RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Euroconference on Electronic Properties of Novel Nanomaterials' in the context of a Fifth Framework call.

assistant: **Objectives**

We plan a series of three EuroConferences on electronic properties on novel nanostructures. These conferences will combine tutorial lectures giving an overview of important aspects of the field with latest research contributions both oral and by posters. This format will allow us to eventually cover the whole field by tutorials and to follow the latest developments. Novel Nanomaterials are synthetic structures like fullerenes, carbon nanotubes, vanadiumoxide rods and scrolls. They present a bottom-up approach to nanostructures - as opposed to bottom-down from lithography and etching. Synthetic nanostructures are expected to replace or complement silicon and III-V semiconductor microstructures, when scientific, technological, or economic reasons will cause silicon technology to fall behind the famous semiconductor roadmap.Scientifically and from the technological point of view, cross fertilisation between semiconductor technology and molecular physics and synthetic chemistry will not only lead to new materials and application, but even help our understanding of very small silicon devices and push the limits of silicon technology further. But there are also immediate applications of novel nanomaterials, like light emitting devices for flat displays, nanoactuators (artificial muscles") and nano-sensors.ftp://ftp.cordis.lu/pub/improving/docs/HPCF-1999-00239-2.pdf"
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Modernist Diarists Writing Unstable Selves', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

MoDi will produce the first comparative study of European writers' diaries specifically focused on the early 20th century and self- expression. It explores if and how modernist writers adapted the novel ideas on personality, particularly the 'crisis of the self' described by philosophy from the end of the 19th century onwards, in private writing. The diary genre provides an ideal testing ground for this topic, as it inhabits a threshold between life and art which can provide narrative coherence for a disintegrated self and enter in a productive relationship with a modernist aesthetic of fragmentation and plurality. MoDi offers an unprecedented comparison of English, French, and Italian personal diaries of modernist writers with each other and with earlier diary classics, and analyses the results in light of end-of-century theories of personality. Its overall aim is to find out whether it is possible to identify a generationally-specific 'modernist' diary, whose mode of self-expression changed when ideas about the self changed. It will thus provide an innovative perspective on how self-writing evolved in decades of intellectual ferment, open a new field of comparative diary scholarship in a transnational perspective, and provide groundbreaking material to explore the diary's powers of self-formation. Completing MoDi will allow the fellow to strengthen her competence in critical theory and develop a methodology to handle an extensive corpus, becoming a specialist in comparative modernist diary studies and laying the foundations for an independent research career. The dissemination of MoDi's research results among academic and non-academic audiences will promote private writing as a resource to negotiate personal and collective identity and to encourage self-awareness of c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Translation in cellular context: Elucidating function, organization and regulation with near-atomic models in whole cells' to be submitted under Horizon Europe.

assistant: **Abstract**

Translation – the fundamental process of protein synthesis catalyzed by ribosomes - has been extensively characterized from a biochemical, structural, and mechanistic perspective. However, how exactly the translation machinery operates as an interconnected system of millions of ribosomes in cells is poorly understood. Within the cell, ribosomes associate with a multitude of regulatory proteins forming a variety of specialized complexes and distributing across cellular space in a manner that depends on cell state. What is the specific composition of those complexes, their significance, and their functional role? How are they defined and regulated by subcellular compartmentalization? How do they change in response to cellular stress? Our TransFORM synergy team brings together experts in method development for in-cell structural biology and the biology of translation to allow us for the first time to attack these fundamental problems. Building on our prior achievements, we aim to synergistically develop novel methods of cryo-electron tomography with imaging across scales in conjunction with crosslinking mass spectrometry and integrative structural modeling for near-atomic structure determination directly in cells. TransFORM will determine the ribosome structural and functional states across the translation cycle in human cells, following distinct 40S, 80S, and disomal particles (80S+80S), in and out of polysomes and across different protein synthesis regimes. We will uncover structural and compositional changes and regulatory mechanisms across cellular space, in adaptation to perturbations by stressors and during viral infection. Our model systems will span from single cells to organoids. TransFORM will provide a detailed and comprehensive in-cell map of the essential proc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'European network on the development of artificial nucleases'.

assistant: **Innovation**

One of the main future strengths of Chemistry lays its application to biology, and it is essential for Europe to be able to call on a strong nucleus of trained personnel capable of operating comfortably in this interdisciplinary area. The Network will operate in precisely this area. ENDEVAN will bring together leading groups in the several central relevant areas to train young scientists to think and work across the boundaries of conventional disciplines. Industry has a special need for researchers witch receive will be the acquisition of new skills by working in the laboratories of Network members. The amin formal Training Programmes will be based on regular Network Meetings and the specialised workshops, which will offer lecture presentations and practical training in specialist areas of Network activity. Young researchers will be expected to present their own work regularly in an informal but professional way, thus acquiring this essential skill as an integral part of a their training. A third activity, which will be made available to all young researchers appointed within the Network, is an exchange period spent working on Network research in the laboratory of another member. This is one of the most efficient and natural ways of inculcating new skills."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Global involvement of public research scientists in regulations of Bio-safety and Agricultural Biotechnology' (2002-2006) under Sixth Framework.

assistant: **Objectives**

The project proposal addresses the growing gap between public sector life sciences in agricultural biotechnology on the one hand and regulatory policies and public perceptions on the other. Public research in modern biotechnology aims at solving problems in food and feed production, health care and environmental protection, in particular in developing countries. Developments in the public research sector in modern biotechnology are closely dependent on the design and implementation of the regulatory framework for genetically modified crops at the national, regional and global level. Modern biotechnology can tribute to solving these problems only if the regulatory frameworks are science based, predictable, transparent and balanced. Not only the risks that go along with any technological innovation need to be addressed in governance but also the benefits need to be taken into account. To achieve this, it is crucial that policy makers, regulators and the general public are better informed about the objectives and progress in life sciences in agricultural biotechnology. versely, the public research sector itself needs to be informed about the developments in regulations relating to modern biotechnology and the implications for research, so as to be better aligned with broader policy developments for food security, environment protection and sustainable development. Science 4 BioReg aims to involve the public researchers in the EU as well as in developing countries, in discussions on international agreements and regulations on biotechnology, and will inform policy makers, regulators and the general public about the objectives and progress in public research in agricultural biotechnology. Science 4 BioReg will provide outreach to non-English speaking public researchers and wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Do consumers value food labels? An assessment of the impact of information and personality traits on the demand for food labels' (FOODLABELS) targeting Seventh Framework.

assistant: **Abstract**

In recent years, changes in economic, social, cultural factors, as well as in tastes and consumers preferences and the increasing availability of products are driving consumers to change their eating habits. Consumers are gradually assigning more importance to the diet-health relationship when making their food choices. They have also become more concerned with environmental issues. Health considerations and food safety rank first among the buying motives of food products. In addition, environmental protection, a controlled quality and the products` natural state are central reasons for purchasing organic food. Consequently, consumers face increasing information on health and nutritional food characteristics, an important amount of which is presented on food packages labels. Hence, the objective of the proposed research is to assess to what extent consumers would value the provision of multiple food labels, when making food choices. The specific objectives of the project proposed are: 1) to segment consumers into groups depending on psychological/personal factors (attitudes, lifestyle, environmental and ethic values, eating habits, lifestyles etc), 2) to identify food labels that Spanish consumer would value more than others, 3) to find the maximum willingness to pay (WTP) for food labels, and 4) to analyze how information and personality traits affect the consumer Willingness to pay. The experimental auctions methodology and surveys are proposed to undertake the overall objective of the project. Understanding how consumers value healthier food products is relevant in devising optimal strategies to improve consumer eating habits and to positively affect on health system’s expenditures. The further reason to carry on this proposed project is the dissemination of informat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Testbed for Worldwide Agent Network: Research and Development'.

assistant: **Concept**

The Agentcity vision is: An ambient proactive environment where heterogeneous autonomous and increasingly intelligent systems representing businesses, services and individuals are able to interact with each other in a peer to peer manner and enable flexible and dynamic composition of services. Knowledge, information and service sharing is effectively available to users and organisations. When new pertinent or innovative services are available they are immediately offered to the appropriate user. Services are automatically discovered and integrated at the right level of interaction. Ontology, security, reputation and trust services in the environment should further enrich the range of businesses and private interactions possible between agent peers. Furthermore, the environment should be open to allow new services and systems to be connected and integrated semantically by coming on-line automatically.Objectives:The primary objectives of this project are:(a) to create a realistic, decentralised open environment which enables high level semantic interoperability between systems to support formation of novel, dynamic value constellations,b) to build sufficient knowledge and understanding of dynamic open environments to enable transition to widespread usage in reliable commercial grade systems.The project addresses dynamic value constellations in Four ways:(1) Designing and deploying an open extensible network environment which can support heterogeneous service building blocks composable into new value added service(2) The integration of business services into the environment to support rich interactions(3) The bringing together agent level communication technologies to provide a unified framework for modelling dynamic application services and(4) Demonstration points to show
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Economic Advanced Shaping Processes for Integral Structures (ECOSHAPE)' (ECOSHAPE) under Sixth Framework.

assistant: **Objectives**

A future need for aircraft structures is the development towards an increased degree of integration to save weight and to reduce manufacturing costs. An actual target is the reduction of assembly cost (riveting process) by laser welding (e.g. fuselage) or integral machining (e.g. wing structures). For such new concepts the current manufacturing chain has to be altered, unifying the forming steps and shifting this new step further towards the end. This enables more processing (e.g. machning, pocketing, welding) in a flat condition to achieve the full cost reduction potential. With this approach, laser based forming processes offer huge economic potentials due to high automation possibilities and avoidance of heavy, large and costly forming tools, required for each of the numerous differently shaped parts of current cold and hot forming processes. The main project target is the development of such laser forming processes for integral fuselage and wing structures. Thus relevant laser parameters with respect to minimum material degradation on one side and maximum formable sheet thickness on the other side will be evaluated. This system will include online 3D shape measurement to enable straight-line laser forming to the required final geometry. The main innovation of the project is the combination of the simulation, the control system and the online 3D shape measurement to a tool offering a self correcting, reliable, quick, robust and thus economic laser forming process for Al based structures. Following measurable objectives are envisaged: * Forming stiffened structures to single curvature of 1250 to 3000 mm radii along stiffeners* Forming bi-axially curved structures with additional 10000 mm radius across stiffeners* Verification of estimated shell manufacturing cost redu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Gut microbiome-mediated activities of psychotropic drugs' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Mental illnesses are among the most prevalent health burdens, with major depression ranking fourth among the leading causes of disease worldwide. Although diverse psychotropic drugs are available, the delayed onset of drug action, high non-responder rates and frequent side effects still pose significant challenges. Several observations suggest the gut microbiome as major contributor to high inter-individual differences in drug responses. While there is evidence that these drugs lead to changes in the microbiome composition of patients, it has not yet been explored whether these effects are part of the drug mode of action and/or whether they contribute to side effects. The aim of this project is to investigate to what extent gut microbes are involved in the therapeutic outcome of psychotropic drugs by employing model synthetic and patient derived microbiome communities (from stool of drug responders, non-responders and healthy controls), and in vivo gnotobiotic mouse models. We will systematically characterize the reciprocal interactions between gut microbes and commonly used psychotropic drugs ex vivo – from microbial drug metabolism to drug-induced bacterial secretion of neuroactive compounds. For intriguing interactions, we will elucidate the underlying mechanisms and use the knowledge to design engineered microbiomes. We will then employ gnotobiotic knockout mice deficient for primary drug targets of psychotropic drugs and colonize them with microbiome communities carrying the different mapped traits to separate the contribution of drug effects originating from the microbiome from those of the host. Overall, our results will inform microbiome-guided therapeutic strategies whose improved efficacy we will test in vivo. Due to the transferability of the developed techno
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Tailoring the functional Capacity of Cytotoxic T cells for future Therapies' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Cytotoxic T cells have enormous potential for prophylactic and therapeutic interventions against problematic acute or chronic infections and against malignant tumors. A major obstacle to utilizing them effectively is our limited understanding of the molecular foundation that is necessary for CD8 T cells to fulfil their pleiotropic functions. Equally important is to find solutions supporting the robust and safe induction of large numbers of pathogen- or tumor-specific T cells and strategies for customized generation of T cells equipped with a functional capacity that are optimized to the often contrasting needs of particular diseases. For instance, anti-tumor immunity requires large numbers of highly activated effector T cells, while resting memory cells with high proliferative potential in combination with tissue-resident memory cells are thought to enhance protection against viral infections. Similarly, the challenge in treating chronic infections and tumors is to overcome the hypo-functional “exhausted” stage of T cells, but therapeutic induction of the same mechanisms to attenuate an aggressive T cell response could be vital for treating autoimmunity or immunopathology in fulminant liver or lung infections. Thus, to develop prophylactic or interventional strategies through which qualitative aspects of T cell function can be adjusted is a current key challenge in the immunotherapy and vaccine field. We seek to promote such activities by performing research that aims to significantly augment our comprehension of how molecular particularities translate into functional diversity. By taking advantage of 1) experimental systems that specifically mimic disease relevant T cell phenotypes, 2) approaches to assess molecular diversity at single cell level, 3) effective strategi