RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Portable electrochemical assay system for on-chip quantitative estimation of bladder cancer biomarkers in real samples' (2014-2020) under Horizon 2020.

assistant: **Objectives**

Cancer is a leading cause of death worldwide and the best approaches to improve cancer survival rate is to diagnose it at an early stage. In spite of the rapid explosion of new technology platforms, traditional optical ELISA is used in clinical practice, which is laborious, time-consuming, require large sample volume and suffer from low sensitivity. On the other hand, recently proposed electrochemical sensors which promise easy operation, accuracy, high sensitivity, low cost and compact size mainly suffer from background signals, non-specificity and selectivity in clinical samples. Therefore, there is an urgent need to solve the key issues in the development of clinically relevant and commercially viable technologies that enable screening of high-risk individuals for cancer at an early stage. The proposed program is to develop a reliable point-of-care (POC) diagnostic system based on a multidisciplinary approach of integrated microfluidic and electrochemistry for multiple biomarker detection in clinical samples. The proposal aims at finding solutions for key issues of non-specificity, sensitivity and selectivity in clinical samples for sensitive and multiplexed detection. The proposal will address the above mentioned challenges, via separation of assay chamber and detection chamber with innovative surface chemistry and microfluidic design with electrochemical detection techniques. Work will be focused on bladder cancer as a test model to solve the above mentioned issues. The proposed device will be of bench top size and have capabilities to detect a panel of 3 or more biomarkers simultaneously. The successful outcome of the project will result in high impact publications, technology know-how and IP, which will be used to design and develop a prototype device. A secondme
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Tencompetence: Building the European network for lifelong competence development'.

assistant: **Objectives**

TENCompetence will support individuals, groups and organisations in Europe in lifelong competence development by establishing the most appropriate technical and organizational infrastructure, using open-source, standards-based, sustainable and innovative technology.To this end TENCompetence will conduct RTD activities to further develop and integrate models and tools in four specific areas: the creation, storage and exchange of:- knowledge resources,- learning activities and units of learning,- competence development programmes and- network data for lifelong competence development.This will result in:- New innovative pedagogical approaches, assessment models and organisational models for lifelong competence development, supported by the TENCompetence technical and organizational infrastructure.- Software for the effective support of users who create, store, use and exchange knowledge resources, learning activities, units of learning, competence development programmes and networks for lifelong competence development.- Integration of the isolated models and tools for competence development into a common framework.The consortium will conduct pilots in digital cinema, for health workers, competence development in water management and city-wide contexts. It will disseminate its products widely and for free, using open source and creative commons licences; develop new business models for companies active in publishing, training provision, education, HRM and technology support; train associated partners, and especially SMEs, to deliver these services; and develop at least three new specifications for standardisation.The TENCompetence infrastructure can provide a tremendous push towards further integration and collaboration in support of the European knowledge society. It can b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Community-Based Smart City Digital Twin Platform for Optimised DRM operations and Enhanced Community Disaster Resilience' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

PANTHEON will design and develop a Community based Digital Ecosystem for Disaster Resilience utilising Smart City Digital Twin (SCDT) technology and leveraging new and emerging technologies and innovations to improve risk assessment, reduce vulnerability, and building community disaster resilience. The aim is to enhance the operational capabilities of CBDRM (community based DRM) teams, by: a community based smart city digital twin environment with components used for simulations, training and evaluation of the behaviour of sub-systems, threats and human factor; an early Detection and Situational awareness environment enabling authorities and FR and SR (first and second) even in complex, remote and demanding locations; an integrated intelligent subsystem, by the utilization collaborative sensing from earth observations and swarms of UAVs optimized to autonomously perform UAV-assisted operations throughout all disaster phases. PANTHEON platform and technologies will be combined with IoT infrastructure, multi-source data (satellite and in situ data, social networks, historical data)  to create a tool for assessment of risks, vulnerability and capacity assessment; disseminate and inform decision makers and the public for risks during disasters; engage citizens and stakeholders in the disaster resilience building and share knowledge and best practices; identify vulnerabilities and implement policies, strategies and plans to eliminate future disaster costs; enhance collaboration among people at the local level; promote the conduct of comprehensive surveys on multi-hazard disaster risks and the development of regional disaster risk assessments and maps, including climate change scenarios; promote and enhance, through international cooperation, including technology transfer, ac
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Next Generation Energy Efficient, Inexpensive Hydropneumatic Hybrid Actuation System' (HYPAS).

assistant: **Concept**

The importance of automation in the process industry has increased dramatically in recent years: the global industrial actuators market generated 3,023 million € revenue in 2013, and is expected to grow at a compound annual growth rate of 5.9% between 2013 and 2018, with Europe being the leading target market. Within this particular market, the demand for inexpensive hydraulic/ pneumatic actuators integrated with electronics to adopt new end-user applications will increase, and it is expected to have crucial impact on the market.HYPAS brings together the advantages of both a hydraulic and a pneumatic operated system while eliminating disadvantages of both systems: allows high energy savings (up to 50%), high precision (up to ±0,1 mm), has a very compact design due to the small number of components from which it can be constructed and is inexpensive compared with actual conventional products: target retail price is €700, which is estimated to be approx. 30% cheaper than comparable products offering similar features.The overall system advantages and the actual growing demand by those industries where accurate control of motion and position is contradicted by a low cost requirement, presents a great business opportunity to introduce our novel actuator in the market.HYPAS is the direct response to customer needs and a key vehicle for Air Bonaita SRL to leverage our 34 years of commercial experience and develop a competitive product to differentiate ourselves from competitors to enable, firstly, further consolidation in the Italian market and, more importantly, our growth outside Italy. Projected turnover for Year 2016 to Year 2020 is 140K€, 1190K€, 2086K€, 2590K€, and 3532K€, respectively. To continue in a steady pattern of growth, we plan to attract a larger customer base
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Characterization of a novel population of olfactory sensory neurons in the main olfactory epithelium' (Mouseolf).

assistant: **Concept**

Sensory organs allow animals to extract information from their surroundings, and to build a representation of the outside world. A good representation of the environment is a prerequisite for an organism to respond to its peers, predators or prey, for example. To do this, various organisms rely heavily on their sense of smell. Indeed, olfaction is the most important sense for many animals, including mice.The mouse olfactory organ is composed of neurons, which each express a single type of chemosensory receptor. These receptors are involved in detecting odorants or pheromones and are the foundation block of olfaction. Until now, five major families of olfactory chemoreceptors have been identified, all of which are G-protein coupled receptors. Recently, the Rodriguez lab has identified a novel population of neurons in the main olfactory epithelium (MOE) defined by their expression of TrpC2, a protein usually absent in this area. Preliminary evidence suggests that these few thousand neurons do not express any of the five types of known olfactory chemoreceptors and are thus likely to contain an undefined receptor family. Here, we plan to use a novel approach to identify these receptors. We will use fluorescence-activated cell sorting to specifically isolate the population of interest from transgenic mice engineered so that the TrpC2-expressing neurons are fluorescently labeled. We will then perform deep-sequencing of these neurons’ transcriptome to identify candidate chemoreceptors, and will further characterize these candidates using RT-PCR and in situ hybridization.In addition, in a separate approach we will generate a knock-in line allowing us to conditionally silence the TrpC2 neurons in the MOE. Using various standard assays, we will test the behavioral role of this ne
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Connecting Energy National Contact Points in a pro-active network under Societal Challenge 3 'Secure, clean and efficient energy' in Horizon 2020'.

assistant: **Innovation**

C-ENERGY 2020 is a 48 months Coordination and Support Action having the specific objectives to Ensuring high quality Energy NCP services for Horizon 2020 and related programmes applicants; Lowering entry barriers for Energy NCPs approaching EU Framework Programmes for R&I for the first time; Consolidating the network of Energy NCPs. C-ENERGY 2020 project will take into consideration the significant changes that Horizon 2020 has brought about the Energy NCP mandate. With its brand new approach to R&I Horizon 2020 demands Energy NCPs: a) to address their services to a wider target, b) to have specific multidisciplinary competences. C-ENERGY 2020, whose consortium is composed by experienced and less experienced Energy NCPs from 18 countries, will tackle these challenges building up the NCP capacity by organising benchmarking activities, at least 8 training sessions and 12 twinning schemes. The dialogue with energy participants will benefit of at least 2 enhanced cross-border brokerage events and 9 training sessions for stakeholders. The project will also take special care of outreaching activities by extending the collaboration with other NCP thematic networks, cooperating with EEN, working on partner search and cooperating on international relevant activities. Finally, communication within and outside the Energy NCP network and the dissemination of results will be ensured through the website, the development of promotion/information materials, the participation at major events and PR activities and an e-mail alert service/newsletter. Throughout the project special attention will be paid to the diversity of stakeholders in the energy sector, the gender dimension, as well as to establish links with other EU relevant initiatives, programmes and policies.


**Keywords:** trai
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'GMES for Regions: Awareness and Access Link' (GRAAL) under Seventh Framework.

assistant: **Objectives**

The overall objective of GRAAL is to foster the development of GMES Downstream Services and develop the link of GMES with Regions (and other local authorities of comparable importance).The essence of GRAAL lies in the balance between these two sub-objectives. The members of the GRAAL consortium believe that there is as much a need to develop the awareness of GMES in LRAs as it is necessary to ensure that there are Service Providers in a position to serve this market and to accomplish the Lisbon strategy-related objectives of GMES.It is proposed to achieve this overall ambition through the following objectives:• To characterise the offer in terms of GMES services for LRAs;• To establish an observatory of the GMES Downstream Service sector;• To develop a user oriented tool implemented on a Website where demand and offer will meet and where exchanges can take place by using the most advanced web-based technologies;• To increase awareness of GMES among LRAs and potential Service Providers;All the activities shall be conducted in coordination with the DORIS_Net project. To maximise the overall efficiency of the work performed by the two projects, this coordination will be based on a clear distribution of tasks and targets.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Relative roles of cell surface IP versus intracellular nuclear receptor PPARbeta in the sensing and signalling of prostacyclin' (IPVSPPARB).

assistant: **Innovation**

Prostacyclin is a powerful endogenous mediator involved in the regulation of a number of essential biological processes.Key functions of prostacyclin include:(1) inhibition of platelet aggregation,(2) vasodilatation,(3) inhibition of vascular cell proliferation and inflammation and(4) reduction of cholesterol accumulation.Prostacyclin and its metabolites are clinically used to inhibit platelet aggregation (if heparin is contraindicated) and to treat pulmonary hypertension. Indeed, it is the only medication for PAH that has shown a survival benefit in a randomised clinical trial. Prostacyclin is produced by endothelial cells following the consecutive actions of cyclo-oxygenase and prostacyclin synthase. The actions of prostacyclin are mediated by two receptor classes: cell surface IP receptors, linked to adenylate cyclase, and nuclear receptor PPARbeta which regulates the transcription of several target genes to mediate cellular responses. Most recently we have shown that PPARbeta is active in platelets, which have no nucleus, suggesting that it may also have non- genomic effects.The relative roles of IP versus PPARbeta in the sensing and signalling of prostacyclin by tissues of the cardiovascular system is not known. In the current application we seek to use selective pharmacological tools and cells from genetically modified mice (where IP or PPARbeta have been knocked-out) to firmly identify how IP and PPARbeta receptor systems act and interact when cells or platelets are treated with prostacyclin and related compounds.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Secretariat of the Technology Platform for the Electricity Networks of the future.' under Sixth Framework.

assistant: **Concept**

The objective of this project is to establish a secretariat to support the Technology Platform for the Electricity Networks of the Future (SMARTGRIDS) in efficient and transparent management of platform activities, projects, results and communication strategy and so contribute to achieving the statutory platform objectives and ensure their highest quality. Main activities: -Support to the platform groups in organisation and management of periodic meetings -Generation of high-quality results - implementing monitoring activities and quality control reviews of deliverables -Internal IT support service for communication, document and knowledge management. -Implantation of communication strategy (information centre (public internet site), project info-tool, periodic newsletter and 2 international conferences. The consortium comprises two complementary partners uniting all necessary skills for successful completion of the objectives. AIZABALA - independent international consultancy of 50 professionals with: offices in Pamplona, Brussels and Madrid; 20 years experience in RTDI project management, own Studio Knowledge Management tool" for internal knowledge management and managing innovation activities of 200 clients, profound knowledge of the Electricity Network sector through management and participation in over 20 European energy projects from FP4 to FP6 and in the preparation of Studies for the EC. OTTI e.V. has a 30-person strong team to coordinate and promote seminars, specialist forums and conferences, and a specifically dedicated Renewable Energies Department. This department has been responsible for a great number of national and international conferences for the energy community and most importantly, OTTI was responsible for the conference on the "Integration of Renew
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Tribological behaviour under loss of LUBrication of new optimized GEARs for friction reduction in power gearboxes' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

LUBGEAR aims at demonstrating gear design solutions which can withstand off-design conditions in geared turbofans without additional means (secondary/auxiliary lubrication). Those solutions combine 1) optimized gear geometry providing low power loss conditions; and 2) Surface and material combinations providing low friction. The solutions aim at reducing friction losses and frictional heat, leading to reduced temperatures and risk of scoring. This will allow producing gears which do not face catastrophic damage even under loss of lubrication in off-design conditions.An investigation of new enabling technologies regarding off-design conditions will be carried out in simulation and experiment at contact level (TRL2). The combination of material systems (roughness, coating and hardening), contact load, sliding speed, rolling speed, lubricant type and lubricant supply will be considered through a Design of Experiments, allowing LUBGEAR to create a unique database and extend contact modelling tools.Gear Design Optimisation takes into account the results from contact level and derives solutions coming from geometry, material systems, operating conditions and passive lubrication. A demonstration of the most promising design and technology solutions for gears will be validated in an experimental component test rig at TRL3 level. Gear modelling addresses the predictive design of off-design conditions.LUBGEAR project gathers 4 strategic partners based on a multidisciplinary approach combining uniquely engineering, tribology, mechanics and advanced chemistry. This will allow developing a gear design with an increase of over 100 % in scoring load and a reduction of over 50 % of frictional losses resulting in remarkable improvements in loss of lubrication conditions. LUBGEAR will as
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The interactive european network for industrial crops for industrial crops and their applications in the changing millenium' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Markets for non-food crop products are emerging, but development is hampered by uncoordinated efforts, lack of sector structure & produce specifications. End users are often unaware of benefits of & opportunities for non-food products. There has been much 'science push' but market orientation is now the key to success in this sector. This project will characterise markets & specifications for primary produce as major targets, & ensure focused networking & information transfer to the whole industry. The project will disseminate information at meetings; assess potential for non-food crops in EU accessing/associated states extend a database of products from plants; verify market size/specification for non-food crop products & disserninate on website & data sheets; extend existing non-food contacts; measure uptake of non-food crops.