RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Rent-a-Spatialist' (RENT-A-SPATIALIST).

assistant: **Innovation**

Through their bodily interaction with the built environment, disabled people are able to detect obstacles and appreciate spatial qualities architects are not attuned to. In architectural practice, however, accessibility of buildings often is considered as a matter of fact, as something people are detached from, taken care of by professionals, instead of something people are exposed or attached to. Legislation translates accessibility into facts by fixing minimum or maximum dimensions, which can be objectively measured by professional accessibility advisors, but offers architects little insight in why a building feature may be problematic or appreciated. Rendering accessibility to the realm of matters of fact thus limits the scope in which disability can be considered a valuable source for design. In this context, we advance a consulting service that mobilizes disabled people’s spatial experience to inform architects on how to make a particular building or site more inclusive, i.e. respectful of the diversity in people’s abilities and conditions. The value concept of the consulting service combines three elements: 1. the spatial experience of disabled persons, so-called spatialists; 2. the set up of embodied dialogues with a selection of spatialists in situ; 3. an analysis report that documents the disabled person’s experiences during the visit in a narrative way. This provides architects nuanced insights in why disabled people dislike or value a certain building feature, beyond merely indicating that it is (in)accessible. The idea to be taken to proof of concept is that this consulting service can be marketed commercially to inform architects and other relevant  actors in the design and building process. Such a service is expected to contribute to a more inclusive built
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Mutation and Recombination in the Cattle Germline: Genomic Analysis and Impact on Fertility'.

assistant: **Innovation**

Mutation and recombination are fundamental biological processes that determine adaptability of populations. The mutation rate reflects the equilibrium between the need to adapt, the burden of mutation load, the “cost of fidelity”, and random drift that determines a lower limit in achievable fidelity. Recombination fulfills an essential mechanistic role during meiosis, ensuring proper chromosomal segregation.  Recombination affects the rate of creation and loss of favorable haplotypes, imposing 2nd-order selection pressure on modifiers of recombination.It is becoming apparent that recombination and mutation rates vary between individuals, and that these differences are in part inherited.  Both processes are therefore “evolvable”, and amenable to genomic analysis.  Identifying genetic determinants underlying these differences will provide insights in the regulation of mutation and recombination. The mutational load, and in particular the number of lethal equivalents per individual, remains poorly defined as epidemiological and molecular data yield estimates that differ by one order of magnitude. A relationship between recombination and fertility has been reported in women but awaits confirmation.Population structure (small effective population size; large harems), phenotypic data collection (systematic recording of > 50 traits on millions of cows), and large-scale SNP genotyping (for genomic selection), make cattle populations uniquely suited for genetic analysis. DAMONA proposes to exploit these unique resources, combined with recent advances in next generation sequencing and genotyping, to:(i) quantify and characterize inter-individual variation in male and female mutation and recombination rates,(ii) map, fine-map and identify causative genes underlying QTL for these f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Adoption of best practice technology cases'.

assistant: **Innovation**

The DEMON Proposal is submitted by a network of 14 organisations from 8 European countries to address the identified need to strengthen the innovative capacity of the European industrial system by fostering the creation of business and services built on emerging technologies and new market opportunities".The key elements of the proposal are:(1) To link thematic networks and technology transfer organisations into a Demonstration Network (DN) to enhance the potential for "translating scientific knowledge into innovation, and the diffusion of technologies developed under RTD projects" as envisaged in the Competitive and Sustainable Growth Programme.(2) To facilitate wider dissemination of RTD results to industry in specific sectors and areas of knowledge.(3) To stimulate the use of technologies and methodologies developed in RTD projects through case studies demonstrating the feasibility of the technologies and best practice in their use."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Development of an in vitro cellular model to predict the immunological impact of dietary proteins' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

As the world population continues to grow and a shortage of protein supply is foreseen, there is a need to identify new and sustainable protein sources. While these alternative proteins must be of high nutritional quality, they also need to be safe for consumption. Dietary proteins and their digestion products can influence a number of regulatory systems, including the immune system. By interacting with elements of the immune system, proteins can help balance and stabilize immune responses, but may also trigger adverse effects such as allergic reactions. While the effects of proteins and peptides on the adaptive immunity have been examined in a number of studies, few have studied how these molecules are absorbed through the small intestine and interact with the innate immune system. Since, in order to trigger an immune response proteins must first be transported across the intestinal wall and interact with the innate immune system, understanding these processes is key to determining the immunological effects of protein consumption. The aim of the proposed project is to develop an in vitro model to evaluate the impact of dietary proteins on the immune system. This research will first examine the uptake of proteins and their digests across the intestinal wall using cellular models mimicking the intestinal epithelium and subsequently investigate the effect of the absorbed proteins/peptides on the immune system’s key players, including the dendritic and T cells. The model system that this research aims to develop could help shed light on the roles played by dietary proteins in regulating intestinal immunity and serve as a tool to evaluate the immunological properties of novel and sustainable proteins. Thus, this research is of relevance not only to the European food industr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Managed Aquifer Recharge Solutions Training Network'.

assistant: **Concept**

Managed Aquifer Recharge (MAR) – storing water in aquifers during times of excess – is a key strategy to enrich groundwater resources in water scarce regions by providing intermediate storage, addressing the typical mismatch between water demand and availability. It can help to mitigate the effects of climate change, and to support water-related environmental services. MAR is, however, characterized by complex interaction of physical, biological and hydrochemical processes influencing water quality and the sustainability of infiltration rates. Individual processes are in principal known, but there is a significant knowledge gap on how they are linked and affect each other. An in-depth understanding of their interplay can lead to MAR systems tailored for best performance in terms of water storage, water polishing goals, infiltration rates, economic viability, and adaptation to climatic change.MARSoluT addresses this knowledge gap by a collaborative effort in a multi-disciplinary team. Activities are organized around the existing field sites of previous EU FP7 project MARSOL that are already highly characterised and instrumented to allow further in-depth studies and experimental approaches. This will lead to new insights into the complex and coupled processes at MAR sites and will help to optimize MAR design and operation, and thereby minimizing risk of MAR failure. Excellence in research and technological innovation are ensured by involving partners from renown research organizations as well as SMEs and industry partners with a strong background in the water sector.MARSoluT ESRs will get hands-on experience at various MAR sites while tackling specific MAR-related research topics in an interdisciplinary team. MARSoluT ESRs will become experts on the tailored planning of M
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Safe and ecologically sound front, side, rear and bottom sides for articulated lorries', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The scientific and technical objectives of this research proposal concern the development of safe and ecologically sound fenders for lorries which are not fatal until speeds up to 40 km/h. Research is required to characterise the material properties, needed for the development of synthetic light-weight fenders with a high power absorption capacity for collisions. In addition, the R&D-activities are aimed at minimising the environmental effects.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Dynamic Interplay between Energy and Memory' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Understanding the links between neuronal plasticity which underlies memory and energy metabolism is a major goal of brain studies. The brain is a main energy consumer and the central regulator of energy homeostasis, and it prioritizes its own supply over peripheral organs. Interestingly, our work demonstrates that the brain is also able to regulate its own activity under energy shortage to favor survival.The EnergyMemo project proposes to perform in drosophila an original integrated study of the interplay between energy metabolism and olfactory memory at the molecular, cellular and circuit levels. On the ground of important preliminary results, we will investigate in vivo how and why the energy flux increases during long-term memory encoding, and how brain plasticity is regulated by the energy supply. We will focus on three major challenges:* Objective 1: to improve our understanding of brain physiology, we will characterize in drosophila neuronal circuits that integrate information about the brain energy status. * Objective 2: to understand how abnormal levels of energy can affect the brain, we will analyze how the energy level shapes the functioning of the olfactory memory center.* Objective 3: to characterize how energy stores are mobilized during memory formation, we will investigate how the neuronal and glial networks interact to manage the energy fluxes.This multidisciplinary project will benefit from our team's longstanding experience in behavioral studies and leadership in live brain imaging, in addition to the unmatched descriptive power of drosophila neuronal circuits at the single-neuron resolution. Successful completion of this program will surely uncover mechanisms of brain function conserved across species, and should bring-up new ideas about how deregulat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Hydrographic monitoring - neva bight' (HYMNE) targeting Fifth Framework.

assistant: **Abstract**

The river Neva flows into the Gulf of Finland via the Megabyte. Its fresh water discharge ranks first place for the entire Baltic Sea transporting the freight of the metropolitan area of St. Petersburg. The anthropogenic impact tithe ecological and economical resources of the hydrosphere underlies a continuous variation especially due to accidents. For the mitigation of the pollution within this region it needs a consequent and comprehensive management of the resources of the hydrosphere on the basis of an operational monitoring, which will be provided by HYMNE linking modern observation and prediction techniques. This will be evaluated during the spring time, when the river Neva reaches its seasonal maximum discharge rate. The monitoring strategy will be established together with and further exploited by the environmental administration of St. Petersburg.The objective of HYMNE was to provide the scientific basis for an operational hydrographic monitoring and prediction system as a cost effective tool for the management of the environment. Its possible application was demonstrated for the Neva Bight; it is possible to adapt this tool to other threatened areas. Remote sensing data were adapted to provide an operational monitoring of the regional hydrosphere with a high spatial and temporal resolution. To assess external impacts, satellite optical, IR (infra-red) and radar instruments were used to monitor hydrographic and environmental parameters on a large scale. Locally situated shore based radar devices observed the water transport rates, ice movements, wind, waves as well as small-scaled eddies. Operational numerical models, which were adapted to the region of the Neva Bight, were used for coupling the forecasts for water circulation, ice coverage, river level and eco
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Investigating the effects of past global ocean acidification on marine ecosystems: A novel multiproxy approach' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The on-going acidification of modern oceans is a major issue of concern because it may have serious consequences for the survival of shelly marine invertebrates as the 21st century progresses. This is driven by anthropogenic CO2 release and the additional consequence of global warming is predicted to produce ocean de-oxygenation within a century. A better understanding of such effects will come from study of past ocean acidification and anoxic events but this objective is hampered both by poor constraint of ancient pH and redox values. This study aims to develop a new stable isotope technique – using Ca isotope fluctuations – to monitor ocean carbonate budgets and to evaluate the S isotope record of the oceans, a system primarily affected by ocean redox and evaporite burial.  This approach will be applied to the end-Permian catastrophe, the greatest mass extinction of all time, to evaluate the hypothesis that the marine biotic crisis was caused by acidification and anoxia. Comparisons will be drawn with the non-steady state oceans of the late Precambrian Snowball Earth world when similar perturbations in ocean chemistry produced similar rock types to those seen in the aftermath of the Permian extinction. This uniquely, multi-pronged geochemical approach will allow coupled box modelling of the marine Ca and S budget and thus for the first time it will be possible to relate changes in these systems to oceanic oxygenation and pH levels and the contemporaneous mass extinction.The multi-pronged geochemical approach of this research will ultimately help to better constrain the timing and future effects of the anthropogenic emissions of CO2 on ocean acidification, marine biologic activity and global biogeochemical cycles.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Groups, Actions and von Neumann algebras'.

assistant: **Objectives**

This research project focuses on the structure, classification and rigidity of three closely related objects: group actions on measure spaces, orbit equivalence relations and von Neumann algebras. Over the last 15 years, the study of interactions between these three topics has led to a process of mutual enrichment, providing both striking theorems and outstanding conjectures.Some fundamental questions such as Connes' rigidity conjecture, the structure of von Neumann algebras associated with higher rank lattices, or the fine classification of factors of type III still remain untouched. The general aim of the project is to tackle these problems and other related questions by developing a further analysis and understanding of the interplay between von Neumann algebra theory on the one hand, as well as ergodic and group theory on the other hand. To do so, I will use and combine several tools and develop new ones arising from Popa's Deformation/Rigidity theory, Lie group theory (lattices, boundaries), topological and geometric group theory and representation group theory (amenability, property (T)). More specifically, the main directions of my research project are:1) The structure of the von Neumann algebras arising from Voiculescu's Free Probability theory: Shlyakhtenko's free Araki-Woods factors, amalgamated free product von Neumann algebras and the free group factors.2) The structure and the classification of the von Neumann algebras and the measured equivalence relations arising from lattices in higher rank semisimple connected Lie groups.3) The measure equivalence rigidity of the Baumslag-Solitar groups and several other classes of discrete groups acting on trees.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'HEALTHCARE ALLIANCE FOR RESOURCEFUL MEDICINES OFFENSIVE AGAINST NEOPLASMS IN HEMATOLOGY – PLUS'.

assistant: **Innovation**

Haematological malignancies (HM), also known as blood cancers, are a heterogeneous and complex group of multicausal diseases that can’t be easily diagnosed nor treated. Nowadays most treatments are extremely complex, and advances in patient diagnosis and therapies slow due to the low number of patients per centre. Thus, there is a need to harmonise, store, and analyse the current HM information to speed-up and support the decision-making process for patients’ access to new therapies. HARMONY PLUS takes advantage of the capabilities of the HARMONY Big Data platform to match these unmet needs by expanding its scope to incorporate myeloproliferative neoplasms, including chronic myeloid leukemia, polycythaemia vera, essential thrombocythaemia, and myelofibrosis; and lymphoproliferative disorders, including Hodgkin’s lymphoma, Waldenström macroglobulinemia and all the other rare HMs not covered by HARMONY Project. In parallel, HARMONY PLUS will continue to refine and define the Core Outcome Sets (COS), especially for these new HMs to ensure the use by researchers of useful common outcomes relevant to all stakeholders. As previously accomplished in HARMONY, HARMONY PLUS is committed to pursue the maximum ethical and legal requirements, particularly to ensure patient’s right to privacy.Data-driven research within Europe will be enhanced by converting the current HARMONY platform into an Integrated Services Platform to serve as a valuable tool to support clinical trial design and use of available data as a control arm. This platform, combined with a HaemoDatabank repository with information about HMs patient biological samples across Europe, will facilitate a more efficient research and clinical trial design, and consequently will promote collaborations with recognised database