RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Exploring thioalkynes potential in gold catalysis with a divergent reactivity manifold', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

THIODIV brings together the complementary expertise of Dr Nagnath More (NM, expertise in oxidative reactions and arylation processes) with Dr Paul Davies (Host, expertise in gold catalysis and sulfur-based reaction development). Gold catalysis attract significant international interest due to its ability to generate metal carbene character from alkynes delivering more sustainable synthesis. Current strategies to address the major challenge of site-selective carbene formation use terminal alkynes, or those with strongly electron-donating- or electron-withdrawing groups. Limitations derive from the gold carbenes environment and its impact on reactivity, or the incorporation of undesired directing groups. THIODIV will study the potential of sulfur-substitution to deliver complementary directing effects while introducing a desirable functional group into the resulting molecule.  Preliminary studies show that sulfur can enable gold-catalysed reactivity, yet propose different directing-modes which lead to different regiocontrol. The overall aim of THIODIV is to examine the role of sulfur substitution on alkynes in gold catalysis and clarify its influence on reactivity, and hence allow wider application of sulfur-directing groups in gold catalysis and synthesis more widely. A diversity-generating dynamic reaction manifold will be used to elucidate key control parameters by studying two approaches, an oxidative rearrangement, and an arylative rearrangement. Alongside insight into reaction control and directing effects, THIODIV will provide new and efficient access to motifs that are featured in numerous bioactive compounds and are highly desirable in industry and academia as synthetic intermediates. While addressing fundamental questions of reactivity and control, THIODIV will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Innovative combined material, production and fatigue design concepts for economic high-performance structural powder metallurgy components' (HIGHPER-PM) under Fifth Framework.

assistant: **Objectives**

The project addresses the Powder Metallurgy sector in the objective of expanding the limits and durability of structural materials. This extension will be into mass production of high-density, high-duty components for gearboxes of automotive transmissions and of power tools. The starting powders will be of iron and of atomised master alloys, of compositions developed within the project. The problem of acceptance of PM as a reliable, reproducible production route by designers will be tackled by the development of a design methodology for high-duty PM parts, through the use of rolling contact fatigue data. Processing of recyclable materials with improved mechanical properties will be associated with environmental compatibility and minimising of pollution.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Understanding the Origin of Species: Ecological Genomics and Transcriptomics on Oceanic Islands' (ORIGENE).

assistant: **Innovation**

The origin of species diversity has challenged biologists for more than two centuries, but despite the large amount of literature on the subject, pivotal questions about speciation remain unanswered. For example, we know that the origin of species must involve genetic separation, most often followed by phenotypic differentiation. Geographic isolation and subsequent genetic separation gives rise to the uncontroversial allopatric mode of speciation. But in theory, populations can become genetically separated without geographical isolation, resulting in the more disputed sympatric mode of speciation. Recently, Savolainen (the applicant of this proposal) and colleagues provided strong evidence for sympatric speciation in a case study of two species of Howea palms on Lord Howe Island, Australia. Here, we will take our research to a much deeper level and tackle novel themes. Innovative approaches will be developed, combining field ecology and genetic modelling, and taking advantage of the most recent advances in genomic technologies such as ultra-high throughput sequencing provided by the Roche 454 and Illumina Solexa platforms. Using Howea as a model system, sequences of their transcriptomes, scans of their genomes and genes expression profiles, we will test the theoretical predictions that only a few genetic loci controlling key traits are necessary for rapid ecological speciation. Extending this study to other taxa and islands, we will ask what combinations of ecological conditions and genomic architectures lead to the evolution of new species? Particularly, how can species originate in the face of gene flow, for example when confined to a minute oceanic island? The project will provide one of the most comprehensive studies of speciation and has the potential to provide a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Virus-like particles in plasmodium - a potential role in the evasion of the mosquito immune response' (1994-1998).

assistant: **Innovation**

Research objectives and content Plasmodia are mosquito-borne protozoa which cause malaria. For successful transmission, the protozoa must evade the mosquito immune response. Insect endoparasites (endoparasitoids) suppress the immune system, specifically the encapsulation response, of their insect hosts by utilising viruses and virus-like particles (VLPs). Plasmodia are also known to contain VLPs, exclusively during stages of its lifecycle which occur within the mosquito vector. Morphological, cytochemical and molecular characterisation will reveal the true nature of the VLPs within Plasmodium and provide the basis for the assessment of their role in immune evasion. Training content (objective, benefit and expected impact) Dr.Brey's research group at the Pasteur Institute, which is currently researching the molecular biology and biochemistry of encapsulation within the anopheline malaria vectors, provides a unique opportunity to carry out this proposal. In addition, the extensive expertise in microbiology at the Pasteur Institute, especially in the fields of electron microscopy and virology will give me an opportunity to learn new techniques and explore novel approaches to the study of the parasite-vector relationship. Collaboration with this research group would allow me to broaden the knowledge of vector-parasite interactions acquired as part of my PhD and explore novel mechanisms to combat malaria through the application of a challenging new approach. Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Development of Selective Carbohydrate Immunomodulators Targeting C-type Lectin Receptors on Antigen Presenting Cells' (IMMUNOSHAPE) targeting Horizon 2020.

assistant: **Abstract**

IMMUNOSHAPE aims at training a new generation of scientists that will be capable of combining state of the art synthesis and screening technology to develop new lead structures for highly selective glycan based multivalent immunotherapeutics for the treatment of cancer, autoimmune diseases and allergy. To this end, we have set up a training program in a unique academic-industrial environment that will educate young researchers in scientific and practical biomedical glycoscience with the final aim to produce new talent and innovation in the field and improve their career perspectives in both academic and non-academic sectors. The unique combination of 10 academic groups with expertise in automated solid-phase carbohydrate synthesis, microarray based highthroughput screening technology, tumour immunology, structural glycobiology, multivalent systems and medicinal chemistry along with 4 industrial partners active in nanomedicine, immunotherapy, medicinal device development and the fabrication of scientific instrumentation will provide a multidisciplinary and multisectorial training to 15 ESRs in biomedical glycoscience and its industrial applications.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Probing the long-term forcing mechanisms of the Asian Monsoon by magnetic analysis of aeolian dust in sediments from the North Pacific Ocean' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Understanding past climate change is crucially dependent on understanding oceanic and atmospheric circulation. The atmospheric contribution to paleoclimate is poorly constrained, especially on long (orbital) timescales that might provide meaningful information about the forcing mechanisms of major atmospheric components such as the monsoons. Aeolian dust preserved in deep-sea sediments provides an excellent means of determining past variations in continental paleoclimate and atmospheric circulation.  Previous studies have focused mainly on sedimentologically determined variations of clay and quartz concentrations in aeolian dust. Direct comparison of dust records among different ocean cores and between the North Pacific Ocean and the Asian continent is hampered by poor age control and by poor data resolution from marine cores. Sediment magnetic parameters can efficiently provide high-resolution data for reconstructing paleoclimatic fluctuations.   This project aims to detect systematic spatial-temporal variations in magnetic parameters as proxies of the Asian aeolian dust flux recorded in North Pacific marine sediments along a downwind longitudinal transect over the last several million years. Age models will be determined by a combination of relative paleointensity, oxygen isotope and paleomagnetic reversal stratigraphies. Paleoclimatically controlled variations in grain size and concentration of magnetite, hematite and goethite will be quantified and interpreted along with constraints from non-magnetic parameters (e.g., oxygen isotopes, Ti/Al ratios). We aim to detect how terrigenous dust flux is controlled at the full range of orbital periods. In turn, this will provide important constraints on the forcing mechanisms that drive atmospheric circulation and the Asian M
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Environmnental stresses in a scleractinian coral-dinoflagellate symbiosis: a genomics approach' under Seventh Framework.

assistant: **Concept**

The continued development of M. Pernice as an independent researcher in marine science ultimately depends on his building a strong scientific background and a network of colleagues who are both international in representation and have multidisciplinary expertise. Pursuing a fellowship with an Outgoing phase in the Centre for Marine Studies (Australia) and Return phase in the UMR 5178 (France) offers the unique opportunity to create such a synergy between the experience in research on both climate change and symbiosis.  The great success of corals as ecosystem engineers lie in their extraordinary ecology and physiology that is based on a mutualistic symbiosis between a photosynthetic dinoflagellate algae (zooxanthellae) and the anthozoan animal host. Within the last several decades, scleractinarian corals have been affected by the phenomenon of mass coral bleaching, caused by the breakdown of the symbiosis between the cnidarian host and the photosynthetic symbiont and undergo a continuous global degradation in relation to global climate change.  For the first time, this project proposes to specify the effects of elevated temperature and ultraviolet light on the transcriptome of the symbiotic complex between the coral Acropora millepora and the zooxanthellae Symbiodinium sp. The effects of environmental stress on both host and symbiont genes’ expression will be characterised by using cDNA microarray, RT-PCR and Fluorescent In Situ Hybridization technics. By facilitating a multidisciplinary integrated approach (Climate change, Marine sciences, Physiology, Genomics) of the study of the marine organisms and their ecosystems, this study will enhance considerably the scientific excellence of the fellow at an international level. The postdoctoral training delivered by this proj
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Engine Module Validators' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The ENOVAL project will provide the next step of engine technologies to achieve and surpass the ACARE 2020 goals on the way towards Flightpath 2050. ENOVAL completes the European 7th Framework Programme (FP7) roadmap of Level 2 aero engine projects. ENOVAL will focus on the low pressure system of ultra-high by-pass ratio propulsion systems (12 < BPR < 20) in conjunction with ultra high overall pressure ratio (50 < OPR < 70) to provide significant reductions in CO2 emissions in terms of fuel burn (-3% to -5%) and engine noise (-1.3 ENPdB). ENOVAL will focus on ducted geared and non-geared turbofan engines, which are amongst the best candidates for the next generation of short/medium range and long range commercial aircraft applications with an entry into service date of 2025 onward. The expected fan diameter increase of 20 to 35% (vs. year 2000 reference engine) is significant and can be accommodated within the limits of a conventional aircraft configuration. It is in line with the roadmap of the Strategic Research and Innovation Agenda for 2020 to have the technologies ready for “Optimised conventional aircraft and engines using best fuel efficiency and noise control technologies”, where UHBR propulsion systems are expressively named as a key technology. ENOVAL will be established in a consistent series of Level 2 projects in conjunction with LEMCOTEC for core engine technologies, E-BREAK for system technologies for enabling ultra high OPR engines, and OPENAIR for noise reduction technologies. Finally, ENOVAL will prepare the way towards maturing the technology and preparing industrialisation in coordination with past and existing aero-engine initiatives in Europe at FP7 and national levels.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Soil ecological and economic evaluation of genetically modified crops', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

The possible use of GM plants in future agriculture needs in-depth investigations of ecological and economical consequences. Following state-of-the-art ecological risk assessment we combine simple lab tests, multi-species model ecosystems and field studies to acquire mechanistic and realistic knowledge. Hitherto this has not been done for soil. The investigation will give an important input to the administrators of Directive 200l/18/EC Annex II, who needs specifications of how to do the GM risk assessment, and to farmers and the public who are on the alert to the possible ecological implications. Economic aspects need to be clarified to enable an assessment of trade-offs in relation to ecological effects. The accumulated experience in the ECOGEN project will then be taken one step beyond a simple comparison of GM based farming systems and conventional systems, by combining soil ecological studies with an economic evaluation at the farm level in a rule based model as a decision support tool.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Building a biological knowledge-base on fish lifecycles for competitive, sustainable European aquaculture' to be submitted under Seventh Framework.

assistant: **Abstract**

LIFECYCLE (14 partners, 9 countries) will deliver a knowledge-base to improve competitiveness and sustainability of European aquaculture, through a combination of question-problem driven approaches. The focus will be on early developmental events, growth and environmental adaptation throughout the lifecyle, and on the physiology and immunology of key life-stage transitions, such as metamorphosis, smoltification and puberty.  To advance current knowledge on mechanisms governing essential biological functions in fish, state-of-the-art physiological research will be combined with functional genomics by leading European research groups. LIFECYCLE will focus on all major life stages of sea bass, sea bream, Atlantic salmon and rainbow trout. For these important aquaculture species, substantial resources and biological information exists which will be exploited and integrated to potentiate the overall impact. Two key conceptual approaches will be taken: 1. Changes in physiological systems at different points during the lifecycle will be studied to establish how early factors impact on later stages. 2. Cross-cutting experiments will address integration and crosstalk between physiological systems.  LIFECYCLE is planned to direct research at current production bottlenecks. The knowledge generated about development and growth, adaptation and homeostasis, the immune system, sex differentiation and puberty will have a major impact on alleviating problems linked to abnormal larval development, skeletal deformities, poor growth and energy utilization, mortalities related to life stage transitions, poor environmental performance, and unwanted sexual maturation. The focused dissemination of such knowledge will make the EU aquaculture industry more efficient and stimulate its sustainable
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'ZEP15' (ZEP15).

assistant: **Concept**

The objective of the ZEP15 proposal is to provide support to the development and communication of policy messages of the European CCS community (represented by European Technology Platform ZEP (ETP-ZEP)). Support will be given to the internal organizational and administrative processes within ZEP in order to enable ZEP to carry out activities that are beneficial to the European CCS community, as well as to externally oriented communications activities for bringing the messages of ZEP to the European CCS community.


**Keywords:** CCS ZEP Carbon Capture and Storage
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Female Bodies in Sacred Spaces: Re-evaluating Women’s Agency in the Greek World.' (FemBod), addressing dissemination and exploitation.

assistant: **Impact**

The project aims at re-evaluating womens agency in the Greek sacred world through the application of an innovative and interdisciplinary approach encompassing cognitive archaeology. The role of women in Ancient Greece has been either overlooked or described as powerless, controlled and excluded by scholars (Hogbin, 1970; Spain, 1992). This research overturns this narrative by revealing evidence of powerful female agency in the Ancient Greek sacred space through a cognitive reading of the historical context and ancient mind which will also explain the reasons why women were highly involved and how their agency was fundamental for successful rituals.


**Keywords:** Cognitive Archaeology