RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Carbon balance estimates and resource management support with data from project networks implemented art european continental scale' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

Problems to be solvedCARBODATA is a project designed to exploit and to make widely available the results of the EU funded research projects such as EUROFLUX, MEDEFLU and CANIF concerning carbon fluxes and carbon stocks of European forests. The EUROFLUX and MEDEFLU Programmes have established 25 sites in Europe with continuous monitoring of carbon, water, and energy exchanges in forests. Methods used have been standardised and quality controlled in terms of data acquisition and the suite of important variables measured. An additional suite of data on nitrogen and carbon processes, especially considering the links between soils and vegetation processes, has been assembled by the project CANIF and will be available through CARBODATA. Additionally, it will assemble a CO2 database at European continental scale and with inverse modelling produce continental scale maps of CO2 exchange between the vegetated surface and the atmosphere.Scientific objectives and approachCARBODATA specific objectives are:i) to create an on-line data centre where it is possible to retrieve information related to the carbon cycle for a wide range of ecosystems and locations;(ii) to provide on-line estimates of day by day changes in the carbon sink and source strengths at various sites where highly integrated ecosystem studies are ongoing;(iii) to distribute on-line data for validation of remote sensing products;(iv) to provide summaries (products and tools) in the form of models on-line that may be applied in carbon balance analyses;(v) to support development of up-scaling efforts by synthesising results from carbon balance studies, and thereby to build an interface between remote sensing products and the community examining ways to influence the carbon cycle;(vi) to provide European maps of fluxes o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Silicon Treatment ON Exterior Wood' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

STONE Wood project is designed to improve an already existing environmental-friendly patented product for wood protection and restoration. It can be used in many applications where this material is essential for its characteristics (as architecture or marine use).The product is an outstanding innovation able to guarantee 10 to 15 years of protection (10 times more than traditional coatings and 4 times more than our direct competitors) against biodegradation and weathering, thanks to a new composition which uses a potassium silicate compound and an emulsion of polymerizable alkoxy silane. It is applied through 2 solutions totally biocide and VOCs free. During the polymerization reaction, it absorbs atmospheric CO2 contributing to lower the greenhouse gas levels. The improvement objectives will regard (a) customization to access to new markets, (b) an increase of its protective performance, (c) an optimization of the industrial application and (d) a reduction of production costs. We are aiming at both end users and wood transformation industry that will be able, thanks to the remarkable performances of our product, to save time and money for the protection of their materials. The feasibility study will provide an assessment of the viability of our established technical objectives and a marketing analysis to find the best entry strategy to disseminate and exploit the results. Special care will be put on the evaluation of eventually existing related patents and to protect our unique composition. STONE Wood will be able to greatly increase our business opportunities and boost the whole European wood sector introducing an exceptional technological advantage over direct competitors.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Inclusive open schooling through engaging and future-oriented science', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Science education needs to make students more scientifically literate and encourage larger numbers to take up science careers. Open schooling approaches can make science more authentic but tend to be adopted only as extra-curricular activities, in a minority of schools or are limited to gifted and talented students. CONNECT is an inclusive, sustainable model for enabling more secondary schools to adopt open schooling by embedding science-action projects in the core curriculum, using participatory science approaches with universities and enterprises. A science-action makes science more relevant to studentsOur age is profoundly shaped by science and technology innovations. Societies must become more scientifically literate to be able to make evidence-based decisions and sustain themselves in our highly competitive world. One solution that has been proposed for increasing students' aspirations in science is to open up school through partnerships and family involvement.To make open schooling inclusive and widespread in science education, we believe 3 questions need to be addressed: Q1. How can open schooling increase the value and priority of partnership activities and reduce the barriers to entry so more schools are willing and able to adopt them ? Q2. How can open schooling facilitate the interaction between all partners (science professionals, teachers, students and their families) to result in effective learning experiences linked to R&I?Q3. How can open schooling make science careers more inclusive by giving disadvantaged students more experience and insight into professional STEM jobs, supported by professionals and their families? CONNECT is an inclusive, sustainable model for enabling more secondary schools to adopt open schooling by embedding science-action gamific
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'The Low Energy Limit of String Theory and the Observable World' (OBSERVABLESTRING).

assistant: **Innovation**

The long-standing challenge of string theory, confronting the real world, has become more pressing and at the same time tangible in view of the upcoming LHC. Since the low energy limit of the theory is the main stage where predictions can be compared with experimental data, the goal of this project is to develop a new unified framework to formulate, compute and analyze this limit and its phenomenology. Understanding the low energy limit of string theory at the level where it can be confronted with precision experiments requires two key elements. On one hand one must obtain the full low energy Lagrangians resulting from compactifications from ten to four dimensions. On the other hand, one must analyze the couplings of quarks and leptons, represented by open strings attached to branes.  Attempts to construct four-dimensional effective theories have focused in the past on a particular class of six-dimensional spaces, but my work in the last few years has shown that realistic solutions arise from manifolds whose differential properties are actually much weaker and that these compactifications have an elegant reformulation in terms of a generalized version of Riemannian geometry. I plan to use the formalism of generalized geometry to obtain the full tree level, perturbative and non-perturbative corrections to the 4D LEEL resulting from compactifications on these manifolds, and to study their phenomenology. Obtaining the full LEEL is the key step towards understanding if the world as we see it today comes from a string theory compactification: only full knowledge of the Lagrangian allows us to determine in detail how these manifolds lead to theories having 4D isolated vacua with a tiny positive cosmological constant, and support branes whose gauge theory spectrum and coupling
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Data-Driven Agent-Based Models of Investors with Machine Learning' (DataABM) under Horizon Europe.

assistant: **Objectives**

Image recognition or self-driving cars are just a few among many applications of machine learning (ML) methods. Given that we can train a cobot to mimic human behaviour, why not train a computer to mimic and simulate investor behaviour in stock markets? This would not only improve understanding about investor decision making and their interaction, but provide effective tools to predict investor behaviour on the microscopic level and simulate stock markets on the macroscopic level. The main objective is to create a data-driven Agent-Based Model (ABM), where agents' behaviour is governed by ML. Such models need appropriate data to be trained, which is possible thanks to a unique, big data set on investor level data accessible through the host. The objectives are: i) framework for data-driven ABM, ii) interpretable ML for ABM, iii) verification of the interpretability of data-driven ABMs using synthetic data, iv) training the data-driven ABMs using actual shareholder registration data, and finally v) analysis of investors decision-making mechanism. The objectives will be reached by using ML methods that achieve intrinsic interpretability with and without deep supervised learning. This research requires: a) strong numerical skills and experience with simulations, b) computer infrastructure allowing to carry out largescale numerical analysis for which the fellow and the host have complementary experience. The results will bring us closer to understanding the behavioural mechanism of market participants. The project does not just gain understanding, but introduces a data-driven approach to more realistic agent-based modelling, which is completely new. The outcome should focus the attention of regulators and policy makers, who are often unable to realistically predict the effe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Balancing Adaptive Cooperative Technology' (BalancingACT), addressing dissemination and exploitation.

assistant: **Impact**

Balance impairment affects a large proportion of the global population, as a symptom of many neurological diseases and a consequence of advanced age. Methods to improve balance through rehabilitation or assistive devices are effective but are limited by the availability of physiotherapists or by the strength and agility of the patient. While robotic assistive devices could augment mobility, extensive training is often necessary to receive the full benefits. BalancingACT will tackle this bottleneck by investigating methods to facilitate co-adaptation of user and balance assistance, providing personalized assistance directly targeting balance outcomes. The GyBAR, a gyroscopic backpack, has improved standing and walking balance for both healthy and stroke populations, but could benefit from targeted user training. BalancingACT will address three main aspects of human-robot co-adaptation. I will first examine existing datasets from healthy and patient populations to determine which balance metrics explain differences between populations, providing a measure to gauge and optimize human-robot co-adaptation. I will then probe methods to improve motor learning for a healthy population in a challenging task, i.e., walking along a narrow beam. Exploration, driven by the individual or by the device, is a vital component of early learning. I will conduct two experiments, one to understand how self-guided exploration affects learning and one using human-in-the-loop optimization, a method to customize assistance by directly estimating the user’s response to a variety of candidate controllers, to determine the benefits of device-led exploration. This algorithm has previously elicited positive learning effects in exoskeletons and can also provide insight into the third aspect of co-ada
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Functional studies on components of human nuclear domains which contain the acute promyelocytic leukaemia proto-oncoprotein pml'.

assistant: **Concept**

Research objectives and content Acute promyelocytic leukaemia (APL) arises following a reciprocal translocation t(15;17) that fuses PML with retinoic acid receptor alpha (RARA). The PML-RARA fusion protein targets and disrupts nuclear multiprotein complexes called PODs, ND10 or NBs, a process which is associated with a block in myeloid differentiation leading to APL. The normal functions of PML NBs are presently unknown although to date twelve proteins have been identified as being part of this multi-protein nuclear complex. The proposed project is to identify further PML NB components using molecular and genetic techniques with particular emphasis on one recently identified component known as Ret Finger Protein (RFP). RFP, like PML, is oncogenic as part of a fusion protein, contains similar protein sequence motifs/domains and transiently associates with PML NBs in vivo.. The proposed studies will allow new insights into the normal functional roles of PML NBs which help our understanding of the molecular events which lead to APL.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Economic DLC coatings for dry sheet metal working'.

assistant: **Concept**

Productivity in sheet metal working suffers from the need for lubrication. Reasons are high costs for purchasing the lubricating agents and machines, disposing the waste oil and washing of the formed parts. In working of stainless steel and aluminium lifetime of the forming tools is mainly limited by cold welding of the formed metals. Thin hard coating systems based on diamond like carbon (DLC) have already shown a high potential for lubrication reduced sheet metal working in forming tests. For use in production lines at SMEs it is necessary to further develop these coating systems by using inexpensive deposition processes. As conventional coating deposition processes under high vacuum conditions suffer from high costs, it is an important task is to optimise coatings from a fine vacuum process, which have advantages concerning coating and equipment costs, the potential for process up-scaling and increased productivity. Forming processes to be investigated are deep drawing with a high forming degree and stamping/cutting of above mentioned materials. Aim of this project is to develop suitable coating systems, optimise their properties and proof satisfying lifetime in laboratory and production tests in dry forming. Rules are to be worked out for future industrial application of this coating technology in sheet metal forming.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The Molecular Basis of Mitochondrial Disease: Elucidating the Function of the Mitochondrial Inner Membrane Protein MPV17' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Mitochondria contain their own DNA (mtDNA), which contributes essential components of the energy generating system of the organelle. Because mtDNA requires many nuclear gene products for its maintenance and expression, nuclear gene defects can lead to mtDNA loss. MPV17 is one such gene, pathological mutations in MPV17 were identified by the researcher as a cause of mtDNA loss, yet the function of the protein remains obscure. The primary aim of the project is to elucidate the function of MPV17p, in order to understand how mutations in this gene cause mtDNA loss and human pathology. Specific aims are: i) to affinity-purify tagged versions of MPV17p from human cultured cells with the aim of identifying partner proteins. ii) To characterize the protein components of the different molecular weight complexes that contain MPV17p, using native electrophoresis. iii) To determine the effects of modulating the expression of MPV17p upon mitochondrial function and mtDNA integrity and stability in human cells, using an inducible expression system. iv) To harvest correctly folded and functional recombinant MPV17p from bacterial membranes for in vitro experiments and structural biology studies. The new information is expected to provide further insights into mitochondrial diseases and to yield fundamental knowledge of the mitochondrion. It is anticipated that the advance in knowledge will have implications for disorders of mitochondrial DNA maintenance in general, not only those related directly to mutations in MPV17.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Interactive Devices for Efficiency in Automotive  with Increased Reliability and Safety'.

assistant: **Objectives**

The overall objective of IDEAS “Interactive Power Devices for Efficiency in Automotive  with Increased Reliability and Safety”, - is to develop advanced packaging for power supply components and new generation memory systems  having application on Electric and ICE propelled vehicles and aiming at covering complementary aspects which haven’t yet addressed into the main running ENIAC and ARTEMIS Automotive projects.One of the main challenges of the introduction of the electronic systems in the automotive ,in particular for electrified vehicles, is the reliability and the availability of the power supply systems, which must assure the functionality to all the subsystems (See Figure 1). In this context the packaging of the supply systems play a crucial role and efforts needs to be dedicated to improve the thermal performances of them. On the other side the control systems which relies on multi-core microcontroller and complex software architectures, are requiring increasingly stringent constraints from the memory devices which needs to be designed for very high bandwidth, speed and reliability.  The key objective is the enhancement of the power train platform to ensure the thermal performance and the reliability requirements in particular vs. thermal & power cycles  and life time.Another key objective is to develop a new memory system specifically designed for the aggressive requirements as required for the control systems of advanced ICE or Electrically propelled vehicles. Main requirements will be a very high bandwidth to ensure a fast access for real-time operation with concurrent access to allow the usage of multi-core processor, coupled with very high safety requirements, and additional legacy interface to permit the In-System Programming, and a very high robustness fo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Visualizing tolerance induction: behavior and function of regulatory T cells during the establishment of materno/fetal tolerance' (VISTO).

assistant: **Concept**

The presence of foreign (allogenic) tissue in a host yields an immune response with the goal to destroy the tissue. During pregnancy, however, the semiallogenic fetus is allowed to grow within the maternal uterus. This ‘immunological paradox of pregnancy’ has received much attention because of its therapeutic implications in organ transplantation and autoimmune diseases.While it has recently been established that regulatory T cells are essential in establishing tolerogenic conditions during pregnancy, little is known about where and when T regulatory act.I will characterize, using transgenic mouse lines and intra-vital two photon microscopy, the spatio-temporal characteristics of T regulatory cell recruitment at the materno/fetal interface. I will analyze the dynamics of cellular interactions between T regulatory cells with other immune system cells under physiological conditions and in a mouse model of spontaneous abortion. Finally, I will use a candidate gene approach to reveal similarities between molecular mechanisms of materno/fetal tolerance and tumor immune escape.A better understanding of the mechanisms leading to materno/fetal tolerance will have therapeutic implications for the treatment of patients with recurrent spontaneous abortion and pre-eclampsia, for organ transplantation and for autoimmune diseases. Moreover, the interdisciplinary comparison of similarities between materno/fetal tolerance and tumor immune escape will provide novel experimental approaches for tumor immuno-therapy.