RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Yearly Colloquium of European Group for Organizational Studies, theme of the year 2000 is 'Organizational Praxis'' in the context of a Fifth Framework call.

assistant: **Objectives**

The EGOS (European Group for Organization Studies) organizes an annual conference, which is distinguished by its international participation and scholarly contribution to the forefront of organization theory. Besides the colloquium's changing thematic groups, the EGOS Colloquium also allows for the establishment of international work groups to pursue research into issues of Particular interest to the European Community.The changing global and European economic contexts create challenges to business and public sector organizations and makes transformation of managerial and organizational practices to core issues. In relation to these organization theory has a considerable scientific and practical potential, which in order to be realized requires a strengthening of the European community of organization researchers -and in particular the investment in developing a new generation of researchers.EGOS has decided to give priority to supporting the new generation of organization researchers and thus applies for EU funding for the participation of 20 phd-students in the year 2000 Colloquium in Helsinki with Organisational Praxis" as theme. The doctorate students will be selected by the convenors, based upon quality of the submitted paper abstracts, and taking into consideration lack of other funding possibilities and distribution between European countries.The working group structure of the colloquium provides allows close social interaction for young scholars to meet with experienced researchers, get comments for their papers in the group sessions and during the social time allocated in the programme. This is a step towards organising of doctoral tutorials in the forthcoming colloquia and also other types of pre- and post-conferences activities.ftp://ftp.cordis.lu/pub/improvi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Investigation of the plant miRNA pathway' (PLANMIP), addressing dissemination and exploitation.

assistant: **Impact**

MicroRNAs (miRNAs) are 20-22 nt non-coding RNAs that regulate gene expression post transcriptionally via base pairing to complementary target mRNAs. They have fundamental importance for development and stress adaptation in plants and animals. Although a molecular frame work for miRNA biogenesis, degradation and action has been established, many aspects of this important gene regulatory pathway remain unknown. This project explores four main points. First, we propose to use genetic approaches to identify factors required for translational repression by miRNAs in plants. This mode of action was until recently thought to occur only exceptionally in plants. My post doctoral work showed that it occurs in many miRNA-target interactions. The mechanism remains unknown, however, leaving open a fertile area of investigation. Second, we wish to test specific hypotheses regarding the in vivo role of miRNA mediated endonucleolysis of mRNA targets. Long believed to serve exclusively as a degradation mechanism, we propose to test whether this process could have important functions in biogenesis of long non-coding RNA derived from mRNAs. Third, my postdoctoral work has provided unique material to use molecular genetics to explore pathways responsible for miRNA degradation, an aspect of miRNA biology that only now is emerging as being of major importance. Finally, our unpublished results show that plant miRNAs and their associated effector protein Argonaute (AGO) are associated with membranes and that membrane association is crucial for function. This is in line with similar data recently obtained from different animal systems. We propose to use genetic, biochemical and cell biological approaches to clarify to which membrane compartment AGO and miRNAs are associated, how they are recrui
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Intelligent plug-and-play digital tool for real-time surveillance of COVID-19 patients and smart decision-making in Intensive Care Units' (ENVISION).

assistant: **Concept**

Within only six months, over 7.4 million people have been diagnosed with SARS-CoV-2. In the most severely hit countries, more than 10% of infected patients have received treatment in Intensive Care Units (ICUs). Insufficient data and limited knowledge on the disease as well as the lack of tools to support the intensivist in making accurate, timely and informed decisions has led to high mortality rates. Continuous surveillance, the collection and intelligent analysis of data from many sources, including ventilators and electrical impedance tomography, would allow intensivists to decide on the best suitable treatment to accelerate the recovery of the often comorbid COVID-19 patients, while reducing the burden on clinical staff and healthcare costs. This information would also increase our understanding of the yet unknown course of disease, supporting other stakeholders in the quest for new therapies.In ENVISION, our multidsciplinary public-private consortium will advance an innovative digital tool, Sandman.MD, a real-time and plug-and-play monitoring app, to an intelligent decision-support system for monitoring, prediction and treatment of COVID-19 patients in ICUs – the Sandman.ICU – reaching Technology Readiness Level 9 and ready for CE marking by the end of the project. The app has been developed by our SME partner app@work and successfully introduced by several hospitals in Germany for use during the perioperative period. Sandman.ICU will be integrated into an AI-driven data analytics suite with predictive modelling tools and enhanced with a smart alert functionality. The digital tool will be validated and demonstrated in 14 hospitals across Europe. Our Health Technology Assessment expert partner will demonstrate the economic and societal value of Sandman.ICU, while a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Smart Mobile awarenes and safety system for workzone invasion', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Current technologies applied to road maintenance safety management do not provide adequate warning due to technological limitations that reduce safety system reliability, such as: inaccurate alarms, reduced signal transmission distance, high investment (~2.000€/sensor), or do not meet portability & flexibility needs. This causes that 75% of all road maintenance worker deaths are caused by runovers. To overcome those limitations, Secmotic, Spanish SME, expert in innovative IoT (Internet of Things) solutions for the digital transformations of cities and industry and, has developed ZIMASS, a smart, portable and reliable awareness & safety system for work zone invasion. ZIMASS is based on computer vision and artificial intelligence, to create a virtual security zone, recognize risky situations, and alert workers by connected wearable devices. ZIMASS offers a competitive new solution (3.750 €/system – 10 detection nodes + 5 wearables-) with low exploitation costs (€0,015/ day), and payback period ≤ 2 months. ZIMASS, unmatchable reliability (response time < 1s), increases work safety and work quality, as it reduces sick leaves with its associated financial saving, therefore increasing work productivity. Our smart plug & play solution is customized & adaptable to every application and support. ZIMASS successful launch will be by 2020, boosting our revenues and gross profits to respectively €12,8 M and €3,4 M, with a profitable ROI of 55% by the 5th year. After 5 years, we will sell 3.420 ZIMASS systems, and we will create 15 new job opportunities. We will count with key technical & commercial partners (as S2E), and key end users support as final validators (see support letter of Ferrovial Servicios, Ferrovial Agroman, Cintra, Calle 30 and Emasesa).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Molecular trade-offs between adaptation to salinity and immunity in three-spined sticklebacks' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Climate change and its consequences on the oceans represent major challenges for marine species, which either need to migrate to remain in their optimal niche or need to adapt to avoid extinction. While the genetics and genomics of adaptation are well studied to predict the future state of marine biodiversity, major gaps remain about the role and mechanisms of phenotypic plasticity within and across generations. Particularly, climate change is multifold and non-parallel stressors limit evolution: indeed, organisms cannot allocate infinite resources into all responses, and trade-offs therefore emerge. Because stressors are often investigated in isolation, our overall understanding of molecular trade-offs is limited. In this project, we will study the impact of two major concomitant challenges induced by climate change, namely the change in ocean salinity and the associated change in the parasite community. We will use the three-spined stickleback (Gasterosteus aculeatus) fish from the Baltic Sea, which has been coined a “time machine” because of its rapid salinity change mimicking the future of the oceans. We will investigate the osmoregulation-immunity trade-offs mediated by DNA methylation. After identifying these trade-offs, we will use a network approach to shed lights on the interactions of methylation within gene clusters, and their expression (RNA-seq). We will use data generated by the hosting group on (1) natural populations of the Baltic Sea and (2) experimental acclimation to salinity, completed by a common garden experiment testing the induction of trade-offs by both parasite infection and salinity change. This project will advance our understanding of the mechanisms of phenotypic plasticity in marine organisms and their consequences on adaptive evolution.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Understanding and Controlling Glycosylation Reactions'.

assistant: **Objectives**

This proposal aims to understand and control glycosylation reactions. In a glycosylation reaction a “donor” glycoside and an “acceptor” (the nucleophile) are united to form an oligosaccharide. Although it is the central reaction in carbohydrate chemistry, our understanding of this reaction, in terms of stereoselectivity and productivity is still limited. The structural variation in the building blocks leads to a complex continuum of SN2-SN1 mechanisms that operates and it is currently impossible to predict where in the continuum the reaction exactly takes place. This proposal provides fundamental insight into the outcome of glycosylations by studying both the activated donor glycoside and the acceptor nucleophile. Activation of a donor glycoside leads to different reactive intermediates, covalent anomeric species (most often triflates) and oxocarbenium ion-like species. The relative reactivity of these species is quantified to generate novel reactivity charts. The covalent species are studied by innovative competition experiments, kinetic studies and NMR spectroscopy. The (fleeting) oxocarbenium ion-like intermediates are probed by a computational approach and by “super-acid NMR” studies in which stable glycosyl cations are generated and studied in super-acid media. The reactivity of glycosyl acceptors is systematically studied in a set of SN2 or SN1-type glycosylations. Using kinetic studies and competition reactions charts of acceptor nucleophilicity are compiled. The reactivity of the donors and acceptors is matched using a family of tailor made “reactivity modulators”, spanning a broad reactivity window bridging the reactivity gap between the building blocks leading to predictable glycosylations. The developed methodology is employed in automated solid phase synthes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Mechanisms of specificity during symbiosis signalling'.

assistant: **Objectives**

The availability of nitrogen and phosphate are the major limitations to plant growth and many species of plants have entered symbiotic interactions with microbial partners that aid in the uptake of these nutrients from the surrounding environment. Legumes form symbiotic interactions with mycorrhizal fungi that aid in the uptake of phosphate and with nitrogen fixing rhizobial bacteria that provide the plant with a source of nitrogen in the form of ammonium. A better understanding of these symbiotic processes will provide opportunities to improve and expand these symbiotic interactions in important crop species, which could greatly enhance agricultural productivity and sustainability. In both of these symbiotic interactions signal exchange between the plant and the symbiont is crucial for the establishment of the interaction. While these two symbioses initiate very different developmental responses in the plant, they share a common symbiosis signalling pathway, that is involved in the recognition of the symbiotic signalling molecules. Despite this conservation in signalling, specificity must be maintained in order to ensure appropriate responses in the plant to the two different symbionts. Calcium acts as a central secondary messenger in the symbiosis signalling pathway and we have evidence suggesting the nature of the calcium signature defines the mechanism of specificity. This proposal will address how the two symbionts are differentially perceived and the mechanisms by which the calcium signal can define specific symbiotic responses, despite this conservation in the signalling pathway.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Launching the World’s Most Power Efficient GNSS System-On-Chip'.

assistant: **Innovation**

An increasing amount of IoT devices need to be tracked. All these applications rely on the Global Navigation Satellite Systems. GNSS is a system that uses satellites to provide autonomous geo-spatial positioning. Today, almost 27 billion connected devices are connected globally within the IoT. By 2025, this will multiply to over 75 billion.Qualinx has invented QLX300, the world’s most power efficient GNSS system-on-chip (SoC). QLX300 utilizes its patented discrete- time/digital RF (DRF) technology. This allows it to deliver the most power efficient GNSS solution while operating from a 1V rechargeable coin-size battery. It has the smallest form factor of less than 4 mm squared, and it offers the lowest BOM cost. It is implemented in Global Foundries’ cutting-edge 22nm FDX process, and it has an off-leakage current of less than 1uA while operating up to 105 degrees Celsius. With this capability, the solution is addressing the need for radio solutions with long battery life, driven by the portable IoT, wearable, and mobile applications in volume production. Qualinx DRF technology suits well for Bluetooth, ZigBee, Thread, GNSS, and other IoT standards demanding an ultra-low-power consumption. The serviceable available market is estimated to be 210 million units.For Europe, the IoT represents the next step towards the digitization of society and the economy, where objects and people are interconnected through communication networks and report about their status and/or the surrounding environment. In fact, the European Commission estimates the market value of the IoT in the EU to exceed €1 trillion in 2020. The IoT merges physical and virtual worlds, creating smart environments. The European Commission actively cooperates with industry, organizations and academic institutions
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'ECONOMIC EVALUATION OF PAVEMENT MAINTENANCE & LIFE CYCLE COST AT PROJECT AND NETWORK LEVEL' in the context of a Fourth Framework call.

assistant: **Objectives**

Main objective of this contract is to develop an integrated road pavement maintenance system. Two groups will look at two different system levels: the PAV-ECO group will focus on a project level, the RIMES group at network level.For the RIMES group, the following more specific objectives can be distinguished:- An integrated network level management model for use by policy makers in order to determine maintenance standards and strategies, appropriate budget levels, and allocation of funds between competing network maintenance needs.- A work programming model for preparing optimal road infrastructure maintenance programmes under constrained budgets, based on the prionciple of maximisation of economic benefits.- Optimum maintenance standards and strategies for different road classes in EU countries, based on the resultss of life cycle cost analyses.- Guidelines for road infrastructure data collection requirements.For the PAV-ECO group, the following specific objectives can be distinguished:- A method to evaluate life-cycle costs of road maintenance.- Several cost performance models, required to apply the above method.Links with other projects, tasks, areas, programmes, policy actions:There is a link with the PARIS project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Partnering for the Future Hungarian EU Presidency Conference' (BibeConf).

assistant: **Innovation**

The Hungarian Presidency of the Council of the EU 2024 (Hungarian EU Presidency) aims to organize a series of discussions on research and innovation priorities in the field of bioeconomy. The series of events will commence on July 4 in Brussels and will culminate in a high-level event on December 4-6, 2024. This proposal aims to support the organization of the Presidency event in December by financing some of the costs not covered by the central budget of the Hungarian EU Presidency coordination. The high-level conference will be organized in collaboration with the European Commission and the Standing Committee on Agricultural Research under the auspices of the BIOEAST Initiative. The event is expected to attract 300-350 participants, including European Commissioners, representatives from national and EU institutions, diplomats from Member States, and policymakers from various ministries, as well as stakeholders from academia and the private sector. Additionally, EU candidate countries from the Western Balkans, Ukraine, Moldova, and Georgia will participate. The science-policy discussions at this event aim to enhance the understanding of priorities at both the Member States and European Institutions levels and will help guide the future strategic research and innovation agenda for the macro-region. The BIOEAST Initiative aims to establish a pan-European research and innovation partnership with a focus on Eastern Europe. During the Hungarian EU Presidency the initiative will center discussions on four thematic areas: healthy soils, freshwater resilience, food systems security, and modern biomanufacturing. These topics will be discussed during the high-level official Presidency event scheduled for December 4-6, 2024, Budapest, Hungary. The financial support is crucial to