RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'The role of depth perception during prey capture in the mouse'.

assistant: **Innovation**

The perception of depth entails the non-trivial transformation from two 2-D images captured by the retinas to a unified 3-D representation of the environment. This computation has been under scrutiny for long, but there are still many unanswered questions about how different depth cues, such as motion parallax and stereopsis, are utilized, and about the neural mechanisms underlying depth perception. In this work, I propose employing predatory behavior in the mouse, a visually guided, robust behavior, as a paradigm to answer some of these questions. For this, I will adapt existing freely behaving virtual reality technology for rendering an environment that will elicit prey capture behavior in the mouse. I will then systematically modulate the depth cues available to the animal to determine the main contributors to estimating the distance to the prey. Since the brain regions involved in depth computations are not well defined, I will subsequently use a head-fixed paradigm to perform functional, single-cell resolution calcium imaging of cortical neurons across visual areas during binocular presentation of prey-like stimuli. This will allow for identification of the neural correlates of the relevant depth cues and their location. Given that the behavior likely relies on binocular cues, imaging will target the primary visual cortex (V1) and its neighboring higher visual areas. V1 is likely the first site of meaningful integration of signals from the two eyes, and its surrounding areas also contain binocular regions. Finally, using the neural evidence acquired, I will image during freely moving behavior to identify the way depth cues are processed for successful prey capture.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Advanced Architectures Chassis/Traction concept for Future Electric vehicles' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The aim of ACHILES is to develop a more efficient E/E control system architecture optimized for the 3rd generation of EVs by integrating four new technological concepts. Firstly, a new wheel concept design will be equipped with full by-wire braking, including a new friction brake concept. Secondly, a centralized computer platform will host the e-drive functionalities and reduce the number of ECUs and networks while fulfilling safety & security requirements. It will support centralized domain controllers required to implement high automation and autonomy concepts, a key requirement for smart mobility. Thirdly, an out of phase control that will allow to intentionally operate the electric motor inefficiently to dissipate the excess of braking energy in case of fully charged batteries. As a fourth concept, a new torque vectoring algorithm will significantly improve the vehicle dynamics. The advances proposed will reduce the total cost of ownership by 10% and increase the driving range by at least 11% while increasing autonomy. ACHILES will be tested and verified in a real demo vehicle and in a brand-independent testing platform. The project consortium is another major asset. Audi, one of the technologically most advanced OEMs, will integrate these technologies to a next generation of EVs prototype. As a leading supplier, Continental will contribute by the innovative brake system. Elaphe, a leading technology company for e-motor design, will develop the suitable motor technology. TTTech, known for its future oriented network technologies for AI and autonomy-based systems, will be responsible for the networking technology. The academia team consists of the Vrije Universiteit Brussel (Coordinator), Tecnalia, Ikerlan and the Fraunhofer Gesellschaft. It will provide the technolo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'An innovative system to monitor pet’s health in veterinary clinics' in the context of a Horizon 2020 call.

assistant: **Objectives**

Dindog Tech S.L. introduces in this proposal DinbeatPRO, a wearable device to monitor pets’ health at hospital facilities to track them medically. This device will allow veterinarians to track their vital constants in real time, continuously and remotely, allowing them to grow their business. Saving money among (up to 60%) among other on consumables like electrocardiogram (ECG) patches and other medical equipment and devices, since the company has developed an innovative sensor for ECG that can pass through the fur and contact the skin, without the need to shave the pet. It also optimizes the employees’ time because they won’t need to take the pet’s vital signs manually when hospitalized. The pet market came in at a record $60.28 billion on 2016, with a growth of 4.1%. The veterinary market allows $15.92 billion of them, with a growth of 5.7% since 2015. Despite these figures, the veterinarians continue to have the same limitations since years ago when growing their business. They are not taking advantage of new technologies to help their growth and are limited through their use of traditional machines in their clinics. With DinbeatPRO they can ramp-up their business and catch up in leading technology. The wearable sends the data in real time, making available information, reports and notifications via Wi-Fi and/or Bluetooth, and saving it on the webpage and APP for further reference. With DinbeatPRO the company expects: -A potential of growth in a period of 4 years (2018-2022) of 495.85% per annum, with a turnover of 10.708.827 M€ by 2022 and a cumulative of more than 15.237.939,04 M€ in such period. - Employment increase: at least 17 staff members, starting with 8 new jobs: 3 in the Improvement phase, 2 new jobs in Launch & expansion and 3 new jobs in Technical and po
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Remote instrumentation in next-generation grids' under Sixth Framework.

assistant: **Concept**

There are numerous areas of science, industry and commerce that require broad international cooperation for their success. A number of problems may be addresses by using sophisticated equipment and a top-level expertise, which is often locally unavailable. Therefore, the development and spreading of techniques and technologies that allow virtualised, remote and shared access to industrial or scientific instruments is essential progress of the society.The possibility of using scientific or industrial equipment independent of their physical location helps in the equalization and the unification of communities and subsequently opens new opportunities for industry, science and business. Furthermore, it has a very important political and strategic impact, as we head towards a more unified Europe. The systematic identification of instruments and corresponding user communities, the definition of their requirements as well as the careful analysis of the remote instrumentation synergy with next-generation high-speed communications networks and grid infrastructure will be the base for the definition of recommendations for designing the next-generation Remote Instrumentation Services.The project results will be spread out among scientific, industrial and business groups of users to increase the awareness of benefits from using next-generation Remote Instrumentation Systems, which are essential for the equalizing access to the European e-Infrastructure opportunities. All the objectives of this project will be achieved through close collaboration of EU member states and third countries to ensure Europe's strong participation in the research initiatives conducted at the international level.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The role of stem cells in cancer development in skin and mammary gland using tissue specific expression of Gli1 protein - main effector of the hedgehog signalling pathway' (CASTEMHEDGEHOG) under Sixth Framework.

assistant: **Objectives**

Recent evidence suggests that only a subset of tumour cells is capable of giving rise to a new tumour. These tumour stem cells are functionally similar to stem cells in adult tissues and are identified in tumours of hematopoietic system, brain and mammary gland. Whether transformation of adult stem cells into tumour stem cells is the event leading to the disease is not clear. Alternatively, tumours could arise from the population of committed progenitors, which have de novo acquired self-renewal properties.The purpose of this project is to investigate the contribution of stem cell and progenitor populations into carcinogenesis in skin and mammary gland. The questions to be answered:1. Does oncogene activation alter the amount and proliferation properties of stem cells and/or progenitors?2. Are stem cells involved in carcinogenesis in skin and mammary gland?3. Are there stem cell-like cells in skin tumours?The activity of hedgehog (Hh) pathway has been shown to be required for growth of a variety of tumours including basal cell carcinoma. Here the tetracycline-controlled conditional expression of the main effector of the Hh signalling pathway - Glil in mouse skin and mammary gland is used as a model system. The dynamics of changes in the cellular composition after Gli 1 induction are monitored and the proliferative potential of different cell subpopulations is evaluated.A cross of inducible Gli1 mice and ubiquitously lacz expressing mice will be created to follow the progeny of stem cells. The potential tumourigenecity of sorted and engrafted populations of stem and progenitor cells is evaluated following Gli1 activation. Finally identification of tumour stem cells from tumours induced in Gli1 expressing mice will be attempted by cell culture methods. The outcome of this
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Modifying All Solid State Lithium Battery Interfaces' in the context of a Horizon 2020 call.

assistant: **Objectives**

The project proposal MASSIF aims at improving the fundamental understanding and control of interfaces of a battery type based on Li active materials all solid state batteries (ASSLB). The main objective is the investigation and optimization of the interfaces developing between the solid electrolyte and the electrochemically active material particles electrodes. The acquired knowledge would allow the design of optimized interfacial layers (also called artificial Solid Electrolyte Interfaces, art-SEI) capable of warrant stable interfaces. The art-SEI should allow intimate contact between the active material and the conductive particles. Our research program involves hybrid electrolytes in combination with solid state electrolytes (SSE); this approach proves to be useful to generate an art-SEI. We are going to pay attention to the positive electrode-solid electrolyte interface, which has been studied as much as the metal Li solid electrolyte interface. With this in mind, they are going to use Li2S as a positive electrode, and the last task of the project will develop a full cell using Si as a negative electrode. Si was selected as a negative electrode to avoid the problems related to Li; it is known that Li reacts with most of the SSE.The project also takes in to account the training of the researcher and the career development plan to achieve the goals and independence of the researcher. The interdisciplinary and network of the host institution will be also used to push the career of the researcher forward.


**Keywords:** Solid Electrolyte Interface, Li2S, Si, Battery
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Transcending limitations of translational research on Multiple Sclerosis and Autism Spectrum Disorder - Spectral, brain-related disorder, patient outcomes, cognition, effect, symptoms' (TRANSCEND) targeting Horizon Europe.

assistant: **Abstract**

TRANSCEND brings together expertise in biomedical, computational, behavioural, clinical, epidemiological and philosophicalresearch to advance translational research in medicine. TRANSCEND aims to add to the chronological and epistemic order of research from bench to bedside to practice with a more networked-based understanding of translation. This is particularly important in translational research on complex and chronic neurological conditions where the few low-hanging fruits of reductionist approaches seem to have been picked. TRANSCEND involves nine interlinked laboratories from clinical, biomedical, metamethodological, and philosophical sub-projects, which focus on autism spectrum disorder and multiple sclerosis. These conditions are characterised by an interconnected set of physical, cognitive and psychological symptoms, and unknown underlying disease mechanisms. While healthcare has been moving away from a purely single-cause view of medicine towards interconnected concepts of positive health, such a more complicated and nuanced notion of health and dis/ability is unintegrated within biomedical research. Most research designs are not well-suited to consider patient-relevant outcomes, the biological and social complexity of these conditions, and their implications in real-world healthcare settings, because their epistemology is oriented towards purification and reduction concerning research questions, disease models, and experiments.TRANSCEND proposes an integrative approach to translational research that embraces instead of reduces the complexity and diversity of the biological, clinical and social manifestations of the diagnoses. It will provide an innovative, interdisciplinary training along four research objectives to overcome key limitations of translational r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The biology of syncytial cells:  Dissecting the mechanisms and functions of nuclear differentiation inside skeletal muscle syncytium' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Due to their cellular anatomy, syncytial cells face many unique challenges that mono-nucleated cells do not. One of them is how syncytial cells organize gene expression among many nuclei in a shared cytoplasm. How such property is linked to their biological functions remains poorly understood. Using the skeletal muscle as a paradigm and single-nucleus transcriptomics, I recently uncovered previously unrecognized diversity and dynamics of myonuclear transcriptional programs. This conceptualized the syncytial muscle cell itself as an analog of multi-cellular tissue where individual nuclei are counterparts of differentiated cell types. My findings raise two important and unanswered questions. 1) How are the diverse nuclear identities specified and maintained? And 2) What are the functional contributions of the diverse nuclear subtypes in health and disease? I will first focus on the nuclei at the neuromuscular junction (NMJ) and myotendinous junction (MTJ), which are responsible for initiation of contraction and dissipation of contractile force, respectively. Despite their well-established functions, the mechanisms that specify or maintain them are sparsely understood. I will investigate how chromatin architecture and transcriptional regulators govern their identities. I will then characterize the upstream signalling pathways from motor neuron or tendon cells that activate the specific transcriptional programs. So far, genetic manipulation of myofibers have targeted entire muscle nuclei. To overcome this limit, I will develop tools that allow genetic manipulation in specific nuclear subtypes. Previous works had identified a new nuclear subtype associated with muscular dystrophy and a transient time window during postnatal development. I will characterize the function of th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Nanomaterial Synthesis in Highly Swollen Hexagonal Phases templates' in the context of a Sixth Framework call.

assistant: **Objectives**

The swollen liquid crystals can be used as soft templates for synthesis of nanomaterials. These swollen phases can be doped with metal ions at very high concentration without perturbing the initial structure. Our previous studies on lyotropic liquid crystalline phases (hexagonal or lamellar) with anionic surfactants have shown that it is possible to obtain nanomaterials (metals, oxides or polymers) of various morphology: fibres, nanowires, lamels... within these confined systems.   The present project is aimed at the synthesis of metallic nanostructures (using chemical and radiolytic reduction techniques), their characterisation and properties. The idea is to extend the synthesis to other liquid crystalline phases (hexagonal, cubic and sponge) obtained with cationic and nonionic surfactants and doped with various metals: Pt, Pd, Sn, Ag, Co, Ni. Small Angle X-ray Scattering experiments will allow us to analyse the structural characteristics of the doped liquid crystals.   Chemical and radiolytic (rays or electron beams) methods will be used to reduce the metal ions inside the mesophases and to obtain metallic nanomaterials of various shapes. First reduction and aggregation steps will be studied by nanosecond pulse radiolysis. Various techniques will be used to characterise these metallic nanomaterials: TEM, EELS, XPS, SAXS, AFM...We will be studying the relationship between the morphology and the catalytic activity of these nanomaterials.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Labour Policies for Inclusive Growth' to be submitted under Horizon 2020.

assistant: **Abstract**

Most advanced economies have struggled to deliver inclusive growth in recent decades. Many people are fearful about the impact on their lives of technological change, large-scale immigration, and a shifting balance of power in the labour market that seems to have benefitted employers at the expense of workers. There is a widening gap in economic fortunes between ex-industrial areas and dynamic cities with service-based economies. The stakes are high: we should not be surprised if some voters no longer support growth-enhancing policies if they do not anticipate benefitting from that growth.While it is easy to identify the problems, diagnosing the causes and finding effective solutions has been more difficult. This proposal aims to improve our analytical tools for thinking about these problems and to develop appropriate policies to respond.On the impact of technology, it will extend our understanding of the link between job polarization and inequality and analyse the appropriate skills policy. On immigration it will develop models of the impact of migration in which employers play a pro-active role as they do in many labour markets. This will be done by integrating models of migration with models of imperfectly competitive labour markets. The empirical content of these models and the implications for migration policies will be explored. On labour market competition the project will provide better estimates of how responsive recruitment is to wages offered by firms, and better measures of the gap between wages and productivity and how this varies across different types of labour markets.The intention is that the proposal will help to develop practical policies to improve people’s lives.  But it also aims to provide improved models and empirical methodologies to make a more