RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'THE PLANT’S INTERNAL CELLULAR SENSING AND RESPONSE MEASURES TO MECHANICAL BREACH' under Horizon Europe.

assistant: **Concept**

Plant-parasitic nematodes are microscopic organisms with exceptionally broad host range that pose major challenge to global agriculture, generate a predicted loss of 12.3 percent, equivalent to $157 billion each year. The losses caused by nematodes are further enhanced when they form disease-complexes with other microbes. Endoparasitic cyst nematodes are one of two most devastating groups, infecting the roots of economically important plants. The nematodes are a persistent problem because they have evolved an ability to secrete specific proteins to exploit the host plants development and suppress defense responses triggered by the plant. They begin feeding only after developing a specialized feeding structure (syncytium) inside the host root, by selecting a single cell near the innermost nutrient-rich vascular tissues, causing cellular injury by passing through multiple layers of different cell files. The majority of previous research has been on syncytium formation as infection proceeds. However, it is unknown how plants respond at the cellular level to the mechanical damage caused by nematodes, which prevents the creation of resistant plants to minimize crop losses. In the proposed study, cells from two internal consecutive cell layers surrounding the vascular tissues will be studied for their molecular responses to mechanical injury.  The control of lignin and suberin production, which function as physical barriers against invading pathogens, will be studied in particular. Advanced microscopic technology will be utilized to accurately produce mechanical damage in selected internal root cells using a cutting-edge method called laser ablation. It will offer a strong platform for the creation of resistance agricultural plants against plant parasitic nematodes in the lon
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Mentoring of IST-multipliers in associate candidate countries - extension'.

assistant: **Objectives**

Continuing their actions in the IST-Mentor and TRISTAN East projects, while exploiting the methodologies developed therein, the experienced EU multipliers, with the help of the local NCPs for IST, will identify candidate IST multipliers in 6 ACCs - EE, LT, LV, MT, PL, TR - and mentor them. These multipliers will be coached to extend the services of the NCPs for IST in the respective ACCs.Each ED partner will establish a liaison with one or more local candidate partners, in one or two of the participating ACCs, offering continued bilateral tutoring and support, in collaboration with the local NCPs. The IST multipliers from the ACCs will attend mentoring workshops, exposing them to FP6 and its instruments and to the IST WP. Each couple, formed of an EU partner and one or more multipliers, will thereafter engage in a bilateral action, in which the former will transfer knowledge and hands-on experience to the latter, who will be coached in the requirements and rulings of FP6.This will facilitate the assistance of the multipliers to local IST enterprises - and to ACC entities wishing to adopt IST - to participate and respond to Calls for Proposals within the IST Priority, and will augment the proportion of ACC entities in EC funded IST projects.The Consortium will assist the IST multipliers (bilaterally and jointly) in:a. organising local mailing and phoning awareness-building campaigns (aimed at identifying potential IST developing or IST utilising entities that could benefit of FP6 projects),b. organising awareness building and dissemination Seminars and Workshops,c. joining a network of IST-multipliers created in the other ACCs and NIS (In IST-Mentor and TRISTAN-East, and assisting ACC entities to build or join STREP, IP or NoE proposals, together with EU partners.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Endoscopic Multi-Spectral Optoacoustic Tomography' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The ERC-MSOT (233161) proposal developed a new imaging modality, termed Multi-Spectral Opto-acoustic Tomography, applied to mesoscopic biological imaging of small animals. MSOT breaks through the penetration limit of optical microscopy and can image several millimeters of tissues in-vivo at high resolution. This performance has recently attracted the interestof clinicians, in particular for the clinical application of the technology to address limitations of current endoscopic methods imaging the gastrointestinal (GI) tract. With millions of gastrointestinal endoscopies performed each year and a rising number of procedures due to colon screening programs established worldwide, advanced methods for endoscopic imaging appear preliminary as a viable commercialization opportunity. This ERC PoC proposal will therefore establish a proof of concept for the development and application strategy of endoscopic MSOT (EMSOT).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Equine Polyclonal antibodies Immunotherapy against COVID-19/SARS-CoV2–VOC', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The highly contagious SARS-CoV-2 virus has generated an unprecedented pandemic with global dramatic public health and socio-economic consequences need an urgent mitigation. Despite the progression of the global use of efficient vaccines, an increased transmissibility of variants of concern (VOC) is predominantly observed. The reduced sensitivity of VOCs to neutralizing response could become a serious obstacle for efficient vaccination. In the absence of approved specific antiviral therapies for vaccinated-non-responders and the scarce anti-inflammatory therapies, passive immunotherapies with polyclonal immunoglobulins could be considered a part of the solution. The main objective of EPIC-CROWN is to rapidly assess, in multicentric clinical trials (phase IIa, 16 patients and IIb, 400 patients), an EMA-authorized antiviral immunotherapy based on potent and broad equine neutralizing anti-SARS-CoV-2 polyclonal F(ab’)2 antibodies in COVID-19 patients, including VOC carriers. In order to save lives and reduce the use and costs of critical care, this therapeutic solution expect to reduce at least by 50% ICUs admissions and a highly significant mortality rate of treated patients. To optimize the indications for the treatment, potency and breath of F(ab’)2 against variants will be assessed in in vitro and in an animal model as well as prospective studies will respectively be done on immune assessment in treated patients and on mitigation of exacerbated immune responses in vivo.Fab’entech will coordinate EPIC-CROWN-2 formed by outstanding experts in different project domains that include clinical trials (HISS, Greece), virology (IMAS12, Spain), and immunopathology models and mitigation (BNITM, Germany - IRD, France). Most of them having already been working together in European p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Fiction, science and science fiction. the role of literature in public debates on medical ethical issues and in the medical education.' (1998-2002).

assistant: **Concept**

Novels have deeply influenced their readers in thinking about all kinds of ethical dilemmas regarding health care, illness and the physician-patient relationship. The hypothesis underlying this proposal is that fiction (e.g. novels, film) has an important role to play in professional reflection and public debate on ethical problems in health care. Little systematic research into the role of fiction has been done in the EC so far. A multidisciplinary approach will lead to valuable results and, additionally, to an interesting network within the EC that can stimulate this important way of looking at medical ethical problems.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Nanostructured Lithium Conducting Materials' to be submitted under Seventh Framework.

assistant: **Abstract**

Solid State Ionics, as an interdisciplinary science, covers chemistry, physics and materials science. The applied perspectives, that include high-energy-density batteries, fuel cells, electrolysis cells, chemical sensors, electrochromic devices and solar cells, and the need for their improvements are an important catalyst for designing new materials. Besides these attractive applications, academic research needs to be reinforced since ion transport in disordered materials is still poorly understood. In particular, the study of nanomaterials opens new questions related to the relationship between structure, processing and physical properties.The aim of this exchange program lies on the investigation of (i) the grain size effect and (ii) the crystallinity on ionic transport of Li-conducting materials based on perovskites, compounds with Nasicon structure and LiPON. Amorphous, nanocrystalline and microcrystalline oxides and oxynitride will be synthesized as powders and films. Processing of these materials and sintering will be performed to obtain thick films and high density pellets. Influence of micro and nanostructure on Li mobility will be investigated. TEM, SEM could offer a wealth of information on nanostructured compounds. Systematic investigations performed on these materials, using different dynamic techniques, able to probe static and dynamic properties at the microscopic level, will be useful, i.e. Nuclear Magnetic Resonance on 6Li and 7Li nuclei (with their different techniques: static NMR, MAS-NMR, 2D NMR, Pulse Field Gradient), quasi-elastic neutron scattering, broadband impedance and dielectric spectroscopy. In particular, the relationship between structure and physical properties will be clarified to lead to a rational design of ionic conductors and to an im
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Molecular mechanisms underlying chemotherapy resistance, therapeutic escape, efficacy and toxicity' under Sixth Framework.

assistant: **Concept**

The overall aim of the proposed project is to improve the outcome of cancer chemotherapy by developing novel tools to predict tumour response to treatment as well as individual toxicity to chemotherapy. The projectwill seek to identify and validate mechanisms of intrinsic and acquired chemotherapy resistance, as well as predictors of efficacy and of individual toxicity. This is achieved by integrating the work of groups conducting large clinical trials with preclinical research groups, as well as with state of the art-platforms for genomic and proteomic analyses and bioinformatics.The participants have chosen to focus on melanoma and lung cancer as model tumours of separate histogenetic types exhibiting intrinsic resistance and/or a high degree of acquired resistance to chemotherapy. Candidate mechanisms of drug resistance and therapeutic efficacy will be identified using genomic and proteomic analyses of sequential tumour samples and paired sera obtained before and after chemotherapy as well as experimental systems, including in vitro studies of tumour cell lines, transplanted human tumours and novel animal tumour models,. These putative mechanisms will then be validated in further analyses of larger sets of tumour biopsies from patients. Functional studies of novel mechanisms and pathways will be also performed using in-vitro systems and animal models.The result of these activities will thus be a set of clinically and functionally validated mechanisms of chemotherapy resistance and therapeutic efficacy. Likewise, large scale genomic analyses of patients receiving chemotherapy as part of clinical trials will be performed in order to validate novel markers of individual toxicity following chemotherapy.The novel knowledge obtained through the project will lead to new too
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Imaging and multimodal monitoring in clinical diagnosis of neurological disorders' (1998-2002), addressing dissemination and exploitation.

assistant: **Impact**

- Acquire hands-on experience in image processing (combination of CT, MRI and SPECT) for quantitative assessment of neurological disorders. - Provide methods to combine the results of image analysis with information obtained through multimodal brain monitoring to enable comparative analysis of the quantitative yield of each technique versus cost and risk to the patient. - On this basis, in one of the selected application fields (degenerative motor disturbance, hydrocephalus and brain injury) to indicate the most effective selection of clinical methods for acute assessment and subsequent clinical follow-up.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Natural variability of a coastal upwelling system and small pelagic fish stocks' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

NAT-FISH will analyse and quantify the influence of the natural variability of the Northwest African up welling system on the abundance and distribution of small pelagic fish stocks. It aims at creating an information system, which incorporates environmental monitoring into predictive analysis of the status of fish resources for early inclusion in responsible fisheries management. The project is carried out as a retrospective analysis of environmental data, satellite data and fisheries data. Physical and biological models play significant role in the project. The project is undertaken by the institutions responsible for providing advice on fisheries management in their home countries, assuring that the activities of the project are relevant for institutional tasks related to fisheries management.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Control over interfaces in metal oxide optical coatings:  the missing piece of the puzzle' under Horizon Europe.

assistant: **Concept**

Multilayer thin-film coatings grant optical elements their specific functionality by forming a high-reflective mirror or a dichroic filter. At the same time, the coatings are the first instance to be damaged by intense laser light, corrosion, or mechanical stress. Limited coating durability is heavily influenced by interfaces: the coating – substrate interface and interfaces between layers. Despite a thorough understanding of the properties of the layers’ bulk, control over interfaces is still highly limited. The lack of convenient methods for their characterization makes facilities rely on empirical tricks, thus compromising interface quality and posing severe limitations on the cutting-edge applications of optics. The COINED project aims to break this barrier by introducing an optical interface characterization with nanometer longitudinal resolution. Such resolution will be enabled by using a structured laser pulse as a source of complex acoustic waves in the coating. The same structured pulse will be used to induce second-harmonic generation (SHG) locally enhanced by the acoustic wave. By using a large set of complex pulses, we will be able to decipher the nonlinear response and the related interface morphology in individual interfaces of multilayer coatings.With this unprecedented control over interfaces, the project will disclose the role of deposition processes, coating post-treatment, and aging in the formation of unintended interlayers, defects, or coating restructuring. Moreover, the ability to continuously monitor and map interfaces throughout coating tests will be the game-changing factor elucidating the processes behind interface deficiencies.Interface optimization will open new horizons in the development of space-grade optics, increasing feasible laser pow
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'NEutral Data host for UNcrewed Avitation' under Horizon Europe.

assistant: **Concept**

NEDUNA provides holistic and dynamic data about airspace connectivity and ground risk for uncrewed/unmanned aviation.  This is a must have requirement to enable automated BVLOS (beyond-visual-line-of-sight) drone operations and hence for the drone business at scale.Drones will revolutionize a wide range of industry verticals, including all kinds of automated inspections, first responder services, agricultural services, delivery & logistics operations, media & entertainment, all the way to drone taxis!  A market that is expected to exceed €100bn in annual revenue in 2028.But in order to make that a reality at scale, unrestricted and automated BVLOS drone operations are needed, which is not the case today.However, to make automate BVLOS drone operations at scale a reality, it is a critical regulatory requirement to have evidence of safety critical data: a) Where in the airspace there is sufficient connectivity to safely operate a drone (which is a must have requirement for remotely controlled aircraft) and b) have a holistic understanding about the ground risk, i.e., how many people are on the ground along a flight path.This is where NEDUNA comes in.  It provides all the needed information in an aggregated manner, through a single interface, from a single location, via a single contract.  This is the reason why key stakeholders in the value chain are expressing high interest and have already provided their Letters of Interest, including: EASA, Civil Aviation Authorities (such as AustroControl), ANSPs and Approval Authorities (such as AVINOR), ATM/UTM system providers (such as FREQUENTIS), Drone Operators (such as SmartDigital) and telecom providers (such as T-Mobile).  NEDUNA is to airspace connectivity data what iTunes is to the digital music industry.Hence, NEDUNA is a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Intelligent decision from vineyard robots' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The wine industry is strategically for Europe, both economically and socially speaking. Its competitive position in the global market depends on the long-term reputation of its wines, which needs many years to be built but can be lost quickly with a poor wine. The risk of losing reputation is high when repeatability cannot be granted, which happens ever more in the vineyards where manual data sampling is meager due to unaffordable costs.Therefore, our aim is to industrialize, demonstrate, and take as first ones to market an innovative expert field monitoring system (decision support system) embedded in a small-size and cost-efficient robot for the vineyard, which will be the follow-up of the successful EU-funded project VineRobot (TRL6/7).  In order to ensure commercial success, we will optimize both the external design and the internal electronics, as well as industrialize the navigation and mapping software for top performance, protection, and user friendliness. For this we count on an industry-driven consortium, targeting one of the largest agricultural sectors in Europe, with a strong business plan and the support of a large number of committed industry leaders and end-users, ensuring a rapid market deployment. Market penetration will be boosted by the SMEs already active in the robotics and viticulture sectors, reinforced by strategic tradeshows and international conferences.As a result, we target a cumulative turnover of €33 Million in five years yielding €10.9 Million of industrial benefits, reaching a market adoption of 5% which will provide service to 54,540 ha of EU vineyard area. In addition, VineScout technology will attract young farmers to rural areas, which is becoming crucial for the sustainability of the sector since current farming population is near r