RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'HARMONIzation and integrative analysis of regional, national and international Cohorts on primary Sjögren’s Syndrome (pSS) towards improved stratification, treatment and health policy making' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

HarmonicSS vision is to create an International Network and Alliance of partners and cohorts, entrusted with the mission of addressing the unmet needs in primary Sjogren Syndrome; working together to create and maintain a platform with open standards and tools, designed to enable secure storage, governance, analytics, access control and controlled sharing of information at multiple levels along with methods to make results of analyses and outcomes comparable across centers and sustainable through Rheumatology associations. The overall idea of the HarmonicSS project is to bring together the largest well characterized regional, national and international longitudinal cohorts of patients with Primary Sjögren’s Syndrome (pSS) including those participating in clinical trials, and after taking into consideration the ethical, legal, privacy and IPR issues for sharing data from different countries, to semantically interlink and harmonize them into an integrative pSS cohort structure on the cloud. Upon this harmonized cohort, services for big data mining, governance and visual analytics will be integrated, to address the identified clinical and health policy pSS unmet needs. In addition, tools for specific diagnostic procedures (e.g. ultrasonography image segmentation), patient selection for clinical trials and training will be also provided. The users of the HarmonicSS platform are researchers (basic/translational), clinicians, health policy makers and pharma companies. pSS is relevant not only due to its clinical impact but also as one of the few “model” diseases to link autoimmunity, cancer development (lymphoproliferation) and the pathogenetic role of infection. Thus, the study of pSS can facilitate research in many areas of medicine; for this reason, the possibility for sus
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Contextual specification of fibroblast-driven causalities in chronic intestinal inflammation and fibrosis' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Inflammatory bowel disease (IBD) is a severe, chronic pathology presenting with progressive intestinal inflammation and fibrosis, whose exact causes and key pathways remain poorly defined. Stromalimmune cell interactions have recently gained momentum in conceptualizing tissue homeostasis and our lab offered solid evidence establishing fibroblast heterogeneity and dominant roles in intestinal pathophysiology. Our recent preliminary evidence, indicated diverse spatial distribution of subsets of activated fibroblasts and revealed synergistic interplays of important inflammatory pathways driving pathogenicity. Detailed insights into such contextual complexities remain obscure. Here, we propose a novel unifying hypothesis that progressive IBD is orchestrated by specific subsets of fibroblasts, becoming causal to pathogenesis, depending on contextual information dictated by origin, topology, and cross-talks with immune or stromal cell types.We propose to use single-cell spatiotemporal phenotyping to deconvolute fibroblast subset-specific functions in disease-staged, fibrotic and non-fibrotic animal models of IBD. We aim to: (1) Map dynamic chromatin and gene expression programs that define cellular heterogeneity and infer cell interactions to build an IBD connectome atlas (2) Analyse the origin, spatial distribution, plasticity and lineage trajectories of intestinal fibroblasts and reveal potential functions of pathogenic subsets (3) Perform discovery screens and functional validations on known (TNF, IFN, TGFb and interleukins) and novel fibroblast-subset-specific pathways focusing on potential synergistic interplays (4) Employ clinical material to validate involvement of the most prominent new pathways in human.The proposed research should help tackle the complexities of chr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'New Approaches to Counting and Sampling' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Probabilistic models have been adopted in almost all scientific disciplines. Many related computational problems arise, involving estimating the probability of certain events, or drawing samples from a desired distribution. These problems, technically known as counting and sampling problems, are the main focus of the NACS project, with an emphasis on rigorous mathematical analysis.Markov chain Monte Carlo algorithms have been designed and applied for counting and sampling long before the computational complexity theory, and they are among the oldest randomised algorithms. There had been dramatic progress in the rigorous analysis of Markov chains in the golden era of early 90s, which has lead to many landmark results. Nevertheless, after about 30 years' development, the complexity of many fundamental problems remains open. In the last few years, a number of exciting approaches have emerged, resulting from new perspectives and surprising connections. Consequently, a lot of old challenges start to crumble. It is now the right time to revisit some of the oldest problems in counting complexity.The emerging techniques include brand new sampling frameworks, such as partial rejection sampling, as well as new ways to analyse traditional algorithms, especially Markov chain algorithms. They can be classified under two themes: those connected with the Lovasz local lemma and those with the geometry of polynomials. The goal of this project is to unleash the full power of the new approaches, to establish novel algorithmic paradigms, and to attack major open problems, such as sampling perfect matchings in general graphs. Due to the fundamental nature of counting and sampling problems, success of the project will also benefit a number of related areas, ranging from combinatorial optimis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Lowering the environmental impact of fresh fish logistics' (2014-2020).

assistant: **Concept**

Each year around 6.3 million tons of fish are distributed around Europe. Maintaining the cold chain during distribution is critical to avoid spoilage and guarantee freshness, ensuring the highest quality fish is delivered. Expanded polystyrene (EPS) boxes are usually used with this purpose. However, they are a major threat to the environment, since they are manufactured from fossil fuels and are used as single-use disposable packaging, having thus a high carbon footprint. Moreover, due to the low recycling rate of EPS, most of these boxes end up in landfills, contributing to the vast amounts of plastic waste generated. An increasingly stringent regulation on plastic waste (including the possibility of EU policies limiting EPS use), and a growing demand from consumers for sustainable practices are driving fish producers to look for plastic-free eco-friendly packaging alternatives. However, currently available options on the market still fail either on performance or cost.Cool Wool ehf was founded in 2017 with the aim of developing the Cool Wool box: an insulating box for the fishing industry that will lower the environmental impact of its supply chain. Cool Wool box is an eco-friendly, biodegradable, light and strong waterproof cardboard box with integrated wool layers coming from discarded wool from the farm sector or regenerated wool from the textile industry. In this way, Cool Wool Box (which will be produced following a zero-waste circular economy production model) grants a superior insulation capacity to state-of-the-art solutions, while having a low carbon footprint and cutting down packaging, transport, and disposal costs. This project will allow our company to transition from pre-revenue to profitable business in just two years of commercialization, growing our t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Promoting Open Source in European Projects' in the context of a Seventh Framework call.

assistant: **Objectives**

Free/Libre/Open Source Software (FLOSS) is creating new R&D opportunities across Europe, particularly in an ICT context where projects require an adequate cooperation environment. Despite the numerous advantages of FLOSS as a cooperation model, however, most developed software faces a limited life cycle and applicability. The absence of a common platform where projects can publish their software - with reliable and trustworthy usage terms/conditions - creates adoption difficulties. As a result, software is re-invented within the ICT community, leading to duplication of effort and failed R&D opportunities.Adopting FLOSS paradigms will extend the lifetime and sustainability of ICT software, increasing contributions to and from the community. To achieve this vision it is necessary to: promote FLOSS for ICT projects, by removing existing obstacles, especially legal and business barriers; create a feedback loop for FLOSS usage in ICT projects that encompasses the EC and enables them to assess the true benefits of a FLOSS-driven model; enable long term exploitation of FLOSS through a sustainable model for ICT contributions.The PROSE proposal is a Coordination Action (CA) that targets these goals through a three-fold, complementary approach:(a) Create and manage a shared platform for FLOSS, capable of generating the required feedback loop;(b) Develop a training program that provides knowledge and learning about this shared platform, as well as legal and business aspects regarding the adoption of FLOSS;(c) Execute a dissemination program to increase awareness of the advantages of adopting a FLOSS-driven model in ICT projects.With these three coordination elements, the PROSE CA will increase the sustainability of FLOSS in ICT; thereby extending the reach of ongoing FLOSS efforts
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Reactions in Microdroplets Accelerated by Plasma' (REMAP) under Horizon Europe.

assistant: **Objectives**

Chemical reactions are normally conducted in bulk solution. In some cases, the rate of such bulk reactions is quite slow, limiting the throughput of a synthetic route. In recent years, a novel field of research based on microdroplet chemistry is emerging as an analytical tool for reaction monitoring, as well as a mean for accelerating chemical reactions. By using droplet chemistry, reaction rates can be increased by several orders of magnitude compared to the bulk counterpart. It is therefore beneficial to systematically investigate the reactivity of microdroplets and to understand the role of the underlying mechanism and individual parameters that can influence their reactivity (e.g., pH, temperature, concentration and surface effects). A better fundamental knowledge will make microdroplet reactions faster and allow for novel approaches to be developed. The goal of my research proposal is to achieve a broader fundamental understanding of microdroplet chemistry, and use this knowledge to investigate the novel field of plasma-microdroplets interaction, which is expected to open the doors for a completely novel chemical reactivity. The highly reactive species generated by plasmas will be allowed to react with the highly reactive surface of microdroplets. The possible outcome is a substantial increase in reactivity, promoting reaction pathways normally not significant in bulk or even droplets. By exploiting the unexplored field of plasma-droplets interaction, I plan to identify reaction pathways that can significantly increase reaction yields of high added-value compounds, aiming at more sustainable, efficient and competitive industrial synthetic processes, and at the possible conversion of existing waste products into chemicals which could still be useful for our society.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'HetERogeneous sEmantic Data integratIon for the guT-bRain interplaY'.

assistant: **Objectives**

HEREDITARY aims to significantly transform the way we approach disease detection, prepare treatment response, and explore medical knowledge by building a robust, interoperable, trustworthy and secure framework that integrates multimodal health data (including genetic data) while ensuring compliance with cross-national privacy-preserving policies. The HEREDITARY framework comprises five interconnected layers, from federated data processing and semantic data integration to visual interaction. By utilizing advanced federated analytics and learning workflows, we aim to identify new risk factors and treatment responses focusing, as exploratory use cases, on neurodegenerative and  gut microbiome related disorders. HEREDITARY is harmonizing and linking various sources of clinical, genomic, and environmental data on a large scale. This enables clinicians, researchers, and policymakers to understand these diseases better and develop more effective treatment strategies. HEREDITARY adheres to the citizen science paradigm to ensure that patients and the public have a primary role in guiding scientific and medical research while maintaining full control of their data. Our goal is to change the way we approach healthcare by unlocking insights that were previously impossible to obtain.


**Keywords:** Multimodal health data; federated networking infrastructure
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Colour Printing 7.0: Next Generation Multi-Channel Printing' in the context of a Seventh Framework call.

assistant: **Objectives**

We propose a training and research project within the Marie Curie Initial Training Network (ITN) call, led by Gjøvik University College (HIG), in collaboration with five full network partners and six associated partners from academia and industry throughout Europe. The project is entitled “Colour Printing 7.0: Next Generation Multi-Channel Printing” and addresses a significant need for research, training, and innovation in the European printing industry.Through our project, we will not only take the colour printing field to its next generation of technological advancement, by fully exploring the possibilities of using more than the conventional four colorants cyan, magenta, yellow and black, focusing particularly on spectral properties, but we will also train a significant new generation of printing scientists (seven ESRs and two ERs) who will most certainly be able to assume science and technology leadership in this traditional technological sector. The main variables in printing technology are the ink, the paper, and the marking technology employed by the printer. While many aspects of these are well known and extensively studied, there are four key areas of science and technology which future advances in multi-channel printing depend on:1.Spectral modeling of the printer/paper/ink combination2.Spectral gamut prediction and gamut mapping3.The effect of paper optical and surface properties on the colour reproduction of multi-channeldevices4.Optimal halftoning algorithms and tonal reproduction characteristics of multi-channel printingRelated to the above research areas are the need to have optimal methods for ink selection, and methods for the evaluation of reproduction quality. Together these areas form a large problem domain that cannot be addressed by a single manufa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Organic carbon sequestration and environmental change during the mid-Cretaceous: biogeochemical studies of outcrop pelagic sediments from the Vocontian Basin, SE France' (C-TEMP) targeting Sixth Framework.

assistant: **Abstract**

The mid-Cretaceous 'greenhouse' world, characterised by high atmospheric carbon dioxide levels (3-8 times the pre-industrial values), also experienced widespread deposition of marine sediments anomalously rich in organic carbon. This was due to the presence of oxygen-defficient conditions in the ocean and/or high fluxes of organic matter to the sea floor.The term oceanic anoxic events" (OAEs) has been coined in the literature to collectively describe such events. The Cenomanian/Turonian boundary interval (C/T, circa 93.5 Ma) records a classic example of an OAE, which resulted in one of the largest perturbations of the carbon cycle in Earth history. This event is revealed by large, positive carbon-isotope excursions in both inorganic and organic carbon worldwide, due to extensive sedimentary burial of organic matter.Unfortunately, complete C/T sedimentary records required for high-resolution studies are relatively rare and, when available, they commonly suffer from a number of limitations. Preliminary investigations of outcrop sedimentary rocks from the Vocontian Basin, France, has provided new potential for further research on the causes and consequences of the C/T OAE.We propose to undertake detailed, high-resolution studies on samples from the above location, using organic geochemical methods at a molecular level. These will allow advanced insight into this major episode of global change in the Cretaceous, with emphasis on the functioning of global biogeochemical cycles, possible feed-back mechanisms and, as a response, the evolution and extinction of different life forms.The proposed project will involve a close collaboration between a leading European Marine Research Institute (NIOZ, the Netherlands) and a promising scientist from Greece (Dr Harilaos Tsikos) with a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Club of Underground Storage, Testing and Research Facilities for Radioactive Waste Disposal - CLUSTER URL 2' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

The seminar planned in Mol from 27.09 to 28.09.2001 will address the R&D and demonstration projects running or planned in European URL's to stimulate further networking activities. Deep geological disposal is currently the most studied option for isolation high-level radioactive waste from man and his environment. URL's have been constructed with the aim to further characterise in situ candidate or potential host rocks (clay, salt, granite) and to test and/or demonstrate the technical feasibility of the respository concepts. They offer important opportunities for participation of research institutes from all Member States of the European Union. Beside a general overview of current and planned activities some projects will be described more in detail. A special session will address the approaches, capabilities and limitations of the models used in the respective projects for the EBS and their application in Performance Assessment.- To get an overview of the current and planned activities in URL's.- To discuss recent results of the major projects at URL's.- To discuss the application, progress and needs in modelling related to large scale in situ tests.- To stimulate further information exchange and international co-operation in the light of the EC recommendations to create the European Research Area (ERA), which in particular aims at Networking activities in Europe around common or shared research programmes.Underground research laboratories (URL's) offer important opportunities for participation of research institutes from all Member States of the European Union. Such international co-operation has been established around the HADES URL in the Boom Clay at Mol, Belgium, the Mt. Terri Project in Opalinus clay and the Grimsel Fels Labor in hard rock in Switzerland, the Ass