RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Market Power and Secular Macroeconomic Trends' (2014-2020).

assistant: **Innovation**

In the last four decades, there have been a number of significant secular trends in the advanced economies around the world. Wage inequality has risen sharply, and most of the wage gains have been appropriated by the top 1%. In addition, labor market dynamism and new startups have declined, the labor share of total output has fallen, low skilled wages have stagnated, and there has been reallocation of production from small to superstar firms. During the same four decades, there has also been a sharp secular increase in market power. Firms set higher prices, profit rates are higher, and scale economies are up.In this proposal, I address the question whether these secular trends are related. Specifically, I ask whether the rise of market power has caused these profound macroeconomic changes. The objective is to uncover economic mechanisms that help understand this fundamental transformation and the implications for efficiency and welfare.I propose to investigate both the causes of the rise in market power and its macroeconomic consequences. I distinguish between causes that stem inherently from the market structure (such as antitrust enforcement and Mergers & Acquisitions) and those that result from technological change (economies of scale, intangible assets, and network externalities). Methodologically, this research proposal aims to contribute to the literature on three fronts: 1. the measurement of markups, 2. to derive theoretical results linking market power and macroeconomic consequences, 3. to estimate and quantitatively evaluate these models. The close link between the macroeconomic consequences and the causes of market power renders this a research proposal at the intersection of macro/labor, industrial organization and law & economics. The objective is to inform
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'High Current All Printed Transistors'.

assistant: **Innovation**

The fast evolution of printed electronics, with the photovoltaic technology in primis, is requiring the presence of a valid transistor alternative to the traditional one. The realization of a high current roll-to-roll transistor will interconnect all the different technologies so far developed with this low cost and high throughput method. Our aim is to develop a roll-to-roll transistor capable to of modulate modulating the current to levels that where has not been achieved so far. The fabrication of the transistor will be done considering the lowest environmental impact possible, and containing energy consumption with a temperature below 150 °C. This high current (~mA) transistor will be able to support and assist other technologies and will also be the base for logics and sensing application.The optical studies on the organic material will result in a more controllable production process that for the first time will relate polymer crystallinity directly with an optical characterization technique. The realization of such kind of measurements is not trivial, but will give information on polymer nanoscale structures never investigated before. To do so this technique uses femtosecond pulse in subdiffraction-limited area. This will disclose an unprecedented tool to control the polymer morphology as soon as it is deposited, with enormous consequences in performance control and optimization.The realization of samples and the study of real cases will produce important information regarding this new technology and its real life applications.  In addition, life-time and stability studies can be performed. Then the objective of minimizing the environmental impact of the technology life time cycle will be more realistic. These kinds of studies are also important to explain scienc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Ex vivo cell labelling for in vivo imaging applied to cell therapeutics' (Cenya).

assistant: **Innovation**

While we do not possess magic, modern day medicine can sometimes approach the unbelievable - curing cancer or repopulating diseased heart tissue; all possible due to the advent of cell therapy. However, cell therapy has fallen far short of expectations. Its success requires the ability to monitor and optimise treatments in real time for each individual; necessitating a direct means of monitoring transferred cells. Noninvasive imaging techniques are essential to the success of modern therapeutics. Here, I will build on my work on developing multiscale GMP-ready imaging nanoparticle (NP) agents with the objective of out-licensing the technology to a new commercial venture, Cenya Imaging, to take this work from the bench to the bedside, and I have recruited an experienced CEO to drive this forward. Advisors have outlined a cheaper, faster and simpler path to regulatory approval for Cenya NPs: labelling cells ex vivo and tracking labelled cells after infusion into patients; since, with this approach, Cenya NPs are used to only track cells and not diagnose a disease, the regulatory hurdles are far lower. Recent developments in cell therapeutics have made tracking of cells a very attractive market; specifically (1) increasing investment in CAR-T cells, checkpoint inhibitors (which affect lymphocyte trafficking), and stem cell therapies (40% per annum growth in phase I trials); (2) regulatory push for increased safety and biodistribution data in trials; and (3) a lack of suitable clinical imaging agents. Market size is estimated at €300M; the FDA recently hired 50 new staff exclusively to deal with cell and gene therapies. We will exploit this new market, while also seeing this as the opportunity to play a significant role in the optimisation of cell therapies. We have surveye
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Traditional tomato varieties and cultural practices: a case for agricultural diversification with impact on food security and health of European population' (TRADITOM) targeting Horizon 2020.

assistant: **Abstract**

Tomato is the second most consumed vegetable in the EU and a major dietary source of many nutrients, vitamins and antioxidants. Consumers complaints about the loss of flavour in modern tomatoes, provide an opportunity for the valorisation of traditional tomato varieties, in order to protect them from genetic erosion and the replacement by higher-yielding, pest resistant modern cultivars. Genetic, epigenetic and phenotypic variability and knowledge from farms and in public repositories, will be concentrated in a TRADITOM database and seed repository (O1). The available genetic and phenotypic variability present in TRADITOM varieties, and the genetic and epigenetic differences from modern cultivars will be assessed (O2). For varieties whose cultivation is not sustainable due to unacceptably low yield and/or pathogen resistance, novel F1 hybrids will be generated, retaining the quality characteristics of traditional varieties and incorporating yield and disease resistance traits (O3) Finally, traditional varieties and the impact of traditional cultivation methods will be valorised through a thorough characterization of their composition in term of flavour- and health-related compounds, the identification of consumer preferences, the evaluation of socio-economic factors limiting their market diffusion, and the protection of the most significant case studies through PDO or PGI denominations (O4). TRADITOM is a multidisciplinary translational, multi-actor research project bringing together scientists working in academia, local farmers communities, consumer experts and small seed companies that have preserved the local germplasm, in order to bring to fruition and apply to traditional tomato varieties the enormous knowledge generated on tomato genetics, genomics and metabolomic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Room Temperature Ferromagnetism in Graphite and Fullerenes' (FERROCARBON).

assistant: **Concept**

Carbon is a life sustaining element which, thanks to the versatility of its bonding, is present in nature in various allotropic forms. The extraordinary discovery, recently reported, that some of these allotropes (namely graphite and fullerenes), when pro perly treated, can develop high Curie temperature ferromagnetism (similarly to magnetic elements like iron, nickel etc,) opens a door to a multitude of potential technological applications and, at the same time, upsets the scientific wisdom that strong m agnetism is a property of elements with d and f electrons. Several reliable confirmations of this effect have followed the original discovery. In all cases, however, only a small fraction of the material displays magnetism. A conclusive breakthrough towa rd a light biocompatible bulk carbon magnet will represent a technological revolution with anticipated rebounds in various fields like medicine, biology, electronics, material science etc. This task requires a combined experimental and theoretical expert ise with strong interdisciplinary character to focus in a high risk interdisciplinary research which falls outside the main thematic areas of FP6. The project brings together an experienced team of investigators who are world leaders in this field . The ir skill cover the extensive battery of theoretical, experimental and engineering competencies needed to achieve the ambitious task of producing bulk magnetic carbon.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Open distributed reliable environment architecture and middleware for supervision'.

assistant: **Objectives**

The goal of the OpenDREAMS project is to satisfy the needs of advanced Supervision and Control Systems (SCSs), by providing middleware technology and tools to integrate existing systems and new applications with strong distribution and data management requirements. Typical examples of SCSs are command and control systems for the management of large equipment infrastructures such as telecommunications networks, electricity and water distribution networks, large buildings; command and control systems in the field of transport (air, railway and road) including traffic management and fleet management systems; civil security supervision and control systems for police, fire brigades, health care and territorial administrations at every level of operation (national, regional and local centres). The development and operation of SCSs demand full support to data processing and acquisition, continuity of operations, distribution, permanent data storage. Today, the proprietary nature of most SCSs restricts access from third parties and inhibits integration of new technologies. However, it is unrealistic to think that companies will undertake full scale SCSs replacements; they will operate incremental upgrades of existing systems. This means that systems should integrate new functions while maintaining interoperability with previous versions and external systems. Currently, the market does not provide any answer to these issues, that is a development and operation platform satisfying the above requirements.In this project, we will design an open interoperable object-oriented platform able to integrate industry standards, commercial products and new developments. In order to achieve the overall goal of the project, we have identified a number of major objectives: to integrate existin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'INTElligent inteGration of RAILway systems', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

The InteGRail project aims to create a holistic, coherent information system to integrate the major railway sub-systems and deliver a higher level of coordination and cooperation between the key railway processes. The objective is to achieve higher levels of performance of the railway system in terms of capacity, average speed and punctuality, safety and the optimised use of resources. By creating innovative concepts in the areas of train control and monitoring, maintenance, management and communications, the proposed project will completely re-define the basic elements required by each system. The project will assess the needs of rolling stock, infrastructure, traffic management (ERTMS), train operation and propose intelligent procedures to process all available additional information to its best advantage. An all-pervasive, wide-band communication infrastructure, offering a suitable digital data link between trains and the ground installations, will be defined and proposed as the future reference standard in railways. Requirements coming from the definition of new services, both for train staff and passengers, will also be incorporated. The project will seek wherever possible to build on results achieved by previous projects in the fourth and fifth FP (ROSIN, TrainCom, EuRoMain) and will cooperate with concurrent projects in FP6 (e.g. ModTrain, EUR2EX).The specifications developed in the project will be proposed as candidate standards, through dissemination to and cooperation with relevant standardisation bodies. The results to be achieved are fully intended to fulfil key objectives stated in existing and upcoming EC directives and TSIs.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Stratospheric climatology using UV-visible spectroscopy-3' (1994-1998) under Fourth Framework.

assistant: **Objectives**

The objectives are those of the Network for Detection of Stratospheric Change (NDSC); Investigation of the long term change of stratospheric constituents and establishment of a data base to be used for correction of possible drifts of satellite instruments. The strategy is to continue existing long term measurements from a network of European ground-based UV-visible spectrometers at high and lower latitudes by means of collection and analysis of data and to provide an independent calibration of satellite sensors of the atmosphere. The research especially aims at a climatology of O3, NO2 columns and, where possible, OClO and BrO. The data base for the UV-visible region reaches back to 1987/88. Therefore trends and interannual variations will be discernible. The goals are to perform continuous observations to make the earliest possible identification of changes in the ozone layer and to discern the cause of the changes. The objectives include NDSC validation of instruments, vertical profiling of O3 and NO2, validation of retrieval algorithms and intercomparison of BrO and OClO column measurements with the purpose of including these in the NDSC data base. This data base will be used to test and improve multidimensional stratospheric chemical and dynamical models, thereby enhancing confidence in the predictive and assessment capabilities of these models.Stratospheric measurements will be carried out throughout the project period by ground-based UV-visible  instruments. The unpredictable movements of the Arctic vortex required instruments at various locations. The  vortex position will be followed, to determine the location of stations relative to the vortex. Measurements will  be made at high and at lower latitudes. An important objective is to monitor the effect of air mas
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Peptide and DNA-based strategies for vaccination against major human infections' to be submitted under Fourth Framework.

assistant: **Abstract**

Immunization with bacterial plasmids containing the genes encoding antigens (DNA vaccines) have been shown to generate effective humoral and cellular immune responses. For the design of effective DNA vaccines there are two important considerations; the choice of antigen(s) and the mode of administration to obtain the desired immune response. The DNA vaccine construct can contain more than one gene, each coding for an entire protein. In contrast to immunization with fragments or short peptides derived from recombinant proteins, DNA vaccines allow expression of proteins in their native conformation thus inducing better antibody responses. Furthermore, the problems of MHC restriction at the T cell level are avoided since it is likely that T cell epitopes for the majority of MHC molecules will be generated. However there are several disadvantages to using genes coding for full length proteins. First, bacterial or protozoal DNA with different codon usage may not be easily expressed in mammalian cells. This may be more pronounced with longer molecules. Secondly, there can be certain parts of the molecule that may contain harmful epitopes or immunodominant epitopes may reside in polymorphic regions. Thirdly, mammalian glycosylation may alter the conformation of the expressed molecule such that antibody recognition is affected. We propose to address some of these problems of DNA vaccination by constructing synthetic genes encoding regions of protective antigens lacking T cell epitopes that are harmful or polymorphic. These will be produced in a polyepitope string together with B cell regions and mimotopes of conformational B cell epitopes. The peptides containing the T cell epitopes will be selected to contain the peptide motifs able to bind a wide range of MHC Class I and Clas
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'European Gender Medicine Network' (EUGENMED) targeting Seventh Framework.

assistant: **Abstract**

Research addressing sex and gender (S&G) in biomedical sciences and health care research is emerging as a novel and highly promising field. Interaction of S&G related mechanisms leads to different manifestation of frequent diseases such as infarction, heart failure, diabetes, rheumatic disease, etc. in women and men. Research in this area will lead to novel, better targeted and therefore more efficient treatment strategies than the previous global approaches and will increase prevention and healthy life expectancy .We suggest to produce an innovative roadmap for implementation of S&G in biomedicine and health research. To achieve these objectives we will develop EUGENMED into an open European Gender Health Network that includes all stakeholders and decision makers.We will organize 6 meetings with all stakeholders that will result in recommendations, guidelines and teaching materials for the implementation of S&G research for target audiences, doctors, medical associations, teachers, students, researchers, industry, health policy makers, funding agencies and politicians. Materials shall be disseminated through a European Gender Health Portal. The aim is to create a truly multi- sectorial sourcing of knowledge, a key factor for building consensus and helping close the participatory governance gaps. Inclusiveness, openness and transparency will be key principles. Dissemination of S&G strategies to the next generation of medical interventions and therapies shall improve the health of European citizens. Project outcomes will be fed into relevant policy processes at the EU level e.g. Horizon 20/20. EUGENMED will lead to significant innovations by introducing S&G into medical practice and research and improve European citizens’ health and Europe’s standing in biomedicine.Keywo