RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Abstraction Layer for Implementation of Extensions in programmable Networks' (ALIEN) targeting Seventh Framework.

assistant: **Abstract**

ALIEN will deliver an innovative network abstraction mechanism targeting the control and management convergence and interoperability of heterogeneous network elements building strong foundations for Software Defined Networks.To achieve this, ALIEN proposes to adopt the concept of Network Operating System (NOS), a distributed system running on top the hybrid, heterogeneous network infrastructure, which creates a global view of the network elements and their capability.The NOS of ALIEN will be based on control and management framework of OFELIA FIRE facility. ALIEN will extend OpenFlow control framework of OFELIA and its architecture to support abstraction of network information of equipment that are alien to the OpenFlow technology such as optical network elements, legacy layer2 switches, network processors and programmable hardware (FPGA).Building on its novel NOS, ALIEN introduces the concept of the control program paradigm, which operates on the global view of the network. and support new network technologies  in layer0, layer1 and layer 2 both in core and access.The NOS of ALIEN utilizes a novel hardware description language as well as a functional abstraction mechanism for uniform representation of any type of network hardware and their capabilities/functionalities that doesn't support OpenFLow (i.e. alien hardware). The language will describe capabilities of hardware, input and output signal format, and topology information to describe the pipelining of actions on specific hardware. The abstraction mechanism will hide hardware complexity as well as technology and vendor specific features from OpenFlow control framework.ALIEN project aims to experimentally verify its solution for describing network device capabilities and controlling its forwarding behaviour of all
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Arrhythmogenic right ventricular cardiomyopathy / dysplasia: clinical registry and data base, evaluation of therapies, pathology registry, dna banking.' (1998-2002) under Fifth Framework.

assistant: **Objectives**

Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is a progressive, genetically determined cardiac disease that is a major cause of unexpected sudden death in the young and athlete in Europe. Because of its rarity, there is a need to collect data on a large scale, to set up a clinical and pathological registry to evaluate different treatments and to create a bank of DNA from affected families. The proposed research is a multidisciplinary multicenter collaborative study to investigate clinico-pathologic and genetic aspects of ARVC/D with these aims:a) prospective longitudinal follow-up study to identify patients at risk of cardiac arrest;b) evaluation of different therapies efficacy;c) ultra structural and molecular pathology study to understand the etiopathogenesis;d) genetic studies with the ultimate goal to identify the specific defective genes and the influence of the genotype on the clinical course.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Genetic Analysis of Temperature Sensation and Nociception in Caenorhabditis elegans' in the context of a Seventh Framework call.

assistant: **Objectives**

Pain is a major medical concern and there is an undeniable need to improve the therapeutic options in pain management. In this project, a simple model organism is used to identify and characterize new potential drug targets.Nociception is defined as the neural processes of encoding and processing noxious stimuli triggering pain. Nociception and temperature sensation are related processes. The general goal of this research project is to shed new light on their molecular and neural basis, by using the small nematode Caenorhabditis elegans. This model organism presents several advantages, including the availability of a complete nervous system wiring diagram, efficient genetic techniques, and a stereotyped avoidance behaviour in response to noxious heat, providing a simple readout of thermal nociception. Recent work by the applicant has demonstrated the suitability of this model. New assays were developed to quantify the heat avoidance behaviour and a pilot mutagenesis screen led to the identification of several genes, which mutation impairs noxious heat avoidance. The specific goals pursued in the present project are:1) to characterize the interplay between the recently discovered “heat avoidance” genes2) to identify more genes required for heat avoidance, by scaling up the genetic screen3) to identify the neurons involved, by using cell-specific gene rescue in mutants and by neuronal ablation4) to understand the logic of the neural circuit involved by expressing light-activated channels enabling an on-demand artificial neural activationBecause thermal nociception mechanisms appear to be at least partially conserved between worms and humans, characterizing the genetic and neural pathways involved will provide novel insights on potential therapeutic target for pain managem
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Understanding signaling in photoreceptors involved in the regulation of bacterial photosynthesis genes using serial crystallography and time-resolved spectroscopy.' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Photosynthetic organisms need to sense environmental light effectively in order to regulate cellular processes. AppA (Activation of Photopigment and PUC A protein) and CryB (cryptochrome B) are two flavin (FAD) containing photoreceptors found in the facultatively photosynthetic bacterium Rhodobacter sphaeroides and depending on the oxygen levels can regulate the expression of photosynthetic genes by light. Photoexcitation of AppA and CryB is accompanied by changes on their conformation and their affinity to partner binding proteins to initiate signaling transduction processes. The mechanisms by which AppA and CryB regulate downstream signaling events is not known. Thus there is substantial interest in capturing the conformational landscape that lead to the signaling state and in understanding how absorption of light by the flavin is coupled to these conformational changes.  The aim of the project is to provide atomic level characterization of the photoactivation mechanism of AppA and structural information on the photocycle of CryB. To achieve our objectives, we will use a combination of biochemical methods, ultrafast transient absorption spectroscopy, QM/MM (hybrid quantum mechanics/molecular mechanisms) calculations and time-resolved structural methods. The latter include TR-serial crystallography (SX) at synchrotrons (SSX) and X-ray free electron lasers (SFX) and TR-solution scattering (small-angle, SAXS and wide-angle X-ray scattering, WAXS). Ultimately, this project will provide a molecular movie of the AppA that features the structural changes occurring upon blue-light illumination and significant information on the photocycle of CryB. The proposed research lies on the implementation of new instrumentation and novel approaches to advance our knowledge on how photo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'EPICA - Strategic partnership for the co-design of an innovative and scalable eportfolio ecosystem to improve the quality and visibility of skills', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Technology is driving change in Africa and knowledge has become a key driver of growth and development. Moreover, education needs to meet the demands of the work place and provide the skills and competencies needed to foster local economies. However, a severe mismatch exists between the skills of young workers and the skills that employers need for the emerging economies. EPICA (Strategic Partnership for the Co-design of an Innovative and scalable ePortfolio ecosystem to improve the quality and visibility of skills) aims to contribute to address this skills-gap through a process of co-design, adaptation, implementation and validation of an innovative and scalable Competency-Based ePortfolio, with an international partnership that includes industries, leading educational organisations, four universities in three Sub-Saharan countries (Open University of Tanzania, Makerere University from Uganda, Maseno University from Kenya,  and the African Virtual University) and one EU University (Open University of Catalonia). EPICA’s outcomes will support:• Universities to deploy and implement the new Competency-Based pedagogical methodologies to face the increasing market demands in term of better-skilled workers• Students (and workers) to make more visible and comparable their skills and competencies acquired in formal and non-formal education• Employers and companies to identify the most reliable and suitable candidatesWith a market-oriented approach, EPICA involves end-users’ communities in the whole process to ensure that the ePortfolio meets users’ and market’s requirements. The pilot in four universities (MAK, OUT, MU, UOC) and the Validation phase will provide the data for evaluating end-users’ behavioural responses, and the means to build a robust and sustainable model, the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Analysis of protein corona formation on nanoparticles by DNA barcodes'.

assistant: **Innovation**

Nanoparticles (from 1 to 1000 nM in diameter) are widely used in point-of-care diagnostics due to their large surface area and versatile biofunctionalization. However, when used in matrices such as blood plasma and other complex biological fluids, nanoparticles are known to attract proteins that form coronas around the nanoparticles. These coronas block binding sites, cause non-specific interactions, and cause aggregation among the nanoparticles, resulting in lower signals, higher background, and large variabilities in the assays. Proteomics studies have analyzed the overall protein corona composition on different nanoparticles, depending on size, surface chemistry etc. Microscopic studies have been used to monitor the kinetics of corona formation on nanoparticles in simplified systems. However, protein-protein interactions and cooperative effects in corona formation, and their interference in diagnostic assays involving affinity reagents, have not been studied yet in a comprehensive way. In this proposal, I will adress those questions using DNA-assisted protein technology, where proteins are labeled with DNA barcode tags. The ligation of proximal barcodes will reveal protein-protein co-localizations within coronas and their interactions with affinity reagents such as antibodies. The analysis will give unique insight in the internal structure of coronas and will shed light on the origin of corona-induced nanoparticle-nanoparticle aggregation processes and nanoparticle-surface interactions, which is very important for nanoparticle-based point-of-care diagnostics.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Trusted GNSS Receiver' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The TGR project represents the development of a highly innovative security platform and target application exploiting current and future GNSS as well as augmentations systems such as EGNOS. In order to leverage the power of GNSS for access control and position attestation applications, it is necessary to develop a GNSS receiver technology able to provide an acceptable level of intractability towards known and future attacks. Development of such technology not only provides a platform for the target mass-market application, an access control token, but also ensures development of European intellectual property that can be leveraged for a myriad of security applications and future research, presenting significant market opportunity
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'European biogas initiative to improve the yield of agricultural biogas plants'.

assistant: **Concept**

The main objectives of the EU-AGRO-BIOGAS Project are to develop and demonstrate a standard methodology to assess the methane yield of several regionally available raw materials as substrates for an agricultural biogas plant, to develop and demonstrate an automatic monitoring, management and early-warning system for agricultural, medium to large scale biogas plants and to optimise and demonstrate innovative approaches to improve biogas yield and energy output at agricultural biogas plants.The consortium combines know-how from universities, applied research institutions and companies. To ensure an efficient technology transfer into demonstration activities at full-scale commercial agricultural biogas plants, selected operators (SMEs) of medium to large scale agricultural biogas plants have already agreed to provide access to their plants, being the main beneficiaries of the project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Reinforcing Additive Manufacturing research cooperation between the Central Metallurgical Research and Development Institute and the European Research Area' (AdM-ERA) targeting Seventh Framework.

assistant: **Abstract**

The overall aim of the AdM-ERA project is to integrate the Central Metallurgical Research and Development Institute (CMRDI) into the European Research Area (ERA), by developing cooperation with European research and innovation organisations in its 2 strongest research topics: A) Additive Manufacturing of Ti and CoCr alloys based prostheses, and B) Additive Manufacturing of biocompatible ceramic materials: HA, PEEK and TCP.These are research topics highly relevant to the FP7 NMP and FP7 PPP-FoF work programmes.Additive Manufacturing (AdM) is a generic name for layer based manufacturing techniques that create physical models directly from computer data without the need for tooling. Using AdM, products can be made from plastics, metals or ceramics by depositing and joining material in a layer by layer process.CMRDI is a major research centre with a high potential for integration into ERA. AdM research work started in 2004 within CMRDI, in Egypt.  This AdM-ERA proposal aims to develop the CMRDI research capacities to explore novel applications such as the additive manufacturing of human-specific prostheses from titanium, cobalt chrome and bio-ceramic materials using high energy laser based selective laser melting systems. CMRDI now seeks to develop its AdM capabilities further by partnering with European research partners who can bring specific areas of expertise in Additive manufacturing technology and techniques.The AdM-ERA project will build upon CMRDI’s existing strengths as a high-quality research institution via capacity building activities with the following 3 excellent European research and innovation organisations: i) Loughborough University, ii) Technical University of Cluj-Napoca, and iii)Intelligentsia Consultants Ltd.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Creating ERA in Central Europe', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

The main objective of the project is to create synergy for virtual networking and strengthening of the European Research Area (ERA) in Central Europe by networking and twinning the best research centres, organisations and associations. Through series of specialized activities the project will help to establish new links and to start cooperation between Centres of Excellence and best research institutions in Candidate Countries and leading research centres, Networks of Competence in Member States as well as established European Networks of Excellence.The project will provide an opportunity to exchange best practices" and to master skills in proposal development aimed at preparation of successful proposals for new NoEs, IPs and STREPs. The workpackage activities include selection of the best research teams from CCs, in particular Centres of Excellence (INCO, NAS-2 Call - long list) and to define their profiles, analyse their strengths, weaknesses and needs. This will allow to carry out a mapping of excellence exercise defining common areas activities and RTD potential of best research centres in CCs. As a next step the "virtual networks of excellence" (VNoE) will be established integrating research activities in selected areas as a preparatory step towards further integration.Apart from that bilateral and multilateral contacts between best research centres and VNoE in CCs and European organizations and associations, Networks of Competence, EIGs, leading research centres and industry in Member States will be established. Contacts will be facilitated by carrying out the Get in touch meetings defining the cooperation and twinning possibilities. Cooperation will be established also with existing NoEs and IPs, IRC institutes, large facilities. Specialized workshops w ill assis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Blue light second harmonic gallium-arsenide quamtum well lasers grown on high index planes by molecular beam epitaxy'.

assistant: **Objectives**

Research objectives and content The objectives of this research are to design and fabricate a vertical cavity surface emitting laser using ultra clean molecular beam epitaxial gallium-arsenide (GaAs) growth technology, and to use this laser structure to obtain blue light emission based on the second-harmonic generation inside the cavity. This will be achieved by exploiting the non-linear optical properties of strained GaAs grown in the (311)B and (411)A directions and by using Bragg reflector technology. A wide range of high resolution optical spectroscopy, electron and scanning probe microscopy will be carried out on laser sub-structures in order to ensure that the molecular beam epitaxy growth is optimised for the device. The mode structure, threshold behaviour and second-harmonic generation of the laser will, as well, be characterised. Training content (objective, benefit and expected impact) Small surface em emitting blue light source on GaAs substrate should be obtained and because of the nature of the geometry of the device, ease of coupling into more sophisticated optical systems will be ensured. The project will then demonstrate a prototype technology for blue emission which can, for example, be further developed into large systems for information storage by optical means. Blue emission from semiconductors is of prime generic importance for data storage, displays, projection systems, military needs..etc... All the experimental techniques used in this research and the interaction with industry will be of obvious benefit and provide training in a field of growing importance for Europe. Links with industry / industrial relevance (22) Links have been established with the GEC company which has a major interest in the manufacture of optically based systems for data st