RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'COMPUTER-AIDED EFFECTIVE FRACTURE RISK STRATIFICATION OF PATIENTS WITH VERTEBRAL METASTASES FOR PERSONALISED TREATMENT THROUGH ROBUST COMPUTATIONAL MODELS VALIDATED IN CLINICAL SETTINGS' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Cancer patients (2.7M in Europe) with a positive prognosis are exposed to a high incidence of secondary tumours (≈1M). Bone metastases spread to the spine in 30-70% cases, reducing the load bearing capacity of the vertebrae and  triggering fracture in 30% cases. Clinicians have only two options: either operate to stabilise the spine, or leave the patient exposed to a high fracture risk. The decision is highly subjective and can either lead to unnecessary surgery, or a fracture significantly affecting the quality of life and cancer treatment.The standard-of-care to classify patients with vertebral metastasis are scoring systems based on radiographic images, with little consideration of the local biomechanics.  Current scoring systems are unable to establish an indication for surgery in around 60% of cases.  Thus, there is an unmet need to accurately and timely quantify the risk of fracture to improve patient stratification and identify the best personalised treatment.This interdisciplinary project will develop Artificial Intelligence (AI)- and Physiology-based (VPH) biomechanical computational models to stratify patients with spine metastasis who are at high risk of fracture and to identify the best personalised surgical treatment. After rigorous model training with clinical (2000 retrospective cases) and biomechanical (120 ex vivo specimens) data, the new approach will be tested  in a multicentric prospective observational study (200 patients). The models will be combined in a decision support system (DSS) enabling clinicians to successfully stratify metastatic patients. The models and the DSS will be designed so as to be suitable for regulatory requirements and future exploitation.METASTRA will propose new guidelines for the stratification and management of metastatic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Intelligent additive manufacturing of SMART low-carbon cementitious composites' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

To tackle the challenges of climate change, there is a growing emphasis on developing green, eco-friendly resources alongside advanced digital technologies. The construction industry is undergoing significant transformations in both materials and digitalisation. With the European Union facing resource constraints, there is a pressing need for innovative solutions to replace CO2-intensive materials and conserve natural resources. In response, the construction sector is increasingly adopting sustainable practices and materials, particularly in concrete technology. These efforts aim to reduce the environmental impact of concrete production, extend structural lifespans, minimise resource consumption, and improve the reliability of new construction technologies.The I am SMART project seeks to address these challenges by promoting a fully automated, greener, circular economic model for production and consumption. The project specifically focuses on developing a novel, intelligent 3D printing technology, supported by artificial intelligence (AI), capable of producing highly accurate printed structures. Additionally, the project aims to develop environmentally friendly cementitious feedstock derived from construction and demolition waste (CDW), as well as low-grade clay minerals, suitable for use in load-bearing building blocks. The project intends to imbue the structures with smart properties by integrating graphene-based materials (GBMs) into the feedstock, significantly enhancing their service life and reducing maintenance costs.The expertise of the Fellow, Dr. Mehdi Chougan, and the supervisor, Prof. Pawel Sikora, is complementary and will facilitate the development of novel construction materials and technologies through a reciprocal knowledge transfer and comprehensive tr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Optimization and application of Intense High-Order harmonics' in the context of a Seventh Framework call.

assistant: **Objectives**

High-order harmonic generation (HHG) as a relatively inexpensive and widely available alternative source in the x-ray region was discovered nearly 20 years ago. The physics is now well understood. Applications are emerging, e.g. in attosecond science. The main difficulty, however, remains the low conversion efficiency and the low number of photons available. Efforts must be undertaken to further increase the output energy of high-order harmonic. The main objective of this proposal is to optimize high order harmonic generation and to explore some of its applications. Single atom response and collective effects will be both considered for the optimization of high-order harmonic generation. The mixing of the fundamental laser with double frequencies and even with an attosecond pulse train will be used to enhance the single atom efficiency. The collective emission will be optimized by increasing the total radiation volume and by achieving phase-matching conditions in different spectral range, developing in particular, quasi-phase matching techniques with weak counter propagating beams. Three applications of intense high-order harmonics will be explored, time-resolved digital in-line holography, nonlinear optics in the extreme ultraviolet range and seeding for free-electron laser research.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Genomic Regulatory Systems of Human X-linked neurological diseases' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

NeuroXsys will generate regulatory maps and models of the human X chromosome based on evolutionary conservation, with special attention to genes and regions implicated in X-linked neurological diseases. Vertebrate chromosomes are subdivided into domains of genomic regulatory blocks (GRBs) and NeuroXsys aims to map all GRBs on the X chromosome through bioinformatic approaches, extract gene regulatory sequences, and model their activity through transgenic reporter assays in the zebrafish juvenile and adult brain. One of the major deliverables of this project will be the publication of an online database that achieves correlation of disease genes ordered with respect to their regulatory regions and their experimentally and bioinformatically assessed function. NeuroXsys will seek to identify human disease mutations in neural gene regulatory elements. Implicated elements will be studied as regulators at single cell resolution in the zebrafish and mouse brain, defining expression patterns driven by the normal and mutant human regulatory DNA sequences. NeuroXsys will generate a regulatory map of a human chromosome.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Facilitating innovation in renewable energies'.

assistant: **Concept**

The overall strategic aim of this proposal, in keeping with the EU policy, which attaches significant importance to the participation of SMEs in EU R&D projects, is to facilitate and foster the participation of SMEs from the Renewable Energy sector (RES) in the framework programme, with a clear focus on the upcoming FP7.The strategic approach will be based on: - the identification of innovation potential in SMEs - a bottom-up" approach in mobilising SME participation - the creation of Interactive European sectoral workshops - a complete guidance and follow-up programme to ensure that SMEs are provided with the proper continuous support and guidance from a panel of experts.To this end the following operational objectives and goals will be met: - Identification and targeting of SMEs to participate in FIRE. - Preparation of Innovation Audits - Organisation of European Sectoral Workshops. - Promote SME participation in existing and future RTD. - SME Clustering."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'The Colonized Cannot Consent: A Decolonial Analysis of Data Rights, Data Sovereignty, and the Doctrines Underpinning Large-Scale AI Systems', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Situated at the intersection of colonial history and sociotechnical analyses of AI, COLONAILISM investigates the apparent degradation of the doctrine of (digital) consent, specifically as it pertains to data collection by AI labs for the development of large-scale AI systems. Its analysis excavates the strong and instructive analogy with the period in colonial history during which the very same concept was subject to scrutiny because critics came to argue that Indigenous actors lacked the capacity to give verifiable consent in treaties involving the cession of sovereign rights. Such a revision resulted in conditions that caused 75% of the world's people to become subject to colonial powers. The analogy suggests the same power concentration/alienation has the potential to recur (if it hasn’t already) following rather similar dynamics in the scramble for user data that is accompanying the development of new foundation models. Importantly, COLONAILISM makes interventions not only in the academic discourse, but also in policy formation (at the municipal and global levels), and industry by developing new decolonial ethics, safety, and governance toolkits AI labs can use to identify and mitigate practices that are harmful to human systems or exploit their value unfairly.


**Keywords:** Artificial Intelligence,  Digital Inequality,  Digital Colonialism,  Internet Geography,  Data Ethics and Governance,  AI Ethics and Society,  Data Collection Practices,  Data Sovereignty
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how '“BDVB Oil Stick” – Key enabling technology for online monitoring of crucial electric grid infrastructure. Striving for global market leadership' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The R&D Team of Passerro GmbH has developed the BDVB – Break Down Voltage - Basic Oil Stick. The BDVB Oil Stick, enables for the first-time online measurements of transformer oil dielectric breakdown strength. Using multi-frequency ultrasound spectroscopy, the Oil Stick determines simultaneously break down voltage (BDV), temperature (T) and oil humidity (Wc). Transformers are crucial infrastructure assets of Europe’s and the world’s power grids, which must be controlled and governed carefully. Today’s power supply with huge but fluctuant shares of renewable energy (solar, wind) seriously stresses transformers– leading to an increased degeneration of the transformer insulating oil and thus to a significant influence of performance and decrease of their life time. If the oil’s insulating capacity is down, transformers can’t resist higher voltages as well as the power load and often break down in fire after short circuit. A transformer loss results most often in tremendous damages: loss of production capacity, loss of power supply, loss of grid stability and supply security. The replacement time of power transformers lasts up to 80 weeks and is cost intensive. To date, no reliable online monitoring of the crucial oil parameters is available, and the transformers are operated merely in a manner of blind flying.Passerro developed the BDVB Oil Stick to TRL 6-7. Functionality has been successfully demonstrated, during long-time operation in transformers in Italy, Romania and Germany. The next step is the consequent commercialization and distribution of the device by efficient marketing and business development.   The BDVB Oil Stick enables a groundbreaking transformer asset management system and allows the accurate utilization of the grid capacities. Moreover, it is a key enab
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Identification and characterisation of a redox sensor controlling swimming behaviour in rhodobacter sphaeroides' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Research objectives and content Rhodobacter sphaeroides is a motile, facultative phototrophic bacterium able to sense and respond to several stimuli (light, oxygen, nutrients, repellents). This is the first species in which multiple chemosensory pathways, responsible of a balanced response to an ever-changing environment, have been identified. The main research objectives are: to identify the receptor sensing changes in the rate of electron transport induced by light, oxygen and naerobic electron acceptor, compare this to other redox sensor and analyse the interactions with the electron transport chain; to establish which of the cytoplasmic chemosensory pathways is involved; how these different signals are integrated; to investigate how the swimming behaviour is modified by this sensory signal. The project will involve molecular biology techniques (gene cloning and sequencing, PCR amplification, mutagenesis, analysis and control of gene expression); protein chemistry; redox spectroscopy;kinetic measurements; computerised motion analysis. Training content (objective, benefit and expected impact) This project will allow me to learn a full range of molecular techniques and provide the unique opportunity to integrate these with biophysical analysis and computer modelling. It will be the first description of integration of redox sensing and chemosensing in a non-enteric species and allow modelling of the effects of different, conflicting gradients on the behaviour of bacterial populations in the environment. Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Optimizing a deployable high efficacy malaria vaccine' (OptiMalVax) targeting Horizon 2020.

assistant: **Abstract**

A highly effective malaria vaccine against Plasmodium falciparum should help prevent half a million deaths from malaria each year.  New vaccine technologies and antigen discovery approaches now make accelerated design and development of a highly effective multi-antigen multi-stage subunit vaccine feasible.  Leading malariologists, vaccine researchers and product developers will here collaborate in an exciting programme of antigen discovery science linked to rapid clinical development of new vaccine candidates. Our approach tackles the toughest problems in malaria vaccine design: choice of the best antigens, attaining high immunogenicity, avoiding polymorphic antigens and increasing the durability of vaccine immunogenicity and efficacy.We take advantage of several recent advances in vaccinology and adopt some very new technologies:  sequencing malaria peptides eluted from the HLA molecules, parasites expressing multiple transgenes, multi-antigen virus-like particles constructed with new bonding technologies, delayed release microcapsules, and liver-targeted immunisation with vaccine vectors.We enhance our chances of success by using a multi-stage multi-antigen approach, by optimising the magnitude and durability of well-characterised immune responses to key antigens, and using stringent infectious challenges and functional assays as established criteria for progression at each stage.The consortium comprises many of the foremost researchers in this field in Europe with leading groups in the USA, Australia and Africa. We link to EDCTP programmes and harmonise our timeline to fit with the recent roadmaps for malaria vaccine development.  We include a major pharma partner and several excellent European biotech companies helping enhance Europe’s leading position in the commer
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Continuous-flow Photoelectrochemical Cells for Carbon Dioxide Valorization' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

Technologies utilizing carbon-dioxide (CO2) as a feedstock to generate valuable products will play a key role in turning the chemical industry onto a more sustainable path. This project addresses the efficient utilization of solar energy and CO2 by introducing a novel technology to produces base chemicals and fuels from non-fossil fuel resources, using an original device architectures for the direct photoelectrochemical (PEC) conversion of CO2 and H2O. During my ERC Starting Grant project we have identified 4 different approaches for PEC CO2 reduction: (i) direct PEC reduction (photocathode), (ii) direct PEC oxidation (photoanode), (iii) PEC reduction and oxidation (photocathode+photoanode tandem), (iv) buried light absorber + EC. In all cases we focus on membrane separated, zero-gap cells, where humidified CO2 can be used as input. This approach will open the opportunity to use industrial exhaust fume (rich in both CO2 and H2O) directly as feedstock for the generation of valuable chemicals. There are four main objectives of this project, which together ultimately result in a preliminary business plan and a roadmap to move PEC_flow cells to commercialization. These are to (i) Validate laboratory results from the ERC HybridSolarFuels Starting Grant, obtain operational parameters under realistic conditions, which can be used in modelling. (ii) Perform technoeconomic and life cycle analysis to select the optimal PEC cell configuration for future activities. (iii) Clarify IPR position and carry out market analysis (including stakeholder- and competitor analysis). (iv) Based on all the above, develop a business plan, which paves the road for future activities, ultimately leading to commercialization.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Easy Reading: A Framework for Personalised Cognitive Accessibility when using Original Digital Content' (2014-2020).

assistant: **Concept**

The “Easy Reading” framework will improve the cognitive accessibility of original digital documents by providing real time personalisation through annotation (using e.g. symbol, pictures, videos), adaptation (using e.g. layout, structure) and translation (using e.g Easy-to-Read, Plain Language, symbol writing systems). The framework provides these (semi-)automated services using HCI techniques (e.g. pop-ups/ Text-To-Speech (TTS)/captions through mouse-over or eye-tracking) allowing the user to remain and work within the original digital document. This fosters independent access and keeps the user in the inclusive discourse about the original content. Services adapt to each user through a personal profile (sensor based tracking and reasoning of e.g. the level of performance, understanding, preferences, mood, attention, context and the individual learning curve). The interdisciplinary project team includes users with cognitive disabilities in all phases through the Inclusive Participatory Action Research Method (IPAR) ensuring to address real users´ needs.The “Easy Reading” framework is planned as a cloud based, open source and freely available support infrastructure. It will reach as many people with limited reading and language skills (e.g. people with cognitive disabilities - ~2,5% of the population - older adults, people with a different mother tongue) summing up to 25% in some regions or countries. Additionally, many more people will enjoy exploring new and unfamiliar content using personalised access. This framework integrates and supports state-of-the-art and future R&D. It incorporates tools for annotation, adaptation and translation of content by providing a sustainable user-centred eco-system for personalisation. It promotes European ideals and enables independe