RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Integrin signaling' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Research objectives and content Integrins are a family of cell surface receptors, which mediate adhesion of cells to the extracellular matrix. The binding of integrins to extracellular matrix also triggers interacellular signalling pathways that are important for cellular differentiation. The goal of the proposed research is to initiate a characterisation of an integrin signalling pathway in Drosophila, by analysing the function of components at the top and bottom of the pathway: 1) Integrin-linked-kinase, is a kinase that directly associates with integrin cytoplasmic domains, and a Drosophila homologue has emerged from the genome sequencing project. The function of this protein during development will be analysed using molecular and genetic approaches. 2) A gene has recently been identified in Drosophila that is subject to regulation by an integrin signalling pathway. The cis-regulatory regions of this target gene will be characterised to clarify how integrin signalling modulates its expression. Training content (objective, benefit and expected impact) This project will provide excellent training in molecular biological techniques and basic genetics. In the future I plan to apply these techniques to insects with medical and economic importance. Links with industry / industrial relevance (22) This research is not currently linked to an industrial partner. However, the integrins are of great interest to the pharmaceutical industry, so links in the future are feasible.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Development of instantaneous low volume drop measurement device' (NANODROP).

assistant: **Innovation**

Deerac Fluidics' is a leading developer and supplier of nanolitre and microlitre liquid handling instrumentation, which is used in RTD laboratories in the drug discovery, genomic and proteomic sectors. Deerac Fluidics' wishes to use the Marie Curie scheme a s a means to transfer additional skill sets into our organization - in particular expertise in electronic engineering, software, product development and molecular biology. Using these new skills we wish to develop a new platform technology, which would compliment our existing product range.The new platform technology is based on existing intellectual property owned by Deerac Fluidics' and relates to a technology, which can measure in a non-contact manner the volume of a droplet dispensed in real time. Currently there is a significant drive within the high throughput drug discovery, clinical diagnostics, genomic and proteomic sectors for a product of this type as it will allow instant validation of scientific results and will remove the errors, which can cause a significant number of false positives and errors in the screening process. This development would assist in reducing the overall drug development cycle and drug development cost, providing our ageing society with a larger number of beneficial drugs, which have been developed at lower costs.Deerac Fluidics' has extensive technology management experience and will put in place a well-structured project leading to the clear deliverables highlighted below.- The production of a industrially required product bas ed on a new platform technology that will allow us to strengthen our position as a global leader in supplying low-volume instrumentation and to assist in placing Europe as the global leader in nanotechnology innovation.- Embedding new research skills within o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Assessment of nitrogen containing disinfection by-products and their precursors in drinking waters of the Mediterranean Basin' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Disinfection of drinking water is a successful measure to reduce water-borne diseases and protect health. However, epidemiological evidence links bladder cancer to disinfection by-products (DBPs) formed during drinking water treatment. Disinfection with chlorine is relevant in many European countries and previous research has highlighted the need to improve water quality and decrease concentration of DBPs in countries of the Mediterranean Basin such as Spain. In particular, of the many DBPs currently investigated in drinking water, unregulated nitrogen containing DBPs (N-DBPs) are considered among the most toxic ones. Dissolved organic nitrogen, which acts as precursor for these DBPs, is increasing in many drinking water sources due to usage of impaired waters or climate change. Therefore, there is a need for research to prepare water utilities for these changes, evaluate treatment strategies, and consider the need for adaptation to more stringent regulations.The main objectives of this project are:(i) to obtain a database for nationwide occurrence of N-DBPs,(ii) to investigate the effects of existing treatments on N-DBP formation followed by an evaluation at the full and bench scale of drinking water technologies to predict and minimize their formation, and(iii) to identify N-DBP precursors with an innovative mass-spectrometry-based approach so that they can be tracked back to their origin and management at source evaluated.This project aims to transfer the experience and knowledge on DBP science gained in Australia and the U.S. by the incoming researcher Maria José Farré to the Catalan Institute for Water Research (ICRA) which, led by Prof Damià Barceló is one of the European research centers with the highest potential in analytical chemistry and water quality researc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Cryogenic on-chip Levitated Optomechanics for a Spin Entanglement witness to Quantum Gravity' to be submitted under Horizon Europe.

assistant: **Abstract**

This proposal addresses one of the key challenges of modern physics: understanding the interface between quantum mechanics and general relativity. Recently, an experimental test was proposed that can directly witness the need to unify the two theories: observing quantum entanglement between objects that only interact through the gravitational field. A successful test would prove the existence of superpositions of space-time and have far-reaching implications on how we understand our world.So far, no experimental platform exists that can meet the challenging central requirement for this test: A picogram-scale mass in a micrometre-scale spatial superposition with a second-scale coherence time. Here I propose to build such a platform.The objectives of the research are to trap and levitate a picogram mass, cool its centre-of-mass motion to the quantum ground state, couple its motion to a controllable qubit system and, finally, produce and measure a spatial superposition of the mass.Considering all requirements, I identify the unique combination of techniques necessary to achieve this:-  diamagnetic levitation at cryogenic temperatures using on-chip superconducting coils;-  on-chip superconducting quantum interference device (SQUID)-resonator based sideband cooling;-  coupling to solid-state spin qubits.Combining recent microfabrication techniques for chip-based confinement of micro-particles, high-Q resonant circuits and microscopic diamond membranes with spins, it is now possible to realize this system in the lab. My extensive experience with spins and nanomechanical systems as well as microfabrication and low-noise cryogenic measurements, and Leiden University?s infrastructure for vibration-isolated cryogenics supports CLOSEtoQG?s objectives.The research would represent a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Graphene-based nanomaterials for touchscreen technologies: Comprehension, Commerce and Communication'.

assistant: **Concept**

“Enabling Excellence” offers integral R&D training at PhD level around one of the most active and exciting topics at the forefront of nanoscience and nanotechnology, graphene-based nanostructures and materials. We propose a training experience built on three interrelated pillars, namely COMPREHENSION AND CONTROL, COMMERCE, and COMMUNICATION.*Comprehension & Control* covers fundamental knowledge of the nano-objects, the development of functionalities and processing into macroscopic advanced materials and devices, accompanied by a broad set of characterization techniques, to understand the interrelation between local and global properties and the requirements for functional end products.*Commerce* aims at market-ready graphene-based materials and commercial local probe Raman/AFM systems for routine quality control of graphene products. This is accompanied by innovative measures for start-up development and pitching to venture capitalists.*Communication* is the unique keystone in “Enabling Excellence”. The project is a novel experiment to find how best to develop the communication skills in our ESRs, creating optimum conditions under which they are best able to flourish. The results will serve as a model adaptable to European training and research at all levels.“Enabling Excellence” is formed by five partners from academic institutions and four private companies specialized in the above mentioned fields spanning TRL1-9. They offer a common and highly complementary modular structured training programme. During 468 ESR months we will address the need in Europe for nanocarbon specialists, training a new generation of highly skilled interdisciplinary clear thinking researchers. We will develop in these young people creativity, confidence and the ability to communicate with the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Electronic Health Record systems for Clinical Research' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Current medical needs, the growth of targeted therapies and personalized medicines, and escalating R&D costs result in formidable cost pressures on healthcare systems and the pharmaceutical industry.  Clinical research is also growing in complexity, labour intensity and cost.  There is a growing realization that the development and integration of Electronic Health Record systems (EHRs) for medical research can enable substantial efficiency gains, make Europe more attractive for R&D investment and provide patients better access to innovative medicines and improved health outcomes.EHRs can now be designed to seamlessly integrate with existing research platforms and healthcare networks to create opportunities for many stakeholders, including the pharmaceutical and bio-pharma industries.  However, key challenges are compliance with various ethical, legal and privacy requirements (and acceptance by the general public, patients, and medical professionals), providing a platform that works across many EHR systems and is sustainable within a scalable business model.A 4-year project, EHR4CR will involve a team of recognised European academic and industrial partners.  The project will build a platform to enable the use of EHR for more efficient medical research and run pilots (on interoperability, security, data quality, data storage solutions, organisational issues, accreditation and certification, etc) to demonstrate the viability and scalability of an EHR4CR business model.The EHR4CR project supports the IMI strategic agenda with an information gateway solution to enhance clinical research efficiency and innovation.  A key IMI aspect is the development of a knowledge management capability that can, for example, provide information management support for other research on person
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'LUMinous ElectroNic TILE' (LUMENTILE).

assistant: **Innovation**

LUMENTILE originates from an idea of disruptive innovation, where the joint use of new technologies creates added value and new functionalities for traditional materials, thus turning the classical ceramic tile into a “multifunctional electronic luminous tile” realized by large area and organic electronics. LUMENTILE can be also considered as design-driven innovation, where we give a different meaning to the use of light driven by the design, by empowering it to be used as a radical different designed element for architecture, as a skin integrated element for interior design, lighting or advertising purposes.The demand for aesthetically integrated and creative construction elements is steadily increasing in many areas of business and industries. A growing number of designers, architects and industrial manufacturers across the world share a common interest in having new elements capable to create surfaces or coverings as creative and multifunctional solutions. LUMENTILE aims, on one side, to fill the gap between a simple construction element and a luminous surface element, and gooes far beyond, by developing a cutting-edge technologic module (the luminous electronic tile) that is capable of displaying lights, colors and images that can be used as a chameleonic display to be employed as a skin for horizontal (floor) or vertical (wall) applications. The final product will be an “on-the-fly” high energy efficient device that can be considered as a sustainable and competitive lighting element. On the other hand, the possibility of adding other sensors internally to the electronic tile enables it to increase the above mentioned properties (such as the detection of people walking onto it) and also to empower other creative or multifunction purposes. This project will address t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Sustainable Mixed-ion Layered Perovskite Solar Cells' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

We propose to create and investigate new types of organic-inorganic perovskite materials for low-cost solar cells. The state-of-the-art perovskite based solar cells employ MAPbI3, which has raised concerns over the potential toxicity of Pb. The strategy of the MPerS project is to create, investigate and optimise  sustainable  perovskite materials for solar cell application. More than one types of metal and organic ions will be introduced in the perovskite structure to realize  layered materials which are expected to exhibit both excitonic and free carrier behavior with enhanced stability. Thin films of the new materials will be characterized using several techniques, e.g. Xray diffraction. THz, Time resolved emission spectroscopies, EBIC will be used to understand the generation and dynamics of charge carriers in the materials and across interfaces. Development of solar cells will be carried out with an aim to reach 15% power conversion efficiency employing a non-toxic absorber. This highly interdisciplinary project that spans the field of chemistry, condensed matter physics,  electronics and engineering is conceived on basis of the combined expertise of the host and the applicant and state-of-the-art infrastructure at the UOXF. A secondment at Oxford PV will test the commercial viability of the project. This project addresses Horizon 2020’s goals on clean and sustainable energy and the EU’s concern on toxicology of Pb . Completion of the project will open up new areas in low-cost electronic materials with wider impact and improve EU’s competitiveness in materials research. While the applicant will get an opportunity to learn new experimental skills in condensed matter physics and spectroscopy and benefit from industrial exposure. UOXF will benefit from the applicant by
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Road-mapping study of CBRNE demonstrator' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The CBRNEmap will address the cross-cutting activity of the becoming CBRNE Demonstrator using a holistic approach, putting end-users, industrialists and other stake-holders together with members of the S&T community in the front seat from the start of the activity. The CBRNEmap will evaluate the complex matrix of temporal events (before, under and after), against sectors (law enforcement, Civil protection – rescue and Health together with such processes as e.g. Boarder control, Mass Transport), taking in consideration that each of the letters CBRNE, may have its own aspects of vulnerabilities, priorities and possible solutions. These generic needs will be matched by advanced technological solutions integrated at the system of systems level to become the CBRNE Demonstrator. The CBRNE Demonstrator road-map for development of technologies and systems will take into consideration all present and past activities and search for generic solutions of technologies relevant to the full European setting at both the societal and individual level. Furthermore, it will consider all aspects prior to production (remaining development, IPR, market and more). The phase 2 project has eventually to produce a product, a prototype or a demonstrator of value to all EU 27. CBRNEmap will prioritise demonstration tasks based on systematic analysis of end-user requirement and comprehensive reviews of available CBRNE S&T investments. The final roadmap will be developed for an optimised demonstration programme based on a Concept Development & Experimentation (CD&E) approach. Interlinked with developing the road map for the CBRNE demonstrator is the analysis of gaps and needs in CBRNE research. A stake holder signed suggestion for future research investments will be an important delivery of CBRNEmap
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Sustainable production of mud crab scylla sp. through stock enhancement in mangroves' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

The main objectives are defined as follows :* To develop mud crab broodstock maturation system, which promotes consistent spawning of good quality larvae: optimisation of hormonal implant, eyestalk ablation and feeding regime.* To standardise hatchery production of Scylla serrata by improving zootechnics, feeding regime and microbial conditions : promotion of consistent and increased survival rates and quality postlarvae.* To assess survival and growth rate of cultured vs. wild crabs after tagging and (re-) release, and evaluation of a sustainable technique for the cultivation of mud crab.* To use recapture data to estimate population densities of wild mangrove crabs and measure impact of fishery effort.* To include on above estimates of the effect of selective fishing on wild stocks e.g., fishing for juveniles for pond culture, immature for fattening and adults for marketing.* To measure migrations and movements of (re-) released juveniles throughout the life cycle and compare with cultured juvenile release.* To produce in hatchery different age or performance classes and assess survival and growth after release to identify most suitable groups for restocking purposes.* To reduce costs for production of juveniles at economic scale under local backyard conditions.Expected Outcome1. A standard technique for mud crab broodstock maturation2. A standard hatchery technique for production of mud crab postlarvae3. A standard tagging technique for crab species4. Mud crab population study in a defined area, including the impact of fisheries5. Study on the impact of restocking on population characteristics of mud crabThe key activities involve :* An experimental study on stock enhancement of the mud crab Scylla serrata and the possible impact of fisheries on it. Therefore, a spec