RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Stem cell maintenance and reactivation in lateral root initiation'.

assistant: **Concept**

Lateral roots are essential to form a dense root network allowing plants to take up water and minerals effectively from the soil. Laterals are initiated from a specific organogenic cell layer within the differentiated root known as the pericycle.The establishment and maintenance of the pericycle and the subsequent process of lateral root formation is an interesting model to study how stem-cells can be maintained within an otherwise differentiated and endoreduplicated tissue, and how these cells are re-activated into division in response to mitogenic signals.Recently the host laboratory has investigated in detail the expression patterns of D-type cyclin (CYCD) genes in roots. Whilst several CYCD genes are expressed during the establishment and proliferation of the new pericycle cells within the primary root meristem, only two are expressed in association with the mature pericycle or during early lateral root initiation.In particular, CYCD2;1 persists in the mature pericycle, but disappears on lateral root initiation, whereas CYCD1;1 is associated with proliferating primordial cells of lateral roots. In this project, I will investigate the hypothesis that the D-type cyclins CYCD2;1 and CYCD1;1 and their interactions with inhibitor proteins KRPs are important for maintaining the organogenic capacity of the pericycle and in the subsequent induction of lateral root induction.The proposed model is that CYCD2;1 maintains pericycle cells in a ready-to-go state until lateral root induction is triggered by auxin. Understanding the activity and control of these proteins is therefore of central importance to integrating an understanding of cell-cycle control with plant development.The host lab has the materials and the expertise in cell and developmental biology to carry out the pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Bioeconomy Awareness and Discourse Project' (BioCannDo), addressing dissemination and exploitation.

assistant: **Impact**

The Bioeconomy Awareness and Discourse Project (BioCannDo) will raise awareness and acceptance of the broad public towards the bioeconomy and bio-based products through a strategic, stakeholder-driven information campaign and education. Convincing people that the bio-based economy offers something desirable, with new products, functionalities and applications for their daily life, that provide answers to societal concerns (e.g. climate change), requires neutral and science-based information. BioCannDo will present such information in a way that is easy to understand for the broader public.  It will provide various means for feedback, interaction and encourges engagement in a discourse on common questions and concerns.  Collaborating with bio-based stakeholder networks and communities at EU, regional and national level, BioCannDo will provide information, educational materials and key communication messages through such channels as a community of related projects and educational partners and an Inhub which combines different means of online communication (i.e. social media, blogs, videos, journalistic articles). BioCannDo  will build on the legacy of previous projects (i.e. by using their networks, or social media accounts), existing material developed by them and be active in collecting, connecting, aggregating and reformulating content from different actors and resources. It will generate new content addressing the most urgent gaps in information and education. Such dual approach will help to maximise synergies and increase impact of both existing and new material. The developed content and key communication messages will be assessed and tested by stakeholders and target users through focus groups and a market survey. Findings will be used in feedback loops to adapt th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Design of ice-axes and crampons' (1994-1998).

assistant: **Concept**

Scientific research into the effect of design parameters on dynamic stresses, strains and fatigue life of ice-axes and crampons is necessary to enable future designs both effective and safe. Research is required to establish the stresses, strains and fatigue life of ice-axes and crampons and their relationship with the design parameters of the equipment. The research results will be incorporated into design guidelines for use by ice-axe and crampon manufacturers.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'DNA-origami frame platform for co-evolution ligand selection' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Affinity reagents such as antibodies and aptamers are of paramount importance as tools in biotechnology and the treatment of a wide range of diseases. However, despite their scientific and economAffinity reagents such as antibodies and aptamers are of paramount importance as tools in biotechnology and the treatment of a wide range of diseases. However, despite their scientific and economic impact it remains challenging to systematically generate high-affinity ligands to cover all epitopes of a given target. Here I propose a strategy to provide spatial control over ligand discovery process leveraging the power of in vitro evolution in conjunction with the spatial addressability of DNA nanotechnology methods. Together they form a new discovery platform for the systematic and parallel generation of ligands, specifically aptamers and single-chain Fv antibody fragments (scFv), to provide coverage of epitopes at predefined targets. The proposed strategy exploits cooperative binding (avidity), by co-evolution of the affinity reagents, in the context of a defined molecular three-dimensional framework provided by DNA origami structures. This further expedites structure determination of ligand-target complexes by cryo-electron microscopy (cryo-EM). The combination of rational framework design, in vitro evolution and structural feedback provided by cryo-EM reconstructions will provide a toolbox for the systematic generation of ligands to all accessible epitopes. Our approach also provides a tool for electron microscopy reconstruction of smaller (< 100kDa) biomolecules and their molecular interactions by enhancing contrast and providing context. Once established, this approach will provide a transformational technology platform that enables the parallel interrogation of multidimens
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'ChAlcogenides MEmories for multiLevel Storage' under Sixth Framework.

assistant: **Concept**

The Project aims at demonstrating the feasibility of multilevel storage in chalcogenide-based Phase Change Memories, and at defining material properties, cell architectures and programming conditions to achieve this objective.Chalcogenide-based Phase Change Memories are considered the best candidate to replace Flash memories, beyond the 45nm node. However, in order to maintain the present growth rate in terms of storage densities, and to support the emerging, memory-intensive applications (e.g. video-phones, high resolution pictures, storage of short movies), ways must be found to further increase the storage capability of Phase Change Memories, introducing multilevel storage (two or more bits/cell).The research activity will follow two lines:- Understanding and modelling of phase change mechanism in existing chalcogenide material (GST), including long-term stability of the phases and the factors influencing it. Statistical analysis on large samples will be performed to assess the role of defects.- Investigation of basic material properties, starting from theoretical models, to develop the most suitable material for multilevel storage (new compositions or use of dopants). Sample deposition tests and analysis will be performed in a research environment, taking into account future compatibility with industrial environment.At the end of the project it is expected that the programming conditions and the physical limits of multilevel storage in Phase Change Materials will be available, together with an extended modelling of the phase change mechanism, and an indication of possible material improvements.The final targets of the project include:- a demonstration of multilevel programmability on a Multimegabit test device;- a demonstration of the multilevel performances of the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Workforce Sustainability Testing Platform' (Work-STeP) targeting Horizon 2020.

assistant: **Abstract**

With the proposed Workforce Sustainability Testing Platform (Work-STeP) organisations will have a tool to assess their HR practices with regards to workforce sustainability (e.g. engagement, health, performance).The proposed project will have a profound impact on the European business community. By automating all aspects of the platform, Work-STeP is able to offer its services at affordable rates. Where traditional HR analytics are often too costly for small and medium establishments (SMEs), with Work-STeP SMEs too will be able to assess their workforce sustainability. The project will be embedded in the host institution’s Future of Work Hub and will be supported by its advisory committee consisting of executives from large national and international organisations. The advisory committee, and the PI’s network of organisations from the Sustainable Workforce project will ensure that Work-STeP will be in line with industry demands.In the Proof of Concept phase the team will determine whether and to what extent the platform can use our substantial benchmark dataset from the ERC-Advanced Sustainable Workforce project, in which we investigated what HR investments organisations make and the effects they have on the workforce, in 259 organisations from nine EU countries across six economic sectors. Work-STeP will offer the manager insight in key performance measures of teams within the organisation. Lower team or organisation scores, in comparison with their sector and region, expose areas where there is room for growth in terms of workforce sustainability. These areas of concern, team demographics and the Sustainable Workforce analyses on policy effectiveness allow Work-STeP to offer organisations contextualized advice on which investments to use.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Differential geometry of quantum homogeneous spaces' (DIGEOHOS).

assistant: **Concept**

The research group of A. Joseph at the Weidman Institute is internationally recognized for its fundamental contributions to the theory of Lie algebras and quantum groups. The researcher I.Heckenberger is a member of a group in Leipzig. He has been working on the field of quantum groups with focus on no commutative differential geometry for ten years. In the framework of quantum groups one investigates deformations of universal enveloping algebras of semi simple Lie algebras and quintile coordinate rings of semi simple algebraic groups. One approach to no commutative differential geometry on quantum groups is the notion of covariant differential calculus introduced by S. L. Woronowicz. A powerful method to obtain classification results within the scope of this theory is to determine explicitly the locally finite part of the dual Hop algebra of the quantum group. A. Joseph and G. Letter have answered this question independently of differential calculi. Recently Heckenberger has been investigating differential calculi on quintile irreducible flag manifolds. For classical irreducible flag manifolds the de Ram complex is known to be the dual of the Bernstein--Gland--Gland resolution. The first aim of the research project is to obtain an analogous result in the quantum setting. For this a detailed understanding of higher order differential calculi, generalized Vera modules for quintile universal enveloping algebras and the duality between them shall be established. A second related aim is to evaluate the quantum KPRV determinants pertaining to generalize Vera modules introduced by A. Joseph and D. To Doric in order to describe those exceptional generalized Vera modules whos locally finite endomorphism do not come all from the enveloping algebra. Apart from the Boreal case, s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'SLOVENIAN PRESIDENCY EVENT: LAUNCH OF ESFRI ROADMAP 2021' (MIZS-ESFRI) under Horizon 2020.

assistant: **Objectives**

Proposal concerns the organization of a Launch event of the ESFRI Roadmap 2021 on December 7th 2021 and ESFRI Stakeholder Forum on December 8th in Ljubljana. Both events are a part of the Slovenian Presidency of the Council of the EU in second semester of 2021. The Ministry of Education, Science and Sport (MIZS) will organize the events in close cooperation with ESFRI, StR-ESFRI and the EC, including preparation, broad communication about the events and their outputs and related logistical activities such as venue and technical support, dinner, refreshments and social programme as well as press coverage. The main objectives of the launch event of the ESFRI Roadmap 2021 are to make a formal public presentation of the ESFRI Roadmap 2021, to discuss the outcomes and conclusions of the ESFRI 2021 road-mapping exercise with major stakeholders, to reflect on the main challenges for implementation of research infrastructures, to facilitate a quick start towards implementation for new research infrastructures included in the Roadmap, to reflect on possible actions aiming at long-term sustainability of research infrastructures and to prepare solid ground for the planning of the next ESFRI Roadmap update.The main objectives of the ESFRI Stakeholder Forum are to create a structured constructive two-way communication channel with a broad community of the stakeholders, to contribute to better integration of the RIs in the particular communities and to contribute to improved services of the RIs for specific communities.The objectives of both events will be achieved according to the Work plan, which consists of four Work Packages: WP 1 - Project management, WP 2 - Conference content, WP 3 - Conference organisation & management and WP 4 - Communication, Promotion and Dissemination. Exp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Chromosome self-clearing completes sister chromatid separation'.

assistant: **Objectives**

In this research program, we propose the new concept that sister chromatid separation in mitosis is completed as a result of the dynamic intrinsic structural changes of chromosomes, i.e. through cycles of regional chromosome stretching and recoiling, which we call the self-clearing mechanism of chromosomes. By developing several novel methods, we will establish this new concept and demonstrate that the self-clearing of chromosomes is an essential mechanism allowing complete removal of sister chromatid cohesion, and that it is a fundamentally conserved function from yeast to vertebrates. To maintain genetic integrity, eukaryotic cells must duplicate their chromosomes and subsequently segregate them to opposite poles of the cell, prior to cell division. Cohesion is established between sister chromatids during S phase and marks sister pairs to ensure proper chromosome segregation in the next mitosis. However, the cohesion must be eventually removed to allow sister chromatids to separate and segregate to opposite poles. Although recent studies have revealed how the removal of cohesion is initiated, it is still elusive how this removal is completed. Our project will address mechanisms promoting this process and will open up a new direction of research, regarding dynamic chromosome organization, in particular its compaction and condensation. At present, the structural basis for chromosome compaction and condensation is poorly understood. Our project will shed new light on this inscrutable scientific problem by revealing the process of chromosome self-clearing. The outcome of our research will give important clues to fundamental mechanisms for chromosome segregation and will contribute to our understanding of human diseases, such as cancer and congenital disorders, which are c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'MAXIMISING SUNLIGHT RESOURCES FOR COST, ENERGY AND YIELD EFFICIENT GREENHOUSES' under Horizon 2020.

assistant: **Concept**

Greenhouse agriculture has allowed converting unproductive lands into modern agriculture exploitations, providing an active control tool for moderating the exposure to climate fluctuations and environmental risks, leading to a dramatic increase of crop yields and elongation of the growing seasons. Globally, GHs are concentrated in Asia and the Mediterranean Basin. Excluding China, the world GH coverage can be estimated in more than 450,000 hectares from which not less than 200,000 hectares are located in Europe, mainly in the Mediterranean Basin. However, European GHs are facing a challenge, due to a 40% reduction of food production subsidies in the last 40 years while non-European competitors with lower operational costs are increasing. RUFEPA and SUNBOOST are developing SUN4GREEN with the aim of delivering to GH farmers a dual revenue solution with integrated photovoltaics and crop harvesting to reduce energy costs while targeting high crop yields. This will turn GHs to a stable livelihood by generating a new and reliable electricity income stream in addition to their principal agriculture business. SUN4GREEN will also maximize land use and its productivity by integrating PV systems with GHs in the same land footprint. Greenhouse market is growing at a stable 10% CAGR. Within this market, Smart GH segment is the one presenting major growth, being positioned as a reliable option to increase crop production through LED lighting, HVAC and automatized irrigation systems among other high-tech equipment. In fact, Smart GH market is expected to reach more than €1,060 million with CAGR of 14.18% from 2015 to 2020, having Europe the largest market share among all regions. Furthermore significant number of PV installations have demonstrated its potential to drive economic growt
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Enhanced Framework for Forging Design Using Reliable Three-Dimensional Simulation' in the context of a Fourth Framework call.

assistant: **Objectives**

The objective in the present project is to develop the Finite Element Method to 3D problems for the application as a process and product development and quality assurance system related to metal forming production. The challenge is the implementation of a realistic constitutive law describing the material behaviour and the toolworkpiece interface conditions as regards friction and heat transfer as well as an accurate description of a finite element mesh evolution under large strain conditions. Several teams in Europe are in phase of developing 3D finite element models but they have so far not succeeded to market them due to a lack of reliable automatic remeshing facilities. However for an accurate and economical treatment of forming problems in industry not only a remeshing technique is required. It is also to be adapted and based on an a posteriori error estimation in order to refine the mesh where strain and temperature localisation occurs. The project is of interest to forging industry, material and press manufacturers and to end users such as car manufacturers, aeronautical industry and other mechanical industry. The partnership structure is the following:  Four research laboratories, CEMEF ( France ) material forming center, laboratory of Ecole des Mines de Paris with experience in finite element modelling of material forming processes and development of industrial codes for forging processes simulation, DIMEG from the University of Padova ( Italy ) in studying the materials behaviour in warm and hot forging and physical simulation of ther nal and mechanical events and the interface conditions as regards heat transfer, DTU, the Technical University of Denmark ( Denmark ) with expertise in physical modelling using soft model materials as well as metals, and analysis