RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Seizure Cluster Relief through Smart Therapeutic Management' (CLUSTREL) targeting Horizon Europe.

assistant: **Abstract**

Epileptic seizures significantly impair patients' quality of life and autonomy. Despite recent advancements in wearable monitoring of brain activity, patients still struggle with seizures management and their pharmacological mitigation. CLUSTREL addresses this problem. It will develop a smart, non-invasive oral device for on-demand delivery of rescue medication to treat epileptic seizure clusters, a critical unmet need of ~15 million patients with drug-resistant epilepsy worldwide. The technology uses a patented, graphene-based system that releases medication within minutes of seizure onset, triggered manually or automatically by an existing external EEG sensor.The project's objective is to advance this technology from a lab-validated proof-of-concept (TRL 4) to a clinically relevant prototype demonstrated in a relevant environment (TRL 6).This will be achieved by:- Optimizing the graphene-drug pharmaceutical formulation for stability and rapid mucosal absorption;- Engineering a miniaturized, biocompatible, and user-friendly prototype for use in animal models;- Conducting comprehensive preclinical validation of the device's safety and efficacy in vitro, in rodent models of epilepsy, and in large animal models;- Establishing a spin-off company to manage IP, define the regulatory pathway, and secure strategic partnerships for commercialization.CLUSTREL aligns perfectly with EIC's TRANSITION vision, as it addresses a significant healthcare challenge by translating a breakthrough European technology into a market-ready medical device. It promises to reduce hospitalizations, lower healthcare costs, and significantly improve patient autonomy and quality of life, strengthening Europe's leadership in MedTech innovation.


**Keywords:** epilepsy, drug-release, graphene, seizure
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The molecular basis of pancreatic beta cell replication' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

A fundamental challenge of pancreas biology is to understand and manipulate the determinants of beta cell mass. The homeostatic maintenance of adult beta cell mass relies largely on replication of differentiated beta cells, but the triggers and signaling pathways involved remain poorly understood. Here I propose to investigate the physiological and molecular mechanisms that control beta cell replication. First, novel transgenic mouse tools will be used to isolate live replicating beta cells and to examine the genetic program of beta cell replication in vivo. Information gained will provide insights into the molecular biology of cell division in vivo. Additionally, these experiments will address critical unresolved questions in beta cell biology, for example whether duplication involves transient dedifferentiation. Second, genetic and pharmacologic tools will be used to dissect the signaling pathways controlling the entry of beta cells to the cell division cycle, with emphasis on the roles of glucose and insulin, the key physiological input and output of beta cells. The expected outcome of these studies is a detailed molecular understanding of the homeostatic maintenance of beta cell mass, describing how beta cell function is linked to beta cell number in vivo. This may suggest new targets and concepts for pharmacologic intervention, towards the development of regenerative therapy strategies in diabetes. More generally, the experiments will shed light on one of the greatest mysteries of developmental biology, namely how organs achieve and maintain their correct size. A fundamental challenge of pancreas biology is to understand and manipulate the determinants of beta cell mass. The homeostatic maintenance of adult beta cell mass relies largely on replication of differenti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'The effect of Fatigue on Muscle Movement Accuracy and Smoothness and exercise-induced injury' (FMMASI).

assistant: **Innovation**

Fatigue is a multifaceted phenomenon that has been reported as having a detrimental effect on movement quality. Previous studies have predominantly focused on either the effect of fatigue on gross muscle function or basic proprioception and often used specific clinical populations e.g. brain damaged patients.  This Fellowship proposal aims to further the understanding of how fatigue effects complex movement within a healthy high skilled population.  With this fellowship a novel approach is to be developed that combines cutting edge kinematic analysis with multidisciplinary methods (physiology, biomechanics and psychology) to investigate the mechanisms underlying complex multi-muscle performance as seen in activities such as dance.  We will measure postural sway and muscle movement smoothness and accuracy though force plate, EMG and 3-d analysis under individual and multiple fatigue-inducing conditions on three dance populations of varying skill levels. This will lead to a series of intervention studies to see if the deterioration of movement quality can be negated or slowed. Fatigue has been cited as one of the main causes of musculoskeletal injury within a wide range of healthy and diseased populations. Within dance this has resulted in a high incidence of injury within the lower limbs especially during the landing phase of jumping. The fellow will examine the efficacy of current injury screening protocols in relation to fatigued movement prior to the development of novel screening tools that better predict the tendency of poor limb alignment within fatigued states. With this fellowship we will carry also out a list of dissemination activities engaging with the European and international dance and medical communities. The Fellowship, with the help targeted training act
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Towards new frontiers for distributed environmental monitoring based on an ecosystem of plant seed-like soft robots' to be submitted under Horizon 2020.

assistant: **Abstract**

I-Seed aims at developing a new generation of self-deployable and biodegradable soft miniaturized robots, inspired by the morphology and dispersion abilities of plant seeds, to perform a low-cost, environmentally responsible, in-situ detection of key environmental parameters in air and topsoil. Seeds dispersal strategies are driven by the spontaneous, often reversible, anisotropic deformation of their tissues upon swelling or drying of cell walls, and do not require any control or internal energy supply.Following a bioinspired design, these skills will be implemented into seed-like robots by using multi-functional biodegradable materials and natural morphological features, which endow them with the ability to fly and disperse via natural vector-mediated diffusion in air, or to respond to humidity variations to move on terrain surface and self-penetrate in topsoil. Sensing will be based on diffusion, absorption, and structural changes of parts of the robots made from sensor materials with a chemical transduction mechanism and fluorescence-based optical readout. Recordings of temperature, humidity, CO2 and mercury (Hg2+) will be executed at air-soil interface. Deployment of the I-Seed robots and reading of the acquired measurements will be performed using drones. Seed-drone communication will rely on optical signaling and fluorescence based on Light Detection and Ranging technology (fLiDAR), and using photonic ""tags"" to impart different type of sensors and robots a unique response. Algorithms will be developed such that drones can map the robots in air and on the ground.By merging bioinspired soft robotics, material science, nanocomposite technologies, and environmental science, I-Seed will address the specific challenge by building a radically new dynamic scenario for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Co-modal Airport' to be submitted under Seventh Framework.

assistant: **Abstract**

The ModAir project aims at designing and setting up a mode-overlapping forum, where representatives from the air, rail and urban transport as well as any other relevant actor will contribute to the development and improvement of co-modality and intermodality for passengers in European airports.The interconnectivity at European airports is often still limited to urban transport, with in particular very few high-speed train stations. Some of the existing intermodal links do not fully meet the passengers’ expectations, leading to low usage.ModAir will build on the projects already funded by the European Commission to give a clear view of the current state of intermodality and co-modality in the Euro-pean airports, deliver a roadmap for future research and provide the European Un-ion with a structured group of experts able to help choose the best ways of imple-menting the connectivity of airports with other transport modes.Through cooperation between air and rail stakeholders, as well as intermodality and transport specialists, ModAir will be able to contribute to the preparation of future EU research and technological development policy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Rethinking Secularity in the light of Contemporary Religious Revival: Female Religious Agency'.

assistant: **Innovation**

The research project, embedded within the interdisciplinary field of Women's Studies, seeks to account for the engagement of women in contemporary religious (fundamentalist) revival movements, against the background of following observations: (1) an increase in religious identifications and subsequent challenges to the secular status quo, (2) the great participation of women in this religious revival, and (3) an emphasis within such movements on moral issues of family, sexuality and kinship, including strict positions on gender arrangements and women¿s roles and behavior. The project consists of a first theoretical part exploring religious revival and fundamentalism and addressing debates on religion within Women¿s Studies, on the status of secularisation theories within Sociology of Religion and on the structure-agency question within Social Sciences in general. For this purpose, innovative concepts such as `religious modernities¿ and `(female) religious agency¿ will be used and further developed. A second empirical part focuses on the analysis of original data (life-stories of women involved in religious fundamentalist movements) and complementary data gathering. Both the theoretical questions and the empirical case-studies of the relationship between women, religious (fundamentalist) revival and contemporary society are specifically located in a European context (empirical case-studies in Russia, Italy and the Netherlands). The project is based on a very recently completed doctoral dissertation, which the examination committee praised for its excellence, and seeks to consolidate (through the publication of a book and scientific articles) and further pursue its findings. The mobility action would enable an intensive investigation of the innovative concepts religious m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Training Multidisciplinary scientists for Tissue Engineering and Regenerative Medicine', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

MultiTERM is a training network providing multidisciplinary training for 13 early stage scientists in 5 host institutes that will deliver a number of excellently trained, highly employable scientists for companies and academia in the field of tissue engineering and regenerative medicine (TERM). The aging population of the EU requires the development of new treatment strategies for diseased, defective, or damaged tissues. Since donor material is often not available, artificial tissue needs to be developed for these purposes. Therefore, smart materials that can be used to replace and repair tissues should be developed. With better tissue engineering possibilities becoming available, improved methods to visualise the fate and effects of these implants are essential and need to be examined. TERM is a multidisciplinary field where scientists need to cut across traditional fields of study. They need to understand completely different aspects - ranging from material choice, cell biology, to clinical translation - to successfully design and clinically implement engineered tissue. Unfortunately, such scientists are scarce, because such TERM-specific interdisciplinary training is missing. To fill the gap that currently exists, the MultiTERM Network will provide early stage researchers with individual and centralized training in key elements of TERM: biomaterials, cell biology, bioreactors, animal modeling, clinical and industrial translation. The MultiTERM Partners, including the industrial partner, are recognized leaders in their fields - ensuring state-of-the-art training - with highly complementary, cross-sectorial skills, and have extensive prior FP experience, assuring achievement of this goal. During their training, the early stage scientists will develop new materials and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Production of hydrogen rich gas by biomass gasification: application to small scale, fuel cell electricity generation in rural areas' (1994-1998).

assistant: **Innovation**

Objectives This is a feasibility study of the coupling of a biomass gasification process, converting the energy of biomass directly to hydrogen, with fuel cells for electricity and heat generation. Phosphoric Acid Fuel Cells (PAFC) are considered, in small modular units of a few MWe capacity as they represent an industrial reality, readily available in appropriate commercial size for field operation. The proposed coupling of biomass gasification and fuel cell is characterized by high energy conversion efficiency and very low environmental impact: this provides for easy integration into small-to-medium size agricultural concerns. Electricity could be either sold or consumed internally; heat would be used for heating or other internal processes. The activities are directed towards the study of such systems, both technically and in terms of the technical and economic constraints on siting in the rural context. Technical Approach The research study will start from an exchange of information concerning the characteristics and requirements of the various sub-processes (fluidized bed and entrained bed gasification, phosphoric acid fuel cell electricity generation), through laboratory investigations in well-defined key areas (biomass pretreatment, catalytic conversion, and cleaning of the gasification product), to conceptual design of the integrated systems and estimation of system investment costs. Biotec is investigating the most important aspects related to general plant siting and to the biomass pretreatments which are needed to transform the harvested crops into suitable feedstock for gasification plant. University College London and Noell Energy are performing the process design of the fluidised bed system and the entrained flow gasification process respectively. The Univ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'SPOOLABLE COMPOSITE FLOW LINE FOR OFFSHORE USE, C-FLOW' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

The aim of the project is to run a full qualification of a composite flow line pipe to demonstrate that these small diameter pipe lines are suitable for :1. Transportation of hydrocarbons, and2. Transportation of sea water for water injection;The composite flow lines will be within the dimensions 100-250 mm, with a pressure rating in the 100 to 350 bar range. In order for the oil industry to commercially exploit Spoolable composite flow lines, there is a need to qualify and demonstrate the product, the end connectors, the installation, and the operation. Also, the writing of engineering specifications and design manuals are important elements in demonstrating the technology.The design phase is almost completed. Loads for a composite flow line has been identified and defined. Rules and regulations have also been identified. A number of designs has been analyzed both with simple methods and with Finite Element Method. An end connection has been designed and analysed and is under manufacturing. Also, in the Manufacturing Phase several flow line laminates has manufactured. A total 270 m with inner diameter from 63 mm to 100 mm of different designs has been made. Characterization testing of some of the pipes is completed. Results so far are encouraging and meet both the requirement for bending and for pressure containment.The technical innovation is continuous pipe manufacturing of composite flow line pipes for offshore use as hydrocarbon flow lines or water injection lines. COMPIPE has developed the manufacturing process. Long lenghts of several km can be manufactured without joints and spolled onto a spool or reel for storage, transport and installation. Advanced fibers such as carbon fiber, glass fiber as well as epoxy resins are used. Composite material flow lines has no
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The european virtual institute for plastic processing' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

Plastic processing industry composed mainly by SMEs need the support of a pan-European organization as the proposed EuroVIPP, linking geographically scattered competences (highly specialized know-how, experience on infrastructures) to adapt their activities to the new globalize marked; contributing to the improvement of the competitiveness. EuroVIPP partners submitted the Eol approved by the EC for the European Virtual Institute of Plastic Processing in the belief that plastic processing sector was demanding structure (like the proposed) to support their technology needs. More and more plastic components are part of hi-tech products, with extreme requirements (medicine devices, transport information technologies (IT...). EuroVIPP aims to help SMEs to face this challenge creating a technological frame, looking at industry needs both on actual and long time horizons, to forge the sustainable growth of the plastic processing sector. For the first time, a powerful combination of some of the largest and most effective plastic specialist RTOs in Europe together with Academic leaders will provide direct access to more than 5,000 technicians, engineers and scientists. EuroVIPP's activities will contribute to the fulfillment of EU Policies relating to Research and Technology, Industry Enterprise, Environment, the internal Market and Health & Safety.