RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Dynamic capabilities growth and long-term competitiveness of European firms - a diagnosis and the implications for eU policies', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The purpose of this project is to develop and improve some novel and useful conceptual tools and their policy implications for guiding the search and exploitation of technological, production and marketing competencies within and across business firms. More preciseluy, our project is meant to examine: (i) Corporate policies designed and implemented by business organizations located in Europe, particularly the processes by which they define their technological and competitive space, the processes by which corporate organisations explore and exploit new opportunities of innovation and diversification - regarding not only new technologies, but also forms of coordination, production, marketing strategies; (ii) The influence of organisational structures (that is corporate governance structures) adopted by firms located in Europe upon these patterns of search and their effectiveness. Our project will investigate the mutual interactions between corporate governance structures (e.g., the set of incentive mechanisms adopted in a functional or a multi-divisional structure), the organisation of RTD and production activities, particularly at the international level, and technological development and sustainable competitive advantage; (iii) The organisation of interfirms relationships (e.g., collaborative agreements, minority participations and M&As). In this respect, our project aims to analyse various types of linkages among local large firms (including multinational corporations) and and small firms as a source of technological and organisational learning. It is important to assess the significance of knowledge and learning produced by networks of firms, especially those promoted by the EU; (iv) the comparative importance of technological spillovers accruing to SMEs from extra-Eu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Serological identification of human tumor antigens as a basis for specific active immunotherapy of human neoplasms', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Objectives:The development of specific vaccination approaches for immunotherapy of human neoplasms highly depends on the availability of human tumor antigens, which are exclusively expressed in human tumor cells. The aim of this proposal is to identify and characterize new tumor antigens using the SEREX (serological analysis of recombinantly expressed tumor antigens) approach.SUMMARY: The development of specific vaccination approaches for immunotherapy of human neoplasms highly depends on the availability of human tumor antigens, which are exclusively expressed in human tumor cells. The aim of this proposal is to identify and characterize new tumor antigens using the SEREX (serological analysis of recombinantly expressed tumor antigens) approach. The first part of the study deals with the molecular identification of new tumor antigens in a defined spectrum of human neoplasms. We will focus on neoplasms which are difficult to analyse by T-lymphocyte based methods since the SEREX approach does not depend on the availability of specific T cell clones and cultured tumor cell lines. This will include breast carcinomas, prostate carcinomas, colon carcinomas and lung carcinomas. These neoplasms represent over 60% of the malignant diseases of the adult, but only a few antigens have been identified, which are expressed in these types of tumors.The initial molecular characterization of new antigens will involve sequence analysis, expression analysis at the transcriptional level and genomic investigations including the localization and cloning of the genes coding for the identified transcripts. The precise analysis of expression and subcellular localization of the tumor antigens will be achieved by immunocytological and immunohistological analysis using monoclonal antibodies. In t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'New full-electric propulsion system, completely submerged in water, for zero-emissions navigation'.

assistant: **Concept**

The goal of our project is to launch on the boating market a zero-emissions propulsion system that can be installed on boats up to 10-12 metres long. This goal will be reached by developing an electric propulsion system that is completely submerged in water.  With its wide range of power (10-25-50 Kw) and high endurance (over 2 hours), it will be able to be installed on both pleasure craft and passenger boats.The strength points of our solution will be:- integration of motor, propeller and power-assisted steering into a housing submerged in the water.  This latter feature is particularly important, since it significantly simplifies the mechanical design of the motor, which will no longer require a cooling system. The unit will be particularly compact, so the technology can be used even on small to mid-sized boats;- an operating endurance that can be varied to meet the individual requirements of final users by having the option of installing batteries that are more or less powerful and which can even be supplemented with other energy production technologies such as photocells, mini-wind power and a small endothermic generator for emergency use.        The new propulsion system drives the propeller shaft directly.  No reduction gear is used, thus mechanical losses are eliminated.A sophisticated software control system will be developed to allow manoeuvres in tight waterways, even using a joystick. More precisely, when two motors are installed in parallel, the system will allow each motor to turn independently, thus allowing lateral movement that would not otherwise be possible. To further enhance the project, a BMS (battery management system) has been specifically developed to control the batteries.   We plan to offer a solution that fully meets the needs of the market re
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Uncovering the origin and mechanisms of Down syndrome-associated leukaemia through human induced pluripotent stem cell-derived haemopoiesis' under Horizon 2020.

assistant: **Concept**

This project aims at dissecting the contribution of yolk sac (YS)-derived haemopoietic progenitors to childhood leukaemias, whose early onset suggests an embryonic origin. Using induced pluripotent stem cell (iPSC) differentiation, we will determine the origin of the Down syndrome-associated transient myeloproliferative disease (DS-TMD), paradigmatic example of perinatal malignancy. TMD, due to megakaryoblast hyperproliferation, has an in utero origin. This supports the compelling hypothesis of a haemopoietic stem cell (HSC)-independent origin of DS-TMD, as during embryogenesis there are at least 3 waves of progenitors with megakaryocytic potential. A first primitive program, followed by the erythromyeloid progenitors (EMP), both YS-derived and devoid of HSC potential; lastly a definitive program, generating HSCs and all haemopoietic lineages. By differentiating iPSCs from a DS-TMD patient through recapitulation of embryonic development, we will interrogate the contribution of primitive, EMP and definitive haemopoiesis to DS-TMD with in vitro/in vivo functional assays. Moreover, we will investigate the molecular mechanisms triggering the disease. As mutations leading to a short GATA1 isoform occur in all cases of DS-TMD, we will analyse how this affects the transcriptional landscape of the cells relevant to the disease. We hypothesise that DS-TMD derives from a rarely appreciated developmental program (the EMP), whose life-long contribution is only beginning to be elucidated. Determining the developmental source and mechanisms of this disorder could help designing new therapies for myeloid malignancies in non-DS patients and could lead to a paradigm shift in the field of haemopoiesis and leukaemogenesis. Research on cancer and childhood leukemias is of broad interest fo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Understanding The Fluid Mechanics of Algal Bloom Across Scales'.

assistant: **Objectives**

One of the most life-threatening consequences of global warming is the perturbation of natural ecosystems. Among the detrimental impacts, the increased frequency and intensity of Cyanobacterial blooms (overgrowth of microscopic bacteria in aquatic systems) seriously threaten drinking water and devastate ecosystems and the economy.The challenge now is to accurately predict the formation of Cyanobacterial bloom and find feasible mitigation strategies. This poses a new paradigm in complex fluids and flows where rheology, fluid mechanics, and biophysics are intertwined across scales: (1) rheological properties on the microorganism level (few microns), (2) mesoscopic phenomena of formation and fragmentation of Cyanobacterial colonies (hundreds of microns), and (3) macroscopic dispersion of colonies under laminar and turbulent flows in the aquatic system (meters). Hence, fundamental knowledge of rheology and fluid mechanics of Cyanobacterial bloom formation is urgently needed.I will tackle this multiscale problem with a set of highly controlled laboratory experiments and numerical simulations. The novel experimental setups combine rheological methods with advanced mechanical manipulation of cells, tomography, particle tracking, flow visualization, and microscopy. The combination of experiments, statistical modeling, and simulations will result in many first-ever measurements and analyses, unravelling the rheological and mechanical properties of the cells/colonies, and revealing details of aggregation and fragmentation of Cyanobacterial colonies under various hydrodynamic and environmental conditions.This project lays out an ambitious effort to overcome current limitations and uncover the complex multiscale interactions between rheology, fluid mechanics, cell biophysics, and c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The Human Face of AI' (Furhat), addressing dissemination and exploitation.

assistant: **Impact**

Interacting with AI by talking is becoming increasingly common. Today we can order food, find out currency exchange rates & get answers to FAQs by messaging bots running in Facebook, WhatsApp or Telegram. Virtual assistants like Apple Siri, Amazon Alexa or Yandex Alisa migrate from smartphones to smart speakers in our living rooms. Simultaneously we are witnessing the emergence of social robots—a new class of robots for whom social interaction plays the key role.A social robot is a robot that can show emotions, have capabilities to converse on an advanced level, understands the mental models of its social partners, forms social relationships, makes use of natural communication cues, shows personality & learns social capabilities . In essence, a social robot = robot or AI + social interface.There are serious technological problems to broad acceptance of social robots & the main one is the non-realistic interactions.At Furhat Robotics we are developing the 1st scalable social robotics platform. Furhat, the robot built on this platform, is a fully programmable social robot capable of expressing a broad range of emotions & carrying out a realistic conversation with humans.We have sold 80+ Furhats to 50+ customers—Disney, Intel, Merck, KPMG, Swedbank, Deutsche Telekom, Honda & others. Finally, we are an official partner of the Dubai Expo2020 exhibition.In total we have generated €2.1m in early revenues. In Sep 2017 we raised €2.13m of venture capital from Balderton Capital & LocalGlobe (both from the UK).We are aiming at creating completely new markets for social robotics solutions. We are aiming at commercialising ~10,000+ Furhat robots by 2023, generating €30m in annual revenues. Long-term, we believe we can become the next Swedish & European unicorn company, exceeding the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Use of novel techniques to identify pathogenic versus non-pathogenic TH17 cells in experimental autoimmune encephalomyelitis, a murine model of multiple sclerosis.' in the context of a Horizon 2020 call.

assistant: **Objectives**

The aim of this Fellowship is for the researcher, Dr Karen Dixon, to receive advanced training, develop interdisciplinary skills with high-impact dissemination, and practical experience in line with a leading independent researcher in the EU. The remit of the Fellowship proposal falls under the category of Immunology- autoimmunity and TH17 cell biology. The researcher will be based for two years in the laboratory of Professor Vijay Kuchroo at Brigham & Women`s Hospital. The third year of the Fellowship will be completed in the Department of Biochemistry & Immunology, Trinity College Dublin (TCD) working under the supervision of Professor Kingston Mills. Research training will be implemented through an interdisciplinary project investigating the mechanism by which IL-23 regulates the development of pathogenic vs non-pathogenic TH17 cells. On the outgoing phase of the Fellowship, the researcher will access expertise, state-of-the-art training and mentoring in deciphering the heterogeneity of TH17 cells using advanced transcriptional analysis. In the return phase the researcher will consolidate the knowledge and experience gained in the US through further laboratory training in IL-17 mediated disease. In TCD she will be given the opportunity to embed her new knowledge in Ireland through mentoring and teaching in the host institute. This includes practical seminars on state of the art technology including single cell RNA-seq and NanoString technology. Under the guidance of international experts, she will acquire an invaluable skillset using the latest technical advances to decode heterogeneous populations in immune mediated diseases. The resources of the host departments will facilitate development of an interdisciplinary and international academic network as well as career
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Searching for novel catalytic rnas and splicing systems in modern genomes' to be submitted under Fourth Framework.

assistant: **Abstract**

Research objectives and content This project aims to identify novel active RNAs among the products encoded in contemporary genomes. By active RNA, I mean both RNAs that catalyse reactions on their own or with the help of cofactors, and RNAs with catalytic activity that depends on the presence of proteins such as those involved in protein-assisted splicing systems. Except for RNase P, all currently known catalytic RNAs get involved into auto-circularization processes which facilitate their survival, replication and/or integration into other DNA or RNA molecules: selection for self-circularization should constitute a general route for recovering molecules that catalyze transesterification. I have set up an in vitro selection protocol devised to isolate among a genome the sequences encoding for molecules able to self-circularize. The same procedure could also be carried out sing cellular extracts, which might allow to detect the products of any reconstitutable splicing system. Training content (objective, benefit and expected impact) I will join Dr Smith's laboratory to learn how to prepare and manipulate splicing competent extracts. My plans are to use this stategy to investigate the genomes of a number of bacterial and archaebacterial species living in extreme environments, as well as the genomes of primitive eucaryotes such as diplomonadida which infect mammalian cells. Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Development, construction, integration, and progress toward to two-phase device monitoring and qualification on aircrafts' (AEROL-HP).

assistant: **Innovation**

The proposed project is part of the Cleansky Eco-Design activities for the all (or more) electric aircrafts. The main targets of the call are related to improved aircraft weight, improved electronic equipment life cycles & reduced maintenance thanks to the use of highly efficient passive (“green”) thermal control systems (as already used on satellite systems).Technical objectives:The EHP proposal is part of the ECO-Design ITD and will address the development, and qualification aspects of highly efficient two-phase cooling devises such as heat pipes and loop heat pipes to be used on board of aeronautical aircrafts.The main objectives are :•Qualify two-phase heat transfer devises in accordance with specific aeronautical requirements such as :oHigh acceleration loadsoLong duration vibration stresses•Reduce global aircraft weight at equipment and/or system level => reduce aircraft consumption and increase operating range•Lower impact on environment through the use of passive and maintenance free thermal equipments•Increase reliability of controlled equipment (power electronics) => decrease repair and maintenance aspectsThe Ammonia HP and LHP products are today baselined (with a TRL 9) on all Space satellites or payloads thanks to the reliable capability provided by these “isothermal” lightweight thermal management devises.Non-space applications are also more and more considered for these two-phases devises to be used on high power electronic (railway applications) or primary flight control actuators.The AeroL-HP products will be developped up to CDR level with qualification of the two-phase hardware. From a technical side, the proposed thermal link will have to provide a reliable and competitive (generic, modular and low cost) product (Rejected power/mass). The thermal link
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Diversity in the United Nations Peacekeeping Bureaucracy' (DIVUNPKO) under Horizon Europe.

assistant: **Objectives**

Diversity in the United Nations Peacekeeping Bureaucracy (DIVUNPKO) addresses two critical issues. On the one hand, geographicaldiversity is a peculiarity of International Organizations’ staff like the United Nations (UN) and the European Union. Yet, in theliterature, we have little knowledge about the impacts of staff diversity on the functioning of International Organizations (IOs). On theother hand, scholars have started to acknowledge the importance of diversity in peacekeeping operations but have studied it only formilitary staff. The present project fills these gaps by examining the impact of staff geographical diversity in the case of peacekeeping operations, the main tool of the UN for maintaining international peace and security. It adopts an interdisciplinary perspective by bridgingdiversity research in Public Administration and the literature on IOs and peacekeeping in International Relations. This two-year projecthas three objectives: (1) to collect socio-demographic data on civilian staff working in UN peacekeeping operations, 2) to develop an analytical framework to study diversity effects within IOs, and (3) to examine empirically the effects of geographical diversity among civilian peacekeepers along three dimensions: throughput, output and legitimacy. This project will make key contributions to the research on peacekeeping, international bureaucracies, and diversity. At the societal level, this project hopes to impact the work of international civilian missions and sensitize the public to issues of diversity in public organizations more broadly.


**Keywords:** peacekeeping, diversity, United Nations, international organizations