RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Photonic Interconnect Layer on CMOS by Wafer-Scale Integration'.

assistant: **Concept**

For future generation electronic circuits a severe bottleneck is expected on the global interconnect level. One of the most promising solutions is the use of an optical interconnect layer. Therefore, PICMOS will demonstrate the feasibility of adding a photonic interconnect layer on top of silicon ICs. This interconnect layer will be fabricated by a combination of wafer bonding and wafer-scale processing steps. It will be planar and will be built from a high-density passive optical wiring circuit integrated with InP-based sources and detectors using a wafer bonding approach.Two different integration strategies will be investigated: a wafer-to-wafer bond technology where the photonic interconnect layer is fabricated in parallel with the electronic circuits wafer and where both wafers are subsequently bonded together and an above-IC approach where the interconnect layer is fabricated directly on top of the electronic circuits. For the first approach, SOI-waveguides allowing for very high-density wiring will be developed. For the above-IC approach, an innovative type of high-contrast polymer waveguides compatible with CMOS back-end processing will be developed. Both types of waveguides will be fabricated using standard CMOS-processing techniques.The III-V epi material for the active photonic devices will be bonded on top of the waveguide circuits and the substrate will be removed. The active devices will be defined in the remaining membrane. In all fabrication steps, only waferscale technologies will be employed with the only exception made for the bonding of the III-V semiconductor material. Because of the large size difference between silicon and InP wafers and the limited space occupied by the active photonic devices, a rapid die-to-wafer bonding step will be developed f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'ENZYMATIC RECYCLING OF WASTE COOKING OILS FOR THE PLASTIC INDUSTRY'.

assistant: **Innovation**

The development of synthetic plastics has changed our world and currently several types of plastics are found in different applications. Most of the plastics comes from fossil resources and they are non-biodegradable materials causing a serious threat for the environment. Bioplastics are mostly produced from food resources which are not sustainable. For these reasons, the solution can be the use of waste. REWIND aims at the valorization of waste products through their enzymatic transformation following a circular economy approach. The production of monomers and polymers will be capitalized through the test of different recombinantly produced enzymes. The enzymatic transformations will be tested using single enzymes or a cocktail of biocatalysts (either free or immobilized) to identify the potential of the biocatalytic cascade. The use of enzymes, and their further engineering, will reduce the utilization of harsh reaction conditions and chemicals, such as organic solvents and metal catalysts. The produced bioplastics will be tested in terms of thermal and mechanical properties. In order to test their sustainability and impact on the environment, degradation tests in the presence of different environmental conditions (pH, Temperature and pressure) and with biological factors (enzymes and microorganisms) will be assayed. Sustainability assessment of the process and the products’ life will identify the steps that could be improved to reduce the impact. The researcher, who already possesses sound knowledge and skills in biocatalysis, will gain more knowledge in polymer chemistry and material characterization through the attendance of hand-on courses and collaborations with polymer chemists. Entrepreneurship and patent writing courses will increase the innovative mindset of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Methodology for local and regional real estate markets analyses and possible applications of results' (2002-2006) targeting Sixth Framework.

assistant: **Abstract**

The level of development in real estate market affects the economic and social spheres. It isdependent on different economic, social, legal and even political conditions. The real estatemarket is primarily of local and regional nature in the housing and a part of commercialsector. The methodology for analysis that has been worked out in the EU countries allowsfor demand anticipation and indication of the supply adapting abilities. Among other things itmeans lowering the threat of too rapid increase follo wed by deep crisis because the verymechanism and certain warning signals are known. Thus, it is possible to assign remedialmeasures.Co-operation with experienced EU scientists will facilitate the development of modernmethodology for local and regional real estate markets analysis. It will also assist inbroadening the course and teaching offer of the Department. Representing a similar field ofinterests UE research and scientific units carry out comprehensive scientific researches with aparticular focus on re cognition of local and regional market characteristics (subjects ofresearch include living preferences among various age groups, construction sector activity,financial sector activity in relation to credit and mortgage loans execution).Getting to know the methodology would help to work out our own research methods.It would help begin the study on the local and regional market, which, in the longer term andupon the receipt of historical data sequence, should help identify the tendencies and marketmechanisms. The research could be used to develop real estate monitoring in a joint effortwith statistical institutionsKnowledge transfer is indispensable for carrying out the project objective. In this caseknowledge transfer should involve inviting experienced EU sc ientists
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Physiological and Rehabilitation Outcomes: Gains from Automated Interventions in stroke Therapy (PRO GAIT)' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Developments in robotics allow people with profound neuromuscular deficits after stroke to walk with assistance (during the gait cycle) using an exoskeleton robot. Integrating a robotic device with individualised user electroencephalography (EEG /electrical activity in the motor areas in the brain) and EMG (muscle)feedback would allow more physiological and targeted gait parameters in response to effort, and  confer neuroplastic training effects including neuromodulation of temporal and spatial features of gait.Future integration of EEG/EMGsignals with robotic devices will allow patient initiated movement through thought and/or attempted effort, where currently parameters for devices are therapist set and usage is not functionally driven by the patient. Advancement in this regard is stalled primarily because of difficulty in 3D modelling of gait by EEG. This collaborative consortium through secondments and return and built in knowledge sharing strategies will exchange knowledge and expertise across: Design, development and production of exoskeleton gait devices; neuro-rehabilitation; bioelectric EEG/EMG signal capture and interpretation; mathematical modelling and brain computer interface (BCI) platform development can advance the state of the art in gait rehabilitation after stroke rehabilitation. The proposal  will allow development of 3D modelling of gait, for gait restoration  and explore integration  with robotics from multi-stakeholder perspectives.Aims:1. Define current state of the art in EEG modelling of gait post stroke by systematic review and meta-synthesis2. Complete 3D modelling of gait as visualised gait, overground gait and robotic walking in healthy individuals and stroke survivors3. Develop and test a virtual reality BCI gait training device, including
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Improving the quality of life in large urban distressed areas', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

Most European cities have large urban areas suffering environmental, economical and social distress that results in a high level of political pressure to make rapid improvements Most European cities have large urban areas suffering environmental, economical and social distress that results in a high level of political pressure to make rapid improvements to the quality of life. The LUDA project addresses major strategic planning and development issues with special consideration of the take-off phase as the most crucial and difficult phase of rehabilitation processes. It aims to help decision makers facing the complex problems in large urban distressed areas by facilitating exchange of experience between cities in an European context through a learning process and networking, by analysing problems, by developing methods and measures of improvement, by formulating respective policy recommendations for initiating rehabilitation as well as supporting the implementation of key projects. In addition, from a scientific perspective LUDA serves to enhance the knowledge about the phenomenon of large urban distressed areas.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'CUTTING-EDGE HUMAN IN VITRO AND IN SILICO BIOMEDICAL TOOLS ON BRAIN DISORDERS', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Brain disorders (BD)s have become one of the leading causes of disability in the world with about a third and a half of all Europeans suffering from BD in their lifetime. Patients falling under BDs do not have cure or disease-modifying options and as a result, BDs are one of the major societal challenges with a high economic burden impact for Europe and the rest of the world. The primary aim in VISI-ON-BRAIN is to provide the appropriate training for the participating DCs, guaranteeing that each individual DC is able to achieve and finalize a PhD degree based on their performed research work and at the same time equip them with tools on how to collaborate and work towards new and innovative technologies for modeling BDs. VISI-ON-BRAIN consists of six closely interlinked Work Packages (WPs), closely managed through WP6. The central theme – in vitro and in silico modeling - will be executed through scientific WP1-WP3 – bioengineering, In vitro modelling of BDs and In silico modelling - by which the individual DCs are jointly trained within and across multiple scientific disciplines using different didactic methods in WP4 – education and training - to enable efficient work on his/her own project as well as in joint efforts with other DCs within and across the WPs1-3. Each DC project is directly or indirectly linked to other DC projects and contributes with different pieces of the gear in different scientific WPs, which in turn makes up a major piece of the large machinery to be merged into different scientific deliverables. The education and training and industrial secondments will provide basic DC training in the individual scientific disciplines and inter- and trans-disciplinary training in and across multiple scientific fields, and provide DCs with transferrable, inter-
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Characterisation of the functional heterogeneity of lymphoid organ dendritic cells by proteomic analysis of plasma membrane and endosomal proteins' in the context of a Sixth Framework call.

assistant: **Objectives**

Dendritic cells (DC) are unique in their capacity to induce and regulate immune responses. Their special abilities in pathogen detection, antigen processing and presentation, and communication to T cells are determined by plasma membrane and endosomal proteins. Our knowledge of DC biology is mainly based on studies of in vitro generated-DC, which are not representative of those found in vivo. Clear evidence from the laboratories of Heath, Shortman and Villadangos show that different subtypes of DC show radical differences in antigen handling, T cell activation, and roles in immunity and tolerance.The goal of this project is to compare in depth the protein composition of different DC subtypes as they occur in vivo. We propose to use a proteomic approach to analyse plasma membrane and endosomal proteins from two major DC subtypes: CD4 DC and CD8 DC, in a resting or activated state. The most interesting molecules discovered by the proteomic analysis will be further analysed in functional studies. This project will reveal differentially expressed membrane and endosomal proteins, which could be used to target distinct DC subsets as a strategy to improve vaccination or suppress autoimmunity.The proteomic description of DC diversity we will obtain will be beneficial for the wider scientific community. The feasibility of the project is founded on the expertise and resources available to the scientists involved both at the Immunology Division, Walter and Eliza Hall Institute (Melbourne, Australia) and INSERM U653, Institut Curie (Paris, France), all of which have a demonstrated track record in their respective areas. This proposal will create the opportunity for cooperation between French and third country research institutions and allow transfer of research competencies while r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Affordable flexible system for off-line automated fettling and finishing'.

assistant: **Concept**

There is a major problem in the castings industry in the fettling and finishing area. Large numbers of people are employed in an environment, which imposes a high health risk. Dust, vibration and noise are prevalent. Fettling and finishing also imposes a high cost burden in large and small companies alike, it can represent 40% of the cost of casting production. Current manual practices are inconsistent leading to customer dissatisfaction. This RTD project involving partners from 7 Member States will almost totally eliminate these problems. It will develop and prove an affordable system for controlled fettling and finishing of castings up to 2.5 tonnes, made in batch quantities. This is the area in which most SME's are active and in which no suitable equipment is currently available. The objective is to reduce fettling and finishing costs by 50% and to double the throughput of castings while offering a better quality product.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'SPIRAL2 PREPARATORY PHASE'.

assistant: **Objectives**

The SPIRAL 2 Preparatory Phase project aims to achieve the development and signing of the consortium agreement allowing for the construction of the facility. The SPIRAL 2 project located at the GANIL facility (Caen, France) will deliver energetic rare (radioactive) isotope beams with intensities not yet available with presently running machines. The studies of the properties of nuclei forming these beams or their interaction with stable nuclei is a rapidly developing field of contemporary nuclear physics, astrophysics and interdisciplinary research. Although the Region Basse-Normandie and the French funding agencies (CNRS and CEA) are financing the investment to the extend of 80% of the cost of baseline project, SPIRAL 2 seeks new partners in order to balance the construction budget both of the baseline project and of the new instrumentation necessary for experiments. The Preparatory Phase will deal with the critical financial, legal and organisational issues related to the international character of the SPIRAL 2 facility during its construction and operation phases. Searching for new funding partners will be achieved by direct contacts and negotiations between international partners, their funding agencies and the European Commission as established through the official visits, meetings and workshops. Several critical technical issues have still to be addressed in order to construct the SPIRAL2 facility and associated instrumentation. The corresponding tasks were chosen in order solve remaining technical challenges as well as to attract efficiently European partners. In particular, the accent was put on the new instrumentation for SPIRAL 2. This topic, being the most attractive for scientists, is an excellent tool to convince the funding agencies of international partne
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Alpha1-adrenergic function and dysfunction in heart : Inotropism, hypertrophy and arrhythmias' in the context of a Fourth Framework call.

assistant: **Objectives**

To determine the role of alpha1-adrenergic stimulation in the mechanism of cardiac cellular hypertrophy.To analyse the origin of the alpha1-adrenoceptor induced arrhythmias under pathological conditions (hypertrophy - cardiac insufficiency).To assay variations in (alpha1-receptors and alpha1-triggered second messengers (Ca - InsP3 - pH) under pathological conditions.To investigate the origin of positive inotropisme and its alteration during hypertrophy after alpha1-adrenerglc stimulation.To get new insights in the molecular and cellular mechanisms of alpha1- adrenergic induced hypertrophy and pathophysiological consequences the proposed studies include various technical approaches such as electrophysiology, analysis of mechanical activities, biochemistry and cellular biology on human isolated cells as well as on isolated cells, cultured or not, tissue samples and whole hearts from both genetic and experimental models in rat; complementary techniques that are currently used in one or the other laboratories which will share their expertise.Analysis of the role of Ca ions and particularly the activation of the MAPK cascade will contribute to understand one of the intracellular signalling pathways that is triggered by alpha1-adrenoceptor-mediated cardiomyocyte hypertrophy. Besides this long term effects, acute effects of (alpha1-adrenergic stimulation will be investigated. These include biochemical characterisations such as types and hydrolysis pattern of phosphatidylinositol, receptor density, plasmatic level of noradrenaline. Analysis of the alteration in ionic movements will be performed using electrophysiology and fluxes approaches, particularly on the potassium currents, the major substrates of the antiarrhythmic agents.Mechanical activity will be measured in control a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Transfer of knowledge on lubrication fundamentals in mechanical products' in the context of a Sixth Framework call.

assistant: **Objectives**

Tribology is the multi-disciplinary scientific field concerned with friction, wear and lubrication. Lubrication technology is essential for the facilitation of many technologies, including the primary technologies, such as production of food, textiles and other manufactured goods, communication and transportation. One of the main industrial applications of lubrication technology concerns rolling bearing systems.Though the use of a rolling bearing system has many advantages, several problems do exist such as leakage; failure of lubricant systems and inefficient use of rolling bearing systems. These problems result in significant damages for the environment, extensive energy loss and huge costs. The above mentioned problems and issues present in industrial applications can only be solved with the aid of fundamental scientific knowledge.Therefore the aim of this project is to create a strategic and durable intersectorial partnership in the field of tribology between SKF RDC (a leading global supplier of products, customer solutions, and services in the business of rolling bearings and seals) and two European universities: Luleå Technical University, Sweden and the Institut National des Sciences Appliquées de Lyon in France. The three participating organisations will transfer already available knowledge and set up research activities in order to jointly gain new fundamental knowledge on lubrication of rolling bearing systems.Various transfer of knowledge activities are envisioned, such as numerous visits to make a profound inventory of current research and training programmes, resulting in for example joint research projects, training sessions, and meetings. The research topic of proposed project is highly relevant for Europe as it is expected to lead to improved rolling be