RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'A distributed TELEmatics environment for treatment PLANning in stereotactic radiosurgery'.

assistant: **Objectives**

Accelerator-based Radio surgery has been proven as a non-invasive, safe and cost-efficient treatment possibility with a wider range of applications and a lower complication and better survival rate then conventional surgical or Radiation techniques. However, specially trained staff is required to handle treatment planning and treatment procedures within these installations. While the treatment hardware and immobilization devices (frames) need to be available locally (at the treatment site), the treatment-planning set-up (equipment and staff) may be provided by a remote establishment using advanced telematics infrastructure. The objective of the project is to design and develop a Distributed Telematics environment for outsourcing the complete dosimetric treatment-planning procedures.Objectives:The aim of this project is to address the clear need for cost-effective and continuous provision of Healthcare services in the area of Accelerator-based Radio surgery, a non-invasive, safe and cost-efficient treatment possibility with a wider range of applications and a lower complication and better survival rate then conventional surgical or Radiation techniques. Specially trained staff is required to handle treatment planning and treatment procedures within these installations. While the treatment hardware and immobilization devices (frames) need to be available locally (at the treatment site), the treatment-planning set-up (equipment and staff) may be provided by a remote establishment using advanced telematics infrastructure. The objective of the proposed project is to design and develop a Distributed Telematics Environment for outsourcing the complete dosimetric treatment-planning using modern telematics tecnologies.Work description:The proposed system will be built upon moder
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Chemical Manufacturing Methods for the 21st Century Pharmaceutical Industries' (CHEM21) targeting Seventh Framework.

assistant: **Abstract**

CHEM21 is a project that will develop a broad based portfolio of sustainable technologies for green chemical intermediate manufacture aimed at the pharmaceutical industry. Initially working with the EFPIA members the collaborators of CHEM21 will analyse a number of projects that are in development to decide which the priorities are for technology development. This analysis will also be used to update the literature of green technology based on updating previous papers.The technology being developed is divided into three work packages based on chemical catalysis and synthetic methods, biocatalysis and synthetic biology. The first effort will investigate the use of a range of catalysts with a main focus on replacing and applying catalysts based on common metals rather than the precious metal based catalysts that have limitations of sustainable supply. Use of continuous reactors and process intensification will also be addressed as well as fluorination chemistry. In biocatalysis a range of projects based on the needs identified by the chemical round table have been chosen including amide synthesis, stereo- and regio-specific hydroxylation of complex molecules as well as other redox reactions. Again process engineering and supercritical solvents will be developed as intensification methods. In the third part the development of the emerging field of synthetic biology will be addressed with the development of enzymatic chemical cascade pathways in fermentation strains with freedom to operate to produce targets of interest.Finally the outcomes of the efforts described will be incorporated into education and training efforts to produce the next generation of process chemists with a good understanding of green and sustainable metrics.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Surface-COnfined fast-modulated Plasma for process and Energy intensification in small molecules conversion', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The SCOPE project will introduce a ground-breaking approach to use renewable energy in three major industrial reactions: 1) N2 fixation, 2) CH4 valorization and 3) CO2 conversion to liquid solar fuels. We will use non-thermal plasma, which has large potential to convert these small (low reactive) molecules under near ambient temperature and pressure, particularly for distributed processes based on renewable energy. The new processes have drastically lower carbon footprint (up to over 90% with respect to current ones). Furthermore, CO2 conversion is crucial for a world-based distribution of renewable energy. However, the selectivity and energy efficiency of plasma technologies for these reactions are too low, making radically new approaches necessary. The Project idea is to realize a highly innovative approach for non-thermal plasma symbiosis with catalysis. By inducing excited states in solid catalysts to work in synergy with the excited short-lived plasma species, we introduce a brand new idea for catalyst-plasma symbiosis. In addition, we introduce a fully new concept of nano-/micro-plasma array through a novel electrode design, to generate the plasma at the catalyst surface, thereby overcoming long distance transport. By embedding ferro-magnetic nano-domains in the catalyst support and inducing radiofrequency heating, we create fast temperature modulations directly at the catalyst active sites. Combining these elements, the project will overcome the actual limits and enhance the selectivity and energy efficiency to levels suitable for exploitation. This requires a synergy over different scale elements: nano at catalyst, micro at the level of modelling plasma generated species, milli at the reactor scale and mega at the plant level for sustainability-driven opportunit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Cross-border strategic collaboration by European MNCs: a multi-level investigation of the effects of individuals, organizations and societies' (COLEUMNC).

assistant: **Concept**

Cross-border collaboration is essential for the EU to reach its vision of becoming the most competitive and dynamic economy in the world, based on knowledge, capable of sustainable economic development with more and better jobs and a stronger social cohesion". According to UNCTAD, managers of top MNCs reported that 30% of their future foreign direct investments would be made through collaborative strategies. Of the world's top 100 MNCs, 59 are European, which puts a premium on studies of cross-border collaboration in a European context.The aim of the project is to investigate the impact of individuals, organizations and societies within the EU on cross-border strategic collaboration. Most existing research on cross-border strategic collaboration is conducted in the US and Canada, often with a heavy bias toward North American interests. This research project aims at establishing a European centre of excellence in cross-border collaboration by building on the Strategic Alliance Research Network (SARN), recently established by the applicant, in order to foster international research collaborations. Dr Bernhard Bo Nielsen proposes to return to Denmark and coordinate a research project at University of Southern Denmark (SDU), utilizing the knowledge, experiences and contacts he has gained in the US over the past seven years.The objective is to conduct cutting-edge, relevant research within the European context ,while working in close cooperation with colleagues in North America and the world at large."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Cm-wave continuum emission from molecular clouds' (CMWAVECLOUDS).

assistant: **Concept**

The anomalous foreground was detected 10 years ago as an unexpected Galactic screen at cm-wavelengths in experiments designed to map the Cosmic Microwave Background (CMB), seen in the direction of cirrus interstellar dust clouds and ubiquitous at high Galactic latitudes. A joint Universidad de Chile (U. Ch.) and Caltech effort led to the discovery of surprisingly bright radio emission from canonical dark (i.e. dusty) clouds: rho Oph and M78, as well as translucent LDN1780 and zeta Oph. What is the nature of the cm-wave emitters? Do the dark clouds and the cirrus clouds radiate by the same emission mechanisms? The identification of the cm-wave sources is required to inform the subtraction of diffuse Galactic foregrounds from CMB polarization experiments. It may also provide a new diagnostic of the interstellar medium (ISM). The data on well studied local clouds can bring information on the environments giving rise to cm-wave radiation. The U. Ch. participant seeks to collaborate with the ISM team at the LUTh laboratory of the Observatoire de Paris, who has an established expertise on the theoretical modelling of ISM physical conditions. We aim at distinguishing between two broad interpretations of the cm-wave emission, based either on unexpected physical conditions, or a new astrophysical process: 1- Cold plasma radiation due to residual charges in molecular gas, such as CI continuum from the external layers (the photo-dissociation-regions) of clouds exposed to interstellar soft-UV radiation. If confirmed the CI continuum would trace unexpectedly dense and clumpy molecular gas in regions of intermediate-mass star formation. 2-The exciting possibility of spinning dust emission, which may provide the first direct probe of interstellar very small grains (such as polycyclic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Simultaneous Detection of Multiple DNA and Protein Targets on Paramagnetic Beads Packed in Microfluidic Channels using Quantum Dots as Tracers' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The detection of DNA hybridization and protein recoginittion event (immunoassay) is very important for the diagnosis and treatment of genetic diseases, for the detection infectious agents and for reliable forensic analysis. Recent activity has focused on the development of hybridization assays that permit simultaneous determination of multiple DNA or protein targets, using optical or electrochemical coding technology, based on unique encoding properties of semiconductor crystal nanoparticle tags (quantum dots). Described multi-target bio assays were performed in batch mode, involving significant amount of steps, connected with the possibility of human error, time and reagents consuming. Lab-on-a-chip technology offers tremendous potential for obtaining desired analytical information in a simpler, faster and cheaper way compared to traditional batch/laboratory-based technology. Particularly attractive for multiple DNA and protein recognition applications (i.e. point-of-care) is the high-throughput, automation, versatility, portability, reagent/sample economy and high-performance of such micromachined devices. Overall objective of the proposed research is to create and characterize a portable microanalyzer, based on a novel advanced Lab-on-a-Chip technology with magnetic separation and end-column quantum dots tracers voltammetric detection of multiple DNA and protein targets for point-of-care , automated, high-throughput, sensitive, selective and simultaneous assays. The new micro-total analytical system will rely on coupling of microfluidic transport of samples, effective flow-through magnetic separation complementary/non-complementary DNA and protein targets and a novel chip-based voltammetric stripping detection of quantum dot tags. To successfully complete such advanc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Brain mechanisms of human limb movement sense' under Seventh Framework.

assistant: **Concept**

Proprioception involves the sense of limb position and movement of body parts. It is critical for motor control, as without knowing where your body parts are it is impossible to move them accurately. Proprioception relies on the integration of various inputs, from muscle spindle receptors, Golgi tendon organs, skin stretch receptors, visual, auditory and vestibular inputs, and signals of motor command. How and where these signals are integrated in the human brain is still unclear.Here we will use state-of-the-art brain imaging and brain stimulation methods in combination with perceptual illusions to identify neuronal populations that are involved in the integration of multisensory and efferent motor command signals for proprioception. Our hypothesis is that the primary motor cortex is involved in this process by storing a common neuronal representation of motor commands and movement sensations. Furthermore, the posterior parietal cortex is hypothesised to play an essential role in the integration of multisensory signals to optimise the sense of limb position.To test these predictions we will use limb-movement illusions induced by different combinations of efferent or afferent signals. In the efferent-induced illusory condition, subjects perceive movement when they try to move a limb, while this movement is prevented by either an ischemic or a physical block. In the afferent-induced condition, subjects perceive movement when their muscle stretch receptors are stimulated with tendon vibration. The role of visual signals will be studied by providing visual feedback of moving limbs with virtual reality technology. To identify groups of neurons with specific properties, we will use fMRI-adaption methods that extend the spatial limitation of traditional fMRI. After having ide
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'POLicy for NAtural RESouces' (POLINARES), addressing dissemination and exploitation.

assistant: **Impact**

POLINARES concentrates on the global challenges faced with respect to access to oil, gas and mineral resources over the next 20 years and proposes solutions for the various policy actors, including the EU. Combined theoretical and empirical analyses will use expertise from a wide range of disciplines including political science, economics, geology, engineering, technology, law and security studies. The initial aim will be to understand the causes of past and current conflict and tension relating to access to these resources and identify emergent sources of future conflict and tension. New frameworks for analysis will be developed using historical experience and political and economic theories. Future availability and demands for energy and other selected minerals will be assessed to provide the basis for evaluation of potential future sources of tension and conflict. Technical and economic data for critical resources will be analysed for key factors determining recent and future supply and demand, and to develop scenarios for the future. Current and recent practices and strategies of key actors will be examined to understand, refine and calibrate theoretical models developed. Building on scenarios developed to identify and assess the major future risks for tension and conflict, POLINARES will integrate assessments of future supply and demand with the understanding of the behaviour of actors and their interactions and interdependencies. Later, the project is devoted to identifying future policy approaches. POLINARES will establish a new set of criteria for evaluating past, current and future policy approaches, and will develop new understanding from how experience in other natural resource sectors of different approaches have been and can be used. A novel set of policy a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Reduction of Suicides and Trespasses on RAILway property' (RESTRAIL).

assistant: **Concept**

The aim of the RESTRAIL project is to reduce the occurrence of suicides and trespasses on railway property and the costly service disruption these events cause, by providing the rail industry with an analysis and identification of cost-effective prevention and mitigation measures.The project starts by identifying the state of the art of best practices and research findings (inside and outside Europe) combined with an analysis of factors (internal to railways or external such as  media communication) influencing the occurrence of suicides and trespasses and their consequences, based on official data sources and other collected data. This work will consider hotspots and other high risk access points such as level crossings, station platform ends and bridges.This is followed by an assessment of existing countermeasures (technical and soft) for reducing suicides, preventing trespasses and mitigating the consequences on rail operations. Attention will then be given to the development of new approaches particularly those involving soft measures. The project will demonstrate some selected measures in order to evaluate the findings and finally develop recommendations and guidelines.This project is led by railways since it is a rail related topic which aims to answer the concerns of the rail industry. However an essential feature of the project is the involvement of a wide range of relevant professional expert knowledge in the areas of human science and health, law enforcement, emergency services, education and social services, media and communication, road and rail. This will ensure the project output is of practical use to all who can be involved with suicides and trespasses.The final outcome will be a toolkit, accessible through a user friendly interface (for consultation and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The Crosstalk Between Red And White Blood Cells: The Case Of Fish' (BLOODCELLSCROSSTALK) targeting Horizon 2020.

assistant: **Abstract**

Fish are the phylogenetically oldest vertebrate group with an immune system with clear similarities to the immune system of mammals. However, it is an actual matter of fact that the current knowledge of the fish immune system seems to lack the key piece to complete the puzzle. In 1953 Nelson described a new role of human red blood cells (RBCs) which would go beyond the simple transport of O2 to the tissues. This new role, involved in the defence against microbes, described the antibody and complement-dependent binding of microbial immune complexes to RBCs. Regardless of the importance of this finding in the field of microbial infection, this phenomenon has been poorly evaluated. Just recently, a set of biological processes relevant to immunity have been described in the RBCs of a diverse group of organisms, which include: pathogen recognition, pathogen binding and clearance and cytokines production. Furthermore, it has been demonstrated that nucleated erythrocytes from fish and avian species develop specific responses to different pathogen associated molecular patterns and produce soluble factors that modulate leukocyte activity. In the light of these pieces of evidences, and in an attempt to improve the knowledge of the immune mechanism(s) responsible for fish protection against viral infections, we raised the question: could nucleated fish erythrocytes be the key mediators of the antiviral responses? To answer this question we decided to focus our project on the evaluation of the crosstalk between red and white blood cells in the scenario of fish viral infections and prophylaxis. For that a working model composed of the rainbow trout and the viral haemorrhagic septicaemia virus (VHSV) was chosen, being the objectives of the project to evaluate: i) the implication trou