RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Pom1p kinase regulation in control of cell polarity in fission yeast' (1998-2002).

assistant: **Concept**

In the fission yeast Schizosaccharomyces pombe microtubules are essential for specification of cellular domains, such as cell ends and the cell centre. During interphase, microtubules are required for the continuous delivery of polarity factors, to the tips of the cell. At the cell centre, microtubules are necessary for medial positioning of the nucleus, which in turn specifies the site of division and septum formation. However, it is still unclear how microtubules sense space and provide the cell with positional infonnation. Recently a kinase, Pom1p, enriched at both cell ends and the cell centre, has been shown to play a role in positioning and marking sites of growth and division, probably by regulating microtubules dynamics. The aim of the proposed work is to better define the role played by Pom1p in providing this spatial information. I will perform a suppression screen to identify components lying in the same pathway as PomI p kinase. This screen will allow the identification of targets and regulators of Pom1p, as well as proteins required for Pom1p localization. The requirement for Pom1p kinase localization and regulation will be further investigated by a structure-function analysis of Pom1p protein. I will also investigate the conservation of the components of this system in other model organisms, such as Drosophila melanogaster. The proposed project combines a wide range of cell biological and genetic approaches to issues cell polarization and morphogenesis in fission yeast and will therefore allow me to acquire familiarity with the system which provides a powerful tool to address cell biological issues in eukaryotes. This knowledge will be essential for carrying out the proposed work and also in my future independent carrier. As I am interested in understandin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'PAn-European Clusters for Technology Transfer and new VAlue chains'.

assistant: **Concept**

The overall concept of the project consists of supporting innovation in SMEs and fostering the smart reindustrialization of Europe by enabling the emergence of new cross-border and cross-sectoral value chains resulting from the translation of advanced technologies among selected sectors with strong synergies. These new value chains will be created from the interaction of the following sectors: aerospace, agro-food sector, Health & medical devices and ICT. The project will take of 36Months. The development of the new value chains will be facilitated setting up geographical poles of activity in different regions across ES, PT, NL, IL and PL, comprising: Cluster/ SME intermediaries, which help create an appropriate innovation ecosystems; RTD centres. which are able to assess the potential and viability of the proposed new value chains for SMEs innovative services or products. Besides, the third kind of entity, the innovation facilitators will operate at a cross-cluster level, organizing funding rounds to complement with private funds EU public support and establishing networks for collaboration. More than 50 letters of support signed by a different type of stakeholders.ACTTiVAte will undertake 2 kinds of activities to optimize the benefits to SMEs: a)Direct funding of SMEs innovative projects. Competitive calls will be launched in the proposed technology areas. The winning projects (50) will be selected and an overall amount of up to 46.000€/each SME from a total of a 1,5M€ from the project budget. The selection criteria will consider both the technical feasibility and viability and the socioeconomic impact. b)Activities aimed at creating a favourable environment for the innovation in those SMEs participating in projects selected in the call for proposal processes, such as
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'In vivo Immunofluorescence-Optical Coherence Tomography' to be submitted under Horizon Europe.

assistant: **Abstract**

Current clinical medicine relies on MRI and CT for structural imaging, and immuno-PET/SPECT for molecular specificity. The combination of structural imaging and molecular specific imaging provides detailed information about expression of proteins and cell surface receptors in vivo in humans. PET-CT/MRI has become an essential component of personalized medicine. However, the resolution of MRI/CT is just under a millimeter, while the resolution of PET is limited to about 2-10 millimeters, insufficient for early disease detection. Moreover, PET is associated with radiation burden of ligands labeled with a radiotracer and can image only one labeled ligand at a time.What is missing is the ability to image in vivo with much higher resolution, and to image multiple molecular targets and molecular interactions simultaneously. I propose to develop the optical equivalent of PET- CT/MRI with a 10 to 100 fold better resolution. To reach this goal I will integrate three-dimensional endoscopic Optical Coherence Tomography (OCT) for structural information with depth resolved imaging of fluorescently labeled monoclonal antibodies for molecular specificity. To image the hollow organs accessible by endoscopy, I will develop the immuno-OCT technology integrated with miniature motorized catheters and the multi-fiber detection technology for depth resolved fluorescence determination for endoscopic immuno-OCT in catheters as small as 1.5 mm diameter. I will focus on esophageal cancer and lung disease. The proposed research has a much broader impact, creating a platform to study in detail therapy-tissue interactions longitudinally in vivo in patients, providing in vivo information approaching immunohistochemistry analysis. This approach will revolutionize the diagnosis and treatment of patien
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Development of an innovative alternative to the use of hexavalent chromium in the aerospace coating' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

The aerospace coatings industry has been working to minimise the exposure of individuals with the sector from Carcinogenic Mutagenic Reprotoxic (CMR) compounds such as hexavalent chromate based coating solution. The drive has been steered towards substituting or at least limit to the bare minimum CMR compounds according to European Directive 2006/122/EC and the European Registration Inspection (REACH) requirements.As Mapaero SAS, a French manufacturer of water based aerospace paints and coating products, we have developed turnkey innovations for the aerospace coatings sector. We have developed a water based primer P7X that is free of the CMR classified hexavalent chromate corrosion inhibitor base in compliance to the Directive 2006/122/EC and REACH requirements. Since our primer is chromate free, we have also developed an effectiveness assessment test Droplet Test, used together with the conventional Salt Spray Test.Our innovation will result in a quick drying, chromate free water based primer that can be easily sprayed onto large aerospace parts with a long pot life >4hours and reduced Volatile Organic Compounds (VOC) constituent limited to <350g/L. Our Droplet test will reduce primer effectiveness validation test from 3,000hours to 168hours. We anticipate this will inevitably result in the establishment of a new standard in the effectiveness assessment of chromate free aerospace coating solutions.The main objective of this Feasibility Study is to initiate and validate the primer qualification for commercial development according to aerospace regulations and define the best strategy to reach market readiness. As a result of this project, we anticipate that we will grow our turnover of €20.82 million and a profit of €12.22 million, increase the headcount by 40 and achie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'ThermoformAble, repaIrable and bondable smaRt ePOXY based composites for aero structures' to be submitted under Horizon 2020.

assistant: **Abstract**

With strong growly rates of 13% in the aero sector, and demands predicted to be doubled by 2032, carbon composites (CC) are under the spotlight. CC production requires a quick ramp-up that needs to be based on robust materials & processes and a solid manufacturing supply chain, where higher production rates and cost reduction are essential. The aim of AIRPOXY is to reduce production & MRO costs of CC parts in aeronautics by introducing a new family of enhanced composites that preserve all the advantages of conventional thermosets, while showing new unprecedented features such as Re-processability, Reparability and Recyclability. This will be possible through further development & validation of a family of ground-breaking thermoset resins (recently invented/patented by CID) including dynamic bonds which enable such smart behaviour. Conversion of the technology from TRL3 to 5 will be achieved in AIRPOXY, through 2 representative demonstrators of aircraft panels. Thermoforming processes previously unthinkable for thermosets will reduce manufacturing cost of CC parts by35% vs autoclave, reducing processing times from hours to minutes. Faster/cheaper repair technologies, in combination with SHM, will reduce significantly MRO costs. Additionally,   a  novel welding process will reduce CC bonding costs by up to 50%. Such new features will foster competitiveness & sustainability in the European aeronautics sector. AIRPOXY relies on a multidisciplinary consortium of 11 partners from 6 countries; CID as resin inventor, key technology providers IVW (thermoforming & welding), EUT(RTM), COEX(SQRTM), UOI(SHM); AEF (process simulation software), aircraft components manufacturers (EIRE, IDEC, SON), standardization experts (UNE) & an aeroconsultancy (ART). They will be supported by a st
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'A FIWARE-based SDK for developing Smart Applications' in the context of a Horizon 2020 call.

assistant: **Objectives**

SmartSDK aims at creating a sustainable FIWARE ecosystem between Europe and Mexico by leveraging on existing FIWARE outcomes and building reference standards for common challenges. To fulfil this goal, SmartSDK will analyse successful FIWARE applications deployed in Europe and derive from these applications a set of FIWARE-based reference service architectures and reference data models to support the agile development of smart solutions for sustainability challenges of today world. In this perspective, SmartSDK will adopt existing Open Standards and Open Source solutions leveraging on results of European and Mexican initiatives based on FIWARE. By “standardizing” these efforts in a reference Software Development Kit (SDK) for smart applications, SmartSDK will foster a long-term collaboration between Europe and Mexico on FIWARE building on shared societal and economical challenges in Europe and Mexico. The collaboration will promote increased FIWARE adoption in Mexico as ecosystem for developing smart solutions, through the involvement of cities, innovative SMEs and startups. This will insure a wide impact in Mexico and Europe and will support the growth of new FIWARE-based businesses through the direct involvement of a network of around ICT 30 incubators and accelerators with access to more than 1000 ICT Innovative companies and startups and the support of Wayra Mexico (owned by Telefonica), the local branch of the worldwide largest accelerator.The participation of key FIWARE partners in Europe (TID, CREATE-NET) and Mexico (INFOTEC, ITESM), the support of European startups building on FIWARE technology (HOPU, UBI), and Future Internet researchers from Mexico (CECISE, CENIDET, INAOE) under the experienced guide of R&D consultancy specialist and key promoter of FIWARE int
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Vehicle Thermal Management', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The ability to bring new vehicles to market rapidly is a major determinant of competitive advantage within the world automotive industry. Vehicle thermal management is an area of increasing importance in new vehicle product development, consuming significant resources and constituting a large proportion of the total time-to-market. Ricardo are leading a European Consortium (VTHERM) to develop new Computer Aided Engineering (CAE) methods in this area of the design process to provide a competitive advantage in the form of substantial reductions in the time-to-market for new products. In brief, the objectives of the project are to develop CAE thermal management software which will:  Deliver substantial benefits in the time-to-market of new vehicles (of typically at least 4 months).  Provide fuel savings through engine cooling system efficiency gains made possible through the use of this technology.  Improve the durability of engine compartment electronics modules (such as engine management systems) by reducing under-bonnet temperatures by at least 10 C.  Contribute to the achievement of EU noise and emission legislation through engine encapsulation and fast warm-up catalyst systems. The major innovation from this project will be the capability to rapidly generate and solve detailed CFD models of the engine compartment and external flow, coupled with a thermal system model of the whole vehicle. This will be possible from:  The use of combined feature-based solid and surface CAD modelling to define vehicle and powertrain geometry.  Fully automatic mesh generation for complete engine compartment and associated external flow CFD solution direct from a variety of CAD geometry sources. Typical model sizes of 1,000,000 computational mesh cells and greater are expected.  The const
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Prevalence and determinants of childhood asthma and allergies across europe' (PDCAAE).

assistant: **Innovation**

The objective of this proposal is to estimate the variance of childhood asthma and allergies across Europe and to assess the relation with known and suspected risk factors for these diseases within and between study centres. Data and specimens from studies that have been conducted in a standardized way according to a common study protocol incommunity random samples of 9-11 year old children in 13 countries and 15 study centres (at least 200 per centre) will be analysed. The proposal applied for funding of collaborative laboratory analyses which include measurements of serum IgE levels, of indoor exposure to allergens and endotoxins, and of genetic markers of childhood asthma. funding is also sought for central data collation and statistical analyses. The project will deliver a pan-European database on the prevalence of childhood asthma and allergies and investigates potential determinants and interaction with genetic background.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Developing and combining technologies for the treatment and recovery of dyehouse waste water sources' in the context of a Fourth Framework call.

assistant: **Objectives**

The Feasibility Study has shown that there is significant interest amongst textile processing companies in the EU for reliable cost-effective compact water recycle plant. In countries where water and sewerage are costed by processors on a volume rate of use basis, recycling can reduce overhead costs of the business by-a significant margin. For processors in other regions, there may be a lack of water resources leading to interrupted supply which is an important motivator. Any volume reduction should be accompanied by COD and colour reduction in order to effect environmental improvement. and possibly to avoid breach of consents for discharge. A combination of filtration and regenerable adsorbent acting as pretreatrment to reverse osrnosis is effective in achieving these requirements. Experience has shown that equipment must be tested under actual factory conditions and that trials must be of extended length due to the longer-term effects of effluent upon treatment systems. It is recommended to conduct trials of 12- 18 months' duration at factory sites using the combination of technologies listed above and to provide flexibility in the construction of the pilot plants to allow modifications to be made in the light of experience and developing best practice during the project. Specific action is recommended to investigate the issue of recycle water quality in respect of dyehouse performance in order to research optimum plant configuration.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Transcriptional reprogramming of Clock at Shoot Apical Meristem in regulating plant organogenesis and growth.'.

assistant: **Innovation**

Plant growth and organogenesis are coordinated by stem cells located in specialized tissues known as meristems. Virtually all the aerial parts of the plant derive from stem cells located in niches at the shoot apical meristem (SAM), where they process internal and external cues to sustain their function. As cells are continuously produced at SAM, it is essential for plants to precisely regulate the timing of proliferation as development and plant organogenesis occurs over time throughout the life cycle. The circadian clock is the primary timing device that enables an organism to measure the pass of the time to precisely coordinate biological activities with the internal cues and its surrounding environment. Despite the importance of stem cell function, the mechanisms controlling the timing of SAM activity in synchronization with the environment remain essentially unknown. we propose to investigate the role of the circadian clock as a flexible biological metronome orchestrating the SAM activity in plants. The Clock-SAM proposal aims to generate a road-map of clock function, defining circadian similarities and divergences among the different functional states at the SAM and establishing the correlation between the circadian pace of the clock and cell fate and specification. We will follow an ambitious integrative approach combining epigenetic and transcriptional regulatory mechanisms to understand stem cell function. Our studies will thus answer a fundamental question in plant cell biology by determining how the plant is temporally constructed in our rotating world. The results from this proposal will provide a framework that can be tested for regulating plant productivity and survival in different environmental conditions. Hence, in the long term our findings could be ap