RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Towards Femtosecond Electron Diffraction of Proteins' (ProteinFED) under Seventh Framework.

assistant: **Objectives**

Proteins are highly dynamic machines, perfectly engineered by nature to fulfil their dedicated function like e.g. catalysis of chemical reactions or signalling processes. Crystallography and ultrafast spectroscopy techniques gave fundamental insights to develop a time-resolved picture of biological function. However experimental tools to study ultrafast protein dynamics with atomic and ultrafast time resolution in the same experiment to fully access and describe the structure-function correlation of biochemical processes  have been lacking so far. The ambitious goal of the proposed project is to explore sample preparation strategies for the test systems Bacteriorhodopsin and Myoglobin/Hemoglobin to extend the new technology ""Femtosecond electron diffraction"" (FED) to studies of proteins. FED is a method complementary to ultrafast studies using new X-ray free electron laser sources. The main challenge for this study is sufficient sample preparation and development. For this  the group of Oliver P. Ernst at University of Toronto, a world-known structural biologist specialized in rhodopsin research, acts as outgoing host. In the group of R. J. Dwayne Miller, acting as host, at Max-Planck-Institute for Structure and Dynamics of Matter, Hamburg, the femtosecond electron diffraction experiments will be carried out, grounded on their expertise as the world-leading group in developing ultrabright electron sources on par with the European XFEL and inventors of the FED technology. The researcher Henrike M. Müller-Werkmeister is the perfect candidate for this extremely interdisciplinary project, as biochemist by training and experienced  in measurements of ultrafast biomolecular dynamics using multidimensional laser spectroscopy.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'International Organisations and the Rise of a Global Metrological Field' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The production of global metrics by International Organisations has not only penetrated the transnational social and policy fields; it has also become an integral mode of the ways International Organisations interconnect. Through their collaborative practices of quantification and commensuration, International Organisations are both constituting new realities and being reconstituted themselves. Thus, the dominance of global measurement regimes has profound implications for the ways International Organisations interact, and for the environments these new interrelationships come to generate. How is one to make sense of this emerging reality? The embryonic –but rapidly deepening– alliances between International Organisations to find global solutions to global crises, is an opportune moment for a two-fold enquiry: a. an in-depth investigation of the labour of the joint production of metrics; and b. an examination of the ways this labour reconfigures interdependencies between International Organisations and hence the field of transnational governance itself. This is a novel, problem-driven perspective that goes beyond the role and impact of International Organisations through ‘governing by numbers’: instead, we bring together multiple bodies of knowledge in order to cast light on the role metrics play in re-shaping the data collectors themselves.Hence, focusing on the policy areas of Education and Development, this is an interdisciplinary study of the ways International Organisations co-exist, compete and survive in an increasingly quantified yet uncertain world.   Building on International Relations theory, Science and Technology Studies, and using theoretical perspectives from Organisational Sociology, as well as the newly emerging field of the social studies of metrics, t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Soft Collaborative Intelligent Systems', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Soft-computing techniques have been successfully applied to analyze complex systems operating in uncertain and unstructured environments. Their ability to develop implicit and explicit models of system behaviour combined with capabilities to represent the state of knowledge of interacting computational entities, has led to a number of approaches that apply these techniques to develop multiagent systems. The European Centre for Soft Computing (Mieres, Spain) and Dr. Enrique H. Ruspini, an expert in the field of soft computing from SRI International (Palo Alto, California, U.S.) are proposing a research project focusing in collaborative information systems involving multiple interacting agents. Dr. Ruspini will investigate new research lines aimed at designing, understanding, and implementing this type of systems. The objectives of these studies will be, on one hand, robotic and sensor systems incorporating a large number of interacting agents and, on the other, distributed information systems incorporating sophisticated coordination and interaction tools. Soft-computing techniques will be applied to the design, analysis, and implementation of multiagent systems including hybrid systems where several human and autonomous agents collect, exchange, and process information to regulate system behaviour. Multiple agent systems are ubiquitous in science, industry, and commerce. The project plans to cover a wide range of applications such as manufacturing, scheduling, control, diagnosis, logistics, environmental emergency management, energy managing, and road traffic management. The project is based in a multidisciplinary approach that will integrate developments stemming from insights from a number of perspectives, notably biology, cognitive science, linguistics, economics, and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Regulation of adult neural stem cell quiescence and proliferation' to be submitted under Sixth Framework.

assistant: **Abstract**

According to WHO estimates, more than 20% of the European population will be aged 60 and above in 2020. The increase in age-associated neurological diseases such as Alzheimer's disease, Parkinson's disease and stroke will creates growing health-economic problems for European society and will have a major impact on the quality-of-life of the individual. Current treatment options for neurological diseases are limited and fail to lead to functional recovery. Adult neural stem cells (NSCs) hold great promise for restorative therapy because of their privileged location within the central nervous system and their potential to generate new functional brain cells including neurons.  The recruitment of NSCs for repair poses multiple challenges. In the adult brain, NSCs are largely quiescent and divide only infrequently. Although their proliferation increases in e.g. injury or stroke, the number of newly generated cells appears to be insufficient to compensate for the cell loss. A better understanding of the regulation of NSC quiescence and proliferation is necessary for the development of therapeutic strategies that aim at the mobilization of NSCs for repair. In the adult hippocampus, quiescent NSCs are constantly recruited into proliferation to generate new neurons.  In the proposed project we will exploit this model system to characterize the molecular control of NSC quiescence and proliferation. Our preliminary data has identified PI3-kinase signalling as a candidate pathway in this process. Using a combinatio n of molecular and cell biology, genetics, and pharmacology, we will examine the role of PI3-kinase signalling in the control of the proliferate activity of NSCs.  In addition, we will use transcriptome and proteome analysis to identify downstream targets of PI3-kinase
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'A Continent Disarmed?  Gun Culture, Gun Control and the Making of Western Europe (ca. 1870-1970)'.

assistant: **Objectives**

This research project is a comparative and transnational historical investigation of the lawful possession and use of small firearms by law-abiding civilians in Europe between ca. 1870 and ca. 1970. Over the course of this century-long period, Europe underwent a silent revolution, which led it from being a continent where guns were in daily use to becoming a place where weapons in civilians’ hands became associated with violence and crime. This led to the progressive establishment of gun control measures and to the cultural deglamorization and depoliticization of guns as a cornerstone of public order, social peace and, more generally, the smooth running of political systems. The overall goal of the project is to study the root causes of this shift and its impact on European history.The project provides a wide-ranging examination of the gun question. It adopts an integrated methodological approach that encompasses legislative measures, cultural representations and gun-related practices within a broad, comparative and transnational diachronic framework involving select countries in Western Europe (France, the United Kingdom, Germany, Italy, Spain and Sweden).Heuristically, the project does not equate the possession and use of guns with political violence and warfare; instead, it focuses on lawful gun ownership and use. This constitutes a privileged point of view and a fundamental benchmark to fully grasp the impact and cultural roots of political violence. The project has the ambition to write the first political, social and cultural history of the gun question in Europe. It will not only fill a major gap in the current literature, but also newly address the relationship between processes of enlargement of states’ competences, the control of violence and the rights of ind
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Telomeres and radiosensitivity of individuals' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

Risk estimate of radiation-induced cancer in human population is based on epidemiological data. Most extrapolations are limited by the lack of understanding of the mechanisms responsible for radiation carcinogenesis. The acquisition of knowledge on common genetic factors that might determine inter-individual differences in low dose cancer risk encounters similar limitations. During TELORAD Project, evidence is accumulating that telomeres may be involved in cellular and organismal responsesto IR. Mice lacking functional telomerase are radiosensitive. Ataxia telangiectasia, Fanconia patients are radiosensitive and show altered telomere maintenance. The major aim of TELOSENS consortiumis to work on a goal oriented project to be able to give a precise answer to the following question :ISTELOMERE HETEROGENEITY A PARAMETER OF INDIVIDUAL RADIOSENSITIVITY for short term effect?
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Single-shot dispersion-scan device for the characterization of ultrashort laser pulses' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The idea to be taken to proof of concept is a novel real-time characterization device for short laser pulses, based upon SIngle-Shot dispersion SCAN (SISCAN). The use of femtosecond laser pulses with duration from the single-cycle to the multi-cycle regime, in various applications in research, industry or medicine demands a precise characterization and control of each laser pulse. We propose a device for measuring the intensity and the phase of laser pulses, based upon dispersion scans, i.e. scans of the second harmonic spectrum as a function of dispersion of the fundamental field. The device is able to characterize individual laser pulses and therefore will provide useful realtime feedback to adjustments of any laser system. Recently, in the effort to improve the control of light pulses required for our ERC-supported research, two variants of a single-shot d-scan, i.e. one for few-cycle pulses (3-10 fs) and one for longer pulses (15-100 fs) were developed. At the same time, we introduced a new algorithm, drastically reducing the retrieval time. The combination of these developments will allow for measuring individual pulse properties in real-time for very diverse types of lasers.  At the time this application is being sent, two patent applications have been submitted.Through technical verification (Lund University, Sweden) and business activities (a small company located in Portugal, Sphere Ultrafast Photonics, already commercializing the original, multiple shot version of the device), we will demonstrate the functionality of the concept, the risks will be assessed and minimized and we will prepare to exploit the increased commercial potential, addressing laser manufacturers as well as laser users in both the scientific and commercial spheres.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'A topological approach to electron correlation in density-functional theories' (2014-2020).

assistant: **Innovation**

Density-functional theory (DFT) is the most widely used method to study the electronic structure of complex molecules, solids, and materials. Its use across chemistry, solid-state physics and materials science is a testament to its black-box nature and low cost. However, many important areas remain inaccessible to DFT simulations, including applications to strongly correlated materials and systems in electromagnetic fields. The topDFT project will deliver new conceptual approaches to design the next generation of density-functional methods. This will be achieved by pursuing three parallel strategies: i) Developing new strategies for the design of functionals ii) Implementing topological DFT, a new computational framework iii) Developing extended density-functional theories. A new approach to the exchange–correlation problem, based on a perspective from the kinetic energy of the electrons, will be developed – leading to new practical density-functional approximations (DFAs). A new framework for computation will be developed by combining techniques from topological electronic structure methods with DFT, allowing for the identification of correlation ‘hotspots’. This idea is chemically intuitive; electrons close together interact in a fundamentally different way to those far apart. Recognising these hotspots, and adapting dynamically to them, will lead to new DFAs with substantially greater accuracy. Extended-DFTs will open the way to study strongly correlated systems (e.g. high-Tc superconductors, transition metal oxides, Mott insulators) of importance in chemistry and materials science and magnetic systems (e.g. molecular magnets, spin glasses, spin frustrated systems) of importance in nano-science, advanced materials and spintronics applications. The topDFT project will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Rural Environmental Monitoring via ultra wide-ARea networKs And distriButed federated Learning' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Internet of Things (IoT) technology combined with complementary support for data analytics is the corner stone of today's digital transformation. The societal and economic impact of IoT/ML systems in urban and suburban areas significantly outpaces the one in rural areas due to a limited reach of connectivity infrastructure. To reverse further widening of the urban-rural gap, we need to bring efficient and affordable IoT/ML solutions to deep rural areas, reaching out to applications and use cases ranging from wildlife management, rural tourism, livestock monitoring, water and air pollution control, and others. By identifying main gaps in connectivity and affordable data analytics and through interleaved research, development and validation in a real-world setting, REMARKABLE will address the challenge of bringing IoT and data analytics systems a step closer to seamless, energy efficient and secure deployment in rural ares. The consortium composed of six European academic partners, five companies and five associated partners representing leading academic groups from Africa, will focus on research, development, innovation and demonstration across five use cases with six demonstration sites located in rural areas across the European and African continent. The inter-disciplinary nature of the programme provides a unique opportunity for investigation of smart sensing, IoT and data science technology from non-traditional, holistic perspectives leading to new scientific achievements and innovations. Project outputs like smart IoT sensors and devices, rural IoT digital twining platforms, ultra wide-area IoT networks, novel data analytics models and architectures will find their routes to the market via active industrial partners. The project will impact EU workforce market via n
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Quantum size effects in metallic clusters and multivalent molecularmaterials' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Research objectives and content The main objective of this project is to perform a detailed study of the quantum size effects which appear when the physical size of a metallic cluster (containing from a few atoms up to a few thousands) becomes comparable to the wavelength of an electron at the Fermi level. At very low temperatures (<1 K), the magnetic response and the specific heat of clusters becomes markedly different to the 'bulk' metallic behaviour. We intend to study this new type of magnetism in different samples in the presence of an applied field by means of several experimental techniques. The multivalent metal cluster molecules have lower nuclearity, which allows us to calculate complete spin-density mappings. Therefore, we will be able to distinguish whether the magnetic moments are or not delocalised over the molecule. Finally, we will measure the magnetic relaxation of some metallic clusters which are very good candidates to show magnetic quantum tunnelling.I Training content (objective, benefit and expected impact) The applicant will get into contact with the new, rapidly expanding field of cluster science. Besides getting a deep education in experimental physics at very low temperature, he will benefit from the interdisciplinary character of this project: chemistry and physics, experiment and theory. Links with industry / industrial relevance (22)