RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Elucidating the Mechanisms of Insect’s Chemical Taste to Understand Specific Host-Plant Selection' (ChemoSense) targeting Horizon 2020.

assistant: **Abstract**

The sense of taste enables an animal to decide what it eats and drinks. Insects are able to discriminate among soluble chemicals via their gustatory receptors (GRs) in order to accept or reject a certain food plant or initiate mating and oviposition. Despite their essential role in the insect’s overall food intake, survival and reproductive success, relatively little is known about insect GRs, especially in beetles. This is surprising given their importance as agricultural and forestry pests, their global distribution and huge species number as herbivorous insects. I aim to identify and characterise GRs that mediate host plant selection in a specialist poplar leaf beetle, Chrysomela populi. These beetles feed on economically important poplar trees and damage timber plantations worldwide. It is hypothesised that the phenolic glucoside salicin in poplar is a major taste stimulant for C. populi and enhances feeding activity. However, it is unknown how salicin or, alternatively, other taste stimulants are detected by, and interact with specific GRs in C. populi to elicit feeding behaviour. I will elucidate these mechanisms by (i) identification of candidate genes encoding GRs in C. populi via tissue specific transcriptome sequencing and transcript visualisation via RNA-FISH, (ii) knock-down of single GR genes via RNAi to test the feeding behaviour of RNAi-silenced beetles, and (iii) test whether any of the taste stimulants from poplar function as in vivo and in vitro ligand for specific C. populi GRs by tissue-specific electrophysiological recordings and heterologous expression, respectively. These results will shed new light on the question how GRs function as regulators for herbivorous beetles to select and consume specific plants, which will significantly advance our kno
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Direct Analysis in Real Time mass spectrometry: meeting the challenges in qualitative and quantitative analysis' (2007-2013) targeting Seventh Framework.

assistant: **Abstract**

Direct Analysis in Real Time mass spectrometry (DART-MS) was reported first in 2005 and gained a wide attention due to the possibility for direct mass spectrometric analysis of solids and liquids, often without any sample preparation and chromatographic separation. According to some opinions, it could be nominated for the next Nobel prize in mass spectrometry. However, until now the general methodology is not yet established and a lot of challenges are to be met before DART-MS will really be considered as a full-scale and powerful analytical method. The available publications contain limited and contradictory data. A lot of capabilities and potentially attractive applications of DART-MS have not been studied or even demonstrated yet.The purpose of the project is the development of the analytical methodology of DART-MS and the establishment of new approaches for analysis of complex samples, based on DART-MS and its hyphenations with different sampling techniques and planar chromatography. It will include detailed studies on optimization of DART instrumental and experimental conditions to provide the best achievable analytical characteristics. The special attention will be given to the coupling of planar chromatography with DART-MS. Possibilities for DART-MS Imaging of small molecule distributions on different surfaces and for analysis of the dried spots of biological liquids on a carrier will be investigated for the first time. Also the following new DART-MS application areas will be studied: fast qualitative and quantitative screening of antibiotics in different food and environmental samples; analysis of bee products (honey, propolis); and identification of aroma compounds and undesired components in foods, drinks and commodities.The implementation of the current proje
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Novel peptide-based therapeutics for reprogramming the tumour stroma extracellular matrix using molecular modelling and computational engineering', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Cancer is the second biggest cause of death worldwide. 90% of cancers are solid tumours, where tumour stromal cells secrete a dense mass of proteins called the extracellular matrix (ECM), part of a protective tumour microenvironment that promotes cancer proliferation, invasiveness, and resistance to chemotherapy and biologics. Several therapies now available or being developed rely on monoclonal antibodies aimed at tumour-expressed antigens, or activation of immune cells. Many such promising immunotherapeutic approaches fail because of this stromal barrier, and/or because of toxicity due to off-target effects. Targeting proteins and pathways in the tumour microenvironment is now considered by oncology experts and pharmaceutical concerns to be critical to the success of beating solid tumours, but no therapies have yet emerged to address this €200+B market. Our platform uses novel molecular computational simulation models to generate small peptides that bind to highly specific sites on ECM proteins and block interactions known to promote tumour aggressiveness. The first of these, TAX2, selectively targets a clinically relevant interaction between the ECM signalling protein Thrombospondin-1 and its receptors, to regulate tumour proliferation, vascularisation, and immune cell (T-cell) infiltration of the tumour. TAX2 shows extremely promising results in 15 preclinical models, including ovarian, pancreatic, colorectal, and melanoma cancers, where it inhibits tumour progression and metastasis. TAX2 also substantially improves the efficacy of antibody therapies when combined in these models. Our current focus is on ovarian cancer, a cancer with high unmet need, and very high mortality rate.  EIC support will enable large-scale manufacture, regulatory steps, and first-in-human,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Characterization of regulatory genomic regions. Development of databases and sequence analysis tools' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

The objectives of the proposed project are to develop and provide tools for the interpretation of genomic DNA sequences with special emphasis on regulatory regions. Sequencing whole genomes will yield a huge amount of data in near future. Systematic functional analysis of these sequences with the standard experimental methods is far beyond existing laboratory research capacities. Thus, we have to rely on in silico approaches at least for planning of targeted experiments. The assessment of the biological meaning of a gene depends not only on methods to predict the structure and function of its gene product, but also on the ability to derive its regulatory expression pattern from the base sequence. Gene control regions pose particular difficulties to in silico function prediction approaches which may partly explain the modes of success of current algorithms addressing this problem. The elementary sequence signals are typically short (in the range of 5 to 30 base pairs) and highly variable, reflecting the biochemistry of the decoding mechanism. As a consequence of these properties, the physiological significance of an individual control module can only be assessed by a comprehensive search involving context analysis within the (putative) regulatory region combined with gene identification methods based on coding region prediction. The technical approaches suggested in this proposal particularly address the recognized difficulties outlined above. Thus, there is an obvious need for programs that enable molecular biologists to efficiently annotate newly unravelled sequence data with tentative functional features. To achieve this, we propose the following programme: 1. Databases that collect experimental relevant data such as TRANSFAC and EPD provide the basis for sequence ana
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'BioXplor’s AI/Cognitive Software Platform accelerates and greatly reduces the cost of discovery research and clinical trials, with a primary focus on rare and inflammatory diseases data.'.

assistant: **Innovation**

BioXplor’s AI/Cognitive Software Platform accelerates and greatly reduces the cost of discovery research and clinical trials, with a primary focus on rare and inflammatory diseases data. The technology has shown a 5-25x reduction in time and 70% cost savings in pilots so far. (TLR stage 6 &7 tests in 5x Biotech and Pharma companies).BioXplor has achieved the Seal of Excellence for our Phase I application in March 2019 (score 13.5) and November 2018 (score 13.09) submissions. Last year, we have been completed acceleration programs at UC Berkeley’s SkyDeck and at Merck, and since then significant progress in building the platform to TLR stage 7 and acquiring new customers and revenue. The platform has been successfully used in tests with 5x Pharma and biotech companies (Merck, Bayer, Novartis, Abcam, EdemedX), and we have 5 new leads, for  our platform for Discovery applications (antibodies, recombinant proteins, biomarker discovery, immunoassays, drug target ID) and Clinical applications (indication expansion, super-responder ID for drug-repositioning, and patient stratification for Biosimilars, all in inflammation projects with Biotech and Pharma).  The current submission is aimed towards bringing BioXplor’s Platform to TLR stage 8, and deploying the our fully tested solution in operational environments at Pharma, Biotech and Academic Research Institutes, for which we are already negotiating pre-orders including 3 year multiyear contracts and 5-10 year partnerships. We have since partnered UC Berkeley, gained access to clinical trials patient data from a major pharma, become a discovery forum member with the 100K Genomes Project, and been selected as a consortium partner for an EU project in the oncology space. We have built a pipeline of EUR750k, with 2019 revenues pro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Hamburg Airport Feasibility Pilot for Seamless Bagshuttle Service' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Bagshuttle (a brand of Shippies GmbH) plans to deliver baggage from airports, trade fairs or railway stations to hotels or any local destination (and vice versa). Our app-based service wants to give travellers baggage freedom so the customer has the freedom to choose public low-emission mobility (e.g. busses, train) or bicycle, e.g. bike-sharing StadtRAD in Hamburg, instead of cars and taxis to reach their destination. Next to that, business travelers can travel to meetings or fares bag free, tourists can enjoy a sight-seeing tour with their luggage being delivered directly to their hotel. Our vision is to establish an international ""Bagshuttle Alliance"" partnering with airlines, airports, railway corps, trade fairs and hotels to provide bag-free travelling. Airlines for example are expecting additional ancillary services to be chosen by more than half of their passengers in the near future. Bagshuttle addresses every traveller: We won´t be another VIP service for a few people and this is why we think we will have a high impact on how we all travel in the future. The service is highly capable of being integrated in existing sales platforms. The multi-billion travel industry is in the process of digital transformation and our app-based service wants to be part of it.  During the program we would start a 4-month pilot at Hamburg Airport for a market survey to get feedback from customers and to find out the logistical challenges. At the end of our feasibility pilot at Hamburg Airport we´ll have a detailed business plan with information regarding market volume, pricing, product characteristics, choice of partners, integrations, market approach and financial planning. Our founder team will make sure that the technical, logistical and financial challenges of this service wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Applying Pilot Models for Safer Aircraft' (A-PIMOD) under Seventh Framework.

assistant: **Objectives**

The A-PiMod proposal addresses improved flight safety by proposing a new approach to human centred cockpit design, which expands the understanding of the human factor in joint human-machine system, taking into account increasing levels of operational complexity and new operational concepts (SESAR). The project will advance concepts for a fully adaptive and human centered automation, through the integration of Pilot behavioural and cognitive models with automation models – resulting in the generation of real time inferences about the Pilot state and mental picture. With this capability it will be able to support, in an adaptive and cooperative way, the total set of functions (both human and automation) necessary to the achievement of a safe flight under a performance driven ATM system (SESAR). In order to do so, the A-PiMod concept depends on an innovative multimodal human-machine interface, which provides a higher level of human-machine interactivity. This advanced interface will be coupled to a dynamic risk assessment evaluation tool, which enables the detection of potential safety gaps due to loss of Situational Awareness for example. This will further enhance the safety improvements of the proposed A-PiMOD human centred automation design, and associated cockpit interface. In addition, the project will advance new training concepts and allied interactive training tools, exploiting real time pilot or crew state inference. This will ensure that pilots become better and faster aware of the new design philosophy and of how to interact with the new systems. In addition to the extensive cockpit based validation exercises, more system based evaluations will be undertaken, to understand the broader safety and operational impact of the A-PiMOD system. Together with the A-PiMod
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'MULTILINGUAL URBAN NETWORK FOR THE INTEGRATION OF CITY PLANNERS AND INVOLVED LOCAL ACTORS' to be submitted under Fourth Framework.

assistant: **Abstract**

MUNICIPIA intends to create an interactive multilingual telematics network for cooperation between European, national and local authorities on urban and regional problems. To this end, it will launch an evaluation programme to determine how such a network might best exploit World Wide Web Internet services. Among additional supporting objectives are the transfer of know-how to ensure the links required and local service availability to maximise their benefits. The project will also boost Internet business activity through publicity for local products and services, electronic advertising and similar activities.The principal objective of the project is to create an interactive telematic value added network, called MUNICIPIA, based on the Internet World Wide Web in a multilingual and user-friendliness context to foster improved dialogue and exchange of experiences between European, National and Local authorities and others local key actors on issues related to solving urban and regional problems through the use of telematic applications. The project aims at establishing the necessary connections to the World-Wide-Web and its associated Internet services (file transfer, multimedia e-mail and information searching) and stimulating in particular the use of these Internet applications among key European urban and regional planning actors. An important second main objective is to identify the conditions for successful exploitation of Internet services in such regions, through a programme of evaluation centred on the experiences and opinions of the Urban and Regional Networks" involving local authorities, and other key actors, already connected with the partners of the project. The project is to engage at least 5-10 cities and/or regions in each of the 3 countries involved.To ac
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Mapping Literary Representations of Coercive Confinement in Ireland, from the Mid-nineteenth Century to the Present' (CONFINED) under Horizon Europe.

assistant: **Objectives**

The main research objective of CONFINED is to define the ways in which literary representations of coercive confinement contribute to Irish national memory. The project focuses on Irish literary representations of coercive confinement from the mid-nineteenth century to the present under the supervision of Prof. Emilie Pine. Its outputs will include a peer-reviewed article in a leading interdisciplinary journal, a digital exhibition on coercive confinement, a podcast on confinement as well as a monograph proposal submitted to a leading university press by the end of the fellowship. These outputs will be enriched by access to unique archival holdings in UCD Library, the National Library of Ireland and RTÉ Archives. I will develop research-specific skills learned via training-through-research in collaboration with experts at UCD; transferable skills developed through hands-on training courses at UCD; and inter-sectoral skills gained through prestigious collaborations with Raidió Teilifís Éireann (RTÉ) and the Museum of Literature Ireland (MoLI). While undertaking a short visit at MoLI, I will host an online conference on Writing Coercive Confinement as well as a workshop with key stakeholders and policy-makers. I will apply for a COST Action Network on Writing Coercive Confinement, strengthening and expanding my networks as well as building towards an ERC Starting Grant application in the immediate aftermath of the fellowship.


**Keywords:** coercive confinement,  cultural memory,  Ireland,  literature,  prison,  asylum,  Magdalene laundry,  industrial school,  borstal,  mother-and-baby home,  Direct Provision,  prose,  theatre,  poetry,  media
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Supporting the smes sUstainaibility and REsilience transition towards industry 5.0 in the mobility, transport & automotive, aerospace and electronics European  ecosystems' (2021-2027).

assistant: **Innovation**

The economic crisis caused by the COVID-19 pandemic and several successive periods of lockdown  demonstrated the fragility of traditional economic sectors, particularly in manufacturing. At the same time, the crisis provided a springboard for the most advanced technology companies, mostly based in the US and China, to open up new markets.The objective of the SURE 5.0 project is to support European SMEs seeking to take advantage of the opportunities brought by the 4th industrial revolution, namely: the digitalisation of production processes and the use of advanced technologies, while fostering the key principles of Industry 5.0: human centricity, sustainability and resilience.  SURE 5.0 covers three strategic ecosystems for the European Union: (i) Mobility, Transport & Automation (ii) Aerospace & Defence, and (iii) Electronics. The project will enable SMEs in these three ecosystems to receive assessments, recommendations, training, tailored services and financial support to implement Industry 5.0 principles that will ultimately provide them a competitive edge.  Selected SMEs will be invited to join the SURE 5.0 Community of Practice Alliance. Led by the members of the consortium, this Community will promote peer-learning exchanges between members and with external organisations leaders.The consortium is composed of 5 clusters (AV, CEAGA, SAC, ANFIA, CORALLIA)  representing more than 1000 SMEs, 3 RTOs (FhG, AIMEN, TALTECH) with an outstanding expertise in supporting companies on technological issues, INIZIATIVA a consulting company specialised in the elaboration of innovative and sustainable business models, F6S a company expert in EU cascade funding projects, and EITM (West) the European Innovation Community in the field of manufacturing. In terms of expected project res