RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Translational Control by Molecular Chaperones: The Unexplored Mechanisms Coordinating Protein Synthesis and Proteostasis in Health and Genetic Reprogramming' (CHAPEROME) targeting Horizon Europe.

assistant: **Abstract**

CHAPEROME aims to establish a new concept in which molecular chaperones regulate central aspects of mRNA translation in human cells under physiological conditions, in response to proteotoxic stress, and during cellular differentiation. Recent findings indicate that the folding of translation factors relies on specific chaperone proteins to achieve their functional states. We hypothesize that chaperones play a pivotal role in aligning translation rates, efficiency, and mRNA selection with the cell’s proteostasis needs, thus acting as folding sensors that link protein synthesis to cellular demands. Testing this hypothesis requires collaboration among experts in translation, nascent chain folding, and chaperone mechanisms. Establishing this new concept for regulation of translation involves a comprehensive identification of chaperone dependencies of translation factors, which will reveal how chaperone networks control their functionality and impact translation rate and efficiency (Aim 1). We will elucidate the mechanisms by which chaperones and cofactors regulate elongation rates through interactions with nascent protein chains and translation factors, showing new connections between translation and protein folding under physiological conditions. Inducing proteotoxic stress to trigger chaperone overload will reveal the importance of chaperone regulation of translation (Aim 2). Finally, we will examine the new concept in the context of cellular differentiation, to understand how translation and chaperone networks adapt to drastic changes in cell type-specific proteome needs. This will provide novel insight into the plasticity of the translation-chaperone regulatory systems (Aim 3). This interdisciplinary and synergistic effort will reveal new key principles of translation r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Revealing the adaptive internal organization and dynamics of bacteria and mitochondria' (Piko) targeting Horizon 2020.

assistant: **Abstract**

Bacteria cells appear to be less complex than our own cells -- yet they are better able to survive harsh conditions. Typically ~1 micron in size, they lack motor proteins; thus, they rely on fluctuations for intracellular transport. Bacteria in the environment often face starvation and exist in a non-proliferating quiescent state, which promotes antibiotic resistance and virulence. Entering quiescence, the bacterial cytoplasm displays signatures of the colloidal glass transition, with increasingly slow and heterogeneous diffusion. Also important for fitness during starvation is the formation of storage granules up to hundreds of nanometers in size. The complex state behavior of the bacterial cytoplasm is therefore important for their survival, but the physical nature of each of these processes is poorly understood. Our own cells are typically tens of microns in size and contain organelles including mitochondria, which originated from ancient bacterial endosymbionts. But little is known about the transport properties of the mitochondrial matrix, or how it responds to changes in mitochondrial membrane potential or energy production. The goal of this project is to elucidate the organization and dynamics of the bacterial cytoplasm and the mitochondrial matrix. A major obstacle to studying the interior of bacteria and mitochondria is the relevant length scales, which lie below the diffraction limit. Furthermore, to observe and quantify their adaptive response, many cells must be measured. Our strategy to overcome both of these technical challenges is to use high-throughput super-resolution fluorescence microscopy. We have developed new microscopes, capable of capturing thousands of super-resolved cells in each experiment. We propose to translate these developments to dynamic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Microelectronic opto mechanical systems in campania felix' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

The Research Institute on Electromagnetics and Electronic Components (IRECE) is located in the wonderful bay of Napoli. The Department of Electronic Components is a small yet dynamic research group involved in the modeling, design, fabrication and test of silicon-based optoelectronic devices for communication and sensing. The scientific level of such activity is witnessed by the over 100 papers published in the last few years. Scientists at IRECE (35 yrs. old on average) come from various fields (electrical, electronic, mechanical and material science engineering, physics). They all have responsibilities of one or more research topics, and have plenty of space for organizing their own work. With the recent acquisition of new technological facilities (PECVD, RIE, sputtering, RTA, e-beam evaporator , a small clean room for photolithography and wet etching) IRECE now aims at starting a full in-house activity in the rapidly expanding field of Micro-Opto-Electro-Mechanical Systems. Of particular interest to the group is the development of innovating active optoelectronic devices including moving membranes and cantilevers. The group therefore seeks two post-doctoral fellows having hands-on experience in the design/fabrication of MEMS. Extensive clean room process experience (either bulk or surface micro machining and/or thin film deposition and/or wet/dry etching) is desired. Basic knowledge of the design principles and fabrication techniques of integrated optical devices would be appreciated. The fellows are expected to take the responsibility of one or more of the named technological facilities, and him/herself to make proposals for new research topics. The staff will offer the fellows a warm and friendly welcome within their group and the full participation to all of their
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Attractive, Acceptable and Affordable deep Renovation by a consumers orientated and performance evidence based approach' (TripleA-reno).

assistant: **Innovation**

TripleA-reno will focus on following market barriers for deep renovation: 1The renovation market is top-down and supply-driven, with a mismatch between the offered products and packages and the end-users’ requirements 2 There is no view on the total performances in practice (energy, indoor environmental quality, health and well-being), as well as a solid quality control of the renovation process 3 After the renovation process there is a lack of data on the real building performance in practice, on energy, IEQ and health. Many European projects have addressed these barriers. The overall aim is to make acceptation and decision making on deep and nZE renovation attractive for consumers and end-users. This by clear, unambiguous and meaningful information and communication on real, proven performances on energy, Indoor Environmental Quality and personal health in practice, strengthened by consumer centred business models. TripleA-reno will achieve this aim by developing an open end-users centred gamified platform for validation and community building, The objectives are:1. To foster new consumer and end-user centred business models, using evidence based performances that facilitate decision-making. 2. Improving performances of deep renovation by enhanced quality control, supported by targeted CPD and training, 3. Providing consumers and end-users of deep renovation projects with attractive, understandable and personalized information of realised real performance. 4. To demonstrate the benefits and evidence based solutions in live demonstration cases.  5. To roll out the results on a wider European scale by the in Triple A-Reno involved European interest groups and umbrella associations
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Investigation of direct and mediated bioelectrochemistry of galactose oxidase and related enzymes. the application of the biosensors for measurement of clinically important metabolites.' (1998-2002).

assistant: **Innovation**

The bio electrochemical investigation of the enzymes will be used to optimise the construction of amperometric biosensors. The biosensors will be employed for detection of clinically important compounds such as markers of cancer and neurological diseases
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Towards Sustainable Mobility for people in urban areas' to be submitted under Sixth Framework.

assistant: **Abstract**

The objectives of VISIT 2008 are: improved urban air quality, create a sustainable, safe and flexible traffic system that improves the quality of life in Malmo and Tallinn. It will cut the current trend of increased use and ownership of cars, promote sustainable alternatives and stimulate efficient and clean city distribution of goods. VISIT 2008 contains 20 demonstration measures, which will directly lower the hazardous emissions from city traffic. In the long run it will create a modal shift towards public transport, cycling and car-sharing. The strategy is to combine a set of measures to develop an intelligent, sustainable and intermodal city traffic that makes it possible to live an active life independently of use and ownership of private cars. The measures are divided into 8workpackages following the policies of the Civitas programme."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Cryptophane-Enhanced Trace Gas Spectroscopy for On-Chip Methane Detection' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

Sensitivity of on-chip gas sensors is still at least 2-3 orders of magnitude lower than what is needed for applications in atmospheric monitoring and climate research. For optical sensors, this comes as a natural consequence of miniaturization: sensitivity scales with interaction length, which is directly related to instrument size. The aim of this project is to explore a new concept of combined chemical and spectroscopic detection for on-chip sensing of methane, the principal component of natural gas and a potent climate forcer.The sought-after sensitivity will be achieved by pre-concentrating gas molecules directly on a chip surface using cryptophanes, and subsequently detecting them using slow-light waveguides and mid-infrared laser absorption spectroscopy. Cryptophanes are macromolecular structures that can bind and thus pre-concentrate different small molecules, including methane. Spectroscopic detection of methane in a cryptophane host is an absolute novelty, and, if successful, it will not only contribute to unprecedented sensitivity enhancement, but will also address fundamental questions about the dynamics of small molecules upon encapsulation. The actual gas sensing will be realized using evanescent field interaction in photonic crystal waveguides, which exhibit both large evanescent field confinement and long effective interaction pathlengths due to the slow-light effect. The waveguide design alone is expected to improve the per-length sensitivity up to 10 times, while another 10 to 100-fold sensitivity enhancement is expected from the pre-concentration. The targeted detection limit of 10 ppb will revolutionize current methods of atmospheric monitoring, enabling large-scale networks of integrated sensors for better quantification of global methane emissions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Development of a Closed Loop Flow Control Algorithm for Wing Trailing Edge Flow Control Including Experimental Validation in Two Low Speed Wind Tunnel Tests', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Smart Fixed Wing Aircraft (SFWA) aims to develop and test passive and active flow control technologies to improve the high lift performance of a wing. The purpose of this research is to develop and demonstrate a closed loop flow control to minimise the separation on a trailing-edge flap. The active flow control will improve the aerodynamic performance by delaying the trailing-edge separation on a single element trailing-edge flap. The flow control will be pulsed blowing applied near the leading-edge region of the flap. The pulsed blowing will be through spanwise segmented slots. A closed loop flow control system will be designed to demonstrate flow control on a mid-scale wind tunnel model. The Topic Description calls for two directions of closed loop flow control methods. The first is a pre-modelled approach which would allow the calibrating of the algorithm. This algorithm development will be devoted for future use in flight test activities. The second method is an adaptive algorithm, which will be adjusted by a “learning-by-doing” system. This approach will be demonstrated in mid-scale wind tunnel tests.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Mastering bioprocess Integration and intensification across scales'.

assistant: **Innovation**

BIOINTENSE is directed at addressing the challenges of low productivity and process intensity frequently hampering the implementation of bioprocesses in industry. For the future of the next generation of chemical processes in Europe it provides the opportunity not only to address intensification but also to enable this in a rapid manner. BIOINTENSE will make use of µ-technology to develop economically feasible intensified processes by integration of separation and process control, and to create tools to speed up the characterization and assessment of different process options and technologies and biocatalysts for increased process intensity. A strong focus lies in increasing the scale of biocatalytic and cascade reactions and to improve the fundamental factors that affect the economic feasibility. Both numbering up and scale-up methodologies will be tested.The BIOINTENSE consortium is ideally suited to address the challenges in KBBE.2012.3.3-03 and to meet the objectives, as it spans across disciplines, academia and industry: SMEs with a strong technology base in the areas of integrating separation in bioprocessing, biocatalyst development, immobilization, μ-reactor fabrication, and on-line monitoring will ensure top of the line industry focused research with a strong focus on scale-up and implementation.There is an urgent need for these challenges to be overcome to move towards a European Knowledge Based BioEconomy to exploit the environmental savings and economic potential if such bioprocesses were in place. Building on the recent advances in molecular biology, the time is now right to develop the necessary process engineering methodologies and implementation strategies to unlock the full potential of bioprocesses.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Promotion of rural museums and heritage sites  in the vicinity of European pilgrimage routes'.

assistant: **Innovation**

The rurALLURE action aims to leverage the state-of-the-art in information technologies in order to promote rural museums and heritage sites in the vicinity of major European pilgrimage routes. The goal is to foster symbiosis between the rural environment and the pilgrimage routes, so that the ongoing investment in the latter permeates to the nearby rural areas and, the other way round, the cultural experience of the pilgrimage is enriched by the vast cultural heritage that most often goes unnoticed. rurALLURE will connect cultural heritage collections and venues to present Europe’s cultural heritage in the wider historical and geographical context, leveraging the role of museums in preserving and managing cultural heritage, and collaborating with national and transnational associations to develop and promote cultural tourism. It will also foster sustained cooperation between museums and heritage sites to increase European public interest, cultural tourism and the innovation potentials of these institutions for heritage sciences and the cultural and creative sectors. Finally, it will conduct work to identifying gaps and obstacles, as well as best practices and fields where research and innovation can develop new solutions for successful cooperation.


**Keywords:** Cultural heritage,  rural Europe,  pilgrimage routes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Electrodeposited Chalcopyrite thin film solar cells: High efficiency Limits and Losses Evaluation'.

assistant: **Objectives**

This project concerns New and Advanced Concepts in Renewable Technologies. It is relevant to FP6 objective Research Development and validation of thin -film PV technologies with higher efficiency cost ratio. The field of study is thin film solar cells manufactured by novel low cost methods. It adopts an interdisciplinary approach from two leading European scientific institutions. It is proposed to increase solar cell efficiency in the II-VI materials field by:- Flexible and quantitative modelling optimisation from a knowledge based perspective based on characterisation on a nanometre scale. This will develop a quantitative understanding of light and dark currents taking materials issues specific to this system into account down to the grain size scale.- Extrapolation of the knowledge to improved designs. These will primarily consist of changes to the band structure of the cell in order to maximise photocurrent, and minimise the trap dominated dark current by manipulating carrier density profiles in the depletion layers.- Increase efficient use of light by using light trapping techniques. In turn these relax requirements on layer thickness required to absorb incident light, and consequently relax the requirements on minority carrier transport. This leads to solar cells more tolerant of imperfect material, of particular interest in polycrystalline material.- Implement innovations in real thin film polycrystalline devices (chalcopyrite type) produced by low cost methods (electroplating) in which the host laboratory has a recognised experience.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Stand-alone power supply saving low-speed fluid energy available around us', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The project is about designing, manufacturing and marketing a range of stand-alone power supply products based on pico-turbines able to efficiently produce on-line and deliver the few tens to hundreds of watts needed by the process and quality control equipment of the water supply networks.Indeed, so as to limit the Non-Revenue Water (35% NRW in average worldwide ) and to reach the expected service quality, sensors as well as regulation systems and signal transmitters are increasingly installed at the innumerable junctions of the water distribution networks.Beyond those needs, there are several similar industrial stand-alone power needs which can be fulfilled by our breakthrough technology, like for industrial fishing monitoring equipment, irrigation monitoring systems, sailboat on-board safety and comfort equipment or weather marine station and buoy networks equipment, all being of global reach.Thanks to its partnerships with public research labs (Polytechnique Grenoble, CNRS) and experts (Prof. M. Jufer, EPF Lausanne), as well as 3 years of technical development, Save Innovations designed its first innovating pico-turbine, which is intrinsically waterproof, simple (5 main components), requires no specific maintenance and produce at flow speed as low as 0.5m/s. 4 Patents are published, and 5 new patents have been applied.A first set of prototypes have been successfully tested in a relevant environment. Feasibility within the breadth of the water network requirements as well as product range analysis is now needed before heading to the standard product development and industrialization (will trigger a phase-2 request)