RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Rugged  Long-lasting Vertical-Axis Wind Turbine for Extreme Wind Conditions' (NJORD), addressing dissemination and exploitation.

assistant: **Impact**

Extreme weather conditions (i.e. strong and unsteady winds, icing, etc.) - that countries such as Iceland and the other four Nordics (Sweden, Denmark, Norway, and Finland), the UK, Ireland, Canada´s Prairies, Northern US, Russia, and Nigeria along with high altitude sites face - make traditional wind turbines (horizontal-axis) to spin out of control resulting in catastrophic system failure in the first year of operation. As a result, these locations needed a different kind of wind technology capable of working over a wide production range (whether it’s in the stormy afternoon, in hurricanes or on calm and icy winter nights in the range of -10 to -30 °C) with virtually no need of maintenance. Thus, IceWind has created a rugged, standalone, and cost-effective vertical-axis wind turbine (VAWT) of unique and fabulous blade design, great durability and nearly maintenance-free for off-grid applications that require a continuous (no cut-outs) source of power (electricity and heating). The excellent match of aerodynamics and materials give our NJORD turbines unique features such as optimal structural stability, strength, and hence durability to withstand the most extreme wind conditions. Our VAWT can produce electricity at very low wind speeds as well as for high speed of strong winds spinning elegantly, non-stop, and noiseless. As for our commercial strategy, we plan to respond: 1) directly to individual end-users of isolated areas for residential applications (i.e. cabins, homes, and small farms) mainly in Iceland and other EU countries (i.e. the other four Nordics, the UK, Ireland, etc.), 2) telecommunication operators for telecom towers worldwide, and 3) developing countries such as Nigeria, all demanding a reliable and sustainable source of power generation. Expected profi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Risk-based detection and protective filtration system for airports against airborne chemical, biological or radiological hazards' (AIRSECURE) targeting Sixth Framework.

assistant: **Abstract**

The fear of terrorist attacks against civil targets has increased recently. One of the most frightful scenarios is the use of airborne chemical, biological or radiological (CBR) weapons against unprotected civilians. Of particular concern are airports where such an attack may cause extensive injury and severe impact on the aviation industry and the whole economy of the European Union. High efficiency filtration is one of the few measures that can be implemented in advance to reduce the consequences of intentional CBR agent release. However, due to the high pressure drop, large space requirements and the high initial and operating costs the present high efficiency filters are not practical solutions for existing buildings. Moreover, their installation would need costly and time-consuming renovation of the whole ventilation system. The AIRSECURE system will improve the security of passengers and workers at airports by a comprehensive approach including risk analysis for identifying the high-risk areas, novel protective filtration systems, proper air distribution, and detectors for early warnings of threat.The main idea of the AIRSECURE solution is to combine promising new filtration technologies for removal of both particulate and gaseous hazardous agents with a protective filtration unit. These distributed units can be flexibly and quickly installed in the supply air of the high-risk areas. The very low flow resistance of the filter allows its installation without extensive modifications to the ventilation systems. New particle detectors will be developed to monitor the performance of the filtration system for maximum security. The optimum number and location of both particle and gas detectors and protective filtration systems are based on risk analysis. The secure air-f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Identifying and understanding the cis-regulatory modules that control the spatio-temporal transcription of genes in chordates' (CISREGLOGIC).

assistant: **Innovation**

A major challenge in deciphering the genome is to understand the genomic sequences which control the spatio-temporal expression of genes. Despite much progress, the rules by which these regions, the cis-regulatory modules (CRMs), control the transcription of a gene remain unclear. The objectives of this proposal are to develop an algorithm to detect novel CRMs, to analyze the identified CRMs, and to elucidate the logic by which CRMs control when a gene is transcribed and in what cells. This will be done by first developing an algorithm that integrates several recent breakthroughs in understanding CRM mechanisms and using a mid-throughput chordate model organism (Ciona intestinalis) for validation. Recent work has shown that many factors contribute to CRM activation in addition to the well-known clustering of transcription factor binding sites: the openness of the chromatin, 3D structure of the DNA, nucleosome positioning, and co-factor binding. Combining this understanding with previous prediction methods (evolutionary sequence conservation, binding-site clustering) will improve predictive power, which I will experimentally confirm. The CRMs will be refined to their essential sequences by comparing them to their orthologs in distant species that drive similar expression patterns. The identified CRMs will be used in a second step to analyze and classify the CRMs. Finally, combining the identified CRMs with known patterns of expression will provide a means to elucidate the rules by which CRMs operate. This work will impact fundamental biology and also contribute to identifying and understanding mutations with disease implications, as SNPs within a CRM have been shown to have effects in genetic diseases, such as cancer.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Atomistic spin dynamics and spectroscopic investigation of spin-induced magnetoelectric multiferroic materials' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Magnetoelectric (ME) multiferroics (MFs), materials that can combine ferromagnetism and ferroelectricity, are strong candidates for a wide range of novel hybrid technological applications, such as sensing, energy harvesting, data storage, magnonics, and spintronics, to name a few. Most importantly, the ability to manipulate the magnetization by electric fields leads to simple, cost-effective and energetically sustainable technological strategies. Despite the great efforts of the MF scientific community, the origin of the ME coupling in a series of MF materials still remains ambiguous. Experimental findings may frequently be inconclusive and misinterpreted; therefore a solid theoretical approach is essential for developing further insights in the fundamental physics hidden behind magnetoelectricity.Ni3TeO6 champions both the static and dynamical ME effects among the single-phase MFs. In pursuit of new spin-induced MFs, resembling the celebrated Ni3TeO6, we propose the investigation of a series of compounds of the form M3TeO6 (M=Ni, Mn, Co), with a combination of mixed-valence transition metal anions on the M-site, by employing a combination of first principles calculations of spin dynamics together with experimental spectroscopic investigation. The researcher has experience in spectroscopic techniques for ME MFs, background in first principles calculations, and aims at training in the field of first principles calculations for spin dynamics. The supervisor Prof. Sanvito is an expert in ab initio predictions with atomistic spin dynamics.EMAGICS’ target is to unveil the underlying mechanisms that lead to the enhancement of the ME MF properties, as well as possibly increase the critical temperatures in favour of the applications. Thereafter, EMAGICS will be able to propose
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'SmartGrid Distributed Monitoring, Synchronization and Active Management' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

A critical challenge for smart grid ecosystems is to optimise the ROI for Utilities.  SmartGridEnable will addresses this by creating product solutions to help Power Utility Distribution Network Operators (DNOs) achieve their carbon reduction targets by enabling them to better manage their network in support of lower carbon footprint technologies & new energy generation business models from green energy renewable sources. Using patented current/voltage sensing technology MAC has identified two business opportunities that will greatly assist DNOs in the management of their Low Voltage (LV)  & Medium Voltage (MV) Distribution networks. These include; (a) the development of a LV Network Monitoring System to support Demand Response Management Systems (DRMS). This solution will directly feed into & support DRMS currently being put in place by all DNOs for better network management of lower carbon footprint technologies, such as e-cars & renewable energy generation on their networks.  (b) development of a cost effective Phasor Measurement Unit (PMU) for mass deployment, that will help DNOs avoid grid instabilities,  & monitor generators’ response to abnormal deviations in system frequency due to load variations  & renewable energy connections.Mass deployment will also enable DNOs facilitate lower tariff offers on renewable energy generation to customers when peak supplies such as wind is available, thus reducing existing power plant outputs. The solution will assist European DNOs achieve their 2020 carbon reduction targets & be carbon neutral by 2050, reducing networks outages duration  & customer losses by 20%, & improving overall management of the distribution grid by 15%.SmartGridEnable uses patented sensing technology that was developed for fault monitoring on MV neutral
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Science in the City' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

‘Science in the city’ will be the motto to involve the general public with research activities and scientific knowledge that are underway to help answering to major concerns of urban communities related to global changes, and to shape and improve quality of life for the next decades.  This motto is highlighted given the increasing levels of concern perceived in urban society, in particular among young people, on how to overcome global changes, while preserving natural and cultural heritage in the attempt to reach sustainability. By adopting this vision for the European Researchers' Night, this proposal intends to respond to Responsible Research and Innovation (RRI) and societal goals of the EU framework program. It aims therefore to raise public awareness on the relevance of science to assure quality of life in the future and to bridge the gap between scientists and society, giving researchers the opportunity to perceive the main concerns of citizens and how they see and understand their work, while engaging young people with science. The project will reflect on this problematic in the context of cultural heritage preservation.  The consortium of this project, coordinated by the University of Lisbon through the National Museum of Natural History and Science (MUHNAC-ULisboa), combines efforts between researchers of major universities in Portugal – University of Minho, University of Lisbon, Nova University in Lisbon, University of Évora and the Lisbon University Institute. The Higher Institute for Tourism and Hotel Studies in Estoril will contribute to the cultural heritage preservation approach while disseminating food security practices and the Lisbon municipality will be a central partner for the engagement of diverse audiences and civil society stakeholders. The proje
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Advanced Real-Time Systems' (ARTIST) under Fifth Framework.

assistant: **Objectives**

The aim of ARTIST is to co-ordinate the R&D effort in the area of Advanced Real-time Systems so as to: Improve awareness of academics and industry in the area, especially about existing innovative results and technologies, standards and regulations: Define innovative and relevant work directions, identify obstacles to scientific and technological progress and propose adequate strategies for circumventing them. ARTIST consists of three strongly concerted actions, respectively on <Hard Real-time systems>, on <Component based Design and Development> and on <Adaptive Real-time Systems for QoS Management>. The participants are 30 academic research teams from 22 European institutions with relevant contribution in the area. The Initiative has also associated industrial partners who manifested their interest and support and will contribute to the progress of the work.OBJECTIVESThe aim of the Initiative is to co-ordinate the R&D effort in the area of Advanced Real-time Systems so as to- Improve awareness of academics and industry in the area, especially about existing innovative results and technologies, standards and regulations- Define innovative and relevant work directions, identify obstacles to scientific and technological progress and propose adequate strategies for circumventing them.DESCRIPTION OF WORKThe Initiative will focus on three relevant work directions- Hard Real-Time Systems- Component based Design and Development- Adaptive Real-Time Systems for QoS Management. The work includes- Technical meetings with associated industrial partners- Dissemination of innovative results/technologies- International collaboration with outstanding US teams and important US R&D projects in the area.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'WI-CHARGE: THE FUTURE OF POWER'.

assistant: **Innovation**

Wi-Charge is developing a paradigm-shift in wireless power systems that overcomes current limitations, allowing charging devices over the air with a range of 10 meters and available power that is 100X more than batteries. All this preserving health and safety requirements. Our technology will enable the appearance of many new devices and functionalities that today are simply not possible. Imagine devices can enjoy 100X-500X more power than they have today and still work permanently in a wireless mode. It will enable a huge breakthrough in many industries and will take User Experience to the next level. Our goal is developing proprietary transmitters and receivers, designed to operate for the 1st time at a specialized Infrared (IR) spectrum that we found to be the best one to optimize power, distance, efficiency, and most important, safety; while providing more than 100X better performance compared to solutions based on magnetic induction, radiofrequency (RF) or ultrasound beaming.


**Keywords:** Wireless power,Infrared,Wireless charging,Long range wireless power
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Parallel epigenomic and apoptotic profiling to identify targetable sensitivities in Multiple Myeloma' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Multiple Myeloma (MM) is an incurable cancer caused by uncontrolled growth of the plasma cells. A major challenge is drug resistance, which is caused by increased reliance on the anti-apoptotic BCL-2 family proteins and altered epigenetic landscapes. Dependence is highly variable, with distinct dependencies on BCL-2 family members  (MCL-1, BCL-2 & BCL-XL) across patient samples. It is currently not understood what causes heterogeneity of BCL2 dependence in MM, and thus exploiting this reliance for treatment has proved difficult. Epigenetic modifiers regulate apoptotic pathways and therefore represent a therapeutic avenue through which cells can be sensitized to BCL2-family inhibitor treatment. I will use the cutting-edge technology CUT&Tag to assess the epigenetic landscape of MM patient samples with diverse anti-apoptotic dependence. The key aim is to identify targetable epigenetic modifiers that can be combined with BCL2 inhibitors for more effective MM therapy. I have 3 main objectives for this proposal: 1) establish parallel CUT&Tag with BH3 profiling to understand the basal epigenetic profile of MCL-1/BCL-2/BCL-XL-dependent MM; 2) to identify inter- & intra-patient epigenetic profiles characteristic of sensitive/insensitive patient samples; 3) to assess MM sensitivity to epigenetic inhibitors, and I will apply this basic research to drug development during a 6-week secondment in Almac Discovery. This project will deliver vital information on mechanisms of drug insensitivity & therapeutic avenues to target epigenetic sensitivities in MM tumors. At this critical stage in my career, it is crucial that I further diversify my skillset and apply interdisciplinary tactics to my research questions. Winning the prestigious MSCA-PF will allow me to expand my skillset, gain i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Decode and Cure primary Focal Segmental Glomerulosclerosis' (CureFSGS) under Horizon Europe.

assistant: **Objectives**

Kidney diseases are a worldwide rising major health problem associated with an excess risk for cardiovascular disease and reduced life expectancy. While general risk factors for kidney diseases such as diabetes and hypertension are being addressed through numerous research efforts, causes of specific glomerular kidney diseases, especially Focal Segmental Glomerulosclerosis (FSGS), remain poorly understood. FSGS is the most common glomerular cause of end stage renal disease characterized by scaring of the glomerular kidney filters and podocytes loss. Until now, the development of specific therapies has been hindered by the poor stratification of FSGS entities and the lack of understanding of immune mediated forms of FSGS. CureFSGS will establish a new strategy to identify key factors in FSGS: First, CureFSGS will develop a molecular classification of FSGS entities by utilizing a worldwide unique kidney sample repository/ registry combined with a novel analysis pipeline of single cell analytics, multiplex imaging and machine learning-aided image analysis to guide clinical decision making and to provide novel molecular insights. Second, CureFSGS will precisely decode immune mediators of FSGS and systematically map the podocyte response towards immune actions by devising a novel complementary platform of immune cell analytics and podocyte in vitro, ex vivo perfused kidney, in vivo as well as human organoid systems.  Third, CureFSGS will ultimately precision target the identified immune cells, soluble immune factors or podocyte injury pathways by newly developed cell-specific AAV- and nanobody strategies. Together, CureFSGS will set the stage to finally understand and treat FSGS effectively.


**Keywords:** Translational medicine, nephrology, kidney physiology