RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Novel conducting polymer composites for applications in medicine' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The goal of the PolyMed project is to develop a lasting collaboration between top class research teams in Europe and the US/Canada that fosters progress in the broad area of organic bioelectronics through progress in materials science. This will be realized via a cross-European, trans-continental network. Such a network is required as materials science is a discipline that has emerged first from a convergence of chemistry and physics, but has also recently embraced biological sciences, gaining cues from biological processes for design of novel materials. The PolyMed network will be a key driver for materials science through rapid identification and development of novel applications for existing and new materials, and will advance technological processes by building in enhanced capabilities in devices made from these materials; for example for sensing biological events or indeed acting as surrogates in case of biological dysfunction, i.e. in prosthetics. The combined expertise in PolyMed is essential to achieve a transformative impact.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'From mesoderm to hematopoietic stem cell commitment: cellular and molecular events occuring during mouse embryonic development'.

assistant: **Innovation**

Hematopoietic Stem Cells (HSCs) are at the origin of all blood cells needed throughout life. HSC transplantation is used to treat patients with blood related disorders. However, the number of HSCs available for clinic and research remains limited. The production of large quantities of HSCs in vitro, for example by reprogramming or transdifferentiation of somatic cells to a HSC stage, would be a good solution, but this remains extremely difficult. To overcome these problems, we must understand all the molecular and cellular events underlying the in vivo HSC formation. Because all adult HSCs are initially produced during embryonic development, it is clear that studying how HSCs are generated during ontogeny is of importance. We and others have demonstrated that specialized endothelial cells endowed with a hemogenic potential produce all HSCs. However, the exact anatomical site(s) of mammalian HSC origin and all steps leading to HSC production are unclear and highly controversial. In this ERC Starting Grant proposal, I describe comprehensive lines of experimentation to answer these fundamental questions. I first propose to develop a totally novel in vivo embryo rescue assay to unambiguously determine the exact site(s) of HSC origin. In this assay, candidate precursors will be tested for HSC potential by a novel in utero transplantation technique performed directly into developing HSC-deficient embryos. We will also determine how hemogenic endothelial cells generate HSCs (directly or via an intermediate population). Gene expression profiles and comparative analyses of these populations will be performed by RNA-Sequencing to determine the dynamic changes in gene expression and to identify key players in the HSC commitment process. I anticipate that our studies will significa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Eurocare 3 - understanding the reasons for cancer patients' survival differences in Europe' to be submitted under Fourth Framework.

assistant: **Abstract**

Since 1990, on the EU Concerted Actions EUROCARE-1 & 2, a network of population based Cancer Registries (CRs) has been established, aimed at studying survival and care of cancer patients in Europe. At present, EUROCARE is analysing survival trends from 3 million patients from 42 populations in 16 European countries, diagnosed in 1978-1989. EUROCARE showed that in Europe major survival difference do actually exist for several cancer sites. We are faced now with the problem of understanding the reasons of these differences. In principle, understanding cancer survival differences means to be able to distinguish how much they depend on different treatments, on treatment effectiveness because of early or late diagnosis, and just an early diagnosis (lead-time) without later death.In these perspectives, the aim of the present EUROCARE-3 project is threefold:1) Continuing to monitor cancer patients' survival by population-based data, insuring standardization, quality control, centralized facilities for analysis and dissemination of results. A continuous updating of survival data is necessary for furnishing guidelines for actual health policies. Updating of the EUROCARE data base is also expected to provide substantially new information on long term survival, survival trends, and survival of rare tumours;2) Monitoring patterns of care (diagnostic, staging and treatment procedures) and their relationship with survival. A number of CRs, representative of different European populations, should work in tight connection with clinicians to collect standardized clinicopathological information not routinely collected. The ultimate goal is to establish a stable registration network to monitor patterns of care on the cure of cancer, which leads to the third aim:3) Assuring proper interpre
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'EUROpean CITIes platform for on-line transaction services' (EURO-CITI) under Fifth Framework.

assistant: **Objectives**

The EURO-CITI project aims to specify, develop and test a common architecture and related services targeting the public sector. The proposed services include tele-voting, electronic submission of forms and tele-consulting. Tele-voting will be used for opinion polls and petitions that can be initiated by both the local authorities and citizens aiming to reinforce the concept of direct democracy. The proposed architecture will integrate and where appropriate enhance key technologies for security, authentication/authorisation, data description, user-centred interfaces, etc. The resulting EURO-CITI platform will be dynamically re-configurable to allow for example simultaneous voting on the same problem at geographically distributed areas. The trials will be supported by a generic methodology for process re-engineering and will take place in three major European cities.OBJECTIVESThe main objective of EURO-CITI is to develop and demonstrate a set of new public transaction services, namely tele-voting, electronic submission of forms, and tele-consulting, that can be accessed via the Internet and GSM. These services will be designed to improve the efficiency of local authority, reinforce the concept of direct democracy and foster collaboration between local authorities at all levels (regional, national, European). More specific objectives of EURO-CITI include: 1. To specify and develop a common architecture that supports among others data security, authentication/ authorisation and dynamic configuration. 2. To develop the new transaction services and deploy them on three European pilot sites. 3. To develop and test a process re-engineering methodology that allows local authorities to fully exploit the developed transaction services.DESCRIPTION OF WORKThe work is divided into th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Hybrid DNA-protein nanopores with large and uniform pore sizes' under Horizon 2020.

assistant: **Concept**

This proposal aims at developing novel hybrid DNA-protein nanopores with well-defined, uniform channel sizes, to advance fundamental studies on transport across membranes and to enable the development of new biosensors and progress towards creating artificial cells and tissues. Currently used protein nanopores either have a limited cargo capacity, which is set by their internal diameter, or they are heterogeneous in size and sometimes incompletely assembled. I propose to use DNA origami nanostructures as scaffolds for barrel- and ring-forming peptides of alpha-haemolysin and ClyA/Wza to create hybrid pores with larger and uniform pore sizes. These hybrid pores have the advantage that they are fully biocompatible and retain the potential for genetic and chemical engineering at the level of the DNA and proteins through the use of nucleotide recognition sequences and functionalised amino acid residues. By systematic characterisation of the hybrid nanopores in the controlled environment of droplet interface bilayers using single-channel current recordings and fluorescent detection of transport across membranes, the proposed hybrid nanopores will provide valuable insights into membrane transport and potential applications in biotechnology and medicine.


**Keywords:** nanopores, alpha-haemolysin, protein engineering, DNA-origami, membrane transport, biosensors
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Novel Electron Beam Surface Sculpting for Efficient Heat Exchange' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

By combining a new surface engineering process with state-of-the-art thermal modelling, significant design and performance improvements to heat exchangers for electronic and electrical systems can be made. The surface designs created will not only provide an increase in surface area (allowing for smaller size heat exchanger packaging), but also enable ‘designed’ flow over a surface (which will enhance its heat transfer potential). These benefits will place a consortium of SMEs in a position to compete against competition from countries with cheaper labour overheads and the potential for charging a price premium for specialised systems, increasing their profitability and generating value in the EU economy.There is a drive towards miniaturisation of electronic devices as well as requirements for higher power applications. The size of the heat exchangers necessary is the limiting factor for package size. By combining a European surface processing technology with complex computational fluid dynamics (CFD) modelling, heat exchange surfaces will be customised and optimised. The result will be optimised, efficient heat exchangers for the next generation of electronic devices.Conventional heat exchanger manufacturing processes are extensively developed and only small future efficiency improvements are likely to arise. The Heat-Sculptor project will generate an enabling technology that will increase the performance of heat exchangers by >23%. Until now, designs have been constrained by production technologies e.g. machining or chemical etching. The new electron beam surface engineering process, Surfi-Sculpt®, has the capability to rapidly create complex ‘Heat-Sculptor’ surface geometries that are not possible with existing techniques.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Costs of variable incubation conditions in a passerine bird' (2002-2006) under Sixth Framework.

assistant: **Objectives**

This proposal seeks funding for a two-year postdoctoral Marie Curie EIF fellowship in animal ecology, focusing on costs of variable incubation conditions to offspring and parents in birds. The project aims to study how incubation conditions could affect the developing embryo and the incubating parent through a series of experiments where clutch sizes are manipulated.The blue tit will be used as a model organism, and the fieldwork will be conducted in Loch Lomond NP, Scotland, UK. The postdoctoral work will be carried out in collaboration with Professor Pat Monaghan and Dr Ruedi Nager in the Ornithology Group at the Institute of Biomedical and Life Sciences, University of Glasgow, UK.Working in this group provides an optimal environment for me to further develop my research on avian reproductive ecology and evolutionary processes, and for learning new research methods. The hosting institution internationally renowned within the fields of avian life history and reproductive ecology provides an enriching and stimulating academia for intellectual development.Building upon my previous research experience with field studies of birds and ecological hypothesis testing, the study will add new aspects to my research profile, e.g. with the incorporation of physiological and endochrinological studies for use in an ecological context. It will also incorporate the use of novel field instrumentation equipment currently being developed at the host institution.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Promoting real life Observations for Gaining Understanding of road behaviour in Europe' to be submitted under Seventh Framework.

assistant: **Abstract**

The number of road fatalities in Member States is decreasing too slowly to meet the EU-targets. A new generation of measures is needed, underpinned by a new generation of research methods. Recent technology developments allow for this: naturalistic observations. This means that road user behaviour is observed unobtrusively in a natural setting for a longer period of time. This technique allows for analysing the interrelationship between road user, vehicle, road and other traffic in normal situations, in conflict situations and in actual collisions. Results will lead to a better understanding of road safety and help to realise an intrinsically safe road transport system, including in-car technology, self-explaining roads, driver training, etc.The main objective of PROLOGUE is to prove the feasibility and usefulness of a large-scale European naturalistic observation study. The project aims at road safety researchers and other stakeholders including car industry, insurance companies, driver training and certification organisations, road authorities, and governments. Whereas road safety is the main motive, the project will also look at the relevance for environmental issues, e.g. CO2 emissions, and traffic management.Based on inventory studies, a series of small-scale field trials, and close involvement of user groups and stakeholders, PROLOGUE will result in recommendations and an outline for a large-scale naturalistic study, dealing with research questions, methodology and technology for data collection, data storage, data reduction, data mining and data analysis. Communication and dissemination to all potential stakeholders are vital to gain their support for and involvement in a large-scale European study.The PROLOGUE consortium consists of 9 partners institutes, is wel
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for '5th International Conference on Hydroscience and Engineering, Warsaw University of Technology, Warsaw, Poland, September 18-21, 2002' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The 5th International Conference on Hydroscience and Engineering is to be held from 18 to 21 September, 2002 in Warsaw, Poland. The Conference is organised by the Warsaw University of Technology, Faculty of Environmental Engineering, under the patronage of H.E. the Minister of Environment of Poland and under the sponsorship of the International Association for Hydraulic Research (IAHR). The ICHE-2002 will extend the series of biennial conferences started in Washington, D.C. (1993), and continued in Beijing (1995), Cottbus/Berlin (1998) and Seoul (2000). These conferences have acted as a forum for reporting the latest advancements, reviewing the state of art, and exchanging ideas and experiences in the field of hydro-science and hydro-engineering.Special emphasis has been laid on the transfer of technologies (including IT) and expertise among research scientists, practice engineers, management planners and policy makers. The principal objective of ICHE-2002 is to further and promote this co-operation and to continue the highly useful exchange of new ideas among the Conference participants representing theory and practice of technical, economic, social and environmental aspects of integrated water management. The Conference central theme is hydro-science and engineering in the changing world; challenges, opportunities and constraints. Because of the Conference venue, special emphasis will be laid on water-related issues special to the quickly developing transition economies. The Conference topical areas include: A Basics and Modelling Concepts, B Sub-Surface Hydraulics, C Hydrology and Environmental Hydraulics of fluvial Systems, D Hydraulic Structures, E Hydraulic of Coastal and Maritime Engineering, F Water Management Systems, G WEB bases engineering and education.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'EURIAS Fellowship Programme' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The European Institutes for Advanced Study Fellowship Programme (EURIAS) was created in 2010. For the 2014-2019 period, with the support of the European Commission, the Programme could offer 212 ten-month incoming fellowships in a consortium of 16 Institutes for Advanced Study (IAS) located in 12 European countries. The Programme is open to all fields in the Humanities and Social Sciences, as well as to other disciplines. The great diversity of the academic and cultural offerings of IAS provides a unique spectrum of choice to candidates.The IAS offer research and professional opportunities that are complementary to universities and research centres. They create multi-disciplinary and multicultural learning communities, open intellectual spaces where fellows —released from their teaching and academic commitments— conduct bottom-up research with the greatest possible freedom and with the IAS support. These learning communities provide permanent intellectual stimulation as a result of the daily encounters among the fellows from a wide range of disciplines, cultures and scientific traditions. And the many activities carried out by the researchers with the support of the host IAS (in terms of work conditions, organisation of events and academic networking) further widen their intellectual, scientific and professional horizons. IAS constitute experimental spaces where, for an academic year, researchers can stray from the customary paths of their disciplines and nurture new transdisciplinary collaborations to be developed. This one-year rejuvenating professional experience gives them a fresh perspective on their research and a boost to their careers, generating long-tem impact on the fellows’ career and research back in their home institution.EURIAS contributes to structuring
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'AUTONOMOUS ACQUISITION OF VISUAL REALITY MODELS FROM REAL WORLD SCENES' in the context of a Fourth Framework call.

assistant: **Objectives**

A variety of commercially available technologies exist for capturing shape. Laser ranging devices can build up a reasonably accurate range image of a sample in few minutes. However, this image is usually based on a single view and needs a laborious human effort to be converted into a 3D representation.This project addresses the autonomous acquisition of virtual reality models from real world scenes. There is a considerable demand for graphical or metric models by many industries. Such models can be used for marketing, reverse engineering, and computer aided design. Animation and entertainment applications are widely used.In this project, two sensor platforms for scene acquisition will be developed: a colour/range sensor on a robot arm and a mobile platform with an onboard video camera.