RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Biogenic emissions in mediterranean area - Phase II:-1996-1997'.

assistant: **Concept**

To complete the collection of emission and concentration data of selected gases from vegetation by supplementary in-field measuring campaigns, scaling-up these data to the entire Mediterranean area.The Biogenic Emissions in the Mediterranean Area (BEMA) project is a European project with the primary aim  of quantifying the emission rates of selected reactive gases from vegetation to the atmosphere in the  Mediterranean Basin. The project is focussed on those trace gas species that take an active part in tropospheric  photochemistry especially reactive volatile organic compounds (VOCs) and reactive oxygenated species. The  data are of value for the parameterisation of tropospheric chemistry models and in particular for the assessment  of the role of these compounds to ozone formation. The BEMA project has been divided into two phases. The  first one, partially accomplished within the frame of the Environment programme for the period 1994-1995  funded by the EC as BEMA - Phase I, has been focussed on a series of intensive field campaigns carried out  at different test sites representative of Mediterranean ecosystems in Italy, France and Spain. Emission fluxes  and ambient concentrations of primary compounds and their reaction products have been determined together  with the seasonal and annual variability of emission rates and concentrations.  The second phase of BEMA will focus on:  -modelling of vegetation emissions as a function of environmental and physiological parameters;  -using a GIS (Geographic Information System)-based micro- and meso-scale model to combine area/time related data with the pertinent emission factors of the Mediterranean Basin;  -evaluating the ozone forming potential of biogenic VOCs with respect to the anthropogenic ones (backed by laboratory ex
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Physical Aspects of the Evolution of Biological Complexity'.

assistant: **Objectives**

One of the most fundamental issues in evolutionary biology is the nature of transitions from single cell organisms to multicellular ones, with accompanying cellular differentiation and specialization. Not surprisingly for microscopic life in fluid environments, many of the relevant physical considerations involve diffusion, mixing, and sensing, for the efficient exchange of nutrients and metabolites with the environment is one of the most basic features of life. This proposal describes a combination of experimental and theoretical research aimed at some of the key mysteries surrounding transport and sensing by and in complex, multicellular organisms, and the implications of those findings for the explanation of driving forces behind transitions to multicellularity. There are two main components of the research. The first involves studies of single and multicellular algae which serves as model systems for allometric scaling laws in evolution. Of particular importance are the synchronization dynamics of the eukaryotic flagella that provide motility, enhance nutrient transport, and allow phototaxis in these organisms. The second thrust involves investigation of the ubiquitous phenomenon of cytoplasmic streaming in aquatic and terrestrial plants. Despite decades of research, there is no clear consensus on the metabolic role of this persistent circulation of the fluid contents of cell. Building on recent theoretical developmnts we will study its implications for internal transport and mixing, homeostasis, and development in large cells. In each case, state-of-the art experimental methods from physics, fluid dynamics, and cell biology will be used in combination with advanced theoretical methods for the study of the stochastic nonlinear PDEs that form the natural description
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Cryogenics, Accelerators and Targets at HIE-ISOLDE' (CATHI), addressing dissemination and exploitation.

assistant: **Impact**

CATHI is a mono-site ITN with CERN as main host institution, offering research training in the application of advanced accelerator technology, beam instrumentation, ultra-high vacuum, cryogenics, radiation protection and advanced material technologies in one of Europe’s leading Radioactive Ion Beam facilities (ISOLDE) at CERN, and its future upgrade (HIE-ISOLDE).The proposed upgrade, which consists of the design and construction of a Super-Conducting linear accelerator and associated high-power target, offers tremendous opportunities for research training in an international, multidisciplinary environment, thereby ensuring that the expertise present in Europe will continue playing an important role in the progress of nuclear physics and related fields.Training projects will have concrete objectives and deliverables. The young researchers will be supervised and mentored by internationally recognized experts and have access to state-of-the-art equipment. Hands-on project training will be supplemented with formal training courses in relevant and related fields, and a wide variety of complementary training courses, colloquia and seminars. Mobility within the ITN will ensure exposure to complementary research and industry environments.CATHI will provide ESRs and ERs with unparalleled research training opportunities in the framework of established, trans-national research networks (ISOLDE Collaboration, EURONS, ENSAR). It will provide hands-on experience through participation in the R&D, construction and commissioning of the super-conducting linac systems and in the design study to prepare for a future increase in intensity of the PSB beam.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'European Strategic Wind Tunnels Improved Research Potential' to be submitted under Seventh Framework.

assistant: **Abstract**

The proposed project ESWIRP aims at enhancing the complementary research potential and service capabilities of three strategic wind tunnels in Europe both in terms of productivity and quality. The concerned wind tunnels are ONERA S1MA Modane, DNW-LLF and ETW. The main ideas leading to the proposal have been (i) the identification at European level by the aeronautical community (ACARE) of the strategic wind tunnels for Europe needed to maintain and enhance the leadership of European aerospace industry and science,(ii) the EREA recommendation that the reduction of emissions, noise and fuel consumption by aviation requires the contribution of these infrastructures and (iii) the recognition that efforts have to be made at community level, in a targeted and coordinated way, to further integrate these strategic wind tunnels at a world class level. The ESWIRP project is fully responsive to the objectives of the Capacities – Research Infrastructures Programme. It will enhance research and innovation capacities throughout Europe and contribute to ensuring their optimal use. The activities planned under this project aim at optimizing the utilization of the three strategic wind tunnels and improving their performance by new long-term investments for the benefit of scientists and customer industries. ESWIRP responds to the so-called ‘targeted approach’ of the Integrating Activities of the FP7 Capacities Work Programme: Infrastructures following the FP6 I3 model: (i) Networking activities, (ii) Trans-national access and/or service activities and (iii) Joint research activities. A Joint Management Board will be established by the three facilities for coordination of all ESWIRP activities and consolidation of integrating objectives.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Innovative tools enabling drinking WATER PROTECTion in rural and urban environments'.

assistant: **Objectives**

High-quality, safe, and sufficient drinking water is essential for life: we use it for drinking, food preparation and cleaning. Agriculture is the biggest source of pesticides and nitrate pollution in European fresh waters. The overarching objective of WATERPROTECT is to contribute to effective uptake and realisation of management practices and mitigation measures to protect drinking water resources. Therefore WATERPROTECT will create an integrative multi-actor participatory framework including innovative instruments that enable actors to monitor, to finance and to effectively implement management practices and measures for the protection of water sources. We propose seven case studies involving multiple actors in implementing good practices (land management, farming, product stewardship, point source pollution prevention) to ensure safe drinking water supply. The seven case studies cover different pedo-climatic conditions, different types of farming systems, different legal frameworks, larger and smaller water collection areas across the EU. In close cooperation with actors in the field in the case studies (farmers associations, local authorities, water producing companies, private water companies, consumer organisations) and other stakeholders (fertilizer and plant protection industry, environment agencies, nature conservation agencies, agricultural administrations) at local and EU level, WATERPROTECT will develop innovative water governance models investigating alternative pathways from focusing on the ‘costs of water treatment’ to ‘rewarding water quality delivering farming systems’. Water governance structures will be built upon cost-efficiency analysis related to mitigation and cost-benefit analysis for society, and will be supported by spatially explicit GIS anal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Behavioural Responses to Intelligent Transport Systems'.

assistant: **Objectives**

Given that nowadays traffic demand exceeds existing road (and public transport) capacity at particular times ITS (Intelligent Transportation Systems) become an increasingly important tool for increasing the road capacity and make optimal use of it. However, the effects of ITS cannot be understood from existing travel demand theory. It can be concluded that the evaluation of ITS measures requires theories and models that describe both ITS and behavioural responses in a dynamic way, as opposed to the traditional models which describe travel behaviour as an equilibrium situation under average travel conditions. In addition, modelling the interaction between ITS and behaviour requires that apart from discrete choice behaviour also learning and adaptation behaviour and activity scheduling need to be included in traffic forecasting models. A better understanding of these behavioural aspects is crucial to apply ITS measures such that the full benefit in terms of avoiding congestion and maintaining accessibility is gained.In particular, if ITS is to be applied in a more strategic manner than today, a better understanding of behavioural responses is essential. Therefore, a Euro-workshop is proposed, with the aim of bringing together well-known researchers from various disciplines and creating a valid theoretical base for further research and development of forecasting tools. In addition, the workshop will be organised such that young researchers are able to learn from experts in the field and receive feedback on their own reserach work. The state of the art in describing and modelling responses to ITS, not only in the EU but also in the US and Japan, will be presented. The workshop will bring together leading scientists in the fields of ITS, travel demand modelling, microscopic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The Dance of Molecules:  Rhythmic Systems through Organic Catalysis' under Horizon Europe.

assistant: **Concept**

Inspired by natural oscillatory systems that govern countless processes, from circadian rhythms to cellular metabolism, and the essential role of catalysis in both bio- and synthetic chemistry, this project aims to systematically design and construct modular, tunable organic chemical oscillators with catalytic functions. These oscillators will not only serve as time-keeping systems but also autonomously control and catalyze additional chemical reactions. The Belousov-Zhabotinsky reaction demonstrated that sustained chemical oscillations are possible, sparking decades of research. However, most existing chemical oscillators are based on redox chemistry and their harsh conditions and lack of versatility make them unsuitable for broader applications. In preliminary studies we developed the first catalytic oscillator based on small organic molecules. Building on this proof-of-concept, we propose to develop methods that allow the construction of biocompatible chemical oscillators tunable to a wide range of potential applications. The project is structured into three closely interconnected Work Packages (WP1-WP3). WP1 focuses on streamlining the design and optimization of oscillators using predictive models and parameter estimation techniques. WP2 will explore a variety of organic catalysts and solvents to create a versatile suite of oscillators with a diverse range of catalytic functions adaptable to various conditions. WP3 will explore a number of promising use cases of biocompatible catalytic oscillators to demonstrate their potential in real-world scenarios, including time-controlled polymerization processes and periodic drug synthesis.Integrating innovative computational modeling with automated experimental workflows will overcome the current limitations in oscillator de
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'A portable instrument (PINE) for the autonomous detection of atmospheric ice nucleating particles aimed at the research, global monitoring and cloud seeding markets' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

It is becoming increasingly clear that a class of atmospheric aerosol particles which catalyse ice formation have a profound impact on clouds, precipitation and climate. For example, recent research demonstrates that massive cloud systems the size of Western Europe are almost completely removed by sufficient ice nucleating particles. However, the global distribution of ice nucleating particles is extremely poorly characterised, in part due to the lack of instrumentation which can be used for the autonomous quantification of these important particles. In my ERC Consolidator grant (MarineIce) we have developed the first instrument to automatically measure atmospheric ice nucleating particles: the Portable expansion chamber for Ice Nucleating particle mEasurements (PINE). PINE allows the repeated formation of an artificial cloud and counting of resulting ice crystals which allows us to derive the ice nucleating particle concentration. The overarching goal of CountIce is to demonstrate that the PINE chamber can indeed be used to quantify the ice nucleating particle concentration in the atmosphere while being autonomous, easy to use, have high sensitivity and low background counts, have a high time resolution, and work over a wide range of temperatures (relevant to the full spectrum of clouds that form in the Earth’s atmosphere). CountIce will therefore create value in PINE, allowing us to take the necessary steps towards commercial products which will be aimed at i) the atmospheric research community; ii) the cloud seeding community and the iii) the global atmospheric monitoring networks.CountIce will give my team the time and resources needed to adapt and develop PINE into an instrument which meets the needs of paying customers, provide the demonstration of its use in an a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'A blood based biomarker identifying early Alzheimer Disease's pathology', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Alzheimer’s Disease (AD) poses an unbearable impact in patients’ life, through progressive loss of cognitive capacities and overall quality of life. In Europe alone, there is currently a €280 bn yearly expenditure related to AD and ~10% of the population above 65 years old is currently affected by the disease, a figure that is expected to triple in the immediate future.No treatment alternatives are available for AD patients with diagnosed disease and the existing diagnostic tools are very time consuming and expensive (6 months / 10.000 EUR). While AD is not curable at final stages of disease, detection at early stages offer several treatment alternatives for example through counseling and/or dietary interventions.Detection and treatment of AD in its initial stages could provide major therapeutic and societal benefits. Treatment strategies at early stages could either slow down or even cure AD which would dramatically reduce the health care costs.PreDiagnostics will exploit and transfer research knowledge developed by its founders to a commercial setting and provide a diagnostic tool to identify patients at early stages before disease is evident. Through the VERDAD project, PreDiagnostics will finalize the final regulatory steps and introduce into the market a novel, accurate and cost-effective blood biomarker detection tool. This tool directly analyses the patients’ brain metabolism and detects reduced clearance of beta-amyloid which is the first step in AD pathology.The VERDAD project will allow for market introduction of a disruptive diagnostic test to identify AD decades before clinical signs are visible. This will facilitate early disease diagnosis and implementation of prevention strategies in likely patients. We have developed necessary collaborations to roll-out
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Molecular mechanisms underlying synaptic maintenance and rejuvenation'.

assistant: **Objectives**

The deterioration of brain function and prevalence of dementias are some of the most striking and unfortunate consequences of ageing. Proper neuronal function relies on accurate signal transmission via synapses. While the basic cell biology of synaptic transmission is well studied, how precise activity is maintained over time remains poorly understood. Several age-dependent neurodegenerative conditions, characterized by the build-up of protein aggregates, affect synaptic function. These observations are consistent with a model where defects in the repair mechanisms that clear away defective proteins may constitute the basis for synaptic dysfunction and neurodegeneration. However, the processes that control protein rejuvenation at the synapse remain elusive. Autophagy is a process that is well suited for this purpose as it has emerged as a major means by which the cell can degrade dysfunctional components but a specific role for autophagy at the synapse has not been established. Levels in autophagy have been strongly linked to longevity and neuronal health. I hypothesize that autophagy plays an important role in synapse maintenance and that synaptic autophagy is disrupted during ageing and in neurodegenerative diseases. I will utilize a diverse set of approaches to elucidate the link between autophagy and changes in synaptic function during ageing in Drosophila. By generating novel optogenetic tools, I propose to test how the precise modulation of autophagy can influence synaptic function and whether boosting synaptic autophagy is beneficial in ageing and disease conditions. Furthermore, I will conduct a large-scale genetic screen for identifying genes regulating synaptic autophagy. Finally, I will explore the intriguing connections between synaptic proteins implicated i