RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'The role of ROS/RNS during inflammation-associated and sporadic carcinogenesis'.

assistant: **Innovation**

A link between inflammation and cancer has been suspected over a long period of time and in recent years genetic evidence supporting such notion could be obtained. Several signaling pathways, such as NF-κB and STAT3, could be identified by our group as well as other groups to play important roles during tumor promotion and progression. Chronic inflammation leads to the formation of reactive oxygen and nitrogen species, which are known to cause DNA damage and inactivation of DNA repair mechanisms, thereby presumably inducing tumor-initiating mutations. On the other hand, oxidative stress has been documented to trigger apoptosis and cellular senescence. However, in vivo evidence demonstrating the consequences of increased oxidative stress on tumor development in a distinct genetic model is lacking. Selenoproteins of the glutathione peroxidase and thioredoxin reductase family are important anti-oxidant scavenger systems. Using cell type specific inactivation (epithelial cells an myeloid cells) of several of these family members in various well established and relevant models of inflammation-associated and sporadic colon tumorigenesis we will directly examine the role of these anti-oxidant systems. These models will allow us to genetically determine the outcome of increased lipid peroxidation and accumulation of reactive oxygen species in each cell type and to address whether cancer development is supported or inhibited under such conditions and will help to identify which phase of tumor development is affected. Furthermore, we expect to obtain results that will determine whether increased levels of ROS/RNS found during chronic inflammation are capable of initiating tumorigenesis. Our  proposed experiments are supposed to provide fundamental insight into the molecular chang
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Large Deviations and Rare Transitions in Turbulent flows', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Many out-of-equilibrium systems undergo transitions from one quasi-stationary state to a radically different one.Turbulent flows, for instance, exhibit sudden switches between attractors.It is crucial to understand this phenomenon, both for theoretical reasons and for potential applications to industrial or geophysical flows.Indeed, abrupt transitions or tipping points are a critical component of climate dynamics, which is a topic of major importance for society as a whole, in addition to being a  scientific subject of uttermost current interest.Over the past decades, outstanding progress has been achieved in non-equilibrium statistical physics thanks to the theory of large deviations, which provides a natural generalization of the core concepts of equilibrium statistical mechanics: like entropy or free energy, large deviation rate functions encode all the relevant statistical information about an observable, such as its most probable values but also the probability of small and large fluctuations and the transitions between steady-states.However, large deviation computations have been up to now mostly restricted to relatively simple systems.This project will further develop cutting-edge analytical and numerical tools to compute large deviations in complex systems such as turbulent flows and the climate.The new ingredients we will consider are on the one hand, time-dependent attractors, and on the other hand, a complex field structure, since both are key features of geophysical flows.The goal of the project is at the same time to be able to predict some universal features of rare but high-impact transitions in turbulent attractors or, ultimately, the climate, and to promote novel techniques in rare event simulations which are applicable in an increasingly large spectrum
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Creating medically-driven integrative bioinformatics applications focused on oncology, CNS disorders and their comorbidities (MedBioinformatics)' (MedBioinformatics).

assistant: **Concept**

Progress in biomedical research and healthcare requires profiting from the huge amount of data and knowledge that are generated. However, most of the potential users have no means to efficiently exploit this wealth of information. Up to now, many of the efforts done for developing bioinformatics methods and applications have not produced the expected societal impact for different reasons, including: 1) the deficit of integrative approaches that effectively combine different types of data from different sources; and 2) the lack of active involvement of the potential users (from experimental scientists to healthcare professionals) in the process of creating applications that mine, integrate, analyse and display biomedical information in a way that is immediately understandable and useful ('actionable') by the end users. The present project tries to overcome this issue by involving a multidisciplinary team of experienced bioinformaticians, and experimental and clinical scientists in the design and development of demanded bioinformatics applications. The bioinformaticians will develop medical-oriented integrative methods and applications (New Generation Genotype-Phenotype Explorations, Disease Biomarker Browser, Disease Trajectory Comorbidity Browser, Cancer Genome Interpreter, etc.), while the experimental and clinical partners will actively participate in the design and assessment of the applications, as well as in the curation of customized resources.  The experimental and clinical partners belong to two completely different medical specialties (oncology and psychiatry), which have a big impact in citizens’ wellbeing. Moreover, the commonalities existing between the needs of these disparate specialties will facilitate the identification and design of applications likely
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The allocation of durable and non-durable consumption over the life cycle' under Fourth Framework.

assistant: **Concept**

Research objectives and content EMPIRICAL EVALUATION OF CONSUMER'S CHOICE BETWEEN DURABLE AND NON DURABLE CONSUMPTION, TAKING INTO ACCOUNT THE POSSIBILITY OF NON CONVEX ADJUSTMENT COSTS AND OF LIQUIDITY CONSTRAINTS. Training content (objective, benefit and expected impact) TO REACH A DEEPER KNOWLEDGE IN MODELLING INDIVIDUALS BEHAVIOUR AND IN MICRO ECONOMETRIC TECHNIQUES. Links with industry / industrial relevance (22) ESTIMATION AND PREDICTION OF RELATIONS WHICH EXPLAIN MICROECONOMIC BEHAVIOUR OF DURABLE EXPENDITURE.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Continous high rate liquid phase epitaxy of textured coated conductors' to be submitted under Fourth Framework.

assistant: **Abstract**

Objectives and content:The primary objective of this proposal is to develop a novel process for the continuous high rate production of low cost high critical current coated superconductors on metal and ceramic substrates. The proposed programme addresses longer term scientific and technica1 objectives.At the end of the project there will be:1) new scientific knowledge in areas relating to high rate production of coated conductors, and;2) novel patented technology developed to a prototype level for exploitation by European industry. The technique is based on the recent observation of very high growth rates of ReBCO (eg SmBa2Cu307 a) from a supersaturated flux by liquid phase epitaxy (LPE). The key feature of the new process is a patented method to obtain and maintain a high super saturation of the rare earth elements in solution at the superconductor growth interface. This enables the growth rate to be increased by orders of magnitude over both conventional melt processing and competing solution growth techniques. The method also provides novel 'boundary layer' control of liquid supply to the growing super-conducting layer.Coated conductor research has three distinct components: (i) the substrate, (ii) the buffer layer and (iii) the superconducting layer. As a consequence a number of research topics have to be studied within this programme.The new scientific knowledge generated will include improved understanding of: (i) extreme super saturation of the BaCuOflux with multiple rare earth elements, (ii) high rate epitaxial growth of ReBCO, including transient and steady state growth, (iii) novel control of the boundary layer in liquid supply to the substrate, (iv) innovative processes for buffer layer formation, (v) high power dynamic V-I testing for power engineering appl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Network of leading MESOcosm facilities to advance the studies of future AQUAtic ecosystems from the Arctic to the Mediterranean' under Seventh Framework.

assistant: **Concept**

In marine ecology there is an urgent need to understand the functioning of the lower part of the pelagic food web, its response to and effect on climate change, its response to pollution and environmental toxins, and its role in producing food for commercially important species at higher trophic level. This requires access for European scientists to tools allowing experimental approaches to near-natural pelagic systems.  To meet this need, we propose a network (MESOAQUA) of European marine mesocosm facilities.  MESOAQUA will: - Offer European researchers access to a range of mesocosm facilities in contrasting environments.  - Develop and test new technologies that allow access to off-shore environments - Improve the services of the facilities by exchange of technology and experience - Facilitate cross-disciplinary fertilisation and a better coordination of mesocosm research - Promote the training of young scientists in the use of experimental ecosystem research MESOAQUA is necessary because: - System level experimentation is required to understand and predict the responses of the pelagic ecosystem in changing ocean subject to increasing anthropogenic pressure. - There is no present system for trans-national access to such experiemental facilities, particularly not to facilities offering access to different water masses - There is no present technology allowing mesocosm experiments in open waters
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Open Toolset for Mixed Simulation of Multidomain Systems' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

The increasing complexity of products and the necessity to combine multi diciplinary engineering technologies, lead to implement a new generation of software tools for systems modeling design and simulation. Automotive market, in which more and more electronic skill is embedded with traditional mechanical expertise, is going to become an applications area in relevance with the development of this new design tools generation. Actually, obvious and urgent needs are required:  to reduce on board mechatronic systems design phase  to guarantee the reliability of results issued from the design phase.  It becomes so a prime necessity to improve communication between:  specifications levels and technical steps in design, development and test  different multi disciplinary engineering teams  ,external suppliers and assembly units. The efficiency of such a relationship has to be based on the development of a common and global conceptual approach relying on compatible software tools. Unlike digital systems (there are available and efficient simulation tools on the market) there is not so far, mixed simulators enabling to perform and to combine electronical, mechanical and hydraulical functions. Due to the demand, the foreseen growth in mechatronics and the necessity of designing more and more complex systems mixing different engineering technologies, it appeared very critical to focus resources on this matter. Furthermore, VHDL 1076 1 language ,besides its skill in processing analogue and digital phenomena, leads to hopeful developments concerning mixed simulation activities. Obviously, a lot of deficiencies are remaining in this area; there is for example a lack of integration toolsets when it is necessary to proceed in real experimentation's or to obtain an efficient coordination
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Biomass gasification with negative carbon emission through innovative CO2 capture and utilisation and integration with energy storage' (BIOMASS-CCU) under Horizon 2020.

assistant: **Objectives**

This Research and Innovation Staff Exchange project aims to develop and maintain long term collaborations between universities in the EU with China and Australia. This collaboration will build a truly world-leading group through a total of 254 person months of structured international and intersectoral staff exchanges involving 77 individual researchers to innovate next generation low carbon fuel production. Extensive training and knowledge transfer activities will be carried out to enhance career development of the project participants. The research and innovation unites researchers with a common goal to advance biomass gasification technology by integrating CO2 capture and utilisation with multifunctional catalyst materials. Consequently, the BIOMASS-CCU consortium aims to maximize the environmental benefit of carbon emission, and enhance the economic feasibility by producing high value alkenes from CO2 using conventional and advanced non-thermal catalysis. Additionally, through the combination with energy storage and novel heat exchange approaches, energy efficiency of biomass gasification will be significantly enhanced. Extensive techno-economic and life cycle analysis will be carried out to justify the advantages of the proposed biomass gasification technology. BIOMASS-CCU will create a multi-disciplinary consortium consisting of engineers, chemists, material scientists, physicists and applied mathematicians to develop advanced biomass gasification. This project will provide an innovative and economic biomass waste gasification concept for European municipalities, energy production companies and SME’s. The EU partners plan exploitation of the technology through spin-out companies and industrial partnerships. Also, the development of advanced CO2 capture and convers
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Smart Large Scale Radio Technology for the Tactile Internet' (SmartRay).

assistant: **Innovation**

For future mobile wireless services and applications, network operators must deliver exponentially increasing capacity, carrier grade reliability, and efficiency without increasing CAPEX and OPEX significantly. Airrays has developed game changing radio technology for the 4th and 5th generation mobile communication networks that meets these challenges. By using software-controlled beams, Airrays radio units direct signal energy from a cellular base station to exactly where it is needed, e.g., at individual users or hotspots. Compared to state-of-the-art, the technology provides up to 10-fold increased capacity, 10-fold reduced energy consumption, and 10-fold increased reliability, as well as reduced deployment and operational cost of up to 50%. The objective of the innovation project SmartRay is to commercialize Airrays’ advanced antenna technology and to successfully enter the mobile network infrastructure market. Airrays will position themselves initially as component supplier to established infrastructure vendors and antenna manufacturers and, at a later stage, leverage its technology advantage to become vendor of radio units and deliver directly to network operators. This ambition is in line with current disruptive trends in the 4G and 5G infrastructure market where small vendors establish themselves alongside large established players. Through product development as well as successful commercialization Airrays will explicitly strengthen the European communication infrastructure sector. SmartRay Phase 1 will among others conduct a complete FTO analysis, provide detailed product roadmap, and develop a concrete go-to-market strategy to identify an initial market segment to address.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Cultures of Joy in the Metacrisis: Resistance, Resilience, and Repair in Troubled Times' (AnthropoloJOY) under Horizon Europe.

assistant: **Objectives**

Joy is rarely the focus of the social sciences but is arguably more important than it has ever been. While crisis might be a ‘structural signature of modernity’ the experience of crisis today is characterised by complex systems themselves in crisis, interacting with each other in unpredictable ways. This ‘metacrisis’ is ubiquitous, enduring, and emotionally exhausting. Yet, for people around the world, living in and through the metacrisis requires joy to sustain them: experiences of joyous self-transcendence that support political resistance, psychological resilience and social repair.AnthropoloJOY is a novel exploratory investigation into the cross-cultural value, experience and expression of joy in contexts of crisis. The project’s research aims are: 1. To gather much-needed empirical and comparative data on the value, experience, and expression of joy in cross-cultural perspective. 2. To develop an innovative, comparative theoretical framework for understanding joy 3. To establish a new epistemological paradigm for collaborative, more inclusive and increasingly decolonised social science. These aims will be achieved by combining four empirically grounded work packages over the first three years of the project with an agenda-setting position piece in year 4 and an ambitious programme of interdisciplinary outreach and collaboration in year 5. AnthropoloJOY innovates by being the first cross-cultural study of joy grounded in long-term qualitative research methods. Moreover, AnthropoloJOY is rigorously structured around an innovative theoretical approach, a novel combination of qualitative and participatory research methods, and a pioneering commitment to fostering a positive research culture. By modelling new and more expansive ways to conduct collaborative research wit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Improving the competitiveness in the European frozen food industry through the development of new freezing equipment based on CO2' (COMPFREEZE).

assistant: **Concept**

The overall objective of the project is increasing the competitiveness among SMEs in the frozen food industry by developing low temperature freezing equipment enabling the SMEs to increase the productivity.The focus of this proposal will be held on the freezing process losing CO2 as a refrigerant in order to:- Produce knowledge of the connection between the quick-freezing process and quality of the product using various types of freezers in order to control the process.- Implement the developed knowledge in new freezing equipments that ensures better product quality at less operational costs.By using CO2 a safe and environmentally friendly technique is introduced that protects the ozone layer as well as the global warming effects. Recent research programs focus on the performance of the CO2 installation itself. However, the benefits and consequences of using this refrigerant are not well-known or quantified. 10 organisations within the EC have formed a consortium aimed at carrying out the project.