RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Innovative Nanowire DEvicE Design' (INDEED) under Horizon 2020.

assistant: **Objectives**

Nanowires (NWs) exhibit unique properties that make them potential building blocks for a variety of next generation NanoElectronics devices. Recent advances have shown that NWs with predefined properties can be grown, offering a new paradigm enabling functional device prototypes including: biosensors, solar cells, transistors, quantum light sources and lasers. The critical mass of scientific knowledge gained now needs to be translated into NW technologies for industry. FP7-MC NanoEmbrace (ITN) and FUNPROB (IRSES), made substantial contributions to NW research, producing excellent scientific and technological results (>100 journal papers published) and delivered outstanding training in nanoscience and transferable skills to ESRs.Despite demonstrable scientific and technological advantages of NWs, NW-based technology concepts have not yet been translated into market-ready products, because industry and academia have not worked hand-in-hand to commercialize the research findings. Thus, it is essential that NW research is now directed towards customer-oriented scientific R&D; whilst applying innovative industrial design techniques to ensure rapid translation of the basic technologies into commercial devices.This ambitious challenge requires close collaboration between academia and the nascent NW industry, combining the efforts of scientists and engineers to address market needs. Building upon our previous achievements, a team of leading scientific experts from top institutions in Europe, strengthened by experts in innovative design and industrial partners with an excellent track record of converting cutting edge scientific ideas into market products has formed the INDEED network to address this challenge. To enhance employability, INDEED will train young ESRs to become expe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Models of organising access to intensive care for very preterm births : a study of 10 european regional health systems (MOSAIC)'.

assistant: **Innovation**

Access to intensive care for very prefers infants are vital for their survival and future quality of life. These births account for most deaths and cases of severe handicap resulting from the prenatal period. The challenge for health professionals is to provide this 1-1.5% of total births with the best-organised access to specialised care. This project uses the diversity in the organisation of prenatal care in Europe to(1) identify organisational models that promote access to specialised care for pregnant women at risk of very prefer birth and their new-borns;(2) evaluate the impact of these organisational models on the health of very prefer new-borns and(3) determine resource use and user constraints in distinct models. A research consortium will define a common protocol and implement(1) a cohort study of very prefer births and(2) a surveyor health units in 10 health systems with diverse models of organisation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Fcepsilonri-beta gene: identification of regulatory elements and analysis of the effect of genetic variability.'.

assistant: **Objectives**

FcepsilonRI-beta gene confers susceptibility to asthma and allergy. However, it is not known how gene expression is regulated, what are the controlling elements and what the actions of genetic variants in inducing disease. The elucidation of these mechanisms represents the final goal of the project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The role of the raf-1 kinase in cell cycle control and apoptosis in oocytes' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Research objectives and content We will study the role of the raf-1 kinase in oocytes in the mechanisms leading to resumption of the cell cycle, causing entry into metaphase of meiosis-1, and in apoptosis. The raf-1 kinase is a central player in signal transduction in eukaryotic cells although its role in entry into metaphase of the cell cycle in oocytes is highly controversial. Current data suggests that raf-1 may have multiple roles in cell cycle progression. We intend to define precisely whether the requirement for raf-1 is solely to activate the MAP kinase cascade or whether it has an additional role in progesteronemediated meiotic maturation. These experiments will use a combination of expression in vivo of dominant-negative and constitutively active raf-1 mutants and downstream (MAP kinase cascade) protein kinases, followed by measurements of key enzyme activities in vitro. These experiments will be backed up by depletion and reconstitution experiments in extracts in vitro. Secondly we will study the mechanism of apoptosis in oocyte extracts in our working system, which responds to protein kinase signals. We will concentrate on the involvement of the raf-1 kinase, and the potential involvement of downstream peroxidation reactions, in this process. Training content (objective, benefit and expected impact) The objective is to analyse the control of fundamental cellular processes: the cell cycle and apoptosis, in a system amenable to biochemical analysis in vivo and in vitro, by combining different approaches. As a focal point the study uses a well characterized protein, the raf-1 kinase. The use of the oocyte system has been invaluable in cell cycle studies and development of an expertise by the candidate in use of this system is very important. In addition the proj
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'High-fidelity Cardiovascular Modeling from Super-Fast Magnetic Resonance Imaging' (CardioZoom) targeting Horizon 2020.

assistant: **Abstract**

Biophysical computational models of the cardiovascular system need to be adapted to each particular patient from clinical data. The state-of-the-art imaging method for assessing cardiovascular diseases is Magnetic Resonance Imaging (MRI), which is hence the preferred source of data for the personalization of the models. However, MRI is still not able to reliably image the kinematics of thin structures like cardiac valves and the arterial wall. Moreover, MRI measurements of the 3D kinematics of the heart is a challenging task. These restrictions hamper the clinical translation of patient-specific modeling. Therefore, a  new paradigm for model personalization is urgently needed. The ambition of  CardioZoom is to propose novel methods for  biophysical parameter estimation in computational models of the heart, large vessels and valves using MRI data acquired in very short scan times.  The approach will be based on the deep integration imaging and biophysical principles, relaxing the constraints of standard cardiovascular imaging implying long MRI scans. Extensive validations using experimental (phantom) data will be performed and tests on volunteer and patients data are planned. The findings of CardioZoom will allow obtaining clinically feasible, detailed characterizations of the cardiovascular system.


**Keywords:** Cardiovascular computional modeling, inverse problems, medical imaging
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Foresight and Assessment for Environmental Technologies' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

The objective of this proposition is to develop new modelling for assessing policies based on development and dissemination of environmental technologies. A precise assessment of the potential impacts of the introduction of environmental technologies needs two types of expertises:-Knowledge on the characteristics of theses technologies (productivity of factors, emissions, wastes, obstacles and barriers to their adoption).-The use of global quantitative methods i.e. of applied economic models that must take macro-economic feedbacks of policies into account; so the policies may be assessed with economic variables (competitiveness and growth, welfare, etc.),environmental variables (emissions, wastes, environmental welfare, etc.) and social variables (employment, inequalities, etc.).Applied economic modelling is divided into two families, general equilibrium models and macro econometrics ones, these two types of models providing complementary advices: the econometric models are more oriented on the medium term consequences of policies and the general equilibrium on the long term; for these reasons, a complete assessment need the use of the two families. But in the state of the art, these models do not describe precisely enough the mechanisms of environmental technologies adoption. So, in order to achieve the objective of the project, we propose to modify the mechanism of two models, the econometric model NEMESIS and the two general equilibrium models GEM-E3 (EU-25 and World) for assessing policies that modify directly or indirectly the adoption of environmental technologies. The modification will be grounded on a deep knowledge of environmental technologies and will involve a new decision module for technology adoption. Three types of policies will be assessed with the new
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Transparent Solar Panel Technology for Energy Autonomous Greenhouses and Glass Buildings'.

assistant: **Objectives**

According to United Nations estimations, the world population will reach to 9,7 billion by 2050.  Food, energy and water are the three critical resources that must be managed if mankind is going to thrive. With these figures, we will need a 70-100% increase of food supply to maintain the current nutrition levels. Greenhouse farming is a solution to the food worldwide demands as it can increase the food production per acre up to 100% compared to open field agriculture. Although the energy consumption by agriculture made up only 2.8 % of final energy consumption in the EU-281, the global leader in greenhouse production of horticultural products, The Netherlands, has the highest energy consumption in Europe (7.2 %), clearly showing the impact of Greenhouse farming on energy sources. On top of that, the world to which we are currently heading also deserves energetic sustainable solutions to satisfy the growing rate of electrification in the extended populated areas. The global primary energy demand could increase by 50% by the middle of the century. Nowadays, buildings account for nearly 40% of the total energy consumption globally but it is estimated that potential energy savings in buildings could reach between 20% and 40% with new solutions. Solar panels enable energy savings; typically installed on the roof, they do not offer versatility for other type of application, such as windows to allow the entrance of the light inside buildings or greenhouses.Our solution, PanePowerSW is the unique transparent (up to 70%) solar panel glass that generates clean energy through PV technology and more importantly allows the light to shine through greenhouses and commercial buildings windows. Completely aligned with the EU 2020 Energy Strategy, PanePowerSW not only contributes to the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'SKilled, Innovative & Entrepreneurial Scientists' (SKIES), addressing dissemination and exploitation.

assistant: **Impact**

Through the SKIES project, the consortium partners will provide PhD and 1st year postdoctoral researchers in the field of astronomy with a new set of skills integrating open science, innovation and entrepreneurship, thereby equipping them for a career that allows them to fulfill their potential and contribute to society and economy. A Train the Trainer programme builds the capacity of the teaching staff, so that they have the training and tools to continue the programme beyond the life of the project. Online training will be made available to support the partner as well as other organisations interested to run similar courses.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Robotic Dynamic Manipulation' (RODYMAN).

assistant: **Concept**

The goal of the RoDyMan project is the derivation of a unified framework for dynamic manipulation where the mobile nature of the robotic system and the manipulation of non-prehensile non-rigid or deformable objects will explicitly be taken into account. Novel techniques for 3D object perception, dynamic manipulation control and reactive planning will be proposed. An innovative mobile platform with a torso, two lightweight arms and multifingered hands, and a sensorized head will be developed for effective execution of complex manipulation tasks, also in the presence of humans. Dynamic manipulation will be tested on an advanced demonstrator which is currently unfeasible with the prototypes available in the labs, where the application scenario is conceived to emulate the human ability to carry out a challenging robotic task. The research results to be achieved in RoDyMan will contribute to paving the way towards enhancing autonomy and operational capabilities of service robots, with the ambitious goal of bridging the gap between robotic and human task execution capability.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Connections between algorithmic and geometric properties of groups'.

assistant: **Concept**

The topic of this project is the study of groups from a variety of perspectives: algorithmic, combinatorial, geometric and algebraic. The common thread of this work will be solving equations in groups, and understanding what kind of role the nature of the solutions obtained plays in determining the properties of the groups. We will solve problems in areas that range from fixed point theory in free groups and the Post Correspondence Problem in free groups, to properties of a large class of relatively hyperbolic groups. The topic we suggest and the specific questions are of interest to both mathematicians in group theory, geometry and logic, and to computer scientists. Thus the work we propose will bring many different communities together, and will employ techniques from diverse fields.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Augmented lagrange-sqp methods for the control of fluid flow' (1994-1998).

assistant: **Innovation**

Research objectives and content The research objective is the development of efficient numerical methods for the computation of optimal and suboptimal controls for fluid flows and the theoretical justification of the methods. On the way towards this aim the most sophisticated methods from numerical fluid mechanics and numerical optimisation must be combined. The augmented Lagrange-SQP method as solver for the optimal control problem Involving the instationary Navier-Stokes equations as state constraints will be combined with state-of-the-art methods for the numerical solution of laminar flow problems, such as operator-splitting methods. This approach joins a second order numerical optimisation scheme with highly accurate time integration. Therefore it will provide a significant advance compared with only linear convergent gradient-type methods that are usually applied to the numerical solution of control problems in fluid flow. A similar idea will be used for the numerical treatment of suboptimal control strategies such as reduced order modelling and instantaneous optimisation. Application of augmented Lagrange-SQP methods to the solution of the control problems arising i this approaches will significantly speed up their numerical solution. Training content (objective, benefit and expected impact) The objective here is to gain expertise in the rapidly developing area of efficient numerical optimisation methods for large-sca problems and to bring in experience in modelling and the numerical solution of optimal and suboptimal control problems for laminar flows. The benefit clearly is in settling joint work with the members of the U-Graz group, especially with the participants of the 'Spezialforschungsbereich Optimierung und Kontrolle' in a very well developed research atm
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Novel viral therapy through targeting DNA repair' (NOVITREP), addressing dissemination and exploitation.

assistant: **Impact**

Natural epidemics and outbreaks of emerging infectious diseases are a growing problem internationally. RNA viruses remain under constant attention due to the recent Zika virus (ZIKV) outbreak with potential causal relationship with microcephaly of newly born babies and Ebola virus (EBOV) and Crimean-Congo hemorrhagic fever virus (CCHFV) causing life threatening hemorrhagic fever, demonstrating how zoonotic viruses pose a major global health concern. There is an ongoing need to discover novel therapies to battle these pathogenic viruses given that no specific therapy exists. Developing new antiviral treatments by targeting host cell proteins needed in the viral life cycle is an emerging strategy to improve therapeutic power and reduce acquired drug resistance. Based on the results from the ERC grant Genetic Networks as a tool for anti-Cancer Drug Development (GENECADD), we have developed potent inhibitors to DNA repair proteins that disturbs repair of oxidative DNA lesions. To our surprise, we observed, in collaboration with Public Health Agency of Sweden, that these inhibitors potently prevent ZIKV, EBOV and CCHFV viral replication in human cells, suggesting that these inhibitors may be used as antiviral therapeutics. Further investigation into the possible mechanism of action revealed that our inhibitors prevented the repair of oxidative damage to RNA. Here, the overall aim is to (1) further develop and optimize our inhibitors as a novel antiviral target and demonstrate proof of concept, (2) explore and secure IP (3) develop a business plan and (4) perform a market analysis. The overall goal is to develop general antiviral treatments made available to virus-infected individuals through a public foundation in low-income areas or through a company in the Western world.