RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'REAL-TIME OPTIMISATION SOLUTIONS FOR EMBEDDED NONLINEAR MODEL PREDICTIVE CONTROL APPLICATIONS USING THE LPV FRAMEWORK' under Horizon Europe.

assistant: **Concept**

Most modern technological applications of social relevance, such as renewable smart-grids and autonomous cars, consist of systems with complex dynamics operating under fast sampling. These processes exhibit behaviours that can only be accurately represented by means of nonlinear models (thus, complex) with sampling periods of  micro to milliseconds, which means that decision-making should be done under such time. These systems only operate satisfactorily when adequate control methodologies are used, taking into account performance goals, operational constraints and physical metrics. Thus, this project focuses on the development of real-time optimisation for control, using the Model Predictive Control (MPC) framework.MPC is a very established approach, centred on generating decision actions by solving an optimisation problem. Over the last decades, considerable scientific effort has been devoted to the study of MPC, expounding its vast pertinence. Yet, applying MPC with nonlinear models issues increased digital complexity, typically incompatible with real-time environments. The standard practice consists in applying approximated solvers, which are not reproducible nor optimal.Recent works have shown an alternative to render real-time capable algorithms: designing nonlinear MPC using the Linear Parameter Varying (LPV) toolkit. Even though the theoretical side of LPV MPC is presumably established, and several results indicate competitiveness against state-of-the-art solvers, the translation to a practically-viable tool is not yet rendered universal. That is, a ready-for-application MPC solver, using LPV representations, is not yet available. Accordingly, the main goal of this project is to develop a comprehensive real-time optimisation solver, based on LPV MPC. Such a tool
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Joint Initiative for hydrogen Vehicles across Europe 2' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

The spotlight on health impacts of poor air quality and the renewed focus on reducing GHG emissions in recent years provide a strong impetus for cities to seek clean, low carbon transport solutions. When it comes to meeting growing demands for public transport and addressing environmental issues, hydrogen fuel cell (FC) buses offer significant potential. A commercialisation process for FC buses is underway, through which a shared vision has been agreed between vehicle suppliers and their customers. This is based on reducing costs through scale via a phased approach of pre-commercial demonstrations that will provide the evidence for wider uptake of these vehicles in the 2020s.The first step in upscaling FC bus deployment is underway through the JIVE project, which began in January 2017. JIVE 2 is its successor and is Europe’s most ambitious FC bus project to date: 156 buses in 11 cities across six countries. JIVE 2 involves regions with experience of the technology scaling up fuel cell bus fleets (e.g. Cologne), and those seeking to build their knowledge and experience by demonstrating FC buses in small fleets for the first time (e.g. Auxerre). All deployment locations in JIVE 2 share an ambition to increase the size of their FC bus fleets following successful initial demonstrations, hence the participating cities/regions will be natural locations for larger scale roll-out of the technology in the 2020s.A comprehensive data monitoring and assessment exercise will capture the relevant evidence to inform next steps for the sector, and the project’s impacts will be maximised by a high-impact dissemination campaign. This will involve reaching wide audiences via various channels, including a series of international Zero Emission Bus Conferences.The JIVE and JIVE 2 projects to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Novelties, Biases, and Landscapes in Evolution' (NOBLE), addressing dissemination and exploitation.

assistant: **Impact**

Several challenges undermine our ability to predict the course of evolution: the likelihood of evolutionary novelties, the impact of the adaptive landscape, and the influence of developmental biases. NOBLE (NOvelties, Biases, and Landscapes in Evolution) will make use of cutting-edge machine learning, fossil times series, and biomechanical modelling to generate a synthesis of the predictability of phenotypic evolution.  First, NOBLE will use ancestral state reconstruction to determine if origination of and loss of novelties are predictable over macroevolutionary timescales (>113 million years).  Trait origination may be predictable from ancestral morphology, while degree of trait specialization may predict loss. Next,NOBLE will investigate whether convergent evolution is a product of adaptation (as is so often assumed) or chance (rendering it less predictable).  This phase will quantify the magnitude and frequency of morphological convergence between functionally and structurally homologous traits in different lineages. Then, observed convergence will be compared to converge achieved in simulations of Brownian motion (and biased random walks over biomechanically-derived adaptive landscapes.Finally, NOBLE will determine the impact of integration between traits on 1) the strength of within-trait developmental biases and 2) morphological diversity. This is possible because NOBLE’s model organism, cheilostome bryozoans, have a rich fossil record and a colonial growth form – allowing within-genotype, within-population phenotypic variation to be quantified. The influence of trait integration will be examined at five levels of comparison (from within a single species to across multiple clades).Not only will NOBLE begin untangling the Gordian Knot of evolutionary predictability
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'INTEgrating GaN nanowire heterostructures on 2D heteRogeneous plAtforms for photodetectION' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

III-nitride semiconductors (GaN/AlGaN) are strategic materials for photodetection in a broad spectral range from deep ultraviolet to far infrared. These domains can be addressed thanks to interband and intersubband transitions respectively, which cover wavelengths inaccessible to standard III-V semiconductors. Heterogeneous integration of III-N nanowires (NWs) on 2D materials at the same time opens new technological opportunities for advanced optoelectronics and presents fundamental interest to elucidate the physics of van der Waals epitaxy (vdWE). Available research on epitaxial growth of GaN NWs on 2D graphene has demonstrated its promise; however, the scope for improvement remains limited. A number of questions with fundamental significance e.g. the influence of the 2D material in NW growth, controlling factors for NW size/size-distribution, and generalized understanding of vdWE with experimental authentication remain open. INTEGRASION proposes to address these open questions and to achieve a general understanding of vdWE of nitrides on 2D materials for advanced optoelectronic devices. To reach this goal, GaN/AlGaN NWs will be grown on 2D transition metal dichalcogenides (WS2) and comparative analysis will be performed with growth on graphene. The fundamentals of growth process will be assessed experimentally and theoretically emphasizing the impact of 2D materials on the NW growth which is pivotal for heterojunction formation. GaN/AlGaN heterojunctions in multi-quantum well structure will be grown on 2D platforms to demonstrate interband UV photodetection as well as intersubband photodetection in mid- and far-infrared domains. Besides, heterogeneous integration of GaN NWs on 2D platforms will facilitate the post-growth transfer of III-N NWs to flexible substrates wh
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'FLUOR21 : Synthesis, structure and function of fluorinated systems""', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Organofluorine chemistry has played a significant role in the majority of the spectacular scientific and technological developments of thepast century although this is not widely recognised even by the scientific community. Fluoroorganic molecules are key components in anever increasing number of high-value commercially important products particularly in the life science industries. The use of fluorinatedsystems in drug discovery programmes has continued to grow and, at present, approximately 30% of new pharmaceutical andagrochemical systems that enter the market bear fluorine atoms or fluorinated substituents, contributing enormously to the economic wellbeingof the EU as a whole and the health of its citizens. All useful fluoroorganic systems are ‘man-made’ and the key step in developingnew products and applications involving fluorinated derivatives is the synthesis of carbon-fluorine bonds. We will develop new selectivefluorination processes by using both innovative chemoselective methodology and the emerging field of synthetic biology to provide newtechnology platforms beyond the current state-of-the-art. The desire to introduce a fluorine atom into an organic system is often driven bythe fact that the C-F bond imparts unique and highly tuneable control of both geometric and stereoelectronic phenomena within a molecularstructure. The Network’s expertise in handling and analysing fluorinated molecules will allow us to engineer the properties of organic andbiological molecules through the strategic introduction of C-F bonds by molecular editing. A large number of world-leading researchscientists in academia in the various fields of organofluorine chemistry have retired in the recent past and, consequently, if training of ESRsand support of youthful research groups is n
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Security and Safety Modelling' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The SESAMO project addresses the root causes of problems arising with convergence of safety and security in embedded systems at architectural level, where subtle and poorly understood interactions between functional safety and security mechanisms impede system definition, development, certification, and accreditation procedures and standards. Intense market innovation is being held back by this root cause: the absence of a rigorous theoretical and practical understanding of safety and security feature interaction.The proposed solution is to develop a component-oriented design methodology based upon model-driven technology, jointly addressing safety and security aspects and their interrelation for networked embedded systems in multiple domains (e.g., avionics, transportation, industry control).Key elements of the SESAMO approach are:• a methodology to reduce interdependencies between safety and security mechanisms and to jointly ensure their properties• constructive elements for the implementation of safe and secure systems• procedures for integrated analysis of safety and security• an overall design methodology and tool-chain utilizing the constructive elements and integrated analysis procedures to ensure that safety and security are intrinsic characteristics of the system.The relevance of the SESAMO results is guaranteed by the involvement of large partners with significant economic interests in safety and security critical systems in the use case domains: automotive, aerospace, energy, mobile medical, and metropolitan rail transport; a sound group of technology providers (including SMEs); and prestigious research entities (academia and institutes) with deep and complementary multi-domain expertise.SESAMO will enable cost-efficient and systematic design, analysis, deve
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Investigating differentiation using parallel single cell transcriptomic and epigenomic analysis'.

assistant: **Concept**

Past research has identified epigenetic mechanisms including histone modifications as key regulators of transcription and implicated them in cellular differentiation. But while our knowledge about their cell type specific distribution and its influence on transcription has constantly increased, we still know very little about the orchestration of epigenetic and transcriptional changes as they occur during differentiation. To gain a global understanding of the order of events, we aim to identifying changes in gene expression and main transcriptional repressive and promoting histone modifications in cells undergoing differentiation.For this we will develop a novel approach to examine the distribution of histone modifications on a single cell level adapting a method based on antibody targeted micrococcal nuclease (ChIC-seq), which will lead to a modification dependent enzymatic digestion of the DNA. In comparison with existing single cell ChIP approaches this method lacks a precipitation step, leading to minimal material loss per cell, while allowing the use of the variety of histone mark specific monoclonal antibodies. Adapting this approach to the previously described method for co-acquisition of transcriptomic and genomic information from a single cell existing in the lab, will allow the normalization of the histone state using the transcription status of the cell.To analyze the order of changes associated with cell differentiation, we will use single cell RNA seq analysis pipelines (RaceID + StemID) to identify and enrich for cells in between two specific differentiation stages.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Next generation security platform to safeguard critical applications and sensitive digital assets' (ARCAone).

assistant: **Innovation**

The need to improve data protection has only grown in the past years, fuelled by a large number of high-profile cybercrimes that involved taking over digital assets. One of the most significant data breaches has been the successful theft of 143m customer records from a consumer credit reporting agency Equifax (US)—a cybercrime with devastating consequences due to the type of personally identifiable information stolen & its knock-on effect on the credit markets. Impact on the new businesses dealing with novel technology is even more devastating. The largest cryptoexchange Mt. Gox (JP) went bankrupt in 2014 because of an attack that resulted in $473m of cryptocurrencies stolen, greatly damaging public perception of cryptocurrencies & blockchain-related companies.We have developed ARCAone—a combined hardware & software solution that provides a secure execution & storage environment for various digital assets (from tokens & cryptocurrencies to cryptographic keys & other sensitive data).  ARCAone is a highly secure environment that adheres to the existing security standards, supports state-of-the-art security protocols & complies with regulatory requirements. It offers a broad range of functionality & is future-proof.Since our foundation in May 2018 we have raised €1.4m & earned €246,000 in beta sales. Our team members have worked on the most secure software such as OpenBSD & OpenSSH.We will commercialize ARCAone platform through vertical applications built on top of it—we are building the 1st applications ourselves & will involve 3rd party developers for the others. This will allow us to focus on the ARCAone SDK & application marketplace while achieving the scale through 3rd party applications. We will start with the financial segment & IoT, then move to cloud services & ot
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Mathematical Models and High Performance Computing for Deposition and Absorption in Physiological Flows'.

assistant: **Innovation**

The project involves the development of mathematical models and their implementation as software code for high performance computing clusters. The physical problem studied involves two related topics: particle deposition and solute absorption in respiratory airways, and tumour metastasis in arterioles and capillaries. The aim is to couple micro-scale phenomena to large 3D incompressible flow simulations. These topics are chosen for their clinical relevance and complex, coupled nature that requires large-scale computing.The numerical tools to be developed are twofold, namely 1D geometric multi-scale networks and Lagrangian mesh-free schemes. The 1D models will serve as fluid boundary conditions of the main conduit, and represent the vascular bed in the tissue. The 1D models are based on Cosserat director theory. A Lagrangian mesh-free scheme will be used to model the multi-component fluids (whole blood and particle-laden air). This approach will easily cope with multi-body interactions and the deformation of the corpuscles; hence it will model the micro-scales and will interface with existing incompressible solver at the host institution. The Lagrangian mesh-free method is based on radial basis function and point interpolation schemes.The facilities at the host institution are among the best in Europe for high performance scientific computing. The supervisor is experienced in computational mechanics, parallel programming, and biomedical applications. These include simulations of large 3D incompressible flow simulations in the respiratory airways and extensive branching arteries, which are both the applications in this project.The proposed project integrates the candidate's field of expertise in numerical analysis and fluid mechanics in physiology, with high performance c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Global and Regional Emissions Estimates of Non-CO2 Greenhouse gases and Ozone Depleting Substances'.

assistant: **Concept**

The Montreal Protocol is widely regarded as the most successful international environmental treaty of all time, with substantial benefits to the stratospheric ozone layer and climate. However, recent work has shown that continued vigilance is needed following the first major violation of the Montreal Protocol, originating, at least in part, from eastern China. Since publication, Chinese authorities have reported major enforcement activities to address the problem. However, the work highlighted several remaining scientific challenges that must be addressed to continue to support the Montreal Protocol and, for climate, the Paris Agreement. Firstly, the magnitude of change in global emissions could not be reconciled with that inferred from eastern Asia, suggesting that the models could not accurately simulate year-to-year atmospheric trends, that the uncertainty estimates are insufficient, that as-yet-unidentified emissions occurred elsewhere in the world, or some combination of each. Secondly, the work highlighted the critical need to develop robust global and regional emissions inference capability for the more than 40 greenhouse gases and ozone depleting substances regulated under the Montreal Protocol and other agreements. This project will work collaboratively between the two major global monitoring networks of non-CO2 greenhouse gases and ozone depleting substances – NOAA in the USA and the international AGAGE consortium – to develop new models and statistical methodology to better quantify emissions of non-CO2 greenhouse gases and ozone depleting substances using atmospheric measurements and models of atmospheric transport, and to improve the accuracy of national and international emissions reporting.


**Keywords:** ozone depletion, greenhouse gas emissions, invers