RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Dignity For Irregular Migrants in EU Farm2Fork Labour Markets', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

DignityFIRM contributes to improving conditions of irregular migrants (IM) working in Farm to Fork (F2F) labour markets in four EU member states (IT, NL, PL, SP) and two associated countries (MO, UA). To derive structural recommendations for improvements, we analyze regulatory infrastructures that govern these conditions distinguishing five influential spheres of stakeholders at the EU, national, and local levels, and at the level of employers and IM themselves. The focus on IM in F2F labour markets is timely given the instrumental role of these industries in securing EU livelihoods, the high systemic dependency on IM that coincides with persistent group vulnerabilities. By providing knowledge and innovative tools to improve regulatory infrastructures, this project enhances IM’s access to basic rights and services, and improves their precarious working conditions. Doing so, we contribute to systemic resilience of F2F industries and the EU’s ambitions for social and economic transformation. Our project adopts a mixed-method research approach, that includes a special focus on the division of labour in F2F markets with respect to gender, ethnicity, socio-economic status, health and safety. Doing so, we provide new knowledge on 1) the multidimensional regulatory infrastructure and the conditions of IM therein, 2) their access to basic rights and social services, and 3) employer reliance on IMs. We build on our analysis of the current situation, and work towards innovative solutions by developing Dignity tools in co-creation with stakeholders across the five stakeholder spheres. We propose group sensitive policy measures at EU, national, and local level, across four policy domains: migration management, EU pillar social rights, labour market sustainability and corporate soci
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Patchy colloidal particles: a powerful arsenal for the fabrication of tomorrow new  super-molecules . A theoretical and numerical study of their assembly processes', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

An unprecedented development in particle synthesis  is  providing methods to generate high yield  quantities of nano- and micro-particles of  different shapes, compositions, patterns and functionalities and  an unprecedented diverse spectrum of particle  patchiness, significantly extending the naturally available choices.  These methods draw from the diverse fields of chemistry, physics, biology, engineering and materials science, and, in combination, provide a powerful arsenal for the fabrication of new particulate building blocks, the molecules of tomorrow materials, self-assembling into molecular-mimetic and unique structures, fluids, and gels made possible solely by their design.The new  particles offer the possibility to go beyond the spherical interaction case, to move from the colloidal atom to the colloidal molecule --- providing valence to colloids --- and to further  strength  the analogies between colloids and globular proteins.  The present theoretical and computational project aims at providingnew ideas for  developing   effective methodologies of  bottom-up manufacturing, at providing  the scientific community with the background  necessary to fully control the self-assembly of these new building blocks as well as solutions to relevant condensed-matter physics problems.  The project also aims at developing realistic models of DNA-functionalized nano and micro particles, presently the most promising and versatile building block of  bio-colloid materials.  Understanding the assembly of patchy particles will  offer fine control over the three-dimensional organization of materials, as well as the combination of different materials over several length scales, making it possible to design a spectrum of crystal polymorphs and self-assembled ordered and disordered
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Innovative Reliable Nitride based Power Devices and Applications' (InRel-NPower).

assistant: **Concept**

The main objective of this proposal is to develop reliable GaN-based power devices and systems for high and medium power electronics targeting industrial and automotive applications and bringing the GaN power devices another step towards the wide usability in the energy saving environment to further tap the full potential which this new material brings along.This proposal addresses two subjects, one of which is medium power (till 10kW) GaN-on-Si based lateral HEMT structures (Normally OFF devices), with special focus on high reliability, which is still a major blocking item to allow wide-spread market adoption.  Hence, the impact of the GaN material quality, in combination with the device layout in view of long-term reliability will be addressed. The project aims an in-depth reliability study and qualification strategy development whereby the study of the impact of dislocations and other structural disturbances inside the materials on the long term device reliability will be specifically addressed. In addition, this proposal aims to demonstrate new device concepts with increased robustness and reliability, which will be realized, evaluated and tested thoroughly. This will demonstrate how it is possible to overcome the known limitations of the GaN on Silicon technology, like e.g. the vertical leakage, trapping phenomena and/or breakdown of lateral HEMTs and the p-GaN gate related reliability  issues. The current proposal also contains the development of novel device architecture (dual channel, substrate removal, e-mode), as well as the exploration of new material systems (Aluminum Nitride (Al-based) devices) which can also largely contribute to overcome drawbacks of the GaN on Si technology. The applicability of the novel GaN-on-Si concepts in form of an industrial inver
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Cell-cell interactions critical to ILC3 function in the human gut' (GutILC3), addressing dissemination and exploitation.

assistant: **Impact**

Inflammatory bowel disease (IBD), conferring a dramatically increased risk for development of colorectal cancer (CRC), results from an inappropriate inflammatory response to intestinal microbes in a genetically susceptible host. However, the exact etiology of IBD is unknown. Building up on high impact papers from the host group reporting on the recently discovered innate lymphoid cells (ILCs) as key players in mucosal inflammation, I now aim to unravel the role for ILCs in IBD and CRC. Interestingly, while the IL-22 producing ILC3 seem to be crucial in maintaining intestinal homeostasis, the IL-17 and IFN-gamma-producing ILCs can cause inflammation in a mouse model of colitis and are present in human IBD. Furthermore, ILCs were recently described to be involved in modulating immune responses, by interacting with CD4+ T cells and mononuclear phagocytes in the mouse intestine. I aim to identify critical pathways in the crosstalk of ILC3 with other immune cells in the human intestine. The ultimate purpose is to assess how these interactions affect immune homeostasis and disease progression in IBD and CRC. We will pinpoint crucial interaction molecules and cellular processes that can be used for monitoring current therapies as well as finding new therapy targets for IBD and CRC.This truly translational proposal utilizes, in an optimal manner, unique state-of-the-art techniques and patient materials to provide novel insights into the etiology of IBD and CRC. The excellent track record of the hosting group, the highly suitable infrastructure provided by the host institution and my own extensive research experience ensures a high degree of feasibility. Furthermore, this project provides excellent training opportunities, skill advancement possibilities and career prospects for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'LANGUAGE AND JOINT ACTION' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

A conversation is a clear example of joint activity. However, little is known how the more basic sensori-motor processes underlying joint action apply to the complex interwoven between language production and comprehension during communication. The present project aims to contribute to our understanding of language as a joint action by exploring how the two fundamental processes that contribute to the success of any joint action, namely prediction and monitoring, are engaged during verbal communication.  To do so, the temporal dynamics of the different levels of representation underlying speech production (conceptual, lexical and phonological), will be tested in the listener during prediction and monitoring of other’s speech. By means of five experiments, we aim at providing response to three specific research questions regarding prediction and monitoring of other’s generated speech. Firstly, we will explore how the language production, as a form of action, is involved in predicting other’s to be generated words. Second, we will explore the nature of those predicted representations. And finally, we will focus on exploring the monitoring processes engaged in detecting errors in other’s word production. Behavioral and EEG/ERP measures will help us to answer these questions. Considering the relation between language and action, the present work will help to determine how the basic sensory-motor skills apply to the complexities of language. Finally, answering these questions will contribute to enlarge our understanding of how language works during verbal communication.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Defined co-immobilization by DNA binding protein tags' (DECODEB) targeting Seventh Framework.

assistant: **Abstract**

Defined spatial distribution of proteins plays a major role in nature, like structures for bacterial cell mobility (Escherichia coli’s flagella), capsid structures of viruses, structures for the controlled segregation of chromosomal DNA both in eukaryotic and prokaryotic cells, a large array of membrane protein complexes (e.g. protein transporters and nutrient transporters) and the assembly of channeled metabolic pathways among many others. All these diverse and fundamental processes are the result of the evolution of very specific and controlled spatial organization of multiple proteins. Defined spatial distribution also plays a major role in many biotechnological applications of proteins, from the immobilization of antibodies on the surface of an electrode for their use in biosensors to the creation of nanostructures through biotemplating. A wide variety of approaches have been developed in order to allow the easy immobilization of proteins, ranging from electrostatic interactions and direct covalent linkage to high affinity non-covalent interactions (e.g. streptavidin/biotin). In order to facilitate the generation of more complex synthetic quaternary protein structures (on surfaces and in solution), we propose the development of a protein fusion tag system that will enable the controlled and orderly precise co-immobilization of proteins by means of protein-DNA interactions. This project aims to take advantage of the highly developed methodologies that currently exist and allow the synthesis and immobilization of DNA with ease and use them as a means for controlled protein co-immobilization. Specifically, to achieve this objective, we propose to develop a panel of high affinity DNA binding proteins with different sequence specificities to be used as fusion tags and pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Society in Innovation and Science through CODEsign' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Public Engagement (PE) and Responsible Research and Innovation (RRI) have emerged, in the last decade, as the results of policies and initiatives demanding the early involvement of multiple actors, including the public, in science and innovation. Nevertheless, the early engagement of actors is facing many challenges, and PE rarely goes beyond the stage of consultation. On the other hand, the integration of co-creation in European STI policy and programmes faces barriers such as: scarce understanding of co-creation among researchers and policy makers; “sectorialised” approach to STI policy making; lack of effective knowledge to cope with constraints that hamper the co-creation process.The introduction of design methodologies and tools is emerging as a valuable approach to deal with these problems, as design has been already recognised as key to operationalise co-creation in different fields. Thanks to an iterative process centred on prototyping - co-design effectively support co-creation to move from the ideation of new solutions and policies to their implementation.Given this framework, SISCODE aims: to understand co-creation as a bottom-up and design-driven phenomenon that is flourishing in Europe (in fab labs, living labs, social innovations, smart cities, communities and regions); to analyse favourable conditions that support its effective introduction, scalability and replication; and to use this knowledge to cross-fertilise RRI practices and policies. To reach this aim SISCODE will: run a European study to compare co-creation ecosystems and describe effective dynamics and outcomes of the integration of society in science and innovation; experiment with design as a new system of competences capable to support the development of implementable RRI and STI solutions an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Converting Facilities Network for accelerating uptake of climate neutral materials in innovative products', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Convert2Green will establish an Open Innovation Test Beds (OITB) that enables material suppliers to integrate their innovative, circular and carbon neutral material solutions to the European Key Value Chains: Clean Autonomous Vehicles; Smart Health; Industrial IoT; Low Carbon Industry and Clean Energy. Thus, Convert2Green will provide innovative material suppliers new business opportunities in these value chains. Convert2Green will complement the European Open Innovation Ecosystem with services not present in other OITBs by now: (1) Complete Eco-Impact Analysis from Raw Material to Product as a service including LCA, LCC, Safety and Toxicity; (2) TRL4 to 7 Process Chains for Smart Textiles and Processing of Fiber based materials; (3) TRL4 to 7 Process Chain for Electronics on Plastic, Paper and Textiles; (4) Pilot Facilities for recovering critical raw materials from products; (5) Pilot Facilities for Processing of recycled plastics and composites, (6) Pilot facilities manufacturing of (nano)fibers and composites from bio-sources. Furthermore, Convert2Green will be the first OITB that establishes and provides to the OITB ecosystem: (1) procedures and contract models for licensing of joint IP through the Single Entry Point(s); (2) multilingual digital platform to integrate and jointly promote the service portfolio of all OITBs as well as to interconnect relevant stakeholders and to allow fully digital project and knowledge management and (3) novel financing models for SME combining a trust generating due-diligence structure with project based investment models and crowd-invest opportunities to accelerate market entry in all value chains given above. Convert2Green will integrate its services with the whole European Innovation Ecosystem and continues the series of OITB eve
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Targeting microRNAs for ColoRectal Cancer Therapy' in the context of a Seventh Framework call.

assistant: **Objectives**

MicroRNAs are small non-coding RNAs involved in cell homeostasis and carcinogenesis. MicroRNA deregulation is associated with colorectal cancer (CRC) progression. My study proposes to identify genetic and epigenetic events leading to microRNAs deregulation and use them as targets for drug development. My research proposal will address two important questions. First it will assess the contribution of genetic and epigenetic events in controlling microRNA genes and cancer phenotype. Second it will define synthetic lethal interaction between microRNA genes aberration and kinase genes in order to define novel target for therapy.Mutations and promoter methylation of microRNA genes and microRNA processing genes will be analyzed by massive parallel sequencing in a first cohort of CRC. Mathematical and in vitro analysis will be performed to test whether a mutation is a driver or passenger one. The frequency of driver mutations and promoter methylation will be confirmed in a large case-control study encompassing 2500 CRC patients. Mutational and methylation status will be matched with clinical-pathological features in order to detect correlations with clinical outcome. In order to translate my findings into drug development, genetic aberration in microRNA genes will be reproduced in CRC cell lines. Isogenic cell lines harboring the wild type or the mutant allele will be tested for cell viability in a parallel RNAi screening using siRNA libraries targeting kinase. Protein kinases are important mediators of microRNA function. More importantly, catalytic inhibitors of kinase can be easily developed making them attractive targets for synthetic lethality screening and drug development.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The neuroanatomical and neurochemical bases of temporal attention' (1998-2002) under Fifth Framework.

assistant: **Objectives**

Perceiving and estimating the passage of time is a fundamental cognitive process, which sub serves many other higher-order cognitive functions, including memory and motor planning? Most theories of timing incorporate the same basic elements: a timekeeper, a temporal template stored in working memory (WM), and a comparator that matches this template to the current stimulus. Attention interacts with these sub-components to influence our overall perception of time. For example, attention directed towards or away from temporal task demands prolongs or shortens the perceived duration. Also, attention itself is distributed across time. For example, directing attention to specific moments in time speeds responding to expected stimuli. I propose to use functional magnetic resonance imaging (fMRI) to compare the neuroanatomical bases of these two distinct aspects of temporal attention. Furthermore, event-related fMRI will be used to dissociate regions linked to attentional aspects of timing from those linked to other components, such as timekeeping or WM. Finally, task-specific changes in brain activity during the presence or absence of neuromodulatory drugs (specifically dopaminergic and cholinergic antagonists) will define the anatomical substrates of the neurochemical modulation of time estimation. Identifying the functional, anatomical and neurochemical mechanisms of temporal attention will not only provide a greater theoretical understanding of timing, but may pave the way for clinical research into the link between cognitive and motor timing dysfunction in Parkinson's disease.