RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Politics of Memory and Memory Cultures of the Russian-Ottoman War 1877/1878: From Divergence to Dialogue'.

assistant: **Objectives**

“Politics of Memory and Memory Cultures of the Russian-Ottoman War 1877/1878:From Divergence to Dialogue”AbstractThe Russo-Ottoman War (ROW) of 1877-78 is part of the formation of national narratives in the Balkans, in Turkey, and in the Caucasus in the 19th and 20th centuries. The official politics of memory of these countries is based on symbols that unite, generalize and fix contradicting memories, which have been passed from one generation to the next.The ROW was a major historical event, which resulted in the establishment of a new political order in the Balkan and Caucasian regions and determined their long-term development. In the decades that followed, the peace treaties were interpreted as crucial – but in different and often opposing ways by the nations directly involved in the War (Turks, Armenians, Greeks, Georgians, Bulgarians, Macedonians and Russians). In every nation/country contradicting official cultures of memory emerged. In Bulgaria, e.g., the conclusion of the San Stefano Peace Treaty was celebrated as a national feast, but in Greece it was receipted as a tragic event because it stipulated the integration of most of Macedonia to Bulgaria. In the Ottoman Empire, the war and the following preliminary Treaty of San Stefano and the definite Treaty of Berlin have been regarded as dramatic peak of nationalist separatist movements aimed at the destruction of the Empire. Interpreted in contradicting ways, the ROW served national ideologists as basis for strengthening national identities.The overall aim of the proposed project is to prepare ground for a revision of conflicting images of the Russian-Ottoman War of 1877-78. The project considers itself positioned within the new tendencies in regional and memory studies and aims on the establishment of a networ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'In Operando Solid State Nuclear Magnetic Resonance Spectroscopy Studies of Anionic Conductors for Solid Oxide Fuel Cell' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Energy consumption and production that rely on fossil fuels is forecast to have a severe future impact on world economics and ecology. Electrochemical energy production is under serious consideration as an alternative energy/power source. Systems for electrochemical energy storage and production include batteries and fuel cells, the latter being of greater interest due to the higher availability. Fuel cells are typically classified by the type of electrolyte. The Solid Oxide Fuel Cell (SOFC), where the electrolyte is a solid, has been proposed as the most effective choice due to its versatile choice of fuel, almost quantitative thermodynamic efficiency and tolerance to most impurities. Nevertheless, limitations and problems arise from the high operating temperatures (700 °C) and very humid atmospheres (pH2O = 0.5), which are largely due to the low anionic O2- and protonic H+ conductivities of anionic conductors electrolyte materials. Overall SOFC improvement relies on increasing the conductivities of the electrolyte, which could only be obtained from a mechanism understanding of how O2- and H+ propagate through the electrolyte. We proposed here to tackle these issues by studying the structural chemistry and O2- / H+ dynamics of electrolyte materials under in operando SOFC conditions using Nuclear Magnetic Resonance (NMR) spectroscopy, the most powerful structural determination technique available. The approach will rely on the combined use of state of the art very high field NMR spectrometers, robust solid state NMR probes capable of performing NMR experiments up to 800 °C and endless lists of NMR experiments to obtain structural data and dynamics models covering all timescales. In combination with other in operando techniques (XAS, AC), we aim to obtain mechanisms of c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Role of rab17 protein in epithelial cells', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The small GTP-binding protein, Rab 17 is implicated in the regulation of endocytosis and/or transcytosis in epithelial cells once these cells become polarized. To elucidate the precise functional role of rab 17 protein, we would like to examine whether an overexpression of wild type Rab 17 or dominant interfering mutants affects transcellular transport in cultured polarized epithelial cells. For that, we would like to subclone the cDNA of Rab 17 and Rab 17 mutants defective in GTP-binding, under the control of the MX promoter, an IFNy inductive promoter, and to transfect MDCK cells with these constructs. Then, we will measure the rate of the HRP fluid phase. Moreover, we would like to identify specific proteins interacting with Rab 17 in the aim to define its functional mechanism. We will use both a genetic approach by the double hybrid system in yeast and a biochemical approach to identify factors that regulate the GTP/GDP cycle of Rab 17 and specific effectors.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Completion of activities for Adaptable Communication, Moving Block, Fail safe Train Localisation (including satellite), Zero on site Testing, Formal Methods and Cyber Security', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

X2RAIL-5 is the 5th and last proposal of the Shift2Rail members in the IP2 “Advanced Traffic Management & Control Systems” domain and it aims to continue the research and development of key technologies within the following Technology Demonstrators (TDs):•Adaptable communications (TD2.1): The aim is to test into field trials and validate the adaptable communication system demo taking into account specs and guidelines coming from X2Rail-1 & -3. •Moving Block (TD2.3): The objective of the Demo is to define a Moving Block signalling system, which is applicable across all railway market segments. The scope is to refine the results specifications developed in the projects X2Rail-1 & -3, implement a Demo and include the results in material for 2022 CCS TSI.•Fail-Safe Train Positioning (TD2.4): The objective here is to introduce improved fail-safe train positioning function for ERTMS/ETCS through the application of GNSS and other new technologies as well as other on-board existing sensors. Based on the outputs of X2Rail-2 and other previous projects, demos will be tested in lab and on site.•Zero On-Site Testing (TD2.6): the action will finalise the general architecture, the communication model and will as well perform validation in a testing environment in order to complete the work started in X2Rail-1 & -3 to support automated lab test.•Formal Methods (TD2.7): The objective is to build upon work in X2Rail-2 and pivot to a system of systems perspective and to define a demo linked to LINX4RAIL and its successor (S2R-CFM-IPX & CCA-02-2020).•Cyber Security (TD2.11): The objective is to complete and validate the work done during the projects X2Rail-1 & -3 through:- completion and assessment of the demo - validation of the proposed CSIRT/ISAC model- assessing the protection profile
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Evolution in island birds: testing patterns and investigating mechanisms' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Species on islands are widely believed to undergo similar evolutionary changes as an adaptation to the island environment, a process referred to as the ‘island syndrome’. These changes affect morphological, reproductive, physiological and behavioural traits such as sexual selection. Evolutionary change on islands is believed to relate to genetic (e.g. bottleneck) and ecological factors (e.g. release from natural enemies such as parasites and predators). However, very few broad-scale tests of these patterns have been conducted and few detailed studies examined the underlying processes. Additionally, previous studies were mostly based on data obtained from the literature, which are typically variable in quality. This is surprising given the central role of islands in ecological and evolutionary theory. Whether an ‘island syndrome’ does exist or not can only be established by demonstrating that a set of traits has arisen independently several times in unrelated taxa and geographically distinct areas. We propose to examine whether there are consistent patterns of adaptation in morphological, reproductive and sexually selected traits of island birds worldwide and to investigate some of the underlying causes. To this end, we will first collect standardised data from museum specimens for islands and nearby mainland areas from around the world consisting of morphological, egg and plumage colour measures. Subsequently, we will investigate in detail some of the underlying processes and consequences of evolutionary change on islands in the Gulf of Guinea using weaver (Aves, Ploceidae) species, for which phylogeographic data is available, on the island of São Tomé and nearby mainland Gabon. Specifically, we will address the interaction between decreased parasite pressure, immunity,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Forest environmental monitoring and management system' (FOREMMS), addressing dissemination and exploitation.

assistant: **Impact**

The purpose of this project is to develop and demonstrate an advanced forest environmental monitoring and management system prototype. The operational version of the system is intended to be deployed all over Europe for monitoring forest vegetation resources at regional, national and international (European) scales in order to measure both man-induced and natural changes of the environmental status. The system will utilise and process from field personnel, automatic measurement stations, airborne sensors and satellite data of high and medium resolution with advanced algorithms. The detailed information is measured at point locations around Europe, and the low medium-resolution satellite data is used to extend the data, and will be further investigated with statistical and visualisation tools. The prototype to be developed in the project will be demonstrated at three locations covering the three major European forest types (northern boreal coniferous forest, continental temperate mixed forest and Mediterranean dry forests).Objectives:To develop and demonstrate an advanced forest environmental monitoring and management system prototype;To develop a system that is in accordance with current and future user needs and requirements;To monitor forest resources at the three scales - regional, national and international;To improve and integrate advanced remote sensing technology based on airborne and spaceborne sensors for the extraction of forest environmental parameters;To advance techniques for multi-scale integration of information in order to improve large-scale coverage by scattered information from more detailed scales;To develop techniques for the derivation of forest meta-data/higher-order information from spatial-temporal (4-D) collected data;To contribute to the devel
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Maximization of amplification of next-generation RNA replicon vaccines through synergistic molecular and formulation design' (RNAmpMax).

assistant: **Innovation**

As a Maria Skłodowska-Curie Fellow, I aim to develop formulated next-generation RNA replicons that are designed to overcome the limiting initial type I interferon response that inhibits amplification and protein expression. RNA replicons are currently a cutting edge nucleic acid platform for delivery of vaccines and therapeutics, as they do not require penetration into the nucleus like plasmid DNA, but possess self-amplification properties that results in more efficient protein expression than messenger RNA. While pDNA and mRNA have have demonstrated excellent results with low doses when tested in mice doses must be scaled up by two orders of magnitude to mirror these effects in nonhuman primates. This disparity reflects a non-linear dose-response relationship, where increased doses are associated with triggering of an interferon cascade which restricts protein expression. Under the supervision of Prof. Robin Shattock, a world leader in translational vaccines and clinical trials at Imperial College London, I aim to overcome this translational barrier for RNA replicons by focusing on maximizing protein expression. I intend to engineer synergistic increases in the amplification of RNA replicons through a combination of molecular modifications designed to minimize interferon response and co-delivery with synthetic single-strand oligonucleotides known to inhibit the interferon pathway. These molecular adaptions will be paired with a novel delivery polymer that directly incorporates oligonucleotides into the RNA polyplex, thus ensuring co-localization: to be synthesized in collaboration with Prof. Molly Stevens, a world leader in polymeric biomaterials, during a secondment at the Karolinska Institutet. This project is the first demonstration of synergistic molecular and form
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Structure-function relationships of neurotrophins and their receptors' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Neurotrophic factors are polypeptide hormones required for the development and maintenance of the vertebrate nervous system. The general aim of this proposal is the study of structure-function relationships in a prototypic family of neurotrophic molecules--the neurotrophins--and in their receptors, by applying novel technologies for structure determination and studies of protein-protein interactions. Our first objective will be to determine the crystal structure of the prototypic neurotrophin nerve growth factor (NGF) bound to a minimal fragment of the binding domain of the NGF receptor tyrosine kinase TrkA. Subdomains of TrkA complexed to NGF will also be characterised biophysically to determine conformational changes arising from the interaction of these two proteins. The crystal structure of a TrkANGF complex will be used as a convergence point of rational and random strategies for the design and identification of novel neurotrophin mimetics and inhibitors. For this purpose, we will make use of software packages that use the information provided by a crystallographically determined structure to identify small molecule analogs of NGF. In addition, we will directly investigate the roles of NGF residues forming part of the complex binding interface by engineering, production and characterization of NGF molecules bearing specific mutations. Finally, we will make use of novel techniques for production and screening of combinatorial libraries of molecules displayed on filamentous phage in order to identify novel NGF analogs. These will be applied to the screening and selection of high- affinity soluble TrkA subdomains from a collection of mutagenized TrkA fragments, and of small peptide ligands to TrkA subdomains. All novel NGF mimetics and inhibitors obtained from these a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Leveraging Early Adolescence for Development: Longitudinal and Experimental Evidence from Ghana' (LEAD).

assistant: **Concept**

Early adolescence is a key window for human development. Strategic timing of interventions during this life stage may seize opportunities and prevent risks; bolster the impact of earlier investments; and ease damages from previous adversity. Yet evidence on whether such programs can fulfil this potential, for which children, and through which channels, is scant, especially in low-resource settings, where 90% of the world’s 1.2 billion adolescents live. I will tackle these gaps by relying on a cohort of ~2,500 children approaching early adolescence. In 2015, this sample participated in a trial evaluating quality preschool education in Ghana and has been followed-up since: the program improved child development through middle childhood. I will re-randomise this sample at 12 years to test a parenting skills program to enhance early adolescent development through improved parenting support and parent-adolescent interactions. Children and parents will be re-interviewed when children are 13, 15, and 17 years through mixed-method data collection. Outcomes include adolescent social-emotional and academic skills, health (including stress biomarkers), and adult-life transitions. This data will allow testing dynamic complementarities between interventions during early childhood and early adolescence, or whether interventions in adolescence might compensate for earlier adversity in the short- and longer-term. Methodologically, these questions can be convincingly studied only if data are available for the same individuals over time, and if variations in exposure to early childhood and early adolescence programs are exogenously driven. This is the first study that addresses both requirements, providing a breakthrough. Heterogeneity by child gender and socioeconomic status, and mechan
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project '4x4, demonstrating a flexible value chain to utilize biomass functionalities in the processing industry' (Bio4Products) targeting Horizon 2020.

assistant: **Abstract**

Biomass is a valuable, sustainable feedstock for the production of high added value chemicals and materials, and will play an important role in the transition of the European Process Industry to a Sustainable Process Industry. However, for the optimal utilization of these bio-resources the fractionation of the biomass on basis of functionalities is required. The innovative approach of BIO4PRODUCTS is to apply a short thermal treatment at elevated temperature enabling the fractionation of the bio-resource, but keeping the key chemical functionalities in separate, depolymerized fractions. Within the project the process will be demonstrated in a 3 t/d demo-plant. Subsequently, BIO4PRODUCTS will demonstrate the use of the resulting intermediate processing streams for the production of wood preservation products, furanic resins, phenolic resins and roofing material as cost-effective renewable alternatives for fossil resources in the conventional products (30-100% substitution). Each of the steps in the whole chain has at least been proven on bench-scale (TRL5) and should reach TRL 6-7 by execution of this project. The feedstock flexibility will be shown by demonstrating the complete chain for 4 different biomass resources representative for the majority of biomass resources available in Europe.  Integral topics covered by the project are the techno-economic and environmental assessments as well as the development of business plans for subsequent commercialization of the individual product lines and the overall value chain. The BIO4PRODUCTS consortium consists of 2 large industries and 4 SME’s and 1 one non-profit organization covering the whole chain from biomass collection, primary and secondary conversion, and final use in end products. Additionally, specific expertise is