RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'European Eddy-RIch ESMs' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Eddy Rich Earth System Models (EERIE) will develop a new generation of Earth System Models (ESMs) that are capable of explicitly representing a crucially important, yet unexplored regime of the Earth system, the ocean mesoscale. Leveraging the latest advances in science and technology, EERIE will substantially improve the ability of such ESMs to faithfully represent the centennial-scale evolution of the global climate, especially its variability, extremes and how tipping points may unfold under the influence of the ocean mesoscale. Model improvements include new dynamical cores, new components (particularly sea ice), scale-aware parametrization and the complementary use of Machine Learning (ML) The technological challenge associated with this ambition is very high. EERIE’s goal is to achieve a simulation speed of up to 5 simulated years per day (5 SYPDs) and to make efficient use (reduction in power consumption by 50%) of the pre-exascale supercomputers now available in Europe. The technological solutions that are to be leveraged in EERIE are the use of reduced precision, GPUs, ML and reduced I/O. Alongside model improvements, EERIE will develop innovative experimental simulation protocols that are suitable for the mesoscale, to be pioneered on behalf of the global climate modelling community, in preparation for the next IPCC. EERIE will produce useful and usable climate information that will contribute to national and international climate change assessments such as IPCC; it will incorporate model variability and extremes within an Integrated Assessment Model (IAM) via a MLemulato;, and it will deliver storyline approaches to the consequences of climate tipping points and disease outbreaks.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Magneto-ionic data-security device integrated on flexible substrates' (SECURE-FLEXIMAG) under Horizon Europe.

assistant: **Objectives**

Traditional methods of safeguarding data often fall short in today’s rapidly evolving information technology landscape. Passwords are vulnerable to hacking, and while encryption offers enhanced security, it significantly increases data processing costs and slows performance. Storing secret keys in battery-backed memory is also inefficient in terms of energy consumption. The advent of physical unclonable functions (PUFs), which create unique device fingerprints based on random physical properties, marked a significant leap in hardware-level data security. Despite recent progress in PUF technology, challenges such as energy efficiency, cost, scalability, randomness, and reconfigurability remain. Overcoming these hurdles requires innovative materials and designs. SECURE-FLEXIMAG aims to strengthen data security and promote technology transfer by building on the PI's recent research in three key areas: (i) magneto-ionics, (ii) exchange coupling to lock access to data and (iii) stochastic magnetization reversal phenomena in arrays of  magnetic dots. These effects can be synergistically combined to develop an advanced data-security device that will largely surpass conventional password methods and current PUF approaches. The project will explore market prospects and business development strategies in collaboration with various stakeholders and potential end users.


**Keywords:** magneto-ionics, magnetic, energy efficiency, data security, physical unclonable function
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Steering organic farming transition' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

A key challenge for sustainable intensification of agriculture is to reduce hunger and poverty by producing increasing amounts of food, feed, and bioenergy for a growing world population, but with minimal loss of biodiversity and ecosystem functioning. In intensive conventional farming systems yields are high, but soil biodiversity and ecosystem functioning are often reduced, and soil food webs are simplified. Organic farming provides a more environmentally sustainable alternative, but it typically produces lower yields, particularly in early years after conversion. In SOFT (Steering Organic Farming Transition), I will test if soil inoculation may be a promising tool to speed up the transition from high-yield conventional to high-yield organic agriculture and can help to overcome ‘soil legacy effects’ due to impoverished soil communities. First, I will use a chronosequence of farmers’ fields throughout The Netherlands that have been converted from conventional to organic farming to study the role that the structure of soil networks may have in soil functioning. Then, I will use soil collected from these sites to test the potential of soil inoculation to aid the transition of soil communities and coupling of soil networks in organic farming systems. By revealing the potential of whole soil inoculation to regenerate soil networks, and how soil networks relate to functioning in agroecosystems, SOFT will be a ground-breaking advancement compared to current efforts to understand the transition from conventional to organic systems and may serve as a baseline for downstream manipulation studies in which certain soil communities may be engineered as inoculants to steer and speed-up this transition. Taken together, SOFT will contribute to establish new management practices that
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Development of dendritic cell-targeted lentivirus vectors for vaccination' under Sixth Framework.

assistant: **Concept**

Dendritic cells (DCs) are one of the key antigen presenting cells from the immune system to mount effective immune responses against pathogens and tumours. Several approaches for clinical trials involving this cell type are currently under study, including cellular vaccination using DCs loaded with both pathogen and tumour antigens.However, these procedures, although providing promising results, are nowadays expensive and difficult to standarized. Therefore, this project will employ a rational design approach to the development of new vaccine vectors, by engineering lentivirus vectors specifically targeted to dendritic cells (DCs).For this purpose, single chain antibodies (scFvs) specific for dendritic cells will be constructed from a phage display library. DC-specific scFvs will be fused to the MLV-A envelope protein through a blocking peptide followed by a matrix metalloprotease (MMP) recognition sequence. Lentivirus vectors based on defective HIV-1 genomes will be produced from stable packaging cell lines expressing DC-targeted chimeric scFv-MLV envelopes.Transduction specificity and efficiency will be assayed both in cell cultures and in vivo. Antigens of interests will be expressed alone or co-expressed with DC-activating molecules, and immune responses against these antigens will be measured.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Digitising Smell: From Natural Statistics of Olfactory Perceptual Space to Digital Transmission of Odors'.

assistant: **Innovation**

This proposal is framed by a technological goal: We aim to digitize smell. Achieving this is currently prevented by gaps in basic science. We aim to fill these gaps, culminating in a proof of concept for our model. The primary gap we identify is lack of data on what humans typically smell. Phrased conceptually, in Aim 1 we ask what are the natural statistics of human olfactory perceptual space. We address this in a series of three experiments, highlighted by one where we equip participants with a wearable sampling apparatus we designed and built for this proposal. The apparatus measures sniffing behaviour to identify odor sampling, measures neural activity to verify olfactory perception, takes video of the visual scene, analyses total levels of volatile organic compounds in real time, and collects odor samples for detailed analysis off line. In other words, we generate an olfactory equivalent of Google Street View, with the addition of chemical, perceptual and neural data. Using this we will characterise the natural statistics of human olfactory perceptual space. Moreover, a major contribution of this proposal will be in posting this massive data as a publicly available recourse. Next, in Aim 2 we will use this data to digitize human olfactory perceptual space. We build on a model that allows us to recreate odors using a restricted set of odor primaries. We will test our model in two frameworks: One we call SmelloVision, where we develop the algorithmic framework to generate an odor to match any digital image, and one we call TelleSmell, where we develop a device to sense the environment, the algorithmic framework to transfer the data, and a device to generate the corresponding odor remotely. We provide pilot data for Aim 2 where we sensed an odor in Mainz (Germany), tr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'CSIC Doctoral Network in Synthetic Biology: Engineering Biomolecular and Cellular Systems.'.

assistant: **Objectives**

SYNBIO-CSIC (CSIC Doctoral Programme in Synthetic Biology: Engineering Biomolecular and Cellular Systems) is a new, cutting-edge doctoral programme led by the Spanish National Research Council (CSIC) and coordinated through the Margarita Salas Biological Research Centre (CIB-CSIC). It aims to recruit 20 doctoral researchers to provide them with a new dimension of training through highly interdisciplinary & intersectoral research in Synthetic and Engineering Biology under three major thematic areas (bottom-up, top-down, and computational synthetic biology): from fundamental studies to translational solutions in sustainability and health. The programme operates under the principles of Open Science and maintains the highest research quality standards.  It represents a stepping stone towards the implementation of a long-term collaborative agreement in the frame of the CSIC Hub for Synthetic Biology through a multidisciplinary and innovative approach. SYNBIO-CSIC includes 50+ options for research projects with prestigious supervisors and the availability of world-class research infrastructures. The recruited fellows will benefit from an outstanding training programme that combines research-oriented and demanding soft skills, including practical hands-on-schools, training in research diversity and scientific & communication skills, and a retreat for personal development. The collaboration with several Associated Partner organizations, including Universities, private companies, and research centres, further enhances the international & intersectoral aspects of the programme. Altogether, SYNBIO-CSIC offers the perfect environment for training doctoral researchers in synthetic biology and related disciplines, thus creating many future opportunities for doctoral fellows and a sou
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'New perspectives for prion therapeutics (TSE THERAPEUTICS)' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

During the last decade, research on Transmissible Spongiform Encephalopathies or prison diseases have taken a new dimension since the Bovine Spongiform Encephalopathy crisis in Europe and the emergence of a new variant of Creutzfeldt-Jackob disease in humans. It is likely that bovine prison was transmitted to humans through consumption of tainted beef product, which represent s a serious threat for general health in Europe. Although therapeutic approaches of these diseases are being developed for decades, these efforts have not yet lead to successful therapeutic interventions. It is our assertion that there is an urgent need for an international Conference aimed to sum up the scientific data available on prison therapeutics, to share the new perspectives on this topic and, to look at therapeutic trials in Tees.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Production of Cyclic Carbonates from CO2 using Renewable Feedstocks' (CYCLICCO2R).

assistant: **Concept**

The concept of CyclicCO2R is to create a process that removes the dependency on fossil fuel and increases the energy efficiency to create a net CO2 uptake in the production of cyclic carbonates. This objective will be reached by basing the process on the use of renewables and CO2 in the production of cyclic carbonates. Two routes will be explored: 1) production of glycerol carbonate methacrylate from epichlorohydrin and CO2 and 2) production of propylene carbonate from propylene oxide and propylene glycol with CO2The focus will be on:1) Development of the optimal catalyst-process combination both in activity, catalyst recoverability and optimal immobilization technique;2) Intensification of the reactions in a flow reactor focusing on energy efficiency and increased product yields;3) Creating a miniplant scale process which starts with the renewable raw materials and CO2 and produces cyclic carbonates;4) Completion of designs and engineering of a scaled-up process integrated with a chemicals plant so that the developed technology is directly transferrable to industry;Furthermore the feasibility of using CO2 in combination with water to produce intermediates of the cyclic carbonate production directly will be evaluated (currently photocatalytic and electrocatalytic processes with a high selectivity, but a low yield). If this is possible, in the future, the production of cyclic carbonates from CO2, water and energy (available at the same location) will become possible. It will increase the CO2 utilisation in the production of cyclic carbonates.The proposal will create a new industrial process in which renewables and CO2 are used to create value products and reduce GHG emissions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Intermodal Information Link for Improved Logistiks' to be submitted under Fourth Framework.

assistant: **Abstract**

Identified roles for each actor in the transport chain;Determined need for information exchange between the actors;New or adapted existing (EDI) messages;Identified constraints and prerequisites for the information exchange;Rules for the exchange of information;Demonstrated IT solutions in the form of generic model;Input for harmonisation. %STORA and Avesta Sheffield export via GothenburgSTORA - Greece, warehousing and distribution %Results from projects within the running Framework Programme, e.g. EUROBORDER, IPSI, INTERPORT, BOPCOM etc will be integrated. INFOLOG will co-operate with PROSIT and COBOLT and also liaise with standardisation activities within CEN, mainly TC278 and UN/EDIFACT
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'A future for the Dead Sea basin: options for a more sustainable water management'.

assistant: **Innovation**

The Dead Sea Basin has been affected by the economic and demographic changes of the last 50 years: a visible symptom for the degradation is that the surface area of the Dead Sea has shrunk by about 30 %. The objective of this project is to establish the scientific basis for a more sustainable than today" water management and water-related land management in the Dead Sea Basin. The proposed research includes both the physical and social dimensions. The approach is to synthesize the available data, to analyse the interactions between natural resources and human activities, to project likely development trajectories and their impacts, and to establish strategic more sustainable development plans, and from this, to develop practical recommendations that can be used for strategic decision making."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Nuclear magnetic resonance spectroscopy of liquid-liquid phase separation' (LLPS-NMR).

assistant: **Innovation**

Liquid-liquid phase separation (LLPS) is a phenomenon inherent to the thermodynamics of liquids, is critical for the development of technologically useful fluids and underlies some of the biggest health changes in our society. LLPS is based on transitions between two different forms of liquid that have the same chemical composition, but distinct energy, entropy and density. Despite the importance of LLPS for technology and health, however, only a very low-resolution view primarily through light microscopy is currently available for LLPS states formed by peptides and proteins. Because of this bottleneck, the interactions, which stabilize liquid droplets, and regulate their biogenesis, as well as a rationale for the biochemical function of LLPS, have remained mysterious. To tackle this massive unmet need, I propose to develop powerful methods of NMR spectroscopy that go far beyond the state-of-the-art and team them up with mechanobiology/force microscopy to break the resolution barrier of polypeptide LLPS and push the description of the internal organization of liquid droplets from micrometer to sub-nanometer. Although highly challenging, the novel methods when successful will (i) disentangle the structure and kinetics of intrinsically disordered proteins within LLPS reaction chambers in space and time, (ii) unravel the nature of chemical reactions in liquid droplets, and (iii) decipher LLPS regulation by posttranslational modifications, nucleic acids and critical changes in cellular environment at atomic resolution. The innovative nature of the proposal is designed to unravel the innermost forces in liquid droplets and to transform our knowledge about the chemistry of liquid phase-separated protein states. Findings from this proposal will provide critical guidance in the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The response of Arctic Ice Masses to Climate Change Modelling, Remote Sensing and Field Measurements' (1994-1998) under Fourth Framework.

assistant: **Objectives**

In the future, governments will require increasingly sophisticated information on possible future sea level changes as input to the policy making process. The IPCC has identified the polar ice sheets to be the largest source of uncertainty in explaining the present rise in global sea level. The aim of this proposal is to predict the sensitivity and response of Arctic glaciers and ice caps to climate change over the next century, together with the associated implications for global sea level. The programme has the following major objectives: 1. To use energy balance models on a representative set of ice masses in the Eurasian Arctic sector to predict their response to an envelope of future climate change scenarios. The deliverable product of this work will be quantitative predictions of glacier mass-balance and sea-level change at the century timescale. For the energy balance modelling to be undertaken successfully, a number of observed parameters are required to provide (a) boundary conditions and (b) independent datasets to test model performance. 2. To use a combination of field and satellite remote sensing data from Arctic glaciers to calibrate and test these models. Field data include meteorological and mass balance observations, and airborne and ground measurements of ice surface elevation, thickness and volume from radar studies. Satellite remote sensing data include measurements of ice-surface reflectance or albedo, the shifting position of the snowline, and the rate of mass loss through iceberg production. Our main field study areas are in the Eurasian Arctic sector which, due to its location at the extremity of the oceanic currents and cyclone tracks transferring heat northward through the North Atlantic, is a highly sensitive part of the Arctic climate system.