RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project '5G Mobile Network Architecture for diverse services, use cases, and applications in 5G and beyond' (5G-MoNArch) under Horizon 2020.

assistant: **Objectives**

Motivation: The expected diversity of services and use cases in 5G requires a flexible, adaptable, and programmable architecture. While the design of such an architecture has been addressed by 5G-PPP Phase 1 at a conceptual level, it must be brought into practice in Phase 2. To this end, 5G-MoNArch will (i) evolve 5G-PPP Phase 1 concepts to a fully-fledged architecture, (ii) develop prototype implementations and (iii) apply these prototypes to representative use cases.Approach: 5G-MoNArch architecture design will combine Phase 1 concepts (such as virtualisation, slicing and orchestration of access and core functions) with three enabling innovations that fill gaps not ad-dressed in Phase 1: (i) inter-slice control and cross-domain management, to enable the coordination across slices and domains, (ii) experiment-driven optimization, to leverage experimental results to design highly performing algorithms, and (iii) cloud-enabled protocol stack, to gain flexibility in the orchestration of virtualised functions.Testbeds: The devised architecture will be deployed in two testbeds: (i) the sea port, representative of a vertical industry use case, and (ii) the touristic city, representative of a mobile operator deployment. For each testbed, 5G-MoNArch will instantiate the architecture and complement it with a use case specific functionality – the two functional innovations of 5G-MoNArch: (i) resilience and security, needed to meet the sea port requirements, and (ii) resource elasticity, to make an efficient use of the resources in the touristic city. Impact: 5G-MoNArch has a very high potential for commercial impact, including enhanced products (e.g., orchestrators or edge-cloud RAN), novel services (enabled by network slicing) and opportunities for new market players. To exploi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Fostering European cellular Agriculture for Sustainable Transition Solutions' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The current food system is insufficient and unsustainable, generating 17% of the total GHG emissions for animal farming while only supplying 18% of the global calories and 37% of the global proteins. The cultured meat (CM) and cultured seafood (CSF) industry is emerging to meet the growing demand of protein with promises of lower environmental footprint. However, the current knowledge on the impact of this sector is limited, based on developments that have not happened yet and lacking important considerations such as its social impact or its adaptability to current and future demand. Current race-to-market pressures, fueled by recent market approvals overseas, highlight the need to define a roadmap that can develop the sector in an ethical, sustainable and cost-competitive way. This is a unique opportunity for an effective reorganisation of the food system to establish resilient value chains in the EU. Gathering a large set of independent food system actors, FEASTS will provide an unprecedented, unbiased and robust knowledge base for the assessment of the sustainability aspects of the CM/CSF sector by actively promoting multistakeholder engagement and co-creation activities grounded on transparent dialogue and open science practices. It will explore different production methods, product types, supply and value chains as well as business models to provide balanced solutions that are not only sustainable by design and cost-efficient, but also ethically responsible, safe and nutritious, fair and inclusive. FEASTS, designed as a think-tank, adopts a Food Systems Thinking approach and a multidimensional impact assessment including not only LCA, TEA and SLCA of CM/CSF products and their comparison to conventional counterparts but also systems dynamic modelling and integrated
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The molecular basis of Cockayne Syndrome' under Seventh Framework.

assistant: **Concept**

Cockayne syndrome is a congenital disease with impaired DNA repair in actively transcribed genes. Affected children show developmental abnormalities and signs of premature aging. Cockayne syndrome is caused by mutations in the Cockayne syndrome complementation group A (CSA) and B (CSB) genes. While CSB encodes a SWI/SNF ATPase that likely assists the stalled RNA polymerase in overcoming lesions, CSA’s detailed role in repair has so far remained elusive. CSA is part of the DDB1-CSA-Cul4-Rbx1 E3 ubiquitin ligase complex. The available data suggest that CSA may function as a substrate adaptor for ubiquitination by the DDB1-Cul4-Rbx1 ligase.I will pursue a novel structure-driven proteomic approach to identify the substrate epitope recognized by the DDB1-CSA-Cul4-Rbx1 E3 ubiquitin ligase. These experiments aim to provide the important missing signal required for recruitment of the ligase complex to sites of stalled RNA polII complexes. Importantly, the CSA ligase, as it arrives at sites of DNA damage, is inactive. Our comprehensive structural and biochemical efforts will thus include the mechanisms of regulation of the CSA ubiquitin ligase activity by activators and inhibitors following recruitment to the repair site.MoBa-CS will not only improve our understanding of CSA’s molecular role in Cockayne syndrome, but also reveal CSA’s mode of action within the essential transcription coupled repair pathway. Understanding the cellular signals overseeing transcription coupled repair will provide important insights into how the pathway is integrated within the overall DNA damage response circuitry of the cell. ERC funding would enable us to pursue an interdisciplinary proteomic and structure based approach in examining DDB1-CSA function.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Enlargement: building linkages on prospective activities' (1998-2002).

assistant: **Concept**

Specific Objectives- Strengthening the network of Foresight institutions in Enlargement Countries and link it up with similar EU wide network.- Increase the mobility (and training) of Foresight experts from candidate countries;- Performing studies of specific challenges relating to socio-economic, political and technological development issues and its impact on S&T policy;- Prepare jointly with project 69 (the Futures Project) a new long term 2020 project which would include Enlargement countries.Planned Deliverables- The diffusion and communication of the results of the Enlargement Futures Project. The Unit members will organise and participate in seminars and workshops in Candidate Countries, EP and EC services to diffuse the findings of the projects. This action should try to achieve a level of awareness of policy makers similar to the one achieved by the Futures project;- Second phase of the Enlargement Futures Project. In depth study of two or three challenges identified at the Bled Forum (to take place in December 2001). Candidate issues for this challenges are: Enlargement and the Information Society (in joint venture with the e-Europe initiative of DG INFSO), Science and Society (to be developed jointly with DG RTD). Both activities will be of a horizontal nature and thus be developed together with other IPTS Units;- Preparation of a new Futures Project: Futures 2020. Start the preparatory work for a new IPTS wide foresight initiative on the challenges and shape of the EU after the current Enlargement (EU28+). IPTS wide activity with a major contribution from Enlargement countries.Specific deliverables to DGs:Presentations to different Services of the results of the Enlargement Futures project on the following issues:- Economic transformation in PACs;- Knowledge
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'ERA Chair for Food (By-) Products Valorisation Technologies of the Estonian University of Life Sciences' (By-) targeting Horizon 2020.

assistant: **Abstract**

Advanced food processing technologies, minimum waste and maximum utilisation of raw material used as well as valorisation of by-products constitute a highly relevant range of topics in the EU and worldwide. These are matters that the University of Life Sciences (Eesti Maaülikool, EMU) has been dealing with for long from various angles and perspectives. However, to realise the full potential of EMU in this domain, structural changes are needed to bring various related competences under a unified umbrella as well as to cover several gaps hindering further development. Therefore, the main objective of the current project is to establish a new ERA Chair for Food (By-) Products Valorisation Technologies (VALORTECH), and recruit a top level researcher/research manager (ERA Chair holder) to lead this interdisciplinary, inter-unit entity, formed based on a joint effort by the Institute of Agricultural and Environmental Sciences and the Institute of Veterinary Medicine and Animal Sciences of EMU. The new Chair is expected to considerably improve the research and innovation performance of EMU and conduct forefront research that would create significant benefits for both Estonia, Europe and beyond.Efficient dissemination and exploitation of research results is an issue of key importance in the context of the ERA Chair´s action plan. In addition to targeting the international research community and providing input to policy development, facilitating knowledge transfer to industry is at particular focus. The R&D to be carried out in the VALORTECH Chair is strongly connected with both the national and regional Smart Specialisation strategy, in the context of which efficient use of resources and related development of health-promoting (functional) food are among key priorities. The de
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Euroscience Open Forum (ESOF) in Munich, 2006' under Sixth Framework.

assistant: **Concept**

Euroscience Open Forum (ESOF) in Munich, 2006 ESOF will be a pan-European Forum on all sciences, including engineering, social sciences and the humanities, to be held in Munich July 15th to 19th 2006. The general purpose of the Forum is to showcase European science and to enhance dialogue between science and society. ESOF2006 will be the second event of its kind. The target is to attract about 2200 participants, including researchers, political decision makers, journalists, and lay persons interested in science and technology. In attracting such diverse target groups ESOF2006 will encourage exchange between different scientific disciplines, cultures as well as between the professional and public sphere through enhancing the public's interest in science and shaping the scientists' awareness of the public's rightful role. ESOF2006 will also be a platform to address the important themes of science governance, such as ERA, thereby creating a more dynamic interface between science and policy making. Thus, it encourages the active participation of scientists in policy development and contributes to shape the European scientific culture. The event will be combined with an extensive outreach programme which takes place in the heart of Munich as to ensure a high recognition by the Munich public. Interactive exhibitions, talks and presentations will invite participants from all age groups to get a hands-on experience of research as well as encourage them to join in critical discussions on issues related to modern science. Following the sucess of the first Forum, ESOF2006 will further pursue the goal of inspiring young people to consider careers in science. Therefore, a special career programmes is organised to present particular career opprtunities and challenges of the new scien
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Precision Nutrition to optimize immune response for metabolic health', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

NUTRIMMUNE examines how dietary factors affect immune responses across varying degrees of obesity-related Noncommunicable Disease (NCD) severity. This focus is crucial given obesitys link to NCDs and infection risks. The project gathers 6 academic groups and 1 SME across 4 European countries over 4 years and a 4.3M grant to evaluate the interplay between nutrition, glycome, microbiome, and immune health in obesity and immune impairment.NUTRIMMUNE leverages partners: i) Access to European databases and biobanks, enabling in-depth analysis at cellular and molecular levels, ii) Proficiency in conducting dietary intervention studies in human subjects, and iii) Experience in mechanistic and functional diet-glycome-microbiome interactions.In WP1, the project deciphers phenotypic, multi-omics, and dietary factors responsible for variability in Immune Checkpoint (ICP) expression and immune impairment in existing cohorts. WP2 focuses on a 24-week precision nutritional intervention to assess the potential of a pro-immune diet to restore T cell fitness in obese subjects. WP3 conducts comprehensive profiling before and after the dietary intervention, examining innate and adaptive responses, cytokine patterns, alongside ICP labeling. WP4 provides mechanistic aspects on how the diet, glycome, microbiome influence immune health. WP5 employs machine learning models to identify predictive markers and signatures for ICP expression and altered immunity, to identify dietary patterns and food affecting immune function. WP6 ensures efficient project management and effective coordination, ethics compliance, dissemination, and exploitation. WP7 explores synergies with portfolio projects for challenge goals.The projects goal is to move from our novel idea that precision nutrition influences imm
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Multiscale modeling and simulation of bacterial colonies' (2007-2013) targeting Seventh Framework.

assistant: **Abstract**

Some bacteria are known to grow in colonies that form complicated geometrical patterns. In order to develop such a colony, bacteria will sense and respond to their local environment by secreting and absorbing peptides, proteins, pheromones and other chemotactic or quorum sensing molecules. Furthermore, under adverse conditions, bacteria can sporulate, alternate its shape, or look for better DNA. Past work has focused mainly on the biological aspects involved in these processes. However, much less is known on the dynamics of the colony as a whole. In particular, the dynamics of the colony may be completely different than that of the single cell and it is not clear how the bacterial activity at the microscopic scale is related to the collective macroscopic behavior. A recent mathematical model that I developed explains an interesting experiment in which sibling bacterial colonies grown on low-nutrients plates mutually kill each other through secretions released to the media. Simulation results where compared with experimental data. The work was recently submitted to PNAS. The purpose of the proposed research is to develop new and improved models and innovative simulation methods for connecting between the microscopic behavior of individual bacteria and that of the colony as a whole. New algorithms are developed in order to solve the models numerically. Such an interdisciplinary research is crucial for understanding complex biological phenomena. There are many interesting and important directions for future research. For example, new experiments suggest that surface tension may play a key role in the dynamics of the colony. Another example is the addition of newly discovered knowledge on the mechanism bacteria use to decide between sporulation (going into a dormant phase)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Sources, Interaction with Matter, Detection and Analysis of Low Energy Electrons 2' (SIMDALEE2).

assistant: **Innovation**

The purpose of the SIMDALEE2 (Sources, Interaction with Matter, Detection and Analysis of Low Energy Electrons) network is to establish a world-class research training platform for the science and technology of nanoscale manipulation and analysis using low energy electrons. Apart from an effective and  well-structured training programme, the network will pursue the following scientific goals: (1) optimizing  beam size by correlating contemporary field emission (FE) theory with high resolution holographic measurements of magnetic and electric fields of FE tips with different shapes, both with and without primary electron optics; (2) putting the understanding of the contrast mechanism of electron beam techniques on a sound footing by comparing physical models with novel benchmark spectra acquired using a coincidence technique; (3) improving detection as well as understanding of emitted energy-, angular-, and spin-dependent spectra. This issue will be addressed for the common case of detectors in the a field-free environment, and for the special case when the emitted electrons encounter an electric field prior to detection; (4) Electron beam modification of nanostructured surfaces; (5) Progress in the aforementioned fields will lead to the development of an innovative prototypical methodology for nanoscale characterization with electron beams in the form of a compact desktop-type Near-Field-Emission Scanning Electron Microscope (NFESEM). Finally,  (6)  the economic impact and feasibility of low energy electron beam methodology will be investigated within the project. Accordingly, the ESRs and ERs will develop and acquire experience on a comprehensive methodology beneficial for any industrial or academic laboratory employing or developing electron beam techniques for natura
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'An innovative technology, based on UV radiation, to strongly reduce the microbial activity of the air inside the store rooms of cultural heritage conservation institutes' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

An innovative technology, based on UV radiation, will be developed to strongly reduce the microbial activity of the air inside the store rooms of public and private museums, archives and libraries where the cultural heritage's collections are conserved. The direct irradiation of objects and the formation of ozone by the UV light will be respectively prevented through the development of proper shielding and catalysts of manganese oxides supported by honeycomb graphite structures. The adoption of the proposed equipment will strongly reduce the biologic activity of the particles suspended in the air and minimise the spread of fungal infections that are responsible for irreversible deterioration of priceless objects and dangerous for the health of people working in the institutes.The successful completion of the project will put at disposal to thousands of European museums, archives and libraries a new kind of equipment that will minimise the need of the traditional fumigation with toxic gases, such as Ethylene Oxide, that are currently carried out to disinfect the store rooms. The proposed research accomplishes the CAFE initiative (Clean Air for Europe) of the Commission, a daughter directive of Air Quality for Europe Directive that explicitly mentions the need of decreasing any activity related to cultural heritage that would lead to air pollution. The project is also coherent to the Community interventions through the Culture 2000" framework programme and Structural Funds."