RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The Continuation of Politics with Other Means: War and Protest, 1914-2011' under Horizon 2020.

assistant: **Concept**

This project looks at the political means employed by those who, for various reasons, resorted to protest during times of war in the period from the First World War to the Iraq War. In most cases, the challengers embraced alternative means of political articulation due to the established channels of political decision making being controlled by the supporters of the war in question. Case studies illuminate the manifestations of war-time protest in different wars including both the well-known and some of the ""forgotten wars"": First World War, Spanish Civil War, Second World War, Korean War, Vietnam War, Soviet War in Afghanistan, Falklands War, Kosovo War and Iraq War. The project pursues the objective to articulate the relationship between war and protest and to develop further the debate surrounding war as a channel of cultural, social and political change. It will advance research into the comparative dimension of war-time protest by embedding this investigation in an analytical framework focused on the methods and questions of historical enquiry into social movements, and to give further specificity to the debate on processes of politicisation and depoliticisation with particular focus on the variety of motivations that drove war-time protest beyond just pacifism. This analysis combines methods from the history of protest and social movements, the history of war, the history of political thought as well as film and visual studies. The project provides conceptual tools and evidence on the pre-history of present-day protests, e.g. against U.S. unilateralism in Iraq. Via a number of publications and engagement events, especially in conjunction with public film screenings, it will create impact by intervening in current debates about the repercussions of global warfare
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'BIODEGRADABLE PACKAGING MATERIALS ADVANCING CIRCULARITY, SUSTAINABILITY & ECO-INNOVATION'.

assistant: **Concept**

The design of biodegradable polymer materials (BDPM) is at the core of BioPackMan, aiming to explore an extended material design space of Polyhydroxyalkanoates (PHAs), Poly(butylensuccinate) and its copolymers (PBS, PBSA) and Polylactic Acid (PLA) to develop tailored compounds that harness synergistic effects, leading to biodegradable, recyclable packaging with application-specific mechanical strength, thermal stability, chemical resistance and gas permeability. Biodegradable compounds will be developed with tailored morphology, to meet diverse flexible & rigid packaging requirements and also embrace a ‘biodegradation as a system property’ approach from initial material and packaging design, considering specific environmental conditions for intended and unintended disposal pathways. By establishing a complete value chain (material producers, compounders, packaging converters and end users), BioPackMan aims to provide a complete set of compounds, sustainable additives and innovative processing technologies for the production of sustainable packaging demonstrators for food, home care and personal care sectors. The target is to obtain benchmark fossil-based products quality, ensuring compliance and safe use in packaging, showcasing that BDPMs can be recycled. Circularity, safety, and sustainability are considered at all stages of development through SSbD framework, and liaise with society & industry, to assure interaction, knowledge exchange and adaptation of circular business models. To secure societal impact, stakeholders will be involved early in the project to identify barriers and facilitate the adoption of sustainable practices.


**Keywords:** Biodegradability, PHAs, PBS, biobased polyesters, PLA blend, sustainable additives, digital tools, lifetime prediction, pack
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'MApping the Methylation of repetitive elements to track the Exposome effects on health: the city of Legnano as a LIving lab' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

The concept of exposome encompasses all human disease determinants encountered during the life course. The exposome induces epigenetic modifications (e.g., DNA methylation). Several studies have investigated how repetitive elements (REs) can be switched on in response to environmental stimuli, but have started from the assumption that altered RE methylation is always detrimental to the health of the affected individual. MAMELI proposes an alternative hypothesis that some REs are plastic entities that respond physiologically to the environment; consequently, the ability of DNA to adapt to environmental triggers can be monitored.To test this hypothesis, the MAMELI project will enroll 6200 subjects in the city of Legnano (Italy). The first-level (discovery) will apply third-generation sequencing methylation assessment on 200 subjects at two-time points: T0 (baseline) and T1 (6 months after T0). The discovery level will allow me to define a pool of REs (differential REs) whose methylation can change without impacting genome stability. The second level (tuning) will be conducted on 2700 subjects (200 subjects of the discovery level + 2500 additional subjects) and will allow me to develop an algorithm (MAMELI algorithm) to predict the relationship between exposome and RE methylation status (RE methylation signature). In the third level (validation), I will apply the MAMELI algorithm on the second set of the study cohort (n=3500) to calculate the difference between the measured RE methylation signature and the values predicted by the algorithm. In addition, to test the reversibility of RE methylation following lifestyle modifications and its preventive potential, I will design an intervention study embedded in the cohort.MAMELI would represent a breakthrough in the understandi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Gender Career Gap and Firm Composition' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

As careers progress women tend to lag behind their male peers. This career divergence results in the underrepresentation of women in positions of power, which is bound to bear an important cost to individuals, firms, and society. It is likely to be linked with a misallocation of talent, make the glass ceiling more impenetrable, and hinder future progress towards equality. The focus of this project is on the role of gender composition within firms and occupations on the career divergence of men and women. Relying on high quality administrative data and a credible empirical design, I will estimate how the share of women in a firm affects the gender career gap. Then employing structural estimation approach, I will test the effectiveness of policies aimed at reducing gender imbalances within the workplace, such as quotas or equal opportunity policy. Finally, I will conduct a comparative analysis across European countries to test the external validity of the findings and to draw lessons on the role of institutional environment and how it interacts with different employment policies. The question I address speaks directly to an ongoing global political and economic debate. Advancement towards gender equality is currently one of the priorities of the new Strategic Agenda of the EU. The approach I take is novel and the results have a potential to shed light on the underlying causes of workplace gender imbalances. Finally, the cross-country comparative analysis will add to the relevance of this proposal in a European perspective. The community of the Universitat Pompeu Fabra and Barcelona School of Economics and the supervision by Professor González constitute the perfect environment to conduct this project. The main factors being the outstanding research conditions, the strong
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Construction wood markets in four African towns - competing demands for renewable natural resources in the context of rapid urbanisation' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

The main objectives are to:* Examine the patterns of demand for construction wood in fast growing African cities.* Establish the structure and dynamics of construction wood markets, the wood supply networks and the agents involved.* Assess the sustainability of current patterns of exploitation of wood for urban markets.* Examine the way in which government environmental policies interact with fiscal and other policies and affect the agents in construction wood networks.* Assess the ecological, economic and policy circumstances under which tree growing for construction wood becomes profitable policies that encourage its growth.* Identify circumstances and policies which both promote the sustainable management of natural resources (wood) and facilitate the provision of affordable building materials to rapidly urbanising areas.Expected OutcomeThe work carried out in this project should provide an understanding of construction wood markets, networks and the agents involved in them. This will provide a basis for the critique of the efficacy of existing policies (environmental, forestry, construction, urban, housing, etc.) in their regulation of agents' behaviour and in providing incentives to promote sustainable development. The project should contribute to providing a sound basis for recommendations to the policy community on how to intervene effectively to achieve critical development objectives including the more rational use of forest resources, protection of endangered environments, stimulation of tree planting and improved access to affordable building materials. When dealing with policy recommendations the research will provide information on the likely distribution of policy impacts; thus it is implicitly recognised that policy inevitably creates 'winners' and 'loser
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Energy landscapes of soft matter: From super-cooled liquids to liquid crystals' under Sixth Framework.

assistant: **Concept**

This proposal aims at understanding thermodynamics and dynamics of soft condensed matter in terms of the underlying potential energy landscape (PEL). We are particularly interested in supercooled liquids and thermotropic liquid crystals, the latter being known to display rich phase behaviour.Recent studies have revealed marked similarities in the dynamics between supercooled liquids and thermotropic liquid crystals, despite their diverse physical nature. Discovering a general relation between the onset of slow dynamics and the temperature-dependent exploration of the underlying PEL would be of great interest.We aim to characterize a unifying landscape mechanism for slow dynamics in soft matter. To understand the fundamental basis for the observed similarities, we propose to characterize the PEL of a variety of model systems in terms of local minima and the transition states that connect them. Thermodynamic and dynamic properties will then be computed through simulations using methods developed in the host group.The project will therefore combine the expertise of the applicant in soft matter with that in the energy landscape formalism of the host. A key feature of the proposal will be the treatment of orientational degrees of freedom and their interplay with translational coordinates.The interdisciplinary nature of the proposal, with applications to diverse physical systems, would appeal to a wide scientific community. Soft condensed matter is ubiquitous in nature and finds a wide range of application s, from household use to the development of cutting-edge technologies.Further development of fundamental knowledge of the dynamics of these systems would certainly be helpful for engineering these applications (for example, the use of liquid crystals in displays). Moreover,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Control of the blood-brain barrier integrity during seizures via the ATP-gated P2X7 receptor' in the context of a Horizon 2020 call.

assistant: **Objectives**

Epilepsy is the most common chronic neurological disorder, affecting ~50 million people. Major challenges in epilepsy include non-responsiveness to treatment and no effect on disease progression provided by anti-epileptic drugs. Over the past decade, particular attention has been paid to dysfunction of cerebral vasculature and inflammatory processes as important players in epileptogenic processes, with a specific emphasis on failure of the blood–brain barrier (BBB). The BBB is a complex cellular network forming a continuous cellular barrier separating the CNS from the bloodstream. A functional BBB is crucial in maintaining brain homeostasis and to prevent the entry of toxic compounds and immune cells into the CNS. During pathology, however, the permeability of the BBB may increase with the resulting entry into the CNS of blood-borne molecules and cells. Leakage of the BBB is one of the earliest characteristic pathophysiological disturbances following status epilepticus and may play an important role in the development of epilepsy. Consequently, drugs targeting BBB function may represent novel treatment strategies in epilepsy. The purinergic ATP-gated P2X7 receptor has gained much attention recently as novel target in the treatment of epilepsy. Expressed on all cell types in the CNS including endothelial cells, P2X7 has been associated with numerous damaging processes pertinent to epileptogenesis, such as inflammation and opening of the BBB. ATP and the P2X7 downstream target Interleukin-1β contribute to the disruption of the BBB and P2X7 antagonism protects against BBB disruption during intracerebral hemorrhage. To date, however, we do not know whether seizure-induced changes of the BBB are dependent on P2X7 signaling, and whether this process can be targeted. By using
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Transnationality at Large: The Transnational Dimension of Hispanic Culture in the 20th and 21st Centuries' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Transnationality is a paradigm that currently impacts heavily on the Humanities. Surprisingly, Hispanic culture has not yet been of primary concern to transnational studies, even though, covering a very wide geo-cultural area , the case for its inclusion as a case study is undeniable. The research centres collaborating in this application share a clear interest in transnationality, and specialize in different areas of contemporary Hispanic culture (Spain, Latin America, Hispanic migrant culture). A structured plan of mobility, spanning four years, will involve an ambitious collective research programme that addresses Hispanic transnationality at large, focusing on strategically chosen cultural areas, and maximizing complementary knowledge and expertise in the cultural field (literature, photography, film). Given that Europe is a transnational project heavily relying on cultural affinities, this project is likely to contribute to reflection on complex European problems in an era of accelerated globalization, such as migration, cultural memory, and multiple citizenship.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Personalised Mechanobiological Models to Predict Tumour Growth and Anti-Cancer Drug Penetration' (MechanoGAP) targeting Horizon Europe.

assistant: **Abstract**

Personalised cancer medicine presents an exciting frontier in healthcare that tailors disease mitigation and intervention to an individual patient. However, existing technologies fail to leverage the physical forces that underpin stress-dependent tumour growth and the subsequent evolution of biomechanical resistance to anti-cancer drugs. Furthermore, the fundamental mechanisms governing such force-sensitivity have yet to be uncovered; this deficiency in scientific understanding of the active biomechanical behaviour of tumours and control of drug penetration has hindered the progression of anti-cancer therapy.   In this project, an advanced computational modelling framework will first be developed to uncover the mechanisms underlying stress-dependent cell and tissue growth, coupling the thermodynamics of cellular volume control with active force generation and intracellular transport. Novel experimental analysis of 3D tumour spheroid growth and single cell biomechanics will reinforce the framework to gain a new understanding of how mechanical loading can prevent tumour cell division and the role of intracellular exchange in multi-cellular growth control. The models will then be extended to determine the role of growth-induced stress and cell compaction in restricting drug penetration, and whether this can be mitigated by promoting intracellular drug perfusion. Finally, integrated patient-derived computational and tumour organoid models will be developed for prediction of growth and emergent biomechanical resistance to anti-cancer drugs, motivating model-led mechanobiological therapy in an animal model of breast cancer.    The overarching objective of this ground-breaking project is to pioneer a personalised healthcare framework for prediction of mechanically-regulated ca
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'European Training Network for the sustainable, zero-waste valorisation of (critical) metal containing industrial process residues' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Unlike China, Russia or South Africa, the EU-28 Member States are not in the fortunate position of having vast, easily accessible ore deposits containing valuable metals. However, Europe does have large quantities of secondary industrial residues (tailings, sludges, slags and ashes) that contain sig¬nificant concentrations of both critical and economically important metals. The Euro¬pean Training Network for the Sustainable, zero-waste valorisation of critical-metal-containing industrial process residues (SOCRATES) targets ground-breaking metallurgical processes, incl. plasma-, bio-, solvo-, electro- and ionometallurgy, that can be integrated into environmentally friendly, zero-waste valorisation flow sheets. By unlocking the potential of these secondary raw materials, SOCRATES contributes to a more diversified and sustainable supply chain for critical metals (cf. Priority area 3 in EC Circular Economy Action Plan; COM(2015)614/2). The SOCRATES consortium brings together all the relevant stakeholders along the value chain, from metal extraction, to metal recovery, and to residual matrix valorisation in added-value applications, such as supplementary cementitious materials, inorganic polymers and catalysts. To maximise applicability, SOCRATES has selected four commonly available and chemically complementary residue families: (1) flotation tailings from primary Cu production, (2) Fe-rich sludges from Zn production, (3) fayalitic slags from non-ferrous metallurgy, and (4) bottom ashes from incineration plants. As a basis for a concerted effort to strengthen the EU’s critical-metal supply chain for Ge, In, Ga and Sb, SOCRATES trains 15 early-stage researchers (ESRs) in technological innovation: metal extraction (WP1), metal recovery (WP2), residual matrix valorisation (WP3)