RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'High-throughput oligonucleotide synthesis and NGS for Digital TEXT Storage And retrieval in DNA encapsulated nanofibers', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Incorporating biomolecules as integral parts of computational systems represents a frontier challenge in bio and nanotechnology. Using DNA to store digital data is an attractive alternative to conventional information technologies due to its high information density and long lifetime. However, developing an adequate DNA storage medium remains a significant challenge in permitting the safe archival and retrieval of oligonucleotides.TextaDNA introduces polymer fibres as a novel approach to encapsulating and retrieving information-carrying oligonucleotides. We will develop a complete DNA storage workflow, encoding digital information into DNA base sequences and optimising oligonucleotide synthesis and encapsulation in polymer nano and microfibres. The project is led by nanoGUNE, a nanotechnology research centre, and partners with Eurofins, a leading European company specialising in state-of-art oligo synthesis and next-generation sequencing. We will design next-generation sequencing assays to automate the DNA digital storage readout retrieved from fibres. The enhanced oligo synthesis and sequencing strategies that, TextaDNA will develop are of fundamental interest in the path toward broader use of DNA digital storage, increasing synthesis speed and length of oligos and reducing costs. The consortium will create the conditions for encapsulating oligonucleotides inside polymer fibres and methods to retrieve them. We will establish efficient methods of synthesising oligonucleotides going beyond state-of-art phosphorodiamidate chemistry while ensuring their stability. Further, TextaDNA will also explore ways of incorporating sequencing technologies into reading digital data stored in oligonucleotide pools and expand the data storage capabilities of DNA.TextaDNA will add to the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Open innovation living labs for Positive Energy Neighbourhoods'.

assistant: **Objectives**

The aim of the oPEN Lab is to identify replicable, commercially viable solution packages enabling the achievement of positive energy neighbourhoods within existing urban contexts that are seamlessly integrated into the local energy system as an active micro-energy hub, and to test these technologies and package as an integrated solution at neighbourhood scale.Three open innovation living labs in the cities of Genk (BE), Pamplona (ES) and Tartu (EE) will test combinations of different close-to-market ready technologies and services and study their performance as a unique operating system. Focus is on demonstrating innovations in an integrated approach combining sustainable design tailored to the local context, seamless industrial renovation workflows, renewable energy generation combined with energy storage systems, urban service facilities and smart operation, life cycle thinking and circularity, and this across the whole value chain, targeting the whole life cycle of the building and its neighbourhood, in view of scaling up and wide replication. A user driven and participatory approach with the neighbourhood?s community will be rolled out for a holistic and positive energy vision for the neighbourhood, going beyond citizen awareness raising activities. oPEN Lab is a unique collaboration aligned with the Open Innovation quadruple helix model where a) industry (SMEs, large companies,  start-ups and scale-ups in both construction and energy value chains), b) government (local public administration), c) academia/RTOs and d) civil participants (end users, NGOs) work together to co-create and drive structural changes that will result in high TRL levels, with great focus on exploitation of results and wide replication.


**Keywords:** Building renovation, positive energy buil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Organization, plasticity and perceptual functions of neuronal circuits in a higher olfactory forebrain area' (ZEBRAFISHFOREBRAIN).

assistant: **Innovation**

The brain processes sensory information in a succession of interconnected brain areas. Response complexity tends to increase with distance from the sensory organ, and neurons in higher brain areas exhibit complex response properties that may also reflect memory processes and behavioural associations. Little is known about how such complex representations emerge. I propose to confront this problem by studying forebrain olfactory processing in zebrafish, utilising the extensive studies available on initial processing in its olfactory bulb and its small, tractable brain size. I will focus on the zebrafish forebrain area Dp, homologous to the mammalian olfactory cortex. First, I aim to uncover principles of afferent and internal connectivity and their relation to sensory representation. Neurons impinging upon a single Dp neuron will be identified using a monosynaptically restricted transsynaptic labelling method, and will be related to the neuron’s sensory responses by 2-photon Ca2+ imaging. Optogenetics will complement this part by directly measuring how Dp neurons integrate their pre-synaptic inputs. Second, I will use behavioural manipulations to study how experience modifies sensory representation in the forebrain. To this end, I will use a simple conditioning paradigm to associate odours with either positive or negative behavioural consequences. Sensory representation in Dp will be performed after learning, to identify the effect of behavioural value on connectivity and representation. These results will provide insights into the structure, function and plasticity of neuronal circuits underlying computations in the forebrain.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Open Responsible research and Innovation to further Outstanding kNowledge.' (ORION) under Horizon 2020.

assistant: **Objectives**

The ORION project focuses on triggering evidence-based institutional, cultural and behavioural changes in Research Funding and Performing Organizations (RFPOs), targeting researchers, management staff and high-level leadership. Our long term vision is to “embed” Open Science and Responsible Research and Innovation (RRI) principles in RPFOs’ policies, practices and processes to organise and do research. Since science is about creativity and collaboration, we will extend further collaboration in research by engaging in co-creation experiments with multiple stakeholders. We will try out different “open-experiments” in three key challenge areas: 1) Opening up the research engine – making RFPOs more permeable to receiving input from numerous, distinct stakeholders; 2) Identifying risks and opportunities presented by disruptive technologies; 3) Running multi-stakeholder projects based on citizen science. After an initial assessment and benchmarking exercise, we will use our three challenges as case studies to explore different co-creation methods with multiple stakeholders, and spark dialogue between unusual combinations of actors (e.g. funders and the public, or researchers, industry and the public). We will apply the RRI principles on the scientific process and governance, identify drivers and barriers, interests and values, and eventually produce “prototypes” for current and future societal challenges. Toward raising knowledge on RRI in practice and enriching the current training, we will generate innovative training programmes and modules based on the peer-to-peer learning approach, targeting young researchers and professionals at funding agencies. The consortium, which involves RPFOs from different countries, representatives of RRI stakeholders and experts in social scie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Photonic Skins For Optical Sensing' under Seventh Framework.

assistant: **Concept**

PHOSFOS (Photonic Skins For Optical Sensing) develops and builds on a new paradigm for optical sensors integrated in an unprecedented manner with opto-electronic and electronic circuitry in flexible and stretchable skins for applications in diverse fields including structural health monitoring, automotive industry, aeronautics and aerospace, robotics, healthcare etc. PHOSFOS intends to develop a technology that provides an answer to essential issues that have so far prevented fibre sensors from penetrating the market, which include packaging, fully-fledged system integration, optical coupling and interfacing, dependable strain transfer and reliability. The project positions itself at the pre-competitive intersection of optical fibre sensing and integrated optics. It aims at developing a flexible and stretchable foil in which all necessary optical sensing elements can be integrated; that if relevant to the application can include optical and electrical powering as well as onboard signal processing and wireless communications; that can be wrapped around irregularly shaped objects; that will allow quasi-distributed sensing. To do so the sensing elements in PHOSFOS will rely on special highly birefringent micro-structured optical fibres (MSF) and polymer optical fibres (POF) with fibre Bragg gratings. The silica fibres will be designed to exhibit almost zero temperature sensitivity whereas POF fibres will be used for their very specific property that their length can be stretched up to 300 % before breaking. The optimal Bragg grating writing technology in these fibres, both silica and POF, will be developed. PHOSFOS will focus on embedding these into the sensing skin and on the optical coupling/interfacing to the peripheral opto-electronics and electronics. PHOSFOS will end
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Comparative Modelling of RNA structures at atomic resolution' (CM-RNA) under Sixth Framework.

assistant: **Objectives**

Computational RNA structure prediction is currently limited to secondary structure at the exception of few attempts to predict its 3D conformation. Thus, the problem of predicting the structure of RNA is still unsolved and is part of a major challenge in structural biology: to derive the rules of RNA molecular evolution.This proposal focus on characterizing the underlying principles for comparative modeling of RNA structures at atomic resolution, implementing those principles in a method for comparative modeling, and illustrating its utility. RNA is more like a protein than a DNA because the size, complexity and specific detail of its structure determine its function.Protein comparative modeling is possible because structure is evolutionary more conserved than sequence and because the relationship between sequence and structure can be quantified. At the same time, the number of available protein structures is increasing and sufficient for the derivation of statistical rules for comparative modeling. These requirements are currently meet for comparative modeling of RNA structures.Thus, the challenge for structural computational biologists is to derive the basis for developing an automated, accurate and readily available method for comparative modeling of RN A structures at atomic resolution. The result of this proposal should be such a method, which will be implemented in the MODELLER program currently used at more than 6,000 research institutions worldwide.The application of the method to a large-scale prediction will increase the number of available structures of RNA molecules. Thus, advancing our fundamental knowledge of the relationship between sequence, structure and function of RNA molecules.This is likely to impact various fields of biomedicine, including but not
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Thematic Network on Intelligent Public Transport Systems' (1998-2002) under Fifth Framework.

assistant: **Objectives**

The Tr@nsITS consortium will establish a thematic network (TN) within the urban and regional public transport sector, with the main objective to develop a workplan for future research in Intelligent Public Transportation Systems (IPTS). The TN will establish four sub-groups of experts - mainly from the I(P)TS field, but also from the non-transport related IT-sector, so as to ensure the integration of IPTS within the global Information Society - covering the following areas: 1. Information for travellers; 2. Ticketing and fare collection; 3. Operations and Maintenance; 4. Security for travellers and for personnel. Based on a consolidation of the state-of-the-art and the identification of future societal issues & technological developments, the project will seek to identify new axes for future research and develop a workplan for priority RTD actions within the EU?s 6th Framework Programme and beyond. Dissemination actions and the participation in the TN of a broad range of actors will increase stakeholders? willingness to support, adopt and participate in the future research actions identified.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'From co-transcriptional splicing kinetics to the evolutionary impact of exon and intron definition' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The need to preserve correct splicing is a major source of constraint on sequence evolution. This includes selection on the splice sites as well as on regulatory elements in exons and introns. Are all exons and introns constrained similarly by splicing related pressures? This is a crucial problem not only for understanding genome evolution but also for predicting where disease-causing mutations occur.Any variation in the prevalence of splicing information most likely reflects mechanistic variation in how the splicing process unfolds at different introns. Notably, it is often assumed that the relative importance of intronic and exonic splicing information depends on whether the splicing machinery recognizes introns or exons as the initial unit. However, this common model has never been tested directly because it is currently not possible to investigate splicing mechanism at this level of detail genome-wide. Existing studies on the distribution of splicing information are therefore based on proxies of unclear mechanistic significance, such as intron size. My host lab has developed a nascent RNA sequencing technique that allows unprecedented insight into splicing dynamics transcriptome-wide. They have recently applied this method to Drosophila melanogaster, a species thought to use a diversity of splicing strategies. I propose to use this data, combined with a machine learning approach, to conduct the first genome-wide study into exon and intron definition based on direct kinetic evidence. I will then use population genetics methods to determine how the prevalence and strength of selection on different types of splicing information covaries with splicing dynamics.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Photocatalysis as Powerful Tool For Polyene Cyclizations in Supramolecular Cages'.

assistant: **Innovation**

Biosynthetic polyene cycllization, where complex structures are obtained, represents an impressive example of Nature's a chemist. Organic chemists are trying to emulate the Nature to develop synthetic methodologies base on these cascades. It has been demonstrated that Photoinduced Electron Transfer (PET) can achieve this polyene cyclizations under milder conditions, as plants do during photosynthesis. In this context, fluorinated alcohols are very special solvents in organic chemistry due to their particular chemical and physical properties (e. g. strong H-bonding donor ability, low nucleophylicity). The combination of fluorinated alcohols with PET processes make this strategy unique for develop new biomimetic polyzene cyclization. To achieve PhotoCage 4 main research objectives should be implemented: (a) Design of the supramolecular cage photocatalyst and study of the interaction between them; (b) Application of the designed supramolecular cage - photocatalyst to polyene cyclizations; (c) Study of the reaction mechanims; (d) Impementation and development of an asymmetric version. The proposal also offers me a unique opportunity to develop transferable skills thanks to the courses proposed by Saarland University and Professor T. Gulder wich will be a valuable asset for continuing my academic career.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Designing Trees for the future', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

TREES4FUTURE will make a significant contribution to helping the European forestry sector respond, in a sustainable manner, to increasing demands for wood products and services (among which preservation of forest biodiversity) in a context of changing climatic conditions. To do so TREES4FUTURE will integrate for the first time major, yet rarely interacting forestry communities (and their resources) from geneticists to environmentalists and from communities working at the tree/population scale to those working at forestry landscape/wood basin levels as well as industry concerns.These scientific communities will combine their complementary infrastructures, tools and knowledge and thus fill in the current gaps 1) physical environment vs genetics, 2) basic wood properties vs end-products quality and 3) individuals to forests scales of study. This collaboration will result in a holistic approach integrating abiotic and biotic environmental aspects through biological responses (eco-physiological and pest/disease risk studies), biomass production (breeding and silviculture) and industrial technology (wood quality and technology).The long-term objective of TREES4FUTURE is to provide not only the partners but the whole European forestry community, with an easy and comprehensive access to complementary but currently scattered sources of information and expertise to optimise the short and long-term exploitation of the forest resources by both the research community and the socio-economic players.Providing access to the wider research community to a wide variety of forestry research infrastructures (from state-of-the-art analytical tools to predictive models) via the project will enable TREES4FUTURE to improve, coordinate and validate its offer to the European and International res
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Materials, Components and Footwear with enhanced comfort properties based on nanotechnologies' (NANOFOOT), addressing dissemination and exploitation.

assistant: **Impact**

NANOFOOT main goal is to develop advanced and innovative nanotechnology based solutions for leathers and polymers components for footwear products, aiming a new sustainable and customer-driven production of consumer goods; where the health, environment, high quality of components, fair marketing communication and competitive sales price are combined to promote the competitiveness of the companies.NANOFOOT SMEs have the ambition of exploring the potentialities and the benefits of nanoparticles (NPs) available in the market on the development of new functional materials & products. The final objective is to get differentiated, high added value and marketable materials and footwear consumer goods; that satisfy the needs and expectations of the final consumers.The consortium is constituted by 9 members (5 SMEs and 4 RTD institutions). A balanced and interdisciplinary team is formed by combining the know-how of SMEs with the expertise of the University and Technology Research Centres. The consortium will provide an effective way to develop and transfer knowledge to the companies, a requisite needed to promote innovation and the results commercial exploitation.NANOFOOT RTD and technical activities include:Screening of commercially available cost-effective nanoparticles;• Investigation of the functionalization of processing products, coatings and leathers using nanoparticles.• Investigation and development of polymeric nanocomposites and footwear components.• Develop advanced antimicrobial thermal auto-regulated footwear.• Develop an integrated environmental approach to safeguard consumers, workers, workplace and environmental.• Perform prototype demonstrators and dissemination actions.• Prepare results exploitation by the SMEs and IPR protection.