RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Minimal Invasive Light Automatic Natural Orifice Robotic Platform' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

In the world of surgical medicine there is a major trend towards minimizing the number and size of skin incisions necessary to execute surgeries. This is very appealing from patients’ perspective, reducing or completely eliminating abdominal wall aggression and reducing post-operative pain. Less invasive surgery is also a major component of shorter hospital stays and quicker return to day-to-day activities by the patient. This benefits the patient, the healthcare system and the social-economic environment in general.  Single Incision Laparoscopic Surgery (SILS) is seen as the new frontier of this ongoing trend. In a SILS procedure the surgeon operates exclusively through a single incision in the patient’s navel, leaving just one barely-visible scar. However, SILS is very challenging for surgeons, because of the major constraints imposed by both the mode of access and the limited technology currently available.  Valuebiotech (VBT) is an SME, spun off from Niguarda Hospital and AIMS Academy (Milano, Italy) and intends to address this problem through highly advanced robotics technology. This technology is designed to take the robot into the abdomen, and provide (intra-abdominal) the various tools necessary to perform a surgical procedure. The MILANO robot can be inserted via a single incision or natural orifice, and then, once inside the cavity, the robot positions itself to perform surgery.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Transgenerational regulation of glucose metabolism by noncoding RNAs' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

Obesity and T2D affect large populations and cause a decline in life expectancy if untreated. The pandemic proportion of obesity and inaptitude of anti-obesity approaches reflect our limited understanding of its complex environmental and genetic etiology. Genome-wide association studies revealed that disease-associated risk variants are often situated in those 98% of the genome not encoding for proteins. This noncoding genomic space yet does not reflect ‘Junk DNA’ but gives rise to >10,000 noncoding RNAs like microRNAs and long, noncoding RNAs (lncRNAs) that implicated in control of glucose metabolism and energy homeostasis also by the applicant (Kornfeld et al. Nature 2013). LncRNAs were paraphrased as 'Dark matter of the genome' due to their tissue-specific and dynamic expression that contrast their poorly understood role in gene regulation. In the 1st part of this proposal, we ask if lncRNAs regulate glucose metabolism and are involved in the obesity-associated dysregulation of insulin signaling in the liver, the major glucoregulatory organ in mammals. Using RNA-Seq and novel lncRNA prediction algorithms, we observed that obesity alters expression of 28 annotated and 15  hitherto unknown lncRNAs in two mouse models of obesity. To identify lncRNAs causally controlling glucose metabolism, we established a siRNA screening system that allows functional interrogation of >650 lncRNAs. These in vitro findings serve as entry for the generation of lncRNA knockout mice that are metabolically phenotyped. In the 2nd part, we hypothesize that germline ncRNAs could control the transgenerational consequences of paternal obesity as shown for lower organisms. This builds upon unpublished findings from our lab showing that obesity profoundly changes expression of germline ncRNAs. In-v
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Social and ethical aspects of digital identities. Towards a value sensitive identity management', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Digital identity management concerns the control of digitized information pertaining to a person. This type of information is usually referred to as `personal data’, or ‘personally identifiable information’. With digitisation and automation processes pervading virtually all aspects and domains of society, the routine registration of personal identifiable data is increasing exponentially. The implied risks and challenges to fundamental rights like privacy and non-discrimination are recognized on the highest policy levels, but as of today still poorly understood or analyzed. In view of the fact that ‘identity’ is also a key concept in contemporary social theory, and conceptualisations of the relation between technology and society, ethics and normativity, a field of enquiry emerges at the crossroads of contemporary theoretical, technological and societal developments representing opportunities for frontier research. The overall aims of the project are to increase understanding of the social and ethical aspects of digital identity management (IDM), to further theorising the concept of identity, and to contribute to the quality and social/ethical acceptability of technological developments. The project will achieve these goals by bringing recent insights gained from several disciplines (science and technology studies, surveillance studies, social and technology philosophy, computer ethics) to bear on actual developments in digital identity management, thus exploring novel ways to identify and articulate the issues concerned. With a series of interdisciplinary studies focussing on different application areas of IDM, we intend to produce more fine-grained knowledge of the ways IDM is implicated in contemporary transformations of identity. The programme will involve three comp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Detector-Modulator Technology Utilizing Epsilon-Near-Zero Materials at Cryogenic Temperatures'.

assistant: **Concept**

Photonic integrated circuit implementations hold great promise for quantum technology, but practical large-scale integration is limited by the capabilities and performance of key components for processing and measuring quantum information, particularly phase-shifters and single-photon detectors. Current modulators fall short due to either high losses, large size, slow speed, energy inefficiency and/or excessive heat dissipation, making them incompatible with superconducting cryoelectronics. In the other hand, while superconducting detector technology has seen significant progress, their integration into photonic circuits lacks the flexibility needed for dynamic (mid-circuit measurements, feed-forward) reconfigurability, as detectors need to be placed at the output of the network and classical data is only being retrieved at the final stage. Project D-TEC, addresses these challenges by exploiting a novel class of electro-optic modulator for quantum photonics at cryogenic temperatures, featuring the epsilon-near- zero (ENZ) effect. Specifically, indium tin oxide-(ITO)-based electro-optic modulators show a strong ENZ effect, which enhances the local optical field and produces a large refractive index change near the ENZ wavelength. When operated at liquid helium temperatures, two significant effects occur simultaneously. First, ohmic losses of ITO material are reduced, amplifying the local-field enhancement of the ENZ effect to unprecedented levels. Second, ITO exhibits superconductivity at critical temperatures below 5 K. It thus becomes possible to create phase modulators with performance far beyond the state-of-the-art and a completely novel type of single photon detector, with tunable photon absorption capabilities. These innovations enable fast, cryo-compatible circui
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Cellular Dynamics of Intestinal Antibody-Mediated Immune Response' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Vaccination is widely used to prevent human diseases by inducing the formation of cellular and antibody-mediated immune responses for induction of long lasting immunological memory. Although most studies focus on immune responses elicited against injected immunizations, the simplest delivery of a vaccine regimen is by oral administration. The cellular and molecular components of the antibody immune response in peripheral lymph nodes in response to immunization are well described, however, much less is known about the dynamics of immune cells in gut associate lymphoid tissues (GALT) and adjust intestinal mucosal tissues. In the proposed research plan I will implicate intravital in vivo imaging for analysis of the cellular component of the antibody immune response in intestinal tissues. My goals are: 1. To track germinal center (GC) T cells for prolong time periods in peripheral lymph nodes and GALT and determine if they enter the memory compartment. For this purpose I will develop a new photoactivation method for permanently labeling immune cells and fate tracing of their daughter cells. 2. To examine T-B interactions and their regulation by intraceullar signaling pathways in GALT and to determine where and when class switch recombination to IgA takes place. For this purpose I will use intravital imaging of fluorescent reporter mice. 3. I will analyze the dynamics of plasma cell migration from Peyer’s patches to the mucosa by implementing state of the art photoactivation and imaging techniques that allow prolonged cell tracking. I will also use photoactivation approaches for sorting plasma cells from specific intestinal layers and perform gene expression analysis. 4. I will develop a new method to study dynamics and fate of B cells specific for commensal microbes in the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'From the bottom-up: a physico-chemical approach towards 3D nanostructures with atomic-scale control'.

assistant: **Innovation**

It is a long held dream in nanoscience to synthesize materials from the bottom-up with atomic-level control of structure and properties, yet the fabrication of nanoelectronics still relies completely on top-down processing. Innovative schemes for bottom-up fabrication will be realized in this project by developing approaches for area-selective atomic layer deposition (ALD), a technique that has the potential to become the new paradigm of bottom-up processing because of its atomic-scale control. Current work on area-selective ALD focuses on the processing of planar substrates, while emerging developments in nanoelectronics and quantum computing require the fabrication of 3D nanostructured devices. Building on recent innovations in my lab, a multidisciplinary approach to area-selective ALD will be employed which combines vapor-phase dosing of inhibitor molecules as a chemical method and the exposure to directional ions from a plasma as a physical method. Fundamental understanding of the mechanisms of chemical inhibition will be acquired, and a new strategy for physical removal of defects will be developed. These methods will be employed on 3D substrates to enable the fabrication of future device structures. By bringing inhibitor molecules and the directional nature of plasma ions together, new flavors of selective processing will be invented including anisotropic or topographically-selective ALD, which opens up a new direction for the field of area-selective ALD. The synergy between my extensive expertise with in-situ reaction mechanism studies and plasma processing, my leading role in the field of area-selective ALD, and the group’s unique facilities for atomic-scale processing, offers a stepping stone to the long-awaited shift from top-down to bottom-up processing. More
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Horizon 2020: H2020-SGA-INFRA-GEANT-2018 (Topic [a] Research and Education Networking)', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The GN4-3 is the proposed project for the third Specific Grant Agreement under the 68-month Framework Partnership Agreement (FPA) established between the GÉANT Consortium and the European Commission in April 2015. This third phase of implementing the FPA is proposed to last 48 months and is a natural continuation of the work in GN4-2, building on the results and maintaining the overall objective of helping to raise European research to the next level, promoting scientific excellence, access and re-use of research data. GÉANT’s world-class, high-speed backbone provides seamless and secure connectivity with 42 National Research and Education Networks (NRENs), reaching over 50 million users in 10,000 institutions across Europe, and more than 100 countries worldwide through links with other regions. The core backbone is capable of multiple 100 Gbps transmission over each fibre link, and Terabit connectivity can be achieved by a single node. The safe and rapid connection of users to each other, to the increasing amounts of data generated by research, and to the high-performance computing capacity required by collaborative research form the foundation of the GÉANT partnership.GÉANT services offer convenient, fast and reliable access to European High Performance Computing facilities, cloud services for the research and education community, access to scientific data and publications and other services from the European e-infrastructure providers, whenever and wherever needed. The structure of the present proposal emphasises updating existing services in line with requirements of the user community. This complements the proposed companion project GN4-3N, an ambitious programme increasing the footprint of the backbone network at the same time as improving its capacity, resilience
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The European aeroemissions network' (AERONET) targeting Fourth Framework.

assistant: **Abstract**

AERONET PROJECT OVERVIEW One of the major problems that civil aeronautics will have to face over the next twenty or thirty years is to accommodate the predicted growth in demand of air transport without creating unacceptable adverse environmental effects. It is to be expected that new scientific results, increasing public concerns over the environment and future restrictive regulations with respect to aircraft emissions will force airline companies to take ecological considerations much more into account than it does at present. Consequently, for European aircraft manufacturers it is of high importance to react early and to guide their research and development resources into the most important and efficient direction. The aim of the AERONET project is to support coordination ' a postiori' of existing European and national projects or programmes dealing with the contribution of air traffic emissions to anthropogenic climate and atmospheric changes. For this purpose AERONET seeks to : * bring together experts from engine technology, atmospheric research and operations as well as programme responsible to exchange knowledge and opinions and to discuss necessary future actions on the basis of jointly defined goals and time scales, * produce competitive advantage for Europe through enhanced information echoing in the field of atmospheric effects of air traffic emissions, * strengthen a common European position in global technical and political discussions * support the Commission in identifying topics for the 5th Framework Programme, * identify gaps and help prepare a coordinated submission of proposals. EUROPEAN DIMENSION AND PARTNERSHIP Europe is, beside the US, one of the two biggest aircraft manufacturers. One supposition for the economic success of European aircraft indu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'BusUp: Multi-platform On-demand Crowdsourced Bus Transportation for Smart City Mobility'.

assistant: **Concept**

BusUp is an innovative concept in smart mobility that allows travelers to book on-demand crowd-sourced buses for leisure and commuting.Users are able to setup their own routes in the web-platform and app. They can share them with their friends and colleagues, or can make them public on the platform or social media for anybody join. BusUp is also available for B2B clients that want to create their own routes through a dedicated web platform.BusUp was created to solve a need in medium-distance travel: commuting in suburban and exurban areas, or traveling to events like music festivals and sports events located in city peripheries or neighboring towns - essentially anywhere public transport is limited or non-existent, and where the car is the only option despite the fact that it’s more expensive, less sustainable, or simply no fun.While on-demand bus transportation solutions are already growing in the United States and India, they are only now starting to emerge in the EU, and are limited by their technology and business models. By employing proprietary artificial intelligent algorithms that determines optimal pick-up times, locations and vehicle routes, in combination with crowd-sourced payment modules, BusUp is able to offer one of the most innovative solutions in collective road transportation.By using BusUp users will be contributing to the reduction of congestion and pollution, while joining a community of like-minded travelers who want to enjoy the ride.Our current platform, BusUp 1.0, has been extensively tested with local bus operators and passengers in Barcelona for over 4 months and has already started to serve its first paying customers. BusUp has already reached a commercial agreement to internationalize and to operate in Sao Paulo (Brazil) in 2017.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Short-wave infrared photodetectors based on low-cost, environmentally friendly InSb colloidal quantum dots' (ECOSWIR).

assistant: **Innovation**

The development of low-cost optoelectronic devices in the short-wave infrared (SWIR, 1-2 um), would open up a huge number of applications, such as 3D and adverse weather imaging, night vision for surveillance and automotive safety, chemical hazard detection, environmental sensing, and biomedical diagnostics etc. leading to a direct and huge impact on quality of life, health, and security, provided that such technologies are available at low cost and high volumes, to serve consumer electronics markets. To address this large consumer market volume the necessity for low-cost, non-toxic, and complementary metal oxide semiconductor (CMOS) compatible SWIR photodetectors is therefore indispensable. To date, the SWIR has been served by costly epitaxial III-V semiconductors, which are not monolithically integrated to silicon (CMOS) electronics, and suffer from high growth cost and low volume manufacturing. Compared to epitaxial technology, solution-processed technology based on colloidal quantum dots (CQDs) is more promising for SWIR photodetectors due to low cost and high volume manufacturing, and their CMOS integrability. On the other hand, InSb is an environmentally friendly III–V semiconductor which possesses a narrow direct band gap and the highest room temperature carrier mobility, and the smallest exciton binding energy of all semiconductors, thus being ideal for SWIR photodetectors. Therefore, ECOSWIR aims to develop a whole new material platform based on non-epitaxial InSb CQDs that, in contrast to current III-V technologies, will enable CMOS compatibility and large-scale production of optoelectronic materials.Utilizing this achievement, ECOSWIR will provide a proof of principle of InSb CQDs SWIR photodetectors with performance that cannot be met by any prior CQDs devic