RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Hydrogen storage in hydrides for safe energy systems (HYSTORY)' under Fifth Framework.

assistant: **Concept**

A major unresolved problem for the introduction of the 'Hydrogen Economy' and the extensive use of hydrogen as energy carrier is efficient and safe storage of hydrogen. High pressure compressed gas storage is energy intensive if high volume efficiency is desired, and liquid and solid hydrogen storage even more so. Storing hydrogen in the fun of solid metal hydrides from which it can readily be recovered by heating is an alternative and safe, highly volume efficient storage method. For typical applications, however, both volume and weight efficiencies are important. Conventional metal hydrides (MH) suffer from low weight efficiencies and the challenge is to improve them substantially. In addition, the temperature and pressure of operation of the materials need to conform to specifications set by the practical applications. With a view to responding to these challenges, HYSTORY aspires to advance significantly the state-of-the-art in three MH classes and develop hydrides based on lightweight, low cost elements with improved hydrogen storage properties. The proposal is driven mainly by the material developers and industrial producers while including a number of end-users that will integrate and test the respective hydrogen storage systems (material & tank) in stationary (power generation) and marine (FC-based boats) fuel cell applications.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Rational molecular Assessments and Innovative Drug Selection'.

assistant: **Objectives**

Cervical cancer (CC) is the second most common cause of cancer deaths in women worldwide. The main objective of the RAIDs project is to use this model system which is accessible to repeat biopsies to learn how to stratify patients into targeted therapies.  The patients’ tumors will be classified into molecular subtypes based on their molecular profile by use of high-throughput technologies (sequencing, RPPA) combined with integrative bioinformatics analysis. Stratification is a learning process which will need constant readaptation. It will rely on prognostic and predictive biomolecular information gained from patients who will receive either standard therapy (the cognitive cohort) or patients who receive (first generation) targeted therapy. Bioinformatics will be an essential tool to allow integrative genome/proteome analysis and provide functional interpretation of the results at each step. Machine learning techniques will be used to select the most reliable biomarkers. These tools will be used to predict response to cc treatment or progression. Moreover, systems biology approaches will be used to unravel the gene regulatory networks and signaling pathways involved in the tumor progression and should be helpful to select predictive biomarkers and putative drug targets.Tumor material will be sampled before and following standard therapy or therapeutic HPV vaccination and/or novel targeted drug treatments. Clinical annotation by imaging methods as well as through biomarkers will have quality control procedures and relevant statistical models will be applied.RAIDS is a multidisciplinary approach integrating genomic studies, protein arrays, viral genotyping and immunohistochemical investigations on CC cells and tissues between academic clinical centers and SME’s .The proj
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'AN AUTOMATIC PENDULATION CONTROL SYSTEM FOR OFFSHORE LIFTING OPERATIONS'.

assistant: **Innovation**

The general aim of this project is to demonstrate, within a two-year time frame and through the realisation of a working prototype, an automatic control system that reduces pendulation of suspended loads in offshore lifting operations. More specifically the goals of Active Pendulation Control System (APCS) projects are :* to demonstrate the technology involved in controlling pendulation with a scaled up plant tested and evaluated under real operating conditions.* to assess and evaluate the capability of the system in improving the effectiveness and overall safety of offshore lifting operations.The goal of this project is to demonstrate, within a two-year frame, an automatic system for pendulation control of the suspended load in offshore lifting operations. Launch and recovery of an object from a vessel at sea has always been a hazardous operation and realisation of this project will provide a technological solution to the problem. It is our objective that, after the two year period and following a successful demonstration, the technologies involved and the complete prototype package will be available for commercialisation. Application of the APCS in handling equipment used by the offshore support and construction vessels will provide a cost effective and safer rough weather load handling capability that will be of considerable benefit to operations associated with deeper waters and the development of marginal fields.The vast majority of crane systems used offshore have no means to compensate for the motions induced on the suspended load caused by the sea, wind and other external disturbances. These induced motions take the form of heave (linear displacement) and pendulation (angular displacement) of the load. Previous efforts on the compensation of disturbances induced
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'High frequency stimulation of the subthalamic nucleus: a therapeutic approach to parkinson' s disease' (1998-2002), addressing dissemination and exploitation.

assistant: **Impact**

Parkinson's disease (PD) is a neurodegenerative illness with high prevalence and long course characterized by severe motor and cognitive impairments. Clinical trials have recently shown that chronic high frequency stimulation (HFS) of sub thalamic nucleus (STN) alleviates Parkinson Ian motor symptoms and elodea-induced complications at advanced stages of PD. However, little is known about the functional mechanisms of this new therapeutically tool, its long-term motor effects and consequences on cognitive functions. The aim of this project is thus to address these issues. Behavioural consequences of STN HFS will be specified in terms of motor and cognitive functions in PD patients and in animal models. Biochemical and cellular events underlying the behavioural effects of STN HFS and neuropath logical factors that may govern its efficacy will be investigated in animal models. The results are expected to have major socio-economic impacts by improving indication of STN HFS in the course of PD.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'EU-Brazil Open Data and Cloud Computing e-Infrastructure for Biodiversity', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The main goal of EUBrazilOpenBio is to deploy an e-Infrastructure of open access resources (data, tools, services), to make significant strides towards supporting the needs and requirements of the biodiversity scientific community.This data e-Infrastructure will result from the federation and integration of substantial individual existing data, cloud, and grid EU and Brazilian infrastructures and resources across the biodiversity & taxonomy domain namely Catalogue of Life, OpenModeller, D4Science-II and Venus-C. The breadth & depth of the resulting data infrastructure & the openness of its resources will enable a large variety of new cost-effective, cross-disciplinary virtual research environment applications thus opening the way to its widespread adoption and exploitation by the worldwide biodiversity scientific community.Accelerating the creation of a data e-Infrastructure of open access resources pursues interoperability with end-user technologies, & contributes to social, environmental agendas. Europe through international cooperation can facilitate the exploitation of European excellence & results in data infrastructure & cloud computing to enhance European competitiveness & job opportunities. Project goals are two Use Cases: 1. Integration between Regional & Global Taxonomies; 2. Data usability & use of ecological niche modelling. The interoperation runs through all infrastructures: hardware & computing facilities, portals & platforms, scientific data knowledge infrastructuresPrincipal Outputs: 2 user scenarios, a software platform with a specific Software Development Cooperation Environment, computational e-Infrastructure, at least 50 seed resources (dataset, services, platforms, computational & storage resources) offered to the biodiversity community, a consolid
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Identification of genes controlling the innate immune response in mosquitoes infected with the malaria parasite, Plasmodium' to be submitted under Sixth Framework.

assistant: **Abstract**

This project aims at the identification of the genes controlling the innate immune response in mosquitoes infected with the malaria parasite, Plasmodium. There is ample evidence that mosquitoes and the malaria parasite have co-evolved and that the immune system of the mosquito greatly affects the ability of the parasite to undergo rather complex development in the insect. A large number of genes are involved in insect immunity, most of which have been identified in Anopheles gambiae. In order to debilitate the insect's immune response system (and thus lower its fitness), ideally one would want to identify genes specific to a particular mosquito species and particular parasite species. The fact that the deadliest form of human malaria, that caused by P. falciparum, is transmitted by only five species of Anopheles in continental Africa and these represent four independent evolutionarily events, is of outmost importance for the current project. The four natural replicates will be used to determine the common pat terns specifically associated with the specific species of malaria parasite. In particular, the patterns of amino acid substitutions in genes involved in the insect's immune system will be analyzed. Adequate evidence exists in support of the view that prot eins involved in host-parasite interactions undergo rapid evolution when the association arises. This association has arisen four independent times, thus making the evolutionary approach to identify crucial proteins particularly promising. Hundreds or thou sands of years of evolution will be exploited in order to reveal specific interactions that have arisen under natural conditions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Text and Idea of Aristotle's Science of Living Things' under Horizon Europe.

assistant: **Concept**

Text and Idea of Aristotle’s Science of Living Things (TIDA) pursues two objectives, one philosophical, the other philological, both of which can only be achieved in tandem: subjecting Aristotle’s treatise on the soul, the De Anima (DA), and related treatises, to a new and comprehensive philosophical interpretation, while making available the original Greek texts in a way that complies with the standards of contemporary textual criticism. Philosophically, the aim is to replace the interpretive approach that governed philosophical discussions around the DA for the past 5 decades with a more coherent and philosophically more informative interpretation. According to the received approach, the argument of the DA falls into the domain of ‘philosophy of mind’. This assumption, fruitful though it was for our understanding of many of the DA's arguments, obfuscates the main aim and purpose of the treatise. TIDA shows how the DA is not concerned with the philosophy of mind as such, but with defining the first principle of the science of living things; we show how the DA divides explanatory labour with the other treatises pertaining to that science, and – most importantly – what the resulting scientific theory of living things has to say about the issues of the philosophy of mind. Philologically, the goal is to produce reliable critical editions of the relevant texts, print and digital, which we – astounding as it might seem – still do not possess. As the constitution of the texts will depend on the philosophical evaluation of alternative manuscript readings, only the closest collaboration between textual critics and philosophers will yield progress. There is reason to expect improved original texts and a genuinely new and more informative perspective on Aristotle on the mind. In
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Consumer-driven re-engineering of the distribution network in the apparel industry', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Apparel Industry in Europe employed about 2 million people in 1993 in the design and manufacturing of apparels (i.e. garments, clothing and clothing accessories). Starting from the late '80s, and particularly in the last few years, major changes in the market (which is shrinking), in the social context (consumers' purchase attitudes, behaviors, tastes etc. tend to change very quickly following the fast changes in the models proposed by mass-media) and in the economic scenario are forcing the Apparel Industry to critically revise its main beliefs and competitive strategies. Traditional approaches to reduce product costs (and, thus, increase profits) through reduction of production costs are today no longer as effective as in the past. The question is: where else to intervene to reduce product costs and to improve responsiveness to customers ? A survey recently conducted by Kurt Salmon Associates, a major management consulting firm, has revealed that inefficiencies in the distribution network in the Apparel Industry may accounts for up to 55% of the total products costs, from the end-consumer viewpoint, while at the same time severely hampering the responsiveness of the total system. The fragmentation of the logistic chain into a very large number of actors (Points of Sales, Sales Agents, Distributors), as well as the experience from other Industrial Sectors, such as Food and Grocery, which shows a similar market structure, suggests that an higher degree of integration along this chain may lead to enormous benefits for all the involved actors. The CODE Pilot Project intends to transform the way in which the Apparel Industry manage the distribution network, moving from a sell-in driven strategy to a sell-out driven one.In a sell-in driven scenario, apparel suppliers focus
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Semantic-based Interoperability Infrastructure for Integrating Web Service Platforms to Peer-to-Peer Networks' to be submitted under Sixth Framework.

assistant: **Abstract**

The objective of the project is to develop a secure semantic-based interoperability framework for exploiting Web service platforms in conjunction with Peer-to-Peer networks.Web services have become a main thrust of the IT industry with its universally accepted standards like SOAP (Simple Object Access Protocol) for invoking services and WSDL (Web Services Description Language) for describing the technical specifications of the services. There are well established service registries like Universal Description, Discovery, Integration (UDDI) and electronic business XML (ebXML). From the point of Web services, there seems to great opportunities in interoperating with P2P networks. Although service registries facilitate service discovery, they are centralized and joining a service registry requires special administrative arrangements in contrast to Peer-to-Peer (P2P) networks. The barriers to starting and growing P2P systems are low. Therefore especially for SMEs it is advantageous to make their services available through a P2P network. Yet the full power of Web services can be exploited only when any service whether on a service registry or advertised through a peer becomes available to the community. There is a major problem to be solved to realize this vision: the semantic interoperability problem. Web services have a lot of properties like their counters parts in real life that has to be used in the search. In this project we will realize a semantic based infrastructure which will allow the Web services on well-established service registries like UDDI or ebXML to seamlessly interoperate with Web services on P2P Networks. The infrastructure will be used to develop an innovative business pilot application in tourism industry. The travel ontologies to be developed and the s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Development of targeted DNA-Chips for High Throughput Diagnosis of NeuroMuscular Disorders' under Seventh Framework.

assistant: **Concept**

Inherited Neuromuscular Diseases (NMD) form a large group of diseases including Limb-Girdle Muscular Dystrophies (LGMD), Congenital Muscular Dystrophies (CMD), Duchenne and Becker Muscular Dystrophies (DMD/BMD), or Charcot-Marie-Tooth disease (CMT). Within a given disease group genetic and clinical heterogeneity is the hallmark. The precise diagnostic of neuromuscular diseases thus requires extensive clinical examination and targeted complementary tests. Additionally, since many of the disease causing mutations are known, molecular and genetic tests are performed to confirm and precise the diagnostic. According to presently available technologies, this is highly complex and time consuming. Thus, many patients remain devoid of genetic confirmation of their disease. More importantly, new cutting edge therapies cannot and will not be possibly envisaged in absence of a precise genetic diagnosis. New molecular diagnosis tools, enabling quick, reliable and cost-effective sequencing of numerous NMD genes are thus required. The development of such tools would allow performing the genetic diagnostic of NMDs patients. DNA chips have the potential to address this issue, in a time and cost effective way. The goal of this project is to i) design and validate a DNA Chip for sequencing genes responsible for LGMDs, CMDs, DMD/BMD, and CMTs, and ii) use the DNA Chip technology to identify new genes/mutations involved in these inherited NMD and increase the molecular diagnosis/patients ratio. This approach will be based on a gene candidate approach. NMD-Chip will thus lead to the development of a novel sensitive and reliable (98%) diagnostic tool, with time and cost effectiveness dedicated to neuromuscular disorders. In total, NMD-Chip, based on human genome knowledge and an advanced read