RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Furthering Strategic Urban Research' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

European cities face many significant challenges, including the current economic crisis, urban sprawl, and the longer-term implications of climate change and resource scarcity.  To face up to and overcome these challenges, it has become urgent for all concerned stakeholders to collaborate.URBAN-NEXUS, a coordination action, will develop and use structured dialogues to encourage communication, exchange knowledge and experiences, and build partnerships to promote joint research.  The dialogues will involve a wide range of public, private, and civil society organisations from across the EU27; that are involved with urban research.URBAN-NEXUS has 3 main objectives:•Firstly, it aims to identify innovative ways for urban policy makers and researchers to collaborate to solve the complex and interrelated problems that confront sustainable urban development.•Secondly, it will increase awareness among relevant stakeholders in 5 thematic areas, and allow them to exchange knowledge, collaborate and cooperate.•Thirdly, it will make possible partnerships between relevant stakeholders, in particular researchers and those who apply knowledge, for long-term strategic cooperation across scales and disciplines.The 5 themes that frame the URBAN-NEXUS project are:•adapting to climate change;•increasing health and quality of life;•using land sustainably;•integrating urban management;•integrating information and monitoring.The URBAN-NEXUS consortium, which is led by the Nicis Institute, brings together leading knowledge institutes, research organisations, government agencies and large European-wide networks representing urban interests. Most of the partners participated in URBAN-NET, the European Research Area (ERA) network on urban sustainability formed in 2006.  This ERA-Net aimed to streng
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Heart Failure and Repair' (HEARTREPAIR), addressing dissemination and exploitation.

assistant: **Impact**

HeartRepair uses the lessons of the embryo to answer the crucial developmental questions regarding heart muscle cell differentiation and develop techniques aimed at harnessing stem cells and or recruiting non-damaged myocardial cells from the infarcted heart to facilitate cardiac repair.Myocardial infarction is the leading cause of congestive heart failure mainly caused by excessive smoking and bad dietary habits. However, the cause of the subsequent heart failure is simple, massive cardiomyocyte necrosis which fatally perturbs heart function. However, an effective therapeutic approach is simple: replacement of damaged myocardium with viable cardiomyocytes.Recent advances in the field of stem cell replacement therapies, specifically cardiomyocyte regeneration, gains grace as a realistic alternative for congestive heart repair. Major publications revolve around transplantation trials carried out using either embryonic stem cells or bone marrow derived stem cells. However, Field serious questions the current scientific approach to this research and more importantly if, using current techniques and knowledge, such a goal can realistically ever be reached. Realization of this aim will only be achieved by understanding the underlying principles of cardiac muscle cell formation; the mission statement of HeartRepair.HeartRepair addresses four R&D themes:1. Genes for heart repair and plasticity, integrating clinical knowledge based genome sequencing to identify genes involved in heart development;2. Diversification of cardiac progenitor cells, examining the genetics of cardiac muscle cell formation by exploring the process of cardiomyogenesis and subsequent differentiation;3. Cell interaction and cardiac reprogramming, exploring the details and signals necessary to facilitate a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Retinal Mesh Optoelectronics' (MESHOPTO), addressing dissemination and exploitation.

assistant: **Impact**

Visual sense is vital for all of us. Blindness has severe negative psychological, social, and economical consequences, and degeneration of photoreceptors is a leading cause of it. Photovoltaic retina implants are the current electronic solution to restore vision loss due to photoreceptor degeneration. Since the state-of-the-art implants are based on photodiodes, which face challenges in terms of miniaturization, efficiency, and compatibility with mechanical and structural properties of the retina, artificial vision still falls short to overcome the legal blindness level. We propose a novel concept of Retinal Mesh Optoelectronics that will simultaneously satisfy (a) high-pixel density for high visual acuity, (b) conformability to match the natural curvature of the retina for optimal vision quality, (c) flexibility for coverage of a large area of the retina for a wide field of view, (d) seamless integration to keep the remaining healthy photoreceptors intact, (e) biocompatibility, (f) usage of safe capacitive current, (g) injectability and (h) removability.  Toward this aim, we will initially develop efficient, thin, and cellular-sized photovoltaic neural interfaces based on quantum dots and nanowires. For that, non-toxic quantum dots that have strong light absorption at near-infrared will be synergized with the nanowires that have unique light-trapping and high surface area for efficient photostimulation of neurons. Then, we will translate these devices to porous and flexible tissue-like retinal implants for artificial vision. Starting from the nanomaterial synthesis to optoelectronic device fabrication and bioelectronic mesh formation, this challenging innovation combining nanomaterials, photonics and abiotic-biotic interfaces will be explored from primary neurons up to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Validation Manager - A disruptive turnkey solution for diagnostic test validations', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The need for fast and accurate diagnostics in laboratories is an exceedingly important global issue. It is a mandatory requirement by regulators that the performance of any new clinical diagnostics test must be thoroughly demonstrated, i.e. validated before it can be sold by the diagnostics companies, or taken in use by laboratories. Organizations may easily waste on average 100 000€ a year for validations, which could be saved.Finbiosoft (FBS) has introduced a unique and disruptive cloud-based (SaaS) software, Validation Manager™, which makes validation of diagnostic tests according to requirements truly easy and is able to cut down even 95% of the time needed for validations. The software enables i) diagnostic companies to save dramatically time and money to reach markets faster, allowing them to sell more, and ii) laboratories to be able to cost effectively evaluate and take into use the best available diagnostics. The estimated market potential globally is 750 M€. Finbiosoft's ambition is to revolutionize industry practices and make its solution a de facto tool for managing validations globally in all diagnostics segments. FBS is the only player on the market offering a full turnkey solution, and holds a unique opportunity to grab the global leadership position in diagnostics validations.In the project, FBS will assess the market potential and arising challenges when expanding from the first targeted segment, molecular diagnostics, to other segments like clinical chemistry. Upon completion of the project, FBS deeply understands requirements to commercialize its product to new segments regarding both technical and economic aspects with a plan to achieve the desired de facto status. The outcome is comprehensive business plan and knowledge of the full potential for the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Nonlinear Pricing in Vertically Related Industries' in the context of a Seventh Framework call.

assistant: **Objectives**

Instances of nonlinear pricing in vertical industries typically involves discount schemes where higher volume purchases or those that involve a larger selection of the supplier’s products lead to lower prices. Some of these discount schemes can generate incentive effects that are often associated with exclusive dealing. In absence of efficiency rationale these are often seen as potential mechanisms to exclude competitors and therefore carry a negative connotation in competition law. Disentangling the underlying motivations for loyalty discount schemes is essential for the capability of competition policy enforcement to separate anticompetitive instances from benign ones. This project aims to generate output that serves this end. Its benefits are likely to diffuse into competition law and policymaking.  The applicant has received her PhD at Universitat Autonoma de Barcelona, and holds an assistant professorship at the University of Alicante. She conducts research on industrial economics, and is a dynamic researcher with numerous achievements. To accomplish the project the applicant would spend two academic years in the Economics Department at University College London, a research department in economics. UCL has vast scientific expertise and facilities required for conducting top quality academic research. In addition, its active involvement in interdisciplinary collaborations is valuable for this project.  The proposal would contribute to applicant’s academic career. It would help improve her analytical skills and research training, diversify her knowledge, deepen her project management skills, create opportunities for long-lasting collaborations and get in touch with timely antitrust issues. Through the accomplishment of this project, the applicant aims to build a soun
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'The Ecology and Evolution of Mimicry in a Changing World'.

assistant: **Concept**

Climate change has the potential to decouple interacting species. The EcoEvoMimic proposal will consider, for the first time, the effects of climate change on a mimicry system: hoverflies (Diptera: Syrphidae) that mimic stinging bees and wasps (Hymenoptera). Both groups are economically-important pollinators, and both are currently in decline across much of their ranges. The applicant will establish the ecological responses to climate change in these taxa, and the evolutionary consequences of those responses. The project will provide novel experimental tests for hypotheses that explain the evolution of mimicry across a range of taxa. The project comprises a set of complementary comparative analyses and experimental approaches with innovative combinations of existing paradigms which together give a comprehensive overview of this charismatic and important model system.  The Marie Curie International Incoming Fellowship will provide support for Dr Christopher Hassall (the Fellow), a leading insect ecologist and evolutionary biologist, to join the research group of Professor Bill Kunin (the PI) for a period of two years at the University of Leeds.  As outlined in the application Dr Hassall possesses the unique combination of skills and collaborations that will enable the transfer of valuable skills and knowledge to undergraduates, postgraduates, researchers and teachers at the host institution and across the ERA alongside the successful completion of the EcoEvoMimic project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Migrant Descendants’ Intercultural Competence and their Recognition in the English and Italian Labour Market' to be submitted under Horizon 2020.

assistant: **Abstract**

Migrant descendants (MD) represent an increasingly important share of the European workforce. Their multiple cultural belonging offers potential to develop intercultural competence (IC), a vital asset in contemporary labour markets. Surprisingly, neither migration studies nor literature on IC has ever examined this potential. Filling this gap is crucial if it is to make the most of the opportunities inherent to multi-ethnic societies whilst improving MD’s opportunities in the labour market.Through qualitative research, comparing UK and Italy, MIDIC explores: A) MD’s perceptions of their IC and its development; B) MD’s and employers’ perspectives on MD’s IC use in work organisations. In this way, it sheds light on MD’s IC features and on factors hindering or favouring their development and generates recommendations on how to best utilise this potential in work organisations. Dissemination activities will raise awareness of the contribution that MD could make to society. This interdisciplinary study combines contributions from literature on migration and on IC. It promises advancements in knowledge of MD’s integration and IC conceptualisation and lays the theoretical and methodological basis for a new research area on MD’s IC. The researcher possesses a solid background in migration studies that will be enhanced through collaboration with the Institute for Research into Superdiversity (IRiS) at the University of Birmingham (UoB) (host organisation), which specialises in the study of migration-led diversity through an interdisciplinary perspective. IRiS will support the researcher in strengthening her knowledge of qualitative research methods, extending her core skills and professional opportunities. Fondazione Mondinsieme (Mondinsieme) in Reggio Emilia (secondment organis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Supramolecular engineering of multifunctional systems and devices: the molecular approach to 2D materials' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

SUPRA2DMAT is a multidisciplinary project aimed at exploiting materials engineering, by mastering supramolecular approaches, to combine the outstanding physico-chemical properties of graphene and other 2D layered materials (2DLMs) with the chemical and functional programmability of molecular components, with the ultimate goal of modulating and enhancing the properties of 2DLMs and imparting them a responsive nature. The monolayer nature of 2DLMs makes them extremely sensitive to environmental changes at the nanoscale. Controlled processing and interfacing of 2DLMs with functional molecular assemblies will be attained by means of non-covalent and (dynamic) covalent chemistry approaches. The physisorption of redox, magnetic or optical switches to create crystalline superlattices on 2DLMs will enable the fabrication of high-performance electrical devices capable to simultaneously respond to at least two external independent stimuli. Structurally precise hairy 2D and 3D layer-by-layer porous composites for multianalyte chemical sensing will be tailored via chemisorption of supramolecular receptors of the target analyte onto the 2DLMs. Highest sensitivity and selectivity in the sensing of water molecules (humidity) as well as heavy or alkali metal ions through an electrical readout will be guaranteed by the choice of the receptor and 2DLM and their nanostructuration.The knowledge developed in SUPRA2DMAT will lead to the emergence of a conceptually new generation of multifunctional high-performance devices for applications in optoelectronics and chemical sensing, and on the long term also in energy and spintronics. SUPRA2DMAT will also bring a useful contribution to the development of future emerging technologies based on 2DLMs for light-weight, low-cost and large-area applic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Liver enzyme induction and inhibition as a biological marker of occupational exposure to volatile anaesthetics and other volatile organic chemicals' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

- To determine the ability of volatile anaesthetics (VAs) and other volatile organic chemicals (VOCs) to induce/inhibit cytochrome P-4502E1 and 1A in exposed workers. - To clarify the role of and the relationship between individual genetic make-up (genotype) and occupational or environmental factors in determining toxicity. - To identify individuals with increased sensitivity to VAs/VOCs, by P-450 genotyping and phenotyping and to assess the toxicological significance of enzyme induction/inhibition in workers exposed to these compounds.The participants' expertise in occupational medicine, industrial hygiene, molecular and biochemical toxicology, pharmacology, toxicokinetics, pharmacogenetics and molecular biology will be used in an integrated, multidisciplinary approach to investigate cytochrome P-450 enzymes induction and inhibition as an occupational risk factor. The interaction between occupational, environmental and genetic factors will be studied at different levels of biological complexity: in vitro models, experimental animals and humans. Identification of the specific P-450 isoforms responsible for activation/detoxication of VAs/VOCs (including halothane, isofluorane, hydrochlorofluorocarbons, perchloroethylene and dimethylformamide) will be carried out using purified enzymes in reconstituted systems, transfected human cells synthesising specific P-450s (Crespi cell line) and liver microsomal preparations from rats pre-treated with selective P-450 inducers (betanaphtoflavone, pyridine and phenobarbital). The effects of VAs/VOCs on the P-450 system will be studied at the molecular level. The modification of the prosthetic haem group will be investigated by spectrofluorimetric, spectrophotometric and chromatographic techniques and the formation of adducts to the a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Prostate Diagnosis using Optical Coherence Tomography' (PROCT) targeting Horizon Europe.

assistant: **Abstract**

With 1.3 million new cases worldwide, prostate cancer (PC) is the second most common cancer in men, causing more than 350,000 deaths each year. It is so common that about 1 man in 8 will be diagnosed with prostate cancer during his lifetime. As for any degenerative disease, early diagnosis is crucial to improve patients’ quality of life and reduce the mortality rate. However, the gold standard technique (biopsy) is affected by large diagnostic errors, representing a major limitation to achieve adequate management of PC.The PROCT project aims to validate in pre-clinical stage a semiautonomous robotic approach to PC diagnosis based on Optical Coherence Tomography (OCT), which aims to exactly pinpoint the target lesion and analyse it through an AI and robotic-based imaging setup. This can comprehensively visualize the lesions at the microscopic level in vivo, without taking any physical sample of the prostate. The resulting virtual microscope slide will allow urologists to explore and analyse various suspicious areas in the same procedure without the need to rely on the physical examination of the biopsy samples.PROCT is a paradigm shift in PC biopsy, that is poised to turn a subjective and operator-dependent procedure into a safer and more accurate diagnostic tool. This solution is obtained by merging the AI-based target identification with robotic pointing developed in the previous PoC project PROST with a micro-optical coherence tomography sensor capable to acquire images of the prostate through a needle at cellular-level resolution.The PROCT prototype will be laboratory validated and benchmarked to assess its usability and real time capabilities. It will be also tested and validated on ex-vivo animal tissues and in the cadaver laboratory.