RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'ASSESSMENT OF LIFE-CYCLE EFFECT OF REPAIRS ON TANKERS'.

assistant: **Concept**

In recent tanker accidents Erika and Prestige in European waters with catastrophic consequences, structural deficiencies may have largely contributed to the accident. Casualty investigation after the Prestige accident identified the need for better understanding in areas of the detecting of defects and weaknesses during and after survey and after repairs, the reduction of any adverse effects of repairs, current strength requirements for deck opening securing arrangements, etc. This Coordination Action project ALERT is proposed in response to this need. The ALERT project (Assessment of Life-cycle Effect of Repairs on Tankers) will undertake a thorough examination of current R&D practices of European industry in the field of ship repair and to propose improvements to the underlying processes in consultation with industry. The project aims to critically review the current and emerging technologies, identify and prioritise future R&D needs and developments in the areas of ship repair practices (WP1), Condition monitoring of ships (WP2), Structural assessment methodologies (WP3) and Through life management (WP4). Finally, the project will disseminate and exploit the results through publications, seminars and workshops and prepare R&D project proposals (WP5). The proposed ALERT project fits in very well to the objective of Research Domain 4.12 ?Developing technologies to sense and predict natural and infrastructure conditions affecting safety and efficiency of transport operations? on the following grounds: it deals with developing technologies appropriate for ship repair practices and sensing technologies to monitor ships; it promotes ship safety through maintaining structural integrity and efficiency through better monitoring, inspection, maintenance and repair scheduling f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Gene therapy of rheumatoid arthritis by means of cytokine modulation' (1994-1998).

assistant: **Innovation**

Rheumatoid arthritis (RA) is a chronic inflammatory systemic disease of unknown etiology. This project will investigate a gene therapeutic approach of trerating RA in animal models of arthritis, using novel cytokine modulating techniques. The proinflammatory cytokine tumor necrosis factor a (TNFa) has been clearly demonstrated to be of pivotal importance in RA. Animal studies and clinical trials agree that treatment with a monoclonal anti-TNFa antibody produces a dramatic clinical remission and a striking response in acute phase reactants. The anti-inflammatory cytokine IL-10 has also been demonstrated to have a dose-dependent ameliorating effect on murine collagen arthritis, acting partly via TNFa inhibition. The major problem with biological treatment of RA is that therapy needs to be delivered continuously during a long time. One way of achieving prolonged and continuous delivery of TNFa inhibitors or IL-10 would be to use gene therapy. The objectives are: 1. To assess the use of adenoviral vectors to transfer cytokine inhibitory molecules in vitro and in the murine collagen arthritis model, 2. To compare the efficacy of gene therapy with that of biological therapy with IL-10 or anti-TNFa antibodies, and 3. To compare intravenous and local (intra-articular) gene transfer by viral vectors in this murine model. If these gene therapeutic cytokine modulation strategies are safe and at least as effective as treatment with anti-TNFa antibodies or IL-10, clinical trials of cytokine modulating gene therapy in patients with early RA will be possible. The Kennedy Institute is a leading research laboratory and has excellent resources for doing the work proposed. They also have much experience with the murine collagen arthritis model, needed to assess in vivo results. A group is
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Politics of Conservation and Unequal Ecological Exchange in European Peripheries' in the context of a Horizon Europe call.

assistant: **Objectives**

GreenFrontier will radically transform understandings of how strict protection of nature remakes human-environment relations in Europe’s marginal areas by developing a novel field of inquiry - political ecology of conservation frontiers. It breaks new grounds from research on frontier commodities by showing that uneven power relations within the EU’s conservation vision create a new resource – wilderness, essential for future green growth. The project’s pioneering and high-risk research design combines approaches from three disciplines –anthropology, history and politics.Its main research question is: How does a green growth vision based on strict protection of biodiversity affect human-environment relations in Europe’s marginal areas?GreenFrontier is urgently required because the EU's visions of green growth, which includes earmarking 10% of the EU’s land area for strict protection by 2030, raise serious issues of social and environmental injustice: involuntary changes to livelihoods, forced displacement, marginalisation and decline of traditional ecological knowledge. The project will investigate how strict protection of nature reshapes socio-environmental relations in the following mountain regions often overlooked by academic debates: the Southern Carpathians in Romania, the Central Apennines in Italy, the Central Cantabrians in Spain, and the Bieszczady in Poland. The project moves beyond the state of the art and explores new analytical frameworks to understand European conservation frontiers within their specific genealogies of land use change and as part of the current political momentum of green growth imperatives within the EU.GreenFrontier challenges the mainstream understanding of commodity frontiers as happening in the global South. Instead, it focuses on ho
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Clinical validation of the DiviTum assay in two high profile clinical studies in Europe'.

assistant: **Innovation**

The traditionally practiced approach to cancer therapy and development of new cancer drugs is to treat a large pool of patients as potential responders. This results in patients not receiving the optimal treatment; payers paying for treatments that do not benefit patients; drug developers facing higher risk of regulatory failure due to not being able to use better tools for selection of patients in the clinical development program; and clinicians lacking predictive and monitoring tools to administer optimal treatment of patients. Our company has developed a state-of-the-art assay kit - DiviTum™, for the serum-based detection of Thymidine Kinase (TK) activity – a key enzyme involved in cell proliferation. There is compelling scientific rationale to use TK as a biomarker for drugs that disrupt cell cycle regulation, such as Cyclin Dependent Kinase (CDK) inhibitors. As part of the previously conducted SME Instrument Phase 1 feasibility study, our company has identified the clinical study & research market segment, comprised of pharma companies that develop CDK inhibitors, as a current target for the commercialization of DiviTum™. Our company has successfully negotiated to be part of two high-profile clinical studies involving a novel CDK inhibitor with leading oncology institutes in Europe. A clinically validated DiviTum™ has the potential to become the gold standard predictive and efficacy biomarker for cell cycle regulating drugs in selected advanced, solid tumors. This will benefit patients through improved utilization of current and novel treatments; payers by saving costs on ineffective treatments; clinicians by providing a critical clinical decision tool; and drug developers by improving clinical trial success rates through optimized cohort selection, shorter time to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The first Integrated m-Health solution for anaphylaxis management.' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Adan Medical Innovation is a private company focused on the medical devices and the m-health solutions markets. We have patented an m-Health technology for anaphylaxis management, which consists on a smart case for an epinephrine auto-injector linked via Bluetooth to a medical mobile app. Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death. The only adequate treatment is an immediate intramuscular epinephrine injection by using an auto-injector. However, patient self-management of auto-injectors has several problems: a) Need to check periodically drug condition, b) low adherence because patients forget carrying the auto-injector, c) difficulties to administer intramuscular epinephrine. Adanmi has developed the first integrated solution to solve all these issues: a) The smart auto-injector case monitors epinephrine condition; b) The smartphone alerts distance from auto-injector in case the subject forgets it, c) during anaphylaxis it initiates an automated emergency protocol alerting contacts with exact GPS location and providing administration video-instructions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Support and networks To Accelerate the construction and Renovation innovation track to market' under Horizon Europe.

assistant: **Concept**

STAR*track aims at expanding the Built4People Innovation Cluster (B4PIC) network developed in the HE project NEBULA and strengthening and supporting B4PICs and their members to deliver sustainable and people-centric innovation and accelerate uptake by regional value and supply chains.This overarching objective will be achieved by:-Integrating new B4PICS: 6 new B4PICs will be set-up in regions so far not covered by the B4PIC network and receive direct support. Outreach activities to innovation clusters will be made in order to reach the B4P contractual target of 10-15 fully mature B4PICs by 2028.-Creating enabling conditions and providing tools and training for B4PICs and their members for increased development and market transfer of sustainable construction and renovation innovation.-Accelerating the demonstration of holistic and inclusive solutions with high market potential through tailored support mechanisms (incl. access to demo sites)-Facilitating access to funding for demonstration, scale-up and implementation of sustainable innovation by local/regional construction value chains-Paving the way for replication, wide-spread use of the supporting tools and services, and continuous expansion of the Built4People network based on a UE27 replication plan with a long-term vision and business model.In order to make B4PICs attractive for different target groups of the innovation value chain, concrete value propositions will be defined to highlight the impact of B4PIC with respect to improvement of innovation capacities and development of sustainable business opportunities.The impact of the B4PIC network and the B4PICs themselves will be measured to show their significance for the green, digital, and people-centric transition of the Built Environment sector, the up-skilling
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Near-zero-index nanophotonic technologies' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Near-zero-index (NZI) media is a family of photonic nanostructures (continuous media and/or metamaterials) characterized by a near-zero refractive index. As the refractive index approaches zero, spatial and temporal variations of the electromagnetic field decouple, giving rise of a regime of qualitatively different light-matter interactions. Therefore, NZI nanostructures exhibit a unique optical response, where a concept as basic as the geometry plays an essentially different role. Examples of the exotic wave phenomena include transmission through deformed waveguides, cavities whose resonant frequency does not depend on the geometry of their external boundary, nonradiating modes in three-dimensional open cavities, violation of effective medium theories, anomalous dispersion, nonperturbative nonlinear optics, to name a few.These unconventional effects have a high potential for technological innovation. However, the crucial challenge of transforming these basic phenomena into practical devices has not yet been addressed. In NZINATECH, we will address this challenge pushing forward the basic theoretical research on NZI media to the stage of NZI nanophotonic technologies. To this end, we have outlined an ambitious research plan that includes the experimental demonstration of NZI devices in different material platforms, including polar dielectrics, doped semiconductors and silicon photonics. This multidisciplinary research plan will combine the fields of NZI media, metamaterials, quantum optics, electron-beam spectroscopy, thermal emission and silicon photonics.Our results will also open new areas of research for NZI media, including nontrivial interactions of NZI optical modes with free-electrons and small quantum systems. Finally, by examining fundamental questions in limi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Pandemics Outbreaks Rationalized: towards a universal therapy to eliminate intracellular pathogens and drug resistance' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

I propose here a research vision that aims to revolutionise the way we cure infections caused by intracellular pathogens, with the aim to find a universal therapy to infectious diseases that will also counteract the development of drug resistance. In PANDORA, I will specifically focus on eradicating human tuberculosis, one of the worst pandemics so far. To do this, I will first probe what are the molecular ‘bar-codes’ of infected cells, namely those specific membrane proteins that cells express upon infection. I will use this to reversely engineer a repertoire of super-selective polymeric nanoparticles - known as Polymersomes - that will carry ligands to recognise, bind, and selectively attack infected cells only, while leaving non-infected cells completely untouched. Such nanocarriers will access the infected cells and locally deliver their payload, which is the core technology of the therapy. Such technology will be inspired by what nature invented: I will reproduce the binding sequence of autolisins, proteins expressed by bacteriophages that specifically bind the wall of Mycobacteria species (the agent causing tuberculosis). I will thus create fusion antibodies (Ab) characterized by (i) the binding sequence of mycobacteriophages autolisins (for selective recognising intracellular Mycobacterial wall) and (ii) an effector region promoting bacterial clearance through either the macrophage-triggered phagocytosis or an ubiquitin-proteasome system. This therapy will represent a complete revolution in the field of new antimicrobial development, as it will combine complete bacterial eradication, development of memory immunity and fight against drug resistance, the three core pillars of this project.The super-selective polymersomes carrying the Abs-based universal therapy wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Closing the gap between design, Engineering and Marketing in the Product Development Process through an Innovation Tool and Design Liaison Coach that Stimulate Team Communication and Creativity' (DEGAP) under Fifth Framework.

assistant: **Objectives**

The aim is to improve the team communication and creativity in multidisciplinary processes in several companies, between designers, marketers and engineers to stimulate synergies among them. These synergies will lead to a better understanding between these disciplines and therefore better-designed new products and services, with improved commercial success. An important role is foreseen for the project development manager who is the link between the project an upper management (board level) of a participating enterprise. Due to the shift of the task of the project leader from organisation to communication, his role will change from a participating foreman to a coach. An innovative tool will stimulate a permanent learning environment for all participating enterprises between multiple disciplines. DEGAP allows to store, exchange and retrieve know-how on a context basis, bringing transparency into the justifications of the development processes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Artificial Intelligence  for Next Generation Energy' (I-NERGY).

assistant: **Concept**

AI spreading in the energy sector is expected to dramatically reshape energy value chain in the next years, by improving business processes performance, while increasing environmental sustainability, strengthening social relationships and propagating high social value among citizens. However, uncertain business cases, fragmented regulations, standards immaturity and low-technical SMEs workforce skills barriers are actually hampering the full exploitation of AI along the energy value chain. I-NERGY will deliver: (i) Financing support through Open Calls to third parties SMEs for new energy use cases and technology building blocks validation, as well as for developing new AI-based energy services, while fully aligning to AI4EU service requirements and strengthening the SME competitiveness on AI for energy; (b) An open modular framework for supporting AI-on-Demand in the energy sector by capitalising on state-of-the-art AI, IoT, semantics, federated learning, analytics tools, which leverage on edge-level AI-based cross-sector multi-stakeholder sovereignty and regulatory preserving interoperable data handling. I-NERGY aims at evolving, scaling up and demonstrating innovative AI-as-a-Service (AIaaS) Energy Analytics Applications and digital twins services that will be validated along 9 pilots, which: (a) Span over the full energy value chain, ranging from optimised management of grid and non-grid RES assets, improved efficiency and reliability of electricity networks operation, optimal risk assessment for energy efficiency investments planning, optimising local and virtual energy communities involvement in flexibility and green energy marketplaces; (b) Delivers other energy and non-energy services to realise synergies among energy commodities (district heating, buildings) and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Protecting and stimulating plurilingual identities in learners in Europe via inclusive policies and classroom practices'.

assistant: **Concept**

The linguistic capital of Europe forms an important part of the EU-identity, yet there are a number of challenges that threaten this capital. In this project, the focus will be on problems that affect and can be effected by education only. The rise of English as lingua franca caused other languages to be pushed to the sidelines, leading to situations where pupils are less or even not motivated to learn other languages besides English even if it concerns an official national language of their country. Although multilingual programs like Content and Language Integrated Learning can affect these attitudes, the large majority of these kind of programs also use English as target language, which does not increase the proficiency in other (foreign) languages. A second threat to the linguistic capital has to do with the protection of heritage languages, where we see that the linguistic capital of EU-citizens more and more includes non-EU languages. In schools, homelanguages are often rejected and usage of them is sometimes even punished, leading pupils who are ashamed of their linguistic capital and have a lower sense of belonging.  The increasing popularity of new technologies like ChatGPT and machine translation also threatens to acquisition of languages, as pupils do not feel the need to learn languages any more. At the same time, these new technologies offer many opportunities for teachers in their classrooms. All these treats can be managed via good evidence-based policies at different governance levels and by ensuring teachers receive sufficient training and inspiration on how to accept and stimulate the linguistic capital of pupils. This will be done in this project via intense collaboration with stakeholders at different levels, to ensure that sustainable guidelines, po