RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Advanced Multimedia Parallel Accelerator' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Recent multimedia workstations and networks are capable of handling complex information formats like sound and video, making it practical to implement applications like CSCW and video-conferencing. However, the requirements of high quality images for broadcasting and some of the advanced applications like Virtual Studios, tele-presence and Virtual Reality require much more powerful facilities than are available today. In order for some of the important advances to be achieved in the above fields to reach the mass consumer markets, the underlying costs of such facilities need to be reduced considerably.A number of ACTS projects, in particular in the Multimedia Services Domain, include hardware support targeted to specific requirements. It is important that a consistent approach within a framework exists so as not to dissipate effort in a number of specialised hardware implementations. In fact MPEG-4 is attempting to define a comprehensive overall framework with a whole range of profiles and levels as already defined, so as to standardise a number of state of art image coding and multiplexing techniques. As such standards are accepted for new television broadcasting services and as the basis for multimedia services via telecom networks, it becomes important that architectural support is developed to implement these.The detailed specification for an Advanced Multimedia Parallel Accelerator (AMPA) proposed to be built by the Consortium has been completed and presented at the ACTS Concertation meeting. This platform provides a high performance architecture designed for processing real time video and data streams and combinations of these for advanced multimedia applications. AMPA can be implemented at multiple levels, allowing a range of costs and performances to be based on
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'ADVANCED ROUTE OPTIMISATION AND IMR TECHNIQUES FOR SUBMARINE PIPELINES' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

To enhance and integrate existing advanced techniques for survey data acquisition, pipeline behaviour simulation and fitness for purposes assessment of subsea pipeline systems, including marginal and deep water developments.To demonstrate the application of these advanced techniques for route optimisation and IMR by means of an Offshore Field Test.To have the route optimisation and IMR elements of the packaged tested by potential end users namely a pipelay contractor and pipeline operator.To disseminate the results of the project to the oil and gas industry through the proposers global network of offices, leading to commercial exploitation of the technology. The demonstration of a pipeline simulation that includes a realistic contact model of seabed/pipeline interaction. The use of seabed discrimination survey techniques to determine the nature of the surface, and inclusion of this geotechnical data whithin the seabed model of the pipeline behaviour simulation.The demonstration of problem solvers covering spanning, upheaval buckling, onbottom stability, mud-slides and trawl-board pullover for the purpose of route optimisation and fitness for purpose assessment.SIMULATOR problem solvers covering on-bottom stability, spanning and upheaval buckling are available from JP Kenny.The SIMULATOR project will provide an improved quality of engineered assessment of the behaviour and fitness for purpose of a pipeline system throughout the design, installation and operating phases of its life.The project will have two modes of operation namely route optimisation and Inspection, Maintenance and Repair (IMR). In the route optimisation mode a wide variety of survey/soils information will be gathered including swathe bathymetry, seabed sediment data by acoustic discrimination methods, g
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Eranet Sustainable Urbanisation Global Initiative' (EN-SUGI) targeting Horizon 2020.

assistant: **Abstract**

Cities around the globe are struggling to meet the needs of their citizens with respect to food, energy and water. These three sectors are inextricably linked and actions in one sector more often have impacts in one or both of the others; these interacting sectors can therefore be seen as a Food-Energy-Water Nexus (FEW Nexus) of systems. The ERANET Sustainable Urbanisation Global Initiative (EN-SUGI) will bring  together the fragmented research and innovation expertise across Europe and beyond to find innovative new solutions to this FEW Nexus challenge. Furthermore, by linking the activity of the Joint Programming Initiative (JPI) Urban Europe and the Belmont Forum (BF), EN-SUGI develops more resilient, applied urban solutions that bring research and innovation together from across the globe.EN-SUGI is a project that foresees the participation of 19 Funding Agencies eligible for the EU top up, 18 from JPI Urban Europe and 1 from Argentina, and 6 FAs non eligible for EU top up, under the umbrella of the Belmont forum , collaborating on a volunteer base.EN-SUGI Main objectives and impacts are:To support development of practical innovations and new collaborative research that will allow urban areas to understand and address the challenges of the Food-Energy-Water systems. (Impact = 12-14 projects funded, and 15 cities/local authorities engaged)To provide a framework for aligning R&I agendas of JPI Urban Europe and the BF,. The alignment will help foster transdisciplinary collaboration and co-creation in research and innovation, and facilitate the use of global expertise and knowledge (Impact = 24 funding organisations involved)EN-SUGI will foster development of international relationships between the different parts of the research and innovation community – to enable the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Extracellular vesicles as a tool to predict drug clearance and improve precision pharmacotherapy' in the context of a Horizon 2020 call.

assistant: **Objectives**

Drug transporters of the ATP-binding cassette (ABC) family (e.g., P-gp, MRP2 and BCRP) promote the intestinal, biliary and urinary excretion of a wide range of drugs and, thus, determine their bioavailability, therapeutic efficacy and toxicity. Transporter expression is highly variable between individuals and within the same individual. This may result in enormous differences in the plasma concentration of a drug, which for drugs with a narrow therapeutic index may result in life-threatening situations. Extraction of biopsies would be the only option to measure transporter expression in tissues and adapt the therapeutic strategy. However, this is not performed due to its invasive character. Extracellular vesicles (EVs) are nanoparticles released by all cells of the organism. Their cargo (proteins, RNA and lipids) is frequently a dynamic fingerprint of the cell. The presence of EVs from different tissues in blood and urine allows for an easy access. The aim of this project is to evaluate if the amount of ABC transporters in EVs from blood and urine can be used to specifically predict the transporter expression at the tissues of origin under basal and induced conditions, as well as to predict in vivo drug pharmacokinetics. Following work packages (WP) are proposed: WP I: EVs as dynamic surrogate for ABC expression in vitro and ex vivo. I.I. Validation of an analytical protocol for the quantification of ABC transporters in EVs, I.II. Correlation between ABC expression in biopsies and in EVs from the same specimens, I.III. Correlation between expression of ABCs in EVs from primary cells and the expression and activity of ABCs in the cells of origin under basal and induced conditions. WP II: EVs as biomarker for drug pharmacokinetics. II.I. Optimization of the immunopurifica
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'International network on hiv-1 mother-to child transmission: developing integration of health care programmes, clinical, social and basic research' (1998-2002).

assistant: **Innovation**

The core group of the network is at the moment composed of representatives of Africa (6 countries), South-America (2 countries), Asia (3 countries), Canada, Europe (3 countries) and USA. A total of 30 groups, including representatives of the U.S.A. Center for disease control (CDC), National Institute of Health (NIH), and Elizabeth Glaser Paediatric AIDS Foundation (EGPAF), the Italian Institute Superior did Santa (ISS), and the French Agene National Recherché sure le SIDA (ANRS), have adhered to this initiative. To define the general objectives of the Network we propose to organize a workshop in May/June 2002. During the workshop the structure of the Network will be defined, as well as tropic-specific working groups and an executive committee created and their goals defined. To do so, during the workshop a series of lectures on relevant arguments will be provide, as well as large opportunities for discussion with invited scientific and health care experts. Thereafter, in the frame of an 24 months period, meetings of the topic-specific working groups and the executive committee should follow their achievements. Finally, to assess the activities of the Network a second workshop should take place. A written document will be produced to describe the network, its organization, structure, objectives, missions, and achievements.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Nucleation of Organic Crystals onto 2D materials' in the context of a Horizon 2020 call.

assistant: **Objectives**

The formation of crystalline solids from liquid-phase precursor is a central idea in materials chemistry. Organic crystal structures can be found in a large number of products, including food, explosives, pigments and pharmaceuticals. Control of molecular assembly is therefore a fundamental problem for both research and industry and it involves substantial scientific and economic challenges. For example, polymorphism is crucial for drug manufacturers because the crystal structure, morphology and size, can all affect the stability, efficacy and production cost of the drug. Therefore, it is essential to achieve a deep understanding on the molecular processes happening at the early stage of crystallization. Although important results have been obtained, our understanding on how a crystal of organic molecules nucleates on a surface is still poor. To go beyond state-of-the art we need techniques able to probe rare nucleation events with nanoscale resolution and very high sensitivity, providing direct insights on the structure of the nuclei and their interaction with the environment. The aim of this proposal is to use 2D crystals to open new horizons in the understanding of nucleation of organic crystals by using a multi-disciplinary approach, which combines chemical engineering, material chemistry, graphene physics and sensors technology. Graphene, a single layer of graphite, will allow preparing advanced surface templates and to perform nucleation experiments that would be impossible or too difficult to achieve with other templates. In particular, graphene will be used both as surface template and as sensor to probe nucleation events in real time. We will combine electrical and optical readouts to investigate molecular interactions during nucleation with chemical recognitio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Entanglement and Renormalisation for Quantum Fields' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Over the past fifteen years, the paradigm of quantum entanglement has revolutionised the understanding of strongly correlated lattice systems. Entanglement and closely related concepts originating from quantum information theory are optimally suited for quantifying and characterising quantum correlations and have therefore proven instrumental for the classification of the exotic phases discovered in condensed quantum matter. One groundbreaking development originating from this research is a novel class of variational many body wave functions known as tensor network states. Their explicit local structure and unique entanglement features make them very flexible and extremely powerful both as a numerical simulation method and as a theoretical tool.The goal of this proposal is to lift this “entanglement methodology” into the realm of quantum field theory. In high energy physics, the widespread interest in entanglement has only been triggered recently due to the intriguing connections between entanglement and the structure of spacetime that arise in black hole physics and quantum gravity. During the past few years, direct continuum limits of various tensor network ansätze have been formulated. However, the application thereof is largely unexplored territory and holds promising potential. This proposal formulates several advancements and developments for the theoretical and computational study of continuous quantum systems, gauge theories and exotic quantum phases, but also for establishing the intricate relation between entanglement, renormalisation and geometry in the context of the holographic principle. Ultimately, these developments will radically alter the way in which to approach some of the most challenging questions in physics, ranging from the simulation of cold ato
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how '6G-PATH: 6G Pilots and Trials Through Europe' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The path towards 6G is beginning now that 5G matured and is being deployed worldwide both publicly and privately. While 5G brought a step up in many fields, such as, performance and efficiency, more is always expected in terms of efficiency by the overall community and in terms of performance by industry and technology providers who want to further increase their offerings and products. Continuous demands for higher throughput, lower latency and more energy efficient communications needs to be supported by relevant use cases that can claim and demonstrate the needs for these requests.6G-PATH goal is to help foster the further development and integration of new and improved tools and products from EU companies with 5G/6G, while also measuring relevant KPIs and KVIs. To achieve this, 7 testbeds will be part of the project consortium, which will be used by 10 use cases spread across four key verticals: Health, Education, Smart Cities and Farming. Moreover, a relevant portion of the budget will be used for FSTP, where we envision the integration of 2 new Pilot Sites, extend the testbeds with 10 additional technologies, as well as 30 new Use Cases, through Open Calls, to further involve the community and obtain more metrics and outcomes.6G-PATH plans to work closely with other ongoing/starting Stream-B and Stream-C projects in a feedback loop, where the innovations that partners are achieving in other projects can be deployed and further tested by our pool of use cases and Open Calls, while sharing our results and outcomes to further cement the innovation being made.


**Keywords:** 6G, B5G, AIaaS, AAA, Closed Loop Coordination, education, energy efficient communications, farming, health, KPIs, KVIs, SaaS, slicing, smart cities, verticals
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Nuclear envelope proteins of Trypanosoma brucei', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The research objectives of this proposal are to functionally describe nuclear skeleton proteins of the important human parasite Trypanosoma brucei. Recent data, many of which come from the proposed host laboratory, have revealed two novel protein components of the nuclear envelope (NE) that seem to have similar function as lamins in metazoans. The applicant will attempt to explore the exact role of these proteins in epigenetic regulation of developmentally controlled genes (such as those encoding the coat antigens), nuclear architecture and chromatin organization. For this purpose, specific interactions of these proteins with chromatin, their phosphorylation status and its control as well as their 3D structure will be investigated. Parallel to this line of work, the applicant will also use various computational tools to search the available NE proteome for functional homologues of other nuclear skeleton components known in metazoans. The research is expected to yield important clues in the understanding of eukaryotic evolution and importantly also in the fight with trypanosomes and other closely related parasites such as Leishmania.The training objectives of this project are to further develop the candidate's already extensive knowledge of laboratory techniques and bioinformatics. Work on this project will especially enhance the applicant's computational biology, proteomics, imaging, and protein functional characterization skills. The multidisciplinary and highly collaborative nature of this project promises to greatly enhance the competences of the candidate going forward. The host laboratory and collaborators can provide all the facilities required and a strong training in molecular and cell biology. The newly acquired skills and experience will help the applicant to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Integrated process for seawater electrolysis using a PGM-free anion exchange membrane stack', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

ASTERISK proposes integrating seawater treatment and green hydrogen production using a Platinum Group Metal (PGM)-free anion exchange membrane (AEM) electrolyser. The consortium will work on developing AEM stack components compatible and stable under saline conditions, namely water oxidation and water reduction electrocatalysts, anion exchange ionomers and membranes, porous transport layers and electrical contacts. ASTERISK will incorporate a minimal seawater treatment step before the stack to remove biological, organic and suspended solids content with minimal energy requirements and operating costs, leaving the ions naturally present in seawater to enter the stack. The project will meet the challenging KPIs set by this call and significantly improve upon the degradation rate of <5% over 500h operation leveraging the current experience on materials and membranes design already developed in ongoing projects involving several ASTERISK partners. A final ASTERISK demo will achieve up to 100 gH2/h production on a 5 kWe stack operating for 2000h, to achieve the goal of reaching TRL 4 at project end.The technical work will be complemented with an eco-design process supported by an environmental and socio-economic analysis to guide the development of a low impact and circular designed AEM device maximising socio-economic benefits. A techno-economic and exploitation plan to move from laboratory scale single-cell to a multi-stack electrolyser will be studied to ensure a fast-track to commercialisation. If successful, ASTERISK will advance cost-effective and sustainable green hydrogen production and contribute to the European Union's long-term carbon neutrality and renewable energy leadership goals.


**Keywords:** Seawater electrolysis, water splitting catalyst, anion exchange m