RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Remote sensing of large wildland fires in the european mediteranean basin.' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

SUMMARY Remote Sensing of large wildland fires in the European Mediterranean Basin (MEGAFiReS) The objective of this project is to establish an integrated framework to analyze satellite remote sensing images for operational manaqement of large wildland fires in the Mediterranean countries of the European Union (EU). Three research objectives will be pursued: 1. To develop methodologies for fire risk rating and mapping, on both global and local scales, based on satellite remote sensing and Geoqraphic Information System (GIS) techniques. Global maps of fire risk for all the EU Mediterranean countries will be produced, considering shortterm and lonq-term risks. For the short-term risk, the temporal and spatial variation in fuel moisture contents will be estimated from meteoroloqical and Earth resources satellites. Long-term or structural risk will be generated by integrating satellite data within a GIS specifically designed for fire risk mapping. Special attention will be given to the spatial modelling of the human component, both using GIS and remote sensing techniques. 2. To test the application of satellite remote sensing data to fire detection and fire fighting. Maps of burning areas for all the EU Mediterranean countries will be generated. Minimum size of a fire to be detected by current satellite sensors will be determined considering the special characteristics of Mediterranean wildlands. Satellite images on the evolution of large fires will be compared with the spatial simulation of fire-growth derived from GIS techniques. Real-time acquisition of satellite images and transmission to fire fighting personnel to inform them about fire front propagation will be tested. 3. To inventory, map and assess the effects of large forest fires in the Mediterranean countries of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The formation of massive galaxies: the roles of dust-obscured starbursts and AGN activity' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

I propose an integrated programme to determine the role of dust-obscured starburst activity and AGN growth in the formation and evolution of  galaxies.  This programme will exploit three, new cutting-edge observational facilities: the SCUBA-2 submillimetre camera, which will provide the first panoramic surveys of luminous, but highly obscured, sources out to the highest redshifts;  the Atacama Large Millimeter Array (ALMA), which will provide sub-kpc imaging of the distribution of dust and gas within these sources to understand the physics of their activity;  the e-MERLIN radio telescope, which will map the distribution of star formation and AGN activity at sub-kpc scales in these systems.  I lead major international surveys on all three facilities and I propose to develop and combine these projects to provide a single focused programme to understand the processes which trigger obscured activity at high redshifts and their role in determining the properties of galaxies at the present day.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Oncogene-induced DNA damage as driver of B cell lymphoma genesis' (OncIndLymph), addressing dissemination and exploitation.

assistant: **Impact**

Recurrent oncogenic chromosomal rearrangements are a hallmark of lymphoid malignancies and are considered to be the driving force in tumor survival and progression. While oncogenes typically induce uncontrolled proliferation, they also induce metabolic stress and constitutive DNA damage. Hence, at the time of diagnosis tumor genomes are typically highly mutated. Not surprisingly, forced expression of an oncogene in healthy cells results in oncogenic stress leading to apoptosis or cell cycle arrest. This phenomenon is considered as an initial cellular barrier to prevent malignancy. However, tumor cells did pass this barrier, and it is assumed that they did so by acquisition of additional defects that allow them to tolerate oncogene expression. Oncogene-induced DNA damage is likely to initiate these transforming genomic defects and may further contribute to tumor progression. The proposed study is designed to address this subject. The goals of the proposed study are a) to identify and functionally characterize oncogene-induced DNA damage in a genome-wide manner and b) to uncover resulting genomic lesions that mediate tolerance to oncogenic stress and are required for initiation of malignancy. The proposed work will lead to a better understanding of tumor development and opens the opportunity for the development of new treatment strategies for human leukemia and lymphoma based on reactivation of oncogene-induced lethality in cancer cells.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Functionality Rotation-Mediated Solvent Separations in Nanochannel Membranes'.

assistant: **Innovation**

Nanochannel membranes with 1-nm/sub-1-nm channels provide an energy-efficient and sustainable way of solvent separations for global process-based industries that operate on solvent mixtures. Channel modifications by binding selective functionalities are a widely adopted strategy to improve membrane selectivity, but it often compromises target solvents permeability, presenting a persistent and undesired trade-off dilemma. This is largely due to the relatively fixed position of the functionalities, whose steric hindrance unavoidably retards molecular transport at this scale. In contrast to previous designs, this project aims to develop a novel nanochannel membrane featuring rotatable functionalities. It takes advantage of functionality dynamics - rotations - to facilitate target solvent transport while blocking competing solvent, effectively overcoming the trade-off. The demonstration and verification of this idea are based on 3 steps, including (1) development of a prototype membranes using a 2D layered MXene assembly as backbone and ammonium ions (NH4+) as functionalities due to their intrinsic ultrafast rotation in solvents (e.g., water); (2) evaluation of the solvent separation performance (e.g., water-ethanol) of such membranes against MXene membranes functionalised by slow-rotating ions or no ion (pristine); (3) elucidation of the relation between functionality rotation and solvent transport/separation by coupling experimental results, key characterizations, and computational modelling.Project success will advance the state-of-the-art in practical, conceptual, and mechanistic aspects. A high-performance solvent separation membrane that breaks trade-off will be fabricated. A new nanochannel membrane design principle involving functionality dynamics will be establishe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Extreme-Ultraviolet Meta-Optics for Attosecond Microscopy' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Extreme ultraviolet (EUV) light sources have matured, both in brightness, as well as in producing ever shorter attosecond light pulses. Contrary, transmissive EUV optics remain sparse due to material absorption. Thus, EUV microscopy today focuses mainly on lensless techniques or secondary observables such as photoelectrons. EUVORAM (Extreme-Ultraviolet Meta-Optics for Attosecond Microscopy) will experimentally demonstrate that meta-optical devices are realizable in the EUV using a novel design approach and that they can solve the current lack of transmissive EUV optics. By emulating the spatial phase profiles of aspheric lenses, we will fabricate focusing meta-optics yielding near-diffraction limited microfoci in the EUV. In combination with contemporary attosecond pulse sources based on laser-driven high-harmonic generation, these meta-lenses will enable high-numerical-aperture EUV focusing that maintains attosecond pulse durations. EUVORAM will exploit this capacity to build a light microscope that unifies attosecond time and nanometer spatial resolution. After its demonstration, we will apply this microscope to isolate the ultrafast hot electron dynamics and sub-nanometer charge transfers in individual plasmonic core@shell nanoparticles using spatially resolved attosecond transient absorption spectroscopy.EUVORAM will be one of the first projects connecting attosecond science and dielectric meta-surfaces. The planned EUV meta-optics and their novel design will undercut the current short-wavelength limit of meta-surface optics by a factor of four and thus directly redefine the state-of-the-art. The project will push lens-based microscopy to unprecedented time resolutions and at the same time allow hyperspectral attosecond imaging. The latter will free attosecond exper
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Thermoelectric cooling using innovative multistage active control modules' (THERMICOOL) under Seventh Framework.

assistant: **Objectives**

The aim of this work is to develop an innovative TEC for avionic application with maturity level TRL5, low power consumption and high efficiency and a combination of thermoelectric materials and energy harvesting techniques. The work will be based on the experience gained in previous works of the research team, concerning marine (ECOMARINE) and avionic (RENERGISE) environments and it will investigate advanced TE materials with ZT >>1, in multistage module configurations to cope with the harsh avionic environment and novel active control schemes to achieve high COP values.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'A network of excellence for distributed, trustworthy, efficient and scalable AI at the Edge'.

assistant: **Concept**

The proposal focuses on the Next Generation AI topic of the call HORIZON-CL4-2022-HUMAN-02-02. The vision of dAIEDGE Network of Excellence (NoE) is to strengthen and support the development of the dynamic European edge and distributed Artificial Intelligence (AI) ecosystem as an essential ingredient in the growth and competitiveness of European industrial sectors. The dAIEDGE Network aims to reinforce the research and innovation value chains to accelerate the digital and green transitions through advanced edge AI technologies, applications, and innovations, building on Europe's existing assets and industrial strengths. In parallel, it will fortify the edge AI research and industrial communities through technological developments beyond state of the art and become a dependable and strategic pillar for the European AI Lighthouse. This will be achieved by mobilising and connecting the European AI and edge AI constituency, the relevant stakeholders, European partnerships, and projects, to provide roadmaps, guidelines and trends supporting the next-generation edge AI technologies. The key aim is to support and ensure rapid development, market uptake and open strategic sovereignty for Europe in the critical technologies for distributed edge AI (hardware, software, frameworks, tools). The dAIEDGE NoE will play a catalyst role in building a solid edge AI virtual network of research facilities and laboratories to benefit the European research and industrial community. The NoE multidisciplinary concept provide an arena for matchmaking, exchanging ideas, tools, and services, by bringing together the leading research centres, AI-on-demand platforms, digital innovation hubs, AI projects and initiatives. The ultimate goal for the dAIEDGE NoE is to support Europe to become a global ce
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Impact of increasing CO2 on trophic transfer efficiency in marine food webs' (2002-2006).

assistant: **Concept**

Current models predict a twofold increase in atmospheric CO2 and associated decrease in oceanic pH by about 0.4 units until the end of present century. How this drastic change will affect food webs and trophic transfer in the coastal ocean is unforeseen. We propose to study the effects of these changes on phytoplankton biochemical composition and concurrent effects of potentially altered food quality on secondary producers in the marine systems.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Efficient and Effective Evaluation of Information Retrieval Systems' (EFIREVAL) under Seventh Framework.

assistant: **Objectives**

Information Retrieval (IR) is a ubiquitous technology. The range of tasks and information collections IR systems are applied to is ever growing. However, the ability of researchers and developers to build high quality searching systems for new environments is not keeping up with the growth in potential application areas. As a consequence, search system quality is degrading: users of bespoke systems expect a Google-like experience of swift high quality retrieval; instead they commonly get slow sub-standard results. The key reason for this failing is the profound lack of testing resources that capture the unique and complex environments different retrieval systems are deployed in. The cost of building test resources is prohibitively expensive. Consequently, researchers are unable to assess the effectiveness of new ideas in such environments, search engine vendors struggle to tune their systems to the particular needs of their customers, customers looking to choose between competing search products do not have the resources to measure which system will better serve their needs. This project will address this problem by developing a new evaluation paradigm for search, which will, (1) establish an efficient and reliable test resource construction methodology, (2) develop a framework to adapt such resources to a wide variety of retrieval scenarios, and (3) extend the current evaluation paradigm to incorporate additional information about the different retrieval scenarios and users' activities. With such a methodology, researchers will develop and test a far richer set of approaches to search; companies will provide systems better suited for customer needs; organizations will be able to test more thoroughly their existing installed systems. Ultimately, developing the new parad
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Recapitulating and preventing epileptogenesis in early human brain network development' (Epi-Stop) under Horizon Europe.

assistant: **Objectives**

Epilepsy is one of the most common neurological disorders, yet current treatments fail to prevent seizures in more than a third of cases (~37%). Most drug targets focus on seizure suppression; however, these are symptoms of abnormal developmental changes in the neural network. The processes that give rise to epileptic brain regions are summarized by the concept of epileptogenesis. Therefore, preventing epileptogenesis is critical for long-lasting seizure freedom. Studying epileptogenesis is challenging, as the developmental processes involved in it occur before birth during neurodevelopment itself. Recent progress in stem cell models, however, has the potential to change this. The Knoblich Lab pioneered the use of human cerebral organoids to model disease in-vitro, such as Tuberous Sclerosis (TSC). Cortical tubers are the source of drug-resistant epilepsy (DRE) in TSC, which our recent study (Eichmüller et al., Science 2022) uncovered to originate from a specific precursor cell type; CLIP cells. Strong preliminary evidence shows that pathological processes are occurring in TSC organoids which recapitulate epileptogenic electrical biomarkers called high frequency oscillations (HFOs).In this proposal I will utilise our brain organoid model to understand human circuit-level dysfunction in epilepsy and identifyevidence-based causal treatment for epileptogenesis prevention. Therefore, I plan to classify stages of epileptogenesis in human brain TSC organoids using large-scale signal features and in-depth molecular characterizations to identify biomarkers for abnormal circuit initiation and progression. I will reveal stage-specific druggable targets for epileptogenesis and then test novel anti-epileptogenic compounds on pathological network activity prevention. Together, this
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'geoBone: A Unique Mineral Supplement for Bone Health and Prevention of Osteoporosis Sustainably Produced from Geothermal Resources through a Ground-breaking Process.' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The progressive ageing of the population is coming accompanied by a long list of chronic conditions. Among them is the lossof bone density, a natural process that begins after the age of 30. The risk of fracture grows proportionally to the disruptionof the bone architecture, advancing from minor osteopenia to severe osteoporosis, which is a global public health concernthat affects today 200 million people. In the EU, the costs derived from osteoporotic fractures reach today €37billion.Although the reason for bone loss in the adult age is poorly understood, it is believed to be due to a lower capability toabsorb minerals from our diet. Thus, in the adult age clinicians recommend the intake of mineral supplements to cover forthe dietary insufficiency. Although most bone health supplements are based on calcium, it is the mineral silica the one withhigher impact on bone mineralization. Despite its recognized effects on bone and connective tissue, its market uptake hasbeen long hindered due to the low concentration, low bio-availability, inadequate presentation and poor absorption rates ofcurrent supplement products. In response, we at geoSilica have developed geoBone, a silica-rich drinkable supplement thatoffers this mineral in high concentrations and in the highest bio-absorbable form. Its properties result from our uniqueproduction method, which purifies silica from the mineral rich water byproducts of geothermal power plants. After validatingthe concept and production sustainability, this project aims to take geoBone to market readiness by finalising itsdevelopment & industrialising its production process. The Feasibility Study planned in Phase 1 will serve to warrant theproject from all technical, commercial & financial standpoints. Besides bringing huge benefits for s