RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Evaluating physiological and environmental consequences of using organic wastes after technological processing in diets for livestock and humans' (SAFEWASTES) under Sixth Framework.

assistant: **Objectives**

This project aims at developing and evaluating consequences (physiological and environmental) of using various organic wastes (OW) from the food/feed industry after their technological processing/purification as upgraded, high added value products of preventive/therapeutic potency for livestock. In the context of phasing-out in-feed antibiotics for livestock within the EU, such post-processed industrial OW as fruits, vegetables, plant-based extracts would be of a great help to overcome a risk of uncontrolled gastrointestinal/metabolic disorders in the absence of in-feed antibiotics in 2006. Besides, novel high value added products should allow to minimise the development of resistances of pathogenic micro-organisms, which meets consumer expectations.This project is addressed towards meeting public demands and Community policy for healthy food (no risk of antibiotic resistance) being produced at a higher animal welfare standard. Moreover, it will improve European competetiveness in providing new, naturally purified OW as potential dietary additives/antimicrobials/functional compounds targeted for combating gastrointestinal/metabolic disorders and/or modulating the gut functioning with positive benefits for quantity/quality of consumable products from livestock. Besides, newly developed/purified OW should allow to reduce the environmental burden with the overproduction of methane and other potentially polluting/toxic compounds. This consortium comprises a multidisciplinary academic staff from the member and candidate states, as well as SMEs to generate new manpower in biotechnological processing/upgrading of organic wastes from the food industry, (bio/phyto)chemistry, nutrition, physiology, bacteriology, functional genomics, feed technology/ manufacturing, and environment
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'DevelopMent AnD application of integrated technological and management solutions FOR wasteWATER treatment and efficient reuse in agriculture tailored to the needs of Mediterranean African Countries' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Climate change and population growth are expected to exacerbate the water crisis of Mediterranean African Countries (MACs), where agriculture accounts for 80-85% of freshwater consumption. The aim of MADFORWATER is to develop a set of integrated technological and management solutions to enhance wastewater treatment, reuse for irrigation and water efficiency in agriculture in three MACs (Tunisia, Morocco and Egypt). MADFORWATER will develop and adapt to three main hydrological basins in the selected MACs technologies for the production of irrigation-quality water from drainage canals, municipal, agro-industrial and industrial wastewaters, and technologies for water efficiency and reuse in agriculture, initially validated at laboratory scale. Selected technologies will be further adapted and validated in four field pilot plants of integrated wastewater treatment/reuse. Integrated strategies for wastewater treatment and reuse targeted to the selected basins will be developed, and guidelines for the development of integrated water management strategies in other basins of the three target MACs will be produced, considering climate change, population increase and economic growth scenarios. The social and technical suitability of the developed technologies and non-technological instruments in relation to the local context will be evaluated with the participation of MAC stakeholders and partners. Guidelines on economic instruments and policies for the effective implementation of the proposed water management solutions in the target MACs will be developed. The project will lead to a relevant long-term impact in Egypt, Morocco and Tunisia in terms of increased wastewater treatment, wastewater reuse, food production and income in the agricultural and water treatment sectors, and d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Unravelling the architecture and the cartography of the human centriole' to be submitted under Horizon 2020.

assistant: **Abstract**

The centriole is the largest evolutionary conserved macromolecular structure responsible for building centrosomes and cilia or flagella in many eukaryotes. Centrioles are critical for the proper execution of important biological processes ranging from cell division to cell signaling. Moreover, centriolar defects have been associated to several human pathologies including ciliopathies and cancer. This state of facts emphasizes the importance of understanding centriole biogenesis.  The study of centriole formation is a deep-rooted question, however our current knowledge on its molecular organization at high resolution remains fragmented and limited. In particular, exquisite details of the overall molecular architecture of the human centriole and in particular of its central core region are lacking to understand the basis of centriole organization and function. Resolving this important question represents a challenge that needs to be undertaken and will undoubtedly lead to groundbreaking advances. Another important question to tackle next is to develop innovative methods to enable the nanometric molecular mapping of centriolar proteins within distinct architectural elements of the centriole. This missing information will be key to unravel the molecular mechanisms behind centriolar organization. This research proposal aims at building a cartography of the human centriole by elucidating its molecular composition and architecture. To this end, we will combine the use of innovative and multidisciplinary techniques encompassing spatial proteomics, cryo-electron tomography, state-of-the-art microscopy and in vitro assays and to achieve a comprehensive molecular and structural view of the human centriole. All together, we expect that these advances will help understand basic prin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'A CEMent harnessing EARTH for a sustainable built environment' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

In the pursuit of a more sustainable future, green concrete stands out as a crucial innovation in the construction industry. Cement, the primary ingredient in concrete, is essential for its production but is responsible for approximately 9% of global CO2 emissions. Rapid urbanization and infrastructure development have further amplified environmental concerns, particularly regarding carbon emissions. The stringent targets set to combat climate change and achieve carbon neutrality by 2050 have driven the industry to seek effective solutions for reducing its carbon footprint.The EARTHCEM project is at the forefront of this transformation, exploring the potential of Limestone Calcined Clay Cement (LC3) to revolutionise the industry. By incorporating locally sourced clay materials and reducing clinker use, the project aims to minimise environmental impacts while optimising resource and energy efficiency. To ensure the durability and performance of LC3 under real-world conditions, the project will employ advanced accelerated testing methodologies, simulating long-term environmental exposure in shorter time frames. These tests will validate the mechanical properties, durability, and long-term performance of LC3, ensuring that it meets the rigorous demands of large-scale infrastructure applications. By providing the industry with a comprehensive and robust set of data, EARTHCEM will help to mitigate uncertainties related to the material’s behaviour over time, enhancing its appeal for broader adoption in construction.This initiative represents a significant approach toward sustainable development, aligning infrastructure advancements with ecological and economic resilience. Through innovative research, practical solutions, and rigorous accelerated testing, EARTHCEM is paving th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Prevention of chromium(vi) formation by improving the tanning processes'.

assistant: **Concept**

Trivalent salts of chromium are the tanning agents used mainly in European leather production. The trivalent state is considered to be non-toxic but a high degree of toxicity is attributed to chromium (VI). The possible presence of chromium (VI) in leather constitutes a problem of paramount importance for the European tanning industry from both the social and environmental viewpoints. In given situations traces of chromium (VI) are detected. The problem is complex because it is possible to detect chromium (VI) in manufactured leather, which has not been deliberately treated with compounds of this oxidation state. The aim of the project is to establish the most suitable conditions that allow the production of skins/hides that are free of chromium (VI), even during their useful life in contact with environmental agents such as heat and light. It is believed that this objective may be achieved improving the tanning processes by introducing protective measures, which prevent the oxidation of chromium to its hexavalent state.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Evaluation of methods for prediction of conformation of loops, and their application to the modelling of 3-d structure of proteins' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

Research objectives and content The aim of the proposed project is to up-date the loop-data base and to evaluate the loop selection procedures. Loop regions are non-repetitive conformations connecting regular secondary structures. They are the hardest to model and most prone to errors. However the accurate modelling of loop regions may be crucial as they are often involved in molecular recognition-processes. In order to model loops it is necessary to select protein fragments from a wide database of all known protein structures, and not just members of the homologous family. Generally they are selected using a geometric filter. When the fragments are sought out side the family, a large number of segments usually results posing the problem of selection of the most appropriate fragments. Two powerful methods have been developed: the fragment ranking method (Topham et al, 1993) and the SLOOP method (Rufino et al, 1997). Both methods when individually used are useful in the selection of appropriate fragments for loop modelling. However, it is necessary to evaluate the performance of both. For this we are proposing to carry out an exhaustive study on a large number of loop sequences from proteins of known-three dimensional structure. We also propose to derive at a new scoring scheme in which the contributions from each method are appropriately weighted. Finally, we will apply this procedures to the model of unknown three-dimensional structure proteins. Training content (objective, benefit and expected impact) The objective of the proposal is to achieve a deeper knowledge in loop-prediction. As loop regions are the most difficult to model, any improvement in the prediction of these regions will be worth. Thus, if we develop a new scoring scheme, it will be a useful tool for pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Human-mimetic approach to the integrated monitoring, management and optimization of a symbiotic cluster of smart production units'.

assistant: **Objectives**

Improvements of the overall sustainability of process industries from an economic, environmental and social point of view require the adoption of a new industrial symbiosis paradigm - the human-mimetic symbiosis - where critical resources (materials, energy, waste and by-products) are coordinated among multiple autonomous Production Units organized in industrial clusters.SYMBIOPTIMA will improve European process industry efficiency levels by: (a) developing a cross-sectorial energy & resource management platform for intra- and inter-cluster streams, characterized by a holistic model for the definition, life-cycle assessment and business management of a human-mimetic symbiotic cluster. The platform multi-layer architecture integrates process optimization and demand response strategies for the synergetic optimization of energy and resources within the sectors and across value chains. (b) Developing extensive, multi-disciplinary, modular and “plug&play” monitoring and elaboration of all relevant information flows of the symbiotic cluster. (c) Integrating all thermal energy sources, flows and sinks of the cluster into a systemic unified vision, as nodes of smart thermal energy grid. (d) Taking into account disruptive increase of cross-sectorial re-use for particularly impacting waste streams, proposing advanced WASTE2RESOURCE initiatives for PET.The development of such a holistic framework will pave the way for future cross-sectorial interactions and potentialities. Furthermore, the adoption of available LCSA and interoperability standards will grant easy upgradability of legacy devices and a large adoption by device producers. Modularity, extendibility and upgradability of all developed tools will improve scalability and make the SYMBIOPTIMA approach suitable both at small
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Large-Volume Electron Spectroscopy for Neutrino Mass Measurement' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Neutrinos, assumed massless in the Standard Model of particle physics, must have masses to explain the observation of neutrino oscillations. However, the absolute neutrino mass scale remains elusive. Laboratory measurements using tritium beta decay provide the most direct and model-independent means of determining neutrino mass. Yet, current experiments utilizing molecular tritium sources face fundamental sensitivity limits. This project aims to develop a groundbreaking resonant cavity detector capable of performing neutrino mass measurements with unprecedented precision.Within this project, I will develop and build a resonant cavity, laying the foundations for the next-generation neutrino mass measurement. The detector will simultaneously serve as a high- volume trap for neutral atomic tritium and as a detector for beta decay electrons. Utilizing cyclotron radiation emission spectroscopy (CRES) in a cubic-meter-scale cavity, this technique promises to significantly enhance sensitivity by resonantly amplifying the power of emitted radiation from trapped electrons, which has never been demonstrated. This will increase the CRES-sensitive volume by five orders of magnitude and reduce the power threshold for signal detection by four orders of magnitude, enabling high-precision measurements that could decisively determine the neutrino mass scale.Beyond its critical role in advancing neutrino physics, this project will contribute innovative tools and methodologies to the ultracold atom community and other precision measurement fields. By overcoming existing technological barriers, this detector paves the way for revolutionary advancements in our understanding of fundamental particles.


**Keywords:** neutrino mass, neutrino properties, detector development
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Discovery platform for novel catalysts' (NOVOCAT) targeting Sixth Framework.

assistant: **Abstract**

This project focuses on the transfer and integration of distinct but highly complementary areas of research competence in a SME and an academic Institute. The Academic host's expertise lies in the area of the development of biotechnological routes to chiral molecules. The Industry host's expertise lies in the area of the development homogeneous catalytic routes to chiral molecules via High Throughput Experimentation (HTE).The aim is to build a long-term strategic partnership, in which for the SME its core discovery platform can be enhanced greatly to increase its competitiveness, whereas the academic scientists will learn how to work in a commercial environment and acquire knowledge about the market. In this project 3 scientists, to be recruited from across Europe at the University or at the SME, will be seconded to the other partner and work under the supervision of experienced scientists for a period of up to 24 months, before they'll return for (at least) one year to further transfer and develop the knowledge acquired there.This scheme will allow Transfer of Knowledge in three directions:-from Academia to SME-from SME to Academia-from the various countries where the recruited scientists came from to the project partners.For scientists, especially if they'd originally came from the New Member States, this may make a big difference as they acquire broad knowledge beyond purely scientific expertise.The SME will benefit from an enhanced technology platform, thereby increasing its competitiveness and the academic centre will obtain a strategic industry relationship and direct experience with commercialization. The project addresses various major strategic objectives of the European Commission - most notably the empowerment of world-class research and development in SMEs,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Immunoprevention and immunotherapy of SARS infection' (SARSVAC), addressing dissemination and exploitation.

assistant: **Impact**

The 114 days-lasting epidemic wave of the Severe Acute Respiratory Syndrome (SARS) swept 30 countries, sickened a reported 8422 people, left 916 patients dead in its wake, and almost completely paralysed Asia's economy. Aggressive quarantine measures and rising summer temperatures successfully terminated the first eruption of SARS and provided at least a temporal break, which allows us to consolidate what we have learned so far and plan for the future. Thus, this project was prepared in response to urgent medical and societal needs for ¡mmunopreventive (vaccination) and immunotherapeutic measures for the Severe Acute Respiratory Syndrome (SARS). An integrated strategy for developing effective vaccines and for establishing effective therapeutic treatment will be developed. The strategy for vaccine development will follow two parallel approaches: 1. the preparation of a classical inactivated vaccine (as already done for other coronaviruses), 2. the definition of potential antigens and T/B protective epitopes through the study of SARS-CoV derived virus-like particles (VLP), pivotal to the understanding of SARS-CoV morphogenesis and virion maturation. The immunotherapeutic strategy will rely on development and validation of neutralising human antibodies to SARS-CoV. Under this project, academia experts in immunology, vaccinology, and molecular biology have joined forces with industrial vaccine production experts, in order to develop preventive and therapeutic measures for SARS'.