RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'What Can We Learn from Late-Onset Schizophrenia? Comprehensive Genomic and Clinical Characterization of Late-Onset versus Normal- and Early-Onset Cases' (LOSZGENPHEN).

assistant: **Innovation**

Schizophrenia (SZ) is a debilitating disorder affecting 1% of the population and shows a strong genetic component. Onset of SZ is usually before age 40, but 1.2% have onset after 40. These individuals show marked differences from earlier onset, including more female cases, improved cognition, and more paranoid symptoms. The burden of late-onset SZ (LOS) is likely to grow due to the ageing population in Europe. However, little research has been conducted on LOS and the genomics of LOS have not been examined.Recent technological breakthroughs have allowed the interrogation of the genome to uncover the genetic underpinnings of SZ, and genome-wide association studies (GWAS) have been successful at finding replicated associated markers. To date, studies have not examined genetic differences between LOS and earlier onset cases. The proposed study will be the largest to examine clinical and genetic correlates of LOS vs normal onset (NOS; 18-39 yrs) and vs early onset (EOS; <18 yrs), with 400 LOS and 25,000 N/EOS.Utilising WTCCC2 GWAS data (50 LOS), the minor allele of a single nucleotide polymorphism (SNP) in the gene PREX2 was GWAS-significantly more frequent in LOS vs NOS cases and this association was replicated in an independent GWAS (79 LOS). In both GWAS, the minor allele was most frequent in LOS (10-13%), intermediate in NOS (2-4%) and lowest in EOS (1-2%), suggesting a protective effect against earlier development of SZ. In controls, the frequency of the minor allele was 4-6%, indicating it was not conferring LOS-specific risk. PREX2 is part of the RAC1 pathway containing several SZ candidate genes and GWAS support association of PREX2 with working memory and processing speed. A knockout mouse model has shown SZ-related phenotypes.Identification of genetic factors prot
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'New and old World perspectives for forest ecology and management in a context of global change'.

assistant: **Objectives**

The NEWFORESTS exchange program brings together researchers from 5 research institutions: two from public research centres in Spain, Forest Sciences Centre of Catalonia (CTFC) and Centre for Ecological Research and Forestry Applications (CREAF), one French institution, Bio-Archaeology and Ecology Centre (CBAE), and two Canadian Universities (University of Quebec in Montreal, UQAM, and in Abitibi-Témiscamingue, UQAT) hosting two of the main hubs of the Centre for Forest Research (CEF). During three years, a total of 36 senior researchers will participate in the program with a total of 328 man-months including experienced and early stage researcher, technical and management staff from the different centres. The aim of this proposal is to create a competitive platform at the international level to analyse the responses of forest ecosystems to global changes and integrate current knowledge in sound and innovative forest management and planning approaches. The general objective of the program is to determine how to effectively integrate woodland management (including non-management options) into strategies aimed to adjust and mitigate global change. The program is organized in 5 thematic work packages ranging from the basic understanding of forests dynamics, biodiversity and functioning (WP 1 and 2) to research on interactions between global change drivers determining disturbances regimes (WP 3) and the integration of the gathered knowledge into advanced modelling tools (WP 4) and sound management guidelines at different spatial scales (WP 5). Finally, a project management WP (6) depicts the practical organisation and management of the project.A fundamental aspect of the program is that it stresses not only the responsibility of human society as a major driver of global chan
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Cross-KIC Strategic Regional Innovations Cluster' under Horizon Europe.

assistant: **Concept**

As the Strategic Innovation Agenda (SIA) of the European Institute of Innovation and Technology (EIT) 2021-2027 sets out, the EIT, primarily through its Knowledge and Innovation Communities (KICs) and by expanding its Regional Innovation Scheme, should aim to strengthen innovation ecosystems that tackle global challenges.Cross-KIC Strategic Regional Innovations is a horizontal project fulfilling the above requirements by providing a platform for the KICs to share best-practices and KIC initiatives and identify joint activities within those Emerging European regions that are labelled as modest and moderate innovators, specifically EIT RIS regions and countries and the Western-Balkans. Objective: Maximise the EIT Community’s impact in the EIT Regional Innovation Scheme area as well as other priority countries and regions Work PackagesProposed activities under the Work Packages address a need emerging from the local innovation ecosystem and validated by a group of experts:1.EIT Jumpstarter and EIT Post-Jumpstarter (EIT Jumpstarter Next from 2025) – addresses the need to support entrepreneurial education and boosting entrepreneurship in our region.  2.Western-Balkans – addresses the need for a closer business-academia collaboration 3.Ukraine – addresses the needs of Upskilling/Reskilling talents into entrepreneurs and providing access to European opportunities locally to decrease brain-drain 4.Cross-KIC Hub Collaboration- addresses the need for closer collaboration of the RIS Hubs within the same country and increase the visibility of the EIT Community 5.Communication and Management – addresses the need for effective management of the project Work Packages of the project are interconnected with each other to ensure strategic alignment and de-siloing of the activities propos
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Reactive and inelastic process in the gas-phase at ultra-low temperatures' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Research objectives and content The main aim is to measure rate coefficients for both reactive and inelastic processes in the gas phase at temperature down to 10 K. All the proposed experiments would be carried out in the ultra-low temperature environment of the CR (Cinitique de riaction en Ecoulement Supersonique Uniforme) apparatus available at the University Birmingham, using pulsed lasers to create and probe radicals or specific rovibrational states. The principal objectives at ultra-low temperatures are: ? the use of CN spectroscopy/lcinetics to commission the apparatus, and determine the product state distribution the reaction CN + 02 o NCO + O ? the determination of rate coefficients of atom-molecule reactions (involving Carbon atoms) ? the measurement of state-to-state rates of collision-induced energy transfer between selected rovibrational states of simple molecules (initially NO, C2H2). Training content (objective, benefit and expected impact) Our aim is to provide an extensive kinetic data base for the models of astrophysical environments such interstellar clouds. The completion of this task will play a major part in understanding the origin and evolution the solar system, especially of planetary atmospheres. An other significant interest is to test current theories of reaction kinetics/dynamics and energy transfer. Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Genetic/epigenetic basis of ethnic differences in cancer predisposition' (ECAP) under Seventh Framework.

assistant: **Objectives**

Integration of large scale genetic and epigenetic analysis needs to be coupled with well defined biological hypotheses that can be experimentally tested. This project is aimed at developing a novel integrated approach to understand genetic and epigenetic predisposition to cancer with skin as model system.The Caucasian (West European) and Asian (East Asian) populations differ substantially in their predisposition to skin cancer, specifically Squamous Cell Carcinoma (SCC). The underlying mechanisms are poorly understood. As in other organs, skin SCC results from changes in both epithelial and mesenchymal compartments. We will be focusing on two key gene regulatory networks of cells of the two compartments (keratinocytes and dermal fibroblasts), with a key role in skin SCC. The ""keratinocyte network"" has Notch/p53/p63 as key nodes, while the ""dermal fibroblast network"" had Notch and AP1 family members. We will pursue two main goals :1) We will test the hypothesis that a linkage can be established between specific genetic and epigenetic marks in the Caucasian versus Asian populations and differences in expression and function of ""keratinocyte and/or dermal fibroblast network genes"".2) We will test the hypothesis that keratinocytes and/or dermal fibroblasts of Caucasian versus Asian individuals differ in their tumor yielding capability, and that these differences in cancer forming capability are due to differences in either ""keratinocyte or dermal fibroblast network genes"".The applicant is a world leader in epithelial signaling and cancer biology, and is heading interdisciplinary research efforts that bridge the basic and clinical sciences. Together with his bioinformatician and clinician collaborators, he is in an excellent position to attain the high goals of the p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Misfires and Market Innovation: Toward a Collaborative Turn in Organising Markets' to be submitted under Horizon 2020.

assistant: **Abstract**

MISFIRES opens up new theoretical and empirical horizons for analysing and innovating ‘concerned markets’, where multiple actors’ interests, values and concerns clash. It asks how actors can engage with a market’s failures to challenge its organisation and make it more collaborative, more open to civic values and to social or political concerns. Concerned markets are contested by diverse actors with equally diverse perspectives and value measures. Evaluating such a market’s efficiency is as much of an illusion as redesigning its inner workings on a blackboard. We need new conceptual frameworks to understand how to innovate concerned markets from the inside to make them ‘better’ (as defined by concerned actors), and we urgently need empirical insights into how collaborative action in markets with such social and political stakes may translate into market change. MISFIRES relies on science and technology studies, pragmatic sociology and critical market studies to shift thinking around market organisation from failure and design to collaboration and experimentation. I devise an ethnographic and participatory inquiry to explore how a market’s failures can lead us to markets that are more attentive to and accommodating of the concerns they create. I choose three exemplary contested markets in healthcare (licensing of antiretroviral drugs, Hepatitis C pricing, and the sale of DNA information) and two emergent controversies to investigate the activities concerned actors undertake, and the instruments and devices they experiment with, to re-organise that market. MISFIRES will comprehensively map, engage in, and conceptualise this collaborative turn in organising markets. With this, MISFIRES will guide new academic and policy thinking by establishing how: 1) concerned actors voi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Imaging the Plasmonic Activity of Magnetic Nanostructures' to be submitted under Seventh Framework.

assistant: **Abstract**

The proposed project concerns the study of magnetoplasmonic systems, that is nanostructures exhibiting both magneto-optic (MO)  properties and surface plasmon resonances (SPRs). Particularly, localized SPRs appearing in magnetic nanostructures will be studied using local probe microscopy techniques.The typical magnetoplasmonic nanostructure is a Noble-Metal/Ferromagnetic-Metal/Noble-Metal trilayer. They can be fabricated either as continuous thin films that are subsequently patterned using lithography and etching, or by lithography, evaporation and lift-off. Nanostructure arrays will be fabricated in various compositions, shapes, separations and symmetries (in particular, colloidal lithography will be used to obtain disordered arrays, whereas e-beam lithography will be used to prepare ordered ones). First, their collective optical and MO behavior will be characterized using far-field measurements. Afterwards, the local electromagnetic near-field distribution at single objects will be imaged using Scanning Near-field Optical Microscopy (SNOM). The local measurements will be correlated to the optical and MO collective measurements. Both optical-fiber SNOM and apertureles SNOM (aSNOM) measurements will be performed. Metal-coated Atomic Force Microscopy (AFM) tips will be used for aSNOM. The interest is in performing aSNOM using ferromagnetic-metal-coated AFM tips, thus allowing for Magnetic Force Microscopy (MFM) measurements to be performed simultaneously with SNOM. The illuminated light will excite surface plasmons, and the magnetic component of their electromagnetic field distribution will be imaged using MFM.Magnetoplasmonics research has been pioneered at the host group, and the proposed project is a natural continuation of the so far host activity. Magnetoplasmonics
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Collaborative Actions to Bring Novel Biofuels Thermochemical Routes into Industrial Scale'.

assistant: **Objectives**

BioTheRoS Project aims at developing a holistic methodology that will boost the scale-up of sustainable biofuels via thermochemical conversion technologies. These are pyrolysis upgrading through hydrodeoxygenation and Fischer-Tropsch synthesis from biomass gasification. The project will bring together key actors at a both European and International level, such as technological and social experts, renewable energy-oriented associations along with industrial experts that will bring and exchange their knowledge in order to reach the project targets. Within the project, several non-food biomass feedstock will be analyzed and optimized across their entire value chain. Barriers linked with the selected feedstocks supply and pretreatment will be identified. Furthermore, AI-based predictive models will be developed, in order to be adapted to the scale-up cases. Then, the most promising biomass feedstock will be tested experimentally in the studied thermochemical reactors. At this point of the project, technical constraints and opportunities for the scale-up of the sustainable biofuels thermochemical processes will be identified. Possible synergies of blending pyrolysis oil and gasification based advanced biofuels will be investigated by a potential end-user (petroleum company). The selected data will be used as an input for advanced modelling tools, including process modelling, CFD tools and LCA/LCC/sLCA tools results of which will feed a multi-criteria analysis to derive generalized up-scaling rules and guidelines of the produced biofuels. The engagement of several stakeholders in the planning of the scaling-up of sustainable biofuels production will be crucial at this point, since they will review the project results and assess if a biofuel production technology can be delive
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'No Researchers ? No Party !'.

assistant: **Concept**

No Researchers ? No Party ! expresses in its title the concept of the proposal: offer, on the 25th of September, to the public at large a unique event to better know researchers and their role, to interact and to party with them. The Re-party project is conceived as a catalyst of resources, ideas, energies and expertise as it’s structured on 3 key pillars: continuity, creativity, communicability (3C). These three key words characterize the findings of the 2008 impact assessment activities and summarize perfectly the areas where partners will focus their efforts. The consortium, with the support of a large number of local and regional stakeholders, will set up a festive programme to be performed in the 7 venues of the 2 involved regions: Piemonte and Aosta valley. The Re-Party project is thus impacting on the North West of Italy. More than 200 researchers have been mobilized in the 2 regions to brainstorm and to propose activities for the Night: Re-Party project will organize a mix of multidisciplinary experiments, games, entertainments, debates with music, sounds and light. Citizen will find activities in the streets and in open venues as well as and in labs, theatres, cafés, museums. Novelties for the 2009 Night are: a reinforced participation of SMEs, the contribution of Ispra JRC for the EU corner, a massive use of the social network’s tools to reach the identified target audience (younger generations and students), the willing to assess the national impact and to open to EU partner regions and generally to go beyond the regional boundaries. Re-Party wants to plan an evening where all the involved parties, namely public and researchers, get together and discover each other under a different light!
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Novel microwave-assisted vacuum drying for heat sensitive foods' (MILD-DRY) targeting Seventh Framework.

assistant: **Abstract**

Heat sensitive foods and products that possess excellent quality in terms of taste, aroma, texture, and appearance, such as herbs, spices, seafood, etc., pose a major challenge to food driers. Products such as garlic, ginger, spring onions and shrimps are cellular tissues containing gas-filled pores that tend to collapse when subjected to dehydration. This collapse is more noticeable with prolonged exposure to elevated drying temperatures, such as those used in convective drying. For this reason, hot air drying results in substantial degradation in quality attributes such as colour, nutrients and flavour, sever shrinkage also reduces bulk density and dehydration capacity. Also, chemical changes causing loss of flavour and nutrients occur during convective drying so the properties of dehydrated products are poor. A number of drying techniques have been developed over the years, among them atmospheric forced-air dehydration, a very common method. The major disadvantage of the hot air convective drying of food is the low energy efficiency and lengthy drying time during the falling rate period.MILD-DRY will build on the positive results of laboratory trails using microwave-assisted vacuum drying (MAVD) for the successful dehydration of selected foods, whereby the drying time for carrots for example was reduced to 2 h compared with 4.5-8.5 h in convectional hot air drying. Moreover, dried carrots showed higher rehydration potential, higher beta-carotene and vitamin C contents, lower density, and softer texture than those prepared by air drying. Further research effort will be performed in order to optimise the approach through the intermittent as opposed to continuous application of MW in order to achieve higher energy savings and product quality enhancement. To bridge the g