RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'How nature's smallest clouds slow down large-scale circulations critical for climate' (CloudBrake).

assistant: **Concept**

Do even the smallest clouds simply drift with the wind? Vast areas of our oceans and land are covered with shallow cumulus clouds. These low-level clouds are receiving increased attention as uncertainties in their representation in global climate models lead to a spread in predictions of future climate. This attention emphasizes radiative and thermodynamic impacts of clouds, which are thought to energize the large-scale Hadley circulation. But broadly overlooked is the impact of shallow cumuli on the trade-winds that drive this circulation. Reasons for this negligence are a lack of observations of vertical wind structure and the wide range of scales involved.My project will test the hypothesis that shallow cumuli can also slow down the Hadley circulation by vertical transport of momentum. First, observations of clouds and winds will be explicitly connected and the causality of their relationship will be exposed using ground-based and airborne measurements and high-resolution modeling. Second, new lidar techniques aboard aircraft are exploited to validate low-level winds measured by the space-borne Aeolus wind lidar and collect high-resolution wind and turbulence data. Third, different models of momentum transport by shallow convection will be developed to represent its impact on winds. Last, evidence of global relationships between winds and shallow cumulus are traced in Aeolus and additional satellite data and the impact of momentum transport on circulations in a control and warmer climate is tested in a general circulation model. This project exploits my expertise in observing and modeling clouds and convection focused on a hypothesis which, if true, will strongly influence our understanding of the sensitivity of circulations and the sensitivity of climate. It will in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Autonomous optimisation of general conditions for novel reaction' (AOGCNR).

assistant: **Innovation**

This proposal, AOGCNR, proposes to develop a fully autonomous, data-driven methodology for optimising general conditions for a novel organic catalysis reaction. It integrates a self-driving laboratory (SDL) with a Large Language Model (LLM)-enhanced Bayesian Optimisation framework, combining cutting-edge robotics, machine learning and expert chemical reasoning. A two-phase approach is proposed. The first phase uses a statistical pipeline to screen a vast chemical space of over 3 million combinations, reducing it by over 97% to a manageable subspace. The second phase deploys the LLM-enhanced Bayesian Optimisation algorithm within this refined space to autonomously identify general reaction conditions that perform well across multiple substrates. This approach represents a significant advancement over current methods, which typically focus on single-substrate optimisation. The methodology will be validated on both a known reaction and a novel cyclisation discovered by researchers at the University of Liverpool, demonstrating its ability to accelerate the discovery of novel catalytic reactions.This project's impact is significant on multiple levels. It advances chemical research by enabling data-efficient exploration of complex reaction spaces. Societally, it democratises access to advanced chemistry tools. Economically, this approach offers a scalable and cost-effective alternative to traditional trial-and-error methods, streamlining industrial research and development, and contributing to more sustainable and efficient innovation.


**Keywords:** Automation, self-driving laboratory, cheminformatics, Bayesian optimisation, organic catalysis methodology
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Quantify disturbance impacts on feedbacks between Arctic permafrost and global climate' (Q-ARCTIC).

assistant: **Innovation**

Arctic permafrost has been identified as a critical element in the global climate system, since it stores a vast amount of carbon that is at high risk of being released under climate change. The feedbacks between permafrost carbon and climate change are moderated by many factors, including hydrology, topography, and biology. Shifts in these factors lead to highly complex feedbacks between biogeochemical and biogeophysical processes. These are only rudimentarily represented in current Earth System Models (ESMs), in particular due to a scaling gap between processes and model grid.Q-ARCTIC will establish a next generation coupled land-surface model that explicitly resolves highest resolution landscape features and disturbance processes in the Arctic. Model development will be informed by novel remote sensing methodologies linking landscape characteristics and change potential at an exceptional level of detail. Interdisciplinary observations at multiple spatiotemporal scales will deliver novel insight into permafrost carbon cycle processes. All components are essential for our objective to generate an unprecedented process-based hindcast of glacial permafrost carbon state and projection of permafrost sustainability under future scenarios with a focus on abrupt changes.Our ground-breaking research is based on the newly developed ICON-ESM that enables highest-resolution simulations based on high-performance computing infrastructure. The required remote sensing information can for the first time be produced from new pan-Arctic data streams, such as the European Sentinel satellites. Finally, recent breakthroughs in ultraportable instrumentation and mobile air- and water-borne platforms facilitate bridging the gap between in-situ process understanding and landscape-scale surface
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Structural Acoustics of Light Weight Components in the Medium Frequency Range' (1994-1998).

assistant: **Concept**

Interior and exterior noise quality are critical performance characteristics in vehicles. For light weight vehicles, they are even determining, together with crash worthiness, the feasibility of the concept. A proper noise and vibration (NVH) design and refinement approach is hence imperative to allow shorter optimisation cycles at lower cost. In spite of considerable (recent) progress in many fields of NVH engineering, a fundamental design problem still remains with the optimisation of the structural acoustics characteristics of car body panels, especially in the medium frequency range (100 500 Hz) where Finite Element methods lack accuracy and the frequency is still too low to allow the application of Statistical Energy models with sufficient confidence. Therefore, the present project aims at the development of a consistent approach and the required tools to address the problem of medium frequency structural identification and optimisation of car body parts, in specific relation to their structural acoustics behaviour. More specifically the project will focus on the structural coupling between the car frame and the body parts, and the structural acoustics coupling to the car interior. The approach will essentially be based on an experimental methodoloqy for car body modelling (e.g. extending the holographic modal analysis method developed in the EUREKA project HOLO MODAL to real time acquisition of pulsed laser images and for measuring multiple panels inside the car) and for structural coupling (e.g. using test or hybrid data based substructurinq techniques for the panel/frame coupling ). It will be fully integrated with tools for body panel noise ranking and structure borne noise transfer path analysis into a consistent global approach.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Improved chemical analysis and uv spectroscopy using improved deuterium lamps (deuterium lamp standard)', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

A deuterium lamp ultimately controls detectivity in nearly all absorbance spectrometers and detectors especially for the important chromatographic instruments HPLC and CE used in all life areas. This project involves a radical new approach to the D2 lamp design in the form of two variants. The first is a 30W D2 lamp with high stability and brilliance and long lifetime to improve HPLC, CE and conventional UV spectrometer performance. The second variant is a ~250W D2 lamp designed especially for spectroscopy. The 250W lamp allows in a second project part the re-design of a novel spectrometer with high relevance for pharmacy and biotechnology. Both lamp types service instruments that are single beam in character and rely to a great extend on lamp stability in the short & long term. In this sense the new D2 lamp will be an important improved reference standard.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Stable and Chaotic Motions in the Planetary Problem' (StableChaoticPlanetM) targeting Horizon 2020.

assistant: **Abstract**

The planetary problem consists in determining the motions of n  planets, interacting among themselves and with a sun, via gravity only. Its deep comprehension has relevant consequences in Mathematics, Physics, Astronomy and Astrophysics. The problem is by its nature perturbative, being well approximated by the much easier (and in fact exactly solved since the XVII century) problem where each planet interacts only with the sun. However, when the mutual interactions among planets are taken into account, the dynamics of the system is much richer and, up to nowadays, essentially unsolved. Stable and unstable motions coexist as well. In general, perturbation theory allows to describe qualitative aspects of the motion, but it does not apply directly to the problem, because of its deep degeneracies. During my PhD, I obtained important results on the stability of the problem, based on a new symplectic description, that allowed me to write, for the first time, in the framework of close to be integrable systems, the Hamilton equations governing the dynamics of the problem, made free of its integral of motions, and degeneracies related. By such results, I was an invited speaker to the ICM of 2014, in Seoul.The goal of this research is to use such recent tools, develop techniques, ideas and wide collaborations, also by means of the creation of post-doc positions, assistant professorships (non-tenure track), workshops and advanced schools, in order to find results concerning the long-time stability of the problem, as well as unstable or diffusive motions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Coordinating an Observation Network of Networks EnCompassing saTellite and IN-situ to fill the Gaps in European Observations' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

ConnectinGEO’s primary goal is to link existing coordinated Earth Observation networks with science and technology (S&T) communities, the industry sector and the GEOSS and Copernicus stakeholders. The aim is to facilitate a broader and more accessible knowledge base to support the needs of the GEO Societal Benefit Areas (SBAs) and their users. A broad range of subjects from climate, natural resources and raw materials, to the emerging UN Sustainable Development Goals (SDGs) will be addressed. A tangible outcome of the project will be a prioritized list of critical gaps within the European Union in observations and the models that translate observations into practice-relevant knowledge. The prioritized list will include the research activities required to address these gaps. Ultimately, this will increase coherency of European observation networks, increase the use of Earth observations for assessments and forecasts and inform the planning for future observation systems through a sustainable approach that will survive beyond the end of this project.ConnectinGEO has 4 major objectives:a) Enable a European Network of Earth Observation Networks (ENEON) including space-based, airborne and in-situ observations networks. b) Provide a methodology to convert the knowledge needs into a coherent observation and measurement compendium for ENEON strategy and development. c) Apply the ConnectinGEO methodology to identify and assess the priority of gaps. d) Open the results of the project and exploit them beyond the project end.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Structural and functional studies of LARP4, a new RNA binding protein involved in mRNA stabilisation and cell migration', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

RNA-binding proteins (RBPs) act at multiple levels to regulate gene expression, including mRNA splicing, polyadenylation, localisation, stability, decay and translational efficiency and, although central to health and disease, much of this precise concerted regulation remains to be uncovered.  The recently discovered LARP4 is an RBP that affects mRNA stability and binds to polyA as well as the polyA-binding protein (PABP).  Intriguingly, LARP4 has recently been identified as a regulator of cell morphology and migration in an RNAi screen, but little is known about how control of gene expression at the translational level is coordinated during cell migration and invasion. Since aberrant cell migration contributes to the development of human diseases including cancer, chronic inflammation and atherosclerosis, LARP4 represents an excellent RBP to advance our understanding of key cellular mechanisms relating to mRNA processing and turnover. The overall aim of the project is to understand at a molecular level how LARP4 regulates mRNA translation and how this impacts on cell migration, especially in the context of cancer cell biology, using human prostate cancer cell lines as models. For this, a multidisciplinary approach combining biochemistry, biophysics, structural and cell biology will be used.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Greener biological nitrogen removal: minimization of N2O emissions and optimization of the integration issues of the nitritation / Anammox process for main stream wastewater treatment'.

assistant: **Objectives**

Effective treatment of wastewaters is one of the key actions to reduce the nutrient load of surface waters, which is one of the goals in EU policies (Water Framework Directive). There is an urgent need to develop more sustainable wastewater treatment plants (WWTP) to reduce the energy consumption and corresponding carbon dioxide (CO2) emissions. One of the keystones for the development of energy-efficient wastewater treatments is the use of an autotrophic nitrogen removal. Recently, significant emission of nitrous oxide (N2O), a greenhouse gas (GHG) 300 times more potent than carbon dioxide, have been detected associated to the biological nitrogen removal (BNR) in the wastewater treatment. Therefore, the main research objectives of the proposed research project are two: (i) the minimization of N2O emissions during the autotrophic nitrogen removal; and (ii) the achievement of a fully integrated autotrophic nitrogen removal for main stream wastewater treatment. These two aspects will contribute to the development of a truly sustainable WWTP with low carbon footprint. To this end, a mathematical model able to predict the amount of N2O emissions and the performance of a nitritation-Anammox reactor for main stream wastewater treatment will be developed. Validation of the modeling results will be possible through monitoring of the N2O emissions in a pilot plant prototype. Ad hoc process control strategies will be inserted in the model and evaluated through specific simulations. Numerical optimization of setpoints will be carried out to minimize the N2O emissions whereas a high nitrogen removal is achieved. The best process control strategy will be implemented first in a laboratory-scale reactor and later in a pilot scale prototype reactor treating real wastewater to test the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Advanced Hand Sanitizing and Compliance System for the Healthcare Sector' (BioDermaCare) under Horizon 2020.

assistant: **Objectives**

Across the EU four million patients are affected by hospital acquired infections (HAI) every year, causing pain, longer stays in hospital, long-term disabilities and increased resistance to antimicrobials. Around 37,000 people die each year due to a HAIs. The cost is almost €7 billion a year with an average cost of €9,000 per case. Many of these infections, deaths and costs can be reduced by improved hand sanitization.Resani has developed a game-changing Automatic Hand Sanitizer (AHS) solution for improved hand disinfection of healthcare workers including those who suffer from occupationally acquired eczema which often harbours microbial biofilms including Staphylococcus Aureus. Our solution encourages regular use by using a patented eczema- friendly antiseptic which destroys biofilms and reminds staff to sanitize through an app and monitors use through a IoT badging system. The only automated hand sanitizer that guarantees 100% coverage of the hand in 3 seconds without rubbing the hands together or need to dry.The Resani AHS will increase hand sanitizing compliance from 37% to 100% among HCW and will provide hospital administrators with real-time data for statistical analysis, reporting and overall improvement of hand sanitization protocols. We will sell the AHS directly to hospitals and through channel distributors. Resani will also sell the special antiseptic refill cartridges, that are custom made to work with the AHS.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Open and scaleable intelligent metering system for advanced home service ii' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

The objectives are based on the concept of integrated and interactive home systems:- Development, manufacture, and validation of an intelligent process unit (OSIM-AHS), situated at the end users' dwellings, capable of offering energy management services and the communication and interface basic functional blocks for supporting home services.- Development, manufacture, and validation of the Concentrator & Communication Switching device (CCS), situated between the customer premises and the central low voltage unit, capable of communicating with several pieces of OSIM-AHS equipment. The use of this CCS device is enhanced by its alternative two-way data telecommunications system: PLC or telephone.This project, OSIM-AHSII, follows a viability study achieved in EP 9264 OSIM-AHS.OSIM-AHS may be the key to the development of new services, and the aim is to design and realize the building blocks which are needed to establish a communicating architecture between utilities and customer, with a special emphasis on two-way communication with  meters and two-way communication with appliances or systems in homes.The first range of products will be energy management oriented, but other applications will come in a second step when the infrastructure provided by OSIM-AHS Systems is available. In the proposed reference architecture, special attention has been paid to the possibility of upgrading the system services and communications means, without big overcharges or equipment modifications. The existence of a large number of customers having, through this architecture, access to information and services through the HS Power Line Connection, will help considerably in the promotion of the HS products, in countries where the participating utilities operate.