RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Harnessing the electric potential of cable bacteria to generate electricity sustainably', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Cable bacteria are centimetre-long, filamentous, multicellular bacteria present ubiquitously in freshwater and marine sediments, and participate in long-distance electron transfer by coupling the oxidation of sulphide in anoxic sediment to the reduction of oxygen. Cable bacteria possess an internal electric grid, enabling them to transport electrons over centimeter-scale distances. This project proposes the cultivation of cable bacteria on electrodes to harness their potential to generate electricity. Further, the development of a switchable bioelectrochemical system altering between electrogenesis and electrotrophy is proposed. Such a device would enable biological power generation and energy storage in a single device, and will be tested to power a microprocessor biologically, enabling development of biodegradable electronics. These experiments would be performed in specialized bioelectrochemical systems by varying the applied potential from positive to negative to induce the switch. Electrochemical interactions of cable bacteria with electrodes will be monitored by amperometry, voltammetry, and impedance spectroscopy. The cables will be integrated into a power management system consisting of a microprocessor chip, a current and voltage-measuring circuitry and a microcontroller to power the microprocessor with electrons obtained from the sediment. Finally, the physiological possibility of dark oxygen generation by cable bacteria in anaerobic sediments will also be explored, that would enable the use of cables as intermediates to convert any aerobic microbe into an electrogen. This mechanism will potentially uncover an unknown mode of oxygen production and usher in a completely new understanding of oxygen transport through the oxic-anoxic interface.  The project bridge
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Understanding chronic pain and new druggable targets: Focus on glial-opioid receptor interface'.

assistant: **Concept**

Chronic pain is prevalent and it causes decreased quality of life and significant costs to the society in terms of lost working capacity. Currently available analgesics are either not effective enough or patients cannot take them due to adverse effects. Non-steroidal anti-inflammatory drugs are a major cause of drug-related morbidity and mortality. Opioids can cause tolerance and addiction when used for long-term management of chronic pain. Analgesic efficacy can be improved by targeting specific mechanisms that are involved in pain processing of specific conditions, e.g. fibromyalgia, osteoarthritis, rheumatoid arthritis, and neuropathic pain, and by improving the safety profile of the current analgesics. This project focuses on the role of glial activation by tissue and nerve injury, inflammation, and opioids in large cohorts of chronic pain patients. We will develop a biomarker profile for the clinical conditions by assessing inflammatory markers in cerebrospinal fluid and glial activation in the brain with PET, by performing well-validated experimental pain tests, and genetics. Interindividual differences in pain perception will be studied using experimental pain tests including activation of descending inhibitions as a biomarker of endogenous analgesia and fMRI. Individual differences with the glial activation and pain perception will be used to design different research lines across the board aiming at developing personalized treatments for pain. We will use well-validated animal models relevant for arthritis, fibromyalgia, and neuropathic pain. Glial activation in these animal models will be studied using novel methodology to better understand the pathophysiology of these conditions. They will also be used as targets for new drug discovery which will focus on the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Quantum control of levitated nanoparticles' (QUCLN).

assistant: **Concept**

Coherent control of a macroscopic quantum system is one of the main objectives of the field of optomechanics with potentially game changing implications for fundamental physics as well as technology. On one side it could allow the exploration of the classical-to-quantum boundary, on the other it could allow the development of quantum limited sensors and provide a fundamental building block for quantum information.  Among the rich variety of systems in the optomechanics field of research, levitated nanoparticles offer the unique and appealing feature of being highly decupled from the environment allowing the observation of extremely high quality factors. Cavity cooling in high vacuum of a trapped nanoparticle down to its motional quantum ground state is potentially achievable at room temperatures. By combining an optical and electrodynamic trapping potential, the Host Group has already demonstrated cooling to a phonon number of the order of ~300 so that ground state cooling is within reach. The QUCLN project aims to bring the levitated nanoparticle platform in the quantum regime by generating non-classical states for the mechanical degrees of freedom such as squeezed and Fock states. Such results would represent a major breakthrough in the field of optomechanics and quantum technologies in general, which have been included as a Future and Emerging technology in the Horizon 2020 work programme. More importantly, it would represent a significant step toward tests of collapse models and the experimental exploration of the role of gravity in quantum mechanics. Indeed, this is the underlying long term motivation of the project.The combination of the host group leading position in the field and the proven track record of high level scientific research of the experienced resear
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Ecological and evolutionary constraints on the temperature dependence of the carbon cycle' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The cycling of carbon between the biosphere and the atmosphere is mediated by its transformation and flux through ecosystems. Atmospheric CO2 is fixed by photosynthesis, exchanged between organisms via their interactions, and re-emitted to the atmosphere through the by-products of their metabolism (CO2). These metabolic processes are inherently temperature dependent, and consequently there is potential for elevated rates of respiration (CO2 production) in a warmer world to further accelerate global warming. However, large uncertainties about the magnitude of any response exist, owing to limited understanding of the mechanisms underpinning the temperature dependence of ecosystem metabolism. I approach this problem from a new perspective, by proposing that interactions between evolutionary processes, which influence the frequency and variance of metabolic traits within populations, and ecological interactions between populations, which shape the structure and dynamics of communities, constrain the overall temperature dependence of metabolic fluxes at the ecosystem-level. I will ask: How do differences in thermal responses and the nature of ecological interactions between species influence the temperature response of an ecosystem? What is the rate and magnitude of thermal adaptation? Does coevolution in a community affect thermal adaptation? How do differences in thermal responses and turnover in species composition affect the temperature dependence of ecosystems? I will answer these questions with an array of experiments that recombine microbes isolated from a long-term freshwater warming experiment (+4°C for 10 years) in communities in the laboratory. This project will break new ground in understanding how patterns and processes at the ecosystem-level emerge from the dyn
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'New extraction process for phytoprotectants from ecologic cultivation of fruits and vegetables' (1998-2002) under Fifth Framework.

assistant: **Objectives**

To give producers of organically-grown fruit and vegetable the chance to increase their value added margin tenfold for a part of their raw products and to provide the European consumer with foods with preventive medicinal properties, the following project goals are to be pursued. To investigate and develop the technical, process-related general conditions for a new process for producing phytoprotectants directly at the site of the fruit and vegetable producer's. To investigate and develop primary products that make use of these phytoprotectants, e.g. in nutraceuticals, taking particular account of the nutritional and health needs of the European consumer.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Electronic Tendering, Bidding, and Negotiation Real Time System' (E-NTRY), addressing dissemination and exploitation.

assistant: **Impact**

The objective of PICK is to develop two innovative methods and tools for effective management of corporate knowledge needed to support main process improvement (PI) steps, specifically for manufacturing processes. The methods and tools will be tested within the industrial environments of three large automotive and aerospace companies under real conditions. PICK will solve several fundamental technical problems, the most challenging being the one related to the development of an innovative system for unique knowledge management which can be used for different PI related tasks, both in planning and execution phase. PICK will also contribute to standardisation of interfaces needed for capturing knowledge from different systems.The technological objective is to develop two innovative methods and tools for the effective management of corporate knowledge needed to support the main process improvement (PI) steps, specifically for manufacturing processes. The business objectives are to achieve direct benefits for the end-users based on the application of PICK methods and tools in terms of: reduction of effort/costs for PI tasks, planning/execution of changes in processes (especially in run-up phases of the re-designed process), reduction of risks when changes in processes/products are done, e.g. reduction of potential wastes and re-work, down times of machines and workers etc. The application of PICK results will improve the possibilities to involve all employees in PI tasks, to easier transfer/share knowledge between manufacturing areas/lines, or between different plants.Work description:This Project will design, develop, pilot, evaluate an innovative Internet-based E-Commerce platform (E-NTRY) enabling more open, transparent, fair and, at the same time, more efficient and mor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Feasibility study for scaling UP thermal conversion technology that turns scrap TYREs into high quality resources' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

UP-TYRE project proposes an environmentally friendly, efficient and profitable solution for converting scrap tyres into high quality products, such as light heating oil used in heat and power generation. State-of-the-art alternative technologies, for instance tyre pyrolysis, are energy-intensive, costly and yield little varieties of low value products. The thermal conversion reactor proposed by Meratel allows converting tyres into high yield of high quality products without generating additional waste or pollution, while redefining scrap tyres from a costly problem to a valuable resource for tyre management companies. The proposed thermal conversion technology has significant advantages that translate into over 40% cost saving for heat and power plants across Europe when substituting regular fossil fuels with the proposed tyre-derived light heating oil. The European market for light heating oil is substantial in size and looking for alternatives to reduce reliance on fossil fuels. Coupled with stable supply of scrap tyres and environmentally friendly processing method, the proposed technology has ample commercial potential.The proposed technology has already been demonstrated in relevant environment on a small scale, but it is necessary to fully estimate the commercial feasibility of the method to ensure the best possible strategy for a successful commercialization. The work planned in Phase 1 will cover all the aspects regarding this objective: a detailed business plan creation, IPR study, and the final technology configuration to enable scale-up of the proposed technology. The overall objective of the innovation project is scaling up the proposed technology on a European scale. Before this can be done, an appropriate automation and control system needs to be developed
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'New processing system for pre-cast concrete pipes production' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

Aim of the presented project is the development of a new concrete processing system aimed at the construction of pre-cast concrete pipes of small/medium diameter, specially used in sewage systems. The proposed system will produce more resistant and longer life concrete pipes by the development of a new mechanical chuck able of a forced conduction of concrete, managed by a control system able to determine the chuck speed and the concrete application area depending on a real - time quality control of the pipe under production. The system will produce great benefits by an environmental point of view, reducing the infiltration and pipes risk of breaks, and will address the users need of pipes which require less maintenance.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Targeting cell migration in chronmic inflammation'.

assistant: **Objectives**

Chronic inflammation is a systemic disorder resulting from the deregulation of multiple, mechanistically unrelated higher order biological processes. This Consortium will promote the integration of multi-disciplinary research groups to achieve a thorough understanding of directed inflammatory cell migration towards and across injured tissues. To achieve its goals, the MAIN Consortium will be based on four developmental Research Programs (Tool Development Program, Target Identification Program, Target Validation Program and Drug Development Program), three Support Facilities (Imaging, Polemics and Micro arrays) and one Core Facility (Bio informatics). The Research Programs are tightly interconnected in a logical sequence of highly integrated activities. The Tool Development Program (TDI) will develop technological tools that are instrumental to make advancements in the field of cell migration. The Target Identification Program (TIP) will identify signalling pathways and/or molecular networks involved in defined aspects of inflammatory cell migration. The Target Validation Program (TVP) will validate targets emerging from the TIP by testing them across in vitro and in vivo models, different inducing stimuli and manipulating conditions. The TVP combines the products of the TOP and the TIP to provide a unified explanation on how multiple inputs" received by inflammatory cells result in spatially and temporally coordinated "outputs", affecting the migratory behaviour of such cells. The Drug Development Program (DDP) will transfer selected targets into a pipeline of drug development, through the Sees of the Consortium. The Support Facilities (Imaging, Micro arrays and Polemics) and the Bio informatics Core will provide technological and bio computational support to the progra
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Metabolic effects of Endocrine Disrupting Chemicals: novel testing METhods and adverse outcome pathways' under Horizon 2020.

assistant: **Concept**

Endocrine disruptors (EDs) are defined as exogenous chemicals that alter functions of the endocrine system, thereby causing adverse health effects in an organism or its progeny. Historically, the field of ED research has focused on reproductive endocrinology and related hormones, which is reflected in the regulatory test methods assessing endocrine effects of xenobiotics. However, recent evidence links increased incidence of metabolic syndrome (a cluster of metabolic risk factors including abdominal obesity, dyslipidemia, elevated blood pressure, and elevated fasting glucose) to EDs, increasing the incidence of atherosclerosis and type 2 diabetes. Despite these findings, adequate testing methods for metabolic effects of EDs are lacking. The project “Metabolic effects of Endocrine Disrupting Chemicals: novel testing METhods and adverse outcome pathways” (EDCMET) brings together experts in various research fields, including systems toxicologists, experimental biologists with a thorough understanding of the molecular mechanisms of metabolic disease and comprehensive in vitro and in vivo methodological skills and ultimately, epidemiologists linking environmental exposure to adverse metabolic outcomes. This proposal focuses on developing novel test methods and models to assess the metabolic effects of EDs. Combined in silico methods, in vitro and in vivo methods are developed with an emphasis on liver and adipose tissue and endocrine pathways related to their metabolism. In addition, epidemiological and field monitoring data is used to gain information regarding the exposure to chemicals and ED-related metabolic effects. The interdisciplinary approach and complementary expertise of the participants will identify novel mechanisms of action, and in collaboration with the Europ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'UNDERSTANDING THE NATURE OF FACE PERCEPTION: NEW INSIGHTS FROM STEADY-STATE VISUAL EVOKED POTENTIALS'.

assistant: **Objectives**

Face recognition is one of the most complex functions of the human mind/brain, so that no artificial device can surpass human abilities in this function. The goal of this project is to understand a fundamental aspect of face recognition, individual face perception: how, from sensory information, does the human mind/brain build a visual representation of a particular face? To clarify this question, I will introduce the method of steady-state visual evoked potentials (SSVEPs) in the field of face perception. This approach has never been applied to face perception, but we recently started using it and collected strong data demonstrating the feasibility of the approach. It is based on the repetitive stimulation of the visual system at a fixed frequency rate, and the recording on the human scalp of an electrical response (electroencephalogram, EEG) that oscillates at that specific frequency rate. Because of its extremely high signal-to-noise ratio and its non-ambiguity with respect to the measurement of the signal of interest, this method is ideal to assess the human brain’s sensitivity to facial identity, non-invasively, and with the exact same approach in normal adults, infants and children, as well as clinical populations. SSVEP will also allow “tagging” different features of a stimulus with different stimulation frequencies (“frequency-tagging” method), and thus measure the representation and processing of these features independently, as well as their potential integration. Overall, this proposal should shed light on understanding one of the most complex function of the human mind/brain, while its realization will undoubtedly generate relevant data and paradigms useful for understanding other aspects of face processing (e.g., perception of facial expression) and high-le