RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'SELF-UPGRADING OF OLD-DESIGN GAS TURBINES IN LAND AND MARINE INDUSTRIES' under Fourth Framework.

assistant: **Concept**

More than 10000 old (1962-1982 'peak-power') and newer (1982-1992 'combined-cycle') gas turbines can be upgraded by project proprieraty methods using only End-User's own standard machine shops. Expected benefits include increase in gas-turbine life-span and less pollution and fuel consumption.METHOD 1 destroys combustors hot spots and provides fresh oxygen to fuel droplets for less pollution.METHOD 2 can save 0,3% liquid-fuel consumption and reduce up to 90% emissions.METHOD 3 increases engine life-span to provide significant industrial saving-especially in combined cycle electricity-generation. It is based on civilising a military technology developed by co-ordinator. Designed mainly to reduce thermal stresses, creep and oxidation ('burning') rates as well as hot-spot damages to turbine stator-vanes and turbine blades, it was first introduced and dem/val by co-ordinator for post-1989 jet engines of high-performance fighter aircraft.Project aim is to provide the highest benefits by combining at least methods 1 and 3 for more rational uses of energy in gas-turbine-based electrical power generation, including the feasability to export the technology.Expected socio-economic benefits are:1.Cleaner air and less damage to environment; 2.Efficient-rational use of energy; 3.Provision of a new advanced technical data-base for furthering legislation and clean air law enforcement; 4. Economic benefits that can be based on SME's and extant end-user machine shops for self upgrading of old and some newer gas turbines in combined-cycle STAG and CHP plants; 5.Industrial benefits which can be easily disseminated across the entire EU via SME's and the self-upgrading methodology advanced by this project. More specific results are outlines below.1- GT life span increase2- Co-operation, sha
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Tools for high productivity engineering design' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

High-performance computing now allows simulation to be used as a predictive tool in the design of complex components. Such components include combustion chambers, turbo-machinery, civil engineering structures and automotive parts. The design of these involves computational fluid dynamics, computational electromagnetics, seismic analysis and computational structural and vibrational analysis. The objective of the project is to develop a highly productive interactive open environment supporting HPCN simulation techniques applied to engineering problems. The project aims at integrating in a common framework tools developed within other EU projects and elsewhere. The integrated framework will be open to all software packages. This will be achieved by making use of currently available and emerging standards in distributed computing and data. The effectiveness of the environment will be demonstrated in three complex industrial design cycles: - Design of civil aircraft components using computational electromagnetics.- Sensitivity analysis of dams under seismic loads using structural mechanics.- Development of an experimental rig using computational fluid dynamics. http://www.bertin.fr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Background cRiteria for the IDentification of Groundwater thrEsholds' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

The Commission proposal of Groundwater Directive COM(2003)550 developed under Article 17 of the Water Framework Directive (2000/60/EC) sets out criteria for the assessment of the chemical status of groundwater, which is based on  existing Community quality standards (nitrates, pesticides and biocides) and on the requirement for Member States to  identify pollutants and threshold values that are representative of groundwater bodies found as being at risk, in  accordance with the analysis of pressures and impacts carried out under the WFD.In the light of the above, the objectives  of BRIDGE are :  i) to study and gather scientific outputs which could be used to set out criteria for the assessment of the chemical status of groundwater, ii) to derive a plausible general approach, how to structure relevant criteria appropriately with the aim to set representative  groundwater threshold values scientifically sound and defined at national river basin district or groundwater body level, iii) to check the applicability and validity by means of case studies at European scale, iv) to undertake additional research studies to complete the available data,v) and to carry out an environmental impact assessment taking into account the  economic and social impacts. The project shall be carried out at European level, involving a range of stakeholders and  efficiently linking the scientific and policy-making communities.Considering the requirement of the diary of the  Groundwater Daughter Directive proposal, which implies that groundwater pollutants and related threshold values should be identified before December 2005 and listed by June 2006, the duration of the project should be 24 months. In that way  the proposed research will contribute to provide research elements that will be indisp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Bridging spatial and temporal resolution gaps in the study of cell division'.

assistant: **Concept**

Cell division underlies the growth and development of all living organisms. Following partitioning of bulk cytoplasmic contents by cleavage furrow ingression, dividing animal cells split by a distinct process termed abscission. Whereas a number of factors required for abscission have been identified in previous studies, it is not known by which mechanism they mediate fission of the intercellular bridge between the nascent sister cells. Here, we will establish correlative workflows of time-lapse imaging, super resolution fluorescence microscopy, electron tomography, and electrophysiological assays to bridge spatial and temporal resolution gaps in the study of abscission. We will further develop computational tools for image-based RNAi screening. With this, we aim to:1) elucidate how membrane and cytoskeletal dynamics coordinately split the intercellular bridge;2) uncover the signaling pathways controlling abscission timing.Failure in abscission can lead to aneuploidy and cancer. Elucidating its mechanism and temporal control is therefore of general biological and medical relevance. The computational and correlative imaging methods developed in this project will further provide the research community new possibilities for mechanistic studies in intact cells.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Assessment of tiltrotor fuselage drag reduction by wind tunnel tests and CFD'.

assistant: **Innovation**

The DREAm-TILT project is focused on the assessment of drag reduction achieved through the aerodynamic optimization of some critical components of the ERICA tiltrotor fuselage. This will be accomplished both from an experimental and a numerical point of view.A CFD-based optimization activity has been carried out in GRC2, and proper shapes of some fuselage components (i.e. wing/fuselage junction, wing/nacelle junction, nose, landing gear sponson and empennage) have been identified, that contribute to reduce aircraft drag and enhance  aerodynamic efficiency.In DREAm-TILT, the benefits obtained from the aerodynamic optimization in terms of drag reduction will be thoroughly assessed through a dedicated wind tunnel campaign: specifically, the final optimized fuselage will be tested and the drag reduction with respect to the original configuration will be determined. All the optimized components will be tested sequentially with the aim of getting an accurate drag breakdown and identifying the contribution of each component to the overall aerodynamic performance of the fuselage. Additional classical flow visualization runs and infrared thermography will be finally carried out to enhance knowledge on the transition and separation regions for the different drag reduction configurations.Moreover, a CFD activity will be carried out on both the model scaled and the full scale aircraft in order to evaluate rotor effects and the full scale (Mach dependent) characteristics. In a first phase, a series of blind test simulations at wind tunnel conditions will be performed for both basic and optimized configurations. In a second stage, the numerical results on both the baseline and optimized ERICA geometries will be compared with the acquired wind tunnel data. Finally, the numerical model
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Personalised Medicine by using an Advanced Point-of-Care Tool for Stratified Treatment in High Risk Cardiovascular Patients (PoCCardio)' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Cardiovascular diseases (CVDs) are the leading cause of death worldwide. Besides established risk factors such as elevated blood pressure, blood glucose or lipid levels, circulating proteomic as well as genetic markers allow further stratification of patients. While some of these markers can be measured routinely in low-threshold healthcare institutions, others require access to highly specialized and costly laboratory environment which usually can be found only within larger tertiary settings. The aim of this project is to advance and tailor a point-of-care (PoC) tool, which was recently developed within the framework of HORIZON 2020. Using cutting-edge lab-on-a-chip (LoC) and microfluidic technology, the tool will be further developed to measure qualified biomarkers and polymorphisms from finger prick blood, in order to help identify, classify and monitor cardiovascular patients at high risk. The clinical validation of these biomarkers and the PoC tool will then be performed in a prospective, randomised multinational trial which will include only existing and approved pharmaceuticals. Based on their specific pattern of qualified biomarkers, patients will be assigned either to standard pharmacological treatment, or tailored intensified treatment. Data derived from the clinical validation study will constitute a rich source for complex AI-powered computational analysis to explore potential predictors for primary and secondary outcome parameters. The trial will further provide the scientific foundation to support regulatory authorities in regard to approval of companion diagnostics, and recommendations for the prescription of drugs, respectively. Overall, this project aims to improve care and treatment efficacy in CVD patients through an advanced biomarker-driven PoC-bas
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Accelerating breakthrough Innovation to monitor, control and reduce Methane emissions.'.

assistant: **Concept**

Reducing global warming is the key challenge we must face in the next years. Methane (CH4) accounts for a third of temperature increase resulting from greenhouse emissions. Countries worldwide have collectively signed the Global Methane Pledge to decrease CH4 emissions by 30% by 2030. However, to date, existing data are both too expensive and not accurate enough to allow precise quantification and regulation of CH4 emissions. Absolut Sensing is building GESat, a satellite constellation to provide regulators and companies with accurate and affordable CH4 data. We achieve this thanks to ground-breaking innovations: a compact optical system, a miniaturized cryogenic spectro-imager and an AI-amplified data processing chain. Our constellation will reach a better detection threshold (>30kg/hour/CH4), revisit rate (daily measurement across all high methane emitting areas worldwide), and quantification precision (>95% regardless of weather conditions) at a better cost (<2€/km2).


**Keywords:** Methane detection, satellites, infrared sensor, data processing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'European Framework for safe, efficient and environmentally- friendly ship operations'.

assistant: **Innovation**

The overall objective of FLAGSHIP is to improve the safety, environmental friendliness and competitiveness of European maritime transport. The project will contribute to further increase in the capacity and reliability of freight and passenger services and to a reduction of negative impact from accidents and emissions. The emphasis of the project is on on-board systems and procedures, ship management systems on shore, impact of new technology on present ship owner and operator organisations, effective and efficient communication interfaces and impact of standards and regulations. Developments in legislation and reporting requirement represent new challenges in ship operation. From being an almost autonomous vehicle, modern ships are being turned into a component of highly controlled and monitored transport infrastructure. Requirements cover both certification of equipment, operation procedures and various recordings and documentation. Present ships are already being equipped with extensive systems for sensing, monitoring, diagnostics and decision support, and new communication infrastructures are being explored to provide a closer integration of ship and shore-based resources. However, due to the increasing complexity of onboard systems, combined with a n overall limitation in manning, the development of next generation shipping operations must be supported by relevant developments of technology, procedures and regulations. Modern ship systems are capable of providing a prodigious amount of data. There fore, it is essential that all the relevant information is presented to the ship operator in the best possible way, and that rational tools are available that give the ship crew and on-shore support teams intelligent guidance.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'EU-CHINA Lever for IPM Demonstration' in the context of a Horizon 2020 call.

assistant: **Objectives**

More sustainable pest management methods are needed in order to reduce the negative effects of pesticides on human health and the environment. The overall goal of EUCLID is to contribute to secure the production of food for the increasing worldwide population while developing sustainable production approaches to be used in the European and Chinese agriculture.The choice of the crops of interest in EUCLID, i.e. fresh tomatoes, table and wine grapes, and leafy vegetables (lettuces, cabbages, etc.), is based on their economic importance for both European and Chinese fruit and vegetable production, but also for their exemplarity in representing different production systems (field + greenhouse vegetables and ligneous perennial). This means that the solutions of the project could be used models for developing similar actions for other crops. The project is structured in 3 R&D work packages (WP), one WP dedicated to demonstration in field, one for dissemination and a WP devoted to project management.The project will exploit the thorough knowledge developed in the last years on IPM to adapt and optimize those tools and approaches which did not reach the field/market (yet). In addition, the consortium will work on the further development of high potential innovation pest management solutions.The consortium has been selected in order to integrate in the research process, from the very beginning, the main end-users of the project’s results: farmers associations, SMEs, economists, experts in policy. The consortium also has a good coverage of both European and Chinese experts, in order to take advantage of the experience of each region and to more efficiently adapt the pest management solutions to the specific problems of European and Chinese farmers.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Everyday Life Radar Sensors For Transportation'.

assistant: **Objectives**

Everyday Life Radar Sensors For TransportationIn the project ELIRAD we plan to further develop a cutting-edge radar sensor from the feasibility demonstration level to industrial readiness and maturity for market introduction. The developed sensors will support disruptive transportation applications and emerging markets. High-precision distance and velocity sensing is essential for a great variety of upcoming autonomous transportation systems like civil micro-drones, robotics, fully-automatic transport systems as well as autonomously driving cars. Silicon Radar (SiR) - with eight years experience in development and series production of radar chips - has developed a new generation of leading edge 120GHz radar sensors ideally suited for these systems. Our first-mover product will offer exceptional advantages and overcome drawbacks of current technologies. The sensor is a miniaturized but robust component for high-precision distance measurement; will consume significant less power, is dirt-immune and reliable; respects privacy. The radar sensor enables 360° true low-cost sense-&-avoid systems and thus will pave the way to wider acceptance of users and regulatory authorities. SiRs ultra-compact 120 GHz radar sensor is a result of the FP7-ICT project SUCCESS. Various prototypes where built; samples and evaluation boards where shipped to hundreds of customers. The reactions were constantly overwhelming. Positive feedbacks came from several companies with wide spectrum of applications ranging from industrial precision measurement up to obstacle detection in transport.The objective of ELIRAD is (i) to finalize the technical concept of serial production of the 120GHz radar sensor (high volume packaging and test concept) and (ii) to run a full chip qualification process, addressin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Entrapment of Hypoxic Cancer by Macrophages Loaded with HAP' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The proposed project seeks to open a new research front within the field of drug delivery to the solid tumours. Unsatisfactory response of tumours to chemotherapy is mainly related to impaired diffusion of the anticancer drug because of decreased drug uptake due to poor vasculature. Moreover, the drug is not able to penetrate the most hypoxic sites. Cells from these ‘untreated’ sites are responsible for relapse and metastasis. However, these avascular regions attract macrophages that migrate even to areas far away from blood vessels. Therefore, they might constitute a unique delivery system of drug containing particles to these parts of the tumour mass. A promising example of such particles that could be used are ferritins, whose caged architecture allows for efficient drug encapsulation and whose uptake from macrophage cells has been well demonstrated. My recent ground breaking finding was that macrophages are also able to specifically and actively transfer these taken up ferritins (loaded with the compound of choice) to cancer cells. Thus, these preliminary results indicate the possibility to use macrophages to deliver ferritin encapsulated compounds directly to the tumour cells even in its hypoxic areas. Then, the use of hypoxia-activated prodrugs (HAP) which are selectively activated only in hypoxic regions will be exploited in order to make cancer therapy safer. However, the molecular mechanism of ferritin uptake by macrophages, their storage, and transport to the cancer cells represent key issues to be investigated and pave the way to the experimental design of the present project. In the present project, we will develop and characterize a completely new and modern approach to anticancer therapy and drug delivery. As such we expect to be able to precisely administ