RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Blazed concave diffraction gratings of high numerical aperture' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Research objectives and content To investigate whether it is possible to use holographic optical components to increase the numerical aperture for which it is possible to make blazed concave diffraction gratings. The steps involved are: l . Record an holographic condensing mirror by passing one wavefront through the inclined concave substrate. 2. Set up a standing wave interferometer incorporating the holographic component. 3. Determine the maximum numerical aperture that can be achieved 4. Make a series of gratings with different spatial frequencies 5. Measure the performance of the gratings as a function of wavelength in various grating mountings. 6. Assess the advantages and shortfalls of the method for scientific and commercial spectrometers 7. Attempt to replicate gratings on the edges of planar optical wavegindes 8.Manufacture Manufacture planar waveguide spectrometer. Training content (objective, benefit and expected impact) The research will serve to transfer the technology for the manufacture of gratings to the university and so extend their existing expertise. It will also acquaint them with some genuine industrial needs and provide a useful contact with an industrial user. Links with industry / industrial relevance (22) The research is a highly relevant extension of 'holographic' grating technology developed by the applicant and used by Pye Unicam for twenty years. The company will provide consultancy on design, measurement and assessment of the results and guidance for further research. The research also extends naturally into the university's existing work on planar waveguide sensors and multiplexers which is itself of great relevance to industry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Consequences of warming-driven vegetation change for Arctic carbon cycling and feedbacks to the global climate system' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

ArcticEDGE will identify the consequences of warming-driven vegetation change for the functioning of Arctic ecosystems, particularly the cycling of carbon, and the impact on the global climate. The Arctic is the fastest-warming region on Earth, and Arctic soils contain more than double the amount of carbon currently in the atmosphere. Changes in the vegetation can influence whether this carbon is released into the atmosphere, thus contributing to additional climate warming, or stored in soils and plant biomass. Until now, we have lacked the ability to scale up from site-specific, local-scale studies to generalizable vegetation-function relationships relevant for the entire Arctic. ArcticEDGE will: 1) quantify the relationships between widely-measured plant functional and phenological traits and three key ecosystem processes related to global carbon cycling: litter decomposition, primary production, and fire dynamics, using field and laboratory experiments, 2) predict the rate with which these traits are likely to change in response to warming by identifying the relative contribution of turnover in species identity, shifts in abundance, phenotypic plasticity and genetic differentiation to trait variability and change over time, 3) determine the contribution of Arctic vegetation change to global-scale vegetation-climate feedbacks by combining knowledge from aims 1 and 2 with multi-decadal records of vegetation change and responses to experimental warming and precipitation at hundreds of locations across the Arctic, and 4) produce quantifiable outputs that will feed directly into Dynamic Global Vegetation and Earth System models to determine the consequences of Arctic vegetation change for the global climate. The knowledge generated by ArcticEDGE will contribute both to ou
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Conservative iron chelation as a disease-modifying strategy in Parkinson’s disease: a multicentric, parallel-group, placebo-controlled, randomized clinical trial of deferiprone' (FAIR-PARK-II).

assistant: **Innovation**

Parkinson’s disease (PD) is a major, chronic, non-communicable disease and the 2nd most frequent neurodegenerative disorder worldwide. Excess iron is primarily detected in the substantia nigra pars compacta, where dopaminergic neurons are exposed to high levels of oxidative stress produced by mitochondrial disorders and dopamine metabolism. Our previous preclinical, translational and pilot clinical studies demonstrated that novel iron chelation therapy with the prototypic drug deferiprone (DFP) (i) induces neuroprotection in cell models of PD via a powerful antioxidant effect, (ii) reduces regional siderosis of the brain, (iii) reduces motor handicap via inhibition of catechol-o-methyl transferase, and (iv) slows the progression of motor handicap in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model and in early PD patients. This project now seeks to demonstrate that conservative iron chelation therapy with moderate-dose DFP (30 mg/kg/day) slows the progression of handicap in de novo PD patients while not affecting systemic parameters. The 9-month, parallel-group, randomized, placebo-controlled, multicentre trial will be followed by a 1-month wash-out period. The primary efficacy criterion will be the change in motor and non-motor handicap scores on the Total Movement Disorders Society Unified Parkinson’s Disease Rating Scale to identify disease-modifying and symptomatic effects. The secondary efficacy criterion will be the change in score between baseline and 40 weeks (i.e. probing the disease-modifying effect only). Potential surrogate radiological and biological biomarkers, health economics and societal impacts will be assessed. 17 national, European and international research and innovation activities will be linked with the project. The study results shou
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'High dense smart power capacitor', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Due to reduction of losses and optimization in aircraft designs, aircrafts are on being more electrical. This perspective takes place in an environmental respect context. One main goal of CleanSky project is to improve Systems for Green Operations (SOG). Management of Aircraft Energy (MAE) is one of the most important challenges. HDSPC project takes place in this context.In this kind of specific products, EUROFARAD heritage in plastic film capacitors is fundamental. Moreover, a good comprehension in customer requirements (mechanical, electrical, thermal …etc.) is essential for the actual demand but also to understand problematic for future design. Management of aircraft energy leads EUROFARAD to focus on the same goals than our customers:-Higher working temperatures-Higher energy density (also means weight reduction)-Possibility for sensing capacitors for self-diagnostics (lifetime and  control)During HDSPC project, our main goals will be to improve our technology in term of working temperature and miniaturization. A special attention will be paid on material analyses and choices: both plastics polymers for capacitors but also capacitor covering materials in aeronautics environment. Moreover, R&T will be done on SMART capacitor, with the main goal of providing physically integrated (into the capacitor) solution for sensing “state of the capacitor” under electrical control signals.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Cloud-based Visibility Service for Software Defined Networks' (SDN-Polygraph), addressing dissemination and exploitation.

assistant: **Impact**

Today, enterprises depend on the Internet and computer networks. Costs associated to network malfunctions are huge, estimated around 30K€/hour; companies average 175 hours of downtime per year, which yields losses above 5 M€/year per company. To avoid these huge costs, network administrators require network visibility: the ability to understand what happens in a network. Thus, companies are investing in visibility tools; the market of Network Performance Monitoring (NPM) is currently estimated at $2.4Bn, growing at >11% yearly.However, enterprises today are still not investing as much as they should in network visibility, because of (1) deployment complexity, which requires expert technicians and planned interventions, and (2) high upfront costs of both hardware and software-based solutions.A revolution in the networking world called SDN is currently undergoing. This new technology allows software components to alter the network, which becomes almost “programmable”. This opens a window of opportunity to create a SDN visibility product that removes both barriers: it can be deployed with one click, offered cheaply from the cloud at scale, and billed on a subscription basis. The market of SDN is currently $3.5Bn and will grow 10x until 2018. We believe that by combining SDN and network visibility we can at least double the market of our segment, increasing it by $2.4Bn.The objective of this project is to refine our current Business Plan and reduce the uncertainties in the project. By reducing risk, we will consolidate it and open it to further investment. In particular, we will seek an early adopter and refine the value proposition of our first version of the product.We are a company that commercializes network visibility solutions; our product (unrelated to SDN) is curren
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'The right to work for men and women with disabilities - successful collaboration between employers and support systems using the workplace as an arena for work inclusion'.

assistant: **Concept**

The employment rate of persons with disabilities across Europe is much lower than of the general population and thedisability employment gap has remained considerable, independently of labour market policies. Over time differentapproaches to work inclusion of persons with disabilities have been developed, where support-side approaches, especiallysupported employment methods, that are using the workplaces as instruments of inclusion, have been shown effective. Thecollaboration between employer and the support system is crucial when using the workplace as an arena for work inclusion,but there is a lack of research on employer-support system relations and how they can be formed to facilitate increased employment of  persons with disabilities.Using theoretical frameworks from the field of sociology and psychology, and by drawing conclusions from qualitative data, this project addresses successful collaboration between employers and support systems in work inclusion of men and women with disabilities. Results from observation/interview studies in Norway and Sweden and insights from a literature review will inform support-side approaches and facilitate work inclusion. During the fellowship will benefit from the expertise of the INTEGRATE core research group, at OsloMet - Oslo Metropolitan University and its international expert network and from short visits to other European excellence research centers in work inclusion. Building on my previous work and skills in labour market and disability research, the project activities will lead to further development of my professional maturity as a researcher, while the results will have a key impact on the development of effective support-side methods and as called for in EU policies, on the labour market participation of persons with
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Language-Processing by Overlapping Predictions: A Predictive Coding Approach'.

assistant: **Concept**

This project aims at elucidating fundamental neural computations underlying language processing. While we have gained enormous insights into the localization of language in the brain and the temporal sequence of language processes (e.g., syntactic vs. semantic), we know very little about the actual computations underlying language processing. I propose that the framework of predictive coding can fill this gap. Predictive coding is a fundamental theory of sensory processing in the brain that has recently gained enormous attention in psychology and neuroscience. While models of language assume a bottom-up driven processing stream from sensory areas through different linguistic processing stages (e.g., phonetic, syntactic) towards semantic interpretation, predictive coding postulates that high-level brain systems actively construct models of the external world and pass resulting predictions about upcoming events to lower sensory systems. Only if predictions are violated, a prediction error is signalled in a bottom-up fashion to higher areas where internal models are adjusted to minimize prediction error. Here, I postulate that language-processing is the result of multiple overlapping predictions from different sources of linguistic information, if available. I propose a research program that (a) explores the presence of neurophysiological markers of predictive coding during language processing, (b) tests quantitative hypotheses from predictive coding concerning strength and precision of prediction error signals, for established language effects, and (c) explores the domain generality of identified mechanisms. To this end, established electrophysiological and brain activation markers of sentence processing will be combined with advanced model-based data analysis tools. Fina
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Exploring the Relationship between Climate, Environment, and Health in Antiquity through the Papyri from Hellenistic, Roman, and Byzantine Egypt' to be submitted under Horizon Europe.

assistant: **Abstract**

RECLEAN aims to study the impact of human activities on the environment of Hellenistic, Roman and Byzantine Egypt (ca. III c. BCE - VII c. CE), the effects of climate variability and pollution on the health of the inhabitants of Egypt, and the people’s degree of awareness of environmental issues and their consequences on health. Research will focus on a body of sources that have not yet been comprehensively analysed, the papyri from Egypt written in Greek and Latin, which will be integrated with literary and historical sources, archaeological finds and inscriptions, and with the results of studies based on palaeoclimate proxies and palaeopathological samples. The outgoing phase of RECLEAN (years 1 and 2) will take place at the Departement Altertumswissenschaften of the University of Basel, which hosts the Basel Climate Change and Ancient History Lab, an interdisciplinary initiative dedicated to the study of ancient environmental issues: here the fellow will receive specific training in Environmental History of Antiquity, essential for the pursuit of the project’s objectives, in a vibrant and multidisciplinary environment that brings together specialists in the Humanities and in the Environmental Sciences. The return phase (year 3) will take place at the Dipartimento di studi umanistici e del patrimonio culturale of the University of Udine, where the fellow will consolidate her preparation in Papyrology and further delve into the subject of “environmental awareness” in Antiquity. The results of RECLEAN will be made available to the scientific community through open access publications and presentations at conferences, while the communication activities will reach a wider audience with the aim of stimulating a reflection and debate on environmental issues in a historical
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Directed Evolution of Enzyme for Applied Biocatalysis at Ultrahigh Throughput in Picoliter Droplets'.

assistant: **Objectives**

Enzymes have established as a new class of catalysts in the field of modern synthetic chemistry and continue to gain in importance. Directed evolution is currently one of the most promising approaches aiming at enzymes with desired catalytic activities and it's potentially directly correlates with the library size that can be screened. One of the most powerful approaches to overcome these limitations is arguable the recently introduced microfluidic droplet technology; this methodology not only allows to quickly screen millions of clones in a cost effective manner, but is also broadly applicable since fluorometric as well as colorimetric assays can be used. Interestingly, even though numerous publication highlight its potential, an unambiguous evidence of its ability to provide synthetically relevant biocatalysts still needs to be furnished. In addition, access to this technology is currently limited to a few academic research groups and thus, this approach requires further implementation to evolve as an easily manageable lab routine in the near future. This project is designed to unite three competencies: i) the expertise of the Hollfelder Group in regarding micro-engineering and protein engineering in droplets, ii) the empirical knowledge of (bio)chemists at Johnson Matthey in view of economically successful industrial applications of biocatalysts and iii) the strong track record of the experienced researched to successfully solve problems at the biology/chemistry-interface. The objective of the project is to perform a proof-of-principle study by improving a well-known alcohol dehydrogenase for the selective desymmetrization of a meso-diol, thereby giving access to a synthetically sophisticated alcohol. In addition, the final aim is not only to obtain an improved mutan
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Power effects aerodynamics for a regional turboprop'.

assistant: **Objectives**

A CFD characterisation of a regional turboprop configuration with particular focus on the Reynolds number dependence of the power effects, both direct (1P forces and moments) and indirect (slipstream) is performed, in concert with a wind-tunnel test in a pressurised facility to allow variation in Reynolds number. The turboprop is furnished with new control surface concepts. Variable Fidelity Modelling (VFM) techniques are used for the CFD characterisation, deploying steady RANS with actuator disk modelling as the low-fidelity approach and unsteady RANS with full propeller blade modelling as the high-fidelity approach. The latter uses a novel coupling between the RANS solver and a Vortex Particle Method to increase the accuracy of slipstream effects without resorting to costly mesh refinement in the propeller wake. A methodology for determining reliable performance data at full scale is developed, using a combination of CFD and wind-tunnel data at atmospheric conditions only, again deploying VFM.