RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Aerial Insights: facilitating access to aerial drone imagery services through novel and cost-effective data analytics solutions'.

assistant: **Objectives**

Aerial Insights is a software company based in Spain whose main focus is on the development and operation of imaging services with drones. Created in 2015 by a team of experienced and successful entrepreneurs, the company launched its new platform in 2016 to provide drone operators an affordable and innovative solution to extract drone imagery information from aerial data. Drones are becoming more and more popular and rapidly growing throughout the world. Today, they are used in multiple professional environments ranging from agriculture, insurance, mining industry to aerial photography and monitoring. According to recent PWC study, the expected business and services associated to drones will represent 127B USD globally. Among these services, drones equipped with cameras and other sensors (aerial photography) will play the most important role. Processing drone data with existing solutions is today cost-prohibitive. Data processing indeed requires expensive software and hardware as well expertise in multiple highly technical areas. Overall, we estimate an investment of 25K/year is required for physical resources, software and man hours to establish and provide services. Available at an average retail price €29,99 per map since 2016, Aerial Insights is based on a unique cloud platform and set of artificial intelligence algorithms where drone pilots can upload aerial raw imagery (step 1), select the outputs needed depending on the type of sensors onboard (step 2) and receive the relevant information on a secured online account within a few hours (step 3). This new approach is faster, cheaper and more reliable. For example, Aerial Insights reduces the timeframe required to diagnose and pinpoint faulty cells in a solar farm from 2-4 weeks (using traditional solutions) to 1-2
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Widefield Raman imaging probe for intraoperative margin assessment of cancers' under Horizon 2020.

assistant: **Concept**

Positive cancerous margins after surgery lead to an increased risk of progression and reduced disease free survival. Obtaining clear margins of cancerous lesions can be very challenging during surgery. Raman spectroscopy is a unique label-free optical technique based on inelastic light scattering that offers tissue ""optical biopsy"" at the molecular level. IMAGINE is a multidisciplinary approach that aims to develop the first widefield near-infrared (NIR) Raman imaging probe for intraoperative margin assessment. A new ultra-high sensitive InGaAs focal plane array (FPA) camera integrated with a novel combination of band-pass filters will be integrated to selectively probe the biomolecular constituents of tissues in the high-wavenumber range (i.e., 2800-3600 cm-1) providing a new endogenous biomolecular contrast mechanism for visualisation of resection margins during cancer surgery. A prototype will be developed and applied ex vivo on excised tissues from colorectal cancer patients. Histopathology will serve as gold standard and the sensitivity, specificy, receiver operating characteristics (ROCs), tumour contrast, and potential clinical/surgical impact will be evaluated. The new optical bioimaging modality proposed here constitutes a simple non-invasive cost-effective and broadly applicable technique for margin assessment of cancers compatible with in vivo laparoscopic settings. This translationally driven project fosters multidisciplinary research involving bioengineering, optical engineering and clinical research and has the support of a strong international industrial secondment. IMAGINE will enhance the mobility and innovative potential of the applicant and open new avenues in cancer surgery, which will strengthen the scientific excellence in Europe and ultimately b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Development of Foamy Virus Vectors for Gene Replacement in Chronic Granulomatous Disease' (FOAMYCGD) under Sixth Framework.

assistant: **Objectives**

The current proposal is designed to test whether a retroviral vector developed from the Foamy virus (FV) can be used as a therapeutic vehicle to correct a human genetic disorder that affects the cells of the haematopoietic system. FV vectors are developed from the non-pathogenic foamy retrovirus and have been shown to transduce haematopoietic stem cells (HSC) of both murine and human origin. FV-based vectors show promise for therapeutic gene delivery into HSC and offer an alternative technology to the existing retro and lenti vector systems. As a next step in FV vector development, we plan the genetic correction of Chronic Granulomatous Disease (CGD), a disorder that results from the absence of NADPH-oxidase in the phagocytes of the peripheral blood and impaired killing of ingested microorganisms. Affected patients present with severe bacterial and fungal infections, which appear early on in life and may be fatal.The commonest form of CGD is X-linked and results from the absence of the gp91phox subunit of NA DPH. The relative knockout mouse model (X-CGD) closely mimics the human disease phenotype and will be used in this study. Preliminary studies with the X-CGD mouse model will aim at optimising transduction conditions for HSC gene transfer using reporter genes driven by constitutive and tissue-specific promoters. Following these studies, we will use the optimised conditions to transfer the therapeutic gene into the HSC of the X-CGD animals and will assay disease correction by standard assays. Finally, we will target CD34+ cells from individuals with CGD and evidence for disease correction will be obtained from both in vitro assays and after BMT into NOD/SCID mice. The experiments as described will provide us with the necessary data in a pre-clinical model of a human d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Bringing molecular photomagnets to light - achieving magnets through visible light excitation at room temperature' (LUX-INVENTA) targeting Horizon Europe.

assistant: **Abstract**

Visible light provided by the Sun is the cleanest energy source one could ever imagine. Harvesting it is crucial for further development of science and technology as well as for reducing the ecological footprint of humanity. The efficient use of the visible spectrum of the Sun can take many forms and the direct photoexcitation of molecules resulting in a dramatic magnetization change - the so called photomagnetic effect - is one of them. In other words, sunlight photons could write, read and erase magnetic states of photomagnets. Photomagnets can be designed and prepared via a bottom-up modular approach using low-energy preparation methods developed by coordination, organometallic chemistry, supramolecular chemistry and crystal engineering with the support from physical and computational sciences. Photomagnets belong to the class of smart multifunctional molecular materials that become paramagnetic, ferromagnetic or simply change their magnetic properties upon illumination - a feature that is hardly accessible in conventional magnetic solids - metal alloys and oxides. Currently known photomagnets are merely laboratory curiosities due to extremely low operation temperatures below the boiling point of nitrogen (-196?C). Hence, the overarching goal of LUX-INVENTA is the discovery of room temperature (RT) photomagnets that would show light-induced ON/OFF ferromagnetic switching under normal conditions. This goal will be pursued alongside the deep understanding of the processes occurring during the absorption of a photon by photomagnetic chromophores - the molecular components responsible for the photomagnetic effect. The proposed research focuses on (i) the design and synthesis of novel photomagnetic chromophores, (ii) investigation of the mechanism of the photomagnetic swi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Towards the development of a hydRogen valley demonstratIng applications in an intEgRated EcoSystem in Greece'.

assistant: **Concept**

TRIĒRĒS is Greece’s first Hydrogen Valley brings together business, knowledge and regional interests. The TRIĒRĒS Valley starts as a small scale Valley but has a tremendous upward perspective over a large part of the Balkans, South-Eastern Europe and the wider area of Eastern Mediterranean. The Valley will be built around the nucleus of MOH’s Corinth Refinery complex. From a business perspective the project has strong transeuropean interest as 80% of the refinery sales are generated outside of Greece, rendering it internationally oriented by default. Creating and building a Valley using the refinery as Hydrogen generator accelerates the transition, with an annual production of 2,410 tons of Green Hydrogen that will be utilised in the production of low and no Carbon footprint energy and industrial products and will be injected in the natural gas grid creating a Hydrogen Backbone of full EU interest. High visibility actions in mobility will include one (1) short-sea ferry ship, three (3) public transport buses, and at least (two) 2 cars. Knowledge and innovations are spurred through the intensive collaboration with knowledge institutes and SME’s. The participation of the local and regional governments assures the component of public acceptance, understanding and advocacy, generating interest to many parties supporting regional economic growth. The learnings from HEAVENN and WIGA P&G Valleys will be replicated with the specific knowledge of the Greek and broader connected geographies. TRIĒRĒS entails an investment of 115 mil EUR (initially by project partners) up to 408 million EUR (potential direct/indirect leverage of investments). Several thousand people will be employed during the realisation of the valley project, which will promote new skills development. The consort
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'NEurobehavioural predictiVE and peRsonalised Modelling of depressIve symptoms duriNg primary somatic Diseases with ICT-enabled self-management procedures' (NEVERMIND) targeting Horizon 2020.

assistant: **Abstract**

Personal health systems for the management of chronic diseases have seen giant leaps in development over recent years. These systems offer vital sign monitoring and therapy delivery at home, focusing on the primary physical disease conditions. However, they do not provide support for early mood assessment or psychological treatment and lack a real-time comprehensive assessment of the patient’s mental status. Depression is the third leading contributor to global diseases, and depressive mood state is also considered to be strictly related to the onset or worsening of a severe primary somatic disease. Indeed effective preventive medicine related to the onset of depressive symptoms as a comorbidity and worsening factor of psychosomatic diseases such as myocardial infarction, leg-amputation, cancer, and kidney failure is lacking. NEVERMIND sets out to empower people who suffer from symptoms of depression related to a serious somatic disease by placing them at the center of their mental healthcare. Equipped with just a smartphone and a lightweight sensitized shirt, patients seeking care and treatment for their mental illnesses interact with these devices that collect data about their mental and physical health, to then get effective feedback. Lifestyle factors, i.e. diet, physical activity and sleep hygiene, play a significant mediating role in the development, progression and treatment of depression, and in NEVERMIND will be monitored by a real-time Decision Support System running locally on the patient’s smartphone, predicting the severity and onset of depressive symptoms, by processing physiological data, body movement, speech, and the recurrence of social interactions. The data will trigger a response encouraging the patient to conduct or alter activities or lifestyle to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Design and evaluation of new polymer electro-optic modulators and switches' (1998-2002), addressing dissemination and exploitation.

assistant: **Impact**

The project aims at producing new designed polarization insensitive optical modulators and switches based on polymeric 2nd order nonlinear materials for high speed applications. A new compact design of the monolithic electro-optic Mach-Zehnder interferometer will be introduced and used to build a polarization insensitive, low-loss, fast amplitude modulator with possible integration with lasers. The switching voltage, i.e. the voltage it takes to change the output signal from its maximum to its minimum value, for the device is an issue that can be improved with this more compact design. Along with the Mach-Zehnder modulator an asymmetric Y-branch digital optical modulator will be designed, fabricated, evaluated and compared to interferometric modulators. State of the art materials for telecommunication wavelengths will be used in the implementation of these devices. All these new devices will be fully characterized with respect to efficiency, bandwidth and insertion losses. Since it is of great importance to have better integrable electro-optic components for optical communications in order to improve the speed and costs for signal processing, the research on these issues is crucial. The high speed, low loss and low crosstalk are the main aspects that will be addressed on during this project. These features are inferred by the small size of this device and compact design as well as the efficiency of the materials. This project will open up the opportunity for the candidate, after having developed his skills on fabrication and characterization of monolithic devices, to be working on applications in the field of electro-optics. This project will therefore broaden the candidates competence and skills regarding nonlinear optics and the applicant will gain knowledge of a numb
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Laser and Ultrasound Co-Analyzer for thyroid nodules' (LUCA).

assistant: **Innovation**

This is a trans-disciplinary project that joins endocrinologists (“end-users”), radiologists (“end-users”), physicists who areexperts in medical photonics, engineers who are experts in photonics and ultrasonics and the industry to work towards aconcentrated goal - to produce a novel, point-of-care, low-cost, screening device that combines two photonics systems(near-infrared diffuse correlation spectroscopy (DCS) and time-resolved spectroscopy (TRS)) with a multi-modal ultrasound(US) system and a probe that enables multi-modal data acquisition for the screening of thyroid nodules (TN) for thyroidcancer (TC). TN are a common pathology having a prevalence of palpable nodules around 5% in women and 1% in men,that increases to 19-76% with the use of neck US. In screening thyroid nodules, to exclude thyroid cancer which occurs in5-15% of TN, the first step is the US followed by fine needle aspiration biopsy (FNAB) of suspicious nodules. The sensitivityand specificity of this process in thyroid cancer are limited, with a large number of non-diagnostic and false positive resultsthat lead to unnecessary surgeries. A reduction in the number of surgeries with a point-of-care diagnostic procedure wouldhave an important socio-economic impact, diminishing the number of thyroidectomies and the associated comorbidities. Thisimplies savings of millions of euros per year. Evidence shows that multi-modal approaches that include hemodynamicinformation leads to better specificity while each modality on its own fails. We hypothesize that a new optical-ultrasoundprobe and integrated system enabled by the development of novel, key enabling photonic components and sub-systems toprovide synergetic information on tissue morphology, composition and function will have a large impact in this field.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Expanding the Properties of Artificial Spider Silk' in the context of a Horizon Europe call.

assistant: **Objectives**

Spider silk is a material with remarkable biological and mechanical properties. Unfortunately, the cannibalistic nature of spiders makes it impossible to harvest natural silk at large quantities, whereas artificial silk production has historically suffered from poor quality, low yields, and environmentally harmful protocols. Overcoming these limitations, Prof. Anna Rising (host) has recently developed a biomimetic spinning setup for generating high quality artificial silk fibres that uses water as the sole solvent and scales volume for economically feasible mass-production. Although remarkable, the fibres generated still require improved mechanical and electromagnetic properties to achieve their full potential in the envisioned biomedical and soft electronics applications. By combining the host’s expertise in protein biochemistry and biotechnology with my (Dr. Greco, fellow) skills in mechanical and materials engineering, EPASS aims to improve the mechanical and electromagnetic properties of artificial silk fibres by spinning fibres from protein solutions containing carbon nanotubes and magnetic nanoparticles. After establishing an optimized spinning protocol for the introduction of nanomaterials, a new generation of modified silk fibres will be spun and analysed morphologically, mechanically and electromagnetically, delivering a novel strategy for generating silk fibres with custom-made properties that are highly needed in the area of soft electronics. With additional expertise gained from a secondment and short-term visit, EPASS will create a strong foundation for state-of-the-art research and extensive knowledge sharing between researchers and organisations.In summary, EPASS will integrate novel methodologies to create a new generation of scalable green materials wit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Using periodic orbits to quantitatively describe and control 3D fluid turbulence.' (PERTURB).

assistant: **Concept**

Fluid turbulence is of key importance in engineering: it controls the drag on aircraft, is a major contributor to unwanted energy dissipation in pipelines, yet mixing of chemicals relies on it. Despite its importance, our understanding of turbulence is incomplete. Controlling turbulent flows, which would lead to significant efficiencies for industrial applications, remains a challenge. The recent identification of unstable non-chaotic solutions of the Navier-Stokes equations suggests a promising framework to study the phenomenon. Here turbulence is viewed as a chaotic walk through a forest of exact solutions in the infinite-dimensional state space of the flow equations. While this dynamical systems approach helps rationalizing features of the transition to turbulence, it has so far failed to deliver on the promise it carried since the identification of deterministic chaos in the mid 20th century: To provide a predictive description of turbulence in terms of exact solutions and to act as a rational basis for controlling flows. The major road block to fulfilling the promise is that we are missing tools to identify enough dynamically relevant exact solutions. These are time-periodic non-chaotic solutions that allow us to express statistical properties of turbulence as a weighted average over periodic orbits. Owing to the exponential error amplification in a chaotic system, periodic obits for 3D flows have been almost inaccessible. Instead, research has focused on isolated steady solutions that resemble features of the flow but are dynamically less informative. We will remove the road block and construct extensive libraries of periodic orbits for two canonical 3D flows, turbulent convection and channel flow. By combining variational methods with machine learning tools we wi