RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Optimal Cellular Prediction'.

assistant: **Objectives**

The ability to respond to changes in the environment is a defining property of life. Strikingly, experiments have vividly demonstrated that even single-celled organisms can leverage correlations in the environmental fluctuations to predict the future environment and mount a response ahead of time. Yet, how reliably single cells can do so and what the fitness benefit of prediction is, are wide-open questions.To predict the future environment, cells need to compress the past signal into the dynamics of the intracellular biochemical network from which the future input is inferred. Yet, storing information is costly while not all features of the past signal are equally informative on the future input signal. Using measures from information theory and ideas from statistical physics, we will study network motifs and environmental stimuli of increasing complexity to derive the fundamental limit to the prediction accuracy as set by the information on the past. We will determine how close biochemical networks can come to this bound, and how this depends on the topology of the network and the resources to build and operate it  protein copies, time, and energy. We will elucidate how the features of the past signal that are most informative about the future signal are encoded in these optimal networks, and how the cell decodes these. The studies on these minimal model systems will uncover general principles of cellular prediction.We will use our theoretical framework to set up experiments that allow us to test whether two specific biological systems  the E. coli chemotaxis system and the glucose sensing system of yeast  have implemented the uncovered design principles for optimal cellular prediction. We will measure how close these systems come to the fundamental bound on the predi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Certification of Reference Materials for the Analysis of Asbestos Fibres in Lung Tissue'.

assistant: **Concept**

International trials have revealed serious discrepancies in electron microscopic methods used for the determination of asbestos fibres in lung tissue. Reliable results are of crucial importance for the diagnosis and compensation of asbestos-related diseases such as mesothelioma and lung cancer.This project will produce two batches of dry, homogenized lung tissue with a certified content of asbestos fibres. The objective is to reduce the current interlaboratory inaccuracy of several-fold differences to the same level as the inevitable variation (less than 50 %) caused by different sampling sites when tissue samples are taken during autopsy or surgery from various parts of the lungs.A feasibility study including preparation, homogeneity and stability tests has been completed in 1996. Scanning electron microscopic counting showed no inhomogeneity of the asbestos concentration and the matrix composition was homogenous as verified by iron and zinc analyses. The storage stability was good for samples stored at -20(C, +20(C and +40(C. In a preliminary comparison, the interlaboratory variation was less than 35 % for anthophyllite, amosite and crocidolite fibres longer than 1 micrometer. The certification measurements are in progress.After the homogeneity and stability of dry tissue powder have been tested, the materials will be packed into glass vials as 100 mg units. The content of asbestos fibres will be determined by transmission electron microscopy in the eight participating laboratories.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Autoforestation Mode: ON' (2021-2027), addressing dissemination and exploitation.

assistant: **Impact**

At the current deforestation rate, it is estimated that there will be no forests left in between 100 to 200 years. As such, restoring woodlands has become a priority for nations but remains a massive challenge worldwide. Destruction is easy but forest restoration has inherent problems of scale, speed, efficiency, and cost. The modest results of massive reforestation projects show that the current state-of-the-art solutions cannot get the job done fast enough. Forestry is significantly behind, compared to other sectors, in digitalization, precision and efficiency.Forest Maker is a new-generation integrated automated planter platform - an all-in-one solution that performs the entire planting and data collection process without stopping, guided by software for the creation of a digital twin of forest for precise and easy management.


**Keywords:** Precision forestry,Survival rate,Carbon dioxide absorption,Silviculture,Reforestation,Forestation,Service innovation,Environmental and Green Technologies,Automation and control systems,Automation,Engineering and technology
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Novel precious metal-based bionanocatalysts from scrap' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

Strategic precious metals, SPMs are important catalysts for chemical & pharmaceuticals, in addition to fuel cells and auto exhausts. As demand increases the price of SPMs is accelerating and the commercial and technical need for cost effective recycling becomes more pressing. Current recycling techniques use strong chemicals, are energy intensive and rather inefficient, for example only of the order of 6% of the SPMs in car catalysts are recovered. This proposal seeks to synthesize novel and superior catalysts from recovered SPMs. The proposed route will combine two biotechnologies for clean SPM recovery with concomitant bulk biosynthesis of novel bionanocrystal catalytic materials. It will build on the results of an ongoing EU project to steer the structure of the harvested SPMs for simultaneous fine catalyst manufacture.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Stable equivalences of Morita type'.

assistant: **Objectives**

Representation theory of groups, rings and algebras describes and compares categories of modules or representations, or related categories such as derived or stable categories. Equivalences between such categories need to be studied in order to reduce new examples to known ones and to exhibit new connections between seemingly different situations. While the classical notion of Morita equivalence is well known, much less is known about equivalences of derived or stable categories, which are the source of major current problems and conjectures. This project will study stable equivalences of Morita type, which form the class of stable equivalences needed in most applications and which are closest to derived equivalences. A general theory needs to be built, connections and comparisons with derived equivalences have to be clarified or established, and applications, e.g. in representation theory of finite groups and in algebraic Lie theory, are envisaged. The project will support an outstanding young Chinese researcher in becoming a research leader in his home country.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'An EXTRAordinary DAY with Very Normal People' (EXTRADAY) under Seventh Framework.

assistant: **Objectives**

Research as “a profession like any other”: this is the concept at the centre of the entire project. The aim consists of demonstrating that in their ordinary activities and day-to-day work, researchers, such as other professionals, participate in general social and economic development. This will allow researchers to be shown in a more “ordinary” light, free of the mysterious aura that casts the profession as one that is complicated and inaccessible.To achieve this objective, the research centres involved will be transformed into a kind of virtual workshop in which the general public, particularly young people, as well as the friends and family of the researchers themselves, will be involved in the typical situations of the profession “researcher”.Children and adults will have the opportunity to understand science by experiencing its day-to-day practices, by frequenting the spaces and places where research is carried out and by coming into contact with its machinery and equipment, but above all by talking to those directly involved.The public participating will be actively involved in hands-on experiments, in a relaxed and friendly atmosphere, using also an accessible wording also for non scientists . Each of the venues for the day’s events will plan a “European corner”, providing information on Europe and European interventions in favour of researchers and research.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Supporting the research potential on emerging infectious diseases in La Réunion Island, an EU outermost region in the South-Western Indian Ocean', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

La Réunion Island is an outermost European region located in the South Western Indian Ocean. It was severely hit in 2005 and 2006 by a Chikungunya epidemic that affected a third of the population and led to dramatic socio-economical consequences. As a result, the CRVOI (Centre de Recherche et de Veille sur les maladies émergentes dans l’Ocean Indien), was launched in 2007 to be dedicated to the investigation of human and animal infectious diseases emerging in tropical regions. This Center complements, in a holistic approach of EIDs research, the existing laboratories of the Université de La Réunion working on plant emerging pathogens, phytochemistry, ecology, immunology and social sciences.RUN-Emerge aims at tackling the weaknesses resulting from the remoteness of this island, i.e. essentially scientific isolation and insufficient human resources. The main objectives are (i) to foster an inter disciplinary approach towards EIDs investigation, (ii) to tighten links of the Université de La Réunion with research partners from South Western Indian Ocean ICPCs working in this field and (iii) to open up the partnership to European leading groups, thereby extending the European Research Area and laying the ground for future participation to FP7 calls.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Stuff that Matters: Interstellar Matter in Nearby Galaxies', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

The aim of this project is to obtain the highest quality observations of the atomic interstellar medium (ISM), through observations of the 21cm line of atomic hydrogen, ever made of a substantial sample of nearby galaxies, covering a wide range of Hubble types, star formation rates, absolute luminosities, evolutionary stages, and metallicities in order to derive the detailed morphology, three-dimensional structure, and mass distribution of galaxies in the nearby Universe.Particular emphasis will be placed o n the interplay between the ISM and Star Formation, the Star Formation threshold as a function of Hubble Type and metallicity, and the physical characteristics of the cool and warm neutral ISM as traced by neutral hydrogen.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'MANAGEMENT OF INNOVATION (IN ITALIAN SMES")"'.

assistant: **Concept**

To facilitate the improvement in the competitiveness of companies through the promotion of the following tools:- Management of concurrent engineering and product life cycle- Optimisation of internal information flow- Technical project management- Technology negotiation and functional networking- Total quality management and quality assurance- value analysisTo provide SMEs (mainly in mechanical electronic, food and plastic sectors) with Innovation Consultancy Assignments which in turn will test the methodologies and provide knowledge and experience to all actors involved in the project. Some 70 SMEs will be provided with these consultancies.To start up the imitation" mechanism based on best practice and towards other SMEs, in order to multiply the effect of Community supportTo promote the creation of a "skilled environment" in the field, able to supply suitable services for each specific case.To establish an effective mechanism for skilled consultant identification and selection thus improving the quality of consultancy services in the area of Innovation Management Techniques.To disseminate the results achieved, by means of pilot-cases studies towards:SMEsconsultantsRegional Technology Advisory CentresTechnology intermediaries and Scientific ParksIMTs contractors"
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'EUropean TRanslational training for Autoimmunity & Immune manipulation Network' (EUTRAIN) under Seventh Framework.

assistant: **Objectives**

Immune-mediated inflammatory diseases (IMID) are important health challenges in Europe and beyond, afflicting an estimated 5-8% of the total population. IMID with an onset during childhood such as Juvenile Idiopathic Arthritis (JIA) cause particular concern as pediatric patients form an especially vulnerable group. Currently there is no safe and cost-effective cure for JIA and related juvenile IMID. Thus, these children face lifelong treatment with serious consequences both for the patient (high risks of long-term side effects) and for society as a whole (high costs). Translating the progress in molecular medicine into new therapies for JIA has also met with limited success. The route from idea to drug has many hurdles and is a very fragmented process.  Translational medicine encompasses the continuum of activities that extend from the conception of an idea to advanced clinical testing and, ultimately, to the development of a new medical technology or drug. This itinerary includes many components that require very different skills such as biomedical research skills, design of pre-clinical and clinical trials, regulatory issues, legal issues, intellectual property rights, communicational skills and more. Such skills are often compartmentalized within three separate domains—academia, government and industry. Each of these domains has its own set of challenges. If we are to really change the way in which we are thinking and working in the drug development process it will be essential that we start with changing the education process of our students. EUTRAIN brings together leading scientists and institutes in the field of IMID. Its goal is to provide the next generation of researchers with insights, tools and knowledge necessary to bridge the gap between bench and bedside
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Adequacy of old-age income maintenance in the EU' (AIM).

assistant: **Concept**

This proposal is presented by a group of institutes, most of which are members of the European Network of Economic Policy Research Institutes (ENEPRI) which groups leading economic and social research institutes,with wide-ranging experience in conducting policy-oriented research to high academic standards. The project proposal has two main scientific objectives:First, the work programme includes an important research component addressing the methodology of analysis of pension schemes and pension reforms. This objective is pursued in two ways: (i) by undertaking model simulations and other kinds of analysis in common and in a coordinated framework within a single workpackage and (ii) by undertaking a systematic examination of the simulation properties of simulation models including also models in application outside the Consortium.Second, the project will apply these analytical tools to examine the concept of adequacy" and undertake research on the impact on the adequacy of pensions of parametric reforms proposed in certain general plans toensure sustainability of pension systems. In general the research on adequacy assumes sustainability and analyses the consequences for the adequacy objectives.The project will shed new light on the classification of welfare state arrangements and public perceptions of pension issues. In will push outward the frontier of research on micro-simulation and semi-aggregate simulation of pension reforms and on the macroeconomic consistency of the scenarios. It will undertake systematic research on the translation parametric changes of welfare systems into incentives for early retirement and examine the effects on labour markets and actuarial fairness. Finally, but most importantly, it will provide more operational definition of adequacy of pe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Decoding the role of mitochondrial dynamics in the mesenchymal-to-amoeboid transition and melanoma metastasis' to be submitted under Horizon Europe.

assistant: **Abstract**

Tumor cell migration and invasion represent the foundation of cancer metastasis. It is therefore critical to better understand themechanisms driving a specific subset of tumor cells to invade nearby tissues. Invasive cells are known to have an undifferentiated,mesenchymal-like state. However, under specific microenvironment conditions, mesenchymal cells become amoeboid, through aprocess known as the mesenchymal-to-amoeboid transition (MAT). Paradoxically, it is not the mesenchymal cells that are moremetastatic-prone, but the amoeboid cells. What is not yet fully understood is the precise cellular mechanisms driving MAT. Emergingevidence show that mitochondria are closely linked with cellular motility, especially in cancer. Mitochondrial dynamics, consistingmainly in mitochondrial fusion, fission, intracellular trafficking and turnover, was proven to be involved in the migration ofmesenchymal-like tumor cells. However, very little is known about the characteristics of lamellipodia-localized mitochondria in thesecancer cells on one hand, and how it might influence MAT and the amoeboid phenotype on the other. Therefore, I first aim toevaluate the role of mitochondrial dynamics in tumor microenvironment-triggered MAT during the 3D invasion of melanoma cells bycombining microfluidic and optogenetic approaches. Secondly, I will characterize the lamellipodia-localized mitochondria in terms ofproteome, age, energetic and oxidative status, in mesenchymal-like melanoma cells using biochemical, microfluidic and proteomicapproaches. By the end of the project, MitoMat would significantly improve the mechanistic understanding of how mitochondria arehijacked to fuel cancer cell motility, specifically within melanoma cells with different MAT phenotypes. If mitochondrial dynamicswould p