RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'School-to-Work Transition of Youth with Vocational Qualifications. Cases of Germany and Italy' (TWISTY) under Horizon Europe.

assistant: **Objectives**

The transition from school to the labour market is a significant milestone in every person's life, marking the path to adulthood, career, and independence. However, this transition may pose challenges for youth, leading them to unemployment. Such experiences not only create economic imbalances in labour markets and increase social tension but also have long-lasting effects on individual well-being. Despite ongoing EU and global efforts, such as the 2020 Recommendation on Bridge to Jobs and SDGs 4 and 8, many young people face difficulties in securing stable employment, especially endangered is youth with vocational qualifications. Existing policies, addressing economic indicators of labour markets, often leave unaddressed real experiences of youth and how national systems of school-to-work transition (STWT) shape these experiences.The project “School-to-Work Transition of Youth with Vocational Qualifications: Cases of Germany and Italy” (TWISTY) addresses these gaps by focusing on biographies of young people navigating or finishing their transitions to stable employment. The project’s novelty lies in contrasting these experiences with policy narratives, identifying mismatches and disclosing overlooked factors in current practices. It focuses on Germany and Italy because despite political, social and economic similarities, they demonstrate astonishing differences in youth unemployment and organisation of STWT systems. Through the policy analysis and study of individual experiences, TWISTY will offer bottom-up solutions to improve STWT strategies. The findings will not only fill in the gaps in understanding of personal trajectories of skilled youth to stable employment in complicated STWT systems but also inform more nuanced policy recommendations that can be adapted to o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Floer homology, symplectic automorphism groups and algebraic k-theory' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Recently strong links between mathematical physics, symplectic geometry and algebraic geometry have been established through the discovery of 'quantum cohomology'. The proposed project would be to study connections between the topology of symplectic automorphism groups and the algebraic structure of the quantum cohomology ring. This includes the development of algebro-geometric methods to make computations in Floer homology. A second part would treat analogues of the classical K-theoretical surgery obstructions (leading for example to a 'Floer simple homotopy type'). The methods to be used come from nonlinear analysis, topology and algebraic geometry. Research would be supervised by Prof. Donaldson, leading to a D. Phil thesis.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Mechanisms of bone marrow sequestration during malaria infection' (BoneMalar) targeting Horizon 2020.

assistant: **Abstract**

Malaria remains a major problem of public health in developing countries. It is responsible for about 600000 deaths per year, predominantly children in sub-Saharan Africa. There is an urgent need for novel therapies as resistance against current treatments is widespread. The complex parasite biology requires a multifaceted approach targeting multiple life cycle stages and virulence pathways. The pathogenesis of the most deadly of human malaria parasites, Plasmodium falciparum, is related to the capability of infected red blood cells to sequester in deep tissues. Sequestration is critical for the completion of the red blood cell cycle because the release of parasites into the blood circulation allows recognition by surveillance macrophages and clearance in the spleen. A series of studies have since led to the understanding that sequestration of asexually replicating parasites is caused by the adherence of parasite infected red blood cells to the vascular endothelium of various tissues in the body. We have recently demonstrated that gametocytes, the only stage capable of transmission to the mosquito vector, develop in the extravascular environment of the human bone marrow. Preliminary studies in the mouse model have confirmed this finding and also suggest existence of an asexual reservoir in the bone marrow. In this innovative multidiscipinary proposal we aim to investigate the host pathogen interactions at the interface between infected red blood cell and bone marrow vasculature. Specifically we will focus on the following questions: how do parasites home to bone marrow? What are the changes in the bone marrow endothelium upon infection? How do parasites adhere with and transmigrate across the vascular endothelium in the bone marrow? The proposed studies initiate detaile
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Novel Applications in 19F Magnetic Resonance Imaging' (NOVA-MRI), addressing dissemination and exploitation.

assistant: **Impact**

Magnetic resonance imaging (MRI) is a leading clinical diagnostic technique that is able to provide whole body imaging, and when individual cells are imaged in living animals, it can provide new insights into the biology of cell trafficking and migration. For cells to be visualised by MRI, they generally must be labelled to enable their discrimination from surrounding tissue. The development of magnetic resonance imaging (MRI) contrast agents is therefore an active area of research, where the basis for this interest is the expansion of MRI as a high-resolution and non-invasive important preclinical and clinical imaging modality. Moreover, there are now new opportunities to developing smart materials with multifunctional abilities including MRI contrast in-built within biomaterial structures, functionalisation with targeting ligands and the carrying of a therapeutic payload. This move towards a new generation of MRI contrast reagents has also been spurred on by the mounting evidence against gadolinium-based contrast agents (GBCAs). They are currently the agents of choice and were considered historically safe and well tolerated until recently. However, they have been found to accumulate in various tissues of patients who do not have renal impairment, including bone, brain and kidneys. Furthermore, in 2015, the FDA released a new safety announcement regarding GBCAs and the risk of accumulated deposits in the brain following repeated use. Whilst GBCAs are being investigated, they can still be administered but healthcare professionals have been advised to limit the use of GBCA to situations in which contrast is deemed absolutely necessary.This has opened the door to the novelty of using perfluorocarbon (19F) being incorporated inside smart nanoparticles, which can offer uniq
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Senescence and sexual conflict in a model insect species (Tribolium castaneum): a test of evolutionary ideas' (AgeingSexualConflict), addressing dissemination and exploitation.

assistant: **Impact**

The fundamental question 'why do organisms age?' remains among the most enduring challenges in evolutionary biology. One of the most complex aspects of ageing is sex-specific selection on ageing rates and, more generally, the dynamic link between ageing and sexual conflict. Although sexual conflict was recognized over 30 years ago, its role in adaptive evolution has only recently received theoretical and empirical attention. Sexual conflict is currently recognized as a key evolutionary process, and recent evidence suggests that it can drastically influence patterns of ageing by acting as both a catalyst of and a constraint to the evolution of sex-specific life histories. Considerations of sexual conflict are therefore fundamental to understand why males and females age at different rates, the costs of sex and, ultimately, the evolution of ageing. Unfortunately, ageing theory has largely neglected sexual conflict, while theory of sexual conflict has only begun to consider ageing. The integration of these topical areas of evolutionary biology is in its infancy and, as a consequence, comprehensive work investigating the relationship between sex-specific patterns of ageing and –simultaneously- interlocus sexual conflict (IRSC) and intralocus sexual conflict (IASC; the two fundamental mechanisms of sexual conflict) has been extremely rare. Using a model insect species (Tribolium castaneum), I propose a strongly experimental approach aimed to address some of the fundamental evolutionary questions concerning ageing and sexual conflict: a) Does the intensity of interlocus conflict (IRSC) influence ageing rates and, does senescence foster IRSC?, b) Does intralocus conflict (IASC) constrain the evolution of sex-specific ageing rates?, and c) How do IRSC and IASC interact to influ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'H.C. Ørsted Fellows Programme – co-funded by Marie Skłodowska Curie Actions (COFUNDfellowsDTU)' (COFUNDfellowsDTU) targeting Horizon 2020.

assistant: **Abstract**

With the H.C. Ørsted Fellows Programme – co-funded by Marie Skłodowska Curie Actions (COFUNDfellowsDTU) DTU will attract highly talented young researchers through incoming mobility from around the world. The Programme takes place at the Technical University of Denmark (DTU) which is a top ranked university with focus on all Engineering Sciences as well as Life Science and Biotechnology.The Programme will provide uninterrupted continuity of the existing and highly successful co-funded Programme and introduce new improvements by offering both junior and senior fellowships, increase the number of fellowship years to 126, introduce effective career development and increase focus on industrial secondment and exploitation of innovative research results.Fellows will have the opportunity to shape their careers within the world-leading innovative environment at DTU, by engaging in curiosity-driven, bottom-up research according to their own choice within all available branches of engineering science. The Programme will introduce the opportunity of a 3 months secondment in industry, and implement the triple I – international, interdisciplinary and intersectoral exposure. This will prime fellows for careers in both academia and industry, and put innovation at the centre of the Programme. Grants will be awarded in open, international competition. The selection of successful proposals will be carried out in a process comprising the following three steps: 1) International peer review of each application by three reviewers, 2) Rebuttal to peer review from applicants and 3) Final decision on the award of fellowships by the DTU Selection Committee.DTU will ensure equal opportunity and introduce anonymisation of applicants' names and gender during the review process. The Programme is open
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'A multidisciplinary approach to the reduction in lameness and improvement in dairy cow welfare in the European Union' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

Lameness in dairy cows is a major economic and welfare problem. Interaction between husbandry systems, development of lameness and its biological causes are poorly understood. The project aim is to reduce lameness by identification and application of best practice and an understanding of underlying biological mechanisms. This will contribute to improved welfare, productivity and competitiveness in the EU dairy sector. A multidisciplinary approach using expertise in hoof trimming, housing/husbandry systems, fundamental biological research and quantitative statistic/ will provide an understanding of causes of lameness and will form the basis for sustainable prevention of lameness. Outputs: guidelines for minimal - lameness husbandry systems and training packages for the dairy sector. Socio- economic outcomes: reduced incidence of lameness, improved animal health and welfare, husbandry systems and product quality and increased productivity.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Linking within-host and between-host evolution of multidrug-resistant Mycobacterium tuberculosis' (ECOEVODRTB) under Horizon 2020.

assistant: **Objectives**

Mycobacterium tuberculosis (Mtb), the etiologic agent of tuberculosis (TB), is the main cause of human deaths due to infection in general, and to antimicrobial resistance in particular. Little is known on the within-host evolution of Mtb. Theory predicts that in chronic infections like TB, short-sighted evolution operates in the light of a trade-off between virulence and transmission. This trade-off is particularly relevant in the context of drug resistance, given the fitness costs of resistance. However, the role of short-sighted evolution in TB has never been explored empirically. Theory and model systems further predict that phenotypic drug tolerance facilitates the emergence of drug resistance, but the relevance of phenotypic drug tolerance for drug resistance evolution in the clinic has not been established for TB or any other bacterial disease. To address these and related questions, I propose to build on my recent work on the transmission of drug-resistant Mtb with a new focus on the within-patient evolution of drug-resistant Mtb and its link to between-patient evolution during transmission.Specifically, I shall:1) Define the genomic characteristics and evolutionary forces shaping multidrug-resistant Mtb populations in individual patients over time and across different body compartments;2) Compare the genomic and phenotypic properties of multidrug-resistant Mtb populations in individual patients to those circulating within the corresponding patient population;3) Determine the effect of suboptimal patient treatment and phenotypic drug tolerance on drug resistance evolution in Mtb inside patients.By combining population genomics of Mtb sampled sequentially and from surgical specimens with experimental evolution and phenotypic characterization of clinical and experi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Comparative analysis on nuclear fragmentation' (1994-1998).

assistant: **Innovation**

The present project can be regarded as an attempt to establish the link between different theories for multifragmentation processes, namely percolation theory that has been proposed by several authors as a possible explanation for nuclear fragmentation, lattice gas theory and classical molecular dynamics. The main objectives of the project can be summarized in the following points:  i) To find an explanation to the existence of the scaling property in t size distribution of the fragments within the framework of molecular dynamics, a property that is well established both in percolation and lattice gas theories. ii) To establish a mapping between the thermodynamic phase diagram and the percolation diagram by characterizing the different regions and critical points. iii) To analyse the geometry and size distribution of the fragments as a func- tion of the range of the interaction. The Coulomb long-range interaction will be considered as a special and very interesting case.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Hydrodynamic characterization of biofilm airlift suspension reactor' to be submitted under Fourth Framework.

assistant: **Abstract**

The BAS technology is a compact high rate nitrification system for industrial wastewater. This technology is already successful applied. In this project we will work on the extension of this reactor for denitrification. A newly designed reactor will be studied on its hydrodynamic characteristics on pilot scale. Based on this characterization a mathematical model for the scale-up and optimization of the process will be formulated. This reseacrh will also contribute to a further understanding of three phase reactor systems.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Diagnostic tool for Vaginitis'.

assistant: **Concept**

Vaginitis is a frequently occurring medical disorder in women associated with substantial morbidity and formerlyundetected complications. It is one of the most common problems in clinical medicine, and it is the reason citedmost often for visits to obstetricians and gynaecologists. Today, there is no point-of-care diagnostic tool that candiagnose all six possible causes to vaginitis correctly, rapidly and in a comprehensive manner. It is estimated tobe misdiagnosed in around 50% of first non-expert physicians' clinic visits and about 30% of women with vaginalcomplaints remain undiagnosed despite extensive testing. GynTools has developed a unique (patent pending)vaginal discharge collection tool, composed by two products: (1) VagX I™ a rapid point of care diagnostic devicefor Gynaecology clinics and (2) VagX II™, a Vaginitis self-test kit for home use.VagX is the first diagnostic system that can diagnose all six Vaginitis conditions; does not require special skills ortraining and it is faster and cheaper from any current alternative. VagX system provides a comprehensive point ofcare vaginitis diagnostic tool for gynaecologists and primary caregivers that are not experts in vulvovaginaldisorders. Leveraging AI and Deep Machine Learning, VagX allows any caregiver to correctly diagnose all sixvaginitis conditions, within minutes. GynTools seeks funding to conduct a feasibility study to prove technical andcommercial viability, conducting an analytical exercise to position the product. The objective is to test theeconomic viability of the device among a larger pool of potential clients (user-acceptance), and to assess if thechosen commercialisation approach will be conducive of the projected growth on the European level.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Galileo Advanced features for Maritime domain: Breakthrough Applications for Safety and Security' (GAMBAS).

assistant: **Concept**

Galileo-based solutions for a better surveilled, safer and more secure seaMaritime transportation is a backbone of the worldwide economic growth, representing 80% of the worldwide merchant traffic, and a major domain of human and nature activity.The improvement of maritime safety and security has always been a major concern for the global community, and, in the last decades, the protection of environment and the resilience to climate change effects have also appeared in the overall scope.Considering the size of the maritime domain and the potentially large distances to coasts, the GNSS is a core technology of maritime systems. Getting the best possible information from on-board GNSS receivers and more generally GNSS applications (including Search-and-Rescue payloads and short-messaging capabilities of GNSS satellites) is then beneficial to the maritime community for a minimum additional investment.Galileo system is bringing new assets and functionalities, in particular compared to other GNSS constellations, which appears to be particularly relevant for the maritime community.The objective of the GAMBAS project is to highlight how Galileo specific features can benefit to maritime domain, to propose implementations and to support demonstrations and disseminations of associated services, for the benefit of maritime domain in terms of security, safety, protection of environment and resilience to major catastrophic events.The project will in particular address the modernization of SSAS Cospas-Sarsat anti-piracy beacon, with unique Galileo return-link features, and the development of solutions for rescue operators and for the vessels to use Galileo robustness to jamming and spoofing (including authentication) and the expected future Emergency Warning Service. The solution wil