RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'DYNamic feedbacks of climate impacts on current Adaptation and Mitigation Investment Choice' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

This projects proposes a novel framework to modeling the economic consequences of climate change impacts and the induced policy responses, in terms of both mitigation and adaptation strategies at regional scale.To accomplish this task, state-of-the-art IAMs will be modified to include (1) The causal chain between sectoral and regional economic activity and emissions; (2) The climate change feedbacks induced by temperature increase on the different economic sectors and regions; (3) The optimal policy response in terms of mitigation; (4) The optimal policy response in terms of regional and sectoral adaptation.This is a challenging task because of the different nature of adaptation and mitigation and the need of combining optimization with a regional/sectoral detail in a general equilibrium framework, but feasible. Integrating adaptation strategies in an optimization framework will allow to quantify adaptation needs under different mitigation and climate change damage scenarios and to study cross-sectoral spillovers and interactions between the two policy responses, with a sectoral resolution. The project proposed is intrinsically interdisciplinary, requiring a clear understanding of the scientific basis for estimating climate impacts and the skill to combine rigorous empirical analysis with judgment and assumptions in order to cope with incomplete or incommensurate data. The work will be articulated in three main activities: (1) Model development and coding; (2) Data gathering; and (3) Numerical exercises.The expected impact of this research is high because it will develop a roadmap that will serve the future research on induced regional adaptation in a macroeconomic framework.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Characterization of drought tolerance related mechanistic traits in sorghum related to water transport' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Sorghum is a drought tolerant cereal crop, grown extensively by smallholder farmers in West Africa. It is expected to become increasingly important to crop production in the Sahel, and grow as part of Europe’s grain portfolio as incidences of drought become more frequent. Identifying drought tolerant varieties and what traits confer drought tolerance in sorghum is of great importance to food security both in the Sahel and across the world. The SorghEau project will investigate drought tolerance in sorghum, to uncover the mechanistic basis for this trait, the role of adaptive plasticity in the drought response, and the genetic control of traits relating to drought tolerance. The main focus of this will be investigating vascular anatomy, particularly the metaxylem and its effect on physiology and water use. Using diversity populations in West Africa and Europe will capture data on the vast majority of global genetic diversity, as well as highly agronomically relevant elite lines. This will facilitate gene discovery, and by investigating a highly drought tolerant crop with a known diversity for this feature, we expect significant findings. I will use this data to identify a vascular trait with a role in drought tolerance, and select lines of interest and parental candidates for mapping populations contrasting in this trait. I will investigate plasticity through controlled drought experiments to characterize the role of vascular traits in the drought response. I will then use this data to identify a candidate trait, and conduct genetic analysis to identify associated QTLs, and use gene expression analysis to uncover the molecular mechanism for regulation of this trait. This work will develop my skills in conducting field trials, anatomical analysis, and plant physiological
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'V is for Vegetable: Applying Learning theory to increase liking and intake of vegetables' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

It is now well-established that consuming fruits and vegetables promotes health and well-being.  In particular, intake of fruits and vegetables protects against cancer and is associated with lower levels of obesity.  Consumption of a diet rich in fruits and vegetables is predicted by the extent to which these foods are liked.  However, vegetable intakes remain relatively low, especially in children.  Establishing preference for vegetables early in a child’s development provides the best opportunity to enhance intake and to promote preferences which will last throughout life.  Most children in Europe fail to consume recommended 5 per day portions of fruits and vegetables and many fail to meet minimum recommendations to eat just one portion of vegetables each day. Therefore, this proposal has three main aims: to compare different methods of introducing complimentary foods in member states which best predict liking of vegetables in the first year of life; to develop and test an optimal weaning strategy to promote vegetable acceptance in infants; and to increase liking and intake of vegetables in children aged 4-5 years using flavour-flavour and flavour-consequence learning.  The main outcomes of this research programme are the development of a weaning strategy with an emphasis on early and sustained exposure to vegetable flavours; identification and development of new products to facilitate liking for vegetables and preparing an evidence-base for enhancing intake of vegetables in school age children.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Control of defects in TIG welds by use of a top face sensor system' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

A wide ranging survey of SMEs showed a need to reduce fabrication flaws associated with welds. An in-process sensing technique would significantly help fabricators control their welding process and reduce weld flaws. At present sensors that monitor the weld from the same side as the weld torch, known as top face sensors, do not meet industry requirements as they cannot compensate for all variations that lead to defective welds. This project will develop a top face sensor capable of controlling TIG welding conditions to produce acceptable welds in materials of between 1 mm and 3mm thickness. An effective system would be attractive to industry as it is more practicable and economic than sensing from the back of the weld. An innovative approach of combining two complementary sensing techniques will compensate for all the variations of material and joint condition. Welding control and sensing technology coupled with modelling and empirical assessement will be used to develop and evaluate a prototype system capable of working in industrial environments.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'AURASME' (AURASME) under Horizon 2020.

assistant: **Objectives**

The EURORAA consortium is committed to stimulating high potential SMEs to enhance their innovation capacity and their managerial practices, in order to maximize their smart, sustainable and inclusive growth. The AURASME project is a subset of the COSME EURORAA consortium, based in the Rhône-Alpes and Auvergne regions in France. An integrated coordination within the existing activities in the work program of the EURORAA consortium is ensured. The partners involved are: Partner 1 (coordinator) CCIR Rhône-Alpes, Partner 2 ARDI Rhône-Alpes and Partner 4 CCIR Auvergne, so only Partner 3 (ERAI) of the consortium is not involved in this specific activity. Host organizations of the AURASME project have an expertise in key factors for the successful implementation of this activity: support of innovation projects, in particular within the framework of European projects; good knowledge and experience in European programs for SMEs; experience in promoting and supporting different management systems within SMEs (quality, security, environment, performance…); wide approach to several key aspects of innovation system and good knowledge of the high growth potential SMEs located in the Rhône-Alpes and Auvergne regions. The general objective of this proposal is to bridge the gap of lacking innovation management capacities within the targeted SMEs located in Rhône-Alpes and Auvergne regions, in order to maximise the economic impact of ambitious innovation projects at European and International level. The work program is strictly focused on the objectives described in the call for proposal and on the implementation of the two required service packages: Key Account Management and Enhancing Innovation Management Capacity. The Work Programme describes the implementation of these two packages
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Development of a APP- - Secretase inhibitor as a potential drug and diagnostic tool'.

assistant: **Innovation**

Aging of the popoulation by increasing life expectancy is making the problem of age-related dementia increasingly important. Senile dementia is becoming a serious problem not only for family members including the patient but also for modern society. the existing drugs have been effective only for the complicated symptoms of related diseases. Hence, nex drugs effective for the essential pathology are required. Since 1990 the prime proposer has developed different types of highly effective compounds inhibiting proly endopeptidase (PEP), on of the putative key enzymes inducing the senile plagues formation. Two initial patent have been filed. The main goal of the research proposal is to tailor our already in vitro powerful inhibitors to be useful diagnostic and therapeutic compounds in vivo and clear the way for development of marketable drugs out of this invention. The following main research tasks will be approached on the molecular, cellular, physiological and behavioral levels: - elucidation of the molecular structure of brain PEP and their catalytic properties - investigation of the neurofunctional consequences of an inhibition/lack of PEP (application of highly effective inhibitors, antibodies and antisense oligonucleotides) - study of the physiological effects of sequence modified of neuroactive peptides and PEP inhibitors on long-term potentiation in vitro and in vivo - developing of organ and tissue-senstive inhibitors of PEP - pharmacokinetic and pharmacodynamic studies on PEP inhibitors To investigate the functional role of proline-specific peptidases on molecular, cellular and physiological level needs the combination of European skills and knowledge in neurobiology. Since about one third of the population in the age of 65 is suffering onset of Alzheimer's disea
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Towards observation-constrained UNderstanding and prEdicting of tropical Wetland mEThane emissions' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Tropical wetlands dominate wetland methane emissions globally and play a vital role in recent surges of atmospheric methane. Despite the importance of tropical wetland methane emissions in global methane budgets and future climate change, current knowledge about their magnitude, distribution and variations remains highly uncertain, which impedes effective climate strategies and actions. Through a synergy of biogeochemical (“bottom-up”) and atmospheric (“top-down”) methodologies, I propose the project TUNEWET (Towards observation-constrained UNderstanding and prEdicting of tropical Wetland mEThane emissions) to constrain tropical wetland methane emissions and their responses to climate change by integrating multiple data streams and modelling tools. I will carry out this research with Prof. Guy Schurgers at the newly founded Global Wetland Center (GWC), University of Copenhagen (UCPH). This project will gain new insights into the key processes regulating tropical wetland methane emissions and help resolve the largest uncertainty source in the global methane budget, thereby supporting science-based climate mitigation strategies.


**Keywords:** tropical wetland, methane emissions, climate change, flux upscaling, atmospheric methane inversion
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'The space and time aspects of b-globin gene transcription', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Research objectives and content  This project aims to analyze the spatial and replication aspects of the regulation of beta globin gene expression and will be focused on two questions: the restoration of transcription after cell division and the spatial distribution of the globin genes in the nucleus of transgenic mice. In particular existing transgenic mice will be used to search for a mitosis 'memory protein' and the spatial distribution of the locus in mice that either contain a normal globin locus or one that is subjected to position effects. In addition a novel beta globin locus will be constructed in transgenic mice to address contacts between distant regulatory regions and the genes. At present almost nothing is known about these parameters in vertebrate cells in vivo. The beta globin locus has been studied in great detail and the existing resources in beta globin transgenic mice and novel FISH technology offer an excellent opportunity to start addressing the spatial and temporal aspect of gene regulation in mammals. Training content (objective, benefit and expected impact)  I will obtain training in homologous recombination cloning, genetic manipulation of mice, DNA and PNA based FISH technology, protein based fluorescence technology and 3D analysis technology including confocal microscopy. Links with industry / industrial relevance (22) None are foreseen at the moment.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'High resolution x-ray detector for food quality control' in the context of a Fifth Framework call.

assistant: **Objectives**

The aim of the proposal is the implementation of an innovative High Resolution X-Ray Detector for on-line identification of pits, bugs or internal defects (bruises or frost damage) after the fruit pitting process or immediately before the packaging process of food products. In particular, in the present project, a prototype for on-line detection of residual pits (or pits fragments) in olives or cherries will be developed, because of the wide market of this sector in Europe. The X-Ray technology was individuated by previous tests because it allows a non-invasive and safe detection, as well as a good speed of processing. At present, X-ray applications in food processing only allow the detection of metals and foreign objects with strong difference of density with the product, but the identification of bodies with very little difference of density, as the case of pits and bugs in fruit, proposed in the present project, is a still not solved issue coming from the food processing sector.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'ATLAS: An international trial of tamoxifen duration', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

In 1995, about 850.000 new cases of breast cancer were diagnosed worldwide. In Europe alone about 200.000 women developed the disease and about half will die from breast cancer. As breast cancer is so common, establishing reliably whether a new approach to treatment could improve survival just moderately could save thousands of lives worldwide if the treatment is widely available and if it is of benefit to a large proportion of women who develop the disease. The worldwide overview by the Early Breast Cancer Trialists' Collaborative Group of randomised trials of tamoxifen in women with early breast cancer demonstrated a moderate but highly significant improvement in 10-year survival with tamoxifen. Indirect comparisons of trials assessing different tamoxifen durations suggest that more prolonged treatment confers a greater survival benefit and preliminary results from direct comparisons of different tamoxifen durations support the evidence in favour of longer treatment.However, there is insufficient randomised evidence of the risks and benefits of different durations of treatment. Further randomised trials involving several tens of thousands of women with long-term follow-up are required before any additional benefit from longer treatment can be detected or refuted reliably. Such large numbers requires collaboration throughout Europe and beyond.ATLAS (Adjuvant Tamoxifen: Longer Against Shorter) is an international megatrial which aims to recruit some 20 000 women worldwide and thereby to provide definitive evidence on the optimal duration of tamoxifen treatment. The trial uses a pragmatic design for randomisation and any woman who has been on tamoxifen for some years, usually at least 2 years, for whom there is uncertainty about whether to stop or continue tamoxifen, is
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'DIagnosis tOol Based on the measurement of molecular interactions' in the context of a Fifth Framework call.

assistant: **Objectives**

This project intends to take advantage of the mechanical properties of micro- and nano-mechanical structures (cantilevers) to measure molecular (ligand-receptor) interactions. Such measurements would have applications in fields such as health and clinical diagnosis, environmental monitoring, detection of illicit materials and food safety. Within those application areas, the project will concentrate on the clinical diagnosis field, with two specific applications: the detection of tumour-associated protein and the detection of viruses. These applications have been selected because the partners already have specific know-how in those areas.Objectives:The main objectives of the project are:i) to develop versatile, inexpensive, and easy-to-use diagnostic tools for health, environmental and other applications based on the measurement of molecular interactions (ligand-receptor itneractions) by integrated micro and nano-cantilever sensors and;ii) to test the developed diagnostic tools in two specific health care applications, namely:1) the detection of tumour markers in clinical diagnosis and;2) the detection of viruses in pre-clinical diagnosis, providing a verification of the project´s achievements and initiating a generation of innovative products with significant market potential.The proposed project capitalizes on the mechanical properties of micro- and nano-mechanical structures (cantilevers) to measure molecular (ligand-receptor) interactions.Work description:1. Development of a microsensor system based on microcantilevers and surface stress detection, for a general purpose instrument. The microcantilevers will be fabricated using CMOS technology plus post-processing. Signal-processing electronics will be integrated on-chip. The CMOS processing will be subcontracted to a