RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Error-prone protein synthesis in fungal pathogens Microsporidia: its scope and potential therapeutic targeting' to be submitted under Horizon 2020.

assistant: **Abstract**

Microsporidia are ubiquitous and poorly treatable eukaryotic obligate intracellular pathogens that threaten human health and industrMicrosporidia are poorly treatable eukaryotic pathogens that threaten human health and industrially valuable insects, fish, and cattle. Despite Microsporidia being recognized as emerging pathogens that require development of new drugs, many aspects of their biology remain totally unexplored due to a lack of appropriate genetic tools and because only a handful of laboratories in the world can grow and manipulate Microsporidia in infected host organisms or cell cultures. This proposal involves a promising scientist with a background in biochemistry and molecular biology and who will move to a host laboratory in Newcastle University, UK – a renowned center for excellent training of young researchers, and a leading research center in the field of pathogen evolution. The researcher will undertake a multidisciplinary investigation, combining microbiology, proteomics, and molecular biology, in order to investigate how Microsporidia diversify their proteomes through error-prone protein synthesis (mistranslation). The researcher’s training at the host laboratory – in cultivating and manipulating Microsporidia in mammalian cell lines for proteomic and toxicity studies – will synergistically complement the researcher’s expertise in molecular biology of protein synthesis. Completing the project will equip the researcher with a rare, increasingly valuable and transferable skill of Microsporidia experimental biology that will be a key asset in his transition to an independent research career. The project will deliver the first detailed insights into the ability of Microsporidia to produce myriad protein isoforms from their genes as a result of highly ina
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The evolution of the Grassland biome: exploring past events to predict future scenarios' (GRASSLANDS).

assistant: **Concept**

Knowledge of the evolution of the grassland biome throughout the Earth's environmental history is important for the reconstruction of links between diversification/extinctions events and climate. Biomes are now being impacted by anthropogenic environmental change on an unprecedented scale, and one mean of understanding how component species will react is to study the effects of past environmental changes. Hence, understanding the evolutionary history of grassland ecosystems in the context of past biotic and abiotic changes is relevant to the way we will manage them under future environmental change. A new perspective on the history of the grassland biome is beginning to emerge from key developments in palaeontology and molecular phylogenetics that will be integrated interdisciplinary and multidisciplinary in the present project for the first time. GRASSLANDS aimed at understanding the timing and nature of grasslands' most important components, the grass (Poaceae) and daisy (Asteraceae) families, through the combination of fossil data, molecular phylogenetics and computational approaches. The potential contribution of GRASSLANDS to our understanding of the evolutionary history of these families and grassland ecosystems in general is significant and will certainly provide new insights into the rise of flowering plants as the dominant components of almost every terrestrial ecosystems.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project '360° View Control by Eye Movement for Extended Reality' (EyeView360) targeting Horizon Europe.

assistant: **Abstract**

Virtual/extended reality (VR/XR) head-mounted displays (HMDs) provide users with a portal to virtually infinite display space that extends all around them. This has the potential to revolutionise work, learning and leisure activities as users can enter personalised spaces from anywhere via their HMD to access 3D data, views and apps all around in 360°. However, full use of the surrounding space is only possible with extensive head and body movement as HMDs are head-coupled – prohibiting access in crowded or constrained spaces, causing neck strain during seated use, and excluding users with limited neck mobility.The EyeView360 project will develop a proof-of-concept for a radically new idea for view VR/XR view control by eye movement – providing users with a new super-power of looking all round in virtual space from seated positions without neck strain. Use of eye movement for view control is highly innovative and challenging as it overlays the use of our eyes for seeing with a control function that manipulates our view. Basic principles for how this may be possible have been observed in the ERC Advanced Grant GEMINI, and the goal of EyeView360 is to demonstrate usability, efficiency and ergonomic benefits of view control by eye movement.  The project will develop the innovation potential through an open access toolkit designed to be customisable for uptake across VR/XR platforms, HMD devices and applications. In addition, it will develop a complete proof-of-concept for 360° video viewing as specific application use case. This will be used for extensive testing with users to validation of usability, efficiency and quality of experience.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'CLEANING WITH SOUND IN HIGH TEMPERATURE FACILITIES' (1994-1998).

assistant: **Innovation**

The aim of the project is to demonstrate, verify and establish the method of cleaning by sound, audible as well as infra-sound, in high temperature (1000-1400°C), solid fuel fired power plants, to achieve improved performance through automatic, continuous sonic cleaning.1. Sound cleaning has been used up to 1000 °C but never above that temperature, By using new combination of material, it will be possible to operate in higher temperature.2. Superheater and further down in the furnace.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Telomere instability and the formation and transmission of radiation induced DNA damage'.

assistant: **Concept**

The new insights in telomere maintenance and telomerase activity as keypoints in tumour. The increased knowledge in induction and repair of DNA damage have raised large concern in the link between two process. TELORAD aims to determine the mechanistic link between telomerase, telomere binding protein and DNA repair gene and their respective role in the radiosensitivity. Mechanisms of stabilisation of the broken end, start point to the transmission of the radiation induced damage will be studied. Long term consequences as gene amplification and chromosome imbalance will be researched to identify the involvement of telomere maintenance in Hypersensitivity of individuals.TELORAD shows that telomere radiosensitivity and telomere capping are significant steps in the formation and transmission of radiation-induced damage. Clear associations with DNA damage response and tumour development are emerging in respect of chromosomal instability associated with the structure/ function of the telomeric repeat sequences that cap the ends of chromosomes. Telomere metabolism is closely linked to certain DNA repair proteins and shortening and alteration of telomeres can trigger apoptotic response and/or chromosomal instability and/or amplification via post-irradiation cycles of telomeric fusion-breakage-fusion.1. The telomere length is one of the biological determinants of radiation sensitivity in mammals.2. Human ITS are not hotspots for chromosome breakage; specific chromatin structure could induce such hot spots.3. The analysis of the mechanisms of capping of radiation-induced DNA breaks is crucial for understanding the biological consequences of exposure to ionizing radiation.4. DNA repair gene defects increase the probability of gene amplification.During Telorad project the following
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Territories of incarceration. A comparative study of prison farms in rural Europe and a proposal for Flanders.'.

assistant: **Concept**

A Prison Farm (PF) is a correctional facility located in rural environments where inmates are employed in open-air manual work.Within the current European carceral archipelagos, mostly constituted of mass urban walled prisons and recent suburban super prisons, PFs are limited in number and scope and often disregarded by national and EU policies, and by academic studies. Yet, PFs show potential in addressing the EU's wills to: improve the current state of incarceration while reducing its scope; promote sustainable agriculture and rural development. The IF's objective is to tackle these 2 societal challenges with a pilot project for a network of detention farmhouses that will be tested in the territorial condition of Flanders, a EU region suffering from an increase loss of farms. The project adopts a research-by-design methodology and will follow a groundwork comparative study of the space of selected existing PFs in Belgium, Italy, and Finland, aiming at the acquisition and systematization of a currently missing knowledge on European PFs. The project will be based -while extending its scope to the rural condition- on the cutting-edge institutional model elaborated by the NGO De Huizen, whose proposal for a network of urban small-scale contextually integrated detention houses is challenging the current penal system in Belgium. The supporting network of the host and partner institutions (KU Leuven-Dept.of Architecture, VUB-Dept.of Criminology, De Huizen), and of key members from Belgian public authorities in the sectors of prison and rural development, constitutes a unique interdisciplinary milieu of knowledge and expertise that will guarantee the success of the IF.This will impact the fellow's career, evolving her expertise in the field of prison architecture while expand
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Rural information network gateway' (1998-2002).

assistant: **Innovation**

The Rural Information Network Gateway seeks to examine the state of the art as regards tourism and commerce in rural areas and develop an innovative low-cost, user-friendly system that will enable the dissemination of information and knowledge among isolated rural communities and provide them with an outlet for their goods and services. The RING project will take place in three phases:1. Research and analysis into the requirements of the rural community in terms of diversification of activities.2. Design and development of a communications network application to serve as a unified, standard European link to the needs of developing rural areas.3. Evaluation of the service in three European test sites and exploitation and dissemination of the results. A consortium consisting of user groups, evaluation consultants and technology suppliers will carry out the project that aims to satisfy the requirements of the Common Agricultural Policy in so much as it asks for... a multi sect oral and integrated approach to the rural economy in order to diversify activities, create new sources of income and employment. The project will seek to establish the best methods and tools for the successful integration of new information and communications technologies within an effective framework for rural development and diversification.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Spatio-temporal shaping of electron wavepackets for time-domain electron holography' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Advanced techniques of electron microscopy and spectroscopy require tools, which enable to control various degrees of freedom of electron beams (phase profile, temporal structure, orbital angular momentum, etc.). The inelastic quantum coherent interaction between light waves and electron wavepackets allows to structure the temporal probability distribution of electrons with attosecond precision, which may enable probing the coherent dynamics of optical excitations or plasmonic near-fields of nanostructures and metamaterials. Up to now, only electron-photon interactions mediated by solid-state structures have been considered, which have severe limitations. In this project I will develop a versatile tool for quantum coherent shaping and full characterisation of the phase profile and amplitude of the electron wave function in electron microscopes. The interaction will be mediated by the ponderomotive potential of spatio-temporally shaped light fields in vacuum. The electron wavepackets will be controlled on nanometer spatial and sub-femtosecond time scales that are natural for light waves. The optical coherence imprinted to the electron wavepackets will be exploited in two ways: i) I will explore the possibility to transfer the temporal coherence from density-modulated electron wavepackets to radiation and bound electron excitations in two-level quantum systems by detecting phase-resolved cathodoluminescence and coherent Smith-Purcell radiation driven by swift electrons. ii) I will introduce time-domain electron holography, which will exploit the temporal coherence of shaped electron wavepackets for phase-resolved imaging of optical excitations in nanostructures. The approaches proposed in this project open new pathways for electron-mediated optical quantum-coherent contro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The Consistent Solvency Model for the insurance undertakings in the European Single Insurance Market' (CONSOL-M).

assistant: **Concept**

The project CONSOL-M focuses on the solvency requirements of the insurance undertakings functioning within the European Single Insurance Market (ESIM). Currently the solvency of an insurer is examined by the supervision authority only in relation to the qu antifiable risks, i.e. financially measurable risks (= a solvency margin on top of the technical provisions). The other risk categories (the qualitative risks) such as the capital investment risk, the corporate governance risk, the internal control quality , the risk management as well as market disclosure are not taken into account so far. However we believe these qualitative aspects have a considerable influence on the overall solvency position of the insurer. It implies that an overall risk-based solven cy model does not exist yet. Therefore, to maintain the stability of the European insurance market, there is an urgent need to establish a new consistent solvency framework for the insurance companies across the enlarged European Union. The principal objec tive of CONSOL-M is to develop an all-risk-based solvency model and to compare and measure the impact of imposing such standards on the ESIM. In order to realize this scientific project two goals are distinguished: to develop a theory on how to build and e valuate a consistent solvency framework regarding all risks determining the overall financial situation of the European insurer, to measure the economical consequences with respect to both consumer - and shareholder protection as well as market stability ( multi-parties point of view).The novel situation is of essential meaning for the further establishment and coordination of the integrated solvency supervision model within the enlarged ESIM. The results of CONSOL-M will allow better match solvency require ment
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'KNOWLEDGE ASSURANCE IN MULTIMEDIA PUBLISHING' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

KAMP is to develop and test distributed teleservices for delivering multimedia training sessions in the sector of interactive multimedia publishing. Five universities will provide interactive modular training based on different courses, with support from case-study learning materials. The system will mainly address the individual needs of university students and staff and professional trainees working together in widely separated groups. Most aspects of multimedia products and services, including authoring and design, will be covered and, after validation and demonstration, project results will be marketed across Europe.KAMP will develop and test distributed teleservices for delivering multimedia training sessions in the sector of Interactive Multimedia Publishing.The system will be based on a network of universities delivering modular training which integrates material from different courses. The training delivered will be interactive and multimedia in form as well as content and supported by on-line case-study learning materials. The project will develop the necessary software and content material, validate and demonstrate the system.The end-users are staff, students and former students of the partner universities; and professional trainees, who will receive distant and flexible training through different combinations of course modules according to their experience and needs. KAMP is adapted to the needs of students and trainees studying at home and telematics will deliver courses to registered students irrespective of their geographic location.System content will include taught modules, case study modules, production modules, and the resources required to perform learning activities (multimedia tools, media, data assets, etc). It will cover multimedia authoring and d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Novel Effect biomarkers for MEtabolic disruptorS: evidence on health Impacts to answer science and policy needS'.

assistant: **Objectives**

Endocrine-disrupting chemicals (EDCs) disturb lipid and glucose metabolism in several metabolically active organs such as liver and pancreas besides being able to interfere with many aspects of hormonal action. There is accumulating evidence linking EDCs or their mixtures with an increased incidence of obesity, atherosclerosis, and type 2 diabetes. Developmental exposure to EDCs can exert life-long, even transgenerational effects and affects the susceptibility to many diseases. However, the metabolic effects of EDCs are still poorly understood and the lack of mechanistic data and predictive models of adverse metabolic outcomes of EDCs hinders their risk assessment. The “Novel Effect biomarkers for MEtabolic disruptorS: evidence on health Impacts to science and policy needS” (NEMESIS) consortium brings together experts in toxicology, medicine, risk assessment, and social sciences and humanities to respond to the unmet regulatory needs of EDCs within silico, in vitro, in vivo, epidemiological and systems biology data on EDC-mediated metabolic effects in multifactorial models. We will assess mechanistic data on metabolic disruption in liver and pancreas and how EDCs or their mixtures affect the microbiota, enhanced with data on dose-response relationships and the causality of these actions. In addition, NEMESIS will provide human exposure data of EDCs and explore effect biomarkers for metabolic disruption. NEMESIS’ results will improve assessment of metabolic endpoints in testing guidelines and adopt alternative models to animal testing. Adverse Outcome Pathways (AOP)s and Integrated Approaches to Testing and Assessment (IATA) approaches will be developed to assess adverse metabolic effects of EDCs and improve the risk assessment towards a more holistic approach. Citizens