RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Trading Opulence: New Directions in the Study of Byzantine Luxury Goods for Western Markets (10th - 16th centuries)' (TRAD-ART-BYZ).

assistant: **Innovation**

By focusing on an undervalued field of research, the proposed project will explore, within an interdisciplinary framework, therelationship between the luxury art markets on the two shores of the Mediterranean Sea. A series of high-status artefacts, inscribed inLatin (at times in other languages, too), but produced in the Byzantine East, provides the source material for the project, which willfocus both on the artistic exchanges and on the processes of production and distribution of works of art. The purpose is to studythese processes by simultaneously focusing on the issues of manufacturing methods, patronage, iconography, and epigraphic habits,with a special attention being paid to the choice of scripts and languages on inscribed artefacts. The chronological coverage will spanthe 10th century (the first testimonies to the presence of the Amalfitan community in Constantinople) and 1571 (the conquest ofCyprus by the Ottomans). One of the project’s broader objectives is to move beyond the study of single ethno-linguistic narratives,and to determine the significance of cross-cultural artistic interaction for the development of a Mediterranean economic system andof cultural diffusion and integration in medieval Europe.


**Keywords:** Byzantium, luxury products, exchanges, Mediterranean networks, Maritime Republics, Franks. patronage
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Quantum Simulation of Lattice Gauge Theories - Exploring fundamental physics in the era of quantum information', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Gauge theories are ubiquitous in physics with applications ranging from fundamental high-energy physics(HEP) over emergent condensed matter phenomena to quantum information science and technology. Their study often requires non-perturbative numerical simulations and several regimes of interest remain inaccessible due to the numerical sign problem of Monte-Carlo simulations. Motivated by recent advances in the control of synthetic quantum systems QS-Gauge addresses the quantum simulation of lattice gauge theories (LGTs)beyond the reach of classical computations.Our objectives are (i) to establish a class of regularized gauge theories co-designed for quantum simulation, enabling (ii) the construction of digital quantum algorithms tailored to “LGT-aware” hardware, and (iii) to analyze paradigmatic phenomena such as confinement using classical tensor network (TN) simulations which serve as benchmarks for quantum devices.QS-Gauge is based on an unconventional generalization of the well-established Kogut-Susskind Hamiltonian formulation of LGTs, where the defining non-abelian Lie algebra is deformed to a quantum group. The resulting theories are related to string-net models employed for the classification of topological order in condensed matter which we will leverage to adapt TNs to HEP applications. As these truncated non-abelian LGTs are efficiently represented as multi-level systems, we pursue the development of quantum algorithms for qudits instead of qubits as elementary information carriers. In close collaboration with experimental colleagues and in synergy with the development of early fault-tolerant hardware, we focus on trapped-ion qudit quantum computers and fermionic alkaline-earth Rydberg atoms for optimized (fermion-)qudit architectures. Our results are expected
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Single cell correlates of memory, motivation and individuality' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Directed behavior emerges from neural integration of sensory stimuli, memory of prior experience andinternal states. We seek an understanding of these conserved neural mechanisms using genetically-encodedtools and the relatively small brain of the fruit fly Drosophila. By temporally controlling neural functionmemories can be implanted and internal states altered so that most flies behave according to our direction.Our recent studies have revealed a role for distinct subsets of dopaminergic neurons that innervate a brainregion called the mushroom bodies in reward learning, memory re-evaluation and the control of motivatedbehavior. Although it is recognised that new gene expression is required to form persistent memories, andmolecules are the targets of all therapeutic drugs in medicine, the relevant cellular sites of action oftenremain obscure. Knowing where memories are located in the fly brain therefore makes it possible to gainmolecular level insight, with a unique perspective of being embedded within a relevant cell-specific context,of how a brain operates to alter behavior in response to rewards and internal state. Until recently, moststudies of gene expression in the brain have pooled messenger RNAs purified from the entire brain, dissectedregions, or small populations of fluorescently labeled material. Cell-specific expression and responses aretherefore obscured by averaging signals from, often heterogeneous, collections of cells and cell-types. Wewill use cutting-edge Drop-seq, which permits simultaneous collection of transcriptomes from thousands ofindividually identified cells by first capturing each cell with a unique oligonucleotide-coated bead in ananolitre volume reaction droplet. Our experiments will therefore provide an unprecedented individual celllevelv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Computer Simulation of the Dissolution and Regeneration of Cellulose from Ionic Liquids' (DiReC-IL) targeting Horizon 2020.

assistant: **Abstract**

The technological importance of cellulose, the most abundant and most widely used organic material on Earth is paramount with a very versatile range of applications. It constitutes the basis, among others, for paper and textile industries. Two emerging applications have been gaining importance and substantial attention: one is developing new fiber reinforced nanocomposites. The other novel application is as a carbon-neutral and renewable source for the production of biofuels. Due to its recalcitrance, cellulose fibers always need pre-treatment before actual applications. Traditional techniques work with harmful compounds constituting great environmental risk. In line with the Europe 2020 strategy, cheap and environmentally friendly technologies need to be promoted to achieve a more sustainable and resource efficient economy. Ionic liquids, a novel class of complex solvents with unique properties and a great potential to revolutionize chemical technologies, have been applied as dissolution media for processing cellulose, which has already led to cheaper and “greener” methods. To further develop these technologies, a thorough understanding of the molecular details of the dissolution and recrystallization processes is needed. Although considerable efforts have been dedicated to it, this has not yet been achieved. In this project we propose a new molecular simulation based approach by using enhanced sampling techniques to elucidate the molecular details of the slow and intricate dissolution and recrystallization processes. Unlike previous studies, we will start by investigating glucose and then increase the complexity of the system through larger oligomers enabling us to extrapolate our results eventually to cellulose fibers. This new systematic bottom-up approach will decr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Flexible electrodes based on a zeolitic imidazolate framework and cellulose nanofibers composite: towards wearable energy storage (FLEXSTORE)' (FLEXSTORE).

assistant: **Concept**

The progressive size diminution of electronic modules are undergoing bottlenecks in dwindling charge storage devices i.e., batteries and supercapacitors, constraining their development into wearable energy storage and flexible pollution free technologies. The inherent extended cycle life, rapid charge/discharge, and high power density of supercapacitors rank them superior over other energy storage systems. In modern market of zero-pollution energy devices, recently flexible and lightweight formula are trending to meet the current requirement of wearable energy storage. In this context, cellulose nanofiber (CNFs) incorporated zeolitic imidazole framework (ZIF) as hybridization have the potential to meet this demand, as they are core of active electrode materials for flexible supercapacitors and texturally tailored to demonstrate flexible/foldable properties. Thus, the exploration of the ZIF on CNF as a multifunctional hybrid material will provide high surface area and dispersion stability, while demonstrating  superior analytical performance. FLEXSTOR will elucidate: 1) uniform distribution of ZIF nanocrystals on interface of CNF as conductive electrode 2) the rational design of polymer solid-state gel electrolyte in form of flexible solid-state supercapacitor and 3) the enhanced charge storage performance withstanding the mechanical deformation. With these perspectives, FLEXSTOR will introduce flexible and lightweight active compounds for wearable energy storage devices.


**Keywords:** supercapacitors, flexible solid state supercapacitors, triboelectric nanogenerators, organic-inorganic hybrids, conductive electrodes, wearable energy storage devices
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Lineage tracing of the human brain' (LINMOS) under Horizon Europe.

assistant: **Objectives**

Organisms develop through cell divisions generating clones that progressively organize to form different tissues. This process can be visualized as a cell phylogeny by lineage tracing. In order to track cell lineages, each cell division has to be permanently and uniquely marked. In model systems, this is done by genome editing. In humans this is not applicable, which has historically made impossible to accurately study cell phylogenies. Very recently, however, studies showed that human tissues contain a set of natural markers in the form of somatic DNA variants that permanently and cumulatively label every cell division during development. My work showed that somatic variants are reliable at tracking cell lineages directly in human tissues. Human brain development has historically been difficult to address since human-brain-specific features are hardly recapitulated in any existing model. My project now builds on the use of somatic variants to reveal the cellular processes that form the brain starting from available human material. Somatic variants will be identified at unprecedent sensitivity in a large set of human foetal tissues, including multiple different brain regions. In work package (WP)1, I will identify and study the lineage segregation steps defining the brain phylogeny starting from the zygote. Mathematical modelling will elucidate mechanisms of clone dynamics. In WP2, I will focus on the cerebral cortex and reconstruct cell phylogenies of neural progenitors and the distribution of cortical clones. Furthermore, I will compare normal versus overgrowth cortical malformation brains, where cell proliferation and migration are altered. In WP3, I will develop new strategies to simultaneously assess cell phylogenies and cell-type specification by identifying somat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Genetic and physiological basis of thinness'.

assistant: **Objectives**

The rising prevalence of obesity and associated co-morbidities such as Type 2 diabetes, cardiovascular disease and certain cancers represents a major threat to public health in Europe and worldwide. It can be argued that modern westernized environments are obesity promoting due to unprecedented economic growth, decreased incidence of infectious disease, nearly unlimited food supply, a wide availability of high fat, highly palatable pre-prepared foods, large portion sizes and technological advances leading to a more sedentary lifestyles. The influence on the whole population of environmental factors is undoubtedly powerful, but one remarkable feature of the obesity epidemic is the persistence of enormous individual variation in body weight throughout the population. Individual differences seem to be increasing in both children and adults, with the lean staying lean while the obese become more obese, which indicates that individuals interact differently with the ‘obesogenic’ environment. There is strong evidence that within a population the variance in weight is largely genetically determined. Given that common obesity results from an imbalance between energy intake and expenditure, it is highly likely that this interaction occurs partly through individual variation in appetite and eating behaviours. To date virtually all research based at finding genes related to obesity has focussed on the upper end of the body mass index (BMI) distribution. As part of this proposal I propose a complementary gene finding strategy that focuses on the lowest end of the BMI distribution in order to find genes that confer resistance to obesity in an obesogenic society. The identification of such genes may explain why some individuals do not become obese despite environmental provocation. In
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Large scale bias in the universe' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Research objectives and content A major goal of Cosmology is to determine the density parameter of the Universe, which determines the Universe's future. The best determinations of this parameter come from large-scale structures, where we see evidence that the Universe might be closed, destined to recollapse. Inevitably, this information comes from the distribution of luminous matter, and here lies the difficulty: the density parameter is related to the density of mass, and if the galaxies are not unbiased tracers of the mass, conclusions about the density parameter are changed. Indeed, it is true to say that ignorance of the bias parameter compromises all determinations of the density parameter from large-scale structure studies, and comprises one of the major unsolved problems in Cosmology. We have devised a rigorous method for determining the bias from the statistical distribution of galaxies on large scales. Our aim is to develop this method and apply it to galaxy redshift surveys. Once the bias is known, we will be able to determine directly the future evolution of the Universe Training content (objective, benefit and expected impact) Mathematical skills (Fourier transforms, perturbation theory), Computer skills (FORTRAN 90), Statistical Analysis of large data sets. Links with industry / industrial relevance (22) None
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Structure-function relationship of TAF9 proteins: potential regulators of the survival motor neuron protein complex and targets for rational drug design' in the context of a Sixth Framework call.

assistant: **Objectives**

The main objective of this proposal is the elucidation of the structure and function of TAF9 proteins and of their potential involvement in Spinal Muscular Atrophy (SMA) pathogenesis. Furthermore, the project is expected to provide useful information on th e organization of the eukaryotic nucleus. If a role of TAF9 proteins as molecular targets for SMA emerged from this project, the structure-function relationship will provide the framework for structure-assisted rational drug design for the treatment of SMA and possibly of other neurodegenerative diseases sharing common features. On an international level, the proposed research activity enhances the synergy between European centres of excellence on a research topic of wide interest, by incorporating collaborations with multiple European laboratories as an essential component. In this vein, the project aspires to initiate both future RTN and RTD Marie Curie actions and collaboration with third-country organisations like the FSMA or the MDA (both USA). On a national level, this project will represent one of the most substantial contributions of Greece to the international research effort to find a cure for SMA. The national significance of the project is underlined by the close collaboration the host institute has with academic organisations and large pharmaceutical companies, like AstraZeneca and Pfizer, thus boosting the academic and industrial competitiveness of Greece and the EU in the biotechnology sector. Another key point of this proposal is to facilitate the establishment of the researcher as an independent investigator. This will be achieved through a well-defined project that combines research methodology in the fields of biochemistry and structural biology, in which the researcher collected experience during h
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'CAPFM: a knowledge network portal for cancer and apoptotic functional modules' (CAPFM-PORTAL).

assistant: **Concept**

The main objective of the project described in this proposal is to provide a stable framework for the re-integration of a female European researcher, who has been conducting academic research in top US Institutes for over 5 years. The project will allow th e host institution to benefit from the knowledge and experience acquired by the applicant in her previous training and work in Europe and the USA. The applicant's strong background in molecular biology and bioinformatics are of significant importance to th is proposal. As a result of this action, the applicant will continue her professional activity in her field of expertise in the EU by developing a network portal related to cancer and apoptosis. The scientific objective of the CAPFM portal network is to identify novel functional modules involved in cancer and apoptosis. This network will use informatic tools and input from experimentalists. Experimental validation of significant prediction subsets will be an integral part of the process, leading to a con tinuous iterative improvement in the methods. The network portal will bring together the results obtained from many of the best European laboratories, to create a European concerted network focused specifically on cancer and apoptosis. The development of t his portal will encourage and optimize cooperation rather than duplication of effort, and will also be pro-active, encouraging closer integration between the experimentalist and bioinformatician. The information contained in the CAPFM will be available in the public domain and easily accessible through a single interface in the web, using a distributed annotation system (DAS) to ensure interoperability, which will evolve to take advantage of new developments in the GRID.Combating cancer is one of the seven main ob