RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'In-Vivo Software Security Analysis at Scale' (2021-2027), addressing dissemination and exploitation.

assistant: **Impact**

Project AT_SCALE will develop the most scalable and reliable techniques for the automatic discovery, diagnosis, and repair of security flaws in software systems to-date. AT_SCALE will make fundamental breakthroughs in empirical methods for reasoning about software systems as they are running in production.Existing scalable techniques for automatic vulnerability discovery and detection provide unreliable results, which limits their utility and threatens the security of our digital world. Static analysis reasons over a model of software executions; it reports too many bugs that do not exist (false positives) and fails to report those that do (false negatives). Fuzzing reasons over artificial executions and thus misses critical security flaws. Statistical claims about the absence of bugs are fundamentally limited to the set of artificial executions.These challenges will be effectively tackled by in-vivo software analysis. Our approach is inspired by the in-vivo approach in biology. A biologist studies complex organisms like we study software systems, either by analyzing a model or under artificial lab conditions. Yet, some behavior is difficult to induce artificially. An in-vivo approach allows us to make empirical statements about properties of a system of arbitrary size within its natural environment. However, unlike in biology, we can clone the entire, running system millions of times per second to run as many concurrent experiments with no impact on the original system.In 2024, the global, annual cost for cybercrime is expected to exceed 10 trillion EUR, highlighting the need for scalable and reliable software security analysis techniques. AT_SCALE will deliver effective technology to fortify Europe’s digital infrastructure against cyberattacks.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Proteolipidomic characterization of the regulatory circuitry of global lipid metabolism' to be submitted under Seventh Framework.

assistant: **Abstract**

The lipidome of eukaryotic cells consists of hundreds to thousands of lipid species that constitute membranes, store metabolic energy and function as bioactive molecules. The physiological importance of lipid complexity is demonstrated by numerous diseases with inherent perturbations of lipid homeostasis including obesity, atherosclerosis, cancer and neurodegenerative disorders. How lipid complexity affects cell homeostasis and how cells regulate lipid metabolism on a lipidome-wide level remain unclear. The regulatory capacity of post-translational modifications in lipid metabolism is scarcely known, but an increasing body of evidence supports the premise that lipid enzyme activity can be dynamically regulated by protein phosphorylation. The main aim of this project is to functionally map the phosphorylation-dependent regulatory network of global lipid metabolism. To this end, we will develop a mass spectrometry-based proteolipidomics strategy for the yeast Saccharomyces cerevisiae. This platform will be designed for parallel quantitative analysis of lipid flux and the phosphorylation state of virtually all lipid enzymes and the kinases, phosphatases, and accessory regulatory factors involved in the cellular signalling networks. S. cerevisiae uses a relatively simple and conserved network of lipid metabolic pathways and is amenable to genetic manipulation and biochemical analyses, which make it a prime model organism for this study. This systems-level approach will enable us to (i) build a comprehensive regulatory map of global lipid metabolic networks, and (ii) delineate the dynamic regulation of lipid metabolism in key cellular events (e.g. cell division). Moreover, this work will help unravel the molecular design of conserved regulatory pathways of lipid metabolism a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'BALTic DYNamics initiative' to be submitted under Fifth Framework.

assistant: **Abstract**

BALTIC DYNAMICS INITIATIVE is proposed to increase the co-operation among innovative SMEs in EU and pre-accession countries. For this purpose several hundred technologies oriented SMEs from the Baltic States will be audited in order to identify their technology and research needs. Partner search in EU and CEEC countries will be carried out for selected firms and face-to-face contacts on the final stage - the Brokerage event - will be established. Through the Baltic Dynamics Help Desk", website and other awareness rising means the companies will be encouraged to participate in the EC RTD activities, CRAFT and other projects. In parallel to the Brokerage event the conference/workshop will bring together representatives from EU and CEEC NCPs, Governmental bodies, Science/Technology parks, Innovation centres and IRCs to discuss the issues and problems of establishing innovation friendly environment in the Baltic region."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'DEVICE FOR LARGE SCALE FOG DECONTAMINATION' (COUNTERFOG) targeting Seventh Framework.

assistant: **Abstract**

COUNTERFOG will be a new, rapid response system for collapsing all kinds of dispersed agents (smoke, fog, spores, etc.) by using a fog made of a solution that could eventually contain any kind of neutralizing component. It will be a permanent installation in large public buildings like railway stations but also a portable COUNTERFOG for use outdoors, used to counteract a CBRN attack in its earliest stages, greatly reducing the number of potential fatalities.  In fact, COUNTERFOG will use the same “weapon” as a CBRN attack: a dispersed state with a large surface/volume ratio. It will penetrate all the intricate holes CBRN agents are able to infiltrate. As it needs a minimum quantity of decontaminant, it is intrinsically an environmental-friendly and electric-compatible system. It would have three benefits: Firstly, to neutralize and collapse the CBRN cloud, secondly, to rapidly decontaminate all the affected people in that area, and finally, to rapidly decontaminate any equipment and the facility itself.Because of the large-scale fogging capacity of up to three components, choice of pressures and capability to simultaneously emulsify liquids and disperse solid particles and an enormous surface/volume ratio, it will be possible to counteract a CBRN cloud in large, open areas.  Nozzle, sensor and solid mesoporous particles will be technological keys.A Fog Dynamic Laboratory will be designed, built and used in the project to test the ability such a system has to condense different kinds of smokes, clouds or fogs and its ability to simultaneously neutralize different kinds of CBRN agents and combined incidents (fire & CBRN). Full scale tests will be also performed. Eventually, the real applicability, side effects and compatibility with conventional fire protection facilities
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Market introduction of a revolutionary innovative cardiac stimulation system for the prevention and termination of post-operative atrial fibrillation' (DefiPace-System).

assistant: **Innovation**

The incidence of cardiac surgeries is increasing world-wide in view of the demographic change. Cardiac surgery carries asignificant amount of risk as on average 60% of patients develop postoperative atrial fibrillation, by far the most frequentlyoccurring complication after cardiac surgery. Clinical investigations show a significant increase in morbidity, mortality andduration of treatment and hospital stay. The risk for stroke is increased 3-fold! From all discussions with renowned surgeonsresults the clear statement that an avoiding or reduction of medical drugs is in any circumstance a preferable and desirableambition. The DefiPace™ system is a proven and awaited method by the physicians treating post-operative patients. Ournew system is unique, as it is the only system in history and today, which allows physicians to prevent and terminate postoperativeatrial fibrillation (POAF) in all patients. It is the only system which combines standard stimulation, bi-atrial pacingas well as epicardial low-energy cardioversion in one hand-held easy-to-use device even on general ward. Target customersare all patients undergoing cardiac surgery world-wide (market volume: € 1.5 billion). Advantages: Simplicity • TMA pacing &cardioversion wires: easy to use, similar to standard pacing wires • DefiPace device: Intuitive handling for clinical staff similarto standard external pacemakers Prevention and Termination: • Bi-atrial pacing as an effective way to prevent POAF •Quick Termination of atrial fibrillation with safe, elegant low energy cardioversion • No anesthesia necessary Cost savingsfor surgical clinics • Significant cost savings: at least €1,000per day/patient Improved health • Few or no medicationrequired • All complications from atrial fibrillation can be completely avoided
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'New and Emerging Risks in Occupational Safety and Health (OSH) - Anticipating and Dealing With Change in the Workplace through Coordination of OSH Risk Research' under Sixth Framework.

assistant: **Concept**

Excellent work environments are required for health of European workforce and the competitiveness of EU. To this end, cohesion, resources, and focus of national research programmes in EU on occupational safety and health (OSH) need to be improved. NEW OSH ERA will bring dynamism to OSH research in Europe by fostering collaboration in OSH research programmes to allow lateral thinking and promote innovations. The Consortium includes 12 leading public agencies, ministries and research organisations funding or managing OSH research in close collaboration with stakeholders from science, economy, and the society. The strategic objective of the NEW OSH ERA is to create a research and innovation market by systematic exchange of information and stepwise integration of research programmes in EU through several instruments improving collaboration between programmes and utilizing electronic databases by evaluation and benchmarking. The goal is to promote cooperation in joint research activities in OSH research. The focus of these programme activities is on: 1) Complex interactions between work environments, work organizations of work and stress factors; 2) New and emerging risks in different industry sectors; 3) Incorporation of innovative approaches in research programme; 4) Developing of broad coalitions to promote sustainable research collaboration.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Sustaining working ability in the nursing profession - investigation of premature departure from work - (NEXT NURSES' EXIT STUDY)' (1998-2002) under Fifth Framework.

assistant: **Objectives**

In most European countries there is a shortage of nursing labour, which will become even more severe in the course of the demographic development. Today' s working conditions do not allow healthy ageing at work for the majority of the nursing staff. The vast majority of nursing staff leaves the nursing profession prior to regular retirement age. Within the framework of cohort studies in 8 European countries, the reasons /circumstances for premature departure from health casework shall be investigated among nursing staff of health care institutions in primary and hospital care. Risk factors and risk groups of premature departure, as well as the subsequent consequences, will be evaluated. So will the factors of relevance for normal ageing. Consequently, the investigation provides the basis for targeted workplace health promotion designed to assure sustainable workability in the nursing profession.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Calabi-Yau varieties and Mori fibre spaces' (2002-2006) targeting Sixth Framework.

assistant: **Abstract**

Algebraic geometry, which roughly speaking studies geometric objects defined by polynomials (called varieties), is one of the largest fields in mathematics today and has wide applications both in technology and physics.Classifying varieties is one of the most important topics in the field and has undergone a major development in the past 20 years. Despite the fact that many new results have been proved, many questions still remain open. The aim of the project is to develop further, generalize and find more applications of a new method recently developed by the researcher and the scientist in charge at the host institution and already applied successfully to certain three-dimensional varieties.The method is based upon reducing classification questions to the study of certain maps on curves in the varieties and works particularly well when the varieties have many'' subvarieties. The project especially aims at finding results for important varieties arising in modern classification theory, such as Mori fiber spaces and Calabi-Yau varieties. The latter constitute a big gap in today's knowledge, because the existing methods are insufficient.At the same time Calabi-Yau varieties play a very important role in modern theoretical physics, so any result on their classification will be of big interest also outside of algebraic geometry. The project will make the researcher increase his research skills on higher dimensional varieties and allow him to collaborate with many experts, both in the area of the project and in many areas complementary to it.As he will coordinate the collaborations and regularly present the latest results in seminars, he will improve both his leading and presentation skills. A further aim is to build the basis for a long time interaction between Norway and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Development of optical concentrators for small PV systems' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Objectives Photovoltaic systems have advantages as sources of small amounts of electrical power in remote areas, but conventional solar panels are expensive. This project aims to reduce the cost of solar electricity by developing small optical systems to concentrate the sunlight onto solar cells to increase their electrical output. A typical unit of 2m2 aperture will give 200-300 watts, enough for household electrification (lights, radio and television) for a farm, school or a few houses, or for small scale water pumping. It should be possible to make concentrator systems at half the cost of current planar solar panels. Technical Approach Many concentrators have been developed in the past, but they have usually been as expensive as conventional solar panels, because concentrator solar cells have cost much more than one-sun cells, and the optical and tracking systems have been expensive. Recent developments, such as BP Solar's laser-grooved buried-grid cells, have made it possible to manufacture solar cells, little different in design and cost from one-sun cells, that can be used at concentration ratios up to 40x. Using these cells with minimum-specification optical and tracking systems, there is considerable scope for cost reduction. The collaborators, Reading University, Universidad Politechnica de Madrid, and ZSW, Stuttgart will examine a wide range of possible concentrators, from fixed non-imaging systems with concentration ratios of 2 or 3x, which are expensive in cells but cheap in structure, through cylindrical lens and mirror systems with concentration ratios of 10 to 20x and single axis tracking, to spherical lens systems with concentration ratios around 40x that require two axis trackers. For each system, performance will be estimated using computer ray-tracing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Functional characterization of the cell division inhibitor MipZ' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Correct positioning of the division plane is essential for the generation of normal offspring. In Caulobacter crescentus, the spatiotemporal control of cell division is mediated by MipZ, a conserved P-loop ATPase forming bipolar gradients with a concentration minimum at the cell centre. Antagonizing the polymerization of the essential divisome component FtsZ, MipZ inhibits divisome assembly near the poles, thereby limiting cytokinesis to midcell. Gradient formation involves a dynamic localization cycle, in which freely diffusible MipZ monomers interact with polar complexes of the centromere-binding protein ParB and then dimerize in an ATP-dependent manner. Dimers dissociate from ParB and are immobilized within the cell through non-specific interaction with chromosomal DNA. Spontaneous ATP hydrolysis triggers disassembly of the complex, releasing MipZ monomers that are recaptured by ParB. How ParB stimulates dimer formation and how DNA-bound dimers inhibit FtsZ assembly is still unknown. We will address these questions by characterizing previously isolated MipZ mutants with FtsZ/ParB interaction defects, using a combination of fluorescence microscopy, two-hybrid analysis, biochemistry, and biophysical techniques such as surface plasmon resonance, microscale thermophoresis or hydrogen-deuterium-exchange mass spectrometry. We will also use synthetic biological and modelling approaches to rebuild the system in a simplistic form to thus gain in-depth knowledge of the function of the different elements.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Acute Inflammation Resolution by Soluble Human Inhibitory Protein', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Acute inflammatory processes are associated with infections as well as autoimmune flares at the basis of a variety of human diseases. While the molecular components and the logic of pro-inflammatory program are relatively well understood, less is known about the molecular mechanism of resolution, governing the termination of inflammatory responses. In the course of carrying out the i-FIVE ERC grant project plan, we identified a novel, secreted, soluble enzyme as a negative regulator of pro-inflammatory immunity receptors. Here we propose a defined and focused set of measures aimed at obtaining solid evidence for therapeutic feasibility of this novel biological agent in resolving inflammatory processes as well as for the securing of intellectual property. The AIRSHIP workplan proposes to obtain enough purified, soluble, endotoxin-free, active and glycosylated protein material to execute two critical tests, one monitoring the inflammatory response in human cells, and one addressing beneficiary effects in a lung murine infection model. Armed with such a successful proof of concept package and having strategically positioned and secured our intellectual property rights we would be determined to embark into an ambitious commercialization initiative.""