RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Helical Out-of-Equilibrium Systems: Exploring Light-Induced Structural Distortions' (HeliOS).

assistant: **Concept**

Helical architectures are prevalent in natural and artificial settings due to their mechanical robustness, chiroptical properties, and ability to assemble compactly through intra- and intermolecular interactions. We propose that reversible distortions to these structures can unlock new behaviors. Inspired by recent advancements in supramolecular chemistry and light-responsive molecules, we aim to couple light-responsive units (LRUs) to helical structures to drive them out-of-equilibrium (OOE), thereby modulating their functionality and achieving photoactuation. Adopting organic and metal-organic spring-like model systems, we aim to achieve compression, extension, and complete unwinding of the helices under photoirradiation. In the OOE state, we hypothesize that the systems can store and release energy, making them promising candidates for optomechanical work and offering an alternative design strategy for molecular solar-thermal (MOST) materials. Furthermore, our approach enables the precise placement of LRUs within the helical structure, which is anticipated to provide customized optomechanical responses, such as bending and twisting, and allow new light-gated reactivity and feedback loops. Expanding this concept, we will explore larger, polymeric versions of these materials in bulk, such as films and fibers, to achieve light-powered translation, rotation, and lifting of objects. This fundamental study establishes a new research area focused on using LRUs to perturb discrete helical structures OOE, advancing the current approaches to perform mechanical work on the macroscopic level and presenting a novel design approach for MOST materials. Success will undoubtedly catalyze interest in exploring other helical architectures beyond the model systems studied here, achievin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Oestrogens and age-related urogenital diseases: basic and clinical approaches', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

1/3 of Europeans are over 55 years old, when conditions such as eudiometrical cancer, vaginal dryness, benign prostates hyperplasic, prostrate cancer and urinary incontinence are common, with increased healthcare costs and reduction in quality of life and mobility. The lack of oestrogens appears causally linked to the development and progress of such diseases. (E) UROESTROGEN (E) S aims to promote the development of selective estrogens receptor modulators (Serums) with reference to phyto-SERMs. 5 partners at 4 universities belong to the European thematic network EUROSTERONE, with excellent laboratory infrastructure and access to patients. The research will lead to concepts for clinical trial and well-tolerated phyto-SERMs beneficial in the human argental tract. This will both aid the ageing population, and be of great socio-economic impact throughout Europe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'A scalable semiconductor quantum computation platform based on Ge hole spin-qubits in rhombic quadruple quantum dots in strained Ge/SiGe'.

assistant: **Concept**

I propose a 24-month MSCA Postdoctoral Fellowship in experimental condensed matter physics to overcome limitations in coherence time, single-gate operation frequency, and scalable readout associated with challenges in realising quantum computers. DEMETER builds on the complementarity of my strengths, the leading fabrication expertise and infrastructure at my Host, Tyndall National Institute, and the know-how in quantum information processing afforded by a secondment at the high-potential UK SME Quantum Motion. I will use Ge as an emerging quantum material platform to realise Ge-hole spin qubits in strained Ge/SiGe heterostructures and gate-defined RQQDs formed in the underlying Ge. DEMETER aims to demonstrate a beyond state-of-the art scalable qubit platform using the emergent architecture of Rhombic Quadruple Quantum Dots (RQQDs) and the Ge material platform. Using this novel architecture and exploiting advances in fabrication processes, rf-based novel techniques – that is rf single-electron transistor (RF-SET) and gate-based sensing   for qubit readout will be implemented offering scalability through integration of both the qubit realization and control readout. My specific science and technology objectives are to achieve advances in the coherence time, fast qubit operation and fast readout, and to contribute towards the scalability of quantum microchips. My career development will benefit from the supervision of Dr Giorgos Fagas, an established leader at Tyndall, the Irish quantum technologies community and the EU landscape, and the research expertise in processing Ge nanostructures of Drs Duffy and Petkov. During my 2-month secondment, I will be supervised by Dr. Fernando Gonzalez-Zalba who is a leading researcher in gate-based sensing reflectometry. The goal of the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for '3D Printing of Cell Laden Biomimetic Materials and Biomolecules for Joint Regeneration' (JointPrinting).

assistant: **Innovation**

Osteoarthritis (OA) is a serious disease of the joints affecting nearly 10% of the population worldwide. Realising an efficacious therapeutic solution for treating OA remains one of the greatest challenges in the field of orthopaedic medicine. This proposal envisions a future where 3D bioprinting systems located in hospitals will provide ‘off-the-shelf’, patient-specific biological implants to treat diseases such as OA. To realise this vision, this project will use 3D bioprinting to generate anatomically accurate, biomimetic constructs that can be used to regenerate both the cartilage and bone in a diseased joint. The first aim of this proposal is to print a mesenchymal stem cell laden biomaterial that is both immediately load bearing and can facilitate the regeneration of articular cartilage in vivo, such that the bioprinted construct will not require in vitro maturation prior to implantation. Mechanical function will be realised by integrating an interpenetrating network hydrogel into a 3D printed polymeric scaffold, while chondro-inductivity will be enhanced by the spatially-defined incorporation of cartilage extracellular matrix components and chondrogenic growth factors into the bioprinted construct. The second aim of the proposal is to use 3D bioprinting to create a cell-free, composite construct to facilitate regeneration of the bony region of a large osteochondral defect, where vascularization will be accelerated by immobilizing spatial gradients of vascular endothelial growth factor into the implant. The third aim of the proposal is to scale-up the proposed 3D bioprinted construct to enable whole joint regeneration. Finite element modelling will be used determine the optimal structural characteristics of the scaled-up implant for it to fulfil its required mecha
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The development and evaluation of Multipurpose crops as new biorefining feedstocks for the production of industrial BioProducts and biomass' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The overall strategic objective of MultiBioPro is to exploit natural resources from genetic varieties of two industry-utilized plant species, poplar and the tobacco tree Nicotiana glauca, for direct applicability to novel industrial end products. The consortium will explore already existing poplar and N. glauca genotypes in parallel with innovative state-of-the-art translational research from the model organism Arabidopsis to genetically engineer metabolic pathways to advance qualities of wood fibers, and long-chain fatty acids. The modulation of fiber and long-chain fatty acid quality in both poplar and N. glauca will be examined through a multidisciplinary analytical platform that will optimize for key industrial values. An extensive cross-talk between the analytical platforms, biorefining and field trials will provide the basis for industrial determination of N. glauca and poplar varieties as new multi-purpose feedstocks. Importantly, residual biomass, e.g. suberin in poplar bark, that normally is considered waste products will also be analysed for its potential to yield long-chain fatty acids with important characteristics for new bio-materials and for biorefinery purposes. Both poplar and N. glauca may readily be grown in areas that are sub-optimal for food crop-species, and field-trials within the MultiBioPro project will further evaluate the environmental sustainability of the obtained poplar and N. glauca genotypes. Attributes that are advancing biorefinery and bio-material properties will be further exploited for marketing, demonstrating the industry-driven nature of the MultiBioPro consortium. Dissemination and training events will constitute an integral part of the project, and will include training modules in using different analytical platforms, industry-le
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Identification of Mechanisms Correlating with Susceptibility for Avian Influenza'.

assistant: **Objectives**

IMECS is a proposal of the FLUSECURE network aimed at combating the threat of new and re-emerging forms of highly pathogenic influenza in its first stages of a disease by identifying mechanisms of protection that are essential for a solid immune response to avian influenza. IMECS is uniquely featured by correlating research in humans directly to protection from influenza.  The IMECS initiative was introduced since the recent H5N1 avian influenza vaccine trials results have shown limited success in inducing a protective immune response as compared to the standard human influenza vaccines. This despite large investments and multiple vaccine formulations tested. These results make clear that the mechanisms of immunity for avian influenza are inherently different from those for human/seasonal influenza. The IMECS initiative aims to elucidate these mechanisms and aims to provide essential knowledge for development of breakthrough pandemic vaccines as a result. The initiative thereto boosts the development of AI-correlates of protection for the clinical screening of vaccine candidates in healthy adults and in different target groups, the origin of subclinical AI infection in humans, as well as a research programme for the screening of vaccine candidates in vitro. The following research objectives are pursued:  - Determining the basis of the homologous and non-homologous mechanisms of protection for avian influenza; - Determine the mechanisms of protection in specific target groups, including infants and the elderly; - Determining the AI-specific response after vaccination in clinical trial studies. IMECS combines the knowledge of leading European universities and research centres. The multidisciplinary consortium has the resources, skills and knowledge to realize the objectiv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Biphasic Plasmonic Photoelectrocatalytic CO2 Reduction: electrochemically controlling plasmonic photo-charging of metallic nanofilms at immiscible liquid|liquid interfaces towards CO2 reduction', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Conversion of CO2 to synthetic fuels is essential for climate-change mitigation and renewable energy production. This project will develop a novel, disruptive and sustainable approach to the photoelectrocatalytic CO2 reduction reaction (CO2RR). The interdisciplinary methodology will combine breakthrough approaches to self-assemble nanoparticles into metallic nanofilms at fluidic interfaces, with electrochemical control of ion and electron transfer at an immiscible liquid|liquid (L|L) interface, and custom in situ UV/vis and Raman setups to probe the electrified L|L interface. The major innovation will be unprecedented electrochemical-control of the degree of plasmonic photo-charging of the interfacial metallic nanofilms to overcome the kinetic bottleneck of the multielectron, multiproton CO2RR towards more energy-dense C2 or C3 hydrocarbons. This MSCA-IF will significantly support the EU’s goal to decarbonise the energy sector, detailed in the European Green Deal, via high-impact scientific research and intellectual property generation for environmentally-friendly technologies. The Experienced Researcher (ER) will be supervised by Dr Micheál D. Scanlon at the University of Limerick (UL), Ireland, and undertake a secondment with Prof. Steven Bell at Queens University Belfast (QUB), U.K. The ER will engage in well-structured dissemination activities of the project results both to expert scientists and the general public using a multitude of engagement and outreach platforms. While the ER is accomplished in spectroelectrochemistry and nanomaterials synthesis, this fellowship will greatly expand his core scientific experimental and communication skills, international outlook, and broaden his professional network and inter-sectoral employability. Ultimately, this enhanced re
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Changing biodiversity in changing environments: Trait Changes across space and time' (TraChange).

assistant: **Concept**

Global concern about human impact on biological diversity has triggered an intense research agenda on drivers and consequences of biodiversity change in the Anthropocene. Recent evidence across biomes and taxonomic groups has revealed variable spatial patterns of losses and gains. However, little is known about the characteristics (i.e., traits) of the outgoing and incoming species in local assemblages undergoing rapid compositional turnover. Nor is it known how the magnitude of the different environmental drivers (e.g., climate change, land use change) influence such patterns. This points to a clear need for a deeper understanding of (I) identities and traits of incoming and outgoing species, (II) spatio-temporal differences in community trait distributions, and (III) the possible drivers behind such differences. The project aims to tackle this knowledge gap by determining whether there are consistent and directional changes in community traits unfolding in the Anthropocene. I will conduct in-depth studies at two different levels of ecological organization (species and community), using a range of modelling approaches to further our understanding of large-scale trait changes and test key assemblage trait distributions hypotheses. This will require the integration of research from diverse disciplines, including the development of new methods and tools. The research is proposed as a 2-year EF. USTAN will be the beneficiary host, while UoN will host me for two 2-month-long secondments. This MSCA will allow me to build a novel scientific profile, consolidate my position in the field, and progress towards achieving professional maturity. This research has great potential for scientific advancement and it will open up the best career possibilities for my career and new colla
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'New approaches to insulated molecular wires derived from polyaniline' (2002-2006).

assistant: **Concept**

Recent research in Oxford has shown that conjugated polymers can be threaded through organic macrocycles, such as cyclodextrins, to form polyrotaxanes which behave as insulated molecular wires, resulting in enhanced fluorescence efficiency, electroluminescence efficiency and chemical stability.We now aim to encapsulate polyaniline. Polyaniline can easily be doped by protonation, as well as by oxidation, increasing the conductivity by 10 orders of magnitude, almost to that of a conventional metal. It has emerging applications in rechargeable batteries, sensors, electromagnetic screening fabrics and electrochromic devices. It is known to bind beta-cyclodextrin to form polypseudorotaxanes, but these labile inclusion complexes have never been capped to generate robust rotaxanes.The aim of this project is to synthesise a series of amino-terminated oligoanilines and to investigate their interaction with macrocycles such a beta-cyclodextrin and cucurbit[7]uril. We expect that pseudorotaxanes will be formed, and that it will be possible to cap the ends of the oligomers with bulky electrophiles to generate polyrotaxane-type insulated molecular wires.The chemical, photophysical and optoelectronic characteristics of these insulated molecular wires will be investigated, to explore whether metallic conductivity is preserved in insulated polyaniline chains. Rienk Eelkema is currently completing his PhD thesis on Liquid Crystals as Amplifiers of Molecular Chirality in Groningen with Professor Ben Feringa. He has great expertise in the molecular-scale design of novel functional organic materials, together with a strong grasp of supramolecular chemistry and photochemistry, all of which will enable him to make an outstanding contribution to this project.The fellowship will extend his exp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'A RELIABLE, EFFICIENT, FLEXIBLE AND COST FFECTIVE VANADIUM-REDOX BATTERY ECHNOLOGY FOR  LARGE SCALE ELECTRICITY STORAGE: A NOVEL SOLUTION FOR A GREEN GRID.' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Hydraredox Iberia S.L. is a Spanish SME formed as a joint venture between Hydraredox Europe Ltd and Kern Strategies & Developments, S.L. combining their skills and resources to develop and commercialize large-scale Electrochemical EnergyStorage Systems (EESS). Our EESS are based on our patented vanadium-redox battery technology, which is the result of extensive research performed in the field over many years. Hydraredox has developed the only system on the market which overcomes all the major problems currently affecting large-scale electrochemical energy storage. Hydraredox’s high efficiency, long-duration storage-, long life, high operational safety and environmental performance, and commercially viable costs make it optimal for the integration of renewable energy in the electric grid.Hydraredox has successfully performed all the basic research and has already brought the technology to a demonstration scale: a 5 kW demonstration plant is installed and operated at our facilities in northern Spain. At a TRL7, our system has proved 100% reliable, high global energy efficiency (>80%), total suitability for large scale energy storage for renewables and for the electricity grid, cost efficiency (price of <580€/kWh compared to other ES systems >1.000€/kWh), no safety/environmental issues, and very long life of 30 years, twice that of other systems currently on the market.In order to move forward with our roadmap towards the commercialization of our EESS for large scale energy storage, in the VR-Energy project, we aim to further scale up our vanadium-redox battery system to 500 kW power with an energy storage capacity of 4 MWh for its actual implementation in the renewable electricity grid. The ultimate goal of our participation in the project is to become a worldwide leader