RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Development of a model of in vitro endochondral ossification with neovascularisation' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The aim of this proposal is to develop an in vitro model of endochondral ossification combined with neovascularisation in order to develop treatments for musculoskeletal ailments and to enable us to better understand the processes leading to tissue formation and disease processes, such as osteoarthritis. The process of endochondral ossification is that by which bone is formed not directly but by first developing cartilage, which is subsequently mineralised and vascularised. These two processes are intimately linked. This project will use adult human marrow stromal cells to induce bone formation via chondrogenesis and chondrocyte hypertrophy as occurs with endochondral ossification. Neovascularisation will also be induced separately using the same cell and scaffold source. These constructs will then be combined in a truly novel approach to understand the role of vessel invasion in bone and cartilage formation. Generation of a viable vascularised bone construct will also take place. In the coming years, with an increasing demographic trend towards an older population in Europe and worldwide, there is a serious socioeconomic need for the development of new treatments for musculoskeletal ailments. One of the problems with current tissue engineering approaches to these problems is a lack of basic understanding of the complex process underway in tissue repair in vivo. This model will serve two purposes. Firstly it will deepen this understanding and secondly, it will offer several potentially suitable treatment options for bone and cartilage repair.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Local Structure of Sets, Measures and Currents', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The objective of this research proposal is to develop new methods to answer a number of fundamental questions generated by the recent development of modern analysis. The questions we are interested in are specifically related to the study of local structure of sets and functions in the classical Euclidean setting, in infinite dimensional Banach spaces and in the modern setting of analysis on metric spaces. The main areas of study will be:(a) Structure of null sets and representation of (singular) measures, one of the key motivations being the differentiability of Lipschitz functions in finite dimensional spaces.(b) Nonlinear geometric functional analysis, with particular attention to the differentiability of Lipschitz functions in infinite dimensional Hilbert spaces and Banach spaces with separable dual.(c) Foundations of analysis on metric spaces, the key problems here being representation results for Lipschitz differentiability spaces and spaces satisfying the Poincar\'e inequality.(d) Uniqueness of tangent structure in various settings, where the ultimate goal is to contribute to the fundamental problem whether minimal surfaces (in their geometric measure theoretic model as area minimizing integral currents) have a unique behaviour close to any point.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Design and synthesis of bulk-active polymeric organic electrocatalysts for efficient electroorganic synthesis'.

assistant: **Innovation**

As the top industrial energy consumer, the chemical industry must rapidly develop new low-carbon technologies to lower the industrys carbon footprint for preparing chemicals and materials for our everyday life. Current synthetic approaches have a low atom economy and rely on the functionalization of reagents with reactive groups that form desired products at elevated temperatures or pressures. These processes are wasteful and energy-intensive, they form hazardous side products and require energy for heating that is often provided by fossil fuels.Imagine a future where organic chemical reactions are driven with electricity from renewables with a high atom economy and fewer side products. Electroorganic synthesis holds great promise for achieving these goals since reactive intermediates are formed in situ at electrode surfaces, forming products with high selectivities under efficient reaction conditions. While the field is rapidly maturing and highly selective processes are reported for a wide spectrum of reactions, the majority of electrode materials currently employed are based on precious metals. Relying on precious metals for developing the technology is a risk due to their scarcity, supply-chain bottlenecks, and high cost. PolyElectroCAT develops a new class of electrode materials for efficient electroorganic synthesis using solely earth-abundant elements. The materials are redox-active carbon-based materials with tailor-made metal complexes that create high activity and selectivity for energy-uphill, reductive electrocatalytic reactions. These materials achieve functionality rarely achieved for metals where electrode materials are solution processible and function as binder- and additive-free electrodes. Moreover, the electrode reacts volumetrically, enabling the ex
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Integration of researchers from the accession states into fp5' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

The applicants propose to carry out a series of events aiming to increase the successful participation of researchers from Bulgaria, Czech Rep., Cyprus, Hungary, Romania, Slovakia and Slovenia in FP5 proposals. The project will contain a study on the specific needs of proposers from Accession States and on their integration into European networks followed by a workshop where results will be discussed. A study on Improvement and resubmission of rejected proposals - learning from Consensus Reports" will be followed by a workshop and a series of four seminars for Naps and successful project partners from the participating countries. These seminars will focus on questions of management and administration of EU projects. In addition to these three work packages the partners in this project - all of who are coordinating National Contact points (Naps) - will create an informal cooperation network for the exchange of experience."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Next Generation GEOSS for Innovation  Business' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The NextGEOSS project will implement a federated data hub for access and exploitation of Earth Observation data, including user-friendly tools for data mining, discovery, access and exploitation. This data hub will be supported by a strong commitment to the engagement of Earth Observation and related communities, with the view of supporting the creation of innovative and business oriented applications. The main general objectives for NextGEOSS are to 1) Deliver the next generation data hub and Earth Observation exploitation for innovation and business; 2) Engage communities, promoting innovative GEOSS powered applications from Europe; and 3) Advocate GEOSS as a sustainable European approach for Earth Observation data distribution and exploitation. NextGEOSS engages main providers of Earth Observation data, including Copernicus Collaborative Ground Segments and Core Services. While continuing to support the GEO-DAB and OpenSearch as the middleware components in charge of interconnecting the heterogeneous and distributed capacities contributing to GEOSS, NextGEOSS focuses on a fundamental change to facilitate the connectivity to the European and global data centres with new discovery and processing methods. It will leverage Web and Cloud technologies, offering seamless and user-friendly access to all the relevant data repositories, as well as providing efficient operations for search, retrieval, processing/re-processing, visualization, analysis and combination of products from federated sources. NextGEOSS includes a set of demonstrative pilot activities, which will showcase the system’s capabilities, and a number of initiatives devoted to engagement of GEO and other EO-related communities.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Orthopaedic shoes operation changed from a small shop operation to a large scale production system with a new arrangement (BONUS-ORTHO)', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

Our new technology and method will change the traditional orthopaedic shoes operation from a small workshop operation to a more efficient large scale production system, i.e. with a new technical arrangement. The new technique consists of a proposed new standardised fitting system, a new ordering system by Internet, new production machines and factory layout. This will make the distance between producers and orthopaedic workshops less important or not of any importance at all. With the bonus ortho" system the producer of the orthopaedic shoes can be anywhere and the standard orthopaedic workshop becomes more a fitting and service shop. The system will also help workshops to get more opportunity to get bigger customer groups."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Bridge Management in Europe'.

assistant: **Concept**

To develop modules for an outline framework for a bridge management system. To achieve this a number of particular objectives have been identified, each of which addresses one of the modules required for a bridge management system. These are as follows:- to develop methods and produce guidelines for the numerical evaluation of defects in concrete structures and to develop research software for the categorisation of deteriorated concrete members using neural networks; - to derive general guidelines based on current knowledge for the assessment of the load carrying capacity of bridges; - to produce recommendations for the modelling of deterioration in the assessment of bridge carrying capacity;- to consolidate and improve existing knowledge on the modelling and monitoring of chloride penetration in concrete; - to develop the basis for a decision making system on whether to repair, strengthen or replace a bridge; - to develop the methods and provide guidelines for prioritisation of maintenance options.The final objective will be to examine how the various modules could be drawn together to form an outline framework for a bridge management system. %To-date eight bridges on the Norwegian coast north of Bergen have been selected for trials. Further demonstration sites and case studies will be selected. %The following projects have been noted as undertaking work that is relevant to BRIME: BRITE/EURAM P3091. This is concerned with the development of a system (IQOA) for determining the condition of a bridge. RIMES - An OECD project to develop a Road Management System including bridges. WAVE (Weighing-in-Motion of Axles and Vehicles for Europe) DIVINE (Dynamic Interaction of Vehicles and Infrastructure Experiment).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Novel Ti Alloy- Hydroxyapatite Nanocomposites via Ultrasonic Powder Consolidation' under Seventh Framework.

assistant: **Concept**

New implant-materials are increasingly being sought to augment the developments in orthopedics and dentistry. Implants, made of composite materials that rely on osteoconduction for fixation, are increasingly replacing traditional cemented prosthesis.  It is well known that metals and alloys exhibit good mechanical properties. However, their use is confronted with biocompatibility issues. Hydroxyapatite (HA, Ca10(PO4)6(OH)2), a compound that shows a very similar crystal structure as that of the bone mineral, exhibits the highest degree of biocompatibility, but poor mechanical properties make them unsuitable for load-bearing applications. This project incorporates two vital technologies of the new millennium: biotechnology and nanotechnology to synthesize novel titanium based nanocomposites.A new powder processing technique, ultrasonic powder consolidation (USC), is proposed, which is a clean and energy efficient process without the inherent disadvantages of traditional powder metallurgy techniques. In this work, titanium/titanium alloy powders will be mixed with nano-HA powders and consolidated using ultrasonic waves into cylindrical composite pallets. The resulting compacts will be sintered using microwaves at a frequency of 2.45 GHz.The as-synthesized materials will be characterized in terms of phase content, microstructure, mechanical reliability, thermal stability and biocompatibility. The process parameters will be optimized.This work will be of great scientific and commercial potential and it is expected that the novel implants developed from these materials will offer a better quality of life to patients worldwide. This will attract new collaborators to Europe and will facilitate the development of novel ideas for the future that will benefit the European society
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'A Programme to Attract Postdoctoral Researchers to the Basque Country in any Research Field' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The aim of this project is to reinforce the  research potential of the European Research Area, and to consolidate the Basque Region as a Reference Point for excellence in research.Ikerbasque is a Foundation fostered by the Basque Government to strengthen the Basque Science System by means of attracting senior postdoctoral researchers. Ikerbasque currently manages two successful funding programmes running under the COFUND scheme, SmartBrain, offering full time positions for highly qualified and experienced researchers, and SmartFellows, providing short term sabbaticals for visiting researchers. In order to complement these two calls, Ikerbasque is implementing a novel complementary funding programme in the Basque Country for more junior postdoctoral positions to be supported for the next 5 years (from 2013 to 2018) through the current call of the Marie Curie COFUND programme.The new call to be launched on a yearly basis by Ikerbasque will host mainly incoming (non-national and non-resident researchers) postdoctoral researchers, and some reintegrating (national and non-resident) researchers will also be accepted if they comply with the eligibility criteria. The researchers can submit their applications in any research area.The selected researchers will have a temporary 5 year contract with all the freedom to choose their own research programme, as well as the host institution amongst the universities, research centres and different laboratories that have an agreement with Ikerbasque. They will be hosted in a research centre or university of their choice, where they will develop the research programme that best fits their individual needs, providing the best conditions for their personal objectives and for the development of a valid research project. Thus, WOLFRAM contribu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'self-assembled/healable Hybrid inorganic/Organic Polymer Electrolytes for sustainable electrochemical energy Storage'.

assistant: **Objectives**

Threatened by climate change, mankind is facing increasing demands for energy (generation, conversion, and storage) solutions to meet societal needs in a globalized economy. Energy and cost-efficient sustainable batteries will be instrumental in reaching climate-neutral (EU) continent by 2050 and UN SDG N°7 objectives by storing intermittent energy resources and enabling a green transport revolution. To address these grand challenges, the project HOPES targets safer-by-design self-healing All-Solid-State Alkali Metal Batteries (ASSAMBs), thus implementing a paradigm shift going beyond the ubiquitous Lithium-ion Battery (LiB) technology. Taking Lithium Metal Batteries (LMBs) as a post-LiB blueprint for ASSAMBs, Solid-State Hybrid Electrolytes (SSHEs) will be developed through a circular chemistry approach to enable LMBs, facilitating their inception onto the market. Within HOPES, we will i) develop mechanically, thermally, electrochemically tough self-healable and recyclable SSHEs through the colloidal self-assembly of nanosized building blocks consisting of inorganic core and end-group (vitrimer functionality)-functionalized Li+ conducting polycarbonate shell: Hairy NanoParticles (HNPs), and ii) establish multi-scale structure/property correlations with advanced characterization techniques at HNP, SSHE, and LMB levels, including synchrotron-based in situ and operando characterizations on operating LMBs. Depolymerization of HNP’s organic shell will trigger the disassembly of SSHEs, thereby authorizing the recovery & reuse of inorganic NP cores and (bio-based/sourced) cyclocarbonate monomers, but also the recycling & reuse of (NMC811) cathode and Li° anode to secure critical/strategic minerals and metals in EU. In line with roadmaps of the FET-Flagship Battery 2030+ initi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Structural study of a potassium channel, KirBac3.1, using electron microscopy' under Seventh Framework.

assistant: **Concept**

Ion channels, proteins that allow the passage of ions across the membrane, have crucial roles in many important physiological processes, such as nerve and muscle excitation, cell proliferation, hormone secretion and blood pressure regulation. Thus, defects in their function cause serious diseases. Moreover, their position on the cell surface, their heterogeneity and the localized expression in particular tissues make ion channels an attractive target for many drug therapies. The study of structures and functions of ion channels may elucidate their working mechanisms and allow an efficient drug design. Potassium channels are a family of ion channels involved in the diffusion of K+ ions through the cell membrane and widely distributed in most cell types. The inwardly rectifying potassium (Kir) channels comprise a superfamily of K+ channels that regulate membrane potential and K+ transport in many cell types. In order to completely elucidate how K channels open and close it is essential to obtain a structure for the same channel in both the open and closed states. The aim of the present project is to harness cryo electron crystallography to determine the structure of KirBac3.1 channel, at sufficient resolution to identify transmembrane helices and secondary structure motifs, with a view to understand how Kir channels open and close. In the case of KirBac3.1 open state, it is possible to produce relatively large 2D crystals that can be used to calculate the 3D structure from high tilted angle images. But the growth of these large crystals is not yet reproducible. So, for the present project, the applicant, Dr. R. De Zorzi, will join the research group of Dr. C. Vénien-Bryan of the Oxford University and will test various 2D crystallization conditions in order to produce reli