RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Regulation of protein secretion by the signal recognition particle and its receptor' (1994-1998) under Fourth Framework.

assistant: **Objectives**

The proposed network comprises nine laboratories in seven European countries. All participating laboratories are already actively engaged in ribonucleoprotein complex which mediates targeting of secretory proteins research on structural and/or functional aspects of the signal recognition to the translocation apparatus in the inner membrane of bacteria or the endoplasmic reticulum membrane of eukaryotes. We propose to combine particle with expertise ranging from cell biology through biochemistry to structural and functional methods on both eukaryotic (mammalian, X-ray crystallography. This multi-disciplinary context will be an ideal chlroplast) and prokaryotic (E. coli and Mycoplasma) systems in a framework for the training of the nine post-doctoral fellows which it is multi-disciplinary approach to advance understanding of the mechanism and planned to recruit (one for each network member). In each case, the new recruits will join laboratories in which the participation of other young regulation of this important cellular process. In a field which is almost devoid of high resolution structural information, a major objective will scientists (PhD students, post-doctoral fellows) is high. Furthermore, be structure determination of components of the signal recognition several of the network laboratories are very recently established independent groups ( including one from a less favoured region). These particle and its receptor.  We will initially focus the structural work on groups will particularly benefit from participation in the network which (a) the signal sequence binding protein SRP54 and its bacterial also includes more senior groups, well established in the field of protein homologues, secretion.  (b) the Alu-domain of mammalian SRP which is responsible for elongat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Sustainable oceans : our collective responsibility, our common interest. Building on real-life knowledge  knowledge systems for developing interactive and mutual learning media'.

assistant: **Objectives**

The project will develop well-targeted and sound communication material that raises awareness on our (individual and collective) responsibility and interest in ensuring the sustainability of the ocean and of its ecosystems. The project builds on critical assessments of: (1) existing communication strategies, material and governance that focuses on the ocean; (2) the values, perceptions and understanding of the state, functioning and role of the ocean by different types of stakeholders and of the wider public; (3) the (scientific) knowledge that exist on the ocean-human relationship, in particular in terms of ecosystem services that can be delivered by ocean ecosystems and support (future) development opportunities and blue growth and of pressures that are imposed on the oceans. These critical assessments will help identifying priority target groups with key responsibilities and interests in the state of our oceans - today and in the future. Within a participatory process involving the stakeholders of the knowledge creation &  sharing system from four European marine regions  (Baltic Sea, Mediterranean Sea, Northern Sea and Atlantic _ including in its transatlantic dimension), and building on the scientific knowledge-base established and on project-dedicated IT strucure/platform, the project will then develop and test under real conditions innovative communication tools. Key principles guiding this development will be interactivity, mutual learning, creativity and entertainment. Finally, specific activities will be performed for ensuring proposed communication tools are made accessible and available to their future users in Europe but also elswhere.


**Keywords:** sustainable ocean, collective and individual responsible and interest, interactivity, mutual learning, Euro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Identification of new molecules able to bypass the cell wall compensatory pathways in the pathogenic fungus Aspergillus fumigatus' (CELLWALLPATH), addressing dissemination and exploitation.

assistant: **Impact**

Aspergillus fumigatus is the most important air-borne fungal pathogen, causing severe infections with invasive growth in immunocompromised patients. For growth in all habitats, the fungus needs to be able to sense environmental stimuli and to transduce signals via specific signalling cascades. Calmodulin/calcineurin, Ras/cAMP, mTOR and general Mitogen-activated protein kinase (MAPK) signalling pathways are involved in the regulation of various cellular responses in eukaryotes. Previous studies revealed that the central core of the MAPK cell wall integrity signalling pathway in A. fumigatus is composed of three protein kinases. Deletion of these genes resulted in severe sensitivity of the mutants against cell wall-disturbing compounds and drastic alterations of the fungal morphology. Nevertheless, the mutants were still virulent in a murine infection model. Even more, therapeutic treatment with medical commercial cell wall-acting compounds, like echinocandins and azoles, did not result in effective treatment against aspergillosis, indicating the importance of cell wall assembling pathways compensating the inhibition caused by cell wall-disturbing compounds. Protein kinase activation requires phosphorylation. This process is reversible even in the continued presence of activating stimuli. The importance of protein phosphatases for signalling pathways and cross talk interactions is emerging. Ontology classification analysis revealed that the A. fumigatus genome contains 24 genes coding for putative protein phosphatases. A comprehensive and extensive study on protein phosphatases in filamentous fungi has never been attempted so far. Here, we propose to study protein phosphatase families in A. fumigatus. Mutant strains will be used to investigate cell wall compensatory pathw
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Structural and biochemical basis of protein amyloid evolution'.

assistant: **Objectives**

Protein misfolding and aggregation into amyloid fibrils is a hallmark of serious diseases such as Alzheimer´s, Familial Amyloidotic Polyneuropathy (FAP) and atherosclerosis. Amyloid fibrils can also be biologically functional. Bacterial and fungal amyloids are proposed to form a prominent protein fold early in evolution. It is unclear why many different proteins, which often assume stable functional quaternary structure under normal conditions, can convert into a common β-sheet rich amyloid aggregate. An important unanswered question is whether the molecular mechanisms of amyloid formation have been conserved in evolution. We will characterize these mechanisms using two very different proteins involved in amyloid diseases: apolipoprotein A-I (apoA-I), a helical protein that is important in atherosclerosis and familial amyloidosis, and transthyretin (TTR), a beta-sheet protein that forms amyloid in FAP. We will explore in detail the novel molecular mechanism of amyloid formation by human apoA-I , which will help design a strategy to block this process. We will further characterize amyloid formation in evolutionary diverse species using fish TTR as a model protein that, we previously showed, forms amyloid. Fish are the most biodiverse group of vertebrates that can adapt to broad range of external conditions; hence, they are particularly suitable to study the adaptation of protein structure/function. TTR amyloid  formation will be characterized in two evolutionary distinct piscine species with different adaptation mechanisms: a modern Actinopterygii (sea bream) and an ancient Agnatha (lamprey). The role of sea bream TTR N-terminus, previously proposed to be important in amyloid formation, will be investigated and compared with human TTR. The results will provide sharper in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Safety Assessment of Non-Electric uses of nuclear energy' under Horizon Europe.

assistant: **Concept**

Safety Assessment of Non-Electric uses of nuclear energy (SANE) project investigates the potential of non-electric usage of nuclear energy, the safety aspects of reactors designed for non-electric use as well as the safety implications of the end use. As many of the applications are novel, their use needs to be properly communicated to various stakeholders, and for this the project includes work on risk communication.Non-electric uses are identified in EU SMR pre-Partnership as one of the high level R&D needs, and the understanding of the potential applications and their limitations as well as the challenges in integration of nuclear energy to end use were seen as important issues to be studied. Non-electric uses will be an important way to diversify the income streams of nuclear plants, as the electricity production will become more and more competitive. Nuclear has unique advantages in non-electric uses as it can produce lot of energy locally for large local uses.SANE aims to review potential future uses of nuclear energy in order to facilitate their implementation in the near future. This project aims to provide information for both industrial applications retrofitted to operating nuclear power plants, as well as for novel reactors dedicated for non-electric uses. Information needs for appropriate risk communication is studied with case studies in several countries, and a specific study on communications during abnormal situations is done based on the events that transpired in Ukraine during Russia's invasion.


**Keywords:** Nuclear energy, hydrogen, non-electric uses, process heat, safety, risk communication
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Politics and Practices of Listening in Mao era People's Republic of China.' (PPLMEC) targeting Horizon Europe.

assistant: **Abstract**

This research, drawing on state archives, private memoirs, and literary materials provides the first dedicated history ofauditory cultures of the People's Republic of China (PRC). By focusing on the act of listening across three pivotal andtransitional moments of PRC history and at three levels of state, locality, and individual, it explores the role of sound fromthree perspectives: as a tool of nation-building deployed by the state; as a medium through which the Chinese revolutionwas experienced at an individual level; and in the contestation between these two domains as the soundscape became asite of contention and negotiation between the state and the citizen. The researcher's background in social, cultural, andpolitical history of the Mao era, along with the supervisor's expertise on Chinese modern history and experience researchingthe history of sound and broadcasting in the Republican Era (1911-1949), will be deployed to provide the ideal backgroundfor this innovative but delimited project. The key questions asked will be threefold: 1) How, and under what understanding ofthe act of listening, did the state deploy sound as a political and social tool in the People’s Republic of China? 2) How weresuch state initiatives deployed at the local level and with what results? 3) How was the act of listening among individualstransformed in response to state initiatives? The resulting interdisciplinary research will expand the field of global soundstudiesbeyond its current Eurocentrism, apply Sound-Studies to China for the first in-depth and long term empirical study,and enhance European knowledge of modern China.


**Keywords:** China, Sound Studies, Maoism
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Open Trusted Computing' under Sixth Framework.

assistant: **Concept**

In today's networked environment, the well known lack of platform security has given rise to waves of successful attacks, resulting in severe damages to enterprises and potential failure of critical infrastructures.<br/>Building on the cost-efficient and widely deployed ¿Trusted Platform Module¿ (TPM) specified by the Trusted Computing Group (TCG) and the new generation of x86 CPUs from Intel and AMD, we will define and implement an open Trusted Computing framework.<br/>The architecture is based on security mechanisms provided by low level operating system layers with isolation properties and interfaces to Trusted Computing hardware. These layers allow to leverage enhanced trust and security properties of the platform for standard operating systems, middleware, and applications.<br/>The suggested architecture is applicable to a wide range of platform types, e.g. servers, GRID technology, mobile phones and industrial automation. It provides basic building blocks for complex, distributed scenarios with inherent, multilateral trust and security capabilities.<br/>To enable maximum community benefit, project results will be integrated in and distributed as Open Source software, supporting Linux in particular.Should the proposal be successful, first Open Trusted Computing prototypes could be available around the time when proprietary Trusted Computing operating systems and solutions are expected to hit the market.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Visible-light-driven CO2 reduction to SynGas using water as electron and proton donor over a Z-scheme photoelectrochemical cell' under Seventh Framework.

assistant: **Concept**

The finite petroleum feedstock and the increased concentration of the greenhouse gas CO2 in the atmosphere have led to the concept of renewable CO2 utilization. The use of CO2 as a starting material for the chemical industry would not only relieve environmental pressures on our society, but it is also vastly abundant; with approximately 300 billion tons, CO2 is the most abundant carbon source in the Earth’s atmosphere. Therefore, a driver for investment in CO2 utilization will be the ability to maintain security in the supply of sustainable fuels and commodity chemicals that have traditionally relied on non-renewable petrochemical sources.Currently, approximately 75% of the world’s energy demand is covered by fuels, while only 25% by electricity. Photovoltaics, wind and other renewable energy sources can only cover the electricity demand. There is currently no viable solution to produce fuels on a global scale in developed nations in a post-fossil era. This ambitious and innovative project tackles the challenge to produce renewable fuels through the conversion of CO2 to SynGas (CO + H2), which can be subsequently transformed into liquid hydrocarbons through the known Fischer-Tropsch process, and it would address the three quarters of the global energy demand.Conventional heterogeneous catalysis, electrocatalysis and photocatalysis are presently the most commonly used methods of reducing CO2 to useful products. All of these techniques require an energetic input (thermal energy, electricity and light). The sun delivers solar energy to the Earth with a power of >120,000 TW, which greatly exceeds the current annual global energy consumption of ~15 TW, and is thus the most sustainable source of energy available to humanity.The ultimate goal of this project is converting CO2
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The Teacher of Righteousness and Religious Experience in the Dead Sea Scrolls' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The proposed project is a comprehensive assessment of the evidence for the figure known as the ‘Teacher of Righteousness’ in the Dead Sea Scrolls discovered at Khirbet Qumran. It is the first such study based on the entirety of the corpus which has only recently become completely accessible. The project will construct a model for how the memory of the Teacher operated within the ancient socio-religious context of communities behind the Scrolls and provide answers to questions previously overlooked within a strictly historical-critical approach.The methodological approach used for this study is based on recent research on the body and emotion which crosses multiple disciplinary boundaries and applies them to key texts that mention the Teacher of Righteousness. Traditional historical-critical methods grounded in both literary and historical concerns are complemented by rhetorical approaches and recent scholarship on the body and its experiences. Key fields of study include theories of embodiment and subjectivity from post-structuralism, performance studies, and ritual studies. A critical component of the approach taken in this project builds on the social and biological processes of emotion which allow for the recovery of a bio-cultural understanding of the experience of religion at this time. While emotion’s role in the construction and reconstruction of memory has been long acknowledged, this study examines how the strategic arousal of affect generated by texts that mention the Teacher serves to reinvigorate and intensify his memory among his followers. This innovative study is part of an emerging field of research known as ‘Religious Experience’ that seeks to recover the phenomenal experience of religion.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Development of 4k compatible LCOS micro-display for D-cinema and simulation applications'.

assistant: **Objectives**

Liquid Crystal on Silicon (LCOS) combines two very well-known technologies, namely the IC/CMOS and the Liquid Crystal (LC) technologies. As both of these are very mature, it is obvious that LCOS has a huge potential for very high-end applications, more than any other (projection) technology.The aim of the FORK project is the development of a LCOS microdisplay device for very diverse applications in simulation, medical imaging, control rooms and digital cinema. These applications require or benefit from very high pixel counts, high contrast ratio's, very high light fluxes and very good colour and brightness uniformity, analog pixel addressing and high response times.While some non-European suppliers have announced microdisplay devices for the applications mentioned above, we are not aware of any devices which meet all of these criteria.In order to meet all of these criteria, additional challenging research is needed in the field of LCOS backplane and driver design, LCOS backplane processing, IC (Integrated Circuit) stitching, new or improved Liquid Crystal (LC) mixtures, LC assembly and thermal design and packaging.The FORK project consortium gathers European competence centres, each having expertise in one or more of the technology fields mentioned above. This consortium has drawn an ambitious though realistic workplan in which the targeted project objectives can be reached successfully.The European display and semiconductor industry is under strong international competition, mainly from greater China and other Asian countries. A possible way to escape from the cost pressure is to differentiate by specialties and added-value features generated by innovation, IP and know-how. These values will be generated with the objectives of the FORK project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how '6th conference of european foundation for plant pathology: resistance in plant pathology' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

On the 4th Meeting Board in Bonn, 1996, the Czech Society for Plant Pathology (CSPP) received preference before France society for Plant Pathology to organize the 6th Conference EFPP 2002 devoted to Resistance in Plant Pathology. Four main sessions are foreseen in order to bring up the state of the art in the study of host-pathogen interactions and plant resistance to pathogens as well as new control strategies preserving the environment and improving the safety. The Conference also aims the implementation of disease resistance in support Common Agricultural Policy in the context of sustainable agriculture. The large expected participants audience (ca 300 people from 20 EU+CC and 100 from NIS+ BC+ inv. speakers, chairs) gives the opportunity to organize panel sessions on European natural resources of resistance, on conf. achievements for breeding practice. A book of abstracts of the Conference will allow the information of scientists.