RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Role of Progesterone Receptor Membrane Component-1 in oogenesis and mammalian fertility' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Infertility is a major problem that affects domestic mammals and declining fertility represents an obstacle in maintaining profitability of dairy farms in Europe and worldwide. Since declining fertility of cattle is mainly due to the poor quality of the oocytes, defining the factors and mechanisms that affect oocyte quality, is essential for improving female fertility. In particular, basic knowledge of which proteins within the oocyte regulate meiosis, oocyte fertilizability and early embryonic development would be advantageous. Based on our preliminary data, we propose that Progesterone Receptor Membrane Component 1 (PGRMC1) is one of the key factors that regulate mammalian oocyte quality. This hypothesis will be rigorously tested by determining 1) whether PGRMC1 plays an essential role in maintaining the ability of bovine oocytes to complete meiosis, undergo fertilization and develop to an healthy embryo in vitro, by genetically manipulating the levels of PGRMC1 within the oocyte, and 2) PGRMC1’s mechanism of action by identifying its interacting proteins within the oocyte.The scientific program is directly linked to the studies that the candidate has conducted during her period of mobility at the University of Connecticut Health Center (USA) and should result in important discoveries in the field of reproductive biology. If granted, this study will contribute to the improvement of the quality of European research and will improve significantly the lifelong training and career development of the applicant, providing the opportunity to capitalize in Italy on her experience on this promising topic.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Death receptor signalling in tumour immune editing'.

assistant: **Objectives**

During tumour development there is a bi-directional communication between cancer cells and immune cells; the process termed tumour immune editing. The impact is reciprocal, shaping both the visibility and susceptibility of the tumour to immune eradication as well as the ability of the immune effector cells to recognise and launch an immune response against  tumour cells. Death ligand-death receptor signalling is a key mechanism to kill tumour cells during the early stages of tumour development (tumour immune surveillance). However, the role of this signalling pathway in evolved tumours is poorly understood. Recent pioneering results from DISCOVER consortium members highlighted non-canonical signal tranduction pathways mediated by death receptors, which regulates both tumour cell behaviour (motility, invasion) and effector immune cell function in the tumour microenvironment. The aim of the DISCOVER proposal is to bring a collaborative research network together to determine the role of death ligand-death receptor signalling in tumour - immune cell interactions. The DISCOVER  programme will determine how non-canonical signal transduction pathways driven by death receptors control effector immnue cell functions and tumour cell behaviour. The outputs of the research will be used to develop informed therapeutic strategies to interfere with non-canonical death receptor signalling in order to re-activate anti-tumour immune attack and sensitise tumour cells to this attack.The DISCOVER proposal will integrate the research activity of seven beneficiary organisations from 5 European countries, including 3 companies and create a framework for knowledge and reagent exchange for early stage and experienced researchers. The consortium will bring together scientists from immunology and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Topological Effects in Bosonic Lattices'.

assistant: **Innovation**

Controlling and manipulating quantum matter is a fast-growing research topic that could revolutionise technology and influence many aspects of our daily life. A promising step in this direction is to use topological concepts to tune physical properties of matter and to exploit novel phenomena useful to build new physical devices. In the last decade, topology have been extensively studied in the context of quantum many-body systems, a revolution that has led to the discovery of the topological insulators. Similarly, the Fubini-Study metric has just begun to show its physical meaning and role played in some quantum phenomena, but a lot more remains to be investigated. In this Action, I will study how topological and geometrical effects emerge in the physics of bosons in lattices. I will first address the geometrical contribution in the dynamics of two-body bound states, and then I shall identify conditions for enhancing inter-particle interactions on a full many-body system. I will apply these findings on photonic lattice systems and investigate how non-trivial quantum geometry and topology can lead to novel lasing phenomena. The nature of the work, being based on a combination of expertise, will have a strong interdisciplinary character. The research will be done at Aalto University in the Quantum Dynamics group led by Academy Professor Päivi Törmä, with the unique and exciting opportunity for me to work on the theory in a side by side collaboration with the experimentalists of the group. The expected impact of this research will advance our understanding of the topological properties of bosons in lattices, towards the exploration of geometrically-induced ultrafast lasers and strongly correlated topological fluids of light.


**Keywords:** topological phases of matter, F
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'SUrface waves in smart Radio Frequency EnviRonments' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Reconfigurable intelligent surfaces (RISs) have emerged as the new wireless communication research frontier with the goal of realizing smart and reconfigurable radio propagation environments via passive and tunable signal transformations. Featured by orders-of-magnitude lower hardware and energy cost than traditional active arrays and yet superior performance, RISs are the new driving technology for future 6G wireless networks, especially for enabling them to migrate to higher frequency bands. RISs will fundamentally transform today’s wireless networks with active nodes solely to a new hybrid network comprising active and passive components co-working in an intelligent way, so as to achieve a sustainable capacity growth with low and affordable cost and power consumption. Current wireless networks based on RISs are, however, based on the free-space communication (FSC) paradigm: The radio waves occupy the entire space, naturally propagate in all directions, and are reflected, refracted, and scattered after hitting objects. In contrast with FSC-based RISs, an emerging technology for enabling reliable, energy-efficient, and interference-free communications in indoor environments is surface wave communication (SWC). Surface waves glide at the interface of materials and their propagation is inherently confined on their surface. Compared with FSC, the unique advantages of SWC are a much more favorable pathloss, a much easier interference management, and an inherent low probability of intercept if appropriate anti-wiretapping schemes are used, since the radio waves propagate along surfaces without leaving them and creating unwanted interference. Supervised and trained by a team of five internationally renowned researchers from academia and industry, Surfer’s experienced researc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'New Techniques for Secure Computation'.

assistant: **Concept**

Secure computation is a general-purpose tool for processing sensitive data without compromising itsconfidentiality or integrity. In recent years, significant research efforts have been invested in optimizingand implementing secure computation protocols and related cryptographic primitives such as fullyhomomorphic encryption and program obfuscation.The proposed project will explore new techniques for secure computation and related primitives.The new techniques are expected to enhance the asymptotic and concrete efficiency of current solutionsand extend the known relations between secure computation and other problems in cryptography andcomputational complexity theory. The research will span the following directions:• Succinct secure computation via homomorphic secret sharing, exploring new research directionsthat were opened by recent works of the PI;• Protecting protocols against malicious parties, with relevance to efficient general-purpose programobfuscation;• Protecting protocols against general information leakage


**Keywords:** Secure multiparty computation, computational complexity theory
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'OLIGOPEPTIDASE INHIBITORS IN BRAIN FUNCTION AND DYSFUNCTION: TOWARDS NEW THERAPEUTIC STRATEGIES FOR NEUROPROTECTION' in the context of a Seventh Framework call.

assistant: **Objectives**

At present more than 5 million people in the EU suffer from dementia and other neurodegenerative diseases and that number will grow as the average age of the population continues to increase. The efficacy of current medicines is limited and new therapeutic targets are sorely needed. Several independent lines of evidence have established an important role of prolyl oligopeptidase (PREP) in brain function and dysfunction. Aberrant PREP activity is involved in the progression of neurodegenerative disorders and PREP inhibitors are being developed for the treatment of memory and cognition deficits. Now a consortium of expert scientists from 8 academic institutes and 3 SME's come together for 4 years in this NEUROPRO project to boost European research aimed at 1) unravelling the biological role of PREP and PREP-like proteins in neuropathology, 2) determining the mode of action of PREP inhibitors and 3) firmly establishing their therapeutic potential. Specialists from different disciplines – cell and molecular biology, enzymology, chemistry, crystallography, biology and pharmacology – will work in a concerted and focussed way to achieve the goals using 6 work packages concentrating on PREP-regulated pathways in health and disease, PREP substrates, inhibitor target identification, drug development and validation, and generation of specific cell lines and animal models of neurodegenerative diseases. The SME’s involved are leaders in PREP inhibitor development and peptide analysis, and have in the past already brought novel therapeutics on the market. By the end of the project we expect to have proof of concept that PREP inhibition is a valid therapeutic target which will ultimately lead to new methods for the early detection, prevention or restoration of PREP-related neurodegene
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'European virtual institute for functional genomics of bacterial pathogens'.

assistant: **Objectives**

Bacterial infections remain a major cause of disease and mortality in humans and animals throughout the world, he study of infectious disease, which is established in Europe in form of various national research centres and by a considerable number of lab oratories, needs a multidisciplinary approach that brings together the different disciplines of molecular biology, immunology, cell biology and structural biology. Although scientific collaborations within Europe have been established to a some extent, t here is a pressing need for more permanent links and structures between the different disciplines. This task will be accomplished by the network of excellence (NoE). Accordingly, it is the aim of the NoE EPG to form an alliance of the existing capacities in Europe. The three main objectives of EPG are: 1) stimulation of multidisciplinary collaborative research activities; 2) creation of an European training facility for teaching of scientists and physicians; 3) foster biotechnological applications and t echnology transfer to European companies. The expected deliverables are innovations in the areas of diagnostics, drug and vaccine development The NoE brings together some of the best European groups involved in genomics of bacterial pathogens to establis h an internationally competitive platform of knowledge, expertise and technology. The NoE will promote discoveries leading to the development of innovative diagnostic tools, to the discovery of novel anti-infectious agents and their targets, the identifi cation of new antigens and the deciphering of host defence mechanisms. The NoE will integrate epidemiological, basic and clinical researchers carefully considering ethical and gender issues. It will also establish a higher standard in the teaching infect ious diseases. T
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'enabling Consumers to Learn about, Engage with, Adopt and regulate  Renewable energy technologies 2.0'.

assistant: **Innovation**

CLEAR 2.0 - enabling Consumers to be Engage with and Adopt Renewable energy technologies. 2.0- is a new project that builds on the learning of an EU funded project IEE13-588 CLEAR.It will actively guide consumers in the energy market and enable them to be more aware, active players, save money and easily become ""prosumers"".  The Consortium will accompany consumers through all the stages leading to the purchase and the correct efficient use of domestic renewable and low-carbon energy technologies. The CLEAR 2.0 project will focus as well on changing behaviour and optimisation of existing installations. The main needs of a home, including heating/cooling and electricity production (including storage and monitoring systems) will be addressed through a consumer-centric approach and actions that will lead to the changing behaviour and form collective consumer groups to support the purchase of renewable energy technologies such as photovoltaic installations, batteries, pellet stoves and heat pumps for heating and cooling.The three major barriers (awareness, behaviour and price) to the investment in RES will be directly addressed, having as a result a higher consumer engagement.BEUC and the consumers organisation focus their advocacy work on relevant legislative developments in order to overcome existing barriers and facilitate consumers’ participation in the energy market. It will distil policy lessons to create a favourable and stable national and European policy framework for the benefit of all European consumers.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'THE NEW ENVIRONMENTAL ENERGY STORAGE' in the context of a Horizon 2020 call.

assistant: **Objectives**

Eco-Tech Ceram (ETC), a young company founded in 2014, is specialized in thermal storage, energetic efficiency, industrial wastes recovery high valuation and advanced materials characterization.With their new technology, ECO STOCK, ETC aims to develop new eco-efficient, transportable and modular thermal storage solutions.The first step is to collect industrial wastes, such as coal fly ashes, and transform them into refractory ceramic. This exploitation of industrial waste induces a reduction in the exploitation of raw materials, while producing an eco-efficient material providing effective heat storage.Subsequently, the second challenge of the ECO STOCK project is to use those ceramics, composed of industrial wastes, in order to develop a thermal energy storage unit (TESU) solution. This solution proposes a modular, plug&play and transportable unit capable of valuing industries’ loss heat and power, creating in the same time a reduction in energy costs.Indeed, using those inorganic secondary raw materials, transformed into refractory ceramic, it has the advantage to propose a low cost storage material and exploit the “below 1000°C temperatures” recycling market.To summarize, the company proposes the whole value chain, from the material recovery to the commercialization of the storage installations, through unit storage manufacturing.Therefore, the company has the objective to create a green circular economy, using this whole value chain, in order to counteract the worldwide energy crisis and ecological threat.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Exploiting RESonant processes to understand CORrelations'.

assistant: **Concept**

Spectroscopy is one of the fundamental tool in condensed matter physics, materials science and nanoscience. Resonant spectroscopies, like Resonant Inelastic X-ray Scattering (RIXS) and angle resolved Resonant PhotoEmission Spectroscopy (RPES), offer invaluable information on the system under investigation, being able to probe different types of excitations, from electron-hole pairs (excitons), to spin-flip, to collective excitations, to orbital and magnetic excitations. This proposal aims at improving the present theoretical description of these two powerful spectroscopies, in order to gain a better understanding of moderately correlated systems and, on the long term, to offer a future tool to describe resonant spectra of strongly correlated systems. The proposal relies on the combination of efforts between the candidate (whose experience is mainly in X-ray spectroscopy) and the community working in low energy excitations mainly via many body perturbation theory. Such joint effort is necessary given the difficult task of being able to describe both deep core level excitations and low energy excitations, with finite momentum transfer, which can both give signatures of the many body physics in the system. The project is mainly devoted to the improvement in the description of RIXS, in particular in the extension of the first (ab-initio) attempts done recently by collaborators of the host group to the complicated case of indirect RIXS. On the side, the candidate aims at making her previous work on RPES available to the vast community working in photoemission, creating an interface with a well established and well structured tool widely used for interpreting X-ray results. The impact of the outcomes of such proposal are huge: it will connect theoretical communities working i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Platform for the implementation of a future inland navigation action programme' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

PLATINA3 provides targeted coordination and support activities to promote Inland Waterways Transport (IWT) in Europe. PLATINA3 makes the bridge towards future research, innovation and implementation needs within IWT in Europe. A key objective is providing the knowledge base for the implementation of the EU Green Deal in view of further development of EC`s IWT action programme (NAIADES) towards 2030. PLATINA3 addresses priority topics for the success of IWT: 1) integration & digitalisation of IWT in view of modal shift & synchromodality 2) zero- emission, automated & climate resilient fleet 3) skilled workforce anticipating to zero-emission & automation 4) smart & climate resilient waterway and port infrastructure with clean energy hubs. PLATINA3 is structured around fields Market, Fleet, Jobs & Skills, Infrastructure.Key experts and stakeholders are consortium partners ensuring required expertise and support: IWT sector and shippers (IWT Platform, BLN, ESC), member states and river commissions (CCNR, DC), waterway administrations (INE, viadonau), education institutes (STC, MAH), Waterborne TP / Sea Europe, workers (ETF), expertise centres (PDM and SPB/EICB). PLATINA3 sets up a coordinated platform consisting of these consortium partners enriched with committed Advisory Board members, policy makers, researchers, wider logistics and waterborne industries, other sectors and other transport modes. The platform is a catalyst for awareness, stakeholder engagement and uptake of outcomes from related national and European projects and initiatives. PLATINA3 consolidates their findings, assesses their impacts and gaps. Desk research and dialogues with experts and stakeholders lead subsequently to policy and R&D roadmaps and implementation plans. Interactive workshops and consulta