RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Nucleobase derivatives as drugs against trypanosomal diseases' (TRYPOBASE) under Seventh Framework.

assistant: **Objectives**

The protozoan diseases, leishmaniasis, African trypanosomiasis and Chagas’ disease are responsible for substantial global morbidity, mortality, and economic adversity, and in most countries, existing strategies for control and treatment are either failing or under serious threat. New tools for combating pathogenic protozoa and the development and exploitation of new drug targets are required. This proposal builds on several achievements and observations of the consortium in the area of nucleotide metabolism. •Pyrimidine and purine metabolism exhibits unique features in trypanosomes. •The identification of a unique enzyme involved in pyrimidine metabolism restricted to trypanosomes and essential for viability: the dimeric all-alpha dUTPase. •An exceptional collection of purine and pyrimidine analogues is available through the consortium for antiprotozoal screening and lead identification. •The consortium brings together an outstanding combination of expertise for drug discovery. The main objective is the identification of new purine and pyrimidine derivatives for the treatment of the leishmaniases and trypanosomiases. A two-pronged approach is proposed to discover new leads for the treatment of leishmaniasis and trypanosomiasis targeting nucleoside/ nucleotide metabolism. 1)The phenotypic approach exploring the potential of large collections of novel nucleobase derivatives against trypanosomal diseases. 2)The target-based approach specifically centred on the development of inhibitors of the enzyme deoxyuridine triphosphate nucleotidohydrolase. The trypanosomal enzyme shows structural and functional characteristics which differ profoundly from the mammalian counterpart. The aim is to identify potent inhibitors that are active against parasitic protozoa, active in rodent m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Efficient Synthesis using Alkynes as Masked Ylides' (ESAMY), addressing dissemination and exploitation.

assistant: **Impact**

The chemicals arena is vital to our continued way of life, be it though materials synthesis, agrochemicals, pharmaceutical production or in biological probes. All these areas depend on our ability to make molecules. This is achieved by the coupling of fragments, and the manipulation of various functionalities. This process can be time-consuming, produce large amounts of waste material and require the use of significant amounts of limited resources, not least energy and chemical precursors. Therefore it is vital that we develop more efficient, cleaner and quicker strategies for molecular synthesis. The current best methods to prepare the valuable reactive intermediates known as sulfur ylides, employ the use of complex and potentially dangerous functionalities. As these are ultimately lost from the material, only after having been introduced at significant cost, these routes are rendered unattractive in terms of safe-handling and synthetic efficiency. In this proposal we show a way in which sulfur-ylides can be prepared directly from simple, readily available precursors, without the currently associated problems. This method employs gold catalysis, and will be used to develop new reactions that allow the preparation of complex molecules by the coupling of simple units. The products will be of significant use, as either final targets or in synthesis of compounds of importance. In this proposal, new reactions will be developed that show high synthetic efficiency and flexibility. The reactions will be established and their scope and limitations probed to demonstrate their applicability to the chemical community.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'EEN Innovation Management Berlin-Brandenburg (InnoManage BB 2020-2021)' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The overall aim of the action is to help to enhance and accelerate the economic returns from innovation in Europe, by increasing the innovation management capabilities of SMEs. The project sought to address and strengthen the area of innovation management for innovative SMEs in the region of Berlin and Brandenburg. As identified by the European Commission, innovation management is a key area for companies and the inability to manage these processes effectively is a significant barrier to SME innovation and their competitiveness. This is the context in which we attempted to enhance the innovation competence of Berlin and Brandenburg based companies.The proposed project is an integral part of the Enterprise Europe Network activities in Berlin and Brandenburg for the next period 2020-2021. The project addresses two main objectives, which are pre-defined by the European Commission and aimed for a limited number of small and medium sized enterprises in Berlin and Brandenburg:1. The first main objective for InnoManage BB consortium is to ensure that key SME beneficiaries of Horizon 2020 funding schemes EIC Pahtfinder, EIC Accelerator (SME Instrument) and  Fast Track to Innovation (FTI) will receive appropriate Key Account Management KAM services which should be complemented by coaching services. The objective of this service is to identify weaknesses in the innovation capacities of the SME beneficiaries hindering their growth opportunities and hence their full commercial potential.2. The second main objective is to ensure that SMEs with significant innovation activities and a high potential for internationalization -promising SMEs with gaps in the innovation management systems - will receive high quality innovation support to address those gaps.Whereas the first service packa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'VRE for regional Interdisciplinary communities in Southeast Europe and the Eastern Mediterranean' (VI-SEEM), addressing dissemination and exploitation.

assistant: **Impact**

In the last decade, a number of initiatives were crucial for enabling high-quality research - by providing e-Infrastructure resources, application support and training - in both South East Europe (SEE) and Eastern Mediterranean (EM). They helped reduce the digital divide and brain drain in Europe, by ensuring access to regional e-Infrastructures to new member states, states on path to ascension, and states in European Neighborhood Policy area  – in total 14 countries in SEE and 6 in EM. This VI-SEEM proposal brings together these e-Infrastructures to build capacity and better utilize synergies, for an improved service provision within a unified Virtual Research Environment (VRE) for the inter-disciplinary scientific user communities in the combined SEE and EM regions (SEEM).The overall objective is to provide user-friendly integrated e-Infrastructure platform for regional cross-border Scientific Communities in Climatology, Life Sciences, and Cultural Heritage for the SEEM region; by linking compute, data, and visualization resources, as well as services, models, software and tools. This VRE will provide the scientists and researchers with the support in full lifecycle of collaborative research: accessing and sharing relevant research data, using it with provided codes and tools to carry out new experiments and simulations on large-scale e-Infrastructures, and producing new knowledge and data - which can be stored and shared in the same VRE. Climatology and Life Science communities are directly relevant for Societal Challenges.The driving ambition of this proposal is to maintain leadership in enabling e-Infrastructure based research and innovation in the region for the 3 strategic regional user communities: supporting multidisciplinary solutions, advancing their research
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'THEORETICAL AND EXPERIMENTAL INVESTIGATION OF SYNCHRONOUS SILICON NANOWIRE WAVEGUIDE DISPLACEMENT SENSORS' (NANO-DISP), addressing dissemination and exploitation.

assistant: **Impact**

Recently, an approach using physical contact of suspended nanowire silicon waveguides for optical switching is presented using silicon photonics technology aiming telecommunication field. The demonstrated switch changed its state by in-plane displacement of a movable elliptical waveguide generated by a NEMS actuator. The technique provides sensitivity even to submicron distance/displacement levels and is applicable to various wavelengths. Later, effects of the waveguide tip geometry and relative positioning of the input and output waveguides on the optical characteristics of the waveguide connections are investigated both theoretically and experimentally. Although these efforts were towards realizing optical switches and connections, same approach can well be employed as an optical distance/displacement sensor in demanding silicon photonics devices, and in general, in acoustical, flow, mechanical displacement sensing as an embedded tool. The objective of this proposal is to investigate synchronous silicon nanowire waveguide displacement sensors both theoretically and experimentally. Furthermore, the measurement range and sensitivity can be engineered as the application changes by customizing the waveguide tip geometries. The technique is also extendable to post-micron-level displacement ranges and various wavelengths by proper selection of the waveguide and buffer materials, and appropriate light sources and photodetectors. In the proposed approach, measurement of out-of-plane distances/displacements is also possible by use of optical waveguides. The proposed approach is expected, for the first time, to yield guidelines for a standard and customizable optical measurement technique for embedded synchronous submicron distance/displacement sensors covering slow to very hig
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Boosting the exposome space coverage in the aquatic environment by multidimensional integrated analytical platforms.' under Horizon Europe.

assistant: **Concept**

The increase of anthropogenic chemicals released by human activities poses a growing threat to natural and man-made environments. Characterizing the mixture of chemicals that an individual encounters throughout lifetime, namely exposome, is a complex analytical task that is only partially fulfilled by current state-of-the-art methods. Non-targeted analysis approaches based on liquid reversed-phase chromatography hyphenated with high-resolution mass spectrometry restrict the detectable exposome chemical space to medium-to-low polarity chemicals. The BEspace project seeks to untangle sample complexity and expand the detectable exposome through advanced separation approaches, combined in a two-dimensional fashion and hyphenated with high-resolution mass spectrometers. On this basis, it shall boost the profiling of chemicals of environmental concern in relevant exposome matrices like environmental and treated water samples, thanks to the collaboration with KWR Water Research Institute. Even though two-dimensional liquid chromatography approaches provide increased separation selectivity and capacity, boosting the detectable chemical space coverage of the aqueous samples, their application in exposomics is limited. The complex two-dimensional data structure and the lack of standardized procedures hamper the exposome chemical identification, requiring the implementation of composite cheminformatics tools. Therefore, BEspace will develop advanced wet and dry lab analytical platforms to expand the detectable chemical space of the aqueous compartment. Large-scale quali-quantitative exposomics datasets will be project final outputs, providing cutting-edge data to be publicly shared to enrich present databases and to develop novel risk assessment approaches. The implicit multidisci
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The Imperial Encounter in Early Islamic Egypt:  Dissecting the Aphrodito Archive' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Named ‘Aphrodito archive’ because it originates in that otherwise unremarkable Middle-Egyptian town, the most important papyrological archive of the early Caliphate contains the papers of an early-eighth-century district administrator, including correspondence with the provincial governor in the new Muslim capital Fustat, and with village heads in his district, as well as registers and accounts generally related to tax and resource extraction.Known for over a century, the Aphrodito archive remains underexploited, largely because of its inaccessibility. Its three languages (Arabic, Coptic, Greek), difficult-to-access editions, and lack of translations have acted as a break to its study, and the partial nature of the existing translated texts (mainly those coming from above) has created a skewed view of its nature, which is much more organic and dialectical than has been allowed for. IMPERIAL ENCOUNTER will make this invaluable group of documents available to scholars by providing a full translation of the archive’s documentsIMPERIAL ENCOUNTER will also use this archive to produce a microhistory of the Aphrodito area and its engagement with the new empire. Containing documents from above and from below, the archive admirably illustrates the Caliphate’s conception of empire and its implementation strategy on the one hand, and local reception empire on the other. A team with the necessary linguistic skills will produce several microhistorical studies exploring some key questions for the Umayyad caliphate and the functioning of early medieval empires: the balance between coercion and negotiation, the role of archives in establishing power, the indigenous reception of empire.In this key period of ostensible power display by the Umayyads, the documents found in rural Aphrodito
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'INNOVATIVE DOCUMENT ENGINEERING APPLICATION' to be submitted under Fourth Framework.

assistant: **Abstract**

The overall purpose of IDEA is to boost the productivity of information providers through a generic telematics platform-independent solution for help with authoring, accessing and distribution of information. The project will adopt structured documents at each information processing stage, with bilingual documents used as the basis of a multilingual system, while information access and retrieval will rely on intelligent querying techniques and logical and semantic structures. IDEA may also develop methods to capture the implicit structure of existing printed or electronic documents and images, facilitating their integration in a local user environment.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Developing European standards for bee pollen and royal jelly: quality, safety and authenticity'.

assistant: **Innovation**

The competitiveness of the European beekeeping sector is progressively falling due to the reduction of beekeepers’ production as a direct consequence of decrease in bee population, implying lower economies of scale, underutilised resources and higher relative production costs. In addition, beekeeping products produced in countries with much lower quality standards, even sometimes adulterated with substitutes and complemented with sweetening products, are gaining market share in Europe through an unfair competition. In addition, there is a current lack of standards at European (and international) level for certain bee products like pollen and royal jelly. This means that it is possible to find in the market products under these labels without any control of quality and authenticity, and the risks it may imply for both the consumer and the SMEs of the sector. Few countries in Europe have some guidelines or regional standards for other products than honey, but broad standardization is missing. Therefore, the objectives of this project are threefold: (a) To develop European standards for bee pollen and royal jelly (b) Establishment of the health relevant criteria for pollen and royal jelly (c) The development of an unerring methodology for the determination of pollen and honey origin authenticity Claims made by several European Associations of beekeepers about the lack of quality controls in both marketed pollen and royal jelly for human consumption give rise to the developing of such standards. The standards and methodologies that will be developed in this project could lay the foundations of future European regulations. Research and development activities will include analytical methods to determine sensory properties, microbiologic load and chemical composition of mentio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Optimal Control of Quantum Optical Systems' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

This project is concerned with the theoretical study of confined quantum optical systems, with the aim of developing a fundamental understanding of few and many-particle systems, as well as engineering techniques for applications in quantum information processing (QIP) with the tools of quantum optimal control theory (QOCT). The main objective of the present project is to bring QOCT and QIP together in order to render the realisation of scalable quantum hardware feasible. The project has been divided in three subprojects: the first one aims to use QOCT to efficiently and quickly move ions between different spatial locations of a ion-chip quantum processor; the second one deals with the transport of Bose-Einstein condensates and the production of non-classical states of these in neighbouring micro-traps by means of QOCT; the last subproject concerns the application of QOCT to engineer quantum phase transitions of many-body systems for QIP purposes, such as the generation of quantum superpositions of macroscopically distinct phases as a result of non-adiabatic dynamics. The last subproject is the most innovative part of the whole project because to our knowledge QOCT has been applied only to single or few particles so far, without exploring the physics that arises from multi-particle entanglement. An important issue that the project aims to address is the development of techniques to deal with presence of noise, dissipation and imperfections, since this is a yet unsolved issue. This is of crucial importance for QIP because to perform quantum operations one needs to reach the demanding thresholds of fault-tolerant quantum computing, that are basically unattainable without optimal control. All of these objectives address some of the most relevant and challenging topics in q