RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Q-Room – Quintetto’s Holographic Telepresence Room' under Horizon 2020.

assistant: **Concept**

Telepresence? With holographic telepresence it becomes reality. A new system, just showcased in Italy, that allows interaction between physically distant individuals, in a realistic and natural way. The project directed by IT Company Quintetto, in cooperation with the Italian Research Council (CNR), opens interesting possibilities of application in areas where real and direct interaction between users is important. These scenarios are certainly the banking and public offices world, where telepresence could revolutionize contacts, changing the way of delivering services from the traditional, physical branch to a new, virtual one. Telepresence can become a tool to improve the territorial coverage of banks, providing essential services to citizens in an economic, organizational model. For the first time, this system brings a very realistic, 3D interaction to the market, at an affordable cost, simply using an ordinary internet connection. The user has the perception of being seated in front of a real operator who guides him through the process simply and quickly, from product selection to contract signing by physical printing of the document. This is just an example of how technological innovation can radically transform the user experience, shaping services based on evolving needs and expectations. In order to bring the product to the later stage of development to hit the market, Quintetto would like to assess the commercial feasibility of the Q-Room. The objective of the Phase 1 of the innovation project is a business plan outlining the economic strategy: market analysis of the state of the art in the eligible market and an investigation of main competitors will accomplish the feasibility report. The business plan will also define a successful marketing and commercial str
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Nanobody-targeted photodynamic therapy to kill cancer' (KILLCANCER), addressing dissemination and exploitation.

assistant: **Impact**

Current cancer therapies often fail to cure patients. Ideally, therapy should locally eradicate cancer and should be capable of inducing long term protection, through activation of the immune system. Photodynamic therapy (PDT) is a treatment approach in which cancer cells are killed with compounds, named photosensitizers that are activated locally through light exposure. Importantly, PDT eradication of cancers commonly involves the immune system. However, current photosensitizers lack cancer specificity, which limits therapeutic efficacy and prolongs photosensitivity in patients.Recently, I have developed an improved version of targeted PDT that uses very small antibodies i.e. nanobodies that distribute homogenously, bind rapidly and specifically to cancer cells, and a photosensitizer that can be traced by optical imaging to guide the application of PDT.The aims of this proposal are to better understand and to advance nanobody-targeted PDT to ensure complete cancer eradication, and to facilitate its clinical translation. This will be achieved by:1) Exploring the increased accumulation of photosensitizer through development of novel nanobody-photosensitizer conjugates to bind to cancer cells, cancer stem cells, and endothelial cells. These combinations will be evaluated for their efficacy in mice bearing human carcinomas;2) Investigating the immune system activation to determine if, as other PDT, nanobody-targeted PDT triggers a systemic immune response, or if additional triggers are needed;3) Studying the effect of nanobody-targeted PDT in dogs entering the veterinary clinic with oral or colorectal cancers. Treatment efficacy will be evaluated by monitoring cancer regression or disappearance.The outcome of this research will scientifically advance the new field of nanob
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Organisation of a workshop to provide virologists with theoretical background and training in molecular phylogenetic analysis methods.'.

assistant: **Concept**

Molecular phylogenetic analysis is widely used by virologists to study the epidemiology and evolution of viruses. Many virologists that are using these methods lack a theoretical background and practical training often resulting in misinterpretation of results. In this workshop we will give a thorough training in the scientific background of molecular evolution, the elementary problems of molecular epidemiology and give the participants a perspective of which methods are available and what kind of information can be obtained from them. Participants will also be requested to present their own research data. In this way, trained virologists will be able to perform and evaluate molecular epidemiology, and will have contacts with other participants and with the workshop teachers to discuss the application of phylogenetic analysis for the specific epidemiological problems they encounter during their research.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Development of a novel continuous Extracellular Vesicle production system' under Horizon 2020.

assistant: **Concept**

Functional foods boosted with bioactive nutrients to enhance health and mitigating disease conditions are experiencing an amazing progress. Encapsulation is becoming an important strategy to enhance the bioavailability of poorly absorbed compounds and developing healthy foods. In this context, novel nano-scale approaches to create alternative delivery options for nutraceuticals are emerging. GreenEV aims to develop a continuous plant tissue culturing system for the manufacturing of non-mammalian nanovesicles, and exploit them for the encapsulation, release and bioavailability enhancement of selected nutraceuticals. Plants cells have been shown to physiologically release phospholipid membrane-surrounded vesicles into the apoplast and environment. These vesicles are morphologically similar to mammalian extracellular vesicles (EVs). The process that drive the vesicle formation and their release through the semi-rigid cell wall is not trivial, and will be studied in the greenEV.The experienced researcher is a plant biologist with strong background in plant tissue culturing who team-up with the Institute of Biosciences and BioResources (IBBR) with considerable expertise in EV research to realize a uniquely interdisciplinary research program. The research proposed here will realize the following concrete objectives: 1. Set-up a novel, plant-based EV production system, 2. Employ an integrated analytical pipeline for the isolation, characterization, encapsulation, uptake and toxicological profiling of plant secreted EVs. Neither of these objectives have been addressed before and both have high potential to expand the knowledge in the field and to drive the research activity towards industrialized continuous production of plant EVs. The research objectives are integrated with co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Proof-theoretic methods in algebra' (PROALG) under Seventh Framework.

assistant: **Objectives**

The goal of this project is to develop and exploit proof-theoretic methods for ordered algebraic structures. Traditionally, algebra and proof theory represent two distinct approaches within logic: the former concerned with semantic meaning and structures, the latter with syntactic and algorithmic aspects. In many intriguing cases, however, methods from one field have been essential to obtaining proofs in the other. In particular, proof-theoretic techniques have been used to establish important results for classes of algebras in the framework of residuated lattices. This includes both algebras for a wide range of non-classical logics investigated across mathematics, computer science, philosophy, and linguistics, and also important examples from algebra such as lattice-ordered groups. In recent years, researchers from many countries have begun to explore connections between these two fields more closely, providing algebraic interpretations of proof-theoretic methods, and vice versa. The time is now ripe to clarify and exploit these connections.The concrete objectives of the project are: (A) to define uniform proof systems for classes of algebras and logic (such as e.g., lattice-ordered groups or cancellative residuated lattices) not covered by known frameworks, (B) to use proof systems to establish new decidability and complexity results, (C) to investigate relationships between the algebraic property of amalgamation and the logical property of interpolation and use proof systems to settle open problems, (D) to use proof systems to establish correspondences between algebraic properties and admissible rules. The main challenge and originality of the project will be to combine new insights and techniques from algebra and proof theory to tackle these goals.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'An API for Emotional Intelligence'.

assistant: **Concept**

Humans are social creatures. We think and communicate emotionally. However, artificial intelligence (AI) didn't get the memo. We're changing that. Limbic aims to be the cloud computing service for emotional intelligence. We're building an API platform that senses emotional state using signals from the user: facial expression, voice, text, and importantly, physiological signals from wearables. Our software development kit (SDK) is one line of code that sits inside client apps. The code detects which data sources are available (e.g. camera, microphone, text corpus, and wearable heart sensor) and our proprietary machine learning algorithms analyse these to return predictions on the user’s emotional state. Content recommendations for your current mood, personalised app notifications, mental health monitoring - Limbic is an enabling technology with applications across a range of sectors. The first version of our product is a cloud-hosted stress detection service. It is live and already being used by multiple iOS apps, continuously collecting heart data via the Apple Watch. Through this, we have amassed a proprietary database of people from around Europe (the largest of its kind and growing rapidly). In this Horizon 2020 project, we conduct a Feasibility Study that will provide the research and preparation required to launch Limbic in multiple new European and global markets. The proposed project will not only enhance Limbic’s growth, but also unlock the potential of countless more companies, including many SMEs.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The first universal and price-neutral insulin pen' (GO-Pen), addressing dissemination and exploitation.

assistant: **Impact**

The challenge for many people with diabetes (PwD) is that they dont get the right dose of insulin at the right time. This can potentially give long term health issues, and even shorten their lifetime. Today, this is an everyday challenge for more than 13 million people that still inject insulin with a 100 years old outdated technology (syringes and needles) and cannot afford branded insulin and modern pens. GO-Pen ApS developed the 1st affordable, safe, and sustainable insulin injection system that fits the unmet health needs in the worlds most resource constrained population. The UNIPEN system innovation relies on the possibility of refilling a disposable cartridge with any kind of insulin available, resulting in a cost-competitive device to syringes solution improving the accuracy. Now, with the support of the EIC-A funding, we intend to refine the design of the UNIPEN device, demonstrate its design and clinical usability, and fine-tune the scale-up production.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Manufacturing and Modelling of Nano-Scale Molecular Electronic Devices'.

assistant: **Concept**

We will establish a European collaboration to develop manufacturing techniques and theoretical models for nano-scale molecular electronic devices. The objective is to produce molecular electronics with critical dimension less than 10 nm, which can operate at room temperature. A family of functional conducting molecules with reactive end groups will be synthesised, characterised and modelled, and used for making self-assembled three terminal devices in a parallel process. The process will be a combination of chemical synthesis for definition of the critical parts of the devices and conventional lithographic techniques to define leads and connections to other electronic circuits. A demonstration of such a device will put Europe on the leading edge of reset for future electronic manufacturing. Models for new integrated devices for information processing will be developed, that fully takes advantage of the size of molecular electronics. We will establish a European collaboration to develop manufacturing techniques and theoretical models for nano-scale molecular electronic devices. The objective is to produce molecular electronics with critical dimension less than 10 nm, which can operate at room temperature. A family of functional conducting molecules with reactive end groups will be synthesised, characterised and modelled, and used for making self-assembled three terminal devices in a parallel process. The process will be a combination of chemical synthesis for definition of the critical parts of the devices and conventional lithographic techniques to define leads and connections to other electronic circuits. A demonstration of such a device will put Europe on the leading edge of reset for future electronic manufacturing. Models for new integrated devices for information p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'DANTE: Digital Alarm Network and Tracking Equipment for forest fire detection' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Wildfires are a global phenomenon which can have a devastating impact on a country’s population, economy and environment. Although fire suppression costs are increasing every year, there is still a constant increment in the frequency and severity of wildfires. According to EM-DAT, 5.8 million people are affected worldwide every year by wildfires, with estimated economic costs of 45,000 million Euros. DANTE is the integrated low-cost solution for the early detection of wildfires that has received the awards Copernicus Masters 2017 and ESNC 2017. These are international competitions established on the initiative of ESA, GSA and the Copernicus Programme in which DANTE was rated as a business innovation to address EU challenges and an investment opportunity. DANTE is a prompt alarm system which features advanced methods to report and manage a fire within seconds of its starting. It provides the exact geo-referred coordinates of the fire source, tracks accurately the fire as it evolves and guides the firefighting extinguishing operations as a real-time navigator. The system is compatible with existing emergency control rooms and is managed remotely from either the control room or a smartphone with internet connectivity. DANTE has the potential to halve the yearly budget of public and private entities dedicated to wildfires extinction and detection (estimated to be of 10,600 million Euros extrapolating EM-DAT database).DANTE will be commercialised directly by AD TELECOM, including a network of official distributors to maximise the sales worldwide. This project will enhance the ambition of the company to grow and internationalise, targeting an inter-sectorial market in a B2B and B2B2B business model. First sales are expected in 2019, and the annual turnover is calculated to st
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Space qualified GAN Components for Next generation systems'.

assistant: **Innovation**

The main objective of SGAN-Next is to develop a fully European GaN on SiC foundry process and demonstrate outstanding performance at high frequency beyond Q-band, through the design of efficient and robust SSPA, LNA and switch devices for flexible LEO/GEO payloads. For this purpose, the project led by SENER as satellite equipment manufacturer, includes an epitaxy manufacturer (SweGaN), an industrial foundry (UMS), a research foundry (FBH) and two Universities (UNIBO and UAB). Moreover, the consortium count on the two main European satellite prime contractors (ADS and TAS) for the conceptual definition of services and the required system to answer market demand.SGaN-Next aims to secure a European supply chain with GaN epitaxial wafers provided by SweGaN. For this new process, Q/V band power cells will be designed making use of novel processing modules and epitaxial concepts which reduce parasitic losses and increase thermal drain to heat sink. In parallel, UMS provides access to its 0.1-µm GaN technology (GH10-10), which will be optimized and submitted to a space qualification assessment through two runs available for MMICs design and validation. Microwave characterisation of GaN technology performance by model refinement and device characterisation will be addressed to improve MMIC design process along the project.As highly efficient PAs are essential for Telecom active antennas with high number of active units, at least three PAs design concepts are proposed to answer the needs identified at equipment level. The efficiency has a critical impact on the extra power demanded to the system and the increased complexity to dissipate. On the reception side, a design of a LNA as well as a switch for robust RF front-end will be addressed. Last, but not least, packaging techniqu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Genomic and single-cell approaches to establish the molecular basis of stony coral resilience to climate change-related stressors.' (CoralCellSeq), addressing dissemination and exploitation.

assistant: **Impact**

Scleractinian corals are the main builders of the marine reefs that provide a home to roughly a quarter of all marine species. In addition, their photosynthetic symbionts contribute to Earths oxygen, absorb CO2 from the atmosphere, and provide the coral host with most of its metabolic needs. Global changes drastically affecting ocean acidification and temperatures cause the breakdown of this symbiosis. This process is also known as coral bleaching, and it results in a mass decline in coral reefs. Despite the continuous efforts to study this phenomenon, our understanding of the bleaching process is so far limited. It is important to emphasize that different coral species, display distinct responses to stressors, with varying mortality rates following bleaching. Hence, in this action, I will utilize these differences in coral resilience (i) to characterize the cellular and molecular responses to stressors of three corals with different levels of bleaching resilience (Stylophora pistillata, Acropora millepora, and Oculina patagonica); (ii) to identify specific genes that might be key players in coral resilience, and (iii) to design and test pharmacological interventions to modulate coral resilience to thermal and acidification stress. To do so, I will expose corals to thermal and acidification stressors and use single-cell genomics approaches to measure and compare cell type-specific gene expression responses to stressors within and between species. These analyses will highlight candidate molecular pathways and cellular processes responsible for the high resilience of some of these species. Together, this project will provide a high-resolution molecular map of stony coral responses to climate change-related stressors, and it will help me, and others advance towards targete