RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Pan-European forum for nanotechnology' (NANOFORUM).

assistant: **Innovation**

The Thematic Network will provide a comprehensive source of information on all areas of Nanotechnology to the business, the scientific and social communities. The main vehicle for the thematic network will be a dedicated website Nanoforum.org. Nanoforum will encompass partners from different disciplines, bring together existing national and regional networks, share best practice on dissemination national, EU-wide and Venture Capital funding to boost SME creation, provide a means for the EU to interface with networks, stimulate Nanotechnology initiatives in European underdeveloped countries, stimulate young scientists, publicises good research and form a network of knowledge and expertise
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Solving The Entrainment Puzzle' under Horizon 2020.

assistant: **Concept**

As a cloud moves through environmental air, cloudy and cloud free air mix at the cloud edges in the entrainment process. Entrainment is a key cloud process central to understanding cloud morphology and microphysical processes such as precipitation formation. After decades of research, no reliable formulation exists that allows to describe and understand entrainment in terms of cloud- and environmental physical quantities (""the entrainment puzzle""). Differences in representation of entrainment in climate models are a main cause for spread in climate sensitivity estimates. The realistic treatment of entrainment in climate models will help to reduce a large part of the uncertainty in predictions of climate sensitivity.This project aims at Solving The Entrainment Puzzle (STEP):- By identification of the main physical parameters that govern the amount of air entrained into and detrained from clouds using controlled laboratory measurements.- By translating the experimental results into a new mathematical formulation to use in Large Eddy Simulations of clouds using computational fluid dynamics modelling.In a unique approach, STEP will combine observations from a novel turbulent cloud chamber, computational fluid dynamics, and Large Eddy Simulations to  develop a new reliable entrainment calculation scheme. Solving the entrainment puzzle will allow quantifying the entrainment processes reliably and thus deliver the basis for climate model improvements.The STEP project builds on my expertise in cloud microphysics and dynamics gained at various international institutes and will be accomplished at a leading international research institution. The host will provide me with excellent complementary training and career development opportunities. Through various dissemination and com
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Host and microbial molecular dissection of pathogenesis and immunity in tuberculosis' under Seventh Framework.

assistant: **Concept**

Tuberculosis (TB) is a leading public health problem. About half of the 10% of Mycobacterium tuberculosis-infected individuals develop overt clinical disease, do so within two years of primary infection. The remaining half of the TB patients, develop clinical disease later, owing to “reactivation” of pulmonary TB. Of importance, it is not understood why only 10% infected individuals develop active disease. In this project, we will investigate the molecular and cellular interactions between mycobacteria and host cells, and the regulation of such interactions by cellular immune responses. Such interactions dictate the outcome of infection, ranging from asymptomatic infection to life-threatening disease. For this purpose, we have established a consortium of experts in Genetics, Immunology, Microbiology and Paediatrics and a biotechnology company. We will dissect the molecular and cellular immune responses, combining mice models, and human patients. In both approaches, the responses of various host target cells regulating mycobacterial growth and the mycobacterial adaptation to different host cell responses to infection will be studied. The role of innate and adaptive immune responses in the control of mycobacterial growth and the regulation of inflammation will be studied as well. In addition, we will investigate such responses using a third model based on mice reconstituted de novo with human hematopoietic-derived cell lineages. Finally, targeted and genome-wide explorations will be employed in large familial samples to identify novel susceptibility genes involved in the immune control of primary M. tuberculosis infection and secondary pulmonary TB. The outcome of HOMITB will be an assessment of molecular and cellular interactions crucial for the design of novel vaccinati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'From stem cell technology to functional restoration after spinal cord injury' (RESCUE).

assistant: **Innovation**

Spinal cord injuries (SCI) have long been regarded as intractable, largely due to the alleged inability of the mammalian CMS to regenerate. However, over the last two decades, technological advances combined with the understanding of the pathophysiology of SCI have progressed to the point where it is now conceivable to develop therapeutic intervention strategies aimed at reconstructing the neuronal circuitry damaged by the lesion. One of the most powerful tools for this objective is based on stem cells, whi ch can be used in three different ways to achieve this goal: 1) to bring permissive molecules and/or trophic agents at the level of the lesion to enhance the regenerative capacity of severed axons; 2) to use as replacement cells, grafted locally to stimula te specific circuits such as the central pattern generator (CPG); 3) to enhance the reparative potential of intrinsic stem cells. Most of the program will concentrate on human adult stem cells generated from bone marrow and adult CNS (including the spinal cord), but we will also consider foetal stem cells and established cell lines. Rodent cells will also be used as a model. This program will be achieved in three steps: Harvesting of adult and/or foetal stem cells (neural and non-neural), to be used directl y or after transformation through genetic engineering. Grafting in the injured cord. Monitoring of the grafted cells with in vivo imaging, and assessing their effects using functional studies. It will require several technical prerequisites including stand ardisation for the harvesting of human stem cells, for the spinal cord lesion models, for the transplantation paradigms and for the functional studies. The final objective of the present project is the translation of experimental studies to clinical practi ce
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Joint development of novel anti-diabetic drugs from natural sources by strategic combination of pharmacology and chemistry' (2002-2006) targeting Sixth Framework.

assistant: **Abstract**

About 25 million people in the EU suffer from Diabetes Type 2, causing healthcare expenditures of up to 50 billion Euros per year [IDF]. New effective drugs are urgently needed, as prevalence is growing and diabetes can still not be controlled adequately.  We would like to apply for the Marie Curie Transfer of Knowledge program with a project which aims at the development of novel drugs against diabetes type 2 from natural products by applying an interdisciplinary and promising approach. The main objective of our project is to build a long-term strategic partnership between the academic partner, the MPI-BAC (Germany) and the industry partner, 55pharma (Austria). The partner organisations are complementary: 55pharma will contribute medical, pharmacological, and business expertise, the MPI-BAC will provide expertise in natural products chemistry. Partners will also provide state of the art technology and tools, i.e., 55pharma contributes in-vitro and in-vivo assays, business planning tools and processes. The MPI-BAC contributes state-of-the art equipment such as NMR, MS, GC-HPLC, etc. Close collaboration between pharmacology and chemistry is a key success factor of our project. Building new capabilities will increase the competitive position of each partner. Know-how will be transferred through the exchange of mainly scientists in both directions. The transferees will establish new technologies at the host organisations and train staff, and learn new skills while being part of interdisciplinary research team s. Sustainable impact will be achieved by institutionalization of know-how during the end of the project. Our project meets the program objectives by applying an interdisciplinary, cross-border collaboration and has significant impact for the European Research Area: i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Women, well being, work, waste and sanitation : action research on alternative strategies of environmental sanitation and waste management for improved health and socio-economic development in peri-urban coastal communities in south asia' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

Reuse of night soil and organic domestic waste in agriculture is a common practice in South-east Asia. This is not the case in India, Bangladesh and Sri Lanka. Here, waste is still deposited in public space. The potential to collect, recycle and reuse biologically degradable domestic waste for reuse in agriculture has hardly been explored. Access to proper sanitation is low and sanitation programmes focus on containment and dumping and not recycling. Few peri-urban sanitation programmes use participatory approaches that are gender and poverty sensitive and create employment for women as latrine masons and in solid waste collection and recycling. Multi-disciplinary action research will compare the cost-effectiveness of existing sanitation programmes with innovative approaches that address the above mentioned problems.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Still Connected: Evolutionary implications of the separation of the head from pectoral girdle in tetrapods and their fish relatives' (2007-2013).

assistant: **Innovation**

Separation of the shoulders from the head to create a functional neck was an important step in the conquest of land, as it is crucial for land-living vertebrates (tetrapods) to move their heads freely from the body. The origin and evolution of the neck is currently a research area of considerable interest, with in-depth molecular analysis performed in both the chicken and the mouse (derived tetrapods). What this research shows is that although the shoulders are freed from the head, they are still connected via a network of muscles, and that the development of these muscles is controlled by a specialised group of cells known as neural crest cells. However, comparative studies on this region in fish ancestors, lacking a functional neck, have not been performed. Did these features evolve in response to the separation of the head from the shoulders? Or, are the same muscles and developmental mechanisms present in fish ancestors lacking a neck (head and shoulders connected by a series of bones)? To answer these questions, we will study representatives of more primitive tetrapods and fish ancestors to the tetrapods, including the paddlefish, the Australian lungfish, and the Mexican axolotl. This research will be done in conjunction with project partners in the USA, Australia and Germany. In our experiments, we will use several different types of markers to track migration and development of muscles, neural crest cells, and the skull and shoulder girdle bones, and how these interact during early ontogeny. Our hypothesis is that the results in the muscle connectivity observed in the chicken and mouse will also be present in these fish and tetrapod ancestors, with the involvement of the same (homologous) muscles, and moreover, that neural crest cells will be involved in the deve
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Industrial cooperation across continents' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

GNSS.asia2 engages on pre-marketing activities and business development support for European Industry and EGNSS in the Asian region: GNSS.asia2 is building on GNSS.asia (FP7) which has established the foundations for concrete COLLABORATION BETWEEN EUROPEAN AND ASIAN INDUSTRY with already significant results with India, China, Taiwan, Korea and Japan: -Built an effective team by blending industrial cooperation professionals with GNSS experts -Developed a TOOLBOX of GNSSS communication instruments in LOCAL LANGUAGES-Established an INDUSTRIAL RELATIONSHIP PLATFORM through numerous workshops, seminars, round tables and communication activities -Enabled unique NETWORKING OPPORTUNITIES for European companies to showcase their products in Asia -Facilitated the INTRODUCTION OF GALILEO in Asian industry players’ products -Provided TRANSPARENCY ON ASIAN MARKETS, research input and contacts for GSA and industry -Engaged key GNSS stakeholders in Asia (industry, associations, institutes and gov’t agencies)Industrial collaboration in the GNSS downstream sector is becoming increasingly important as Galileo hits the market and services get tested. Half of the world’s population live in Asia and Asian high-tech companies supply GNSS-electronics to the world. The DIFFERENTIATORS OF GALILEO need to be underlined in the MULTI-GNSS HOTSPOT ASIA. European industry needs support in BUILDING INDUSTRIAL PARTNERSHIPS with Asian companies. GNSS.asia2 will create and deepen industrial relationships, promote EGNSS differentiators in Multi-GNSS, raise EGNSS AWARENESS in Asia. Our proven team will achieve this through PARTNERSHIPS WITH ASIAN GNSS STAKEHOLDERS like the MULTI-GNSS ASIA Campaign and a dedicated GNSS.asia INDUSTRY ADVISORY BOARD.  The proposal is ENDORSED by more than 20 GNSS companies a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Advanced Studies towards Knowledge on Lyssavirus EncephalitisPathogenesis Improving Options for Survival' (ASKLEPIOS).

assistant: **Concept**

The overall aim of ASKLEPIOS is to unravel and increase our understanding of the mechanisms that govern pathogenesis of rabies virus (RABV) infection, in pursuit of the rational identification of novel therapeutic leads for rabies encephalitis. Several studies have been conducted over the past decades attempting to unravel the pathogenesis of this deadly disease, however with limited success. New knowledge on the mechanisms of the RABV life-cycle and interaction with the host is needed to identifying clinically applicable therapeutic leads, in search of rational intervention strategies.  The project objectives are to:1. Identify molecules that inhibit RABV replication2. Identify molecules that inhibit detrimental host responses to RABV infection:3. Show whether opening the blood-brain-barrier (BBB) improves treatment efficacy:4. Validate the potential of the molecules identified under 1 and 2 to be used as post-exposure prophylaxis (PEP) when classical PEP is ineffective.In pursuit of these objectives ASKLEPIOS will perform in vitro screening of the anti-viral effect of type-I IFNs, MAP kinase inhibitors and siRNAs. Second, the therapeutic potential of inhibiting the pyroptotic pathway and inflammatory response will be investigated by using inhibitors of caspase-1, IL-1β, TNF-α IL-6 and MAP kinases. Third, the capacity of molecules to reach the brain will be first evaluated using an efficient in vitro BBB system and in vivo mouse studies.. The most efficient molecule to open the BBB will be co-administrated with the selected therapeutic molecules in the subsequent stages of the project. The results will be collected and synthesized and tested in mice to identify the most effective approach. The ability to clear infection and recover from rabies will be evaluated for eac
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Provision of services for enhancing innovation management capacity of the Cypriot SMEs by the Enterprise Europe Network Cyprus' (KAM2CY4) targeting Horizon 2020.

assistant: **Abstract**

The project envisages the provision of high quality innovation management capacity assessment and support services to SMEs in Cyprus aiming at the enhancement of competitiveness, smart growth and profitability of SMEs. Moreover, the project aims at creating a better understanding of the fundamental principles of innovation management and their better integration in the value chain of local SMEs.The services will be provided by the Research Promotion Foundation (RPF), Coordinator of the Enterprise Europe Network-Cyprus (EEN-Cy) and will be integrated by EEN-Cy services. RPF has already provided relevant services through preceding projects funded by EC (KAM2CY, KAM2CY2 & ΚΑΜ2CΥ3). The project targets two groups of SMEs with a separate package of services, as described below:(a) Provision of Key Account Management (KAM) services to SME-beneficiaries of H2020 SME Instrument, FET-Open & FTI:  - identify weaknesses in innovation capacities of beneficiaries hindering the realisation of growth opportunities and full commercial potential;   - identify coaching needs based on a pre-defined matrix (made available by EASME);  - identify suitable coaches to address the identified weaknesses;   - moderate the coach-client relationship;   - in the case of SME Instrument beneficiaries, accompany the beneficiaries through their projects. (b) Provision of services for Enhancing Innovation Management Capacity (EIMC) to promising SMEs with potential for growth via innovation:  - diagnostic audit/ assessment of their innovation management;  - root/ cause analysis of the results;   - development of an action plan;    - assistance of the SME in action plan monitoring and implementation. The project foresees the provision of 3 KAM and 5 EIMC service packages. The average duration of each servi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Attosecond tracing of collective dynamics  in clusters and nanoparticles' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Collective electron motion can unfold on attosecond time scales in nanoplasmonic systems, as defined by the inverse spectral bandwidth of the plasmonic resonant region. Similarly, in dielectrics or semiconductors, the laser-driven collective motion of electrons can occur on this characteristic time scale. Until now, such collective electron dynamics has not been directly observed on its natural, attosecond timescale. In ATTOCO, the attosecond, sub-cycle dynamics of strong-field driven collective electron dynamics in clusters and nanoparticles will be explored. Moreover, we will explore field-dependent processes induced by strong laser fields in nanometer sized matter, such as the metallization of dielectrics, which has been recently proposed theoretically.In order to map the collective electron motion we will apply the attosecond nanoplasmonic streaking technique, which has been proposed and developed theoretically. In this approach, the temporal resolution is achieved by limiting the emission of high energetic, direct photoelectrons to a sub-cycle time window using attosecond XUV pulses phase-locked to a driving few-cycle near-infrared field. Kinetic energy spectra of the photoelectrons recorded for different delays between the excitation field and the ionizing XUV pulse will allow extracting the spatio-temporal electron dynamics. ATTOCO offers the capability to measure field-induced material changes in real-time and to gain novel insight into collective electron dynamics. In particular, we aim to learn from ATTOCO in detail, how the collective electron motion is established, how the collective motion is driven by the strong external field and over which pathways and timescale the collective motion decays.ATTOCO provides also a major step in the development of lightwav