RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Development of an integrated biorefinery for processing chitin rich biowaste to specialty and fine chemicals' to be submitted under Seventh Framework.

assistant: **Abstract**

The fishing industry in the EU and elsewhere produces an increasing mass of negative value crustacean shell waste (>6 MTPA), whose current disposal in landfills results in significant costs and risks to human health as well as to the environment. While in Asia small amounts of shrimp waste are processed to chitosan, the high CaCO3 content of EU crab shell waste has prevented cost effective conversion to value adding products. The project will develop an integrated biorefinery platform transforming the chemical constituents of EU, African and Asian crustacean shell waste into “drop-in” and novel chemical intermediates to produce high value, high performance bio-based polymers at high atom efficiencies. The innovative process comprises pretreatment steps to facilitate downstream enzymatic depolymerisation and conversion of sugars into chemical building blocks utilizing enzymatic and whole-cell biocatalysis routes. Biocatalyst development requires application of genomics techniques in combination with green-chemical and process-engineering know-how. Sustainable purification technologies will enable integration of monomers into current industrial polymerization processes. Biowaste streams will be valorised for the production of bioenergy to improve process efficiency and greenhouse gas footprint. The environmental impact of the process chain will be evaluated by a cradle-to-product life cycle analysis. Process scale-up will be linked with modelling and optimization studies to demonstrate economic viability. The consortium of 5 academic, 4 SME and 2 large industrial partners has the technical and management expertise to rapidly transfer laboratory scale results into novel industrial product lines at an accelerated pace. Key consortium members are from 5 different EU and 2 as
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Fundamentals of actively controlled flows with trapped vortices' (VORTEXCELL2050).

assistant: **Innovation**

VortexCell2050 will deliver a new technological platform combining the two cutting-edge technologies, the trapped-vortex and the active flow control. The project outcomes will serve the designers of the next-generation thick-wing aircraft. Thick-wing, or blended wing-body, aircraft are identified as prospective for development over the next 50 years in the NASA and FAA commission report 'Securing the Future of U.S. Air Transportation: A System in Peril,' released in September 2003. Success of VortexCell205 0 will ensure European Aeronautical Sector a leadership in a small but critical area, the importance of which will grow in the future with an increase in aircraft size. VortexCell2050 outputs will provide a valuable economical asset for the European Aeronautical Sector thus making the Sector an active player in the niche of trapped-vortex applications.VortexCell2050 exploitation route involves the application of the new technological platform to a relatively small High-Altitude Long-Endurance aircraft. This will demonstrate the opportunities for SMEs created by the new technology.VortexCell2050 final report will include a Roadmap section giving an overview of the step change in aircraft design which can be foreseen on the basis of the technological progress in the trapped-vortex technology. According to certain forecasts, such progress will lead to creation of very large aircraft capable of take-off and landing almost anywhere outside traditional airport, and capable of using gas as fuel. Such a possibility has significant economical, social, and political implications and politicians need to know about them.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Metabolic Adaptation and Resilience in the face of a changing environment' in the context of a Horizon 2020 call.

assistant: **Objectives**

Microbes have evolved to make the best use of their environmental resources while retaining sufficient adaptive capacity to cope with changing conditions. However, even simple changes in the environment require major cellular rearrangements, that manifest in the transcriptome, proteome and metabolome of the cell. For instance, a change in the availability of just four non-essential nutrients affects expression of 2/3rds of all yeast genes. In essence, we do not understand the key molecular mechanisms that govern such huge plasticity, which buffering mechanisms prevent the collapse of the cellular system, and how an optimal resource allocation is achieved to allow cells to thrive in so many environments. In this project, we will analyse a large collection of yeast wild isolates grown in conditions that resemble different ecological niches. We will identify the key molecular pathways that enable environmental adaption. Thanks to unique high-throughput capacities of the host laboratory, I will be able to record proteomes, metabolomes and growth properties of the wild yeast strains. I’ll link these molecular datasets to fitness and metabolism. My background being in big data analysis and network modelling, I will use genome-scale metabolic models and machine-learning to characterize how changes in protein resource allocation impact the distribution of metabolic flux in such context, and define, what are the regulatory mechanisms influencing metabolism at its different levels. Eventually, the knowledge gained will enable me to build a predictive model to understand the drivers of adaptations to ecological niche. By deepening our understanding of the mechanisms behind metabolic niche adaptation, this project will not only answer fundamental questions about the inner working o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Dissecting how the Drosophila brain regulates behavioral sequences of feeding to ensure protein homeostasis' in the context of a Horizon 2020 call.

assistant: **Objectives**

Balanced intake of nutritional amino acids is a key determinant of fitness across animal phyla including Drosophila, mice and humans. Imbalanced protein intake have severe implications for health, lifespan and fecundity. To maintain protein homeostasis, animals evolved physiological, neuronal and behavioral strategies that secure balanced intake of dietary amino acids. Altogether, these strategies give rise to protein-specific appetite where deficiency of a dietary amino acids subsequently triggers increased consumption of food sources rich in protein.Drosophila feeding behavior, like many animals including humans, comprises hierarchically-organized behavioral sequences that are tightly regulated by the protein state of the fruit fly. These behavioral sequences include meals that are organized into feeding bursts composed of multiple sips of the food source (the feeding microstructure). It has been shown that deprivation of dietary amino acids specifically modulate the duration of the feeding bursts to trigger compensatory consumption of protein-rich sources. However, the modulatory pathways and neural circuits that ensure protein homeostasis by regulating the feeding microstructure with such specificity remain elusive.In the proposed project we aim to identify and characterize modulatory pathways and neural circuits controlling protein-specific appetite. To achieve this, we will combine high-resolution behavioral analysis of feeding with unprecedented neurogenetic toolkit of Drosophila to monitor and manipulate activity in defined subsets of neurons. By using anatomical and functional neural-circuit mapping strategies, we will provide a circuit-level explanation for the regulation of behavioral sequences underlying protein-specific appetite.


**Keywords:** Drosophila,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Exploring the mechanisms underlying the evolution of plastids through the study of an unusual nitrogen-fixing symbiosis' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Symbioses are evident sources of innovation in nature, critical for the evolution of plastids and the success of eukaryotes on Earth. The mechanisms promoting such relationships, however, are difficult to identify, especially between single-celled organisms, and remain largely unknown. A widespread symbiosis was recently discovered in the ocean between an unicellular cyanobacterium (UCYN-A) and single-celled eukaryotic algae (prymnesiophyte). UCYN-A lacks typical cyanobacterial features such as the capacity to perform oxygenic photosynthesis, CO2 fixation or the tricarboxylic acid cycle, and must thus rely on the supply of organic matter from the algal host. In turn, UCYN-A shows a dramatic genome reduction with a high specialization in nitrogen fixation, providing fixed nitrogen to the alga. Given the importance of nitrogen for the algal productivity, it has been hypothesized that UCYN-A could eventually give rise to a nitrogen-fixing plastid in a process analogous to the origin of chloroplasts. This project aims to study the UCYN-A symbiosis both from an evolutionary and a functional point of view: First, the identification and characterization of new associations from marine samples at a global scale through molecular techniques will allow a deep comparison of closely-related symbiotic lineages that will help to understand the evolutionary underpinnings of this symbiosis. Second, nutrient incubation experiments of seawater samples over diel cycles will be performed to identify potential factors regulating the carbon and nitrogen exchange between partners to gain knowledge on the host-symbiont coupling mechanisms. For this purpose, metatranscriptomic analysis and electron microscopy combined with molecular probes and quantitative isotopic techniques (FISH-nanoSIMS) wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Understanding insect migration behaviour and pathways using individual tracking and radar', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Migration involves the seasonal movement of large numbers of animals, usually due to shifts in resource availability. Migrants connect habitats and populations, and have significant effects on ecosystem processes. Insects are the most diverse and abundant group of terrestrial migrants, but in comparison to vertebrates, insect migration is poorly studied. In particular, we have little knowledge regarding the migratory pathways of insects, and their flight behaviour and orientation in relation to topographic barriers. Using a combination of state-of-the-art techniques, individual tracking and vertically-looking radar, I aim to identify migratory routes of insects in Europe, and investigate migratory behaviour in relation to topography. This action will be the first to track migrating insects in Europe using individual-based tracking. This unique combination of methods will provide insight into the migratory behaviour of insects at landscape and local scale and provide us with an unprecedented level of information regarding the mechanisms underlying insect migration. The objectives of the work packages in this project are:WP 1: To investigate the influence of radio-transmitters on the flight behaviour of hawk moths in the laboratory. To investigate space-use and flight behaviour of hawk moths in the field. WP2: To elucidate migratory pathways of insects across Europe using individual tracking, and to understand migratory flight and orientation behaviour in relation to topography along these routes. We will also investigate which factors influence individual departure decisions and stopovers en route. WP 3: To investigate flight behaviour and orientation of hawk hawk moths in relation to weather and topography using vertically-looking radar, at key migration bottlenecks, hi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Macroclean - developing novel gel-based technologies for water clean-up' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The management of contaminated groundwater, surface waters and drinking water is a major issue both in the EU and globally, where recent (and historical) industrial, urban and commercial activities have led to the presence of elevated concentrations of a wide range of contaminants in surface- and ground-waters, adversely affecting the health of millions of people. This has been recognised in a number of recent directives (e.g. the Water Framework Directive, the Groundwater Directive) aimed at protecting ground and surface water resources within the EU. However, despite much progress, groundwater and surface water quality is still highly variable across Europe, and there is an urgent need to develop and fully implement forward-looking technologies to clean-up water and keep it free from pollution. In this project we intend to combine innovative biomaterial / gel technologies with nanotechnologies to develop and commercialize innovative products for the remediation or clean-up of contaminated ground and surface waters. A range of permeable composite gels in which nanoparticles will be embedded will be produced and tested for application as water clean-up devices.  Achieving the objectives of the project will benefit to all European citizens, economy, agriculture and industry and will place Europe in a leading position in the area of polymer-based remediation devices and technologies. This is an inter- and multidisciplinary proposal, which will offer a top class young researcher great opportunities to develop her existing skills, acquire new skills in the area of materials, environmental science and nanotechnology and, more specifically, in the area of technologies for remediation and clean-up devices, generate new knowledge and obtain training in transferable skills and t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Bivariational Approximations in Quantum Mechanics and Applications to Quantum Chemistry' (BIVAQUM).

assistant: **Innovation**

The standard variational principles (VPs) are cornerstones of quantum mechanics, and one can hardly overestimate their usefulness as tools for generating approximations to the time-independent andtime-dependent Schröodinger equations. The aim of the proposal is to study and apply a generalization of these, the bivariational principles (BIVPs), which arise naturally when one does not assume a priori that the system Hamiltonian is Hermitian.  This  unconventional approach may have transformative impact on development of ab initio methodology, both for electronic structure and dynamics.The first objective is to establish the mathematical foundation for the BIVPs. This opens up a whole new axis of method development for ab initio approaches.  For instance, it is a largely ignored fact that the popular traditional coupled cluster (TCC) method can be neatly formulated with the BIVPs, and TCC is both polynomially scaling with the number of electrons and size-consistent. No “variational” method enjoys these properties simultaneously, indeed this seems to be incompatible with the standard VPs.Armed with the BIVPs, the project aims to develop new and understand existing ab initio methods. The second objective is thus a systematic multireference coupled cluster theory (MRCC) based on the BIVPs. Thisis in itself a novel approach that carries large potential benefits and impact. The third and last objective is an implementation of a new coupled-cluster type method where the orbitals are bivariational  parameters. This gives a size-consistent hierarchy of approximations to multiconfigurationHartree--Fock.The PI's broad contact with and background in scientific disciplines such as applied mathematics and nuclear physics in addition to quantum chemistry increases the feasibility of the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Theorizing the Drivers of the Asylum-Far Right Nexus in Rural Europe' (Mind-the-NEXUS) under Horizon Europe.

assistant: **Objectives**

Since 2015, mediatised episodes of protest and hostility towards refugees in rural areas in Europe have contributed to the perception of an alleged nexus between reception and the electoral success of far-right populist parties. However, despite the increasing interest of academic research, a patchy understanding of the factors and mechanisms driving the emergence of an asylum-far right nexus in rural areas persists. Whereas public opinion surveys emphasise the nationalistic orientation of rural Europe, research on policymaking has unravelled cases of welcoming and pragmatism.Mind-the-NEXUS will address this puzzle by leading the first systematic and comprehensive study of asylum politics in rural areas that in the last decade have been facing multiple challenges due to the arrival of different waves of refugees in times of reduction of public services (e.g., schools, hospitals etc.). It will do so by focusing on five European countries – France, Germany, Italy, Sweden and the UK – where municipalities represent key actors in reception policy. By adopting an innovative cross-country/cross-locality research design, Mind-the-Nexus will deliver a new understanding of the rural politics of asylum centred on the notion of Rural Political Arena (RPA), intended as the multilevel relational sphere where reception and integration policies take shape. Mind-the-NEXUS will deeply innovate scholarly and policy-oriented debates by expanding our understanding of opposition to refugees and FR politicization in still under-researched rural area. Through a mixed-methods approach combining Large-N quantitative studies on a newly compiled database, qualitative research on no less than 60 rigorously selected RPAs, and the first comparative rural elites survey, Mind-the-NEXUS will generate a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Advanced lightweight materials FOR Energy-efficient STructures' (FOREST) targeting Horizon Europe.

assistant: **Abstract**

The transport sector has always been the focus of decarbonization in Europe. FOREST project proposes to combine the Reduce, Recovery and Reshape” drivers to face the decarbonization issues in the transport sector. Reduce: On the one hand, the greenhouse gas emissions of fuel vehicles and the energy consumption of electric vehicles reduction is one of the major dares of the global mobility sector. FOREST will reduce the structural weight of the vehicles by providing light components made of carbon fibre reinforced plastic. In this way, less fuel and energy consumption will be necessary to cover the same distance. On the other hand, fossil sources are being run out more and more. Besides, their use at the End-of-Life (EoL) has a negative impact on the carbon footprint. FOREST will develop new chemistries based on high-biobased content for polymers (bioacrylic, biobenxozaxine, biopolyamide) and additives (bio fire-retardant). In this regard, the fossil sources' dependency will be reduced. Recovery: The CFRP market is expected to increase more and more in the transport sector (aerospace, automotive, and heavy-duty). However, an important issue which has not totally overcome is the recovery of the large volume the carbon fibre waste to provide added value materials. FOREST will implement efficient methods to recover 100% of CF waste to develop high-quality semi-finished materials (non-woven, organosheet/SMC, LFT) for valuable transport applications. Reshape: The use of biobased and recycled materials is a real opportunity for mobility decarbonization but a detriment on the stability and safety properties of the performance could occur. FOREST will research the influence of the multifunctional properties on the biocomposite (mechanical, fire-retardant, and EMI-shielding). The