RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Presidency Conference on Access to Finance for Research, Innovation and Growth' in the context of a Horizon 2020 call.

assistant: **Objectives**

The Innovation Union (IU) is a flagship initiative of the Europe 2020 Strategy which has a central role in achieving the goals of the Europe 2020 Strategy for a smart, sustainable and inclusive economy. It is aimed at improving conditions and access to finance for R&I in Europe, to ensure that innovative ideas can be turned into products and services that create growth and jobs. The IU contains over thirty action points including a key point for ‘Enhancing access to finance for innovative companies’. According to the EC’s proposal, the EU needs to put in place financial instruments to attract a major increase in private finance and close the market gaps in investing in R&I. Horizon 2020 is the financial instrument aimed at implementing the IU. By coupling R&I, Horizon 2020 focuses on excellent science, industrial leadership and tackling societal challenges. Under the 'Industrial Leadership' pillar, Horizon 2020 supports companies and other organisations engaged in R&I to gain easier access, via financial instruments, to loans, guarantees, counter-guarantees and hybrid, mezzanine and equity finance.Currently, the priority is to continue and build on activities that have been worthwhile in supporting R&I in 2007-2013 such as the RSFF, the RSI for SMEs and GIF-1. Horizon 2020's financial instrument facilities will also operate in conjunction with those of EU programme COSME, and the coming two years will see, a significant participation by Horizon 2020 in the proposed SME Finance Initiative; the launch of a pilot facility supporting the technology transfer process; and a new focus on improving access to risk finance by larger midcap firms.The overall objective of the conference is to raise awareness of the financial instruments, facilities and accompanying measures launche
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Geochemical-physical coupled study of the modern Arctic Ocean: GEOTRACES-ARCTIC'.

assistant: **Concept**

Climate-driven alterations of the Arctic Ocean (sea ice cover, hydrography, circulation) strongly influence biological productivity and ecosystem structure. At present, our ability to evaluate the full impact of these changes and predict their future trajectory is limited by a poor understanding of the interacting chemical, physical and biological processes which shape the functional characteristics and resiliency of Arctic waters. To bridge this critical knowledge gap, a pan-Arctic field study (Arctic-GEOTRACES) is being coordinated between Canada (2015), US, Germany and France to generate a quasi-synoptic database of biogeochemical tracers in relation to circulation and ecosystem structure and productivity. The Canadian program involves 28 investigators including biological, chemical and physical oceanographers, experimentalists and modelers.Fully integrated in this program, the proposed research focuses on tracers of ocean circulation and land/ocean chemical exchanges (Rare Earth Elements, ENd, 230Th, 231Pa), both impacted by climate change in the Arctic. It will be conducted on the Canadian section, from the Canada Basin to the Labrador Sea, and consists of a three-step approach:1) Modelling study of Arctic Ocean dynamics, including off-line Lagrangian analyses to refine the sampling strategy for the tracers above-mentioned;2) Measurements of these tracers on the Canadian section to specifically investigate land-ocean exchanges and circulation; 3) Integration of these data into a fine resolution model coupling circulation, sea ice dynamics and biogeochemical processes to refine our understanding of circulation and to quantify land-ocean margin chemical exchanges of bioactive or water mass fingerprinting chemical elements.Besides enriching international databases, re
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for '(Re)constructing a Bible. A new approach to unedited Biblical manuscripts as sources for the early history of the Karaim language' (Re).

assistant: **Innovation**

Eastern European Karaims are the sole representatives of Karaite Judaism in Europe. Their native tongue is a severely endangered Turkic vernacular listed on the UNESCO Atlas of the Worlds’ Languages in Danger. Due to many historical events, including World War II and the Soviet era, the cultural heritage of this intriguing ethnic minority suffered great losses. At the same time, since its investigation requires a rare combination of unique linguistic and palaeographic skills merely a fraction of its surviving written heritage has entered scholarly circulation. In particular, no comprehensive edition of the Karaim Hebrew Bible exists, even though nearly 100 Karaim Biblical texts have been discovered to date.The project will construct a digital edition of the entire Karaim  Bible, almost exclusively based on unedited texts in Hebrew script (15th–20th cc). It will be used as a tool to deliver the first linguistic and palaeographic descriptions of the oldest, still unedited records of Karaim as well as reconstruct the way in which the Karaim Bible was created. Combining traditional and computer-aided research methods will provide essential data on the early history of the Karaim language and ethnicity. The edition will be a highly complex instrument interconnected with a dictionary, which is an absolute novelty in the field.The edition will contain the first ever comprehensive Karaim translation intelligible to present-day native-speakers. The texts will be treated according to the principles of textual criticism and translated into English. If permitted, facsimiles will be provided. One exciting aspect of the enterprise is that it will offer a virtual unification of the Karaim translations of one of the most important and influential works in world literature. Such a task
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Application of space techniques to the integrated management of a river basin water resources' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

The main aim of ASTIMwR project is to develop an application devoted to the integral management of the water resources of a river basin making use of the data provided by Earth Observation Satellites. To achieve this objective, the Guadiana river basin has been selected as the pilot area. The Guadiana basin has a wide range of troubles that cover several fields: administrative, socioeconomic, environmental, hydrologic and hydrogeologic. For this reason, the application that will be developed, will be susceptible to be extrapolated to other river basins. The general objective we have proposed can be divided in a series of partial objective covering the resolution of the troubles existing in the Guadiana basin: - Analysis of the operational needs of the customer organizations and the value-added supplied to by the EO-derived information. Identification of a suitabdata supply chain and suitable processing schemes to derive the requiredinformation. - System design. Ellaboration of the subsystems to implement. - Evapotranspiration mapping. - Irrigation performance monitoring. - Management of exploitation regimes in overexploited aquifer areas. - Monitoring of the hydric evolution of Wetlands related with the developmentof irrigation in the surrounding areas. - Development of a pilot system devoted to manage data and generate basicinformation that might be used at the customer organizations. In order to fulfill the objective of applicability of the system to be designed the project to other areas with water management troubles, a second river basi (Sele rive basin, Italy) has been selected for extrapolation of the system. The previous objectives have been organized in 8 Work Packages (WP'S): WP0 Project Management( GEOSYS) WP1 Definition study (ITC) WP2 System design (ITC/GEO
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'TRACTOR' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

To assist the creation and consolidation of innovative start-ups by integrating and formalising new practices, supplying support services and providing training.Description of the work:Start-ups face several problems, even when they are successful in their commencement. Only a small number of innovating start-ups survive and grow after the first three to five years. There are also many troubles that hinder the rising of new companies from good innovative ideas of entrepreneurs, including lack of access to finance, lack of skills, obstacles to sales activities and administrative burdens.The Tractor project, which is to be implemented in regions within Spain, Sweden, France and Slovenia aims to integrate and formalise the new practices resulting from the creation and development of new innovative enterprises across Europe. The principal objectives are to increase the existing start-up creation rate, thus reducing the gap between Europe and the United States. The success rate of start-ups by the end of the project is targeted at being between 40% and 60%, which would mean making considerable increases from the current rate, which is between 10% and 30%.Principally, the scheme will function via 'action programmes' that will provide guiding materials, e-learning facilities and procedures and remote assisted support. The project co-ordinators will collect feedback from the regions involved and this will allow analysis of the action programmes and validation by using pre-defined impact indicators. The aim is for the validation process to lead to the formalisation of new best practices that can then be implemented throughout Europe.The main target group of Tractor will be those start-ups of 3-5 years of age as they are in the highest risk category. Support will be offered in re
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Design of sandwich structures for sensor integration, optimisation and manufacturing of sandwich core'.

assistant: **Innovation**

Evonik proposes to contribute to the evaluation of the strength of foam sandwich structures, as demanded in the Call for Proposal (CfP), by providing a failure criterion, which has been designed specially for ROHACELL® foams in cooperation with the German Institute for Polymers (DKI) in Darmstadt. This criterion has been proved to deliver very accurate results in static FE calculations and might be used as a basis for extension to calculate impact and fatigue loads. Evonik has profound knowledge and experience in the field of manufacture and supply of raw and shaped foam core materials meeting the requirements of the aerospace industry, which Evonik proposes to supply as demanded in the CfP. Evonik has the facilities to produce raw foam cores as well as to shape these cores to the desired geometry, e. g. by using cutting and CNC machining equipment. Furthermore Evonik possesses the infrastructure needed for the quality control and documentation which is mandatory for aircraft applications. ROHACELL® foams offer superior heat and pressure stability up to 180°C and 7 bar as well as a one hundred percent closed cell structure, which eliminates excessive resin absorption and thus reduces overall weight. Evonik possesses an autoclave, which is proposed be used for the manufacture of sandwich panels, e.g. using prepreg face sheets. Evonik proposes to contribute to the development of special design rules considering SHM-requirements, as demanded in the CfP.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Making forest asset management easy' (WUUDIS) targeting Horizon 2020.

assistant: **Abstract**

In Europe, 60% of the forest area is owned by private individuals, who mostly live in cities, not even knowing where theirforestry is located. These remote forest owners lack easy tools for understanding and taking control of their forest assets inorder to perform proper silvicultural management practices and to harvest and to sell valuable timber and thus contributing tothe European economy. Also, as EU forests are under threat by rapid climate change and invasion of alien animal species,major concern of forest authorities is how to encourage forest owners to better manage their assets. MHG developed Wuudis, a cloud-based web service and a mobile solution for forest owners and contractors to effectively manage forest resources remotely in real-time.Wuudis provides information about the forest and its timber resource; track of executed silvicultural activities andguidance for planning next forest activities that need to be performed in order to gain economic benefit from timber harvest.It enables easy scouting and connection between forest owners and contractors to close e-contracting deals, which savescosts and increases margin for contractors. It also provides automatic reporting and sharing of damage on wood by weather,soil erosion and diseases.In Phase 1, MHG will assess the economic viability through a realistic bottom-up approach in which the number of reachableforest owners and contractors will be estimated according to in progress and existing contacts with stakeholders in the forestindustry. The technical viability will be assessed through the involvement of organizations (government, profit or non-profit) with access to national electronic forest data and GIS data in Finland, Czech Republic, Spain and Belgium.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Mechanisms for the regulation of Carotenoid production and accumulation in plants' to be submitted under Fourth Framework.

assistant: **Abstract**

The proposal utilises the skills of six laboratories to answer critical questions necessary for advancing our understanding of carotenoid formation and deposition in plants and to address the potential for its manipulation for agricultural, industrial and nutritional purposes. The work will focus upon increasing our knowledge of the biochemistry and regulation of carotenogenesis, its integration and inter-connection with other isoprenoid pathways in order to provide for the widespread manipulation of carotenoid production and accumulation in crop plants. There are two objectives in the proposal: 1. To elucidate the regulatory mechanisms controlling carotenoid formation in green and non-green tissues of higher plants, encompassing the pathway from early precursors. 2. To clone and characterise novel structural genes and regulatory elements involved in carotenogenesis in plants. The project has two integrated work packages, which utilise a range of higher plants in order to encompass the complexity of regulatory events thought to control carotenoid formation and deposition. A multi-disciplinary approach will be used, covering biochemistry, molecular biology, and analytical chemistry, with considerable use of plant transformations. Workpackage 1 deals with elucidation of the mechanisms controlling carotenogenesis and accumulation, including regulation of gene expression, compartmentation of enzymes and substrates, properties of enzymes, metabolic fluxes, inter-pathway cross-talk and the influence of storage proteins on carotenoid accumulation. It also aims to establish the presence and importance of an alternative pathway to isopentenyl pyrophosphate. Workpackage 2 incorporates cloning and characterization of novel structural genes and regulatory elements in chromoplast an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Selective Inhibition of Bacterial Intramolecular Trans-Sialidases via a Multidisciplinary Computational/Experimental Approach' (SELECT-IT) under Horizon Europe.

assistant: **Objectives**

SELECT-IT aims to develop small molecules that specifically target bacterial intramolecular trans(IT)-sialidases. IT-sialidases from Ruminococcus species have been related to progression of inflammatory bowel diseases (IBD) and colorectal cancer (CRC). Following elucidation of the yet unknown mechanisms of action of IT-sialidases, I will rationally design candidate inhibitors, synthesise and characterise them, and assess their binding modes, inhibition efficacy and target selectivity. Inspired by strategies previously successful for antiviral drugs like Tamiflu, SELECT-IT will modify existing molecules such as Siastatin B, DANA, and 2,7-anhydro-Neu5Ac, as starting points to develop candidates that selectively inhibits bacterial sialidases while sparing human ones. The inhibitors will undergo systematic refinement through computer simulation (molecular dynamics, QM/MM and metadynamics) and experimental techniques (biochemical assays and NMR spectroscopy) to ensure high specificity. SELECT-IT aims to develop targeted inhibitors for managing bacterial infections linked to IBD and CRC, contributing directly to the creation of new therapeutic options.


**Keywords:** Drug design, Enzymatic reactions mechanism, CAZymes, neuraminidases
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Validated predictive dynamic models of complex intracellular pathways related to cell death and survival' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

VALAPODYN seeks to advance the development of multidisciplinary functional genomics relating to complex biological processes & cellular networks. The project concerns both DNA & protein applications, followed by innovative dynamic modelling of pathological disease states such as epilepsy, cancer in order to validate the model. The overall aim is to develop an innovative System Biology approach in order to model the dynamics of Molecular Interaction Networks (MIN) related to cell death & survival in the organism. The future dynamic model will be dedicated to selection of drug targets designed to treat human pathologies such as epilepsy, cancer, neurodegenerative diseases. The overall result of dynamic modelling will be an immediate selection of the most efficient putative therapeutic targets, decreasing by at least 10 times the number to study & thus increasing cost effectiveness. S&T objectives are: Pathways analysis: functional annotation of genes & proteins, investigation of structure & dynamics of signal transduction & transcription regulatory networks.; Predictive bioinformatics platform for dynamic modelling: to use innovative biomathematics/bioinformatics to integrate experimental MIN data with biological tissue & pathological states data obtained through the use of transcriptomic & proteomic approaches.; Bioinformatics: to set up a highly specialised database on genomics & proteomics of MIN modelling.; Pathological tissue & animal models: to use novel animal models to evaluate local expression genes/proteins in neurodegenerescence.; Microarrays: to set up a network of microarrays using the Codelink platform.; Proteomics: to form a network of advanced quantitative methods in proteomics technologies (MALDI, ICAT, 2-DPAGE, Heavy Peptides isotopic dilution).; Neuropr