RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'small Scale interlocking mechanisms for Strong and Tough mEtamatEriaL' (SSTEEL).

assistant: **Concept**

Brittleness limits the design and lifetime of some polymeric, metallic, and almost all ceramic materials in both structural and functional engineering applications, from the design of plane engine turbine blades to the newest solid-state electrolyte in batteries. This brittleness is intrinsically present in material composition that cannot plastically deform and make them sensitive to any defect introduced during their fabrication or usage. The goal of this project is to produce small Scale interlocking mechanism for Strong and Tough mEtamatEriaL (SSTEEL) that will provide a material independent solution to brittleness. Interlocking mechanisms provide in theory one of the most efficient way to increase toughness by creating crack blocking compressive stresses in response to tensile stresses. Because a brittle material strength is inversely linked to its size, my team and I first objective will be to develop a new process to form interlocking mechanism based on micron-sized elements using a combination of light-based additive manufacturing, shrinking ink design to access sub-printer resolution, and fragmentation. The second objective will be to implement this mechanism at an even smaller scale using rational material selection, solid state chemistry, and colloidal processing to fabricate an interfacial binder for the elements. The fracture process of SSTEEL sample will span several length scales and a specific task will be to use a combination of image correlation and modelling to fully characterise the existing damaging mechanism and inform the improvement of future designs.These new structures and concepts developed by my group will promote the development of tough structure for today’s and future structural and functional engineering applications by changing any britt
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Terrestrial energy recovery using advanced stirling heat-pumps for residential temperature management', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

Around 80% of the total domestic energy demand in Europe is used of heating and cooling, amounting to 2,600 TWh p.a, with the majority of heating provided by gas (50%). There are very few efficiency improvements to be made using conventional heaters and boilers, as most are already over 90% efficient. Therefore, alternative heating systems such as ground source heat pumps are seen as the future for heating.Heat pumps are already used in some European countries but have a number of inherent drawbacks that limit their popularity:- Existing ground source heat pumps are electrically driven, meaning retrofits to gas-based systems are harder- Electric heat pumps optimally deliver water at 50°C, which is too low for most European wet central heating systems- Ground loop heat exchangers are either very expensive (vertical bore) or very disruptive and large (horizontal trench), meaning many homes either cannot or do not wish to install them.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Model Based Improvement of Performance, Maintainability and Reliabi lity of Helicopter Structures'.

assistant: **Innovation**

Foreseen ResultsA set of procedures and refined techniques for the optimal execution ofground and flight tests of helicopter for vibration purposesthe corresponding data analysisthe generation of the finite element modelthe correlation and updating of the various data setsA guideline to use the obtained data to the improvement of performance, reliability and maintainability of the helicopter.The demonstration of the investigated approach for a few selected design problems.The main aim of the project is to realize a consistent approach to the model supported design of complex structures. The methodology will be developed and validated around the industrial case of a helicopter structure, but its applicability will be general. This virtual prototyping" approach should form the basis for model simulation as well as design of proper modifications of the structure, improving performance and reliability and safety. Ultimately, it should enable the development of a model-based predictive maintainability strategy.The main activities of the project will focus on the modelling of complex structures in real operating conditions, particularly on improving the numerical CAE (FEM) model based on ground and flight test data modelling.This will start from a comprehensive evaluation of the state-of-the-art in this field involving the selection and validation of the most appropriate techniques, the transfer of the required know-how on modelling and model improvement to the Polish partners, and the joint execution of the testing and numerical modelling work.The result of the project will be a documented procedure for the application of model based virtual prototyping of complex structures, validated for the case of helicopter design. It will include the required refined methodologies for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'MULTI-OBJECTIVE DESIGN SPACE EXPLORATION OF MULTI-PROCESSOR SOC ARCHITECTURES FOR EMBEDDED MULTIMEDIA APPLICATIONS' (MULTICUBE).

assistant: **Innovation**

Many point tools exist to optimize particular aspects of embedded systems. However, an overall design space exploration framework is needed to combine all the decisions into a global search space, and a common interface to the optimization and evaluation tools. The MULTICUBE project focuses on the definition of an automatic multi-objective Design Space Exploration (DSE) framework to be used to tune the System-on-Chip architecture for the target application evaluating a set of metrics (e.g. energy, latency, throughput, bandwidth, QoR, etc.) for the next generation embedded multimedia platforms. To support both the static and the run-time design exploration flow, the MULTICUBE project will develop a multi-level system specification and modeling framework to provide static and dynamic evaluation of the system-level metrics. The design methodology will be implemented at system-level in a set of open-source and proprietary EDA tools to guarantee a large exploitation of the results of the MULTICUBE project in the embedded system design community. The overall goal is to support the competitiveness of European industries by optimizing embedded hardware/software systems while reducing the design time and costs.<br/>The MULTICUBE project is strongly industry-driven: two European industrial partners (STM-Italy and DS2) and STM-China will define the requirements of the design tools and validate step-by-step the results of the exploration tools to design a set of target industrial applications. The integration of design tools and the commercial exploitation of the tools will be done by an European SME, ESTECO. ALARI will be mainly in charge of the dissemination and exploitation activities. The research and technological development will mainly be done by IMEC, Politecnico di Milano,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Bacteriophages, phage-host interactions and evolution of defence mechanisms in beneficial bacterium Propionibacterium freudenreichii'.

assistant: **Objectives**

Bacteriophages (phages) infecting Propionibacterium freudenreichii, a bacterium known for production of active vitamin B12 and for causing well-documented benefits to human health, are more diverse than those identified for closely related genera. At the same time, the defence mechanisms protecting the bacterial strains (hosts) from phage attacks are more diverse as well. These two phenomena suggest that P. freudenreichii strains and their phages have experienced complex interactions in phage-bacterium arms race. However, both phages attacking, and the defence mechanisms that this important food-grade Actinobacterium uses to protect itself from phage attacks are currently severely understudied. In CO-DEfENDENCE, I will use an innovative approach of systematic study of the defence mechanisms not only from the perspective of the bacterium, but also from the perspective of the phage. The use of strains and phages isolated from samples of different origin will ensure diversity of material subjected to analyses by a combination of phenotypic, genomic, proteomic and imaging methods. This multidisciplinary approach is possible due to guidance offered by world-class phage specialists at one of the world’s top universities, the University of Copenhagen. The expected result of CO-DEfENDENCE is elucidation of complex interactions between P. freudenreichii and its phages, which led to the high diversity of the phages and the multitude of defence mechanisms employed by the strains.  As an added benefit, these results have a great potential for being translated into novel genetic tools and to aid the development of phage therapies, especially those aimed at pathogenic Actinobacteria.


**Keywords:** Bacteriophage,  Propionibacterium,  page-host interactions,  probiotics
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Protein pathway analysis in growth factor signaling networks' (1998-2002).

assistant: **Innovation**

A systematic approach to identify novel targets in signalling of vascular endothelial growth factor receptors is provided, combining single-step enrichment of tyrosine substrates, ultra-sensitive mass spectrometry and cell -based assays for target systematic approach to identify novel targets in signalling of vascular endothelial growth factor receptors is provided, combining single-step enrichment of tyrosine substrates, ultra-sensitive mass spectrometry and cell -based assays for target
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Real-time reconstruction of epidemic dynamics from viral phylogenies using Deep Learning' (2021-2027), addressing dissemination and exploitation.

assistant: **Impact**

Reconstructing epidemic dynamics in real-time has become crucial for effective disease management, as demonstrated by the COVID-19 pandemic. Traditional methods rely on epidemiological data (e.g., reported cases), which can be biased or incomplete due to variable testing policies, particularly in resource-limited settings. Instead, phylodynamics has emerged as a valuable toolkit for using viral phylogenies to understand epidemic dynamics. However, conventional phylodynamic methods rely on mathematical formulas and approximations, which are not scalable to large datasets and are time-consuming, limiting their use primarily to retrospective rather than real-time analysis.This proposal aims to transform phylodynamics by integrating it with deep learning to bypass the cumbersome likelihood calculations, thereby facilitating real-time analysis directly from sequence data. I will develop innovative deep learning models to explore the relationships between phylogenetic trees and epidemiological parameters of viruses with epidemic potential, such as SARS-CoV-2, influenza, RSV, and mpox. These models are designed to rapidly and accurately estimate time-varying epidemiological metrics, including transmission heterogeneity, basic reproduction numbers, infectious and incubation periods.This initiative is set to revolutionize our ability to model and comprehend infectious diseases in real-time, elevating sequence data to a critical, standalone data source. It will incorporate cross-validation with epidemiological inference from reported cases and wastewater analyses, reducing reliance on any single data source and enhancing both public health responses and infectious disease surveillance. Furthermore, by simulating incremental data collection that reflects real outbreak conditions,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Paraplegia Prevention in Aortic Aneurysm Repair by Thoracoabdominal Staging with ‘Minimally-Invasive Segmental Artery Coil-Embolization’:  A Randomized Controlled Multicentre Trial' (PAPA-ARTIS) under Horizon 2020.

assistant: **Objectives**

Chronic aortic aneurysms are permanent and localized dilations of the aorta that remain asymptomatic for long periods of time but continue to increase in diameter before they eventually rupture. Left untreated, the patients’ prognosis is dismal, since the internal bleeding of the rupture brings about sudden death. Although successful treatment cures the disease, the risky procedures can result in paraplegia from spinal cord ischaemia or even death, particularly for aneurysms extending from the thoracic to the abdominal aorta and thus involving many segmental arteries to the spinal cord, i.e. thoracoabdominal aortic aneurysms of Crawford type II.  Although various strategies have achieved a remarkable decrease in the incidence of paraplegia, it is still no less than 10 to 20%.  However, it has been found that the deliberate occlusion of the segmental arteries to the paraspinous collateral network finally supplying the spinal cord does not increase rates of permanent paraplegia.  A therapeutic option, ‘minimally invasive segmental artery coil embolization’ has been devised which proceeds in a ‘staged’ way to occlude groups of arteries under highly controlled conditions after which time must be allowed for arteriogenesis to build a robust collateral blood supply. PAPA-ARTiS is a phase II trial to demonstrate that a staged treatment approach can reduce paraplegia and mortality dramatically. It can be expected to have both a dramatic impact on the individual patient's quality of life if saved from a wheelchair, and also upon financial systems through savings in; 1) lower costs in EU health care; 2) lower pay-outs in disability insurance (est. at 500k in Year 1), and; 3) loss of economic output from unemployment. Approx. 2500 patients a year in Europe undergo these high risk
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Tuning Emergent Phases in 2D Materials' in the context of a Horizon 2020 call.

assistant: **Objectives**

The goal of EMERGE is to create new types of two-dimensional materials of the highest quality, and exploit new types of quantum phenomena that emerge in the lower dimensional limit. By combining ultra-high purity fabrication of 2D materials with a high level of control, with high precision spectroscopy, we aim at being able to tailor the phase of these materials with atomic precision. Since the discovery of graphene, there has been an ongoing search for new Dirac materials which exhibit exotic electronic behavior in the two-dimensional limit, in which the spin and electronic degrees of freedom can be manipulated. Toward this end, the family of transition metal dichalcogenides (TMDCs) is extremely promising, as this family of materials exhibits semiconducting behavior, novel spin transport, charge ordering, and superconductivity, when simply selecting the transition metal ion and the interface. However, the role of the environment and how this determines the quantum phases of these materials is still not well understood, and moreover there are still many of these materials which have not been realized. The objective here will be to fabricate and tune TMDCs at the 2D limit, to realize new types of TMDCs, in order to realize exotic phases of matter to unravel the role of the environment and material in creating and discovering new types of quantum phases of matter in these materials. Our goals will be accomplished by combining CVD fabrication of TMDC single layers in ultra-high vacuum, with in-situ characterization of these films with cutting edge spin-polarized scanning tunneling microscopy at ultra-low temperature and high magnetic fields, and angular resolved photoemission in order to fully understand the electronic properties of our materials.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'eXtended Reality for Education', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The European EdTech sector is playing an increasingly important role in driving forward digital transformation in Europe covering all education, training sectors. According to estimates, the sector saw a 15% increase on investments in 2021 and global investments are expected to reach over $87 billion in the upcoming decade. Notwithstanding, the sector is heavily fragmented across the European Union with many small players and few companies playing a global role. The European XR industry has evolved and maintained a leading role globally in software and content production. The use of XR can expand the range of activities through which students can gain hands-on experience, enabling them to go beyond abstract knowledge and supporting skills-based teaching and learning. Currently, developing XR applications for education require specialised knowledge and strong XR development skills. The process takes a lot of effort, time, and money. XR4ED concept is to: a) bring together EdTech and XR community and resources, overcoming fragmentation issues and encouraging the acceleration of innovation for personalised, innovative, efficient, and inclusive learning using XR;b) build a one-stop-shop and open marketplace for XR applications for learning, training and education that will act as a European reference platform on learning and teaching with XR.XR4ED will focus on the following sectors which must be further developed to make Europe a leader in cutting-edge technologies for education:•Boost the deployment of innovative XR applications for learning, training, and education.•Enable digital start-ups, SMEs, and industry active in the EdTech sector to further advance early prototypes, of digital learning solutions/apps using XR to a market-ready product.•Provide a single point of ac
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Distributed 3D Object Design'.

assistant: **Concept**

The DISTRO network brings together leading laboratories in Visual Computing and 3D Computer Graphics research across Europe with the aim of training a new generation of scientists, technologists, and entrepreneurs that will move Europe into a leading role in the scientific and technological innovation in the area of casual, distributed 3d object design and customization.Whilst digital content has certainly grown, the world’s economy is still dominated by manufacturing. A new class of ""rapid prototyping"" technologies, from 3D printers to laser cutters, are making the process of manufacturing physical objects look increasingly like that of creating digital content. Just as the Web democratised digital innovation, the next ten years will see the application of these lessons to the real world. This new industrial revolution can only occur if it is as simple for real world objects to be captured, and modified as it is for music, text, and images. This is not yet the case, with most professional design software requiring a significant amount of time and investment to master. There is a real need for tools that are focused on making it simple for amateurs to create new products without experience or training – expediting the path from idea to entrepreneurship.  Our network proposes a timely and innovative research training programme for the distributed capture, editing, and fabrication of objects - from the real world to digital and back again. We want to enable users to casually capture objects, which can then be easily shared on the Web and customised in simple yet powerful ways. The research training programme will be conducted by our network, consisting of a mix of academic and private partners. Through collaborative research, secondments, and training events, we will ed