditioning applications, because the throughput and reliability of the device is still too low and because the recovery of cells after confinement remain poorly controlled. It is thus now timely to develop a robust and versatile cell confiner adapted to use in any cell biology lab, in academy and in industry, with no prior experience in micro-fabrication. Achieving this goal involves a complete change of technology compared to the ‘homemade’ PDMS device we have been using so far.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Novel hybrid thermoelectric photovoltaic devices: modeling, development, and characterization' under Horizon 2020.

assistant: **Concept**

This project aims at the practical realization, the characterization, and the industrial/commercial evaluation of optimized hybrid thermoelectric-photovoltaic (HTEPV) devices. HTEPV devices can convert the solar energy more efficiently than normal solar cells, since the thermoelectric component recovers part of the unused heat generated within them. In this project the hybrid optimization will be obtained with an innovative approach recently proposed within a theoretical/computational study by the fellow, Dr. Bruno Lorenzi. The principal objective of this action will be the practical hybridization of two kinds of single junction solar cells in HTEPV devices achieving performances higher than the PV cell alone by at least 25%. The project will be organized in three main phases: outgoing phase (first HTEPV development), ingoing phase (second HTEPV development), and a secondment (encapsulation development at a non-academic institution). Dr. Lorenzi will acquire knowledge and know-how especially by training through research in achieving the objectives of the action. This will contribute to make Dr. Lorenzi an independent and expert researcher in the perspective of his future research carrier. The project will also surely contribute to the advance of field of the energy harvesting. Actually it is well known that for renewables, the higher the efficiency the lower is the total-cost/produced-power ratio. Thus the large expected increase of efficiency for the hybrid devices developed in this action will have a major impact on their price per watt. This will open new concrete possibilities for near-future commercialization of this novel generation of solar harvesters, stimulating industrial productions and new markets. This in turn will lead to a wider diffusion and a higher acc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'A Novel Microsensor for Measurement of Liquid Flow and Diffusivity'.

assistant: **Objectives**

A microsensor for flow and diffusivity based on a completely new principle hasbeen invented under MAST project CT950029 Micromare". It is based on the diffusive loss of a tracer from a reservoir through a membrane-filled pore. The tip of a transducer specific for the tracer is situated near the outer side of the membrane where it detects concentration changes. As the concentration gradient through the membrane is dependent on both the diffusive properties of the tracer in the membrane and advective transport or diffusive properties of the tracer in the external medium, the reading from the microsensor represents flow or, in stagnant media, diffusivity. The new microsensor is small (down to 10 m tip diameter), inexpensive, has a low energy requirement and can quantify flows over 4 orders of magnitude plus diffusivity in stagnant media. We will optimise this new sensor by choosing the best suited tracer and by optimising the detection of this tracer by the built-in transducer. As the signal from the new sensor will be dependent on temperature, means of optical or thermocouple temperature compensation will be investigated and implemented. The new sensor with built-in temperature compensation will be used on a benthic lander in both shallow waters and in the deep sea. For deep sea use, a pressure stable (600 bar) sensor filled with liquid will be developed. The new sensor will be protected by patents and the feasibilily of commercial production and marketing will be investigated. The potential use of the new sensor in fields like medicine, physiological research, and micro-mechanics will also be investigated."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Real-Time Monitoring Networks and Transport Emissions for Tailored Zero Pollution Action Plans in European Cities'.

assistant: **Innovation**

The transport sector is a major contributor to environmental degradation, including air and noise pollution that have negative effects to ecosystems and human health. This is particularly critical in urban areas, where the confluence of transport emissions and high population density result in adverse health impacts and substantial economic burden. The upcoming changes in the transport sector will be critical to reach targets set by the EU Green Deal. The Zero Pollution Action plans are essential tools to reduce pollution at many different levels. Through co-creation with stakeholders Net4Cities will facilitate the realization of the zero-pollution vision by 2050. The backbone of Net4Cities is this transdisciplinary approach in which the consortium members will engage with the partner cities, including ports and airports, to jointly produce new knowledge, and ensure relevance, uptake, and maximize transferability and exploitation. During the project, air and noise pollution monitoring infrastructure will be advanced and expanded in 11 European cities, including transportation hubs such airports and ports, to conform with upcoming directives and provide data for health impact assessments. The activities are designed to have long-lasting impact through both mid-, and long-term pathways, providing a roadmap for greater uptake in European cities by offering tailored, transferrable, evidence-based support for implementing effective management strategies for reducing transport-related emissions. The main project results will be consolidated in the Net4Cities Studio which will provide (1) a web-based interface with real-time maps and information to raise awareness, and (2) a support tool for policy decisions that will provide guidance for operationalization and recommendations
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'COntinuous variables Quantum COmplex Networks' in the context of a Horizon 2020 call.

assistant: **Objectives**

At different scales, from molecular systems to technological infrastructures, physical systems group in structures which are neither simply regular or random, but can be represented by networks with complex shape. Proteins in metabolic structures and the World Wide Web, for example, share the same kind of statistical distribution of connections of their constituents. In addition, the individual elements of natural samples, like atoms or electrons, are quantum objects. Hence replicating complex networks in a scalable quantum platform is a formidable opportunity to learn more about the intrinsic quantumness of real world and for the efficient exploitation of quantum-complex structures in future technologies. Future trusted large-scale communications and efficient big data handling, in fact, will depend on at least one of the two aspects -quantum or complex- of scalable systems, or on an appropriate combination of the two.In COQCOoN I will tackle both the quantum and the complex structure of physical systems. I will implement large quantum complex networks via multimode quantum systems based on both temporal and frequency modes of parametric processes pumped by pulsed lasers. Quantum correlations between amplitude and phase continuous variables will be arranged in complex topologies and delocalized single and multiple photon excitations will be distributed in the network.  I aim at:-Learn from nature: I will reproduce complex topologies in the quantum network to query the quantum properties of natural processes, like energy transport and synchronization, and investigate how nature-inspired efficient strategies can be transferred in quantum technologies. -Control large quantum architectures: I will experiment network topologies that make quantum communication and informatio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Intelligent semi-autonomous vehicles in materials handling'.

assistant: **Concept**

Foreseen ResultsVirtual engineering for industrial mobile robotics/vehicles; a virtual design environment is used for pre-emptive learning / training of intelligent semi-autonomous human guided vehicles and the optimisation of operation strategies.Advanced control architectures for intelligent semi-autonomous vehicles and intelligent guided vehicles.New smart sensing techniques for industrial mobile robotics/vehicles.A fundamentally new approach in building the control and sensing infrastructures for mobile vehicles applying field-bus type control networksThe primary aim of this research is to improve the operation, safety, self protection, efficiency and flexibility of semi-autonomous guided vehicles / assembly carriers through intelligent control and smart sensing techniques in materials handling and related applications. This will lead to safer, highly effective and responsive man-in-the-loop materials handling in manufacturing environments (e.g. automotive assembly) and hazardous environments (e.g. nuclear plants, mine clearance, bomb disposal, etc.).Manufacturing industry and other industrial sectors require the extensive movement of products, tools and materials through out the production process. Materials handling is therefore an extremely important aspect of the overall manufacturing process which adds value by changing the temporal and spatial arrangement of products and materials inline with manufacturing goals. Assembly carriers and guided mobile robots are used to meet some of the materials handling needs, particularly in industries such as automotive manufacturing where the product and materials tend to be large and heavy which are difficult to manipulate by other means. Such handling systems need to be highly flexible to meet changing production schedules