RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'PaperWorks : Interweaving Paper and Digital Documents' (PAPERWORKS) under Sixth Framework.

assistant: **Objectives**

Paperwork is concerned with providing distinctive ways of interleaving paper documents with digital materials. We will provide people with new forms of functionality in everyday environments through seemingly mundane artefacts. The project will involve a range of activities which at each point give critical consideration to the production, practice and use of everyday documents. The project will focus on developing a core technology for interlinking established content in paper and electronic domains. This will be demonstrated through a robust application where a non-obtrusive pattern on the paper allows users to interrelate content with associated digital information. Paperwork involves innovative developments in the production of novel substrates, inks, reading devices and the integration of software and communication resources as well as requiring an adaptable information architecture. Paperwork draws on innovative research to develop support for authoring information and associated links. The development of the hardware, software and information infrastructure will be informed by empirical studies of people using paper documents and associated tools as part of their everyday activities coupled with studies of those who have the responsibility for producing digital and paper content. The project will examine how publishers, professionals and other 'users' currently design materials using particular media. Drawing from the findings of these studies we will undertake technical interventions where we provide people with various augmented technologies as well as authoring tools to support the production of content and interlinking of materials. Hence the project develops hardware solutions, a software and information infrastructure, and design augmented paper products. D
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Transcription in 4D: the dynamic interplay between chromatin architecture and gene expression in developing pseudo-embryos' (DynaTrans).

assistant: **Innovation**

During mammalian embryogenesis, key events involving DNA and regulatory molecules over seconds and nanometers affect and are affected by, a major reorganization of the genetic material in the nucleus over hours and micrometers. How these scales are spanned and integrated into the course of development remains a major unresolved challenge. Progress in this quest is difficult, either because current model systems suffer from severe technical limitations or because existing analytical approaches probe individual spatial or temporal scales thus ignoring their evolving interactions. Traditional live imaging lacks the spatial resolution to accurately delineate chromosome organization at the scale of genes, while bulk molecular assays are ill-suited for studying development over time. Here, we propose a multi-disciplinary approach to the dynamics of developmental gene regulation to understand the details of the underlying mechanisms and their deployment over time. We combine and apply optical, molecular-genomic, and theoretical tools to recently available mammalian pseudo-embryos, allowing unprecedented precision in developmental staging, a large amount of material, and easy optical access. By focusing on select gene loci we track transcriptional activation and the interactions of distal DNA elements in real-time along with the associated chromatin dynamics using interaction profiles. Our datasets are iteratively distilled into mathematical models of increasing scope, converging towards an integrative dynamic polymer model that simultaneously captures long-timescale chromatin rearrangements as well as short-timescale motions of genetic regulatory elements and transcriptional activity. We then challenge these models via genome editing and temporally defined interventions by bui
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Effect of processing technology on the quality of aquaculture feeds'.

assistant: **Concept**

The main objective of the project is to verify the reliability of several innovative chemical methods (aspartic acid racemisation, proportion of SH to S-S bonds and Near Infrared Reflectance (NIR) techniques) to predict the protein digestibility of protein fed to farmed fish. The prediction of the true nutritive value of the protein ingredients used in aquafeed preparation has a central role in allowing a correct use of food resources, reducing wastes and thereby contributing to establish a real sustainable aquaculture, both from an economic and ecological point of view. The kinetics of aspartic acid racemisation and S-S bonds formation will be studied to elucidate the role of different processing parameters (pH and moisture content of the raw material, oxygen pressure, temperature and duration of the thermal treatment) on the protein quality of fish meal, soya meal and extruded diets, aiming at defining indicative guidelines for the production of feeds ingredients and fish feeds characterized by higher protein quality. The availability of reliable and rapid predictive chemical methods to evaluate the quality of the protein ingredients of fish feeds would in fact allow the European fish feed manufacturing industry to produce a dietary protein of high quality which is expected to be well utilized by fish, to allow reduction in the protein content of the feed and to reduce the environmental impact of fish farming.Suitable analytical methods are now available for the determination of the chemical parameters under study. A preliminary calibration of NIR equipment in order to get predictive estimates of fishmeal digestibility has been achieved. Laboratory equipment for the controlled heat treatment of raw material for fishmeal manufacture has been constructed and is now work
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Ultra-fast Antimicrobial Susceptibility Test for diagnosing antimicrobial resistance to provide personalized antibiotic treatments' (Nanosynex) under Horizon 2020.

assistant: **Objectives**

Antimicrobial Resistance (AMR), is the ability of microorganisms to resist to antibiotics treatment, contributes to 700,000 deaths a year (25,000 deaths in Europe). Besides, The financial implications of AMR proliferation are devastating for the global healthcare system. The current implementation of antimicrobial stewardship programs in hospitals has not been enough to mitigate the overuse and misuse of antibiotics. Current AST (Antimicrobial Susceptibility Testing) diagnostic methods are highly accurate but take too long (a few days) forcing doctors in many case to prescribe non-personalised treatments. The overuse and misuse of antibiotics, due to the lack of efficient solutions to detect bacterial resistance at an early stage, allows the emergence of “superbugs” and the spread of the resistant bacteria in the environment resulting in more infected patients and increasing the major global threat of Antimicrobial Resistance (AMR). Nanosynex product provides a revolutionary, low-cost, ultra-fast AST (Antimicrobial Susceptibility Testing) technology that delivers results in an average of only 4 hours in average, and as little as 2 hours for certain bacteria type. Nanosynex will allow physicians to get same-day AST results and to prescribe personalised and effective antibiotic treatment, with a unique test that will save at least one day of hospitalization per patient, as well as avoid pandemics outbreaks such as the current case of COVID-19. Consequently, Nanosynex will contribute to reduce the spread of resistant bacteria and significantly reduce the large economic burden associated with antimicrobial resistance. This EIC project aims the industrialization and scalability of Nanosynex benchtop and cards, performing the clinical trials to get the CE mark for its commerc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Novel ingredients for healthier foods' under Sixth Framework.

assistant: **Concept**

New ingredients with specific functional and biological properties are required to manufacture new product. The Millard reaction constitutes an efficient procedure to improve the functional properties of proteins without using chemical reagents that could be toxic and difficult to remove. Enzymatic hydrolysis of proteins has also been proposed as an effective treatment to produce ingredients for functional foods. However, the number of investigations related to the effect of the Millard reaction on the biological properties of proteins is still limited and the possible use of this procedure combined with enzymatic hydrolysis to obtain bioactive peptides is practically unexplored and this is the aim of this investigation. New ingredients will be obtained by Millard reactions of soy proteins and carbohydrates with different molecular weight and reactivity combined with enzymatic hydrolysis by employing 3 different enzymes.Both gyration and enzymatic hydrolysis procedures will be carried out under controlled conditions. Peptides will be isolated using chromatographic techniques. Peptides obtained from gyrated and non-gyrated proteins may be different due to the presence of carbohydrates, which may affect enzymes digestion. Peptides may possess specific and probably better and different characteristics than those obtained from the intact protein.Allergenic effects will be evaluated and employed as the main criterion of selection. Other biological properties, including antioxidant, antithrombotic and antihypertensive activities will be also evaluated. Bioactive peptides will be selected and their functional properties (solubility and thermal stability) will be assayed. Peptides showing desirable biological and functional properties will be proposed as new ingredients for for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'SenseGuard – A breakthrough respiratory monitoring device incorporating novel nanotechnology-based sensors' under Horizon 2020.

assistant: **Concept**

Respiratory rate is a vital sign used to monitor the progression of illness both in hospitals and at home, particularly when dealing with at-risk patients. The continuous monitoring is key for patients with respiratory conditions (i.e. asthma), Chronic Obstructive Pulmonary Diseases (COPD) or pneumonia, with cardiovascular conditions, as well as elderly with comorbidities and prematurely born babies or babies with respiratory conditions.SenseGuard  respiratory monitoring device - is a decision support tool that assists practitioners in better monitoring patients with respiratory conditions like and at risks of deterioration. SenseGuard enables effective generation of alerts to clinical personnel, at the earliest moment following a change in patient’s status, at the hospital or at home. Due to its direct and high-resolution respiratory sensors, SenseGuard is able to continuously monitor pulmonary function on a breath-to-breath basis, unmatched by other technologies. SenseGuardTM can effectively monitor all at-risk patients.NanoVation is an Israeli SME, founded in 2014, which develops and integrates nanomaterial-based sensors for medical applications and general purposes. Run by an experienced and multi-disciplinary team, NanoVation was granted several EU and non-EU projects, one of which awarded the 2018 Innovation Award by the European Commission. So far, NanoVation has raised and invested more than € 2.5M into the development of SenseGuard. To have it fully projected at a European and global level, NanoVation needs a further investment of €2.2M to complete product development and set up a solid EU value chain.The proposed work in Phase 1 of the SME instrument fits into the company overall plan to reach the market by contributing the financial resources needed to plan a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Investigating the biodegradation and fate of plastics in the gut of xylophagous insect larvae' under Horizon Europe.

assistant: **Concept**

The recalcitrance of plastics leads to their accumulation in the environment, where physical deterioration in absence of degradation is causing widespread pollution. Microplastics have been found to enter the food chain and to bio accumulate with hitherto unknown long-term health effects, making plastic pollution one of the major environmental problems of our time. In recent years, a plethora of plastic degrading microorganisms and enzymes have been reported, however their degradation efficiencies, especially for conventional plastics, are often underwhelming. Enzymes capable of plastic degradation share a close homology to enzymes involved in the degradation of natural plant derived polymers, such as esterases, cutinases, lipases. It is therefore no surprise that most plastic degrading microorganisms and enzymes are found in the soil environment and compost, where plant litter is a dominant carbon source. Recently, microorganisms inhabiting the guts of xylophagous insect larvae were reported to degrade highly recalcitrant plastics such as polyethylene, polystyrene and polyurethane. However, evidence of this degradation remains scarce and to date few enzymes capable of degrading these polymers could be confirmed. in this regard, xylophagous insect larvae harbour much untapped potential for the discovery of unknown plastic degrading microorganisms and enzymes that could help mitigate plastic pollution. This project will benefit from my previous experience with stable isotope probing, sequencing analysis and plastic degradation by using carbon-13 labelled plastics to investigate plastic fate and degradation in the gut of xylophagous insect larvae. Cryosectioning of the larval gut and state-of-the-art imaging technologies will be used to study plastic fate. Stable isotope
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Biological effects of environmental pollution in marine coastal ecosystems (BEEP)' in the context of a Fifth Framework call.

assistant: **Objectives**

Biological markers allow the direct determination of pollutant impact of living organisms in aquatic systems. While new emerging biomarkers are actually under evaluation, some common markers are in a validation-phase and may be used as assessment tools for the quality of the marine environment. The goal of this research programme is to evaluate the potential of using biological marker determined in marine organisms (fish, bivalves) as a means of assessment of chemical contamination and to investigate the socio-economic implications for certain selected zones for coastal communities dependent from marine resources. Different types of coastal European environments (Baltic Sea, Mediterranean Sea, North Atlantic Sea) will be investigated by the participants who will co-operate on the three selected environments through a long term study
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Virtualized Storage Services Foundation for the Future Internet' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The goal of the VISION project is to advance the competitiveness of the EU economy by introducing a powerful ICT infrastructure for reliable and effective delivery of data-intensive storage services, facilitating the convergence of ICT, media and telecommunications. This infrastructure will support the setup and deployment of data and storage services on demand, at competitive costs, across disparate administrative domains, providing QoS and security guarantees. In doing so, VISION will lay a foundation for the Future Internet, radically extending earlier generations of service infrastructures.<br/>The prime deliverable of VISION will be an architecture and a reference implementation of a cloud-based infrastructure building on open standards and new technologies, capable of optimised delivery of converged data-intensive services. We will demonstrate how this infrastructure, where virtualisation plays a key role, supports emerging Telco/Media services that are not supported today. We aim to achieve significant and quantifiable improvements in service delivery productivity, quality, availability, reliability and cost. Scientifically, our work will advance the state-of-art in several dimensions, including:NEW MODEL OF DATA STORAGE, using objects with metadata to support effective access and management, enabling unprecedented scalability and simplification of storage services.DATA MOBILITY AND FEDERATION, enabling comprehensive data migration and interoperability across remote locations, overcoming current limitations.COMPUTATIONAL STORAGE, introducing a technology for specifying and executing computations close to storage, reducing overheads.CONTENT-CENTRIC STORAGE, facilitating access to data by content and its relationships, relieving applications and users from the need
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Closely Related Languages: Processing, Attrition and Exposure', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Mainland Scandinavian (MSc) marks a fascinating linguistic scenario: relying on mutual intelligibility, speakers use their native language (L1) when conversing with foreign MSc-interlocutors and keep doing so even if immersed in the target speech community for years. This raises the question if non-native speakers of a closely related target language (Ln) use different grammars or resort to the L1 grammar when processing the Ln, whether parsing it causes attrition, and if any of this is modulated by exposure. CloReLa (Closely Related Languages: Processing, Attrition and Exposure) addresses these issues by comparing processing and judgment data of native speakers of Norwegian and non-native speakers with L1 Swedish or Danish. To this end, we employ an innovative combination of on- and off-line methods: Eye-Tracking while Reading (ETR) and Acceptability Judgment Tasks (AJT), conducting in-person studies at UiT and collecting data from speakers in Sweden and Denmark via web-based surveys. Considering closely related languages serves to close important knowledge gaps: these exhibit a broader range of contrasts than dialects, no common standard to fall back on and a slowly deteriorating mutual intelligibility. Whether non-native speakers postulate dedicated rules and are more prone to attrition or not has extensive implications for models of the cognitive organisation of linguistic systems and factors affecting their formation. CloReLa emphasizes the potential of closely related varieties and sparks methodological advances by promoting a novel mix of methods to study (un)grammaticality in parsing. The action allows the PI to build on psycholinguistic and theoretical expertise and trains him in ETR and transferable skills, an ideal mix of training-through-research and formal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Pamir : 5 th international conference on fundamental and applied mhd' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Proposal abstract. The measure is focussed on the participation of countries from former USSR (Candidate countries CC and Central and Eastern European Countries other than Candidate Countries CEEC) to the 2002 pair conference on MHD. The main objectives of the proposal are: to develop the cooperation between western and eastern countries, to allows the dissemination of researches from eastern countries, to help in the development of a new program based on a project of a big experimental infrastructure in Riga (Ampere program) to offer a frame for a mid term review of the program 6 of COST: Magneto dynamics of Liquid