RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Structural studies of the interaction between Hsp70 and alpha-synuclein'.

assistant: **Objectives**

Protein misfolding and aggregation are associated with a wide range of severe, and so far incurable, neurological and systemic disorders, which include Alzheimer's and Parkinson's diseases, and type II diabetes. As these conditions are the consequence of the impairment of protein homeostasis, a variety of cellular natural defenses have evolved to eliminate protein aggregates as they form. In this application we are concerned with the problem of understanding the molecular basis of such defense mechanisms, by focusing on the specific case of the interaction between alpha-synuclein, a protein closely involved in Parkinson's disease, and Hsp70, a molecular chaperone with a variety of cellular functions, including the ability of recognising misfolded or aggregated proteins. We are going to address this problem using a wide arsenal of biophysical, biochemical and computational methods, including FRET and NMR spectroscopy, fluorescence methods, dynamic light scattering, transmission electron microscopy, isothermal titration calorimetry and molecular dynamics simulations. The outcome of this study will provide relevant  structural information at atomic level on the binding modes of Hsp70 with diverse molecular forms of alpha-synuclein related to neurotoxicity. The results of this project are expected to increase our understanding of the molecular basis of the interactions between molecular chaperones and unstructured states of proteins, as well as to provide insights for the development of novel  strategies for the rational design of therapeutic approaches against protein aggregation.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Hydrogen fuel cell trucks for heavy-duty, zero emission logistics'.

assistant: **Objectives**

H2Haul will develop and demonstrate a total of 16 new heavy-duty (26–44t) hydrogen fuel cell trucks in real-world commercial operations. The project includes two major European truck manufacturers (IVECO and VDL), who will build on existing small-scale prototyping activities to develop new zero-emission trucks tailored to the needs of European customers, mainly in large supermarket fleets. The vehicles will be standardised as far as possible to help encourage the development of the European supply chain. New high-capacity hydrogen refuelling stations will be installed to provide reliable, low carbon hydrogen supplies to the trucks. Most of the stations will be publicly accessible and this project will thus support the uptake of a broader range of hydrogen-fuelled vehicles.The vehicles and infrastructure will be thoroughly tested via an extended trial with the high-profile end users over several years. The comprehensive data monitoring and analysis tasks will ensure that the technical, economic, and environmental performance of the hardware is assessed, and that the business case for further deployment of heavy-duty fuel cell trucks is developed. The scope and ambition of this innovative project will create a range of valuable information that will be disseminated widely amongst truck operators, representatives of the retail sector, policy makers, and the broader hydrogen industry. Hence, H2Haul will validate the ability of hydrogen fuel cell trucks to provide zero-emission mobility in heavy-duty applications and lay the foundations for commercialisation of this sector in Europe during the 2020s.


**Keywords:** Hydrogen, fuel cell, heavy duty transport, zero emission
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Demonstration of ATM Improvements Generated by Initial Trajectory Sharing - Airspace User Part' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

*  DIGITS-AU is the essential Airspace User complement to the DIGITS project (Demonstration of ATM Improvements Generated by Initial Trajectory Sharing). DIGITS was granted under H2020-SESAR-2015-2, SESAR.ID-VLD.Wave1-27-2015, and its continuation is dependent on the participation of Airspace Users (AU).*  As required, DIGITS-AU brings together Airspace Users- who operate (even partially) in the airspace of ANSPs participating to DIGITS, namely DFS, ENAV, MUAC and NATS and - who will receive through this Call new onboard avionics capability which allows to downlink trajectory predictions, the so-called Extended Projected Profile (EPP), for sharing with Air Traffic Control.*  This proposal addresses also the interface with other SESAR 2020 projects, by nature with PJ31 DIGITS, but also with PJs 01, 09, 10 and 18 in order to contribute to the identification of benefit potentials facilitated by this new airborne technology. The capture of real fuel burn reduction for DIGITS-AU flights is not possible due to the fact that ground ATC systems are used in an pre-operational or shadow mode, based on which air traffic controllers may not alter their instructions. Nevertheless ""what-if"" cases shall be identified as far as observations possibly allow and the theoretical fuel burn gain calculated.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Advanced European Network of E-infrastructures for Astronomy with the SKA'.

assistant: **Concept**

The objective of the AENEAS project is to develop a concept and design for a distributed, federated European Science Data Centre (ESDC) to support the astronomical community in achieving the scientific goals of the Square Kilometre Array (SKA). The scientific potential of the SKA radio telescope is unprecedented and represents one of the highest priorities for the international scientific community. By the same token, the large scale, rate, and complexity of data the SKA will generate, present challenges in data management, computing, and networking that are similarly world-leading. SKA Regional Centres (SRC) like the ESDC will be a vital resource to enable the community to take advantage of the scientific potential of the SKA. Within the tiered SKA operational model, the SRCs will provide essential functionality which is not currently provisioned within the directly operated SKA facilities. AENEAS brings together all the European member states currently part of the SKA project as well as potential future EU SKA national partners, the SKA Organisation itself, and a larger group of international partners including the two host countries Australia and South Africa.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'The Cosmic Soul: Renaissance Humanism and Natural Philosophy'.

assistant: **Concept**

I am proposing to spend two years at the Center for the History of Philosophy and Science (CHPS) at the Faculty of Philosophy of Radboud University Nijmegen (the Netherlands). There, I propose to carry out a large research project and at the same time to acquire a number of new skills in the domains of teaching, editorship, organization and research methodology. I have good reasons for believing that my planned publications, together with my expanded curriculum, will allow me to compete successfully for a university position in Europe at the end of my fellowship. My research project, which will culminate in my third book-length monograph, aims to investigate the impact of Renaissance humanism on the development of natural philosophy (a traditional discipline that included physics, biology, astronomy, etc.) in the sixteenth and seventeenth centuries. In particular, I shall investigate Renaissance and early modern ideas concerning the provenance of life and their link to notions of universal animation, of the ‘world soul’, and of celestial as well as divine causation. Although the history of this ‘cosmic dimension of the soul’ is not only a fascinating subject, but also very central to our understanding of early modern thought, it has been strangely neglected in the available scholarship. My proposed research topic requires an interdisciplinary approach, as it involves the histories of philosophy, of science, of theology and of medicine. The CHPS at Nijmegen is, in Europe, probably the best place for such a project, because of the presence of eminent historians of both philosophy and science in its staff. My proposed sojourn at the CHPS will combine the research just sketched with the acquisition of skills that are strictly related to my research.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Innovative outdoor solar and kinetic energy harvesting pavement system' under Horizon 2020.

assistant: **Concept**

PLATIO outdoor solar and kinetic energy harvesting pavement system is developed by our start-up company, InnovatívTérburkolatfejlesztő Kft. We are an enthusiastic team of professionals with engineering and sales/marketing background.With our flagship project PLATIO, an unconventional primarily outdoor energy producing paving system our mission is tooffer a viable solution to harvest and exploit renewable energy in urban environments.Our project gained serious awareness and managed to involve venture capital from angel investors to create the prototypesof our pavement system. We are also a mentored project within Design Terminal, a leading technological and startup mentorprogram in Hungary.PLATIO is an unconventional, a primarily outdoor energy producing paving system and an alternate to usual pavements.Contrary to most of the applied pavements nowadays, PLATIO does not take material (such as stone, gravel, cement andwood) and energy from nature to build human environment, but uses the normally appearing garbage and energy.Consequently PLATIO is a paving platform made of recycled plastic. The planned product integrates different types ofenvironmental friendly technologies such as solar panels to use the solar power and kinetic energy converters to transformthe energy of human steps or any other means of vibration. The units are compact and modularly connect together makingelectronic contact without additional wiring by a powerline communication system which connects automatically during theestablishment.Combining recycled plastic, solar panels and piezoelectric kinetic energy converters we created the PLATIO technology thatcan be used for several scenarios from household (B2C) to B2B solutions, such as smart advertisement providers. Insteadof trying to create the cheapes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'NEXT GENERATION IMAGING FOR REAL-TIME DOSE VERIFICATION ENABLING ADAPTIVE PROTON THERAPY' to be submitted under Horizon Europe.

assistant: **Abstract**

The NOVO project will address a fundamental issue in proton radiotherapy (PT) of cancer, namely the lack of real-time dose verification (RDV) that significantly limits the potential of PT due to uncertainties in the precise delivery of the prescribed dose. In the NOVO project, we will develop the first proof-of-concept of an RDV technology adaptable to any PT treatment and bring the concept to TRL 4 by also considering integration into the PT clinical workflow. The RDV technology will be pivotal for enabling the next generation of adaptive PT therapy, i.e., dose-guided real-time adaptive therapy. Real-time measurement of the dose to targeted and non-targeted tissues will be the key to truly empower patient-centered, personalized cancer treatment, important to improve curation and quality-of-life post-treatment. As a high-risk/high-gain project, NOVO aims at a first-of-its-kind RDV technology through the unique synergy between (1) cutting-edge, inexpensive organic scintillator technology that can detect secondary radiation during treatment for non-invasive measurements, (2) novel and fast image reconstruction, artificial intelligence (AI)-accelerated models and AI-enhanced image reconstruction to allow simultaneous detection of multiple radiation species and tissue compositional analysis, (3) tumor-tracking and imaging of tissue radio-sensitivity based on oxygen levels, (4) intelligent automation of decision-making schemes for real-time dose-guided adaptive therapy. The project will essentially open a new era in PT that enables curing more cancer patients and reducing toxicity from treatment. The NOVO consortium covers the entire value chain of RDV development (technology providers, theory and modelling, technology integration and PT clinics) and optimally engages nuclea
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Antibiofouling Nanopatterned Electrospun Membranes for Nanofiltration Applications' (ANEMONE).

assistant: **Innovation**

Water-stress in an increasing global problem and solutions such as water recycling and seawater desalination are nowbecoming a necessary part of the water infrastructure. The technology for the production of safe drinking is increasinglydependent on these more diverse sources and a key enabling technology is membrane filtration. While membrane systemare effective, the operating costs of such systems are hampered by fouling which increases the energy requirement forprocess operation. The unique idea of this Proof of Concept is to develop an electrospun nanostructured membrane whichcan be integrated into water filtration technologies. The unique method of fabrication will produce an inherently antibacterialand antibiofouling surface in a one-step process, cutting the number of manufacturing steps. This concept, when deployedcommercially is expected to dramatically reduce the operating costs of membrane processes for water treatment. Thecommercialisation route of the product will be through the patent protection and the licensing of the technology with a viewto rapid commercialisation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Proteus and object-oriented frameworks applied to network data acquisition evolutionary solutions' (PROFANES).

assistant: **Concept**

Requirements in the telecommunications software sector change extremely rapidly due to the introduction of new technologies and increasing competition resulting from de-regulation. Interoperability of new applications with legacy systems is also an imperative in a market where companies still operate a vast amount of Operation Support Systems (OSS) that were developed several decades ago. Software reuse has been recognised as a strategic imperative for these companies. In particular, the production of software in a domain engineering context is most appropriate to foster software reuse at company-level, and thus reduce time-to-market, increase software quality, facilitate inter-operability of applications, and capture domain knowledge. PROFANES aims to reach the following 3 objectives:- Demonstrate that Domain Analysis techniques derived from the PROTEUS method are adequate to capture the knowledge about an evolutionary domain.- Demonstrate that Object-Oriented Frameworks design techniques are adequate and efficient to capture in a stable model the generic features of a domain component.- Demonstrate that Domain Analysis techniques combined with Object-Oriented Frameworks together enable software reuse within a domain, by allowing multiple instantiations of a domain component, thus reducing overall time-to-market, reducing costs, and increasing software quality.THE EXPERIMENTThe starting point for PROFANES will be the Domain Analysis methodology proposed in the PROTEUS ESPRIT project #6086. This method will be extended and adapted to fit into Sodalia's engineering environment. The resulting Domain Analysis methodology will be applied experimentally to define a Domain Model for a family of network data collection applications. Following this activity, an Object-Oriented
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Quantifying the relative importance of natural and anthropogenic drivers of spatial variation in vulnerability to predict species extinction risk' in the context of a Horizon 2020 call.

assistant: **Objectives**

The world is losing biodiversity at an unprecedented rate, altering the functioning of Earth’s ecosystems and their ability to provide society with the services needed to prosper. To prevent biodiversity loss it is critical to understanding species extinction patterns. Studies linking species extinction risk with biological traits provide good insights but models show small predictive power generating uncertainty about how to translate knowledge into conservation strategies. Since global species extinction is the result of a sequence of local population extirpations, it becomes more meaningful understanding vulnerability at population level. This implies knowing the drivers of population extirpations within the species geographical context. This spatial context is determined by ecological and evolutionary factors that imprint to local populations a natural ability to tolerate anthropogenic threats. Focusing on terrestrial mammals, DRIVE aims to quantify the relative importance of natural and anthropogenic factors in driving local populations to collapse. For this, DRIVE proposes to build a novel hierarchical biogeographic template to incorporate the species environmental context into ecological models. The ultimate goal is to include the species inherent vulnerability as a key intrinsic trait into models predicting species extinction risk. DRIVE objectives will be accomplished by using innovative methods and novel theoretical advances in ecology, working in a multidisciplinary context involving biogeography, population modelling, and applied conservation. DRIVE is a collaborative project between EBD-CSIC (Spain, beneficiary) and the Department of Zoology-Oxford University (UK, partner), which outcomes will contribute to the consolidation of the European Area on biodiver
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Scaling up the WHO-PEN package for diabetes and hypertension in Swaziland: a nation-wide cluster-randomised evaluation of three strategies in Swaziland (WHO-PEN@Scale)'.

assistant: **Objectives**

Swaziland has a very high prevalence of both diabetes and hypertension, with the majority of those affected being undiagnosed. Like many other countries in sub-Saharan Africa (SSA), however, Swaziland provides care for diabetes and hypertension only through physician-led teams in hospitals. The country has recently conducted a successful feasibility pilot of the World Health Organisation’s Package of Essential NCD Interventions for Primary Health Care in low-resource settings (WHO-PEN). The WHO-PEN@Scale project aims to improve diabetes and hypertension control at the population-level by helping Swaziland identify and scale up the most effective healthcare delivery model for WHO-PEN implementation at scale. Specifically, we will conduct an innovative nation-wide two-phased adaptive randomised study to i) rigorously assess the effectiveness and cost-effectiveness of four novel community-based healthcare delivery models to scale up WHO-PEN for diabetes and hypertension nationally, ii) study in-depth the real-life implementation of the WHO-PEN national scale-up in Swaziland to generate lessons for other countries, and iii) actively disseminate the Swazi experience along with an open-source toolkit for WHO-PEN scale-up to policy makers in SSA. WHO-PEN@Scale will therefore provide a blueprint of primary health system strengthening for diabetes and hypertension – and ultimately non-communicable diseases (NCDs) more generally - for other countries in the region. WHO-PEN@Scale is highly relevant to this work programme because i) the interventions contained in WHO-PEN have been shown to be cost-effective, ii) the scale-up is government-led, and iii) we assess the impact of WHO-PEN@Scale on diabetes and hypertension control at the population-level.


**Keywords:** Adaptive Random