RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Compit' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

The scientific/technological objective is a faster dissemination of progress in advanced Information Technologies in the maritime industries and cross-fertilization between suppliers and operators of maritime structures (ships and offshore platforms). Advanced techniques are e.g. virtual prototyping /virtual reality, artificial intelligence (e.g. expert systems), machine learning (e.g. neural nets), robotics and Internet use. The industrial challenge is managing a growing integration of systems while improving at the same time user-friendliness and distributed concurrent engineering.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Tradable renewable certificate know-how and initiatives network' (TRECKIN).

assistant: **Concept**

Background Tradable Renewable Certificate (TRC) systems have been developed in several countries (particularly in Europe, USA and Australia. TRC-systems provide a robust mechanism for tracking and verification and they potentially offer an efficient and flexible economic tool.The TRC-systems that are currently being developed are bottom-up approaches, which are not mutually harmonised. Little is known about system-details, other than by those who have initiated them, although a huge amount of information is available.Aims: The aim of the project is to disclose available TRC-know-how for governments and the private sector, in a structured way, by joining the forces of the current TRC-networks in an international network.Sub-goals of the project are:(1) acceleration of access of developing countries and economies in transition to the network,(2) answering of major TRC-questions by means of specific research
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Adapting to Global Change in the Mediterranean hotspot: from genes to ecosystems' (ECOGENES), addressing dissemination and exploitation.

assistant: **Impact**

The Doñana Biological Station (EBD-CSIC hereafter) was created in 1965 and is committed to carry out research on ecology and biological diversity, encompassing natural history, evolution, ecology, systematics, biogeography, genetics and conservation biology. Our major tasks are the understanding of the processes that threaten biodiversity in the face of Global Change, the development of tools for the analysis and prediction of social and environmental consequences and the assessment of feasible solutions for society. This requires an integrative approach combining multiple tools and theoretical frameworks. To cope with such a challenge, we need an increase in novel technical approaches such as massive modelling and genotyping that may improve our prediction capacity. This knowledge is applied to the management and conservation of biodiversity in all its forms. Our proposal is aimed at reinforcing our capacity in order to maintain our ability to serve the Society of Knowledge by creating a cooperation platform where all similar institutions of Europe, but particularly those of the Mediterranean region, could exchange experiences, share standards and data, and promote training of experts to deal with the threats posed by the impact of Global Change. We have selected analytical tools highly demanded by our stakeholders and managed by all our research lines: Genetics and Genomics, Ecological Modelling and Ecophysiology. These new approaches will be (1) introduced in our running projects by eight newly recruited researchers experienced in these areas, (2) discussed in international meetings, conferences and congresses, (3) the drivers behind the secondments of researchers of our centre and those of 5 collaborative centres and (4) the subject of several training exchange acti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Investigating the link between centrosomes, stem cells and cancer' (CENTROSTEMCANCER) targeting Seventh Framework.

assistant: **Abstract**

Centrosomes are cytoplasmic organelles found in most animal cells with important roles in polarity establishment and maintenance. Theodor Boveri s pioneering work first suggested that extra-centrosomes could contribute to genetic instability and consequently to tumourigenesis. Although many human tumours do exhibit centrosome amplification (extra centrosomes) or centrosome abnormalities, the exact contribution of centrosomes to tumour initiation in vertebrate organisms remains to be determined. I have recently showed that Drosophila flies carrying extra-centrosomes, following the over-expression of the centriole replication kinase Sak, did not exhibit chromosome segregation errors and were able to maintain a stable diploid genome over many generations. Surprisingly, however, neural stem cells fail frequently to align the mitotic spindle with their polarity axis during asymmetric division. Moreover, I have found that centrosome amplification is permissive to tumour formation in flies. So far, however, we do not know the molecular mechanisms that allow transformation when extra centrosomes are present and elucidating these mechanisms is the aim of the work presented in this proposal. Here, I describe a series of complementary approaches that will help us to decipher the link between centrosomes, stem cells and tumour biology. In addition, I wish to pursue the original observations made in Drosophila and investigate the consequences of centrosome amplification in mammals.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project '(Re)Constructing the Archaeology of Mobile Pastoralism: bringing the site level into long-term pastoral narratives'.

assistant: **Objectives**

CAMP investigates long-term pastoral dynamics in drylands, by developing an innovative and reliable methodology to study archaeological pastoral sites. Pastoralism has been recently endorsed by the FAO as a successful strategy to achieve food security by efficiently exploiting the inherent variability in natural resources. Modern pastoral systems represent the legacy of animal domestication processes that started before the beginning of the Holocene. However, our understanding of ancient pastoralism is hampered by the lack of a proper methodology that can overcome the ephemeral evidence that characterize pastoral sites. CAMP will pave the way, through methodological innovation, to a more thorough investigation of past adaptation to dryland environments. Highly controlled data on the anthropic markers for pastoral activities (chemical multi-element by portable X-Ray Fluorescence, phytoliths, organic residues and isotopes) will be collected in pastoral ethnographic settlements and analyzed to create models that will then be used to interpret the archaeological evidence. CAMP will advance research in: (a) methods and theory in the archaeology of pastoralism; (b) anthropic activity markers and the use of pXRF in archaeology; and (c) adaptive strategies in drylands. This project is a unique opportunity to strengthen the study of pastoralism by providing a widely applicable methodology that can augment our knowledge on past human adaptation to drylands and inform the design of sustainable and historically-grounded development strategies for pastoral futures. CAMP methodology will be potentially exportable to other archaeological sites, independently of their chronology, cultural or geographic context, representing an invaluable advance to archaeological methods at large.


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system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Higher-loop amplitudes on the sphere: a new approach to the perturbative expansion of quantum field theories'.

assistant: **Concept**

Almost all we know about particle physics and the Standard Model comesfrom scattering experiments and our ability to predict them viascattering amplitudes (these measure probabilities of scatteringprocesses). To meet the impressive technological advances of particlecolliders like the Large Hadron Collider at CERN, new tools andconcepts have emerged over the last 25 years. More than givingmethods, they have triggered a revolution in our understanding of theformal microscopic structure of particle physics, a subject peoplethought they knew everything about.My program is based on a set of formulæ due to Cachazo, He & Yuan(CHY), that challenge the way we think about scatteringamplitudes. They relate to 'twistor' ideas and string theory. Theformer aims at manifesting the geometry of field theories, but failedso far to grasp their quantum-ness. The latter, in spite of itsmathematical beauty, has the drawback of having additionalcontributions that are hard to decouple from the field theoryones. The CHY formulæ retain the advantages of both methods, and leadto a variety of remarkable expressions for scattering amplitudes in aincreasing number of theories, including gauge, gravity and scalartheories.In a crucial work, I showed that these methods actually carry over tothe first quantum correction: this was the first time ever thattwistor methods were shown to work at the quantum level. My projectaims to extend this and reformulate the full pertubative quantumexpansion of field theories in the CHY language. This would be a majorconceptual advance. I explain that to do so will require to understanda more fundamental object called Null String, whose quantization willshed light on my 'quantum CHY formalism'. I also propose applicationsof the formalism of interest for LHC physic, like
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Nano-particle based enhancement of composite and thermoplastic materials'.

assistant: **Concept**

ANF Development proposes to develop applications for its nano fiber Nafen, that will include Nafen-modified thermoplastics and Nafen-modified composite materials. The new nano materials will possess superior mechanical properties, which will allow weight reduction and durability increase for polymer finished products and replacement of traditional materials from their applications. ANF will sell to the polymer-processing industry worldwide.ANF will address key challenges in using nano materials for polymer modification: difficulty to access nano fiber, which would give effect at low loadings and at the same time can be industrially available at low cost. Existing nano materials, which are currently used for this purpose, are either unavailable on large scale (single wall CNTs) or require high loads in polymer (multi-wall CNTs, nano silicas, nano clays).ANF will install pilot production facilities for modified thermoplastics and modified composite materials, increase the capacity of Nafen production facility, prepare Nafen masterbatches in thermoplastics and composite materials and test masterbatches in house and at the production sites of industrial co-development partners. After that commercial contracts with interested partners will be signed.With this solution, for the first time, applications will be developed for unique crystalline nano fiber Nafen, which is industrially available at low cost and can be used at low loadings (<1%) in polymers. This makes it possible to (1) achieve polymer goods weight reduction by using less material or making more durable goods (2) achieve fuel economy over the lifecycle of airplanes and vehicles (3) replace traditional materials from their applications. ANF receives several inquiries a week from various polymer industry companies
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Cosmological Structure Formation in the Multiverse' to be submitted under Horizon 2020.

assistant: **Abstract**

This application proposes a programme of research directed at the outstanding puzzle of modern cosmology: the strangely small non-zero value of the vacuum density.  This can be approached in three ways: (1) Evolution; (2) Revision of gravity;(3) Observer selection in the multiverse.  The first two of these can be addressed by ongoing and future large galaxy surveys.  Part of the research programme is directed at new ways of assuring robust measurements from these surveys of the main diagnostics of interest -- the effective equation of state of dark energy and the growth rate of density fluctuations. This will exploit and extend current work on systematics of galaxy properties as a function of large-scale environment in the cosmic web.But so far such tests show no deviation from standard gravity and a cosmological constant. This fact drives interest in a multiverse solution, in which different causally disconnected domains may be able to possess different effective cosmological constants.  This research will concentrate on the astrophysically interesting question of how galaxy formation would be affected by different levels of vacuum energy. This previously been addressed only by oversimplified analytic arguments, and it is possible that the exponential sensitivity of galaxy formation efficiency to the vacuum density could be very different to the simple estimates. Current claims that the multiverse approach predicts the right level for the cosmological constant would then be disproved.  In any case, there is much of interest to be learned regarding the robustness of current theories of galaxy formation by 'stress-testing' them outside the rather restricted parameter regimes normally considered. The result will be a deeper understanding of the assembly of cosmic structur
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'European strategy for antibiotic prophylaxis in surgery and intensive care'.

assistant: **Objectives**

Improvement of quality of care has been on the agenda in European health care institutions for some time. Improving the quality of care is one of he most comprehensive tasks that can be undertaken engaging both aministrative and medical staff. Implementation of this intention should be based on systematic monitoring with feedback and evaluation. The information gathered for this purpose must however be professionally meaningful, of good quality itself and not too costly to obtain. Current litterature shows that many different strategies exist for the use of prophylactic antibiotics to prevent postoperative wound infections in surgical patients and pneumonia in intensive care patients. The incidence of prophylaxis used in apparently comparable surgical interventions ranges from well above two thirds to one third, and the variety of antibiotics is also wide. In intensive care the use of SDD in Europe was recently found to vary between countries ranging from 80% of the units in some countries to 0 in others. Within the field of infection control the use of clinical monitoring systems has advanced to a point where unqualified applications should be avoided, and the time has come where the focus should be on developing relevant indicators. The project applies the essence of this experience to examine antibiotic prophylaxis in a sample of surgical and intensive care patients, and includes validation techniques to ensure comparability of data. A guideline on good antibiotic prophylaxis (GAP) as well as indicators fo verification of GAP are supposed to emerge from the study, which may act as a precursor to a forthcomin European standard in hospital infection control. The intent of the study is to uncover strategies for prophylactic antibiotic treatment in surgery and intensive
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Centre for ultrafast science and biomedical optics' to be submitted under Fifth Framework.

assistant: **Abstract**

Description:The Centre for Ultrafast Science and Biomedical Optics (CUSBO) is a facility within the field of lasers, optics and spectroscopy. Research is performed on ultrafast lasers, non-linear optics, high intensity laser-matter interactions, ultrafast processes in quantum confined materials, non-invasive optical characterisation of biological tissues and broad band fluorescence lifetime spectroscopy. CUSBO covers quite a broad range of activities of interdisciplinary nature, which rely on the most advanced technologies in the laser field. State of the art laser sources provide features such as pulse duration below 10 fs with either high peak power or wide tunability from the visible spectrum up to the soft X-ray region. These optical probes represent the frontier in the ultrafast technology. Time-resolved techniques can be applied to the field of biomedical optics, based on state of the art instrumentation for the non-invasive optical characterization of biological tissues. Time-resolved systems for broad band spectroscopy of diffusive media and time-gated techniques provide unique tools for studying absorption and scattering spectra of living tissues and for fluorescence lifetime imaging.Application:Users are asked to send their proposals to the Project Manager of CUSBO by e-mail. The proposal should contain a summary (two pages), which must include a description of the research, the needs in terms of equipment and the expected amount of time for the experiments. A list of the researchers involved in the experiment should also be provided. The proposals will then follow the selection procedure.Project Manager:Prof. Sandro De Silvestri, Dipartimento di Fisica, Politecnico di Milano, Piazza L. da Vinci 32, 20133 Milano - ItalyTel: +39-022-3996151Fax: +39-022-3996126E
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'SUGARSmart: Smart design of recombinant antibody fragments specific for carbohydrate molecules' (SUGARSmart) targeting Horizon 2020.

assistant: **Abstract**

The development of new approaches to explore the diverse role of glycans in normal and physio- pathological conditions of the cell is a major challenge. Our previous research recognized roles of anti-glycan recognition molecules (lectins and antibodies) in the diagnosis of diseases like cancer, immunity, and hyperacute rejection upon bioprosthetic transplantation etc. However, because of the structural complexity, well-established approaches for developing glycan-based therapeutics are limited.To address this issues, SUGARSmart aims to develop a workflow for rational design of single-chain fragment variable (scFv) antibodies to enhance glycan recognition capabilities, both specificity- and affinity-wise (improving detection limits of assays). Three major aims will be pursued: First, we will apply molecular modeling to predict mutations which lead to enhance affinity and specificity of anti-αGal scFv. A range of mutational strategies will be tested in order to learn which scFv domains, which particular locations (functionally important sites), and which mutations (aromatic or polar) are best suited to improve affinity and specificity. Second, computationally predicted mutants will be obtained by mutagenesis or chain shuffling. Validity of the predictions will be tested by affinity-measurement (ITC/SPR), array techniques and ELISA. At the end, validation of computational models of scFv-glycan interactions with experimental techniques will enable us to propose a workflow to engineer other anti-glycan scFv antibodies. Overall, this project proposes an interdisciplinary approach to enhance our ability to quantify and engineer glycan recognition molecules having potential application in the smart and tailored development of future diagnostic reagents and therapeutics. To the