RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Next-Generation Cardiac Tissue Engineering: Smart Self-Regulating Patches' to be submitted under Horizon 2020.

assistant: **Abstract**

Ischemic heart disease is a major cause of death in the Western world. There is no sustainable regenerative therapy available at the moment, with cardiac transplantation being the only therapy. However, tissue engineering is envisioned as a true regenerative therapeutic alternative. Despite the incremental improvements no technology is currently available that can provide on-line monitoring and reporting of the engineered tissue performance, and if needed, automatically activate regenerative processes. As one initial step in that direction, we have recently shown on a non-implantable chip-supported level that a sensory system can be integrated with engineered tissues, providing report on cardiac electrical activity. In this proposal, I plan to expand far beyond the state-of-the-art and develop a conceptually new approach to engineer the next generation of smart implantable cardiac patches. These patches will integrate complex electronics with engineered cardiac tissues to enable on-line monitoring and at the same time self-regulation of the tissue function. Since cardiac performance will be recorded over time, physicians could follow heart regeneration in real-time, providing new means for the disease management. To achieve this goal I will first develop new porous, stretchable and biocompatible microelectronics enabling electrical activity recording and stimulation. The electronics will interact with an efficient electroactive controlled release system enabling on-demand release of biomolecules. The system will be integrated with a 3D biomaterial scaffold and cardiac cells to compose the microelectronic cardiac patch (microECP). Development of feedback loop software will ensure efficient regulation of the patch’s function over time. Next, we will elucidate the interpla
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'PORTABLE COMMUNICATION ASSISTANT FOR PEOPLE WITH ACQUIRED DYSPHASIA' (PCAD), addressing dissemination and exploitation.

assistant: **Impact**

Dysphasia is a language disorder caused by brain damage, often as the result of a stroke, and most frequently occurs in people over 60. Many potential users of communication aids are still active and need more powerful, flexible communication devices than those currently available. The Portable Communication Assistant (PCA) will provide functional communication which can be integrated into speech and language therapy. It is a hand-held computer with inbuilt touch screen, speech recording, playback and communication technologies, based on the Apple ?????. Software complying with emerging industrial standards will ensure an extensible modular product able to integrate with other rehabilitation systems and accommodate future developments. A user-centered approach will empower users and therapists to control the development process themselves.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Smart roots for reducing greenhouse gases emissions from rice cropping' in the context of a Horizon Europe call.

assistant: **Objectives**

Rice production is the main agricultural source of greenhouse gases (i.e., carbon dioxide; CO2, nitrous oxide; N2O and methane; CH4). Scientific evidence suggest that greenhouse gases (GHGs) produced and accumulated in rice paddies (flooded soils) can be vented out to atmosphere through plant tissues. However, information on the plant characteristics influencing such GHGs emission processes is scarce. The mechanisms of GHGs diffusion from rhizosphere to and along the roots and the vent of these GHGs to atmosphere as well as the permeability coefficient of roots to GHGs are largely unknown. This project aims to identify characteristics of rice roots that reduce both the vent of GHGs through plant tissues from soils to atmosphere (through root apoplastic barriers) and the production of GHGs in soils (oxidation of CH4 to CO2). Moreover, this project will study the root permeability to GHGs and the anatomical and chemical characteristics contributing to GHGs diffusion through plants. This project will use a multidisciplinary approach combining state-of-the-art physiological measurements including microsensing technology (for in vivo gas fluxes), gas chromatography, mass spectrometry and microscopy characterization of plant tissues. It is hypothesized that genotypes with tight barriers to radial oxygen loss will have less permeability to GHGs. Moreover, genotypes with no barriers to radial oxygen loss, high number of laterals and an efficient roots system for O2 transport will allow high CH4 oxidation to CO2, thus reducing the venting of this potent GHG to atmosphere. This project will identify root phenotypic differences among rice cultivars and this will serve as a basis for developing high yielding cultivars with desirable traits reducing GHGs emissions from flooded soils
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Staff Mobility to Action Resilient, Restorative, and Regenerative Transitions & Societies' under Horizon Europe.

assistant: **Concept**

The SMAR3TS project arises as a response to climate change and environmental degradation. It orchestrates an ambitious international, interdisciplinary, and intersectoral staff exchange program for research and innovation, aimed at accelerating sociotechnical transitions for inclusive and sustainable growth. It actively tackles grand societal challenges that endanger global stability and prosperity, and adversely impact fundamental human needs such as food, mobility, energy, and housing. Rising temperatures, extreme weather events, sea-level rise, loss of biodiversity, and disruptions to ecosystems all have far-reaching consequences that transcend borders and require collaboration to develop timely and innovative solutions. SMAR3TS builds a Powerhouse Consortium with amplified network effect by uniting cross-disciplinary expertise of researchers and practitioners from 23 beneficiary partners, and 13 Associate/Third Country Partners working on research excellence through secondments, conferences, workshops, summer schools, knowledge-sharing platforms and activities to transform research outputs into tangible outcomes. United in diversity, SMAR3TS network spearheads innovations across various sectors to support resilient, restorative, and regenerative futures. By leveraging Open innovation strategies, SMAR3TS facilitates knowledge exchange, capacity building, and the co-creation of actionable solutions. By enabling a Quadruple-Helix approach (i.e. university-industry-government-civil society collaboration) and offering advanced training opportunities on research translation, futures thinking, foresight and other necessary tools and techniques, it equips researchers with key skills to design pathways for societal impact. Overall, SMAR3TS pursues a proactive strategy to bui
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Commercial service platform for user-relevant coastal water monitoring services based on Earth observation' (CoastObs) under Horizon 2020.

assistant: **Objectives**

Coastal zones are very productive areas, offering many valuable habitats and ecosystems services and attracting human settlements and activities. The intensive concentration of population and excessive exploitation of natural resources puts high pressure on coastal ecosystems leading to biodiversity loss, habitat destruction, pollution as well as conflicts between potential uses and space competition. Several European directives aim at sustainable management of coastal waters, retaining or restoring a high ecological status and safeguarding ecosystem services. Increasing pressure and stricter regulations increase the need for efficient monitoring solutions. Where traditional in situ sampling is insufficient to characterise the highly dynamic coastal environments, Earth Observation (EO) provides a synoptic view and frequent coverage. With the launch of the Copernicus Sentinel satellites, operational water quality services become a business opportunity.CoastObs will develop a service platform for coastal water monitoring with validated products derived from EO. In dialogue with users from various sectors, CoastObs will develop innovative EO-based products: monitoring of seagrass and macro-algae, phytoplankton size classes, primary production, and harmful algae as well as higher level products such as indicators and integration with predictive models. CoastObs will establish sustainable supply chains that can be directly integrated into the users’ systems. The CoastObs consortium has the knowledge and ambition to develop services that are commercially viable, grow in capacity and thus create new jobs. The business case is to define user groups with common requirements, so tailored products can be developed at highly reduced costs per user. Setup of efficient data structure
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Implementation of Virtual Testing in Safety Regulations' (IMVITER), addressing dissemination and exploitation.

assistant: **Impact**

Computer aided engineering is a routinely used technology for the design and testing of road vehicles, including the simulation of their response to an impact and the prediction of the risk of injuries sustained by the potential victims. But, so far, the release of a vehicle on the market still depends on the verification of the product compliance with safety standards through a series of type approval physical tests. To increase car industry competitiveness by reducing the burden of this type approval test system and to improve road safety by raising the quality level of protection measures, recent initiatives have been taken by both industry and public authorities, to promote the use of alternative ways (e.g. virtual test through numerical simulation) to check vehicle compliance with safety standards.   The main objective of this project is the implementation of virtual (VT) procedures in existing safety standards by consolidation of advanced VT technologies, analyzing the ensuing costs and benefits and looking for the improvement of homologation procedures as well as setting the base for improvement of integrative safety.   The achievement of this objective implies among others, that the accuracy of the simulation models and procedures can be assured and rated independently of the modelling process, software tools, computing platform and the performing organization (end user). Procedures that consider uncertainties due to different real tests results (depending on the lab performing), input parameters dispersion, etc. will be taken into account in these processes.   In this project, the future potential of Virtual Testing will be investigated not only to fully substitute real testing (RT) in regulations but also to define procedures for fully virtual testing includin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Unraveling novel Archaeal Metabolic Pathways impacting Greenhouse Gas Emissions' (ARCHAEBOLIC).

assistant: **Innovation**

Archaea are remarkable microorganisms that form next to bacteria and eukaryotes one of the three domains of life and have shaped Earth’s biogeochemistry and climate for billions of years. These microorganisms are the main producers of the greenhouse gas methane. Especially in view of climate change, it is crucial to understand all factors impacting greenhouse gas emissions. Methanogenic archaea are at the center of my research. Recent breakthroughs in this field have been driven by the discovery of many new archaeal lineages via (meta)genomic sequencing. However, physiological characterization and isolation attempts of archaea lag far behind and the evolution of methanogenic archaea is still heavily debated. Now is the right time to investigate the still underexplored metabolic capabilities of (methanogenic) archaea, their impact on greenhouse gas emissions and to enrich novel archaea. I recently discovered a metabolic pathway enabling archaea to produce methane and/or CO2 from wood components and, in silico, from prevalent methylated compounds such as chloromethane. The novel enzyme systems involved are widespread and new metabolic pathways involving a variety of methylated substrates can be predicted, suggesting an important role of archaea in anaerobic conversions of lignin and various methylated compounds to methane and/or CO2. Therefore, I aim to (i) characterize these novel enzyme systems biochemically and in regard to their evolution, (ii) study the physiology of the archaea using these systems and (iii) evaluate the role of these archaea in the environment and for methane and CO2 emissions. This proposal has the potential to revolutionize our view on the metabolic versatility of archaea by unraveling novel mechanisms of methane and CO2 production in a ground-bre
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Strengthening Evidence-Based Policy Practice for Sustainable Food Systems under the EU-AU Partnership' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Food and nutrition security and sustainable agriculture (FNSSA) are among the critical development concerns in Africa. FNSSA is among the policy priorities in many African countries and at the center of the AU/EU international development agenda. FNSSA was the priority R&I area in the AU-EU High Level Policy Dialogue on Science, Technology, and Innovation. This was further substantiated by the establishment of the Pan-African Network for Economic Analysis of Policies (PANAP). StEPPFoS thus, aims contribute to the FNSSA 10-year roadmap and the global transition towards sustainable food systems through the implementation of activities that link PANAP to the FNSSA partnership. Specific objectives are (1) to improved capacities of stakeholders (2) to enhanced science-policy interface (3) to improve strategies that promote scientific support within policy development (4) to expand and strengthen the PANAP Network. StEPPFoS will be implemented through its 8 work-packages (WPs) over a period of 48 months. Capacity building, stakeholder engagements, participatory monitoring, evaluation, and learning are the main methods to be used to deliver StEPPFoS objectives whiles adhering to open science principles and effective data management practices. The consortium is well positioned to deliver these objectives as it draws on the expertise and experiences of its partners drawn from both Europe and Africa credible academic, research, and policy institutions.


**Keywords:** Sustainable Food System, PANAP, Policy Impact Analysis, AU-EU Partnership
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'European Vaccine Research and Development Infrastructure' (TRANSVAC2).

assistant: **Innovation**

TRANSVAC2 is the follow-up project to its successful predecessor project TRANSVAC, the European Network of Vaccine Research and Development funded under FP7. The TRANSVAC2 consortium comprises a comprehensive collection of leading European institutions that propose to further advance with the previous initiative towards the establishment of a fully operational and sustainable European vaccine R&D infrastructure. TRANSVAC2 will support innovation for both prophylactic and therapeutic vaccine development based on a disease-overarching and one-health approach, thereby optimising the knowledge and expertise gained during the development of both human and animal vaccines. This will be achieved by bridging the translational gap in biomedical research, and by supporting cooperation between public vaccine R&D institutions of excellence, related initiatives and networks in Europe, and industrial partners. TRANSVAC2 will complement and integrate with existing European research infrastructures in both the public and private sectors. TRANSVAC2 will function as leverage and innovation catalyst between all stakeholders involved in vaccine R&D in Europe and -by providing integrated and overarching vaccine R&D services- will contribute to the development of effective products to address European and global health challenges, to controlling the burden and spread of infectious diseases, and reinforce the economic assets represented by vaccine developers in Europe.The impact of TRANSVAC2 will be maximised by two external advisory bodies. An independent Scientific & Ethics Advisory Committee will provide recommendations surrounding scientific-technical and ethical issues, whereas the coordination of TRANSVAC2 with other related initiatives and the further promotion of the long-term stabili
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'GENETIC, MOLECULAR AND PHYSIOLOGICAL DETERMINANTS OF WATER-USE EFFICIENCY AND DROUGHT RESISTANCE IN MAJOR FOREST TREES' (DELTA), addressing dissemination and exploitation.

assistant: **Impact**

Background :Drought is a crucial factor for the survival and growth of trees, especially in the Mediterranean area of Europe. In the recent decades forest decline in several forest tree species has been attributed to recurrent drought occurence. Improved adaptation of forest trees is important both for improved growth and because of the danger of climate change (it is likely that plant communities will, in addition to enhanced temperature, have to face more severe drought conditions in the future).The objective is : to provide the ecophysiological and genetic base for improved drought adaptation of some major European forest tree species. Short description of the project :The project deals with the water-use efficiency and drought tolerance in maritime pine, Scots pine, Eucalyptus and Chestnut. A new method using the carbon isotopediscrimination is used to analyse the inter-and intra specific variation, the molecular and physiological bases of water-use efficiency (Delta"), growth and drought tolerance. Quantitative genetic parameters such as juvenile-mature correlations for "Delta" will be calculated using trees from both open pollination and controlled pollination . Genetic markers and early selection criteria for effective selection will be found. The main result will be the establishment of a marker assisted selection for drought tolerance."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'PROMOTING ACTIVE AGEING: FUNCTIONAL NANOSTRUCTURES FOR ALZHEIMER’S DISEASE AT ULTRA-EARLY STAGES.' (PANA).

assistant: **Concept**

Alzheimer’s disease (AD) is the leading cause of dementia and loss of autonomy in the elderly, implying a progressive cognitive decline and limitation of social activities. Progressive aging of EU population will increase the magnitude of this problem in the next decades. Currently, there is not an effective method for the early diagnosis of AD. Therefore, there is an urgent need to develop new effective early diagnostic and therapeutic strategies to help in delaying the appearance of the most adverse symptoms of this disease. To defeat this challenge, PANA project bases its approach on the importance of tau oligomers in the early pathophysiological processes of AD. The effective strategy will be based on two fundamental pillars;  on one hand, efforts will be focused on multimodal PET/MRI imaging which is gaining relevance as the best solution for diagnostic purposes due to the complementary advantages of both technologies, combining the high structural characterization of tissue provided by MRI with the enhanced sensitivity of PET imaging. On the other hand, the challenging development of a theragnostic nanostructures will be focused on tau oligomers detection,   which would have to deliver theragnostic agents into the brain to provide in situ diagnostic and therapeutic effects. Therefore, PANA project focuses on developing theranostic nanostructures that specifically recognize very-early molecular markers of AD, and can be detected by means of non-invasive imaging methodologies (MRI and/or PET, which are already common techniques accessible in most hospitals) and eventually provide a therapeutic action if needed.To achieve this goal, we propose a unique consortium which combines neuroscientists, nanotechnologists, molecular imaging experts, clinicians and Small/Medium