RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'An RNA aptamer-based tool  for the detection  of pathological protein aggregates in biofluids' under Horizon Europe.

assistant: **Concept**

The AptALS project aims to develop a highly sensitive and scalable RNA aptamer-based kit for detecting TDP-43 aggregates, a key biomarker in ALS. The kit consists of 3 main components: (i) biotinylated RNA aptamers that selectively bind aggregated TDP-43, (ii) a detection system (fluorescence or chemiluminescence) to quantify binding events, and (iii) a modular assay format compatible with ELISA-like workflows, allowing seamless integration into clinical laboratories. By leveraging our patented aptamers, we will validate their performance in a standardized detection assay, ensuring clinical robustness. Unlike conventional antibody-based methods, RNA aptamers offer superior specificity and adaptability, enabling non-invasive, early-stage ALS detection. This innovation fills a critical gap in ALS diagnostics, replacing invasive lumbar punctures and costly neuroimaging with a cost-effective, scalable alternative. The AptALS project will focus on three key objectives: (i) assay validation, (ii) optimization of detection methods (fluorescence vs. chemiluminescence), and (iii) benchmarking with ALS patient samples. The project is led by a multidisciplinary team with expertise in biophysics, molecular biology, and computational modeling, supported by IIT’s state-of-the-art genomics, proteomics, and microscopy facilities to ensure technical rigor and scalability. Beyond its scientific impact, AptALS delivers significant societal and economic benefits. Early ALS detection can enable timely intervention, improve patient care, and reduce healthcare costs. The diagnostic kit is designed for B2B distribution, targeting hospitals, diagnostic laboratories, and pharmaceutical companies for clinical trials and patient stratification. Positioned at the forefront of neurodegenerative dise
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'High precision multi-jet dynamics at the LHC' (JetDynamics) targeting Horizon 2020.

assistant: **Abstract**

Precision tests at high energy colliders are an essential tool for gaining insightinto the nature of the Standard Model of particle physics and the fundamental interactions. The data currently being obtained by the LHC experiments will allow a large number of observables to be measured at a percent level accuracy. This data has the potential to probe deeper into the flaws of the Standard Model. However, the complexity of theoretical predictions using perturbative quantum field theory currently prevents many of these precision tests.JetDynamics aims for a breakthrough in precision predictions for the measurements of Standard Model interactions through the study of the dynamics of multiple strongly interacting hadronic jets. Percent level predictions for 2 to 3 scattering processes involving the Higgs boson and electroweak vector bosons will allow a unique insight into fundamental properties of the Standard Model in the new high energy region probed by the LHC.In order to achieve this goal a complete set of quantum corrections at next-to-next-to-leading order (NNLO) in perturbation theory are required. JetDynamics bridges the gap between mathematics physics and experimental collider physics and will develop a new generation of computational tools and methods} that will overcome current bottlenecks. The work program attacks this problem on three fronts:A) Develop revolutionary new ideas from the study of on-shell scattering amplitudes to address the current bottlenecks in the computation of multi-leg two loop amplitudes in QCD.B) Develop highly efficient tools for NNLO predictions with multi-jet final states and perform precision phenomenological studies of jet dynamics at the LHC.C) Lay groundwork for jet production beyond NNLO and build towards 1% perturbative accuracy.J
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Patents, Bioethics and the Human Body:  Reconceptualising Bioethics in Patent Decision-Making and the Governance Function of Patents' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

PatentsInHumans challenges the current marginalisation of bioethics in patent decision-making for technologies related to the human body. A patent gives a rightsholder the right to stop others using a patented technology. This allows them to control how that technology is provided, to whom, and on what terms. Where patents are for technologies related to the body, this control poses considerable bioethical issues because patents can affect how we treat, use and modify bodies. Yet patent systems generally do not engage with such implications. All patents are treated the same, regardless of the underlying technology i.e. a patent on an engine part is treated the same as a patent on a medicine, despite the significant effects the latter has for health. PatentsInHumans proposes that there is a self-reinforcing cycle where patents are granted even if bioethical implications are posed by patents over such technologies; that there are limited incentives for rightsholders to license patents in a way that addresses bioethical implications, and that patents, once granted, are difficult to challenge if bioethical issues arise. PatentsInHumans radically reconceptualises patents as governance devices over the body in such contexts. It proposes that when patents are applied for, the underlying technology’s relationship to the body must be considered. The project will therefore evaluate the bioethical implications that patents over such technologies have for how we treat, use, or modify our bodies. These implications must guide patent decision-making and the adoption of licensing or grant conditions that pre-empt bioethical issues. The project develops a cross disciplinary institutional analysis to evaluate key legal, structural and cultural barriers leading to the marginalisation of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'CITY NETwork for fair MOBILity' (CITYNETMOBIL), addressing dissemination and exploitation.

assistant: **Impact**

CityNetMobil focus is on automated transport systems and its approach, is to organise dissemination actions to raise the awareness around these systems. Awareness to increase acceptance, by politicians, local mobility planners and general public, of automated transport systems as a more inclusive urban transport solution, providing better access to all, environmentally friendly, capable of reducing urban transport share of energy consumption and CO2 emission, and safer than conventional transport modes. Seventh in a stream of projects, CityNetMobil, will diffuse the results obtained by all its predecessors, coordinate the activities of a group of cities interested in these kind of systems and willing to host events to make people acquainted with such technology, and network toward other cities to introduce automated transport systems to them. The latest of the six predecessor projects, CityMobil, had first the idea of creating a “reference group” of cities with the aim of receiving suggestions on mobility problems which could be addressed with advanced transport systems. Such reference group however proved to be more than just a “prompter” of mobility problems; soon cities asked for some kind of action by the project side to promote advanced transport systems there. CityNetMobil will start from such reference group, re-invite the member cities and any other who would join, to a selection process and then organise events in five selected cities. CityNetMobil will prepare common dissemination material to inform and invite people to the events and to greet people there (e.g. audiovisual material, posters and gadgets). Each CityNetMobil event will feature the installation of a small showcase of moving automated vehicles, a conference and an exhibition with audiovisuals and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Two-dimensional high entropy alloys and ceramics' in the context of a Horizon Europe call.

assistant: **Objectives**

“Entropy engineering” recently had exceptional impact on bulk materials science by invention of bul“Entropy engineering” recently had exceptional impact on bulk materials science by invention of bulk high entropy alloys and ceramics. The underlying idea is that by equiatomically adding ≥5 principal elements to alloys/compounds, the much increased configurational entropy stabilizes otherwise non-accessible single “high entropy” phases with an unique random elemental occupancy on a crystalline lattice and hence novel functional properties. Likewise, reducing dimensionality in “two-dimensional” (2D) materials recently had exceptional impact on materials science due to the 2D materials’ unique functional properties. Despite these exciting individual prospects of “entropy engineering” and “2D materials”, combination of these two concepts to synergetically create novel 2D high entropy materials (2D HEMs) as  a novel materials class with novel functional properties with possible applications in electronics and catalysis remains lacking. In “HighEntropy2d” we will fabricate unprecedented 2D HEMs (2D high entropy alloys, oxides and sulfides) using for the first time scalable vapour deposition and a 2D template/2D confinement approach for both 2D film and 2D nanoflake form, asses their novel properties and perform first tests of their applicability for electronic devices and catalysis. Reducing HEM dimensionality to 2D will also create a unique opportunity to for the first time study in situ and at the atomic scale currently unknown fundamental diffusion, crystallisation, phase transition and separation mechanisms in HEMs (using a globally unique (scanning) transmission electron microscopy ((S)TEM) setup), to obtain fundamental insights relevant to HEMs even beyond the here newly
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Pre-Commercial Procurement of Innovative Triage Management Systems Strengthening Resilience and Interoperability of Emergency Medical Services' to be submitted under Horizon 2020.

assistant: **Abstract**

Emergency Medical Services (EMS) in Europe are characterised by a heterogeneous landscape with diverse organisational setups, technology standards, coordination mechanisms and actors. This is the result of different historical and institutional contexts. However, these EMS are united by the common aim of providing timely care to victims of sudden and life-threatening emergencies or disasters in cross-border settings and international humanitarian missions. Fostering the response capacities and increasing the cooperation of the Emergency Medical Services Systems (EMSS) is of decisive importance for strengthening the resilience of European societies.During the prior iProcureSecurity project, a large number of EMS were involved to identify, evaluate and prioritise future challenges and needs. The creation of an interoperable, flexible triage management system supported by modern technologies was among the most requested solutions in the context of security-related scenarios.This iProcureSecurity PCP action is a result of those intense participatory consultation processes. The action will lead to an innovative triage management system that provides a) quick and accurate overview of victims and their status; b) decision support for better allocation of available resources and quicker support for patients; c) improved interoperability with other first responders and relevant actors; d) reduced handover times between ambulance transport and hospitals; and e) insights for quality assurance and training measures.Following the EC Guidelines on Pre-Commercial Procurement (PCP), through a competitive series of design, prototype and pilot steps, the iProcureSecurity PCP will contract suppliers to deliver the creation and deployment of the envisaged triage management system.Besides t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The management of agrarian areas from Protohistory to modern times: modeling time-space dynamics from archaeological sources, written and environmental data' (MODAGSPACE).

assistant: **Concept**

The proposed research project focuses on the study of spatial and temporal dynamics of agrarian spaces in the long term (From Protohistory to the 19th century), mainly from the analysis of ceramic material collected off-site" during Fieldwalking operations, coupled with various other sources (written, planimetric, ethno-archaeological, environmental). This project aims to develop research on management of agrarian space carried out during my thesis (defended December 14, 2007) and the work done under the Archaedyn program of the French ACI Spaces and Territories (2005 -2007) promoted by the French Ministry of Research on the same theme. Within these projects, contacts were made with the Institute of Anthropological and Space Studies in Ljubljana (ZRC ZASU), allowing a fruitful collaboration on this topic, which can contribute to enrich Franco-Slovenian research programs (Proteus, ModelTER). These experiences have helped to propose a protocol of restitution and modeling of spatial and temporal dynamics of agrarian spaces. Research programs have already helped the modeling of major trends affecting the agro-pastoral practices in the long term by comparing changes legible within several micro-regions considered as observation windows. The post-doctoral fellowship at Ljubljana's ZRC SAZU goals, building on these achievements, to develop and enrich this protocol analysis while extending a confrontation to information from various documentary sources (archaeological, textual or environmental), and using the host laboratory skills in the fields of GIS, remote sensing, and Lidar processing. The course will also provide an opportunity for exchanges on methods (for fieldwalking) with colleagues from Slovenia."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Real-time Adaptive Particle Therapy of Cancer' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The Real-time Adaptive Particle Therapy Of CanceR (RAPTOR) consortium comprises world-class research institutes, non-academic particle therapy (PT) centres and industrial providers of PT equipment, offering a platform for intercultural, interdisciplinary and intersectoral training of early stage researchers (ESRs) in the field of medical physics with a focus on real-time adaptive PT. This comprehensive expertise and infrastructure is required to address and solve challenges in the clinical implementation of real-time adaptive PT.PT is an advanced type of radiotherapy used to treat a constantly rising number of cancer patients. PT allows to target tumour with a high accuracy while sparing healthy surrounding tissue from dose. However, changes in anatomy or positioning and organ motion give rise to uncertainties which need to be further minimized to exploit the full benefits of PT. Adapting PT plans in real time has the potential to provide truly personalized treatments, allowing for better target control and less toxicity. A move towards wide clinical implementation of adaptive PT approaches is currently prohibited by (i) stepwise treatment workflows that are time-consuming and largely manual, (ii) the inflexibility of commercial PT equipment, and (iii) the wide range of PT equipment and protocols.RAPTOR ESRs will conduct research projects at both academic and non-academic health care facilities which will sharpen their focus on clinical needs with respect to real-time adaptive PT. The active involvement of industry ensures that the transfer of industry-relevant skills is an integral part of individual ESR projects. This will guarantee rapid translation of clinical needs into innovative and marketable solutions.RAPTOR aims to train a new generation of researchers, enabli
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Significance of external / anthropogenic nitrogen for central baltic sea n-cycling' (SIGNAL) under Fifth Framework.

assistant: **Objectives**

Problems to be solvedThe Baltic Sea ecosystem is eutrophied by inputs from the activities of 80 Million people living in its drainage area. Nitrate and ammonia, essential nutrients for plankton growth, are introduced mainly from the farmland along the rivers that drain into the Baltic Sea and via atmospheric deposition. The high nutrient concentrations are a problem for the coastal area as stated by the Helsinki Commission (HELCOM). Far-reaching effects of eutrophication like increased primary production, increased frequency of toxic phytoplankton blooms, oxygen depletion in sediments, and reduced fish stock recruitment (e.g. Baltic Cod) are problems, which demand international initiatives. The Urban Waste Water Treatment Directive" (Directive 91/271/EEC) strives for better water quality, especially when other countries could be affected by wastewater discharges. The Baltic Sea area is regarded as a particularly sensitive environment in this respect, and the need to treat wastewaters in this region more stringently is evident. The purpose to decrease the input of nitrate, in particular from agricultural sources, is also pursued by the Nitrate Directive (91/676/EEC). Since the directive has failed to be implemented by the member states, it is of utmost importance to assess the impact of the nitrate load that has been dumped during the last years. In the central Baltic Sea nutrient concentrations have been roughly doubled during the last 30 years. Although concentration measurements have been carried out intensively over the last decades in rivers and the open Baltic Sea, it is still difficult to asses the effects of riverine nutrients within the marine environment. Also the establishment of a clear relationship between riverine and atmospheric nitrogen inputs and the inc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Why farm and field size matters: Exploring their role for food security and sustainable agriculture in South America'.

assistant: **Concept**

Global agricultural systems fail to meet food security objectives, are a major cause of global environmental degradation, and are currently undergoing a rapid scale transition. This transition mainly affects small-scale farmers, who are key to attaining food security as they constitute more than 80% of all farms and disproportionately contribute to food production and nutrition. Guiding the agricultural transition onto sustainable pathways that safeguard food security is thus important. Therefore, a sound understanding of the operational realities of farms and fields with respect to size, productivity, location factors, and socio-economic and environmental impacts is needed to develop targeted actions and policies, but is currently lacking especially for large spatial scales. FFSize will address this knowledge gap based on four work packages focussing on South America. WP1 will overlay novel data sets on farm and field size to quantify and map their relationship and use advanced statistical methods to identify determinants of their spatial patterns. WP2 will assess size-related differences in agricultural land-use intensity of farms and fields based on input, output, and system metrics and map intensity archetypes. WP3 will evaluate size-related environmental and socio-economic impacts of farms and fields by linking them to metrics such as land-cover change and nutritional value. WP4 will synthesise this action by mapping socio-ecological systems states to analyse trade-offs at the food security-sustainability nexus and outline potential pathways into preferred future states. FFSize will contribute substantially to the fields of land-system, sustainability, and food security science. It will have major policy relevance for current discussions on land reform, large-scale