RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Factory Automation Edge Computing Operating System Reference Implementation'.

assistant: **Concept**

Despite the proclaimed benefits (i.e. scalability, reliability, cost-effectiveness) of Future Internet (FI) technologies (i.e. edge & cloud computing, IoT/CPS) for factory automation, their adoption from manufacturers remains low for various reasons, including technology issues (e.g., poor situation awareness, limited deployments, no standards-based reference implementations) and the lack of a smooth migration path from legacy systems.FAR-EDGE is a joint effort of leading experts in manufacturing, industrial automation and FI technologies towards the smooth and wider adoption of virtualized factory automation solutions based on FI technologies. It will research a novel factory automation platform based on edge computing architectures and IoT/CPS technologies.  FAR-EDGE will provide a reference implementation of emerging standards-based solutions for industrial automation (RAMI 4.0, Industrial Internet Consortium reference architecture), along with simulation services for validating automation architectures and production scheduling scenarios. FAR-EDGE will lower the barriers for manufacturers to move towards Industrie 4.0, as a means of facilitating mass-customization and reshoring. Emphasis will be paid in the study of migration options from legacy centralized architectures, to emerging FAR-EDGE based ones.FAR-EDGE will be validated in real-life plants (VOLVO, WHIRLPOOL) in the scope of user-driven scenarios (business-cases) for mass-customization and reshoring, where tangible improvements relating to reliability, productivity increase, quality cost, reduction in adaptation effort/costs will be measured and evaluated. Also, a wide range of migration scenarios will be evaluated in the scope of a CPS manufacturing testbed.FAR-EDGE will also establish a unique ecosystem f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Can histone code-like switches govern the multifunctionality of RNA-binding proteins?' (MARS).

assistant: **Concept**

Post-transcriptional control of human gene expression is conferred by >1000 mRNA-binding proteins (RNA-BPs), which determine the utilisation and fate of mRNAs, with the aetiology of a wide-range of disorders (e.g. neurological, inflammatory, and neoplastic) being due to their dysregulation. Multifunctionality is a feature of RNA-BPs and understanding how this is coordinated and regulated is pivotal to delineating the molecular circuitry of post-transcriptional gene regulatory networks, to understand why they go wrong and how they may be manipulated. Poly(A)-binding proteins (PABPs) are central multifunctional regulators of mRNA fate, controlling multiple aspects of mRNA translation, stability and quality via interacting with functionally diverse protein partners. Consequently, their deficiency impacts physiological processes such as gametogenesis, metabolism and learning/memory, although mechanistic bases of these phenotypes are unclear, highlighting the importance of understanding their functions and regulation.A key gap in our knowledge is how PABP protein interactions, and therefore functions, are coordinated since many of its partners bind the same “PABC domain” site, through a shared “PAM2” motif. However, our recent findings lead to a novel hypothesis, which I will address, namely that the post-translational modification (PTM) status (acetylation or dimethylation) of a functionally important PABC residue, K606, determines PAM2-partner binding specificity and PABP multifunctionality. Uncovering that “histone-code like” acetylation-methylation switches operate in RNA-BPs, to coordinate their functions and achieve post-transcriptional regulation of mRNA networks, would represent a step-change in the state-of-the-art. This is especially timely since acetylations/methy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Twisting light and spin by chiral perovskites'.

assistant: **Concept**

Chirality, a fundamental property in chemistry and physics, plays a pivotal role in determining drug efficacy, advancing biomolecular analysis, and guiding the development of chiral optoelectronic devices. This concept becomes even more intriguing when integrated with halide perovskites, which are renowned for their exceptional optoelectronic properties. This integration gives rise to emergent phenomena such as chiral optical activity and chiral induced spin selectivity. These phenomena provide novel methods for manipulating light and electron spin, enabling advancements in quantum computing and innovative optoelectronic devices, including highly sensitive detectors and energy-efficient light-emitting diodes. However, fully harnessing this potential entails overcoming significant challenges in deciphering the complex quantum interactions underlying these phenomena. This necessitates a profound understanding of the interplay between light, charge, spin, and lattice vibrations within chiral perovskites.Addressing this challenge, the project pioneers an innovative computational framework that seamlessly integrates electronic structure theory, statistical physics, and molecular simulations. This multidisciplinary approach ensures computational efficiency while maintaining flexibility to incorporate additional theories and models. It provides access to gaining profound insights into the intricate physico-chemical mechanisms, as well as diverse structures and compositions to establish a robust structure-property relationship. Through this framework, this project aims to design unique chiral perovskites, which are expected to enhance the sensitivity of photodetectors and increase the energy efficiency of spin LEDs. Moreover, the fundamental insights from studying these materia
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Secure and Assured hardware: Facilitating ESTonia’s digital society' (SAFEST) under Horizon 2020.

assistant: **Objectives**

The overall aim of SAFEST is to enhance the scientific and technological capacity of Tallinn University of Technology (TalTech) in the field of Hardware Security, to be achieved through networking activities with its  internationally-leading Twinning partners: Centre National de la Recherche Scientifique (CNRS), Technische Universität München (TUM), Katholieke Universiteit Leuven (KU Leuven), and Technische Universität Graz (TU Graz). To achieve its overall aim, the 3 year project will build upon the existing strong competences of TalTech in closely-related fields, to be complemented by the specific know-how of the Twinning partners. TalTech will also make use of best practices learned from its previous Twinning experience as an enabler to the success of this project.To boost their scientific excellence and innovation capacity, the partners will implement a networking strategy focused on four complementary subtopics:- Test for security (CNRS)- Reverse engineering and defences (TUM)- Side channel attacks (KU Leuven)- Hardware-software architectural vulnerabilities (TU Graz)The networking strategy takes into account the SWOT analysis of TalTech and has the following objectives:Objective 1: Strengthen the research capability of TalTech and its Twinning partners in the area of Hardware SecurityObjective 2: Promote TalTech's competitiveness through sustainable participation in collaborative research effortsObjective 3: Raise the research profile of TalTech and the Twinning partnersObjective 4: Contribute to the safety aspects of e-EstoniaIn order to realize these objectives, the partners will implement a comprehensive set of measures via the following work packages (WPs):- Short term staff exchanges (WP1)- Short term exchanges of early stage researchers (WP2)- Organization o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Remote Sensing Science Center for Cultural Heritage' in the context of a Horizon 2020 call.

assistant: **Objectives**

The “ATHENA” proposal aims to establish a Center of Excellence in the field of Remote Sensing for Cultural Heritage in the areas of  Archaeology and Cultural Heritage through the development of an enhanced knowledge base and innovative methods.  This center will be established by twinning the existing Remote Sensing and Geo-environment Research Laboratory at the Cyprus University of Technology (CUT) with internationally-leading counterparts from other Member States of the EU, such as the  Institute of Archaeological and Architectural Heritage of the National Research Council of Italy (IBAM- CNR) and the German Aerospace Centre (DLR). The goals of the Center will be aligned with the Smart Specialization Strategy of Cyprus. The close collaboration between CUT and other experts in the field of Remote Sensing for Cultural Heritage in the EU  will form a synergic network that will permit the transfer of knowledge and training of the existing personnel of CUT. As a result, the ATHENA project will have both direct and indirect social, scientific, and economic outcomes. In addition, the implementation of the project will facilitate future collaborations with experts of the Archaeology and Cultural Heritage sector in an EU level, increase the Centers’ research capabilities, as well as enhance the research and academic profile of all participants. It is noteworthy to underline the importance of the geographical position of the Center in the region of eastern Mediterranean, a region inhabited thousands of years before and therefore abound in archaeological residues.


**Keywords:** remote sensing archaeology,  cultural heritage preservation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'SATELLITE-BASED ADS-B FOR LOWER SEPARATION-MINIMA APPLICATION (SALSA)' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

SALSA is an exploratory research project relating to multi-source ADS-B system.A multi-source ADS-B system that combines the benefit of all possible type of relays (space, maritime, air or ground based) of ADS-B messages could provide a global surveillance system to overcome the prevailing continuous surveillance constraints in the non-radar airspace (NRA).  By bringing Space based ADS-B with other sources of surveillance based on ground, air and oceanic relays, a system of system architecture is conceived; upon its benefits, new separation standards are validated through analysis using theoretical modelling for separation standard and airspace capacity, in the context of NRA.   Reduction in separation minimum and in the number of standards will bring significant benefits to ATC/ATM operations with improved aircraft surveillance and airspace management.   These two aspects, namely, a  system-of-system concept for multi-source ADS-B architecture  and analytical modelling for enhanced separation minima and airspace capacity in the context of NRA define the scope of SALSA. The analysis will also consider different scenarios of separation minima Vs. ADS-B message update rate.The study will assess the impact of performance of such a system of systems approach in the context of separation standards; it will provide an assessment of the procedural impact and impact to flight safety due to the revised minima and the system configuration.A set of recommendations to SESAR JU and other stake-holders and industry partners will be provided in order to purse the outcome of the study towards higher technology readiness level (TRL) and eventual implementation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Towards a sustainable Open Data ECOsystem'.

assistant: **Objectives**

The central aim of the ODECO consortium network is to train the next generation of creative and innovative early-stage open data researchers, to unlock their creative and innovative potential to address current and future challenges in the creation of user driven, circular and inclusive open data ecosystems. Current developments in the field of open data are characterised as highly fragmented. Open data ecosystems are often developed in different domains in isolation of each other and with little involvement of potential users, resulting in approaches that significantly limit open data reusability for users. This reduces innovation and the ability to create new valued added goods and services. Isolated domains also undermine interoperability for users acting as a barrier to data sharing. Efforts are also uncoordinated in open data training and research, where multidisciplinary approaches are scant. Bringing together different sectors (research, private sector, government, non-profit) and different perspectives (public administration, law, business, engineering), ODECO aims to address the central challenge of realizing a user driven, circular and inclusive open data ecosystem. Through its novel research and training programme, ODECO will provide early stage researchers with relevant open data knowledge, skills and research experiences that cut across disciplines, domains and sectors. ODECO will pay particular attention to the role and involvement of the multiple user groups in the open data ecosystem, within its research programme and through its public engagement activities. The involvement of  sixteen specialist partner organizations in the consortium, in addition to the expert non-academic beneficiary and academic beneficiaries, will help researchers better understand
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Quantum Optomechanics using Monolithic Micro-Resonators' (QUOM), addressing dissemination and exploitation.

assistant: **Impact**

Research groups working on mechanical systems ranging in size from nanometer-scale oscillators or centimeter-scale optical cavities to kilometer-scale gravity wave detectors are all independently approaching a regime, where the observation of quantum mechanical phenomena with mechanical objects might become observable. These results have been catalyzed by the recent development of a novel laser cooling technique which allows cooling mechanical oscillators coupled to an optical resonator.  As a result researchers from backgrounds as diverse as astrophysical gravity waves, mesoscopic condensed matter physics, and quantum optics are converging on a common set of goals related to quantum effects in mechanical systems. These goals relate to the observation of a distinct set of phenoma, such as quantum-backaction, ground state cooling, entanglement and generation of non-classical states of motion which would hallmark the birth of a new research field, “quantum optomechanics”.  Within this scientific setting, the applicant will join the research group of Dr. T.J. Kippenberg within the Division of Laser Spectroscopy of T.W. Haensch and seek to demonstrate quantum phenomena of mechanical objects in the form of toroidal monolithic microcavities. Within the tenure of the applicant it is expected to observe quantum mechanical phenomena relating to macroscopic mechanical objects. The training aspects of the project involve a significant enlargement of the scientific field of the applicant into a fast-advancing moving new area of opto-mechanics of micro-resonators, acquisition of cutting-edge micro-fabrication technical skills and the development of project management and apprentice guidance methods, essential for an independent research career. The hosting institution is the Max Pla
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Healthy Municipal Soils' in the context of a Horizon Europe call.

assistant: **Objectives**

The EU Mission ‘A Soil Deal for Europe’ (Soil Mission) aims to lead the transition to healthy soils via sustainable soil management. This requires knowledge and awareness of the importance and value of soil health and its challenges and drivers across Europe. Engaging and activating municipalities and regions across Europe to protect and restore soil health is vital for a successful Soil Mission deployment. The creation of spaces for dialogue with Quadruple Helix stakeholders, including marginalized and/or vulnerable strata of the population, on soil health and land management issues may contribute to develop a shared understanding of the challenges and help co-create solutions for the protection and restoration of soil. Within this context, HuMUS main aim is to facilitate the deployment of the Soil Mission across regions and municipalities, through: (i) the creation and experimentation of spaces for social dialogue on soil health among public and private actors in Europe; (ii) the promotion of a shared understanding and co-assessment exercises of soil challenges (biophysical and socio-economic dimensions); and, (iii) the enhancement of knowledge sharing among municipalities and regions, including on the needed transformations in current S4 (Sustainable Smart Specialisation) strategies and the use of available EU funds to support the transition.HuMUS will support the involvement of stakeholders and citizens in the decision-making processes via case studies, educational and capacity building activities as well as exchanges of best practices at regional and local levels. HuMUS will further contribute to raising the problem awareness of regional and local governments, businesses and society at large through the use of the Bio-districts multi-stakeholder methodology, whereb
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Extra-gonadal roles of Anti-Müllerian Hormone in the aetiology of polycystic ovary syndrome: the domino effect to reproductive neuroendocrine dysfunctions' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Reproduction in mammals is dependent on specific neurons secreting the Gonadotropin Hormone-Releasing Hormone (GnRH). Many reproductive disorders in humans are associated with abnormal or deficient GnRH secretion. Among reproductive dysfunctions, polycystic ovary syndrome (PCOS) is the most common form of female infertility with a prevalence of up to 10%, characterized by increased ovarian androgen biosynthesis, oligo-anovulation and frequent metabolic morbidities. Because women with PCOS have increased luteinizing hormone (LH) pulse frequency, it has been inferred that the pulse frequency of GnRH must be accelerated as well. However, so far PCOS has been considered mainly as a gonadal pathology and possible regulations from the central nervous system or interactions with it remain elusive. In patients with PCOS, ovarian levels of Anti-Mullerian Hormone (AMH) are also elevated, indicating the potential relevance of AMH for PCOS diagnosis and management. Recently, we showed that AMH acts directly on GnRH neurons to increase neuropeptide secretion, raising the intriguing hypothesis that AMH-dependent regulation of GnRH release could be involved in the neuroendocrine control of fertility and pathophysiology of PCOS. By providing integrative, functional and mechanistic in vivo strategies, combined with clinical human investigations, REPRODAMH will represent a major step forward into the understanding of PCOS with the final goal of developing new therapeutic strategies. To achieve these goals we will:1: Determine whether developmental or postnatal AMH excess leads to PCOS endocrine disturbances by hyperactivation of GnRH neurons.2: Study whether inhibition of GnRH neuronal activity rescues the neuroendocrine reproductive phenotype in PCOS-mouse models.3: Study whether modifi