RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Cooperation and Support for MSCA NCPs' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

The objective of MSCA-NET is to facilitate the transnational co-operation between National Contact Points (NCPs) for the MSCA in order to achieve a consistent and harmonized level of NCP support. Next to developing support for the facilitation of daily challenges for all NCPs, we put the focus on lowering the entry barriers for new NCPs and offer particular support services for Widening and Third Country NCPs. This will in turn simplify the access of potential MSCA applicants all over the world, in particular from Widening and Third Countries. We thus contribute to the decrease of the R&I gap between EU Member States/Associated Countries and Widening/Third Countries. We aim at a higher quality and quantity of applications from non EU-Member States/Associated Countries. We will achieve our goals by a wide array of measures: Career Development Support for NCPs in the form of Trainings, Twinnings and Mentoring; the development of a tool box for both NCPs and the scientific community; and strategic capacity development and the creation of synergies with and among MSCA stakeholders. This includes systematic outreach to the non-academic sector. The project is structured into 5 Work Packages and has 27 Beneficiaries and 4 Associated Partners from all levels of experience and among all Horizon Europe country groups. The baseline for our support services to NCPs is a benchmarking exercise whose results will be fed into the various relevant tasks. We ensure the expected project impact by strategical monitoring of the project actions and well planned communication, dissemination and exploitation measures such as the development of an innovative project dashboard. The project's outcomes will be fed back to policy developers and stakeholders within clearly defined processes in order
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Towards Automated Interactions between the Internet and the Carrier-Grade Management Ecosystems'.

assistant: **Objectives**

There is a wide consensus among telecom vendors and operators that the next decade will see a mélange of evolving Internet architectures embedded into high-bandwidth technologies and carrier-grade systems for control and management. The combined Internet Protocol (IP) and Ethernet-based optical transport solutions are expected to drastically lower capital and operational expenses and improve overall network performance. Central to this premise is the concept of autonomic network management, offering a radical improvement in the way Internet can interact with the transport layers, making automated use of available capacity and physical interconnectivity.Unfortunately, practice lags far behind this promise. The segmentation of IP and carrier-grade technologies has not only produced the carrier's organizational separation, but also a fragmentation of the technical competence through separate Network Management Systems (NMSs). In the isolated Internet and carrier-grade management ecosystems, even simple operations, such as IP link upgrades, require multiple human-assisted configurations, and are far from automation. As a result, carriers are seeking ways to alleviate the dependency on manual processes that do not only create management expenditures, but also lead to a heavy overprovision of the IP network.In the project ONE, we propose to alleviate the current isolation between the IP and carrier-grade management ecosystems. As first step towards a commercially-viable autonomic management solution, we plan to design and prototype an ontology-based communication adapter between the two NMS systems, enabling: i) automated provisioning of IP topologies and services; ii) policy-based setup/release of resources; and iii) coordinated self-healing. We emphasize that the solution d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Building body representations: An investigation of the formation and maintenance of body representations' (BODYBUILDING) under Seventh Framework.

assistant: **Objectives**

The body is ubiquitous in perceptual experience and is central to our sense of self and personal identity. Disordered body representations are central to several serious psychiatric and neurological disorders. Thus, identifying factors which contribute to the formation and maintenance of body representations is crucial for understanding how body representation goes awry in disease, and how it might be corrected by potential novel therapeutic interventions. Several types of sensory signals provide information about the body, making the body the multisensory object, par excellence. Little is known, however, about how information from somatosensation and from vision is integrated to construct the rich body representations we all experience. This project fills this gap in current understanding by determining how the brain builds body representations (BODYBUILDING). A hierarchical model of body representation is proposed, providing a novel theoretical framework for understanding the diversity of body representations and how they interact. The key motivating hypothesis is that body representation is determined by the dialectic between two major cognitive processes. First, from the bottom-up, somatosensation represents the body surface as a mosaic of discrete receptive fields, which become progressively agglomerated into larger and larger units of organisation, a process I call fusion. Second, from the top-down, vision starts out depicting the body as an undifferentiated whole, which is progressively broken into smaller parts, a process I call segmentation. Thus, body representation operates from the bottom-up as a process of fusion of primitive elements into larger complexes, as well as from the top-down as a process of segmentation of an initially undifferentiated whole into
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Innovative approach to an Individualised T-Cell Immunotherapy for cancer, using Personalised Tumour Trained Lymphocytes (pTTL) that is reliable, cost-effective, scalable and easy to implement' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

NEOGAP has developed a groundbreaking personalised adoptive T cell therapy for treating solid tumours based on two proprietary technologies: PIOR machine learning software and EpiTCer. This cancer immunotherapy consists of producing personalised Tumour Trained Lymphocytes (pTTL), which are autologous T-cells harvested from regional lymph nodes, subjected to a neoantigen-driven T-cell stimulation technology to deliver highly tumour-reactive T-cell clones (pTTLs). pTTLs are re-infused to the patient where they infiltrate and kill cancer cells, leaving healthy cells untouched. The therapy is broadly applicable to many cancer types, being personalised to each individual patient. In this EIC accelerator project, NEOGAP plans to complete a phase I/IIa clinical trial of the therapy in advanced colorectal cancer patients, focused on safety assessment and biomarker exploration and optimise the manufacturing process for the next clinical studies.


**Keywords:** autologous immune enhancement therapy,Adoptive T cell therapy,immunooncology,Neoepitope,neoantigen,personalised cell therapy,cancer immunotherapy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'SOLAR THERMOCHEMICAL PRODUCTION OF FUELS' (SUNFUELS).

assistant: **Innovation**

The research is aimed at the efficient production of solar fuels from H2O and CO2. Solar thermochemical approaches using concentrating solar energy inherently operate at high temperatures and utilize the entire solar spectrum, and as such provide thermodynamic favorable paths to efficient solar fuel production. The targeted solar fuel is syngas: a mixture of mainly H2 and CO that can be further processed to liquid hydrocarbon fuels (e.g. diesel, kerosene), which offer high energy densities and are most convenient for the transportation sector without changes in the current global infrastructure. The strategy for the efficient production of solar syngas from H2O and CO2 involves research on a 2-step thermochemical redox cycle, encompassing: 1st step) the solar-driven endothermic reduction of a metal oxide; and 2nd step) the non-solar exothermic oxidation of the reduced metal oxide with H2O/CO2, yielding syngas together with the initial metal oxide.  Two redox pairs have been identified as most promising: the volatile ZnO/Zn and non-volatile CeO2/CeO2-δ.  Novel materials, structures, and solar reactor concepts will be developed for enhanced heat and mass transport, fast reaction rates, and high specific yields of fuel generation. Thermodynamic and kinetic analyses of the pertinent redox reactions will enable screening dopants. Solar reactor modeling will incorporate fundamental transport phenomena coupled to reaction kinetics by applying advanced numerical methods (e.g. Monte Carlo coupled to CFD at the pore scale). Solar reactor prototypes for 5 kW solar radiative power input will experimentally demonstrate the efficient production of solar syngas and their suitability for large-scale industrial implementation. The proposed research contributes to the development of tech
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'READY-TO-EAT FOOD FOR BREAKFAST AND SPORT ACTIVITY WITH HIGH CONTENT OF NUTRACEUTICS PREVENTING DISEASE AND PROMOTING PUBLIC HEALTH' (NUTRA-SNACKS).

assistant: **Innovation**

The present proposal suggests the application of plant cell and in vitro culture systems together with a biotechnological approach to provide facilities for the production of new high quality ready-to-eat food with functional activity useful for promoting public health. Nutra-Snack aims at the production of food at high content of natural metabolites with the following recognized health activities: anticancer, antilipidemic, anticholesterol, antimicrobial, antibacterial, antifungal, antiviral, antihypertensive, anti-inflamatory and antioxidant activity etc. The team, which is composed of 5 European countries and a candidate country (6 research institutes and three SMEs) has the main objectives in the following: 1)Selection of organisms producing natural biologically active metabolites with recognized anticancer, antimicrobial, antibacterial, antifungal, antiviral, antihypertensive, anti-inflamatory, anticholinergics and antioxidant activity. 2)Realization of a bioreactor/sensors for innovative plant cell and in vitro systems suitable for nutrient production; protocols for production of biological material enriched on functional metabolites which counteracts the main health risks. 3)Use of genetic transformants in order to enhance the synthesis of the desired metabolites as ???biological factories??? for further extraction of functional metabolites for food additives 4)The production of new ready-to-eat food for breakfast, snacks and for the nutrition of those involved in sports will receive highest priority 5)Development of safety and quality control protocols for the new ready-to-eat-food 6)Contribution to define a standard for new regulations on Nutraceutics...
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Modeling spontaneous Breast cancer metastasis TO the Bone with a first-of-its-kind 3D device that recapitulates physiological tissue-level complexity.' under Horizon 2020.

assistant: **Concept**

Cancer patients developing a metastatic disease are considered incurable. Breast cancer hits 1 woman in 8, and its most common metastatic site is the bone. A major hurdle to overcome breast cancer mortality is the lack of understanding of dynamics leading to the spread of breast cancer cells to the bone. Consequently, metastasis-suppressing agents have not been found to date, neither as newly developed drugs nor as repurposing of existing ones. The aim of the B2B device is to generate a first-of-a-kind 3D model of spontaneous breast cancer metastasis to the bone to dissect the complexity of the metastatic process and empower high-throughput drug screening in a physiological context. B2B will pursue its goal of developing a novel hybrid device able to 1) propagate patient-derived tumor organoids of clinically-relevant dimensions, with their own self-assembled micro-capillary networks, which are 2) continuously linked to a 3D bioprinted macro-vascular tree, organized in a hierarchical branched structure, connected in a closed circuit with 3) a vascularized marrow-containing bone ossicle, as the metastatic target. This is a unique approach, spanning the micro (single circulating metastatic cells, passing the endothelial barrier of capillary networks) to macro (tumor organoids and ossicles of clinically relevant size and tissue composition, connected by a hierarchically organized vascular tree) continuum to recapitulate spontaneous bone metastasis formation in breast cancer. This technology will transcend the limitations of current in vitro technologies, enabling physiological tissue-level complexity with organoids comprising several million cells, and its expected impact will be three-fold: to recapitulate the spontaneous metastatic process in breast cancer, to provide a b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Predictive Analysis on the Worlwide Energy Sector' to be submitted under Horizon 2020.

assistant: **Abstract**

New technological, economic, geopolitical and social fault lines are shaking the foundations of two of the global economy’s most important sectors: energy and  ICT. The energy system is facing a critical and urgent transition toward a cleaner, more affordable and sustainable model with associated costs estimated in the 100s of trillions euros over the next decades. In this context, strategic operational and investment decisions should be based on reliable, accurate and actionable information, often unavailable. At the same time, the ICT sector must develop new technologies as machine learning and advance signals processing to treat an unprecedented volume of alternative data. The energy sector could then highly benefit from the ICT’s big data disruption to the success of its transition.Combining deep sector (energy) and technology (data science, machine learning) expertise to provide new and valuable information for greater transparency in energy markets and operations, Kayrros ambitions to become the European tech champion in business intelligence and analytics. Commingling commercially available data from sensors, satellites and the web, Kayrros has placed R&D at the heart of its development and growth strategy since its inception in 2016. Built by European talents with a global ambition, the company has consolidated a leadership position as the reference alternative data provider for the energy market and is now expanding into new sectors.Thanks to its proprietary technology, Kayrros aims to create and lead a new multi-billion-euro market, by being the first provider of automated real time observation of industrial assets worldwide. Hence, Kayrros has built a highly automated asset-centric database and visualisation platform, which has been rolled-out and commerciali
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Safe and eco-efficient packaging solutions for the food industry.'.

assistant: **Innovation**

The primary aim of this network is to disseminate the spread of eco-friendly, recyclable food packaging technologies across Europe. The focus of the network is on recyclable food packaging which will ensure the development of safe and efficient packaging and processing technologies to maximise food quality and encourage eco-friendly practices. At present recyclable food packaging is a rapidly developing field which is experiencing continuous technological changes and increases in volume. The project will seek to establish new technologies and practices in the field of recyclable packaging and raise know-how throughout the European industry. This will be achieved by combining the ongoing R&D activities with other initiatives that will embrace education, legislation and technology transfer.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Photonics for engineered quantum enhanced measurement' (PEQEM) under Horizon 2020.

assistant: **Objectives**

Advances in measurement always lead to dramatic advances in science and in technology. Our society is now heavily dependent on the sensors that permeate environmental monitoring, security, healthcare and commerce. This is quantified by the global sensing market worth rising from $110 billion in 2015 to $124 billion in 2016, and is predicted to continue to rise to $240 billion by 2022. Now, our rapidly growing understanding of how to control quantum systems vastly expands both the potential performance and application for measurement and sensing using quantum-enhanced techniques. But these techniques will only efficiently find disruptive use once they are engineered for robustness, deliver desired operational parameters and are shown to work in a platform that can be mass-produced.This project adopts an engineering approach to the disciplines of photonic quantum enhanced sensing and squeezed light quantum optics. We will develop integrated photonics that are tailored to enable miniature, deployable and ultimately low cost sensors that exceed the state of the art through (i) exploitation of the quantum mechanics of light and by (ii) developing the requisite high performance of components in an integrated photonics platform. The methodology is to combine quantum optics of Kerr-nonlinear materials that generate squeezed light and quantum state detection with photonic device engineering. We will benchmark device performance using quantum metrology techniques. By the end of this project, we will have developed all-integrated squeezed light generation and detection technology, that provides enhanced sensors for absorption and phase measurements beyond the shot noise limit --- the hard limit that bounds performance of state of the art “classical” sensors. Applications include n
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Optimal stochastic control of financial risks under utility-based preferences'.

assistant: **Concept**

I plan to develop new constructive probabilistic methods for the risk-averse valuation and the optimal hedging of financial risks with respect to utility based preferences. The mathematical problem is well characterized by martingale and convex duality methods, but constructive and explicit solutions are limited so far. My thesis contributes such solutions for two innovative new classes of stochastic market models. In a discrete semi-complete model, a direct computation scheme is provided. In a continuous time Markovian model which allows for various mutual dependencies between tradable and further untradable factors of risk, both the utility-based valuation process and the hedging strategy are described by a semi- linear system of reaction diffusion equations. Using these results, I plan to analyze the asymptotic relation of the utility based approach to the valuation and hedging problem to related alternative approaches, and to develop approximative and asymptotic solution methods. More precisely , I want to study - the convergence of the solutions for discrete approximations of continuous models, - the dependence of the solution from the level of risk aversion, and - the asymptotic behavior of both the hedging strategy and the valuation process when the risk aversion tends to zero. The results should be used for a detailed qualitative and quantitative analysis of concrete application examples like weather derivatives or credit-risky securities. These have been studied only by related ( marginal - utility ) approaches so far - basically without addressing the crucial hedging problem.