RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Understanding aneuploidy tolerance in cancer by studying early embryogenesis'.

assistant: **Innovation**

Can we study complex cancer biology by using a more predictable and structured model of embryogenesis? Many of the hallmarks of cancer biology are shared with the biology of embryos: sustained proliferation, migratory behavior, angiogenesis, immune system suppression, and in my opinion the most fascinating: the tolerance of genome instability.Chromosome segregation errors and resulting aneuploidy are an important source of intratumor heterogeneity, therapy resistance, and metastasis in cancer. On the other hand, aneuploidy is detrimental during development. However, despite the detrimental effects of aneuploidy, most human pre-implantation embryos are mosaics of euploid and aneuploid cells, and the proportion of aneuploid cells is progressively depleted from embryos as the cell differentiation progresses from the blastocyst stage onwards. Therefore, could it be the undifferentiated state or de-differentiation of cells that might play a role in aneuploidy tolerance? Here I plan to study and compare aneuploidy tolerance during embryogenesis and in cancer, and investigate if differentiation and de-differentiation of cells play a role in this phenomenon. In the suggested experiments I will examine cells' response to chromosome segregation errors in human embryonic stem cell gastruloids (hESC),  colorectal cancer organoids (CC), and normal colon organoids (NC) after aneuploidy induction with Msp1 inhibitor (+/- CENP-E inhibitors). Specifically, I will assess the cell proliferation rate, cell cycle progression and apoptosis with live-cell imaging, as well as transcriptional profiles using single-cell RNA-seq. Next, I will assess the same phenotypes after the addition of different growth factors that change the differentiation state of the cells.  Ultimately, I would like to f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'ONO - THE URBAN UTILITY VEHICLE FOR TODAY AND TOMORROW’S DRIVING'.

assistant: **Innovation**

In Europe alone, there are over 500.000 delivery trucks roaming our streets and producing 6 million tons of CO2 each year. They are also a primary cause for traffic jams in most major cities. These vehicles are extremely harmful, not only to the environment, but also to the quality of life in cities. Air and noise pollution, road congestion and lack of space are problems seriously affecting big cities. Tretbox GmbH is introducing a new category of electric vehicle – called ONO - which is not only better for cities, but also offers reduced operational costs for logistics operators and is designed for demand growth in today’s and tomorrow's cities: we replace the gasoline trucks with a combination of city depots and a new type of electric cargo bicycle. We allow operators flexibility in the capacity of the vehicle according to changing workloads. For the drivers, we offer the ergonomics, the comfort and safety they would hope for. ONO offers logistics market customers the option to switch from their existing combustion engine trucks to modern electric cargo bicycles. By doing so, they save money, time and gain flexibility while enhancing their brand perception. The logistics market is growing exponentially, yet still employing antiquated delivery methods not adapted to their needs. Tretbox GmbH, a German company founded in 2016 and based in Berlin, is solving the aforementioned problems thanks to a talented team of designers and engineers, led by our co-founder, former Head of Design for the Volkswagen Group.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The Impacts of Climate Protection on Agricultural Productivity and Food Security' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

The European Union's goal of achieving climate neutrality by 2050 is crucial for transitioning to a low-carbon economy. However, ambitious reductions in greenhouse gas emissions may lead to unintended consequences, notably from current EU policies. On one hand, increasing food production for Zero Hunger (SDG 2) can escalate greenhouse gas emissions, responsible for about 34% of total anthropogenic emissions. Predictably, direct carbon emissions from agriculture will rise in the coming decade. Yet, mitigating these emissions, especially in the short term, may reduce production and raise food prices, potentially limiting access, especially in food-insecure regions. This could lead to increased poverty and stunting. Balancing emissions reduction with agricultural productivity and global food security is a critical challenge.To avoid unintended negative consequences and optimize climate protection policy benefits, interactions between different objectives must be considered in policy formulation. The CliAgroSec project aims to create a framework exploring synergies between agricultural productivity, food security, and climate protection objectives, while acknowledging trade-offs in multi-objective policy development. This involves crafting comprehensive ""sustainable policies"" encompassing environmental, economic, and social dimensions.The project has three specific objectives:Elaborate on potential synergies and trade-offs between climate protection policies, agricultural productivity, and food security. Propose a theoretical framework to identify negative externalities of climate protection policies within global climate agreements.Develop a comprehensive integrated empirical model, combining a global Computable General Equilibrium (CGE) model with an agri-environmental
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Symbiotic Mind Computer Interaction for Information Seeking' (MindSee) targeting Seventh Framework.

assistant: **Abstract**

While real time analysis of user states based on signals from the brain and peripheral physiology have made progress (as separate branches of research), the possibility to predict intentions and infer implicit user variables is still a grand challenge in real-world applications. As a novel approach, MindSee proposes to fuse EEG as a main sensor with peripheral physiological sensors (EDR, fEMG, eye gaze and pupillometry) and context information for an unobtrusive acquisition of implicit measures of perception, cognition and emotions. Real-time estimates of these hidden user states will be exploited to complement keyboard and gestural input exemplary in the real-world application of scientific literature search where the information exploration of the user is guided by a co-adaptation with the computer. The proposed Symbiotic Information Seeking System will provide a wide range of visualization resources adapting information retrieved and its relevance, cognitive ergonomic complexity, and aesthetic aspects.For the target application of scientific literature search, MindSee builds upon a cutting-edge retrieval system that has access to 50 million documents from the main scientific databases. MindSee will be developed in an iterative approach with three full cycles of implementation and evaluation of increasingly complex symbiotic interactions in information seeking. The iterative evaluation of MindSee technology and validation of underlying methods will be done in realistic user experiments with user groups of different skills and areas.The MindSee project will develop a new symbiotic information retrieval system capable of more than doubling the performance of information seeking in realistic tasks, compared to mainstream tools. MindSee symbiotic interaction will deliver
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Use flexible Tube Micro Plasma (FµTP) for Lipidomics'.

assistant: **Concept**

Cancer is the leading cause of death in economically developed countries and the second leading cause of death in developing countries. In 2015, over 8.8 million people died of cancer worldwide and the numbers are expected to rise above 13 million in 2030 . As a consequence, development of non-invasive, fast and robust methods to detect different types of cancer in an early stage are timely. BIOplasma addresses the essential need for analytical tools that permit the diagnosis of biological tissues. A novel analytical strategy based on the Liquid Chromatography/Mass Spectrometry (LC-MS) using flexible Tube Micro Plasma (FµTP) as ionization source for the identification and quantification of several lipid biomarkers in body fluids is proposed


**Keywords:** Lipidomic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Optimal power production and management for water mill restoration' in the context of a Fifth Framework call.

assistant: **Objectives**

The project consists of SME's from Ireland and Finland leading a European research project in the development of a technologically advanced power management system for restored water mills. A successful research conclusion will make the restoration of abandoned water mills feasible and economic. This will enable restoration of derelict sites in rural areas and provide renewable energy. It will also create jobs in areas of high unemployment through improved competitiveness of EU SME's in a new and sustainable industry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'European Legitimacy in Governing through Hard Times: the role of European Networks' in the context of a Horizon 2020 call.

assistant: **Objectives**

ENLIGHTEN responds to the first part of the EURO-4 call on “The future of European integration - 'More Europe – less Europe?'” by bringing together an interdisciplinary  ‘next generation’ research team that integrates insights from Comparative Political Economy, European Studies, International Political Economy, and Sociology. ENLIGHTEN answers the call by focusing on how European modes of governance respond to ‘fast-burning’ and ‘slow-burning’ crises. These types of crises differ in how they affect the legitimacy of European input, output, and throughput processes in established and emergent modes of governance. In fast-burning crises interests are quickly formed and ideational and resource battles ensue over how to coordinate policy ideas, what institutions should be engaged, and communicating these changes to the public. Networks in fast crises are composed of defined groups seeking to protect or carve out their interests. In slow-burning crises interests are less obvious and the key task is often how to define the issues involved and who should address the problem. Here networks are commonly composed of experts who battle over how issues should be defined, as well as the boundaries on how coordinative and communicative discourses are articulated. Both fast- and slow-burning crises must be addressed by European modes of governance, with serious implications for the legitimacy and efficiency of the European project. Both raise political, social, and economic sensitivities that are transforming democratic politics in Europe. ENLIGHTEN addresses these themes through a series of linked cases that speak directly to the legitimacy and efficiency of European modes of governance.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Small Molecule Activation by Main-Group Compounds' (SMAC-MC) under Horizon 2020.

assistant: **Objectives**

Many basic chemical processes involve the activation of small unreactive molecules, such as hydrogen, nitrogen, ammonia, water and carbon dioxide, by transition-metal-based catalysts or by enzymes. This proposal focusses on the interesting and recently observed possibility to perform similar transformations with main-group compounds that consist entirely of cheap earth-abundant elements. The proposed research is split into four work packages of which the first investigates the mechanisms by which different main-group singlet diradicaloids activate small molecules and how their reactivity correlates with their radical character. The second work package focusses on small molecule activation using main-group metalloid clusters, a new emerging field that we have recently pioneered, and compares the reactivity determined for main-group species with that known for related transition-metal clusters. Investigations in the third work package concentrate on the electrochemical reduction of carbon dioxide and on the possibility to lower the required overpotential with frustrated Lewis pairs that readily form adducts with small molecules. The fourth work package revolves around activating small molecules by diborenes and, in particular, observing novel reactivity in situ, that is, before the reactive diborene is trapped with a suitable Lewis base. Considered as a whole, the planned initiatives will enable significant breakthroughs in the design of novel main-group element based compounds for the activation of small molecules. The research is not only of fundamental scientific importance but also of potential practical value as many main-group systems, such as frustrated Lewis pairs, are currently being examined as novel catalysts. An ERC consolidator grant would significantly stren
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project '#NitRecercat: La Nit Europea de la Recerca""' (NitRecerCat) under Horizon Europe.

assistant: **Objectives**

The Catalan European Researchers Night (#NitRecerCat) project consists in a two years proposal for 2022 and 2023 centered on two main activities: The European Researchers Night (ERN) and Researchers at Schools (R@S). The well-known ERN will be held on September 30th 2022 and 29th 2023. During these two years, eight different partners will bring research and researcher closer to more than 30000 people and 10000. A part of ERN, the present proposal also includes the Researchers at Schools (R@S), which adds a much better and longer interaction of pupils with the research from the Catalan institutions. 15 schools (and near 4000 students) will become #NitEduCat Schools, with two-years of stable collaboration between a team of researchers and the schools (primary and secondary). The will focus on making the general public aware about the present mission-oriented program of European Commission (EU), mainly in the idea of how Researchers can help to change the world (Researchers for Change). #NitRecerCat is divided in two main activities spread throughout the Catalan territory:oCatalan European Researchers Night (Nit Europea de la Recerca, ERN)    La Recerca va a lEscola During Friday morning, researchers are going to schools to show their research and vice versa.    La Nit Catalana de la Recerca  Friday evening/night main activity. Women in Science based on the exhibition Cientfiques Catalanes 2.0 will be shown in all the locations and venues (online).   Esopegat amb la Recerca  During Saturday morning, research will be found in everyday locations, from markets, to museums, malls, etc, oResearchers at School  (R@S)   NitEduCat Schools  Going beyond single dissemination activities, this part of the project aims to develop 15- medium-long-term projects that promote stable collab
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Women’s Plague Writing in Early Modern England' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

In a time when high-profile outbreaks such as zika and ebola frequently make news headlines, the proposed research project, ‘Women’s Plague Writing in Early Modern England’, provides an opportunity to interrogate how we interpret medical writing, who talks about medical problems and how gender becomes entangled in outbreaks by looking to the past. ‘Women’s Plague Writing in Early Modern England’ will undertake a survey and analysis of women’s plague writing in England from 1550 to 1700. A three-year Global Fellowship project with a two-year outgoing phase at the University of Toronto (UofT) and incoming phase at Queen’s University Belfast (QUB), the research action takes an interdisciplinary approach to women’s plague writing across the early modern period in England. The research programme explores the medical humanities through the lens of literature in its historical context. This project will change the canon of plague writing, which has hitherto focused on male-authored texts. Moving from the single outbreak focus seen in my first monograph, The Literary Culture of Plague in Early Modern England (forthcoming with Palgrave Macmillan), the outcome of the project makes the significant leap to studying a period of plague writing, a bigger-scale picture, with a broad chronology that captures major plague outbreaks in 1592, 1603, 1625, 1630, 1636 and 1665. The project encapsulates a full-period picture of women’s interactions with plague and medicine and the corresponding gendering of plague writing. It will examine how women discuss the disease and how this differs from male-authored texts. It will ask how the medium chosen for publishing a text, print or manuscript, impacted how women discussed the disease. It will investigate how women’s understanding of plague was ge
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Integrating the processes involved in the production of creosoted utility poles' (WOODPOLE) targeting Fourth Framework.

assistant: **Abstract**

The overall objective is to produce high quality utility poles treated with the minimum quantity of creosote necessary to achieve the required service life. The work is divided into tasks representing different aspects of the forestry chain in pole production. Task 1: Provision of high quality decay free dry poles in a suitable condition to subsequently achieve optimised treatment. This will involve identifying the most environmentally safe and effective way of delivering permeable poles free of pre-treatment decay which is known to occur in poles air dried for long periods in order to establish 'best practice' for white pole production. Task 2: Provision of the biological test data required during the next five years on the new more environmentally friendly range of creosotes to satisfy EN 533-1 efficacy requirements and thus support continued use of t'nis type of product.A secondary objective is to suggest modifications to the existing European Standards (EN 113 and ENV 807) to make them suitable for testing creosote type products through investigation of alternative methods of pre-conditioning prior to laboratory test and selection of appropriate strains of test fungi. Task 3: Determination of the nature and point in time of failure of creosoted poles in service and in existing field trials and relate these findings to the original retentions in order to determine the multiplication factor needed to modify the critical value determined in biological tests to establish the minimum retentions necessary for particular required service lives. Task 4: Determination of the treatment parameters necessary to treat the high quality poles delivered by Task 1 to achieve the minimum retentions determined in Tasks 2 and 3 whilst minimising side effects such as bleeding. Additiona