RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Advanced Leidenfrost Effect' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

When a liquid droplet is placed on a solid surface with a temperature significantly higher than the boiling point of the liquid, the droplet hovers above the surface on a thin layer of its own vapor, a phenomenon known as the Leidenfrost effect. While this effect is highly undesirable in certain cooling applications due to the reduced energy transfer between the solid and evaporating liquid caused by the poor heat conductivity of the vapor, it can be of significant interest in various processes where avoiding contact with the surface is advantageous.The LeidenForce project aims to comprehensively study the Leidenfrost effect and propose novel applications, either to mitigate its adverse effects or leverage its advantages. LeidenForce intends to (i) shift the fundamental understanding of the transition to the Leidenfrost state, (ii) optimize the heat transfer between the droplet and the substrate, (iii) utilize the isolated droplet to manipulate small amounts of liquid in unconventional scenarios (e.g., on a liquid surface, within a channel), and (iv) harness the vapor film to capture or confine particles using an external electrical field.The practical implications will be leveraged by non-academic institutions involved in aviation (such as AIRBUS), metallurgy (CRM), cryogenics (Air Liquide), and space exploration (Centre Spatial de Liège). In aviation, managing cryogenic fuel is a crucial step toward achieving zero-emission flights. In metallurgy, innovative cooling methods will be developed based on mitigating the Leidenfrost effect. Air Liquide will address cooling issues by introducing particles into the evaporating liquid to modify the Leidenfrost effect. Lastly, at the Centre Spatial de Liège, Leidenfrost droplets will be utilised to delicately clean surfaces by t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Integrated process unit control and plantwide optimisation' in the context of a Fifth Framework call.

assistant: **Objectives**

Process industry has become more market driven. An increasing number of product grades have to be produced within tight specifications and against competitive prices using an increasing variation in input quality of feedstock material. Difficulties of production units to adapt to this demand lead to unnecessary resource usage, waste production and energy usage. INCOOP is an RTD project aiming at strongly increasing flexibility (e.g. fast and cost effective changeovers) and efficiency (towards the physical and chemical optima) of process plants. This will be done by setting the first important steps towards the control and optimisation technology of the future. RTD on two industrial benchmark processes (models) should lead to guiding principles for the systematic development of hybrid models and techniques to reduce the complexity of hybrid models in order to derive approximate models suitable for non-linear controllers and dynamic optimisers. Further RTD work will be done to develop dynamic optimisation algorithms, non-linear MPC and data-reconciliation techniques.1. Prototype software tools that support or perform the aforementioned tasks. 2. Demonstration of the techniques:- Simulations of industrial processes;-First field test applications to real production processes at end-user sites.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Sustained Release Ocular Bevacizumab for the treatment of wet acute macular degeneration' (STROBE) targeting Horizon 2020.

assistant: **Abstract**

Sustained Release Ocular Bevacizumab for the treatment of wet acute macular degenerationThis feasibility study is to verify the technical and economic viability of a sustained release bevacizumab product (SR Bevacizumab) to improve the safety, cost-effectiveness and patient acceptability for the treatment of wet age-related macular degeneration (AMD). AMD is the leading cause of blindness in those aged over 50 and causes blurring, distortion and loss of central vision and almost always affects quality of life.  Prototype SR Bevacizumab products will be manufactured using CriticalMix, an advanced manufacturing and processing technology developed by Critical Pharmaceuticals, which will encapsulate bevacizumab in biodegradable polymers suitable for sustained release of the drug in the eye.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Digital Glossary of Nuzi Hurrian' in the context of a Horizon Europe call.

assistant: **Objectives**

After centuries of research, scholars have deciphered most ancient Mesopotamian languages, but a few are still not fully understood. One of these last frontiers is Hurrian. The biggest problem for researchers today is that the meaning of many words is still unknown. The texts from Nuzi (c. 15th-14th BC, modern Yorghan Tepe, in Iraq) are key for the decipherment of Hurrian. They were written in a context of diglossia: by people who spoke Hurrian but wrote in Akkadian, and, as is usual in such contexts, Nuzian scribes used Hurrian loanwords. Although the Nuzi corpus is the largest of its kind, a systematic study of Nuzi Hurrian has never been undertaken.DiGloss aims to make a significant contribution to the comprehension of the Hurrian lexicon and bring the knowledge of this language to the next level. To achieve this goal, all Hurrian words in Nuzi texts will be compiled in an online database. I will apply an interdisciplinary methodology that combines contextual and morphological analysis to (1) understand how the scribes adapted the cuneiform writing system to record Hurrian and (2) determine the meaning of specific lexical items. The project will be based at Paris 1 University and will be supervised by Prof. Brigitte Lion, a world-leading expert in the study of Nuzi. Her expertise and the multidisciplinary environment at the host institution provide the ideal context for the development of DiGloss.The project will produce indispensable tools for future research in Hurrian, thus boosting my academic career. Clarification of the Nuzi Hurrian lexicon will bring us closer to the complete decipherment of Hurrian, and will allow scholars to fully understand texts that are only partially comprehensible today. As written texts are the cornerstone of the study of ancient histo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Stomatocyte Nanomotors: Programmed Supramolecular Architectures for Autonomous Movement'.

assistant: **Objectives**

The main goal of this ERC proposal is to harness a completely new approach to constructing biocompatible nanomotors, using supramolecular assembly of amphiphilic block-copolymers for loading the engine and catalysis as the driving force for autonomous movement. Polymersomes assembled from amphiphilic block copolymers can be further re-engineered to perform a controlled shape transformation from a thermodynamically stable spherical morphology to a kinetically trapped stomatocyte structure with controlled opening. These stable structures can selectively entrap catalytically active nanoparticles within their nanocavity making their design ideal for nanoreactor applications. The decomposition of hydrogen peroxide by an entrapped catalyst has been shown to generate a rapid discharge of gases and consequently generate thrust and directional movement. The design of the loaded stomatocytes is a truly miniature monopropellant rocket engine in which the catalytically active nanoparticles are the motor, the hydrogen peroxide is the propellant and the controlled opening of the stomatocyte is the nozzle. Their unique shape allows for added capabilities, extra compartmentalization for loading efficiency, polymeric PEG surface for biocompatibility and entrapped particles for catalytic activity. The supramolecular approach to assembling the motor allows facile alteration of its constituent parts: motor, fuel and cargo to make it more suitable for biological applications (type of catalytic particles, surface modification for cellular uptake or suitable biofuels). The appropriate design of the motor with recognition sites on the surface can facilitate the recognition, isolation and transport of specific type of cells, or can navigate the payloads within the cell via chemotaxis. Besides t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Multicentre discovery of breast cancer biomarkers' (CANOMICS) under Seventh Framework.

assistant: **Objectives**

Breast cancer is the most common cause of death from cancer among European women, and over half of the worldwide breast cancer related mortalities occur in the developing world. Despite improvements in surgical techniques and chemoradiotherapy, the ability to cure patients with breast cancer remains limited and five year survival for patients with advanced disease is dismal. Expression profiling and biomarker discovery aims to provide means for tumour diagnosis, classification, and prediction of response to therapy and prognosis. This could potentially lead to the building of robust early detection modules, and personalised effective breast cancer therapies which would improve outcomes. The emerging field of proteomics targets the discovery of early stage biomarkers in biological tissue which could lead to new clinically valid biomarkers discovery.The goal of this application is to develop proteomic tests using different approaches for identification of breast cancer biomarkers which could ultimately form the basis of a screening and/or prognostication test. Using different biological samples and proteomic biomarkers’ discovery methods improves the prospects of classification and stratification of different biological groups. Early cancer detection, improved treatment selection and outcome are expected in return. This project is focused on early detection where comparative analysis of proteomes of normal individuals and patients with cancer, as well as different subgroups of patients, will be used to develop a “signature” of changes that are characteristic of breast cancer. Our study will be based on serum and breast tissue samples collected and analysed in 5 centres.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Eucon eac ii' under Fifth Framework.

assistant: **Concept**

The quality of our environment is one of the highest values in our modern society and deserves special consideration and protection. It is threatened by human activities in various respects: through industrial mass production and the resulting release of man-made chemicals into the environment, through the application of pesticides that leak into drinking water resources, through increasing traffic that causes significant air pollution or through the accidental spill of chemicals, to name just a few. In all cases, the quality of life and of our environment, or even human life or natural vegetation and wildlife may be at danger, and in all these cases, Environmental Analytical Chemistry is required to diagnose the status of the environment, and to decide whether there is a potential hazard.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'New isotope tracers for core formation in terrestrial planets' under Seventh Framework.

assistant: **Concept**

This proposal aims to develop new isotopic tools designed to constrain the core formation process in the Earth. We will use isotopic fractionations imparted by metal-silicate equilibration during core formation to obtain new and firm constraints on (i) the physical and chemical processes during formation of the Earth's core; and (ii) on the origin of volatile elements and the volatile accretion history of the Earth. The underlying concept of our  approach is to compare observed mantle-core isotopic fractionations (determined on natural samples) to the experimentally-determined isotope fractionation between liquid metal (core analogue) and liquid silicate (mantle analogue). Since the magnitude of isotope fractionation is strongly temperature-dependent, this comparison will enable us to evaluate core formation temperatures. I propose to use the stable isotope systematics of W, Mo and Cr to assess as to whether core formation temperatures for the Earth, Moon, Mars and asteroids are different, as would be expected if metal segregation in the Earth involved metal-silicate equilibration in a deep magma ocean. If instead all bodies have similar core formation temperatures, then formation of the Earth's core most probably involved some disequilibrium induced by direct core mergers during accretion from differentiated bodies. The second major theme of the proposed research uses Ge and Sb stable isotopes to trace the origins of Earth's volatiles. The combined investigation of Ge and Sb isotope fractionations in natural samples and metal-silicate equilibration experiments will enable us to determine as to whether Ge and Sb, and with them other volatile elements, show an isotope signature resulting from core formation. Identifying such a signature would provide the unequivocal evid
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Heart On chip based on induced pluripotent Stem cell Technology for personalized Medicine' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Many rare diseases cause chronic health problems or are even life-threatening. The impact on the quality of life of affected patients, of whom many are children, is significant.  To date, a limited but increasing number of so-called orphan drugs (drugs for rare diseases) are reaching patients. However, the majority of rare diseases are still without any effective treatment. The development of novel human systems for drug discovery  therefore represents a major public health priority. Microfluidic technology-based “Organs-on-a-chip” represents a powerful tool for investigating rare disease mechanisms and testing new drug and treatment due to their ability to mimic tailored micro-environment architecture inspired by organ-level functions in vivo. However, due to the variability in rare disease mechanisms from one patient to another, organ on chip technology needs to be more precise and to convey towards personalized medicine. The human-induced pluripotent stem cells (iPSCs) have a strong potential in engineering organ-on-a-chip since they are derived in a patient-matched manner which makes them a superb source to construct human models for personalized drug screening as well as for understanding patient-specific fundamentals of diseases. To provide novel miniaturized platform for investigation of rare diseases able to address the burning issues in precision medicine today, CISTEM will bring together and synergistically several highly promising research directions which are too often investigated separately at the academic level but also at the industrial level. Based on 4 work packages, the CISTEM RISE project will be implemented by exploiting the complementary expertise of its partners and creating synergies between them through the targeted secondments of staff.


**Key
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Hydropower Extending Power System Flexibility' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

The ultimate objective of the XFLEX project is to increase hydropower potential in terms of plant efficiency, availability and provision of flexibility services to the Electric Power System (EPS).The high Renewable Energy Sources (RES) scenario of the decarbonisation process relies on a drastic change of the European Union EPS with a massive integration of non-dispatchable RES and disconnection of the so-called conventional units, as greenhouse gases emitters. These changes influence drastically the provision of the power grid balancing, and challenge the EPS operations and safety. It is of upmost importance to provide reliable solutions to support the EPS with more flexibility services. Hydroelectric Power Plant (HPP) already significantly supports EPS flexibility in terms of regulation capability, fast frequency control, fast start/stop, fast generating to pumping modes transition, high ramping rate, inertia emulation, fault ride through capacity, etc. XFLEX aims to demonstrate an innovative methodology for system integration of hydroelectric technology solutions, variable speed being a key component and a reference, to provide further enhanced flexibility services assessed by a crosscutting analysis of their impact on both the technology and the market aspects. Innovative solutions also target an optimize maintenance plan to decrease the outage time and increase the availability of the plant. Demonstrations are scheduled in the cases of run-of-river, storage and pumped storage HPPs and they cover cases of refurbished, uprated and especially existing HPP to be applied and scaled to any unit size. XFLEX draws the roadmap for the exploitation of its solutions to all the European HPP fleet. A strategic dissemination plan is set to promote the deployment of the demonstrat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Networking the Sky for Aeronautical Communications' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

Within its strategic research agenda, ACARE (Advisory Council for Aeronautical Research in Europe) indicates that powerful communication is a key enabling factor for the future Air-Traffic Management (ATM) development in Europe required to support the expected sustainable growth of European air transport. However, already today bottlenecks in Air-Traffic Control (ATC) and ATM communication exist. Moreover, the expected ATM paradigm shift towards more strategic and tactical planning requires additional communication capabilities which are not yet available in current ATC/ATM communication systems.Currently, several European research initiatives with the goal to develop improved communication technologies for aeronautical communication are conducted. These initiatives comprise ground-based, satellite-based, aircraft-to-aircraft and airport communication for all different application classes, like ATC/ATM communication, airline operational and administrative communication.