RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Nonequilibrium quantum fluctuations in superconducting devices' in the context of a Seventh Framework call.

assistant: **Objectives**

In the last fifteen years we have witnessed to an impetuous advancement in the theory of nonequilibrium fluctuations, triggered by the discovery of a number of relations, collectively known as Fluctuation Theorems, which link the full nonlinear response to equilibrium thermodynamic properties. Experimental investigations of these exact relations in the quantum regime is yet in its infancy, while we are currently witnessing a growing interest into these relations by the experimental condensed matter and quantum information communities. In an effort to stay at the forefront of new developments, this project aims at proposing feasible experiments where quantum fluctuation relations can be verified and applied. This will be achieved by pursuing two objectives, the first concerns the verification of fluctuation relations, the second their application. In both cases we will focus on experimental set-ups involving solid state superconducting devices. These are very promising tools for the development of future quantum technologies. Our first objective is to develop concrete and feasible proposals for circuit QED experiments aimed at measuring the work statistics and verifying the fluctuation relations in the quantum domain. Our second objective is to use fluctuation relations as a tool for improving the thermodynamic efficiency of solid state devices. In particular we will focus on a device, the Cooper pair pump, which hold a promise for geometric quantum computation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Strongly correlated ultracold fermions in two-dimensional tailored optical potentials: pairing, superfluidity and disorder' (SCOUTFermi2D) targeting Horizon 2020.

assistant: **Abstract**

Two-dimensional fermionic systems exhibit some of the most remarkable phenomena in modern physics, combining fundamental aspects with a high technological impact. Their peculiar and rich behavior arises from the interplay between quantum statistics, dimensionality and strong interactions, which also makes their theoretical treatment extremely challenging. This project proposes to explore the physics of strongly correlated fermions in different two-dimensional (2D) landscapes with an ultracold gas of lithium atoms trapped in optical potentials. Ultracold quantum gases are in fact the ideal platform for approaching open problems in condensed matter theory and also an exciting toolbox for the search for novel synthetic phases of matter.The project aims to study fermionic superfluidity across the two-dimensional BEC-BCS crossover, unveiling its special nature by implementing advanced probing techniques such as high-resolution imaging and Bragg spectroscopy and suitable transport measurements that will reliably identify the transition to the superfluid regime. The investigation of first and second sound will be complemented by the study of the coherent Josephson tunneling between two weakly coupled 2D superfluids, a strong evidence of macroscopic phase coherence. By adding disorder, we propose to address the debated metal- and superconductor-to-insulator transitions in a pure controllable fashion, providing new insights into longstanding debates.Finally, we propose to realize three-components Fermi gases with controllable interactions, enhancing their stability in 2D. This will allow for approaching more exotic topics such as color superfluidity and trimer formation, linking our research to quantum-chromodynamics (QCD).An experimental machine has been already set up for the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Epigenetics of Bladder Cancer Evolution.' (Epi-BCE) targeting Horizon Europe.

assistant: **Abstract**

Cancer is one of the leading causes of death worldwide and its management remains challenging. Tumor evolution, the process of genetic and epigenetic divergence and selection of cancer cell clones in a heterogeneous tumor, is a key aspect of disease progression and therapy resistance. The main goal of this proposal is to expand our understanding of the biological mechanisms involved in these processes. So far, the role of chromatin regulation and epigenetics in tumor evolution remains poorly characterized and understood. This is particularly relevant in bladder cancer where mutations in chromatin regulation are very frequent and are associated with advanced and therapy resistant disease.Epi-BCE will advance the state-of-the-art through the discovery of epigenetic mechanisms that drive bladder cancer progression and chemoresistance in cell subpopulations, and tumors with chromatin deregulation. Specifically, I will utilize a carcinogen-based mouse model of bladder cancer that recapitulates human cancer stages from early to advanced and therapy resistant disease. I will perform transcriptomics and epigenomics at bulk and single-cell level at stages of disease progression. In addition, I will employ genetically engineered mice with ablation of chromatin regulation proteins, integrative computational analysis and functional genetic experiments to identify key mechanisms. Epi-BCE will be a platform for professional growth. I will receive technical training in experimental mouse models, bioinformatics, and 3D genomics through a secondment. I will engage in new professional networks and acquire transferable skills. Grantsmanship activities will support the fellow towards a path to independence.Overall, the proposed experiments will yield scientific knowledge and reusable datas
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Synapsing Mental Disorders and Neurodegenerative diseases: Towards more effective diagnosis and management of psychiatric symptoms' (SYNAPSING) under Horizon Europe.

assistant: **Objectives**

Disrupted neuronal connectivity and synapse dysfunction can manifest clinically as a range of emotional, behavioural and cognitive symptoms that are common to, and often overlapping in, mental disorders (MDs) such as major depressive disorder, bipolar disorder and schizophrenia and neurodegenerative disorders (NDs) such as Alzheimer’s disease and Parkinson’s disease. Antidepressants and antipsychotics used to treat these symptoms are often ineffective in ND patients and treatment-resistance is common in MD patients. To tackle the burden exacted on society by untreated psychiatric symptoms, Synapsing will generate the first trans-European clinical collection of clinical, neuroimaging and socioeconomic data from >3000 patients from MD and ND clinics for use in Synapsing and beyond. Synapsing aims to introduce a biological framework for MDs through a search for blood biomarkers to engender a faster, more objective diagnosis and reduce misdiagnosis with NDs. To minimise the use of inefficient treatments across MDs and NDs, Synapsing will develop blood biomarkers to objectively monitor therapeutic response and to stratify patients who would benefit from therapeutic intervention. To guide the development of more effective treatments, Synapsing will model synapse dysfunction using post-mortem brain tissue and induced pluripotent stem cell derived neurons from MD and ND patients. To prevent social disparities impacting on healthcare, Synapsing will identify modifiable socioeconomic risk factors for psychiatric symptoms in >2000 individuals with a lived experience of mental health issues and MD and ND patients recruited across Europe. Recommendations for evidence-based policy initiatives targeted towards reducing these risk factors will be disseminated to EU council agencies. Ex
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'A Novel Nano-container drug carrier for targeted treatment of prostate cancer'.

assistant: **Concept**

The essence of the proposal is the fabrication of multiple nano containers which exhibit double and triple stimuli response and site recognition. Specifically, the containers will be grafted by Leuprolide (LP) for prostate cancer recognition. Multiple containers will be filled by two drugs (e.g. LP and DOX) in different compartments not interacting with each other chemically (cocktail of drugs, e.g. Container1 Leuprolide (LP) and Container2 Doxorubicin (DOX)). The release can be excited by internal or external stimuli response. The internal stimuli response of our nanocontainers will require simultaneous recognition of pH, redox and/or T of the tumour. The external induction will be caused by RF excitation (hyperthermia). The nanocontainers will identify the tumour first by the agonist (LP). After trapping the container at the tumour, they will be activated by the double and triple internal excitation. This way, we achieve extremely local chemotherapy of the diseased site and the healthy organs will be untouched. Our smart nanocontainers will be tuned for prostate cancer, but our system will be evaluated for other cases such as breast cancer and thrombosis. The containers will be modified (phase transition, volume change, degradation, etc.) and deliver the drug only and if only the two sensors give positive response. The containers can be excited by external induction (Radio Frequency (hyperthermia) RF or laser light). This revolutionary strategy is necessary because the externally induced delivery methods have the disadvantage that the radiofrequency fields, the magnetic fields and the laser lights are not local but they extend over large space, larger than the size of the tumour. One cannot focus from outside the laser beam directly to the tumour only may be due to la
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Presence: Research Encompassing Sensory Enhancement, Neuroscience and Cognition, with Interactive Applications'.

assistant: **Objectives**

This project aims to develop a theory of presence in virtual environments (VEs) based on empirical observations from neuroscience and other experimentation. The data will go far beyond the usual subjective questionnaires that have been at the root of presence research to date, and will include brain imaging studies, physiological measures, eye tracking, behaviour and subjective reporting. The second aim is to extend 'presence' beyond similarity of response between virtual and real stimuli, in order to exploit the capability of virtual reality for sensory enhancement and the plasticity of the brain in learning to carry out actions in new ways. This will enable carrying out of activity by 'thought'. Another application will be communications between remotely sited people sharing a VE. The goal is to portray not just the geometry of individuals, and their motor actions, but a range of other information such as empathic responses and physiological condition. This will explore how communication is affected by visualisation of as much as the total state of a person as is possible (and desirable). The impact of such sensory enhancement on presence will be explored. This project aims to develop a theory of presence in virtual environments (VEs) based on empirical observations from neuroscience and other experimentation. The data will go far beyond the usual subjective questionnaires that have been at the root of presence research to date, and will include brain imaging studies, physiological measures, eye tracking, behaviour and subjective reporting. The second aim is to extend 'presence' beyond similarity of response between virtual and real stimuli, in order to exploit the capability of virtual reality for sensory enhancement and the plasticity of the brain in learning to car
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Exploring Bose-Einstein Condensation of Excitons and Related Quantum Phases' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

This research proposal aims at harnessing collective quantum phenomena in semiconductors in order to deterministically engineer quantum states of matter. For this purpose, the techniques successfully pioneered in atomic physics will be transposed to the solid-state. As envisioned by R. Feynman, this approach offers the formidable opportunity to emulate emblematic collective quantum phenomena and to radically deepen our understanding of quantum physics. At the same time, it opens a route to develop a novel generation of  devices that have direct applications in the context of quantum information science. The ambitious goal of the project will be pursued by employing the unique physical properties of spatially indirect excitons confined in bilayer semiconductor heterostructures. Indirect excitons are boson-like quasi-particles which exhibit a very long lifetime and a well defined electric dipole. These will allow us to engineer a complete toolbox for the quantum control of the exciton wave-function. To this aim, we conceived an innovative approach where an advanced technology for trapping indirect excitons is enriched by quantum optical techniques. Thus, a scheme is elaborated to unambiguously demonstrate Bose-Einstein condensation of semiconductor excitons. Precisely, this research proposal introduces two main objectives: i) the realization of microscopic trapping potentials where the effective temperature of exciton gases is dynamically controlled. ii) the development of artificial lattices to engineer exciton crystals and develop a solid-state quantum simulator. Reaching these objectives would lead to an unprecedented level of control over ultra-cold exciton gases. This would open new horizons in order to study the foundations of quantum many-body physics and to develo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Implementation of agents for cac on an atm testbed'.

assistant: **Innovation**

Main ObjectiveThe overall objective of IMPACT is to implement control strategies on an ATM testbed as a society of interacting/co-operating agents. The work will use the EXPERT platform in Basel and will interconnect the switch on which the agents are implemented with the existing testbed network in order that the performance of the agent approach may be tested.The application will concentrate on Connection Admission Control (CAC) but to demonstrate the attractiveness of agents in controlling co-operating functions, the work will also introduce an accounting/charging agent. The project will also validate the FIPA model for agent management and communication in the context of a real time distributed telecommunications environment.Technical ApproachExisting applications will communicate with a signalling entity in a new switch, the FLEXTEL switch, to request a new connection; that entity will have an agent wrapper to allow it to communicate with the CAC agent which then requests resources brokered by other agents. Once a connection end-to-end has been negotiated, the CAC agent informs the signalling (and hence the application) that the connection has been set-up and user-to-user transfer of data can start. The CAC agent will also notify the charging agent of the parameters to be used for charging and, in this simplified model, data from the Usage Parameter Control (UPC) function will be used by the charging agent to calculate the actual cost. It should be noted that here it is assumed that the switch connection is also initiated by the CAC agent through a switch interface function.Where an agent function is installed in the terminal, control-plane communication is entirely by the Agent Control Language (ACL) (through a user agent); the advantage of this approach is that i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Smart Acoustic house' in the context of a Fourth Framework call.

assistant: **Objectives**

Objectives and content Quality and comfort of private and public buildings is - to a considerable extent - assessed by the acoustic climate inside the building. Disturbing noise comes through windows, doors and lightweight internal walls with poor sound insulation capacity, especially at low frequencies. Disturbing reverberation and reflections are often present in public buildings with large areas of hard walls and ceilings, but also in private living rooms reverberation and reflections can severely prevent good music listening conditions. The increase of sound insulation of walls, windows and doors is essential in increasing the quality of the acoustic environment. Traditionally this is done by increasing the thickness and weight of walls and door panels, increasing the absorption material inside double leaf partitions and increasing the number of glazing layers of windows. However, these add weight and cost of building elements and make the construction complicated. The main industrial objective of the research is to demonstrate a major breakthrough in the development of active control of sound (ACS) systems for buildings. They can increase the comfort and reduce the thickness, weight and cost of building elements. This can be achieved by using high efficient flat film actuators as anti-noise sources. The technical innovation, ElectroMechanical Film (EMF) can be used as an acoustic source. The actuators made of EMF are very thin, weigh very little, are mass-producible and thus cheap. They can be placed on all desired places on walls and ceilings and inside double leaf partitions. In existing buildings noise reduction using ACS can be more efficient and extended to higher frequencies. In future buildings light-weight panels on which the EMF actuators are fixed can hav
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Facilitating a digital single market in Europe through cross-border alliances' (DSMFACIL).

assistant: **Innovation**

“Nearly all growth in retail comes from e-commerce” states E-commerce Europe, as online sales in Europe grew by 13.3% while the growth in total retail sales merely reached 1% in 2015. However, cross-border sales constituted only 10.6% of Europe's total online sales in 2013, despite the European Commission’s (EC’s) estimate of €415 billion annual contribution to European economy from a European Digital Single Market (DSM), which is currently one of the top priorities of the EC. Besides language barriers and differences in legislature across the EU, the EC states that low engagement can be attributed to: 1) high compliance and delivery costs, 2) low consumer trust regarding foreign retailers’ delivery and after-sales support, and 3) low consumer awareness of foreign retailers. The EC has proposed several trade policy measures to facilitate a DSM. Yet, complementary operational business strategies that enable cross-border profitability under aforementioned challenges have not been explored, while trade measures are still under way. This project aims to develop an interdisciplinary modeling and optimization framework in order to study the dynamics of cross-border alliances between retailers for enhanced cross-border customer acquisition, distribution, and after-sales support. This much-needed framework will provide timely and reproducible models, leading to win-win horizontal cross-border alliances that leverage unique strengths of local retailers under high distribution and compliance costs, low cross-border consumer awareness, and consumer concerns on cross-border delivery and after-sales support. To that end, an interdisciplinary research that uses econometrics, economics, systems dynamics, and optimization literatures will be conducted to create models that can be trans