RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Expressing Value in Language' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Evaluative adjectives—words like ‘good’, ‘ugly’, ‘tasty’ and ‘elegant’—have interpretations that appear to depend on the context. If you describe a knife, a bear or an act of charity as ‘good’, you do not seem to be saying that it has some fixed property of goodness. Rather, the context in which you are speaking affects the interpretation of ‘good’. Evaluative adjectives are closely linked to concepts of central importance in philosophy, such as moral goodness, beauty, and value. Hence their apparent context-dependence has troubling consequences for many philosophical debates. For example, an act of charity could count as ‘good’ when we are talking about it in one context and as ‘not good’ when we are talking about it in another context, due to different interpretations of ‘good’. This startling conclusion is difficult to reconcile with most ethical theories. While philosophers and linguists have shown increasing interest in evaluative adjectives, a full analysis has remained out of reach for several reasons. First, philosophical and linguistic investigations often proceed in isolation from each other. Second, the scope of analyses can be overly specific, by virtue of focusing on a single case-study, or overly general, by focusing on features that supposedly unify all evaluative adjectives. Third, the predictions that emerge from different analyses are rarely subjected to empirical assessment.The project aims to give an account of the meaning of the word ‘good’ and other evaluative adjectives, along with the nature of goodness and other forms of value. It will be the first fully integrated analysis, by incorporating philosophical and linguistic perspectives, generalisations about evaluative adjectives and particular case-studies, along with empirical results. The novelt
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Ancient Egyptian floral arrangements: a modern analytical key for the identification of their plant species and the study of their operational chain' to be submitted under Horizon Europe.

assistant: **Abstract**

The peculiarity of Egyptian archaeobotanical material has created many difficulties in its study over the last two centuries. Floral compositions (dry ancient garlands and bouquets found in tombs of the Pharaonic and Greco-Roman periods) have no comparison in Mediterranean and European archaeobotany, as they preserve parts of dehydrated plants with which the archaeobotanist has commonly not been trained to compare and study. The result is that to this day, many floral arrangements found in contemporary excavations remain unpublished, creating gaps in information regarding ancient Egyptian flora and cultural practices that use flora as raw material. The project will therefore focus on the development of specific identification tools for the plant species of this material available to all archaeobotanists who may find themselves dealing with Egyptian material. The numerous floral compositions preserved at the UCL Petrie Museum and Kew Gardens will be used as ancient material to develop valid species identification criteria. The project will propose identifying morphological characters of the species which can be established primarily with low magnification observation, and only secondarily with the collection of thin sections to be observed under a light microscope or samples for the SEM. The result will be a specific protocol and an analytical key for the analysis of ancient Egyptian floral compositions which will finally also bring greater uniformity in the identification of the species of floral compositions and their publications. Furthermore, all dissemination phases of the project will try to involve the ongoing archaeological excavations in Egypt as much as possible, to create a fruitful and mutual exchange on the presence and study of this material. Finally, the r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Supporting sustainable participation of industry, in particular high-technology, research-intensive SMEs in EU-funded research in the Health Sector' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Fit for Health 2.0 aims to promote and enhance a sustainable participation of European industry in the Health-related sector of Horizon 2020 (H2020). Focusing on research-intensive, high technology SMEs the project offers targeted support measures, covering the entire innovation cycle of research projects. Key assets are highly qualified advice and support including a mentoring and coaching approach, hands-on trainings, effective SME-academia matchmaking and guidance to use H2020 more strategically. SMEs and researchers will be supported during all phases of research projects, including first orientation, consortium building, proposal writing, project management and efficient valorisation of project results. Cooperation between SMEs and academia will be strongly encouraged by dedicated services and tools and using new media. A well established, highly visible database with a sophisticated matchmaking-tool together with the complementary BiotechGate database will support the formation of competitive project consortia. H2020-Partnering Days will provide excellent interaction platforms for SMEs and academia. Target group-specific on-site and virtual trainings for H2020 starters, applicants and participants of running FP7 Health-, IMI- and EDCTP projects will be a hallmark of the project. Partnering Days and trainings for exploitation will support SMEs and researchers in successfully bringing their project results to the market. A mentoring and coaching approach and strategy trainings will support SMEs and clusters for a sustainable participation in H2020. The consortium builds on the success of the running project Fit for Health. Highly experienced NCPs and Enterprise Europe Network-members together with renowned senior trainers on innovation, technology transfer, financin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Pan-european network for ageing muscle' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

A striking effect of increasing age, even in health, is progressive muscle weakness. This affects the ability to perform simple, but essential physical tasks and results in less independency and reduced quality of life. Muscle weakness is product of loss of muscle mass and quality. This may be linked to older people having an impaired ability to up-regulate muscle growth factors in response to exercise, which is the only known mean of enlarging muscle contractile content admass, and thus, improving muscle function. However, it is our hypothesis that twill is possible to amplify the growth factor and repair processes with specifically designed nutritional interventions that are targeted at enhancing these specific mechanisms at the transcriptional and transactional levels. Thereby, combined physical training and nutritional supplementation will improve muscle function in the elderly more than can be achieved with either alone.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Restoring Mueller glia cell – photoreceptor interactions with Crumbs' under Seventh Framework.

assistant: **Concept**

Mutations in the Crumbs homologue 1 (CRB1) gene cause photoreceptor degeneration resulting in progressive retinitis pigmentosa (RP) or Leber congenital amaurosis (LCA), which both currently are untreatable blinding diseases. CRB1 is localized in Mueller glia cells at a subapical region (SAR) adjacent to adherens junctions between Mueller glia cells and photoreceptors. Loss of CRB1 function results in loss of adhesion between Mueller glia cells and photoreceptors. This ultimately results in the death of photoreceptors and other retinal neurons with loss of vision at birth (LCA) or before the age of 20 years (progressive RP). Using fruitfly and mouse genetics we will analyze the biochemical, cellular, developmental and physiological functions of CRB1, its family member CRB3, and CRB1-interacting-proteins PALS1, PATJ and MUPP1, in function of the SAR and its role in cell-cell interactions. We will analyze the effect of loss of interaction between Mueller glia cells and photoreceptors and subsequent retinal degeneration in retinas lacking both CRB1 and CRB3, or lacking the CRB1-interacting protein PALS1. To further understand the role of these proteins in neural-glial interactions in general, we will also assess what role these molecules play during development. To develop a cure restoring the impaired interaction between glial cells and photoreceptors, we will explore the efficacy of Mueller glia progenitor cell transplantation in mouse retinas. In collaboration with a small enterprise we will also deliver clinical grade adeno-associated viral (AAV) gene therapy vectors to transfer and express human CRB1 specifically in Mueller glia cells lacking CRB1 function. At the end of the project we will develop a demonstration project using these vectors in clinical phase I/II test
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'P53-dependent Metabolic and Epigenetic Reprogramming in Carcinogenesis', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Carcinogenesis is a multi-factorial disease which combines genetic mutations, aberrant epigenetic landscape and altered cell metabolism. TP53 which is the most mutated gene in human cancers, is known to regulate cell metabolism. It has been recently established that the metabolic status of cells can modulate the epigenetic landscape. The goal of this proposal is to characterize metabolic-driven modulation of epigenetic landscape during carcinogenesis using TP53 mutated cancers as models. In this project, we plan to address how TP53 mutations alter cell metabolism and the epigenome, thus creating abnormal gene expression facilitating carcinogenesis. Thanks to our preliminary data we will focus our attention on Acetyl-CoA metabolism and histone acetylations. This project will take advantage of state-of-the art approaches such as metabolomics, epigenomics and transcriptomics. My expertise on epigenetics and metabolism, as well as the expertise of the supervisor in the field of TP53 and carcinogenesis, are major assets for this project. Altogether, we expect that unraveling novel mechanisms interconnecting TP53 mutations, cellular metabolism and epigenome will provide new insights for understanding cancer development. Moreover, we expect to propose innovative strategies to tackle cancers harboring mutated TP53 thanks to combination of drugs targeting metabolism and the epigenome. This fellowship will definitively help me to conduct a unique and promising research line in the European Community with the final goal to establish myself as an independent scientist.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Technology for the implementation of a standard european code in the carpet industry improving a closed loop system' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

In Europe, a yearly amount of approximately 1.7 mio tons of textile floorcoverings have to be disposed of. Until now their is no lable or code onto carpets content informations about materials or recycling options. So this project will create a coding system that will enable a reduction of the error rate in the sorting process from 20 to 10% and a reduction of the identification costs by 60%. The plarmed cost reduction is about 90 mio ECU per year. The necessary components of the coding-scarmer systems are the printer, the information and the scanner systems: . In the short term, the information technology can also be integrated in the company's QM system resp. used to create one. In the medium term, the code enables a consumer feedback plus constitutes a sales argument and in the long term it will enable the product's recycling. The implementation of the technology developed in the course of this project will establish a new European standard for codification and simple identification of textile floorcoverings to be recyded.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Effects of 3D topographies on mechanosensing in intestine epithelial architecture and dynamics' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Intestine epithelium consists of spatially segregated cells that organize into groups of various functions at different locationsof the 3D curved epithelial monolayer. How geometric cues contribute to the maintenance of the sophisticated epithelial architecture and dynamics in 3D remains unknown until now. Recently, the Ladoux's laboratory has found that EpCAM-modulated cell contractility associated with the epithelial monolayer polarity, cytoskeletal arrangement, and cell-cell adhesion in 3D context. In contrast to 2D context, the EpCAM-defective tissue shows a loss of collective cellular spatial organization and forms a disordered multi-layered epithelium when exposed to substrates of 3D topographies. In addition, Ankyrin-G and α/β-spectrin network which participates in cortical tension modulation was identified as the main interacting partner with EpCAM in epithelial cells. These observations lead us to hypothesize that EpCAM allows the tissue to sense and conform to complex 3D topographies in an orderly manner. However, the molecular mechanisms and other related functions of EpCAM-mediated mechanotransduction remain unknown. As large scale mechanosensing has been shown to occur primarily through the actin cytoskeleton which permeates the tissue to form a network, we aim to understand the interactions between the EpCAM-mediated pathway and actin modulation and/or E-cadherin adhesion sites that may allow 3D topographical sensing. Our working hypothesis is that EpCAM forms an integral part of the cellular responses to topographic cues that has a more general role in controlling epithelial architecture and dynamics through the regulation of actomyosin networks, or vice versa. Here, we propose to scrutinize EpCAM-mediated mechanotransduction by generating a platform with
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Adhesive Connection for Secondary Structures in Offshore Wind Installations' in the context of a Horizon 2020 call.

assistant: **Objectives**

The development of floating (offshore) wind turbines on a commercial scale is expected to grow considerably over the next few years after that different countries have recognized them as the best solution for the production of sustainable energy. In order to satisfy the required needs of safety, serviceability, durability and affordability, the actual connections and the secondary structures have to be replaced by a new ones based on the bonding technique. The ASSO project has the principal purpose to establish a sound framework for the feasibility and assessment of adhesive connections for offshore wind installations in the marine environment, including experimental tests and accurate numerical procedures. In this framework, the ASSO project aims to develop: an innovative non-linear mechanical model able to investigate the influence of seawater on the performance of adhesive connections in the presence of leading causes of degradation, ageing and vibrations (due to the waves); an experimental database in order to predict their service life investigating the long-term behaviour and resistance in seawater environment. Consequently, in order to increase the knowledge of adhesive connections in the marine environment, the project is composed of the following three different levels: experimental tests, non-linear mechanical model and FEM analysis. The multidisciplinary nature of the project is strong, involving aspects of mechanical engineering, structural engineering, environmental engineering, applied mathematics, numerical analysis and advanced materials design. The proposal includes both the transfer of knowledge to the host institution and the training of the candidate in new advanced techniques. Results have the potential capacity to increase the diffusion of offshore
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Power performance assessment' (1994-1998).

assistant: **Innovation**

Objectives The overall objective of the project is to reduce the financial risk in investment in wind power projects by significantly improving power performance assessment for wind power plants. The immediate, measurable objectives of the project are to: - prepare a review of existing contractual aspects of power performance verification procedures of wind farms, - provide information on production sensitivity to specific terrain characteristics and wind turbine parameters by analyses of wind farms, - improve the understanding of the physical parameters connected to power performance in complex environment by comparing real-life wind farm power performance data with 3D computational flow models and 3D-turbulence wind turbine models, - develop the statistical framework including uncertainty analysis for power performance assessment in complex environments, and - propose one or more procedures for power performance evaluation of wind power plants in complex environments. Technical Approach Previous experience shows it is possible to significantly improve assessment tools. To do so, analysis of data and flow modelling is carried out distributed on three work packages. The first work package includes a review of contractual power performance evaluation procedures of wind farms; an evaluation of wind turbine power performance in wind farms with regard to time, wind dir., turbulence, wind shear, air density, inclined flow etc.; an analysis of the uniformity of wind turbines; an evaluation of alternative wind turbine power performance evaluation procedures. It includes wind turbine power performance modelling to reveal sensitivity to turbulence, wind shear, inclined yaw error, control strategy etc. with 3D turbulence power performance code. The second work package includes co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'GRANARIES AND WAREHOUSES IN NORTH AFRICA AND EGYPT DURING THE ROMAN AGE. TYPOLOGY, BUILDING TECHNIQUES, FUNCTION, PRODUCTIVE CONTEXT' (GRAWINAE) under Seventh Framework.

assistant: **Objectives**

The present project aims at presenting an interdisciplinary way of looking at the history of the African grain in Roman age, in particular from the 1st century BC to the 5th century AD, starting from the data that can be found at archaeological level. The project of starting a new research arises from the lack of a comprehensive study, sufficiently updated and complete, considered all noticeable evidence emerged from the excavations of the past forty years. The present study intends to develop and to deeply investigate grain provision in the Roman provinces of the Mediterranean coasts/shores in North Africa (actual Morocco, Algeria, Tunisia, Libya, Egypt), shifting the perspective to the study of granaries as containers, to their technological aspects and productive contexts. The matter of this project will be techniques of construction, interior arrangement/layout, storage system, evaluation of thermo-igrometric conditions, grain species, climatic conditions, lithology and pedology of the soils. Where were the store buildings located? Who built them and which were the architectures and techniques used? How were the seeds preserved? How was the production organized? Which were the best soils? Which were the cultivated species? The innovation of the project consists in using different methodologies: archaeological investigation; stratigraphic analysis and application technologies; geophysical prospection (magnetic method); use of the custom-made softwares to calculate storage capacity of the building and to evaluation of thermo-igrometric conditions. During the project will be carried out the geoarchaeological study (paleo-environmental conditions of the site, dynamics and the evolution of soils) and the anthropological investigation of traditional storage system. Anothe