RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Advanced ultra sensitive and ultra rapid methods for microbiology testing in the pharmaceutical and water industries' in the context of a Fourth Framework call.

assistant: **Objectives**

The microbiological control in industrial contest , is still today majority based on growth capability on standard medium. This approach is time consuming allowing only retrospective actions . In addition it is now recognized that some micro-organisms may not be cultured while maintaining a viability . Over the last 20 or so years no alternatives have been developed to fully substitute the official plate count technique.The objectives of the proposed research and development project are to develop and validate for industrial routine applications , new ultra rapid techniques for microbiology testing. The analytical procedures developed will have to meet the needs of the pharmaceutical and the water industries and their performance will be tested in actual plant environment.A sterility test based on esterase activity and membrane integrity has been developed ; this test allow the detection of viable micro-organisms down to one cell per volume filtered within 3 hours for a TVC (total viable count). It has been validated on a large number of micro-organisms and showed a good correlation with the traditional plate count method. The initial validation on pharmaceutical products have revealed the presence of false positives which have been later on eliminated by addition of a counter stain in the protocol ; the improved protocol is now proposed to several pharmaceutical plants for internal acceptance. Specific detection of E. coli has been approached by using the in situ hybridation technique ; application to naturally water samples has shown the requirement of a signal amplification due to a low level of ribosomal RNA which can be achieved by additional enzyme amplification. The total reaction time, however, exceed the two hours objective. An improved hybridation approach usi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Use of organoclays in bioremediation of contaminated soils and groundwater', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

The objectives are the development of fundamentals for effective biodegradation approaches combining biological and physicochemical processes as the use of organ clays in reactive barriers for pollution control. The principles base on a combination of adsorption and biodegradation in a defined matrix, which provides contaminant elimination and sorbet regeneration. The requirements of reversible sorption processes and sufficient compatible milieu for bacteria are met by the use of organ clays. The combined use of bacteria and andorganoclay under static conditions has been investigated in detail recently. The main focus will lie on column techniques under flow conditions based on interactions between organically/aquifer mixtures, chloroaromaticcompounds and bacteria. Development of mixtures of organ clays and aquifer material as a packing material having both a significant sorption capacity for chloroaromatic compounds and a sufficient hydraulic conductivity, because of the low hydraulic conductivity of pure organ clays. Because particularly attention has tube turn on the compatible milieu for bacteria, one of the main training objectives for Time Pertness is an extended introduction in the field of microbiological aspects of soil remediation. Particularly the aspects of controlled microbial degradation of organic contaminants in soils or aquifers are of importance in order to complete her previous experiences from her PhD work in soil remediation based on sorption processes andphotooxidation. In fact, the investigation and the optimisation of such a system meet a scientific challenge and provide valuable information on the applicability of organ clays for bioremediation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Development and plasticity of auditory spatial coding in the midbrain' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

Sensory experience is used to align maps of visual and auditory space in the midbrain during development. I will investigate factors that contribute to the maturation of the auditory map and the site of action of activity dependent plasticity in this representation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'An investigation on carbon and energy exchanges of terrestrial ecosystems in europe' under Fifth Framework.

assistant: **Concept**

Problems to be solvedRecent studies have shown that a significant portion of the net terrestrial uptake of CO2 must occur at mid-latitudes of the Northern Hemisphere of which European terrestrial ecosystems cover a significant area. However, the magnitude, location, temporal behaviour and causes of the carbon source/sink strengths of terrestrial ecosystems are not very well known making the implementation of the Kyoto Protocol still under strong debate.Scientific objectives and approachThe aim of this project is to quantify the magnitude of the carbon sources/sinks for a range of terrestrial ecosystems, in respect of species, age, climate, nitrogen loads and geographical locations. This includes the investigation of effects of inter and intra-annual climate variations on the magnitude of carbon exchanges of terrestrial ecosystems. In addition the role of soil, wood and leaves biomass respiration on the partition of the ecosystem carbon exchanges will be studied. Ecosystem modelling studies on carbon sequestration across a range of climate, species and vegetation structure will accompany field studies. The project is based on measurements of carbon and energy fluxes on 32 terrestrial ecosystems of the European continent, representing various species, community structure, management practices and distribution with respect to the range of European climate conditions. The selected sites fall into four main climate classes: Mediterranean, Temperate - Atlantic, Temperate - Continental and Boreal. The major forest biomes are constituted by deciduous (beech, turkey oak) and evergreen (pinus, spruce, helm oak) forests. In these sites the inter-annual variability of carbon fluxes will be investigated. The methodology for ecosystem exchanges of carbon and energy is based on the ed
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Virtual Laboratories for Exoplanets and Planet Forming Disks' (CHAMELEON) under Horizon 2020.

assistant: **Objectives**

The first detection of an exoplanet marked a new epoch in our hopes to detect extraterrestrial life. These detections have opened new parameter spaces and demonstrate that physical and chemical conditions exists in (A) planet forming disks that are vastly different from what we know in the solar system and in (B) (exo)planets that are vastly different from those that characterized planet Earth when life originated in an anoxic soup, and yet could allow for life-bearing chemistry to occur. In this MC-ITN, we focus on the development of Virtual Laboratories which will be the crucial tool to analyze in detail current and future disk and exoplanet observations, and for filling the gaps of incomplete observational data.  Our Virtual Laboratories will use advanced numerical and statistical methods that comprise input from astrophysics, computational chemistry, laboratory and theoretical physics, geosciences, mathematics, and computer sciences. Virtual laboratories play  a key role in simulating yet unexplored physico-chemical environments.  Our 3 major objectives are:  -- Scientific:  Retrieve and predict the chemical composition of planet-forming disks and exoplanet atmospheres. -- Technological: Knowledge transfer between planet and disk community by the exchange of state-of-the-art codes. Apply and develop models of different complexity as link between big observational and numerical modelling data. Explore models as Virtual Laboratories for parameter spaces that cannot be reached by observations nor by (laboratory) experiments. -- Educational: Train complex modelling and big-data interpretation. Use fascination for exoplanets and their birthplaces to promote science in the society and in the local and wider communities due to dedicated art & education and art & science pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Solid sorption cooling in tri-generation (SOCOOL)' (SOCOOL).

assistant: **Concept**

Title: SOCOOL - Solid Sorption System for Cooling in Tri-generation Objectives and problems to be solved: The project is focused on the development of a small-scale combined cold, heat and power (tri-generation) system, which utilises the engine waste heat for cold production. Development of this tri-generation system will lead to improved exploitation and more effective use of CHP systems. The general objective of the project is to reduce primary energy usage and to avoid CFC/HCFC/HFC usage for cooling purposes. This contributes to the achievement of the Kyoto targets and to the development of more sustainable energy systems and services, to the diversity of energy supply, and will reduce the environmental impact for cooling, heating and power generation. An increase in the overall energy efficiency of tri-generation systems of 15-20% will be realised by utilisation of the waste heat of a CHP system for the production of cold by means of solid sorption cooling technology. In addition peak electricity demands for cooling purposes will be reduced. The major issue is the development of a small solid sorption system with high power density, by applying new working pairs as well as innovative system designs to achieve high rates of heat and mass transfer. The new cooling machine developed within this project will be low in cost (cheap to manufacture), will have a high efficiency, and must operate with a high reliability. Description of the work: The consortium will produce an update of market prospects, characteristics, and trends for cooling applications in the residential sector and will determine the most promising field of application for the solid sorption cooling device in a tri-generation system. Specifications for the cooling machine will be established and solid so
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'In-Seat Ventillation and Supply for Personalised Comfort Control on board an Aircraft' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The COCOON project will develop and demonstrate integrated seat climatization, ventilation and air supply system, maturing the technology bricks to TRL6 for a standard economy 3-seat row with a target weight of <1kg to achieve personalised comfort control and a 2% fuel saving through reduced thermal load at the cabin level. Thermoelectric heating and cooling modules combined with a ventilation and air supply system will be controlled via a tablet or smartphone to provide advanced in-seat personalised microclimate control. The project will leverage previous work by UTRC which developed an in-seat microclimate control module for the business jet market by adapting it to the economy sector. UTRC Ireland will work with UTAS GEC Poland to design, test and validate a prototype of the system which will be integrated into BE’s current economy 3-row seat configuration and tested at the BE facility in Kilkeel, Northern Ireland.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Towards better point of care devices: Conducting polymers as smart surfaces in biosensors' (CP-SMARTSURFACES) under Seventh Framework.

assistant: **Objectives**

Discovered just over 20 years ago, conducting polymers (CPs) have gained considerable attention because of their unique chemical and electronic conducting properties. As a result they have various (bio)analytical and technological applications. CPs are easily synthesised, both chemically and electrochemically under mild conditions, opening up vast possibilities for the immobilisation of biomolecules. Immobilisation of antibodies by entrapment within films or by covalent binding on these films permits the straightforward fabrication of biosensors. In electrochemical biosensors, non-specific binding (NSB) of molecules, e.g. proteins in serum, can occur, lowering overall device performance. In the past, surface chemistry has been employed to prohibit NSB on electrodes with sites that do not have antibodies attached. This surface chemistry however, impairs device performance. CPs have inherent dynamic surface properties that can be easily switched upon the application of an appropriate electrical potential. Their ability to be switched between different oxidation states and the associated switch in properties such as doping level, resistance and surface wettability can be controlled by changing the electrical potential resulting in reversible switching. Routes to nano-dimensional CPs, exhibiting markedly improved properties from those of the bulk materials, have been recently developed. We therefore propose to exploit the dynamic chemical nature of CPs to inhibit NSB in electrochemical bio-assays and demonstrate the efficacy of this approach using a simple nanostructured electrochemical prostate cancer diagnostic platform made from conducting polymers. One can imagine the significance of a biosensor that provides increases in performance and shorter detection times, since t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Live Tapings of Material Formation: Unravelling formation mechanisms in materials chemistry through Multimodal X-ray total scattering studies'.

assistant: **Concept**

With this proposal, I want to develop a new, multimodal approach to in situ X-ray scattering studies to unravel formation mechanisms of the solid state. The aim of the project is to develop a unified view of metal oxide nucleation processes on the atomic scale: From precursor complexes over pre-nucelation clusters to the final crystalline particle.The development of new materials relies on our understanding of the relation between material structure, properties and synthesis. While the intense focus on ‘materials by design’ have made it possible to predict the properties of many materials given an atomic arrangement, actually knowing how to synthesize it is a completely different story. Material synthesis methods are to a large degree developed by extensive parameter studies based on trial-and-error experiments. Specifically, our knowledge of particle nucleation is lacking, as even non-classical views on nucleation such as the concept of pre-nucleation clusters do not apply an atomistic view of the formation process. Here, I want to use new methods in X-ray total scattering and Pair Distribution Function analysis to follow nucleation processes to establish the framework needed for predictive material synthesis. One of the large challenges in studying nucleation is the lack of a characterization method that can give structural information on materials without long-range order. I have demonstrated that time-resolved X-ray total scattering gives new possibilities for following structural changes in a synthesis, and the use of total scattering has opened for a new view on material formation. However, the complexity of the structures involved in nucleation processes is too large to obtain sufficient information from X-ray total scattering alone. Here, I will combine X-ray to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Development of a novel replication-deficient mucosal rna vaccine protecting against respiratory viral disease of early childhood', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

The aim of the project is the development and the pre-clinical evaluation of a mucosal RNA-based virosomal vaccine against respiratory diseases of the early childhood caused by human parainfluenzavirus type 3 and respiratory syncytial virus. Antigens are encoded on a Sendai virus RNA packaged in a nucleocapsid and encapsulated into immunostimulating reconstituted virosomes. For an excellent safety standard, the nucleocapsid is completely replication-deficient by deletion of the N gene. Antigen combinations are provided by a single vaccine formulation in a modular system. The vaccine will be applied in a one step process and the administration as a nasal spray allows an easy reapplication. This makes the new formulation economic, effective, safe and highly adaptable for vaccination of humans (also of animals) against various infectious diseases.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Design and application at industrial scale of a new ultrasound device to enhance pigment dispersion in painting' (1998-2002) under Fifth Framework.

assistant: **Objectives**

Good pigment dispersion has always been a critical factor in the manufacture of a coating, because it is the most complicated and cost-intensive production stage in paint manufacture. This project deals with the development of a new industrial technology based on ultrasonic principles, which would increase, in a shorter time than usually, the pigment dispersion and so the qualities of paint. This proposed project intends to be developed through a European project. The different tasks of the project are to define water and solvents based pastes properties toward ultrasound and to develop the ultrasonic equipment for the prototype, which have to be validated from an industrial and economical point of view.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'DissEcting caLcium sIgnalinG in cHloroplasTs'.

assistant: **Concept**

The proposed training-through research project is aimed to address fundamental scientific gaps concerning plant’s stress responses to survive under nowadays-environmental cues (e.g., drought). This project will make myself as a major reference in Plant Physiology field opening up my career perspectives both in academic and non-academic realities devoted to biotechnological enhancement of plant performance and stress-tolerance.Being sessile, plants’ survival depends on sensing of the environmental changes and on the prompt translation of the sensory information into mobile signaling events within the cell, to trigger an adaptive response throughout the entire organism. Inside the cell, the chloroplast is a pivotal environmental sensor, and chloroplast signaling is indispensable for plant survival of abiotic and biotic stress as well as for proper development through concerted signaling events whose combined picture is mainly unexplored. The host laboratory has recently importantly contributed to this field by identifying chloroplast calcium transporters playing a crucial role in the response to drought stress. I will combine my expertise on monitoring signaling events in vivo at subcellular levels, with genetic and state-of-the-art tools developed by the host. These combined approaches will lead myself to significantly advance our understanding of chloroplast signaling responsible for adaptation and tolerance to drought stress, that will serve as springboard for future biotechnological investigations (dissections of chloroplast signaling in crops) as well as for priming plants for environmental cues ultimately leading to plant tolerance. Research breakthroughs together with complementary skills training will be extremely relevant for my career development, and the host l