RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Adaptation and validation of an efficient navier-stokes solution method to turbomachinery flows, using structured and unstructured grids' in the context of a Fourth Framework call.

assistant: **Objectives**

A 3-D Navier-Stokes code was developed and validated during the period of the two years Human Capital fellowship spent by the applicant at the Technical University of Aachen (RWTH). The return TMR grant proposal should allow the transfer of the expe- rience gained by the candidate during his stays in Germany and previously in France. The research work will be carried out at the Laboratory of Thermal Turbomachines at NTUA which has a long time experience in CFD, especially as it applies in turbomachinery flows. The code will be adapted to such flows. Special attention will be devoted to model properly the tip clearance region and the phenomena associated with it. In a first stage a multi-domain structured grids approach will be developed and validated on a number of test cases. In a second stage the research work will construct the basis for a code dedicated to 3-D turbomachinery flows based on the unstructured grids approach. The algorithms will use the same numerical scheme and turbulence models as the ones used in the parent code. The entire work will also benefit from the recently acquired computational infrastructure of NTUA to promote code efficiency and parallelization.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'InTERNATIONAL TIME (IT) PROGRAMME (TO OPEN ACCESS FOR EUROPEAN ASTRONOMERS TO OTHER COUNTRIES' TELESCOPES AT THE EUROPEAN NORTHERN OBSERVATORY (ENO)' (IT).

assistant: **Innovation**

The pool of international telescopes in the Canary Islands, which effectively constitutes the European Northern Observatory (ENO), offers European Astronomers, through the international Time Programme, access to other countries' telescopes installed at ENO. The exceptional astronomical quality of the Canarian sky has attracted to the Observatories of the Instituto de Astrofisica de Canarias (IAC) the most complete set of telescopes and astrophysical experiments ever installed in European territory. This complex constitutes the Large-Scale European Facility for astronomy in the Northern Hemisphere. With the support of the Training and Mobility of Researchers Programme, it will be possible to strengthen and extend its use, in direct application of the TMR programme's goals. The present proposal for International Time (IT) is based on two different procedures for the use of 30% of the observing time of the Large-scale Facility: - Individual access (IA) by researchers to other countries' telescopes; - Access to the Collaborative Programme (CP). The IT Programme provides an excellent training-ground for young astronomers within a stable and fruitful environment of interchange. This exceptional programme places European Astrophysics at the front of competitiveness.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Ehdg' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

The EU network EAGER (European algebraic geometry research training network) will run a EuroConference on higher dimensional complex geometry as the climax of the Cambridge Isaac Newton Institute's 2002 program on algebraic 3-folds. Algebraic geometry is the study of geometric locuses defined by polynomial equations; whereas the one dimensional case (algebraic curves or Riemann surfaces) was well studied in the 19th century, and the two dimensional case (algebraic surfaces) from around 1900, the theory of algebraic 3-folds involves many subtleties, and it is only in the last 25 years that a theory has taken shape.Mori theory offers rewarding new insights into classical results on algebraic surfaces and is essential in advances such as mirror symmetry and the McKay correspondence. The Mori category consists of varieties with mild singularities; this leads to a remarkable wealth of problems that can be treated by explicitly calculations, for example, hundreds of families of Fano 3-folds. The 3 main scientific topics of the conference are:1) Mori theory and the birational geometry of 3-folds, 2) the McKay correspondence for resolutions of orbifolds, 3) Calabi-Yau 3-folds and mirror symmetry.The conference sets itself the task of making available to European algebraic geometers the new ideas and methods arising in each of these topics and exploiting their many applications to other areas of geometry and physics.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Uncovering the Mechanisms of Epigenetic Reprogramming of Pluripotent and Somatic Cell States', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The generation of animals by nuclear transfer demonstrated that the epigenetic state of somatic cells could be reset to an embryonic state, capable of directing the development of a new organism. The nuclear cloning technology is of interest for transplantation medicine, but any application is hampered by the inefficiency and ethical problems. A breakthrough solving these issues has been the in vitro derivation of reprogrammed Induced Pluripotent Stem “iPS” cells by the ectopic expression of defined transcription factors in somatic cells. iPS cells recapitulate all defining features of embryo-derived pluripotent stem cells, including the ability to differentiate into all somatic cell types. Further, recent publications have demonstrated the ability to directly trans-differentiate somatic cell types by ectopic expression of lineage specification factors. Thus, it is becoming increasingly clear that an ultimate goal in the stem cell field is to enable scientists to have the power to safely manipulate somatic cells by “reprogramming” their behavior at will. However, to frame this challenge, we must understand the basic mechanisms underlying the generation of reprogrammed cells in parallel to designing strategies for their medical application and their use in human disease specific research. In this ERC Starting Grant proposal, I describe comprehensive lines of experimentation that I plan to conduct in my new lab scheduled to open in April 2011 at the Weizmann Institute of Science. We will utilize exacting transgenic mammalian models and high throughput sequencing and genomic screening tools for in depth characterization of the molecular “rules” of rewiring the epigenome of somatic and pluripotent cell states. The proposed research endeavors will not only contribute to the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Computer-assisted drug discovery and biophysical characterisation of mutant re-activators of the transcription factor p53 as putative tumour therapeutics' (2002-2006) targeting Sixth Framework.

assistant: **Abstract**

Human cancer is still one of the most challenging areas for drug development. However, as the transcription factor p53 plays a pivotal role in intrinsic tumour suppression, the concept of rescuing mutant p53 by small organic molecules has an enormous potential for the treatment of human cancer.p53 is expressed and activated as a response to stress factors (DNA damage, hypoxia,...) and transactivates a wide variety of genes responsible for apoptosis, cell cycle arrest, DNA repair and antiangiogenesis.About 50% of human cancers lose p53 function as a result of mutations, which predominantly occur in the core DNA-binding domain. Some previous studies have gathered evidence that p53 is in fact a druggable target. However, unfocused screening approaches can be time consuming and cost intensive, and may lead to equivocal interpretations about the mechanism of action.Thus, computer-aided structure-based ligand design and ligand- and structure-based virtual screening methods shall be used to precede and iteratively complement a broad variety of established biophysical methods. To the best of our knowledge this is the first multidisciplinary approach that tries to combine computational and biophysical methods in the drug discovery process for p53 mutant reactivators.The primary objective is to identify lead structures for the interaction with suitable p53 substructures, which can be exploited for lead optimization in focused libraries. Characterization of protein-ligand interactions with biophysical methods (NMR, Xray) will facilitate the design process and allow for detailed investigations of the rescuing mechanism.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Eco efficient treatment of elv with emphasis on plastics', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Discarded End-of-Life Vehicles (ELVs) will grow from 7 million per annum today to about 10 million by 2015. Although metal recovery is standard practice, the remaining fraction - today about 2 million tons of Automotive Shredder Residues is still disposed of in landfills. All players recognize it cannot be a long term sustainable solution. The industry at large, has agreed that over the next twenty years, most of these tonnage should be recovered.In the European Union, the ELV treatment industry is an important economic activity, involvingclose to 20000 collectors / dismantlers - mostly SMEs - as well as a few hundred companies operating heavy duty shredders. The need for improved environmental protection from ELV treatment, and for higher material recovery requires drastic changes in operational practices, as well as new technologies.Over the last few years, considerable work has been conducted in this respect, by some segments of the industry, in several Members States. However it has taken place in an uncoordinated manner. The objectives of the project is to set up a Thematic Network aiming at: *creating the conditions of synergy and cross interaction in Europe, *becoming a credible European information reference source, helping achieve deeper understanding in order to facilitate the necessary changes, through the chain". *Iaunching those 'obvious' projects, made possible by the critical mass and diversity of participants in the network, and to be funded / run independently of this Thematic Network project.The expected output will be: . an in-depth, validated, inventory of national and regional projects and activities, of global technologies, of available European infrastructures and resources, . an assessment and synthesis, accepted at large, and leading to: * full
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Eurotalents: a European programme for transnational mobility of experimented researchers managed by CEA' (EUROTALENTS), addressing dissemination and exploitation.

assistant: **Impact**

CEA is convinced that the ability of research institutes to offer attractive working conditions and career opportunities to researchers is a key factor in meeting the challenge of maintaining and boosting Europe’s scientific and economic competitiveness. Thus, thanks to the European Commission cofunding, CEA would like to develop a centralised programme dedicated to researchers’ transnational mobility and based on open merit competition and international peer review.  This programme called ‘Eurotalents programme’ will aim at increasing the mobility of scientists and at offering a boost in their career thanks to the access to new research capacities. Eurotalents will open world class laboratories within CEA and abroad to researchers having an excellent scientific experience and wanting to broader their career via a research project in the scientific topic(s) of their choice within CEA well-known domains of expertise: (i) Energy, environment and climate change, (ii) Life sciences and biotechnology, (iii) Nanosciences and nanotechnologies, (iv) Science and technology of high performance computing, (v) High energy physics and physics of the universe. Eurotalents will thus offer fellowships to foreign researchers wanting to work in CEA (Incoming fellowships) or to French scientists aiming at developing their scientific career abroad (Outgoing fellowships). The selected researchers will also benefit from CEA network all over the world and have access to training courses in scientific and non scientific disciplines.  Eurotalents will be directly operated by CEA that has already proved its capacity to efficiently manage European projects and national programmes according to strict rules   Eurotalents will exploit synergies between UE actions, CEA research facilities and scienti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'A EUROpean training and research network for environmental FLOW management in river basins' in the context of a Horizon 2020 call.

assistant: **Objectives**

A EUROpean training and research network for environmental FLOW management in river basinsThe regulation of river flows is one of the biggest stressors affecting river ecosystems across the world. In manywesternised countries, major legislative efforts are therefore underpinning the development of new approaches to mitigatethe impacts of river flow regulation (e.g. EU WFD, US Clean Water Act, South Africa National Water Act, Australian WaterResources Act). These approaches are based on optimising the management of river flows to maintain services to humans(e.g. water supply, hydropower) whilst protecting and/or rejuvenating the aquatic environment with water of adequatequantity and quality in space and time (i.e. environmental flows, aka e-flows). In this context, a field of applied aquaticscience has developed to generate the evidence base for identifying the best ways to manage the quantity, quality andpatterns of e-flows to sustain river ecosystems. EUROFLOW will train a new cohort of researchers to be future leaders inthis field.


**Keywords:** Reservoir, flood, low flow, river, abstraction, water quality, freshwater biology
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Research on tribology within xerographical processes' to be submitted under Fifth Framework.

assistant: **Abstract**

The sustainability and quality of xerographical processes depends on tribological influences. The research aims at modeling, analyzing and validating these tribological aspects in relation to the material and mechanic engineering of xerographical components and their remaining life expectancy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Driving Rural Innovation through startup Villages across Europe' (DRIVE), addressing dissemination and exploitation.

assistant: **Impact**

In the EU the bio-based economy drives growth through job creation and innovation by utilizing renewable resources and through alignment with the Circular Economy and bioeconomy. In order to stay competitive, Europe´s industry must become greener, circular and digital through collaboration among companies, Member States, and rural regions in Europe.Within this context, the general objective of DRIVE is to increase the implementation of European local startups, fostering innovative ecosystems for the development of new value-added products, technologies and approaches, via a series of exploitation and trainings actions. Thus, the three pillars of the project, namely: the identification of the needs and project´s users, for instance, at least 2 regional accelerators and incubators will be contacted by the consortium in each of the three roadshows, according to the methodology, to exchange best practices and reinforce SMEs and start-ups participation, the second pillar, the roadshows and the hackathons, and the last one, the mentoring for the development of the technologies, are closely intertwined, as they have been conceived to cooperate in an integrated way, in order to exploit the benefits gained by the work team, meaning boosting the quality of their work and possible results. Therefore, the main outcomes of DRIVE can be summarized in four: to develop a tailored business model at an European level for pitching to investors, to apply for regional initiatives or European financial support instruments, to prepare a pitch presentation and identify investor events and to enroll in further acceleration programs for continued idea deployment and commercialization.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Strong gravitational lensing from galaxy clusters: a tool for cosmology' (ARTISTICS).

assistant: **Concept**

The statistical properties of gravitational arcs in galaxy clusters is sensitive to several factors which depend on cosmology, like the geometry of the Universe, the number of clusters at redshifts where they are most efficient for lensing and the internal structure of lenses. Arc statistics therefore offers a potentially powerful cosmological tool. However, several studies have been done so far, attempting to constrain cosmological parameters using the statistical properties of lensed arcs but their result s turned out to be in contrast with what suggested by many other cosmological tests, evidencing a profound lack in our understanding of the physical properties and evolution of galaxy clusters which determine their lensing properties. The goal of this proj ect is close this gap by combining a large amount of observational data with detailed theoretical modeling. On the one hand, we will test suitable software for automatic arc-detection and classification, and we will use them for analyzing the data from the Sloan Digital Sky Survey. We will update and extend existing observations and we will develop tools for data analysis which will be usable for manipulating both simulated and real images. On the other hand, we will use numerical simulations for studying the lensing properties of realistic cluster models in different cosmological frameworks. We will investigate the lensing effects by galaxy clusters obtained from high-resolution N-body and (magneto-) hydrodynamical simulations. We will evaluate the impact on arc statistics of dynamical processes arising in clusters, like mergers. We will use large cosmological volumes for studying projection effects due to the alignment of matter along the line of sight and we will try to understand which role is played by magneti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Electrical Systems Compatibility for Advanced Railway Vehicles' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Objectives and content Promotion of environment friendly, reliable and safe rail transport of passengers and goods within and across national borders is a major EU objective In order to reach this goal, interoperability between all subsystems of a rail network is a prerequisite. Numerous technical barriers, such as different track widths, supply voltages, or signalling systems have long been identified. A fourth barrier, the electrical compatibility of new vehicles with the existing power supply, signalling and vehicles, has more recently been found to be a major obstacle: large regional transportation networks collapsed, electric vehicle interaction caused protective shutdowns and delays, signalling systems and barrier crossings malfunctioned, information and telecommunication systems have been disturbed, and TV/computer screens always flicker, all due to a lack of electrical compatibility and interoperability of components in an electrical rail network. These effects have led to costly reworks and delays for the manufacturing industry and to deteriorated quality of service and capable utilisation for the railway operators. The objective of this project is to overcome these problems by jointly tackling its most important aspects in a multi-national and cross-company project team, comprising several participating companies from the system and component supplier side, the railway operators, and from academic and industrial research. An important goal of the project is to establish an open modelling framework and adequate subsystem models for the complete transportation system, enabling us, as a second goal, to reliably predict and avoid interoperability problems before putting a system into operation. This will, as a third goal, had us to a design process and a set of de