RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Does natural selection align with sexual selection to promote reproductive isolation in different environments? An experimental approach'.

assistant: **Innovation**

Understanding the drivers of reproductive isolation between populations lies at the core of evolutionary biology and is central to understanding how speciation occurs. Natural selection has been traditionally considered a major force driving speciation, but other forces can hamper or reinforce the impact of natural selection on adaptation, including sexual selection. So far, theoretical and empirical studies have produced mixed findings about the extent to which natural and sexual selection act jointly or in opposition to drive reproductive isolation, and hence speciation. Experimental evolution is a powerful tool to test the combined effect of natural and sexual selection to drive population divergence. In this action, I will use seed beetle Acanthoscelides obtectus from long-term experimental evolution lines, which have differed in environmental condition and selective pressures, to explore reproductive isolation as driven by the interaction between local adaptation to a novel environment and sexual selection/conflict. In a novel framework combining phenotypic-level measurements with genomic tools, I will quantify (a) the extent of pre-zygotic reproductive isolation between populations under different environmental regimes; (b) the extent of post-zygotic reproductive isolation, by determining the extent to which hybrid eggs and offspring are of lower fitness than non-hybrids; and (c) gene expression and selection pressures associated with the novel environment at loci associated with natural and sexual selection, which are putative sources of reproductive isolation. This project represents a major advance in our understanding of the role of multiple selective forces in driving species diversity.


**Keywords:** A. obtectus, natural selection, population genomics, repr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'NPlast - A neuroscience school that aims to preserve and restore neuroplasticity in brain disorders' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Brain disorders impose an increasing economical and social burden in the member states of the European Union (EU). For most neurodegenerative diseases and many neuropsychiatric disorders no efficient treatment is available and no cure exists. In the next coming years the number of particularly elderly people suffering from brain disorders will tremendously increase. Predictions from the turn of the century about the exponential increase of dementia patients turned out to be correct and Alzheimer’s disease alone is underway to become the most expensive and most pressing health problem in the EU. The complexity of these diseases requires a more integrative view of the multiple interactions between genes and environment, synaptic processes and neuronal cicuitry. This is, however, not only achieved by training more young scientists in the relevant disciplines. The plastic properties of the brain can only be exploited by scientists that are trained to deal with this complexity and that are familiar with state of the art technology as well as with the principles at different levels of analysis. In consequence it is advisable for a training network to study more than one disease and to train scientists with a wide range of skills and background knowledge. The NPlast consortium consists of four partners from the private and seven partners from the public sector and will provide a research training program for fifteen young scientists. The program covers a broad spectrum of disorders and interventions ranging from synaptopathies and trafficking deficiencies to Alzheimer’s disease, and from altering gene expression programs to manipulations of the extracellular matrix of the brain to preserve or restore synaptic function. The key objective of the NPlast training network is to inv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Reconfigurable smart lens for adaptive imaging'.

assistant: **Innovation**

Adaptive optical elements that enable dynamic control of optical paths are essential components of the last generation of commercial optical devices in a wide range of sectors, including smart phones, microscopy and 3D printing. The main goal of the SMARTLENS project is to exploit a recently developed technology to create a new paradigm in optical imaging by transforming at low cost any conventional static optical lens into an adaptive lens whose imaging properties can be dynamically shaped almost at will. Throughout the project we will advance the maturity of the technology, design and implement a demonstrator as well as establish the exploitation and commercialization strategies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Information Economics With Fundamental Uncertainty: Robustness, Commitment, and Strategic Incentives' to be submitted under Horizon Europe.

assistant: **Abstract**

Many pivotal decisions hinge on navigating fundamental uncertainty, where a comprehensive description of the relevant contingencies and exact odds remains elusive. This project explores how such uncertainty influences learning, innovation, and strategic information sharing. While previous research has made significant strides in exploring information incentives, it predominantly revolves around scenarios with well-defined risks, neglecting the intricate real-world challenges of rapidly evolving, complex environments. My approach leverages decision-theoretic advances to construct novel theoretical frameworks of active learning and strategic disclosure, shedding light on the implications of fundamental uncertainty on the decision-makers' desire for robustness, demand for commitment, and strategic incentives.The project entails the study of active experimentation, modeled as a canonical multi-arm bandit problem, in situations where the experimenter's knowledge about the underlying distribution of payoffs is limited. I propose a new theoretical approach centered on regret minimization and continual re-optimization. This work will generate new insights into the experimenter's dynamic tradeoff between exploitation and exploration in the face of shifting worst-case scenarios, as well as the feasibility of ex-ante optimal experimentation rules.Shifting the focus to strategic interactions, I will investigate how uncertainty over the underlying process of information endowments impacts information-sharing incentives. My work will center on a canonical sender-receiver structure with verifiable information. I will examine the role of the receiver's sophistication in the predictions of such models, in particular, the inevitability of information unraveling. This will challenge some
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Dietary and genetic influences on susceptibility or resistance to weight gain on a high fat diet' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

Diet is a major factor in the development of obesity, but its interaction with susceptible genotype is poorly understood. We will assess the prevalence of high fat consumers (HFC) and phenotype groups that appear to be resistant (DIO-R) or susceptible (DIO-S) to diet induced obesity (DIO). DNA banks from Huffs who are lean or obese and from obese children who consume a HF or LF diet will be screened using candidate genes. A rat model of DIO will be investigated to identify diagnostic biomarkers of DIO-R or DIO-S, and to define the mechanisms involved in defence of obesity. We will also study the influence of foetal and early life nutrition on relevant phenotypes. We will develop a web site to provide accessible information on diet, energetic and genetic predisposition to obesity to a lay audience, in particular obese children and their families.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'A welfare comparison between trade and migration: Local public goods, redistributive policies, and housing markets', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The research project has as general objective to provide further insights to the welfare comparation between trade in goods and migration. A complementary objective is to provide an adequate framework for the discussion of migration policies.There are three issues related to migration flows that are important from a practical point of view and are the object of this research project: The effects of migrants on the cost of providing public goods, the effects of migrants on welfare of local labour force, and the effects of migrants on housing markets. The project aims to build general enough models to analyze the welfare consequences of free mobility of persons within countries when there are public goods that can be congested, to design policies to regulate international migration, and to propose realistic policies to compensate deserving losers from migration flows (some of them based on housing markets).More specifically, the project plans to construct a model with local public goods and congestion levels endogenously determined and, for such a model, define and explore the welfare characteristics of the competitive equilibrium for different forms of financing public goods and find conditions for obtaining gains from migration. On the other hand, the project wants to analyze non linear second best redistributive policies that make Pareto gains from migration attainable. Finally, the project aims to introduce explicitly housing markets in a General Equilibrium model and analyze how housing price equilibrium vary when migration is freed, and how tax policies based on housing market  prices can act a regulatory migration device and as a compensation device of possible losers with migration.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Randomized controlled trial of metformin and dietary restriction to prevent age-related morbid events in people with  metabolic syndrome' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Age–related chronic diseases (ArCD) are complex non-linear processes that depends on a large number of interconnected genetic and metabolic pathways which should be tackled with a many faceted preventive strategy. Calorie-dense diet and sedentary lifestyle are responsible of the growing prevalence of metabolic syndrome (MetS), which, together with tobacco, is the major preventable cause of ArCD, mediated by the increased availability of insulin, growth factors, and inflammatory cytokines. In animals, calorie restriction (CR) is the most potent dietary intervention for preventing ArCD and prolonging life. In humans, we and others have shown that a sustainable CR, resulting in decreased prevalence of MetS, can be obtained through a comprehensive change in dietary habits, reducing animal food and refined carbohydrates, and increasing whole grain cereal products, legumes and vegetables, according to the Mediterranean and macrobiotic diet principles. Metformin (MET), an antidiabetic drug associated with decreased cancer incidence, activates the same gene pathways  activated by CR, including  AMPK/TSC, which reduces energy consuming processes, and cell proliferation  (through the inhibition of mTOR). We propose a placebo controlled randomised trial to test whether treatment with MET, with or without associated CR, reduces the incidence of major chronic diseases, such as cancer, myocardial infarction, stroke, and diabetes. We estimated that randomizing 2,000 women and men aged 55-74 at high risk of developing ArCD because of  MetS, shall provide over 90% power (at alpha = 0.05) to detect a significant 25 to 33% reduction of ArCD incidence in 5 years. In a subsample of the cohort we shall study the genetic and epigenetic mechanisms of the preventive action of metformin and CR.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Highly efficient process for the production of a new environmentally-friendly resin and of innovative composite materials using this resin in high tech and traditional industries.' (AGRO-COMPOSITES) targeting Fifth Framework.

assistant: **Abstract**

The increasing environmental concern of the community lead, during last years, to emergence of needs for new processes that would be agile and eco-efficient. One partner of this project has discover and patented the synthesis of a new environment -friendly resin based on vegetable oils suitable for uses in various application fields ranging from traditional to high tech industry. A consortium was created including several industrials from different areas to develop new processes either using this resin or allowing to produce it. Such processes will be oriented towards modern factory. The optimisation of these processes, that will be done within the present project, will allow to produce some objects based on composite materials in the field of aeronautics, automotive, wood, textile and furniture industry. At end, this project will generate some new environment friendly processes suitable for rapid industrial development and allowing the production of a wide range of product with decreased environmental impact and optimised production costs.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Privacy preserving identity management for digital wallet and secure data sharing and processing for cyber Threat intelligence data' to be submitted under Horizon Europe.

assistant: **Abstract**

PRIVIDEMA represents an industry-driven initiative to advance privacy-preserving technologies in the application areas of cyber threat intelligence, data protection, and identity management. This multifaceted project operates across various research and innovation maturity levels, with the overarching goal of introducing more robust, user-friendly and scalable privacy and security technologies for the European ecosystem. Key components of PRIVIDEMA include: 1. Development of open-source tools, hosting networking events, and initiation of capacity-building efforts to democratize technology access and empower cybersecurity professionals. 2. Advancement of homomorphic encryption capabilities, implementation of hardware acceleration methods, and improvement of Fully Homomorphic Encryption (FHE) usability. 3. Creation and demonstration of a prototype European identity wallet featuring issuer and relaying party functionalities. 4. Development and demonstration of a prototype European privacy-preserving cyber threat data processing system, with real-world testing and validation of innovative technologies. Aligned with the objectives of Horizon Europe, PRIVIDEMA actively contributes to increased cybersecurity, data and network protection, and the establishment of robust digital infrastructures. The project distinguishes itself through its commitment to supporting SMEs as well as promoting open-source development, cross-disciplinary collaboration, and privacy-by-design principles. The solution-oriented approach positions PRIVIDEMA as a pivotal force in advancing cyber-resilient digitalization and the data economy in Europe. PRIVIDEMA's connection to various European strategic initiatives underscores its relevance, with a clear emphasis on real-world applications, innovation beyo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Development of new and cost-effective methods to detect and quantify human pathogenic viruses in water' (MOLVIR), addressing dissemination and exploitation.

assistant: **Impact**

This project aims to develop new and cost-effective methods to detect and quantify human pathogenic viruses in water. European Union MS and Industries are required to assess the microbiological status of water through detection and enumeration of faecal pollution indicator" bacteria. Outbreaks of "new and emerging pathogens" clearly demonstrate that these conventional methods are not sufficient to guarantee the quality of waters and to protect human health. Pathogenic viruses detection relies on cell culture, which is difficult, expensive, time consuming and thus not appropriate for routine monitoring. In addition, most waterborne viruses are impossible to grow.Therefore, there is a need for more efficient methods which are rapid, sensitive, specific and reproducible and that could be developed in commercial products. The project aims to develop molecular methods to detect different enteroviral strains representative of the known human serotypes, including poliovirus and hepatitis A virus. The experiment al approach is quantitative real time Polymerase Chain Reaction (PCR). Appropriate interpretation of a positive-PCR will be an important issue for virus-related health hazard assessment because viral genomes and infectious viruses exhibit different behaviour patterns in water.Seasonal distribution of Enteroviruses in water will be investigated and strains detected in the environment will be compared to human-isolated strains through molecular genotyping. Complementary epidemiological studies may help to det ermine whether human pathogenic strains are water-transmitted. Virulence and infective capacity of isolated strains will be investigated in mice models. This fellowship offers the researcher the opportunity to develop new molecular approaches (Quantitative _PCR) in e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'REseArch, methodoLogIes and technologieS for the effective development of pan-European key GRID infrastructures to support the achievement of a reliable competitive and sustainable electricity supply' in the context of a Seventh Framework call.

assistant: **Objectives**

The European electricity system is facing major challenges to implement a strategy for a reliable, competitive and sustainable electricity supply. The development and the renewal of the transmission infrastructure are central and recognised issues in this strategy. Indeed the transmission system is a complex and strongly interconnected infrastructure that offers a wide range of benefits like reliability improvement, promotion of competitive electricity markets and of economic growth, support for development of new generation and for exploitation of renewable resources. Within this context, the objective of REALISEGRID is to develop a set of criteria, metrics, methods and tools (hereinafter called framework) to assess how the transmission infrastructure should be optimally developed to support the achievement of a reliable, competitive and sustainable electricity supply in the European Union (EU). The project encompasses three main activity-packages: 1) identification of performances and costs of novel technologies aimed at increasing capacity, reliability and flexibility of the transmission infrastructure; 2) definition of long term scenarios for the EU power sector, characterized by different evolutions of demand and supply; 3) implementation of a framework to facilitate harmonisation of pan-European approaches to electricity infrastructure evolution and to evaluate the overall benefits of transmission expansion investments. The expected output of the project is fourfold:   - Implementation of the framework to assess the benefits provided by transmission infrastructure development to the pan-European power system.   - Preparation of a roadmap for the incorporation of new transmission technologies in the electricity networks.    - Analysis of impacts of different scenar