RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Music between Arabic and Greek Texts: A Study of the Science of Harmonics in Islamic Thought (9th-11th c. CE)'.

assistant: **Concept**

The project aims at giving a complete and complex study of the science of harmonics within the Islamic philosophical tradition. In centuries 9th-11th CE, harmonic science develops as one of the four mathematical sciences of the Ulum Riyadiyyah (Quadrivium), as a philosophical discipline largely independent of musical practice. The discovery and the translation of the Greek harmonic sources, thanks to the mediation of Byzantine erudition, are the driving force behind the emergence of harmonic science in Islamic thought. Through a philological approach, which involves a critical examination of the six main Arabic texts that represent this phenomenon, their translation, and a textual and content comparison with the Greek sources, an overall philosophical framework of Islamic harmonics will be provided. The six pivotal Islamic sources are al-Kind, Hunayn ibn Ishk, the Ikhwn al-af (The Brethren of Purity), al-Frb, al-Khwrizm and Avicenna. The project includes also the lemmatisation of the selected texts: through the concordance software AntConc, each text will be compared to the lemmas database, enabling linguistic analyses, and enriching the literary inquiry. The overall framework of Islamic harmonic theory aims at being broad in scope: it will encompass the distinctive features of the exposed theories, the ideological objectives, the utilization of Greek sources, and the intellectual context in which the phenomenon develops.


**Keywords:** Islamic Philosophy, Arabic Literature, Mathematical Sciences, Science of Harmonics, ancient Greek Literature, ancient Greek Science, Byzantine Reception
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Decoding the organization and regeneration of locomotor neuronal networks in tetrapods by integrating genomics, systems neuroscience, numerical modeling, and biorobotics'.

assistant: **Concept**

The goals of this project are to decipher how the interplay between central and peripheral mechanisms controls locomotion in four legged animals (tetrapods) and to the delineate the reorganization of motor circuits linked to functional regeneration after spinal cord lesion. We will take advantage of the evolutionarily conserved traits of neural structures in vertebrates to address these two fundamental questions by using salamanders as model organisms. Salamanders are best suited to these aims for two main reasons: First, because they have an anatomically simplified nervous system, which yet possesses the main features of all tetrapods; second, because they have unique regeneration abilities among vertebrates and can functionally repair their spinal cord after full transection. Taking an interdisciplinary approach, we will investigate the dynamic interactions between the nervous system, the body, and its environment before and after spinal cord lesion. We will combine numerical models of locomotor neural circuits, robotics, and advanced functional analyses in genetically modified salamanders in a way that will allow us to test biological data in neuromechanical models (simulations and robots) and, conversely, to validate model-based predictions in animals. Through the concerted and tightly collaborative activities in our laboratories, implementing state of the art assays ranging from the molecular to the organism level, we expect to create a blueprint of tetrapod locomotion control: how appropriate movements are generated in response to various environmental or intrinsic stimuli, and how such function can be recovered after injury. The synergy between our groups of complementary expertise will boost scientific research at multiple levels, not only in the field of neuros
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Energy Services for Multi-user Business Parks with Enchanced Levels of Renewables and Rational Use of Energy - Target Action I' (ENSURE), addressing dissemination and exploitation.

assistant: **Impact**

This proposal aims at enhanced RES/RUE integration in multi-user business parks through application of virtual energy management systems. Specific objectives are:1. Development of a simulation model for business park developers for optimisation of RES/RUE integration. The model will give optimum strategies for RES/RUE integration and for demand side and load management of multi-user business parks;2. Development of an internet-based automated virtual business park management system for integrated resource planning and control, optimised for multi-user business parks in terms of organisation, economic viability, maximum renewable energy integration and greenhouse gas emission reductions;3. Environmental and economic targets, tested and monitored at pilot sites: 25% energy cost reductions; 15% RES share; 20% CO2 emission reductions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Structure and function of p-glycoprotein which confers multidrug resistance on cancers'.

assistant: **Innovation**

Resistance to chemotherapy causes tens of thousands of cancer deaths in Europe each year. One protein, the multidrug resistance P-glycoprotein encoded by the MDR1 gene, can confer multidrug resistance on cells and tumours, acting as an ATP-dependent transporter to pump drugs out of cells. This project will contribute to our understanding of the structure and function of P-glycoprotein. A detailed understanding of the mechanisms by which this transporter acts is not only of fundamenal scientific interest and importance, but may contribute to the develpoment of improved antitumour agents. The project will involve site-directed mutagenesis to introduce single cysteine residues into specific sites on P-glycoprotein and labelling these residues with fluorescent or spin labels. A biophysical study of these labelled proteins, together with electron microscope imaging techniques, will allow a detailed model of the structure and function of this protein to be developed. Necessary preliminary work and method development for this project have already been completed and the project will provide training in a range of molecular biology, protein chemistry and biophysical techniques.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Metabolic requirements for prostate cancer cell fitness'.

assistant: **Concept**

The actual view of cellular transformation and cancer progression supports the notion that cancer cells must undergo metabolic reprogramming in order to survive in a hostile environment. This field has experienced a renaissance in recent years, with the discovery of cancer genes regulating metabolic homeostasis, in turn being accepted as an emergent hallmark of cancer. Prostate cancer presents one of the highest incidences in men mostly in developed societies and exhibits a significant association with lifestyle environmental factors. Prostate cancer recurrence is thought to rely on a subpopulation of cancer cells with low-androgen requirements, high self-renewal potential and multidrug resistance, defined as cancer-initiating cells. However, whether this cancer cell fraction presents genuine metabolic properties that can be therapeutically relevant remains undefined. In CancerMetab, we aim to understand the potential benefit of monitoring and manipulating metabolism for prostate cancer prevention, detection and therapy. My group will carry out a multidisciplinary strategy, comprising cellular systems, genetic mouse models of prostate cancer, human epidemiological and clinical studies and bioinformatic analysis. The singularity of this proposal stems from the approach to the three key aspects that we propose to study. For prostate cancer prevention, we will use our faithful mouse model of prostate cancer to shed light on the contribution of obesity to prostate cancer. For prostate cancer detection, we will overcome the consistency issues of previously reported metabolic biomarkers by adding robustness to the human studies with mouse data integration. For prostate cancer therapy, we will focus on a cell population for which the metabolic requirements and the potential of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Tobi - towed ocean bottom instrument' to be submitted under Fifth Framework.

assistant: **Abstract**

Description:EASSS III offers access to 3 unique instruments for seafloor survey. TOBI is a deep-tow geophysical survey vehicle, carrying sidescan sonar, profiler, magnetometer and CTD instruments, for use in water depths between 200 and 6000 m. On research cruises where TOBI is the primary tool, one of two additional instruments, BRIDGET and SHRIMP, which compliment and increase the scientific value of TOBI, is offered in an integrated package. BRIDGET is a deep-tow instrument for the investigation and sampling of submarine hydrothermal plumes and water mass properties.SHRIMP is a real-time deep-tow camera platform, used for ground truthing TOBI sidescan images. Data processing using state-of-the-art software developed at SOC, and scientific training in survey design and data interpretation are also offered, both at sea and for post-cruise work at SOC. Use of the infrastructure is offered on 3 research cruises of up to 30 days each over 3 years. A total of about 30 researchers will benefit. Details on how to apply for access are available through the EASSS website (http://www.soc.soton.ac.uk /CHD/Easss3/index.html). All access available under EASSS III has now been allocated.Application:A call for proposals, deadline 15th May 2000, is now available at the website above.Project Manager:Douglas Masson, Southampton Oceanography Centre, European Way, Southampton SO14 3ZH, United Kingdom;Tel: +44-1703-596568;Fax: +44-1703-596554;E-Mail: d.masson@soc.soton.ac.uk
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Joining forces to exploit the mycobiota of Asia, Africa and Europe for beneficial metabolites and potential biocontrol agents, using -OMICS techniques' (MYCOBIOMICS) targeting Horizon 2020.

assistant: **Abstract**

The proposed project embarks on a previous collaboration in the framework of H2020-MSCA-RISE “GoMyTRi” that has successfully laid the groundwork for an international collaboration involving three worldwide leading research infrastructures from Germany, the Netherlands, and Thailand. The common research interest of the partners is basic and applied mycology, and they joined forces to explore the beneficial secondary metabolites for development of antibiotics, and to find potential candidates for development of environmentally friendly fungal biocontrol agents. The interdisciplinary training conducted in the course of “GoMyTri” has already resulted in several joint scientific publications, and some of the PhD candidates involved have graduated with excellent grades, while some of the postdoctoral researchers involved have gained valuable experience in project management. During the past years, the collaboration has been consolidated and the partners have also been changing the scope of their respective research agendas. The new proposal aims to expand the collaboration by adding further, carefully selected partners from Austria, the Czech Republic, Kenya and South Africa, which have an excellent scientific track record and bring in additional know-how and expertise. The new objectives have been expanded to the implementation of –OMICS technologies and studies on the interaction of fungal organisms in order to discover newbioactive molecules. Furthermore, the project aims at characterization of the mycobiota of important agricultural plants. The scientists involved in the training program will thus be working in an interdisciplinary scenario that is intended to tackle several important global challenges at once and be given the opportunity to learn many important methods a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'SW for: storage of various music input, conversion of different Braille syntax into sound, graphic, Braille output and telematics access' in the context of a Fifth Framework call.

assistant: **Objectives**

PLAY2 is an extension of PLAY (under DGXIII - Telematics Applications Programme), which was completed in 1999.PLAY developed:the PLAYcode, to manage and file Braille music in compliance with Braille rules and syntax, as stated in the International Manual by the World Blind Union;the Braille Music Editor (BME), to write and convert music in PLAY code;to convert from and to codes such as Enigma (Finale), MIDI, NIFF;and an OCR prototype for raised Braille.PLAY2 aims at:starting some web sites with electronic library and search system;acquiring new Braille Music Code pieces, by translating Braille texts and transcribing 20th century ones (little is available in Braille), in compliance with copyright rules;advertising the project and providing blind musicians with a free new BME editor for the entire project duration;activating and managing the service and regularly informing all people involved about the project progress;Braille Music Code advertising and dissemination activities;and monitoring any sites and initiatives using PLAY2.DESCRIPTION OF WORKPLAY2 was generated from the needs of the users showing a great interest in PLAY. PLAY2 will enable them to organise their own virtual libraries, so as to receive more and more texts, to collaborate and exchange scores with sighted musicians. The whole PLAY2 activity will enable the institutes and libraries participating in the project to collect more and more material. These institutions will continue to collaborate in the initiative, even after the project completion.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Vascular Optical Tomographic Imaging System” We help diabetics keep their feet'.

assistant: **Objectives**

Epidemiological studies confirm a link between diabetes and increased PAD (Peripheral Arterial Diseases) prevalence, anddiabetes is associated with a two- to four-fold increase in PAD compared to non-diabetics. PAD impedes resolution of smallsurface wounds and is an important predictor of diabetic foot ulcers (DFUs). DFUs are a chronic complication of diabetes.Recent studies suggest that diabetics have a 25% risk of developing a DFU over their lifetime, and when a person with PADdevelops a DFU, often the DFU will not heal. Therefore, the physician who examines a patient with diabetes and foot ulcershould always assess the vascular status of lower limbs. Nevertheless, PAD detection and the assessment of its severity isa clinical challenge in diabetic patients with foot disease, due to altered clinical presentation of PAD and limitations of thediagnostic procedures: many methods analyse only the outer surface of the sk VOTIS utilises an innovative, non-invasiveand patented methodology to assess the physiological health of the lower limb even before tangible symptoms appear.“Time is tissue.”VOTIS aims to promote necessary changes in the armamentarium for treating peripheral artery disease(PAD), ischaemia and low perfusion rates in diabetics. These changes support detection and preventative healthcare andwill improve control over disease progression. This, in turn, will lengthen the path to necessary amputations and reduceassociated health consequences and their costs. Our business opportunity is very attractive, considering the growingnumber of diabetics at risk for foot amputations as well as the limited ability of currently-available solutions to detect, locate,and quantify the severity of peripheral artery disease (PAD). We plan to increase our understanding of internat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'New small scale innovative energy biomass combustor', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

Innovative combustion system: Compared to conventional grate-fired boilers, cost reduction min. 33%, from 175-235 EUR/kWth to 115 EUR/kWth (compact construction of the boiler, no refractory material); Low stack loss, boiler efficiency 3 % points higher; Equalised temperatures within furnace (high degree of turbulence); very compact combustion chamber; More complete combustion, even in the case of inhomogenities.Scale up: Cost reduction by min. 33%, specific investment cost below 1500 EUR/kWel (simplification of every step; replication); net electric efficiency + 3% points; Thermal peak load coverage without increasing of rated power, electric power peak load coverage; Reduction of emissions (operation near the optimum). Demand side mgmt.: Complete new district heating system: less losses in the heating grid, smaller boiler for a maximum of full load operating hours. All: Shorter pay-back period (lower initial costs, higher efficiency and expected lower operational costs.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Exploring the Effects of Emotion on Human Cognition'.

assistant: **Objectives**

Emotions evoke a profound modulation of human cognition. Emotional events are susceptible to preferential perceptual processing and are more likely to be remembered than neutral ones. But how does the emotionality of a stimulus lead to enhanced perception and memory? The series of experiments proposed will investigate the underlying human neurobiological mechanisms by which emotion modulates these two cognitive processes. This will proceed through the integration of basic psychological tasks, human psychopharmacology and an examination of functional neuronal measures in humans, employing intracranial EEG recordings from patients with depth electrodes, magnetoencephalography (MEG) and functional magnetic resonance imaging (fMRI). The core hypothesis is that emotions evoke an amygdala-dependent modulation of other brain areas; higher-order visual cortex and hippocampus for effects on perception and memory, respectively. A central theme is that the noradrenergic (NA) system is critical for this interplay between different brain areas. Emotions can also evoke deleterious effects on memory, particularly for stimuli that precede the emotional event, but the mechanisms underlying this are also poorly understood. Initial experiments presented here will characterise the temporal profile of this retrograde amnesia, as well as the neurophysiological and biochemical correlates. The next study, to be performed in the context of simultaneous EEG-fMRI recordings, tests whether response inhibition-induced associative memory impairment has a NA basis. A final study examines how the spatial frequency of emotional stimuli modulates both perceptual and memory-related neuronal activity in healthy controls and patients with depression, a condition characterised by abnormal emotional processi