RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Capillary systems for advanced point-of-care diagnostics' to be submitted under Horizon 2020.

assistant: **Abstract**

The worldwide in vitro diagnostic (IVD) is continually growing. At least 36% of the IVD market comprises point-of-care (POC)tests, which are performed by healthcare professional in various settings or by patients themselves. A large number ofcompanies entered the POC testing market in the recent years while bringing significant technological improvements andnovel concepts to this market. Yet, many important needs for immunodiagnostics are unmet: POC tests still require relativelylarge volumes of samples, cannot readily be multiplexed, are not always accurate, and often involve simple liquiddisplacement ""from point A to point B"" with minimal control over the distribution of reagents and kinetics of reactions.Here, we propose a synergistic project aiming at developing simple-to-use and high-performance microfluidic capillarysystems (""CAPSYS"") for POC testing. Each part of the project will correspond to a complete PhD work with specific skills,methodology, and know-how from the academic and industrial PIs. The common theme for both projects will be the use ofcapillary forces for the autonomous filling of microfluidics by samples and liquids and the integration of reagents andreceptors for analyte detection inside the microfluidic chips. Those microfluidic chips will allow 1-step assays, i.e. assayswherein a non-technical user only needs to load a sample to the chip for performing a biological test.CAPSYS will lead to a new state of the art in terms of POC testing with significant relevance in medicine and diagnostics.CAPSYS will therefore be ideal for early stage researchers (ESRs) in terms of learning various disciplines in depth, creatingnumerous opportunities for publishing, and working on problem-oriented research that can have an impact in the ""realworld"".""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Partial Differential Equations on Sets of Measures'.

assistant: **Concept**

Partial differential equations (PDEs) are ubiquitous in science, whether it is in physics, engineering, biology or economics, as they naturally arise in the modelling of continuous objects. Recently, several PDEs have been derived to characterize complex objects such as: the best response by a player facing a continuum of adversarial players, the optimal control used to manage a distributed system or also the free energy or rate function of some distributed physical systems. All the associated PDEs are written on a set of measures on a smooth finite dimensional domain and raise new and difficult analytical challenges such as regularity and stability of the solutions, or the existence of weak notions of solutions. A systematic understanding of those equations is missing at the time, but it would lead to: derive rigorously the PDEs form the underlying models, justify numerical computations and, most importantly, to prove quantitative estimates and several properties of the modelled systems, which are otherwise out of reach because of the absence of explicit solutions.The key challenges targeted in this proposal are concentrated on two PDEs on spaces of measures, which are for the moment only understood in particular regimes, often very simplified compared to their original motivations. The first one is the mean field game (MFG) master equation: we intend to obtain a precise theory of regularity which will then help us both to extend the actual theory to more realistic MFGs and to have a better understanding of the stability of MFG equilibria. The second one is the Hamilton-Jacobi-Bellman equation: we aim to obtain much more general stability properties in order to treat practical mean field optimal control problems and mean field physical systems. Moreover, we also plan t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Reforming Schools Globally: A Multi-Scalar Analysis of Autonomy and Accountability Policies in the Education Sector' under Horizon 2020.

assistant: **Concept**

Most countries in the world are facing reform pressures to make their education systems more effective and responsive to the new challenges generated by the global economy. In this scenario, managerial policy ideas such as school autonomy and accountability, which aim to modernize public education and strengthen its performance, are spreading broadly. To date, a wide range of countries with different administrative traditions and levels of development have adopted school autonomy with accountability (SAWA) policies, whilst the most active international organizations in the education sector, like the OECD, are strongly promoting them globally.Constituting SAWA as a global model of education reform generates two main questions. First, why and how are SAWA policies disseminating globally, and to what extent does this reform model generate international policy convergence in education? Secondly, how and under what particular contextual and institutional circumstances do SAWA policies work and for whom? The fact that existing scholarly research has achieved inconclusive and mixed findings concerning the SAWA effects on learning outcomes and equity makes this second question especially relevant.To address these gaps in existing literature, REFORMED develops a comprehensive research approach that scrutinizes the different, but mutually constitutive stages of global education policy, from the inception in global agendas stage to their operationalization and effects in multiple contexts. Specifically, the project analyzes how and why SAWA policies are being adopted and re-formulated by policy actors operating at different scales (from international bureaucrats to teachers), and inquires into the institutional frameworks and policy enactment processes that explain the different e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'FISH-LIVER-HARVESTER (FLH) Project - an automated fish liver harvesting machine'.

assistant: **Concept**

The application is for developing a new machine, Fish Liver Harvester (for harvesting fish livers from codfish) from a TRL(Technological Readiness Level) 6-7 to TRL level 8-9. The working principle of the machine is utilizing the differences inspecific gravity of the livers and the rest of the guts, separating them in a flow of sea water running through the machine. Thelivers are floating in sea water, getting the livers to seek upwards, while the rest of the guts are seeking downwards. Theseparation is performed by a rotating separator, synchronized with conveyor carriers on the conveyor belt in the machine,and driven by the conveyor chain, separating the livers from the guts over a sharp edge. The livers are flowing with theseawater out of the machine, while the conveyor carriers are bringing the rest of the guts out at the other end of the machine.The actual machine is a Prototype 2 machine construction, which is based on the experiences made with a Prototype 1machine, which was tested onboard two Faroese trawlers, Sjagaklettur and Hamranes.The experiences made with Prototype 1, feedback from the crew onboard the trawler Hamranes, and good cooperationwith the Faroese Food Authorities were used in the design of a easier cleanable, more hygienic Prototype 2. Prototype 2 wasinstalled on board trawler Hamranes in December 2016 and is still being tested on board. The feedback from the crew onHamranes has been positive and a number of trawlers have already indicated purchasing interest.The intention is to optimize the machine and the yield and bring it ready for commercialization.The machine can make it possible to utilize a mostly wasted resource, that can be used both for food and feed production.The machine was developed for deep sea trawlers, but can also be adapted to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'SOCLE - SOCial SeLEction in cultivated plants'.

assistant: **Objectives**

As early shown with social insects, natural selection can maximize group performance by favouring the evolution of altruistic phenotypes. Such social selection has been shown to occur in a wide range of taxon, mainly in animals and microorganisms. Conversely, we have a very poor knowledge of social interactions in plants, mainly because the study of plant-plant interactions has largely remained disconnected from social evolution theory. For example, we don’t know which plant traits have social effects, and we don't know to what extent plant group performance can be affected by social effects. Better understanding social interactions in plants could open new opportunities for plant breeding. Indeed, it has long been suggested that crop yields could be increased by selecting more cooperative varieties. Moreover, advances in animal breeding based on social evolution have already shown convincing results. The aim of this project is thus to better understand social interaction in plants, using crops as a model system. Based on a competition experiment, I will use three approaches: a trait-blind approach, a trait-based approach, and a genomic approach. In the first approach, I will use the indirect genetic effects (IGE) framework to quantify the amount of heritable variation on crop yield that is due to social interactions, and compare it to the non-social heritable variation. With the second approach, I will test the social effects of a set of ecologically and agronomically important traits in order to identify those that contribute most to social interactions. Finally, I will use a genomic approach to look for genomic regions involved in social effects. Conducted in collaboration with plant breeders and leading scientists in the field of social evolution, this multi-discipl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The independent and interactive effects of multiple stressors on reproduction and development in cetaceans' (CETACEAN-STRESSORS).

assistant: **Concept**

Low reproduction rates (26% pregnancy rates, 3-4 year calving intervals) in two geographically isolated common dolphin Delphinus delphis populations in North East Atlantic (NEA) and New Zealand (NZ) have been found compared to other common dolphin populations where higher pregnancy rates (>40%) exist.  The causes of these low rates of reproduction in NEA and NZ are not known but contributory/causal factors may include nutritional stress, immune suppression, disease, pollutants and density dependent population effects. Studies that quantify the complex interacting and potentially confounding effects of multiple stressors on reproduction and development in cetaceans (including synergistic, antagonistic, additive and temporal effects) are urgently required. This project will systematically quantify a range of potential causal factors underpinning the low female fecundity rates in NEA and NZ populations by directly assessing stress and reproductive hormone levels, nutritional condition, reproductive and health status using state of the art (histo)pathological, molecular and other analytical techniques on samples obtained from a large number of postmortem examinations.  Interactions between these and other potential causal factors and mating strategies in both sexes derived from behavioural studies of wild common dolphins in Hauraki Gulf, New Zealand will be robustly tested statistically at individual and population levels.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Biosensor feed-back control of waste water purification: photooxidation followed by biological degradation using highly active surfactant degrading bacteria' (BIOFEED) under Fifth Framework.

assistant: **Objectives**

The BIOFEED project presents new scientific ad technological approaches for the wastewater clean up from surfactants. Detoxification process combines two steps: photo oxidation (ozone treatment with impulse UV irradiation) and bio sorption-biodegradation. Genetic screening technology will be used for selection of new highly active natural bacterial strains capable of effective degradation of surfactants. Optimisation and control of a surfactant clean up will be performed by feedback control of the processes based on the analysis of water samples with several types of microbial biosensors, CG/ LC/ MS, and ecotoxicity tests. The kinetics of biodegradation, biosensor construction, and pattern recognition of biodegradation profiles are among the objectives of investigation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Nonequilibrium physics from complex fluids to biological systems', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

The inherently interdisciplinary nature of nonequilibrium physics, in particular in the specific setting of this project, provides exceptional training opportunities for young researchers. These will be integrated in a rich and fertile environment where a variety of cross-expertise has been assembled to optimize both research performance and training through research. Young researchers will obtain advanced training in a variety of forefront experimental techniques, conceptual tools and computational methods in the field, with a fruitful interplay between theory and experiment. Training will be fostered by intensive workshop activities (up to 5 full-network meetings) including some school-format meetings specific for training of physicists in biological desiderata, in particular molecular cell biology. Exchanges and visits will be systematically implemented to ensure broad and deep training through collaborative work.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Complex Systems for an ICT-enabled Energy System' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The European Energy Policy aims at achieving three core objectives: sustainability, competitiveness and security of supply. The achievement of these objectives requires a profound transformation of the energy system that will imply a huge and coordinated effort across several areas. This effort must rely on a sound analysis of different policy approaches, regulatory measures and technological choices. ICT must play a key role as one of the enablers of the energy system transformation, but also as an enabler of new advances in the modeling, analysis and governance of the system.The energy system is a clear example of a large-scale sociotechnical system composed by a myriad of heterogeneous elements working at different scales. The complex behaviour that emerges from these interactions drives classical modeling methods to their limits. Complex Systems Science is emerging as a discipline capable of offering new methods for a realistic, robust and flexible modeling of such kind of systems. New tools such as Agent-Based Simulation or Complex Networks have led to valuable results in several fields, but their application to the energy system still faces a number of open issues that require further research.ComplexEnergy is a support action whose purpose is to bridge the ICT, Energy and Complex Systems research communities in order to:- build the foundations for a new, EC-scale, interdisciplinary research community able to formulate innovative approaches to energy system modeling, design and governance;- carry out a well-defined and systematic consultation of these three research communities, as well as of policy makers and other relevant stakeholders, with the aim to identify the main strategic areas, the emerging research avenues and the major research challenges at the junct
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Differential Program Semantics' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Traditionally, program semantics is centered around the notion of program identity, that is to say of program equivalence: a program is identified with its meaning, and programs are considered as equal only if their meanings are the same. This view has been extremely fruitful in the past, allowing for a deep understanding of highly interactive forms of computation as embodied by higher-order or concurrent programs. The byproducts of all this lie everywhere in computer science, from programming language design to verification methodologies. The emphasis on equality — as opposed to differences — is not however in line with the way programs are written and structured in modern complex software systems.  Subtasks are delegated to pieces of code which behave as expected only up to a certain probability of error, and only if the environment in which they operate makes this possible deviation irrelevant.  These aspects have been almost neglected by the program semantics community until recently, and still have a marginal role. DIAPASON's goal is to study differences between programs as a constitutive and informative concept, rather than by way of relations between them.  This will be accomplished by generalizing four major frameworks of program semantics, traditionally used for giving semantics to programs, comparing them, proving properties of them, and controlling their usage of resources: logical relations, bisimulation, game semantics, and linear logic.


**Keywords:** Programming Language Theory, Semantics, Lambda Calculus
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Selection of DNA nanostructures for multivalent binding and drug delivery' under Horizon Europe.

assistant: **Concept**

In nanomedicine, patterns, shapes and mechanics are tuned to improve performance in applications such as drug delivery and pattern matching binders. A fundamental bottleneck is that structures need to be individually assembled and tested limiting the number that can be screened and likely missing structures with optimal performance.  In this proposal we describe a new class of DNA nanostructures, assembled as diverse libraries of branched DNA wireframes with complex 3D shapes that fold from single stranded genomes. The structure genomes can be amplified and sequenced allowing us to test vast pools of structures in a single pot and amplify those with the best performance transforming nanomedicine from a design to a selection problem. This proposal has three objectives: First, we will refine the tools to assemble DNA structure libraries, perform selection and analyse the sequencing data to identify structures with optimal performance. Secondly, we aim to develop DNA based multivalent antibody alternatives by selecting DNA structures that can pattern multiple aptamers with respect to the epitope distribution on targets. We will target pathogenic proteins of both bacterial and viral origin to create a new route to rapid to develop / deploy binders for diagnostics. We also aim to construct multivalent binders that are specific for nucleosomes with multiple histone modifications. The interaction between DNA nanostructures and cells are controlled by geometry, mechanics and patterns of moieties. In our third objective we will use cell-type specific uptake a selection pressure to produce patterned DNA nanostructures that can deliver gene silencing RNA with specificity to diverse cell types, including cancer cells. By moving nanomedicine from single-pot rational design to an evo