RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Atomic Scale Group-IV Materials for Beyond-CMOS Applications' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

I will systematically exploit the quantum properties in Group-IV Materials (GFMs) at the atomic scale, by using top-down patterning processes developed for Si technologies. Among GFMs, I will examine graphene, Si, and Ge nano-structures, since these materials are technologically important. More specifically, I will use our He-Ion-Microscope (HIM) milling techniques to fabricate nano-structures beyond the resolution limit of conventional lithography. This research will:1. Characterize Freestanding Mono-layer or thin-layer of GFMsI will fabricate the freestanding device structure by HIM. The high-resolution of HIM will enable me to fabricate the graphene nano-ribbon as narrow as 5-nm. I will also examine the atomic structures of the device by Transmission-Electron-Microscope (TEM), and compare it with electrical measurements. The similar devices can be made for ultra-thin Si films.2. In-situ formation and characterization of Si Quantum Dot (QD)I will characterize the Si Single-Electron-Transistor with a QD by in-situ monitoring in HIM.3. Characterization of SiGe FinsI will characterize SiGe Fin for high performance electro-absorption optical modulator applications.Impacts of the projects to EU are expected as following ways:1. I will contribute in the interdisciplinary research areas with my strong research background in theoretical physics, nano-electronics, and Si Photonics.2. The long-term research activities to QIP will be continued for secure communication and massive commutation, beyond the limit of the classical computations.3. I will transfer my research experience from Japan. Especially, the industrial experience in Hitachi is helpful for running the clean room managements.4. I will explore the innovative opportunities for sustainable electronics, in which EU com
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Roof solutions for natural cooling' to be submitted under Fourth Framework.

assistant: **Abstract**

Objectives The two main R&D objectives of this project are:  The creation of Design information in which energy performance indices will accompany a classification of roof solutions and components feasible for the Mediterranean area.  To provide valuable examples at real scale of roof components together with a thorough analysis on performance and on its potentialities for saving energy in a diversity of localities (climates) across the Mediterranean area. Technical Approach A selection of five roof components (selected among the most feasible natural cooling techniques for the Mediterranean region) will be built, thoroughly analysed and tested. The efforts will be concentrated on components based in the two most feasible techniques for natural cooling by roof solutions: i) cooling by roof-top evaporation, (like water sprays over pebbles roofs , roof water ponds or roof vegetation techniques ) ii) radiative cooling. (like selective wavelength radiator with or without movable day-time insulation, flowing liquid and in combination with different cool storage systems). To build the information package four tasks are foreseen:  Elaboration of a roof design handbook and directory: The Handbook will cover design principles, built examples, testing results and performance indices. A Directory of roof solutions and components will be annexed as result of consultancies, surveys and interviews.  Development of Models: to analyse and optimise each of the five types of components and to allow the development of reduced/simplified models able to be integrated in existing building analysis tools.  Testing: Two types of test facilities will be used for this purpose: the PASSYS type test cells with removable roof and full scale demonstration buildings. These facilities allow the testin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Safe, Transparent, Active and Reliable mineral sunscreen technology' to be submitted under Horizon 2020.

assistant: **Abstract**

Our product, MicNo®, is a patented Zinc Oxide UV filter for use in cosmetic formulations. MicNo® are designed platelet-shaped micron particles composed of nano primary particles - developed to exploit benefits of the nano-size particles while removing adverse effects of them.The aim of this project is to mature, in-vivo test and commercialise MicNo® onto the global markets. We had been awarded Phase I funding and we have conducted a Feasibility Study (GAN #741192) that verified the market potential. Our product is at TRL 7 and this project will enable us to bring our solution to TRL9 ready for commercialisation on the global cosmetics market valued at $454 billion with CAGR of 6%.MicNo® has gone through in-vitro testing, toxicity tests as well as efficacy tests – they all showed superior broad-spectrum protection with up to 60% improvement vs. main competitors, improved transparency at application by 15-20%, mitigation of safety and health concerns related to nano zinc particles. As well as high area coverage/unit mass – a 40% reduction in raw materials usage for same UV protection.Europe is the global flagship producer of cosmetics with a market valued at €77 billion and exports exceeding €33 billion. Thousands of companies are involved in manufacturing of cosmetics in Europe – utilising our UV filter in cosmetic formulations improves cosmetic and health benefits vs. current ZnO ingredients. We offer a solution for safer sun care products without endocrine-disrupting chemical UV filters and with lower production costs. Considering 150-200 million bottles of sunscreen are sold annually in EU this would translate to savings of €75 to €100 million/year. Moreover, we believe that our unique technology will encourage large sways of population to utilise more sun care produc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'NON INVASIVE DIAGNOSTIC TEST SERVICE FOR “NON ALCOHOLIC FATTY LIVER DISEASE” MANAGEMENT' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The overall objective of the project as a whole is to provide to the global clinical community a non-invasive diagnostic tool for the management of the NAFLD (Non Alcoholic Fatty Liver Disease) through an ON-LINE SERVICE OF DIAGNOSTIC TEST as alternative to Liver Biopsy.This project innovative approach is based on two verified proprietary imaging biomarkers linked to the evidence of NASH existence (Non Alcoholic Steatohepatitis) and fibrosis staging in patients with NAFLD, as well as a robust analytical method based on the optical analysis of a liver MRI (Magnetic Resonance Imaging) for the evaluation of these biomarkers.Currently, no validated non-invasive tests are available to differentiate simple steatosis from NASH. Unmet need for NAFLD management is the development of non-invasive methods able to detect NASH and predict advanced fibrosis in a cost-effective, immediate, widely available, and accurate way.This project faces a global unmet need and proposes a solution with ambitions of global scope based on a business and operational model that can afford this approach from an European perspective.With this proposal, Radiologists, Gastroenterologists, Hepatic doctors as well as primary care Doctors, will have access to an early screening of patients with NASH and therefore to an early and cost-saver approach to its treatment strategy, through an accurate on-line service of diagnostic tests based on a business model that anticipate a higher cost-effectiveness ratio compare to liver biopsy.Our feasibility assessment under Phase I work expect to validate that the business idea is achievable by the analysis of the technical and economic related aspects with the proposal and, at the same time, identifying those key issues to face in Phase II, jointly to the clinic validat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Essential Asymmetries of Nature' (ASYMMETRY) targeting Horizon Europe.

assistant: **Abstract**

The symmetries identified in Nature, explicit or hidden, are at the root of our knowledge in depth of its fundamental laws. Nevertheless, observed asymmetries –departures from that exact pattern-- are at the very heart of its beauty and of the explanation of how   the visible Universe came to be, and what we are made of. Well known examples include the matter-antimatter asymmetry of the Universe and the violation of parity and charge conjugation observed in particle physics. ASYMMETRY focuses on the deep understanding of those asymmetries and also on revealing the new fundamental (a)symmetries yet to be discovered to explain major open questions, and the particles on which they act, in particular in the invisible sector, made of neutrinos, dark matter, possibly axions  and other elusive particles. The team is strongly focused on this quest within a multidisciplinary approach: mainly phenomenological studies although we bundle in leadership on key experiments such as SuperKamiokande, GERDA, XENON and key laboratories such as Fermilab, DESY and LBNL.


**Keywords:** Neutrinos, CP- Violation, Matter- Antimatter asymmetry of the Universe, Asymmetric Dark Matter,  Axions and ALPs, Flavour puzzle, Astroparticle Physics, Hidden Asymmetries
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'CHEMICAL-FREE TO REHABILATE WATER WELLS AND PREVENT IRON RELATED BACTERIA CONTAMINATION' (PEM).

assistant: **Innovation**

Pollution of water wells caused by iron bacteria can block filters, which leads to the quantity of water decreasing until it stops the pump. The different methods used to solve this problem are expensive and they do not return the system to the initial pumping efficiency. Operators often allow pollution to develop and only carry out remedial action when the pump-station is not able to meet users demand. Therefore economically and environmentally it is important that preventive maintenance of water wells be developed.This project planned to introduce the EMP process (Electric-Magnetic-Pasteurizing) as a preventive treatment process for well pollution caused by iron-bacteria. The EMP-Process consists of heating in a selective way the well filter and its immediate proximity by the use of an induction process. A temperature of 70 C (kept for a few seconds), is able to kill the iron-bacteria which are present on the well filter. Among all the processes used to fight iron-bacteria, heat is certainly the most efficient and the most environmentally friendly.A market study showed that water well operators are interested in seeing this process developed further, so long as there is a reduction in the exploitation costs. The low cost of applying this process (in comparison with the cost of chlorination) shows that the market is limited by the supply and not by the demand. The market for this equipment for underground water sources in Europe is potentially several hundred units per a year. The market potential for export (USA, CANADA) is also promising.The project was successful as it appeared to have solved a significant problem for the EU mineral water industry, as well as having a wider application in other countries including the third world. The team involved a multi -discipli
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Enhancement of motor learning by transcranial direct current stimulation (tDCS) after chronic stroke' (2002-2006), addressing dissemination and exploitation.

assistant: **Impact**

Chronic motor disability, present in two thirds of stroke survivors pose tremendous personal and social burden. There is no universally accepted treatment for motor disability resulting from stroke. Recent studies demonstrated that rehabilitative training can improve motor function and relearning after stroke. However, these approaches lead only to partial amelioration.It is crucial to develop novel strategies to enhance functional recovery after stroke. It has been proposed that cortical stimulation can enhance brain plasticity. New understanding of mechanisms of plasticity led to the preliminary finding that transcranial direct current stimulation (tDCS), a form of non-invasive cortical stimulation, can safely enhance motor performance of the paretic hand in patients with chronic subcortical stroke.These findings suggest that tDCS, in association with motor training and through Hebbian principles, could enhance recovery processes. The two main hypotheses of this proposal are- that tDCS can improve performance/learning of a finger motor sequence by the paretic hand after both subcortical and cortical stroke relative to sham; and- that the mechanisms and neural substrates underlying this effect will include reorganisation within ipsilesional primary motor and premotor cortices.During the outgoing phase, anodal tDCS and sham will be applied in chronic stroke patients over the motor cortex, in synchrony with motor training consisting of performance of finger motor sequences in a double blind, sham control led experimental design.Endpoint measures of the study will be- performance of newly learned motor sequences,- reorganisational changes in motor and premotor cortices identified by functional magnetic resonance imaging and transcranial magnetic stimulation associated wit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Milk proteins as carrier proteins in the delivery of bioactive peptides with blood pressure lowering and satiety inducing effects' under Sixth Framework.

assistant: **Concept**

Orally administered bioactive peptides are largely degraded during gastrointestinal digestion. This study examines the possibilities to use milk proteins to deliver bioactive peptides in an active form to target tissues through the intestinal mucosa and thus enhance biological activities of these important compounds. This would have a great impact on preventing the major health risks in the population, such as hypertension, obesity and the metabolic syndrome. Bioactive peptides examined in this project will be chosen based on their favourable biological effects and characteristics that allow them to bind to the carrier proteins.The carrier proteins used in this study are milk proteins, primarily beta-lactoglobulin and natural and mutated caseins. The complexes formed will be characterized by molecular modelling, ultra-filtration and isothermal titration calorimetry (ITC) and their resistance against gastrointestinal degradation will be assessed. Promising protein-peptide complexes will be chosen for further structural studies.Finally, the passage of the carrier proteins complexed with the bioactive peptides through enterocytes and M-cell monolayers will be examined, and preservation of biological activity analysed.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Accelerated Atherosclerosis in Patients with Immune Mediated Disorders as a Model to Investigate the Link between Inflammation and Cardiovascular Disease: From Basic Mechanisms to Clinical Application' (2007-2013).

assistant: **Concept**

Atherosclerosis is a chronic inflammatory disease of the arterial wall with (auto)immune component, initiated in response to modified (phospho)lipids. Despite important advances in our understanding of the inflammatory response in atherosclerosis, the critical pathways responsible for the breakdown of immune tolerance to lipoproteins and other self-antigens remain largely unknown. An important feature of ruptured/thrombosed atherosclerotic lesions is the accumulation of apoptotic, and secondary necrotic, lipid-laden macrophages and smooth muscle cells due to defective efferocytosis (clearance of apoptotic cells). This leads to the formation of a large ‘necrotic’ lipid core, associated with enhanced vascular inflammation. Interestingly, defective efferocytosis has been associated with the development of autoimmunity, and patients with systemic lupus erythematosus who show increased accumulation of apoptotic material are at very high risk of accelerated atherosclerosis and myocardial infarction. We hypothesize that accumulation of apoptotic/secondary necrotic cells due to defective efferocytosis, together with modified lipids, activate critical immuno-inflammatory pathways in macrophages and B cells, and break immune tolerance in atherosclerosis and post-myocardial infarction. This is consistent with the critical role played by defective efferocytosis and macrophage activation in atherosclerotic lesion progression, and with our recent unsuspected data showing a critical role for B cell activation in driving lesion development in several models of atherosclerosis. We also propose that interactions between macrophages and B cells are essential for the perpetuation of the pathogenic immuno-inflammatory response in cardiovascular disease. Finally, we will harness this knowled
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'A Quantum Switch for Light'.

assistant: **Objectives**

Optical switches are devices that allow rerouting an incident optical signal to different ports and play a vital part in fiber optic communication networks. The realization of future quantum networks and quantum communication applications require so-called quantum switches, which, in contrast to classical optical switches, have to be treated quantum mechanically. In particular, quantum switches can be prepared and operated in coherent superposition states.We propose the experimental implementation of a fiber based quantum switch, for which the internal state of a single laser-cooled atom defines the output port of the incident light field. The key element of this proposal is a novel type of optical whispering-gallery-mode microresonator. It allows one to reach the regime of strong coupling, where a single atom is sufficient to drastically change the transmission properties of the resonator. The coupling of light into and out of this so-called bottle microresonator is realized with very low losses using tapered optical fibers. This fiber integration in conjunction with the extremely high optical quality of the resonator enables the realization of a highly efficient quantum switch with properties adequate for real applications.In addition to its potential use in quantum communication, an intrinsic property of this quantum switch is that it allows one to efficiently generate matter-light entanglement as well as highly entangled multi-photon states as, e.g., Schrödinger cat states. This is interesting both from an applied and from a fundamental point of view because the number of entangled particles can easily be adjusted, thus allowing the quantitative study of the transition from the quantum mechanical behaviour of the switch to the classical regime.