RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Strain-Free All Heusler Alloy Junctions' in the context of a Horizon Europe call.

assistant: **Objectives**

Spintronics is anticipated to replace current semiconductor-based memories and sensors based on fast-operating times (< ns) and low power consumption (<pJ per read/write operation). The spintronic devices typically consist of a magnetoresistive junction with a free ferromagnet/oxide barrier or non-magnet/pinned ferromagnet trilayer and may suffer from edge-domain formation and leakage current through the barrier by further miniaturisation (<10 nm in cell diameter). To avoid such obstacles, antiferromagnetic spintronics has recently been developed by introducing spin-orbit torque which can reduce the power consumption by over two orders of magnitude but contain critical raw materials. In this transformative project, we aim to develop a ferrimagnetic Heusler-alloy film, in which the magnetic properties will be controlled by substituting the constituent element to achieve compensated ferrimagnetism (effectively the same as antiferromagnetism) sandwiched by weak and strong ferrimagnet in a single-step deposition. This will be achieved based on our Heusler-alloy database developed recently through existing collaborations. The selected alloy(s) without using critical raw materials will be grown by dedicated combinatorial sputtering under low pressure and characterised by conventional structural and magnetic analysis as well as non-destructive imaging we have developed and synchrotron-beam imaging at the Paul Scherrer Institute. Such atomic engineering can offer a new way for material development for low-power electronics. The simplified growth process for a junction without any interfacial scattering is adoptable for future spintronic devices as will be demonstrated using the 200-mm-wafer production line at IMEC by the end of this project. Hence this proposed project will rev
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Brain-inspired Resistive Artificial Ionic Neural Networks based on Crossbar-arrays of Conic Channels'.

assistant: **Innovation**

The energy consumption of machine learning (ML) is doubling every 2 months, outpacing  global energy production within the next decade. Neuromorphic computing, in particular, memristive crossbar arrays have shown energy reductions of 2 orders of magnitude in ML. However, the training is typically performed on conventional computers, leading to significant energy losses. Conical microfluidic channels have shown promise as volatile memristors, and there has been early progress toward achieving nonvolatile behavior in these channels. However, the conductance of the channels can only be increased and not decreased, which is crucial for ML. In BRAIN-CCC I will study the interactions of chemically functionalized surface groups, chemical shocks, pressure gradients and electric impulses in simulations to achieve reversible nonvolatile dynamics of the conductivity in these channels. From this, I will develop a model for the conductivity dynamics. To test the feasibility of performing ML training directly in hardware, without relying on conventional computers, I will first design and assemble a prototype using variable resistors. Subsequently, I will replace the variable resistors with iontronic channels and measure the real world advantages of this approach, continuing a collaboration with an experimental group.BRAIN-CCC will be conducted at Utrecht University. Knowledge transfer in BRAIN-CCC will be bidirectional: The host contributes expertise in soft matter systems and ML, while I provide knowledge of designing and building electronic hardware and interdisciplinary knowledge transfer. The combination of these skills is crucial to realizing a prototype of ML hardware, based on iontronic channels. The project combines interdisciplinary approaches from physical chemistry, electr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Deciphering the molecular mechanism of inflammation orchestrated by keratinocytes during Staphylococcus aureus infection in the skin' (Staph-in-Skin).

assistant: **Concept**

The skin provides a physical and immunological barrier to external environment and its homeostasis depends on interactions between keratinocytes, peripheral nerves, immune cells and microbiota. One of the bacteria that can colonise skin is Staphylococcus aureus and it can be part of healthy skin or pathogen causing skin infection. Importantly, in atopic dermatitis patients, which suffer from impaired skin barrier and microbiota dysbiosis, S. aureus is associated with severity of flares and exacerbation of inflammation. The inflammatory loop in the skin depends both on host and pathogen factors, but it is not fullyelucidated how this interaction is regulated.The proposed project will investigate novel mechanisms regulating the inflammation induced by S. aureus skin infection. The main focus will be on molecular mechanisms and regulation of pathogen sensing by keratinocytes. First, murine model of topical skin infection will be used to characterise how keratinocytes orchestrate immune response. Then, it will be examined in detail which S. aureus virulence factors induce inflammation in keratinocytes using different laboratory and clinical S. aureus strains. Finally, the role of characterised virulence factors and immunomodulators secreted by keratinocytes will be investigated in keratinocyte-immune cells interactions. To achieve the goals of this project, proteomics, next-generation sequencing, biochemistry, molecular biology and immunological assays will be applied.Overall, this project will contribute to greater understating of S. aureus-host immunity interactions with particular focus on regulation of keratinocyte inflammatory response. Moreover, identified novel signalling molecules in the skin and virulence factors of the pathogen can be explored in novel skin inflam
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Holographic optical elements (hoe) for high efficiency illumination, solar control and photovoltaic power in buidings (high efficiency hoe's)' to be submitted under Fifth Framework.

assistant: **Abstract**

The solar radiation is the major renewable source of power. Integration of (light directing) holographic optical elements (ROE) into the envelope of the build environment offers high efficiency use of this source. The control of solar power by redirecting the direct and indirect light of the sun will give a broad scale of applications with a high potential for energy saving. We will produce Hoe's for illuminating remote room areas with high quality diffuse or direct light of the sun as well as for efficient solar control to reduce cooling loads and for light concentrating system to enhance effectiveness of photovoltaic panels. The application of Hoe's will lead to an integrated approach to make use of the solar power for building performance. This provides a major step toward a sustainable energy solution for buildings by reducing the energy intensity on demand.Project Glossary-Report on harmonisation of procedures-Established industrial production technology for HOE's-Holographic Optical Elements for light directing and sun shading (Holographic films in glass) using White-Light Holograms and Grating-Holograms Guideline for HOE system application (Catalogue for different types and functionalities of HOEs). Test rigs for HOEs systems in Dortmund, Athens and Southampton for sun shading and light directing Results of simulation studies, laboratory performance tests and field tests with HOEs Project webpage E-Coaching portal for Daylight in architecture with focus on HOEs (opened for the project partners). A skript on Daylight in architecture and HOEs Technical Reports, Management Reports.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'High-Power Ultrasound technology to disrupt the honey industry and revolutionize beekeeping sector' (LIQUAM) under Horizon 2020.

assistant: **Objectives**

Crystallization is a natural phenomenon that takes place in honey in few weeks after extraction, caused by its high concentration in sugar crystals. Such crystallised honey becomes opaque and semi-solid. This unavoidable tendency is a serious problem that severely affects honey marketing due to handling issues and because most consumers only purchase liquid honey due to the widespread wrong belief that crystallized honey is spoiled or adulterated. Consequently, retail honey is heated to 80ºC for delaying crystallization +12 months post-processing and facilitate packaging. However, this thermal treatment has been proved to be detrimental to the quality and healthy properties of honey, since it losses its desirable heat sensitive enzymes and valuable antioxidants, therefore losing the abundant medicinal properties associated with it. In response to consumers’ demands for fresh and healthier food, a clear need exists in honey industry for a cost-effective non-thermal processing alternative. Sonicat System has developed a disruptive patented system, based on the use of High-Power Ultrasounds, which allows reducing the content of sugar crystals up to pasteurization levels (0.3%), without impacting on enzymes, pH, conductivity, nor Hydroxyl-Methyl-Furfural concentration, a key indicator globally used to measure honey’s quality. Our skilled team has invested more than 5 years to develop the functional prototype (allows processing up to 100kg/h) which has been validated during months at clients’ premises. We were awarded with a SMEInstrument Phase1, which allowed us to carry out the feasibility study. We are applying to Phase2 to scale-up LIQUAM reactor to industrial rates, while improving the electronics and its usability. With LIQUAM, our clients will be able to sell premium
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Applications of liquid crystals for advanced nanoscale devices and optics' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

A coordinated and well defined effort of experimental, applied and theoretical research groups will be organized to obtain a better understanding and efficient control of self-organization and surface properties of novel liquid crystalline nanoscale systems, such as 3D periodic anisotropic nematic colloids , micro- and nanoemulsions , holographic gratings and liposomes. The study of nanoscale and surface properties will be performed with novel surface sensitive techniques, such as AFM, STM, DLS, NMR, EPR, completed with modeling and simulations. The project involves a coordinated collaboration of 37 partners in EU and NAS .
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Testing the Evolutionary Consequences of Haploid Selection in Animals' (SELECTHAPLOID) under Horizon 2020.

assistant: **Objectives**

Selection occurring during the haploid gametic phase of any sexually reproducing eukaryote may have far-reaching consequences for major biological processes. Selection acting on a haploid genome results in efficient removal of deleterious alleles and rapid fixation of beneficial alleles, which in turn affect adaptation, genetic load and the evolution of recombination rates. Despite their potential importance, we know surprisingly little about the genetic processes occurring during the time window after meiosis until the fusion of male and female pronuclei. This is particularly true for haploid selection in the gametes of predominantly diploid animals. Male gametes (sperm) are produced in vast numbers but only few fertilise eggs and therefore offer a strong opportunity for selection. A prevailing view that such haploid selection is of minimal consequence in animals has been recently overturned by evidence from our lab, which revealed strong links between sperm phenotype and offspring fitness, as well as sperm phenotype and its haploid genotype. The genetic mechanisms underlying these observations are currently poorly understood. In this project, I will tackle three key questions arising from these recent findings: i) How strong are purifying and positive selection during the haploid phase? ii) What are the mechanisms maintaining genetic variation in genes expressed during the haploid phase? iii) How does haploid selection affect the interaction between male and female gametes? By combining carefully designed innovative experimental approaches with cutting-edge single-cell genome and transcriptome sequencing technologies, this project will provide entirely novel insights into the process that is shared by all eukaryotic life. Findings from this project will illuminate not
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Hard Material Small-Batch Industrial Machining Robot', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Hard materials machining has recently attracted great attentions from the advanced industries, in particular, the European automotive, the aerospace and the biomedical industries. However, the existing technology failed to provide these industries with a cost efficient solution to cope with small-batch production of large and complex-shaped products. The project Hephestos, with its focus on developing sophisticated methods in robotic manufacturing, shall give rise to a cost-efficient solution in hard materials machining for this small-batch production of highly customized products through the application of industrial robots.<br/>Hephestos will develop a paradigm that shall provide standard industrial robots with break-through techniques in production planning, programming and real-time control system. Based on established computer-aided-manufacturing frameworks, Hephestos will optimize production planning through the automatic generation of robotic program, taking into account specific robot signature i.e. robot system kinematic and dynamic characteristics, as well as models of processes (milling, grinding, polishing etc.), that are essential for the robotic application in hard material machining. To cope with small batch production time scales, real system data obtained by means of advanced sensor techniques will be integrated in the planning to improve efficiency. Human experience and expertise will also be involved in the entire planning process. Real-time strategies based on impedance and force control for the interactions between robot and the cutting of material, will take into account uncertainties and critical chattering effects in hard metal machining. Force-feed control should ensure high quality and precision in grinding and polishing operations and thus, ex
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Europe, the United States and the Crisis on the KORean Peninsula: Between a Rock and a Hard Place' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The objective of the EUSKOR project is twofold: firstly, to explore why the EU has so far been unwilling and incapable of becoming a credible political and security actor in North East (NE) Asia despite its declared intensions, trade power and experiences applicable for the region; secondly, to examine whether and how the EU could upgrade its political and security role in NE Asia by its increased strategic engagement on North Korea. The EUSKOR first examines the new ways in which the EU (and its Member States) can ‘download’ its foreign policy preferences and help reach denuclearization on the Korean peninsula and peace settlement between the ROK and DPRK (WP 1). Second, the EUSKOR project explores how by ‘downloading’ the EU’s preferences and policies to the North Korean issue could the EU ‘upload’ an upgraded strategic standing in NE Asia (WP 2). Given the EU’s push for free trade, particularly at the time of a growing American protectionism, WP2 also investigates whether and how the EU could better link its political and security interests with its trade leverage. The EUSKOR project’s highly topical empirical findings are complemented by theory-building through looking at who/what drives EU foreign policy and why and whether diffusion of European ideas and policies could ‘travel’ beyond Europe, hence making the link between EU internal governance and EU foreign policy. Drawing on extensive series of semi-structured interviews to be conducted in Berlin and during short visits in NE Asian capitals, the EUSKOR project is cross-sectoral and multidisciplinary, informing at least three fields (international relations, comparative politics and political economy). The KOREU project is based at the Center for European Integration at Free University Berlin and supervised by P
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Regulation of cell division by alternative splicing' (2007-2013).

assistant: **Innovation**

The complexity of the mammalian proteome is far more extensive than can be explained by a simple one gene: one protein paradigm. The use of alternative splicing (AS) is emerging as a core regulatory mechanism, in a similar way to whether a specific gene is transcribed or repressed, or a protein is degraded or stabilised. Also like both transcriptional and post-translational control, it seems that almost every gene in the human genome undergoes AS. Despite this, the role of AS in a fundamental cellular process, such as cell division is still poorly understood. This proposal aims to tackle this problem by assessing the role of AS in cell division.The recent identification that the machinery involved in splicing, the spliceosome, is regulated by post-translational modifications (PTMs) during cell division strongly suggests AS, alongside PTMs, may have a core regulatory role in mitosis. This project proposal is therefore timely and will gain insights into this universal cellular process. I will use a multidisciplinary approach of combining next-generation mRNA sequencing in human cells to take snapshots of multiple stages of cell division with validation using proteomic datasets. Further validation of individual candidates will be done by high-throughput fluorescence microscopy to discover potential novel regulators of cell division. Furthermore, I will assess the segments removed by AS for functional modules known to modulate protein abundance and stability. A web-based relational database will be developed to disseminate our findings to the scientific communityThis proposal will assess the occurrence of splice variants during mitosis and aims to discover new regulators of cell division. The interdisciplinary approach and the data produced in this proposal will be highly b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Accurate Nuclear Data for nuclear Energy Sustainability' in the context of a Seventh Framework call.

assistant: **Objectives**

According to the recent publications of the European Technological Platform for a Sustainable Nuclear Energy (SNETP) (Vision report and Strategic Research Agenda) the sustainability require the combination of the present LWR, future Advanced Fast reactors and the waste minimization in closed cycles with Partitioning and Transmutation. To implement these new nuclear systems and their fuel cycles it is necessary to improve the accuracy, uncertainties and validation of related nuclear data and models, required for those systems but also for the experimental and demonstration facilities involved in the their validation. The project will include new nuclear data measurements, dedicated benchmarks, based on integral experiments, and improved evaluation and modeling specifically oriented to obtain high precision nuclear data for the major actinides present in advanced reactor fuels, to reduce uncertainties in new isotopes in closed cycles with waste minimisation and to better assess the uncertainties and correlations in their evaluation.