RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Photooxidation of 3h-pyrroles and 2-azabutadienes singlet oxygen - 4+2 - cycloaddition to 2-azadienes' (1994-1998) under Fourth Framework.

assistant: **Objectives**

There is a great interest in the study of photooxidations with singlet oxygen due to the important role which play in oxidative damage to DNA and its biological consecuences in living cells. Several products of the photooxidations of nucleic acid derivatives have been reported and intermediates such as endoperoxides have been proposed to account for them. This endoperoxides are the products of singlet oxygen (4+2) cycloadditions. The (4+2) cycloaddition reaction of singlet oxygen to 1,3-dienes has been extensively studied from both synthetic and mechanisthic points of view and this is a important field of research at Professor Adam's group. However, there is a few examples of singlet oxygen photooxidations of azadienes in spite of the fact that (4+2) cycloadditions of singlet oxygen to a 2-azadiene moiety present in the molecule is suspected to be the first step in the most of the photooxidations proccess of the nitrogenated bases in DNA or of imidazole residues present in the polypeptide chain of several enzymes like insuline and ribonucleasa. The objetive of the research work will be: (a) The study of the (4+2) cycloadditions of singlet oxygen to 2-azadienes. (b) The use of the obtained products in Synthetic Chemistry. (c) The study of the 3,14-facial selectivity of this kind of cycloadditions with different 3,14-faces Two kinds of 2-azadienes are proposed for its photooxidations: 1. 3,3-disubstituted-3H-pyrroles 2-azabutadienes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Flexible Hybrid Sodium Ion Capacitors from Renewable Electrospun Lignin: Device Manufacture, Performance Testing and Solid Electrolyte Layer Investigations'.

assistant: **Objectives**

This project aims to develop a sustainable, environmentally friendly, flexible, Hybrid Sodium Ion Capacitor to support the rapid development of flexible/wearable electronics and sodium ion energy storage technology. This will be achieved by integrating a flexible hard carbon battery-style anode (higher energy density) and a flexible porous carbon supercapacitor style cathode (higher power density), electrospun from renewable lignin, into one energy storage device. As a result, this device will deliver higher energy density than flexible supercapacitors, while maintaining high cyclability and power density.These electrodes will be produced under the guidence of Prof. Titirici, a world-renowned expert in sustainable carbon materials/energy storage.The choice of sodium in this project over lithium is for the following reasons: (i) Na is more abundant and more evenly globally distributed on land (salt, sodium carbonate, and sodium hydroxide) and in salt water, (ii) Al current collectors can be used, instead of Cu in Li, representing a considerable cost saving, and (iii) metal plating of the carbon electrodes occurs less in Na, suggesting that cyclability will be greater with Na than Li.Finally, the fundamentals (solid interface layer, cathodic interlayer) in using Na ions for hybrid capacitors will be examined extensively using laboratory based techniques (XPS and SEM) and synchrotron methods (NEXAFS/XANES). Understanding the formation of this layer is vital to producing flexible hybrid ion capacitors, as it's formation is one of the leading causes of reduced Coulombic efficiency in batteries resulting in premature failure and poor capacity retention.


**Keywords:** Hybrid Ion Capacitors, Solid Electrolyte Interface, NEXAFS
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Functional Adaptive nano-Materials and technologies for energy efficient BUILDings' (FOAM-BUILD), addressing dissemination and exploitation.

assistant: **Impact**

FoAM-BUILD will develop next generation External Thermal Insulation Composite Systems (ETICS) for new builds and retrofitting applications. This comprises innovations in:1) Insulation material: development of new, lightweight and highly insulating nano-cellular foams, with a 50% reduction in thermal conductivity compared to conventional insulation elements. Non-halogenated nano-based flame retardants will be developed and incorporated into these materials using new processing routes.2) Active monitoring and control of moisture: a control system will be developed based on a sensor network to measure moisture and liquid water. Data from the sensors will be combined with an intelligent system for moisture prediction, and the system will respond by activating a ventilator system incorporated into the building’s heating, ventilation and air conditioning (HVAC) system to dry targeted areas of the façade.The materials and systems will be tested and demonstrated within the project by industrial end-users, with the creation of a demonstrator insulation material, sensor network and intelligent system, ventilation system and a full-scale façade system at TRL level 6. By deployment of FoAM-BUILD technology energy savings of 192,000 kWh to 288,000 kW will be achieved over a façade lifetime of 30 years. Additionally the new biofilm protection system will extend the service life of the façade surface from 5 years to 20 years for a north façade in central Europe.FoAM-BUILD is characterised by an exceptionally strong industrial participation (6 of 10 partners, including market-leader DAW), which will ensure the high commercial relevance of developments. Close attention has been paid to IPR management, and tailored standardisation, dissemination, exploitation and training activities will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Targeting cancer using evolutionary refined pathogen derived antigens' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

We have recently discovered a malaria protein which has shown a high potential in cancer treatment. In pregnant women, malaria infected red blood cells express a protein that binds to a distinct carbohydrate structure present only on cells of the maternal side of the placental circulation, but not elsewhere in the vasculature. This highly evolved binding system enables the parasite to evade clearance and infect placental tissue, causing pregnancy-associated malaria. This malaria protein binds to most cancer cells with a highly specific and strong interaction. It is apparent that cancer cells commonly express this modified glycoprotein, also found on placental cells, but rarely on normal somatic cells. The carbohydrate structures enable cancer cells to migrate and invade surrounding normal tissue, and to play a role in metastatic spread of the primary lesion.I have preliminary data showing that (1) the malaria protein binds specifically to a wide range of cancer cells and patient cancer tissues including melanoma, lymphoma, carcinomas and sarcomas, whereas no binding is detected to normal healthy cells or tissue, and (2) cancer cells treated with the malaria protein have markedly reduced growth and migration capacity.This raises the intriguing possibility that we can use this naturally refined parasite-host interaction mechanism as a tool to specifically target cancer and inhibit the metastatic potential. Furthermore, as the malaria protein binds strongly to patient-derived cancer tissues, the malaria protein could be used to differentiate between specific subtypes of cancers and possibly advance the diagnostic process in clinical settings. The proposed project augments a novel strategy of targeting a wide range of receptors involved in human disease using pathogen deriv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Development, enhancement and complementation of animal-sparing, foot-and-mouth disease vaccine-based control strategies for free and endemic regions' (FMD-DISCONVAC) targeting Seventh Framework.

assistant: **Abstract**

Foot-and-mouth disease (FMD) is one of the world’s most infectious diseases of livestock and continues to pose a significant threat to endemic and free regions alike. The impact of FMD on society and international trade is high, thereby demanding stringent prevention, surveillance and control plans taken up in crisis preparedness plans. On the other hand, there is a global increased demand for animal welfare and ethical considerations necessitating a decreased reliance on eradication of animals to control FMD virus (FMDV) spread, and on the use of animals for the regulatory testing of veterinary products. The project seeks to balance these apparently contracting viewpoints by addressing specific gaps in our knowledge on all aspects of FMD control to enable implementation of enhanced animal-sparing vaccine-based control strategies tailored to the needs of free and endemic settings. Consequently, four main objectives have been identified, including (i) the improvement of the quality of existing FMD vaccines and diagnostics, (ii) the refinement and replacement of in vivo FMD vaccine quality tests, (iii) the development of new generation FMD vaccines and diagnostics by applying cutting edge technologies, and (iv) the enhancement of our knowledge on FMDV spread and transmission following the use of high-potency monovalent or multivalent vaccines. The role of wildlife (buffalo, gazelles and wild boar) in FMDV maintenance and transmission will also be investigated. The project consists of seven different, yet interlinked, work packages (WP) each addressing one of the items listed in the Work Programme topic KBBE-2008-1-3-02, and led by renowned WP leaders with years of relevant experience in the field of FMD. As such, significant progress towards the objectives of the Communit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Engineering neural stem cells and ensheathing glia for nigrostriatal regeneration.', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

We plan to engineer neural stem and ensheathing glia cells with expression vectors (CMV-beta actin) for their conditional immortalization (loxP/vmyc), LacZ detection and exogenous controlled expression of neurotrophic factors in vivo (Tet-on/off), as a new therapeutic approach for Parkinson' s Disease.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Colour4CRAFTS - Colour for Combining, Re-engineering, Applying, Futuring, Transforming, Stretching' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Colour4CRAFTS proposal combines a multidisciplinary team of experts from research institutes and R&D companies to carry out studies of bio-based textile colouration in traditional historic perspective and in combination with cutting-edge technologies of colourants biosynthesis and waterless applications techniques. The researchers are top experts in archaeology and history, textiles and colouration, biotechnology and chemistry, art, craft and education. Research combines methodologies of history, artefact research and cultural studies, art and craft research, natural sciences and futures studies. This creates a manifold basis to understand colouration practices in history and craft context profoundly and create innovative state-of-the-art solutions for the futures’ bio-based practices. Multidisciplinary methodologies enable the development of new research methodological openings. Education and communication have important roles as they create and enable interventions for traditions transformation into futures green industries. This research proposal supports and fosters European cultural heritage and the European cultural and creative industries, and it initiates new high quality biocolourant and colouration businesses in Europe. Research aims to foster craft skills in textile colouration, and transform the traditional processes into sustainable cutting-edge processes, which support futures’ green deal objectives; through research provide new profound knowledge of traditional craft colouration practices in Europe and especially in the North Eastern Baltic area, and by combining this knowledge with novel technologies create innovative colourants and colouration practices. This helps increasing sustainability in craft scale colouration and more broadly in industrial scale
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Base-isolation technology for earthquake protection of cultural heritage' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Base isolation is accepted worldwide as one of the most effective strategies for seismic protection of civil structures. The fundamental principle underlying base isolation involves decoupling the structure from the damaging horizontal ground motion, by means of additional flexibility and energy dissipation capability, thereby mitigating the severity of structural vibration and damage during a seismic event.The effectiveness of this innovative technology ¿ typically used to protect the primary structural system in bridges, buildings and the infrastructure ¿paved the way for extending the concept to non-structural elements of strategic importance. Typical examples of non-structural elements include high-value building contents, mechanical and electrical equipment, computer servers, and irreplaceable museum artifacts.The proposed research concerns the protection of museum artifacts against intensive ground shaking through the use of innovative seismic protective systems. Application of base isolation technology to individual artifacts is a viable alternative to seismically isolating the entire building ¿ a significantly more complex and expensive task. The project will concentrate on the evaluation of benefits, as well as ascertaining the limitations, of different types of seismic isolation systems.The seismic performance of base-isolated block-like museum artifacts will be investigated through reliable numerical tools capable of correctly describing the behaviour of such systems. The subject research topic will have great potential for facilitating base isolation as a means of earthquake protection and structural conservation of cultural heritage.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Nonlinear optics at high laser intensities - high order harmonics as a coherent radiation source in the xuv and soft x-ray regions' under Fourth Framework.

assistant: **Concept**

High-order harmonic generation, using high-power, short- pulse lasers, has been shown to be an efficient way to generate coherent radiation in the extreme ultraviolet (XUV) and soft X-ray spectral domain. By using the Ti:S terawatt laser of the Lund Facility (150 mJ, 150 femtosec. at 794 nm) it is possible to go into more detail with characterization and optimization of harmonic generation. At the same time, it is possible to investigate the use of this source to do high-intensity experiments (multi- photon physics) in the XUV. Properly refocusing harmonics, an intensity as high as 10x13 W/cm2 at 100 eV could be reached. This is a completely new domain of modern physics and a kind of experiments which can not be done with other conventional XUV-light sources (synchrotrons, undulators for instance) and represents one important objective of this research project.  In parallel to this, Ti:S laser performances can be upgraded to achieve the pulse peak power of 5 TW from the actual 1 TW and to improve the optical quality of the laser pulse spatial profile.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'INNOVATIVE APPROACHES TO PHENOTYPE MOOD DISORDERS IN MOUSE MODELS'.

assistant: **Innovation**

Major depression is a potentially life-threatening illness affecting 10-15% of the population and causing an enormous economic burden (Euros 120 billions/year in Europe), also due to incomplete efficacy of antidepressants. The most relevant cause of this is the poor knowledge of the neural basis for mood regulation that has to be attributed, among other factors, to the limited information gathered from animal models. The main aim of the present project is setting up an innovative strategy for comprehensive, detailed phenotyping of mouse models of depression. Experimental protocols for investigating behavioural responses involved in the depression phenotype, such as “pessimistic” bias and an altered social behaviour, will be developed in an automated apparatus. These protocols will be used in combination with already validated protocols (e.g. anhedonia, sleep/wake cycle) to obtain a comprehensive, automated and high-throughput phenotyping strategy to assess depression-like behaviour in mice and to screen antidepressant action. Translation research resulting into clinical application for brain research is a central priority in Europe in the context of psychiatric disorders. The high throughput screening combined with strong hypothesis on the evolutionary basis of the behaviours to be modelled can have important consequences on the health, societal and economic burden imposed by major depression, leading to improved drug development. Being able to work in an environment where industry and academia collaborate strongly, such as the host environment, will allow the candidate to better exploit new knowledge for its technological transfer into SME products and will lead to a close cooperation with leading scientists and engineers. Ultimately the opportunity given by this fello
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'FIBRE composite manufacturing technologies FOR the automation and modular construction in shipYARDS' (FIBRE4YARDS).

assistant: **Concept**

To ensure global competitiveness of small and medium European shipyards, a step change is needed. The key to accomplish this relies on overcoming high production costs and low repeatable quality processes which currently inhibit mass production of Fibre Reinforced Plastic (FRP) ship parts. FIBRE4YARDS will bring a cost-efficient, digitized, automated and modular FRP vessel production approach to increase EU shipbuilders’ competitiveness.FIBRE4YARDS’ objective is to match end-users’ needs with targeted advanced production technologies (adaptive molds, ATP/AFP, 3D printing, curved pultrusion profiles, hot stamping, innovative composite connections) from other competitive industrial sectors, and to transfer, adapt and combine them to improve FRP shipyards’ production and maintenance, in a Shipyard 4.0 environment. Real-scale demonstrators will be designed and manufactured to prove feasibility of technologies.Based on the targeted technologies, design and engineering of small/medium-length FRP vessels will be assessed using advanced computational tools. Compliance with the regulatory framework will be ensured, and the necessary personnel training will be provided. All within validated and viable business models targeting a circular and resource efficient maritime sector.This will lead to an improved cost effectiveness of European shipyards and their supply chain, an increased turn-over and a growth of jobs with new 21st century skillsets. Consortium’s high number of SMEs and a FRP shipyard, facilitate direct exploitation in the targeted supply chain. A robust cost-benefit analysis for stakeholders, business plans for successful commercialization and market uptake will be provided, specifically recommending an adequate IPR protection strategy. Environmental impact diminution