RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Ultra fast non invasive imaging of temperature for application in gene therapy and tumor ablation'.

assistant: **Concept**

This proposal is centered around Magnetic Resonance Imaging (MRI) Guided Focused Ultrasound (FUS) and two of its medical applications, tumor ablation and gene therapy. FUS has been known to be very effective to heat tissue locally. However, problems with the localization and dosimetry of | thermal dose have prevented widespread use. MRI temperature imaging combined with anatomical MRI can help to overcome | these problems. The research will be centered around the development of ultrafast noninvasive temperature imaging in vivo and the design effective FUS within the MR magnet. | Two possible applications will be further investigated: | I) Application of high intensity FUS to destroy a tumor without damaging surrounding tissue. 2) Temporal and spatial control of expression of a therapeutic gene, sensitized to heat using the Heat Shock Protein prom | Thus, high local and temporal control of gene therapy can be achieved using controlled periods of local heat elevation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Dynamic Radio for IP-Services in Vehicular Environments' (DRIVE) targeting Fifth Framework.

assistant: **Abstract**

The DRIVE project addresses the convergence of cellular and broadcast networks to lay the foundation for cost-efficient provision of IP-based in-vehicular multimedia services for information, education, training, and entertainment. The project approach to increase the total spectrum efficiency is to optimise the inter-working of different radio networks (GSM, GPRS, UMTS, DAB, DVB-T) in a common dynamically allocated frequency range and to enhance the co-operation between network elements and applications n an adaptive manner. The required key competence is covered by a consortium of leading telecommunication manufacturers, broadcast operators, cellular network operators, multimedia content providers, the car industry, and R&D organisations.Objectives:The citizens' expectation for cost efficient provision of existing and emerging mobile multimedia services for information, education, training, and entertainment is faced with the reality of scarce radio resources. The overall objectives of the DRiVE project are to enable spectrum-efficient high-quality wireless IP in a heterogeneous multi-radio environment to deliver in-vehicle multimedia services.To achieve these objectives the DRIVE project addresses the convergence of cellular and broadcast networksbby tackling two key issues:1. The optimised inter-working of different radio systems (GSM, GPRS, UMTS, DAB, DVB-T) in a common dynamically allocated frequency range.2. The enhanced co-operation between network elements and applications in an adaptive manner.Work description:To achieve these challenging objectives DRiVE is devided into four workpackages consisting of several tasks. Workpackage and task leaders have been appointed to ensure that the objectives will be met.WP1 (dynamic radio aspects): develops methods for dyna
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Deciphering the cyst nematode parasitic program by uncovering how their virulence is orchestrated' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Plant parasitic nematodes represent a significant group of plant pathogens that threaten current and future food security. Among them, the cyst nematodes target some of the most important crop species (tomato, potato) and cause up to 80% losses. European regulations prohibit the future use of many effective nematicides. We must improve our understanding of the virulence of the cyst nematodes to identify new targets for a sustainable biotechnological control of these pests. Here, I will use my experiences gained on plant-fungal interactions to address a major question in plant-nematode interactions: how is plant-parasitism orchestrated at the molecular level? To be virulent, cyst nematodes must inject “effector” proteins into the plant. These effectors are primarily produced in either the nematode’s dorsal or sub-ventral glands. Hundreds of these dorsal gland effectors are unified by a six base-pair non coding DNA motif, termed the “DOG box”. In a recent effort, a transcription factor that can recognize the DOG-box was identified, termed the “DOG box reader”. This discovery is the first tangible insight into the regulation of plant-nematode parasitism and opens the possibility to explore a new area of research. However, I recognize that the DOG box and its corresponding reader are only one part of the jigsaw puzzle. To complete the picture, in depth and breadth, I need to know: How does the DOG box reader work in vivo, and does it work alone? What are the genetic signatures and readers of other glands and at other times? To what extent are regulatory mechanisms conserved between cyst nematode species? I expect that successful completion of this fellowship will launch my independent academic career, drive forward the state-of the-art with a holistic “spatio-temporal” view
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Advanced Materials Research Postdoctoral Fellowship Programme', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Advanced materials science is one of the key enabling technologies identified by the European Commission as boosting European competitiveness, creating jobs, and supporting growth. ADMIRE is an innovative postdoctoral fellowship programme providing interdisciplinary and intersectoral training in strategic priority areas of advanced materials research, aligned with the strengths of AMBER: SFI Research Centre for Advanced Materials and BioEngineering Research. The aim of ADMIRE is train the next generation of research leaders in Europe in advanced materials science. A rigorous training programme will equip the fellows with the skills and flexibility to develop independent careers in their field of research in academia or industry. The ADMIRE programme will fund 12 two-year incoming fellowships in Ireland in the area of advanced materials, with fellows being recruited through 2 calls for proposals over the 60 month duration of the project. AMBER/TCD will contribute 1.19M to support the implementation of the programme, and will ensure that a fair, transparent, open and merit based recruitment process is implemented in the 2 calls. ADMIRE fellows will be based in one of the 8 academic partners of AMBER, and they will have access to the full range of AMBER state of the art facilities and expertise at these locations.  Principal investigators across the academic partners will supervise, host and train fellows. Industry partners will host fellows during secondment periods and will contribute to industry relevant training in the ADMIRE programme. Fellows will have complete freedom of choice in their supervisor, host institution and research topic, provided it aligns with the existing research priorities within AMBER. ADMIRE is an exciting new strategic endeavour which will contr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Axion Search in DarkSide-20k' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Dark matter constitutes approximately 85 % of our Milky Way galaxy. Relic axions and Weakly interacting massive particles (WIMPs) are two of the most promising candidates for dark matter. Axions were proposed to explain the invariance of the two discrete symmetries P and CP, in strong interactions while the rest of the Standard Model (SM) violates them. While relic axions were produced in abundance during the big bang, axion-like-particles are produced in stars due to Compton-like and bremsstrahlung processes. The axion-like-particles produced in Sun are called the solar axions. Because the solar axions are relativistic, they are a candidate for hot dark matter. This project aims at detecting the solar axion interaction and the diurnal and annual modulation of light dark matter particles in the silicon of the state-of-the-art Silicon Photomultipliers (SiPM) sensor array of the DarkSide-20k experiment. The proposed search would be first of its kind. This project involves training in new and advanced research techniques which will pave the way towards a successful career in astroparticle physics for the applicant and the transfer of knowledge to the host institution.


**Keywords:** Solar axions, Silicon Photomultipliers, SiPM module
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'European Regulatory Private Law' to be submitted under Seventh Framework.

assistant: **Abstract**

The focus of the socio-legal project lies in the search for a normative model which could shape a self sufficient European private legal order in its interaction with national private law systems. The project (1) aims at a new–orientation of the structures and methods of European private law based on its transformation from autonomy to functionalism in competition and regulation;(2) suggests the emergence of a self sufficient European private law, composed of three different layers (a) the sectorial substance of ERPL, (b) the general principles – provisionally termed competitive contract law – and (d) common principles of civil law; (3) elaborates on the interaction between ERPL and national private law systems around four normative models: (a) intrusion and substitution, (b) conflict and resistance, (c) hybridisation and (d) convergence; (4) analyses the new order of values, enshrined in the concept of access justice (Zugangsgerechtigkeit).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Particles of human origin extinguishing natural solar irradiance in climate systems' under Fifth Framework.

assistant: **Concept**

PHOENICS is a global modelling project to study the direct climate effect of multi-component mixed troposphere aerosols. The potentially great climatic importance of aerosols urgently requires improvement of the estimates of the climate effect of aerosols and better evaluation of the associated uncertainties. Innovative size-resolved simulations of the distribution and properties of the mixture of all major aerosol components will be performed with a global 3-dimensional atmospheric general circulation model to assess the direct effect of aerosols. Several of the main uncertainties associated with this effect will be quantified and reduced by model improvement, comparison to selected observations and optimal use of satellite data. The impact of European emissions on the European and global environment and climate, and the influence of other world regions on Europe will be assessed focusing on the role of the Mediterranean.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Reasonable Doubt: An epistemological and psychological approach' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The purpose of this research is to shed light on the nature and dynamics of doubt and confidence in complex epistemic decision-making, through a study of the notion of reasonable doubt. While doubt is considered a rational virtue, waiting until complete certainty before accepting and acting upon a given hypothesis is unreasonable in many contexts. Given some evidential support for the hypothesis, the threshold beyond which acceptance rather than doubt is the reasonable option seems to depend on the decisional context (particularly the cost of a possible error): jurors in criminal trials should thoroughly consider alternative scenarios before convicting a defendant; doctors or policy-makers, however, may have to take action upon less strongly confirmed hypotheses, depending on the relative costs and benefits of action/inaction. Such a decision-theoretic view of reasonable doubt relies on the assumption that the consequences of an hypothesis are exogenous to the rational evaluation of its evidential support: one first updates one’s degree of belief in view of the evidence, and then assesses whether, given the context, the hypothesis is beyond reasonable doubt (i.e. should be accepted and acted upon). But is it the case that agents’ degrees of confidence in a hypothesis, and their weighing of various pieces of evidence, are impermeable to the decisional context? Is the juror’s actual belief independent from her having to bring a consequential verdict? This research aims to study the epistemological norms of reasonable doubt, taking account of the psychological reality of the agents’ reasoning. The main objective of the fellowship is to develop an original empirical research programme, testing the effects of the consequentiality of epistemic decisions on reasoning. This int
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Nicotine, nicotinic receptors and ageing' (1998-2002).

assistant: **Innovation**

The project regroups the laboratories of M. Zola (I), D. Rubinsztein (UK), J.P. Changeup (F), K. Fuse (S), P. Inciter (D) and P. Moser (Synthelabo Recherché, F). Its aim is to explore the role of nicotinic acetylcholine receptors (nAChR) in brain ageing and related deficits. The workplan includes:1. To study,whether polymorphisms in nAChR genes influence the rate of cognitive decline in the elderly;2. To characterise the molecular mechanisms of nicotine neuroprotection and neurodegeneration caused by nAChR deficits in animal models, including the study ofa. the influence of nacho isotopes on brain ageing using nacho subunit mutant mice,b. the interaction between nacho deficits and other age-related pathogenic factors (e.g., amyloidal beta protein and tropic factors),c. the influence of nacho deficits on neuronal apoptosis, and d. the comparative genomic of ageing in humans and nacho mutant mice;3. To characterise new, nicotinic agents for the therapy of age-related neurodegeneration and cognitive deficits.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Protein Rigid Organization for Powered Engineered Locomotion' in the context of a Horizon Europe call.

assistant: **Objectives**

Proteins are nature's nano-machines, driving essential biological processes, including those involving mechanical work: DNA replication, membrane remodelling, and cargo transport. Synthetic protein motors have enormous potential in health and material applications and could help us unravel the mechanism of natural protein motors. At present, the ability to design protein motors from scratch remains beyond our reach. The PROPEL project aims to address this challenge by constructing the first genetically encodable de novo protein walkers capable of powered, directional motion along designed protein tracks. We will combine cutting-edge AI design tools with sophisticated single-molecule tracking experiments to create protein motors based on a driven Brownian ratchet mechanism. This approach represents a significant leap forward in synthetic molecular machines, surpassing the current state-of-the-art in DNA nanotechnology by leveraging the chemical versatility, genetic encodability and hyper-stability of designed proteins.Key objectives of PROPEL include designing rigid asymmetric tracks (Objective 1), creating specific anchors to control where and when tracks grow (Objective 2), integrating power sources such as alternating electric fields, enzymatic reactions, and enhanced diffusion effects (Objective 3), and demonstrating cargo transport applications such as force generation and active motion in live cells (Objective 4). PROPEL's innovation lies in its ability to create entirely de novo protein motors and tracks that expand our understanding of molecular processes and open new avenues for bionanotechnology. Potential applications range from synthetic cell machinery and precision medicine to smart materials and programmable nanorobots. By creating the first powered and dir
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Assess Inquiry in Science, Technology and Mathematics Education' (ASSIST-ME), addressing dissemination and exploitation.

assistant: **Impact**

ASSIST-ME is a high level research project with a societal impact that will investigate formative and summative assessment methods to support and to improve inquiry-based approaches in European science, technology and mathematics (STM) education. Based on an analysis of what is known about summative and formative assessment of knowledge, skills and attitudes related to key STM competences and an analysis of European educational systems, the project will design a range of combined assessment methods. These methods will be tested in primary and secondary schools in different educational cultures in Europe in order to analyse the conditions that support or undermine the uptake of formative assessment related to inquiry processes.The resulting synthesis of opportunities and restrictions for implementing an assessment culture using both formative and summative approaches will be evaluated and discussed in relevant forums in order to formulate guidelines and recommendations for policy makers, curriculum developers, teacher trainers and other stakeholders in the different European educational systems.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Photoemission Orbital Cinematography: An ultrafast wave function lab'.

assistant: **Objectives**

Directly watching in slow-motion videos how electrons move in quantum mechanical orbitals and how this motion shapes the functionalities of condensed matter has been a dream shared by all natural and life sciences. Yet, this vision comes with the daunting challenge of mapping the microscopic structure of electronic orbitals with simultaneous ultrafast time resolution. We will turn orbital cinematography into reality. This seminal breakthrough will rely on the unique synergies between photoemission orbital tomography (POT), ultrafast photoelectron spectroscopy, lightwave electronics and advanced theory, developed and pioneered by us. Secured by our recent proof-of-principle studies, we will combine these aspects to transform POT to a cinematography at unprecedented time scales, faster than a single oscillation period of light. This will allow us to systematically explore the nanocosmos on its intrinsic femto- to attosecond (the billionth part of a billionth of a second) scales. We will take actual slow-motion movies of molecular orbitals during charge transfer processes, surface chemical reactions, and wave packet motion driven by lightwaves. Orbital Cinema will thus resolve key questions related to a wide range of applications, from next-generation optoelectronics, energy conversion, photochemistry and catalysis to prospective electronics at optical clock rates. We expect it to revolutionize our understanding of the nanocosmos by elucidating–on elementary spatio-temporal scales–the inner structure of quantum leaps, strong-field control of electrons, charge transfer processes, and chemical reactions as well as their control by electric fields and light. Since the dawn of quantum mechanics, the temporal evolution of electronic orbitals has been among the most sought-after