RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Seamless Human Robot Interaction in Dynamic Environments'.

assistant: **Objectives**

A major barrier exists preventing today's and future interactive robots from smoothly acting in joint workspaces in real-world and in an efficient and socially compatible manner on human terms. Robots lack the ability to plan actions in a timely manner in order to match dynamics of environment and humans. Environment and human motion dynamics have to be known and represented in a way that sufficient prediction and planning quality is provided even in complex dynamic scenarios with many interaction partners accounting for social aspects. Robots need to be aware of human communication principles in order to estimate intentions and to predict future behavior.SHRINE aims at breaking this barrier in order to provide future robots with interactive capabilities similar to those of humans and to facilitate joint action of humans and robots sharing one world. SHRINE targets an integrated approach towards interaction in complex dynamically changing human-centered environments in terms of a hierarchical framework. SHRINE will investigate dynamic systems approaches to haptic and affective communication in human-robot interaction to consider intention and affect within an integrated robotic control and action planning framework. SHRINE seeks to extend the conventional, purely physics-driven motion prediction approach by estimating intentions of humans and merging these estimates with the dynamic physical environment model. SHRINE will integrate findings from psychology and sociology into the latest path planning and navigation methods.The approach of SHRINE is highly innovative with pioneering character in the integrated approach as well as in the various sub-fields, strongly interdisciplinary bridging engineering approaches and human sciences, and constitutes visionary high-risk re
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Further training courses for Rodos operators' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

The performance of training courses for RODOS operators is one important step forward in the ongoing process of introducing the RODOS system within Europe, in particular the EU and the accession countries, and in ensuring its operation by qualified personnel. Only with a detailed knowledge of the system' s functions, its capabilities and the results achievable, the RODOS system will become a valuable support tool within the national emergency arrangements. The complete set of the training material together with the RODOS documentation will be made available t o the countries operating RODOS now or in future. Guidelines for customising the training course and material will help perform national training courses for the continuing education of RODOS operators. The proposed two further training courses are a supplement to the four training courses held in the years 2000 to 2002.A number of countries, both in East and West Europe, have taken the decision to install the RODOS system in future as decision support tool and for managing the off-site emergency response after nuclear accidents. Precondition for its successful implementation and application in emergency centres is the intensive training of people responsible for its operation. Only with a detailed knowledge of its functions, capabilities and the results achievable the RODOS system will become a valuable support tool within the national emergency arrangements. The overall objective of this proposal is to repeat in spring 2003 and 2004 the already existing and four times successfully held training course for operators of the RODOS system in emergency centres. In that way, those countries, where the system will be installed in the next years, will have the possibility to train their staff members for obtaining the ne
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'CATALYTIC ENANTIOSELECTIVE DESYMMETRIZATION OF PHOSPHORUS (V) CENTERS' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Compounds containing one or more phosphorous atoms in the P(V) oxidation state are important to chemistry, biology and medicine. These include marketed antiviral drugs such as Remdesivir, and Sofosbuvir; the former garnering interest as a potential treatment for COVID-19, and the latter being on the WHO list of essential medicines for the treatment of Hepatitis C. Accordingly, new and improved methods for the efficient synthesis of P(V) containing compounds, especially in an enantioselective fashion are essential. Although promising protocols are beginning to arise for the synthesis of racemic P(V) compounds, new strategic approaches for the stereoselective synthesis of P-stereogenic centres are limited and catalytic enantioselective approaches remain unknown. Herein we propose to exploit our modular and tunable superbase catalyst platform, to design, discover and develop new iminophosphorane catalyst systems that will allow the direct and enantioselective synthesis of chiral phosphates, phosphonates and their analogues, in a single enantioselective step. We wish to capitalise on the abundance of commercial phosphorous (V) starting materials to allow the ready and scalable preparation of suitable symmetric prochiral precursors and through a suitable catalyst-enabled desymmetrization generate, in high enantiomeric excess, synthetically relevant chiral phosphorous intermediates. The fellow has already acquired a notable, high-level skill set and has demonstrated his excellence throughout his career, however this challenging project will extend his capabilities and improve his skill base and further enhance his scientific potential. DESYPHOR will therefore bring vital new knowledge to the field of catalytic enantioselective desymmetrization, deliver important methodologica
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Hercules' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

More than fifteen Large Installations (L.I.) of neutrons (N.) and Synchrotron Radation (S.R.) are operating in the European Union, providing in the field of biology, chemistry, physics, geosciences and industrial applications, sophisticated instrumentation for the study of various materials. An important need for a basic training has been clearly expressed by the community of European users of these L.I. The HERCULES Courses are designed to train young European researchers either PhD students or post-doctoral scientists to optimise the present and future use of these L.I., that is to take advantage of the state-of-the-art instruments for their research work. One of the aims is also to help build a European network of young researchers using n. and S.R. for condensed matter studies.The specificity of the programme is to offer a basic theoretical and experimental training to a multidisciplinary audience composed of young biologists, chemists, physicists, geoscientists and industrial scientists in a unique scientific site in Europe where two European L.I., ESRF and ILL are located with their exceptional instrumental and technical infrastructure, as well as their associated high level human potential. The high level programme proposed here is given by the best European specialists to selected European young researchers in a privileged scientific environment on basic n. and S.R. methods and instruments and their applications to physics, chemistry, biology, industry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Star formation in the central regions of active galaxies and data mining in radioastronomy at sub-millimetre wavelengths' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

The objectives of this proposal can be summarised as follows:Scientific aim:The proposed project is focused on the onset of nuclear activity in the absence of interactions. The dense and warm molecular gas plays a key role in this process, and its morphology, kinematics and physical properties will be traced by means of (sub)millimeter data using the first interferometer working at submillimeter wavelengths, the Submillimeter Array (SMA).This study will allow selecting the best candidates to be followed up with the high angular resolution provided by ALMA. This research will be performed in the framework of the AMIGA international collaboration (http://www.iaa.es/AMIGA.html) whose aim is to study the interplay between interstellar medium, star formation and nuclear activity in a well-defined sample of the most isolated galaxies.Technical aim:- Participation in the development of a submillimeter calibration scheme for SMA. This is especially relevant and directly applicable to the development an d commissioning of the Atacama Large Millimeter Array (ALMA), instrument that is being built by an international consortium -Europe, USA and Japan- and is one of the most important investments of the European ground-based astronomy.- Development of data mining tools for (sub)millimeter interferometry, focusing in a pre-reduction pipeline. These tools are particularly necessary in view of the large amount of data that SMA and ALMA will generate. The scientific and technical progress in submillimeter astronomy will culminate with ALMA due to its unprecedent resolution and sensitivity.The commisioning phase will begin soon (2007) and is expected to be completely finished by 2012. With the here proposed project the applicant intends to be prepared before the ALMA commissioning phase
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'METAMORPHOSIS' under Horizon Europe.

assistant: **Concept**

The Researchers´ Night is one of the favorite science popularization events in the Czech Republic. Since its introduction in 2005, it has steadily grown in terms of scope, geographical coverage, professionalization, and attendance by the public. The consortium of 18 participating universities, research institutes, and other non-academic organizations will prepare two editions of nation-wide ERN in collaboration with numerous stakeholders spread across the country.As in previous years the program is built around a shared topic: „Franz Kafka“ in 2024 and „Golden Coins” in 2025. For maximum reach to the relevant target groups, a coordinated awareness campaign including a common website, emblem, and graphic design will be carried out as well as impact evaluation.The key novelty will be introduced via the Researchers at Schools Activity (RaSA), reaching out to schools in remote areas. In 2024, researchers will visit schools with interactive sessions and school groups will be brought to experience ERN at one of the METAMORPHOSIS partners, while in 2025 the schools will be supported in organizing their own “mini Researchers´ Nights”. Based on the long-term experience of some of the project partners with bringing researchers to primary and secondary schools, an open-source handbook will be created.The conference for science popularizers will provide enthusiastic researchers with the necessary skills and a platform for sharing ideas. Researchers involved in EU-funded projects, including MSCA fellows and ERC grantees, and Erasmus students will help present the benefits of the EU support to science and innovation. Outreach activities will be also focused on raising awareness about EU missions. In addition, two gender-imbalanced STEM fields will be flagged, promoting “Girls in IT”
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Structure and function of intrinsically disordered proteins (IDPs) in cell cycle regulation' (IDPs) under Seventh Framework.

assistant: **Objectives**

In the classical structure-function paradigm the function of a protein is associated with its three-dimensional structure. However, recent studies using single-molecule FRET, NMR and other techniques have questioned the idea that proteins are static molecules. This phenomenon is exacerbated especially in the proteins that are fully or partially unstructured, termed intrinsically disordered proteins (IDPs). 30-40% of eukaryotic protein sequences have been found to contain long disordered regions under physiological conditions, based on their amino acid composition. The intrinsic flexibility of IDPs affords functional advantages in molecular recognition. One of the most prominent examples is the disordered polypeptide p27: Through its dynamic intrinsic properties it is able to regulate eukaryotic cell division by interacting with a number of cyclin-dependent kinase (Cdk)/cyclin complexes, as well as with other nuclear and cytoplasmic targets. The inherent flexibility of p27 is essential for the high affinity interaction with the kinase complex, but also for post-translational modifications, including phosphorylation and ubiquitination followed by proteosomal degradation. Importantly, phosphorylation of p27 by oncogenic kinases contributes to tumorigenesis in several human cancers. The crystal structure of p27 bound to Cdk/Cyclin complex and ensemble measurements provide molecular details of the specificity and the sequential induced-folding mechanism of this interaction. However, the mechanistic details of this phenomenon are largely understudied in contrast to the conventional protein-folding problem. By applying single-molecule spectroscopy in combination with kinetics, thermodynamics and site-directed mutagenesis (Phi-value analysis), we will provide a basis for unders
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Hypothalamic Lipotoxicity and Endoplasmic Reticulum Stress: a New Pathophysiological Mechanism of Obesity' (OBERSTRESS).

assistant: **Concept**

It is well established that metabolically relevant organs such as adipose tissue, pancreatic beta cells, liver and skeletal muscle develop endoplasmic reticulum (ER) stress under conditions of obesity induced lipotoxicity. Here, the applicant will investigate if/how the hypothalamus is affected by lipotoxicity and ER stress in the context of obesity* Scientific Hypotheses:1. Obesity is associated with lipotoxicity and ER stress in the hypothalamus.2. Hypothalamic ER stress may contribute to the development of obesity through dysregulation of the mechanisms controlling energy balance.3. Based on our preliminary data, we hypothesize that CHOP, a mediator of ER stress, could be a key modulator of the association between obesity and ER dysfunction in the hypothalamus.* General Objective: to determine the relevance of hypothalamic lipotoxicity and ER stress for the development of obesity and whether targeting ER stress mechanisms is a successful therapeutic strategy to prevent or revert obesity and its metabolic complications.* Specific Objectives:1. To determine whether obesity and the metabolic syndrome are associated with hypothalamic lipotoxicity, ER stress and whether these effects are hypothalamic nuclei specific2. To determine whether primary hypothalamic ER stress is a cause of altered energy balance leading to obesity and metabolic complications3. To determine whether in the context of obesity inhibition of ER stress in hypothalamus affects energy balance and obesity associated metabolic complications4. To determine the role of CHOP on energy balance and obesity in specific hypothalamic neuronal populationsThis project is central to the applicant’s goal of understanding how the hypothalamus regulates energy balance under physiological and pathophysiological conditio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Coordination Action to maintain and further develop a Sustainable MAritime Research in Europe' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Under CA ACMARE, the ETP WATERBORNE (WB) has completed its initial phase and has established itself as a key adviser to and a strategic partner of the Commission for the generation of consensus views relating to maritime research policy. After three years, the CA ACMARE has developed and published the WB Research Strategy in three key documents: the Vision 2020, the WB Strategic Research Agenda and the WB Implementation Route Map. The Coordination Action CASMARE aims to provide support to the maritime community so that the ETP WB can move forward to its next objective which is the implementation and delivery of the WB Research Strategy. By using the successful consultation processes established within the ETP, CASMARE will continue to raise awareness of the WB Research Strategy and to broaden the consensus among the stakeholders, with a special emphasis on engagement with national programmes and industry activities. CASMARE will inform stakeholders to stimulate and mobilise the maritime research resources so that the WB Research Strategy will find wide acceptance and the outcomes will be realised. CASMARE will assess RDI results from EU and national programmes and monitor the progress against the WIRM. CASMARE will expand the platform’s horizons within and beyond maritime transport by linking with other transport ETPs, ERANets, and with any other relevant research grouping or initiative outside transport such as MANUFUTURE and the Marine Science World. WB’s critical enablers include the development of human capital, education and the protection of IPR, The advancement of education and training presents significant opportunities to improve the situation of the WB community. WB related lead markets will be analysed and recommendations will be made to the relevant deciders
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Longitudinal welding by the laser and/or the plasma laser process of high grade pipelines up to 16 mm thick for energy transport' to be submitted under Fifth Framework.

assistant: **Abstract**

The overall objective of this project is to produce a high-grade steel pipe with high toughness properties and resisting to hydrogen cracking, both in the base metal as well as in the welded zone. This product with a very high added value will be used on a promising market, that of high volume energy transport (gas) and complies with improved environmental respect. This product is produced using the laser welding technique. The main deliverables suitable for exploitation at the end of the project are the following: Development of a new technology based on plasma/ laser welding for large pipe with thick section, a development of base metal and filler wires, the introduction of functional and integration specifications regarding the welding machine for line pipe production lines, drafting of guideline based on all the results obtained in this project.