RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'ENABLing cryogEnic Hydrogen based CO2 free air transport (ENABLEH2)'.

assistant: **Concept**

Flightpath 2050 very ambitiously targets 75% CO2 and 90% NOx emissions reductions, relative to year 2000. It is highly unlikely that these targets will be met with carbon containing fuels, despite large research efforts on advanced, and in many cases disruptive, airframe and propulsion technologies, even when coupled with improved asset and life cycle management procedures. Liquid hydrogen (LH2) has long been seen as a technically feasible fuel for a fully sustainable aviation future yet its use is still subject to widespread scepticism. ENABLEH2 will mature critical technologies for LH2 based propulsion to achieve zero mission-level CO2 and ultra-low NOx emissions, with long term safety and sustainability. ENABLEH2 will tackle key challenges i.e. safety, infrastructure development, economic sustainability, community acceptance, and explore key opportunities through improved combustor design and fuel system heat management, to further minimize NOx emissions, improve energy efficiency and reduce the required volumes of LH2. The project will include experimental and analytical work for two key enabling technologies: H2 micromix combustion and fuel system heat management. These technologies will be evaluated and analysed for competing aircraft scenarios; an advanced tube and wing, and a blended wing body / hybrid wing body aircraft, both featuring distributed turbo-electric propulsion systems and boundary layer ingestion. The study will include mission energy efficiency and life cycle CO2 and economic studies of the technologies under various fuel price and emissions taxation scenarios. ENABLEH2 will deliver a comprehensive safety audit characterising and mitigating hazards in order to support integration and acceptance of LH2. Solutions will be proposed for any socioecono
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Performance prediction in advanced pulverised coal-fired utility boilers' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

Objectives The objectives are to improve the environmental effects of firing pulverized coal in atmospheric boilers, and to allow the design of higher efficiency boilers with low emission characteristics. These are to be achieved by fulfilling the following sub-objectives: - To develop improved tools for the prediction and assessment of pulverized coal-fired utility boiler performance, and for the assessment of designs for new boilers in terms of overall operating efficiency, heat transfer and emission performance; - To develop advanced techniques for in-combustion chamber NOx control through the use of pulverized coal as a reburn fuel, and - To improve the capability of predicting the combustion and emission performance of a wider range of coal-based blends. - To provide for techno-economic assessments of different strategies for efficiency improvement and emission reduction. - Ultimately to provide information to give guidelines to policy makers with reference to optimizing the use of the existing stock of European boilers, and further to optimize future developments. Technical Approach The project is managed in three project areas addressing respectively modelling, blends research and coal over coal reburn. A heavy emphasis is being placed on the acquisition of operating data from full scale production plant, backed up by data from pilot scale boiler simulators and laboratory reactors. Extensive model development activities will be undertaken, based on improved phenomenological understanding gained from the experimental research and validated using the pilot and full scale operating data. The ultimate aim is to provide simplified modelling which may be used for rapid assessment of plant operating and design changes. Expected Achievements and Exploitation Expected ach
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Next-Generation Personalized Diagnostic Nanotechnologies for Predicting Response to Cancer Medicine' to be submitted under Horizon 2020.

assistant: **Abstract**

Cancer is the leading cause of death in the Western world and the second cause of death worldwide. Despite advances in medical research, 30% of cancer patients are prescribed a medication the tumor does not respond to, or, alternatively, drugs that induce adverse side effects patients' cannot tolerate.Nanotechnologies are becoming impactful therapeutic tools, granting tissue-targeting and cellular precision that cannot be attained using systems of larger scale.In this proposal, I plan to expand far beyond the state-of-the-art and develop a conceptually new approach in which diagnostic nanoparticles are designed to retrieve drug-sensitivity information from malignant tissue inside the body. The ultimate goal of this program is to be able to predict, ahead of time, which treatment will be best for each cancer patient – an emerging field called personalized medicine. This interdisciplinary research program will expand our understandings and capabilities in nanotechnology, cancer biology and medicine.To achieve this goal, I will engineer novel nanotechnologies that autonomously maneuver, target and diagnose the various cells that compose the tumor microenvironment and its disseminated metastasis. Each nanometric system will contain a miniscule amount of a biologically-active agent, and will serve as a nano lab for testing the activity of the agents inside the tumor cells.To distinguish between system to system, and to grant single-cell sensitivity in vivo, nanoparticles will be barcoded with unique DNA fragments.We will enable nanoparticle' deep tissue penetration into primary tumors and metastatic microenvironments using enzyme-loaded particles, and study how different agents, including small-molecule drugs, proteins and RNA, interact with the malignant and stromal cells t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Trade Law for the Data-Driven Economy' in the context of a Horizon 2020 call.

assistant: **Objectives**

Data has been conceptualized as the ‘new oil’ and although this is a flawed statement, it catches well the value attached to data as a driver of economic growth and innovation, and as a force of change in all facets of societal life. Accordingly, data has emerged as an important topic in contemporary law and policy—on the one hand, because it is critical to understand whether and how different societal areas have been affected by digital transformations, including disruptive phenomena like Big Data and Artificial Intelligence (AI), and on the other hand, because governance toolkits, including legal rules, need to adapt to reflect these implications. Despite the urgency attached to both tasks and the intensified mobilization of policy and research efforts to address them, the topic of data-driven transformation has been explored in a fragmented manner. The domain of trade law has been particularly slow to react—neither do we have a full understanding of the impact of digitization on the entire body of global trade rules, nor have we seen legal adaptation. To put it plainly, despite living in times of industries 4.0, we have trade rules grounded at 1.0.The project addresses these flaws by conducting research in three interrelated fields that seek to: (1) enhance our understanding of the implications of digital disruption for trade law and vice versa, including through a thorough analysis of all existing trade rules that matter for data, as it flows across borders and is regulated domestically; (2) boost our toolkits for tackling the tensions inherent to the data-driven economy by mapping and analyzing all available mechanisms for reconciling economic and non-economic objectives, with a strong focus on data protection but including also other values, such as freedom of spe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Sexual adaptation across evolution: the neural basis of female sexual motivation' to be submitted under Horizon Europe.

assistant: **Abstract**

What are the molecular mechanisms that determine intra- and inter-species behavioral variation? We propose to address this key outstanding question in evolutionary neuroscience by exploring a striking example of adaptive evolution of female sexual behavior. Comparing two closely related nematode species that use different mating strategies, we discovered that while androdioecious (hermaphrodite-male) C. elegans hermaphrodites are indifferent to males, dioecious (female-male) C. afra females exhibit a pronounced sex drive, actively engaging in and initiating mating. Importantly, we found that under induced reproductive pressure, the passive hermaphrodites switch to female-like behavior, suggesting the existence of a suppressed neuronal circuit. In this proposal, we will employ an evolutionary comparative approach to deconstruct the neural basis of female sexual motivation, by addressing three objectives: (1) Explore and quantify the extent and molecular basis of female sexual motivation in C. afra. (2) Characterize the neuronal underpinnings of sexual attraction, by mapping gene expression, connectivity, and network dynamics in females, and (3) Investigate how mating pressure promotes sexual adaptation in C. elegans hermaphrodites, by monitoring the evolving changes in genetics, epigenetics, and the neuromodulatory network in transition states from passive to active sexual behaviors.Our suggested program challenges long-held assumptions about the role of female sexual motivation, which despite its complexity remains understudied compared to male mating behaviors. Our unique approach, utilizing the power of C. elegans alongside tool building for investigating C. afra, will not only unveil the molecular mechanisms governing the emergence of novel female sexual behaviors bu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Precise and reliable autonomous landing for drones, helicopters and other rotorcraft'.

assistant: **Concept**

Landing has always been one of the most dangerous flight phases for any aircraft, but particularly so for rotorcraft (drones, helicopters & other). Challenging weather conditions only increase the likelihood of an accident. 33% of accidents for helicopters take place during approach & landing. 43% of them take place in poor visibility or in bad weather . These accidents lead to injuries of people (both inside the aircraft & on the ground) as well as to hull damage & losses.We have designed & patented the local landing system (LOLAS)—a novel solution that allows safe landing of drones & helicopters in challenging conditions, such as bad weather or a moving platform.We have been successful in beta sales of LOLAS to early adopters in the aerospace & defence industries, generating €280,000+ in revenues. Our current sales pipeline is worth €60,000+. We have major industry players in the EU, US and other countries signed as customers & an extensive pipeline.We have a solution that can be commercialized today with the existing drones & in the mid-to-long term with helicopters. It is future-proof: we are targeting the new market of urban air transportation that is forecasted to reach €4bn by 2022.We are aiming to complete 3 LOLAS product variants by 2021, launch to helicopter market & reach €15m in revenues (75+ FTEs) by 2023.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Hybrid Carbon-free electrically driven fishing longliner with low power methanol combustion engine for propulsion back-up and auxiliary equipment' to be submitted under Horizon 2020.

assistant: **Abstract**

Out of NAVIS high commitment with a greener shipbuilding industry and our many years’ experience in naval architecture and engineering design, we have developed a 100% renewable energy propelled vessel. With the objective of maximizing operational efficiency and green energy whilst improving the handling of the catch, we have taken the current hybrid ship concept to a step further and developed RENShip. Our innovative RENShip is a small fishing long liner vessel powered by a revolutionary hybrid system including a single small combustion engine powered by methanol and a set of lithium batteries, connected to onboard wind turbine and solar panels for supercharging.European fishing fleets are major oil consumers and so, they are greatly responsible for global greenhouse gas emissions from the world’s fleets. Moreover, current ship engines are excessively powerful diesel engines of 50-60% efficiency, resulting in excess of fuel combustion and cost (specially as fossil fuels prices increase over 50%), as well as causing noise and vibration impacting fishing effectiveness and crew’s health. With benefits such as >30% reduction in fuel consumption and associated CO2 emissions and air pollutants (SOx, NOx), considerable reduction in underwater noise, access to fish product’s ecolabels and new tailored displacement hull form, RENship demonstrates its great business opportunity and potential to shift current shipping practices towards efficiency, lower costs and greener operation. Currently located at TRL6, we will integrate all components into a new design to build a pilot ship and validate RENShip in operational conditions, reaching TRL9. RENShip will be the first vessel totally operated by renewable energy and the smallest fishing vessel running with a hybrid propulsion syste
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Representation Theory of Blocks of Group Algebras with Non-abelian Defect Groups' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The proposed project is set in pure mathematics in the areas of representation theory of associative algebras and Lie theory. Its goal is to contribute to the structure theory of the blocks of group algebras of symmetric groups with non-abelian defect groups. The main emphasis of this project will be on the subclass of the RoCK blocks. The main objective of the project is to make a significant contribution towards proving Turner's conjecture about the structure of the RoCK blocks.Recent developments from Lie theory and higher representation theory opened up completely new perspectives. The inspiration for the current proposal comes from the connections of the representation theory of symmetric groups to the representation theory of Kac-Moody algebras.  Our approach to the above families of algebras will involve representation theoretical, combinatorial, homological and computational methods. These methods will represent a combination of classical methods, whose origin is in the work of James, and new methods originating in Kac-Moody algebras and quantum groups. Justification of such a choice of methods lies in the fact that this is one of the ground-breaking approaches that has the potential to produce very important results in a short time span.The proposed project will build on a very recent breakthroughs, it is extremely timely and will be a contribution to central open problems in the field.  Even partial results will have a significant impact in the field and may lead to interesting developments.The subject is one of European excellence and the project will contribute greatly to the preservation of European dominance in the field.This research will be the starting point for a long-term research project and a scientific collaboration between the scientist in charge
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Combinatorial approaches to molecular catalysts' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

Efficient and selective organic molecular catalysts could make important contributions to the future of the European chemical industry; make major contributions in several areas of industrial importance (notably the discovery of pharmaceuticals). The training provided in these facilitating the synthesis of complex molecules with maximum economy and minimal environmental impact. The proposers wish to apply the new techniques will be of great future benefit to the European chemical community techniques of combinatorial chemistry" to the development of such catalysts.They have adopted a generalised design consisting of a scaffold with several attached side-chains, able to act cooperatively on a centrally-located substrate. The scaffold will be immobilised on a polymer support, and the side chains elaborated to yield libraries of structures with potential catalytic properties. Smaller libraries will be tested directly for the desired activity, while larger ones will be "pre-screened" through assessment of binding to transition state analogues. The Network will develop the methodology initially in the context of four sub-programmes, employing complementary technologies and targetted athydrolytic and carbon-carbon bond forming processes. Components for the work will be produced by all eight laboratories and made available throughout the Network."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Clinical portfolio strategy for regenerative muscle stem cell therapies' (MyoPax) targeting Horizon Europe.

assistant: **Abstract**

MyoPax is a women founded company with locations in Germany and in Denmark. Myopax uses a proprietary, patented, first-in-class stem cell technology to become the leading engineering platform for the treatment of skeletal muscle wasting disorders. In Europe alone, more than 20M people are affected by the devastating consequences of muscle wasting. Only palliative care is available.We developed a method to produce pure and highly regenerative muscle stem cell populations (PHSats, Primary Human Satellite cell-derived stem cells). Preclinically, PHSats potently build new muscle and refill the muscle stem cell pool (long-term effect). We are setting up three stem cell platforms for today’s unmet medical needs: 1. Satori: Original PhSats (patented in EU/2021, US/2022) to treat local muscle defects with a single injection. 2. Satgeno: Genetically corrected PHSats in genetic muscular dystrophies. A patent has been filed in 2022. Satori and Satgeno are clinical-trial-ready. First-patient-in is planned for Q3 2023. 3. Satuni: Muscle stem cells derived from induced pluripotent stem cell (iPSC) as a universal allogenic muscle stem cell product. We will deliver preclinical efficacy in 2024 for thus off-the-shelf product.With Women TechEU, we aim to further develop our clinical strategy including an international regulatory and IP strategy, detailed market analysis, and network building with KOL. The mentoring will help us to prepare the fundraising round, which includes company valuation strategies, preparation for due diligence and financial planning. The support will get MyoPax venture capital ready to leverage the technological potential and expand the clinical portfolio- giving back muscle power to those who need it.


**Keywords:** Stem cell therapy, gene therapy, muscle regen