RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Numerical Tool for Aerodynamic Optimization of Laminar Wings' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The classical numerical approach used for Natural Laminar Flow (NLF) design relies on the experience of the engineers in finding pressure distributions that would improve the extent of laminar flow and could reasonably be approximated in an inverse design phase. Recent initiatives improve this approach, eliminating the “man in the loop”, by including a measure of the laminar flow in the shape optimization problem itself. The numerical solution of such problems with many parameters and constraints is challenging. Our method of optimization for NLF design is an implementation of a gradient-based approach enabling us to efficiently solve problems with many design parameters. The use of CFD, followed by boundary-layer stability analysis, enables to directly find geometries that damp growth of disturbances (which cause transition) in order to delay the laminar-turbulent transition. Moreover, the computation of the gradients is efficiently performed thanks to the work carried out in last years at FOI and KTH on adjoints of the flow and stability equations, making the cost for computing gradients independent of the number of optimization parameters. Our method has been successfully tested for optimization of airfoils and has already come in use in several projects with industrial applications. In the scope of the present project the NLF-optimization toolkit (developed by FOI & KTH) will be extended to three-dimensional geometries. Another important improvement is to include the sensitivities with respect to flow separation because the extension of the laminar boundary layer at cruise can severely penalize the performance of the NLF wing at high angles of attack if laminar separation occurs too early. An attempt will be made to include the Reynolds Averaged Navier-Stokes (RANS)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Identification and characterization of new cytosolic ligands of Sortilin' to be submitted under Horizon 2020.

assistant: **Abstract**

Protein trafficking is crucial to maintain organelle function and cellular homeostasis, and is regulated by sorting receptors. Sortilin is a membrane receptor that sorts proteins to the predisposed cellular compartments through both secretory and endocytic routes. To accomplish this function Sortilin is endowed with an ectodomain that binds a great variety of cargo proteins, and a cytosolic domain that recruits adaptor proteins to direct the receptor trafficking activities. In the last 15 years more than 20 cargo proteins of Sortilin have been identified leading to the discovery of key Sortilin functions related to lipoprotein metabolism, neurotrophic factor signaling and lysosomal trafficking. However, little is known about the specific mechanisms that regulate Sortilin intracellular trafficking and function, since few cytosolic adaptors, shared with other sorting receptors, have been identified. Based on this, the aim of the present project is to identify and characterize new cytosolic adaptors of Sortilin and shed light on these fundamental aspects. In particular, I will isolate, validate and characterize new adaptors and their binding sites, starting from the outcome of a large-scale analysis of candidate Sortilin adaptors performed by the host research group. To this aim I will use multiple techniques developed for the study of protein-protein interaction and cell biology. The results of this study will provide new knowledge about the Sortilin binding ability, intracellular trafficking and function. Importantly, elucidating the machinery and the molecular/regulatory mechanisms of protein trafficking is crucial to understand cellular physiology and pathology. In addition, since Sortilin is emerging as a major disease gene in cardiovascular, neurological, and neurode
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Safe Driver Machine Interface (DMI) for ERTMS automatic train control', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

Railway automatic train control (ATC) systems are based both on trackside and on-board systems and their evolution has followed, step by step, the introduction of new technologies. The increasing level of train traffic and the spread of high-speed rail lines are now demanding an increasing safety level in the ATC systems. Up to now, each country has defined its own requirements specification for controlling the train movement and to ensure system safety.To ensure compatibility and interoperability between the ATC systems produced in the various European countries, the European Rail Traffic Management System (ERTMS) programme has been set up to provide unique functional and non-functional standard requirements. The ERTMS architecture for the on-board ATC encompasses a Driver Machine Interface (DMI) component. Its main functions are the acquisition of driver's commands and the display of that information that support the train driving.The objective of the SAFEDMI project is to design and develop a DMI system that distinguish itself from other trainborne DMIs currently available on the market by:- being able to satisfy at least SIL 2 according to CENELEC specifications with all the related implications;- being able to integrate in such safe DMI safe wireless communication interfaces for configuration, SW and firmware downloading and diagnostic purposes.The detailed proposed objectives are:- to design and develop a safe DMI integrated with the current on-board ERTMS systems developed according to the ERTMS Interface specifications- to study and develop all the HW and SW solutions to properly address the safety and fault tolerance issues generated by the SIL 2 requirements;- to integrated in the safe DMI safe wireless communication interfaces for configuration, SW and firmwa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Models with cross interactions between partial dynamical processes aiming to understand significant or abrupt dynamic changes.' (CrossInteractions).

assistant: **Innovation**

Bifurcation analysis of nonlinear models is a powerful tool that has a practical use since it detects and explains dynamical changes. It allows a description of generally emerging phenomena dependent on parameters. This project aims to understand significant or abrupt changes in dynamics of models related to cross-interactions between partial dynamical processes and study how these cross-interactions affect the system's behavior as a whole. The project covers three fields of applied nonlinear dynamics: population biology, neuroscience and epidemiology. Uncovering the dynamics of coupled prey-predator models (population biology), which includes persistence and extinction of the populations in cross-interacting patches, the emergence of periodic and aperiodic attractors, emergence of chaos, comparison of dynamics of the coupled model and the uncoupled one. Uncovering the dynamics of coupled neuronal subsystems with respect to possible/impossible abrupt dynamical changes and synchronized dynamics. Uncovering dynamics of coupled epidemic subsystems with emphasis on dynamics of COVID-19 epidemics to understand connections between dynamics of local and global outbreaks, interacting of sub-populations of various mutations and even seasonal effects. I expect following exploitation of the results: theoretical in mathematical biology (new knowledge in population biology, neuroscience and epidemiology), applied (new knowledge of suitable/unsuitable models with respect to bifurcations, qualitative dynamical changes and emerging nonlinear phenomena in real world systems), educational (models attract attention of students and facilitates study of difficult passages of abstract mathematics), and practical in applied mathematics. Part of the project is to strengthen the team of Prof. P
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Resurgence of plasmodium vivax malaria in the newly independent states (nis): development of innovative tools for monitoring parasite populations spreading, to potentiate surveillance and control of malaria outbreaks'.

assistant: **Objectives**

The project's goal is to develop modern tools for monitoring and preventing malaria outbreaks, and to integrate them into the surveillance health systems of NIS. The introduction of innovative technologies applied to malaria surveillance may represent a major impulse for a general improvement in monitoring re-emerging infectious diseases . The project will include three NIS with different malaria situations, namely Armenia, Azerbaijan and Uzbekistan. The project should fill major gaps in Plasmodium vivid malaria epidemiology in these countries. i.e. distribution and genetic composition of Victoria populations, geographical spread of parasite populations from borders and within the country and vector/parasite relationships. Molecular tools applied to investigate on these aspects shall be adapted in simple and low cost formats and employed at reference laboratory level in conjunction with traditional entomological and parasitological methods.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Shelf.ai - Holding back Amazon and Google from the global grocery retail market' (2014-2020).

assistant: **Concept**

Enabled by Xarevision, a company with over 10 years 'experience working on retail-oriented solutions for large players, Shelf.ai is a cutting-edge technology that brings artificial intelligence and conversational commerce capabilities to brick & mortar food retailers, allowing them to foster omni-channel strategies, rapidly increase online sales and pioneering next wave of customer e-shopping experience.With Shelf.ai, customers can build their shopping carts just by saying the products and quantities they wish to their smartphones, and select the ones they prefer, proceeding immediately to check-out. Through direct integration with the retailers’ back-end systems (including product ranges, customer purchase information and payment platforms), Shelf.ai allows customers to see full details of each product, while employs AI algorithms in order to continuously improve the system by learning about customers’ preferences.Shelf.ai’s technology allows an overall reduction up to 90% of the time required from login to filling up the online shopping cart, providing the easiest, coolest and fastest online grocery shopping experience ever seen. Moreover, Shelf.ai positions itself as a hardware-agnostic platform (working through Smartphones, Amazon Alexa, Google Home, Facebook Messenger and others) that allows brick & mortar retailers to fight back the fast and disruptive penetration of giant online platforms (Amazon and Google) in the global grocery retail market. Shelf.ai will focus primarily on world-class food retailers, expecting to reach in these segment alone an annual turnover of Euro 45 Million.Shelf.ai has been already tested and demonstrated in a relevant environment (namely in Euroshop 2017) delivering highly effective results that have been gathering the attention of som
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Commercial feasibility of a cell-free reactor setup  for optimisation of complex enzymatic pathways'.

assistant: **Objectives**

This project will explore the commercial feasibility of the first continuous stirred tank reactor solution for the synthetic replication and optimisation of complex enzymatic pathways. Our technology provides an urgently needed alternative for bioengineered organisms. Where normally raw materials of varying quality, competition between intermediates, toxicity, complex networks of feedback loops and other poorly understood factors limit production rates, our approach can be used to converge effectively to optimised biochemistry .As part of the project, we will establish two industrially relevant pathways, advance the software solution of our platform and develop a commercialisation strategy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Multi-property Compositionally Complex Magnets for Advanced Energy Applications' (CoCoMag).

assistant: **Innovation**

Converting energy efficiently from renewable sources is crucial; however, the large-scale implementation of technologies such as e-mobility and wind turbine but also magnetic refrigeration will increase drastically the material intensity of strategic metals like rare-earths (RE) and cobalt. Magnets are key enablers of a net-zero emission scenario. As conversion technologies become more advanced, the required attributes of the magnets are now much more demanding and multifunctional, additionally required mechanical, thermal, mechanical stabilities will increase efficiency and lifetime of the devices. We live now in a cryogenic age and gas-compression cooling has not been changed for a century, with only incremental efficiency improvements over time. Magnetic refrigeration uses not only Nd-based permanent magnets, the same as used for the e-motor, to drive the magnetic heat pump but also heavy REs such as Gd for the magnetocaloric heat exchanger. In the CoCoMag proposal, we are targeting these two main applications, e-mobility and magnetic refrigeration, by implementing a disruptive approach for magnet design. Our idea is the use of compositionally complex alloys (CCA) based on hexagonal Fe2P- and MM´X-type compounds, derived from high entropy alloys, for the development of both permanent magnet and magnetocaloric materials without critical elements. With CCA, we can fully utilize the large degrees of freedom in the compositional space in a multi-element approach, leaving behind traditional metal alloying practised since Bronze Age. Using CCA, we address the primary magnetic properties AND the above equally important secondary engineering properties. We will use the theoretical predictions, experimental validation and machine learning cycle to reach our goals fast. Being
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Ultrahigh-speed nanometer-scale microscopy'.

assistant: **Concept**

Ultrahigh-speed microscopy at Tera-scale frames per second frame-rate is essential for various applications in science and technology. In particular, it is critical for observing ultrafast non-repetitive events, for which the pump-probe technique is inapplicable. The spatial resolutions of such microscopes is to date limited to the micrometer scale.I propose to develop such microscopes with nanometric resolution.The Tera-scale frames per second frame rate microscopes with nanometric resolution will be based on a new approach for ultrahigh-speed imaging that we recently proposed: time-resolved imaging by multiplexed ptychography (TIMP). In TIMP, multiple frames of the object are recovered algorithmically from data measured in a single CCD exposure of a single-shot ptychographic microscope. The frame rate is determined by the light source (burst of pulses) and it is largely uncoupled from the microscope spatial resolution, which can be sub-wavelength. Also important, TIMP yields movies of both the amplitude and phase dynamics of the imaged object. It is simple and versatile, thus it can be implemented across the electromagnetic spectrum, as well as with other waves.I aim to develop TIMP-based microscopes, in the visible, extreme UV and x-ray spectral regions with Tera-scale frames per second frame rate and nanometric resolution. We will utilize the unprecedented imaging capabilities in applications, including exploring ultrafast phase transitions, ultrafast dynamics in nanostructures, and tracking the spatiotemporal dynamics during passive mode-locking build-up in lasers and Kerr micro-resonators.This program, if successful, will bring the field of imaging into a new era, where ultrafast dynamics of non-repetitive transient complex-valued objects can be viewed at nanometr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Enhancing the Scientific Excellence of TUBITAK MRC MT in Ceramic Membrane Fabrication for Industrial Wastewater Recovery Applications via Knowledge Transfer and Capacity Building'.

assistant: **Objectives**

Due to rising water demand and an increased focus on sustainability, ceramic membranes, known for their superior chemical and thermal resistance, are becoming increasingly important in recovering industrial wastewater. With a CAGR of 11.9%, the European ceramic membrane market is anticipated to reach 3.5 billion US dollars by 2030.The number of projects and R&D studies on ceramic membranes in Turkey is quite limited; there is not yet sufficient awareness about the necessity of ceramic membranes in the industry, and commercial production of ceramic membranes cannot yet be carried out. TÜBİTAK Marmara Research Center (MRC) is Turkey's leading research center producing science and technology with its research, development, and innovation capabilities. Material Technologies Vice Presidency (MT) of TÜBTAK MRC, with its interdisciplinary knowledge and human capacity in both ceramic and sol-gel technologies, can fabricate and characterize MF, UF, and NF tubular ceramic membranes on a laboratory scale. However, it has challenges regarding ceramic membrane substrate fabrication, scaling up, and ceramic membrane layer modification, limiting the real-life industrial usage for wastewater recovery.The Twin-CeraMem aims to meet the requirements of the HORIZON-WIDERA-2023-ACCESS-02-02 Twinning Green Deal Call. The main objective of this project is to increase the scientific, innovative, and administrative excellence capacity of TUBITAK MRC in the field of ceramic membrane fabrication for industrial wastewater recovery applications in order to support the sustainable use of water as a natural resource.This main goal is to be achieved with the support and mentoring of leading European partners Fraunhofer IKTS (Germany), which specializes in ceramic membrane substrate fabrication, and VI
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Finding order to harness chaos: A new approach to understanding and controlling high Reynolds-number wall-bounded turbulence' (WBT).

assistant: **Concept**

The enormous impact and significance of high Reynolds-number wall-bounded turbulence in various applications ranging from transportation and energy generation systems to meteorology and oceanography cannot be understated. However, almost all existing ideas in modelling and controlling wall-bounded turbulence are based on our limited understanding of low Reynolds-number flows. In higher Reynolds-numbers, we simply assume the existence of mutual independence of the large-scales located farther away from the wall from the small-scales near the wall and vice-versa. However, this notion of independence is incorrect. In fact, multiscale interactions between large- and small-scales play a significant role in various turbulent transport processes in practical situations. Consequently, our predictive models and control schemes that cannot account for or take advantage of these interactions have very limited success. Therefore, the central question posed in this research project is: What is the physics of scale interactions at higher Reynolds-numbers and how do we take advantage of it?The aim is to explore the essence of scale interactions and develop fundamental understanding by performing novel experiments in high Reynolds-number boundary layers. New control methodologies based upon the existence of interactions between large- and small-scales will be devised and applied to reduce skin-friction drag. Additionally, unconventional, yet highly innovative experiments will be devised to ``simulate'' essential aspects of high Reynolds-number scale interactions in a controlled laboratory environment. State-of-the-art laser diagnostics techniques including tomographic PIV and multiple-plane PIV will be performed together with other methods such as hot-wire/laser anemometry to study the