RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Search Computing' to be submitted under Seventh Framework.

assistant: **Abstract**

Who are the strongest European competitors on software ideas? Who is the best doctor to cure insomnia in a nearby hospital? Where can I attend an interesting conference in my field close to a sunny beach?  This information is available on the Web, but no software system can accept such queries nor compute the answer. We hereby propose search computing as the new multi-disciplinary science which will provide the abstractions, foundations, methods, and tools required to answer these and many similar questions. The emerging paradigm of service computing has so far been neutral to the presence of search services, which are equal ""inter pares"". This proposal brings about a simple yet revolutionary idea: service computing evolves into search computing, a new paradigm where ranking is the dominant factor for composing services. While state-of-art search systems answer generic or domain-specific queries, search computing enables answering questions via a constellation of dynamically selected, cooperating search services. The idea is simple, yet pervasive. New foundational theories are needed, rooted into formal disciplines such as mathematics, statistics, and optimization theory. New language and description paradigms are required for expressing queries and for discovering services. New interfaces and protocols help capturing ranking preferences and enabling their refinement. Semantic domain knowledge helps enriching terminological knowledge about objects being searched. Ranking is always relative to individuals and context, thus the study of personal and social behaviour is also essential. Economical and legal implications of search computing must be understood and mastered. In summary, search computing is a multi-disciplinary effort which requires adding to sound software p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Dynamic and distributed adaptation of scalable multimedia content in a context-aware environment' in the context of a Sixth Framework call.

assistant: **Objectives**

DANAE proposes to address the dynamic and distributed adaptation of scalable multimedia content in a context-aware environment. Its objectives are to specify, develop, integrate and validate in a testbed a complete framework able to provide end-to-end quality of (multimedia) service at a minimal cost to the end-user. An application will be specifically developed and implemented on a demonstrator, to illustrate the new service concepts pioneered by the Project.The work will cover:(i) the definition of scalable media formats with their associated meta-data,(ii) their adaptation to the session context for making full featured distributed multimedia scene adaptation through global optimisation of audio, video, 2D graphics, 2D/3D virtual characters and(iii) the transport and delivery of multimedia content to the end-user. Error resilient and efficient (in terms of bitrate and required processing power in the player) coding schemes will be studied to cater for the specific constraints introduced by the existing multiplicity of networks and terminals.The inter-relationship of content adaptation and scalability with Digital Rights Management (DRM) and charging issues will also be explored. As an outcome, an advanced MPEG-21 chain will be produced. Finally potential new business models will be analysed that would allow assessment of the commercial viability of the new services pioneered by DANAE. DANAE is proposed for a duration of 30 months. After specification and development, all individual key building-blocks implementing the novel concepts and technical features will be integrated, and technically validated in a central end-to-end test-bed which will then be used to demonstrate the novel service types with the developed application.DANAE work will be based on the existing M
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Ca 2+binding proteins' (1998-2002).

assistant: **Concept**

The Sixth European Symposium on Calcium Binding proteins will be held in Paris 14-18 June 2000. It will be the 6th symposium of a series of European Symposia on Calcium Binding Proteins in Normal and Transformed Cells that are held every second year in different European cities. In line with the previous symposia in this series, the Paris meeting aims at encouraging exchanges and discussions in various areas of the role of calcium in cell biology and diseases. Topics expected to be covered range from calcium sensing and signalling to molecular aspects of calcium-regulated events and the characteristics of different calcium binding proteins. Among the latter, C2-domain proteins, annexins, EF-hand proteins, extra-cellular proteins will be covered with respect to their structure and function. Structural information obtained by different techniques will be presented. The functional approaches, including the generation of dominant negative mutants as well as gene knockouts both at the cellular level and in mice are gaining momentum. A large number of communications will address the use of new technologies localising in real time calcium-binding proteins in relation to calcium levels by the use of new probes, new optical & electronic devices. Finally, in addition to covering aspects of basic research, new results establishing correlation between proteins involved in calcium-stimulus response coupling and human diseases will be presented.The meeting will be attended by around 150 to 200 persons. It will be a forum for discussing novel scientific results both during the talks & in the poster sessions. An important participation of companies developing new devices & new soft wares is in discussion. They will present material and will offer workshops in the afternoon. A large num
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'NUclear COmponents Based on Additive Manufacturing' (NUCOBAM) targeting Horizon 2020.

assistant: **Abstract**

NUCOBAM aims at developing the qualification process and provide the evaluation of the in-service behaviour allowing the use of additively manufactured components in nuclear installation. Additive Manufacturing (AM) will allow nuclear industry (i) to tackle component obsolescence challenges and (ii) to manufacture and operate new components with optimised design in order to increase reactor efficiency and safety. NUCOBAM will conduct the required studies to implement AM process in nuclear design codes and standards to produce components for nuclear power generation equipment. The project will be based on two coupled strategies. The first part will consist of a collection of the physical, mechanical and microstructural characterization of the materials that result from AM process in order to establish a qualification and codification process. The second part will be dedicated to the evaluation of AM material behaviour in service, especially regarding main degradation mechanisms that occur in LWR (thermal ageing, irradiation…). Materials will be manufactured and some of them will be submitted to post-treatment (heat treatment or high isostatic pressure). The results will be analysed and compared with existing approved manufacturing processes by design codes. This work will lead to evaluate and deduce the main parameters required for specification. NUCOBAM will gather leading edge organisations able to pull the complementary expertise and capabilities mandatory to demonstrate the use of AM components in a nuclear installation. The consortium will thus involve electricity utilities, operating nuclear assets, component manufacturers, design owners, public service experts in nuclear and radiation risks as well as research and competence centres involved in mechanical assessme
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Quasistatic evolution problems for material failure due to fatigue'.

assistant: **Objectives**

This research project deals with evolutionary problems arising in the modelling of material failure caused by fatigue. In Materials Science, fatigue is the process by which a solid exhibits a loss of its elastic properties as a consequence of repeated cycles of loading and unloading, and it is responsible for the majority of unforeseen structural failures. Infamous accidents have shown how the consequences of fatigue can be catastrophic, causing tremendous financial losses, serious injuries, and deaths.In contrast to the active Engineering research on the topic, fatigue phenomena have been so far scarcely investigated by mathematicians. Since Mathematical Analysis has played a crucial role for the proof of consistency of variational models in Fracture Mechanics, it is clear that this field would benefit from a cogent and cutting-edge mathematical theory of fatigue.The aim of FatiguEvoPro is to prove the existence of evolutions for mechanical models of material fatigue. The existence of quasistatic evolutions for Rate-Independent Systems featuring fatigue will be investigated within damage, brittle fracture, and cohesive fracture.The models of FatiguEvoPro describe the current state of the mechanical system in terms of a memory variable which takes into account the whole history of its evolution. The resulting weak control of this variable is the main source of difficulty in the proof of existence of evolutions. The new effective techniques developed to solve this problem have great potential for applications in different contexts.The achievements of FatiguEvoPro will develop a new branch of the variational modelling of Fracture Mechanics and will strengthen the mutual interest between mathematicians and engineers on a topic of utmost importance. The planned training act
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'IRIS Feasibility Study – Phase 1' (IRIS-1).

assistant: **Innovation**

The IRIS Feasibility Study – Phase 1 (IRIS-1) Project aims to assess the overall feasibility of the introduction of the Intensive-care Risk prediction and Identification System (IRIS), an innovative real-time patient monitoring and personalised risk prediction and identification system, into the healthcare sector. Thousands of surgery patients in Europe and worldwide die each year due to complications during the post- operative period and thousands more survive with disabilities, making the economic burden of post-operative complications in surgery patients amount to hundreds of millions of euros annually. It is widely accepted that early recognition of complications can reduce their severity and consequences: continuous patient monitoring systems and risk scoring systems are available but they lack suitability for patients in intensive care, trust calculations at time intervals, analyse solely a fraction of available patient data, cannot detect multi-dimensional trends, rely on arbitrary thresholds to generate alarms and cannot be customised for each patient. Thus, there are increased mortality rates and re-admission rates to hospital, contributing to the overwhelming financial and economic burden of public healthcare.Addressing serious morbidities, such as heart, renal and respiratory failures, and capable of surpassing human limitations in processing large volumes of patient data, IRIS is a real-time adaptive and dynamic patient monitoring and risk prediction and identification system, sensitive to variable interactions and capable of incorporating patient data to identify trends in individual patients’ physiological parameters that predict post- operative complications. Developed by RINICARE, IRIS will assist clinical staff to identify at an early stage serious comp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Double-site ligands for the inhibition of Cholera toxin' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Specific binding between bacterial enterotoxins and oligosaccharides on the host cell membrane is a paradigm for protein-sugar interaction. One of the best characterized recognition pairs is formed by ganglioside GM1 and the cholera toxin (CT).  Recently, Krengel´s group has identified a second binding site, which appears to be present in the close CT congener LT and in CT from the El Tor strain, responsible for the current cholera pandemic. This binding site, which is clearly distinct from the primary GM1 binding site, recognizes blood group ABO antigens, fucosylated carbohydrate structures carried on both glycolipids and glycoproteins. The main objective of our project is to develop new dual-site ligands for cholera toxin inhibition featuring 2 pharmacophoric fragments, a GM1 mimic and a blood group mimic, connected across a linker able to span the two binding sites of enterotoxins. The GM1 binding site will be targeted using a functionalized GM1 mimic recently developed in the host laboratory which binds to CT and allows conjugation to aglycons. The blood group binding site will be targeted by selecting the mimimal blood group epitope using STD NMR experiments. Linkers of different lengths will be built in modular fashion by connecting PEG monoamine fragments using squaric acid connectors. Optimal linker length will be selected by combinatorial target-guided dynamic synthesis of a disulfide library in the presence of hLTB or CTB/hLTB toxin hybrids as templates. The required proteins will be obtained through a collaboration with the Krengel group. This project is connected to the activities of the  COST D34/001/05 WG, working on cholera toxin inhibition and sensing.  This fellowship and the framework provided by the COST group will ensure the opportunity for the propo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Dissipative Self-Assembly: A powerful but unexplored tool to create temporary supramolecular hydrogels' to be submitted under Horizon 2020.

assistant: **Abstract**

The aim of this study is to develop molecular temporary hydrogels coupled to an energy dissipating chemical reaction (DisMolGels). Until now, most molecular self-assembled materials operate close to thermodynamic equilibrium, under static conditions, and are thus far from the interesting features biological living “materials” display. Biological materials are thermodynamically open and are kept far from equilibrium by a constant input of energy. This mode of self-assembly, one of the requirements of life, is referred to as dissipative or dynamic self-assembly. For this project I will focus on the recreation of part of such dissipative processes, and translating them to our current static hydrogel materials. With that, dynamic hydrogels with entirely new properties, most prominently their tunable lifetime and stiffness, will be developed. To do so, chemical fuels will be used as energy input and simple synthetic peptide derivatives will be constitute the self-assembling building blocks.  Not only will this project result in hydrogels with a tunable lifetime and stiffness, it also aims at setting new design guidelines and requirements to develop dynamic systems. Thereby it aims at aiding the scientific community as such rules currently lack, hampering the development of these interesting systems.The ambitious research project builds on what I have already accomplished working on thermodynamically static self-assembled systems and the expertise that the host group offers in terms of dynamic materials approach. The research experience I will gain and all training received during the MSCA, will reinforce my expertise in this field and empower me to grow as an independent research leader.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a FP7 proposal for the project 'A dedicated network of incubators detecting new FP7 opportunities for SMEs through connecting existing regional clusters in biotech, renewable energies and IST'.

assistant: **Objectives**

DETECT-it 2 aims to ensure, that the EC Business Innovation Centre (BIC) network of industrial incubators and their regional client base of SMEs are fully prepared to take full advantage of the first calls of FP7. In order to achieve this objective, DETECT-it 2 will build on ETI call) in which a network of 30 BICs across Europe was mobilized. Since the kick-off of this project, nearly 1000 SMEs have completed a detailed audit specifying their sectors of interest and their R&D skills and competencies.DETECT-it 2 aims to take full advantage of the operational systems and SME database developed in DETECT-it 1 to introduce a new work programme. This new programme will be substantially different in that it is geared from the outset towards preparation for the first calls of FP7. In addition to the IST and renewable energy sector, biotechnology for health will be targeted as a priority area in response to the needs of the BIC SME client base. Over half of the consortium will be made up of new partners who will inject fresh ideas and new skills into DETECT-it 2. Over 600 new SMEs will be targeted to participate. These SMEs will be encouraged to develop 300+ ideas for new research projects and to submit 1000+ expressions of interest.The focus of resources will be placed firmly on the bottom up approach of developing SME intensive" FP7 projects through connecting regional clusters. At all stages of DETECT-it 2, the direction and success of the project will be achieved through advice and guidance from a specialist and highly experienced panel of NCPs and FP6/FP7 experts. A core team of the best performing partners from DETECT-it 1 will participate to transfer knowledge and skills learned from the past. EBN plays an active role in networking clusters with academic, investor and co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Innovative practices, tools and products to boost soil fertility and peat substitution in horticultural crops' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The main objective of SPIN-FERT is to integrate optimised and validated innovations in soil management practices and improve peat-free substrates to enhance soil health in vegetable, fruit and ornamental crops. SPIN-FERT will exploit outcomes, including patents, from several related projects, in particular EXCALIBUR as 6 of its members are partners in SPIN-FERT. Multi-actor approach is at the core of SPIN-FERT methodology and consortium for extensive knowledge transfer and co-design. Specifically, SPIN-FERT will optimize the production process of chosen fertilising products and improve their formulation with innovative protocols to increase efficacy. SPIN-FERT will leverage agro-food by-products into resources for agricultural production, exploiting them further into peat-free substrates. These and reconditioned coir will be formulated with specifically selected microbial strains to improve their characteristics and applicability, particularly for nursery industry. All innovative products will be validated in field trials in 4 regions in Europe (PL, I, F and UK). Five tools will be delivered to support the correct implementation of the practices, to facilitate products registration and favoring policy development, including a Soil Holistic Quality Index. SPIN-FERT will carry out economic, social and environmental assessments of the peat-free substrates and soil management innovations, to demonstrate sustainability. All this information will serve to develop a comprehensive policy framework for measures fostering wide adoption of soil-friendly practices. To further ensure commercial relevance of the peat-free substrates and soil management innovations, SMEs, public authorities and citizen representatives partner or advise on SPIN-FERT for effective project delivery and m