RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Innate Immune Cell Swarms: Integrating and Adapting Single Cell and Population Dynamics in Inflamed and Infected Tissues' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

Neutrophils are essential effector cells of the innate immune response. Intravital microscopy studies have recently changed our perspective on neutrophil tissue dynamics. They revealed swarm-like migration patterns in several models of inflammation and infection: Neutrophil populations show strikingly coordinated behavior with phases of highly directed chemotaxis and clustering at local sites of tissue damage. My previous work established that neutrophils self-amplify this swarming response by auto-signaling, which provided the first molecular basis for the collective nature of neutrophil swarms (Lämmermann et al., Nature 2013). However, we are still at the beginning of unraveling the molecular pathways behind this newly discovered phenomenon. Most importantly, we completely lack insight into the signals and mechanisms that stop neutrophil swarms in the resolution phase of an immune response. Since excess neutrophil accumulations cause deleterious tissue destruction in many inflammatory diseases, novel insights into the mechanisms, which prevent extensive swarm aggregation, might be of considerable therapeutic value. In accord with this, our proposal follows three aims: (i) dissecting the cellular and molecular mechanisms that control the resolution phase of neutrophil swarming, (ii) establishing a conceptual framework of how swarming immune cells adapt their dynamics to changing inflammatory milieus, and (iii) developing an integrated view on how neutrophil swarms are controlled by secondary waves of myeloid cell swarms. To achieve our goals, we will combine targeted mouse genetics with live cell imaging of immune cell dynamics in living tissues and the use of innovative mimics of physiological environments.Our future findings on innate immune cell swarms promise to (i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Integrative Computational Materials Engineering Expert Group' (ICMEG) targeting Seventh Framework.

assistant: **Abstract**

Scope of this proposal is to establish a network of stakeholders - an ""Integrative Computational Materials Engineering expert group (""ICMEg"") -  aiming at the creation of an open, global standard for information exchange between a heterogeneous variety of commercial and academic simulation tools.The vision of the ICMEg proposal isa new strategy of materials and process development, where a variety of academic and commercial simulation tools – present and future – can be easily combined across different process steps and bridging several length scales in a “plug&play” type architecture being based on an object oriented, standardized information exchange. Multi-scale in this context covers electronic, atomistic,mesoscopic and continuum modelsThe Mission of ICMEg is• to establish and to maintain a network of contacts to (1) simulation software providers around the world (2) governmental and international standardization authorities (3) ICME type users of simulation software (4) different associations in the area of materials and processing (5) academic developers of simulation software• to define an ICME language in form of an open and standardized communication protocol• to stimulate knowledge sharing in the field of multiscale materials design• to communicate this standard worldwide to make it widely accepted• to discuss and to decide about future amendments to the initial standard• to establish a legal body for a sustainable further developmentThe Approach of  ICMEg to realize both its vision and its mission is to create a global network of all stakeholders in the area of ICME software and users by• identifying all actors in the field of ICME related simulations• creating an inventory of these stakeholders• networking of all identified stakeholders in two intern
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Research Infrastructure for Circular Forest Bioeconomy' (ERIFORE).

assistant: **Innovation**

The ERIFORE will realize the European potential to consolidate its place as a world leader in biomass based research and innovations. ERIFORE builds on a new firm alliance aiming to establish open access distributed forest bioeconomy research infrastructure across Europe enabling scientific discoveries to be transferred to new business models, novel products and services enabling sustainable growth. The research infrastructure will focus on topics supporting Circular Forest Bioeconomy concepts starting from fundamental teaching and knowledge sharing to high level research laboratories and large scale piloting facilities.This two-year action will be carried out by 11 European research organisations, 2 universities and a SME. The main objective of ERIFORE is to facilitate development the Circular Forest Bioeconomy field towards the following overall targets:1) Coordinate, complement and update major European research infrastructure to enable the full potential of available forest biomass in balance with diverse use of forests. 2) A new level of co-operation between the major RTD providers.3) Establish a globally competitive European research infrastructure.The main deliverables of ERIFORE are the following:1) To enhance the awareness, utilisation and open access of the complementary research facilities between the major European RTD providers in circular forest biorefinery.2) To prepare a conceptual design and plan for cooperation arrangements between the main European RTD providers in this field. 3) To prepare Stakeholder analysis for the development needs in the infrastructure network at European level.4) To upgrade bioeconomy competence base by providing contact interface for facilities for education and training. A plan for implementing is prepared.The suggested futur
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Regulation of plant growth by MADS box organ identity genes', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The development of organs in the plant body occurs post-embryonically and can be characterised by three distinct steps. Firstly, the position of future organ primordia must be specified. Subsequently the identity of organs is determined, followed by differentiation and growth of specialised cell types. Although substantial amount of data generated in the past resulted in identification of players involved in each step, the crucial question how organ identity determination is linked to organ growth and differentiation remains to be addressed. Several preliminary observations imply that genes essential for the specification of floral organ identity, namely MADS box transcription factors, might also play important roles in later steps of organ development and growth. Pilot experiments revealed that MADS box transcription factors are expressed during later steps of organ development and are able to interact with proteins involved in the regulation of organ growth, like TCP transcription factors. The main objective of my research will be to characterise the exact function of MADS box organ identity genes in the molecular and cellular processes underlying growth and establishment of final organ size. I intend to focus predominantly on the development of the floral organs sepals and petals in the model species Arabidopsis given their simple structure yet distinct size and identity. I will confirm and identify “late” interaction partners and targets of the MADS box proteins. Furthermore, the role of the identified genes and proteins in the growth process of floral organs will be analysed by achieving time and site specific activation/inactivation. The proposed research will not only substantially contribute to the knowledge about regulation of plant growth, but will also open n
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Mapping the Reception and Legacy of the Vikings in Europe' (NorseMap) targeting Horizon Europe.

assistant: **Abstract**

The modern understanding of the Vikings has developed over a thousand years to reflect the politics, identities and cultural memories of very different communities across Europe. This shared history impacts on many aspects of contemporary society and is appropriated in increasingly diverse ways. NorseMap posits that the oversignification of the Viking past can be approached as an ecology of interactions within which ideas of European culture and identity are made and remade. While this working hypothesis is based on observation of the current reception landscape, it is difficult to test because of a lack of data on public perceptions of the Vikings and the limitations of reception studies as currently conceived to map such a complex legacy. The guiding question that NorseMap asks – how is the Viking past used today, and how has public understanding of the Vikings evolved over time? – thus poses profound challenges for the discipline at both an applied and conceptual level. The applied challenge is how we capture widely dispersed data on uses of the Viking past in the present day. The conceptual challenge involves rethinking reception studies so it can address historical legacy at a macro level and account for the complexities of the reception ecosystem. NorseMap will make a step change in cultural heritage crowdsourcing, taking the model of app-based GIS mapping used for large-scale citizen science documentation projects and adapting it to the humanities. Reorienting the discipline to map the Viking legacy will entail drawing together various strands of reception history – Literature & Art; Branding & Tourism; Politics & Identity – and demonstrating how they have interacted to create a uniquely pliable cultural memory, using a conceptual lens inspired by Actor-Network T
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'A logistic bi-directional asynchronous tag-system for retail operations' to be submitted under Fourth Framework.

assistant: **Abstract**

The aim of ALBATROS is the development of a new identification system for goods and products that can be used in the areas where product identification is needed and using just one tag independently of the type of identification required.The objective of the unique tag to be developed under this project is to provide higher reliability in the logistic operations, enable automatic check out in our stores and make the EAS system more efficient. The tag will use RF/ID technology. The areas covered will be ASIC, Tag, R/W equipment and the Information System. The project results will be shown in a pilot installation which will be set up in a selected department of ECI's Department Stores.The results will be applied in different steps, starting from products of higher value in the garment area to reach the ultimate goal of the project that is to identify all products in the supermarket.Retail Business is involves three different type of operations, all of them strongly based on product identification systems:Logistic operations (control of the different states that items can pass through)Sales operations (computer aided check-out, goods returns, money refund,...)Security operations (basically Electronic Article Surveillance, EAS systems)Nowadays, the most popular method for goods identification is the bar-code system. This method requires the alignment of individual goods in front of an optical reader. It is prone to errors due to label abrasion or misalignment with the reader and does not provide a solution for the three operational problems above mentioned. New technology is required to implement a cost-effective identification system for goods and products that can offer functionalities which satisfy three operation areas of the retail business; allowing:Identification wit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Smart Choices für innovative regional ecosystems. The Power of Connectivity, Entrepreneurship and Science & Research.' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The 9th Week of Innovative Regions in Europe (WIRE) 2018 conference will be organised by Standortagentur Tirol in Innsbruck, Austria from 4th to 6th July 2018. The WIRE IX conference will provide a platform for stakeholders to have an in-depth discussion on the opportunities presented for research and innovation. A particular focus will lie on excellence driven programmes and extraordinary examples of interregional and cross-border open innovation practices throughout the EU (eg Smart City Project SINFONIA with Innsbruck (AT) and Bolzano (IT)). In order to increase awareness about the importance of regional innovation ecosystems, the need for action to develop further, the WIRE IX conference will be titled:The Power of Connectivity, Entrepreneurship and Basic Research.Smart Choices for innovative regional ecosystemsWIRE 2018 will provide an opportunity for regional authorities, funding agencies, political and social institutions, regional networks, companies and EC DGs to participate and to ensure synergies with multi-level policies, exchange experiences and build new networks.WIRE 2018 will cover two cross-cutting themes woven into all parts of the programme: Digitisation (impacts on research and innovation, economy, society…) and Alpine Challenges (transcending into a larger European context: urbanisation vs. remoteness, innovation in rural areas, smart villages…)Three thematic tracks towards successful innovation ecosystems have been chosen to focus discussion and participation: 1) Basic Research, 2) Entrepreneurship, 3) Connectivity.The conference programme of WIRE IX is composed of the following building blocks 1) Plenary Sessions with Keynote Speakers, 2) Parallel Sessions, 3) “Hosted by” Sessions, 4) Face-to-Face Meetings, 5) Exhibition Area, 6) Professional Site
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Dealing with Change: Women's Politics and Postwar Reconstruction in Romania Placed in Transnational Perspective, 1944–1948' (RECKON) targeting Horizon Europe.

assistant: **Abstract**

RECKON will analyze how women politicians and grassroots activists shaped the postwar remaking of the key political fields of public health, labor, foreign affairs and culture in post-World War II Central and Eastern Europe, with a focus on Romania between 1944 and 1948. In Romania and across Central and Eastern Europe, the period between the end of World War II and the start of the Cold War was one of extraordinary experimentation in women’s politics, with significant effects on postwar reconstruction. The four years between Romania’s 1944 armistice with the Allies and the 1948 establishment of the Popular Republic of Romania saw a first cohort of communist and left-leaning women politicians in office in the country (including, in 1946–1947, 17 MPs and two ministers). It saw tens of thousands of women mobilized for social work and political agitation. Most research on reconstruction stresses postwar state expansion in Western Europe and emphasizes postwar disarray in Eastern Europe. Women’s historians have focused on women in Eastern European politics in the less ideologically eclectic post-1948 period. RECKON aims to show that the postwar process of state reinvention in Eastern Europe resembled developments in Western Europe yet was region-specific through the importance women had as reconstruction planners and envisioned reconstruction beneficiaries, in a context marked by upheaval and flare-ups of violence. Merging approaches from gender history and transnational history, RECKON will advance understanding of the role of women and gender in the forging of new social contracts in Europe. It will enable the recruited researcher to enhance her expertise and professional capacities through career development and mentorship programs accessible through her host institution
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'VITNK - deciphering vitamin A and D regulation of human NK cells for cellular immunotherapy'.

assistant: **Objectives**

Natural killer (NK) cells are cytotoxic innate immune cells that defend against viral infections and cancer. As cancer is one of the leading causes of death worldwide, more effective treatment options are urgently needed. Harnessing NK cell cytotoxicity for cancer treatment shows promise, but there is still room for improvement, particularly against solid tumours, which are difficult to treat due to challenges such as limited tumour infiltration. Therefore, identifying targetable factors that enhance not only NK cell development, function, expansion and persistence, but also homing and migration are crucial to optimize cancer immunotherapies. Vitamin metabolites retinoic acid (RA) and calcitriol (CA) activate nuclear receptors (RAR, RXR, VDR) and regulate differentiation, function and homing properties of T cells and ILCs. In the VITNK project, I will systematically investigate how RA and CA as well as their nuclear receptors impact human NK cell development, differentiation, function, expansion, survival, and migration. To achieve this, haematopoietic stem cell-based NK cell differentiation cultures and short-term peripheral blood mature NK cell cultures will be used. In-depth analysis of the changes induced by vitamin metabolite supplementation and CRISPR-mediated nuclear receptor knockout using advanced cell-based assays in combination with cutting-edge single cell RNA, ATAC- and ChIP-sequencing will give a comprehensive insight into the molecular mechanisms that are governed by vitamin A and D in human NK cells. VITNK will thus establish how vitamin A and D modulate NK cell homing and migration, which is essential for efficient tumour infiltration. The purpose of VITNK is to take initial preclinical steps towards therapeutic targeting by thoroughly evaluating the po
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Insect social parasites: behavioural genomics models for understanding the basis of phenotypic evolution' (SocParPhenoEvol).

assistant: **Concept**

Understanding how diversity of life arises at the level of the genes is one of the biggest challenges in modern biology. Genomic methodologies now allow us to dissect the molecular basis of this phenotypic diversity and plasticity. However, we lack an integrated study of key phenotypic traits and their dynamic changes in an ecologically relevant setting, with the associated dynamic nature of the underpinning genes. I propose to use an inter-disciplinary approach, by uniting classical ethology with new molecular tools of genomics, to understand how genes give rise to phenotypic traits and their dynamic plasticity using an insect social parasite system as model. Insect social parasites show striking phenotypic diversity compared to their hosts and have been identified as unique models for understanding the molecular basis of phenotypic diversity and plasticity. Yet, they have remained largely unexploited so far, due to the difficulty of conducting genomic studies on non-model organisms. This project will combine for the first time the transcriptomic (i.e. multiple species comparisons of brain genome-wide RNA-seq analyses followed by candidate gene approach RT-PCR) and behavioural phenotyping in order to reveal the molecular basis of phenotypic diversity in a Polistes paper wasp social parasite system, which comprises the social parasite, the host and a related non host species. This will be a landmark project in the exploding field of Behavioural Genomics as it will ensure high replication in an ecologically relevant setting in wild populations and it will exploit a deep ethological knowledge of the model system to ensure precise integration of behaviour with new methods for dissecting molecular processes. This project offers a unique opportunity to capitalize on molecula