RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Multimedia Authoring Environments for Children' (MATCH).

assistant: **Concept**

The main objective of the project is to develop a multimedia authoring tool for children. A direct result of this research effort will be to establish a communication channel between the student, the teacher and the developer that will eventually lead to their active involvement as designers and users.More specifically, the project will deliver : - MATCh, a multimedia authoring tool especially designed for children;- three multimedia applications developed with MATCh, that will serve as system testbeds;- user manual and accompanying system documentation;- a report on how children adapt to the usage of new technologies.The Incremental Prototyping methodology will be used for system development. One prototype version of the system will be delivered in order to refine initial specifications by developing three multimedia applications; then the final system version will be implemented.To further enhance the initial research and development efforts the features of the existing Logo-like environment will be extended to incorporate the following additional features:Multimedia Authoring for children: many facilities which will enable children to use multimedia resources and develop application using visual and drag and drop facilities (e.g., sound, music, image, story editors, etc.).WWW Authoring for children: facilities which will enable children to navigate the Internet and develop WWW pages.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Preventing explosions: Resolved measurement of turbulent flow electrification' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

"Please research electrostatic charging,"" pleaded the R&D leader of a major chemical company. While other ignition sources for explosions can be detected, seen, or smelled, electrostatic charge appears unexpectedly whenever liquids or solids flow. Responding to the urgent need for reliable detection of electrostatic charge, we propose advancing the MefiX flow charge measurement system, a groundbreaking innovation from the ERC project PowFEct, to the proof-of-concept stage.MefiX represents a paradigm shift in safety management, offering the worlds first system capable of measuring turbulent flow charge in situ and with spatial resolution. Leveraging advanced machine learning techniques, MefiX identifies hidden ignition sources, providing early warnings against dangerous increases in electrostatic charge during liquid or powder transport processes. The primary technical objective of this PoC is to transition MefiX from a laboratory experiment to a functional prototype. We will validate its technical feasibility under real-world operating conditions and develop a compact, automated, cost-effective prototype device.Our business development activities will assess the projects commercial viability, supported by secured patents and engagement with European and international stakeholders. To attract customers and investors, we will showcase MefiX at trade fairs and establish a comprehensive roadmap for its future commercialization. Guided by an advisory board comprising multidisciplinary experts, we aim to bridge the gap between scientific excellence and commercial success, foster safe workplaces, and contribute to a prosperous society.Given the immense value of industrial plants, it is highly profitable for companies to invest in MefiX. With quantifiable benefits regarding sa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Oral bio-lubrication and bio-adsorption from multi-phased complex fluids' (BIOLUBRICATION).

assistant: **Innovation**

There is a considerable rise in obesity within Europe which is driving a consumer need for processed food and beverages that have health and vitality benefits. Food companies are under increasing pressure to significantly reduce sugar, fat and salt levels, as well as formulate products that target specific consumer groups for nutritional efficacy. However, the replacement of such ingredients with healthier alternatives, or inclusion of benefit agents, typically renders a product unacceptable to consumers due to mouth feel and taste considerations.The physical origin of mouth feel and taste is from the dynamic response of products between oral biosurfaces. During oral processing, such products which are typically multi-phased complex fluids and soft solids are sheared and compressed, while various components may deposit onto oral surfaces and/or disrupt salivary films. At the same time, saliva is secreted into the oral cavity for mixing and reacting with the food/beverage. The resulting product is confined to very thin films between soft rubbing surfaces (i.e. the tongue and palate), which determines oral lubricity and thus mouthfeel and textural attributes of food, as well as mass transport of tastants to receptors on the tongue and aromas to olfactory receptors in the nose.The development of techniques to characterise the dynamic behaviour of complex fluids under confinement in response to this environment will lead to the ability to create new design rules for controlling the sensorial response of consumer products with healthier compositions, enabling enhancement of quality and nutritional value. To achieve this we require the combination of world leading expertise in surface science and oral protein chemistry from the YKI Institute of Surface Chemistry with the expe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Specific immune defense of humans and animals' (1998-2002), addressing dissemination and exploitation.

assistant: **Impact**

Postgraduate and PhD students ( veterinarians, molecular biologists and immunologists) are invited to apply for a 10 - 12 months research fellowship in Immunology. The fellowship is on cellular immunology and animal or human diseases (and experimental models). It contains theoretical courses on immunology, vaccines and immunogenetics, attendance of seminars on immunology and participation in the current research programs of the department and in house training in all technologies of cellular and molecular immunology. These technologies comprise: T cell culture and cloning, T cell proliferation and cytolysis assays, in vivo animal experimentation (rat and mouse ), FACS analysis and sorting, intracellular cytokine stainings, PCR cloning, peptide synthesis, analysis of antigen specific T cells with MHC-peptide multimers, production of hybridomas and monoclonal antibodies, protein expression and purification, MHC typing. The research performed will be in one of the following areas:a. The T lymphocyte as the regulator of the immune response (vaccines and immunotherapies of infection, cancer and autoimmune diseases);b. Identification and functional characterization of MHC molecules and other membrane molecules in the immune response;c. Immunopathogenesis and immuno modulation of various diseases in cattle, horses and companion animals. All activities in the department are English spoken. The application with the curriculum vitae, main fields of scientific interest, technical abilities and reason for the application and a letter of support from the Department Director has to be sent to Prof. Dr. W. van Eden or Dr. V.P.M.G. Rutten, Department of Infectious Diseases and Immunology, Division of Immunology, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL Ut
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'A novel packaging system for meat safety and shelf-life extension' under Seventh Framework.

assistant: **Concept**

Meat and poultry products are vehicles for millions of cases of foodborne illness globally each year. Controlling pathogens such as campylobacter, Escherichia coli O157:H7, Listeria monocytogenes, Salmonella, and Yersinia enterocolitica, is a primary goal for industry. Additionally, processors are constantly striving to lengthen product shelf life. However, consumer aversion to traditional chemical preservatives has left processors with less flexibility in choosing preservation methods. This has opened up a technological gap where process innovation is required and a major business opportunity presents itself for the development of a non-thermal, novel food preservation system to control foodborne pathogens associated with meat and poultry.This project will develop a continuous in-package decontamination and shelf-life extension system for meat based on Non-thermal plasma (NTP), offering antimicrobial efficacy without the use of chemical sanitizers and which is non-invasive, leaves zero residues and does not adversely affect product quality. Preliminary studies with NPT on meat products, point to rapid inactivation of pathogenic and spoilage microorganisms associated with meat, resulting in significant extensions of shelf-life (an additional 5 days). A laboratory test-rig system will be optimised for its antimicrobial efficacy for in-package decontamination of both red and white meats. Shelf life extension, along with organoleptic and nutritional properties of treated meat will be evaluated. The results will then be scaled up to pre-commercial level and validated in the industry paving the way forward for rapid post-project industrialisation.A critical advantage of this world-first technology for the meat industry is the In-package treatment, which is desired by the foo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'TRANSPORTATION WHEELCHAIR WITH HIGH IMPACT SAFETY AND ADVANCED SENSOR COMFORTABILITY FOR PEOPLE WITH MOBILITY PROBLEMS' (TRANSWHEEL).

assistant: **Concept**

Mobility-impaired individuals can rarely use a wheelchair all the way from home to the place of work or recreation and back again. TRANSWHEEL targets three aspects of wheelchair development: transport safety, comfort, and adaptability. A CAD/CAM redesign will produce a light-weight transportable wheelchair capable of ensuring the same safety as a seat in standard transport, with enhanced manoeuvrability allowing the user to adjust its height and position to perform routine tasks while travelling (store luggage, open the window, use a train table, etc.). A vehicle seat will also be developed, to address the needs of people with lower limb and torso disabilities not using a wheelchair. A prototype wheelchair and car seat will be developed, for use in both laboratory and user trials, and design guidelines and a code of good practice will be widely disseminated.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Artificial recharge demonstration project' in the context of a Fifth Framework call.

assistant: **Objectives**

The term Artificial Recharge (AR) covers a range of technologies that typically utilise the natural cleaning capacity of natural subsoil systems to produce drinking water from surface water. This project will contribute to achievement of the overall objective by demonstrating a management tool that uses sophisticated monitoring systems linking automatic real-time data acquisition and available on-line sensor systems and fast field analysis kits with intelligent decision support software, which compile and communicate digested data to action protocol. The increased surveillance will be combined with development and implementation of operations schemes that will decrease the risk of contaminated drinking water and at the same time ensures a stable water production
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Deciphering the mechanism of cellular aging: interaction of oxidatively damaged proteins with the cellular membranes' (CarboPore), addressing dissemination and exploitation.

assistant: **Impact**

Aging is one of the greatest mysteries in biology and a considerable contemporary societal challenge. Despite extensive research, the etiology of aging remains poorly understood. Most current theories focus on DNA damage as the root cause of aging. However, this view has been challenged by discovery that oxidative damage to proteins alone is sufficient to recapitulate molecular and cellular hallmarks of aging. In this project, we aim to elucidate the mechanism through which oxidatively damaged/carbonylated proteins lead to age-associated cellular dysfunction. Since misfolded, oxidatively damaged proteins form aggregates, and protein aggregates contribute to aging of various tissues, as well as lead to damage of cellular membranes, we hypothesize that age-associated increase in oxidative damage to proteins binding of the resulting protein aggregates to cellular membranes lead to membrane damage and permeabilization. To test this hypothesis, we will characterize oxidatively damaged oligomers and aggregates and assess their association with cellular membranes. Membrane damage will be evaluated upon its exposure to oxidized oligomers in vitro, using artificial lipid vesicles, and in living bacterial and mammalian cells. Interdisciplinary approaches will be used, including advanced imaging techniques such as atomic force microscopy, stimulated emission depletion microscopy and Fourier transform infrared microscopy and spectroscopy, mass spectrometry and various biochemical techniques. During the fellowship, the applicant will acquire skills necessary for reaching a leading independent position, basic entrepreneurial experience and will be given an opportunity to promptly commercialize her research. Moreover, the fellowship will lead to creation of several new sustainable int
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Modelling Sound Generation and Propagation in Fluid Machinery Systems' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Fluid machines are a familiar part of everyday life in the home, the workplace and in transportation systems. Virtually all fluid machinery generates sound, and some examplessuch as motor cycle and aircraft jet enginesare notorious for their noise output. It is hard to identify any day to day human activity in which individuals are not exposed to fluid machinery noise. For instance in the BRITE EURAM project no. 5983 (EQUIP), fans, where flow is the main cause of noise generation, have been identified as one of the most important noise sources in machines. Another important aerodynamic source process is regenerated noise in flow ducts, which imposes a major limitation for the performance of compact flow systems. In improving the performance there is also a tendency to increase flow velocities in fluid machines, which increases the importance of flow generated noise. Increased flow velocities also change the sound transmission properties of flow ducts in machines. Overall, the physics of sound generation and transmission in fluid machinery systems is not well understood. The state of the art in the acoustics of fluid machinery falls far short of the requirement for well developed and comprehensive predictive methods, that can be used for a better acoustical design of these devices. Even physical modeling of the passive components in the ductwork of fluid machines is limited mainly to relatively simple systems, and the understanding of source mechanisms and complex flow/acoustic interaction phenomena is only barely adequate in a limited number of cases. The major innovative aspects of this project are new or improved prediction models with the following important applications: * source descriptions for IC engines * design of fans for minimum noise production in non ideal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'First time ultra-sensitive and simultaneous quantification of proteins, interactions, and post-translational modifications in single cells to enable exponential growth in proteomics and interactomics'.

assistant: **Concept**

In a human cell there are about 20k protein coding genes (genome) that originate ~100k proteins (proteome). Proteins are involved in complex networks of protein-protein interactions (PPIs) influenced by post-translational modifications (PTMs), the interactome of living cells (~800,000 entities). The genome is mostly static throughout cell lifetime and can be sequenced today in <1h. The proteome and interactome are changing with e.g., environment and health, and not yet fully known. Today's methods for proteomics and interactomics are tedious, and lack sensitivity, quantitativity and parallelism.PICO-NGS combines ultra-high sensitivity (>10 fM) with high parallelism measuring proteins, PPIs, and PTMs simultaneously (>50 targets). This will disrupt the global proteomics market (€29 B worth, 16% CAGR). This will fertilise ground-breaking academic research and accelerate developments in e.g., Pharma (drug discovery), Biotech (biomarkers/diagnosis), and Agrotech (crop sciences) industries.


**Keywords:** Proteomics,DNA identifiers,Next-generation sequencing,Biological pathways,Immunoassays,Posttranslational modification of proteins,Interactomics,Digital assays
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Climate Shocks and Subjective Wellbeing in Small Island Developing States: Implications for Subnational Foreign Aid' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Subjective well-being (SWB) is gaining recognition as a key indicator of societal progress, yet it is often overlooked in assessments of the impacts of climate shocks, which are increasing in both severity and frequency. This research, CLIMWELB, aims to fill this gap by pursuing three specific research objectives: 1) examining the impact of climate shocks—drought, flooding, and extreme temperatures—on SWB, 2) investigating the mechanisms through which these shocks affect SWB, and 3) exploring the role of subnational foreign aid in mitigating the potential adverse effects of climate shocks on SWB. CLIMWELB will focus on Small Island Developing States (SIDS), which rank among the most vulnerable globally to climate shocks and receive disproportionately higher levels of foreign aid relative to their economies. To achieve the specific research objectives, CLIMWELB will employ quasi-experimental methods, machine learning techniques, and a suite of robustness checks. Geocoded data on climate shocks and subnational foreign aid will be extracted from the European Centre for Medium-Range Weather Forecasts (ECMWF) and AidData project databases, respectively, while geocoded household data will be drawn from the Demographic and Health Surveys (DHS), the World Bank Microdata Library, and the Afrobarometer database. CLIMWELB will shape scientific discourse by providing the first evidence of the impact of climate shocks on SWB in vulnerable contexts such as SIDS, and offer pioneering insights into the role of subnational aid as a mitigating factor. In addition, CLIMWELB's findings will interest various stakeholders—including SIDS governments, foreign aid donors, international organizations (UN and EU agencies), NGOs, and international financial institutions (World Bank)—and inform the